data_8WWI
# 
_entry.id   8WWI 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.398 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8WWI         pdb_00008wwi 10.2210/pdb8wwi/pdb 
WWPDB D_1300040736 ?            ?                   
EMDB  EMD-37889    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2024-11-13 
2 'Structure model' 1 1 2024-11-27 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Data collection' 
# 
_pdbx_audit_revision_category.ordinal             1 
_pdbx_audit_revision_category.revision_ordinal    2 
_pdbx_audit_revision_category.data_content_type   'Structure model' 
_pdbx_audit_revision_category.category            em_admin 
# 
_pdbx_audit_revision_item.ordinal             1 
_pdbx_audit_revision_item.revision_ordinal    2 
_pdbx_audit_revision_item.data_content_type   'Structure model' 
_pdbx_audit_revision_item.item                '_em_admin.last_update' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8WWI 
_pdbx_database_status.recvd_initial_deposition_date   2023-10-25 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'MCHR1-Gi complex,S3 state' 
_pdbx_database_related.db_id          EMD-37889 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              wgong@ustc.edu.cn 
_pdbx_contact_author.name_first         Weimin 
_pdbx_contact_author.name_last          Gong 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-6723-1298 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Gong, W.' 1 0000-0002-6723-1298 
'Ye, X.'   2 0009-0008-6388-0873 
'Liu, G.'  3 0009-0005-7555-0167 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Structural insights into ligand recognition and activation of melanin-concentrating hormone receptor MCHR1' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Gong, W.' 1 0000-0002-6723-1298 
primary 'Ye, X.'   2 0009-0008-6388-0873 
primary 'Liu, G.'  3 0009-0005-7555-0167 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'Guanine nucleotide-binding protein G(i) subunit alpha-1'                    40414.047 1 ? ? ? ? 
2 polymer man 'Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1'           40845.559 1 ? ? ? ? 
3 polymer man 'Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2'          7861.143  1 ? ? ? ? 
4 polymer man 'Antibody fragment ScFv16'                                                   27374.430 1 ? ? ? ? 
5 polymer man 'Fusion protein 1,Melanin-concentrating hormone receptor 1,Fusion protein 2' 68207.039 1 ? ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'Adenylate cyclase-inhibiting G alpha protein'                                                                          
2 'Transducin beta chain 1'                                                                                               
3 'G gamma-I'                                                                                                             
5 'MCH receptor 1,MCH-R1,MCHR-1,G-protein coupled receptor 24,MCH-1R,MCH1R,MCHR,SLC-1,Somatostatin receptor-like protein' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKNTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQS
IIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLD
RIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGAQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM
NRMHASMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIY
THFTCSTDTKNVQFVFDAVTDVIIKNNLKDCGLF
;
;MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKNTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQS
IIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLD
RIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGAQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM
NRMHASMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIY
THFTCSTDTKNVQFVFDAVTDVIIKNNLKDCGLF
;
A ? 
2 'polypeptide(L)' no no 
;MHHHHHHGSSGSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLL
VSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCR
FLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDIN
AICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAG
HDNRVSCLGVTDDGMAVATGSWDSFLKIWNGSSGGGGSGGGGSSGVSGWRLFKKIS
;
;MHHHHHHGSSGSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLL
VSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCR
FLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDIN
AICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAG
HDNRVSCLGVTDDGMAVATGSWDSFLKIWNGSSGGGGSGGGGSSGVSGWRLFKKIS
;
B ? 
3 'polypeptide(L)' no no MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL 
MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL C ? 
4 'polypeptide(L)' no no 
;DVQLVESGGGLVQPGGSRKLSCSASGFAFSSFGMHWVRQAPEKGLEWVAYISSGSGTIYYADTVKGRFTISRDDPKNTLF
LQMTSLRSEDTAMYYCVRSIYYYGSSPFDFWGQGTTLTVSSGGGGSGGGGSGGGGSDIVMTQATSSVPVTPGESVSISCR
SSKSLLHSNGNTYLYWFLQRPGQSPQLLIYRMSNLASGVPDRFSGSGSGTAFTLTISRLEAEDVGVYYCMQHLEYPLTFG
AGTKLELLEENLYFQ
;
;DVQLVESGGGLVQPGGSRKLSCSASGFAFSSFGMHWVRQAPEKGLEWVAYISSGSGTIYYADTVKGRFTISRDDPKNTLF
LQMTSLRSEDTAMYYCVRSIYYYGSSPFDFWGQGTTLTVSSGGGGSGGGGSGGGGSDIVMTQATSSVPVTPGESVSISCR
SSKSLLHSNGNTYLYWFLQRPGQSPQLLIYRMSNLASGVPDRFSGSGSGTAFTLTISRLEAEDVGVYYCMQHLEYPLTFG
AGTKLELLEENLYFQ
;
E ? 
5 'polypeptide(L)' no no 
;DYKDDDDHHHHHHHHGQPGNGSAFLLAPNGSHAPDHNVTQQRDEENLYFQGVDMSVGAMKKGVGRAVGLGGGSGCQATEE
DPLPNCGACAPGQGGRRWRLPQPAWVEGSSARLWEQATGTGWMDLEASLLPTGPNASNTSDGPDNLTSAGSPPRTGSISY
INIIMPSVFGTICLLGIIGNSTVIFAVVKKSKLHWCNNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTL
ITAMDANSQFTSTYILTAMAIDRYLATVHPISSTKFRKPSVATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRL
PNPDTDLYWFTLYQFFLAFALPFVVITAAYVRILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLT
QLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKHMGSSGGGGSGGGGSSGVFTLEDFVGDWEQT
AAYNLDQVLEQGGVSSLLQNLAVSVTPIQRIVRSGENALKIDIHVIIPYEGLSADQMAQIEEVFKVVYPVDDHHFKVILP
YGTLVIDGVTPNMLNYFGRPYEGIAVFDGKKITVTGTLWNGNKIIDERLITPDGSMLFRVTINS
;
;DYKDDDDHHHHHHHHGQPGNGSAFLLAPNGSHAPDHNVTQQRDEENLYFQGVDMSVGAMKKGVGRAVGLGGGSGCQATEE
DPLPNCGACAPGQGGRRWRLPQPAWVEGSSARLWEQATGTGWMDLEASLLPTGPNASNTSDGPDNLTSAGSPPRTGSISY
INIIMPSVFGTICLLGIIGNSTVIFAVVKKSKLHWCNNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTL
ITAMDANSQFTSTYILTAMAIDRYLATVHPISSTKFRKPSVATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRL
PNPDTDLYWFTLYQFFLAFALPFVVITAAYVRILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLT
QLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKHMGSSGGGGSGGGGSSGVFTLEDFVGDWEQT
AAYNLDQVLEQGGVSSLLQNLAVSVTPIQRIVRSGENALKIDIHVIIPYEGLSADQMAQIEEVFKVVYPVDDHHFKVILP
YGTLVIDGVTPNMLNYFGRPYEGIAVFDGKKITVTGTLWNGNKIIDERLITPDGSMLFRVTINS
;
R ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLY n 
1 3   CYS n 
1 4   THR n 
1 5   LEU n 
1 6   SER n 
1 7   ALA n 
1 8   GLU n 
1 9   ASP n 
1 10  LYS n 
1 11  ALA n 
1 12  ALA n 
1 13  VAL n 
1 14  GLU n 
1 15  ARG n 
1 16  SER n 
1 17  LYS n 
1 18  MET n 
1 19  ILE n 
1 20  ASP n 
1 21  ARG n 
1 22  ASN n 
1 23  LEU n 
1 24  ARG n 
1 25  GLU n 
1 26  ASP n 
1 27  GLY n 
1 28  GLU n 
1 29  LYS n 
1 30  ALA n 
1 31  ALA n 
1 32  ARG n 
1 33  GLU n 
1 34  VAL n 
1 35  LYS n 
1 36  LEU n 
1 37  LEU n 
1 38  LEU n 
1 39  LEU n 
1 40  GLY n 
1 41  ALA n 
1 42  GLY n 
1 43  GLU n 
1 44  SER n 
1 45  GLY n 
1 46  LYS n 
1 47  ASN n 
1 48  THR n 
1 49  ILE n 
1 50  VAL n 
1 51  LYS n 
1 52  GLN n 
1 53  MET n 
1 54  LYS n 
1 55  ILE n 
1 56  ILE n 
1 57  HIS n 
1 58  GLU n 
1 59  ALA n 
1 60  GLY n 
1 61  TYR n 
1 62  SER n 
1 63  GLU n 
1 64  GLU n 
1 65  GLU n 
1 66  CYS n 
1 67  LYS n 
1 68  GLN n 
1 69  TYR n 
1 70  LYS n 
1 71  ALA n 
1 72  VAL n 
1 73  VAL n 
1 74  TYR n 
1 75  SER n 
1 76  ASN n 
1 77  THR n 
1 78  ILE n 
1 79  GLN n 
1 80  SER n 
1 81  ILE n 
1 82  ILE n 
1 83  ALA n 
1 84  ILE n 
1 85  ILE n 
1 86  ARG n 
1 87  ALA n 
1 88  MET n 
1 89  GLY n 
1 90  ARG n 
1 91  LEU n 
1 92  LYS n 
1 93  ILE n 
1 94  ASP n 
1 95  PHE n 
1 96  GLY n 
1 97  ASP n 
1 98  SER n 
1 99  ALA n 
1 100 ARG n 
1 101 ALA n 
1 102 ASP n 
1 103 ASP n 
1 104 ALA n 
1 105 ARG n 
1 106 GLN n 
1 107 LEU n 
1 108 PHE n 
1 109 VAL n 
1 110 LEU n 
1 111 ALA n 
1 112 GLY n 
1 113 ALA n 
1 114 ALA n 
1 115 GLU n 
1 116 GLU n 
1 117 GLY n 
1 118 PHE n 
1 119 MET n 
1 120 THR n 
1 121 ALA n 
1 122 GLU n 
1 123 LEU n 
1 124 ALA n 
1 125 GLY n 
1 126 VAL n 
1 127 ILE n 
1 128 LYS n 
1 129 ARG n 
1 130 LEU n 
1 131 TRP n 
1 132 LYS n 
1 133 ASP n 
1 134 SER n 
1 135 GLY n 
1 136 VAL n 
1 137 GLN n 
1 138 ALA n 
1 139 CYS n 
1 140 PHE n 
1 141 ASN n 
1 142 ARG n 
1 143 SER n 
1 144 ARG n 
1 145 GLU n 
1 146 TYR n 
1 147 GLN n 
1 148 LEU n 
1 149 ASN n 
1 150 ASP n 
1 151 SER n 
1 152 ALA n 
1 153 ALA n 
1 154 TYR n 
1 155 TYR n 
1 156 LEU n 
1 157 ASN n 
1 158 ASP n 
1 159 LEU n 
1 160 ASP n 
1 161 ARG n 
1 162 ILE n 
1 163 ALA n 
1 164 GLN n 
1 165 PRO n 
1 166 ASN n 
1 167 TYR n 
1 168 ILE n 
1 169 PRO n 
1 170 THR n 
1 171 GLN n 
1 172 GLN n 
1 173 ASP n 
1 174 VAL n 
1 175 LEU n 
1 176 ARG n 
1 177 THR n 
1 178 ARG n 
1 179 VAL n 
1 180 LYS n 
1 181 THR n 
1 182 THR n 
1 183 GLY n 
1 184 ILE n 
1 185 VAL n 
1 186 GLU n 
1 187 THR n 
1 188 HIS n 
1 189 PHE n 
1 190 THR n 
1 191 PHE n 
1 192 LYS n 
1 193 ASP n 
1 194 LEU n 
1 195 HIS n 
1 196 PHE n 
1 197 LYS n 
1 198 MET n 
1 199 PHE n 
1 200 ASP n 
1 201 VAL n 
1 202 GLY n 
1 203 ALA n 
1 204 GLN n 
1 205 ARG n 
1 206 SER n 
1 207 GLU n 
1 208 ARG n 
1 209 LYS n 
1 210 LYS n 
1 211 TRP n 
1 212 ILE n 
1 213 HIS n 
1 214 CYS n 
1 215 PHE n 
1 216 GLU n 
1 217 GLY n 
1 218 VAL n 
1 219 THR n 
1 220 ALA n 
1 221 ILE n 
1 222 ILE n 
1 223 PHE n 
1 224 CYS n 
1 225 VAL n 
1 226 ALA n 
1 227 LEU n 
1 228 SER n 
1 229 ASP n 
1 230 TYR n 
1 231 ASP n 
1 232 LEU n 
1 233 VAL n 
1 234 LEU n 
1 235 ALA n 
1 236 GLU n 
1 237 ASP n 
1 238 GLU n 
1 239 GLU n 
1 240 MET n 
1 241 ASN n 
1 242 ARG n 
1 243 MET n 
1 244 HIS n 
1 245 ALA n 
1 246 SER n 
1 247 MET n 
1 248 LYS n 
1 249 LEU n 
1 250 PHE n 
1 251 ASP n 
1 252 SER n 
1 253 ILE n 
1 254 CYS n 
1 255 ASN n 
1 256 ASN n 
1 257 LYS n 
1 258 TRP n 
1 259 PHE n 
1 260 THR n 
1 261 ASP n 
1 262 THR n 
1 263 SER n 
1 264 ILE n 
1 265 ILE n 
1 266 LEU n 
1 267 PHE n 
1 268 LEU n 
1 269 ASN n 
1 270 LYS n 
1 271 LYS n 
1 272 ASP n 
1 273 LEU n 
1 274 PHE n 
1 275 GLU n 
1 276 GLU n 
1 277 LYS n 
1 278 ILE n 
1 279 LYS n 
1 280 LYS n 
1 281 SER n 
1 282 PRO n 
1 283 LEU n 
1 284 THR n 
1 285 ILE n 
1 286 CYS n 
1 287 TYR n 
1 288 PRO n 
1 289 GLU n 
1 290 TYR n 
1 291 ALA n 
1 292 GLY n 
1 293 SER n 
1 294 ASN n 
1 295 THR n 
1 296 TYR n 
1 297 GLU n 
1 298 GLU n 
1 299 ALA n 
1 300 ALA n 
1 301 ALA n 
1 302 TYR n 
1 303 ILE n 
1 304 GLN n 
1 305 CYS n 
1 306 GLN n 
1 307 PHE n 
1 308 GLU n 
1 309 ASP n 
1 310 LEU n 
1 311 ASN n 
1 312 LYS n 
1 313 ARG n 
1 314 LYS n 
1 315 ASP n 
1 316 THR n 
1 317 LYS n 
1 318 GLU n 
1 319 ILE n 
1 320 TYR n 
1 321 THR n 
1 322 HIS n 
1 323 PHE n 
1 324 THR n 
1 325 CYS n 
1 326 SER n 
1 327 THR n 
1 328 ASP n 
1 329 THR n 
1 330 LYS n 
1 331 ASN n 
1 332 VAL n 
1 333 GLN n 
1 334 PHE n 
1 335 VAL n 
1 336 PHE n 
1 337 ASP n 
1 338 ALA n 
1 339 VAL n 
1 340 THR n 
1 341 ASP n 
1 342 VAL n 
1 343 ILE n 
1 344 ILE n 
1 345 LYS n 
1 346 ASN n 
1 347 ASN n 
1 348 LEU n 
1 349 LYS n 
1 350 ASP n 
1 351 CYS n 
1 352 GLY n 
1 353 LEU n 
1 354 PHE n 
2 1   MET n 
2 2   HIS n 
2 3   HIS n 
2 4   HIS n 
2 5   HIS n 
2 6   HIS n 
2 7   HIS n 
2 8   GLY n 
2 9   SER n 
2 10  SER n 
2 11  GLY n 
2 12  SER n 
2 13  GLU n 
2 14  LEU n 
2 15  ASP n 
2 16  GLN n 
2 17  LEU n 
2 18  ARG n 
2 19  GLN n 
2 20  GLU n 
2 21  ALA n 
2 22  GLU n 
2 23  GLN n 
2 24  LEU n 
2 25  LYS n 
2 26  ASN n 
2 27  GLN n 
2 28  ILE n 
2 29  ARG n 
2 30  ASP n 
2 31  ALA n 
2 32  ARG n 
2 33  LYS n 
2 34  ALA n 
2 35  CYS n 
2 36  ALA n 
2 37  ASP n 
2 38  ALA n 
2 39  THR n 
2 40  LEU n 
2 41  SER n 
2 42  GLN n 
2 43  ILE n 
2 44  THR n 
2 45  ASN n 
2 46  ASN n 
2 47  ILE n 
2 48  ASP n 
2 49  PRO n 
2 50  VAL n 
2 51  GLY n 
2 52  ARG n 
2 53  ILE n 
2 54  GLN n 
2 55  MET n 
2 56  ARG n 
2 57  THR n 
2 58  ARG n 
2 59  ARG n 
2 60  THR n 
2 61  LEU n 
2 62  ARG n 
2 63  GLY n 
2 64  HIS n 
2 65  LEU n 
2 66  ALA n 
2 67  LYS n 
2 68  ILE n 
2 69  TYR n 
2 70  ALA n 
2 71  MET n 
2 72  HIS n 
2 73  TRP n 
2 74  GLY n 
2 75  THR n 
2 76  ASP n 
2 77  SER n 
2 78  ARG n 
2 79  LEU n 
2 80  LEU n 
2 81  VAL n 
2 82  SER n 
2 83  ALA n 
2 84  SER n 
2 85  GLN n 
2 86  ASP n 
2 87  GLY n 
2 88  LYS n 
2 89  LEU n 
2 90  ILE n 
2 91  ILE n 
2 92  TRP n 
2 93  ASP n 
2 94  SER n 
2 95  TYR n 
2 96  THR n 
2 97  THR n 
2 98  ASN n 
2 99  LYS n 
2 100 VAL n 
2 101 HIS n 
2 102 ALA n 
2 103 ILE n 
2 104 PRO n 
2 105 LEU n 
2 106 ARG n 
2 107 SER n 
2 108 SER n 
2 109 TRP n 
2 110 VAL n 
2 111 MET n 
2 112 THR n 
2 113 CYS n 
2 114 ALA n 
2 115 TYR n 
2 116 ALA n 
2 117 PRO n 
2 118 SER n 
2 119 GLY n 
2 120 ASN n 
2 121 TYR n 
2 122 VAL n 
2 123 ALA n 
2 124 CYS n 
2 125 GLY n 
2 126 GLY n 
2 127 LEU n 
2 128 ASP n 
2 129 ASN n 
2 130 ILE n 
2 131 CYS n 
2 132 SER n 
2 133 ILE n 
2 134 TYR n 
2 135 ASN n 
2 136 LEU n 
2 137 LYS n 
2 138 THR n 
2 139 ARG n 
2 140 GLU n 
2 141 GLY n 
2 142 ASN n 
2 143 VAL n 
2 144 ARG n 
2 145 VAL n 
2 146 SER n 
2 147 ARG n 
2 148 GLU n 
2 149 LEU n 
2 150 ALA n 
2 151 GLY n 
2 152 HIS n 
2 153 THR n 
2 154 GLY n 
2 155 TYR n 
2 156 LEU n 
2 157 SER n 
2 158 CYS n 
2 159 CYS n 
2 160 ARG n 
2 161 PHE n 
2 162 LEU n 
2 163 ASP n 
2 164 ASP n 
2 165 ASN n 
2 166 GLN n 
2 167 ILE n 
2 168 VAL n 
2 169 THR n 
2 170 SER n 
2 171 SER n 
2 172 GLY n 
2 173 ASP n 
2 174 THR n 
2 175 THR n 
2 176 CYS n 
2 177 ALA n 
2 178 LEU n 
2 179 TRP n 
2 180 ASP n 
2 181 ILE n 
2 182 GLU n 
2 183 THR n 
2 184 GLY n 
2 185 GLN n 
2 186 GLN n 
2 187 THR n 
2 188 THR n 
2 189 THR n 
2 190 PHE n 
2 191 THR n 
2 192 GLY n 
2 193 HIS n 
2 194 THR n 
2 195 GLY n 
2 196 ASP n 
2 197 VAL n 
2 198 MET n 
2 199 SER n 
2 200 LEU n 
2 201 SER n 
2 202 LEU n 
2 203 ALA n 
2 204 PRO n 
2 205 ASP n 
2 206 THR n 
2 207 ARG n 
2 208 LEU n 
2 209 PHE n 
2 210 VAL n 
2 211 SER n 
2 212 GLY n 
2 213 ALA n 
2 214 CYS n 
2 215 ASP n 
2 216 ALA n 
2 217 SER n 
2 218 ALA n 
2 219 LYS n 
2 220 LEU n 
2 221 TRP n 
2 222 ASP n 
2 223 VAL n 
2 224 ARG n 
2 225 GLU n 
2 226 GLY n 
2 227 MET n 
2 228 CYS n 
2 229 ARG n 
2 230 GLN n 
2 231 THR n 
2 232 PHE n 
2 233 THR n 
2 234 GLY n 
2 235 HIS n 
2 236 GLU n 
2 237 SER n 
2 238 ASP n 
2 239 ILE n 
2 240 ASN n 
2 241 ALA n 
2 242 ILE n 
2 243 CYS n 
2 244 PHE n 
2 245 PHE n 
2 246 PRO n 
2 247 ASN n 
2 248 GLY n 
2 249 ASN n 
2 250 ALA n 
2 251 PHE n 
2 252 ALA n 
2 253 THR n 
2 254 GLY n 
2 255 SER n 
2 256 ASP n 
2 257 ASP n 
2 258 ALA n 
2 259 THR n 
2 260 CYS n 
2 261 ARG n 
2 262 LEU n 
2 263 PHE n 
2 264 ASP n 
2 265 LEU n 
2 266 ARG n 
2 267 ALA n 
2 268 ASP n 
2 269 GLN n 
2 270 GLU n 
2 271 LEU n 
2 272 MET n 
2 273 THR n 
2 274 TYR n 
2 275 SER n 
2 276 HIS n 
2 277 ASP n 
2 278 ASN n 
2 279 ILE n 
2 280 ILE n 
2 281 CYS n 
2 282 GLY n 
2 283 ILE n 
2 284 THR n 
2 285 SER n 
2 286 VAL n 
2 287 SER n 
2 288 PHE n 
2 289 SER n 
2 290 LYS n 
2 291 SER n 
2 292 GLY n 
2 293 ARG n 
2 294 LEU n 
2 295 LEU n 
2 296 LEU n 
2 297 ALA n 
2 298 GLY n 
2 299 TYR n 
2 300 ASP n 
2 301 ASP n 
2 302 PHE n 
2 303 ASN n 
2 304 CYS n 
2 305 ASN n 
2 306 VAL n 
2 307 TRP n 
2 308 ASP n 
2 309 ALA n 
2 310 LEU n 
2 311 LYS n 
2 312 ALA n 
2 313 ASP n 
2 314 ARG n 
2 315 ALA n 
2 316 GLY n 
2 317 VAL n 
2 318 LEU n 
2 319 ALA n 
2 320 GLY n 
2 321 HIS n 
2 322 ASP n 
2 323 ASN n 
2 324 ARG n 
2 325 VAL n 
2 326 SER n 
2 327 CYS n 
2 328 LEU n 
2 329 GLY n 
2 330 VAL n 
2 331 THR n 
2 332 ASP n 
2 333 ASP n 
2 334 GLY n 
2 335 MET n 
2 336 ALA n 
2 337 VAL n 
2 338 ALA n 
2 339 THR n 
2 340 GLY n 
2 341 SER n 
2 342 TRP n 
2 343 ASP n 
2 344 SER n 
2 345 PHE n 
2 346 LEU n 
2 347 LYS n 
2 348 ILE n 
2 349 TRP n 
2 350 ASN n 
2 351 GLY n 
2 352 SER n 
2 353 SER n 
2 354 GLY n 
2 355 GLY n 
2 356 GLY n 
2 357 GLY n 
2 358 SER n 
2 359 GLY n 
2 360 GLY n 
2 361 GLY n 
2 362 GLY n 
2 363 SER n 
2 364 SER n 
2 365 GLY n 
2 366 VAL n 
2 367 SER n 
2 368 GLY n 
2 369 TRP n 
2 370 ARG n 
2 371 LEU n 
2 372 PHE n 
2 373 LYS n 
2 374 LYS n 
2 375 ILE n 
2 376 SER n 
3 1   MET n 
3 2   ALA n 
3 3   SER n 
3 4   ASN n 
3 5   ASN n 
3 6   THR n 
3 7   ALA n 
3 8   SER n 
3 9   ILE n 
3 10  ALA n 
3 11  GLN n 
3 12  ALA n 
3 13  ARG n 
3 14  LYS n 
3 15  LEU n 
3 16  VAL n 
3 17  GLU n 
3 18  GLN n 
3 19  LEU n 
3 20  LYS n 
3 21  MET n 
3 22  GLU n 
3 23  ALA n 
3 24  ASN n 
3 25  ILE n 
3 26  ASP n 
3 27  ARG n 
3 28  ILE n 
3 29  LYS n 
3 30  VAL n 
3 31  SER n 
3 32  LYS n 
3 33  ALA n 
3 34  ALA n 
3 35  ALA n 
3 36  ASP n 
3 37  LEU n 
3 38  MET n 
3 39  ALA n 
3 40  TYR n 
3 41  CYS n 
3 42  GLU n 
3 43  ALA n 
3 44  HIS n 
3 45  ALA n 
3 46  LYS n 
3 47  GLU n 
3 48  ASP n 
3 49  PRO n 
3 50  LEU n 
3 51  LEU n 
3 52  THR n 
3 53  PRO n 
3 54  VAL n 
3 55  PRO n 
3 56  ALA n 
3 57  SER n 
3 58  GLU n 
3 59  ASN n 
3 60  PRO n 
3 61  PHE n 
3 62  ARG n 
3 63  GLU n 
3 64  LYS n 
3 65  LYS n 
3 66  PHE n 
3 67  PHE n 
3 68  CYS n 
3 69  ALA n 
3 70  ILE n 
3 71  LEU n 
4 1   ASP n 
4 2   VAL n 
4 3   GLN n 
4 4   LEU n 
4 5   VAL n 
4 6   GLU n 
4 7   SER n 
4 8   GLY n 
4 9   GLY n 
4 10  GLY n 
4 11  LEU n 
4 12  VAL n 
4 13  GLN n 
4 14  PRO n 
4 15  GLY n 
4 16  GLY n 
4 17  SER n 
4 18  ARG n 
4 19  LYS n 
4 20  LEU n 
4 21  SER n 
4 22  CYS n 
4 23  SER n 
4 24  ALA n 
4 25  SER n 
4 26  GLY n 
4 27  PHE n 
4 28  ALA n 
4 29  PHE n 
4 30  SER n 
4 31  SER n 
4 32  PHE n 
4 33  GLY n 
4 34  MET n 
4 35  HIS n 
4 36  TRP n 
4 37  VAL n 
4 38  ARG n 
4 39  GLN n 
4 40  ALA n 
4 41  PRO n 
4 42  GLU n 
4 43  LYS n 
4 44  GLY n 
4 45  LEU n 
4 46  GLU n 
4 47  TRP n 
4 48  VAL n 
4 49  ALA n 
4 50  TYR n 
4 51  ILE n 
4 52  SER n 
4 53  SER n 
4 54  GLY n 
4 55  SER n 
4 56  GLY n 
4 57  THR n 
4 58  ILE n 
4 59  TYR n 
4 60  TYR n 
4 61  ALA n 
4 62  ASP n 
4 63  THR n 
4 64  VAL n 
4 65  LYS n 
4 66  GLY n 
4 67  ARG n 
4 68  PHE n 
4 69  THR n 
4 70  ILE n 
4 71  SER n 
4 72  ARG n 
4 73  ASP n 
4 74  ASP n 
4 75  PRO n 
4 76  LYS n 
4 77  ASN n 
4 78  THR n 
4 79  LEU n 
4 80  PHE n 
4 81  LEU n 
4 82  GLN n 
4 83  MET n 
4 84  THR n 
4 85  SER n 
4 86  LEU n 
4 87  ARG n 
4 88  SER n 
4 89  GLU n 
4 90  ASP n 
4 91  THR n 
4 92  ALA n 
4 93  MET n 
4 94  TYR n 
4 95  TYR n 
4 96  CYS n 
4 97  VAL n 
4 98  ARG n 
4 99  SER n 
4 100 ILE n 
4 101 TYR n 
4 102 TYR n 
4 103 TYR n 
4 104 GLY n 
4 105 SER n 
4 106 SER n 
4 107 PRO n 
4 108 PHE n 
4 109 ASP n 
4 110 PHE n 
4 111 TRP n 
4 112 GLY n 
4 113 GLN n 
4 114 GLY n 
4 115 THR n 
4 116 THR n 
4 117 LEU n 
4 118 THR n 
4 119 VAL n 
4 120 SER n 
4 121 SER n 
4 122 GLY n 
4 123 GLY n 
4 124 GLY n 
4 125 GLY n 
4 126 SER n 
4 127 GLY n 
4 128 GLY n 
4 129 GLY n 
4 130 GLY n 
4 131 SER n 
4 132 GLY n 
4 133 GLY n 
4 134 GLY n 
4 135 GLY n 
4 136 SER n 
4 137 ASP n 
4 138 ILE n 
4 139 VAL n 
4 140 MET n 
4 141 THR n 
4 142 GLN n 
4 143 ALA n 
4 144 THR n 
4 145 SER n 
4 146 SER n 
4 147 VAL n 
4 148 PRO n 
4 149 VAL n 
4 150 THR n 
4 151 PRO n 
4 152 GLY n 
4 153 GLU n 
4 154 SER n 
4 155 VAL n 
4 156 SER n 
4 157 ILE n 
4 158 SER n 
4 159 CYS n 
4 160 ARG n 
4 161 SER n 
4 162 SER n 
4 163 LYS n 
4 164 SER n 
4 165 LEU n 
4 166 LEU n 
4 167 HIS n 
4 168 SER n 
4 169 ASN n 
4 170 GLY n 
4 171 ASN n 
4 172 THR n 
4 173 TYR n 
4 174 LEU n 
4 175 TYR n 
4 176 TRP n 
4 177 PHE n 
4 178 LEU n 
4 179 GLN n 
4 180 ARG n 
4 181 PRO n 
4 182 GLY n 
4 183 GLN n 
4 184 SER n 
4 185 PRO n 
4 186 GLN n 
4 187 LEU n 
4 188 LEU n 
4 189 ILE n 
4 190 TYR n 
4 191 ARG n 
4 192 MET n 
4 193 SER n 
4 194 ASN n 
4 195 LEU n 
4 196 ALA n 
4 197 SER n 
4 198 GLY n 
4 199 VAL n 
4 200 PRO n 
4 201 ASP n 
4 202 ARG n 
4 203 PHE n 
4 204 SER n 
4 205 GLY n 
4 206 SER n 
4 207 GLY n 
4 208 SER n 
4 209 GLY n 
4 210 THR n 
4 211 ALA n 
4 212 PHE n 
4 213 THR n 
4 214 LEU n 
4 215 THR n 
4 216 ILE n 
4 217 SER n 
4 218 ARG n 
4 219 LEU n 
4 220 GLU n 
4 221 ALA n 
4 222 GLU n 
4 223 ASP n 
4 224 VAL n 
4 225 GLY n 
4 226 VAL n 
4 227 TYR n 
4 228 TYR n 
4 229 CYS n 
4 230 MET n 
4 231 GLN n 
4 232 HIS n 
4 233 LEU n 
4 234 GLU n 
4 235 TYR n 
4 236 PRO n 
4 237 LEU n 
4 238 THR n 
4 239 PHE n 
4 240 GLY n 
4 241 ALA n 
4 242 GLY n 
4 243 THR n 
4 244 LYS n 
4 245 LEU n 
4 246 GLU n 
4 247 LEU n 
4 248 LEU n 
4 249 GLU n 
4 250 GLU n 
4 251 ASN n 
4 252 LEU n 
4 253 TYR n 
4 254 PHE n 
4 255 GLN n 
5 1   ASP n 
5 2   TYR n 
5 3   LYS n 
5 4   ASP n 
5 5   ASP n 
5 6   ASP n 
5 7   ASP n 
5 8   HIS n 
5 9   HIS n 
5 10  HIS n 
5 11  HIS n 
5 12  HIS n 
5 13  HIS n 
5 14  HIS n 
5 15  HIS n 
5 16  GLY n 
5 17  GLN n 
5 18  PRO n 
5 19  GLY n 
5 20  ASN n 
5 21  GLY n 
5 22  SER n 
5 23  ALA n 
5 24  PHE n 
5 25  LEU n 
5 26  LEU n 
5 27  ALA n 
5 28  PRO n 
5 29  ASN n 
5 30  GLY n 
5 31  SER n 
5 32  HIS n 
5 33  ALA n 
5 34  PRO n 
5 35  ASP n 
5 36  HIS n 
5 37  ASN n 
5 38  VAL n 
5 39  THR n 
5 40  GLN n 
5 41  GLN n 
5 42  ARG n 
5 43  ASP n 
5 44  GLU n 
5 45  GLU n 
5 46  ASN n 
5 47  LEU n 
5 48  TYR n 
5 49  PHE n 
5 50  GLN n 
5 51  GLY n 
5 52  VAL n 
5 53  ASP n 
5 54  MET n 
5 55  SER n 
5 56  VAL n 
5 57  GLY n 
5 58  ALA n 
5 59  MET n 
5 60  LYS n 
5 61  LYS n 
5 62  GLY n 
5 63  VAL n 
5 64  GLY n 
5 65  ARG n 
5 66  ALA n 
5 67  VAL n 
5 68  GLY n 
5 69  LEU n 
5 70  GLY n 
5 71  GLY n 
5 72  GLY n 
5 73  SER n 
5 74  GLY n 
5 75  CYS n 
5 76  GLN n 
5 77  ALA n 
5 78  THR n 
5 79  GLU n 
5 80  GLU n 
5 81  ASP n 
5 82  PRO n 
5 83  LEU n 
5 84  PRO n 
5 85  ASN n 
5 86  CYS n 
5 87  GLY n 
5 88  ALA n 
5 89  CYS n 
5 90  ALA n 
5 91  PRO n 
5 92  GLY n 
5 93  GLN n 
5 94  GLY n 
5 95  GLY n 
5 96  ARG n 
5 97  ARG n 
5 98  TRP n 
5 99  ARG n 
5 100 LEU n 
5 101 PRO n 
5 102 GLN n 
5 103 PRO n 
5 104 ALA n 
5 105 TRP n 
5 106 VAL n 
5 107 GLU n 
5 108 GLY n 
5 109 SER n 
5 110 SER n 
5 111 ALA n 
5 112 ARG n 
5 113 LEU n 
5 114 TRP n 
5 115 GLU n 
5 116 GLN n 
5 117 ALA n 
5 118 THR n 
5 119 GLY n 
5 120 THR n 
5 121 GLY n 
5 122 TRP n 
5 123 MET n 
5 124 ASP n 
5 125 LEU n 
5 126 GLU n 
5 127 ALA n 
5 128 SER n 
5 129 LEU n 
5 130 LEU n 
5 131 PRO n 
5 132 THR n 
5 133 GLY n 
5 134 PRO n 
5 135 ASN n 
5 136 ALA n 
5 137 SER n 
5 138 ASN n 
5 139 THR n 
5 140 SER n 
5 141 ASP n 
5 142 GLY n 
5 143 PRO n 
5 144 ASP n 
5 145 ASN n 
5 146 LEU n 
5 147 THR n 
5 148 SER n 
5 149 ALA n 
5 150 GLY n 
5 151 SER n 
5 152 PRO n 
5 153 PRO n 
5 154 ARG n 
5 155 THR n 
5 156 GLY n 
5 157 SER n 
5 158 ILE n 
5 159 SER n 
5 160 TYR n 
5 161 ILE n 
5 162 ASN n 
5 163 ILE n 
5 164 ILE n 
5 165 MET n 
5 166 PRO n 
5 167 SER n 
5 168 VAL n 
5 169 PHE n 
5 170 GLY n 
5 171 THR n 
5 172 ILE n 
5 173 CYS n 
5 174 LEU n 
5 175 LEU n 
5 176 GLY n 
5 177 ILE n 
5 178 ILE n 
5 179 GLY n 
5 180 ASN n 
5 181 SER n 
5 182 THR n 
5 183 VAL n 
5 184 ILE n 
5 185 PHE n 
5 186 ALA n 
5 187 VAL n 
5 188 VAL n 
5 189 LYS n 
5 190 LYS n 
5 191 SER n 
5 192 LYS n 
5 193 LEU n 
5 194 HIS n 
5 195 TRP n 
5 196 CYS n 
5 197 ASN n 
5 198 ASN n 
5 199 VAL n 
5 200 PRO n 
5 201 ASP n 
5 202 ILE n 
5 203 PHE n 
5 204 ILE n 
5 205 ILE n 
5 206 ASN n 
5 207 LEU n 
5 208 SER n 
5 209 VAL n 
5 210 VAL n 
5 211 ASP n 
5 212 LEU n 
5 213 LEU n 
5 214 PHE n 
5 215 LEU n 
5 216 LEU n 
5 217 GLY n 
5 218 MET n 
5 219 PRO n 
5 220 PHE n 
5 221 MET n 
5 222 ILE n 
5 223 HIS n 
5 224 GLN n 
5 225 LEU n 
5 226 MET n 
5 227 GLY n 
5 228 ASN n 
5 229 GLY n 
5 230 VAL n 
5 231 TRP n 
5 232 HIS n 
5 233 PHE n 
5 234 GLY n 
5 235 GLU n 
5 236 THR n 
5 237 MET n 
5 238 CYS n 
5 239 THR n 
5 240 LEU n 
5 241 ILE n 
5 242 THR n 
5 243 ALA n 
5 244 MET n 
5 245 ASP n 
5 246 ALA n 
5 247 ASN n 
5 248 SER n 
5 249 GLN n 
5 250 PHE n 
5 251 THR n 
5 252 SER n 
5 253 THR n 
5 254 TYR n 
5 255 ILE n 
5 256 LEU n 
5 257 THR n 
5 258 ALA n 
5 259 MET n 
5 260 ALA n 
5 261 ILE n 
5 262 ASP n 
5 263 ARG n 
5 264 TYR n 
5 265 LEU n 
5 266 ALA n 
5 267 THR n 
5 268 VAL n 
5 269 HIS n 
5 270 PRO n 
5 271 ILE n 
5 272 SER n 
5 273 SER n 
5 274 THR n 
5 275 LYS n 
5 276 PHE n 
5 277 ARG n 
5 278 LYS n 
5 279 PRO n 
5 280 SER n 
5 281 VAL n 
5 282 ALA n 
5 283 THR n 
5 284 LEU n 
5 285 VAL n 
5 286 ILE n 
5 287 CYS n 
5 288 LEU n 
5 289 LEU n 
5 290 TRP n 
5 291 ALA n 
5 292 LEU n 
5 293 SER n 
5 294 PHE n 
5 295 ILE n 
5 296 SER n 
5 297 ILE n 
5 298 THR n 
5 299 PRO n 
5 300 VAL n 
5 301 TRP n 
5 302 LEU n 
5 303 TYR n 
5 304 ALA n 
5 305 ARG n 
5 306 LEU n 
5 307 ILE n 
5 308 PRO n 
5 309 PHE n 
5 310 PRO n 
5 311 GLY n 
5 312 GLY n 
5 313 ALA n 
5 314 VAL n 
5 315 GLY n 
5 316 CYS n 
5 317 GLY n 
5 318 ILE n 
5 319 ARG n 
5 320 LEU n 
5 321 PRO n 
5 322 ASN n 
5 323 PRO n 
5 324 ASP n 
5 325 THR n 
5 326 ASP n 
5 327 LEU n 
5 328 TYR n 
5 329 TRP n 
5 330 PHE n 
5 331 THR n 
5 332 LEU n 
5 333 TYR n 
5 334 GLN n 
5 335 PHE n 
5 336 PHE n 
5 337 LEU n 
5 338 ALA n 
5 339 PHE n 
5 340 ALA n 
5 341 LEU n 
5 342 PRO n 
5 343 PHE n 
5 344 VAL n 
5 345 VAL n 
5 346 ILE n 
5 347 THR n 
5 348 ALA n 
5 349 ALA n 
5 350 TYR n 
5 351 VAL n 
5 352 ARG n 
5 353 ILE n 
5 354 LEU n 
5 355 GLN n 
5 356 ARG n 
5 357 MET n 
5 358 THR n 
5 359 SER n 
5 360 SER n 
5 361 VAL n 
5 362 ALA n 
5 363 PRO n 
5 364 ALA n 
5 365 SER n 
5 366 GLN n 
5 367 ARG n 
5 368 SER n 
5 369 ILE n 
5 370 ARG n 
5 371 LEU n 
5 372 ARG n 
5 373 THR n 
5 374 LYS n 
5 375 ARG n 
5 376 VAL n 
5 377 THR n 
5 378 ARG n 
5 379 THR n 
5 380 ALA n 
5 381 ILE n 
5 382 ALA n 
5 383 ILE n 
5 384 CYS n 
5 385 LEU n 
5 386 VAL n 
5 387 PHE n 
5 388 PHE n 
5 389 VAL n 
5 390 CYS n 
5 391 TRP n 
5 392 ALA n 
5 393 PRO n 
5 394 TYR n 
5 395 TYR n 
5 396 VAL n 
5 397 LEU n 
5 398 GLN n 
5 399 LEU n 
5 400 THR n 
5 401 GLN n 
5 402 LEU n 
5 403 SER n 
5 404 ILE n 
5 405 SER n 
5 406 ARG n 
5 407 PRO n 
5 408 THR n 
5 409 LEU n 
5 410 THR n 
5 411 PHE n 
5 412 VAL n 
5 413 TYR n 
5 414 LEU n 
5 415 TYR n 
5 416 ASN n 
5 417 ALA n 
5 418 ALA n 
5 419 ILE n 
5 420 SER n 
5 421 LEU n 
5 422 GLY n 
5 423 TYR n 
5 424 ALA n 
5 425 ASN n 
5 426 SER n 
5 427 CYS n 
5 428 LEU n 
5 429 ASN n 
5 430 PRO n 
5 431 PHE n 
5 432 VAL n 
5 433 TYR n 
5 434 ILE n 
5 435 VAL n 
5 436 LEU n 
5 437 CYS n 
5 438 GLU n 
5 439 THR n 
5 440 PHE n 
5 441 ARG n 
5 442 LYS n 
5 443 ARG n 
5 444 LEU n 
5 445 VAL n 
5 446 LEU n 
5 447 SER n 
5 448 VAL n 
5 449 LYS n 
5 450 HIS n 
5 451 MET n 
5 452 GLY n 
5 453 SER n 
5 454 SER n 
5 455 GLY n 
5 456 GLY n 
5 457 GLY n 
5 458 GLY n 
5 459 SER n 
5 460 GLY n 
5 461 GLY n 
5 462 GLY n 
5 463 GLY n 
5 464 SER n 
5 465 SER n 
5 466 GLY n 
5 467 VAL n 
5 468 PHE n 
5 469 THR n 
5 470 LEU n 
5 471 GLU n 
5 472 ASP n 
5 473 PHE n 
5 474 VAL n 
5 475 GLY n 
5 476 ASP n 
5 477 TRP n 
5 478 GLU n 
5 479 GLN n 
5 480 THR n 
5 481 ALA n 
5 482 ALA n 
5 483 TYR n 
5 484 ASN n 
5 485 LEU n 
5 486 ASP n 
5 487 GLN n 
5 488 VAL n 
5 489 LEU n 
5 490 GLU n 
5 491 GLN n 
5 492 GLY n 
5 493 GLY n 
5 494 VAL n 
5 495 SER n 
5 496 SER n 
5 497 LEU n 
5 498 LEU n 
5 499 GLN n 
5 500 ASN n 
5 501 LEU n 
5 502 ALA n 
5 503 VAL n 
5 504 SER n 
5 505 VAL n 
5 506 THR n 
5 507 PRO n 
5 508 ILE n 
5 509 GLN n 
5 510 ARG n 
5 511 ILE n 
5 512 VAL n 
5 513 ARG n 
5 514 SER n 
5 515 GLY n 
5 516 GLU n 
5 517 ASN n 
5 518 ALA n 
5 519 LEU n 
5 520 LYS n 
5 521 ILE n 
5 522 ASP n 
5 523 ILE n 
5 524 HIS n 
5 525 VAL n 
5 526 ILE n 
5 527 ILE n 
5 528 PRO n 
5 529 TYR n 
5 530 GLU n 
5 531 GLY n 
5 532 LEU n 
5 533 SER n 
5 534 ALA n 
5 535 ASP n 
5 536 GLN n 
5 537 MET n 
5 538 ALA n 
5 539 GLN n 
5 540 ILE n 
5 541 GLU n 
5 542 GLU n 
5 543 VAL n 
5 544 PHE n 
5 545 LYS n 
5 546 VAL n 
5 547 VAL n 
5 548 TYR n 
5 549 PRO n 
5 550 VAL n 
5 551 ASP n 
5 552 ASP n 
5 553 HIS n 
5 554 HIS n 
5 555 PHE n 
5 556 LYS n 
5 557 VAL n 
5 558 ILE n 
5 559 LEU n 
5 560 PRO n 
5 561 TYR n 
5 562 GLY n 
5 563 THR n 
5 564 LEU n 
5 565 VAL n 
5 566 ILE n 
5 567 ASP n 
5 568 GLY n 
5 569 VAL n 
5 570 THR n 
5 571 PRO n 
5 572 ASN n 
5 573 MET n 
5 574 LEU n 
5 575 ASN n 
5 576 TYR n 
5 577 PHE n 
5 578 GLY n 
5 579 ARG n 
5 580 PRO n 
5 581 TYR n 
5 582 GLU n 
5 583 GLY n 
5 584 ILE n 
5 585 ALA n 
5 586 VAL n 
5 587 PHE n 
5 588 ASP n 
5 589 GLY n 
5 590 LYS n 
5 591 LYS n 
5 592 ILE n 
5 593 THR n 
5 594 VAL n 
5 595 THR n 
5 596 GLY n 
5 597 THR n 
5 598 LEU n 
5 599 TRP n 
5 600 ASN n 
5 601 GLY n 
5 602 ASN n 
5 603 LYS n 
5 604 ILE n 
5 605 ILE n 
5 606 ASP n 
5 607 GLU n 
5 608 ARG n 
5 609 LEU n 
5 610 ILE n 
5 611 THR n 
5 612 PRO n 
5 613 ASP n 
5 614 GLY n 
5 615 SER n 
5 616 MET n 
5 617 LEU n 
5 618 PHE n 
5 619 ARG n 
5 620 VAL n 
5 621 THR n 
5 622 ILE n 
5 623 ASN n 
5 624 SER n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1   354 human ? GNAI1                ? ? ? ? ? ? 'Homo sapiens'        9606  ? ? ? ? ? ? ? ? 
'Baculovirus expression vector pFastBac1-HM' 274590 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1   376 human ? GNB1                 ? ? ? ? ? ? 'Homo sapiens'        9606  ? ? ? ? ? ? ? ? 
'Baculovirus expression vector pFastBac1-HM' 274590 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1   71  human ? GNG2                 ? ? ? ? ? ? 'Homo sapiens'        9606  ? ? ? ? ? ? ? ? 
'Baculovirus expression vector pFastBac1-HM' 274590 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 'Biological sequence' 1   255 ?     ? ?                    ? ? ? ? ? ? 'synthetic construct' 32630 ? ? ? ? ? ? ? ? 
'Baculovirus expression vector pFastBac1-HM' 274590 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
5 1 sample 'Biological sequence' 1   53  human ? ?                    ? ? ? ? ? ? 'Homo sapiens'        9606  ? ? ? ? ? ? ? ? 
'Baculovirus expression vector pFastBac1-HM' 274590 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
5 2 sample 'Biological sequence' 54  449 human ? 'MCHR1, GPR24, SLC1' ? ? ? ? ? ? 'Homo sapiens'        9606  ? ? ? ? ? ? ? ? 
'Baculovirus expression vector pFastBac1-HM' 274590 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
5 3 sample 'Biological sequence' 450 624 human ? ?                    ? ? ? ? ? ? 'Homo sapiens'        9606  ? ? ? ? ? ? ? ? 
'Baculovirus expression vector pFastBac1-HM' 274590 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   GLY 2   2   ?   ?   ?   A . n 
A 1 3   CYS 3   3   ?   ?   ?   A . n 
A 1 4   THR 4   4   4   THR THR A . n 
A 1 5   LEU 5   5   5   LEU LEU A . n 
A 1 6   SER 6   6   6   SER SER A . n 
A 1 7   ALA 7   7   7   ALA ALA A . n 
A 1 8   GLU 8   8   8   GLU GLU A . n 
A 1 9   ASP 9   9   9   ASP ASP A . n 
A 1 10  LYS 10  10  10  LYS LYS A . n 
A 1 11  ALA 11  11  11  ALA ALA A . n 
A 1 12  ALA 12  12  12  ALA ALA A . n 
A 1 13  VAL 13  13  13  VAL VAL A . n 
A 1 14  GLU 14  14  14  GLU GLU A . n 
A 1 15  ARG 15  15  15  ARG ARG A . n 
A 1 16  SER 16  16  16  SER SER A . n 
A 1 17  LYS 17  17  17  LYS LYS A . n 
A 1 18  MET 18  18  18  MET MET A . n 
A 1 19  ILE 19  19  19  ILE ILE A . n 
A 1 20  ASP 20  20  20  ASP ASP A . n 
A 1 21  ARG 21  21  21  ARG ARG A . n 
A 1 22  ASN 22  22  22  ASN ASN A . n 
A 1 23  LEU 23  23  23  LEU LEU A . n 
A 1 24  ARG 24  24  24  ARG ARG A . n 
A 1 25  GLU 25  25  25  GLU GLU A . n 
A 1 26  ASP 26  26  26  ASP ASP A . n 
A 1 27  GLY 27  27  27  GLY GLY A . n 
A 1 28  GLU 28  28  28  GLU GLU A . n 
A 1 29  LYS 29  29  29  LYS LYS A . n 
A 1 30  ALA 30  30  30  ALA ALA A . n 
A 1 31  ALA 31  31  31  ALA ALA A . n 
A 1 32  ARG 32  32  32  ARG ARG A . n 
A 1 33  GLU 33  33  33  GLU GLU A . n 
A 1 34  VAL 34  34  34  VAL VAL A . n 
A 1 35  LYS 35  35  35  LYS LYS A . n 
A 1 36  LEU 36  36  36  LEU LEU A . n 
A 1 37  LEU 37  37  37  LEU LEU A . n 
A 1 38  LEU 38  38  38  LEU LEU A . n 
A 1 39  LEU 39  39  39  LEU LEU A . n 
A 1 40  GLY 40  40  40  GLY GLY A . n 
A 1 41  ALA 41  41  41  ALA ALA A . n 
A 1 42  GLY 42  42  42  GLY GLY A . n 
A 1 43  GLU 43  43  43  GLU GLU A . n 
A 1 44  SER 44  44  44  SER SER A . n 
A 1 45  GLY 45  45  45  GLY GLY A . n 
A 1 46  LYS 46  46  46  LYS LYS A . n 
A 1 47  ASN 47  47  47  ASN ASN A . n 
A 1 48  THR 48  48  48  THR THR A . n 
A 1 49  ILE 49  49  49  ILE ILE A . n 
A 1 50  VAL 50  50  50  VAL VAL A . n 
A 1 51  LYS 51  51  51  LYS LYS A . n 
A 1 52  GLN 52  52  52  GLN GLN A . n 
A 1 53  MET 53  53  53  MET MET A . n 
A 1 54  LYS 54  54  54  LYS LYS A . n 
A 1 55  ILE 55  55  ?   ?   ?   A . n 
A 1 56  ILE 56  56  ?   ?   ?   A . n 
A 1 57  HIS 57  57  ?   ?   ?   A . n 
A 1 58  GLU 58  58  ?   ?   ?   A . n 
A 1 59  ALA 59  59  ?   ?   ?   A . n 
A 1 60  GLY 60  60  ?   ?   ?   A . n 
A 1 61  TYR 61  61  ?   ?   ?   A . n 
A 1 62  SER 62  62  ?   ?   ?   A . n 
A 1 63  GLU 63  63  ?   ?   ?   A . n 
A 1 64  GLU 64  64  ?   ?   ?   A . n 
A 1 65  GLU 65  65  ?   ?   ?   A . n 
A 1 66  CYS 66  66  ?   ?   ?   A . n 
A 1 67  LYS 67  67  ?   ?   ?   A . n 
A 1 68  GLN 68  68  ?   ?   ?   A . n 
A 1 69  TYR 69  69  ?   ?   ?   A . n 
A 1 70  LYS 70  70  ?   ?   ?   A . n 
A 1 71  ALA 71  71  ?   ?   ?   A . n 
A 1 72  VAL 72  72  ?   ?   ?   A . n 
A 1 73  VAL 73  73  ?   ?   ?   A . n 
A 1 74  TYR 74  74  ?   ?   ?   A . n 
A 1 75  SER 75  75  ?   ?   ?   A . n 
A 1 76  ASN 76  76  ?   ?   ?   A . n 
A 1 77  THR 77  77  ?   ?   ?   A . n 
A 1 78  ILE 78  78  ?   ?   ?   A . n 
A 1 79  GLN 79  79  ?   ?   ?   A . n 
A 1 80  SER 80  80  ?   ?   ?   A . n 
A 1 81  ILE 81  81  ?   ?   ?   A . n 
A 1 82  ILE 82  82  ?   ?   ?   A . n 
A 1 83  ALA 83  83  ?   ?   ?   A . n 
A 1 84  ILE 84  84  ?   ?   ?   A . n 
A 1 85  ILE 85  85  ?   ?   ?   A . n 
A 1 86  ARG 86  86  ?   ?   ?   A . n 
A 1 87  ALA 87  87  ?   ?   ?   A . n 
A 1 88  MET 88  88  ?   ?   ?   A . n 
A 1 89  GLY 89  89  ?   ?   ?   A . n 
A 1 90  ARG 90  90  ?   ?   ?   A . n 
A 1 91  LEU 91  91  ?   ?   ?   A . n 
A 1 92  LYS 92  92  ?   ?   ?   A . n 
A 1 93  ILE 93  93  ?   ?   ?   A . n 
A 1 94  ASP 94  94  ?   ?   ?   A . n 
A 1 95  PHE 95  95  ?   ?   ?   A . n 
A 1 96  GLY 96  96  ?   ?   ?   A . n 
A 1 97  ASP 97  97  ?   ?   ?   A . n 
A 1 98  SER 98  98  ?   ?   ?   A . n 
A 1 99  ALA 99  99  ?   ?   ?   A . n 
A 1 100 ARG 100 100 ?   ?   ?   A . n 
A 1 101 ALA 101 101 ?   ?   ?   A . n 
A 1 102 ASP 102 102 ?   ?   ?   A . n 
A 1 103 ASP 103 103 ?   ?   ?   A . n 
A 1 104 ALA 104 104 ?   ?   ?   A . n 
A 1 105 ARG 105 105 ?   ?   ?   A . n 
A 1 106 GLN 106 106 ?   ?   ?   A . n 
A 1 107 LEU 107 107 ?   ?   ?   A . n 
A 1 108 PHE 108 108 ?   ?   ?   A . n 
A 1 109 VAL 109 109 ?   ?   ?   A . n 
A 1 110 LEU 110 110 ?   ?   ?   A . n 
A 1 111 ALA 111 111 ?   ?   ?   A . n 
A 1 112 GLY 112 112 ?   ?   ?   A . n 
A 1 113 ALA 113 113 ?   ?   ?   A . n 
A 1 114 ALA 114 114 ?   ?   ?   A . n 
A 1 115 GLU 115 115 ?   ?   ?   A . n 
A 1 116 GLU 116 116 ?   ?   ?   A . n 
A 1 117 GLY 117 117 ?   ?   ?   A . n 
A 1 118 PHE 118 118 ?   ?   ?   A . n 
A 1 119 MET 119 119 ?   ?   ?   A . n 
A 1 120 THR 120 120 ?   ?   ?   A . n 
A 1 121 ALA 121 121 ?   ?   ?   A . n 
A 1 122 GLU 122 122 ?   ?   ?   A . n 
A 1 123 LEU 123 123 ?   ?   ?   A . n 
A 1 124 ALA 124 124 ?   ?   ?   A . n 
A 1 125 GLY 125 125 ?   ?   ?   A . n 
A 1 126 VAL 126 126 ?   ?   ?   A . n 
A 1 127 ILE 127 127 ?   ?   ?   A . n 
A 1 128 LYS 128 128 ?   ?   ?   A . n 
A 1 129 ARG 129 129 ?   ?   ?   A . n 
A 1 130 LEU 130 130 ?   ?   ?   A . n 
A 1 131 TRP 131 131 ?   ?   ?   A . n 
A 1 132 LYS 132 132 ?   ?   ?   A . n 
A 1 133 ASP 133 133 ?   ?   ?   A . n 
A 1 134 SER 134 134 ?   ?   ?   A . n 
A 1 135 GLY 135 135 ?   ?   ?   A . n 
A 1 136 VAL 136 136 ?   ?   ?   A . n 
A 1 137 GLN 137 137 ?   ?   ?   A . n 
A 1 138 ALA 138 138 ?   ?   ?   A . n 
A 1 139 CYS 139 139 ?   ?   ?   A . n 
A 1 140 PHE 140 140 ?   ?   ?   A . n 
A 1 141 ASN 141 141 ?   ?   ?   A . n 
A 1 142 ARG 142 142 ?   ?   ?   A . n 
A 1 143 SER 143 143 ?   ?   ?   A . n 
A 1 144 ARG 144 144 ?   ?   ?   A . n 
A 1 145 GLU 145 145 ?   ?   ?   A . n 
A 1 146 TYR 146 146 ?   ?   ?   A . n 
A 1 147 GLN 147 147 ?   ?   ?   A . n 
A 1 148 LEU 148 148 ?   ?   ?   A . n 
A 1 149 ASN 149 149 ?   ?   ?   A . n 
A 1 150 ASP 150 150 ?   ?   ?   A . n 
A 1 151 SER 151 151 ?   ?   ?   A . n 
A 1 152 ALA 152 152 ?   ?   ?   A . n 
A 1 153 ALA 153 153 ?   ?   ?   A . n 
A 1 154 TYR 154 154 ?   ?   ?   A . n 
A 1 155 TYR 155 155 ?   ?   ?   A . n 
A 1 156 LEU 156 156 ?   ?   ?   A . n 
A 1 157 ASN 157 157 ?   ?   ?   A . n 
A 1 158 ASP 158 158 ?   ?   ?   A . n 
A 1 159 LEU 159 159 ?   ?   ?   A . n 
A 1 160 ASP 160 160 ?   ?   ?   A . n 
A 1 161 ARG 161 161 ?   ?   ?   A . n 
A 1 162 ILE 162 162 ?   ?   ?   A . n 
A 1 163 ALA 163 163 ?   ?   ?   A . n 
A 1 164 GLN 164 164 ?   ?   ?   A . n 
A 1 165 PRO 165 165 ?   ?   ?   A . n 
A 1 166 ASN 166 166 ?   ?   ?   A . n 
A 1 167 TYR 167 167 ?   ?   ?   A . n 
A 1 168 ILE 168 168 ?   ?   ?   A . n 
A 1 169 PRO 169 169 ?   ?   ?   A . n 
A 1 170 THR 170 170 ?   ?   ?   A . n 
A 1 171 GLN 171 171 ?   ?   ?   A . n 
A 1 172 GLN 172 172 ?   ?   ?   A . n 
A 1 173 ASP 173 173 ?   ?   ?   A . n 
A 1 174 VAL 174 174 ?   ?   ?   A . n 
A 1 175 LEU 175 175 ?   ?   ?   A . n 
A 1 176 ARG 176 176 ?   ?   ?   A . n 
A 1 177 THR 177 177 ?   ?   ?   A . n 
A 1 178 ARG 178 178 ?   ?   ?   A . n 
A 1 179 VAL 179 179 ?   ?   ?   A . n 
A 1 180 LYS 180 180 ?   ?   ?   A . n 
A 1 181 THR 181 181 ?   ?   ?   A . n 
A 1 182 THR 182 182 182 THR THR A . n 
A 1 183 GLY 183 183 183 GLY GLY A . n 
A 1 184 ILE 184 184 184 ILE ILE A . n 
A 1 185 VAL 185 185 185 VAL VAL A . n 
A 1 186 GLU 186 186 186 GLU GLU A . n 
A 1 187 THR 187 187 187 THR THR A . n 
A 1 188 HIS 188 188 188 HIS HIS A . n 
A 1 189 PHE 189 189 189 PHE PHE A . n 
A 1 190 THR 190 190 190 THR THR A . n 
A 1 191 PHE 191 191 191 PHE PHE A . n 
A 1 192 LYS 192 192 192 LYS LYS A . n 
A 1 193 ASP 193 193 193 ASP ASP A . n 
A 1 194 LEU 194 194 194 LEU LEU A . n 
A 1 195 HIS 195 195 195 HIS HIS A . n 
A 1 196 PHE 196 196 196 PHE PHE A . n 
A 1 197 LYS 197 197 197 LYS LYS A . n 
A 1 198 MET 198 198 198 MET MET A . n 
A 1 199 PHE 199 199 199 PHE PHE A . n 
A 1 200 ASP 200 200 200 ASP ASP A . n 
A 1 201 VAL 201 201 201 VAL VAL A . n 
A 1 202 GLY 202 202 202 GLY GLY A . n 
A 1 203 ALA 203 203 203 ALA ALA A . n 
A 1 204 GLN 204 204 204 GLN GLN A . n 
A 1 205 ARG 205 205 205 ARG ARG A . n 
A 1 206 SER 206 206 206 SER SER A . n 
A 1 207 GLU 207 207 207 GLU GLU A . n 
A 1 208 ARG 208 208 208 ARG ARG A . n 
A 1 209 LYS 209 209 209 LYS LYS A . n 
A 1 210 LYS 210 210 210 LYS LYS A . n 
A 1 211 TRP 211 211 211 TRP TRP A . n 
A 1 212 ILE 212 212 212 ILE ILE A . n 
A 1 213 HIS 213 213 213 HIS HIS A . n 
A 1 214 CYS 214 214 214 CYS CYS A . n 
A 1 215 PHE 215 215 215 PHE PHE A . n 
A 1 216 GLU 216 216 216 GLU GLU A . n 
A 1 217 GLY 217 217 217 GLY GLY A . n 
A 1 218 VAL 218 218 218 VAL VAL A . n 
A 1 219 THR 219 219 219 THR THR A . n 
A 1 220 ALA 220 220 220 ALA ALA A . n 
A 1 221 ILE 221 221 221 ILE ILE A . n 
A 1 222 ILE 222 222 222 ILE ILE A . n 
A 1 223 PHE 223 223 223 PHE PHE A . n 
A 1 224 CYS 224 224 224 CYS CYS A . n 
A 1 225 VAL 225 225 225 VAL VAL A . n 
A 1 226 ALA 226 226 226 ALA ALA A . n 
A 1 227 LEU 227 227 227 LEU LEU A . n 
A 1 228 SER 228 228 228 SER SER A . n 
A 1 229 ASP 229 229 229 ASP ASP A . n 
A 1 230 TYR 230 230 230 TYR TYR A . n 
A 1 231 ASP 231 231 231 ASP ASP A . n 
A 1 232 LEU 232 232 232 LEU LEU A . n 
A 1 233 VAL 233 233 233 VAL VAL A . n 
A 1 234 LEU 234 234 234 LEU LEU A . n 
A 1 235 ALA 235 235 235 ALA ALA A . n 
A 1 236 GLU 236 236 236 GLU GLU A . n 
A 1 237 ASP 237 237 237 ASP ASP A . n 
A 1 238 GLU 238 238 238 GLU GLU A . n 
A 1 239 GLU 239 239 239 GLU GLU A . n 
A 1 240 MET 240 240 240 MET MET A . n 
A 1 241 ASN 241 241 241 ASN ASN A . n 
A 1 242 ARG 242 242 242 ARG ARG A . n 
A 1 243 MET 243 243 243 MET MET A . n 
A 1 244 HIS 244 244 244 HIS HIS A . n 
A 1 245 ALA 245 245 245 ALA ALA A . n 
A 1 246 SER 246 246 246 SER SER A . n 
A 1 247 MET 247 247 247 MET MET A . n 
A 1 248 LYS 248 248 248 LYS LYS A . n 
A 1 249 LEU 249 249 249 LEU LEU A . n 
A 1 250 PHE 250 250 250 PHE PHE A . n 
A 1 251 ASP 251 251 251 ASP ASP A . n 
A 1 252 SER 252 252 252 SER SER A . n 
A 1 253 ILE 253 253 253 ILE ILE A . n 
A 1 254 CYS 254 254 254 CYS CYS A . n 
A 1 255 ASN 255 255 255 ASN ASN A . n 
A 1 256 ASN 256 256 256 ASN ASN A . n 
A 1 257 LYS 257 257 257 LYS LYS A . n 
A 1 258 TRP 258 258 258 TRP TRP A . n 
A 1 259 PHE 259 259 259 PHE PHE A . n 
A 1 260 THR 260 260 260 THR THR A . n 
A 1 261 ASP 261 261 261 ASP ASP A . n 
A 1 262 THR 262 262 262 THR THR A . n 
A 1 263 SER 263 263 263 SER SER A . n 
A 1 264 ILE 264 264 264 ILE ILE A . n 
A 1 265 ILE 265 265 265 ILE ILE A . n 
A 1 266 LEU 266 266 266 LEU LEU A . n 
A 1 267 PHE 267 267 267 PHE PHE A . n 
A 1 268 LEU 268 268 268 LEU LEU A . n 
A 1 269 ASN 269 269 269 ASN ASN A . n 
A 1 270 LYS 270 270 270 LYS LYS A . n 
A 1 271 LYS 271 271 271 LYS LYS A . n 
A 1 272 ASP 272 272 272 ASP ASP A . n 
A 1 273 LEU 273 273 273 LEU LEU A . n 
A 1 274 PHE 274 274 274 PHE PHE A . n 
A 1 275 GLU 275 275 275 GLU GLU A . n 
A 1 276 GLU 276 276 276 GLU GLU A . n 
A 1 277 LYS 277 277 277 LYS LYS A . n 
A 1 278 ILE 278 278 278 ILE ILE A . n 
A 1 279 LYS 279 279 279 LYS LYS A . n 
A 1 280 LYS 280 280 280 LYS LYS A . n 
A 1 281 SER 281 281 281 SER SER A . n 
A 1 282 PRO 282 282 282 PRO PRO A . n 
A 1 283 LEU 283 283 283 LEU LEU A . n 
A 1 284 THR 284 284 284 THR THR A . n 
A 1 285 ILE 285 285 285 ILE ILE A . n 
A 1 286 CYS 286 286 286 CYS CYS A . n 
A 1 287 TYR 287 287 287 TYR TYR A . n 
A 1 288 PRO 288 288 288 PRO PRO A . n 
A 1 289 GLU 289 289 289 GLU GLU A . n 
A 1 290 TYR 290 290 290 TYR TYR A . n 
A 1 291 ALA 291 291 291 ALA ALA A . n 
A 1 292 GLY 292 292 292 GLY GLY A . n 
A 1 293 SER 293 293 293 SER SER A . n 
A 1 294 ASN 294 294 294 ASN ASN A . n 
A 1 295 THR 295 295 295 THR THR A . n 
A 1 296 TYR 296 296 296 TYR TYR A . n 
A 1 297 GLU 297 297 297 GLU GLU A . n 
A 1 298 GLU 298 298 298 GLU GLU A . n 
A 1 299 ALA 299 299 299 ALA ALA A . n 
A 1 300 ALA 300 300 300 ALA ALA A . n 
A 1 301 ALA 301 301 301 ALA ALA A . n 
A 1 302 TYR 302 302 302 TYR TYR A . n 
A 1 303 ILE 303 303 303 ILE ILE A . n 
A 1 304 GLN 304 304 304 GLN GLN A . n 
A 1 305 CYS 305 305 305 CYS CYS A . n 
A 1 306 GLN 306 306 306 GLN GLN A . n 
A 1 307 PHE 307 307 307 PHE PHE A . n 
A 1 308 GLU 308 308 308 GLU GLU A . n 
A 1 309 ASP 309 309 309 ASP ASP A . n 
A 1 310 LEU 310 310 310 LEU LEU A . n 
A 1 311 ASN 311 311 311 ASN ASN A . n 
A 1 312 LYS 312 312 312 LYS LYS A . n 
A 1 313 ARG 313 313 313 ARG ARG A . n 
A 1 314 LYS 314 314 314 LYS LYS A . n 
A 1 315 ASP 315 315 315 ASP ASP A . n 
A 1 316 THR 316 316 316 THR THR A . n 
A 1 317 LYS 317 317 317 LYS LYS A . n 
A 1 318 GLU 318 318 318 GLU GLU A . n 
A 1 319 ILE 319 319 319 ILE ILE A . n 
A 1 320 TYR 320 320 320 TYR TYR A . n 
A 1 321 THR 321 321 321 THR THR A . n 
A 1 322 HIS 322 322 322 HIS HIS A . n 
A 1 323 PHE 323 323 323 PHE PHE A . n 
A 1 324 THR 324 324 324 THR THR A . n 
A 1 325 CYS 325 325 325 CYS CYS A . n 
A 1 326 SER 326 326 326 SER SER A . n 
A 1 327 THR 327 327 327 THR THR A . n 
A 1 328 ASP 328 328 328 ASP ASP A . n 
A 1 329 THR 329 329 329 THR THR A . n 
A 1 330 LYS 330 330 330 LYS LYS A . n 
A 1 331 ASN 331 331 331 ASN ASN A . n 
A 1 332 VAL 332 332 332 VAL VAL A . n 
A 1 333 GLN 333 333 333 GLN GLN A . n 
A 1 334 PHE 334 334 334 PHE PHE A . n 
A 1 335 VAL 335 335 335 VAL VAL A . n 
A 1 336 PHE 336 336 336 PHE PHE A . n 
A 1 337 ASP 337 337 337 ASP ASP A . n 
A 1 338 ALA 338 338 338 ALA ALA A . n 
A 1 339 VAL 339 339 339 VAL VAL A . n 
A 1 340 THR 340 340 340 THR THR A . n 
A 1 341 ASP 341 341 341 ASP ASP A . n 
A 1 342 VAL 342 342 342 VAL VAL A . n 
A 1 343 ILE 343 343 343 ILE ILE A . n 
A 1 344 ILE 344 344 344 ILE ILE A . n 
A 1 345 LYS 345 345 345 LYS LYS A . n 
A 1 346 ASN 346 346 346 ASN ASN A . n 
A 1 347 ASN 347 347 347 ASN ASN A . n 
A 1 348 LEU 348 348 348 LEU LEU A . n 
A 1 349 LYS 349 349 349 LYS LYS A . n 
A 1 350 ASP 350 350 350 ASP ASP A . n 
A 1 351 CYS 351 351 351 CYS CYS A . n 
A 1 352 GLY 352 352 352 GLY GLY A . n 
A 1 353 LEU 353 353 353 LEU LEU A . n 
A 1 354 PHE 354 354 354 PHE PHE A . n 
B 2 1   MET 1   -9  ?   ?   ?   B . n 
B 2 2   HIS 2   -8  ?   ?   ?   B . n 
B 2 3   HIS 3   -7  ?   ?   ?   B . n 
B 2 4   HIS 4   -6  ?   ?   ?   B . n 
B 2 5   HIS 5   -5  ?   ?   ?   B . n 
B 2 6   HIS 6   -4  ?   ?   ?   B . n 
B 2 7   HIS 7   -3  ?   ?   ?   B . n 
B 2 8   GLY 8   -2  ?   ?   ?   B . n 
B 2 9   SER 9   -1  ?   ?   ?   B . n 
B 2 10  SER 10  0   ?   ?   ?   B . n 
B 2 11  GLY 11  1   ?   ?   ?   B . n 
B 2 12  SER 12  2   2   SER SER B . n 
B 2 13  GLU 13  3   3   GLU GLU B . n 
B 2 14  LEU 14  4   4   LEU LEU B . n 
B 2 15  ASP 15  5   5   ASP ASP B . n 
B 2 16  GLN 16  6   6   GLN GLN B . n 
B 2 17  LEU 17  7   7   LEU LEU B . n 
B 2 18  ARG 18  8   8   ARG ARG B . n 
B 2 19  GLN 19  9   9   GLN GLN B . n 
B 2 20  GLU 20  10  10  GLU GLU B . n 
B 2 21  ALA 21  11  11  ALA ALA B . n 
B 2 22  GLU 22  12  12  GLU GLU B . n 
B 2 23  GLN 23  13  13  GLN GLN B . n 
B 2 24  LEU 24  14  14  LEU LEU B . n 
B 2 25  LYS 25  15  15  LYS LYS B . n 
B 2 26  ASN 26  16  16  ASN ASN B . n 
B 2 27  GLN 27  17  17  GLN GLN B . n 
B 2 28  ILE 28  18  18  ILE ILE B . n 
B 2 29  ARG 29  19  19  ARG ARG B . n 
B 2 30  ASP 30  20  20  ASP ASP B . n 
B 2 31  ALA 31  21  21  ALA ALA B . n 
B 2 32  ARG 32  22  22  ARG ARG B . n 
B 2 33  LYS 33  23  23  LYS LYS B . n 
B 2 34  ALA 34  24  24  ALA ALA B . n 
B 2 35  CYS 35  25  25  CYS CYS B . n 
B 2 36  ALA 36  26  26  ALA ALA B . n 
B 2 37  ASP 37  27  27  ASP ASP B . n 
B 2 38  ALA 38  28  28  ALA ALA B . n 
B 2 39  THR 39  29  29  THR THR B . n 
B 2 40  LEU 40  30  30  LEU LEU B . n 
B 2 41  SER 41  31  31  SER SER B . n 
B 2 42  GLN 42  32  32  GLN GLN B . n 
B 2 43  ILE 43  33  33  ILE ILE B . n 
B 2 44  THR 44  34  34  THR THR B . n 
B 2 45  ASN 45  35  35  ASN ASN B . n 
B 2 46  ASN 46  36  36  ASN ASN B . n 
B 2 47  ILE 47  37  37  ILE ILE B . n 
B 2 48  ASP 48  38  38  ASP ASP B . n 
B 2 49  PRO 49  39  39  PRO PRO B . n 
B 2 50  VAL 50  40  40  VAL VAL B . n 
B 2 51  GLY 51  41  41  GLY GLY B . n 
B 2 52  ARG 52  42  42  ARG ARG B . n 
B 2 53  ILE 53  43  43  ILE ILE B . n 
B 2 54  GLN 54  44  44  GLN GLN B . n 
B 2 55  MET 55  45  45  MET MET B . n 
B 2 56  ARG 56  46  46  ARG ARG B . n 
B 2 57  THR 57  47  47  THR THR B . n 
B 2 58  ARG 58  48  48  ARG ARG B . n 
B 2 59  ARG 59  49  49  ARG ARG B . n 
B 2 60  THR 60  50  50  THR THR B . n 
B 2 61  LEU 61  51  51  LEU LEU B . n 
B 2 62  ARG 62  52  52  ARG ARG B . n 
B 2 63  GLY 63  53  53  GLY GLY B . n 
B 2 64  HIS 64  54  54  HIS HIS B . n 
B 2 65  LEU 65  55  55  LEU LEU B . n 
B 2 66  ALA 66  56  56  ALA ALA B . n 
B 2 67  LYS 67  57  57  LYS LYS B . n 
B 2 68  ILE 68  58  58  ILE ILE B . n 
B 2 69  TYR 69  59  59  TYR TYR B . n 
B 2 70  ALA 70  60  60  ALA ALA B . n 
B 2 71  MET 71  61  61  MET MET B . n 
B 2 72  HIS 72  62  62  HIS HIS B . n 
B 2 73  TRP 73  63  63  TRP TRP B . n 
B 2 74  GLY 74  64  64  GLY GLY B . n 
B 2 75  THR 75  65  65  THR THR B . n 
B 2 76  ASP 76  66  66  ASP ASP B . n 
B 2 77  SER 77  67  67  SER SER B . n 
B 2 78  ARG 78  68  68  ARG ARG B . n 
B 2 79  LEU 79  69  69  LEU LEU B . n 
B 2 80  LEU 80  70  70  LEU LEU B . n 
B 2 81  VAL 81  71  71  VAL VAL B . n 
B 2 82  SER 82  72  72  SER SER B . n 
B 2 83  ALA 83  73  73  ALA ALA B . n 
B 2 84  SER 84  74  74  SER SER B . n 
B 2 85  GLN 85  75  75  GLN GLN B . n 
B 2 86  ASP 86  76  76  ASP ASP B . n 
B 2 87  GLY 87  77  77  GLY GLY B . n 
B 2 88  LYS 88  78  78  LYS LYS B . n 
B 2 89  LEU 89  79  79  LEU LEU B . n 
B 2 90  ILE 90  80  80  ILE ILE B . n 
B 2 91  ILE 91  81  81  ILE ILE B . n 
B 2 92  TRP 92  82  82  TRP TRP B . n 
B 2 93  ASP 93  83  83  ASP ASP B . n 
B 2 94  SER 94  84  84  SER SER B . n 
B 2 95  TYR 95  85  85  TYR TYR B . n 
B 2 96  THR 96  86  86  THR THR B . n 
B 2 97  THR 97  87  87  THR THR B . n 
B 2 98  ASN 98  88  88  ASN ASN B . n 
B 2 99  LYS 99  89  89  LYS LYS B . n 
B 2 100 VAL 100 90  90  VAL VAL B . n 
B 2 101 HIS 101 91  91  HIS HIS B . n 
B 2 102 ALA 102 92  92  ALA ALA B . n 
B 2 103 ILE 103 93  93  ILE ILE B . n 
B 2 104 PRO 104 94  94  PRO PRO B . n 
B 2 105 LEU 105 95  95  LEU LEU B . n 
B 2 106 ARG 106 96  96  ARG ARG B . n 
B 2 107 SER 107 97  97  SER SER B . n 
B 2 108 SER 108 98  98  SER SER B . n 
B 2 109 TRP 109 99  99  TRP TRP B . n 
B 2 110 VAL 110 100 100 VAL VAL B . n 
B 2 111 MET 111 101 101 MET MET B . n 
B 2 112 THR 112 102 102 THR THR B . n 
B 2 113 CYS 113 103 103 CYS CYS B . n 
B 2 114 ALA 114 104 104 ALA ALA B . n 
B 2 115 TYR 115 105 105 TYR TYR B . n 
B 2 116 ALA 116 106 106 ALA ALA B . n 
B 2 117 PRO 117 107 107 PRO PRO B . n 
B 2 118 SER 118 108 108 SER SER B . n 
B 2 119 GLY 119 109 109 GLY GLY B . n 
B 2 120 ASN 120 110 110 ASN ASN B . n 
B 2 121 TYR 121 111 111 TYR TYR B . n 
B 2 122 VAL 122 112 112 VAL VAL B . n 
B 2 123 ALA 123 113 113 ALA ALA B . n 
B 2 124 CYS 124 114 114 CYS CYS B . n 
B 2 125 GLY 125 115 115 GLY GLY B . n 
B 2 126 GLY 126 116 116 GLY GLY B . n 
B 2 127 LEU 127 117 117 LEU LEU B . n 
B 2 128 ASP 128 118 118 ASP ASP B . n 
B 2 129 ASN 129 119 119 ASN ASN B . n 
B 2 130 ILE 130 120 120 ILE ILE B . n 
B 2 131 CYS 131 121 121 CYS CYS B . n 
B 2 132 SER 132 122 122 SER SER B . n 
B 2 133 ILE 133 123 123 ILE ILE B . n 
B 2 134 TYR 134 124 124 TYR TYR B . n 
B 2 135 ASN 135 125 125 ASN ASN B . n 
B 2 136 LEU 136 126 126 LEU LEU B . n 
B 2 137 LYS 137 127 127 LYS LYS B . n 
B 2 138 THR 138 128 128 THR THR B . n 
B 2 139 ARG 139 129 129 ARG ARG B . n 
B 2 140 GLU 140 130 130 GLU GLU B . n 
B 2 141 GLY 141 131 131 GLY GLY B . n 
B 2 142 ASN 142 132 132 ASN ASN B . n 
B 2 143 VAL 143 133 133 VAL VAL B . n 
B 2 144 ARG 144 134 134 ARG ARG B . n 
B 2 145 VAL 145 135 135 VAL VAL B . n 
B 2 146 SER 146 136 136 SER SER B . n 
B 2 147 ARG 147 137 137 ARG ARG B . n 
B 2 148 GLU 148 138 138 GLU GLU B . n 
B 2 149 LEU 149 139 139 LEU LEU B . n 
B 2 150 ALA 150 140 140 ALA ALA B . n 
B 2 151 GLY 151 141 141 GLY GLY B . n 
B 2 152 HIS 152 142 142 HIS HIS B . n 
B 2 153 THR 153 143 143 THR THR B . n 
B 2 154 GLY 154 144 144 GLY GLY B . n 
B 2 155 TYR 155 145 145 TYR TYR B . n 
B 2 156 LEU 156 146 146 LEU LEU B . n 
B 2 157 SER 157 147 147 SER SER B . n 
B 2 158 CYS 158 148 148 CYS CYS B . n 
B 2 159 CYS 159 149 149 CYS CYS B . n 
B 2 160 ARG 160 150 150 ARG ARG B . n 
B 2 161 PHE 161 151 151 PHE PHE B . n 
B 2 162 LEU 162 152 152 LEU LEU B . n 
B 2 163 ASP 163 153 153 ASP ASP B . n 
B 2 164 ASP 164 154 154 ASP ASP B . n 
B 2 165 ASN 165 155 155 ASN ASN B . n 
B 2 166 GLN 166 156 156 GLN GLN B . n 
B 2 167 ILE 167 157 157 ILE ILE B . n 
B 2 168 VAL 168 158 158 VAL VAL B . n 
B 2 169 THR 169 159 159 THR THR B . n 
B 2 170 SER 170 160 160 SER SER B . n 
B 2 171 SER 171 161 161 SER SER B . n 
B 2 172 GLY 172 162 162 GLY GLY B . n 
B 2 173 ASP 173 163 163 ASP ASP B . n 
B 2 174 THR 174 164 164 THR THR B . n 
B 2 175 THR 175 165 165 THR THR B . n 
B 2 176 CYS 176 166 166 CYS CYS B . n 
B 2 177 ALA 177 167 167 ALA ALA B . n 
B 2 178 LEU 178 168 168 LEU LEU B . n 
B 2 179 TRP 179 169 169 TRP TRP B . n 
B 2 180 ASP 180 170 170 ASP ASP B . n 
B 2 181 ILE 181 171 171 ILE ILE B . n 
B 2 182 GLU 182 172 172 GLU GLU B . n 
B 2 183 THR 183 173 173 THR THR B . n 
B 2 184 GLY 184 174 174 GLY GLY B . n 
B 2 185 GLN 185 175 175 GLN GLN B . n 
B 2 186 GLN 186 176 176 GLN GLN B . n 
B 2 187 THR 187 177 177 THR THR B . n 
B 2 188 THR 188 178 178 THR THR B . n 
B 2 189 THR 189 179 179 THR THR B . n 
B 2 190 PHE 190 180 180 PHE PHE B . n 
B 2 191 THR 191 181 181 THR THR B . n 
B 2 192 GLY 192 182 182 GLY GLY B . n 
B 2 193 HIS 193 183 183 HIS HIS B . n 
B 2 194 THR 194 184 184 THR THR B . n 
B 2 195 GLY 195 185 185 GLY GLY B . n 
B 2 196 ASP 196 186 186 ASP ASP B . n 
B 2 197 VAL 197 187 187 VAL VAL B . n 
B 2 198 MET 198 188 188 MET MET B . n 
B 2 199 SER 199 189 189 SER SER B . n 
B 2 200 LEU 200 190 190 LEU LEU B . n 
B 2 201 SER 201 191 191 SER SER B . n 
B 2 202 LEU 202 192 192 LEU LEU B . n 
B 2 203 ALA 203 193 193 ALA ALA B . n 
B 2 204 PRO 204 194 194 PRO PRO B . n 
B 2 205 ASP 205 195 195 ASP ASP B . n 
B 2 206 THR 206 196 196 THR THR B . n 
B 2 207 ARG 207 197 197 ARG ARG B . n 
B 2 208 LEU 208 198 198 LEU LEU B . n 
B 2 209 PHE 209 199 199 PHE PHE B . n 
B 2 210 VAL 210 200 200 VAL VAL B . n 
B 2 211 SER 211 201 201 SER SER B . n 
B 2 212 GLY 212 202 202 GLY GLY B . n 
B 2 213 ALA 213 203 203 ALA ALA B . n 
B 2 214 CYS 214 204 204 CYS CYS B . n 
B 2 215 ASP 215 205 205 ASP ASP B . n 
B 2 216 ALA 216 206 206 ALA ALA B . n 
B 2 217 SER 217 207 207 SER SER B . n 
B 2 218 ALA 218 208 208 ALA ALA B . n 
B 2 219 LYS 219 209 209 LYS LYS B . n 
B 2 220 LEU 220 210 210 LEU LEU B . n 
B 2 221 TRP 221 211 211 TRP TRP B . n 
B 2 222 ASP 222 212 212 ASP ASP B . n 
B 2 223 VAL 223 213 213 VAL VAL B . n 
B 2 224 ARG 224 214 214 ARG ARG B . n 
B 2 225 GLU 225 215 215 GLU GLU B . n 
B 2 226 GLY 226 216 216 GLY GLY B . n 
B 2 227 MET 227 217 217 MET MET B . n 
B 2 228 CYS 228 218 218 CYS CYS B . n 
B 2 229 ARG 229 219 219 ARG ARG B . n 
B 2 230 GLN 230 220 220 GLN GLN B . n 
B 2 231 THR 231 221 221 THR THR B . n 
B 2 232 PHE 232 222 222 PHE PHE B . n 
B 2 233 THR 233 223 223 THR THR B . n 
B 2 234 GLY 234 224 224 GLY GLY B . n 
B 2 235 HIS 235 225 225 HIS HIS B . n 
B 2 236 GLU 236 226 226 GLU GLU B . n 
B 2 237 SER 237 227 227 SER SER B . n 
B 2 238 ASP 238 228 228 ASP ASP B . n 
B 2 239 ILE 239 229 229 ILE ILE B . n 
B 2 240 ASN 240 230 230 ASN ASN B . n 
B 2 241 ALA 241 231 231 ALA ALA B . n 
B 2 242 ILE 242 232 232 ILE ILE B . n 
B 2 243 CYS 243 233 233 CYS CYS B . n 
B 2 244 PHE 244 234 234 PHE PHE B . n 
B 2 245 PHE 245 235 235 PHE PHE B . n 
B 2 246 PRO 246 236 236 PRO PRO B . n 
B 2 247 ASN 247 237 237 ASN ASN B . n 
B 2 248 GLY 248 238 238 GLY GLY B . n 
B 2 249 ASN 249 239 239 ASN ASN B . n 
B 2 250 ALA 250 240 240 ALA ALA B . n 
B 2 251 PHE 251 241 241 PHE PHE B . n 
B 2 252 ALA 252 242 242 ALA ALA B . n 
B 2 253 THR 253 243 243 THR THR B . n 
B 2 254 GLY 254 244 244 GLY GLY B . n 
B 2 255 SER 255 245 245 SER SER B . n 
B 2 256 ASP 256 246 246 ASP ASP B . n 
B 2 257 ASP 257 247 247 ASP ASP B . n 
B 2 258 ALA 258 248 248 ALA ALA B . n 
B 2 259 THR 259 249 249 THR THR B . n 
B 2 260 CYS 260 250 250 CYS CYS B . n 
B 2 261 ARG 261 251 251 ARG ARG B . n 
B 2 262 LEU 262 252 252 LEU LEU B . n 
B 2 263 PHE 263 253 253 PHE PHE B . n 
B 2 264 ASP 264 254 254 ASP ASP B . n 
B 2 265 LEU 265 255 255 LEU LEU B . n 
B 2 266 ARG 266 256 256 ARG ARG B . n 
B 2 267 ALA 267 257 257 ALA ALA B . n 
B 2 268 ASP 268 258 258 ASP ASP B . n 
B 2 269 GLN 269 259 259 GLN GLN B . n 
B 2 270 GLU 270 260 260 GLU GLU B . n 
B 2 271 LEU 271 261 261 LEU LEU B . n 
B 2 272 MET 272 262 262 MET MET B . n 
B 2 273 THR 273 263 263 THR THR B . n 
B 2 274 TYR 274 264 264 TYR TYR B . n 
B 2 275 SER 275 265 265 SER SER B . n 
B 2 276 HIS 276 266 266 HIS HIS B . n 
B 2 277 ASP 277 267 267 ASP ASP B . n 
B 2 278 ASN 278 268 268 ASN ASN B . n 
B 2 279 ILE 279 269 269 ILE ILE B . n 
B 2 280 ILE 280 270 270 ILE ILE B . n 
B 2 281 CYS 281 271 271 CYS CYS B . n 
B 2 282 GLY 282 272 272 GLY GLY B . n 
B 2 283 ILE 283 273 273 ILE ILE B . n 
B 2 284 THR 284 274 274 THR THR B . n 
B 2 285 SER 285 275 275 SER SER B . n 
B 2 286 VAL 286 276 276 VAL VAL B . n 
B 2 287 SER 287 277 277 SER SER B . n 
B 2 288 PHE 288 278 278 PHE PHE B . n 
B 2 289 SER 289 279 279 SER SER B . n 
B 2 290 LYS 290 280 280 LYS LYS B . n 
B 2 291 SER 291 281 281 SER SER B . n 
B 2 292 GLY 292 282 282 GLY GLY B . n 
B 2 293 ARG 293 283 283 ARG ARG B . n 
B 2 294 LEU 294 284 284 LEU LEU B . n 
B 2 295 LEU 295 285 285 LEU LEU B . n 
B 2 296 LEU 296 286 286 LEU LEU B . n 
B 2 297 ALA 297 287 287 ALA ALA B . n 
B 2 298 GLY 298 288 288 GLY GLY B . n 
B 2 299 TYR 299 289 289 TYR TYR B . n 
B 2 300 ASP 300 290 290 ASP ASP B . n 
B 2 301 ASP 301 291 291 ASP ASP B . n 
B 2 302 PHE 302 292 292 PHE PHE B . n 
B 2 303 ASN 303 293 293 ASN ASN B . n 
B 2 304 CYS 304 294 294 CYS CYS B . n 
B 2 305 ASN 305 295 295 ASN ASN B . n 
B 2 306 VAL 306 296 296 VAL VAL B . n 
B 2 307 TRP 307 297 297 TRP TRP B . n 
B 2 308 ASP 308 298 298 ASP ASP B . n 
B 2 309 ALA 309 299 299 ALA ALA B . n 
B 2 310 LEU 310 300 300 LEU LEU B . n 
B 2 311 LYS 311 301 301 LYS LYS B . n 
B 2 312 ALA 312 302 302 ALA ALA B . n 
B 2 313 ASP 313 303 303 ASP ASP B . n 
B 2 314 ARG 314 304 304 ARG ARG B . n 
B 2 315 ALA 315 305 305 ALA ALA B . n 
B 2 316 GLY 316 306 306 GLY GLY B . n 
B 2 317 VAL 317 307 307 VAL VAL B . n 
B 2 318 LEU 318 308 308 LEU LEU B . n 
B 2 319 ALA 319 309 309 ALA ALA B . n 
B 2 320 GLY 320 310 310 GLY GLY B . n 
B 2 321 HIS 321 311 311 HIS HIS B . n 
B 2 322 ASP 322 312 312 ASP ASP B . n 
B 2 323 ASN 323 313 313 ASN ASN B . n 
B 2 324 ARG 324 314 314 ARG ARG B . n 
B 2 325 VAL 325 315 315 VAL VAL B . n 
B 2 326 SER 326 316 316 SER SER B . n 
B 2 327 CYS 327 317 317 CYS CYS B . n 
B 2 328 LEU 328 318 318 LEU LEU B . n 
B 2 329 GLY 329 319 319 GLY GLY B . n 
B 2 330 VAL 330 320 320 VAL VAL B . n 
B 2 331 THR 331 321 321 THR THR B . n 
B 2 332 ASP 332 322 322 ASP ASP B . n 
B 2 333 ASP 333 323 323 ASP ASP B . n 
B 2 334 GLY 334 324 324 GLY GLY B . n 
B 2 335 MET 335 325 325 MET MET B . n 
B 2 336 ALA 336 326 326 ALA ALA B . n 
B 2 337 VAL 337 327 327 VAL VAL B . n 
B 2 338 ALA 338 328 328 ALA ALA B . n 
B 2 339 THR 339 329 329 THR THR B . n 
B 2 340 GLY 340 330 330 GLY GLY B . n 
B 2 341 SER 341 331 331 SER SER B . n 
B 2 342 TRP 342 332 332 TRP TRP B . n 
B 2 343 ASP 343 333 333 ASP ASP B . n 
B 2 344 SER 344 334 334 SER SER B . n 
B 2 345 PHE 345 335 335 PHE PHE B . n 
B 2 346 LEU 346 336 336 LEU LEU B . n 
B 2 347 LYS 347 337 337 LYS LYS B . n 
B 2 348 ILE 348 338 338 ILE ILE B . n 
B 2 349 TRP 349 339 339 TRP TRP B . n 
B 2 350 ASN 350 340 340 ASN ASN B . n 
B 2 351 GLY 351 341 341 GLY GLY B . n 
B 2 352 SER 352 342 342 SER SER B . n 
B 2 353 SER 353 343 343 SER SER B . n 
B 2 354 GLY 354 344 ?   ?   ?   B . n 
B 2 355 GLY 355 345 ?   ?   ?   B . n 
B 2 356 GLY 356 346 ?   ?   ?   B . n 
B 2 357 GLY 357 347 ?   ?   ?   B . n 
B 2 358 SER 358 348 ?   ?   ?   B . n 
B 2 359 GLY 359 349 ?   ?   ?   B . n 
B 2 360 GLY 360 350 ?   ?   ?   B . n 
B 2 361 GLY 361 351 ?   ?   ?   B . n 
B 2 362 GLY 362 352 ?   ?   ?   B . n 
B 2 363 SER 363 353 ?   ?   ?   B . n 
B 2 364 SER 364 354 ?   ?   ?   B . n 
B 2 365 GLY 365 355 ?   ?   ?   B . n 
B 2 366 VAL 366 356 ?   ?   ?   B . n 
B 2 367 SER 367 357 ?   ?   ?   B . n 
B 2 368 GLY 368 358 ?   ?   ?   B . n 
B 2 369 TRP 369 359 ?   ?   ?   B . n 
B 2 370 ARG 370 360 ?   ?   ?   B . n 
B 2 371 LEU 371 361 ?   ?   ?   B . n 
B 2 372 PHE 372 362 ?   ?   ?   B . n 
B 2 373 LYS 373 363 ?   ?   ?   B . n 
B 2 374 LYS 374 364 ?   ?   ?   B . n 
B 2 375 ILE 375 365 ?   ?   ?   B . n 
B 2 376 SER 376 366 ?   ?   ?   B . n 
C 3 1   MET 1   1   ?   ?   ?   C . n 
C 3 2   ALA 2   2   ?   ?   ?   C . n 
C 3 3   SER 3   3   ?   ?   ?   C . n 
C 3 4   ASN 4   4   ?   ?   ?   C . n 
C 3 5   ASN 5   5   ?   ?   ?   C . n 
C 3 6   THR 6   6   6   THR THR C . n 
C 3 7   ALA 7   7   7   ALA ALA C . n 
C 3 8   SER 8   8   8   SER SER C . n 
C 3 9   ILE 9   9   9   ILE ILE C . n 
C 3 10  ALA 10  10  10  ALA ALA C . n 
C 3 11  GLN 11  11  11  GLN GLN C . n 
C 3 12  ALA 12  12  12  ALA ALA C . n 
C 3 13  ARG 13  13  13  ARG ARG C . n 
C 3 14  LYS 14  14  14  LYS LYS C . n 
C 3 15  LEU 15  15  15  LEU LEU C . n 
C 3 16  VAL 16  16  16  VAL VAL C . n 
C 3 17  GLU 17  17  17  GLU GLU C . n 
C 3 18  GLN 18  18  18  GLN GLN C . n 
C 3 19  LEU 19  19  19  LEU LEU C . n 
C 3 20  LYS 20  20  20  LYS LYS C . n 
C 3 21  MET 21  21  21  MET MET C . n 
C 3 22  GLU 22  22  22  GLU GLU C . n 
C 3 23  ALA 23  23  23  ALA ALA C . n 
C 3 24  ASN 24  24  24  ASN ASN C . n 
C 3 25  ILE 25  25  25  ILE ILE C . n 
C 3 26  ASP 26  26  26  ASP ASP C . n 
C 3 27  ARG 27  27  27  ARG ARG C . n 
C 3 28  ILE 28  28  28  ILE ILE C . n 
C 3 29  LYS 29  29  29  LYS LYS C . n 
C 3 30  VAL 30  30  30  VAL VAL C . n 
C 3 31  SER 31  31  31  SER SER C . n 
C 3 32  LYS 32  32  32  LYS LYS C . n 
C 3 33  ALA 33  33  33  ALA ALA C . n 
C 3 34  ALA 34  34  34  ALA ALA C . n 
C 3 35  ALA 35  35  35  ALA ALA C . n 
C 3 36  ASP 36  36  36  ASP ASP C . n 
C 3 37  LEU 37  37  37  LEU LEU C . n 
C 3 38  MET 38  38  38  MET MET C . n 
C 3 39  ALA 39  39  39  ALA ALA C . n 
C 3 40  TYR 40  40  40  TYR TYR C . n 
C 3 41  CYS 41  41  41  CYS CYS C . n 
C 3 42  GLU 42  42  42  GLU GLU C . n 
C 3 43  ALA 43  43  43  ALA ALA C . n 
C 3 44  HIS 44  44  44  HIS HIS C . n 
C 3 45  ALA 45  45  45  ALA ALA C . n 
C 3 46  LYS 46  46  46  LYS LYS C . n 
C 3 47  GLU 47  47  47  GLU GLU C . n 
C 3 48  ASP 48  48  48  ASP ASP C . n 
C 3 49  PRO 49  49  49  PRO PRO C . n 
C 3 50  LEU 50  50  50  LEU LEU C . n 
C 3 51  LEU 51  51  51  LEU LEU C . n 
C 3 52  THR 52  52  52  THR THR C . n 
C 3 53  PRO 53  53  53  PRO PRO C . n 
C 3 54  VAL 54  54  54  VAL VAL C . n 
C 3 55  PRO 55  55  55  PRO PRO C . n 
C 3 56  ALA 56  56  56  ALA ALA C . n 
C 3 57  SER 57  57  57  SER SER C . n 
C 3 58  GLU 58  58  58  GLU GLU C . n 
C 3 59  ASN 59  59  59  ASN ASN C . n 
C 3 60  PRO 60  60  60  PRO PRO C . n 
C 3 61  PHE 61  61  61  PHE PHE C . n 
C 3 62  ARG 62  62  62  ARG ARG C . n 
C 3 63  GLU 63  63  ?   ?   ?   C . n 
C 3 64  LYS 64  64  ?   ?   ?   C . n 
C 3 65  LYS 65  65  ?   ?   ?   C . n 
C 3 66  PHE 66  66  ?   ?   ?   C . n 
C 3 67  PHE 67  67  ?   ?   ?   C . n 
C 3 68  CYS 68  68  ?   ?   ?   C . n 
C 3 69  ALA 69  69  ?   ?   ?   C . n 
C 3 70  ILE 70  70  ?   ?   ?   C . n 
C 3 71  LEU 71  71  ?   ?   ?   C . n 
D 4 1   ASP 1   1   1   ASP ASP E . n 
D 4 2   VAL 2   2   2   VAL VAL E . n 
D 4 3   GLN 3   3   3   GLN GLN E . n 
D 4 4   LEU 4   4   4   LEU LEU E . n 
D 4 5   VAL 5   5   5   VAL VAL E . n 
D 4 6   GLU 6   6   6   GLU GLU E . n 
D 4 7   SER 7   7   7   SER SER E . n 
D 4 8   GLY 8   8   8   GLY GLY E . n 
D 4 9   GLY 9   9   9   GLY GLY E . n 
D 4 10  GLY 10  10  10  GLY GLY E . n 
D 4 11  LEU 11  11  11  LEU LEU E . n 
D 4 12  VAL 12  12  12  VAL VAL E . n 
D 4 13  GLN 13  13  13  GLN GLN E . n 
D 4 14  PRO 14  14  14  PRO PRO E . n 
D 4 15  GLY 15  15  15  GLY GLY E . n 
D 4 16  GLY 16  16  16  GLY GLY E . n 
D 4 17  SER 17  17  17  SER SER E . n 
D 4 18  ARG 18  18  18  ARG ARG E . n 
D 4 19  LYS 19  19  19  LYS LYS E . n 
D 4 20  LEU 20  20  20  LEU LEU E . n 
D 4 21  SER 21  21  21  SER SER E . n 
D 4 22  CYS 22  22  22  CYS CYS E . n 
D 4 23  SER 23  23  23  SER SER E . n 
D 4 24  ALA 24  24  24  ALA ALA E . n 
D 4 25  SER 25  25  25  SER SER E . n 
D 4 26  GLY 26  26  26  GLY GLY E . n 
D 4 27  PHE 27  27  27  PHE PHE E . n 
D 4 28  ALA 28  28  28  ALA ALA E . n 
D 4 29  PHE 29  29  29  PHE PHE E . n 
D 4 30  SER 30  30  30  SER SER E . n 
D 4 31  SER 31  31  31  SER SER E . n 
D 4 32  PHE 32  32  32  PHE PHE E . n 
D 4 33  GLY 33  33  33  GLY GLY E . n 
D 4 34  MET 34  34  34  MET MET E . n 
D 4 35  HIS 35  35  35  HIS HIS E . n 
D 4 36  TRP 36  36  36  TRP TRP E . n 
D 4 37  VAL 37  37  37  VAL VAL E . n 
D 4 38  ARG 38  38  38  ARG ARG E . n 
D 4 39  GLN 39  39  39  GLN GLN E . n 
D 4 40  ALA 40  40  40  ALA ALA E . n 
D 4 41  PRO 41  41  41  PRO PRO E . n 
D 4 42  GLU 42  42  42  GLU GLU E . n 
D 4 43  LYS 43  43  43  LYS LYS E . n 
D 4 44  GLY 44  44  44  GLY GLY E . n 
D 4 45  LEU 45  45  45  LEU LEU E . n 
D 4 46  GLU 46  46  46  GLU GLU E . n 
D 4 47  TRP 47  47  47  TRP TRP E . n 
D 4 48  VAL 48  48  48  VAL VAL E . n 
D 4 49  ALA 49  49  49  ALA ALA E . n 
D 4 50  TYR 50  50  50  TYR TYR E . n 
D 4 51  ILE 51  51  51  ILE ILE E . n 
D 4 52  SER 52  52  52  SER SER E . n 
D 4 53  SER 53  53  53  SER SER E . n 
D 4 54  GLY 54  54  54  GLY GLY E . n 
D 4 55  SER 55  55  55  SER SER E . n 
D 4 56  GLY 56  56  56  GLY GLY E . n 
D 4 57  THR 57  57  57  THR THR E . n 
D 4 58  ILE 58  58  58  ILE ILE E . n 
D 4 59  TYR 59  59  59  TYR TYR E . n 
D 4 60  TYR 60  60  60  TYR TYR E . n 
D 4 61  ALA 61  61  61  ALA ALA E . n 
D 4 62  ASP 62  62  62  ASP ASP E . n 
D 4 63  THR 63  63  63  THR THR E . n 
D 4 64  VAL 64  64  64  VAL VAL E . n 
D 4 65  LYS 65  65  65  LYS LYS E . n 
D 4 66  GLY 66  66  66  GLY GLY E . n 
D 4 67  ARG 67  67  67  ARG ARG E . n 
D 4 68  PHE 68  68  68  PHE PHE E . n 
D 4 69  THR 69  69  69  THR THR E . n 
D 4 70  ILE 70  70  70  ILE ILE E . n 
D 4 71  SER 71  71  71  SER SER E . n 
D 4 72  ARG 72  72  72  ARG ARG E . n 
D 4 73  ASP 73  73  73  ASP ASP E . n 
D 4 74  ASP 74  74  74  ASP ASP E . n 
D 4 75  PRO 75  75  75  PRO PRO E . n 
D 4 76  LYS 76  76  76  LYS LYS E . n 
D 4 77  ASN 77  77  77  ASN ASN E . n 
D 4 78  THR 78  78  78  THR THR E . n 
D 4 79  LEU 79  79  79  LEU LEU E . n 
D 4 80  PHE 80  80  80  PHE PHE E . n 
D 4 81  LEU 81  81  81  LEU LEU E . n 
D 4 82  GLN 82  82  82  GLN GLN E . n 
D 4 83  MET 83  83  83  MET MET E . n 
D 4 84  THR 84  84  84  THR THR E . n 
D 4 85  SER 85  85  85  SER SER E . n 
D 4 86  LEU 86  86  86  LEU LEU E . n 
D 4 87  ARG 87  87  87  ARG ARG E . n 
D 4 88  SER 88  88  88  SER SER E . n 
D 4 89  GLU 89  89  89  GLU GLU E . n 
D 4 90  ASP 90  90  90  ASP ASP E . n 
D 4 91  THR 91  91  91  THR THR E . n 
D 4 92  ALA 92  92  92  ALA ALA E . n 
D 4 93  MET 93  93  93  MET MET E . n 
D 4 94  TYR 94  94  94  TYR TYR E . n 
D 4 95  TYR 95  95  95  TYR TYR E . n 
D 4 96  CYS 96  96  96  CYS CYS E . n 
D 4 97  VAL 97  97  97  VAL VAL E . n 
D 4 98  ARG 98  98  98  ARG ARG E . n 
D 4 99  SER 99  99  99  SER SER E . n 
D 4 100 ILE 100 100 100 ILE ILE E . n 
D 4 101 TYR 101 101 101 TYR TYR E . n 
D 4 102 TYR 102 102 102 TYR TYR E . n 
D 4 103 TYR 103 103 103 TYR TYR E . n 
D 4 104 GLY 104 104 104 GLY GLY E . n 
D 4 105 SER 105 105 105 SER SER E . n 
D 4 106 SER 106 106 106 SER SER E . n 
D 4 107 PRO 107 107 107 PRO PRO E . n 
D 4 108 PHE 108 108 108 PHE PHE E . n 
D 4 109 ASP 109 109 109 ASP ASP E . n 
D 4 110 PHE 110 110 110 PHE PHE E . n 
D 4 111 TRP 111 111 111 TRP TRP E . n 
D 4 112 GLY 112 112 112 GLY GLY E . n 
D 4 113 GLN 113 113 113 GLN GLN E . n 
D 4 114 GLY 114 114 114 GLY GLY E . n 
D 4 115 THR 115 115 115 THR THR E . n 
D 4 116 THR 116 116 116 THR THR E . n 
D 4 117 LEU 117 117 117 LEU LEU E . n 
D 4 118 THR 118 118 118 THR THR E . n 
D 4 119 VAL 119 119 119 VAL VAL E . n 
D 4 120 SER 120 120 120 SER SER E . n 
D 4 121 SER 121 121 ?   ?   ?   E . n 
D 4 122 GLY 122 122 ?   ?   ?   E . n 
D 4 123 GLY 123 123 ?   ?   ?   E . n 
D 4 124 GLY 124 124 ?   ?   ?   E . n 
D 4 125 GLY 125 125 ?   ?   ?   E . n 
D 4 126 SER 126 126 ?   ?   ?   E . n 
D 4 127 GLY 127 127 ?   ?   ?   E . n 
D 4 128 GLY 128 128 ?   ?   ?   E . n 
D 4 129 GLY 129 129 ?   ?   ?   E . n 
D 4 130 GLY 130 130 ?   ?   ?   E . n 
D 4 131 SER 131 131 ?   ?   ?   E . n 
D 4 132 GLY 132 132 ?   ?   ?   E . n 
D 4 133 GLY 133 133 ?   ?   ?   E . n 
D 4 134 GLY 134 134 ?   ?   ?   E . n 
D 4 135 GLY 135 135 ?   ?   ?   E . n 
D 4 136 SER 136 136 ?   ?   ?   E . n 
D 4 137 ASP 137 137 137 ASP ASP E . n 
D 4 138 ILE 138 138 138 ILE ILE E . n 
D 4 139 VAL 139 139 139 VAL VAL E . n 
D 4 140 MET 140 140 140 MET MET E . n 
D 4 141 THR 141 141 141 THR THR E . n 
D 4 142 GLN 142 142 142 GLN GLN E . n 
D 4 143 ALA 143 143 143 ALA ALA E . n 
D 4 144 THR 144 144 144 THR THR E . n 
D 4 145 SER 145 145 145 SER SER E . n 
D 4 146 SER 146 146 146 SER SER E . n 
D 4 147 VAL 147 147 147 VAL VAL E . n 
D 4 148 PRO 148 148 148 PRO PRO E . n 
D 4 149 VAL 149 149 149 VAL VAL E . n 
D 4 150 THR 150 150 150 THR THR E . n 
D 4 151 PRO 151 151 151 PRO PRO E . n 
D 4 152 GLY 152 152 152 GLY GLY E . n 
D 4 153 GLU 153 153 153 GLU GLU E . n 
D 4 154 SER 154 154 154 SER SER E . n 
D 4 155 VAL 155 155 155 VAL VAL E . n 
D 4 156 SER 156 156 156 SER SER E . n 
D 4 157 ILE 157 157 157 ILE ILE E . n 
D 4 158 SER 158 158 158 SER SER E . n 
D 4 159 CYS 159 159 159 CYS CYS E . n 
D 4 160 ARG 160 160 160 ARG ARG E . n 
D 4 161 SER 161 161 161 SER SER E . n 
D 4 162 SER 162 162 162 SER SER E . n 
D 4 163 LYS 163 163 163 LYS LYS E . n 
D 4 164 SER 164 164 164 SER SER E . n 
D 4 165 LEU 165 165 165 LEU LEU E . n 
D 4 166 LEU 166 166 166 LEU LEU E . n 
D 4 167 HIS 167 167 167 HIS HIS E . n 
D 4 168 SER 168 168 168 SER SER E . n 
D 4 169 ASN 169 169 169 ASN ASN E . n 
D 4 170 GLY 170 170 170 GLY GLY E . n 
D 4 171 ASN 171 171 171 ASN ASN E . n 
D 4 172 THR 172 172 172 THR THR E . n 
D 4 173 TYR 173 173 173 TYR TYR E . n 
D 4 174 LEU 174 174 174 LEU LEU E . n 
D 4 175 TYR 175 175 175 TYR TYR E . n 
D 4 176 TRP 176 176 176 TRP TRP E . n 
D 4 177 PHE 177 177 177 PHE PHE E . n 
D 4 178 LEU 178 178 178 LEU LEU E . n 
D 4 179 GLN 179 179 179 GLN GLN E . n 
D 4 180 ARG 180 180 180 ARG ARG E . n 
D 4 181 PRO 181 181 181 PRO PRO E . n 
D 4 182 GLY 182 182 182 GLY GLY E . n 
D 4 183 GLN 183 183 183 GLN GLN E . n 
D 4 184 SER 184 184 184 SER SER E . n 
D 4 185 PRO 185 185 185 PRO PRO E . n 
D 4 186 GLN 186 186 186 GLN GLN E . n 
D 4 187 LEU 187 187 187 LEU LEU E . n 
D 4 188 LEU 188 188 188 LEU LEU E . n 
D 4 189 ILE 189 189 189 ILE ILE E . n 
D 4 190 TYR 190 190 190 TYR TYR E . n 
D 4 191 ARG 191 191 191 ARG ARG E . n 
D 4 192 MET 192 192 192 MET MET E . n 
D 4 193 SER 193 193 193 SER SER E . n 
D 4 194 ASN 194 194 194 ASN ASN E . n 
D 4 195 LEU 195 195 195 LEU LEU E . n 
D 4 196 ALA 196 196 196 ALA ALA E . n 
D 4 197 SER 197 197 197 SER SER E . n 
D 4 198 GLY 198 198 198 GLY GLY E . n 
D 4 199 VAL 199 199 199 VAL VAL E . n 
D 4 200 PRO 200 200 200 PRO PRO E . n 
D 4 201 ASP 201 201 201 ASP ASP E . n 
D 4 202 ARG 202 202 202 ARG ARG E . n 
D 4 203 PHE 203 203 203 PHE PHE E . n 
D 4 204 SER 204 204 204 SER SER E . n 
D 4 205 GLY 205 205 205 GLY GLY E . n 
D 4 206 SER 206 206 206 SER SER E . n 
D 4 207 GLY 207 207 207 GLY GLY E . n 
D 4 208 SER 208 208 208 SER SER E . n 
D 4 209 GLY 209 209 209 GLY GLY E . n 
D 4 210 THR 210 210 210 THR THR E . n 
D 4 211 ALA 211 211 211 ALA ALA E . n 
D 4 212 PHE 212 212 212 PHE PHE E . n 
D 4 213 THR 213 213 213 THR THR E . n 
D 4 214 LEU 214 214 214 LEU LEU E . n 
D 4 215 THR 215 215 215 THR THR E . n 
D 4 216 ILE 216 216 216 ILE ILE E . n 
D 4 217 SER 217 217 217 SER SER E . n 
D 4 218 ARG 218 218 218 ARG ARG E . n 
D 4 219 LEU 219 219 219 LEU LEU E . n 
D 4 220 GLU 220 220 220 GLU GLU E . n 
D 4 221 ALA 221 221 221 ALA ALA E . n 
D 4 222 GLU 222 222 222 GLU GLU E . n 
D 4 223 ASP 223 223 223 ASP ASP E . n 
D 4 224 VAL 224 224 224 VAL VAL E . n 
D 4 225 GLY 225 225 225 GLY GLY E . n 
D 4 226 VAL 226 226 226 VAL VAL E . n 
D 4 227 TYR 227 227 227 TYR TYR E . n 
D 4 228 TYR 228 228 228 TYR TYR E . n 
D 4 229 CYS 229 229 229 CYS CYS E . n 
D 4 230 MET 230 230 230 MET MET E . n 
D 4 231 GLN 231 231 231 GLN GLN E . n 
D 4 232 HIS 232 232 232 HIS HIS E . n 
D 4 233 LEU 233 233 233 LEU LEU E . n 
D 4 234 GLU 234 234 234 GLU GLU E . n 
D 4 235 TYR 235 235 235 TYR TYR E . n 
D 4 236 PRO 236 236 236 PRO PRO E . n 
D 4 237 LEU 237 237 237 LEU LEU E . n 
D 4 238 THR 238 238 238 THR THR E . n 
D 4 239 PHE 239 239 239 PHE PHE E . n 
D 4 240 GLY 240 240 240 GLY GLY E . n 
D 4 241 ALA 241 241 241 ALA ALA E . n 
D 4 242 GLY 242 242 242 GLY GLY E . n 
D 4 243 THR 243 243 243 THR THR E . n 
D 4 244 LYS 244 244 244 LYS LYS E . n 
D 4 245 LEU 245 245 245 LEU LEU E . n 
D 4 246 GLU 246 246 246 GLU GLU E . n 
D 4 247 LEU 247 247 247 LEU LEU E . n 
D 4 248 LEU 248 248 ?   ?   ?   E . n 
D 4 249 GLU 249 249 ?   ?   ?   E . n 
D 4 250 GLU 250 250 ?   ?   ?   E . n 
D 4 251 ASN 251 251 ?   ?   ?   E . n 
D 4 252 LEU 252 252 ?   ?   ?   E . n 
D 4 253 TYR 253 253 ?   ?   ?   E . n 
D 4 254 PHE 254 254 ?   ?   ?   E . n 
D 4 255 GLN 255 255 ?   ?   ?   E . n 
E 5 1   ASP 1   -52 ?   ?   ?   R . n 
E 5 2   TYR 2   -51 ?   ?   ?   R . n 
E 5 3   LYS 3   -50 ?   ?   ?   R . n 
E 5 4   ASP 4   -49 ?   ?   ?   R . n 
E 5 5   ASP 5   -48 ?   ?   ?   R . n 
E 5 6   ASP 6   -47 ?   ?   ?   R . n 
E 5 7   ASP 7   -46 ?   ?   ?   R . n 
E 5 8   HIS 8   -45 ?   ?   ?   R . n 
E 5 9   HIS 9   -44 ?   ?   ?   R . n 
E 5 10  HIS 10  -43 ?   ?   ?   R . n 
E 5 11  HIS 11  -42 ?   ?   ?   R . n 
E 5 12  HIS 12  -41 ?   ?   ?   R . n 
E 5 13  HIS 13  -40 ?   ?   ?   R . n 
E 5 14  HIS 14  -39 ?   ?   ?   R . n 
E 5 15  HIS 15  -38 ?   ?   ?   R . n 
E 5 16  GLY 16  -37 ?   ?   ?   R . n 
E 5 17  GLN 17  -36 ?   ?   ?   R . n 
E 5 18  PRO 18  -35 ?   ?   ?   R . n 
E 5 19  GLY 19  -34 ?   ?   ?   R . n 
E 5 20  ASN 20  -33 ?   ?   ?   R . n 
E 5 21  GLY 21  -32 ?   ?   ?   R . n 
E 5 22  SER 22  -31 ?   ?   ?   R . n 
E 5 23  ALA 23  -30 ?   ?   ?   R . n 
E 5 24  PHE 24  -29 ?   ?   ?   R . n 
E 5 25  LEU 25  -28 ?   ?   ?   R . n 
E 5 26  LEU 26  -27 ?   ?   ?   R . n 
E 5 27  ALA 27  -26 ?   ?   ?   R . n 
E 5 28  PRO 28  -25 ?   ?   ?   R . n 
E 5 29  ASN 29  -24 ?   ?   ?   R . n 
E 5 30  GLY 30  -23 ?   ?   ?   R . n 
E 5 31  SER 31  -22 ?   ?   ?   R . n 
E 5 32  HIS 32  -21 ?   ?   ?   R . n 
E 5 33  ALA 33  -20 ?   ?   ?   R . n 
E 5 34  PRO 34  -19 ?   ?   ?   R . n 
E 5 35  ASP 35  -18 ?   ?   ?   R . n 
E 5 36  HIS 36  -17 ?   ?   ?   R . n 
E 5 37  ASN 37  -16 ?   ?   ?   R . n 
E 5 38  VAL 38  -15 ?   ?   ?   R . n 
E 5 39  THR 39  -14 ?   ?   ?   R . n 
E 5 40  GLN 40  -13 ?   ?   ?   R . n 
E 5 41  GLN 41  -12 ?   ?   ?   R . n 
E 5 42  ARG 42  -11 ?   ?   ?   R . n 
E 5 43  ASP 43  -10 ?   ?   ?   R . n 
E 5 44  GLU 44  -9  ?   ?   ?   R . n 
E 5 45  GLU 45  -8  ?   ?   ?   R . n 
E 5 46  ASN 46  -7  ?   ?   ?   R . n 
E 5 47  LEU 47  -6  ?   ?   ?   R . n 
E 5 48  TYR 48  -5  ?   ?   ?   R . n 
E 5 49  PHE 49  -4  ?   ?   ?   R . n 
E 5 50  GLN 50  -3  ?   ?   ?   R . n 
E 5 51  GLY 51  -2  ?   ?   ?   R . n 
E 5 52  VAL 52  -1  ?   ?   ?   R . n 
E 5 53  ASP 53  0   ?   ?   ?   R . n 
E 5 54  MET 54  1   ?   ?   ?   R . n 
E 5 55  SER 55  2   ?   ?   ?   R . n 
E 5 56  VAL 56  3   ?   ?   ?   R . n 
E 5 57  GLY 57  4   ?   ?   ?   R . n 
E 5 58  ALA 58  5   ?   ?   ?   R . n 
E 5 59  MET 59  6   ?   ?   ?   R . n 
E 5 60  LYS 60  7   ?   ?   ?   R . n 
E 5 61  LYS 61  8   ?   ?   ?   R . n 
E 5 62  GLY 62  9   ?   ?   ?   R . n 
E 5 63  VAL 63  10  ?   ?   ?   R . n 
E 5 64  GLY 64  11  ?   ?   ?   R . n 
E 5 65  ARG 65  12  ?   ?   ?   R . n 
E 5 66  ALA 66  13  ?   ?   ?   R . n 
E 5 67  VAL 67  14  ?   ?   ?   R . n 
E 5 68  GLY 68  15  ?   ?   ?   R . n 
E 5 69  LEU 69  16  ?   ?   ?   R . n 
E 5 70  GLY 70  17  ?   ?   ?   R . n 
E 5 71  GLY 71  18  ?   ?   ?   R . n 
E 5 72  GLY 72  19  ?   ?   ?   R . n 
E 5 73  SER 73  20  ?   ?   ?   R . n 
E 5 74  GLY 74  21  ?   ?   ?   R . n 
E 5 75  CYS 75  22  ?   ?   ?   R . n 
E 5 76  GLN 76  23  ?   ?   ?   R . n 
E 5 77  ALA 77  24  ?   ?   ?   R . n 
E 5 78  THR 78  25  ?   ?   ?   R . n 
E 5 79  GLU 79  26  ?   ?   ?   R . n 
E 5 80  GLU 80  27  ?   ?   ?   R . n 
E 5 81  ASP 81  28  ?   ?   ?   R . n 
E 5 82  PRO 82  29  ?   ?   ?   R . n 
E 5 83  LEU 83  30  ?   ?   ?   R . n 
E 5 84  PRO 84  31  ?   ?   ?   R . n 
E 5 85  ASN 85  32  ?   ?   ?   R . n 
E 5 86  CYS 86  33  ?   ?   ?   R . n 
E 5 87  GLY 87  34  ?   ?   ?   R . n 
E 5 88  ALA 88  35  ?   ?   ?   R . n 
E 5 89  CYS 89  36  ?   ?   ?   R . n 
E 5 90  ALA 90  37  ?   ?   ?   R . n 
E 5 91  PRO 91  38  ?   ?   ?   R . n 
E 5 92  GLY 92  39  ?   ?   ?   R . n 
E 5 93  GLN 93  40  ?   ?   ?   R . n 
E 5 94  GLY 94  41  ?   ?   ?   R . n 
E 5 95  GLY 95  42  ?   ?   ?   R . n 
E 5 96  ARG 96  43  ?   ?   ?   R . n 
E 5 97  ARG 97  44  ?   ?   ?   R . n 
E 5 98  TRP 98  45  ?   ?   ?   R . n 
E 5 99  ARG 99  46  ?   ?   ?   R . n 
E 5 100 LEU 100 47  ?   ?   ?   R . n 
E 5 101 PRO 101 48  ?   ?   ?   R . n 
E 5 102 GLN 102 49  ?   ?   ?   R . n 
E 5 103 PRO 103 50  ?   ?   ?   R . n 
E 5 104 ALA 104 51  ?   ?   ?   R . n 
E 5 105 TRP 105 52  ?   ?   ?   R . n 
E 5 106 VAL 106 53  ?   ?   ?   R . n 
E 5 107 GLU 107 54  ?   ?   ?   R . n 
E 5 108 GLY 108 55  ?   ?   ?   R . n 
E 5 109 SER 109 56  ?   ?   ?   R . n 
E 5 110 SER 110 57  ?   ?   ?   R . n 
E 5 111 ALA 111 58  ?   ?   ?   R . n 
E 5 112 ARG 112 59  ?   ?   ?   R . n 
E 5 113 LEU 113 60  ?   ?   ?   R . n 
E 5 114 TRP 114 61  ?   ?   ?   R . n 
E 5 115 GLU 115 62  ?   ?   ?   R . n 
E 5 116 GLN 116 63  ?   ?   ?   R . n 
E 5 117 ALA 117 64  ?   ?   ?   R . n 
E 5 118 THR 118 65  ?   ?   ?   R . n 
E 5 119 GLY 119 66  ?   ?   ?   R . n 
E 5 120 THR 120 67  ?   ?   ?   R . n 
E 5 121 GLY 121 68  ?   ?   ?   R . n 
E 5 122 TRP 122 69  ?   ?   ?   R . n 
E 5 123 MET 123 70  ?   ?   ?   R . n 
E 5 124 ASP 124 71  ?   ?   ?   R . n 
E 5 125 LEU 125 72  ?   ?   ?   R . n 
E 5 126 GLU 126 73  ?   ?   ?   R . n 
E 5 127 ALA 127 74  ?   ?   ?   R . n 
E 5 128 SER 128 75  ?   ?   ?   R . n 
E 5 129 LEU 129 76  ?   ?   ?   R . n 
E 5 130 LEU 130 77  ?   ?   ?   R . n 
E 5 131 PRO 131 78  ?   ?   ?   R . n 
E 5 132 THR 132 79  ?   ?   ?   R . n 
E 5 133 GLY 133 80  ?   ?   ?   R . n 
E 5 134 PRO 134 81  ?   ?   ?   R . n 
E 5 135 ASN 135 82  ?   ?   ?   R . n 
E 5 136 ALA 136 83  ?   ?   ?   R . n 
E 5 137 SER 137 84  ?   ?   ?   R . n 
E 5 138 ASN 138 85  ?   ?   ?   R . n 
E 5 139 THR 139 86  ?   ?   ?   R . n 
E 5 140 SER 140 87  ?   ?   ?   R . n 
E 5 141 ASP 141 88  ?   ?   ?   R . n 
E 5 142 GLY 142 89  ?   ?   ?   R . n 
E 5 143 PRO 143 90  ?   ?   ?   R . n 
E 5 144 ASP 144 91  ?   ?   ?   R . n 
E 5 145 ASN 145 92  ?   ?   ?   R . n 
E 5 146 LEU 146 93  ?   ?   ?   R . n 
E 5 147 THR 147 94  ?   ?   ?   R . n 
E 5 148 SER 148 95  ?   ?   ?   R . n 
E 5 149 ALA 149 96  ?   ?   ?   R . n 
E 5 150 GLY 150 97  ?   ?   ?   R . n 
E 5 151 SER 151 98  ?   ?   ?   R . n 
E 5 152 PRO 152 99  ?   ?   ?   R . n 
E 5 153 PRO 153 100 ?   ?   ?   R . n 
E 5 154 ARG 154 101 ?   ?   ?   R . n 
E 5 155 THR 155 102 ?   ?   ?   R . n 
E 5 156 GLY 156 103 ?   ?   ?   R . n 
E 5 157 SER 157 104 ?   ?   ?   R . n 
E 5 158 ILE 158 105 ?   ?   ?   R . n 
E 5 159 SER 159 106 ?   ?   ?   R . n 
E 5 160 TYR 160 107 107 TYR TYR R . n 
E 5 161 ILE 161 108 108 ILE ILE R . n 
E 5 162 ASN 162 109 109 ASN ASN R . n 
E 5 163 ILE 163 110 110 ILE ILE R . n 
E 5 164 ILE 164 111 111 ILE ILE R . n 
E 5 165 MET 165 112 112 MET MET R . n 
E 5 166 PRO 166 113 113 PRO PRO R . n 
E 5 167 SER 167 114 114 SER SER R . n 
E 5 168 VAL 168 115 115 VAL VAL R . n 
E 5 169 PHE 169 116 116 PHE PHE R . n 
E 5 170 GLY 170 117 117 GLY GLY R . n 
E 5 171 THR 171 118 118 THR THR R . n 
E 5 172 ILE 172 119 119 ILE ILE R . n 
E 5 173 CYS 173 120 120 CYS CYS R . n 
E 5 174 LEU 174 121 121 LEU LEU R . n 
E 5 175 LEU 175 122 122 LEU LEU R . n 
E 5 176 GLY 176 123 123 GLY GLY R . n 
E 5 177 ILE 177 124 124 ILE ILE R . n 
E 5 178 ILE 178 125 125 ILE ILE R . n 
E 5 179 GLY 179 126 126 GLY GLY R . n 
E 5 180 ASN 180 127 127 ASN ASN R . n 
E 5 181 SER 181 128 128 SER SER R . n 
E 5 182 THR 182 129 129 THR THR R . n 
E 5 183 VAL 183 130 130 VAL VAL R . n 
E 5 184 ILE 184 131 131 ILE ILE R . n 
E 5 185 PHE 185 132 132 PHE PHE R . n 
E 5 186 ALA 186 133 133 ALA ALA R . n 
E 5 187 VAL 187 134 134 VAL VAL R . n 
E 5 188 VAL 188 135 135 VAL VAL R . n 
E 5 189 LYS 189 136 136 LYS LYS R . n 
E 5 190 LYS 190 137 137 LYS LYS R . n 
E 5 191 SER 191 138 138 SER SER R . n 
E 5 192 LYS 192 139 139 LYS LYS R . n 
E 5 193 LEU 193 140 140 LEU LEU R . n 
E 5 194 HIS 194 141 141 HIS HIS R . n 
E 5 195 TRP 195 142 142 TRP TRP R . n 
E 5 196 CYS 196 143 143 CYS CYS R . n 
E 5 197 ASN 197 144 144 ASN ASN R . n 
E 5 198 ASN 198 145 145 ASN ASN R . n 
E 5 199 VAL 199 146 146 VAL VAL R . n 
E 5 200 PRO 200 147 147 PRO PRO R . n 
E 5 201 ASP 201 148 148 ASP ASP R . n 
E 5 202 ILE 202 149 149 ILE ILE R . n 
E 5 203 PHE 203 150 150 PHE PHE R . n 
E 5 204 ILE 204 151 151 ILE ILE R . n 
E 5 205 ILE 205 152 152 ILE ILE R . n 
E 5 206 ASN 206 153 153 ASN ASN R . n 
E 5 207 LEU 207 154 154 LEU LEU R . n 
E 5 208 SER 208 155 155 SER SER R . n 
E 5 209 VAL 209 156 156 VAL VAL R . n 
E 5 210 VAL 210 157 157 VAL VAL R . n 
E 5 211 ASP 211 158 158 ASP ASP R . n 
E 5 212 LEU 212 159 159 LEU LEU R . n 
E 5 213 LEU 213 160 160 LEU LEU R . n 
E 5 214 PHE 214 161 161 PHE PHE R . n 
E 5 215 LEU 215 162 162 LEU LEU R . n 
E 5 216 LEU 216 163 163 LEU LEU R . n 
E 5 217 GLY 217 164 164 GLY GLY R . n 
E 5 218 MET 218 165 165 MET MET R . n 
E 5 219 PRO 219 166 166 PRO PRO R . n 
E 5 220 PHE 220 167 167 PHE PHE R . n 
E 5 221 MET 221 168 168 MET MET R . n 
E 5 222 ILE 222 169 169 ILE ILE R . n 
E 5 223 HIS 223 170 170 HIS HIS R . n 
E 5 224 GLN 224 171 171 GLN GLN R . n 
E 5 225 LEU 225 172 172 LEU LEU R . n 
E 5 226 MET 226 173 173 MET MET R . n 
E 5 227 GLY 227 174 174 GLY GLY R . n 
E 5 228 ASN 228 175 175 ASN ASN R . n 
E 5 229 GLY 229 176 176 GLY GLY R . n 
E 5 230 VAL 230 177 177 VAL VAL R . n 
E 5 231 TRP 231 178 178 TRP TRP R . n 
E 5 232 HIS 232 179 179 HIS HIS R . n 
E 5 233 PHE 233 180 180 PHE PHE R . n 
E 5 234 GLY 234 181 181 GLY GLY R . n 
E 5 235 GLU 235 182 182 GLU GLU R . n 
E 5 236 THR 236 183 183 THR THR R . n 
E 5 237 MET 237 184 184 MET MET R . n 
E 5 238 CYS 238 185 185 CYS CYS R . n 
E 5 239 THR 239 186 186 THR THR R . n 
E 5 240 LEU 240 187 187 LEU LEU R . n 
E 5 241 ILE 241 188 188 ILE ILE R . n 
E 5 242 THR 242 189 189 THR THR R . n 
E 5 243 ALA 243 190 190 ALA ALA R . n 
E 5 244 MET 244 191 191 MET MET R . n 
E 5 245 ASP 245 192 192 ASP ASP R . n 
E 5 246 ALA 246 193 193 ALA ALA R . n 
E 5 247 ASN 247 194 194 ASN ASN R . n 
E 5 248 SER 248 195 195 SER SER R . n 
E 5 249 GLN 249 196 196 GLN GLN R . n 
E 5 250 PHE 250 197 197 PHE PHE R . n 
E 5 251 THR 251 198 198 THR THR R . n 
E 5 252 SER 252 199 199 SER SER R . n 
E 5 253 THR 253 200 200 THR THR R . n 
E 5 254 TYR 254 201 201 TYR TYR R . n 
E 5 255 ILE 255 202 202 ILE ILE R . n 
E 5 256 LEU 256 203 203 LEU LEU R . n 
E 5 257 THR 257 204 204 THR THR R . n 
E 5 258 ALA 258 205 205 ALA ALA R . n 
E 5 259 MET 259 206 206 MET MET R . n 
E 5 260 ALA 260 207 207 ALA ALA R . n 
E 5 261 ILE 261 208 208 ILE ILE R . n 
E 5 262 ASP 262 209 209 ASP ASP R . n 
E 5 263 ARG 263 210 210 ARG ARG R . n 
E 5 264 TYR 264 211 211 TYR TYR R . n 
E 5 265 LEU 265 212 212 LEU LEU R . n 
E 5 266 ALA 266 213 213 ALA ALA R . n 
E 5 267 THR 267 214 214 THR THR R . n 
E 5 268 VAL 268 215 215 VAL VAL R . n 
E 5 269 HIS 269 216 216 HIS HIS R . n 
E 5 270 PRO 270 217 217 PRO PRO R . n 
E 5 271 ILE 271 218 218 ILE ILE R . n 
E 5 272 SER 272 219 219 SER SER R . n 
E 5 273 SER 273 220 220 SER SER R . n 
E 5 274 THR 274 221 221 THR THR R . n 
E 5 275 LYS 275 222 222 LYS LYS R . n 
E 5 276 PHE 276 223 223 PHE PHE R . n 
E 5 277 ARG 277 224 224 ARG ARG R . n 
E 5 278 LYS 278 225 225 LYS LYS R . n 
E 5 279 PRO 279 226 226 PRO PRO R . n 
E 5 280 SER 280 227 227 SER SER R . n 
E 5 281 VAL 281 228 228 VAL VAL R . n 
E 5 282 ALA 282 229 229 ALA ALA R . n 
E 5 283 THR 283 230 230 THR THR R . n 
E 5 284 LEU 284 231 231 LEU LEU R . n 
E 5 285 VAL 285 232 232 VAL VAL R . n 
E 5 286 ILE 286 233 233 ILE ILE R . n 
E 5 287 CYS 287 234 234 CYS CYS R . n 
E 5 288 LEU 288 235 235 LEU LEU R . n 
E 5 289 LEU 289 236 236 LEU LEU R . n 
E 5 290 TRP 290 237 237 TRP TRP R . n 
E 5 291 ALA 291 238 238 ALA ALA R . n 
E 5 292 LEU 292 239 239 LEU LEU R . n 
E 5 293 SER 293 240 240 SER SER R . n 
E 5 294 PHE 294 241 241 PHE PHE R . n 
E 5 295 ILE 295 242 242 ILE ILE R . n 
E 5 296 SER 296 243 243 SER SER R . n 
E 5 297 ILE 297 244 244 ILE ILE R . n 
E 5 298 THR 298 245 245 THR THR R . n 
E 5 299 PRO 299 246 246 PRO PRO R . n 
E 5 300 VAL 300 247 247 VAL VAL R . n 
E 5 301 TRP 301 248 248 TRP TRP R . n 
E 5 302 LEU 302 249 249 LEU LEU R . n 
E 5 303 TYR 303 250 250 TYR TYR R . n 
E 5 304 ALA 304 251 251 ALA ALA R . n 
E 5 305 ARG 305 252 252 ARG ARG R . n 
E 5 306 LEU 306 253 253 LEU LEU R . n 
E 5 307 ILE 307 254 254 ILE ILE R . n 
E 5 308 PRO 308 255 255 PRO PRO R . n 
E 5 309 PHE 309 256 256 PHE PHE R . n 
E 5 310 PRO 310 257 257 PRO PRO R . n 
E 5 311 GLY 311 258 258 GLY GLY R . n 
E 5 312 GLY 312 259 259 GLY GLY R . n 
E 5 313 ALA 313 260 260 ALA ALA R . n 
E 5 314 VAL 314 261 261 VAL VAL R . n 
E 5 315 GLY 315 262 262 GLY GLY R . n 
E 5 316 CYS 316 263 263 CYS CYS R . n 
E 5 317 GLY 317 264 264 GLY GLY R . n 
E 5 318 ILE 318 265 265 ILE ILE R . n 
E 5 319 ARG 319 266 266 ARG ARG R . n 
E 5 320 LEU 320 267 267 LEU LEU R . n 
E 5 321 PRO 321 268 268 PRO PRO R . n 
E 5 322 ASN 322 269 269 ASN ASN R . n 
E 5 323 PRO 323 270 270 PRO PRO R . n 
E 5 324 ASP 324 271 271 ASP ASP R . n 
E 5 325 THR 325 272 272 THR THR R . n 
E 5 326 ASP 326 273 273 ASP ASP R . n 
E 5 327 LEU 327 274 274 LEU LEU R . n 
E 5 328 TYR 328 275 275 TYR TYR R . n 
E 5 329 TRP 329 276 276 TRP TRP R . n 
E 5 330 PHE 330 277 277 PHE PHE R . n 
E 5 331 THR 331 278 278 THR THR R . n 
E 5 332 LEU 332 279 279 LEU LEU R . n 
E 5 333 TYR 333 280 280 TYR TYR R . n 
E 5 334 GLN 334 281 281 GLN GLN R . n 
E 5 335 PHE 335 282 282 PHE PHE R . n 
E 5 336 PHE 336 283 283 PHE PHE R . n 
E 5 337 LEU 337 284 284 LEU LEU R . n 
E 5 338 ALA 338 285 285 ALA ALA R . n 
E 5 339 PHE 339 286 286 PHE PHE R . n 
E 5 340 ALA 340 287 287 ALA ALA R . n 
E 5 341 LEU 341 288 288 LEU LEU R . n 
E 5 342 PRO 342 289 289 PRO PRO R . n 
E 5 343 PHE 343 290 290 PHE PHE R . n 
E 5 344 VAL 344 291 291 VAL VAL R . n 
E 5 345 VAL 345 292 292 VAL VAL R . n 
E 5 346 ILE 346 293 293 ILE ILE R . n 
E 5 347 THR 347 294 294 THR THR R . n 
E 5 348 ALA 348 295 295 ALA ALA R . n 
E 5 349 ALA 349 296 296 ALA ALA R . n 
E 5 350 TYR 350 297 297 TYR TYR R . n 
E 5 351 VAL 351 298 298 VAL VAL R . n 
E 5 352 ARG 352 299 299 ARG ARG R . n 
E 5 353 ILE 353 300 300 ILE ILE R . n 
E 5 354 LEU 354 301 301 LEU LEU R . n 
E 5 355 GLN 355 302 302 GLN GLN R . n 
E 5 356 ARG 356 303 303 ARG ARG R . n 
E 5 357 MET 357 304 304 MET MET R . n 
E 5 358 THR 358 305 305 THR THR R . n 
E 5 359 SER 359 306 306 SER SER R . n 
E 5 360 SER 360 307 307 SER SER R . n 
E 5 361 VAL 361 308 308 VAL VAL R . n 
E 5 362 ALA 362 309 309 ALA ALA R . n 
E 5 363 PRO 363 310 310 PRO PRO R . n 
E 5 364 ALA 364 311 311 ALA ALA R . n 
E 5 365 SER 365 312 312 SER SER R . n 
E 5 366 GLN 366 313 313 GLN GLN R . n 
E 5 367 ARG 367 314 314 ARG ARG R . n 
E 5 368 SER 368 315 315 SER SER R . n 
E 5 369 ILE 369 316 316 ILE ILE R . n 
E 5 370 ARG 370 317 317 ARG ARG R . n 
E 5 371 LEU 371 318 318 LEU LEU R . n 
E 5 372 ARG 372 319 319 ARG ARG R . n 
E 5 373 THR 373 320 320 THR THR R . n 
E 5 374 LYS 374 321 321 LYS LYS R . n 
E 5 375 ARG 375 322 322 ARG ARG R . n 
E 5 376 VAL 376 323 323 VAL VAL R . n 
E 5 377 THR 377 324 324 THR THR R . n 
E 5 378 ARG 378 325 325 ARG ARG R . n 
E 5 379 THR 379 326 326 THR THR R . n 
E 5 380 ALA 380 327 327 ALA ALA R . n 
E 5 381 ILE 381 328 328 ILE ILE R . n 
E 5 382 ALA 382 329 329 ALA ALA R . n 
E 5 383 ILE 383 330 330 ILE ILE R . n 
E 5 384 CYS 384 331 331 CYS CYS R . n 
E 5 385 LEU 385 332 332 LEU LEU R . n 
E 5 386 VAL 386 333 333 VAL VAL R . n 
E 5 387 PHE 387 334 334 PHE PHE R . n 
E 5 388 PHE 388 335 335 PHE PHE R . n 
E 5 389 VAL 389 336 336 VAL VAL R . n 
E 5 390 CYS 390 337 337 CYS CYS R . n 
E 5 391 TRP 391 338 338 TRP TRP R . n 
E 5 392 ALA 392 339 339 ALA ALA R . n 
E 5 393 PRO 393 340 340 PRO PRO R . n 
E 5 394 TYR 394 341 341 TYR TYR R . n 
E 5 395 TYR 395 342 342 TYR TYR R . n 
E 5 396 VAL 396 343 343 VAL VAL R . n 
E 5 397 LEU 397 344 344 LEU LEU R . n 
E 5 398 GLN 398 345 345 GLN GLN R . n 
E 5 399 LEU 399 346 346 LEU LEU R . n 
E 5 400 THR 400 347 347 THR THR R . n 
E 5 401 GLN 401 348 348 GLN GLN R . n 
E 5 402 LEU 402 349 349 LEU LEU R . n 
E 5 403 SER 403 350 350 SER SER R . n 
E 5 404 ILE 404 351 351 ILE ILE R . n 
E 5 405 SER 405 352 352 SER SER R . n 
E 5 406 ARG 406 353 353 ARG ARG R . n 
E 5 407 PRO 407 354 354 PRO PRO R . n 
E 5 408 THR 408 355 355 THR THR R . n 
E 5 409 LEU 409 356 356 LEU LEU R . n 
E 5 410 THR 410 357 357 THR THR R . n 
E 5 411 PHE 411 358 358 PHE PHE R . n 
E 5 412 VAL 412 359 359 VAL VAL R . n 
E 5 413 TYR 413 360 360 TYR TYR R . n 
E 5 414 LEU 414 361 361 LEU LEU R . n 
E 5 415 TYR 415 362 362 TYR TYR R . n 
E 5 416 ASN 416 363 363 ASN ASN R . n 
E 5 417 ALA 417 364 364 ALA ALA R . n 
E 5 418 ALA 418 365 365 ALA ALA R . n 
E 5 419 ILE 419 366 366 ILE ILE R . n 
E 5 420 SER 420 367 367 SER SER R . n 
E 5 421 LEU 421 368 368 LEU LEU R . n 
E 5 422 GLY 422 369 369 GLY GLY R . n 
E 5 423 TYR 423 370 370 TYR TYR R . n 
E 5 424 ALA 424 371 371 ALA ALA R . n 
E 5 425 ASN 425 372 372 ASN ASN R . n 
E 5 426 SER 426 373 373 SER SER R . n 
E 5 427 CYS 427 374 374 CYS CYS R . n 
E 5 428 LEU 428 375 375 LEU LEU R . n 
E 5 429 ASN 429 376 376 ASN ASN R . n 
E 5 430 PRO 430 377 377 PRO PRO R . n 
E 5 431 PHE 431 378 378 PHE PHE R . n 
E 5 432 VAL 432 379 379 VAL VAL R . n 
E 5 433 TYR 433 380 380 TYR TYR R . n 
E 5 434 ILE 434 381 381 ILE ILE R . n 
E 5 435 VAL 435 382 382 VAL VAL R . n 
E 5 436 LEU 436 383 383 LEU LEU R . n 
E 5 437 CYS 437 384 384 CYS CYS R . n 
E 5 438 GLU 438 385 385 GLU GLU R . n 
E 5 439 THR 439 386 386 THR THR R . n 
E 5 440 PHE 440 387 387 PHE PHE R . n 
E 5 441 ARG 441 388 388 ARG ARG R . n 
E 5 442 LYS 442 389 389 LYS LYS R . n 
E 5 443 ARG 443 390 390 ARG ARG R . n 
E 5 444 LEU 444 391 391 LEU LEU R . n 
E 5 445 VAL 445 392 392 VAL VAL R . n 
E 5 446 LEU 446 393 393 LEU LEU R . n 
E 5 447 SER 447 394 394 SER SER R . n 
E 5 448 VAL 448 395 395 VAL VAL R . n 
E 5 449 LYS 449 396 ?   ?   ?   R . n 
E 5 450 HIS 450 397 ?   ?   ?   R . n 
E 5 451 MET 451 398 ?   ?   ?   R . n 
E 5 452 GLY 452 399 ?   ?   ?   R . n 
E 5 453 SER 453 400 ?   ?   ?   R . n 
E 5 454 SER 454 401 ?   ?   ?   R . n 
E 5 455 GLY 455 402 ?   ?   ?   R . n 
E 5 456 GLY 456 403 ?   ?   ?   R . n 
E 5 457 GLY 457 404 ?   ?   ?   R . n 
E 5 458 GLY 458 405 ?   ?   ?   R . n 
E 5 459 SER 459 406 ?   ?   ?   R . n 
E 5 460 GLY 460 407 ?   ?   ?   R . n 
E 5 461 GLY 461 408 ?   ?   ?   R . n 
E 5 462 GLY 462 409 ?   ?   ?   R . n 
E 5 463 GLY 463 410 ?   ?   ?   R . n 
E 5 464 SER 464 411 ?   ?   ?   R . n 
E 5 465 SER 465 412 ?   ?   ?   R . n 
E 5 466 GLY 466 413 ?   ?   ?   R . n 
E 5 467 VAL 467 414 ?   ?   ?   R . n 
E 5 468 PHE 468 415 ?   ?   ?   R . n 
E 5 469 THR 469 416 ?   ?   ?   R . n 
E 5 470 LEU 470 417 ?   ?   ?   R . n 
E 5 471 GLU 471 418 ?   ?   ?   R . n 
E 5 472 ASP 472 419 ?   ?   ?   R . n 
E 5 473 PHE 473 420 ?   ?   ?   R . n 
E 5 474 VAL 474 421 ?   ?   ?   R . n 
E 5 475 GLY 475 422 ?   ?   ?   R . n 
E 5 476 ASP 476 423 ?   ?   ?   R . n 
E 5 477 TRP 477 424 ?   ?   ?   R . n 
E 5 478 GLU 478 425 ?   ?   ?   R . n 
E 5 479 GLN 479 426 ?   ?   ?   R . n 
E 5 480 THR 480 427 ?   ?   ?   R . n 
E 5 481 ALA 481 428 ?   ?   ?   R . n 
E 5 482 ALA 482 429 ?   ?   ?   R . n 
E 5 483 TYR 483 430 ?   ?   ?   R . n 
E 5 484 ASN 484 431 ?   ?   ?   R . n 
E 5 485 LEU 485 432 ?   ?   ?   R . n 
E 5 486 ASP 486 433 ?   ?   ?   R . n 
E 5 487 GLN 487 434 ?   ?   ?   R . n 
E 5 488 VAL 488 435 ?   ?   ?   R . n 
E 5 489 LEU 489 436 ?   ?   ?   R . n 
E 5 490 GLU 490 437 ?   ?   ?   R . n 
E 5 491 GLN 491 438 ?   ?   ?   R . n 
E 5 492 GLY 492 439 ?   ?   ?   R . n 
E 5 493 GLY 493 440 ?   ?   ?   R . n 
E 5 494 VAL 494 441 ?   ?   ?   R . n 
E 5 495 SER 495 442 ?   ?   ?   R . n 
E 5 496 SER 496 443 ?   ?   ?   R . n 
E 5 497 LEU 497 444 ?   ?   ?   R . n 
E 5 498 LEU 498 445 ?   ?   ?   R . n 
E 5 499 GLN 499 446 ?   ?   ?   R . n 
E 5 500 ASN 500 447 ?   ?   ?   R . n 
E 5 501 LEU 501 448 ?   ?   ?   R . n 
E 5 502 ALA 502 449 ?   ?   ?   R . n 
E 5 503 VAL 503 450 ?   ?   ?   R . n 
E 5 504 SER 504 451 ?   ?   ?   R . n 
E 5 505 VAL 505 452 ?   ?   ?   R . n 
E 5 506 THR 506 453 ?   ?   ?   R . n 
E 5 507 PRO 507 454 ?   ?   ?   R . n 
E 5 508 ILE 508 455 ?   ?   ?   R . n 
E 5 509 GLN 509 456 ?   ?   ?   R . n 
E 5 510 ARG 510 457 ?   ?   ?   R . n 
E 5 511 ILE 511 458 ?   ?   ?   R . n 
E 5 512 VAL 512 459 ?   ?   ?   R . n 
E 5 513 ARG 513 460 ?   ?   ?   R . n 
E 5 514 SER 514 461 ?   ?   ?   R . n 
E 5 515 GLY 515 462 ?   ?   ?   R . n 
E 5 516 GLU 516 463 ?   ?   ?   R . n 
E 5 517 ASN 517 464 ?   ?   ?   R . n 
E 5 518 ALA 518 465 ?   ?   ?   R . n 
E 5 519 LEU 519 466 ?   ?   ?   R . n 
E 5 520 LYS 520 467 ?   ?   ?   R . n 
E 5 521 ILE 521 468 ?   ?   ?   R . n 
E 5 522 ASP 522 469 ?   ?   ?   R . n 
E 5 523 ILE 523 470 ?   ?   ?   R . n 
E 5 524 HIS 524 471 ?   ?   ?   R . n 
E 5 525 VAL 525 472 ?   ?   ?   R . n 
E 5 526 ILE 526 473 ?   ?   ?   R . n 
E 5 527 ILE 527 474 ?   ?   ?   R . n 
E 5 528 PRO 528 475 ?   ?   ?   R . n 
E 5 529 TYR 529 476 ?   ?   ?   R . n 
E 5 530 GLU 530 477 ?   ?   ?   R . n 
E 5 531 GLY 531 478 ?   ?   ?   R . n 
E 5 532 LEU 532 479 ?   ?   ?   R . n 
E 5 533 SER 533 480 ?   ?   ?   R . n 
E 5 534 ALA 534 481 ?   ?   ?   R . n 
E 5 535 ASP 535 482 ?   ?   ?   R . n 
E 5 536 GLN 536 483 ?   ?   ?   R . n 
E 5 537 MET 537 484 ?   ?   ?   R . n 
E 5 538 ALA 538 485 ?   ?   ?   R . n 
E 5 539 GLN 539 486 ?   ?   ?   R . n 
E 5 540 ILE 540 487 ?   ?   ?   R . n 
E 5 541 GLU 541 488 ?   ?   ?   R . n 
E 5 542 GLU 542 489 ?   ?   ?   R . n 
E 5 543 VAL 543 490 ?   ?   ?   R . n 
E 5 544 PHE 544 491 ?   ?   ?   R . n 
E 5 545 LYS 545 492 ?   ?   ?   R . n 
E 5 546 VAL 546 493 ?   ?   ?   R . n 
E 5 547 VAL 547 494 ?   ?   ?   R . n 
E 5 548 TYR 548 495 ?   ?   ?   R . n 
E 5 549 PRO 549 496 ?   ?   ?   R . n 
E 5 550 VAL 550 497 ?   ?   ?   R . n 
E 5 551 ASP 551 498 ?   ?   ?   R . n 
E 5 552 ASP 552 499 ?   ?   ?   R . n 
E 5 553 HIS 553 500 ?   ?   ?   R . n 
E 5 554 HIS 554 501 ?   ?   ?   R . n 
E 5 555 PHE 555 502 ?   ?   ?   R . n 
E 5 556 LYS 556 503 ?   ?   ?   R . n 
E 5 557 VAL 557 504 ?   ?   ?   R . n 
E 5 558 ILE 558 505 ?   ?   ?   R . n 
E 5 559 LEU 559 506 ?   ?   ?   R . n 
E 5 560 PRO 560 507 ?   ?   ?   R . n 
E 5 561 TYR 561 508 ?   ?   ?   R . n 
E 5 562 GLY 562 509 ?   ?   ?   R . n 
E 5 563 THR 563 510 ?   ?   ?   R . n 
E 5 564 LEU 564 511 ?   ?   ?   R . n 
E 5 565 VAL 565 512 ?   ?   ?   R . n 
E 5 566 ILE 566 513 ?   ?   ?   R . n 
E 5 567 ASP 567 514 ?   ?   ?   R . n 
E 5 568 GLY 568 515 ?   ?   ?   R . n 
E 5 569 VAL 569 516 ?   ?   ?   R . n 
E 5 570 THR 570 517 ?   ?   ?   R . n 
E 5 571 PRO 571 518 ?   ?   ?   R . n 
E 5 572 ASN 572 519 ?   ?   ?   R . n 
E 5 573 MET 573 520 ?   ?   ?   R . n 
E 5 574 LEU 574 521 ?   ?   ?   R . n 
E 5 575 ASN 575 522 ?   ?   ?   R . n 
E 5 576 TYR 576 523 ?   ?   ?   R . n 
E 5 577 PHE 577 524 ?   ?   ?   R . n 
E 5 578 GLY 578 525 ?   ?   ?   R . n 
E 5 579 ARG 579 526 ?   ?   ?   R . n 
E 5 580 PRO 580 527 ?   ?   ?   R . n 
E 5 581 TYR 581 528 ?   ?   ?   R . n 
E 5 582 GLU 582 529 ?   ?   ?   R . n 
E 5 583 GLY 583 530 ?   ?   ?   R . n 
E 5 584 ILE 584 531 ?   ?   ?   R . n 
E 5 585 ALA 585 532 ?   ?   ?   R . n 
E 5 586 VAL 586 533 ?   ?   ?   R . n 
E 5 587 PHE 587 534 ?   ?   ?   R . n 
E 5 588 ASP 588 535 ?   ?   ?   R . n 
E 5 589 GLY 589 536 ?   ?   ?   R . n 
E 5 590 LYS 590 537 ?   ?   ?   R . n 
E 5 591 LYS 591 538 ?   ?   ?   R . n 
E 5 592 ILE 592 539 ?   ?   ?   R . n 
E 5 593 THR 593 540 ?   ?   ?   R . n 
E 5 594 VAL 594 541 ?   ?   ?   R . n 
E 5 595 THR 595 542 ?   ?   ?   R . n 
E 5 596 GLY 596 543 ?   ?   ?   R . n 
E 5 597 THR 597 544 ?   ?   ?   R . n 
E 5 598 LEU 598 545 ?   ?   ?   R . n 
E 5 599 TRP 599 546 ?   ?   ?   R . n 
E 5 600 ASN 600 547 ?   ?   ?   R . n 
E 5 601 GLY 601 548 ?   ?   ?   R . n 
E 5 602 ASN 602 549 ?   ?   ?   R . n 
E 5 603 LYS 603 550 ?   ?   ?   R . n 
E 5 604 ILE 604 551 ?   ?   ?   R . n 
E 5 605 ILE 605 552 ?   ?   ?   R . n 
E 5 606 ASP 606 553 ?   ?   ?   R . n 
E 5 607 GLU 607 554 ?   ?   ?   R . n 
E 5 608 ARG 608 555 ?   ?   ?   R . n 
E 5 609 LEU 609 556 ?   ?   ?   R . n 
E 5 610 ILE 610 557 ?   ?   ?   R . n 
E 5 611 THR 611 558 ?   ?   ?   R . n 
E 5 612 PRO 612 559 ?   ?   ?   R . n 
E 5 613 ASP 613 560 ?   ?   ?   R . n 
E 5 614 GLY 614 561 ?   ?   ?   R . n 
E 5 615 SER 615 562 ?   ?   ?   R . n 
E 5 616 MET 616 563 ?   ?   ?   R . n 
E 5 617 LEU 617 564 ?   ?   ?   R . n 
E 5 618 PHE 618 565 ?   ?   ?   R . n 
E 5 619 ARG 619 566 ?   ?   ?   R . n 
E 5 620 VAL 620 567 ?   ?   ?   R . n 
E 5 621 THR 621 568 ?   ?   ?   R . n 
E 5 622 ILE 622 569 ?   ?   ?   R . n 
E 5 623 ASN 623 570 ?   ?   ?   R . n 
E 5 624 SER 624 571 ?   ?   ?   R . n 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 A GLU 43  ? CG  ? A GLU 43  CG  
2   1 Y 1 A GLU 43  ? CD  ? A GLU 43  CD  
3   1 Y 1 A GLU 43  ? OE1 ? A GLU 43  OE1 
4   1 Y 1 A GLU 43  ? OE2 ? A GLU 43  OE2 
5   1 Y 1 A THR 48  ? OG1 ? A THR 48  OG1 
6   1 Y 1 A THR 48  ? CG2 ? A THR 48  CG2 
7   1 Y 1 A LYS 51  ? CG  ? A LYS 51  CG  
8   1 Y 1 A LYS 51  ? CD  ? A LYS 51  CD  
9   1 Y 1 A LYS 51  ? CE  ? A LYS 51  CE  
10  1 Y 1 A LYS 51  ? NZ  ? A LYS 51  NZ  
11  1 Y 1 A LYS 54  ? CG  ? A LYS 54  CG  
12  1 Y 1 A LYS 54  ? CD  ? A LYS 54  CD  
13  1 Y 1 A LYS 54  ? CE  ? A LYS 54  CE  
14  1 Y 1 A LYS 54  ? NZ  ? A LYS 54  NZ  
15  1 Y 1 A THR 182 ? OG1 ? A THR 182 OG1 
16  1 Y 1 A THR 182 ? CG2 ? A THR 182 CG2 
17  1 Y 1 A ARG 205 ? CG  ? A ARG 205 CG  
18  1 Y 1 A ARG 205 ? CD  ? A ARG 205 CD  
19  1 Y 1 A ARG 205 ? NE  ? A ARG 205 NE  
20  1 Y 1 A ARG 205 ? CZ  ? A ARG 205 CZ  
21  1 Y 1 A ARG 205 ? NH1 ? A ARG 205 NH1 
22  1 Y 1 A ARG 205 ? NH2 ? A ARG 205 NH2 
23  1 Y 1 A GLU 236 ? CG  ? A GLU 236 CG  
24  1 Y 1 A GLU 236 ? CD  ? A GLU 236 CD  
25  1 Y 1 A GLU 236 ? OE1 ? A GLU 236 OE1 
26  1 Y 1 A GLU 236 ? OE2 ? A GLU 236 OE2 
27  1 Y 1 A ASP 237 ? CG  ? A ASP 237 CG  
28  1 Y 1 A ASP 237 ? OD1 ? A ASP 237 OD1 
29  1 Y 1 A ASP 237 ? OD2 ? A ASP 237 OD2 
30  1 Y 1 A GLU 238 ? CG  ? A GLU 238 CG  
31  1 Y 1 A GLU 238 ? CD  ? A GLU 238 CD  
32  1 Y 1 A GLU 238 ? OE1 ? A GLU 238 OE1 
33  1 Y 1 A GLU 238 ? OE2 ? A GLU 238 OE2 
34  1 Y 1 A GLU 239 ? CG  ? A GLU 239 CG  
35  1 Y 1 A GLU 239 ? CD  ? A GLU 239 CD  
36  1 Y 1 A GLU 239 ? OE1 ? A GLU 239 OE1 
37  1 Y 1 A GLU 239 ? OE2 ? A GLU 239 OE2 
38  1 Y 1 A LYS 248 ? CG  ? A LYS 248 CG  
39  1 Y 1 A LYS 248 ? CD  ? A LYS 248 CD  
40  1 Y 1 A LYS 248 ? CE  ? A LYS 248 CE  
41  1 Y 1 A LYS 248 ? NZ  ? A LYS 248 NZ  
42  1 Y 1 A LYS 271 ? CG  ? A LYS 271 CG  
43  1 Y 1 A LYS 271 ? CD  ? A LYS 271 CD  
44  1 Y 1 A LYS 271 ? CE  ? A LYS 271 CE  
45  1 Y 1 A LYS 271 ? NZ  ? A LYS 271 NZ  
46  1 Y 1 A LYS 277 ? CG  ? A LYS 277 CG  
47  1 Y 1 A LYS 277 ? CD  ? A LYS 277 CD  
48  1 Y 1 A LYS 277 ? CE  ? A LYS 277 CE  
49  1 Y 1 A LYS 277 ? NZ  ? A LYS 277 NZ  
50  1 Y 1 A LYS 279 ? CG  ? A LYS 279 CG  
51  1 Y 1 A LYS 279 ? CD  ? A LYS 279 CD  
52  1 Y 1 A LYS 279 ? CE  ? A LYS 279 CE  
53  1 Y 1 A LYS 279 ? NZ  ? A LYS 279 NZ  
54  1 Y 1 A LYS 280 ? CG  ? A LYS 280 CG  
55  1 Y 1 A LYS 280 ? CD  ? A LYS 280 CD  
56  1 Y 1 A LYS 280 ? CE  ? A LYS 280 CE  
57  1 Y 1 A LYS 280 ? NZ  ? A LYS 280 NZ  
58  1 Y 1 A GLU 289 ? CG  ? A GLU 289 CG  
59  1 Y 1 A GLU 289 ? CD  ? A GLU 289 CD  
60  1 Y 1 A GLU 289 ? OE1 ? A GLU 289 OE1 
61  1 Y 1 A GLU 289 ? OE2 ? A GLU 289 OE2 
62  1 Y 1 A GLU 298 ? CG  ? A GLU 298 CG  
63  1 Y 1 A GLU 298 ? CD  ? A GLU 298 CD  
64  1 Y 1 A GLU 298 ? OE1 ? A GLU 298 OE1 
65  1 Y 1 A GLU 298 ? OE2 ? A GLU 298 OE2 
66  1 Y 1 R TYR 107 ? CG  ? E TYR 160 CG  
67  1 Y 1 R TYR 107 ? CD1 ? E TYR 160 CD1 
68  1 Y 1 R TYR 107 ? CD2 ? E TYR 160 CD2 
69  1 Y 1 R TYR 107 ? CE1 ? E TYR 160 CE1 
70  1 Y 1 R TYR 107 ? CE2 ? E TYR 160 CE2 
71  1 Y 1 R TYR 107 ? CZ  ? E TYR 160 CZ  
72  1 Y 1 R TYR 107 ? OH  ? E TYR 160 OH  
73  1 Y 1 R ILE 108 ? CG1 ? E ILE 161 CG1 
74  1 Y 1 R ILE 108 ? CG2 ? E ILE 161 CG2 
75  1 Y 1 R ILE 108 ? CD1 ? E ILE 161 CD1 
76  1 Y 1 R ASN 109 ? CG  ? E ASN 162 CG  
77  1 Y 1 R ASN 109 ? OD1 ? E ASN 162 OD1 
78  1 Y 1 R ASN 109 ? ND2 ? E ASN 162 ND2 
79  1 Y 1 R ILE 110 ? CG1 ? E ILE 163 CG1 
80  1 Y 1 R ILE 110 ? CG2 ? E ILE 163 CG2 
81  1 Y 1 R ILE 110 ? CD1 ? E ILE 163 CD1 
82  1 Y 1 R ILE 111 ? CG1 ? E ILE 164 CG1 
83  1 Y 1 R ILE 111 ? CG2 ? E ILE 164 CG2 
84  1 Y 1 R ILE 111 ? CD1 ? E ILE 164 CD1 
85  1 Y 1 R LYS 136 ? CG  ? E LYS 189 CG  
86  1 Y 1 R LYS 136 ? CD  ? E LYS 189 CD  
87  1 Y 1 R LYS 136 ? CE  ? E LYS 189 CE  
88  1 Y 1 R LYS 136 ? NZ  ? E LYS 189 NZ  
89  1 Y 1 R LYS 137 ? CG  ? E LYS 190 CG  
90  1 Y 1 R LYS 137 ? CD  ? E LYS 190 CD  
91  1 Y 1 R LYS 137 ? CE  ? E LYS 190 CE  
92  1 Y 1 R LYS 137 ? NZ  ? E LYS 190 NZ  
93  1 Y 1 R ASN 175 ? CG  ? E ASN 228 CG  
94  1 Y 1 R ASN 175 ? OD1 ? E ASN 228 OD1 
95  1 Y 1 R ASN 175 ? ND2 ? E ASN 228 ND2 
96  1 Y 1 R ARG 314 ? CG  ? E ARG 367 CG  
97  1 Y 1 R ARG 314 ? CD  ? E ARG 367 CD  
98  1 Y 1 R ARG 314 ? NE  ? E ARG 367 NE  
99  1 Y 1 R ARG 314 ? CZ  ? E ARG 367 CZ  
100 1 Y 1 R ARG 314 ? NH1 ? E ARG 367 NH1 
101 1 Y 1 R ARG 314 ? NH2 ? E ARG 367 NH2 
102 1 Y 1 R ARG 317 ? CG  ? E ARG 370 CG  
103 1 Y 1 R ARG 317 ? CD  ? E ARG 370 CD  
104 1 Y 1 R ARG 317 ? NE  ? E ARG 370 NE  
105 1 Y 1 R ARG 317 ? CZ  ? E ARG 370 CZ  
106 1 Y 1 R ARG 317 ? NH1 ? E ARG 370 NH1 
107 1 Y 1 R ARG 317 ? NH2 ? E ARG 370 NH2 
108 1 Y 1 R ARG 353 ? CG  ? E ARG 406 CG  
109 1 Y 1 R ARG 353 ? CD  ? E ARG 406 CD  
110 1 Y 1 R ARG 353 ? NE  ? E ARG 406 NE  
111 1 Y 1 R ARG 353 ? CZ  ? E ARG 406 CZ  
112 1 Y 1 R ARG 353 ? NH1 ? E ARG 406 NH1 
113 1 Y 1 R ARG 353 ? NH2 ? E ARG 406 NH2 
114 1 Y 1 R GLU 385 ? CG  ? E GLU 438 CG  
115 1 Y 1 R GLU 385 ? CD  ? E GLU 438 CD  
116 1 Y 1 R GLU 385 ? OE1 ? E GLU 438 OE1 
117 1 Y 1 R GLU 385 ? OE2 ? E GLU 438 OE2 
118 1 Y 1 R LYS 389 ? CG  ? E LYS 442 CG  
119 1 Y 1 R LYS 389 ? CD  ? E LYS 442 CD  
120 1 Y 1 R LYS 389 ? CE  ? E LYS 442 CE  
121 1 Y 1 R LYS 389 ? NZ  ? E LYS 442 NZ  
122 1 Y 1 R ARG 390 ? CG  ? E ARG 443 CG  
123 1 Y 1 R ARG 390 ? CD  ? E ARG 443 CD  
124 1 Y 1 R ARG 390 ? NE  ? E ARG 443 NE  
125 1 Y 1 R ARG 390 ? CZ  ? E ARG 443 CZ  
126 1 Y 1 R ARG 390 ? NH1 ? E ARG 443 NH1 
127 1 Y 1 R ARG 390 ? NH2 ? E ARG 443 NH2 
128 1 Y 1 R LEU 393 ? CG  ? E LEU 446 CG  
129 1 Y 1 R LEU 393 ? CD1 ? E LEU 446 CD1 
130 1 Y 1 R LEU 393 ? CD2 ? E LEU 446 CD2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8WWI 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8WWI 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8WWI 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 8WWI 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.001 ? 8992  ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.402 ? 12214 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 8.183 ? 3165  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.039 ? 1406  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.003 ? 1546  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8WWI 
_struct.title                        'MCHR1-Gi complex,S3 state' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8WWI 
_struct_keywords.text            'Apo complex GPCR MCHR1, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP GNAI1_HUMAN P63096 ? 1 
;MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQS
IIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLD
RIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM
NRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIY
THFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF
;
1   
2 UNP GBB1_HUMAN  P62873 ? 2 
;SELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLII
WDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSS
GDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAF
ATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVT
DDGMAVATGSWDSFLKIWN
;
2   
3 UNP GBG2_HUMAN  P59768 ? 3 MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL 1   
4 PDB 8WWI        8WWI   ? 4 ? 1   
5 PDB 8WWI        8WWI   ? 5 ? 1   
6 UNP MCHR1_HUMAN Q99705 ? 5 
;MSVGAMKKGVGRAVGLGGGSGCQATEEDPLPNCGACAPGQGGRRWRLPQPAWVEGSSARLWEQATGTGWMDLEASLLPTG
PNASNTSDGPDNLTSAGSPPRTGSISYINIIMPSVFGTICLLGIIGNSTVIFAVVKKSKLHWCNNVPDIFIINLSVVDLL
FLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMAIDRYLATVHPISSTKFRKPSVATLVICLLWALS
FISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVRILQRMTSSVAPASQRSIRLRT
KRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVK
;
1   
7 PDB 8WWI        8WWI   ? 5 ? 450 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8WWI A 1   ? 354 ? P63096 1   ? 354 ? 1   354 
2 2 8WWI B 12  ? 350 ? P62873 2   ? 340 ? 2   340 
3 3 8WWI C 1   ? 71  ? P59768 1   ? 71  ? 1   71  
4 4 8WWI E 1   ? 255 ? 8WWI   1   ? 255 ? 1   255 
5 5 8WWI R 1   ? 53  ? 8WWI   -52 ? 0   ? -52 0   
6 6 8WWI R 54  ? 449 ? Q99705 1   ? 396 ? 1   396 
7 7 8WWI R 450 ? 624 ? 8WWI   397 ? 571 ? 397 571 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8WWI ASN A 47  ? UNP P63096 SER 47  conflict                47  1  
1 8WWI ALA A 203 ? UNP P63096 GLY 203 conflict                203 2  
1 8WWI ALA A 245 ? UNP P63096 GLU 245 conflict                245 3  
1 8WWI SER A 326 ? UNP P63096 ALA 326 conflict                326 4  
2 8WWI MET B 1   ? UNP P62873 ?   ?   'initiating methionine' -9  5  
2 8WWI HIS B 2   ? UNP P62873 ?   ?   'expression tag'        -8  6  
2 8WWI HIS B 3   ? UNP P62873 ?   ?   'expression tag'        -7  7  
2 8WWI HIS B 4   ? UNP P62873 ?   ?   'expression tag'        -6  8  
2 8WWI HIS B 5   ? UNP P62873 ?   ?   'expression tag'        -5  9  
2 8WWI HIS B 6   ? UNP P62873 ?   ?   'expression tag'        -4  10 
2 8WWI HIS B 7   ? UNP P62873 ?   ?   'expression tag'        -3  11 
2 8WWI GLY B 8   ? UNP P62873 ?   ?   'expression tag'        -2  12 
2 8WWI SER B 9   ? UNP P62873 ?   ?   'expression tag'        -1  13 
2 8WWI SER B 10  ? UNP P62873 ?   ?   'expression tag'        0   14 
2 8WWI GLY B 11  ? UNP P62873 ?   ?   'expression tag'        1   15 
2 8WWI GLY B 351 ? UNP P62873 ?   ?   'expression tag'        341 16 
2 8WWI SER B 352 ? UNP P62873 ?   ?   'expression tag'        342 17 
2 8WWI SER B 353 ? UNP P62873 ?   ?   'expression tag'        343 18 
2 8WWI GLY B 354 ? UNP P62873 ?   ?   'expression tag'        344 19 
2 8WWI GLY B 355 ? UNP P62873 ?   ?   'expression tag'        345 20 
2 8WWI GLY B 356 ? UNP P62873 ?   ?   'expression tag'        346 21 
2 8WWI GLY B 357 ? UNP P62873 ?   ?   'expression tag'        347 22 
2 8WWI SER B 358 ? UNP P62873 ?   ?   'expression tag'        348 23 
2 8WWI GLY B 359 ? UNP P62873 ?   ?   'expression tag'        349 24 
2 8WWI GLY B 360 ? UNP P62873 ?   ?   'expression tag'        350 25 
2 8WWI GLY B 361 ? UNP P62873 ?   ?   'expression tag'        351 26 
2 8WWI GLY B 362 ? UNP P62873 ?   ?   'expression tag'        352 27 
2 8WWI SER B 363 ? UNP P62873 ?   ?   'expression tag'        353 28 
2 8WWI SER B 364 ? UNP P62873 ?   ?   'expression tag'        354 29 
2 8WWI GLY B 365 ? UNP P62873 ?   ?   'expression tag'        355 30 
2 8WWI VAL B 366 ? UNP P62873 ?   ?   'expression tag'        356 31 
2 8WWI SER B 367 ? UNP P62873 ?   ?   'expression tag'        357 32 
2 8WWI GLY B 368 ? UNP P62873 ?   ?   'expression tag'        358 33 
2 8WWI TRP B 369 ? UNP P62873 ?   ?   'expression tag'        359 34 
2 8WWI ARG B 370 ? UNP P62873 ?   ?   'expression tag'        360 35 
2 8WWI LEU B 371 ? UNP P62873 ?   ?   'expression tag'        361 36 
2 8WWI PHE B 372 ? UNP P62873 ?   ?   'expression tag'        362 37 
2 8WWI LYS B 373 ? UNP P62873 ?   ?   'expression tag'        363 38 
2 8WWI LYS B 374 ? UNP P62873 ?   ?   'expression tag'        364 39 
2 8WWI ILE B 375 ? UNP P62873 ?   ?   'expression tag'        365 40 
2 8WWI SER B 376 ? UNP P62873 ?   ?   'expression tag'        366 41 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   pentameric 
_pdbx_struct_assembly.oligomeric_count     5 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 6   ? ARG A 32  ? SER A 6   ARG A 32  1 ? 27 
HELX_P HELX_P2  AA2 GLY A 45  ? MET A 53  ? GLY A 45  MET A 53  1 ? 9  
HELX_P HELX_P3  AA3 GLU A 207 ? ILE A 212 ? GLU A 207 ILE A 212 1 ? 6  
HELX_P HELX_P4  AA4 HIS A 213 ? GLU A 216 ? HIS A 213 GLU A 216 5 ? 4  
HELX_P HELX_P5  AA5 ASN A 241 ? ASN A 255 ? ASN A 241 ASN A 255 1 ? 15 
HELX_P HELX_P6  AA6 ASN A 256 ? THR A 260 ? ASN A 256 THR A 260 5 ? 5  
HELX_P HELX_P7  AA7 LYS A 270 ? SER A 281 ? LYS A 270 SER A 281 1 ? 12 
HELX_P HELX_P8  AA8 PRO A 282 ? CYS A 286 ? PRO A 282 CYS A 286 5 ? 5  
HELX_P HELX_P9  AA9 THR A 295 ? LEU A 310 ? THR A 295 LEU A 310 1 ? 16 
HELX_P HELX_P10 AB1 LYS A 330 ? CYS A 351 ? LYS A 330 CYS A 351 1 ? 22 
HELX_P HELX_P11 AB2 GLU B 13  ? CYS B 35  ? GLU B 3   CYS B 25  1 ? 23 
HELX_P HELX_P12 AB3 THR B 39  ? THR B 44  ? THR B 29  THR B 34  1 ? 6  
HELX_P HELX_P13 AB4 ALA C 7   ? ASN C 24  ? ALA C 7   ASN C 24  1 ? 18 
HELX_P HELX_P14 AB5 LYS C 29  ? HIS C 44  ? LYS C 29  HIS C 44  1 ? 16 
HELX_P HELX_P15 AB6 PRO C 55  ? ASN C 59  ? PRO C 55  ASN C 59  5 ? 5  
HELX_P HELX_P16 AB7 ALA D 28  ? PHE D 32  ? ALA E 28  PHE E 32  5 ? 5  
HELX_P HELX_P17 AB8 ARG D 87  ? THR D 91  ? ARG E 87  THR E 91  5 ? 5  
HELX_P HELX_P18 AB9 ILE E 161 ? LYS E 190 ? ILE R 108 LYS R 137 1 ? 30 
HELX_P HELX_P19 AC1 ASN E 198 ? GLY E 217 ? ASN R 145 GLY R 164 1 ? 20 
HELX_P HELX_P20 AC2 MET E 218 ? GLY E 227 ? MET R 165 GLY R 174 1 ? 10 
HELX_P HELX_P21 AC3 PHE E 233 ? HIS E 269 ? PHE R 180 HIS R 216 1 ? 37 
HELX_P HELX_P22 AC4 ILE E 271 ? PHE E 276 ? ILE R 218 PHE R 223 5 ? 6  
HELX_P HELX_P23 AC5 LYS E 278 ? ILE E 297 ? LYS R 225 ILE R 244 1 ? 20 
HELX_P HELX_P24 AC6 ILE E 297 ? TYR E 303 ? ILE R 244 TYR R 250 1 ? 7  
HELX_P HELX_P25 AC7 ASN E 322 ? PHE E 339 ? ASN R 269 PHE R 286 1 ? 18 
HELX_P HELX_P26 AC8 PHE E 339 ? ARG E 356 ? PHE R 286 ARG R 303 1 ? 18 
HELX_P HELX_P27 AC9 GLN E 366 ? ILE E 404 ? GLN R 313 ILE R 351 1 ? 39 
HELX_P HELX_P28 AD1 THR E 408 ? CYS E 437 ? THR R 355 CYS R 384 1 ? 30 
HELX_P HELX_P29 AD2 CYS E 437 ? VAL E 448 ? CYS R 384 VAL R 395 1 ? 12 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? D CYS 22  SG ? ? ? 1_555 D CYS 96  SG ? ? E CYS 22  E CYS 96  1_555 ? ? ? ? ? ? ? 2.030 ? ? 
disulf2 disulf ? ? D CYS 159 SG ? ? ? 1_555 D CYS 229 SG ? ? E CYS 159 E CYS 229 1_555 ? ? ? ? ? ? ? 2.032 ? ? 
disulf3 disulf ? ? E CYS 238 SG ? ? ? 1_555 E CYS 316 SG ? ? R CYS 185 R CYS 263 1_555 ? ? ? ? ? ? ? 2.031 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS D 22  ? CYS D 96  ? CYS E 22  ? 1_555 CYS E 96  ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS D 159 ? CYS D 229 ? CYS E 159 ? 1_555 CYS E 229 ? 1_555 SG SG . . . None 'Disulfide bridge' 
3 CYS E 238 ? CYS E 316 ? CYS R 185 ? 1_555 CYS R 263 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          TYR 
_struct_mon_prot_cis.label_seq_id           235 
_struct_mon_prot_cis.label_asym_id          D 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           TYR 
_struct_mon_prot_cis.auth_seq_id            235 
_struct_mon_prot_cis.auth_asym_id           E 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    236 
_struct_mon_prot_cis.pdbx_label_asym_id_2   D 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     236 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    E 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       4.06 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 6 ? 
AA2 ? 4 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 4 ? 
AA6 ? 4 ? 
AA7 ? 4 ? 
AA8 ? 4 ? 
AA9 ? 4 ? 
AB1 ? 6 ? 
AB2 ? 4 ? 
AB3 ? 4 ? 
AB4 ? 6 ? 
AB5 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? parallel      
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB1 4 5 ? anti-parallel 
AB1 5 6 ? anti-parallel 
AB2 1 2 ? parallel      
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB4 1 2 ? parallel      
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB4 4 5 ? anti-parallel 
AB4 5 6 ? anti-parallel 
AB5 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 VAL A 185 ? THR A 190 ? VAL A 185 THR A 190 
AA1 2 HIS A 195 ? ASP A 200 ? HIS A 195 ASP A 200 
AA1 3 VAL A 34  ? GLY A 40  ? VAL A 34  GLY A 40  
AA1 4 ALA A 220 ? ALA A 226 ? ALA A 220 ALA A 226 
AA1 5 SER A 263 ? ASN A 269 ? SER A 263 ASN A 269 
AA1 6 ILE A 319 ? HIS A 322 ? ILE A 319 HIS A 322 
AA2 1 ARG B 56  ? LEU B 61  ? ARG B 46  LEU B 51  
AA2 2 LEU B 346 ? ASN B 350 ? LEU B 336 ASN B 340 
AA2 3 VAL B 337 ? GLY B 340 ? VAL B 327 GLY B 330 
AA2 4 CYS B 327 ? VAL B 330 ? CYS B 317 VAL B 320 
AA3 1 ILE B 68  ? TRP B 73  ? ILE B 58  TRP B 63  
AA3 2 LEU B 79  ? SER B 84  ? LEU B 69  SER B 74  
AA3 3 LYS B 88  ? ASP B 93  ? LYS B 78  ASP B 83  
AA3 4 ASN B 98  ? PRO B 104 ? ASN B 88  PRO B 94  
AA4 1 VAL B 110 ? TYR B 115 ? VAL B 100 TYR B 105 
AA4 2 TYR B 121 ? GLY B 126 ? TYR B 111 GLY B 116 
AA4 3 CYS B 131 ? ASN B 135 ? CYS B 121 ASN B 125 
AA4 4 ARG B 144 ? LEU B 149 ? ARG B 134 LEU B 139 
AA5 1 LEU B 156 ? PHE B 161 ? LEU B 146 PHE B 151 
AA5 2 GLN B 166 ? SER B 171 ? GLN B 156 SER B 161 
AA5 3 CYS B 176 ? ASP B 180 ? CYS B 166 ASP B 170 
AA5 4 GLN B 185 ? PHE B 190 ? GLN B 175 PHE B 180 
AA6 1 VAL B 197 ? LEU B 202 ? VAL B 187 LEU B 192 
AA6 2 LEU B 208 ? ALA B 213 ? LEU B 198 ALA B 203 
AA6 3 SER B 217 ? ASP B 222 ? SER B 207 ASP B 212 
AA6 4 CYS B 228 ? THR B 233 ? CYS B 218 THR B 223 
AA7 1 ILE B 239 ? PHE B 244 ? ILE B 229 PHE B 234 
AA7 2 ALA B 250 ? SER B 255 ? ALA B 240 SER B 245 
AA7 3 THR B 259 ? ASP B 264 ? THR B 249 ASP B 254 
AA7 4 GLN B 269 ? SER B 275 ? GLN B 259 SER B 265 
AA8 1 ILE B 283 ? PHE B 288 ? ILE B 273 PHE B 278 
AA8 2 LEU B 294 ? TYR B 299 ? LEU B 284 TYR B 289 
AA8 3 CYS B 304 ? ASP B 308 ? CYS B 294 ASP B 298 
AA8 4 ASP B 313 ? LEU B 318 ? ASP B 303 LEU B 308 
AA9 1 GLN D 3   ? SER D 7   ? GLN E 3   SER E 7   
AA9 2 GLY D 16  ? SER D 25  ? GLY E 16  SER E 25  
AA9 3 THR D 78  ? LEU D 86  ? THR E 78  LEU E 86  
AA9 4 PHE D 68  ? ASP D 73  ? PHE E 68  ASP E 73  
AB1 1 LEU D 11  ? VAL D 12  ? LEU E 11  VAL E 12  
AB1 2 THR D 115 ? VAL D 119 ? THR E 115 VAL E 119 
AB1 3 ALA D 92  ? SER D 99  ? ALA E 92  SER E 99  
AB1 4 GLY D 33  ? GLN D 39  ? GLY E 33  GLN E 39  
AB1 5 LEU D 45  ? ILE D 51  ? LEU E 45  ILE E 51  
AB1 6 ILE D 58  ? TYR D 60  ? ILE E 58  TYR E 60  
AB2 1 LEU D 11  ? VAL D 12  ? LEU E 11  VAL E 12  
AB2 2 THR D 115 ? VAL D 119 ? THR E 115 VAL E 119 
AB2 3 ALA D 92  ? SER D 99  ? ALA E 92  SER E 99  
AB2 4 PHE D 110 ? TRP D 111 ? PHE E 110 TRP E 111 
AB3 1 MET D 140 ? THR D 141 ? MET E 140 THR E 141 
AB3 2 VAL D 155 ? SER D 161 ? VAL E 155 SER E 161 
AB3 3 ALA D 211 ? ILE D 216 ? ALA E 211 ILE E 216 
AB3 4 PHE D 203 ? SER D 208 ? PHE E 203 SER E 208 
AB4 1 SER D 146 ? PRO D 148 ? SER E 146 PRO E 148 
AB4 2 THR D 243 ? GLU D 246 ? THR E 243 GLU E 246 
AB4 3 VAL D 226 ? GLN D 231 ? VAL E 226 GLN E 231 
AB4 4 LEU D 174 ? GLN D 179 ? LEU E 174 GLN E 179 
AB4 5 PRO D 185 ? TYR D 190 ? PRO E 185 TYR E 190 
AB4 6 ASN D 194 ? LEU D 195 ? ASN E 194 LEU E 195 
AB5 1 ALA E 304 ? PRO E 308 ? ALA R 251 PRO R 255 
AB5 2 VAL E 314 ? ILE E 318 ? VAL R 261 ILE R 265 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N THR A 187 ? N THR A 187 O MET A 198 ? O MET A 198 
AA1 2 3 O LYS A 197 ? O LYS A 197 N LEU A 36  ? N LEU A 36  
AA1 3 4 N LEU A 39  ? N LEU A 39  O ILE A 222 ? O ILE A 222 
AA1 4 5 N ILE A 221 ? N ILE A 221 O ILE A 265 ? O ILE A 265 
AA1 5 6 N LEU A 266 ? N LEU A 266 O TYR A 320 ? O TYR A 320 
AA2 1 2 N LEU B 61  ? N LEU B 51  O LEU B 346 ? O LEU B 336 
AA2 2 3 O TRP B 349 ? O TRP B 339 N VAL B 337 ? N VAL B 327 
AA2 3 4 O GLY B 340 ? O GLY B 330 N CYS B 327 ? N CYS B 317 
AA3 1 2 N ALA B 70  ? N ALA B 60  O ALA B 83  ? O ALA B 73  
AA3 2 3 N LEU B 80  ? N LEU B 70  O TRP B 92  ? O TRP B 82  
AA3 3 4 N LEU B 89  ? N LEU B 79  O ILE B 103 ? O ILE B 93  
AA4 1 2 N ALA B 114 ? N ALA B 104 O ALA B 123 ? O ALA B 113 
AA4 2 3 N VAL B 122 ? N VAL B 112 O TYR B 134 ? O TYR B 124 
AA4 3 4 N ILE B 133 ? N ILE B 123 O ARG B 147 ? O ARG B 137 
AA5 1 2 N CYS B 158 ? N CYS B 148 O SER B 170 ? O SER B 160 
AA5 2 3 N ILE B 167 ? N ILE B 157 O TRP B 179 ? O TRP B 169 
AA5 3 4 N CYS B 176 ? N CYS B 166 O PHE B 190 ? O PHE B 180 
AA6 1 2 N MET B 198 ? N MET B 188 O GLY B 212 ? O GLY B 202 
AA6 2 3 N PHE B 209 ? N PHE B 199 O TRP B 221 ? O TRP B 211 
AA6 3 4 N ALA B 218 ? N ALA B 208 O PHE B 232 ? O PHE B 222 
AA7 1 2 N ASN B 240 ? N ASN B 230 O GLY B 254 ? O GLY B 244 
AA7 2 3 N THR B 253 ? N THR B 243 O ARG B 261 ? O ARG B 251 
AA7 3 4 N CYS B 260 ? N CYS B 250 O TYR B 274 ? O TYR B 264 
AA8 1 2 N THR B 284 ? N THR B 274 O GLY B 298 ? O GLY B 288 
AA8 2 3 N LEU B 295 ? N LEU B 285 O TRP B 307 ? O TRP B 297 
AA8 3 4 N CYS B 304 ? N CYS B 294 O LEU B 318 ? O LEU B 308 
AA9 1 2 N GLN D 3   ? N GLN E 3   O SER D 25  ? O SER E 25  
AA9 2 3 N GLY D 16  ? N GLY E 16  O LEU D 86  ? O LEU E 86  
AA9 3 4 O GLN D 82  ? O GLN E 82  N THR D 69  ? N THR E 69  
AB1 1 2 N VAL D 12  ? N VAL E 12  O THR D 118 ? O THR E 118 
AB1 2 3 O THR D 115 ? O THR E 115 N TYR D 94  ? N TYR E 94  
AB1 3 4 O TYR D 95  ? O TYR E 95  N VAL D 37  ? N VAL E 37  
AB1 4 5 N ARG D 38  ? N ARG E 38  O GLU D 46  ? O GLU E 46  
AB1 5 6 N TYR D 50  ? N TYR E 50  O TYR D 59  ? O TYR E 59  
AB2 1 2 N VAL D 12  ? N VAL E 12  O THR D 118 ? O THR E 118 
AB2 2 3 O THR D 115 ? O THR E 115 N TYR D 94  ? N TYR E 94  
AB2 3 4 N ARG D 98  ? N ARG E 98  O PHE D 110 ? O PHE E 110 
AB3 1 2 N THR D 141 ? N THR E 141 O ARG D 160 ? O ARG E 160 
AB3 2 3 N VAL D 155 ? N VAL E 155 O ILE D 216 ? O ILE E 216 
AB3 3 4 O THR D 213 ? O THR E 213 N SER D 206 ? N SER E 206 
AB4 1 2 N VAL D 147 ? N VAL E 147 O LYS D 244 ? O LYS E 244 
AB4 2 3 O THR D 243 ? O THR E 243 N TYR D 227 ? N TYR E 227 
AB4 3 4 O MET D 230 ? O MET E 230 N TYR D 175 ? N TYR E 175 
AB4 4 5 N TRP D 176 ? N TRP E 176 O LEU D 188 ? O LEU E 188 
AB4 5 6 N TYR D 190 ? N TYR E 190 O ASN D 194 ? O ASN E 194 
AB5 1 2 N ILE E 307 ? N ILE R 254 O GLY E 315 ? O GLY R 262 
# 
_pdbx_entry_details.entry_id                   8WWI 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 O  B ILE 58  ? ? OG B SER 316 ? ? 2.09 
2 1 OH A TYR 290 ? ? O  A SER 293 ? ? 2.12 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 ASP A 229 ? ? -90.40 52.52  
2 1 MET E 192 ? ? 73.26  -15.14 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8WWI 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8WWI 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.43 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               139367 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'MCHR1-Gi complex S3 state' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3, 4, 5' 
# 
_em_imaging.entry_id                        8WWI 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1200 
_em_imaging.nominal_defocus_max             2200 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8WWI 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8WWI 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1   ? A MET 1   
2   1 Y 1 A GLY 2   ? A GLY 2   
3   1 Y 1 A CYS 3   ? A CYS 3   
4   1 Y 1 A ILE 55  ? A ILE 55  
5   1 Y 1 A ILE 56  ? A ILE 56  
6   1 Y 1 A HIS 57  ? A HIS 57  
7   1 Y 1 A GLU 58  ? A GLU 58  
8   1 Y 1 A ALA 59  ? A ALA 59  
9   1 Y 1 A GLY 60  ? A GLY 60  
10  1 Y 1 A TYR 61  ? A TYR 61  
11  1 Y 1 A SER 62  ? A SER 62  
12  1 Y 1 A GLU 63  ? A GLU 63  
13  1 Y 1 A GLU 64  ? A GLU 64  
14  1 Y 1 A GLU 65  ? A GLU 65  
15  1 Y 1 A CYS 66  ? A CYS 66  
16  1 Y 1 A LYS 67  ? A LYS 67  
17  1 Y 1 A GLN 68  ? A GLN 68  
18  1 Y 1 A TYR 69  ? A TYR 69  
19  1 Y 1 A LYS 70  ? A LYS 70  
20  1 Y 1 A ALA 71  ? A ALA 71  
21  1 Y 1 A VAL 72  ? A VAL 72  
22  1 Y 1 A VAL 73  ? A VAL 73  
23  1 Y 1 A TYR 74  ? A TYR 74  
24  1 Y 1 A SER 75  ? A SER 75  
25  1 Y 1 A ASN 76  ? A ASN 76  
26  1 Y 1 A THR 77  ? A THR 77  
27  1 Y 1 A ILE 78  ? A ILE 78  
28  1 Y 1 A GLN 79  ? A GLN 79  
29  1 Y 1 A SER 80  ? A SER 80  
30  1 Y 1 A ILE 81  ? A ILE 81  
31  1 Y 1 A ILE 82  ? A ILE 82  
32  1 Y 1 A ALA 83  ? A ALA 83  
33  1 Y 1 A ILE 84  ? A ILE 84  
34  1 Y 1 A ILE 85  ? A ILE 85  
35  1 Y 1 A ARG 86  ? A ARG 86  
36  1 Y 1 A ALA 87  ? A ALA 87  
37  1 Y 1 A MET 88  ? A MET 88  
38  1 Y 1 A GLY 89  ? A GLY 89  
39  1 Y 1 A ARG 90  ? A ARG 90  
40  1 Y 1 A LEU 91  ? A LEU 91  
41  1 Y 1 A LYS 92  ? A LYS 92  
42  1 Y 1 A ILE 93  ? A ILE 93  
43  1 Y 1 A ASP 94  ? A ASP 94  
44  1 Y 1 A PHE 95  ? A PHE 95  
45  1 Y 1 A GLY 96  ? A GLY 96  
46  1 Y 1 A ASP 97  ? A ASP 97  
47  1 Y 1 A SER 98  ? A SER 98  
48  1 Y 1 A ALA 99  ? A ALA 99  
49  1 Y 1 A ARG 100 ? A ARG 100 
50  1 Y 1 A ALA 101 ? A ALA 101 
51  1 Y 1 A ASP 102 ? A ASP 102 
52  1 Y 1 A ASP 103 ? A ASP 103 
53  1 Y 1 A ALA 104 ? A ALA 104 
54  1 Y 1 A ARG 105 ? A ARG 105 
55  1 Y 1 A GLN 106 ? A GLN 106 
56  1 Y 1 A LEU 107 ? A LEU 107 
57  1 Y 1 A PHE 108 ? A PHE 108 
58  1 Y 1 A VAL 109 ? A VAL 109 
59  1 Y 1 A LEU 110 ? A LEU 110 
60  1 Y 1 A ALA 111 ? A ALA 111 
61  1 Y 1 A GLY 112 ? A GLY 112 
62  1 Y 1 A ALA 113 ? A ALA 113 
63  1 Y 1 A ALA 114 ? A ALA 114 
64  1 Y 1 A GLU 115 ? A GLU 115 
65  1 Y 1 A GLU 116 ? A GLU 116 
66  1 Y 1 A GLY 117 ? A GLY 117 
67  1 Y 1 A PHE 118 ? A PHE 118 
68  1 Y 1 A MET 119 ? A MET 119 
69  1 Y 1 A THR 120 ? A THR 120 
70  1 Y 1 A ALA 121 ? A ALA 121 
71  1 Y 1 A GLU 122 ? A GLU 122 
72  1 Y 1 A LEU 123 ? A LEU 123 
73  1 Y 1 A ALA 124 ? A ALA 124 
74  1 Y 1 A GLY 125 ? A GLY 125 
75  1 Y 1 A VAL 126 ? A VAL 126 
76  1 Y 1 A ILE 127 ? A ILE 127 
77  1 Y 1 A LYS 128 ? A LYS 128 
78  1 Y 1 A ARG 129 ? A ARG 129 
79  1 Y 1 A LEU 130 ? A LEU 130 
80  1 Y 1 A TRP 131 ? A TRP 131 
81  1 Y 1 A LYS 132 ? A LYS 132 
82  1 Y 1 A ASP 133 ? A ASP 133 
83  1 Y 1 A SER 134 ? A SER 134 
84  1 Y 1 A GLY 135 ? A GLY 135 
85  1 Y 1 A VAL 136 ? A VAL 136 
86  1 Y 1 A GLN 137 ? A GLN 137 
87  1 Y 1 A ALA 138 ? A ALA 138 
88  1 Y 1 A CYS 139 ? A CYS 139 
89  1 Y 1 A PHE 140 ? A PHE 140 
90  1 Y 1 A ASN 141 ? A ASN 141 
91  1 Y 1 A ARG 142 ? A ARG 142 
92  1 Y 1 A SER 143 ? A SER 143 
93  1 Y 1 A ARG 144 ? A ARG 144 
94  1 Y 1 A GLU 145 ? A GLU 145 
95  1 Y 1 A TYR 146 ? A TYR 146 
96  1 Y 1 A GLN 147 ? A GLN 147 
97  1 Y 1 A LEU 148 ? A LEU 148 
98  1 Y 1 A ASN 149 ? A ASN 149 
99  1 Y 1 A ASP 150 ? A ASP 150 
100 1 Y 1 A SER 151 ? A SER 151 
101 1 Y 1 A ALA 152 ? A ALA 152 
102 1 Y 1 A ALA 153 ? A ALA 153 
103 1 Y 1 A TYR 154 ? A TYR 154 
104 1 Y 1 A TYR 155 ? A TYR 155 
105 1 Y 1 A LEU 156 ? A LEU 156 
106 1 Y 1 A ASN 157 ? A ASN 157 
107 1 Y 1 A ASP 158 ? A ASP 158 
108 1 Y 1 A LEU 159 ? A LEU 159 
109 1 Y 1 A ASP 160 ? A ASP 160 
110 1 Y 1 A ARG 161 ? A ARG 161 
111 1 Y 1 A ILE 162 ? A ILE 162 
112 1 Y 1 A ALA 163 ? A ALA 163 
113 1 Y 1 A GLN 164 ? A GLN 164 
114 1 Y 1 A PRO 165 ? A PRO 165 
115 1 Y 1 A ASN 166 ? A ASN 166 
116 1 Y 1 A TYR 167 ? A TYR 167 
117 1 Y 1 A ILE 168 ? A ILE 168 
118 1 Y 1 A PRO 169 ? A PRO 169 
119 1 Y 1 A THR 170 ? A THR 170 
120 1 Y 1 A GLN 171 ? A GLN 171 
121 1 Y 1 A GLN 172 ? A GLN 172 
122 1 Y 1 A ASP 173 ? A ASP 173 
123 1 Y 1 A VAL 174 ? A VAL 174 
124 1 Y 1 A LEU 175 ? A LEU 175 
125 1 Y 1 A ARG 176 ? A ARG 176 
126 1 Y 1 A THR 177 ? A THR 177 
127 1 Y 1 A ARG 178 ? A ARG 178 
128 1 Y 1 A VAL 179 ? A VAL 179 
129 1 Y 1 A LYS 180 ? A LYS 180 
130 1 Y 1 A THR 181 ? A THR 181 
131 1 Y 1 B MET -9  ? B MET 1   
132 1 Y 1 B HIS -8  ? B HIS 2   
133 1 Y 1 B HIS -7  ? B HIS 3   
134 1 Y 1 B HIS -6  ? B HIS 4   
135 1 Y 1 B HIS -5  ? B HIS 5   
136 1 Y 1 B HIS -4  ? B HIS 6   
137 1 Y 1 B HIS -3  ? B HIS 7   
138 1 Y 1 B GLY -2  ? B GLY 8   
139 1 Y 1 B SER -1  ? B SER 9   
140 1 Y 1 B SER 0   ? B SER 10  
141 1 Y 1 B GLY 1   ? B GLY 11  
142 1 Y 1 B GLY 344 ? B GLY 354 
143 1 Y 1 B GLY 345 ? B GLY 355 
144 1 Y 1 B GLY 346 ? B GLY 356 
145 1 Y 1 B GLY 347 ? B GLY 357 
146 1 Y 1 B SER 348 ? B SER 358 
147 1 Y 1 B GLY 349 ? B GLY 359 
148 1 Y 1 B GLY 350 ? B GLY 360 
149 1 Y 1 B GLY 351 ? B GLY 361 
150 1 Y 1 B GLY 352 ? B GLY 362 
151 1 Y 1 B SER 353 ? B SER 363 
152 1 Y 1 B SER 354 ? B SER 364 
153 1 Y 1 B GLY 355 ? B GLY 365 
154 1 Y 1 B VAL 356 ? B VAL 366 
155 1 Y 1 B SER 357 ? B SER 367 
156 1 Y 1 B GLY 358 ? B GLY 368 
157 1 Y 1 B TRP 359 ? B TRP 369 
158 1 Y 1 B ARG 360 ? B ARG 370 
159 1 Y 1 B LEU 361 ? B LEU 371 
160 1 Y 1 B PHE 362 ? B PHE 372 
161 1 Y 1 B LYS 363 ? B LYS 373 
162 1 Y 1 B LYS 364 ? B LYS 374 
163 1 Y 1 B ILE 365 ? B ILE 375 
164 1 Y 1 B SER 366 ? B SER 376 
165 1 Y 1 C MET 1   ? C MET 1   
166 1 Y 1 C ALA 2   ? C ALA 2   
167 1 Y 1 C SER 3   ? C SER 3   
168 1 Y 1 C ASN 4   ? C ASN 4   
169 1 Y 1 C ASN 5   ? C ASN 5   
170 1 Y 1 C GLU 63  ? C GLU 63  
171 1 Y 1 C LYS 64  ? C LYS 64  
172 1 Y 1 C LYS 65  ? C LYS 65  
173 1 Y 1 C PHE 66  ? C PHE 66  
174 1 Y 1 C PHE 67  ? C PHE 67  
175 1 Y 1 C CYS 68  ? C CYS 68  
176 1 Y 1 C ALA 69  ? C ALA 69  
177 1 Y 1 C ILE 70  ? C ILE 70  
178 1 Y 1 C LEU 71  ? C LEU 71  
179 1 Y 1 E SER 121 ? D SER 121 
180 1 Y 1 E GLY 122 ? D GLY 122 
181 1 Y 1 E GLY 123 ? D GLY 123 
182 1 Y 1 E GLY 124 ? D GLY 124 
183 1 Y 1 E GLY 125 ? D GLY 125 
184 1 Y 1 E SER 126 ? D SER 126 
185 1 Y 1 E GLY 127 ? D GLY 127 
186 1 Y 1 E GLY 128 ? D GLY 128 
187 1 Y 1 E GLY 129 ? D GLY 129 
188 1 Y 1 E GLY 130 ? D GLY 130 
189 1 Y 1 E SER 131 ? D SER 131 
190 1 Y 1 E GLY 132 ? D GLY 132 
191 1 Y 1 E GLY 133 ? D GLY 133 
192 1 Y 1 E GLY 134 ? D GLY 134 
193 1 Y 1 E GLY 135 ? D GLY 135 
194 1 Y 1 E SER 136 ? D SER 136 
195 1 Y 1 E LEU 248 ? D LEU 248 
196 1 Y 1 E GLU 249 ? D GLU 249 
197 1 Y 1 E GLU 250 ? D GLU 250 
198 1 Y 1 E ASN 251 ? D ASN 251 
199 1 Y 1 E LEU 252 ? D LEU 252 
200 1 Y 1 E TYR 253 ? D TYR 253 
201 1 Y 1 E PHE 254 ? D PHE 254 
202 1 Y 1 E GLN 255 ? D GLN 255 
203 1 Y 1 R ASP -52 ? E ASP 1   
204 1 Y 1 R TYR -51 ? E TYR 2   
205 1 Y 1 R LYS -50 ? E LYS 3   
206 1 Y 1 R ASP -49 ? E ASP 4   
207 1 Y 1 R ASP -48 ? E ASP 5   
208 1 Y 1 R ASP -47 ? E ASP 6   
209 1 Y 1 R ASP -46 ? E ASP 7   
210 1 Y 1 R HIS -45 ? E HIS 8   
211 1 Y 1 R HIS -44 ? E HIS 9   
212 1 Y 1 R HIS -43 ? E HIS 10  
213 1 Y 1 R HIS -42 ? E HIS 11  
214 1 Y 1 R HIS -41 ? E HIS 12  
215 1 Y 1 R HIS -40 ? E HIS 13  
216 1 Y 1 R HIS -39 ? E HIS 14  
217 1 Y 1 R HIS -38 ? E HIS 15  
218 1 Y 1 R GLY -37 ? E GLY 16  
219 1 Y 1 R GLN -36 ? E GLN 17  
220 1 Y 1 R PRO -35 ? E PRO 18  
221 1 Y 1 R GLY -34 ? E GLY 19  
222 1 Y 1 R ASN -33 ? E ASN 20  
223 1 Y 1 R GLY -32 ? E GLY 21  
224 1 Y 1 R SER -31 ? E SER 22  
225 1 Y 1 R ALA -30 ? E ALA 23  
226 1 Y 1 R PHE -29 ? E PHE 24  
227 1 Y 1 R LEU -28 ? E LEU 25  
228 1 Y 1 R LEU -27 ? E LEU 26  
229 1 Y 1 R ALA -26 ? E ALA 27  
230 1 Y 1 R PRO -25 ? E PRO 28  
231 1 Y 1 R ASN -24 ? E ASN 29  
232 1 Y 1 R GLY -23 ? E GLY 30  
233 1 Y 1 R SER -22 ? E SER 31  
234 1 Y 1 R HIS -21 ? E HIS 32  
235 1 Y 1 R ALA -20 ? E ALA 33  
236 1 Y 1 R PRO -19 ? E PRO 34  
237 1 Y 1 R ASP -18 ? E ASP 35  
238 1 Y 1 R HIS -17 ? E HIS 36  
239 1 Y 1 R ASN -16 ? E ASN 37  
240 1 Y 1 R VAL -15 ? E VAL 38  
241 1 Y 1 R THR -14 ? E THR 39  
242 1 Y 1 R GLN -13 ? E GLN 40  
243 1 Y 1 R GLN -12 ? E GLN 41  
244 1 Y 1 R ARG -11 ? E ARG 42  
245 1 Y 1 R ASP -10 ? E ASP 43  
246 1 Y 1 R GLU -9  ? E GLU 44  
247 1 Y 1 R GLU -8  ? E GLU 45  
248 1 Y 1 R ASN -7  ? E ASN 46  
249 1 Y 1 R LEU -6  ? E LEU 47  
250 1 Y 1 R TYR -5  ? E TYR 48  
251 1 Y 1 R PHE -4  ? E PHE 49  
252 1 Y 1 R GLN -3  ? E GLN 50  
253 1 Y 1 R GLY -2  ? E GLY 51  
254 1 Y 1 R VAL -1  ? E VAL 52  
255 1 Y 1 R ASP 0   ? E ASP 53  
256 1 Y 1 R MET 1   ? E MET 54  
257 1 Y 1 R SER 2   ? E SER 55  
258 1 Y 1 R VAL 3   ? E VAL 56  
259 1 Y 1 R GLY 4   ? E GLY 57  
260 1 Y 1 R ALA 5   ? E ALA 58  
261 1 Y 1 R MET 6   ? E MET 59  
262 1 Y 1 R LYS 7   ? E LYS 60  
263 1 Y 1 R LYS 8   ? E LYS 61  
264 1 Y 1 R GLY 9   ? E GLY 62  
265 1 Y 1 R VAL 10  ? E VAL 63  
266 1 Y 1 R GLY 11  ? E GLY 64  
267 1 Y 1 R ARG 12  ? E ARG 65  
268 1 Y 1 R ALA 13  ? E ALA 66  
269 1 Y 1 R VAL 14  ? E VAL 67  
270 1 Y 1 R GLY 15  ? E GLY 68  
271 1 Y 1 R LEU 16  ? E LEU 69  
272 1 Y 1 R GLY 17  ? E GLY 70  
273 1 Y 1 R GLY 18  ? E GLY 71  
274 1 Y 1 R GLY 19  ? E GLY 72  
275 1 Y 1 R SER 20  ? E SER 73  
276 1 Y 1 R GLY 21  ? E GLY 74  
277 1 Y 1 R CYS 22  ? E CYS 75  
278 1 Y 1 R GLN 23  ? E GLN 76  
279 1 Y 1 R ALA 24  ? E ALA 77  
280 1 Y 1 R THR 25  ? E THR 78  
281 1 Y 1 R GLU 26  ? E GLU 79  
282 1 Y 1 R GLU 27  ? E GLU 80  
283 1 Y 1 R ASP 28  ? E ASP 81  
284 1 Y 1 R PRO 29  ? E PRO 82  
285 1 Y 1 R LEU 30  ? E LEU 83  
286 1 Y 1 R PRO 31  ? E PRO 84  
287 1 Y 1 R ASN 32  ? E ASN 85  
288 1 Y 1 R CYS 33  ? E CYS 86  
289 1 Y 1 R GLY 34  ? E GLY 87  
290 1 Y 1 R ALA 35  ? E ALA 88  
291 1 Y 1 R CYS 36  ? E CYS 89  
292 1 Y 1 R ALA 37  ? E ALA 90  
293 1 Y 1 R PRO 38  ? E PRO 91  
294 1 Y 1 R GLY 39  ? E GLY 92  
295 1 Y 1 R GLN 40  ? E GLN 93  
296 1 Y 1 R GLY 41  ? E GLY 94  
297 1 Y 1 R GLY 42  ? E GLY 95  
298 1 Y 1 R ARG 43  ? E ARG 96  
299 1 Y 1 R ARG 44  ? E ARG 97  
300 1 Y 1 R TRP 45  ? E TRP 98  
301 1 Y 1 R ARG 46  ? E ARG 99  
302 1 Y 1 R LEU 47  ? E LEU 100 
303 1 Y 1 R PRO 48  ? E PRO 101 
304 1 Y 1 R GLN 49  ? E GLN 102 
305 1 Y 1 R PRO 50  ? E PRO 103 
306 1 Y 1 R ALA 51  ? E ALA 104 
307 1 Y 1 R TRP 52  ? E TRP 105 
308 1 Y 1 R VAL 53  ? E VAL 106 
309 1 Y 1 R GLU 54  ? E GLU 107 
310 1 Y 1 R GLY 55  ? E GLY 108 
311 1 Y 1 R SER 56  ? E SER 109 
312 1 Y 1 R SER 57  ? E SER 110 
313 1 Y 1 R ALA 58  ? E ALA 111 
314 1 Y 1 R ARG 59  ? E ARG 112 
315 1 Y 1 R LEU 60  ? E LEU 113 
316 1 Y 1 R TRP 61  ? E TRP 114 
317 1 Y 1 R GLU 62  ? E GLU 115 
318 1 Y 1 R GLN 63  ? E GLN 116 
319 1 Y 1 R ALA 64  ? E ALA 117 
320 1 Y 1 R THR 65  ? E THR 118 
321 1 Y 1 R GLY 66  ? E GLY 119 
322 1 Y 1 R THR 67  ? E THR 120 
323 1 Y 1 R GLY 68  ? E GLY 121 
324 1 Y 1 R TRP 69  ? E TRP 122 
325 1 Y 1 R MET 70  ? E MET 123 
326 1 Y 1 R ASP 71  ? E ASP 124 
327 1 Y 1 R LEU 72  ? E LEU 125 
328 1 Y 1 R GLU 73  ? E GLU 126 
329 1 Y 1 R ALA 74  ? E ALA 127 
330 1 Y 1 R SER 75  ? E SER 128 
331 1 Y 1 R LEU 76  ? E LEU 129 
332 1 Y 1 R LEU 77  ? E LEU 130 
333 1 Y 1 R PRO 78  ? E PRO 131 
334 1 Y 1 R THR 79  ? E THR 132 
335 1 Y 1 R GLY 80  ? E GLY 133 
336 1 Y 1 R PRO 81  ? E PRO 134 
337 1 Y 1 R ASN 82  ? E ASN 135 
338 1 Y 1 R ALA 83  ? E ALA 136 
339 1 Y 1 R SER 84  ? E SER 137 
340 1 Y 1 R ASN 85  ? E ASN 138 
341 1 Y 1 R THR 86  ? E THR 139 
342 1 Y 1 R SER 87  ? E SER 140 
343 1 Y 1 R ASP 88  ? E ASP 141 
344 1 Y 1 R GLY 89  ? E GLY 142 
345 1 Y 1 R PRO 90  ? E PRO 143 
346 1 Y 1 R ASP 91  ? E ASP 144 
347 1 Y 1 R ASN 92  ? E ASN 145 
348 1 Y 1 R LEU 93  ? E LEU 146 
349 1 Y 1 R THR 94  ? E THR 147 
350 1 Y 1 R SER 95  ? E SER 148 
351 1 Y 1 R ALA 96  ? E ALA 149 
352 1 Y 1 R GLY 97  ? E GLY 150 
353 1 Y 1 R SER 98  ? E SER 151 
354 1 Y 1 R PRO 99  ? E PRO 152 
355 1 Y 1 R PRO 100 ? E PRO 153 
356 1 Y 1 R ARG 101 ? E ARG 154 
357 1 Y 1 R THR 102 ? E THR 155 
358 1 Y 1 R GLY 103 ? E GLY 156 
359 1 Y 1 R SER 104 ? E SER 157 
360 1 Y 1 R ILE 105 ? E ILE 158 
361 1 Y 1 R SER 106 ? E SER 159 
362 1 Y 1 R LYS 396 ? E LYS 449 
363 1 Y 1 R HIS 397 ? E HIS 450 
364 1 Y 1 R MET 398 ? E MET 451 
365 1 Y 1 R GLY 399 ? E GLY 452 
366 1 Y 1 R SER 400 ? E SER 453 
367 1 Y 1 R SER 401 ? E SER 454 
368 1 Y 1 R GLY 402 ? E GLY 455 
369 1 Y 1 R GLY 403 ? E GLY 456 
370 1 Y 1 R GLY 404 ? E GLY 457 
371 1 Y 1 R GLY 405 ? E GLY 458 
372 1 Y 1 R SER 406 ? E SER 459 
373 1 Y 1 R GLY 407 ? E GLY 460 
374 1 Y 1 R GLY 408 ? E GLY 461 
375 1 Y 1 R GLY 409 ? E GLY 462 
376 1 Y 1 R GLY 410 ? E GLY 463 
377 1 Y 1 R SER 411 ? E SER 464 
378 1 Y 1 R SER 412 ? E SER 465 
379 1 Y 1 R GLY 413 ? E GLY 466 
380 1 Y 1 R VAL 414 ? E VAL 467 
381 1 Y 1 R PHE 415 ? E PHE 468 
382 1 Y 1 R THR 416 ? E THR 469 
383 1 Y 1 R LEU 417 ? E LEU 470 
384 1 Y 1 R GLU 418 ? E GLU 471 
385 1 Y 1 R ASP 419 ? E ASP 472 
386 1 Y 1 R PHE 420 ? E PHE 473 
387 1 Y 1 R VAL 421 ? E VAL 474 
388 1 Y 1 R GLY 422 ? E GLY 475 
389 1 Y 1 R ASP 423 ? E ASP 476 
390 1 Y 1 R TRP 424 ? E TRP 477 
391 1 Y 1 R GLU 425 ? E GLU 478 
392 1 Y 1 R GLN 426 ? E GLN 479 
393 1 Y 1 R THR 427 ? E THR 480 
394 1 Y 1 R ALA 428 ? E ALA 481 
395 1 Y 1 R ALA 429 ? E ALA 482 
396 1 Y 1 R TYR 430 ? E TYR 483 
397 1 Y 1 R ASN 431 ? E ASN 484 
398 1 Y 1 R LEU 432 ? E LEU 485 
399 1 Y 1 R ASP 433 ? E ASP 486 
400 1 Y 1 R GLN 434 ? E GLN 487 
401 1 Y 1 R VAL 435 ? E VAL 488 
402 1 Y 1 R LEU 436 ? E LEU 489 
403 1 Y 1 R GLU 437 ? E GLU 490 
404 1 Y 1 R GLN 438 ? E GLN 491 
405 1 Y 1 R GLY 439 ? E GLY 492 
406 1 Y 1 R GLY 440 ? E GLY 493 
407 1 Y 1 R VAL 441 ? E VAL 494 
408 1 Y 1 R SER 442 ? E SER 495 
409 1 Y 1 R SER 443 ? E SER 496 
410 1 Y 1 R LEU 444 ? E LEU 497 
411 1 Y 1 R LEU 445 ? E LEU 498 
412 1 Y 1 R GLN 446 ? E GLN 499 
413 1 Y 1 R ASN 447 ? E ASN 500 
414 1 Y 1 R LEU 448 ? E LEU 501 
415 1 Y 1 R ALA 449 ? E ALA 502 
416 1 Y 1 R VAL 450 ? E VAL 503 
417 1 Y 1 R SER 451 ? E SER 504 
418 1 Y 1 R VAL 452 ? E VAL 505 
419 1 Y 1 R THR 453 ? E THR 506 
420 1 Y 1 R PRO 454 ? E PRO 507 
421 1 Y 1 R ILE 455 ? E ILE 508 
422 1 Y 1 R GLN 456 ? E GLN 509 
423 1 Y 1 R ARG 457 ? E ARG 510 
424 1 Y 1 R ILE 458 ? E ILE 511 
425 1 Y 1 R VAL 459 ? E VAL 512 
426 1 Y 1 R ARG 460 ? E ARG 513 
427 1 Y 1 R SER 461 ? E SER 514 
428 1 Y 1 R GLY 462 ? E GLY 515 
429 1 Y 1 R GLU 463 ? E GLU 516 
430 1 Y 1 R ASN 464 ? E ASN 517 
431 1 Y 1 R ALA 465 ? E ALA 518 
432 1 Y 1 R LEU 466 ? E LEU 519 
433 1 Y 1 R LYS 467 ? E LYS 520 
434 1 Y 1 R ILE 468 ? E ILE 521 
435 1 Y 1 R ASP 469 ? E ASP 522 
436 1 Y 1 R ILE 470 ? E ILE 523 
437 1 Y 1 R HIS 471 ? E HIS 524 
438 1 Y 1 R VAL 472 ? E VAL 525 
439 1 Y 1 R ILE 473 ? E ILE 526 
440 1 Y 1 R ILE 474 ? E ILE 527 
441 1 Y 1 R PRO 475 ? E PRO 528 
442 1 Y 1 R TYR 476 ? E TYR 529 
443 1 Y 1 R GLU 477 ? E GLU 530 
444 1 Y 1 R GLY 478 ? E GLY 531 
445 1 Y 1 R LEU 479 ? E LEU 532 
446 1 Y 1 R SER 480 ? E SER 533 
447 1 Y 1 R ALA 481 ? E ALA 534 
448 1 Y 1 R ASP 482 ? E ASP 535 
449 1 Y 1 R GLN 483 ? E GLN 536 
450 1 Y 1 R MET 484 ? E MET 537 
451 1 Y 1 R ALA 485 ? E ALA 538 
452 1 Y 1 R GLN 486 ? E GLN 539 
453 1 Y 1 R ILE 487 ? E ILE 540 
454 1 Y 1 R GLU 488 ? E GLU 541 
455 1 Y 1 R GLU 489 ? E GLU 542 
456 1 Y 1 R VAL 490 ? E VAL 543 
457 1 Y 1 R PHE 491 ? E PHE 544 
458 1 Y 1 R LYS 492 ? E LYS 545 
459 1 Y 1 R VAL 493 ? E VAL 546 
460 1 Y 1 R VAL 494 ? E VAL 547 
461 1 Y 1 R TYR 495 ? E TYR 548 
462 1 Y 1 R PRO 496 ? E PRO 549 
463 1 Y 1 R VAL 497 ? E VAL 550 
464 1 Y 1 R ASP 498 ? E ASP 551 
465 1 Y 1 R ASP 499 ? E ASP 552 
466 1 Y 1 R HIS 500 ? E HIS 553 
467 1 Y 1 R HIS 501 ? E HIS 554 
468 1 Y 1 R PHE 502 ? E PHE 555 
469 1 Y 1 R LYS 503 ? E LYS 556 
470 1 Y 1 R VAL 504 ? E VAL 557 
471 1 Y 1 R ILE 505 ? E ILE 558 
472 1 Y 1 R LEU 506 ? E LEU 559 
473 1 Y 1 R PRO 507 ? E PRO 560 
474 1 Y 1 R TYR 508 ? E TYR 561 
475 1 Y 1 R GLY 509 ? E GLY 562 
476 1 Y 1 R THR 510 ? E THR 563 
477 1 Y 1 R LEU 511 ? E LEU 564 
478 1 Y 1 R VAL 512 ? E VAL 565 
479 1 Y 1 R ILE 513 ? E ILE 566 
480 1 Y 1 R ASP 514 ? E ASP 567 
481 1 Y 1 R GLY 515 ? E GLY 568 
482 1 Y 1 R VAL 516 ? E VAL 569 
483 1 Y 1 R THR 517 ? E THR 570 
484 1 Y 1 R PRO 518 ? E PRO 571 
485 1 Y 1 R ASN 519 ? E ASN 572 
486 1 Y 1 R MET 520 ? E MET 573 
487 1 Y 1 R LEU 521 ? E LEU 574 
488 1 Y 1 R ASN 522 ? E ASN 575 
489 1 Y 1 R TYR 523 ? E TYR 576 
490 1 Y 1 R PHE 524 ? E PHE 577 
491 1 Y 1 R GLY 525 ? E GLY 578 
492 1 Y 1 R ARG 526 ? E ARG 579 
493 1 Y 1 R PRO 527 ? E PRO 580 
494 1 Y 1 R TYR 528 ? E TYR 581 
495 1 Y 1 R GLU 529 ? E GLU 582 
496 1 Y 1 R GLY 530 ? E GLY 583 
497 1 Y 1 R ILE 531 ? E ILE 584 
498 1 Y 1 R ALA 532 ? E ALA 585 
499 1 Y 1 R VAL 533 ? E VAL 586 
500 1 Y 1 R PHE 534 ? E PHE 587 
501 1 Y 1 R ASP 535 ? E ASP 588 
502 1 Y 1 R GLY 536 ? E GLY 589 
503 1 Y 1 R LYS 537 ? E LYS 590 
504 1 Y 1 R LYS 538 ? E LYS 591 
505 1 Y 1 R ILE 539 ? E ILE 592 
506 1 Y 1 R THR 540 ? E THR 593 
507 1 Y 1 R VAL 541 ? E VAL 594 
508 1 Y 1 R THR 542 ? E THR 595 
509 1 Y 1 R GLY 543 ? E GLY 596 
510 1 Y 1 R THR 544 ? E THR 597 
511 1 Y 1 R LEU 545 ? E LEU 598 
512 1 Y 1 R TRP 546 ? E TRP 599 
513 1 Y 1 R ASN 547 ? E ASN 600 
514 1 Y 1 R GLY 548 ? E GLY 601 
515 1 Y 1 R ASN 549 ? E ASN 602 
516 1 Y 1 R LYS 550 ? E LYS 603 
517 1 Y 1 R ILE 551 ? E ILE 604 
518 1 Y 1 R ILE 552 ? E ILE 605 
519 1 Y 1 R ASP 553 ? E ASP 606 
520 1 Y 1 R GLU 554 ? E GLU 607 
521 1 Y 1 R ARG 555 ? E ARG 608 
522 1 Y 1 R LEU 556 ? E LEU 609 
523 1 Y 1 R ILE 557 ? E ILE 610 
524 1 Y 1 R THR 558 ? E THR 611 
525 1 Y 1 R PRO 559 ? E PRO 612 
526 1 Y 1 R ASP 560 ? E ASP 613 
527 1 Y 1 R GLY 561 ? E GLY 614 
528 1 Y 1 R SER 562 ? E SER 615 
529 1 Y 1 R MET 563 ? E MET 616 
530 1 Y 1 R LEU 564 ? E LEU 617 
531 1 Y 1 R PHE 565 ? E PHE 618 
532 1 Y 1 R ARG 566 ? E ARG 619 
533 1 Y 1 R VAL 567 ? E VAL 620 
534 1 Y 1 R THR 568 ? E THR 621 
535 1 Y 1 R ILE 569 ? E ILE 622 
536 1 Y 1 R ASN 570 ? E ASN 623 
537 1 Y 1 R SER 571 ? E SER 624 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-10-25 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8WWI 
_em_admin.last_update        2024-11-27 
_em_admin.map_release_date   2024-11-13 
_em_admin.title              'MCHR1-Gi complex,S3 state' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          274590 
_em_entity_assembly_recombinant.organism             'Baculovirus expression vector pFastBac1-HM' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         55 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ?      ?            
'MODEL REFINEMENT'         ? 2  ? ? ? PHENIX 1.20.1_4487: 
'IMAGE ACQUISITION'        ? 3  ? ? 1 ?      ?            
MASKING                    ? 4  ? ? ? ?      ?            
'CTF CORRECTION'           ? 5  1 ? ? ?      ?            
'LAYERLINE INDEXING'       ? 6  ? ? ? ?      ?            
'DIFFRACTION INDEXING'     ? 7  ? ? ? ?      ?            
'MODEL FITTING'            ? 8  ? ? ? ?      ?            
OTHER                      ? 9  ? ? ? ?      ?            
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ?      ?            
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ?      ?            
CLASSIFICATION             ? 12 1 ? ? ?      ?            
RECONSTRUCTION             ? 13 1 ? ? ?      ?            
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           T2221005 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    8WWI 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . THR A 1 4   ? 92.597  79.398  93.068  1.00 97.87  ? 4   THR A N   1 
ATOM 2    C CA  . THR A 1 4   ? 92.104  78.784  91.841  1.00 100.27 ? 4   THR A CA  1 
ATOM 3    C C   . THR A 1 4   ? 92.809  79.360  90.618  1.00 100.77 ? 4   THR A C   1 
ATOM 4    O O   . THR A 1 4   ? 92.219  79.475  89.545  1.00 99.32  ? 4   THR A O   1 
ATOM 5    C CB  . THR A 1 4   ? 90.584  78.973  91.686  1.00 99.42  ? 4   THR A CB  1 
ATOM 6    O OG1 . THR A 1 4   ? 90.276  80.372  91.631  1.00 100.63 ? 4   THR A OG1 1 
ATOM 7    C CG2 . THR A 1 4   ? 89.847  78.340  92.856  1.00 97.02  ? 4   THR A CG2 1 
ATOM 8    N N   . LEU A 1 5   ? 94.078  79.717  90.791  1.00 82.04  ? 5   LEU A N   1 
ATOM 9    C CA  . LEU A 1 5   ? 94.899  80.237  89.707  1.00 76.30  ? 5   LEU A CA  1 
ATOM 10   C C   . LEU A 1 5   ? 95.645  79.098  89.024  1.00 75.99  ? 5   LEU A C   1 
ATOM 11   O O   . LEU A 1 5   ? 96.097  78.155  89.679  1.00 75.93  ? 5   LEU A O   1 
ATOM 12   C CB  . LEU A 1 5   ? 95.887  81.281  90.229  1.00 74.12  ? 5   LEU A CB  1 
ATOM 13   C CG  . LEU A 1 5   ? 95.273  82.513  90.898  1.00 74.82  ? 5   LEU A CG  1 
ATOM 14   C CD1 . LEU A 1 5   ? 96.357  83.451  91.409  1.00 75.68  ? 5   LEU A CD1 1 
ATOM 15   C CD2 . LEU A 1 5   ? 94.347  83.235  89.933  1.00 78.83  ? 5   LEU A CD2 1 
ATOM 16   N N   . SER A 1 6   ? 95.770  79.192  87.702  1.00 65.74  ? 6   SER A N   1 
ATOM 17   C CA  . SER A 1 6   ? 96.527  78.199  86.957  1.00 64.28  ? 6   SER A CA  1 
ATOM 18   C C   . SER A 1 6   ? 98.026  78.358  87.206  1.00 66.57  ? 6   SER A C   1 
ATOM 19   O O   . SER A 1 6   ? 98.492  79.324  87.817  1.00 68.86  ? 6   SER A O   1 
ATOM 20   C CB  . SER A 1 6   ? 96.223  78.307  85.463  1.00 65.75  ? 6   SER A CB  1 
ATOM 21   O OG  . SER A 1 6   ? 96.573  79.585  84.962  1.00 74.37  ? 6   SER A OG  1 
ATOM 22   N N   . ALA A 1 7   ? 98.786  77.371  86.721  1.00 60.75  ? 7   ALA A N   1 
ATOM 23   C CA  . ALA A 1 7   ? 100.231 77.360  86.931  1.00 60.03  ? 7   ALA A CA  1 
ATOM 24   C C   . ALA A 1 7   ? 100.915 78.568  86.303  1.00 62.41  ? 7   ALA A C   1 
ATOM 25   O O   . ALA A 1 7   ? 101.954 79.017  86.800  1.00 68.77  ? 7   ALA A O   1 
ATOM 26   C CB  . ALA A 1 7   ? 100.828 76.067  86.379  1.00 63.58  ? 7   ALA A CB  1 
ATOM 27   N N   . GLU A 1 8   ? 100.358 79.106  85.219  1.00 67.01  ? 8   GLU A N   1 
ATOM 28   C CA  . GLU A 1 8   ? 100.936 80.285  84.585  1.00 68.28  ? 8   GLU A CA  1 
ATOM 29   C C   . GLU A 1 8   ? 100.429 81.590  85.184  1.00 66.66  ? 8   GLU A C   1 
ATOM 30   O O   . GLU A 1 8   ? 101.165 82.583  85.191  1.00 72.30  ? 8   GLU A O   1 
ATOM 31   C CB  . GLU A 1 8   ? 100.656 80.268  83.079  1.00 70.79  ? 8   GLU A CB  1 
ATOM 32   C CG  . GLU A 1 8   ? 101.359 79.144  82.332  1.00 70.97  ? 8   GLU A CG  1 
ATOM 33   C CD  . GLU A 1 8   ? 101.260 79.294  80.826  1.00 74.12  ? 8   GLU A CD  1 
ATOM 34   O OE1 . GLU A 1 8   ? 100.728 80.325  80.363  1.00 78.78  ? 8   GLU A OE1 1 
ATOM 35   O OE2 . GLU A 1 8   ? 101.709 78.379  80.104  1.00 77.40  ? 8   GLU A OE2 1 
ATOM 36   N N   . ASP A 1 9   ? 99.190  81.613  85.682  1.00 59.07  ? 9   ASP A N   1 
ATOM 37   C CA  . ASP A 1 9   ? 98.703  82.795  86.386  1.00 59.30  ? 9   ASP A CA  1 
ATOM 38   C C   . ASP A 1 9   ? 99.505  83.049  87.656  1.00 59.25  ? 9   ASP A C   1 
ATOM 39   O O   . ASP A 1 9   ? 99.819  84.200  87.982  1.00 56.27  ? 9   ASP A O   1 
ATOM 40   C CB  . ASP A 1 9   ? 97.218  82.635  86.712  1.00 58.00  ? 9   ASP A CB  1 
ATOM 41   C CG  . ASP A 1 9   ? 96.347  82.653  85.474  1.00 58.95  ? 9   ASP A CG  1 
ATOM 42   O OD1 . ASP A 1 9   ? 96.890  82.859  84.368  1.00 60.25  ? 9   ASP A OD1 1 
ATOM 43   O OD2 . ASP A 1 9   ? 95.120  82.461  85.603  1.00 61.35  ? 9   ASP A OD2 1 
ATOM 44   N N   . LYS A 1 10  ? 99.842  81.985  88.388  1.00 59.40  ? 10  LYS A N   1 
ATOM 45   C CA  . LYS A 1 10  ? 100.649 82.132  89.595  1.00 53.32  ? 10  LYS A CA  1 
ATOM 46   C C   . LYS A 1 10  ? 102.052 82.635  89.277  1.00 51.18  ? 10  LYS A C   1 
ATOM 47   O O   . LYS A 1 10  ? 102.638 83.377  90.073  1.00 52.60  ? 10  LYS A O   1 
ATOM 48   C CB  . LYS A 1 10  ? 100.711 80.805  90.350  1.00 48.51  ? 10  LYS A CB  1 
ATOM 49   C CG  . LYS A 1 10  ? 99.367  80.344  90.886  1.00 44.82  ? 10  LYS A CG  1 
ATOM 50   C CD  . LYS A 1 10  ? 99.484  79.015  91.610  1.00 49.04  ? 10  LYS A CD  1 
ATOM 51   C CE  . LYS A 1 10  ? 98.142  78.583  92.176  1.00 60.00  ? 10  LYS A CE  1 
ATOM 52   N NZ  . LYS A 1 10  ? 98.228  77.272  92.873  1.00 55.87  ? 10  LYS A NZ  1 
ATOM 53   N N   . ALA A 1 11  ? 102.605 82.241  88.129  1.00 45.82  ? 11  ALA A N   1 
ATOM 54   C CA  . ALA A 1 11  ? 103.924 82.726  87.739  1.00 47.24  ? 11  ALA A CA  1 
ATOM 55   C C   . ALA A 1 11  ? 103.888 84.200  87.362  1.00 48.44  ? 11  ALA A C   1 
ATOM 56   O O   . ALA A 1 11  ? 104.865 84.923  87.592  1.00 54.81  ? 11  ALA A O   1 
ATOM 57   C CB  . ALA A 1 11  ? 104.469 81.893  86.580  1.00 44.81  ? 11  ALA A CB  1 
ATOM 58   N N   . ALA A 1 12  ? 102.782 84.659  86.774  1.00 37.17  ? 12  ALA A N   1 
ATOM 59   C CA  . ALA A 1 12  ? 102.628 86.079  86.481  1.00 35.43  ? 12  ALA A CA  1 
ATOM 60   C C   . ALA A 1 12  ? 102.587 86.906  87.760  1.00 44.84  ? 12  ALA A C   1 
ATOM 61   O O   . ALA A 1 12  ? 103.157 88.003  87.818  1.00 50.20  ? 12  ALA A O   1 
ATOM 62   C CB  . ALA A 1 12  ? 101.367 86.309  85.648  1.00 39.85  ? 12  ALA A CB  1 
ATOM 63   N N   . VAL A 1 13  ? 101.906 86.401  88.792  1.00 51.45  ? 13  VAL A N   1 
ATOM 64   C CA  . VAL A 1 13  ? 101.830 87.108  90.069  1.00 45.16  ? 13  VAL A CA  1 
ATOM 65   C C   . VAL A 1 13  ? 103.219 87.268  90.677  1.00 39.48  ? 13  VAL A C   1 
ATOM 66   O O   . VAL A 1 13  ? 103.564 88.333  91.203  1.00 50.21  ? 13  VAL A O   1 
ATOM 67   C CB  . VAL A 1 13  ? 100.872 86.376  91.028  1.00 47.49  ? 13  VAL A CB  1 
ATOM 68   C CG1 . VAL A 1 13  ? 100.915 87.006  92.414  1.00 46.21  ? 13  VAL A CG1 1 
ATOM 69   C CG2 . VAL A 1 13  ? 99.455  86.390  90.476  1.00 48.27  ? 13  VAL A CG2 1 
ATOM 70   N N   . GLU A 1 14  ? 104.038 86.215  90.611  1.00 41.06  ? 14  GLU A N   1 
ATOM 71   C CA  . GLU A 1 14  ? 105.398 86.300  91.134  1.00 44.76  ? 14  GLU A CA  1 
ATOM 72   C C   . GLU A 1 14  ? 106.237 87.315  90.367  1.00 52.50  ? 14  GLU A C   1 
ATOM 73   O O   . GLU A 1 14  ? 107.109 87.967  90.954  1.00 58.71  ? 14  GLU A O   1 
ATOM 74   C CB  . GLU A 1 14  ? 106.062 84.924  91.090  1.00 53.21  ? 14  GLU A CB  1 
ATOM 75   C CG  . GLU A 1 14  ? 107.438 84.875  91.735  1.00 57.85  ? 14  GLU A CG  1 
ATOM 76   C CD  . GLU A 1 14  ? 108.021 83.475  91.774  1.00 62.39  ? 14  GLU A CD  1 
ATOM 77   O OE1 . GLU A 1 14  ? 107.316 82.520  91.381  1.00 60.11  ? 14  GLU A OE1 1 
ATOM 78   O OE2 . GLU A 1 14  ? 109.187 83.329  92.197  1.00 63.33  ? 14  GLU A OE2 1 
ATOM 79   N N   . ARG A 1 15  ? 105.994 87.465  89.063  1.00 44.31  ? 15  ARG A N   1 
ATOM 80   C CA  . ARG A 1 15  ? 106.674 88.510  88.302  1.00 41.80  ? 15  ARG A CA  1 
ATOM 81   C C   . ARG A 1 15  ? 106.289 89.899  88.796  1.00 46.86  ? 15  ARG A C   1 
ATOM 82   O O   . ARG A 1 15  ? 107.144 90.786  88.906  1.00 52.79  ? 15  ARG A O   1 
ATOM 83   C CB  . ARG A 1 15  ? 106.359 88.368  86.812  1.00 39.03  ? 15  ARG A CB  1 
ATOM 84   C CG  . ARG A 1 15  ? 106.940 89.482  85.950  1.00 34.24  ? 15  ARG A CG  1 
ATOM 85   C CD  . ARG A 1 15  ? 106.787 89.181  84.467  1.00 42.04  ? 15  ARG A CD  1 
ATOM 86   N NE  . ARG A 1 15  ? 107.291 90.266  83.633  1.00 46.16  ? 15  ARG A NE  1 
ATOM 87   C CZ  . ARG A 1 15  ? 108.567 90.438  83.316  1.00 45.84  ? 15  ARG A CZ  1 
ATOM 88   N NH1 . ARG A 1 15  ? 109.504 89.613  83.752  1.00 43.58  ? 15  ARG A NH1 1 
ATOM 89   N NH2 . ARG A 1 15  ? 108.911 91.463  82.542  1.00 43.08  ? 15  ARG A NH2 1 
ATOM 90   N N   . SER A 1 16  ? 105.003 90.111  89.090  1.00 49.41  ? 16  SER A N   1 
ATOM 91   C CA  . SER A 1 16  ? 104.558 91.422  89.552  1.00 48.54  ? 16  SER A CA  1 
ATOM 92   C C   . SER A 1 16  ? 105.216 91.799  90.873  1.00 46.54  ? 16  SER A C   1 
ATOM 93   O O   . SER A 1 16  ? 105.629 92.949  91.065  1.00 55.08  ? 16  SER A O   1 
ATOM 94   C CB  . SER A 1 16  ? 103.036 91.440  89.687  1.00 42.89  ? 16  SER A CB  1 
ATOM 95   O OG  . SER A 1 16  ? 102.579 92.701  90.147  1.00 50.39  ? 16  SER A OG  1 
ATOM 96   N N   . LYS A 1 17  ? 105.320 90.845  91.800  1.00 41.48  ? 17  LYS A N   1 
ATOM 97   C CA  . LYS A 1 17  ? 105.998 91.100  93.065  1.00 46.94  ? 17  LYS A CA  1 
ATOM 98   C C   . LYS A 1 17  ? 107.494 91.340  92.902  1.00 44.41  ? 17  LYS A C   1 
ATOM 99   O O   . LYS A 1 17  ? 108.105 91.952  93.784  1.00 58.61  ? 17  LYS A O   1 
ATOM 100  C CB  . LYS A 1 17  ? 105.759 89.938  94.030  1.00 53.23  ? 17  LYS A CB  1 
ATOM 101  C CG  . LYS A 1 17  ? 104.306 89.772  94.432  1.00 52.55  ? 17  LYS A CG  1 
ATOM 102  C CD  . LYS A 1 17  ? 104.136 88.660  95.451  1.00 51.01  ? 17  LYS A CD  1 
ATOM 103  C CE  . LYS A 1 17  ? 102.687 88.536  95.888  1.00 47.57  ? 17  LYS A CE  1 
ATOM 104  N NZ  . LYS A 1 17  ? 102.518 87.474  96.915  1.00 55.90  ? 17  LYS A NZ  1 
ATOM 105  N N   . MET A 1 18  ? 108.102 90.873  91.809  1.00 41.97  ? 18  MET A N   1 
ATOM 106  C CA  . MET A 1 18  ? 109.493 91.231  91.551  1.00 56.33  ? 18  MET A CA  1 
ATOM 107  C C   . MET A 1 18  ? 109.620 92.672  91.073  1.00 61.36  ? 18  MET A C   1 
ATOM 108  O O   . MET A 1 18  ? 110.650 93.314  91.306  1.00 62.81  ? 18  MET A O   1 
ATOM 109  C CB  . MET A 1 18  ? 110.102 90.273  90.529  1.00 57.69  ? 18  MET A CB  1 
ATOM 110  C CG  . MET A 1 18  ? 110.386 88.883  91.074  1.00 67.58  ? 18  MET A CG  1 
ATOM 111  S SD  . MET A 1 18  ? 111.620 88.892  92.388  1.00 78.55  ? 18  MET A SD  1 
ATOM 112  C CE  . MET A 1 18  ? 113.007 89.646  91.542  1.00 61.32  ? 18  MET A CE  1 
ATOM 113  N N   . ILE A 1 19  ? 108.591 93.189  90.401  1.00 60.28  ? 19  ILE A N   1 
ATOM 114  C CA  . ILE A 1 19  ? 108.578 94.593  90.003  1.00 54.90  ? 19  ILE A CA  1 
ATOM 115  C C   . ILE A 1 19  ? 108.458 95.499  91.223  1.00 63.80  ? 19  ILE A C   1 
ATOM 116  O O   . ILE A 1 19  ? 109.149 96.520  91.323  1.00 63.17  ? 19  ILE A O   1 
ATOM 117  C CB  . ILE A 1 19  ? 107.468 94.855  88.971  1.00 42.60  ? 19  ILE A CB  1 
ATOM 118  C CG1 . ILE A 1 19  ? 107.794 94.117  87.672  1.00 45.30  ? 19  ILE A CG1 1 
ATOM 119  C CG2 . ILE A 1 19  ? 107.312 96.343  88.722  1.00 51.86  ? 19  ILE A CG2 1 
ATOM 120  C CD1 . ILE A 1 19  ? 106.674 94.087  86.682  1.00 51.59  ? 19  ILE A CD1 1 
ATOM 121  N N   . ASP A 1 20  ? 107.584 95.143  92.170  1.00 54.41  ? 20  ASP A N   1 
ATOM 122  C CA  . ASP A 1 20  ? 107.483 95.926  93.398  1.00 44.33  ? 20  ASP A CA  1 
ATOM 123  C C   . ASP A 1 20  ? 108.783 95.890  94.184  1.00 42.08  ? 20  ASP A C   1 
ATOM 124  O O   . ASP A 1 20  ? 109.106 96.851  94.890  1.00 52.37  ? 20  ASP A O   1 
ATOM 125  C CB  . ASP A 1 20  ? 106.338 95.404  94.266  1.00 52.99  ? 20  ASP A CB  1 
ATOM 126  C CG  . ASP A 1 20  ? 104.981 95.715  93.686  1.00 59.26  ? 20  ASP A CG  1 
ATOM 127  O OD1 . ASP A 1 20  ? 104.916 96.563  92.777  1.00 53.57  ? 20  ASP A OD1 1 
ATOM 128  O OD2 . ASP A 1 20  ? 103.982 95.116  94.135  1.00 65.40  ? 20  ASP A OD2 1 
ATOM 129  N N   . ARG A 1 21  ? 109.534 94.792  94.087  1.00 43.65  ? 21  ARG A N   1 
ATOM 130  C CA  . ARG A 1 21  ? 110.836 94.738  94.740  1.00 49.83  ? 21  ARG A CA  1 
ATOM 131  C C   . ARG A 1 21  ? 111.787 95.775  94.156  1.00 51.50  ? 21  ARG A C   1 
ATOM 132  O O   . ARG A 1 21  ? 112.718 96.220  94.839  1.00 54.07  ? 21  ARG A O   1 
ATOM 133  C CB  . ARG A 1 21  ? 111.428 93.334  94.616  1.00 52.13  ? 21  ARG A CB  1 
ATOM 134  C CG  . ARG A 1 21  ? 112.639 93.088  95.499  1.00 51.32  ? 21  ARG A CG  1 
ATOM 135  C CD  . ARG A 1 21  ? 112.925 91.604  95.635  1.00 52.74  ? 21  ARG A CD  1 
ATOM 136  N NE  . ARG A 1 21  ? 111.784 90.877  96.179  1.00 52.19  ? 21  ARG A NE  1 
ATOM 137  C CZ  . ARG A 1 21  ? 111.762 89.568  96.390  1.00 57.99  ? 21  ARG A CZ  1 
ATOM 138  N NH1 . ARG A 1 21  ? 112.808 88.806  96.114  1.00 57.90  ? 21  ARG A NH1 1 
ATOM 139  N NH2 . ARG A 1 21  ? 110.664 89.010  96.890  1.00 57.27  ? 21  ARG A NH2 1 
ATOM 140  N N   . ASN A 1 22  ? 111.570 96.174  92.902  1.00 53.57  ? 22  ASN A N   1 
ATOM 141  C CA  . ASN A 1 22  ? 112.392 97.188  92.255  1.00 51.04  ? 22  ASN A CA  1 
ATOM 142  C C   . ASN A 1 22  ? 111.779 98.580  92.300  1.00 58.28  ? 22  ASN A C   1 
ATOM 143  O O   . ASN A 1 22  ? 112.521 99.567  92.302  1.00 62.65  ? 22  ASN A O   1 
ATOM 144  C CB  . ASN A 1 22  ? 112.651 96.810  90.792  1.00 53.78  ? 22  ASN A CB  1 
ATOM 145  C CG  . ASN A 1 22  ? 113.593 95.630  90.652  1.00 61.94  ? 22  ASN A CG  1 
ATOM 146  O OD1 . ASN A 1 22  ? 114.382 95.340  91.550  1.00 63.62  ? 22  ASN A OD1 1 
ATOM 147  N ND2 . ASN A 1 22  ? 113.519 94.946  89.515  1.00 64.41  ? 22  ASN A ND2 1 
ATOM 148  N N   . LEU A 1 23  ? 110.447 98.690  92.322  1.00 56.60  ? 23  LEU A N   1 
ATOM 149  C CA  . LEU A 1 23  ? 109.825 99.983  92.590  1.00 53.32  ? 23  LEU A CA  1 
ATOM 150  C C   . LEU A 1 23  ? 110.156 100.469 93.994  1.00 52.41  ? 23  LEU A C   1 
ATOM 151  O O   . LEU A 1 23  ? 110.428 101.657 94.202  1.00 54.86  ? 23  LEU A O   1 
ATOM 152  C CB  . LEU A 1 23  ? 108.313 99.896  92.396  1.00 42.52  ? 23  LEU A CB  1 
ATOM 153  C CG  . LEU A 1 23  ? 107.827 99.515  90.998  1.00 43.31  ? 23  LEU A CG  1 
ATOM 154  C CD1 . LEU A 1 23  ? 106.316 99.419  90.982  1.00 51.28  ? 23  LEU A CD1 1 
ATOM 155  C CD2 . LEU A 1 23  ? 108.309 100.525 89.975  1.00 44.98  ? 23  LEU A CD2 1 
ATOM 156  N N   . ARG A 1 24  ? 110.124 99.562  94.973  1.00 53.78  ? 24  ARG A N   1 
ATOM 157  C CA  . ARG A 1 24  ? 110.480 99.931  96.338  1.00 52.86  ? 24  ARG A CA  1 
ATOM 158  C C   . ARG A 1 24  ? 111.937 100.363 96.429  1.00 56.63  ? 24  ARG A C   1 
ATOM 159  O O   . ARG A 1 24  ? 112.263 101.333 97.124  1.00 68.42  ? 24  ARG A O   1 
ATOM 160  C CB  . ARG A 1 24  ? 110.202 98.763  97.283  1.00 52.77  ? 24  ARG A CB  1 
ATOM 161  C CG  . ARG A 1 24  ? 110.599 99.015  98.728  1.00 55.49  ? 24  ARG A CG  1 
ATOM 162  C CD  . ARG A 1 24  ? 110.535 97.735  99.548  1.00 54.45  ? 24  ARG A CD  1 
ATOM 163  N NE  . ARG A 1 24  ? 109.178 97.211  99.646  1.00 53.00  ? 24  ARG A NE  1 
ATOM 164  C CZ  . ARG A 1 24  ? 108.720 96.175  98.955  1.00 59.02  ? 24  ARG A CZ  1 
ATOM 165  N NH1 . ARG A 1 24  ? 109.489 95.520  98.101  1.00 63.23  ? 24  ARG A NH1 1 
ATOM 166  N NH2 . ARG A 1 24  ? 107.460 95.787  99.127  1.00 62.19  ? 24  ARG A NH2 1 
ATOM 167  N N   . GLU A 1 25  ? 112.829 99.653  95.735  1.00 53.42  ? 25  GLU A N   1 
ATOM 168  C CA  . GLU A 1 25  ? 114.243 100.014 95.765  1.00 58.05  ? 25  GLU A CA  1 
ATOM 169  C C   . GLU A 1 25  ? 114.484 101.378 95.129  1.00 63.70  ? 25  GLU A C   1 
ATOM 170  O O   . GLU A 1 25  ? 115.279 102.174 95.640  1.00 75.45  ? 25  GLU A O   1 
ATOM 171  C CB  . GLU A 1 25  ? 115.068 98.940  95.059  1.00 68.02  ? 25  GLU A CB  1 
ATOM 172  C CG  . GLU A 1 25  ? 116.556 99.234  95.001  1.00 70.28  ? 25  GLU A CG  1 
ATOM 173  C CD  . GLU A 1 25  ? 117.334 98.157  94.268  1.00 73.09  ? 25  GLU A CD  1 
ATOM 174  O OE1 . GLU A 1 25  ? 116.715 97.158  93.843  1.00 72.66  ? 25  GLU A OE1 1 
ATOM 175  O OE2 . GLU A 1 25  ? 118.564 98.308  94.119  1.00 73.26  ? 25  GLU A OE2 1 
ATOM 176  N N   . ASP A 1 26  ? 113.805 101.667 94.017  1.00 58.58  ? 26  ASP A N   1 
ATOM 177  C CA  . ASP A 1 26  ? 113.976 102.961 93.366  1.00 65.92  ? 26  ASP A CA  1 
ATOM 178  C C   . ASP A 1 26  ? 113.216 104.063 94.094  1.00 70.42  ? 26  ASP A C   1 
ATOM 179  O O   . ASP A 1 26  ? 113.690 105.203 94.165  1.00 73.97  ? 26  ASP A O   1 
ATOM 180  C CB  . ASP A 1 26  ? 113.531 102.875 91.905  1.00 69.55  ? 26  ASP A CB  1 
ATOM 181  C CG  . ASP A 1 26  ? 114.457 102.015 91.067  1.00 73.50  ? 26  ASP A CG  1 
ATOM 182  O OD1 . ASP A 1 26  ? 115.654 101.921 91.411  1.00 72.09  ? 26  ASP A OD1 1 
ATOM 183  O OD2 . ASP A 1 26  ? 113.991 101.434 90.065  1.00 75.71  ? 26  ASP A OD2 1 
ATOM 184  N N   . GLY A 1 27  ? 112.037 103.747 94.631  1.00 65.82  ? 27  GLY A N   1 
ATOM 185  C CA  . GLY A 1 27  ? 111.255 104.759 95.323  1.00 60.79  ? 27  GLY A CA  1 
ATOM 186  C C   . GLY A 1 27  ? 111.919 105.241 96.597  1.00 59.69  ? 27  GLY A C   1 
ATOM 187  O O   . GLY A 1 27  ? 111.823 106.419 96.954  1.00 61.17  ? 27  GLY A O   1 
ATOM 188  N N   . GLU A 1 28  ? 112.601 104.337 97.302  1.00 65.95  ? 28  GLU A N   1 
ATOM 189  C CA  . GLU A 1 28  ? 113.322 104.724 98.510  1.00 66.47  ? 28  GLU A CA  1 
ATOM 190  C C   . GLU A 1 28  ? 114.573 105.518 98.164  1.00 75.31  ? 28  GLU A C   1 
ATOM 191  O O   . GLU A 1 28  ? 114.951 106.442 98.894  1.00 81.00  ? 28  GLU A O   1 
ATOM 192  C CB  . GLU A 1 28  ? 113.674 103.488 99.336  1.00 61.24  ? 28  GLU A CB  1 
ATOM 193  C CG  . GLU A 1 28  ? 112.468 102.779 99.930  1.00 65.88  ? 28  GLU A CG  1 
ATOM 194  C CD  . GLU A 1 28  ? 112.850 101.548 100.727 1.00 70.91  ? 28  GLU A CD  1 
ATOM 195  O OE1 . GLU A 1 28  ? 114.061 101.258 100.833 1.00 76.17  ? 28  GLU A OE1 1 
ATOM 196  O OE2 . GLU A 1 28  ? 111.940 100.869 101.247 1.00 71.23  ? 28  GLU A OE2 1 
ATOM 197  N N   . LYS A 1 29  ? 115.231 105.170 97.057  1.00 72.40  ? 29  LYS A N   1 
ATOM 198  C CA  . LYS A 1 29  ? 116.399 105.928 96.628  1.00 69.65  ? 29  LYS A CA  1 
ATOM 199  C C   . LYS A 1 29  ? 116.014 107.345 96.226  1.00 73.72  ? 29  LYS A C   1 
ATOM 200  O O   . LYS A 1 29  ? 116.773 108.292 96.466  1.00 79.01  ? 29  LYS A O   1 
ATOM 201  C CB  . LYS A 1 29  ? 117.079 105.208 95.463  1.00 67.78  ? 29  LYS A CB  1 
ATOM 202  C CG  . LYS A 1 29  ? 118.354 105.864 94.964  1.00 70.45  ? 29  LYS A CG  1 
ATOM 203  C CD  . LYS A 1 29  ? 118.974 105.050 93.840  1.00 74.40  ? 29  LYS A CD  1 
ATOM 204  C CE  . LYS A 1 29  ? 120.237 105.703 93.308  1.00 75.06  ? 29  LYS A CE  1 
ATOM 205  N NZ  . LYS A 1 29  ? 120.844 104.904 92.207  1.00 76.10  ? 29  LYS A NZ  1 
ATOM 206  N N   . ALA A 1 30  ? 114.839 107.515 95.616  1.00 72.53  ? 30  ALA A N   1 
ATOM 207  C CA  . ALA A 1 30  ? 114.373 108.854 95.278  1.00 73.27  ? 30  ALA A CA  1 
ATOM 208  C C   . ALA A 1 30  ? 113.889 109.627 96.498  1.00 73.86  ? 30  ALA A C   1 
ATOM 209  O O   . ALA A 1 30  ? 113.895 110.862 96.474  1.00 72.25  ? 30  ALA A O   1 
ATOM 210  C CB  . ALA A 1 30  ? 113.257 108.776 94.236  1.00 68.68  ? 30  ALA A CB  1 
ATOM 211  N N   . ALA A 1 31  ? 113.469 108.934 97.561  1.00 74.94  ? 31  ALA A N   1 
ATOM 212  C CA  . ALA A 1 31  ? 112.922 109.616 98.727  1.00 71.85  ? 31  ALA A CA  1 
ATOM 213  C C   . ALA A 1 31  ? 113.991 110.273 99.587  1.00 71.58  ? 31  ALA A C   1 
ATOM 214  O O   . ALA A 1 31  ? 113.686 111.231 100.305 1.00 77.10  ? 31  ALA A O   1 
ATOM 215  C CB  . ALA A 1 31  ? 112.113 108.635 99.578  1.00 70.59  ? 31  ALA A CB  1 
ATOM 216  N N   . ARG A 1 32  ? 115.229 109.789 99.529  1.00 73.39  ? 32  ARG A N   1 
ATOM 217  C CA  . ARG A 1 32  ? 116.312 110.327 100.341 1.00 78.74  ? 32  ARG A CA  1 
ATOM 218  C C   . ARG A 1 32  ? 117.112 111.393 99.609  1.00 78.77  ? 32  ARG A C   1 
ATOM 219  O O   . ARG A 1 32  ? 118.047 111.957 100.187 1.00 83.36  ? 32  ARG A O   1 
ATOM 220  C CB  . ARG A 1 32  ? 117.237 109.193 100.796 1.00 81.42  ? 32  ARG A CB  1 
ATOM 221  C CG  . ARG A 1 32  ? 116.597 108.258 101.812 1.00 84.35  ? 32  ARG A CG  1 
ATOM 222  C CD  . ARG A 1 32  ? 117.267 106.895 101.826 1.00 84.45  ? 32  ARG A CD  1 
ATOM 223  N NE  . ARG A 1 32  ? 116.292 105.814 101.734 1.00 82.45  ? 32  ARG A NE  1 
ATOM 224  C CZ  . ARG A 1 32  ? 116.246 104.774 102.556 1.00 82.57  ? 32  ARG A CZ  1 
ATOM 225  N NH1 . ARG A 1 32  ? 117.110 104.639 103.548 1.00 80.21  ? 32  ARG A NH1 1 
ATOM 226  N NH2 . ARG A 1 32  ? 115.308 103.848 102.378 1.00 85.69  ? 32  ARG A NH2 1 
ATOM 227  N N   . GLU A 1 33  ? 116.767 111.674 98.359  1.00 73.04  ? 33  GLU A N   1 
ATOM 228  C CA  . GLU A 1 33  ? 117.431 112.670 97.534  1.00 74.42  ? 33  GLU A CA  1 
ATOM 229  C C   . GLU A 1 33  ? 116.661 113.985 97.581  1.00 74.21  ? 33  GLU A C   1 
ATOM 230  O O   . GLU A 1 33  ? 115.467 114.024 97.888  1.00 73.63  ? 33  GLU A O   1 
ATOM 231  C CB  . GLU A 1 33  ? 117.572 112.170 96.095  1.00 73.17  ? 33  GLU A CB  1 
ATOM 232  C CG  . GLU A 1 33  ? 118.546 111.005 95.970  1.00 77.13  ? 33  GLU A CG  1 
ATOM 233  C CD  . GLU A 1 33  ? 118.830 110.619 94.534  1.00 80.27  ? 33  GLU A CD  1 
ATOM 234  O OE1 . GLU A 1 33  ? 118.237 111.232 93.626  1.00 80.64  ? 33  GLU A OE1 1 
ATOM 235  O OE2 . GLU A 1 33  ? 119.649 109.702 94.314  1.00 83.96  ? 33  GLU A OE2 1 
ATOM 236  N N   . VAL A 1 34  ? 117.364 115.070 97.273  1.00 61.96  ? 34  VAL A N   1 
ATOM 237  C CA  . VAL A 1 34  ? 116.837 116.421 97.416  1.00 59.94  ? 34  VAL A CA  1 
ATOM 238  C C   . VAL A 1 34  ? 116.539 116.976 96.032  1.00 64.48  ? 34  VAL A C   1 
ATOM 239  O O   . VAL A 1 34  ? 117.394 116.934 95.138  1.00 58.32  ? 34  VAL A O   1 
ATOM 240  C CB  . VAL A 1 34  ? 117.820 117.330 98.173  1.00 56.15  ? 34  VAL A CB  1 
ATOM 241  C CG1 . VAL A 1 34  ? 117.327 118.767 98.169  1.00 62.87  ? 34  VAL A CG1 1 
ATOM 242  C CG2 . VAL A 1 34  ? 118.011 116.830 99.596  1.00 49.27  ? 34  VAL A CG2 1 
ATOM 243  N N   . LYS A 1 35  ? 115.326 117.491 95.858  1.00 53.55  ? 35  LYS A N   1 
ATOM 244  C CA  . LYS A 1 35  ? 114.887 118.104 94.613  1.00 52.67  ? 35  LYS A CA  1 
ATOM 245  C C   . LYS A 1 35  ? 114.767 119.604 94.835  1.00 56.85  ? 35  LYS A C   1 
ATOM 246  O O   . LYS A 1 35  ? 114.047 120.045 95.737  1.00 63.91  ? 35  LYS A O   1 
ATOM 247  C CB  . LYS A 1 35  ? 113.547 117.520 94.163  1.00 52.23  ? 35  LYS A CB  1 
ATOM 248  C CG  . LYS A 1 35  ? 113.599 116.057 93.760  1.00 63.94  ? 35  LYS A CG  1 
ATOM 249  C CD  . LYS A 1 35  ? 112.222 115.553 93.354  1.00 63.46  ? 35  LYS A CD  1 
ATOM 250  C CE  . LYS A 1 35  ? 112.266 114.093 92.927  1.00 61.34  ? 35  LYS A CE  1 
ATOM 251  N NZ  . LYS A 1 35  ? 110.915 113.593 92.550  1.00 58.44  ? 35  LYS A NZ  1 
ATOM 252  N N   . LEU A 1 36  ? 115.478 120.383 94.024  1.00 47.19  ? 36  LEU A N   1 
ATOM 253  C CA  . LEU A 1 36  ? 115.471 121.834 94.120  1.00 26.65  ? 36  LEU A CA  1 
ATOM 254  C C   . LEU A 1 36  ? 114.994 122.431 92.805  1.00 31.26  ? 36  LEU A C   1 
ATOM 255  O O   . LEU A 1 36  ? 115.420 122.006 91.728  1.00 48.89  ? 36  LEU A O   1 
ATOM 256  C CB  . LEU A 1 36  ? 116.864 122.370 94.464  1.00 34.50  ? 36  LEU A CB  1 
ATOM 257  C CG  . LEU A 1 36  ? 117.424 121.916 95.813  1.00 45.95  ? 36  LEU A CG  1 
ATOM 258  C CD1 . LEU A 1 36  ? 118.882 122.319 95.959  1.00 51.36  ? 36  LEU A CD1 1 
ATOM 259  C CD2 . LEU A 1 36  ? 116.594 122.488 96.947  1.00 44.88  ? 36  LEU A CD2 1 
ATOM 260  N N   . LEU A 1 37  ? 114.113 123.422 92.899  1.00 27.27  ? 37  LEU A N   1 
ATOM 261  C CA  . LEU A 1 37  ? 113.633 124.159 91.738  1.00 28.15  ? 37  LEU A CA  1 
ATOM 262  C C   . LEU A 1 37  ? 114.373 125.487 91.662  1.00 43.90  ? 37  LEU A C   1 
ATOM 263  O O   . LEU A 1 37  ? 114.261 126.317 92.571  1.00 59.68  ? 37  LEU A O   1 
ATOM 264  C CB  . LEU A 1 37  ? 112.125 124.383 91.818  1.00 29.78  ? 37  LEU A CB  1 
ATOM 265  C CG  . LEU A 1 37  ? 111.514 125.182 90.668  1.00 28.11  ? 37  LEU A CG  1 
ATOM 266  C CD1 . LEU A 1 37  ? 111.821 124.517 89.339  1.00 37.89  ? 37  LEU A CD1 1 
ATOM 267  C CD2 . LEU A 1 37  ? 110.016 125.330 90.862  1.00 36.34  ? 37  LEU A CD2 1 
ATOM 268  N N   . LEU A 1 38  ? 115.133 125.682 90.588  1.00 36.38  ? 38  LEU A N   1 
ATOM 269  C CA  . LEU A 1 38  ? 115.950 126.878 90.423  1.00 35.64  ? 38  LEU A CA  1 
ATOM 270  C C   . LEU A 1 38  ? 115.164 127.894 89.601  1.00 34.67  ? 38  LEU A C   1 
ATOM 271  O O   . LEU A 1 38  ? 114.904 127.678 88.413  1.00 49.16  ? 38  LEU A O   1 
ATOM 272  C CB  . LEU A 1 38  ? 117.279 126.531 89.760  1.00 39.82  ? 38  LEU A CB  1 
ATOM 273  C CG  . LEU A 1 38  ? 118.251 127.688 89.531  1.00 45.92  ? 38  LEU A CG  1 
ATOM 274  C CD1 . LEU A 1 38  ? 118.565 128.384 90.842  1.00 46.53  ? 38  LEU A CD1 1 
ATOM 275  C CD2 . LEU A 1 38  ? 119.523 127.183 88.874  1.00 50.14  ? 38  LEU A CD2 1 
ATOM 276  N N   . LEU A 1 39  ? 114.782 128.996 90.239  1.00 29.49  ? 39  LEU A N   1 
ATOM 277  C CA  . LEU A 1 39  ? 113.997 130.049 89.616  1.00 42.78  ? 39  LEU A CA  1 
ATOM 278  C C   . LEU A 1 39  ? 114.768 131.362 89.654  1.00 51.26  ? 39  LEU A C   1 
ATOM 279  O O   . LEU A 1 39  ? 115.730 131.522 90.409  1.00 61.76  ? 39  LEU A O   1 
ATOM 280  C CB  . LEU A 1 39  ? 112.639 130.210 90.311  1.00 45.33  ? 39  LEU A CB  1 
ATOM 281  C CG  . LEU A 1 39  ? 111.657 129.056 90.100  1.00 40.80  ? 39  LEU A CG  1 
ATOM 282  C CD1 . LEU A 1 39  ? 110.407 129.248 90.941  1.00 47.74  ? 39  LEU A CD1 1 
ATOM 283  C CD2 . LEU A 1 39  ? 111.299 128.929 88.627  1.00 36.57  ? 39  LEU A CD2 1 
ATOM 284  N N   . GLY A 1 40  ? 114.336 132.298 88.827  1.00 63.83  ? 40  GLY A N   1 
ATOM 285  C CA  . GLY A 1 40  ? 114.979 133.594 88.713  1.00 65.14  ? 40  GLY A CA  1 
ATOM 286  C C   . GLY A 1 40  ? 115.073 134.041 87.267  1.00 72.56  ? 40  GLY A C   1 
ATOM 287  O O   . GLY A 1 40  ? 114.977 133.250 86.329  1.00 74.27  ? 40  GLY A O   1 
ATOM 288  N N   . ALA A 1 41  ? 115.267 135.343 87.088  1.00 105.21 ? 41  ALA A N   1 
ATOM 289  C CA  . ALA A 1 41  ? 114.913 136.045 85.867  1.00 106.05 ? 41  ALA A CA  1 
ATOM 290  C C   . ALA A 1 41  ? 116.137 136.161 84.959  1.00 105.05 ? 41  ALA A C   1 
ATOM 291  O O   . ALA A 1 41  ? 117.194 135.580 85.220  1.00 104.78 ? 41  ALA A O   1 
ATOM 292  C CB  . ALA A 1 41  ? 114.323 137.415 86.204  1.00 102.43 ? 41  ALA A CB  1 
ATOM 293  N N   . GLY A 1 42  ? 115.990 136.911 83.870  1.00 114.38 ? 42  GLY A N   1 
ATOM 294  C CA  . GLY A 1 42  ? 117.100 137.106 82.950  1.00 115.51 ? 42  GLY A CA  1 
ATOM 295  C C   . GLY A 1 42  ? 118.192 137.949 83.583  1.00 119.05 ? 42  GLY A C   1 
ATOM 296  O O   . GLY A 1 42  ? 117.920 138.993 84.188  1.00 120.43 ? 42  GLY A O   1 
ATOM 297  N N   . GLU A 1 43  ? 119.440 137.495 83.442  1.00 117.07 ? 43  GLU A N   1 
ATOM 298  C CA  . GLU A 1 43  ? 120.609 138.172 84.010  1.00 115.88 ? 43  GLU A CA  1 
ATOM 299  C C   . GLU A 1 43  ? 120.458 138.365 85.517  1.00 114.67 ? 43  GLU A C   1 
ATOM 300  O O   . GLU A 1 43  ? 120.833 139.400 86.073  1.00 109.84 ? 43  GLU A O   1 
ATOM 301  C CB  . GLU A 1 43  ? 120.870 139.509 83.311  1.00 113.83 ? 43  GLU A CB  1 
ATOM 302  N N   . SER A 1 44  ? 119.902 137.354 86.181  1.00 108.52 ? 44  SER A N   1 
ATOM 303  C CA  . SER A 1 44  ? 119.686 137.365 87.621  1.00 108.85 ? 44  SER A CA  1 
ATOM 304  C C   . SER A 1 44  ? 120.727 136.546 88.370  1.00 110.43 ? 44  SER A C   1 
ATOM 305  O O   . SER A 1 44  ? 120.581 136.330 89.578  1.00 112.30 ? 44  SER A O   1 
ATOM 306  C CB  . SER A 1 44  ? 118.282 136.853 87.948  1.00 105.19 ? 44  SER A CB  1 
ATOM 307  O OG  . SER A 1 44  ? 118.096 135.533 87.466  1.00 105.63 ? 44  SER A OG  1 
ATOM 308  N N   . GLY A 1 45  ? 121.771 136.084 87.685  1.00 107.69 ? 45  GLY A N   1 
ATOM 309  C CA  . GLY A 1 45  ? 122.764 135.233 88.304  1.00 107.33 ? 45  GLY A CA  1 
ATOM 310  C C   . GLY A 1 45  ? 122.383 133.773 88.386  1.00 108.09 ? 45  GLY A C   1 
ATOM 311  O O   . GLY A 1 45  ? 123.090 133.002 89.044  1.00 111.37 ? 45  GLY A O   1 
ATOM 312  N N   . LYS A 1 46  ? 121.281 133.373 87.746  1.00 95.30  ? 46  LYS A N   1 
ATOM 313  C CA  . LYS A 1 46  ? 120.845 131.981 87.799  1.00 95.11  ? 46  LYS A CA  1 
ATOM 314  C C   . LYS A 1 46  ? 121.898 131.045 87.221  1.00 96.39  ? 46  LYS A C   1 
ATOM 315  O O   . LYS A 1 46  ? 122.172 129.980 87.787  1.00 94.77  ? 46  LYS A O   1 
ATOM 316  C CB  . LYS A 1 46  ? 119.520 131.822 87.054  1.00 91.78  ? 46  LYS A CB  1 
ATOM 317  C CG  . LYS A 1 46  ? 118.841 130.478 87.269  1.00 90.68  ? 46  LYS A CG  1 
ATOM 318  C CD  . LYS A 1 46  ? 117.691 130.258 86.294  1.00 93.41  ? 46  LYS A CD  1 
ATOM 319  C CE  . LYS A 1 46  ? 117.949 130.925 84.951  1.00 93.33  ? 46  LYS A CE  1 
ATOM 320  N NZ  . LYS A 1 46  ? 117.019 132.059 84.699  1.00 95.31  ? 46  LYS A NZ  1 
ATOM 321  N N   . ASN A 1 47  ? 122.502 131.424 86.094  1.00 104.53 ? 47  ASN A N   1 
ATOM 322  C CA  . ASN A 1 47  ? 123.505 130.579 85.457  1.00 105.86 ? 47  ASN A CA  1 
ATOM 323  C C   . ASN A 1 47  ? 124.845 130.612 86.178  1.00 106.88 ? 47  ASN A C   1 
ATOM 324  O O   . ASN A 1 47  ? 125.630 129.668 86.037  1.00 104.57 ? 47  ASN A O   1 
ATOM 325  C CB  . ASN A 1 47  ? 123.693 130.995 83.997  1.00 104.99 ? 47  ASN A CB  1 
ATOM 326  C CG  . ASN A 1 47  ? 122.399 130.948 83.207  1.00 104.83 ? 47  ASN A CG  1 
ATOM 327  O OD1 . ASN A 1 47  ? 121.957 131.957 82.657  1.00 104.09 ? 47  ASN A OD1 1 
ATOM 328  N ND2 . ASN A 1 47  ? 121.783 129.773 83.150  1.00 105.41 ? 47  ASN A ND2 1 
ATOM 329  N N   . THR A 1 48  ? 125.128 131.672 86.939  1.00 112.76 ? 48  THR A N   1 
ATOM 330  C CA  . THR A 1 48  ? 126.385 131.731 87.678  1.00 112.41 ? 48  THR A CA  1 
ATOM 331  C C   . THR A 1 48  ? 126.402 130.715 88.814  1.00 111.83 ? 48  THR A C   1 
ATOM 332  O O   . THR A 1 48  ? 127.455 130.149 89.132  1.00 112.03 ? 48  THR A O   1 
ATOM 333  C CB  . THR A 1 48  ? 126.614 133.142 88.218  1.00 109.31 ? 48  THR A CB  1 
ATOM 334  N N   . ILE A 1 49  ? 125.248 130.481 89.443  1.00 108.57 ? 49  ILE A N   1 
ATOM 335  C CA  . ILE A 1 49  ? 125.170 129.499 90.520  1.00 109.02 ? 49  ILE A CA  1 
ATOM 336  C C   . ILE A 1 49  ? 125.440 128.098 89.985  1.00 110.29 ? 49  ILE A C   1 
ATOM 337  O O   . ILE A 1 49  ? 126.132 127.296 90.624  1.00 110.06 ? 49  ILE A O   1 
ATOM 338  C CB  . ILE A 1 49  ? 123.803 129.588 91.222  1.00 108.15 ? 49  ILE A CB  1 
ATOM 339  C CG1 . ILE A 1 49  ? 123.567 131.004 91.753  1.00 108.07 ? 49  ILE A CG1 1 
ATOM 340  C CG2 . ILE A 1 49  ? 123.709 128.571 92.348  1.00 110.12 ? 49  ILE A CG2 1 
ATOM 341  C CD1 . ILE A 1 49  ? 124.617 131.472 92.737  1.00 108.61 ? 49  ILE A CD1 1 
ATOM 342  N N   . VAL A 1 50  ? 124.891 127.781 88.809  1.00 116.89 ? 50  VAL A N   1 
ATOM 343  C CA  . VAL A 1 50  ? 125.136 126.483 88.186  1.00 118.42 ? 50  VAL A CA  1 
ATOM 344  C C   . VAL A 1 50  ? 126.617 126.307 87.876  1.00 120.53 ? 50  VAL A C   1 
ATOM 345  O O   . VAL A 1 50  ? 127.167 125.206 87.998  1.00 121.16 ? 50  VAL A O   1 
ATOM 346  C CB  . VAL A 1 50  ? 124.271 126.329 86.921  1.00 120.08 ? 50  VAL A CB  1 
ATOM 347  C CG1 . VAL A 1 50  ? 124.434 124.938 86.327  1.00 120.67 ? 50  VAL A CG1 1 
ATOM 348  C CG2 . VAL A 1 50  ? 122.811 126.611 87.237  1.00 115.72 ? 50  VAL A CG2 1 
ATOM 349  N N   . LYS A 1 51  ? 127.286 127.389 87.471  1.00 125.56 ? 51  LYS A N   1 
ATOM 350  C CA  . LYS A 1 51  ? 128.710 127.321 87.157  1.00 126.50 ? 51  LYS A CA  1 
ATOM 351  C C   . LYS A 1 51  ? 129.560 126.976 88.372  1.00 126.71 ? 51  LYS A C   1 
ATOM 352  O O   . LYS A 1 51  ? 130.707 126.543 88.208  1.00 125.09 ? 51  LYS A O   1 
ATOM 353  C CB  . LYS A 1 51  ? 129.178 128.647 86.555  1.00 124.61 ? 51  LYS A CB  1 
ATOM 354  N N   . GLN A 1 52  ? 129.034 127.157 89.583  1.00 130.40 ? 52  GLN A N   1 
ATOM 355  C CA  . GLN A 1 52  ? 129.753 126.806 90.799  1.00 130.14 ? 52  GLN A CA  1 
ATOM 356  C C   . GLN A 1 52  ? 129.400 125.421 91.325  1.00 130.25 ? 52  GLN A C   1 
ATOM 357  O O   . GLN A 1 52  ? 130.127 124.896 92.175  1.00 130.71 ? 52  GLN A O   1 
ATOM 358  C CB  . GLN A 1 52  ? 129.484 127.848 91.892  1.00 126.85 ? 52  GLN A CB  1 
ATOM 359  C CG  . GLN A 1 52  ? 129.971 129.246 91.547  1.00 128.03 ? 52  GLN A CG  1 
ATOM 360  C CD  . GLN A 1 52  ? 129.836 130.213 92.706  1.00 129.39 ? 52  GLN A CD  1 
ATOM 361  O OE1 . GLN A 1 52  ? 129.502 129.820 93.823  1.00 128.31 ? 52  GLN A OE1 1 
ATOM 362  N NE2 . GLN A 1 52  ? 130.097 131.489 92.445  1.00 130.11 ? 52  GLN A NE2 1 
ATOM 363  N N   . MET A 1 53  ? 128.313 124.821 90.846  1.00 132.77 ? 53  MET A N   1 
ATOM 364  C CA  . MET A 1 53  ? 127.878 123.488 91.263  1.00 134.04 ? 53  MET A CA  1 
ATOM 365  C C   . MET A 1 53  ? 127.874 122.594 90.027  1.00 133.93 ? 53  MET A C   1 
ATOM 366  O O   . MET A 1 53  ? 126.842 122.408 89.379  1.00 132.56 ? 53  MET A O   1 
ATOM 367  C CB  . MET A 1 53  ? 126.498 123.537 91.936  1.00 133.19 ? 53  MET A CB  1 
ATOM 368  C CG  . MET A 1 53  ? 126.374 124.578 93.034  1.00 131.96 ? 53  MET A CG  1 
ATOM 369  S SD  . MET A 1 53  ? 124.698 124.692 93.688  1.00 137.16 ? 53  MET A SD  1 
ATOM 370  C CE  . MET A 1 53  ? 124.876 126.049 94.842  1.00 130.24 ? 53  MET A CE  1 
ATOM 371  N N   . LYS A 1 54  ? 129.037 122.039 89.705  1.00 135.29 ? 54  LYS A N   1 
ATOM 372  C CA  . LYS A 1 54  ? 129.173 121.163 88.547  1.00 134.82 ? 54  LYS A CA  1 
ATOM 373  C C   . LYS A 1 54  ? 129.424 119.722 88.978  1.00 133.99 ? 54  LYS A C   1 
ATOM 374  O O   . LYS A 1 54  ? 130.211 119.465 89.889  1.00 133.59 ? 54  LYS A O   1 
ATOM 375  C CB  . LYS A 1 54  ? 130.304 121.646 87.638  1.00 133.54 ? 54  LYS A CB  1 
ATOM 376  N N   . THR A 1 182 ? 117.753 120.482 75.725  1.00 78.23  ? 182 THR A N   1 
ATOM 377  C CA  . THR A 1 182 ? 116.319 120.273 75.569  1.00 79.60  ? 182 THR A CA  1 
ATOM 378  C C   . THR A 1 182 ? 115.527 121.392 76.241  1.00 79.62  ? 182 THR A C   1 
ATOM 379  O O   . THR A 1 182 ? 115.881 122.566 76.132  1.00 79.81  ? 182 THR A O   1 
ATOM 380  C CB  . THR A 1 182 ? 115.880 118.918 76.156  1.00 80.01  ? 182 THR A CB  1 
ATOM 381  N N   . GLY A 1 183 ? 114.456 121.020 76.938  1.00 80.13  ? 183 GLY A N   1 
ATOM 382  C CA  . GLY A 1 183 ? 113.595 121.995 77.578  1.00 80.19  ? 183 GLY A CA  1 
ATOM 383  C C   . GLY A 1 183 ? 114.000 122.285 79.009  1.00 78.82  ? 183 GLY A C   1 
ATOM 384  O O   . GLY A 1 183 ? 114.184 123.444 79.389  1.00 82.31  ? 183 GLY A O   1 
ATOM 385  N N   . ILE A 1 184 ? 114.134 121.235 79.813  1.00 55.45  ? 184 ILE A N   1 
ATOM 386  C CA  . ILE A 1 184 ? 114.505 121.351 81.217  1.00 51.87  ? 184 ILE A CA  1 
ATOM 387  C C   . ILE A 1 184 ? 115.931 120.844 81.374  1.00 59.69  ? 184 ILE A C   1 
ATOM 388  O O   . ILE A 1 184 ? 116.303 119.817 80.795  1.00 65.83  ? 184 ILE A O   1 
ATOM 389  C CB  . ILE A 1 184 ? 113.530 120.575 82.127  1.00 50.13  ? 184 ILE A CB  1 
ATOM 390  C CG1 . ILE A 1 184 ? 114.008 120.598 83.580  1.00 58.27  ? 184 ILE A CG1 1 
ATOM 391  C CG2 . ILE A 1 184 ? 113.355 119.145 81.637  1.00 59.02  ? 184 ILE A CG2 1 
ATOM 392  C CD1 . ILE A 1 184 ? 113.048 119.942 84.546  1.00 60.22  ? 184 ILE A CD1 1 
ATOM 393  N N   . VAL A 1 185 ? 116.735 121.575 82.140  1.00 68.95  ? 185 VAL A N   1 
ATOM 394  C CA  . VAL A 1 185 ? 118.137 121.238 82.354  1.00 66.98  ? 185 VAL A CA  1 
ATOM 395  C C   . VAL A 1 185 ? 118.281 120.761 83.791  1.00 66.40  ? 185 VAL A C   1 
ATOM 396  O O   . VAL A 1 185 ? 118.233 121.563 84.733  1.00 69.26  ? 185 VAL A O   1 
ATOM 397  C CB  . VAL A 1 185 ? 119.063 122.427 82.066  1.00 66.89  ? 185 VAL A CB  1 
ATOM 398  C CG1 . VAL A 1 185 ? 120.515 122.038 82.301  1.00 67.39  ? 185 VAL A CG1 1 
ATOM 399  C CG2 . VAL A 1 185 ? 118.865 122.916 80.639  1.00 64.30  ? 185 VAL A CG2 1 
ATOM 400  N N   . GLU A 1 186 ? 118.454 119.454 83.960  1.00 71.81  ? 186 GLU A N   1 
ATOM 401  C CA  . GLU A 1 186 ? 118.609 118.851 85.274  1.00 69.58  ? 186 GLU A CA  1 
ATOM 402  C C   . GLU A 1 186 ? 120.093 118.710 85.586  1.00 76.91  ? 186 GLU A C   1 
ATOM 403  O O   . GLU A 1 186 ? 120.861 118.210 84.758  1.00 85.69  ? 186 GLU A O   1 
ATOM 404  C CB  . GLU A 1 186 ? 117.914 117.491 85.323  1.00 70.11  ? 186 GLU A CB  1 
ATOM 405  C CG  . GLU A 1 186 ? 117.958 116.810 86.678  1.00 73.63  ? 186 GLU A CG  1 
ATOM 406  C CD  . GLU A 1 186 ? 117.211 115.490 86.687  1.00 80.62  ? 186 GLU A CD  1 
ATOM 407  O OE1 . GLU A 1 186 ? 116.694 115.089 85.623  1.00 75.87  ? 186 GLU A OE1 1 
ATOM 408  O OE2 . GLU A 1 186 ? 117.136 114.856 87.761  1.00 82.00  ? 186 GLU A OE2 1 
ATOM 409  N N   . THR A 1 187 ? 120.493 119.150 86.776  1.00 70.16  ? 187 THR A N   1 
ATOM 410  C CA  . THR A 1 187 ? 121.881 119.083 87.213  1.00 72.66  ? 187 THR A CA  1 
ATOM 411  C C   . THR A 1 187 ? 121.964 118.327 88.530  1.00 72.31  ? 187 THR A C   1 
ATOM 412  O O   . THR A 1 187 ? 121.205 118.611 89.463  1.00 75.39  ? 187 THR A O   1 
ATOM 413  C CB  . THR A 1 187 ? 122.475 120.486 87.369  1.00 72.32  ? 187 THR A CB  1 
ATOM 414  O OG1 . THR A 1 187 ? 122.333 121.206 86.139  1.00 70.27  ? 187 THR A OG1 1 
ATOM 415  C CG2 . THR A 1 187 ? 123.949 120.403 87.731  1.00 76.38  ? 187 THR A CG2 1 
ATOM 416  N N   . HIS A 1 188 ? 122.884 117.370 88.604  1.00 89.60  ? 188 HIS A N   1 
ATOM 417  C CA  . HIS A 1 188 ? 123.094 116.573 89.802  1.00 89.61  ? 188 HIS A CA  1 
ATOM 418  C C   . HIS A 1 188 ? 124.445 116.924 90.410  1.00 93.43  ? 188 HIS A C   1 
ATOM 419  O O   . HIS A 1 188 ? 125.413 117.176 89.686  1.00 93.35  ? 188 HIS A O   1 
ATOM 420  C CB  . HIS A 1 188 ? 123.052 115.078 89.476  1.00 91.41  ? 188 HIS A CB  1 
ATOM 421  C CG  . HIS A 1 188 ? 121.716 114.597 89.004  1.00 93.68  ? 188 HIS A CG  1 
ATOM 422  N ND1 . HIS A 1 188 ? 121.306 114.718 87.694  1.00 96.01  ? 188 HIS A ND1 1 
ATOM 423  C CD2 . HIS A 1 188 ? 120.697 113.996 89.663  1.00 90.93  ? 188 HIS A CD2 1 
ATOM 424  C CE1 . HIS A 1 188 ? 120.094 114.208 87.566  1.00 93.49  ? 188 HIS A CE1 1 
ATOM 425  N NE2 . HIS A 1 188 ? 119.701 113.765 88.746  1.00 91.24  ? 188 HIS A NE2 1 
ATOM 426  N N   . PHE A 1 189 ? 124.509 116.936 91.740  1.00 106.75 ? 189 PHE A N   1 
ATOM 427  C CA  . PHE A 1 189 ? 125.779 117.088 92.436  1.00 106.15 ? 189 PHE A CA  1 
ATOM 428  C C   . PHE A 1 189 ? 125.651 116.508 93.836  1.00 105.11 ? 189 PHE A C   1 
ATOM 429  O O   . PHE A 1 189 ? 124.551 116.387 94.381  1.00 101.78 ? 189 PHE A O   1 
ATOM 430  C CB  . PHE A 1 189 ? 126.237 118.553 92.484  1.00 101.21 ? 189 PHE A CB  1 
ATOM 431  C CG  . PHE A 1 189 ? 125.218 119.499 93.055  1.00 102.48 ? 189 PHE A CG  1 
ATOM 432  C CD1 . PHE A 1 189 ? 124.244 120.059 92.245  1.00 101.24 ? 189 PHE A CD1 1 
ATOM 433  C CD2 . PHE A 1 189 ? 125.250 119.847 94.395  1.00 103.70 ? 189 PHE A CD2 1 
ATOM 434  C CE1 . PHE A 1 189 ? 123.311 120.936 92.763  1.00 100.17 ? 189 PHE A CE1 1 
ATOM 435  C CE2 . PHE A 1 189 ? 124.319 120.725 94.918  1.00 102.75 ? 189 PHE A CE2 1 
ATOM 436  C CZ  . PHE A 1 189 ? 123.349 121.270 94.101  1.00 102.31 ? 189 PHE A CZ  1 
ATOM 437  N N   . THR A 1 190 ? 126.797 116.150 94.410  1.00 110.05 ? 190 THR A N   1 
ATOM 438  C CA  . THR A 1 190 ? 126.871 115.536 95.729  1.00 111.52 ? 190 THR A CA  1 
ATOM 439  C C   . THR A 1 190 ? 127.662 116.447 96.655  1.00 110.93 ? 190 THR A C   1 
ATOM 440  O O   . THR A 1 190 ? 128.752 116.906 96.298  1.00 111.08 ? 190 THR A O   1 
ATOM 441  C CB  . THR A 1 190 ? 127.525 114.152 95.661  1.00 111.82 ? 190 THR A CB  1 
ATOM 442  O OG1 . THR A 1 190 ? 126.778 113.312 94.772  1.00 107.20 ? 190 THR A OG1 1 
ATOM 443  C CG2 . THR A 1 190 ? 127.561 113.511 97.040  1.00 112.62 ? 190 THR A CG2 1 
ATOM 444  N N   . PHE A 1 191 ? 127.113 116.705 97.841  1.00 94.16  ? 191 PHE A N   1 
ATOM 445  C CA  . PHE A 1 191 ? 127.753 117.572 98.827  1.00 93.52  ? 191 PHE A CA  1 
ATOM 446  C C   . PHE A 1 191 ? 127.451 117.018 100.211 1.00 94.60  ? 191 PHE A C   1 
ATOM 447  O O   . PHE A 1 191 ? 126.301 117.060 100.660 1.00 93.96  ? 191 PHE A O   1 
ATOM 448  C CB  . PHE A 1 191 ? 127.262 119.015 98.693  1.00 93.80  ? 191 PHE A CB  1 
ATOM 449  C CG  . PHE A 1 191 ? 128.024 120.000 99.535  1.00 93.96  ? 191 PHE A CG  1 
ATOM 450  C CD1 . PHE A 1 191 ? 129.194 120.574 99.064  1.00 94.88  ? 191 PHE A CD1 1 
ATOM 451  C CD2 . PHE A 1 191 ? 127.569 120.357 100.793 1.00 93.89  ? 191 PHE A CD2 1 
ATOM 452  C CE1 . PHE A 1 191 ? 129.897 121.483 99.834  1.00 96.00  ? 191 PHE A CE1 1 
ATOM 453  C CE2 . PHE A 1 191 ? 128.267 121.264 101.567 1.00 98.88  ? 191 PHE A CE2 1 
ATOM 454  C CZ  . PHE A 1 191 ? 129.432 121.828 101.087 1.00 98.27  ? 191 PHE A CZ  1 
ATOM 455  N N   . LYS A 1 192 ? 128.483 116.500 100.880 1.00 99.15  ? 192 LYS A N   1 
ATOM 456  C CA  . LYS A 1 192 ? 128.376 115.954 102.234 1.00 99.83  ? 192 LYS A CA  1 
ATOM 457  C C   . LYS A 1 192 ? 127.340 114.828 102.295 1.00 102.01 ? 192 LYS A C   1 
ATOM 458  O O   . LYS A 1 192 ? 126.377 114.868 103.064 1.00 103.66 ? 192 LYS A O   1 
ATOM 459  C CB  . LYS A 1 192 ? 128.061 117.060 103.247 1.00 95.30  ? 192 LYS A CB  1 
ATOM 460  C CG  . LYS A 1 192 ? 129.188 118.063 103.427 1.00 95.42  ? 192 LYS A CG  1 
ATOM 461  C CD  . LYS A 1 192 ? 128.818 119.146 104.423 1.00 96.48  ? 192 LYS A CD  1 
ATOM 462  C CE  . LYS A 1 192 ? 129.961 120.129 104.614 1.00 98.13  ? 192 LYS A CE  1 
ATOM 463  N NZ  . LYS A 1 192 ? 129.611 121.216 105.569 1.00 97.12  ? 192 LYS A NZ  1 
ATOM 464  N N   . ASP A 1 193 ? 127.568 113.812 101.459 1.00 103.40 ? 193 ASP A N   1 
ATOM 465  C CA  . ASP A 1 193 ? 126.767 112.585 101.450 1.00 101.84 ? 193 ASP A CA  1 
ATOM 466  C C   . ASP A 1 193 ? 125.285 112.877 101.224 1.00 98.81  ? 193 ASP A C   1 
ATOM 467  O O   . ASP A 1 193 ? 124.409 112.228 101.800 1.00 97.99  ? 193 ASP A O   1 
ATOM 468  C CB  . ASP A 1 193 ? 126.970 111.786 102.740 1.00 102.68 ? 193 ASP A CB  1 
ATOM 469  C CG  . ASP A 1 193 ? 128.412 111.371 102.948 1.00 103.52 ? 193 ASP A CG  1 
ATOM 470  O OD1 . ASP A 1 193 ? 129.252 112.252 103.226 1.00 105.42 ? 193 ASP A OD1 1 
ATOM 471  O OD2 . ASP A 1 193 ? 128.707 110.163 102.832 1.00 101.35 ? 193 ASP A OD2 1 
ATOM 472  N N   . LEU A 1 194 ? 125.000 113.864 100.378 1.00 84.76  ? 194 LEU A N   1 
ATOM 473  C CA  . LEU A 1 194 ? 123.629 114.223 100.042 1.00 83.17  ? 194 LEU A CA  1 
ATOM 474  C C   . LEU A 1 194 ? 123.554 114.541 98.557  1.00 93.00  ? 194 LEU A C   1 
ATOM 475  O O   . LEU A 1 194 ? 124.348 115.340 98.052  1.00 94.10  ? 194 LEU A O   1 
ATOM 476  C CB  . LEU A 1 194 ? 123.144 115.417 100.872 1.00 85.12  ? 194 LEU A CB  1 
ATOM 477  C CG  . LEU A 1 194 ? 121.689 115.832 100.654 1.00 86.37  ? 194 LEU A CG  1 
ATOM 478  C CD1 . LEU A 1 194 ? 120.775 114.626 100.771 1.00 82.25  ? 194 LEU A CD1 1 
ATOM 479  C CD2 . LEU A 1 194 ? 121.282 116.904 101.653 1.00 87.31  ? 194 LEU A CD2 1 
ATOM 480  N N   . HIS A 1 195 ? 122.604 113.918 97.866  1.00 91.51  ? 195 HIS A N   1 
ATOM 481  C CA  . HIS A 1 195 ? 122.475 114.043 96.420  1.00 91.44  ? 195 HIS A CA  1 
ATOM 482  C C   . HIS A 1 195 ? 121.391 115.069 96.116  1.00 88.02  ? 195 HIS A C   1 
ATOM 483  O O   . HIS A 1 195 ? 120.236 114.898 96.521  1.00 85.39  ? 195 HIS A O   1 
ATOM 484  C CB  . HIS A 1 195 ? 122.147 112.693 95.784  1.00 89.45  ? 195 HIS A CB  1 
ATOM 485  C CG  . HIS A 1 195 ? 122.201 112.702 94.288  1.00 92.61  ? 195 HIS A CG  1 
ATOM 486  N ND1 . HIS A 1 195 ? 123.378 112.856 93.588  1.00 91.63  ? 195 HIS A ND1 1 
ATOM 487  C CD2 . HIS A 1 195 ? 121.226 112.567 93.358  1.00 92.84  ? 195 HIS A CD2 1 
ATOM 488  C CE1 . HIS A 1 195 ? 123.126 112.820 92.292  1.00 90.64  ? 195 HIS A CE1 1 
ATOM 489  N NE2 . HIS A 1 195 ? 121.828 112.643 92.126  1.00 90.15  ? 195 HIS A NE2 1 
ATOM 490  N N   . PHE A 1 196 ? 121.766 116.127 95.403  1.00 83.13  ? 196 PHE A N   1 
ATOM 491  C CA  . PHE A 1 196 ? 120.860 117.202 95.027  1.00 86.11  ? 196 PHE A CA  1 
ATOM 492  C C   . PHE A 1 196 ? 120.489 117.109 93.554  1.00 83.31  ? 196 PHE A C   1 
ATOM 493  O O   . PHE A 1 196 ? 121.345 116.858 92.700  1.00 81.66  ? 196 PHE A O   1 
ATOM 494  C CB  . PHE A 1 196 ? 121.487 118.571 95.303  1.00 84.39  ? 196 PHE A CB  1 
ATOM 495  C CG  . PHE A 1 196 ? 121.884 118.783 96.735  1.00 82.12  ? 196 PHE A CG  1 
ATOM 496  C CD1 . PHE A 1 196 ? 123.145 118.420 97.178  1.00 80.64  ? 196 PHE A CD1 1 
ATOM 497  C CD2 . PHE A 1 196 ? 121.002 119.355 97.635  1.00 83.18  ? 196 PHE A CD2 1 
ATOM 498  C CE1 . PHE A 1 196 ? 123.515 118.618 98.491  1.00 84.38  ? 196 PHE A CE1 1 
ATOM 499  C CE2 . PHE A 1 196 ? 121.367 119.555 98.950  1.00 85.98  ? 196 PHE A CE2 1 
ATOM 500  C CZ  . PHE A 1 196 ? 122.626 119.187 99.378  1.00 88.16  ? 196 PHE A CZ  1 
ATOM 501  N N   . LYS A 1 197 ? 119.207 117.309 93.263  1.00 70.71  ? 197 LYS A N   1 
ATOM 502  C CA  . LYS A 1 197 ? 118.714 117.441 91.895  1.00 74.39  ? 197 LYS A CA  1 
ATOM 503  C C   . LYS A 1 197 ? 118.189 118.860 91.719  1.00 75.66  ? 197 LYS A C   1 
ATOM 504  O O   . LYS A 1 197 ? 117.103 119.194 92.203  1.00 87.24  ? 197 LYS A O   1 
ATOM 505  C CB  . LYS A 1 197 ? 117.613 116.431 91.587  1.00 73.58  ? 197 LYS A CB  1 
ATOM 506  C CG  . LYS A 1 197 ? 118.017 114.975 91.542  1.00 80.85  ? 197 LYS A CG  1 
ATOM 507  C CD  . LYS A 1 197 ? 116.786 114.131 91.237  1.00 73.27  ? 197 LYS A CD  1 
ATOM 508  C CE  . LYS A 1 197 ? 117.111 112.655 91.144  1.00 72.81  ? 197 LYS A CE  1 
ATOM 509  N NZ  . LYS A 1 197 ? 115.893 111.843 90.869  1.00 73.94  ? 197 LYS A NZ  1 
ATOM 510  N N   . MET A 1 198 ? 118.960 119.694 91.029  1.00 62.91  ? 198 MET A N   1 
ATOM 511  C CA  . MET A 1 198 ? 118.582 121.076 90.775  1.00 54.20  ? 198 MET A CA  1 
ATOM 512  C C   . MET A 1 198 ? 118.051 121.176 89.353  1.00 59.49  ? 198 MET A C   1 
ATOM 513  O O   . MET A 1 198 ? 118.733 120.779 88.402  1.00 71.43  ? 198 MET A O   1 
ATOM 514  C CB  . MET A 1 198 ? 119.768 122.020 90.974  1.00 54.22  ? 198 MET A CB  1 
ATOM 515  C CG  . MET A 1 198 ? 119.432 123.488 90.768  1.00 52.99  ? 198 MET A CG  1 
ATOM 516  S SD  . MET A 1 198 ? 120.836 124.563 91.111  1.00 66.40  ? 198 MET A SD  1 
ATOM 517  C CE  . MET A 1 198 ? 122.039 123.922 89.949  1.00 67.46  ? 198 MET A CE  1 
ATOM 518  N N   . PHE A 1 199 ? 116.841 121.705 89.210  1.00 46.79  ? 199 PHE A N   1 
ATOM 519  C CA  . PHE A 1 199 ? 116.154 121.757 87.927  1.00 50.20  ? 199 PHE A CA  1 
ATOM 520  C C   . PHE A 1 199 ? 116.073 123.203 87.458  1.00 56.45  ? 199 PHE A C   1 
ATOM 521  O O   . PHE A 1 199 ? 115.541 124.061 88.170  1.00 66.67  ? 199 PHE A O   1 
ATOM 522  C CB  . PHE A 1 199 ? 114.761 121.138 88.039  1.00 46.58  ? 199 PHE A CB  1 
ATOM 523  C CG  . PHE A 1 199 ? 114.757 119.774 88.673  1.00 45.21  ? 199 PHE A CG  1 
ATOM 524  C CD1 . PHE A 1 199 ? 115.038 118.645 87.923  1.00 60.44  ? 199 PHE A CD1 1 
ATOM 525  C CD2 . PHE A 1 199 ? 114.483 119.622 90.021  1.00 54.23  ? 199 PHE A CD2 1 
ATOM 526  C CE1 . PHE A 1 199 ? 115.039 117.393 88.506  1.00 62.42  ? 199 PHE A CE1 1 
ATOM 527  C CE2 . PHE A 1 199 ? 114.484 118.373 90.608  1.00 57.08  ? 199 PHE A CE2 1 
ATOM 528  C CZ  . PHE A 1 199 ? 114.763 117.258 89.849  1.00 51.54  ? 199 PHE A CZ  1 
ATOM 529  N N   . ASP A 1 200 ? 116.599 123.467 86.266  1.00 56.79  ? 200 ASP A N   1 
ATOM 530  C CA  . ASP A 1 200 ? 116.560 124.794 85.666  1.00 57.27  ? 200 ASP A CA  1 
ATOM 531  C C   . ASP A 1 200 ? 115.511 124.790 84.562  1.00 64.22  ? 200 ASP A C   1 
ATOM 532  O O   . ASP A 1 200 ? 115.597 123.993 83.622  1.00 68.93  ? 200 ASP A O   1 
ATOM 533  C CB  . ASP A 1 200 ? 117.930 125.189 85.116  1.00 59.08  ? 200 ASP A CB  1 
ATOM 534  C CG  . ASP A 1 200 ? 117.976 126.630 84.642  1.00 67.29  ? 200 ASP A CG  1 
ATOM 535  O OD1 . ASP A 1 200 ? 117.010 127.378 84.903  1.00 68.76  ? 200 ASP A OD1 1 
ATOM 536  O OD2 . ASP A 1 200 ? 118.983 127.017 84.012  1.00 71.92  ? 200 ASP A OD2 1 
ATOM 537  N N   . VAL A 1 201 ? 114.527 125.677 84.681  1.00 69.12  ? 201 VAL A N   1 
ATOM 538  C CA  . VAL A 1 201 ? 113.425 125.741 83.729  1.00 70.58  ? 201 VAL A CA  1 
ATOM 539  C C   . VAL A 1 201 ? 113.432 127.085 83.016  1.00 72.27  ? 201 VAL A C   1 
ATOM 540  O O   . VAL A 1 201 ? 112.375 127.609 82.646  1.00 74.66  ? 201 VAL A O   1 
ATOM 541  C CB  . VAL A 1 201 ? 112.081 125.493 84.434  1.00 64.62  ? 201 VAL A CB  1 
ATOM 542  C CG1 . VAL A 1 201 ? 111.890 124.007 84.698  1.00 58.95  ? 201 VAL A CG1 1 
ATOM 543  C CG2 . VAL A 1 201 ? 112.023 126.274 85.737  1.00 64.50  ? 201 VAL A CG2 1 
ATOM 544  N N   . GLY A 1 202 ? 114.623 127.658 82.825  1.00 64.30  ? 202 GLY A N   1 
ATOM 545  C CA  . GLY A 1 202 ? 114.714 128.939 82.145  1.00 64.30  ? 202 GLY A CA  1 
ATOM 546  C C   . GLY A 1 202 ? 114.334 128.875 80.680  1.00 64.00  ? 202 GLY A C   1 
ATOM 547  O O   . GLY A 1 202 ? 113.913 129.882 80.102  1.00 58.16  ? 202 GLY A O   1 
ATOM 548  N N   . ALA A 1 203 ? 114.472 127.703 80.060  1.00 73.78  ? 203 ALA A N   1 
ATOM 549  C CA  . ALA A 1 203 ? 114.116 127.533 78.657  1.00 76.60  ? 203 ALA A CA  1 
ATOM 550  C C   . ALA A 1 203 ? 112.620 127.356 78.435  1.00 76.28  ? 203 ALA A C   1 
ATOM 551  O O   . ALA A 1 203 ? 112.163 127.475 77.293  1.00 75.95  ? 203 ALA A O   1 
ATOM 552  C CB  . ALA A 1 203 ? 114.867 126.337 78.067  1.00 70.30  ? 203 ALA A CB  1 
ATOM 553  N N   . GLN A 1 204 ? 111.853 127.072 79.484  1.00 77.90  ? 204 GLN A N   1 
ATOM 554  C CA  . GLN A 1 204 ? 110.404 126.918 79.365  1.00 76.34  ? 204 GLN A CA  1 
ATOM 555  C C   . GLN A 1 204 ? 109.777 128.298 79.211  1.00 80.85  ? 204 GLN A C   1 
ATOM 556  O O   . GLN A 1 204 ? 109.525 128.993 80.198  1.00 79.57  ? 204 GLN A O   1 
ATOM 557  C CB  . GLN A 1 204 ? 109.842 126.187 80.578  1.00 76.15  ? 204 GLN A CB  1 
ATOM 558  C CG  . GLN A 1 204 ? 110.390 124.781 80.769  1.00 74.18  ? 204 GLN A CG  1 
ATOM 559  C CD  . GLN A 1 204 ? 109.926 123.821 79.693  1.00 75.27  ? 204 GLN A CD  1 
ATOM 560  O OE1 . GLN A 1 204 ? 108.832 123.962 79.147  1.00 79.35  ? 204 GLN A OE1 1 
ATOM 561  N NE2 . GLN A 1 204 ? 110.761 122.836 79.379  1.00 73.64  ? 204 GLN A NE2 1 
ATOM 562  N N   . ARG A 1 205 ? 109.524 128.702 77.967  1.00 88.38  ? 205 ARG A N   1 
ATOM 563  C CA  . ARG A 1 205 ? 108.896 129.988 77.698  1.00 88.46  ? 205 ARG A CA  1 
ATOM 564  C C   . ARG A 1 205 ? 107.378 129.935 77.800  1.00 91.54  ? 205 ARG A C   1 
ATOM 565  O O   . ARG A 1 205 ? 106.724 130.970 77.629  1.00 92.09  ? 205 ARG A O   1 
ATOM 566  C CB  . ARG A 1 205 ? 109.301 130.492 76.311  1.00 83.43  ? 205 ARG A CB  1 
ATOM 567  N N   . SER A 1 206 ? 106.807 128.765 78.072  1.00 89.30  ? 206 SER A N   1 
ATOM 568  C CA  . SER A 1 206 ? 105.366 128.619 78.189  1.00 82.21  ? 206 SER A CA  1 
ATOM 569  C C   . SER A 1 206 ? 104.868 129.282 79.473  1.00 81.82  ? 206 SER A C   1 
ATOM 570  O O   . SER A 1 206 ? 105.636 129.841 80.262  1.00 83.65  ? 206 SER A O   1 
ATOM 571  C CB  . SER A 1 206 ? 104.982 127.143 78.149  1.00 80.83  ? 206 SER A CB  1 
ATOM 572  O OG  . SER A 1 206 ? 105.399 126.542 76.935  1.00 87.38  ? 206 SER A OG  1 
ATOM 573  N N   . GLU A 1 207 ? 103.555 129.216 79.682  1.00 91.43  ? 207 GLU A N   1 
ATOM 574  C CA  . GLU A 1 207 ? 102.960 129.776 80.887  1.00 96.32  ? 207 GLU A CA  1 
ATOM 575  C C   . GLU A 1 207 ? 103.431 128.996 82.108  1.00 88.25  ? 207 GLU A C   1 
ATOM 576  O O   . GLU A 1 207 ? 103.315 127.768 82.157  1.00 88.06  ? 207 GLU A O   1 
ATOM 577  C CB  . GLU A 1 207 ? 101.437 129.748 80.785  1.00 94.03  ? 207 GLU A CB  1 
ATOM 578  C CG  . GLU A 1 207 ? 100.875 130.686 79.728  1.00 91.98  ? 207 GLU A CG  1 
ATOM 579  C CD  . GLU A 1 207 ? 99.368  130.825 79.808  1.00 91.17  ? 207 GLU A CD  1 
ATOM 580  O OE1 . GLU A 1 207 ? 98.762  130.222 80.718  1.00 91.34  ? 207 GLU A OE1 1 
ATOM 581  O OE2 . GLU A 1 207 ? 98.790  131.536 78.960  1.00 93.17  ? 207 GLU A OE2 1 
ATOM 582  N N   . ARG A 1 208 ? 103.975 129.717 83.092  1.00 74.28  ? 208 ARG A N   1 
ATOM 583  C CA  . ARG A 1 208 ? 104.570 129.062 84.253  1.00 74.52  ? 208 ARG A CA  1 
ATOM 584  C C   . ARG A 1 208 ? 103.528 128.298 85.062  1.00 76.03  ? 208 ARG A C   1 
ATOM 585  O O   . ARG A 1 208 ? 103.805 127.203 85.565  1.00 81.75  ? 208 ARG A O   1 
ATOM 586  C CB  . ARG A 1 208 ? 105.283 130.096 85.125  1.00 79.71  ? 208 ARG A CB  1 
ATOM 587  C CG  . ARG A 1 208 ? 106.203 129.498 86.178  1.00 77.20  ? 208 ARG A CG  1 
ATOM 588  C CD  . ARG A 1 208 ? 106.899 130.584 86.984  1.00 81.48  ? 208 ARG A CD  1 
ATOM 589  N NE  . ARG A 1 208 ? 107.561 131.561 86.127  1.00 84.48  ? 208 ARG A NE  1 
ATOM 590  C CZ  . ARG A 1 208 ? 108.801 131.443 85.672  1.00 82.42  ? 208 ARG A CZ  1 
ATOM 591  N NH1 . ARG A 1 208 ? 109.551 130.395 85.971  1.00 81.86  ? 208 ARG A NH1 1 
ATOM 592  N NH2 . ARG A 1 208 ? 109.301 132.400 84.896  1.00 76.35  ? 208 ARG A NH2 1 
ATOM 593  N N   . LYS A 1 209 ? 102.322 128.858 85.196  1.00 74.90  ? 209 LYS A N   1 
ATOM 594  C CA  . LYS A 1 209 ? 101.301 128.265 86.055  1.00 81.64  ? 209 LYS A CA  1 
ATOM 595  C C   . LYS A 1 209 ? 100.877 126.871 85.604  1.00 81.95  ? 209 LYS A C   1 
ATOM 596  O O   . LYS A 1 209 ? 100.281 126.133 86.396  1.00 78.14  ? 209 LYS A O   1 
ATOM 597  C CB  . LYS A 1 209 ? 100.080 129.184 86.139  1.00 80.25  ? 209 LYS A CB  1 
ATOM 598  C CG  . LYS A 1 209 ? 99.502  129.603 84.801  1.00 80.44  ? 209 LYS A CG  1 
ATOM 599  C CD  . LYS A 1 209 ? 98.271  130.472 85.005  1.00 79.49  ? 209 LYS A CD  1 
ATOM 600  C CE  . LYS A 1 209 ? 97.682  130.930 83.684  1.00 81.41  ? 209 LYS A CE  1 
ATOM 601  N NZ  . LYS A 1 209 ? 96.477  131.780 83.887  1.00 80.31  ? 209 LYS A NZ  1 
ATOM 602  N N   . LYS A 1 210 ? 101.168 126.491 84.359  1.00 81.00  ? 210 LYS A N   1 
ATOM 603  C CA  . LYS A 1 210 ? 100.674 125.220 83.836  1.00 73.90  ? 210 LYS A CA  1 
ATOM 604  C C   . LYS A 1 210 ? 101.522 124.053 84.326  1.00 69.75  ? 210 LYS A C   1 
ATOM 605  O O   . LYS A 1 210 ? 100.987 123.028 84.761  1.00 72.91  ? 210 LYS A O   1 
ATOM 606  C CB  . LYS A 1 210 ? 100.641 125.253 82.307  1.00 72.71  ? 210 LYS A CB  1 
ATOM 607  C CG  . LYS A 1 210 ? 99.759  126.345 81.736  1.00 78.67  ? 210 LYS A CG  1 
ATOM 608  C CD  . LYS A 1 210 ? 98.351  126.227 82.291  1.00 76.89  ? 210 LYS A CD  1 
ATOM 609  C CE  . LYS A 1 210 ? 97.677  124.940 81.838  1.00 74.21  ? 210 LYS A CE  1 
ATOM 610  N NZ  . LYS A 1 210 ? 96.290  124.831 82.369  1.00 76.93  ? 210 LYS A NZ  1 
ATOM 611  N N   . TRP A 1 211 ? 102.841 124.188 84.255  1.00 62.76  ? 211 TRP A N   1 
ATOM 612  C CA  . TRP A 1 211 ? 103.760 123.111 84.589  1.00 62.23  ? 211 TRP A CA  1 
ATOM 613  C C   . TRP A 1 211 ? 104.406 123.286 85.957  1.00 69.39  ? 211 TRP A C   1 
ATOM 614  O O   . TRP A 1 211 ? 105.221 122.447 86.353  1.00 71.27  ? 211 TRP A O   1 
ATOM 615  C CB  . TRP A 1 211 ? 104.843 122.997 83.513  1.00 57.55  ? 211 TRP A CB  1 
ATOM 616  C CG  . TRP A 1 211 ? 105.511 124.298 83.210  1.00 64.06  ? 211 TRP A CG  1 
ATOM 617  C CD1 . TRP A 1 211 ? 105.173 125.182 82.227  1.00 74.93  ? 211 TRP A CD1 1 
ATOM 618  C CD2 . TRP A 1 211 ? 106.620 124.876 83.906  1.00 68.14  ? 211 TRP A CD2 1 
ATOM 619  N NE1 . TRP A 1 211 ? 106.011 126.271 82.261  1.00 77.55  ? 211 TRP A NE1 1 
ATOM 620  C CE2 . TRP A 1 211 ? 106.907 126.107 83.284  1.00 72.89  ? 211 TRP A CE2 1 
ATOM 621  C CE3 . TRP A 1 211 ? 107.401 124.470 84.991  1.00 68.44  ? 211 TRP A CE3 1 
ATOM 622  C CZ2 . TRP A 1 211 ? 107.941 126.935 83.711  1.00 69.90  ? 211 TRP A CZ2 1 
ATOM 623  C CZ3 . TRP A 1 211 ? 108.425 125.292 85.414  1.00 67.45  ? 211 TRP A CZ3 1 
ATOM 624  C CH2 . TRP A 1 211 ? 108.686 126.511 84.776  1.00 66.54  ? 211 TRP A CH2 1 
ATOM 625  N N   . ILE A 1 212 ? 104.066 124.352 86.687  1.00 69.93  ? 212 ILE A N   1 
ATOM 626  C CA  . ILE A 1 212 ? 104.712 124.603 87.972  1.00 64.71  ? 212 ILE A CA  1 
ATOM 627  C C   . ILE A 1 212 ? 104.274 123.574 89.007  1.00 71.21  ? 212 ILE A C   1 
ATOM 628  O O   . ILE A 1 212 ? 105.018 123.276 89.949  1.00 76.16  ? 212 ILE A O   1 
ATOM 629  C CB  . ILE A 1 212 ? 104.425 126.042 88.446  1.00 62.88  ? 212 ILE A CB  1 
ATOM 630  C CG1 . ILE A 1 212 ? 105.245 126.378 89.695  1.00 67.78  ? 212 ILE A CG1 1 
ATOM 631  C CG2 . ILE A 1 212 ? 102.938 126.242 88.708  1.00 66.54  ? 212 ILE A CG2 1 
ATOM 632  C CD1 . ILE A 1 212 ? 106.740 126.280 89.486  1.00 65.97  ? 212 ILE A CD1 1 
ATOM 633  N N   . HIS A 1 213 ? 103.074 123.005 88.853  1.00 69.12  ? 213 HIS A N   1 
ATOM 634  C CA  . HIS A 1 213 ? 102.611 122.007 89.808  1.00 60.77  ? 213 HIS A CA  1 
ATOM 635  C C   . HIS A 1 213 ? 103.391 120.705 89.705  1.00 47.45  ? 213 HIS A C   1 
ATOM 636  O O   . HIS A 1 213 ? 103.328 119.885 90.628  1.00 46.95  ? 213 HIS A O   1 
ATOM 637  C CB  . HIS A 1 213 ? 101.116 121.740 89.615  1.00 62.09  ? 213 HIS A CB  1 
ATOM 638  C CG  . HIS A 1 213 ? 100.732 121.417 88.204  1.00 56.29  ? 213 HIS A CG  1 
ATOM 639  N ND1 . HIS A 1 213 ? 101.253 120.344 87.514  1.00 58.02  ? 213 HIS A ND1 1 
ATOM 640  C CD2 . HIS A 1 213 ? 99.866  122.023 87.357  1.00 58.05  ? 213 HIS A CD2 1 
ATOM 641  C CE1 . HIS A 1 213 ? 100.730 120.307 86.301  1.00 61.35  ? 213 HIS A CE1 1 
ATOM 642  N NE2 . HIS A 1 213 ? 99.886  121.315 86.180  1.00 61.87  ? 213 HIS A NE2 1 
ATOM 643  N N   . CYS A 1 214 ? 104.111 120.489 88.601  1.00 47.11  ? 214 CYS A N   1 
ATOM 644  C CA  . CYS A 1 214 ? 104.950 119.303 88.481  1.00 57.29  ? 214 CYS A CA  1 
ATOM 645  C C   . CYS A 1 214 ? 106.068 119.284 89.513  1.00 60.43  ? 214 CYS A C   1 
ATOM 646  O O   . CYS A 1 214 ? 106.626 118.216 89.787  1.00 62.87  ? 214 CYS A O   1 
ATOM 647  C CB  . CYS A 1 214 ? 105.538 119.214 87.072  1.00 57.49  ? 214 CYS A CB  1 
ATOM 648  S SG  . CYS A 1 214 ? 104.306 119.033 85.760  1.00 61.30  ? 214 CYS A SG  1 
ATOM 649  N N   . PHE A 1 215 ? 106.398 120.433 90.101  1.00 51.37  ? 215 PHE A N   1 
ATOM 650  C CA  . PHE A 1 215 ? 107.433 120.526 91.120  1.00 44.72  ? 215 PHE A CA  1 
ATOM 651  C C   . PHE A 1 215 ? 106.868 120.599 92.532  1.00 48.36  ? 215 PHE A C   1 
ATOM 652  O O   . PHE A 1 215 ? 107.616 120.884 93.472  1.00 46.16  ? 215 PHE A O   1 
ATOM 653  C CB  . PHE A 1 215 ? 108.324 121.742 90.855  1.00 40.04  ? 215 PHE A CB  1 
ATOM 654  C CG  . PHE A 1 215 ? 109.166 121.621 89.618  1.00 43.61  ? 215 PHE A CG  1 
ATOM 655  C CD1 . PHE A 1 215 ? 110.427 121.052 89.675  1.00 51.95  ? 215 PHE A CD1 1 
ATOM 656  C CD2 . PHE A 1 215 ? 108.700 122.083 88.399  1.00 45.79  ? 215 PHE A CD2 1 
ATOM 657  C CE1 . PHE A 1 215 ? 111.206 120.942 88.540  1.00 55.92  ? 215 PHE A CE1 1 
ATOM 658  C CE2 . PHE A 1 215 ? 109.474 121.976 87.260  1.00 58.61  ? 215 PHE A CE2 1 
ATOM 659  C CZ  . PHE A 1 215 ? 110.729 121.404 87.332  1.00 57.95  ? 215 PHE A CZ  1 
ATOM 660  N N   . GLU A 1 216 ? 105.570 120.358 92.704  1.00 61.67  ? 216 GLU A N   1 
ATOM 661  C CA  . GLU A 1 216 ? 105.004 120.271 94.043  1.00 59.88  ? 216 GLU A CA  1 
ATOM 662  C C   . GLU A 1 216 ? 105.589 119.070 94.772  1.00 53.79  ? 216 GLU A C   1 
ATOM 663  O O   . GLU A 1 216 ? 105.370 117.923 94.372  1.00 60.87  ? 216 GLU A O   1 
ATOM 664  C CB  . GLU A 1 216 ? 103.482 120.167 93.966  1.00 63.56  ? 216 GLU A CB  1 
ATOM 665  C CG  . GLU A 1 216 ? 102.805 120.013 95.316  1.00 61.67  ? 216 GLU A CG  1 
ATOM 666  C CD  . GLU A 1 216 ? 101.325 119.707 95.195  1.00 66.46  ? 216 GLU A CD  1 
ATOM 667  O OE1 . GLU A 1 216 ? 100.861 119.441 94.067  1.00 66.69  ? 216 GLU A OE1 1 
ATOM 668  O OE2 . GLU A 1 216 ? 100.626 119.730 96.230  1.00 68.30  ? 216 GLU A OE2 1 
ATOM 669  N N   . GLY A 1 217 ? 106.331 119.333 95.843  1.00 41.26  ? 217 GLY A N   1 
ATOM 670  C CA  . GLY A 1 217 ? 107.050 118.289 96.550  1.00 57.05  ? 217 GLY A CA  1 
ATOM 671  C C   . GLY A 1 217 ? 108.558 118.434 96.534  1.00 49.39  ? 217 GLY A C   1 
ATOM 672  O O   . GLY A 1 217 ? 109.243 117.627 97.177  1.00 50.24  ? 217 GLY A O   1 
ATOM 673  N N   . VAL A 1 218 ? 109.118 119.421 95.830  1.00 35.18  ? 218 VAL A N   1 
ATOM 674  C CA  . VAL A 1 218 ? 110.547 119.680 95.934  1.00 39.94  ? 218 VAL A CA  1 
ATOM 675  C C   . VAL A 1 218 ? 110.894 120.136 97.349  1.00 38.38  ? 218 VAL A C   1 
ATOM 676  O O   . VAL A 1 218 ? 110.076 120.736 98.058  1.00 33.43  ? 218 VAL A O   1 
ATOM 677  C CB  . VAL A 1 218 ? 110.994 120.724 94.897  1.00 43.45  ? 218 VAL A CB  1 
ATOM 678  C CG1 . VAL A 1 218 ? 110.779 120.199 93.486  1.00 47.36  ? 218 VAL A CG1 1 
ATOM 679  C CG2 . VAL A 1 218 ? 110.250 122.032 95.104  1.00 37.57  ? 218 VAL A CG2 1 
ATOM 680  N N   . THR A 1 219 ? 112.126 119.832 97.765  1.00 44.92  ? 219 THR A N   1 
ATOM 681  C CA  . THR A 1 219 ? 112.562 120.166 99.117  1.00 41.33  ? 219 THR A CA  1 
ATOM 682  C C   . THR A 1 219 ? 112.588 121.674 99.337  1.00 46.43  ? 219 THR A C   1 
ATOM 683  O O   . THR A 1 219 ? 112.081 122.176 100.347 1.00 60.53  ? 219 THR A O   1 
ATOM 684  C CB  . THR A 1 219 ? 113.942 119.560 99.379  1.00 43.43  ? 219 THR A CB  1 
ATOM 685  O OG1 . THR A 1 219 ? 113.868 118.134 99.266  1.00 50.14  ? 219 THR A OG1 1 
ATOM 686  C CG2 . THR A 1 219 ? 114.439 119.924 100.767 1.00 51.11  ? 219 THR A CG2 1 
ATOM 687  N N   . ALA A 1 220 ? 113.166 122.415 98.397  1.00 38.87  ? 220 ALA A N   1 
ATOM 688  C CA  . ALA A 1 220 ? 113.297 123.856 98.539  1.00 40.29  ? 220 ALA A CA  1 
ATOM 689  C C   . ALA A 1 220 ? 113.397 124.483 97.157  1.00 41.52  ? 220 ALA A C   1 
ATOM 690  O O   . ALA A 1 220 ? 113.631 123.802 96.156  1.00 53.02  ? 220 ALA A O   1 
ATOM 691  C CB  . ALA A 1 220 ? 114.509 124.228 99.399  1.00 49.02  ? 220 ALA A CB  1 
ATOM 692  N N   . ILE A 1 221 ? 113.214 125.799 97.113  1.00 35.08  ? 221 ILE A N   1 
ATOM 693  C CA  . ILE A 1 221 ? 113.307 126.575 95.883  1.00 33.05  ? 221 ILE A CA  1 
ATOM 694  C C   . ILE A 1 221 ? 114.459 127.558 96.021  1.00 41.64  ? 221 ILE A C   1 
ATOM 695  O O   . ILE A 1 221 ? 114.504 128.337 96.981  1.00 51.49  ? 221 ILE A O   1 
ATOM 696  C CB  . ILE A 1 221 ? 111.995 127.319 95.581  1.00 40.68  ? 221 ILE A CB  1 
ATOM 697  C CG1 . ILE A 1 221 ? 110.848 126.325 95.400  1.00 35.65  ? 221 ILE A CG1 1 
ATOM 698  C CG2 . ILE A 1 221 ? 112.148 128.193 94.348  1.00 39.05  ? 221 ILE A CG2 1 
ATOM 699  C CD1 . ILE A 1 221 ? 109.521 126.983 95.134  1.00 40.73  ? 221 ILE A CD1 1 
ATOM 700  N N   . ILE A 1 222 ? 115.384 127.524 95.068  1.00 26.30  ? 222 ILE A N   1 
ATOM 701  C CA  . ILE A 1 222 ? 116.495 128.468 95.027  1.00 36.64  ? 222 ILE A CA  1 
ATOM 702  C C   . ILE A 1 222 ? 116.099 129.621 94.115  1.00 34.91  ? 222 ILE A C   1 
ATOM 703  O O   . ILE A 1 222 ? 115.907 129.433 92.909  1.00 49.05  ? 222 ILE A O   1 
ATOM 704  C CB  . ILE A 1 222 ? 117.787 127.795 94.540  1.00 38.00  ? 222 ILE A CB  1 
ATOM 705  C CG1 . ILE A 1 222 ? 118.134 126.598 95.426  1.00 33.64  ? 222 ILE A CG1 1 
ATOM 706  C CG2 . ILE A 1 222 ? 118.930 128.795 94.522  1.00 33.00  ? 222 ILE A CG2 1 
ATOM 707  C CD1 . ILE A 1 222 ? 119.422 125.904 95.043  1.00 30.18  ? 222 ILE A CD1 1 
ATOM 708  N N   . PHE A 1 223 ? 115.978 130.815 94.689  1.00 45.75  ? 223 PHE A N   1 
ATOM 709  C CA  . PHE A 1 223 ? 115.551 132.006 93.966  1.00 48.96  ? 223 PHE A CA  1 
ATOM 710  C C   . PHE A 1 223 ? 116.715 132.984 93.897  1.00 55.17  ? 223 PHE A C   1 
ATOM 711  O O   . PHE A 1 223 ? 117.282 133.353 94.932  1.00 65.93  ? 223 PHE A O   1 
ATOM 712  C CB  . PHE A 1 223 ? 114.341 132.650 94.643  1.00 54.46  ? 223 PHE A CB  1 
ATOM 713  C CG  . PHE A 1 223 ? 113.515 133.502 93.724  1.00 56.03  ? 223 PHE A CG  1 
ATOM 714  C CD1 . PHE A 1 223 ? 113.880 134.809 93.451  1.00 61.39  ? 223 PHE A CD1 1 
ATOM 715  C CD2 . PHE A 1 223 ? 112.369 132.996 93.134  1.00 59.55  ? 223 PHE A CD2 1 
ATOM 716  C CE1 . PHE A 1 223 ? 113.120 135.594 92.605  1.00 61.24  ? 223 PHE A CE1 1 
ATOM 717  C CE2 . PHE A 1 223 ? 111.605 133.776 92.288  1.00 63.25  ? 223 PHE A CE2 1 
ATOM 718  C CZ  . PHE A 1 223 ? 111.981 135.076 92.024  1.00 59.90  ? 223 PHE A CZ  1 
ATOM 719  N N   . CYS A 1 224 ? 117.071 133.399 92.685  1.00 72.87  ? 224 CYS A N   1 
ATOM 720  C CA  . CYS A 1 224 ? 118.197 134.294 92.457  1.00 80.04  ? 224 CYS A CA  1 
ATOM 721  C C   . CYS A 1 224 ? 117.680 135.689 92.132  1.00 82.23  ? 224 CYS A C   1 
ATOM 722  O O   . CYS A 1 224 ? 116.881 135.859 91.205  1.00 87.45  ? 224 CYS A O   1 
ATOM 723  C CB  . CYS A 1 224 ? 119.078 133.776 91.319  1.00 83.71  ? 224 CYS A CB  1 
ATOM 724  S SG  . CYS A 1 224 ? 119.885 132.193 91.657  1.00 85.58  ? 224 CYS A SG  1 
ATOM 725  N N   . VAL A 1 225 ? 118.140 136.681 92.893  1.00 88.37  ? 225 VAL A N   1 
ATOM 726  C CA  . VAL A 1 225 ? 117.782 138.080 92.684  1.00 90.40  ? 225 VAL A CA  1 
ATOM 727  C C   . VAL A 1 225 ? 119.062 138.891 92.550  1.00 92.15  ? 225 VAL A C   1 
ATOM 728  O O   . VAL A 1 225 ? 119.985 138.739 93.358  1.00 89.53  ? 225 VAL A O   1 
ATOM 729  C CB  . VAL A 1 225 ? 116.916 138.628 93.835  1.00 92.36  ? 225 VAL A CB  1 
ATOM 730  C CG1 . VAL A 1 225 ? 116.637 140.111 93.632  1.00 94.61  ? 225 VAL A CG1 1 
ATOM 731  C CG2 . VAL A 1 225 ? 115.618 137.849 93.943  1.00 92.75  ? 225 VAL A CG2 1 
ATOM 732  N N   . ALA A 1 226 ? 119.119 139.748 91.533  1.00 116.61 ? 226 ALA A N   1 
ATOM 733  C CA  . ALA A 1 226 ? 120.276 140.603 91.305  1.00 118.31 ? 226 ALA A CA  1 
ATOM 734  C C   . ALA A 1 226 ? 120.097 141.906 92.077  1.00 119.84 ? 226 ALA A C   1 
ATOM 735  O O   . ALA A 1 226 ? 119.180 142.682 91.790  1.00 118.99 ? 226 ALA A O   1 
ATOM 736  C CB  . ALA A 1 226 ? 120.461 140.878 89.814  1.00 116.49 ? 226 ALA A CB  1 
ATOM 737  N N   . LEU A 1 227 ? 120.970 142.137 93.061  1.00 123.61 ? 227 LEU A N   1 
ATOM 738  C CA  . LEU A 1 227 ? 120.899 143.368 93.842  1.00 122.83 ? 227 LEU A CA  1 
ATOM 739  C C   . LEU A 1 227 ? 121.192 144.593 92.984  1.00 127.68 ? 227 LEU A C   1 
ATOM 740  O O   . LEU A 1 227 ? 120.561 145.643 93.152  1.00 128.84 ? 227 LEU A O   1 
ATOM 741  C CB  . LEU A 1 227 ? 121.866 143.297 95.023  1.00 123.60 ? 227 LEU A CB  1 
ATOM 742  C CG  . LEU A 1 227 ? 121.490 142.317 96.134  1.00 123.53 ? 227 LEU A CG  1 
ATOM 743  C CD1 . LEU A 1 227 ? 122.542 142.315 97.232  1.00 123.40 ? 227 LEU A CD1 1 
ATOM 744  C CD2 . LEU A 1 227 ? 120.123 142.669 96.698  1.00 125.36 ? 227 LEU A CD2 1 
ATOM 745  N N   . SER A 1 228 ? 122.148 144.477 92.059  1.00 136.94 ? 228 SER A N   1 
ATOM 746  C CA  . SER A 1 228 ? 122.531 145.611 91.225  1.00 135.38 ? 228 SER A CA  1 
ATOM 747  C C   . SER A 1 228 ? 121.425 146.040 90.271  1.00 133.99 ? 228 SER A C   1 
ATOM 748  O O   . SER A 1 228 ? 121.486 147.152 89.734  1.00 134.23 ? 228 SER A O   1 
ATOM 749  C CB  . SER A 1 228 ? 123.794 145.278 90.431  1.00 134.55 ? 228 SER A CB  1 
ATOM 750  O OG  . SER A 1 228 ? 123.541 144.269 89.471  1.00 133.81 ? 228 SER A OG  1 
ATOM 751  N N   . ASP A 1 229 ? 120.422 145.197 90.046  1.00 137.86 ? 229 ASP A N   1 
ATOM 752  C CA  . ASP A 1 229 ? 119.336 145.524 89.123  1.00 138.62 ? 229 ASP A CA  1 
ATOM 753  C C   . ASP A 1 229 ? 118.186 146.225 89.839  1.00 139.89 ? 229 ASP A C   1 
ATOM 754  O O   . ASP A 1 229 ? 117.026 145.825 89.745  1.00 138.72 ? 229 ASP A O   1 
ATOM 755  C CB  . ASP A 1 229 ? 118.855 144.259 88.421  1.00 139.28 ? 229 ASP A CB  1 
ATOM 756  C CG  . ASP A 1 229 ? 119.935 143.615 87.576  1.00 140.92 ? 229 ASP A CG  1 
ATOM 757  O OD1 . ASP A 1 229 ? 121.068 144.141 87.554  1.00 140.65 ? 229 ASP A OD1 1 
ATOM 758  O OD2 . ASP A 1 229 ? 119.652 142.583 86.932  1.00 140.98 ? 229 ASP A OD2 1 
ATOM 759  N N   . TYR A 1 230 ? 118.512 147.292 90.566  1.00 146.46 ? 230 TYR A N   1 
ATOM 760  C CA  . TYR A 1 230 ? 117.524 148.118 91.248  1.00 145.19 ? 230 TYR A CA  1 
ATOM 761  C C   . TYR A 1 230 ? 117.304 149.461 90.572  1.00 145.47 ? 230 TYR A C   1 
ATOM 762  O O   . TYR A 1 230 ? 116.180 149.967 90.567  1.00 145.15 ? 230 TYR A O   1 
ATOM 763  C CB  . TYR A 1 230 ? 117.941 148.350 92.706  1.00 143.68 ? 230 TYR A CB  1 
ATOM 764  C CG  . TYR A 1 230 ? 119.137 149.261 92.867  1.00 143.83 ? 230 TYR A CG  1 
ATOM 765  C CD1 . TYR A 1 230 ? 120.428 148.784 92.686  1.00 142.68 ? 230 TYR A CD1 1 
ATOM 766  C CD2 . TYR A 1 230 ? 118.975 150.599 93.202  1.00 145.82 ? 230 TYR A CD2 1 
ATOM 767  C CE1 . TYR A 1 230 ? 121.523 149.613 92.832  1.00 144.69 ? 230 TYR A CE1 1 
ATOM 768  C CE2 . TYR A 1 230 ? 120.063 151.436 93.349  1.00 146.14 ? 230 TYR A CE2 1 
ATOM 769  C CZ  . TYR A 1 230 ? 121.335 150.938 93.164  1.00 146.83 ? 230 TYR A CZ  1 
ATOM 770  O OH  . TYR A 1 230 ? 122.420 151.769 93.311  1.00 146.87 ? 230 TYR A OH  1 
ATOM 771  N N   . ASP A 1 231 ? 118.354 150.061 90.013  1.00 147.66 ? 231 ASP A N   1 
ATOM 772  C CA  . ASP A 1 231 ? 118.225 151.298 89.257  1.00 147.07 ? 231 ASP A CA  1 
ATOM 773  C C   . ASP A 1 231 ? 118.007 151.058 87.770  1.00 146.37 ? 231 ASP A C   1 
ATOM 774  O O   . ASP A 1 231 ? 117.748 152.017 87.034  1.00 145.72 ? 231 ASP A O   1 
ATOM 775  C CB  . ASP A 1 231 ? 119.468 152.173 89.457  1.00 145.27 ? 231 ASP A CB  1 
ATOM 776  C CG  . ASP A 1 231 ? 120.724 151.540 88.896  1.00 146.14 ? 231 ASP A CG  1 
ATOM 777  O OD1 . ASP A 1 231 ? 120.839 150.297 88.947  1.00 147.27 ? 231 ASP A OD1 1 
ATOM 778  O OD2 . ASP A 1 231 ? 121.597 152.284 88.404  1.00 146.33 ? 231 ASP A OD2 1 
ATOM 779  N N   . LEU A 1 232 ? 118.103 149.813 87.316  1.00 144.10 ? 232 LEU A N   1 
ATOM 780  C CA  . LEU A 1 232 ? 117.926 149.471 85.915  1.00 143.99 ? 232 LEU A CA  1 
ATOM 781  C C   . LEU A 1 232 ? 116.462 149.164 85.609  1.00 146.25 ? 232 LEU A C   1 
ATOM 782  O O   . LEU A 1 232 ? 115.638 148.956 86.502  1.00 145.54 ? 232 LEU A O   1 
ATOM 783  C CB  . LEU A 1 232 ? 118.808 148.279 85.542  1.00 143.86 ? 232 LEU A CB  1 
ATOM 784  C CG  . LEU A 1 232 ? 120.309 148.436 85.796  1.00 143.63 ? 232 LEU A CG  1 
ATOM 785  C CD1 . LEU A 1 232 ? 121.061 147.192 85.350  1.00 144.26 ? 232 LEU A CD1 1 
ATOM 786  C CD2 . LEU A 1 232 ? 120.846 149.673 85.094  1.00 144.14 ? 232 LEU A CD2 1 
ATOM 787  N N   . VAL A 1 233 ? 116.146 149.140 84.316  1.00 156.37 ? 233 VAL A N   1 
ATOM 788  C CA  . VAL A 1 233 ? 114.804 148.857 83.831  1.00 155.78 ? 233 VAL A CA  1 
ATOM 789  C C   . VAL A 1 233 ? 114.874 147.669 82.881  1.00 156.40 ? 233 VAL A C   1 
ATOM 790  O O   . VAL A 1 233 ? 115.933 147.327 82.349  1.00 156.33 ? 233 VAL A O   1 
ATOM 791  C CB  . VAL A 1 233 ? 114.162 150.075 83.134  1.00 155.21 ? 233 VAL A CB  1 
ATOM 792  C CG1 . VAL A 1 233 ? 114.020 151.233 84.110  1.00 153.70 ? 233 VAL A CG1 1 
ATOM 793  C CG2 . VAL A 1 233 ? 114.984 150.487 81.922  1.00 155.31 ? 233 VAL A CG2 1 
ATOM 794  N N   . LEU A 1 234 ? 113.723 147.032 82.681  1.00 162.18 ? 234 LEU A N   1 
ATOM 795  C CA  . LEU A 1 234 ? 113.657 145.862 81.816  1.00 163.07 ? 234 LEU A CA  1 
ATOM 796  C C   . LEU A 1 234 ? 113.989 146.242 80.378  1.00 163.73 ? 234 LEU A C   1 
ATOM 797  O O   . LEU A 1 234 ? 113.670 147.338 79.909  1.00 163.39 ? 234 LEU A O   1 
ATOM 798  C CB  . LEU A 1 234 ? 112.269 145.224 81.884  1.00 161.84 ? 234 LEU A CB  1 
ATOM 799  C CG  . LEU A 1 234 ? 111.802 144.732 83.256  1.00 161.02 ? 234 LEU A CG  1 
ATOM 800  C CD1 . LEU A 1 234 ? 110.415 144.118 83.163  1.00 162.34 ? 234 LEU A CD1 1 
ATOM 801  C CD2 . LEU A 1 234 ? 112.794 143.736 83.835  1.00 160.14 ? 234 LEU A CD2 1 
ATOM 802  N N   . ALA A 1 235 ? 114.652 145.320 79.677  1.00 168.13 ? 235 ALA A N   1 
ATOM 803  C CA  . ALA A 1 235 ? 115.032 145.575 78.291  1.00 167.42 ? 235 ALA A CA  1 
ATOM 804  C C   . ALA A 1 235 ? 113.808 145.717 77.395  1.00 168.96 ? 235 ALA A C   1 
ATOM 805  O O   . ALA A 1 235 ? 113.787 146.564 76.494  1.00 168.81 ? 235 ALA A O   1 
ATOM 806  C CB  . ALA A 1 235 ? 115.944 144.458 77.783  1.00 166.83 ? 235 ALA A CB  1 
ATOM 807  N N   . GLU A 1 236 ? 112.780 144.899 77.624  1.00 175.38 ? 236 GLU A N   1 
ATOM 808  C CA  . GLU A 1 236 ? 111.601 144.927 76.765  1.00 174.33 ? 236 GLU A CA  1 
ATOM 809  C C   . GLU A 1 236 ? 110.651 146.051 77.163  1.00 174.87 ? 236 GLU A C   1 
ATOM 810  O O   . GLU A 1 236 ? 110.278 146.883 76.328  1.00 175.93 ? 236 GLU A O   1 
ATOM 811  C CB  . GLU A 1 236 ? 110.885 143.576 76.813  1.00 173.17 ? 236 GLU A CB  1 
ATOM 812  N N   . ASP A 1 237 ? 110.243 146.085 78.434  1.00 173.81 ? 237 ASP A N   1 
ATOM 813  C CA  . ASP A 1 237 ? 109.298 147.101 78.887  1.00 174.72 ? 237 ASP A CA  1 
ATOM 814  C C   . ASP A 1 237 ? 109.897 148.500 78.803  1.00 176.05 ? 237 ASP A C   1 
ATOM 815  O O   . ASP A 1 237 ? 109.207 149.453 78.421  1.00 176.43 ? 237 ASP A O   1 
ATOM 816  C CB  . ASP A 1 237 ? 108.847 146.797 80.316  1.00 173.55 ? 237 ASP A CB  1 
ATOM 817  N N   . GLU A 1 238 ? 111.172 148.644 79.178  1.00 169.07 ? 238 GLU A N   1 
ATOM 818  C CA  . GLU A 1 238 ? 111.891 149.917 79.165  1.00 167.53 ? 238 GLU A CA  1 
ATOM 819  C C   . GLU A 1 238 ? 111.282 150.938 80.122  1.00 167.86 ? 238 GLU A C   1 
ATOM 820  O O   . GLU A 1 238 ? 111.730 152.088 80.174  1.00 167.43 ? 238 GLU A O   1 
ATOM 821  C CB  . GLU A 1 238 ? 111.948 150.492 77.745  1.00 166.47 ? 238 GLU A CB  1 
ATOM 822  N N   . GLU A 1 239 ? 110.263 150.532 80.882  1.00 161.69 ? 239 GLU A N   1 
ATOM 823  C CA  . GLU A 1 239 ? 109.648 151.397 81.878  1.00 160.01 ? 239 GLU A CA  1 
ATOM 824  C C   . GLU A 1 239 ? 109.410 150.716 83.217  1.00 160.40 ? 239 GLU A C   1 
ATOM 825  O O   . GLU A 1 239 ? 109.151 151.416 84.203  1.00 160.82 ? 239 GLU A O   1 
ATOM 826  C CB  . GLU A 1 239 ? 108.311 151.950 81.359  1.00 159.61 ? 239 GLU A CB  1 
ATOM 827  N N   . MET A 1 240 ? 109.486 149.391 83.288  1.00 165.84 ? 240 MET A N   1 
ATOM 828  C CA  . MET A 1 240 ? 109.318 148.650 84.531  1.00 167.44 ? 240 MET A CA  1 
ATOM 829  C C   . MET A 1 240 ? 110.685 148.320 85.114  1.00 167.25 ? 240 MET A C   1 
ATOM 830  O O   . MET A 1 240 ? 111.553 147.791 84.412  1.00 166.62 ? 240 MET A O   1 
ATOM 831  C CB  . MET A 1 240 ? 108.514 147.370 84.301  1.00 167.21 ? 240 MET A CB  1 
ATOM 832  C CG  . MET A 1 240 ? 108.238 146.579 85.569  1.00 166.05 ? 240 MET A CG  1 
ATOM 833  S SD  . MET A 1 240 ? 107.193 145.141 85.273  1.00 167.53 ? 240 MET A SD  1 
ATOM 834  C CE  . MET A 1 240 ? 105.583 145.915 85.149  1.00 166.28 ? 240 MET A CE  1 
ATOM 835  N N   . ASN A 1 241 ? 110.874 148.639 86.392  1.00 150.48 ? 241 ASN A N   1 
ATOM 836  C CA  . ASN A 1 241 ? 112.149 148.385 87.044  1.00 149.58 ? 241 ASN A CA  1 
ATOM 837  C C   . ASN A 1 241 ? 112.411 146.889 87.178  1.00 149.91 ? 241 ASN A C   1 
ATOM 838  O O   . ASN A 1 241 ? 111.496 146.087 87.382  1.00 148.26 ? 241 ASN A O   1 
ATOM 839  C CB  . ASN A 1 241 ? 112.178 149.037 88.426  1.00 147.81 ? 241 ASN A CB  1 
ATOM 840  C CG  . ASN A 1 241 ? 113.585 149.236 88.945  1.00 147.33 ? 241 ASN A CG  1 
ATOM 841  O OD1 . ASN A 1 241 ? 114.111 148.396 89.675  1.00 146.72 ? 241 ASN A OD1 1 
ATOM 842  N ND2 . ASN A 1 241 ? 114.203 150.351 88.574  1.00 147.77 ? 241 ASN A ND2 1 
ATOM 843  N N   . ARG A 1 242 ? 113.689 146.520 87.050  1.00 150.47 ? 242 ARG A N   1 
ATOM 844  C CA  . ARG A 1 242 ? 114.073 145.116 87.156  1.00 148.94 ? 242 ARG A CA  1 
ATOM 845  C C   . ARG A 1 242 ? 113.780 144.566 88.546  1.00 148.44 ? 242 ARG A C   1 
ATOM 846  O O   . ARG A 1 242 ? 113.297 143.437 88.688  1.00 147.07 ? 242 ARG A O   1 
ATOM 847  C CB  . ARG A 1 242 ? 115.554 144.950 86.812  1.00 146.94 ? 242 ARG A CB  1 
ATOM 848  C CG  . ARG A 1 242 ? 115.881 145.197 85.349  1.00 147.21 ? 242 ARG A CG  1 
ATOM 849  C CD  . ARG A 1 242 ? 117.346 144.916 85.056  1.00 148.97 ? 242 ARG A CD  1 
ATOM 850  N NE  . ARG A 1 242 ? 117.663 145.099 83.645  1.00 151.21 ? 242 ARG A NE  1 
ATOM 851  C CZ  . ARG A 1 242 ? 117.627 144.132 82.738  1.00 151.32 ? 242 ARG A CZ  1 
ATOM 852  N NH1 . ARG A 1 242 ? 117.293 142.893 83.061  1.00 150.03 ? 242 ARG A NH1 1 
ATOM 853  N NH2 . ARG A 1 242 ? 117.936 144.415 81.476  1.00 150.18 ? 242 ARG A NH2 1 
ATOM 854  N N   . MET A 1 243 ? 114.080 145.349 89.586  1.00 129.80 ? 243 MET A N   1 
ATOM 855  C CA  . MET A 1 243 ? 113.856 144.893 90.954  1.00 126.85 ? 243 MET A CA  1 
ATOM 856  C C   . MET A 1 243 ? 112.375 144.665 91.228  1.00 126.28 ? 243 MET A C   1 
ATOM 857  O O   . MET A 1 243 ? 112.002 143.691 91.893  1.00 127.64 ? 243 MET A O   1 
ATOM 858  C CB  . MET A 1 243 ? 114.436 145.903 91.944  1.00 127.32 ? 243 MET A CB  1 
ATOM 859  C CG  . MET A 1 243 ? 114.317 145.482 93.398  1.00 128.65 ? 243 MET A CG  1 
ATOM 860  S SD  . MET A 1 243 ? 115.310 144.027 93.778  1.00 126.82 ? 243 MET A SD  1 
ATOM 861  C CE  . MET A 1 243 ? 116.955 144.736 93.808  1.00 126.58 ? 243 MET A CE  1 
ATOM 862  N N   . HIS A 1 244 ? 111.514 145.556 90.729  1.00 126.69 ? 244 HIS A N   1 
ATOM 863  C CA  . HIS A 1 244 ? 110.077 145.372 90.905  1.00 127.84 ? 244 HIS A CA  1 
ATOM 864  C C   . HIS A 1 244 ? 109.584 144.126 90.183  1.00 127.23 ? 244 HIS A C   1 
ATOM 865  O O   . HIS A 1 244 ? 108.635 143.477 90.640  1.00 126.20 ? 244 HIS A O   1 
ATOM 866  C CB  . HIS A 1 244 ? 109.326 146.610 90.413  1.00 129.68 ? 244 HIS A CB  1 
ATOM 867  C CG  . HIS A 1 244 ? 109.486 147.803 91.302  1.00 130.18 ? 244 HIS A CG  1 
ATOM 868  N ND1 . HIS A 1 244 ? 110.692 148.450 91.469  1.00 130.07 ? 244 HIS A ND1 1 
ATOM 869  C CD2 . HIS A 1 244 ? 108.594 148.465 92.077  1.00 128.13 ? 244 HIS A CD2 1 
ATOM 870  C CE1 . HIS A 1 244 ? 110.536 149.460 92.305  1.00 128.40 ? 244 HIS A CE1 1 
ATOM 871  N NE2 . HIS A 1 244 ? 109.272 149.491 92.689  1.00 127.88 ? 244 HIS A NE2 1 
ATOM 872  N N   . ALA A 1 245 ? 110.206 143.782 89.053  1.00 119.95 ? 245 ALA A N   1 
ATOM 873  C CA  . ALA A 1 245 ? 109.840 142.560 88.346  1.00 119.60 ? 245 ALA A CA  1 
ATOM 874  C C   . ALA A 1 245 ? 110.134 141.329 89.193  1.00 119.17 ? 245 ALA A C   1 
ATOM 875  O O   . ALA A 1 245 ? 109.321 140.400 89.258  1.00 116.65 ? 245 ALA A O   1 
ATOM 876  C CB  . ALA A 1 245 ? 110.578 142.484 87.010  1.00 120.30 ? 245 ALA A CB  1 
ATOM 877  N N   . SER A 1 246 ? 111.301 141.301 89.842  1.00 112.15 ? 246 SER A N   1 
ATOM 878  C CA  . SER A 1 246 ? 111.640 140.178 90.711  1.00 110.41 ? 246 SER A CA  1 
ATOM 879  C C   . SER A 1 246 ? 110.716 140.112 91.921  1.00 107.92 ? 246 SER A C   1 
ATOM 880  O O   . SER A 1 246 ? 110.307 139.020 92.334  1.00 105.84 ? 246 SER A O   1 
ATOM 881  C CB  . SER A 1 246 ? 113.100 140.282 91.153  1.00 110.56 ? 246 SER A CB  1 
ATOM 882  O OG  . SER A 1 246 ? 113.977 140.149 90.048  1.00 111.30 ? 246 SER A OG  1 
ATOM 883  N N   . MET A 1 247 ? 110.389 141.265 92.513  1.00 112.24 ? 247 MET A N   1 
ATOM 884  C CA  . MET A 1 247 ? 109.469 141.273 93.647  1.00 111.46 ? 247 MET A CA  1 
ATOM 885  C C   . MET A 1 247 ? 108.102 140.730 93.253  1.00 113.77 ? 247 MET A C   1 
ATOM 886  O O   . MET A 1 247 ? 107.490 139.959 94.002  1.00 115.07 ? 247 MET A O   1 
ATOM 887  C CB  . MET A 1 247 ? 109.337 142.689 94.207  1.00 112.34 ? 247 MET A CB  1 
ATOM 888  C CG  . MET A 1 247 ? 110.591 143.227 94.874  1.00 113.40 ? 247 MET A CG  1 
ATOM 889  S SD  . MET A 1 247 ? 110.388 144.930 95.430  1.00 120.22 ? 247 MET A SD  1 
ATOM 890  C CE  . MET A 1 247 ? 109.283 144.705 96.822  1.00 115.38 ? 247 MET A CE  1 
ATOM 891  N N   . LYS A 1 248 ? 107.602 141.129 92.080  1.00 102.06 ? 248 LYS A N   1 
ATOM 892  C CA  . LYS A 1 248 ? 106.375 140.534 91.559  1.00 100.34 ? 248 LYS A CA  1 
ATOM 893  C C   . LYS A 1 248 ? 106.564 139.051 91.270  1.00 100.24 ? 248 LYS A C   1 
ATOM 894  O O   . LYS A 1 248 ? 105.663 138.241 91.521  1.00 97.28  ? 248 LYS A O   1 
ATOM 895  C CB  . LYS A 1 248 ? 105.926 141.276 90.301  1.00 98.85  ? 248 LYS A CB  1 
ATOM 896  N N   . LEU A 1 249 ? 107.729 138.678 90.733  1.00 96.79  ? 249 LEU A N   1 
ATOM 897  C CA  . LEU A 1 249 ? 108.022 137.268 90.497  1.00 98.22  ? 249 LEU A CA  1 
ATOM 898  C C   . LEU A 1 249 ? 108.126 136.495 91.805  1.00 97.34  ? 249 LEU A C   1 
ATOM 899  O O   . LEU A 1 249 ? 107.676 135.346 91.888  1.00 96.15  ? 249 LEU A O   1 
ATOM 900  C CB  . LEU A 1 249 ? 109.312 137.130 89.687  1.00 94.94  ? 249 LEU A CB  1 
ATOM 901  C CG  . LEU A 1 249 ? 109.741 135.711 89.306  1.00 92.50  ? 249 LEU A CG  1 
ATOM 902  C CD1 . LEU A 1 249 ? 108.672 135.030 88.466  1.00 93.93  ? 249 LEU A CD1 1 
ATOM 903  C CD2 . LEU A 1 249 ? 111.075 135.727 88.574  1.00 91.15  ? 249 LEU A CD2 1 
ATOM 904  N N   . PHE A 1 250 ? 108.722 137.102 92.835  1.00 86.94  ? 250 PHE A N   1 
ATOM 905  C CA  . PHE A 1 250 ? 108.905 136.402 94.103  1.00 81.61  ? 250 PHE A CA  1 
ATOM 906  C C   . PHE A 1 250 ? 107.565 136.084 94.754  1.00 78.61  ? 250 PHE A C   1 
ATOM 907  O O   . PHE A 1 250 ? 107.313 134.943 95.159  1.00 78.26  ? 250 PHE A O   1 
ATOM 908  C CB  . PHE A 1 250 ? 109.776 137.233 95.046  1.00 82.43  ? 250 PHE A CB  1 
ATOM 909  C CG  . PHE A 1 250 ? 110.405 136.433 96.155  1.00 79.67  ? 250 PHE A CG  1 
ATOM 910  C CD1 . PHE A 1 250 ? 109.708 136.172 97.324  1.00 82.16  ? 250 PHE A CD1 1 
ATOM 911  C CD2 . PHE A 1 250 ? 111.694 135.945 96.029  1.00 77.76  ? 250 PHE A CD2 1 
ATOM 912  C CE1 . PHE A 1 250 ? 110.285 135.438 98.342  1.00 80.71  ? 250 PHE A CE1 1 
ATOM 913  C CE2 . PHE A 1 250 ? 112.275 135.209 97.044  1.00 77.64  ? 250 PHE A CE2 1 
ATOM 914  C CZ  . PHE A 1 250 ? 111.571 134.957 98.202  1.00 79.29  ? 250 PHE A CZ  1 
ATOM 915  N N   . ASP A 1 251 ? 106.685 137.083 94.861  1.00 92.64  ? 251 ASP A N   1 
ATOM 916  C CA  . ASP A 1 251 ? 105.395 136.859 95.500  1.00 99.65  ? 251 ASP A CA  1 
ATOM 917  C C   . ASP A 1 251 ? 104.476 135.990 94.651  1.00 96.68  ? 251 ASP A C   1 
ATOM 918  O O   . ASP A 1 251 ? 103.550 135.377 95.192  1.00 95.18  ? 251 ASP A O   1 
ATOM 919  C CB  . ASP A 1 251 ? 104.731 138.206 95.811  1.00 98.50  ? 251 ASP A CB  1 
ATOM 920  C CG  . ASP A 1 251 ? 103.399 138.388 95.102  1.00 99.81  ? 251 ASP A CG  1 
ATOM 921  O OD1 . ASP A 1 251 ? 102.373 137.887 95.610  1.00 98.34  ? 251 ASP A OD1 1 
ATOM 922  O OD2 . ASP A 1 251 ? 103.380 139.035 94.035  1.00 100.61 ? 251 ASP A OD2 1 
ATOM 923  N N   . SER A 1 252 ? 104.716 135.912 93.341  1.00 79.80  ? 252 SER A N   1 
ATOM 924  C CA  . SER A 1 252 ? 103.990 134.947 92.524  1.00 81.07  ? 252 SER A CA  1 
ATOM 925  C C   . SER A 1 252 ? 104.442 133.523 92.818  1.00 85.83  ? 252 SER A C   1 
ATOM 926  O O   . SER A 1 252 ? 103.667 132.576 92.641  1.00 85.75  ? 252 SER A O   1 
ATOM 927  C CB  . SER A 1 252 ? 104.169 135.268 91.041  1.00 84.63  ? 252 SER A CB  1 
ATOM 928  O OG  . SER A 1 252 ? 105.530 135.173 90.660  1.00 88.44  ? 252 SER A OG  1 
ATOM 929  N N   . ILE A 1 253 ? 105.683 133.356 93.264  1.00 86.09  ? 253 ILE A N   1 
ATOM 930  C CA  . ILE A 1 253 ? 106.220 132.044 93.611  1.00 84.91  ? 253 ILE A CA  1 
ATOM 931  C C   . ILE A 1 253 ? 106.041 131.745 95.092  1.00 84.00  ? 253 ILE A C   1 
ATOM 932  O O   . ILE A 1 253 ? 105.605 130.654 95.468  1.00 79.99  ? 253 ILE A O   1 
ATOM 933  C CB  . ILE A 1 253 ? 107.704 131.952 93.195  1.00 80.40  ? 253 ILE A CB  1 
ATOM 934  C CG1 . ILE A 1 253 ? 107.846 132.105 91.679  1.00 81.97  ? 253 ILE A CG1 1 
ATOM 935  C CG2 . ILE A 1 253 ? 108.311 130.641 93.665  1.00 77.85  ? 253 ILE A CG2 1 
ATOM 936  C CD1 . ILE A 1 253 ? 107.068 131.080 90.885  1.00 83.19  ? 253 ILE A CD1 1 
ATOM 937  N N   . CYS A 1 254 ? 106.383 132.708 95.953  1.00 87.64  ? 254 CYS A N   1 
ATOM 938  C CA  . CYS A 1 254 ? 106.302 132.483 97.393  1.00 83.35  ? 254 CYS A CA  1 
ATOM 939  C C   . CYS A 1 254 ? 104.868 132.223 97.833  1.00 81.80  ? 254 CYS A C   1 
ATOM 940  O O   . CYS A 1 254 ? 104.617 131.352 98.673  1.00 82.83  ? 254 CYS A O   1 
ATOM 941  C CB  . CYS A 1 254 ? 106.889 133.677 98.146  1.00 82.61  ? 254 CYS A CB  1 
ATOM 942  S SG  . CYS A 1 254 ? 107.135 133.395 99.916  1.00 90.56  ? 254 CYS A SG  1 
ATOM 943  N N   . ASN A 1 255 ? 103.915 132.967 97.282  1.00 86.96  ? 255 ASN A N   1 
ATOM 944  C CA  . ASN A 1 255 ? 102.514 132.831 97.650  1.00 88.43  ? 255 ASN A CA  1 
ATOM 945  C C   . ASN A 1 255 ? 101.766 131.849 96.757  1.00 88.83  ? 255 ASN A C   1 
ATOM 946  O O   . ASN A 1 255 ? 100.540 131.744 96.865  1.00 89.85  ? 255 ASN A O   1 
ATOM 947  C CB  . ASN A 1 255 ? 101.823 134.196 97.617  1.00 88.46  ? 255 ASN A CB  1 
ATOM 948  C CG  . ASN A 1 255 ? 102.509 135.218 98.502  1.00 92.12  ? 255 ASN A CG  1 
ATOM 949  O OD1 . ASN A 1 255 ? 103.208 134.865 99.452  1.00 91.54  ? 255 ASN A OD1 1 
ATOM 950  N ND2 . ASN A 1 255 ? 102.312 136.495 98.193  1.00 90.44  ? 255 ASN A ND2 1 
ATOM 951  N N   . ASN A 1 256 ? 102.470 131.139 95.876  1.00 76.56  ? 256 ASN A N   1 
ATOM 952  C CA  . ASN A 1 256 ? 101.827 130.139 95.036  1.00 75.14  ? 256 ASN A CA  1 
ATOM 953  C C   . ASN A 1 256 ? 101.244 129.017 95.888  1.00 75.38  ? 256 ASN A C   1 
ATOM 954  O O   . ASN A 1 256 ? 101.825 128.616 96.900  1.00 77.57  ? 256 ASN A O   1 
ATOM 955  C CB  . ASN A 1 256 ? 102.826 129.571 94.027  1.00 75.07  ? 256 ASN A CB  1 
ATOM 956  C CG  . ASN A 1 256 ? 102.148 128.835 92.888  1.00 76.18  ? 256 ASN A CG  1 
ATOM 957  O OD1 . ASN A 1 256 ? 101.893 127.634 92.974  1.00 77.13  ? 256 ASN A OD1 1 
ATOM 958  N ND2 . ASN A 1 256 ? 101.854 129.555 91.812  1.00 73.91  ? 256 ASN A ND2 1 
ATOM 959  N N   . LYS A 1 257 ? 100.082 128.511 95.468  1.00 67.59  ? 257 LYS A N   1 
ATOM 960  C CA  . LYS A 1 257 ? 99.369  127.512 96.256  1.00 70.93  ? 257 LYS A CA  1 
ATOM 961  C C   . LYS A 1 257 ? 100.090 126.170 96.308  1.00 67.21  ? 257 LYS A C   1 
ATOM 962  O O   . LYS A 1 257 ? 99.873  125.405 97.253  1.00 64.50  ? 257 LYS A O   1 
ATOM 963  C CB  . LYS A 1 257 ? 97.957  127.317 95.701  1.00 72.31  ? 257 LYS A CB  1 
ATOM 964  C CG  . LYS A 1 257 ? 97.914  126.905 94.238  1.00 68.38  ? 257 LYS A CG  1 
ATOM 965  C CD  . LYS A 1 257 ? 96.485  126.668 93.777  1.00 67.33  ? 257 LYS A CD  1 
ATOM 966  C CE  . LYS A 1 257 ? 96.436  126.257 92.315  1.00 67.14  ? 257 LYS A CE  1 
ATOM 967  N NZ  . LYS A 1 257 ? 95.039  126.035 91.850  1.00 67.11  ? 257 LYS A NZ  1 
ATOM 968  N N   . TRP A 1 258 ? 100.938 125.863 95.324  1.00 59.65  ? 258 TRP A N   1 
ATOM 969  C CA  . TRP A 1 258 ? 101.670 124.602 95.349  1.00 62.03  ? 258 TRP A CA  1 
ATOM 970  C C   . TRP A 1 258 ? 102.912 124.656 96.223  1.00 62.77  ? 258 TRP A C   1 
ATOM 971  O O   . TRP A 1 258 ? 103.462 123.603 96.562  1.00 62.43  ? 258 TRP A O   1 
ATOM 972  C CB  . TRP A 1 258 ? 102.064 124.188 93.930  1.00 61.84  ? 258 TRP A CB  1 
ATOM 973  C CG  . TRP A 1 258 ? 100.908 124.140 92.991  1.00 60.69  ? 258 TRP A CG  1 
ATOM 974  C CD1 . TRP A 1 258 ? 100.728 124.895 91.871  1.00 58.43  ? 258 TRP A CD1 1 
ATOM 975  C CD2 . TRP A 1 258 ? 99.756  123.299 93.099  1.00 60.47  ? 258 TRP A CD2 1 
ATOM 976  N NE1 . TRP A 1 258 ? 99.538  124.570 91.268  1.00 58.57  ? 258 TRP A NE1 1 
ATOM 977  C CE2 . TRP A 1 258 ? 98.922  123.593 92.004  1.00 61.20  ? 258 TRP A CE2 1 
ATOM 978  C CE3 . TRP A 1 258 ? 99.350  122.323 94.014  1.00 57.97  ? 258 TRP A CE3 1 
ATOM 979  C CZ2 . TRP A 1 258 ? 97.708  122.947 91.799  1.00 58.65  ? 258 TRP A CZ2 1 
ATOM 980  C CZ3 . TRP A 1 258 ? 98.145  121.684 93.810  1.00 58.66  ? 258 TRP A CZ3 1 
ATOM 981  C CH2 . TRP A 1 258 ? 97.338  121.998 92.712  1.00 58.54  ? 258 TRP A CH2 1 
ATOM 982  N N   . PHE A 1 259 ? 103.362 125.849 96.595  1.00 67.98  ? 259 PHE A N   1 
ATOM 983  C CA  . PHE A 1 259 ? 104.523 126.029 97.457  1.00 64.68  ? 259 PHE A CA  1 
ATOM 984  C C   . PHE A 1 259 ? 104.100 126.555 98.826  1.00 69.04  ? 259 PHE A C   1 
ATOM 985  O O   . PHE A 1 259 ? 104.756 127.420 99.408  1.00 69.90  ? 259 PHE A O   1 
ATOM 986  C CB  . PHE A 1 259 ? 105.534 126.962 96.797  1.00 69.74  ? 259 PHE A CB  1 
ATOM 987  C CG  . PHE A 1 259 ? 106.046 126.457 95.477  1.00 64.56  ? 259 PHE A CG  1 
ATOM 988  C CD1 . PHE A 1 259 ? 106.474 125.147 95.341  1.00 60.63  ? 259 PHE A CD1 1 
ATOM 989  C CD2 . PHE A 1 259 ? 106.086 127.288 94.368  1.00 61.02  ? 259 PHE A CD2 1 
ATOM 990  C CE1 . PHE A 1 259 ? 106.942 124.679 94.129  1.00 60.99  ? 259 PHE A CE1 1 
ATOM 991  C CE2 . PHE A 1 259 ? 106.553 126.824 93.154  1.00 60.45  ? 259 PHE A CE2 1 
ATOM 992  C CZ  . PHE A 1 259 ? 106.981 125.518 93.035  1.00 64.24  ? 259 PHE A CZ  1 
ATOM 993  N N   . THR A 1 260 ? 102.982 126.037 99.344  1.00 86.70  ? 260 THR A N   1 
ATOM 994  C CA  . THR A 1 260 ? 102.461 126.510 100.624 1.00 90.20  ? 260 THR A CA  1 
ATOM 995  C C   . THR A 1 260 ? 103.439 126.234 101.759 1.00 86.56  ? 260 THR A C   1 
ATOM 996  O O   . THR A 1 260 ? 103.656 127.091 102.624 1.00 84.70  ? 260 THR A O   1 
ATOM 997  C CB  . THR A 1 260 ? 101.108 125.858 100.911 1.00 87.61  ? 260 THR A CB  1 
ATOM 998  O OG1 . THR A 1 260 ? 100.199 126.153 99.844  1.00 89.35  ? 260 THR A OG1 1 
ATOM 999  C CG2 . THR A 1 260 ? 100.529 126.381 102.216 1.00 84.20  ? 260 THR A CG2 1 
ATOM 1000 N N   . ASP A 1 261 ? 104.032 125.045 101.780 1.00 77.01  ? 261 ASP A N   1 
ATOM 1001 C CA  . ASP A 1 261 ? 104.960 124.646 102.829 1.00 74.93  ? 261 ASP A CA  1 
ATOM 1002 C C   . ASP A 1 261 ? 106.318 124.285 102.239 1.00 70.90  ? 261 ASP A C   1 
ATOM 1003 O O   . ASP A 1 261 ? 107.008 123.383 102.717 1.00 77.90  ? 261 ASP A O   1 
ATOM 1004 C CB  . ASP A 1 261 ? 104.395 123.482 103.639 1.00 75.16  ? 261 ASP A CB  1 
ATOM 1005 C CG  . ASP A 1 261 ? 103.902 122.348 102.763 1.00 80.73  ? 261 ASP A CG  1 
ATOM 1006 O OD1 . ASP A 1 261 ? 103.926 122.501 101.524 1.00 83.25  ? 261 ASP A OD1 1 
ATOM 1007 O OD2 . ASP A 1 261 ? 103.490 121.304 103.311 1.00 82.69  ? 261 ASP A OD2 1 
ATOM 1008 N N   . THR A 1 262 ? 106.715 124.996 101.187 1.00 46.31  ? 262 THR A N   1 
ATOM 1009 C CA  . THR A 1 262 ? 107.999 124.793 100.524 1.00 46.06  ? 262 THR A CA  1 
ATOM 1010 C C   . THR A 1 262 ? 108.902 125.973 100.859 1.00 50.91  ? 262 THR A C   1 
ATOM 1011 O O   . THR A 1 262 ? 108.635 127.103 100.438 1.00 52.85  ? 262 THR A O   1 
ATOM 1012 C CB  . THR A 1 262 ? 107.824 124.650 99.013  1.00 48.74  ? 262 THR A CB  1 
ATOM 1013 O OG1 . THR A 1 262 ? 106.925 123.569 98.734  1.00 50.30  ? 262 THR A OG1 1 
ATOM 1014 C CG2 . THR A 1 262 ? 109.162 124.374 98.346  1.00 58.28  ? 262 THR A CG2 1 
ATOM 1015 N N   . SER A 1 263 ? 109.960 125.713 101.621 1.00 56.76  ? 263 SER A N   1 
ATOM 1016 C CA  . SER A 1 263 ? 110.909 126.765 101.951 1.00 55.58  ? 263 SER A CA  1 
ATOM 1017 C C   . SER A 1 263 ? 111.592 127.277 100.689 1.00 51.97  ? 263 SER A C   1 
ATOM 1018 O O   . SER A 1 263 ? 111.853 126.526 99.747  1.00 63.75  ? 263 SER A O   1 
ATOM 1019 C CB  . SER A 1 263 ? 111.952 126.256 102.945 1.00 56.22  ? 263 SER A CB  1 
ATOM 1020 O OG  . SER A 1 263 ? 111.342 125.804 104.142 1.00 56.64  ? 263 SER A OG  1 
ATOM 1021 N N   . ILE A 1 264 ? 111.880 128.575 100.677 1.00 42.10  ? 264 ILE A N   1 
ATOM 1022 C CA  . ILE A 1 264 ? 112.490 129.241 99.534  1.00 42.71  ? 264 ILE A CA  1 
ATOM 1023 C C   . ILE A 1 264 ? 113.858 129.758 99.949  1.00 40.37  ? 264 ILE A C   1 
ATOM 1024 O O   . ILE A 1 264 ? 113.980 130.472 100.951 1.00 58.08  ? 264 ILE A O   1 
ATOM 1025 C CB  . ILE A 1 264 ? 111.611 130.387 99.005  1.00 42.09  ? 264 ILE A CB  1 
ATOM 1026 C CG1 . ILE A 1 264 ? 110.312 129.831 98.422  1.00 37.92  ? 264 ILE A CG1 1 
ATOM 1027 C CG2 . ILE A 1 264 ? 112.360 131.201 97.965  1.00 40.72  ? 264 ILE A CG2 1 
ATOM 1028 C CD1 . ILE A 1 264 ? 109.451 130.876 97.773  1.00 40.55  ? 264 ILE A CD1 1 
ATOM 1029 N N   . ILE A 1 265 ? 114.879 129.397 99.180  1.00 26.65  ? 265 ILE A N   1 
ATOM 1030 C CA  . ILE A 1 265 ? 116.225 129.925 99.363  1.00 44.74  ? 265 ILE A CA  1 
ATOM 1031 C C   . ILE A 1 265 ? 116.353 131.168 98.491  1.00 52.68  ? 265 ILE A C   1 
ATOM 1032 O O   . ILE A 1 265 ? 116.386 131.076 97.261  1.00 62.62  ? 265 ILE A O   1 
ATOM 1033 C CB  . ILE A 1 265 ? 117.294 128.883 99.014  1.00 43.83  ? 265 ILE A CB  1 
ATOM 1034 C CG1 . ILE A 1 265 ? 117.139 127.645 99.898  1.00 36.33  ? 265 ILE A CG1 1 
ATOM 1035 C CG2 . ILE A 1 265 ? 118.682 129.482 99.154  1.00 44.19  ? 265 ILE A CG2 1 
ATOM 1036 C CD1 . ILE A 1 265 ? 118.128 126.546 99.586  1.00 38.28  ? 265 ILE A CD1 1 
ATOM 1037 N N   . LEU A 1 266 ? 116.423 132.332 99.130  1.00 64.51  ? 266 LEU A N   1 
ATOM 1038 C CA  . LEU A 1 266 ? 116.467 133.617 98.442  1.00 60.99  ? 266 LEU A CA  1 
ATOM 1039 C C   . LEU A 1 266 ? 117.920 134.054 98.313  1.00 59.20  ? 266 LEU A C   1 
ATOM 1040 O O   . LEU A 1 266 ? 118.585 134.328 99.317  1.00 61.42  ? 266 LEU A O   1 
ATOM 1041 C CB  . LEU A 1 266 ? 115.649 134.660 99.200  1.00 68.55  ? 266 LEU A CB  1 
ATOM 1042 C CG  . LEU A 1 266 ? 115.894 136.126 98.832  1.00 72.60  ? 266 LEU A CG  1 
ATOM 1043 C CD1 . LEU A 1 266 ? 115.550 136.397 97.375  1.00 72.01  ? 266 LEU A CD1 1 
ATOM 1044 C CD2 . LEU A 1 266 ? 115.121 137.054 99.758  1.00 73.37  ? 266 LEU A CD2 1 
ATOM 1045 N N   . PHE A 1 267 ? 118.412 134.109 97.080  1.00 73.13  ? 267 PHE A N   1 
ATOM 1046 C CA  . PHE A 1 267 ? 119.760 134.579 96.794  1.00 80.93  ? 267 PHE A CA  1 
ATOM 1047 C C   . PHE A 1 267 ? 119.711 136.035 96.351  1.00 87.59  ? 267 PHE A C   1 
ATOM 1048 O O   . PHE A 1 267 ? 118.920 136.397 95.473  1.00 90.87  ? 267 PHE A O   1 
ATOM 1049 C CB  . PHE A 1 267 ? 120.423 133.722 95.714  1.00 83.90  ? 267 PHE A CB  1 
ATOM 1050 C CG  . PHE A 1 267 ? 121.098 132.490 96.245  1.00 82.77  ? 267 PHE A CG  1 
ATOM 1051 C CD1 . PHE A 1 267 ? 121.122 132.228 97.604  1.00 81.03  ? 267 PHE A CD1 1 
ATOM 1052 C CD2 . PHE A 1 267 ? 121.714 131.596 95.384  1.00 84.05  ? 267 PHE A CD2 1 
ATOM 1053 C CE1 . PHE A 1 267 ? 121.744 131.096 98.094  1.00 80.96  ? 267 PHE A CE1 1 
ATOM 1054 C CE2 . PHE A 1 267 ? 122.338 130.462 95.869  1.00 81.44  ? 267 PHE A CE2 1 
ATOM 1055 C CZ  . PHE A 1 267 ? 122.352 130.213 97.226  1.00 80.29  ? 267 PHE A CZ  1 
ATOM 1056 N N   . LEU A 1 268 ? 120.556 136.863 96.957  1.00 99.14  ? 268 LEU A N   1 
ATOM 1057 C CA  . LEU A 1 268 ? 120.701 138.271 96.594  1.00 98.89  ? 268 LEU A CA  1 
ATOM 1058 C C   . LEU A 1 268 ? 122.070 138.413 95.932  1.00 99.74  ? 268 LEU A C   1 
ATOM 1059 O O   . LEU A 1 268 ? 123.064 138.728 96.588  1.00 100.40 ? 268 LEU A O   1 
ATOM 1060 C CB  . LEU A 1 268 ? 120.558 139.177 97.814  1.00 98.77  ? 268 LEU A CB  1 
ATOM 1061 C CG  . LEU A 1 268 ? 119.232 139.092 98.572  1.00 97.07  ? 268 LEU A CG  1 
ATOM 1062 C CD1 . LEU A 1 268 ? 119.209 140.086 99.724  1.00 96.37  ? 268 LEU A CD1 1 
ATOM 1063 C CD2 . LEU A 1 268 ? 118.063 139.333 97.630  1.00 92.43  ? 268 LEU A CD2 1 
ATOM 1064 N N   . ASN A 1 269 ? 122.111 138.182 94.623  1.00 109.30 ? 269 ASN A N   1 
ATOM 1065 C CA  . ASN A 1 269 ? 123.376 138.127 93.909  1.00 111.86 ? 269 ASN A CA  1 
ATOM 1066 C C   . ASN A 1 269 ? 123.911 139.530 93.629  1.00 113.44 ? 269 ASN A C   1 
ATOM 1067 O O   . ASN A 1 269 ? 123.246 140.543 93.862  1.00 112.61 ? 269 ASN A O   1 
ATOM 1068 C CB  . ASN A 1 269 ? 123.217 137.356 92.601  1.00 110.20 ? 269 ASN A CB  1 
ATOM 1069 C CG  . ASN A 1 269 ? 122.666 135.964 92.813  1.00 111.40 ? 269 ASN A CG  1 
ATOM 1070 O OD1 . ASN A 1 269 ? 123.299 135.120 93.447  1.00 112.63 ? 269 ASN A OD1 1 
ATOM 1071 N ND2 . ASN A 1 269 ? 121.474 135.716 92.285  1.00 109.39 ? 269 ASN A ND2 1 
ATOM 1072 N N   . LYS A 1 270 ? 125.138 139.566 93.109  1.00 124.18 ? 270 LYS A N   1 
ATOM 1073 C CA  . LYS A 1 270 ? 125.828 140.804 92.751  1.00 123.85 ? 270 LYS A CA  1 
ATOM 1074 C C   . LYS A 1 270 ? 125.889 141.759 93.941  1.00 126.77 ? 270 LYS A C   1 
ATOM 1075 O O   . LYS A 1 270 ? 125.625 142.959 93.828  1.00 127.92 ? 270 LYS A O   1 
ATOM 1076 C CB  . LYS A 1 270 ? 125.169 141.463 91.539  1.00 122.40 ? 270 LYS A CB  1 
ATOM 1077 C CG  . LYS A 1 270 ? 125.178 140.587 90.296  1.00 124.47 ? 270 LYS A CG  1 
ATOM 1078 C CD  . LYS A 1 270 ? 124.528 141.284 89.115  1.00 126.29 ? 270 LYS A CD  1 
ATOM 1079 C CE  . LYS A 1 270 ? 124.551 140.406 87.876  1.00 125.92 ? 270 LYS A CE  1 
ATOM 1080 N NZ  . LYS A 1 270 ? 123.930 141.085 86.706  1.00 125.79 ? 270 LYS A NZ  1 
ATOM 1081 N N   . LYS A 1 271 ? 126.240 141.204 95.103  1.00 133.50 ? 271 LYS A N   1 
ATOM 1082 C CA  . LYS A 1 271 ? 126.325 142.011 96.315  1.00 132.83 ? 271 LYS A CA  1 
ATOM 1083 C C   . LYS A 1 271 ? 127.455 143.028 96.222  1.00 134.64 ? 271 LYS A C   1 
ATOM 1084 O O   . LYS A 1 271 ? 127.316 144.165 96.689  1.00 134.88 ? 271 LYS A O   1 
ATOM 1085 C CB  . LYS A 1 271 ? 126.509 141.109 97.535  1.00 129.92 ? 271 LYS A CB  1 
ATOM 1086 N N   . ASP A 1 272 ? 128.584 142.634 95.629  1.00 137.68 ? 272 ASP A N   1 
ATOM 1087 C CA  . ASP A 1 272 ? 129.721 143.542 95.520  1.00 136.98 ? 272 ASP A CA  1 
ATOM 1088 C C   . ASP A 1 272 ? 129.433 144.675 94.544  1.00 136.04 ? 272 ASP A C   1 
ATOM 1089 O O   . ASP A 1 272 ? 129.802 145.828 94.796  1.00 136.28 ? 272 ASP A O   1 
ATOM 1090 C CB  . ASP A 1 272 ? 130.970 142.769 95.098  1.00 137.53 ? 272 ASP A CB  1 
ATOM 1091 C CG  . ASP A 1 272 ? 130.773 142.003 93.804  1.00 138.01 ? 272 ASP A CG  1 
ATOM 1092 O OD1 . ASP A 1 272 ? 129.618 141.642 93.495  1.00 138.01 ? 272 ASP A OD1 1 
ATOM 1093 O OD2 . ASP A 1 272 ? 131.773 141.764 93.095  1.00 138.21 ? 272 ASP A OD2 1 
ATOM 1094 N N   . LEU A 1 273 ? 128.778 144.367 93.421  1.00 135.93 ? 273 LEU A N   1 
ATOM 1095 C CA  . LEU A 1 273 ? 128.452 145.407 92.452  1.00 137.03 ? 273 LEU A CA  1 
ATOM 1096 C C   . LEU A 1 273 ? 127.393 146.358 92.993  1.00 137.36 ? 273 LEU A C   1 
ATOM 1097 O O   . LEU A 1 273 ? 127.363 147.534 92.613  1.00 136.70 ? 273 LEU A O   1 
ATOM 1098 C CB  . LEU A 1 273 ? 127.981 144.775 91.141  1.00 136.93 ? 273 LEU A CB  1 
ATOM 1099 C CG  . LEU A 1 273 ? 127.806 145.717 89.948  1.00 138.06 ? 273 LEU A CG  1 
ATOM 1100 C CD1 . LEU A 1 273 ? 129.115 146.420 89.622  1.00 137.57 ? 273 LEU A CD1 1 
ATOM 1101 C CD2 . LEU A 1 273 ? 127.279 144.964 88.735  1.00 136.34 ? 273 LEU A CD2 1 
ATOM 1102 N N   . PHE A 1 274 ? 126.518 145.867 93.874  1.00 137.79 ? 274 PHE A N   1 
ATOM 1103 C CA  . PHE A 1 274 ? 125.490 146.722 94.461  1.00 138.07 ? 274 PHE A CA  1 
ATOM 1104 C C   . PHE A 1 274 ? 126.111 147.811 95.327  1.00 139.04 ? 274 PHE A C   1 
ATOM 1105 O O   . PHE A 1 274 ? 125.632 148.951 95.344  1.00 139.77 ? 274 PHE A O   1 
ATOM 1106 C CB  . PHE A 1 274 ? 124.506 145.881 95.274  1.00 137.52 ? 274 PHE A CB  1 
ATOM 1107 C CG  . PHE A 1 274 ? 123.467 146.692 95.994  1.00 137.33 ? 274 PHE A CG  1 
ATOM 1108 C CD1 . PHE A 1 274 ? 122.382 147.214 95.309  1.00 137.70 ? 274 PHE A CD1 1 
ATOM 1109 C CD2 . PHE A 1 274 ? 123.571 146.930 97.354  1.00 138.33 ? 274 PHE A CD2 1 
ATOM 1110 C CE1 . PHE A 1 274 ? 121.423 147.960 95.966  1.00 139.23 ? 274 PHE A CE1 1 
ATOM 1111 C CE2 . PHE A 1 274 ? 122.615 147.676 98.017  1.00 138.88 ? 274 PHE A CE2 1 
ATOM 1112 C CZ  . PHE A 1 274 ? 121.539 148.191 97.321  1.00 139.36 ? 274 PHE A CZ  1 
ATOM 1113 N N   . GLU A 1 275 ? 127.173 147.472 96.063  1.00 142.50 ? 275 GLU A N   1 
ATOM 1114 C CA  . GLU A 1 275 ? 127.824 148.449 96.930  1.00 143.38 ? 275 GLU A CA  1 
ATOM 1115 C C   . GLU A 1 275 ? 128.410 149.601 96.124  1.00 142.46 ? 275 GLU A C   1 
ATOM 1116 O O   . GLU A 1 275 ? 128.350 150.759 96.549  1.00 141.66 ? 275 GLU A O   1 
ATOM 1117 C CB  . GLU A 1 275 ? 128.910 147.767 97.763  1.00 143.68 ? 275 GLU A CB  1 
ATOM 1118 C CG  . GLU A 1 275 ? 129.623 148.689 98.740  1.00 143.53 ? 275 GLU A CG  1 
ATOM 1119 C CD  . GLU A 1 275 ? 130.673 147.966 99.563  1.00 143.19 ? 275 GLU A CD  1 
ATOM 1120 O OE1 . GLU A 1 275 ? 130.837 146.742 99.377  1.00 142.91 ? 275 GLU A OE1 1 
ATOM 1121 O OE2 . GLU A 1 275 ? 131.334 148.622 100.395 1.00 141.98 ? 275 GLU A OE2 1 
ATOM 1122 N N   . GLU A 1 276 ? 129.023 149.302 94.979  1.00 136.37 ? 276 GLU A N   1 
ATOM 1123 C CA  . GLU A 1 276 ? 129.555 150.375 94.145  1.00 135.52 ? 276 GLU A CA  1 
ATOM 1124 C C   . GLU A 1 276 ? 128.438 151.257 93.598  1.00 136.42 ? 276 GLU A C   1 
ATOM 1125 O O   . GLU A 1 276 ? 128.566 152.486 93.569  1.00 135.68 ? 276 GLU A O   1 
ATOM 1126 C CB  . GLU A 1 276 ? 130.387 149.790 93.004  1.00 136.33 ? 276 GLU A CB  1 
ATOM 1127 C CG  . GLU A 1 276 ? 131.576 148.961 93.463  1.00 135.58 ? 276 GLU A CG  1 
ATOM 1128 C CD  . GLU A 1 276 ? 132.379 148.403 92.305  1.00 136.30 ? 276 GLU A CD  1 
ATOM 1129 O OE1 . GLU A 1 276 ? 132.022 148.686 91.142  1.00 137.25 ? 276 GLU A OE1 1 
ATOM 1130 O OE2 . GLU A 1 276 ? 133.367 147.683 92.556  1.00 135.13 ? 276 GLU A OE2 1 
ATOM 1131 N N   . LYS A 1 277 ? 127.335 150.644 93.157  1.00 141.12 ? 277 LYS A N   1 
ATOM 1132 C CA  . LYS A 1 277 ? 126.240 151.391 92.546  1.00 140.68 ? 277 LYS A CA  1 
ATOM 1133 C C   . LYS A 1 277 ? 125.411 152.200 93.541  1.00 140.77 ? 277 LYS A C   1 
ATOM 1134 O O   . LYS A 1 277 ? 124.698 153.116 93.118  1.00 141.29 ? 277 LYS A O   1 
ATOM 1135 C CB  . LYS A 1 277 ? 125.324 150.434 91.781  1.00 139.80 ? 277 LYS A CB  1 
ATOM 1136 N N   . ILE A 1 278 ? 125.470 151.894 94.840  1.00 145.86 ? 278 ILE A N   1 
ATOM 1137 C CA  . ILE A 1 278 ? 124.713 152.692 95.803  1.00 146.08 ? 278 ILE A CA  1 
ATOM 1138 C C   . ILE A 1 278 ? 125.311 154.090 95.926  1.00 147.10 ? 278 ILE A C   1 
ATOM 1139 O O   . ILE A 1 278 ? 124.583 155.079 96.074  1.00 146.37 ? 278 ILE A O   1 
ATOM 1140 C CB  . ILE A 1 278 ? 124.606 151.978 97.166  1.00 146.30 ? 278 ILE A CB  1 
ATOM 1141 C CG1 . ILE A 1 278 ? 123.587 152.690 98.056  1.00 147.29 ? 278 ILE A CG1 1 
ATOM 1142 C CG2 . ILE A 1 278 ? 125.933 151.937 97.891  1.00 146.72 ? 278 ILE A CG2 1 
ATOM 1143 C CD1 . ILE A 1 278 ? 122.168 152.609 97.540  1.00 147.17 ? 278 ILE A CD1 1 
ATOM 1144 N N   . LYS A 1 279 ? 126.642 154.193 95.877  1.00 144.80 ? 279 LYS A N   1 
ATOM 1145 C CA  . LYS A 1 279 ? 127.301 155.487 96.031  1.00 143.20 ? 279 LYS A CA  1 
ATOM 1146 C C   . LYS A 1 279 ? 126.901 156.448 94.918  1.00 143.29 ? 279 LYS A C   1 
ATOM 1147 O O   . LYS A 1 279 ? 126.692 157.642 95.163  1.00 144.14 ? 279 LYS A O   1 
ATOM 1148 C CB  . LYS A 1 279 ? 128.818 155.302 96.061  1.00 142.70 ? 279 LYS A CB  1 
ATOM 1149 N N   . LYS A 1 280 ? 126.787 155.946 93.687  1.00 144.64 ? 280 LYS A N   1 
ATOM 1150 C CA  . LYS A 1 280 ? 126.411 156.799 92.566  1.00 145.47 ? 280 LYS A CA  1 
ATOM 1151 C C   . LYS A 1 280 ? 124.897 156.946 92.462  1.00 145.68 ? 280 LYS A C   1 
ATOM 1152 O O   . LYS A 1 280 ? 124.376 158.066 92.439  1.00 144.02 ? 280 LYS A O   1 
ATOM 1153 C CB  . LYS A 1 280 ? 126.987 156.239 91.264  1.00 145.26 ? 280 LYS A CB  1 
ATOM 1154 N N   . SER A 1 281 ? 124.173 155.828 92.400  1.00 151.65 ? 281 SER A N   1 
ATOM 1155 C CA  . SER A 1 281 ? 122.729 155.872 92.231  1.00 151.49 ? 281 SER A CA  1 
ATOM 1156 C C   . SER A 1 281 ? 122.063 155.592 93.568  1.00 152.23 ? 281 SER A C   1 
ATOM 1157 O O   . SER A 1 281 ? 122.192 154.474 94.090  1.00 151.38 ? 281 SER A O   1 
ATOM 1158 C CB  . SER A 1 281 ? 122.277 154.854 91.186  1.00 150.21 ? 281 SER A CB  1 
ATOM 1159 O OG  . SER A 1 281 ? 120.868 154.868 91.038  1.00 150.05 ? 281 SER A OG  1 
ATOM 1160 N N   . PRO A 1 282 ? 121.356 156.553 94.159  1.00 156.28 ? 282 PRO A N   1 
ATOM 1161 C CA  . PRO A 1 282 ? 120.666 156.287 95.424  1.00 155.09 ? 282 PRO A CA  1 
ATOM 1162 C C   . PRO A 1 282 ? 119.522 155.301 95.254  1.00 154.38 ? 282 PRO A C   1 
ATOM 1163 O O   . PRO A 1 282 ? 118.929 155.173 94.180  1.00 154.13 ? 282 PRO A O   1 
ATOM 1164 C CB  . PRO A 1 282 ? 120.154 157.670 95.838  1.00 154.90 ? 282 PRO A CB  1 
ATOM 1165 C CG  . PRO A 1 282 ? 119.932 158.367 94.537  1.00 155.00 ? 282 PRO A CG  1 
ATOM 1166 C CD  . PRO A 1 282 ? 121.057 157.901 93.643  1.00 154.90 ? 282 PRO A CD  1 
ATOM 1167 N N   . LEU A 1 283 ? 119.217 154.595 96.345  1.00 152.09 ? 283 LEU A N   1 
ATOM 1168 C CA  . LEU A 1 283 ? 118.148 153.605 96.342  1.00 152.69 ? 283 LEU A CA  1 
ATOM 1169 C C   . LEU A 1 283 ? 116.762 154.227 96.228  1.00 153.48 ? 283 LEU A C   1 
ATOM 1170 O O   . LEU A 1 283 ? 115.803 153.507 95.926  1.00 151.46 ? 283 LEU A O   1 
ATOM 1171 C CB  . LEU A 1 283 ? 118.235 152.749 97.610  1.00 152.56 ? 283 LEU A CB  1 
ATOM 1172 C CG  . LEU A 1 283 ? 117.359 151.496 97.699  1.00 152.84 ? 283 LEU A CG  1 
ATOM 1173 C CD1 . LEU A 1 283 ? 117.662 150.550 96.548  1.00 152.28 ? 283 LEU A CD1 1 
ATOM 1174 C CD2 . LEU A 1 283 ? 117.546 150.798 99.037  1.00 153.04 ? 283 LEU A CD2 1 
ATOM 1175 N N   . THR A 1 284 ? 116.630 155.540 96.443  1.00 156.25 ? 284 THR A N   1 
ATOM 1176 C CA  . THR A 1 284 ? 115.317 156.171 96.380  1.00 155.14 ? 284 THR A CA  1 
ATOM 1177 C C   . THR A 1 284 ? 114.698 156.093 94.991  1.00 154.35 ? 284 THR A C   1 
ATOM 1178 O O   . THR A 1 284 ? 113.480 156.255 94.858  1.00 154.13 ? 284 THR A O   1 
ATOM 1179 C CB  . THR A 1 284 ? 115.413 157.634 96.819  1.00 154.36 ? 284 THR A CB  1 
ATOM 1180 O OG1 . THR A 1 284 ? 116.300 158.340 95.943  1.00 153.67 ? 284 THR A OG1 1 
ATOM 1181 C CG2 . THR A 1 284 ? 115.937 157.728 98.244  1.00 153.26 ? 284 THR A CG2 1 
ATOM 1182 N N   . ILE A 1 285 ? 115.507 155.859 93.954  1.00 147.75 ? 285 ILE A N   1 
ATOM 1183 C CA  . ILE A 1 285 ? 114.961 155.691 92.610  1.00 147.52 ? 285 ILE A CA  1 
ATOM 1184 C C   . ILE A 1 285 ? 114.077 154.453 92.552  1.00 146.42 ? 285 ILE A C   1 
ATOM 1185 O O   . ILE A 1 285 ? 112.981 154.476 91.978  1.00 146.25 ? 285 ILE A O   1 
ATOM 1186 C CB  . ILE A 1 285 ? 116.099 155.627 91.575  1.00 146.60 ? 285 ILE A CB  1 
ATOM 1187 C CG1 . ILE A 1 285 ? 116.924 156.915 91.610  1.00 146.07 ? 285 ILE A CG1 1 
ATOM 1188 C CG2 . ILE A 1 285 ? 115.540 155.387 90.180  1.00 144.73 ? 285 ILE A CG2 1 
ATOM 1189 C CD1 . ILE A 1 285 ? 118.042 156.954 90.592  1.00 146.98 ? 285 ILE A CD1 1 
ATOM 1190 N N   . CYS A 1 286 ? 114.540 153.354 93.149  1.00 146.99 ? 286 CYS A N   1 
ATOM 1191 C CA  . CYS A 1 286 ? 113.775 152.113 93.159  1.00 147.95 ? 286 CYS A CA  1 
ATOM 1192 C C   . CYS A 1 286 ? 112.699 152.126 94.239  1.00 148.55 ? 286 CYS A C   1 
ATOM 1193 O O   . CYS A 1 286 ? 111.541 151.784 93.975  1.00 150.32 ? 286 CYS A O   1 
ATOM 1194 C CB  . CYS A 1 286 ? 114.714 150.921 93.352  1.00 147.95 ? 286 CYS A CB  1 
ATOM 1195 S SG  . CYS A 1 286 ? 113.893 149.311 93.323  1.00 147.85 ? 286 CYS A SG  1 
ATOM 1196 N N   . TYR A 1 287 ? 113.058 152.520 95.458  1.00 146.74 ? 287 TYR A N   1 
ATOM 1197 C CA  . TYR A 1 287 ? 112.119 152.541 96.580  1.00 147.80 ? 287 TYR A CA  1 
ATOM 1198 C C   . TYR A 1 287 ? 111.890 153.972 97.041  1.00 147.67 ? 287 TYR A C   1 
ATOM 1199 O O   . TYR A 1 287 ? 112.712 154.526 97.794  1.00 147.41 ? 287 TYR A O   1 
ATOM 1200 C CB  . TYR A 1 287 ? 112.644 151.691 97.737  1.00 146.60 ? 287 TYR A CB  1 
ATOM 1201 C CG  . TYR A 1 287 ? 112.837 150.232 97.398  1.00 147.14 ? 287 TYR A CG  1 
ATOM 1202 C CD1 . TYR A 1 287 ? 111.769 149.345 97.420  1.00 146.79 ? 287 TYR A CD1 1 
ATOM 1203 C CD2 . TYR A 1 287 ? 114.092 149.739 97.064  1.00 147.35 ? 287 TYR A CD2 1 
ATOM 1204 C CE1 . TYR A 1 287 ? 111.944 148.008 97.113  1.00 146.75 ? 287 TYR A CE1 1 
ATOM 1205 C CE2 . TYR A 1 287 ? 114.278 148.405 96.757  1.00 147.52 ? 287 TYR A CE2 1 
ATOM 1206 C CZ  . TYR A 1 287 ? 113.201 147.545 96.782  1.00 147.40 ? 287 TYR A CZ  1 
ATOM 1207 O OH  . TYR A 1 287 ? 113.382 146.216 96.477  1.00 147.15 ? 287 TYR A OH  1 
ATOM 1208 N N   . PRO A 1 288 ? 110.802 154.616 96.613  1.00 148.71 ? 288 PRO A N   1 
ATOM 1209 C CA  . PRO A 1 288 ? 110.514 155.974 97.100  1.00 148.28 ? 288 PRO A CA  1 
ATOM 1210 C C   . PRO A 1 288 ? 110.306 156.056 98.603  1.00 148.78 ? 288 PRO A C   1 
ATOM 1211 O O   . PRO A 1 288 ? 110.656 157.075 99.212  1.00 147.46 ? 288 PRO A O   1 
ATOM 1212 C CB  . PRO A 1 288 ? 109.247 156.352 96.324  1.00 147.59 ? 288 PRO A CB  1 
ATOM 1213 C CG  . PRO A 1 288 ? 108.563 155.047 96.097  1.00 146.58 ? 288 PRO A CG  1 
ATOM 1214 C CD  . PRO A 1 288 ? 109.676 154.057 95.843  1.00 147.95 ? 288 PRO A CD  1 
ATOM 1215 N N   . GLU A 1 289 ? 109.743 155.016 99.222  1.00 147.53 ? 289 GLU A N   1 
ATOM 1216 C CA  . GLU A 1 289 ? 109.484 155.040 100.657 1.00 146.11 ? 289 GLU A CA  1 
ATOM 1217 C C   . GLU A 1 289 ? 110.746 154.906 101.500 1.00 146.10 ? 289 GLU A C   1 
ATOM 1218 O O   . GLU A 1 289 ? 110.676 155.115 102.716 1.00 146.35 ? 289 GLU A O   1 
ATOM 1219 C CB  . GLU A 1 289 ? 108.501 153.928 101.028 1.00 143.76 ? 289 GLU A CB  1 
ATOM 1220 N N   . TYR A 1 290 ? 111.882 154.559 100.901 1.00 153.73 ? 290 TYR A N   1 
ATOM 1221 C CA  . TYR A 1 290 ? 113.112 154.423 101.667 1.00 154.66 ? 290 TYR A CA  1 
ATOM 1222 C C   . TYR A 1 290 ? 113.543 155.805 102.147 1.00 155.60 ? 290 TYR A C   1 
ATOM 1223 O O   . TYR A 1 290 ? 113.490 156.781 101.393 1.00 154.41 ? 290 TYR A O   1 
ATOM 1224 C CB  . TYR A 1 290 ? 114.191 153.764 100.808 1.00 154.81 ? 290 TYR A CB  1 
ATOM 1225 C CG  . TYR A 1 290 ? 115.575 153.750 101.408 1.00 154.60 ? 290 TYR A CG  1 
ATOM 1226 C CD1 . TYR A 1 290 ? 115.891 152.862 102.427 1.00 153.42 ? 290 TYR A CD1 1 
ATOM 1227 C CD2 . TYR A 1 290 ? 116.573 154.591 100.938 1.00 153.21 ? 290 TYR A CD2 1 
ATOM 1228 C CE1 . TYR A 1 290 ? 117.151 152.826 102.977 1.00 153.18 ? 290 TYR A CE1 1 
ATOM 1229 C CE2 . TYR A 1 290 ? 117.843 154.561 101.483 1.00 153.19 ? 290 TYR A CE2 1 
ATOM 1230 C CZ  . TYR A 1 290 ? 118.124 153.674 102.502 1.00 154.13 ? 290 TYR A CZ  1 
ATOM 1231 O OH  . TYR A 1 290 ? 119.380 153.630 103.055 1.00 154.59 ? 290 TYR A OH  1 
ATOM 1232 N N   . ALA A 1 291 ? 113.971 155.896 103.405 1.00 158.92 ? 291 ALA A N   1 
ATOM 1233 C CA  . ALA A 1 291 ? 114.383 157.182 103.968 1.00 158.53 ? 291 ALA A CA  1 
ATOM 1234 C C   . ALA A 1 291 ? 115.675 157.076 104.774 1.00 157.93 ? 291 ALA A C   1 
ATOM 1235 O O   . ALA A 1 291 ? 115.783 157.603 105.882 1.00 157.78 ? 291 ALA A O   1 
ATOM 1236 C CB  . ALA A 1 291 ? 113.263 157.767 104.825 1.00 157.17 ? 291 ALA A CB  1 
ATOM 1237 N N   . GLY A 1 292 ? 116.679 156.391 104.235 1.00 157.27 ? 292 GLY A N   1 
ATOM 1238 C CA  . GLY A 1 292 ? 117.695 155.816 105.094 1.00 157.27 ? 292 GLY A CA  1 
ATOM 1239 C C   . GLY A 1 292 ? 119.096 156.193 104.656 1.00 157.83 ? 292 GLY A C   1 
ATOM 1240 O O   . GLY A 1 292 ? 119.263 156.996 103.733 1.00 157.23 ? 292 GLY A O   1 
ATOM 1241 N N   . SER A 1 293 ? 120.110 155.629 105.307 1.00 157.42 ? 293 SER A N   1 
ATOM 1242 C CA  . SER A 1 293 ? 121.489 155.954 104.969 1.00 156.93 ? 293 SER A CA  1 
ATOM 1243 C C   . SER A 1 293 ? 121.851 155.433 103.583 1.00 157.76 ? 293 SER A C   1 
ATOM 1244 O O   . SER A 1 293 ? 121.355 154.398 103.132 1.00 158.58 ? 293 SER A O   1 
ATOM 1245 C CB  . SER A 1 293 ? 122.447 155.382 106.013 1.00 156.85 ? 293 SER A CB  1 
ATOM 1246 O OG  . SER A 1 293 ? 122.404 153.968 106.026 1.00 157.74 ? 293 SER A OG  1 
ATOM 1247 N N   . ASN A 1 294 ? 122.740 156.158 102.912 1.00 156.18 ? 294 ASN A N   1 
ATOM 1248 C CA  . ASN A 1 294 ? 123.226 155.765 101.589 1.00 156.05 ? 294 ASN A CA  1 
ATOM 1249 C C   . ASN A 1 294 ? 124.431 154.832 101.691 1.00 155.98 ? 294 ASN A C   1 
ATOM 1250 O O   . ASN A 1 294 ? 125.494 155.092 101.130 1.00 156.26 ? 294 ASN A O   1 
ATOM 1251 C CB  . ASN A 1 294 ? 123.558 157.008 100.770 1.00 157.30 ? 294 ASN A CB  1 
ATOM 1252 C CG  . ASN A 1 294 ? 123.768 156.699 99.300  1.00 157.04 ? 294 ASN A CG  1 
ATOM 1253 O OD1 . ASN A 1 294 ? 122.821 156.697 98.513  1.00 156.32 ? 294 ASN A OD1 1 
ATOM 1254 N ND2 . ASN A 1 294 ? 125.013 156.435 98.923  1.00 156.19 ? 294 ASN A ND2 1 
ATOM 1255 N N   . THR A 1 295 ? 124.272 153.730 102.421 1.00 154.65 ? 295 THR A N   1 
ATOM 1256 C CA  . THR A 1 295 ? 125.350 152.775 102.630 1.00 154.40 ? 295 THR A CA  1 
ATOM 1257 C C   . THR A 1 295 ? 124.846 151.361 102.376 1.00 154.50 ? 295 THR A C   1 
ATOM 1258 O O   . THR A 1 295 ? 123.648 151.077 102.466 1.00 153.79 ? 295 THR A O   1 
ATOM 1259 C CB  . THR A 1 295 ? 125.931 152.869 104.050 1.00 153.82 ? 295 THR A CB  1 
ATOM 1260 O OG1 . THR A 1 295 ? 124.896 152.622 105.010 1.00 153.81 ? 295 THR A OG1 1 
ATOM 1261 C CG2 . THR A 1 295 ? 126.535 154.244 104.299 1.00 152.82 ? 295 THR A CG2 1 
ATOM 1262 N N   . TYR A 1 296 ? 125.789 150.474 102.049 1.00 152.82 ? 296 TYR A N   1 
ATOM 1263 C CA  . TYR A 1 296 ? 125.446 149.086 101.756 1.00 152.77 ? 296 TYR A CA  1 
ATOM 1264 C C   . TYR A 1 296 ? 124.852 148.384 102.973 1.00 151.77 ? 296 TYR A C   1 
ATOM 1265 O O   . TYR A 1 296 ? 123.874 147.638 102.851 1.00 151.05 ? 296 TYR A O   1 
ATOM 1266 C CB  . TYR A 1 296 ? 126.681 148.339 101.251 1.00 152.69 ? 296 TYR A CB  1 
ATOM 1267 C CG  . TYR A 1 296 ? 126.655 146.848 101.505 1.00 152.31 ? 296 TYR A CG  1 
ATOM 1268 C CD1 . TYR A 1 296 ? 125.888 146.002 100.714 1.00 152.33 ? 296 TYR A CD1 1 
ATOM 1269 C CD2 . TYR A 1 296 ? 127.405 146.285 102.529 1.00 151.81 ? 296 TYR A CD2 1 
ATOM 1270 C CE1 . TYR A 1 296 ? 125.863 144.639 100.941 1.00 152.35 ? 296 TYR A CE1 1 
ATOM 1271 C CE2 . TYR A 1 296 ? 127.387 144.923 102.763 1.00 151.83 ? 296 TYR A CE2 1 
ATOM 1272 C CZ  . TYR A 1 296 ? 126.615 144.105 101.966 1.00 152.31 ? 296 TYR A CZ  1 
ATOM 1273 O OH  . TYR A 1 296 ? 126.593 142.748 102.195 1.00 151.62 ? 296 TYR A OH  1 
ATOM 1274 N N   . GLU A 1 297 ? 125.433 148.607 104.155 1.00 153.21 ? 297 GLU A N   1 
ATOM 1275 C CA  . GLU A 1 297 ? 125.028 147.859 105.341 1.00 153.73 ? 297 GLU A CA  1 
ATOM 1276 C C   . GLU A 1 297 ? 123.589 148.137 105.757 1.00 153.75 ? 297 GLU A C   1 
ATOM 1277 O O   . GLU A 1 297 ? 123.012 147.344 106.508 1.00 153.57 ? 297 GLU A O   1 
ATOM 1278 C CB  . GLU A 1 297 ? 125.970 148.173 106.506 1.00 154.18 ? 297 GLU A CB  1 
ATOM 1279 C CG  . GLU A 1 297 ? 127.435 147.879 106.223 1.00 154.11 ? 297 GLU A CG  1 
ATOM 1280 C CD  . GLU A 1 297 ? 127.721 146.395 106.089 1.00 152.99 ? 297 GLU A CD  1 
ATOM 1281 O OE1 . GLU A 1 297 ? 126.922 145.582 106.601 1.00 153.70 ? 297 GLU A OE1 1 
ATOM 1282 O OE2 . GLU A 1 297 ? 128.748 146.040 105.473 1.00 152.00 ? 297 GLU A OE2 1 
ATOM 1283 N N   . GLU A 1 298 ? 122.996 149.234 105.293 1.00 148.71 ? 298 GLU A N   1 
ATOM 1284 C CA  . GLU A 1 298 ? 121.615 149.566 105.622 1.00 148.78 ? 298 GLU A CA  1 
ATOM 1285 C C   . GLU A 1 298 ? 120.665 149.462 104.441 1.00 148.22 ? 298 GLU A C   1 
ATOM 1286 O O   . GLU A 1 298 ? 119.508 149.075 104.623 1.00 146.63 ? 298 GLU A O   1 
ATOM 1287 C CB  . GLU A 1 298 ? 121.536 150.980 106.207 1.00 147.09 ? 298 GLU A CB  1 
ATOM 1288 N N   . ALA A 1 299 ? 121.115 149.801 103.231 1.00 143.40 ? 299 ALA A N   1 
ATOM 1289 C CA  . ALA A 1 299 ? 120.227 149.718 102.077 1.00 142.76 ? 299 ALA A CA  1 
ATOM 1290 C C   . ALA A 1 299 ? 119.985 148.271 101.669 1.00 141.86 ? 299 ALA A C   1 
ATOM 1291 O O   . ALA A 1 299 ? 118.868 147.907 101.284 1.00 140.40 ? 299 ALA A O   1 
ATOM 1292 C CB  . ALA A 1 299 ? 120.806 150.517 100.910 1.00 142.20 ? 299 ALA A CB  1 
ATOM 1293 N N   . ALA A 1 300 ? 121.023 147.433 101.738 1.00 138.41 ? 300 ALA A N   1 
ATOM 1294 C CA  . ALA A 1 300 ? 120.867 146.033 101.358 1.00 138.09 ? 300 ALA A CA  1 
ATOM 1295 C C   . ALA A 1 300 ? 119.921 145.307 102.305 1.00 137.87 ? 300 ALA A C   1 
ATOM 1296 O O   . ALA A 1 300 ? 119.100 144.492 101.869 1.00 139.63 ? 300 ALA A O   1 
ATOM 1297 C CB  . ALA A 1 300 ? 122.229 145.340 101.321 1.00 138.60 ? 300 ALA A CB  1 
ATOM 1298 N N   . ALA A 1 301 ? 120.029 145.584 103.608 1.00 131.76 ? 301 ALA A N   1 
ATOM 1299 C CA  . ALA A 1 301 ? 119.126 144.970 104.575 1.00 132.31 ? 301 ALA A CA  1 
ATOM 1300 C C   . ALA A 1 301 ? 117.684 145.404 104.354 1.00 131.33 ? 301 ALA A C   1 
ATOM 1301 O O   . ALA A 1 301 ? 116.756 144.633 104.628 1.00 129.54 ? 301 ALA A O   1 
ATOM 1302 C CB  . ALA A 1 301 ? 119.570 145.308 105.998 1.00 131.34 ? 301 ALA A CB  1 
ATOM 1303 N N   . TYR A 1 302 ? 117.472 146.631 103.872 1.00 137.89 ? 302 TYR A N   1 
ATOM 1304 C CA  . TYR A 1 302 ? 116.115 147.073 103.574 1.00 139.21 ? 302 TYR A CA  1 
ATOM 1305 C C   . TYR A 1 302 ? 115.535 146.284 102.407 1.00 140.07 ? 302 TYR A C   1 
ATOM 1306 O O   . TYR A 1 302 ? 114.365 145.886 102.438 1.00 139.88 ? 302 TYR A O   1 
ATOM 1307 C CB  . TYR A 1 302 ? 116.098 148.573 103.280 1.00 139.47 ? 302 TYR A CB  1 
ATOM 1308 C CG  . TYR A 1 302 ? 114.714 149.134 103.032 1.00 142.13 ? 302 TYR A CG  1 
ATOM 1309 C CD1 . TYR A 1 302 ? 113.886 149.478 104.093 1.00 140.61 ? 302 TYR A CD1 1 
ATOM 1310 C CD2 . TYR A 1 302 ? 114.236 149.320 101.742 1.00 142.24 ? 302 TYR A CD2 1 
ATOM 1311 C CE1 . TYR A 1 302 ? 112.621 149.991 103.878 1.00 139.84 ? 302 TYR A CE1 1 
ATOM 1312 C CE2 . TYR A 1 302 ? 112.970 149.833 101.517 1.00 141.47 ? 302 TYR A CE2 1 
ATOM 1313 C CZ  . TYR A 1 302 ? 112.168 150.166 102.589 1.00 141.19 ? 302 TYR A CZ  1 
ATOM 1314 O OH  . TYR A 1 302 ? 110.909 150.677 102.371 1.00 140.96 ? 302 TYR A OH  1 
ATOM 1315 N N   . ILE A 1 303 ? 116.342 146.048 101.370 1.00 130.91 ? 303 ILE A N   1 
ATOM 1316 C CA  . ILE A 1 303 ? 115.887 145.244 100.241 1.00 129.21 ? 303 ILE A CA  1 
ATOM 1317 C C   . ILE A 1 303 ? 115.678 143.800 100.675 1.00 126.98 ? 303 ILE A C   1 
ATOM 1318 O O   . ILE A 1 303 ? 114.725 143.139 100.245 1.00 125.83 ? 303 ILE A O   1 
ATOM 1319 C CB  . ILE A 1 303 ? 116.885 145.349 99.072  1.00 128.71 ? 303 ILE A CB  1 
ATOM 1320 C CG1 . ILE A 1 303 ? 117.089 146.812 98.674  1.00 129.56 ? 303 ILE A CG1 1 
ATOM 1321 C CG2 . ILE A 1 303 ? 116.403 144.538 97.880  1.00 128.31 ? 303 ILE A CG2 1 
ATOM 1322 C CD1 . ILE A 1 303 ? 118.020 147.001 97.496  1.00 129.41 ? 303 ILE A CD1 1 
ATOM 1323 N N   . GLN A 1 304 ? 116.570 143.286 101.527 1.00 119.18 ? 304 GLN A N   1 
ATOM 1324 C CA  . GLN A 1 304 ? 116.456 141.905 101.984 1.00 119.78 ? 304 GLN A CA  1 
ATOM 1325 C C   . GLN A 1 304 ? 115.152 141.684 102.737 1.00 121.08 ? 304 GLN A C   1 
ATOM 1326 O O   . GLN A 1 304 ? 114.464 140.679 102.524 1.00 123.20 ? 304 GLN A O   1 
ATOM 1327 C CB  . GLN A 1 304 ? 117.649 141.546 102.870 1.00 118.89 ? 304 GLN A CB  1 
ATOM 1328 C CG  . GLN A 1 304 ? 117.529 140.194 103.554 1.00 118.83 ? 304 GLN A CG  1 
ATOM 1329 C CD  . GLN A 1 304 ? 118.752 139.845 104.379 1.00 120.80 ? 304 GLN A CD  1 
ATOM 1330 O OE1 . GLN A 1 304 ? 119.704 140.620 104.456 1.00 124.23 ? 304 GLN A OE1 1 
ATOM 1331 N NE2 . GLN A 1 304 ? 118.730 138.673 105.002 1.00 120.01 ? 304 GLN A NE2 1 
ATOM 1332 N N   . CYS A 1 305 ? 114.795 142.617 103.622 1.00 124.48 ? 305 CYS A N   1 
ATOM 1333 C CA  . CYS A 1 305 ? 113.559 142.485 104.381 1.00 127.36 ? 305 CYS A CA  1 
ATOM 1334 C C   . CYS A 1 305 ? 112.330 142.771 103.530 1.00 127.60 ? 305 CYS A C   1 
ATOM 1335 O O   . CYS A 1 305 ? 111.236 142.316 103.876 1.00 125.35 ? 305 CYS A O   1 
ATOM 1336 C CB  . CYS A 1 305 ? 113.583 143.414 105.595 1.00 126.80 ? 305 CYS A CB  1 
ATOM 1337 S SG  . CYS A 1 305 ? 114.850 143.005 106.818 1.00 128.69 ? 305 CYS A SG  1 
ATOM 1338 N N   . GLN A 1 306 ? 112.483 143.519 102.434 1.00 128.31 ? 306 GLN A N   1 
ATOM 1339 C CA  . GLN A 1 306 ? 111.360 143.744 101.530 1.00 127.96 ? 306 GLN A CA  1 
ATOM 1340 C C   . GLN A 1 306 ? 110.910 142.444 100.877 1.00 127.71 ? 306 GLN A C   1 
ATOM 1341 O O   . GLN A 1 306 ? 109.707 142.185 100.755 1.00 127.64 ? 306 GLN A O   1 
ATOM 1342 C CB  . GLN A 1 306 ? 111.735 144.779 100.468 1.00 128.11 ? 306 GLN A CB  1 
ATOM 1343 C CG  . GLN A 1 306 ? 111.608 146.221 100.931 1.00 129.66 ? 306 GLN A CG  1 
ATOM 1344 C CD  . GLN A 1 306 ? 110.166 146.649 101.124 1.00 129.98 ? 306 GLN A CD  1 
ATOM 1345 O OE1 . GLN A 1 306 ? 109.243 146.010 100.617 1.00 131.39 ? 306 GLN A OE1 1 
ATOM 1346 N NE2 . GLN A 1 306 ? 109.964 147.734 101.862 1.00 127.65 ? 306 GLN A NE2 1 
ATOM 1347 N N   . PHE A 1 307 ? 111.864 141.616 100.444 1.00 117.39 ? 307 PHE A N   1 
ATOM 1348 C CA  . PHE A 1 307 ? 111.509 140.326 99.861  1.00 117.61 ? 307 PHE A CA  1 
ATOM 1349 C C   . PHE A 1 307 ? 110.918 139.394 100.911 1.00 117.80 ? 307 PHE A C   1 
ATOM 1350 O O   . PHE A 1 307 ? 109.910 138.724 100.658 1.00 115.89 ? 307 PHE A O   1 
ATOM 1351 C CB  . PHE A 1 307 ? 112.731 139.692 99.200  1.00 117.42 ? 307 PHE A CB  1 
ATOM 1352 C CG  . PHE A 1 307 ? 113.060 140.269 97.855  1.00 118.01 ? 307 PHE A CG  1 
ATOM 1353 C CD1 . PHE A 1 307 ? 113.876 141.382 97.743  1.00 118.22 ? 307 PHE A CD1 1 
ATOM 1354 C CD2 . PHE A 1 307 ? 112.549 139.701 96.700  1.00 116.67 ? 307 PHE A CD2 1 
ATOM 1355 C CE1 . PHE A 1 307 ? 114.178 141.915 96.506  1.00 116.99 ? 307 PHE A CE1 1 
ATOM 1356 C CE2 . PHE A 1 307 ? 112.848 140.230 95.461  1.00 116.12 ? 307 PHE A CE2 1 
ATOM 1357 C CZ  . PHE A 1 307 ? 113.663 141.337 95.364  1.00 116.04 ? 307 PHE A CZ  1 
ATOM 1358 N N   . GLU A 1 308 ? 111.539 139.330 102.093 1.00 111.38 ? 308 GLU A N   1 
ATOM 1359 C CA  . GLU A 1 308 ? 111.000 138.494 103.160 1.00 110.05 ? 308 GLU A CA  1 
ATOM 1360 C C   . GLU A 1 308 ? 109.648 139.010 103.637 1.00 110.49 ? 308 GLU A C   1 
ATOM 1361 O O   . GLU A 1 308 ? 108.843 138.237 104.169 1.00 110.82 ? 308 GLU A O   1 
ATOM 1362 C CB  . GLU A 1 308 ? 111.990 138.421 104.322 1.00 111.96 ? 308 GLU A CB  1 
ATOM 1363 C CG  . GLU A 1 308 ? 113.333 137.810 103.951 1.00 109.83 ? 308 GLU A CG  1 
ATOM 1364 C CD  . GLU A 1 308 ? 114.259 137.666 105.143 1.00 113.54 ? 308 GLU A CD  1 
ATOM 1365 O OE1 . GLU A 1 308 ? 113.844 138.020 106.266 1.00 115.15 ? 308 GLU A OE1 1 
ATOM 1366 O OE2 . GLU A 1 308 ? 115.402 137.197 104.957 1.00 112.04 ? 308 GLU A OE2 1 
ATOM 1367 N N   . ASP A 1 309 ? 109.387 140.308 103.461 1.00 118.49 ? 309 ASP A N   1 
ATOM 1368 C CA  . ASP A 1 309 ? 108.085 140.871 103.796 1.00 120.50 ? 309 ASP A CA  1 
ATOM 1369 C C   . ASP A 1 309 ? 106.993 140.372 102.861 1.00 119.80 ? 309 ASP A C   1 
ATOM 1370 O O   . ASP A 1 309 ? 105.819 140.363 103.246 1.00 119.73 ? 309 ASP A O   1 
ATOM 1371 C CB  . ASP A 1 309 ? 108.141 142.400 103.763 1.00 118.22 ? 309 ASP A CB  1 
ATOM 1372 C CG  . ASP A 1 309 ? 106.837 143.041 104.193 1.00 120.72 ? 309 ASP A CG  1 
ATOM 1373 O OD1 . ASP A 1 309 ? 106.506 142.964 105.395 1.00 121.60 ? 309 ASP A OD1 1 
ATOM 1374 O OD2 . ASP A 1 309 ? 106.144 143.623 103.332 1.00 121.75 ? 309 ASP A OD2 1 
ATOM 1375 N N   . LEU A 1 310 ? 107.354 139.952 101.646 1.00 105.94 ? 310 LEU A N   1 
ATOM 1376 C CA  . LEU A 1 310 ? 106.371 139.447 100.698 1.00 104.40 ? 310 LEU A CA  1 
ATOM 1377 C C   . LEU A 1 310 ? 105.800 138.096 101.107 1.00 104.41 ? 310 LEU A C   1 
ATOM 1378 O O   . LEU A 1 310 ? 104.841 137.636 100.479 1.00 106.34 ? 310 LEU A O   1 
ATOM 1379 C CB  . LEU A 1 310 ? 106.995 139.338 99.304  1.00 104.97 ? 310 LEU A CB  1 
ATOM 1380 C CG  . LEU A 1 310 ? 107.636 140.602 98.728  1.00 105.95 ? 310 LEU A CG  1 
ATOM 1381 C CD1 . LEU A 1 310 ? 108.230 140.320 97.357  1.00 103.37 ? 310 LEU A CD1 1 
ATOM 1382 C CD2 . LEU A 1 310 ? 106.622 141.731 98.650  1.00 106.72 ? 310 LEU A CD2 1 
ATOM 1383 N N   . ASN A 1 311 ? 106.364 137.453 102.129 1.00 93.62  ? 311 ASN A N   1 
ATOM 1384 C CA  . ASN A 1 311 ? 105.828 136.191 102.621 1.00 93.23  ? 311 ASN A CA  1 
ATOM 1385 C C   . ASN A 1 311 ? 104.438 136.414 103.201 1.00 97.11  ? 311 ASN A C   1 
ATOM 1386 O O   . ASN A 1 311 ? 104.296 136.990 104.284 1.00 99.68  ? 311 ASN A O   1 
ATOM 1387 C CB  . ASN A 1 311 ? 106.752 135.575 103.673 1.00 91.21  ? 311 ASN A CB  1 
ATOM 1388 C CG  . ASN A 1 311 ? 106.613 134.067 103.758 1.00 91.83  ? 311 ASN A CG  1 
ATOM 1389 O OD1 . ASN A 1 311 ? 105.505 133.533 103.715 1.00 93.85  ? 311 ASN A OD1 1 
ATOM 1390 N ND2 . ASN A 1 311 ? 107.736 133.374 103.895 1.00 94.61  ? 311 ASN A ND2 1 
ATOM 1391 N N   . LYS A 1 312 ? 103.406 135.968 102.486 1.00 107.45 ? 312 LYS A N   1 
ATOM 1392 C CA  . LYS A 1 312 ? 102.037 136.148 102.946 1.00 111.29 ? 312 LYS A CA  1 
ATOM 1393 C C   . LYS A 1 312 ? 101.640 135.146 104.021 1.00 111.60 ? 312 LYS A C   1 
ATOM 1394 O O   . LYS A 1 312 ? 100.588 135.316 104.646 1.00 113.28 ? 312 LYS A O   1 
ATOM 1395 C CB  . LYS A 1 312 ? 101.073 136.041 101.762 1.00 110.10 ? 312 LYS A CB  1 
ATOM 1396 C CG  . LYS A 1 312 ? 99.818  136.888 101.895 1.00 111.50 ? 312 LYS A CG  1 
ATOM 1397 C CD  . LYS A 1 312 ? 100.155 138.369 101.867 1.00 109.60 ? 312 LYS A CD  1 
ATOM 1398 C CE  . LYS A 1 312 ? 100.847 138.753 100.568 1.00 111.09 ? 312 LYS A CE  1 
ATOM 1399 N NZ  . LYS A 1 312 ? 101.217 140.195 100.539 1.00 110.38 ? 312 LYS A NZ  1 
ATOM 1400 N N   . ARG A 1 313 ? 102.455 134.116 104.252 1.00 108.51 ? 313 ARG A N   1 
ATOM 1401 C CA  . ARG A 1 313 ? 102.185 133.088 105.262 1.00 109.73 ? 313 ARG A CA  1 
ATOM 1402 C C   . ARG A 1 313 ? 103.491 132.819 106.009 1.00 109.09 ? 313 ARG A C   1 
ATOM 1403 O O   . ARG A 1 313 ? 104.260 131.928 105.639 1.00 110.71 ? 313 ARG A O   1 
ATOM 1404 C CB  . ARG A 1 313 ? 101.614 131.827 104.627 1.00 107.34 ? 313 ARG A CB  1 
ATOM 1405 C CG  . ARG A 1 313 ? 102.246 131.452 103.293 1.00 107.52 ? 313 ARG A CG  1 
ATOM 1406 C CD  . ARG A 1 313 ? 101.349 130.511 102.508 1.00 109.59 ? 313 ARG A CD  1 
ATOM 1407 N NE  . ARG A 1 313 ? 100.080 131.138 102.161 1.00 111.75 ? 313 ARG A NE  1 
ATOM 1408 C CZ  . ARG A 1 313 ? 99.133  130.563 101.432 1.00 109.98 ? 313 ARG A CZ  1 
ATOM 1409 N NH1 . ARG A 1 313 ? 99.279  129.339 100.950 1.00 107.91 ? 313 ARG A NH1 1 
ATOM 1410 N NH2 . ARG A 1 313 ? 98.013  131.233 101.179 1.00 107.50 ? 313 ARG A NH2 1 
ATOM 1411 N N   . LYS A 1 314 ? 103.735 133.590 107.071 1.00 97.02  ? 314 LYS A N   1 
ATOM 1412 C CA  . LYS A 1 314 ? 104.942 133.431 107.871 1.00 97.70  ? 314 LYS A CA  1 
ATOM 1413 C C   . LYS A 1 314 ? 104.832 132.314 108.899 1.00 100.31 ? 314 LYS A C   1 
ATOM 1414 O O   . LYS A 1 314 ? 105.641 132.264 109.833 1.00 103.74 ? 314 LYS A O   1 
ATOM 1415 C CB  . LYS A 1 314 ? 105.286 134.745 108.579 1.00 96.68  ? 314 LYS A CB  1 
ATOM 1416 C CG  . LYS A 1 314 ? 105.703 135.873 107.653 1.00 96.32  ? 314 LYS A CG  1 
ATOM 1417 C CD  . LYS A 1 314 ? 106.002 137.136 108.444 1.00 93.89  ? 314 LYS A CD  1 
ATOM 1418 C CE  . LYS A 1 314 ? 106.444 138.270 107.536 1.00 97.55  ? 314 LYS A CE  1 
ATOM 1419 N NZ  . LYS A 1 314 ? 106.714 139.516 108.306 1.00 99.09  ? 314 LYS A NZ  1 
ATOM 1420 N N   . ASP A 1 315 ? 103.857 131.421 108.751 1.00 92.81  ? 315 ASP A N   1 
ATOM 1421 C CA  . ASP A 1 315 ? 103.657 130.314 109.674 1.00 90.00  ? 315 ASP A CA  1 
ATOM 1422 C C   . ASP A 1 315 ? 104.022 128.970 109.065 1.00 89.72  ? 315 ASP A C   1 
ATOM 1423 O O   . ASP A 1 315 ? 104.719 128.171 109.698 1.00 87.76  ? 315 ASP A O   1 
ATOM 1424 C CB  . ASP A 1 315 ? 102.198 130.290 110.154 1.00 93.41  ? 315 ASP A CB  1 
ATOM 1425 C CG  . ASP A 1 315 ? 101.762 131.613 110.753 1.00 94.80  ? 315 ASP A CG  1 
ATOM 1426 O OD1 . ASP A 1 315 ? 101.635 132.597 109.993 1.00 96.26  ? 315 ASP A OD1 1 
ATOM 1427 O OD2 . ASP A 1 315 ? 101.548 131.671 111.982 1.00 94.80  ? 315 ASP A OD2 1 
ATOM 1428 N N   . THR A 1 316 ? 103.570 128.700 107.841 1.00 90.48  ? 316 THR A N   1 
ATOM 1429 C CA  . THR A 1 316 ? 103.773 127.400 107.219 1.00 90.95  ? 316 THR A CA  1 
ATOM 1430 C C   . THR A 1 316 ? 105.058 127.309 106.405 1.00 91.02  ? 316 THR A C   1 
ATOM 1431 O O   . THR A 1 316 ? 105.399 126.214 105.945 1.00 96.47  ? 316 THR A O   1 
ATOM 1432 C CB  . THR A 1 316 ? 102.582 127.054 106.318 1.00 91.27  ? 316 THR A CB  1 
ATOM 1433 O OG1 . THR A 1 316 ? 102.451 128.047 105.294 1.00 94.16  ? 316 THR A OG1 1 
ATOM 1434 C CG2 . THR A 1 316 ? 101.298 127.005 107.132 1.00 87.89  ? 316 THR A CG2 1 
ATOM 1435 N N   . LYS A 1 317 ? 105.777 128.413 106.212 1.00 76.18  ? 317 LYS A N   1 
ATOM 1436 C CA  . LYS A 1 317 ? 106.993 128.376 105.411 1.00 71.24  ? 317 LYS A CA  1 
ATOM 1437 C C   . LYS A 1 317 ? 107.979 129.416 105.921 1.00 76.43  ? 317 LYS A C   1 
ATOM 1438 O O   . LYS A 1 317 ? 107.607 130.383 106.592 1.00 80.22  ? 317 LYS A O   1 
ATOM 1439 C CB  . LYS A 1 317 ? 106.694 128.622 103.928 1.00 70.85  ? 317 LYS A CB  1 
ATOM 1440 C CG  . LYS A 1 317 ? 106.589 130.092 103.556 1.00 70.73  ? 317 LYS A CG  1 
ATOM 1441 C CD  . LYS A 1 317 ? 106.413 130.267 102.061 1.00 72.64  ? 317 LYS A CD  1 
ATOM 1442 C CE  . LYS A 1 317 ? 105.078 129.711 101.609 1.00 69.01  ? 317 LYS A CE  1 
ATOM 1443 N NZ  . LYS A 1 317 ? 104.946 129.688 100.129 1.00 74.97  ? 317 LYS A NZ  1 
ATOM 1444 N N   . GLU A 1 318 ? 109.250 129.199 105.597 1.00 70.41  ? 318 GLU A N   1 
ATOM 1445 C CA  . GLU A 1 318 ? 110.320 130.131 105.915 1.00 69.51  ? 318 GLU A CA  1 
ATOM 1446 C C   . GLU A 1 318 ? 111.066 130.520 104.644 1.00 71.30  ? 318 GLU A C   1 
ATOM 1447 O O   . GLU A 1 318 ? 111.030 129.811 103.636 1.00 73.25  ? 318 GLU A O   1 
ATOM 1448 C CB  . GLU A 1 318 ? 111.297 129.539 106.942 1.00 71.50  ? 318 GLU A CB  1 
ATOM 1449 C CG  . GLU A 1 318 ? 111.588 128.058 106.767 1.00 71.34  ? 318 GLU A CG  1 
ATOM 1450 C CD  . GLU A 1 318 ? 110.564 127.177 107.455 1.00 75.84  ? 318 GLU A CD  1 
ATOM 1451 O OE1 . GLU A 1 318 ? 109.674 127.723 108.142 1.00 78.77  ? 318 GLU A OE1 1 
ATOM 1452 O OE2 . GLU A 1 318 ? 110.650 125.941 107.312 1.00 73.45  ? 318 GLU A OE2 1 
ATOM 1453 N N   . ILE A 1 319 ? 111.746 131.663 104.705 1.00 71.80  ? 319 ILE A N   1 
ATOM 1454 C CA  . ILE A 1 319 ? 112.579 132.157 103.612 1.00 65.91  ? 319 ILE A CA  1 
ATOM 1455 C C   . ILE A 1 319 ? 114.016 132.232 104.107 1.00 67.39  ? 319 ILE A C   1 
ATOM 1456 O O   . ILE A 1 319 ? 114.300 132.910 105.102 1.00 75.06  ? 319 ILE A O   1 
ATOM 1457 C CB  . ILE A 1 319 ? 112.107 133.525 103.095 1.00 66.97  ? 319 ILE A CB  1 
ATOM 1458 C CG1 . ILE A 1 319 ? 110.732 133.409 102.439 1.00 62.40  ? 319 ILE A CG1 1 
ATOM 1459 C CG2 . ILE A 1 319 ? 113.115 134.102 102.117 1.00 72.38  ? 319 ILE A CG2 1 
ATOM 1460 C CD1 . ILE A 1 319 ? 110.093 134.748 102.138 1.00 73.72  ? 319 ILE A CD1 1 
ATOM 1461 N N   . TYR A 1 320 ? 114.918 131.538 103.418 1.00 51.69  ? 320 TYR A N   1 
ATOM 1462 C CA  . TYR A 1 320 ? 116.340 131.562 103.737 1.00 53.04  ? 320 TYR A CA  1 
ATOM 1463 C C   . TYR A 1 320 ? 117.050 132.499 102.767 1.00 64.60  ? 320 TYR A C   1 
ATOM 1464 O O   . TYR A 1 320 ? 117.020 132.279 101.551 1.00 73.80  ? 320 TYR A O   1 
ATOM 1465 C CB  . TYR A 1 320 ? 116.939 130.157 103.673 1.00 50.25  ? 320 TYR A CB  1 
ATOM 1466 C CG  . TYR A 1 320 ? 116.258 129.155 104.578 1.00 57.84  ? 320 TYR A CG  1 
ATOM 1467 C CD1 . TYR A 1 320 ? 116.660 128.999 105.896 1.00 64.30  ? 320 TYR A CD1 1 
ATOM 1468 C CD2 . TYR A 1 320 ? 115.218 128.362 104.115 1.00 61.69  ? 320 TYR A CD2 1 
ATOM 1469 C CE1 . TYR A 1 320 ? 116.046 128.084 106.728 1.00 59.56  ? 320 TYR A CE1 1 
ATOM 1470 C CE2 . TYR A 1 320 ? 114.596 127.445 104.942 1.00 57.10  ? 320 TYR A CE2 1 
ATOM 1471 C CZ  . TYR A 1 320 ? 115.015 127.310 106.246 1.00 55.74  ? 320 TYR A CZ  1 
ATOM 1472 O OH  . TYR A 1 320 ? 114.398 126.398 107.072 1.00 65.00  ? 320 TYR A OH  1 
ATOM 1473 N N   . THR A 1 321 ? 117.682 133.538 103.305 1.00 82.73  ? 321 THR A N   1 
ATOM 1474 C CA  . THR A 1 321 ? 118.325 134.579 102.513 1.00 84.32  ? 321 THR A CA  1 
ATOM 1475 C C   . THR A 1 321 ? 119.836 134.498 102.691 1.00 84.38  ? 321 THR A C   1 
ATOM 1476 O O   . THR A 1 321 ? 120.326 134.384 103.819 1.00 88.37  ? 321 THR A O   1 
ATOM 1477 C CB  . THR A 1 321 ? 117.819 135.966 102.915 1.00 85.52  ? 321 THR A CB  1 
ATOM 1478 O OG1 . THR A 1 321 ? 116.391 136.005 102.805 1.00 84.68  ? 321 THR A OG1 1 
ATOM 1479 C CG2 . THR A 1 321 ? 118.415 137.030 102.007 1.00 85.49  ? 321 THR A CG2 1 
ATOM 1480 N N   . HIS A 1 322 ? 120.568 134.557 101.579 1.00 85.45  ? 322 HIS A N   1 
ATOM 1481 C CA  . HIS A 1 322 ? 122.019 134.450 101.594 1.00 86.28  ? 322 HIS A CA  1 
ATOM 1482 C C   . HIS A 1 322 ? 122.607 135.466 100.626 1.00 93.97  ? 322 HIS A C   1 
ATOM 1483 O O   . HIS A 1 322 ? 121.976 135.839 99.634  1.00 97.25  ? 322 HIS A O   1 
ATOM 1484 C CB  . HIS A 1 322 ? 122.487 133.042 101.215 1.00 84.81  ? 322 HIS A CB  1 
ATOM 1485 C CG  . HIS A 1 322 ? 123.968 132.849 101.309 1.00 89.90  ? 322 HIS A CG  1 
ATOM 1486 N ND1 . HIS A 1 322 ? 124.669 133.040 102.480 1.00 90.78  ? 322 HIS A ND1 1 
ATOM 1487 C CD2 . HIS A 1 322 ? 124.881 132.478 100.381 1.00 93.50  ? 322 HIS A CD2 1 
ATOM 1488 C CE1 . HIS A 1 322 ? 125.950 132.796 102.269 1.00 94.55  ? 322 HIS A CE1 1 
ATOM 1489 N NE2 . HIS A 1 322 ? 126.105 132.454 101.003 1.00 94.41  ? 322 HIS A NE2 1 
ATOM 1490 N N   . PHE A 1 323 ? 123.826 135.910 100.925 1.00 106.38 ? 323 PHE A N   1 
ATOM 1491 C CA  . PHE A 1 323 ? 124.547 136.873 100.099 1.00 107.55 ? 323 PHE A CA  1 
ATOM 1492 C C   . PHE A 1 323 ? 125.690 136.151 99.394  1.00 108.63 ? 323 PHE A C   1 
ATOM 1493 O O   . PHE A 1 323 ? 126.667 135.747 100.034 1.00 108.91 ? 323 PHE A O   1 
ATOM 1494 C CB  . PHE A 1 323 ? 125.070 138.035 100.940 1.00 107.94 ? 323 PHE A CB  1 
ATOM 1495 C CG  . PHE A 1 323 ? 123.993 138.950 101.445 1.00 108.85 ? 323 PHE A CG  1 
ATOM 1496 C CD1 . PHE A 1 323 ? 123.502 139.970 100.646 1.00 107.98 ? 323 PHE A CD1 1 
ATOM 1497 C CD2 . PHE A 1 323 ? 123.476 138.797 102.719 1.00 108.36 ? 323 PHE A CD2 1 
ATOM 1498 C CE1 . PHE A 1 323 ? 122.514 140.815 101.106 1.00 106.11 ? 323 PHE A CE1 1 
ATOM 1499 C CE2 . PHE A 1 323 ? 122.488 139.640 103.186 1.00 109.31 ? 323 PHE A CE2 1 
ATOM 1500 C CZ  . PHE A 1 323 ? 122.006 140.651 102.378 1.00 107.48 ? 323 PHE A CZ  1 
ATOM 1501 N N   . THR A 1 324 ? 125.560 135.987 98.081  1.00 110.41 ? 324 THR A N   1 
ATOM 1502 C CA  . THR A 1 324 ? 126.556 135.317 97.264  1.00 111.03 ? 324 THR A CA  1 
ATOM 1503 C C   . THR A 1 324 ? 127.443 136.350 96.571  1.00 112.15 ? 324 THR A C   1 
ATOM 1504 O O   . THR A 1 324 ? 127.322 137.559 96.788  1.00 112.83 ? 324 THR A O   1 
ATOM 1505 C CB  . THR A 1 324 ? 125.879 134.404 96.238  1.00 112.85 ? 324 THR A CB  1 
ATOM 1506 O OG1 . THR A 1 324 ? 125.101 135.198 95.333  1.00 111.79 ? 324 THR A OG1 1 
ATOM 1507 C CG2 . THR A 1 324 ? 124.961 133.413 96.935  1.00 111.33 ? 324 THR A CG2 1 
ATOM 1508 N N   . CYS A 1 325 ? 128.342 135.862 95.721  1.00 123.84 ? 325 CYS A N   1 
ATOM 1509 C CA  . CYS A 1 325 ? 129.221 136.720 94.935  1.00 126.13 ? 325 CYS A CA  1 
ATOM 1510 C C   . CYS A 1 325 ? 129.835 135.882 93.820  1.00 125.22 ? 325 CYS A C   1 
ATOM 1511 O O   . CYS A 1 325 ? 129.568 134.684 93.697  1.00 123.90 ? 325 CYS A O   1 
ATOM 1512 C CB  . CYS A 1 325 ? 130.301 137.364 95.809  1.00 126.09 ? 325 CYS A CB  1 
ATOM 1513 S SG  . CYS A 1 325 ? 131.441 138.441 94.910  1.00 127.96 ? 325 CYS A SG  1 
ATOM 1514 N N   . SER A 1 326 ? 130.671 136.527 93.005  1.00 118.82 ? 326 SER A N   1 
ATOM 1515 C CA  . SER A 1 326 ? 131.308 135.847 91.885  1.00 118.54 ? 326 SER A CA  1 
ATOM 1516 C C   . SER A 1 326 ? 132.512 135.012 92.299  1.00 119.65 ? 326 SER A C   1 
ATOM 1517 O O   . SER A 1 326 ? 133.003 134.220 91.487  1.00 118.75 ? 326 SER A O   1 
ATOM 1518 C CB  . SER A 1 326 ? 131.732 136.867 90.825  1.00 116.67 ? 326 SER A CB  1 
ATOM 1519 O OG  . SER A 1 326 ? 130.615 137.596 90.346  1.00 114.53 ? 326 SER A OG  1 
ATOM 1520 N N   . THR A 1 327 ? 132.999 135.169 93.533  1.00 127.75 ? 327 THR A N   1 
ATOM 1521 C CA  . THR A 1 327 ? 134.163 134.432 94.012  1.00 127.50 ? 327 THR A CA  1 
ATOM 1522 C C   . THR A 1 327 ? 133.880 133.752 95.347  1.00 126.41 ? 327 THR A C   1 
ATOM 1523 O O   . THR A 1 327 ? 134.816 133.342 96.040  1.00 126.28 ? 327 THR A O   1 
ATOM 1524 C CB  . THR A 1 327 ? 135.381 135.352 94.141  1.00 127.56 ? 327 THR A CB  1 
ATOM 1525 O OG1 . THR A 1 327 ? 135.061 136.457 94.996  1.00 126.77 ? 327 THR A OG1 1 
ATOM 1526 C CG2 . THR A 1 327 ? 135.807 135.875 92.776  1.00 126.52 ? 327 THR A CG2 1 
ATOM 1527 N N   . ASP A 1 328 ? 132.609 133.627 95.717  1.00 121.00 ? 328 ASP A N   1 
ATOM 1528 C CA  . ASP A 1 328 ? 132.243 133.016 96.983  1.00 120.52 ? 328 ASP A CA  1 
ATOM 1529 C C   . ASP A 1 328 ? 132.432 131.502 96.932  1.00 119.82 ? 328 ASP A C   1 
ATOM 1530 O O   . ASP A 1 328 ? 132.436 130.878 95.867  1.00 118.37 ? 328 ASP A O   1 
ATOM 1531 C CB  . ASP A 1 328 ? 130.797 133.355 97.344  1.00 120.67 ? 328 ASP A CB  1 
ATOM 1532 C CG  . ASP A 1 328 ? 130.513 133.189 98.824  1.00 122.65 ? 328 ASP A CG  1 
ATOM 1533 O OD1 . ASP A 1 328 ? 131.445 132.829 99.573  1.00 123.38 ? 328 ASP A OD1 1 
ATOM 1534 O OD2 . ASP A 1 328 ? 129.359 133.422 99.240  1.00 121.86 ? 328 ASP A OD2 1 
ATOM 1535 N N   . THR A 1 329 ? 132.590 130.912 98.119  1.00 122.87 ? 329 THR A N   1 
ATOM 1536 C CA  . THR A 1 329 ? 132.700 129.468 98.270  1.00 122.93 ? 329 THR A CA  1 
ATOM 1537 C C   . THR A 1 329 ? 131.684 128.921 99.265  1.00 121.92 ? 329 THR A C   1 
ATOM 1538 O O   . THR A 1 329 ? 131.720 127.725 99.578  1.00 118.93 ? 329 THR A O   1 
ATOM 1539 C CB  . THR A 1 329 ? 134.118 129.071 98.703  1.00 123.92 ? 329 THR A CB  1 
ATOM 1540 O OG1 . THR A 1 329 ? 134.258 127.646 98.645  1.00 121.15 ? 329 THR A OG1 1 
ATOM 1541 C CG2 . THR A 1 329 ? 134.396 129.548 100.121 1.00 121.86 ? 329 THR A CG2 1 
ATOM 1542 N N   . LYS A 1 330 ? 130.779 129.763 99.765  1.00 112.61 ? 330 LYS A N   1 
ATOM 1543 C CA  . LYS A 1 330 ? 129.769 129.358 100.733 1.00 109.42 ? 330 LYS A CA  1 
ATOM 1544 C C   . LYS A 1 330 ? 128.368 129.335 100.133 1.00 108.39 ? 330 LYS A C   1 
ATOM 1545 O O   . LYS A 1 330 ? 127.381 129.318 100.875 1.00 111.33 ? 330 LYS A O   1 
ATOM 1546 C CB  . LYS A 1 330 ? 129.802 130.283 101.950 1.00 108.42 ? 330 LYS A CB  1 
ATOM 1547 C CG  . LYS A 1 330 ? 131.157 130.380 102.626 1.00 109.09 ? 330 LYS A CG  1 
ATOM 1548 C CD  . LYS A 1 330 ? 131.125 131.385 103.765 1.00 108.55 ? 330 LYS A CD  1 
ATOM 1549 C CE  . LYS A 1 330 ? 132.489 131.530 104.417 1.00 108.26 ? 330 LYS A CE  1 
ATOM 1550 N NZ  . LYS A 1 330 ? 132.467 132.526 105.524 1.00 108.24 ? 330 LYS A NZ  1 
ATOM 1551 N N   . ASN A 1 331 ? 128.258 129.339 98.803  1.00 102.74 ? 331 ASN A N   1 
ATOM 1552 C CA  . ASN A 1 331 ? 126.937 129.315 98.185  1.00 102.22 ? 331 ASN A CA  1 
ATOM 1553 C C   . ASN A 1 331 ? 126.303 127.935 98.304  1.00 104.26 ? 331 ASN A C   1 
ATOM 1554 O O   . ASN A 1 331 ? 125.105 127.817 98.585  1.00 106.28 ? 331 ASN A O   1 
ATOM 1555 C CB  . ASN A 1 331 ? 127.038 129.739 96.720  1.00 103.77 ? 331 ASN A CB  1 
ATOM 1556 C CG  . ASN A 1 331 ? 127.753 131.065 96.546  1.00 107.97 ? 331 ASN A CG  1 
ATOM 1557 O OD1 . ASN A 1 331 ? 127.753 131.906 97.445  1.00 107.98 ? 331 ASN A OD1 1 
ATOM 1558 N ND2 . ASN A 1 331 ? 128.369 131.258 95.385  1.00 107.68 ? 331 ASN A ND2 1 
ATOM 1559 N N   . VAL A 1 332 ? 127.092 126.880 98.089  1.00 91.35  ? 332 VAL A N   1 
ATOM 1560 C CA  . VAL A 1 332 ? 126.566 125.524 98.192  1.00 93.11  ? 332 VAL A CA  1 
ATOM 1561 C C   . VAL A 1 332 ? 126.338 125.148 99.651  1.00 93.16  ? 332 VAL A C   1 
ATOM 1562 O O   . VAL A 1 332 ? 125.423 124.378 99.967  1.00 92.64  ? 332 VAL A O   1 
ATOM 1563 C CB  . VAL A 1 332 ? 127.507 124.531 97.482  1.00 94.92  ? 332 VAL A CB  1 
ATOM 1564 C CG1 . VAL A 1 332 ? 128.901 124.576 98.093  1.00 91.74  ? 332 VAL A CG1 1 
ATOM 1565 C CG2 . VAL A 1 332 ? 126.939 123.119 97.529  1.00 97.16  ? 332 VAL A CG2 1 
ATOM 1566 N N   . GLN A 1 333 ? 127.152 125.690 100.562 1.00 82.94  ? 333 GLN A N   1 
ATOM 1567 C CA  . GLN A 1 333 ? 126.969 125.410 101.982 1.00 78.98  ? 333 GLN A CA  1 
ATOM 1568 C C   . GLN A 1 333 ? 125.641 125.955 102.489 1.00 78.38  ? 333 GLN A C   1 
ATOM 1569 O O   . GLN A 1 333 ? 124.963 125.305 103.294 1.00 84.72  ? 333 GLN A O   1 
ATOM 1570 C CB  . GLN A 1 333 ? 128.132 125.997 102.782 1.00 79.26  ? 333 GLN A CB  1 
ATOM 1571 C CG  . GLN A 1 333 ? 128.017 125.800 104.285 1.00 83.80  ? 333 GLN A CG  1 
ATOM 1572 C CD  . GLN A 1 333 ? 128.125 124.344 104.694 1.00 88.20  ? 333 GLN A CD  1 
ATOM 1573 O OE1 . GLN A 1 333 ? 128.773 123.543 104.020 1.00 87.67  ? 333 GLN A OE1 1 
ATOM 1574 N NE2 . GLN A 1 333 ? 127.489 123.994 105.806 1.00 85.80  ? 333 GLN A NE2 1 
ATOM 1575 N N   . PHE A 1 334 ? 125.256 127.153 102.040 1.00 69.64  ? 334 PHE A N   1 
ATOM 1576 C CA  . PHE A 1 334 ? 123.994 127.730 102.490 1.00 71.32  ? 334 PHE A CA  1 
ATOM 1577 C C   . PHE A 1 334 ? 122.811 126.887 102.033 1.00 78.61  ? 334 PHE A C   1 
ATOM 1578 O O   . PHE A 1 334 ? 121.860 126.673 102.794 1.00 83.95  ? 334 PHE A O   1 
ATOM 1579 C CB  . PHE A 1 334 ? 123.853 129.163 101.980 1.00 74.11  ? 334 PHE A CB  1 
ATOM 1580 C CG  . PHE A 1 334 ? 122.606 129.853 102.457 1.00 73.39  ? 334 PHE A CG  1 
ATOM 1581 C CD1 . PHE A 1 334 ? 122.605 130.552 103.650 1.00 76.00  ? 334 PHE A CD1 1 
ATOM 1582 C CD2 . PHE A 1 334 ? 121.433 129.792 101.721 1.00 74.30  ? 334 PHE A CD2 1 
ATOM 1583 C CE1 . PHE A 1 334 ? 121.464 131.189 104.096 1.00 78.11  ? 334 PHE A CE1 1 
ATOM 1584 C CE2 . PHE A 1 334 ? 120.288 130.424 102.166 1.00 73.63  ? 334 PHE A CE2 1 
ATOM 1585 C CZ  . PHE A 1 334 ? 120.305 131.123 103.354 1.00 73.83  ? 334 PHE A CZ  1 
ATOM 1586 N N   . VAL A 1 335 ? 122.849 126.405 100.789 1.00 71.58  ? 335 VAL A N   1 
ATOM 1587 C CA  . VAL A 1 335 ? 121.785 125.535 100.301 1.00 66.27  ? 335 VAL A CA  1 
ATOM 1588 C C   . VAL A 1 335 ? 121.780 124.219 101.067 1.00 74.84  ? 335 VAL A C   1 
ATOM 1589 O O   . VAL A 1 335 ? 120.717 123.672 101.382 1.00 73.77  ? 335 VAL A O   1 
ATOM 1590 C CB  . VAL A 1 335 ? 121.933 125.312 98.785  1.00 60.68  ? 335 VAL A CB  1 
ATOM 1591 C CG1 . VAL A 1 335 ? 120.808 124.434 98.262  1.00 65.98  ? 335 VAL A CG1 1 
ATOM 1592 C CG2 . VAL A 1 335 ? 121.958 126.643 98.054  1.00 71.11  ? 335 VAL A CG2 1 
ATOM 1593 N N   . PHE A 1 336 ? 122.965 123.694 101.386 1.00 80.50  ? 336 PHE A N   1 
ATOM 1594 C CA  . PHE A 1 336 ? 123.041 122.471 102.178 1.00 76.53  ? 336 PHE A CA  1 
ATOM 1595 C C   . PHE A 1 336 ? 122.453 122.677 103.569 1.00 69.37  ? 336 PHE A C   1 
ATOM 1596 O O   . PHE A 1 336 ? 121.712 121.825 104.072 1.00 75.15  ? 336 PHE A O   1 
ATOM 1597 C CB  . PHE A 1 336 ? 124.492 121.998 102.272 1.00 77.38  ? 336 PHE A CB  1 
ATOM 1598 C CG  . PHE A 1 336 ? 124.703 120.869 103.240 1.00 77.64  ? 336 PHE A CG  1 
ATOM 1599 C CD1 . PHE A 1 336 ? 124.288 119.584 102.931 1.00 79.12  ? 336 PHE A CD1 1 
ATOM 1600 C CD2 . PHE A 1 336 ? 125.321 121.093 104.460 1.00 77.21  ? 336 PHE A CD2 1 
ATOM 1601 C CE1 . PHE A 1 336 ? 124.483 118.546 103.821 1.00 79.84  ? 336 PHE A CE1 1 
ATOM 1602 C CE2 . PHE A 1 336 ? 125.517 120.058 105.353 1.00 79.84  ? 336 PHE A CE2 1 
ATOM 1603 C CZ  . PHE A 1 336 ? 125.099 118.783 105.033 1.00 79.78  ? 336 PHE A CZ  1 
ATOM 1604 N N   . ASP A 1 337 ? 122.777 123.804 104.209 1.00 63.92  ? 337 ASP A N   1 
ATOM 1605 C CA  . ASP A 1 337 ? 122.218 124.097 105.524 1.00 67.29  ? 337 ASP A CA  1 
ATOM 1606 C C   . ASP A 1 337 ? 120.712 124.328 105.455 1.00 69.52  ? 337 ASP A C   1 
ATOM 1607 O O   . ASP A 1 337 ? 119.962 123.816 106.295 1.00 79.35  ? 337 ASP A O   1 
ATOM 1608 C CB  . ASP A 1 337 ? 122.919 125.311 106.132 1.00 76.94  ? 337 ASP A CB  1 
ATOM 1609 C CG  . ASP A 1 337 ? 124.347 125.011 106.548 1.00 80.48  ? 337 ASP A CG  1 
ATOM 1610 O OD1 . ASP A 1 337 ? 124.704 123.817 106.633 1.00 80.93  ? 337 ASP A OD1 1 
ATOM 1611 O OD2 . ASP A 1 337 ? 125.113 125.968 106.791 1.00 77.86  ? 337 ASP A OD2 1 
ATOM 1612 N N   . ALA A 1 338 ? 120.254 125.102 104.468 1.00 52.79  ? 338 ALA A N   1 
ATOM 1613 C CA  . ALA A 1 338 ? 118.829 125.397 104.357 1.00 53.87  ? 338 ALA A CA  1 
ATOM 1614 C C   . ALA A 1 338 ? 118.019 124.143 104.049 1.00 67.42  ? 338 ALA A C   1 
ATOM 1615 O O   . ALA A 1 338 ? 116.917 123.964 104.581 1.00 69.53  ? 338 ALA A O   1 
ATOM 1616 C CB  . ALA A 1 338 ? 118.595 126.462 103.287 1.00 63.75  ? 338 ALA A CB  1 
ATOM 1617 N N   . VAL A 1 339 ? 118.548 123.262 103.198 1.00 64.48  ? 339 VAL A N   1 
ATOM 1618 C CA  . VAL A 1 339 ? 117.852 122.015 102.892 1.00 58.45  ? 339 VAL A CA  1 
ATOM 1619 C C   . VAL A 1 339 ? 117.825 121.105 104.112 1.00 57.67  ? 339 VAL A C   1 
ATOM 1620 O O   . VAL A 1 339 ? 116.829 120.417 104.369 1.00 47.53  ? 339 VAL A O   1 
ATOM 1621 C CB  . VAL A 1 339 ? 118.502 121.327 101.676 1.00 56.19  ? 339 VAL A CB  1 
ATOM 1622 C CG1 . VAL A 1 339 ? 118.067 119.876 101.585 1.00 65.60  ? 339 VAL A CG1 1 
ATOM 1623 C CG2 . VAL A 1 339 ? 118.134 122.061 100.397 1.00 58.10  ? 339 VAL A CG2 1 
ATOM 1624 N N   . THR A 1 340 ? 118.907 121.100 104.895 1.00 66.73  ? 340 THR A N   1 
ATOM 1625 C CA  . THR A 1 340 ? 118.936 120.295 106.112 1.00 54.15  ? 340 THR A CA  1 
ATOM 1626 C C   . THR A 1 340 ? 117.829 120.707 107.075 1.00 56.62  ? 340 THR A C   1 
ATOM 1627 O O   . THR A 1 340 ? 117.163 119.851 107.668 1.00 68.61  ? 340 THR A O   1 
ATOM 1628 C CB  . THR A 1 340 ? 120.305 120.409 106.786 1.00 55.12  ? 340 THR A CB  1 
ATOM 1629 O OG1 . THR A 1 340 ? 121.321 119.941 105.891 1.00 64.77  ? 340 THR A OG1 1 
ATOM 1630 C CG2 . THR A 1 340 ? 120.346 119.579 108.059 1.00 51.45  ? 340 THR A CG2 1 
ATOM 1631 N N   . ASP A 1 341 ? 117.610 122.015 107.237 1.00 58.07  ? 341 ASP A N   1 
ATOM 1632 C CA  . ASP A 1 341 ? 116.516 122.473 108.087 1.00 65.17  ? 341 ASP A CA  1 
ATOM 1633 C C   . ASP A 1 341 ? 115.153 122.108 107.511 1.00 66.03  ? 341 ASP A C   1 
ATOM 1634 O O   . ASP A 1 341 ? 114.204 121.880 108.271 1.00 69.73  ? 341 ASP A O   1 
ATOM 1635 C CB  . ASP A 1 341 ? 116.614 123.982 108.304 1.00 66.86  ? 341 ASP A CB  1 
ATOM 1636 C CG  . ASP A 1 341 ? 115.616 124.489 109.326 1.00 71.06  ? 341 ASP A CG  1 
ATOM 1637 O OD1 . ASP A 1 341 ? 115.855 124.302 110.538 1.00 72.03  ? 341 ASP A OD1 1 
ATOM 1638 O OD2 . ASP A 1 341 ? 114.591 125.074 108.917 1.00 72.28  ? 341 ASP A OD2 1 
ATOM 1639 N N   . VAL A 1 342 ? 115.029 122.048 106.183 1.00 60.36  ? 342 VAL A N   1 
ATOM 1640 C CA  . VAL A 1 342 ? 113.781 121.588 105.580 1.00 62.84  ? 342 VAL A CA  1 
ATOM 1641 C C   . VAL A 1 342 ? 113.582 120.100 105.840 1.00 65.47  ? 342 VAL A C   1 
ATOM 1642 O O   . VAL A 1 342 ? 112.460 119.645 106.093 1.00 71.95  ? 342 VAL A O   1 
ATOM 1643 C CB  . VAL A 1 342 ? 113.755 121.910 104.076 1.00 62.61  ? 342 VAL A CB  1 
ATOM 1644 C CG1 . VAL A 1 342 ? 112.499 121.336 103.435 1.00 56.85  ? 342 VAL A CG1 1 
ATOM 1645 C CG2 . VAL A 1 342 ? 113.835 123.406 103.853 1.00 67.99  ? 342 VAL A CG2 1 
ATOM 1646 N N   . ILE A 1 343 ? 114.664 119.320 105.783 1.00 59.00  ? 343 ILE A N   1 
ATOM 1647 C CA  . ILE A 1 343 ? 114.559 117.884 106.030 1.00 57.81  ? 343 ILE A CA  1 
ATOM 1648 C C   . ILE A 1 343 ? 114.108 117.626 107.461 1.00 59.17  ? 343 ILE A C   1 
ATOM 1649 O O   . ILE A 1 343 ? 113.254 116.766 107.712 1.00 60.74  ? 343 ILE A O   1 
ATOM 1650 C CB  . ILE A 1 343 ? 115.897 117.185 105.721 1.00 56.28  ? 343 ILE A CB  1 
ATOM 1651 C CG1 . ILE A 1 343 ? 116.198 117.254 104.223 1.00 52.35  ? 343 ILE A CG1 1 
ATOM 1652 C CG2 . ILE A 1 343 ? 115.865 115.740 106.186 1.00 55.78  ? 343 ILE A CG2 1 
ATOM 1653 C CD1 . ILE A 1 343 ? 117.485 116.566 103.826 1.00 54.51  ? 343 ILE A CD1 1 
ATOM 1654 N N   . ILE A 1 344 ? 114.676 118.361 108.420 1.00 49.11  ? 344 ILE A N   1 
ATOM 1655 C CA  . ILE A 1 344 ? 114.257 118.223 109.812 1.00 45.27  ? 344 ILE A CA  1 
ATOM 1656 C C   . ILE A 1 344 ? 112.775 118.540 109.950 1.00 46.75  ? 344 ILE A C   1 
ATOM 1657 O O   . ILE A 1 344 ? 112.032 117.826 110.636 1.00 68.10  ? 344 ILE A O   1 
ATOM 1658 C CB  . ILE A 1 344 ? 115.111 119.128 110.719 1.00 48.42  ? 344 ILE A CB  1 
ATOM 1659 C CG1 . ILE A 1 344 ? 116.587 118.738 110.631 1.00 49.28  ? 344 ILE A CG1 1 
ATOM 1660 C CG2 . ILE A 1 344 ? 114.622 119.058 112.153 1.00 56.41  ? 344 ILE A CG2 1 
ATOM 1661 C CD1 . ILE A 1 344 ? 117.503 119.611 111.461 1.00 54.16  ? 344 ILE A CD1 1 
ATOM 1662 N N   . LYS A 1 345 ? 112.322 119.615 109.300 1.00 42.08  ? 345 LYS A N   1 
ATOM 1663 C CA  . LYS A 1 345 ? 110.914 119.993 109.370 1.00 56.35  ? 345 LYS A CA  1 
ATOM 1664 C C   . LYS A 1 345 ? 110.017 118.909 108.787 1.00 57.63  ? 345 LYS A C   1 
ATOM 1665 O O   . LYS A 1 345 ? 108.945 118.620 109.332 1.00 68.35  ? 345 LYS A O   1 
ATOM 1666 C CB  . LYS A 1 345 ? 110.693 121.319 108.643 1.00 62.41  ? 345 LYS A CB  1 
ATOM 1667 C CG  . LYS A 1 345 ? 109.254 121.802 108.657 1.00 60.89  ? 345 LYS A CG  1 
ATOM 1668 C CD  . LYS A 1 345 ? 109.105 123.110 107.899 1.00 66.72  ? 345 LYS A CD  1 
ATOM 1669 C CE  . LYS A 1 345 ? 107.664 123.592 107.910 1.00 61.51  ? 345 LYS A CE  1 
ATOM 1670 N NZ  . LYS A 1 345 ? 107.504 124.870 107.165 1.00 62.47  ? 345 LYS A NZ  1 
ATOM 1671 N N   . ASN A 1 346 ? 110.436 118.298 107.676 1.00 50.82  ? 346 ASN A N   1 
ATOM 1672 C CA  . ASN A 1 346 ? 109.637 117.235 107.074 1.00 51.59  ? 346 ASN A CA  1 
ATOM 1673 C C   . ASN A 1 346 ? 109.616 115.992 107.955 1.00 59.98  ? 346 ASN A C   1 
ATOM 1674 O O   . ASN A 1 346 ? 108.601 115.290 108.024 1.00 66.37  ? 346 ASN A O   1 
ATOM 1675 C CB  . ASN A 1 346 ? 110.175 116.895 105.684 1.00 58.05  ? 346 ASN A CB  1 
ATOM 1676 C CG  . ASN A 1 346 ? 110.058 118.052 104.713 1.00 69.87  ? 346 ASN A CG  1 
ATOM 1677 O OD1 . ASN A 1 346 ? 109.112 118.837 104.775 1.00 78.93  ? 346 ASN A OD1 1 
ATOM 1678 N ND2 . ASN A 1 346 ? 111.019 118.159 103.803 1.00 64.93  ? 346 ASN A ND2 1 
ATOM 1679 N N   . ASN A 1 347 ? 110.731 115.702 108.629 1.00 61.65  ? 347 ASN A N   1 
ATOM 1680 C CA  . ASN A 1 347 ? 110.774 114.556 109.532 1.00 55.46  ? 347 ASN A CA  1 
ATOM 1681 C C   . ASN A 1 347 ? 109.839 114.743 110.720 1.00 58.92  ? 347 ASN A C   1 
ATOM 1682 O O   . ASN A 1 347 ? 109.197 113.785 111.167 1.00 66.22  ? 347 ASN A O   1 
ATOM 1683 C CB  . ASN A 1 347 ? 112.206 114.318 110.010 1.00 53.72  ? 347 ASN A CB  1 
ATOM 1684 C CG  . ASN A 1 347 ? 113.106 113.783 108.915 1.00 57.97  ? 347 ASN A CG  1 
ATOM 1685 O OD1 . ASN A 1 347 ? 112.636 113.193 107.941 1.00 63.62  ? 347 ASN A OD1 1 
ATOM 1686 N ND2 . ASN A 1 347 ? 114.410 113.979 109.072 1.00 62.07  ? 347 ASN A ND2 1 
ATOM 1687 N N   . LEU A 1 348 ? 109.755 115.966 111.251 1.00 51.74  ? 348 LEU A N   1 
ATOM 1688 C CA  . LEU A 1 348 ? 108.855 116.229 112.370 1.00 51.86  ? 348 LEU A CA  1 
ATOM 1689 C C   . LEU A 1 348 ? 107.399 115.995 111.985 1.00 59.65  ? 348 LEU A C   1 
ATOM 1690 O O   . LEU A 1 348 ? 106.621 115.452 112.779 1.00 65.43  ? 348 LEU A O   1 
ATOM 1691 C CB  . LEU A 1 348 ? 109.050 117.657 112.880 1.00 48.81  ? 348 LEU A CB  1 
ATOM 1692 C CG  . LEU A 1 348 ? 110.432 118.012 113.433 1.00 46.54  ? 348 LEU A CG  1 
ATOM 1693 C CD1 . LEU A 1 348 ? 110.432 119.421 114.005 1.00 52.33  ? 348 LEU A CD1 1 
ATOM 1694 C CD2 . LEU A 1 348 ? 110.872 117.005 114.482 1.00 49.79  ? 348 LEU A CD2 1 
ATOM 1695 N N   . LYS A 1 349 ? 107.008 116.404 110.775 1.00 55.29  ? 349 LYS A N   1 
ATOM 1696 C CA  . LYS A 1 349 ? 105.637 116.170 110.331 1.00 55.42  ? 349 LYS A CA  1 
ATOM 1697 C C   . LYS A 1 349 ? 105.347 114.681 110.192 1.00 61.96  ? 349 LYS A C   1 
ATOM 1698 O O   . LYS A 1 349 ? 104.282 114.207 110.605 1.00 69.51  ? 349 LYS A O   1 
ATOM 1699 C CB  . LYS A 1 349 ? 105.382 116.890 109.008 1.00 59.25  ? 349 LYS A CB  1 
ATOM 1700 C CG  . LYS A 1 349 ? 105.418 118.406 109.106 1.00 65.67  ? 349 LYS A CG  1 
ATOM 1701 C CD  . LYS A 1 349 ? 105.089 119.053 107.770 1.00 65.37  ? 349 LYS A CD  1 
ATOM 1702 C CE  . LYS A 1 349 ? 105.088 120.570 107.875 1.00 65.73  ? 349 LYS A CE  1 
ATOM 1703 N NZ  . LYS A 1 349 ? 104.736 121.216 106.581 1.00 65.97  ? 349 LYS A NZ  1 
ATOM 1704 N N   . ASP A 1 350 ? 106.280 113.927 109.606 1.00 62.36  ? 350 ASP A N   1 
ATOM 1705 C CA  . ASP A 1 350 ? 106.068 112.493 109.436 1.00 62.36  ? 350 ASP A CA  1 
ATOM 1706 C C   . ASP A 1 350 ? 106.061 111.774 110.780 1.00 61.84  ? 350 ASP A C   1 
ATOM 1707 O O   . ASP A 1 350 ? 105.234 110.885 111.011 1.00 63.35  ? 350 ASP A O   1 
ATOM 1708 C CB  . ASP A 1 350 ? 107.139 111.909 108.515 1.00 66.34  ? 350 ASP A CB  1 
ATOM 1709 C CG  . ASP A 1 350 ? 107.023 112.419 107.090 1.00 69.93  ? 350 ASP A CG  1 
ATOM 1710 O OD1 . ASP A 1 350 ? 105.898 112.760 106.669 1.00 70.56  ? 350 ASP A OD1 1 
ATOM 1711 O OD2 . ASP A 1 350 ? 108.056 112.477 106.390 1.00 67.81  ? 350 ASP A OD2 1 
ATOM 1712 N N   . CYS A 1 351 ? 106.980 112.141 111.676 1.00 58.75  ? 351 CYS A N   1 
ATOM 1713 C CA  . CYS A 1 351 ? 107.052 111.507 112.987 1.00 57.37  ? 351 CYS A CA  1 
ATOM 1714 C C   . CYS A 1 351 ? 105.912 111.920 113.910 1.00 58.93  ? 351 CYS A C   1 
ATOM 1715 O O   . CYS A 1 351 ? 105.754 111.318 114.976 1.00 65.42  ? 351 CYS A O   1 
ATOM 1716 C CB  . CYS A 1 351 ? 108.395 111.826 113.646 1.00 59.39  ? 351 CYS A CB  1 
ATOM 1717 S SG  . CYS A 1 351 ? 109.828 111.103 112.812 1.00 83.35  ? 351 CYS A SG  1 
ATOM 1718 N N   . GLY A 1 352 ? 105.119 112.920 113.530 1.00 53.39  ? 352 GLY A N   1 
ATOM 1719 C CA  . GLY A 1 352 ? 104.006 113.371 114.338 1.00 53.73  ? 352 GLY A CA  1 
ATOM 1720 C C   . GLY A 1 352 ? 104.338 114.391 115.405 1.00 48.38  ? 352 GLY A C   1 
ATOM 1721 O O   . GLY A 1 352 ? 103.433 114.803 116.143 1.00 47.98  ? 352 GLY A O   1 
ATOM 1722 N N   . LEU A 1 353 ? 105.600 114.812 115.518 1.00 43.71  ? 353 LEU A N   1 
ATOM 1723 C CA  . LEU A 1 353 ? 105.950 115.819 116.515 1.00 39.56  ? 353 LEU A CA  1 
ATOM 1724 C C   . LEU A 1 353 ? 105.362 117.184 116.180 1.00 54.17  ? 353 LEU A C   1 
ATOM 1725 O O   . LEU A 1 353 ? 104.993 117.935 117.090 1.00 63.81  ? 353 LEU A O   1 
ATOM 1726 C CB  . LEU A 1 353 ? 107.468 115.911 116.652 1.00 40.05  ? 353 LEU A CB  1 
ATOM 1727 C CG  . LEU A 1 353 ? 108.123 114.682 117.282 1.00 47.90  ? 353 LEU A CG  1 
ATOM 1728 C CD1 . LEU A 1 353 ? 109.627 114.863 117.396 1.00 43.20  ? 353 LEU A CD1 1 
ATOM 1729 C CD2 . LEU A 1 353 ? 107.507 114.411 118.642 1.00 55.88  ? 353 LEU A CD2 1 
ATOM 1730 N N   . PHE A 1 354 ? 105.264 117.523 114.899 1.00 65.93  ? 354 PHE A N   1 
ATOM 1731 C CA  . PHE A 1 354 ? 104.712 118.810 114.492 1.00 63.60  ? 354 PHE A CA  1 
ATOM 1732 C C   . PHE A 1 354 ? 103.196 118.823 114.654 1.00 64.62  ? 354 PHE A C   1 
ATOM 1733 O O   . PHE A 1 354 ? 102.511 117.894 114.230 1.00 60.41  ? 354 PHE A O   1 
ATOM 1734 C CB  . PHE A 1 354 ? 105.095 119.131 113.046 1.00 57.71  ? 354 PHE A CB  1 
ATOM 1735 C CG  . PHE A 1 354 ? 105.355 120.592 112.796 1.00 59.03  ? 354 PHE A CG  1 
ATOM 1736 C CD1 . PHE A 1 354 ? 104.555 121.563 113.375 1.00 60.94  ? 354 PHE A CD1 1 
ATOM 1737 C CD2 . PHE A 1 354 ? 106.404 120.993 111.985 1.00 66.88  ? 354 PHE A CD2 1 
ATOM 1738 C CE1 . PHE A 1 354 ? 104.793 122.906 113.149 1.00 60.25  ? 354 PHE A CE1 1 
ATOM 1739 C CE2 . PHE A 1 354 ? 106.648 122.335 111.755 1.00 68.64  ? 354 PHE A CE2 1 
ATOM 1740 C CZ  . PHE A 1 354 ? 105.841 123.292 112.338 1.00 66.31  ? 354 PHE A CZ  1 
ATOM 1741 O OXT . PHE A 1 354 ? 102.620 119.761 115.204 1.00 68.74  ? 354 PHE A OXT 1 
ATOM 1742 N N   . SER B 2 12  ? 99.097  151.449 57.677  1.00 205.36 ? 2   SER B N   1 
ATOM 1743 C CA  . SER B 2 12  ? 98.105  151.547 56.612  1.00 205.59 ? 2   SER B CA  1 
ATOM 1744 C C   . SER B 2 12  ? 97.643  150.165 56.164  1.00 205.73 ? 2   SER B C   1 
ATOM 1745 O O   . SER B 2 12  ? 96.493  149.784 56.382  1.00 205.55 ? 2   SER B O   1 
ATOM 1746 C CB  . SER B 2 12  ? 98.672  152.325 55.422  1.00 205.00 ? 2   SER B CB  1 
ATOM 1747 O OG  . SER B 2 12  ? 99.821  151.685 54.895  1.00 204.17 ? 2   SER B OG  1 
ATOM 1748 N N   . GLU B 2 13  ? 98.551  149.419 55.529  1.00 212.64 ? 3   GLU B N   1 
ATOM 1749 C CA  . GLU B 2 13  ? 98.215  148.073 55.075  1.00 213.08 ? 3   GLU B CA  1 
ATOM 1750 C C   . GLU B 2 13  ? 97.928  147.147 56.250  1.00 213.47 ? 3   GLU B C   1 
ATOM 1751 O O   . GLU B 2 13  ? 96.995  146.338 56.199  1.00 213.35 ? 3   GLU B O   1 
ATOM 1752 C CB  . GLU B 2 13  ? 99.348  147.513 54.214  1.00 212.57 ? 3   GLU B CB  1 
ATOM 1753 C CG  . GLU B 2 13  ? 99.071  146.134 53.635  1.00 212.37 ? 3   GLU B CG  1 
ATOM 1754 C CD  . GLU B 2 13  ? 97.983  146.147 52.577  1.00 212.28 ? 3   GLU B CD  1 
ATOM 1755 O OE1 . GLU B 2 13  ? 97.733  147.221 51.989  1.00 212.59 ? 3   GLU B OE1 1 
ATOM 1756 O OE2 . GLU B 2 13  ? 97.377  145.083 52.334  1.00 211.51 ? 3   GLU B OE2 1 
ATOM 1757 N N   . LEU B 2 14  ? 98.723  147.250 57.318  1.00 214.09 ? 4   LEU B N   1 
ATOM 1758 C CA  . LEU B 2 14  ? 98.500  146.412 58.493  1.00 213.59 ? 4   LEU B CA  1 
ATOM 1759 C C   . LEU B 2 14  ? 97.165  146.731 59.154  1.00 213.60 ? 4   LEU B C   1 
ATOM 1760 O O   . LEU B 2 14  ? 96.434  145.822 59.565  1.00 213.41 ? 4   LEU B O   1 
ATOM 1761 C CB  . LEU B 2 14  ? 99.648  146.587 59.487  1.00 212.56 ? 4   LEU B CB  1 
ATOM 1762 C CG  . LEU B 2 14  ? 99.560  145.772 60.779  1.00 211.58 ? 4   LEU B CG  1 
ATOM 1763 C CD1 . LEU B 2 14  ? 99.531  144.283 60.474  1.00 211.77 ? 4   LEU B CD1 1 
ATOM 1764 C CD2 . LEU B 2 14  ? 100.716 146.112 61.708  1.00 211.95 ? 4   LEU B CD2 1 
ATOM 1765 N N   . ASP B 2 15  ? 96.834  148.019 59.275  1.00 215.58 ? 5   ASP B N   1 
ATOM 1766 C CA  . ASP B 2 15  ? 95.561  148.406 59.877  1.00 215.32 ? 5   ASP B CA  1 
ATOM 1767 C C   . ASP B 2 15  ? 94.381  147.902 59.055  1.00 215.12 ? 5   ASP B C   1 
ATOM 1768 O O   . ASP B 2 15  ? 93.379  147.441 59.612  1.00 214.40 ? 5   ASP B O   1 
ATOM 1769 C CB  . ASP B 2 15  ? 95.496  149.926 60.032  1.00 214.83 ? 5   ASP B CB  1 
ATOM 1770 C CG  . ASP B 2 15  ? 96.614  150.472 60.898  1.00 214.76 ? 5   ASP B CG  1 
ATOM 1771 O OD1 . ASP B 2 15  ? 97.442  149.669 61.378  1.00 215.92 ? 5   ASP B OD1 1 
ATOM 1772 O OD2 . ASP B 2 15  ? 96.665  151.703 61.099  1.00 213.84 ? 5   ASP B OD2 1 
ATOM 1773 N N   . GLN B 2 16  ? 94.477  147.992 57.726  1.00 217.22 ? 6   GLN B N   1 
ATOM 1774 C CA  . GLN B 2 16  ? 93.394  147.515 56.872  1.00 217.18 ? 6   GLN B CA  1 
ATOM 1775 C C   . GLN B 2 16  ? 93.209  146.007 56.997  1.00 217.41 ? 6   GLN B C   1 
ATOM 1776 O O   . GLN B 2 16  ? 92.076  145.514 57.033  1.00 217.61 ? 6   GLN B O   1 
ATOM 1777 C CB  . GLN B 2 16  ? 93.663  147.911 55.419  1.00 216.87 ? 6   GLN B CB  1 
ATOM 1778 C CG  . GLN B 2 16  ? 92.519  147.614 54.457  1.00 216.71 ? 6   GLN B CG  1 
ATOM 1779 C CD  . GLN B 2 16  ? 92.605  146.229 53.846  1.00 216.08 ? 6   GLN B CD  1 
ATOM 1780 O OE1 . GLN B 2 16  ? 93.625  145.549 53.960  1.00 215.65 ? 6   GLN B OE1 1 
ATOM 1781 N NE2 . GLN B 2 16  ? 91.531  145.803 53.191  1.00 215.54 ? 6   GLN B NE2 1 
ATOM 1782 N N   . LEU B 2 17  ? 94.313  145.257 57.057  1.00 213.95 ? 7   LEU B N   1 
ATOM 1783 C CA  . LEU B 2 17  ? 94.218  143.801 57.124  1.00 213.31 ? 7   LEU B CA  1 
ATOM 1784 C C   . LEU B 2 17  ? 93.581  143.336 58.429  1.00 213.53 ? 7   LEU B C   1 
ATOM 1785 O O   . LEU B 2 17  ? 92.738  142.431 58.422  1.00 212.80 ? 7   LEU B O   1 
ATOM 1786 C CB  . LEU B 2 17  ? 95.601  143.175 56.949  1.00 212.55 ? 7   LEU B CB  1 
ATOM 1787 C CG  . LEU B 2 17  ? 96.181  143.219 55.534  1.00 212.32 ? 7   LEU B CG  1 
ATOM 1788 C CD1 . LEU B 2 17  ? 97.500  142.466 55.471  1.00 211.93 ? 7   LEU B CD1 1 
ATOM 1789 C CD2 . LEU B 2 17  ? 95.190  142.653 54.529  1.00 212.53 ? 7   LEU B CD2 1 
ATOM 1790 N N   . ARG B 2 18  ? 93.970  143.934 59.558  1.00 212.76 ? 8   ARG B N   1 
ATOM 1791 C CA  . ARG B 2 18  ? 93.403  143.519 60.837  1.00 212.16 ? 8   ARG B CA  1 
ATOM 1792 C C   . ARG B 2 18  ? 91.928  143.878 60.965  1.00 211.87 ? 8   ARG B C   1 
ATOM 1793 O O   . ARG B 2 18  ? 91.225  143.267 61.776  1.00 211.45 ? 8   ARG B O   1 
ATOM 1794 C CB  . ARG B 2 18  ? 94.194  144.131 61.997  1.00 211.83 ? 8   ARG B CB  1 
ATOM 1795 C CG  . ARG B 2 18  ? 94.006  145.628 62.177  1.00 211.01 ? 8   ARG B CG  1 
ATOM 1796 C CD  . ARG B 2 18  ? 94.559  146.088 63.517  1.00 210.76 ? 8   ARG B CD  1 
ATOM 1797 N NE  . ARG B 2 18  ? 94.361  147.516 63.733  1.00 210.39 ? 8   ARG B NE  1 
ATOM 1798 C CZ  . ARG B 2 18  ? 95.288  148.441 63.525  1.00 210.94 ? 8   ARG B CZ  1 
ATOM 1799 N NH1 . ARG B 2 18  ? 96.500  148.121 63.102  1.00 211.23 ? 8   ARG B NH1 1 
ATOM 1800 N NH2 . ARG B 2 18  ? 94.993  149.718 63.750  1.00 211.15 ? 8   ARG B NH2 1 
ATOM 1801 N N   . GLN B 2 19  ? 91.444  144.850 60.188  1.00 208.13 ? 9   GLN B N   1 
ATOM 1802 C CA  . GLN B 2 19  ? 90.009  145.109 60.149  1.00 207.72 ? 9   GLN B CA  1 
ATOM 1803 C C   . GLN B 2 19  ? 89.276  144.016 59.383  1.00 207.02 ? 9   GLN B C   1 
ATOM 1804 O O   . GLN B 2 19  ? 88.146  143.654 59.734  1.00 206.75 ? 9   GLN B O   1 
ATOM 1805 C CB  . GLN B 2 19  ? 89.736  146.479 59.529  1.00 207.45 ? 9   GLN B CB  1 
ATOM 1806 C CG  . GLN B 2 19  ? 90.226  147.649 60.367  1.00 207.06 ? 9   GLN B CG  1 
ATOM 1807 C CD  . GLN B 2 19  ? 89.945  148.990 59.717  1.00 206.79 ? 9   GLN B CD  1 
ATOM 1808 O OE1 . GLN B 2 19  ? 89.383  149.057 58.624  1.00 206.82 ? 9   GLN B OE1 1 
ATOM 1809 N NE2 . GLN B 2 19  ? 90.337  150.066 60.388  1.00 206.45 ? 9   GLN B NE2 1 
ATOM 1810 N N   . GLU B 2 20  ? 89.901  143.482 58.331  1.00 204.20 ? 10  GLU B N   1 
ATOM 1811 C CA  . GLU B 2 20  ? 89.290  142.393 57.576  1.00 203.79 ? 10  GLU B CA  1 
ATOM 1812 C C   . GLU B 2 20  ? 89.189  141.121 58.408  1.00 204.07 ? 10  GLU B C   1 
ATOM 1813 O O   . GLU B 2 20  ? 88.234  140.352 58.248  1.00 204.09 ? 10  GLU B O   1 
ATOM 1814 C CB  . GLU B 2 20  ? 90.085  142.133 56.296  1.00 203.73 ? 10  GLU B CB  1 
ATOM 1815 C CG  . GLU B 2 20  ? 89.480  141.076 55.385  1.00 203.42 ? 10  GLU B CG  1 
ATOM 1816 C CD  . GLU B 2 20  ? 90.308  140.839 54.138  1.00 203.94 ? 10  GLU B CD  1 
ATOM 1817 O OE1 . GLU B 2 20  ? 91.360  141.494 53.988  1.00 203.70 ? 10  GLU B OE1 1 
ATOM 1818 O OE2 . GLU B 2 20  ? 89.906  139.997 53.307  1.00 204.27 ? 10  GLU B OE2 1 
ATOM 1819 N N   . ALA B 2 21  ? 90.157  140.886 59.298  1.00 203.45 ? 11  ALA B N   1 
ATOM 1820 C CA  . ALA B 2 21  ? 90.089  139.725 60.180  1.00 203.24 ? 11  ALA B CA  1 
ATOM 1821 C C   . ALA B 2 21  ? 88.879  139.803 61.102  1.00 203.49 ? 11  ALA B C   1 
ATOM 1822 O O   . ALA B 2 21  ? 88.206  138.793 61.341  1.00 203.40 ? 11  ALA B O   1 
ATOM 1823 C CB  . ALA B 2 21  ? 91.378  139.606 60.992  1.00 202.45 ? 11  ALA B CB  1 
ATOM 1824 N N   . GLU B 2 22  ? 88.591  140.993 61.634  1.00 200.32 ? 12  GLU B N   1 
ATOM 1825 C CA  . GLU B 2 22  ? 87.413  141.163 62.479  1.00 199.78 ? 12  GLU B CA  1 
ATOM 1826 C C   . GLU B 2 22  ? 86.133  140.895 61.699  1.00 199.90 ? 12  GLU B C   1 
ATOM 1827 O O   . GLU B 2 22  ? 85.189  140.295 62.227  1.00 199.54 ? 12  GLU B O   1 
ATOM 1828 C CB  . GLU B 2 22  ? 87.395  142.570 63.078  1.00 198.76 ? 12  GLU B CB  1 
ATOM 1829 C CG  . GLU B 2 22  ? 88.574  142.874 63.990  1.00 198.45 ? 12  GLU B CG  1 
ATOM 1830 C CD  . GLU B 2 22  ? 88.534  142.086 65.285  1.00 199.26 ? 12  GLU B CD  1 
ATOM 1831 O OE1 . GLU B 2 22  ? 87.437  141.635 65.678  1.00 200.17 ? 12  GLU B OE1 1 
ATOM 1832 O OE2 . GLU B 2 22  ? 89.601  141.916 65.912  1.00 199.04 ? 12  GLU B OE2 1 
ATOM 1833 N N   . GLN B 2 23  ? 86.078  141.340 60.440  1.00 195.96 ? 13  GLN B N   1 
ATOM 1834 C CA  . GLN B 2 23  ? 84.916  141.056 59.605  1.00 194.97 ? 13  GLN B CA  1 
ATOM 1835 C C   . GLN B 2 23  ? 84.758  139.559 59.370  1.00 194.24 ? 13  GLN B C   1 
ATOM 1836 O O   . GLN B 2 23  ? 83.637  139.036 59.379  1.00 193.78 ? 13  GLN B O   1 
ATOM 1837 C CB  . GLN B 2 23  ? 85.030  141.800 58.275  1.00 194.87 ? 13  GLN B CB  1 
ATOM 1838 C CG  . GLN B 2 23  ? 85.075  143.313 58.411  1.00 194.29 ? 13  GLN B CG  1 
ATOM 1839 C CD  . GLN B 2 23  ? 85.172  144.016 57.071  1.00 193.52 ? 13  GLN B CD  1 
ATOM 1840 O OE1 . GLN B 2 23  ? 85.213  143.373 56.022  1.00 193.32 ? 13  GLN B OE1 1 
ATOM 1841 N NE2 . GLN B 2 23  ? 85.208  145.343 57.100  1.00 193.56 ? 13  GLN B NE2 1 
ATOM 1842 N N   . LEU B 2 24  ? 85.870  138.852 59.152  1.00 186.59 ? 14  LEU B N   1 
ATOM 1843 C CA  . LEU B 2 24  ? 85.800  137.406 58.966  1.00 185.53 ? 14  LEU B CA  1 
ATOM 1844 C C   . LEU B 2 24  ? 85.351  136.707 60.244  1.00 185.20 ? 14  LEU B C   1 
ATOM 1845 O O   . LEU B 2 24  ? 84.583  135.739 60.191  1.00 185.40 ? 14  LEU B O   1 
ATOM 1846 C CB  . LEU B 2 24  ? 87.153  136.869 58.503  1.00 185.59 ? 14  LEU B CB  1 
ATOM 1847 C CG  . LEU B 2 24  ? 87.619  137.322 57.117  1.00 184.98 ? 14  LEU B CG  1 
ATOM 1848 C CD1 . LEU B 2 24  ? 88.973  136.717 56.778  1.00 184.95 ? 14  LEU B CD1 1 
ATOM 1849 C CD2 . LEU B 2 24  ? 86.587  136.962 56.060  1.00 185.18 ? 14  LEU B CD2 1 
ATOM 1850 N N   . LYS B 2 25  ? 85.827  137.177 61.400  1.00 183.93 ? 15  LYS B N   1 
ATOM 1851 C CA  . LYS B 2 25  ? 85.386  136.603 62.668  1.00 183.84 ? 15  LYS B CA  1 
ATOM 1852 C C   . LYS B 2 25  ? 83.894  136.825 62.880  1.00 184.40 ? 15  LYS B C   1 
ATOM 1853 O O   . LYS B 2 25  ? 83.188  135.932 63.364  1.00 183.66 ? 15  LYS B O   1 
ATOM 1854 C CB  . LYS B 2 25  ? 86.191  137.198 63.824  1.00 184.07 ? 15  LYS B CB  1 
ATOM 1855 C CG  . LYS B 2 25  ? 87.654  136.787 63.837  1.00 183.74 ? 15  LYS B CG  1 
ATOM 1856 C CD  . LYS B 2 25  ? 88.388  137.392 65.022  1.00 183.66 ? 15  LYS B CD  1 
ATOM 1857 C CE  . LYS B 2 25  ? 89.848  136.967 65.041  1.00 184.04 ? 15  LYS B CE  1 
ATOM 1858 N NZ  . LYS B 2 25  ? 90.580  137.547 66.200  1.00 184.05 ? 15  LYS B NZ  1 
ATOM 1859 N N   . ASN B 2 26  ? 83.398  138.014 62.529  1.00 185.22 ? 16  ASN B N   1 
ATOM 1860 C CA  . ASN B 2 26  ? 81.964  138.272 62.619  1.00 184.34 ? 16  ASN B CA  1 
ATOM 1861 C C   . ASN B 2 26  ? 81.188  137.401 61.640  1.00 184.25 ? 16  ASN B C   1 
ATOM 1862 O O   . ASN B 2 26  ? 80.070  136.967 61.939  1.00 183.72 ? 16  ASN B O   1 
ATOM 1863 C CB  . ASN B 2 26  ? 81.678  139.752 62.366  1.00 184.45 ? 16  ASN B CB  1 
ATOM 1864 C CG  . ASN B 2 26  ? 82.318  140.655 63.402  1.00 184.18 ? 16  ASN B CG  1 
ATOM 1865 O OD1 . ASN B 2 26  ? 82.499  140.266 64.555  1.00 183.43 ? 16  ASN B OD1 1 
ATOM 1866 N ND2 . ASN B 2 26  ? 82.664  141.871 62.994  1.00 184.69 ? 16  ASN B ND2 1 
ATOM 1867 N N   . GLN B 2 27  ? 81.764  137.142 60.463  1.00 181.22 ? 17  GLN B N   1 
ATOM 1868 C CA  . GLN B 2 27  ? 81.104  136.277 59.489  1.00 181.09 ? 17  GLN B CA  1 
ATOM 1869 C C   . GLN B 2 27  ? 80.945  134.863 60.033  1.00 180.89 ? 17  GLN B C   1 
ATOM 1870 O O   . GLN B 2 27  ? 79.896  134.234 59.852  1.00 179.59 ? 17  GLN B O   1 
ATOM 1871 C CB  . GLN B 2 27  ? 81.893  136.266 58.180  1.00 180.40 ? 17  GLN B CB  1 
ATOM 1872 C CG  . GLN B 2 27  ? 81.314  135.352 57.112  1.00 179.65 ? 17  GLN B CG  1 
ATOM 1873 C CD  . GLN B 2 27  ? 82.172  135.299 55.863  1.00 179.30 ? 17  GLN B CD  1 
ATOM 1874 O OE1 . GLN B 2 27  ? 83.215  135.948 55.785  1.00 179.44 ? 17  GLN B OE1 1 
ATOM 1875 N NE2 . GLN B 2 27  ? 81.737  134.523 54.878  1.00 179.57 ? 17  GLN B NE2 1 
ATOM 1876 N N   . ILE B 2 28  ? 81.979  134.345 60.699  1.00 183.37 ? 18  ILE B N   1 
ATOM 1877 C CA  . ILE B 2 28  ? 81.890  133.012 61.288  1.00 182.71 ? 18  ILE B CA  1 
ATOM 1878 C C   . ILE B 2 28  ? 80.868  132.999 62.417  1.00 182.19 ? 18  ILE B C   1 
ATOM 1879 O O   . ILE B 2 28  ? 80.065  132.066 62.536  1.00 182.26 ? 18  ILE B O   1 
ATOM 1880 C CB  . ILE B 2 28  ? 83.276  132.547 61.770  1.00 182.59 ? 18  ILE B CB  1 
ATOM 1881 C CG1 . ILE B 2 28  ? 84.257  132.490 60.597  1.00 182.13 ? 18  ILE B CG1 1 
ATOM 1882 C CG2 . ILE B 2 28  ? 83.178  131.190 62.452  1.00 181.17 ? 18  ILE B CG2 1 
ATOM 1883 C CD1 . ILE B 2 28  ? 85.652  132.050 60.989  1.00 180.91 ? 18  ILE B CD1 1 
ATOM 1884 N N   . ARG B 2 29  ? 80.882  134.032 63.265  1.00 182.10 ? 19  ARG B N   1 
ATOM 1885 C CA  . ARG B 2 29  ? 79.939  134.094 64.377  1.00 181.83 ? 19  ARG B CA  1 
ATOM 1886 C C   . ARG B 2 29  ? 78.501  134.172 63.878  1.00 181.80 ? 19  ARG B C   1 
ATOM 1887 O O   . ARG B 2 29  ? 77.604  133.535 64.442  1.00 182.06 ? 19  ARG B O   1 
ATOM 1888 C CB  . ARG B 2 29  ? 80.264  135.290 65.272  1.00 181.78 ? 19  ARG B CB  1 
ATOM 1889 C CG  . ARG B 2 29  ? 79.303  135.478 66.435  1.00 181.03 ? 19  ARG B CG  1 
ATOM 1890 C CD  . ARG B 2 29  ? 79.740  136.625 67.332  1.00 180.93 ? 19  ARG B CD  1 
ATOM 1891 N NE  . ARG B 2 29  ? 79.904  137.868 66.589  1.00 182.19 ? 19  ARG B NE  1 
ATOM 1892 C CZ  . ARG B 2 29  ? 78.941  138.759 66.398  1.00 182.42 ? 19  ARG B CZ  1 
ATOM 1893 N NH1 . ARG B 2 29  ? 77.724  138.576 66.884  1.00 182.44 ? 19  ARG B NH1 1 
ATOM 1894 N NH2 . ARG B 2 29  ? 79.205  139.861 65.701  1.00 182.20 ? 19  ARG B NH2 1 
ATOM 1895 N N   . ASP B 2 30  ? 78.263  134.953 62.821  1.00 181.08 ? 20  ASP B N   1 
ATOM 1896 C CA  . ASP B 2 30  ? 76.929  135.008 62.230  1.00 181.40 ? 20  ASP B CA  1 
ATOM 1897 C C   . ASP B 2 30  ? 76.543  133.667 61.618  1.00 181.16 ? 20  ASP B C   1 
ATOM 1898 O O   . ASP B 2 30  ? 75.379  133.256 61.696  1.00 181.20 ? 20  ASP B O   1 
ATOM 1899 C CB  . ASP B 2 30  ? 76.863  136.118 61.182  1.00 181.64 ? 20  ASP B CB  1 
ATOM 1900 C CG  . ASP B 2 30  ? 77.042  137.498 61.783  1.00 181.82 ? 20  ASP B CG  1 
ATOM 1901 O OD1 . ASP B 2 30  ? 76.680  137.686 62.963  1.00 182.04 ? 20  ASP B OD1 1 
ATOM 1902 O OD2 . ASP B 2 30  ? 77.544  138.396 61.074  1.00 181.12 ? 20  ASP B OD2 1 
ATOM 1903 N N   . ALA B 2 31  ? 77.503  132.978 60.996  1.00 173.70 ? 21  ALA B N   1 
ATOM 1904 C CA  . ALA B 2 31  ? 77.213  131.677 60.401  1.00 173.37 ? 21  ALA B CA  1 
ATOM 1905 C C   . ALA B 2 31  ? 76.826  130.659 61.466  1.00 172.34 ? 21  ALA B C   1 
ATOM 1906 O O   . ALA B 2 31  ? 75.903  129.860 61.265  1.00 171.52 ? 21  ALA B O   1 
ATOM 1907 C CB  . ALA B 2 31  ? 78.417  131.186 59.598  1.00 172.49 ? 21  ALA B CB  1 
ATOM 1908 N N   . ARG B 2 32  ? 77.526  130.666 62.603  1.00 162.38 ? 22  ARG B N   1 
ATOM 1909 C CA  . ARG B 2 32  ? 77.175  129.759 63.691  1.00 161.17 ? 22  ARG B CA  1 
ATOM 1910 C C   . ARG B 2 32  ? 75.810  130.101 64.275  1.00 162.22 ? 22  ARG B C   1 
ATOM 1911 O O   . ARG B 2 32  ? 75.028  129.203 64.608  1.00 162.58 ? 22  ARG B O   1 
ATOM 1912 C CB  . ARG B 2 32  ? 78.251  129.801 64.776  1.00 161.26 ? 22  ARG B CB  1 
ATOM 1913 C CG  . ARG B 2 32  ? 79.627  129.366 64.300  1.00 161.99 ? 22  ARG B CG  1 
ATOM 1914 C CD  . ARG B 2 32  ? 80.669  129.530 65.394  1.00 161.82 ? 22  ARG B CD  1 
ATOM 1915 N NE  . ARG B 2 32  ? 81.988  129.088 64.960  1.00 161.75 ? 22  ARG B NE  1 
ATOM 1916 C CZ  . ARG B 2 32  ? 83.075  129.112 65.720  1.00 161.61 ? 22  ARG B CZ  1 
ATOM 1917 N NH1 . ARG B 2 32  ? 83.036  129.554 66.966  1.00 160.41 ? 22  ARG B NH1 1 
ATOM 1918 N NH2 . ARG B 2 32  ? 84.229  128.684 65.216  1.00 160.60 ? 22  ARG B NH2 1 
ATOM 1919 N N   . LYS B 2 33  ? 75.510  131.395 64.416  1.00 172.07 ? 23  LYS B N   1 
ATOM 1920 C CA  . LYS B 2 33  ? 74.206  131.800 64.927  1.00 172.14 ? 23  LYS B CA  1 
ATOM 1921 C C   . LYS B 2 33  ? 73.086  131.431 63.962  1.00 173.20 ? 23  LYS B C   1 
ATOM 1922 O O   . LYS B 2 33  ? 71.963  131.148 64.396  1.00 172.41 ? 23  LYS B O   1 
ATOM 1923 C CB  . LYS B 2 33  ? 74.197  133.304 65.206  1.00 171.69 ? 23  LYS B CB  1 
ATOM 1924 C CG  . LYS B 2 33  ? 72.915  133.818 65.842  1.00 170.86 ? 23  LYS B CG  1 
ATOM 1925 C CD  . LYS B 2 33  ? 72.976  135.319 66.073  1.00 171.10 ? 23  LYS B CD  1 
ATOM 1926 C CE  . LYS B 2 33  ? 74.120  135.687 67.004  1.00 171.09 ? 23  LYS B CE  1 
ATOM 1927 N NZ  . LYS B 2 33  ? 73.979  135.042 68.338  1.00 171.73 ? 23  LYS B NZ  1 
ATOM 1928 N N   . ALA B 2 34  ? 73.371  131.428 62.657  1.00 178.65 ? 24  ALA B N   1 
ATOM 1929 C CA  . ALA B 2 34  ? 72.352  131.077 61.674  1.00 178.12 ? 24  ALA B CA  1 
ATOM 1930 C C   . ALA B 2 34  ? 71.904  129.630 61.830  1.00 177.57 ? 24  ALA B C   1 
ATOM 1931 O O   . ALA B 2 34  ? 70.710  129.325 61.716  1.00 176.96 ? 24  ALA B O   1 
ATOM 1932 C CB  . ALA B 2 34  ? 72.878  131.328 60.261  1.00 176.52 ? 24  ALA B CB  1 
ATOM 1933 N N   . CYS B 2 35  ? 72.843  128.724 62.090  1.00 169.67 ? 25  CYS B N   1 
ATOM 1934 C CA  . CYS B 2 35  ? 72.539  127.306 62.224  1.00 168.59 ? 25  CYS B CA  1 
ATOM 1935 C C   . CYS B 2 35  ? 72.194  126.905 63.652  1.00 168.95 ? 25  CYS B C   1 
ATOM 1936 O O   . CYS B 2 35  ? 71.969  125.718 63.909  1.00 169.07 ? 25  CYS B O   1 
ATOM 1937 C CB  . CYS B 2 35  ? 73.717  126.463 61.723  1.00 168.28 ? 25  CYS B CB  1 
ATOM 1938 S SG  . CYS B 2 35  ? 75.263  126.714 62.625  1.00 171.09 ? 25  CYS B SG  1 
ATOM 1939 N N   . ALA B 2 36  ? 72.143  127.857 64.582  1.00 166.30 ? 26  ALA B N   1 
ATOM 1940 C CA  . ALA B 2 36  ? 71.763  127.574 65.966  1.00 165.69 ? 26  ALA B CA  1 
ATOM 1941 C C   . ALA B 2 36  ? 70.243  127.640 66.126  1.00 166.39 ? 26  ALA B C   1 
ATOM 1942 O O   . ALA B 2 36  ? 69.696  128.396 66.929  1.00 166.16 ? 26  ALA B O   1 
ATOM 1943 C CB  . ALA B 2 36  ? 72.466  128.538 66.915  1.00 164.27 ? 26  ALA B CB  1 
ATOM 1944 N N   . ASP B 2 37  ? 69.560  126.820 65.324  1.00 166.07 ? 27  ASP B N   1 
ATOM 1945 C CA  . ASP B 2 37  ? 68.100  126.805 65.341  1.00 165.61 ? 27  ASP B CA  1 
ATOM 1946 C C   . ASP B 2 37  ? 67.560  126.303 66.675  1.00 165.31 ? 27  ASP B C   1 
ATOM 1947 O O   . ASP B 2 37  ? 66.581  126.849 67.198  1.00 165.56 ? 27  ASP B O   1 
ATOM 1948 C CB  . ASP B 2 37  ? 67.573  125.949 64.189  1.00 165.36 ? 27  ASP B CB  1 
ATOM 1949 C CG  . ASP B 2 37  ? 68.211  124.574 64.143  1.00 165.14 ? 27  ASP B CG  1 
ATOM 1950 O OD1 . ASP B 2 37  ? 69.131  124.314 64.947  1.00 164.86 ? 27  ASP B OD1 1 
ATOM 1951 O OD2 . ASP B 2 37  ? 67.792  123.751 63.301  1.00 164.57 ? 27  ASP B OD2 1 
ATOM 1952 N N   . ALA B 2 38  ? 68.179  125.270 67.240  1.00 163.65 ? 28  ALA B N   1 
ATOM 1953 C CA  . ALA B 2 38  ? 67.728  124.662 68.483  1.00 164.30 ? 28  ALA B CA  1 
ATOM 1954 C C   . ALA B 2 38  ? 68.912  124.516 69.433  1.00 164.57 ? 28  ALA B C   1 
ATOM 1955 O O   . ALA B 2 38  ? 70.055  124.835 69.094  1.00 163.98 ? 28  ALA B O   1 
ATOM 1956 C CB  . ALA B 2 38  ? 67.061  123.305 68.226  1.00 162.94 ? 28  ALA B CB  1 
ATOM 1957 N N   . THR B 2 39  ? 68.627  124.026 70.637  1.00 158.95 ? 29  THR B N   1 
ATOM 1958 C CA  . THR B 2 39  ? 69.642  123.765 71.645  1.00 158.68 ? 29  THR B CA  1 
ATOM 1959 C C   . THR B 2 39  ? 69.698  122.273 71.948  1.00 157.99 ? 29  THR B C   1 
ATOM 1960 O O   . THR B 2 39  ? 68.677  121.578 71.918  1.00 157.28 ? 29  THR B O   1 
ATOM 1961 C CB  . THR B 2 39  ? 69.358  124.550 72.936  1.00 156.94 ? 29  THR B CB  1 
ATOM 1962 O OG1 . THR B 2 39  ? 69.029  125.906 72.609  1.00 157.05 ? 29  THR B OG1 1 
ATOM 1963 C CG2 . THR B 2 39  ? 70.574  124.544 73.851  1.00 155.31 ? 29  THR B CG2 1 
ATOM 1964 N N   . LEU B 2 40  ? 70.910  121.786 72.230  1.00 145.80 ? 30  LEU B N   1 
ATOM 1965 C CA  . LEU B 2 40  ? 71.085  120.394 72.635  1.00 145.63 ? 30  LEU B CA  1 
ATOM 1966 C C   . LEU B 2 40  ? 70.264  120.067 73.878  1.00 144.99 ? 30  LEU B C   1 
ATOM 1967 O O   . LEU B 2 40  ? 69.756  118.948 74.018  1.00 143.67 ? 30  LEU B O   1 
ATOM 1968 C CB  . LEU B 2 40  ? 72.567  120.103 72.874  1.00 144.51 ? 30  LEU B CB  1 
ATOM 1969 C CG  . LEU B 2 40  ? 72.939  118.710 73.388  1.00 144.39 ? 30  LEU B CG  1 
ATOM 1970 C CD1 . LEU B 2 40  ? 72.407  117.626 72.467  1.00 143.93 ? 30  LEU B CD1 1 
ATOM 1971 C CD2 . LEU B 2 40  ? 74.447  118.585 73.550  1.00 142.31 ? 30  LEU B CD2 1 
ATOM 1972 N N   . SER B 2 41  ? 70.128  121.029 74.794  1.00 147.88 ? 31  SER B N   1 
ATOM 1973 C CA  . SER B 2 41  ? 69.300  120.812 75.977  1.00 147.90 ? 31  SER B CA  1 
ATOM 1974 C C   . SER B 2 41  ? 67.844  120.572 75.598  1.00 149.37 ? 31  SER B C   1 
ATOM 1975 O O   . SER B 2 41  ? 67.186  119.688 76.160  1.00 149.52 ? 31  SER B O   1 
ATOM 1976 C CB  . SER B 2 41  ? 69.418  122.006 76.925  1.00 147.19 ? 31  SER B CB  1 
ATOM 1977 O OG  . SER B 2 41  ? 68.611  121.824 78.076  1.00 147.09 ? 31  SER B OG  1 
ATOM 1978 N N   . GLN B 2 42  ? 67.320  121.354 74.651  1.00 151.84 ? 32  GLN B N   1 
ATOM 1979 C CA  . GLN B 2 42  ? 65.945  121.151 74.204  1.00 151.57 ? 32  GLN B CA  1 
ATOM 1980 C C   . GLN B 2 42  ? 65.782  119.807 73.504  1.00 151.27 ? 32  GLN B C   1 
ATOM 1981 O O   . GLN B 2 42  ? 64.755  119.138 73.665  1.00 150.76 ? 32  GLN B O   1 
ATOM 1982 C CB  . GLN B 2 42  ? 65.518  122.292 73.280  1.00 151.03 ? 32  GLN B CB  1 
ATOM 1983 C CG  . GLN B 2 42  ? 65.563  123.668 73.923  1.00 150.97 ? 32  GLN B CG  1 
ATOM 1984 C CD  . GLN B 2 42  ? 65.126  124.766 72.973  1.00 150.03 ? 32  GLN B CD  1 
ATOM 1985 O OE1 . GLN B 2 42  ? 64.743  124.501 71.834  1.00 149.73 ? 32  GLN B OE1 1 
ATOM 1986 N NE2 . GLN B 2 42  ? 65.178  126.008 73.440  1.00 149.79 ? 32  GLN B NE2 1 
ATOM 1987 N N   . ILE B 2 43  ? 66.780  119.401 72.715  1.00 146.72 ? 33  ILE B N   1 
ATOM 1988 C CA  . ILE B 2 43  ? 66.679  118.151 71.969  1.00 146.84 ? 33  ILE B CA  1 
ATOM 1989 C C   . ILE B 2 43  ? 66.639  116.958 72.917  1.00 146.84 ? 33  ILE B C   1 
ATOM 1990 O O   . ILE B 2 43  ? 65.859  116.018 72.721  1.00 145.34 ? 33  ILE B O   1 
ATOM 1991 C CB  . ILE B 2 43  ? 67.839  118.037 70.962  1.00 145.69 ? 33  ILE B CB  1 
ATOM 1992 C CG1 . ILE B 2 43  ? 67.754  119.157 69.922  1.00 145.64 ? 33  ILE B CG1 1 
ATOM 1993 C CG2 . ILE B 2 43  ? 67.828  116.677 70.280  1.00 144.54 ? 33  ILE B CG2 1 
ATOM 1994 C CD1 . ILE B 2 43  ? 66.479  119.139 69.107  1.00 145.64 ? 33  ILE B CD1 1 
ATOM 1995 N N   . THR B 2 44  ? 67.465  116.976 73.963  1.00 145.57 ? 34  THR B N   1 
ATOM 1996 C CA  . THR B 2 44  ? 67.589  115.847 74.875  1.00 144.31 ? 34  THR B CA  1 
ATOM 1997 C C   . THR B 2 44  ? 66.744  116.018 76.134  1.00 142.85 ? 34  THR B C   1 
ATOM 1998 O O   . THR B 2 44  ? 66.985  115.331 77.132  1.00 141.45 ? 34  THR B O   1 
ATOM 1999 C CB  . THR B 2 44  ? 69.055  115.630 75.253  1.00 143.84 ? 34  THR B CB  1 
ATOM 2000 O OG1 . THR B 2 44  ? 69.569  116.811 75.880  1.00 141.62 ? 34  THR B OG1 1 
ATOM 2001 C CG2 . THR B 2 44  ? 69.882  115.319 74.015  1.00 143.66 ? 34  THR B CG2 1 
ATOM 2002 N N   . ASN B 2 45  ? 65.769  116.928 76.110  1.00 149.32 ? 35  ASN B N   1 
ATOM 2003 C CA  . ASN B 2 45  ? 64.894  117.103 77.265  1.00 150.68 ? 35  ASN B CA  1 
ATOM 2004 C C   . ASN B 2 45  ? 63.971  115.905 77.448  1.00 151.21 ? 35  ASN B C   1 
ATOM 2005 O O   . ASN B 2 45  ? 63.684  115.499 78.581  1.00 149.98 ? 35  ASN B O   1 
ATOM 2006 C CB  . ASN B 2 45  ? 64.083  118.390 77.119  1.00 150.07 ? 35  ASN B CB  1 
ATOM 2007 C CG  . ASN B 2 45  ? 63.219  118.676 78.332  1.00 149.02 ? 35  ASN B CG  1 
ATOM 2008 O OD1 . ASN B 2 45  ? 63.534  118.256 79.446  1.00 146.97 ? 35  ASN B OD1 1 
ATOM 2009 N ND2 . ASN B 2 45  ? 62.122  119.393 78.122  1.00 149.09 ? 35  ASN B ND2 1 
ATOM 2010 N N   . ASN B 2 46  ? 63.495  115.326 76.342  1.00 157.43 ? 36  ASN B N   1 
ATOM 2011 C CA  . ASN B 2 46  ? 62.509  114.253 76.419  1.00 157.60 ? 36  ASN B CA  1 
ATOM 2012 C C   . ASN B 2 46  ? 63.104  112.952 76.943  1.00 157.04 ? 36  ASN B C   1 
ATOM 2013 O O   . ASN B 2 46  ? 62.410  112.194 77.630  1.00 157.09 ? 36  ASN B O   1 
ATOM 2014 C CB  . ASN B 2 46  ? 61.876  114.027 75.046  1.00 157.33 ? 36  ASN B CB  1 
ATOM 2015 C CG  . ASN B 2 46  ? 61.186  115.266 74.512  1.00 157.15 ? 36  ASN B CG  1 
ATOM 2016 O OD1 . ASN B 2 46  ? 61.463  116.383 74.949  1.00 157.59 ? 36  ASN B OD1 1 
ATOM 2017 N ND2 . ASN B 2 46  ? 60.280  115.075 73.559  1.00 156.74 ? 36  ASN B ND2 1 
ATOM 2018 N N   . ILE B 2 47  ? 64.370  112.668 76.629  1.00 140.33 ? 37  ILE B N   1 
ATOM 2019 C CA  . ILE B 2 47  ? 64.951  111.382 76.995  1.00 138.93 ? 37  ILE B CA  1 
ATOM 2020 C C   . ILE B 2 47  ? 65.066  111.273 78.512  1.00 138.06 ? 37  ILE B C   1 
ATOM 2021 O O   . ILE B 2 47  ? 65.239  112.271 79.225  1.00 137.24 ? 37  ILE B O   1 
ATOM 2022 C CB  . ILE B 2 47  ? 66.320  111.182 76.319  1.00 138.46 ? 37  ILE B CB  1 
ATOM 2023 C CG1 . ILE B 2 47  ? 67.344  112.179 76.864  1.00 137.00 ? 37  ILE B CG1 1 
ATOM 2024 C CG2 . ILE B 2 47  ? 66.191  111.316 74.811  1.00 137.58 ? 37  ILE B CG2 1 
ATOM 2025 C CD1 . ILE B 2 47  ? 68.729  112.008 76.285  1.00 136.29 ? 37  ILE B CD1 1 
ATOM 2026 N N   . ASP B 2 48  ? 64.954  110.045 79.010  1.00 134.56 ? 38  ASP B N   1 
ATOM 2027 C CA  . ASP B 2 48  ? 65.026  109.813 80.441  1.00 136.03 ? 38  ASP B CA  1 
ATOM 2028 C C   . ASP B 2 48  ? 66.462  109.969 80.941  1.00 135.03 ? 38  ASP B C   1 
ATOM 2029 O O   . ASP B 2 48  ? 67.418  109.715 80.203  1.00 133.47 ? 38  ASP B O   1 
ATOM 2030 C CB  . ASP B 2 48  ? 64.510  108.417 80.779  1.00 135.86 ? 38  ASP B CB  1 
ATOM 2031 C CG  . ASP B 2 48  ? 63.085  108.194 80.313  1.00 136.23 ? 38  ASP B CG  1 
ATOM 2032 O OD1 . ASP B 2 48  ? 62.318  109.178 80.252  1.00 136.63 ? 38  ASP B OD1 1 
ATOM 2033 O OD2 . ASP B 2 48  ? 62.732  107.036 80.007  1.00 135.16 ? 38  ASP B OD2 1 
ATOM 2034 N N   . PRO B 2 49  ? 66.639  110.390 82.190  1.00 120.15 ? 39  PRO B N   1 
ATOM 2035 C CA  . PRO B 2 49  ? 67.990  110.496 82.747  1.00 117.16 ? 39  PRO B CA  1 
ATOM 2036 C C   . PRO B 2 49  ? 68.584  109.123 83.019  1.00 117.22 ? 39  PRO B C   1 
ATOM 2037 O O   . PRO B 2 49  ? 67.882  108.114 83.117  1.00 118.07 ? 39  PRO B O   1 
ATOM 2038 C CB  . PRO B 2 49  ? 67.779  111.276 84.049  1.00 115.91 ? 39  PRO B CB  1 
ATOM 2039 C CG  . PRO B 2 49  ? 66.369  110.978 84.431  1.00 115.92 ? 39  PRO B CG  1 
ATOM 2040 C CD  . PRO B 2 49  ? 65.612  110.859 83.137  1.00 118.30 ? 39  PRO B CD  1 
ATOM 2041 N N   . VAL B 2 50  ? 69.914  109.096 83.140  1.00 105.94 ? 40  VAL B N   1 
ATOM 2042 C CA  . VAL B 2 50  ? 70.611  107.854 83.449  1.00 105.39 ? 40  VAL B CA  1 
ATOM 2043 C C   . VAL B 2 50  ? 70.436  107.424 84.896  1.00 107.30 ? 40  VAL B C   1 
ATOM 2044 O O   . VAL B 2 50  ? 70.856  106.318 85.256  1.00 108.64 ? 40  VAL B O   1 
ATOM 2045 C CB  . VAL B 2 50  ? 72.117  107.974 83.137  1.00 101.90 ? 40  VAL B CB  1 
ATOM 2046 C CG1 . VAL B 2 50  ? 72.331  108.343 81.679  1.00 103.45 ? 40  VAL B CG1 1 
ATOM 2047 C CG2 . VAL B 2 50  ? 72.770  108.994 84.056  1.00 100.37 ? 40  VAL B CG2 1 
ATOM 2048 N N   . GLY B 2 51  ? 69.829  108.260 85.734  1.00 114.53 ? 41  GLY B N   1 
ATOM 2049 C CA  . GLY B 2 51  ? 69.718  107.937 87.140  1.00 113.80 ? 41  GLY B CA  1 
ATOM 2050 C C   . GLY B 2 51  ? 71.020  108.211 87.872  1.00 114.60 ? 41  GLY B C   1 
ATOM 2051 O O   . GLY B 2 51  ? 71.875  108.981 87.422  1.00 115.23 ? 41  GLY B O   1 
ATOM 2052 N N   . ARG B 2 52  ? 71.166  107.566 89.026  1.00 108.42 ? 42  ARG B N   1 
ATOM 2053 C CA  . ARG B 2 52  ? 72.387  107.679 89.810  1.00 107.94 ? 42  ARG B CA  1 
ATOM 2054 C C   . ARG B 2 52  ? 73.352  106.585 89.374  1.00 106.98 ? 42  ARG B C   1 
ATOM 2055 O O   . ARG B 2 52  ? 72.993  105.403 89.355  1.00 106.07 ? 42  ARG B O   1 
ATOM 2056 C CB  . ARG B 2 52  ? 72.081  107.559 91.303  1.00 105.58 ? 42  ARG B CB  1 
ATOM 2057 C CG  . ARG B 2 52  ? 73.225  107.963 92.220  1.00 104.43 ? 42  ARG B CG  1 
ATOM 2058 C CD  . ARG B 2 52  ? 73.556  109.441 92.080  1.00 108.48 ? 42  ARG B CD  1 
ATOM 2059 N NE  . ARG B 2 52  ? 74.611  109.852 92.999  1.00 112.02 ? 42  ARG B NE  1 
ATOM 2060 C CZ  . ARG B 2 52  ? 75.069  111.091 93.107  1.00 111.33 ? 42  ARG B CZ  1 
ATOM 2061 N NH1 . ARG B 2 52  ? 74.586  112.074 92.365  1.00 108.41 ? 42  ARG B NH1 1 
ATOM 2062 N NH2 . ARG B 2 52  ? 76.035  111.352 93.983  1.00 109.96 ? 42  ARG B NH2 1 
ATOM 2063 N N   . ILE B 2 53  ? 74.572  106.980 89.028  1.00 97.30  ? 43  ILE B N   1 
ATOM 2064 C CA  . ILE B 2 53  ? 75.610  106.048 88.606  1.00 93.92  ? 43  ILE B CA  1 
ATOM 2065 C C   . ILE B 2 53  ? 76.506  105.763 89.802  1.00 92.46  ? 43  ILE B C   1 
ATOM 2066 O O   . ILE B 2 53  ? 77.224  106.648 90.281  1.00 95.25  ? 43  ILE B O   1 
ATOM 2067 C CB  . ILE B 2 53  ? 76.414  106.596 87.420  1.00 94.76  ? 43  ILE B CB  1 
ATOM 2068 C CG1 . ILE B 2 53  ? 75.520  106.720 86.184  1.00 93.50  ? 43  ILE B CG1 1 
ATOM 2069 C CG2 . ILE B 2 53  ? 77.611  105.704 87.132  1.00 91.88  ? 43  ILE B CG2 1 
ATOM 2070 C CD1 . ILE B 2 53  ? 74.898  105.414 85.744  1.00 90.30  ? 43  ILE B CD1 1 
ATOM 2071 N N   . GLN B 2 54  ? 76.464  104.528 90.288  1.00 88.56  ? 44  GLN B N   1 
ATOM 2072 C CA  . GLN B 2 54  ? 77.266  104.093 91.422  1.00 88.84  ? 44  GLN B CA  1 
ATOM 2073 C C   . GLN B 2 54  ? 78.337  103.136 90.918  1.00 91.01  ? 44  GLN B C   1 
ATOM 2074 O O   . GLN B 2 54  ? 78.017  102.083 90.356  1.00 95.22  ? 44  GLN B O   1 
ATOM 2075 C CB  . GLN B 2 54  ? 76.398  103.424 92.488  1.00 93.78  ? 44  GLN B CB  1 
ATOM 2076 C CG  . GLN B 2 54  ? 75.349  104.340 93.101  1.00 94.86  ? 44  GLN B CG  1 
ATOM 2077 C CD  . GLN B 2 54  ? 75.947  105.366 94.045  1.00 94.36  ? 44  GLN B CD  1 
ATOM 2078 O OE1 . GLN B 2 54  ? 77.127  105.299 94.390  1.00 95.34  ? 44  GLN B OE1 1 
ATOM 2079 N NE2 . GLN B 2 54  ? 75.132  106.325 94.470  1.00 90.81  ? 44  GLN B NE2 1 
ATOM 2080 N N   . MET B 2 55  ? 79.599  103.499 91.120  1.00 71.01  ? 45  MET B N   1 
ATOM 2081 C CA  . MET B 2 55  ? 80.722  102.655 90.743  1.00 69.39  ? 45  MET B CA  1 
ATOM 2082 C C   . MET B 2 55  ? 81.584  102.384 91.966  1.00 66.11  ? 45  MET B C   1 
ATOM 2083 O O   . MET B 2 55  ? 81.849  103.287 92.766  1.00 70.49  ? 45  MET B O   1 
ATOM 2084 C CB  . MET B 2 55  ? 81.567  103.304 89.641  1.00 65.01  ? 45  MET B CB  1 
ATOM 2085 C CG  . MET B 2 55  ? 80.824  103.531 88.334  1.00 67.60  ? 45  MET B CG  1 
ATOM 2086 S SD  . MET B 2 55  ? 81.867  104.289 87.071  1.00 82.64  ? 45  MET B SD  1 
ATOM 2087 C CE  . MET B 2 55  ? 80.729  104.369 85.690  1.00 78.10  ? 45  MET B CE  1 
ATOM 2088 N N   . ARG B 2 56  ? 82.015  101.136 92.105  1.00 53.00  ? 46  ARG B N   1 
ATOM 2089 C CA  . ARG B 2 56  ? 82.867  100.715 93.204  1.00 55.79  ? 46  ARG B CA  1 
ATOM 2090 C C   . ARG B 2 56  ? 84.275  100.446 92.692  1.00 49.29  ? 46  ARG B C   1 
ATOM 2091 O O   . ARG B 2 56  ? 84.477  100.119 91.519  1.00 56.73  ? 46  ARG B O   1 
ATOM 2092 C CB  . ARG B 2 56  ? 82.312  99.463  93.889  1.00 61.31  ? 46  ARG B CB  1 
ATOM 2093 C CG  . ARG B 2 56  ? 80.918  99.641  94.469  1.00 65.89  ? 46  ARG B CG  1 
ATOM 2094 C CD  . ARG B 2 56  ? 80.456  98.396  95.212  1.00 61.82  ? 46  ARG B CD  1 
ATOM 2095 N NE  . ARG B 2 56  ? 81.240  98.155  96.418  1.00 63.20  ? 46  ARG B NE  1 
ATOM 2096 C CZ  . ARG B 2 56  ? 82.228  97.275  96.509  1.00 68.41  ? 46  ARG B CZ  1 
ATOM 2097 N NH1 . ARG B 2 56  ? 82.580  96.523  95.480  1.00 68.91  ? 46  ARG B NH1 1 
ATOM 2098 N NH2 . ARG B 2 56  ? 82.880  97.149  97.662  1.00 65.59  ? 46  ARG B NH2 1 
ATOM 2099 N N   . THR B 2 57  ? 85.249  100.593 93.585  1.00 44.86  ? 47  THR B N   1 
ATOM 2100 C CA  . THR B 2 57  ? 86.640  100.293 93.263  1.00 41.95  ? 47  THR B CA  1 
ATOM 2101 C C   . THR B 2 57  ? 86.821  98.781  93.247  1.00 52.92  ? 47  THR B C   1 
ATOM 2102 O O   . THR B 2 57  ? 86.907  98.140  94.296  1.00 66.35  ? 47  THR B O   1 
ATOM 2103 C CB  . THR B 2 57  ? 87.572  100.950 94.275  1.00 46.30  ? 47  THR B CB  1 
ATOM 2104 O OG1 . THR B 2 57  ? 87.398  102.372 94.234  1.00 50.38  ? 47  THR B OG1 1 
ATOM 2105 C CG2 . THR B 2 57  ? 89.019  100.618 93.965  1.00 43.45  ? 47  THR B CG2 1 
ATOM 2106 N N   . ARG B 2 58  ? 86.876  98.204  92.045  1.00 61.39  ? 48  ARG B N   1 
ATOM 2107 C CA  . ARG B 2 58  ? 87.123  96.772  91.925  1.00 62.68  ? 48  ARG B CA  1 
ATOM 2108 C C   . ARG B 2 58  ? 88.592  96.446  92.160  1.00 63.88  ? 48  ARG B C   1 
ATOM 2109 O O   . ARG B 2 58  ? 88.916  95.439  92.797  1.00 64.81  ? 48  ARG B O   1 
ATOM 2110 C CB  . ARG B 2 58  ? 86.677  96.271  90.552  1.00 61.19  ? 48  ARG B CB  1 
ATOM 2111 C CG  . ARG B 2 58  ? 85.224  96.564  90.233  1.00 68.61  ? 48  ARG B CG  1 
ATOM 2112 C CD  . ARG B 2 58  ? 84.299  95.921  91.249  1.00 69.30  ? 48  ARG B CD  1 
ATOM 2113 N NE  . ARG B 2 58  ? 82.897  96.195  90.956  1.00 71.86  ? 48  ARG B NE  1 
ATOM 2114 C CZ  . ARG B 2 58  ? 81.880  95.747  91.679  1.00 74.35  ? 48  ARG B CZ  1 
ATOM 2115 N NH1 . ARG B 2 58  ? 82.073  94.994  92.750  1.00 72.09  ? 48  ARG B NH1 1 
ATOM 2116 N NH2 . ARG B 2 58  ? 80.639  96.059  91.317  1.00 72.89  ? 48  ARG B NH2 1 
ATOM 2117 N N   . ARG B 2 59  ? 89.487  97.289  91.656  1.00 52.87  ? 49  ARG B N   1 
ATOM 2118 C CA  . ARG B 2 59  ? 90.922  97.086  91.773  1.00 51.94  ? 49  ARG B CA  1 
ATOM 2119 C C   . ARG B 2 59  ? 91.566  98.393  92.207  1.00 55.13  ? 49  ARG B C   1 
ATOM 2120 O O   . ARG B 2 59  ? 91.110  99.479  91.842  1.00 60.01  ? 49  ARG B O   1 
ATOM 2121 C CB  . ARG B 2 59  ? 91.550  96.612  90.454  1.00 53.57  ? 49  ARG B CB  1 
ATOM 2122 C CG  . ARG B 2 59  ? 90.935  95.352  89.864  1.00 55.02  ? 49  ARG B CG  1 
ATOM 2123 C CD  . ARG B 2 59  ? 91.130  94.151  90.770  1.00 52.11  ? 49  ARG B CD  1 
ATOM 2124 N NE  . ARG B 2 59  ? 90.882  92.898  90.068  1.00 53.79  ? 49  ARG B NE  1 
ATOM 2125 C CZ  . ARG B 2 59  ? 89.692  92.325  89.954  1.00 64.10  ? 49  ARG B CZ  1 
ATOM 2126 N NH1 . ARG B 2 59  ? 88.611  92.868  90.488  1.00 69.32  ? 49  ARG B NH1 1 
ATOM 2127 N NH2 . ARG B 2 59  ? 89.584  91.180  89.287  1.00 66.05  ? 49  ARG B NH2 1 
ATOM 2128 N N   . THR B 2 60  ? 92.642  98.277  92.978  1.00 55.94  ? 50  THR B N   1 
ATOM 2129 C CA  . THR B 2 60  ? 93.499  99.408  93.306  1.00 53.75  ? 50  THR B CA  1 
ATOM 2130 C C   . THR B 2 60  ? 94.915  99.073  92.868  1.00 49.50  ? 50  THR B C   1 
ATOM 2131 O O   . THR B 2 60  ? 95.493  98.082  93.327  1.00 50.60  ? 50  THR B O   1 
ATOM 2132 C CB  . THR B 2 60  ? 93.458  99.722  94.803  1.00 56.24  ? 50  THR B CB  1 
ATOM 2133 O OG1 . THR B 2 60  ? 92.135  100.128 95.173  1.00 61.91  ? 50  THR B OG1 1 
ATOM 2134 C CG2 . THR B 2 60  ? 94.436  100.837 95.139  1.00 49.71  ? 50  THR B CG2 1 
ATOM 2135 N N   . LEU B 2 61  ? 95.467  99.895  91.981  1.00 35.64  ? 51  LEU B N   1 
ATOM 2136 C CA  . LEU B 2 61  ? 96.802  99.672  91.441  1.00 41.15  ? 51  LEU B CA  1 
ATOM 2137 C C   . LEU B 2 61  ? 97.796  100.464 92.280  1.00 45.11  ? 51  LEU B C   1 
ATOM 2138 O O   . LEU B 2 61  ? 97.800  101.699 92.254  1.00 54.23  ? 51  LEU B O   1 
ATOM 2139 C CB  . LEU B 2 61  ? 96.859  100.081 89.972  1.00 38.80  ? 51  LEU B CB  1 
ATOM 2140 C CG  . LEU B 2 61  ? 95.768  99.493  89.074  1.00 38.10  ? 51  LEU B CG  1 
ATOM 2141 C CD1 . LEU B 2 61  ? 95.951  99.937  87.630  1.00 42.13  ? 51  LEU B CD1 1 
ATOM 2142 C CD2 . LEU B 2 61  ? 95.747  97.978  89.172  1.00 47.30  ? 51  LEU B CD2 1 
ATOM 2143 N N   . ARG B 2 62  ? 98.632  99.752  93.026  1.00 46.62  ? 52  ARG B N   1 
ATOM 2144 C CA  . ARG B 2 62  ? 99.606  100.352 93.921  1.00 50.57  ? 52  ARG B CA  1 
ATOM 2145 C C   . ARG B 2 62  ? 101.014 100.105 93.400  1.00 54.37  ? 52  ARG B C   1 
ATOM 2146 O O   . ARG B 2 62  ? 101.296 99.073  92.787  1.00 57.17  ? 52  ARG B O   1 
ATOM 2147 C CB  . ARG B 2 62  ? 99.473  99.788  95.339  1.00 52.72  ? 52  ARG B CB  1 
ATOM 2148 C CG  . ARG B 2 62  ? 98.064  99.861  95.898  1.00 55.21  ? 52  ARG B CG  1 
ATOM 2149 C CD  . ARG B 2 62  ? 97.982  99.236  97.280  1.00 55.85  ? 52  ARG B CD  1 
ATOM 2150 N NE  . ARG B 2 62  ? 96.609  99.184  97.769  1.00 54.44  ? 52  ARG B NE  1 
ATOM 2151 C CZ  . ARG B 2 62  ? 96.030  100.143 98.477  1.00 55.96  ? 52  ARG B CZ  1 
ATOM 2152 N NH1 . ARG B 2 62  ? 96.680  101.247 98.808  1.00 58.02  ? 52  ARG B NH1 1 
ATOM 2153 N NH2 . ARG B 2 62  ? 94.767  99.990  98.865  1.00 52.28  ? 52  ARG B NH2 1 
ATOM 2154 N N   . GLY B 2 63  ? 101.898 101.063 93.658  1.00 53.89  ? 53  GLY B N   1 
ATOM 2155 C CA  . GLY B 2 63  ? 103.270 100.959 93.206  1.00 55.26  ? 53  GLY B CA  1 
ATOM 2156 C C   . GLY B 2 63  ? 103.866 102.272 92.751  1.00 56.81  ? 53  GLY B C   1 
ATOM 2157 O O   . GLY B 2 63  ? 105.076 102.479 92.874  1.00 64.96  ? 53  GLY B O   1 
ATOM 2158 N N   . HIS B 2 64  ? 103.037 103.169 92.225  1.00 44.75  ? 54  HIS B N   1 
ATOM 2159 C CA  . HIS B 2 64  ? 103.492 104.531 91.995  1.00 40.54  ? 54  HIS B CA  1 
ATOM 2160 C C   . HIS B 2 64  ? 103.736 105.218 93.334  1.00 37.81  ? 54  HIS B C   1 
ATOM 2161 O O   . HIS B 2 64  ? 102.915 105.121 94.251  1.00 47.20  ? 54  HIS B O   1 
ATOM 2162 C CB  . HIS B 2 64  ? 102.460 105.295 91.169  1.00 42.01  ? 54  HIS B CB  1 
ATOM 2163 C CG  . HIS B 2 64  ? 102.344 104.809 89.758  1.00 43.05  ? 54  HIS B CG  1 
ATOM 2164 N ND1 . HIS B 2 64  ? 103.331 105.009 88.818  1.00 38.73  ? 54  HIS B ND1 1 
ATOM 2165 C CD2 . HIS B 2 64  ? 101.362 104.120 89.130  1.00 43.52  ? 54  HIS B CD2 1 
ATOM 2166 C CE1 . HIS B 2 64  ? 102.959 104.472 87.670  1.00 46.65  ? 54  HIS B CE1 1 
ATOM 2167 N NE2 . HIS B 2 64  ? 101.767 103.926 87.832  1.00 49.04  ? 54  HIS B NE2 1 
ATOM 2168 N N   . LEU B 2 65  ? 104.875 105.898 93.453  1.00 52.58  ? 55  LEU B N   1 
ATOM 2169 C CA  . LEU B 2 65  ? 105.280 106.549 94.694  1.00 58.32  ? 55  LEU B CA  1 
ATOM 2170 C C   . LEU B 2 65  ? 105.280 108.069 94.583  1.00 63.25  ? 55  LEU B C   1 
ATOM 2171 O O   . LEU B 2 65  ? 105.859 108.752 95.434  1.00 68.05  ? 55  LEU B O   1 
ATOM 2172 C CB  . LEU B 2 65  ? 106.642 106.023 95.142  1.00 55.73  ? 55  LEU B CB  1 
ATOM 2173 C CG  . LEU B 2 65  ? 106.576 104.504 95.294  1.00 56.11  ? 55  LEU B CG  1 
ATOM 2174 C CD1 . LEU B 2 65  ? 107.922 103.910 95.627  1.00 58.79  ? 55  LEU B CD1 1 
ATOM 2175 C CD2 . LEU B 2 65  ? 105.557 104.150 96.365  1.00 56.13  ? 55  LEU B CD2 1 
ATOM 2176 N N   . ALA B 2 66  ? 104.642 108.609 93.551  1.00 53.28  ? 56  ALA B N   1 
ATOM 2177 C CA  . ALA B 2 66  ? 104.543 110.046 93.345  1.00 50.29  ? 56  ALA B CA  1 
ATOM 2178 C C   . ALA B 2 66  ? 103.248 110.316 92.592  1.00 41.29  ? 56  ALA B C   1 
ATOM 2179 O O   . ALA B 2 66  ? 102.447 109.406 92.361  1.00 44.42  ? 56  ALA B O   1 
ATOM 2180 C CB  . ALA B 2 66  ? 105.776 110.581 92.607  1.00 45.00  ? 56  ALA B CB  1 
ATOM 2181 N N   . LYS B 2 67  ? 103.036 111.572 92.210  1.00 43.22  ? 57  LYS B N   1 
ATOM 2182 C CA  . LYS B 2 67  ? 101.812 111.918 91.503  1.00 43.02  ? 57  LYS B CA  1 
ATOM 2183 C C   . LYS B 2 67  ? 101.752 111.187 90.169  1.00 53.30  ? 57  LYS B C   1 
ATOM 2184 O O   . LYS B 2 67  ? 102.729 111.159 89.415  1.00 62.37  ? 57  LYS B O   1 
ATOM 2185 C CB  . LYS B 2 67  ? 101.740 113.430 91.284  1.00 51.00  ? 57  LYS B CB  1 
ATOM 2186 C CG  . LYS B 2 67  ? 101.847 114.259 92.559  1.00 54.47  ? 57  LYS B CG  1 
ATOM 2187 C CD  . LYS B 2 67  ? 103.269 114.756 92.783  1.00 51.35  ? 57  LYS B CD  1 
ATOM 2188 C CE  . LYS B 2 67  ? 103.688 115.727 91.692  1.00 46.93  ? 57  LYS B CE  1 
ATOM 2189 N NZ  . LYS B 2 67  ? 105.058 116.263 91.910  1.00 54.98  ? 57  LYS B NZ  1 
ATOM 2190 N N   . ILE B 2 68  ? 100.596 110.601 89.879  1.00 44.92  ? 58  ILE B N   1 
ATOM 2191 C CA  . ILE B 2 68  ? 100.316 110.016 88.574  1.00 39.15  ? 58  ILE B CA  1 
ATOM 2192 C C   . ILE B 2 68  ? 99.753  111.106 87.678  1.00 41.06  ? 58  ILE B C   1 
ATOM 2193 O O   . ILE B 2 68  ? 98.813  111.808 88.064  1.00 45.39  ? 58  ILE B O   1 
ATOM 2194 C CB  . ILE B 2 68  ? 99.334  108.841 88.697  1.00 36.59  ? 58  ILE B CB  1 
ATOM 2195 C CG1 . ILE B 2 68  ? 99.935  107.729 89.559  1.00 40.38  ? 58  ILE B CG1 1 
ATOM 2196 C CG2 . ILE B 2 68  ? 98.952  108.317 87.322  1.00 43.06  ? 58  ILE B CG2 1 
ATOM 2197 C CD1 . ILE B 2 68  ? 99.013  106.550 89.764  1.00 46.30  ? 58  ILE B CD1 1 
ATOM 2198 N N   . TYR B 2 69  ? 100.335 111.267 86.489  1.00 43.43  ? 59  TYR B N   1 
ATOM 2199 C CA  . TYR B 2 69  ? 99.908  112.326 85.589  1.00 44.73  ? 59  TYR B CA  1 
ATOM 2200 C C   . TYR B 2 69  ? 99.164  111.842 84.353  1.00 49.64  ? 59  TYR B C   1 
ATOM 2201 O O   . TYR B 2 69  ? 98.418  112.629 83.761  1.00 50.29  ? 59  TYR B O   1 
ATOM 2202 C CB  . TYR B 2 69  ? 101.115 113.166 85.148  1.00 44.03  ? 59  TYR B CB  1 
ATOM 2203 C CG  . TYR B 2 69  ? 101.247 114.450 85.929  1.00 38.11  ? 59  TYR B CG  1 
ATOM 2204 C CD1 . TYR B 2 69  ? 101.709 114.441 87.237  1.00 29.29  ? 59  TYR B CD1 1 
ATOM 2205 C CD2 . TYR B 2 69  ? 100.896 115.668 85.368  1.00 50.48  ? 59  TYR B CD2 1 
ATOM 2206 C CE1 . TYR B 2 69  ? 101.824 115.609 87.961  1.00 40.59  ? 59  TYR B CE1 1 
ATOM 2207 C CE2 . TYR B 2 69  ? 101.010 116.842 86.084  1.00 44.28  ? 59  TYR B CE2 1 
ATOM 2208 C CZ  . TYR B 2 69  ? 101.475 116.807 87.380  1.00 47.82  ? 59  TYR B CZ  1 
ATOM 2209 O OH  . TYR B 2 69  ? 101.593 117.973 88.100  1.00 59.34  ? 59  TYR B OH  1 
ATOM 2210 N N   . ALA B 2 70  ? 99.336  110.585 83.951  1.00 45.57  ? 60  ALA B N   1 
ATOM 2211 C CA  . ALA B 2 70  ? 98.678  110.104 82.744  1.00 40.10  ? 60  ALA B CA  1 
ATOM 2212 C C   . ALA B 2 70  ? 98.539  108.590 82.798  1.00 48.62  ? 60  ALA B C   1 
ATOM 2213 O O   . ALA B 2 70  ? 99.322  107.902 83.458  1.00 46.53  ? 60  ALA B O   1 
ATOM 2214 C CB  . ALA B 2 70  ? 99.444  110.519 81.486  1.00 42.48  ? 60  ALA B CB  1 
ATOM 2215 N N   . MET B 2 71  ? 97.527  108.088 82.093  1.00 60.63  ? 61  MET B N   1 
ATOM 2216 C CA  . MET B 2 71  ? 97.336  106.660 81.885  1.00 53.21  ? 61  MET B CA  1 
ATOM 2217 C C   . MET B 2 71  ? 96.713  106.456 80.512  1.00 50.90  ? 61  MET B C   1 
ATOM 2218 O O   . MET B 2 71  ? 96.057  107.353 79.978  1.00 50.48  ? 61  MET B O   1 
ATOM 2219 C CB  . MET B 2 71  ? 96.465  106.025 82.978  1.00 41.29  ? 61  MET B CB  1 
ATOM 2220 C CG  . MET B 2 71  ? 95.127  106.712 83.223  1.00 45.05  ? 61  MET B CG  1 
ATOM 2221 S SD  . MET B 2 71  ? 93.841  106.260 82.039  1.00 59.77  ? 61  MET B SD  1 
ATOM 2222 C CE  . MET B 2 71  ? 93.955  104.472 82.066  1.00 53.34  ? 61  MET B CE  1 
ATOM 2223 N N   . HIS B 2 72  ? 96.929  105.273 79.937  1.00 39.84  ? 62  HIS B N   1 
ATOM 2224 C CA  . HIS B 2 72  ? 96.308  104.942 78.660  1.00 40.46  ? 62  HIS B CA  1 
ATOM 2225 C C   . HIS B 2 72  ? 96.064  103.444 78.571  1.00 44.38  ? 62  HIS B C   1 
ATOM 2226 O O   . HIS B 2 72  ? 96.971  102.644 78.819  1.00 43.40  ? 62  HIS B O   1 
ATOM 2227 C CB  . HIS B 2 72  ? 97.177  105.402 77.484  1.00 39.06  ? 62  HIS B CB  1 
ATOM 2228 C CG  . HIS B 2 72  ? 96.427  105.524 76.193  1.00 40.56  ? 62  HIS B CG  1 
ATOM 2229 N ND1 . HIS B 2 72  ? 97.050  105.768 74.989  1.00 36.82  ? 62  HIS B ND1 1 
ATOM 2230 C CD2 . HIS B 2 72  ? 95.104  105.431 75.919  1.00 45.17  ? 62  HIS B CD2 1 
ATOM 2231 C CE1 . HIS B 2 72  ? 96.144  105.822 74.028  1.00 39.32  ? 62  HIS B CE1 1 
ATOM 2232 N NE2 . HIS B 2 72  ? 94.955  105.621 74.567  1.00 41.34  ? 62  HIS B NE2 1 
ATOM 2233 N N   . TRP B 2 73  ? 94.833  103.079 78.218  1.00 45.29  ? 63  TRP B N   1 
ATOM 2234 C CA  . TRP B 2 73  ? 94.472  101.685 78.006  1.00 36.63  ? 63  TRP B CA  1 
ATOM 2235 C C   . TRP B 2 73  ? 95.100  101.140 76.728  1.00 29.65  ? 63  TRP B C   1 
ATOM 2236 O O   . TRP B 2 73  ? 95.254  101.849 75.730  1.00 36.09  ? 63  TRP B O   1 
ATOM 2237 C CB  . TRP B 2 73  ? 92.952  101.535 77.930  1.00 39.89  ? 63  TRP B CB  1 
ATOM 2238 C CG  . TRP B 2 73  ? 92.249  101.736 79.234  1.00 36.80  ? 63  TRP B CG  1 
ATOM 2239 C CD1 . TRP B 2 73  ? 91.663  102.883 79.680  1.00 31.55  ? 63  TRP B CD1 1 
ATOM 2240 C CD2 . TRP B 2 73  ? 92.038  100.754 80.255  1.00 30.25  ? 63  TRP B CD2 1 
ATOM 2241 N NE1 . TRP B 2 73  ? 91.109  102.682 80.920  1.00 34.90  ? 63  TRP B NE1 1 
ATOM 2242 C CE2 . TRP B 2 73  ? 91.324  101.382 81.296  1.00 35.76  ? 63  TRP B CE2 1 
ATOM 2243 C CE3 . TRP B 2 73  ? 92.387  99.407  80.393  1.00 36.04  ? 63  TRP B CE3 1 
ATOM 2244 C CZ2 . TRP B 2 73  ? 90.952  100.710 82.457  1.00 42.60  ? 63  TRP B CZ2 1 
ATOM 2245 C CZ3 . TRP B 2 73  ? 92.016  98.740  81.546  1.00 34.45  ? 63  TRP B CZ3 1 
ATOM 2246 C CH2 . TRP B 2 73  ? 91.307  99.393  82.564  1.00 31.37  ? 63  TRP B CH2 1 
ATOM 2247 N N   . GLY B 2 74  ? 95.467  99.858  76.769  1.00 42.10  ? 64  GLY B N   1 
ATOM 2248 C CA  . GLY B 2 74  ? 95.748  99.121  75.557  1.00 46.84  ? 64  GLY B CA  1 
ATOM 2249 C C   . GLY B 2 74  ? 94.484  98.702  74.826  1.00 51.07  ? 64  GLY B C   1 
ATOM 2250 O O   . GLY B 2 74  ? 93.376  98.738  75.361  1.00 57.44  ? 64  GLY B O   1 
ATOM 2251 N N   . THR B 2 75  ? 94.664  98.299  73.566  1.00 44.20  ? 65  THR B N   1 
ATOM 2252 C CA  . THR B 2 75  ? 93.527  97.971  72.714  1.00 41.75  ? 65  THR B CA  1 
ATOM 2253 C C   . THR B 2 75  ? 92.867  96.651  73.088  1.00 43.33  ? 65  THR B C   1 
ATOM 2254 O O   . THR B 2 75  ? 91.753  96.384  72.626  1.00 54.75  ? 65  THR B O   1 
ATOM 2255 C CB  . THR B 2 75  ? 93.953  97.927  71.246  1.00 45.75  ? 65  THR B CB  1 
ATOM 2256 O OG1 . THR B 2 75  ? 95.315  97.492  71.151  1.00 47.78  ? 65  THR B OG1 1 
ATOM 2257 C CG2 . THR B 2 75  ? 93.808  99.301  70.611  1.00 47.13  ? 65  THR B CG2 1 
ATOM 2258 N N   . ASP B 2 76  ? 93.521  95.823  73.900  1.00 46.11  ? 66  ASP B N   1 
ATOM 2259 C CA  . ASP B 2 76  ? 92.932  94.573  74.362  1.00 51.91  ? 66  ASP B CA  1 
ATOM 2260 C C   . ASP B 2 76  ? 91.980  94.764  75.534  1.00 47.66  ? 66  ASP B C   1 
ATOM 2261 O O   . ASP B 2 76  ? 91.405  93.778  76.008  1.00 48.68  ? 66  ASP B O   1 
ATOM 2262 C CB  . ASP B 2 76  ? 94.039  93.592  74.754  1.00 56.77  ? 66  ASP B CB  1 
ATOM 2263 C CG  . ASP B 2 76  ? 95.049  94.207  75.703  1.00 57.00  ? 66  ASP B CG  1 
ATOM 2264 O OD1 . ASP B 2 76  ? 95.299  95.426  75.595  1.00 50.26  ? 66  ASP B OD1 1 
ATOM 2265 O OD2 . ASP B 2 76  ? 95.592  93.477  76.556  1.00 58.09  ? 66  ASP B OD2 1 
ATOM 2266 N N   . SER B 2 77  ? 91.818  95.996  76.017  1.00 50.42  ? 67  SER B N   1 
ATOM 2267 C CA  . SER B 2 77  ? 90.913  96.343  77.112  1.00 55.94  ? 67  SER B CA  1 
ATOM 2268 C C   . SER B 2 77  ? 91.294  95.656  78.418  1.00 52.79  ? 67  SER B C   1 
ATOM 2269 O O   . SER B 2 77  ? 90.489  95.601  79.353  1.00 47.65  ? 67  SER B O   1 
ATOM 2270 C CB  . SER B 2 77  ? 89.455  96.032  76.756  1.00 60.09  ? 67  SER B CB  1 
ATOM 2271 O OG  . SER B 2 77  ? 89.023  96.812  75.654  1.00 60.22  ? 67  SER B OG  1 
ATOM 2272 N N   . ARG B 2 78  ? 92.509  95.129  78.499  1.00 50.14  ? 68  ARG B N   1 
ATOM 2273 C CA  . ARG B 2 78  ? 93.009  94.462  79.692  1.00 49.82  ? 68  ARG B CA  1 
ATOM 2274 C C   . ARG B 2 78  ? 94.304  95.068  80.201  1.00 35.87  ? 68  ARG B C   1 
ATOM 2275 O O   . ARG B 2 78  ? 94.476  95.223  81.413  1.00 49.62  ? 68  ARG B O   1 
ATOM 2276 C CB  . ARG B 2 78  ? 93.209  92.964  79.424  1.00 51.59  ? 68  ARG B CB  1 
ATOM 2277 C CG  . ARG B 2 78  ? 93.749  92.198  80.616  1.00 45.69  ? 68  ARG B CG  1 
ATOM 2278 C CD  . ARG B 2 78  ? 93.760  90.705  80.358  1.00 41.34  ? 68  ARG B CD  1 
ATOM 2279 N NE  . ARG B 2 78  ? 94.300  89.964  81.491  1.00 45.33  ? 68  ARG B NE  1 
ATOM 2280 C CZ  . ARG B 2 78  ? 94.230  88.647  81.627  1.00 53.21  ? 68  ARG B CZ  1 
ATOM 2281 N NH1 . ARG B 2 78  ? 93.632  87.889  80.723  1.00 51.49  ? 68  ARG B NH1 1 
ATOM 2282 N NH2 . ARG B 2 78  ? 94.767  88.077  82.702  1.00 55.19  ? 68  ARG B NH2 1 
ATOM 2283 N N   . LEU B 2 79  ? 95.220  95.417  79.305  1.00 19.15  ? 69  LEU B N   1 
ATOM 2284 C CA  . LEU B 2 79  ? 96.475  96.049  79.675  1.00 26.49  ? 69  LEU B CA  1 
ATOM 2285 C C   . LEU B 2 79  ? 96.343  97.559  79.564  1.00 38.20  ? 69  LEU B C   1 
ATOM 2286 O O   . LEU B 2 79  ? 95.685  98.072  78.654  1.00 52.82  ? 69  LEU B O   1 
ATOM 2287 C CB  . LEU B 2 79  ? 97.619  95.566  78.785  1.00 38.70  ? 69  LEU B CB  1 
ATOM 2288 C CG  . LEU B 2 79  ? 98.001  94.094  78.913  1.00 33.45  ? 69  LEU B CG  1 
ATOM 2289 C CD1 . LEU B 2 79  ? 99.196  93.771  78.031  1.00 23.54  ? 69  LEU B CD1 1 
ATOM 2290 C CD2 . LEU B 2 79  ? 98.289  93.748  80.363  1.00 24.81  ? 69  LEU B CD2 1 
ATOM 2291 N N   . LEU B 2 80  ? 96.978  98.266  80.493  1.00 47.93  ? 70  LEU B N   1 
ATOM 2292 C CA  . LEU B 2 80  ? 97.036  99.717  80.459  1.00 54.76  ? 70  LEU B CA  1 
ATOM 2293 C C   . LEU B 2 80  ? 98.414  100.171 80.913  1.00 49.68  ? 70  LEU B C   1 
ATOM 2294 O O   . LEU B 2 80  ? 99.094  99.479  81.674  1.00 42.09  ? 70  LEU B O   1 
ATOM 2295 C CB  . LEU B 2 80  ? 95.942  100.343 81.339  1.00 39.39  ? 70  LEU B CB  1 
ATOM 2296 C CG  . LEU B 2 80  ? 96.096  100.208 82.857  1.00 30.88  ? 70  LEU B CG  1 
ATOM 2297 C CD1 . LEU B 2 80  ? 96.690  101.466 83.475  1.00 44.01  ? 70  LEU B CD1 1 
ATOM 2298 C CD2 . LEU B 2 80  ? 94.764  99.869  83.500  1.00 32.88  ? 70  LEU B CD2 1 
ATOM 2299 N N   . VAL B 2 81  ? 98.816  101.344 80.435  1.00 39.84  ? 71  VAL B N   1 
ATOM 2300 C CA  . VAL B 2 81  ? 100.081 101.965 80.804  1.00 29.98  ? 71  VAL B CA  1 
ATOM 2301 C C   . VAL B 2 81  ? 99.775  103.275 81.516  1.00 42.94  ? 71  VAL B C   1 
ATOM 2302 O O   . VAL B 2 81  ? 98.915  104.044 81.073  1.00 47.65  ? 71  VAL B O   1 
ATOM 2303 C CB  . VAL B 2 81  ? 100.983 102.195 79.572  1.00 38.11  ? 71  VAL B CB  1 
ATOM 2304 C CG1 . VAL B 2 81  ? 100.232 102.952 78.487  1.00 38.05  ? 71  VAL B CG1 1 
ATOM 2305 C CG2 . VAL B 2 81  ? 102.248 102.933 79.965  1.00 37.86  ? 71  VAL B CG2 1 
ATOM 2306 N N   . SER B 2 82  ? 100.466 103.520 82.628  1.00 44.38  ? 72  SER B N   1 
ATOM 2307 C CA  . SER B 2 82  ? 100.311 104.759 83.377  1.00 38.43  ? 72  SER B CA  1 
ATOM 2308 C C   . SER B 2 82  ? 101.671 105.403 83.600  1.00 38.71  ? 72  SER B C   1 
ATOM 2309 O O   . SER B 2 82  ? 102.684 104.716 83.752  1.00 41.12  ? 72  SER B O   1 
ATOM 2310 C CB  . SER B 2 82  ? 99.627  104.517 84.726  1.00 39.86  ? 72  SER B CB  1 
ATOM 2311 O OG  . SER B 2 82  ? 100.397 103.650 85.541  1.00 40.27  ? 72  SER B OG  1 
ATOM 2312 N N   . ALA B 2 83  ? 101.683 106.733 83.623  1.00 36.12  ? 73  ALA B N   1 
ATOM 2313 C CA  . ALA B 2 83  ? 102.900 107.502 83.838  1.00 34.40  ? 73  ALA B CA  1 
ATOM 2314 C C   . ALA B 2 83  ? 102.777 108.318 85.116  1.00 34.11  ? 73  ALA B C   1 
ATOM 2315 O O   . ALA B 2 83  ? 101.747 108.957 85.353  1.00 38.40  ? 73  ALA B O   1 
ATOM 2316 C CB  . ALA B 2 83  ? 103.180 108.426 82.651  1.00 44.64  ? 73  ALA B CB  1 
ATOM 2317 N N   . SER B 2 84  ? 103.826 108.290 85.934  1.00 38.42  ? 74  SER B N   1 
ATOM 2318 C CA  . SER B 2 84  ? 103.892 109.062 87.166  1.00 35.80  ? 74  SER B CA  1 
ATOM 2319 C C   . SER B 2 84  ? 105.237 109.771 87.238  1.00 30.00  ? 74  SER B C   1 
ATOM 2320 O O   . SER B 2 84  ? 106.203 109.382 86.578  1.00 37.10  ? 74  SER B O   1 
ATOM 2321 C CB  . SER B 2 84  ? 103.688 108.186 88.408  1.00 45.21  ? 74  SER B CB  1 
ATOM 2322 O OG  . SER B 2 84  ? 103.826 108.949 89.595  1.00 47.21  ? 74  SER B OG  1 
ATOM 2323 N N   . GLN B 2 85  ? 105.294 110.816 88.062  1.00 43.29  ? 75  GLN B N   1 
ATOM 2324 C CA  . GLN B 2 85  ? 106.510 111.595 88.242  1.00 52.67  ? 75  GLN B CA  1 
ATOM 2325 C C   . GLN B 2 85  ? 107.426 111.026 89.322  1.00 56.11  ? 75  GLN B C   1 
ATOM 2326 O O   . GLN B 2 85  ? 108.262 111.759 89.861  1.00 52.79  ? 75  GLN B O   1 
ATOM 2327 C CB  . GLN B 2 85  ? 106.160 113.050 88.554  1.00 47.71  ? 75  GLN B CB  1 
ATOM 2328 C CG  . GLN B 2 85  ? 105.424 113.749 87.428  1.00 40.93  ? 75  GLN B CG  1 
ATOM 2329 C CD  . GLN B 2 85  ? 105.156 115.208 87.723  1.00 50.47  ? 75  GLN B CD  1 
ATOM 2330 O OE1 . GLN B 2 85  ? 105.296 115.659 88.860  1.00 55.86  ? 75  GLN B OE1 1 
ATOM 2331 N NE2 . GLN B 2 85  ? 104.771 115.959 86.697  1.00 53.42  ? 75  GLN B NE2 1 
ATOM 2332 N N   . ASP B 2 86  ? 107.288 109.742 89.645  1.00 50.36  ? 76  ASP B N   1 
ATOM 2333 C CA  . ASP B 2 86  ? 108.338 108.990 90.317  1.00 47.66  ? 76  ASP B CA  1 
ATOM 2334 C C   . ASP B 2 86  ? 109.355 108.417 89.338  1.00 53.30  ? 76  ASP B C   1 
ATOM 2335 O O   . ASP B 2 86  ? 110.202 107.612 89.739  1.00 57.56  ? 76  ASP B O   1 
ATOM 2336 C CB  . ASP B 2 86  ? 107.728 107.865 91.156  1.00 47.19  ? 76  ASP B CB  1 
ATOM 2337 C CG  . ASP B 2 86  ? 107.017 106.825 90.311  1.00 53.71  ? 76  ASP B CG  1 
ATOM 2338 O OD1 . ASP B 2 86  ? 106.611 107.154 89.176  1.00 57.20  ? 76  ASP B OD1 1 
ATOM 2339 O OD2 . ASP B 2 86  ? 106.864 105.679 90.782  1.00 49.10  ? 76  ASP B OD2 1 
ATOM 2340 N N   . GLY B 2 87  ? 109.286 108.816 88.071  1.00 45.73  ? 77  GLY B N   1 
ATOM 2341 C CA  . GLY B 2 87  ? 110.190 108.313 87.055  1.00 36.18  ? 77  GLY B CA  1 
ATOM 2342 C C   . GLY B 2 87  ? 109.932 106.885 86.631  1.00 44.97  ? 77  GLY B C   1 
ATOM 2343 O O   . GLY B 2 87  ? 110.863 106.197 86.203  1.00 47.77  ? 77  GLY B O   1 
ATOM 2344 N N   . LYS B 2 88  ? 108.689 106.417 86.732  1.00 53.11  ? 78  LYS B N   1 
ATOM 2345 C CA  . LYS B 2 88  ? 108.351 105.037 86.410  1.00 40.69  ? 78  LYS B CA  1 
ATOM 2346 C C   . LYS B 2 88  ? 107.167 105.002 85.456  1.00 35.63  ? 78  LYS B C   1 
ATOM 2347 O O   . LYS B 2 88  ? 106.116 105.584 85.743  1.00 41.59  ? 78  LYS B O   1 
ATOM 2348 C CB  . LYS B 2 88  ? 108.028 104.239 87.678  1.00 37.04  ? 78  LYS B CB  1 
ATOM 2349 C CG  . LYS B 2 88  ? 109.241 103.911 88.529  1.00 42.53  ? 78  LYS B CG  1 
ATOM 2350 C CD  . LYS B 2 88  ? 110.166 102.952 87.804  1.00 45.40  ? 78  LYS B CD  1 
ATOM 2351 C CE  . LYS B 2 88  ? 111.302 102.496 88.701  1.00 53.55  ? 78  LYS B CE  1 
ATOM 2352 N NZ  . LYS B 2 88  ? 112.175 101.497 88.025  1.00 53.73  ? 78  LYS B NZ  1 
ATOM 2353 N N   . LEU B 2 89  ? 107.339 104.317 84.330  1.00 39.06  ? 79  LEU B N   1 
ATOM 2354 C CA  . LEU B 2 89  ? 106.233 103.913 83.473  1.00 39.29  ? 79  LEU B CA  1 
ATOM 2355 C C   . LEU B 2 89  ? 105.870 102.474 83.824  1.00 39.02  ? 79  LEU B C   1 
ATOM 2356 O O   . LEU B 2 89  ? 106.724 101.584 83.753  1.00 53.39  ? 79  LEU B O   1 
ATOM 2357 C CB  . LEU B 2 89  ? 106.617 104.043 82.000  1.00 45.41  ? 79  LEU B CB  1 
ATOM 2358 C CG  . LEU B 2 89  ? 105.489 104.146 80.976  1.00 41.02  ? 79  LEU B CG  1 
ATOM 2359 C CD1 . LEU B 2 89  ? 104.647 105.377 81.245  1.00 43.44  ? 79  LEU B CD1 1 
ATOM 2360 C CD2 . LEU B 2 89  ? 106.054 104.186 79.566  1.00 47.76  ? 79  LEU B CD2 1 
ATOM 2361 N N   . ILE B 2 90  ? 104.613 102.244 84.197  1.00 30.87  ? 80  ILE B N   1 
ATOM 2362 C CA  . ILE B 2 90  ? 104.145 100.925 84.610  1.00 34.39  ? 80  ILE B CA  1 
ATOM 2363 C C   . ILE B 2 90  ? 103.034 100.470 83.675  1.00 44.74  ? 80  ILE B C   1 
ATOM 2364 O O   . ILE B 2 90  ? 102.120 101.243 83.365  1.00 46.57  ? 80  ILE B O   1 
ATOM 2365 C CB  . ILE B 2 90  ? 103.654 100.930 86.070  1.00 36.87  ? 80  ILE B CB  1 
ATOM 2366 C CG1 . ILE B 2 90  ? 104.752 101.440 87.006  1.00 47.75  ? 80  ILE B CG1 1 
ATOM 2367 C CG2 . ILE B 2 90  ? 103.217 99.538  86.488  1.00 30.60  ? 80  ILE B CG2 1 
ATOM 2368 C CD1 . ILE B 2 90  ? 104.397 101.345 88.473  1.00 40.60  ? 80  ILE B CD1 1 
ATOM 2369 N N   . ILE B 2 91  ? 103.116 99.217  83.232  1.00 48.06  ? 81  ILE B N   1 
ATOM 2370 C CA  . ILE B 2 91  ? 102.067 98.568  82.452  1.00 42.70  ? 81  ILE B CA  1 
ATOM 2371 C C   . ILE B 2 91  ? 101.363 97.578  83.369  1.00 42.18  ? 81  ILE B C   1 
ATOM 2372 O O   . ILE B 2 91  ? 102.008 96.701  83.956  1.00 45.69  ? 81  ILE B O   1 
ATOM 2373 C CB  . ILE B 2 91  ? 102.629 97.872  81.204  1.00 30.43  ? 81  ILE B CB  1 
ATOM 2374 C CG1 . ILE B 2 91  ? 103.397 98.875  80.343  1.00 39.14  ? 81  ILE B CG1 1 
ATOM 2375 C CG2 . ILE B 2 91  ? 101.506 97.237  80.402  1.00 37.06  ? 81  ILE B CG2 1 
ATOM 2376 C CD1 . ILE B 2 91  ? 104.011 98.273  79.105  1.00 41.87  ? 81  ILE B CD1 1 
ATOM 2377 N N   . TRP B 2 92  ? 100.045 97.713  83.495  1.00 42.63  ? 82  TRP B N   1 
ATOM 2378 C CA  . TRP B 2 92  ? 99.268  96.935  84.449  1.00 42.83  ? 82  TRP B CA  1 
ATOM 2379 C C   . TRP B 2 92  ? 98.420  95.892  83.733  1.00 47.41  ? 82  TRP B C   1 
ATOM 2380 O O   . TRP B 2 92  ? 97.849  96.162  82.672  1.00 60.26  ? 82  TRP B O   1 
ATOM 2381 C CB  . TRP B 2 92  ? 98.345  97.838  85.273  1.00 51.68  ? 82  TRP B CB  1 
ATOM 2382 C CG  . TRP B 2 92  ? 99.031  98.963  85.975  1.00 54.63  ? 82  TRP B CG  1 
ATOM 2383 C CD1 . TRP B 2 92  ? 99.367  100.174 85.445  1.00 53.39  ? 82  TRP B CD1 1 
ATOM 2384 C CD2 . TRP B 2 92  ? 99.438  98.998  87.347  1.00 44.86  ? 82  TRP B CD2 1 
ATOM 2385 N NE1 . TRP B 2 92  ? 99.973  100.956 86.397  1.00 49.95  ? 82  TRP B NE1 1 
ATOM 2386 C CE2 . TRP B 2 92  ? 100.027 100.258 87.574  1.00 49.12  ? 82  TRP B CE2 1 
ATOM 2387 C CE3 . TRP B 2 92  ? 99.368  98.084  88.402  1.00 34.73  ? 82  TRP B CE3 1 
ATOM 2388 C CZ2 . TRP B 2 92  ? 100.544 100.626 88.810  1.00 54.73  ? 82  TRP B CZ2 1 
ATOM 2389 C CZ3 . TRP B 2 92  ? 99.881  98.451  89.628  1.00 35.89  ? 82  TRP B CZ3 1 
ATOM 2390 C CH2 . TRP B 2 92  ? 100.460 99.713  89.823  1.00 45.79  ? 82  TRP B CH2 1 
ATOM 2391 N N   . ASP B 2 93  ? 98.344  94.701  84.324  1.00 40.07  ? 83  ASP B N   1 
ATOM 2392 C CA  . ASP B 2 93  ? 97.327  93.711  83.974  1.00 44.38  ? 83  ASP B CA  1 
ATOM 2393 C C   . ASP B 2 93  ? 96.131  93.968  84.882  1.00 51.52  ? 83  ASP B C   1 
ATOM 2394 O O   . ASP B 2 93  ? 96.143  93.603  86.059  1.00 54.61  ? 83  ASP B O   1 
ATOM 2395 C CB  . ASP B 2 93  ? 97.870  92.295  84.130  1.00 44.10  ? 83  ASP B CB  1 
ATOM 2396 C CG  . ASP B 2 93  ? 96.928  91.243  83.576  1.00 52.89  ? 83  ASP B CG  1 
ATOM 2397 O OD1 . ASP B 2 93  ? 95.882  91.616  83.006  1.00 66.26  ? 83  ASP B OD1 1 
ATOM 2398 O OD2 . ASP B 2 93  ? 97.232  90.040  83.712  1.00 50.50  ? 83  ASP B OD2 1 
ATOM 2399 N N   . SER B 2 94  ? 95.088  94.596  84.335  1.00 49.13  ? 84  SER B N   1 
ATOM 2400 C CA  . SER B 2 94  ? 93.982  95.050  85.172  1.00 42.15  ? 84  SER B CA  1 
ATOM 2401 C C   . SER B 2 94  ? 93.176  93.894  85.753  1.00 61.13  ? 84  SER B C   1 
ATOM 2402 O O   . SER B 2 94  ? 92.564  94.045  86.816  1.00 73.68  ? 84  SER B O   1 
ATOM 2403 C CB  . SER B 2 94  ? 93.069  95.981  84.373  1.00 41.75  ? 84  SER B CB  1 
ATOM 2404 O OG  . SER B 2 94  ? 92.522  95.321  83.245  1.00 60.59  ? 84  SER B OG  1 
ATOM 2405 N N   . TYR B 2 95  ? 93.165  92.737  85.087  1.00 61.01  ? 85  TYR B N   1 
ATOM 2406 C CA  . TYR B 2 95  ? 92.392  91.606  85.597  1.00 60.19  ? 85  TYR B CA  1 
ATOM 2407 C C   . TYR B 2 95  ? 92.974  91.067  86.898  1.00 58.32  ? 85  TYR B C   1 
ATOM 2408 O O   . TYR B 2 95  ? 92.228  90.723  87.822  1.00 56.39  ? 85  TYR B O   1 
ATOM 2409 C CB  . TYR B 2 95  ? 92.315  90.497  84.548  1.00 57.03  ? 85  TYR B CB  1 
ATOM 2410 C CG  . TYR B 2 95  ? 91.391  90.797  83.387  1.00 59.71  ? 85  TYR B CG  1 
ATOM 2411 C CD1 . TYR B 2 95  ? 90.772  92.032  83.262  1.00 61.80  ? 85  TYR B CD1 1 
ATOM 2412 C CD2 . TYR B 2 95  ? 91.118  89.830  82.430  1.00 61.51  ? 85  TYR B CD2 1 
ATOM 2413 C CE1 . TYR B 2 95  ? 89.926  92.304  82.207  1.00 63.90  ? 85  TYR B CE1 1 
ATOM 2414 C CE2 . TYR B 2 95  ? 90.271  90.093  81.372  1.00 58.79  ? 85  TYR B CE2 1 
ATOM 2415 C CZ  . TYR B 2 95  ? 89.677  91.331  81.266  1.00 62.75  ? 85  TYR B CZ  1 
ATOM 2416 O OH  . TYR B 2 95  ? 88.831  91.597  80.215  1.00 62.73  ? 85  TYR B OH  1 
ATOM 2417 N N   . THR B 2 96  ? 94.300  90.984  86.990  1.00 41.64  ? 86  THR B N   1 
ATOM 2418 C CA  . THR B 2 96  ? 94.970  90.400  88.142  1.00 45.53  ? 86  THR B CA  1 
ATOM 2419 C C   . THR B 2 96  ? 95.698  91.424  89.001  1.00 47.73  ? 86  THR B C   1 
ATOM 2420 O O   . THR B 2 96  ? 96.247  91.049  90.042  1.00 53.17  ? 86  THR B O   1 
ATOM 2421 C CB  . THR B 2 96  ? 95.968  89.319  87.697  1.00 50.11  ? 86  THR B CB  1 
ATOM 2422 O OG1 . THR B 2 96  ? 96.952  89.896  86.830  1.00 50.74  ? 86  THR B OG1 1 
ATOM 2423 C CG2 . THR B 2 96  ? 95.248  88.200  86.964  1.00 52.23  ? 86  THR B CG2 1 
ATOM 2424 N N   . THR B 2 97  ? 95.737  92.687  88.580  1.00 39.33  ? 87  THR B N   1 
ATOM 2425 C CA  . THR B 2 97  ? 96.547  93.759  89.157  1.00 40.73  ? 87  THR B CA  1 
ATOM 2426 C C   . THR B 2 97  ? 98.038  93.473  89.066  1.00 50.68  ? 87  THR B C   1 
ATOM 2427 O O   . THR B 2 97  ? 98.838  94.166  89.706  1.00 52.49  ? 87  THR B O   1 
ATOM 2428 C CB  . THR B 2 97  ? 96.170  94.053  90.617  1.00 50.82  ? 87  THR B CB  1 
ATOM 2429 O OG1 . THR B 2 97  ? 96.533  92.940  91.444  1.00 57.93  ? 87  THR B OG1 1 
ATOM 2430 C CG2 . THR B 2 97  ? 94.679  94.304  90.742  1.00 50.58  ? 87  THR B CG2 1 
ATOM 2431 N N   . ASN B 2 98  ? 98.432  92.468  88.291  1.00 55.21  ? 88  ASN B N   1 
ATOM 2432 C CA  . ASN B 2 98  ? 99.845  92.211  88.066  1.00 49.19  ? 88  ASN B CA  1 
ATOM 2433 C C   . ASN B 2 98  ? 100.451 93.320  87.218  1.00 50.07  ? 88  ASN B C   1 
ATOM 2434 O O   . ASN B 2 98  ? 99.816  93.839  86.296  1.00 50.43  ? 88  ASN B O   1 
ATOM 2435 C CB  . ASN B 2 98  ? 100.041 90.857  87.384  1.00 45.82  ? 88  ASN B CB  1 
ATOM 2436 C CG  . ASN B 2 98  ? 99.697  89.691  88.290  1.00 48.89  ? 88  ASN B CG  1 
ATOM 2437 O OD1 . ASN B 2 98  ? 99.796  89.790  89.513  1.00 46.09  ? 88  ASN B OD1 1 
ATOM 2438 N ND2 . ASN B 2 98  ? 99.289  88.577  87.692  1.00 47.44  ? 88  ASN B ND2 1 
ATOM 2439 N N   . LYS B 2 99  ? 101.687 93.682  87.535  1.00 43.63  ? 89  LYS B N   1 
ATOM 2440 C CA  . LYS B 2 99  ? 102.464 94.596  86.711  1.00 43.79  ? 89  LYS B CA  1 
ATOM 2441 C C   . LYS B 2 99  ? 103.167 93.803  85.618  1.00 55.54  ? 89  LYS B C   1 
ATOM 2442 O O   . LYS B 2 99  ? 103.960 92.902  85.909  1.00 64.78  ? 89  LYS B O   1 
ATOM 2443 C CB  . LYS B 2 99  ? 103.462 95.382  87.558  1.00 32.44  ? 89  LYS B CB  1 
ATOM 2444 C CG  . LYS B 2 99  ? 102.806 96.194  88.655  1.00 42.77  ? 89  LYS B CG  1 
ATOM 2445 C CD  . LYS B 2 99  ? 103.824 97.009  89.422  1.00 42.83  ? 89  LYS B CD  1 
ATOM 2446 C CE  . LYS B 2 99  ? 103.167 97.735  90.573  1.00 50.28  ? 89  LYS B CE  1 
ATOM 2447 N NZ  . LYS B 2 99  ? 102.559 96.792  91.549  1.00 46.68  ? 89  LYS B NZ  1 
ATOM 2448 N N   . VAL B 2 100 ? 102.842 94.109  84.363  1.00 38.47  ? 90  VAL B N   1 
ATOM 2449 C CA  . VAL B 2 100 ? 103.444 93.394  83.244  1.00 26.56  ? 90  VAL B CA  1 
ATOM 2450 C C   . VAL B 2 100 ? 104.829 93.947  82.930  1.00 33.29  ? 90  VAL B C   1 
ATOM 2451 O O   . VAL B 2 100 ? 105.767 93.188  82.668  1.00 33.63  ? 90  VAL B O   1 
ATOM 2452 C CB  . VAL B 2 100 ? 102.512 93.461  82.022  1.00 35.11  ? 90  VAL B CB  1 
ATOM 2453 C CG1 . VAL B 2 100 ? 103.088 92.666  80.872  1.00 45.51  ? 90  VAL B CG1 1 
ATOM 2454 C CG2 . VAL B 2 100 ? 101.135 92.945  82.388  1.00 41.80  ? 90  VAL B CG2 1 
ATOM 2455 N N   . HIS B 2 101 ? 104.983 95.268  82.955  1.00 39.41  ? 91  HIS B N   1 
ATOM 2456 C CA  . HIS B 2 101 ? 106.267 95.903  82.703  1.00 41.79  ? 91  HIS B CA  1 
ATOM 2457 C C   . HIS B 2 101 ? 106.427 97.092  83.639  1.00 42.76  ? 91  HIS B C   1 
ATOM 2458 O O   . HIS B 2 101 ? 105.448 97.652  84.138  1.00 44.42  ? 91  HIS B O   1 
ATOM 2459 C CB  . HIS B 2 101 ? 106.404 96.365  81.244  1.00 33.76  ? 91  HIS B CB  1 
ATOM 2460 C CG  . HIS B 2 101 ? 106.303 95.258  80.241  1.00 32.08  ? 91  HIS B CG  1 
ATOM 2461 N ND1 . HIS B 2 101 ? 107.329 94.368  80.009  1.00 30.40  ? 91  HIS B ND1 1 
ATOM 2462 C CD2 . HIS B 2 101 ? 105.301 94.906  79.402  1.00 37.88  ? 91  HIS B CD2 1 
ATOM 2463 C CE1 . HIS B 2 101 ? 106.961 93.511  79.073  1.00 43.45  ? 91  HIS B CE1 1 
ATOM 2464 N NE2 . HIS B 2 101 ? 105.735 93.815  78.688  1.00 46.54  ? 91  HIS B NE2 1 
ATOM 2465 N N   . ALA B 2 102 ? 107.682 97.471  83.870  1.00 41.74  ? 92  ALA B N   1 
ATOM 2466 C CA  . ALA B 2 102 ? 108.012 98.706  84.575  1.00 31.15  ? 92  ALA B CA  1 
ATOM 2467 C C   . ALA B 2 102 ? 109.141 99.375  83.808  1.00 45.59  ? 92  ALA B C   1 
ATOM 2468 O O   . ALA B 2 102 ? 110.282 98.904  83.842  1.00 56.41  ? 92  ALA B O   1 
ATOM 2469 C CB  . ALA B 2 102 ? 108.416 98.440  86.024  1.00 31.10  ? 92  ALA B CB  1 
ATOM 2470 N N   . ILE B 2 103 ? 108.825 100.470 83.124  1.00 36.80  ? 93  ILE B N   1 
ATOM 2471 C CA  . ILE B 2 103 ? 109.761 101.140 82.227  1.00 23.60  ? 93  ILE B CA  1 
ATOM 2472 C C   . ILE B 2 103 ? 110.347 102.339 82.965  1.00 29.66  ? 93  ILE B C   1 
ATOM 2473 O O   . ILE B 2 103 ? 109.606 103.292 83.260  1.00 44.22  ? 93  ILE B O   1 
ATOM 2474 C CB  . ILE B 2 103 ? 109.074 101.570 80.926  1.00 29.26  ? 93  ILE B CB  1 
ATOM 2475 C CG1 . ILE B 2 103 ? 108.209 100.430 80.384  1.00 35.96  ? 93  ILE B CG1 1 
ATOM 2476 C CG2 . ILE B 2 103 ? 110.105 101.989 79.902  1.00 40.19  ? 93  ILE B CG2 1 
ATOM 2477 C CD1 . ILE B 2 103 ? 107.401 100.801 79.169  1.00 38.57  ? 93  ILE B CD1 1 
ATOM 2478 N N   . PRO B 2 104 ? 111.642 102.346 83.279  1.00 41.67  ? 94  PRO B N   1 
ATOM 2479 C CA  . PRO B 2 104 ? 112.241 103.535 83.898  1.00 45.53  ? 94  PRO B CA  1 
ATOM 2480 C C   . PRO B 2 104 ? 112.422 104.637 82.865  1.00 42.90  ? 94  PRO B C   1 
ATOM 2481 O O   . PRO B 2 104 ? 113.016 104.424 81.806  1.00 40.56  ? 94  PRO B O   1 
ATOM 2482 C CB  . PRO B 2 104 ? 113.585 103.022 84.425  1.00 45.02  ? 94  PRO B CB  1 
ATOM 2483 C CG  . PRO B 2 104 ? 113.913 101.870 83.535  1.00 49.50  ? 94  PRO B CG  1 
ATOM 2484 C CD  . PRO B 2 104 ? 112.601 101.234 83.165  1.00 43.25  ? 94  PRO B CD  1 
ATOM 2485 N N   . LEU B 2 105 ? 111.906 105.821 83.181  1.00 45.78  ? 95  LEU B N   1 
ATOM 2486 C CA  . LEU B 2 105 ? 111.966 106.952 82.268  1.00 44.03  ? 95  LEU B CA  1 
ATOM 2487 C C   . LEU B 2 105 ? 113.250 107.738 82.491  1.00 48.38  ? 95  LEU B C   1 
ATOM 2488 O O   . LEU B 2 105 ? 113.676 107.945 83.631  1.00 49.15  ? 95  LEU B O   1 
ATOM 2489 C CB  . LEU B 2 105 ? 110.751 107.862 82.457  1.00 42.00  ? 95  LEU B CB  1 
ATOM 2490 C CG  . LEU B 2 105 ? 109.387 107.184 82.311  1.00 40.82  ? 95  LEU B CG  1 
ATOM 2491 C CD1 . LEU B 2 105 ? 108.265 108.202 82.400  1.00 45.34  ? 95  LEU B CD1 1 
ATOM 2492 C CD2 . LEU B 2 105 ? 109.309 106.408 81.006  1.00 37.76  ? 95  LEU B CD2 1 
ATOM 2493 N N   . ARG B 2 106 ? 113.865 108.171 81.389  1.00 59.87  ? 96  ARG B N   1 
ATOM 2494 C CA  . ARG B 2 106 ? 115.072 108.985 81.484  1.00 61.55  ? 96  ARG B CA  1 
ATOM 2495 C C   . ARG B 2 106 ? 114.785 110.325 82.150  1.00 56.15  ? 96  ARG B C   1 
ATOM 2496 O O   . ARG B 2 106 ? 115.592 110.815 82.949  1.00 53.49  ? 96  ARG B O   1 
ATOM 2497 C CB  . ARG B 2 106 ? 115.681 109.176 80.095  1.00 59.21  ? 96  ARG B CB  1 
ATOM 2498 C CG  . ARG B 2 106 ? 116.382 107.928 79.578  1.00 59.39  ? 96  ARG B CG  1 
ATOM 2499 C CD  . ARG B 2 106 ? 116.485 107.914 78.064  1.00 63.27  ? 96  ARG B CD  1 
ATOM 2500 N NE  . ARG B 2 106 ? 117.224 106.749 77.593  1.00 65.11  ? 96  ARG B NE  1 
ATOM 2501 C CZ  . ARG B 2 106 ? 117.246 106.335 76.334  1.00 62.84  ? 96  ARG B CZ  1 
ATOM 2502 N NH1 . ARG B 2 106 ? 116.562 106.957 75.389  1.00 60.18  ? 96  ARG B NH1 1 
ATOM 2503 N NH2 . ARG B 2 106 ? 117.968 105.264 76.016  1.00 62.48  ? 96  ARG B NH2 1 
ATOM 2504 N N   . SER B 2 107 ? 113.645 110.932 81.836  1.00 57.33  ? 97  SER B N   1 
ATOM 2505 C CA  . SER B 2 107 ? 113.204 112.159 82.483  1.00 59.71  ? 97  SER B CA  1 
ATOM 2506 C C   . SER B 2 107 ? 111.963 111.852 83.308  1.00 58.12  ? 97  SER B C   1 
ATOM 2507 O O   . SER B 2 107 ? 110.978 111.324 82.782  1.00 60.77  ? 97  SER B O   1 
ATOM 2508 C CB  . SER B 2 107 ? 112.907 113.251 81.453  1.00 64.28  ? 97  SER B CB  1 
ATOM 2509 O OG  . SER B 2 107 ? 112.442 114.433 82.082  1.00 60.10  ? 97  SER B OG  1 
ATOM 2510 N N   . SER B 2 108 ? 112.014 112.186 84.598  1.00 53.83  ? 98  SER B N   1 
ATOM 2511 C CA  . SER B 2 108 ? 110.930 111.848 85.510  1.00 52.40  ? 98  SER B CA  1 
ATOM 2512 C C   . SER B 2 108 ? 109.759 112.817 85.440  1.00 49.23  ? 98  SER B C   1 
ATOM 2513 O O   . SER B 2 108 ? 108.719 112.547 86.050  1.00 51.37  ? 98  SER B O   1 
ATOM 2514 C CB  . SER B 2 108 ? 111.458 111.788 86.946  1.00 53.61  ? 98  SER B CB  1 
ATOM 2515 O OG  . SER B 2 108 ? 112.045 113.020 87.327  1.00 58.11  ? 98  SER B OG  1 
ATOM 2516 N N   . TRP B 2 109 ? 109.893 113.928 84.723  1.00 56.59  ? 99  TRP B N   1 
ATOM 2517 C CA  . TRP B 2 109 ? 108.841 114.942 84.682  1.00 60.43  ? 99  TRP B CA  1 
ATOM 2518 C C   . TRP B 2 109 ? 107.849 114.664 83.560  1.00 58.42  ? 99  TRP B C   1 
ATOM 2519 O O   . TRP B 2 109 ? 107.540 115.525 82.738  1.00 63.30  ? 99  TRP B O   1 
ATOM 2520 C CB  . TRP B 2 109 ? 109.457 116.328 84.549  1.00 60.92  ? 99  TRP B CB  1 
ATOM 2521 C CG  . TRP B 2 109 ? 110.463 116.601 85.611  1.00 59.31  ? 99  TRP B CG  1 
ATOM 2522 C CD1 . TRP B 2 109 ? 111.806 116.770 85.447  1.00 60.41  ? 99  TRP B CD1 1 
ATOM 2523 C CD2 . TRP B 2 109 ? 110.215 116.695 87.017  1.00 50.06  ? 99  TRP B CD2 1 
ATOM 2524 N NE1 . TRP B 2 109 ? 112.408 116.986 86.663  1.00 57.12  ? 99  TRP B NE1 1 
ATOM 2525 C CE2 . TRP B 2 109 ? 111.451 116.942 87.643  1.00 54.21  ? 99  TRP B CE2 1 
ATOM 2526 C CE3 . TRP B 2 109 ? 109.066 116.603 87.807  1.00 53.61  ? 99  TRP B CE3 1 
ATOM 2527 C CZ2 . TRP B 2 109 ? 111.571 117.099 89.021  1.00 63.80  ? 99  TRP B CZ2 1 
ATOM 2528 C CZ3 . TRP B 2 109 ? 109.188 116.758 89.173  1.00 58.24  ? 99  TRP B CZ3 1 
ATOM 2529 C CH2 . TRP B 2 109 ? 110.429 117.004 89.767  1.00 62.91  ? 99  TRP B CH2 1 
ATOM 2530 N N   . VAL B 2 110 ? 107.340 113.440 83.533  1.00 37.49  ? 100 VAL B N   1 
ATOM 2531 C CA  . VAL B 2 110 ? 106.465 112.992 82.459  1.00 32.61  ? 100 VAL B CA  1 
ATOM 2532 C C   . VAL B 2 110 ? 105.074 113.571 82.673  1.00 34.29  ? 100 VAL B C   1 
ATOM 2533 O O   . VAL B 2 110 ? 104.594 113.687 83.808  1.00 45.04  ? 100 VAL B O   1 
ATOM 2534 C CB  . VAL B 2 110 ? 106.441 111.454 82.391  1.00 24.03  ? 100 VAL B CB  1 
ATOM 2535 C CG1 . VAL B 2 110 ? 105.935 110.865 83.699  1.00 31.65  ? 100 VAL B CG1 1 
ATOM 2536 C CG2 . VAL B 2 110 ? 105.609 110.975 81.213  1.00 31.79  ? 100 VAL B CG2 1 
ATOM 2537 N N   . MET B 2 111 ? 104.427 113.962 81.577  1.00 43.18  ? 101 MET B N   1 
ATOM 2538 C CA  . MET B 2 111 ? 103.088 114.525 81.625  1.00 48.98  ? 101 MET B CA  1 
ATOM 2539 C C   . MET B 2 111 ? 102.067 113.731 80.830  1.00 53.04  ? 101 MET B C   1 
ATOM 2540 O O   . MET B 2 111 ? 100.866 113.904 81.061  1.00 50.39  ? 101 MET B O   1 
ATOM 2541 C CB  . MET B 2 111 ? 103.091 115.974 81.113  1.00 53.71  ? 101 MET B CB  1 
ATOM 2542 C CG  . MET B 2 111 ? 103.911 116.929 81.963  1.00 51.95  ? 101 MET B CG  1 
ATOM 2543 S SD  . MET B 2 111 ? 103.810 118.632 81.385  1.00 58.25  ? 101 MET B SD  1 
ATOM 2544 C CE  . MET B 2 111 ? 102.052 118.934 81.534  1.00 54.55  ? 101 MET B CE  1 
ATOM 2545 N N   . THR B 2 112 ? 102.500 112.879 79.904  1.00 44.37  ? 102 THR B N   1 
ATOM 2546 C CA  . THR B 2 112 ? 101.587 112.116 79.071  1.00 41.49  ? 102 THR B CA  1 
ATOM 2547 C C   . THR B 2 112 ? 102.181 110.742 78.799  1.00 50.46  ? 102 THR B C   1 
ATOM 2548 O O   . THR B 2 112 ? 103.394 110.536 78.881  1.00 57.15  ? 102 THR B O   1 
ATOM 2549 C CB  . THR B 2 112 ? 101.286 112.829 77.750  1.00 47.18  ? 102 THR B CB  1 
ATOM 2550 O OG1 . THR B 2 112 ? 100.345 112.056 76.995  1.00 53.02  ? 102 THR B OG1 1 
ATOM 2551 C CG2 . THR B 2 112 ? 102.559 113.003 76.939  1.00 48.55  ? 102 THR B CG2 1 
ATOM 2552 N N   . CYS B 2 113 ? 101.301 109.799 78.471  1.00 41.54  ? 103 CYS B N   1 
ATOM 2553 C CA  . CYS B 2 113 ? 101.710 108.470 78.046  1.00 43.91  ? 103 CYS B CA  1 
ATOM 2554 C C   . CYS B 2 113 ? 100.669 107.933 77.076  1.00 49.74  ? 103 CYS B C   1 
ATOM 2555 O O   . CYS B 2 113 ? 99.488  108.283 77.156  1.00 54.72  ? 103 CYS B O   1 
ATOM 2556 C CB  . CYS B 2 113 ? 101.889 107.521 79.236  1.00 41.77  ? 103 CYS B CB  1 
ATOM 2557 S SG  . CYS B 2 113 ? 100.376 107.176 80.146  1.00 45.51  ? 103 CYS B SG  1 
ATOM 2558 N N   . ALA B 2 114 ? 101.117 107.084 76.155  1.00 49.55  ? 104 ALA B N   1 
ATOM 2559 C CA  . ALA B 2 114 ? 100.236 106.506 75.152  1.00 44.56  ? 104 ALA B CA  1 
ATOM 2560 C C   . ALA B 2 114 ? 100.555 105.034 74.946  1.00 42.46  ? 104 ALA B C   1 
ATOM 2561 O O   . ALA B 2 114 ? 101.717 104.627 75.001  1.00 43.82  ? 104 ALA B O   1 
ATOM 2562 C CB  . ALA B 2 114 ? 100.352 107.248 73.815  1.00 46.92  ? 104 ALA B CB  1 
ATOM 2563 N N   . TYR B 2 115 ? 99.509  104.245 74.720  1.00 40.04  ? 105 TYR B N   1 
ATOM 2564 C CA  . TYR B 2 115 ? 99.630  102.836 74.373  1.00 40.17  ? 105 TYR B CA  1 
ATOM 2565 C C   . TYR B 2 115 ? 99.337  102.668 72.887  1.00 43.46  ? 105 TYR B C   1 
ATOM 2566 O O   . TYR B 2 115 ? 98.294  103.121 72.403  1.00 46.17  ? 105 TYR B O   1 
ATOM 2567 C CB  . TYR B 2 115 ? 98.665  101.990 75.207  1.00 46.63  ? 105 TYR B CB  1 
ATOM 2568 C CG  . TYR B 2 115 ? 99.199  100.632 75.602  1.00 43.08  ? 105 TYR B CG  1 
ATOM 2569 C CD1 . TYR B 2 115 ? 100.037 99.918  74.760  1.00 49.58  ? 105 TYR B CD1 1 
ATOM 2570 C CD2 . TYR B 2 115 ? 98.868  100.067 76.824  1.00 32.30  ? 105 TYR B CD2 1 
ATOM 2571 C CE1 . TYR B 2 115 ? 100.525 98.678  75.122  1.00 43.93  ? 105 TYR B CE1 1 
ATOM 2572 C CE2 . TYR B 2 115 ? 99.352  98.827  77.193  1.00 25.15  ? 105 TYR B CE2 1 
ATOM 2573 C CZ  . TYR B 2 115 ? 100.180 98.139  76.339  1.00 33.87  ? 105 TYR B CZ  1 
ATOM 2574 O OH  . TYR B 2 115 ? 100.665 96.905  76.704  1.00 50.63  ? 105 TYR B OH  1 
ATOM 2575 N N   . ALA B 2 116 ? 100.256 102.029 72.168  1.00 40.65  ? 106 ALA B N   1 
ATOM 2576 C CA  . ALA B 2 116 ? 100.057 101.818 70.742  1.00 41.83  ? 106 ALA B CA  1 
ATOM 2577 C C   . ALA B 2 116 ? 98.882  100.872 70.510  1.00 48.48  ? 106 ALA B C   1 
ATOM 2578 O O   . ALA B 2 116 ? 98.679  99.931  71.285  1.00 50.60  ? 106 ALA B O   1 
ATOM 2579 C CB  . ALA B 2 116 ? 101.320 101.251 70.095  1.00 45.81  ? 106 ALA B CB  1 
ATOM 2580 N N   . PRO B 2 117 ? 98.084  101.098 69.462  1.00 56.47  ? 107 PRO B N   1 
ATOM 2581 C CA  . PRO B 2 117 ? 96.961  100.186 69.191  1.00 54.15  ? 107 PRO B CA  1 
ATOM 2582 C C   . PRO B 2 117 ? 97.394  98.759  68.917  1.00 54.34  ? 107 PRO B C   1 
ATOM 2583 O O   . PRO B 2 117 ? 96.631  97.825  69.195  1.00 52.43  ? 107 PRO B O   1 
ATOM 2584 C CB  . PRO B 2 117 ? 96.286  100.819 67.966  1.00 53.60  ? 107 PRO B CB  1 
ATOM 2585 C CG  . PRO B 2 117 ? 97.357  101.633 67.321  1.00 54.63  ? 107 PRO B CG  1 
ATOM 2586 C CD  . PRO B 2 117 ? 98.196  102.158 68.446  1.00 55.97  ? 107 PRO B CD  1 
ATOM 2587 N N   . SER B 2 118 ? 98.599  98.557  68.381  1.00 60.66  ? 108 SER B N   1 
ATOM 2588 C CA  . SER B 2 118 ? 99.109  97.205  68.203  1.00 55.85  ? 108 SER B CA  1 
ATOM 2589 C C   . SER B 2 118 ? 99.533  96.580  69.524  1.00 54.59  ? 108 SER B C   1 
ATOM 2590 O O   . SER B 2 118 ? 99.585  95.350  69.626  1.00 62.29  ? 108 SER B O   1 
ATOM 2591 C CB  . SER B 2 118 ? 100.284 97.206  67.225  1.00 53.55  ? 108 SER B CB  1 
ATOM 2592 O OG  . SER B 2 118 ? 101.355 97.995  67.713  1.00 56.73  ? 108 SER B OG  1 
ATOM 2593 N N   . GLY B 2 119 ? 99.833  97.397  70.531  1.00 50.29  ? 109 GLY B N   1 
ATOM 2594 C CA  . GLY B 2 119 ? 100.310 96.911  71.805  1.00 47.58  ? 109 GLY B CA  1 
ATOM 2595 C C   . GLY B 2 119 ? 101.804 96.698  71.879  1.00 52.03  ? 109 GLY B C   1 
ATOM 2596 O O   . GLY B 2 119 ? 102.301 96.265  72.927  1.00 49.13  ? 109 GLY B O   1 
ATOM 2597 N N   . ASN B 2 120 ? 102.534 96.989  70.805  1.00 53.46  ? 110 ASN B N   1 
ATOM 2598 C CA  . ASN B 2 120 ? 103.970 96.766  70.745  1.00 57.11  ? 110 ASN B CA  1 
ATOM 2599 C C   . ASN B 2 120 ? 104.785 97.961  71.220  1.00 60.90  ? 110 ASN B C   1 
ATOM 2600 O O   . ASN B 2 120 ? 105.986 97.810  71.469  1.00 63.21  ? 110 ASN B O   1 
ATOM 2601 C CB  . ASN B 2 120 ? 104.391 96.415  69.313  1.00 59.83  ? 110 ASN B CB  1 
ATOM 2602 C CG  . ASN B 2 120 ? 103.597 95.259  68.737  1.00 62.20  ? 110 ASN B CG  1 
ATOM 2603 O OD1 . ASN B 2 120 ? 103.104 94.401  69.468  1.00 63.75  ? 110 ASN B OD1 1 
ATOM 2604 N ND2 . ASN B 2 120 ? 103.473 95.229  67.414  1.00 61.54  ? 110 ASN B ND2 1 
ATOM 2605 N N   . TYR B 2 121 ? 104.175 99.138  71.348  1.00 59.01  ? 111 TYR B N   1 
ATOM 2606 C CA  . TYR B 2 121 ? 104.914 100.349 71.669  1.00 55.36  ? 111 TYR B CA  1 
ATOM 2607 C C   . TYR B 2 121 ? 104.150 101.184 72.684  1.00 54.78  ? 111 TYR B C   1 
ATOM 2608 O O   . TYR B 2 121 ? 102.921 101.131 72.761  1.00 55.52  ? 111 TYR B O   1 
ATOM 2609 C CB  . TYR B 2 121 ? 105.184 101.195 70.416  1.00 55.61  ? 111 TYR B CB  1 
ATOM 2610 C CG  . TYR B 2 121 ? 106.000 100.492 69.357  1.00 57.85  ? 111 TYR B CG  1 
ATOM 2611 C CD1 . TYR B 2 121 ? 107.387 100.498 69.405  1.00 59.62  ? 111 TYR B CD1 1 
ATOM 2612 C CD2 . TYR B 2 121 ? 105.384 99.828  68.306  1.00 60.20  ? 111 TYR B CD2 1 
ATOM 2613 C CE1 . TYR B 2 121 ? 108.138 99.858  68.437  1.00 58.25  ? 111 TYR B CE1 1 
ATOM 2614 C CE2 . TYR B 2 121 ? 106.127 99.186  67.333  1.00 59.17  ? 111 TYR B CE2 1 
ATOM 2615 C CZ  . TYR B 2 121 ? 107.502 99.204  67.404  1.00 57.83  ? 111 TYR B CZ  1 
ATOM 2616 O OH  . TYR B 2 121 ? 108.243 98.565  66.437  1.00 60.01  ? 111 TYR B OH  1 
ATOM 2617 N N   . VAL B 2 122 ? 104.903 101.944 73.480  1.00 47.85  ? 112 VAL B N   1 
ATOM 2618 C CA  . VAL B 2 122 ? 104.356 103.004 74.314  1.00 46.75  ? 112 VAL B CA  1 
ATOM 2619 C C   . VAL B 2 122 ? 105.183 104.267 74.114  1.00 53.58  ? 112 VAL B C   1 
ATOM 2620 O O   . VAL B 2 122 ? 106.352 104.222 73.724  1.00 61.41  ? 112 VAL B O   1 
ATOM 2621 C CB  . VAL B 2 122 ? 104.310 102.619 75.809  1.00 49.33  ? 112 VAL B CB  1 
ATOM 2622 C CG1 . VAL B 2 122 ? 103.291 101.516 76.042  1.00 42.78  ? 112 VAL B CG1 1 
ATOM 2623 C CG2 . VAL B 2 122 ? 105.682 102.188 76.286  1.00 56.74  ? 112 VAL B CG2 1 
ATOM 2624 N N   . ALA B 2 123 ? 104.552 105.408 74.384  1.00 52.08  ? 113 ALA B N   1 
ATOM 2625 C CA  . ALA B 2 123 ? 105.170 106.714 74.215  1.00 54.85  ? 113 ALA B CA  1 
ATOM 2626 C C   . ALA B 2 123 ? 104.916 107.548 75.459  1.00 61.17  ? 113 ALA B C   1 
ATOM 2627 O O   . ALA B 2 123 ? 103.922 107.352 76.162  1.00 53.07  ? 113 ALA B O   1 
ATOM 2628 C CB  . ALA B 2 123 ? 104.636 107.452 72.984  1.00 50.94  ? 113 ALA B CB  1 
ATOM 2629 N N   . CYS B 2 124 ? 105.828 108.477 75.729  1.00 78.30  ? 114 CYS B N   1 
ATOM 2630 C CA  . CYS B 2 124 ? 105.685 109.377 76.864  1.00 67.59  ? 114 CYS B CA  1 
ATOM 2631 C C   . CYS B 2 124 ? 106.542 110.610 76.621  1.00 63.22  ? 114 CYS B C   1 
ATOM 2632 O O   . CYS B 2 124 ? 107.408 110.628 75.744  1.00 69.14  ? 114 CYS B O   1 
ATOM 2633 C CB  . CYS B 2 124 ? 106.077 108.690 78.175  1.00 62.18  ? 114 CYS B CB  1 
ATOM 2634 S SG  . CYS B 2 124 ? 107.795 108.136 78.229  1.00 74.40  ? 114 CYS B SG  1 
ATOM 2635 N N   . GLY B 2 125 ? 106.287 111.644 77.418  1.00 54.15  ? 115 GLY B N   1 
ATOM 2636 C CA  . GLY B 2 125 ? 107.070 112.860 77.356  1.00 58.18  ? 115 GLY B CA  1 
ATOM 2637 C C   . GLY B 2 125 ? 106.512 113.963 78.229  1.00 64.09  ? 115 GLY B C   1 
ATOM 2638 O O   . GLY B 2 125 ? 105.310 113.999 78.508  1.00 71.48  ? 115 GLY B O   1 
ATOM 2639 N N   . GLY B 2 126 ? 107.379 114.871 78.666  1.00 64.26  ? 116 GLY B N   1 
ATOM 2640 C CA  . GLY B 2 126 ? 106.964 115.954 79.534  1.00 67.88  ? 116 GLY B CA  1 
ATOM 2641 C C   . GLY B 2 126 ? 107.744 117.235 79.324  1.00 67.75  ? 116 GLY B C   1 
ATOM 2642 O O   . GLY B 2 126 ? 107.885 117.715 78.196  1.00 67.88  ? 116 GLY B O   1 
ATOM 2643 N N   . LEU B 2 127 ? 108.259 117.794 80.421  1.00 63.51  ? 117 LEU B N   1 
ATOM 2644 C CA  . LEU B 2 127 ? 109.042 119.022 80.381  1.00 64.11  ? 117 LEU B CA  1 
ATOM 2645 C C   . LEU B 2 127 ? 110.373 118.860 79.658  1.00 69.65  ? 117 LEU B C   1 
ATOM 2646 O O   . LEU B 2 127 ? 111.041 119.868 79.401  1.00 74.25  ? 117 LEU B O   1 
ATOM 2647 C CB  . LEU B 2 127 ? 109.294 119.524 81.804  1.00 64.01  ? 117 LEU B CB  1 
ATOM 2648 C CG  . LEU B 2 127 ? 108.072 119.647 82.718  1.00 65.51  ? 117 LEU B CG  1 
ATOM 2649 C CD1 . LEU B 2 127 ? 108.473 120.193 84.080  1.00 65.96  ? 117 LEU B CD1 1 
ATOM 2650 C CD2 . LEU B 2 127 ? 107.015 120.522 82.079  1.00 68.24  ? 117 LEU B CD2 1 
ATOM 2651 N N   . ASP B 2 128 ? 110.776 117.635 79.326  1.00 65.86  ? 118 ASP B N   1 
ATOM 2652 C CA  . ASP B 2 128 ? 112.016 117.409 78.595  1.00 65.98  ? 118 ASP B CA  1 
ATOM 2653 C C   . ASP B 2 128 ? 111.883 117.626 77.094  1.00 67.61  ? 118 ASP B C   1 
ATOM 2654 O O   . ASP B 2 128 ? 112.884 117.490 76.381  1.00 65.94  ? 118 ASP B O   1 
ATOM 2655 C CB  . ASP B 2 128 ? 112.526 115.991 78.864  1.00 64.71  ? 118 ASP B CB  1 
ATOM 2656 C CG  . ASP B 2 128 ? 111.456 114.938 78.656  1.00 71.61  ? 118 ASP B CG  1 
ATOM 2657 O OD1 . ASP B 2 128 ? 110.284 115.206 78.995  1.00 74.51  ? 118 ASP B OD1 1 
ATOM 2658 O OD2 . ASP B 2 128 ? 111.785 113.843 78.154  1.00 73.29  ? 118 ASP B OD2 1 
ATOM 2659 N N   . ASN B 2 129 ? 110.686 117.944 76.600  1.00 68.56  ? 119 ASN B N   1 
ATOM 2660 C CA  . ASN B 2 129 ? 110.444 118.267 75.193  1.00 70.23  ? 119 ASN B CA  1 
ATOM 2661 C C   . ASN B 2 129 ? 110.728 117.091 74.262  1.00 71.39  ? 119 ASN B C   1 
ATOM 2662 O O   . ASN B 2 129 ? 110.985 117.292 73.071  1.00 73.31  ? 119 ASN B O   1 
ATOM 2663 C CB  . ASN B 2 129 ? 111.256 119.492 74.752  1.00 65.80  ? 119 ASN B CB  1 
ATOM 2664 C CG  . ASN B 2 129 ? 110.951 120.724 75.581  1.00 63.70  ? 119 ASN B CG  1 
ATOM 2665 O OD1 . ASN B 2 129 ? 110.387 120.630 76.671  1.00 66.53  ? 119 ASN B OD1 1 
ATOM 2666 N ND2 . ASN B 2 129 ? 111.319 121.891 75.063  1.00 62.10  ? 119 ASN B ND2 1 
ATOM 2667 N N   . ILE B 2 130 ? 110.686 115.862 74.773  1.00 58.61  ? 120 ILE B N   1 
ATOM 2668 C CA  . ILE B 2 130 ? 111.062 114.677 74.011  1.00 51.84  ? 120 ILE B CA  1 
ATOM 2669 C C   . ILE B 2 130 ? 109.921 113.672 74.076  1.00 59.75  ? 120 ILE B C   1 
ATOM 2670 O O   . ILE B 2 130 ? 109.315 113.474 75.135  1.00 65.88  ? 120 ILE B O   1 
ATOM 2671 C CB  . ILE B 2 130 ? 112.367 114.050 74.547  1.00 57.26  ? 120 ILE B CB  1 
ATOM 2672 C CG1 . ILE B 2 130 ? 113.525 115.044 74.434  1.00 61.44  ? 120 ILE B CG1 1 
ATOM 2673 C CG2 . ILE B 2 130 ? 112.700 112.770 73.798  1.00 63.07  ? 120 ILE B CG2 1 
ATOM 2674 C CD1 . ILE B 2 130 ? 113.808 115.493 73.020  1.00 59.50  ? 120 ILE B CD1 1 
ATOM 2675 N N   . CYS B 2 131 ? 109.630 113.035 72.942  1.00 68.66  ? 121 CYS B N   1 
ATOM 2676 C CA  . CYS B 2 131 ? 108.723 111.892 72.883  1.00 63.37  ? 121 CYS B CA  1 
ATOM 2677 C C   . CYS B 2 131 ? 109.551 110.622 72.729  1.00 63.12  ? 121 CYS B C   1 
ATOM 2678 O O   . CYS B 2 131 ? 110.165 110.398 71.681  1.00 69.06  ? 121 CYS B O   1 
ATOM 2679 C CB  . CYS B 2 131 ? 107.732 112.037 71.730  1.00 60.33  ? 121 CYS B CB  1 
ATOM 2680 S SG  . CYS B 2 131 ? 106.541 110.683 71.606  1.00 77.08  ? 121 CYS B SG  1 
ATOM 2681 N N   . SER B 2 132 ? 109.567 109.793 73.768  1.00 50.73  ? 122 SER B N   1 
ATOM 2682 C CA  . SER B 2 132 ? 110.351 108.566 73.775  1.00 56.97  ? 122 SER B CA  1 
ATOM 2683 C C   . SER B 2 132 ? 109.451 107.393 73.415  1.00 59.99  ? 122 SER B C   1 
ATOM 2684 O O   . SER B 2 132 ? 108.371 107.234 73.995  1.00 58.38  ? 122 SER B O   1 
ATOM 2685 C CB  . SER B 2 132 ? 110.997 108.339 75.142  1.00 65.31  ? 122 SER B CB  1 
ATOM 2686 O OG  . SER B 2 132 ? 111.864 109.407 75.482  1.00 63.06  ? 122 SER B OG  1 
ATOM 2687 N N   . ILE B 2 133 ? 109.896 106.574 72.464  1.00 62.21  ? 123 ILE B N   1 
ATOM 2688 C CA  . ILE B 2 133 ? 109.157 105.394 72.030  1.00 58.96  ? 123 ILE B CA  1 
ATOM 2689 C C   . ILE B 2 133 ? 109.822 104.161 72.622  1.00 57.73  ? 123 ILE B C   1 
ATOM 2690 O O   . ILE B 2 133 ? 111.041 103.985 72.506  1.00 57.63  ? 123 ILE B O   1 
ATOM 2691 C CB  . ILE B 2 133 ? 109.097 105.303 70.496  1.00 56.40  ? 123 ILE B CB  1 
ATOM 2692 C CG1 . ILE B 2 133 ? 108.595 106.620 69.901  1.00 60.07  ? 123 ILE B CG1 1 
ATOM 2693 C CG2 . ILE B 2 133 ? 108.194 104.158 70.070  1.00 57.80  ? 123 ILE B CG2 1 
ATOM 2694 C CD1 . ILE B 2 133 ? 107.185 106.979 70.317  1.00 60.22  ? 123 ILE B CD1 1 
ATOM 2695 N N   . TYR B 2 134 ? 109.022 103.306 73.253  1.00 51.71  ? 124 TYR B N   1 
ATOM 2696 C CA  . TYR B 2 134 ? 109.509 102.101 73.909  1.00 45.29  ? 124 TYR B CA  1 
ATOM 2697 C C   . TYR B 2 134 ? 108.929 100.882 73.207  1.00 53.03  ? 124 TYR B C   1 
ATOM 2698 O O   . TYR B 2 134 ? 107.718 100.817 72.974  1.00 56.03  ? 124 TYR B O   1 
ATOM 2699 C CB  . TYR B 2 134 ? 109.128 102.092 75.389  1.00 39.00  ? 124 TYR B CB  1 
ATOM 2700 C CG  . TYR B 2 134 ? 109.798 103.170 76.208  1.00 46.11  ? 124 TYR B CG  1 
ATOM 2701 C CD1 . TYR B 2 134 ? 111.086 103.000 76.693  1.00 53.80  ? 124 TYR B CD1 1 
ATOM 2702 C CD2 . TYR B 2 134 ? 109.139 104.355 76.501  1.00 45.57  ? 124 TYR B CD2 1 
ATOM 2703 C CE1 . TYR B 2 134 ? 111.700 103.982 77.445  1.00 50.06  ? 124 TYR B CE1 1 
ATOM 2704 C CE2 . TYR B 2 134 ? 109.746 105.342 77.251  1.00 49.44  ? 124 TYR B CE2 1 
ATOM 2705 C CZ  . TYR B 2 134 ? 111.027 105.150 77.721  1.00 53.14  ? 124 TYR B CZ  1 
ATOM 2706 O OH  . TYR B 2 134 ? 111.638 106.130 78.468  1.00 55.50  ? 124 TYR B OH  1 
ATOM 2707 N N   . ASN B 2 135 ? 109.787 99.920  72.880  1.00 58.06  ? 125 ASN B N   1 
ATOM 2708 C CA  . ASN B 2 135 ? 109.361 98.690  72.224  1.00 57.87  ? 125 ASN B CA  1 
ATOM 2709 C C   . ASN B 2 135 ? 108.995 97.653  73.280  1.00 61.65  ? 125 ASN B C   1 
ATOM 2710 O O   . ASN B 2 135 ? 109.835 97.279  74.107  1.00 68.35  ? 125 ASN B O   1 
ATOM 2711 C CB  . ASN B 2 135 ? 110.456 98.159  71.300  1.00 55.33  ? 125 ASN B CB  1 
ATOM 2712 C CG  . ASN B 2 135 ? 109.949 97.088  70.352  1.00 56.21  ? 125 ASN B CG  1 
ATOM 2713 O OD1 . ASN B 2 135 ? 108.743 96.887  70.214  1.00 66.31  ? 125 ASN B OD1 1 
ATOM 2714 N ND2 . ASN B 2 135 ? 110.870 96.402  69.686  1.00 56.59  ? 125 ASN B ND2 1 
ATOM 2715 N N   . LEU B 2 136 ? 107.744 97.193  73.251  1.00 54.81  ? 126 LEU B N   1 
ATOM 2716 C CA  . LEU B 2 136 ? 107.259 96.229  74.230  1.00 57.40  ? 126 LEU B CA  1 
ATOM 2717 C C   . LEU B 2 136 ? 107.462 94.780  73.808  1.00 53.31  ? 126 LEU B C   1 
ATOM 2718 O O   . LEU B 2 136 ? 107.445 93.893  74.669  1.00 52.12  ? 126 LEU B O   1 
ATOM 2719 C CB  . LEU B 2 136 ? 105.772 96.463  74.508  1.00 53.68  ? 126 LEU B CB  1 
ATOM 2720 C CG  . LEU B 2 136 ? 105.403 97.856  75.013  1.00 53.13  ? 126 LEU B CG  1 
ATOM 2721 C CD1 . LEU B 2 136 ? 103.928 97.915  75.355  1.00 53.14  ? 126 LEU B CD1 1 
ATOM 2722 C CD2 . LEU B 2 136 ? 106.245 98.223  76.219  1.00 53.61  ? 126 LEU B CD2 1 
ATOM 2723 N N   . LYS B 2 137 ? 107.652 94.516  72.519  1.00 49.49  ? 127 LYS B N   1 
ATOM 2724 C CA  . LYS B 2 137 ? 107.767 93.156  71.995  1.00 49.19  ? 127 LYS B CA  1 
ATOM 2725 C C   . LYS B 2 137 ? 109.165 93.004  71.406  1.00 56.26  ? 127 LYS B C   1 
ATOM 2726 O O   . LYS B 2 137 ? 109.376 93.222  70.210  1.00 62.85  ? 127 LYS B O   1 
ATOM 2727 C CB  . LYS B 2 137 ? 106.686 92.863  70.960  1.00 51.47  ? 127 LYS B CB  1 
ATOM 2728 C CG  . LYS B 2 137 ? 105.273 93.116  71.448  1.00 57.82  ? 127 LYS B CG  1 
ATOM 2729 C CD  . LYS B 2 137 ? 104.944 92.249  72.649  1.00 55.96  ? 127 LYS B CD  1 
ATOM 2730 C CE  . LYS B 2 137 ? 103.509 92.461  73.097  1.00 59.29  ? 127 LYS B CE  1 
ATOM 2731 N NZ  . LYS B 2 137 ? 102.548 92.115  72.014  1.00 48.26  ? 127 LYS B NZ  1 
ATOM 2732 N N   . THR B 2 138 ? 110.118 92.628  72.252  1.00 68.71  ? 128 THR B N   1 
ATOM 2733 C CA  . THR B 2 138 ? 111.487 92.380  71.832  1.00 74.22  ? 128 THR B CA  1 
ATOM 2734 C C   . THR B 2 138 ? 111.862 90.937  72.134  1.00 73.59  ? 128 THR B C   1 
ATOM 2735 O O   . THR B 2 138 ? 111.343 90.326  73.074  1.00 76.47  ? 128 THR B O   1 
ATOM 2736 C CB  . THR B 2 138 ? 112.473 93.323  72.538  1.00 72.96  ? 128 THR B CB  1 
ATOM 2737 O OG1 . THR B 2 138 ? 112.490 93.035  73.942  1.00 73.34  ? 128 THR B OG1 1 
ATOM 2738 C CG2 . THR B 2 138 ? 112.069 94.772  72.332  1.00 71.68  ? 128 THR B CG2 1 
ATOM 2739 N N   . ARG B 2 139 ? 112.773 90.395  71.324  1.00 75.52  ? 129 ARG B N   1 
ATOM 2740 C CA  . ARG B 2 139 ? 113.285 89.055  71.578  1.00 73.59  ? 129 ARG B CA  1 
ATOM 2741 C C   . ARG B 2 139 ? 114.104 88.991  72.858  1.00 75.54  ? 129 ARG B C   1 
ATOM 2742 O O   . ARG B 2 139 ? 114.309 87.897  73.394  1.00 78.87  ? 129 ARG B O   1 
ATOM 2743 C CB  . ARG B 2 139 ? 114.122 88.569  70.393  1.00 70.69  ? 129 ARG B CB  1 
ATOM 2744 C CG  . ARG B 2 139 ? 113.325 88.365  69.113  1.00 76.74  ? 129 ARG B CG  1 
ATOM 2745 C CD  . ARG B 2 139 ? 114.100 87.532  68.103  1.00 79.09  ? 129 ARG B CD  1 
ATOM 2746 N NE  . ARG B 2 139 ? 114.391 86.194  68.603  1.00 81.49  ? 129 ARG B NE  1 
ATOM 2747 C CZ  . ARG B 2 139 ? 115.009 85.251  67.904  1.00 81.32  ? 129 ARG B CZ  1 
ATOM 2748 N NH1 . ARG B 2 139 ? 115.417 85.465  66.664  1.00 77.39  ? 129 ARG B NH1 1 
ATOM 2749 N NH2 . ARG B 2 139 ? 115.223 84.064  68.464  1.00 78.91  ? 129 ARG B NH2 1 
ATOM 2750 N N   . GLU B 2 140 ? 114.575 90.134  73.358  1.00 71.95  ? 130 GLU B N   1 
ATOM 2751 C CA  . GLU B 2 140 ? 115.369 90.160  74.578  1.00 73.72  ? 130 GLU B CA  1 
ATOM 2752 C C   . GLU B 2 140 ? 114.517 90.102  75.838  1.00 77.19  ? 130 GLU B C   1 
ATOM 2753 O O   . GLU B 2 140 ? 115.064 89.881  76.924  1.00 79.85  ? 130 GLU B O   1 
ATOM 2754 C CB  . GLU B 2 140 ? 116.232 91.426  74.620  1.00 75.37  ? 130 GLU B CB  1 
ATOM 2755 C CG  . GLU B 2 140 ? 117.353 91.478  73.592  1.00 81.35  ? 130 GLU B CG  1 
ATOM 2756 C CD  . GLU B 2 140 ? 116.851 91.743  72.185  1.00 84.44  ? 130 GLU B CD  1 
ATOM 2757 O OE1 . GLU B 2 140 ? 115.684 92.160  72.038  1.00 82.98  ? 130 GLU B OE1 1 
ATOM 2758 O OE2 . GLU B 2 140 ? 117.624 91.532  71.227  1.00 82.55  ? 130 GLU B OE2 1 
ATOM 2759 N N   . GLY B 2 141 ? 113.205 90.292  75.724  1.00 66.62  ? 131 GLY B N   1 
ATOM 2760 C CA  . GLY B 2 141 ? 112.321 90.166  76.861  1.00 63.64  ? 131 GLY B CA  1 
ATOM 2761 C C   . GLY B 2 141 ? 112.211 91.397  77.729  1.00 61.95  ? 131 GLY B C   1 
ATOM 2762 O O   . GLY B 2 141 ? 111.557 91.339  78.776  1.00 68.38  ? 131 GLY B O   1 
ATOM 2763 N N   . ASN B 2 142 ? 112.827 92.507  77.332  1.00 65.91  ? 132 ASN B N   1 
ATOM 2764 C CA  . ASN B 2 142 ? 112.766 93.748  78.087  1.00 63.80  ? 132 ASN B CA  1 
ATOM 2765 C C   . ASN B 2 142 ? 112.300 94.874  77.177  1.00 67.32  ? 132 ASN B C   1 
ATOM 2766 O O   . ASN B 2 142 ? 112.418 94.802  75.951  1.00 76.57  ? 132 ASN B O   1 
ATOM 2767 C CB  . ASN B 2 142 ? 114.123 94.100  78.715  1.00 66.23  ? 132 ASN B CB  1 
ATOM 2768 C CG  . ASN B 2 142 ? 115.262 94.058  77.712  1.00 75.98  ? 132 ASN B CG  1 
ATOM 2769 O OD1 . ASN B 2 142 ? 115.049 93.858  76.517  1.00 79.98  ? 132 ASN B OD1 1 
ATOM 2770 N ND2 . ASN B 2 142 ? 116.483 94.248  78.199  1.00 75.52  ? 132 ASN B ND2 1 
ATOM 2771 N N   . VAL B 2 143 ? 111.764 95.919  77.795  1.00 49.80  ? 133 VAL B N   1 
ATOM 2772 C CA  . VAL B 2 143 ? 111.364 97.115  77.065  1.00 46.25  ? 133 VAL B CA  1 
ATOM 2773 C C   . VAL B 2 143 ? 112.580 98.006  76.854  1.00 52.10  ? 133 VAL B C   1 
ATOM 2774 O O   . VAL B 2 143 ? 113.310 98.319  77.803  1.00 56.97  ? 133 VAL B O   1 
ATOM 2775 C CB  . VAL B 2 143 ? 110.253 97.860  77.817  1.00 40.98  ? 133 VAL B CB  1 
ATOM 2776 C CG1 . VAL B 2 143 ? 109.755 99.021  76.991  1.00 48.01  ? 133 VAL B CG1 1 
ATOM 2777 C CG2 . VAL B 2 143 ? 109.117 96.911  78.152  1.00 41.74  ? 133 VAL B CG2 1 
ATOM 2778 N N   . ARG B 2 144 ? 112.801 98.419  75.608  1.00 53.37  ? 134 ARG B N   1 
ATOM 2779 C CA  . ARG B 2 144 ? 113.913 99.288  75.260  1.00 58.66  ? 134 ARG B CA  1 
ATOM 2780 C C   . ARG B 2 144 ? 113.393 100.504 74.508  1.00 54.93  ? 134 ARG B C   1 
ATOM 2781 O O   . ARG B 2 144 ? 112.353 100.448 73.847  1.00 52.35  ? 134 ARG B O   1 
ATOM 2782 C CB  . ARG B 2 144 ? 114.957 98.555  74.409  1.00 64.70  ? 134 ARG B CB  1 
ATOM 2783 C CG  . ARG B 2 144 ? 114.416 98.023  73.093  1.00 58.55  ? 134 ARG B CG  1 
ATOM 2784 C CD  . ARG B 2 144 ? 115.493 97.289  72.316  1.00 60.82  ? 134 ARG B CD  1 
ATOM 2785 N NE  . ARG B 2 144 ? 114.999 96.791  71.038  1.00 62.20  ? 134 ARG B NE  1 
ATOM 2786 C CZ  . ARG B 2 144 ? 115.726 96.097  70.175  1.00 66.35  ? 134 ARG B CZ  1 
ATOM 2787 N NH1 . ARG B 2 144 ? 116.991 95.796  70.422  1.00 70.68  ? 134 ARG B NH1 1 
ATOM 2788 N NH2 . ARG B 2 144 ? 115.172 95.694  69.036  1.00 64.57  ? 134 ARG B NH2 1 
ATOM 2789 N N   . VAL B 2 145 ? 114.132 101.607 74.618  1.00 58.26  ? 135 VAL B N   1 
ATOM 2790 C CA  . VAL B 2 145 ? 113.834 102.805 73.840  1.00 61.13  ? 135 VAL B CA  1 
ATOM 2791 C C   . VAL B 2 145 ? 114.135 102.537 72.371  1.00 61.82  ? 135 VAL B C   1 
ATOM 2792 O O   . VAL B 2 145 ? 115.253 102.148 72.013  1.00 64.20  ? 135 VAL B O   1 
ATOM 2793 C CB  . VAL B 2 145 ? 114.634 104.007 74.357  1.00 61.45  ? 135 VAL B CB  1 
ATOM 2794 C CG1 . VAL B 2 145 ? 113.972 105.311 73.927  1.00 59.52  ? 135 VAL B CG1 1 
ATOM 2795 C CG2 . VAL B 2 145 ? 114.784 103.936 75.867  1.00 64.13  ? 135 VAL B CG2 1 
ATOM 2796 N N   . SER B 2 146 ? 113.138 102.743 71.513  1.00 60.78  ? 136 SER B N   1 
ATOM 2797 C CA  . SER B 2 146 ? 113.326 102.610 70.074  1.00 57.65  ? 136 SER B CA  1 
ATOM 2798 C C   . SER B 2 146 ? 113.499 103.942 69.360  1.00 63.48  ? 136 SER B C   1 
ATOM 2799 O O   . SER B 2 146 ? 114.210 104.001 68.351  1.00 70.58  ? 136 SER B O   1 
ATOM 2800 C CB  . SER B 2 146 ? 112.146 101.858 69.449  1.00 61.28  ? 136 SER B CB  1 
ATOM 2801 O OG  . SER B 2 146 ? 110.929 102.544 69.677  1.00 59.67  ? 136 SER B OG  1 
ATOM 2802 N N   . ARG B 2 147 ? 112.881 105.012 69.859  1.00 69.90  ? 137 ARG B N   1 
ATOM 2803 C CA  . ARG B 2 147 ? 112.970 106.322 69.229  1.00 70.03  ? 137 ARG B CA  1 
ATOM 2804 C C   . ARG B 2 147 ? 112.794 107.414 70.274  1.00 75.28  ? 137 ARG B C   1 
ATOM 2805 O O   . ARG B 2 147 ? 112.029 107.262 71.230  1.00 79.82  ? 137 ARG B O   1 
ATOM 2806 C CB  . ARG B 2 147 ? 111.922 106.490 68.122  1.00 71.09  ? 137 ARG B CB  1 
ATOM 2807 C CG  . ARG B 2 147 ? 112.369 106.006 66.754  1.00 72.15  ? 137 ARG B CG  1 
ATOM 2808 C CD  . ARG B 2 147 ? 113.488 106.879 66.207  1.00 71.65  ? 137 ARG B CD  1 
ATOM 2809 N NE  . ARG B 2 147 ? 113.878 106.497 64.855  1.00 77.15  ? 137 ARG B NE  1 
ATOM 2810 C CZ  . ARG B 2 147 ? 114.857 105.650 64.569  1.00 77.60  ? 137 ARG B CZ  1 
ATOM 2811 N NH1 . ARG B 2 147 ? 115.573 105.074 65.521  1.00 75.01  ? 137 ARG B NH1 1 
ATOM 2812 N NH2 . ARG B 2 147 ? 115.129 105.377 63.296  1.00 74.65  ? 137 ARG B NH2 1 
ATOM 2813 N N   . GLU B 2 148 ? 113.512 108.518 70.075  1.00 71.13  ? 138 GLU B N   1 
ATOM 2814 C CA  . GLU B 2 148 ? 113.310 109.757 70.822  1.00 67.86  ? 138 GLU B CA  1 
ATOM 2815 C C   . GLU B 2 148 ? 112.972 110.855 69.822  1.00 68.24  ? 138 GLU B C   1 
ATOM 2816 O O   . GLU B 2 148 ? 113.826 111.254 69.023  1.00 67.04  ? 138 GLU B O   1 
ATOM 2817 C CB  . GLU B 2 148 ? 114.550 110.127 71.635  1.00 66.86  ? 138 GLU B CB  1 
ATOM 2818 C CG  . GLU B 2 148 ? 115.046 109.038 72.566  1.00 68.80  ? 138 GLU B CG  1 
ATOM 2819 C CD  . GLU B 2 148 ? 116.307 109.444 73.301  1.00 71.04  ? 138 GLU B CD  1 
ATOM 2820 O OE1 . GLU B 2 148 ? 116.617 110.654 73.328  1.00 70.11  ? 138 GLU B OE1 1 
ATOM 2821 O OE2 . GLU B 2 148 ? 116.994 108.556 73.847  1.00 72.22  ? 138 GLU B OE2 1 
ATOM 2822 N N   . LEU B 2 149 ? 111.734 111.341 69.863  1.00 66.90  ? 139 LEU B N   1 
ATOM 2823 C CA  . LEU B 2 149 ? 111.250 112.316 68.887  1.00 67.52  ? 139 LEU B CA  1 
ATOM 2824 C C   . LEU B 2 149 ? 111.546 113.717 69.407  1.00 66.47  ? 139 LEU B C   1 
ATOM 2825 O O   . LEU B 2 149 ? 110.855 114.226 70.294  1.00 70.46  ? 139 LEU B O   1 
ATOM 2826 C CB  . LEU B 2 149 ? 109.761 112.119 68.630  1.00 62.93  ? 139 LEU B CB  1 
ATOM 2827 C CG  . LEU B 2 149 ? 109.339 110.706 68.222  1.00 60.85  ? 139 LEU B CG  1 
ATOM 2828 C CD1 . LEU B 2 149 ? 107.835 110.634 68.033  1.00 66.09  ? 139 LEU B CD1 1 
ATOM 2829 C CD2 . LEU B 2 149 ? 110.064 110.267 66.961  1.00 66.13  ? 139 LEU B CD2 1 
ATOM 2830 N N   . ALA B 2 150 ? 112.580 114.342 68.853  1.00 64.01  ? 140 ALA B N   1 
ATOM 2831 C CA  . ALA B 2 150 ? 112.977 115.698 69.198  1.00 64.31  ? 140 ALA B CA  1 
ATOM 2832 C C   . ALA B 2 150 ? 112.548 116.671 68.108  1.00 69.94  ? 140 ALA B C   1 
ATOM 2833 O O   . ALA B 2 150 ? 112.437 116.307 66.934  1.00 74.36  ? 140 ALA B O   1 
ATOM 2834 C CB  . ALA B 2 150 ? 114.489 115.787 69.409  1.00 63.97  ? 140 ALA B CB  1 
ATOM 2835 N N   . GLY B 2 151 ? 112.323 117.922 68.503  1.00 73.62  ? 141 GLY B N   1 
ATOM 2836 C CA  . GLY B 2 151 ? 111.855 118.926 67.568  1.00 69.87  ? 141 GLY B CA  1 
ATOM 2837 C C   . GLY B 2 151 ? 110.893 119.936 68.158  1.00 70.89  ? 141 GLY B C   1 
ATOM 2838 O O   . GLY B 2 151 ? 110.817 121.073 67.683  1.00 74.84  ? 141 GLY B O   1 
ATOM 2839 N N   . HIS B 2 152 ? 110.153 119.542 69.190  1.00 55.72  ? 142 HIS B N   1 
ATOM 2840 C CA  . HIS B 2 152 ? 109.321 120.496 69.908  1.00 58.79  ? 142 HIS B CA  1 
ATOM 2841 C C   . HIS B 2 152 ? 110.182 121.397 70.785  1.00 65.46  ? 142 HIS B C   1 
ATOM 2842 O O   . HIS B 2 152 ? 111.159 120.951 71.394  1.00 66.24  ? 142 HIS B O   1 
ATOM 2843 C CB  . HIS B 2 152 ? 108.281 119.766 70.756  1.00 55.83  ? 142 HIS B CB  1 
ATOM 2844 C CG  . HIS B 2 152 ? 107.053 119.372 69.996  1.00 57.13  ? 142 HIS B CG  1 
ATOM 2845 N ND1 . HIS B 2 152 ? 106.273 120.284 69.318  1.00 54.55  ? 142 HIS B ND1 1 
ATOM 2846 C CD2 . HIS B 2 152 ? 106.467 118.165 69.810  1.00 61.79  ? 142 HIS B CD2 1 
ATOM 2847 C CE1 . HIS B 2 152 ? 105.261 119.656 68.746  1.00 65.48  ? 142 HIS B CE1 1 
ATOM 2848 N NE2 . HIS B 2 152 ? 105.356 118.369 69.029  1.00 63.92  ? 142 HIS B NE2 1 
ATOM 2849 N N   . THR B 2 153 ? 109.810 122.674 70.850  1.00 67.75  ? 143 THR B N   1 
ATOM 2850 C CA  . THR B 2 153 ? 110.506 123.655 71.672  1.00 63.45  ? 143 THR B CA  1 
ATOM 2851 C C   . THR B 2 153 ? 109.783 123.947 72.981  1.00 58.73  ? 143 THR B C   1 
ATOM 2852 O O   . THR B 2 153 ? 110.150 124.895 73.682  1.00 56.47  ? 143 THR B O   1 
ATOM 2853 C CB  . THR B 2 153 ? 110.715 124.953 70.888  1.00 62.44  ? 143 THR B CB  1 
ATOM 2854 O OG1 . THR B 2 153 ? 109.468 125.389 70.334  1.00 62.27  ? 143 THR B OG1 1 
ATOM 2855 C CG2 . THR B 2 153 ? 111.714 124.737 69.762  1.00 58.95  ? 143 THR B CG2 1 
ATOM 2856 N N   . GLY B 2 154 ? 108.764 123.157 73.324  1.00 61.36  ? 144 GLY B N   1 
ATOM 2857 C CA  . GLY B 2 154 ? 108.096 123.276 74.602  1.00 61.98  ? 144 GLY B CA  1 
ATOM 2858 C C   . GLY B 2 154 ? 107.838 121.906 75.195  1.00 61.42  ? 144 GLY B C   1 
ATOM 2859 O O   . GLY B 2 154 ? 108.144 120.880 74.583  1.00 66.52  ? 144 GLY B O   1 
ATOM 2860 N N   . TYR B 2 155 ? 107.264 121.904 76.395  1.00 57.15  ? 145 TYR B N   1 
ATOM 2861 C CA  . TYR B 2 155 ? 107.002 120.643 77.072  1.00 64.23  ? 145 TYR B CA  1 
ATOM 2862 C C   . TYR B 2 155 ? 105.966 119.830 76.305  1.00 68.98  ? 145 TYR B C   1 
ATOM 2863 O O   . TYR B 2 155 ? 105.071 120.376 75.656  1.00 67.55  ? 145 TYR B O   1 
ATOM 2864 C CB  . TYR B 2 155 ? 106.530 120.892 78.504  1.00 63.17  ? 145 TYR B CB  1 
ATOM 2865 C CG  . TYR B 2 155 ? 105.229 121.659 78.620  1.00 65.19  ? 145 TYR B CG  1 
ATOM 2866 C CD1 . TYR B 2 155 ? 105.216 123.046 78.618  1.00 64.38  ? 145 TYR B CD1 1 
ATOM 2867 C CD2 . TYR B 2 155 ? 104.018 120.998 78.756  1.00 59.89  ? 145 TYR B CD2 1 
ATOM 2868 C CE1 . TYR B 2 155 ? 104.033 123.750 78.731  1.00 64.07  ? 145 TYR B CE1 1 
ATOM 2869 C CE2 . TYR B 2 155 ? 102.831 121.695 78.870  1.00 60.18  ? 145 TYR B CE2 1 
ATOM 2870 C CZ  . TYR B 2 155 ? 102.845 123.070 78.858  1.00 64.67  ? 145 TYR B CZ  1 
ATOM 2871 O OH  . TYR B 2 155 ? 101.667 123.767 78.971  1.00 69.42  ? 145 TYR B OH  1 
ATOM 2872 N N   . LEU B 2 156 ? 106.089 118.509 76.398  1.00 65.09  ? 146 LEU B N   1 
ATOM 2873 C CA  . LEU B 2 156 ? 105.149 117.596 75.760  1.00 55.40  ? 146 LEU B CA  1 
ATOM 2874 C C   . LEU B 2 156 ? 103.951 117.377 76.674  1.00 52.32  ? 146 LEU B C   1 
ATOM 2875 O O   . LEU B 2 156 ? 104.102 116.892 77.800  1.00 44.10  ? 146 LEU B O   1 
ATOM 2876 C CB  . LEU B 2 156 ? 105.822 116.268 75.425  1.00 53.21  ? 146 LEU B CB  1 
ATOM 2877 C CG  . LEU B 2 156 ? 106.060 116.019 73.935  1.00 51.43  ? 146 LEU B CG  1 
ATOM 2878 C CD1 . LEU B 2 156 ? 107.350 116.680 73.478  1.00 52.51  ? 146 LEU B CD1 1 
ATOM 2879 C CD2 . LEU B 2 156 ? 106.080 114.532 73.647  1.00 60.05  ? 146 LEU B CD2 1 
ATOM 2880 N N   . SER B 2 157 ? 102.765 117.732 76.186  1.00 54.49  ? 147 SER B N   1 
ATOM 2881 C CA  . SER B 2 157 ? 101.548 117.639 76.978  1.00 54.85  ? 147 SER B CA  1 
ATOM 2882 C C   . SER B 2 157 ? 100.706 116.412 76.654  1.00 62.15  ? 147 SER B C   1 
ATOM 2883 O O   . SER B 2 157 ? 100.050 115.877 77.553  1.00 72.43  ? 147 SER B O   1 
ATOM 2884 C CB  . SER B 2 157 ? 100.704 118.902 76.793  1.00 50.06  ? 147 SER B CB  1 
ATOM 2885 O OG  . SER B 2 157 ? 100.323 119.068 75.439  1.00 57.97  ? 147 SER B OG  1 
ATOM 2886 N N   . CYS B 2 158 ? 100.702 115.951 75.404  1.00 47.85  ? 148 CYS B N   1 
ATOM 2887 C CA  . CYS B 2 158 ? 99.937  114.762 75.053  1.00 40.29  ? 148 CYS B CA  1 
ATOM 2888 C C   . CYS B 2 158 ? 100.532 114.121 73.808  1.00 47.73  ? 148 CYS B C   1 
ATOM 2889 O O   . CYS B 2 158 ? 101.157 114.793 72.983  1.00 64.52  ? 148 CYS B O   1 
ATOM 2890 C CB  . CYS B 2 158 ? 98.459  115.096 74.826  1.00 41.30  ? 148 CYS B CB  1 
ATOM 2891 S SG  . CYS B 2 158 ? 97.432  113.686 74.366  1.00 54.60  ? 148 CYS B SG  1 
ATOM 2892 N N   . CYS B 2 159 ? 100.327 112.810 73.688  1.00 51.82  ? 149 CYS B N   1 
ATOM 2893 C CA  . CYS B 2 159 ? 100.784 112.039 72.540  1.00 41.52  ? 149 CYS B CA  1 
ATOM 2894 C C   . CYS B 2 159 ? 99.849  110.853 72.354  1.00 38.05  ? 149 CYS B C   1 
ATOM 2895 O O   . CYS B 2 159 ? 99.375  110.274 73.334  1.00 44.62  ? 149 CYS B O   1 
ATOM 2896 C CB  . CYS B 2 159 ? 102.230 111.562 72.717  1.00 37.99  ? 149 CYS B CB  1 
ATOM 2897 S SG  . CYS B 2 159 ? 102.506 110.511 74.157  1.00 49.23  ? 149 CYS B SG  1 
ATOM 2898 N N   . ARG B 2 160 ? 99.591  110.494 71.097  1.00 33.78  ? 150 ARG B N   1 
ATOM 2899 C CA  . ARG B 2 160 ? 98.717  109.370 70.781  1.00 42.80  ? 150 ARG B CA  1 
ATOM 2900 C C   . ARG B 2 160 ? 99.215  108.682 69.519  1.00 44.78  ? 150 ARG B C   1 
ATOM 2901 O O   . ARG B 2 160 ? 99.460  109.346 68.508  1.00 50.70  ? 150 ARG B O   1 
ATOM 2902 C CB  . ARG B 2 160 ? 97.266  109.832 70.591  1.00 43.00  ? 150 ARG B CB  1 
ATOM 2903 C CG  . ARG B 2 160 ? 96.566  110.274 71.864  1.00 44.89  ? 150 ARG B CG  1 
ATOM 2904 C CD  . ARG B 2 160 ? 96.374  109.113 72.825  1.00 45.70  ? 150 ARG B CD  1 
ATOM 2905 N NE  . ARG B 2 160 ? 95.887  109.559 74.124  1.00 49.27  ? 150 ARG B NE  1 
ATOM 2906 C CZ  . ARG B 2 160 ? 96.661  109.785 75.177  1.00 47.42  ? 150 ARG B CZ  1 
ATOM 2907 N NH1 . ARG B 2 160 ? 97.970  109.604 75.123  1.00 45.01  ? 150 ARG B NH1 1 
ATOM 2908 N NH2 . ARG B 2 160 ? 96.108  110.201 76.313  1.00 48.36  ? 150 ARG B NH2 1 
ATOM 2909 N N   . PHE B 2 161 ? 99.354  107.359 69.581  1.00 49.10  ? 151 PHE B N   1 
ATOM 2910 C CA  . PHE B 2 161 ? 99.728  106.585 68.405  1.00 55.03  ? 151 PHE B CA  1 
ATOM 2911 C C   . PHE B 2 161 ? 98.565  106.472 67.426  1.00 58.16  ? 151 PHE B C   1 
ATOM 2912 O O   . PHE B 2 161 ? 97.420  106.239 67.821  1.00 56.70  ? 151 PHE B O   1 
ATOM 2913 C CB  . PHE B 2 161 ? 100.175 105.179 68.806  1.00 53.29  ? 151 PHE B CB  1 
ATOM 2914 C CG  . PHE B 2 161 ? 101.559 105.114 69.377  1.00 42.76  ? 151 PHE B CG  1 
ATOM 2915 C CD1 . PHE B 2 161 ? 102.666 105.091 68.547  1.00 48.44  ? 151 PHE B CD1 1 
ATOM 2916 C CD2 . PHE B 2 161 ? 101.751 105.041 70.744  1.00 47.50  ? 151 PHE B CD2 1 
ATOM 2917 C CE1 . PHE B 2 161 ? 103.937 105.018 69.072  1.00 57.01  ? 151 PHE B CE1 1 
ATOM 2918 C CE2 . PHE B 2 161 ? 103.019 104.964 71.272  1.00 56.51  ? 151 PHE B CE2 1 
ATOM 2919 C CZ  . PHE B 2 161 ? 104.114 104.955 70.437  1.00 54.16  ? 151 PHE B CZ  1 
ATOM 2920 N N   . LEU B 2 162 ? 98.870  106.624 66.137  1.00 57.02  ? 152 LEU B N   1 
ATOM 2921 C CA  . LEU B 2 162 ? 97.948  106.200 65.090  1.00 55.74  ? 152 LEU B CA  1 
ATOM 2922 C C   . LEU B 2 162 ? 98.222  104.764 64.666  1.00 59.56  ? 152 LEU B C   1 
ATOM 2923 O O   . LEU B 2 162 ? 97.284  103.993 64.438  1.00 58.33  ? 152 LEU B O   1 
ATOM 2924 C CB  . LEU B 2 162 ? 98.042  107.124 63.872  1.00 56.83  ? 152 LEU B CB  1 
ATOM 2925 C CG  . LEU B 2 162 ? 97.856  108.627 64.080  1.00 58.91  ? 152 LEU B CG  1 
ATOM 2926 C CD1 . LEU B 2 162 ? 99.205  109.305 64.211  1.00 55.39  ? 152 LEU B CD1 1 
ATOM 2927 C CD2 . LEU B 2 162 ? 97.052  109.234 62.941  1.00 62.98  ? 152 LEU B CD2 1 
ATOM 2928 N N   . ASP B 2 163 ? 99.495  104.398 64.563  1.00 73.95  ? 153 ASP B N   1 
ATOM 2929 C CA  . ASP B 2 163 ? 99.925  103.033 64.290  1.00 72.49  ? 153 ASP B CA  1 
ATOM 2930 C C   . ASP B 2 163 ? 101.359 102.894 64.789  1.00 72.87  ? 153 ASP B C   1 
ATOM 2931 O O   . ASP B 2 163 ? 101.858 103.746 65.532  1.00 73.49  ? 153 ASP B O   1 
ATOM 2932 C CB  . ASP B 2 163 ? 99.789  102.701 62.800  1.00 72.46  ? 153 ASP B CB  1 
ATOM 2933 C CG  . ASP B 2 163 ? 100.585 103.643 61.918  1.00 80.36  ? 153 ASP B CG  1 
ATOM 2934 O OD1 . ASP B 2 163 ? 101.817 103.467 61.812  1.00 81.41  ? 153 ASP B OD1 1 
ATOM 2935 O OD2 . ASP B 2 163 ? 99.978  104.562 61.330  1.00 82.29  ? 153 ASP B OD2 1 
ATOM 2936 N N   . ASP B 2 164 ? 102.030 101.816 64.380  1.00 74.55  ? 154 ASP B N   1 
ATOM 2937 C CA  . ASP B 2 164 ? 103.398 101.584 64.831  1.00 74.78  ? 154 ASP B CA  1 
ATOM 2938 C C   . ASP B 2 164 ? 104.392 102.572 64.235  1.00 77.95  ? 154 ASP B C   1 
ATOM 2939 O O   . ASP B 2 164 ? 105.508 102.692 64.752  1.00 80.20  ? 154 ASP B O   1 
ATOM 2940 C CB  . ASP B 2 164 ? 103.827 100.154 64.498  1.00 75.55  ? 154 ASP B CB  1 
ATOM 2941 C CG  . ASP B 2 164 ? 103.105 99.120  65.337  1.00 78.58  ? 154 ASP B CG  1 
ATOM 2942 O OD1 . ASP B 2 164 ? 102.288 99.518  66.193  1.00 79.47  ? 154 ASP B OD1 1 
ATOM 2943 O OD2 . ASP B 2 164 ? 103.357 97.912  65.144  1.00 79.99  ? 154 ASP B OD2 1 
ATOM 2944 N N   . ASN B 2 165 ? 104.022 103.280 63.166  1.00 71.08  ? 155 ASN B N   1 
ATOM 2945 C CA  . ASN B 2 165 ? 104.949 104.180 62.496  1.00 72.13  ? 155 ASN B CA  1 
ATOM 2946 C C   . ASN B 2 165 ? 104.579 105.653 62.601  1.00 72.95  ? 155 ASN B C   1 
ATOM 2947 O O   . ASN B 2 165 ? 105.432 106.503 62.330  1.00 69.84  ? 155 ASN B O   1 
ATOM 2948 C CB  . ASN B 2 165 ? 105.069 103.803 61.011  1.00 67.20  ? 155 ASN B CB  1 
ATOM 2949 C CG  . ASN B 2 165 ? 106.307 104.385 60.359  1.00 68.46  ? 155 ASN B CG  1 
ATOM 2950 O OD1 . ASN B 2 165 ? 107.285 104.706 61.034  1.00 71.31  ? 155 ASN B OD1 1 
ATOM 2951 N ND2 . ASN B 2 165 ? 106.272 104.523 59.039  1.00 70.94  ? 155 ASN B ND2 1 
ATOM 2952 N N   . GLN B 2 166 ? 103.345 105.980 62.979  1.00 70.96  ? 156 GLN B N   1 
ATOM 2953 C CA  . GLN B 2 166 ? 102.902 107.365 63.065  1.00 65.03  ? 156 GLN B CA  1 
ATOM 2954 C C   . GLN B 2 166 ? 102.381 107.670 64.462  1.00 61.64  ? 156 GLN B C   1 
ATOM 2955 O O   . GLN B 2 166 ? 101.688 106.850 65.072  1.00 69.14  ? 156 GLN B O   1 
ATOM 2956 C CB  . GLN B 2 166 ? 101.816 107.659 62.027  1.00 61.54  ? 156 GLN B CB  1 
ATOM 2957 C CG  . GLN B 2 166 ? 102.307 107.589 60.591  1.00 63.12  ? 156 GLN B CG  1 
ATOM 2958 C CD  . GLN B 2 166 ? 101.241 107.984 59.590  1.00 69.50  ? 156 GLN B CD  1 
ATOM 2959 O OE1 . GLN B 2 166 ? 100.081 108.189 59.948  1.00 76.47  ? 156 GLN B OE1 1 
ATOM 2960 N NE2 . GLN B 2 166 ? 101.629 108.089 58.324  1.00 65.86  ? 156 GLN B NE2 1 
ATOM 2961 N N   . ILE B 2 167 ? 102.720 108.856 64.963  1.00 50.40  ? 157 ILE B N   1 
ATOM 2962 C CA  . ILE B 2 167 ? 102.220 109.340 66.245  1.00 51.53  ? 157 ILE B CA  1 
ATOM 2963 C C   . ILE B 2 167 ? 102.053 110.851 66.152  1.00 55.84  ? 157 ILE B C   1 
ATOM 2964 O O   . ILE B 2 167 ? 102.850 111.535 65.504  1.00 63.29  ? 157 ILE B O   1 
ATOM 2965 C CB  . ILE B 2 167 ? 103.160 108.932 67.401  1.00 50.97  ? 157 ILE B CB  1 
ATOM 2966 C CG1 . ILE B 2 167 ? 102.668 109.499 68.735  1.00 57.75  ? 157 ILE B CG1 1 
ATOM 2967 C CG2 . ILE B 2 167 ? 104.585 109.373 67.114  1.00 45.96  ? 157 ILE B CG2 1 
ATOM 2968 C CD1 . ILE B 2 167 ? 103.556 109.159 69.910  1.00 54.82  ? 157 ILE B CD1 1 
ATOM 2969 N N   . VAL B 2 168 ? 101.010 111.372 66.795  1.00 44.18  ? 158 VAL B N   1 
ATOM 2970 C CA  . VAL B 2 168 ? 100.758 112.807 66.868  1.00 42.86  ? 158 VAL B CA  1 
ATOM 2971 C C   . VAL B 2 168 ? 101.033 113.261 68.294  1.00 48.08  ? 158 VAL B C   1 
ATOM 2972 O O   . VAL B 2 168 ? 100.559 112.639 69.252  1.00 55.34  ? 158 VAL B O   1 
ATOM 2973 C CB  . VAL B 2 168 ? 99.319  113.154 66.447  1.00 39.71  ? 158 VAL B CB  1 
ATOM 2974 C CG1 . VAL B 2 168 ? 99.029  114.626 66.695  1.00 45.97  ? 158 VAL B CG1 1 
ATOM 2975 C CG2 . VAL B 2 168 ? 99.101  112.814 64.984  1.00 56.41  ? 158 VAL B CG2 1 
ATOM 2976 N N   . THR B 2 169 ? 101.795 114.343 68.434  1.00 53.38  ? 159 THR B N   1 
ATOM 2977 C CA  . THR B 2 169 ? 102.131 114.908 69.733  1.00 51.07  ? 159 THR B CA  1 
ATOM 2978 C C   . THR B 2 169 ? 101.706 116.368 69.789  1.00 54.85  ? 159 THR B C   1 
ATOM 2979 O O   . THR B 2 169 ? 101.822 117.097 68.798  1.00 60.66  ? 159 THR B O   1 
ATOM 2980 C CB  . THR B 2 169 ? 103.634 114.797 70.014  1.00 50.43  ? 159 THR B CB  1 
ATOM 2981 O OG1 . THR B 2 169 ? 104.362 115.529 69.021  1.00 54.83  ? 159 THR B OG1 1 
ATOM 2982 C CG2 . THR B 2 169 ? 104.079 113.344 69.986  1.00 48.15  ? 159 THR B CG2 1 
ATOM 2983 N N   . SER B 2 170 ? 101.214 116.790 70.950  1.00 55.61  ? 160 SER B N   1 
ATOM 2984 C CA  . SER B 2 170 ? 100.956 118.194 71.234  1.00 57.45  ? 160 SER B CA  1 
ATOM 2985 C C   . SER B 2 170 ? 101.935 118.686 72.290  1.00 59.70  ? 160 SER B C   1 
ATOM 2986 O O   . SER B 2 170 ? 102.273 117.954 73.226  1.00 58.51  ? 160 SER B O   1 
ATOM 2987 C CB  . SER B 2 170 ? 99.517  118.403 71.710  1.00 59.65  ? 160 SER B CB  1 
ATOM 2988 O OG  . SER B 2 170 ? 99.257  117.666 72.891  1.00 67.73  ? 160 SER B OG  1 
ATOM 2989 N N   . SER B 2 171 ? 102.381 119.929 72.142  1.00 66.47  ? 161 SER B N   1 
ATOM 2990 C CA  . SER B 2 171 ? 103.408 120.494 73.001  1.00 63.64  ? 161 SER B CA  1 
ATOM 2991 C C   . SER B 2 171 ? 102.953 121.849 73.528  1.00 60.32  ? 161 SER B C   1 
ATOM 2992 O O   . SER B 2 171 ? 101.986 122.441 73.044  1.00 64.91  ? 161 SER B O   1 
ATOM 2993 C CB  . SER B 2 171 ? 104.747 120.627 72.265  1.00 67.77  ? 161 SER B CB  1 
ATOM 2994 O OG  . SER B 2 171 ? 105.742 121.173 73.113  1.00 69.57  ? 161 SER B OG  1 
ATOM 2995 N N   . GLY B 2 172 ? 103.678 122.339 74.529  1.00 57.04  ? 162 GLY B N   1 
ATOM 2996 C CA  . GLY B 2 172 ? 103.496 123.674 75.056  1.00 64.51  ? 162 GLY B CA  1 
ATOM 2997 C C   . GLY B 2 172 ? 104.128 124.783 74.252  1.00 72.10  ? 162 GLY B C   1 
ATOM 2998 O O   . GLY B 2 172 ? 103.996 125.953 74.621  1.00 75.07  ? 162 GLY B O   1 
ATOM 2999 N N   . ASP B 2 173 ? 104.812 124.456 73.156  1.00 70.77  ? 163 ASP B N   1 
ATOM 3000 C CA  . ASP B 2 173 ? 105.351 125.455 72.245  1.00 62.86  ? 163 ASP B CA  1 
ATOM 3001 C C   . ASP B 2 173 ? 104.339 125.897 71.196  1.00 63.96  ? 163 ASP B C   1 
ATOM 3002 O O   . ASP B 2 173 ? 104.739 126.404 70.140  1.00 68.53  ? 163 ASP B O   1 
ATOM 3003 C CB  . ASP B 2 173 ? 106.619 124.929 71.566  1.00 66.56  ? 163 ASP B CB  1 
ATOM 3004 C CG  . ASP B 2 173 ? 106.377 123.668 70.751  1.00 70.79  ? 163 ASP B CG  1 
ATOM 3005 O OD1 . ASP B 2 173 ? 105.209 123.257 70.587  1.00 72.67  ? 163 ASP B OD1 1 
ATOM 3006 O OD2 . ASP B 2 173 ? 107.367 123.086 70.262  1.00 70.30  ? 163 ASP B OD2 1 
ATOM 3007 N N   . THR B 2 174 ? 103.048 125.680 71.452  1.00 67.45  ? 164 THR B N   1 
ATOM 3008 C CA  . THR B 2 174 ? 101.914 126.141 70.652  1.00 69.14  ? 164 THR B CA  1 
ATOM 3009 C C   . THR B 2 174 ? 101.741 125.360 69.356  1.00 71.83  ? 164 THR B C   1 
ATOM 3010 O O   . THR B 2 174 ? 100.924 125.753 68.514  1.00 75.41  ? 164 THR B O   1 
ATOM 3011 C CB  . THR B 2 174 ? 101.996 127.640 70.323  1.00 67.84  ? 164 THR B CB  1 
ATOM 3012 O OG1 . THR B 2 174 ? 103.066 127.877 69.399  1.00 74.20  ? 164 THR B OG1 1 
ATOM 3013 C CG2 . THR B 2 174 ? 102.227 128.466 71.585  1.00 62.12  ? 164 THR B CG2 1 
ATOM 3014 N N   . THR B 2 175 ? 102.477 124.266 69.165  1.00 69.56  ? 165 THR B N   1 
ATOM 3015 C CA  . THR B 2 175 ? 102.417 123.508 67.924  1.00 72.15  ? 165 THR B CA  1 
ATOM 3016 C C   . THR B 2 175 ? 102.120 122.042 68.208  1.00 72.04  ? 165 THR B C   1 
ATOM 3017 O O   . THR B 2 175 ? 102.482 121.506 69.259  1.00 67.99  ? 165 THR B O   1 
ATOM 3018 C CB  . THR B 2 175 ? 103.729 123.616 67.132  1.00 73.64  ? 165 THR B CB  1 
ATOM 3019 O OG1 . THR B 2 175 ? 104.802 123.060 67.901  1.00 68.58  ? 165 THR B OG1 1 
ATOM 3020 C CG2 . THR B 2 175 ? 104.044 125.070 66.811  1.00 74.49  ? 165 THR B CG2 1 
ATOM 3021 N N   . CYS B 2 176 ? 101.455 121.401 67.250  1.00 77.41  ? 166 CYS B N   1 
ATOM 3022 C CA  . CYS B 2 176 ? 101.310 119.955 67.193  1.00 66.44  ? 166 CYS B CA  1 
ATOM 3023 C C   . CYS B 2 176 ? 102.137 119.409 66.036  1.00 69.28  ? 166 CYS B C   1 
ATOM 3024 O O   . CYS B 2 176 ? 102.391 120.111 65.053  1.00 77.66  ? 166 CYS B O   1 
ATOM 3025 C CB  . CYS B 2 176 ? 99.842  119.549 67.026  1.00 61.61  ? 166 CYS B CB  1 
ATOM 3026 S SG  . CYS B 2 176 ? 98.744  120.137 68.335  1.00 86.17  ? 166 CYS B SG  1 
ATOM 3027 N N   . ALA B 2 177 ? 102.573 118.158 66.160  1.00 50.53  ? 167 ALA B N   1 
ATOM 3028 C CA  . ALA B 2 177 ? 103.402 117.550 65.130  1.00 56.91  ? 167 ALA B CA  1 
ATOM 3029 C C   . ALA B 2 177 ? 102.945 116.127 64.846  1.00 62.12  ? 167 ALA B C   1 
ATOM 3030 O O   . ALA B 2 177 ? 102.505 115.405 65.744  1.00 72.19  ? 167 ALA B O   1 
ATOM 3031 C CB  . ALA B 2 177 ? 104.883 117.545 65.531  1.00 54.99  ? 167 ALA B CB  1 
ATOM 3032 N N   . LEU B 2 178 ? 103.057 115.738 63.579  1.00 63.52  ? 168 LEU B N   1 
ATOM 3033 C CA  . LEU B 2 178 ? 102.886 114.357 63.145  1.00 58.27  ? 168 LEU B CA  1 
ATOM 3034 C C   . LEU B 2 178 ? 104.261 113.776 62.847  1.00 60.88  ? 168 LEU B C   1 
ATOM 3035 O O   . LEU B 2 178 ? 105.043 114.379 62.105  1.00 75.81  ? 168 LEU B O   1 
ATOM 3036 C CB  . LEU B 2 178 ? 101.993 114.275 61.907  1.00 64.41  ? 168 LEU B CB  1 
ATOM 3037 C CG  . LEU B 2 178 ? 101.928 112.911 61.214  1.00 63.79  ? 168 LEU B CG  1 
ATOM 3038 C CD1 . LEU B 2 178 ? 101.303 111.865 62.123  1.00 60.35  ? 168 LEU B CD1 1 
ATOM 3039 C CD2 . LEU B 2 178 ? 101.181 113.005 59.892  1.00 68.37  ? 168 LEU B CD2 1 
ATOM 3040 N N   . TRP B 2 179 ? 104.553 112.611 63.417  1.00 47.34  ? 169 TRP B N   1 
ATOM 3041 C CA  . TRP B 2 179 ? 105.891 112.044 63.362  1.00 57.28  ? 169 TRP B CA  1 
ATOM 3042 C C   . TRP B 2 179 ? 105.914 110.759 62.546  1.00 58.09  ? 169 TRP B C   1 
ATOM 3043 O O   . TRP B 2 179 ? 104.969 109.964 62.587  1.00 63.86  ? 169 TRP B O   1 
ATOM 3044 C CB  . TRP B 2 179 ? 106.412 111.758 64.773  1.00 62.07  ? 169 TRP B CB  1 
ATOM 3045 C CG  . TRP B 2 179 ? 106.481 112.976 65.637  1.00 62.49  ? 169 TRP B CG  1 
ATOM 3046 C CD1 . TRP B 2 179 ? 105.447 113.560 66.310  1.00 66.70  ? 169 TRP B CD1 1 
ATOM 3047 C CD2 . TRP B 2 179 ? 107.639 113.769 65.913  1.00 59.82  ? 169 TRP B CD2 1 
ATOM 3048 N NE1 . TRP B 2 179 ? 105.892 114.664 66.995  1.00 71.72  ? 169 TRP B NE1 1 
ATOM 3049 C CE2 . TRP B 2 179 ? 107.234 114.815 66.767  1.00 64.69  ? 169 TRP B CE2 1 
ATOM 3050 C CE3 . TRP B 2 179 ? 108.980 113.695 65.524  1.00 56.89  ? 169 TRP B CE3 1 
ATOM 3051 C CZ2 . TRP B 2 179 ? 108.120 115.778 67.237  1.00 60.76  ? 169 TRP B CZ2 1 
ATOM 3052 C CZ3 . TRP B 2 179 ? 109.858 114.652 65.993  1.00 59.53  ? 169 TRP B CZ3 1 
ATOM 3053 C CH2 . TRP B 2 179 ? 109.425 115.680 66.840  1.00 57.23  ? 169 TRP B CH2 1 
ATOM 3054 N N   . ASP B 2 180 ? 107.002 110.565 61.802  1.00 69.49  ? 170 ASP B N   1 
ATOM 3055 C CA  . ASP B 2 180 ? 107.345 109.276 61.215  1.00 71.90  ? 170 ASP B CA  1 
ATOM 3056 C C   . ASP B 2 180 ? 108.343 108.610 62.154  1.00 71.87  ? 170 ASP B C   1 
ATOM 3057 O O   . ASP B 2 180 ? 109.489 109.056 62.267  1.00 70.33  ? 170 ASP B O   1 
ATOM 3058 C CB  . ASP B 2 180 ? 107.922 109.439 59.810  1.00 73.52  ? 170 ASP B CB  1 
ATOM 3059 C CG  . ASP B 2 180 ? 108.218 108.108 59.143  1.00 74.78  ? 170 ASP B CG  1 
ATOM 3060 O OD1 . ASP B 2 180 ? 107.264 107.447 58.681  1.00 76.32  ? 170 ASP B OD1 1 
ATOM 3061 O OD2 . ASP B 2 180 ? 109.403 107.720 59.083  1.00 77.89  ? 170 ASP B OD2 1 
ATOM 3062 N N   . ILE B 2 181 ? 107.905 107.549 62.833  1.00 67.84  ? 171 ILE B N   1 
ATOM 3063 C CA  . ILE B 2 181 ? 108.721 106.953 63.887  1.00 67.87  ? 171 ILE B CA  1 
ATOM 3064 C C   . ILE B 2 181 ? 109.976 106.311 63.307  1.00 69.74  ? 171 ILE B C   1 
ATOM 3065 O O   . ILE B 2 181 ? 111.053 106.370 63.911  1.00 69.90  ? 171 ILE B O   1 
ATOM 3066 C CB  . ILE B 2 181 ? 107.885 105.947 64.699  1.00 62.10  ? 171 ILE B CB  1 
ATOM 3067 C CG1 . ILE B 2 181 ? 106.664 106.642 65.305  1.00 55.94  ? 171 ILE B CG1 1 
ATOM 3068 C CG2 . ILE B 2 181 ? 108.725 105.311 65.792  1.00 63.83  ? 171 ILE B CG2 1 
ATOM 3069 C CD1 . ILE B 2 181 ? 105.771 105.724 66.105  1.00 60.27  ? 171 ILE B CD1 1 
ATOM 3070 N N   . GLU B 2 182 ? 109.865 105.697 62.126  1.00 75.55  ? 172 GLU B N   1 
ATOM 3071 C CA  . GLU B 2 182 ? 111.007 104.988 61.555  1.00 73.06  ? 172 GLU B CA  1 
ATOM 3072 C C   . GLU B 2 182 ? 112.159 105.934 61.238  1.00 77.62  ? 172 GLU B C   1 
ATOM 3073 O O   . GLU B 2 182 ? 113.323 105.617 61.512  1.00 76.28  ? 172 GLU B O   1 
ATOM 3074 C CB  . GLU B 2 182 ? 110.581 104.229 60.298  1.00 74.97  ? 172 GLU B CB  1 
ATOM 3075 C CG  . GLU B 2 182 ? 111.704 103.430 59.655  1.00 79.92  ? 172 GLU B CG  1 
ATOM 3076 C CD  . GLU B 2 182 ? 112.148 102.255 60.505  1.00 83.42  ? 172 GLU B CD  1 
ATOM 3077 O OE1 . GLU B 2 182 ? 111.358 101.804 61.361  1.00 82.34  ? 172 GLU B OE1 1 
ATOM 3078 O OE2 . GLU B 2 182 ? 113.290 101.785 60.321  1.00 83.91  ? 172 GLU B OE2 1 
ATOM 3079 N N   . THR B 2 183 ? 111.862 107.099 60.664  1.00 83.84  ? 173 THR B N   1 
ATOM 3080 C CA  . THR B 2 183 ? 112.900 108.067 60.338  1.00 81.56  ? 173 THR B CA  1 
ATOM 3081 C C   . THR B 2 183 ? 113.191 109.051 61.464  1.00 82.59  ? 173 THR B C   1 
ATOM 3082 O O   . THR B 2 183 ? 114.212 109.745 61.406  1.00 80.83  ? 173 THR B O   1 
ATOM 3083 C CB  . THR B 2 183 ? 112.515 108.851 59.077  1.00 75.70  ? 173 THR B CB  1 
ATOM 3084 O OG1 . THR B 2 183 ? 111.231 109.459 59.263  1.00 76.02  ? 173 THR B OG1 1 
ATOM 3085 C CG2 . THR B 2 183 ? 112.464 107.929 57.870  1.00 73.56  ? 173 THR B CG2 1 
ATOM 3086 N N   . GLY B 2 184 ? 112.332 109.132 62.478  1.00 85.62  ? 174 GLY B N   1 
ATOM 3087 C CA  . GLY B 2 184 ? 112.577 110.042 63.578  1.00 83.76  ? 174 GLY B CA  1 
ATOM 3088 C C   . GLY B 2 184 ? 112.326 111.498 63.268  1.00 88.54  ? 174 GLY B C   1 
ATOM 3089 O O   . GLY B 2 184 ? 112.703 112.361 64.067  1.00 89.98  ? 174 GLY B O   1 
ATOM 3090 N N   . GLN B 2 185 ? 111.702 111.800 62.134  1.00 89.58  ? 175 GLN B N   1 
ATOM 3091 C CA  . GLN B 2 185 ? 111.447 113.164 61.703  1.00 87.56  ? 175 GLN B CA  1 
ATOM 3092 C C   . GLN B 2 185 ? 109.952 113.451 61.725  1.00 81.44  ? 175 GLN B C   1 
ATOM 3093 O O   . GLN B 2 185 ? 109.128 112.568 61.473  1.00 81.52  ? 175 GLN B O   1 
ATOM 3094 C CB  . GLN B 2 185 ? 112.005 113.413 60.298  1.00 87.08  ? 175 GLN B CB  1 
ATOM 3095 C CG  . GLN B 2 185 ? 113.507 113.197 60.181  1.00 86.71  ? 175 GLN B CG  1 
ATOM 3096 C CD  . GLN B 2 185 ? 114.308 114.208 60.979  1.00 88.36  ? 175 GLN B CD  1 
ATOM 3097 O OE1 . GLN B 2 185 ? 113.835 115.307 61.266  1.00 89.13  ? 175 GLN B OE1 1 
ATOM 3098 N NE2 . GLN B 2 185 ? 115.531 113.838 61.343  1.00 86.93  ? 175 GLN B NE2 1 
ATOM 3099 N N   . GLN B 2 186 ? 109.610 114.701 62.028  1.00 64.48  ? 176 GLN B N   1 
ATOM 3100 C CA  . GLN B 2 186 ? 108.219 115.135 62.015  1.00 64.84  ? 176 GLN B CA  1 
ATOM 3101 C C   . GLN B 2 186 ? 107.826 115.482 60.584  1.00 63.90  ? 176 GLN B C   1 
ATOM 3102 O O   . GLN B 2 186 ? 108.332 116.449 60.005  1.00 71.91  ? 176 GLN B O   1 
ATOM 3103 C CB  . GLN B 2 186 ? 108.015 116.323 62.952  1.00 69.24  ? 176 GLN B CB  1 
ATOM 3104 C CG  . GLN B 2 186 ? 109.074 117.412 62.846  1.00 73.11  ? 176 GLN B CG  1 
ATOM 3105 C CD  . GLN B 2 186 ? 108.759 118.620 63.708  1.00 76.41  ? 176 GLN B CD  1 
ATOM 3106 O OE1 . GLN B 2 186 ? 107.866 118.577 64.554  1.00 74.90  ? 176 GLN B OE1 1 
ATOM 3107 N NE2 . GLN B 2 186 ? 109.492 119.707 63.494  1.00 72.49  ? 176 GLN B NE2 1 
ATOM 3108 N N   . THR B 2 187 ? 106.927 114.683 60.006  1.00 60.94  ? 177 THR B N   1 
ATOM 3109 C CA  . THR B 2 187 ? 106.527 114.903 58.620  1.00 66.32  ? 177 THR B CA  1 
ATOM 3110 C C   . THR B 2 187 ? 105.679 116.159 58.494  1.00 65.09  ? 177 THR B C   1 
ATOM 3111 O O   . THR B 2 187 ? 105.811 116.912 57.522  1.00 70.74  ? 177 THR B O   1 
ATOM 3112 C CB  . THR B 2 187 ? 105.764 113.690 58.087  1.00 66.34  ? 177 THR B CB  1 
ATOM 3113 O OG1 . THR B 2 187 ? 104.570 113.499 58.856  1.00 64.86  ? 177 THR B OG1 1 
ATOM 3114 C CG2 . THR B 2 187 ? 106.622 112.440 58.178  1.00 68.52  ? 177 THR B CG2 1 
ATOM 3115 N N   . THR B 2 188 ? 104.803 116.400 59.465  1.00 54.95  ? 178 THR B N   1 
ATOM 3116 C CA  . THR B 2 188 ? 103.899 117.537 59.445  1.00 62.59  ? 178 THR B CA  1 
ATOM 3117 C C   . THR B 2 188 ? 103.991 118.283 60.767  1.00 66.05  ? 178 THR B C   1 
ATOM 3118 O O   . THR B 2 188 ? 104.094 117.667 61.832  1.00 69.20  ? 178 THR B O   1 
ATOM 3119 C CB  . THR B 2 188 ? 102.454 117.085 59.201  1.00 62.76  ? 178 THR B CB  1 
ATOM 3120 O OG1 . THR B 2 188 ? 102.396 116.269 58.023  1.00 66.03  ? 178 THR B OG1 1 
ATOM 3121 C CG2 . THR B 2 188 ? 101.547 118.281 59.027  1.00 61.22  ? 178 THR B CG2 1 
ATOM 3122 N N   . THR B 2 189 ? 103.950 119.611 60.690  1.00 69.62  ? 179 THR B N   1 
ATOM 3123 C CA  . THR B 2 189 ? 103.897 120.474 61.861  1.00 72.08  ? 179 THR B CA  1 
ATOM 3124 C C   . THR B 2 189 ? 102.587 121.245 61.830  1.00 71.41  ? 179 THR B C   1 
ATOM 3125 O O   . THR B 2 189 ? 102.246 121.854 60.811  1.00 70.91  ? 179 THR B O   1 
ATOM 3126 C CB  . THR B 2 189 ? 105.085 121.440 61.899  1.00 76.53  ? 179 THR B CB  1 
ATOM 3127 O OG1 . THR B 2 189 ? 106.309 120.697 61.858  1.00 77.77  ? 179 THR B OG1 1 
ATOM 3128 C CG2 . THR B 2 189 ? 105.050 122.277 63.169  1.00 72.30  ? 179 THR B CG2 1 
ATOM 3129 N N   . PHE B 2 190 ? 101.861 121.219 62.943  1.00 79.44  ? 180 PHE B N   1 
ATOM 3130 C CA  . PHE B 2 190 ? 100.552 121.854 63.047  1.00 80.23  ? 180 PHE B CA  1 
ATOM 3131 C C   . PHE B 2 190 ? 100.693 123.132 63.865  1.00 79.68  ? 180 PHE B C   1 
ATOM 3132 O O   . PHE B 2 190 ? 100.838 123.078 65.091  1.00 78.67  ? 180 PHE B O   1 
ATOM 3133 C CB  . PHE B 2 190 ? 99.549  120.894 63.682  1.00 83.44  ? 180 PHE B CB  1 
ATOM 3134 C CG  . PHE B 2 190 ? 99.438  119.574 62.970  1.00 84.56  ? 180 PHE B CG  1 
ATOM 3135 C CD1 . PHE B 2 190 ? 98.539  119.405 61.931  1.00 81.44  ? 180 PHE B CD1 1 
ATOM 3136 C CD2 . PHE B 2 190 ? 100.233 118.502 63.342  1.00 83.06  ? 180 PHE B CD2 1 
ATOM 3137 C CE1 . PHE B 2 190 ? 98.436  118.194 61.276  1.00 82.62  ? 180 PHE B CE1 1 
ATOM 3138 C CE2 . PHE B 2 190 ? 100.134 117.288 62.690  1.00 79.14  ? 180 PHE B CE2 1 
ATOM 3139 C CZ  . PHE B 2 190 ? 99.235  117.134 61.656  1.00 80.84  ? 180 PHE B CZ  1 
ATOM 3140 N N   . THR B 2 191 ? 100.648 124.276 63.188  1.00 81.80  ? 181 THR B N   1 
ATOM 3141 C CA  . THR B 2 191 ? 100.818 125.576 63.818  1.00 80.29  ? 181 THR B CA  1 
ATOM 3142 C C   . THR B 2 191 ? 99.526  126.379 63.732  1.00 82.68  ? 181 THR B C   1 
ATOM 3143 O O   . THR B 2 191 ? 98.717  126.191 62.819  1.00 80.85  ? 181 THR B O   1 
ATOM 3144 C CB  . THR B 2 191 ? 101.959 126.361 63.162  1.00 80.22  ? 181 THR B CB  1 
ATOM 3145 O OG1 . THR B 2 191 ? 101.634 126.623 61.791  1.00 82.33  ? 181 THR B OG1 1 
ATOM 3146 C CG2 . THR B 2 191 ? 103.255 125.571 63.227  1.00 81.98  ? 181 THR B CG2 1 
ATOM 3147 N N   . GLY B 2 192 ? 99.349  127.293 64.684  1.00 83.79  ? 182 GLY B N   1 
ATOM 3148 C CA  . GLY B 2 192 ? 98.177  128.148 64.693  1.00 80.50  ? 182 GLY B CA  1 
ATOM 3149 C C   . GLY B 2 192 ? 97.653  128.488 66.074  1.00 80.38  ? 182 GLY B C   1 
ATOM 3150 O O   . GLY B 2 192 ? 96.941  129.482 66.242  1.00 84.84  ? 182 GLY B O   1 
ATOM 3151 N N   . HIS B 2 193 ? 98.001  127.679 67.071  1.00 72.89  ? 183 HIS B N   1 
ATOM 3152 C CA  . HIS B 2 193 ? 97.659  128.002 68.450  1.00 74.58  ? 183 HIS B CA  1 
ATOM 3153 C C   . HIS B 2 193 ? 98.538  129.125 68.981  1.00 77.08  ? 183 HIS B C   1 
ATOM 3154 O O   . HIS B 2 193 ? 99.742  129.176 68.714  1.00 77.59  ? 183 HIS B O   1 
ATOM 3155 C CB  . HIS B 2 193 ? 97.800  126.768 69.340  1.00 73.37  ? 183 HIS B CB  1 
ATOM 3156 C CG  . HIS B 2 193 ? 96.665  125.799 69.221  1.00 72.47  ? 183 HIS B CG  1 
ATOM 3157 N ND1 . HIS B 2 193 ? 95.404  126.070 69.706  1.00 73.16  ? 183 HIS B ND1 1 
ATOM 3158 C CD2 . HIS B 2 193 ? 96.600  124.561 68.677  1.00 76.31  ? 183 HIS B CD2 1 
ATOM 3159 C CE1 . HIS B 2 193 ? 94.612  125.041 69.467  1.00 77.17  ? 183 HIS B CE1 1 
ATOM 3160 N NE2 . HIS B 2 193 ? 95.312  124.112 68.842  1.00 76.44  ? 183 HIS B NE2 1 
ATOM 3161 N N   . THR B 2 194 ? 97.923  130.043 69.724  1.00 80.76  ? 184 THR B N   1 
ATOM 3162 C CA  . THR B 2 194 ? 98.640  131.143 70.353  1.00 79.33  ? 184 THR B CA  1 
ATOM 3163 C C   . THR B 2 194 ? 99.003  130.858 71.804  1.00 82.71  ? 184 THR B C   1 
ATOM 3164 O O   . THR B 2 194 ? 99.629  131.704 72.450  1.00 85.14  ? 184 THR B O   1 
ATOM 3165 C CB  . THR B 2 194 ? 97.812  132.431 70.274  1.00 78.73  ? 184 THR B CB  1 
ATOM 3166 O OG1 . THR B 2 194 ? 96.563  132.241 70.950  1.00 84.62  ? 184 THR B OG1 1 
ATOM 3167 C CG2 . THR B 2 194 ? 97.544  132.802 68.825  1.00 76.95  ? 184 THR B CG2 1 
ATOM 3168 N N   . GLY B 2 195 ? 98.628  129.691 72.333  1.00 83.73  ? 185 GLY B N   1 
ATOM 3169 C CA  . GLY B 2 195 ? 98.998  129.298 73.676  1.00 80.90  ? 185 GLY B CA  1 
ATOM 3170 C C   . GLY B 2 195 ? 99.511  127.868 73.710  1.00 82.66  ? 185 GLY B C   1 
ATOM 3171 O O   . GLY B 2 195 ? 99.540  127.172 72.693  1.00 88.28  ? 185 GLY B O   1 
ATOM 3172 N N   . ASP B 2 196 ? 99.901  127.447 74.911  1.00 75.54  ? 186 ASP B N   1 
ATOM 3173 C CA  . ASP B 2 196 ? 100.419 126.098 75.107  1.00 74.15  ? 186 ASP B CA  1 
ATOM 3174 C C   . ASP B 2 196 ? 99.323  125.073 74.841  1.00 73.88  ? 186 ASP B C   1 
ATOM 3175 O O   . ASP B 2 196 ? 98.276  125.093 75.495  1.00 77.51  ? 186 ASP B O   1 
ATOM 3176 C CB  . ASP B 2 196 ? 100.957 125.948 76.527  1.00 77.73  ? 186 ASP B CB  1 
ATOM 3177 C CG  . ASP B 2 196 ? 101.752 127.156 76.978  1.00 83.43  ? 186 ASP B CG  1 
ATOM 3178 O OD1 . ASP B 2 196 ? 102.367 127.820 76.118  1.00 82.80  ? 186 ASP B OD1 1 
ATOM 3179 O OD2 . ASP B 2 196 ? 101.757 127.445 78.193  1.00 86.31  ? 186 ASP B OD2 1 
ATOM 3180 N N   . VAL B 2 197 ? 99.572  124.164 73.902  1.00 67.33  ? 187 VAL B N   1 
ATOM 3181 C CA  . VAL B 2 197 ? 98.644  123.071 73.627  1.00 71.63  ? 187 VAL B CA  1 
ATOM 3182 C C   . VAL B 2 197 ? 98.796  122.012 74.712  1.00 70.34  ? 187 VAL B C   1 
ATOM 3183 O O   . VAL B 2 197 ? 99.890  121.479 74.926  1.00 71.66  ? 187 VAL B O   1 
ATOM 3184 C CB  . VAL B 2 197 ? 98.887  122.476 72.234  1.00 71.46  ? 187 VAL B CB  1 
ATOM 3185 C CG1 . VAL B 2 197 ? 97.758  121.534 71.862  1.00 67.25  ? 187 VAL B CG1 1 
ATOM 3186 C CG2 . VAL B 2 197 ? 99.028  123.586 71.203  1.00 72.19  ? 187 VAL B CG2 1 
ATOM 3187 N N   . MET B 2 198 ? 97.694  121.703 75.399  1.00 74.37  ? 188 MET B N   1 
ATOM 3188 C CA  . MET B 2 198 ? 97.736  120.823 76.560  1.00 75.48  ? 188 MET B CA  1 
ATOM 3189 C C   . MET B 2 198 ? 97.288  119.393 76.281  1.00 77.41  ? 188 MET B C   1 
ATOM 3190 O O   . MET B 2 198 ? 97.638  118.496 77.056  1.00 79.88  ? 188 MET B O   1 
ATOM 3191 C CB  . MET B 2 198 ? 96.883  121.402 77.694  1.00 80.90  ? 188 MET B CB  1 
ATOM 3192 C CG  . MET B 2 198 ? 97.400  122.726 78.235  1.00 80.76  ? 188 MET B CG  1 
ATOM 3193 S SD  . MET B 2 198 ? 99.089  122.620 78.858  1.00 89.78  ? 188 MET B SD  1 
ATOM 3194 C CE  . MET B 2 198 ? 98.903  121.381 80.138  1.00 81.99  ? 188 MET B CE  1 
ATOM 3195 N N   . SER B 2 199 ? 96.514  119.151 75.225  1.00 84.09  ? 189 SER B N   1 
ATOM 3196 C CA  . SER B 2 199 ? 96.006  117.806 74.985  1.00 86.12  ? 189 SER B CA  1 
ATOM 3197 C C   . SER B 2 199 ? 95.652  117.640 73.515  1.00 91.34  ? 189 SER B C   1 
ATOM 3198 O O   . SER B 2 199 ? 95.491  118.618 72.780  1.00 97.74  ? 189 SER B O   1 
ATOM 3199 C CB  . SER B 2 199 ? 94.791  117.506 75.870  1.00 81.23  ? 189 SER B CB  1 
ATOM 3200 O OG  . SER B 2 199 ? 93.778  118.481 75.695  1.00 85.73  ? 189 SER B OG  1 
ATOM 3201 N N   . LEU B 2 200 ? 95.530  116.378 73.098  1.00 71.47  ? 190 LEU B N   1 
ATOM 3202 C CA  . LEU B 2 200 ? 95.020  116.042 71.777  1.00 66.75  ? 190 LEU B CA  1 
ATOM 3203 C C   . LEU B 2 200 ? 94.269  114.721 71.858  1.00 67.14  ? 190 LEU B C   1 
ATOM 3204 O O   . LEU B 2 200 ? 94.527  113.897 72.740  1.00 72.66  ? 190 LEU B O   1 
ATOM 3205 C CB  . LEU B 2 200 ? 96.140  115.942 70.731  1.00 65.35  ? 190 LEU B CB  1 
ATOM 3206 C CG  . LEU B 2 200 ? 97.108  114.755 70.805  1.00 67.19  ? 190 LEU B CG  1 
ATOM 3207 C CD1 . LEU B 2 200 ? 96.652  113.595 69.925  1.00 74.63  ? 190 LEU B CD1 1 
ATOM 3208 C CD2 . LEU B 2 200 ? 98.504  115.179 70.420  1.00 65.54  ? 190 LEU B CD2 1 
ATOM 3209 N N   . SER B 2 201 ? 93.329  114.533 70.933  1.00 68.43  ? 191 SER B N   1 
ATOM 3210 C CA  . SER B 2 201 ? 92.584  113.288 70.815  1.00 67.42  ? 191 SER B CA  1 
ATOM 3211 C C   . SER B 2 201 ? 92.502  112.893 69.348  1.00 69.08  ? 191 SER B C   1 
ATOM 3212 O O   . SER B 2 201 ? 92.257  113.740 68.486  1.00 72.70  ? 191 SER B O   1 
ATOM 3213 C CB  . SER B 2 201 ? 91.176  113.415 71.406  1.00 67.70  ? 191 SER B CB  1 
ATOM 3214 O OG  . SER B 2 201 ? 90.467  112.193 71.297  1.00 72.12  ? 191 SER B OG  1 
ATOM 3215 N N   . LEU B 2 202 ? 92.707  111.608 69.070  1.00 69.31  ? 192 LEU B N   1 
ATOM 3216 C CA  . LEU B 2 202 ? 92.629  111.090 67.711  1.00 68.09  ? 192 LEU B CA  1 
ATOM 3217 C C   . LEU B 2 202 ? 91.213  110.641 67.379  1.00 69.49  ? 192 LEU B C   1 
ATOM 3218 O O   . LEU B 2 202 ? 90.517  110.062 68.218  1.00 73.84  ? 192 LEU B O   1 
ATOM 3219 C CB  . LEU B 2 202 ? 93.596  109.920 67.517  1.00 65.76  ? 192 LEU B CB  1 
ATOM 3220 C CG  . LEU B 2 202 ? 95.079  110.203 67.743  1.00 65.87  ? 192 LEU B CG  1 
ATOM 3221 C CD1 . LEU B 2 202 ? 95.907  109.013 67.300  1.00 70.13  ? 192 LEU B CD1 1 
ATOM 3222 C CD2 . LEU B 2 202 ? 95.502  111.455 67.002  1.00 76.02  ? 192 LEU B CD2 1 
ATOM 3223 N N   . ALA B 2 203 ? 90.792  110.920 66.149  1.00 82.03  ? 193 ALA B N   1 
ATOM 3224 C CA  . ALA B 2 203 ? 89.522  110.414 65.659  1.00 84.00  ? 193 ALA B CA  1 
ATOM 3225 C C   . ALA B 2 203 ? 89.594  108.899 65.467  1.00 86.42  ? 193 ALA B C   1 
ATOM 3226 O O   . ALA B 2 203 ? 90.676  108.342 65.262  1.00 87.37  ? 193 ALA B O   1 
ATOM 3227 C CB  . ALA B 2 203 ? 89.154  111.091 64.342  1.00 86.66  ? 193 ALA B CB  1 
ATOM 3228 N N   . PRO B 2 204 ? 88.453  108.205 65.551  1.00 92.05  ? 194 PRO B N   1 
ATOM 3229 C CA  . PRO B 2 204 ? 88.478  106.738 65.422  1.00 89.71  ? 194 PRO B CA  1 
ATOM 3230 C C   . PRO B 2 204 ? 89.087  106.246 64.119  1.00 87.30  ? 194 PRO B C   1 
ATOM 3231 O O   . PRO B 2 204 ? 89.715  105.181 64.106  1.00 85.02  ? 194 PRO B O   1 
ATOM 3232 C CB  . PRO B 2 204 ? 86.996  106.356 65.532  1.00 90.31  ? 194 PRO B CB  1 
ATOM 3233 C CG  . PRO B 2 204 ? 86.395  107.449 66.345  1.00 88.78  ? 194 PRO B CG  1 
ATOM 3234 C CD  . PRO B 2 204 ? 87.122  108.701 65.941  1.00 89.52  ? 194 PRO B CD  1 
ATOM 3235 N N   . ASP B 2 205 ? 88.923  106.986 63.024  1.00 90.29  ? 195 ASP B N   1 
ATOM 3236 C CA  . ASP B 2 205 ? 89.537  106.629 61.752  1.00 92.44  ? 195 ASP B CA  1 
ATOM 3237 C C   . ASP B 2 205 ? 90.959  107.156 61.614  1.00 93.38  ? 195 ASP B C   1 
ATOM 3238 O O   . ASP B 2 205 ? 91.605  106.890 60.595  1.00 92.17  ? 195 ASP B O   1 
ATOM 3239 C CB  . ASP B 2 205 ? 88.682  107.143 60.587  1.00 95.81  ? 195 ASP B CB  1 
ATOM 3240 C CG  . ASP B 2 205 ? 88.530  108.650 60.595  1.00 96.96  ? 195 ASP B CG  1 
ATOM 3241 O OD1 . ASP B 2 205 ? 88.579  109.249 61.689  1.00 91.78  ? 195 ASP B OD1 1 
ATOM 3242 O OD2 . ASP B 2 205 ? 88.362  109.236 59.505  1.00 100.01 ? 195 ASP B OD2 1 
ATOM 3243 N N   . THR B 2 206 ? 91.451  107.897 62.610  1.00 99.67  ? 196 THR B N   1 
ATOM 3244 C CA  . THR B 2 206 ? 92.821  108.418 62.640  1.00 99.65  ? 196 THR B CA  1 
ATOM 3245 C C   . THR B 2 206 ? 93.138  109.284 61.423  1.00 98.28  ? 196 THR B C   1 
ATOM 3246 O O   . THR B 2 206 ? 94.293  109.375 60.999  1.00 94.73  ? 196 THR B O   1 
ATOM 3247 C CB  . THR B 2 206 ? 93.850  107.288 62.766  1.00 96.51  ? 196 THR B CB  1 
ATOM 3248 O OG1 . THR B 2 206 ? 93.870  106.514 61.560  1.00 96.41  ? 196 THR B OG1 1 
ATOM 3249 C CG2 . THR B 2 206 ? 93.506  106.382 63.940  1.00 93.78  ? 196 THR B CG2 1 
ATOM 3250 N N   . ARG B 2 207 ? 92.121  109.927 60.848  1.00 100.51 ? 197 ARG B N   1 
ATOM 3251 C CA  . ARG B 2 207 ? 92.338  110.901 59.788  1.00 97.09  ? 197 ARG B CA  1 
ATOM 3252 C C   . ARG B 2 207 ? 92.327  112.339 60.286  1.00 96.15  ? 197 ARG B C   1 
ATOM 3253 O O   . ARG B 2 207 ? 92.833  113.223 59.586  1.00 96.96  ? 197 ARG B O   1 
ATOM 3254 C CB  . ARG B 2 207 ? 91.275  110.743 58.694  1.00 94.91  ? 197 ARG B CB  1 
ATOM 3255 C CG  . ARG B 2 207 ? 91.335  109.417 57.954  1.00 93.40  ? 197 ARG B CG  1 
ATOM 3256 C CD  . ARG B 2 207 ? 90.306  109.364 56.836  1.00 97.20  ? 197 ARG B CD  1 
ATOM 3257 N NE  . ARG B 2 207 ? 90.391  108.126 56.071  1.00 101.11 ? 197 ARG B NE  1 
ATOM 3258 C CZ  . ARG B 2 207 ? 91.169  107.952 55.012  1.00 101.43 ? 197 ARG B CZ  1 
ATOM 3259 N NH1 . ARG B 2 207 ? 91.948  108.921 54.559  1.00 99.36  ? 197 ARG B NH1 1 
ATOM 3260 N NH2 . ARG B 2 207 ? 91.163  106.777 54.389  1.00 101.88 ? 197 ARG B NH2 1 
ATOM 3261 N N   . LEU B 2 208 ? 91.769  112.590 61.468  1.00 82.07  ? 198 LEU B N   1 
ATOM 3262 C CA  . LEU B 2 208 ? 91.727  113.917 62.061  1.00 77.91  ? 198 LEU B CA  1 
ATOM 3263 C C   . LEU B 2 208 ? 92.115  113.827 63.530  1.00 79.71  ? 198 LEU B C   1 
ATOM 3264 O O   . LEU B 2 208 ? 92.054  112.760 64.145  1.00 84.04  ? 198 LEU B O   1 
ATOM 3265 C CB  . LEU B 2 208 ? 90.332  114.550 61.932  1.00 81.11  ? 198 LEU B CB  1 
ATOM 3266 C CG  . LEU B 2 208 ? 89.705  114.636 60.540  1.00 81.46  ? 198 LEU B CG  1 
ATOM 3267 C CD1 . LEU B 2 208 ? 88.273  115.137 60.633  1.00 82.83  ? 198 LEU B CD1 1 
ATOM 3268 C CD2 . LEU B 2 208 ? 90.525  115.538 59.634  1.00 80.44  ? 198 LEU B CD2 1 
ATOM 3269 N N   . PHE B 2 209 ? 92.515  114.966 64.092  1.00 74.35  ? 199 PHE B N   1 
ATOM 3270 C CA  . PHE B 2 209 ? 92.694  115.067 65.531  1.00 75.68  ? 199 PHE B CA  1 
ATOM 3271 C C   . PHE B 2 209 ? 92.435  116.499 65.975  1.00 75.44  ? 199 PHE B C   1 
ATOM 3272 O O   . PHE B 2 209 ? 92.726  117.454 65.250  1.00 79.51  ? 199 PHE B O   1 
ATOM 3273 C CB  . PHE B 2 209 ? 94.094  114.611 65.968  1.00 71.13  ? 199 PHE B CB  1 
ATOM 3274 C CG  . PHE B 2 209 ? 95.199  115.547 65.567  1.00 68.14  ? 199 PHE B CG  1 
ATOM 3275 C CD1 . PHE B 2 209 ? 95.738  115.498 64.293  1.00 76.73  ? 199 PHE B CD1 1 
ATOM 3276 C CD2 . PHE B 2 209 ? 95.711  116.464 66.471  1.00 71.97  ? 199 PHE B CD2 1 
ATOM 3277 C CE1 . PHE B 2 209 ? 96.760  116.352 63.926  1.00 78.71  ? 199 PHE B CE1 1 
ATOM 3278 C CE2 . PHE B 2 209 ? 96.732  117.321 66.108  1.00 77.53  ? 199 PHE B CE2 1 
ATOM 3279 C CZ  . PHE B 2 209 ? 97.257  117.264 64.834  1.00 75.64  ? 199 PHE B CZ  1 
ATOM 3280 N N   . VAL B 2 210 ? 91.883  116.631 67.177  1.00 69.88  ? 200 VAL B N   1 
ATOM 3281 C CA  . VAL B 2 210 ? 91.611  117.922 67.797  1.00 70.89  ? 200 VAL B CA  1 
ATOM 3282 C C   . VAL B 2 210 ? 92.634  118.164 68.896  1.00 72.22  ? 200 VAL B C   1 
ATOM 3283 O O   . VAL B 2 210 ? 93.109  117.227 69.547  1.00 71.26  ? 200 VAL B O   1 
ATOM 3284 C CB  . VAL B 2 210 ? 90.174  118.003 68.356  1.00 73.38  ? 200 VAL B CB  1 
ATOM 3285 C CG1 . VAL B 2 210 ? 89.163  117.975 67.222  1.00 76.60  ? 200 VAL B CG1 1 
ATOM 3286 C CG2 . VAL B 2 210 ? 89.917  116.864 69.331  1.00 78.83  ? 200 VAL B CG2 1 
ATOM 3287 N N   . SER B 2 211 ? 92.982  119.433 69.096  1.00 78.00  ? 201 SER B N   1 
ATOM 3288 C CA  . SER B 2 211 ? 93.897  119.827 70.157  1.00 73.71  ? 201 SER B CA  1 
ATOM 3289 C C   . SER B 2 211 ? 93.338  121.033 70.898  1.00 77.37  ? 201 SER B C   1 
ATOM 3290 O O   . SER B 2 211 ? 92.758  121.935 70.288  1.00 79.50  ? 201 SER B O   1 
ATOM 3291 C CB  . SER B 2 211 ? 95.286  120.155 69.596  1.00 71.06  ? 201 SER B CB  1 
ATOM 3292 O OG  . SER B 2 211 ? 95.220  121.223 68.667  1.00 72.39  ? 201 SER B OG  1 
ATOM 3293 N N   . GLY B 2 212 ? 93.524  121.041 72.216  1.00 75.32  ? 202 GLY B N   1 
ATOM 3294 C CA  . GLY B 2 212 ? 93.132  122.155 73.064  1.00 74.67  ? 202 GLY B CA  1 
ATOM 3295 C C   . GLY B 2 212 ? 94.358  122.817 73.671  1.00 74.48  ? 202 GLY B C   1 
ATOM 3296 O O   . GLY B 2 212 ? 95.264  122.137 74.156  1.00 71.48  ? 202 GLY B O   1 
ATOM 3297 N N   . ALA B 2 213 ? 94.372  124.145 73.637  1.00 79.09  ? 203 ALA B N   1 
ATOM 3298 C CA  . ALA B 2 213 ? 95.516  124.920 74.096  1.00 81.20  ? 203 ALA B CA  1 
ATOM 3299 C C   . ALA B 2 213 ? 95.110  125.835 75.249  1.00 77.97  ? 203 ALA B C   1 
ATOM 3300 O O   . ALA B 2 213 ? 93.963  125.837 75.702  1.00 78.75  ? 203 ALA B O   1 
ATOM 3301 C CB  . ALA B 2 213 ? 96.124  125.725 72.944  1.00 80.61  ? 203 ALA B CB  1 
ATOM 3302 N N   . CYS B 2 214 ? 96.076  126.624 75.719  1.00 81.67  ? 204 CYS B N   1 
ATOM 3303 C CA  . CYS B 2 214 ? 95.862  127.576 76.801  1.00 85.03  ? 204 CYS B CA  1 
ATOM 3304 C C   . CYS B 2 214 ? 95.312  128.911 76.322  1.00 84.32  ? 204 CYS B C   1 
ATOM 3305 O O   . CYS B 2 214 ? 95.061  129.794 77.149  1.00 87.20  ? 204 CYS B O   1 
ATOM 3306 C CB  . CYS B 2 214 ? 97.169  127.809 77.566  1.00 90.38  ? 204 CYS B CB  1 
ATOM 3307 S SG  . CYS B 2 214 ? 97.811  126.351 78.417  1.00 95.85  ? 204 CYS B SG  1 
ATOM 3308 N N   . ASP B 2 215 ? 95.119  129.082 75.017  1.00 90.55  ? 205 ASP B N   1 
ATOM 3309 C CA  . ASP B 2 215 ? 94.389  130.219 74.475  1.00 93.77  ? 205 ASP B CA  1 
ATOM 3310 C C   . ASP B 2 215 ? 92.879  130.007 74.487  1.00 96.60  ? 205 ASP B C   1 
ATOM 3311 O O   . ASP B 2 215 ? 92.157  130.732 73.791  1.00 97.66  ? 205 ASP B O   1 
ATOM 3312 C CB  . ASP B 2 215 ? 94.877  130.528 73.057  1.00 91.64  ? 205 ASP B CB  1 
ATOM 3313 C CG  . ASP B 2 215 ? 94.892  129.303 72.164  1.00 95.39  ? 205 ASP B CG  1 
ATOM 3314 O OD1 . ASP B 2 215 ? 94.302  128.272 72.548  1.00 97.65  ? 205 ASP B OD1 1 
ATOM 3315 O OD2 . ASP B 2 215 ? 95.506  129.368 71.078  1.00 94.96  ? 205 ASP B OD2 1 
ATOM 3316 N N   . ALA B 2 216 ? 92.407  129.020 75.253  1.00 81.16  ? 206 ALA B N   1 
ATOM 3317 C CA  . ALA B 2 216 ? 90.981  128.740 75.424  1.00 79.40  ? 206 ALA B CA  1 
ATOM 3318 C C   . ALA B 2 216 ? 90.308  128.371 74.106  1.00 79.53  ? 206 ALA B C   1 
ATOM 3319 O O   . ALA B 2 216 ? 89.109  128.599 73.924  1.00 77.34  ? 206 ALA B O   1 
ATOM 3320 C CB  . ALA B 2 216 ? 90.256  129.916 76.085  1.00 81.13  ? 206 ALA B CB  1 
ATOM 3321 N N   . SER B 2 217 ? 91.068  127.796 73.176  1.00 85.99  ? 207 SER B N   1 
ATOM 3322 C CA  . SER B 2 217 ? 90.547  127.437 71.867  1.00 88.18  ? 207 SER B CA  1 
ATOM 3323 C C   . SER B 2 217 ? 90.933  126.005 71.528  1.00 86.29  ? 207 SER B C   1 
ATOM 3324 O O   . SER B 2 217 ? 91.979  125.507 71.953  1.00 86.71  ? 207 SER B O   1 
ATOM 3325 C CB  . SER B 2 217 ? 91.064  128.384 70.775  1.00 87.87  ? 207 SER B CB  1 
ATOM 3326 O OG  . SER B 2 217 ? 92.470  128.284 70.638  1.00 88.22  ? 207 SER B OG  1 
ATOM 3327 N N   . ALA B 2 218 ? 90.071  125.348 70.756  1.00 77.77  ? 208 ALA B N   1 
ATOM 3328 C CA  . ALA B 2 218 ? 90.298  123.991 70.278  1.00 75.75  ? 208 ALA B CA  1 
ATOM 3329 C C   . ALA B 2 218 ? 90.342  124.004 68.758  1.00 79.30  ? 208 ALA B C   1 
ATOM 3330 O O   . ALA B 2 218 ? 89.434  124.542 68.115  1.00 84.88  ? 208 ALA B O   1 
ATOM 3331 C CB  . ALA B 2 218 ? 89.207  123.039 70.773  1.00 86.11  ? 208 ALA B CB  1 
ATOM 3332 N N   . LYS B 2 219 ? 91.391  123.421 68.185  1.00 86.44  ? 209 LYS B N   1 
ATOM 3333 C CA  . LYS B 2 219 ? 91.566  123.380 66.740  1.00 88.75  ? 209 LYS B CA  1 
ATOM 3334 C C   . LYS B 2 219 ? 91.476  121.952 66.218  1.00 91.36  ? 209 LYS B C   1 
ATOM 3335 O O   . LYS B 2 219 ? 92.021  121.021 66.819  1.00 93.57  ? 209 LYS B O   1 
ATOM 3336 C CB  . LYS B 2 219 ? 92.903  124.001 66.329  1.00 84.70  ? 209 LYS B CB  1 
ATOM 3337 C CG  . LYS B 2 219 ? 92.961  125.501 66.537  1.00 87.05  ? 209 LYS B CG  1 
ATOM 3338 C CD  . LYS B 2 219 ? 94.300  126.077 66.116  1.00 87.37  ? 209 LYS B CD  1 
ATOM 3339 C CE  . LYS B 2 219 ? 94.340  127.573 66.364  1.00 84.06  ? 209 LYS B CE  1 
ATOM 3340 N NZ  . LYS B 2 219 ? 93.254  128.279 65.628  1.00 84.23  ? 209 LYS B NZ  1 
ATOM 3341 N N   . LEU B 2 220 ? 90.783  121.793 65.092  1.00 100.93 ? 210 LEU B N   1 
ATOM 3342 C CA  . LEU B 2 220 ? 90.652  120.515 64.404  1.00 96.69  ? 210 LEU B CA  1 
ATOM 3343 C C   . LEU B 2 220 ? 91.648  120.469 63.253  1.00 94.74  ? 210 LEU B C   1 
ATOM 3344 O O   . LEU B 2 220 ? 91.641  121.350 62.386  1.00 98.38  ? 210 LEU B O   1 
ATOM 3345 C CB  . LEU B 2 220 ? 89.227  120.314 63.889  1.00 97.79  ? 210 LEU B CB  1 
ATOM 3346 C CG  . LEU B 2 220 ? 89.013  119.148 62.921  1.00 97.93  ? 210 LEU B CG  1 
ATOM 3347 C CD1 . LEU B 2 220 ? 89.343  117.817 63.579  1.00 98.08  ? 210 LEU B CD1 1 
ATOM 3348 C CD2 . LEU B 2 220 ? 87.590  119.147 62.381  1.00 100.50 ? 210 LEU B CD2 1 
ATOM 3349 N N   . TRP B 2 221 ? 92.502  119.451 63.247  1.00 80.82  ? 211 TRP B N   1 
ATOM 3350 C CA  . TRP B 2 221 ? 93.587  119.342 62.284  1.00 86.30  ? 211 TRP B CA  1 
ATOM 3351 C C   . TRP B 2 221 ? 93.351  118.160 61.353  1.00 91.45  ? 211 TRP B C   1 
ATOM 3352 O O   . TRP B 2 221 ? 92.855  117.111 61.777  1.00 92.89  ? 211 TRP B O   1 
ATOM 3353 C CB  . TRP B 2 221 ? 94.935  119.176 62.988  1.00 81.96  ? 211 TRP B CB  1 
ATOM 3354 C CG  . TRP B 2 221 ? 95.216  120.215 64.021  1.00 83.63  ? 211 TRP B CG  1 
ATOM 3355 C CD1 . TRP B 2 221 ? 94.865  120.177 65.339  1.00 83.15  ? 211 TRP B CD1 1 
ATOM 3356 C CD2 . TRP B 2 221 ? 95.911  121.451 63.826  1.00 87.98  ? 211 TRP B CD2 1 
ATOM 3357 N NE1 . TRP B 2 221 ? 95.299  121.312 65.977  1.00 87.12  ? 211 TRP B NE1 1 
ATOM 3358 C CE2 . TRP B 2 221 ? 95.944  122.112 65.071  1.00 89.35  ? 211 TRP B CE2 1 
ATOM 3359 C CE3 . TRP B 2 221 ? 96.506  122.065 62.720  1.00 83.63  ? 211 TRP B CE3 1 
ATOM 3360 C CZ2 . TRP B 2 221 ? 96.550  123.353 65.240  1.00 87.52  ? 211 TRP B CZ2 1 
ATOM 3361 C CZ3 . TRP B 2 221 ? 97.110  123.295 62.890  1.00 81.48  ? 211 TRP B CZ3 1 
ATOM 3362 C CH2 . TRP B 2 221 ? 97.126  123.928 64.141  1.00 83.76  ? 211 TRP B CH2 1 
ATOM 3363 N N   . ASP B 2 222 ? 93.708  118.338 60.085  1.00 100.32 ? 212 ASP B N   1 
ATOM 3364 C CA  . ASP B 2 222 ? 93.730  117.246 59.122  1.00 97.02  ? 212 ASP B CA  1 
ATOM 3365 C C   . ASP B 2 222 ? 95.118  116.617 59.142  1.00 93.91  ? 212 ASP B C   1 
ATOM 3366 O O   . ASP B 2 222 ? 96.120  117.309 58.929  1.00 94.04  ? 212 ASP B O   1 
ATOM 3367 C CB  . ASP B 2 222 ? 93.373  117.746 57.722  1.00 98.33  ? 212 ASP B CB  1 
ATOM 3368 C CG  . ASP B 2 222 ? 92.989  116.621 56.776  1.00 99.88  ? 212 ASP B CG  1 
ATOM 3369 O OD1 . ASP B 2 222 ? 93.632  115.551 56.817  1.00 99.59  ? 212 ASP B OD1 1 
ATOM 3370 O OD2 . ASP B 2 222 ? 92.038  116.807 55.988  1.00 101.57 ? 212 ASP B OD2 1 
ATOM 3371 N N   . VAL B 2 223 ? 95.176  115.311 59.405  1.00 91.67  ? 213 VAL B N   1 
ATOM 3372 C CA  . VAL B 2 223 ? 96.465  114.641 59.552  1.00 92.86  ? 213 VAL B CA  1 
ATOM 3373 C C   . VAL B 2 223 ? 97.215  114.628 58.226  1.00 94.62  ? 213 VAL B C   1 
ATOM 3374 O O   . VAL B 2 223 ? 98.402  114.970 58.162  1.00 97.12  ? 213 VAL B O   1 
ATOM 3375 C CB  . VAL B 2 223 ? 96.268  113.218 60.104  1.00 93.65  ? 213 VAL B CB  1 
ATOM 3376 C CG1 . VAL B 2 223 ? 97.602  112.504 60.226  1.00 90.63  ? 213 VAL B CG1 1 
ATOM 3377 C CG2 . VAL B 2 223 ? 95.564  113.266 61.450  1.00 91.61  ? 213 VAL B CG2 1 
ATOM 3378 N N   . ARG B 2 224 ? 96.538  114.229 57.148  1.00 105.25 ? 214 ARG B N   1 
ATOM 3379 C CA  . ARG B 2 224 ? 97.216  114.095 55.862  1.00 106.82 ? 214 ARG B CA  1 
ATOM 3380 C C   . ARG B 2 224 ? 97.552  115.457 55.266  1.00 108.01 ? 214 ARG B C   1 
ATOM 3381 O O   . ARG B 2 224 ? 98.674  115.679 54.797  1.00 107.53 ? 214 ARG B O   1 
ATOM 3382 C CB  . ARG B 2 224 ? 96.361  113.268 54.902  1.00 107.90 ? 214 ARG B CB  1 
ATOM 3383 C CG  . ARG B 2 224 ? 96.154  111.838 55.373  1.00 108.58 ? 214 ARG B CG  1 
ATOM 3384 C CD  . ARG B 2 224 ? 97.492  111.162 55.631  1.00 109.30 ? 214 ARG B CD  1 
ATOM 3385 N NE  . ARG B 2 224 ? 97.341  109.802 56.133  1.00 111.17 ? 214 ARG B NE  1 
ATOM 3386 C CZ  . ARG B 2 224 ? 98.350  109.021 56.492  1.00 110.94 ? 214 ARG B CZ  1 
ATOM 3387 N NH1 . ARG B 2 224 ? 99.605  109.435 56.419  1.00 109.78 ? 214 ARG B NH1 1 
ATOM 3388 N NH2 . ARG B 2 224 ? 98.095  107.794 56.939  1.00 107.44 ? 214 ARG B NH2 1 
ATOM 3389 N N   . GLU B 2 225 ? 96.592  116.386 55.272  1.00 116.98 ? 215 GLU B N   1 
ATOM 3390 C CA  . GLU B 2 225 ? 96.834  117.683 54.647  1.00 117.96 ? 215 GLU B CA  1 
ATOM 3391 C C   . GLU B 2 225 ? 97.746  118.550 55.506  1.00 117.94 ? 215 GLU B C   1 
ATOM 3392 O O   . GLU B 2 225 ? 98.596  119.277 54.979  1.00 115.42 ? 215 GLU B O   1 
ATOM 3393 C CB  . GLU B 2 225 ? 95.507  118.394 54.379  1.00 117.79 ? 215 GLU B CB  1 
ATOM 3394 C CG  . GLU B 2 225 ? 95.637  119.641 53.517  1.00 119.48 ? 215 GLU B CG  1 
ATOM 3395 C CD  . GLU B 2 225 ? 96.054  119.332 52.091  1.00 120.38 ? 215 GLU B CD  1 
ATOM 3396 O OE1 . GLU B 2 225 ? 95.798  118.202 51.624  1.00 120.33 ? 215 GLU B OE1 1 
ATOM 3397 O OE2 . GLU B 2 225 ? 96.640  120.219 51.437  1.00 119.02 ? 215 GLU B OE2 1 
ATOM 3398 N N   . GLY B 2 226 ? 97.589  118.488 56.825  1.00 109.09 ? 216 GLY B N   1 
ATOM 3399 C CA  . GLY B 2 226 ? 98.485  119.185 57.723  1.00 107.36 ? 216 GLY B CA  1 
ATOM 3400 C C   . GLY B 2 226 ? 98.124  120.610 58.072  1.00 105.52 ? 216 GLY B C   1 
ATOM 3401 O O   . GLY B 2 226 ? 98.995  121.350 58.544  1.00 104.06 ? 216 GLY B O   1 
ATOM 3402 N N   . MET B 2 227 ? 96.880  121.024 57.864  1.00 111.67 ? 217 MET B N   1 
ATOM 3403 C CA  . MET B 2 227 ? 96.446  122.373 58.190  1.00 111.73 ? 217 MET B CA  1 
ATOM 3404 C C   . MET B 2 227 ? 95.293  122.322 59.184  1.00 111.69 ? 217 MET B C   1 
ATOM 3405 O O   . MET B 2 227 ? 94.672  121.279 59.403  1.00 112.25 ? 217 MET B O   1 
ATOM 3406 C CB  . MET B 2 227 ? 96.040  123.140 56.924  1.00 111.64 ? 217 MET B CB  1 
ATOM 3407 C CG  . MET B 2 227 ? 95.218  122.328 55.933  1.00 113.30 ? 217 MET B CG  1 
ATOM 3408 S SD  . MET B 2 227 ? 93.470  122.203 56.360  1.00 120.20 ? 217 MET B SD  1 
ATOM 3409 C CE  . MET B 2 227 ? 92.936  123.889 56.074  1.00 112.40 ? 217 MET B CE  1 
ATOM 3410 N N   . CYS B 2 228 ? 95.010  123.472 59.794  1.00 105.79 ? 218 CYS B N   1 
ATOM 3411 C CA  . CYS B 2 228 ? 93.906  123.575 60.738  1.00 102.57 ? 218 CYS B CA  1 
ATOM 3412 C C   . CYS B 2 228 ? 92.607  123.748 59.964  1.00 103.98 ? 218 CYS B C   1 
ATOM 3413 O O   . CYS B 2 228 ? 92.464  124.693 59.180  1.00 107.74 ? 218 CYS B O   1 
ATOM 3414 C CB  . CYS B 2 228 ? 94.125  124.744 61.696  1.00 105.58 ? 218 CYS B CB  1 
ATOM 3415 S SG  . CYS B 2 228 ? 92.773  125.007 62.866  1.00 107.71 ? 218 CYS B SG  1 
ATOM 3416 N N   . ARG B 2 229 ? 91.657  122.841 60.189  1.00 105.84 ? 219 ARG B N   1 
ATOM 3417 C CA  . ARG B 2 229 ? 90.374  122.925 59.501  1.00 109.23 ? 219 ARG B CA  1 
ATOM 3418 C C   . ARG B 2 229 ? 89.406  123.857 60.222  1.00 109.18 ? 219 ARG B C   1 
ATOM 3419 O O   . ARG B 2 229 ? 88.790  124.726 59.594  1.00 107.83 ? 219 ARG B O   1 
ATOM 3420 C CB  . ARG B 2 229 ? 89.775  121.527 59.348  1.00 108.04 ? 219 ARG B CB  1 
ATOM 3421 C CG  . ARG B 2 229 ? 90.656  120.581 58.546  1.00 106.48 ? 219 ARG B CG  1 
ATOM 3422 C CD  . ARG B 2 229 ? 89.986  119.237 58.328  1.00 105.79 ? 219 ARG B CD  1 
ATOM 3423 N NE  . ARG B 2 229 ? 88.705  119.374 57.648  1.00 109.57 ? 219 ARG B NE  1 
ATOM 3424 C CZ  . ARG B 2 229 ? 88.557  119.411 56.331  1.00 110.47 ? 219 ARG B CZ  1 
ATOM 3425 N NH1 . ARG B 2 229 ? 89.596  119.328 55.516  1.00 110.40 ? 219 ARG B NH1 1 
ATOM 3426 N NH2 . ARG B 2 229 ? 87.336  119.535 55.818  1.00 110.16 ? 219 ARG B NH2 1 
ATOM 3427 N N   . GLN B 2 230 ? 89.253  123.692 61.535  1.00 112.39 ? 220 GLN B N   1 
ATOM 3428 C CA  . GLN B 2 230 ? 88.295  124.477 62.301  1.00 111.47 ? 220 GLN B CA  1 
ATOM 3429 C C   . GLN B 2 230 ? 88.895  124.849 63.648  1.00 110.12 ? 220 GLN B C   1 
ATOM 3430 O O   . GLN B 2 230 ? 89.748  124.138 64.185  1.00 111.00 ? 220 GLN B O   1 
ATOM 3431 C CB  . GLN B 2 230 ? 86.978  123.712 62.510  1.00 111.77 ? 220 GLN B CB  1 
ATOM 3432 C CG  . GLN B 2 230 ? 86.303  123.259 61.222  1.00 115.36 ? 220 GLN B CG  1 
ATOM 3433 C CD  . GLN B 2 230 ? 84.991  122.539 61.463  1.00 114.36 ? 220 GLN B CD  1 
ATOM 3434 O OE1 . GLN B 2 230 ? 84.521  121.783 60.612  1.00 113.49 ? 220 GLN B OE1 1 
ATOM 3435 N NE2 . GLN B 2 230 ? 84.392  122.771 62.624  1.00 113.23 ? 220 GLN B NE2 1 
ATOM 3436 N N   . THR B 2 231 ? 88.436  125.976 64.190  1.00 101.98 ? 221 THR B N   1 
ATOM 3437 C CA  . THR B 2 231 ? 88.839  126.454 65.506  1.00 100.48 ? 221 THR B CA  1 
ATOM 3438 C C   . THR B 2 231 ? 87.602  126.631 66.375  1.00 103.28 ? 221 THR B C   1 
ATOM 3439 O O   . THR B 2 231 ? 86.621  127.246 65.945  1.00 104.50 ? 221 THR B O   1 
ATOM 3440 C CB  . THR B 2 231 ? 89.611  127.773 65.406  1.00 100.98 ? 221 THR B CB  1 
ATOM 3441 O OG1 . THR B 2 231 ? 90.766  127.591 64.578  1.00 104.52 ? 221 THR B OG1 1 
ATOM 3442 C CG2 . THR B 2 231 ? 90.053  128.239 66.786  1.00 97.90  ? 221 THR B CG2 1 
ATOM 3443 N N   . PHE B 2 232 ? 87.653  126.099 67.595  1.00 98.60  ? 222 PHE B N   1 
ATOM 3444 C CA  . PHE B 2 232 ? 86.529  126.140 68.524  1.00 95.43  ? 222 PHE B CA  1 
ATOM 3445 C C   . PHE B 2 232 ? 86.938  126.948 69.747  1.00 94.42  ? 222 PHE B C   1 
ATOM 3446 O O   . PHE B 2 232 ? 87.913  126.605 70.422  1.00 94.32  ? 222 PHE B O   1 
ATOM 3447 C CB  . PHE B 2 232 ? 86.101  124.729 68.932  1.00 93.10  ? 222 PHE B CB  1 
ATOM 3448 C CG  . PHE B 2 232 ? 85.815  123.821 67.771  1.00 92.61  ? 222 PHE B CG  1 
ATOM 3449 C CD1 . PHE B 2 232 ? 84.555  123.779 67.202  1.00 95.41  ? 222 PHE B CD1 1 
ATOM 3450 C CD2 . PHE B 2 232 ? 86.808  123.007 67.251  1.00 93.28  ? 222 PHE B CD2 1 
ATOM 3451 C CE1 . PHE B 2 232 ? 84.291  122.943 66.136  1.00 99.90  ? 222 PHE B CE1 1 
ATOM 3452 C CE2 . PHE B 2 232 ? 86.549  122.169 66.185  1.00 94.43  ? 222 PHE B CE2 1 
ATOM 3453 C CZ  . PHE B 2 232 ? 85.289  122.137 65.627  1.00 98.26  ? 222 PHE B CZ  1 
ATOM 3454 N N   . THR B 2 233 ? 86.183  128.004 70.037  1.00 96.47  ? 223 THR B N   1 
ATOM 3455 C CA  . THR B 2 233 ? 86.403  128.867 71.188  1.00 97.88  ? 223 THR B CA  1 
ATOM 3456 C C   . THR B 2 233 ? 85.166  128.871 72.078  1.00 96.44  ? 223 THR B C   1 
ATOM 3457 O O   . THR B 2 233 ? 84.111  128.341 71.721  1.00 98.10  ? 223 THR B O   1 
ATOM 3458 C CB  . THR B 2 233 ? 86.747  130.298 70.754  1.00 98.09  ? 223 THR B CB  1 
ATOM 3459 O OG1 . THR B 2 233 ? 85.669  130.838 69.980  1.00 96.79  ? 223 THR B OG1 1 
ATOM 3460 C CG2 . THR B 2 233 ? 88.021  130.311 69.922  1.00 98.09  ? 223 THR B CG2 1 
ATOM 3461 N N   . GLY B 2 234 ? 85.307  129.479 73.254  1.00 86.22  ? 224 GLY B N   1 
ATOM 3462 C CA  . GLY B 2 234 ? 84.211  129.523 74.202  1.00 87.13  ? 224 GLY B CA  1 
ATOM 3463 C C   . GLY B 2 234 ? 84.623  129.361 75.650  1.00 86.86  ? 224 GLY B C   1 
ATOM 3464 O O   . GLY B 2 234 ? 83.924  129.832 76.552  1.00 88.79  ? 224 GLY B O   1 
ATOM 3465 N N   . HIS B 2 235 ? 85.752  128.702 75.891  1.00 81.62  ? 225 HIS B N   1 
ATOM 3466 C CA  . HIS B 2 235 ? 86.279  128.601 77.243  1.00 81.54  ? 225 HIS B CA  1 
ATOM 3467 C C   . HIS B 2 235 ? 86.847  129.937 77.709  1.00 86.66  ? 225 HIS B C   1 
ATOM 3468 O O   . HIS B 2 235 ? 87.246  130.785 76.907  1.00 88.51  ? 225 HIS B O   1 
ATOM 3469 C CB  . HIS B 2 235 ? 87.366  127.529 77.312  1.00 82.27  ? 225 HIS B CB  1 
ATOM 3470 C CG  . HIS B 2 235 ? 86.836  126.138 77.467  1.00 84.41  ? 225 HIS B CG  1 
ATOM 3471 N ND1 . HIS B 2 235 ? 86.442  125.624 78.683  1.00 77.52  ? 225 HIS B ND1 1 
ATOM 3472 C CD2 . HIS B 2 235 ? 86.642  125.151 76.561  1.00 89.18  ? 225 HIS B CD2 1 
ATOM 3473 C CE1 . HIS B 2 235 ? 86.028  124.380 78.519  1.00 82.07  ? 225 HIS B CE1 1 
ATOM 3474 N NE2 . HIS B 2 235 ? 86.137  124.069 77.240  1.00 83.69  ? 225 HIS B NE2 1 
ATOM 3475 N N   . GLU B 2 236 ? 86.871  130.122 79.030  1.00 91.29  ? 226 GLU B N   1 
ATOM 3476 C CA  . GLU B 2 236 ? 87.368  131.352 79.630  1.00 91.44  ? 226 GLU B CA  1 
ATOM 3477 C C   . GLU B 2 236 ? 88.766  131.206 80.215  1.00 88.30  ? 226 GLU B C   1 
ATOM 3478 O O   . GLU B 2 236 ? 89.347  132.210 80.643  1.00 88.92  ? 226 GLU B O   1 
ATOM 3479 C CB  . GLU B 2 236 ? 86.409  131.838 80.725  1.00 89.59  ? 226 GLU B CB  1 
ATOM 3480 C CG  . GLU B 2 236 ? 84.991  132.096 80.243  1.00 90.76  ? 226 GLU B CG  1 
ATOM 3481 C CD  . GLU B 2 236 ? 84.066  132.529 81.364  1.00 94.11  ? 226 GLU B CD  1 
ATOM 3482 O OE1 . GLU B 2 236 ? 84.528  132.606 82.521  1.00 93.52  ? 226 GLU B OE1 1 
ATOM 3483 O OE2 . GLU B 2 236 ? 82.877  132.796 81.086  1.00 95.48  ? 226 GLU B OE2 1 
ATOM 3484 N N   . SER B 2 237 ? 89.316  129.994 80.248  1.00 78.31  ? 227 SER B N   1 
ATOM 3485 C CA  . SER B 2 237 ? 90.653  129.770 80.775  1.00 74.30  ? 227 SER B CA  1 
ATOM 3486 C C   . SER B 2 237 ? 91.313  128.656 79.972  1.00 77.19  ? 227 SER B C   1 
ATOM 3487 O O   . SER B 2 237 ? 90.750  128.146 78.998  1.00 85.98  ? 227 SER B O   1 
ATOM 3488 C CB  . SER B 2 237 ? 90.611  129.435 82.270  1.00 81.50  ? 227 SER B CB  1 
ATOM 3489 O OG  . SER B 2 237 ? 89.899  128.233 82.506  1.00 84.07  ? 227 SER B OG  1 
ATOM 3490 N N   . ASP B 2 238 ? 92.524  128.290 80.386  1.00 76.89  ? 228 ASP B N   1 
ATOM 3491 C CA  . ASP B 2 238 ? 93.305  127.289 79.671  1.00 81.47  ? 228 ASP B CA  1 
ATOM 3492 C C   . ASP B 2 238 ? 92.562  125.959 79.594  1.00 82.59  ? 228 ASP B C   1 
ATOM 3493 O O   . ASP B 2 238 ? 92.003  125.482 80.585  1.00 89.76  ? 228 ASP B O   1 
ATOM 3494 C CB  . ASP B 2 238 ? 94.657  127.112 80.358  1.00 79.28  ? 228 ASP B CB  1 
ATOM 3495 C CG  . ASP B 2 238 ? 95.184  128.414 80.931  1.00 86.76  ? 228 ASP B CG  1 
ATOM 3496 O OD1 . ASP B 2 238 ? 94.550  129.463 80.692  1.00 89.29  ? 228 ASP B OD1 1 
ATOM 3497 O OD2 . ASP B 2 238 ? 96.223  128.395 81.622  1.00 88.07  ? 228 ASP B OD2 1 
ATOM 3498 N N   . ILE B 2 239 ? 92.579  125.352 78.410  1.00 70.77  ? 229 ILE B N   1 
ATOM 3499 C CA  . ILE B 2 239 ? 92.040  124.009 78.219  1.00 66.72  ? 229 ILE B CA  1 
ATOM 3500 C C   . ILE B 2 239 ? 93.099  122.984 78.598  1.00 64.48  ? 229 ILE B C   1 
ATOM 3501 O O   . ILE B 2 239 ? 94.228  123.026 78.095  1.00 63.64  ? 229 ILE B O   1 
ATOM 3502 C CB  . ILE B 2 239 ? 91.570  123.813 76.769  1.00 60.90  ? 229 ILE B CB  1 
ATOM 3503 C CG1 . ILE B 2 239 ? 90.445  124.795 76.439  1.00 66.28  ? 229 ILE B CG1 1 
ATOM 3504 C CG2 . ILE B 2 239 ? 91.122  122.380 76.544  1.00 62.02  ? 229 ILE B CG2 1 
ATOM 3505 C CD1 . ILE B 2 239 ? 89.905  124.658 75.034  1.00 68.08  ? 229 ILE B CD1 1 
ATOM 3506 N N   . ASN B 2 240 ? 92.735  122.053 79.484  1.00 66.80  ? 230 ASN B N   1 
ATOM 3507 C CA  . ASN B 2 240 ? 93.662  121.046 79.981  1.00 64.94  ? 230 ASN B CA  1 
ATOM 3508 C C   . ASN B 2 240 ? 93.430  119.647 79.427  1.00 71.53  ? 230 ASN B C   1 
ATOM 3509 O O   . ASN B 2 240 ? 94.355  118.830 79.466  1.00 72.57  ? 230 ASN B O   1 
ATOM 3510 C CB  . ASN B 2 240 ? 93.597  120.974 81.513  1.00 63.21  ? 230 ASN B CB  1 
ATOM 3511 C CG  . ASN B 2 240 ? 93.953  122.288 82.175  1.00 70.32  ? 230 ASN B CG  1 
ATOM 3512 O OD1 . ASN B 2 240 ? 94.809  123.030 81.693  1.00 80.35  ? 230 ASN B OD1 1 
ATOM 3513 N ND2 . ASN B 2 240 ? 93.296  122.582 83.290  1.00 63.62  ? 230 ASN B ND2 1 
ATOM 3514 N N   . ALA B 2 241 ? 92.234  119.345 78.925  1.00 63.21  ? 231 ALA B N   1 
ATOM 3515 C CA  . ALA B 2 241 ? 91.909  117.989 78.511  1.00 56.20  ? 231 ALA B CA  1 
ATOM 3516 C C   . ALA B 2 241 ? 90.997  118.022 77.295  1.00 55.70  ? 231 ALA B C   1 
ATOM 3517 O O   . ALA B 2 241 ? 90.262  118.989 77.080  1.00 60.98  ? 231 ALA B O   1 
ATOM 3518 C CB  . ALA B 2 241 ? 91.238  117.206 79.642  1.00 59.00  ? 231 ALA B CB  1 
ATOM 3519 N N   . ILE B 2 242 ? 91.063  116.959 76.498  1.00 56.89  ? 232 ILE B N   1 
ATOM 3520 C CA  . ILE B 2 242 ? 90.266  116.859 75.280  1.00 62.44  ? 232 ILE B CA  1 
ATOM 3521 C C   . ILE B 2 242 ? 90.126  115.383 74.925  1.00 68.99  ? 232 ILE B C   1 
ATOM 3522 O O   . ILE B 2 242 ? 91.032  114.582 75.172  1.00 70.57  ? 232 ILE B O   1 
ATOM 3523 C CB  . ILE B 2 242 ? 90.899  117.684 74.133  1.00 61.78  ? 232 ILE B CB  1 
ATOM 3524 C CG1 . ILE B 2 242 ? 89.862  118.027 73.068  1.00 63.74  ? 232 ILE B CG1 1 
ATOM 3525 C CG2 . ILE B 2 242 ? 92.052  116.937 73.499  1.00 62.09  ? 232 ILE B CG2 1 
ATOM 3526 C CD1 . ILE B 2 242 ? 90.327  119.113 72.122  1.00 61.91  ? 232 ILE B CD1 1 
ATOM 3527 N N   . CYS B 2 243 ? 88.964  115.021 74.383  1.00 68.43  ? 233 CYS B N   1 
ATOM 3528 C CA  . CYS B 2 243 ? 88.670  113.627 74.072  1.00 61.41  ? 233 CYS B CA  1 
ATOM 3529 C C   . CYS B 2 243 ? 87.633  113.573 72.962  1.00 70.21  ? 233 CYS B C   1 
ATOM 3530 O O   . CYS B 2 243 ? 86.610  114.257 73.037  1.00 73.40  ? 233 CYS B O   1 
ATOM 3531 C CB  . CYS B 2 243 ? 88.163  112.873 75.306  1.00 65.27  ? 233 CYS B CB  1 
ATOM 3532 S SG  . CYS B 2 243 ? 87.750  111.145 74.985  1.00 88.80  ? 233 CYS B SG  1 
ATOM 3533 N N   . PHE B 2 244 ? 87.896  112.753 71.948  1.00 78.87  ? 234 PHE B N   1 
ATOM 3534 C CA  . PHE B 2 244 ? 86.958  112.588 70.846  1.00 77.00  ? 234 PHE B CA  1 
ATOM 3535 C C   . PHE B 2 244 ? 85.733  111.791 71.275  1.00 75.22  ? 234 PHE B C   1 
ATOM 3536 O O   . PHE B 2 244 ? 85.820  110.871 72.092  1.00 74.90  ? 234 PHE B O   1 
ATOM 3537 C CB  . PHE B 2 244 ? 87.637  111.889 69.668  1.00 75.30  ? 234 PHE B CB  1 
ATOM 3538 C CG  . PHE B 2 244 ? 87.893  112.787 68.490  1.00 71.46  ? 234 PHE B CG  1 
ATOM 3539 C CD1 . PHE B 2 244 ? 86.873  113.096 67.606  1.00 75.92  ? 234 PHE B CD1 1 
ATOM 3540 C CD2 . PHE B 2 244 ? 89.153  113.309 68.259  1.00 69.07  ? 234 PHE B CD2 1 
ATOM 3541 C CE1 . PHE B 2 244 ? 87.101  113.917 66.520  1.00 79.14  ? 234 PHE B CE1 1 
ATOM 3542 C CE2 . PHE B 2 244 ? 89.389  114.130 67.172  1.00 74.27  ? 234 PHE B CE2 1 
ATOM 3543 C CZ  . PHE B 2 244 ? 88.361  114.435 66.302  1.00 73.73  ? 234 PHE B CZ  1 
ATOM 3544 N N   . PHE B 2 245 ? 84.582  112.159 70.716  1.00 79.09  ? 235 PHE B N   1 
ATOM 3545 C CA  . PHE B 2 245 ? 83.386  111.348 70.859  1.00 78.08  ? 235 PHE B CA  1 
ATOM 3546 C C   . PHE B 2 245 ? 83.573  110.030 70.107  1.00 84.94  ? 235 PHE B C   1 
ATOM 3547 O O   . PHE B 2 245 ? 84.287  109.978 69.102  1.00 93.78  ? 235 PHE B O   1 
ATOM 3548 C CB  . PHE B 2 245 ? 82.171  112.103 70.317  1.00 85.00  ? 235 PHE B CB  1 
ATOM 3549 C CG  . PHE B 2 245 ? 80.856  111.663 70.903  1.00 80.03  ? 235 PHE B CG  1 
ATOM 3550 C CD1 . PHE B 2 245 ? 80.493  112.036 72.187  1.00 79.90  ? 235 PHE B CD1 1 
ATOM 3551 C CD2 . PHE B 2 245 ? 79.973  110.898 70.160  1.00 77.64  ? 235 PHE B CD2 1 
ATOM 3552 C CE1 . PHE B 2 245 ? 79.282  111.639 72.722  1.00 80.28  ? 235 PHE B CE1 1 
ATOM 3553 C CE2 . PHE B 2 245 ? 78.762  110.499 70.690  1.00 78.87  ? 235 PHE B CE2 1 
ATOM 3554 C CZ  . PHE B 2 245 ? 78.416  110.870 71.972  1.00 80.49  ? 235 PHE B CZ  1 
ATOM 3555 N N   . PRO B 2 246 ? 82.960  108.944 70.588  1.00 82.78  ? 236 PRO B N   1 
ATOM 3556 C CA  . PRO B 2 246 ? 83.237  107.625 69.993  1.00 82.40  ? 236 PRO B CA  1 
ATOM 3557 C C   . PRO B 2 246 ? 82.951  107.536 68.501  1.00 82.29  ? 236 PRO B C   1 
ATOM 3558 O O   . PRO B 2 246 ? 83.567  106.708 67.819  1.00 85.04  ? 236 PRO B O   1 
ATOM 3559 C CB  . PRO B 2 246 ? 82.332  106.688 70.801  1.00 82.78  ? 236 PRO B CB  1 
ATOM 3560 C CG  . PRO B 2 246 ? 82.238  107.343 72.132  1.00 86.96  ? 236 PRO B CG  1 
ATOM 3561 C CD  . PRO B 2 246 ? 82.225  108.825 71.860  1.00 85.29  ? 236 PRO B CD  1 
ATOM 3562 N N   . ASN B 2 247 ? 82.040  108.350 67.966  1.00 83.37  ? 237 ASN B N   1 
ATOM 3563 C CA  . ASN B 2 247 ? 81.780  108.330 66.533  1.00 84.50  ? 237 ASN B CA  1 
ATOM 3564 C C   . ASN B 2 247 ? 82.673  109.281 65.746  1.00 81.65  ? 237 ASN B C   1 
ATOM 3565 O O   . ASN B 2 247 ? 82.620  109.275 64.511  1.00 85.82  ? 237 ASN B O   1 
ATOM 3566 C CB  . ASN B 2 247 ? 80.308  108.662 66.251  1.00 86.51  ? 237 ASN B CB  1 
ATOM 3567 C CG  . ASN B 2 247 ? 79.870  109.981 66.867  1.00 86.41  ? 237 ASN B CG  1 
ATOM 3568 O OD1 . ASN B 2 247 ? 80.691  110.850 67.163  1.00 85.88  ? 237 ASN B OD1 1 
ATOM 3569 N ND2 . ASN B 2 247 ? 78.566  110.134 67.062  1.00 86.52  ? 237 ASN B ND2 1 
ATOM 3570 N N   . GLY B 2 248 ? 83.484  110.091 66.422  1.00 73.48  ? 238 GLY B N   1 
ATOM 3571 C CA  . GLY B 2 248 ? 84.410  110.986 65.761  1.00 76.18  ? 238 GLY B CA  1 
ATOM 3572 C C   . GLY B 2 248 ? 83.831  112.298 65.281  1.00 79.88  ? 238 GLY B C   1 
ATOM 3573 O O   . GLY B 2 248 ? 84.569  113.099 64.694  1.00 81.80  ? 238 GLY B O   1 
ATOM 3574 N N   . ASN B 2 249 ? 82.544  112.549 65.506  1.00 91.23  ? 239 ASN B N   1 
ATOM 3575 C CA  . ASN B 2 249 ? 81.900  113.768 65.038  1.00 94.17  ? 239 ASN B CA  1 
ATOM 3576 C C   . ASN B 2 249 ? 81.826  114.850 66.107  1.00 96.38  ? 239 ASN B C   1 
ATOM 3577 O O   . ASN B 2 249 ? 81.257  115.915 65.851  1.00 99.74  ? 239 ASN B O   1 
ATOM 3578 C CB  . ASN B 2 249 ? 80.493  113.458 64.517  1.00 94.66  ? 239 ASN B CB  1 
ATOM 3579 C CG  . ASN B 2 249 ? 80.512  112.639 63.240  1.00 94.73  ? 239 ASN B CG  1 
ATOM 3580 O OD1 . ASN B 2 249 ? 81.451  112.725 62.448  1.00 92.28  ? 239 ASN B OD1 1 
ATOM 3581 N ND2 . ASN B 2 249 ? 79.472  111.841 63.032  1.00 94.96  ? 239 ASN B ND2 1 
ATOM 3582 N N   . ALA B 2 250 ? 82.383  114.607 67.290  1.00 88.63  ? 240 ALA B N   1 
ATOM 3583 C CA  . ALA B 2 250 ? 82.355  115.590 68.365  1.00 87.76  ? 240 ALA B CA  1 
ATOM 3584 C C   . ALA B 2 250 ? 83.523  115.321 69.302  1.00 85.27  ? 240 ALA B C   1 
ATOM 3585 O O   . ALA B 2 250 ? 84.164  114.269 69.243  1.00 83.20  ? 240 ALA B O   1 
ATOM 3586 C CB  . ALA B 2 250 ? 81.024  115.555 69.121  1.00 83.84  ? 240 ALA B CB  1 
ATOM 3587 N N   . PHE B 2 251 ? 83.804  116.300 70.159  1.00 88.18  ? 241 PHE B N   1 
ATOM 3588 C CA  . PHE B 2 251 ? 84.803  116.133 71.203  1.00 88.36  ? 241 PHE B CA  1 
ATOM 3589 C C   . PHE B 2 251 ? 84.436  117.010 72.391  1.00 89.70  ? 241 PHE B C   1 
ATOM 3590 O O   . PHE B 2 251 ? 83.733  118.015 72.254  1.00 92.30  ? 241 PHE B O   1 
ATOM 3591 C CB  . PHE B 2 251 ? 86.212  116.463 70.693  1.00 81.26  ? 241 PHE B CB  1 
ATOM 3592 C CG  . PHE B 2 251 ? 86.406  117.906 70.325  1.00 82.29  ? 241 PHE B CG  1 
ATOM 3593 C CD1 . PHE B 2 251 ? 86.029  118.376 69.079  1.00 86.16  ? 241 PHE B CD1 1 
ATOM 3594 C CD2 . PHE B 2 251 ? 86.977  118.791 71.223  1.00 84.56  ? 241 PHE B CD2 1 
ATOM 3595 C CE1 . PHE B 2 251 ? 86.211  119.704 68.740  1.00 89.43  ? 241 PHE B CE1 1 
ATOM 3596 C CE2 . PHE B 2 251 ? 87.163  120.116 70.889  1.00 86.60  ? 241 PHE B CE2 1 
ATOM 3597 C CZ  . PHE B 2 251 ? 86.781  120.573 69.646  1.00 88.48  ? 241 PHE B CZ  1 
ATOM 3598 N N   . ALA B 2 252 ? 84.925  116.618 73.565  1.00 65.90  ? 242 ALA B N   1 
ATOM 3599 C CA  . ALA B 2 252 ? 84.706  117.357 74.799  1.00 59.22  ? 242 ALA B CA  1 
ATOM 3600 C C   . ALA B 2 252 ? 86.033  117.834 75.370  1.00 63.51  ? 242 ALA B C   1 
ATOM 3601 O O   . ALA B 2 252 ? 87.058  117.156 75.255  1.00 65.36  ? 242 ALA B O   1 
ATOM 3602 C CB  . ALA B 2 252 ? 83.976  116.503 75.839  1.00 58.67  ? 242 ALA B CB  1 
ATOM 3603 N N   . THR B 2 253 ? 86.003  119.010 75.993  1.00 69.17  ? 243 THR B N   1 
ATOM 3604 C CA  . THR B 2 253 ? 87.179  119.613 76.601  1.00 73.18  ? 243 THR B CA  1 
ATOM 3605 C C   . THR B 2 253 ? 86.940  119.883 78.082  1.00 67.16  ? 243 THR B C   1 
ATOM 3606 O O   . THR B 2 253 ? 85.801  120.003 78.540  1.00 63.43  ? 243 THR B O   1 
ATOM 3607 C CB  . THR B 2 253 ? 87.561  120.925 75.902  1.00 74.70  ? 243 THR B CB  1 
ATOM 3608 O OG1 . THR B 2 253 ? 86.502  121.877 76.060  1.00 76.06  ? 243 THR B OG1 1 
ATOM 3609 C CG2 . THR B 2 253 ? 87.807  120.693 74.421  1.00 66.80  ? 243 THR B CG2 1 
ATOM 3610 N N   . GLY B 2 254 ? 88.039  119.974 78.826  1.00 61.32  ? 244 GLY B N   1 
ATOM 3611 C CA  . GLY B 2 254 ? 88.002  120.377 80.219  1.00 66.95  ? 244 GLY B CA  1 
ATOM 3612 C C   . GLY B 2 254 ? 89.024  121.460 80.499  1.00 68.90  ? 244 GLY B C   1 
ATOM 3613 O O   . GLY B 2 254 ? 90.183  121.337 80.094  1.00 69.56  ? 244 GLY B O   1 
ATOM 3614 N N   . SER B 2 255 ? 88.616  122.521 81.188  1.00 72.78  ? 245 SER B N   1 
ATOM 3615 C CA  . SER B 2 255 ? 89.459  123.692 81.393  1.00 71.85  ? 245 SER B CA  1 
ATOM 3616 C C   . SER B 2 255 ? 89.621  123.984 82.884  1.00 77.06  ? 245 SER B C   1 
ATOM 3617 O O   . SER B 2 255 ? 89.041  123.318 83.744  1.00 87.31  ? 245 SER B O   1 
ATOM 3618 C CB  . SER B 2 255 ? 88.880  124.904 80.660  1.00 75.12  ? 245 SER B CB  1 
ATOM 3619 O OG  . SER B 2 255 ? 89.689  126.051 80.854  1.00 84.18  ? 245 SER B OG  1 
ATOM 3620 N N   . ASP B 2 256 ? 90.430  125.006 83.177  1.00 74.40  ? 246 ASP B N   1 
ATOM 3621 C CA  . ASP B 2 256 ? 90.636  125.491 84.537  1.00 73.38  ? 246 ASP B CA  1 
ATOM 3622 C C   . ASP B 2 256 ? 89.482  126.334 85.063  1.00 72.86  ? 246 ASP B C   1 
ATOM 3623 O O   . ASP B 2 256 ? 89.483  126.678 86.249  1.00 77.92  ? 246 ASP B O   1 
ATOM 3624 C CB  . ASP B 2 256 ? 91.925  126.312 84.614  1.00 74.67  ? 246 ASP B CB  1 
ATOM 3625 C CG  . ASP B 2 256 ? 93.170  125.455 84.529  1.00 78.20  ? 246 ASP B CG  1 
ATOM 3626 O OD1 . ASP B 2 256 ? 93.121  124.289 84.971  1.00 73.80  ? 246 ASP B OD1 1 
ATOM 3627 O OD2 . ASP B 2 256 ? 94.199  125.947 84.021  1.00 81.27  ? 246 ASP B OD2 1 
ATOM 3628 N N   . ASP B 2 257 ? 88.504  126.674 84.224  1.00 79.36  ? 247 ASP B N   1 
ATOM 3629 C CA  . ASP B 2 257 ? 87.355  127.463 84.644  1.00 83.46  ? 247 ASP B CA  1 
ATOM 3630 C C   . ASP B 2 257 ? 86.243  126.608 85.240  1.00 87.39  ? 247 ASP B C   1 
ATOM 3631 O O   . ASP B 2 257 ? 85.095  127.064 85.310  1.00 86.80  ? 247 ASP B O   1 
ATOM 3632 C CB  . ASP B 2 257 ? 86.821  128.288 83.470  1.00 84.60  ? 247 ASP B CB  1 
ATOM 3633 C CG  . ASP B 2 257 ? 86.454  127.434 82.270  1.00 88.81  ? 247 ASP B CG  1 
ATOM 3634 O OD1 . ASP B 2 257 ? 86.531  126.192 82.366  1.00 88.28  ? 247 ASP B OD1 1 
ATOM 3635 O OD2 . ASP B 2 257 ? 86.087  128.008 81.224  1.00 89.40  ? 247 ASP B OD2 1 
ATOM 3636 N N   . ALA B 2 258 ? 86.559  125.379 85.654  1.00 89.37  ? 248 ALA B N   1 
ATOM 3637 C CA  . ALA B 2 258 ? 85.615  124.486 86.326  1.00 87.99  ? 248 ALA B CA  1 
ATOM 3638 C C   . ALA B 2 258 ? 84.449  124.110 85.419  1.00 89.60  ? 248 ALA B C   1 
ATOM 3639 O O   . ALA B 2 258 ? 83.346  123.829 85.893  1.00 92.86  ? 248 ALA B O   1 
ATOM 3640 C CB  . ALA B 2 258 ? 85.102  125.092 87.637  1.00 86.40  ? 248 ALA B CB  1 
ATOM 3641 N N   . THR B 2 259 ? 84.681  124.098 84.108  1.00 81.51  ? 249 THR B N   1 
ATOM 3642 C CA  . THR B 2 259 ? 83.652  123.758 83.139  1.00 81.96  ? 249 THR B CA  1 
ATOM 3643 C C   . THR B 2 259 ? 84.183  122.714 82.168  1.00 85.17  ? 249 THR B C   1 
ATOM 3644 O O   . THR B 2 259 ? 85.372  122.693 81.840  1.00 87.12  ? 249 THR B O   1 
ATOM 3645 C CB  . THR B 2 259 ? 83.184  124.987 82.337  1.00 82.83  ? 249 THR B CB  1 
ATOM 3646 O OG1 . THR B 2 259 ? 84.248  125.439 81.490  1.00 85.60  ? 249 THR B OG1 1 
ATOM 3647 C CG2 . THR B 2 259 ? 82.776  126.120 83.261  1.00 85.00  ? 249 THR B CG2 1 
ATOM 3648 N N   . CYS B 2 260 ? 83.279  121.859 81.697  1.00 87.61  ? 250 CYS B N   1 
ATOM 3649 C CA  . CYS B 2 260 ? 83.540  120.957 80.587  1.00 85.53  ? 250 CYS B CA  1 
ATOM 3650 C C   . CYS B 2 260 ? 82.591  121.312 79.456  1.00 87.02  ? 250 CYS B C   1 
ATOM 3651 O O   . CYS B 2 260 ? 81.397  121.522 79.684  1.00 88.39  ? 250 CYS B O   1 
ATOM 3652 C CB  . CYS B 2 260 ? 83.350  119.490 80.989  1.00 83.54  ? 250 CYS B CB  1 
ATOM 3653 S SG  . CYS B 2 260 ? 84.873  118.591 81.341  1.00 79.16  ? 250 CYS B SG  1 
ATOM 3654 N N   . ARG B 2 261 ? 83.120  121.381 78.238  1.00 83.88  ? 251 ARG B N   1 
ATOM 3655 C CA  . ARG B 2 261 ? 82.323  121.756 77.082  1.00 85.48  ? 251 ARG B CA  1 
ATOM 3656 C C   . ARG B 2 261 ? 82.447  120.701 75.994  1.00 83.82  ? 251 ARG B C   1 
ATOM 3657 O O   . ARG B 2 261 ? 83.530  120.155 75.765  1.00 82.61  ? 251 ARG B O   1 
ATOM 3658 C CB  . ARG B 2 261 ? 82.751  123.135 76.572  1.00 87.82  ? 251 ARG B CB  1 
ATOM 3659 C CG  . ARG B 2 261 ? 82.775  124.161 77.695  1.00 89.49  ? 251 ARG B CG  1 
ATOM 3660 C CD  . ARG B 2 261 ? 82.855  125.592 77.216  1.00 89.85  ? 251 ARG B CD  1 
ATOM 3661 N NE  . ARG B 2 261 ? 82.768  126.512 78.343  1.00 91.38  ? 251 ARG B NE  1 
ATOM 3662 C CZ  . ARG B 2 261 ? 82.406  127.784 78.251  1.00 90.94  ? 251 ARG B CZ  1 
ATOM 3663 N NH1 . ARG B 2 261 ? 82.072  128.325 77.091  1.00 89.73  ? 251 ARG B NH1 1 
ATOM 3664 N NH2 . ARG B 2 261 ? 82.372  128.530 79.351  1.00 90.65  ? 251 ARG B NH2 1 
ATOM 3665 N N   . LEU B 2 262 ? 81.330  120.424 75.326  1.00 81.11  ? 252 LEU B N   1 
ATOM 3666 C CA  . LEU B 2 262 ? 81.262  119.467 74.226  1.00 81.34  ? 252 LEU B CA  1 
ATOM 3667 C C   . LEU B 2 262 ? 81.147  120.238 72.917  1.00 85.17  ? 252 LEU B C   1 
ATOM 3668 O O   . LEU B 2 262 ? 80.125  120.883 72.659  1.00 86.96  ? 252 LEU B O   1 
ATOM 3669 C CB  . LEU B 2 262 ? 80.078  118.519 74.409  1.00 84.43  ? 252 LEU B CB  1 
ATOM 3670 C CG  . LEU B 2 262 ? 79.945  117.378 73.400  1.00 86.26  ? 252 LEU B CG  1 
ATOM 3671 C CD1 . LEU B 2 262 ? 81.133  116.438 73.493  1.00 85.56  ? 252 LEU B CD1 1 
ATOM 3672 C CD2 . LEU B 2 262 ? 78.639  116.625 73.605  1.00 87.53  ? 252 LEU B CD2 1 
ATOM 3673 N N   . PHE B 2 263 ? 82.188  120.172 72.092  1.00 87.76  ? 253 PHE B N   1 
ATOM 3674 C CA  . PHE B 2 263 ? 82.188  120.824 70.790  1.00 91.20  ? 253 PHE B CA  1 
ATOM 3675 C C   . PHE B 2 263 ? 81.876  119.817 69.690  1.00 90.66  ? 253 PHE B C   1 
ATOM 3676 O O   . PHE B 2 263 ? 82.282  118.654 69.762  1.00 90.56  ? 253 PHE B O   1 
ATOM 3677 C CB  . PHE B 2 263 ? 83.537  121.490 70.512  1.00 89.78  ? 253 PHE B CB  1 
ATOM 3678 C CG  . PHE B 2 263 ? 83.948  122.491 71.554  1.00 88.27  ? 253 PHE B CG  1 
ATOM 3679 C CD1 . PHE B 2 263 ? 83.359  123.742 71.604  1.00 88.85  ? 253 PHE B CD1 1 
ATOM 3680 C CD2 . PHE B 2 263 ? 84.931  122.182 72.478  1.00 86.41  ? 253 PHE B CD2 1 
ATOM 3681 C CE1 . PHE B 2 263 ? 83.738  124.663 72.560  1.00 88.16  ? 253 PHE B CE1 1 
ATOM 3682 C CE2 . PHE B 2 263 ? 85.315  123.099 73.435  1.00 87.96  ? 253 PHE B CE2 1 
ATOM 3683 C CZ  . PHE B 2 263 ? 84.718  124.341 73.476  1.00 89.74  ? 253 PHE B CZ  1 
ATOM 3684 N N   . ASP B 2 264 ? 81.153  120.275 68.671  1.00 115.16 ? 254 ASP B N   1 
ATOM 3685 C CA  . ASP B 2 264 ? 80.815  119.468 67.505  1.00 116.08 ? 254 ASP B CA  1 
ATOM 3686 C C   . ASP B 2 264 ? 81.638  119.936 66.314  1.00 113.28 ? 254 ASP B C   1 
ATOM 3687 O O   . ASP B 2 264 ? 81.754  121.141 66.070  1.00 113.65 ? 254 ASP B O   1 
ATOM 3688 C CB  . ASP B 2 264 ? 79.322  119.558 67.183  1.00 116.32 ? 254 ASP B CB  1 
ATOM 3689 C CG  . ASP B 2 264 ? 78.910  118.614 66.069  1.00 118.77 ? 254 ASP B CG  1 
ATOM 3690 O OD1 . ASP B 2 264 ? 78.825  117.394 66.324  1.00 118.05 ? 254 ASP B OD1 1 
ATOM 3691 O OD2 . ASP B 2 264 ? 78.672  119.092 64.940  1.00 119.04 ? 254 ASP B OD2 1 
ATOM 3692 N N   . LEU B 2 265 ? 82.202  118.982 65.570  1.00 99.55  ? 255 LEU B N   1 
ATOM 3693 C CA  . LEU B 2 265 ? 83.010  119.333 64.406  1.00 103.27 ? 255 LEU B CA  1 
ATOM 3694 C C   . LEU B 2 265 ? 82.148  119.909 63.289  1.00 107.90 ? 255 LEU B C   1 
ATOM 3695 O O   . LEU B 2 265 ? 82.477  120.950 62.711  1.00 110.39 ? 255 LEU B O   1 
ATOM 3696 C CB  . LEU B 2 265 ? 83.777  118.107 63.911  1.00 102.70 ? 255 LEU B CB  1 
ATOM 3697 C CG  . LEU B 2 265 ? 84.718  117.422 64.901  1.00 102.61 ? 255 LEU B CG  1 
ATOM 3698 C CD1 . LEU B 2 265 ? 85.432  116.262 64.230  1.00 104.29 ? 255 LEU B CD1 1 
ATOM 3699 C CD2 . LEU B 2 265 ? 85.718  118.417 65.462  1.00 104.28 ? 255 LEU B CD2 1 
ATOM 3700 N N   . ARG B 2 266 ? 81.037  119.242 62.971  1.00 125.04 ? 256 ARG B N   1 
ATOM 3701 C CA  . ARG B 2 266 ? 80.237  119.633 61.816  1.00 126.07 ? 256 ARG B CA  1 
ATOM 3702 C C   . ARG B 2 266 ? 79.423  120.894 62.086  1.00 126.47 ? 256 ARG B C   1 
ATOM 3703 O O   . ARG B 2 266 ? 79.270  121.735 61.193  1.00 126.99 ? 256 ARG B O   1 
ATOM 3704 C CB  . ARG B 2 266 ? 79.325  118.481 61.392  1.00 124.99 ? 256 ARG B CB  1 
ATOM 3705 C CG  . ARG B 2 266 ? 80.082  117.263 60.884  1.00 125.78 ? 256 ARG B CG  1 
ATOM 3706 C CD  . ARG B 2 266 ? 79.142  116.171 60.397  1.00 126.45 ? 256 ARG B CD  1 
ATOM 3707 N NE  . ARG B 2 266 ? 78.272  115.673 61.456  1.00 129.09 ? 256 ARG B NE  1 
ATOM 3708 C CZ  . ARG B 2 266 ? 77.367  114.718 61.291  1.00 128.04 ? 256 ARG B CZ  1 
ATOM 3709 N NH1 . ARG B 2 266 ? 77.187  114.131 60.119  1.00 126.84 ? 256 ARG B NH1 1 
ATOM 3710 N NH2 . ARG B 2 266 ? 76.624  114.343 62.328  1.00 126.66 ? 256 ARG B NH2 1 
ATOM 3711 N N   . ALA B 2 267 ? 78.890  121.045 63.300  1.00 132.58 ? 257 ALA B N   1 
ATOM 3712 C CA  . ALA B 2 267 ? 78.205  122.282 63.655  1.00 132.54 ? 257 ALA B CA  1 
ATOM 3713 C C   . ALA B 2 267 ? 79.165  123.427 63.952  1.00 133.76 ? 257 ALA B C   1 
ATOM 3714 O O   . ALA B 2 267 ? 78.733  124.584 63.973  1.00 136.08 ? 257 ALA B O   1 
ATOM 3715 C CB  . ALA B 2 267 ? 77.293  122.053 64.862  1.00 132.70 ? 257 ALA B CB  1 
ATOM 3716 N N   . ASP B 2 268 ? 80.446  123.129 64.179  1.00 131.66 ? 258 ASP B N   1 
ATOM 3717 C CA  . ASP B 2 268 ? 81.493  124.145 64.313  1.00 131.94 ? 258 ASP B CA  1 
ATOM 3718 C C   . ASP B 2 268 ? 81.195  125.123 65.450  1.00 131.44 ? 258 ASP B C   1 
ATOM 3719 O O   . ASP B 2 268 ? 81.439  126.327 65.338  1.00 131.43 ? 258 ASP B O   1 
ATOM 3720 C CB  . ASP B 2 268 ? 81.699  124.889 62.989  1.00 133.18 ? 258 ASP B CB  1 
ATOM 3721 C CG  . ASP B 2 268 ? 82.990  125.686 62.956  1.00 132.28 ? 258 ASP B CG  1 
ATOM 3722 O OD1 . ASP B 2 268 ? 84.074  125.070 63.016  1.00 130.22 ? 258 ASP B OD1 1 
ATOM 3723 O OD2 . ASP B 2 268 ? 82.920  126.929 62.866  1.00 131.42 ? 258 ASP B OD2 1 
ATOM 3724 N N   . GLN B 2 269 ? 80.664  124.608 66.556  1.00 126.06 ? 259 GLN B N   1 
ATOM 3725 C CA  . GLN B 2 269 ? 80.351  125.447 67.706  1.00 125.66 ? 259 GLN B CA  1 
ATOM 3726 C C   . GLN B 2 269 ? 80.152  124.564 68.929  1.00 124.93 ? 259 GLN B C   1 
ATOM 3727 O O   . GLN B 2 269 ? 80.017  123.342 68.826  1.00 127.12 ? 259 GLN B O   1 
ATOM 3728 C CB  . GLN B 2 269 ? 79.111  126.311 67.454  1.00 126.28 ? 259 GLN B CB  1 
ATOM 3729 C CG  . GLN B 2 269 ? 77.892  125.537 66.987  1.00 126.59 ? 259 GLN B CG  1 
ATOM 3730 C CD  . GLN B 2 269 ? 76.727  126.444 66.646  1.00 126.36 ? 259 GLN B CD  1 
ATOM 3731 O OE1 . GLN B 2 269 ? 76.316  127.276 67.455  1.00 126.94 ? 259 GLN B OE1 1 
ATOM 3732 N NE2 . GLN B 2 269 ? 76.191  126.292 65.441  1.00 127.17 ? 259 GLN B NE2 1 
ATOM 3733 N N   . GLU B 2 270 ? 80.141  125.206 70.093  1.00 108.03 ? 260 GLU B N   1 
ATOM 3734 C CA  . GLU B 2 270 ? 79.886  124.502 71.342  1.00 106.91 ? 260 GLU B CA  1 
ATOM 3735 C C   . GLU B 2 270 ? 78.426  124.072 71.415  1.00 108.66 ? 260 GLU B C   1 
ATOM 3736 O O   . GLU B 2 270 ? 77.526  124.799 70.985  1.00 109.99 ? 260 GLU B O   1 
ATOM 3737 C CB  . GLU B 2 270 ? 80.235  125.393 72.534  1.00 105.38 ? 260 GLU B CB  1 
ATOM 3738 C CG  . GLU B 2 270 ? 79.988  124.748 73.887  1.00 109.26 ? 260 GLU B CG  1 
ATOM 3739 C CD  . GLU B 2 270 ? 80.243  125.697 75.039  1.00 111.48 ? 260 GLU B CD  1 
ATOM 3740 O OE1 . GLU B 2 270 ? 80.853  126.763 74.811  1.00 108.11 ? 260 GLU B OE1 1 
ATOM 3741 O OE2 . GLU B 2 270 ? 79.830  125.378 76.173  1.00 114.17 ? 260 GLU B OE2 1 
ATOM 3742 N N   . LEU B 2 271 ? 78.191  122.882 71.967  1.00 106.61 ? 261 LEU B N   1 
ATOM 3743 C CA  . LEU B 2 271 ? 76.838  122.366 72.127  1.00 107.52 ? 261 LEU B CA  1 
ATOM 3744 C C   . LEU B 2 271 ? 76.361  122.312 73.569  1.00 109.19 ? 261 LEU B C   1 
ATOM 3745 O O   . LEU B 2 271 ? 75.161  122.460 73.809  1.00 109.04 ? 261 LEU B O   1 
ATOM 3746 C CB  . LEU B 2 271 ? 76.728  120.960 71.525  1.00 107.54 ? 261 LEU B CB  1 
ATOM 3747 C CG  . LEU B 2 271 ? 77.013  120.809 70.030  1.00 108.74 ? 261 LEU B CG  1 
ATOM 3748 C CD1 . LEU B 2 271 ? 76.614  119.420 69.559  1.00 109.03 ? 261 LEU B CD1 1 
ATOM 3749 C CD2 . LEU B 2 271 ? 76.289  121.882 69.231  1.00 111.18 ? 261 LEU B CD2 1 
ATOM 3750 N N   . MET B 2 272 ? 77.256  122.109 74.533  1.00 107.87 ? 262 MET B N   1 
ATOM 3751 C CA  . MET B 2 272 ? 76.828  121.912 75.910  1.00 109.32 ? 262 MET B CA  1 
ATOM 3752 C C   . MET B 2 272 ? 77.999  122.176 76.845  1.00 105.63 ? 262 MET B C   1 
ATOM 3753 O O   . MET B 2 272 ? 79.152  121.896 76.511  1.00 100.77 ? 262 MET B O   1 
ATOM 3754 C CB  . MET B 2 272 ? 76.272  120.497 76.113  1.00 110.42 ? 262 MET B CB  1 
ATOM 3755 C CG  . MET B 2 272 ? 75.745  120.206 77.505  1.00 107.01 ? 262 MET B CG  1 
ATOM 3756 S SD  . MET B 2 272 ? 74.494  118.910 77.485  1.00 111.18 ? 262 MET B SD  1 
ATOM 3757 C CE  . MET B 2 272 ? 73.091  119.814 76.837  1.00 109.79 ? 262 MET B CE  1 
ATOM 3758 N N   . THR B 2 273 ? 77.683  122.719 78.020  1.00 101.08 ? 263 THR B N   1 
ATOM 3759 C CA  . THR B 2 273 ? 78.659  122.992 79.065  1.00 100.83 ? 263 THR B CA  1 
ATOM 3760 C C   . THR B 2 273 ? 78.332  122.153 80.292  1.00 101.26 ? 263 THR B C   1 
ATOM 3761 O O   . THR B 2 273 ? 77.166  122.038 80.683  1.00 103.37 ? 263 THR B O   1 
ATOM 3762 C CB  . THR B 2 273 ? 78.676  124.481 79.437  1.00 100.49 ? 263 THR B CB  1 
ATOM 3763 O OG1 . THR B 2 273 ? 78.886  125.268 78.259  1.00 102.00 ? 263 THR B OG1 1 
ATOM 3764 C CG2 . THR B 2 273 ? 79.787  124.774 80.435  1.00 97.59  ? 263 THR B CG2 1 
ATOM 3765 N N   . TYR B 2 274 ? 79.362  121.567 80.898  1.00 93.70  ? 264 TYR B N   1 
ATOM 3766 C CA  . TYR B 2 274 ? 79.210  120.688 82.057  1.00 95.93  ? 264 TYR B CA  1 
ATOM 3767 C C   . TYR B 2 274 ? 79.921  121.345 83.237  1.00 94.81  ? 264 TYR B C   1 
ATOM 3768 O O   . TYR B 2 274 ? 81.121  121.149 83.442  1.00 96.31  ? 264 TYR B O   1 
ATOM 3769 C CB  . TYR B 2 274 ? 79.769  119.291 81.773  1.00 95.88  ? 264 TYR B CB  1 
ATOM 3770 C CG  . TYR B 2 274 ? 79.295  118.685 80.472  1.00 94.73  ? 264 TYR B CG  1 
ATOM 3771 C CD1 . TYR B 2 274 ? 78.043  118.097 80.372  1.00 95.58  ? 264 TYR B CD1 1 
ATOM 3772 C CD2 . TYR B 2 274 ? 80.105  118.693 79.345  1.00 92.65  ? 264 TYR B CD2 1 
ATOM 3773 C CE1 . TYR B 2 274 ? 77.607  117.541 79.185  1.00 96.93  ? 264 TYR B CE1 1 
ATOM 3774 C CE2 . TYR B 2 274 ? 79.679  118.139 78.154  1.00 93.55  ? 264 TYR B CE2 1 
ATOM 3775 C CZ  . TYR B 2 274 ? 78.430  117.564 78.080  1.00 94.19  ? 264 TYR B CZ  1 
ATOM 3776 O OH  . TYR B 2 274 ? 78.002  117.011 76.895  1.00 92.78  ? 264 TYR B OH  1 
ATOM 3777 N N   . SER B 2 275 ? 79.173  122.127 84.013  1.00 91.99  ? 265 SER B N   1 
ATOM 3778 C CA  . SER B 2 275 ? 79.728  122.800 85.178  1.00 91.30  ? 265 SER B CA  1 
ATOM 3779 C C   . SER B 2 275 ? 78.671  122.873 86.269  1.00 89.40  ? 265 SER B C   1 
ATOM 3780 O O   . SER B 2 275 ? 77.468  122.801 86.005  1.00 94.20  ? 265 SER B O   1 
ATOM 3781 C CB  . SER B 2 275 ? 80.228  124.206 84.832  1.00 94.08  ? 265 SER B CB  1 
ATOM 3782 O OG  . SER B 2 275 ? 79.172  125.018 84.349  1.00 95.79  ? 265 SER B OG  1 
ATOM 3783 N N   . HIS B 2 276 ? 79.141  123.015 87.506  1.00 87.99  ? 266 HIS B N   1 
ATOM 3784 C CA  . HIS B 2 276 ? 78.276  123.169 88.664  1.00 91.03  ? 266 HIS B CA  1 
ATOM 3785 C C   . HIS B 2 276 ? 78.787  124.316 89.524  1.00 95.22  ? 266 HIS B C   1 
ATOM 3786 O O   . HIS B 2 276 ? 79.974  124.651 89.497  1.00 94.36  ? 266 HIS B O   1 
ATOM 3787 C CB  . HIS B 2 276 ? 78.202  121.880 89.492  1.00 93.18  ? 266 HIS B CB  1 
ATOM 3788 C CG  . HIS B 2 276 ? 76.944  121.751 90.294  1.00 93.38  ? 266 HIS B CG  1 
ATOM 3789 N ND1 . HIS B 2 276 ? 76.925  121.827 91.670  1.00 93.71  ? 266 HIS B ND1 1 
ATOM 3790 C CD2 . HIS B 2 276 ? 75.661  121.555 89.910  1.00 93.39  ? 266 HIS B CD2 1 
ATOM 3791 C CE1 . HIS B 2 276 ? 75.684  121.680 92.099  1.00 94.81  ? 266 HIS B CE1 1 
ATOM 3792 N NE2 . HIS B 2 276 ? 74.898  121.514 91.052  1.00 95.80  ? 266 HIS B NE2 1 
ATOM 3793 N N   . ASP B 2 277 ? 77.873  124.921 90.287  1.00 107.72 ? 267 ASP B N   1 
ATOM 3794 C CA  . ASP B 2 277 ? 78.246  126.062 91.116  1.00 107.76 ? 267 ASP B CA  1 
ATOM 3795 C C   . ASP B 2 277 ? 79.196  125.657 92.236  1.00 105.62 ? 267 ASP B C   1 
ATOM 3796 O O   . ASP B 2 277 ? 80.077  126.439 92.610  1.00 105.08 ? 267 ASP B O   1 
ATOM 3797 C CB  . ASP B 2 277 ? 76.996  126.726 91.693  1.00 105.72 ? 267 ASP B CB  1 
ATOM 3798 C CG  . ASP B 2 277 ? 76.047  127.213 90.617  1.00 106.45 ? 267 ASP B CG  1 
ATOM 3799 O OD1 . ASP B 2 277 ? 75.440  126.365 89.930  1.00 106.57 ? 267 ASP B OD1 1 
ATOM 3800 O OD2 . ASP B 2 277 ? 75.907  128.444 90.459  1.00 106.76 ? 267 ASP B OD2 1 
ATOM 3801 N N   . ASN B 2 278 ? 79.033  124.450 92.783  1.00 105.55 ? 268 ASN B N   1 
ATOM 3802 C CA  . ASN B 2 278 ? 79.952  123.979 93.813  1.00 107.71 ? 268 ASN B CA  1 
ATOM 3803 C C   . ASN B 2 278 ? 81.350  123.751 93.254  1.00 107.50 ? 268 ASN B C   1 
ATOM 3804 O O   . ASN B 2 278 ? 82.336  123.859 93.992  1.00 106.87 ? 268 ASN B O   1 
ATOM 3805 C CB  . ASN B 2 278 ? 79.418  122.696 94.448  1.00 107.00 ? 268 ASN B CB  1 
ATOM 3806 C CG  . ASN B 2 278 ? 78.109  122.910 95.181  1.00 108.55 ? 268 ASN B CG  1 
ATOM 3807 O OD1 . ASN B 2 278 ? 77.033  122.819 94.591  1.00 110.43 ? 268 ASN B OD1 1 
ATOM 3808 N ND2 . ASN B 2 278 ? 78.195  123.196 96.474  1.00 107.74 ? 268 ASN B ND2 1 
ATOM 3809 N N   . ILE B 2 279 ? 81.457  123.440 91.967  1.00 94.10  ? 269 ILE B N   1 
ATOM 3810 C CA  . ILE B 2 279 ? 82.743  123.127 91.354  1.00 91.52  ? 269 ILE B CA  1 
ATOM 3811 C C   . ILE B 2 279 ? 83.440  124.433 90.999  1.00 93.78  ? 269 ILE B C   1 
ATOM 3812 O O   . ILE B 2 279 ? 82.941  125.213 90.181  1.00 93.54  ? 269 ILE B O   1 
ATOM 3813 C CB  . ILE B 2 279 ? 82.566  122.240 90.114  1.00 90.60  ? 269 ILE B CB  1 
ATOM 3814 C CG1 . ILE B 2 279 ? 81.858  120.936 90.487  1.00 89.60  ? 269 ILE B CG1 1 
ATOM 3815 C CG2 . ILE B 2 279 ? 83.913  121.950 89.476  1.00 91.15  ? 269 ILE B CG2 1 
ATOM 3816 C CD1 . ILE B 2 279 ? 81.651  120.000 89.317  1.00 93.76  ? 269 ILE B CD1 1 
ATOM 3817 N N   . ILE B 2 280 ? 84.596  124.675 91.615  1.00 98.19  ? 270 ILE B N   1 
ATOM 3818 C CA  . ILE B 2 280 ? 85.356  125.898 91.388  1.00 98.46  ? 270 ILE B CA  1 
ATOM 3819 C C   . ILE B 2 280 ? 86.797  125.533 91.060  1.00 99.92  ? 270 ILE B C   1 
ATOM 3820 O O   . ILE B 2 280 ? 87.664  126.408 90.953  1.00 98.77  ? 270 ILE B O   1 
ATOM 3821 C CB  . ILE B 2 280 ? 85.290  126.834 92.609  1.00 97.67  ? 270 ILE B CB  1 
ATOM 3822 C CG1 . ILE B 2 280 ? 85.834  126.125 93.851  1.00 99.23  ? 270 ILE B CG1 1 
ATOM 3823 C CG2 . ILE B 2 280 ? 83.865  127.317 92.839  1.00 96.64  ? 270 ILE B CG2 1 
ATOM 3824 C CD1 . ILE B 2 280 ? 85.843  126.987 95.093  1.00 97.72  ? 270 ILE B CD1 1 
ATOM 3825 N N   . CYS B 2 281 ? 87.059  124.242 90.899  1.00 89.43  ? 271 CYS B N   1 
ATOM 3826 C CA  . CYS B 2 281 ? 88.399  123.738 90.652  1.00 85.83  ? 271 CYS B CA  1 
ATOM 3827 C C   . CYS B 2 281 ? 88.584  123.372 89.183  1.00 86.98  ? 271 CYS B C   1 
ATOM 3828 O O   . CYS B 2 281 ? 87.621  123.165 88.441  1.00 85.77  ? 271 CYS B O   1 
ATOM 3829 C CB  . CYS B 2 281 ? 88.672  122.520 91.535  1.00 86.18  ? 271 CYS B CB  1 
ATOM 3830 S SG  . CYS B 2 281 ? 87.545  121.139 91.237  1.00 99.21  ? 271 CYS B SG  1 
ATOM 3831 N N   . GLY B 2 282 ? 89.848  123.289 88.773  1.00 75.18  ? 272 GLY B N   1 
ATOM 3832 C CA  . GLY B 2 282 ? 90.161  122.957 87.399  1.00 70.91  ? 272 GLY B CA  1 
ATOM 3833 C C   . GLY B 2 282 ? 89.902  121.500 87.064  1.00 69.02  ? 272 GLY B C   1 
ATOM 3834 O O   . GLY B 2 282 ? 89.802  120.631 87.930  1.00 74.01  ? 272 GLY B O   1 
ATOM 3835 N N   . ILE B 2 283 ? 89.780  121.241 85.764  1.00 54.00  ? 273 ILE B N   1 
ATOM 3836 C CA  . ILE B 2 283 ? 89.542  119.906 85.227  1.00 43.08  ? 273 ILE B CA  1 
ATOM 3837 C C   . ILE B 2 283 ? 90.825  119.427 84.563  1.00 41.77  ? 273 ILE B C   1 
ATOM 3838 O O   . ILE B 2 283 ? 91.457  120.178 83.810  1.00 60.05  ? 273 ILE B O   1 
ATOM 3839 C CB  . ILE B 2 283 ? 88.365  119.906 84.239  1.00 41.85  ? 273 ILE B CB  1 
ATOM 3840 C CG1 . ILE B 2 283 ? 87.131  120.494 84.920  1.00 51.21  ? 273 ILE B CG1 1 
ATOM 3841 C CG2 . ILE B 2 283 ? 88.091  118.501 83.731  1.00 47.01  ? 273 ILE B CG2 1 
ATOM 3842 C CD1 . ILE B 2 283 ? 85.892  120.479 84.080  1.00 58.21  ? 273 ILE B CD1 1 
ATOM 3843 N N   . THR B 2 284 ? 91.214  118.182 84.842  1.00 37.05  ? 274 THR B N   1 
ATOM 3844 C CA  . THR B 2 284 ? 92.481  117.646 84.361  1.00 46.02  ? 274 THR B CA  1 
ATOM 3845 C C   . THR B 2 284 ? 92.355  116.646 83.221  1.00 51.28  ? 274 THR B C   1 
ATOM 3846 O O   . THR B 2 284 ? 93.249  116.588 82.375  1.00 51.03  ? 274 THR B O   1 
ATOM 3847 C CB  . THR B 2 284 ? 93.248  116.983 85.511  1.00 43.67  ? 274 THR B CB  1 
ATOM 3848 O OG1 . THR B 2 284 ? 92.410  116.015 86.151  1.00 50.78  ? 274 THR B OG1 1 
ATOM 3849 C CG2 . THR B 2 284 ? 93.675  118.025 86.528  1.00 46.32  ? 274 THR B CG2 1 
ATOM 3850 N N   . SER B 2 285 ? 91.284  115.855 83.171  1.00 54.13  ? 275 SER B N   1 
ATOM 3851 C CA  . SER B 2 285 ? 91.185  114.792 82.181  1.00 50.72  ? 275 SER B CA  1 
ATOM 3852 C C   . SER B 2 285 ? 89.726  114.519 81.854  1.00 47.30  ? 275 SER B C   1 
ATOM 3853 O O   . SER B 2 285 ? 88.847  114.666 82.707  1.00 59.50  ? 275 SER B O   1 
ATOM 3854 C CB  . SER B 2 285 ? 91.853  113.508 82.673  1.00 54.15  ? 275 SER B CB  1 
ATOM 3855 O OG  . SER B 2 285 ? 91.309  113.105 83.916  1.00 64.81  ? 275 SER B OG  1 
ATOM 3856 N N   . VAL B 2 286 ? 89.478  114.116 80.607  1.00 34.07  ? 276 VAL B N   1 
ATOM 3857 C CA  . VAL B 2 286 ? 88.140  113.776 80.141  1.00 41.25  ? 276 VAL B CA  1 
ATOM 3858 C C   . VAL B 2 286 ? 88.218  112.536 79.260  1.00 48.73  ? 276 VAL B C   1 
ATOM 3859 O O   . VAL B 2 286 ? 89.217  112.299 78.574  1.00 60.91  ? 276 VAL B O   1 
ATOM 3860 C CB  . VAL B 2 286 ? 87.472  114.937 79.369  1.00 44.90  ? 276 VAL B CB  1 
ATOM 3861 C CG1 . VAL B 2 286 ? 87.197  116.110 80.294  1.00 49.44  ? 276 VAL B CG1 1 
ATOM 3862 C CG2 . VAL B 2 286 ? 88.340  115.369 78.196  1.00 57.39  ? 276 VAL B CG2 1 
ATOM 3863 N N   . SER B 2 287 ? 87.155  111.737 79.295  1.00 54.79  ? 277 SER B N   1 
ATOM 3864 C CA  . SER B 2 287 ? 87.044  110.554 78.455  1.00 49.73  ? 277 SER B CA  1 
ATOM 3865 C C   . SER B 2 287 ? 85.571  110.205 78.314  1.00 57.19  ? 277 SER B C   1 
ATOM 3866 O O   . SER B 2 287 ? 84.736  110.634 79.114  1.00 68.93  ? 277 SER B O   1 
ATOM 3867 C CB  . SER B 2 287 ? 87.831  109.373 79.031  1.00 45.31  ? 277 SER B CB  1 
ATOM 3868 O OG  . SER B 2 287 ? 87.734  108.237 78.190  1.00 56.99  ? 277 SER B OG  1 
ATOM 3869 N N   . PHE B 2 288 ? 85.260  109.422 77.285  1.00 66.29  ? 278 PHE B N   1 
ATOM 3870 C CA  . PHE B 2 288 ? 83.899  108.971 77.044  1.00 73.87  ? 278 PHE B CA  1 
ATOM 3871 C C   . PHE B 2 288 ? 83.779  107.466 77.249  1.00 78.94  ? 278 PHE B C   1 
ATOM 3872 O O   . PHE B 2 288 ? 84.735  106.713 77.044  1.00 82.13  ? 278 PHE B O   1 
ATOM 3873 C CB  . PHE B 2 288 ? 83.443  109.333 75.628  1.00 70.67  ? 278 PHE B CB  1 
ATOM 3874 C CG  . PHE B 2 288 ? 83.074  110.776 75.461  1.00 68.35  ? 278 PHE B CG  1 
ATOM 3875 C CD1 . PHE B 2 288 ? 81.774  111.198 75.683  1.00 73.76  ? 278 PHE B CD1 1 
ATOM 3876 C CD2 . PHE B 2 288 ? 84.021  111.711 75.080  1.00 70.00  ? 278 PHE B CD2 1 
ATOM 3877 C CE1 . PHE B 2 288 ? 81.426  112.522 75.529  1.00 74.85  ? 278 PHE B CE1 1 
ATOM 3878 C CE2 . PHE B 2 288 ? 83.678  113.037 74.925  1.00 76.24  ? 278 PHE B CE2 1 
ATOM 3879 C CZ  . PHE B 2 288 ? 82.378  113.443 75.150  1.00 77.23  ? 278 PHE B CZ  1 
ATOM 3880 N N   . SER B 2 289 ? 82.583  107.039 77.644  1.00 84.27  ? 279 SER B N   1 
ATOM 3881 C CA  . SER B 2 289 ? 82.234  105.629 77.654  1.00 82.60  ? 279 SER B CA  1 
ATOM 3882 C C   . SER B 2 289 ? 82.010  105.130 76.228  1.00 79.08  ? 279 SER B C   1 
ATOM 3883 O O   . SER B 2 289 ? 82.000  105.899 75.262  1.00 77.07  ? 279 SER B O   1 
ATOM 3884 C CB  . SER B 2 289 ? 80.990  105.391 78.508  1.00 87.07  ? 279 SER B CB  1 
ATOM 3885 O OG  . SER B 2 289 ? 79.895  106.155 78.035  1.00 88.48  ? 279 SER B OG  1 
ATOM 3886 N N   . LYS B 2 290 ? 81.841  103.810 76.101  1.00 83.93  ? 280 LYS B N   1 
ATOM 3887 C CA  . LYS B 2 290 ? 81.786  103.198 74.777  1.00 85.88  ? 280 LYS B CA  1 
ATOM 3888 C C   . LYS B 2 290 ? 80.608  103.729 73.968  1.00 89.69  ? 280 LYS B C   1 
ATOM 3889 O O   . LYS B 2 290 ? 80.744  104.006 72.771  1.00 92.86  ? 280 LYS B O   1 
ATOM 3890 C CB  . LYS B 2 290 ? 81.705  101.677 74.900  1.00 88.70  ? 280 LYS B CB  1 
ATOM 3891 C CG  . LYS B 2 290 ? 81.637  100.953 73.562  1.00 88.92  ? 280 LYS B CG  1 
ATOM 3892 C CD  . LYS B 2 290 ? 81.487  99.452  73.749  1.00 91.61  ? 280 LYS B CD  1 
ATOM 3893 C CE  . LYS B 2 290 ? 81.452  98.720  72.414  1.00 89.98  ? 280 LYS B CE  1 
ATOM 3894 N NZ  . LYS B 2 290 ? 82.695  98.928  71.623  1.00 87.31  ? 280 LYS B NZ  1 
ATOM 3895 N N   . SER B 2 291 ? 79.445  103.884 74.604  1.00 91.43  ? 281 SER B N   1 
ATOM 3896 C CA  . SER B 2 291 ? 78.293  104.459 73.923  1.00 92.99  ? 281 SER B CA  1 
ATOM 3897 C C   . SER B 2 291 ? 78.309  105.981 73.899  1.00 92.84  ? 281 SER B C   1 
ATOM 3898 O O   . SER B 2 291 ? 77.493  106.580 73.191  1.00 93.20  ? 281 SER B O   1 
ATOM 3899 C CB  . SER B 2 291 ? 76.997  103.980 74.583  1.00 93.64  ? 281 SER B CB  1 
ATOM 3900 O OG  . SER B 2 291 ? 76.930  104.392 75.938  1.00 94.93  ? 281 SER B OG  1 
ATOM 3901 N N   . GLY B 2 292 ? 79.204  106.619 74.648  1.00 94.07  ? 282 GLY B N   1 
ATOM 3902 C CA  . GLY B 2 292 ? 79.240  108.063 74.710  1.00 92.60  ? 282 GLY B CA  1 
ATOM 3903 C C   . GLY B 2 292 ? 78.226  108.695 75.636  1.00 92.40  ? 282 GLY B C   1 
ATOM 3904 O O   . GLY B 2 292 ? 78.197  109.928 75.741  1.00 98.13  ? 282 GLY B O   1 
ATOM 3905 N N   . ARG B 2 293 ? 77.392  107.898 76.309  1.00 82.45  ? 283 ARG B N   1 
ATOM 3906 C CA  . ARG B 2 293 ? 76.373  108.468 77.182  1.00 82.74  ? 283 ARG B CA  1 
ATOM 3907 C C   . ARG B 2 293 ? 76.979  109.073 78.442  1.00 82.75  ? 283 ARG B C   1 
ATOM 3908 O O   . ARG B 2 293 ? 76.414  110.018 79.004  1.00 89.69  ? 283 ARG B O   1 
ATOM 3909 C CB  . ARG B 2 293 ? 75.336  107.404 77.545  1.00 84.91  ? 283 ARG B CB  1 
ATOM 3910 C CG  . ARG B 2 293 ? 74.159  107.926 78.360  1.00 85.09  ? 283 ARG B CG  1 
ATOM 3911 C CD  . ARG B 2 293 ? 73.474  109.098 77.668  1.00 85.08  ? 283 ARG B CD  1 
ATOM 3912 N NE  . ARG B 2 293 ? 72.492  109.745 78.531  1.00 84.61  ? 283 ARG B NE  1 
ATOM 3913 C CZ  . ARG B 2 293 ? 71.201  109.445 78.557  1.00 84.19  ? 283 ARG B CZ  1 
ATOM 3914 N NH1 . ARG B 2 293 ? 70.692  108.507 77.775  1.00 84.45  ? 283 ARG B NH1 1 
ATOM 3915 N NH2 . ARG B 2 293 ? 70.400  110.101 79.391  1.00 85.89  ? 283 ARG B NH2 1 
ATOM 3916 N N   . LEU B 2 294 ? 78.120  108.561 78.894  1.00 65.96  ? 284 LEU B N   1 
ATOM 3917 C CA  . LEU B 2 294 ? 78.779  109.067 80.090  1.00 70.13  ? 284 LEU B CA  1 
ATOM 3918 C C   . LEU B 2 294 ? 80.054  109.808 79.711  1.00 67.16  ? 284 LEU B C   1 
ATOM 3919 O O   . LEU B 2 294 ? 80.849  109.317 78.902  1.00 66.32  ? 284 LEU B O   1 
ATOM 3920 C CB  . LEU B 2 294 ? 79.103  107.929 81.062  1.00 62.36  ? 284 LEU B CB  1 
ATOM 3921 C CG  . LEU B 2 294 ? 77.921  107.162 81.657  1.00 68.95  ? 284 LEU B CG  1 
ATOM 3922 C CD1 . LEU B 2 294 ? 78.407  106.130 82.661  1.00 69.91  ? 284 LEU B CD1 1 
ATOM 3923 C CD2 . LEU B 2 294 ? 76.942  108.122 82.310  1.00 68.08  ? 284 LEU B CD2 1 
ATOM 3924 N N   . LEU B 2 295 ? 80.240  110.985 80.301  1.00 54.49  ? 285 LEU B N   1 
ATOM 3925 C CA  . LEU B 2 295 ? 81.467  111.766 80.188  1.00 45.89  ? 285 LEU B CA  1 
ATOM 3926 C C   . LEU B 2 295 ? 82.104  111.827 81.570  1.00 50.29  ? 285 LEU B C   1 
ATOM 3927 O O   . LEU B 2 295 ? 81.531  112.408 82.497  1.00 58.65  ? 285 LEU B O   1 
ATOM 3928 C CB  . LEU B 2 295 ? 81.184  113.164 79.643  1.00 46.88  ? 285 LEU B CB  1 
ATOM 3929 C CG  . LEU B 2 295 ? 82.344  114.161 79.696  1.00 52.25  ? 285 LEU B CG  1 
ATOM 3930 C CD1 . LEU B 2 295 ? 83.523  113.671 78.873  1.00 55.82  ? 285 LEU B CD1 1 
ATOM 3931 C CD2 . LEU B 2 295 ? 81.892  115.532 79.221  1.00 50.95  ? 285 LEU B CD2 1 
ATOM 3932 N N   . LEU B 2 296 ? 83.280  111.228 81.712  1.00 41.92  ? 286 LEU B N   1 
ATOM 3933 C CA  . LEU B 2 296 ? 83.988  111.200 82.985  1.00 44.33  ? 286 LEU B CA  1 
ATOM 3934 C C   . LEU B 2 296 ? 85.092  112.247 82.984  1.00 45.35  ? 286 LEU B C   1 
ATOM 3935 O O   . LEU B 2 296 ? 85.907  112.296 82.057  1.00 62.37  ? 286 LEU B O   1 
ATOM 3936 C CB  . LEU B 2 296 ? 84.571  109.812 83.253  1.00 40.09  ? 286 LEU B CB  1 
ATOM 3937 C CG  . LEU B 2 296 ? 83.564  108.682 83.485  1.00 48.44  ? 286 LEU B CG  1 
ATOM 3938 C CD1 . LEU B 2 296 ? 83.118  108.056 82.171  1.00 48.81  ? 286 LEU B CD1 1 
ATOM 3939 C CD2 . LEU B 2 296 ? 84.139  107.628 84.414  1.00 48.88  ? 286 LEU B CD2 1 
ATOM 3940 N N   . ALA B 2 297 ? 85.111  113.085 84.018  1.00 42.86  ? 287 ALA B N   1 
ATOM 3941 C CA  . ALA B 2 297 ? 86.059  114.184 84.123  1.00 46.80  ? 287 ALA B CA  1 
ATOM 3942 C C   . ALA B 2 297 ? 86.717  114.163 85.493  1.00 46.66  ? 287 ALA B C   1 
ATOM 3943 O O   . ALA B 2 297 ? 86.042  113.995 86.513  1.00 55.72  ? 287 ALA B O   1 
ATOM 3944 C CB  . ALA B 2 297 ? 85.375  115.535 83.889  1.00 51.35  ? 287 ALA B CB  1 
ATOM 3945 N N   . GLY B 2 298 ? 88.037  114.339 85.513  1.00 44.00  ? 288 GLY B N   1 
ATOM 3946 C CA  . GLY B 2 298 ? 88.762  114.464 86.760  1.00 46.25  ? 288 GLY B CA  1 
ATOM 3947 C C   . GLY B 2 298 ? 88.962  115.916 87.156  1.00 52.35  ? 288 GLY B C   1 
ATOM 3948 O O   . GLY B 2 298 ? 89.151  116.790 86.316  1.00 64.88  ? 288 GLY B O   1 
ATOM 3949 N N   . TYR B 2 299 ? 88.923  116.164 88.463  1.00 45.01  ? 289 TYR B N   1 
ATOM 3950 C CA  . TYR B 2 299 ? 88.888  117.516 88.994  1.00 41.14  ? 289 TYR B CA  1 
ATOM 3951 C C   . TYR B 2 299 ? 89.985  117.699 90.034  1.00 42.97  ? 289 TYR B C   1 
ATOM 3952 O O   . TYR B 2 299 ? 90.557  116.735 90.548  1.00 50.03  ? 289 TYR B O   1 
ATOM 3953 C CB  . TYR B 2 299 ? 87.520  117.841 89.610  1.00 40.88  ? 289 TYR B CB  1 
ATOM 3954 C CG  . TYR B 2 299 ? 86.392  117.929 88.606  1.00 39.85  ? 289 TYR B CG  1 
ATOM 3955 C CD1 . TYR B 2 299 ? 85.792  116.784 88.106  1.00 47.61  ? 289 TYR B CD1 1 
ATOM 3956 C CD2 . TYR B 2 299 ? 85.922  119.158 88.168  1.00 45.64  ? 289 TYR B CD2 1 
ATOM 3957 C CE1 . TYR B 2 299 ? 84.762  116.860 87.190  1.00 47.49  ? 289 TYR B CE1 1 
ATOM 3958 C CE2 . TYR B 2 299 ? 84.889  119.243 87.255  1.00 53.58  ? 289 TYR B CE2 1 
ATOM 3959 C CZ  . TYR B 2 299 ? 84.315  118.091 86.768  1.00 54.61  ? 289 TYR B CZ  1 
ATOM 3960 O OH  . TYR B 2 299 ? 83.288  118.167 85.857  1.00 55.96  ? 289 TYR B OH  1 
ATOM 3961 N N   . ASP B 2 300 ? 90.270  118.968 90.334  1.00 55.02  ? 290 ASP B N   1 
ATOM 3962 C CA  . ASP B 2 300 ? 91.233  119.314 91.374  1.00 62.31  ? 290 ASP B CA  1 
ATOM 3963 C C   . ASP B 2 300 ? 90.702  119.060 92.779  1.00 67.81  ? 290 ASP B C   1 
ATOM 3964 O O   . ASP B 2 300 ? 91.498  118.976 93.720  1.00 71.65  ? 290 ASP B O   1 
ATOM 3965 C CB  . ASP B 2 300 ? 91.653  120.778 91.237  1.00 57.77  ? 290 ASP B CB  1 
ATOM 3966 C CG  . ASP B 2 300 ? 92.170  121.111 89.853  1.00 65.85  ? 290 ASP B CG  1 
ATOM 3967 O OD1 . ASP B 2 300 ? 92.332  120.181 89.036  1.00 71.35  ? 290 ASP B OD1 1 
ATOM 3968 O OD2 . ASP B 2 300 ? 92.431  122.303 89.585  1.00 69.50  ? 290 ASP B OD2 1 
ATOM 3969 N N   . ASP B 2 301 ? 89.383  118.936 92.949  1.00 68.10  ? 291 ASP B N   1 
ATOM 3970 C CA  . ASP B 2 301 ? 88.784  118.776 94.270  1.00 63.28  ? 291 ASP B CA  1 
ATOM 3971 C C   . ASP B 2 301 ? 88.831  117.338 94.777  1.00 62.92  ? 291 ASP B C   1 
ATOM 3972 O O   . ASP B 2 301 ? 87.993  116.962 95.606  1.00 64.23  ? 291 ASP B O   1 
ATOM 3973 C CB  . ASP B 2 301 ? 87.339  119.287 94.266  1.00 66.31  ? 291 ASP B CB  1 
ATOM 3974 C CG  . ASP B 2 301 ? 86.442  118.526 93.302  1.00 72.62  ? 291 ASP B CG  1 
ATOM 3975 O OD1 . ASP B 2 301 ? 86.914  117.567 92.658  1.00 75.40  ? 291 ASP B OD1 1 
ATOM 3976 O OD2 . ASP B 2 301 ? 85.254  118.893 93.188  1.00 77.70  ? 291 ASP B OD2 1 
ATOM 3977 N N   . PHE B 2 302 ? 89.767  116.537 94.268  1.00 59.80  ? 292 PHE B N   1 
ATOM 3978 C CA  . PHE B 2 302 ? 90.093  115.175 94.700  1.00 65.07  ? 292 PHE B CA  1 
ATOM 3979 C C   . PHE B 2 302 ? 89.078  114.154 94.204  1.00 69.33  ? 292 PHE B C   1 
ATOM 3980 O O   . PHE B 2 302 ? 89.154  112.982 94.601  1.00 65.24  ? 292 PHE B O   1 
ATOM 3981 C CB  . PHE B 2 302 ? 90.209  115.041 96.225  1.00 63.33  ? 292 PHE B CB  1 
ATOM 3982 C CG  . PHE B 2 302 ? 91.124  116.054 96.871  1.00 65.71  ? 292 PHE B CG  1 
ATOM 3983 C CD1 . PHE B 2 302 ? 92.086  116.727 96.135  1.00 62.89  ? 292 PHE B CD1 1 
ATOM 3984 C CD2 . PHE B 2 302 ? 91.016  116.330 98.225  1.00 71.39  ? 292 PHE B CD2 1 
ATOM 3985 C CE1 . PHE B 2 302 ? 92.918  117.654 96.734  1.00 69.81  ? 292 PHE B CE1 1 
ATOM 3986 C CE2 . PHE B 2 302 ? 91.846  117.256 98.830  1.00 72.11  ? 292 PHE B CE2 1 
ATOM 3987 C CZ  . PHE B 2 302 ? 92.798  117.918 98.083  1.00 74.13  ? 292 PHE B CZ  1 
ATOM 3988 N N   . ASN B 2 303 ? 88.136  114.550 93.353  1.00 64.59  ? 293 ASN B N   1 
ATOM 3989 C CA  . ASN B 2 303 ? 87.050  113.683 92.927  1.00 55.99  ? 293 ASN B CA  1 
ATOM 3990 C C   . ASN B 2 303 ? 87.055  113.529 91.412  1.00 54.33  ? 293 ASN B C   1 
ATOM 3991 O O   . ASN B 2 303 ? 87.652  114.326 90.684  1.00 64.24  ? 293 ASN B O   1 
ATOM 3992 C CB  . ASN B 2 303 ? 85.691  114.229 93.388  1.00 57.13  ? 293 ASN B CB  1 
ATOM 3993 C CG  . ASN B 2 303 ? 85.639  114.474 94.881  1.00 65.99  ? 293 ASN B CG  1 
ATOM 3994 O OD1 . ASN B 2 303 ? 86.351  113.833 95.653  1.00 69.01  ? 293 ASN B OD1 1 
ATOM 3995 N ND2 . ASN B 2 303 ? 84.789  115.407 95.298  1.00 65.67  ? 293 ASN B ND2 1 
ATOM 3996 N N   . CYS B 2 304 ? 86.375  112.484 90.947  1.00 43.90  ? 294 CYS B N   1 
ATOM 3997 C CA  . CYS B 2 304 ? 86.115  112.271 89.529  1.00 35.17  ? 294 CYS B CA  1 
ATOM 3998 C C   . CYS B 2 304 ? 84.608  112.220 89.331  1.00 47.59  ? 294 CYS B C   1 
ATOM 3999 O O   . CYS B 2 304 ? 83.935  111.348 89.891  1.00 67.03  ? 294 CYS B O   1 
ATOM 4000 C CB  . CYS B 2 304 ? 86.773  110.982 89.035  1.00 40.33  ? 294 CYS B CB  1 
ATOM 4001 S SG  . CYS B 2 304 ? 86.115  110.353 87.478  1.00 59.19  ? 294 CYS B SG  1 
ATOM 4002 N N   . ASN B 2 305 ? 84.083  113.147 88.537  1.00 51.47  ? 295 ASN B N   1 
ATOM 4003 C CA  . ASN B 2 305 ? 82.651  113.246 88.288  1.00 55.54  ? 295 ASN B CA  1 
ATOM 4004 C C   . ASN B 2 305 ? 82.285  112.609 86.955  1.00 57.75  ? 295 ASN B C   1 
ATOM 4005 O O   . ASN B 2 305 ? 82.896  112.913 85.925  1.00 62.98  ? 295 ASN B O   1 
ATOM 4006 C CB  . ASN B 2 305 ? 82.197  114.706 88.302  1.00 61.49  ? 295 ASN B CB  1 
ATOM 4007 C CG  . ASN B 2 305 ? 82.345  115.349 89.664  1.00 63.41  ? 295 ASN B CG  1 
ATOM 4008 O OD1 . ASN B 2 305 ? 83.135  114.898 90.493  1.00 63.38  ? 295 ASN B OD1 1 
ATOM 4009 N ND2 . ASN B 2 305 ? 81.582  116.409 89.904  1.00 59.99  ? 295 ASN B ND2 1 
ATOM 4010 N N   . VAL B 2 306 ? 81.295  111.724 86.983  1.00 61.01  ? 296 VAL B N   1 
ATOM 4011 C CA  . VAL B 2 306 ? 80.761  111.112 85.774  1.00 58.74  ? 296 VAL B CA  1 
ATOM 4012 C C   . VAL B 2 306 ? 79.579  111.959 85.323  1.00 57.43  ? 296 VAL B C   1 
ATOM 4013 O O   . VAL B 2 306 ? 78.602  112.118 86.064  1.00 62.71  ? 296 VAL B O   1 
ATOM 4014 C CB  . VAL B 2 306 ? 80.338  109.657 86.023  1.00 67.56  ? 296 VAL B CB  1 
ATOM 4015 C CG1 . VAL B 2 306 ? 79.867  109.009 84.728  1.00 70.72  ? 296 VAL B CG1 1 
ATOM 4016 C CG2 . VAL B 2 306 ? 81.482  108.871 86.644  1.00 62.90  ? 296 VAL B CG2 1 
ATOM 4017 N N   . TRP B 2 307 ? 79.664  112.511 84.118  1.00 60.37  ? 297 TRP B N   1 
ATOM 4018 C CA  . TRP B 2 307 ? 78.628  113.391 83.602  1.00 65.58  ? 297 TRP B CA  1 
ATOM 4019 C C   . TRP B 2 307 ? 77.773  112.687 82.557  1.00 66.37  ? 297 TRP B C   1 
ATOM 4020 O O   . TRP B 2 307 ? 78.241  111.805 81.832  1.00 73.92  ? 297 TRP B O   1 
ATOM 4021 C CB  . TRP B 2 307 ? 79.240  114.658 83.000  1.00 68.62  ? 297 TRP B CB  1 
ATOM 4022 C CG  . TRP B 2 307 ? 79.943  115.514 84.004  1.00 72.51  ? 297 TRP B CG  1 
ATOM 4023 C CD1 . TRP B 2 307 ? 81.234  115.390 84.428  1.00 69.21  ? 297 TRP B CD1 1 
ATOM 4024 C CD2 . TRP B 2 307 ? 79.392  116.627 84.717  1.00 76.55  ? 297 TRP B CD2 1 
ATOM 4025 N NE1 . TRP B 2 307 ? 81.521  116.357 85.360  1.00 64.89  ? 297 TRP B NE1 1 
ATOM 4026 C CE2 . TRP B 2 307 ? 80.407  117.130 85.555  1.00 71.76  ? 297 TRP B CE2 1 
ATOM 4027 C CE3 . TRP B 2 307 ? 78.139  117.248 84.727  1.00 72.42  ? 297 TRP B CE3 1 
ATOM 4028 C CZ2 . TRP B 2 307 ? 80.209  118.223 86.393  1.00 69.08  ? 297 TRP B CZ2 1 
ATOM 4029 C CZ3 . TRP B 2 307 ? 77.944  118.334 85.560  1.00 69.88  ? 297 TRP B CZ3 1 
ATOM 4030 C CH2 . TRP B 2 307 ? 78.974  118.810 86.382  1.00 68.33  ? 297 TRP B CH2 1 
ATOM 4031 N N   . ASP B 2 308 ? 76.506  113.086 82.494  1.00 78.35  ? 298 ASP B N   1 
ATOM 4032 C CA  . ASP B 2 308 ? 75.635  112.729 81.381  1.00 77.90  ? 298 ASP B CA  1 
ATOM 4033 C C   . ASP B 2 308 ? 75.915  113.694 80.236  1.00 80.73  ? 298 ASP B C   1 
ATOM 4034 O O   . ASP B 2 308 ? 75.636  114.892 80.344  1.00 86.90  ? 298 ASP B O   1 
ATOM 4035 C CB  . ASP B 2 308 ? 74.171  112.773 81.805  1.00 84.38  ? 298 ASP B CB  1 
ATOM 4036 C CG  . ASP B 2 308 ? 73.243  112.157 80.772  1.00 90.83  ? 298 ASP B CG  1 
ATOM 4037 O OD1 . ASP B 2 308 ? 73.743  111.641 79.751  1.00 93.33  ? 298 ASP B OD1 1 
ATOM 4038 O OD2 . ASP B 2 308 ? 72.013  112.183 80.985  1.00 94.76  ? 298 ASP B OD2 1 
ATOM 4039 N N   . ALA B 2 309 ? 76.481  113.177 79.144  1.00 79.85  ? 299 ALA B N   1 
ATOM 4040 C CA  . ALA B 2 309 ? 76.883  114.040 78.037  1.00 84.14  ? 299 ALA B CA  1 
ATOM 4041 C C   . ALA B 2 309 ? 75.682  114.735 77.408  1.00 88.64  ? 299 ALA B C   1 
ATOM 4042 O O   . ALA B 2 309 ? 75.759  115.912 77.038  1.00 91.91  ? 299 ALA B O   1 
ATOM 4043 C CB  . ALA B 2 309 ? 77.643  113.229 76.988  1.00 81.36  ? 299 ALA B CB  1 
ATOM 4044 N N   . LEU B 2 310 ? 74.562  114.022 77.277  1.00 98.62  ? 300 LEU B N   1 
ATOM 4045 C CA  . LEU B 2 310 ? 73.399  114.581 76.597  1.00 99.62  ? 300 LEU B CA  1 
ATOM 4046 C C   . LEU B 2 310 ? 72.650  115.584 77.469  1.00 100.30 ? 300 LEU B C   1 
ATOM 4047 O O   . LEU B 2 310 ? 72.166  116.603 76.964  1.00 103.07 ? 300 LEU B O   1 
ATOM 4048 C CB  . LEU B 2 310 ? 72.463  113.455 76.158  1.00 98.36  ? 300 LEU B CB  1 
ATOM 4049 C CG  . LEU B 2 310 ? 73.076  112.396 75.239  1.00 98.52  ? 300 LEU B CG  1 
ATOM 4050 C CD1 . LEU B 2 310 ? 72.053  111.330 74.883  1.00 99.59  ? 300 LEU B CD1 1 
ATOM 4051 C CD2 . LEU B 2 310 ? 73.642  113.039 73.983  1.00 101.81 ? 300 LEU B CD2 1 
ATOM 4052 N N   . LYS B 2 311 ? 72.539  115.322 78.771  1.00 96.94  ? 301 LYS B N   1 
ATOM 4053 C CA  . LYS B 2 311 ? 71.701  116.131 79.647  1.00 98.89  ? 301 LYS B CA  1 
ATOM 4054 C C   . LYS B 2 311 ? 72.489  117.033 80.589  1.00 101.12 ? 301 LYS B C   1 
ATOM 4055 O O   . LYS B 2 311 ? 71.873  117.784 81.354  1.00 100.82 ? 301 LYS B O   1 
ATOM 4056 C CB  . LYS B 2 311 ? 70.774  115.225 80.467  1.00 96.82  ? 301 LYS B CB  1 
ATOM 4057 C CG  . LYS B 2 311 ? 69.881  114.328 79.626  1.00 99.02  ? 301 LYS B CG  1 
ATOM 4058 C CD  . LYS B 2 311 ? 68.884  113.576 80.492  1.00 99.89  ? 301 LYS B CD  1 
ATOM 4059 C CE  . LYS B 2 311 ? 67.926  114.531 81.184  1.00 99.40  ? 301 LYS B CE  1 
ATOM 4060 N NZ  . LYS B 2 311 ? 67.135  115.329 80.208  1.00 101.17 ? 301 LYS B NZ  1 
ATOM 4061 N N   . ALA B 2 312 ? 73.822  116.978 80.559  1.00 101.25 ? 302 ALA B N   1 
ATOM 4062 C CA  . ALA B 2 312 ? 74.676  117.835 81.388  1.00 100.62 ? 302 ALA B CA  1 
ATOM 4063 C C   . ALA B 2 312 ? 74.352  117.683 82.872  1.00 100.04 ? 302 ALA B C   1 
ATOM 4064 O O   . ALA B 2 312 ? 74.367  118.653 83.633  1.00 98.59  ? 302 ALA B O   1 
ATOM 4065 C CB  . ALA B 2 312 ? 74.579  119.302 80.962  1.00 98.90  ? 302 ALA B CB  1 
ATOM 4066 N N   . ASP B 2 313 ? 74.057  116.458 83.289  1.00 97.93  ? 303 ASP B N   1 
ATOM 4067 C CA  . ASP B 2 313 ? 73.799  116.140 84.685  1.00 97.00  ? 303 ASP B CA  1 
ATOM 4068 C C   . ASP B 2 313 ? 74.954  115.330 85.255  1.00 94.41  ? 303 ASP B C   1 
ATOM 4069 O O   . ASP B 2 313 ? 75.483  114.433 84.591  1.00 98.78  ? 303 ASP B O   1 
ATOM 4070 C CB  . ASP B 2 313 ? 72.489  115.363 84.840  1.00 97.93  ? 303 ASP B CB  1 
ATOM 4071 C CG  . ASP B 2 313 ? 71.274  116.188 84.463  1.00 100.18 ? 303 ASP B CG  1 
ATOM 4072 O OD1 . ASP B 2 313 ? 71.306  117.421 84.660  1.00 98.32  ? 303 ASP B OD1 1 
ATOM 4073 O OD2 . ASP B 2 313 ? 70.287  115.603 83.970  1.00 100.99 ? 303 ASP B OD2 1 
ATOM 4074 N N   . ARG B 2 314 ? 75.343  115.650 86.486  1.00 77.94  ? 304 ARG B N   1 
ATOM 4075 C CA  . ARG B 2 314 ? 76.374  114.880 87.175  1.00 79.83  ? 304 ARG B CA  1 
ATOM 4076 C C   . ARG B 2 314 ? 75.767  113.546 87.586  1.00 80.52  ? 304 ARG B C   1 
ATOM 4077 O O   . ARG B 2 314 ? 74.987  113.467 88.537  1.00 82.58  ? 304 ARG B O   1 
ATOM 4078 C CB  . ARG B 2 314 ? 76.905  115.639 88.386  1.00 80.41  ? 304 ARG B CB  1 
ATOM 4079 C CG  . ARG B 2 314 ? 78.060  114.936 89.087  1.00 79.11  ? 304 ARG B CG  1 
ATOM 4080 C CD  . ARG B 2 314 ? 78.322  115.515 90.469  1.00 83.89  ? 304 ARG B CD  1 
ATOM 4081 N NE  . ARG B 2 314 ? 78.626  116.941 90.428  1.00 81.57  ? 304 ARG B NE  1 
ATOM 4082 C CZ  . ARG B 2 314 ? 78.939  117.668 91.492  1.00 83.69  ? 304 ARG B CZ  1 
ATOM 4083 N NH1 . ARG B 2 314 ? 79.009  117.131 92.699  1.00 83.32  ? 304 ARG B NH1 1 
ATOM 4084 N NH2 . ARG B 2 314 ? 79.189  118.965 91.341  1.00 84.44  ? 304 ARG B NH2 1 
ATOM 4085 N N   . ALA B 2 315 ? 76.129  112.488 86.862  1.00 81.99  ? 305 ALA B N   1 
ATOM 4086 C CA  . ALA B 2 315 ? 75.522  111.183 87.088  1.00 83.87  ? 305 ALA B CA  1 
ATOM 4087 C C   . ALA B 2 315 ? 76.071  110.507 88.335  1.00 82.75  ? 305 ALA B C   1 
ATOM 4088 O O   . ALA B 2 315 ? 75.335  109.788 89.020  1.00 86.15  ? 305 ALA B O   1 
ATOM 4089 C CB  . ALA B 2 315 ? 75.736  110.289 85.868  1.00 85.09  ? 305 ALA B CB  1 
ATOM 4090 N N   . GLY B 2 316 ? 77.343  110.724 88.647  1.00 67.04  ? 306 GLY B N   1 
ATOM 4091 C CA  . GLY B 2 316 ? 77.934  110.098 89.814  1.00 65.51  ? 306 GLY B CA  1 
ATOM 4092 C C   . GLY B 2 316 ? 79.280  110.713 90.118  1.00 61.09  ? 306 GLY B C   1 
ATOM 4093 O O   . GLY B 2 316 ? 79.764  111.595 89.404  1.00 68.41  ? 306 GLY B O   1 
ATOM 4094 N N   . VAL B 2 317 ? 79.881  110.230 91.202  1.00 36.57  ? 307 VAL B N   1 
ATOM 4095 C CA  . VAL B 2 317 ? 81.166  110.725 91.683  1.00 41.17  ? 307 VAL B CA  1 
ATOM 4096 C C   . VAL B 2 317 ? 82.033  109.528 92.039  1.00 33.79  ? 307 VAL B C   1 
ATOM 4097 O O   . VAL B 2 317 ? 81.571  108.598 92.708  1.00 44.10  ? 307 VAL B O   1 
ATOM 4098 C CB  . VAL B 2 317 ? 81.005  111.654 92.903  1.00 45.40  ? 307 VAL B CB  1 
ATOM 4099 C CG1 . VAL B 2 317 ? 82.365  112.038 93.466  1.00 44.34  ? 307 VAL B CG1 1 
ATOM 4100 C CG2 . VAL B 2 317 ? 80.211  112.897 92.531  1.00 49.65  ? 307 VAL B CG2 1 
ATOM 4101 N N   . LEU B 2 318 ? 83.286  109.549 91.595  1.00 35.68  ? 308 LEU B N   1 
ATOM 4102 C CA  . LEU B 2 318 ? 84.292  108.590 92.041  1.00 31.08  ? 308 LEU B CA  1 
ATOM 4103 C C   . LEU B 2 318 ? 85.176  109.304 93.057  1.00 42.51  ? 308 LEU B C   1 
ATOM 4104 O O   . LEU B 2 318 ? 86.066  110.074 92.689  1.00 59.97  ? 308 LEU B O   1 
ATOM 4105 C CB  . LEU B 2 318 ? 85.100  108.063 90.860  1.00 39.95  ? 308 LEU B CB  1 
ATOM 4106 C CG  . LEU B 2 318 ? 84.300  107.539 89.664  1.00 48.89  ? 308 LEU B CG  1 
ATOM 4107 C CD1 . LEU B 2 318 ? 85.224  106.943 88.611  1.00 52.92  ? 308 LEU B CD1 1 
ATOM 4108 C CD2 . LEU B 2 318 ? 83.258  106.527 90.104  1.00 52.62  ? 308 LEU B CD2 1 
ATOM 4109 N N   . ALA B 2 319 ? 84.931  109.045 94.337  1.00 39.13  ? 309 ALA B N   1 
ATOM 4110 C CA  . ALA B 2 319 ? 85.667  109.672 95.431  1.00 43.08  ? 309 ALA B CA  1 
ATOM 4111 C C   . ALA B 2 319 ? 86.454  108.585 96.157  1.00 46.29  ? 309 ALA B C   1 
ATOM 4112 O O   . ALA B 2 319 ? 85.952  107.943 97.081  1.00 51.32  ? 309 ALA B O   1 
ATOM 4113 C CB  . ALA B 2 319 ? 84.721  110.404 96.377  1.00 43.74  ? 309 ALA B CB  1 
ATOM 4114 N N   . GLY B 2 320 ? 87.696  108.384 95.731  1.00 46.92  ? 310 GLY B N   1 
ATOM 4115 C CA  . GLY B 2 320 ? 88.556  107.396 96.346  1.00 51.17  ? 310 GLY B CA  1 
ATOM 4116 C C   . GLY B 2 320 ? 90.003  107.835 96.374  1.00 50.50  ? 310 GLY B C   1 
ATOM 4117 O O   . GLY B 2 320 ? 90.905  107.015 96.570  1.00 48.69  ? 310 GLY B O   1 
ATOM 4118 N N   . HIS B 2 321 ? 90.241  109.129 96.181  1.00 46.85  ? 311 HIS B N   1 
ATOM 4119 C CA  . HIS B 2 321 ? 91.591  109.658 96.110  1.00 48.86  ? 311 HIS B CA  1 
ATOM 4120 C C   . HIS B 2 321 ? 91.747  110.822 97.076  1.00 53.69  ? 311 HIS B C   1 
ATOM 4121 O O   . HIS B 2 321 ? 90.796  111.559 97.348  1.00 57.31  ? 311 HIS B O   1 
ATOM 4122 C CB  . HIS B 2 321 ? 91.929  110.117 94.687  1.00 45.98  ? 311 HIS B CB  1 
ATOM 4123 C CG  . HIS B 2 321 ? 92.111  108.991 93.717  1.00 41.81  ? 311 HIS B CG  1 
ATOM 4124 N ND1 . HIS B 2 321 ? 93.198  108.145 93.753  1.00 41.74  ? 311 HIS B ND1 1 
ATOM 4125 C CD2 . HIS B 2 321 ? 91.343  108.574 92.683  1.00 48.78  ? 311 HIS B CD2 1 
ATOM 4126 C CE1 . HIS B 2 321 ? 93.092  107.255 92.783  1.00 50.17  ? 311 HIS B CE1 1 
ATOM 4127 N NE2 . HIS B 2 321 ? 91.975  107.492 92.120  1.00 50.81  ? 311 HIS B NE2 1 
ATOM 4128 N N   . ASP B 2 322 ? 92.965  110.979 97.591  1.00 65.17  ? 312 ASP B N   1 
ATOM 4129 C CA  . ASP B 2 322 ? 93.285  112.019 98.557  1.00 63.16  ? 312 ASP B CA  1 
ATOM 4130 C C   . ASP B 2 322 ? 93.994  113.209 97.925  1.00 60.85  ? 312 ASP B C   1 
ATOM 4131 O O   . ASP B 2 322 ? 94.435  114.109 98.648  1.00 67.06  ? 312 ASP B O   1 
ATOM 4132 C CB  . ASP B 2 322 ? 94.141  111.446 99.689  1.00 64.17  ? 312 ASP B CB  1 
ATOM 4133 C CG  . ASP B 2 322 ? 93.471  110.283 100.392 1.00 65.53  ? 312 ASP B CG  1 
ATOM 4134 O OD1 . ASP B 2 322 ? 92.224  110.247 100.426 1.00 65.63  ? 312 ASP B OD1 1 
ATOM 4135 O OD2 . ASP B 2 322 ? 94.192  109.407 100.913 1.00 68.36  ? 312 ASP B OD2 1 
ATOM 4136 N N   . ASN B 2 323 ? 94.113  113.239 96.602  1.00 44.74  ? 313 ASN B N   1 
ATOM 4137 C CA  . ASN B 2 323 ? 94.690  114.385 95.915  1.00 46.02  ? 313 ASN B CA  1 
ATOM 4138 C C   . ASN B 2 323 ? 93.991  114.544 94.569  1.00 56.13  ? 313 ASN B C   1 
ATOM 4139 O O   . ASN B 2 323 ? 93.010  113.854 94.274  1.00 55.56  ? 313 ASN B O   1 
ATOM 4140 C CB  . ASN B 2 323 ? 96.208  114.216 95.773  1.00 54.36  ? 313 ASN B CB  1 
ATOM 4141 C CG  . ASN B 2 323 ? 96.933  115.542 95.663  1.00 61.39  ? 313 ASN B CG  1 
ATOM 4142 O OD1 . ASN B 2 323 ? 96.418  116.497 95.081  1.00 66.42  ? 313 ASN B OD1 1 
ATOM 4143 N ND2 . ASN B 2 323 ? 98.134  115.609 96.224  1.00 64.35  ? 313 ASN B ND2 1 
ATOM 4144 N N   . ARG B 2 324 ? 94.503  115.461 93.752  1.00 63.51  ? 314 ARG B N   1 
ATOM 4145 C CA  . ARG B 2 324 ? 93.857  115.805 92.493  1.00 54.02  ? 314 ARG B CA  1 
ATOM 4146 C C   . ARG B 2 324 ? 93.852  114.622 91.534  1.00 58.59  ? 314 ARG B C   1 
ATOM 4147 O O   . ARG B 2 324 ? 94.898  114.030 91.250  1.00 66.74  ? 314 ARG B O   1 
ATOM 4148 C CB  . ARG B 2 324 ? 94.575  116.994 91.859  1.00 46.81  ? 314 ARG B CB  1 
ATOM 4149 C CG  . ARG B 2 324 ? 94.203  117.262 90.416  1.00 52.23  ? 314 ARG B CG  1 
ATOM 4150 C CD  . ARG B 2 324 ? 95.095  118.344 89.831  1.00 59.39  ? 314 ARG B CD  1 
ATOM 4151 N NE  . ARG B 2 324 ? 94.817  119.654 90.406  1.00 54.12  ? 314 ARG B NE  1 
ATOM 4152 C CZ  . ARG B 2 324 ? 95.373  120.785 89.994  1.00 58.48  ? 314 ARG B CZ  1 
ATOM 4153 N NH1 . ARG B 2 324 ? 96.257  120.802 89.010  1.00 58.31  ? 314 ARG B NH1 1 
ATOM 4154 N NH2 . ARG B 2 324 ? 95.027  121.928 90.579  1.00 61.47  ? 314 ARG B NH2 1 
ATOM 4155 N N   . VAL B 2 325 ? 92.667  114.282 91.032  1.00 50.60  ? 315 VAL B N   1 
ATOM 4156 C CA  . VAL B 2 325 ? 92.530  113.281 89.977  1.00 46.67  ? 315 VAL B CA  1 
ATOM 4157 C C   . VAL B 2 325 ? 93.123  113.860 88.696  1.00 47.63  ? 315 VAL B C   1 
ATOM 4158 O O   . VAL B 2 325 ? 92.527  114.739 88.068  1.00 52.98  ? 315 VAL B O   1 
ATOM 4159 C CB  . VAL B 2 325 ? 91.068  112.868 89.779  1.00 47.86  ? 315 VAL B CB  1 
ATOM 4160 C CG1 . VAL B 2 325 ? 90.953  111.841 88.664  1.00 47.43  ? 315 VAL B CG1 1 
ATOM 4161 C CG2 . VAL B 2 325 ? 90.494  112.322 91.077  1.00 54.37  ? 315 VAL B CG2 1 
ATOM 4162 N N   . SER B 2 326 ? 94.299  113.371 88.307  1.00 44.52  ? 316 SER B N   1 
ATOM 4163 C CA  . SER B 2 326 ? 95.033  113.940 87.185  1.00 50.67  ? 316 SER B CA  1 
ATOM 4164 C C   . SER B 2 326 ? 94.692  113.304 85.844  1.00 52.43  ? 316 SER B C   1 
ATOM 4165 O O   . SER B 2 326 ? 94.920  113.934 84.805  1.00 49.68  ? 316 SER B O   1 
ATOM 4166 C CB  . SER B 2 326 ? 96.538  113.818 87.423  1.00 52.66  ? 316 SER B CB  1 
ATOM 4167 O OG  . SER B 2 326 ? 96.927  112.459 87.457  1.00 46.89  ? 316 SER B OG  1 
ATOM 4168 N N   . CYS B 2 327 ? 94.160  112.084 85.830  1.00 48.96  ? 317 CYS B N   1 
ATOM 4169 C CA  . CYS B 2 327 ? 93.930  111.396 84.568  1.00 44.75  ? 317 CYS B CA  1 
ATOM 4170 C C   . CYS B 2 327 ? 92.868  110.324 84.757  1.00 42.95  ? 317 CYS B C   1 
ATOM 4171 O O   . CYS B 2 327 ? 92.649  109.826 85.864  1.00 60.83  ? 317 CYS B O   1 
ATOM 4172 C CB  . CYS B 2 327 ? 95.223  110.778 84.027  1.00 44.50  ? 317 CYS B CB  1 
ATOM 4173 S SG  . CYS B 2 327 ? 96.049  109.663 85.182  1.00 51.42  ? 317 CYS B SG  1 
ATOM 4174 N N   . LEU B 2 328 ? 92.213  109.977 83.652  1.00 21.68  ? 318 LEU B N   1 
ATOM 4175 C CA  . LEU B 2 328 ? 91.274  108.866 83.622  1.00 18.18  ? 318 LEU B CA  1 
ATOM 4176 C C   . LEU B 2 328 ? 91.150  108.365 82.191  1.00 35.16  ? 318 LEU B C   1 
ATOM 4177 O O   . LEU B 2 328 ? 91.523  109.056 81.239  1.00 41.20  ? 318 LEU B O   1 
ATOM 4178 C CB  . LEU B 2 328 ? 89.904  109.266 84.186  1.00 25.10  ? 318 LEU B CB  1 
ATOM 4179 C CG  . LEU B 2 328 ? 89.265  110.575 83.717  1.00 34.55  ? 318 LEU B CG  1 
ATOM 4180 C CD1 . LEU B 2 328 ? 88.519  110.392 82.407  1.00 38.76  ? 318 LEU B CD1 1 
ATOM 4181 C CD2 . LEU B 2 328 ? 88.340  111.125 84.786  1.00 30.94  ? 318 LEU B CD2 1 
ATOM 4182 N N   . GLY B 2 329 ? 90.622  107.152 82.050  1.00 47.66  ? 319 GLY B N   1 
ATOM 4183 C CA  . GLY B 2 329 ? 90.422  106.573 80.736  1.00 46.14  ? 319 GLY B CA  1 
ATOM 4184 C C   . GLY B 2 329 ? 89.436  105.432 80.780  1.00 42.15  ? 319 GLY B C   1 
ATOM 4185 O O   . GLY B 2 329 ? 89.340  104.708 81.776  1.00 37.85  ? 319 GLY B O   1 
ATOM 4186 N N   . VAL B 2 330 ? 88.696  105.273 79.686  1.00 47.31  ? 320 VAL B N   1 
ATOM 4187 C CA  . VAL B 2 330 ? 87.674  104.243 79.547  1.00 44.40  ? 320 VAL B CA  1 
ATOM 4188 C C   . VAL B 2 330 ? 88.151  103.223 78.522  1.00 58.09  ? 320 VAL B C   1 
ATOM 4189 O O   . VAL B 2 330 ? 88.727  103.590 77.492  1.00 66.38  ? 320 VAL B O   1 
ATOM 4190 C CB  . VAL B 2 330 ? 86.318  104.848 79.136  1.00 45.08  ? 320 VAL B CB  1 
ATOM 4191 C CG1 . VAL B 2 330 ? 85.236  103.779 79.116  1.00 45.68  ? 320 VAL B CG1 1 
ATOM 4192 C CG2 . VAL B 2 330 ? 85.938  105.984 80.073  1.00 45.10  ? 320 VAL B CG2 1 
ATOM 4193 N N   . THR B 2 331 ? 87.918  101.944 78.811  1.00 57.20  ? 321 THR B N   1 
ATOM 4194 C CA  . THR B 2 331 ? 88.365  100.877 77.927  1.00 59.79  ? 321 THR B CA  1 
ATOM 4195 C C   . THR B 2 331 ? 87.667  100.965 76.572  1.00 66.00  ? 321 THR B C   1 
ATOM 4196 O O   . THR B 2 331 ? 86.614  101.590 76.420  1.00 66.28  ? 321 THR B O   1 
ATOM 4197 C CB  . THR B 2 331 ? 88.092  99.510  78.554  1.00 55.84  ? 321 THR B CB  1 
ATOM 4198 O OG1 . THR B 2 331 ? 86.688  99.374  78.810  1.00 57.19  ? 321 THR B OG1 1 
ATOM 4199 C CG2 . THR B 2 331 ? 88.852  99.358  79.858  1.00 60.48  ? 321 THR B CG2 1 
ATOM 4200 N N   . ASP B 2 332 ? 88.281  100.326 75.571  1.00 73.75  ? 322 ASP B N   1 
ATOM 4201 C CA  . ASP B 2 332 ? 87.711  100.341 74.227  1.00 74.85  ? 322 ASP B CA  1 
ATOM 4202 C C   . ASP B 2 332 ? 86.380  99.601  74.179  1.00 70.32  ? 322 ASP B C   1 
ATOM 4203 O O   . ASP B 2 332 ? 85.463  100.011 73.458  1.00 68.67  ? 322 ASP B O   1 
ATOM 4204 C CB  . ASP B 2 332 ? 88.699  99.732  73.232  1.00 71.88  ? 322 ASP B CB  1 
ATOM 4205 C CG  . ASP B 2 332 ? 90.065  100.387 73.289  1.00 72.87  ? 322 ASP B CG  1 
ATOM 4206 O OD1 . ASP B 2 332 ? 90.756  100.238 74.318  1.00 72.15  ? 322 ASP B OD1 1 
ATOM 4207 O OD2 . ASP B 2 332 ? 90.447  101.051 72.303  1.00 71.14  ? 322 ASP B OD2 1 
ATOM 4208 N N   . ASP B 2 333 ? 86.253  98.513  74.937  1.00 73.30  ? 323 ASP B N   1 
ATOM 4209 C CA  . ASP B 2 333 ? 84.991  97.791  75.035  1.00 77.80  ? 323 ASP B CA  1 
ATOM 4210 C C   . ASP B 2 333 ? 84.036  98.402  76.052  1.00 81.24  ? 323 ASP B C   1 
ATOM 4211 O O   . ASP B 2 333 ? 82.904  97.924  76.176  1.00 85.60  ? 323 ASP B O   1 
ATOM 4212 C CB  . ASP B 2 333 ? 85.240  96.317  75.375  1.00 73.98  ? 323 ASP B CB  1 
ATOM 4213 C CG  . ASP B 2 333 ? 86.020  96.134  76.661  1.00 75.81  ? 323 ASP B CG  1 
ATOM 4214 O OD1 . ASP B 2 333 ? 86.429  97.145  77.267  1.00 76.85  ? 323 ASP B OD1 1 
ATOM 4215 O OD2 . ASP B 2 333 ? 86.222  94.972  77.071  1.00 77.80  ? 323 ASP B OD2 1 
ATOM 4216 N N   . GLY B 2 334 ? 84.464  99.427  76.785  1.00 75.99  ? 324 GLY B N   1 
ATOM 4217 C CA  . GLY B 2 334 ? 83.602  100.076 77.750  1.00 75.06  ? 324 GLY B CA  1 
ATOM 4218 C C   . GLY B 2 334 ? 83.422  99.336  79.054  1.00 76.15  ? 324 GLY B C   1 
ATOM 4219 O O   . GLY B 2 334 ? 82.535  99.698  79.834  1.00 81.60  ? 324 GLY B O   1 
ATOM 4220 N N   . MET B 2 335 ? 84.242  98.319  79.326  1.00 64.95  ? 325 MET B N   1 
ATOM 4221 C CA  . MET B 2 335 ? 83.996  97.453  80.473  1.00 63.88  ? 325 MET B CA  1 
ATOM 4222 C C   . MET B 2 335 ? 84.358  98.137  81.786  1.00 70.90  ? 325 MET B C   1 
ATOM 4223 O O   . MET B 2 335 ? 83.671  97.948  82.796  1.00 74.32  ? 325 MET B O   1 
ATOM 4224 C CB  . MET B 2 335 ? 84.782  96.151  80.322  1.00 68.96  ? 325 MET B CB  1 
ATOM 4225 C CG  . MET B 2 335 ? 84.476  95.106  81.381  1.00 72.49  ? 325 MET B CG  1 
ATOM 4226 S SD  . MET B 2 335 ? 82.766  94.540  81.323  1.00 84.65  ? 325 MET B SD  1 
ATOM 4227 C CE  . MET B 2 335 ? 82.683  93.900  79.652  1.00 74.35  ? 325 MET B CE  1 
ATOM 4228 N N   . ALA B 2 336 ? 85.422  98.937  81.793  1.00 58.89  ? 326 ALA B N   1 
ATOM 4229 C CA  . ALA B 2 336 ? 85.911  99.524  83.031  1.00 52.58  ? 326 ALA B CA  1 
ATOM 4230 C C   . ALA B 2 336 ? 86.496  100.898 82.746  1.00 51.36  ? 326 ALA B C   1 
ATOM 4231 O O   . ALA B 2 336 ? 86.804  101.243 81.602  1.00 64.12  ? 326 ALA B O   1 
ATOM 4232 C CB  . ALA B 2 336 ? 86.957  98.627  83.701  1.00 51.84  ? 326 ALA B CB  1 
ATOM 4233 N N   . VAL B 2 337 ? 86.643  101.683 83.811  1.00 45.36  ? 327 VAL B N   1 
ATOM 4234 C CA  . VAL B 2 337 ? 87.280  102.992 83.757  1.00 50.54  ? 327 VAL B CA  1 
ATOM 4235 C C   . VAL B 2 337 ? 88.366  103.044 84.822  1.00 46.85  ? 327 VAL B C   1 
ATOM 4236 O O   . VAL B 2 337 ? 88.138  102.638 85.967  1.00 63.89  ? 327 VAL B O   1 
ATOM 4237 C CB  . VAL B 2 337 ? 86.262  104.132 83.961  1.00 49.36  ? 327 VAL B CB  1 
ATOM 4238 C CG1 . VAL B 2 337 ? 85.254  103.760 85.038  1.00 49.34  ? 327 VAL B CG1 1 
ATOM 4239 C CG2 . VAL B 2 337 ? 86.973  105.430 84.313  1.00 39.66  ? 327 VAL B CG2 1 
ATOM 4240 N N   . ALA B 2 338 ? 89.543  103.534 84.446  1.00 20.89  ? 328 ALA B N   1 
ATOM 4241 C CA  . ALA B 2 338 ? 90.645  103.735 85.374  1.00 23.83  ? 328 ALA B CA  1 
ATOM 4242 C C   . ALA B 2 338 ? 90.799  105.224 85.648  1.00 34.30  ? 328 ALA B C   1 
ATOM 4243 O O   . ALA B 2 338 ? 90.676  106.044 84.736  1.00 48.38  ? 328 ALA B O   1 
ATOM 4244 C CB  . ALA B 2 338 ? 91.952  103.168 84.817  1.00 30.86  ? 328 ALA B CB  1 
ATOM 4245 N N   . THR B 2 339 ? 91.064  105.570 86.905  1.00 43.67  ? 329 THR B N   1 
ATOM 4246 C CA  . THR B 2 339 ? 91.332  106.947 87.300  1.00 28.78  ? 329 THR B CA  1 
ATOM 4247 C C   . THR B 2 339 ? 92.676  107.018 88.008  1.00 26.00  ? 329 THR B C   1 
ATOM 4248 O O   . THR B 2 339 ? 92.922  106.267 88.958  1.00 37.39  ? 329 THR B O   1 
ATOM 4249 C CB  . THR B 2 339 ? 90.228  107.488 88.214  1.00 35.34  ? 329 THR B CB  1 
ATOM 4250 O OG1 . THR B 2 339 ? 90.105  106.649 89.369  1.00 55.16  ? 329 THR B OG1 1 
ATOM 4251 C CG2 . THR B 2 339 ? 88.896  107.530 87.483  1.00 44.38  ? 329 THR B CG2 1 
ATOM 4252 N N   . GLY B 2 340 ? 93.539  107.921 87.547  1.00 32.98  ? 330 GLY B N   1 
ATOM 4253 C CA  . GLY B 2 340 ? 94.799  108.209 88.206  1.00 37.09  ? 330 GLY B CA  1 
ATOM 4254 C C   . GLY B 2 340 ? 94.743  109.542 88.926  1.00 44.82  ? 330 GLY B C   1 
ATOM 4255 O O   . GLY B 2 340 ? 93.967  110.428 88.561  1.00 51.95  ? 330 GLY B O   1 
ATOM 4256 N N   . SER B 2 341 ? 95.572  109.680 89.957  1.00 46.44  ? 331 SER B N   1 
ATOM 4257 C CA  . SER B 2 341 ? 95.508  110.832 90.842  1.00 47.16  ? 331 SER B CA  1 
ATOM 4258 C C   . SER B 2 341 ? 96.899  111.125 91.382  1.00 52.16  ? 331 SER B C   1 
ATOM 4259 O O   . SER B 2 341 ? 97.798  110.282 91.336  1.00 52.76  ? 331 SER B O   1 
ATOM 4260 C CB  . SER B 2 341 ? 94.519  110.612 91.991  1.00 48.31  ? 331 SER B CB  1 
ATOM 4261 O OG  . SER B 2 341 ? 94.554  111.693 92.907  1.00 54.88  ? 331 SER B OG  1 
ATOM 4262 N N   . TRP B 2 342 ? 97.063  112.343 91.897  1.00 47.50  ? 332 TRP B N   1 
ATOM 4263 C CA  . TRP B 2 342 ? 98.303  112.748 92.545  1.00 40.81  ? 332 TRP B CA  1 
ATOM 4264 C C   . TRP B 2 342 ? 98.572  112.005 93.849  1.00 50.28  ? 332 TRP B C   1 
ATOM 4265 O O   . TRP B 2 342 ? 99.676  112.126 94.390  1.00 52.83  ? 332 TRP B O   1 
ATOM 4266 C CB  . TRP B 2 342 ? 98.292  114.256 92.796  1.00 37.28  ? 332 TRP B CB  1 
ATOM 4267 C CG  . TRP B 2 342 ? 98.422  115.062 91.542  1.00 37.53  ? 332 TRP B CG  1 
ATOM 4268 C CD1 . TRP B 2 342 ? 98.543  114.585 90.270  1.00 50.77  ? 332 TRP B CD1 1 
ATOM 4269 C CD2 . TRP B 2 342 ? 98.470  116.489 91.441  1.00 41.83  ? 332 TRP B CD2 1 
ATOM 4270 N NE1 . TRP B 2 342 ? 98.650  115.626 89.381  1.00 53.31  ? 332 TRP B NE1 1 
ATOM 4271 C CE2 . TRP B 2 342 ? 98.609  116.806 90.075  1.00 47.02  ? 332 TRP B CE2 1 
ATOM 4272 C CE3 . TRP B 2 342 ? 98.403  117.528 92.371  1.00 46.75  ? 332 TRP B CE3 1 
ATOM 4273 C CZ2 . TRP B 2 342 ? 98.683  118.118 89.618  1.00 47.37  ? 332 TRP B CZ2 1 
ATOM 4274 C CZ3 . TRP B 2 342 ? 98.477  118.829 91.916  1.00 53.99  ? 332 TRP B CZ3 1 
ATOM 4275 C CH2 . TRP B 2 342 ? 98.615  119.113 90.552  1.00 53.12  ? 332 TRP B CH2 1 
ATOM 4276 N N   . ASP B 2 343 ? 97.604  111.251 94.369  1.00 52.84  ? 333 ASP B N   1 
ATOM 4277 C CA  . ASP B 2 343 ? 97.837  110.456 95.569  1.00 51.90  ? 333 ASP B CA  1 
ATOM 4278 C C   . ASP B 2 343 ? 98.563  109.148 95.281  1.00 52.02  ? 333 ASP B C   1 
ATOM 4279 O O   . ASP B 2 343 ? 98.689  108.321 96.191  1.00 51.06  ? 333 ASP B O   1 
ATOM 4280 C CB  . ASP B 2 343 ? 96.513  110.166 96.284  1.00 56.81  ? 333 ASP B CB  1 
ATOM 4281 C CG  . ASP B 2 343 ? 95.613  109.225 95.503  1.00 56.18  ? 333 ASP B CG  1 
ATOM 4282 O OD1 . ASP B 2 343 ? 95.866  108.997 94.302  1.00 51.14  ? 333 ASP B OD1 1 
ATOM 4283 O OD2 . ASP B 2 343 ? 94.651  108.701 96.098  1.00 52.72  ? 333 ASP B OD2 1 
ATOM 4284 N N   . SER B 2 344 ? 98.996  108.937 94.033  1.00 52.76  ? 334 SER B N   1 
ATOM 4285 C CA  . SER B 2 344 ? 99.838  107.820 93.603  1.00 49.11  ? 334 SER B CA  1 
ATOM 4286 C C   . SER B 2 344 ? 99.079  106.508 93.460  1.00 43.54  ? 334 SER B C   1 
ATOM 4287 O O   . SER B 2 344 ? 99.701  105.440 93.437  1.00 48.23  ? 334 SER B O   1 
ATOM 4288 C CB  . SER B 2 344 ? 101.039 107.615 94.536  1.00 45.30  ? 334 SER B CB  1 
ATOM 4289 O OG  . SER B 2 344 ? 100.638 107.063 95.778  1.00 53.25  ? 334 SER B OG  1 
ATOM 4290 N N   . PHE B 2 345 ? 97.754  106.542 93.350  1.00 36.59  ? 335 PHE B N   1 
ATOM 4291 C CA  . PHE B 2 345 ? 96.959  105.332 93.207  1.00 32.46  ? 335 PHE B CA  1 
ATOM 4292 C C   . PHE B 2 345 ? 96.159  105.361 91.912  1.00 39.64  ? 335 PHE B C   1 
ATOM 4293 O O   . PHE B 2 345 ? 95.766  106.426 91.426  1.00 53.60  ? 335 PHE B O   1 
ATOM 4294 C CB  . PHE B 2 345 ? 95.996  105.154 94.390  1.00 43.98  ? 335 PHE B CB  1 
ATOM 4295 C CG  . PHE B 2 345 ? 96.676  105.102 95.726  1.00 49.30  ? 335 PHE B CG  1 
ATOM 4296 C CD1 . PHE B 2 345 ? 97.910  104.490 95.871  1.00 45.53  ? 335 PHE B CD1 1 
ATOM 4297 C CD2 . PHE B 2 345 ? 96.078  105.664 96.840  1.00 48.42  ? 335 PHE B CD2 1 
ATOM 4298 C CE1 . PHE B 2 345 ? 98.535  104.444 97.100  1.00 44.42  ? 335 PHE B CE1 1 
ATOM 4299 C CE2 . PHE B 2 345 ? 96.697  105.619 98.072  1.00 50.71  ? 335 PHE B CE2 1 
ATOM 4300 C CZ  . PHE B 2 345 ? 97.927  105.009 98.202  1.00 48.38  ? 335 PHE B CZ  1 
ATOM 4301 N N   . LEU B 2 346 ? 95.929  104.174 91.357  1.00 42.32  ? 336 LEU B N   1 
ATOM 4302 C CA  . LEU B 2 346 ? 95.003  103.975 90.253  1.00 41.76  ? 336 LEU B CA  1 
ATOM 4303 C C   . LEU B 2 346 ? 93.848  103.104 90.727  1.00 46.80  ? 336 LEU B C   1 
ATOM 4304 O O   . LEU B 2 346 ? 94.053  102.135 91.464  1.00 44.08  ? 336 LEU B O   1 
ATOM 4305 C CB  . LEU B 2 346 ? 95.696  103.309 89.063  1.00 39.30  ? 336 LEU B CB  1 
ATOM 4306 C CG  . LEU B 2 346 ? 96.490  104.180 88.092  1.00 33.66  ? 336 LEU B CG  1 
ATOM 4307 C CD1 . LEU B 2 346 ? 97.501  103.326 87.348  1.00 37.57  ? 336 LEU B CD1 1 
ATOM 4308 C CD2 . LEU B 2 346 ? 95.559  104.871 87.115  1.00 41.10  ? 336 LEU B CD2 1 
ATOM 4309 N N   . LYS B 2 347 ? 92.637  103.444 90.298  1.00 42.61  ? 337 LYS B N   1 
ATOM 4310 C CA  . LYS B 2 347 ? 91.446  102.705 90.688  1.00 42.09  ? 337 LYS B CA  1 
ATOM 4311 C C   . LYS B 2 347 ? 90.632  102.339 89.458  1.00 38.35  ? 337 LYS B C   1 
ATOM 4312 O O   . LYS B 2 347 ? 90.510  103.132 88.520  1.00 48.71  ? 337 LYS B O   1 
ATOM 4313 C CB  . LYS B 2 347 ? 90.592  103.499 91.680  1.00 39.75  ? 337 LYS B CB  1 
ATOM 4314 C CG  . LYS B 2 347 ? 91.263  103.672 93.032  1.00 49.76  ? 337 LYS B CG  1 
ATOM 4315 C CD  . LYS B 2 347 ? 90.280  104.102 94.104  1.00 44.96  ? 337 LYS B CD  1 
ATOM 4316 C CE  . LYS B 2 347 ? 90.902  103.969 95.485  1.00 41.69  ? 337 LYS B CE  1 
ATOM 4317 N NZ  . LYS B 2 347 ? 89.977  104.405 96.563  1.00 49.87  ? 337 LYS B NZ  1 
ATOM 4318 N N   . ILE B 2 348 ? 90.072  101.133 89.477  1.00 42.56  ? 338 ILE B N   1 
ATOM 4319 C CA  . ILE B 2 348 ? 89.247  100.610 88.395  1.00 36.55  ? 338 ILE B CA  1 
ATOM 4320 C C   . ILE B 2 348 ? 87.806  100.569 88.881  1.00 36.57  ? 338 ILE B C   1 
ATOM 4321 O O   . ILE B 2 348 ? 87.526  100.037 89.963  1.00 57.57  ? 338 ILE B O   1 
ATOM 4322 C CB  . ILE B 2 348 ? 89.717  99.212  87.957  1.00 42.92  ? 338 ILE B CB  1 
ATOM 4323 C CG1 . ILE B 2 348 ? 91.242  99.172  87.843  1.00 31.59  ? 338 ILE B CG1 1 
ATOM 4324 C CG2 . ILE B 2 348 ? 89.078  98.822  86.638  1.00 49.36  ? 338 ILE B CG2 1 
ATOM 4325 C CD1 . ILE B 2 348 ? 91.805  100.096 86.794  1.00 40.53  ? 338 ILE B CD1 1 
ATOM 4326 N N   . TRP B 2 349 ? 86.896  101.132 88.092  1.00 30.93  ? 339 TRP B N   1 
ATOM 4327 C CA  . TRP B 2 349 ? 85.503  101.272 88.489  1.00 46.74  ? 339 TRP B CA  1 
ATOM 4328 C C   . TRP B 2 349 ? 84.601  100.593 87.470  1.00 58.88  ? 339 TRP B C   1 
ATOM 4329 O O   . TRP B 2 349 ? 84.850  100.660 86.262  1.00 68.56  ? 339 TRP B O   1 
ATOM 4330 C CB  . TRP B 2 349 ? 85.114  102.750 88.621  1.00 50.42  ? 339 TRP B CB  1 
ATOM 4331 C CG  . TRP B 2 349 ? 86.104  103.576 89.390  1.00 54.26  ? 339 TRP B CG  1 
ATOM 4332 C CD1 . TRP B 2 349 ? 87.298  104.058 88.934  1.00 58.44  ? 339 TRP B CD1 1 
ATOM 4333 C CD2 . TRP B 2 349 ? 85.979  104.029 90.743  1.00 58.72  ? 339 TRP B CD2 1 
ATOM 4334 N NE1 . TRP B 2 349 ? 87.928  104.774 89.922  1.00 54.83  ? 339 TRP B NE1 1 
ATOM 4335 C CE2 . TRP B 2 349 ? 87.139  104.773 91.042  1.00 53.70  ? 339 TRP B CE2 1 
ATOM 4336 C CE3 . TRP B 2 349 ? 85.002  103.876 91.732  1.00 61.91  ? 339 TRP B CE3 1 
ATOM 4337 C CZ2 . TRP B 2 349 ? 87.348  105.362 92.286  1.00 53.86  ? 339 TRP B CZ2 1 
ATOM 4338 C CZ3 . TRP B 2 349 ? 85.212  104.462 92.967  1.00 63.75  ? 339 TRP B CZ3 1 
ATOM 4339 C CH2 . TRP B 2 349 ? 86.375  105.196 93.233  1.00 57.22  ? 339 TRP B CH2 1 
ATOM 4340 N N   . ASN B 2 350 ? 83.549  99.947  87.967  1.00 70.80  ? 340 ASN B N   1 
ATOM 4341 C CA  . ASN B 2 350 ? 82.414  99.534  87.153  1.00 69.65  ? 340 ASN B CA  1 
ATOM 4342 C C   . ASN B 2 350 ? 81.236  99.274  88.081  1.00 74.40  ? 340 ASN B C   1 
ATOM 4343 O O   . ASN B 2 350 ? 81.392  99.179  89.300  1.00 75.99  ? 340 ASN B O   1 
ATOM 4344 C CB  . ASN B 2 350 ? 82.739  98.299  86.307  1.00 61.27  ? 340 ASN B CB  1 
ATOM 4345 C CG  . ASN B 2 350 ? 83.377  97.189  87.115  1.00 64.19  ? 340 ASN B CG  1 
ATOM 4346 O OD1 . ASN B 2 350 ? 82.691  96.430  87.798  1.00 68.42  ? 340 ASN B OD1 1 
ATOM 4347 N ND2 . ASN B 2 350 ? 84.698  97.084  87.034  1.00 64.24  ? 340 ASN B ND2 1 
ATOM 4348 N N   . GLY B 2 351 ? 80.047  99.161  87.487  1.00 88.86  ? 341 GLY B N   1 
ATOM 4349 C CA  . GLY B 2 351 ? 78.837  98.962  88.254  1.00 88.44  ? 341 GLY B CA  1 
ATOM 4350 C C   . GLY B 2 351 ? 78.557  97.495  88.527  1.00 92.70  ? 341 GLY B C   1 
ATOM 4351 O O   . GLY B 2 351 ? 79.284  96.596  88.106  1.00 91.64  ? 341 GLY B O   1 
ATOM 4352 N N   . SER B 2 352 ? 77.466  97.260  89.253  1.00 108.52 ? 342 SER B N   1 
ATOM 4353 C CA  . SER B 2 352 ? 77.012  95.913  89.562  1.00 104.86 ? 342 SER B CA  1 
ATOM 4354 C C   . SER B 2 352 ? 75.507  95.824  89.361  1.00 105.69 ? 342 SER B C   1 
ATOM 4355 O O   . SER B 2 352 ? 74.779  96.800  89.558  1.00 105.53 ? 342 SER B O   1 
ATOM 4356 C CB  . SER B 2 352 ? 77.374  95.509  90.997  1.00 102.77 ? 342 SER B CB  1 
ATOM 4357 O OG  . SER B 2 352 ? 76.791  96.392  91.939  1.00 102.58 ? 342 SER B OG  1 
ATOM 4358 N N   . SER B 2 353 ? 75.051  94.640  88.964  1.00 115.04 ? 343 SER B N   1 
ATOM 4359 C CA  . SER B 2 353 ? 73.631  94.397  88.739  1.00 115.97 ? 343 SER B CA  1 
ATOM 4360 C C   . SER B 2 353 ? 72.849  94.454  90.048  1.00 114.92 ? 343 SER B C   1 
ATOM 4361 O O   . SER B 2 353 ? 72.319  95.501  90.421  1.00 113.85 ? 343 SER B O   1 
ATOM 4362 C CB  . SER B 2 353 ? 73.422  93.043  88.060  1.00 113.32 ? 343 SER B CB  1 
ATOM 4363 O OG  . SER B 2 353 ? 74.094  92.990  86.813  1.00 111.03 ? 343 SER B OG  1 
ATOM 4364 N N   . THR C 3 6   ? 108.896 143.420 59.377  1.00 222.72 ? 6   THR C N   1 
ATOM 4365 C CA  . THR C 3 6   ? 107.756 143.006 58.567  1.00 222.91 ? 6   THR C CA  1 
ATOM 4366 C C   . THR C 3 6   ? 107.176 141.689 59.073  1.00 222.65 ? 6   THR C C   1 
ATOM 4367 O O   . THR C 3 6   ? 106.546 140.946 58.319  1.00 222.44 ? 6   THR C O   1 
ATOM 4368 C CB  . THR C 3 6   ? 108.142 142.852 57.084  1.00 222.86 ? 6   THR C CB  1 
ATOM 4369 O OG1 . THR C 3 6   ? 109.178 141.870 56.956  1.00 223.35 ? 6   THR C OG1 1 
ATOM 4370 C CG2 . THR C 3 6   ? 108.634 144.177 56.521  1.00 222.27 ? 6   THR C CG2 1 
ATOM 4371 N N   . ALA C 3 7   ? 107.399 141.402 60.356  1.00 218.45 ? 7   ALA C N   1 
ATOM 4372 C CA  . ALA C 3 7   ? 106.853 140.184 60.946  1.00 218.39 ? 7   ALA C CA  1 
ATOM 4373 C C   . ALA C 3 7   ? 105.352 140.305 61.186  1.00 218.66 ? 7   ALA C C   1 
ATOM 4374 O O   . ALA C 3 7   ? 104.599 139.359 60.929  1.00 218.32 ? 7   ALA C O   1 
ATOM 4375 C CB  . ALA C 3 7   ? 107.581 139.859 62.249  1.00 217.97 ? 7   ALA C CB  1 
ATOM 4376 N N   . SER C 3 8   ? 104.901 141.459 61.686  1.00 215.61 ? 8   SER C N   1 
ATOM 4377 C CA  . SER C 3 8   ? 103.481 141.637 61.975  1.00 215.10 ? 8   SER C CA  1 
ATOM 4378 C C   . SER C 3 8   ? 102.639 141.609 60.705  1.00 215.57 ? 8   SER C C   1 
ATOM 4379 O O   . SER C 3 8   ? 101.558 141.009 60.686  1.00 215.43 ? 8   SER C O   1 
ATOM 4380 C CB  . SER C 3 8   ? 103.263 142.947 62.733  1.00 213.94 ? 8   SER C CB  1 
ATOM 4381 O OG  . SER C 3 8   ? 103.971 142.951 63.960  1.00 213.78 ? 8   SER C OG  1 
ATOM 4382 N N   . ILE C 3 9   ? 103.111 142.255 59.637  1.00 215.65 ? 9   ILE C N   1 
ATOM 4383 C CA  . ILE C 3 9   ? 102.340 142.294 58.397  1.00 215.14 ? 9   ILE C CA  1 
ATOM 4384 C C   . ILE C 3 9   ? 102.261 140.906 57.770  1.00 215.19 ? 9   ILE C C   1 
ATOM 4385 O O   . ILE C 3 9   ? 101.238 140.532 57.183  1.00 215.36 ? 9   ILE C O   1 
ATOM 4386 C CB  . ILE C 3 9   ? 102.934 143.335 57.428  1.00 213.76 ? 9   ILE C CB  1 
ATOM 4387 C CG1 . ILE C 3 9   ? 102.090 143.432 56.155  1.00 213.15 ? 9   ILE C CG1 1 
ATOM 4388 C CG2 . ILE C 3 9   ? 104.384 143.017 57.096  1.00 213.64 ? 9   ILE C CG2 1 
ATOM 4389 C CD1 . ILE C 3 9   ? 100.703 143.984 56.386  1.00 214.07 ? 9   ILE C CD1 1 
ATOM 4390 N N   . ALA C 3 10  ? 103.334 140.118 57.886  1.00 212.22 ? 10  ALA C N   1 
ATOM 4391 C CA  . ALA C 3 10  ? 103.312 138.752 57.372  1.00 211.49 ? 10  ALA C CA  1 
ATOM 4392 C C   . ALA C 3 10  ? 102.352 137.874 58.166  1.00 211.36 ? 10  ALA C C   1 
ATOM 4393 O O   . ALA C 3 10  ? 101.640 137.045 57.589  1.00 211.41 ? 10  ALA C O   1 
ATOM 4394 C CB  . ALA C 3 10  ? 104.721 138.162 57.391  1.00 211.26 ? 10  ALA C CB  1 
ATOM 4395 N N   . GLN C 3 11  ? 102.323 138.039 59.491  1.00 203.83 ? 11  GLN C N   1 
ATOM 4396 C CA  . GLN C 3 11  ? 101.401 137.263 60.314  1.00 203.29 ? 11  GLN C CA  1 
ATOM 4397 C C   . GLN C 3 11  ? 99.952  137.642 60.035  1.00 203.11 ? 11  GLN C C   1 
ATOM 4398 O O   . GLN C 3 11  ? 99.061  136.784 60.078  1.00 202.14 ? 11  GLN C O   1 
ATOM 4399 C CB  . GLN C 3 11  ? 101.732 137.456 61.794  1.00 203.13 ? 11  GLN C CB  1 
ATOM 4400 C CG  . GLN C 3 11  ? 100.862 136.643 62.739  1.00 202.49 ? 11  GLN C CG  1 
ATOM 4401 C CD  . GLN C 3 11  ? 101.197 136.888 64.197  1.00 202.80 ? 11  GLN C CD  1 
ATOM 4402 O OE1 . GLN C 3 11  ? 102.086 137.677 64.518  1.00 201.97 ? 11  GLN C OE1 1 
ATOM 4403 N NE2 . GLN C 3 11  ? 100.483 136.212 65.090  1.00 203.32 ? 11  GLN C NE2 1 
ATOM 4404 N N   . ALA C 3 12  ? 99.694  138.922 59.752  1.00 203.42 ? 12  ALA C N   1 
ATOM 4405 C CA  . ALA C 3 12  ? 98.327  139.360 59.488  1.00 202.93 ? 12  ALA C CA  1 
ATOM 4406 C C   . ALA C 3 12  ? 97.762  138.692 58.240  1.00 203.02 ? 12  ALA C C   1 
ATOM 4407 O O   . ALA C 3 12  ? 96.593  138.291 58.218  1.00 202.57 ? 12  ALA C O   1 
ATOM 4408 C CB  . ALA C 3 12  ? 98.280  140.881 59.352  1.00 202.82 ? 12  ALA C CB  1 
ATOM 4409 N N   . ARG C 3 13  ? 98.577  138.569 57.189  1.00 201.32 ? 13  ARG C N   1 
ATOM 4410 C CA  . ARG C 3 13  ? 98.117  137.912 55.968  1.00 200.34 ? 13  ARG C CA  1 
ATOM 4411 C C   . ARG C 3 13  ? 97.787  136.446 56.220  1.00 200.07 ? 13  ARG C C   1 
ATOM 4412 O O   . ARG C 3 13  ? 96.795  135.926 55.696  1.00 199.77 ? 13  ARG C O   1 
ATOM 4413 C CB  . ARG C 3 13  ? 99.171  138.046 54.870  1.00 200.04 ? 13  ARG C CB  1 
ATOM 4414 C CG  . ARG C 3 13  ? 99.481  139.481 54.479  1.00 200.05 ? 13  ARG C CG  1 
ATOM 4415 C CD  . ARG C 3 13  ? 100.525 139.541 53.377  1.00 200.46 ? 13  ARG C CD  1 
ATOM 4416 N NE  . ARG C 3 13  ? 100.817 140.912 52.976  1.00 201.15 ? 13  ARG C NE  1 
ATOM 4417 C CZ  . ARG C 3 13  ? 100.176 141.564 52.016  1.00 200.72 ? 13  ARG C CZ  1 
ATOM 4418 N NH1 . ARG C 3 13  ? 99.196  140.998 51.331  1.00 200.15 ? 13  ARG C NH1 1 
ATOM 4419 N NH2 . ARG C 3 13  ? 100.528 142.816 51.735  1.00 200.84 ? 13  ARG C NH2 1 
ATOM 4420 N N   . LYS C 3 14  ? 98.613  135.763 57.016  1.00 190.12 ? 14  LYS C N   1 
ATOM 4421 C CA  . LYS C 3 14  ? 98.373  134.352 57.303  1.00 189.42 ? 14  LYS C CA  1 
ATOM 4422 C C   . LYS C 3 14  ? 97.098  134.159 58.115  1.00 189.41 ? 14  LYS C C   1 
ATOM 4423 O O   . LYS C 3 14  ? 96.321  133.234 57.849  1.00 189.92 ? 14  LYS C O   1 
ATOM 4424 C CB  . LYS C 3 14  ? 99.573  133.755 58.037  1.00 189.22 ? 14  LYS C CB  1 
ATOM 4425 C CG  . LYS C 3 14  ? 99.485  132.254 58.256  1.00 189.53 ? 14  LYS C CG  1 
ATOM 4426 C CD  . LYS C 3 14  ? 100.755 131.715 58.895  1.00 189.65 ? 14  LYS C CD  1 
ATOM 4427 C CE  . LYS C 3 14  ? 100.693 130.205 59.059  1.00 188.36 ? 14  LYS C CE  1 
ATOM 4428 N NZ  . LYS C 3 14  ? 101.943 129.661 59.657  1.00 186.92 ? 14  LYS C NZ  1 
ATOM 4429 N N   . LEU C 3 15  ? 96.871  135.015 59.114  1.00 184.42 ? 15  LEU C N   1 
ATOM 4430 C CA  . LEU C 3 15  ? 95.670  134.892 59.936  1.00 184.24 ? 15  LEU C CA  1 
ATOM 4431 C C   . LEU C 3 15  ? 94.409  135.141 59.116  1.00 184.29 ? 15  LEU C C   1 
ATOM 4432 O O   . LEU C 3 15  ? 93.405  134.439 59.283  1.00 183.33 ? 15  LEU C O   1 
ATOM 4433 C CB  . LEU C 3 15  ? 95.742  135.860 61.117  1.00 184.43 ? 15  LEU C CB  1 
ATOM 4434 C CG  . LEU C 3 15  ? 94.540  135.867 62.063  1.00 183.83 ? 15  LEU C CG  1 
ATOM 4435 C CD1 . LEU C 3 15  ? 94.336  134.493 62.684  1.00 184.18 ? 15  LEU C CD1 1 
ATOM 4436 C CD2 . LEU C 3 15  ? 94.707  136.928 63.140  1.00 183.05 ? 15  LEU C CD2 1 
ATOM 4437 N N   . VAL C 3 16  ? 94.441  136.136 58.228  1.00 189.45 ? 16  VAL C N   1 
ATOM 4438 C CA  . VAL C 3 16  ? 93.294  136.392 57.359  1.00 189.54 ? 16  VAL C CA  1 
ATOM 4439 C C   . VAL C 3 16  ? 93.069  135.218 56.415  1.00 188.69 ? 16  VAL C C   1 
ATOM 4440 O O   . VAL C 3 16  ? 91.928  134.794 56.189  1.00 188.23 ? 16  VAL C O   1 
ATOM 4441 C CB  . VAL C 3 16  ? 93.489  137.712 56.590  1.00 189.29 ? 16  VAL C CB  1 
ATOM 4442 C CG1 . VAL C 3 16  ? 92.399  137.886 55.542  1.00 188.35 ? 16  VAL C CG1 1 
ATOM 4443 C CG2 . VAL C 3 16  ? 93.493  138.889 57.553  1.00 189.25 ? 16  VAL C CG2 1 
ATOM 4444 N N   . GLU C 3 17  ? 94.150  134.671 55.853  1.00 179.10 ? 17  GLU C N   1 
ATOM 4445 C CA  . GLU C 3 17  ? 94.016  133.550 54.928  1.00 177.89 ? 17  GLU C CA  1 
ATOM 4446 C C   . GLU C 3 17  ? 93.464  132.317 55.633  1.00 177.94 ? 17  GLU C C   1 
ATOM 4447 O O   . GLU C 3 17  ? 92.679  131.559 55.050  1.00 177.05 ? 17  GLU C O   1 
ATOM 4448 C CB  . GLU C 3 17  ? 95.365  133.242 54.279  1.00 176.93 ? 17  GLU C CB  1 
ATOM 4449 C CG  . GLU C 3 17  ? 95.320  132.136 53.235  1.00 176.86 ? 17  GLU C CG  1 
ATOM 4450 C CD  . GLU C 3 17  ? 94.564  132.539 51.983  1.00 177.71 ? 17  GLU C CD  1 
ATOM 4451 O OE1 . GLU C 3 17  ? 94.438  133.755 51.726  1.00 179.15 ? 17  GLU C OE1 1 
ATOM 4452 O OE2 . GLU C 3 17  ? 94.096  131.639 51.255  1.00 177.39 ? 17  GLU C OE2 1 
ATOM 4453 N N   . GLN C 3 18  ? 93.866  132.098 56.887  1.00 172.31 ? 18  GLN C N   1 
ATOM 4454 C CA  . GLN C 3 18  ? 93.350  130.959 57.640  1.00 171.21 ? 18  GLN C CA  1 
ATOM 4455 C C   . GLN C 3 18  ? 91.856  131.103 57.906  1.00 171.46 ? 18  GLN C C   1 
ATOM 4456 O O   . GLN C 3 18  ? 91.103  130.129 57.792  1.00 172.06 ? 18  GLN C O   1 
ATOM 4457 C CB  . GLN C 3 18  ? 94.119  130.808 58.952  1.00 170.73 ? 18  GLN C CB  1 
ATOM 4458 C CG  . GLN C 3 18  ? 93.599  129.704 59.860  1.00 170.44 ? 18  GLN C CG  1 
ATOM 4459 C CD  . GLN C 3 18  ? 93.753  128.323 59.251  1.00 170.62 ? 18  GLN C CD  1 
ATOM 4460 O OE1 . GLN C 3 18  ? 94.645  128.087 58.436  1.00 170.29 ? 18  GLN C OE1 1 
ATOM 4461 N NE2 . GLN C 3 18  ? 92.882  127.402 59.645  1.00 170.69 ? 18  GLN C NE2 1 
ATOM 4462 N N   . LEU C 3 19  ? 91.411  132.310 58.267  1.00 175.71 ? 19  LEU C N   1 
ATOM 4463 C CA  . LEU C 3 19  ? 89.996  132.524 58.554  1.00 175.49 ? 19  LEU C CA  1 
ATOM 4464 C C   . LEU C 3 19  ? 89.129  132.336 57.315  1.00 176.24 ? 19  LEU C C   1 
ATOM 4465 O O   . LEU C 3 19  ? 87.949  131.990 57.436  1.00 175.26 ? 19  LEU C O   1 
ATOM 4466 C CB  . LEU C 3 19  ? 89.783  133.920 59.141  1.00 175.80 ? 19  LEU C CB  1 
ATOM 4467 C CG  . LEU C 3 19  ? 90.393  134.183 60.519  1.00 175.20 ? 19  LEU C CG  1 
ATOM 4468 C CD1 . LEU C 3 19  ? 90.123  135.613 60.962  1.00 175.40 ? 19  LEU C CD1 1 
ATOM 4469 C CD2 . LEU C 3 19  ? 89.861  133.191 61.541  1.00 175.42 ? 19  LEU C CD2 1 
ATOM 4470 N N   . LYS C 3 20  ? 89.689  132.560 56.124  1.00 177.75 ? 20  LYS C N   1 
ATOM 4471 C CA  . LYS C 3 20  ? 88.934  132.319 54.898  1.00 177.11 ? 20  LYS C CA  1 
ATOM 4472 C C   . LYS C 3 20  ? 88.621  130.838 54.721  1.00 176.67 ? 20  LYS C C   1 
ATOM 4473 O O   . LYS C 3 20  ? 87.510  130.478 54.315  1.00 176.80 ? 20  LYS C O   1 
ATOM 4474 C CB  . LYS C 3 20  ? 89.706  132.853 53.691  1.00 175.77 ? 20  LYS C CB  1 
ATOM 4475 C CG  . LYS C 3 20  ? 89.880  134.362 53.685  1.00 176.55 ? 20  LYS C CG  1 
ATOM 4476 C CD  . LYS C 3 20  ? 90.601  134.830 52.433  1.00 177.06 ? 20  LYS C CD  1 
ATOM 4477 C CE  . LYS C 3 20  ? 90.745  136.343 52.411  1.00 175.94 ? 20  LYS C CE  1 
ATOM 4478 N NZ  . LYS C 3 20  ? 91.439  136.816 51.181  1.00 175.23 ? 20  LYS C NZ  1 
ATOM 4479 N N   . MET C 3 21  ? 89.588  129.966 55.016  1.00 167.26 ? 21  MET C N   1 
ATOM 4480 C CA  . MET C 3 21  ? 89.353  128.532 54.882  1.00 166.06 ? 21  MET C CA  1 
ATOM 4481 C C   . MET C 3 21  ? 88.294  128.054 55.867  1.00 165.66 ? 21  MET C C   1 
ATOM 4482 O O   . MET C 3 21  ? 87.443  127.226 55.520  1.00 165.04 ? 21  MET C O   1 
ATOM 4483 C CB  . MET C 3 21  ? 90.660  127.766 55.081  1.00 165.49 ? 21  MET C CB  1 
ATOM 4484 C CG  . MET C 3 21  ? 91.750  128.129 54.086  1.00 165.74 ? 21  MET C CG  1 
ATOM 4485 S SD  . MET C 3 21  ? 91.264  127.810 52.379  1.00 167.90 ? 21  MET C SD  1 
ATOM 4486 C CE  . MET C 3 21  ? 90.955  126.047 52.439  1.00 165.96 ? 21  MET C CE  1 
ATOM 4487 N N   . GLU C 3 22  ? 88.331  128.562 57.101  1.00 162.92 ? 22  GLU C N   1 
ATOM 4488 C CA  . GLU C 3 22  ? 87.369  128.132 58.109  1.00 163.55 ? 22  GLU C CA  1 
ATOM 4489 C C   . GLU C 3 22  ? 85.977  128.692 57.839  1.00 164.44 ? 22  GLU C C   1 
ATOM 4490 O O   . GLU C 3 22  ? 84.979  128.085 58.243  1.00 164.70 ? 22  GLU C O   1 
ATOM 4491 C CB  . GLU C 3 22  ? 87.847  128.546 59.500  1.00 163.13 ? 22  GLU C CB  1 
ATOM 4492 C CG  . GLU C 3 22  ? 89.163  127.910 59.917  1.00 162.02 ? 22  GLU C CG  1 
ATOM 4493 C CD  . GLU C 3 22  ? 89.595  128.319 61.312  1.00 162.43 ? 22  GLU C CD  1 
ATOM 4494 O OE1 . GLU C 3 22  ? 88.911  129.166 61.923  1.00 165.40 ? 22  GLU C OE1 1 
ATOM 4495 O OE2 . GLU C 3 22  ? 90.618  127.792 61.797  1.00 160.75 ? 22  GLU C OE2 1 
ATOM 4496 N N   . ALA C 3 23  ? 85.888  129.841 57.167  1.00 173.08 ? 23  ALA C N   1 
ATOM 4497 C CA  . ALA C 3 23  ? 84.599  130.462 56.892  1.00 173.10 ? 23  ALA C CA  1 
ATOM 4498 C C   . ALA C 3 23  ? 83.892  129.867 55.681  1.00 173.81 ? 23  ALA C C   1 
ATOM 4499 O O   . ALA C 3 23  ? 82.722  130.189 55.450  1.00 174.04 ? 23  ALA C O   1 
ATOM 4500 C CB  . ALA C 3 23  ? 84.773  131.969 56.690  1.00 171.76 ? 23  ALA C CB  1 
ATOM 4501 N N   . ASN C 3 24  ? 84.563  129.016 54.907  1.00 174.52 ? 24  ASN C N   1 
ATOM 4502 C CA  . ASN C 3 24  ? 83.998  128.453 53.688  1.00 174.73 ? 24  ASN C CA  1 
ATOM 4503 C C   . ASN C 3 24  ? 83.542  127.010 53.865  1.00 173.96 ? 24  ASN C C   1 
ATOM 4504 O O   . ASN C 3 24  ? 83.256  126.335 52.871  1.00 173.28 ? 24  ASN C O   1 
ATOM 4505 C CB  . ASN C 3 24  ? 85.011  128.544 52.544  1.00 173.67 ? 24  ASN C CB  1 
ATOM 4506 C CG  . ASN C 3 24  ? 85.140  129.950 51.991  1.00 173.47 ? 24  ASN C CG  1 
ATOM 4507 O OD1 . ASN C 3 24  ? 84.411  130.340 51.079  1.00 173.18 ? 24  ASN C OD1 1 
ATOM 4508 N ND2 . ASN C 3 24  ? 86.071  130.720 52.541  1.00 173.42 ? 24  ASN C ND2 1 
ATOM 4509 N N   . ILE C 3 25  ? 83.467  126.526 55.100  1.00 172.38 ? 25  ILE C N   1 
ATOM 4510 C CA  . ILE C 3 25  ? 83.053  125.157 55.367  1.00 173.08 ? 25  ILE C CA  1 
ATOM 4511 C C   . ILE C 3 25  ? 81.532  125.091 55.426  1.00 172.72 ? 25  ILE C C   1 
ATOM 4512 O O   . ILE C 3 25  ? 80.848  126.081 55.695  1.00 171.26 ? 25  ILE C O   1 
ATOM 4513 C CB  . ILE C 3 25  ? 83.681  124.620 56.669  1.00 172.33 ? 25  ILE C CB  1 
ATOM 4514 C CG1 . ILE C 3 25  ? 83.176  125.421 57.871  1.00 172.19 ? 25  ILE C CG1 1 
ATOM 4515 C CG2 . ILE C 3 25  ? 85.199  124.670 56.588  1.00 171.15 ? 25  ILE C CG2 1 
ATOM 4516 C CD1 . ILE C 3 25  ? 83.725  124.946 59.196  1.00 170.37 ? 25  ILE C CD1 1 
ATOM 4517 N N   . ASP C 3 26  ? 80.996  123.902 55.164  1.00 177.41 ? 26  ASP C N   1 
ATOM 4518 C CA  . ASP C 3 26  ? 79.562  123.664 55.244  1.00 177.22 ? 26  ASP C CA  1 
ATOM 4519 C C   . ASP C 3 26  ? 79.184  123.328 56.681  1.00 176.44 ? 26  ASP C C   1 
ATOM 4520 O O   . ASP C 3 26  ? 79.783  122.440 57.295  1.00 176.03 ? 26  ASP C O   1 
ATOM 4521 C CB  . ASP C 3 26  ? 79.147  122.531 54.305  1.00 176.74 ? 26  ASP C CB  1 
ATOM 4522 C CG  . ASP C 3 26  ? 77.658  122.251 54.352  1.00 176.93 ? 26  ASP C CG  1 
ATOM 4523 O OD1 . ASP C 3 26  ? 76.877  123.096 53.867  1.00 176.68 ? 26  ASP C OD1 1 
ATOM 4524 O OD2 . ASP C 3 26  ? 77.269  121.186 54.875  1.00 177.42 ? 26  ASP C OD2 1 
ATOM 4525 N N   . ARG C 3 27  ? 78.194  124.039 57.211  1.00 171.90 ? 27  ARG C N   1 
ATOM 4526 C CA  . ARG C 3 27  ? 77.734  123.854 58.580  1.00 171.90 ? 27  ARG C CA  1 
ATOM 4527 C C   . ARG C 3 27  ? 76.306  123.327 58.571  1.00 172.72 ? 27  ARG C C   1 
ATOM 4528 O O   . ARG C 3 27  ? 75.435  123.889 57.899  1.00 173.61 ? 27  ARG C O   1 
ATOM 4529 C CB  . ARG C 3 27  ? 77.814  125.169 59.358  1.00 170.97 ? 27  ARG C CB  1 
ATOM 4530 C CG  . ARG C 3 27  ? 79.221  125.742 59.444  1.00 171.09 ? 27  ARG C CG  1 
ATOM 4531 C CD  . ARG C 3 27  ? 79.237  127.093 60.138  1.00 172.62 ? 27  ARG C CD  1 
ATOM 4532 N NE  . ARG C 3 27  ? 80.589  127.629 60.248  1.00 173.03 ? 27  ARG C NE  1 
ATOM 4533 C CZ  . ARG C 3 27  ? 81.181  128.365 59.317  1.00 173.07 ? 27  ARG C CZ  1 
ATOM 4534 N NH1 . ARG C 3 27  ? 80.567  128.674 58.186  1.00 173.42 ? 27  ARG C NH1 1 
ATOM 4535 N NH2 . ARG C 3 27  ? 82.420  128.800 59.525  1.00 171.79 ? 27  ARG C NH2 1 
ATOM 4536 N N   . ILE C 3 28  ? 76.073  122.251 59.317  1.00 164.83 ? 28  ILE C N   1 
ATOM 4537 C CA  . ILE C 3 28  ? 74.734  121.712 59.497  1.00 164.93 ? 28  ILE C CA  1 
ATOM 4538 C C   . ILE C 3 28  ? 74.079  122.366 60.707  1.00 165.21 ? 28  ILE C C   1 
ATOM 4539 O O   . ILE C 3 28  ? 74.735  123.000 61.538  1.00 163.55 ? 28  ILE C O   1 
ATOM 4540 C CB  . ILE C 3 28  ? 74.759  120.177 59.642  1.00 163.40 ? 28  ILE C CB  1 
ATOM 4541 C CG1 . ILE C 3 28  ? 75.536  119.773 60.896  1.00 163.01 ? 28  ILE C CG1 1 
ATOM 4542 C CG2 . ILE C 3 28  ? 75.365  119.535 58.403  1.00 162.87 ? 28  ILE C CG2 1 
ATOM 4543 C CD1 . ILE C 3 28  ? 75.555  118.281 61.148  1.00 161.30 ? 28  ILE C CD1 1 
ATOM 4544 N N   . LYS C 3 29  ? 72.761  122.211 60.801  1.00 163.92 ? 29  LYS C N   1 
ATOM 4545 C CA  . LYS C 3 29  ? 72.010  122.771 61.915  1.00 163.26 ? 29  LYS C CA  1 
ATOM 4546 C C   . LYS C 3 29  ? 72.384  122.081 63.222  1.00 163.25 ? 29  LYS C C   1 
ATOM 4547 O O   . LYS C 3 29  ? 72.793  120.916 63.244  1.00 162.42 ? 29  LYS C O   1 
ATOM 4548 C CB  . LYS C 3 29  ? 70.508  122.638 61.665  1.00 162.06 ? 29  LYS C CB  1 
ATOM 4549 C CG  . LYS C 3 29  ? 70.006  123.412 60.457  1.00 162.43 ? 29  LYS C CG  1 
ATOM 4550 C CD  . LYS C 3 29  ? 70.200  124.908 60.637  1.00 162.25 ? 29  LYS C CD  1 
ATOM 4551 C CE  . LYS C 3 29  ? 69.669  125.682 59.441  1.00 161.68 ? 29  LYS C CE  1 
ATOM 4552 N NZ  . LYS C 3 29  ? 69.837  127.152 59.611  1.00 161.19 ? 29  LYS C NZ  1 
ATOM 4553 N N   . VAL C 3 30  ? 72.246  122.822 64.324  1.00 158.64 ? 30  VAL C N   1 
ATOM 4554 C CA  . VAL C 3 30  ? 72.540  122.263 65.642  1.00 157.61 ? 30  VAL C CA  1 
ATOM 4555 C C   . VAL C 3 30  ? 71.566  121.139 65.975  1.00 157.36 ? 30  VAL C C   1 
ATOM 4556 O O   . VAL C 3 30  ? 71.937  120.142 66.608  1.00 155.97 ? 30  VAL C O   1 
ATOM 4557 C CB  . VAL C 3 30  ? 72.516  123.375 66.708  1.00 156.90 ? 30  VAL C CB  1 
ATOM 4558 C CG1 . VAL C 3 30  ? 72.673  122.791 68.104  1.00 155.72 ? 30  VAL C CG1 1 
ATOM 4559 C CG2 . VAL C 3 30  ? 73.610  124.393 66.432  1.00 156.21 ? 30  VAL C CG2 1 
ATOM 4560 N N   . SER C 3 31  ? 70.309  121.274 65.544  1.00 160.11 ? 31  SER C N   1 
ATOM 4561 C CA  . SER C 3 31  ? 69.329  120.216 65.769  1.00 159.79 ? 31  SER C CA  1 
ATOM 4562 C C   . SER C 3 31  ? 69.732  118.926 65.064  1.00 158.58 ? 31  SER C C   1 
ATOM 4563 O O   . SER C 3 31  ? 69.579  117.832 65.620  1.00 157.77 ? 31  SER C O   1 
ATOM 4564 C CB  . SER C 3 31  ? 67.948  120.674 65.300  1.00 159.82 ? 31  SER C CB  1 
ATOM 4565 O OG  . SER C 3 31  ? 67.958  120.993 63.920  1.00 159.66 ? 31  SER C OG  1 
ATOM 4566 N N   . LYS C 3 32  ? 70.242  119.034 63.835  1.00 153.66 ? 32  LYS C N   1 
ATOM 4567 C CA  . LYS C 3 32  ? 70.730  117.852 63.130  1.00 153.84 ? 32  LYS C CA  1 
ATOM 4568 C C   . LYS C 3 32  ? 71.927  117.238 63.846  1.00 153.76 ? 32  LYS C C   1 
ATOM 4569 O O   . LYS C 3 32  ? 72.014  116.012 63.988  1.00 154.47 ? 32  LYS C O   1 
ATOM 4570 C CB  . LYS C 3 32  ? 71.090  118.212 61.689  1.00 152.70 ? 32  LYS C CB  1 
ATOM 4571 C CG  . LYS C 3 32  ? 71.659  117.054 60.886  1.00 153.02 ? 32  LYS C CG  1 
ATOM 4572 C CD  . LYS C 3 32  ? 70.669  115.904 60.800  1.00 153.57 ? 32  LYS C CD  1 
ATOM 4573 C CE  . LYS C 3 32  ? 71.241  114.742 60.005  1.00 152.67 ? 32  LYS C CE  1 
ATOM 4574 N NZ  . LYS C 3 32  ? 70.282  113.606 59.914  1.00 152.75 ? 32  LYS C NZ  1 
ATOM 4575 N N   . ALA C 3 33  ? 72.862  118.074 64.301  1.00 146.02 ? 33  ALA C N   1 
ATOM 4576 C CA  . ALA C 3 33  ? 74.031  117.565 65.011  1.00 145.33 ? 33  ALA C CA  1 
ATOM 4577 C C   . ALA C 3 33  ? 73.649  116.977 66.364  1.00 145.36 ? 33  ALA C C   1 
ATOM 4578 O O   . ALA C 3 33  ? 74.202  115.951 66.778  1.00 144.61 ? 33  ALA C O   1 
ATOM 4579 C CB  . ALA C 3 33  ? 75.066  118.677 65.181  1.00 144.04 ? 33  ALA C CB  1 
ATOM 4580 N N   . ALA C 3 34  ? 72.713  117.616 67.069  1.00 143.31 ? 34  ALA C N   1 
ATOM 4581 C CA  . ALA C 3 34  ? 72.277  117.099 68.363  1.00 143.16 ? 34  ALA C CA  1 
ATOM 4582 C C   . ALA C 3 34  ? 71.600  115.741 68.220  1.00 143.45 ? 34  ALA C C   1 
ATOM 4583 O O   . ALA C 3 34  ? 71.803  114.848 69.051  1.00 142.95 ? 34  ALA C O   1 
ATOM 4584 C CB  . ALA C 3 34  ? 71.337  118.098 69.037  1.00 143.69 ? 34  ALA C CB  1 
ATOM 4585 N N   . ALA C 3 35  ? 70.782  115.572 67.178  1.00 142.63 ? 35  ALA C N   1 
ATOM 4586 C CA  . ALA C 3 35  ? 70.088  114.304 66.976  1.00 142.88 ? 35  ALA C CA  1 
ATOM 4587 C C   . ALA C 3 35  ? 71.069  113.167 66.717  1.00 142.20 ? 35  ALA C C   1 
ATOM 4588 O O   . ALA C 3 35  ? 70.870  112.045 67.198  1.00 142.01 ? 35  ALA C O   1 
ATOM 4589 C CB  . ALA C 3 35  ? 69.094  114.429 65.823  1.00 142.93 ? 35  ALA C CB  1 
ATOM 4590 N N   . ASP C 3 36  ? 72.130  113.436 65.952  1.00 138.35 ? 36  ASP C N   1 
ATOM 4591 C CA  . ASP C 3 36  ? 73.111  112.398 65.649  1.00 138.70 ? 36  ASP C CA  1 
ATOM 4592 C C   . ASP C 3 36  ? 73.823  111.917 66.908  1.00 138.88 ? 36  ASP C C   1 
ATOM 4593 O O   . ASP C 3 36  ? 74.054  110.714 67.077  1.00 138.92 ? 36  ASP C O   1 
ATOM 4594 C CB  . ASP C 3 36  ? 74.122  112.916 64.625  1.00 139.24 ? 36  ASP C CB  1 
ATOM 4595 C CG  . ASP C 3 36  ? 73.473  113.309 63.312  1.00 140.11 ? 36  ASP C CG  1 
ATOM 4596 O OD1 . ASP C 3 36  ? 72.237  113.172 63.193  1.00 140.20 ? 36  ASP C OD1 1 
ATOM 4597 O OD2 . ASP C 3 36  ? 74.199  113.754 62.398  1.00 140.21 ? 36  ASP C OD2 1 
ATOM 4598 N N   . LEU C 3 37  ? 74.187  112.842 67.799  1.00 123.77 ? 37  LEU C N   1 
ATOM 4599 C CA  . LEU C 3 37  ? 74.808  112.447 69.060  1.00 122.41 ? 37  LEU C CA  1 
ATOM 4600 C C   . LEU C 3 37  ? 73.844  111.646 69.927  1.00 122.44 ? 37  LEU C C   1 
ATOM 4601 O O   . LEU C 3 37  ? 74.236  110.653 70.551  1.00 122.10 ? 37  LEU C O   1 
ATOM 4602 C CB  . LEU C 3 37  ? 75.302  113.685 69.810  1.00 119.88 ? 37  LEU C CB  1 
ATOM 4603 C CG  . LEU C 3 37  ? 76.426  114.480 69.144  1.00 121.13 ? 37  LEU C CG  1 
ATOM 4604 C CD1 . LEU C 3 37  ? 76.794  115.690 69.986  1.00 121.91 ? 37  LEU C CD1 1 
ATOM 4605 C CD2 . LEU C 3 37  ? 77.641  113.595 68.916  1.00 120.45 ? 37  LEU C CD2 1 
ATOM 4606 N N   . MET C 3 38  ? 72.579  112.067 69.984  1.00 122.33 ? 38  MET C N   1 
ATOM 4607 C CA  . MET C 3 38  ? 71.585  111.334 70.762  1.00 121.05 ? 38  MET C CA  1 
ATOM 4608 C C   . MET C 3 38  ? 71.311  109.959 70.165  1.00 120.62 ? 38  MET C C   1 
ATOM 4609 O O   . MET C 3 38  ? 71.123  108.983 70.901  1.00 120.45 ? 38  MET C O   1 
ATOM 4610 C CB  . MET C 3 38  ? 70.294  112.147 70.852  1.00 122.86 ? 38  MET C CB  1 
ATOM 4611 C CG  . MET C 3 38  ? 69.191  111.485 71.658  1.00 123.89 ? 38  MET C CG  1 
ATOM 4612 S SD  . MET C 3 38  ? 67.706  112.502 71.742  1.00 125.91 ? 38  MET C SD  1 
ATOM 4613 C CE  . MET C 3 38  ? 67.328  112.686 70.002  1.00 123.52 ? 38  MET C CE  1 
ATOM 4614 N N   . ALA C 3 39  ? 71.280  109.863 68.834  1.00 121.88 ? 39  ALA C N   1 
ATOM 4615 C CA  . ALA C 3 39  ? 71.035  108.579 68.184  1.00 123.25 ? 39  ALA C CA  1 
ATOM 4616 C C   . ALA C 3 39  ? 72.163  107.587 68.445  1.00 122.72 ? 39  ALA C C   1 
ATOM 4617 O O   . ALA C 3 39  ? 71.908  106.399 68.673  1.00 123.05 ? 39  ALA C O   1 
ATOM 4618 C CB  . ALA C 3 39  ? 70.840  108.783 66.682  1.00 122.13 ? 39  ALA C CB  1 
ATOM 4619 N N   . TYR C 3 40  ? 73.415  108.051 68.404  1.00 105.41 ? 40  TYR C N   1 
ATOM 4620 C CA  . TYR C 3 40  ? 74.545  107.146 68.601  1.00 104.52 ? 40  TYR C CA  1 
ATOM 4621 C C   . TYR C 3 40  ? 74.537  106.537 69.999  1.00 105.67 ? 40  TYR C C   1 
ATOM 4622 O O   . TYR C 3 40  ? 74.817  105.344 70.164  1.00 106.83 ? 40  TYR C O   1 
ATOM 4623 C CB  . TYR C 3 40  ? 75.860  107.882 68.347  1.00 102.40 ? 40  TYR C CB  1 
ATOM 4624 C CG  . TYR C 3 40  ? 77.088  107.017 68.531  1.00 103.25 ? 40  TYR C CG  1 
ATOM 4625 C CD1 . TYR C 3 40  ? 77.534  106.188 67.513  1.00 103.40 ? 40  TYR C CD1 1 
ATOM 4626 C CD2 . TYR C 3 40  ? 77.799  107.029 69.724  1.00 100.92 ? 40  TYR C CD2 1 
ATOM 4627 C CE1 . TYR C 3 40  ? 78.655  105.395 67.674  1.00 103.53 ? 40  TYR C CE1 1 
ATOM 4628 C CE2 . TYR C 3 40  ? 78.920  106.239 69.895  1.00 100.44 ? 40  TYR C CE2 1 
ATOM 4629 C CZ  . TYR C 3 40  ? 79.344  105.425 68.867  1.00 102.08 ? 40  TYR C CZ  1 
ATOM 4630 O OH  . TYR C 3 40  ? 80.459  104.636 69.032  1.00 100.54 ? 40  TYR C OH  1 
ATOM 4631 N N   . CYS C 3 41  ? 74.229  107.343 71.018  1.00 110.78 ? 41  CYS C N   1 
ATOM 4632 C CA  . CYS C 3 41  ? 74.173  106.821 72.381  1.00 111.98 ? 41  CYS C CA  1 
ATOM 4633 C C   . CYS C 3 41  ? 73.077  105.774 72.528  1.00 113.52 ? 41  CYS C C   1 
ATOM 4634 O O   . CYS C 3 41  ? 73.269  104.754 73.201  1.00 112.26 ? 41  CYS C O   1 
ATOM 4635 C CB  . CYS C 3 41  ? 73.961  107.966 73.371  1.00 110.43 ? 41  CYS C CB  1 
ATOM 4636 S SG  . CYS C 3 41  ? 75.274  109.208 73.371  1.00 117.79 ? 41  CYS C SG  1 
ATOM 4637 N N   . GLU C 3 42  ? 71.917  106.013 71.913  1.00 115.71 ? 42  GLU C N   1 
ATOM 4638 C CA  . GLU C 3 42  ? 70.814  105.062 72.007  1.00 112.86 ? 42  GLU C CA  1 
ATOM 4639 C C   . GLU C 3 42  ? 71.165  103.734 71.345  1.00 112.47 ? 42  GLU C C   1 
ATOM 4640 O O   . GLU C 3 42  ? 70.842  102.664 71.875  1.00 111.59 ? 42  GLU C O   1 
ATOM 4641 C CB  . GLU C 3 42  ? 69.554  105.658 71.380  1.00 112.15 ? 42  GLU C CB  1 
ATOM 4642 C CG  . GLU C 3 42  ? 68.324  104.774 71.500  1.00 113.11 ? 42  GLU C CG  1 
ATOM 4643 C CD  . GLU C 3 42  ? 67.071  105.446 70.978  1.00 113.58 ? 42  GLU C CD  1 
ATOM 4644 O OE1 . GLU C 3 42  ? 67.150  106.627 70.580  1.00 112.87 ? 42  GLU C OE1 1 
ATOM 4645 O OE2 . GLU C 3 42  ? 66.006  104.794 70.964  1.00 114.47 ? 42  GLU C OE2 1 
ATOM 4646 N N   . ALA C 3 43  ? 71.822  103.783 70.183  1.00 107.07 ? 43  ALA C N   1 
ATOM 4647 C CA  . ALA C 3 43  ? 72.114  102.558 69.446  1.00 107.43 ? 43  ALA C CA  1 
ATOM 4648 C C   . ALA C 3 43  ? 73.116  101.674 70.178  1.00 107.99 ? 43  ALA C C   1 
ATOM 4649 O O   . ALA C 3 43  ? 73.031  100.444 70.091  1.00 109.46 ? 43  ALA C O   1 
ATOM 4650 C CB  . ALA C 3 43  ? 72.631  102.897 68.048  1.00 106.24 ? 43  ALA C CB  1 
ATOM 4651 N N   . HIS C 3 44  ? 74.066  102.271 70.895  1.00 102.86 ? 44  HIS C N   1 
ATOM 4652 C CA  . HIS C 3 44  ? 75.111  101.520 71.580  1.00 103.53 ? 44  HIS C CA  1 
ATOM 4653 C C   . HIS C 3 44  ? 74.890  101.458 73.086  1.00 106.43 ? 44  HIS C C   1 
ATOM 4654 O O   . HIS C 3 44  ? 75.812  101.095 73.824  1.00 107.86 ? 44  HIS C O   1 
ATOM 4655 C CB  . HIS C 3 44  ? 76.483  102.120 71.268  1.00 101.72 ? 44  HIS C CB  1 
ATOM 4656 C CG  . HIS C 3 44  ? 76.902  101.956 69.840  1.00 105.04 ? 44  HIS C CG  1 
ATOM 4657 N ND1 . HIS C 3 44  ? 77.938  101.132 69.457  1.00 106.16 ? 44  HIS C ND1 1 
ATOM 4658 C CD2 . HIS C 3 44  ? 76.420  102.507 68.700  1.00 105.60 ? 44  HIS C CD2 1 
ATOM 4659 C CE1 . HIS C 3 44  ? 78.079  101.183 68.145  1.00 106.15 ? 44  HIS C CE1 1 
ATOM 4660 N NE2 . HIS C 3 44  ? 77.170  102.011 67.661  1.00 105.28 ? 44  HIS C NE2 1 
ATOM 4661 N N   . ALA C 3 45  ? 73.689  101.806 73.557  1.00 105.96 ? 45  ALA C N   1 
ATOM 4662 C CA  . ALA C 3 45  ? 73.430  101.855 74.993  1.00 105.49 ? 45  ALA C CA  1 
ATOM 4663 C C   . ALA C 3 45  ? 73.544  100.476 75.630  1.00 104.72 ? 45  ALA C C   1 
ATOM 4664 O O   . ALA C 3 45  ? 74.086  100.337 76.733  1.00 103.06 ? 45  ALA C O   1 
ATOM 4665 C CB  . ALA C 3 45  ? 72.049  102.455 75.257  1.00 102.86 ? 45  ALA C CB  1 
ATOM 4666 N N   . LYS C 3 46  ? 73.034  99.444  74.953  1.00 102.16 ? 46  LYS C N   1 
ATOM 4667 C CA  . LYS C 3 46  ? 72.991  98.116  75.557  1.00 102.73 ? 46  LYS C CA  1 
ATOM 4668 C C   . LYS C 3 46  ? 74.384  97.522  75.721  1.00 103.01 ? 46  LYS C C   1 
ATOM 4669 O O   . LYS C 3 46  ? 74.629  96.781  76.680  1.00 100.94 ? 46  LYS C O   1 
ATOM 4670 C CB  . LYS C 3 46  ? 72.115  97.187  74.717  1.00 102.10 ? 46  LYS C CB  1 
ATOM 4671 C CG  . LYS C 3 46  ? 70.683  97.668  74.553  1.00 102.96 ? 46  LYS C CG  1 
ATOM 4672 C CD  . LYS C 3 46  ? 69.994  97.819  75.899  1.00 103.64 ? 46  LYS C CD  1 
ATOM 4673 C CE  . LYS C 3 46  ? 68.564  98.307  75.736  1.00 102.84 ? 46  LYS C CE  1 
ATOM 4674 N NZ  . LYS C 3 46  ? 67.875  98.457  77.047  1.00 101.34 ? 46  LYS C NZ  1 
ATOM 4675 N N   . GLU C 3 47  ? 75.303  97.828  74.807  1.00 101.39 ? 47  GLU C N   1 
ATOM 4676 C CA  . GLU C 3 47  ? 76.662  97.314  74.874  1.00 99.38  ? 47  GLU C CA  1 
ATOM 4677 C C   . GLU C 3 47  ? 77.599  98.239  75.644  1.00 98.74  ? 47  GLU C C   1 
ATOM 4678 O O   . GLU C 3 47  ? 78.815  98.199  75.426  1.00 97.74  ? 47  GLU C O   1 
ATOM 4679 C CB  . GLU C 3 47  ? 77.203  97.062  73.464  1.00 98.92  ? 47  GLU C CB  1 
ATOM 4680 C CG  . GLU C 3 47  ? 77.175  98.277  72.553  1.00 98.66  ? 47  GLU C CG  1 
ATOM 4681 C CD  . GLU C 3 47  ? 77.646  97.958  71.147  1.00 100.65 ? 47  GLU C CD  1 
ATOM 4682 O OE1 . GLU C 3 47  ? 77.980  96.784  70.882  1.00 101.60 ? 47  GLU C OE1 1 
ATOM 4683 O OE2 . GLU C 3 47  ? 77.683  98.882  70.306  1.00 100.74 ? 47  GLU C OE2 1 
ATOM 4684 N N   . ASP C 3 48  ? 77.059  99.068  76.537  1.00 97.77  ? 48  ASP C N   1 
ATOM 4685 C CA  . ASP C 3 48  ? 77.864  99.940  77.386  1.00 97.61  ? 48  ASP C CA  1 
ATOM 4686 C C   . ASP C 3 48  ? 77.819  99.423  78.817  1.00 99.49  ? 48  ASP C C   1 
ATOM 4687 O O   . ASP C 3 48  ? 76.819  99.635  79.522  1.00 100.30 ? 48  ASP C O   1 
ATOM 4688 C CB  . ASP C 3 48  ? 77.358  101.384 77.318  1.00 98.72  ? 48  ASP C CB  1 
ATOM 4689 C CG  . ASP C 3 48  ? 78.347  102.377 77.898  1.00 99.29  ? 48  ASP C CG  1 
ATOM 4690 O OD1 . ASP C 3 48  ? 79.458  101.958 78.283  1.00 94.62  ? 48  ASP C OD1 1 
ATOM 4691 O OD2 . ASP C 3 48  ? 78.013  103.579 77.968  1.00 101.82 ? 48  ASP C OD2 1 
ATOM 4692 N N   . PRO C 3 49  ? 78.859  98.733  79.288  1.00 86.35  ? 49  PRO C N   1 
ATOM 4693 C CA  . PRO C 3 49  ? 78.824  98.196  80.659  1.00 84.96  ? 49  PRO C CA  1 
ATOM 4694 C C   . PRO C 3 49  ? 78.716  99.257  81.741  1.00 83.58  ? 49  PRO C C   1 
ATOM 4695 O O   . PRO C 3 49  ? 78.083  99.007  82.773  1.00 81.73  ? 49  PRO C O   1 
ATOM 4696 C CB  . PRO C 3 49  ? 80.146  97.422  80.760  1.00 81.91  ? 49  PRO C CB  1 
ATOM 4697 C CG  . PRO C 3 49  ? 80.493  97.084  79.346  1.00 81.13  ? 49  PRO C CG  1 
ATOM 4698 C CD  . PRO C 3 49  ? 80.029  98.255  78.534  1.00 81.67  ? 49  PRO C CD  1 
ATOM 4699 N N   . LEU C 3 50  ? 79.317  100.433 81.548  1.00 77.35  ? 50  LEU C N   1 
ATOM 4700 C CA  . LEU C 3 50  ? 79.228  101.470 82.571  1.00 76.97  ? 50  LEU C CA  1 
ATOM 4701 C C   . LEU C 3 50  ? 77.819  102.043 82.669  1.00 77.07  ? 50  LEU C C   1 
ATOM 4702 O O   . LEU C 3 50  ? 77.329  102.310 83.773  1.00 76.59  ? 50  LEU C O   1 
ATOM 4703 C CB  . LEU C 3 50  ? 80.239  102.579 82.281  1.00 77.92  ? 50  LEU C CB  1 
ATOM 4704 C CG  . LEU C 3 50  ? 81.713  102.172 82.325  1.00 75.84  ? 50  LEU C CG  1 
ATOM 4705 C CD1 . LEU C 3 50  ? 82.611  103.381 82.122  1.00 77.59  ? 50  LEU C CD1 1 
ATOM 4706 C CD2 . LEU C 3 50  ? 82.040  101.471 83.633  1.00 72.64  ? 50  LEU C CD2 1 
ATOM 4707 N N   . LEU C 3 51  ? 77.153  102.244 81.531  1.00 86.74  ? 51  LEU C N   1 
ATOM 4708 C CA  . LEU C 3 51  ? 75.780  102.736 81.556  1.00 86.88  ? 51  LEU C CA  1 
ATOM 4709 C C   . LEU C 3 51  ? 74.824  101.678 82.094  1.00 89.92  ? 51  LEU C C   1 
ATOM 4710 O O   . LEU C 3 51  ? 73.998  101.957 82.971  1.00 92.28  ? 51  LEU C O   1 
ATOM 4711 C CB  . LEU C 3 51  ? 75.360  103.185 80.157  1.00 87.84  ? 51  LEU C CB  1 
ATOM 4712 C CG  . LEU C 3 51  ? 73.909  103.643 80.004  1.00 90.72  ? 51  LEU C CG  1 
ATOM 4713 C CD1 . LEU C 3 51  ? 73.623  104.821 80.921  1.00 90.28  ? 51  LEU C CD1 1 
ATOM 4714 C CD2 . LEU C 3 51  ? 73.608  104.000 78.558  1.00 88.24  ? 51  LEU C CD2 1 
ATOM 4715 N N   . THR C 3 52  ? 74.923  100.456 81.578  1.00 103.53 ? 52  THR C N   1 
ATOM 4716 C CA  . THR C 3 52  ? 74.094  99.331  82.012  1.00 106.36 ? 52  THR C CA  1 
ATOM 4717 C C   . THR C 3 52  ? 75.007  98.232  82.534  1.00 104.62 ? 52  THR C C   1 
ATOM 4718 O O   . THR C 3 52  ? 75.585  97.473  81.734  1.00 103.98 ? 52  THR C O   1 
ATOM 4719 C CB  . THR C 3 52  ? 73.224  98.811  80.869  1.00 107.59 ? 52  THR C CB  1 
ATOM 4720 O OG1 . THR C 3 52  ? 74.058  98.384  79.784  1.00 105.86 ? 52  THR C OG1 1 
ATOM 4721 C CG2 . THR C 3 52  ? 72.279  99.899  80.379  1.00 106.82 ? 52  THR C CG2 1 
ATOM 4722 N N   . PRO C 3 53  ? 75.189  98.117  83.850  1.00 106.78 ? 53  PRO C N   1 
ATOM 4723 C CA  . PRO C 3 53  ? 76.126  97.118  84.379  1.00 106.22 ? 53  PRO C CA  1 
ATOM 4724 C C   . PRO C 3 53  ? 75.751  95.706  83.955  1.00 107.28 ? 53  PRO C C   1 
ATOM 4725 O O   . PRO C 3 53  ? 74.578  95.327  83.941  1.00 106.45 ? 53  PRO C O   1 
ATOM 4726 C CB  . PRO C 3 53  ? 76.017  97.300  85.898  1.00 104.83 ? 53  PRO C CB  1 
ATOM 4727 C CG  . PRO C 3 53  ? 74.688  97.952  86.111  1.00 106.56 ? 53  PRO C CG  1 
ATOM 4728 C CD  . PRO C 3 53  ? 74.482  98.838  84.921  1.00 108.02 ? 53  PRO C CD  1 
ATOM 4729 N N   . VAL C 3 54  ? 76.773  94.929  83.610  1.00 118.53 ? 54  VAL C N   1 
ATOM 4730 C CA  . VAL C 3 54  ? 76.602  93.567  83.112  1.00 118.74 ? 54  VAL C CA  1 
ATOM 4731 C C   . VAL C 3 54  ? 76.400  92.621  84.290  1.00 120.28 ? 54  VAL C C   1 
ATOM 4732 O O   . VAL C 3 54  ? 76.741  92.972  85.429  1.00 121.06 ? 54  VAL C O   1 
ATOM 4733 C CB  . VAL C 3 54  ? 77.806  93.140  82.257  1.00 117.00 ? 54  VAL C CB  1 
ATOM 4734 C CG1 . VAL C 3 54  ? 77.945  94.049  81.045  1.00 117.10 ? 54  VAL C CG1 1 
ATOM 4735 C CG2 . VAL C 3 54  ? 79.079  93.155  83.089  1.00 116.22 ? 54  VAL C CG2 1 
ATOM 4736 N N   . PRO C 3 55  ? 75.841  91.430  84.073  1.00 126.59 ? 55  PRO C N   1 
ATOM 4737 C CA  . PRO C 3 55  ? 75.762  90.448  85.158  1.00 125.70 ? 55  PRO C CA  1 
ATOM 4738 C C   . PRO C 3 55  ? 77.148  90.058  85.649  1.00 125.96 ? 55  PRO C C   1 
ATOM 4739 O O   . PRO C 3 55  ? 78.130  90.101  84.905  1.00 126.24 ? 55  PRO C O   1 
ATOM 4740 C CB  . PRO C 3 55  ? 75.040  89.260  84.512  1.00 124.82 ? 55  PRO C CB  1 
ATOM 4741 C CG  . PRO C 3 55  ? 74.251  89.865  83.402  1.00 125.59 ? 55  PRO C CG  1 
ATOM 4742 C CD  . PRO C 3 55  ? 75.090  90.996  82.881  1.00 125.50 ? 55  PRO C CD  1 
ATOM 4743 N N   . ALA C 3 56  ? 77.217  89.689  86.932  1.00 120.22 ? 56  ALA C N   1 
ATOM 4744 C CA  . ALA C 3 56  ? 78.499  89.389  87.562  1.00 120.25 ? 56  ALA C CA  1 
ATOM 4745 C C   . ALA C 3 56  ? 79.246  88.277  86.837  1.00 120.97 ? 56  ALA C C   1 
ATOM 4746 O O   . ALA C 3 56  ? 80.481  88.228  86.884  1.00 121.36 ? 56  ALA C O   1 
ATOM 4747 C CB  . ALA C 3 56  ? 78.288  89.015  89.030  1.00 116.87 ? 56  ALA C CB  1 
ATOM 4748 N N   . SER C 3 57  ? 78.523  87.377  86.165  1.00 117.24 ? 57  SER C N   1 
ATOM 4749 C CA  . SER C 3 57  ? 79.182  86.306  85.424  1.00 114.11 ? 57  SER C CA  1 
ATOM 4750 C C   . SER C 3 57  ? 79.985  86.847  84.248  1.00 115.69 ? 57  SER C C   1 
ATOM 4751 O O   . SER C 3 57  ? 80.992  86.245  83.859  1.00 119.16 ? 57  SER C O   1 
ATOM 4752 C CB  . SER C 3 57  ? 78.148  85.292  84.937  1.00 114.88 ? 57  SER C CB  1 
ATOM 4753 O OG  . SER C 3 57  ? 77.199  85.905  84.082  1.00 117.25 ? 57  SER C OG  1 
ATOM 4754 N N   . GLU C 3 58  ? 79.559  87.968  83.669  1.00 117.78 ? 58  GLU C N   1 
ATOM 4755 C CA  . GLU C 3 58  ? 80.225  88.557  82.517  1.00 119.69 ? 58  GLU C CA  1 
ATOM 4756 C C   . GLU C 3 58  ? 81.161  89.694  82.903  1.00 120.93 ? 58  GLU C C   1 
ATOM 4757 O O   . GLU C 3 58  ? 81.717  90.355  82.020  1.00 118.68 ? 58  GLU C O   1 
ATOM 4758 C CB  . GLU C 3 58  ? 79.189  89.050  81.505  1.00 121.29 ? 58  GLU C CB  1 
ATOM 4759 C CG  . GLU C 3 58  ? 78.301  87.951  80.948  1.00 121.10 ? 58  GLU C CG  1 
ATOM 4760 C CD  . GLU C 3 58  ? 77.315  88.463  79.919  1.00 123.59 ? 58  GLU C CD  1 
ATOM 4761 O OE1 . GLU C 3 58  ? 77.322  89.681  79.642  1.00 124.41 ? 58  GLU C OE1 1 
ATOM 4762 O OE2 . GLU C 3 58  ? 76.532  87.648  79.388  1.00 123.80 ? 58  GLU C OE2 1 
ATOM 4763 N N   . ASN C 3 59  ? 81.350  89.936  84.201  1.00 107.81 ? 59  ASN C N   1 
ATOM 4764 C CA  . ASN C 3 59  ? 82.171  91.040  84.669  1.00 104.47 ? 59  ASN C CA  1 
ATOM 4765 C C   . ASN C 3 59  ? 83.566  90.526  84.985  1.00 103.67 ? 59  ASN C C   1 
ATOM 4766 O O   . ASN C 3 59  ? 83.720  89.715  85.910  1.00 101.29 ? 59  ASN C O   1 
ATOM 4767 C CB  . ASN C 3 59  ? 81.549  91.691  85.903  1.00 103.17 ? 59  ASN C CB  1 
ATOM 4768 C CG  . ASN C 3 59  ? 82.262  92.965  86.312  1.00 102.39 ? 59  ASN C CG  1 
ATOM 4769 O OD1 . ASN C 3 59  ? 82.988  93.566  85.521  1.00 99.74  ? 59  ASN C OD1 1 
ATOM 4770 N ND2 . ASN C 3 59  ? 82.058  93.383  87.556  1.00 102.69 ? 59  ASN C ND2 1 
ATOM 4771 N N   . PRO C 3 60  ? 84.600  90.945  84.254  1.00 96.91  ? 60  PRO C N   1 
ATOM 4772 C CA  . PRO C 3 60  ? 85.961  90.478  84.567  1.00 97.02  ? 60  PRO C CA  1 
ATOM 4773 C C   . PRO C 3 60  ? 86.461  90.916  85.933  1.00 96.61  ? 60  PRO C C   1 
ATOM 4774 O O   . PRO C 3 60  ? 87.431  90.333  86.435  1.00 98.55  ? 60  PRO C O   1 
ATOM 4775 C CB  . PRO C 3 60  ? 86.810  91.088  83.442  1.00 93.70  ? 60  PRO C CB  1 
ATOM 4776 C CG  . PRO C 3 60  ? 85.838  91.394  82.345  1.00 94.72  ? 60  PRO C CG  1 
ATOM 4777 C CD  . PRO C 3 60  ? 84.565  91.771  83.036  1.00 93.88  ? 60  PRO C CD  1 
ATOM 4778 N N   . PHE C 3 61  ? 85.838  91.916  86.551  1.00 85.48  ? 61  PHE C N   1 
ATOM 4779 C CA  . PHE C 3 61  ? 86.306  92.500  87.803  1.00 84.94  ? 61  PHE C CA  1 
ATOM 4780 C C   . PHE C 3 61  ? 85.429  92.107  88.990  1.00 86.22  ? 61  PHE C C   1 
ATOM 4781 O O   . PHE C 3 61  ? 85.168  92.920  89.879  1.00 85.34  ? 61  PHE C O   1 
ATOM 4782 C CB  . PHE C 3 61  ? 86.383  94.019  87.684  1.00 80.97  ? 61  PHE C CB  1 
ATOM 4783 C CG  . PHE C 3 61  ? 87.444  94.501  86.737  1.00 80.09  ? 61  PHE C CG  1 
ATOM 4784 C CD1 . PHE C 3 61  ? 88.741  94.708  87.174  1.00 77.08  ? 61  PHE C CD1 1 
ATOM 4785 C CD2 . PHE C 3 61  ? 87.142  94.750  85.408  1.00 85.25  ? 61  PHE C CD2 1 
ATOM 4786 C CE1 . PHE C 3 61  ? 89.716  95.153  86.304  1.00 81.70  ? 61  PHE C CE1 1 
ATOM 4787 C CE2 . PHE C 3 61  ? 88.114  95.194  84.534  1.00 83.15  ? 61  PHE C CE2 1 
ATOM 4788 C CZ  . PHE C 3 61  ? 89.402  95.396  84.983  1.00 82.40  ? 61  PHE C CZ  1 
ATOM 4789 N N   . ARG C 3 62  ? 84.940  90.867  89.000  1.00 99.96  ? 62  ARG C N   1 
ATOM 4790 C CA  . ARG C 3 62  ? 84.134  90.346  90.108  1.00 102.45 ? 62  ARG C CA  1 
ATOM 4791 C C   . ARG C 3 62  ? 84.762  90.624  91.471  1.00 100.73 ? 62  ARG C C   1 
ATOM 4792 O O   . ARG C 3 62  ? 85.711  89.952  91.876  1.00 99.97  ? 62  ARG C O   1 
ATOM 4793 C CB  . ARG C 3 62  ? 83.917  88.838  89.953  1.00 103.70 ? 62  ARG C CB  1 
ATOM 4794 C CG  . ARG C 3 62  ? 83.159  88.433  88.705  1.00 103.06 ? 62  ARG C CG  1 
ATOM 4795 C CD  . ARG C 3 62  ? 83.103  86.921  88.563  1.00 101.30 ? 62  ARG C CD  1 
ATOM 4796 N NE  . ARG C 3 62  ? 82.669  86.512  87.232  1.00 103.24 ? 62  ARG C NE  1 
ATOM 4797 C CZ  . ARG C 3 62  ? 83.487  86.313  86.208  1.00 105.34 ? 62  ARG C CZ  1 
ATOM 4798 N NH1 . ARG C 3 62  ? 84.794  86.478  86.324  1.00 105.99 ? 62  ARG C NH1 1 
ATOM 4799 N NH2 . ARG C 3 62  ? 82.981  85.939  85.036  1.00 104.84 ? 62  ARG C NH2 1 
ATOM 4800 N N   . ASP D 4 1   ? 122.347 88.193  69.027  1.00 79.08  ? 1   ASP E N   1 
ATOM 4801 C CA  . ASP D 4 1   ? 121.191 87.333  68.807  1.00 81.91  ? 1   ASP E CA  1 
ATOM 4802 C C   . ASP D 4 1   ? 120.971 86.415  70.007  1.00 88.02  ? 1   ASP E C   1 
ATOM 4803 O O   . ASP D 4 1   ? 121.877 86.216  70.817  1.00 90.17  ? 1   ASP E O   1 
ATOM 4804 C CB  . ASP D 4 1   ? 121.376 86.510  67.529  1.00 84.63  ? 1   ASP E CB  1 
ATOM 4805 C CG  . ASP D 4 1   ? 120.082 85.893  67.037  1.00 86.08  ? 1   ASP E CG  1 
ATOM 4806 O OD1 . ASP D 4 1   ? 119.020 86.173  67.633  1.00 83.97  ? 1   ASP E OD1 1 
ATOM 4807 O OD2 . ASP D 4 1   ? 120.127 85.127  66.051  1.00 89.69  ? 1   ASP E OD2 1 
ATOM 4808 N N   . VAL D 4 2   ? 119.764 85.861  70.118  1.00 84.01  ? 2   VAL E N   1 
ATOM 4809 C CA  . VAL D 4 2   ? 119.442 84.982  71.236  1.00 79.14  ? 2   VAL E CA  1 
ATOM 4810 C C   . VAL D 4 2   ? 120.187 83.665  71.074  1.00 81.86  ? 2   VAL E C   1 
ATOM 4811 O O   . VAL D 4 2   ? 120.102 83.008  70.028  1.00 81.59  ? 2   VAL E O   1 
ATOM 4812 C CB  . VAL D 4 2   ? 117.926 84.758  71.326  1.00 74.11  ? 2   VAL E CB  1 
ATOM 4813 C CG1 . VAL D 4 2   ? 117.585 83.929  72.554  1.00 72.53  ? 2   VAL E CG1 1 
ATOM 4814 C CG2 . VAL D 4 2   ? 117.195 86.090  71.356  1.00 75.47  ? 2   VAL E CG2 1 
ATOM 4815 N N   . GLN D 4 3   ? 120.925 83.274  72.110  1.00 97.17  ? 3   GLN E N   1 
ATOM 4816 C CA  . GLN D 4 3   ? 121.723 82.058  72.074  1.00 100.24 ? 3   GLN E CA  1 
ATOM 4817 C C   . GLN D 4 3   ? 121.578 81.315  73.393  1.00 99.47  ? 3   GLN E C   1 
ATOM 4818 O O   . GLN D 4 3   ? 121.468 81.935  74.455  1.00 99.23  ? 3   GLN E O   1 
ATOM 4819 C CB  . GLN D 4 3   ? 123.199 82.374  71.797  1.00 98.90  ? 3   GLN E CB  1 
ATOM 4820 C CG  . GLN D 4 3   ? 124.044 81.164  71.441  1.00 99.00  ? 3   GLN E CG  1 
ATOM 4821 C CD  . GLN D 4 3   ? 125.473 81.537  71.100  1.00 102.09 ? 3   GLN E CD  1 
ATOM 4822 O OE1 . GLN D 4 3   ? 125.904 82.667  71.330  1.00 100.01 ? 3   GLN E OE1 1 
ATOM 4823 N NE2 . GLN D 4 3   ? 126.215 80.587  70.543  1.00 101.92 ? 3   GLN E NE2 1 
ATOM 4824 N N   . LEU D 4 4   ? 121.582 79.986  73.318  1.00 83.57  ? 4   LEU E N   1 
ATOM 4825 C CA  . LEU D 4 4   ? 121.568 79.128  74.501  1.00 81.08  ? 4   LEU E CA  1 
ATOM 4826 C C   . LEU D 4 4   ? 122.495 77.951  74.235  1.00 83.96  ? 4   LEU E C   1 
ATOM 4827 O O   . LEU D 4 4   ? 122.158 77.060  73.449  1.00 85.86  ? 4   LEU E O   1 
ATOM 4828 C CB  . LEU D 4 4   ? 120.155 78.643  74.825  1.00 80.32  ? 4   LEU E CB  1 
ATOM 4829 C CG  . LEU D 4 4   ? 119.181 79.660  75.419  1.00 76.09  ? 4   LEU E CG  1 
ATOM 4830 C CD1 . LEU D 4 4   ? 117.820 79.022  75.640  1.00 77.26  ? 4   LEU E CD1 1 
ATOM 4831 C CD2 . LEU D 4 4   ? 119.728 80.215  76.721  1.00 82.63  ? 4   LEU E CD2 1 
ATOM 4832 N N   . VAL D 4 5   ? 123.656 77.947  74.883  1.00 104.59 ? 5   VAL E N   1 
ATOM 4833 C CA  . VAL D 4 5   ? 124.680 76.931  74.670  1.00 107.67 ? 5   VAL E CA  1 
ATOM 4834 C C   . VAL D 4 5   ? 124.780 76.084  75.930  1.00 107.28 ? 5   VAL E C   1 
ATOM 4835 O O   . VAL D 4 5   ? 125.027 76.609  77.023  1.00 106.39 ? 5   VAL E O   1 
ATOM 4836 C CB  . VAL D 4 5   ? 126.037 77.559  74.319  1.00 107.42 ? 5   VAL E CB  1 
ATOM 4837 C CG1 . VAL D 4 5   ? 127.091 76.478  74.143  1.00 107.12 ? 5   VAL E CG1 1 
ATOM 4838 C CG2 . VAL D 4 5   ? 125.919 78.403  73.062  1.00 104.14 ? 5   VAL E CG2 1 
ATOM 4839 N N   . GLU D 4 6   ? 124.590 74.778  75.778  1.00 109.72 ? 6   GLU E N   1 
ATOM 4840 C CA  . GLU D 4 6   ? 124.692 73.835  76.880  1.00 110.10 ? 6   GLU E CA  1 
ATOM 4841 C C   . GLU D 4 6   ? 126.053 73.152  76.865  1.00 110.29 ? 6   GLU E C   1 
ATOM 4842 O O   . GLU D 4 6   ? 126.657 72.950  75.809  1.00 110.48 ? 6   GLU E O   1 
ATOM 4843 C CB  . GLU D 4 6   ? 123.581 72.784  76.812  1.00 112.47 ? 6   GLU E CB  1 
ATOM 4844 C CG  . GLU D 4 6   ? 122.178 73.339  77.001  1.00 109.15 ? 6   GLU E CG  1 
ATOM 4845 C CD  . GLU D 4 6   ? 121.561 73.840  75.709  1.00 112.72 ? 6   GLU E CD  1 
ATOM 4846 O OE1 . GLU D 4 6   ? 122.308 74.316  74.828  1.00 115.29 ? 6   GLU E OE1 1 
ATOM 4847 O OE2 . GLU D 4 6   ? 120.322 73.753  75.573  1.00 110.18 ? 6   GLU E OE2 1 
ATOM 4848 N N   . SER D 4 7   ? 126.531 72.798  78.055  1.00 105.56 ? 7   SER E N   1 
ATOM 4849 C CA  . SER D 4 7   ? 127.816 72.132  78.202  1.00 106.81 ? 7   SER E CA  1 
ATOM 4850 C C   . SER D 4 7   ? 127.787 71.286  79.466  1.00 106.05 ? 7   SER E C   1 
ATOM 4851 O O   . SER D 4 7   ? 126.896 71.421  80.309  1.00 104.79 ? 7   SER E O   1 
ATOM 4852 C CB  . SER D 4 7   ? 128.970 73.139  78.241  1.00 105.71 ? 7   SER E CB  1 
ATOM 4853 O OG  . SER D 4 7   ? 128.828 74.034  79.330  1.00 102.77 ? 7   SER E OG  1 
ATOM 4854 N N   . GLY D 4 8   ? 128.777 70.405  79.590  1.00 115.07 ? 8   GLY E N   1 
ATOM 4855 C CA  . GLY D 4 8   ? 128.889 69.524  80.731  1.00 113.88 ? 8   GLY E CA  1 
ATOM 4856 C C   . GLY D 4 8   ? 128.470 68.092  80.478  1.00 115.76 ? 8   GLY E C   1 
ATOM 4857 O O   . GLY D 4 8   ? 128.669 67.244  81.355  1.00 117.28 ? 8   GLY E O   1 
ATOM 4858 N N   . GLY D 4 9   ? 127.887 67.799  79.315  1.00 125.59 ? 9   GLY E N   1 
ATOM 4859 C CA  . GLY D 4 9   ? 127.505 66.439  79.007  1.00 127.39 ? 9   GLY E CA  1 
ATOM 4860 C C   . GLY D 4 9   ? 128.687 65.566  78.627  1.00 128.85 ? 9   GLY E C   1 
ATOM 4861 O O   . GLY D 4 9   ? 129.762 66.041  78.261  1.00 129.07 ? 9   GLY E O   1 
ATOM 4862 N N   . GLY D 4 10  ? 128.475 64.263  78.719  1.00 142.65 ? 10  GLY E N   1 
ATOM 4863 C CA  . GLY D 4 10  ? 129.511 63.308  78.388  1.00 142.74 ? 10  GLY E CA  1 
ATOM 4864 C C   . GLY D 4 10  ? 129.238 61.965  79.031  1.00 143.62 ? 10  GLY E C   1 
ATOM 4865 O O   . GLY D 4 10  ? 128.250 61.774  79.740  1.00 143.79 ? 10  GLY E O   1 
ATOM 4866 N N   . LEU D 4 11  ? 130.148 61.032  78.760  1.00 150.57 ? 11  LEU E N   1 
ATOM 4867 C CA  . LEU D 4 11  ? 130.002 59.673  79.265  1.00 150.20 ? 11  LEU E CA  1 
ATOM 4868 C C   . LEU D 4 11  ? 130.309 59.627  80.757  1.00 150.96 ? 11  LEU E C   1 
ATOM 4869 O O   . LEU D 4 11  ? 131.380 60.057  81.197  1.00 151.15 ? 11  LEU E O   1 
ATOM 4870 C CB  . LEU D 4 11  ? 130.922 58.722  78.498  1.00 149.25 ? 11  LEU E CB  1 
ATOM 4871 C CG  . LEU D 4 11  ? 130.810 57.226  78.804  1.00 149.39 ? 11  LEU E CG  1 
ATOM 4872 C CD1 . LEU D 4 11  ? 130.907 56.417  77.521  1.00 149.42 ? 11  LEU E CD1 1 
ATOM 4873 C CD2 . LEU D 4 11  ? 131.880 56.782  79.792  1.00 149.70 ? 11  LEU E CD2 1 
ATOM 4874 N N   . VAL D 4 12  ? 129.363 59.102  81.538  1.00 147.58 ? 12  VAL E N   1 
ATOM 4875 C CA  . VAL D 4 12  ? 129.504 59.001  82.983  1.00 147.03 ? 12  VAL E CA  1 
ATOM 4876 C C   . VAL D 4 12  ? 129.190 57.576  83.419  1.00 146.30 ? 12  VAL E C   1 
ATOM 4877 O O   . VAL D 4 12  ? 128.473 56.834  82.744  1.00 146.72 ? 12  VAL E O   1 
ATOM 4878 C CB  . VAL D 4 12  ? 128.595 60.000  83.732  1.00 145.62 ? 12  VAL E CB  1 
ATOM 4879 C CG1 . VAL D 4 12  ? 129.029 61.428  83.451  1.00 145.28 ? 12  VAL E CG1 1 
ATOM 4880 C CG2 . VAL D 4 12  ? 127.143 59.792  83.336  1.00 145.22 ? 12  VAL E CG2 1 
ATOM 4881 N N   . GLN D 4 13  ? 129.746 57.200  84.569  1.00 148.25 ? 13  GLN E N   1 
ATOM 4882 C CA  . GLN D 4 13  ? 129.506 55.892  85.154  1.00 148.84 ? 13  GLN E CA  1 
ATOM 4883 C C   . GLN D 4 13  ? 128.151 55.862  85.859  1.00 147.73 ? 13  GLN E C   1 
ATOM 4884 O O   . GLN D 4 13  ? 127.667 56.895  86.330  1.00 146.28 ? 13  GLN E O   1 
ATOM 4885 C CB  . GLN D 4 13  ? 130.611 55.544  86.147  1.00 148.39 ? 13  GLN E CB  1 
ATOM 4886 C CG  . GLN D 4 13  ? 132.003 55.488  85.537  1.00 149.20 ? 13  GLN E CG  1 
ATOM 4887 C CD  . GLN D 4 13  ? 132.169 54.339  84.561  1.00 149.47 ? 13  GLN E CD  1 
ATOM 4888 O OE1 . GLN D 4 13  ? 131.445 53.345  84.623  1.00 149.38 ? 13  GLN E OE1 1 
ATOM 4889 N NE2 . GLN D 4 13  ? 133.127 54.471  83.651  1.00 147.61 ? 13  GLN E NE2 1 
ATOM 4890 N N   . PRO D 4 14  ? 127.512 54.694  85.928  1.00 146.68 ? 14  PRO E N   1 
ATOM 4891 C CA  . PRO D 4 14  ? 126.246 54.594  86.665  1.00 146.32 ? 14  PRO E CA  1 
ATOM 4892 C C   . PRO D 4 14  ? 126.433 54.960  88.130  1.00 146.07 ? 14  PRO E C   1 
ATOM 4893 O O   . PRO D 4 14  ? 127.440 54.617  88.752  1.00 145.99 ? 14  PRO E O   1 
ATOM 4894 C CB  . PRO D 4 14  ? 125.852 53.122  86.498  1.00 145.77 ? 14  PRO E CB  1 
ATOM 4895 C CG  . PRO D 4 14  ? 126.569 52.674  85.269  1.00 145.41 ? 14  PRO E CG  1 
ATOM 4896 C CD  . PRO D 4 14  ? 127.862 53.431  85.256  1.00 146.82 ? 14  PRO E CD  1 
ATOM 4897 N N   . GLY D 4 15  ? 125.447 55.666  88.678  1.00 137.01 ? 15  GLY E N   1 
ATOM 4898 C CA  . GLY D 4 15  ? 125.525 56.142  90.041  1.00 135.63 ? 15  GLY E CA  1 
ATOM 4899 C C   . GLY D 4 15  ? 126.379 57.373  90.237  1.00 136.02 ? 15  GLY E C   1 
ATOM 4900 O O   . GLY D 4 15  ? 126.556 57.807  91.383  1.00 134.79 ? 15  GLY E O   1 
ATOM 4901 N N   . GLY D 4 16  ? 126.913 57.951  89.163  1.00 135.40 ? 16  GLY E N   1 
ATOM 4902 C CA  . GLY D 4 16  ? 127.774 59.110  89.252  1.00 134.54 ? 16  GLY E CA  1 
ATOM 4903 C C   . GLY D 4 16  ? 126.995 60.411  89.273  1.00 133.27 ? 16  GLY E C   1 
ATOM 4904 O O   . GLY D 4 16  ? 125.766 60.442  89.355  1.00 133.01 ? 16  GLY E O   1 
ATOM 4905 N N   . SER D 4 17  ? 127.742 61.509  89.189  1.00 129.76 ? 17  SER E N   1 
ATOM 4906 C CA  . SER D 4 17  ? 127.174 62.847  89.211  1.00 129.28 ? 17  SER E CA  1 
ATOM 4907 C C   . SER D 4 17  ? 127.754 63.667  88.068  1.00 130.45 ? 17  SER E C   1 
ATOM 4908 O O   . SER D 4 17  ? 128.917 63.503  87.691  1.00 131.94 ? 17  SER E O   1 
ATOM 4909 C CB  . SER D 4 17  ? 127.444 63.550  90.549  1.00 129.58 ? 17  SER E CB  1 
ATOM 4910 O OG  . SER D 4 17  ? 126.881 62.827  91.629  1.00 130.69 ? 17  SER E OG  1 
ATOM 4911 N N   . ARG D 4 18  ? 126.926 64.554  87.519  1.00 121.07 ? 18  ARG E N   1 
ATOM 4912 C CA  . ARG D 4 18  ? 127.341 65.418  86.425  1.00 119.49 ? 18  ARG E CA  1 
ATOM 4913 C C   . ARG D 4 18  ? 126.619 66.750  86.556  1.00 116.65 ? 18  ARG E C   1 
ATOM 4914 O O   . ARG D 4 18  ? 125.482 66.812  87.033  1.00 115.80 ? 18  ARG E O   1 
ATOM 4915 C CB  . ARG D 4 18  ? 127.064 64.781  85.058  1.00 120.36 ? 18  ARG E CB  1 
ATOM 4916 C CG  . ARG D 4 18  ? 127.873 65.386  83.923  1.00 118.92 ? 18  ARG E CG  1 
ATOM 4917 C CD  . ARG D 4 18  ? 129.363 65.320  84.232  1.00 118.89 ? 18  ARG E CD  1 
ATOM 4918 N NE  . ARG D 4 18  ? 130.177 65.942  83.194  1.00 121.97 ? 18  ARG E NE  1 
ATOM 4919 C CZ  . ARG D 4 18  ? 130.771 65.282  82.209  1.00 121.65 ? 18  ARG E CZ  1 
ATOM 4920 N NH1 . ARG D 4 18  ? 130.668 63.968  82.097  1.00 118.62 ? 18  ARG E NH1 1 
ATOM 4921 N NH2 . ARG D 4 18  ? 131.489 65.957  81.316  1.00 119.57 ? 18  ARG E NH2 1 
ATOM 4922 N N   . LYS D 4 19  ? 127.291 67.816  86.129  1.00 106.12 ? 19  LYS E N   1 
ATOM 4923 C CA  . LYS D 4 19  ? 126.789 69.178  86.257  1.00 107.66 ? 19  LYS E CA  1 
ATOM 4924 C C   . LYS D 4 19  ? 126.560 69.759  84.870  1.00 108.22 ? 19  LYS E C   1 
ATOM 4925 O O   . LYS D 4 19  ? 127.507 69.904  84.090  1.00 108.19 ? 19  LYS E O   1 
ATOM 4926 C CB  . LYS D 4 19  ? 127.769 70.046  87.049  1.00 107.46 ? 19  LYS E CB  1 
ATOM 4927 C CG  . LYS D 4 19  ? 127.306 71.474  87.268  1.00 106.50 ? 19  LYS E CG  1 
ATOM 4928 C CD  . LYS D 4 19  ? 126.073 71.514  88.154  1.00 106.33 ? 19  LYS E CD  1 
ATOM 4929 C CE  . LYS D 4 19  ? 125.766 72.927  88.610  1.00 105.42 ? 19  LYS E CE  1 
ATOM 4930 N NZ  . LYS D 4 19  ? 126.894 73.518  89.382  1.00 107.12 ? 19  LYS E NZ  1 
ATOM 4931 N N   . LEU D 4 20  ? 125.308 70.091  84.569  1.00 100.69 ? 20  LEU E N   1 
ATOM 4932 C CA  . LEU D 4 20  ? 124.937 70.690  83.296  1.00 100.66 ? 20  LEU E CA  1 
ATOM 4933 C C   . LEU D 4 20  ? 124.807 72.199  83.449  1.00 99.26  ? 20  LEU E C   1 
ATOM 4934 O O   . LEU D 4 20  ? 124.256 72.690  84.439  1.00 97.87  ? 20  LEU E O   1 
ATOM 4935 C CB  . LEU D 4 20  ? 123.623 70.104  82.777  1.00 99.24  ? 20  LEU E CB  1 
ATOM 4936 C CG  . LEU D 4 20  ? 123.654 68.625  82.393  1.00 96.86  ? 20  LEU E CG  1 
ATOM 4937 C CD1 . LEU D 4 20  ? 122.294 68.176  81.884  1.00 96.00  ? 20  LEU E CD1 1 
ATOM 4938 C CD2 . LEU D 4 20  ? 124.734 68.360  81.358  1.00 98.35  ? 20  LEU E CD2 1 
ATOM 4939 N N   . SER D 4 21  ? 125.318 72.929  82.462  1.00 102.35 ? 21  SER E N   1 
ATOM 4940 C CA  . SER D 4 21  ? 125.286 74.384  82.453  1.00 102.94 ? 21  SER E CA  1 
ATOM 4941 C C   . SER D 4 21  ? 124.546 74.883  81.221  1.00 103.33 ? 21  SER E C   1 
ATOM 4942 O O   . SER D 4 21  ? 124.625 74.275  80.148  1.00 102.12 ? 21  SER E O   1 
ATOM 4943 C CB  . SER D 4 21  ? 126.702 74.967  82.479  1.00 102.81 ? 21  SER E CB  1 
ATOM 4944 O OG  . SER D 4 21  ? 127.402 74.558  83.640  1.00 105.34 ? 21  SER E OG  1 
ATOM 4945 N N   . CYS D 4 22  ? 123.823 75.989  81.382  1.00 97.95  ? 22  CYS E N   1 
ATOM 4946 C CA  . CYS D 4 22  ? 123.127 76.646  80.280  1.00 96.83  ? 22  CYS E CA  1 
ATOM 4947 C C   . CYS D 4 22  ? 123.476 78.126  80.317  1.00 99.91  ? 22  CYS E C   1 
ATOM 4948 O O   . CYS D 4 22  ? 122.978 78.864  81.174  1.00 100.20 ? 22  CYS E O   1 
ATOM 4949 C CB  . CYS D 4 22  ? 121.615 76.436  80.375  1.00 96.51  ? 22  CYS E CB  1 
ATOM 4950 S SG  . CYS D 4 22  ? 120.648 77.458  79.239  1.00 103.24 ? 22  CYS E SG  1 
ATOM 4951 N N   . SER D 4 23  ? 124.328 78.558  79.390  1.00 104.17 ? 23  SER E N   1 
ATOM 4952 C CA  . SER D 4 23  ? 124.736 79.952  79.299  1.00 102.16 ? 23  SER E CA  1 
ATOM 4953 C C   . SER D 4 23  ? 123.802 80.701  78.359  1.00 99.50  ? 23  SER E C   1 
ATOM 4954 O O   . SER D 4 23  ? 123.556 80.258  77.233  1.00 98.59  ? 23  SER E O   1 
ATOM 4955 C CB  . SER D 4 23  ? 126.181 80.059  78.809  1.00 100.12 ? 23  SER E CB  1 
ATOM 4956 O OG  . SER D 4 23  ? 127.063 79.360  79.670  1.00 100.68 ? 23  SER E OG  1 
ATOM 4957 N N   . ALA D 4 24  ? 123.282 81.832  78.826  1.00 89.16  ? 24  ALA E N   1 
ATOM 4958 C CA  . ALA D 4 24  ? 122.322 82.625  78.076  1.00 85.29  ? 24  ALA E CA  1 
ATOM 4959 C C   . ALA D 4 24  ? 122.964 83.923  77.609  1.00 92.46  ? 24  ALA E C   1 
ATOM 4960 O O   . ALA D 4 24  ? 123.659 84.596  78.378  1.00 98.83  ? 24  ALA E O   1 
ATOM 4961 C CB  . ALA D 4 24  ? 121.087 82.931  78.925  1.00 84.98  ? 24  ALA E CB  1 
ATOM 4962 N N   . SER D 4 25  ? 122.728 84.270  76.346  1.00 87.90  ? 25  SER E N   1 
ATOM 4963 C CA  . SER D 4 25  ? 123.207 85.521  75.782  1.00 87.03  ? 25  SER E CA  1 
ATOM 4964 C C   . SER D 4 25  ? 122.148 86.087  74.849  1.00 85.26  ? 25  SER E C   1 
ATOM 4965 O O   . SER D 4 25  ? 121.378 85.345  74.234  1.00 85.08  ? 25  SER E O   1 
ATOM 4966 C CB  . SER D 4 25  ? 124.529 85.334  75.026  1.00 87.30  ? 25  SER E CB  1 
ATOM 4967 O OG  . SER D 4 25  ? 124.381 84.414  73.960  1.00 84.85  ? 25  SER E OG  1 
ATOM 4968 N N   . GLY D 4 26  ? 122.117 87.412  74.750  1.00 80.74  ? 26  GLY E N   1 
ATOM 4969 C CA  . GLY D 4 26  ? 121.227 88.083  73.829  1.00 83.51  ? 26  GLY E CA  1 
ATOM 4970 C C   . GLY D 4 26  ? 119.835 88.362  74.347  1.00 77.84  ? 26  GLY E C   1 
ATOM 4971 O O   . GLY D 4 26  ? 118.987 88.815  73.569  1.00 77.62  ? 26  GLY E O   1 
ATOM 4972 N N   . PHE D 4 27  ? 119.563 88.099  75.623  1.00 66.47  ? 27  PHE E N   1 
ATOM 4973 C CA  . PHE D 4 27  ? 118.268 88.435  76.195  1.00 68.50  ? 27  PHE E CA  1 
ATOM 4974 C C   . PHE D 4 27  ? 118.422 88.614  77.697  1.00 77.19  ? 27  PHE E C   1 
ATOM 4975 O O   . PHE D 4 27  ? 119.426 88.211  78.290  1.00 81.46  ? 27  PHE E O   1 
ATOM 4976 C CB  . PHE D 4 27  ? 117.211 87.369  75.875  1.00 74.57  ? 27  PHE E CB  1 
ATOM 4977 C CG  . PHE D 4 27  ? 117.412 86.067  76.598  1.00 73.53  ? 27  PHE E CG  1 
ATOM 4978 C CD1 . PHE D 4 27  ? 118.308 85.125  76.124  1.00 74.49  ? 27  PHE E CD1 1 
ATOM 4979 C CD2 . PHE D 4 27  ? 116.688 85.778  77.744  1.00 71.71  ? 27  PHE E CD2 1 
ATOM 4980 C CE1 . PHE D 4 27  ? 118.486 83.927  76.784  1.00 74.53  ? 27  PHE E CE1 1 
ATOM 4981 C CE2 . PHE D 4 27  ? 116.863 84.582  78.408  1.00 70.26  ? 27  PHE E CE2 1 
ATOM 4982 C CZ  . PHE D 4 27  ? 117.763 83.656  77.927  1.00 72.57  ? 27  PHE E CZ  1 
ATOM 4983 N N   . ALA D 4 28  ? 117.409 89.231  78.304  1.00 77.28  ? 28  ALA E N   1 
ATOM 4984 C CA  . ALA D 4 28  ? 117.408 89.488  79.739  1.00 78.58  ? 28  ALA E CA  1 
ATOM 4985 C C   . ALA D 4 28  ? 117.191 88.198  80.518  1.00 79.97  ? 28  ALA E C   1 
ATOM 4986 O O   . ALA D 4 28  ? 116.047 87.805  80.769  1.00 79.91  ? 28  ALA E O   1 
ATOM 4987 C CB  . ALA D 4 28  ? 116.335 90.518  80.098  1.00 74.14  ? 28  ALA E CB  1 
ATOM 4988 N N   . PHE D 4 29  ? 118.284 87.534  80.905  1.00 70.19  ? 29  PHE E N   1 
ATOM 4989 C CA  . PHE D 4 29  ? 118.181 86.207  81.506  1.00 69.31  ? 29  PHE E CA  1 
ATOM 4990 C C   . PHE D 4 29  ? 117.410 86.241  82.820  1.00 65.19  ? 29  PHE E C   1 
ATOM 4991 O O   . PHE D 4 29  ? 116.604 85.345  83.097  1.00 63.38  ? 29  PHE E O   1 
ATOM 4992 C CB  . PHE D 4 29  ? 119.574 85.616  81.721  1.00 68.30  ? 29  PHE E CB  1 
ATOM 4993 C CG  . PHE D 4 29  ? 119.565 84.284  82.417  1.00 67.28  ? 29  PHE E CG  1 
ATOM 4994 C CD1 . PHE D 4 29  ? 119.062 83.159  81.786  1.00 68.93  ? 29  PHE E CD1 1 
ATOM 4995 C CD2 . PHE D 4 29  ? 120.065 84.156  83.702  1.00 64.58  ? 29  PHE E CD2 1 
ATOM 4996 C CE1 . PHE D 4 29  ? 119.055 81.934  82.424  1.00 68.77  ? 29  PHE E CE1 1 
ATOM 4997 C CE2 . PHE D 4 29  ? 120.061 82.934  84.344  1.00 67.23  ? 29  PHE E CE2 1 
ATOM 4998 C CZ  . PHE D 4 29  ? 119.556 81.823  83.704  1.00 69.85  ? 29  PHE E CZ  1 
ATOM 4999 N N   . SER D 4 30  ? 117.645 87.262  83.647  1.00 63.21  ? 30  SER E N   1 
ATOM 5000 C CA  . SER D 4 30  ? 116.993 87.324  84.951  1.00 67.98  ? 30  SER E CA  1 
ATOM 5001 C C   . SER D 4 30  ? 115.487 87.534  84.846  1.00 69.00  ? 30  SER E C   1 
ATOM 5002 O O   . SER D 4 30  ? 114.772 87.277  85.820  1.00 71.75  ? 30  SER E O   1 
ATOM 5003 C CB  . SER D 4 30  ? 117.616 88.435  85.799  1.00 63.88  ? 30  SER E CB  1 
ATOM 5004 O OG  . SER D 4 30  ? 117.474 89.699  85.174  1.00 71.00  ? 30  SER E OG  1 
ATOM 5005 N N   . SER D 4 31  ? 114.991 87.990  83.697  1.00 62.06  ? 31  SER E N   1 
ATOM 5006 C CA  . SER D 4 31  ? 113.565 88.215  83.505  1.00 59.43  ? 31  SER E CA  1 
ATOM 5007 C C   . SER D 4 31  ? 112.815 86.969  83.049  1.00 60.37  ? 31  SER E C   1 
ATOM 5008 O O   . SER D 4 31  ? 111.579 86.968  83.071  1.00 65.03  ? 31  SER E O   1 
ATOM 5009 C CB  . SER D 4 31  ? 113.338 89.342  82.490  1.00 60.15  ? 31  SER E CB  1 
ATOM 5010 O OG  . SER D 4 31  ? 113.893 90.562  82.948  1.00 63.91  ? 31  SER E OG  1 
ATOM 5011 N N   . PHE D 4 32  ? 113.521 85.919  82.638  1.00 54.71  ? 32  PHE E N   1 
ATOM 5012 C CA  . PHE D 4 32  ? 112.905 84.724  82.077  1.00 52.49  ? 32  PHE E CA  1 
ATOM 5013 C C   . PHE D 4 32  ? 112.971 83.570  83.067  1.00 53.68  ? 32  PHE E C   1 
ATOM 5014 O O   . PHE D 4 32  ? 114.006 83.340  83.701  1.00 59.35  ? 32  PHE E O   1 
ATOM 5015 C CB  . PHE D 4 32  ? 113.595 84.309  80.772  1.00 58.52  ? 32  PHE E CB  1 
ATOM 5016 C CG  . PHE D 4 32  ? 113.200 85.133  79.581  1.00 56.33  ? 32  PHE E CG  1 
ATOM 5017 C CD1 . PHE D 4 32  ? 113.678 86.420  79.423  1.00 55.77  ? 32  PHE E CD1 1 
ATOM 5018 C CD2 . PHE D 4 32  ? 112.362 84.612  78.610  1.00 60.06  ? 32  PHE E CD2 1 
ATOM 5019 C CE1 . PHE D 4 32  ? 113.322 87.175  78.328  1.00 56.10  ? 32  PHE E CE1 1 
ATOM 5020 C CE2 . PHE D 4 32  ? 112.002 85.364  77.511  1.00 57.08  ? 32  PHE E CE2 1 
ATOM 5021 C CZ  . PHE D 4 32  ? 112.482 86.647  77.370  1.00 55.19  ? 32  PHE E CZ  1 
ATOM 5022 N N   . GLY D 4 33  ? 111.860 82.851  83.197  1.00 41.84  ? 33  GLY E N   1 
ATOM 5023 C CA  . GLY D 4 33  ? 111.911 81.533  83.796  1.00 34.98  ? 33  GLY E CA  1 
ATOM 5024 C C   . GLY D 4 33  ? 112.592 80.541  82.874  1.00 33.09  ? 33  GLY E C   1 
ATOM 5025 O O   . GLY D 4 33  ? 112.584 80.683  81.651  1.00 50.95  ? 33  GLY E O   1 
ATOM 5026 N N   . MET D 4 34  ? 113.192 79.517  83.472  1.00 28.80  ? 34  MET E N   1 
ATOM 5027 C CA  . MET D 4 34  ? 113.988 78.551  82.730  1.00 42.24  ? 34  MET E CA  1 
ATOM 5028 C C   . MET D 4 34  ? 113.525 77.133  83.032  1.00 39.11  ? 34  MET E C   1 
ATOM 5029 O O   . MET D 4 34  ? 113.221 76.801  84.182  1.00 43.45  ? 34  MET E O   1 
ATOM 5030 C CB  . MET D 4 34  ? 115.474 78.699  83.064  1.00 41.44  ? 34  MET E CB  1 
ATOM 5031 C CG  . MET D 4 34  ? 116.020 80.104  82.863  1.00 44.54  ? 34  MET E CG  1 
ATOM 5032 S SD  . MET D 4 34  ? 115.809 80.710  81.178  1.00 48.29  ? 34  MET E SD  1 
ATOM 5033 C CE  . MET D 4 34  ? 116.809 79.537  80.268  1.00 44.25  ? 34  MET E CE  1 
ATOM 5034 N N   . HIS D 4 35  ? 113.477 76.302  81.993  1.00 36.64  ? 35  HIS E N   1 
ATOM 5035 C CA  . HIS D 4 35  ? 113.135 74.894  82.117  1.00 27.65  ? 35  HIS E CA  1 
ATOM 5036 C C   . HIS D 4 35  ? 114.280 74.036  81.596  1.00 47.13  ? 35  HIS E C   1 
ATOM 5037 O O   . HIS D 4 35  ? 115.019 74.440  80.693  1.00 60.76  ? 35  HIS E O   1 
ATOM 5038 C CB  . HIS D 4 35  ? 111.859 74.545  81.338  1.00 33.67  ? 35  HIS E CB  1 
ATOM 5039 C CG  . HIS D 4 35  ? 110.680 75.397  81.683  1.00 30.50  ? 35  HIS E CG  1 
ATOM 5040 N ND1 . HIS D 4 35  ? 109.631 74.940  82.450  1.00 41.79  ? 35  HIS E ND1 1 
ATOM 5041 C CD2 . HIS D 4 35  ? 110.380 76.676  81.361  1.00 30.75  ? 35  HIS E CD2 1 
ATOM 5042 C CE1 . HIS D 4 35  ? 108.735 75.901  82.585  1.00 36.87  ? 35  HIS E CE1 1 
ATOM 5043 N NE2 . HIS D 4 35  ? 109.166 76.967  81.936  1.00 16.02  ? 35  HIS E NE2 1 
ATOM 5044 N N   . TRP D 4 36  ? 114.420 72.849  82.176  1.00 63.62  ? 36  TRP E N   1 
ATOM 5045 C CA  . TRP D 4 36  ? 115.221 71.778  81.600  1.00 63.38  ? 36  TRP E CA  1 
ATOM 5046 C C   . TRP D 4 36  ? 114.305 70.707  81.025  1.00 65.21  ? 36  TRP E C   1 
ATOM 5047 O O   . TRP D 4 36  ? 113.435 70.186  81.730  1.00 71.86  ? 36  TRP E O   1 
ATOM 5048 C CB  . TRP D 4 36  ? 116.158 71.166  82.642  1.00 70.16  ? 36  TRP E CB  1 
ATOM 5049 C CG  . TRP D 4 36  ? 117.332 72.024  82.967  1.00 65.23  ? 36  TRP E CG  1 
ATOM 5050 C CD1 . TRP D 4 36  ? 117.444 72.909  83.998  1.00 67.62  ? 36  TRP E CD1 1 
ATOM 5051 C CD2 . TRP D 4 36  ? 118.566 72.087  82.246  1.00 58.53  ? 36  TRP E CD2 1 
ATOM 5052 N NE1 . TRP D 4 36  ? 118.677 73.515  83.968  1.00 65.50  ? 36  TRP E NE1 1 
ATOM 5053 C CE2 . TRP D 4 36  ? 119.384 73.028  82.900  1.00 65.05  ? 36  TRP E CE2 1 
ATOM 5054 C CE3 . TRP D 4 36  ? 119.060 71.436  81.111  1.00 67.13  ? 36  TRP E CE3 1 
ATOM 5055 C CZ2 . TRP D 4 36  ? 120.669 73.335  82.459  1.00 72.13  ? 36  TRP E CZ2 1 
ATOM 5056 C CZ3 . TRP D 4 36  ? 120.334 71.741  80.674  1.00 71.91  ? 36  TRP E CZ3 1 
ATOM 5057 C CH2 . TRP D 4 36  ? 121.124 72.682  81.346  1.00 73.71  ? 36  TRP E CH2 1 
ATOM 5058 N N   . VAL D 4 37  ? 114.500 70.388  79.748  1.00 70.40  ? 37  VAL E N   1 
ATOM 5059 C CA  . VAL D 4 37  ? 113.774 69.315  79.079  1.00 74.54  ? 37  VAL E CA  1 
ATOM 5060 C C   . VAL D 4 37  ? 114.790 68.365  78.462  1.00 79.83  ? 37  VAL E C   1 
ATOM 5061 O O   . VAL D 4 37  ? 115.714 68.804  77.769  1.00 75.64  ? 37  VAL E O   1 
ATOM 5062 C CB  . VAL D 4 37  ? 112.809 69.855  78.006  1.00 69.42  ? 37  VAL E CB  1 
ATOM 5063 C CG1 . VAL D 4 37  ? 112.110 68.709  77.295  1.00 74.31  ? 37  VAL E CG1 1 
ATOM 5064 C CG2 . VAL D 4 37  ? 111.787 70.788  78.638  1.00 63.76  ? 37  VAL E CG2 1 
ATOM 5065 N N   . ARG D 4 38  ? 114.619 67.069  78.706  1.00 91.54  ? 38  ARG E N   1 
ATOM 5066 C CA  . ARG D 4 38  ? 115.504 66.058  78.152  1.00 86.70  ? 38  ARG E CA  1 
ATOM 5067 C C   . ARG D 4 38  ? 114.754 65.178  77.161  1.00 88.49  ? 38  ARG E C   1 
ATOM 5068 O O   . ARG D 4 38  ? 113.522 65.102  77.166  1.00 90.25  ? 38  ARG E O   1 
ATOM 5069 C CB  . ARG D 4 38  ? 116.125 65.195  79.258  1.00 88.21  ? 38  ARG E CB  1 
ATOM 5070 C CG  . ARG D 4 38  ? 115.152 64.273  79.982  1.00 89.29  ? 38  ARG E CG  1 
ATOM 5071 C CD  . ARG D 4 38  ? 115.911 63.206  80.764  1.00 92.65  ? 38  ARG E CD  1 
ATOM 5072 N NE  . ARG D 4 38  ? 115.040 62.375  81.588  1.00 90.41  ? 38  ARG E NE  1 
ATOM 5073 C CZ  . ARG D 4 38  ? 114.864 62.538  82.892  1.00 89.02  ? 38  ARG E CZ  1 
ATOM 5074 N NH1 . ARG D 4 38  ? 115.479 63.502  83.558  1.00 90.84  ? 38  ARG E NH1 1 
ATOM 5075 N NH2 . ARG D 4 38  ? 114.055 61.709  83.546  1.00 87.88  ? 38  ARG E NH2 1 
ATOM 5076 N N   . GLN D 4 39  ? 115.521 64.510  76.302  1.00 101.34 ? 39  GLN E N   1 
ATOM 5077 C CA  . GLN D 4 39  ? 114.967 63.634  75.273  1.00 103.05 ? 39  GLN E CA  1 
ATOM 5078 C C   . GLN D 4 39  ? 115.836 62.388  75.183  1.00 103.91 ? 39  GLN E C   1 
ATOM 5079 O O   . GLN D 4 39  ? 116.988 62.465  74.745  1.00 105.21 ? 39  GLN E O   1 
ATOM 5080 C CB  . GLN D 4 39  ? 114.891 64.347  73.924  1.00 103.05 ? 39  GLN E CB  1 
ATOM 5081 C CG  . GLN D 4 39  ? 114.222 63.538  72.827  1.00 102.32 ? 39  GLN E CG  1 
ATOM 5082 C CD  . GLN D 4 39  ? 114.258 64.241  71.485  1.00 104.73 ? 39  GLN E CD  1 
ATOM 5083 O OE1 . GLN D 4 39  ? 115.147 65.049  71.219  1.00 106.63 ? 39  GLN E OE1 1 
ATOM 5084 N NE2 . GLN D 4 39  ? 113.287 63.938  70.632  1.00 103.24 ? 39  GLN E NE2 1 
ATOM 5085 N N   . ALA D 4 40  ? 115.289 61.247  75.595  1.00 110.65 ? 40  ALA E N   1 
ATOM 5086 C CA  . ALA D 4 40  ? 116.020 59.997  75.498  1.00 111.48 ? 40  ALA E CA  1 
ATOM 5087 C C   . ALA D 4 40  ? 116.229 59.619  74.032  1.00 113.02 ? 40  ALA E C   1 
ATOM 5088 O O   . ALA D 4 40  ? 115.412 59.963  73.173  1.00 112.60 ? 40  ALA E O   1 
ATOM 5089 C CB  . ALA D 4 40  ? 115.273 58.882  76.225  1.00 109.86 ? 40  ALA E CB  1 
ATOM 5090 N N   . PRO D 4 41  ? 117.331 58.937  73.717  1.00 113.79 ? 41  PRO E N   1 
ATOM 5091 C CA  . PRO D 4 41  ? 117.592 58.553  72.323  1.00 111.99 ? 41  PRO E CA  1 
ATOM 5092 C C   . PRO D 4 41  ? 116.449 57.730  71.746  1.00 114.36 ? 41  PRO E C   1 
ATOM 5093 O O   . PRO D 4 41  ? 115.984 56.766  72.358  1.00 114.92 ? 41  PRO E O   1 
ATOM 5094 C CB  . PRO D 4 41  ? 118.887 57.738  72.418  1.00 110.91 ? 41  PRO E CB  1 
ATOM 5095 C CG  . PRO D 4 41  ? 119.556 58.248  73.649  1.00 111.33 ? 41  PRO E CG  1 
ATOM 5096 C CD  . PRO D 4 41  ? 118.445 58.569  74.608  1.00 112.54 ? 41  PRO E CD  1 
ATOM 5097 N N   . GLU D 4 42  ? 116.001 58.127  70.553  1.00 114.65 ? 42  GLU E N   1 
ATOM 5098 C CA  . GLU D 4 42  ? 114.861 57.502  69.877  1.00 114.26 ? 42  GLU E CA  1 
ATOM 5099 C C   . GLU D 4 42  ? 113.618 57.504  70.764  1.00 115.35 ? 42  GLU E C   1 
ATOM 5100 O O   . GLU D 4 42  ? 112.831 56.555  70.768  1.00 115.53 ? 42  GLU E O   1 
ATOM 5101 C CB  . GLU D 4 42  ? 115.201 56.081  69.419  1.00 114.22 ? 42  GLU E CB  1 
ATOM 5102 C CG  . GLU D 4 42  ? 116.458 55.983  68.569  1.00 115.15 ? 42  GLU E CG  1 
ATOM 5103 C CD  . GLU D 4 42  ? 116.312 56.675  67.226  1.00 117.06 ? 42  GLU E CD  1 
ATOM 5104 O OE1 . GLU D 4 42  ? 115.169 56.800  66.739  1.00 118.33 ? 42  GLU E OE1 1 
ATOM 5105 O OE2 . GLU D 4 42  ? 117.342 57.094  66.658  1.00 118.17 ? 42  GLU E OE2 1 
ATOM 5106 N N   . LYS D 4 43  ? 113.437 58.586  71.521  1.00 105.87 ? 43  LYS E N   1 
ATOM 5107 C CA  . LYS D 4 43  ? 112.284 58.760  72.391  1.00 102.50 ? 43  LYS E CA  1 
ATOM 5108 C C   . LYS D 4 43  ? 111.835 60.213  72.319  1.00 101.19 ? 43  LYS E C   1 
ATOM 5109 O O   . LYS D 4 43  ? 112.437 61.039  71.625  1.00 104.38 ? 43  LYS E O   1 
ATOM 5110 C CB  . LYS D 4 43  ? 112.602 58.353  73.836  1.00 101.20 ? 43  LYS E CB  1 
ATOM 5111 C CG  . LYS D 4 43  ? 112.855 56.866  74.037  1.00 102.84 ? 43  LYS E CG  1 
ATOM 5112 C CD  . LYS D 4 43  ? 111.609 56.048  73.743  1.00 103.67 ? 43  LYS E CD  1 
ATOM 5113 C CE  . LYS D 4 43  ? 111.867 54.562  73.935  1.00 104.55 ? 43  LYS E CE  1 
ATOM 5114 N NZ  . LYS D 4 43  ? 112.949 54.065  73.041  1.00 104.98 ? 43  LYS E NZ  1 
ATOM 5115 N N   . GLY D 4 44  ? 110.762 60.525  73.043  1.00 91.89  ? 44  GLY E N   1 
ATOM 5116 C CA  . GLY D 4 44  ? 110.205 61.859  73.065  1.00 93.87  ? 44  GLY E CA  1 
ATOM 5117 C C   . GLY D 4 44  ? 110.837 62.741  74.125  1.00 96.45  ? 44  GLY E C   1 
ATOM 5118 O O   . GLY D 4 44  ? 111.795 62.370  74.806  1.00 98.13  ? 44  GLY E O   1 
ATOM 5119 N N   . LEU D 4 45  ? 110.276 63.940  74.259  1.00 84.55  ? 45  LEU E N   1 
ATOM 5120 C CA  . LEU D 4 45  ? 110.789 64.931  75.191  1.00 80.59  ? 45  LEU E CA  1 
ATOM 5121 C C   . LEU D 4 45  ? 110.292 64.639  76.601  1.00 81.98  ? 45  LEU E C   1 
ATOM 5122 O O   . LEU D 4 45  ? 109.190 64.120  76.799  1.00 84.27  ? 45  LEU E O   1 
ATOM 5123 C CB  . LEU D 4 45  ? 110.364 66.338  74.770  1.00 81.92  ? 45  LEU E CB  1 
ATOM 5124 C CG  . LEU D 4 45  ? 110.740 66.777  73.353  1.00 79.05  ? 45  LEU E CG  1 
ATOM 5125 C CD1 . LEU D 4 45  ? 110.167 68.151  73.049  1.00 78.21  ? 45  LEU E CD1 1 
ATOM 5126 C CD2 . LEU D 4 45  ? 112.248 66.776  73.174  1.00 80.88  ? 45  LEU E CD2 1 
ATOM 5127 N N   . GLU D 4 46  ? 111.122 64.968  77.588  1.00 86.60  ? 46  GLU E N   1 
ATOM 5128 C CA  . GLU D 4 46  ? 110.773 64.756  78.989  1.00 89.42  ? 46  GLU E CA  1 
ATOM 5129 C C   . GLU D 4 46  ? 111.223 65.959  79.801  1.00 89.52  ? 46  GLU E C   1 
ATOM 5130 O O   . GLU D 4 46  ? 112.412 66.292  79.815  1.00 88.15  ? 46  GLU E O   1 
ATOM 5131 C CB  . GLU D 4 46  ? 111.410 63.472  79.529  1.00 89.35  ? 46  GLU E CB  1 
ATOM 5132 C CG  . GLU D 4 46  ? 111.090 63.190  80.987  1.00 89.37  ? 46  GLU E CG  1 
ATOM 5133 C CD  . GLU D 4 46  ? 111.694 61.888  81.468  1.00 92.72  ? 46  GLU E CD  1 
ATOM 5134 O OE1 . GLU D 4 46  ? 112.240 61.142  80.630  1.00 93.86  ? 46  GLU E OE1 1 
ATOM 5135 O OE2 . GLU D 4 46  ? 111.622 61.608  82.683  1.00 90.11  ? 46  GLU E OE2 1 
ATOM 5136 N N   . TRP D 4 47  ? 110.274 66.602  80.475  1.00 78.48  ? 47  TRP E N   1 
ATOM 5137 C CA  . TRP D 4 47  ? 110.577 67.774  81.286  1.00 72.84  ? 47  TRP E CA  1 
ATOM 5138 C C   . TRP D 4 47  ? 111.293 67.365  82.568  1.00 66.90  ? 47  TRP E C   1 
ATOM 5139 O O   . TRP D 4 47  ? 110.934 66.374  83.211  1.00 72.05  ? 47  TRP E O   1 
ATOM 5140 C CB  . TRP D 4 47  ? 109.289 68.533  81.607  1.00 69.89  ? 47  TRP E CB  1 
ATOM 5141 C CG  . TRP D 4 47  ? 109.464 69.651  82.585  1.00 67.48  ? 47  TRP E CG  1 
ATOM 5142 C CD1 . TRP D 4 47  ? 110.115 70.830  82.374  1.00 77.13  ? 47  TRP E CD1 1 
ATOM 5143 C CD2 . TRP D 4 47  ? 108.961 69.705  83.924  1.00 63.72  ? 47  TRP E CD2 1 
ATOM 5144 N NE1 . TRP D 4 47  ? 110.062 71.610  83.503  1.00 71.56  ? 47  TRP E NE1 1 
ATOM 5145 C CE2 . TRP D 4 47  ? 109.357 70.942  84.469  1.00 60.99  ? 47  TRP E CE2 1 
ATOM 5146 C CE3 . TRP D 4 47  ? 108.220 68.825  84.717  1.00 75.55  ? 47  TRP E CE3 1 
ATOM 5147 C CZ2 . TRP D 4 47  ? 109.037 71.320  85.770  1.00 63.69  ? 47  TRP E CZ2 1 
ATOM 5148 C CZ3 . TRP D 4 47  ? 107.903 69.202  86.009  1.00 75.60  ? 47  TRP E CZ3 1 
ATOM 5149 C CH2 . TRP D 4 47  ? 108.311 70.439  86.522  1.00 74.46  ? 47  TRP E CH2 1 
ATOM 5150 N N   . VAL D 4 48  ? 112.313 68.138  82.942  1.00 56.52  ? 48  VAL E N   1 
ATOM 5151 C CA  . VAL D 4 48  ? 113.182 67.813  84.073  1.00 59.99  ? 48  VAL E CA  1 
ATOM 5152 C C   . VAL D 4 48  ? 112.905 68.720  85.272  1.00 67.47  ? 48  VAL E C   1 
ATOM 5153 O O   . VAL D 4 48  ? 112.590 68.240  86.362  1.00 75.34  ? 48  VAL E O   1 
ATOM 5154 C CB  . VAL D 4 48  ? 114.670 67.869  83.663  1.00 66.92  ? 48  VAL E CB  1 
ATOM 5155 C CG1 . VAL D 4 48  ? 115.564 67.608  84.868  1.00 70.64  ? 48  VAL E CG1 1 
ATOM 5156 C CG2 . VAL D 4 48  ? 114.952 66.871  82.554  1.00 68.05  ? 48  VAL E CG2 1 
ATOM 5157 N N   . ALA D 4 49  ? 113.018 70.034  85.090  1.00 59.26  ? 49  ALA E N   1 
ATOM 5158 C CA  . ALA D 4 49  ? 112.934 70.951  86.217  1.00 55.79  ? 49  ALA E CA  1 
ATOM 5159 C C   . ALA D 4 49  ? 112.479 72.320  85.732  1.00 57.14  ? 49  ALA E C   1 
ATOM 5160 O O   . ALA D 4 49  ? 112.485 72.616  84.535  1.00 67.53  ? 49  ALA E O   1 
ATOM 5161 C CB  . ALA D 4 49  ? 114.274 71.056  86.952  1.00 58.64  ? 49  ALA E CB  1 
ATOM 5162 N N   . TYR D 4 50  ? 112.081 73.157  86.688  1.00 41.52  ? 50  TYR E N   1 
ATOM 5163 C CA  . TYR D 4 50  ? 111.655 74.521  86.409  1.00 40.20  ? 50  TYR E CA  1 
ATOM 5164 C C   . TYR D 4 50  ? 112.079 75.422  87.559  1.00 39.82  ? 50  TYR E C   1 
ATOM 5165 O O   . TYR D 4 50  ? 111.908 75.067  88.728  1.00 63.06  ? 50  TYR E O   1 
ATOM 5166 C CB  . TYR D 4 50  ? 110.139 74.596  86.200  1.00 39.86  ? 50  TYR E CB  1 
ATOM 5167 C CG  . TYR D 4 50  ? 109.566 75.988  86.321  1.00 29.92  ? 50  TYR E CG  1 
ATOM 5168 C CD1 . TYR D 4 50  ? 109.932 76.991  85.439  1.00 47.38  ? 50  TYR E CD1 1 
ATOM 5169 C CD2 . TYR D 4 50  ? 108.648 76.295  87.313  1.00 35.98  ? 50  TYR E CD2 1 
ATOM 5170 C CE1 . TYR D 4 50  ? 109.407 78.263  85.545  1.00 49.97  ? 50  TYR E CE1 1 
ATOM 5171 C CE2 . TYR D 4 50  ? 108.118 77.563  87.427  1.00 38.37  ? 50  TYR E CE2 1 
ATOM 5172 C CZ  . TYR D 4 50  ? 108.499 78.543  86.540  1.00 39.68  ? 50  TYR E CZ  1 
ATOM 5173 O OH  . TYR D 4 50  ? 107.973 79.809  86.648  1.00 38.69  ? 50  TYR E OH  1 
ATOM 5174 N N   . ILE D 4 51  ? 112.628 76.587  87.220  1.00 24.50  ? 51  ILE E N   1 
ATOM 5175 C CA  . ILE D 4 51  ? 112.896 77.649  88.182  1.00 36.07  ? 51  ILE E CA  1 
ATOM 5176 C C   . ILE D 4 51  ? 112.253 78.932  87.671  1.00 30.63  ? 51  ILE E C   1 
ATOM 5177 O O   . ILE D 4 51  ? 112.399 79.282  86.495  1.00 45.29  ? 51  ILE E O   1 
ATOM 5178 C CB  . ILE D 4 51  ? 114.408 77.838  88.427  1.00 39.44  ? 51  ILE E CB  1 
ATOM 5179 C CG1 . ILE D 4 51  ? 114.657 78.951  89.447  1.00 35.78  ? 51  ILE E CG1 1 
ATOM 5180 C CG2 . ILE D 4 51  ? 115.155 78.102  87.122  1.00 43.52  ? 51  ILE E CG2 1 
ATOM 5181 C CD1 . ILE D 4 51  ? 116.074 78.986  89.975  1.00 36.18  ? 51  ILE E CD1 1 
ATOM 5182 N N   . SER D 4 52  ? 111.515 79.613  88.544  1.00 33.89  ? 52  SER E N   1 
ATOM 5183 C CA  . SER D 4 52  ? 110.762 80.792  88.149  1.00 37.65  ? 52  SER E CA  1 
ATOM 5184 C C   . SER D 4 52  ? 111.670 82.018  88.080  1.00 45.51  ? 52  SER E C   1 
ATOM 5185 O O   . SER D 4 52  ? 112.820 82.007  88.527  1.00 54.05  ? 52  SER E O   1 
ATOM 5186 C CB  . SER D 4 52  ? 109.611 81.045  89.122  1.00 46.68  ? 52  SER E CB  1 
ATOM 5187 O OG  . SER D 4 52  ? 110.097 81.332  90.421  1.00 48.22  ? 52  SER E OG  1 
ATOM 5188 N N   . SER D 4 53  ? 111.132 83.090  87.501  1.00 54.05  ? 53  SER E N   1 
ATOM 5189 C CA  . SER D 4 53  ? 111.798 84.385  87.550  1.00 45.93  ? 53  SER E CA  1 
ATOM 5190 C C   . SER D 4 53  ? 111.920 84.863  88.992  1.00 59.57  ? 53  SER E C   1 
ATOM 5191 O O   . SER D 4 53  ? 110.943 84.858  89.746  1.00 59.28  ? 53  SER E O   1 
ATOM 5192 C CB  . SER D 4 53  ? 111.024 85.404  86.713  1.00 35.69  ? 53  SER E CB  1 
ATOM 5193 O OG  . SER D 4 53  ? 111.631 86.682  86.777  1.00 45.25  ? 53  SER E OG  1 
ATOM 5194 N N   . GLY D 4 54  ? 113.125 85.282  89.372  1.00 64.56  ? 54  GLY E N   1 
ATOM 5195 C CA  . GLY D 4 54  ? 113.410 85.641  90.745  1.00 62.00  ? 54  GLY E CA  1 
ATOM 5196 C C   . GLY D 4 54  ? 113.773 84.490  91.657  1.00 57.41  ? 54  GLY E C   1 
ATOM 5197 O O   . GLY D 4 54  ? 113.988 84.720  92.854  1.00 62.72  ? 54  GLY E O   1 
ATOM 5198 N N   . SER D 4 55  ? 113.840 83.262  91.138  1.00 55.55  ? 55  SER E N   1 
ATOM 5199 C CA  . SER D 4 55  ? 114.306 82.085  91.871  1.00 53.43  ? 55  SER E CA  1 
ATOM 5200 C C   . SER D 4 55  ? 113.411 81.738  93.057  1.00 50.11  ? 55  SER E C   1 
ATOM 5201 O O   . SER D 4 55  ? 113.822 80.993  93.952  1.00 53.52  ? 55  SER E O   1 
ATOM 5202 C CB  . SER D 4 55  ? 115.755 82.259  92.344  1.00 59.48  ? 55  SER E CB  1 
ATOM 5203 O OG  . SER D 4 55  ? 116.612 82.576  91.263  1.00 61.00  ? 55  SER E OG  1 
ATOM 5204 N N   . GLY D 4 56  ? 112.187 82.269  93.087  1.00 48.31  ? 56  GLY E N   1 
ATOM 5205 C CA  . GLY D 4 56  ? 111.309 82.027  94.218  1.00 55.10  ? 56  GLY E CA  1 
ATOM 5206 C C   . GLY D 4 56  ? 110.625 80.678  94.184  1.00 55.06  ? 56  GLY E C   1 
ATOM 5207 O O   . GLY D 4 56  ? 110.294 80.124  95.237  1.00 53.74  ? 56  GLY E O   1 
ATOM 5208 N N   . THR D 4 57  ? 110.398 80.134  92.991  1.00 47.86  ? 57  THR E N   1 
ATOM 5209 C CA  . THR D 4 57  ? 109.679 78.880  92.808  1.00 45.29  ? 57  THR E CA  1 
ATOM 5210 C C   . THR D 4 57  ? 110.566 77.894  92.064  1.00 40.88  ? 57  THR E C   1 
ATOM 5211 O O   . THR D 4 57  ? 111.165 78.242  91.041  1.00 51.41  ? 57  THR E O   1 
ATOM 5212 C CB  . THR D 4 57  ? 108.372 79.100  92.040  1.00 43.98  ? 57  THR E CB  1 
ATOM 5213 O OG1 . THR D 4 57  ? 107.585 80.095  92.708  1.00 42.61  ? 57  THR E OG1 1 
ATOM 5214 C CG2 . THR D 4 57  ? 107.579 77.806  91.952  1.00 41.62  ? 57  THR E CG2 1 
ATOM 5215 N N   . ILE D 4 58  ? 110.650 76.669  92.578  1.00 34.59  ? 58  ILE E N   1 
ATOM 5216 C CA  . ILE D 4 58  ? 111.454 75.608  91.984  1.00 34.53  ? 58  ILE E CA  1 
ATOM 5217 C C   . ILE D 4 58  ? 110.617 74.337  91.949  1.00 33.52  ? 58  ILE E C   1 
ATOM 5218 O O   . ILE D 4 58  ? 110.024 73.952  92.962  1.00 48.67  ? 58  ILE E O   1 
ATOM 5219 C CB  . ILE D 4 58  ? 112.762 75.372  92.764  1.00 43.49  ? 58  ILE E CB  1 
ATOM 5220 C CG1 . ILE D 4 58  ? 113.640 76.626  92.750  1.00 45.57  ? 58  ILE E CG1 1 
ATOM 5221 C CG2 . ILE D 4 58  ? 113.519 74.192  92.191  1.00 38.33  ? 58  ILE E CG2 1 
ATOM 5222 C CD1 . ILE D 4 58  ? 114.929 76.474  93.526  1.00 44.36  ? 58  ILE E CD1 1 
ATOM 5223 N N   . TYR D 4 59  ? 110.582 73.684  90.788  1.00 35.56  ? 59  TYR E N   1 
ATOM 5224 C CA  . TYR D 4 59  ? 109.851 72.439  90.599  1.00 36.01  ? 59  TYR E CA  1 
ATOM 5225 C C   . TYR D 4 59  ? 110.768 71.377  90.012  1.00 43.02  ? 59  TYR E C   1 
ATOM 5226 O O   . TYR D 4 59  ? 111.704 71.680  89.269  1.00 59.67  ? 59  TYR E O   1 
ATOM 5227 C CB  . TYR D 4 59  ? 108.635 72.626  89.681  1.00 49.43  ? 59  TYR E CB  1 
ATOM 5228 C CG  . TYR D 4 59  ? 107.542 73.487  90.266  1.00 44.92  ? 59  TYR E CG  1 
ATOM 5229 C CD1 . TYR D 4 59  ? 107.270 73.468  91.626  1.00 48.98  ? 59  TYR E CD1 1 
ATOM 5230 C CD2 . TYR D 4 59  ? 106.774 74.311  89.458  1.00 46.13  ? 59  TYR E CD2 1 
ATOM 5231 C CE1 . TYR D 4 59  ? 106.268 74.250  92.164  1.00 49.52  ? 59  TYR E CE1 1 
ATOM 5232 C CE2 . TYR D 4 59  ? 105.770 75.096  89.988  1.00 46.66  ? 59  TYR E CE2 1 
ATOM 5233 C CZ  . TYR D 4 59  ? 105.521 75.062  91.340  1.00 47.96  ? 59  TYR E CZ  1 
ATOM 5234 O OH  . TYR D 4 59  ? 104.521 75.846  91.868  1.00 57.28  ? 59  TYR E OH  1 
ATOM 5235 N N   . TYR D 4 60  ? 110.487 70.123  90.361  1.00 54.42  ? 60  TYR E N   1 
ATOM 5236 C CA  . TYR D 4 60  ? 111.236 68.981  89.865  1.00 63.79  ? 60  TYR E CA  1 
ATOM 5237 C C   . TYR D 4 60  ? 110.268 67.919  89.365  1.00 68.82  ? 60  TYR E C   1 
ATOM 5238 O O   . TYR D 4 60  ? 109.130 67.825  89.832  1.00 71.71  ? 60  TYR E O   1 
ATOM 5239 C CB  . TYR D 4 60  ? 112.144 68.384  90.950  1.00 69.74  ? 60  TYR E CB  1 
ATOM 5240 C CG  . TYR D 4 60  ? 113.265 69.301  91.377  1.00 62.82  ? 60  TYR E CG  1 
ATOM 5241 C CD1 . TYR D 4 60  ? 114.404 69.447  90.599  1.00 58.48  ? 60  TYR E CD1 1 
ATOM 5242 C CD2 . TYR D 4 60  ? 113.187 70.015  92.563  1.00 64.01  ? 60  TYR E CD2 1 
ATOM 5243 C CE1 . TYR D 4 60  ? 115.430 70.285  90.987  1.00 62.43  ? 60  TYR E CE1 1 
ATOM 5244 C CE2 . TYR D 4 60  ? 114.209 70.852  92.960  1.00 64.81  ? 60  TYR E CE2 1 
ATOM 5245 C CZ  . TYR D 4 60  ? 115.328 70.984  92.170  1.00 65.25  ? 60  TYR E CZ  1 
ATOM 5246 O OH  . TYR D 4 60  ? 116.347 71.820  92.562  1.00 70.62  ? 60  TYR E OH  1 
ATOM 5247 N N   . ALA D 4 61  ? 110.733 67.118  88.410  1.00 85.07  ? 61  ALA E N   1 
ATOM 5248 C CA  . ALA D 4 61  ? 109.987 65.935  88.011  1.00 86.65  ? 61  ALA E CA  1 
ATOM 5249 C C   . ALA D 4 61  ? 110.096 64.856  89.081  1.00 89.43  ? 61  ALA E C   1 
ATOM 5250 O O   . ALA D 4 61  ? 111.097 64.758  89.796  1.00 90.09  ? 61  ALA E O   1 
ATOM 5251 C CB  . ALA D 4 61  ? 110.501 65.402  86.673  1.00 86.23  ? 61  ALA E CB  1 
ATOM 5252 N N   . ASP D 4 62  ? 109.046 64.038  89.186  1.00 106.47 ? 62  ASP E N   1 
ATOM 5253 C CA  . ASP D 4 62  ? 109.016 63.009  90.222  1.00 107.87 ? 62  ASP E CA  1 
ATOM 5254 C C   . ASP D 4 62  ? 110.121 61.982  90.017  1.00 107.61 ? 62  ASP E C   1 
ATOM 5255 O O   . ASP D 4 62  ? 110.697 61.476  90.988  1.00 108.64 ? 62  ASP E O   1 
ATOM 5256 C CB  . ASP D 4 62  ? 107.649 62.326  90.242  1.00 109.24 ? 62  ASP E CB  1 
ATOM 5257 C CG  . ASP D 4 62  ? 106.514 63.303  90.463  1.00 112.03 ? 62  ASP E CG  1 
ATOM 5258 O OD1 . ASP D 4 62  ? 106.785 64.517  90.577  1.00 112.74 ? 62  ASP E OD1 1 
ATOM 5259 O OD2 . ASP D 4 62  ? 105.349 62.856  90.526  1.00 110.71 ? 62  ASP E OD2 1 
ATOM 5260 N N   . THR D 4 63  ? 110.435 61.661  88.760  1.00 101.24 ? 63  THR E N   1 
ATOM 5261 C CA  . THR D 4 63  ? 111.456 60.659  88.482  1.00 101.15 ? 63  THR E CA  1 
ATOM 5262 C C   . THR D 4 63  ? 112.854 61.149  88.831  1.00 100.41 ? 63  THR E C   1 
ATOM 5263 O O   . THR D 4 63  ? 113.777 60.334  88.933  1.00 103.23 ? 63  THR E O   1 
ATOM 5264 C CB  . THR D 4 63  ? 111.405 60.243  87.010  1.00 104.27 ? 63  THR E CB  1 
ATOM 5265 O OG1 . THR D 4 63  ? 112.435 59.283  86.746  1.00 105.75 ? 63  THR E OG1 1 
ATOM 5266 C CG2 . THR D 4 63  ? 111.600 61.452  86.105  1.00 102.71 ? 63  THR E CG2 1 
ATOM 5267 N N   . VAL D 4 64  ? 113.029 62.455  89.016  1.00 94.98  ? 64  VAL E N   1 
ATOM 5268 C CA  . VAL D 4 64  ? 114.330 63.029  89.340  1.00 96.53  ? 64  VAL E CA  1 
ATOM 5269 C C   . VAL D 4 64  ? 114.325 63.823  90.637  1.00 98.68  ? 64  VAL E C   1 
ATOM 5270 O O   . VAL D 4 64  ? 115.396 64.283  91.063  1.00 98.48  ? 64  VAL E O   1 
ATOM 5271 C CB  . VAL D 4 64  ? 114.859 63.912  88.190  1.00 99.26  ? 64  VAL E CB  1 
ATOM 5272 C CG1 . VAL D 4 64  ? 115.007 63.093  86.916  1.00 100.81 ? 64  VAL E CG1 1 
ATOM 5273 C CG2 . VAL D 4 64  ? 113.940 65.102  87.968  1.00 95.25  ? 64  VAL E CG2 1 
ATOM 5274 N N   . LYS D 4 65  ? 113.170 64.015  91.273  1.00 95.93  ? 65  LYS E N   1 
ATOM 5275 C CA  . LYS D 4 65  ? 113.103 64.839  92.474  1.00 92.62  ? 65  LYS E CA  1 
ATOM 5276 C C   . LYS D 4 65  ? 113.916 64.208  93.596  1.00 92.34  ? 65  LYS E C   1 
ATOM 5277 O O   . LYS D 4 65  ? 113.826 63.002  93.846  1.00 93.86  ? 65  LYS E O   1 
ATOM 5278 C CB  . LYS D 4 65  ? 111.650 65.023  92.910  1.00 87.95  ? 65  LYS E CB  1 
ATOM 5279 C CG  . LYS D 4 65  ? 111.463 66.006  94.054  1.00 88.63  ? 65  LYS E CG  1 
ATOM 5280 C CD  . LYS D 4 65  ? 109.990 66.217  94.359  1.00 91.77  ? 65  LYS E CD  1 
ATOM 5281 C CE  . LYS D 4 65  ? 109.795 67.238  95.467  1.00 92.39  ? 65  LYS E CE  1 
ATOM 5282 N NZ  . LYS D 4 65  ? 108.353 67.472  95.754  1.00 91.34  ? 65  LYS E NZ  1 
ATOM 5283 N N   . GLY D 4 66  ? 114.713 65.032  94.275  1.00 96.28  ? 66  GLY E N   1 
ATOM 5284 C CA  . GLY D 4 66  ? 115.617 64.564  95.298  1.00 97.82  ? 66  GLY E CA  1 
ATOM 5285 C C   . GLY D 4 66  ? 117.015 64.255  94.809  1.00 98.57  ? 66  GLY E C   1 
ATOM 5286 O O   . GLY D 4 66  ? 117.953 64.257  95.614  1.00 102.30 ? 66  GLY E O   1 
ATOM 5287 N N   . ARG D 4 67  ? 117.180 63.992  93.514  1.00 99.99  ? 67  ARG E N   1 
ATOM 5288 C CA  . ARG D 4 67  ? 118.483 63.724  92.922  1.00 100.68 ? 67  ARG E CA  1 
ATOM 5289 C C   . ARG D 4 67  ? 119.015 64.874  92.082  1.00 100.92 ? 67  ARG E C   1 
ATOM 5290 O O   . ARG D 4 67  ? 120.232 65.056  92.011  1.00 102.84 ? 67  ARG E O   1 
ATOM 5291 C CB  . ARG D 4 67  ? 118.418 62.461  92.054  1.00 99.21  ? 67  ARG E CB  1 
ATOM 5292 C CG  . ARG D 4 67  ? 117.851 61.252  92.782  1.00 100.77 ? 67  ARG E CG  1 
ATOM 5293 C CD  . ARG D 4 67  ? 117.839 60.008  91.906  1.00 102.49 ? 67  ARG E CD  1 
ATOM 5294 N NE  . ARG D 4 67  ? 117.001 60.172  90.723  1.00 102.89 ? 67  ARG E NE  1 
ATOM 5295 C CZ  . ARG D 4 67  ? 117.465 60.405  89.503  1.00 101.35 ? 67  ARG E CZ  1 
ATOM 5296 N NH1 . ARG D 4 67  ? 118.762 60.507  89.265  1.00 102.66 ? 67  ARG E NH1 1 
ATOM 5297 N NH2 . ARG D 4 67  ? 116.606 60.541  88.497  1.00 98.65  ? 67  ARG E NH2 1 
ATOM 5298 N N   . PHE D 4 68  ? 118.139 65.644  91.443  1.00 97.70  ? 68  PHE E N   1 
ATOM 5299 C CA  . PHE D 4 68  ? 118.540 66.763  90.602  1.00 98.64  ? 68  PHE E CA  1 
ATOM 5300 C C   . PHE D 4 68  ? 118.327 68.075  91.347  1.00 99.46  ? 68  PHE E C   1 
ATOM 5301 O O   . PHE D 4 68  ? 117.363 68.220  92.105  1.00 98.35  ? 68  PHE E O   1 
ATOM 5302 C CB  . PHE D 4 68  ? 117.756 66.782  89.287  1.00 98.57  ? 68  PHE E CB  1 
ATOM 5303 C CG  . PHE D 4 68  ? 118.166 65.710  88.310  1.00 97.79  ? 68  PHE E CG  1 
ATOM 5304 C CD1 . PHE D 4 68  ? 119.066 64.721  88.669  1.00 100.50 ? 68  PHE E CD1 1 
ATOM 5305 C CD2 . PHE D 4 68  ? 117.658 65.707  87.022  1.00 98.04  ? 68  PHE E CD2 1 
ATOM 5306 C CE1 . PHE D 4 68  ? 119.436 63.740  87.768  1.00 102.64 ? 68  PHE E CE1 1 
ATOM 5307 C CE2 . PHE D 4 68  ? 118.028 64.733  86.116  1.00 98.25  ? 68  PHE E CE2 1 
ATOM 5308 C CZ  . PHE D 4 68  ? 118.918 63.749  86.490  1.00 98.04  ? 68  PHE E CZ  1 
ATOM 5309 N N   . THR D 4 69  ? 119.241 69.023  91.142  1.00 93.41  ? 69  THR E N   1 
ATOM 5310 C CA  . THR D 4 69  ? 119.109 70.367  91.691  1.00 90.78  ? 69  THR E CA  1 
ATOM 5311 C C   . THR D 4 69  ? 119.306 71.385  90.578  1.00 91.45  ? 69  THR E C   1 
ATOM 5312 O O   . THR D 4 69  ? 120.316 71.346  89.868  1.00 91.83  ? 69  THR E O   1 
ATOM 5313 C CB  . THR D 4 69  ? 120.121 70.614  92.815  1.00 90.71  ? 69  THR E CB  1 
ATOM 5314 O OG1 . THR D 4 69  ? 119.927 69.648  93.857  1.00 92.04  ? 69  THR E OG1 1 
ATOM 5315 C CG2 . THR D 4 69  ? 119.946 72.010  93.391  1.00 89.98  ? 69  THR E CG2 1 
ATOM 5316 N N   . ILE D 4 70  ? 118.341 72.291  90.428  1.00 76.76  ? 70  ILE E N   1 
ATOM 5317 C CA  . ILE D 4 70  ? 118.370 73.333  89.406  1.00 73.92  ? 70  ILE E CA  1 
ATOM 5318 C C   . ILE D 4 70  ? 118.632 74.673  90.081  1.00 75.87  ? 70  ILE E C   1 
ATOM 5319 O O   . ILE D 4 70  ? 118.035 74.981  91.120  1.00 82.20  ? 70  ILE E O   1 
ATOM 5320 C CB  . ILE D 4 70  ? 117.063 73.360  88.591  1.00 71.22  ? 70  ILE E CB  1 
ATOM 5321 C CG1 . ILE D 4 70  ? 117.086 74.497  87.566  1.00 75.67  ? 70  ILE E CG1 1 
ATOM 5322 C CG2 . ILE D 4 70  ? 115.853 73.474  89.501  1.00 69.43  ? 70  ILE E CG2 1 
ATOM 5323 C CD1 . ILE D 4 70  ? 115.856 74.542  86.684  1.00 73.52  ? 70  ILE E CD1 1 
ATOM 5324 N N   . SER D 4 71  ? 119.538 75.459  89.503  1.00 77.44  ? 71  SER E N   1 
ATOM 5325 C CA  . SER D 4 71  ? 119.899 76.756  90.057  1.00 80.03  ? 71  SER E CA  1 
ATOM 5326 C C   . SER D 4 71  ? 120.298 77.683  88.918  1.00 80.33  ? 71  SER E C   1 
ATOM 5327 O O   . SER D 4 71  ? 120.583 77.240  87.803  1.00 80.04  ? 71  SER E O   1 
ATOM 5328 C CB  . SER D 4 71  ? 121.032 76.638  91.084  1.00 80.94  ? 71  SER E CB  1 
ATOM 5329 O OG  . SER D 4 71  ? 122.200 76.088  90.498  1.00 82.08  ? 71  SER E OG  1 
ATOM 5330 N N   . ARG D 4 72  ? 120.321 78.982  89.214  1.00 67.13  ? 72  ARG E N   1 
ATOM 5331 C CA  . ARG D 4 72  ? 120.670 79.989  88.223  1.00 67.58  ? 72  ARG E CA  1 
ATOM 5332 C C   . ARG D 4 72  ? 121.610 81.008  88.850  1.00 68.86  ? 72  ARG E C   1 
ATOM 5333 O O   . ARG D 4 72  ? 121.594 81.228  90.064  1.00 69.94  ? 72  ARG E O   1 
ATOM 5334 C CB  . ARG D 4 72  ? 119.424 80.696  87.663  1.00 68.75  ? 72  ARG E CB  1 
ATOM 5335 C CG  . ARG D 4 72  ? 118.676 81.547  88.677  1.00 64.48  ? 72  ARG E CG  1 
ATOM 5336 C CD  . ARG D 4 72  ? 117.277 81.901  88.189  1.00 61.07  ? 72  ARG E CD  1 
ATOM 5337 N NE  . ARG D 4 72  ? 117.290 82.574  86.896  1.00 61.90  ? 72  ARG E NE  1 
ATOM 5338 C CZ  . ARG D 4 72  ? 116.204 82.992  86.260  1.00 61.15  ? 72  ARG E CZ  1 
ATOM 5339 N NH1 . ARG D 4 72  ? 114.996 82.828  86.773  1.00 57.31  ? 72  ARG E NH1 1 
ATOM 5340 N NH2 . ARG D 4 72  ? 116.334 83.593  85.080  1.00 66.84  ? 72  ARG E NH2 1 
ATOM 5341 N N   . ASP D 4 73  ? 122.434 81.624  88.007  1.00 98.02  ? 73  ASP E N   1 
ATOM 5342 C CA  . ASP D 4 73  ? 123.333 82.707  88.404  1.00 101.46 ? 73  ASP E CA  1 
ATOM 5343 C C   . ASP D 4 73  ? 123.028 83.927  87.538  1.00 100.60 ? 73  ASP E C   1 
ATOM 5344 O O   . ASP D 4 73  ? 123.540 84.052  86.422  1.00 98.68  ? 73  ASP E O   1 
ATOM 5345 C CB  . ASP D 4 73  ? 124.792 82.273  88.279  1.00 102.63 ? 73  ASP E CB  1 
ATOM 5346 C CG  . ASP D 4 73  ? 125.743 83.221  88.980  1.00 103.09 ? 73  ASP E CG  1 
ATOM 5347 O OD1 . ASP D 4 73  ? 125.264 84.174  89.628  1.00 103.02 ? 73  ASP E OD1 1 
ATOM 5348 O OD2 . ASP D 4 73  ? 126.970 83.010  88.889  1.00 103.43 ? 73  ASP E OD2 1 
ATOM 5349 N N   . ASP D 4 74  ? 122.179 84.818  88.053  1.00 94.28  ? 74  ASP E N   1 
ATOM 5350 C CA  . ASP D 4 74  ? 121.750 85.977  87.272  1.00 94.03  ? 74  ASP E CA  1 
ATOM 5351 C C   . ASP D 4 74  ? 122.900 86.892  86.862  1.00 92.14  ? 74  ASP E C   1 
ATOM 5352 O O   . ASP D 4 74  ? 122.932 87.311  85.692  1.00 92.11  ? 74  ASP E O   1 
ATOM 5353 C CB  . ASP D 4 74  ? 120.677 86.750  88.047  1.00 92.05  ? 74  ASP E CB  1 
ATOM 5354 C CG  . ASP D 4 74  ? 119.443 85.916  88.322  1.00 92.73  ? 74  ASP E CG  1 
ATOM 5355 O OD1 . ASP D 4 74  ? 119.438 84.720  87.960  1.00 93.92  ? 74  ASP E OD1 1 
ATOM 5356 O OD2 . ASP D 4 74  ? 118.476 86.456  88.899  1.00 92.46  ? 74  ASP E OD2 1 
ATOM 5357 N N   . PRO D 4 75  ? 123.848 87.259  87.739  1.00 99.43  ? 75  PRO E N   1 
ATOM 5358 C CA  . PRO D 4 75  ? 124.959 88.108  87.270  1.00 100.18 ? 75  PRO E CA  1 
ATOM 5359 C C   . PRO D 4 75  ? 125.775 87.489  86.148  1.00 99.27  ? 75  PRO E C   1 
ATOM 5360 O O   . PRO D 4 75  ? 126.242 88.213  85.259  1.00 101.11 ? 75  PRO E O   1 
ATOM 5361 C CB  . PRO D 4 75  ? 125.800 88.312  88.538  1.00 100.96 ? 75  PRO E CB  1 
ATOM 5362 C CG  . PRO D 4 75  ? 124.839 88.144  89.652  1.00 101.97 ? 75  PRO E CG  1 
ATOM 5363 C CD  . PRO D 4 75  ? 123.901 87.068  89.201  1.00 102.04 ? 75  PRO E CD  1 
ATOM 5364 N N   . LYS D 4 76  ? 125.966 86.172  86.160  1.00 92.63  ? 76  LYS E N   1 
ATOM 5365 C CA  . LYS D 4 76  ? 126.715 85.497  85.108  1.00 97.02  ? 76  LYS E CA  1 
ATOM 5366 C C   . LYS D 4 76  ? 125.833 85.005  83.969  1.00 99.14  ? 76  LYS E C   1 
ATOM 5367 O O   . LYS D 4 76  ? 126.363 84.496  82.975  1.00 96.21  ? 76  LYS E O   1 
ATOM 5368 C CB  . LYS D 4 76  ? 127.506 84.321  85.692  1.00 96.82  ? 76  LYS E CB  1 
ATOM 5369 C CG  . LYS D 4 76  ? 128.654 84.739  86.597  1.00 97.97  ? 76  LYS E CG  1 
ATOM 5370 C CD  . LYS D 4 76  ? 129.518 83.549  86.978  1.00 97.35  ? 76  LYS E CD  1 
ATOM 5371 C CE  . LYS D 4 76  ? 130.684 83.974  87.856  1.00 96.91  ? 76  LYS E CE  1 
ATOM 5372 N NZ  . LYS D 4 76  ? 131.545 82.819  88.231  1.00 98.67  ? 76  LYS E NZ  1 
ATOM 5373 N N   . ASN D 4 77  ? 124.511 85.146  84.089  1.00 99.88  ? 77  ASN E N   1 
ATOM 5374 C CA  . ASN D 4 77  ? 123.564 84.690  83.068  1.00 96.74  ? 77  ASN E CA  1 
ATOM 5375 C C   . ASN D 4 77  ? 123.760 83.209  82.750  1.00 94.80  ? 77  ASN E C   1 
ATOM 5376 O O   . ASN D 4 77  ? 123.761 82.800  81.588  1.00 94.79  ? 77  ASN E O   1 
ATOM 5377 C CB  . ASN D 4 77  ? 123.672 85.536  81.797  1.00 95.34  ? 77  ASN E CB  1 
ATOM 5378 C CG  . ASN D 4 77  ? 123.316 86.990  82.032  1.00 98.41  ? 77  ASN E CG  1 
ATOM 5379 O OD1 . ASN D 4 77  ? 122.450 87.305  82.848  1.00 98.07  ? 77  ASN E OD1 1 
ATOM 5380 N ND2 . ASN D 4 77  ? 123.986 87.887  81.317  1.00 98.09  ? 77  ASN E ND2 1 
ATOM 5381 N N   . THR D 4 78  ? 123.922 82.397  83.791  1.00 95.55  ? 78  THR E N   1 
ATOM 5382 C CA  . THR D 4 78  ? 124.142 80.964  83.644  1.00 97.08  ? 78  THR E CA  1 
ATOM 5383 C C   . THR D 4 78  ? 123.055 80.202  84.386  1.00 94.87  ? 78  THR E C   1 
ATOM 5384 O O   . THR D 4 78  ? 122.723 80.538  85.527  1.00 94.21  ? 78  THR E O   1 
ATOM 5385 C CB  . THR D 4 78  ? 125.523 80.559  84.168  1.00 100.60 ? 78  THR E CB  1 
ATOM 5386 O OG1 . THR D 4 78  ? 126.519 81.426  83.613  1.00 102.10 ? 78  THR E OG1 1 
ATOM 5387 C CG2 . THR D 4 78  ? 125.839 79.126  83.768  1.00 94.51  ? 78  THR E CG2 1 
ATOM 5388 N N   . LEU D 4 79  ? 122.507 79.180  83.736  1.00 91.55  ? 79  LEU E N   1 
ATOM 5389 C CA  . LEU D 4 79  ? 121.547 78.272  84.346  1.00 91.52  ? 79  LEU E CA  1 
ATOM 5390 C C   . LEU D 4 79  ? 122.214 76.931  84.612  1.00 93.04  ? 79  LEU E C   1 
ATOM 5391 O O   . LEU D 4 79  ? 122.946 76.412  83.763  1.00 93.94  ? 79  LEU E O   1 
ATOM 5392 C CB  . LEU D 4 79  ? 120.328 78.074  83.444  1.00 90.15  ? 79  LEU E CB  1 
ATOM 5393 C CG  . LEU D 4 79  ? 119.237 77.156  83.997  1.00 89.65  ? 79  LEU E CG  1 
ATOM 5394 C CD1 . LEU D 4 79  ? 118.442 77.853  85.093  1.00 88.18  ? 79  LEU E CD1 1 
ATOM 5395 C CD2 . LEU D 4 79  ? 118.331 76.660  82.883  1.00 87.85  ? 79  LEU E CD2 1 
ATOM 5396 N N   . PHE D 4 80  ? 121.960 76.371  85.792  1.00 92.55  ? 80  PHE E N   1 
ATOM 5397 C CA  . PHE D 4 80  ? 122.611 75.146  86.227  1.00 92.02  ? 80  PHE E CA  1 
ATOM 5398 C C   . PHE D 4 80  ? 121.589 74.044  86.471  1.00 90.48  ? 80  PHE E C   1 
ATOM 5399 O O   . PHE D 4 80  ? 120.426 74.306  86.791  1.00 92.74  ? 80  PHE E O   1 
ATOM 5400 C CB  . PHE D 4 80  ? 123.423 75.372  87.507  1.00 90.55  ? 80  PHE E CB  1 
ATOM 5401 C CG  . PHE D 4 80  ? 124.491 76.418  87.373  1.00 91.02  ? 80  PHE E CG  1 
ATOM 5402 C CD1 . PHE D 4 80  ? 125.755 76.079  86.920  1.00 91.59  ? 80  PHE E CD1 1 
ATOM 5403 C CD2 . PHE D 4 80  ? 124.237 77.737  87.711  1.00 89.57  ? 80  PHE E CD2 1 
ATOM 5404 C CE1 . PHE D 4 80  ? 126.743 77.035  86.799  1.00 93.24  ? 80  PHE E CE1 1 
ATOM 5405 C CE2 . PHE D 4 80  ? 125.222 78.698  87.593  1.00 91.89  ? 80  PHE E CE2 1 
ATOM 5406 C CZ  . PHE D 4 80  ? 126.477 78.346  87.137  1.00 93.94  ? 80  PHE E CZ  1 
ATOM 5407 N N   . LEU D 4 81  ? 122.045 72.803  86.310  1.00 91.46  ? 81  LEU E N   1 
ATOM 5408 C CA  . LEU D 4 81  ? 121.276 71.614  86.676  1.00 91.51  ? 81  LEU E CA  1 
ATOM 5409 C C   . LEU D 4 81  ? 122.265 70.630  87.292  1.00 91.86  ? 81  LEU E C   1 
ATOM 5410 O O   . LEU D 4 81  ? 123.037 69.989  86.573  1.00 91.86  ? 81  LEU E O   1 
ATOM 5411 C CB  . LEU D 4 81  ? 120.560 71.011  85.473  1.00 90.55  ? 81  LEU E CB  1 
ATOM 5412 C CG  . LEU D 4 81  ? 119.547 69.905  85.781  1.00 92.08  ? 81  LEU E CG  1 
ATOM 5413 C CD1 . LEU D 4 81  ? 118.434 70.431  86.671  1.00 88.52  ? 81  LEU E CD1 1 
ATOM 5414 C CD2 . LEU D 4 81  ? 118.980 69.319  84.497  1.00 93.47  ? 81  LEU E CD2 1 
ATOM 5415 N N   . GLN D 4 82  ? 122.239 70.512  88.617  1.00 101.17 ? 82  GLN E N   1 
ATOM 5416 C CA  . GLN D 4 82  ? 123.111 69.586  89.328  1.00 104.06 ? 82  GLN E CA  1 
ATOM 5417 C C   . GLN D 4 82  ? 122.445 68.220  89.418  1.00 105.23 ? 82  GLN E C   1 
ATOM 5418 O O   . GLN D 4 82  ? 121.354 68.090  89.984  1.00 105.25 ? 82  GLN E O   1 
ATOM 5419 C CB  . GLN D 4 82  ? 123.437 70.114  90.724  1.00 103.80 ? 82  GLN E CB  1 
ATOM 5420 C CG  . GLN D 4 82  ? 124.109 69.093  91.629  1.00 106.39 ? 82  GLN E CG  1 
ATOM 5421 C CD  . GLN D 4 82  ? 125.436 68.608  91.078  1.00 107.20 ? 82  GLN E CD  1 
ATOM 5422 O OE1 . GLN D 4 82  ? 126.233 69.394  90.569  1.00 105.74 ? 82  GLN E OE1 1 
ATOM 5423 N NE2 . GLN D 4 82  ? 125.678 67.306  91.176  1.00 106.28 ? 82  GLN E NE2 1 
ATOM 5424 N N   . MET D 4 83  ? 123.104 67.206  88.863  1.00 114.31 ? 83  MET E N   1 
ATOM 5425 C CA  . MET D 4 83  ? 122.588 65.847  88.822  1.00 113.80 ? 83  MET E CA  1 
ATOM 5426 C C   . MET D 4 83  ? 123.487 64.940  89.650  1.00 116.52 ? 83  MET E C   1 
ATOM 5427 O O   . MET D 4 83  ? 124.714 65.069  89.615  1.00 116.80 ? 83  MET E O   1 
ATOM 5428 C CB  . MET D 4 83  ? 122.501 65.332  87.384  1.00 115.14 ? 83  MET E CB  1 
ATOM 5429 C CG  . MET D 4 83  ? 121.661 66.202  86.464  1.00 117.12 ? 83  MET E CG  1 
ATOM 5430 S SD  . MET D 4 83  ? 121.670 65.600  84.767  1.00 124.29 ? 83  MET E SD  1 
ATOM 5431 C CE  . MET D 4 83  ? 123.429 65.589  84.434  1.00 118.39 ? 83  MET E CE  1 
ATOM 5432 N N   . THR D 4 84  ? 122.871 64.023  90.394  1.00 121.39 ? 84  THR E N   1 
ATOM 5433 C CA  . THR D 4 84  ? 123.601 63.081  91.228  1.00 121.73 ? 84  THR E CA  1 
ATOM 5434 C C   . THR D 4 84  ? 122.996 61.693  91.080  1.00 120.22 ? 84  THR E C   1 
ATOM 5435 O O   . THR D 4 84  ? 121.821 61.538  90.736  1.00 117.04 ? 84  THR E O   1 
ATOM 5436 C CB  . THR D 4 84  ? 123.586 63.494  92.707  1.00 120.49 ? 84  THR E CB  1 
ATOM 5437 O OG1 . THR D 4 84  ? 122.237 63.740  93.123  1.00 120.68 ? 84  THR E OG1 1 
ATOM 5438 C CG2 . THR D 4 84  ? 124.422 64.747  92.929  1.00 119.97 ? 84  THR E CG2 1 
ATOM 5439 N N   . SER D 4 85  ? 123.824 60.680  91.350  1.00 131.07 ? 85  SER E N   1 
ATOM 5440 C CA  . SER D 4 85  ? 123.411 59.276  91.305  1.00 131.35 ? 85  SER E CA  1 
ATOM 5441 C C   . SER D 4 85  ? 122.818 58.920  89.942  1.00 131.53 ? 85  SER E C   1 
ATOM 5442 O O   . SER D 4 85  ? 121.748 58.315  89.841  1.00 129.69 ? 85  SER E O   1 
ATOM 5443 C CB  . SER D 4 85  ? 122.428 58.957  92.434  1.00 130.56 ? 85  SER E CB  1 
ATOM 5444 O OG  . SER D 4 85  ? 123.018 59.188  93.702  1.00 129.86 ? 85  SER E OG  1 
ATOM 5445 N N   . LEU D 4 86  ? 123.525 59.313  88.885  1.00 137.85 ? 86  LEU E N   1 
ATOM 5446 C CA  . LEU D 4 86  ? 123.013 59.141  87.532  1.00 136.84 ? 86  LEU E CA  1 
ATOM 5447 C C   . LEU D 4 86  ? 122.841 57.665  87.198  1.00 137.03 ? 86  LEU E C   1 
ATOM 5448 O O   . LEU D 4 86  ? 123.723 56.844  87.464  1.00 137.24 ? 86  LEU E O   1 
ATOM 5449 C CB  . LEU D 4 86  ? 123.953 59.802  86.526  1.00 137.04 ? 86  LEU E CB  1 
ATOM 5450 C CG  . LEU D 4 86  ? 123.958 61.330  86.521  1.00 137.89 ? 86  LEU E CG  1 
ATOM 5451 C CD1 . LEU D 4 86  ? 124.970 61.852  85.519  1.00 138.19 ? 86  LEU E CD1 1 
ATOM 5452 C CD2 . LEU D 4 86  ? 122.569 61.859  86.209  1.00 137.09 ? 86  LEU E CD2 1 
ATOM 5453 N N   . ARG D 4 87  ? 121.698 57.337  86.609  1.00 141.25 ? 87  ARG E N   1 
ATOM 5454 C CA  . ARG D 4 87  ? 121.343 55.979  86.229  1.00 141.25 ? 87  ARG E CA  1 
ATOM 5455 C C   . ARG D 4 87  ? 121.337 55.859  84.711  1.00 142.35 ? 87  ARG E C   1 
ATOM 5456 O O   . ARG D 4 87  ? 121.416 56.852  83.984  1.00 143.67 ? 87  ARG E O   1 
ATOM 5457 C CB  . ARG D 4 87  ? 119.979 55.591  86.811  1.00 140.19 ? 87  ARG E CB  1 
ATOM 5458 C CG  . ARG D 4 87  ? 119.818 55.938  88.282  1.00 140.79 ? 87  ARG E CG  1 
ATOM 5459 C CD  . ARG D 4 87  ? 118.382 55.752  88.744  1.00 142.63 ? 87  ARG E CD  1 
ATOM 5460 N NE  . ARG D 4 87  ? 118.193 56.201  90.119  1.00 143.97 ? 87  ARG E NE  1 
ATOM 5461 C CZ  . ARG D 4 87  ? 117.024 56.228  90.744  1.00 141.47 ? 87  ARG E CZ  1 
ATOM 5462 N NH1 . ARG D 4 87  ? 115.910 55.838  90.145  1.00 139.65 ? 87  ARG E NH1 1 
ATOM 5463 N NH2 . ARG D 4 87  ? 116.971 56.658  92.002  1.00 140.04 ? 87  ARG E NH2 1 
ATOM 5464 N N   . SER D 4 88  ? 121.238 54.616  84.234  1.00 144.25 ? 88  SER E N   1 
ATOM 5465 C CA  . SER D 4 88  ? 121.142 54.391  82.796  1.00 143.45 ? 88  SER E CA  1 
ATOM 5466 C C   . SER D 4 88  ? 119.866 54.979  82.211  1.00 143.05 ? 88  SER E C   1 
ATOM 5467 O O   . SER D 4 88  ? 119.802 55.212  80.999  1.00 141.55 ? 88  SER E O   1 
ATOM 5468 C CB  . SER D 4 88  ? 121.214 52.894  82.492  1.00 142.31 ? 88  SER E CB  1 
ATOM 5469 O OG  . SER D 4 88  ? 120.149 52.197  83.115  1.00 141.65 ? 88  SER E OG  1 
ATOM 5470 N N   . GLU D 4 89  ? 118.851 55.225  83.042  1.00 139.94 ? 89  GLU E N   1 
ATOM 5471 C CA  . GLU D 4 89  ? 117.631 55.873  82.582  1.00 139.63 ? 89  GLU E CA  1 
ATOM 5472 C C   . GLU D 4 89  ? 117.825 57.361  82.317  1.00 139.52 ? 89  GLU E C   1 
ATOM 5473 O O   . GLU D 4 89  ? 116.961 57.980  81.687  1.00 140.33 ? 89  GLU E O   1 
ATOM 5474 C CB  . GLU D 4 89  ? 116.517 55.658  83.611  1.00 138.29 ? 89  GLU E CB  1 
ATOM 5475 C CG  . GLU D 4 89  ? 115.104 55.860  83.081  1.00 138.52 ? 89  GLU E CG  1 
ATOM 5476 C CD  . GLU D 4 89  ? 114.585 57.265  83.319  1.00 140.59 ? 89  GLU E CD  1 
ATOM 5477 O OE1 . GLU D 4 89  ? 115.264 58.038  84.028  1.00 142.42 ? 89  GLU E OE1 1 
ATOM 5478 O OE2 . GLU D 4 89  ? 113.501 57.597  82.796  1.00 137.92 ? 89  GLU E OE2 1 
ATOM 5479 N N   . ASP D 4 90  ? 118.942 57.940  82.752  1.00 136.35 ? 90  ASP E N   1 
ATOM 5480 C CA  . ASP D 4 90  ? 119.198 59.363  82.583  1.00 134.41 ? 90  ASP E CA  1 
ATOM 5481 C C   . ASP D 4 90  ? 119.954 59.685  81.301  1.00 133.49 ? 90  ASP E C   1 
ATOM 5482 O O   . ASP D 4 90  ? 120.244 60.860  81.050  1.00 133.93 ? 90  ASP E O   1 
ATOM 5483 C CB  . ASP D 4 90  ? 119.980 59.904  83.786  1.00 136.73 ? 90  ASP E CB  1 
ATOM 5484 C CG  . ASP D 4 90  ? 119.291 59.617  85.105  1.00 139.08 ? 90  ASP E CG  1 
ATOM 5485 O OD1 . ASP D 4 90  ? 118.230 58.959  85.092  1.00 140.07 ? 90  ASP E OD1 1 
ATOM 5486 O OD2 . ASP D 4 90  ? 119.809 60.050  86.156  1.00 138.05 ? 90  ASP E OD2 1 
ATOM 5487 N N   . THR D 4 91  ? 120.279 58.681  80.490  1.00 136.72 ? 91  THR E N   1 
ATOM 5488 C CA  . THR D 4 91  ? 120.975 58.912  79.228  1.00 139.28 ? 91  THR E CA  1 
ATOM 5489 C C   . THR D 4 91  ? 120.028 59.609  78.259  1.00 138.72 ? 91  THR E C   1 
ATOM 5490 O O   . THR D 4 91  ? 119.087 58.991  77.750  1.00 138.30 ? 91  THR E O   1 
ATOM 5491 C CB  . THR D 4 91  ? 121.474 57.591  78.649  1.00 139.47 ? 91  THR E CB  1 
ATOM 5492 O OG1 . THR D 4 91  ? 122.414 56.996  79.551  1.00 139.26 ? 91  THR E OG1 1 
ATOM 5493 C CG2 . THR D 4 91  ? 122.143 57.816  77.301  1.00 136.52 ? 91  THR E CG2 1 
ATOM 5494 N N   . ALA D 4 92  ? 120.274 60.891  77.998  1.00 124.21 ? 92  ALA E N   1 
ATOM 5495 C CA  . ALA D 4 92  ? 119.401 61.668  77.129  1.00 123.57 ? 92  ALA E CA  1 
ATOM 5496 C C   . ALA D 4 92  ? 120.116 62.947  76.716  1.00 123.56 ? 92  ALA E C   1 
ATOM 5497 O O   . ALA D 4 92  ? 121.165 63.303  77.258  1.00 122.06 ? 92  ALA E O   1 
ATOM 5498 C CB  . ALA D 4 92  ? 118.072 61.992  77.819  1.00 120.95 ? 92  ALA E CB  1 
ATOM 5499 N N   . MET D 4 93  ? 119.527 63.632  75.740  1.00 114.91 ? 93  MET E N   1 
ATOM 5500 C CA  . MET D 4 93  ? 119.932 64.982  75.373  1.00 112.62 ? 93  MET E CA  1 
ATOM 5501 C C   . MET D 4 93  ? 119.104 65.984  76.169  1.00 115.53 ? 93  MET E C   1 
ATOM 5502 O O   . MET D 4 93  ? 117.873 65.988  76.076  1.00 117.11 ? 93  MET E O   1 
ATOM 5503 C CB  . MET D 4 93  ? 119.753 65.210  73.872  1.00 110.19 ? 93  MET E CB  1 
ATOM 5504 C CG  . MET D 4 93  ? 120.102 66.615  73.410  1.00 112.90 ? 93  MET E CG  1 
ATOM 5505 S SD  . MET D 4 93  ? 121.773 66.736  72.748  1.00 123.01 ? 93  MET E SD  1 
ATOM 5506 C CE  . MET D 4 93  ? 121.604 65.778  71.244  1.00 115.39 ? 93  MET E CE  1 
ATOM 5507 N N   . TYR D 4 94  ? 119.778 66.837  76.935  1.00 105.34 ? 94  TYR E N   1 
ATOM 5508 C CA  . TYR D 4 94  ? 119.122 67.774  77.838  1.00 103.79 ? 94  TYR E CA  1 
ATOM 5509 C C   . TYR D 4 94  ? 119.072 69.148  77.180  1.00 101.05 ? 94  TYR E C   1 
ATOM 5510 O O   . TYR D 4 94  ? 120.115 69.704  76.820  1.00 98.26  ? 94  TYR E O   1 
ATOM 5511 C CB  . TYR D 4 94  ? 119.855 67.846  79.177  1.00 102.73 ? 94  TYR E CB  1 
ATOM 5512 C CG  . TYR D 4 94  ? 119.620 66.653  80.077  1.00 99.57  ? 94  TYR E CG  1 
ATOM 5513 C CD1 . TYR D 4 94  ? 120.321 65.470  79.891  1.00 99.86  ? 94  TYR E CD1 1 
ATOM 5514 C CD2 . TYR D 4 94  ? 118.705 66.714  81.120  1.00 97.80  ? 94  TYR E CD2 1 
ATOM 5515 C CE1 . TYR D 4 94  ? 120.113 64.378  80.712  1.00 101.58 ? 94  TYR E CE1 1 
ATOM 5516 C CE2 . TYR D 4 94  ? 118.490 65.627  81.946  1.00 99.28  ? 94  TYR E CE2 1 
ATOM 5517 C CZ  . TYR D 4 94  ? 119.197 64.462  81.737  1.00 102.27 ? 94  TYR E CZ  1 
ATOM 5518 O OH  . TYR D 4 94  ? 118.989 63.375  82.555  1.00 103.47 ? 94  TYR E OH  1 
ATOM 5519 N N   . TYR D 4 95  ? 117.868 69.694  77.037  1.00 88.08  ? 95  TYR E N   1 
ATOM 5520 C CA  . TYR D 4 95  ? 117.652 70.968  76.367  1.00 88.09  ? 95  TYR E CA  1 
ATOM 5521 C C   . TYR D 4 95  ? 117.361 72.060  77.386  1.00 88.08  ? 95  TYR E C   1 
ATOM 5522 O O   . TYR D 4 95  ? 116.664 71.830  78.380  1.00 88.66  ? 95  TYR E O   1 
ATOM 5523 C CB  . TYR D 4 95  ? 116.500 70.877  75.361  1.00 87.91  ? 95  TYR E CB  1 
ATOM 5524 C CG  . TYR D 4 95  ? 116.774 69.953  74.196  1.00 88.69  ? 95  TYR E CG  1 
ATOM 5525 C CD1 . TYR D 4 95  ? 117.436 70.412  73.066  1.00 89.66  ? 95  TYR E CD1 1 
ATOM 5526 C CD2 . TYR D 4 95  ? 116.371 68.625  74.225  1.00 87.36  ? 95  TYR E CD2 1 
ATOM 5527 C CE1 . TYR D 4 95  ? 117.692 69.576  71.998  1.00 91.20  ? 95  TYR E CE1 1 
ATOM 5528 C CE2 . TYR D 4 95  ? 116.622 67.780  73.159  1.00 89.48  ? 95  TYR E CE2 1 
ATOM 5529 C CZ  . TYR D 4 95  ? 117.283 68.261  72.049  1.00 91.69  ? 95  TYR E CZ  1 
ATOM 5530 O OH  . TYR D 4 95  ? 117.536 67.425  70.986  1.00 87.97  ? 95  TYR E OH  1 
ATOM 5531 N N   . CYS D 4 96  ? 117.903 73.247  77.131  1.00 73.71  ? 96  CYS E N   1 
ATOM 5532 C CA  . CYS D 4 96  ? 117.647 74.433  77.938  1.00 68.80  ? 96  CYS E CA  1 
ATOM 5533 C C   . CYS D 4 96  ? 116.554 75.260  77.271  1.00 65.84  ? 96  CYS E C   1 
ATOM 5534 O O   . CYS D 4 96  ? 116.693 75.658  76.110  1.00 76.50  ? 96  CYS E O   1 
ATOM 5535 C CB  . CYS D 4 96  ? 118.922 75.259  78.103  1.00 74.10  ? 96  CYS E CB  1 
ATOM 5536 S SG  . CYS D 4 96  ? 118.798 76.622  79.276  1.00 82.38  ? 96  CYS E SG  1 
ATOM 5537 N N   . VAL D 4 97  ? 115.471 75.512  78.002  1.00 31.98  ? 97  VAL E N   1 
ATOM 5538 C CA  . VAL D 4 97  ? 114.284 76.164  77.463  1.00 42.36  ? 97  VAL E CA  1 
ATOM 5539 C C   . VAL D 4 97  ? 113.990 77.405  78.291  1.00 44.69  ? 97  VAL E C   1 
ATOM 5540 O O   . VAL D 4 97  ? 113.921 77.334  79.524  1.00 55.59  ? 97  VAL E O   1 
ATOM 5541 C CB  . VAL D 4 97  ? 113.067 75.221  77.463  1.00 44.98  ? 97  VAL E CB  1 
ATOM 5542 C CG1 . VAL D 4 97  ? 111.947 75.804  76.619  1.00 50.21  ? 97  VAL E CG1 1 
ATOM 5543 C CG2 . VAL D 4 97  ? 113.465 73.839  76.972  1.00 51.06  ? 97  VAL E CG2 1 
ATOM 5544 N N   . ARG D 4 98  ? 113.823 78.537  77.615  1.00 46.72  ? 98  ARG E N   1 
ATOM 5545 C CA  . ARG D 4 98  ? 113.399 79.773  78.255  1.00 40.32  ? 98  ARG E CA  1 
ATOM 5546 C C   . ARG D 4 98  ? 111.885 79.924  78.175  1.00 39.88  ? 98  ARG E C   1 
ATOM 5547 O O   . ARG D 4 98  ? 111.241 79.452  77.234  1.00 50.14  ? 98  ARG E O   1 
ATOM 5548 C CB  . ARG D 4 98  ? 114.083 80.983  77.613  1.00 48.49  ? 98  ARG E CB  1 
ATOM 5549 C CG  . ARG D 4 98  ? 113.423 81.488  76.339  1.00 48.94  ? 98  ARG E CG  1 
ATOM 5550 C CD  . ARG D 4 98  ? 114.054 82.792  75.881  1.00 39.80  ? 98  ARG E CD  1 
ATOM 5551 N NE  . ARG D 4 98  ? 113.234 83.495  74.901  1.00 50.26  ? 98  ARG E NE  1 
ATOM 5552 C CZ  . ARG D 4 98  ? 113.549 84.666  74.366  1.00 52.48  ? 98  ARG E CZ  1 
ATOM 5553 N NH1 . ARG D 4 98  ? 114.669 85.294  74.686  1.00 49.54  ? 98  ARG E NH1 1 
ATOM 5554 N NH2 . ARG D 4 98  ? 112.721 85.221  73.486  1.00 49.37  ? 98  ARG E NH2 1 
ATOM 5555 N N   . SER D 4 99  ? 111.317 80.565  79.194  1.00 29.91  ? 99  SER E N   1 
ATOM 5556 C CA  . SER D 4 99  ? 109.878 80.818  79.229  1.00 29.61  ? 99  SER E CA  1 
ATOM 5557 C C   . SER D 4 99  ? 109.623 82.010  80.134  1.00 40.46  ? 99  SER E C   1 
ATOM 5558 O O   . SER D 4 99  ? 110.013 81.991  81.306  1.00 57.79  ? 99  SER E O   1 
ATOM 5559 C CB  . SER D 4 99  ? 109.114 79.594  79.730  1.00 52.32  ? 99  SER E CB  1 
ATOM 5560 O OG  . SER D 4 99  ? 109.293 79.428  81.125  1.00 58.34  ? 99  SER E OG  1 
ATOM 5561 N N   . ILE D 4 100 ? 108.967 83.037  79.603  1.00 45.80  ? 100 ILE E N   1 
ATOM 5562 C CA  . ILE D 4 100 ? 108.618 84.235  80.356  1.00 51.26  ? 100 ILE E CA  1 
ATOM 5563 C C   . ILE D 4 100 ? 107.108 84.248  80.543  1.00 40.89  ? 100 ILE E C   1 
ATOM 5564 O O   . ILE D 4 100 ? 106.361 83.816  79.657  1.00 49.17  ? 100 ILE E O   1 
ATOM 5565 C CB  . ILE D 4 100 ? 109.112 85.515  79.651  1.00 47.55  ? 100 ILE E CB  1 
ATOM 5566 C CG1 . ILE D 4 100 ? 108.881 86.745  80.532  1.00 39.84  ? 100 ILE E CG1 1 
ATOM 5567 C CG2 . ILE D 4 100 ? 108.442 85.685  78.294  1.00 54.63  ? 100 ILE E CG2 1 
ATOM 5568 C CD1 . ILE D 4 100 ? 109.495 88.010  79.983  1.00 35.28  ? 100 ILE E CD1 1 
ATOM 5569 N N   . TYR D 4 101 ? 106.655 84.725  81.701  1.00 22.98  ? 101 TYR E N   1 
ATOM 5570 C CA  . TYR D 4 101 ? 105.246 84.633  82.070  1.00 32.68  ? 101 TYR E CA  1 
ATOM 5571 C C   . TYR D 4 101 ? 104.707 86.016  82.398  1.00 41.01  ? 101 TYR E C   1 
ATOM 5572 O O   . TYR D 4 101 ? 105.025 86.584  83.448  1.00 44.46  ? 101 TYR E O   1 
ATOM 5573 C CB  . TYR D 4 101 ? 105.043 83.688  83.254  1.00 48.19  ? 101 TYR E CB  1 
ATOM 5574 C CG  . TYR D 4 101 ? 105.547 82.286  83.018  1.00 47.25  ? 101 TYR E CG  1 
ATOM 5575 C CD1 . TYR D 4 101 ? 104.747 81.339  82.395  1.00 39.20  ? 101 TYR E CD1 1 
ATOM 5576 C CD2 . TYR D 4 101 ? 106.818 81.905  83.424  1.00 44.07  ? 101 TYR E CD2 1 
ATOM 5577 C CE1 . TYR D 4 101 ? 105.198 80.055  82.178  1.00 37.78  ? 101 TYR E CE1 1 
ATOM 5578 C CE2 . TYR D 4 101 ? 107.278 80.621  83.211  1.00 41.36  ? 101 TYR E CE2 1 
ATOM 5579 C CZ  . TYR D 4 101 ? 106.463 79.700  82.587  1.00 46.55  ? 101 TYR E CZ  1 
ATOM 5580 O OH  . TYR D 4 101 ? 106.916 78.418  82.371  1.00 40.43  ? 101 TYR E OH  1 
ATOM 5581 N N   . TYR D 4 102 ? 103.894 86.547  81.491  1.00 41.43  ? 102 TYR E N   1 
ATOM 5582 C CA  . TYR D 4 102 ? 103.035 87.691  81.744  1.00 33.99  ? 102 TYR E CA  1 
ATOM 5583 C C   . TYR D 4 102 ? 101.855 87.576  80.793  1.00 46.41  ? 102 TYR E C   1 
ATOM 5584 O O   . TYR D 4 102 ? 101.815 86.688  79.937  1.00 57.61  ? 102 TYR E O   1 
ATOM 5585 C CB  . TYR D 4 102 ? 103.784 89.018  81.570  1.00 32.66  ? 102 TYR E CB  1 
ATOM 5586 C CG  . TYR D 4 102 ? 104.424 89.203  80.212  1.00 28.94  ? 102 TYR E CG  1 
ATOM 5587 C CD1 . TYR D 4 102 ? 103.714 89.753  79.154  1.00 40.22  ? 102 TYR E CD1 1 
ATOM 5588 C CD2 . TYR D 4 102 ? 105.745 88.842  79.993  1.00 36.98  ? 102 TYR E CD2 1 
ATOM 5589 C CE1 . TYR D 4 102 ? 104.299 89.928  77.915  1.00 48.65  ? 102 TYR E CE1 1 
ATOM 5590 C CE2 . TYR D 4 102 ? 106.336 89.013  78.760  1.00 42.61  ? 102 TYR E CE2 1 
ATOM 5591 C CZ  . TYR D 4 102 ? 105.610 89.556  77.724  1.00 50.36  ? 102 TYR E CZ  1 
ATOM 5592 O OH  . TYR D 4 102 ? 106.198 89.727  76.492  1.00 48.39  ? 102 TYR E OH  1 
ATOM 5593 N N   . TYR D 4 103 ? 100.879 88.464  80.958  1.00 31.41  ? 103 TYR E N   1 
ATOM 5594 C CA  . TYR D 4 103 ? 99.702  88.413  80.100  1.00 33.57  ? 103 TYR E CA  1 
ATOM 5595 C C   . TYR D 4 103 ? 100.097 88.587  78.640  1.00 43.47  ? 103 TYR E C   1 
ATOM 5596 O O   . TYR D 4 103 ? 100.677 89.609  78.261  1.00 53.06  ? 103 TYR E O   1 
ATOM 5597 C CB  . TYR D 4 103 ? 98.682  89.475  80.494  1.00 27.08  ? 103 TYR E CB  1 
ATOM 5598 C CG  . TYR D 4 103 ? 97.576  89.576  79.473  1.00 29.46  ? 103 TYR E CG  1 
ATOM 5599 C CD1 . TYR D 4 103 ? 96.673  88.537  79.299  1.00 37.86  ? 103 TYR E CD1 1 
ATOM 5600 C CD2 . TYR D 4 103 ? 97.453  90.689  78.660  1.00 41.94  ? 103 TYR E CD2 1 
ATOM 5601 C CE1 . TYR D 4 103 ? 95.669  88.615  78.356  1.00 47.04  ? 103 TYR E CE1 1 
ATOM 5602 C CE2 . TYR D 4 103 ? 96.452  90.777  77.718  1.00 41.10  ? 103 TYR E CE2 1 
ATOM 5603 C CZ  . TYR D 4 103 ? 95.561  89.739  77.569  1.00 47.83  ? 103 TYR E CZ  1 
ATOM 5604 O OH  . TYR D 4 103 ? 94.560  89.823  76.630  1.00 56.46  ? 103 TYR E OH  1 
ATOM 5605 N N   . GLY D 4 104 ? 99.784  87.586  77.822  1.00 36.05  ? 104 GLY E N   1 
ATOM 5606 C CA  . GLY D 4 104 ? 100.083 87.631  76.409  1.00 36.43  ? 104 GLY E CA  1 
ATOM 5607 C C   . GLY D 4 104 ? 101.472 87.177  76.025  1.00 35.39  ? 104 GLY E C   1 
ATOM 5608 O O   . GLY D 4 104 ? 101.825 87.259  74.842  1.00 41.30  ? 104 GLY E O   1 
ATOM 5609 N N   . SER D 4 105 ? 102.270 86.700  76.976  1.00 38.03  ? 105 SER E N   1 
ATOM 5610 C CA  . SER D 4 105 ? 103.603 86.222  76.654  1.00 40.69  ? 105 SER E CA  1 
ATOM 5611 C C   . SER D 4 105 ? 103.519 84.880  75.928  1.00 52.60  ? 105 SER E C   1 
ATOM 5612 O O   . SER D 4 105 ? 102.471 84.229  75.879  1.00 63.09  ? 105 SER E O   1 
ATOM 5613 C CB  . SER D 4 105 ? 104.450 86.097  77.920  1.00 36.83  ? 105 SER E CB  1 
ATOM 5614 O OG  . SER D 4 105 ? 103.868 85.187  78.837  1.00 46.15  ? 105 SER E OG  1 
ATOM 5615 N N   . SER D 4 106 ? 104.650 84.462  75.359  1.00 55.89  ? 106 SER E N   1 
ATOM 5616 C CA  . SER D 4 106 ? 104.755 83.194  74.639  1.00 59.34  ? 106 SER E CA  1 
ATOM 5617 C C   . SER D 4 106 ? 105.819 82.337  75.312  1.00 59.89  ? 106 SER E C   1 
ATOM 5618 O O   . SER D 4 106 ? 107.002 82.389  74.939  1.00 59.76  ? 106 SER E O   1 
ATOM 5619 C CB  . SER D 4 106 ? 105.085 83.424  73.165  1.00 51.06  ? 106 SER E CB  1 
ATOM 5620 O OG  . SER D 4 106 ? 106.323 84.099  73.020  1.00 50.63  ? 106 SER E OG  1 
ATOM 5621 N N   . PRO D 4 107 ? 105.447 81.543  76.312  1.00 59.31  ? 107 PRO E N   1 
ATOM 5622 C CA  . PRO D 4 107 ? 106.422 80.658  76.956  1.00 55.54  ? 107 PRO E CA  1 
ATOM 5623 C C   . PRO D 4 107 ? 106.914 79.577  76.005  1.00 63.97  ? 107 PRO E C   1 
ATOM 5624 O O   . PRO D 4 107 ? 106.257 79.224  75.023  1.00 72.07  ? 107 PRO E O   1 
ATOM 5625 C CB  . PRO D 4 107 ? 105.636 80.048  78.123  1.00 57.03  ? 107 PRO E CB  1 
ATOM 5626 C CG  . PRO D 4 107 ? 104.489 80.984  78.345  1.00 60.30  ? 107 PRO E CG  1 
ATOM 5627 C CD  . PRO D 4 107 ? 104.142 81.517  76.992  1.00 60.65  ? 107 PRO E CD  1 
ATOM 5628 N N   . PHE D 4 108 ? 108.107 79.064  76.314  1.00 58.84  ? 108 PHE E N   1 
ATOM 5629 C CA  . PHE D 4 108 ? 108.737 77.981  75.558  1.00 55.57  ? 108 PHE E CA  1 
ATOM 5630 C C   . PHE D 4 108 ? 109.032 78.392  74.118  1.00 59.42  ? 108 PHE E C   1 
ATOM 5631 O O   . PHE D 4 108 ? 109.063 77.552  73.216  1.00 63.53  ? 108 PHE E O   1 
ATOM 5632 C CB  . PHE D 4 108 ? 107.886 76.708  75.581  1.00 58.50  ? 108 PHE E CB  1 
ATOM 5633 C CG  . PHE D 4 108 ? 107.776 76.073  76.935  1.00 55.95  ? 108 PHE E CG  1 
ATOM 5634 C CD1 . PHE D 4 108 ? 106.838 76.520  77.849  1.00 53.68  ? 108 PHE E CD1 1 
ATOM 5635 C CD2 . PHE D 4 108 ? 108.611 75.030  77.294  1.00 60.25  ? 108 PHE E CD2 1 
ATOM 5636 C CE1 . PHE D 4 108 ? 106.734 75.937  79.093  1.00 59.84  ? 108 PHE E CE1 1 
ATOM 5637 C CE2 . PHE D 4 108 ? 108.513 74.444  78.538  1.00 57.07  ? 108 PHE E CE2 1 
ATOM 5638 C CZ  . PHE D 4 108 ? 107.573 74.897  79.439  1.00 61.00  ? 108 PHE E CZ  1 
ATOM 5639 N N   . ASP D 4 109 ? 109.258 79.686  73.892  1.00 46.56  ? 109 ASP E N   1 
ATOM 5640 C CA  . ASP D 4 109 ? 109.442 80.181  72.533  1.00 54.64  ? 109 ASP E CA  1 
ATOM 5641 C C   . ASP D 4 109 ? 110.820 79.850  71.977  1.00 60.55  ? 109 ASP E C   1 
ATOM 5642 O O   . ASP D 4 109 ? 110.958 79.638  70.766  1.00 69.99  ? 109 ASP E O   1 
ATOM 5643 C CB  . ASP D 4 109 ? 109.201 81.692  72.486  1.00 55.50  ? 109 ASP E CB  1 
ATOM 5644 C CG  . ASP D 4 109 ? 110.325 82.485  73.125  1.00 63.31  ? 109 ASP E CG  1 
ATOM 5645 O OD1 . ASP D 4 109 ? 110.867 82.031  74.155  1.00 66.98  ? 109 ASP E OD1 1 
ATOM 5646 O OD2 . ASP D 4 109 ? 110.667 83.564  72.597  1.00 64.56  ? 109 ASP E OD2 1 
ATOM 5647 N N   . PHE D 4 110 ? 111.842 79.798  72.827  1.00 50.27  ? 110 PHE E N   1 
ATOM 5648 C CA  . PHE D 4 110 ? 113.207 79.530  72.399  1.00 49.02  ? 110 PHE E CA  1 
ATOM 5649 C C   . PHE D 4 110 ? 113.764 78.342  73.167  1.00 46.46  ? 110 PHE E C   1 
ATOM 5650 O O   . PHE D 4 110 ? 113.645 78.280  74.395  1.00 51.51  ? 110 PHE E O   1 
ATOM 5651 C CB  . PHE D 4 110 ? 114.098 80.759  72.602  1.00 46.80  ? 110 PHE E CB  1 
ATOM 5652 C CG  . PHE D 4 110 ? 115.428 80.660  71.914  1.00 58.69  ? 110 PHE E CG  1 
ATOM 5653 C CD1 . PHE D 4 110 ? 115.533 80.866  70.548  1.00 59.51  ? 110 PHE E CD1 1 
ATOM 5654 C CD2 . PHE D 4 110 ? 116.574 80.364  72.631  1.00 63.44  ? 110 PHE E CD2 1 
ATOM 5655 C CE1 . PHE D 4 110 ? 116.755 80.776  69.911  1.00 57.47  ? 110 PHE E CE1 1 
ATOM 5656 C CE2 . PHE D 4 110 ? 117.800 80.273  71.999  1.00 62.61  ? 110 PHE E CE2 1 
ATOM 5657 C CZ  . PHE D 4 110 ? 117.890 80.479  70.637  1.00 55.72  ? 110 PHE E CZ  1 
ATOM 5658 N N   . TRP D 4 111 ? 114.369 77.405  72.441  1.00 47.39  ? 111 TRP E N   1 
ATOM 5659 C CA  . TRP D 4 111 ? 115.001 76.231  73.020  1.00 49.47  ? 111 TRP E CA  1 
ATOM 5660 C C   . TRP D 4 111 ? 116.495 76.260  72.725  1.00 54.41  ? 111 TRP E C   1 
ATOM 5661 O O   . TRP D 4 111 ? 116.933 76.814  71.713  1.00 58.19  ? 111 TRP E O   1 
ATOM 5662 C CB  . TRP D 4 111 ? 114.382 74.936  72.473  1.00 56.48  ? 111 TRP E CB  1 
ATOM 5663 C CG  . TRP D 4 111 ? 112.995 74.675  72.978  1.00 59.81  ? 111 TRP E CG  1 
ATOM 5664 C CD1 . TRP D 4 111 ? 111.932 75.532  72.945  1.00 59.77  ? 111 TRP E CD1 1 
ATOM 5665 C CD2 . TRP D 4 111 ? 112.520 73.474  73.598  1.00 52.77  ? 111 TRP E CD2 1 
ATOM 5666 N NE1 . TRP D 4 111 ? 110.828 74.940  73.506  1.00 55.11  ? 111 TRP E NE1 1 
ATOM 5667 C CE2 . TRP D 4 111 ? 111.162 73.676  73.914  1.00 43.46  ? 111 TRP E CE2 1 
ATOM 5668 C CE3 . TRP D 4 111 ? 113.112 72.247  73.915  1.00 52.57  ? 111 TRP E CE3 1 
ATOM 5669 C CZ2 . TRP D 4 111 ? 110.388 72.700  74.531  1.00 50.08  ? 111 TRP E CZ2 1 
ATOM 5670 C CZ3 . TRP D 4 111 ? 112.342 71.281  74.529  1.00 60.68  ? 111 TRP E CZ3 1 
ATOM 5671 C CH2 . TRP D 4 111 ? 110.994 71.512  74.830  1.00 63.75  ? 111 TRP E CH2 1 
ATOM 5672 N N   . GLY D 4 112 ? 117.277 75.657  73.621  1.00 68.18  ? 112 GLY E N   1 
ATOM 5673 C CA  . GLY D 4 112 ? 118.699 75.528  73.390  1.00 71.71  ? 112 GLY E CA  1 
ATOM 5674 C C   . GLY D 4 112 ? 119.056 74.370  72.476  1.00 74.59  ? 112 GLY E C   1 
ATOM 5675 O O   . GLY D 4 112 ? 118.223 73.541  72.110  1.00 73.04  ? 112 GLY E O   1 
ATOM 5676 N N   . GLN D 4 113 ? 120.340 74.321  72.110  1.00 92.19  ? 113 GLN E N   1 
ATOM 5677 C CA  . GLN D 4 113 ? 120.820 73.267  71.222  1.00 92.44  ? 113 GLN E CA  1 
ATOM 5678 C C   . GLN D 4 113 ? 120.905 71.919  71.925  1.00 93.27  ? 113 GLN E C   1 
ATOM 5679 O O   . GLN D 4 113 ? 120.819 70.874  71.269  1.00 96.03  ? 113 GLN E O   1 
ATOM 5680 C CB  . GLN D 4 113 ? 122.180 73.655  70.640  1.00 92.24  ? 113 GLN E CB  1 
ATOM 5681 C CG  . GLN D 4 113 ? 122.112 74.793  69.632  1.00 90.48  ? 113 GLN E CG  1 
ATOM 5682 C CD  . GLN D 4 113 ? 121.437 74.382  68.336  1.00 93.31  ? 113 GLN E CD  1 
ATOM 5683 O OE1 . GLN D 4 113 ? 120.841 75.206  67.644  1.00 95.53  ? 113 GLN E OE1 1 
ATOM 5684 N NE2 . GLN D 4 113 ? 121.538 73.101  67.998  1.00 92.55  ? 113 GLN E NE2 1 
ATOM 5685 N N   . GLY D 4 114 ? 121.068 71.914  73.236  1.00 100.41 ? 114 GLY E N   1 
ATOM 5686 C CA  . GLY D 4 114 ? 121.039 70.670  73.976  1.00 100.77 ? 114 GLY E CA  1 
ATOM 5687 C C   . GLY D 4 114 ? 122.430 70.110  74.212  1.00 103.63 ? 114 GLY E C   1 
ATOM 5688 O O   . GLY D 4 114 ? 123.378 70.379  73.465  1.00 104.56 ? 114 GLY E O   1 
ATOM 5689 N N   . THR D 4 115 ? 122.559 69.316  75.273  1.00 110.37 ? 115 THR E N   1 
ATOM 5690 C CA  . THR D 4 115 ? 123.793 68.610  75.584  1.00 113.52 ? 115 THR E CA  1 
ATOM 5691 C C   . THR D 4 115 ? 123.492 67.136  75.814  1.00 112.03 ? 115 THR E C   1 
ATOM 5692 O O   . THR D 4 115 ? 122.457 66.786  76.388  1.00 110.40 ? 115 THR E O   1 
ATOM 5693 C CB  . THR D 4 115 ? 124.492 69.205  76.817  1.00 113.98 ? 115 THR E CB  1 
ATOM 5694 O OG1 . THR D 4 115 ? 125.620 68.393  77.168  1.00 113.32 ? 115 THR E OG1 1 
ATOM 5695 C CG2 . THR D 4 115 ? 123.535 69.282  77.997  1.00 113.00 ? 115 THR E CG2 1 
ATOM 5696 N N   . THR D 4 116 ? 124.397 66.277  75.353  1.00 123.63 ? 116 THR E N   1 
ATOM 5697 C CA  . THR D 4 116 ? 124.191 64.835  75.368  1.00 124.52 ? 116 THR E CA  1 
ATOM 5698 C C   . THR D 4 116 ? 124.843 64.233  76.606  1.00 125.21 ? 116 THR E C   1 
ATOM 5699 O O   . THR D 4 116 ? 126.029 64.463  76.864  1.00 126.65 ? 116 THR E O   1 
ATOM 5700 C CB  . THR D 4 116 ? 124.766 64.187  74.108  1.00 124.65 ? 116 THR E CB  1 
ATOM 5701 O OG1 . THR D 4 116 ? 124.193 64.801  72.947  1.00 126.16 ? 116 THR E OG1 1 
ATOM 5702 C CG2 . THR D 4 116 ? 124.462 62.696  74.089  1.00 123.73 ? 116 THR E CG2 1 
ATOM 5703 N N   . LEU D 4 117 ? 124.066 63.464  77.364  1.00 128.95 ? 117 LEU E N   1 
ATOM 5704 C CA  . LEU D 4 117 ? 124.556 62.734  78.525  1.00 129.10 ? 117 LEU E CA  1 
ATOM 5705 C C   . LEU D 4 117 ? 124.421 61.242  78.262  1.00 131.63 ? 117 LEU E C   1 
ATOM 5706 O O   . LEU D 4 117 ? 123.337 60.768  77.908  1.00 131.08 ? 117 LEU E O   1 
ATOM 5707 C CB  . LEU D 4 117 ? 123.788 63.123  79.790  1.00 126.83 ? 117 LEU E CB  1 
ATOM 5708 C CG  . LEU D 4 117 ? 124.220 62.422  81.080  1.00 129.32 ? 117 LEU E CG  1 
ATOM 5709 C CD1 . LEU D 4 117 ? 125.615 62.865  81.493  1.00 129.81 ? 117 LEU E CD1 1 
ATOM 5710 C CD2 . LEU D 4 117 ? 123.218 62.676  82.195  1.00 130.80 ? 117 LEU E CD2 1 
ATOM 5711 N N   . THR D 4 118 ? 125.519 60.509  78.430  1.00 145.71 ? 118 THR E N   1 
ATOM 5712 C CA  . THR D 4 118 ? 125.541 59.065  78.240  1.00 145.88 ? 118 THR E CA  1 
ATOM 5713 C C   . THR D 4 118 ? 126.008 58.392  79.522  1.00 145.49 ? 118 THR E C   1 
ATOM 5714 O O   . THR D 4 118 ? 127.041 58.769  80.085  1.00 144.63 ? 118 THR E O   1 
ATOM 5715 C CB  . THR D 4 118 ? 126.456 58.674  77.075  1.00 145.10 ? 118 THR E CB  1 
ATOM 5716 O OG1 . THR D 4 118 ? 126.010 59.322  75.877  1.00 144.08 ? 118 THR E OG1 1 
ATOM 5717 C CG2 . THR D 4 118 ? 126.441 57.167  76.866  1.00 145.28 ? 118 THR E CG2 1 
ATOM 5718 N N   . VAL D 4 119 ? 125.245 57.404  79.981  1.00 153.76 ? 119 VAL E N   1 
ATOM 5719 C CA  . VAL D 4 119 ? 125.556 56.648  81.189  1.00 154.69 ? 119 VAL E CA  1 
ATOM 5720 C C   . VAL D 4 119 ? 125.911 55.225  80.785  1.00 154.35 ? 119 VAL E C   1 
ATOM 5721 O O   . VAL D 4 119 ? 125.164 54.580  80.038  1.00 152.85 ? 119 VAL E O   1 
ATOM 5722 C CB  . VAL D 4 119 ? 124.383 56.665  82.184  1.00 154.37 ? 119 VAL E CB  1 
ATOM 5723 C CG1 . VAL D 4 119 ? 124.749 55.907  83.450  1.00 153.32 ? 119 VAL E CG1 1 
ATOM 5724 C CG2 . VAL D 4 119 ? 123.986 58.097  82.505  1.00 153.45 ? 119 VAL E CG2 1 
ATOM 5725 N N   . SER D 4 120 ? 127.046 54.737  81.277  1.00 158.16 ? 120 SER E N   1 
ATOM 5726 C CA  . SER D 4 120 ? 127.533 53.408  80.920  1.00 156.90 ? 120 SER E CA  1 
ATOM 5727 C C   . SER D 4 120 ? 126.655 52.305  81.507  1.00 156.50 ? 120 SER E C   1 
ATOM 5728 O O   . SER D 4 120 ? 125.645 52.575  82.157  1.00 156.69 ? 120 SER E O   1 
ATOM 5729 C CB  . SER D 4 120 ? 128.978 53.227  81.387  1.00 155.99 ? 120 SER E CB  1 
ATOM 5730 O OG  . SER D 4 120 ? 129.834 54.179  80.780  1.00 156.14 ? 120 SER E OG  1 
ATOM 5731 N N   . ASP D 4 137 ? 99.799  63.032  87.382  1.00 119.38 ? 137 ASP E N   1 
ATOM 5732 C CA  . ASP D 4 137 ? 100.431 63.329  86.102  1.00 120.79 ? 137 ASP E CA  1 
ATOM 5733 C C   . ASP D 4 137 ? 99.443  63.194  84.948  1.00 119.25 ? 137 ASP E C   1 
ATOM 5734 O O   . ASP D 4 137 ? 98.879  62.123  84.723  1.00 120.44 ? 137 ASP E O   1 
ATOM 5735 C CB  . ASP D 4 137 ? 101.632 62.409  85.871  1.00 122.25 ? 137 ASP E CB  1 
ATOM 5736 C CG  . ASP D 4 137 ? 102.739 62.627  86.883  1.00 123.09 ? 137 ASP E CG  1 
ATOM 5737 O OD1 . ASP D 4 137 ? 102.461 62.556  88.098  1.00 121.65 ? 137 ASP E OD1 1 
ATOM 5738 O OD2 . ASP D 4 137 ? 103.891 62.864  86.461  1.00 121.93 ? 137 ASP E OD2 1 
ATOM 5739 N N   . ILE D 4 138 ? 99.239  64.290  84.217  1.00 98.98  ? 138 ILE E N   1 
ATOM 5740 C CA  . ILE D 4 138 ? 98.377  64.261  83.042  1.00 98.76  ? 138 ILE E CA  1 
ATOM 5741 C C   . ILE D 4 138 ? 99.074  63.486  81.934  1.00 100.85 ? 138 ILE E C   1 
ATOM 5742 O O   . ILE D 4 138 ? 100.250 63.725  81.632  1.00 104.17 ? 138 ILE E O   1 
ATOM 5743 C CB  . ILE D 4 138 ? 98.025  65.688  82.597  1.00 98.49  ? 138 ILE E CB  1 
ATOM 5744 C CG1 . ILE D 4 138 ? 97.268  66.419  83.709  1.00 101.16 ? 138 ILE E CG1 1 
ATOM 5745 C CG2 . ILE D 4 138 ? 97.203  65.664  81.317  1.00 100.36 ? 138 ILE E CG2 1 
ATOM 5746 C CD1 . ILE D 4 138 ? 96.824  67.815  83.331  1.00 100.70 ? 138 ILE E CD1 1 
ATOM 5747 N N   . VAL D 4 139 ? 98.354  62.553  81.320  1.00 101.16 ? 139 VAL E N   1 
ATOM 5748 C CA  . VAL D 4 139 ? 98.902  61.707  80.266  1.00 103.55 ? 139 VAL E CA  1 
ATOM 5749 C C   . VAL D 4 139 ? 98.553  62.318  78.916  1.00 104.73 ? 139 VAL E C   1 
ATOM 5750 O O   . VAL D 4 139 ? 97.373  62.495  78.590  1.00 106.88 ? 139 VAL E O   1 
ATOM 5751 C CB  . VAL D 4 139 ? 98.373  60.268  80.372  1.00 102.90 ? 139 VAL E CB  1 
ATOM 5752 C CG1 . VAL D 4 139 ? 98.974  59.401  79.275  1.00 102.11 ? 139 VAL E CG1 1 
ATOM 5753 C CG2 . VAL D 4 139 ? 98.678  59.691  81.745  1.00 101.81 ? 139 VAL E CG2 1 
ATOM 5754 N N   . MET D 4 140 ? 99.579  62.641  78.133  1.00 100.69 ? 140 MET E N   1 
ATOM 5755 C CA  . MET D 4 140 ? 99.410  63.166  76.784  1.00 102.34 ? 140 MET E CA  1 
ATOM 5756 C C   . MET D 4 140 ? 99.681  62.043  75.792  1.00 102.88 ? 140 MET E C   1 
ATOM 5757 O O   . MET D 4 140 ? 100.761 61.441  75.810  1.00 102.59 ? 140 MET E O   1 
ATOM 5758 C CB  . MET D 4 140 ? 100.350 64.345  76.535  1.00 101.52 ? 140 MET E CB  1 
ATOM 5759 C CG  . MET D 4 140 ? 100.293 65.423  77.605  1.00 101.16 ? 140 MET E CG  1 
ATOM 5760 S SD  . MET D 4 140 ? 98.660  66.172  77.749  1.00 98.90  ? 140 MET E SD  1 
ATOM 5761 C CE  . MET D 4 140 ? 98.472  66.888  76.119  1.00 101.00 ? 140 MET E CE  1 
ATOM 5762 N N   . THR D 4 141 ? 98.708  61.765  74.928  1.00 104.37 ? 141 THR E N   1 
ATOM 5763 C CA  . THR D 4 141 ? 98.759  60.624  74.025  1.00 104.73 ? 141 THR E CA  1 
ATOM 5764 C C   . THR D 4 141 ? 98.783  61.103  72.581  1.00 105.65 ? 141 THR E C   1 
ATOM 5765 O O   . THR D 4 141 ? 97.926  61.892  72.168  1.00 106.06 ? 141 THR E O   1 
ATOM 5766 C CB  . THR D 4 141 ? 97.564  59.691  74.248  1.00 104.19 ? 141 THR E CB  1 
ATOM 5767 O OG1 . THR D 4 141 ? 97.549  59.250  75.611  1.00 102.30 ? 141 THR E OG1 1 
ATOM 5768 C CG2 . THR D 4 141 ? 97.655  58.480  73.331  1.00 103.26 ? 141 THR E CG2 1 
ATOM 5769 N N   . GLN D 4 142 ? 99.766  60.625  71.821  1.00 101.73 ? 142 GLN E N   1 
ATOM 5770 C CA  . GLN D 4 142 ? 99.842  60.819  70.374  1.00 102.69 ? 142 GLN E CA  1 
ATOM 5771 C C   . GLN D 4 142 ? 99.934  59.428  69.752  1.00 98.85  ? 142 GLN E C   1 
ATOM 5772 O O   . GLN D 4 142 ? 101.030 58.919  69.502  1.00 97.13  ? 142 GLN E O   1 
ATOM 5773 C CB  . GLN D 4 142 ? 101.030 61.699  69.984  1.00 102.17 ? 142 GLN E CB  1 
ATOM 5774 C CG  . GLN D 4 142 ? 101.052 63.051  70.676  1.00 98.29  ? 142 GLN E CG  1 
ATOM 5775 C CD  . GLN D 4 142 ? 102.120 63.973  70.121  1.00 96.62  ? 142 GLN E CD  1 
ATOM 5776 O OE1 . GLN D 4 142 ? 102.861 64.606  70.872  1.00 101.43 ? 142 GLN E OE1 1 
ATOM 5777 N NE2 . GLN D 4 142 ? 102.200 64.055  68.798  1.00 93.02  ? 142 GLN E NE2 1 
ATOM 5778 N N   . ALA D 4 143 ? 98.772  58.814  69.513  1.00 106.54 ? 143 ALA E N   1 
ATOM 5779 C CA  . ALA D 4 143 ? 98.739  57.428  69.057  1.00 108.19 ? 143 ALA E CA  1 
ATOM 5780 C C   . ALA D 4 143 ? 99.399  57.266  67.693  1.00 109.92 ? 143 ALA E C   1 
ATOM 5781 O O   . ALA D 4 143 ? 100.132 56.296  67.462  1.00 110.60 ? 143 ALA E O   1 
ATOM 5782 C CB  . ALA D 4 143 ? 97.296  56.925  69.016  1.00 107.45 ? 143 ALA E CB  1 
ATOM 5783 N N   . THR D 4 144 ? 99.156  58.200  66.777  1.00 114.67 ? 144 THR E N   1 
ATOM 5784 C CA  . THR D 4 144 ? 99.741  58.119  65.442  1.00 115.80 ? 144 THR E CA  1 
ATOM 5785 C C   . THR D 4 144 ? 101.228 58.444  65.527  1.00 115.04 ? 144 THR E C   1 
ATOM 5786 O O   . THR D 4 144 ? 101.609 59.609  65.683  1.00 112.92 ? 144 THR E O   1 
ATOM 5787 C CB  . THR D 4 144 ? 99.024  59.070  64.490  1.00 114.62 ? 144 THR E CB  1 
ATOM 5788 O OG1 . THR D 4 144 ? 97.610  58.992  64.711  1.00 115.10 ? 144 THR E OG1 1 
ATOM 5789 C CG2 . THR D 4 144 ? 99.318  58.691  63.049  1.00 113.33 ? 144 THR E CG2 1 
ATOM 5790 N N   . SER D 4 145 ? 102.070 57.414  65.421  1.00 119.20 ? 145 SER E N   1 
ATOM 5791 C CA  . SER D 4 145 ? 103.511 57.624  65.526  1.00 116.81 ? 145 SER E CA  1 
ATOM 5792 C C   . SER D 4 145 ? 104.081 58.273  64.271  1.00 116.98 ? 145 SER E C   1 
ATOM 5793 O O   . SER D 4 145 ? 104.937 59.161  64.362  1.00 115.78 ? 145 SER E O   1 
ATOM 5794 C CB  . SER D 4 145 ? 104.212 56.295  65.807  1.00 117.42 ? 145 SER E CB  1 
ATOM 5795 O OG  . SER D 4 145 ? 103.761 55.729  67.025  1.00 115.88 ? 145 SER E OG  1 
ATOM 5796 N N   . SER D 4 146 ? 103.626 57.850  63.093  1.00 124.29 ? 146 SER E N   1 
ATOM 5797 C CA  . SER D 4 146 ? 104.160 58.368  61.843  1.00 124.59 ? 146 SER E CA  1 
ATOM 5798 C C   . SER D 4 146 ? 103.028 58.630  60.861  1.00 127.18 ? 146 SER E C   1 
ATOM 5799 O O   . SER D 4 146 ? 101.990 57.964  60.889  1.00 126.36 ? 146 SER E O   1 
ATOM 5800 C CB  . SER D 4 146 ? 105.176 57.401  61.220  1.00 124.31 ? 146 SER E CB  1 
ATOM 5801 O OG  . SER D 4 146 ? 104.584 56.143  60.947  1.00 123.53 ? 146 SER E OG  1 
ATOM 5802 N N   . VAL D 4 147 ? 103.245 59.611  59.989  1.00 138.07 ? 147 VAL E N   1 
ATOM 5803 C CA  . VAL D 4 147 ? 102.283 59.982  58.953  1.00 137.04 ? 147 VAL E CA  1 
ATOM 5804 C C   . VAL D 4 147 ? 103.039 60.219  57.651  1.00 136.00 ? 147 VAL E C   1 
ATOM 5805 O O   . VAL D 4 147 ? 103.882 61.125  57.585  1.00 134.72 ? 147 VAL E O   1 
ATOM 5806 C CB  . VAL D 4 147 ? 101.473 61.227  59.347  1.00 138.59 ? 147 VAL E CB  1 
ATOM 5807 C CG1 . VAL D 4 147 ? 100.623 61.696  58.176  1.00 137.69 ? 147 VAL E CG1 1 
ATOM 5808 C CG2 . VAL D 4 147 ? 100.597 60.944  60.555  1.00 135.88 ? 147 VAL E CG2 1 
ATOM 5809 N N   . PRO D 4 148 ? 102.782 59.443  56.598  1.00 135.52 ? 148 PRO E N   1 
ATOM 5810 C CA  . PRO D 4 148 ? 103.425 59.726  55.308  1.00 136.47 ? 148 PRO E CA  1 
ATOM 5811 C C   . PRO D 4 148 ? 102.788 60.942  54.653  1.00 136.96 ? 148 PRO E C   1 
ATOM 5812 O O   . PRO D 4 148 ? 101.566 61.016  54.500  1.00 135.94 ? 148 PRO E O   1 
ATOM 5813 C CB  . PRO D 4 148 ? 103.177 58.448  54.499  1.00 136.49 ? 148 PRO E CB  1 
ATOM 5814 C CG  . PRO D 4 148 ? 101.930 57.875  55.090  1.00 136.29 ? 148 PRO E CG  1 
ATOM 5815 C CD  . PRO D 4 148 ? 101.958 58.222  56.555  1.00 134.79 ? 148 PRO E CD  1 
ATOM 5816 N N   . VAL D 4 149 ? 103.627 61.904  54.266  1.00 136.17 ? 149 VAL E N   1 
ATOM 5817 C CA  . VAL D 4 149 ? 103.162 63.179  53.742  1.00 135.18 ? 149 VAL E CA  1 
ATOM 5818 C C   . VAL D 4 149 ? 103.901 63.494  52.449  1.00 134.03 ? 149 VAL E C   1 
ATOM 5819 O O   . VAL D 4 149 ? 104.971 62.952  52.163  1.00 134.20 ? 149 VAL E O   1 
ATOM 5820 C CB  . VAL D 4 149 ? 103.347 64.333  54.753  1.00 133.91 ? 149 VAL E CB  1 
ATOM 5821 C CG1 . VAL D 4 149 ? 102.594 64.042  56.042  1.00 133.98 ? 149 VAL E CG1 1 
ATOM 5822 C CG2 . VAL D 4 149 ? 104.825 64.563  55.031  1.00 133.11 ? 149 VAL E CG2 1 
ATOM 5823 N N   . THR D 4 150 ? 103.305 64.386  51.665  1.00 133.30 ? 150 THR E N   1 
ATOM 5824 C CA  . THR D 4 150 ? 103.882 64.906  50.438  1.00 134.73 ? 150 THR E CA  1 
ATOM 5825 C C   . THR D 4 150 ? 103.819 66.425  50.454  1.00 135.11 ? 150 THR E C   1 
ATOM 5826 O O   . THR D 4 150 ? 102.888 67.005  51.021  1.00 135.85 ? 150 THR E O   1 
ATOM 5827 C CB  . THR D 4 150 ? 103.143 64.376  49.199  1.00 133.16 ? 150 THR E CB  1 
ATOM 5828 O OG1 . THR D 4 150 ? 101.752 64.712  49.289  1.00 132.82 ? 150 THR E OG1 1 
ATOM 5829 C CG2 . THR D 4 150 ? 103.292 62.865  49.091  1.00 131.35 ? 150 THR E CG2 1 
ATOM 5830 N N   . PRO D 4 151 ? 104.805 67.094  49.855  1.00 127.41 ? 151 PRO E N   1 
ATOM 5831 C CA  . PRO D 4 151 ? 104.825 68.562  49.888  1.00 125.48 ? 151 PRO E CA  1 
ATOM 5832 C C   . PRO D 4 151 ? 103.594 69.156  49.216  1.00 124.15 ? 151 PRO E C   1 
ATOM 5833 O O   . PRO D 4 151 ? 103.086 68.628  48.225  1.00 124.58 ? 151 PRO E O   1 
ATOM 5834 C CB  . PRO D 4 151 ? 106.108 68.916  49.127  1.00 123.55 ? 151 PRO E CB  1 
ATOM 5835 C CG  . PRO D 4 151 ? 106.966 67.700  49.248  1.00 124.49 ? 151 PRO E CG  1 
ATOM 5836 C CD  . PRO D 4 151 ? 106.018 66.539  49.232  1.00 124.77 ? 151 PRO E CD  1 
ATOM 5837 N N   . GLY D 4 152 ? 103.119 70.271  49.770  1.00 112.97 ? 152 GLY E N   1 
ATOM 5838 C CA  . GLY D 4 152 ? 101.973 70.971  49.232  1.00 111.97 ? 152 GLY E CA  1 
ATOM 5839 C C   . GLY D 4 152 ? 100.620 70.436  49.647  1.00 114.84 ? 152 GLY E C   1 
ATOM 5840 O O   . GLY D 4 152 ? 99.599  70.970  49.194  1.00 114.28 ? 152 GLY E O   1 
ATOM 5841 N N   . GLU D 4 153 ? 100.569 69.407  50.489  1.00 122.55 ? 153 GLU E N   1 
ATOM 5842 C CA  . GLU D 4 153 ? 99.315  68.801  50.910  1.00 120.55 ? 153 GLU E CA  1 
ATOM 5843 C C   . GLU D 4 153 ? 99.038  69.137  52.370  1.00 121.32 ? 153 GLU E C   1 
ATOM 5844 O O   . GLU D 4 153 ? 99.960  69.263  53.181  1.00 120.07 ? 153 GLU E O   1 
ATOM 5845 C CB  . GLU D 4 153 ? 99.355  67.281  50.711  1.00 119.22 ? 153 GLU E CB  1 
ATOM 5846 C CG  . GLU D 4 153 ? 98.008  66.587  50.834  1.00 120.22 ? 153 GLU E CG  1 
ATOM 5847 C CD  . GLU D 4 153 ? 97.821  65.914  52.178  1.00 122.02 ? 153 GLU E CD  1 
ATOM 5848 O OE1 . GLU D 4 153 ? 98.787  65.888  52.970  1.00 121.64 ? 153 GLU E OE1 1 
ATOM 5849 O OE2 . GLU D 4 153 ? 96.710  65.409  52.444  1.00 121.07 ? 153 GLU E OE2 1 
ATOM 5850 N N   . SER D 4 154 ? 97.757  69.278  52.701  1.00 116.96 ? 154 SER E N   1 
ATOM 5851 C CA  . SER D 4 154 ? 97.360  69.667  54.048  1.00 115.73 ? 154 SER E CA  1 
ATOM 5852 C C   . SER D 4 154 ? 97.404  68.473  54.992  1.00 115.00 ? 154 SER E C   1 
ATOM 5853 O O   . SER D 4 154 ? 96.940  67.379  54.658  1.00 113.95 ? 154 SER E O   1 
ATOM 5854 C CB  . SER D 4 154 ? 95.956  70.273  54.036  1.00 114.41 ? 154 SER E CB  1 
ATOM 5855 O OG  . SER D 4 154 ? 95.904  71.422  53.208  1.00 114.84 ? 154 SER E OG  1 
ATOM 5856 N N   . VAL D 4 155 ? 97.957  68.692  56.183  1.00 117.15 ? 155 VAL E N   1 
ATOM 5857 C CA  . VAL D 4 155 ? 98.126  67.646  57.184  1.00 119.16 ? 155 VAL E CA  1 
ATOM 5858 C C   . VAL D 4 155 ? 97.509  68.115  58.494  1.00 117.72 ? 155 VAL E C   1 
ATOM 5859 O O   . VAL D 4 155 ? 97.633  69.287  58.866  1.00 115.18 ? 155 VAL E O   1 
ATOM 5860 C CB  . VAL D 4 155 ? 99.615  67.285  57.380  1.00 119.19 ? 155 VAL E CB  1 
ATOM 5861 C CG1 . VAL D 4 155 ? 99.766  66.139  58.370  1.00 118.45 ? 155 VAL E CG1 1 
ATOM 5862 C CG2 . VAL D 4 155 ? 100.253 66.924  56.048  1.00 119.66 ? 155 VAL E CG2 1 
ATOM 5863 N N   . SER D 4 156 ? 96.842  67.197  59.192  1.00 115.79 ? 156 SER E N   1 
ATOM 5864 C CA  . SER D 4 156 ? 96.277  67.454  60.509  1.00 115.24 ? 156 SER E CA  1 
ATOM 5865 C C   . SER D 4 156 ? 96.872  66.465  61.501  1.00 114.07 ? 156 SER E C   1 
ATOM 5866 O O   . SER D 4 156 ? 96.963  65.268  61.211  1.00 114.91 ? 156 SER E O   1 
ATOM 5867 C CB  . SER D 4 156 ? 94.750  67.341  60.490  1.00 115.51 ? 156 SER E CB  1 
ATOM 5868 O OG  . SER D 4 156 ? 94.178  68.311  59.631  1.00 115.12 ? 156 SER E OG  1 
ATOM 5869 N N   . ILE D 4 157 ? 97.275  66.968  62.666  1.00 101.98 ? 157 ILE E N   1 
ATOM 5870 C CA  . ILE D 4 157 ? 97.869  66.157  63.723  1.00 102.08 ? 157 ILE E CA  1 
ATOM 5871 C C   . ILE D 4 157 ? 96.997  66.266  64.966  1.00 100.79 ? 157 ILE E C   1 
ATOM 5872 O O   . ILE D 4 157 ? 96.589  67.368  65.349  1.00 100.16 ? 157 ILE E O   1 
ATOM 5873 C CB  . ILE D 4 157 ? 99.314  66.595  64.025  1.00 104.68 ? 157 ILE E CB  1 
ATOM 5874 C CG1 . ILE D 4 157 ? 100.171 66.495  62.761  1.00 102.64 ? 157 ILE E CG1 1 
ATOM 5875 C CG2 . ILE D 4 157 ? 99.911  65.747  65.135  1.00 103.53 ? 157 ILE E CG2 1 
ATOM 5876 C CD1 . ILE D 4 157 ? 101.613 66.896  62.967  1.00 104.32 ? 157 ILE E CD1 1 
ATOM 5877 N N   . SER D 4 158 ? 96.720  65.126  65.594  1.00 109.45 ? 158 SER E N   1 
ATOM 5878 C CA  . SER D 4 158 ? 95.810  65.042  66.728  1.00 112.35 ? 158 SER E CA  1 
ATOM 5879 C C   . SER D 4 158 ? 96.587  64.790  68.013  1.00 111.03 ? 158 SER E C   1 
ATOM 5880 O O   . SER D 4 158 ? 97.594  64.074  68.014  1.00 111.02 ? 158 SER E O   1 
ATOM 5881 C CB  . SER D 4 158 ? 94.775  63.933  66.520  1.00 111.80 ? 158 SER E CB  1 
ATOM 5882 O OG  . SER D 4 158 ? 93.974  64.190  65.380  1.00 112.52 ? 158 SER E OG  1 
ATOM 5883 N N   . CYS D 4 159 ? 96.109  65.384  69.105  1.00 113.05 ? 159 CYS E N   1 
ATOM 5884 C CA  . CYS D 4 159 ? 96.690  65.204  70.428  1.00 113.10 ? 159 CYS E CA  1 
ATOM 5885 C C   . CYS D 4 159 ? 95.568  64.999  71.435  1.00 114.20 ? 159 CYS E C   1 
ATOM 5886 O O   . CYS D 4 159 ? 94.472  65.543  71.284  1.00 114.87 ? 159 CYS E O   1 
ATOM 5887 C CB  . CYS D 4 159 ? 97.549  66.410  70.832  1.00 115.93 ? 159 CYS E CB  1 
ATOM 5888 S SG  . CYS D 4 159 ? 98.322  66.304  72.464  1.00 121.17 ? 159 CYS E SG  1 
ATOM 5889 N N   . ARG D 4 160 ? 95.854  64.208  72.468  1.00 114.97 ? 160 ARG E N   1 
ATOM 5890 C CA  . ARG D 4 160 ? 94.884  63.915  73.511  1.00 114.38 ? 160 ARG E CA  1 
ATOM 5891 C C   . ARG D 4 160 ? 95.508  64.126  74.882  1.00 113.26 ? 160 ARG E C   1 
ATOM 5892 O O   . ARG D 4 160 ? 96.720  63.980  75.063  1.00 112.95 ? 160 ARG E O   1 
ATOM 5893 C CB  . ARG D 4 160 ? 94.363  62.474  73.402  1.00 111.30 ? 160 ARG E CB  1 
ATOM 5894 C CG  . ARG D 4 160 ? 93.584  62.184  72.130  1.00 113.21 ? 160 ARG E CG  1 
ATOM 5895 C CD  . ARG D 4 160 ? 93.220  60.709  72.018  1.00 113.94 ? 160 ARG E CD  1 
ATOM 5896 N NE  . ARG D 4 160 ? 92.383  60.254  73.123  1.00 116.05 ? 160 ARG E NE  1 
ATOM 5897 C CZ  . ARG D 4 160 ? 92.825  59.556  74.160  1.00 116.32 ? 160 ARG E CZ  1 
ATOM 5898 N NH1 . ARG D 4 160 ? 94.097  59.210  74.269  1.00 116.03 ? 160 ARG E NH1 1 
ATOM 5899 N NH2 . ARG D 4 160 ? 91.969  59.197  75.113  1.00 115.25 ? 160 ARG E NH2 1 
ATOM 5900 N N   . SER D 4 161 ? 94.661  64.478  75.847  1.00 111.84 ? 161 SER E N   1 
ATOM 5901 C CA  . SER D 4 161 ? 95.072  64.692  77.227  1.00 111.64 ? 161 SER E CA  1 
ATOM 5902 C C   . SER D 4 161 ? 94.136  63.935  78.157  1.00 109.40 ? 161 SER E C   1 
ATOM 5903 O O   . SER D 4 161 ? 92.936  63.827  77.889  1.00 108.81 ? 161 SER E O   1 
ATOM 5904 C CB  . SER D 4 161 ? 95.072  66.184  77.583  1.00 111.97 ? 161 SER E CB  1 
ATOM 5905 O OG  . SER D 4 161 ? 93.778  66.743  77.433  1.00 112.23 ? 161 SER E OG  1 
ATOM 5906 N N   . SER D 4 162 ? 94.693  63.405  79.249  1.00 102.15 ? 162 SER E N   1 
ATOM 5907 C CA  . SER D 4 162 ? 93.871  62.697  80.224  1.00 102.33 ? 162 SER E CA  1 
ATOM 5908 C C   . SER D 4 162 ? 92.923  63.639  80.957  1.00 101.92 ? 162 SER E C   1 
ATOM 5909 O O   . SER D 4 162 ? 91.811  63.237  81.319  1.00 103.77 ? 162 SER E O   1 
ATOM 5910 C CB  . SER D 4 162 ? 94.760  61.957  81.224  1.00 103.62 ? 162 SER E CB  1 
ATOM 5911 O OG  . SER D 4 162 ? 95.574  62.861  81.949  1.00 103.71 ? 162 SER E OG  1 
ATOM 5912 N N   . LYS D 4 163 ? 93.337  64.881  81.184  1.00 97.74  ? 163 LYS E N   1 
ATOM 5913 C CA  . LYS D 4 163 ? 92.517  65.888  81.838  1.00 99.62  ? 163 LYS E CA  1 
ATOM 5914 C C   . LYS D 4 163 ? 92.198  67.019  80.867  1.00 102.06 ? 163 LYS E C   1 
ATOM 5915 O O   . LYS D 4 163 ? 92.914  67.248  79.889  1.00 101.26 ? 163 LYS E O   1 
ATOM 5916 C CB  . LYS D 4 163 ? 93.227  66.439  83.081  1.00 96.62  ? 163 LYS E CB  1 
ATOM 5917 C CG  . LYS D 4 163 ? 92.330  67.200  84.045  1.00 97.61  ? 163 LYS E CG  1 
ATOM 5918 C CD  . LYS D 4 163 ? 93.140  67.863  85.146  1.00 97.50  ? 163 LYS E CD  1 
ATOM 5919 C CE  . LYS D 4 163 ? 93.933  66.837  85.939  1.00 98.83  ? 163 LYS E CE  1 
ATOM 5920 N NZ  . LYS D 4 163 ? 94.755  67.471  87.006  1.00 97.37  ? 163 LYS E NZ  1 
ATOM 5921 N N   . SER D 4 164 ? 91.107  67.729  81.150  1.00 109.58 ? 164 SER E N   1 
ATOM 5922 C CA  . SER D 4 164 ? 90.749  68.903  80.364  1.00 109.64 ? 164 SER E CA  1 
ATOM 5923 C C   . SER D 4 164 ? 91.763  70.011  80.621  1.00 107.45 ? 164 SER E C   1 
ATOM 5924 O O   . SER D 4 164 ? 91.986  70.404  81.771  1.00 105.89 ? 164 SER E O   1 
ATOM 5925 C CB  . SER D 4 164 ? 89.339  69.367  80.717  1.00 108.93 ? 164 SER E CB  1 
ATOM 5926 O OG  . SER D 4 164 ? 88.968  70.503  79.955  1.00 108.29 ? 164 SER E OG  1 
ATOM 5927 N N   . LEU D 4 165 ? 92.371  70.516  79.552  1.00 92.07  ? 165 LEU E N   1 
ATOM 5928 C CA  . LEU D 4 165 ? 93.362  71.581  79.635  1.00 89.80  ? 165 LEU E CA  1 
ATOM 5929 C C   . LEU D 4 165 ? 92.762  72.980  79.664  1.00 92.14  ? 165 LEU E C   1 
ATOM 5930 O O   . LEU D 4 165 ? 93.513  73.953  79.788  1.00 96.17  ? 165 LEU E O   1 
ATOM 5931 C CB  . LEU D 4 165 ? 94.337  71.473  78.459  1.00 88.22  ? 165 LEU E CB  1 
ATOM 5932 C CG  . LEU D 4 165 ? 95.169  70.192  78.407  1.00 89.21  ? 165 LEU E CG  1 
ATOM 5933 C CD1 . LEU D 4 165 ? 96.158  70.240  77.254  1.00 91.85  ? 165 LEU E CD1 1 
ATOM 5934 C CD2 . LEU D 4 165 ? 95.887  69.973  79.728  1.00 87.64  ? 165 LEU E CD2 1 
ATOM 5935 N N   . LEU D 4 166 ? 91.445  73.119  79.554  1.00 81.82  ? 166 LEU E N   1 
ATOM 5936 C CA  . LEU D 4 166 ? 90.827  74.437  79.621  1.00 78.24  ? 166 LEU E CA  1 
ATOM 5937 C C   . LEU D 4 166 ? 90.710  74.887  81.072  1.00 75.76  ? 166 LEU E C   1 
ATOM 5938 O O   . LEU D 4 166 ? 90.042  74.234  81.881  1.00 78.63  ? 166 LEU E O   1 
ATOM 5939 C CB  . LEU D 4 166 ? 89.454  74.413  78.953  1.00 77.51  ? 166 LEU E CB  1 
ATOM 5940 C CG  . LEU D 4 166 ? 88.643  75.705  79.051  1.00 74.22  ? 166 LEU E CG  1 
ATOM 5941 C CD1 . LEU D 4 166 ? 89.392  76.855  78.401  1.00 80.16  ? 166 LEU E CD1 1 
ATOM 5942 C CD2 . LEU D 4 166 ? 87.275  75.525  78.412  1.00 74.39  ? 166 LEU E CD2 1 
ATOM 5943 N N   . HIS D 4 167 ? 91.362  75.999  81.400  1.00 73.90  ? 167 HIS E N   1 
ATOM 5944 C CA  . HIS D 4 167 ? 91.304  76.571  82.735  1.00 74.14  ? 167 HIS E CA  1 
ATOM 5945 C C   . HIS D 4 167 ? 90.138  77.552  82.851  1.00 75.22  ? 167 HIS E C   1 
ATOM 5946 O O   . HIS D 4 167 ? 89.548  77.984  81.859  1.00 73.56  ? 167 HIS E O   1 
ATOM 5947 C CB  . HIS D 4 167 ? 92.623  77.255  83.091  1.00 72.31  ? 167 HIS E CB  1 
ATOM 5948 C CG  . HIS D 4 167 ? 92.853  77.387  84.564  1.00 69.20  ? 167 HIS E CG  1 
ATOM 5949 N ND1 . HIS D 4 167 ? 92.576  78.543  85.261  1.00 69.37  ? 167 HIS E ND1 1 
ATOM 5950 C CD2 . HIS D 4 167 ? 93.314  76.499  85.477  1.00 72.00  ? 167 HIS E CD2 1 
ATOM 5951 C CE1 . HIS D 4 167 ? 92.869  78.366  86.537  1.00 73.93  ? 167 HIS E CE1 1 
ATOM 5952 N NE2 . HIS D 4 167 ? 93.318  77.134  86.695  1.00 74.43  ? 167 HIS E NE2 1 
ATOM 5953 N N   . SER D 4 168 ? 89.812  77.903  84.096  1.00 72.80  ? 168 SER E N   1 
ATOM 5954 C CA  . SER D 4 168 ? 88.715  78.820  84.379  1.00 73.18  ? 168 SER E CA  1 
ATOM 5955 C C   . SER D 4 168 ? 88.983  80.248  83.920  1.00 72.00  ? 168 SER E C   1 
ATOM 5956 O O   . SER D 4 168 ? 88.046  81.054  83.899  1.00 74.47  ? 168 SER E O   1 
ATOM 5957 C CB  . SER D 4 168 ? 88.410  78.816  85.878  1.00 74.45  ? 168 SER E CB  1 
ATOM 5958 O OG  . SER D 4 168 ? 89.541  79.223  86.627  1.00 75.06  ? 168 SER E OG  1 
ATOM 5959 N N   . ASN D 4 169 ? 90.218  80.587  83.556  1.00 75.40  ? 169 ASN E N   1 
ATOM 5960 C CA  . ASN D 4 169 ? 90.527  81.923  83.062  1.00 74.13  ? 169 ASN E CA  1 
ATOM 5961 C C   . ASN D 4 169 ? 90.353  82.062  81.555  1.00 75.87  ? 169 ASN E C   1 
ATOM 5962 O O   . ASN D 4 169 ? 90.594  83.147  81.017  1.00 78.10  ? 169 ASN E O   1 
ATOM 5963 C CB  . ASN D 4 169 ? 91.960  82.306  83.451  1.00 72.89  ? 169 ASN E CB  1 
ATOM 5964 C CG  . ASN D 4 169 ? 92.978  81.251  83.051  1.00 74.42  ? 169 ASN E CG  1 
ATOM 5965 O OD1 . ASN D 4 169 ? 92.713  80.404  82.198  1.00 78.40  ? 169 ASN E OD1 1 
ATOM 5966 N ND2 . ASN D 4 169 ? 94.151  81.299  83.670  1.00 74.29  ? 169 ASN E ND2 1 
ATOM 5967 N N   . GLY D 4 170 ? 89.945  80.999  80.866  1.00 74.40  ? 170 GLY E N   1 
ATOM 5968 C CA  . GLY D 4 170 ? 89.706  81.036  79.440  1.00 73.57  ? 170 GLY E CA  1 
ATOM 5969 C C   . GLY D 4 170 ? 90.851  80.522  78.594  1.00 69.69  ? 170 GLY E C   1 
ATOM 5970 O O   . GLY D 4 170 ? 90.647  80.246  77.405  1.00 65.11  ? 170 GLY E O   1 
ATOM 5971 N N   . ASN D 4 171 ? 92.042  80.384  79.170  1.00 74.48  ? 171 ASN E N   1 
ATOM 5972 C CA  . ASN D 4 171 ? 93.190  79.861  78.445  1.00 78.32  ? 171 ASN E CA  1 
ATOM 5973 C C   . ASN D 4 171 ? 93.121  78.343  78.346  1.00 78.36  ? 171 ASN E C   1 
ATOM 5974 O O   . ASN D 4 171 ? 92.655  77.665  79.266  1.00 83.25  ? 171 ASN E O   1 
ATOM 5975 C CB  . ASN D 4 171 ? 94.492  80.282  79.127  1.00 78.19  ? 171 ASN E CB  1 
ATOM 5976 C CG  . ASN D 4 171 ? 94.707  81.782  79.097  1.00 82.26  ? 171 ASN E CG  1 
ATOM 5977 O OD1 . ASN D 4 171 ? 94.700  82.443  80.135  1.00 85.36  ? 171 ASN E OD1 1 
ATOM 5978 N ND2 . ASN D 4 171 ? 94.900  82.327  77.902  1.00 79.54  ? 171 ASN E ND2 1 
ATOM 5979 N N   . THR D 4 172 ? 93.590  77.812  77.220  1.00 78.88  ? 172 THR E N   1 
ATOM 5980 C CA  . THR D 4 172 ? 93.786  76.378  77.039  1.00 80.25  ? 172 THR E CA  1 
ATOM 5981 C C   . THR D 4 172 ? 95.282  76.136  76.883  1.00 79.09  ? 172 THR E C   1 
ATOM 5982 O O   . THR D 4 172 ? 95.859  76.426  75.829  1.00 80.67  ? 172 THR E O   1 
ATOM 5983 C CB  . THR D 4 172 ? 93.012  75.861  75.829  1.00 87.48  ? 172 THR E CB  1 
ATOM 5984 O OG1 . THR D 4 172 ? 91.617  76.147  75.994  1.00 87.98  ? 172 THR E OG1 1 
ATOM 5985 C CG2 . THR D 4 172 ? 93.202  74.360  75.679  1.00 87.38  ? 172 THR E CG2 1 
ATOM 5986 N N   . TYR D 4 173 ? 95.903  75.602  77.935  1.00 68.34  ? 173 TYR E N   1 
ATOM 5987 C CA  . TYR D 4 173 ? 97.360  75.520  78.039  1.00 70.55  ? 173 TYR E CA  1 
ATOM 5988 C C   . TYR D 4 173 ? 97.881  74.284  77.302  1.00 77.97  ? 173 TYR E C   1 
ATOM 5989 O O   . TYR D 4 173 ? 98.315  73.294  77.893  1.00 79.99  ? 173 TYR E O   1 
ATOM 5990 C CB  . TYR D 4 173 ? 97.785  75.515  79.500  1.00 67.06  ? 173 TYR E CB  1 
ATOM 5991 C CG  . TYR D 4 173 ? 97.386  76.760  80.257  1.00 75.42  ? 173 TYR E CG  1 
ATOM 5992 C CD1 . TYR D 4 173 ? 96.158  76.847  80.896  1.00 76.36  ? 173 TYR E CD1 1 
ATOM 5993 C CD2 . TYR D 4 173 ? 98.240  77.850  80.331  1.00 77.56  ? 173 TYR E CD2 1 
ATOM 5994 C CE1 . TYR D 4 173 ? 95.792  77.987  81.587  1.00 76.53  ? 173 TYR E CE1 1 
ATOM 5995 C CE2 . TYR D 4 173 ? 97.884  78.992  81.019  1.00 70.75  ? 173 TYR E CE2 1 
ATOM 5996 C CZ  . TYR D 4 173 ? 96.660  79.056  81.645  1.00 70.41  ? 173 TYR E CZ  1 
ATOM 5997 O OH  . TYR D 4 173 ? 96.304  80.194  82.331  1.00 71.07  ? 173 TYR E OH  1 
ATOM 5998 N N   . LEU D 4 174 ? 97.825  74.356  75.975  1.00 86.92  ? 174 LEU E N   1 
ATOM 5999 C CA  . LEU D 4 174 ? 98.380  73.323  75.112  1.00 85.29  ? 174 LEU E CA  1 
ATOM 6000 C C   . LEU D 4 174 ? 99.426  73.948  74.200  1.00 85.92  ? 174 LEU E C   1 
ATOM 6001 O O   . LEU D 4 174 ? 99.190  75.011  73.618  1.00 88.33  ? 174 LEU E O   1 
ATOM 6002 C CB  . LEU D 4 174 ? 97.294  72.646  74.275  1.00 86.89  ? 174 LEU E CB  1 
ATOM 6003 C CG  . LEU D 4 174 ? 97.833  71.595  73.301  1.00 87.89  ? 174 LEU E CG  1 
ATOM 6004 C CD1 . LEU D 4 174 ? 97.759  70.200  73.907  1.00 84.74  ? 174 LEU E CD1 1 
ATOM 6005 C CD2 . LEU D 4 174 ? 97.107  71.658  71.970  1.00 90.83  ? 174 LEU E CD2 1 
ATOM 6006 N N   . TYR D 4 175 ? 100.575 73.290  74.080  1.00 80.59  ? 175 TYR E N   1 
ATOM 6007 C CA  . TYR D 4 175 ? 101.683 73.789  73.282  1.00 82.25  ? 175 TYR E CA  1 
ATOM 6008 C C   . TYR D 4 175 ? 102.053 72.761  72.220  1.00 86.96  ? 175 TYR E C   1 
ATOM 6009 O O   . TYR D 4 175 ? 101.926 71.553  72.434  1.00 93.01  ? 175 TYR E O   1 
ATOM 6010 C CB  . TYR D 4 175 ? 102.898 74.105  74.168  1.00 80.97  ? 175 TYR E CB  1 
ATOM 6011 C CG  . TYR D 4 175 ? 102.700 75.310  75.065  1.00 85.04  ? 175 TYR E CG  1 
ATOM 6012 C CD1 . TYR D 4 175 ? 101.838 75.258  76.151  1.00 86.81  ? 175 TYR E CD1 1 
ATOM 6013 C CD2 . TYR D 4 175 ? 103.381 76.496  74.831  1.00 83.67  ? 175 TYR E CD2 1 
ATOM 6014 C CE1 . TYR D 4 175 ? 101.651 76.354  76.970  1.00 85.06  ? 175 TYR E CE1 1 
ATOM 6015 C CE2 . TYR D 4 175 ? 103.202 77.597  75.650  1.00 78.42  ? 175 TYR E CE2 1 
ATOM 6016 C CZ  . TYR D 4 175 ? 102.336 77.520  76.717  1.00 80.08  ? 175 TYR E CZ  1 
ATOM 6017 O OH  . TYR D 4 175 ? 102.153 78.611  77.535  1.00 83.79  ? 175 TYR E OH  1 
ATOM 6018 N N   . TRP D 4 176 ? 102.511 73.252  71.071  1.00 82.90  ? 176 TRP E N   1 
ATOM 6019 C CA  . TRP D 4 176 ? 102.982 72.410  69.978  1.00 80.97  ? 176 TRP E CA  1 
ATOM 6020 C C   . TRP D 4 176 ? 104.427 72.755  69.656  1.00 76.73  ? 176 TRP E C   1 
ATOM 6021 O O   . TRP D 4 176 ? 104.776 73.934  69.531  1.00 86.70  ? 176 TRP E O   1 
ATOM 6022 C CB  . TRP D 4 176 ? 102.106 72.569  68.732  1.00 84.44  ? 176 TRP E CB  1 
ATOM 6023 C CG  . TRP D 4 176 ? 100.848 71.755  68.770  1.00 85.12  ? 176 TRP E CG  1 
ATOM 6024 C CD1 . TRP D 4 176 ? 99.578  72.210  68.978  1.00 85.89  ? 176 TRP E CD1 1 
ATOM 6025 C CD2 . TRP D 4 176 ? 100.740 70.339  68.582  1.00 82.56  ? 176 TRP E CD2 1 
ATOM 6026 N NE1 . TRP D 4 176 ? 98.688  71.164  68.937  1.00 85.25  ? 176 TRP E NE1 1 
ATOM 6027 C CE2 . TRP D 4 176 ? 99.376  70.005  68.694  1.00 85.60  ? 176 TRP E CE2 1 
ATOM 6028 C CE3 . TRP D 4 176 ? 101.665 69.321  68.331  1.00 82.80  ? 176 TRP E CE3 1 
ATOM 6029 C CZ2 . TRP D 4 176 ? 98.915  68.697  68.564  1.00 90.97  ? 176 TRP E CZ2 1 
ATOM 6030 C CZ3 . TRP D 4 176 ? 101.206 68.023  68.203  1.00 86.81  ? 176 TRP E CZ3 1 
ATOM 6031 C CH2 . TRP D 4 176 ? 99.843  67.722  68.320  1.00 92.37  ? 176 TRP E CH2 1 
ATOM 6032 N N   . PHE D 4 177 ? 105.262 71.728  69.525  1.00 61.91  ? 177 PHE E N   1 
ATOM 6033 C CA  . PHE D 4 177 ? 106.667 71.900  69.192  1.00 64.24  ? 177 PHE E CA  1 
ATOM 6034 C C   . PHE D 4 177 ? 107.012 71.047  67.978  1.00 71.64  ? 177 PHE E C   1 
ATOM 6035 O O   . PHE D 4 177 ? 106.405 70.000  67.742  1.00 81.27  ? 177 PHE E O   1 
ATOM 6036 C CB  . PHE D 4 177 ? 107.567 71.525  70.378  1.00 70.84  ? 177 PHE E CB  1 
ATOM 6037 C CG  . PHE D 4 177 ? 107.311 72.342  71.613  1.00 70.34  ? 177 PHE E CG  1 
ATOM 6038 C CD1 . PHE D 4 177 ? 106.369 71.937  72.544  1.00 67.02  ? 177 PHE E CD1 1 
ATOM 6039 C CD2 . PHE D 4 177 ? 108.008 73.516  71.841  1.00 71.09  ? 177 PHE E CD2 1 
ATOM 6040 C CE1 . PHE D 4 177 ? 106.129 72.685  73.678  1.00 63.80  ? 177 PHE E CE1 1 
ATOM 6041 C CE2 . PHE D 4 177 ? 107.769 74.268  72.974  1.00 64.61  ? 177 PHE E CE2 1 
ATOM 6042 C CZ  . PHE D 4 177 ? 106.830 73.851  73.894  1.00 64.95  ? 177 PHE E CZ  1 
ATOM 6043 N N   . LEU D 4 178 ? 107.995 71.510  67.208  1.00 78.71  ? 178 LEU E N   1 
ATOM 6044 C CA  . LEU D 4 178 ? 108.515 70.770  66.064  1.00 75.50  ? 178 LEU E CA  1 
ATOM 6045 C C   . LEU D 4 178 ? 110.019 70.616  66.227  1.00 81.22  ? 178 LEU E C   1 
ATOM 6046 O O   . LEU D 4 178 ? 110.733 71.612  66.384  1.00 85.49  ? 178 LEU E O   1 
ATOM 6047 C CB  . LEU D 4 178 ? 108.187 71.479  64.747  1.00 74.80  ? 178 LEU E CB  1 
ATOM 6048 C CG  . LEU D 4 178 ? 108.895 70.970  63.490  1.00 78.70  ? 178 LEU E CG  1 
ATOM 6049 C CD1 . LEU D 4 178 ? 108.517 69.525  63.210  1.00 84.69  ? 178 LEU E CD1 1 
ATOM 6050 C CD2 . LEU D 4 178 ? 108.565 71.854  62.298  1.00 82.15  ? 178 LEU E CD2 1 
ATOM 6051 N N   . GLN D 4 179 ? 110.494 69.375  66.192  1.00 93.78  ? 179 GLN E N   1 
ATOM 6052 C CA  . GLN D 4 179 ? 111.920 69.062  66.255  1.00 95.93  ? 179 GLN E CA  1 
ATOM 6053 C C   . GLN D 4 179 ? 112.336 68.435  64.928  1.00 98.39  ? 179 GLN E C   1 
ATOM 6054 O O   . GLN D 4 179 ? 112.132 67.238  64.707  1.00 98.48  ? 179 GLN E O   1 
ATOM 6055 C CB  . GLN D 4 179 ? 112.222 68.135  67.428  1.00 95.38  ? 179 GLN E CB  1 
ATOM 6056 C CG  . GLN D 4 179 ? 113.702 67.870  67.640  1.00 93.86  ? 179 GLN E CG  1 
ATOM 6057 C CD  . GLN D 4 179 ? 113.968 66.988  68.844  1.00 96.49  ? 179 GLN E CD  1 
ATOM 6058 O OE1 . GLN D 4 179 ? 113.080 66.277  69.314  1.00 99.40  ? 179 GLN E OE1 1 
ATOM 6059 N NE2 . GLN D 4 179 ? 115.195 67.029  69.348  1.00 95.39  ? 179 GLN E NE2 1 
ATOM 6060 N N   . ARG D 4 180 ? 112.916 69.245  64.045  1.00 116.49 ? 180 ARG E N   1 
ATOM 6061 C CA  . ARG D 4 180 ? 113.434 68.718  62.795  1.00 117.20 ? 180 ARG E CA  1 
ATOM 6062 C C   . ARG D 4 180 ? 114.658 67.842  63.064  1.00 118.54 ? 180 ARG E C   1 
ATOM 6063 O O   . ARG D 4 180 ? 115.354 68.030  64.065  1.00 118.84 ? 180 ARG E O   1 
ATOM 6064 C CB  . ARG D 4 180 ? 113.809 69.857  61.849  1.00 115.73 ? 180 ARG E CB  1 
ATOM 6065 C CG  . ARG D 4 180 ? 112.674 70.820  61.541  1.00 115.88 ? 180 ARG E CG  1 
ATOM 6066 C CD  . ARG D 4 180 ? 113.115 71.873  60.537  1.00 117.07 ? 180 ARG E CD  1 
ATOM 6067 N NE  . ARG D 4 180 ? 112.088 72.883  60.309  1.00 118.07 ? 180 ARG E NE  1 
ATOM 6068 C CZ  . ARG D 4 180 ? 112.005 74.027  60.974  1.00 117.06 ? 180 ARG E CZ  1 
ATOM 6069 N NH1 . ARG D 4 180 ? 112.878 74.345  61.915  1.00 115.05 ? 180 ARG E NH1 1 
ATOM 6070 N NH2 . ARG D 4 180 ? 111.021 74.875  60.684  1.00 115.80 ? 180 ARG E NH2 1 
ATOM 6071 N N   . PRO D 4 181 ? 114.931 66.867  62.195  1.00 117.37 ? 181 PRO E N   1 
ATOM 6072 C CA  . PRO D 4 181 ? 116.064 65.957  62.432  1.00 118.50 ? 181 PRO E CA  1 
ATOM 6073 C C   . PRO D 4 181 ? 117.380 66.718  62.500  1.00 117.49 ? 181 PRO E C   1 
ATOM 6074 O O   . PRO D 4 181 ? 117.751 67.440  61.572  1.00 115.44 ? 181 PRO E O   1 
ATOM 6075 C CB  . PRO D 4 181 ? 116.015 65.009  61.227  1.00 116.16 ? 181 PRO E CB  1 
ATOM 6076 C CG  . PRO D 4 181 ? 115.197 65.727  60.197  1.00 114.58 ? 181 PRO E CG  1 
ATOM 6077 C CD  . PRO D 4 181 ? 114.190 66.511  60.974  1.00 113.13 ? 181 PRO E CD  1 
ATOM 6078 N N   . GLY D 4 182 ? 118.085 66.553  63.617  1.00 113.99 ? 182 GLY E N   1 
ATOM 6079 C CA  . GLY D 4 182 ? 119.342 67.233  63.836  1.00 113.76 ? 182 GLY E CA  1 
ATOM 6080 C C   . GLY D 4 182 ? 119.220 68.615  64.437  1.00 114.20 ? 182 GLY E C   1 
ATOM 6081 O O   . GLY D 4 182 ? 120.249 69.244  64.716  1.00 115.50 ? 182 GLY E O   1 
ATOM 6082 N N   . GLN D 4 183 ? 118.002 69.105  64.649  1.00 109.06 ? 183 GLN E N   1 
ATOM 6083 C CA  . GLN D 4 183 ? 117.763 70.454  65.133  1.00 108.32 ? 183 GLN E CA  1 
ATOM 6084 C C   . GLN D 4 183 ? 117.079 70.404  66.492  1.00 111.01 ? 183 GLN E C   1 
ATOM 6085 O O   . GLN D 4 183 ? 116.512 69.384  66.892  1.00 108.70 ? 183 GLN E O   1 
ATOM 6086 C CB  . GLN D 4 183 ? 116.912 71.263  64.146  1.00 107.53 ? 183 GLN E CB  1 
ATOM 6087 C CG  . GLN D 4 183 ? 117.605 71.560  62.828  1.00 110.81 ? 183 GLN E CG  1 
ATOM 6088 C CD  . GLN D 4 183 ? 116.812 72.515  61.959  1.00 112.81 ? 183 GLN E CD  1 
ATOM 6089 O OE1 . GLN D 4 183 ? 117.258 72.906  60.880  1.00 111.43 ? 183 GLN E OE1 1 
ATOM 6090 N NE2 . GLN D 4 183 ? 115.632 72.900  62.428  1.00 112.99 ? 183 GLN E NE2 1 
ATOM 6091 N N   . SER D 4 184 ? 117.143 71.525  67.198  1.00 104.68 ? 184 SER E N   1 
ATOM 6092 C CA  . SER D 4 184 ? 116.454 71.677  68.466  1.00 102.93 ? 184 SER E CA  1 
ATOM 6093 C C   . SER D 4 184 ? 114.957 71.879  68.254  1.00 100.14 ? 184 SER E C   1 
ATOM 6094 O O   . SER D 4 184 ? 114.521 72.301  67.180  1.00 102.51 ? 184 SER E O   1 
ATOM 6095 C CB  . SER D 4 184 ? 117.034 72.863  69.226  1.00 99.48  ? 184 SER E CB  1 
ATOM 6096 O OG  . SER D 4 184 ? 118.446 72.793  69.257  1.00 99.18  ? 184 SER E OG  1 
ATOM 6097 N N   . PRO D 4 185 ? 114.143 71.568  69.264  1.00 76.67  ? 185 PRO E N   1 
ATOM 6098 C CA  . PRO D 4 185 ? 112.702 71.812  69.145  1.00 73.57  ? 185 PRO E CA  1 
ATOM 6099 C C   . PRO D 4 185 ? 112.412 73.295  68.972  1.00 77.63  ? 185 PRO E C   1 
ATOM 6100 O O   . PRO D 4 185 ? 113.127 74.156  69.489  1.00 77.20  ? 185 PRO E O   1 
ATOM 6101 C CB  . PRO D 4 185 ? 112.140 71.280  70.469  1.00 72.62  ? 185 PRO E CB  1 
ATOM 6102 C CG  . PRO D 4 185 ? 113.149 70.282  70.927  1.00 80.59  ? 185 PRO E CG  1 
ATOM 6103 C CD  . PRO D 4 185 ? 114.477 70.823  70.490  1.00 79.29  ? 185 PRO E CD  1 
ATOM 6104 N N   . GLN D 4 186 ? 111.346 73.588  68.233  1.00 76.82  ? 186 GLN E N   1 
ATOM 6105 C CA  . GLN D 4 186 ? 110.899 74.957  68.027  1.00 74.90  ? 186 GLN E CA  1 
ATOM 6106 C C   . GLN D 4 186 ? 109.423 75.076  68.368  1.00 70.08  ? 186 GLN E C   1 
ATOM 6107 O O   . GLN D 4 186 ? 108.632 74.178  68.065  1.00 75.44  ? 186 GLN E O   1 
ATOM 6108 C CB  . GLN D 4 186 ? 111.130 75.394  66.575  1.00 72.27  ? 186 GLN E CB  1 
ATOM 6109 C CG  . GLN D 4 186 ? 111.022 76.886  66.336  1.00 78.41  ? 186 GLN E CG  1 
ATOM 6110 C CD  . GLN D 4 186 ? 111.493 77.281  64.951  1.00 77.57  ? 186 GLN E CD  1 
ATOM 6111 O OE1 . GLN D 4 186 ? 111.832 76.427  64.132  1.00 72.33  ? 186 GLN E OE1 1 
ATOM 6112 N NE2 . GLN D 4 186 ? 111.516 78.581  64.681  1.00 77.51  ? 186 GLN E NE2 1 
ATOM 6113 N N   . LEU D 4 187 ? 109.057 76.193  68.990  1.00 51.40  ? 187 LEU E N   1 
ATOM 6114 C CA  . LEU D 4 187 ? 107.665 76.422  69.350  1.00 54.15  ? 187 LEU E CA  1 
ATOM 6115 C C   . LEU D 4 187 ? 106.868 76.783  68.105  1.00 61.03  ? 187 LEU E C   1 
ATOM 6116 O O   . LEU D 4 187 ? 107.281 77.642  67.322  1.00 70.73  ? 187 LEU E O   1 
ATOM 6117 C CB  . LEU D 4 187 ? 107.551 77.532  70.391  1.00 59.40  ? 187 LEU E CB  1 
ATOM 6118 C CG  . LEU D 4 187 ? 106.118 77.891  70.789  1.00 62.00  ? 187 LEU E CG  1 
ATOM 6119 C CD1 . LEU D 4 187 ? 105.428 76.695  71.419  1.00 68.68  ? 187 LEU E CD1 1 
ATOM 6120 C CD2 . LEU D 4 187 ? 106.085 79.087  71.725  1.00 64.21  ? 187 LEU E CD2 1 
ATOM 6121 N N   . LEU D 4 188 ? 105.728 76.122  67.917  1.00 80.05  ? 188 LEU E N   1 
ATOM 6122 C CA  . LEU D 4 188 ? 104.806 76.457  66.842  1.00 84.57  ? 188 LEU E CA  1 
ATOM 6123 C C   . LEU D 4 188 ? 103.566 77.172  67.362  1.00 81.17  ? 188 LEU E C   1 
ATOM 6124 O O   . LEU D 4 188 ? 103.254 78.281  66.917  1.00 87.45  ? 188 LEU E O   1 
ATOM 6125 C CB  . LEU D 4 188 ? 104.405 75.186  66.082  1.00 85.42  ? 188 LEU E CB  1 
ATOM 6126 C CG  . LEU D 4 188 ? 105.538 74.344  65.502  1.00 83.99  ? 188 LEU E CG  1 
ATOM 6127 C CD1 . LEU D 4 188 ? 104.968 73.098  64.856  1.00 81.66  ? 188 LEU E CD1 1 
ATOM 6128 C CD2 . LEU D 4 188 ? 106.343 75.149  64.498  1.00 82.33  ? 188 LEU E CD2 1 
ATOM 6129 N N   . ILE D 4 189 ? 102.848 76.562  68.300  1.00 83.03  ? 189 ILE E N   1 
ATOM 6130 C CA  . ILE D 4 189 ? 101.596 77.095  68.818  1.00 85.06  ? 189 ILE E CA  1 
ATOM 6131 C C   . ILE D 4 189 ? 101.687 77.129  70.336  1.00 88.85  ? 189 ILE E C   1 
ATOM 6132 O O   . ILE D 4 189 ? 102.037 76.122  70.961  1.00 94.06  ? 189 ILE E O   1 
ATOM 6133 C CB  . ILE D 4 189 ? 100.387 76.254  68.366  1.00 86.10  ? 189 ILE E CB  1 
ATOM 6134 C CG1 . ILE D 4 189 ? 100.310 76.200  66.839  1.00 90.58  ? 189 ILE E CG1 1 
ATOM 6135 C CG2 . ILE D 4 189 ? 99.105  76.828  68.933  1.00 86.22  ? 189 ILE E CG2 1 
ATOM 6136 C CD1 . ILE D 4 189 ? 100.112 77.550  66.188  1.00 89.04  ? 189 ILE E CD1 1 
ATOM 6137 N N   . TYR D 4 190 ? 101.375 78.280  70.929  1.00 81.27  ? 190 TYR E N   1 
ATOM 6138 C CA  . TYR D 4 190 ? 101.355 78.424  72.378  1.00 81.49  ? 190 TYR E CA  1 
ATOM 6139 C C   . TYR D 4 190 ? 99.948  78.789  72.830  1.00 83.45  ? 190 TYR E C   1 
ATOM 6140 O O   . TYR D 4 190 ? 99.275  79.613  72.204  1.00 83.72  ? 190 TYR E O   1 
ATOM 6141 C CB  . TYR D 4 190 ? 102.375 79.468  72.865  1.00 82.35  ? 190 TYR E CB  1 
ATOM 6142 C CG  . TYR D 4 190 ? 102.170 80.881  72.368  1.00 82.39  ? 190 TYR E CG  1 
ATOM 6143 C CD1 . TYR D 4 190 ? 102.617 81.270  71.114  1.00 82.40  ? 190 TYR E CD1 1 
ATOM 6144 C CD2 . TYR D 4 190 ? 101.557 81.836  73.169  1.00 82.24  ? 190 TYR E CD2 1 
ATOM 6145 C CE1 . TYR D 4 190 ? 102.442 82.565  70.663  1.00 82.41  ? 190 TYR E CE1 1 
ATOM 6146 C CE2 . TYR D 4 190 ? 101.379 83.133  72.727  1.00 78.63  ? 190 TYR E CE2 1 
ATOM 6147 C CZ  . TYR D 4 190 ? 101.825 83.492  71.474  1.00 79.20  ? 190 TYR E CZ  1 
ATOM 6148 O OH  . TYR D 4 190 ? 101.647 84.781  71.027  1.00 79.69  ? 190 TYR E OH  1 
ATOM 6149 N N   . ARG D 4 191 ? 99.518  78.159  73.925  1.00 83.53  ? 191 ARG E N   1 
ATOM 6150 C CA  . ARG D 4 191 ? 98.144  78.251  74.425  1.00 85.34  ? 191 ARG E CA  1 
ATOM 6151 C C   . ARG D 4 191 ? 97.137  77.844  73.350  1.00 91.14  ? 191 ARG E C   1 
ATOM 6152 O O   . ARG D 4 191 ? 96.079  78.459  73.192  1.00 92.16  ? 191 ARG E O   1 
ATOM 6153 C CB  . ARG D 4 191 ? 97.837  79.645  74.976  1.00 80.31  ? 191 ARG E CB  1 
ATOM 6154 C CG  . ARG D 4 191 ? 98.440  79.890  76.352  1.00 82.44  ? 191 ARG E CG  1 
ATOM 6155 C CD  . ARG D 4 191 ? 97.978  81.207  76.954  1.00 87.19  ? 191 ARG E CD  1 
ATOM 6156 N NE  . ARG D 4 191 ? 98.529  82.356  76.248  1.00 88.91  ? 191 ARG E NE  1 
ATOM 6157 C CZ  . ARG D 4 191 ? 99.694  82.921  76.535  1.00 86.17  ? 191 ARG E CZ  1 
ATOM 6158 N NH1 . ARG D 4 191 ? 100.464 82.461  77.508  1.00 77.97  ? 191 ARG E NH1 1 
ATOM 6159 N NH2 . ARG D 4 191 ? 100.097 83.973  75.828  1.00 86.34  ? 191 ARG E NH2 1 
ATOM 6160 N N   . MET D 4 192 ? 97.498  76.811  72.586  1.00 104.81 ? 192 MET E N   1 
ATOM 6161 C CA  . MET D 4 192 ? 96.598  75.998  71.771  1.00 104.27 ? 192 MET E CA  1 
ATOM 6162 C C   . MET D 4 192 ? 96.100  76.718  70.520  1.00 103.97 ? 192 MET E C   1 
ATOM 6163 O O   . MET D 4 192 ? 95.607  76.072  69.590  1.00 106.19 ? 192 MET E O   1 
ATOM 6164 C CB  . MET D 4 192 ? 95.414  75.526  72.626  1.00 99.95  ? 192 MET E CB  1 
ATOM 6165 C CG  . MET D 4 192 ? 94.580  74.404  72.022  1.00 102.89 ? 192 MET E CG  1 
ATOM 6166 S SD  . MET D 4 192 ? 93.167  74.977  71.058  1.00 115.54 ? 192 MET E SD  1 
ATOM 6167 C CE  . MET D 4 192 ? 92.353  76.046  72.241  1.00 105.30 ? 192 MET E CE  1 
ATOM 6168 N N   . SER D 4 193 ? 96.257  78.040  70.453  1.00 92.95  ? 193 SER E N   1 
ATOM 6169 C CA  . SER D 4 193 ? 95.815  78.768  69.266  1.00 92.02  ? 193 SER E CA  1 
ATOM 6170 C C   . SER D 4 193 ? 96.795  79.821  68.768  1.00 90.54  ? 193 SER E C   1 
ATOM 6171 O O   . SER D 4 193 ? 96.805  80.098  67.565  1.00 91.50  ? 193 SER E O   1 
ATOM 6172 C CB  . SER D 4 193 ? 94.460  79.439  69.528  1.00 90.54  ? 193 SER E CB  1 
ATOM 6173 O OG  . SER D 4 193 ? 94.541  80.336  70.621  1.00 94.70  ? 193 SER E OG  1 
ATOM 6174 N N   . ASN D 4 194 ? 97.610  80.417  69.631  1.00 87.88  ? 194 ASN E N   1 
ATOM 6175 C CA  . ASN D 4 194 ? 98.462  81.530  69.239  1.00 90.39  ? 194 ASN E CA  1 
ATOM 6176 C C   . ASN D 4 194 ? 99.694  81.035  68.492  1.00 91.44  ? 194 ASN E C   1 
ATOM 6177 O O   . ASN D 4 194 ? 100.259 79.988  68.819  1.00 90.70  ? 194 ASN E O   1 
ATOM 6178 C CB  . ASN D 4 194 ? 98.872  82.341  70.466  1.00 90.26  ? 194 ASN E CB  1 
ATOM 6179 C CG  . ASN D 4 194 ? 97.681  82.907  71.215  1.00 90.49  ? 194 ASN E CG  1 
ATOM 6180 O OD1 . ASN D 4 194 ? 97.219  84.010  70.924  1.00 92.92  ? 194 ASN E OD1 1 
ATOM 6181 N ND2 . ASN D 4 194 ? 97.178  82.153  72.186  1.00 89.58  ? 194 ASN E ND2 1 
ATOM 6182 N N   . LEU D 4 195 ? 100.110 81.798  67.484  1.00 88.41  ? 195 LEU E N   1 
ATOM 6183 C CA  . LEU D 4 195 ? 101.252 81.433  66.657  1.00 87.78  ? 195 LEU E CA  1 
ATOM 6184 C C   . LEU D 4 195 ? 102.518 82.102  67.180  1.00 86.24  ? 195 LEU E C   1 
ATOM 6185 O O   . LEU D 4 195 ? 102.549 83.320  67.380  1.00 86.64  ? 195 LEU E O   1 
ATOM 6186 C CB  . LEU D 4 195 ? 101.010 81.834  65.202  1.00 87.96  ? 195 LEU E CB  1 
ATOM 6187 C CG  . LEU D 4 195 ? 102.113 81.431  64.223  1.00 87.56  ? 195 LEU E CG  1 
ATOM 6188 C CD1 . LEU D 4 195 ? 102.165 79.920  64.077  1.00 87.45  ? 195 LEU E CD1 1 
ATOM 6189 C CD2 . LEU D 4 195 ? 101.903 82.101  62.878  1.00 87.01  ? 195 LEU E CD2 1 
ATOM 6190 N N   . ALA D 4 196 ? 103.557 81.299  67.396  1.00 86.42  ? 196 ALA E N   1 
ATOM 6191 C CA  . ALA D 4 196 ? 104.804 81.799  67.956  1.00 85.64  ? 196 ALA E CA  1 
ATOM 6192 C C   . ALA D 4 196 ? 105.546 82.685  66.960  1.00 86.72  ? 196 ALA E C   1 
ATOM 6193 O O   . ALA D 4 196 ? 105.398 82.554  65.742  1.00 91.81  ? 196 ALA E O   1 
ATOM 6194 C CB  . ALA D 4 196 ? 105.699 80.638  68.383  1.00 89.98  ? 196 ALA E CB  1 
ATOM 6195 N N   . SER D 4 197 ? 106.346 83.603  67.500  1.00 97.00  ? 197 SER E N   1 
ATOM 6196 C CA  . SER D 4 197 ? 107.124 84.520  66.676  1.00 101.35 ? 197 SER E CA  1 
ATOM 6197 C C   . SER D 4 197 ? 108.147 83.763  65.837  1.00 108.66 ? 197 SER E C   1 
ATOM 6198 O O   . SER D 4 197 ? 108.852 82.882  66.337  1.00 109.54 ? 197 SER E O   1 
ATOM 6199 C CB  . SER D 4 197 ? 107.825 85.553  67.558  1.00 104.81 ? 197 SER E CB  1 
ATOM 6200 O OG  . SER D 4 197 ? 108.607 86.442  66.780  1.00 102.34 ? 197 SER E OG  1 
ATOM 6201 N N   . GLY D 4 198 ? 108.224 84.112  64.554  1.00 105.64 ? 198 GLY E N   1 
ATOM 6202 C CA  . GLY D 4 198 ? 109.133 83.462  63.633  1.00 101.77 ? 198 GLY E CA  1 
ATOM 6203 C C   . GLY D 4 198 ? 108.611 82.190  63.009  1.00 100.12 ? 198 GLY E C   1 
ATOM 6204 O O   . GLY D 4 198 ? 109.365 81.508  62.306  1.00 97.67  ? 198 GLY E O   1 
ATOM 6205 N N   . VAL D 4 199 ? 107.353 81.851  63.241  1.00 100.61 ? 199 VAL E N   1 
ATOM 6206 C CA  . VAL D 4 199 ? 106.740 80.636  62.709  1.00 100.69 ? 199 VAL E CA  1 
ATOM 6207 C C   . VAL D 4 199 ? 105.818 81.036  61.563  1.00 104.25 ? 199 VAL E C   1 
ATOM 6208 O O   . VAL D 4 199 ? 105.052 81.998  61.712  1.00 104.42 ? 199 VAL E O   1 
ATOM 6209 C CB  . VAL D 4 199 ? 105.962 79.876  63.798  1.00 97.21  ? 199 VAL E CB  1 
ATOM 6210 C CG1 . VAL D 4 199 ? 105.447 78.549  63.262  1.00 95.92  ? 199 VAL E CG1 1 
ATOM 6211 C CG2 . VAL D 4 199 ? 106.842 79.665  65.011  1.00 97.08  ? 199 VAL E CG2 1 
ATOM 6212 N N   . PRO D 4 200 ? 105.869 80.353  60.418  1.00 109.57 ? 200 PRO E N   1 
ATOM 6213 C CA  . PRO D 4 200 ? 105.006 80.739  59.296  1.00 108.45 ? 200 PRO E CA  1 
ATOM 6214 C C   . PRO D 4 200 ? 103.532 80.622  59.657  1.00 108.45 ? 200 PRO E C   1 
ATOM 6215 O O   . PRO D 4 200 ? 103.129 79.781  60.463  1.00 109.79 ? 200 PRO E O   1 
ATOM 6216 C CB  . PRO D 4 200 ? 105.392 79.746  58.194  1.00 107.82 ? 200 PRO E CB  1 
ATOM 6217 C CG  . PRO D 4 200 ? 106.777 79.315  58.546  1.00 105.54 ? 200 PRO E CG  1 
ATOM 6218 C CD  . PRO D 4 200 ? 106.821 79.294  60.045  1.00 105.53 ? 200 PRO E CD  1 
ATOM 6219 N N   . ASP D 4 201 ? 102.725 81.491  59.043  1.00 107.40 ? 201 ASP E N   1 
ATOM 6220 C CA  . ASP D 4 201 ? 101.299 81.574  59.337  1.00 106.49 ? 201 ASP E CA  1 
ATOM 6221 C C   . ASP D 4 201 ? 100.514 80.350  58.881  1.00 110.07 ? 201 ASP E C   1 
ATOM 6222 O O   . ASP D 4 201 ? 99.345  80.216  59.257  1.00 112.62 ? 201 ASP E O   1 
ATOM 6223 C CB  . ASP D 4 201 ? 100.709 82.831  58.693  1.00 107.66 ? 201 ASP E CB  1 
ATOM 6224 C CG  . ASP D 4 201 ? 101.007 82.919  57.209  1.00 111.08 ? 201 ASP E CG  1 
ATOM 6225 O OD1 . ASP D 4 201 ? 102.086 82.452  56.789  1.00 112.14 ? 201 ASP E OD1 1 
ATOM 6226 O OD2 . ASP D 4 201 ? 100.163 83.458  56.462  1.00 110.43 ? 201 ASP E OD2 1 
ATOM 6227 N N   . ARG D 4 202 ? 101.116 79.467  58.082  1.00 108.03 ? 202 ARG E N   1 
ATOM 6228 C CA  . ARG D 4 202 ? 100.402 78.282  57.616  1.00 106.70 ? 202 ARG E CA  1 
ATOM 6229 C C   . ARG D 4 202 ? 100.040 77.342  58.761  1.00 108.05 ? 202 ARG E C   1 
ATOM 6230 O O   . ARG D 4 202 ? 99.030  76.633  58.681  1.00 109.50 ? 202 ARG E O   1 
ATOM 6231 C CB  . ARG D 4 202 ? 101.234 77.556  56.558  1.00 104.82 ? 202 ARG E CB  1 
ATOM 6232 C CG  . ARG D 4 202 ? 102.596 77.083  57.037  1.00 107.01 ? 202 ARG E CG  1 
ATOM 6233 C CD  . ARG D 4 202 ? 103.303 76.263  55.969  1.00 106.18 ? 202 ARG E CD  1 
ATOM 6234 N NE  . ARG D 4 202 ? 104.611 75.800  56.416  1.00 105.44 ? 202 ARG E NE  1 
ATOM 6235 C CZ  . ARG D 4 202 ? 105.743 76.462  56.221  1.00 108.39 ? 202 ARG E CZ  1 
ATOM 6236 N NH1 . ARG D 4 202 ? 105.766 77.618  55.580  1.00 107.18 ? 202 ARG E NH1 1 
ATOM 6237 N NH2 . ARG D 4 202 ? 106.881 75.951  56.682  1.00 110.66 ? 202 ARG E NH2 1 
ATOM 6238 N N   . PHE D 4 203 ? 100.839 77.318  59.825  1.00 104.08 ? 203 PHE E N   1 
ATOM 6239 C CA  . PHE D 4 203 ? 100.485 76.542  61.007  1.00 102.82 ? 203 PHE E CA  1 
ATOM 6240 C C   . PHE D 4 203 ? 99.322  77.191  61.751  1.00 102.87 ? 203 PHE E C   1 
ATOM 6241 O O   . PHE D 4 203 ? 99.312  78.406  61.971  1.00 106.37 ? 203 PHE E O   1 
ATOM 6242 C CB  . PHE D 4 203 ? 101.694 76.407  61.931  1.00 105.13 ? 203 PHE E CB  1 
ATOM 6243 C CG  . PHE D 4 203 ? 102.864 75.706  61.301  1.00 105.78 ? 203 PHE E CG  1 
ATOM 6244 C CD1 . PHE D 4 203 ? 102.917 74.323  61.252  1.00 105.97 ? 203 PHE E CD1 1 
ATOM 6245 C CD2 . PHE D 4 203 ? 103.914 76.430  60.760  1.00 104.57 ? 203 PHE E CD2 1 
ATOM 6246 C CE1 . PHE D 4 203 ? 103.993 73.675  60.674  1.00 104.15 ? 203 PHE E CE1 1 
ATOM 6247 C CE2 . PHE D 4 203 ? 104.993 75.788  60.181  1.00 106.78 ? 203 PHE E CE2 1 
ATOM 6248 C CZ  . PHE D 4 203 ? 105.032 74.409  60.138  1.00 108.09 ? 203 PHE E CZ  1 
ATOM 6249 N N   . SER D 4 204 ? 98.342  76.376  62.138  1.00 107.68 ? 204 SER E N   1 
ATOM 6250 C CA  . SER D 4 204 ? 97.191  76.834  62.904  1.00 108.81 ? 204 SER E CA  1 
ATOM 6251 C C   . SER D 4 204 ? 96.798  75.760  63.908  1.00 111.34 ? 204 SER E C   1 
ATOM 6252 O O   . SER D 4 204 ? 96.738  74.575  63.568  1.00 113.13 ? 204 SER E O   1 
ATOM 6253 C CB  . SER D 4 204 ? 96.002  77.163  61.992  1.00 109.83 ? 204 SER E CB  1 
ATOM 6254 O OG  . SER D 4 204 ? 95.597  76.027  61.248  1.00 115.31 ? 204 SER E OG  1 
ATOM 6255 N N   . GLY D 4 205 ? 96.515  76.182  65.138  1.00 106.02 ? 205 GLY E N   1 
ATOM 6256 C CA  . GLY D 4 205 ? 96.125  75.279  66.209  1.00 106.13 ? 205 GLY E CA  1 
ATOM 6257 C C   . GLY D 4 205 ? 94.653  75.421  66.561  1.00 106.55 ? 205 GLY E C   1 
ATOM 6258 O O   . GLY D 4 205 ? 94.173  76.524  66.834  1.00 108.97 ? 205 GLY E O   1 
ATOM 6259 N N   . SER D 4 206 ? 93.951  74.289  66.551  1.00 110.25 ? 206 SER E N   1 
ATOM 6260 C CA  . SER D 4 206 ? 92.538  74.219  66.897  1.00 111.29 ? 206 SER E CA  1 
ATOM 6261 C C   . SER D 4 206 ? 92.322  73.078  67.881  1.00 110.49 ? 206 SER E C   1 
ATOM 6262 O O   . SER D 4 206 ? 92.929  72.012  67.749  1.00 108.44 ? 206 SER E O   1 
ATOM 6263 C CB  . SER D 4 206 ? 91.665  74.014  65.652  1.00 113.43 ? 206 SER E CB  1 
ATOM 6264 O OG  . SER D 4 206 ? 92.007  72.814  64.980  1.00 114.64 ? 206 SER E OG  1 
ATOM 6265 N N   . GLY D 4 207 ? 91.454  73.298  68.863  1.00 113.75 ? 207 GLY E N   1 
ATOM 6266 C CA  . GLY D 4 207 ? 91.190  72.255  69.839  1.00 113.62 ? 207 GLY E CA  1 
ATOM 6267 C C   . GLY D 4 207 ? 89.961  72.566  70.662  1.00 114.24 ? 207 GLY E C   1 
ATOM 6268 O O   . GLY D 4 207 ? 89.385  73.655  70.581  1.00 114.96 ? 207 GLY E O   1 
ATOM 6269 N N   . SER D 4 208 ? 89.568  71.577  71.463  1.00 113.44 ? 208 SER E N   1 
ATOM 6270 C CA  . SER D 4 208 ? 88.486  71.740  72.425  1.00 113.69 ? 208 SER E CA  1 
ATOM 6271 C C   . SER D 4 208 ? 88.621  70.665  73.491  1.00 113.57 ? 208 SER E C   1 
ATOM 6272 O O   . SER D 4 208 ? 88.782  69.485  73.164  1.00 114.67 ? 208 SER E O   1 
ATOM 6273 C CB  . SER D 4 208 ? 87.117  71.647  71.741  1.00 115.19 ? 208 SER E CB  1 
ATOM 6274 O OG  . SER D 4 208 ? 86.067  71.804  72.679  1.00 114.12 ? 208 SER E OG  1 
ATOM 6275 N N   . GLY D 4 209 ? 88.547  71.074  74.756  1.00 110.81 ? 209 GLY E N   1 
ATOM 6276 C CA  . GLY D 4 209 ? 88.570  70.142  75.868  1.00 111.85 ? 209 GLY E CA  1 
ATOM 6277 C C   . GLY D 4 209 ? 89.837  69.315  75.936  1.00 113.46 ? 209 GLY E C   1 
ATOM 6278 O O   . GLY D 4 209 ? 90.892  69.818  76.331  1.00 113.88 ? 209 GLY E O   1 
ATOM 6279 N N   . THR D 4 210 ? 89.744  68.038  75.560  1.00 109.04 ? 210 THR E N   1 
ATOM 6280 C CA  . THR D 4 210 ? 90.879  67.128  75.608  1.00 106.64 ? 210 THR E CA  1 
ATOM 6281 C C   . THR D 4 210 ? 91.405  66.745  74.232  1.00 103.62 ? 210 THR E C   1 
ATOM 6282 O O   . THR D 4 210 ? 92.441  66.077  74.150  1.00 105.87 ? 210 THR E O   1 
ATOM 6283 C CB  . THR D 4 210 ? 90.510  65.850  76.377  1.00 107.00 ? 210 THR E CB  1 
ATOM 6284 O OG1 . THR D 4 210 ? 89.400  65.207  75.738  1.00 107.68 ? 210 THR E OG1 1 
ATOM 6285 C CG2 . THR D 4 210 ? 90.138  66.182  77.814  1.00 105.47 ? 210 THR E CG2 1 
ATOM 6286 N N   . ALA D 4 211 ? 90.730  67.146  73.159  1.00 100.89 ? 211 ALA E N   1 
ATOM 6287 C CA  . ALA D 4 211 ? 91.108  66.788  71.800  1.00 103.50 ? 211 ALA E CA  1 
ATOM 6288 C C   . ALA D 4 211 ? 91.535  68.042  71.050  1.00 107.62 ? 211 ALA E C   1 
ATOM 6289 O O   . ALA D 4 211 ? 90.807  69.040  71.037  1.00 109.21 ? 211 ALA E O   1 
ATOM 6290 C CB  . ALA D 4 211 ? 89.953  66.099  71.070  1.00 104.10 ? 211 ALA E CB  1 
ATOM 6291 N N   . PHE D 4 212 ? 92.710  67.986  70.429  1.00 109.12 ? 212 PHE E N   1 
ATOM 6292 C CA  . PHE D 4 212 ? 93.299  69.136  69.761  1.00 106.71 ? 212 PHE E CA  1 
ATOM 6293 C C   . PHE D 4 212 ? 93.818  68.725  68.391  1.00 108.60 ? 212 PHE E C   1 
ATOM 6294 O O   . PHE D 4 212 ? 94.244  67.585  68.187  1.00 111.11 ? 212 PHE E O   1 
ATOM 6295 C CB  . PHE D 4 212 ? 94.440  69.738  70.584  1.00 106.00 ? 212 PHE E CB  1 
ATOM 6296 C CG  . PHE D 4 212 ? 94.093  69.969  72.026  1.00 107.49 ? 212 PHE E CG  1 
ATOM 6297 C CD1 . PHE D 4 212 ? 93.423  71.116  72.416  1.00 107.85 ? 212 PHE E CD1 1 
ATOM 6298 C CD2 . PHE D 4 212 ? 94.447  69.044  72.993  1.00 106.88 ? 212 PHE E CD2 1 
ATOM 6299 C CE1 . PHE D 4 212 ? 93.106  71.332  73.743  1.00 106.76 ? 212 PHE E CE1 1 
ATOM 6300 C CE2 . PHE D 4 212 ? 94.134  69.255  74.321  1.00 108.56 ? 212 PHE E CE2 1 
ATOM 6301 C CZ  . PHE D 4 212 ? 93.463  70.401  74.697  1.00 108.29 ? 212 PHE E CZ  1 
ATOM 6302 N N   . THR D 4 213 ? 93.780  69.668  67.452  1.00 116.32 ? 213 THR E N   1 
ATOM 6303 C CA  . THR D 4 213 ? 94.215  69.423  66.084  1.00 119.85 ? 213 THR E CA  1 
ATOM 6304 C C   . THR D 4 213 ? 95.130  70.552  65.634  1.00 117.52 ? 213 THR E C   1 
ATOM 6305 O O   . THR D 4 213 ? 94.820  71.729  65.838  1.00 117.59 ? 213 THR E O   1 
ATOM 6306 C CB  . THR D 4 213 ? 93.014  69.305  65.137  1.00 118.29 ? 213 THR E CB  1 
ATOM 6307 O OG1 . THR D 4 213 ? 92.127  68.285  65.613  1.00 117.55 ? 213 THR E OG1 1 
ATOM 6308 C CG2 . THR D 4 213 ? 93.472  68.952  63.731  1.00 115.88 ? 213 THR E CG2 1 
ATOM 6309 N N   . LEU D 4 214 ? 96.250  70.189  65.017  1.00 104.59 ? 214 LEU E N   1 
ATOM 6310 C CA  . LEU D 4 214 ? 97.171  71.138  64.404  1.00 103.21 ? 214 LEU E CA  1 
ATOM 6311 C C   . LEU D 4 214 ? 97.064  71.015  62.891  1.00 108.05 ? 214 LEU E C   1 
ATOM 6312 O O   . LEU D 4 214 ? 97.393  69.965  62.327  1.00 111.85 ? 214 LEU E O   1 
ATOM 6313 C CB  . LEU D 4 214 ? 98.605  70.887  64.870  1.00 102.37 ? 214 LEU E CB  1 
ATOM 6314 C CG  . LEU D 4 214 ? 99.709  71.714  64.206  1.00 101.43 ? 214 LEU E CG  1 
ATOM 6315 C CD1 . LEU D 4 214 ? 99.498  73.198  64.455  1.00 102.69 ? 214 LEU E CD1 1 
ATOM 6316 C CD2 . LEU D 4 214 ? 101.079 71.277  64.700  1.00 100.89 ? 214 LEU E CD2 1 
ATOM 6317 N N   . THR D 4 215 ? 96.609  72.079  62.237  1.00 111.55 ? 215 THR E N   1 
ATOM 6318 C CA  . THR D 4 215 ? 96.413  72.081  60.794  1.00 111.67 ? 215 THR E CA  1 
ATOM 6319 C C   . THR D 4 215 ? 97.575  72.808  60.130  1.00 107.54 ? 215 THR E C   1 
ATOM 6320 O O   . THR D 4 215 ? 97.907  73.936  60.508  1.00 106.83 ? 215 THR E O   1 
ATOM 6321 C CB  . THR D 4 215 ? 95.089  72.753  60.422  1.00 110.31 ? 215 THR E CB  1 
ATOM 6322 O OG1 . THR D 4 215 ? 94.008  72.075  61.074  1.00 109.05 ? 215 THR E OG1 1 
ATOM 6323 C CG2 . THR D 4 215 ? 94.872  72.709  58.917  1.00 110.41 ? 215 THR E CG2 1 
ATOM 6324 N N   . ILE D 4 216 ? 98.188  72.157  59.146  1.00 109.23 ? 216 ILE E N   1 
ATOM 6325 C CA  . ILE D 4 216 ? 99.330  72.698  58.416  1.00 110.94 ? 216 ILE E CA  1 
ATOM 6326 C C   . ILE D 4 216 ? 98.922  72.808  56.953  1.00 113.07 ? 216 ILE E C   1 
ATOM 6327 O O   . ILE D 4 216 ? 98.966  71.819  56.211  1.00 115.61 ? 216 ILE E O   1 
ATOM 6328 C CB  . ILE D 4 216 ? 100.584 71.833  58.580  1.00 112.76 ? 216 ILE E CB  1 
ATOM 6329 C CG1 . ILE D 4 216 ? 100.880 71.600  60.063  1.00 110.07 ? 216 ILE E CG1 1 
ATOM 6330 C CG2 . ILE D 4 216 ? 101.773 72.486  57.894  1.00 111.65 ? 216 ILE E CG2 1 
ATOM 6331 C CD1 . ILE D 4 216 ? 102.052 70.676  60.314  1.00 111.36 ? 216 ILE E CD1 1 
ATOM 6332 N N   . SER D 4 217 ? 98.523  74.003  56.528  1.00 112.96 ? 217 SER E N   1 
ATOM 6333 C CA  . SER D 4 217 ? 98.145  74.215  55.139  1.00 114.40 ? 217 SER E CA  1 
ATOM 6334 C C   . SER D 4 217 ? 99.387  74.430  54.284  1.00 114.76 ? 217 SER E C   1 
ATOM 6335 O O   . SER D 4 217 ? 100.322 75.128  54.686  1.00 116.86 ? 217 SER E O   1 
ATOM 6336 C CB  . SER D 4 217 ? 97.209  75.417  55.016  1.00 114.00 ? 217 SER E CB  1 
ATOM 6337 O OG  . SER D 4 217 ? 96.022  75.216  55.764  1.00 113.55 ? 217 SER E OG  1 
ATOM 6338 N N   . ARG D 4 218 ? 99.386  73.825  53.095  1.00 109.10 ? 218 ARG E N   1 
ATOM 6339 C CA  . ARG D 4 218 ? 100.481 73.944  52.131  1.00 109.32 ? 218 ARG E CA  1 
ATOM 6340 C C   . ARG D 4 218 ? 101.813 73.519  52.755  1.00 112.31 ? 218 ARG E C   1 
ATOM 6341 O O   . ARG D 4 218 ? 102.740 74.316  52.916  1.00 113.40 ? 218 ARG E O   1 
ATOM 6342 C CB  . ARG D 4 218 ? 100.564 75.365  51.561  1.00 110.43 ? 218 ARG E CB  1 
ATOM 6343 C CG  . ARG D 4 218 ? 99.309  75.823  50.834  1.00 110.48 ? 218 ARG E CG  1 
ATOM 6344 C CD  . ARG D 4 218 ? 98.467  76.736  51.710  1.00 112.59 ? 218 ARG E CD  1 
ATOM 6345 N NE  . ARG D 4 218 ? 99.177  77.964  52.046  1.00 112.86 ? 218 ARG E NE  1 
ATOM 6346 C CZ  . ARG D 4 218 ? 98.670  78.950  52.772  1.00 112.14 ? 218 ARG E CZ  1 
ATOM 6347 N NH1 . ARG D 4 218 ? 97.441  78.888  53.259  1.00 111.68 ? 218 ARG E NH1 1 
ATOM 6348 N NH2 . ARG D 4 218 ? 99.413  80.025  53.016  1.00 111.53 ? 218 ARG E NH2 1 
ATOM 6349 N N   . LEU D 4 219 ? 101.881 72.240  53.121  1.00 112.39 ? 219 LEU E N   1 
ATOM 6350 C CA  . LEU D 4 219 ? 103.069 71.700  53.770  1.00 112.59 ? 219 LEU E CA  1 
ATOM 6351 C C   . LEU D 4 219 ? 104.289 71.866  52.872  1.00 112.41 ? 219 LEU E C   1 
ATOM 6352 O O   . LEU D 4 219 ? 104.202 71.749  51.647  1.00 113.49 ? 219 LEU E O   1 
ATOM 6353 C CB  . LEU D 4 219 ? 102.860 70.225  54.120  1.00 110.02 ? 219 LEU E CB  1 
ATOM 6354 C CG  . LEU D 4 219 ? 104.000 69.504  54.845  1.00 111.11 ? 219 LEU E CG  1 
ATOM 6355 C CD1 . LEU D 4 219 ? 103.461 68.655  55.982  1.00 111.23 ? 219 LEU E CD1 1 
ATOM 6356 C CD2 . LEU D 4 219 ? 104.804 68.647  53.877  1.00 112.41 ? 219 LEU E CD2 1 
ATOM 6357 N N   . GLU D 4 220 ? 105.431 72.143  53.489  1.00 105.01 ? 220 GLU E N   1 
ATOM 6358 C CA  . GLU D 4 220 ? 106.690 72.344  52.786  1.00 105.72 ? 220 GLU E CA  1 
ATOM 6359 C C   . GLU D 4 220 ? 107.739 71.369  53.313  1.00 107.56 ? 220 GLU E C   1 
ATOM 6360 O O   . GLU D 4 220 ? 107.500 70.608  54.253  1.00 108.34 ? 220 GLU E O   1 
ATOM 6361 C CB  . GLU D 4 220 ? 107.167 73.793  52.928  1.00 106.29 ? 220 GLU E CB  1 
ATOM 6362 C CG  . GLU D 4 220 ? 106.187 74.823  52.392  1.00 106.56 ? 220 GLU E CG  1 
ATOM 6363 C CD  . GLU D 4 220 ? 106.715 76.240  52.496  1.00 108.51 ? 220 GLU E CD  1 
ATOM 6364 O OE1 . GLU D 4 220 ? 107.903 76.409  52.841  1.00 108.26 ? 220 GLU E OE1 1 
ATOM 6365 O OE2 . GLU D 4 220 ? 105.942 77.184  52.231  1.00 108.42 ? 220 GLU E OE2 1 
ATOM 6366 N N   . ALA D 4 221 ? 108.916 71.399  52.681  1.00 110.83 ? 221 ALA E N   1 
ATOM 6367 C CA  . ALA D 4 221 ? 109.992 70.492  53.067  1.00 110.39 ? 221 ALA E CA  1 
ATOM 6368 C C   . ALA D 4 221 ? 110.469 70.769  54.487  1.00 112.37 ? 221 ALA E C   1 
ATOM 6369 O O   . ALA D 4 221 ? 110.819 69.841  55.225  1.00 112.21 ? 221 ALA E O   1 
ATOM 6370 C CB  . ALA D 4 221 ? 111.152 70.603  52.079  1.00 108.48 ? 221 ALA E CB  1 
ATOM 6371 N N   . GLU D 4 222 ? 110.504 72.044  54.884  1.00 113.80 ? 222 GLU E N   1 
ATOM 6372 C CA  . GLU D 4 222 ? 110.986 72.388  56.217  1.00 112.51 ? 222 GLU E CA  1 
ATOM 6373 C C   . GLU D 4 222 ? 110.069 71.843  57.305  1.00 112.40 ? 222 GLU E C   1 
ATOM 6374 O O   . GLU D 4 222 ? 110.534 71.535  58.408  1.00 112.24 ? 222 GLU E O   1 
ATOM 6375 C CB  . GLU D 4 222 ? 111.130 73.904  56.350  1.00 112.43 ? 222 GLU E CB  1 
ATOM 6376 C CG  . GLU D 4 222 ? 109.867 74.683  56.025  1.00 115.24 ? 222 GLU E CG  1 
ATOM 6377 C CD  . GLU D 4 222 ? 110.061 76.182  56.140  1.00 116.06 ? 222 GLU E CD  1 
ATOM 6378 O OE1 . GLU D 4 222 ? 111.191 76.614  56.450  1.00 118.51 ? 222 GLU E OE1 1 
ATOM 6379 O OE2 . GLU D 4 222 ? 109.083 76.927  55.923  1.00 115.40 ? 222 GLU E OE2 1 
ATOM 6380 N N   . ASP D 4 223 ? 108.771 71.718  57.018  1.00 108.88 ? 223 ASP E N   1 
ATOM 6381 C CA  . ASP D 4 223 ? 107.813 71.236  58.006  1.00 109.80 ? 223 ASP E CA  1 
ATOM 6382 C C   . ASP D 4 223 ? 108.014 69.769  58.362  1.00 110.77 ? 223 ASP E C   1 
ATOM 6383 O O   . ASP D 4 223 ? 107.445 69.311  59.359  1.00 110.44 ? 223 ASP E O   1 
ATOM 6384 C CB  . ASP D 4 223 ? 106.386 71.449  57.497  1.00 110.02 ? 223 ASP E CB  1 
ATOM 6385 C CG  . ASP D 4 223 ? 106.066 72.910  57.255  1.00 108.57 ? 223 ASP E CG  1 
ATOM 6386 O OD1 . ASP D 4 223 ? 106.954 73.757  57.484  1.00 109.69 ? 223 ASP E OD1 1 
ATOM 6387 O OD2 . ASP D 4 223 ? 104.929 73.211  56.837  1.00 104.96 ? 223 ASP E OD2 1 
ATOM 6388 N N   . VAL D 4 224 ? 108.789 69.023  57.570  1.00 119.36 ? 224 VAL E N   1 
ATOM 6389 C CA  . VAL D 4 224 ? 109.041 67.619  57.869  1.00 121.39 ? 224 VAL E CA  1 
ATOM 6390 C C   . VAL D 4 224 ? 109.744 67.497  59.212  1.00 121.43 ? 224 VAL E C   1 
ATOM 6391 O O   . VAL D 4 224 ? 110.759 68.159  59.465  1.00 121.24 ? 224 VAL E O   1 
ATOM 6392 C CB  . VAL D 4 224 ? 109.863 66.973  56.743  1.00 119.88 ? 224 VAL E CB  1 
ATOM 6393 C CG1 . VAL D 4 224 ? 110.219 65.538  57.100  1.00 117.66 ? 224 VAL E CG1 1 
ATOM 6394 C CG2 . VAL D 4 224 ? 109.095 67.025  55.431  1.00 118.06 ? 224 VAL E CG2 1 
ATOM 6395 N N   . GLY D 4 225 ? 109.207 66.653  60.080  1.00 106.33 ? 225 GLY E N   1 
ATOM 6396 C CA  . GLY D 4 225 ? 109.798 66.437  61.383  1.00 104.82 ? 225 GLY E CA  1 
ATOM 6397 C C   . GLY D 4 225 ? 108.805 65.777  62.320  1.00 106.12 ? 225 GLY E C   1 
ATOM 6398 O O   . GLY D 4 225 ? 107.731 65.339  61.912  1.00 108.20 ? 225 GLY E O   1 
ATOM 6399 N N   . VAL D 4 226 ? 109.197 65.719  63.591  1.00 97.88  ? 226 VAL E N   1 
ATOM 6400 C CA  . VAL D 4 226 ? 108.366 65.163  64.653  1.00 96.88  ? 226 VAL E CA  1 
ATOM 6401 C C   . VAL D 4 226 ? 107.687 66.303  65.396  1.00 95.24  ? 226 VAL E C   1 
ATOM 6402 O O   . VAL D 4 226 ? 108.319 67.318  65.714  1.00 97.50  ? 226 VAL E O   1 
ATOM 6403 C CB  . VAL D 4 226 ? 109.199 64.291  65.613  1.00 93.76  ? 226 VAL E CB  1 
ATOM 6404 C CG1 . VAL D 4 226 ? 108.291 63.573  66.601  1.00 93.32  ? 226 VAL E CG1 1 
ATOM 6405 C CG2 . VAL D 4 226 ? 110.040 63.295  64.830  1.00 93.23  ? 226 VAL E CG2 1 
ATOM 6406 N N   . TYR D 4 227 ? 106.397 66.137  65.676  1.00 87.75  ? 227 TYR E N   1 
ATOM 6407 C CA  . TYR D 4 227 ? 105.599 67.141  66.366  1.00 84.28  ? 227 TYR E CA  1 
ATOM 6408 C C   . TYR D 4 227 ? 105.204 66.627  67.744  1.00 90.59  ? 227 TYR E C   1 
ATOM 6409 O O   . TYR D 4 227 ? 104.670 65.519  67.868  1.00 97.27  ? 227 TYR E O   1 
ATOM 6410 C CB  . TYR D 4 227 ? 104.345 67.488  65.559  1.00 81.42  ? 227 TYR E CB  1 
ATOM 6411 C CG  . TYR D 4 227 ? 104.619 68.206  64.256  1.00 84.64  ? 227 TYR E CG  1 
ATOM 6412 C CD1 . TYR D 4 227 ? 105.145 67.531  63.163  1.00 88.82  ? 227 TYR E CD1 1 
ATOM 6413 C CD2 . TYR D 4 227 ? 104.338 69.558  64.115  1.00 91.56  ? 227 TYR E CD2 1 
ATOM 6414 C CE1 . TYR D 4 227 ? 105.392 68.185  61.971  1.00 91.77  ? 227 TYR E CE1 1 
ATOM 6415 C CE2 . TYR D 4 227 ? 104.580 70.218  62.925  1.00 93.27  ? 227 TYR E CE2 1 
ATOM 6416 C CZ  . TYR D 4 227 ? 105.108 69.528  61.858  1.00 93.55  ? 227 TYR E CZ  1 
ATOM 6417 O OH  . TYR D 4 227 ? 105.352 70.184  60.673  1.00 90.96  ? 227 TYR E OH  1 
ATOM 6418 N N   . TYR D 4 228 ? 105.469 67.429  68.773  1.00 82.63  ? 228 TYR E N   1 
ATOM 6419 C CA  . TYR D 4 228 ? 105.152 67.079  70.150  1.00 80.40  ? 228 TYR E CA  1 
ATOM 6420 C C   . TYR D 4 228 ? 104.134 68.066  70.703  1.00 78.76  ? 228 TYR E C   1 
ATOM 6421 O O   . TYR D 4 228 ? 104.260 69.276  70.496  1.00 82.52  ? 228 TYR E O   1 
ATOM 6422 C CB  . TYR D 4 228 ? 106.410 67.089  71.025  1.00 81.67  ? 228 TYR E CB  1 
ATOM 6423 C CG  . TYR D 4 228 ? 107.442 66.058  70.632  1.00 85.40  ? 228 TYR E CG  1 
ATOM 6424 C CD1 . TYR D 4 228 ? 107.369 64.756  71.105  1.00 88.51  ? 228 TYR E CD1 1 
ATOM 6425 C CD2 . TYR D 4 228 ? 108.494 66.390  69.789  1.00 84.71  ? 228 TYR E CD2 1 
ATOM 6426 C CE1 . TYR D 4 228 ? 108.312 63.812  70.747  1.00 88.55  ? 228 TYR E CE1 1 
ATOM 6427 C CE2 . TYR D 4 228 ? 109.443 65.454  69.427  1.00 90.18  ? 228 TYR E CE2 1 
ATOM 6428 C CZ  . TYR D 4 228 ? 109.347 64.166  69.909  1.00 92.02  ? 228 TYR E CZ  1 
ATOM 6429 O OH  . TYR D 4 228 ? 110.288 63.229  69.551  1.00 92.27  ? 228 TYR E OH  1 
ATOM 6430 N N   . CYS D 4 229 ? 103.128 67.554  71.407  1.00 90.37  ? 229 CYS E N   1 
ATOM 6431 C CA  . CYS D 4 229 ? 102.192 68.390  72.146  1.00 90.66  ? 229 CYS E CA  1 
ATOM 6432 C C   . CYS D 4 229 ? 102.475 68.296  73.639  1.00 93.01  ? 229 CYS E C   1 
ATOM 6433 O O   . CYS D 4 229 ? 102.585 67.194  74.187  1.00 95.10  ? 229 CYS E O   1 
ATOM 6434 C CB  . CYS D 4 229 ? 100.740 68.002  71.854  1.00 95.75  ? 229 CYS E CB  1 
ATOM 6435 S SG  . CYS D 4 229 ? 100.317 66.260  72.080  1.00 104.18 ? 229 CYS E SG  1 
ATOM 6436 N N   . MET D 4 230 ? 102.592 69.451  74.290  1.00 80.93  ? 230 MET E N   1 
ATOM 6437 C CA  . MET D 4 230 ? 102.872 69.539  75.716  1.00 82.08  ? 230 MET E CA  1 
ATOM 6438 C C   . MET D 4 230 ? 101.752 70.313  76.395  1.00 79.72  ? 230 MET E C   1 
ATOM 6439 O O   . MET D 4 230 ? 101.209 71.265  75.824  1.00 74.23  ? 230 MET E O   1 
ATOM 6440 C CB  . MET D 4 230 ? 104.218 70.220  75.980  1.00 78.37  ? 230 MET E CB  1 
ATOM 6441 C CG  . MET D 4 230 ? 104.681 70.143  77.425  1.00 77.33  ? 230 MET E CG  1 
ATOM 6442 S SD  . MET D 4 230 ? 105.999 71.315  77.782  1.00 75.27  ? 230 MET E SD  1 
ATOM 6443 C CE  . MET D 4 230 ? 105.119 72.864  77.600  1.00 83.10  ? 230 MET E CE  1 
ATOM 6444 N N   . GLN D 4 231 ? 101.409 69.909  77.614  1.00 78.88  ? 231 GLN E N   1 
ATOM 6445 C CA  . GLN D 4 231 ? 100.429 70.620  78.421  1.00 78.22  ? 231 GLN E CA  1 
ATOM 6446 C C   . GLN D 4 231 ? 101.128 71.480  79.466  1.00 79.96  ? 231 GLN E C   1 
ATOM 6447 O O   . GLN D 4 231 ? 102.120 71.060  80.070  1.00 82.64  ? 231 GLN E O   1 
ATOM 6448 C CB  . GLN D 4 231 ? 99.463  69.638  79.092  1.00 77.51  ? 231 GLN E CB  1 
ATOM 6449 C CG  . GLN D 4 231 ? 100.119 68.597  79.993  1.00 73.49  ? 231 GLN E CG  1 
ATOM 6450 C CD  . GLN D 4 231 ? 100.225 69.046  81.435  1.00 69.06  ? 231 GLN E CD  1 
ATOM 6451 O OE1 . GLN D 4 231 ? 99.612  70.034  81.836  1.00 71.69  ? 231 GLN E OE1 1 
ATOM 6452 N NE2 . GLN D 4 231 ? 101.002 68.315  82.225  1.00 75.12  ? 231 GLN E NE2 1 
ATOM 6453 N N   . HIS D 4 232 ? 100.611 72.695  79.664  1.00 82.64  ? 232 HIS E N   1 
ATOM 6454 C CA  . HIS D 4 232 ? 101.099 73.593  80.705  1.00 82.07  ? 232 HIS E CA  1 
ATOM 6455 C C   . HIS D 4 232 ? 99.990  74.017  81.661  1.00 84.04  ? 232 HIS E C   1 
ATOM 6456 O O   . HIS D 4 232 ? 100.089 75.075  82.291  1.00 84.09  ? 232 HIS E O   1 
ATOM 6457 C CB  . HIS D 4 232 ? 101.767 74.823  80.089  1.00 73.98  ? 232 HIS E CB  1 
ATOM 6458 C CG  . HIS D 4 232 ? 102.783 75.467  80.980  1.00 76.54  ? 232 HIS E CG  1 
ATOM 6459 N ND1 . HIS D 4 232 ? 102.782 75.305  82.349  1.00 76.81  ? 232 HIS E ND1 1 
ATOM 6460 C CD2 . HIS D 4 232 ? 103.836 76.269  80.698  1.00 80.07  ? 232 HIS E CD2 1 
ATOM 6461 C CE1 . HIS D 4 232 ? 103.789 75.983  82.871  1.00 73.97  ? 232 HIS E CE1 1 
ATOM 6462 N NE2 . HIS D 4 232 ? 104.444 76.577  81.891  1.00 73.27  ? 232 HIS E NE2 1 
ATOM 6463 N N   . LEU D 4 233 ? 98.930  73.215  81.780  1.00 86.04  ? 233 LEU E N   1 
ATOM 6464 C CA  . LEU D 4 233 ? 97.851  73.555  82.702  1.00 80.51  ? 233 LEU E CA  1 
ATOM 6465 C C   . LEU D 4 233 ? 98.330  73.489  84.145  1.00 75.62  ? 233 LEU E C   1 
ATOM 6466 O O   . LEU D 4 233 ? 97.963  74.335  84.968  1.00 84.56  ? 233 LEU E O   1 
ATOM 6467 C CB  . LEU D 4 233 ? 96.663  72.620  82.489  1.00 81.38  ? 233 LEU E CB  1 
ATOM 6468 C CG  . LEU D 4 233 ? 95.481  72.818  83.439  1.00 80.55  ? 233 LEU E CG  1 
ATOM 6469 C CD1 . LEU D 4 233 ? 94.835  74.181  83.227  1.00 76.85  ? 233 LEU E CD1 1 
ATOM 6470 C CD2 . LEU D 4 233 ? 94.465  71.702  83.278  1.00 86.40  ? 233 LEU E CD2 1 
ATOM 6471 N N   . GLU D 4 234 ? 99.154  72.496  84.466  1.00 67.64  ? 234 GLU E N   1 
ATOM 6472 C CA  . GLU D 4 234 ? 99.650  72.309  85.820  1.00 71.16  ? 234 GLU E CA  1 
ATOM 6473 C C   . GLU D 4 234 ? 100.923 71.481  85.756  1.00 78.42  ? 234 GLU E C   1 
ATOM 6474 O O   . GLU D 4 234 ? 101.209 70.823  84.753  1.00 86.59  ? 234 GLU E O   1 
ATOM 6475 C CB  . GLU D 4 234 ? 98.603  71.636  86.715  1.00 74.08  ? 234 GLU E CB  1 
ATOM 6476 C CG  . GLU D 4 234 ? 98.249  70.217  86.298  1.00 76.86  ? 234 GLU E CG  1 
ATOM 6477 C CD  . GLU D 4 234 ? 97.306  69.541  87.275  1.00 85.95  ? 234 GLU E CD  1 
ATOM 6478 O OE1 . GLU D 4 234 ? 96.863  70.209  88.232  1.00 85.75  ? 234 GLU E OE1 1 
ATOM 6479 O OE2 . GLU D 4 234 ? 97.009  68.342  87.087  1.00 84.82  ? 234 GLU E OE2 1 
ATOM 6480 N N   . TYR D 4 235 ? 101.681 71.522  86.845  1.00 67.42  ? 235 TYR E N   1 
ATOM 6481 C CA  . TYR D 4 235 ? 102.905 70.746  86.988  1.00 64.04  ? 235 TYR E CA  1 
ATOM 6482 C C   . TYR D 4 235 ? 102.600 69.378  87.591  1.00 63.90  ? 235 TYR E C   1 
ATOM 6483 O O   . TYR D 4 235 ? 101.711 69.260  88.440  1.00 64.75  ? 235 TYR E O   1 
ATOM 6484 C CB  . TYR D 4 235 ? 103.910 71.484  87.868  1.00 59.99  ? 235 TYR E CB  1 
ATOM 6485 C CG  . TYR D 4 235 ? 104.429 72.763  87.252  1.00 59.50  ? 235 TYR E CG  1 
ATOM 6486 C CD1 . TYR D 4 235 ? 103.735 73.958  87.388  1.00 62.64  ? 235 TYR E CD1 1 
ATOM 6487 C CD2 . TYR D 4 235 ? 105.613 72.774  86.529  1.00 64.34  ? 235 TYR E CD2 1 
ATOM 6488 C CE1 . TYR D 4 235 ? 104.207 75.127  86.822  1.00 66.22  ? 235 TYR E CE1 1 
ATOM 6489 C CE2 . TYR D 4 235 ? 106.093 73.937  85.961  1.00 64.22  ? 235 TYR E CE2 1 
ATOM 6490 C CZ  . TYR D 4 235 ? 105.387 75.111  86.110  1.00 66.31  ? 235 TYR E CZ  1 
ATOM 6491 O OH  . TYR D 4 235 ? 105.863 76.272  85.544  1.00 62.60  ? 235 TYR E OH  1 
ATOM 6492 N N   . PRO D 4 236 ? 103.316 68.322  87.178  1.00 64.71  ? 236 PRO E N   1 
ATOM 6493 C CA  . PRO D 4 236 ? 104.455 68.297  86.245  1.00 61.70  ? 236 PRO E CA  1 
ATOM 6494 C C   . PRO D 4 236 ? 104.066 68.389  84.770  1.00 65.44  ? 236 PRO E C   1 
ATOM 6495 O O   . PRO D 4 236 ? 103.063 67.823  84.341  1.00 72.49  ? 236 PRO E O   1 
ATOM 6496 C CB  . PRO D 4 236 ? 105.118 66.954  86.567  1.00 68.35  ? 236 PRO E CB  1 
ATOM 6497 C CG  . PRO D 4 236 ? 103.972 66.075  86.953  1.00 68.90  ? 236 PRO E CG  1 
ATOM 6498 C CD  . PRO D 4 236 ? 103.022 66.977  87.707  1.00 70.52  ? 236 PRO E CD  1 
ATOM 6499 N N   . LEU D 4 237 ? 104.854 69.112  83.978  1.00 68.22  ? 237 LEU E N   1 
ATOM 6500 C CA  . LEU D 4 237 ? 104.621 69.189  82.542  1.00 67.17  ? 237 LEU E CA  1 
ATOM 6501 C C   . LEU D 4 237 ? 104.918 67.847  81.883  1.00 71.21  ? 237 LEU E C   1 
ATOM 6502 O O   . LEU D 4 237 ? 105.982 67.258  82.099  1.00 68.22  ? 237 LEU E O   1 
ATOM 6503 C CB  . LEU D 4 237 ? 105.492 70.283  81.929  1.00 60.13  ? 237 LEU E CB  1 
ATOM 6504 C CG  . LEU D 4 237 ? 105.413 71.649  82.612  1.00 57.59  ? 237 LEU E CG  1 
ATOM 6505 C CD1 . LEU D 4 237 ? 106.401 72.623  81.990  1.00 62.33  ? 237 LEU E CD1 1 
ATOM 6506 C CD2 . LEU D 4 237 ? 104.001 72.196  82.536  1.00 63.40  ? 237 LEU E CD2 1 
ATOM 6507 N N   . THR D 4 238 ? 103.974 67.362  81.081  1.00 80.57  ? 238 THR E N   1 
ATOM 6508 C CA  . THR D 4 238 ? 104.076 66.063  80.431  1.00 78.10  ? 238 THR E CA  1 
ATOM 6509 C C   . THR D 4 238 ? 103.996 66.228  78.920  1.00 81.05  ? 238 THR E C   1 
ATOM 6510 O O   . THR D 4 238 ? 103.269 67.091  78.418  1.00 78.50  ? 238 THR E O   1 
ATOM 6511 C CB  . THR D 4 238 ? 102.979 65.115  80.915  1.00 81.75  ? 238 THR E CB  1 
ATOM 6512 O OG1 . THR D 4 238 ? 101.696 65.718  80.706  1.00 88.49  ? 238 THR E OG1 1 
ATOM 6513 C CG2 . THR D 4 238 ? 103.158 64.810  82.395  1.00 83.27  ? 238 THR E CG2 1 
ATOM 6514 N N   . PHE D 4 239 ? 104.745 65.395  78.202  1.00 93.06  ? 239 PHE E N   1 
ATOM 6515 C CA  . PHE D 4 239 ? 104.797 65.432  76.748  1.00 92.98  ? 239 PHE E CA  1 
ATOM 6516 C C   . PHE D 4 239 ? 104.036 64.253  76.156  1.00 94.67  ? 239 PHE E C   1 
ATOM 6517 O O   . PHE D 4 239 ? 103.901 63.198  76.783  1.00 92.88  ? 239 PHE E O   1 
ATOM 6518 C CB  . PHE D 4 239 ? 106.245 65.405  76.249  1.00 89.85  ? 239 PHE E CB  1 
ATOM 6519 C CG  . PHE D 4 239 ? 107.028 66.639  76.588  1.00 89.39  ? 239 PHE E CG  1 
ATOM 6520 C CD1 . PHE D 4 239 ? 107.700 66.737  77.794  1.00 89.76  ? 239 PHE E CD1 1 
ATOM 6521 C CD2 . PHE D 4 239 ? 107.095 67.699  75.700  1.00 89.53  ? 239 PHE E CD2 1 
ATOM 6522 C CE1 . PHE D 4 239 ? 108.424 67.869  78.108  1.00 93.86  ? 239 PHE E CE1 1 
ATOM 6523 C CE2 . PHE D 4 239 ? 107.816 68.834  76.009  1.00 90.08  ? 239 PHE E CE2 1 
ATOM 6524 C CZ  . PHE D 4 239 ? 108.482 68.919  77.214  1.00 90.73  ? 239 PHE E CZ  1 
ATOM 6525 N N   . GLY D 4 240 ? 103.539 64.445  74.933  1.00 91.47  ? 240 GLY E N   1 
ATOM 6526 C CA  . GLY D 4 240 ? 103.002 63.348  74.159  1.00 90.75  ? 240 GLY E CA  1 
ATOM 6527 C C   . GLY D 4 240 ? 104.086 62.470  73.562  1.00 88.87  ? 240 GLY E C   1 
ATOM 6528 O O   . GLY D 4 240 ? 105.273 62.793  73.585  1.00 86.69  ? 240 GLY E O   1 
ATOM 6529 N N   . ALA D 4 241 ? 103.652 61.326  73.026  1.00 100.56 ? 241 ALA E N   1 
ATOM 6530 C CA  . ALA D 4 241 ? 104.590 60.400  72.398  1.00 103.92 ? 241 ALA E CA  1 
ATOM 6531 C C   . ALA D 4 241 ? 105.295 61.043  71.210  1.00 106.04 ? 241 ALA E C   1 
ATOM 6532 O O   . ALA D 4 241 ? 106.496 60.835  71.004  1.00 106.97 ? 241 ALA E O   1 
ATOM 6533 C CB  . ALA D 4 241 ? 103.862 59.127  71.967  1.00 103.55 ? 241 ALA E CB  1 
ATOM 6534 N N   . GLY D 4 242 ? 104.571 61.822  70.423  1.00 106.29 ? 242 GLY E N   1 
ATOM 6535 C CA  . GLY D 4 242 ? 105.143 62.490  69.265  1.00 103.34 ? 242 GLY E CA  1 
ATOM 6536 C C   . GLY D 4 242 ? 104.632 61.895  67.965  1.00 106.43 ? 242 GLY E C   1 
ATOM 6537 O O   . GLY D 4 242 ? 104.472 60.675  67.833  1.00 110.21 ? 242 GLY E O   1 
ATOM 6538 N N   . THR D 4 243 ? 104.371 62.765  66.992  1.00 100.93 ? 243 THR E N   1 
ATOM 6539 C CA  . THR D 4 243 ? 103.934 62.364  65.660  1.00 101.09 ? 243 THR E CA  1 
ATOM 6540 C C   . THR D 4 243 ? 105.010 62.749  64.654  1.00 99.93  ? 243 THR E C   1 
ATOM 6541 O O   . THR D 4 243 ? 105.363 63.928  64.539  1.00 104.43 ? 243 THR E O   1 
ATOM 6542 C CB  . THR D 4 243 ? 102.604 63.022  65.295  1.00 101.48 ? 243 THR E CB  1 
ATOM 6543 O OG1 . THR D 4 243 ? 101.590 62.600  66.216  1.00 106.49 ? 243 THR E OG1 1 
ATOM 6544 C CG2 . THR D 4 243 ? 102.191 62.639  63.883  1.00 101.76 ? 243 THR E CG2 1 
ATOM 6545 N N   . LYS D 4 244 ? 105.524 61.761  63.928  1.00 106.38 ? 244 LYS E N   1 
ATOM 6546 C CA  . LYS D 4 244 ? 106.592 61.968  62.959  1.00 108.98 ? 244 LYS E CA  1 
ATOM 6547 C C   . LYS D 4 244 ? 106.004 62.131  61.563  1.00 108.11 ? 244 LYS E C   1 
ATOM 6548 O O   . LYS D 4 244 ? 105.120 61.367  61.164  1.00 107.35 ? 244 LYS E O   1 
ATOM 6549 C CB  . LYS D 4 244 ? 107.579 60.800  62.981  1.00 108.50 ? 244 LYS E CB  1 
ATOM 6550 C CG  . LYS D 4 244 ? 108.747 60.959  62.022  1.00 107.45 ? 244 LYS E CG  1 
ATOM 6551 C CD  . LYS D 4 244 ? 109.687 59.768  62.092  1.00 108.02 ? 244 LYS E CD  1 
ATOM 6552 C CE  . LYS D 4 244 ? 110.849 59.930  61.126  1.00 106.43 ? 244 LYS E CE  1 
ATOM 6553 N NZ  . LYS D 4 244 ? 111.781 58.772  61.185  1.00 107.72 ? 244 LYS E NZ  1 
ATOM 6554 N N   . LEU D 4 245 ? 106.494 63.125  60.828  1.00 119.42 ? 245 LEU E N   1 
ATOM 6555 C CA  . LEU D 4 245 ? 106.136 63.320  59.430  1.00 121.19 ? 245 LEU E CA  1 
ATOM 6556 C C   . LEU D 4 245 ? 107.302 62.885  58.555  1.00 123.38 ? 245 LEU E C   1 
ATOM 6557 O O   . LEU D 4 245 ? 108.435 63.335  58.755  1.00 122.04 ? 245 LEU E O   1 
ATOM 6558 C CB  . LEU D 4 245 ? 105.777 64.781  59.143  1.00 122.38 ? 245 LEU E CB  1 
ATOM 6559 C CG  . LEU D 4 245 ? 104.504 65.340  59.782  1.00 120.62 ? 245 LEU E CG  1 
ATOM 6560 C CD1 . LEU D 4 245 ? 104.096 66.637  59.102  1.00 120.15 ? 245 LEU E CD1 1 
ATOM 6561 C CD2 . LEU D 4 245 ? 103.375 64.327  59.726  1.00 118.91 ? 245 LEU E CD2 1 
ATOM 6562 N N   . GLU D 4 246 ? 107.024 62.010  57.591  1.00 134.45 ? 246 GLU E N   1 
ATOM 6563 C CA  . GLU D 4 246 ? 108.037 61.497  56.682  1.00 133.79 ? 246 GLU E CA  1 
ATOM 6564 C C   . GLU D 4 246 ? 107.530 61.573  55.250  1.00 132.69 ? 246 GLU E C   1 
ATOM 6565 O O   . GLU D 4 246 ? 106.328 61.472  54.991  1.00 134.44 ? 246 GLU E O   1 
ATOM 6566 C CB  . GLU D 4 246 ? 108.422 60.052  57.028  1.00 133.82 ? 246 GLU E CB  1 
ATOM 6567 C CG  . GLU D 4 246 ? 107.245 59.092  57.084  1.00 133.22 ? 246 GLU E CG  1 
ATOM 6568 C CD  . GLU D 4 246 ? 107.652 57.699  57.521  1.00 131.51 ? 246 GLU E CD  1 
ATOM 6569 O OE1 . GLU D 4 246 ? 108.857 57.478  57.763  1.00 132.51 ? 246 GLU E OE1 1 
ATOM 6570 O OE2 . GLU D 4 246 ? 106.765 56.826  57.626  1.00 130.34 ? 246 GLU E OE2 1 
ATOM 6571 N N   . LEU D 4 247 ? 108.463 61.755  54.320  1.00 130.24 ? 247 LEU E N   1 
ATOM 6572 C CA  . LEU D 4 247 ? 108.129 61.849  52.904  1.00 131.99 ? 247 LEU E CA  1 
ATOM 6573 C C   . LEU D 4 247 ? 108.071 60.467  52.260  1.00 130.86 ? 247 LEU E C   1 
ATOM 6574 O O   . LEU D 4 247 ? 108.670 60.235  51.211  1.00 130.14 ? 247 LEU E O   1 
ATOM 6575 C CB  . LEU D 4 247 ? 109.144 62.729  52.173  1.00 132.20 ? 247 LEU E CB  1 
ATOM 6576 C CG  . LEU D 4 247 ? 109.238 64.178  52.653  1.00 131.45 ? 247 LEU E CG  1 
ATOM 6577 C CD1 . LEU D 4 247 ? 110.301 64.935  51.873  1.00 130.53 ? 247 LEU E CD1 1 
ATOM 6578 C CD2 . LEU D 4 247 ? 107.888 64.867  52.534  1.00 130.99 ? 247 LEU E CD2 1 
ATOM 6579 N N   . TYR E 5 160 ? 78.553  102.678 146.182 1.00 153.87 ? 107 TYR R N   1 
ATOM 6580 C CA  . TYR E 5 160 ? 79.221  103.535 145.209 1.00 154.91 ? 107 TYR R CA  1 
ATOM 6581 C C   . TYR E 5 160 ? 80.602  102.992 144.859 1.00 155.69 ? 107 TYR R C   1 
ATOM 6582 O O   . TYR E 5 160 ? 81.051  103.100 143.718 1.00 155.35 ? 107 TYR R O   1 
ATOM 6583 C CB  . TYR E 5 160 ? 79.336  104.964 145.742 1.00 153.51 ? 107 TYR R CB  1 
ATOM 6584 N N   . ILE E 5 161 ? 81.276  102.414 145.858 1.00 157.70 ? 108 ILE R N   1 
ATOM 6585 C CA  . ILE E 5 161 ? 82.614  101.870 145.640 1.00 157.68 ? 108 ILE R CA  1 
ATOM 6586 C C   . ILE E 5 161 ? 82.570  100.725 144.638 1.00 158.81 ? 108 ILE R C   1 
ATOM 6587 O O   . ILE E 5 161 ? 83.480  100.564 143.815 1.00 158.23 ? 108 ILE R O   1 
ATOM 6588 C CB  . ILE E 5 161 ? 83.235  101.429 146.978 1.00 155.90 ? 108 ILE R CB  1 
ATOM 6589 N N   . ASN E 5 162 ? 81.516  99.909  144.690 1.00 158.57 ? 109 ASN R N   1 
ATOM 6590 C CA  . ASN E 5 162 ? 81.375  98.783  143.777 1.00 158.29 ? 109 ASN R CA  1 
ATOM 6591 C C   . ASN E 5 162 ? 80.962  99.202  142.372 1.00 158.23 ? 109 ASN R C   1 
ATOM 6592 O O   . ASN E 5 162 ? 80.917  98.349  141.479 1.00 158.45 ? 109 ASN R O   1 
ATOM 6593 C CB  . ASN E 5 162 ? 80.357  97.783  144.332 1.00 156.85 ? 109 ASN R CB  1 
ATOM 6594 N N   . ILE E 5 163 ? 80.658  100.480 142.156 1.00 151.42 ? 110 ILE R N   1 
ATOM 6595 C CA  . ILE E 5 163 ? 80.211  100.956 140.858 1.00 150.65 ? 110 ILE R CA  1 
ATOM 6596 C C   . ILE E 5 163 ? 81.196  101.932 140.222 1.00 150.01 ? 110 ILE R C   1 
ATOM 6597 O O   . ILE E 5 163 ? 81.277  101.994 138.990 1.00 149.60 ? 110 ILE R O   1 
ATOM 6598 C CB  . ILE E 5 163 ? 78.808  101.590 140.962 1.00 150.03 ? 110 ILE R CB  1 
ATOM 6599 N N   . ILE E 5 164 ? 81.942  102.695 141.022 1.00 151.84 ? 111 ILE R N   1 
ATOM 6600 C CA  . ILE E 5 164 ? 82.880  103.669 140.471 1.00 152.72 ? 111 ILE R CA  1 
ATOM 6601 C C   . ILE E 5 164 ? 84.059  102.963 139.812 1.00 152.65 ? 111 ILE R C   1 
ATOM 6602 O O   . ILE E 5 164 ? 84.447  103.287 138.684 1.00 152.39 ? 111 ILE R O   1 
ATOM 6603 C CB  . ILE E 5 164 ? 83.347  104.644 141.567 1.00 151.30 ? 111 ILE R CB  1 
ATOM 6604 N N   . MET E 5 165 ? 84.646  101.990 140.508 1.00 150.81 ? 112 MET R N   1 
ATOM 6605 C CA  . MET E 5 165 ? 85.832  101.311 139.987 1.00 150.47 ? 112 MET R CA  1 
ATOM 6606 C C   . MET E 5 165 ? 85.571  100.549 138.693 1.00 149.90 ? 112 MET R C   1 
ATOM 6607 O O   . MET E 5 165 ? 86.381  100.681 137.758 1.00 149.59 ? 112 MET R O   1 
ATOM 6608 C CB  . MET E 5 165 ? 86.413  100.392 141.068 1.00 150.97 ? 112 MET R CB  1 
ATOM 6609 C CG  . MET E 5 165 ? 87.598  99.568  140.600 1.00 151.34 ? 112 MET R CG  1 
ATOM 6610 S SD  . MET E 5 165 ? 88.234  98.464  141.874 1.00 153.85 ? 112 MET R SD  1 
ATOM 6611 C CE  . MET E 5 165 ? 89.528  97.627  140.965 1.00 151.49 ? 112 MET R CE  1 
ATOM 6612 N N   . PRO E 5 166 ? 84.510  99.742  138.558 1.00 145.13 ? 113 PRO R N   1 
ATOM 6613 C CA  . PRO E 5 166 ? 84.266  99.101  137.254 1.00 145.39 ? 113 PRO R CA  1 
ATOM 6614 C C   . PRO E 5 166 ? 84.043  100.087 136.122 1.00 146.67 ? 113 PRO R C   1 
ATOM 6615 O O   . PRO E 5 166 ? 84.419  99.798  134.979 1.00 145.64 ? 113 PRO R O   1 
ATOM 6616 C CB  . PRO E 5 166 ? 83.015  98.247  137.512 1.00 145.00 ? 113 PRO R CB  1 
ATOM 6617 C CG  . PRO E 5 166 ? 83.004  98.023  138.979 1.00 145.75 ? 113 PRO R CG  1 
ATOM 6618 C CD  . PRO E 5 166 ? 83.538  99.288  139.570 1.00 145.20 ? 113 PRO R CD  1 
ATOM 6619 N N   . SER E 5 167 ? 83.438  101.244 136.401 1.00 147.96 ? 114 SER R N   1 
ATOM 6620 C CA  . SER E 5 167 ? 83.192  102.222 135.346 1.00 147.50 ? 114 SER R CA  1 
ATOM 6621 C C   . SER E 5 167 ? 84.489  102.873 134.877 1.00 145.89 ? 114 SER R C   1 
ATOM 6622 O O   . SER E 5 167 ? 84.639  103.185 133.690 1.00 142.84 ? 114 SER R O   1 
ATOM 6623 C CB  . SER E 5 167 ? 82.205  103.282 135.833 1.00 146.97 ? 114 SER R CB  1 
ATOM 6624 O OG  . SER E 5 167 ? 82.702  103.955 136.976 1.00 147.36 ? 114 SER R OG  1 
ATOM 6625 N N   . VAL E 5 168 ? 85.432  103.091 135.796 1.00 143.20 ? 115 VAL R N   1 
ATOM 6626 C CA  . VAL E 5 168 ? 86.703  103.714 135.435 1.00 141.16 ? 115 VAL R CA  1 
ATOM 6627 C C   . VAL E 5 168 ? 87.498  102.815 134.495 1.00 140.43 ? 115 VAL R C   1 
ATOM 6628 O O   . VAL E 5 168 ? 88.011  103.267 133.465 1.00 142.17 ? 115 VAL R O   1 
ATOM 6629 C CB  . VAL E 5 168 ? 87.508  104.061 136.700 1.00 142.21 ? 115 VAL R CB  1 
ATOM 6630 C CG1 . VAL E 5 168 ? 88.915  104.504 136.330 1.00 141.35 ? 115 VAL R CG1 1 
ATOM 6631 C CG2 . VAL E 5 168 ? 86.802  105.147 137.495 1.00 142.51 ? 115 VAL R CG2 1 
ATOM 6632 N N   . PHE E 5 169 ? 87.612  101.529 134.834 1.00 131.83 ? 116 PHE R N   1 
ATOM 6633 C CA  . PHE E 5 169 ? 88.332  100.600 133.967 1.00 130.69 ? 116 PHE R CA  1 
ATOM 6634 C C   . PHE E 5 169 ? 87.629  100.427 132.627 1.00 130.77 ? 116 PHE R C   1 
ATOM 6635 O O   . PHE E 5 169 ? 88.285  100.368 131.580 1.00 130.31 ? 116 PHE R O   1 
ATOM 6636 C CB  . PHE E 5 169 ? 88.501  99.252  134.666 1.00 130.74 ? 116 PHE R CB  1 
ATOM 6637 C CG  . PHE E 5 169 ? 89.575  99.244  135.715 1.00 132.79 ? 116 PHE R CG  1 
ATOM 6638 C CD1 . PHE E 5 169 ? 90.880  98.915  135.386 1.00 130.10 ? 116 PHE R CD1 1 
ATOM 6639 C CD2 . PHE E 5 169 ? 89.282  99.567  137.030 1.00 133.18 ? 116 PHE R CD2 1 
ATOM 6640 C CE1 . PHE E 5 169 ? 91.872  98.907  136.349 1.00 131.22 ? 116 PHE R CE1 1 
ATOM 6641 C CE2 . PHE E 5 169 ? 90.270  99.560  137.997 1.00 132.50 ? 116 PHE R CE2 1 
ATOM 6642 C CZ  . PHE E 5 169 ? 91.566  99.230  137.656 1.00 133.10 ? 116 PHE R CZ  1 
ATOM 6643 N N   . GLY E 5 170 ? 86.297  100.335 132.637 1.00 128.37 ? 117 GLY R N   1 
ATOM 6644 C CA  . GLY E 5 170 ? 85.572  100.152 131.390 1.00 129.27 ? 117 GLY R CA  1 
ATOM 6645 C C   . GLY E 5 170 ? 85.693  101.348 130.464 1.00 129.15 ? 117 GLY R C   1 
ATOM 6646 O O   . GLY E 5 170 ? 85.821  101.191 129.246 1.00 128.27 ? 117 GLY R O   1 
ATOM 6647 N N   . THR E 5 171 ? 85.648  102.558 131.027 1.00 129.70 ? 118 THR R N   1 
ATOM 6648 C CA  . THR E 5 171 ? 85.822  103.763 130.222 1.00 129.27 ? 118 THR R CA  1 
ATOM 6649 C C   . THR E 5 171 ? 87.213  103.818 129.601 1.00 126.86 ? 118 THR R C   1 
ATOM 6650 O O   . THR E 5 171 ? 87.364  104.178 128.427 1.00 125.40 ? 118 THR R O   1 
ATOM 6651 C CB  . THR E 5 171 ? 85.566  105.006 131.074 1.00 131.76 ? 118 THR R CB  1 
ATOM 6652 O OG1 . THR E 5 171 ? 84.267  104.917 131.673 1.00 131.56 ? 118 THR R OG1 1 
ATOM 6653 C CG2 . THR E 5 171 ? 85.640  106.265 130.222 1.00 129.93 ? 118 THR R CG2 1 
ATOM 6654 N N   . ILE E 5 172 ? 88.243  103.467 130.375 1.00 120.65 ? 119 ILE R N   1 
ATOM 6655 C CA  . ILE E 5 172 ? 89.608  103.472 129.855 1.00 119.74 ? 119 ILE R CA  1 
ATOM 6656 C C   . ILE E 5 172 ? 89.763  102.438 128.747 1.00 119.48 ? 119 ILE R C   1 
ATOM 6657 O O   . ILE E 5 172 ? 90.404  102.696 127.720 1.00 119.04 ? 119 ILE R O   1 
ATOM 6658 C CB  . ILE E 5 172 ? 90.613  103.233 130.998 1.00 120.35 ? 119 ILE R CB  1 
ATOM 6659 C CG1 . ILE E 5 172 ? 90.623  104.422 131.960 1.00 121.45 ? 119 ILE R CG1 1 
ATOM 6660 C CG2 . ILE E 5 172 ? 92.006  102.979 130.446 1.00 117.53 ? 119 ILE R CG2 1 
ATOM 6661 C CD1 . ILE E 5 172 ? 91.540  104.235 133.150 1.00 120.78 ? 119 ILE R CD1 1 
ATOM 6662 N N   . CYS E 5 173 ? 89.175  101.253 128.934 1.00 117.28 ? 120 CYS R N   1 
ATOM 6663 C CA  . CYS E 5 173 ? 89.314  100.193 127.941 1.00 117.07 ? 120 CYS R CA  1 
ATOM 6664 C C   . CYS E 5 173 ? 88.667  100.577 126.616 1.00 116.39 ? 120 CYS R C   1 
ATOM 6665 O O   . CYS E 5 173 ? 89.255  100.373 125.548 1.00 110.76 ? 120 CYS R O   1 
ATOM 6666 C CB  . CYS E 5 173 ? 88.705  98.896  128.473 1.00 117.23 ? 120 CYS R CB  1 
ATOM 6667 S SG  . CYS E 5 173 ? 88.835  97.492  127.344 1.00 123.60 ? 120 CYS R SG  1 
ATOM 6668 N N   . LEU E 5 174 ? 87.460  101.143 126.665 1.00 113.71 ? 121 LEU R N   1 
ATOM 6669 C CA  . LEU E 5 174 ? 86.756  101.490 125.434 1.00 110.18 ? 121 LEU R CA  1 
ATOM 6670 C C   . LEU E 5 174 ? 87.389  102.690 124.740 1.00 110.13 ? 121 LEU R C   1 
ATOM 6671 O O   . LEU E 5 174 ? 87.556  102.684 123.515 1.00 107.87 ? 121 LEU R O   1 
ATOM 6672 C CB  . LEU E 5 174 ? 85.282  101.761 125.734 1.00 110.00 ? 121 LEU R CB  1 
ATOM 6673 C CG  . LEU E 5 174 ? 84.478  100.576 126.271 1.00 111.33 ? 121 LEU R CG  1 
ATOM 6674 C CD1 . LEU E 5 174 ? 83.036  100.980 126.529 1.00 110.38 ? 121 LEU R CD1 1 
ATOM 6675 C CD2 . LEU E 5 174 ? 84.543  99.403  125.304 1.00 110.58 ? 121 LEU R CD2 1 
ATOM 6676 N N   . LEU E 5 175 ? 87.745  103.728 125.501 1.00 107.61 ? 122 LEU R N   1 
ATOM 6677 C CA  . LEU E 5 175 ? 88.295  104.934 124.889 1.00 105.85 ? 122 LEU R CA  1 
ATOM 6678 C C   . LEU E 5 175 ? 89.639  104.661 124.223 1.00 105.05 ? 122 LEU R C   1 
ATOM 6679 O O   . LEU E 5 175 ? 89.933  105.217 123.158 1.00 106.76 ? 122 LEU R O   1 
ATOM 6680 C CB  . LEU E 5 175 ? 88.429  106.041 125.936 1.00 106.84 ? 122 LEU R CB  1 
ATOM 6681 C CG  . LEU E 5 175 ? 88.936  107.397 125.439 1.00 107.45 ? 122 LEU R CG  1 
ATOM 6682 C CD1 . LEU E 5 175 ? 87.976  107.990 124.419 1.00 107.73 ? 122 LEU R CD1 1 
ATOM 6683 C CD2 . LEU E 5 175 ? 89.146  108.355 126.603 1.00 105.37 ? 122 LEU R CD2 1 
ATOM 6684 N N   . GLY E 5 176 ? 90.470  103.812 124.832 1.00 98.03  ? 123 GLY R N   1 
ATOM 6685 C CA  . GLY E 5 176 ? 91.752  103.494 124.231 1.00 96.66  ? 123 GLY R CA  1 
ATOM 6686 C C   . GLY E 5 176 ? 91.666  102.540 123.059 1.00 98.92  ? 123 GLY R C   1 
ATOM 6687 O O   . GLY E 5 176 ? 92.531  102.563 122.178 1.00 101.89 ? 123 GLY R O   1 
ATOM 6688 N N   . ILE E 5 177 ? 90.637  101.691 123.027 1.00 94.67  ? 124 ILE R N   1 
ATOM 6689 C CA  . ILE E 5 177 ? 90.439  100.813 121.877 1.00 95.97  ? 124 ILE R CA  1 
ATOM 6690 C C   . ILE E 5 177 ? 90.030  101.620 120.649 1.00 95.24  ? 124 ILE R C   1 
ATOM 6691 O O   . ILE E 5 177 ? 90.505  101.364 119.536 1.00 92.95  ? 124 ILE R O   1 
ATOM 6692 C CB  . ILE E 5 177 ? 89.410  99.717  122.213 1.00 99.13  ? 124 ILE R CB  1 
ATOM 6693 C CG1 . ILE E 5 177 ? 90.058  98.624  123.067 1.00 98.47  ? 124 ILE R CG1 1 
ATOM 6694 C CG2 . ILE E 5 177 ? 88.817  99.120  120.945 1.00 97.16  ? 124 ILE R CG2 1 
ATOM 6695 C CD1 . ILE E 5 177 ? 89.112  97.508  123.454 1.00 97.51  ? 124 ILE R CD1 1 
ATOM 6696 N N   . ILE E 5 178 ? 89.149  102.607 120.831 1.00 95.50  ? 125 ILE R N   1 
ATOM 6697 C CA  . ILE E 5 178 ? 88.719  103.441 119.712 1.00 96.91  ? 125 ILE R CA  1 
ATOM 6698 C C   . ILE E 5 178 ? 89.904  104.189 119.116 1.00 98.93  ? 125 ILE R C   1 
ATOM 6699 O O   . ILE E 5 178 ? 90.066  104.253 117.891 1.00 95.16  ? 125 ILE R O   1 
ATOM 6700 C CB  . ILE E 5 178 ? 87.608  104.408 120.161 1.00 98.78  ? 125 ILE R CB  1 
ATOM 6701 C CG1 . ILE E 5 178 ? 86.392  103.630 120.664 1.00 95.51  ? 125 ILE R CG1 1 
ATOM 6702 C CG2 . ILE E 5 178 ? 87.213  105.334 119.022 1.00 98.83  ? 125 ILE R CG2 1 
ATOM 6703 C CD1 . ILE E 5 178 ? 85.279  104.512 121.186 1.00 95.76  ? 125 ILE R CD1 1 
ATOM 6704 N N   . GLY E 5 179 ? 90.749  104.766 119.971 1.00 99.50  ? 126 GLY R N   1 
ATOM 6705 C CA  . GLY E 5 179 ? 91.895  105.509 119.474 1.00 96.57  ? 126 GLY R CA  1 
ATOM 6706 C C   . GLY E 5 179 ? 92.909  104.627 118.772 1.00 96.05  ? 126 GLY R C   1 
ATOM 6707 O O   . GLY E 5 179 ? 93.418  104.981 117.705 1.00 100.12 ? 126 GLY R O   1 
ATOM 6708 N N   . ASN E 5 180 ? 93.222  103.470 119.361 1.00 76.82  ? 127 ASN R N   1 
ATOM 6709 C CA  . ASN E 5 180 ? 94.224  102.585 118.777 1.00 78.00  ? 127 ASN R CA  1 
ATOM 6710 C C   . ASN E 5 180 ? 93.752  102.005 117.449 1.00 79.92  ? 127 ASN R C   1 
ATOM 6711 O O   . ASN E 5 180 ? 94.541  101.879 116.505 1.00 78.86  ? 127 ASN R O   1 
ATOM 6712 C CB  . ASN E 5 180 ? 94.577  101.469 119.759 1.00 82.42  ? 127 ASN R CB  1 
ATOM 6713 C CG  . ASN E 5 180 ? 95.432  101.959 120.909 1.00 82.50  ? 127 ASN R CG  1 
ATOM 6714 O OD1 . ASN E 5 180 ? 96.626  102.208 120.745 1.00 78.68  ? 127 ASN R OD1 1 
ATOM 6715 N ND2 . ASN E 5 180 ? 94.827  102.094 122.083 1.00 84.25  ? 127 ASN R ND2 1 
ATOM 6716 N N   . SER E 5 181 ? 92.470  101.639 117.357 1.00 93.54  ? 128 SER R N   1 
ATOM 6717 C CA  . SER E 5 181 ? 91.934  101.135 116.097 1.00 96.51  ? 128 SER R CA  1 
ATOM 6718 C C   . SER E 5 181 ? 91.950  102.204 115.012 1.00 96.50  ? 128 SER R C   1 
ATOM 6719 O O   . SER E 5 181 ? 92.052  101.880 113.823 1.00 95.87  ? 128 SER R O   1 
ATOM 6720 C CB  . SER E 5 181 ? 90.513  100.609 116.303 1.00 96.10  ? 128 SER R CB  1 
ATOM 6721 O OG  . SER E 5 181 ? 90.484  99.571  117.267 1.00 102.77 ? 128 SER R OG  1 
ATOM 6722 N N   . THR E 5 182 ? 91.847  103.478 115.398 1.00 92.43  ? 129 THR R N   1 
ATOM 6723 C CA  . THR E 5 182 ? 91.922  104.558 114.420 1.00 89.81  ? 129 THR R CA  1 
ATOM 6724 C C   . THR E 5 182 ? 93.332  104.696 113.858 1.00 84.96  ? 129 THR R C   1 
ATOM 6725 O O   . THR E 5 182 ? 93.507  104.920 112.654 1.00 84.05  ? 129 THR R O   1 
ATOM 6726 C CB  . THR E 5 182 ? 91.465  105.873 115.052 1.00 89.27  ? 129 THR R CB  1 
ATOM 6727 O OG1 . THR E 5 182 ? 90.137  105.722 115.570 1.00 91.22  ? 129 THR R OG1 1 
ATOM 6728 C CG2 . THR E 5 182 ? 91.478  106.998 114.027 1.00 88.24  ? 129 THR R CG2 1 
ATOM 6729 N N   . VAL E 5 183 ? 94.348  104.563 114.712 1.00 75.23  ? 130 VAL R N   1 
ATOM 6730 C CA  . VAL E 5 183 ? 95.728  104.688 114.250 1.00 74.21  ? 130 VAL R CA  1 
ATOM 6731 C C   . VAL E 5 183 ? 96.096  103.522 113.338 1.00 76.21  ? 130 VAL R C   1 
ATOM 6732 O O   . VAL E 5 183 ? 96.792  103.702 112.332 1.00 76.69  ? 130 VAL R O   1 
ATOM 6733 C CB  . VAL E 5 183 ? 96.686  104.795 115.451 1.00 70.05  ? 130 VAL R CB  1 
ATOM 6734 C CG1 . VAL E 5 183 ? 98.122  104.940 114.974 1.00 64.51  ? 130 VAL R CG1 1 
ATOM 6735 C CG2 . VAL E 5 183 ? 96.295  105.965 116.342 1.00 73.91  ? 130 VAL R CG2 1 
ATOM 6736 N N   . ILE E 5 184 ? 95.634  102.314 113.669 1.00 81.55  ? 131 ILE R N   1 
ATOM 6737 C CA  . ILE E 5 184 ? 95.935  101.147 112.841 1.00 82.17  ? 131 ILE R CA  1 
ATOM 6738 C C   . ILE E 5 184 ? 95.294  101.292 111.466 1.00 81.34  ? 131 ILE R C   1 
ATOM 6739 O O   . ILE E 5 184 ? 95.933  101.053 110.434 1.00 76.82  ? 131 ILE R O   1 
ATOM 6740 C CB  . ILE E 5 184 ? 95.472  99.857  113.542 1.00 81.42  ? 131 ILE R CB  1 
ATOM 6741 C CG1 . ILE E 5 184 ? 96.238  99.654  114.849 1.00 79.17  ? 131 ILE R CG1 1 
ATOM 6742 C CG2 . ILE E 5 184 ? 95.660  98.656  112.628 1.00 84.35  ? 131 ILE R CG2 1 
ATOM 6743 C CD1 . ILE E 5 184 ? 95.797  98.437  115.631 1.00 78.07  ? 131 ILE R CD1 1 
ATOM 6744 N N   . PHE E 5 185 ? 94.018  101.684 111.433 1.00 89.33  ? 132 PHE R N   1 
ATOM 6745 C CA  . PHE E 5 185 ? 93.303  101.791 110.164 1.00 89.11  ? 132 PHE R CA  1 
ATOM 6746 C C   . PHE E 5 185 ? 93.886  102.890 109.284 1.00 90.75  ? 132 PHE R C   1 
ATOM 6747 O O   . PHE E 5 185 ? 94.021  102.713 108.067 1.00 86.61  ? 132 PHE R O   1 
ATOM 6748 C CB  . PHE E 5 185 ? 91.817  102.038 110.422 1.00 90.43  ? 132 PHE R CB  1 
ATOM 6749 C CG  . PHE E 5 185 ? 90.997  102.174 109.169 1.00 92.32  ? 132 PHE R CG  1 
ATOM 6750 C CD1 . PHE E 5 185 ? 90.578  101.052 108.474 1.00 91.23  ? 132 PHE R CD1 1 
ATOM 6751 C CD2 . PHE E 5 185 ? 90.635  103.424 108.692 1.00 92.30  ? 132 PHE R CD2 1 
ATOM 6752 C CE1 . PHE E 5 185 ? 89.823  101.173 107.323 1.00 90.79  ? 132 PHE R CE1 1 
ATOM 6753 C CE2 . PHE E 5 185 ? 89.880  103.551 107.542 1.00 93.92  ? 132 PHE R CE2 1 
ATOM 6754 C CZ  . PHE E 5 185 ? 89.473  102.424 106.857 1.00 92.63  ? 132 PHE R CZ  1 
ATOM 6755 N N   . ALA E 5 186 ? 94.232  104.034 109.880 1.00 84.93  ? 133 ALA R N   1 
ATOM 6756 C CA  . ALA E 5 186 ? 94.725  105.164 109.098 1.00 77.36  ? 133 ALA R CA  1 
ATOM 6757 C C   . ALA E 5 186 ? 96.079  104.865 108.466 1.00 76.81  ? 133 ALA R C   1 
ATOM 6758 O O   . ALA E 5 186 ? 96.322  105.228 107.310 1.00 84.80  ? 133 ALA R O   1 
ATOM 6759 C CB  . ALA E 5 186 ? 94.804  106.413 109.975 1.00 77.55  ? 133 ALA R CB  1 
ATOM 6760 N N   . VAL E 5 187 ? 96.978  104.214 109.209 1.00 73.53  ? 134 VAL R N   1 
ATOM 6761 C CA  . VAL E 5 187 ? 98.299  103.906 108.669 1.00 78.31  ? 134 VAL R CA  1 
ATOM 6762 C C   . VAL E 5 187 ? 98.195  102.892 107.535 1.00 83.06  ? 134 VAL R C   1 
ATOM 6763 O O   . VAL E 5 187 ? 98.937  102.967 106.548 1.00 82.52  ? 134 VAL R O   1 
ATOM 6764 C CB  . VAL E 5 187 ? 99.225  103.413 109.797 1.00 77.07  ? 134 VAL R CB  1 
ATOM 6765 C CG1 . VAL E 5 187 ? 100.543 102.912 109.235 1.00 73.56  ? 134 VAL R CG1 1 
ATOM 6766 C CG2 . VAL E 5 187 ? 99.468  104.530 110.794 1.00 77.40  ? 134 VAL R CG2 1 
ATOM 6767 N N   . VAL E 5 188 ? 97.268  101.939 107.647 1.00 86.12  ? 135 VAL R N   1 
ATOM 6768 C CA  . VAL E 5 188 ? 97.083  100.966 106.575 1.00 83.15  ? 135 VAL R CA  1 
ATOM 6769 C C   . VAL E 5 188 ? 96.544  101.649 105.324 1.00 83.69  ? 135 VAL R C   1 
ATOM 6770 O O   . VAL E 5 188 ? 96.986  101.363 104.204 1.00 82.00  ? 135 VAL R O   1 
ATOM 6771 C CB  . VAL E 5 188 ? 96.165  99.821  107.043 1.00 83.86  ? 135 VAL R CB  1 
ATOM 6772 C CG1 . VAL E 5 188 ? 95.762  98.943  105.868 1.00 81.94  ? 135 VAL R CG1 1 
ATOM 6773 C CG2 . VAL E 5 188 ? 96.859  98.988  108.111 1.00 81.26  ? 135 VAL R CG2 1 
ATOM 6774 N N   . LYS E 5 189 ? 95.595  102.572 105.490 1.00 85.94  ? 136 LYS R N   1 
ATOM 6775 C CA  . LYS E 5 189 ? 94.938  103.196 104.348 1.00 86.23  ? 136 LYS R CA  1 
ATOM 6776 C C   . LYS E 5 189 ? 95.755  104.319 103.720 1.00 86.25  ? 136 LYS R C   1 
ATOM 6777 O O   . LYS E 5 189 ? 95.391  104.790 102.638 1.00 86.44  ? 136 LYS R O   1 
ATOM 6778 C CB  . LYS E 5 189 ? 93.567  103.736 104.764 1.00 84.10  ? 136 LYS R CB  1 
ATOM 6779 N N   . LYS E 5 190 ? 96.837  104.758 104.359 1.00 86.99  ? 137 LYS R N   1 
ATOM 6780 C CA  . LYS E 5 190 ? 97.713  105.774 103.792 1.00 85.81  ? 137 LYS R CA  1 
ATOM 6781 C C   . LYS E 5 190 ? 98.920  105.172 103.090 1.00 87.65  ? 137 LYS R C   1 
ATOM 6782 O O   . LYS E 5 190 ? 99.796  105.915 102.635 1.00 89.44  ? 137 LYS R O   1 
ATOM 6783 C CB  . LYS E 5 190 ? 98.179  106.742 104.885 1.00 78.69  ? 137 LYS R CB  1 
ATOM 6784 N N   . SER E 5 191 ? 98.982  103.848 102.995 1.00 75.88  ? 138 SER R N   1 
ATOM 6785 C CA  . SER E 5 191 ? 100.135 103.158 102.437 1.00 73.23  ? 138 SER R CA  1 
ATOM 6786 C C   . SER E 5 191 ? 100.091 103.153 100.915 1.00 77.91  ? 138 SER R C   1 
ATOM 6787 O O   . SER E 5 191 ? 99.020  103.065 100.308 1.00 79.98  ? 138 SER R O   1 
ATOM 6788 C CB  . SER E 5 191 ? 100.199 101.722 102.958 1.00 73.49  ? 138 SER R CB  1 
ATOM 6789 O OG  . SER E 5 191 ? 99.079  100.972 102.523 1.00 74.82  ? 138 SER R OG  1 
ATOM 6790 N N   . LYS E 5 192 ? 101.270 103.240 100.301 1.00 75.56  ? 139 LYS R N   1 
ATOM 6791 C CA  . LYS E 5 192 ? 101.419 103.125 98.856  1.00 69.61  ? 139 LYS R CA  1 
ATOM 6792 C C   . LYS E 5 192 ? 102.068 101.794 98.506  1.00 69.82  ? 139 LYS R C   1 
ATOM 6793 O O   . LYS E 5 192 ? 101.510 101.003 97.741  1.00 70.59  ? 139 LYS R O   1 
ATOM 6794 C CB  . LYS E 5 192 ? 102.258 104.292 98.313  1.00 65.62  ? 139 LYS R CB  1 
ATOM 6795 C CG  . LYS E 5 192 ? 101.754 105.670 98.712  1.00 68.18  ? 139 LYS R CG  1 
ATOM 6796 C CD  . LYS E 5 192 ? 102.712 106.760 98.251  1.00 71.14  ? 139 LYS R CD  1 
ATOM 6797 C CE  . LYS E 5 192 ? 102.242 108.137 98.696  1.00 74.01  ? 139 LYS R CE  1 
ATOM 6798 N NZ  . LYS E 5 192 ? 103.179 109.214 98.267  1.00 66.36  ? 139 LYS R NZ  1 
ATOM 6799 N N   . LEU E 5 193 ? 103.249 101.535 99.057  1.00 68.63  ? 140 LEU R N   1 
ATOM 6800 C CA  . LEU E 5 193 ? 103.914 100.242 98.990  1.00 68.96  ? 140 LEU R CA  1 
ATOM 6801 C C   . LEU E 5 193 ? 104.284 99.835  100.404 1.00 70.85  ? 140 LEU R C   1 
ATOM 6802 O O   . LEU E 5 193 ? 104.874 100.627 101.146 1.00 67.03  ? 140 LEU R O   1 
ATOM 6803 C CB  . LEU E 5 193 ? 105.153 100.260 98.092  1.00 66.81  ? 140 LEU R CB  1 
ATOM 6804 C CG  . LEU E 5 193 ? 104.880 100.503 96.615  1.00 66.21  ? 140 LEU R CG  1 
ATOM 6805 C CD1 . LEU E 5 193 ? 106.176 100.645 95.844  1.00 65.36  ? 140 LEU R CD1 1 
ATOM 6806 C CD2 . LEU E 5 193 ? 104.094 99.311  96.113  1.00 67.82  ? 140 LEU R CD2 1 
ATOM 6807 N N   . HIS E 5 194 ? 103.914 98.616  100.783 1.00 89.94  ? 141 HIS R N   1 
ATOM 6808 C CA  . HIS E 5 194 ? 104.222 98.139  102.121 1.00 91.13  ? 141 HIS R CA  1 
ATOM 6809 C C   . HIS E 5 194 ? 105.732 98.090  102.304 1.00 91.86  ? 141 HIS R C   1 
ATOM 6810 O O   . HIS E 5 194 ? 106.462 97.625  101.423 1.00 95.59  ? 141 HIS R O   1 
ATOM 6811 C CB  . HIS E 5 194 ? 103.597 96.764  102.352 1.00 94.07  ? 141 HIS R CB  1 
ATOM 6812 C CG  . HIS E 5 194 ? 102.115 96.735  102.143 1.00 94.17  ? 141 HIS R CG  1 
ATOM 6813 N ND1 . HIS E 5 194 ? 101.540 96.481  100.916 1.00 91.63  ? 141 HIS R ND1 1 
ATOM 6814 C CD2 . HIS E 5 194 ? 101.089 96.938  103.003 1.00 91.55  ? 141 HIS R CD2 1 
ATOM 6815 C CE1 . HIS E 5 194 ? 100.224 96.524  101.031 1.00 90.84  ? 141 HIS R CE1 1 
ATOM 6816 N NE2 . HIS E 5 194 ? 99.925  96.800  102.288 1.00 94.11  ? 141 HIS R NE2 1 
ATOM 6817 N N   . TRP E 5 195 ? 106.193 98.586  103.452 1.00 83.86  ? 142 TRP R N   1 
ATOM 6818 C CA  . TRP E 5 195 ? 107.616 98.681  103.770 1.00 84.35  ? 142 TRP R CA  1 
ATOM 6819 C C   . TRP E 5 195 ? 108.346 99.537  102.733 1.00 83.27  ? 142 TRP R C   1 
ATOM 6820 O O   . TRP E 5 195 ? 109.386 99.152  102.195 1.00 87.30  ? 142 TRP R O   1 
ATOM 6821 C CB  . TRP E 5 195 ? 108.252 97.292  103.872 1.00 85.01  ? 142 TRP R CB  1 
ATOM 6822 C CG  . TRP E 5 195 ? 107.842 96.523  105.083 1.00 87.83  ? 142 TRP R CG  1 
ATOM 6823 C CD1 . TRP E 5 195 ? 108.089 96.848  106.382 1.00 89.57  ? 142 TRP R CD1 1 
ATOM 6824 C CD2 . TRP E 5 195 ? 107.127 95.281  105.108 1.00 86.65  ? 142 TRP R CD2 1 
ATOM 6825 N NE1 . TRP E 5 195 ? 107.562 95.893  107.218 1.00 89.63  ? 142 TRP R NE1 1 
ATOM 6826 C CE2 . TRP E 5 195 ? 106.967 94.919  106.460 1.00 90.29  ? 142 TRP R CE2 1 
ATOM 6827 C CE3 . TRP E 5 195 ? 106.603 94.444  104.118 1.00 79.66  ? 142 TRP R CE3 1 
ATOM 6828 C CZ2 . TRP E 5 195 ? 106.306 93.755  106.848 1.00 86.52  ? 142 TRP R CZ2 1 
ATOM 6829 C CZ3 . TRP E 5 195 ? 105.947 93.289  104.505 1.00 86.08  ? 142 TRP R CZ3 1 
ATOM 6830 C CH2 . TRP E 5 195 ? 105.804 92.956  105.858 1.00 86.84  ? 142 TRP R CH2 1 
ATOM 6831 N N   . CYS E 5 196 ? 107.789 100.718 102.457 1.00 73.19  ? 143 CYS R N   1 
ATOM 6832 C CA  . CYS E 5 196 ? 108.402 101.682 101.538 1.00 74.30  ? 143 CYS R CA  1 
ATOM 6833 C C   . CYS E 5 196 ? 108.276 103.084 102.129 1.00 77.80  ? 143 CYS R C   1 
ATOM 6834 O O   . CYS E 5 196 ? 107.215 103.708 102.034 1.00 79.04  ? 143 CYS R O   1 
ATOM 6835 C CB  . CYS E 5 196 ? 107.763 101.611 100.157 1.00 77.51  ? 143 CYS R CB  1 
ATOM 6836 S SG  . CYS E 5 196 ? 108.330 102.893 99.020  1.00 85.27  ? 143 CYS R SG  1 
ATOM 6837 N N   . ASN E 5 197 ? 109.365 103.569 102.730 1.00 87.44  ? 144 ASN R N   1 
ATOM 6838 C CA  . ASN E 5 197 ? 109.478 104.947 103.215 1.00 83.99  ? 144 ASN R CA  1 
ATOM 6839 C C   . ASN E 5 197 ? 108.349 105.294 104.187 1.00 83.14  ? 144 ASN R C   1 
ATOM 6840 O O   . ASN E 5 197 ? 107.704 106.339 104.085 1.00 86.77  ? 144 ASN R O   1 
ATOM 6841 C CB  . ASN E 5 197 ? 109.521 105.936 102.046 1.00 82.87  ? 144 ASN R CB  1 
ATOM 6842 C CG  . ASN E 5 197 ? 109.999 107.314 102.463 1.00 84.52  ? 144 ASN R CG  1 
ATOM 6843 O OD1 . ASN E 5 197 ? 111.200 107.569 102.545 1.00 85.33  ? 144 ASN R OD1 1 
ATOM 6844 N ND2 . ASN E 5 197 ? 109.057 108.212 102.729 1.00 87.14  ? 144 ASN R ND2 1 
ATOM 6845 N N   . ASN E 5 198 ? 108.114 104.399 105.143 1.00 68.08  ? 145 ASN R N   1 
ATOM 6846 C CA  . ASN E 5 198 ? 107.105 104.610 106.175 1.00 66.50  ? 145 ASN R CA  1 
ATOM 6847 C C   . ASN E 5 198 ? 107.629 104.150 107.528 1.00 70.26  ? 145 ASN R C   1 
ATOM 6848 O O   . ASN E 5 198 ? 106.927 103.475 108.287 1.00 74.72  ? 145 ASN R O   1 
ATOM 6849 C CB  . ASN E 5 198 ? 105.798 103.895 105.829 1.00 64.37  ? 145 ASN R CB  1 
ATOM 6850 C CG  . ASN E 5 198 ? 106.007 102.440 105.454 1.00 69.74  ? 145 ASN R CG  1 
ATOM 6851 O OD1 . ASN E 5 198 ? 107.092 101.887 105.637 1.00 69.12  ? 145 ASN R OD1 1 
ATOM 6852 N ND2 . ASN E 5 198 ? 104.963 101.811 104.927 1.00 78.02  ? 145 ASN R ND2 1 
ATOM 6853 N N   . VAL E 5 199 ? 108.878 104.504 107.843 1.00 64.66  ? 146 VAL R N   1 
ATOM 6854 C CA  . VAL E 5 199 ? 109.444 104.140 109.145 1.00 60.60  ? 146 VAL R CA  1 
ATOM 6855 C C   . VAL E 5 199 ? 108.633 104.712 110.303 1.00 62.83  ? 146 VAL R C   1 
ATOM 6856 O O   . VAL E 5 199 ? 108.366 103.971 111.264 1.00 67.88  ? 146 VAL R O   1 
ATOM 6857 C CB  . VAL E 5 199 ? 110.929 104.538 109.205 1.00 62.16  ? 146 VAL R CB  1 
ATOM 6858 C CG1 . VAL E 5 199 ? 111.536 104.137 110.540 1.00 58.82  ? 146 VAL R CG1 1 
ATOM 6859 C CG2 . VAL E 5 199 ? 111.691 103.910 108.051 1.00 65.96  ? 146 VAL R CG2 1 
ATOM 6860 N N   . PRO E 5 200 ? 108.225 105.988 110.299 1.00 69.95  ? 147 PRO R N   1 
ATOM 6861 C CA  . PRO E 5 200 ? 107.342 106.460 111.379 1.00 61.50  ? 147 PRO R CA  1 
ATOM 6862 C C   . PRO E 5 200 ? 106.024 105.713 111.444 1.00 64.81  ? 147 PRO R C   1 
ATOM 6863 O O   . PRO E 5 200 ? 105.473 105.533 112.536 1.00 67.65  ? 147 PRO R O   1 
ATOM 6864 C CB  . PRO E 5 200 ? 107.133 107.941 111.039 1.00 70.77  ? 147 PRO R CB  1 
ATOM 6865 C CG  . PRO E 5 200 ? 108.332 108.315 110.252 1.00 76.88  ? 147 PRO R CG  1 
ATOM 6866 C CD  . PRO E 5 200 ? 108.646 107.103 109.429 1.00 73.63  ? 147 PRO R CD  1 
ATOM 6867 N N   . ASP E 5 201 ? 105.500 105.274 110.297 1.00 71.82  ? 148 ASP R N   1 
ATOM 6868 C CA  . ASP E 5 201 ? 104.209 104.596 110.277 1.00 69.03  ? 148 ASP R CA  1 
ATOM 6869 C C   . ASP E 5 201 ? 104.296 103.172 110.814 1.00 65.68  ? 148 ASP R C   1 
ATOM 6870 O O   . ASP E 5 201 ? 103.313 102.658 111.360 1.00 67.02  ? 148 ASP R O   1 
ATOM 6871 C CB  . ASP E 5 201 ? 103.650 104.597 108.855 1.00 75.53  ? 148 ASP R CB  1 
ATOM 6872 C CG  . ASP E 5 201 ? 103.529 105.995 108.277 1.00 80.32  ? 148 ASP R CG  1 
ATOM 6873 O OD1 . ASP E 5 201 ? 104.576 106.617 107.998 1.00 78.10  ? 148 ASP R OD1 1 
ATOM 6874 O OD2 . ASP E 5 201 ? 102.389 106.471 108.102 1.00 82.46  ? 148 ASP R OD2 1 
ATOM 6875 N N   . ILE E 5 202 ? 105.449 102.518 110.666 1.00 62.46  ? 149 ILE R N   1 
ATOM 6876 C CA  . ILE E 5 202 ? 105.614 101.172 111.208 1.00 59.83  ? 149 ILE R CA  1 
ATOM 6877 C C   . ILE E 5 202 ? 105.593 101.188 112.732 1.00 64.19  ? 149 ILE R C   1 
ATOM 6878 O O   . ILE E 5 202 ? 104.943 100.348 113.365 1.00 67.24  ? 149 ILE R O   1 
ATOM 6879 C CB  . ILE E 5 202 ? 106.907 100.535 110.667 1.00 54.45  ? 149 ILE R CB  1 
ATOM 6880 C CG1 . ILE E 5 202 ? 106.835 100.388 109.148 1.00 59.56  ? 149 ILE R CG1 1 
ATOM 6881 C CG2 . ILE E 5 202 ? 107.157 99.189  111.322 1.00 57.47  ? 149 ILE R CG2 1 
ATOM 6882 C CD1 . ILE E 5 202 ? 108.054 99.733  108.539 1.00 63.05  ? 149 ILE R CD1 1 
ATOM 6883 N N   . PHE E 5 203 ? 106.299 102.140 113.345 1.00 44.65  ? 150 PHE R N   1 
ATOM 6884 C CA  . PHE E 5 203 ? 106.306 102.234 114.802 1.00 35.09  ? 150 PHE R CA  1 
ATOM 6885 C C   . PHE E 5 203 ? 104.938 102.619 115.353 1.00 37.10  ? 150 PHE R C   1 
ATOM 6886 O O   . PHE E 5 203 ? 104.502 102.080 116.376 1.00 49.10  ? 150 PHE R O   1 
ATOM 6887 C CB  . PHE E 5 203 ? 107.366 103.235 115.257 1.00 39.51  ? 150 PHE R CB  1 
ATOM 6888 C CG  . PHE E 5 203 ? 108.767 102.698 115.208 1.00 35.11  ? 150 PHE R CG  1 
ATOM 6889 C CD1 . PHE E 5 203 ? 109.203 101.777 116.146 1.00 30.26  ? 150 PHE R CD1 1 
ATOM 6890 C CD2 . PHE E 5 203 ? 109.648 103.113 114.225 1.00 47.39  ? 150 PHE R CD2 1 
ATOM 6891 C CE1 . PHE E 5 203 ? 110.491 101.282 116.104 1.00 34.84  ? 150 PHE R CE1 1 
ATOM 6892 C CE2 . PHE E 5 203 ? 110.937 102.621 114.179 1.00 45.18  ? 150 PHE R CE2 1 
ATOM 6893 C CZ  . PHE E 5 203 ? 111.359 101.705 115.119 1.00 39.37  ? 150 PHE R CZ  1 
ATOM 6894 N N   . ILE E 5 204 ? 104.242 103.545 114.688 1.00 43.51  ? 151 ILE R N   1 
ATOM 6895 C CA  . ILE E 5 204 ? 102.987 104.054 115.229 1.00 47.54  ? 151 ILE R CA  1 
ATOM 6896 C C   . ILE E 5 204 ? 101.856 103.038 115.114 1.00 54.17  ? 151 ILE R C   1 
ATOM 6897 O O   . ILE E 5 204 ? 100.859 103.144 115.838 1.00 62.09  ? 151 ILE R O   1 
ATOM 6898 C CB  . ILE E 5 204 ? 102.614 105.384 114.546 1.00 49.84  ? 151 ILE R CB  1 
ATOM 6899 C CG1 . ILE E 5 204 ? 101.571 106.141 115.372 1.00 54.22  ? 151 ILE R CG1 1 
ATOM 6900 C CG2 . ILE E 5 204 ? 102.105 105.142 113.144 1.00 55.88  ? 151 ILE R CG2 1 
ATOM 6901 C CD1 . ILE E 5 204 ? 101.956 106.327 116.822 1.00 57.58  ? 151 ILE R CD1 1 
ATOM 6902 N N   . ILE E 5 205 ? 101.981 102.045 114.232 1.00 57.36  ? 152 ILE R N   1 
ATOM 6903 C CA  . ILE E 5 205 ? 100.947 101.021 114.120 1.00 52.05  ? 152 ILE R CA  1 
ATOM 6904 C C   . ILE E 5 205 ? 101.239 99.809  114.999 1.00 58.15  ? 152 ILE R C   1 
ATOM 6905 O O   . ILE E 5 205 ? 100.302 99.097  115.388 1.00 67.33  ? 152 ILE R O   1 
ATOM 6906 C CB  . ILE E 5 205 ? 100.764 100.588 112.652 1.00 56.06  ? 152 ILE R CB  1 
ATOM 6907 C CG1 . ILE E 5 205 ? 99.465  99.795  112.478 1.00 57.16  ? 152 ILE R CG1 1 
ATOM 6908 C CG2 . ILE E 5 205 ? 101.953 99.767  112.177 1.00 61.21  ? 152 ILE R CG2 1 
ATOM 6909 C CD1 . ILE E 5 205 ? 99.237  99.296  111.066 1.00 64.08  ? 152 ILE R CD1 1 
ATOM 6910 N N   . ASN E 5 206 ? 102.506 99.564  115.340 1.00 58.85  ? 153 ASN R N   1 
ATOM 6911 C CA  . ASN E 5 206 ? 102.837 98.510  116.293 1.00 63.96  ? 153 ASN R CA  1 
ATOM 6912 C C   . ASN E 5 206 ? 102.524 98.929  117.724 1.00 60.21  ? 153 ASN R C   1 
ATOM 6913 O O   . ASN E 5 206 ? 102.092 98.101  118.534 1.00 62.10  ? 153 ASN R O   1 
ATOM 6914 C CB  . ASN E 5 206 ? 104.310 98.123  116.163 1.00 53.91  ? 153 ASN R CB  1 
ATOM 6915 C CG  . ASN E 5 206 ? 104.594 97.329  114.905 1.00 53.07  ? 153 ASN R CG  1 
ATOM 6916 O OD1 . ASN E 5 206 ? 104.670 96.101  114.937 1.00 66.80  ? 153 ASN R OD1 1 
ATOM 6917 N ND2 . ASN E 5 206 ? 104.748 98.027  113.786 1.00 53.08  ? 153 ASN R ND2 1 
ATOM 6918 N N   . LEU E 5 207 ? 102.734 100.206 118.053 1.00 48.71  ? 154 LEU R N   1 
ATOM 6919 C CA  . LEU E 5 207 ? 102.365 100.697 119.376 1.00 50.04  ? 154 LEU R CA  1 
ATOM 6920 C C   . LEU E 5 207 ? 100.861 100.629 119.600 1.00 59.81  ? 154 LEU R C   1 
ATOM 6921 O O   . LEU E 5 207 ? 100.410 100.435 120.735 1.00 73.36  ? 154 LEU R O   1 
ATOM 6922 C CB  . LEU E 5 207 ? 102.864 102.131 119.559 1.00 58.15  ? 154 LEU R CB  1 
ATOM 6923 C CG  . LEU E 5 207 ? 102.653 102.775 120.930 1.00 57.44  ? 154 LEU R CG  1 
ATOM 6924 C CD1 . LEU E 5 207 ? 103.393 102.001 122.007 1.00 63.67  ? 154 LEU R CD1 1 
ATOM 6925 C CD2 . LEU E 5 207 ? 103.095 104.229 120.911 1.00 52.04  ? 154 LEU R CD2 1 
ATOM 6926 N N   . SER E 5 208 ? 100.070 100.781 118.538 1.00 53.89  ? 155 SER R N   1 
ATOM 6927 C CA  . SER E 5 208 ? 98.622  100.689 118.675 1.00 60.33  ? 155 SER R CA  1 
ATOM 6928 C C   . SER E 5 208 ? 98.151  99.244  118.794 1.00 69.33  ? 155 SER R C   1 
ATOM 6929 O O   . SER E 5 208 ? 97.128  98.984  119.438 1.00 77.10  ? 155 SER R O   1 
ATOM 6930 C CB  . SER E 5 208 ? 97.942  101.376 117.491 1.00 63.19  ? 155 SER R CB  1 
ATOM 6931 O OG  . SER E 5 208 ? 98.265  102.755 117.456 1.00 75.66  ? 155 SER R OG  1 
ATOM 6932 N N   . VAL E 5 209 ? 98.874  98.300  118.187 1.00 60.73  ? 156 VAL R N   1 
ATOM 6933 C CA  . VAL E 5 209 ? 98.518  96.890  118.322 1.00 57.50  ? 156 VAL R CA  1 
ATOM 6934 C C   . VAL E 5 209 ? 98.767  96.410  119.747 1.00 62.78  ? 156 VAL R C   1 
ATOM 6935 O O   . VAL E 5 209 ? 97.929  95.719  120.339 1.00 61.44  ? 156 VAL R O   1 
ATOM 6936 C CB  . VAL E 5 209 ? 99.292  96.043  117.294 1.00 56.37  ? 156 VAL R CB  1 
ATOM 6937 C CG1 . VAL E 5 209 ? 99.200  94.563  117.637 1.00 58.98  ? 156 VAL R CG1 1 
ATOM 6938 C CG2 . VAL E 5 209 ? 98.763  96.291  115.890 1.00 64.66  ? 156 VAL R CG2 1 
ATOM 6939 N N   . VAL E 5 210 ? 99.914  96.774  120.324 1.00 67.09  ? 157 VAL R N   1 
ATOM 6940 C CA  . VAL E 5 210 ? 100.224 96.351  121.686 1.00 65.88  ? 157 VAL R CA  1 
ATOM 6941 C C   . VAL E 5 210 ? 99.282  97.018  122.679 1.00 64.42  ? 157 VAL R C   1 
ATOM 6942 O O   . VAL E 5 210 ? 98.815  96.385  123.634 1.00 72.87  ? 157 VAL R O   1 
ATOM 6943 C CB  . VAL E 5 210 ? 101.697 96.648  122.014 1.00 57.36  ? 157 VAL R CB  1 
ATOM 6944 C CG1 . VAL E 5 210 ? 102.037 96.137  123.399 1.00 59.83  ? 157 VAL R CG1 1 
ATOM 6945 C CG2 . VAL E 5 210 ? 102.600 96.021  120.975 1.00 62.68  ? 157 VAL R CG2 1 
ATOM 6946 N N   . ASP E 5 211 ? 98.991  98.305  122.474 1.00 69.84  ? 158 ASP R N   1 
ATOM 6947 C CA  . ASP E 5 211 ? 98.035  98.990  123.336 1.00 80.26  ? 158 ASP R CA  1 
ATOM 6948 C C   . ASP E 5 211 ? 96.651  98.369  123.223 1.00 83.18  ? 158 ASP R C   1 
ATOM 6949 O O   . ASP E 5 211 ? 95.913  98.312  124.213 1.00 85.89  ? 158 ASP R O   1 
ATOM 6950 C CB  . ASP E 5 211 ? 97.981  100.477 122.988 1.00 83.79  ? 158 ASP R CB  1 
ATOM 6951 C CG  . ASP E 5 211 ? 99.180  101.242 123.511 1.00 86.34  ? 158 ASP R CG  1 
ATOM 6952 O OD1 . ASP E 5 211 ? 100.022 100.628 124.197 1.00 79.85  ? 158 ASP R OD1 1 
ATOM 6953 O OD2 . ASP E 5 211 ? 99.278  102.457 123.239 1.00 91.43  ? 158 ASP R OD2 1 
ATOM 6954 N N   . LEU E 5 212 ? 96.282  97.901  122.029 1.00 79.11  ? 159 LEU R N   1 
ATOM 6955 C CA  . LEU E 5 212 ? 95.022  97.183  121.877 1.00 80.10  ? 159 LEU R CA  1 
ATOM 6956 C C   . LEU E 5 212 ? 95.050  95.864  122.637 1.00 85.17  ? 159 LEU R C   1 
ATOM 6957 O O   . LEU E 5 212 ? 94.052  95.472  123.251 1.00 89.47  ? 159 LEU R O   1 
ATOM 6958 C CB  . LEU E 5 212 ? 94.734  96.948  120.394 1.00 79.34  ? 159 LEU R CB  1 
ATOM 6959 C CG  . LEU E 5 212 ? 93.330  96.472  120.021 1.00 84.75  ? 159 LEU R CG  1 
ATOM 6960 C CD1 . LEU E 5 212 ? 92.292  97.487  120.459 1.00 85.41  ? 159 LEU R CD1 1 
ATOM 6961 C CD2 . LEU E 5 212 ? 93.231  96.212  118.526 1.00 84.23  ? 159 LEU R CD2 1 
ATOM 6962 N N   . LEU E 5 213 ? 96.188  95.164  122.605 1.00 77.40  ? 160 LEU R N   1 
ATOM 6963 C CA  . LEU E 5 213 ? 96.329  93.936  123.380 1.00 79.92  ? 160 LEU R CA  1 
ATOM 6964 C C   . LEU E 5 213 ? 96.252  94.214  124.877 1.00 80.98  ? 160 LEU R C   1 
ATOM 6965 O O   . LEU E 5 213 ? 95.674  93.425  125.634 1.00 75.56  ? 160 LEU R O   1 
ATOM 6966 C CB  . LEU E 5 213 ? 97.648  93.247  123.030 1.00 74.71  ? 160 LEU R CB  1 
ATOM 6967 C CG  . LEU E 5 213 ? 97.755  92.673  121.616 1.00 78.04  ? 160 LEU R CG  1 
ATOM 6968 C CD1 . LEU E 5 213 ? 99.109  92.014  121.399 1.00 76.84  ? 160 LEU R CD1 1 
ATOM 6969 C CD2 . LEU E 5 213 ? 96.629  91.685  121.354 1.00 77.35  ? 160 LEU R CD2 1 
ATOM 6970 N N   . PHE E 5 214 ? 96.841  95.327  125.323 1.00 81.69  ? 161 PHE R N   1 
ATOM 6971 C CA  . PHE E 5 214 ? 96.837  95.662  126.744 1.00 77.24  ? 161 PHE R CA  1 
ATOM 6972 C C   . PHE E 5 214 ? 95.432  95.950  127.258 1.00 83.96  ? 161 PHE R C   1 
ATOM 6973 O O   . PHE E 5 214 ? 95.163  95.777  128.452 1.00 91.97  ? 161 PHE R O   1 
ATOM 6974 C CB  . PHE E 5 214 ? 97.758  96.856  126.998 1.00 78.61  ? 161 PHE R CB  1 
ATOM 6975 C CG  . PHE E 5 214 ? 98.126  97.045  128.441 1.00 79.99  ? 161 PHE R CG  1 
ATOM 6976 C CD1 . PHE E 5 214 ? 98.815  96.058  129.125 1.00 82.50  ? 161 PHE R CD1 1 
ATOM 6977 C CD2 . PHE E 5 214 ? 97.807  98.216  129.108 1.00 83.05  ? 161 PHE R CD2 1 
ATOM 6978 C CE1 . PHE E 5 214 ? 99.162  96.226  130.450 1.00 84.26  ? 161 PHE R CE1 1 
ATOM 6979 C CE2 . PHE E 5 214 ? 98.158  98.391  130.433 1.00 85.01  ? 161 PHE R CE2 1 
ATOM 6980 C CZ  . PHE E 5 214 ? 98.834  97.394  131.105 1.00 83.95  ? 161 PHE R CZ  1 
ATOM 6981 N N   . LEU E 5 215 ? 94.529  96.385  126.380 1.00 94.45  ? 162 LEU R N   1 
ATOM 6982 C CA  . LEU E 5 215 ? 93.155  96.678  126.769 1.00 97.84  ? 162 LEU R CA  1 
ATOM 6983 C C   . LEU E 5 215 ? 92.212  95.505  126.543 1.00 101.36 ? 162 LEU R C   1 
ATOM 6984 O O   . LEU E 5 215 ? 91.246  95.344  127.298 1.00 106.29 ? 162 LEU R O   1 
ATOM 6985 C CB  . LEU E 5 215 ? 92.646  97.906  126.010 1.00 97.04  ? 162 LEU R CB  1 
ATOM 6986 C CG  . LEU E 5 215 ? 93.516  99.155  126.162 1.00 101.62 ? 162 LEU R CG  1 
ATOM 6987 C CD1 . LEU E 5 215 ? 92.880  100.340 125.467 1.00 104.07 ? 162 LEU R CD1 1 
ATOM 6988 C CD2 . LEU E 5 215 ? 93.774  99.465  127.629 1.00 101.06 ? 162 LEU R CD2 1 
ATOM 6989 N N   . LEU E 5 216 ? 92.464  94.685  125.519 1.00 101.56 ? 163 LEU R N   1 
ATOM 6990 C CA  . LEU E 5 216 ? 91.646  93.494  125.309 1.00 103.68 ? 163 LEU R CA  1 
ATOM 6991 C C   . LEU E 5 216 ? 91.795  92.513  126.465 1.00 105.91 ? 163 LEU R C   1 
ATOM 6992 O O   . LEU E 5 216 ? 90.822  91.867  126.870 1.00 108.32 ? 163 LEU R O   1 
ATOM 6993 C CB  . LEU E 5 216 ? 92.015  92.825  123.985 1.00 104.37 ? 163 LEU R CB  1 
ATOM 6994 C CG  . LEU E 5 216 ? 91.541  93.521  122.708 1.00 106.38 ? 163 LEU R CG  1 
ATOM 6995 C CD1 . LEU E 5 216 ? 91.950  92.724  121.479 1.00 105.37 ? 163 LEU R CD1 1 
ATOM 6996 C CD2 . LEU E 5 216 ? 90.034  93.732  122.735 1.00 105.30 ? 163 LEU R CD2 1 
ATOM 6997 N N   . GLY E 5 217 ? 93.005  92.381  127.004 1.00 108.55 ? 164 GLY R N   1 
ATOM 6998 C CA  . GLY E 5 217 ? 93.220  91.527  128.152 1.00 108.98 ? 164 GLY R CA  1 
ATOM 6999 C C   . GLY E 5 217 ? 92.911  92.154  129.491 1.00 106.65 ? 164 GLY R C   1 
ATOM 7000 O O   . GLY E 5 217 ? 93.045  91.487  130.521 1.00 105.51 ? 164 GLY R O   1 
ATOM 7001 N N   . MET E 5 218 ? 92.509  93.426  129.510 1.00 115.21 ? 165 MET R N   1 
ATOM 7002 C CA  . MET E 5 218 ? 92.178  94.083  130.774 1.00 116.81 ? 165 MET R CA  1 
ATOM 7003 C C   . MET E 5 218 ? 90.995  93.441  131.490 1.00 119.89 ? 165 MET R C   1 
ATOM 7004 O O   . MET E 5 218 ? 91.114  93.168  132.698 1.00 119.43 ? 165 MET R O   1 
ATOM 7005 C CB  . MET E 5 218 ? 91.942  95.579  130.539 1.00 115.71 ? 165 MET R CB  1 
ATOM 7006 C CG  . MET E 5 218 ? 91.459  96.315  131.780 1.00 119.97 ? 165 MET R CG  1 
ATOM 7007 S SD  . MET E 5 218 ? 90.458  97.764  131.406 1.00 124.16 ? 165 MET R SD  1 
ATOM 7008 C CE  . MET E 5 218 ? 91.644  98.760  130.510 1.00 118.27 ? 165 MET R CE  1 
ATOM 7009 N N   . PRO E 5 219 ? 89.845  93.185  130.850 1.00 124.68 ? 166 PRO R N   1 
ATOM 7010 C CA  . PRO E 5 219 ? 88.720  92.602  131.602 1.00 125.29 ? 166 PRO R CA  1 
ATOM 7011 C C   . PRO E 5 219 ? 89.020  91.226  132.164 1.00 126.08 ? 166 PRO R C   1 
ATOM 7012 O O   . PRO E 5 219 ? 88.377  90.815  133.137 1.00 125.41 ? 166 PRO R O   1 
ATOM 7013 C CB  . PRO E 5 219 ? 87.588  92.554  130.566 1.00 124.88 ? 166 PRO R CB  1 
ATOM 7014 C CG  . PRO E 5 219 ? 88.280  92.540  129.254 1.00 123.12 ? 166 PRO R CG  1 
ATOM 7015 C CD  . PRO E 5 219 ? 89.480  93.416  129.440 1.00 121.38 ? 166 PRO R CD  1 
ATOM 7016 N N   . PHE E 5 220 ? 89.977  90.502  131.585 1.00 127.67 ? 167 PHE R N   1 
ATOM 7017 C CA  . PHE E 5 220 ? 90.383  89.207  132.110 1.00 126.98 ? 167 PHE R CA  1 
ATOM 7018 C C   . PHE E 5 220 ? 91.273  89.337  133.338 1.00 127.97 ? 167 PHE R C   1 
ATOM 7019 O O   . PHE E 5 220 ? 91.518  88.335  134.018 1.00 129.87 ? 167 PHE R O   1 
ATOM 7020 C CB  . PHE E 5 220 ? 91.114  88.402  131.032 1.00 125.12 ? 167 PHE R CB  1 
ATOM 7021 C CG  . PHE E 5 220 ? 90.282  88.122  129.814 1.00 127.22 ? 167 PHE R CG  1 
ATOM 7022 C CD1 . PHE E 5 220 ? 89.424  87.036  129.779 1.00 127.39 ? 167 PHE R CD1 1 
ATOM 7023 C CD2 . PHE E 5 220 ? 90.365  88.941  128.699 1.00 128.17 ? 167 PHE R CD2 1 
ATOM 7024 C CE1 . PHE E 5 220 ? 88.658  86.775  128.658 1.00 127.83 ? 167 PHE R CE1 1 
ATOM 7025 C CE2 . PHE E 5 220 ? 89.603  88.685  127.575 1.00 127.37 ? 167 PHE R CE2 1 
ATOM 7026 C CZ  . PHE E 5 220 ? 88.748  87.600  127.555 1.00 126.86 ? 167 PHE R CZ  1 
ATOM 7027 N N   . MET E 5 221 ? 91.756  90.547  133.632 1.00 129.95 ? 168 MET R N   1 
ATOM 7028 C CA  . MET E 5 221 ? 92.600  90.804  134.788 1.00 130.05 ? 168 MET R CA  1 
ATOM 7029 C C   . MET E 5 221 ? 91.894  91.542  135.915 1.00 130.01 ? 168 MET R C   1 
ATOM 7030 O O   . MET E 5 221 ? 92.340  91.446  137.062 1.00 130.49 ? 168 MET R O   1 
ATOM 7031 C CB  . MET E 5 221 ? 93.838  91.613  134.372 1.00 128.65 ? 168 MET R CB  1 
ATOM 7032 C CG  . MET E 5 221 ? 94.925  90.788  133.709 1.00 130.60 ? 168 MET R CG  1 
ATOM 7033 S SD  . MET E 5 221 ? 95.595  89.532  134.813 1.00 138.67 ? 168 MET R SD  1 
ATOM 7034 C CE  . MET E 5 221 ? 96.157  90.551  136.175 1.00 129.92 ? 168 MET R CE  1 
ATOM 7035 N N   . ILE E 5 222 ? 90.810  92.267  135.627 1.00 134.24 ? 169 ILE R N   1 
ATOM 7036 C CA  . ILE E 5 222 ? 90.151  93.084  136.641 1.00 137.08 ? 169 ILE R CA  1 
ATOM 7037 C C   . ILE E 5 222 ? 88.905  92.428  137.217 1.00 136.60 ? 169 ILE R C   1 
ATOM 7038 O O   . ILE E 5 222 ? 88.346  92.950  138.196 1.00 135.82 ? 169 ILE R O   1 
ATOM 7039 C CB  . ILE E 5 222 ? 89.776  94.473  136.081 1.00 136.16 ? 169 ILE R CB  1 
ATOM 7040 C CG1 . ILE E 5 222 ? 88.861  94.317  134.864 1.00 133.25 ? 169 ILE R CG1 1 
ATOM 7041 C CG2 . ILE E 5 222 ? 91.027  95.261  135.728 1.00 135.82 ? 169 ILE R CG2 1 
ATOM 7042 C CD1 . ILE E 5 222 ? 88.465  95.625  134.221 1.00 135.46 ? 169 ILE R CD1 1 
ATOM 7043 N N   . HIS E 5 223 ? 88.454  91.304  136.658 1.00 144.15 ? 170 HIS R N   1 
ATOM 7044 C CA  . HIS E 5 223 ? 87.275  90.647  137.205 1.00 145.50 ? 170 HIS R CA  1 
ATOM 7045 C C   . HIS E 5 223 ? 87.548  90.014  138.561 1.00 146.32 ? 170 HIS R C   1 
ATOM 7046 O O   . HIS E 5 223 ? 86.597  89.661  139.267 1.00 147.12 ? 170 HIS R O   1 
ATOM 7047 C CB  . HIS E 5 223 ? 86.760  89.587  136.229 1.00 146.32 ? 170 HIS R CB  1 
ATOM 7048 C CG  . HIS E 5 223 ? 87.426  88.254  136.378 1.00 148.12 ? 170 HIS R CG  1 
ATOM 7049 N ND1 . HIS E 5 223 ? 88.626  87.950  135.773 1.00 147.97 ? 170 HIS R ND1 1 
ATOM 7050 C CD2 . HIS E 5 223 ? 87.055  87.144  137.059 1.00 147.51 ? 170 HIS R CD2 1 
ATOM 7051 C CE1 . HIS E 5 223 ? 88.969  86.711  136.078 1.00 146.46 ? 170 HIS R CE1 1 
ATOM 7052 N NE2 . HIS E 5 223 ? 88.033  86.200  136.856 1.00 146.48 ? 170 HIS R NE2 1 
ATOM 7053 N N   . GLN E 5 224 ? 88.817  89.863  138.935 1.00 144.34 ? 171 GLN R N   1 
ATOM 7054 C CA  . GLN E 5 224 ? 89.212  89.415  140.261 1.00 144.66 ? 171 GLN R CA  1 
ATOM 7055 C C   . GLN E 5 224 ? 89.445  90.576  141.217 1.00 143.74 ? 171 GLN R C   1 
ATOM 7056 O O   . GLN E 5 224 ? 89.963  90.366  142.318 1.00 142.82 ? 171 GLN R O   1 
ATOM 7057 C CB  . GLN E 5 224 ? 90.474  88.553  140.167 1.00 146.81 ? 171 GLN R CB  1 
ATOM 7058 C CG  . GLN E 5 224 ? 91.675  89.284  139.585 1.00 145.64 ? 171 GLN R CG  1 
ATOM 7059 C CD  . GLN E 5 224 ? 92.926  88.428  139.563 1.00 145.18 ? 171 GLN R CD  1 
ATOM 7060 O OE1 . GLN E 5 224 ? 92.918  87.283  140.014 1.00 147.09 ? 171 GLN R OE1 1 
ATOM 7061 N NE2 . GLN E 5 224 ? 94.012  88.982  139.035 1.00 142.86 ? 171 GLN R NE2 1 
ATOM 7062 N N   . LEU E 5 225 ? 89.097  91.797  140.810 1.00 145.16 ? 172 LEU R N   1 
ATOM 7063 C CA  . LEU E 5 225 ? 89.230  92.971  141.656 1.00 147.01 ? 172 LEU R CA  1 
ATOM 7064 C C   . LEU E 5 225 ? 87.907  93.630  142.016 1.00 146.85 ? 172 LEU R C   1 
ATOM 7065 O O   . LEU E 5 225 ? 87.883  94.454  142.937 1.00 146.35 ? 172 LEU R O   1 
ATOM 7066 C CB  . LEU E 5 225 ? 90.134  94.016  140.983 1.00 146.14 ? 172 LEU R CB  1 
ATOM 7067 C CG  . LEU E 5 225 ? 91.501  93.528  140.499 1.00 145.97 ? 172 LEU R CG  1 
ATOM 7068 C CD1 . LEU E 5 225 ? 92.144  94.559  139.583 1.00 145.91 ? 172 LEU R CD1 1 
ATOM 7069 C CD2 . LEU E 5 225 ? 92.409  93.213  141.678 1.00 145.89 ? 172 LEU R CD2 1 
ATOM 7070 N N   . MET E 5 226 ? 86.814  93.305  141.327 1.00 148.93 ? 173 MET R N   1 
ATOM 7071 C CA  . MET E 5 226 ? 85.563  94.036  141.480 1.00 148.48 ? 173 MET R CA  1 
ATOM 7072 C C   . MET E 5 226 ? 84.442  93.210  142.092 1.00 149.41 ? 173 MET R C   1 
ATOM 7073 O O   . MET E 5 226 ? 83.858  93.618  143.100 1.00 149.65 ? 173 MET R O   1 
ATOM 7074 C CB  . MET E 5 226 ? 85.113  94.572  140.114 1.00 147.97 ? 173 MET R CB  1 
ATOM 7075 C CG  . MET E 5 226 ? 86.146  95.436  139.411 1.00 148.69 ? 173 MET R CG  1 
ATOM 7076 S SD  . MET E 5 226 ? 85.680  95.818  137.712 1.00 152.90 ? 173 MET R SD  1 
ATOM 7077 C CE  . MET E 5 226 ? 85.601  94.177  137.000 1.00 149.00 ? 173 MET R CE  1 
ATOM 7078 N N   . GLY E 5 227 ? 84.116  92.057  141.510 1.00 148.07 ? 174 GLY R N   1 
ATOM 7079 C CA  . GLY E 5 227 ? 82.964  91.307  141.974 1.00 147.85 ? 174 GLY R CA  1 
ATOM 7080 C C   . GLY E 5 227 ? 83.144  90.613  143.308 1.00 148.54 ? 174 GLY R C   1 
ATOM 7081 O O   . GLY E 5 227 ? 82.497  90.976  144.295 1.00 147.63 ? 174 GLY R O   1 
ATOM 7082 N N   . ASN E 5 228 ? 84.023  89.610  143.352 1.00 151.12 ? 175 ASN R N   1 
ATOM 7083 C CA  . ASN E 5 228 ? 84.273  88.876  144.583 1.00 150.34 ? 175 ASN R CA  1 
ATOM 7084 C C   . ASN E 5 228 ? 85.736  88.512  144.788 1.00 151.86 ? 175 ASN R C   1 
ATOM 7085 O O   . ASN E 5 228 ? 86.049  87.830  145.769 1.00 151.75 ? 175 ASN R O   1 
ATOM 7086 C CB  . ASN E 5 228 ? 83.424  87.594  144.623 1.00 148.58 ? 175 ASN R CB  1 
ATOM 7087 N N   . GLY E 5 229 ? 86.635  88.942  143.910 1.00 149.09 ? 176 GLY R N   1 
ATOM 7088 C CA  . GLY E 5 229 ? 88.041  88.606  144.046 1.00 146.69 ? 176 GLY R CA  1 
ATOM 7089 C C   . GLY E 5 229 ? 88.345  87.137  143.846 1.00 147.09 ? 176 GLY R C   1 
ATOM 7090 O O   . GLY E 5 229 ? 89.166  86.573  144.581 1.00 145.99 ? 176 GLY R O   1 
ATOM 7091 N N   . VAL E 5 230 ? 87.703  86.500  142.867 1.00 149.62 ? 177 VAL R N   1 
ATOM 7092 C CA  . VAL E 5 230 ? 87.849  85.070  142.627 1.00 150.21 ? 177 VAL R CA  1 
ATOM 7093 C C   . VAL E 5 230 ? 88.222  84.863  141.167 1.00 149.07 ? 177 VAL R C   1 
ATOM 7094 O O   . VAL E 5 230 ? 87.658  85.508  140.276 1.00 148.52 ? 177 VAL R O   1 
ATOM 7095 C CB  . VAL E 5 230 ? 86.556  84.296  142.965 1.00 149.94 ? 177 VAL R CB  1 
ATOM 7096 C CG1 . VAL E 5 230 ? 86.805  82.795  142.926 1.00 148.59 ? 177 VAL R CG1 1 
ATOM 7097 C CG2 . VAL E 5 230 ? 86.009  84.723  144.319 1.00 149.17 ? 177 VAL R CG2 1 
ATOM 7098 N N   . TRP E 5 231 ? 89.173  83.965  140.920 1.00 140.76 ? 178 TRP R N   1 
ATOM 7099 C CA  . TRP E 5 231 ? 89.518  83.568  139.562 1.00 140.33 ? 178 TRP R CA  1 
ATOM 7100 C C   . TRP E 5 231 ? 88.592  82.449  139.100 1.00 139.50 ? 178 TRP R C   1 
ATOM 7101 O O   . TRP E 5 231 ? 88.453  81.430  139.783 1.00 137.42 ? 178 TRP R O   1 
ATOM 7102 C CB  . TRP E 5 231 ? 90.978  83.120  139.489 1.00 140.17 ? 178 TRP R CB  1 
ATOM 7103 C CG  . TRP E 5 231 ? 91.425  82.794  138.105 1.00 140.08 ? 178 TRP R CG  1 
ATOM 7104 C CD1 . TRP E 5 231 ? 91.507  81.558  137.537 1.00 139.90 ? 178 TRP R CD1 1 
ATOM 7105 C CD2 . TRP E 5 231 ? 91.841  83.726  137.102 1.00 139.27 ? 178 TRP R CD2 1 
ATOM 7106 N NE1 . TRP E 5 231 ? 91.957  81.661  136.243 1.00 140.28 ? 178 TRP R NE1 1 
ATOM 7107 C CE2 . TRP E 5 231 ? 92.168  82.983  135.951 1.00 139.66 ? 178 TRP R CE2 1 
ATOM 7108 C CE3 . TRP E 5 231 ? 91.971  85.117  137.066 1.00 138.53 ? 178 TRP R CE3 1 
ATOM 7109 C CZ2 . TRP E 5 231 ? 92.614  83.585  134.778 1.00 140.14 ? 178 TRP R CZ2 1 
ATOM 7110 C CZ3 . TRP E 5 231 ? 92.416  85.712  135.902 1.00 139.69 ? 178 TRP R CZ3 1 
ATOM 7111 C CH2 . TRP E 5 231 ? 92.733  84.947  134.774 1.00 139.84 ? 178 TRP R CH2 1 
ATOM 7112 N N   . HIS E 5 232 ? 87.959  82.642  137.943 1.00 138.83 ? 179 HIS R N   1 
ATOM 7113 C CA  . HIS E 5 232 ? 86.967  81.702  137.434 1.00 138.08 ? 179 HIS R CA  1 
ATOM 7114 C C   . HIS E 5 232 ? 87.447  80.935  136.207 1.00 138.53 ? 179 HIS R C   1 
ATOM 7115 O O   . HIS E 5 232 ? 86.666  80.182  135.617 1.00 140.02 ? 179 HIS R O   1 
ATOM 7116 C CB  . HIS E 5 232 ? 85.663  82.436  137.110 1.00 137.93 ? 179 HIS R CB  1 
ATOM 7117 C CG  . HIS E 5 232 ? 85.137  83.263  138.242 1.00 138.76 ? 179 HIS R CG  1 
ATOM 7118 N ND1 . HIS E 5 232 ? 84.384  82.730  139.266 1.00 138.98 ? 179 HIS R ND1 1 
ATOM 7119 C CD2 . HIS E 5 232 ? 85.253  84.586  138.509 1.00 139.03 ? 179 HIS R CD2 1 
ATOM 7120 C CE1 . HIS E 5 232 ? 84.060  83.689  140.116 1.00 139.19 ? 179 HIS R CE1 1 
ATOM 7121 N NE2 . HIS E 5 232 ? 84.575  84.824  139.680 1.00 138.06 ? 179 HIS R NE2 1 
ATOM 7122 N N   . PHE E 5 233 ? 88.707  81.103  135.808 1.00 138.39 ? 180 PHE R N   1 
ATOM 7123 C CA  . PHE E 5 233 ? 89.209  80.550  134.557 1.00 138.87 ? 180 PHE R CA  1 
ATOM 7124 C C   . PHE E 5 233 ? 90.204  79.411  134.736 1.00 139.27 ? 180 PHE R C   1 
ATOM 7125 O O   . PHE E 5 233 ? 90.677  78.863  133.735 1.00 138.43 ? 180 PHE R O   1 
ATOM 7126 C CB  . PHE E 5 233 ? 89.841  81.658  133.706 1.00 138.74 ? 180 PHE R CB  1 
ATOM 7127 C CG  . PHE E 5 233 ? 88.871  82.726  133.285 1.00 139.23 ? 180 PHE R CG  1 
ATOM 7128 C CD1 . PHE E 5 233 ? 87.530  82.429  133.107 1.00 138.98 ? 180 PHE R CD1 1 
ATOM 7129 C CD2 . PHE E 5 233 ? 89.300  84.025  133.068 1.00 139.45 ? 180 PHE R CD2 1 
ATOM 7130 C CE1 . PHE E 5 233 ? 86.635  83.407  132.719 1.00 139.73 ? 180 PHE R CE1 1 
ATOM 7131 C CE2 . PHE E 5 233 ? 88.409  85.007  132.680 1.00 139.12 ? 180 PHE R CE2 1 
ATOM 7132 C CZ  . PHE E 5 233 ? 87.075  84.698  132.506 1.00 139.90 ? 180 PHE R CZ  1 
ATOM 7133 N N   . GLY E 5 234 ? 90.538  79.037  135.967 1.00 136.83 ? 181 GLY R N   1 
ATOM 7134 C CA  . GLY E 5 234 ? 91.432  77.923  136.197 1.00 135.77 ? 181 GLY R CA  1 
ATOM 7135 C C   . GLY E 5 234 ? 92.896  78.323  136.136 1.00 134.79 ? 181 GLY R C   1 
ATOM 7136 O O   . GLY E 5 234 ? 93.264  79.450  135.802 1.00 135.84 ? 181 GLY R O   1 
ATOM 7137 N N   . GLU E 5 235 ? 93.753  77.357  136.477 1.00 133.84 ? 182 GLU R N   1 
ATOM 7138 C CA  . GLU E 5 235 ? 95.182  77.618  136.607 1.00 134.13 ? 182 GLU R CA  1 
ATOM 7139 C C   . GLU E 5 235 ? 95.879  77.767  135.260 1.00 134.50 ? 182 GLU R C   1 
ATOM 7140 O O   . GLU E 5 235 ? 96.888  78.475  135.167 1.00 136.84 ? 182 GLU R O   1 
ATOM 7141 C CB  . GLU E 5 235 ? 95.844  76.498  137.412 1.00 136.34 ? 182 GLU R CB  1 
ATOM 7142 C CG  . GLU E 5 235 ? 97.300  76.756  137.768 1.00 136.10 ? 182 GLU R CG  1 
ATOM 7143 C CD  . GLU E 5 235 ? 97.923  75.610  138.539 1.00 138.20 ? 182 GLU R CD  1 
ATOM 7144 O OE1 . GLU E 5 235 ? 97.223  74.604  138.779 1.00 139.19 ? 182 GLU R OE1 1 
ATOM 7145 O OE2 . GLU E 5 235 ? 99.112  75.716  138.906 1.00 136.89 ? 182 GLU R OE2 1 
ATOM 7146 N N   . THR E 5 236 ? 95.363  77.127  134.209 1.00 122.03 ? 183 THR R N   1 
ATOM 7147 C CA  . THR E 5 236 ? 95.990  77.247  132.895 1.00 123.58 ? 183 THR R CA  1 
ATOM 7148 C C   . THR E 5 236 ? 95.815  78.650  132.327 1.00 122.27 ? 183 THR R C   1 
ATOM 7149 O O   . THR E 5 236 ? 96.768  79.243  131.807 1.00 118.95 ? 183 THR R O   1 
ATOM 7150 C CB  . THR E 5 236 ? 95.411  76.205  131.937 1.00 124.76 ? 183 THR R CB  1 
ATOM 7151 O OG1 . THR E 5 236 ? 94.003  76.423  131.784 1.00 124.43 ? 183 THR R OG1 1 
ATOM 7152 C CG2 . THR E 5 236 ? 95.647  74.801  132.471 1.00 123.85 ? 183 THR R CG2 1 
ATOM 7153 N N   . MET E 5 237 ? 94.602  79.198  132.413 1.00 122.92 ? 184 MET R N   1 
ATOM 7154 C CA  . MET E 5 237 ? 94.374  80.551  131.920 1.00 122.34 ? 184 MET R CA  1 
ATOM 7155 C C   . MET E 5 237 ? 95.037  81.596  132.809 1.00 122.34 ? 184 MET R C   1 
ATOM 7156 O O   . MET E 5 237 ? 95.430  82.661  132.320 1.00 122.58 ? 184 MET R O   1 
ATOM 7157 C CB  . MET E 5 237 ? 92.874  80.824  131.813 1.00 122.66 ? 184 MET R CB  1 
ATOM 7158 C CG  . MET E 5 237 ? 92.143  79.909  130.845 1.00 123.04 ? 184 MET R CG  1 
ATOM 7159 S SD  . MET E 5 237 ? 92.780  80.029  129.163 1.00 125.71 ? 184 MET R SD  1 
ATOM 7160 C CE  . MET E 5 237 ? 92.513  81.768  128.826 1.00 120.36 ? 184 MET R CE  1 
ATOM 7161 N N   . CYS E 5 238 ? 95.163  81.317  134.109 1.00 125.98 ? 185 CYS R N   1 
ATOM 7162 C CA  . CYS E 5 238 ? 95.812  82.261  135.015 1.00 125.28 ? 185 CYS R CA  1 
ATOM 7163 C C   . CYS E 5 238 ? 97.252  82.541  134.602 1.00 123.83 ? 185 CYS R C   1 
ATOM 7164 O O   . CYS E 5 238 ? 97.689  83.698  134.597 1.00 125.21 ? 185 CYS R O   1 
ATOM 7165 C CB  . CYS E 5 238 ? 95.757  81.730  136.446 1.00 126.64 ? 185 CYS R CB  1 
ATOM 7166 S SG  . CYS E 5 238 ? 96.969  82.454  137.579 1.00 129.12 ? 185 CYS R SG  1 
ATOM 7167 N N   . THR E 5 239 ? 98.006  81.497  134.255 1.00 119.29 ? 186 THR R N   1 
ATOM 7168 C CA  . THR E 5 239 ? 99.359  81.707  133.750 1.00 120.03 ? 186 THR R CA  1 
ATOM 7169 C C   . THR E 5 239 ? 99.347  82.434  132.410 1.00 120.15 ? 186 THR R C   1 
ATOM 7170 O O   . THR E 5 239 ? 100.166 83.330  132.176 1.00 119.44 ? 186 THR R O   1 
ATOM 7171 C CB  . THR E 5 239 ? 100.088 80.368  133.626 1.00 120.92 ? 186 THR R CB  1 
ATOM 7172 O OG1 . THR E 5 239 ? 100.109 79.713  134.900 1.00 123.53 ? 186 THR R OG1 1 
ATOM 7173 C CG2 . THR E 5 239 ? 101.519 80.579  133.151 1.00 119.33 ? 186 THR R CG2 1 
ATOM 7174 N N   . LEU E 5 240 ? 98.422  82.065  131.520 1.00 109.96 ? 187 LEU R N   1 
ATOM 7175 C CA  . LEU E 5 240 ? 98.406  82.650  130.182 1.00 108.24 ? 187 LEU R CA  1 
ATOM 7176 C C   . LEU E 5 240 ? 97.963  84.109  130.202 1.00 107.73 ? 187 LEU R C   1 
ATOM 7177 O O   . LEU E 5 240 ? 98.573  84.954  129.538 1.00 109.00 ? 187 LEU R O   1 
ATOM 7178 C CB  . LEU E 5 240 ? 97.502  81.829  129.264 1.00 108.71 ? 187 LEU R CB  1 
ATOM 7179 C CG  . LEU E 5 240 ? 97.403  82.323  127.819 1.00 106.60 ? 187 LEU R CG  1 
ATOM 7180 C CD1 . LEU E 5 240 ? 98.774  82.335  127.161 1.00 105.72 ? 187 LEU R CD1 1 
ATOM 7181 C CD2 . LEU E 5 240 ? 96.430  81.468  127.022 1.00 107.98 ? 187 LEU R CD2 1 
ATOM 7182 N N   . ILE E 5 241 ? 96.905  84.425  130.952 1.00 103.11 ? 188 ILE R N   1 
ATOM 7183 C CA  . ILE E 5 241 ? 96.389  85.792  130.956 1.00 100.72 ? 188 ILE R CA  1 
ATOM 7184 C C   . ILE E 5 241 ? 97.353  86.736  131.665 1.00 100.98 ? 188 ILE R C   1 
ATOM 7185 O O   . ILE E 5 241 ? 97.560  87.874  131.224 1.00 104.21 ? 188 ILE R O   1 
ATOM 7186 C CB  . ILE E 5 241 ? 94.983  85.832  131.583 1.00 100.62 ? 188 ILE R CB  1 
ATOM 7187 C CG1 . ILE E 5 241 ? 93.995  85.052  130.712 1.00 105.47 ? 188 ILE R CG1 1 
ATOM 7188 C CG2 . ILE E 5 241 ? 94.516  87.267  131.767 1.00 98.96  ? 188 ILE R CG2 1 
ATOM 7189 C CD1 . ILE E 5 241 ? 92.586  85.014  131.261 1.00 106.65 ? 188 ILE R CD1 1 
ATOM 7190 N N   . THR E 5 242 ? 97.960  86.288  132.766 1.00 96.46  ? 189 THR R N   1 
ATOM 7191 C CA  . THR E 5 242 ? 98.922  87.137  133.464 1.00 96.61  ? 189 THR R CA  1 
ATOM 7192 C C   . THR E 5 242 ? 100.141 87.420  132.594 1.00 95.24  ? 189 THR R C   1 
ATOM 7193 O O   . THR E 5 242 ? 100.640 88.551  132.559 1.00 99.38  ? 189 THR R O   1 
ATOM 7194 C CB  . THR E 5 242 ? 99.344  86.488  134.782 1.00 98.00  ? 189 THR R CB  1 
ATOM 7195 O OG1 . THR E 5 242 ? 98.185  86.230  135.585 1.00 102.01 ? 189 THR R OG1 1 
ATOM 7196 C CG2 . THR E 5 242 ? 100.289 87.402  135.550 1.00 96.77  ? 189 THR R CG2 1 
ATOM 7197 N N   . ALA E 5 243 ? 100.631 86.404  131.879 1.00 90.90  ? 190 ALA R N   1 
ATOM 7198 C CA  . ALA E 5 243 ? 101.768 86.608  130.987 1.00 93.88  ? 190 ALA R CA  1 
ATOM 7199 C C   . ALA E 5 243 ? 101.389 87.463  129.784 1.00 94.69  ? 190 ALA R C   1 
ATOM 7200 O O   . ALA E 5 243 ? 102.178 88.308  129.344 1.00 94.87  ? 190 ALA R O   1 
ATOM 7201 C CB  . ALA E 5 243 ? 102.325 85.262  130.529 1.00 96.85  ? 190 ALA R CB  1 
ATOM 7202 N N   . MET E 5 244 ? 100.193 87.248  129.231 1.00 89.94  ? 191 MET R N   1 
ATOM 7203 C CA  . MET E 5 244 ? 99.748  88.055  128.099 1.00 85.86  ? 191 MET R CA  1 
ATOM 7204 C C   . MET E 5 244 ? 99.578  89.516  128.496 1.00 86.61  ? 191 MET R C   1 
ATOM 7205 O O   . MET E 5 244 ? 99.947  90.420  127.737 1.00 88.96  ? 191 MET R O   1 
ATOM 7206 C CB  . MET E 5 244 ? 98.442  87.493  127.538 1.00 84.40  ? 191 MET R CB  1 
ATOM 7207 C CG  . MET E 5 244 ? 97.949  88.188  126.281 1.00 84.40  ? 191 MET R CG  1 
ATOM 7208 S SD  . MET E 5 244 ? 99.091  87.999  124.899 1.00 93.16  ? 191 MET R SD  1 
ATOM 7209 C CE  . MET E 5 244 ? 98.199  88.854  123.603 1.00 92.08  ? 191 MET R CE  1 
ATOM 7210 N N   . ASP E 5 245 ? 99.019  89.766  129.682 1.00 84.92  ? 192 ASP R N   1 
ATOM 7211 C CA  . ASP E 5 245 ? 98.838  91.138  130.143 1.00 83.01  ? 192 ASP R CA  1 
ATOM 7212 C C   . ASP E 5 245 ? 100.180 91.803  130.420 1.00 84.39  ? 192 ASP R C   1 
ATOM 7213 O O   . ASP E 5 245 ? 100.407 92.955  130.033 1.00 89.74  ? 192 ASP R O   1 
ATOM 7214 C CB  . ASP E 5 245 ? 97.953  91.163  131.390 1.00 87.06  ? 192 ASP R CB  1 
ATOM 7215 C CG  . ASP E 5 245 ? 97.568  92.571  131.803 1.00 90.38  ? 192 ASP R CG  1 
ATOM 7216 O OD1 . ASP E 5 245 ? 96.685  93.163  131.148 1.00 94.06  ? 192 ASP R OD1 1 
ATOM 7217 O OD2 . ASP E 5 245 ? 98.148  93.085  132.782 1.00 90.73  ? 192 ASP R OD2 1 
ATOM 7218 N N   . ALA E 5 246 ? 101.081 91.089  131.099 1.00 78.03  ? 193 ALA R N   1 
ATOM 7219 C CA  . ALA E 5 246 ? 102.391 91.647  131.414 1.00 74.73  ? 193 ALA R CA  1 
ATOM 7220 C C   . ALA E 5 246 ? 103.220 91.895  130.161 1.00 76.08  ? 193 ALA R C   1 
ATOM 7221 O O   . ALA E 5 246 ? 104.018 92.839  130.127 1.00 82.56  ? 193 ALA R O   1 
ATOM 7222 C CB  . ALA E 5 246 ? 103.142 90.721  132.370 1.00 76.48  ? 193 ALA R CB  1 
ATOM 7223 N N   . ASN E 5 247 ? 103.056 91.063  129.130 1.00 72.21  ? 194 ASN R N   1 
ATOM 7224 C CA  . ASN E 5 247 ? 103.803 91.269  127.893 1.00 70.47  ? 194 ASN R CA  1 
ATOM 7225 C C   . ASN E 5 247 ? 103.393 92.565  127.207 1.00 67.08  ? 194 ASN R C   1 
ATOM 7226 O O   . ASN E 5 247 ? 104.243 93.283  126.667 1.00 69.25  ? 194 ASN R O   1 
ATOM 7227 C CB  . ASN E 5 247 ? 103.603 90.083  126.951 1.00 73.48  ? 194 ASN R CB  1 
ATOM 7228 C CG  . ASN E 5 247 ? 104.355 90.245  125.646 1.00 69.05  ? 194 ASN R CG  1 
ATOM 7229 O OD1 . ASN E 5 247 ? 103.775 90.608  124.623 1.00 68.88  ? 194 ASN R OD1 1 
ATOM 7230 N ND2 . ASN E 5 247 ? 105.656 89.984  125.678 1.00 67.18  ? 194 ASN R ND2 1 
ATOM 7231 N N   . SER E 5 248 ? 102.096 92.879  127.216 1.00 65.76  ? 195 SER R N   1 
ATOM 7232 C CA  . SER E 5 248 ? 101.623 94.089  126.555 1.00 67.70  ? 195 SER R CA  1 
ATOM 7233 C C   . SER E 5 248 ? 102.134 95.346  127.247 1.00 66.22  ? 195 SER R C   1 
ATOM 7234 O O   . SER E 5 248 ? 102.384 96.358  126.583 1.00 67.24  ? 195 SER R O   1 
ATOM 7235 C CB  . SER E 5 248 ? 100.096 94.094  126.500 1.00 67.16  ? 195 SER R CB  1 
ATOM 7236 O OG  . SER E 5 248 ? 99.608  92.986  125.765 1.00 64.69  ? 195 SER R OG  1 
ATOM 7237 N N   . GLN E 5 249 ? 102.295 95.305  128.571 1.00 67.92  ? 196 GLN R N   1 
ATOM 7238 C CA  . GLN E 5 249 ? 102.856 96.449  129.280 1.00 61.75  ? 196 GLN R CA  1 
ATOM 7239 C C   . GLN E 5 249 ? 104.319 96.660  128.911 1.00 65.04  ? 196 GLN R C   1 
ATOM 7240 O O   . GLN E 5 249 ? 104.744 97.790  128.640 1.00 74.41  ? 196 GLN R O   1 
ATOM 7241 C CB  . GLN E 5 249 ? 102.700 96.253  130.789 1.00 63.79  ? 196 GLN R CB  1 
ATOM 7242 C CG  . GLN E 5 249 ? 103.484 97.239  131.638 1.00 65.97  ? 196 GLN R CG  1 
ATOM 7243 C CD  . GLN E 5 249 ? 103.427 96.905  133.116 1.00 70.38  ? 196 GLN R CD  1 
ATOM 7244 O OE1 . GLN E 5 249 ? 102.595 96.109  133.552 1.00 72.06  ? 196 GLN R OE1 1 
ATOM 7245 N NE2 . GLN E 5 249 ? 104.311 97.516  133.896 1.00 76.24  ? 196 GLN R NE2 1 
ATOM 7246 N N   . PHE E 5 250 ? 105.109 95.585  128.898 1.00 55.21  ? 197 PHE R N   1 
ATOM 7247 C CA  . PHE E 5 250 ? 106.523 95.721  128.567 1.00 54.77  ? 197 PHE R CA  1 
ATOM 7248 C C   . PHE E 5 250 ? 106.724 96.065  127.095 1.00 63.90  ? 197 PHE R C   1 
ATOM 7249 O O   . PHE E 5 250 ? 107.585 96.884  126.756 1.00 69.51  ? 197 PHE R O   1 
ATOM 7250 C CB  . PHE E 5 250 ? 107.273 94.436  128.922 1.00 56.18  ? 197 PHE R CB  1 
ATOM 7251 C CG  . PHE E 5 250 ? 107.646 94.329  130.374 1.00 60.71  ? 197 PHE R CG  1 
ATOM 7252 C CD1 . PHE E 5 250 ? 106.704 93.967  131.323 1.00 68.37  ? 197 PHE R CD1 1 
ATOM 7253 C CD2 . PHE E 5 250 ? 108.941 94.588  130.789 1.00 63.55  ? 197 PHE R CD2 1 
ATOM 7254 C CE1 . PHE E 5 250 ? 107.048 93.866  132.658 1.00 66.81  ? 197 PHE R CE1 1 
ATOM 7255 C CE2 . PHE E 5 250 ? 109.291 94.489  132.121 1.00 72.41  ? 197 PHE R CE2 1 
ATOM 7256 C CZ  . PHE E 5 250 ? 108.343 94.128  133.057 1.00 70.15  ? 197 PHE R CZ  1 
ATOM 7257 N N   . THR E 5 251 ? 105.937 95.451  126.206 1.00 64.52  ? 198 THR R N   1 
ATOM 7258 C CA  . THR E 5 251 ? 106.095 95.699  124.775 1.00 58.22  ? 198 THR R CA  1 
ATOM 7259 C C   . THR E 5 251 ? 105.694 97.122  124.397 1.00 61.19  ? 198 THR R C   1 
ATOM 7260 O O   . THR E 5 251 ? 106.386 97.775  123.607 1.00 63.92  ? 198 THR R O   1 
ATOM 7261 C CB  . THR E 5 251 ? 105.286 94.685  123.967 1.00 64.60  ? 198 THR R CB  1 
ATOM 7262 O OG1 . THR E 5 251 ? 105.576 93.362  124.434 1.00 81.99  ? 198 THR R OG1 1 
ATOM 7263 C CG2 . THR E 5 251 ? 105.648 94.777  122.494 1.00 58.66  ? 198 THR R CG2 1 
ATOM 7264 N N   . SER E 5 252 ? 104.576 97.615  124.940 1.00 69.71  ? 199 SER R N   1 
ATOM 7265 C CA  . SER E 5 252 ? 104.132 98.967  124.612 1.00 63.33  ? 199 SER R CA  1 
ATOM 7266 C C   . SER E 5 252 ? 105.142 100.006 125.079 1.00 58.00  ? 199 SER R C   1 
ATOM 7267 O O   . SER E 5 252 ? 105.384 101.003 124.389 1.00 66.29  ? 199 SER R O   1 
ATOM 7268 C CB  . SER E 5 252 ? 102.761 99.238  125.231 1.00 61.85  ? 199 SER R CB  1 
ATOM 7269 O OG  . SER E 5 252 ? 102.808 99.139  126.643 1.00 65.17  ? 199 SER R OG  1 
ATOM 7270 N N   . THR E 5 253 ? 105.733 99.794  126.255 1.00 50.76  ? 200 THR R N   1 
ATOM 7271 C CA  . THR E 5 253 ? 106.748 100.715 126.750 1.00 50.44  ? 200 THR R CA  1 
ATOM 7272 C C   . THR E 5 253 ? 108.004 100.683 125.886 1.00 58.05  ? 200 THR R C   1 
ATOM 7273 O O   . THR E 5 253 ? 108.657 101.717 125.707 1.00 70.31  ? 200 THR R O   1 
ATOM 7274 C CB  . THR E 5 253 ? 107.092 100.385 128.203 1.00 57.23  ? 200 THR R CB  1 
ATOM 7275 O OG1 . THR E 5 253 ? 105.886 100.282 128.970 1.00 58.62  ? 200 THR R OG1 1 
ATOM 7276 C CG2 . THR E 5 253 ? 107.969 101.466 128.802 1.00 62.21  ? 200 THR R CG2 1 
ATOM 7277 N N   . TYR E 5 254 ? 108.357 99.516  125.341 1.00 53.74  ? 201 TYR R N   1 
ATOM 7278 C CA  . TYR E 5 254 ? 109.544 99.430  124.495 1.00 59.99  ? 201 TYR R CA  1 
ATOM 7279 C C   . TYR E 5 254 ? 109.312 100.063 123.127 1.00 62.92  ? 201 TYR R C   1 
ATOM 7280 O O   . TYR E 5 254 ? 110.216 100.699 122.574 1.00 60.36  ? 201 TYR R O   1 
ATOM 7281 C CB  . TYR E 5 254 ? 109.973 97.972  124.334 1.00 59.78  ? 201 TYR R CB  1 
ATOM 7282 C CG  . TYR E 5 254 ? 110.404 97.309  125.621 1.00 60.76  ? 201 TYR R CG  1 
ATOM 7283 C CD1 . TYR E 5 254 ? 110.825 98.063  126.707 1.00 61.90  ? 201 TYR R CD1 1 
ATOM 7284 C CD2 . TYR E 5 254 ? 110.393 95.927  125.747 1.00 66.08  ? 201 TYR R CD2 1 
ATOM 7285 C CE1 . TYR E 5 254 ? 111.219 97.458  127.884 1.00 69.62  ? 201 TYR R CE1 1 
ATOM 7286 C CE2 . TYR E 5 254 ? 110.785 95.314  126.919 1.00 69.27  ? 201 TYR R CE2 1 
ATOM 7287 C CZ  . TYR E 5 254 ? 111.198 96.083  127.984 1.00 74.54  ? 201 TYR R CZ  1 
ATOM 7288 O OH  . TYR E 5 254 ? 111.590 95.475  129.155 1.00 75.67  ? 201 TYR R OH  1 
ATOM 7289 N N   . ILE E 5 255 ? 108.113 99.899  122.563 1.00 56.60  ? 202 ILE R N   1 
ATOM 7290 C CA  . ILE E 5 255 ? 107.813 100.531 121.282 1.00 50.48  ? 202 ILE R CA  1 
ATOM 7291 C C   . ILE E 5 255 ? 107.742 102.044 121.436 1.00 55.53  ? 202 ILE R C   1 
ATOM 7292 O O   . ILE E 5 255 ? 108.169 102.793 120.549 1.00 59.34  ? 202 ILE R O   1 
ATOM 7293 C CB  . ILE E 5 255 ? 106.514 99.957  120.688 1.00 35.18  ? 202 ILE R CB  1 
ATOM 7294 C CG1 . ILE E 5 255 ? 106.679 98.466  120.396 1.00 45.58  ? 202 ILE R CG1 1 
ATOM 7295 C CG2 . ILE E 5 255 ? 106.142 100.690 119.412 1.00 44.62  ? 202 ILE R CG2 1 
ATOM 7296 C CD1 . ILE E 5 255 ? 105.478 97.834  119.729 1.00 51.42  ? 202 ILE R CD1 1 
ATOM 7297 N N   . LEU E 5 256 ? 107.211 102.519 122.564 1.00 54.06  ? 203 LEU R N   1 
ATOM 7298 C CA  . LEU E 5 256 ? 107.191 103.956 122.817 1.00 51.88  ? 203 LEU R CA  1 
ATOM 7299 C C   . LEU E 5 256 ? 108.604 104.501 122.972 1.00 46.70  ? 203 LEU R C   1 
ATOM 7300 O O   . LEU E 5 256 ? 108.901 105.612 122.517 1.00 55.09  ? 203 LEU R O   1 
ATOM 7301 C CB  . LEU E 5 256 ? 106.349 104.263 124.054 1.00 50.02  ? 203 LEU R CB  1 
ATOM 7302 C CG  . LEU E 5 256 ? 106.206 105.745 124.406 1.00 54.73  ? 203 LEU R CG  1 
ATOM 7303 C CD1 . LEU E 5 256 ? 105.623 106.510 123.229 1.00 56.95  ? 203 LEU R CD1 1 
ATOM 7304 C CD2 . LEU E 5 256 ? 105.347 105.929 125.646 1.00 54.21  ? 203 LEU R CD2 1 
ATOM 7305 N N   . THR E 5 257 ? 109.488 103.737 123.618 1.00 34.44  ? 204 THR R N   1 
ATOM 7306 C CA  . THR E 5 257 ? 110.882 104.151 123.730 1.00 35.38  ? 204 THR R CA  1 
ATOM 7307 C C   . THR E 5 257 ? 111.565 104.160 122.368 1.00 51.09  ? 204 THR R C   1 
ATOM 7308 O O   . THR E 5 257 ? 112.324 105.084 122.054 1.00 63.31  ? 204 THR R O   1 
ATOM 7309 C CB  . THR E 5 257 ? 111.627 103.224 124.691 1.00 43.65  ? 204 THR R CB  1 
ATOM 7310 O OG1 . THR E 5 257 ? 110.970 103.226 125.963 1.00 67.03  ? 204 THR R OG1 1 
ATOM 7311 C CG2 . THR E 5 257 ? 113.066 103.682 124.871 1.00 45.81  ? 204 THR R CG2 1 
ATOM 7312 N N   . ALA E 5 258 ? 111.307 103.142 121.543 1.00 52.56  ? 205 ALA R N   1 
ATOM 7313 C CA  . ALA E 5 258 ? 111.940 103.083 120.230 1.00 50.90  ? 205 ALA R CA  1 
ATOM 7314 C C   . ALA E 5 258 ? 111.334 104.095 119.267 1.00 48.00  ? 205 ALA R C   1 
ATOM 7315 O O   . ALA E 5 258 ? 112.016 104.557 118.346 1.00 50.49  ? 205 ALA R O   1 
ATOM 7316 C CB  . ALA E 5 258 ? 111.831 101.672 119.655 1.00 48.55  ? 205 ALA R CB  1 
ATOM 7317 N N   . MET E 5 259 ? 110.061 104.450 119.459 1.00 41.47  ? 206 MET R N   1 
ATOM 7318 C CA  . MET E 5 259 ? 109.452 105.488 118.638 1.00 43.07  ? 206 MET R CA  1 
ATOM 7319 C C   . MET E 5 259 ? 109.991 106.870 118.975 1.00 55.00  ? 206 MET R C   1 
ATOM 7320 O O   . MET E 5 259 ? 109.828 107.799 118.177 1.00 53.83  ? 206 MET R O   1 
ATOM 7321 C CB  . MET E 5 259 ? 107.932 105.470 118.805 1.00 35.75  ? 206 MET R CB  1 
ATOM 7322 C CG  . MET E 5 259 ? 107.169 106.144 117.677 1.00 45.78  ? 206 MET R CG  1 
ATOM 7323 S SD  . MET E 5 259 ? 105.383 106.008 117.874 1.00 62.48  ? 206 MET R SD  1 
ATOM 7324 C CE  . MET E 5 259 ? 105.141 106.943 119.382 1.00 52.73  ? 206 MET R CE  1 
ATOM 7325 N N   . ALA E 5 260 ? 110.637 107.025 120.131 1.00 58.48  ? 207 ALA R N   1 
ATOM 7326 C CA  . ALA E 5 260 ? 111.266 108.289 120.487 1.00 50.72  ? 207 ALA R CA  1 
ATOM 7327 C C   . ALA E 5 260 ? 112.726 108.349 120.068 1.00 51.53  ? 207 ALA R C   1 
ATOM 7328 O O   . ALA E 5 260 ? 113.229 109.434 119.755 1.00 71.44  ? 207 ALA R O   1 
ATOM 7329 C CB  . ALA E 5 260 ? 111.154 108.529 121.995 1.00 55.27  ? 207 ALA R CB  1 
ATOM 7330 N N   . ILE E 5 261 ? 113.418 107.208 120.057 1.00 35.22  ? 208 ILE R N   1 
ATOM 7331 C CA  . ILE E 5 261 ? 114.760 107.163 119.487 1.00 41.79  ? 208 ILE R CA  1 
ATOM 7332 C C   . ILE E 5 261 ? 114.699 107.365 117.978 1.00 46.61  ? 208 ILE R C   1 
ATOM 7333 O O   . ILE E 5 261 ? 115.588 107.987 117.384 1.00 54.41  ? 208 ILE R O   1 
ATOM 7334 C CB  . ILE E 5 261 ? 115.454 105.842 119.864 1.00 43.07  ? 208 ILE R CB  1 
ATOM 7335 C CG1 . ILE E 5 261 ? 115.527 105.701 121.385 1.00 46.48  ? 208 ILE R CG1 1 
ATOM 7336 C CG2 . ILE E 5 261 ? 116.852 105.781 119.270 1.00 42.66  ? 208 ILE R CG2 1 
ATOM 7337 C CD1 . ILE E 5 261 ? 116.222 104.439 121.854 1.00 50.68  ? 208 ILE R CD1 1 
ATOM 7338 N N   . ASP E 5 262 ? 113.651 106.844 117.334 1.00 51.86  ? 209 ASP R N   1 
ATOM 7339 C CA  . ASP E 5 262 ? 113.464 107.081 115.906 1.00 59.68  ? 209 ASP R CA  1 
ATOM 7340 C C   . ASP E 5 262 ? 113.293 108.565 115.603 1.00 63.25  ? 209 ASP R C   1 
ATOM 7341 O O   . ASP E 5 262 ? 113.861 109.077 114.631 1.00 66.59  ? 209 ASP R O   1 
ATOM 7342 C CB  . ASP E 5 262 ? 112.257 106.294 115.399 1.00 63.80  ? 209 ASP R CB  1 
ATOM 7343 C CG  . ASP E 5 262 ? 112.019 106.483 113.915 1.00 69.67  ? 209 ASP R CG  1 
ATOM 7344 O OD1 . ASP E 5 262 ? 112.878 106.061 113.113 1.00 70.24  ? 209 ASP R OD1 1 
ATOM 7345 O OD2 . ASP E 5 262 ? 110.975 107.063 113.551 1.00 70.40  ? 209 ASP R OD2 1 
ATOM 7346 N N   . ARG E 5 263 ? 112.510 109.271 116.422 1.00 50.12  ? 210 ARG R N   1 
ATOM 7347 C CA  . ARG E 5 263 ? 112.328 110.704 116.219 1.00 45.57  ? 210 ARG R CA  1 
ATOM 7348 C C   . ARG E 5 263 ? 113.602 111.480 116.526 1.00 40.99  ? 210 ARG R C   1 
ATOM 7349 O O   . ARG E 5 263 ? 113.863 112.512 115.898 1.00 55.70  ? 210 ARG R O   1 
ATOM 7350 C CB  . ARG E 5 263 ? 111.167 111.206 117.077 1.00 50.16  ? 210 ARG R CB  1 
ATOM 7351 C CG  . ARG E 5 263 ? 109.831 110.608 116.675 1.00 54.53  ? 210 ARG R CG  1 
ATOM 7352 C CD  . ARG E 5 263 ? 108.711 111.032 117.607 1.00 59.87  ? 210 ARG R CD  1 
ATOM 7353 N NE  . ARG E 5 263 ? 107.446 110.403 117.242 1.00 58.06  ? 210 ARG R NE  1 
ATOM 7354 C CZ  . ARG E 5 263 ? 106.311 110.566 117.907 1.00 54.18  ? 210 ARG R CZ  1 
ATOM 7355 N NH1 . ARG E 5 263 ? 106.242 111.336 118.980 1.00 46.66  ? 210 ARG R NH1 1 
ATOM 7356 N NH2 . ARG E 5 263 ? 105.217 109.938 117.486 1.00 55.83  ? 210 ARG R NH2 1 
ATOM 7357 N N   . TYR E 5 264 ? 114.396 111.007 117.489 1.00 43.55  ? 211 TYR R N   1 
ATOM 7358 C CA  . TYR E 5 264 ? 115.687 111.630 117.760 1.00 43.21  ? 211 TYR R CA  1 
ATOM 7359 C C   . TYR E 5 264 ? 116.616 111.509 116.559 1.00 58.03  ? 211 TYR R C   1 
ATOM 7360 O O   . TYR E 5 264 ? 117.297 112.473 116.190 1.00 70.97  ? 211 TYR R O   1 
ATOM 7361 C CB  . TYR E 5 264 ? 116.319 110.997 118.999 1.00 48.98  ? 211 TYR R CB  1 
ATOM 7362 C CG  . TYR E 5 264 ? 117.763 111.384 119.235 1.00 48.51  ? 211 TYR R CG  1 
ATOM 7363 C CD1 . TYR E 5 264 ? 118.090 112.561 119.891 1.00 59.82  ? 211 TYR R CD1 1 
ATOM 7364 C CD2 . TYR E 5 264 ? 118.799 110.563 118.810 1.00 52.28  ? 211 TYR R CD2 1 
ATOM 7365 C CE1 . TYR E 5 264 ? 119.410 112.914 120.111 1.00 64.00  ? 211 TYR R CE1 1 
ATOM 7366 C CE2 . TYR E 5 264 ? 120.118 110.907 119.023 1.00 60.05  ? 211 TYR R CE2 1 
ATOM 7367 C CZ  . TYR E 5 264 ? 120.419 112.083 119.673 1.00 63.71  ? 211 TYR R CZ  1 
ATOM 7368 O OH  . TYR E 5 264 ? 121.733 112.429 119.888 1.00 61.57  ? 211 TYR R OH  1 
ATOM 7369 N N   . LEU E 5 265 ? 116.658 110.329 115.936 1.00 59.47  ? 212 LEU R N   1 
ATOM 7370 C CA  . LEU E 5 265 ? 117.545 110.124 114.796 1.00 57.96  ? 212 LEU R CA  1 
ATOM 7371 C C   . LEU E 5 265 ? 117.067 110.896 113.573 1.00 58.77  ? 212 LEU R C   1 
ATOM 7372 O O   . LEU E 5 265 ? 117.882 111.396 112.790 1.00 58.30  ? 212 LEU R O   1 
ATOM 7373 C CB  . LEU E 5 265 ? 117.656 108.632 114.481 1.00 59.96  ? 212 LEU R CB  1 
ATOM 7374 C CG  . LEU E 5 265 ? 118.361 107.771 115.532 1.00 62.38  ? 212 LEU R CG  1 
ATOM 7375 C CD1 . LEU E 5 265 ? 118.399 106.314 115.098 1.00 61.38  ? 212 LEU R CD1 1 
ATOM 7376 C CD2 . LEU E 5 265 ? 119.764 108.287 115.799 1.00 59.41  ? 212 LEU R CD2 1 
ATOM 7377 N N   . ALA E 5 266 ? 115.749 111.000 113.388 1.00 64.18  ? 213 ALA R N   1 
ATOM 7378 C CA  . ALA E 5 266 ? 115.199 111.731 112.254 1.00 66.47  ? 213 ALA R CA  1 
ATOM 7379 C C   . ALA E 5 266 ? 115.444 113.232 112.331 1.00 68.81  ? 213 ALA R C   1 
ATOM 7380 O O   . ALA E 5 266 ? 115.266 113.919 111.319 1.00 73.78  ? 213 ALA R O   1 
ATOM 7381 C CB  . ALA E 5 266 ? 113.698 111.462 112.139 1.00 59.63  ? 213 ALA R CB  1 
ATOM 7382 N N   . THR E 5 267 ? 115.845 113.757 113.488 1.00 58.04  ? 214 THR R N   1 
ATOM 7383 C CA  . THR E 5 267 ? 116.021 115.191 113.681 1.00 51.22  ? 214 THR R CA  1 
ATOM 7384 C C   . THR E 5 267 ? 117.473 115.592 113.892 1.00 54.15  ? 214 THR R C   1 
ATOM 7385 O O   . THR E 5 267 ? 117.984 116.459 113.176 1.00 72.37  ? 214 THR R O   1 
ATOM 7386 C CB  . THR E 5 267 ? 115.175 115.668 114.871 1.00 55.07  ? 214 THR R CB  1 
ATOM 7387 O OG1 . THR E 5 267 ? 113.786 115.478 114.577 1.00 56.04  ? 214 THR R OG1 1 
ATOM 7388 C CG2 . THR E 5 267 ? 115.433 117.139 115.153 1.00 59.23  ? 214 THR R CG2 1 
ATOM 7389 N N   . VAL E 5 268 ? 118.159 114.982 114.861 1.00 48.74  ? 215 VAL R N   1 
ATOM 7390 C CA  . VAL E 5 268 ? 119.527 115.390 115.164 1.00 61.95  ? 215 VAL R CA  1 
ATOM 7391 C C   . VAL E 5 268 ? 120.492 114.902 114.090 1.00 66.87  ? 215 VAL R C   1 
ATOM 7392 O O   . VAL E 5 268 ? 121.517 115.543 113.828 1.00 72.67  ? 215 VAL R O   1 
ATOM 7393 C CB  . VAL E 5 268 ? 119.929 114.888 116.563 1.00 63.85  ? 215 VAL R CB  1 
ATOM 7394 C CG1 . VAL E 5 268 ? 121.309 115.405 116.951 1.00 68.36  ? 215 VAL R CG1 1 
ATOM 7395 C CG2 . VAL E 5 268 ? 118.891 115.308 117.590 1.00 65.04  ? 215 VAL R CG2 1 
ATOM 7396 N N   . HIS E 5 269 ? 120.182 113.785 113.438 1.00 63.27  ? 216 HIS R N   1 
ATOM 7397 C CA  . HIS E 5 269 ? 121.017 113.226 112.376 1.00 70.63  ? 216 HIS R CA  1 
ATOM 7398 C C   . HIS E 5 269 ? 120.156 112.964 111.148 1.00 73.64  ? 216 HIS R C   1 
ATOM 7399 O O   . HIS E 5 269 ? 119.878 111.811 110.801 1.00 80.78  ? 216 HIS R O   1 
ATOM 7400 C CB  . HIS E 5 269 ? 121.712 111.946 112.843 1.00 75.02  ? 216 HIS R CB  1 
ATOM 7401 C CG  . HIS E 5 269 ? 122.685 112.160 113.960 1.00 72.19  ? 216 HIS R CG  1 
ATOM 7402 N ND1 . HIS E 5 269 ? 124.050 112.164 113.769 1.00 68.75  ? 216 HIS R ND1 1 
ATOM 7403 C CD2 . HIS E 5 269 ? 122.490 112.374 115.283 1.00 73.11  ? 216 HIS R CD2 1 
ATOM 7404 C CE1 . HIS E 5 269 ? 124.654 112.374 114.926 1.00 72.76  ? 216 HIS R CE1 1 
ATOM 7405 N NE2 . HIS E 5 269 ? 123.730 112.504 115.860 1.00 75.08  ? 216 HIS R NE2 1 
ATOM 7406 N N   . PRO E 5 270 ? 119.715 114.022 110.459 1.00 69.34  ? 217 PRO R N   1 
ATOM 7407 C CA  . PRO E 5 270 ? 118.774 113.824 109.348 1.00 68.69  ? 217 PRO R CA  1 
ATOM 7408 C C   . PRO E 5 270 ? 119.418 113.268 108.091 1.00 73.17  ? 217 PRO R C   1 
ATOM 7409 O O   . PRO E 5 270 ? 118.704 112.698 107.254 1.00 80.01  ? 217 PRO R O   1 
ATOM 7410 C CB  . PRO E 5 270 ? 118.213 115.236 109.098 1.00 65.81  ? 217 PRO R CB  1 
ATOM 7411 C CG  . PRO E 5 270 ? 118.954 116.160 110.055 1.00 70.82  ? 217 PRO R CG  1 
ATOM 7412 C CD  . PRO E 5 270 ? 120.143 115.424 110.565 1.00 70.57  ? 217 PRO R CD  1 
ATOM 7413 N N   . ILE E 5 271 ? 120.728 113.412 107.930 1.00 72.69  ? 218 ILE R N   1 
ATOM 7414 C CA  . ILE E 5 271 ? 121.435 112.932 106.747 1.00 71.17  ? 218 ILE R CA  1 
ATOM 7415 C C   . ILE E 5 271 ? 122.092 111.580 106.994 1.00 74.54  ? 218 ILE R C   1 
ATOM 7416 O O   . ILE E 5 271 ? 121.973 110.666 106.178 1.00 77.21  ? 218 ILE R O   1 
ATOM 7417 C CB  . ILE E 5 271 ? 122.470 113.980 106.281 1.00 69.87  ? 218 ILE R CB  1 
ATOM 7418 C CG1 . ILE E 5 271 ? 121.774 115.301 105.952 1.00 71.86  ? 218 ILE R CG1 1 
ATOM 7419 C CG2 . ILE E 5 271 ? 123.246 113.466 105.080 1.00 71.30  ? 218 ILE R CG2 1 
ATOM 7420 C CD1 . ILE E 5 271 ? 120.688 115.169 104.911 1.00 72.78  ? 218 ILE R CD1 1 
ATOM 7421 N N   . SER E 5 272 ? 122.791 111.435 108.122 1.00 75.34  ? 219 SER R N   1 
ATOM 7422 C CA  . SER E 5 272 ? 123.536 110.208 108.380 1.00 75.17  ? 219 SER R CA  1 
ATOM 7423 C C   . SER E 5 272 ? 122.635 109.039 108.756 1.00 77.84  ? 219 SER R C   1 
ATOM 7424 O O   . SER E 5 272 ? 123.079 107.888 108.687 1.00 79.82  ? 219 SER R O   1 
ATOM 7425 C CB  . SER E 5 272 ? 124.568 110.440 109.484 1.00 77.04  ? 219 SER R CB  1 
ATOM 7426 O OG  . SER E 5 272 ? 123.946 110.843 110.691 1.00 75.70  ? 219 SER R OG  1 
ATOM 7427 N N   . SER E 5 273 ? 121.390 109.299 109.151 1.00 77.05  ? 220 SER R N   1 
ATOM 7428 C CA  . SER E 5 273 ? 120.475 108.233 109.531 1.00 77.00  ? 220 SER R CA  1 
ATOM 7429 C C   . SER E 5 273 ? 119.642 107.715 108.367 1.00 78.33  ? 220 SER R C   1 
ATOM 7430 O O   . SER E 5 273 ? 118.916 106.731 108.538 1.00 83.19  ? 220 SER R O   1 
ATOM 7431 C CB  . SER E 5 273 ? 119.538 108.704 110.648 1.00 76.02  ? 220 SER R CB  1 
ATOM 7432 O OG  . SER E 5 273 ? 118.738 109.793 110.221 1.00 76.52  ? 220 SER R OG  1 
ATOM 7433 N N   . THR E 5 274 ? 119.736 108.338 107.190 1.00 74.37  ? 221 THR R N   1 
ATOM 7434 C CA  . THR E 5 274 ? 119.052 107.811 106.015 1.00 79.42  ? 221 THR R CA  1 
ATOM 7435 C C   . THR E 5 274 ? 119.653 106.497 105.538 1.00 80.58  ? 221 THR R C   1 
ATOM 7436 O O   . THR E 5 274 ? 119.018 105.789 104.748 1.00 81.03  ? 221 THR R O   1 
ATOM 7437 C CB  . THR E 5 274 ? 119.083 108.835 104.879 1.00 80.48  ? 221 THR R CB  1 
ATOM 7438 O OG1 . THR E 5 274 ? 120.440 109.198 104.596 1.00 83.01  ? 221 THR R OG1 1 
ATOM 7439 C CG2 . THR E 5 274 ? 118.300 110.081 105.263 1.00 81.66  ? 221 THR R CG2 1 
ATOM 7440 N N   . LYS E 5 275 ? 120.861 106.159 105.993 1.00 89.09  ? 222 LYS R N   1 
ATOM 7441 C CA  . LYS E 5 275 ? 121.483 104.903 105.588 1.00 90.67  ? 222 LYS R CA  1 
ATOM 7442 C C   . LYS E 5 275 ? 120.798 103.700 106.223 1.00 88.69  ? 222 LYS R C   1 
ATOM 7443 O O   . LYS E 5 275 ? 120.758 102.623 105.617 1.00 87.37  ? 222 LYS R O   1 
ATOM 7444 C CB  . LYS E 5 275 ? 122.967 104.911 105.953 1.00 86.47  ? 222 LYS R CB  1 
ATOM 7445 C CG  . LYS E 5 275 ? 123.755 106.066 105.359 1.00 86.55  ? 222 LYS R CG  1 
ATOM 7446 C CD  . LYS E 5 275 ? 125.203 106.030 105.821 1.00 90.69  ? 222 LYS R CD  1 
ATOM 7447 C CE  . LYS E 5 275 ? 126.001 107.191 105.249 1.00 92.19  ? 222 LYS R CE  1 
ATOM 7448 N NZ  . LYS E 5 275 ? 127.419 107.163 105.703 1.00 91.68  ? 222 LYS R NZ  1 
ATOM 7449 N N   . PHE E 5 276 ? 120.252 103.856 107.433 1.00 77.69  ? 223 PHE R N   1 
ATOM 7450 C CA  . PHE E 5 276 ? 119.713 102.723 108.174 1.00 77.50  ? 223 PHE R CA  1 
ATOM 7451 C C   . PHE E 5 276 ? 118.309 102.961 108.719 1.00 78.01  ? 223 PHE R C   1 
ATOM 7452 O O   . PHE E 5 276 ? 117.803 102.117 109.469 1.00 84.68  ? 223 PHE R O   1 
ATOM 7453 C CB  . PHE E 5 276 ? 120.652 102.345 109.327 1.00 77.82  ? 223 PHE R CB  1 
ATOM 7454 C CG  . PHE E 5 276 ? 121.087 103.513 110.167 1.00 80.57  ? 223 PHE R CG  1 
ATOM 7455 C CD1 . PHE E 5 276 ? 120.291 103.976 111.202 1.00 79.37  ? 223 PHE R CD1 1 
ATOM 7456 C CD2 . PHE E 5 276 ? 122.297 104.144 109.926 1.00 84.10  ? 223 PHE R CD2 1 
ATOM 7457 C CE1 . PHE E 5 276 ? 120.690 105.049 111.977 1.00 81.24  ? 223 PHE R CE1 1 
ATOM 7458 C CE2 . PHE E 5 276 ? 122.702 105.217 110.698 1.00 85.94  ? 223 PHE R CE2 1 
ATOM 7459 C CZ  . PHE E 5 276 ? 121.898 105.670 111.725 1.00 82.77  ? 223 PHE R CZ  1 
ATOM 7460 N N   . ARG E 5 277 ? 117.661 104.071 108.369 1.00 68.14  ? 224 ARG R N   1 
ATOM 7461 C CA  . ARG E 5 277 ? 116.248 104.253 108.705 1.00 68.33  ? 224 ARG R CA  1 
ATOM 7462 C C   . ARG E 5 277 ? 115.385 103.746 107.549 1.00 68.60  ? 224 ARG R C   1 
ATOM 7463 O O   . ARG E 5 277 ? 114.673 104.491 106.873 1.00 74.73  ? 224 ARG R O   1 
ATOM 7464 C CB  . ARG E 5 277 ? 115.954 105.711 109.032 1.00 69.41  ? 224 ARG R CB  1 
ATOM 7465 C CG  . ARG E 5 277 ? 116.412 106.143 110.417 1.00 71.46  ? 224 ARG R CG  1 
ATOM 7466 C CD  . ARG E 5 277 ? 115.934 107.550 110.753 1.00 74.23  ? 224 ARG R CD  1 
ATOM 7467 N NE  . ARG E 5 277 ? 114.492 107.612 110.964 1.00 72.34  ? 224 ARG R NE  1 
ATOM 7468 C CZ  . ARG E 5 277 ? 113.619 108.031 110.059 1.00 73.53  ? 224 ARG R CZ  1 
ATOM 7469 N NH1 . ARG E 5 277 ? 114.007 108.440 108.862 1.00 77.92  ? 224 ARG R NH1 1 
ATOM 7470 N NH2 . ARG E 5 277 ? 112.324 108.040 110.362 1.00 65.84  ? 224 ARG R NH2 1 
ATOM 7471 N N   . LYS E 5 278 ? 115.472 102.447 107.331 1.00 65.65  ? 225 LYS R N   1 
ATOM 7472 C CA  . LYS E 5 278 ? 114.701 101.763 106.311 1.00 69.94  ? 225 LYS R CA  1 
ATOM 7473 C C   . LYS E 5 278 ? 113.484 101.086 106.929 1.00 72.17  ? 225 LYS R C   1 
ATOM 7474 O O   . LYS E 5 278 ? 113.522 100.668 108.090 1.00 72.02  ? 225 LYS R O   1 
ATOM 7475 C CB  . LYS E 5 278 ? 115.561 100.716 105.595 1.00 71.32  ? 225 LYS R CB  1 
ATOM 7476 C CG  . LYS E 5 278 ? 116.748 101.305 104.853 1.00 71.53  ? 225 LYS R CG  1 
ATOM 7477 C CD  . LYS E 5 278 ? 117.551 100.228 104.142 1.00 70.20  ? 225 LYS R CD  1 
ATOM 7478 C CE  . LYS E 5 278 ? 118.723 100.829 103.383 1.00 71.96  ? 225 LYS R CE  1 
ATOM 7479 N NZ  . LYS E 5 278 ? 119.520 99.791  102.674 1.00 74.11  ? 225 LYS R NZ  1 
ATOM 7480 N N   . PRO E 5 279 ? 112.383 100.975 106.184 1.00 66.54  ? 226 PRO R N   1 
ATOM 7481 C CA  . PRO E 5 279 ? 111.234 100.216 106.701 1.00 68.17  ? 226 PRO R CA  1 
ATOM 7482 C C   . PRO E 5 279 ? 111.555 98.761  106.984 1.00 64.91  ? 226 PRO R C   1 
ATOM 7483 O O   . PRO E 5 279 ? 110.966 98.171  107.898 1.00 67.08  ? 226 PRO R O   1 
ATOM 7484 C CB  . PRO E 5 279 ? 110.191 100.357 105.585 1.00 59.52  ? 226 PRO R CB  1 
ATOM 7485 C CG  . PRO E 5 279 ? 110.595 101.580 104.845 1.00 63.96  ? 226 PRO R CG  1 
ATOM 7486 C CD  . PRO E 5 279 ? 112.088 101.612 104.892 1.00 60.74  ? 226 PRO R CD  1 
ATOM 7487 N N   . SER E 5 280 ? 112.467 98.159  106.217 1.00 62.80  ? 227 SER R N   1 
ATOM 7488 C CA  . SER E 5 280 ? 112.884 96.792  106.504 1.00 62.81  ? 227 SER R CA  1 
ATOM 7489 C C   . SER E 5 280 ? 113.635 96.712  107.827 1.00 64.90  ? 227 SER R C   1 
ATOM 7490 O O   . SER E 5 280 ? 113.437 95.770  108.604 1.00 68.47  ? 227 SER R O   1 
ATOM 7491 C CB  . SER E 5 280 ? 113.745 96.254  105.362 1.00 63.70  ? 227 SER R CB  1 
ATOM 7492 O OG  . SER E 5 280 ? 114.902 97.050  105.174 1.00 63.84  ? 227 SER R OG  1 
ATOM 7493 N N   . VAL E 5 281 ? 114.507 97.685  108.094 1.00 65.96  ? 228 VAL R N   1 
ATOM 7494 C CA  . VAL E 5 281 ? 115.232 97.705  109.360 1.00 68.81  ? 228 VAL R CA  1 
ATOM 7495 C C   . VAL E 5 281 ? 114.285 98.003  110.516 1.00 63.70  ? 228 VAL R C   1 
ATOM 7496 O O   . VAL E 5 281 ? 114.420 97.437  111.607 1.00 62.76  ? 228 VAL R O   1 
ATOM 7497 C CB  . VAL E 5 281 ? 116.389 98.719  109.296 1.00 64.02  ? 228 VAL R CB  1 
ATOM 7498 C CG1 . VAL E 5 281 ? 117.190 98.697  110.591 1.00 59.82  ? 228 VAL R CG1 1 
ATOM 7499 C CG2 . VAL E 5 281 ? 117.289 98.425  108.106 1.00 65.34  ? 228 VAL R CG2 1 
ATOM 7500 N N   . ALA E 5 282 ? 113.314 98.895  110.299 1.00 60.05  ? 229 ALA R N   1 
ATOM 7501 C CA  . ALA E 5 282 ? 112.363 99.221  111.358 1.00 63.39  ? 229 ALA R CA  1 
ATOM 7502 C C   . ALA E 5 282 ? 111.535 98.006  111.762 1.00 64.11  ? 229 ALA R C   1 
ATOM 7503 O O   . ALA E 5 282 ? 111.274 97.794  112.952 1.00 63.15  ? 229 ALA R O   1 
ATOM 7504 C CB  . ALA E 5 282 ? 111.454 100.364 110.909 1.00 62.86  ? 229 ALA R CB  1 
ATOM 7505 N N   . THR E 5 283 ? 111.102 97.205  110.786 1.00 66.23  ? 230 THR R N   1 
ATOM 7506 C CA  . THR E 5 283 ? 110.350 95.994  111.101 1.00 65.71  ? 230 THR R CA  1 
ATOM 7507 C C   . THR E 5 283 ? 111.207 94.990  111.861 1.00 68.66  ? 230 THR R C   1 
ATOM 7508 O O   . THR E 5 283 ? 110.726 94.328  112.788 1.00 69.86  ? 230 THR R O   1 
ATOM 7509 C CB  . THR E 5 283 ? 109.796 95.370  109.821 1.00 64.14  ? 230 THR R CB  1 
ATOM 7510 O OG1 . THR E 5 283 ? 109.019 96.345  109.117 1.00 68.28  ? 230 THR R OG1 1 
ATOM 7511 C CG2 . THR E 5 283 ? 108.913 94.173  110.146 1.00 60.27  ? 230 THR R CG2 1 
ATOM 7512 N N   . LEU E 5 284 ? 112.482 94.863  111.484 1.00 68.06  ? 231 LEU R N   1 
ATOM 7513 C CA  . LEU E 5 284 ? 113.373 93.952  112.195 1.00 71.43  ? 231 LEU R CA  1 
ATOM 7514 C C   . LEU E 5 284 ? 113.585 94.401  113.635 1.00 76.91  ? 231 LEU R C   1 
ATOM 7515 O O   . LEU E 5 284 ? 113.649 93.571  114.549 1.00 70.18  ? 231 LEU R O   1 
ATOM 7516 C CB  . LEU E 5 284 ? 114.709 93.845  111.459 1.00 63.39  ? 231 LEU R CB  1 
ATOM 7517 C CG  . LEU E 5 284 ? 115.813 93.029  112.136 1.00 71.60  ? 231 LEU R CG  1 
ATOM 7518 C CD1 . LEU E 5 284 ? 115.389 91.577  112.299 1.00 69.82  ? 231 LEU R CD1 1 
ATOM 7519 C CD2 . LEU E 5 284 ? 117.114 93.126  111.353 1.00 71.54  ? 231 LEU R CD2 1 
ATOM 7520 N N   . VAL E 5 285 ? 113.705 95.713  113.856 1.00 75.18  ? 232 VAL R N   1 
ATOM 7521 C CA  . VAL E 5 285 ? 113.881 96.226  115.212 1.00 67.92  ? 232 VAL R CA  1 
ATOM 7522 C C   . VAL E 5 285 ? 112.655 95.920  116.064 1.00 67.77  ? 232 VAL R C   1 
ATOM 7523 O O   . VAL E 5 285 ? 112.774 95.487  117.217 1.00 70.51  ? 232 VAL R O   1 
ATOM 7524 C CB  . VAL E 5 285 ? 114.193 97.734  115.178 1.00 61.66  ? 232 VAL R CB  1 
ATOM 7525 C CG1 . VAL E 5 285 ? 114.119 98.327  116.576 1.00 65.76  ? 232 VAL R CG1 1 
ATOM 7526 C CG2 . VAL E 5 285 ? 115.571 97.973  114.577 1.00 63.79  ? 232 VAL R CG2 1 
ATOM 7527 N N   . ILE E 5 286 ? 111.458 96.130  115.510 1.00 65.11  ? 233 ILE R N   1 
ATOM 7528 C CA  . ILE E 5 286 ? 110.236 95.886  116.272 1.00 68.53  ? 233 ILE R CA  1 
ATOM 7529 C C   . ILE E 5 286 ? 110.078 94.401  116.576 1.00 69.00  ? 233 ILE R C   1 
ATOM 7530 O O   . ILE E 5 286 ? 109.706 94.018  117.692 1.00 73.30  ? 233 ILE R O   1 
ATOM 7531 C CB  . ILE E 5 286 ? 109.011 96.443  115.524 1.00 58.17  ? 233 ILE R CB  1 
ATOM 7532 C CG1 . ILE E 5 286 ? 109.098 97.967  115.423 1.00 62.37  ? 233 ILE R CG1 1 
ATOM 7533 C CG2 . ILE E 5 286 ? 107.723 96.021  116.218 1.00 60.18  ? 233 ILE R CG2 1 
ATOM 7534 C CD1 . ILE E 5 286 ? 107.860 98.616  114.847 1.00 70.14  ? 233 ILE R CD1 1 
ATOM 7535 N N   . CYS E 5 287 ? 110.360 93.541  115.593 1.00 65.86  ? 234 CYS R N   1 
ATOM 7536 C CA  . CYS E 5 287 ? 110.333 92.104  115.845 1.00 69.94  ? 234 CYS R CA  1 
ATOM 7537 C C   . CYS E 5 287 ? 111.376 91.698  116.877 1.00 74.15  ? 234 CYS R C   1 
ATOM 7538 O O   . CYS E 5 287 ? 111.183 90.713  117.599 1.00 75.69  ? 234 CYS R O   1 
ATOM 7539 C CB  . CYS E 5 287 ? 110.542 91.334  114.540 1.00 74.05  ? 234 CYS R CB  1 
ATOM 7540 S SG  . CYS E 5 287 ? 109.204 91.527  113.338 1.00 84.23  ? 234 CYS R SG  1 
ATOM 7541 N N   . LEU E 5 288 ? 112.485 92.435  116.961 1.00 77.65  ? 235 LEU R N   1 
ATOM 7542 C CA  . LEU E 5 288 ? 113.468 92.158  118.001 1.00 80.43  ? 235 LEU R CA  1 
ATOM 7543 C C   . LEU E 5 288 ? 112.967 92.605  119.368 1.00 80.73  ? 235 LEU R C   1 
ATOM 7544 O O   . LEU E 5 288 ? 113.324 92.002  120.387 1.00 80.41  ? 235 LEU R O   1 
ATOM 7545 C CB  . LEU E 5 288 ? 114.794 92.842  117.665 1.00 83.13  ? 235 LEU R CB  1 
ATOM 7546 C CG  . LEU E 5 288 ? 115.971 92.590  118.610 1.00 83.73  ? 235 LEU R CG  1 
ATOM 7547 C CD1 . LEU E 5 288 ? 116.277 91.103  118.696 1.00 82.25  ? 235 LEU R CD1 1 
ATOM 7548 C CD2 . LEU E 5 288 ? 117.198 93.371  118.165 1.00 80.72  ? 235 LEU R CD2 1 
ATOM 7549 N N   . LEU E 5 289 ? 112.145 93.658  119.410 1.00 72.21  ? 236 LEU R N   1 
ATOM 7550 C CA  . LEU E 5 289 ? 111.588 94.122  120.678 1.00 68.53  ? 236 LEU R CA  1 
ATOM 7551 C C   . LEU E 5 289 ? 110.634 93.095  121.274 1.00 67.00  ? 236 LEU R C   1 
ATOM 7552 O O   . LEU E 5 289 ? 110.621 92.886  122.493 1.00 65.95  ? 236 LEU R O   1 
ATOM 7553 C CB  . LEU E 5 289 ? 110.879 95.462  120.481 1.00 66.50  ? 236 LEU R CB  1 
ATOM 7554 C CG  . LEU E 5 289 ? 111.755 96.644  120.060 1.00 64.68  ? 236 LEU R CG  1 
ATOM 7555 C CD1 . LEU E 5 289 ? 110.922 97.909  119.917 1.00 61.25  ? 236 LEU R CD1 1 
ATOM 7556 C CD2 . LEU E 5 289 ? 112.888 96.856  121.056 1.00 68.57  ? 236 LEU R CD2 1 
ATOM 7557 N N   . TRP E 5 290 ? 109.819 92.452  120.432 1.00 67.20  ? 237 TRP R N   1 
ATOM 7558 C CA  . TRP E 5 290 ? 108.940 91.390  120.912 1.00 68.89  ? 237 TRP R CA  1 
ATOM 7559 C C   . TRP E 5 290 ? 109.737 90.237  121.507 1.00 71.56  ? 237 TRP R C   1 
ATOM 7560 O O   . TRP E 5 290 ? 109.357 89.682  122.545 1.00 75.02  ? 237 TRP R O   1 
ATOM 7561 C CB  . TRP E 5 290 ? 108.047 90.889  119.778 1.00 68.95  ? 237 TRP R CB  1 
ATOM 7562 C CG  . TRP E 5 290 ? 106.911 91.805  119.454 1.00 67.29  ? 237 TRP R CG  1 
ATOM 7563 C CD1 . TRP E 5 290 ? 106.956 92.926  118.679 1.00 69.89  ? 237 TRP R CD1 1 
ATOM 7564 C CD2 . TRP E 5 290 ? 105.555 91.675  119.894 1.00 65.50  ? 237 TRP R CD2 1 
ATOM 7565 N NE1 . TRP E 5 290 ? 105.712 93.504  118.610 1.00 69.30  ? 237 TRP R NE1 1 
ATOM 7566 C CE2 . TRP E 5 290 ? 104.834 92.755  119.348 1.00 66.54  ? 237 TRP R CE2 1 
ATOM 7567 C CE3 . TRP E 5 290 ? 104.882 90.751  120.698 1.00 69.47  ? 237 TRP R CE3 1 
ATOM 7568 C CZ2 . TRP E 5 290 ? 103.474 92.935  119.579 1.00 68.18  ? 237 TRP R CZ2 1 
ATOM 7569 C CZ3 . TRP E 5 290 ? 103.532 90.932  120.927 1.00 68.70  ? 237 TRP R CZ3 1 
ATOM 7570 C CH2 . TRP E 5 290 ? 102.842 92.015  120.370 1.00 73.02  ? 237 TRP R CH2 1 
ATOM 7571 N N   . ALA E 5 291 ? 110.838 89.853  120.857 1.00 79.88  ? 238 ALA R N   1 
ATOM 7572 C CA  . ALA E 5 291 ? 111.669 88.780  121.391 1.00 84.85  ? 238 ALA R CA  1 
ATOM 7573 C C   . ALA E 5 291 ? 112.255 89.165  122.742 1.00 83.96  ? 238 ALA R C   1 
ATOM 7574 O O   . ALA E 5 291 ? 112.275 88.351  123.674 1.00 84.58  ? 238 ALA R O   1 
ATOM 7575 C CB  . ALA E 5 291 ? 112.778 88.432  120.399 1.00 85.33  ? 238 ALA R CB  1 
ATOM 7576 N N   . LEU E 5 292 ? 112.742 90.401  122.868 1.00 84.39  ? 239 LEU R N   1 
ATOM 7577 C CA  . LEU E 5 292 ? 113.240 90.868  124.157 1.00 84.96  ? 239 LEU R CA  1 
ATOM 7578 C C   . LEU E 5 292 ? 112.117 90.997  125.178 1.00 86.47  ? 239 LEU R C   1 
ATOM 7579 O O   . LEU E 5 292 ? 112.342 90.777  126.374 1.00 90.92  ? 239 LEU R O   1 
ATOM 7580 C CB  . LEU E 5 292 ? 113.965 92.203  123.995 1.00 85.27  ? 239 LEU R CB  1 
ATOM 7581 C CG  . LEU E 5 292 ? 115.265 92.186  123.188 1.00 88.68  ? 239 LEU R CG  1 
ATOM 7582 C CD1 . LEU E 5 292 ? 115.893 93.571  123.157 1.00 88.08  ? 239 LEU R CD1 1 
ATOM 7583 C CD2 . LEU E 5 292 ? 116.239 91.166  123.759 1.00 84.61  ? 239 LEU R CD2 1 
ATOM 7584 N N   . SER E 5 293 ? 110.910 91.358  124.733 1.00 85.93  ? 240 SER R N   1 
ATOM 7585 C CA  . SER E 5 293 ? 109.783 91.445  125.657 1.00 89.14  ? 240 SER R CA  1 
ATOM 7586 C C   . SER E 5 293 ? 109.434 90.077  126.228 1.00 90.61  ? 240 SER R C   1 
ATOM 7587 O O   . SER E 5 293 ? 109.128 89.954  127.420 1.00 90.76  ? 240 SER R O   1 
ATOM 7588 C CB  . SER E 5 293 ? 108.573 92.059  124.955 1.00 88.98  ? 240 SER R CB  1 
ATOM 7589 O OG  . SER E 5 293 ? 107.456 92.117  125.825 1.00 92.95  ? 240 SER R OG  1 
ATOM 7590 N N   . PHE E 5 294 ? 109.459 89.039  125.388 1.00 83.68  ? 241 PHE R N   1 
ATOM 7591 C CA  . PHE E 5 294 ? 109.171 87.692  125.870 1.00 79.91  ? 241 PHE R CA  1 
ATOM 7592 C C   . PHE E 5 294 ? 110.192 87.253  126.912 1.00 83.47  ? 241 PHE R C   1 
ATOM 7593 O O   . PHE E 5 294 ? 109.841 86.594  127.898 1.00 86.78  ? 241 PHE R O   1 
ATOM 7594 C CB  . PHE E 5 294 ? 109.131 86.710  124.700 1.00 80.84  ? 241 PHE R CB  1 
ATOM 7595 C CG  . PHE E 5 294 ? 107.830 86.718  123.949 1.00 85.37  ? 241 PHE R CG  1 
ATOM 7596 C CD1 . PHE E 5 294 ? 106.657 87.105  124.577 1.00 84.26  ? 241 PHE R CD1 1 
ATOM 7597 C CD2 . PHE E 5 294 ? 107.777 86.335  122.620 1.00 85.84  ? 241 PHE R CD2 1 
ATOM 7598 C CE1 . PHE E 5 294 ? 105.457 87.113  123.892 1.00 84.35  ? 241 PHE R CE1 1 
ATOM 7599 C CE2 . PHE E 5 294 ? 106.579 86.340  121.929 1.00 84.57  ? 241 PHE R CE2 1 
ATOM 7600 C CZ  . PHE E 5 294 ? 105.418 86.730  122.566 1.00 83.52  ? 241 PHE R CZ  1 
ATOM 7601 N N   . ILE E 5 295 ? 111.464 87.595  126.702 1.00 85.70  ? 242 ILE R N   1 
ATOM 7602 C CA  . ILE E 5 295 ? 112.491 87.270  127.685 1.00 87.17  ? 242 ILE R CA  1 
ATOM 7603 C C   . ILE E 5 295 ? 112.256 88.044  128.976 1.00 88.12  ? 242 ILE R C   1 
ATOM 7604 O O   . ILE E 5 295 ? 112.499 87.534  130.077 1.00 90.56  ? 242 ILE R O   1 
ATOM 7605 C CB  . ILE E 5 295 ? 113.891 87.539  127.104 1.00 83.87  ? 242 ILE R CB  1 
ATOM 7606 C CG1 . ILE E 5 295 ? 114.090 86.741  125.813 1.00 86.11  ? 242 ILE R CG1 1 
ATOM 7607 C CG2 . ILE E 5 295 ? 114.972 87.190  128.115 1.00 83.43  ? 242 ILE R CG2 1 
ATOM 7608 C CD1 . ILE E 5 295 ? 115.440 86.951  125.165 1.00 89.60  ? 242 ILE R CD1 1 
ATOM 7609 N N   . SER E 5 296 ? 111.769 89.281  128.867 1.00 89.37  ? 243 SER R N   1 
ATOM 7610 C CA  . SER E 5 296 ? 111.569 90.121  130.040 1.00 88.95  ? 243 SER R CA  1 
ATOM 7611 C C   . SER E 5 296 ? 110.326 89.745  130.834 1.00 89.29  ? 243 SER R C   1 
ATOM 7612 O O   . SER E 5 296 ? 110.176 90.208  131.969 1.00 91.54  ? 243 SER R O   1 
ATOM 7613 C CB  . SER E 5 296 ? 111.486 91.593  129.627 1.00 88.27  ? 243 SER R CB  1 
ATOM 7614 O OG  . SER E 5 296 ? 110.336 91.840  128.836 1.00 90.97  ? 243 SER R OG  1 
ATOM 7615 N N   . ILE E 5 297 ? 109.437 88.928  130.273 1.00 95.12  ? 244 ILE R N   1 
ATOM 7616 C CA  . ILE E 5 297 ? 108.251 88.457  130.976 1.00 97.09  ? 244 ILE R CA  1 
ATOM 7617 C C   . ILE E 5 297 ? 108.396 87.003  131.401 1.00 101.80 ? 244 ILE R C   1 
ATOM 7618 O O   . ILE E 5 297 ? 107.424 86.399  131.868 1.00 104.70 ? 244 ILE R O   1 
ATOM 7619 C CB  . ILE E 5 297 ? 106.982 88.644  130.130 1.00 94.53  ? 244 ILE R CB  1 
ATOM 7620 C CG1 . ILE E 5 297 ? 107.027 87.726  128.907 1.00 96.78  ? 244 ILE R CG1 1 
ATOM 7621 C CG2 . ILE E 5 297 ? 106.832 90.097  129.710 1.00 95.62  ? 244 ILE R CG2 1 
ATOM 7622 C CD1 . ILE E 5 297 ? 105.691 87.526  128.238 1.00 97.57  ? 244 ILE R CD1 1 
ATOM 7623 N N   . THR E 5 298 ? 109.583 86.421  131.237 1.00 115.93 ? 245 THR R N   1 
ATOM 7624 C CA  . THR E 5 298 ? 109.786 85.024  131.617 1.00 117.67 ? 245 THR R CA  1 
ATOM 7625 C C   . THR E 5 298 ? 109.516 84.769  133.096 1.00 118.23 ? 245 THR R C   1 
ATOM 7626 O O   . THR E 5 298 ? 108.823 83.785  133.409 1.00 118.41 ? 245 THR R O   1 
ATOM 7627 C CB  . THR E 5 298 ? 111.198 84.580  131.212 1.00 116.35 ? 245 THR R CB  1 
ATOM 7628 O OG1 . THR E 5 298 ? 111.374 84.768  129.803 1.00 116.92 ? 245 THR R OG1 1 
ATOM 7629 C CG2 . THR E 5 298 ? 111.414 83.113  131.547 1.00 116.25 ? 245 THR R CG2 1 
ATOM 7630 N N   . PRO E 5 299 ? 110.004 85.580  134.044 1.00 116.69 ? 246 PRO R N   1 
ATOM 7631 C CA  . PRO E 5 299 ? 109.632 85.350  135.450 1.00 117.93 ? 246 PRO R CA  1 
ATOM 7632 C C   . PRO E 5 299 ? 108.146 85.500  135.729 1.00 118.71 ? 246 PRO R C   1 
ATOM 7633 O O   . PRO E 5 299 ? 107.668 84.968  136.739 1.00 121.83 ? 246 PRO R O   1 
ATOM 7634 C CB  . PRO E 5 299 ? 110.448 86.405  136.209 1.00 117.56 ? 246 PRO R CB  1 
ATOM 7635 C CG  . PRO E 5 299 ? 111.583 86.724  135.309 1.00 117.71 ? 246 PRO R CG  1 
ATOM 7636 C CD  . PRO E 5 299 ? 111.009 86.653  133.930 1.00 115.21 ? 246 PRO R CD  1 
ATOM 7637 N N   . VAL E 5 300 ? 107.400 86.208  134.878 1.00 114.87 ? 247 VAL R N   1 
ATOM 7638 C CA  . VAL E 5 300 ? 105.983 86.437  135.150 1.00 115.75 ? 247 VAL R CA  1 
ATOM 7639 C C   . VAL E 5 300 ? 105.191 85.140  135.022 1.00 116.86 ? 247 VAL R C   1 
ATOM 7640 O O   . VAL E 5 300 ? 104.384 84.801  135.894 1.00 117.65 ? 247 VAL R O   1 
ATOM 7641 C CB  . VAL E 5 300 ? 105.427 87.530  134.220 1.00 115.04 ? 247 VAL R CB  1 
ATOM 7642 C CG1 . VAL E 5 300 ? 103.939 87.731  134.467 1.00 113.57 ? 247 VAL R CG1 1 
ATOM 7643 C CG2 . VAL E 5 300 ? 106.186 88.833  134.417 1.00 116.43 ? 247 VAL R CG2 1 
ATOM 7644 N N   . TRP E 5 301 ? 105.411 84.392  133.940 1.00 125.47 ? 248 TRP R N   1 
ATOM 7645 C CA  . TRP E 5 301 ? 104.631 83.183  133.702 1.00 127.36 ? 248 TRP R CA  1 
ATOM 7646 C C   . TRP E 5 301 ? 105.238 81.945  134.346 1.00 127.57 ? 248 TRP R C   1 
ATOM 7647 O O   . TRP E 5 301 ? 104.549 80.925  134.463 1.00 126.67 ? 248 TRP R O   1 
ATOM 7648 C CB  . TRP E 5 301 ? 104.452 82.948  132.198 1.00 126.88 ? 248 TRP R CB  1 
ATOM 7649 C CG  . TRP E 5 301 ? 105.694 82.546  131.470 1.00 127.82 ? 248 TRP R CG  1 
ATOM 7650 C CD1 . TRP E 5 301 ? 106.663 83.372  130.982 1.00 123.87 ? 248 TRP R CD1 1 
ATOM 7651 C CD2 . TRP E 5 301 ? 106.081 81.215  131.108 1.00 130.54 ? 248 TRP R CD2 1 
ATOM 7652 N NE1 . TRP E 5 301 ? 107.642 82.636  130.358 1.00 124.50 ? 248 TRP R NE1 1 
ATOM 7653 C CE2 . TRP E 5 301 ? 107.306 81.309  130.420 1.00 128.30 ? 248 TRP R CE2 1 
ATOM 7654 C CE3 . TRP E 5 301 ? 105.514 79.953  131.308 1.00 128.65 ? 248 TRP R CE3 1 
ATOM 7655 C CZ2 . TRP E 5 301 ? 107.975 80.188  129.931 1.00 127.29 ? 248 TRP R CZ2 1 
ATOM 7656 C CZ3 . TRP E 5 301 ? 106.179 78.842  130.822 1.00 126.31 ? 248 TRP R CZ3 1 
ATOM 7657 C CH2 . TRP E 5 301 ? 107.396 78.967  130.142 1.00 126.89 ? 248 TRP R CH2 1 
ATOM 7658 N N   . LEU E 5 302 ? 106.505 82.005  134.764 1.00 129.93 ? 249 LEU R N   1 
ATOM 7659 C CA  . LEU E 5 302 ? 107.090 80.912  135.530 1.00 130.89 ? 249 LEU R CA  1 
ATOM 7660 C C   . LEU E 5 302 ? 106.517 80.821  136.938 1.00 130.70 ? 249 LEU R C   1 
ATOM 7661 O O   . LEU E 5 302 ? 106.595 79.755  137.557 1.00 131.16 ? 249 LEU R O   1 
ATOM 7662 C CB  . LEU E 5 302 ? 108.611 81.063  135.599 1.00 129.74 ? 249 LEU R CB  1 
ATOM 7663 C CG  . LEU E 5 302 ? 109.393 80.762  134.319 1.00 129.62 ? 249 LEU R CG  1 
ATOM 7664 C CD1 . LEU E 5 302 ? 110.884 80.952  134.548 1.00 130.46 ? 249 LEU R CD1 1 
ATOM 7665 C CD2 . LEU E 5 302 ? 109.098 79.354  133.827 1.00 129.55 ? 249 LEU R CD2 1 
ATOM 7666 N N   . TYR E 5 303 ? 105.944 81.910  137.455 1.00 134.61 ? 250 TYR R N   1 
ATOM 7667 C CA  . TYR E 5 303 ? 105.474 81.959  138.834 1.00 136.51 ? 250 TYR R CA  1 
ATOM 7668 C C   . TYR E 5 303 ? 104.005 82.352  138.936 1.00 136.60 ? 250 TYR R C   1 
ATOM 7669 O O   . TYR E 5 303 ? 103.510 82.560  140.049 1.00 137.51 ? 250 TYR R O   1 
ATOM 7670 C CB  . TYR E 5 303 ? 106.326 82.934  139.655 1.00 134.22 ? 250 TYR R CB  1 
ATOM 7671 C CG  . TYR E 5 303 ? 107.807 82.624  139.643 1.00 134.76 ? 250 TYR R CG  1 
ATOM 7672 C CD1 . TYR E 5 303 ? 108.267 81.323  139.797 1.00 136.72 ? 250 TYR R CD1 1 
ATOM 7673 C CD2 . TYR E 5 303 ? 108.744 83.634  139.474 1.00 135.67 ? 250 TYR R CD2 1 
ATOM 7674 C CE1 . TYR E 5 303 ? 109.621 81.038  139.784 1.00 136.89 ? 250 TYR R CE1 1 
ATOM 7675 C CE2 . TYR E 5 303 ? 110.098 83.359  139.460 1.00 137.14 ? 250 TYR R CE2 1 
ATOM 7676 C CZ  . TYR E 5 303 ? 110.531 82.060  139.615 1.00 137.58 ? 250 TYR R CZ  1 
ATOM 7677 O OH  . TYR E 5 303 ? 111.878 81.781  139.602 1.00 138.04 ? 250 TYR R OH  1 
ATOM 7678 N N   . ALA E 5 304 ? 103.298 82.459  137.813 1.00 135.12 ? 251 ALA R N   1 
ATOM 7679 C CA  . ALA E 5 304 ? 101.885 82.831  137.814 1.00 135.24 ? 251 ALA R CA  1 
ATOM 7680 C C   . ALA E 5 304 ? 101.048 81.588  138.084 1.00 137.84 ? 251 ALA R C   1 
ATOM 7681 O O   . ALA E 5 304 ? 100.747 80.814  137.172 1.00 137.91 ? 251 ALA R O   1 
ATOM 7682 C CB  . ALA E 5 304 ? 101.499 83.480  136.490 1.00 135.11 ? 251 ALA R CB  1 
ATOM 7683 N N   . ARG E 5 305 ? 100.669 81.392  139.344 1.00 144.86 ? 252 ARG R N   1 
ATOM 7684 C CA  . ARG E 5 305 ? 99.893  80.237  139.769 1.00 143.59 ? 252 ARG R CA  1 
ATOM 7685 C C   . ARG E 5 305 ? 98.685  80.702  140.571 1.00 143.66 ? 252 ARG R C   1 
ATOM 7686 O O   . ARG E 5 305 ? 98.574  81.869  140.955 1.00 143.91 ? 252 ARG R O   1 
ATOM 7687 C CB  . ARG E 5 305 ? 100.743 79.267  140.603 1.00 141.26 ? 252 ARG R CB  1 
ATOM 7688 C CG  . ARG E 5 305 ? 101.987 78.753  139.897 1.00 141.07 ? 252 ARG R CG  1 
ATOM 7689 C CD  . ARG E 5 305 ? 101.629 78.010  138.621 1.00 142.07 ? 252 ARG R CD  1 
ATOM 7690 N NE  . ARG E 5 305 ? 102.812 77.563  137.896 1.00 142.89 ? 252 ARG R NE  1 
ATOM 7691 C CZ  . ARG E 5 305 ? 102.782 76.924  136.735 1.00 142.92 ? 252 ARG R CZ  1 
ATOM 7692 N NH1 . ARG E 5 305 ? 101.640 76.637  136.133 1.00 140.54 ? 252 ARG R NH1 1 
ATOM 7693 N NH2 . ARG E 5 305 ? 103.928 76.563  136.163 1.00 143.93 ? 252 ARG R NH2 1 
ATOM 7694 N N   . LEU E 5 306 ? 97.771  79.768  140.818 1.00 145.06 ? 253 LEU R N   1 
ATOM 7695 C CA  . LEU E 5 306 ? 96.613  80.050  141.654 1.00 146.04 ? 253 LEU R CA  1 
ATOM 7696 C C   . LEU E 5 306 ? 97.031  80.208  143.111 1.00 146.69 ? 253 LEU R C   1 
ATOM 7697 O O   . LEU E 5 306 ? 97.984  79.580  143.581 1.00 145.85 ? 253 LEU R O   1 
ATOM 7698 C CB  . LEU E 5 306 ? 95.574  78.936  141.529 1.00 144.71 ? 253 LEU R CB  1 
ATOM 7699 C CG  . LEU E 5 306 ? 94.844  78.812  140.190 1.00 143.68 ? 253 LEU R CG  1 
ATOM 7700 C CD1 . LEU E 5 306 ? 93.844  77.667  140.236 1.00 143.77 ? 253 LEU R CD1 1 
ATOM 7701 C CD2 . LEU E 5 306 ? 94.152  80.117  139.832 1.00 143.82 ? 253 LEU R CD2 1 
ATOM 7702 N N   . ILE E 5 307 ? 96.308  81.060  143.829 1.00 153.56 ? 254 ILE R N   1 
ATOM 7703 C CA  . ILE E 5 307 ? 96.592  81.360  145.224 1.00 152.65 ? 254 ILE R CA  1 
ATOM 7704 C C   . ILE E 5 307 ? 95.346  81.039  146.040 1.00 152.49 ? 254 ILE R C   1 
ATOM 7705 O O   . ILE E 5 307 ? 94.272  81.583  145.768 1.00 151.72 ? 254 ILE R O   1 
ATOM 7706 C CB  . ILE E 5 307 ? 97.010  82.826  145.430 1.00 152.40 ? 254 ILE R CB  1 
ATOM 7707 C CG1 . ILE E 5 307 ? 98.324  83.116  144.703 1.00 152.22 ? 254 ILE R CG1 1 
ATOM 7708 C CG2 . ILE E 5 307 ? 97.135  83.141  146.914 1.00 152.24 ? 254 ILE R CG2 1 
ATOM 7709 C CD1 . ILE E 5 307 ? 98.830  84.527  144.902 1.00 152.72 ? 254 ILE R CD1 1 
ATOM 7710 N N   . PRO E 5 308 ? 95.434  80.166  147.044 1.00 161.92 ? 255 PRO R N   1 
ATOM 7711 C CA  . PRO E 5 308 ? 94.280  79.878  147.906 1.00 161.98 ? 255 PRO R CA  1 
ATOM 7712 C C   . PRO E 5 308 ? 94.097  80.953  148.967 1.00 162.89 ? 255 PRO R C   1 
ATOM 7713 O O   . PRO E 5 308 ? 94.890  81.065  149.907 1.00 162.82 ? 255 PRO R O   1 
ATOM 7714 C CB  . PRO E 5 308 ? 94.641  78.519  148.522 1.00 161.75 ? 255 PRO R CB  1 
ATOM 7715 C CG  . PRO E 5 308 ? 96.132  78.504  148.533 1.00 161.92 ? 255 PRO R CG  1 
ATOM 7716 C CD  . PRO E 5 308 ? 96.575  79.275  147.320 1.00 162.40 ? 255 PRO R CD  1 
ATOM 7717 N N   . PHE E 5 309 ? 93.048  81.749  148.816 1.00 172.48 ? 256 PHE R N   1 
ATOM 7718 C CA  . PHE E 5 309 ? 92.704  82.753  149.808 1.00 172.35 ? 256 PHE R CA  1 
ATOM 7719 C C   . PHE E 5 309 ? 91.850  82.136  150.906 1.00 172.84 ? 256 PHE R C   1 
ATOM 7720 O O   . PHE E 5 309 ? 91.287  81.051  150.731 1.00 173.00 ? 256 PHE R O   1 
ATOM 7721 C CB  . PHE E 5 309 ? 91.956  83.909  149.145 1.00 171.67 ? 256 PHE R CB  1 
ATOM 7722 C CG  . PHE E 5 309 ? 92.799  84.717  148.203 1.00 172.56 ? 256 PHE R CG  1 
ATOM 7723 C CD1 . PHE E 5 309 ? 93.548  85.785  148.669 1.00 172.15 ? 256 PHE R CD1 1 
ATOM 7724 C CD2 . PHE E 5 309 ? 92.844  84.412  146.853 1.00 171.65 ? 256 PHE R CD2 1 
ATOM 7725 C CE1 . PHE E 5 309 ? 94.326  86.534  147.807 1.00 171.50 ? 256 PHE R CE1 1 
ATOM 7726 C CE2 . PHE E 5 309 ? 93.621  85.158  145.987 1.00 170.84 ? 256 PHE R CE2 1 
ATOM 7727 C CZ  . PHE E 5 309 ? 94.362  86.219  146.465 1.00 171.27 ? 256 PHE R CZ  1 
ATOM 7728 N N   . PRO E 5 310 ? 91.755  82.789  152.067 1.00 177.86 ? 257 PRO R N   1 
ATOM 7729 C CA  . PRO E 5 310 ? 90.874  82.276  153.122 1.00 179.04 ? 257 PRO R CA  1 
ATOM 7730 C C   . PRO E 5 310 ? 89.447  82.123  152.617 1.00 179.03 ? 257 PRO R C   1 
ATOM 7731 O O   . PRO E 5 310 ? 88.920  82.987  151.913 1.00 178.57 ? 257 PRO R O   1 
ATOM 7732 C CB  . PRO E 5 310 ? 90.978  83.342  154.217 1.00 177.64 ? 257 PRO R CB  1 
ATOM 7733 C CG  . PRO E 5 310 ? 92.335  83.923  154.027 1.00 177.04 ? 257 PRO R CG  1 
ATOM 7734 C CD  . PRO E 5 310 ? 92.582  83.914  152.541 1.00 176.57 ? 257 PRO R CD  1 
ATOM 7735 N N   . GLY E 5 311 ? 88.824  81.012  152.986 1.00 181.94 ? 258 GLY R N   1 
ATOM 7736 C CA  . GLY E 5 311 ? 87.532  80.662  152.435 1.00 181.27 ? 258 GLY R CA  1 
ATOM 7737 C C   . GLY E 5 311 ? 87.664  79.769  151.217 1.00 181.08 ? 258 GLY R C   1 
ATOM 7738 O O   . GLY E 5 311 ? 88.714  79.181  150.940 1.00 180.57 ? 258 GLY R O   1 
ATOM 7739 N N   . GLY E 5 312 ? 86.566  79.670  150.476 1.00 180.66 ? 259 GLY R N   1 
ATOM 7740 C CA  . GLY E 5 312 ? 86.510  78.860  149.279 1.00 180.88 ? 259 GLY R CA  1 
ATOM 7741 C C   . GLY E 5 312 ? 86.949  79.555  148.010 1.00 181.15 ? 259 GLY R C   1 
ATOM 7742 O O   . GLY E 5 312 ? 86.799  78.985  146.924 1.00 180.74 ? 259 GLY R O   1 
ATOM 7743 N N   . ALA E 5 313 ? 87.486  80.767  148.107 1.00 171.38 ? 260 ALA R N   1 
ATOM 7744 C CA  . ALA E 5 313 ? 87.854  81.560  146.944 1.00 170.40 ? 260 ALA R CA  1 
ATOM 7745 C C   . ALA E 5 313 ? 89.344  81.429  146.657 1.00 169.56 ? 260 ALA R C   1 
ATOM 7746 O O   . ALA E 5 313 ? 90.166  81.407  147.577 1.00 169.03 ? 260 ALA R O   1 
ATOM 7747 C CB  . ALA E 5 313 ? 87.493  83.031  147.154 1.00 169.30 ? 260 ALA R CB  1 
ATOM 7748 N N   . VAL E 5 314 ? 89.683  81.342  145.371 1.00 158.82 ? 261 VAL R N   1 
ATOM 7749 C CA  . VAL E 5 314 ? 91.064  81.347  144.913 1.00 158.64 ? 261 VAL R CA  1 
ATOM 7750 C C   . VAL E 5 314 ? 91.239  82.480  143.910 1.00 158.64 ? 261 VAL R C   1 
ATOM 7751 O O   . VAL E 5 314 ? 90.276  82.975  143.318 1.00 158.73 ? 261 VAL R O   1 
ATOM 7752 C CB  . VAL E 5 314 ? 91.480  79.998  144.290 1.00 158.25 ? 261 VAL R CB  1 
ATOM 7753 C CG1 . VAL E 5 314 ? 91.421  78.892  145.332 1.00 157.33 ? 261 VAL R CG1 1 
ATOM 7754 C CG2 . VAL E 5 314 ? 90.591  79.667  143.101 1.00 157.17 ? 261 VAL R CG2 1 
ATOM 7755 N N   . GLY E 5 315 ? 92.485  82.889  143.722 1.00 154.55 ? 262 GLY R N   1 
ATOM 7756 C CA  . GLY E 5 315 ? 92.786  83.991  142.824 1.00 153.47 ? 262 GLY R CA  1 
ATOM 7757 C C   . GLY E 5 315 ? 94.101  83.776  142.111 1.00 153.43 ? 262 GLY R C   1 
ATOM 7758 O O   . GLY E 5 315 ? 95.023  83.148  142.640 1.00 154.03 ? 262 GLY R O   1 
ATOM 7759 N N   . CYS E 5 316 ? 94.182  84.307  140.894 1.00 145.18 ? 263 CYS R N   1 
ATOM 7760 C CA  . CYS E 5 316 ? 95.423  84.275  140.133 1.00 144.71 ? 263 CYS R CA  1 
ATOM 7761 C C   . CYS E 5 316 ? 96.437  85.253  140.714 1.00 144.28 ? 263 CYS R C   1 
ATOM 7762 O O   . CYS E 5 316 ? 96.108  86.399  141.034 1.00 143.08 ? 263 CYS R O   1 
ATOM 7763 C CB  . CYS E 5 316 ? 95.145  84.608  138.668 1.00 144.26 ? 263 CYS R CB  1 
ATOM 7764 S SG  . CYS E 5 316 ? 96.555  84.442  137.555 1.00 143.65 ? 263 CYS R SG  1 
ATOM 7765 N N   . GLY E 5 317 ? 97.675  84.796  140.850 1.00 146.21 ? 264 GLY R N   1 
ATOM 7766 C CA  . GLY E 5 317 ? 98.702  85.632  141.435 1.00 145.91 ? 264 GLY R CA  1 
ATOM 7767 C C   . GLY E 5 317 ? 100.083 85.077  141.170 1.00 146.84 ? 264 GLY R C   1 
ATOM 7768 O O   . GLY E 5 317 ? 100.262 84.150  140.378 1.00 146.50 ? 264 GLY R O   1 
ATOM 7769 N N   . ILE E 5 318 ? 101.063 85.664  141.852 1.00 136.62 ? 265 ILE R N   1 
ATOM 7770 C CA  . ILE E 5 318 ? 102.469 85.300  141.705 1.00 135.51 ? 265 ILE R CA  1 
ATOM 7771 C C   . ILE E 5 318 ? 102.909 84.588  142.977 1.00 135.25 ? 265 ILE R C   1 
ATOM 7772 O O   . ILE E 5 318 ? 102.789 85.139  144.079 1.00 132.66 ? 265 ILE R O   1 
ATOM 7773 C CB  . ILE E 5 318 ? 103.347 86.529  141.428 1.00 134.02 ? 265 ILE R CB  1 
ATOM 7774 C CG1 . ILE E 5 318 ? 102.863 87.258  140.173 1.00 133.27 ? 265 ILE R CG1 1 
ATOM 7775 C CG2 . ILE E 5 318 ? 104.803 86.118  141.278 1.00 134.20 ? 265 ILE R CG2 1 
ATOM 7776 C CD1 . ILE E 5 318 ? 102.886 86.405  138.924 1.00 133.19 ? 265 ILE R CD1 1 
ATOM 7777 N N   . ARG E 5 319 ? 103.417 83.369  142.826 1.00 140.44 ? 266 ARG R N   1 
ATOM 7778 C CA  . ARG E 5 319 ? 103.922 82.567  143.940 1.00 139.70 ? 266 ARG R CA  1 
ATOM 7779 C C   . ARG E 5 319 ? 105.432 82.404  143.773 1.00 140.79 ? 266 ARG R C   1 
ATOM 7780 O O   . ARG E 5 319 ? 105.904 81.435  143.175 1.00 141.05 ? 266 ARG R O   1 
ATOM 7781 C CB  . ARG E 5 319 ? 103.218 81.213  144.001 1.00 138.02 ? 266 ARG R CB  1 
ATOM 7782 C CG  . ARG E 5 319 ? 101.922 81.221  144.793 1.00 139.43 ? 266 ARG R CG  1 
ATOM 7783 C CD  . ARG E 5 319 ? 101.400 79.810  145.005 1.00 139.81 ? 266 ARG R CD  1 
ATOM 7784 N NE  . ARG E 5 319 ? 100.421 79.748  146.084 1.00 141.32 ? 266 ARG R NE  1 
ATOM 7785 C CZ  . ARG E 5 319 ? 100.728 79.576  147.362 1.00 140.55 ? 266 ARG R CZ  1 
ATOM 7786 N NH1 . ARG E 5 319 ? 101.983 79.442  147.760 1.00 140.80 ? 266 ARG R NH1 1 
ATOM 7787 N NH2 . ARG E 5 319 ? 99.752  79.538  148.265 1.00 139.67 ? 266 ARG R NH2 1 
ATOM 7788 N N   . LEU E 5 320 ? 106.187 83.362  144.304 1.00 149.70 ? 267 LEU R N   1 
ATOM 7789 C CA  . LEU E 5 320 ? 107.636 83.275  144.251 1.00 150.39 ? 267 LEU R CA  1 
ATOM 7790 C C   . LEU E 5 320 ? 108.134 82.148  145.155 1.00 151.38 ? 267 LEU R C   1 
ATOM 7791 O O   . LEU E 5 320 ? 107.540 81.871  146.201 1.00 151.94 ? 267 LEU R O   1 
ATOM 7792 C CB  . LEU E 5 320 ? 108.266 84.599  144.676 1.00 150.26 ? 267 LEU R CB  1 
ATOM 7793 C CG  . LEU E 5 320 ? 107.881 85.830  143.854 1.00 150.03 ? 267 LEU R CG  1 
ATOM 7794 C CD1 . LEU E 5 320 ? 108.449 87.093  144.483 1.00 149.20 ? 267 LEU R CD1 1 
ATOM 7795 C CD2 . LEU E 5 320 ? 108.356 85.684  142.418 1.00 148.89 ? 267 LEU R CD2 1 
ATOM 7796 N N   . PRO E 5 321 ? 109.219 81.472  144.766 1.00 155.59 ? 268 PRO R N   1 
ATOM 7797 C CA  . PRO E 5 321 ? 109.742 80.383  145.610 1.00 155.13 ? 268 PRO R CA  1 
ATOM 7798 C C   . PRO E 5 321 ? 110.173 80.834  146.994 1.00 155.74 ? 268 PRO R C   1 
ATOM 7799 O O   . PRO E 5 321 ? 110.010 80.078  147.960 1.00 154.95 ? 268 PRO R O   1 
ATOM 7800 C CB  . PRO E 5 321 ? 110.927 79.847  144.793 1.00 154.91 ? 268 PRO R CB  1 
ATOM 7801 C CG  . PRO E 5 321 ? 111.310 80.973  143.888 1.00 155.04 ? 268 PRO R CG  1 
ATOM 7802 C CD  . PRO E 5 321 ? 110.029 81.671  143.553 1.00 154.23 ? 268 PRO R CD  1 
ATOM 7803 N N   . ASN E 5 322 ? 110.722 82.041  147.123 1.00 159.09 ? 269 ASN R N   1 
ATOM 7804 C CA  . ASN E 5 322 ? 111.149 82.593  148.408 1.00 157.97 ? 269 ASN R CA  1 
ATOM 7805 C C   . ASN E 5 322 ? 110.584 84.000  148.546 1.00 158.39 ? 269 ASN R C   1 
ATOM 7806 O O   . ASN E 5 322 ? 111.297 84.991  148.341 1.00 158.01 ? 269 ASN R O   1 
ATOM 7807 C CB  . ASN E 5 322 ? 112.673 82.593  148.532 1.00 157.19 ? 269 ASN R CB  1 
ATOM 7808 C CG  . ASN E 5 322 ? 113.269 81.206  148.391 1.00 158.05 ? 269 ASN R CG  1 
ATOM 7809 O OD1 . ASN E 5 322 ? 113.429 80.484  149.375 1.00 159.21 ? 269 ASN R OD1 1 
ATOM 7810 N ND2 . ASN E 5 322 ? 113.600 80.827  147.162 1.00 157.36 ? 269 ASN R ND2 1 
ATOM 7811 N N   . PRO E 5 323 ? 109.302 84.125  148.900 1.00 161.50 ? 270 PRO R N   1 
ATOM 7812 C CA  . PRO E 5 323 ? 108.679 85.459  148.948 1.00 161.49 ? 270 PRO R CA  1 
ATOM 7813 C C   . PRO E 5 323 ? 109.328 86.405  149.944 1.00 161.06 ? 270 PRO R C   1 
ATOM 7814 O O   . PRO E 5 323 ? 109.203 87.626  149.784 1.00 158.66 ? 270 PRO R O   1 
ATOM 7815 C CB  . PRO E 5 323 ? 107.225 85.153  149.332 1.00 160.90 ? 270 PRO R CB  1 
ATOM 7816 C CG  . PRO E 5 323 ? 107.288 83.831  150.025 1.00 159.26 ? 270 PRO R CG  1 
ATOM 7817 C CD  . PRO E 5 323 ? 108.378 83.064  149.335 1.00 160.12 ? 270 PRO R CD  1 
ATOM 7818 N N   . ASP E 5 324 ? 110.009 85.887  150.968 1.00 158.66 ? 271 ASP R N   1 
ATOM 7819 C CA  . ASP E 5 324 ? 110.709 86.758  151.907 1.00 157.43 ? 271 ASP R CA  1 
ATOM 7820 C C   . ASP E 5 324 ? 111.849 87.509  151.228 1.00 156.97 ? 271 ASP R C   1 
ATOM 7821 O O   . ASP E 5 324 ? 112.055 88.700  151.488 1.00 155.66 ? 271 ASP R O   1 
ATOM 7822 C CB  . ASP E 5 324 ? 111.232 85.942  153.088 1.00 157.60 ? 271 ASP R CB  1 
ATOM 7823 C CG  . ASP E 5 324 ? 110.123 85.253  153.857 1.00 156.78 ? 271 ASP R CG  1 
ATOM 7824 O OD1 . ASP E 5 324 ? 108.995 85.789  153.886 1.00 157.24 ? 271 ASP R OD1 1 
ATOM 7825 O OD2 . ASP E 5 324 ? 110.378 84.175  154.435 1.00 156.44 ? 271 ASP R OD2 1 
ATOM 7826 N N   . THR E 5 325 ? 112.599 86.834  150.356 1.00 159.28 ? 272 THR R N   1 
ATOM 7827 C CA  . THR E 5 325 ? 113.772 87.423  149.723 1.00 159.50 ? 272 THR R CA  1 
ATOM 7828 C C   . THR E 5 325 ? 113.598 87.708  148.240 1.00 158.45 ? 272 THR R C   1 
ATOM 7829 O O   . THR E 5 325 ? 114.204 88.655  147.734 1.00 156.91 ? 272 THR R O   1 
ATOM 7830 C CB  . THR E 5 325 ? 114.992 86.510  149.906 1.00 158.39 ? 272 THR R CB  1 
ATOM 7831 O OG1 . THR E 5 325 ? 114.732 85.236  149.304 1.00 157.08 ? 272 THR R OG1 1 
ATOM 7832 C CG2 . THR E 5 325 ? 115.295 86.315  151.384 1.00 157.14 ? 272 THR R CG2 1 
ATOM 7833 N N   . ASP E 5 326 ? 112.792 86.918  147.530 1.00 153.43 ? 273 ASP R N   1 
ATOM 7834 C CA  . ASP E 5 326 ? 112.616 87.103  146.095 1.00 152.39 ? 273 ASP R CA  1 
ATOM 7835 C C   . ASP E 5 326 ? 111.628 88.211  145.755 1.00 152.48 ? 273 ASP R C   1 
ATOM 7836 O O   . ASP E 5 326 ? 111.469 88.535  144.573 1.00 152.64 ? 273 ASP R O   1 
ATOM 7837 C CB  . ASP E 5 326 ? 112.164 85.794  145.443 1.00 152.36 ? 273 ASP R CB  1 
ATOM 7838 C CG  . ASP E 5 326 ? 113.165 84.671  145.637 1.00 152.37 ? 273 ASP R CG  1 
ATOM 7839 O OD1 . ASP E 5 326 ? 114.205 84.906  146.286 1.00 152.71 ? 273 ASP R OD1 1 
ATOM 7840 O OD2 . ASP E 5 326 ? 112.912 83.554  145.140 1.00 152.77 ? 273 ASP R OD2 1 
ATOM 7841 N N   . LEU E 5 327 ? 110.963 88.793  146.754 1.00 140.65 ? 274 LEU R N   1 
ATOM 7842 C CA  . LEU E 5 327 ? 110.045 89.899  146.509 1.00 139.63 ? 274 LEU R CA  1 
ATOM 7843 C C   . LEU E 5 327 ? 110.765 91.153  146.028 1.00 137.94 ? 274 LEU R C   1 
ATOM 7844 O O   . LEU E 5 327 ? 110.146 91.993  145.367 1.00 135.16 ? 274 LEU R O   1 
ATOM 7845 C CB  . LEU E 5 327 ? 109.246 90.204  147.777 1.00 139.41 ? 274 LEU R CB  1 
ATOM 7846 C CG  . LEU E 5 327 ? 108.059 91.161  147.649 1.00 139.73 ? 274 LEU R CG  1 
ATOM 7847 C CD1 . LEU E 5 327 ? 107.057 90.641  146.630 1.00 138.91 ? 274 LEU R CD1 1 
ATOM 7848 C CD2 . LEU E 5 327 ? 107.393 91.377  149.000 1.00 139.45 ? 274 LEU R CD2 1 
ATOM 7849 N N   . TYR E 5 328 ? 112.056 91.294  146.335 1.00 140.10 ? 275 TYR R N   1 
ATOM 7850 C CA  . TYR E 5 328 ? 112.768 92.529  146.024 1.00 140.27 ? 275 TYR R CA  1 
ATOM 7851 C C   . TYR E 5 328 ? 113.147 92.605  144.549 1.00 140.04 ? 275 TYR R C   1 
ATOM 7852 O O   . TYR E 5 328 ? 112.843 93.596  143.876 1.00 140.28 ? 275 TYR R O   1 
ATOM 7853 C CB  . TYR E 5 328 ? 114.021 92.648  146.893 1.00 140.21 ? 275 TYR R CB  1 
ATOM 7854 C CG  . TYR E 5 328 ? 113.742 92.897  148.356 1.00 140.92 ? 275 TYR R CG  1 
ATOM 7855 C CD1 . TYR E 5 328 ? 113.615 94.190  148.848 1.00 140.47 ? 275 TYR R CD1 1 
ATOM 7856 C CD2 . TYR E 5 328 ? 113.615 91.841  149.248 1.00 140.33 ? 275 TYR R CD2 1 
ATOM 7857 C CE1 . TYR E 5 328 ? 113.363 94.423  150.186 1.00 140.95 ? 275 TYR R CE1 1 
ATOM 7858 C CE2 . TYR E 5 328 ? 113.363 92.064  150.588 1.00 141.11 ? 275 TYR R CE2 1 
ATOM 7859 C CZ  . TYR E 5 328 ? 113.238 93.357  151.051 1.00 141.70 ? 275 TYR R CZ  1 
ATOM 7860 O OH  . TYR E 5 328 ? 112.988 93.582  152.385 1.00 140.78 ? 275 TYR R OH  1 
ATOM 7861 N N   . TRP E 5 329 ? 113.812 91.569  144.030 1.00 133.79 ? 276 TRP R N   1 
ATOM 7862 C CA  . TRP E 5 329 ? 114.258 91.609  142.641 1.00 133.34 ? 276 TRP R CA  1 
ATOM 7863 C C   . TRP E 5 329 ? 113.089 91.636  141.666 1.00 132.15 ? 276 TRP R C   1 
ATOM 7864 O O   . TRP E 5 329 ? 113.223 92.171  140.561 1.00 131.53 ? 276 TRP R O   1 
ATOM 7865 C CB  . TRP E 5 329 ? 115.164 90.415  142.336 1.00 132.54 ? 276 TRP R CB  1 
ATOM 7866 C CG  . TRP E 5 329 ? 114.434 89.110  142.219 1.00 132.62 ? 276 TRP R CG  1 
ATOM 7867 C CD1 . TRP E 5 329 ? 114.215 88.201  143.211 1.00 133.39 ? 276 TRP R CD1 1 
ATOM 7868 C CD2 . TRP E 5 329 ? 113.830 88.566  141.037 1.00 132.07 ? 276 TRP R CD2 1 
ATOM 7869 N NE1 . TRP E 5 329 ? 113.510 87.127  142.724 1.00 134.15 ? 276 TRP R NE1 1 
ATOM 7870 C CE2 . TRP E 5 329 ? 113.261 87.327  141.391 1.00 134.23 ? 276 TRP R CE2 1 
ATOM 7871 C CE3 . TRP E 5 329 ? 113.714 89.008  139.715 1.00 130.14 ? 276 TRP R CE3 1 
ATOM 7872 C CZ2 . TRP E 5 329 ? 112.587 86.525  140.473 1.00 133.19 ? 276 TRP R CZ2 1 
ATOM 7873 C CZ3 . TRP E 5 329 ? 113.044 88.211  138.805 1.00 130.47 ? 276 TRP R CZ3 1 
ATOM 7874 C CH2 . TRP E 5 329 ? 112.489 86.983  139.188 1.00 131.59 ? 276 TRP R CH2 1 
ATOM 7875 N N   . PHE E 5 330 ? 111.942 91.068  142.044 1.00 127.19 ? 277 PHE R N   1 
ATOM 7876 C CA  . PHE E 5 330 ? 110.791 91.102  141.149 1.00 127.60 ? 277 PHE R CA  1 
ATOM 7877 C C   . PHE E 5 330 ? 110.268 92.523  140.976 1.00 126.26 ? 277 PHE R C   1 
ATOM 7878 O O   . PHE E 5 330 ? 109.938 92.937  139.859 1.00 126.52 ? 277 PHE R O   1 
ATOM 7879 C CB  . PHE E 5 330 ? 109.690 90.181  141.676 1.00 128.40 ? 277 PHE R CB  1 
ATOM 7880 C CG  . PHE E 5 330 ? 108.492 90.084  140.773 1.00 128.50 ? 277 PHE R CG  1 
ATOM 7881 C CD1 . PHE E 5 330 ? 108.501 89.234  139.680 1.00 127.99 ? 277 PHE R CD1 1 
ATOM 7882 C CD2 . PHE E 5 330 ? 107.355 90.834  141.023 1.00 126.55 ? 277 PHE R CD2 1 
ATOM 7883 C CE1 . PHE E 5 330 ? 107.400 89.139  138.848 1.00 126.20 ? 277 PHE R CE1 1 
ATOM 7884 C CE2 . PHE E 5 330 ? 106.252 90.744  140.195 1.00 125.19 ? 277 PHE R CE2 1 
ATOM 7885 C CZ  . PHE E 5 330 ? 106.275 89.895  139.107 1.00 125.50 ? 277 PHE R CZ  1 
ATOM 7886 N N   . THR E 5 331 ? 110.182 93.282  142.070 1.00 118.99 ? 278 THR R N   1 
ATOM 7887 C CA  . THR E 5 331 ? 109.697 94.656  141.978 1.00 119.24 ? 278 THR R CA  1 
ATOM 7888 C C   . THR E 5 331 ? 110.750 95.584  141.381 1.00 118.62 ? 278 THR R C   1 
ATOM 7889 O O   . THR E 5 331 ? 110.434 96.427  140.533 1.00 119.49 ? 278 THR R O   1 
ATOM 7890 C CB  . THR E 5 331 ? 109.265 95.149  143.359 1.00 123.02 ? 278 THR R CB  1 
ATOM 7891 O OG1 . THR E 5 331 ? 108.234 94.295  143.871 1.00 123.50 ? 278 THR R OG1 1 
ATOM 7892 C CG2 . THR E 5 331 ? 108.734 96.568  143.275 1.00 122.41 ? 278 THR R CG2 1 
ATOM 7893 N N   . LEU E 5 332 ? 112.008 95.442  141.810 1.00 115.75 ? 279 LEU R N   1 
ATOM 7894 C CA  . LEU E 5 332 ? 113.056 96.361  141.371 1.00 117.52 ? 279 LEU R CA  1 
ATOM 7895 C C   . LEU E 5 332 ? 113.366 96.202  139.887 1.00 119.07 ? 279 LEU R C   1 
ATOM 7896 O O   . LEU E 5 332 ? 113.557 97.198  139.178 1.00 119.38 ? 279 LEU R O   1 
ATOM 7897 C CB  . LEU E 5 332 ? 114.320 96.149  142.205 1.00 118.16 ? 279 LEU R CB  1 
ATOM 7898 C CG  . LEU E 5 332 ? 114.239 96.523  143.686 1.00 117.14 ? 279 LEU R CG  1 
ATOM 7899 C CD1 . LEU E 5 332 ? 115.552 96.213  144.386 1.00 117.96 ? 279 LEU R CD1 1 
ATOM 7900 C CD2 . LEU E 5 332 ? 113.879 97.991  143.845 1.00 115.79 ? 279 LEU R CD2 1 
ATOM 7901 N N   . TYR E 5 333 ? 113.426 94.961  139.400 1.00 108.07 ? 280 TYR R N   1 
ATOM 7902 C CA  . TYR E 5 333 ? 113.762 94.730  137.999 1.00 104.78 ? 280 TYR R CA  1 
ATOM 7903 C C   . TYR E 5 333 ? 112.660 95.214  137.065 1.00 102.75 ? 280 TYR R C   1 
ATOM 7904 O O   . TYR E 5 333 ? 112.947 95.632  135.937 1.00 102.72 ? 280 TYR R O   1 
ATOM 7905 C CB  . TYR E 5 333 ? 114.067 93.247  137.773 1.00 105.59 ? 280 TYR R CB  1 
ATOM 7906 C CG  . TYR E 5 333 ? 113.150 92.543  136.799 1.00 104.03 ? 280 TYR R CG  1 
ATOM 7907 C CD1 . TYR E 5 333 ? 111.980 91.937  137.234 1.00 105.33 ? 280 TYR R CD1 1 
ATOM 7908 C CD2 . TYR E 5 333 ? 113.465 92.463  135.449 1.00 102.43 ? 280 TYR R CD2 1 
ATOM 7909 C CE1 . TYR E 5 333 ? 111.142 91.286  136.351 1.00 105.32 ? 280 TYR R CE1 1 
ATOM 7910 C CE2 . TYR E 5 333 ? 112.632 91.814  134.559 1.00 101.50 ? 280 TYR R CE2 1 
ATOM 7911 C CZ  . TYR E 5 333 ? 111.473 91.227  135.016 1.00 103.90 ? 280 TYR R CZ  1 
ATOM 7912 O OH  . TYR E 5 333 ? 110.640 90.578  134.135 1.00 109.92 ? 280 TYR R OH  1 
ATOM 7913 N N   . GLN E 5 334 ? 111.403 95.169  137.510 1.00 106.38 ? 281 GLN R N   1 
ATOM 7914 C CA  . GLN E 5 334 ? 110.320 95.717  136.700 1.00 105.43 ? 281 GLN R CA  1 
ATOM 7915 C C   . GLN E 5 334 ? 110.337 97.240  136.709 1.00 104.84 ? 281 GLN R C   1 
ATOM 7916 O O   . GLN E 5 334 ? 110.036 97.873  135.691 1.00 106.35 ? 281 GLN R O   1 
ATOM 7917 C CB  . GLN E 5 334 ? 108.973 95.198  137.203 1.00 104.41 ? 281 GLN R CB  1 
ATOM 7918 C CG  . GLN E 5 334 ? 108.712 93.737  136.893 1.00 107.54 ? 281 GLN R CG  1 
ATOM 7919 C CD  . GLN E 5 334 ? 107.324 93.295  137.308 1.00 111.15 ? 281 GLN R CD  1 
ATOM 7920 O OE1 . GLN E 5 334 ? 106.886 92.193  136.977 1.00 112.67 ? 281 GLN R OE1 1 
ATOM 7921 N NE2 . GLN E 5 334 ? 106.623 94.153  138.039 1.00 108.68 ? 281 GLN R NE2 1 
ATOM 7922 N N   . PHE E 5 335 ? 110.679 97.847  137.847 1.00 99.79  ? 282 PHE R N   1 
ATOM 7923 C CA  . PHE E 5 335 ? 110.785 99.302  137.899 1.00 100.56 ? 282 PHE R CA  1 
ATOM 7924 C C   . PHE E 5 335 ? 111.891 99.811  136.984 1.00 102.82 ? 282 PHE R C   1 
ATOM 7925 O O   . PHE E 5 335 ? 111.718 100.822 136.292 1.00 106.40 ? 282 PHE R O   1 
ATOM 7926 C CB  . PHE E 5 335 ? 111.024 99.754  139.340 1.00 99.39  ? 282 PHE R CB  1 
ATOM 7927 C CG  . PHE E 5 335 ? 111.378 101.210 139.474 1.00 100.67 ? 282 PHE R CG  1 
ATOM 7928 C CD1 . PHE E 5 335 ? 110.390 102.181 139.471 1.00 100.75 ? 282 PHE R CD1 1 
ATOM 7929 C CD2 . PHE E 5 335 ? 112.698 101.606 139.621 1.00 100.84 ? 282 PHE R CD2 1 
ATOM 7930 C CE1 . PHE E 5 335 ? 110.712 103.519 139.601 1.00 102.18 ? 282 PHE R CE1 1 
ATOM 7931 C CE2 . PHE E 5 335 ? 113.026 102.942 139.750 1.00 102.59 ? 282 PHE R CE2 1 
ATOM 7932 C CZ  . PHE E 5 335 ? 112.031 103.900 139.740 1.00 103.52 ? 282 PHE R CZ  1 
ATOM 7933 N N   . PHE E 5 336 ? 113.039 99.131  136.972 1.00 94.57  ? 283 PHE R N   1 
ATOM 7934 C CA  . PHE E 5 336 ? 114.153 99.587  136.147 1.00 97.20  ? 283 PHE R CA  1 
ATOM 7935 C C   . PHE E 5 336 ? 113.879 99.370  134.663 1.00 96.18  ? 283 PHE R C   1 
ATOM 7936 O O   . PHE E 5 336 ? 114.035 100.291 133.853 1.00 93.95  ? 283 PHE R O   1 
ATOM 7937 C CB  . PHE E 5 336 ? 115.438 98.873  136.568 1.00 96.79  ? 283 PHE R CB  1 
ATOM 7938 C CG  . PHE E 5 336 ? 116.627 99.205  135.711 1.00 100.01 ? 283 PHE R CG  1 
ATOM 7939 C CD1 . PHE E 5 336 ? 117.323 100.389 135.893 1.00 97.83  ? 283 PHE R CD1 1 
ATOM 7940 C CD2 . PHE E 5 336 ? 117.053 98.329  134.725 1.00 97.37  ? 283 PHE R CD2 1 
ATOM 7941 C CE1 . PHE E 5 336 ? 118.418 100.694 135.106 1.00 96.03  ? 283 PHE R CE1 1 
ATOM 7942 C CE2 . PHE E 5 336 ? 118.146 98.629  133.935 1.00 95.14  ? 283 PHE R CE2 1 
ATOM 7943 C CZ  . PHE E 5 336 ? 118.829 99.812  134.126 1.00 95.51  ? 283 PHE R CZ  1 
ATOM 7944 N N   . LEU E 5 337 ? 113.461 98.159  134.286 1.00 86.42  ? 284 LEU R N   1 
ATOM 7945 C CA  . LEU E 5 337 ? 113.334 97.832  132.869 1.00 82.23  ? 284 LEU R CA  1 
ATOM 7946 C C   . LEU E 5 337 ? 112.082 98.418  132.230 1.00 82.94  ? 284 LEU R C   1 
ATOM 7947 O O   . LEU E 5 337 ? 112.096 98.727  131.033 1.00 85.92  ? 284 LEU R O   1 
ATOM 7948 C CB  . LEU E 5 337 ? 113.355 96.316  132.672 1.00 82.47  ? 284 LEU R CB  1 
ATOM 7949 C CG  . LEU E 5 337 ? 114.705 95.627  132.884 1.00 83.24  ? 284 LEU R CG  1 
ATOM 7950 C CD1 . LEU E 5 337 ? 114.606 94.144  132.571 1.00 87.18  ? 284 LEU R CD1 1 
ATOM 7951 C CD2 . LEU E 5 337 ? 115.781 96.285  132.035 1.00 80.63  ? 284 LEU R CD2 1 
ATOM 7952 N N   . ALA E 5 338 ? 110.998 98.579  132.990 1.00 76.36  ? 285 ALA R N   1 
ATOM 7953 C CA  . ALA E 5 338 ? 109.724 98.972  132.406 1.00 74.31  ? 285 ALA R CA  1 
ATOM 7954 C C   . ALA E 5 338 ? 109.312 100.404 132.708 1.00 79.58  ? 285 ALA R C   1 
ATOM 7955 O O   . ALA E 5 338 ? 108.465 100.944 131.990 1.00 79.28  ? 285 ALA R O   1 
ATOM 7956 C CB  . ALA E 5 338 ? 108.605 98.030  132.876 1.00 75.86  ? 285 ALA R CB  1 
ATOM 7957 N N   . PHE E 5 339 ? 109.870 101.028 133.743 1.00 86.85  ? 286 PHE R N   1 
ATOM 7958 C CA  . PHE E 5 339 ? 109.564 102.421 134.046 1.00 83.46  ? 286 PHE R CA  1 
ATOM 7959 C C   . PHE E 5 339 ? 110.785 103.324 134.008 1.00 83.61  ? 286 PHE R C   1 
ATOM 7960 O O   . PHE E 5 339 ? 110.777 104.333 133.296 1.00 84.74  ? 286 PHE R O   1 
ATOM 7961 C CB  . PHE E 5 339 ? 108.878 102.538 135.415 1.00 84.94  ? 286 PHE R CB  1 
ATOM 7962 C CG  . PHE E 5 339 ? 108.528 103.950 135.789 1.00 84.70  ? 286 PHE R CG  1 
ATOM 7963 C CD1 . PHE E 5 339 ? 107.459 104.592 135.187 1.00 84.15  ? 286 PHE R CD1 1 
ATOM 7964 C CD2 . PHE E 5 339 ? 109.272 104.639 136.731 1.00 85.31  ? 286 PHE R CD2 1 
ATOM 7965 C CE1 . PHE E 5 339 ? 107.134 105.892 135.523 1.00 86.05  ? 286 PHE R CE1 1 
ATOM 7966 C CE2 . PHE E 5 339 ? 108.951 105.940 137.072 1.00 89.84  ? 286 PHE R CE2 1 
ATOM 7967 C CZ  . PHE E 5 339 ? 107.881 106.567 136.466 1.00 90.23  ? 286 PHE R CZ  1 
ATOM 7968 N N   . ALA E 5 340 ? 111.841 102.989 134.751 1.00 83.26  ? 287 ALA R N   1 
ATOM 7969 C CA  . ALA E 5 340 ? 112.936 103.934 134.952 1.00 83.15  ? 287 ALA R CA  1 
ATOM 7970 C C   . ALA E 5 340 ? 113.757 104.109 133.681 1.00 86.56  ? 287 ALA R C   1 
ATOM 7971 O O   . ALA E 5 340 ? 113.882 105.222 133.157 1.00 89.03  ? 287 ALA R O   1 
ATOM 7972 C CB  . ALA E 5 340 ? 113.822 103.470 136.109 1.00 82.74  ? 287 ALA R CB  1 
ATOM 7973 N N   . LEU E 5 341 ? 114.331 103.019 133.172 1.00 77.89  ? 288 LEU R N   1 
ATOM 7974 C CA  . LEU E 5 341 ? 115.173 103.116 131.981 1.00 79.23  ? 288 LEU R CA  1 
ATOM 7975 C C   . LEU E 5 341 ? 114.428 103.671 130.772 1.00 78.27  ? 288 LEU R C   1 
ATOM 7976 O O   . LEU E 5 341 ? 114.969 104.572 130.108 1.00 81.24  ? 288 LEU R O   1 
ATOM 7977 C CB  . LEU E 5 341 ? 115.796 101.750 131.675 1.00 78.33  ? 288 LEU R CB  1 
ATOM 7978 C CG  . LEU E 5 341 ? 116.711 101.680 130.451 1.00 77.06  ? 288 LEU R CG  1 
ATOM 7979 C CD1 . LEU E 5 341 ? 117.897 102.618 130.613 1.00 79.44  ? 288 LEU R CD1 1 
ATOM 7980 C CD2 . LEU E 5 341 ? 117.179 100.254 130.212 1.00 77.12  ? 288 LEU R CD2 1 
ATOM 7981 N N   . PRO E 5 342 ? 113.225 103.196 130.416 1.00 68.89  ? 289 PRO R N   1 
ATOM 7982 C CA  . PRO E 5 342 ? 112.525 103.820 129.279 1.00 69.06  ? 289 PRO R CA  1 
ATOM 7983 C C   . PRO E 5 342 ? 112.217 105.292 129.487 1.00 76.05  ? 289 PRO R C   1 
ATOM 7984 O O   . PRO E 5 342 ? 112.299 106.072 128.531 1.00 82.10  ? 289 PRO R O   1 
ATOM 7985 C CB  . PRO E 5 342 ? 111.245 102.982 129.158 1.00 59.71  ? 289 PRO R CB  1 
ATOM 7986 C CG  . PRO E 5 342 ? 111.055 102.389 130.502 1.00 69.70  ? 289 PRO R CG  1 
ATOM 7987 C CD  . PRO E 5 342 ? 112.435 102.090 130.985 1.00 72.29  ? 289 PRO R CD  1 
ATOM 7988 N N   . PHE E 5 343 ? 111.864 105.701 130.709 1.00 73.34  ? 290 PHE R N   1 
ATOM 7989 C CA  . PHE E 5 343 ? 111.539 107.106 130.937 1.00 70.66  ? 290 PHE R CA  1 
ATOM 7990 C C   . PHE E 5 343 ? 112.773 107.987 130.809 1.00 67.47  ? 290 PHE R C   1 
ATOM 7991 O O   . PHE E 5 343 ? 112.684 109.123 130.331 1.00 73.49  ? 290 PHE R O   1 
ATOM 7992 C CB  . PHE E 5 343 ? 110.892 107.296 132.306 1.00 73.66  ? 290 PHE R CB  1 
ATOM 7993 C CG  . PHE E 5 343 ? 110.508 108.718 132.595 1.00 72.34  ? 290 PHE R CG  1 
ATOM 7994 C CD1 . PHE E 5 343 ? 109.417 109.294 131.968 1.00 72.24  ? 290 PHE R CD1 1 
ATOM 7995 C CD2 . PHE E 5 343 ? 111.238 109.481 133.491 1.00 73.94  ? 290 PHE R CD2 1 
ATOM 7996 C CE1 . PHE E 5 343 ? 109.061 110.602 132.226 1.00 76.88  ? 290 PHE R CE1 1 
ATOM 7997 C CE2 . PHE E 5 343 ? 110.885 110.790 133.756 1.00 75.61  ? 290 PHE R CE2 1 
ATOM 7998 C CZ  . PHE E 5 343 ? 109.795 111.351 133.123 1.00 78.26  ? 290 PHE R CZ  1 
ATOM 7999 N N   . VAL E 5 344 ? 113.932 107.483 131.238 1.00 58.85  ? 291 VAL R N   1 
ATOM 8000 C CA  . VAL E 5 344 ? 115.173 108.234 131.070 1.00 63.76  ? 291 VAL R CA  1 
ATOM 8001 C C   . VAL E 5 344 ? 115.470 108.430 129.589 1.00 65.01  ? 291 VAL R C   1 
ATOM 8002 O O   . VAL E 5 344 ? 115.815 109.531 129.147 1.00 67.57  ? 291 VAL R O   1 
ATOM 8003 C CB  . VAL E 5 344 ? 116.333 107.527 131.794 1.00 63.20  ? 291 VAL R CB  1 
ATOM 8004 C CG1 . VAL E 5 344 ? 117.654 108.193 131.452 1.00 66.39  ? 291 VAL R CG1 1 
ATOM 8005 C CG2 . VAL E 5 344 ? 116.108 107.544 133.296 1.00 61.28  ? 291 VAL R CG2 1 
ATOM 8006 N N   . VAL E 5 345 ? 115.325 107.365 128.797 1.00 57.80  ? 292 VAL R N   1 
ATOM 8007 C CA  . VAL E 5 345 ? 115.625 107.458 127.372 1.00 54.77  ? 292 VAL R CA  1 
ATOM 8008 C C   . VAL E 5 345 ? 114.598 108.333 126.663 1.00 51.21  ? 292 VAL R C   1 
ATOM 8009 O O   . VAL E 5 345 ? 114.951 109.161 125.815 1.00 61.12  ? 292 VAL R O   1 
ATOM 8010 C CB  . VAL E 5 345 ? 115.702 106.053 126.746 1.00 55.13  ? 292 VAL R CB  1 
ATOM 8011 C CG1 . VAL E 5 345 ? 115.976 106.153 125.254 1.00 54.91  ? 292 VAL R CG1 1 
ATOM 8012 C CG2 . VAL E 5 345 ? 116.780 105.228 127.430 1.00 60.67  ? 292 VAL R CG2 1 
ATOM 8013 N N   . ILE E 5 346 ? 113.315 108.165 126.994 1.00 48.01  ? 293 ILE R N   1 
ATOM 8014 C CA  . ILE E 5 346 ? 112.277 108.976 126.360 1.00 55.68  ? 293 ILE R CA  1 
ATOM 8015 C C   . ILE E 5 346 ? 112.463 110.447 126.708 1.00 64.04  ? 293 ILE R C   1 
ATOM 8016 O O   . ILE E 5 346 ? 112.363 111.322 125.839 1.00 72.83  ? 293 ILE R O   1 
ATOM 8017 C CB  . ILE E 5 346 ? 110.878 108.470 126.760 1.00 50.04  ? 293 ILE R CB  1 
ATOM 8018 C CG1 . ILE E 5 346 ? 110.584 107.127 126.091 1.00 53.92  ? 293 ILE R CG1 1 
ATOM 8019 C CG2 . ILE E 5 346 ? 109.812 109.487 126.386 1.00 52.13  ? 293 ILE R CG2 1 
ATOM 8020 C CD1 . ILE E 5 346 ? 109.237 106.545 126.457 1.00 65.00  ? 293 ILE R CD1 1 
ATOM 8021 N N   . THR E 5 347 ? 112.747 110.746 127.978 1.00 60.19  ? 294 THR R N   1 
ATOM 8022 C CA  . THR E 5 347 ? 112.979 112.134 128.365 1.00 58.47  ? 294 THR R CA  1 
ATOM 8023 C C   . THR E 5 347 ? 114.259 112.678 127.744 1.00 59.07  ? 294 THR R C   1 
ATOM 8024 O O   . THR E 5 347 ? 114.282 113.813 127.255 1.00 65.76  ? 294 THR R O   1 
ATOM 8025 C CB  . THR E 5 347 ? 113.034 112.257 129.888 1.00 67.93  ? 294 THR R CB  1 
ATOM 8026 O OG1 . THR E 5 347 ? 111.835 111.717 130.458 1.00 72.41  ? 294 THR R OG1 1 
ATOM 8027 C CG2 . THR E 5 347 ? 113.173 113.714 130.302 1.00 64.97  ? 294 THR R CG2 1 
ATOM 8028 N N   . ALA E 5 348 ? 115.333 111.881 127.746 1.00 59.74  ? 295 ALA R N   1 
ATOM 8029 C CA  . ALA E 5 348 ? 116.598 112.346 127.186 1.00 66.98  ? 295 ALA R CA  1 
ATOM 8030 C C   . ALA E 5 348 ? 116.480 112.599 125.690 1.00 71.82  ? 295 ALA R C   1 
ATOM 8031 O O   . ALA E 5 348 ? 117.055 113.560 125.168 1.00 71.38  ? 295 ALA R O   1 
ATOM 8032 C CB  . ALA E 5 348 ? 117.710 111.336 127.470 1.00 65.94  ? 295 ALA R CB  1 
ATOM 8033 N N   . ALA E 5 349 ? 115.746 111.741 124.980 1.00 69.74  ? 296 ALA R N   1 
ATOM 8034 C CA  . ALA E 5 349 ? 115.614 111.910 123.538 1.00 61.03  ? 296 ALA R CA  1 
ATOM 8035 C C   . ALA E 5 349 ? 114.845 113.180 123.196 1.00 67.73  ? 296 ALA R C   1 
ATOM 8036 O O   . ALA E 5 349 ? 115.239 113.924 122.290 1.00 84.63  ? 296 ALA R O   1 
ATOM 8037 C CB  . ALA E 5 349 ? 114.932 110.687 122.926 1.00 57.51  ? 296 ALA R CB  1 
ATOM 8038 N N   . TYR E 5 350 ? 113.746 113.447 123.905 1.00 47.07  ? 297 TYR R N   1 
ATOM 8039 C CA  . TYR E 5 350 ? 112.895 114.573 123.533 1.00 52.69  ? 297 TYR R CA  1 
ATOM 8040 C C   . TYR E 5 350 ? 113.516 115.912 123.918 1.00 63.68  ? 297 TYR R C   1 
ATOM 8041 O O   . TYR E 5 350 ? 113.293 116.912 123.227 1.00 66.17  ? 297 TYR R O   1 
ATOM 8042 C CB  . TYR E 5 350 ? 111.514 114.414 124.164 1.00 49.52  ? 297 TYR R CB  1 
ATOM 8043 C CG  . TYR E 5 350 ? 110.595 113.516 123.366 1.00 53.53  ? 297 TYR R CG  1 
ATOM 8044 C CD1 . TYR E 5 350 ? 110.030 113.950 122.176 1.00 48.54  ? 297 TYR R CD1 1 
ATOM 8045 C CD2 . TYR E 5 350 ? 110.294 112.233 123.802 1.00 65.62  ? 297 TYR R CD2 1 
ATOM 8046 C CE1 . TYR E 5 350 ? 109.194 113.131 121.442 1.00 57.25  ? 297 TYR R CE1 1 
ATOM 8047 C CE2 . TYR E 5 350 ? 109.458 111.408 123.076 1.00 64.36  ? 297 TYR R CE2 1 
ATOM 8048 C CZ  . TYR E 5 350 ? 108.911 111.862 121.897 1.00 65.19  ? 297 TYR R CZ  1 
ATOM 8049 O OH  . TYR E 5 350 ? 108.079 111.043 121.167 1.00 60.78  ? 297 TYR R OH  1 
ATOM 8050 N N   . VAL E 5 351 ? 114.291 115.959 125.005 1.00 67.61  ? 298 VAL R N   1 
ATOM 8051 C CA  . VAL E 5 351 ? 114.967 117.205 125.359 1.00 66.38  ? 298 VAL R CA  1 
ATOM 8052 C C   . VAL E 5 351 ? 116.090 117.497 124.371 1.00 67.16  ? 298 VAL R C   1 
ATOM 8053 O O   . VAL E 5 351 ? 116.361 118.662 124.054 1.00 65.53  ? 298 VAL R O   1 
ATOM 8054 C CB  . VAL E 5 351 ? 115.474 117.178 126.816 1.00 59.67  ? 298 VAL R CB  1 
ATOM 8055 C CG1 . VAL E 5 351 ? 114.306 117.021 127.782 1.00 57.46  ? 298 VAL R CG1 1 
ATOM 8056 C CG2 . VAL E 5 351 ? 116.506 116.082 127.025 1.00 60.57  ? 298 VAL R CG2 1 
ATOM 8057 N N   . ARG E 5 352 ? 116.763 116.457 123.871 1.00 69.43  ? 299 ARG R N   1 
ATOM 8058 C CA  . ARG E 5 352 ? 117.785 116.659 122.852 1.00 69.81  ? 299 ARG R CA  1 
ATOM 8059 C C   . ARG E 5 352 ? 117.176 117.109 121.532 1.00 64.69  ? 299 ARG R C   1 
ATOM 8060 O O   . ARG E 5 352 ? 117.827 117.828 120.765 1.00 72.21  ? 299 ARG R O   1 
ATOM 8061 C CB  . ARG E 5 352 ? 118.590 115.375 122.648 1.00 71.41  ? 299 ARG R CB  1 
ATOM 8062 C CG  . ARG E 5 352 ? 119.488 114.997 123.812 1.00 73.46  ? 299 ARG R CG  1 
ATOM 8063 C CD  . ARG E 5 352 ? 120.722 115.883 123.868 1.00 76.22  ? 299 ARG R CD  1 
ATOM 8064 N NE  . ARG E 5 352 ? 121.692 115.521 122.840 1.00 79.04  ? 299 ARG R NE  1 
ATOM 8065 C CZ  . ARG E 5 352 ? 121.798 116.120 121.662 1.00 76.21  ? 299 ARG R CZ  1 
ATOM 8066 N NH1 . ARG E 5 352 ? 121.003 117.122 121.322 1.00 77.21  ? 299 ARG R NH1 1 
ATOM 8067 N NH2 . ARG E 5 352 ? 122.719 115.699 120.800 1.00 74.12  ? 299 ARG R NH2 1 
ATOM 8068 N N   . ILE E 5 353 ? 115.941 116.692 121.243 1.00 48.62  ? 300 ILE R N   1 
ATOM 8069 C CA  . ILE E 5 353 ? 115.261 117.181 120.048 1.00 54.37  ? 300 ILE R CA  1 
ATOM 8070 C C   . ILE E 5 353 ? 115.010 118.679 120.152 1.00 70.20  ? 300 ILE R C   1 
ATOM 8071 O O   . ILE E 5 353 ? 115.263 119.431 119.204 1.00 78.78  ? 300 ILE R O   1 
ATOM 8072 C CB  . ILE E 5 353 ? 113.951 116.403 119.818 1.00 47.37  ? 300 ILE R CB  1 
ATOM 8073 C CG1 . ILE E 5 353 ? 114.251 114.962 119.403 1.00 57.25  ? 300 ILE R CG1 1 
ATOM 8074 C CG2 . ILE E 5 353 ? 113.090 117.096 118.770 1.00 50.28  ? 300 ILE R CG2 1 
ATOM 8075 C CD1 . ILE E 5 353 ? 113.015 114.125 119.164 1.00 62.41  ? 300 ILE R CD1 1 
ATOM 8076 N N   . LEU E 5 354 ? 114.537 119.142 121.312 1.00 64.43  ? 301 LEU R N   1 
ATOM 8077 C CA  . LEU E 5 354 ? 114.247 120.564 121.471 1.00 63.05  ? 301 LEU R CA  1 
ATOM 8078 C C   . LEU E 5 354 ? 115.507 121.419 121.405 1.00 66.58  ? 301 LEU R C   1 
ATOM 8079 O O   . LEU E 5 354 ? 115.441 122.579 120.984 1.00 67.48  ? 301 LEU R O   1 
ATOM 8080 C CB  . LEU E 5 354 ? 113.511 120.809 122.788 1.00 61.29  ? 301 LEU R CB  1 
ATOM 8081 C CG  . LEU E 5 354 ? 112.240 119.991 123.022 1.00 59.62  ? 301 LEU R CG  1 
ATOM 8082 C CD1 . LEU E 5 354 ? 111.570 120.399 124.324 1.00 63.08  ? 301 LEU R CD1 1 
ATOM 8083 C CD2 . LEU E 5 354 ? 111.286 120.140 121.850 1.00 61.78  ? 301 LEU R CD2 1 
ATOM 8084 N N   . GLN E 5 355 ? 116.653 120.874 121.811 1.00 70.65  ? 302 GLN R N   1 
ATOM 8085 C CA  . GLN E 5 355 ? 117.898 121.631 121.775 1.00 72.73  ? 302 GLN R CA  1 
ATOM 8086 C C   . GLN E 5 355 ? 118.567 121.623 120.407 1.00 72.83  ? 302 GLN R C   1 
ATOM 8087 O O   . GLN E 5 355 ? 119.462 122.442 120.173 1.00 77.41  ? 302 GLN R O   1 
ATOM 8088 C CB  . GLN E 5 355 ? 118.870 121.087 122.825 1.00 73.91  ? 302 GLN R CB  1 
ATOM 8089 C CG  . GLN E 5 355 ? 118.380 121.247 124.254 1.00 79.05  ? 302 GLN R CG  1 
ATOM 8090 C CD  . GLN E 5 355 ? 119.355 120.694 125.275 1.00 80.85  ? 302 GLN R CD  1 
ATOM 8091 O OE1 . GLN E 5 355 ? 120.366 120.087 124.922 1.00 79.44  ? 302 GLN R OE1 1 
ATOM 8092 N NE2 . GLN E 5 355 ? 119.054 120.903 126.552 1.00 77.39  ? 302 GLN R NE2 1 
ATOM 8093 N N   . ARG E 5 356 ? 118.164 120.726 119.502 1.00 72.17  ? 303 ARG R N   1 
ATOM 8094 C CA  . ARG E 5 356 ? 118.841 120.585 118.218 1.00 73.80  ? 303 ARG R CA  1 
ATOM 8095 C C   . ARG E 5 356 ? 117.849 120.410 117.074 1.00 73.84  ? 303 ARG R C   1 
ATOM 8096 O O   . ARG E 5 356 ? 118.153 119.737 116.083 1.00 75.32  ? 303 ARG R O   1 
ATOM 8097 C CB  . ARG E 5 356 ? 119.823 119.410 118.241 1.00 75.34  ? 303 ARG R CB  1 
ATOM 8098 C CG  . ARG E 5 356 ? 121.025 119.625 119.148 1.00 72.88  ? 303 ARG R CG  1 
ATOM 8099 C CD  . ARG E 5 356 ? 122.196 120.235 118.393 1.00 71.10  ? 303 ARG R CD  1 
ATOM 8100 N NE  . ARG E 5 356 ? 122.983 119.226 117.694 1.00 73.79  ? 303 ARG R NE  1 
ATOM 8101 C CZ  . ARG E 5 356 ? 122.815 118.891 116.422 1.00 74.87  ? 303 ARG R CZ  1 
ATOM 8102 N NH1 . ARG E 5 356 ? 121.897 119.475 115.668 1.00 71.00  ? 303 ARG R NH1 1 
ATOM 8103 N NH2 . ARG E 5 356 ? 123.588 117.948 115.891 1.00 75.24  ? 303 ARG R NH2 1 
ATOM 8104 N N   . MET E 5 357 ? 116.663 121.003 117.190 1.00 78.39  ? 304 MET R N   1 
ATOM 8105 C CA  . MET E 5 357 ? 115.633 120.878 116.168 1.00 82.39  ? 304 MET R CA  1 
ATOM 8106 C C   . MET E 5 357 ? 115.757 121.918 115.065 1.00 92.83  ? 304 MET R C   1 
ATOM 8107 O O   . MET E 5 357 ? 114.994 121.863 114.095 1.00 94.88  ? 304 MET R O   1 
ATOM 8108 C CB  . MET E 5 357 ? 114.243 120.962 116.804 1.00 79.70  ? 304 MET R CB  1 
ATOM 8109 C CG  . MET E 5 357 ? 113.897 122.311 117.394 1.00 84.04  ? 304 MET R CG  1 
ATOM 8110 S SD  . MET E 5 357 ? 112.190 122.339 117.963 1.00 98.05  ? 304 MET R SD  1 
ATOM 8111 C CE  . MET E 5 357 ? 111.333 122.530 116.407 1.00 88.17  ? 304 MET R CE  1 
ATOM 8112 N N   . THR E 5 358 ? 116.699 122.853 115.179 1.00 111.92 ? 305 THR R N   1 
ATOM 8113 C CA  . THR E 5 358 ? 116.871 123.906 114.190 1.00 109.71 ? 305 THR R CA  1 
ATOM 8114 C C   . THR E 5 358 ? 118.353 124.219 114.050 1.00 109.01 ? 305 THR R C   1 
ATOM 8115 O O   . THR E 5 358 ? 119.157 123.953 114.947 1.00 109.58 ? 305 THR R O   1 
ATOM 8116 C CB  . THR E 5 358 ? 116.119 125.198 114.564 1.00 108.34 ? 305 THR R CB  1 
ATOM 8117 O OG1 . THR E 5 358 ? 116.552 125.653 115.853 1.00 108.05 ? 305 THR R OG1 1 
ATOM 8118 C CG2 . THR E 5 358 ? 114.608 124.988 114.576 1.00 107.62 ? 305 THR R CG2 1 
ATOM 8119 N N   . SER E 5 359 ? 118.700 124.795 112.907 1.00 113.08 ? 306 SER R N   1 
ATOM 8120 C CA  . SER E 5 359 ? 120.080 124.936 112.474 1.00 114.75 ? 306 SER R CA  1 
ATOM 8121 C C   . SER E 5 359 ? 120.596 126.334 112.791 1.00 114.60 ? 306 SER R C   1 
ATOM 8122 O O   . SER E 5 359 ? 119.829 127.253 113.089 1.00 112.41 ? 306 SER R O   1 
ATOM 8123 C CB  . SER E 5 359 ? 120.211 124.653 110.975 1.00 111.82 ? 306 SER R CB  1 
ATOM 8124 O OG  . SER E 5 359 ? 121.546 124.831 110.536 1.00 113.88 ? 306 SER R OG  1 
ATOM 8125 N N   . SER E 5 360 ? 121.922 126.480 112.741 1.00 121.46 ? 307 SER R N   1 
ATOM 8126 C CA  . SER E 5 360 ? 122.528 127.776 113.025 1.00 121.01 ? 307 SER R CA  1 
ATOM 8127 C C   . SER E 5 360 ? 122.089 128.815 112.002 1.00 120.22 ? 307 SER R C   1 
ATOM 8128 O O   . SER E 5 360 ? 121.803 129.966 112.354 1.00 119.27 ? 307 SER R O   1 
ATOM 8129 C CB  . SER E 5 360 ? 124.052 127.651 113.046 1.00 121.98 ? 307 SER R CB  1 
ATOM 8130 O OG  . SER E 5 360 ? 124.544 127.194 111.798 1.00 121.30 ? 307 SER R OG  1 
ATOM 8131 N N   . VAL E 5 361 ? 122.028 128.425 110.725 1.00 109.22 ? 308 VAL R N   1 
ATOM 8132 C CA  . VAL E 5 361 ? 121.637 129.346 109.659 1.00 108.43 ? 308 VAL R CA  1 
ATOM 8133 C C   . VAL E 5 361 ? 120.136 129.599 109.646 1.00 108.16 ? 308 VAL R C   1 
ATOM 8134 O O   . VAL E 5 361 ? 119.677 130.547 108.994 1.00 104.12 ? 308 VAL R O   1 
ATOM 8135 C CB  . VAL E 5 361 ? 122.158 128.761 108.329 1.00 102.72 ? 308 VAL R CB  1 
ATOM 8136 C CG1 . VAL E 5 361 ? 121.715 129.580 107.128 1.00 103.11 ? 308 VAL R CG1 1 
ATOM 8137 C CG2 . VAL E 5 361 ? 123.676 128.640 108.363 1.00 103.52 ? 308 VAL R CG2 1 
ATOM 8138 N N   . ALA E 5 362 ? 119.366 128.822 110.400 1.00 113.32 ? 309 ALA R N   1 
ATOM 8139 C CA  . ALA E 5 362 ? 117.916 128.984 110.414 1.00 111.86 ? 309 ALA R CA  1 
ATOM 8140 C C   . ALA E 5 362 ? 117.545 130.339 111.008 1.00 114.71 ? 309 ALA R C   1 
ATOM 8141 O O   . ALA E 5 362 ? 118.099 130.730 112.042 1.00 115.10 ? 309 ALA R O   1 
ATOM 8142 C CB  . ALA E 5 362 ? 117.258 127.860 111.210 1.00 111.00 ? 309 ALA R CB  1 
ATOM 8143 N N   . PRO E 5 363 ? 116.621 131.079 110.394 1.00 107.88 ? 310 PRO R N   1 
ATOM 8144 C CA  . PRO E 5 363 ? 116.261 132.400 110.928 1.00 107.69 ? 310 PRO R CA  1 
ATOM 8145 C C   . PRO E 5 363 ? 115.405 132.305 112.181 1.00 109.09 ? 310 PRO R C   1 
ATOM 8146 O O   . PRO E 5 363 ? 114.173 132.359 112.110 1.00 111.33 ? 310 PRO R O   1 
ATOM 8147 C CB  . PRO E 5 363 ? 115.494 133.046 109.768 1.00 106.80 ? 310 PRO R CB  1 
ATOM 8148 C CG  . PRO E 5 363 ? 114.918 131.893 109.019 1.00 103.90 ? 310 PRO R CG  1 
ATOM 8149 C CD  . PRO E 5 363 ? 115.914 130.772 109.139 1.00 103.04 ? 310 PRO R CD  1 
ATOM 8150 N N   . ALA E 5 364 ? 116.061 132.154 113.336 1.00 109.08 ? 311 ALA R N   1 
ATOM 8151 C CA  . ALA E 5 364 ? 115.339 132.004 114.596 1.00 108.98 ? 311 ALA R CA  1 
ATOM 8152 C C   . ALA E 5 364 ? 114.453 133.207 114.893 1.00 110.24 ? 311 ALA R C   1 
ATOM 8153 O O   . ALA E 5 364 ? 113.438 133.074 115.586 1.00 106.93 ? 311 ALA R O   1 
ATOM 8154 C CB  . ALA E 5 364 ? 116.326 131.777 115.742 1.00 105.60 ? 311 ALA R CB  1 
ATOM 8155 N N   . SER E 5 365 ? 114.818 134.386 114.383 1.00 120.37 ? 312 SER R N   1 
ATOM 8156 C CA  . SER E 5 365 ? 114.003 135.577 114.591 1.00 120.98 ? 312 SER R CA  1 
ATOM 8157 C C   . SER E 5 365 ? 112.671 135.511 113.855 1.00 121.11 ? 312 SER R C   1 
ATOM 8158 O O   . SER E 5 365 ? 111.753 136.265 114.194 1.00 120.10 ? 312 SER R O   1 
ATOM 8159 C CB  . SER E 5 365 ? 114.773 136.824 114.154 1.00 119.03 ? 312 SER R CB  1 
ATOM 8160 O OG  . SER E 5 365 ? 115.123 136.753 112.782 1.00 118.95 ? 312 SER R OG  1 
ATOM 8161 N N   . GLN E 5 366 ? 112.544 134.634 112.862 1.00 105.03 ? 313 GLN R N   1 
ATOM 8162 C CA  . GLN E 5 366 ? 111.303 134.531 112.109 1.00 100.89 ? 313 GLN R CA  1 
ATOM 8163 C C   . GLN E 5 366 ? 110.218 133.865 112.950 1.00 99.98  ? 313 GLN R C   1 
ATOM 8164 O O   . GLN E 5 366 ? 110.496 133.070 113.852 1.00 97.49  ? 313 GLN R O   1 
ATOM 8165 C CB  . GLN E 5 366 ? 111.529 133.745 110.816 1.00 101.19 ? 313 GLN R CB  1 
ATOM 8166 C CG  . GLN E 5 366 ? 110.369 133.802 109.835 1.00 102.92 ? 313 GLN R CG  1 
ATOM 8167 C CD  . GLN E 5 366 ? 110.641 133.033 108.559 1.00 103.19 ? 313 GLN R CD  1 
ATOM 8168 O OE1 . GLN E 5 366 ? 111.787 132.719 108.240 1.00 99.65  ? 313 GLN R OE1 1 
ATOM 8169 N NE2 . GLN E 5 366 ? 109.583 132.728 107.817 1.00 99.51  ? 313 GLN R NE2 1 
ATOM 8170 N N   . ARG E 5 367 ? 108.963 134.207 112.643 1.00 94.46  ? 314 ARG R N   1 
ATOM 8171 C CA  . ARG E 5 367 ? 107.832 133.631 113.363 1.00 96.33  ? 314 ARG R CA  1 
ATOM 8172 C C   . ARG E 5 367 ? 107.736 132.127 113.139 1.00 97.28  ? 314 ARG R C   1 
ATOM 8173 O O   . ARG E 5 367 ? 107.359 131.379 114.049 1.00 97.07  ? 314 ARG R O   1 
ATOM 8174 C CB  . ARG E 5 367 ? 106.535 134.321 112.939 1.00 93.54  ? 314 ARG R CB  1 
ATOM 8175 N N   . SER E 5 368 ? 108.065 131.666 111.929 1.00 87.02  ? 315 SER R N   1 
ATOM 8176 C CA  . SER E 5 368 ? 107.904 130.253 111.599 1.00 84.91  ? 315 SER R CA  1 
ATOM 8177 C C   . SER E 5 368 ? 108.788 129.371 112.472 1.00 83.04  ? 315 SER R C   1 
ATOM 8178 O O   . SER E 5 368 ? 108.358 128.302 112.922 1.00 81.12  ? 315 SER R O   1 
ATOM 8179 C CB  . SER E 5 368 ? 108.212 130.019 110.121 1.00 85.28  ? 315 SER R CB  1 
ATOM 8180 O OG  . SER E 5 368 ? 109.556 130.355 109.822 1.00 87.12  ? 315 SER R OG  1 
ATOM 8181 N N   . ILE E 5 369 ? 110.028 129.798 112.721 1.00 91.25  ? 316 ILE R N   1 
ATOM 8182 C CA  . ILE E 5 369 ? 110.937 128.991 113.529 1.00 89.84  ? 316 ILE R CA  1 
ATOM 8183 C C   . ILE E 5 369 ? 110.469 128.945 114.978 1.00 90.74  ? 316 ILE R C   1 
ATOM 8184 O O   . ILE E 5 369 ? 110.473 127.882 115.612 1.00 89.18  ? 316 ILE R O   1 
ATOM 8185 C CB  . ILE E 5 369 ? 112.376 129.527 113.412 1.00 90.80  ? 316 ILE R CB  1 
ATOM 8186 C CG1 . ILE E 5 369 ? 112.873 129.408 111.970 1.00 91.38  ? 316 ILE R CG1 1 
ATOM 8187 C CG2 . ILE E 5 369 ? 113.304 128.778 114.355 1.00 88.45  ? 316 ILE R CG2 1 
ATOM 8188 C CD1 . ILE E 5 369 ? 112.922 127.986 111.456 1.00 87.44  ? 316 ILE R CD1 1 
ATOM 8189 N N   . ARG E 5 370 ? 110.064 130.093 115.529 1.00 91.06  ? 317 ARG R N   1 
ATOM 8190 C CA  . ARG E 5 370 ? 109.546 130.109 116.893 1.00 86.82  ? 317 ARG R CA  1 
ATOM 8191 C C   . ARG E 5 370 ? 108.257 129.306 117.006 1.00 84.11  ? 317 ARG R C   1 
ATOM 8192 O O   . ARG E 5 370 ? 108.070 128.550 117.967 1.00 87.13  ? 317 ARG R O   1 
ATOM 8193 C CB  . ARG E 5 370 ? 109.324 131.550 117.353 1.00 87.03  ? 317 ARG R CB  1 
ATOM 8194 N N   . LEU E 5 371 ? 107.347 129.463 116.039 1.00 74.98  ? 318 LEU R N   1 
ATOM 8195 C CA  . LEU E 5 371 ? 106.119 128.674 116.052 1.00 76.59  ? 318 LEU R CA  1 
ATOM 8196 C C   . LEU E 5 371 ? 106.412 127.190 115.882 1.00 79.84  ? 318 LEU R C   1 
ATOM 8197 O O   . LEU E 5 371 ? 105.642 126.344 116.353 1.00 80.41  ? 318 LEU R O   1 
ATOM 8198 C CB  . LEU E 5 371 ? 105.171 129.163 114.957 1.00 78.13  ? 318 LEU R CB  1 
ATOM 8199 C CG  . LEU E 5 371 ? 103.833 128.435 114.804 1.00 78.30  ? 318 LEU R CG  1 
ATOM 8200 C CD1 . LEU E 5 371 ? 103.024 128.526 116.087 1.00 80.15  ? 318 LEU R CD1 1 
ATOM 8201 C CD2 . LEU E 5 371 ? 103.047 128.995 113.628 1.00 79.39  ? 318 LEU R CD2 1 
ATOM 8202 N N   . ARG E 5 372 ? 107.523 126.855 115.224 1.00 80.75  ? 319 ARG R N   1 
ATOM 8203 C CA  . ARG E 5 372 ? 107.884 125.454 115.038 1.00 78.80  ? 319 ARG R CA  1 
ATOM 8204 C C   . ARG E 5 372 ? 108.359 124.838 116.347 1.00 76.04  ? 319 ARG R C   1 
ATOM 8205 O O   . ARG E 5 372 ? 107.988 123.707 116.680 1.00 81.15  ? 319 ARG R O   1 
ATOM 8206 C CB  . ARG E 5 372 ? 108.951 125.328 113.949 1.00 78.93  ? 319 ARG R CB  1 
ATOM 8207 C CG  . ARG E 5 372 ? 109.331 123.900 113.597 1.00 72.26  ? 319 ARG R CG  1 
ATOM 8208 C CD  . ARG E 5 372 ? 110.787 123.806 113.171 1.00 70.87  ? 319 ARG R CD  1 
ATOM 8209 N NE  . ARG E 5 372 ? 110.970 124.168 111.770 1.00 74.56  ? 319 ARG R NE  1 
ATOM 8210 C CZ  . ARG E 5 372 ? 112.134 124.136 111.135 1.00 77.03  ? 319 ARG R CZ  1 
ATOM 8211 N NH1 . ARG E 5 372 ? 113.246 123.761 111.746 1.00 75.91  ? 319 ARG R NH1 1 
ATOM 8212 N NH2 . ARG E 5 372 ? 112.183 124.488 109.853 1.00 74.96  ? 319 ARG R NH2 1 
ATOM 8213 N N   . THR E 5 373 ? 109.183 125.571 117.101 1.00 70.36  ? 320 THR R N   1 
ATOM 8214 C CA  . THR E 5 373 ? 109.698 125.061 118.368 1.00 72.87  ? 320 THR R CA  1 
ATOM 8215 C C   . THR E 5 373 ? 108.616 125.000 119.440 1.00 71.65  ? 320 THR R C   1 
ATOM 8216 O O   . THR E 5 373 ? 108.650 124.113 120.299 1.00 69.60  ? 320 THR R O   1 
ATOM 8217 C CB  . THR E 5 373 ? 110.865 125.929 118.845 1.00 73.38  ? 320 THR R CB  1 
ATOM 8218 O OG1 . THR E 5 373 ? 111.808 126.093 117.778 1.00 74.30  ? 320 THR R OG1 1 
ATOM 8219 C CG2 . THR E 5 373 ? 111.565 125.288 120.036 1.00 69.37  ? 320 THR R CG2 1 
ATOM 8220 N N   . LYS E 5 374 ? 107.646 125.917 119.401 1.00 78.53  ? 321 LYS R N   1 
ATOM 8221 C CA  . LYS E 5 374 ? 106.600 125.928 120.420 1.00 78.62  ? 321 LYS R CA  1 
ATOM 8222 C C   . LYS E 5 374 ? 105.738 124.672 120.358 1.00 80.47  ? 321 LYS R C   1 
ATOM 8223 O O   . LYS E 5 374 ? 105.416 124.085 121.398 1.00 81.29  ? 321 LYS R O   1 
ATOM 8224 C CB  . LYS E 5 374 ? 105.734 127.178 120.265 1.00 77.85  ? 321 LYS R CB  1 
ATOM 8225 C CG  . LYS E 5 374 ? 104.656 127.325 121.325 1.00 77.89  ? 321 LYS R CG  1 
ATOM 8226 C CD  . LYS E 5 374 ? 103.868 128.611 121.135 1.00 79.31  ? 321 LYS R CD  1 
ATOM 8227 C CE  . LYS E 5 374 ? 102.773 128.745 122.180 1.00 82.01  ? 321 LYS R CE  1 
ATOM 8228 N NZ  . LYS E 5 374 ? 101.995 130.001 122.006 1.00 79.80  ? 321 LYS R NZ  1 
ATOM 8229 N N   . ARG E 5 375 ? 105.350 124.244 119.154 1.00 77.02  ? 322 ARG R N   1 
ATOM 8230 C CA  . ARG E 5 375 ? 104.494 123.066 119.047 1.00 77.76  ? 322 ARG R CA  1 
ATOM 8231 C C   . ARG E 5 375 ? 105.249 121.792 119.408 1.00 76.23  ? 322 ARG R C   1 
ATOM 8232 O O   . ARG E 5 375 ? 104.692 120.898 120.056 1.00 74.16  ? 322 ARG R O   1 
ATOM 8233 C CB  . ARG E 5 375 ? 103.907 122.961 117.640 1.00 71.96  ? 322 ARG R CB  1 
ATOM 8234 C CG  . ARG E 5 375 ? 102.906 124.052 117.302 1.00 74.77  ? 322 ARG R CG  1 
ATOM 8235 C CD  . ARG E 5 375 ? 102.250 123.792 115.958 1.00 79.00  ? 322 ARG R CD  1 
ATOM 8236 N NE  . ARG E 5 375 ? 101.220 124.778 115.656 1.00 82.36  ? 322 ARG R NE  1 
ATOM 8237 C CZ  . ARG E 5 375 ? 100.452 124.751 114.576 1.00 79.28  ? 322 ARG R CZ  1 
ATOM 8238 N NH1 . ARG E 5 375 ? 100.569 123.796 113.668 1.00 72.49  ? 322 ARG R NH1 1 
ATOM 8239 N NH2 . ARG E 5 375 ? 99.540  125.704 114.404 1.00 81.84  ? 322 ARG R NH2 1 
ATOM 8240 N N   . VAL E 5 376 ? 106.515 121.690 118.999 1.00 66.94  ? 323 VAL R N   1 
ATOM 8241 C CA  . VAL E 5 376 ? 107.304 120.506 119.322 1.00 62.60  ? 323 VAL R CA  1 
ATOM 8242 C C   . VAL E 5 376 ? 107.605 120.451 120.816 1.00 71.85  ? 323 VAL R C   1 
ATOM 8243 O O   . VAL E 5 376 ? 107.636 119.369 121.416 1.00 72.88  ? 323 VAL R O   1 
ATOM 8244 C CB  . VAL E 5 376 ? 108.591 120.475 118.477 1.00 57.76  ? 323 VAL R CB  1 
ATOM 8245 C CG1 . VAL E 5 376 ? 109.417 119.242 118.803 1.00 54.61  ? 323 VAL R CG1 1 
ATOM 8246 C CG2 . VAL E 5 376 ? 108.248 120.500 116.999 1.00 63.70  ? 323 VAL R CG2 1 
ATOM 8247 N N   . THR E 5 377 ? 107.825 121.612 121.441 1.00 74.57  ? 324 THR R N   1 
ATOM 8248 C CA  . THR E 5 377 ? 108.115 121.635 122.872 1.00 66.37  ? 324 THR R CA  1 
ATOM 8249 C C   . THR E 5 377 ? 106.939 121.106 123.683 1.00 66.09  ? 324 THR R C   1 
ATOM 8250 O O   . THR E 5 377 ? 107.127 120.338 124.634 1.00 70.73  ? 324 THR R O   1 
ATOM 8251 C CB  . THR E 5 377 ? 108.476 123.052 123.318 1.00 69.55  ? 324 THR R CB  1 
ATOM 8252 O OG1 . THR E 5 377 ? 109.578 123.531 122.539 1.00 77.18  ? 324 THR R OG1 1 
ATOM 8253 C CG2 . THR E 5 377 ? 108.862 123.066 124.789 1.00 68.05  ? 324 THR R CG2 1 
ATOM 8254 N N   . ARG E 5 378 ? 105.716 121.495 123.320 1.00 68.71  ? 325 ARG R N   1 
ATOM 8255 C CA  . ARG E 5 378 ? 104.551 121.021 124.052 1.00 73.88  ? 325 ARG R CA  1 
ATOM 8256 C C   . ARG E 5 378 ? 104.187 119.587 123.699 1.00 72.27  ? 325 ARG R C   1 
ATOM 8257 O O   . ARG E 5 378 ? 103.398 118.971 124.422 1.00 72.23  ? 325 ARG R O   1 
ATOM 8258 C CB  . ARG E 5 378 ? 103.345 121.930 123.803 1.00 72.54  ? 325 ARG R CB  1 
ATOM 8259 C CG  . ARG E 5 378 ? 102.618 121.668 122.498 1.00 68.85  ? 325 ARG R CG  1 
ATOM 8260 C CD  . ARG E 5 378 ? 101.164 122.100 122.601 1.00 72.50  ? 325 ARG R CD  1 
ATOM 8261 N NE  . ARG E 5 378 ? 100.438 121.909 121.352 1.00 77.11  ? 325 ARG R NE  1 
ATOM 8262 C CZ  . ARG E 5 378 ? 100.136 122.883 120.506 1.00 78.79  ? 325 ARG R CZ  1 
ATOM 8263 N NH1 . ARG E 5 378 ? 100.475 124.139 120.748 1.00 72.80  ? 325 ARG R NH1 1 
ATOM 8264 N NH2 . ARG E 5 378 ? 99.471  122.591 119.392 1.00 78.74  ? 325 ARG R NH2 1 
ATOM 8265 N N   . THR E 5 379 ? 104.737 119.045 122.612 1.00 66.08  ? 326 THR R N   1 
ATOM 8266 C CA  . THR E 5 379 ? 104.567 117.633 122.295 1.00 62.64  ? 326 THR R CA  1 
ATOM 8267 C C   . THR E 5 379 ? 105.599 116.765 123.003 1.00 60.76  ? 326 THR R C   1 
ATOM 8268 O O   . THR E 5 379 ? 105.274 115.662 123.455 1.00 70.61  ? 326 THR R O   1 
ATOM 8269 C CB  . THR E 5 379 ? 104.661 117.421 120.780 1.00 63.36  ? 326 THR R CB  1 
ATOM 8270 O OG1 . THR E 5 379 ? 103.620 118.155 120.124 1.00 71.65  ? 326 THR R OG1 1 
ATOM 8271 C CG2 . THR E 5 379 ? 104.543 115.944 120.423 1.00 56.68  ? 326 THR R CG2 1 
ATOM 8272 N N   . ALA E 5 380 ? 106.836 117.249 123.128 1.00 53.05  ? 327 ALA R N   1 
ATOM 8273 C CA  . ALA E 5 380 ? 107.837 116.509 123.886 1.00 55.32  ? 327 ALA R CA  1 
ATOM 8274 C C   . ALA E 5 380 ? 107.507 116.493 125.373 1.00 63.92  ? 327 ALA R C   1 
ATOM 8275 O O   . ALA E 5 380 ? 107.734 115.487 126.056 1.00 63.95  ? 327 ALA R O   1 
ATOM 8276 C CB  . ALA E 5 380 ? 109.221 117.110 123.650 1.00 52.06  ? 327 ALA R CB  1 
ATOM 8277 N N   . ILE E 5 381 ? 106.971 117.600 125.892 1.00 67.01  ? 328 ILE R N   1 
ATOM 8278 C CA  . ILE E 5 381 ? 106.553 117.643 127.290 1.00 59.61  ? 328 ILE R CA  1 
ATOM 8279 C C   . ILE E 5 381 ? 105.361 116.724 127.529 1.00 64.41  ? 328 ILE R C   1 
ATOM 8280 O O   . ILE E 5 381 ? 105.328 115.973 128.510 1.00 71.84  ? 328 ILE R O   1 
ATOM 8281 C CB  . ILE E 5 381 ? 106.251 119.092 127.717 1.00 61.61  ? 328 ILE R CB  1 
ATOM 8282 C CG1 . ILE E 5 381 ? 107.548 119.899 127.811 1.00 65.65  ? 328 ILE R CG1 1 
ATOM 8283 C CG2 . ILE E 5 381 ? 105.511 119.117 129.044 1.00 60.75  ? 328 ILE R CG2 1 
ATOM 8284 C CD1 . ILE E 5 381 ? 107.347 121.337 128.237 1.00 69.71  ? 328 ILE R CD1 1 
ATOM 8285 N N   . ALA E 5 382 ? 104.370 116.760 126.634 1.00 61.59  ? 329 ALA R N   1 
ATOM 8286 C CA  . ALA E 5 382 ? 103.169 115.953 126.825 1.00 65.96  ? 329 ALA R CA  1 
ATOM 8287 C C   . ALA E 5 382 ? 103.476 114.461 126.781 1.00 67.86  ? 329 ALA R C   1 
ATOM 8288 O O   . ALA E 5 382 ? 102.924 113.686 127.570 1.00 66.61  ? 329 ALA R O   1 
ATOM 8289 C CB  . ALA E 5 382 ? 102.122 116.315 125.772 1.00 59.17  ? 329 ALA R CB  1 
ATOM 8290 N N   . ILE E 5 383 ? 104.349 114.038 125.866 1.00 64.79  ? 330 ILE R N   1 
ATOM 8291 C CA  . ILE E 5 383 ? 104.678 112.619 125.754 1.00 59.21  ? 330 ILE R CA  1 
ATOM 8292 C C   . ILE E 5 383 ? 105.413 112.135 126.998 1.00 65.00  ? 330 ILE R C   1 
ATOM 8293 O O   . ILE E 5 383 ? 105.100 111.073 127.550 1.00 74.17  ? 330 ILE R O   1 
ATOM 8294 C CB  . ILE E 5 383 ? 105.491 112.358 124.473 1.00 57.55  ? 330 ILE R CB  1 
ATOM 8295 C CG1 . ILE E 5 383 ? 104.597 112.549 123.247 1.00 63.63  ? 330 ILE R CG1 1 
ATOM 8296 C CG2 . ILE E 5 383 ? 106.101 110.966 124.494 1.00 57.20  ? 330 ILE R CG2 1 
ATOM 8297 C CD1 . ILE E 5 383 ? 105.306 112.381 121.932 1.00 64.13  ? 330 ILE R CD1 1 
ATOM 8298 N N   . CYS E 5 384 ? 106.395 112.908 127.464 1.00 63.05  ? 331 CYS R N   1 
ATOM 8299 C CA  . CYS E 5 384 ? 107.148 112.501 128.645 1.00 68.36  ? 331 CYS R CA  1 
ATOM 8300 C C   . CYS E 5 384 ? 106.288 112.563 129.902 1.00 68.28  ? 331 CYS R C   1 
ATOM 8301 O O   . CYS E 5 384 ? 106.423 111.717 130.794 1.00 64.58  ? 331 CYS R O   1 
ATOM 8302 C CB  . CYS E 5 384 ? 108.393 113.374 128.797 1.00 68.12  ? 331 CYS R CB  1 
ATOM 8303 S SG  . CYS E 5 384 ? 109.586 113.201 127.450 1.00 71.03  ? 331 CYS R SG  1 
ATOM 8304 N N   . LEU E 5 385 ? 105.400 113.557 129.995 1.00 69.13  ? 332 LEU R N   1 
ATOM 8305 C CA  . LEU E 5 385 ? 104.610 113.721 131.211 1.00 68.53  ? 332 LEU R CA  1 
ATOM 8306 C C   . LEU E 5 385 ? 103.506 112.674 131.308 1.00 75.05  ? 332 LEU R C   1 
ATOM 8307 O O   . LEU E 5 385 ? 103.256 112.131 132.390 1.00 80.06  ? 332 LEU R O   1 
ATOM 8308 C CB  . LEU E 5 385 ? 104.018 115.129 131.263 1.00 62.70  ? 332 LEU R CB  1 
ATOM 8309 C CG  . LEU E 5 385 ? 103.286 115.525 132.545 1.00 65.35  ? 332 LEU R CG  1 
ATOM 8310 C CD1 . LEU E 5 385 ? 104.238 115.538 133.731 1.00 68.40  ? 332 LEU R CD1 1 
ATOM 8311 C CD2 . LEU E 5 385 ? 102.612 116.877 132.377 1.00 67.88  ? 332 LEU R CD2 1 
ATOM 8312 N N   . VAL E 5 386 ? 102.836 112.377 130.191 1.00 69.93  ? 333 VAL R N   1 
ATOM 8313 C CA  . VAL E 5 386 ? 101.771 111.375 130.204 1.00 69.26  ? 333 VAL R CA  1 
ATOM 8314 C C   . VAL E 5 386 ? 102.331 110.006 130.567 1.00 66.80  ? 333 VAL R C   1 
ATOM 8315 O O   . VAL E 5 386 ? 101.724 109.252 131.339 1.00 68.93  ? 333 VAL R O   1 
ATOM 8316 C CB  . VAL E 5 386 ? 101.038 111.352 128.848 1.00 69.60  ? 333 VAL R CB  1 
ATOM 8317 C CG1 . VAL E 5 386 ? 100.211 110.083 128.705 1.00 67.29  ? 333 VAL R CG1 1 
ATOM 8318 C CG2 . VAL E 5 386 ? 100.152 112.579 128.708 1.00 71.21  ? 333 VAL R CG2 1 
ATOM 8319 N N   . PHE E 5 387 ? 103.505 109.670 130.028 1.00 64.06  ? 334 PHE R N   1 
ATOM 8320 C CA  . PHE E 5 387 ? 104.153 108.410 130.377 1.00 67.25  ? 334 PHE R CA  1 
ATOM 8321 C C   . PHE E 5 387 ? 104.507 108.362 131.859 1.00 74.99  ? 334 PHE R C   1 
ATOM 8322 O O   . PHE E 5 387 ? 104.342 107.324 132.510 1.00 84.39  ? 334 PHE R O   1 
ATOM 8323 C CB  . PHE E 5 387 ? 105.400 108.209 129.516 1.00 69.64  ? 334 PHE R CB  1 
ATOM 8324 C CG  . PHE E 5 387 ? 106.146 106.941 129.814 1.00 67.71  ? 334 PHE R CG  1 
ATOM 8325 C CD1 . PHE E 5 387 ? 105.716 105.731 129.299 1.00 70.64  ? 334 PHE R CD1 1 
ATOM 8326 C CD2 . PHE E 5 387 ? 107.283 106.962 130.603 1.00 66.63  ? 334 PHE R CD2 1 
ATOM 8327 C CE1 . PHE E 5 387 ? 106.402 104.567 129.571 1.00 75.38  ? 334 PHE R CE1 1 
ATOM 8328 C CE2 . PHE E 5 387 ? 107.972 105.800 130.878 1.00 69.75  ? 334 PHE R CE2 1 
ATOM 8329 C CZ  . PHE E 5 387 ? 107.532 104.602 130.362 1.00 72.33  ? 334 PHE R CZ  1 
ATOM 8330 N N   . PHE E 5 388 ? 105.001 109.474 132.407 1.00 77.20  ? 335 PHE R N   1 
ATOM 8331 C CA  . PHE E 5 388 ? 105.384 109.502 133.815 1.00 79.69  ? 335 PHE R CA  1 
ATOM 8332 C C   . PHE E 5 388 ? 104.165 109.405 134.725 1.00 77.36  ? 335 PHE R C   1 
ATOM 8333 O O   . PHE E 5 388 ? 104.146 108.607 135.669 1.00 81.18  ? 335 PHE R O   1 
ATOM 8334 C CB  . PHE E 5 388 ? 106.178 110.772 134.116 1.00 78.92  ? 335 PHE R CB  1 
ATOM 8335 C CG  . PHE E 5 388 ? 106.750 110.815 135.503 1.00 77.22  ? 335 PHE R CG  1 
ATOM 8336 C CD1 . PHE E 5 388 ? 107.930 110.154 135.800 1.00 74.21  ? 335 PHE R CD1 1 
ATOM 8337 C CD2 . PHE E 5 388 ? 106.111 111.519 136.508 1.00 76.26  ? 335 PHE R CD2 1 
ATOM 8338 C CE1 . PHE E 5 388 ? 108.459 110.193 137.074 1.00 76.20  ? 335 PHE R CE1 1 
ATOM 8339 C CE2 . PHE E 5 388 ? 106.634 111.561 137.784 1.00 76.93  ? 335 PHE R CE2 1 
ATOM 8340 C CZ  . PHE E 5 388 ? 107.810 110.897 138.067 1.00 78.32  ? 335 PHE R CZ  1 
ATOM 8341 N N   . VAL E 5 389 ? 103.134 110.209 134.454 1.00 72.56  ? 336 VAL R N   1 
ATOM 8342 C CA  . VAL E 5 389 ? 101.976 110.267 135.342 1.00 75.10  ? 336 VAL R CA  1 
ATOM 8343 C C   . VAL E 5 389 ? 101.231 108.937 135.371 1.00 82.45  ? 336 VAL R C   1 
ATOM 8344 O O   . VAL E 5 389 ? 100.711 108.534 136.419 1.00 85.12  ? 336 VAL R O   1 
ATOM 8345 C CB  . VAL E 5 389 ? 101.051 111.427 134.924 1.00 74.54  ? 336 VAL R CB  1 
ATOM 8346 C CG1 . VAL E 5 389 ? 99.744  111.385 135.700 1.00 77.61  ? 336 VAL R CG1 1 
ATOM 8347 C CG2 . VAL E 5 389 ? 101.746 112.763 135.137 1.00 77.06  ? 336 VAL R CG2 1 
ATOM 8348 N N   . CYS E 5 390 ? 101.180 108.224 134.247 1.00 88.41  ? 337 CYS R N   1 
ATOM 8349 C CA  . CYS E 5 390 ? 100.395 106.998 134.177 1.00 88.20  ? 337 CYS R CA  1 
ATOM 8350 C C   . CYS E 5 390 ? 101.104 105.780 134.758 1.00 86.74  ? 337 CYS R C   1 
ATOM 8351 O O   . CYS E 5 390 ? 100.444 104.761 134.989 1.00 89.01  ? 337 CYS R O   1 
ATOM 8352 C CB  . CYS E 5 390 ? 100.004 106.714 132.725 1.00 91.12  ? 337 CYS R CB  1 
ATOM 8353 S SG  . CYS E 5 390 ? 98.843  107.908 132.020 1.00 102.32 ? 337 CYS R SG  1 
ATOM 8354 N N   . TRP E 5 391 ? 102.415 105.845 134.999 1.00 83.65  ? 338 TRP R N   1 
ATOM 8355 C CA  . TRP E 5 391 ? 103.151 104.693 135.510 1.00 85.62  ? 338 TRP R CA  1 
ATOM 8356 C C   . TRP E 5 391 ? 103.945 104.949 136.785 1.00 90.52  ? 338 TRP R C   1 
ATOM 8357 O O   . TRP E 5 391 ? 104.356 103.974 137.427 1.00 94.16  ? 338 TRP R O   1 
ATOM 8358 C CB  . TRP E 5 391 ? 104.112 104.146 134.443 1.00 82.84  ? 338 TRP R CB  1 
ATOM 8359 C CG  . TRP E 5 391 ? 103.429 103.391 133.348 1.00 88.07  ? 338 TRP R CG  1 
ATOM 8360 C CD1 . TRP E 5 391 ? 103.300 103.770 132.044 1.00 86.71  ? 338 TRP R CD1 1 
ATOM 8361 C CD2 . TRP E 5 391 ? 102.776 102.121 133.463 1.00 92.27  ? 338 TRP R CD2 1 
ATOM 8362 N NE1 . TRP E 5 391 ? 102.610 102.814 131.339 1.00 88.78  ? 338 TRP R NE1 1 
ATOM 8363 C CE2 . TRP E 5 391 ? 102.276 101.792 132.187 1.00 92.73  ? 338 TRP R CE2 1 
ATOM 8364 C CE3 . TRP E 5 391 ? 102.566 101.230 134.520 1.00 87.97  ? 338 TRP R CE3 1 
ATOM 8365 C CZ2 . TRP E 5 391 ? 101.579 100.610 131.941 1.00 88.84  ? 338 TRP R CZ2 1 
ATOM 8366 C CZ3 . TRP E 5 391 ? 101.875 100.059 134.274 1.00 83.72  ? 338 TRP R CZ3 1 
ATOM 8367 C CH2 . TRP E 5 391 ? 101.389 99.759  132.995 1.00 82.80  ? 338 TRP R CH2 1 
ATOM 8368 N N   . ALA E 5 392 ? 104.182 106.206 137.174 1.00 92.35  ? 339 ALA R N   1 
ATOM 8369 C CA  . ALA E 5 392 ? 104.897 106.456 138.427 1.00 92.24  ? 339 ALA R CA  1 
ATOM 8370 C C   . ALA E 5 392 ? 104.120 105.986 139.652 1.00 91.91  ? 339 ALA R C   1 
ATOM 8371 O O   . ALA E 5 392 ? 104.709 105.285 140.494 1.00 94.41  ? 339 ALA R O   1 
ATOM 8372 C CB  . ALA E 5 392 ? 105.276 107.937 138.529 1.00 92.72  ? 339 ALA R CB  1 
ATOM 8373 N N   . PRO E 5 393 ? 102.836 106.325 139.833 1.00 92.22  ? 340 PRO R N   1 
ATOM 8374 C CA  . PRO E 5 393 ? 102.123 105.837 141.027 1.00 93.16  ? 340 PRO R CA  1 
ATOM 8375 C C   . PRO E 5 393 ? 102.062 104.324 141.133 1.00 92.25  ? 340 PRO R C   1 
ATOM 8376 O O   . PRO E 5 393 ? 102.060 103.792 142.250 1.00 91.99  ? 340 PRO R O   1 
ATOM 8377 C CB  . PRO E 5 393 ? 100.722 106.447 140.874 1.00 91.51  ? 340 PRO R CB  1 
ATOM 8378 C CG  . PRO E 5 393 ? 100.591 106.737 139.427 1.00 88.58  ? 340 PRO R CG  1 
ATOM 8379 C CD  . PRO E 5 393 ? 101.955 107.156 138.993 1.00 88.75  ? 340 PRO R CD  1 
ATOM 8380 N N   . TYR E 5 394 ? 102.005 103.612 140.005 1.00 105.48 ? 341 TYR R N   1 
ATOM 8381 C CA  . TYR E 5 394 ? 101.995 102.153 140.054 1.00 105.65 ? 341 TYR R CA  1 
ATOM 8382 C C   . TYR E 5 394 ? 103.295 101.604 140.628 1.00 107.04 ? 341 TYR R C   1 
ATOM 8383 O O   . TYR E 5 394 ? 103.276 100.656 141.422 1.00 111.66 ? 341 TYR R O   1 
ATOM 8384 C CB  . TYR E 5 394 ? 101.741 101.574 138.663 1.00 108.77 ? 341 TYR R CB  1 
ATOM 8385 C CG  . TYR E 5 394 ? 101.607 100.068 138.666 1.00 109.84 ? 341 TYR R CG  1 
ATOM 8386 C CD1 . TYR E 5 394 ? 100.407 99.459  139.008 1.00 108.84 ? 341 TYR R CD1 1 
ATOM 8387 C CD2 . TYR E 5 394 ? 102.684 99.255  138.338 1.00 109.43 ? 341 TYR R CD2 1 
ATOM 8388 C CE1 . TYR E 5 394 ? 100.282 98.083  139.017 1.00 108.10 ? 341 TYR R CE1 1 
ATOM 8389 C CE2 . TYR E 5 394 ? 102.568 97.878  138.345 1.00 109.14 ? 341 TYR R CE2 1 
ATOM 8390 C CZ  . TYR E 5 394 ? 101.365 97.298  138.685 1.00 108.64 ? 341 TYR R CZ  1 
ATOM 8391 O OH  . TYR E 5 394 ? 101.244 95.928  138.693 1.00 108.58 ? 341 TYR R OH  1 
ATOM 8392 N N   . TYR E 5 395 ? 104.432 102.179 140.242 1.00 96.79  ? 342 TYR R N   1 
ATOM 8393 C CA  . TYR E 5 395 ? 105.719 101.684 140.709 1.00 99.35  ? 342 TYR R CA  1 
ATOM 8394 C C   . TYR E 5 395 ? 106.180 102.349 141.998 1.00 103.38 ? 342 TYR R C   1 
ATOM 8395 O O   . TYR E 5 395 ? 107.175 101.907 142.582 1.00 106.76 ? 342 TYR R O   1 
ATOM 8396 C CB  . TYR E 5 395 ? 106.786 101.869 139.625 1.00 95.83  ? 342 TYR R CB  1 
ATOM 8397 C CG  . TYR E 5 395 ? 106.665 100.887 138.480 1.00 96.61  ? 342 TYR R CG  1 
ATOM 8398 C CD1 . TYR E 5 395 ? 105.875 101.170 137.375 1.00 99.71  ? 342 TYR R CD1 1 
ATOM 8399 C CD2 . TYR E 5 395 ? 107.334 99.671  138.512 1.00 98.09  ? 342 TYR R CD2 1 
ATOM 8400 C CE1 . TYR E 5 395 ? 105.760 100.272 136.329 1.00 101.02 ? 342 TYR R CE1 1 
ATOM 8401 C CE2 . TYR E 5 395 ? 107.226 98.767  137.472 1.00 98.64  ? 342 TYR R CE2 1 
ATOM 8402 C CZ  . TYR E 5 395 ? 106.438 99.072  136.384 1.00 99.96  ? 342 TYR R CZ  1 
ATOM 8403 O OH  . TYR E 5 395 ? 106.328 98.174  135.347 1.00 102.87 ? 342 TYR R OH  1 
ATOM 8404 N N   . VAL E 5 396 ? 105.489 103.393 142.456 1.00 105.28 ? 343 VAL R N   1 
ATOM 8405 C CA  . VAL E 5 396 ? 105.772 103.947 143.775 1.00 106.03 ? 343 VAL R CA  1 
ATOM 8406 C C   . VAL E 5 396 ? 105.084 103.121 144.854 1.00 105.65 ? 343 VAL R C   1 
ATOM 8407 O O   . VAL E 5 396 ? 105.689 102.773 145.874 1.00 104.33 ? 343 VAL R O   1 
ATOM 8408 C CB  . VAL E 5 396 ? 105.354 105.428 143.837 1.00 103.91 ? 343 VAL R CB  1 
ATOM 8409 C CG1 . VAL E 5 396 ? 105.225 105.888 145.281 1.00 104.62 ? 343 VAL R CG1 1 
ATOM 8410 C CG2 . VAL E 5 396 ? 106.362 106.291 143.093 1.00 102.65 ? 343 VAL R CG2 1 
ATOM 8411 N N   . LEU E 5 397 ? 103.805 102.792 144.644 1.00 113.72 ? 344 LEU R N   1 
ATOM 8412 C CA  . LEU E 5 397 ? 103.123 101.874 145.549 1.00 113.58 ? 344 LEU R CA  1 
ATOM 8413 C C   . LEU E 5 397 ? 103.716 100.474 145.471 1.00 112.42 ? 344 LEU R C   1 
ATOM 8414 O O   . LEU E 5 397 ? 103.666 99.726  146.454 1.00 115.36 ? 344 LEU R O   1 
ATOM 8415 C CB  . LEU E 5 397 ? 101.628 101.838 145.235 1.00 111.99 ? 344 LEU R CB  1 
ATOM 8416 C CG  . LEU E 5 397 ? 100.883 103.170 145.358 1.00 112.95 ? 344 LEU R CG  1 
ATOM 8417 C CD1 . LEU E 5 397 ? 99.419  103.005 144.981 1.00 113.02 ? 344 LEU R CD1 1 
ATOM 8418 C CD2 . LEU E 5 397 ? 101.017 103.739 146.761 1.00 114.09 ? 344 LEU R CD2 1 
ATOM 8419 N N   . GLN E 5 398 ? 104.266 100.099 144.313 1.00 111.68 ? 345 GLN R N   1 
ATOM 8420 C CA  . GLN E 5 398 ? 104.908 98.795  144.183 1.00 115.42 ? 345 GLN R CA  1 
ATOM 8421 C C   . GLN E 5 398 ? 106.121 98.693  145.100 1.00 116.86 ? 345 GLN R C   1 
ATOM 8422 O O   . GLN E 5 398 ? 106.372 97.642  145.699 1.00 118.89 ? 345 GLN R O   1 
ATOM 8423 C CB  . GLN E 5 398 ? 105.300 98.544  142.727 1.00 115.99 ? 345 GLN R CB  1 
ATOM 8424 C CG  . GLN E 5 398 ? 105.315 97.075  142.327 1.00 115.35 ? 345 GLN R CG  1 
ATOM 8425 C CD  . GLN E 5 398 ? 103.922 96.484  142.203 1.00 116.55 ? 345 GLN R CD  1 
ATOM 8426 O OE1 . GLN E 5 398 ? 103.736 95.274  142.335 1.00 116.63 ? 345 GLN R OE1 1 
ATOM 8427 N NE2 . GLN E 5 398 ? 102.938 97.336  141.941 1.00 118.35 ? 345 GLN R NE2 1 
ATOM 8428 N N   . LEU E 5 399 ? 106.913 99.763  145.187 1.00 113.90 ? 346 LEU R N   1 
ATOM 8429 C CA  . LEU E 5 399 ? 108.060 99.758  146.086 1.00 116.29 ? 346 LEU R CA  1 
ATOM 8430 C C   . LEU E 5 399 ? 107.640 99.912  147.543 1.00 117.17 ? 346 LEU R C   1 
ATOM 8431 O O   . LEU E 5 399 ? 108.320 99.402  148.440 1.00 115.56 ? 346 LEU R O   1 
ATOM 8432 C CB  . LEU E 5 399 ? 109.036 100.872 145.703 1.00 116.66 ? 346 LEU R CB  1 
ATOM 8433 C CG  . LEU E 5 399 ? 109.730 100.775 144.343 1.00 115.37 ? 346 LEU R CG  1 
ATOM 8434 C CD1 . LEU E 5 399 ? 110.611 101.992 144.108 1.00 112.97 ? 346 LEU R CD1 1 
ATOM 8435 C CD2 . LEU E 5 399 ? 110.552 99.503  144.259 1.00 116.49 ? 346 LEU R CD2 1 
ATOM 8436 N N   . THR E 5 400 ? 106.531 100.614 147.798 1.00 122.43 ? 347 THR R N   1 
ATOM 8437 C CA  . THR E 5 400 ? 106.063 100.801 149.169 1.00 123.34 ? 347 THR R CA  1 
ATOM 8438 C C   . THR E 5 400 ? 105.612 99.498  149.824 1.00 122.78 ? 347 THR R C   1 
ATOM 8439 O O   . THR E 5 400 ? 105.755 99.346  151.042 1.00 121.25 ? 347 THR R O   1 
ATOM 8440 C CB  . THR E 5 400 ? 104.924 101.823 149.194 1.00 124.27 ? 347 THR R CB  1 
ATOM 8441 O OG1 . THR E 5 400 ? 105.278 102.952 148.387 1.00 123.09 ? 347 THR R OG1 1 
ATOM 8442 C CG2 . THR E 5 400 ? 104.662 102.298 150.616 1.00 123.82 ? 347 THR R CG2 1 
ATOM 8443 N N   . GLN E 5 401 ? 105.070 98.550  149.051 1.00 133.36 ? 348 GLN R N   1 
ATOM 8444 C CA  . GLN E 5 401 ? 104.582 97.315  149.660 1.00 135.25 ? 348 GLN R CA  1 
ATOM 8445 C C   . GLN E 5 401 ? 105.705 96.497  150.286 1.00 136.91 ? 348 GLN R C   1 
ATOM 8446 O O   . GLN E 5 401 ? 105.429 95.621  151.113 1.00 136.31 ? 348 GLN R O   1 
ATOM 8447 C CB  . GLN E 5 401 ? 103.819 96.459  148.645 1.00 136.12 ? 348 GLN R CB  1 
ATOM 8448 C CG  . GLN E 5 401 ? 104.645 95.937  147.493 1.00 136.32 ? 348 GLN R CG  1 
ATOM 8449 C CD  . GLN E 5 401 ? 103.828 95.098  146.529 1.00 136.61 ? 348 GLN R CD  1 
ATOM 8450 O OE1 . GLN E 5 401 ? 102.601 95.189  146.495 1.00 137.81 ? 348 GLN R OE1 1 
ATOM 8451 N NE2 . GLN E 5 401 ? 104.508 94.274  145.741 1.00 134.92 ? 348 GLN R NE2 1 
ATOM 8452 N N   . LEU E 5 402 ? 106.958 96.747  149.898 1.00 143.19 ? 349 LEU R N   1 
ATOM 8453 C CA  . LEU E 5 402 ? 108.076 96.030  150.503 1.00 143.45 ? 349 LEU R CA  1 
ATOM 8454 C C   . LEU E 5 402 ? 108.159 96.306  151.999 1.00 143.17 ? 349 LEU R C   1 
ATOM 8455 O O   . LEU E 5 402 ? 108.379 95.387  152.797 1.00 142.81 ? 349 LEU R O   1 
ATOM 8456 C CB  . LEU E 5 402 ? 109.383 96.417  149.811 1.00 142.10 ? 349 LEU R CB  1 
ATOM 8457 C CG  . LEU E 5 402 ? 109.454 96.162  148.304 1.00 142.61 ? 349 LEU R CG  1 
ATOM 8458 C CD1 . LEU E 5 402 ? 110.804 96.589  147.749 1.00 140.77 ? 349 LEU R CD1 1 
ATOM 8459 C CD2 . LEU E 5 402 ? 109.183 94.699  147.996 1.00 143.21 ? 349 LEU R CD2 1 
ATOM 8460 N N   . SER E 5 403 ? 107.986 97.567  152.399 1.00 144.60 ? 350 SER R N   1 
ATOM 8461 C CA  . SER E 5 403 ? 107.979 97.904  153.817 1.00 143.69 ? 350 SER R CA  1 
ATOM 8462 C C   . SER E 5 403 ? 106.656 97.538  154.477 1.00 144.96 ? 350 SER R C   1 
ATOM 8463 O O   . SER E 5 403 ? 106.636 97.168  155.657 1.00 146.01 ? 350 SER R O   1 
ATOM 8464 C CB  . SER E 5 403 ? 108.266 99.394  154.008 1.00 143.66 ? 350 SER R CB  1 
ATOM 8465 O OG  . SER E 5 403 ? 107.293 100.189 153.353 1.00 142.95 ? 350 SER R OG  1 
ATOM 8466 N N   . ILE E 5 404 ? 105.554 97.637  153.741 1.00 155.91 ? 351 ILE R N   1 
ATOM 8467 C CA  . ILE E 5 404 ? 104.225 97.403  154.294 1.00 157.62 ? 351 ILE R CA  1 
ATOM 8468 C C   . ILE E 5 404 ? 104.022 95.906  154.481 1.00 157.96 ? 351 ILE R C   1 
ATOM 8469 O O   . ILE E 5 404 ? 104.290 95.111  153.573 1.00 155.89 ? 351 ILE R O   1 
ATOM 8470 C CB  . ILE E 5 404 ? 103.143 98.004  153.384 1.00 155.91 ? 351 ILE R CB  1 
ATOM 8471 C CG1 . ILE E 5 404 ? 103.323 99.519  153.268 1.00 154.55 ? 351 ILE R CG1 1 
ATOM 8472 C CG2 . ILE E 5 404 ? 101.754 97.672  153.910 1.00 156.01 ? 351 ILE R CG2 1 
ATOM 8473 C CD1 . ILE E 5 404 ? 102.262 100.197 152.431 1.00 155.35 ? 351 ILE R CD1 1 
ATOM 8474 N N   . SER E 5 405 ? 103.547 95.516  155.662 1.00 164.53 ? 352 SER R N   1 
ATOM 8475 C CA  . SER E 5 405 ? 103.239 94.121  155.954 1.00 163.12 ? 352 SER R CA  1 
ATOM 8476 C C   . SER E 5 405 ? 101.742 93.840  155.928 1.00 163.82 ? 352 SER R C   1 
ATOM 8477 O O   . SER E 5 405 ? 101.306 92.858  155.320 1.00 163.36 ? 352 SER R O   1 
ATOM 8478 C CB  . SER E 5 405 ? 103.823 93.727  157.316 1.00 162.54 ? 352 SER R CB  1 
ATOM 8479 O OG  . SER E 5 405 ? 105.231 93.883  157.331 1.00 161.97 ? 352 SER R OG  1 
ATOM 8480 N N   . ARG E 5 406 ? 100.944 94.683  156.576 1.00 175.01 ? 353 ARG R N   1 
ATOM 8481 C CA  . ARG E 5 406 ? 99.489  94.532  156.597 1.00 175.71 ? 353 ARG R CA  1 
ATOM 8482 C C   . ARG E 5 406 ? 98.853  95.735  155.917 1.00 175.94 ? 353 ARG R C   1 
ATOM 8483 O O   . ARG E 5 406 ? 98.748  96.814  156.529 1.00 175.45 ? 353 ARG R O   1 
ATOM 8484 C CB  . ARG E 5 406 ? 98.976  94.389  158.029 1.00 174.69 ? 353 ARG R CB  1 
ATOM 8485 N N   . PRO E 5 407 ? 98.422  95.612  154.663 1.00 178.07 ? 354 PRO R N   1 
ATOM 8486 C CA  . PRO E 5 407 ? 97.848  96.768  153.967 1.00 177.34 ? 354 PRO R CA  1 
ATOM 8487 C C   . PRO E 5 407 ? 96.507  97.171  154.559 1.00 177.66 ? 354 PRO R C   1 
ATOM 8488 O O   . PRO E 5 407 ? 95.778  96.356  155.128 1.00 177.51 ? 354 PRO R O   1 
ATOM 8489 C CB  . PRO E 5 407 ? 97.693  96.272  152.525 1.00 176.96 ? 354 PRO R CB  1 
ATOM 8490 C CG  . PRO E 5 407 ? 97.565  94.791  152.656 1.00 176.00 ? 354 PRO R CG  1 
ATOM 8491 C CD  . PRO E 5 407 ? 98.439  94.405  153.818 1.00 176.41 ? 354 PRO R CD  1 
ATOM 8492 N N   . THR E 5 408 ? 96.190  98.453  154.416 1.00 174.79 ? 355 THR R N   1 
ATOM 8493 C CA  . THR E 5 408 ? 94.927  99.009  154.874 1.00 174.71 ? 355 THR R CA  1 
ATOM 8494 C C   . THR E 5 408 ? 93.977  99.232  153.700 1.00 173.86 ? 355 THR R C   1 
ATOM 8495 O O   . THR E 5 408 ? 94.333  99.061  152.532 1.00 173.32 ? 355 THR R O   1 
ATOM 8496 C CB  . THR E 5 408 ? 95.158  100.322 155.629 1.00 173.60 ? 355 THR R CB  1 
ATOM 8497 O OG1 . THR E 5 408 ? 93.897  100.888 156.007 1.00 171.68 ? 355 THR R OG1 1 
ATOM 8498 C CG2 . THR E 5 408 ? 95.915  101.311 154.756 1.00 172.95 ? 355 THR R CG2 1 
ATOM 8499 N N   . LEU E 5 409 ? 92.742  99.616  154.037 1.00 164.62 ? 356 LEU R N   1 
ATOM 8500 C CA  . LEU E 5 409 ? 91.718  99.821  153.017 1.00 163.54 ? 356 LEU R CA  1 
ATOM 8501 C C   . LEU E 5 409 ? 92.096  100.954 152.070 1.00 163.68 ? 356 LEU R C   1 
ATOM 8502 O O   . LEU E 5 409 ? 91.895  100.850 150.854 1.00 163.69 ? 356 LEU R O   1 
ATOM 8503 C CB  . LEU E 5 409 ? 90.369  100.101 153.680 1.00 163.52 ? 356 LEU R CB  1 
ATOM 8504 C CG  . LEU E 5 409 ? 89.818  98.987  154.572 1.00 164.14 ? 356 LEU R CG  1 
ATOM 8505 C CD1 . LEU E 5 409 ? 88.472  99.383  155.159 1.00 163.92 ? 356 LEU R CD1 1 
ATOM 8506 C CD2 . LEU E 5 409 ? 89.707  97.683  153.796 1.00 163.43 ? 356 LEU R CD2 1 
ATOM 8507 N N   . THR E 5 410 ? 92.635  102.049 152.613 1.00 165.39 ? 357 THR R N   1 
ATOM 8508 C CA  . THR E 5 410 ? 93.011  103.186 151.778 1.00 165.78 ? 357 THR R CA  1 
ATOM 8509 C C   . THR E 5 410 ? 94.111  102.807 150.795 1.00 164.20 ? 357 THR R C   1 
ATOM 8510 O O   . THR E 5 410 ? 94.098  103.243 149.638 1.00 162.73 ? 357 THR R O   1 
ATOM 8511 C CB  . THR E 5 410 ? 93.455  104.359 152.652 1.00 165.69 ? 357 THR R CB  1 
ATOM 8512 O OG1 . THR E 5 410 ? 94.602  103.977 153.422 1.00 165.41 ? 357 THR R OG1 1 
ATOM 8513 C CG2 . THR E 5 410 ? 92.335  104.775 153.594 1.00 164.54 ? 357 THR R CG2 1 
ATOM 8514 N N   . PHE E 5 411 ? 95.075  101.998 151.239 1.00 163.80 ? 358 PHE R N   1 
ATOM 8515 C CA  . PHE E 5 411 ? 96.135  101.545 150.344 1.00 163.55 ? 358 PHE R CA  1 
ATOM 8516 C C   . PHE E 5 411 ? 95.578  100.667 149.231 1.00 163.29 ? 358 PHE R C   1 
ATOM 8517 O O   . PHE E 5 411 ? 96.061  100.713 148.093 1.00 163.48 ? 358 PHE R O   1 
ATOM 8518 C CB  . PHE E 5 411 ? 97.206  100.795 151.136 1.00 163.95 ? 358 PHE R CB  1 
ATOM 8519 C CG  . PHE E 5 411 ? 98.416  100.433 150.326 1.00 164.77 ? 358 PHE R CG  1 
ATOM 8520 C CD1 . PHE E 5 411 ? 99.410  101.367 150.087 1.00 164.96 ? 358 PHE R CD1 1 
ATOM 8521 C CD2 . PHE E 5 411 ? 98.560  99.158  149.803 1.00 163.13 ? 358 PHE R CD2 1 
ATOM 8522 C CE1 . PHE E 5 411 ? 100.525 101.037 149.341 1.00 164.52 ? 358 PHE R CE1 1 
ATOM 8523 C CE2 . PHE E 5 411 ? 99.673  98.822  149.056 1.00 163.36 ? 358 PHE R CE2 1 
ATOM 8524 C CZ  . PHE E 5 411 ? 100.657 99.763  148.825 1.00 164.17 ? 358 PHE R CZ  1 
ATOM 8525 N N   . VAL E 5 412 ? 94.566  99.853  149.542 1.00 154.76 ? 359 VAL R N   1 
ATOM 8526 C CA  . VAL E 5 412 ? 93.949  99.009  148.522 1.00 154.08 ? 359 VAL R CA  1 
ATOM 8527 C C   . VAL E 5 412 ? 93.279  99.869  147.457 1.00 153.28 ? 359 VAL R C   1 
ATOM 8528 O O   . VAL E 5 412 ? 93.393  99.597  146.255 1.00 151.35 ? 359 VAL R O   1 
ATOM 8529 C CB  . VAL E 5 412 ? 92.955  98.027  149.171 1.00 153.64 ? 359 VAL R CB  1 
ATOM 8530 C CG1 . VAL E 5 412 ? 92.147  97.301  148.107 1.00 153.44 ? 359 VAL R CG1 1 
ATOM 8531 C CG2 . VAL E 5 412 ? 93.695  97.031  150.051 1.00 153.13 ? 359 VAL R CG2 1 
ATOM 8532 N N   . TYR E 5 413 ? 92.571  100.920 147.879 1.00 156.17 ? 360 TYR R N   1 
ATOM 8533 C CA  . TYR E 5 413 ? 91.927  101.813 146.920 1.00 156.49 ? 360 TYR R CA  1 
ATOM 8534 C C   . TYR E 5 413 ? 92.957  102.535 146.061 1.00 156.74 ? 360 TYR R C   1 
ATOM 8535 O O   . TYR E 5 413 ? 92.765  102.695 144.849 1.00 155.98 ? 360 TYR R O   1 
ATOM 8536 C CB  . TYR E 5 413 ? 91.038  102.818 147.652 1.00 156.49 ? 360 TYR R CB  1 
ATOM 8537 C CG  . TYR E 5 413 ? 89.902  102.184 148.423 1.00 157.09 ? 360 TYR R CG  1 
ATOM 8538 C CD1 . TYR E 5 413 ? 89.353  100.974 148.018 1.00 156.43 ? 360 TYR R CD1 1 
ATOM 8539 C CD2 . TYR E 5 413 ? 89.379  102.795 149.554 1.00 155.68 ? 360 TYR R CD2 1 
ATOM 8540 C CE1 . TYR E 5 413 ? 88.315  100.391 148.718 1.00 156.40 ? 360 TYR R CE1 1 
ATOM 8541 C CE2 . TYR E 5 413 ? 88.341  102.219 150.262 1.00 156.76 ? 360 TYR R CE2 1 
ATOM 8542 C CZ  . TYR E 5 413 ? 87.813  101.018 149.839 1.00 157.76 ? 360 TYR R CZ  1 
ATOM 8543 O OH  . TYR E 5 413 ? 86.779  100.440 150.540 1.00 156.85 ? 360 TYR R OH  1 
ATOM 8544 N N   . LEU E 5 414 ? 94.055  102.984 146.673 1.00 153.38 ? 361 LEU R N   1 
ATOM 8545 C CA  . LEU E 5 414 ? 95.111  103.650 145.915 1.00 153.09 ? 361 LEU R CA  1 
ATOM 8546 C C   . LEU E 5 414 ? 95.774  102.692 144.933 1.00 151.16 ? 361 LEU R C   1 
ATOM 8547 O O   . LEU E 5 414 ? 96.116  103.083 143.810 1.00 150.26 ? 361 LEU R O   1 
ATOM 8548 C CB  . LEU E 5 414 ? 96.147  104.246 146.868 1.00 152.36 ? 361 LEU R CB  1 
ATOM 8549 C CG  . LEU E 5 414 ? 95.673  105.407 147.745 1.00 153.17 ? 361 LEU R CG  1 
ATOM 8550 C CD1 . LEU E 5 414 ? 96.801  105.904 148.637 1.00 152.18 ? 361 LEU R CD1 1 
ATOM 8551 C CD2 . LEU E 5 414 ? 95.118  106.537 146.891 1.00 152.07 ? 361 LEU R CD2 1 
ATOM 8552 N N   . TYR E 5 415 ? 95.974  101.436 145.342 1.00 139.09 ? 362 TYR R N   1 
ATOM 8553 C CA  . TYR E 5 415 ? 96.609  100.459 144.463 1.00 139.14 ? 362 TYR R CA  1 
ATOM 8554 C C   . TYR E 5 415 ? 95.755  100.181 143.233 1.00 138.44 ? 362 TYR R C   1 
ATOM 8555 O O   . TYR E 5 415 ? 96.276  100.080 142.116 1.00 138.97 ? 362 TYR R O   1 
ATOM 8556 C CB  . TYR E 5 415 ? 96.883  99.166  145.230 1.00 138.10 ? 362 TYR R CB  1 
ATOM 8557 C CG  . TYR E 5 415 ? 97.818  98.215  144.518 1.00 139.09 ? 362 TYR R CG  1 
ATOM 8558 C CD1 . TYR E 5 415 ? 99.195  98.367  144.609 1.00 138.44 ? 362 TYR R CD1 1 
ATOM 8559 C CD2 . TYR E 5 415 ? 97.324  97.163  143.758 1.00 137.77 ? 362 TYR R CD2 1 
ATOM 8560 C CE1 . TYR E 5 415 ? 100.054 97.499  143.961 1.00 137.04 ? 362 TYR R CE1 1 
ATOM 8561 C CE2 . TYR E 5 415 ? 98.175  96.290  143.107 1.00 137.87 ? 362 TYR R CE2 1 
ATOM 8562 C CZ  . TYR E 5 415 ? 99.538  96.463  143.212 1.00 137.35 ? 362 TYR R CZ  1 
ATOM 8563 O OH  . TYR E 5 415 ? 100.390 95.597  142.565 1.00 137.16 ? 362 TYR R OH  1 
ATOM 8564 N N   . ASN E 5 416 ? 94.439  100.051 143.416 1.00 141.57 ? 363 ASN R N   1 
ATOM 8565 C CA  . ASN E 5 416 ? 93.559  99.804  142.279 1.00 142.81 ? 363 ASN R CA  1 
ATOM 8566 C C   . ASN E 5 416 ? 93.442  101.029 141.381 1.00 140.23 ? 363 ASN R C   1 
ATOM 8567 O O   . ASN E 5 416 ? 93.277  100.890 140.163 1.00 139.66 ? 363 ASN R O   1 
ATOM 8568 C CB  . ASN E 5 416 ? 92.179  99.365  142.770 1.00 144.87 ? 363 ASN R CB  1 
ATOM 8569 C CG  . ASN E 5 416 ? 92.212  98.024  143.478 1.00 145.54 ? 363 ASN R CG  1 
ATOM 8570 O OD1 . ASN E 5 416 ? 92.113  96.972  142.847 1.00 144.69 ? 363 ASN R OD1 1 
ATOM 8571 N ND2 . ASN E 5 416 ? 92.352  98.056  144.798 1.00 144.49 ? 363 ASN R ND2 1 
ATOM 8572 N N   . ALA E 5 417 ? 93.514  102.230 141.959 1.00 125.90 ? 364 ALA R N   1 
ATOM 8573 C CA  . ALA E 5 417 ? 93.561  103.441 141.146 1.00 126.41 ? 364 ALA R CA  1 
ATOM 8574 C C   . ALA E 5 417 ? 94.829  103.494 140.302 1.00 126.16 ? 364 ALA R C   1 
ATOM 8575 O O   . ALA E 5 417 ? 94.791  103.906 139.137 1.00 125.01 ? 364 ALA R O   1 
ATOM 8576 C CB  . ALA E 5 417 ? 93.457  104.677 142.039 1.00 126.55 ? 364 ALA R CB  1 
ATOM 8577 N N   . ALA E 5 418 ? 95.964  103.088 140.877 1.00 120.34 ? 365 ALA R N   1 
ATOM 8578 C CA  . ALA E 5 418 ? 97.216  103.091 140.126 1.00 119.31 ? 365 ALA R CA  1 
ATOM 8579 C C   . ALA E 5 418 ? 97.188  102.075 138.990 1.00 120.15 ? 365 ALA R C   1 
ATOM 8580 O O   . ALA E 5 418 ? 97.751  102.323 137.917 1.00 120.51 ? 365 ALA R O   1 
ATOM 8581 C CB  . ALA E 5 418 ? 98.391  102.817 141.064 1.00 117.95 ? 365 ALA R CB  1 
ATOM 8582 N N   . ILE E 5 419 ? 96.556  100.919 139.212 1.00 119.49 ? 366 ILE R N   1 
ATOM 8583 C CA  . ILE E 5 419 ? 96.411  99.932  138.145 1.00 117.86 ? 366 ILE R CA  1 
ATOM 8584 C C   . ILE E 5 419 ? 95.662  100.533 136.962 1.00 114.96 ? 366 ILE R C   1 
ATOM 8585 O O   . ILE E 5 419 ? 96.030  100.319 135.800 1.00 113.96 ? 366 ILE R O   1 
ATOM 8586 C CB  . ILE E 5 419 ? 95.711  98.668  138.678 1.00 121.33 ? 366 ILE R CB  1 
ATOM 8587 C CG1 . ILE E 5 419 ? 96.620  97.929  139.661 1.00 120.95 ? 366 ILE R CG1 1 
ATOM 8588 C CG2 . ILE E 5 419 ? 95.307  97.748  137.533 1.00 119.88 ? 366 ILE R CG2 1 
ATOM 8589 C CD1 . ILE E 5 419 ? 96.002  96.673  140.235 1.00 119.64 ? 366 ILE R CD1 1 
ATOM 8590 N N   . SER E 5 420 ? 94.605  101.302 137.238 1.00 109.61 ? 367 SER R N   1 
ATOM 8591 C CA  . SER E 5 420 ? 93.843  101.933 136.165 1.00 109.44 ? 367 SER R CA  1 
ATOM 8592 C C   . SER E 5 420 ? 94.698  102.928 135.390 1.00 109.74 ? 367 SER R C   1 
ATOM 8593 O O   . SER E 5 420 ? 94.588  103.028 134.162 1.00 110.81 ? 367 SER R O   1 
ATOM 8594 C CB  . SER E 5 420 ? 92.606  102.623 136.737 1.00 110.46 ? 367 SER R CB  1 
ATOM 8595 O OG  . SER E 5 420 ? 92.968  103.617 137.680 1.00 111.68 ? 367 SER R OG  1 
ATOM 8596 N N   . LEU E 5 421 ? 95.550  103.678 136.093 1.00 100.67 ? 368 LEU R N   1 
ATOM 8597 C CA  . LEU E 5 421 ? 96.407  104.653 135.425 1.00 102.10 ? 368 LEU R CA  1 
ATOM 8598 C C   . LEU E 5 421 ? 97.381  103.973 134.471 1.00 103.69 ? 368 LEU R C   1 
ATOM 8599 O O   . LEU E 5 421 ? 97.685  104.508 133.398 1.00 101.29 ? 368 LEU R O   1 
ATOM 8600 C CB  . LEU E 5 421 ? 97.159  105.486 136.461 1.00 101.48 ? 368 LEU R CB  1 
ATOM 8601 C CG  . LEU E 5 421 ? 96.285  106.308 137.412 1.00 99.79  ? 368 LEU R CG  1 
ATOM 8602 C CD1 . LEU E 5 421 ? 97.142  107.156 138.338 1.00 100.10 ? 368 LEU R CD1 1 
ATOM 8603 C CD2 . LEU E 5 421 ? 95.311  107.176 136.632 1.00 101.00 ? 368 LEU R CD2 1 
ATOM 8604 N N   . GLY E 5 422 ? 97.891  102.799 134.850 1.00 97.84  ? 369 GLY R N   1 
ATOM 8605 C CA  . GLY E 5 422 ? 98.738  102.046 133.938 1.00 93.52  ? 369 GLY R CA  1 
ATOM 8606 C C   . GLY E 5 422 ? 98.019  101.656 132.661 1.00 91.51  ? 369 GLY R C   1 
ATOM 8607 O O   . GLY E 5 422 ? 98.584  101.740 131.568 1.00 85.18  ? 369 GLY R O   1 
ATOM 8608 N N   . TYR E 5 423 ? 96.762  101.220 132.782 1.00 100.25 ? 370 TYR R N   1 
ATOM 8609 C CA  . TYR E 5 423 ? 95.964  100.941 131.593 1.00 98.59  ? 370 TYR R CA  1 
ATOM 8610 C C   . TYR E 5 423 ? 95.618  102.217 130.838 1.00 96.71  ? 370 TYR R C   1 
ATOM 8611 O O   . TYR E 5 423 ? 95.417  102.179 129.619 1.00 99.14  ? 370 TYR R O   1 
ATOM 8612 C CB  . TYR E 5 423 ? 94.688  100.190 131.977 1.00 97.13  ? 370 TYR R CB  1 
ATOM 8613 C CG  . TYR E 5 423 ? 94.908  98.733  132.321 1.00 95.87  ? 370 TYR R CG  1 
ATOM 8614 C CD1 . TYR E 5 423 ? 94.987  97.769  131.326 1.00 93.66  ? 370 TYR R CD1 1 
ATOM 8615 C CD2 . TYR E 5 423 ? 95.034  98.321  133.640 1.00 98.38  ? 370 TYR R CD2 1 
ATOM 8616 C CE1 . TYR E 5 423 ? 95.189  96.438  131.634 1.00 94.35  ? 370 TYR R CE1 1 
ATOM 8617 C CE2 . TYR E 5 423 ? 95.234  96.991  133.958 1.00 96.60  ? 370 TYR R CE2 1 
ATOM 8618 C CZ  . TYR E 5 423 ? 95.311  96.054  132.951 1.00 94.92  ? 370 TYR R CZ  1 
ATOM 8619 O OH  . TYR E 5 423 ? 95.511  94.729  133.262 1.00 97.79  ? 370 TYR R OH  1 
ATOM 8620 N N   . ALA E 5 424 ? 95.543  103.350 131.539 1.00 86.22  ? 371 ALA R N   1 
ATOM 8621 C CA  . ALA E 5 424 ? 95.275  104.619 130.875 1.00 88.62  ? 371 ALA R CA  1 
ATOM 8622 C C   . ALA E 5 424 ? 96.431  105.076 129.997 1.00 91.25  ? 371 ALA R C   1 
ATOM 8623 O O   . ALA E 5 424 ? 96.225  105.914 129.113 1.00 89.73  ? 371 ALA R O   1 
ATOM 8624 C CB  . ALA E 5 424 ? 94.953  105.696 131.912 1.00 89.58  ? 371 ALA R CB  1 
ATOM 8625 N N   . ASN E 5 425 ? 97.640  104.555 130.224 1.00 89.43  ? 372 ASN R N   1 
ATOM 8626 C CA  . ASN E 5 425 ? 98.760  104.887 129.350 1.00 88.53  ? 372 ASN R CA  1 
ATOM 8627 C C   . ASN E 5 425 ? 98.515  104.397 127.929 1.00 87.97  ? 372 ASN R C   1 
ATOM 8628 O O   . ASN E 5 425 ? 98.812  105.104 126.959 1.00 89.45  ? 372 ASN R O   1 
ATOM 8629 C CB  . ASN E 5 425 ? 100.053 104.292 129.905 1.00 86.39  ? 372 ASN R CB  1 
ATOM 8630 C CG  . ASN E 5 425 ? 101.191 104.336 128.904 1.00 84.87  ? 372 ASN R CG  1 
ATOM 8631 O OD1 . ASN E 5 425 ? 101.442 103.365 128.188 1.00 82.68  ? 372 ASN R OD1 1 
ATOM 8632 N ND2 . ASN E 5 425 ? 101.884 105.467 128.845 1.00 87.54  ? 372 ASN R ND2 1 
ATOM 8633 N N   . SER E 5 426 ? 97.967  103.189 127.787 1.00 85.07  ? 373 SER R N   1 
ATOM 8634 C CA  . SER E 5 426 ? 97.618  102.674 126.469 1.00 82.62  ? 373 SER R CA  1 
ATOM 8635 C C   . SER E 5 426 ? 96.395  103.367 125.885 1.00 83.18  ? 373 SER R C   1 
ATOM 8636 O O   . SER E 5 426 ? 96.157  103.263 124.677 1.00 82.22  ? 373 SER R O   1 
ATOM 8637 C CB  . SER E 5 426 ? 97.380  101.166 126.541 1.00 84.14  ? 373 SER R CB  1 
ATOM 8638 O OG  . SER E 5 426 ? 98.547  100.488 126.972 1.00 85.26  ? 373 SER R OG  1 
ATOM 8639 N N   . CYS E 5 427 ? 95.615  104.064 126.713 1.00 95.43  ? 374 CYS R N   1 
ATOM 8640 C CA  . CYS E 5 427 ? 94.485  104.833 126.208 1.00 97.51  ? 374 CYS R CA  1 
ATOM 8641 C C   . CYS E 5 427 ? 94.896  106.219 125.727 1.00 102.21 ? 374 CYS R C   1 
ATOM 8642 O O   . CYS E 5 427 ? 94.262  106.767 124.819 1.00 103.41 ? 374 CYS R O   1 
ATOM 8643 C CB  . CYS E 5 427 ? 93.411  104.953 127.291 1.00 101.00 ? 374 CYS R CB  1 
ATOM 8644 S SG  . CYS E 5 427 ? 91.974  105.950 126.835 1.00 106.94 ? 374 CYS R SG  1 
ATOM 8645 N N   . LEU E 5 428 ? 95.950  106.793 126.305 1.00 96.85  ? 375 LEU R N   1 
ATOM 8646 C CA  . LEU E 5 428 ? 96.359  108.148 125.958 1.00 94.70  ? 375 LEU R CA  1 
ATOM 8647 C C   . LEU E 5 428 ? 97.413  108.201 124.861 1.00 92.34  ? 375 LEU R C   1 
ATOM 8648 O O   . LEU E 5 428 ? 97.553  109.244 124.211 1.00 91.81  ? 375 LEU R O   1 
ATOM 8649 C CB  . LEU E 5 428 ? 96.887  108.874 127.199 1.00 90.62  ? 375 LEU R CB  1 
ATOM 8650 C CG  . LEU E 5 428 ? 95.872  109.127 128.315 1.00 93.47  ? 375 LEU R CG  1 
ATOM 8651 C CD1 . LEU E 5 428 ? 96.517  109.888 129.461 1.00 94.25  ? 375 LEU R CD1 1 
ATOM 8652 C CD2 . LEU E 5 428 ? 94.666  109.880 127.779 1.00 93.29  ? 375 LEU R CD2 1 
ATOM 8653 N N   . ASN E 5 429 ? 98.151  107.114 124.637 1.00 86.83  ? 376 ASN R N   1 
ATOM 8654 C CA  . ASN E 5 429 ? 99.135  107.096 123.556 1.00 84.53  ? 376 ASN R CA  1 
ATOM 8655 C C   . ASN E 5 429 ? 98.527  107.350 122.181 1.00 83.89  ? 376 ASN R C   1 
ATOM 8656 O O   . ASN E 5 429 ? 99.077  108.182 121.438 1.00 92.08  ? 376 ASN R O   1 
ATOM 8657 C CB  . ASN E 5 429 ? 99.911  105.775 123.588 1.00 85.86  ? 376 ASN R CB  1 
ATOM 8658 C CG  . ASN E 5 429 ? 100.850 105.680 124.774 1.00 89.68  ? 376 ASN R CG  1 
ATOM 8659 O OD1 . ASN E 5 429 ? 101.363 106.690 125.257 1.00 87.65  ? 376 ASN R OD1 1 
ATOM 8660 N ND2 . ASN E 5 429 ? 101.082 104.462 125.249 1.00 91.42  ? 376 ASN R ND2 1 
ATOM 8661 N N   . PRO E 5 430 ? 97.438  106.687 121.764 1.00 79.05  ? 377 PRO R N   1 
ATOM 8662 C CA  . PRO E 5 430 ? 96.900  106.978 120.422 1.00 81.13  ? 377 PRO R CA  1 
ATOM 8663 C C   . PRO E 5 430 ? 96.450  108.419 120.242 1.00 87.61  ? 377 PRO R C   1 
ATOM 8664 O O   . PRO E 5 430 ? 96.625  108.984 119.155 1.00 89.08  ? 377 PRO R O   1 
ATOM 8665 C CB  . PRO E 5 430 ? 95.729  105.993 120.296 1.00 81.52  ? 377 PRO R CB  1 
ATOM 8666 C CG  . PRO E 5 430 ? 95.353  105.669 121.698 1.00 86.96  ? 377 PRO R CG  1 
ATOM 8667 C CD  . PRO E 5 430 ? 96.647  105.645 122.444 1.00 84.02  ? 377 PRO R CD  1 
ATOM 8668 N N   . PHE E 5 431 ? 95.878  109.035 121.279 1.00 87.87  ? 378 PHE R N   1 
ATOM 8669 C CA  . PHE E 5 431 ? 95.355  110.390 121.141 1.00 86.62  ? 378 PHE R CA  1 
ATOM 8670 C C   . PHE E 5 431 ? 96.459  111.441 121.128 1.00 85.46  ? 378 PHE R C   1 
ATOM 8671 O O   . PHE E 5 431 ? 96.272  112.517 120.550 1.00 86.70  ? 378 PHE R O   1 
ATOM 8672 C CB  . PHE E 5 431 ? 94.360  110.688 122.263 1.00 85.83  ? 378 PHE R CB  1 
ATOM 8673 C CG  . PHE E 5 431 ? 93.079  109.912 122.155 1.00 87.88  ? 378 PHE R CG  1 
ATOM 8674 C CD1 . PHE E 5 431 ? 92.131  110.246 121.202 1.00 85.43  ? 378 PHE R CD1 1 
ATOM 8675 C CD2 . PHE E 5 431 ? 92.821  108.852 123.006 1.00 88.75  ? 378 PHE R CD2 1 
ATOM 8676 C CE1 . PHE E 5 431 ? 90.951  109.535 121.099 1.00 86.30  ? 378 PHE R CE1 1 
ATOM 8677 C CE2 . PHE E 5 431 ? 91.642  108.138 122.909 1.00 89.14  ? 378 PHE R CE2 1 
ATOM 8678 C CZ  . PHE E 5 431 ? 90.706  108.480 121.954 1.00 87.31  ? 378 PHE R CZ  1 
ATOM 8679 N N   . VAL E 5 432 ? 97.602  111.157 121.755 1.00 70.34  ? 379 VAL R N   1 
ATOM 8680 C CA  . VAL E 5 432 ? 98.746  112.061 121.658 1.00 69.74  ? 379 VAL R CA  1 
ATOM 8681 C C   . VAL E 5 432 ? 99.196  112.193 120.209 1.00 72.69  ? 379 VAL R C   1 
ATOM 8682 O O   . VAL E 5 432 ? 99.555  113.284 119.748 1.00 75.41  ? 379 VAL R O   1 
ATOM 8683 C CB  . VAL E 5 432 ? 99.888  111.576 122.570 1.00 66.79  ? 379 VAL R CB  1 
ATOM 8684 C CG1 . VAL E 5 432 ? 101.168 112.328 122.265 1.00 69.42  ? 379 VAL R CG1 1 
ATOM 8685 C CG2 . VAL E 5 432 ? 99.512  111.757 124.031 1.00 74.11  ? 379 VAL R CG2 1 
ATOM 8686 N N   . TYR E 5 433 ? 99.164  111.088 119.461 1.00 64.67  ? 380 TYR R N   1 
ATOM 8687 C CA  . TYR E 5 433 ? 99.489  111.142 118.040 1.00 60.95  ? 380 TYR R CA  1 
ATOM 8688 C C   . TYR E 5 433 ? 98.360  111.766 117.228 1.00 68.38  ? 380 TYR R C   1 
ATOM 8689 O O   . TYR E 5 433 ? 98.619  112.433 116.221 1.00 71.34  ? 380 TYR R O   1 
ATOM 8690 C CB  . TYR E 5 433 ? 99.801  109.735 117.530 1.00 59.89  ? 380 TYR R CB  1 
ATOM 8691 C CG  . TYR E 5 433 ? 100.570 109.689 116.229 1.00 63.87  ? 380 TYR R CG  1 
ATOM 8692 C CD1 . TYR E 5 433 ? 101.955 109.790 116.216 1.00 65.32  ? 380 TYR R CD1 1 
ATOM 8693 C CD2 . TYR E 5 433 ? 99.914  109.528 115.017 1.00 66.44  ? 380 TYR R CD2 1 
ATOM 8694 C CE1 . TYR E 5 433 ? 102.664 109.740 115.030 1.00 68.88  ? 380 TYR R CE1 1 
ATOM 8695 C CE2 . TYR E 5 433 ? 100.614 109.478 113.826 1.00 67.60  ? 380 TYR R CE2 1 
ATOM 8696 C CZ  . TYR E 5 433 ? 101.989 109.584 113.838 1.00 69.75  ? 380 TYR R CZ  1 
ATOM 8697 O OH  . TYR E 5 433 ? 102.691 109.534 112.655 1.00 65.08  ? 380 TYR R OH  1 
ATOM 8698 N N   . ILE E 5 434 ? 97.109  111.560 117.645 1.00 85.29  ? 381 ILE R N   1 
ATOM 8699 C CA  . ILE E 5 434 ? 95.975  112.125 116.920 1.00 84.61  ? 381 ILE R CA  1 
ATOM 8700 C C   . ILE E 5 434 ? 95.922  113.640 117.084 1.00 86.68  ? 381 ILE R C   1 
ATOM 8701 O O   . ILE E 5 434 ? 95.652  114.373 116.125 1.00 90.69  ? 381 ILE R O   1 
ATOM 8702 C CB  . ILE E 5 434 ? 94.665  111.458 117.381 1.00 82.22  ? 381 ILE R CB  1 
ATOM 8703 C CG1 . ILE E 5 434 ? 94.588  110.020 116.866 1.00 84.81  ? 381 ILE R CG1 1 
ATOM 8704 C CG2 . ILE E 5 434 ? 93.457  112.254 116.907 1.00 87.39  ? 381 ILE R CG2 1 
ATOM 8705 C CD1 . ILE E 5 434 ? 93.308  109.304 117.240 1.00 88.05  ? 381 ILE R CD1 1 
ATOM 8706 N N   . VAL E 5 435 ? 96.195  114.136 118.287 1.00 81.13  ? 382 VAL R N   1 
ATOM 8707 C CA  . VAL E 5 435 ? 95.998  115.552 118.592 1.00 79.51  ? 382 VAL R CA  1 
ATOM 8708 C C   . VAL E 5 435 ? 97.211  116.387 118.203 1.00 82.98  ? 382 VAL R C   1 
ATOM 8709 O O   . VAL E 5 435 ? 97.074  117.444 117.581 1.00 85.80  ? 382 VAL R O   1 
ATOM 8710 C CB  . VAL E 5 435 ? 95.651  115.728 120.086 1.00 78.20  ? 382 VAL R CB  1 
ATOM 8711 C CG1 . VAL E 5 435 ? 95.640  117.202 120.457 1.00 78.73  ? 382 VAL R CG1 1 
ATOM 8712 C CG2 . VAL E 5 435 ? 94.304  115.094 120.395 1.00 81.00  ? 382 VAL R CG2 1 
ATOM 8713 N N   . LEU E 5 436 ? 98.413  115.938 118.549 1.00 74.66  ? 383 LEU R N   1 
ATOM 8714 C CA  . LEU E 5 436 ? 99.605  116.758 118.380 1.00 71.77  ? 383 LEU R CA  1 
ATOM 8715 C C   . LEU E 5 436 ? 100.207 116.666 116.984 1.00 75.01  ? 383 LEU R C   1 
ATOM 8716 O O   . LEU E 5 436 ? 101.220 117.321 116.720 1.00 73.79  ? 383 LEU R O   1 
ATOM 8717 C CB  . LEU E 5 436 ? 100.656 116.371 119.426 1.00 61.41  ? 383 LEU R CB  1 
ATOM 8718 C CG  . LEU E 5 436 ? 100.217 116.575 120.879 1.00 67.94  ? 383 LEU R CG  1 
ATOM 8719 C CD1 . LEU E 5 436 ? 101.257 116.048 121.850 1.00 72.02  ? 383 LEU R CD1 1 
ATOM 8720 C CD2 . LEU E 5 436 ? 99.938  118.047 121.145 1.00 67.99  ? 383 LEU R CD2 1 
ATOM 8721 N N   . CYS E 5 437 ? 99.620  115.878 116.088 1.00 79.90  ? 384 CYS R N   1 
ATOM 8722 C CA  . CYS E 5 437 ? 100.028 115.827 114.686 1.00 79.65  ? 384 CYS R CA  1 
ATOM 8723 C C   . CYS E 5 437 ? 98.937  116.503 113.861 1.00 80.94  ? 384 CYS R C   1 
ATOM 8724 O O   . CYS E 5 437 ? 97.892  115.904 113.592 1.00 78.81  ? 384 CYS R O   1 
ATOM 8725 C CB  . CYS E 5 437 ? 100.271 114.393 114.228 1.00 79.07  ? 384 CYS R CB  1 
ATOM 8726 S SG  . CYS E 5 437 ? 101.083 114.271 112.617 1.00 74.02  ? 384 CYS R SG  1 
ATOM 8727 N N   . GLU E 5 438 ? 99.179  117.758 113.473 1.00 97.57  ? 385 GLU R N   1 
ATOM 8728 C CA  . GLU E 5 438 ? 98.250  118.451 112.585 1.00 101.62 ? 385 GLU R CA  1 
ATOM 8729 C C   . GLU E 5 438 ? 98.075  117.703 111.268 1.00 103.67 ? 385 GLU R C   1 
ATOM 8730 O O   . GLU E 5 438 ? 96.962  117.628 110.733 1.00 104.87 ? 385 GLU R O   1 
ATOM 8731 C CB  . GLU E 5 438 ? 98.735  119.878 112.331 1.00 97.78  ? 385 GLU R CB  1 
ATOM 8732 N N   . THR E 5 439 ? 99.164  117.152 110.726 1.00 98.11  ? 386 THR R N   1 
ATOM 8733 C CA  . THR E 5 439 ? 99.077  116.421 109.466 1.00 96.92  ? 386 THR R CA  1 
ATOM 8734 C C   . THR E 5 439 ? 98.200  115.182 109.601 1.00 94.74  ? 386 THR R C   1 
ATOM 8735 O O   . THR E 5 439 ? 97.387  114.887 108.717 1.00 92.87  ? 386 THR R O   1 
ATOM 8736 C CB  . THR E 5 439 ? 100.475 116.031 108.985 1.00 95.61  ? 386 THR R CB  1 
ATOM 8737 O OG1 . THR E 5 439 ? 101.295 117.203 108.890 1.00 94.79  ? 386 THR R OG1 1 
ATOM 8738 C CG2 . THR E 5 439 ? 100.404 115.357 107.622 1.00 95.33  ? 386 THR R CG2 1 
ATOM 8739 N N   . PHE E 5 440 ? 98.347  114.446 110.705 1.00 87.87  ? 387 PHE R N   1 
ATOM 8740 C CA  . PHE E 5 440 ? 97.525  113.259 110.914 1.00 87.88  ? 387 PHE R CA  1 
ATOM 8741 C C   . PHE E 5 440 ? 96.070  113.633 111.169 1.00 88.50  ? 387 PHE R C   1 
ATOM 8742 O O   . PHE E 5 440 ? 95.156  112.931 110.721 1.00 90.37  ? 387 PHE R O   1 
ATOM 8743 C CB  . PHE E 5 440 ? 98.083  112.438 112.077 1.00 90.06  ? 387 PHE R CB  1 
ATOM 8744 C CG  . PHE E 5 440 ? 97.527  111.047 112.159 1.00 88.99  ? 387 PHE R CG  1 
ATOM 8745 C CD1 . PHE E 5 440 ? 98.100  110.018 111.431 1.00 86.72  ? 387 PHE R CD1 1 
ATOM 8746 C CD2 . PHE E 5 440 ? 96.434  110.767 112.961 1.00 87.26  ? 387 PHE R CD2 1 
ATOM 8747 C CE1 . PHE E 5 440 ? 97.595  108.737 111.503 1.00 87.26  ? 387 PHE R CE1 1 
ATOM 8748 C CE2 . PHE E 5 440 ? 95.924  109.487 113.035 1.00 86.43  ? 387 PHE R CE2 1 
ATOM 8749 C CZ  . PHE E 5 440 ? 96.506  108.471 112.306 1.00 85.82  ? 387 PHE R CZ  1 
ATOM 8750 N N   . ARG E 5 441 ? 95.839  114.728 111.897 1.00 91.99  ? 388 ARG R N   1 
ATOM 8751 C CA  . ARG E 5 441 ? 94.474  115.140 112.212 1.00 94.60  ? 388 ARG R CA  1 
ATOM 8752 C C   . ARG E 5 441 ? 93.700  115.499 110.949 1.00 97.42  ? 388 ARG R C   1 
ATOM 8753 O O   . ARG E 5 441 ? 92.517  115.165 110.820 1.00 99.11  ? 388 ARG R O   1 
ATOM 8754 C CB  . ARG E 5 441 ? 94.493  116.319 113.185 1.00 95.96  ? 388 ARG R CB  1 
ATOM 8755 C CG  . ARG E 5 441 ? 93.169  116.560 113.892 1.00 96.74  ? 388 ARG R CG  1 
ATOM 8756 C CD  . ARG E 5 441 ? 93.331  117.519 115.059 1.00 96.33  ? 388 ARG R CD  1 
ATOM 8757 N NE  . ARG E 5 441 ? 94.231  118.620 114.737 1.00 97.07  ? 388 ARG R NE  1 
ATOM 8758 C CZ  . ARG E 5 441 ? 94.598  119.563 115.595 1.00 97.64  ? 388 ARG R CZ  1 
ATOM 8759 N NH1 . ARG E 5 441 ? 94.159  119.571 116.843 1.00 101.62 ? 388 ARG R NH1 1 
ATOM 8760 N NH2 . ARG E 5 441 ? 95.424  120.523 115.189 1.00 93.53  ? 388 ARG R NH2 1 
ATOM 8761 N N   . LYS E 5 442 ? 94.355  116.181 110.007 1.00 107.19 ? 389 LYS R N   1 
ATOM 8762 C CA  . LYS E 5 442 ? 93.680  116.606 108.784 1.00 107.25 ? 389 LYS R CA  1 
ATOM 8763 C C   . LYS E 5 442 ? 93.324  115.416 107.900 1.00 106.41 ? 389 LYS R C   1 
ATOM 8764 O O   . LYS E 5 442 ? 92.228  115.368 107.328 1.00 105.67 ? 389 LYS R O   1 
ATOM 8765 C CB  . LYS E 5 442 ? 94.557  117.598 108.020 1.00 104.77 ? 389 LYS R CB  1 
ATOM 8766 N N   . ARG E 5 443 ? 94.238  114.452 107.767 1.00 105.46 ? 390 ARG R N   1 
ATOM 8767 C CA  . ARG E 5 443 ? 93.967  113.294 106.922 1.00 103.56 ? 390 ARG R CA  1 
ATOM 8768 C C   . ARG E 5 443 ? 92.841  112.435 107.484 1.00 105.62 ? 390 ARG R C   1 
ATOM 8769 O O   . ARG E 5 443 ? 92.071  111.849 106.716 1.00 108.47 ? 390 ARG R O   1 
ATOM 8770 C CB  . ARG E 5 443 ? 95.237  112.459 106.753 1.00 104.65 ? 390 ARG R CB  1 
ATOM 8771 N N   . LEU E 5 444 ? 92.737  112.337 108.812 1.00 107.32 ? 391 LEU R N   1 
ATOM 8772 C CA  . LEU E 5 444 ? 91.655  111.562 109.410 1.00 109.08 ? 391 LEU R CA  1 
ATOM 8773 C C   . LEU E 5 444 ? 90.296  112.169 109.083 1.00 109.25 ? 391 LEU R C   1 
ATOM 8774 O O   . LEU E 5 444 ? 89.327  111.444 108.830 1.00 107.55 ? 391 LEU R O   1 
ATOM 8775 C CB  . LEU E 5 444 ? 91.851  111.467 110.923 1.00 107.82 ? 391 LEU R CB  1 
ATOM 8776 C CG  . LEU E 5 444 ? 90.789  110.677 111.691 1.00 109.65 ? 391 LEU R CG  1 
ATOM 8777 C CD1 . LEU E 5 444 ? 90.699  109.252 111.167 1.00 109.50 ? 391 LEU R CD1 1 
ATOM 8778 C CD2 . LEU E 5 444 ? 91.080  110.689 113.184 1.00 107.30 ? 391 LEU R CD2 1 
ATOM 8779 N N   . VAL E 5 445 ? 90.205  113.501 109.089 1.00 114.78 ? 392 VAL R N   1 
ATOM 8780 C CA  . VAL E 5 445 ? 88.945  114.165 108.766 1.00 116.14 ? 392 VAL R CA  1 
ATOM 8781 C C   . VAL E 5 445 ? 88.582  113.939 107.303 1.00 118.02 ? 392 VAL R C   1 
ATOM 8782 O O   . VAL E 5 445 ? 87.404  113.792 106.957 1.00 119.38 ? 392 VAL R O   1 
ATOM 8783 C CB  . VAL E 5 445 ? 89.030  115.665 109.108 1.00 117.23 ? 392 VAL R CB  1 
ATOM 8784 C CG1 . VAL E 5 445 ? 87.725  116.368 108.766 1.00 117.54 ? 392 VAL R CG1 1 
ATOM 8785 C CG2 . VAL E 5 445 ? 89.364  115.853 110.579 1.00 116.43 ? 392 VAL R CG2 1 
ATOM 8786 N N   . LEU E 5 446 ? 89.587  113.908 106.423 1.00 121.72 ? 393 LEU R N   1 
ATOM 8787 C CA  . LEU E 5 446 ? 89.327  113.680 105.004 1.00 120.69 ? 393 LEU R CA  1 
ATOM 8788 C C   . LEU E 5 446 ? 88.682  112.320 104.771 1.00 119.46 ? 393 LEU R C   1 
ATOM 8789 O O   . LEU E 5 446 ? 87.760  112.193 103.957 1.00 117.50 ? 393 LEU R O   1 
ATOM 8790 C CB  . LEU E 5 446 ? 90.626  113.802 104.208 1.00 116.39 ? 393 LEU R CB  1 
ATOM 8791 N N   . SER E 5 447 ? 89.159  111.288 105.472 1.00 119.65 ? 394 SER R N   1 
ATOM 8792 C CA  . SER E 5 447 ? 88.570  109.961 105.344 1.00 118.45 ? 394 SER R CA  1 
ATOM 8793 C C   . SER E 5 447 ? 87.133  109.913 105.849 1.00 119.29 ? 394 SER R C   1 
ATOM 8794 O O   . SER E 5 447 ? 86.374  109.030 105.436 1.00 118.16 ? 394 SER R O   1 
ATOM 8795 C CB  . SER E 5 447 ? 89.418  108.934 106.095 1.00 117.99 ? 394 SER R CB  1 
ATOM 8796 O OG  . SER E 5 447 ? 90.741  108.895 105.588 1.00 119.02 ? 394 SER R OG  1 
ATOM 8797 N N   . VAL E 5 448 ? 86.745  110.834 106.725 1.00 123.06 ? 395 VAL R N   1 
ATOM 8798 C CA  . VAL E 5 448 ? 85.382  110.882 107.236 1.00 123.04 ? 395 VAL R CA  1 
ATOM 8799 C C   . VAL E 5 448 ? 84.557  111.889 106.443 1.00 123.63 ? 395 VAL R C   1 
ATOM 8800 O O   . VAL E 5 448 ? 84.875  112.200 105.296 1.00 122.95 ? 395 VAL R O   1 
ATOM 8801 C CB  . VAL E 5 448 ? 85.359  111.223 108.735 1.00 121.00 ? 395 VAL R CB  1 
ATOM 8802 C CG1 . VAL E 5 448 ? 83.927  111.273 109.247 1.00 122.46 ? 395 VAL R CG1 1 
ATOM 8803 C CG2 . VAL E 5 448 ? 86.179  110.212 109.522 1.00 121.08 ? 395 VAL R CG2 1 
# 
