data_8WWH
# 
_entry.id   8WWH 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.398 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8WWH         pdb_00008wwh 10.2210/pdb8wwh/pdb 
WWPDB D_1300040703 ?            ?                   
EMDB  EMD-37888    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2024-11-13 
2 'Structure model' 1 1 2024-11-27 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Data collection' 
# 
_pdbx_audit_revision_category.ordinal             1 
_pdbx_audit_revision_category.revision_ordinal    2 
_pdbx_audit_revision_category.data_content_type   'Structure model' 
_pdbx_audit_revision_category.category            em_admin 
# 
_pdbx_audit_revision_item.ordinal             1 
_pdbx_audit_revision_item.revision_ordinal    2 
_pdbx_audit_revision_item.data_content_type   'Structure model' 
_pdbx_audit_revision_item.item                '_em_admin.last_update' 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8WWH 
_pdbx_database_status.recvd_initial_deposition_date   2023-10-25 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'MCHR1-Gi complex,S1 state' 
_pdbx_database_related.db_id          EMD-37888 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              wgong@ustc.edu.cn 
_pdbx_contact_author.name_first         Weimin 
_pdbx_contact_author.name_last          Gong 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-6723-1298 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Gong, W.' 1 0000-0002-6723-1298 
'Ye, X.'   2 0009-0008-6388-0873 
'Liu, G.'  3 0009-0005-7555-0167 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Structural insights into ligand recognition and activation of melanin-concentrating hormone receptor MCHR1' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Gong, W.' 1 0000-0002-6723-1298 
primary 'Ye, X.'   2 0009-0008-6388-0873 
primary 'Liu, G.'  3 0009-0005-7555-0167 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'Guanine nucleotide-binding protein G(i) subunit alpha-1'                    40414.047 1 ? ? ? ? 
2 polymer man 'Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1'           40845.559 1 ? ? ? ? 
3 polymer man 'Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2'          7861.143  1 ? ? ? ? 
4 polymer man 'Antibody fragment ScFv16'                                                   27374.430 1 ? ? ? ? 
5 polymer man 'Fusion protein 1,Melanin-concentrating hormone receptor 1,Fusion protein 2' 68207.039 1 ? ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'Adenylate cyclase-inhibiting G alpha protein'                                                                          
2 'Transducin beta chain 1'                                                                                               
3 'G gamma-I'                                                                                                             
5 'MCH receptor 1,MCH-R1,MCHR-1,G-protein coupled receptor 24,MCH-1R,MCH1R,MCHR,SLC-1,Somatostatin receptor-like protein' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKNTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQS
IIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLD
RIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGAQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM
NRMHASMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIY
THFTCSTDTKNVQFVFDAVTDVIIKNNLKDCGLF
;
;MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKNTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQS
IIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLD
RIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGAQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM
NRMHASMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIY
THFTCSTDTKNVQFVFDAVTDVIIKNNLKDCGLF
;
A ? 
2 'polypeptide(L)' no no 
;MHHHHHHGSSGSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLL
VSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCR
FLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDIN
AICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAG
HDNRVSCLGVTDDGMAVATGSWDSFLKIWNGSSGGGGSGGGGSSGVSGWRLFKKIS
;
;MHHHHHHGSSGSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLL
VSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCR
FLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDIN
AICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAG
HDNRVSCLGVTDDGMAVATGSWDSFLKIWNGSSGGGGSGGGGSSGVSGWRLFKKIS
;
B ? 
3 'polypeptide(L)' no no MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL 
MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL C ? 
4 'polypeptide(L)' no no 
;DVQLVESGGGLVQPGGSRKLSCSASGFAFSSFGMHWVRQAPEKGLEWVAYISSGSGTIYYADTVKGRFTISRDDPKNTLF
LQMTSLRSEDTAMYYCVRSIYYYGSSPFDFWGQGTTLTVSSGGGGSGGGGSGGGGSDIVMTQATSSVPVTPGESVSISCR
SSKSLLHSNGNTYLYWFLQRPGQSPQLLIYRMSNLASGVPDRFSGSGSGTAFTLTISRLEAEDVGVYYCMQHLEYPLTFG
AGTKLELLEENLYFQ
;
;DVQLVESGGGLVQPGGSRKLSCSASGFAFSSFGMHWVRQAPEKGLEWVAYISSGSGTIYYADTVKGRFTISRDDPKNTLF
LQMTSLRSEDTAMYYCVRSIYYYGSSPFDFWGQGTTLTVSSGGGGSGGGGSGGGGSDIVMTQATSSVPVTPGESVSISCR
SSKSLLHSNGNTYLYWFLQRPGQSPQLLIYRMSNLASGVPDRFSGSGSGTAFTLTISRLEAEDVGVYYCMQHLEYPLTFG
AGTKLELLEENLYFQ
;
E ? 
5 'polypeptide(L)' no no 
;DYKDDDDHHHHHHHHGQPGNGSAFLLAPNGSHAPDHNVTQQRDEENLYFQGVDMSVGAMKKGVGRAVGLGGGSGCQATEE
DPLPNCGACAPGQGGRRWRLPQPAWVEGSSARLWEQATGTGWMDLEASLLPTGPNASNTSDGPDNLTSAGSPPRTGSISY
INIIMPSVFGTICLLGIIGNSTVIFAVVKKSKLHWCNNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTL
ITAMDANSQFTSTYILTAMAIDRYLATVHPISSTKFRKPSVATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRL
PNPDTDLYWFTLYQFFLAFALPFVVITAAYVRILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLT
QLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKHMGSSGGGGSGGGGSSGVFTLEDFVGDWEQT
AAYNLDQVLEQGGVSSLLQNLAVSVTPIQRIVRSGENALKIDIHVIIPYEGLSADQMAQIEEVFKVVYPVDDHHFKVILP
YGTLVIDGVTPNMLNYFGRPYEGIAVFDGKKITVTGTLWNGNKIIDERLITPDGSMLFRVTINS
;
;DYKDDDDHHHHHHHHGQPGNGSAFLLAPNGSHAPDHNVTQQRDEENLYFQGVDMSVGAMKKGVGRAVGLGGGSGCQATEE
DPLPNCGACAPGQGGRRWRLPQPAWVEGSSARLWEQATGTGWMDLEASLLPTGPNASNTSDGPDNLTSAGSPPRTGSISY
INIIMPSVFGTICLLGIIGNSTVIFAVVKKSKLHWCNNVPDIFIINLSVVDLLFLLGMPFMIHQLMGNGVWHFGETMCTL
ITAMDANSQFTSTYILTAMAIDRYLATVHPISSTKFRKPSVATLVICLLWALSFISITPVWLYARLIPFPGGAVGCGIRL
PNPDTDLYWFTLYQFFLAFALPFVVITAAYVRILQRMTSSVAPASQRSIRLRTKRVTRTAIAICLVFFVCWAPYYVLQLT
QLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVKHMGSSGGGGSGGGGSSGVFTLEDFVGDWEQT
AAYNLDQVLEQGGVSSLLQNLAVSVTPIQRIVRSGENALKIDIHVIIPYEGLSADQMAQIEEVFKVVYPVDDHHFKVILP
YGTLVIDGVTPNMLNYFGRPYEGIAVFDGKKITVTGTLWNGNKIIDERLITPDGSMLFRVTINS
;
R ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   GLY n 
1 3   CYS n 
1 4   THR n 
1 5   LEU n 
1 6   SER n 
1 7   ALA n 
1 8   GLU n 
1 9   ASP n 
1 10  LYS n 
1 11  ALA n 
1 12  ALA n 
1 13  VAL n 
1 14  GLU n 
1 15  ARG n 
1 16  SER n 
1 17  LYS n 
1 18  MET n 
1 19  ILE n 
1 20  ASP n 
1 21  ARG n 
1 22  ASN n 
1 23  LEU n 
1 24  ARG n 
1 25  GLU n 
1 26  ASP n 
1 27  GLY n 
1 28  GLU n 
1 29  LYS n 
1 30  ALA n 
1 31  ALA n 
1 32  ARG n 
1 33  GLU n 
1 34  VAL n 
1 35  LYS n 
1 36  LEU n 
1 37  LEU n 
1 38  LEU n 
1 39  LEU n 
1 40  GLY n 
1 41  ALA n 
1 42  GLY n 
1 43  GLU n 
1 44  SER n 
1 45  GLY n 
1 46  LYS n 
1 47  ASN n 
1 48  THR n 
1 49  ILE n 
1 50  VAL n 
1 51  LYS n 
1 52  GLN n 
1 53  MET n 
1 54  LYS n 
1 55  ILE n 
1 56  ILE n 
1 57  HIS n 
1 58  GLU n 
1 59  ALA n 
1 60  GLY n 
1 61  TYR n 
1 62  SER n 
1 63  GLU n 
1 64  GLU n 
1 65  GLU n 
1 66  CYS n 
1 67  LYS n 
1 68  GLN n 
1 69  TYR n 
1 70  LYS n 
1 71  ALA n 
1 72  VAL n 
1 73  VAL n 
1 74  TYR n 
1 75  SER n 
1 76  ASN n 
1 77  THR n 
1 78  ILE n 
1 79  GLN n 
1 80  SER n 
1 81  ILE n 
1 82  ILE n 
1 83  ALA n 
1 84  ILE n 
1 85  ILE n 
1 86  ARG n 
1 87  ALA n 
1 88  MET n 
1 89  GLY n 
1 90  ARG n 
1 91  LEU n 
1 92  LYS n 
1 93  ILE n 
1 94  ASP n 
1 95  PHE n 
1 96  GLY n 
1 97  ASP n 
1 98  SER n 
1 99  ALA n 
1 100 ARG n 
1 101 ALA n 
1 102 ASP n 
1 103 ASP n 
1 104 ALA n 
1 105 ARG n 
1 106 GLN n 
1 107 LEU n 
1 108 PHE n 
1 109 VAL n 
1 110 LEU n 
1 111 ALA n 
1 112 GLY n 
1 113 ALA n 
1 114 ALA n 
1 115 GLU n 
1 116 GLU n 
1 117 GLY n 
1 118 PHE n 
1 119 MET n 
1 120 THR n 
1 121 ALA n 
1 122 GLU n 
1 123 LEU n 
1 124 ALA n 
1 125 GLY n 
1 126 VAL n 
1 127 ILE n 
1 128 LYS n 
1 129 ARG n 
1 130 LEU n 
1 131 TRP n 
1 132 LYS n 
1 133 ASP n 
1 134 SER n 
1 135 GLY n 
1 136 VAL n 
1 137 GLN n 
1 138 ALA n 
1 139 CYS n 
1 140 PHE n 
1 141 ASN n 
1 142 ARG n 
1 143 SER n 
1 144 ARG n 
1 145 GLU n 
1 146 TYR n 
1 147 GLN n 
1 148 LEU n 
1 149 ASN n 
1 150 ASP n 
1 151 SER n 
1 152 ALA n 
1 153 ALA n 
1 154 TYR n 
1 155 TYR n 
1 156 LEU n 
1 157 ASN n 
1 158 ASP n 
1 159 LEU n 
1 160 ASP n 
1 161 ARG n 
1 162 ILE n 
1 163 ALA n 
1 164 GLN n 
1 165 PRO n 
1 166 ASN n 
1 167 TYR n 
1 168 ILE n 
1 169 PRO n 
1 170 THR n 
1 171 GLN n 
1 172 GLN n 
1 173 ASP n 
1 174 VAL n 
1 175 LEU n 
1 176 ARG n 
1 177 THR n 
1 178 ARG n 
1 179 VAL n 
1 180 LYS n 
1 181 THR n 
1 182 THR n 
1 183 GLY n 
1 184 ILE n 
1 185 VAL n 
1 186 GLU n 
1 187 THR n 
1 188 HIS n 
1 189 PHE n 
1 190 THR n 
1 191 PHE n 
1 192 LYS n 
1 193 ASP n 
1 194 LEU n 
1 195 HIS n 
1 196 PHE n 
1 197 LYS n 
1 198 MET n 
1 199 PHE n 
1 200 ASP n 
1 201 VAL n 
1 202 GLY n 
1 203 ALA n 
1 204 GLN n 
1 205 ARG n 
1 206 SER n 
1 207 GLU n 
1 208 ARG n 
1 209 LYS n 
1 210 LYS n 
1 211 TRP n 
1 212 ILE n 
1 213 HIS n 
1 214 CYS n 
1 215 PHE n 
1 216 GLU n 
1 217 GLY n 
1 218 VAL n 
1 219 THR n 
1 220 ALA n 
1 221 ILE n 
1 222 ILE n 
1 223 PHE n 
1 224 CYS n 
1 225 VAL n 
1 226 ALA n 
1 227 LEU n 
1 228 SER n 
1 229 ASP n 
1 230 TYR n 
1 231 ASP n 
1 232 LEU n 
1 233 VAL n 
1 234 LEU n 
1 235 ALA n 
1 236 GLU n 
1 237 ASP n 
1 238 GLU n 
1 239 GLU n 
1 240 MET n 
1 241 ASN n 
1 242 ARG n 
1 243 MET n 
1 244 HIS n 
1 245 ALA n 
1 246 SER n 
1 247 MET n 
1 248 LYS n 
1 249 LEU n 
1 250 PHE n 
1 251 ASP n 
1 252 SER n 
1 253 ILE n 
1 254 CYS n 
1 255 ASN n 
1 256 ASN n 
1 257 LYS n 
1 258 TRP n 
1 259 PHE n 
1 260 THR n 
1 261 ASP n 
1 262 THR n 
1 263 SER n 
1 264 ILE n 
1 265 ILE n 
1 266 LEU n 
1 267 PHE n 
1 268 LEU n 
1 269 ASN n 
1 270 LYS n 
1 271 LYS n 
1 272 ASP n 
1 273 LEU n 
1 274 PHE n 
1 275 GLU n 
1 276 GLU n 
1 277 LYS n 
1 278 ILE n 
1 279 LYS n 
1 280 LYS n 
1 281 SER n 
1 282 PRO n 
1 283 LEU n 
1 284 THR n 
1 285 ILE n 
1 286 CYS n 
1 287 TYR n 
1 288 PRO n 
1 289 GLU n 
1 290 TYR n 
1 291 ALA n 
1 292 GLY n 
1 293 SER n 
1 294 ASN n 
1 295 THR n 
1 296 TYR n 
1 297 GLU n 
1 298 GLU n 
1 299 ALA n 
1 300 ALA n 
1 301 ALA n 
1 302 TYR n 
1 303 ILE n 
1 304 GLN n 
1 305 CYS n 
1 306 GLN n 
1 307 PHE n 
1 308 GLU n 
1 309 ASP n 
1 310 LEU n 
1 311 ASN n 
1 312 LYS n 
1 313 ARG n 
1 314 LYS n 
1 315 ASP n 
1 316 THR n 
1 317 LYS n 
1 318 GLU n 
1 319 ILE n 
1 320 TYR n 
1 321 THR n 
1 322 HIS n 
1 323 PHE n 
1 324 THR n 
1 325 CYS n 
1 326 SER n 
1 327 THR n 
1 328 ASP n 
1 329 THR n 
1 330 LYS n 
1 331 ASN n 
1 332 VAL n 
1 333 GLN n 
1 334 PHE n 
1 335 VAL n 
1 336 PHE n 
1 337 ASP n 
1 338 ALA n 
1 339 VAL n 
1 340 THR n 
1 341 ASP n 
1 342 VAL n 
1 343 ILE n 
1 344 ILE n 
1 345 LYS n 
1 346 ASN n 
1 347 ASN n 
1 348 LEU n 
1 349 LYS n 
1 350 ASP n 
1 351 CYS n 
1 352 GLY n 
1 353 LEU n 
1 354 PHE n 
2 1   MET n 
2 2   HIS n 
2 3   HIS n 
2 4   HIS n 
2 5   HIS n 
2 6   HIS n 
2 7   HIS n 
2 8   GLY n 
2 9   SER n 
2 10  SER n 
2 11  GLY n 
2 12  SER n 
2 13  GLU n 
2 14  LEU n 
2 15  ASP n 
2 16  GLN n 
2 17  LEU n 
2 18  ARG n 
2 19  GLN n 
2 20  GLU n 
2 21  ALA n 
2 22  GLU n 
2 23  GLN n 
2 24  LEU n 
2 25  LYS n 
2 26  ASN n 
2 27  GLN n 
2 28  ILE n 
2 29  ARG n 
2 30  ASP n 
2 31  ALA n 
2 32  ARG n 
2 33  LYS n 
2 34  ALA n 
2 35  CYS n 
2 36  ALA n 
2 37  ASP n 
2 38  ALA n 
2 39  THR n 
2 40  LEU n 
2 41  SER n 
2 42  GLN n 
2 43  ILE n 
2 44  THR n 
2 45  ASN n 
2 46  ASN n 
2 47  ILE n 
2 48  ASP n 
2 49  PRO n 
2 50  VAL n 
2 51  GLY n 
2 52  ARG n 
2 53  ILE n 
2 54  GLN n 
2 55  MET n 
2 56  ARG n 
2 57  THR n 
2 58  ARG n 
2 59  ARG n 
2 60  THR n 
2 61  LEU n 
2 62  ARG n 
2 63  GLY n 
2 64  HIS n 
2 65  LEU n 
2 66  ALA n 
2 67  LYS n 
2 68  ILE n 
2 69  TYR n 
2 70  ALA n 
2 71  MET n 
2 72  HIS n 
2 73  TRP n 
2 74  GLY n 
2 75  THR n 
2 76  ASP n 
2 77  SER n 
2 78  ARG n 
2 79  LEU n 
2 80  LEU n 
2 81  VAL n 
2 82  SER n 
2 83  ALA n 
2 84  SER n 
2 85  GLN n 
2 86  ASP n 
2 87  GLY n 
2 88  LYS n 
2 89  LEU n 
2 90  ILE n 
2 91  ILE n 
2 92  TRP n 
2 93  ASP n 
2 94  SER n 
2 95  TYR n 
2 96  THR n 
2 97  THR n 
2 98  ASN n 
2 99  LYS n 
2 100 VAL n 
2 101 HIS n 
2 102 ALA n 
2 103 ILE n 
2 104 PRO n 
2 105 LEU n 
2 106 ARG n 
2 107 SER n 
2 108 SER n 
2 109 TRP n 
2 110 VAL n 
2 111 MET n 
2 112 THR n 
2 113 CYS n 
2 114 ALA n 
2 115 TYR n 
2 116 ALA n 
2 117 PRO n 
2 118 SER n 
2 119 GLY n 
2 120 ASN n 
2 121 TYR n 
2 122 VAL n 
2 123 ALA n 
2 124 CYS n 
2 125 GLY n 
2 126 GLY n 
2 127 LEU n 
2 128 ASP n 
2 129 ASN n 
2 130 ILE n 
2 131 CYS n 
2 132 SER n 
2 133 ILE n 
2 134 TYR n 
2 135 ASN n 
2 136 LEU n 
2 137 LYS n 
2 138 THR n 
2 139 ARG n 
2 140 GLU n 
2 141 GLY n 
2 142 ASN n 
2 143 VAL n 
2 144 ARG n 
2 145 VAL n 
2 146 SER n 
2 147 ARG n 
2 148 GLU n 
2 149 LEU n 
2 150 ALA n 
2 151 GLY n 
2 152 HIS n 
2 153 THR n 
2 154 GLY n 
2 155 TYR n 
2 156 LEU n 
2 157 SER n 
2 158 CYS n 
2 159 CYS n 
2 160 ARG n 
2 161 PHE n 
2 162 LEU n 
2 163 ASP n 
2 164 ASP n 
2 165 ASN n 
2 166 GLN n 
2 167 ILE n 
2 168 VAL n 
2 169 THR n 
2 170 SER n 
2 171 SER n 
2 172 GLY n 
2 173 ASP n 
2 174 THR n 
2 175 THR n 
2 176 CYS n 
2 177 ALA n 
2 178 LEU n 
2 179 TRP n 
2 180 ASP n 
2 181 ILE n 
2 182 GLU n 
2 183 THR n 
2 184 GLY n 
2 185 GLN n 
2 186 GLN n 
2 187 THR n 
2 188 THR n 
2 189 THR n 
2 190 PHE n 
2 191 THR n 
2 192 GLY n 
2 193 HIS n 
2 194 THR n 
2 195 GLY n 
2 196 ASP n 
2 197 VAL n 
2 198 MET n 
2 199 SER n 
2 200 LEU n 
2 201 SER n 
2 202 LEU n 
2 203 ALA n 
2 204 PRO n 
2 205 ASP n 
2 206 THR n 
2 207 ARG n 
2 208 LEU n 
2 209 PHE n 
2 210 VAL n 
2 211 SER n 
2 212 GLY n 
2 213 ALA n 
2 214 CYS n 
2 215 ASP n 
2 216 ALA n 
2 217 SER n 
2 218 ALA n 
2 219 LYS n 
2 220 LEU n 
2 221 TRP n 
2 222 ASP n 
2 223 VAL n 
2 224 ARG n 
2 225 GLU n 
2 226 GLY n 
2 227 MET n 
2 228 CYS n 
2 229 ARG n 
2 230 GLN n 
2 231 THR n 
2 232 PHE n 
2 233 THR n 
2 234 GLY n 
2 235 HIS n 
2 236 GLU n 
2 237 SER n 
2 238 ASP n 
2 239 ILE n 
2 240 ASN n 
2 241 ALA n 
2 242 ILE n 
2 243 CYS n 
2 244 PHE n 
2 245 PHE n 
2 246 PRO n 
2 247 ASN n 
2 248 GLY n 
2 249 ASN n 
2 250 ALA n 
2 251 PHE n 
2 252 ALA n 
2 253 THR n 
2 254 GLY n 
2 255 SER n 
2 256 ASP n 
2 257 ASP n 
2 258 ALA n 
2 259 THR n 
2 260 CYS n 
2 261 ARG n 
2 262 LEU n 
2 263 PHE n 
2 264 ASP n 
2 265 LEU n 
2 266 ARG n 
2 267 ALA n 
2 268 ASP n 
2 269 GLN n 
2 270 GLU n 
2 271 LEU n 
2 272 MET n 
2 273 THR n 
2 274 TYR n 
2 275 SER n 
2 276 HIS n 
2 277 ASP n 
2 278 ASN n 
2 279 ILE n 
2 280 ILE n 
2 281 CYS n 
2 282 GLY n 
2 283 ILE n 
2 284 THR n 
2 285 SER n 
2 286 VAL n 
2 287 SER n 
2 288 PHE n 
2 289 SER n 
2 290 LYS n 
2 291 SER n 
2 292 GLY n 
2 293 ARG n 
2 294 LEU n 
2 295 LEU n 
2 296 LEU n 
2 297 ALA n 
2 298 GLY n 
2 299 TYR n 
2 300 ASP n 
2 301 ASP n 
2 302 PHE n 
2 303 ASN n 
2 304 CYS n 
2 305 ASN n 
2 306 VAL n 
2 307 TRP n 
2 308 ASP n 
2 309 ALA n 
2 310 LEU n 
2 311 LYS n 
2 312 ALA n 
2 313 ASP n 
2 314 ARG n 
2 315 ALA n 
2 316 GLY n 
2 317 VAL n 
2 318 LEU n 
2 319 ALA n 
2 320 GLY n 
2 321 HIS n 
2 322 ASP n 
2 323 ASN n 
2 324 ARG n 
2 325 VAL n 
2 326 SER n 
2 327 CYS n 
2 328 LEU n 
2 329 GLY n 
2 330 VAL n 
2 331 THR n 
2 332 ASP n 
2 333 ASP n 
2 334 GLY n 
2 335 MET n 
2 336 ALA n 
2 337 VAL n 
2 338 ALA n 
2 339 THR n 
2 340 GLY n 
2 341 SER n 
2 342 TRP n 
2 343 ASP n 
2 344 SER n 
2 345 PHE n 
2 346 LEU n 
2 347 LYS n 
2 348 ILE n 
2 349 TRP n 
2 350 ASN n 
2 351 GLY n 
2 352 SER n 
2 353 SER n 
2 354 GLY n 
2 355 GLY n 
2 356 GLY n 
2 357 GLY n 
2 358 SER n 
2 359 GLY n 
2 360 GLY n 
2 361 GLY n 
2 362 GLY n 
2 363 SER n 
2 364 SER n 
2 365 GLY n 
2 366 VAL n 
2 367 SER n 
2 368 GLY n 
2 369 TRP n 
2 370 ARG n 
2 371 LEU n 
2 372 PHE n 
2 373 LYS n 
2 374 LYS n 
2 375 ILE n 
2 376 SER n 
3 1   MET n 
3 2   ALA n 
3 3   SER n 
3 4   ASN n 
3 5   ASN n 
3 6   THR n 
3 7   ALA n 
3 8   SER n 
3 9   ILE n 
3 10  ALA n 
3 11  GLN n 
3 12  ALA n 
3 13  ARG n 
3 14  LYS n 
3 15  LEU n 
3 16  VAL n 
3 17  GLU n 
3 18  GLN n 
3 19  LEU n 
3 20  LYS n 
3 21  MET n 
3 22  GLU n 
3 23  ALA n 
3 24  ASN n 
3 25  ILE n 
3 26  ASP n 
3 27  ARG n 
3 28  ILE n 
3 29  LYS n 
3 30  VAL n 
3 31  SER n 
3 32  LYS n 
3 33  ALA n 
3 34  ALA n 
3 35  ALA n 
3 36  ASP n 
3 37  LEU n 
3 38  MET n 
3 39  ALA n 
3 40  TYR n 
3 41  CYS n 
3 42  GLU n 
3 43  ALA n 
3 44  HIS n 
3 45  ALA n 
3 46  LYS n 
3 47  GLU n 
3 48  ASP n 
3 49  PRO n 
3 50  LEU n 
3 51  LEU n 
3 52  THR n 
3 53  PRO n 
3 54  VAL n 
3 55  PRO n 
3 56  ALA n 
3 57  SER n 
3 58  GLU n 
3 59  ASN n 
3 60  PRO n 
3 61  PHE n 
3 62  ARG n 
3 63  GLU n 
3 64  LYS n 
3 65  LYS n 
3 66  PHE n 
3 67  PHE n 
3 68  CYS n 
3 69  ALA n 
3 70  ILE n 
3 71  LEU n 
4 1   ASP n 
4 2   VAL n 
4 3   GLN n 
4 4   LEU n 
4 5   VAL n 
4 6   GLU n 
4 7   SER n 
4 8   GLY n 
4 9   GLY n 
4 10  GLY n 
4 11  LEU n 
4 12  VAL n 
4 13  GLN n 
4 14  PRO n 
4 15  GLY n 
4 16  GLY n 
4 17  SER n 
4 18  ARG n 
4 19  LYS n 
4 20  LEU n 
4 21  SER n 
4 22  CYS n 
4 23  SER n 
4 24  ALA n 
4 25  SER n 
4 26  GLY n 
4 27  PHE n 
4 28  ALA n 
4 29  PHE n 
4 30  SER n 
4 31  SER n 
4 32  PHE n 
4 33  GLY n 
4 34  MET n 
4 35  HIS n 
4 36  TRP n 
4 37  VAL n 
4 38  ARG n 
4 39  GLN n 
4 40  ALA n 
4 41  PRO n 
4 42  GLU n 
4 43  LYS n 
4 44  GLY n 
4 45  LEU n 
4 46  GLU n 
4 47  TRP n 
4 48  VAL n 
4 49  ALA n 
4 50  TYR n 
4 51  ILE n 
4 52  SER n 
4 53  SER n 
4 54  GLY n 
4 55  SER n 
4 56  GLY n 
4 57  THR n 
4 58  ILE n 
4 59  TYR n 
4 60  TYR n 
4 61  ALA n 
4 62  ASP n 
4 63  THR n 
4 64  VAL n 
4 65  LYS n 
4 66  GLY n 
4 67  ARG n 
4 68  PHE n 
4 69  THR n 
4 70  ILE n 
4 71  SER n 
4 72  ARG n 
4 73  ASP n 
4 74  ASP n 
4 75  PRO n 
4 76  LYS n 
4 77  ASN n 
4 78  THR n 
4 79  LEU n 
4 80  PHE n 
4 81  LEU n 
4 82  GLN n 
4 83  MET n 
4 84  THR n 
4 85  SER n 
4 86  LEU n 
4 87  ARG n 
4 88  SER n 
4 89  GLU n 
4 90  ASP n 
4 91  THR n 
4 92  ALA n 
4 93  MET n 
4 94  TYR n 
4 95  TYR n 
4 96  CYS n 
4 97  VAL n 
4 98  ARG n 
4 99  SER n 
4 100 ILE n 
4 101 TYR n 
4 102 TYR n 
4 103 TYR n 
4 104 GLY n 
4 105 SER n 
4 106 SER n 
4 107 PRO n 
4 108 PHE n 
4 109 ASP n 
4 110 PHE n 
4 111 TRP n 
4 112 GLY n 
4 113 GLN n 
4 114 GLY n 
4 115 THR n 
4 116 THR n 
4 117 LEU n 
4 118 THR n 
4 119 VAL n 
4 120 SER n 
4 121 SER n 
4 122 GLY n 
4 123 GLY n 
4 124 GLY n 
4 125 GLY n 
4 126 SER n 
4 127 GLY n 
4 128 GLY n 
4 129 GLY n 
4 130 GLY n 
4 131 SER n 
4 132 GLY n 
4 133 GLY n 
4 134 GLY n 
4 135 GLY n 
4 136 SER n 
4 137 ASP n 
4 138 ILE n 
4 139 VAL n 
4 140 MET n 
4 141 THR n 
4 142 GLN n 
4 143 ALA n 
4 144 THR n 
4 145 SER n 
4 146 SER n 
4 147 VAL n 
4 148 PRO n 
4 149 VAL n 
4 150 THR n 
4 151 PRO n 
4 152 GLY n 
4 153 GLU n 
4 154 SER n 
4 155 VAL n 
4 156 SER n 
4 157 ILE n 
4 158 SER n 
4 159 CYS n 
4 160 ARG n 
4 161 SER n 
4 162 SER n 
4 163 LYS n 
4 164 SER n 
4 165 LEU n 
4 166 LEU n 
4 167 HIS n 
4 168 SER n 
4 169 ASN n 
4 170 GLY n 
4 171 ASN n 
4 172 THR n 
4 173 TYR n 
4 174 LEU n 
4 175 TYR n 
4 176 TRP n 
4 177 PHE n 
4 178 LEU n 
4 179 GLN n 
4 180 ARG n 
4 181 PRO n 
4 182 GLY n 
4 183 GLN n 
4 184 SER n 
4 185 PRO n 
4 186 GLN n 
4 187 LEU n 
4 188 LEU n 
4 189 ILE n 
4 190 TYR n 
4 191 ARG n 
4 192 MET n 
4 193 SER n 
4 194 ASN n 
4 195 LEU n 
4 196 ALA n 
4 197 SER n 
4 198 GLY n 
4 199 VAL n 
4 200 PRO n 
4 201 ASP n 
4 202 ARG n 
4 203 PHE n 
4 204 SER n 
4 205 GLY n 
4 206 SER n 
4 207 GLY n 
4 208 SER n 
4 209 GLY n 
4 210 THR n 
4 211 ALA n 
4 212 PHE n 
4 213 THR n 
4 214 LEU n 
4 215 THR n 
4 216 ILE n 
4 217 SER n 
4 218 ARG n 
4 219 LEU n 
4 220 GLU n 
4 221 ALA n 
4 222 GLU n 
4 223 ASP n 
4 224 VAL n 
4 225 GLY n 
4 226 VAL n 
4 227 TYR n 
4 228 TYR n 
4 229 CYS n 
4 230 MET n 
4 231 GLN n 
4 232 HIS n 
4 233 LEU n 
4 234 GLU n 
4 235 TYR n 
4 236 PRO n 
4 237 LEU n 
4 238 THR n 
4 239 PHE n 
4 240 GLY n 
4 241 ALA n 
4 242 GLY n 
4 243 THR n 
4 244 LYS n 
4 245 LEU n 
4 246 GLU n 
4 247 LEU n 
4 248 LEU n 
4 249 GLU n 
4 250 GLU n 
4 251 ASN n 
4 252 LEU n 
4 253 TYR n 
4 254 PHE n 
4 255 GLN n 
5 1   ASP n 
5 2   TYR n 
5 3   LYS n 
5 4   ASP n 
5 5   ASP n 
5 6   ASP n 
5 7   ASP n 
5 8   HIS n 
5 9   HIS n 
5 10  HIS n 
5 11  HIS n 
5 12  HIS n 
5 13  HIS n 
5 14  HIS n 
5 15  HIS n 
5 16  GLY n 
5 17  GLN n 
5 18  PRO n 
5 19  GLY n 
5 20  ASN n 
5 21  GLY n 
5 22  SER n 
5 23  ALA n 
5 24  PHE n 
5 25  LEU n 
5 26  LEU n 
5 27  ALA n 
5 28  PRO n 
5 29  ASN n 
5 30  GLY n 
5 31  SER n 
5 32  HIS n 
5 33  ALA n 
5 34  PRO n 
5 35  ASP n 
5 36  HIS n 
5 37  ASN n 
5 38  VAL n 
5 39  THR n 
5 40  GLN n 
5 41  GLN n 
5 42  ARG n 
5 43  ASP n 
5 44  GLU n 
5 45  GLU n 
5 46  ASN n 
5 47  LEU n 
5 48  TYR n 
5 49  PHE n 
5 50  GLN n 
5 51  GLY n 
5 52  VAL n 
5 53  ASP n 
5 54  MET n 
5 55  SER n 
5 56  VAL n 
5 57  GLY n 
5 58  ALA n 
5 59  MET n 
5 60  LYS n 
5 61  LYS n 
5 62  GLY n 
5 63  VAL n 
5 64  GLY n 
5 65  ARG n 
5 66  ALA n 
5 67  VAL n 
5 68  GLY n 
5 69  LEU n 
5 70  GLY n 
5 71  GLY n 
5 72  GLY n 
5 73  SER n 
5 74  GLY n 
5 75  CYS n 
5 76  GLN n 
5 77  ALA n 
5 78  THR n 
5 79  GLU n 
5 80  GLU n 
5 81  ASP n 
5 82  PRO n 
5 83  LEU n 
5 84  PRO n 
5 85  ASN n 
5 86  CYS n 
5 87  GLY n 
5 88  ALA n 
5 89  CYS n 
5 90  ALA n 
5 91  PRO n 
5 92  GLY n 
5 93  GLN n 
5 94  GLY n 
5 95  GLY n 
5 96  ARG n 
5 97  ARG n 
5 98  TRP n 
5 99  ARG n 
5 100 LEU n 
5 101 PRO n 
5 102 GLN n 
5 103 PRO n 
5 104 ALA n 
5 105 TRP n 
5 106 VAL n 
5 107 GLU n 
5 108 GLY n 
5 109 SER n 
5 110 SER n 
5 111 ALA n 
5 112 ARG n 
5 113 LEU n 
5 114 TRP n 
5 115 GLU n 
5 116 GLN n 
5 117 ALA n 
5 118 THR n 
5 119 GLY n 
5 120 THR n 
5 121 GLY n 
5 122 TRP n 
5 123 MET n 
5 124 ASP n 
5 125 LEU n 
5 126 GLU n 
5 127 ALA n 
5 128 SER n 
5 129 LEU n 
5 130 LEU n 
5 131 PRO n 
5 132 THR n 
5 133 GLY n 
5 134 PRO n 
5 135 ASN n 
5 136 ALA n 
5 137 SER n 
5 138 ASN n 
5 139 THR n 
5 140 SER n 
5 141 ASP n 
5 142 GLY n 
5 143 PRO n 
5 144 ASP n 
5 145 ASN n 
5 146 LEU n 
5 147 THR n 
5 148 SER n 
5 149 ALA n 
5 150 GLY n 
5 151 SER n 
5 152 PRO n 
5 153 PRO n 
5 154 ARG n 
5 155 THR n 
5 156 GLY n 
5 157 SER n 
5 158 ILE n 
5 159 SER n 
5 160 TYR n 
5 161 ILE n 
5 162 ASN n 
5 163 ILE n 
5 164 ILE n 
5 165 MET n 
5 166 PRO n 
5 167 SER n 
5 168 VAL n 
5 169 PHE n 
5 170 GLY n 
5 171 THR n 
5 172 ILE n 
5 173 CYS n 
5 174 LEU n 
5 175 LEU n 
5 176 GLY n 
5 177 ILE n 
5 178 ILE n 
5 179 GLY n 
5 180 ASN n 
5 181 SER n 
5 182 THR n 
5 183 VAL n 
5 184 ILE n 
5 185 PHE n 
5 186 ALA n 
5 187 VAL n 
5 188 VAL n 
5 189 LYS n 
5 190 LYS n 
5 191 SER n 
5 192 LYS n 
5 193 LEU n 
5 194 HIS n 
5 195 TRP n 
5 196 CYS n 
5 197 ASN n 
5 198 ASN n 
5 199 VAL n 
5 200 PRO n 
5 201 ASP n 
5 202 ILE n 
5 203 PHE n 
5 204 ILE n 
5 205 ILE n 
5 206 ASN n 
5 207 LEU n 
5 208 SER n 
5 209 VAL n 
5 210 VAL n 
5 211 ASP n 
5 212 LEU n 
5 213 LEU n 
5 214 PHE n 
5 215 LEU n 
5 216 LEU n 
5 217 GLY n 
5 218 MET n 
5 219 PRO n 
5 220 PHE n 
5 221 MET n 
5 222 ILE n 
5 223 HIS n 
5 224 GLN n 
5 225 LEU n 
5 226 MET n 
5 227 GLY n 
5 228 ASN n 
5 229 GLY n 
5 230 VAL n 
5 231 TRP n 
5 232 HIS n 
5 233 PHE n 
5 234 GLY n 
5 235 GLU n 
5 236 THR n 
5 237 MET n 
5 238 CYS n 
5 239 THR n 
5 240 LEU n 
5 241 ILE n 
5 242 THR n 
5 243 ALA n 
5 244 MET n 
5 245 ASP n 
5 246 ALA n 
5 247 ASN n 
5 248 SER n 
5 249 GLN n 
5 250 PHE n 
5 251 THR n 
5 252 SER n 
5 253 THR n 
5 254 TYR n 
5 255 ILE n 
5 256 LEU n 
5 257 THR n 
5 258 ALA n 
5 259 MET n 
5 260 ALA n 
5 261 ILE n 
5 262 ASP n 
5 263 ARG n 
5 264 TYR n 
5 265 LEU n 
5 266 ALA n 
5 267 THR n 
5 268 VAL n 
5 269 HIS n 
5 270 PRO n 
5 271 ILE n 
5 272 SER n 
5 273 SER n 
5 274 THR n 
5 275 LYS n 
5 276 PHE n 
5 277 ARG n 
5 278 LYS n 
5 279 PRO n 
5 280 SER n 
5 281 VAL n 
5 282 ALA n 
5 283 THR n 
5 284 LEU n 
5 285 VAL n 
5 286 ILE n 
5 287 CYS n 
5 288 LEU n 
5 289 LEU n 
5 290 TRP n 
5 291 ALA n 
5 292 LEU n 
5 293 SER n 
5 294 PHE n 
5 295 ILE n 
5 296 SER n 
5 297 ILE n 
5 298 THR n 
5 299 PRO n 
5 300 VAL n 
5 301 TRP n 
5 302 LEU n 
5 303 TYR n 
5 304 ALA n 
5 305 ARG n 
5 306 LEU n 
5 307 ILE n 
5 308 PRO n 
5 309 PHE n 
5 310 PRO n 
5 311 GLY n 
5 312 GLY n 
5 313 ALA n 
5 314 VAL n 
5 315 GLY n 
5 316 CYS n 
5 317 GLY n 
5 318 ILE n 
5 319 ARG n 
5 320 LEU n 
5 321 PRO n 
5 322 ASN n 
5 323 PRO n 
5 324 ASP n 
5 325 THR n 
5 326 ASP n 
5 327 LEU n 
5 328 TYR n 
5 329 TRP n 
5 330 PHE n 
5 331 THR n 
5 332 LEU n 
5 333 TYR n 
5 334 GLN n 
5 335 PHE n 
5 336 PHE n 
5 337 LEU n 
5 338 ALA n 
5 339 PHE n 
5 340 ALA n 
5 341 LEU n 
5 342 PRO n 
5 343 PHE n 
5 344 VAL n 
5 345 VAL n 
5 346 ILE n 
5 347 THR n 
5 348 ALA n 
5 349 ALA n 
5 350 TYR n 
5 351 VAL n 
5 352 ARG n 
5 353 ILE n 
5 354 LEU n 
5 355 GLN n 
5 356 ARG n 
5 357 MET n 
5 358 THR n 
5 359 SER n 
5 360 SER n 
5 361 VAL n 
5 362 ALA n 
5 363 PRO n 
5 364 ALA n 
5 365 SER n 
5 366 GLN n 
5 367 ARG n 
5 368 SER n 
5 369 ILE n 
5 370 ARG n 
5 371 LEU n 
5 372 ARG n 
5 373 THR n 
5 374 LYS n 
5 375 ARG n 
5 376 VAL n 
5 377 THR n 
5 378 ARG n 
5 379 THR n 
5 380 ALA n 
5 381 ILE n 
5 382 ALA n 
5 383 ILE n 
5 384 CYS n 
5 385 LEU n 
5 386 VAL n 
5 387 PHE n 
5 388 PHE n 
5 389 VAL n 
5 390 CYS n 
5 391 TRP n 
5 392 ALA n 
5 393 PRO n 
5 394 TYR n 
5 395 TYR n 
5 396 VAL n 
5 397 LEU n 
5 398 GLN n 
5 399 LEU n 
5 400 THR n 
5 401 GLN n 
5 402 LEU n 
5 403 SER n 
5 404 ILE n 
5 405 SER n 
5 406 ARG n 
5 407 PRO n 
5 408 THR n 
5 409 LEU n 
5 410 THR n 
5 411 PHE n 
5 412 VAL n 
5 413 TYR n 
5 414 LEU n 
5 415 TYR n 
5 416 ASN n 
5 417 ALA n 
5 418 ALA n 
5 419 ILE n 
5 420 SER n 
5 421 LEU n 
5 422 GLY n 
5 423 TYR n 
5 424 ALA n 
5 425 ASN n 
5 426 SER n 
5 427 CYS n 
5 428 LEU n 
5 429 ASN n 
5 430 PRO n 
5 431 PHE n 
5 432 VAL n 
5 433 TYR n 
5 434 ILE n 
5 435 VAL n 
5 436 LEU n 
5 437 CYS n 
5 438 GLU n 
5 439 THR n 
5 440 PHE n 
5 441 ARG n 
5 442 LYS n 
5 443 ARG n 
5 444 LEU n 
5 445 VAL n 
5 446 LEU n 
5 447 SER n 
5 448 VAL n 
5 449 LYS n 
5 450 HIS n 
5 451 MET n 
5 452 GLY n 
5 453 SER n 
5 454 SER n 
5 455 GLY n 
5 456 GLY n 
5 457 GLY n 
5 458 GLY n 
5 459 SER n 
5 460 GLY n 
5 461 GLY n 
5 462 GLY n 
5 463 GLY n 
5 464 SER n 
5 465 SER n 
5 466 GLY n 
5 467 VAL n 
5 468 PHE n 
5 469 THR n 
5 470 LEU n 
5 471 GLU n 
5 472 ASP n 
5 473 PHE n 
5 474 VAL n 
5 475 GLY n 
5 476 ASP n 
5 477 TRP n 
5 478 GLU n 
5 479 GLN n 
5 480 THR n 
5 481 ALA n 
5 482 ALA n 
5 483 TYR n 
5 484 ASN n 
5 485 LEU n 
5 486 ASP n 
5 487 GLN n 
5 488 VAL n 
5 489 LEU n 
5 490 GLU n 
5 491 GLN n 
5 492 GLY n 
5 493 GLY n 
5 494 VAL n 
5 495 SER n 
5 496 SER n 
5 497 LEU n 
5 498 LEU n 
5 499 GLN n 
5 500 ASN n 
5 501 LEU n 
5 502 ALA n 
5 503 VAL n 
5 504 SER n 
5 505 VAL n 
5 506 THR n 
5 507 PRO n 
5 508 ILE n 
5 509 GLN n 
5 510 ARG n 
5 511 ILE n 
5 512 VAL n 
5 513 ARG n 
5 514 SER n 
5 515 GLY n 
5 516 GLU n 
5 517 ASN n 
5 518 ALA n 
5 519 LEU n 
5 520 LYS n 
5 521 ILE n 
5 522 ASP n 
5 523 ILE n 
5 524 HIS n 
5 525 VAL n 
5 526 ILE n 
5 527 ILE n 
5 528 PRO n 
5 529 TYR n 
5 530 GLU n 
5 531 GLY n 
5 532 LEU n 
5 533 SER n 
5 534 ALA n 
5 535 ASP n 
5 536 GLN n 
5 537 MET n 
5 538 ALA n 
5 539 GLN n 
5 540 ILE n 
5 541 GLU n 
5 542 GLU n 
5 543 VAL n 
5 544 PHE n 
5 545 LYS n 
5 546 VAL n 
5 547 VAL n 
5 548 TYR n 
5 549 PRO n 
5 550 VAL n 
5 551 ASP n 
5 552 ASP n 
5 553 HIS n 
5 554 HIS n 
5 555 PHE n 
5 556 LYS n 
5 557 VAL n 
5 558 ILE n 
5 559 LEU n 
5 560 PRO n 
5 561 TYR n 
5 562 GLY n 
5 563 THR n 
5 564 LEU n 
5 565 VAL n 
5 566 ILE n 
5 567 ASP n 
5 568 GLY n 
5 569 VAL n 
5 570 THR n 
5 571 PRO n 
5 572 ASN n 
5 573 MET n 
5 574 LEU n 
5 575 ASN n 
5 576 TYR n 
5 577 PHE n 
5 578 GLY n 
5 579 ARG n 
5 580 PRO n 
5 581 TYR n 
5 582 GLU n 
5 583 GLY n 
5 584 ILE n 
5 585 ALA n 
5 586 VAL n 
5 587 PHE n 
5 588 ASP n 
5 589 GLY n 
5 590 LYS n 
5 591 LYS n 
5 592 ILE n 
5 593 THR n 
5 594 VAL n 
5 595 THR n 
5 596 GLY n 
5 597 THR n 
5 598 LEU n 
5 599 TRP n 
5 600 ASN n 
5 601 GLY n 
5 602 ASN n 
5 603 LYS n 
5 604 ILE n 
5 605 ILE n 
5 606 ASP n 
5 607 GLU n 
5 608 ARG n 
5 609 LEU n 
5 610 ILE n 
5 611 THR n 
5 612 PRO n 
5 613 ASP n 
5 614 GLY n 
5 615 SER n 
5 616 MET n 
5 617 LEU n 
5 618 PHE n 
5 619 ARG n 
5 620 VAL n 
5 621 THR n 
5 622 ILE n 
5 623 ASN n 
5 624 SER n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1   354 human ? GNAI1                ? ? ? ? ? ? 'Homo sapiens'        9606  ? ? ? ? ? ? ? ? 
'Baculovirus expression vector pFastBac1-HM' 274590 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1   376 human ? GNB1                 ? ? ? ? ? ? 'Homo sapiens'        9606  ? ? ? ? ? ? ? ? 
'Baculovirus expression vector pFastBac1-HM' 274590 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1   71  human ? GNG2                 ? ? ? ? ? ? 'Homo sapiens'        9606  ? ? ? ? ? ? ? ? 
'Baculovirus expression vector pFastBac1-HM' 274590 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 'Biological sequence' 1   255 ?     ? ?                    ? ? ? ? ? ? 'synthetic construct' 32630 ? ? ? ? ? ? ? ? 
'Baculovirus expression vector pFastBac1-HM' 274590 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
5 1 sample 'Biological sequence' 1   53  human ? ?                    ? ? ? ? ? ? 'Homo sapiens'        9606  ? ? ? ? ? ? ? ? 
'Baculovirus expression vector pFastBac1-HM' 274590 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
5 2 sample 'Biological sequence' 54  449 human ? 'MCHR1, GPR24, SLC1' ? ? ? ? ? ? 'Homo sapiens'        9606  ? ? ? ? ? ? ? ? 
'Baculovirus expression vector pFastBac1-HM' 274590 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
5 3 sample 'Biological sequence' 450 624 human ? ?                    ? ? ? ? ? ? 'Homo sapiens'        9606  ? ? ? ? ? ? ? ? 
'Baculovirus expression vector pFastBac1-HM' 274590 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   GLY 2   2   ?   ?   ?   A . n 
A 1 3   CYS 3   3   ?   ?   ?   A . n 
A 1 4   THR 4   4   4   THR THR A . n 
A 1 5   LEU 5   5   5   LEU LEU A . n 
A 1 6   SER 6   6   6   SER SER A . n 
A 1 7   ALA 7   7   7   ALA ALA A . n 
A 1 8   GLU 8   8   8   GLU GLU A . n 
A 1 9   ASP 9   9   9   ASP ASP A . n 
A 1 10  LYS 10  10  10  LYS LYS A . n 
A 1 11  ALA 11  11  11  ALA ALA A . n 
A 1 12  ALA 12  12  12  ALA ALA A . n 
A 1 13  VAL 13  13  13  VAL VAL A . n 
A 1 14  GLU 14  14  14  GLU GLU A . n 
A 1 15  ARG 15  15  15  ARG ARG A . n 
A 1 16  SER 16  16  16  SER SER A . n 
A 1 17  LYS 17  17  17  LYS LYS A . n 
A 1 18  MET 18  18  18  MET MET A . n 
A 1 19  ILE 19  19  19  ILE ILE A . n 
A 1 20  ASP 20  20  20  ASP ASP A . n 
A 1 21  ARG 21  21  21  ARG ARG A . n 
A 1 22  ASN 22  22  22  ASN ASN A . n 
A 1 23  LEU 23  23  23  LEU LEU A . n 
A 1 24  ARG 24  24  24  ARG ARG A . n 
A 1 25  GLU 25  25  25  GLU GLU A . n 
A 1 26  ASP 26  26  26  ASP ASP A . n 
A 1 27  GLY 27  27  27  GLY GLY A . n 
A 1 28  GLU 28  28  28  GLU GLU A . n 
A 1 29  LYS 29  29  29  LYS LYS A . n 
A 1 30  ALA 30  30  30  ALA ALA A . n 
A 1 31  ALA 31  31  31  ALA ALA A . n 
A 1 32  ARG 32  32  32  ARG ARG A . n 
A 1 33  GLU 33  33  33  GLU GLU A . n 
A 1 34  VAL 34  34  34  VAL VAL A . n 
A 1 35  LYS 35  35  35  LYS LYS A . n 
A 1 36  LEU 36  36  36  LEU LEU A . n 
A 1 37  LEU 37  37  37  LEU LEU A . n 
A 1 38  LEU 38  38  38  LEU LEU A . n 
A 1 39  LEU 39  39  39  LEU LEU A . n 
A 1 40  GLY 40  40  40  GLY GLY A . n 
A 1 41  ALA 41  41  41  ALA ALA A . n 
A 1 42  GLY 42  42  42  GLY GLY A . n 
A 1 43  GLU 43  43  43  GLU GLU A . n 
A 1 44  SER 44  44  44  SER SER A . n 
A 1 45  GLY 45  45  45  GLY GLY A . n 
A 1 46  LYS 46  46  46  LYS LYS A . n 
A 1 47  ASN 47  47  47  ASN ASN A . n 
A 1 48  THR 48  48  48  THR THR A . n 
A 1 49  ILE 49  49  49  ILE ILE A . n 
A 1 50  VAL 50  50  50  VAL VAL A . n 
A 1 51  LYS 51  51  51  LYS LYS A . n 
A 1 52  GLN 52  52  52  GLN GLN A . n 
A 1 53  MET 53  53  53  MET MET A . n 
A 1 54  LYS 54  54  54  LYS LYS A . n 
A 1 55  ILE 55  55  ?   ?   ?   A . n 
A 1 56  ILE 56  56  ?   ?   ?   A . n 
A 1 57  HIS 57  57  ?   ?   ?   A . n 
A 1 58  GLU 58  58  ?   ?   ?   A . n 
A 1 59  ALA 59  59  ?   ?   ?   A . n 
A 1 60  GLY 60  60  ?   ?   ?   A . n 
A 1 61  TYR 61  61  ?   ?   ?   A . n 
A 1 62  SER 62  62  ?   ?   ?   A . n 
A 1 63  GLU 63  63  ?   ?   ?   A . n 
A 1 64  GLU 64  64  ?   ?   ?   A . n 
A 1 65  GLU 65  65  ?   ?   ?   A . n 
A 1 66  CYS 66  66  ?   ?   ?   A . n 
A 1 67  LYS 67  67  ?   ?   ?   A . n 
A 1 68  GLN 68  68  ?   ?   ?   A . n 
A 1 69  TYR 69  69  ?   ?   ?   A . n 
A 1 70  LYS 70  70  ?   ?   ?   A . n 
A 1 71  ALA 71  71  ?   ?   ?   A . n 
A 1 72  VAL 72  72  ?   ?   ?   A . n 
A 1 73  VAL 73  73  ?   ?   ?   A . n 
A 1 74  TYR 74  74  ?   ?   ?   A . n 
A 1 75  SER 75  75  ?   ?   ?   A . n 
A 1 76  ASN 76  76  ?   ?   ?   A . n 
A 1 77  THR 77  77  ?   ?   ?   A . n 
A 1 78  ILE 78  78  ?   ?   ?   A . n 
A 1 79  GLN 79  79  ?   ?   ?   A . n 
A 1 80  SER 80  80  ?   ?   ?   A . n 
A 1 81  ILE 81  81  ?   ?   ?   A . n 
A 1 82  ILE 82  82  ?   ?   ?   A . n 
A 1 83  ALA 83  83  ?   ?   ?   A . n 
A 1 84  ILE 84  84  ?   ?   ?   A . n 
A 1 85  ILE 85  85  ?   ?   ?   A . n 
A 1 86  ARG 86  86  ?   ?   ?   A . n 
A 1 87  ALA 87  87  ?   ?   ?   A . n 
A 1 88  MET 88  88  ?   ?   ?   A . n 
A 1 89  GLY 89  89  ?   ?   ?   A . n 
A 1 90  ARG 90  90  ?   ?   ?   A . n 
A 1 91  LEU 91  91  ?   ?   ?   A . n 
A 1 92  LYS 92  92  ?   ?   ?   A . n 
A 1 93  ILE 93  93  ?   ?   ?   A . n 
A 1 94  ASP 94  94  ?   ?   ?   A . n 
A 1 95  PHE 95  95  ?   ?   ?   A . n 
A 1 96  GLY 96  96  ?   ?   ?   A . n 
A 1 97  ASP 97  97  ?   ?   ?   A . n 
A 1 98  SER 98  98  ?   ?   ?   A . n 
A 1 99  ALA 99  99  ?   ?   ?   A . n 
A 1 100 ARG 100 100 ?   ?   ?   A . n 
A 1 101 ALA 101 101 ?   ?   ?   A . n 
A 1 102 ASP 102 102 ?   ?   ?   A . n 
A 1 103 ASP 103 103 ?   ?   ?   A . n 
A 1 104 ALA 104 104 ?   ?   ?   A . n 
A 1 105 ARG 105 105 ?   ?   ?   A . n 
A 1 106 GLN 106 106 ?   ?   ?   A . n 
A 1 107 LEU 107 107 ?   ?   ?   A . n 
A 1 108 PHE 108 108 ?   ?   ?   A . n 
A 1 109 VAL 109 109 ?   ?   ?   A . n 
A 1 110 LEU 110 110 ?   ?   ?   A . n 
A 1 111 ALA 111 111 ?   ?   ?   A . n 
A 1 112 GLY 112 112 ?   ?   ?   A . n 
A 1 113 ALA 113 113 ?   ?   ?   A . n 
A 1 114 ALA 114 114 ?   ?   ?   A . n 
A 1 115 GLU 115 115 ?   ?   ?   A . n 
A 1 116 GLU 116 116 ?   ?   ?   A . n 
A 1 117 GLY 117 117 ?   ?   ?   A . n 
A 1 118 PHE 118 118 ?   ?   ?   A . n 
A 1 119 MET 119 119 ?   ?   ?   A . n 
A 1 120 THR 120 120 ?   ?   ?   A . n 
A 1 121 ALA 121 121 ?   ?   ?   A . n 
A 1 122 GLU 122 122 ?   ?   ?   A . n 
A 1 123 LEU 123 123 ?   ?   ?   A . n 
A 1 124 ALA 124 124 ?   ?   ?   A . n 
A 1 125 GLY 125 125 ?   ?   ?   A . n 
A 1 126 VAL 126 126 ?   ?   ?   A . n 
A 1 127 ILE 127 127 ?   ?   ?   A . n 
A 1 128 LYS 128 128 ?   ?   ?   A . n 
A 1 129 ARG 129 129 ?   ?   ?   A . n 
A 1 130 LEU 130 130 ?   ?   ?   A . n 
A 1 131 TRP 131 131 ?   ?   ?   A . n 
A 1 132 LYS 132 132 ?   ?   ?   A . n 
A 1 133 ASP 133 133 ?   ?   ?   A . n 
A 1 134 SER 134 134 ?   ?   ?   A . n 
A 1 135 GLY 135 135 ?   ?   ?   A . n 
A 1 136 VAL 136 136 ?   ?   ?   A . n 
A 1 137 GLN 137 137 ?   ?   ?   A . n 
A 1 138 ALA 138 138 ?   ?   ?   A . n 
A 1 139 CYS 139 139 ?   ?   ?   A . n 
A 1 140 PHE 140 140 ?   ?   ?   A . n 
A 1 141 ASN 141 141 ?   ?   ?   A . n 
A 1 142 ARG 142 142 ?   ?   ?   A . n 
A 1 143 SER 143 143 ?   ?   ?   A . n 
A 1 144 ARG 144 144 ?   ?   ?   A . n 
A 1 145 GLU 145 145 ?   ?   ?   A . n 
A 1 146 TYR 146 146 ?   ?   ?   A . n 
A 1 147 GLN 147 147 ?   ?   ?   A . n 
A 1 148 LEU 148 148 ?   ?   ?   A . n 
A 1 149 ASN 149 149 ?   ?   ?   A . n 
A 1 150 ASP 150 150 ?   ?   ?   A . n 
A 1 151 SER 151 151 ?   ?   ?   A . n 
A 1 152 ALA 152 152 ?   ?   ?   A . n 
A 1 153 ALA 153 153 ?   ?   ?   A . n 
A 1 154 TYR 154 154 ?   ?   ?   A . n 
A 1 155 TYR 155 155 ?   ?   ?   A . n 
A 1 156 LEU 156 156 ?   ?   ?   A . n 
A 1 157 ASN 157 157 ?   ?   ?   A . n 
A 1 158 ASP 158 158 ?   ?   ?   A . n 
A 1 159 LEU 159 159 ?   ?   ?   A . n 
A 1 160 ASP 160 160 ?   ?   ?   A . n 
A 1 161 ARG 161 161 ?   ?   ?   A . n 
A 1 162 ILE 162 162 ?   ?   ?   A . n 
A 1 163 ALA 163 163 ?   ?   ?   A . n 
A 1 164 GLN 164 164 ?   ?   ?   A . n 
A 1 165 PRO 165 165 ?   ?   ?   A . n 
A 1 166 ASN 166 166 ?   ?   ?   A . n 
A 1 167 TYR 167 167 ?   ?   ?   A . n 
A 1 168 ILE 168 168 ?   ?   ?   A . n 
A 1 169 PRO 169 169 ?   ?   ?   A . n 
A 1 170 THR 170 170 ?   ?   ?   A . n 
A 1 171 GLN 171 171 ?   ?   ?   A . n 
A 1 172 GLN 172 172 ?   ?   ?   A . n 
A 1 173 ASP 173 173 ?   ?   ?   A . n 
A 1 174 VAL 174 174 ?   ?   ?   A . n 
A 1 175 LEU 175 175 ?   ?   ?   A . n 
A 1 176 ARG 176 176 ?   ?   ?   A . n 
A 1 177 THR 177 177 ?   ?   ?   A . n 
A 1 178 ARG 178 178 ?   ?   ?   A . n 
A 1 179 VAL 179 179 ?   ?   ?   A . n 
A 1 180 LYS 180 180 ?   ?   ?   A . n 
A 1 181 THR 181 181 ?   ?   ?   A . n 
A 1 182 THR 182 182 182 THR THR A . n 
A 1 183 GLY 183 183 183 GLY GLY A . n 
A 1 184 ILE 184 184 184 ILE ILE A . n 
A 1 185 VAL 185 185 185 VAL VAL A . n 
A 1 186 GLU 186 186 186 GLU GLU A . n 
A 1 187 THR 187 187 187 THR THR A . n 
A 1 188 HIS 188 188 188 HIS HIS A . n 
A 1 189 PHE 189 189 189 PHE PHE A . n 
A 1 190 THR 190 190 190 THR THR A . n 
A 1 191 PHE 191 191 191 PHE PHE A . n 
A 1 192 LYS 192 192 192 LYS LYS A . n 
A 1 193 ASP 193 193 193 ASP ASP A . n 
A 1 194 LEU 194 194 194 LEU LEU A . n 
A 1 195 HIS 195 195 195 HIS HIS A . n 
A 1 196 PHE 196 196 196 PHE PHE A . n 
A 1 197 LYS 197 197 197 LYS LYS A . n 
A 1 198 MET 198 198 198 MET MET A . n 
A 1 199 PHE 199 199 199 PHE PHE A . n 
A 1 200 ASP 200 200 200 ASP ASP A . n 
A 1 201 VAL 201 201 201 VAL VAL A . n 
A 1 202 GLY 202 202 202 GLY GLY A . n 
A 1 203 ALA 203 203 203 ALA ALA A . n 
A 1 204 GLN 204 204 204 GLN GLN A . n 
A 1 205 ARG 205 205 205 ARG ARG A . n 
A 1 206 SER 206 206 206 SER SER A . n 
A 1 207 GLU 207 207 207 GLU GLU A . n 
A 1 208 ARG 208 208 208 ARG ARG A . n 
A 1 209 LYS 209 209 209 LYS LYS A . n 
A 1 210 LYS 210 210 210 LYS LYS A . n 
A 1 211 TRP 211 211 211 TRP TRP A . n 
A 1 212 ILE 212 212 212 ILE ILE A . n 
A 1 213 HIS 213 213 213 HIS HIS A . n 
A 1 214 CYS 214 214 214 CYS CYS A . n 
A 1 215 PHE 215 215 215 PHE PHE A . n 
A 1 216 GLU 216 216 216 GLU GLU A . n 
A 1 217 GLY 217 217 217 GLY GLY A . n 
A 1 218 VAL 218 218 218 VAL VAL A . n 
A 1 219 THR 219 219 219 THR THR A . n 
A 1 220 ALA 220 220 220 ALA ALA A . n 
A 1 221 ILE 221 221 221 ILE ILE A . n 
A 1 222 ILE 222 222 222 ILE ILE A . n 
A 1 223 PHE 223 223 223 PHE PHE A . n 
A 1 224 CYS 224 224 224 CYS CYS A . n 
A 1 225 VAL 225 225 225 VAL VAL A . n 
A 1 226 ALA 226 226 226 ALA ALA A . n 
A 1 227 LEU 227 227 227 LEU LEU A . n 
A 1 228 SER 228 228 228 SER SER A . n 
A 1 229 ASP 229 229 229 ASP ASP A . n 
A 1 230 TYR 230 230 230 TYR TYR A . n 
A 1 231 ASP 231 231 231 ASP ASP A . n 
A 1 232 LEU 232 232 232 LEU LEU A . n 
A 1 233 VAL 233 233 233 VAL VAL A . n 
A 1 234 LEU 234 234 234 LEU LEU A . n 
A 1 235 ALA 235 235 235 ALA ALA A . n 
A 1 236 GLU 236 236 236 GLU GLU A . n 
A 1 237 ASP 237 237 237 ASP ASP A . n 
A 1 238 GLU 238 238 238 GLU GLU A . n 
A 1 239 GLU 239 239 239 GLU GLU A . n 
A 1 240 MET 240 240 240 MET MET A . n 
A 1 241 ASN 241 241 241 ASN ASN A . n 
A 1 242 ARG 242 242 242 ARG ARG A . n 
A 1 243 MET 243 243 243 MET MET A . n 
A 1 244 HIS 244 244 244 HIS HIS A . n 
A 1 245 ALA 245 245 245 ALA ALA A . n 
A 1 246 SER 246 246 246 SER SER A . n 
A 1 247 MET 247 247 247 MET MET A . n 
A 1 248 LYS 248 248 248 LYS LYS A . n 
A 1 249 LEU 249 249 249 LEU LEU A . n 
A 1 250 PHE 250 250 250 PHE PHE A . n 
A 1 251 ASP 251 251 251 ASP ASP A . n 
A 1 252 SER 252 252 252 SER SER A . n 
A 1 253 ILE 253 253 253 ILE ILE A . n 
A 1 254 CYS 254 254 254 CYS CYS A . n 
A 1 255 ASN 255 255 255 ASN ASN A . n 
A 1 256 ASN 256 256 256 ASN ASN A . n 
A 1 257 LYS 257 257 257 LYS LYS A . n 
A 1 258 TRP 258 258 258 TRP TRP A . n 
A 1 259 PHE 259 259 259 PHE PHE A . n 
A 1 260 THR 260 260 260 THR THR A . n 
A 1 261 ASP 261 261 261 ASP ASP A . n 
A 1 262 THR 262 262 262 THR THR A . n 
A 1 263 SER 263 263 263 SER SER A . n 
A 1 264 ILE 264 264 264 ILE ILE A . n 
A 1 265 ILE 265 265 265 ILE ILE A . n 
A 1 266 LEU 266 266 266 LEU LEU A . n 
A 1 267 PHE 267 267 267 PHE PHE A . n 
A 1 268 LEU 268 268 268 LEU LEU A . n 
A 1 269 ASN 269 269 269 ASN ASN A . n 
A 1 270 LYS 270 270 270 LYS LYS A . n 
A 1 271 LYS 271 271 271 LYS LYS A . n 
A 1 272 ASP 272 272 272 ASP ASP A . n 
A 1 273 LEU 273 273 273 LEU LEU A . n 
A 1 274 PHE 274 274 274 PHE PHE A . n 
A 1 275 GLU 275 275 275 GLU GLU A . n 
A 1 276 GLU 276 276 276 GLU GLU A . n 
A 1 277 LYS 277 277 277 LYS LYS A . n 
A 1 278 ILE 278 278 278 ILE ILE A . n 
A 1 279 LYS 279 279 279 LYS LYS A . n 
A 1 280 LYS 280 280 280 LYS LYS A . n 
A 1 281 SER 281 281 281 SER SER A . n 
A 1 282 PRO 282 282 282 PRO PRO A . n 
A 1 283 LEU 283 283 283 LEU LEU A . n 
A 1 284 THR 284 284 284 THR THR A . n 
A 1 285 ILE 285 285 285 ILE ILE A . n 
A 1 286 CYS 286 286 286 CYS CYS A . n 
A 1 287 TYR 287 287 287 TYR TYR A . n 
A 1 288 PRO 288 288 288 PRO PRO A . n 
A 1 289 GLU 289 289 289 GLU GLU A . n 
A 1 290 TYR 290 290 290 TYR TYR A . n 
A 1 291 ALA 291 291 291 ALA ALA A . n 
A 1 292 GLY 292 292 292 GLY GLY A . n 
A 1 293 SER 293 293 293 SER SER A . n 
A 1 294 ASN 294 294 294 ASN ASN A . n 
A 1 295 THR 295 295 295 THR THR A . n 
A 1 296 TYR 296 296 296 TYR TYR A . n 
A 1 297 GLU 297 297 297 GLU GLU A . n 
A 1 298 GLU 298 298 298 GLU GLU A . n 
A 1 299 ALA 299 299 299 ALA ALA A . n 
A 1 300 ALA 300 300 300 ALA ALA A . n 
A 1 301 ALA 301 301 301 ALA ALA A . n 
A 1 302 TYR 302 302 302 TYR TYR A . n 
A 1 303 ILE 303 303 303 ILE ILE A . n 
A 1 304 GLN 304 304 304 GLN GLN A . n 
A 1 305 CYS 305 305 305 CYS CYS A . n 
A 1 306 GLN 306 306 306 GLN GLN A . n 
A 1 307 PHE 307 307 307 PHE PHE A . n 
A 1 308 GLU 308 308 308 GLU GLU A . n 
A 1 309 ASP 309 309 309 ASP ASP A . n 
A 1 310 LEU 310 310 310 LEU LEU A . n 
A 1 311 ASN 311 311 311 ASN ASN A . n 
A 1 312 LYS 312 312 312 LYS LYS A . n 
A 1 313 ARG 313 313 313 ARG ARG A . n 
A 1 314 LYS 314 314 314 LYS LYS A . n 
A 1 315 ASP 315 315 315 ASP ASP A . n 
A 1 316 THR 316 316 316 THR THR A . n 
A 1 317 LYS 317 317 317 LYS LYS A . n 
A 1 318 GLU 318 318 318 GLU GLU A . n 
A 1 319 ILE 319 319 319 ILE ILE A . n 
A 1 320 TYR 320 320 320 TYR TYR A . n 
A 1 321 THR 321 321 321 THR THR A . n 
A 1 322 HIS 322 322 322 HIS HIS A . n 
A 1 323 PHE 323 323 323 PHE PHE A . n 
A 1 324 THR 324 324 324 THR THR A . n 
A 1 325 CYS 325 325 325 CYS CYS A . n 
A 1 326 SER 326 326 326 SER SER A . n 
A 1 327 THR 327 327 327 THR THR A . n 
A 1 328 ASP 328 328 328 ASP ASP A . n 
A 1 329 THR 329 329 329 THR THR A . n 
A 1 330 LYS 330 330 330 LYS LYS A . n 
A 1 331 ASN 331 331 331 ASN ASN A . n 
A 1 332 VAL 332 332 332 VAL VAL A . n 
A 1 333 GLN 333 333 333 GLN GLN A . n 
A 1 334 PHE 334 334 334 PHE PHE A . n 
A 1 335 VAL 335 335 335 VAL VAL A . n 
A 1 336 PHE 336 336 336 PHE PHE A . n 
A 1 337 ASP 337 337 337 ASP ASP A . n 
A 1 338 ALA 338 338 338 ALA ALA A . n 
A 1 339 VAL 339 339 339 VAL VAL A . n 
A 1 340 THR 340 340 340 THR THR A . n 
A 1 341 ASP 341 341 341 ASP ASP A . n 
A 1 342 VAL 342 342 342 VAL VAL A . n 
A 1 343 ILE 343 343 343 ILE ILE A . n 
A 1 344 ILE 344 344 344 ILE ILE A . n 
A 1 345 LYS 345 345 345 LYS LYS A . n 
A 1 346 ASN 346 346 346 ASN ASN A . n 
A 1 347 ASN 347 347 347 ASN ASN A . n 
A 1 348 LEU 348 348 348 LEU LEU A . n 
A 1 349 LYS 349 349 349 LYS LYS A . n 
A 1 350 ASP 350 350 350 ASP ASP A . n 
A 1 351 CYS 351 351 351 CYS CYS A . n 
A 1 352 GLY 352 352 352 GLY GLY A . n 
A 1 353 LEU 353 353 353 LEU LEU A . n 
A 1 354 PHE 354 354 354 PHE PHE A . n 
B 2 1   MET 1   -9  ?   ?   ?   B . n 
B 2 2   HIS 2   -8  ?   ?   ?   B . n 
B 2 3   HIS 3   -7  ?   ?   ?   B . n 
B 2 4   HIS 4   -6  ?   ?   ?   B . n 
B 2 5   HIS 5   -5  ?   ?   ?   B . n 
B 2 6   HIS 6   -4  ?   ?   ?   B . n 
B 2 7   HIS 7   -3  ?   ?   ?   B . n 
B 2 8   GLY 8   -2  ?   ?   ?   B . n 
B 2 9   SER 9   -1  ?   ?   ?   B . n 
B 2 10  SER 10  0   ?   ?   ?   B . n 
B 2 11  GLY 11  1   ?   ?   ?   B . n 
B 2 12  SER 12  2   2   SER SER B . n 
B 2 13  GLU 13  3   3   GLU GLU B . n 
B 2 14  LEU 14  4   4   LEU LEU B . n 
B 2 15  ASP 15  5   5   ASP ASP B . n 
B 2 16  GLN 16  6   6   GLN GLN B . n 
B 2 17  LEU 17  7   7   LEU LEU B . n 
B 2 18  ARG 18  8   8   ARG ARG B . n 
B 2 19  GLN 19  9   9   GLN GLN B . n 
B 2 20  GLU 20  10  10  GLU GLU B . n 
B 2 21  ALA 21  11  11  ALA ALA B . n 
B 2 22  GLU 22  12  12  GLU GLU B . n 
B 2 23  GLN 23  13  13  GLN GLN B . n 
B 2 24  LEU 24  14  14  LEU LEU B . n 
B 2 25  LYS 25  15  15  LYS LYS B . n 
B 2 26  ASN 26  16  16  ASN ASN B . n 
B 2 27  GLN 27  17  17  GLN GLN B . n 
B 2 28  ILE 28  18  18  ILE ILE B . n 
B 2 29  ARG 29  19  19  ARG ARG B . n 
B 2 30  ASP 30  20  20  ASP ASP B . n 
B 2 31  ALA 31  21  21  ALA ALA B . n 
B 2 32  ARG 32  22  22  ARG ARG B . n 
B 2 33  LYS 33  23  23  LYS LYS B . n 
B 2 34  ALA 34  24  24  ALA ALA B . n 
B 2 35  CYS 35  25  25  CYS CYS B . n 
B 2 36  ALA 36  26  26  ALA ALA B . n 
B 2 37  ASP 37  27  27  ASP ASP B . n 
B 2 38  ALA 38  28  28  ALA ALA B . n 
B 2 39  THR 39  29  29  THR THR B . n 
B 2 40  LEU 40  30  30  LEU LEU B . n 
B 2 41  SER 41  31  31  SER SER B . n 
B 2 42  GLN 42  32  32  GLN GLN B . n 
B 2 43  ILE 43  33  33  ILE ILE B . n 
B 2 44  THR 44  34  34  THR THR B . n 
B 2 45  ASN 45  35  35  ASN ASN B . n 
B 2 46  ASN 46  36  36  ASN ASN B . n 
B 2 47  ILE 47  37  37  ILE ILE B . n 
B 2 48  ASP 48  38  38  ASP ASP B . n 
B 2 49  PRO 49  39  39  PRO PRO B . n 
B 2 50  VAL 50  40  40  VAL VAL B . n 
B 2 51  GLY 51  41  41  GLY GLY B . n 
B 2 52  ARG 52  42  42  ARG ARG B . n 
B 2 53  ILE 53  43  43  ILE ILE B . n 
B 2 54  GLN 54  44  44  GLN GLN B . n 
B 2 55  MET 55  45  45  MET MET B . n 
B 2 56  ARG 56  46  46  ARG ARG B . n 
B 2 57  THR 57  47  47  THR THR B . n 
B 2 58  ARG 58  48  48  ARG ARG B . n 
B 2 59  ARG 59  49  49  ARG ARG B . n 
B 2 60  THR 60  50  50  THR THR B . n 
B 2 61  LEU 61  51  51  LEU LEU B . n 
B 2 62  ARG 62  52  52  ARG ARG B . n 
B 2 63  GLY 63  53  53  GLY GLY B . n 
B 2 64  HIS 64  54  54  HIS HIS B . n 
B 2 65  LEU 65  55  55  LEU LEU B . n 
B 2 66  ALA 66  56  56  ALA ALA B . n 
B 2 67  LYS 67  57  57  LYS LYS B . n 
B 2 68  ILE 68  58  58  ILE ILE B . n 
B 2 69  TYR 69  59  59  TYR TYR B . n 
B 2 70  ALA 70  60  60  ALA ALA B . n 
B 2 71  MET 71  61  61  MET MET B . n 
B 2 72  HIS 72  62  62  HIS HIS B . n 
B 2 73  TRP 73  63  63  TRP TRP B . n 
B 2 74  GLY 74  64  64  GLY GLY B . n 
B 2 75  THR 75  65  65  THR THR B . n 
B 2 76  ASP 76  66  66  ASP ASP B . n 
B 2 77  SER 77  67  67  SER SER B . n 
B 2 78  ARG 78  68  68  ARG ARG B . n 
B 2 79  LEU 79  69  69  LEU LEU B . n 
B 2 80  LEU 80  70  70  LEU LEU B . n 
B 2 81  VAL 81  71  71  VAL VAL B . n 
B 2 82  SER 82  72  72  SER SER B . n 
B 2 83  ALA 83  73  73  ALA ALA B . n 
B 2 84  SER 84  74  74  SER SER B . n 
B 2 85  GLN 85  75  75  GLN GLN B . n 
B 2 86  ASP 86  76  76  ASP ASP B . n 
B 2 87  GLY 87  77  77  GLY GLY B . n 
B 2 88  LYS 88  78  78  LYS LYS B . n 
B 2 89  LEU 89  79  79  LEU LEU B . n 
B 2 90  ILE 90  80  80  ILE ILE B . n 
B 2 91  ILE 91  81  81  ILE ILE B . n 
B 2 92  TRP 92  82  82  TRP TRP B . n 
B 2 93  ASP 93  83  83  ASP ASP B . n 
B 2 94  SER 94  84  84  SER SER B . n 
B 2 95  TYR 95  85  85  TYR TYR B . n 
B 2 96  THR 96  86  86  THR THR B . n 
B 2 97  THR 97  87  87  THR THR B . n 
B 2 98  ASN 98  88  88  ASN ASN B . n 
B 2 99  LYS 99  89  89  LYS LYS B . n 
B 2 100 VAL 100 90  90  VAL VAL B . n 
B 2 101 HIS 101 91  91  HIS HIS B . n 
B 2 102 ALA 102 92  92  ALA ALA B . n 
B 2 103 ILE 103 93  93  ILE ILE B . n 
B 2 104 PRO 104 94  94  PRO PRO B . n 
B 2 105 LEU 105 95  95  LEU LEU B . n 
B 2 106 ARG 106 96  96  ARG ARG B . n 
B 2 107 SER 107 97  97  SER SER B . n 
B 2 108 SER 108 98  98  SER SER B . n 
B 2 109 TRP 109 99  99  TRP TRP B . n 
B 2 110 VAL 110 100 100 VAL VAL B . n 
B 2 111 MET 111 101 101 MET MET B . n 
B 2 112 THR 112 102 102 THR THR B . n 
B 2 113 CYS 113 103 103 CYS CYS B . n 
B 2 114 ALA 114 104 104 ALA ALA B . n 
B 2 115 TYR 115 105 105 TYR TYR B . n 
B 2 116 ALA 116 106 106 ALA ALA B . n 
B 2 117 PRO 117 107 107 PRO PRO B . n 
B 2 118 SER 118 108 108 SER SER B . n 
B 2 119 GLY 119 109 109 GLY GLY B . n 
B 2 120 ASN 120 110 110 ASN ASN B . n 
B 2 121 TYR 121 111 111 TYR TYR B . n 
B 2 122 VAL 122 112 112 VAL VAL B . n 
B 2 123 ALA 123 113 113 ALA ALA B . n 
B 2 124 CYS 124 114 114 CYS CYS B . n 
B 2 125 GLY 125 115 115 GLY GLY B . n 
B 2 126 GLY 126 116 116 GLY GLY B . n 
B 2 127 LEU 127 117 117 LEU LEU B . n 
B 2 128 ASP 128 118 118 ASP ASP B . n 
B 2 129 ASN 129 119 119 ASN ASN B . n 
B 2 130 ILE 130 120 120 ILE ILE B . n 
B 2 131 CYS 131 121 121 CYS CYS B . n 
B 2 132 SER 132 122 122 SER SER B . n 
B 2 133 ILE 133 123 123 ILE ILE B . n 
B 2 134 TYR 134 124 124 TYR TYR B . n 
B 2 135 ASN 135 125 125 ASN ASN B . n 
B 2 136 LEU 136 126 126 LEU LEU B . n 
B 2 137 LYS 137 127 127 LYS LYS B . n 
B 2 138 THR 138 128 128 THR THR B . n 
B 2 139 ARG 139 129 129 ARG ARG B . n 
B 2 140 GLU 140 130 130 GLU GLU B . n 
B 2 141 GLY 141 131 131 GLY GLY B . n 
B 2 142 ASN 142 132 132 ASN ASN B . n 
B 2 143 VAL 143 133 133 VAL VAL B . n 
B 2 144 ARG 144 134 134 ARG ARG B . n 
B 2 145 VAL 145 135 135 VAL VAL B . n 
B 2 146 SER 146 136 136 SER SER B . n 
B 2 147 ARG 147 137 137 ARG ARG B . n 
B 2 148 GLU 148 138 138 GLU GLU B . n 
B 2 149 LEU 149 139 139 LEU LEU B . n 
B 2 150 ALA 150 140 140 ALA ALA B . n 
B 2 151 GLY 151 141 141 GLY GLY B . n 
B 2 152 HIS 152 142 142 HIS HIS B . n 
B 2 153 THR 153 143 143 THR THR B . n 
B 2 154 GLY 154 144 144 GLY GLY B . n 
B 2 155 TYR 155 145 145 TYR TYR B . n 
B 2 156 LEU 156 146 146 LEU LEU B . n 
B 2 157 SER 157 147 147 SER SER B . n 
B 2 158 CYS 158 148 148 CYS CYS B . n 
B 2 159 CYS 159 149 149 CYS CYS B . n 
B 2 160 ARG 160 150 150 ARG ARG B . n 
B 2 161 PHE 161 151 151 PHE PHE B . n 
B 2 162 LEU 162 152 152 LEU LEU B . n 
B 2 163 ASP 163 153 153 ASP ASP B . n 
B 2 164 ASP 164 154 154 ASP ASP B . n 
B 2 165 ASN 165 155 155 ASN ASN B . n 
B 2 166 GLN 166 156 156 GLN GLN B . n 
B 2 167 ILE 167 157 157 ILE ILE B . n 
B 2 168 VAL 168 158 158 VAL VAL B . n 
B 2 169 THR 169 159 159 THR THR B . n 
B 2 170 SER 170 160 160 SER SER B . n 
B 2 171 SER 171 161 161 SER SER B . n 
B 2 172 GLY 172 162 162 GLY GLY B . n 
B 2 173 ASP 173 163 163 ASP ASP B . n 
B 2 174 THR 174 164 164 THR THR B . n 
B 2 175 THR 175 165 165 THR THR B . n 
B 2 176 CYS 176 166 166 CYS CYS B . n 
B 2 177 ALA 177 167 167 ALA ALA B . n 
B 2 178 LEU 178 168 168 LEU LEU B . n 
B 2 179 TRP 179 169 169 TRP TRP B . n 
B 2 180 ASP 180 170 170 ASP ASP B . n 
B 2 181 ILE 181 171 171 ILE ILE B . n 
B 2 182 GLU 182 172 172 GLU GLU B . n 
B 2 183 THR 183 173 173 THR THR B . n 
B 2 184 GLY 184 174 174 GLY GLY B . n 
B 2 185 GLN 185 175 175 GLN GLN B . n 
B 2 186 GLN 186 176 176 GLN GLN B . n 
B 2 187 THR 187 177 177 THR THR B . n 
B 2 188 THR 188 178 178 THR THR B . n 
B 2 189 THR 189 179 179 THR THR B . n 
B 2 190 PHE 190 180 180 PHE PHE B . n 
B 2 191 THR 191 181 181 THR THR B . n 
B 2 192 GLY 192 182 182 GLY GLY B . n 
B 2 193 HIS 193 183 183 HIS HIS B . n 
B 2 194 THR 194 184 184 THR THR B . n 
B 2 195 GLY 195 185 185 GLY GLY B . n 
B 2 196 ASP 196 186 186 ASP ASP B . n 
B 2 197 VAL 197 187 187 VAL VAL B . n 
B 2 198 MET 198 188 188 MET MET B . n 
B 2 199 SER 199 189 189 SER SER B . n 
B 2 200 LEU 200 190 190 LEU LEU B . n 
B 2 201 SER 201 191 191 SER SER B . n 
B 2 202 LEU 202 192 192 LEU LEU B . n 
B 2 203 ALA 203 193 193 ALA ALA B . n 
B 2 204 PRO 204 194 194 PRO PRO B . n 
B 2 205 ASP 205 195 195 ASP ASP B . n 
B 2 206 THR 206 196 196 THR THR B . n 
B 2 207 ARG 207 197 197 ARG ARG B . n 
B 2 208 LEU 208 198 198 LEU LEU B . n 
B 2 209 PHE 209 199 199 PHE PHE B . n 
B 2 210 VAL 210 200 200 VAL VAL B . n 
B 2 211 SER 211 201 201 SER SER B . n 
B 2 212 GLY 212 202 202 GLY GLY B . n 
B 2 213 ALA 213 203 203 ALA ALA B . n 
B 2 214 CYS 214 204 204 CYS CYS B . n 
B 2 215 ASP 215 205 205 ASP ASP B . n 
B 2 216 ALA 216 206 206 ALA ALA B . n 
B 2 217 SER 217 207 207 SER SER B . n 
B 2 218 ALA 218 208 208 ALA ALA B . n 
B 2 219 LYS 219 209 209 LYS LYS B . n 
B 2 220 LEU 220 210 210 LEU LEU B . n 
B 2 221 TRP 221 211 211 TRP TRP B . n 
B 2 222 ASP 222 212 212 ASP ASP B . n 
B 2 223 VAL 223 213 213 VAL VAL B . n 
B 2 224 ARG 224 214 214 ARG ARG B . n 
B 2 225 GLU 225 215 215 GLU GLU B . n 
B 2 226 GLY 226 216 216 GLY GLY B . n 
B 2 227 MET 227 217 217 MET MET B . n 
B 2 228 CYS 228 218 218 CYS CYS B . n 
B 2 229 ARG 229 219 219 ARG ARG B . n 
B 2 230 GLN 230 220 220 GLN GLN B . n 
B 2 231 THR 231 221 221 THR THR B . n 
B 2 232 PHE 232 222 222 PHE PHE B . n 
B 2 233 THR 233 223 223 THR THR B . n 
B 2 234 GLY 234 224 224 GLY GLY B . n 
B 2 235 HIS 235 225 225 HIS HIS B . n 
B 2 236 GLU 236 226 226 GLU GLU B . n 
B 2 237 SER 237 227 227 SER SER B . n 
B 2 238 ASP 238 228 228 ASP ASP B . n 
B 2 239 ILE 239 229 229 ILE ILE B . n 
B 2 240 ASN 240 230 230 ASN ASN B . n 
B 2 241 ALA 241 231 231 ALA ALA B . n 
B 2 242 ILE 242 232 232 ILE ILE B . n 
B 2 243 CYS 243 233 233 CYS CYS B . n 
B 2 244 PHE 244 234 234 PHE PHE B . n 
B 2 245 PHE 245 235 235 PHE PHE B . n 
B 2 246 PRO 246 236 236 PRO PRO B . n 
B 2 247 ASN 247 237 237 ASN ASN B . n 
B 2 248 GLY 248 238 238 GLY GLY B . n 
B 2 249 ASN 249 239 239 ASN ASN B . n 
B 2 250 ALA 250 240 240 ALA ALA B . n 
B 2 251 PHE 251 241 241 PHE PHE B . n 
B 2 252 ALA 252 242 242 ALA ALA B . n 
B 2 253 THR 253 243 243 THR THR B . n 
B 2 254 GLY 254 244 244 GLY GLY B . n 
B 2 255 SER 255 245 245 SER SER B . n 
B 2 256 ASP 256 246 246 ASP ASP B . n 
B 2 257 ASP 257 247 247 ASP ASP B . n 
B 2 258 ALA 258 248 248 ALA ALA B . n 
B 2 259 THR 259 249 249 THR THR B . n 
B 2 260 CYS 260 250 250 CYS CYS B . n 
B 2 261 ARG 261 251 251 ARG ARG B . n 
B 2 262 LEU 262 252 252 LEU LEU B . n 
B 2 263 PHE 263 253 253 PHE PHE B . n 
B 2 264 ASP 264 254 254 ASP ASP B . n 
B 2 265 LEU 265 255 255 LEU LEU B . n 
B 2 266 ARG 266 256 256 ARG ARG B . n 
B 2 267 ALA 267 257 257 ALA ALA B . n 
B 2 268 ASP 268 258 258 ASP ASP B . n 
B 2 269 GLN 269 259 259 GLN GLN B . n 
B 2 270 GLU 270 260 260 GLU GLU B . n 
B 2 271 LEU 271 261 261 LEU LEU B . n 
B 2 272 MET 272 262 262 MET MET B . n 
B 2 273 THR 273 263 263 THR THR B . n 
B 2 274 TYR 274 264 264 TYR TYR B . n 
B 2 275 SER 275 265 265 SER SER B . n 
B 2 276 HIS 276 266 266 HIS HIS B . n 
B 2 277 ASP 277 267 267 ASP ASP B . n 
B 2 278 ASN 278 268 268 ASN ASN B . n 
B 2 279 ILE 279 269 269 ILE ILE B . n 
B 2 280 ILE 280 270 270 ILE ILE B . n 
B 2 281 CYS 281 271 271 CYS CYS B . n 
B 2 282 GLY 282 272 272 GLY GLY B . n 
B 2 283 ILE 283 273 273 ILE ILE B . n 
B 2 284 THR 284 274 274 THR THR B . n 
B 2 285 SER 285 275 275 SER SER B . n 
B 2 286 VAL 286 276 276 VAL VAL B . n 
B 2 287 SER 287 277 277 SER SER B . n 
B 2 288 PHE 288 278 278 PHE PHE B . n 
B 2 289 SER 289 279 279 SER SER B . n 
B 2 290 LYS 290 280 280 LYS LYS B . n 
B 2 291 SER 291 281 281 SER SER B . n 
B 2 292 GLY 292 282 282 GLY GLY B . n 
B 2 293 ARG 293 283 283 ARG ARG B . n 
B 2 294 LEU 294 284 284 LEU LEU B . n 
B 2 295 LEU 295 285 285 LEU LEU B . n 
B 2 296 LEU 296 286 286 LEU LEU B . n 
B 2 297 ALA 297 287 287 ALA ALA B . n 
B 2 298 GLY 298 288 288 GLY GLY B . n 
B 2 299 TYR 299 289 289 TYR TYR B . n 
B 2 300 ASP 300 290 290 ASP ASP B . n 
B 2 301 ASP 301 291 291 ASP ASP B . n 
B 2 302 PHE 302 292 292 PHE PHE B . n 
B 2 303 ASN 303 293 293 ASN ASN B . n 
B 2 304 CYS 304 294 294 CYS CYS B . n 
B 2 305 ASN 305 295 295 ASN ASN B . n 
B 2 306 VAL 306 296 296 VAL VAL B . n 
B 2 307 TRP 307 297 297 TRP TRP B . n 
B 2 308 ASP 308 298 298 ASP ASP B . n 
B 2 309 ALA 309 299 299 ALA ALA B . n 
B 2 310 LEU 310 300 300 LEU LEU B . n 
B 2 311 LYS 311 301 301 LYS LYS B . n 
B 2 312 ALA 312 302 302 ALA ALA B . n 
B 2 313 ASP 313 303 303 ASP ASP B . n 
B 2 314 ARG 314 304 304 ARG ARG B . n 
B 2 315 ALA 315 305 305 ALA ALA B . n 
B 2 316 GLY 316 306 306 GLY GLY B . n 
B 2 317 VAL 317 307 307 VAL VAL B . n 
B 2 318 LEU 318 308 308 LEU LEU B . n 
B 2 319 ALA 319 309 309 ALA ALA B . n 
B 2 320 GLY 320 310 310 GLY GLY B . n 
B 2 321 HIS 321 311 311 HIS HIS B . n 
B 2 322 ASP 322 312 312 ASP ASP B . n 
B 2 323 ASN 323 313 313 ASN ASN B . n 
B 2 324 ARG 324 314 314 ARG ARG B . n 
B 2 325 VAL 325 315 315 VAL VAL B . n 
B 2 326 SER 326 316 316 SER SER B . n 
B 2 327 CYS 327 317 317 CYS CYS B . n 
B 2 328 LEU 328 318 318 LEU LEU B . n 
B 2 329 GLY 329 319 319 GLY GLY B . n 
B 2 330 VAL 330 320 320 VAL VAL B . n 
B 2 331 THR 331 321 321 THR THR B . n 
B 2 332 ASP 332 322 322 ASP ASP B . n 
B 2 333 ASP 333 323 323 ASP ASP B . n 
B 2 334 GLY 334 324 324 GLY GLY B . n 
B 2 335 MET 335 325 325 MET MET B . n 
B 2 336 ALA 336 326 326 ALA ALA B . n 
B 2 337 VAL 337 327 327 VAL VAL B . n 
B 2 338 ALA 338 328 328 ALA ALA B . n 
B 2 339 THR 339 329 329 THR THR B . n 
B 2 340 GLY 340 330 330 GLY GLY B . n 
B 2 341 SER 341 331 331 SER SER B . n 
B 2 342 TRP 342 332 332 TRP TRP B . n 
B 2 343 ASP 343 333 333 ASP ASP B . n 
B 2 344 SER 344 334 334 SER SER B . n 
B 2 345 PHE 345 335 335 PHE PHE B . n 
B 2 346 LEU 346 336 336 LEU LEU B . n 
B 2 347 LYS 347 337 337 LYS LYS B . n 
B 2 348 ILE 348 338 338 ILE ILE B . n 
B 2 349 TRP 349 339 339 TRP TRP B . n 
B 2 350 ASN 350 340 340 ASN ASN B . n 
B 2 351 GLY 351 341 341 GLY GLY B . n 
B 2 352 SER 352 342 342 SER SER B . n 
B 2 353 SER 353 343 343 SER SER B . n 
B 2 354 GLY 354 344 ?   ?   ?   B . n 
B 2 355 GLY 355 345 ?   ?   ?   B . n 
B 2 356 GLY 356 346 ?   ?   ?   B . n 
B 2 357 GLY 357 347 ?   ?   ?   B . n 
B 2 358 SER 358 348 ?   ?   ?   B . n 
B 2 359 GLY 359 349 ?   ?   ?   B . n 
B 2 360 GLY 360 350 ?   ?   ?   B . n 
B 2 361 GLY 361 351 ?   ?   ?   B . n 
B 2 362 GLY 362 352 ?   ?   ?   B . n 
B 2 363 SER 363 353 ?   ?   ?   B . n 
B 2 364 SER 364 354 ?   ?   ?   B . n 
B 2 365 GLY 365 355 ?   ?   ?   B . n 
B 2 366 VAL 366 356 ?   ?   ?   B . n 
B 2 367 SER 367 357 ?   ?   ?   B . n 
B 2 368 GLY 368 358 ?   ?   ?   B . n 
B 2 369 TRP 369 359 ?   ?   ?   B . n 
B 2 370 ARG 370 360 ?   ?   ?   B . n 
B 2 371 LEU 371 361 ?   ?   ?   B . n 
B 2 372 PHE 372 362 ?   ?   ?   B . n 
B 2 373 LYS 373 363 ?   ?   ?   B . n 
B 2 374 LYS 374 364 ?   ?   ?   B . n 
B 2 375 ILE 375 365 ?   ?   ?   B . n 
B 2 376 SER 376 366 ?   ?   ?   B . n 
C 3 1   MET 1   1   ?   ?   ?   C . n 
C 3 2   ALA 2   2   ?   ?   ?   C . n 
C 3 3   SER 3   3   ?   ?   ?   C . n 
C 3 4   ASN 4   4   ?   ?   ?   C . n 
C 3 5   ASN 5   5   ?   ?   ?   C . n 
C 3 6   THR 6   6   6   THR THR C . n 
C 3 7   ALA 7   7   7   ALA ALA C . n 
C 3 8   SER 8   8   8   SER SER C . n 
C 3 9   ILE 9   9   9   ILE ILE C . n 
C 3 10  ALA 10  10  10  ALA ALA C . n 
C 3 11  GLN 11  11  11  GLN GLN C . n 
C 3 12  ALA 12  12  12  ALA ALA C . n 
C 3 13  ARG 13  13  13  ARG ARG C . n 
C 3 14  LYS 14  14  14  LYS LYS C . n 
C 3 15  LEU 15  15  15  LEU LEU C . n 
C 3 16  VAL 16  16  16  VAL VAL C . n 
C 3 17  GLU 17  17  17  GLU GLU C . n 
C 3 18  GLN 18  18  18  GLN GLN C . n 
C 3 19  LEU 19  19  19  LEU LEU C . n 
C 3 20  LYS 20  20  20  LYS LYS C . n 
C 3 21  MET 21  21  21  MET MET C . n 
C 3 22  GLU 22  22  22  GLU GLU C . n 
C 3 23  ALA 23  23  23  ALA ALA C . n 
C 3 24  ASN 24  24  24  ASN ASN C . n 
C 3 25  ILE 25  25  25  ILE ILE C . n 
C 3 26  ASP 26  26  26  ASP ASP C . n 
C 3 27  ARG 27  27  27  ARG ARG C . n 
C 3 28  ILE 28  28  28  ILE ILE C . n 
C 3 29  LYS 29  29  29  LYS LYS C . n 
C 3 30  VAL 30  30  30  VAL VAL C . n 
C 3 31  SER 31  31  31  SER SER C . n 
C 3 32  LYS 32  32  32  LYS LYS C . n 
C 3 33  ALA 33  33  33  ALA ALA C . n 
C 3 34  ALA 34  34  34  ALA ALA C . n 
C 3 35  ALA 35  35  35  ALA ALA C . n 
C 3 36  ASP 36  36  36  ASP ASP C . n 
C 3 37  LEU 37  37  37  LEU LEU C . n 
C 3 38  MET 38  38  38  MET MET C . n 
C 3 39  ALA 39  39  39  ALA ALA C . n 
C 3 40  TYR 40  40  40  TYR TYR C . n 
C 3 41  CYS 41  41  41  CYS CYS C . n 
C 3 42  GLU 42  42  42  GLU GLU C . n 
C 3 43  ALA 43  43  43  ALA ALA C . n 
C 3 44  HIS 44  44  44  HIS HIS C . n 
C 3 45  ALA 45  45  45  ALA ALA C . n 
C 3 46  LYS 46  46  46  LYS LYS C . n 
C 3 47  GLU 47  47  47  GLU GLU C . n 
C 3 48  ASP 48  48  48  ASP ASP C . n 
C 3 49  PRO 49  49  49  PRO PRO C . n 
C 3 50  LEU 50  50  50  LEU LEU C . n 
C 3 51  LEU 51  51  51  LEU LEU C . n 
C 3 52  THR 52  52  52  THR THR C . n 
C 3 53  PRO 53  53  53  PRO PRO C . n 
C 3 54  VAL 54  54  54  VAL VAL C . n 
C 3 55  PRO 55  55  55  PRO PRO C . n 
C 3 56  ALA 56  56  56  ALA ALA C . n 
C 3 57  SER 57  57  57  SER SER C . n 
C 3 58  GLU 58  58  58  GLU GLU C . n 
C 3 59  ASN 59  59  59  ASN ASN C . n 
C 3 60  PRO 60  60  60  PRO PRO C . n 
C 3 61  PHE 61  61  61  PHE PHE C . n 
C 3 62  ARG 62  62  62  ARG ARG C . n 
C 3 63  GLU 63  63  ?   ?   ?   C . n 
C 3 64  LYS 64  64  ?   ?   ?   C . n 
C 3 65  LYS 65  65  ?   ?   ?   C . n 
C 3 66  PHE 66  66  ?   ?   ?   C . n 
C 3 67  PHE 67  67  ?   ?   ?   C . n 
C 3 68  CYS 68  68  ?   ?   ?   C . n 
C 3 69  ALA 69  69  ?   ?   ?   C . n 
C 3 70  ILE 70  70  ?   ?   ?   C . n 
C 3 71  LEU 71  71  ?   ?   ?   C . n 
D 4 1   ASP 1   1   1   ASP ASP E . n 
D 4 2   VAL 2   2   2   VAL VAL E . n 
D 4 3   GLN 3   3   3   GLN GLN E . n 
D 4 4   LEU 4   4   4   LEU LEU E . n 
D 4 5   VAL 5   5   5   VAL VAL E . n 
D 4 6   GLU 6   6   6   GLU GLU E . n 
D 4 7   SER 7   7   7   SER SER E . n 
D 4 8   GLY 8   8   8   GLY GLY E . n 
D 4 9   GLY 9   9   9   GLY GLY E . n 
D 4 10  GLY 10  10  10  GLY GLY E . n 
D 4 11  LEU 11  11  11  LEU LEU E . n 
D 4 12  VAL 12  12  12  VAL VAL E . n 
D 4 13  GLN 13  13  13  GLN GLN E . n 
D 4 14  PRO 14  14  14  PRO PRO E . n 
D 4 15  GLY 15  15  15  GLY GLY E . n 
D 4 16  GLY 16  16  16  GLY GLY E . n 
D 4 17  SER 17  17  17  SER SER E . n 
D 4 18  ARG 18  18  18  ARG ARG E . n 
D 4 19  LYS 19  19  19  LYS LYS E . n 
D 4 20  LEU 20  20  20  LEU LEU E . n 
D 4 21  SER 21  21  21  SER SER E . n 
D 4 22  CYS 22  22  22  CYS CYS E . n 
D 4 23  SER 23  23  23  SER SER E . n 
D 4 24  ALA 24  24  24  ALA ALA E . n 
D 4 25  SER 25  25  25  SER SER E . n 
D 4 26  GLY 26  26  26  GLY GLY E . n 
D 4 27  PHE 27  27  27  PHE PHE E . n 
D 4 28  ALA 28  28  28  ALA ALA E . n 
D 4 29  PHE 29  29  29  PHE PHE E . n 
D 4 30  SER 30  30  30  SER SER E . n 
D 4 31  SER 31  31  31  SER SER E . n 
D 4 32  PHE 32  32  32  PHE PHE E . n 
D 4 33  GLY 33  33  33  GLY GLY E . n 
D 4 34  MET 34  34  34  MET MET E . n 
D 4 35  HIS 35  35  35  HIS HIS E . n 
D 4 36  TRP 36  36  36  TRP TRP E . n 
D 4 37  VAL 37  37  37  VAL VAL E . n 
D 4 38  ARG 38  38  38  ARG ARG E . n 
D 4 39  GLN 39  39  39  GLN GLN E . n 
D 4 40  ALA 40  40  40  ALA ALA E . n 
D 4 41  PRO 41  41  41  PRO PRO E . n 
D 4 42  GLU 42  42  42  GLU GLU E . n 
D 4 43  LYS 43  43  43  LYS LYS E . n 
D 4 44  GLY 44  44  44  GLY GLY E . n 
D 4 45  LEU 45  45  45  LEU LEU E . n 
D 4 46  GLU 46  46  46  GLU GLU E . n 
D 4 47  TRP 47  47  47  TRP TRP E . n 
D 4 48  VAL 48  48  48  VAL VAL E . n 
D 4 49  ALA 49  49  49  ALA ALA E . n 
D 4 50  TYR 50  50  50  TYR TYR E . n 
D 4 51  ILE 51  51  51  ILE ILE E . n 
D 4 52  SER 52  52  52  SER SER E . n 
D 4 53  SER 53  53  53  SER SER E . n 
D 4 54  GLY 54  54  54  GLY GLY E . n 
D 4 55  SER 55  55  55  SER SER E . n 
D 4 56  GLY 56  56  56  GLY GLY E . n 
D 4 57  THR 57  57  57  THR THR E . n 
D 4 58  ILE 58  58  58  ILE ILE E . n 
D 4 59  TYR 59  59  59  TYR TYR E . n 
D 4 60  TYR 60  60  60  TYR TYR E . n 
D 4 61  ALA 61  61  61  ALA ALA E . n 
D 4 62  ASP 62  62  62  ASP ASP E . n 
D 4 63  THR 63  63  63  THR THR E . n 
D 4 64  VAL 64  64  64  VAL VAL E . n 
D 4 65  LYS 65  65  65  LYS LYS E . n 
D 4 66  GLY 66  66  66  GLY GLY E . n 
D 4 67  ARG 67  67  67  ARG ARG E . n 
D 4 68  PHE 68  68  68  PHE PHE E . n 
D 4 69  THR 69  69  69  THR THR E . n 
D 4 70  ILE 70  70  70  ILE ILE E . n 
D 4 71  SER 71  71  71  SER SER E . n 
D 4 72  ARG 72  72  72  ARG ARG E . n 
D 4 73  ASP 73  73  73  ASP ASP E . n 
D 4 74  ASP 74  74  74  ASP ASP E . n 
D 4 75  PRO 75  75  75  PRO PRO E . n 
D 4 76  LYS 76  76  76  LYS LYS E . n 
D 4 77  ASN 77  77  77  ASN ASN E . n 
D 4 78  THR 78  78  78  THR THR E . n 
D 4 79  LEU 79  79  79  LEU LEU E . n 
D 4 80  PHE 80  80  80  PHE PHE E . n 
D 4 81  LEU 81  81  81  LEU LEU E . n 
D 4 82  GLN 82  82  82  GLN GLN E . n 
D 4 83  MET 83  83  83  MET MET E . n 
D 4 84  THR 84  84  84  THR THR E . n 
D 4 85  SER 85  85  85  SER SER E . n 
D 4 86  LEU 86  86  86  LEU LEU E . n 
D 4 87  ARG 87  87  87  ARG ARG E . n 
D 4 88  SER 88  88  88  SER SER E . n 
D 4 89  GLU 89  89  89  GLU GLU E . n 
D 4 90  ASP 90  90  90  ASP ASP E . n 
D 4 91  THR 91  91  91  THR THR E . n 
D 4 92  ALA 92  92  92  ALA ALA E . n 
D 4 93  MET 93  93  93  MET MET E . n 
D 4 94  TYR 94  94  94  TYR TYR E . n 
D 4 95  TYR 95  95  95  TYR TYR E . n 
D 4 96  CYS 96  96  96  CYS CYS E . n 
D 4 97  VAL 97  97  97  VAL VAL E . n 
D 4 98  ARG 98  98  98  ARG ARG E . n 
D 4 99  SER 99  99  99  SER SER E . n 
D 4 100 ILE 100 100 100 ILE ILE E . n 
D 4 101 TYR 101 101 101 TYR TYR E . n 
D 4 102 TYR 102 102 102 TYR TYR E . n 
D 4 103 TYR 103 103 103 TYR TYR E . n 
D 4 104 GLY 104 104 104 GLY GLY E . n 
D 4 105 SER 105 105 105 SER SER E . n 
D 4 106 SER 106 106 106 SER SER E . n 
D 4 107 PRO 107 107 107 PRO PRO E . n 
D 4 108 PHE 108 108 108 PHE PHE E . n 
D 4 109 ASP 109 109 109 ASP ASP E . n 
D 4 110 PHE 110 110 110 PHE PHE E . n 
D 4 111 TRP 111 111 111 TRP TRP E . n 
D 4 112 GLY 112 112 112 GLY GLY E . n 
D 4 113 GLN 113 113 113 GLN GLN E . n 
D 4 114 GLY 114 114 114 GLY GLY E . n 
D 4 115 THR 115 115 115 THR THR E . n 
D 4 116 THR 116 116 116 THR THR E . n 
D 4 117 LEU 117 117 117 LEU LEU E . n 
D 4 118 THR 118 118 118 THR THR E . n 
D 4 119 VAL 119 119 119 VAL VAL E . n 
D 4 120 SER 120 120 120 SER SER E . n 
D 4 121 SER 121 121 ?   ?   ?   E . n 
D 4 122 GLY 122 122 ?   ?   ?   E . n 
D 4 123 GLY 123 123 ?   ?   ?   E . n 
D 4 124 GLY 124 124 ?   ?   ?   E . n 
D 4 125 GLY 125 125 ?   ?   ?   E . n 
D 4 126 SER 126 126 ?   ?   ?   E . n 
D 4 127 GLY 127 127 ?   ?   ?   E . n 
D 4 128 GLY 128 128 ?   ?   ?   E . n 
D 4 129 GLY 129 129 ?   ?   ?   E . n 
D 4 130 GLY 130 130 ?   ?   ?   E . n 
D 4 131 SER 131 131 ?   ?   ?   E . n 
D 4 132 GLY 132 132 ?   ?   ?   E . n 
D 4 133 GLY 133 133 ?   ?   ?   E . n 
D 4 134 GLY 134 134 ?   ?   ?   E . n 
D 4 135 GLY 135 135 ?   ?   ?   E . n 
D 4 136 SER 136 136 ?   ?   ?   E . n 
D 4 137 ASP 137 137 137 ASP ASP E . n 
D 4 138 ILE 138 138 138 ILE ILE E . n 
D 4 139 VAL 139 139 139 VAL VAL E . n 
D 4 140 MET 140 140 140 MET MET E . n 
D 4 141 THR 141 141 141 THR THR E . n 
D 4 142 GLN 142 142 142 GLN GLN E . n 
D 4 143 ALA 143 143 143 ALA ALA E . n 
D 4 144 THR 144 144 144 THR THR E . n 
D 4 145 SER 145 145 145 SER SER E . n 
D 4 146 SER 146 146 146 SER SER E . n 
D 4 147 VAL 147 147 147 VAL VAL E . n 
D 4 148 PRO 148 148 148 PRO PRO E . n 
D 4 149 VAL 149 149 149 VAL VAL E . n 
D 4 150 THR 150 150 150 THR THR E . n 
D 4 151 PRO 151 151 151 PRO PRO E . n 
D 4 152 GLY 152 152 152 GLY GLY E . n 
D 4 153 GLU 153 153 153 GLU GLU E . n 
D 4 154 SER 154 154 154 SER SER E . n 
D 4 155 VAL 155 155 155 VAL VAL E . n 
D 4 156 SER 156 156 156 SER SER E . n 
D 4 157 ILE 157 157 157 ILE ILE E . n 
D 4 158 SER 158 158 158 SER SER E . n 
D 4 159 CYS 159 159 159 CYS CYS E . n 
D 4 160 ARG 160 160 160 ARG ARG E . n 
D 4 161 SER 161 161 161 SER SER E . n 
D 4 162 SER 162 162 162 SER SER E . n 
D 4 163 LYS 163 163 163 LYS LYS E . n 
D 4 164 SER 164 164 164 SER SER E . n 
D 4 165 LEU 165 165 165 LEU LEU E . n 
D 4 166 LEU 166 166 166 LEU LEU E . n 
D 4 167 HIS 167 167 167 HIS HIS E . n 
D 4 168 SER 168 168 168 SER SER E . n 
D 4 169 ASN 169 169 169 ASN ASN E . n 
D 4 170 GLY 170 170 170 GLY GLY E . n 
D 4 171 ASN 171 171 171 ASN ASN E . n 
D 4 172 THR 172 172 172 THR THR E . n 
D 4 173 TYR 173 173 173 TYR TYR E . n 
D 4 174 LEU 174 174 174 LEU LEU E . n 
D 4 175 TYR 175 175 175 TYR TYR E . n 
D 4 176 TRP 176 176 176 TRP TRP E . n 
D 4 177 PHE 177 177 177 PHE PHE E . n 
D 4 178 LEU 178 178 178 LEU LEU E . n 
D 4 179 GLN 179 179 179 GLN GLN E . n 
D 4 180 ARG 180 180 180 ARG ARG E . n 
D 4 181 PRO 181 181 181 PRO PRO E . n 
D 4 182 GLY 182 182 182 GLY GLY E . n 
D 4 183 GLN 183 183 183 GLN GLN E . n 
D 4 184 SER 184 184 184 SER SER E . n 
D 4 185 PRO 185 185 185 PRO PRO E . n 
D 4 186 GLN 186 186 186 GLN GLN E . n 
D 4 187 LEU 187 187 187 LEU LEU E . n 
D 4 188 LEU 188 188 188 LEU LEU E . n 
D 4 189 ILE 189 189 189 ILE ILE E . n 
D 4 190 TYR 190 190 190 TYR TYR E . n 
D 4 191 ARG 191 191 191 ARG ARG E . n 
D 4 192 MET 192 192 192 MET MET E . n 
D 4 193 SER 193 193 193 SER SER E . n 
D 4 194 ASN 194 194 194 ASN ASN E . n 
D 4 195 LEU 195 195 195 LEU LEU E . n 
D 4 196 ALA 196 196 196 ALA ALA E . n 
D 4 197 SER 197 197 197 SER SER E . n 
D 4 198 GLY 198 198 198 GLY GLY E . n 
D 4 199 VAL 199 199 199 VAL VAL E . n 
D 4 200 PRO 200 200 200 PRO PRO E . n 
D 4 201 ASP 201 201 201 ASP ASP E . n 
D 4 202 ARG 202 202 202 ARG ARG E . n 
D 4 203 PHE 203 203 203 PHE PHE E . n 
D 4 204 SER 204 204 204 SER SER E . n 
D 4 205 GLY 205 205 205 GLY GLY E . n 
D 4 206 SER 206 206 206 SER SER E . n 
D 4 207 GLY 207 207 207 GLY GLY E . n 
D 4 208 SER 208 208 208 SER SER E . n 
D 4 209 GLY 209 209 209 GLY GLY E . n 
D 4 210 THR 210 210 210 THR THR E . n 
D 4 211 ALA 211 211 211 ALA ALA E . n 
D 4 212 PHE 212 212 212 PHE PHE E . n 
D 4 213 THR 213 213 213 THR THR E . n 
D 4 214 LEU 214 214 214 LEU LEU E . n 
D 4 215 THR 215 215 215 THR THR E . n 
D 4 216 ILE 216 216 216 ILE ILE E . n 
D 4 217 SER 217 217 217 SER SER E . n 
D 4 218 ARG 218 218 218 ARG ARG E . n 
D 4 219 LEU 219 219 219 LEU LEU E . n 
D 4 220 GLU 220 220 220 GLU GLU E . n 
D 4 221 ALA 221 221 221 ALA ALA E . n 
D 4 222 GLU 222 222 222 GLU GLU E . n 
D 4 223 ASP 223 223 223 ASP ASP E . n 
D 4 224 VAL 224 224 224 VAL VAL E . n 
D 4 225 GLY 225 225 225 GLY GLY E . n 
D 4 226 VAL 226 226 226 VAL VAL E . n 
D 4 227 TYR 227 227 227 TYR TYR E . n 
D 4 228 TYR 228 228 228 TYR TYR E . n 
D 4 229 CYS 229 229 229 CYS CYS E . n 
D 4 230 MET 230 230 230 MET MET E . n 
D 4 231 GLN 231 231 231 GLN GLN E . n 
D 4 232 HIS 232 232 232 HIS HIS E . n 
D 4 233 LEU 233 233 233 LEU LEU E . n 
D 4 234 GLU 234 234 234 GLU GLU E . n 
D 4 235 TYR 235 235 235 TYR TYR E . n 
D 4 236 PRO 236 236 236 PRO PRO E . n 
D 4 237 LEU 237 237 237 LEU LEU E . n 
D 4 238 THR 238 238 238 THR THR E . n 
D 4 239 PHE 239 239 239 PHE PHE E . n 
D 4 240 GLY 240 240 240 GLY GLY E . n 
D 4 241 ALA 241 241 241 ALA ALA E . n 
D 4 242 GLY 242 242 242 GLY GLY E . n 
D 4 243 THR 243 243 243 THR THR E . n 
D 4 244 LYS 244 244 244 LYS LYS E . n 
D 4 245 LEU 245 245 245 LEU LEU E . n 
D 4 246 GLU 246 246 246 GLU GLU E . n 
D 4 247 LEU 247 247 247 LEU LEU E . n 
D 4 248 LEU 248 248 ?   ?   ?   E . n 
D 4 249 GLU 249 249 ?   ?   ?   E . n 
D 4 250 GLU 250 250 ?   ?   ?   E . n 
D 4 251 ASN 251 251 ?   ?   ?   E . n 
D 4 252 LEU 252 252 ?   ?   ?   E . n 
D 4 253 TYR 253 253 ?   ?   ?   E . n 
D 4 254 PHE 254 254 ?   ?   ?   E . n 
D 4 255 GLN 255 255 ?   ?   ?   E . n 
E 5 1   ASP 1   -52 ?   ?   ?   R . n 
E 5 2   TYR 2   -51 ?   ?   ?   R . n 
E 5 3   LYS 3   -50 ?   ?   ?   R . n 
E 5 4   ASP 4   -49 ?   ?   ?   R . n 
E 5 5   ASP 5   -48 ?   ?   ?   R . n 
E 5 6   ASP 6   -47 ?   ?   ?   R . n 
E 5 7   ASP 7   -46 ?   ?   ?   R . n 
E 5 8   HIS 8   -45 ?   ?   ?   R . n 
E 5 9   HIS 9   -44 ?   ?   ?   R . n 
E 5 10  HIS 10  -43 ?   ?   ?   R . n 
E 5 11  HIS 11  -42 ?   ?   ?   R . n 
E 5 12  HIS 12  -41 ?   ?   ?   R . n 
E 5 13  HIS 13  -40 ?   ?   ?   R . n 
E 5 14  HIS 14  -39 ?   ?   ?   R . n 
E 5 15  HIS 15  -38 ?   ?   ?   R . n 
E 5 16  GLY 16  -37 ?   ?   ?   R . n 
E 5 17  GLN 17  -36 ?   ?   ?   R . n 
E 5 18  PRO 18  -35 ?   ?   ?   R . n 
E 5 19  GLY 19  -34 ?   ?   ?   R . n 
E 5 20  ASN 20  -33 ?   ?   ?   R . n 
E 5 21  GLY 21  -32 ?   ?   ?   R . n 
E 5 22  SER 22  -31 ?   ?   ?   R . n 
E 5 23  ALA 23  -30 ?   ?   ?   R . n 
E 5 24  PHE 24  -29 ?   ?   ?   R . n 
E 5 25  LEU 25  -28 ?   ?   ?   R . n 
E 5 26  LEU 26  -27 ?   ?   ?   R . n 
E 5 27  ALA 27  -26 ?   ?   ?   R . n 
E 5 28  PRO 28  -25 ?   ?   ?   R . n 
E 5 29  ASN 29  -24 ?   ?   ?   R . n 
E 5 30  GLY 30  -23 ?   ?   ?   R . n 
E 5 31  SER 31  -22 ?   ?   ?   R . n 
E 5 32  HIS 32  -21 ?   ?   ?   R . n 
E 5 33  ALA 33  -20 ?   ?   ?   R . n 
E 5 34  PRO 34  -19 ?   ?   ?   R . n 
E 5 35  ASP 35  -18 ?   ?   ?   R . n 
E 5 36  HIS 36  -17 ?   ?   ?   R . n 
E 5 37  ASN 37  -16 ?   ?   ?   R . n 
E 5 38  VAL 38  -15 ?   ?   ?   R . n 
E 5 39  THR 39  -14 ?   ?   ?   R . n 
E 5 40  GLN 40  -13 ?   ?   ?   R . n 
E 5 41  GLN 41  -12 ?   ?   ?   R . n 
E 5 42  ARG 42  -11 ?   ?   ?   R . n 
E 5 43  ASP 43  -10 ?   ?   ?   R . n 
E 5 44  GLU 44  -9  ?   ?   ?   R . n 
E 5 45  GLU 45  -8  ?   ?   ?   R . n 
E 5 46  ASN 46  -7  ?   ?   ?   R . n 
E 5 47  LEU 47  -6  ?   ?   ?   R . n 
E 5 48  TYR 48  -5  ?   ?   ?   R . n 
E 5 49  PHE 49  -4  ?   ?   ?   R . n 
E 5 50  GLN 50  -3  ?   ?   ?   R . n 
E 5 51  GLY 51  -2  ?   ?   ?   R . n 
E 5 52  VAL 52  -1  ?   ?   ?   R . n 
E 5 53  ASP 53  0   ?   ?   ?   R . n 
E 5 54  MET 54  1   ?   ?   ?   R . n 
E 5 55  SER 55  2   ?   ?   ?   R . n 
E 5 56  VAL 56  3   ?   ?   ?   R . n 
E 5 57  GLY 57  4   ?   ?   ?   R . n 
E 5 58  ALA 58  5   ?   ?   ?   R . n 
E 5 59  MET 59  6   ?   ?   ?   R . n 
E 5 60  LYS 60  7   ?   ?   ?   R . n 
E 5 61  LYS 61  8   ?   ?   ?   R . n 
E 5 62  GLY 62  9   ?   ?   ?   R . n 
E 5 63  VAL 63  10  ?   ?   ?   R . n 
E 5 64  GLY 64  11  ?   ?   ?   R . n 
E 5 65  ARG 65  12  ?   ?   ?   R . n 
E 5 66  ALA 66  13  ?   ?   ?   R . n 
E 5 67  VAL 67  14  ?   ?   ?   R . n 
E 5 68  GLY 68  15  ?   ?   ?   R . n 
E 5 69  LEU 69  16  ?   ?   ?   R . n 
E 5 70  GLY 70  17  ?   ?   ?   R . n 
E 5 71  GLY 71  18  ?   ?   ?   R . n 
E 5 72  GLY 72  19  ?   ?   ?   R . n 
E 5 73  SER 73  20  ?   ?   ?   R . n 
E 5 74  GLY 74  21  ?   ?   ?   R . n 
E 5 75  CYS 75  22  ?   ?   ?   R . n 
E 5 76  GLN 76  23  ?   ?   ?   R . n 
E 5 77  ALA 77  24  ?   ?   ?   R . n 
E 5 78  THR 78  25  ?   ?   ?   R . n 
E 5 79  GLU 79  26  ?   ?   ?   R . n 
E 5 80  GLU 80  27  ?   ?   ?   R . n 
E 5 81  ASP 81  28  ?   ?   ?   R . n 
E 5 82  PRO 82  29  ?   ?   ?   R . n 
E 5 83  LEU 83  30  ?   ?   ?   R . n 
E 5 84  PRO 84  31  ?   ?   ?   R . n 
E 5 85  ASN 85  32  ?   ?   ?   R . n 
E 5 86  CYS 86  33  ?   ?   ?   R . n 
E 5 87  GLY 87  34  ?   ?   ?   R . n 
E 5 88  ALA 88  35  ?   ?   ?   R . n 
E 5 89  CYS 89  36  ?   ?   ?   R . n 
E 5 90  ALA 90  37  ?   ?   ?   R . n 
E 5 91  PRO 91  38  ?   ?   ?   R . n 
E 5 92  GLY 92  39  ?   ?   ?   R . n 
E 5 93  GLN 93  40  ?   ?   ?   R . n 
E 5 94  GLY 94  41  ?   ?   ?   R . n 
E 5 95  GLY 95  42  ?   ?   ?   R . n 
E 5 96  ARG 96  43  ?   ?   ?   R . n 
E 5 97  ARG 97  44  ?   ?   ?   R . n 
E 5 98  TRP 98  45  ?   ?   ?   R . n 
E 5 99  ARG 99  46  ?   ?   ?   R . n 
E 5 100 LEU 100 47  ?   ?   ?   R . n 
E 5 101 PRO 101 48  ?   ?   ?   R . n 
E 5 102 GLN 102 49  ?   ?   ?   R . n 
E 5 103 PRO 103 50  ?   ?   ?   R . n 
E 5 104 ALA 104 51  ?   ?   ?   R . n 
E 5 105 TRP 105 52  ?   ?   ?   R . n 
E 5 106 VAL 106 53  ?   ?   ?   R . n 
E 5 107 GLU 107 54  ?   ?   ?   R . n 
E 5 108 GLY 108 55  ?   ?   ?   R . n 
E 5 109 SER 109 56  ?   ?   ?   R . n 
E 5 110 SER 110 57  ?   ?   ?   R . n 
E 5 111 ALA 111 58  ?   ?   ?   R . n 
E 5 112 ARG 112 59  ?   ?   ?   R . n 
E 5 113 LEU 113 60  ?   ?   ?   R . n 
E 5 114 TRP 114 61  ?   ?   ?   R . n 
E 5 115 GLU 115 62  ?   ?   ?   R . n 
E 5 116 GLN 116 63  ?   ?   ?   R . n 
E 5 117 ALA 117 64  ?   ?   ?   R . n 
E 5 118 THR 118 65  ?   ?   ?   R . n 
E 5 119 GLY 119 66  ?   ?   ?   R . n 
E 5 120 THR 120 67  ?   ?   ?   R . n 
E 5 121 GLY 121 68  ?   ?   ?   R . n 
E 5 122 TRP 122 69  ?   ?   ?   R . n 
E 5 123 MET 123 70  ?   ?   ?   R . n 
E 5 124 ASP 124 71  ?   ?   ?   R . n 
E 5 125 LEU 125 72  ?   ?   ?   R . n 
E 5 126 GLU 126 73  ?   ?   ?   R . n 
E 5 127 ALA 127 74  ?   ?   ?   R . n 
E 5 128 SER 128 75  ?   ?   ?   R . n 
E 5 129 LEU 129 76  ?   ?   ?   R . n 
E 5 130 LEU 130 77  ?   ?   ?   R . n 
E 5 131 PRO 131 78  ?   ?   ?   R . n 
E 5 132 THR 132 79  ?   ?   ?   R . n 
E 5 133 GLY 133 80  ?   ?   ?   R . n 
E 5 134 PRO 134 81  ?   ?   ?   R . n 
E 5 135 ASN 135 82  ?   ?   ?   R . n 
E 5 136 ALA 136 83  ?   ?   ?   R . n 
E 5 137 SER 137 84  ?   ?   ?   R . n 
E 5 138 ASN 138 85  ?   ?   ?   R . n 
E 5 139 THR 139 86  ?   ?   ?   R . n 
E 5 140 SER 140 87  ?   ?   ?   R . n 
E 5 141 ASP 141 88  ?   ?   ?   R . n 
E 5 142 GLY 142 89  ?   ?   ?   R . n 
E 5 143 PRO 143 90  ?   ?   ?   R . n 
E 5 144 ASP 144 91  ?   ?   ?   R . n 
E 5 145 ASN 145 92  ?   ?   ?   R . n 
E 5 146 LEU 146 93  ?   ?   ?   R . n 
E 5 147 THR 147 94  ?   ?   ?   R . n 
E 5 148 SER 148 95  ?   ?   ?   R . n 
E 5 149 ALA 149 96  ?   ?   ?   R . n 
E 5 150 GLY 150 97  ?   ?   ?   R . n 
E 5 151 SER 151 98  ?   ?   ?   R . n 
E 5 152 PRO 152 99  ?   ?   ?   R . n 
E 5 153 PRO 153 100 ?   ?   ?   R . n 
E 5 154 ARG 154 101 ?   ?   ?   R . n 
E 5 155 THR 155 102 ?   ?   ?   R . n 
E 5 156 GLY 156 103 ?   ?   ?   R . n 
E 5 157 SER 157 104 ?   ?   ?   R . n 
E 5 158 ILE 158 105 ?   ?   ?   R . n 
E 5 159 SER 159 106 ?   ?   ?   R . n 
E 5 160 TYR 160 107 107 TYR TYR R . n 
E 5 161 ILE 161 108 108 ILE ILE R . n 
E 5 162 ASN 162 109 109 ASN ASN R . n 
E 5 163 ILE 163 110 110 ILE ILE R . n 
E 5 164 ILE 164 111 111 ILE ILE R . n 
E 5 165 MET 165 112 112 MET MET R . n 
E 5 166 PRO 166 113 113 PRO PRO R . n 
E 5 167 SER 167 114 114 SER SER R . n 
E 5 168 VAL 168 115 115 VAL VAL R . n 
E 5 169 PHE 169 116 116 PHE PHE R . n 
E 5 170 GLY 170 117 117 GLY GLY R . n 
E 5 171 THR 171 118 118 THR THR R . n 
E 5 172 ILE 172 119 119 ILE ILE R . n 
E 5 173 CYS 173 120 120 CYS CYS R . n 
E 5 174 LEU 174 121 121 LEU LEU R . n 
E 5 175 LEU 175 122 122 LEU LEU R . n 
E 5 176 GLY 176 123 123 GLY GLY R . n 
E 5 177 ILE 177 124 124 ILE ILE R . n 
E 5 178 ILE 178 125 125 ILE ILE R . n 
E 5 179 GLY 179 126 126 GLY GLY R . n 
E 5 180 ASN 180 127 127 ASN ASN R . n 
E 5 181 SER 181 128 128 SER SER R . n 
E 5 182 THR 182 129 129 THR THR R . n 
E 5 183 VAL 183 130 130 VAL VAL R . n 
E 5 184 ILE 184 131 131 ILE ILE R . n 
E 5 185 PHE 185 132 132 PHE PHE R . n 
E 5 186 ALA 186 133 133 ALA ALA R . n 
E 5 187 VAL 187 134 134 VAL VAL R . n 
E 5 188 VAL 188 135 135 VAL VAL R . n 
E 5 189 LYS 189 136 136 LYS LYS R . n 
E 5 190 LYS 190 137 137 LYS LYS R . n 
E 5 191 SER 191 138 138 SER SER R . n 
E 5 192 LYS 192 139 139 LYS LYS R . n 
E 5 193 LEU 193 140 140 LEU LEU R . n 
E 5 194 HIS 194 141 141 HIS HIS R . n 
E 5 195 TRP 195 142 142 TRP TRP R . n 
E 5 196 CYS 196 143 143 CYS CYS R . n 
E 5 197 ASN 197 144 144 ASN ASN R . n 
E 5 198 ASN 198 145 145 ASN ASN R . n 
E 5 199 VAL 199 146 146 VAL VAL R . n 
E 5 200 PRO 200 147 147 PRO PRO R . n 
E 5 201 ASP 201 148 148 ASP ASP R . n 
E 5 202 ILE 202 149 149 ILE ILE R . n 
E 5 203 PHE 203 150 150 PHE PHE R . n 
E 5 204 ILE 204 151 151 ILE ILE R . n 
E 5 205 ILE 205 152 152 ILE ILE R . n 
E 5 206 ASN 206 153 153 ASN ASN R . n 
E 5 207 LEU 207 154 154 LEU LEU R . n 
E 5 208 SER 208 155 155 SER SER R . n 
E 5 209 VAL 209 156 156 VAL VAL R . n 
E 5 210 VAL 210 157 157 VAL VAL R . n 
E 5 211 ASP 211 158 158 ASP ASP R . n 
E 5 212 LEU 212 159 159 LEU LEU R . n 
E 5 213 LEU 213 160 160 LEU LEU R . n 
E 5 214 PHE 214 161 161 PHE PHE R . n 
E 5 215 LEU 215 162 162 LEU LEU R . n 
E 5 216 LEU 216 163 163 LEU LEU R . n 
E 5 217 GLY 217 164 164 GLY GLY R . n 
E 5 218 MET 218 165 165 MET MET R . n 
E 5 219 PRO 219 166 166 PRO PRO R . n 
E 5 220 PHE 220 167 167 PHE PHE R . n 
E 5 221 MET 221 168 168 MET MET R . n 
E 5 222 ILE 222 169 169 ILE ILE R . n 
E 5 223 HIS 223 170 170 HIS HIS R . n 
E 5 224 GLN 224 171 171 GLN GLN R . n 
E 5 225 LEU 225 172 172 LEU LEU R . n 
E 5 226 MET 226 173 173 MET MET R . n 
E 5 227 GLY 227 174 174 GLY GLY R . n 
E 5 228 ASN 228 175 175 ASN ASN R . n 
E 5 229 GLY 229 176 176 GLY GLY R . n 
E 5 230 VAL 230 177 177 VAL VAL R . n 
E 5 231 TRP 231 178 178 TRP TRP R . n 
E 5 232 HIS 232 179 179 HIS HIS R . n 
E 5 233 PHE 233 180 180 PHE PHE R . n 
E 5 234 GLY 234 181 181 GLY GLY R . n 
E 5 235 GLU 235 182 182 GLU GLU R . n 
E 5 236 THR 236 183 183 THR THR R . n 
E 5 237 MET 237 184 184 MET MET R . n 
E 5 238 CYS 238 185 185 CYS CYS R . n 
E 5 239 THR 239 186 186 THR THR R . n 
E 5 240 LEU 240 187 187 LEU LEU R . n 
E 5 241 ILE 241 188 188 ILE ILE R . n 
E 5 242 THR 242 189 189 THR THR R . n 
E 5 243 ALA 243 190 190 ALA ALA R . n 
E 5 244 MET 244 191 191 MET MET R . n 
E 5 245 ASP 245 192 192 ASP ASP R . n 
E 5 246 ALA 246 193 193 ALA ALA R . n 
E 5 247 ASN 247 194 194 ASN ASN R . n 
E 5 248 SER 248 195 195 SER SER R . n 
E 5 249 GLN 249 196 196 GLN GLN R . n 
E 5 250 PHE 250 197 197 PHE PHE R . n 
E 5 251 THR 251 198 198 THR THR R . n 
E 5 252 SER 252 199 199 SER SER R . n 
E 5 253 THR 253 200 200 THR THR R . n 
E 5 254 TYR 254 201 201 TYR TYR R . n 
E 5 255 ILE 255 202 202 ILE ILE R . n 
E 5 256 LEU 256 203 203 LEU LEU R . n 
E 5 257 THR 257 204 204 THR THR R . n 
E 5 258 ALA 258 205 205 ALA ALA R . n 
E 5 259 MET 259 206 206 MET MET R . n 
E 5 260 ALA 260 207 207 ALA ALA R . n 
E 5 261 ILE 261 208 208 ILE ILE R . n 
E 5 262 ASP 262 209 209 ASP ASP R . n 
E 5 263 ARG 263 210 210 ARG ARG R . n 
E 5 264 TYR 264 211 211 TYR TYR R . n 
E 5 265 LEU 265 212 212 LEU LEU R . n 
E 5 266 ALA 266 213 213 ALA ALA R . n 
E 5 267 THR 267 214 214 THR THR R . n 
E 5 268 VAL 268 215 215 VAL VAL R . n 
E 5 269 HIS 269 216 216 HIS HIS R . n 
E 5 270 PRO 270 217 217 PRO PRO R . n 
E 5 271 ILE 271 218 218 ILE ILE R . n 
E 5 272 SER 272 219 219 SER SER R . n 
E 5 273 SER 273 220 220 SER SER R . n 
E 5 274 THR 274 221 221 THR THR R . n 
E 5 275 LYS 275 222 222 LYS LYS R . n 
E 5 276 PHE 276 223 223 PHE PHE R . n 
E 5 277 ARG 277 224 224 ARG ARG R . n 
E 5 278 LYS 278 225 225 LYS LYS R . n 
E 5 279 PRO 279 226 226 PRO PRO R . n 
E 5 280 SER 280 227 227 SER SER R . n 
E 5 281 VAL 281 228 228 VAL VAL R . n 
E 5 282 ALA 282 229 229 ALA ALA R . n 
E 5 283 THR 283 230 230 THR THR R . n 
E 5 284 LEU 284 231 231 LEU LEU R . n 
E 5 285 VAL 285 232 232 VAL VAL R . n 
E 5 286 ILE 286 233 233 ILE ILE R . n 
E 5 287 CYS 287 234 234 CYS CYS R . n 
E 5 288 LEU 288 235 235 LEU LEU R . n 
E 5 289 LEU 289 236 236 LEU LEU R . n 
E 5 290 TRP 290 237 237 TRP TRP R . n 
E 5 291 ALA 291 238 238 ALA ALA R . n 
E 5 292 LEU 292 239 239 LEU LEU R . n 
E 5 293 SER 293 240 240 SER SER R . n 
E 5 294 PHE 294 241 241 PHE PHE R . n 
E 5 295 ILE 295 242 242 ILE ILE R . n 
E 5 296 SER 296 243 243 SER SER R . n 
E 5 297 ILE 297 244 244 ILE ILE R . n 
E 5 298 THR 298 245 245 THR THR R . n 
E 5 299 PRO 299 246 246 PRO PRO R . n 
E 5 300 VAL 300 247 247 VAL VAL R . n 
E 5 301 TRP 301 248 248 TRP TRP R . n 
E 5 302 LEU 302 249 249 LEU LEU R . n 
E 5 303 TYR 303 250 250 TYR TYR R . n 
E 5 304 ALA 304 251 251 ALA ALA R . n 
E 5 305 ARG 305 252 252 ARG ARG R . n 
E 5 306 LEU 306 253 253 LEU LEU R . n 
E 5 307 ILE 307 254 254 ILE ILE R . n 
E 5 308 PRO 308 255 255 PRO PRO R . n 
E 5 309 PHE 309 256 256 PHE PHE R . n 
E 5 310 PRO 310 257 257 PRO PRO R . n 
E 5 311 GLY 311 258 258 GLY GLY R . n 
E 5 312 GLY 312 259 259 GLY GLY R . n 
E 5 313 ALA 313 260 260 ALA ALA R . n 
E 5 314 VAL 314 261 261 VAL VAL R . n 
E 5 315 GLY 315 262 262 GLY GLY R . n 
E 5 316 CYS 316 263 263 CYS CYS R . n 
E 5 317 GLY 317 264 264 GLY GLY R . n 
E 5 318 ILE 318 265 265 ILE ILE R . n 
E 5 319 ARG 319 266 266 ARG ARG R . n 
E 5 320 LEU 320 267 267 LEU LEU R . n 
E 5 321 PRO 321 268 268 PRO PRO R . n 
E 5 322 ASN 322 269 269 ASN ASN R . n 
E 5 323 PRO 323 270 270 PRO PRO R . n 
E 5 324 ASP 324 271 271 ASP ASP R . n 
E 5 325 THR 325 272 272 THR THR R . n 
E 5 326 ASP 326 273 273 ASP ASP R . n 
E 5 327 LEU 327 274 274 LEU LEU R . n 
E 5 328 TYR 328 275 275 TYR TYR R . n 
E 5 329 TRP 329 276 276 TRP TRP R . n 
E 5 330 PHE 330 277 277 PHE PHE R . n 
E 5 331 THR 331 278 278 THR THR R . n 
E 5 332 LEU 332 279 279 LEU LEU R . n 
E 5 333 TYR 333 280 280 TYR TYR R . n 
E 5 334 GLN 334 281 281 GLN GLN R . n 
E 5 335 PHE 335 282 282 PHE PHE R . n 
E 5 336 PHE 336 283 283 PHE PHE R . n 
E 5 337 LEU 337 284 284 LEU LEU R . n 
E 5 338 ALA 338 285 285 ALA ALA R . n 
E 5 339 PHE 339 286 286 PHE PHE R . n 
E 5 340 ALA 340 287 287 ALA ALA R . n 
E 5 341 LEU 341 288 288 LEU LEU R . n 
E 5 342 PRO 342 289 289 PRO PRO R . n 
E 5 343 PHE 343 290 290 PHE PHE R . n 
E 5 344 VAL 344 291 291 VAL VAL R . n 
E 5 345 VAL 345 292 292 VAL VAL R . n 
E 5 346 ILE 346 293 293 ILE ILE R . n 
E 5 347 THR 347 294 294 THR THR R . n 
E 5 348 ALA 348 295 295 ALA ALA R . n 
E 5 349 ALA 349 296 296 ALA ALA R . n 
E 5 350 TYR 350 297 297 TYR TYR R . n 
E 5 351 VAL 351 298 298 VAL VAL R . n 
E 5 352 ARG 352 299 299 ARG ARG R . n 
E 5 353 ILE 353 300 300 ILE ILE R . n 
E 5 354 LEU 354 301 301 LEU LEU R . n 
E 5 355 GLN 355 302 302 GLN GLN R . n 
E 5 356 ARG 356 303 303 ARG ARG R . n 
E 5 357 MET 357 304 304 MET MET R . n 
E 5 358 THR 358 305 305 THR THR R . n 
E 5 359 SER 359 306 306 SER SER R . n 
E 5 360 SER 360 307 307 SER SER R . n 
E 5 361 VAL 361 308 308 VAL VAL R . n 
E 5 362 ALA 362 309 309 ALA ALA R . n 
E 5 363 PRO 363 310 310 PRO PRO R . n 
E 5 364 ALA 364 311 311 ALA ALA R . n 
E 5 365 SER 365 312 312 SER SER R . n 
E 5 366 GLN 366 313 313 GLN GLN R . n 
E 5 367 ARG 367 314 314 ARG ARG R . n 
E 5 368 SER 368 315 315 SER SER R . n 
E 5 369 ILE 369 316 316 ILE ILE R . n 
E 5 370 ARG 370 317 317 ARG ARG R . n 
E 5 371 LEU 371 318 318 LEU LEU R . n 
E 5 372 ARG 372 319 319 ARG ARG R . n 
E 5 373 THR 373 320 320 THR THR R . n 
E 5 374 LYS 374 321 321 LYS LYS R . n 
E 5 375 ARG 375 322 322 ARG ARG R . n 
E 5 376 VAL 376 323 323 VAL VAL R . n 
E 5 377 THR 377 324 324 THR THR R . n 
E 5 378 ARG 378 325 325 ARG ARG R . n 
E 5 379 THR 379 326 326 THR THR R . n 
E 5 380 ALA 380 327 327 ALA ALA R . n 
E 5 381 ILE 381 328 328 ILE ILE R . n 
E 5 382 ALA 382 329 329 ALA ALA R . n 
E 5 383 ILE 383 330 330 ILE ILE R . n 
E 5 384 CYS 384 331 331 CYS CYS R . n 
E 5 385 LEU 385 332 332 LEU LEU R . n 
E 5 386 VAL 386 333 333 VAL VAL R . n 
E 5 387 PHE 387 334 334 PHE PHE R . n 
E 5 388 PHE 388 335 335 PHE PHE R . n 
E 5 389 VAL 389 336 336 VAL VAL R . n 
E 5 390 CYS 390 337 337 CYS CYS R . n 
E 5 391 TRP 391 338 338 TRP TRP R . n 
E 5 392 ALA 392 339 339 ALA ALA R . n 
E 5 393 PRO 393 340 340 PRO PRO R . n 
E 5 394 TYR 394 341 341 TYR TYR R . n 
E 5 395 TYR 395 342 342 TYR TYR R . n 
E 5 396 VAL 396 343 343 VAL VAL R . n 
E 5 397 LEU 397 344 344 LEU LEU R . n 
E 5 398 GLN 398 345 345 GLN GLN R . n 
E 5 399 LEU 399 346 346 LEU LEU R . n 
E 5 400 THR 400 347 347 THR THR R . n 
E 5 401 GLN 401 348 348 GLN GLN R . n 
E 5 402 LEU 402 349 349 LEU LEU R . n 
E 5 403 SER 403 350 350 SER SER R . n 
E 5 404 ILE 404 351 351 ILE ILE R . n 
E 5 405 SER 405 352 352 SER SER R . n 
E 5 406 ARG 406 353 353 ARG ARG R . n 
E 5 407 PRO 407 354 354 PRO PRO R . n 
E 5 408 THR 408 355 355 THR THR R . n 
E 5 409 LEU 409 356 356 LEU LEU R . n 
E 5 410 THR 410 357 357 THR THR R . n 
E 5 411 PHE 411 358 358 PHE PHE R . n 
E 5 412 VAL 412 359 359 VAL VAL R . n 
E 5 413 TYR 413 360 360 TYR TYR R . n 
E 5 414 LEU 414 361 361 LEU LEU R . n 
E 5 415 TYR 415 362 362 TYR TYR R . n 
E 5 416 ASN 416 363 363 ASN ASN R . n 
E 5 417 ALA 417 364 364 ALA ALA R . n 
E 5 418 ALA 418 365 365 ALA ALA R . n 
E 5 419 ILE 419 366 366 ILE ILE R . n 
E 5 420 SER 420 367 367 SER SER R . n 
E 5 421 LEU 421 368 368 LEU LEU R . n 
E 5 422 GLY 422 369 369 GLY GLY R . n 
E 5 423 TYR 423 370 370 TYR TYR R . n 
E 5 424 ALA 424 371 371 ALA ALA R . n 
E 5 425 ASN 425 372 372 ASN ASN R . n 
E 5 426 SER 426 373 373 SER SER R . n 
E 5 427 CYS 427 374 374 CYS CYS R . n 
E 5 428 LEU 428 375 375 LEU LEU R . n 
E 5 429 ASN 429 376 376 ASN ASN R . n 
E 5 430 PRO 430 377 377 PRO PRO R . n 
E 5 431 PHE 431 378 378 PHE PHE R . n 
E 5 432 VAL 432 379 379 VAL VAL R . n 
E 5 433 TYR 433 380 380 TYR TYR R . n 
E 5 434 ILE 434 381 381 ILE ILE R . n 
E 5 435 VAL 435 382 382 VAL VAL R . n 
E 5 436 LEU 436 383 383 LEU LEU R . n 
E 5 437 CYS 437 384 384 CYS CYS R . n 
E 5 438 GLU 438 385 385 GLU GLU R . n 
E 5 439 THR 439 386 386 THR THR R . n 
E 5 440 PHE 440 387 387 PHE PHE R . n 
E 5 441 ARG 441 388 388 ARG ARG R . n 
E 5 442 LYS 442 389 389 LYS LYS R . n 
E 5 443 ARG 443 390 390 ARG ARG R . n 
E 5 444 LEU 444 391 391 LEU LEU R . n 
E 5 445 VAL 445 392 392 VAL VAL R . n 
E 5 446 LEU 446 393 393 LEU LEU R . n 
E 5 447 SER 447 394 394 SER SER R . n 
E 5 448 VAL 448 395 395 VAL VAL R . n 
E 5 449 LYS 449 396 ?   ?   ?   R . n 
E 5 450 HIS 450 397 ?   ?   ?   R . n 
E 5 451 MET 451 398 ?   ?   ?   R . n 
E 5 452 GLY 452 399 ?   ?   ?   R . n 
E 5 453 SER 453 400 ?   ?   ?   R . n 
E 5 454 SER 454 401 ?   ?   ?   R . n 
E 5 455 GLY 455 402 ?   ?   ?   R . n 
E 5 456 GLY 456 403 ?   ?   ?   R . n 
E 5 457 GLY 457 404 ?   ?   ?   R . n 
E 5 458 GLY 458 405 ?   ?   ?   R . n 
E 5 459 SER 459 406 ?   ?   ?   R . n 
E 5 460 GLY 460 407 ?   ?   ?   R . n 
E 5 461 GLY 461 408 ?   ?   ?   R . n 
E 5 462 GLY 462 409 ?   ?   ?   R . n 
E 5 463 GLY 463 410 ?   ?   ?   R . n 
E 5 464 SER 464 411 ?   ?   ?   R . n 
E 5 465 SER 465 412 ?   ?   ?   R . n 
E 5 466 GLY 466 413 ?   ?   ?   R . n 
E 5 467 VAL 467 414 ?   ?   ?   R . n 
E 5 468 PHE 468 415 ?   ?   ?   R . n 
E 5 469 THR 469 416 ?   ?   ?   R . n 
E 5 470 LEU 470 417 ?   ?   ?   R . n 
E 5 471 GLU 471 418 ?   ?   ?   R . n 
E 5 472 ASP 472 419 ?   ?   ?   R . n 
E 5 473 PHE 473 420 ?   ?   ?   R . n 
E 5 474 VAL 474 421 ?   ?   ?   R . n 
E 5 475 GLY 475 422 ?   ?   ?   R . n 
E 5 476 ASP 476 423 ?   ?   ?   R . n 
E 5 477 TRP 477 424 ?   ?   ?   R . n 
E 5 478 GLU 478 425 ?   ?   ?   R . n 
E 5 479 GLN 479 426 ?   ?   ?   R . n 
E 5 480 THR 480 427 ?   ?   ?   R . n 
E 5 481 ALA 481 428 ?   ?   ?   R . n 
E 5 482 ALA 482 429 ?   ?   ?   R . n 
E 5 483 TYR 483 430 ?   ?   ?   R . n 
E 5 484 ASN 484 431 ?   ?   ?   R . n 
E 5 485 LEU 485 432 ?   ?   ?   R . n 
E 5 486 ASP 486 433 ?   ?   ?   R . n 
E 5 487 GLN 487 434 ?   ?   ?   R . n 
E 5 488 VAL 488 435 ?   ?   ?   R . n 
E 5 489 LEU 489 436 ?   ?   ?   R . n 
E 5 490 GLU 490 437 ?   ?   ?   R . n 
E 5 491 GLN 491 438 ?   ?   ?   R . n 
E 5 492 GLY 492 439 ?   ?   ?   R . n 
E 5 493 GLY 493 440 ?   ?   ?   R . n 
E 5 494 VAL 494 441 ?   ?   ?   R . n 
E 5 495 SER 495 442 ?   ?   ?   R . n 
E 5 496 SER 496 443 ?   ?   ?   R . n 
E 5 497 LEU 497 444 ?   ?   ?   R . n 
E 5 498 LEU 498 445 ?   ?   ?   R . n 
E 5 499 GLN 499 446 ?   ?   ?   R . n 
E 5 500 ASN 500 447 ?   ?   ?   R . n 
E 5 501 LEU 501 448 ?   ?   ?   R . n 
E 5 502 ALA 502 449 ?   ?   ?   R . n 
E 5 503 VAL 503 450 ?   ?   ?   R . n 
E 5 504 SER 504 451 ?   ?   ?   R . n 
E 5 505 VAL 505 452 ?   ?   ?   R . n 
E 5 506 THR 506 453 ?   ?   ?   R . n 
E 5 507 PRO 507 454 ?   ?   ?   R . n 
E 5 508 ILE 508 455 ?   ?   ?   R . n 
E 5 509 GLN 509 456 ?   ?   ?   R . n 
E 5 510 ARG 510 457 ?   ?   ?   R . n 
E 5 511 ILE 511 458 ?   ?   ?   R . n 
E 5 512 VAL 512 459 ?   ?   ?   R . n 
E 5 513 ARG 513 460 ?   ?   ?   R . n 
E 5 514 SER 514 461 ?   ?   ?   R . n 
E 5 515 GLY 515 462 ?   ?   ?   R . n 
E 5 516 GLU 516 463 ?   ?   ?   R . n 
E 5 517 ASN 517 464 ?   ?   ?   R . n 
E 5 518 ALA 518 465 ?   ?   ?   R . n 
E 5 519 LEU 519 466 ?   ?   ?   R . n 
E 5 520 LYS 520 467 ?   ?   ?   R . n 
E 5 521 ILE 521 468 ?   ?   ?   R . n 
E 5 522 ASP 522 469 ?   ?   ?   R . n 
E 5 523 ILE 523 470 ?   ?   ?   R . n 
E 5 524 HIS 524 471 ?   ?   ?   R . n 
E 5 525 VAL 525 472 ?   ?   ?   R . n 
E 5 526 ILE 526 473 ?   ?   ?   R . n 
E 5 527 ILE 527 474 ?   ?   ?   R . n 
E 5 528 PRO 528 475 ?   ?   ?   R . n 
E 5 529 TYR 529 476 ?   ?   ?   R . n 
E 5 530 GLU 530 477 ?   ?   ?   R . n 
E 5 531 GLY 531 478 ?   ?   ?   R . n 
E 5 532 LEU 532 479 ?   ?   ?   R . n 
E 5 533 SER 533 480 ?   ?   ?   R . n 
E 5 534 ALA 534 481 ?   ?   ?   R . n 
E 5 535 ASP 535 482 ?   ?   ?   R . n 
E 5 536 GLN 536 483 ?   ?   ?   R . n 
E 5 537 MET 537 484 ?   ?   ?   R . n 
E 5 538 ALA 538 485 ?   ?   ?   R . n 
E 5 539 GLN 539 486 ?   ?   ?   R . n 
E 5 540 ILE 540 487 ?   ?   ?   R . n 
E 5 541 GLU 541 488 ?   ?   ?   R . n 
E 5 542 GLU 542 489 ?   ?   ?   R . n 
E 5 543 VAL 543 490 ?   ?   ?   R . n 
E 5 544 PHE 544 491 ?   ?   ?   R . n 
E 5 545 LYS 545 492 ?   ?   ?   R . n 
E 5 546 VAL 546 493 ?   ?   ?   R . n 
E 5 547 VAL 547 494 ?   ?   ?   R . n 
E 5 548 TYR 548 495 ?   ?   ?   R . n 
E 5 549 PRO 549 496 ?   ?   ?   R . n 
E 5 550 VAL 550 497 ?   ?   ?   R . n 
E 5 551 ASP 551 498 ?   ?   ?   R . n 
E 5 552 ASP 552 499 ?   ?   ?   R . n 
E 5 553 HIS 553 500 ?   ?   ?   R . n 
E 5 554 HIS 554 501 ?   ?   ?   R . n 
E 5 555 PHE 555 502 ?   ?   ?   R . n 
E 5 556 LYS 556 503 ?   ?   ?   R . n 
E 5 557 VAL 557 504 ?   ?   ?   R . n 
E 5 558 ILE 558 505 ?   ?   ?   R . n 
E 5 559 LEU 559 506 ?   ?   ?   R . n 
E 5 560 PRO 560 507 ?   ?   ?   R . n 
E 5 561 TYR 561 508 ?   ?   ?   R . n 
E 5 562 GLY 562 509 ?   ?   ?   R . n 
E 5 563 THR 563 510 ?   ?   ?   R . n 
E 5 564 LEU 564 511 ?   ?   ?   R . n 
E 5 565 VAL 565 512 ?   ?   ?   R . n 
E 5 566 ILE 566 513 ?   ?   ?   R . n 
E 5 567 ASP 567 514 ?   ?   ?   R . n 
E 5 568 GLY 568 515 ?   ?   ?   R . n 
E 5 569 VAL 569 516 ?   ?   ?   R . n 
E 5 570 THR 570 517 ?   ?   ?   R . n 
E 5 571 PRO 571 518 ?   ?   ?   R . n 
E 5 572 ASN 572 519 ?   ?   ?   R . n 
E 5 573 MET 573 520 ?   ?   ?   R . n 
E 5 574 LEU 574 521 ?   ?   ?   R . n 
E 5 575 ASN 575 522 ?   ?   ?   R . n 
E 5 576 TYR 576 523 ?   ?   ?   R . n 
E 5 577 PHE 577 524 ?   ?   ?   R . n 
E 5 578 GLY 578 525 ?   ?   ?   R . n 
E 5 579 ARG 579 526 ?   ?   ?   R . n 
E 5 580 PRO 580 527 ?   ?   ?   R . n 
E 5 581 TYR 581 528 ?   ?   ?   R . n 
E 5 582 GLU 582 529 ?   ?   ?   R . n 
E 5 583 GLY 583 530 ?   ?   ?   R . n 
E 5 584 ILE 584 531 ?   ?   ?   R . n 
E 5 585 ALA 585 532 ?   ?   ?   R . n 
E 5 586 VAL 586 533 ?   ?   ?   R . n 
E 5 587 PHE 587 534 ?   ?   ?   R . n 
E 5 588 ASP 588 535 ?   ?   ?   R . n 
E 5 589 GLY 589 536 ?   ?   ?   R . n 
E 5 590 LYS 590 537 ?   ?   ?   R . n 
E 5 591 LYS 591 538 ?   ?   ?   R . n 
E 5 592 ILE 592 539 ?   ?   ?   R . n 
E 5 593 THR 593 540 ?   ?   ?   R . n 
E 5 594 VAL 594 541 ?   ?   ?   R . n 
E 5 595 THR 595 542 ?   ?   ?   R . n 
E 5 596 GLY 596 543 ?   ?   ?   R . n 
E 5 597 THR 597 544 ?   ?   ?   R . n 
E 5 598 LEU 598 545 ?   ?   ?   R . n 
E 5 599 TRP 599 546 ?   ?   ?   R . n 
E 5 600 ASN 600 547 ?   ?   ?   R . n 
E 5 601 GLY 601 548 ?   ?   ?   R . n 
E 5 602 ASN 602 549 ?   ?   ?   R . n 
E 5 603 LYS 603 550 ?   ?   ?   R . n 
E 5 604 ILE 604 551 ?   ?   ?   R . n 
E 5 605 ILE 605 552 ?   ?   ?   R . n 
E 5 606 ASP 606 553 ?   ?   ?   R . n 
E 5 607 GLU 607 554 ?   ?   ?   R . n 
E 5 608 ARG 608 555 ?   ?   ?   R . n 
E 5 609 LEU 609 556 ?   ?   ?   R . n 
E 5 610 ILE 610 557 ?   ?   ?   R . n 
E 5 611 THR 611 558 ?   ?   ?   R . n 
E 5 612 PRO 612 559 ?   ?   ?   R . n 
E 5 613 ASP 613 560 ?   ?   ?   R . n 
E 5 614 GLY 614 561 ?   ?   ?   R . n 
E 5 615 SER 615 562 ?   ?   ?   R . n 
E 5 616 MET 616 563 ?   ?   ?   R . n 
E 5 617 LEU 617 564 ?   ?   ?   R . n 
E 5 618 PHE 618 565 ?   ?   ?   R . n 
E 5 619 ARG 619 566 ?   ?   ?   R . n 
E 5 620 VAL 620 567 ?   ?   ?   R . n 
E 5 621 THR 621 568 ?   ?   ?   R . n 
E 5 622 ILE 622 569 ?   ?   ?   R . n 
E 5 623 ASN 623 570 ?   ?   ?   R . n 
E 5 624 SER 624 571 ?   ?   ?   R . n 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 A GLU 43  ? CG  ? A GLU 43  CG  
2   1 Y 1 A GLU 43  ? CD  ? A GLU 43  CD  
3   1 Y 1 A GLU 43  ? OE1 ? A GLU 43  OE1 
4   1 Y 1 A GLU 43  ? OE2 ? A GLU 43  OE2 
5   1 Y 1 A THR 48  ? OG1 ? A THR 48  OG1 
6   1 Y 1 A THR 48  ? CG2 ? A THR 48  CG2 
7   1 Y 1 A LYS 51  ? CG  ? A LYS 51  CG  
8   1 Y 1 A LYS 51  ? CD  ? A LYS 51  CD  
9   1 Y 1 A LYS 51  ? CE  ? A LYS 51  CE  
10  1 Y 1 A LYS 51  ? NZ  ? A LYS 51  NZ  
11  1 Y 1 A LYS 54  ? CG  ? A LYS 54  CG  
12  1 Y 1 A LYS 54  ? CD  ? A LYS 54  CD  
13  1 Y 1 A LYS 54  ? CE  ? A LYS 54  CE  
14  1 Y 1 A LYS 54  ? NZ  ? A LYS 54  NZ  
15  1 Y 1 A THR 182 ? OG1 ? A THR 182 OG1 
16  1 Y 1 A THR 182 ? CG2 ? A THR 182 CG2 
17  1 Y 1 A ARG 205 ? CG  ? A ARG 205 CG  
18  1 Y 1 A ARG 205 ? CD  ? A ARG 205 CD  
19  1 Y 1 A ARG 205 ? NE  ? A ARG 205 NE  
20  1 Y 1 A ARG 205 ? CZ  ? A ARG 205 CZ  
21  1 Y 1 A ARG 205 ? NH1 ? A ARG 205 NH1 
22  1 Y 1 A ARG 205 ? NH2 ? A ARG 205 NH2 
23  1 Y 1 A GLU 236 ? CG  ? A GLU 236 CG  
24  1 Y 1 A GLU 236 ? CD  ? A GLU 236 CD  
25  1 Y 1 A GLU 236 ? OE1 ? A GLU 236 OE1 
26  1 Y 1 A GLU 236 ? OE2 ? A GLU 236 OE2 
27  1 Y 1 A ASP 237 ? CG  ? A ASP 237 CG  
28  1 Y 1 A ASP 237 ? OD1 ? A ASP 237 OD1 
29  1 Y 1 A ASP 237 ? OD2 ? A ASP 237 OD2 
30  1 Y 1 A GLU 238 ? CG  ? A GLU 238 CG  
31  1 Y 1 A GLU 238 ? CD  ? A GLU 238 CD  
32  1 Y 1 A GLU 238 ? OE1 ? A GLU 238 OE1 
33  1 Y 1 A GLU 238 ? OE2 ? A GLU 238 OE2 
34  1 Y 1 A GLU 239 ? CG  ? A GLU 239 CG  
35  1 Y 1 A GLU 239 ? CD  ? A GLU 239 CD  
36  1 Y 1 A GLU 239 ? OE1 ? A GLU 239 OE1 
37  1 Y 1 A GLU 239 ? OE2 ? A GLU 239 OE2 
38  1 Y 1 A LYS 248 ? CG  ? A LYS 248 CG  
39  1 Y 1 A LYS 248 ? CD  ? A LYS 248 CD  
40  1 Y 1 A LYS 248 ? CE  ? A LYS 248 CE  
41  1 Y 1 A LYS 248 ? NZ  ? A LYS 248 NZ  
42  1 Y 1 A LYS 279 ? CG  ? A LYS 279 CG  
43  1 Y 1 A LYS 279 ? CD  ? A LYS 279 CD  
44  1 Y 1 A LYS 279 ? CE  ? A LYS 279 CE  
45  1 Y 1 A LYS 279 ? NZ  ? A LYS 279 NZ  
46  1 Y 1 A LYS 280 ? CG  ? A LYS 280 CG  
47  1 Y 1 A LYS 280 ? CD  ? A LYS 280 CD  
48  1 Y 1 A LYS 280 ? CE  ? A LYS 280 CE  
49  1 Y 1 A LYS 280 ? NZ  ? A LYS 280 NZ  
50  1 Y 1 A GLU 289 ? CG  ? A GLU 289 CG  
51  1 Y 1 A GLU 289 ? CD  ? A GLU 289 CD  
52  1 Y 1 A GLU 289 ? OE1 ? A GLU 289 OE1 
53  1 Y 1 A GLU 289 ? OE2 ? A GLU 289 OE2 
54  1 Y 1 A GLU 298 ? CG  ? A GLU 298 CG  
55  1 Y 1 A GLU 298 ? CD  ? A GLU 298 CD  
56  1 Y 1 A GLU 298 ? OE1 ? A GLU 298 OE1 
57  1 Y 1 A GLU 298 ? OE2 ? A GLU 298 OE2 
58  1 Y 1 R TYR 107 ? CG  ? E TYR 160 CG  
59  1 Y 1 R TYR 107 ? CD1 ? E TYR 160 CD1 
60  1 Y 1 R TYR 107 ? CD2 ? E TYR 160 CD2 
61  1 Y 1 R TYR 107 ? CE1 ? E TYR 160 CE1 
62  1 Y 1 R TYR 107 ? CE2 ? E TYR 160 CE2 
63  1 Y 1 R TYR 107 ? CZ  ? E TYR 160 CZ  
64  1 Y 1 R TYR 107 ? OH  ? E TYR 160 OH  
65  1 Y 1 R ILE 108 ? CG1 ? E ILE 161 CG1 
66  1 Y 1 R ILE 108 ? CG2 ? E ILE 161 CG2 
67  1 Y 1 R ILE 108 ? CD1 ? E ILE 161 CD1 
68  1 Y 1 R ASN 109 ? CG  ? E ASN 162 CG  
69  1 Y 1 R ASN 109 ? OD1 ? E ASN 162 OD1 
70  1 Y 1 R ASN 109 ? ND2 ? E ASN 162 ND2 
71  1 Y 1 R ILE 110 ? CG1 ? E ILE 163 CG1 
72  1 Y 1 R ILE 110 ? CG2 ? E ILE 163 CG2 
73  1 Y 1 R ILE 110 ? CD1 ? E ILE 163 CD1 
74  1 Y 1 R ILE 111 ? CG1 ? E ILE 164 CG1 
75  1 Y 1 R ILE 111 ? CG2 ? E ILE 164 CG2 
76  1 Y 1 R ILE 111 ? CD1 ? E ILE 164 CD1 
77  1 Y 1 R LYS 136 ? CG  ? E LYS 189 CG  
78  1 Y 1 R LYS 136 ? CD  ? E LYS 189 CD  
79  1 Y 1 R LYS 136 ? CE  ? E LYS 189 CE  
80  1 Y 1 R LYS 136 ? NZ  ? E LYS 189 NZ  
81  1 Y 1 R ASN 175 ? CG  ? E ASN 228 CG  
82  1 Y 1 R ASN 175 ? OD1 ? E ASN 228 OD1 
83  1 Y 1 R ASN 175 ? ND2 ? E ASN 228 ND2 
84  1 Y 1 R ARG 314 ? CG  ? E ARG 367 CG  
85  1 Y 1 R ARG 314 ? CD  ? E ARG 367 CD  
86  1 Y 1 R ARG 314 ? NE  ? E ARG 367 NE  
87  1 Y 1 R ARG 314 ? CZ  ? E ARG 367 CZ  
88  1 Y 1 R ARG 314 ? NH1 ? E ARG 367 NH1 
89  1 Y 1 R ARG 314 ? NH2 ? E ARG 367 NH2 
90  1 Y 1 R ARG 317 ? CG  ? E ARG 370 CG  
91  1 Y 1 R ARG 317 ? CD  ? E ARG 370 CD  
92  1 Y 1 R ARG 317 ? NE  ? E ARG 370 NE  
93  1 Y 1 R ARG 317 ? CZ  ? E ARG 370 CZ  
94  1 Y 1 R ARG 317 ? NH1 ? E ARG 370 NH1 
95  1 Y 1 R ARG 317 ? NH2 ? E ARG 370 NH2 
96  1 Y 1 R ARG 353 ? CG  ? E ARG 406 CG  
97  1 Y 1 R ARG 353 ? CD  ? E ARG 406 CD  
98  1 Y 1 R ARG 353 ? NE  ? E ARG 406 NE  
99  1 Y 1 R ARG 353 ? CZ  ? E ARG 406 CZ  
100 1 Y 1 R ARG 353 ? NH1 ? E ARG 406 NH1 
101 1 Y 1 R ARG 353 ? NH2 ? E ARG 406 NH2 
102 1 Y 1 R GLU 385 ? CG  ? E GLU 438 CG  
103 1 Y 1 R GLU 385 ? CD  ? E GLU 438 CD  
104 1 Y 1 R GLU 385 ? OE1 ? E GLU 438 OE1 
105 1 Y 1 R GLU 385 ? OE2 ? E GLU 438 OE2 
106 1 Y 1 R LYS 389 ? CG  ? E LYS 442 CG  
107 1 Y 1 R LYS 389 ? CD  ? E LYS 442 CD  
108 1 Y 1 R LYS 389 ? CE  ? E LYS 442 CE  
109 1 Y 1 R LYS 389 ? NZ  ? E LYS 442 NZ  
110 1 Y 1 R LEU 393 ? CG  ? E LEU 446 CG  
111 1 Y 1 R LEU 393 ? CD1 ? E LEU 446 CD1 
112 1 Y 1 R LEU 393 ? CD2 ? E LEU 446 CD2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8WWH 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8WWH 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8WWH 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 8WWH 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.003 ? 9010  ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.419 ? 12233 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 8.125 ? 3182  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.041 ? 1406  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.003 ? 1547  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8WWH 
_struct.title                        'MCHR1-Gi complex,S1 state' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8WWH 
_struct_keywords.text            'Apo complex GPCR MCHR1, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP GNAI1_HUMAN P63096 ? 1 
;MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAGYSEEECKQYKAVVYSNTIQS
IIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLD
RIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM
NRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIY
THFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF
;
1   
2 UNP GBB1_HUMAN  P62873 ? 2 
;SELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLII
WDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSS
GDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAF
ATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVT
DDGMAVATGSWDSFLKIWN
;
2   
3 UNP GBG2_HUMAN  P59768 ? 3 MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL 1   
4 PDB 8WWH        8WWH   ? 4 ? 1   
5 PDB 8WWH        8WWH   ? 5 ? 1   
6 UNP MCHR1_HUMAN Q99705 ? 5 
;MSVGAMKKGVGRAVGLGGGSGCQATEEDPLPNCGACAPGQGGRRWRLPQPAWVEGSSARLWEQATGTGWMDLEASLLPTG
PNASNTSDGPDNLTSAGSPPRTGSISYINIIMPSVFGTICLLGIIGNSTVIFAVVKKSKLHWCNNVPDIFIINLSVVDLL
FLLGMPFMIHQLMGNGVWHFGETMCTLITAMDANSQFTSTYILTAMAIDRYLATVHPISSTKFRKPSVATLVICLLWALS
FISITPVWLYARLIPFPGGAVGCGIRLPNPDTDLYWFTLYQFFLAFALPFVVITAAYVRILQRMTSSVAPASQRSIRLRT
KRVTRTAIAICLVFFVCWAPYYVLQLTQLSISRPTLTFVYLYNAAISLGYANSCLNPFVYIVLCETFRKRLVLSVK
;
1   
7 PDB 8WWH        8WWH   ? 5 ? 450 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8WWH A 1   ? 354 ? P63096 1   ? 354 ? 1   354 
2 2 8WWH B 12  ? 350 ? P62873 2   ? 340 ? 2   340 
3 3 8WWH C 1   ? 71  ? P59768 1   ? 71  ? 1   71  
4 4 8WWH E 1   ? 255 ? 8WWH   1   ? 255 ? 1   255 
5 5 8WWH R 1   ? 53  ? 8WWH   -52 ? 0   ? -52 0   
6 6 8WWH R 54  ? 449 ? Q99705 1   ? 396 ? 1   396 
7 7 8WWH R 450 ? 624 ? 8WWH   397 ? 571 ? 397 571 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8WWH ASN A 47  ? UNP P63096 SER 47  conflict                47  1  
1 8WWH ALA A 203 ? UNP P63096 GLY 203 conflict                203 2  
1 8WWH ALA A 245 ? UNP P63096 GLU 245 conflict                245 3  
1 8WWH SER A 326 ? UNP P63096 ALA 326 conflict                326 4  
2 8WWH MET B 1   ? UNP P62873 ?   ?   'initiating methionine' -9  5  
2 8WWH HIS B 2   ? UNP P62873 ?   ?   'expression tag'        -8  6  
2 8WWH HIS B 3   ? UNP P62873 ?   ?   'expression tag'        -7  7  
2 8WWH HIS B 4   ? UNP P62873 ?   ?   'expression tag'        -6  8  
2 8WWH HIS B 5   ? UNP P62873 ?   ?   'expression tag'        -5  9  
2 8WWH HIS B 6   ? UNP P62873 ?   ?   'expression tag'        -4  10 
2 8WWH HIS B 7   ? UNP P62873 ?   ?   'expression tag'        -3  11 
2 8WWH GLY B 8   ? UNP P62873 ?   ?   'expression tag'        -2  12 
2 8WWH SER B 9   ? UNP P62873 ?   ?   'expression tag'        -1  13 
2 8WWH SER B 10  ? UNP P62873 ?   ?   'expression tag'        0   14 
2 8WWH GLY B 11  ? UNP P62873 ?   ?   'expression tag'        1   15 
2 8WWH GLY B 351 ? UNP P62873 ?   ?   'expression tag'        341 16 
2 8WWH SER B 352 ? UNP P62873 ?   ?   'expression tag'        342 17 
2 8WWH SER B 353 ? UNP P62873 ?   ?   'expression tag'        343 18 
2 8WWH GLY B 354 ? UNP P62873 ?   ?   'expression tag'        344 19 
2 8WWH GLY B 355 ? UNP P62873 ?   ?   'expression tag'        345 20 
2 8WWH GLY B 356 ? UNP P62873 ?   ?   'expression tag'        346 21 
2 8WWH GLY B 357 ? UNP P62873 ?   ?   'expression tag'        347 22 
2 8WWH SER B 358 ? UNP P62873 ?   ?   'expression tag'        348 23 
2 8WWH GLY B 359 ? UNP P62873 ?   ?   'expression tag'        349 24 
2 8WWH GLY B 360 ? UNP P62873 ?   ?   'expression tag'        350 25 
2 8WWH GLY B 361 ? UNP P62873 ?   ?   'expression tag'        351 26 
2 8WWH GLY B 362 ? UNP P62873 ?   ?   'expression tag'        352 27 
2 8WWH SER B 363 ? UNP P62873 ?   ?   'expression tag'        353 28 
2 8WWH SER B 364 ? UNP P62873 ?   ?   'expression tag'        354 29 
2 8WWH GLY B 365 ? UNP P62873 ?   ?   'expression tag'        355 30 
2 8WWH VAL B 366 ? UNP P62873 ?   ?   'expression tag'        356 31 
2 8WWH SER B 367 ? UNP P62873 ?   ?   'expression tag'        357 32 
2 8WWH GLY B 368 ? UNP P62873 ?   ?   'expression tag'        358 33 
2 8WWH TRP B 369 ? UNP P62873 ?   ?   'expression tag'        359 34 
2 8WWH ARG B 370 ? UNP P62873 ?   ?   'expression tag'        360 35 
2 8WWH LEU B 371 ? UNP P62873 ?   ?   'expression tag'        361 36 
2 8WWH PHE B 372 ? UNP P62873 ?   ?   'expression tag'        362 37 
2 8WWH LYS B 373 ? UNP P62873 ?   ?   'expression tag'        363 38 
2 8WWH LYS B 374 ? UNP P62873 ?   ?   'expression tag'        364 39 
2 8WWH ILE B 375 ? UNP P62873 ?   ?   'expression tag'        365 40 
2 8WWH SER B 376 ? UNP P62873 ?   ?   'expression tag'        366 41 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   pentameric 
_pdbx_struct_assembly.oligomeric_count     5 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 6   ? ARG A 32  ? SER A 6   ARG A 32  1 ? 27 
HELX_P HELX_P2  AA2 GLY A 45  ? MET A 53  ? GLY A 45  MET A 53  1 ? 9  
HELX_P HELX_P3  AA3 GLU A 207 ? ILE A 212 ? GLU A 207 ILE A 212 1 ? 6  
HELX_P HELX_P4  AA4 HIS A 213 ? GLU A 216 ? HIS A 213 GLU A 216 5 ? 4  
HELX_P HELX_P5  AA5 ASN A 241 ? ASN A 255 ? ASN A 241 ASN A 255 1 ? 15 
HELX_P HELX_P6  AA6 ASN A 256 ? THR A 260 ? ASN A 256 THR A 260 5 ? 5  
HELX_P HELX_P7  AA7 LYS A 270 ? SER A 281 ? LYS A 270 SER A 281 1 ? 12 
HELX_P HELX_P8  AA8 PRO A 282 ? CYS A 286 ? PRO A 282 CYS A 286 5 ? 5  
HELX_P HELX_P9  AA9 THR A 295 ? LEU A 310 ? THR A 295 LEU A 310 1 ? 16 
HELX_P HELX_P10 AB1 LYS A 330 ? CYS A 351 ? LYS A 330 CYS A 351 1 ? 22 
HELX_P HELX_P11 AB2 GLU B 13  ? CYS B 35  ? GLU B 3   CYS B 25  1 ? 23 
HELX_P HELX_P12 AB3 THR B 39  ? THR B 44  ? THR B 29  THR B 34  1 ? 6  
HELX_P HELX_P13 AB4 ALA C 7   ? ASN C 24  ? ALA C 7   ASN C 24  1 ? 18 
HELX_P HELX_P14 AB5 LYS C 29  ? HIS C 44  ? LYS C 29  HIS C 44  1 ? 16 
HELX_P HELX_P15 AB6 PRO C 55  ? ASN C 59  ? PRO C 55  ASN C 59  5 ? 5  
HELX_P HELX_P16 AB7 ALA D 28  ? PHE D 32  ? ALA E 28  PHE E 32  5 ? 5  
HELX_P HELX_P17 AB8 ARG D 87  ? THR D 91  ? ARG E 87  THR E 91  5 ? 5  
HELX_P HELX_P18 AB9 ILE E 161 ? SER E 191 ? ILE R 108 SER R 138 1 ? 31 
HELX_P HELX_P19 AC1 ASN E 198 ? GLY E 217 ? ASN R 145 GLY R 164 1 ? 20 
HELX_P HELX_P20 AC2 MET E 218 ? HIS E 223 ? MET R 165 HIS R 170 1 ? 6  
HELX_P HELX_P21 AC3 PHE E 233 ? HIS E 269 ? PHE R 180 HIS R 216 1 ? 37 
HELX_P HELX_P22 AC4 ILE E 271 ? PHE E 276 ? ILE R 218 PHE R 223 5 ? 6  
HELX_P HELX_P23 AC5 LYS E 278 ? ILE E 297 ? LYS R 225 ILE R 244 1 ? 20 
HELX_P HELX_P24 AC6 ILE E 297 ? TYR E 303 ? ILE R 244 TYR R 250 1 ? 7  
HELX_P HELX_P25 AC7 ASN E 322 ? PHE E 339 ? ASN R 269 PHE R 286 1 ? 18 
HELX_P HELX_P26 AC8 PHE E 339 ? ARG E 356 ? PHE R 286 ARG R 303 1 ? 18 
HELX_P HELX_P27 AC9 GLN E 366 ? ILE E 404 ? GLN R 313 ILE R 351 1 ? 39 
HELX_P HELX_P28 AD1 THR E 408 ? CYS E 437 ? THR R 355 CYS R 384 1 ? 30 
HELX_P HELX_P29 AD2 CYS E 437 ? VAL E 448 ? CYS R 384 VAL R 395 1 ? 12 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? D CYS 22  SG ? ? ? 1_555 D CYS 96  SG ? ? E CYS 22  E CYS 96  1_555 ? ? ? ? ? ? ? 2.031 ? ? 
disulf2 disulf ? ? D CYS 159 SG ? ? ? 1_555 D CYS 229 SG ? ? E CYS 159 E CYS 229 1_555 ? ? ? ? ? ? ? 2.032 ? ? 
disulf3 disulf ? ? E CYS 238 SG ? ? ? 1_555 E CYS 316 SG ? ? R CYS 185 R CYS 263 1_555 ? ? ? ? ? ? ? 2.030 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS D 22  ? CYS D 96  ? CYS E 22  ? 1_555 CYS E 96  ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS D 159 ? CYS D 229 ? CYS E 159 ? 1_555 CYS E 229 ? 1_555 SG SG . . . None 'Disulfide bridge' 
3 CYS E 238 ? CYS E 316 ? CYS R 185 ? 1_555 CYS R 263 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          TYR 
_struct_mon_prot_cis.label_seq_id           235 
_struct_mon_prot_cis.label_asym_id          D 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           TYR 
_struct_mon_prot_cis.auth_seq_id            235 
_struct_mon_prot_cis.auth_asym_id           E 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    236 
_struct_mon_prot_cis.pdbx_label_asym_id_2   D 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     236 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    E 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       5.03 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 6 ? 
AA2 ? 4 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 4 ? 
AA6 ? 4 ? 
AA7 ? 4 ? 
AA8 ? 4 ? 
AA9 ? 4 ? 
AB1 ? 6 ? 
AB2 ? 4 ? 
AB3 ? 4 ? 
AB4 ? 6 ? 
AB5 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? parallel      
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB1 4 5 ? anti-parallel 
AB1 5 6 ? anti-parallel 
AB2 1 2 ? parallel      
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB4 1 2 ? parallel      
AB4 2 3 ? anti-parallel 
AB4 3 4 ? anti-parallel 
AB4 4 5 ? anti-parallel 
AB4 5 6 ? anti-parallel 
AB5 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 VAL A 185 ? THR A 190 ? VAL A 185 THR A 190 
AA1 2 HIS A 195 ? ASP A 200 ? HIS A 195 ASP A 200 
AA1 3 GLU A 33  ? GLY A 40  ? GLU A 33  GLY A 40  
AA1 4 ALA A 220 ? ALA A 226 ? ALA A 220 ALA A 226 
AA1 5 SER A 263 ? ASN A 269 ? SER A 263 ASN A 269 
AA1 6 ILE A 319 ? PHE A 323 ? ILE A 319 PHE A 323 
AA2 1 ARG B 56  ? LEU B 61  ? ARG B 46  LEU B 51  
AA2 2 LEU B 346 ? ASN B 350 ? LEU B 336 ASN B 340 
AA2 3 VAL B 337 ? SER B 341 ? VAL B 327 SER B 331 
AA2 4 VAL B 325 ? VAL B 330 ? VAL B 315 VAL B 320 
AA3 1 ILE B 68  ? TRP B 73  ? ILE B 58  TRP B 63  
AA3 2 LEU B 79  ? SER B 84  ? LEU B 69  SER B 74  
AA3 3 LYS B 88  ? ASP B 93  ? LYS B 78  ASP B 83  
AA3 4 ASN B 98  ? PRO B 104 ? ASN B 88  PRO B 94  
AA4 1 VAL B 110 ? TYR B 115 ? VAL B 100 TYR B 105 
AA4 2 TYR B 121 ? GLY B 126 ? TYR B 111 GLY B 116 
AA4 3 CYS B 131 ? ASN B 135 ? CYS B 121 ASN B 125 
AA4 4 ARG B 144 ? LEU B 149 ? ARG B 134 LEU B 139 
AA5 1 LEU B 156 ? PHE B 161 ? LEU B 146 PHE B 151 
AA5 2 GLN B 166 ? SER B 171 ? GLN B 156 SER B 161 
AA5 3 CYS B 176 ? ASP B 180 ? CYS B 166 ASP B 170 
AA5 4 GLN B 185 ? PHE B 190 ? GLN B 175 PHE B 180 
AA6 1 VAL B 197 ? LEU B 202 ? VAL B 187 LEU B 192 
AA6 2 LEU B 208 ? ALA B 213 ? LEU B 198 ALA B 203 
AA6 3 SER B 217 ? ASP B 222 ? SER B 207 ASP B 212 
AA6 4 CYS B 228 ? THR B 233 ? CYS B 218 THR B 223 
AA7 1 ILE B 239 ? PHE B 244 ? ILE B 229 PHE B 234 
AA7 2 ALA B 250 ? SER B 255 ? ALA B 240 SER B 245 
AA7 3 CYS B 260 ? ASP B 264 ? CYS B 250 ASP B 254 
AA7 4 GLN B 269 ? TYR B 274 ? GLN B 259 TYR B 264 
AA8 1 ILE B 283 ? PHE B 288 ? ILE B 273 PHE B 278 
AA8 2 LEU B 294 ? TYR B 299 ? LEU B 284 TYR B 289 
AA8 3 CYS B 304 ? ASP B 308 ? CYS B 294 ASP B 298 
AA8 4 ARG B 314 ? LEU B 318 ? ARG B 304 LEU B 308 
AA9 1 GLN D 3   ? SER D 7   ? GLN E 3   SER E 7   
AA9 2 ARG D 18  ? SER D 25  ? ARG E 18  SER E 25  
AA9 3 THR D 78  ? MET D 83  ? THR E 78  MET E 83  
AA9 4 PHE D 68  ? ASP D 73  ? PHE E 68  ASP E 73  
AB1 1 LEU D 11  ? VAL D 12  ? LEU E 11  VAL E 12  
AB1 2 THR D 115 ? VAL D 119 ? THR E 115 VAL E 119 
AB1 3 ALA D 92  ? SER D 99  ? ALA E 92  SER E 99  
AB1 4 GLY D 33  ? GLN D 39  ? GLY E 33  GLN E 39  
AB1 5 LEU D 45  ? ILE D 51  ? LEU E 45  ILE E 51  
AB1 6 ILE D 58  ? TYR D 60  ? ILE E 58  TYR E 60  
AB2 1 LEU D 11  ? VAL D 12  ? LEU E 11  VAL E 12  
AB2 2 THR D 115 ? VAL D 119 ? THR E 115 VAL E 119 
AB2 3 ALA D 92  ? SER D 99  ? ALA E 92  SER E 99  
AB2 4 PHE D 110 ? TRP D 111 ? PHE E 110 TRP E 111 
AB3 1 MET D 140 ? THR D 141 ? MET E 140 THR E 141 
AB3 2 VAL D 155 ? SER D 161 ? VAL E 155 SER E 161 
AB3 3 ALA D 211 ? ILE D 216 ? ALA E 211 ILE E 216 
AB3 4 PHE D 203 ? SER D 208 ? PHE E 203 SER E 208 
AB4 1 SER D 146 ? PRO D 148 ? SER E 146 PRO E 148 
AB4 2 THR D 243 ? GLU D 246 ? THR E 243 GLU E 246 
AB4 3 VAL D 226 ? GLN D 231 ? VAL E 226 GLN E 231 
AB4 4 LEU D 174 ? GLN D 179 ? LEU E 174 GLN E 179 
AB4 5 PRO D 185 ? TYR D 190 ? PRO E 185 TYR E 190 
AB4 6 ASN D 194 ? LEU D 195 ? ASN E 194 LEU E 195 
AB5 1 LEU E 306 ? PRO E 308 ? LEU R 253 PRO R 255 
AB5 2 VAL E 314 ? CYS E 316 ? VAL R 261 CYS R 263 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N VAL A 185 ? N VAL A 185 O ASP A 200 ? O ASP A 200 
AA1 2 3 O LYS A 197 ? O LYS A 197 N VAL A 34  ? N VAL A 34  
AA1 3 4 N LEU A 39  ? N LEU A 39  O ILE A 222 ? O ILE A 222 
AA1 4 5 N ILE A 221 ? N ILE A 221 O ILE A 265 ? O ILE A 265 
AA1 5 6 N LEU A 266 ? N LEU A 266 O TYR A 320 ? O TYR A 320 
AA2 1 2 N LEU B 61  ? N LEU B 51  O LEU B 346 ? O LEU B 336 
AA2 2 3 O TRP B 349 ? O TRP B 339 N VAL B 337 ? N VAL B 327 
AA2 3 4 O ALA B 338 ? O ALA B 328 N GLY B 329 ? N GLY B 319 
AA3 1 2 N ALA B 70  ? N ALA B 60  O ALA B 83  ? O ALA B 73  
AA3 2 3 N LEU B 80  ? N LEU B 70  O TRP B 92  ? O TRP B 82  
AA3 3 4 N LEU B 89  ? N LEU B 79  O ILE B 103 ? O ILE B 93  
AA4 1 2 N ALA B 114 ? N ALA B 104 O ALA B 123 ? O ALA B 113 
AA4 2 3 N VAL B 122 ? N VAL B 112 O TYR B 134 ? O TYR B 124 
AA4 3 4 N ILE B 133 ? N ILE B 123 O ARG B 147 ? O ARG B 137 
AA5 1 2 N ARG B 160 ? N ARG B 150 O VAL B 168 ? O VAL B 158 
AA5 2 3 N THR B 169 ? N THR B 159 O ALA B 177 ? O ALA B 167 
AA5 3 4 N CYS B 176 ? N CYS B 166 O PHE B 190 ? O PHE B 180 
AA6 1 2 N MET B 198 ? N MET B 188 O GLY B 212 ? O GLY B 202 
AA6 2 3 N PHE B 209 ? N PHE B 199 O TRP B 221 ? O TRP B 211 
AA6 3 4 N ALA B 218 ? N ALA B 208 O PHE B 232 ? O PHE B 222 
AA7 1 2 N ASN B 240 ? N ASN B 230 O GLY B 254 ? O GLY B 244 
AA7 2 3 N PHE B 251 ? N PHE B 241 O PHE B 263 ? O PHE B 253 
AA7 3 4 N CYS B 260 ? N CYS B 250 O TYR B 274 ? O TYR B 264 
AA8 1 2 N SER B 287 ? N SER B 277 O LEU B 296 ? O LEU B 286 
AA8 2 3 N LEU B 295 ? N LEU B 285 O TRP B 307 ? O TRP B 297 
AA8 3 4 N CYS B 304 ? N CYS B 294 O LEU B 318 ? O LEU B 308 
AA9 1 2 N SER D 7   ? N SER E 7   O SER D 21  ? O SER E 21  
AA9 2 3 N CYS D 22  ? N CYS E 22  O LEU D 79  ? O LEU E 79  
AA9 3 4 O GLN D 82  ? O GLN E 82  N THR D 69  ? N THR E 69  
AB1 1 2 N VAL D 12  ? N VAL E 12  O THR D 118 ? O THR E 118 
AB1 2 3 O THR D 115 ? O THR E 115 N TYR D 94  ? N TYR E 94  
AB1 3 4 O TYR D 95  ? O TYR E 95  N VAL D 37  ? N VAL E 37  
AB1 4 5 N TRP D 36  ? N TRP E 36  O VAL D 48  ? O VAL E 48  
AB1 5 6 N TYR D 50  ? N TYR E 50  O TYR D 59  ? O TYR E 59  
AB2 1 2 N VAL D 12  ? N VAL E 12  O THR D 118 ? O THR E 118 
AB2 2 3 O THR D 115 ? O THR E 115 N TYR D 94  ? N TYR E 94  
AB2 3 4 N ARG D 98  ? N ARG E 98  O PHE D 110 ? O PHE E 110 
AB3 1 2 N THR D 141 ? N THR E 141 O ARG D 160 ? O ARG E 160 
AB3 2 3 N VAL D 155 ? N VAL E 155 O ILE D 216 ? O ILE E 216 
AB3 3 4 O THR D 213 ? O THR E 213 N SER D 206 ? N SER E 206 
AB4 1 2 N VAL D 147 ? N VAL E 147 O LYS D 244 ? O LYS E 244 
AB4 2 3 O THR D 243 ? O THR E 243 N TYR D 227 ? N TYR E 227 
AB4 3 4 O MET D 230 ? O MET E 230 N TYR D 175 ? N TYR E 175 
AB4 4 5 N TRP D 176 ? N TRP E 176 O ILE D 189 ? O ILE E 189 
AB4 5 6 N TYR D 190 ? N TYR E 190 O ASN D 194 ? O ASN E 194 
AB5 1 2 N ILE E 307 ? N ILE R 254 O GLY E 315 ? O GLY R 262 
# 
_pdbx_entry_details.entry_id                   8WWH 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_close_contact.id               1 
_pdbx_validate_close_contact.PDB_model_num    1 
_pdbx_validate_close_contact.auth_atom_id_1   O 
_pdbx_validate_close_contact.auth_asym_id_1   R 
_pdbx_validate_close_contact.auth_comp_id_1   SER 
_pdbx_validate_close_contact.auth_seq_id_1    243 
_pdbx_validate_close_contact.PDB_ins_code_1   ? 
_pdbx_validate_close_contact.label_alt_id_1   ? 
_pdbx_validate_close_contact.auth_atom_id_2   OH 
_pdbx_validate_close_contact.auth_asym_id_2   R 
_pdbx_validate_close_contact.auth_comp_id_2   TYR 
_pdbx_validate_close_contact.auth_seq_id_2    280 
_pdbx_validate_close_contact.PDB_ins_code_2   ? 
_pdbx_validate_close_contact.label_alt_id_2   ? 
_pdbx_validate_close_contact.dist             2.16 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 MET E 192 ? ? 73.68   -15.60 
2 1 ARG R 224 ? ? -94.36  57.83  
3 1 PHE R 286 ? ? -121.15 -53.00 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8WWH 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8WWH 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.84 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               247274 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'MCHR1 complex S1 state' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3, 4, 5' 
# 
_em_imaging.entry_id                        8WWH 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1200 
_em_imaging.nominal_defocus_max             2200 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8WWH 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8WWH 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1   ? A MET 1   
2   1 Y 1 A GLY 2   ? A GLY 2   
3   1 Y 1 A CYS 3   ? A CYS 3   
4   1 Y 1 A ILE 55  ? A ILE 55  
5   1 Y 1 A ILE 56  ? A ILE 56  
6   1 Y 1 A HIS 57  ? A HIS 57  
7   1 Y 1 A GLU 58  ? A GLU 58  
8   1 Y 1 A ALA 59  ? A ALA 59  
9   1 Y 1 A GLY 60  ? A GLY 60  
10  1 Y 1 A TYR 61  ? A TYR 61  
11  1 Y 1 A SER 62  ? A SER 62  
12  1 Y 1 A GLU 63  ? A GLU 63  
13  1 Y 1 A GLU 64  ? A GLU 64  
14  1 Y 1 A GLU 65  ? A GLU 65  
15  1 Y 1 A CYS 66  ? A CYS 66  
16  1 Y 1 A LYS 67  ? A LYS 67  
17  1 Y 1 A GLN 68  ? A GLN 68  
18  1 Y 1 A TYR 69  ? A TYR 69  
19  1 Y 1 A LYS 70  ? A LYS 70  
20  1 Y 1 A ALA 71  ? A ALA 71  
21  1 Y 1 A VAL 72  ? A VAL 72  
22  1 Y 1 A VAL 73  ? A VAL 73  
23  1 Y 1 A TYR 74  ? A TYR 74  
24  1 Y 1 A SER 75  ? A SER 75  
25  1 Y 1 A ASN 76  ? A ASN 76  
26  1 Y 1 A THR 77  ? A THR 77  
27  1 Y 1 A ILE 78  ? A ILE 78  
28  1 Y 1 A GLN 79  ? A GLN 79  
29  1 Y 1 A SER 80  ? A SER 80  
30  1 Y 1 A ILE 81  ? A ILE 81  
31  1 Y 1 A ILE 82  ? A ILE 82  
32  1 Y 1 A ALA 83  ? A ALA 83  
33  1 Y 1 A ILE 84  ? A ILE 84  
34  1 Y 1 A ILE 85  ? A ILE 85  
35  1 Y 1 A ARG 86  ? A ARG 86  
36  1 Y 1 A ALA 87  ? A ALA 87  
37  1 Y 1 A MET 88  ? A MET 88  
38  1 Y 1 A GLY 89  ? A GLY 89  
39  1 Y 1 A ARG 90  ? A ARG 90  
40  1 Y 1 A LEU 91  ? A LEU 91  
41  1 Y 1 A LYS 92  ? A LYS 92  
42  1 Y 1 A ILE 93  ? A ILE 93  
43  1 Y 1 A ASP 94  ? A ASP 94  
44  1 Y 1 A PHE 95  ? A PHE 95  
45  1 Y 1 A GLY 96  ? A GLY 96  
46  1 Y 1 A ASP 97  ? A ASP 97  
47  1 Y 1 A SER 98  ? A SER 98  
48  1 Y 1 A ALA 99  ? A ALA 99  
49  1 Y 1 A ARG 100 ? A ARG 100 
50  1 Y 1 A ALA 101 ? A ALA 101 
51  1 Y 1 A ASP 102 ? A ASP 102 
52  1 Y 1 A ASP 103 ? A ASP 103 
53  1 Y 1 A ALA 104 ? A ALA 104 
54  1 Y 1 A ARG 105 ? A ARG 105 
55  1 Y 1 A GLN 106 ? A GLN 106 
56  1 Y 1 A LEU 107 ? A LEU 107 
57  1 Y 1 A PHE 108 ? A PHE 108 
58  1 Y 1 A VAL 109 ? A VAL 109 
59  1 Y 1 A LEU 110 ? A LEU 110 
60  1 Y 1 A ALA 111 ? A ALA 111 
61  1 Y 1 A GLY 112 ? A GLY 112 
62  1 Y 1 A ALA 113 ? A ALA 113 
63  1 Y 1 A ALA 114 ? A ALA 114 
64  1 Y 1 A GLU 115 ? A GLU 115 
65  1 Y 1 A GLU 116 ? A GLU 116 
66  1 Y 1 A GLY 117 ? A GLY 117 
67  1 Y 1 A PHE 118 ? A PHE 118 
68  1 Y 1 A MET 119 ? A MET 119 
69  1 Y 1 A THR 120 ? A THR 120 
70  1 Y 1 A ALA 121 ? A ALA 121 
71  1 Y 1 A GLU 122 ? A GLU 122 
72  1 Y 1 A LEU 123 ? A LEU 123 
73  1 Y 1 A ALA 124 ? A ALA 124 
74  1 Y 1 A GLY 125 ? A GLY 125 
75  1 Y 1 A VAL 126 ? A VAL 126 
76  1 Y 1 A ILE 127 ? A ILE 127 
77  1 Y 1 A LYS 128 ? A LYS 128 
78  1 Y 1 A ARG 129 ? A ARG 129 
79  1 Y 1 A LEU 130 ? A LEU 130 
80  1 Y 1 A TRP 131 ? A TRP 131 
81  1 Y 1 A LYS 132 ? A LYS 132 
82  1 Y 1 A ASP 133 ? A ASP 133 
83  1 Y 1 A SER 134 ? A SER 134 
84  1 Y 1 A GLY 135 ? A GLY 135 
85  1 Y 1 A VAL 136 ? A VAL 136 
86  1 Y 1 A GLN 137 ? A GLN 137 
87  1 Y 1 A ALA 138 ? A ALA 138 
88  1 Y 1 A CYS 139 ? A CYS 139 
89  1 Y 1 A PHE 140 ? A PHE 140 
90  1 Y 1 A ASN 141 ? A ASN 141 
91  1 Y 1 A ARG 142 ? A ARG 142 
92  1 Y 1 A SER 143 ? A SER 143 
93  1 Y 1 A ARG 144 ? A ARG 144 
94  1 Y 1 A GLU 145 ? A GLU 145 
95  1 Y 1 A TYR 146 ? A TYR 146 
96  1 Y 1 A GLN 147 ? A GLN 147 
97  1 Y 1 A LEU 148 ? A LEU 148 
98  1 Y 1 A ASN 149 ? A ASN 149 
99  1 Y 1 A ASP 150 ? A ASP 150 
100 1 Y 1 A SER 151 ? A SER 151 
101 1 Y 1 A ALA 152 ? A ALA 152 
102 1 Y 1 A ALA 153 ? A ALA 153 
103 1 Y 1 A TYR 154 ? A TYR 154 
104 1 Y 1 A TYR 155 ? A TYR 155 
105 1 Y 1 A LEU 156 ? A LEU 156 
106 1 Y 1 A ASN 157 ? A ASN 157 
107 1 Y 1 A ASP 158 ? A ASP 158 
108 1 Y 1 A LEU 159 ? A LEU 159 
109 1 Y 1 A ASP 160 ? A ASP 160 
110 1 Y 1 A ARG 161 ? A ARG 161 
111 1 Y 1 A ILE 162 ? A ILE 162 
112 1 Y 1 A ALA 163 ? A ALA 163 
113 1 Y 1 A GLN 164 ? A GLN 164 
114 1 Y 1 A PRO 165 ? A PRO 165 
115 1 Y 1 A ASN 166 ? A ASN 166 
116 1 Y 1 A TYR 167 ? A TYR 167 
117 1 Y 1 A ILE 168 ? A ILE 168 
118 1 Y 1 A PRO 169 ? A PRO 169 
119 1 Y 1 A THR 170 ? A THR 170 
120 1 Y 1 A GLN 171 ? A GLN 171 
121 1 Y 1 A GLN 172 ? A GLN 172 
122 1 Y 1 A ASP 173 ? A ASP 173 
123 1 Y 1 A VAL 174 ? A VAL 174 
124 1 Y 1 A LEU 175 ? A LEU 175 
125 1 Y 1 A ARG 176 ? A ARG 176 
126 1 Y 1 A THR 177 ? A THR 177 
127 1 Y 1 A ARG 178 ? A ARG 178 
128 1 Y 1 A VAL 179 ? A VAL 179 
129 1 Y 1 A LYS 180 ? A LYS 180 
130 1 Y 1 A THR 181 ? A THR 181 
131 1 Y 1 B MET -9  ? B MET 1   
132 1 Y 1 B HIS -8  ? B HIS 2   
133 1 Y 1 B HIS -7  ? B HIS 3   
134 1 Y 1 B HIS -6  ? B HIS 4   
135 1 Y 1 B HIS -5  ? B HIS 5   
136 1 Y 1 B HIS -4  ? B HIS 6   
137 1 Y 1 B HIS -3  ? B HIS 7   
138 1 Y 1 B GLY -2  ? B GLY 8   
139 1 Y 1 B SER -1  ? B SER 9   
140 1 Y 1 B SER 0   ? B SER 10  
141 1 Y 1 B GLY 1   ? B GLY 11  
142 1 Y 1 B GLY 344 ? B GLY 354 
143 1 Y 1 B GLY 345 ? B GLY 355 
144 1 Y 1 B GLY 346 ? B GLY 356 
145 1 Y 1 B GLY 347 ? B GLY 357 
146 1 Y 1 B SER 348 ? B SER 358 
147 1 Y 1 B GLY 349 ? B GLY 359 
148 1 Y 1 B GLY 350 ? B GLY 360 
149 1 Y 1 B GLY 351 ? B GLY 361 
150 1 Y 1 B GLY 352 ? B GLY 362 
151 1 Y 1 B SER 353 ? B SER 363 
152 1 Y 1 B SER 354 ? B SER 364 
153 1 Y 1 B GLY 355 ? B GLY 365 
154 1 Y 1 B VAL 356 ? B VAL 366 
155 1 Y 1 B SER 357 ? B SER 367 
156 1 Y 1 B GLY 358 ? B GLY 368 
157 1 Y 1 B TRP 359 ? B TRP 369 
158 1 Y 1 B ARG 360 ? B ARG 370 
159 1 Y 1 B LEU 361 ? B LEU 371 
160 1 Y 1 B PHE 362 ? B PHE 372 
161 1 Y 1 B LYS 363 ? B LYS 373 
162 1 Y 1 B LYS 364 ? B LYS 374 
163 1 Y 1 B ILE 365 ? B ILE 375 
164 1 Y 1 B SER 366 ? B SER 376 
165 1 Y 1 C MET 1   ? C MET 1   
166 1 Y 1 C ALA 2   ? C ALA 2   
167 1 Y 1 C SER 3   ? C SER 3   
168 1 Y 1 C ASN 4   ? C ASN 4   
169 1 Y 1 C ASN 5   ? C ASN 5   
170 1 Y 1 C GLU 63  ? C GLU 63  
171 1 Y 1 C LYS 64  ? C LYS 64  
172 1 Y 1 C LYS 65  ? C LYS 65  
173 1 Y 1 C PHE 66  ? C PHE 66  
174 1 Y 1 C PHE 67  ? C PHE 67  
175 1 Y 1 C CYS 68  ? C CYS 68  
176 1 Y 1 C ALA 69  ? C ALA 69  
177 1 Y 1 C ILE 70  ? C ILE 70  
178 1 Y 1 C LEU 71  ? C LEU 71  
179 1 Y 1 E SER 121 ? D SER 121 
180 1 Y 1 E GLY 122 ? D GLY 122 
181 1 Y 1 E GLY 123 ? D GLY 123 
182 1 Y 1 E GLY 124 ? D GLY 124 
183 1 Y 1 E GLY 125 ? D GLY 125 
184 1 Y 1 E SER 126 ? D SER 126 
185 1 Y 1 E GLY 127 ? D GLY 127 
186 1 Y 1 E GLY 128 ? D GLY 128 
187 1 Y 1 E GLY 129 ? D GLY 129 
188 1 Y 1 E GLY 130 ? D GLY 130 
189 1 Y 1 E SER 131 ? D SER 131 
190 1 Y 1 E GLY 132 ? D GLY 132 
191 1 Y 1 E GLY 133 ? D GLY 133 
192 1 Y 1 E GLY 134 ? D GLY 134 
193 1 Y 1 E GLY 135 ? D GLY 135 
194 1 Y 1 E SER 136 ? D SER 136 
195 1 Y 1 E LEU 248 ? D LEU 248 
196 1 Y 1 E GLU 249 ? D GLU 249 
197 1 Y 1 E GLU 250 ? D GLU 250 
198 1 Y 1 E ASN 251 ? D ASN 251 
199 1 Y 1 E LEU 252 ? D LEU 252 
200 1 Y 1 E TYR 253 ? D TYR 253 
201 1 Y 1 E PHE 254 ? D PHE 254 
202 1 Y 1 E GLN 255 ? D GLN 255 
203 1 Y 1 R ASP -52 ? E ASP 1   
204 1 Y 1 R TYR -51 ? E TYR 2   
205 1 Y 1 R LYS -50 ? E LYS 3   
206 1 Y 1 R ASP -49 ? E ASP 4   
207 1 Y 1 R ASP -48 ? E ASP 5   
208 1 Y 1 R ASP -47 ? E ASP 6   
209 1 Y 1 R ASP -46 ? E ASP 7   
210 1 Y 1 R HIS -45 ? E HIS 8   
211 1 Y 1 R HIS -44 ? E HIS 9   
212 1 Y 1 R HIS -43 ? E HIS 10  
213 1 Y 1 R HIS -42 ? E HIS 11  
214 1 Y 1 R HIS -41 ? E HIS 12  
215 1 Y 1 R HIS -40 ? E HIS 13  
216 1 Y 1 R HIS -39 ? E HIS 14  
217 1 Y 1 R HIS -38 ? E HIS 15  
218 1 Y 1 R GLY -37 ? E GLY 16  
219 1 Y 1 R GLN -36 ? E GLN 17  
220 1 Y 1 R PRO -35 ? E PRO 18  
221 1 Y 1 R GLY -34 ? E GLY 19  
222 1 Y 1 R ASN -33 ? E ASN 20  
223 1 Y 1 R GLY -32 ? E GLY 21  
224 1 Y 1 R SER -31 ? E SER 22  
225 1 Y 1 R ALA -30 ? E ALA 23  
226 1 Y 1 R PHE -29 ? E PHE 24  
227 1 Y 1 R LEU -28 ? E LEU 25  
228 1 Y 1 R LEU -27 ? E LEU 26  
229 1 Y 1 R ALA -26 ? E ALA 27  
230 1 Y 1 R PRO -25 ? E PRO 28  
231 1 Y 1 R ASN -24 ? E ASN 29  
232 1 Y 1 R GLY -23 ? E GLY 30  
233 1 Y 1 R SER -22 ? E SER 31  
234 1 Y 1 R HIS -21 ? E HIS 32  
235 1 Y 1 R ALA -20 ? E ALA 33  
236 1 Y 1 R PRO -19 ? E PRO 34  
237 1 Y 1 R ASP -18 ? E ASP 35  
238 1 Y 1 R HIS -17 ? E HIS 36  
239 1 Y 1 R ASN -16 ? E ASN 37  
240 1 Y 1 R VAL -15 ? E VAL 38  
241 1 Y 1 R THR -14 ? E THR 39  
242 1 Y 1 R GLN -13 ? E GLN 40  
243 1 Y 1 R GLN -12 ? E GLN 41  
244 1 Y 1 R ARG -11 ? E ARG 42  
245 1 Y 1 R ASP -10 ? E ASP 43  
246 1 Y 1 R GLU -9  ? E GLU 44  
247 1 Y 1 R GLU -8  ? E GLU 45  
248 1 Y 1 R ASN -7  ? E ASN 46  
249 1 Y 1 R LEU -6  ? E LEU 47  
250 1 Y 1 R TYR -5  ? E TYR 48  
251 1 Y 1 R PHE -4  ? E PHE 49  
252 1 Y 1 R GLN -3  ? E GLN 50  
253 1 Y 1 R GLY -2  ? E GLY 51  
254 1 Y 1 R VAL -1  ? E VAL 52  
255 1 Y 1 R ASP 0   ? E ASP 53  
256 1 Y 1 R MET 1   ? E MET 54  
257 1 Y 1 R SER 2   ? E SER 55  
258 1 Y 1 R VAL 3   ? E VAL 56  
259 1 Y 1 R GLY 4   ? E GLY 57  
260 1 Y 1 R ALA 5   ? E ALA 58  
261 1 Y 1 R MET 6   ? E MET 59  
262 1 Y 1 R LYS 7   ? E LYS 60  
263 1 Y 1 R LYS 8   ? E LYS 61  
264 1 Y 1 R GLY 9   ? E GLY 62  
265 1 Y 1 R VAL 10  ? E VAL 63  
266 1 Y 1 R GLY 11  ? E GLY 64  
267 1 Y 1 R ARG 12  ? E ARG 65  
268 1 Y 1 R ALA 13  ? E ALA 66  
269 1 Y 1 R VAL 14  ? E VAL 67  
270 1 Y 1 R GLY 15  ? E GLY 68  
271 1 Y 1 R LEU 16  ? E LEU 69  
272 1 Y 1 R GLY 17  ? E GLY 70  
273 1 Y 1 R GLY 18  ? E GLY 71  
274 1 Y 1 R GLY 19  ? E GLY 72  
275 1 Y 1 R SER 20  ? E SER 73  
276 1 Y 1 R GLY 21  ? E GLY 74  
277 1 Y 1 R CYS 22  ? E CYS 75  
278 1 Y 1 R GLN 23  ? E GLN 76  
279 1 Y 1 R ALA 24  ? E ALA 77  
280 1 Y 1 R THR 25  ? E THR 78  
281 1 Y 1 R GLU 26  ? E GLU 79  
282 1 Y 1 R GLU 27  ? E GLU 80  
283 1 Y 1 R ASP 28  ? E ASP 81  
284 1 Y 1 R PRO 29  ? E PRO 82  
285 1 Y 1 R LEU 30  ? E LEU 83  
286 1 Y 1 R PRO 31  ? E PRO 84  
287 1 Y 1 R ASN 32  ? E ASN 85  
288 1 Y 1 R CYS 33  ? E CYS 86  
289 1 Y 1 R GLY 34  ? E GLY 87  
290 1 Y 1 R ALA 35  ? E ALA 88  
291 1 Y 1 R CYS 36  ? E CYS 89  
292 1 Y 1 R ALA 37  ? E ALA 90  
293 1 Y 1 R PRO 38  ? E PRO 91  
294 1 Y 1 R GLY 39  ? E GLY 92  
295 1 Y 1 R GLN 40  ? E GLN 93  
296 1 Y 1 R GLY 41  ? E GLY 94  
297 1 Y 1 R GLY 42  ? E GLY 95  
298 1 Y 1 R ARG 43  ? E ARG 96  
299 1 Y 1 R ARG 44  ? E ARG 97  
300 1 Y 1 R TRP 45  ? E TRP 98  
301 1 Y 1 R ARG 46  ? E ARG 99  
302 1 Y 1 R LEU 47  ? E LEU 100 
303 1 Y 1 R PRO 48  ? E PRO 101 
304 1 Y 1 R GLN 49  ? E GLN 102 
305 1 Y 1 R PRO 50  ? E PRO 103 
306 1 Y 1 R ALA 51  ? E ALA 104 
307 1 Y 1 R TRP 52  ? E TRP 105 
308 1 Y 1 R VAL 53  ? E VAL 106 
309 1 Y 1 R GLU 54  ? E GLU 107 
310 1 Y 1 R GLY 55  ? E GLY 108 
311 1 Y 1 R SER 56  ? E SER 109 
312 1 Y 1 R SER 57  ? E SER 110 
313 1 Y 1 R ALA 58  ? E ALA 111 
314 1 Y 1 R ARG 59  ? E ARG 112 
315 1 Y 1 R LEU 60  ? E LEU 113 
316 1 Y 1 R TRP 61  ? E TRP 114 
317 1 Y 1 R GLU 62  ? E GLU 115 
318 1 Y 1 R GLN 63  ? E GLN 116 
319 1 Y 1 R ALA 64  ? E ALA 117 
320 1 Y 1 R THR 65  ? E THR 118 
321 1 Y 1 R GLY 66  ? E GLY 119 
322 1 Y 1 R THR 67  ? E THR 120 
323 1 Y 1 R GLY 68  ? E GLY 121 
324 1 Y 1 R TRP 69  ? E TRP 122 
325 1 Y 1 R MET 70  ? E MET 123 
326 1 Y 1 R ASP 71  ? E ASP 124 
327 1 Y 1 R LEU 72  ? E LEU 125 
328 1 Y 1 R GLU 73  ? E GLU 126 
329 1 Y 1 R ALA 74  ? E ALA 127 
330 1 Y 1 R SER 75  ? E SER 128 
331 1 Y 1 R LEU 76  ? E LEU 129 
332 1 Y 1 R LEU 77  ? E LEU 130 
333 1 Y 1 R PRO 78  ? E PRO 131 
334 1 Y 1 R THR 79  ? E THR 132 
335 1 Y 1 R GLY 80  ? E GLY 133 
336 1 Y 1 R PRO 81  ? E PRO 134 
337 1 Y 1 R ASN 82  ? E ASN 135 
338 1 Y 1 R ALA 83  ? E ALA 136 
339 1 Y 1 R SER 84  ? E SER 137 
340 1 Y 1 R ASN 85  ? E ASN 138 
341 1 Y 1 R THR 86  ? E THR 139 
342 1 Y 1 R SER 87  ? E SER 140 
343 1 Y 1 R ASP 88  ? E ASP 141 
344 1 Y 1 R GLY 89  ? E GLY 142 
345 1 Y 1 R PRO 90  ? E PRO 143 
346 1 Y 1 R ASP 91  ? E ASP 144 
347 1 Y 1 R ASN 92  ? E ASN 145 
348 1 Y 1 R LEU 93  ? E LEU 146 
349 1 Y 1 R THR 94  ? E THR 147 
350 1 Y 1 R SER 95  ? E SER 148 
351 1 Y 1 R ALA 96  ? E ALA 149 
352 1 Y 1 R GLY 97  ? E GLY 150 
353 1 Y 1 R SER 98  ? E SER 151 
354 1 Y 1 R PRO 99  ? E PRO 152 
355 1 Y 1 R PRO 100 ? E PRO 153 
356 1 Y 1 R ARG 101 ? E ARG 154 
357 1 Y 1 R THR 102 ? E THR 155 
358 1 Y 1 R GLY 103 ? E GLY 156 
359 1 Y 1 R SER 104 ? E SER 157 
360 1 Y 1 R ILE 105 ? E ILE 158 
361 1 Y 1 R SER 106 ? E SER 159 
362 1 Y 1 R LYS 396 ? E LYS 449 
363 1 Y 1 R HIS 397 ? E HIS 450 
364 1 Y 1 R MET 398 ? E MET 451 
365 1 Y 1 R GLY 399 ? E GLY 452 
366 1 Y 1 R SER 400 ? E SER 453 
367 1 Y 1 R SER 401 ? E SER 454 
368 1 Y 1 R GLY 402 ? E GLY 455 
369 1 Y 1 R GLY 403 ? E GLY 456 
370 1 Y 1 R GLY 404 ? E GLY 457 
371 1 Y 1 R GLY 405 ? E GLY 458 
372 1 Y 1 R SER 406 ? E SER 459 
373 1 Y 1 R GLY 407 ? E GLY 460 
374 1 Y 1 R GLY 408 ? E GLY 461 
375 1 Y 1 R GLY 409 ? E GLY 462 
376 1 Y 1 R GLY 410 ? E GLY 463 
377 1 Y 1 R SER 411 ? E SER 464 
378 1 Y 1 R SER 412 ? E SER 465 
379 1 Y 1 R GLY 413 ? E GLY 466 
380 1 Y 1 R VAL 414 ? E VAL 467 
381 1 Y 1 R PHE 415 ? E PHE 468 
382 1 Y 1 R THR 416 ? E THR 469 
383 1 Y 1 R LEU 417 ? E LEU 470 
384 1 Y 1 R GLU 418 ? E GLU 471 
385 1 Y 1 R ASP 419 ? E ASP 472 
386 1 Y 1 R PHE 420 ? E PHE 473 
387 1 Y 1 R VAL 421 ? E VAL 474 
388 1 Y 1 R GLY 422 ? E GLY 475 
389 1 Y 1 R ASP 423 ? E ASP 476 
390 1 Y 1 R TRP 424 ? E TRP 477 
391 1 Y 1 R GLU 425 ? E GLU 478 
392 1 Y 1 R GLN 426 ? E GLN 479 
393 1 Y 1 R THR 427 ? E THR 480 
394 1 Y 1 R ALA 428 ? E ALA 481 
395 1 Y 1 R ALA 429 ? E ALA 482 
396 1 Y 1 R TYR 430 ? E TYR 483 
397 1 Y 1 R ASN 431 ? E ASN 484 
398 1 Y 1 R LEU 432 ? E LEU 485 
399 1 Y 1 R ASP 433 ? E ASP 486 
400 1 Y 1 R GLN 434 ? E GLN 487 
401 1 Y 1 R VAL 435 ? E VAL 488 
402 1 Y 1 R LEU 436 ? E LEU 489 
403 1 Y 1 R GLU 437 ? E GLU 490 
404 1 Y 1 R GLN 438 ? E GLN 491 
405 1 Y 1 R GLY 439 ? E GLY 492 
406 1 Y 1 R GLY 440 ? E GLY 493 
407 1 Y 1 R VAL 441 ? E VAL 494 
408 1 Y 1 R SER 442 ? E SER 495 
409 1 Y 1 R SER 443 ? E SER 496 
410 1 Y 1 R LEU 444 ? E LEU 497 
411 1 Y 1 R LEU 445 ? E LEU 498 
412 1 Y 1 R GLN 446 ? E GLN 499 
413 1 Y 1 R ASN 447 ? E ASN 500 
414 1 Y 1 R LEU 448 ? E LEU 501 
415 1 Y 1 R ALA 449 ? E ALA 502 
416 1 Y 1 R VAL 450 ? E VAL 503 
417 1 Y 1 R SER 451 ? E SER 504 
418 1 Y 1 R VAL 452 ? E VAL 505 
419 1 Y 1 R THR 453 ? E THR 506 
420 1 Y 1 R PRO 454 ? E PRO 507 
421 1 Y 1 R ILE 455 ? E ILE 508 
422 1 Y 1 R GLN 456 ? E GLN 509 
423 1 Y 1 R ARG 457 ? E ARG 510 
424 1 Y 1 R ILE 458 ? E ILE 511 
425 1 Y 1 R VAL 459 ? E VAL 512 
426 1 Y 1 R ARG 460 ? E ARG 513 
427 1 Y 1 R SER 461 ? E SER 514 
428 1 Y 1 R GLY 462 ? E GLY 515 
429 1 Y 1 R GLU 463 ? E GLU 516 
430 1 Y 1 R ASN 464 ? E ASN 517 
431 1 Y 1 R ALA 465 ? E ALA 518 
432 1 Y 1 R LEU 466 ? E LEU 519 
433 1 Y 1 R LYS 467 ? E LYS 520 
434 1 Y 1 R ILE 468 ? E ILE 521 
435 1 Y 1 R ASP 469 ? E ASP 522 
436 1 Y 1 R ILE 470 ? E ILE 523 
437 1 Y 1 R HIS 471 ? E HIS 524 
438 1 Y 1 R VAL 472 ? E VAL 525 
439 1 Y 1 R ILE 473 ? E ILE 526 
440 1 Y 1 R ILE 474 ? E ILE 527 
441 1 Y 1 R PRO 475 ? E PRO 528 
442 1 Y 1 R TYR 476 ? E TYR 529 
443 1 Y 1 R GLU 477 ? E GLU 530 
444 1 Y 1 R GLY 478 ? E GLY 531 
445 1 Y 1 R LEU 479 ? E LEU 532 
446 1 Y 1 R SER 480 ? E SER 533 
447 1 Y 1 R ALA 481 ? E ALA 534 
448 1 Y 1 R ASP 482 ? E ASP 535 
449 1 Y 1 R GLN 483 ? E GLN 536 
450 1 Y 1 R MET 484 ? E MET 537 
451 1 Y 1 R ALA 485 ? E ALA 538 
452 1 Y 1 R GLN 486 ? E GLN 539 
453 1 Y 1 R ILE 487 ? E ILE 540 
454 1 Y 1 R GLU 488 ? E GLU 541 
455 1 Y 1 R GLU 489 ? E GLU 542 
456 1 Y 1 R VAL 490 ? E VAL 543 
457 1 Y 1 R PHE 491 ? E PHE 544 
458 1 Y 1 R LYS 492 ? E LYS 545 
459 1 Y 1 R VAL 493 ? E VAL 546 
460 1 Y 1 R VAL 494 ? E VAL 547 
461 1 Y 1 R TYR 495 ? E TYR 548 
462 1 Y 1 R PRO 496 ? E PRO 549 
463 1 Y 1 R VAL 497 ? E VAL 550 
464 1 Y 1 R ASP 498 ? E ASP 551 
465 1 Y 1 R ASP 499 ? E ASP 552 
466 1 Y 1 R HIS 500 ? E HIS 553 
467 1 Y 1 R HIS 501 ? E HIS 554 
468 1 Y 1 R PHE 502 ? E PHE 555 
469 1 Y 1 R LYS 503 ? E LYS 556 
470 1 Y 1 R VAL 504 ? E VAL 557 
471 1 Y 1 R ILE 505 ? E ILE 558 
472 1 Y 1 R LEU 506 ? E LEU 559 
473 1 Y 1 R PRO 507 ? E PRO 560 
474 1 Y 1 R TYR 508 ? E TYR 561 
475 1 Y 1 R GLY 509 ? E GLY 562 
476 1 Y 1 R THR 510 ? E THR 563 
477 1 Y 1 R LEU 511 ? E LEU 564 
478 1 Y 1 R VAL 512 ? E VAL 565 
479 1 Y 1 R ILE 513 ? E ILE 566 
480 1 Y 1 R ASP 514 ? E ASP 567 
481 1 Y 1 R GLY 515 ? E GLY 568 
482 1 Y 1 R VAL 516 ? E VAL 569 
483 1 Y 1 R THR 517 ? E THR 570 
484 1 Y 1 R PRO 518 ? E PRO 571 
485 1 Y 1 R ASN 519 ? E ASN 572 
486 1 Y 1 R MET 520 ? E MET 573 
487 1 Y 1 R LEU 521 ? E LEU 574 
488 1 Y 1 R ASN 522 ? E ASN 575 
489 1 Y 1 R TYR 523 ? E TYR 576 
490 1 Y 1 R PHE 524 ? E PHE 577 
491 1 Y 1 R GLY 525 ? E GLY 578 
492 1 Y 1 R ARG 526 ? E ARG 579 
493 1 Y 1 R PRO 527 ? E PRO 580 
494 1 Y 1 R TYR 528 ? E TYR 581 
495 1 Y 1 R GLU 529 ? E GLU 582 
496 1 Y 1 R GLY 530 ? E GLY 583 
497 1 Y 1 R ILE 531 ? E ILE 584 
498 1 Y 1 R ALA 532 ? E ALA 585 
499 1 Y 1 R VAL 533 ? E VAL 586 
500 1 Y 1 R PHE 534 ? E PHE 587 
501 1 Y 1 R ASP 535 ? E ASP 588 
502 1 Y 1 R GLY 536 ? E GLY 589 
503 1 Y 1 R LYS 537 ? E LYS 590 
504 1 Y 1 R LYS 538 ? E LYS 591 
505 1 Y 1 R ILE 539 ? E ILE 592 
506 1 Y 1 R THR 540 ? E THR 593 
507 1 Y 1 R VAL 541 ? E VAL 594 
508 1 Y 1 R THR 542 ? E THR 595 
509 1 Y 1 R GLY 543 ? E GLY 596 
510 1 Y 1 R THR 544 ? E THR 597 
511 1 Y 1 R LEU 545 ? E LEU 598 
512 1 Y 1 R TRP 546 ? E TRP 599 
513 1 Y 1 R ASN 547 ? E ASN 600 
514 1 Y 1 R GLY 548 ? E GLY 601 
515 1 Y 1 R ASN 549 ? E ASN 602 
516 1 Y 1 R LYS 550 ? E LYS 603 
517 1 Y 1 R ILE 551 ? E ILE 604 
518 1 Y 1 R ILE 552 ? E ILE 605 
519 1 Y 1 R ASP 553 ? E ASP 606 
520 1 Y 1 R GLU 554 ? E GLU 607 
521 1 Y 1 R ARG 555 ? E ARG 608 
522 1 Y 1 R LEU 556 ? E LEU 609 
523 1 Y 1 R ILE 557 ? E ILE 610 
524 1 Y 1 R THR 558 ? E THR 611 
525 1 Y 1 R PRO 559 ? E PRO 612 
526 1 Y 1 R ASP 560 ? E ASP 613 
527 1 Y 1 R GLY 561 ? E GLY 614 
528 1 Y 1 R SER 562 ? E SER 615 
529 1 Y 1 R MET 563 ? E MET 616 
530 1 Y 1 R LEU 564 ? E LEU 617 
531 1 Y 1 R PHE 565 ? E PHE 618 
532 1 Y 1 R ARG 566 ? E ARG 619 
533 1 Y 1 R VAL 567 ? E VAL 620 
534 1 Y 1 R THR 568 ? E THR 621 
535 1 Y 1 R ILE 569 ? E ILE 622 
536 1 Y 1 R ASN 570 ? E ASN 623 
537 1 Y 1 R SER 571 ? E SER 624 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-10-25 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8WWH 
_em_admin.last_update        2024-11-27 
_em_admin.map_release_date   2024-11-13 
_em_admin.title              'MCHR1-Gi complex,S1 state' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          274590 
_em_entity_assembly_recombinant.organism             'Baculovirus expression vector pFastBac1-HM' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         55 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ?      ?            
'MODEL REFINEMENT'         ? 2  ? ? ? PHENIX 1.20.1_4487: 
'IMAGE ACQUISITION'        ? 3  ? ? 1 ?      ?            
MASKING                    ? 4  ? ? ? ?      ?            
'CTF CORRECTION'           ? 5  1 ? ? ?      ?            
'LAYERLINE INDEXING'       ? 6  ? ? ? ?      ?            
'DIFFRACTION INDEXING'     ? 7  ? ? ? ?      ?            
'MODEL FITTING'            ? 8  ? ? ? ?      ?            
OTHER                      ? 9  ? ? ? ?      ?            
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ?      ?            
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ?      ?            
CLASSIFICATION             ? 12 1 ? ? ?      ?            
RECONSTRUCTION             ? 13 1 ? ? ?      ?            
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           T2221005 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    8WWH 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . THR A 1 4   ? 113.510 125.686 91.793  1.00 48.13  ? 4   THR A N   1 
ATOM 2    C CA  . THR A 1 4   ? 114.106 125.824 90.470  1.00 54.24  ? 4   THR A CA  1 
ATOM 3    C C   . THR A 1 4   ? 113.224 125.192 89.402  1.00 52.16  ? 4   THR A C   1 
ATOM 4    O O   . THR A 1 4   ? 113.716 124.718 88.379  1.00 51.74  ? 4   THR A O   1 
ATOM 5    C CB  . THR A 1 4   ? 115.502 125.182 90.409  1.00 53.74  ? 4   THR A CB  1 
ATOM 6    O OG1 . THR A 1 4   ? 115.399 123.780 90.685  1.00 54.52  ? 4   THR A OG1 1 
ATOM 7    C CG2 . THR A 1 4   ? 116.427 125.827 91.426  1.00 50.41  ? 4   THR A CG2 1 
ATOM 8    N N   . LEU A 1 5   ? 111.918 125.182 89.649  1.00 47.85  ? 5   LEU A N   1 
ATOM 9    C CA  . LEU A 1 5   ? 110.945 124.633 88.718  1.00 49.16  ? 5   LEU A CA  1 
ATOM 10   C C   . LEU A 1 5   ? 110.291 125.763 87.939  1.00 52.10  ? 5   LEU A C   1 
ATOM 11   O O   . LEU A 1 5   ? 110.016 126.831 88.490  1.00 53.57  ? 5   LEU A O   1 
ATOM 12   C CB  . LEU A 1 5   ? 109.871 123.828 89.451  1.00 44.36  ? 5   LEU A CB  1 
ATOM 13   C CG  . LEU A 1 5   ? 110.281 122.570 90.212  1.00 46.67  ? 5   LEU A CG  1 
ATOM 14   C CD1 . LEU A 1 5   ? 109.072 121.980 90.912  1.00 42.18  ? 5   LEU A CD1 1 
ATOM 15   C CD2 . LEU A 1 5   ? 110.905 121.556 89.274  1.00 47.37  ? 5   LEU A CD2 1 
ATOM 16   N N   . SER A 1 6   ? 110.045 125.524 86.656  1.00 44.18  ? 6   SER A N   1 
ATOM 17   C CA  . SER A 1 6   ? 109.364 126.517 85.847  1.00 36.44  ? 6   SER A CA  1 
ATOM 18   C C   . SER A 1 6   ? 107.877 126.542 86.184  1.00 43.35  ? 6   SER A C   1 
ATOM 19   O O   . SER A 1 6   ? 107.372 125.733 86.963  1.00 47.38  ? 6   SER A O   1 
ATOM 20   C CB  . SER A 1 6   ? 109.575 126.240 84.362  1.00 34.82  ? 6   SER A CB  1 
ATOM 21   O OG  . SER A 1 6   ? 109.138 124.942 84.016  1.00 43.26  ? 6   SER A OG  1 
ATOM 22   N N   . ALA A 1 7   ? 107.171 127.501 85.586  1.00 47.84  ? 7   ALA A N   1 
ATOM 23   C CA  . ALA A 1 7   ? 105.743 127.629 85.846  1.00 41.16  ? 7   ALA A CA  1 
ATOM 24   C C   . ALA A 1 7   ? 104.982 126.393 85.395  1.00 47.96  ? 7   ALA A C   1 
ATOM 25   O O   . ALA A 1 7   ? 103.980 126.021 86.016  1.00 48.62  ? 7   ALA A O   1 
ATOM 26   C CB  . ALA A 1 7   ? 105.193 128.875 85.157  1.00 41.73  ? 7   ALA A CB  1 
ATOM 27   N N   . GLU A 1 8   ? 105.436 125.746 84.320  1.00 48.77  ? 8   GLU A N   1 
ATOM 28   C CA  . GLU A 1 8   ? 104.779 124.534 83.851  1.00 41.88  ? 8   GLU A CA  1 
ATOM 29   C C   . GLU A 1 8   ? 105.270 123.294 84.582  1.00 41.89  ? 8   GLU A C   1 
ATOM 30   O O   . GLU A 1 8   ? 104.520 122.321 84.705  1.00 54.44  ? 8   GLU A O   1 
ATOM 31   C CB  . GLU A 1 8   ? 104.985 124.370 82.348  1.00 45.80  ? 8   GLU A CB  1 
ATOM 32   C CG  . GLU A 1 8   ? 104.419 125.507 81.526  1.00 42.31  ? 8   GLU A CG  1 
ATOM 33   C CD  . GLU A 1 8   ? 104.446 125.221 80.042  1.00 52.41  ? 8   GLU A CD  1 
ATOM 34   O OE1 . GLU A 1 8   ? 104.683 124.058 79.663  1.00 59.60  ? 8   GLU A OE1 1 
ATOM 35   O OE2 . GLU A 1 8   ? 104.229 126.160 79.253  1.00 60.57  ? 8   GLU A OE2 1 
ATOM 36   N N   . ASP A 1 9   ? 106.518 123.297 85.055  1.00 40.09  ? 9   ASP A N   1 
ATOM 37   C CA  . ASP A 1 9   ? 107.000 122.183 85.863  1.00 35.57  ? 9   ASP A CA  1 
ATOM 38   C C   . ASP A 1 9   ? 106.272 122.109 87.198  1.00 36.52  ? 9   ASP A C   1 
ATOM 39   O O   . ASP A 1 9   ? 105.973 121.015 87.685  1.00 48.36  ? 9   ASP A O   1 
ATOM 40   C CB  . ASP A 1 9   ? 108.504 122.303 86.090  1.00 47.39  ? 9   ASP A CB  1 
ATOM 41   C CG  . ASP A 1 9   ? 109.308 121.975 84.855  1.00 55.27  ? 9   ASP A CG  1 
ATOM 42   O OD1 . ASP A 1 9   ? 108.697 121.714 83.798  1.00 55.19  ? 9   ASP A OD1 1 
ATOM 43   O OD2 . ASP A 1 9   ? 110.553 121.970 84.944  1.00 54.04  ? 9   ASP A OD2 1 
ATOM 44   N N   . LYS A 1 10  ? 105.989 123.261 87.811  1.00 47.47  ? 10  LYS A N   1 
ATOM 45   C CA  . LYS A 1 10  ? 105.243 123.260 89.066  1.00 42.63  ? 10  LYS A CA  1 
ATOM 46   C C   . LYS A 1 10  ? 103.832 122.734 88.869  1.00 39.62  ? 10  LYS A C   1 
ATOM 47   O O   . LYS A 1 10  ? 103.294 122.036 89.735  1.00 52.06  ? 10  LYS A O   1 
ATOM 48   C CB  . LYS A 1 10  ? 105.201 124.667 89.659  1.00 44.63  ? 10  LYS A CB  1 
ATOM 49   C CG  . LYS A 1 10  ? 106.548 125.218 90.075  1.00 47.73  ? 10  LYS A CG  1 
ATOM 50   C CD  . LYS A 1 10  ? 106.407 126.626 90.622  1.00 49.47  ? 10  LYS A CD  1 
ATOM 51   C CE  . LYS A 1 10  ? 107.755 127.208 91.005  1.00 54.70  ? 10  LYS A CE  1 
ATOM 52   N NZ  . LYS A 1 10  ? 107.630 128.599 91.521  1.00 53.23  ? 10  LYS A NZ  1 
ATOM 53   N N   . ALA A 1 11  ? 103.210 123.071 87.740  1.00 40.17  ? 11  ALA A N   1 
ATOM 54   C CA  . ALA A 1 11  ? 101.880 122.559 87.440  1.00 34.78  ? 11  ALA A CA  1 
ATOM 55   C C   . ALA A 1 11  ? 101.898 121.058 87.180  1.00 43.63  ? 11  ALA A C   1 
ATOM 56   O O   . ALA A 1 11  ? 100.935 120.361 87.516  1.00 52.08  ? 11  ALA A O   1 
ATOM 57   C CB  . ALA A 1 11  ? 101.289 123.314 86.256  1.00 30.28  ? 11  ALA A CB  1 
ATOM 58   N N   . ALA A 1 12  ? 102.972 120.549 86.574  1.00 34.22  ? 12  ALA A N   1 
ATOM 59   C CA  . ALA A 1 12  ? 103.083 119.113 86.339  1.00 26.57  ? 12  ALA A CA  1 
ATOM 60   C C   . ALA A 1 12  ? 103.286 118.359 87.645  1.00 39.56  ? 12  ALA A C   1 
ATOM 61   O O   . ALA A 1 12  ? 102.800 117.234 87.800  1.00 55.14  ? 12  ALA A O   1 
ATOM 62   C CB  . ALA A 1 12  ? 104.222 118.823 85.366  1.00 30.37  ? 12  ALA A CB  1 
ATOM 63   N N   . VAL A 1 13  ? 104.018 118.954 88.589  1.00 39.07  ? 13  VAL A N   1 
ATOM 64   C CA  . VAL A 1 13  ? 104.179 118.343 89.904  1.00 33.94  ? 13  VAL A CA  1 
ATOM 65   C C   . VAL A 1 13  ? 102.862 118.381 90.664  1.00 31.50  ? 13  VAL A C   1 
ATOM 66   O O   . VAL A 1 13  ? 102.511 117.433 91.375  1.00 40.13  ? 13  VAL A O   1 
ATOM 67   C CB  . VAL A 1 13  ? 105.307 119.038 90.687  1.00 33.71  ? 13  VAL A CB  1 
ATOM 68   C CG1 . VAL A 1 13  ? 105.415 118.463 92.083  1.00 37.67  ? 13  VAL A CG1 1 
ATOM 69   C CG2 . VAL A 1 13  ? 106.627 118.891 89.957  1.00 35.96  ? 13  VAL A CG2 1 
ATOM 70   N N   . GLU A 1 14  ? 102.115 119.477 90.533  1.00 36.85  ? 14  GLU A N   1 
ATOM 71   C CA  . GLU A 1 14  ? 100.800 119.556 91.156  1.00 32.82  ? 14  GLU A CA  1 
ATOM 72   C C   . GLU A 1 14  ? 99.850  118.527 90.560  1.00 43.65  ? 14  GLU A C   1 
ATOM 73   O O   . GLU A 1 14  ? 99.022  117.950 91.273  1.00 56.75  ? 14  GLU A O   1 
ATOM 74   C CB  . GLU A 1 14  ? 100.226 120.963 91.008  1.00 30.60  ? 14  GLU A CB  1 
ATOM 75   C CG  . GLU A 1 14  ? 98.868  121.129 91.658  1.00 44.21  ? 14  GLU A CG  1 
ATOM 76   C CD  . GLU A 1 14  ? 98.293  122.515 91.476  1.00 56.00  ? 14  GLU A CD  1 
ATOM 77   O OE1 . GLU A 1 14  ? 99.044  123.425 91.072  1.00 61.25  ? 14  GLU A OE1 1 
ATOM 78   O OE2 . GLU A 1 14  ? 97.087  122.695 91.739  1.00 56.70  ? 14  GLU A OE2 1 
ATOM 79   N N   . ARG A 1 15  ? 99.944  118.293 89.249  1.00 39.08  ? 15  ARG A N   1 
ATOM 80   C CA  . ARG A 1 15  ? 99.126  117.259 88.625  1.00 31.88  ? 15  ARG A CA  1 
ATOM 81   C C   . ARG A 1 15  ? 99.494  115.877 89.146  1.00 32.09  ? 15  ARG A C   1 
ATOM 82   O O   . ARG A 1 15  ? 98.616  115.033 89.355  1.00 37.70  ? 15  ARG A O   1 
ATOM 83   C CB  . ARG A 1 15  ? 99.283  117.311 87.107  1.00 32.39  ? 15  ARG A CB  1 
ATOM 84   C CG  . ARG A 1 15  ? 98.625  116.151 86.380  1.00 29.99  ? 15  ARG A CG  1 
ATOM 85   C CD  . ARG A 1 15  ? 98.880  116.216 84.893  1.00 30.89  ? 15  ARG A CD  1 
ATOM 86   N NE  . ARG A 1 15  ? 98.513  114.975 84.223  1.00 29.73  ? 15  ARG A NE  1 
ATOM 87   C CZ  . ARG A 1 15  ? 97.308  114.705 83.742  1.00 32.11  ? 15  ARG A CZ  1 
ATOM 88   N NH1 . ARG A 1 15  ? 96.312  115.566 83.848  1.00 34.19  ? 15  ARG A NH1 1 
ATOM 89   N NH2 . ARG A 1 15  ? 97.099  113.539 83.141  1.00 42.90  ? 15  ARG A NH2 1 
ATOM 90   N N   . SER A 1 16  ? 100.786 115.627 89.354  1.00 31.64  ? 16  SER A N   1 
ATOM 91   C CA  . SER A 1 16  ? 101.216 114.338 89.880  1.00 20.90  ? 16  SER A CA  1 
ATOM 92   C C   . SER A 1 16  ? 100.660 114.098 91.279  1.00 39.53  ? 16  SER A C   1 
ATOM 93   O O   . SER A 1 16  ? 100.247 112.981 91.609  1.00 49.05  ? 16  SER A O   1 
ATOM 94   C CB  . SER A 1 16  ? 102.738 114.260 89.883  1.00 26.84  ? 16  SER A CB  1 
ATOM 95   O OG  . SER A 1 16  ? 103.176 113.020 90.397  1.00 47.81  ? 16  SER A OG  1 
ATOM 96   N N   . LYS A 1 17  ? 100.649 115.137 92.119  1.00 48.13  ? 17  LYS A N   1 
ATOM 97   C CA  . LYS A 1 17  ? 100.074 115.018 93.455  1.00 41.15  ? 17  LYS A CA  1 
ATOM 98   C C   . LYS A 1 17  ? 98.575  114.758 93.407  1.00 41.87  ? 17  LYS A C   1 
ATOM 99   O O   . LYS A 1 17  ? 98.026  114.133 94.318  1.00 55.99  ? 17  LYS A O   1 
ATOM 100  C CB  . LYS A 1 17  ? 100.362 116.278 94.268  1.00 44.69  ? 17  LYS A CB  1 
ATOM 101  C CG  . LYS A 1 17  ? 101.833 116.529 94.521  1.00 44.74  ? 17  LYS A CG  1 
ATOM 102  C CD  . LYS A 1 17  ? 102.038 117.779 95.353  1.00 48.22  ? 17  LYS A CD  1 
ATOM 103  C CE  . LYS A 1 17  ? 103.513 118.016 95.627  1.00 54.92  ? 17  LYS A CE  1 
ATOM 104  N NZ  . LYS A 1 17  ? 103.739 119.243 96.438  1.00 57.19  ? 17  LYS A NZ  1 
ATOM 105  N N   . MET A 1 18  ? 97.896  115.241 92.368  1.00 33.20  ? 18  MET A N   1 
ATOM 106  C CA  . MET A 1 18  ? 96.485  114.916 92.196  1.00 41.78  ? 18  MET A CA  1 
ATOM 107  C C   . MET A 1 18  ? 96.306  113.446 91.845  1.00 53.18  ? 18  MET A C   1 
ATOM 108  O O   . MET A 1 18  ? 95.320  112.819 92.248  1.00 54.69  ? 18  MET A O   1 
ATOM 109  C CB  . MET A 1 18  ? 95.871  115.809 91.121  1.00 51.73  ? 18  MET A CB  1 
ATOM 110  C CG  . MET A 1 18  ? 95.713  117.256 91.537  1.00 54.60  ? 18  MET A CG  1 
ATOM 111  S SD  . MET A 1 18  ? 94.310  117.487 92.636  1.00 79.01  ? 18  MET A SD  1 
ATOM 112  C CE  . MET A 1 18  ? 92.983  116.912 91.583  1.00 50.46  ? 18  MET A CE  1 
ATOM 113  N N   . ILE A 1 19  ? 97.243  112.885 91.084  1.00 52.28  ? 19  ILE A N   1 
ATOM 114  C CA  . ILE A 1 19  ? 97.190  111.467 90.749  1.00 33.06  ? 19  ILE A CA  1 
ATOM 115  C C   . ILE A 1 19  ? 97.436  110.614 91.987  1.00 43.07  ? 19  ILE A C   1 
ATOM 116  O O   . ILE A 1 19  ? 96.720  109.638 92.234  1.00 59.97  ? 19  ILE A O   1 
ATOM 117  C CB  . ILE A 1 19  ? 98.185  111.145 89.622  1.00 32.36  ? 19  ILE A CB  1 
ATOM 118  C CG1 . ILE A 1 19  ? 97.817  111.926 88.362  1.00 35.13  ? 19  ILE A CG1 1 
ATOM 119  C CG2 . ILE A 1 19  ? 98.217  109.666 89.353  1.00 42.69  ? 19  ILE A CG2 1 
ATOM 120  C CD1 . ILE A 1 19  ? 98.765  111.724 87.227  1.00 33.05  ? 19  ILE A CD1 1 
ATOM 121  N N   . ASP A 1 20  ? 98.443  110.970 92.790  1.00 40.34  ? 20  ASP A N   1 
ATOM 122  C CA  . ASP A 1 20  ? 98.709  110.210 94.009  1.00 36.87  ? 20  ASP A CA  1 
ATOM 123  C C   . ASP A 1 20  ? 97.567  110.315 95.005  1.00 38.67  ? 20  ASP A C   1 
ATOM 124  O O   . ASP A 1 20  ? 97.335  109.381 95.778  1.00 49.40  ? 20  ASP A O   1 
ATOM 125  C CB  . ASP A 1 20  ? 99.993  110.700 94.673  1.00 43.64  ? 20  ASP A CB  1 
ATOM 126  C CG  . ASP A 1 20  ? 101.218 110.361 93.882  1.00 52.68  ? 20  ASP A CG  1 
ATOM 127  O OD1 . ASP A 1 20  ? 101.217 109.294 93.249  1.00 52.25  ? 20  ASP A OD1 1 
ATOM 128  O OD2 . ASP A 1 20  ? 102.182 111.154 93.893  1.00 56.13  ? 20  ASP A OD2 1 
ATOM 129  N N   . ARG A 1 21  ? 96.852  111.437 95.013  1.00 46.54  ? 21  ARG A N   1 
ATOM 130  C CA  . ARG A 1 21  ? 95.714  111.569 95.911  1.00 46.55  ? 21  ARG A CA  1 
ATOM 131  C C   . ARG A 1 21  ? 94.584  110.628 95.518  1.00 47.71  ? 21  ARG A C   1 
ATOM 132  O O   . ARG A 1 21  ? 93.793  110.222 96.375  1.00 57.79  ? 21  ARG A O   1 
ATOM 133  C CB  . ARG A 1 21  ? 95.238  113.018 95.917  1.00 51.17  ? 21  ARG A CB  1 
ATOM 134  C CG  . ARG A 1 21  ? 94.303  113.388 97.042  1.00 52.92  ? 21  ARG A CG  1 
ATOM 135  C CD  . ARG A 1 21  ? 94.110  114.887 97.040  1.00 54.62  ? 21  ARG A CD  1 
ATOM 136  N NE  . ARG A 1 21  ? 95.400  115.567 97.032  1.00 59.55  ? 21  ARG A NE  1 
ATOM 137  C CZ  . ARG A 1 21  ? 95.560  116.878 96.928  1.00 61.82  ? 21  ARG A CZ  1 
ATOM 138  N NH1 . ARG A 1 21  ? 94.525  117.695 96.823  1.00 60.85  ? 21  ARG A NH1 1 
ATOM 139  N NH2 . ARG A 1 21  ? 96.790  117.383 96.924  1.00 57.00  ? 21  ARG A NH2 1 
ATOM 140  N N   . ASN A 1 22  ? 94.488  110.276 94.236  1.00 43.34  ? 22  ASN A N   1 
ATOM 141  C CA  . ASN A 1 22  ? 93.503  109.301 93.788  1.00 43.78  ? 22  ASN A CA  1 
ATOM 142  C C   . ASN A 1 22  ? 94.003  107.869 93.882  1.00 53.34  ? 22  ASN A C   1 
ATOM 143  O O   . ASN A 1 22  ? 93.209  106.965 94.160  1.00 61.11  ? 22  ASN A O   1 
ATOM 144  C CB  . ASN A 1 22  ? 93.086  109.596 92.347  1.00 48.35  ? 22  ASN A CB  1 
ATOM 145  C CG  . ASN A 1 22  ? 92.418  110.943 92.201  1.00 60.91  ? 22  ASN A CG  1 
ATOM 146  O OD1 . ASN A 1 22  ? 91.803  111.448 93.139  1.00 58.69  ? 22  ASN A OD1 1 
ATOM 147  N ND2 . ASN A 1 22  ? 92.530  111.534 91.019  1.00 57.12  ? 22  ASN A ND2 1 
ATOM 148  N N   . LEU A 1 23  ? 95.298  107.637 93.646  1.00 45.85  ? 23  LEU A N   1 
ATOM 149  C CA  . LEU A 1 23  ? 95.851  106.301 93.834  1.00 43.34  ? 23  LEU A CA  1 
ATOM 150  C C   . LEU A 1 23  ? 95.756  105.872 95.289  1.00 48.07  ? 23  LEU A C   1 
ATOM 151  O O   . LEU A 1 23  ? 95.442  104.714 95.586  1.00 49.04  ? 23  LEU A O   1 
ATOM 152  C CB  . LEU A 1 23  ? 97.302  106.260 93.361  1.00 34.86  ? 23  LEU A CB  1 
ATOM 153  C CG  . LEU A 1 23  ? 97.572  106.521 91.881  1.00 38.22  ? 23  LEU A CG  1 
ATOM 154  C CD1 . LEU A 1 23  ? 99.059  106.539 91.632  1.00 39.08  ? 23  LEU A CD1 1 
ATOM 155  C CD2 . LEU A 1 23  ? 96.901  105.477 91.012  1.00 36.62  ? 23  LEU A CD2 1 
ATOM 156  N N   . ARG A 1 24  ? 96.035  106.794 96.211  1.00 50.61  ? 24  ARG A N   1 
ATOM 157  C CA  . ARG A 1 24  ? 95.857  106.510 97.629  1.00 43.25  ? 24  ARG A CA  1 
ATOM 158  C C   . ARG A 1 24  ? 94.393  106.256 97.958  1.00 41.75  ? 24  ARG A C   1 
ATOM 159  O O   . ARG A 1 24  ? 94.070  105.358 98.742  1.00 55.83  ? 24  ARG A O   1 
ATOM 160  C CB  . ARG A 1 24  ? 96.402  107.671 98.459  1.00 49.97  ? 24  ARG A CB  1 
ATOM 161  C CG  . ARG A 1 24  ? 96.333  107.464 99.957  1.00 53.23  ? 24  ARG A CG  1 
ATOM 162  C CD  . ARG A 1 24  ? 96.760  108.713 100.716 1.00 56.17  ? 24  ARG A CD  1 
ATOM 163  N NE  . ARG A 1 24  ? 98.078  109.183 100.304 1.00 64.41  ? 24  ARG A NE  1 
ATOM 164  C CZ  . ARG A 1 24  ? 98.295  110.271 99.577  1.00 58.45  ? 24  ARG A CZ  1 
ATOM 165  N NH1 . ARG A 1 24  ? 97.299  111.044 99.177  1.00 55.26  ? 24  ARG A NH1 1 
ATOM 166  N NH2 . ARG A 1 24  ? 99.542  110.590 99.242  1.00 47.24  ? 24  ARG A NH2 1 
ATOM 167  N N   . GLU A 1 25  ? 93.494  107.047 97.373  1.00 43.10  ? 25  GLU A N   1 
ATOM 168  C CA  . GLU A 1 25  ? 92.068  106.858 97.609  1.00 46.35  ? 25  GLU A CA  1 
ATOM 169  C C   . GLU A 1 25  ? 91.589  105.516 97.072  1.00 54.78  ? 25  GLU A C   1 
ATOM 170  O O   . GLU A 1 25  ? 90.783  104.834 97.714  1.00 59.68  ? 25  GLU A O   1 
ATOM 171  C CB  . GLU A 1 25  ? 91.288  108.006 96.972  1.00 48.77  ? 25  GLU A CB  1 
ATOM 172  C CG  . GLU A 1 25  ? 89.792  107.944 97.173  1.00 55.45  ? 25  GLU A CG  1 
ATOM 173  C CD  . GLU A 1 25  ? 89.076  109.083 96.478  1.00 64.79  ? 25  GLU A CD  1 
ATOM 174  O OE1 . GLU A 1 25  ? 89.732  109.809 95.701  1.00 63.85  ? 25  GLU A OE1 1 
ATOM 175  O OE2 . GLU A 1 25  ? 87.861  109.255 96.708  1.00 66.59  ? 25  GLU A OE2 1 
ATOM 176  N N   . ASP A 1 26  ? 92.067  105.122 95.890  1.00 53.56  ? 26  ASP A N   1 
ATOM 177  C CA  . ASP A 1 26  ? 91.685  103.831 95.330  1.00 48.33  ? 26  ASP A CA  1 
ATOM 178  C C   . ASP A 1 26  ? 92.320  102.675 96.089  1.00 49.40  ? 26  ASP A C   1 
ATOM 179  O O   . ASP A 1 26  ? 91.714  101.604 96.201  1.00 56.57  ? 26  ASP A O   1 
ATOM 180  C CB  . ASP A 1 26  ? 92.066  103.762 93.854  1.00 46.38  ? 26  ASP A CB  1 
ATOM 181  C CG  . ASP A 1 26  ? 91.319  104.773 93.015  1.00 55.50  ? 26  ASP A CG  1 
ATOM 182  O OD1 . ASP A 1 26  ? 90.198  105.159 93.405  1.00 59.04  ? 26  ASP A OD1 1 
ATOM 183  O OD2 . ASP A 1 26  ? 91.851  105.181 91.963  1.00 61.52  ? 26  ASP A OD2 1 
ATOM 184  N N   . GLY A 1 27  ? 93.536  102.861 96.599  1.00 49.97  ? 27  GLY A N   1 
ATOM 185  C CA  . GLY A 1 27  ? 94.168  101.807 97.373  1.00 47.24  ? 27  GLY A CA  1 
ATOM 186  C C   . GLY A 1 27  ? 93.458  101.531 98.683  1.00 50.05  ? 27  GLY A C   1 
ATOM 187  O O   . GLY A 1 27  ? 93.333  100.377 99.099  1.00 55.74  ? 27  GLY A O   1 
ATOM 188  N N   . GLU A 1 28  ? 92.995  102.584 99.358  1.00 52.29  ? 28  GLU A N   1 
ATOM 189  C CA  . GLU A 1 28  ? 92.258  102.390 100.602 1.00 52.34  ? 28  GLU A CA  1 
ATOM 190  C C   . GLU A 1 28  ? 90.937  101.678 100.353 1.00 57.55  ? 28  GLU A C   1 
ATOM 191  O O   . GLU A 1 28  ? 90.541  100.805 101.132 1.00 64.60  ? 28  GLU A O   1 
ATOM 192  C CB  . GLU A 1 28  ? 92.025  103.732 101.292 1.00 49.55  ? 28  GLU A CB  1 
ATOM 193  C CG  . GLU A 1 28  ? 93.289  104.383 101.820 1.00 54.61  ? 28  GLU A CG  1 
ATOM 194  C CD  . GLU A 1 28  ? 93.017  105.697 102.521 1.00 66.37  ? 28  GLU A CD  1 
ATOM 195  O OE1 . GLU A 1 28  ? 91.874  106.192 102.437 1.00 62.26  ? 28  GLU A OE1 1 
ATOM 196  O OE2 . GLU A 1 28  ? 93.945  106.236 103.160 1.00 67.27  ? 28  GLU A OE2 1 
ATOM 197  N N   . LYS A 1 29  ? 90.238  102.039 99.276  1.00 54.00  ? 29  LYS A N   1 
ATOM 198  C CA  . LYS A 1 29  ? 88.982  101.372 98.957  1.00 57.98  ? 29  LYS A CA  1 
ATOM 199  C C   . LYS A 1 29  ? 89.212  99.932  98.523  1.00 56.51  ? 29  LYS A C   1 
ATOM 200  O O   . LYS A 1 29  ? 88.357  99.071  98.754  1.00 53.17  ? 29  LYS A O   1 
ATOM 201  C CB  . LYS A 1 29  ? 88.236  102.146 97.871  1.00 57.32  ? 29  LYS A CB  1 
ATOM 202  C CG  . LYS A 1 29  ? 86.830  101.639 97.608  1.00 59.64  ? 29  LYS A CG  1 
ATOM 203  C CD  . LYS A 1 29  ? 86.119  102.481 96.566  1.00 63.48  ? 29  LYS A CD  1 
ATOM 204  C CE  . LYS A 1 29  ? 84.707  101.976 96.324  1.00 64.87  ? 29  LYS A CE  1 
ATOM 205  N NZ  . LYS A 1 29  ? 83.982  102.808 95.326  1.00 61.32  ? 29  LYS A NZ  1 
ATOM 206  N N   . ALA A 1 30  ? 90.356  99.651  97.897  1.00 54.54  ? 30  ALA A N   1 
ATOM 207  C CA  . ALA A 1 30  ? 90.670  98.282  97.507  1.00 50.46  ? 30  ALA A CA  1 
ATOM 208  C C   . ALA A 1 30  ? 91.018  97.418  98.710  1.00 56.25  ? 30  ALA A C   1 
ATOM 209  O O   . ALA A 1 30  ? 90.802  96.202  98.678  1.00 63.49  ? 30  ALA A O   1 
ATOM 210  C CB  . ALA A 1 30  ? 91.819  98.273  96.499  1.00 46.49  ? 30  ALA A CB  1 
ATOM 211  N N   . ALA A 1 31  ? 91.556  98.016  99.773  1.00 58.93  ? 31  ALA A N   1 
ATOM 212  C CA  . ALA A 1 31  ? 91.913  97.261  100.968 1.00 59.10  ? 31  ALA A CA  1 
ATOM 213  C C   . ALA A 1 31  ? 90.720  96.972  101.867 1.00 60.18  ? 31  ALA A C   1 
ATOM 214  O O   . ALA A 1 31  ? 90.835  96.139  102.771 1.00 58.08  ? 31  ALA A O   1 
ATOM 215  C CB  . ALA A 1 31  ? 92.984  98.009  101.763 1.00 52.28  ? 31  ALA A CB  1 
ATOM 216  N N   . ARG A 1 32  ? 89.589  97.634  101.647 1.00 63.52  ? 32  ARG A N   1 
ATOM 217  C CA  . ARG A 1 32  ? 88.368  97.384  102.397 1.00 61.74  ? 32  ARG A CA  1 
ATOM 218  C C   . ARG A 1 32  ? 87.453  96.392  101.696 1.00 66.62  ? 32  ARG A C   1 
ATOM 219  O O   . ARG A 1 32  ? 86.310  96.206  102.126 1.00 65.48  ? 32  ARG A O   1 
ATOM 220  C CB  . ARG A 1 32  ? 87.625  98.697  102.653 1.00 58.54  ? 32  ARG A CB  1 
ATOM 221  C CG  . ARG A 1 32  ? 88.382  99.661  103.547 1.00 68.39  ? 32  ARG A CG  1 
ATOM 222  C CD  . ARG A 1 32  ? 87.572  100.908 103.868 1.00 68.71  ? 32  ARG A CD  1 
ATOM 223  N NE  . ARG A 1 32  ? 87.410  101.790 102.720 1.00 67.87  ? 32  ARG A NE  1 
ATOM 224  C CZ  . ARG A 1 32  ? 86.325  101.843 101.960 1.00 70.36  ? 32  ARG A CZ  1 
ATOM 225  N NH1 . ARG A 1 32  ? 85.277  101.071 102.197 1.00 65.80  ? 32  ARG A NH1 1 
ATOM 226  N NH2 . ARG A 1 32  ? 86.288  102.696 100.940 1.00 68.79  ? 32  ARG A NH2 1 
ATOM 227  N N   . GLU A 1 33  ? 87.927  95.762  100.627 1.00 62.86  ? 33  GLU A N   1 
ATOM 228  C CA  . GLU A 1 33  ? 87.152  94.806  99.856  1.00 58.69  ? 33  GLU A CA  1 
ATOM 229  C C   . GLU A 1 33  ? 87.763  93.418  99.974  1.00 60.14  ? 33  GLU A C   1 
ATOM 230  O O   . GLU A 1 33  ? 88.974  93.264  100.156 1.00 59.47  ? 33  GLU A O   1 
ATOM 231  C CB  . GLU A 1 33  ? 87.077  95.220  98.384  1.00 60.09  ? 33  GLU A CB  1 
ATOM 232  C CG  . GLU A 1 33  ? 86.279  96.490  98.145  1.00 66.30  ? 33  GLU A CG  1 
ATOM 233  C CD  . GLU A 1 33  ? 86.446  97.029  96.741  1.00 70.88  ? 33  GLU A CD  1 
ATOM 234  O OE1 . GLU A 1 33  ? 87.480  96.732  96.108  1.00 68.33  ? 33  GLU A OE1 1 
ATOM 235  O OE2 . GLU A 1 33  ? 85.544  97.754  96.271  1.00 70.78  ? 33  GLU A OE2 1 
ATOM 236  N N   . VAL A 1 34  ? 86.906  92.408  99.867  1.00 53.72  ? 34  VAL A N   1 
ATOM 237  C CA  . VAL A 1 34  ? 87.292  91.012  100.023 1.00 44.99  ? 34  VAL A CA  1 
ATOM 238  C C   . VAL A 1 34  ? 87.466  90.404  98.642  1.00 50.18  ? 34  VAL A C   1 
ATOM 239  O O   . VAL A 1 34  ? 86.570  90.499  97.795  1.00 55.09  ? 34  VAL A O   1 
ATOM 240  C CB  . VAL A 1 34  ? 86.245  90.237  100.836 1.00 46.78  ? 34  VAL A CB  1 
ATOM 241  C CG1 . VAL A 1 34  ? 86.670  88.796  101.001 1.00 48.26  ? 34  VAL A CG1 1 
ATOM 242  C CG2 . VAL A 1 34  ? 86.028  90.900  102.182 1.00 44.81  ? 34  VAL A CG2 1 
ATOM 243  N N   . LYS A 1 35  ? 88.615  89.782  98.411  1.00 48.42  ? 35  LYS A N   1 
ATOM 244  C CA  . LYS A 1 35  ? 88.929  89.145  97.140  1.00 45.87  ? 35  LYS A CA  1 
ATOM 245  C C   . LYS A 1 35  ? 88.985  87.639  97.342  1.00 47.81  ? 35  LYS A C   1 
ATOM 246  O O   . LYS A 1 35  ? 89.750  87.151  98.178  1.00 59.80  ? 35  LYS A O   1 
ATOM 247  C CB  . LYS A 1 35  ? 90.251  89.672  96.587  1.00 47.69  ? 35  LYS A CB  1 
ATOM 248  C CG  . LYS A 1 35  ? 90.221  91.154  96.285  1.00 53.32  ? 35  LYS A CG  1 
ATOM 249  C CD  . LYS A 1 35  ? 91.479  91.607  95.577  1.00 57.54  ? 35  LYS A CD  1 
ATOM 250  C CE  . LYS A 1 35  ? 91.384  93.072  95.187  1.00 60.54  ? 35  LYS A CE  1 
ATOM 251  N NZ  . LYS A 1 35  ? 92.590  93.523  94.440  1.00 56.81  ? 35  LYS A NZ  1 
ATOM 252  N N   . LEU A 1 36  ? 88.183  86.908  96.572  1.00 34.64  ? 36  LEU A N   1 
ATOM 253  C CA  . LEU A 1 36  ? 88.062  85.463  96.704  1.00 37.20  ? 36  LEU A CA  1 
ATOM 254  C C   . LEU A 1 36  ? 88.432  84.790  95.392  1.00 42.64  ? 36  LEU A C   1 
ATOM 255  O O   . LEU A 1 36  ? 87.888  85.133  94.339  1.00 49.59  ? 36  LEU A O   1 
ATOM 256  C CB  . LEU A 1 36  ? 86.638  85.072  97.103  1.00 40.03  ? 36  LEU A CB  1 
ATOM 257  C CG  . LEU A 1 36  ? 86.077  85.682  98.385  1.00 36.29  ? 36  LEU A CG  1 
ATOM 258  C CD1 . LEU A 1 36  ? 84.609  85.355  98.520  1.00 44.41  ? 36  LEU A CD1 1 
ATOM 259  C CD2 . LEU A 1 36  ? 86.841  85.186  99.591  1.00 38.25  ? 36  LEU A CD2 1 
ATOM 260  N N   . LEU A 1 37  ? 89.349  83.830  95.459  1.00 42.24  ? 37  LEU A N   1 
ATOM 261  C CA  . LEU A 1 37  ? 89.710  83.010  94.309  1.00 37.81  ? 37  LEU A CA  1 
ATOM 262  C C   . LEU A 1 37  ? 88.843  81.760  94.337  1.00 42.11  ? 37  LEU A C   1 
ATOM 263  O O   . LEU A 1 37  ? 89.012  80.900  95.204  1.00 55.79  ? 37  LEU A O   1 
ATOM 264  C CB  . LEU A 1 37  ? 91.192  82.648  94.333  1.00 43.01  ? 37  LEU A CB  1 
ATOM 265  C CG  . LEU A 1 37  ? 91.656  81.695  93.230  1.00 42.06  ? 37  LEU A CG  1 
ATOM 266  C CD1 . LEU A 1 37  ? 91.426  82.303  91.861  1.00 44.76  ? 37  LEU A CD1 1 
ATOM 267  C CD2 . LEU A 1 37  ? 93.113  81.321  93.418  1.00 37.81  ? 37  LEU A CD2 1 
ATOM 268  N N   . LEU A 1 38  ? 87.914  81.661  93.395  1.00 50.68  ? 38  LEU A N   1 
ATOM 269  C CA  . LEU A 1 38  ? 86.975  80.548  93.349  1.00 49.53  ? 38  LEU A CA  1 
ATOM 270  C C   . LEU A 1 38  ? 87.576  79.433  92.505  1.00 55.25  ? 38  LEU A C   1 
ATOM 271  O O   . LEU A 1 38  ? 87.780  79.597  91.299  1.00 62.20  ? 38  LEU A O   1 
ATOM 272  C CB  . LEU A 1 38  ? 85.633  81.005  92.789  1.00 43.45  ? 38  LEU A CB  1 
ATOM 273  C CG  . LEU A 1 38  ? 84.585  79.914  92.602  1.00 60.00  ? 38  LEU A CG  1 
ATOM 274  C CD1 . LEU A 1 38  ? 84.327  79.189  93.908  1.00 61.34  ? 38  LEU A CD1 1 
ATOM 275  C CD2 . LEU A 1 38  ? 83.308  80.519  92.062  1.00 65.22  ? 38  LEU A CD2 1 
ATOM 276  N N   . LEU A 1 39  ? 87.856  78.301  93.139  1.00 53.98  ? 39  LEU A N   1 
ATOM 277  C CA  . LEU A 1 39  ? 88.432  77.142  92.480  1.00 48.21  ? 39  LEU A CA  1 
ATOM 278  C C   . LEU A 1 39  ? 87.504  75.947  92.630  1.00 56.13  ? 39  LEU A C   1 
ATOM 279  O O   . LEU A 1 39  ? 86.511  75.984  93.359  1.00 60.49  ? 39  LEU A O   1 
ATOM 280  C CB  . LEU A 1 39  ? 89.816  76.814  93.050  1.00 49.76  ? 39  LEU A CB  1 
ATOM 281  C CG  . LEU A 1 39  ? 90.901  77.856  92.791  1.00 51.49  ? 39  LEU A CG  1 
ATOM 282  C CD1 . LEU A 1 39  ? 92.220  77.398  93.365  1.00 53.35  ? 39  LEU A CD1 1 
ATOM 283  C CD2 . LEU A 1 39  ? 91.032  78.110  91.307  1.00 52.72  ? 39  LEU A CD2 1 
ATOM 284  N N   . GLY A 1 40  ? 87.838  74.887  91.921  1.00 70.23  ? 40  GLY A N   1 
ATOM 285  C CA  . GLY A 1 40  ? 87.048  73.673  91.949  1.00 69.52  ? 40  GLY A CA  1 
ATOM 286  C C   . GLY A 1 40  ? 87.224  72.908  90.655  1.00 73.45  ? 40  GLY A C   1 
ATOM 287  O O   . GLY A 1 40  ? 87.969  73.306  89.764  1.00 76.39  ? 40  GLY A O   1 
ATOM 288  N N   . ALA A 1 41  ? 86.508  71.795  90.569  1.00 90.73  ? 41  ALA A N   1 
ATOM 289  C CA  . ALA A 1 41  ? 86.548  70.921  89.408  1.00 91.88  ? 41  ALA A CA  1 
ATOM 290  C C   . ALA A 1 41  ? 85.232  71.010  88.645  1.00 94.92  ? 41  ALA A C   1 
ATOM 291  O O   . ALA A 1 41  ? 84.280  71.668  89.070  1.00 96.91  ? 41  ALA A O   1 
ATOM 292  C CB  . ALA A 1 41  ? 86.837  69.474  89.824  1.00 88.99  ? 41  ALA A CB  1 
ATOM 293  N N   . GLY A 1 42  ? 85.192  70.337  87.499  1.00 99.21  ? 42  GLY A N   1 
ATOM 294  C CA  . GLY A 1 42  ? 83.988  70.350  86.687  1.00 99.21  ? 42  GLY A CA  1 
ATOM 295  C C   . GLY A 1 42  ? 82.858  69.586  87.356  1.00 102.57 ? 42  GLY A C   1 
ATOM 296  O O   . GLY A 1 42  ? 83.071  68.565  88.013  1.00 101.61 ? 42  GLY A O   1 
ATOM 297  N N   . GLU A 1 43  ? 81.637  70.097  87.179  1.00 108.02 ? 43  GLU A N   1 
ATOM 298  C CA  . GLU A 1 43  ? 80.429  69.490  87.742  1.00 107.73 ? 43  GLU A CA  1 
ATOM 299  C C   . GLU A 1 43  ? 80.535  69.338  89.258  1.00 109.96 ? 43  GLU A C   1 
ATOM 300  O O   . GLU A 1 43  ? 80.086  68.346  89.835  1.00 110.73 ? 43  GLU A O   1 
ATOM 301  C CB  . GLU A 1 43  ? 80.126  68.143  87.079  1.00 106.50 ? 43  GLU A CB  1 
ATOM 302  N N   . SER A 1 44  ? 81.138  70.331  89.909  1.00 101.76 ? 44  SER A N   1 
ATOM 303  C CA  . SER A 1 44  ? 81.295  70.341  91.358  1.00 100.26 ? 44  SER A CA  1 
ATOM 304  C C   . SER A 1 44  ? 80.384  71.353  92.040  1.00 101.84 ? 44  SER A C   1 
ATOM 305  O O   . SER A 1 44  ? 80.553  71.618  93.234  1.00 101.35 ? 44  SER A O   1 
ATOM 306  C CB  . SER A 1 44  ? 82.754  70.615  91.728  1.00 96.11  ? 44  SER A CB  1 
ATOM 307  O OG  . SER A 1 44  ? 83.186  71.859  91.207  1.00 97.51  ? 44  SER A OG  1 
ATOM 308  N N   . GLY A 1 45  ? 79.423  71.922  91.317  1.00 102.93 ? 45  GLY A N   1 
ATOM 309  C CA  . GLY A 1 45  ? 78.555  72.933  91.882  1.00 102.59 ? 45  GLY A CA  1 
ATOM 310  C C   . GLY A 1 45  ? 79.158  74.314  91.976  1.00 102.61 ? 45  GLY A C   1 
ATOM 311  O O   . GLY A 1 45  ? 78.580  75.179  92.645  1.00 101.33 ? 45  GLY A O   1 
ATOM 312  N N   . LYS A 1 46  ? 80.304  74.548  91.333  1.00 93.60  ? 46  LYS A N   1 
ATOM 313  C CA  . LYS A 1 46  ? 80.941  75.858  91.397  1.00 94.77  ? 46  LYS A CA  1 
ATOM 314  C C   . LYS A 1 46  ? 80.049  76.936  90.795  1.00 93.85  ? 46  LYS A C   1 
ATOM 315  O O   . LYS A 1 46  ? 79.923  78.033  91.353  1.00 94.18  ? 46  LYS A O   1 
ATOM 316  C CB  . LYS A 1 46  ? 82.287  75.818  90.679  1.00 90.50  ? 46  LYS A CB  1 
ATOM 317  C CG  . LYS A 1 46  ? 83.088  77.097  90.791  1.00 86.63  ? 46  LYS A CG  1 
ATOM 318  C CD  . LYS A 1 46  ? 84.209  77.157  89.763  1.00 90.43  ? 46  LYS A CD  1 
ATOM 319  C CE  . LYS A 1 46  ? 85.137  75.959  89.860  1.00 93.01  ? 46  LYS A CE  1 
ATOM 320  N NZ  . LYS A 1 46  ? 84.761  74.868  88.917  1.00 91.96  ? 46  LYS A NZ  1 
ATOM 321  N N   . ASN A 1 47  ? 79.421  76.642  89.654  1.00 103.89 ? 47  ASN A N   1 
ATOM 322  C CA  . ASN A 1 47  ? 78.535  77.613  89.022  1.00 105.25 ? 47  ASN A CA  1 
ATOM 323  C C   . ASN A 1 47  ? 77.286  77.864  89.856  1.00 106.14 ? 47  ASN A C   1 
ATOM 324  O O   . ASN A 1 47  ? 76.700  78.950  89.779  1.00 104.20 ? 47  ASN A O   1 
ATOM 325  C CB  . ASN A 1 47  ? 78.155  77.139  87.621  1.00 104.77 ? 47  ASN A CB  1 
ATOM 326  C CG  . ASN A 1 47  ? 79.361  76.953  86.725  1.00 106.24 ? 47  ASN A CG  1 
ATOM 327  O OD1 . ASN A 1 47  ? 79.611  75.859  86.219  1.00 105.17 ? 47  ASN A OD1 1 
ATOM 328  N ND2 . ASN A 1 47  ? 80.119  78.025  86.524  1.00 103.96 ? 47  ASN A ND2 1 
ATOM 329  N N   . THR A 1 48  ? 76.858  76.878  90.648  1.00 111.95 ? 48  THR A N   1 
ATOM 330  C CA  . THR A 1 48  ? 75.716  77.094  91.529  1.00 111.13 ? 48  THR A CA  1 
ATOM 331  C C   . THR A 1 48  ? 76.050  78.082  92.638  1.00 111.62 ? 48  THR A C   1 
ATOM 332  O O   . THR A 1 48  ? 75.183  78.855  93.059  1.00 111.40 ? 48  THR A O   1 
ATOM 333  C CB  . THR A 1 48  ? 75.247  75.767  92.125  1.00 107.00 ? 48  THR A CB  1 
ATOM 334  N N   . ILE A 1 49  ? 77.294  78.068  93.123  1.00 107.81 ? 49  ILE A N   1 
ATOM 335  C CA  . ILE A 1 49  ? 77.709  79.020  94.150  1.00 105.08 ? 49  ILE A CA  1 
ATOM 336  C C   . ILE A 1 49  ? 77.638  80.443  93.613  1.00 104.14 ? 49  ILE A C   1 
ATOM 337  O O   . ILE A 1 49  ? 77.191  81.364  94.307  1.00 102.28 ? 49  ILE A O   1 
ATOM 338  C CB  . ILE A 1 49  ? 79.120  78.671  94.658  1.00 103.27 ? 49  ILE A CB  1 
ATOM 339  C CG1 . ILE A 1 49  ? 79.136  77.259  95.241  1.00 102.74 ? 49  ILE A CG1 1 
ATOM 340  C CG2 . ILE A 1 49  ? 79.584  79.679  95.694  1.00 102.51 ? 49  ILE A CG2 1 
ATOM 341  C CD1 . ILE A 1 49  ? 78.161  77.060  96.375  1.00 102.24 ? 49  ILE A CD1 1 
ATOM 342  N N   . VAL A 1 50  ? 78.082  80.646  92.371  1.00 105.02 ? 50  VAL A N   1 
ATOM 343  C CA  . VAL A 1 50  ? 78.028  81.973  91.765  1.00 106.66 ? 50  VAL A CA  1 
ATOM 344  C C   . VAL A 1 50  ? 76.584  82.425  91.600  1.00 109.80 ? 50  VAL A C   1 
ATOM 345  O O   . VAL A 1 50  ? 76.258  83.602  91.802  1.00 111.45 ? 50  VAL A O   1 
ATOM 346  C CB  . VAL A 1 50  ? 78.778  81.978  90.421  1.00 105.65 ? 50  VAL A CB  1 
ATOM 347  C CG1 . VAL A 1 50  ? 78.887  83.393  89.880  1.00 105.52 ? 50  VAL A CG1 1 
ATOM 348  C CG2 . VAL A 1 50  ? 80.148  81.354  90.581  1.00 105.89 ? 50  VAL A CG2 1 
ATOM 349  N N   . LYS A 1 51  ? 75.695  81.501  91.226  1.00 113.50 ? 51  LYS A N   1 
ATOM 350  C CA  . LYS A 1 51  ? 74.283  81.845  91.088  1.00 114.09 ? 51  LYS A CA  1 
ATOM 351  C C   . LYS A 1 51  ? 73.678  82.273  92.418  1.00 115.15 ? 51  LYS A C   1 
ATOM 352  O O   . LYS A 1 51  ? 72.743  83.082  92.442  1.00 114.07 ? 51  LYS A O   1 
ATOM 353  C CB  . LYS A 1 51  ? 73.508  80.661  90.509  1.00 112.58 ? 51  LYS A CB  1 
ATOM 354  N N   . GLN A 1 52  ? 74.192  81.748  93.529  1.00 108.60 ? 52  GLN A N   1 
ATOM 355  C CA  . GLN A 1 52  ? 73.723  82.147  94.849  1.00 106.57 ? 52  GLN A CA  1 
ATOM 356  C C   . GLN A 1 52  ? 74.404  83.409  95.358  1.00 108.14 ? 52  GLN A C   1 
ATOM 357  O O   . GLN A 1 52  ? 73.984  83.946  96.388  1.00 106.93 ? 52  GLN A O   1 
ATOM 358  C CB  . GLN A 1 52  ? 73.945  81.009  95.848  1.00 105.96 ? 52  GLN A CB  1 
ATOM 359  C CG  . GLN A 1 52  ? 73.261  79.708  95.468  1.00 108.33 ? 52  GLN A CG  1 
ATOM 360  C CD  . GLN A 1 52  ? 73.695  78.546  96.338  1.00 109.76 ? 52  GLN A CD  1 
ATOM 361  O OE1 . GLN A 1 52  ? 74.502  78.709  97.252  1.00 110.75 ? 52  GLN A OE1 1 
ATOM 362  N NE2 . GLN A 1 52  ? 73.165  77.363  96.054  1.00 108.73 ? 52  GLN A NE2 1 
ATOM 363  N N   . MET A 1 53  ? 75.435  83.890  94.669  1.00 101.80 ? 53  MET A N   1 
ATOM 364  C CA  . MET A 1 53  ? 76.182  85.079  95.058  1.00 98.19  ? 53  MET A CA  1 
ATOM 365  C C   . MET A 1 53  ? 76.204  86.104  93.930  1.00 98.43  ? 53  MET A C   1 
ATOM 366  O O   . MET A 1 53  ? 77.238  86.702  93.629  1.00 95.46  ? 53  MET A O   1 
ATOM 367  C CB  . MET A 1 53  ? 77.603  84.714  95.476  1.00 95.46  ? 53  MET A CB  1 
ATOM 368  C CG  . MET A 1 53  ? 77.679  83.721  96.622  1.00 97.10  ? 53  MET A CG  1 
ATOM 369  S SD  . MET A 1 53  ? 79.376  83.284  97.041  1.00 101.11 ? 53  MET A SD  1 
ATOM 370  C CE  . MET A 1 53  ? 79.103  82.140  98.387  1.00 94.67  ? 53  MET A CE  1 
ATOM 371  N N   . LYS A 1 54  ? 75.060  86.314  93.288  1.00 109.79 ? 54  LYS A N   1 
ATOM 372  C CA  . LYS A 1 54  ? 74.965  87.274  92.195  1.00 108.51 ? 54  LYS A CA  1 
ATOM 373  C C   . LYS A 1 54  ? 74.708  88.681  92.725  1.00 107.08 ? 54  LYS A C   1 
ATOM 374  O O   . LYS A 1 54  ? 73.811  88.891  93.542  1.00 104.99 ? 54  LYS A O   1 
ATOM 375  C CB  . LYS A 1 54  ? 73.861  86.869  91.217  1.00 107.03 ? 54  LYS A CB  1 
ATOM 376  N N   . THR A 1 182 ? 85.064  85.913  78.839  1.00 52.81  ? 182 THR A N   1 
ATOM 377  C CA  . THR A 1 182 ? 86.467  86.113  78.497  1.00 59.14  ? 182 THR A CA  1 
ATOM 378  C C   . THR A 1 182 ? 87.343  85.046  79.149  1.00 62.04  ? 182 THR A C   1 
ATOM 379  O O   . THR A 1 182 ? 87.053  83.854  79.058  1.00 55.60  ? 182 THR A O   1 
ATOM 380  C CB  . THR A 1 182 ? 86.956  87.506  78.929  1.00 51.50  ? 182 THR A CB  1 
ATOM 381  N N   . GLY A 1 183 ? 88.419  85.479  79.801  1.00 53.55  ? 183 GLY A N   1 
ATOM 382  C CA  . GLY A 1 183 ? 89.312  84.548  80.459  1.00 45.54  ? 183 GLY A CA  1 
ATOM 383  C C   . GLY A 1 183 ? 88.994  84.361  81.926  1.00 51.64  ? 183 GLY A C   1 
ATOM 384  O O   . GLY A 1 183 ? 88.914  83.229  82.409  1.00 59.67  ? 183 GLY A O   1 
ATOM 385  N N   . ILE A 1 184 ? 88.813  85.463  82.647  1.00 43.40  ? 184 ILE A N   1 
ATOM 386  C CA  . ILE A 1 184 ? 88.532  85.435  84.075  1.00 44.36  ? 184 ILE A CA  1 
ATOM 387  C C   . ILE A 1 184 ? 87.186  86.107  84.304  1.00 47.57  ? 184 ILE A C   1 
ATOM 388  O O   . ILE A 1 184 ? 86.869  87.114  83.662  1.00 55.07  ? 184 ILE A O   1 
ATOM 389  C CB  . ILE A 1 184 ? 89.650  86.114  84.897  1.00 43.66  ? 184 ILE A CB  1 
ATOM 390  C CG1 . ILE A 1 184 ? 89.345  86.036  86.392  1.00 40.94  ? 184 ILE A CG1 1 
ATOM 391  C CG2 . ILE A 1 184 ? 89.842  87.560  84.472  1.00 46.69  ? 184 ILE A CG2 1 
ATOM 392  C CD1 . ILE A 1 184 ? 90.398  86.667  87.255  1.00 41.19  ? 184 ILE A CD1 1 
ATOM 393  N N   . VAL A 1 185 ? 86.386  85.535  85.198  1.00 46.38  ? 185 VAL A N   1 
ATOM 394  C CA  . VAL A 1 185 ? 85.057  86.047  85.511  1.00 47.12  ? 185 VAL A CA  1 
ATOM 395  C C   . VAL A 1 185 ? 85.078  86.578  86.935  1.00 48.36  ? 185 VAL A C   1 
ATOM 396  O O   . VAL A 1 185 ? 85.322  85.822  87.883  1.00 60.83  ? 185 VAL A O   1 
ATOM 397  C CB  . VAL A 1 185 ? 83.980  84.967  85.342  1.00 48.46  ? 185 VAL A CB  1 
ATOM 398  C CG1 . VAL A 1 185 ? 82.612  85.537  85.652  1.00 51.13  ? 185 VAL A CG1 1 
ATOM 399  C CG2 . VAL A 1 185 ? 84.018  84.398  83.939  1.00 46.07  ? 185 VAL A CG2 1 
ATOM 400  N N   . GLU A 1 186 ? 84.815  87.870  87.088  1.00 52.12  ? 186 GLU A N   1 
ATOM 401  C CA  . GLU A 1 186 ? 84.777  88.522  88.388  1.00 52.61  ? 186 GLU A CA  1 
ATOM 402  C C   . GLU A 1 186 ? 83.336  88.844  88.749  1.00 56.25  ? 186 GLU A C   1 
ATOM 403  O O   . GLU A 1 186 ? 82.595  89.393  87.928  1.00 59.57  ? 186 GLU A O   1 
ATOM 404  C CB  . GLU A 1 186 ? 85.619  89.797  88.384  1.00 50.17  ? 186 GLU A CB  1 
ATOM 405  C CG  . GLU A 1 186 ? 85.659  90.516  89.718  1.00 53.23  ? 186 GLU A CG  1 
ATOM 406  C CD  . GLU A 1 186 ? 86.541  91.745  89.687  1.00 64.82  ? 186 GLU A CD  1 
ATOM 407  O OE1 . GLU A 1 186 ? 87.142  92.018  88.627  1.00 62.98  ? 186 GLU A OE1 1 
ATOM 408  O OE2 . GLU A 1 186 ? 86.631  92.442  90.719  1.00 62.20  ? 186 GLU A OE2 1 
ATOM 409  N N   . THR A 1 187 ? 82.942  88.500  89.972  1.00 58.86  ? 187 THR A N   1 
ATOM 410  C CA  . THR A 1 187 ? 81.593  88.737  90.465  1.00 54.85  ? 187 THR A CA  1 
ATOM 411  C C   . THR A 1 187 ? 81.666  89.615  91.704  1.00 58.33  ? 187 THR A C   1 
ATOM 412  O O   . THR A 1 187 ? 82.399  89.302  92.646  1.00 63.01  ? 187 THR A O   1 
ATOM 413  C CB  . THR A 1 187 ? 80.885  87.422  90.794  1.00 56.56  ? 187 THR A CB  1 
ATOM 414  O OG1 . THR A 1 187 ? 80.900  86.570  89.643  1.00 59.66  ? 187 THR A OG1 1 
ATOM 415  C CG2 . THR A 1 187 ? 79.444  87.683  91.196  1.00 56.35  ? 187 THR A CG2 1 
ATOM 416  N N   . HIS A 1 188 ? 80.907  90.706  91.702  1.00 60.55  ? 188 HIS A N   1 
ATOM 417  C CA  . HIS A 1 188 ? 80.843  91.630  92.825  1.00 52.78  ? 188 HIS A CA  1 
ATOM 418  C C   . HIS A 1 188 ? 79.511  91.469  93.539  1.00 56.10  ? 188 HIS A C   1 
ATOM 419  O O   . HIS A 1 188 ? 78.461  91.403  92.894  1.00 63.73  ? 188 HIS A O   1 
ATOM 420  C CB  . HIS A 1 188 ? 81.001  93.081  92.371  1.00 53.79  ? 188 HIS A CB  1 
ATOM 421  C CG  . HIS A 1 188 ? 82.293  93.367  91.675  1.00 59.33  ? 188 HIS A CG  1 
ATOM 422  N ND1 . HIS A 1 188 ? 82.535  92.991  90.373  1.00 65.59  ? 188 HIS A ND1 1 
ATOM 423  C CD2 . HIS A 1 188 ? 83.407  94.009  92.096  1.00 60.86  ? 188 HIS A CD2 1 
ATOM 424  C CE1 . HIS A 1 188 ? 83.747  93.382  90.023  1.00 64.89  ? 188 HIS A CE1 1 
ATOM 425  N NE2 . HIS A 1 188 ? 84.298  94.000  91.051  1.00 67.14  ? 188 HIS A NE2 1 
ATOM 426  N N   . PHE A 1 189 ? 79.559  91.402  94.865  1.00 57.02  ? 189 PHE A N   1 
ATOM 427  C CA  . PHE A 1 189 ? 78.350  91.430  95.670  1.00 58.03  ? 189 PHE A CA  1 
ATOM 428  C C   . PHE A 1 189 ? 78.702  91.979  97.042  1.00 62.09  ? 189 PHE A C   1 
ATOM 429  O O   . PHE A 1 189 ? 79.834  91.839  97.511  1.00 63.59  ? 189 PHE A O   1 
ATOM 430  C CB  . PHE A 1 189 ? 77.697  90.046  95.782  1.00 53.48  ? 189 PHE A CB  1 
ATOM 431  C CG  . PHE A 1 189 ? 78.558  89.011  96.445  1.00 57.10  ? 189 PHE A CG  1 
ATOM 432  C CD1 . PHE A 1 189 ? 79.520  88.324  95.724  1.00 61.36  ? 189 PHE A CD1 1 
ATOM 433  C CD2 . PHE A 1 189 ? 78.386  88.701  97.782  1.00 56.03  ? 189 PHE A CD2 1 
ATOM 434  C CE1 . PHE A 1 189 ? 80.306  87.366  96.328  1.00 57.51  ? 189 PHE A CE1 1 
ATOM 435  C CE2 . PHE A 1 189 ? 79.170  87.742  98.391  1.00 58.84  ? 189 PHE A CE2 1 
ATOM 436  C CZ  . PHE A 1 189 ? 80.129  87.072  97.662  1.00 55.21  ? 189 PHE A CZ  1 
ATOM 437  N N   . THR A 1 190 ? 77.725  92.621  97.673  1.00 67.37  ? 190 THR A N   1 
ATOM 438  C CA  . THR A 1 190 ? 77.905  93.244  98.974  1.00 61.11  ? 190 THR A CA  1 
ATOM 439  C C   . THR A 1 190 ? 77.000  92.547  99.976  1.00 60.42  ? 190 THR A C   1 
ATOM 440  O O   . THR A 1 190 ? 75.809  92.353  99.711  1.00 59.58  ? 190 THR A O   1 
ATOM 441  C CB  . THR A 1 190 ? 77.589  94.740  98.922  1.00 61.56  ? 190 THR A CB  1 
ATOM 442  O OG1 . THR A 1 190 ? 78.423  95.370  97.942  1.00 62.19  ? 190 THR A OG1 1 
ATOM 443  C CG2 . THR A 1 190 ? 77.840  95.386  100.271 1.00 60.62  ? 190 THR A CG2 1 
ATOM 444  N N   . PHE A 1 191 ? 77.565  92.169  101.118 1.00 58.71  ? 191 PHE A N   1 
ATOM 445  C CA  . PHE A 1 191 ? 76.823  91.458  102.151 1.00 56.76  ? 191 PHE A CA  1 
ATOM 446  C C   . PHE A 1 191 ? 77.222  92.025  103.502 1.00 61.03  ? 191 PHE A C   1 
ATOM 447  O O   . PHE A 1 191 ? 78.381  91.904  103.907 1.00 65.40  ? 191 PHE A O   1 
ATOM 448  C CB  . PHE A 1 191 ? 77.098  89.954  102.087 1.00 53.33  ? 191 PHE A CB  1 
ATOM 449  C CG  . PHE A 1 191 ? 76.156  89.130  102.910 1.00 57.82  ? 191 PHE A CG  1 
ATOM 450  C CD1 . PHE A 1 191 ? 74.921  88.763  102.409 1.00 60.50  ? 191 PHE A CD1 1 
ATOM 451  C CD2 . PHE A 1 191 ? 76.506  88.718  104.181 1.00 60.70  ? 191 PHE A CD2 1 
ATOM 452  C CE1 . PHE A 1 191 ? 74.051  88.004  103.161 1.00 58.87  ? 191 PHE A CE1 1 
ATOM 453  C CE2 . PHE A 1 191 ? 75.640  87.959  104.938 1.00 61.48  ? 191 PHE A CE2 1 
ATOM 454  C CZ  . PHE A 1 191 ? 74.411  87.602  104.427 1.00 59.86  ? 191 PHE A CZ  1 
ATOM 455  N N   . LYS A 1 192 ? 76.263  92.649  104.188 1.00 60.65  ? 192 LYS A N   1 
ATOM 456  C CA  . LYS A 1 192 ? 76.466  93.213  105.522 1.00 59.99  ? 192 LYS A CA  1 
ATOM 457  C C   . LYS A 1 192 ? 77.616  94.223  105.528 1.00 56.33  ? 192 LYS A C   1 
ATOM 458  O O   . LYS A 1 192 ? 78.590  94.097  106.271 1.00 65.04  ? 192 LYS A O   1 
ATOM 459  C CB  . LYS A 1 192 ? 76.693  92.106  106.556 1.00 55.34  ? 192 LYS A CB  1 
ATOM 460  C CG  . LYS A 1 192 ? 75.487  91.208  106.762 1.00 56.50  ? 192 LYS A CG  1 
ATOM 461  C CD  . LYS A 1 192 ? 75.726  90.202  107.871 1.00 60.81  ? 192 LYS A CD  1 
ATOM 462  C CE  . LYS A 1 192 ? 74.490  89.354  108.110 1.00 64.05  ? 192 LYS A CE  1 
ATOM 463  N NZ  . LYS A 1 192 ? 74.681  88.394  109.231 1.00 64.02  ? 192 LYS A NZ  1 
ATOM 464  N N   . ASP A 1 193 ? 77.477  95.237  104.672 1.00 53.60  ? 193 ASP A N   1 
ATOM 465  C CA  . ASP A 1 193 ? 78.424  96.350  104.587 1.00 58.58  ? 193 ASP A CA  1 
ATOM 466  C C   . ASP A 1 193 ? 79.837  95.873  104.270 1.00 59.82  ? 193 ASP A C   1 
ATOM 467  O O   . ASP A 1 193 ? 80.821  96.475  104.705 1.00 63.73  ? 193 ASP A O   1 
ATOM 468  C CB  . ASP A 1 193 ? 78.421  97.184  105.872 1.00 65.46  ? 193 ASP A CB  1 
ATOM 469  C CG  . ASP A 1 193 ? 77.059  97.770  106.185 1.00 70.68  ? 193 ASP A CG  1 
ATOM 470  O OD1 . ASP A 1 193 ? 76.155  97.002  106.577 1.00 70.60  ? 193 ASP A OD1 1 
ATOM 471  O OD2 . ASP A 1 193 ? 76.892  98.999  106.042 1.00 66.72  ? 193 ASP A OD2 1 
ATOM 472  N N   . LEU A 1 194 ? 79.949  94.790  103.507 1.00 55.32  ? 194 LEU A N   1 
ATOM 473  C CA  . LEU A 1 194 ? 81.238  94.249  103.102 1.00 55.16  ? 194 LEU A CA  1 
ATOM 474  C C   . LEU A 1 194 ? 81.158  93.875  101.632 1.00 58.32  ? 194 LEU A C   1 
ATOM 475  O O   . LEU A 1 194 ? 80.227  93.178  101.222 1.00 59.98  ? 194 LEU A O   1 
ATOM 476  C CB  . LEU A 1 194 ? 81.614  93.030  103.950 1.00 49.57  ? 194 LEU A CB  1 
ATOM 477  C CG  . LEU A 1 194 ? 83.024  92.470  103.781 1.00 53.33  ? 194 LEU A CG  1 
ATOM 478  C CD1 . LEU A 1 194 ? 84.056  93.554  104.022 1.00 55.96  ? 194 LEU A CD1 1 
ATOM 479  C CD2 . LEU A 1 194 ? 83.245  91.302  104.723 1.00 51.26  ? 194 LEU A CD2 1 
ATOM 480  N N   . HIS A 1 195 ? 82.128  94.330  100.847 1.00 53.97  ? 195 HIS A N   1 
ATOM 481  C CA  . HIS A 1 195 ? 82.119  94.131  99.405  1.00 57.76  ? 195 HIS A CA  1 
ATOM 482  C C   . HIS A 1 195 ? 83.025  92.964  99.046  1.00 60.66  ? 195 HIS A C   1 
ATOM 483  O O   . HIS A 1 195 ? 84.206  92.955  99.404  1.00 61.68  ? 195 HIS A O   1 
ATOM 484  C CB  . HIS A 1 195 ? 82.572  95.394  98.675  1.00 58.83  ? 195 HIS A CB  1 
ATOM 485  C CG  . HIS A 1 195 ? 82.405  95.325  97.189  1.00 63.18  ? 195 HIS A CG  1 
ATOM 486  N ND1 . HIS A 1 195 ? 81.169  95.281  96.581  1.00 65.24  ? 195 HIS A ND1 1 
ATOM 487  C CD2 . HIS A 1 195 ? 83.317  95.292  96.189  1.00 63.89  ? 195 HIS A CD2 1 
ATOM 488  C CE1 . HIS A 1 195 ? 81.327  95.227  95.271  1.00 58.93  ? 195 HIS A CE1 1 
ATOM 489  N NE2 . HIS A 1 195 ? 82.621  95.231  95.007  1.00 64.15  ? 195 HIS A NE2 1 
ATOM 490  N N   . PHE A 1 196 ? 82.470  91.991  98.332  1.00 55.65  ? 196 PHE A N   1 
ATOM 491  C CA  . PHE A 1 196 ? 83.187  90.788  97.935  1.00 49.58  ? 196 PHE A CA  1 
ATOM 492  C C   . PHE A 1 196 ? 83.457  90.813  96.440  1.00 50.07  ? 196 PHE A C   1 
ATOM 493  O O   . PHE A 1 196 ? 82.562  91.120  95.648  1.00 56.13  ? 196 PHE A O   1 
ATOM 494  C CB  . PHE A 1 196 ? 82.391  89.530  98.280  1.00 48.64  ? 196 PHE A CB  1 
ATOM 495  C CG  . PHE A 1 196 ? 82.224  89.291  99.748  1.00 49.18  ? 196 PHE A CG  1 
ATOM 496  C CD1 . PHE A 1 196 ? 81.186  89.880  100.445 1.00 46.95  ? 196 PHE A CD1 1 
ATOM 497  C CD2 . PHE A 1 196 ? 83.086  88.450  100.426 1.00 51.98  ? 196 PHE A CD2 1 
ATOM 498  C CE1 . PHE A 1 196 ? 81.025  89.649  101.790 1.00 50.47  ? 196 PHE A CE1 1 
ATOM 499  C CE2 . PHE A 1 196 ? 82.926  88.216  101.770 1.00 52.44  ? 196 PHE A CE2 1 
ATOM 500  C CZ  . PHE A 1 196 ? 81.895  88.816  102.454 1.00 52.22  ? 196 PHE A CZ  1 
ATOM 501  N N   . LYS A 1 197 ? 84.686  90.482  96.063  1.00 53.14  ? 197 LYS A N   1 
ATOM 502  C CA  . LYS A 1 197 ? 85.077  90.297  94.672  1.00 52.21  ? 197 LYS A CA  1 
ATOM 503  C C   . LYS A 1 197 ? 85.504  88.845  94.525  1.00 55.32  ? 197 LYS A C   1 
ATOM 504  O O   . LYS A 1 197 ? 86.542  88.444  95.059  1.00 65.04  ? 197 LYS A O   1 
ATOM 505  C CB  . LYS A 1 197 ? 86.204  91.248  94.278  1.00 55.58  ? 197 LYS A CB  1 
ATOM 506  C CG  . LYS A 1 197 ? 85.804  92.709  94.261  1.00 58.56  ? 197 LYS A CG  1 
ATOM 507  C CD  . LYS A 1 197 ? 86.956  93.581  93.806  1.00 58.68  ? 197 LYS A CD  1 
ATOM 508  C CE  . LYS A 1 197 ? 86.510  95.016  93.595  1.00 65.44  ? 197 LYS A CE  1 
ATOM 509  N NZ  . LYS A 1 197 ? 87.639  95.892  93.177  1.00 67.30  ? 197 LYS A NZ  1 
ATOM 510  N N   . MET A 1 198 ? 84.706  88.057  93.814  1.00 48.50  ? 198 MET A N   1 
ATOM 511  C CA  . MET A 1 198 ? 84.964  86.635  93.637  1.00 45.99  ? 198 MET A CA  1 
ATOM 512  C C   . MET A 1 198 ? 85.426  86.397  92.207  1.00 47.85  ? 198 MET A C   1 
ATOM 513  O O   . MET A 1 198 ? 84.713  86.735  91.258  1.00 56.75  ? 198 MET A O   1 
ATOM 514  C CB  . MET A 1 198 ? 83.709  85.825  93.959  1.00 44.85  ? 198 MET A CB  1 
ATOM 515  C CG  . MET A 1 198 ? 83.892  84.325  93.915  1.00 52.60  ? 198 MET A CG  1 
ATOM 516  S SD  . MET A 1 198 ? 82.491  83.478  94.664  1.00 71.37  ? 198 MET A SD  1 
ATOM 517  C CE  . MET A 1 198 ? 81.141  84.169  93.713  1.00 63.05  ? 198 MET A CE  1 
ATOM 518  N N   . PHE A 1 199 ? 86.611  85.812  92.055  1.00 42.49  ? 199 PHE A N   1 
ATOM 519  C CA  . PHE A 1 199 ? 87.232  85.609  90.753  1.00 41.17  ? 199 PHE A CA  1 
ATOM 520  C C   . PHE A 1 199 ? 87.130  84.142  90.366  1.00 48.86  ? 199 PHE A C   1 
ATOM 521  O O   . PHE A 1 199 ? 87.607  83.269  91.097  1.00 62.17  ? 199 PHE A O   1 
ATOM 522  C CB  . PHE A 1 199 ? 88.694  86.050  90.772  1.00 42.47  ? 199 PHE A CB  1 
ATOM 523  C CG  . PHE A 1 199 ? 88.918  87.355  91.468  1.00 50.88  ? 199 PHE A CG  1 
ATOM 524  C CD1 . PHE A 1 199 ? 88.468  88.538  90.914  1.00 50.24  ? 199 PHE A CD1 1 
ATOM 525  C CD2 . PHE A 1 199 ? 89.588  87.399  92.676  1.00 45.94  ? 199 PHE A CD2 1 
ATOM 526  C CE1 . PHE A 1 199 ? 88.671  89.738  91.558  1.00 52.85  ? 199 PHE A CE1 1 
ATOM 527  C CE2 . PHE A 1 199 ? 89.796  88.594  93.320  1.00 48.30  ? 199 PHE A CE2 1 
ATOM 528  C CZ  . PHE A 1 199 ? 89.335  89.766  92.764  1.00 51.88  ? 199 PHE A CZ  1 
ATOM 529  N N   . ASP A 1 200 ? 86.534  83.879  89.210  1.00 53.29  ? 200 ASP A N   1 
ATOM 530  C CA  . ASP A 1 200 ? 86.423  82.534  88.665  1.00 43.90  ? 200 ASP A CA  1 
ATOM 531  C C   . ASP A 1 200 ? 87.420  82.372  87.528  1.00 53.52  ? 200 ASP A C   1 
ATOM 532  O O   . ASP A 1 200 ? 87.437  83.176  86.591  1.00 64.80  ? 200 ASP A O   1 
ATOM 533  C CB  . ASP A 1 200 ? 85.002  82.266  88.171  1.00 48.21  ? 200 ASP A CB  1 
ATOM 534  C CG  . ASP A 1 200 ? 84.788  80.824  87.767  1.00 64.16  ? 200 ASP A CG  1 
ATOM 535  O OD1 . ASP A 1 200 ? 85.690  79.993  87.997  1.00 63.53  ? 200 ASP A OD1 1 
ATOM 536  O OD2 . ASP A 1 200 ? 83.708  80.518  87.221  1.00 68.80  ? 200 ASP A OD2 1 
ATOM 537  N N   . VAL A 1 201 ? 88.250  81.337  87.614  1.00 51.74  ? 201 VAL A N   1 
ATOM 538  C CA  . VAL A 1 201 ? 89.279  81.096  86.611  1.00 53.21  ? 201 VAL A CA  1 
ATOM 539  C C   . VAL A 1 201 ? 89.061  79.729  85.979  1.00 58.34  ? 201 VAL A C   1 
ATOM 540  O O   . VAL A 1 201 ? 90.016  79.065  85.562  1.00 60.59  ? 201 VAL A O   1 
ATOM 541  C CB  . VAL A 1 201 ? 90.685  81.203  87.227  1.00 51.38  ? 201 VAL A CB  1 
ATOM 542  C CG1 . VAL A 1 201 ? 90.963  82.630  87.641  1.00 53.04  ? 201 VAL A CG1 1 
ATOM 543  C CG2 . VAL A 1 201 ? 90.812  80.274  88.417  1.00 48.08  ? 201 VAL A CG2 1 
ATOM 544  N N   . GLY A 1 202 ? 87.801  79.298  85.907  1.00 56.53  ? 202 GLY A N   1 
ATOM 545  C CA  . GLY A 1 202 ? 87.506  78.007  85.313  1.00 50.55  ? 202 GLY A CA  1 
ATOM 546  C C   . GLY A 1 202 ? 87.739  77.964  83.818  1.00 54.61  ? 202 GLY A C   1 
ATOM 547  O O   . GLY A 1 202 ? 88.001  76.894  83.260  1.00 55.29  ? 202 GLY A O   1 
ATOM 548  N N   . ALA A 1 203 ? 87.651  79.112  83.149  1.00 63.96  ? 203 ALA A N   1 
ATOM 549  C CA  . ALA A 1 203 ? 87.861  79.167  81.709  1.00 62.10  ? 203 ALA A CA  1 
ATOM 550  C C   . ALA A 1 203 ? 89.332  79.190  81.318  1.00 59.17  ? 203 ALA A C   1 
ATOM 551  O O   . ALA A 1 203 ? 89.646  78.956  80.147  1.00 59.87  ? 203 ALA A O   1 
ATOM 552  C CB  . ALA A 1 203 ? 87.158  80.394  81.124  1.00 59.22  ? 203 ALA A CB  1 
ATOM 553  N N   . GLN A 1 204 ? 90.234  79.460  82.257  1.00 55.71  ? 204 GLN A N   1 
ATOM 554  C CA  . GLN A 1 204 ? 91.665  79.498  81.965  1.00 58.17  ? 204 GLN A CA  1 
ATOM 555  C C   . GLN A 1 204 ? 92.178  78.070  81.845  1.00 61.49  ? 204 GLN A C   1 
ATOM 556  O O   . GLN A 1 204 ? 92.507  77.428  82.844  1.00 58.94  ? 204 GLN A O   1 
ATOM 557  C CB  . GLN A 1 204 ? 92.412  80.269  83.048  1.00 59.45  ? 204 GLN A CB  1 
ATOM 558  C CG  . GLN A 1 204 ? 92.316  81.782  82.925  1.00 56.39  ? 204 GLN A CG  1 
ATOM 559  C CD  . GLN A 1 204 ? 93.090  82.320  81.737  1.00 62.33  ? 204 GLN A CD  1 
ATOM 560  O OE1 . GLN A 1 204 ? 93.970  81.648  81.200  1.00 67.79  ? 204 GLN A OE1 1 
ATOM 561  N NE2 . GLN A 1 204 ? 92.765  83.535  81.320  1.00 55.66  ? 204 GLN A NE2 1 
ATOM 562  N N   . ARG A 1 205 ? 92.254  77.571  80.614  1.00 60.89  ? 205 ARG A N   1 
ATOM 563  C CA  . ARG A 1 205 ? 92.726  76.219  80.347  1.00 61.23  ? 205 ARG A CA  1 
ATOM 564  C C   . ARG A 1 205 ? 94.239  76.138  80.199  1.00 63.73  ? 205 ARG A C   1 
ATOM 565  O O   . ARG A 1 205 ? 94.769  75.044  79.984  1.00 60.16  ? 205 ARG A O   1 
ATOM 566  C CB  . ARG A 1 205 ? 92.056  75.669  79.084  1.00 56.44  ? 205 ARG A CB  1 
ATOM 567  N N   . SER A 1 206 ? 94.943  77.262  80.308  1.00 62.24  ? 206 SER A N   1 
ATOM 568  C CA  . SER A 1 206 ? 96.392  77.275  80.188  1.00 53.65  ? 206 SER A CA  1 
ATOM 569  C C   . SER A 1 206 ? 97.035  76.683  81.440  1.00 51.81  ? 206 SER A C   1 
ATOM 570  O O   . SER A 1 206 ? 96.362  76.209  82.359  1.00 57.18  ? 206 SER A O   1 
ATOM 571  C CB  . SER A 1 206 ? 96.882  78.697  79.941  1.00 54.61  ? 206 SER A CB  1 
ATOM 572  O OG  . SER A 1 206 ? 96.463  79.558  80.983  1.00 57.56  ? 206 SER A OG  1 
ATOM 573  N N   . GLU A 1 207 ? 98.365  76.706  81.473  1.00 58.74  ? 207 GLU A N   1 
ATOM 574  C CA  . GLU A 1 207 ? 99.090  76.172  82.618  1.00 62.54  ? 207 GLU A CA  1 
ATOM 575  C C   . GLU A 1 207 ? 98.828  77.029  83.848  1.00 63.30  ? 207 GLU A C   1 
ATOM 576  O O   . GLU A 1 207 ? 99.022  78.247  83.823  1.00 68.23  ? 207 GLU A O   1 
ATOM 577  C CB  . GLU A 1 207 ? 100.587 76.109  82.322  1.00 60.91  ? 207 GLU A CB  1 
ATOM 578  C CG  . GLU A 1 207 ? 100.946 75.218  81.148  1.00 67.98  ? 207 GLU A CG  1 
ATOM 579  C CD  . GLU A 1 207 ? 102.443 75.069  80.967  1.00 72.72  ? 207 GLU A CD  1 
ATOM 580  O OE1 . GLU A 1 207 ? 103.199 75.571  81.826  1.00 70.46  ? 207 GLU A OE1 1 
ATOM 581  O OE2 . GLU A 1 207 ? 102.864 74.450  79.966  1.00 67.83  ? 207 GLU A OE2 1 
ATOM 582  N N   . ARG A 1 208 ? 98.388  76.382  84.929  1.00 56.66  ? 208 ARG A N   1 
ATOM 583  C CA  . ARG A 1 208 ? 98.018  77.115  86.134  1.00 53.37  ? 208 ARG A CA  1 
ATOM 584  C C   . ARG A 1 208 ? 99.222  77.798  86.767  1.00 51.48  ? 208 ARG A C   1 
ATOM 585  O O   . ARG A 1 208 ? 99.116  78.933  87.242  1.00 49.16  ? 208 ARG A O   1 
ATOM 586  C CB  . ARG A 1 208 ? 97.350  76.173  87.131  1.00 53.03  ? 208 ARG A CB  1 
ATOM 587  C CG  . ARG A 1 208 ? 96.784  76.864  88.353  1.00 55.39  ? 208 ARG A CG  1 
ATOM 588  C CD  . ARG A 1 208 ? 96.136  75.862  89.287  1.00 56.21  ? 208 ARG A CD  1 
ATOM 589  N NE  . ARG A 1 208 ? 95.167  75.027  88.590  1.00 63.04  ? 208 ARG A NE  1 
ATOM 590  C CZ  . ARG A 1 208 ? 93.898  75.357  88.393  1.00 62.39  ? 208 ARG A CZ  1 
ATOM 591  N NH1 . ARG A 1 208 ? 93.407  76.505  88.828  1.00 61.92  ? 208 ARG A NH1 1 
ATOM 592  N NH2 . ARG A 1 208 ? 93.102  74.513  87.743  1.00 54.26  ? 208 ARG A NH2 1 
ATOM 593  N N   . LYS A 1 209 ? 100.375 77.126  86.780  1.00 51.38  ? 209 LYS A N   1 
ATOM 594  C CA  . LYS A 1 209 ? 101.535 77.652  87.491  1.00 53.74  ? 209 LYS A CA  1 
ATOM 595  C C   . LYS A 1 209 ? 102.035 78.965  86.908  1.00 56.98  ? 209 LYS A C   1 
ATOM 596  O O   . LYS A 1 209 ? 102.776 79.685  87.584  1.00 56.76  ? 209 LYS A O   1 
ATOM 597  C CB  . LYS A 1 209 ? 102.665 76.624  87.491  1.00 49.97  ? 209 LYS A CB  1 
ATOM 598  C CG  . LYS A 1 209 ? 103.226 76.324  86.120  1.00 52.32  ? 209 LYS A CG  1 
ATOM 599  C CD  . LYS A 1 209 ? 104.435 75.415  86.213  1.00 55.14  ? 209 LYS A CD  1 
ATOM 600  C CE  . LYS A 1 209 ? 105.030 75.149  84.842  1.00 60.79  ? 209 LYS A CE  1 
ATOM 601  N NZ  . LYS A 1 209 ? 106.241 74.287  84.921  1.00 58.30  ? 209 LYS A NZ  1 
ATOM 602  N N   . LYS A 1 210 ? 101.654 79.292  85.673  1.00 54.89  ? 210 LYS A N   1 
ATOM 603  C CA  . LYS A 1 210 ? 102.135 80.520  85.055  1.00 48.66  ? 210 LYS A CA  1 
ATOM 604  C C   . LYS A 1 210 ? 101.392 81.746  85.562  1.00 47.69  ? 210 LYS A C   1 
ATOM 605  O O   . LYS A 1 210 ? 101.977 82.831  85.633  1.00 56.13  ? 210 LYS A O   1 
ATOM 606  C CB  . LYS A 1 210 ? 102.026 80.425  83.534  1.00 48.96  ? 210 LYS A CB  1 
ATOM 607  C CG  . LYS A 1 210 ? 102.747 79.227  82.945  1.00 52.68  ? 210 LYS A CG  1 
ATOM 608  C CD  . LYS A 1 210 ? 104.195 79.179  83.398  1.00 45.91  ? 210 LYS A CD  1 
ATOM 609  C CE  . LYS A 1 210 ? 104.980 80.366  82.886  1.00 50.67  ? 210 LYS A CE  1 
ATOM 610  N NZ  . LYS A 1 210 ? 106.387 80.333  83.358  1.00 54.11  ? 210 LYS A NZ  1 
ATOM 611  N N   . TRP A 1 211 ? 100.114 81.603  85.911  1.00 53.04  ? 211 TRP A N   1 
ATOM 612  C CA  . TRP A 1 211 ? 99.299  82.733  86.331  1.00 47.50  ? 211 TRP A CA  1 
ATOM 613  C C   . TRP A 1 211 ? 98.676  82.561  87.709  1.00 46.92  ? 211 TRP A C   1 
ATOM 614  O O   . TRP A 1 211 ? 97.906  83.431  88.127  1.00 54.00  ? 211 TRP A O   1 
ATOM 615  C CB  . TRP A 1 211 ? 98.187  83.001  85.309  1.00 41.78  ? 211 TRP A CB  1 
ATOM 616  C CG  . TRP A 1 211 ? 97.375  81.793  84.972  1.00 46.73  ? 211 TRP A CG  1 
ATOM 617  C CD1 . TRP A 1 211 ? 97.531  80.982  83.892  1.00 45.14  ? 211 TRP A CD1 1 
ATOM 618  C CD2 . TRP A 1 211 ? 96.292  81.244  85.732  1.00 54.03  ? 211 TRP A CD2 1 
ATOM 619  N NE1 . TRP A 1 211 ? 96.607  79.968  83.922  1.00 49.44  ? 211 TRP A NE1 1 
ATOM 620  C CE2 . TRP A 1 211 ? 95.836  80.106  85.044  1.00 51.34  ? 211 TRP A CE2 1 
ATOM 621  C CE3 . TRP A 1 211 ? 95.661  81.607  86.924  1.00 44.97  ? 211 TRP A CE3 1 
ATOM 622  C CZ2 . TRP A 1 211 ? 94.782  79.328  85.508  1.00 54.33  ? 211 TRP A CZ2 1 
ATOM 623  C CZ3 . TRP A 1 211 ? 94.618  80.835  87.383  1.00 48.88  ? 211 TRP A CZ3 1 
ATOM 624  C CH2 . TRP A 1 211 ? 94.187  79.709  86.677  1.00 54.82  ? 211 TRP A CH2 1 
ATOM 625  N N   . ILE A 1 212 ? 98.975  81.475  88.425  1.00 39.72  ? 212 ILE A N   1 
ATOM 626  C CA  . ILE A 1 212 ? 98.368  81.278  89.738  1.00 42.90  ? 212 ILE A CA  1 
ATOM 627  C C   . ILE A 1 212 ? 98.937  82.264  90.748  1.00 43.60  ? 212 ILE A C   1 
ATOM 628  O O   . ILE A 1 212 ? 98.278  82.596  91.739  1.00 47.77  ? 212 ILE A O   1 
ATOM 629  C CB  . ILE A 1 212 ? 98.539  79.820  90.208  1.00 42.85  ? 212 ILE A CB  1 
ATOM 630  C CG1 . ILE A 1 212 ? 97.600  79.518  91.375  1.00 41.94  ? 212 ILE A CG1 1 
ATOM 631  C CG2 . ILE A 1 212 ? 99.970  79.548  90.619  1.00 48.53  ? 212 ILE A CG2 1 
ATOM 632  C CD1 . ILE A 1 212 ? 96.134  79.679  91.036  1.00 43.56  ? 212 ILE A CD1 1 
ATOM 633  N N   . HIS A 1 213 ? 100.155 82.756  90.517  1.00 47.05  ? 213 HIS A N   1 
ATOM 634  C CA  . HIS A 1 213 ? 100.767 83.712  91.429  1.00 40.69  ? 213 HIS A CA  1 
ATOM 635  C C   . HIS A 1 213 ? 100.106 85.079  91.378  1.00 34.87  ? 213 HIS A C   1 
ATOM 636  O O   . HIS A 1 213 ? 100.346 85.894  92.273  1.00 45.07  ? 213 HIS A O   1 
ATOM 637  C CB  . HIS A 1 213 ? 102.260 83.843  91.132  1.00 47.07  ? 213 HIS A CB  1 
ATOM 638  C CG  . HIS A 1 213 ? 102.574 84.054  89.685  1.00 46.82  ? 213 HIS A CG  1 
ATOM 639  N ND1 . HIS A 1 213 ? 102.194 85.185  88.997  1.00 45.56  ? 213 HIS A ND1 1 
ATOM 640  C CD2 . HIS A 1 213 ? 103.235 83.277  88.796  1.00 43.75  ? 213 HIS A CD2 1 
ATOM 641  C CE1 . HIS A 1 213 ? 102.605 85.095  87.745  1.00 43.47  ? 213 HIS A CE1 1 
ATOM 642  N NE2 . HIS A 1 213 ? 103.240 83.947  87.597  1.00 53.91  ? 213 HIS A NE2 1 
ATOM 643  N N   . CYS A 1 214 ? 99.291  85.351  90.359  1.00 38.08  ? 214 CYS A N   1 
ATOM 644  C CA  . CYS A 1 214 ? 98.578  86.619  90.295  1.00 41.20  ? 214 CYS A CA  1 
ATOM 645  C C   . CYS A 1 214 ? 97.592  86.775  91.441  1.00 42.70  ? 214 CYS A C   1 
ATOM 646  O O   . CYS A 1 214 ? 97.245  87.905  91.798  1.00 50.08  ? 214 CYS A O   1 
ATOM 647  C CB  . CYS A 1 214 ? 97.841  86.742  88.961  1.00 39.93  ? 214 CYS A CB  1 
ATOM 648  S SG  . CYS A 1 214 ? 98.905  86.668  87.507  1.00 57.57  ? 214 CYS A SG  1 
ATOM 649  N N   . PHE A 1 215 ? 97.136  85.671  92.025  1.00 41.69  ? 215 PHE A N   1 
ATOM 650  C CA  . PHE A 1 215 ? 96.146  85.697  93.089  1.00 42.22  ? 215 PHE A CA  1 
ATOM 651  C C   . PHE A 1 215 ? 96.764  85.594  94.473  1.00 46.07  ? 215 PHE A C   1 
ATOM 652  O O   . PHE A 1 215 ? 96.028  85.490  95.459  1.00 51.00  ? 215 PHE A O   1 
ATOM 653  C CB  . PHE A 1 215 ? 95.129  84.577  92.881  1.00 45.56  ? 215 PHE A CB  1 
ATOM 654  C CG  . PHE A 1 215 ? 94.341  84.717  91.618  1.00 45.91  ? 215 PHE A CG  1 
ATOM 655  C CD1 . PHE A 1 215 ? 93.178  85.465  91.595  1.00 39.10  ? 215 PHE A CD1 1 
ATOM 656  C CD2 . PHE A 1 215 ? 94.773  84.118  90.450  1.00 41.99  ? 215 PHE A CD2 1 
ATOM 657  C CE1 . PHE A 1 215 ? 92.459  85.601  90.434  1.00 41.28  ? 215 PHE A CE1 1 
ATOM 658  C CE2 . PHE A 1 215 ? 94.057  84.254  89.288  1.00 40.40  ? 215 PHE A CE2 1 
ATOM 659  C CZ  . PHE A 1 215 ? 92.899  84.997  89.279  1.00 40.45  ? 215 PHE A CZ  1 
ATOM 660  N N   . GLU A 1 216 ? 98.089  85.615  94.575  1.00 51.43  ? 216 GLU A N   1 
ATOM 661  C CA  . GLU A 1 216 ? 98.728  85.654  95.881  1.00 47.16  ? 216 GLU A CA  1 
ATOM 662  C C   . GLU A 1 216 ? 98.315  86.921  96.610  1.00 52.98  ? 216 GLU A C   1 
ATOM 663  O O   . GLU A 1 216 ? 98.598  88.032  96.153  1.00 58.55  ? 216 GLU A O   1 
ATOM 664  C CB  . GLU A 1 216 ? 100.244 85.600  95.740  1.00 43.09  ? 216 GLU A CB  1 
ATOM 665  C CG  . GLU A 1 216 ? 100.961 85.665  97.072  1.00 47.38  ? 216 GLU A CG  1 
ATOM 666  C CD  . GLU A 1 216 ? 102.451 85.867  96.930  1.00 56.50  ? 216 GLU A CD  1 
ATOM 667  O OE1 . GLU A 1 216 ? 102.886 86.364  95.871  1.00 64.87  ? 216 GLU A OE1 1 
ATOM 668  O OE2 . GLU A 1 216 ? 103.188 85.531  97.879  1.00 52.54  ? 216 GLU A OE2 1 
ATOM 669  N N   . GLY A 1 217 ? 97.640  86.757  97.743  1.00 47.13  ? 217 GLY A N   1 
ATOM 670  C CA  . GLY A 1 217 ? 97.139  87.883  98.500  1.00 41.54  ? 217 GLY A CA  1 
ATOM 671  C C   . GLY A 1 217 ? 95.635  87.975  98.581  1.00 39.53  ? 217 GLY A C   1 
ATOM 672  O O   . GLY A 1 217 ? 95.126  88.911  99.206  1.00 50.52  ? 217 GLY A O   1 
ATOM 673  N N   . VAL A 1 218 ? 94.901  87.049  97.964  1.00 39.04  ? 218 VAL A N   1 
ATOM 674  C CA  . VAL A 1 218 ? 93.452  87.048  98.096  1.00 38.75  ? 218 VAL A CA  1 
ATOM 675  C C   . VAL A 1 218 ? 93.082  86.735  99.539  1.00 41.53  ? 218 VAL A C   1 
ATOM 676  O O   . VAL A 1 218 ? 93.828  86.070  100.269 1.00 47.43  ? 218 VAL A O   1 
ATOM 677  C CB  . VAL A 1 218 ? 92.813  86.041  97.125  1.00 35.02  ? 218 VAL A CB  1 
ATOM 678  C CG1 . VAL A 1 218 ? 93.005  86.497  95.692  1.00 42.16  ? 218 VAL A CG1 1 
ATOM 679  C CG2 . VAL A 1 218 ? 93.405  84.659  97.332  1.00 35.36  ? 218 VAL A CG2 1 
ATOM 680  N N   . THR A 1 219 ? 91.923  87.235  99.965  1.00 35.79  ? 219 THR A N   1 
ATOM 681  C CA  . THR A 1 219 ? 91.498  87.035  101.345 1.00 34.39  ? 219 THR A CA  1 
ATOM 682  C C   . THR A 1 219 ? 91.294  85.557  101.651 1.00 41.94  ? 219 THR A C   1 
ATOM 683  O O   . THR A 1 219 ? 91.776  85.049  102.669 1.00 54.27  ? 219 THR A O   1 
ATOM 684  C CB  . THR A 1 219 ? 90.222  87.829  101.615 1.00 38.02  ? 219 THR A CB  1 
ATOM 685  O OG1 . THR A 1 219 ? 90.464  89.214  101.347 1.00 43.11  ? 219 THR A OG1 1 
ATOM 686  C CG2 . THR A 1 219 ? 89.789  87.674  103.060 1.00 43.35  ? 219 THR A CG2 1 
ATOM 687  N N   . ALA A 1 220 ? 90.603  84.843  100.767 1.00 38.75  ? 220 ALA A N   1 
ATOM 688  C CA  . ALA A 1 220 ? 90.335  83.431  100.980 1.00 37.41  ? 220 ALA A CA  1 
ATOM 689  C C   . ALA A 1 220 ? 90.136  82.749  99.636  1.00 45.38  ? 220 ALA A C   1 
ATOM 690  O O   . ALA A 1 220 ? 89.882  83.396  98.619  1.00 55.79  ? 220 ALA A O   1 
ATOM 691  C CB  . ALA A 1 220 ? 89.111  83.218  101.876 1.00 40.56  ? 220 ALA A CB  1 
ATOM 692  N N   . ILE A 1 221 ? 90.263  81.427  99.647  1.00 43.93  ? 221 ILE A N   1 
ATOM 693  C CA  . ILE A 1 221 ? 90.046  80.593  98.472  1.00 38.45  ? 221 ILE A CA  1 
ATOM 694  C C   . ILE A 1 221 ? 88.812  79.744  98.727  1.00 46.13  ? 221 ILE A C   1 
ATOM 695  O O   . ILE A 1 221 ? 88.744  79.024  99.730  1.00 55.79  ? 221 ILE A O   1 
ATOM 696  C CB  . ILE A 1 221 ? 91.262  79.705  98.173  1.00 36.65  ? 221 ILE A CB  1 
ATOM 697  C CG1 . ILE A 1 221 ? 92.486  80.556  97.844  1.00 40.00  ? 221 ILE A CG1 1 
ATOM 698  C CG2 . ILE A 1 221 ? 90.951  78.746  97.043  1.00 42.67  ? 221 ILE A CG2 1 
ATOM 699  C CD1 . ILE A 1 221 ? 93.721  79.747  97.548  1.00 40.40  ? 221 ILE A CD1 1 
ATOM 700  N N   . ILE A 1 222 ? 87.835  79.829  97.833  1.00 40.71  ? 222 ILE A N   1 
ATOM 701  C CA  . ILE A 1 222 ? 86.624  79.023  97.919  1.00 45.05  ? 222 ILE A CA  1 
ATOM 702  C C   . ILE A 1 222 ? 86.811  77.828  96.998  1.00 42.79  ? 222 ILE A C   1 
ATOM 703  O O   . ILE A 1 222 ? 86.741  77.960  95.773  1.00 60.23  ? 222 ILE A O   1 
ATOM 704  C CB  . ILE A 1 222 ? 85.371  79.825  97.548  1.00 48.37  ? 222 ILE A CB  1 
ATOM 705  C CG1 . ILE A 1 222 ? 85.197  81.011  98.494  1.00 48.51  ? 222 ILE A CG1 1 
ATOM 706  C CG2 . ILE A 1 222 ? 84.142  78.936  97.590  1.00 45.70  ? 222 ILE A CG2 1 
ATOM 707  C CD1 . ILE A 1 222 ? 83.891  81.739  98.316  1.00 49.87  ? 222 ILE A CD1 1 
ATOM 708  N N   . PHE A 1 223 ? 87.045  76.659  97.581  1.00 49.72  ? 223 PHE A N   1 
ATOM 709  C CA  . PHE A 1 223 ? 87.258  75.429  96.833  1.00 52.18  ? 223 PHE A CA  1 
ATOM 710  C C   . PHE A 1 223 ? 86.000  74.580  96.938  1.00 55.57  ? 223 PHE A C   1 
ATOM 711  O O   . PHE A 1 223 ? 85.570  74.239  98.044  1.00 65.67  ? 223 PHE A O   1 
ATOM 712  C CB  . PHE A 1 223 ? 88.470  74.670  97.370  1.00 54.45  ? 223 PHE A CB  1 
ATOM 713  C CG  . PHE A 1 223 ? 89.011  73.643  96.423  1.00 59.43  ? 223 PHE A CG  1 
ATOM 714  C CD1 . PHE A 1 223 ? 88.482  72.368  96.387  1.00 66.54  ? 223 PHE A CD1 1 
ATOM 715  C CD2 . PHE A 1 223 ? 90.062  73.948  95.580  1.00 57.80  ? 223 PHE A CD2 1 
ATOM 716  C CE1 . PHE A 1 223 ? 88.980  71.421  95.519  1.00 59.41  ? 223 PHE A CE1 1 
ATOM 717  C CE2 . PHE A 1 223 ? 90.565  73.004  94.711  1.00 60.45  ? 223 PHE A CE2 1 
ATOM 718  C CZ  . PHE A 1 223 ? 90.023  71.739  94.682  1.00 62.17  ? 223 PHE A CZ  1 
ATOM 719  N N   . CYS A 1 224 ? 85.416  74.241  95.794  1.00 65.83  ? 224 CYS A N   1 
ATOM 720  C CA  . CYS A 1 224 ? 84.170  73.489  95.745  1.00 71.34  ? 224 CYS A CA  1 
ATOM 721  C C   . CYS A 1 224 ? 84.452  72.041  95.373  1.00 78.60  ? 224 CYS A C   1 
ATOM 722  O O   . CYS A 1 224 ? 85.133  71.769  94.380  1.00 84.58  ? 224 CYS A O   1 
ATOM 723  C CB  . CYS A 1 224 ? 83.193  74.112  94.750  1.00 74.06  ? 224 CYS A CB  1 
ATOM 724  S SG  . CYS A 1 224 ? 82.656  75.782  95.180  1.00 83.66  ? 224 CYS A SG  1 
ATOM 725  N N   . VAL A 1 225 ? 83.928  71.118  96.174  1.00 84.31  ? 225 VAL A N   1 
ATOM 726  C CA  . VAL A 1 225 ? 84.076  69.686  95.952  1.00 80.92  ? 225 VAL A CA  1 
ATOM 727  C C   . VAL A 1 225 ? 82.687  69.071  95.900  1.00 83.11  ? 225 VAL A C   1 
ATOM 728  O O   . VAL A 1 225 ? 81.838  69.372  96.746  1.00 84.97  ? 225 VAL A O   1 
ATOM 729  C CB  . VAL A 1 225 ? 84.922  69.023  97.053  1.00 80.78  ? 225 VAL A CB  1 
ATOM 730  C CG1 . VAL A 1 225 ? 85.055  67.535  96.794  1.00 84.65  ? 225 VAL A CG1 1 
ATOM 731  C CG2 . VAL A 1 225 ? 86.286  69.677  97.139  1.00 81.81  ? 225 VAL A CG2 1 
ATOM 732  N N   . ALA A 1 226 ? 82.455  68.221  94.906  1.00 97.48  ? 226 ALA A N   1 
ATOM 733  C CA  . ALA A 1 226 ? 81.182  67.525  94.761  1.00 97.27  ? 226 ALA A CA  1 
ATOM 734  C C   . ALA A 1 226 ? 81.246  66.226  95.553  1.00 99.80  ? 226 ALA A C   1 
ATOM 735  O O   . ALA A 1 226 ? 82.035  65.332  95.229  1.00 98.73  ? 226 ALA A O   1 
ATOM 736  C CB  . ALA A 1 226 ? 80.876  67.259  93.291  1.00 98.07  ? 226 ALA A CB  1 
ATOM 737  N N   . LEU A 1 227 ? 80.423  66.126  96.599  1.00 106.24 ? 227 LEU A N   1 
ATOM 738  C CA  . LEU A 1 227 ? 80.408  64.917  97.416  1.00 103.54 ? 227 LEU A CA  1 
ATOM 739  C C   . LEU A 1 227 ? 79.913  63.720  96.617  1.00 108.59 ? 227 LEU A C   1 
ATOM 740  O O   . LEU A 1 227 ? 80.425  62.606  96.777  1.00 111.07 ? 227 LEU A O   1 
ATOM 741  C CB  . LEU A 1 227 ? 79.542  65.125  98.657  1.00 103.53 ? 227 LEU A CB  1 
ATOM 742  C CG  . LEU A 1 227 ? 80.090  66.049  99.742  1.00 102.69 ? 227 LEU A CG  1 
ATOM 743  C CD1 . LEU A 1 227 ? 79.071  66.228  100.851 1.00 102.63 ? 227 LEU A CD1 1 
ATOM 744  C CD2 . LEU A 1 227 ? 81.385  65.489  100.296 1.00 104.72 ? 227 LEU A CD2 1 
ATOM 745  N N   . SER A 1 228 ? 78.917  63.929  95.754  1.00 118.94 ? 228 SER A N   1 
ATOM 746  C CA  . SER A 1 228 ? 78.360  62.832  94.973  1.00 118.00 ? 228 SER A CA  1 
ATOM 747  C C   . SER A 1 228 ? 79.361  62.253  93.985  1.00 117.24 ? 228 SER A C   1 
ATOM 748  O O   . SER A 1 228 ? 79.178  61.119  93.531  1.00 119.70 ? 228 SER A O   1 
ATOM 749  C CB  . SER A 1 228 ? 77.116  63.299  94.221  1.00 118.77 ? 228 SER A CB  1 
ATOM 750  O OG  . SER A 1 228 ? 77.457  64.236  93.217  1.00 119.06 ? 228 SER A OG  1 
ATOM 751  N N   . ASP A 1 229 ? 80.409  62.995  93.643  1.00 120.12 ? 229 ASP A N   1 
ATOM 752  C CA  . ASP A 1 229 ? 81.409  62.519  92.689  1.00 122.28 ? 229 ASP A CA  1 
ATOM 753  C C   . ASP A 1 229 ? 82.490  61.695  93.378  1.00 122.26 ? 229 ASP A C   1 
ATOM 754  O O   . ASP A 1 229 ? 83.682  61.961  93.242  1.00 122.72 ? 229 ASP A O   1 
ATOM 755  C CB  . ASP A 1 229 ? 82.016  63.700  91.942  1.00 121.27 ? 229 ASP A CB  1 
ATOM 756  C CG  . ASP A 1 229 ? 80.983  64.485  91.158  1.00 122.45 ? 229 ASP A CG  1 
ATOM 757  O OD1 . ASP A 1 229 ? 79.781  64.166  91.271  1.00 122.84 ? 229 ASP A OD1 1 
ATOM 758  O OD2 . ASP A 1 229 ? 81.373  65.420  90.427  1.00 121.73 ? 229 ASP A OD2 1 
ATOM 759  N N   . TYR A 1 230 ? 82.076  60.677  94.129  1.00 128.66 ? 230 TYR A N   1 
ATOM 760  C CA  . TYR A 1 230 ? 83.005  59.754  94.769  1.00 128.31 ? 230 TYR A CA  1 
ATOM 761  C C   . TYR A 1 230 ? 83.053  58.396  94.094  1.00 130.43 ? 230 TYR A C   1 
ATOM 762  O O   . TYR A 1 230 ? 84.128  57.802  93.993  1.00 131.22 ? 230 TYR A O   1 
ATOM 763  C CB  . TYR A 1 230 ? 82.650  59.575  96.251  1.00 129.18 ? 230 TYR A CB  1 
ATOM 764  C CG  . TYR A 1 230 ? 81.347  58.852  96.514  1.00 130.79 ? 230 TYR A CG  1 
ATOM 765  C CD1 . TYR A 1 230 ? 80.133  59.519  96.442  1.00 130.14 ? 230 TYR A CD1 1 
ATOM 766  C CD2 . TYR A 1 230 ? 81.334  57.505  96.850  1.00 131.54 ? 230 TYR A CD2 1 
ATOM 767  C CE1 . TYR A 1 230 ? 78.942  58.864  96.687  1.00 131.13 ? 230 TYR A CE1 1 
ATOM 768  C CE2 . TYR A 1 230 ? 80.149  56.842  97.096  1.00 130.87 ? 230 TYR A CE2 1 
ATOM 769  C CZ  . TYR A 1 230 ? 78.956  57.526  97.014  1.00 130.72 ? 230 TYR A CZ  1 
ATOM 770  O OH  . TYR A 1 230 ? 77.771  56.872  97.259  1.00 129.89 ? 230 TYR A OH  1 
ATOM 771  N N   . ASP A 1 231 ? 81.914  57.886  93.631  1.00 138.07 ? 231 ASP A N   1 
ATOM 772  C CA  . ASP A 1 231 ? 81.878  56.637  92.886  1.00 138.85 ? 231 ASP A CA  1 
ATOM 773  C C   . ASP A 1 231 ? 82.003  56.846  91.384  1.00 138.30 ? 231 ASP A C   1 
ATOM 774  O O   . ASP A 1 231 ? 82.110  55.863  90.644  1.00 137.85 ? 231 ASP A O   1 
ATOM 775  C CB  . ASP A 1 231 ? 80.582  55.878  93.187  1.00 138.45 ? 231 ASP A CB  1 
ATOM 776  C CG  . ASP A 1 231 ? 79.349  56.643  92.759  1.00 139.32 ? 231 ASP A CG  1 
ATOM 777  O OD1 . ASP A 1 231 ? 79.388  57.891  92.774  1.00 138.76 ? 231 ASP A OD1 1 
ATOM 778  O OD2 . ASP A 1 231 ? 78.340  55.997  92.408  1.00 139.31 ? 231 ASP A OD2 1 
ATOM 779  N N   . LEU A 1 232 ? 81.993  58.092  90.921  1.00 133.94 ? 232 LEU A N   1 
ATOM 780  C CA  . LEU A 1 232 ? 82.107  58.386  89.504  1.00 133.68 ? 232 LEU A CA  1 
ATOM 781  C C   . LEU A 1 232 ? 83.574  58.389  89.081  1.00 133.90 ? 232 LEU A C   1 
ATOM 782  O O   . LEU A 1 232 ? 84.490  58.398  89.906  1.00 133.29 ? 232 LEU A O   1 
ATOM 783  C CB  . LEU A 1 232 ? 81.453  59.728  89.182  1.00 133.71 ? 232 LEU A CB  1 
ATOM 784  C CG  . LEU A 1 232 ? 79.995  59.897  89.616  1.00 133.07 ? 232 LEU A CG  1 
ATOM 785  C CD1 . LEU A 1 232 ? 79.483  61.278  89.243  1.00 132.07 ? 232 LEU A CD1 1 
ATOM 786  C CD2 . LEU A 1 232 ? 79.121  58.816  89.003  1.00 133.28 ? 232 LEU A CD2 1 
ATOM 787  N N   . VAL A 1 233 ? 83.792  58.383  87.766  1.00 140.96 ? 233 VAL A N   1 
ATOM 788  C CA  . VAL A 1 233 ? 85.132  58.397  87.198  1.00 140.90 ? 233 VAL A CA  1 
ATOM 789  C C   . VAL A 1 233 ? 85.225  59.532  86.188  1.00 139.95 ? 233 VAL A C   1 
ATOM 790  O O   . VAL A 1 233 ? 84.218  60.025  85.675  1.00 139.00 ? 233 VAL A O   1 
ATOM 791  C CB  . VAL A 1 233 ? 85.503  57.055  86.533  1.00 140.77 ? 233 VAL A CB  1 
ATOM 792  C CG1 . VAL A 1 233 ? 85.549  55.943  87.569  1.00 139.64 ? 233 VAL A CG1 1 
ATOM 793  C CG2 . VAL A 1 233 ? 84.516  56.721  85.426  1.00 139.49 ? 233 VAL A CG2 1 
ATOM 794  N N   . LEU A 1 234 ? 86.458  59.949  85.913  1.00 139.70 ? 234 LEU A N   1 
ATOM 795  C CA  . LEU A 1 234 ? 86.689  61.016  84.950  1.00 140.63 ? 234 LEU A CA  1 
ATOM 796  C C   . LEU A 1 234 ? 86.284  60.569  83.551  1.00 140.16 ? 234 LEU A C   1 
ATOM 797  O O   . LEU A 1 234 ? 86.509  59.421  83.158  1.00 139.57 ? 234 LEU A O   1 
ATOM 798  C CB  . LEU A 1 234 ? 88.157  61.439  84.963  1.00 140.91 ? 234 LEU A CB  1 
ATOM 799  C CG  . LEU A 1 234 ? 88.660  62.155  86.217  1.00 140.33 ? 234 LEU A CG  1 
ATOM 800  C CD1 . LEU A 1 234 ? 90.157  62.398  86.129  1.00 138.61 ? 234 LEU A CD1 1 
ATOM 801  C CD2 . LEU A 1 234 ? 87.919  63.467  86.411  1.00 137.63 ? 234 LEU A CD2 1 
ATOM 802  N N   . ALA A 1 235 ? 85.674  61.488  82.800  1.00 138.27 ? 235 ALA A N   1 
ATOM 803  C CA  . ALA A 1 235 ? 85.258  61.170  81.439  1.00 138.66 ? 235 ALA A CA  1 
ATOM 804  C C   . ALA A 1 235 ? 86.457  60.904  80.539  1.00 139.52 ? 235 ALA A C   1 
ATOM 805  O O   . ALA A 1 235 ? 86.431  59.979  79.718  1.00 137.93 ? 235 ALA A O   1 
ATOM 806  C CB  . ALA A 1 235 ? 84.402  62.303  80.874  1.00 136.88 ? 235 ALA A CB  1 
ATOM 807  N N   . GLU A 1 236 ? 87.518  61.701  80.677  1.00 143.01 ? 236 GLU A N   1 
ATOM 808  C CA  . GLU A 1 236 ? 88.684  61.546  79.814  1.00 141.76 ? 236 GLU A CA  1 
ATOM 809  C C   . GLU A 1 236 ? 89.626  60.465  80.330  1.00 142.91 ? 236 GLU A C   1 
ATOM 810  O O   . GLU A 1 236 ? 90.010  59.559  79.582  1.00 142.85 ? 236 GLU A O   1 
ATOM 811  C CB  . GLU A 1 236 ? 89.420  62.881  79.687  1.00 140.43 ? 236 GLU A CB  1 
ATOM 812  N N   . ASP A 1 237 ? 90.016  60.549  81.605  1.00 145.85 ? 237 ASP A N   1 
ATOM 813  C CA  . ASP A 1 237 ? 90.960  59.581  82.156  1.00 145.72 ? 237 ASP A CA  1 
ATOM 814  C C   . ASP A 1 237 ? 90.370  58.176  82.182  1.00 146.56 ? 237 ASP A C   1 
ATOM 815  O O   . ASP A 1 237 ? 91.061  57.200  81.866  1.00 146.75 ? 237 ASP A O   1 
ATOM 816  C CB  . ASP A 1 237 ? 91.389  60.007  83.559  1.00 144.35 ? 237 ASP A CB  1 
ATOM 817  N N   . GLU A 1 238 ? 89.102  58.052  82.577  1.00 147.95 ? 238 GLU A N   1 
ATOM 818  C CA  . GLU A 1 238 ? 88.376  56.788  82.669  1.00 147.29 ? 238 GLU A CA  1 
ATOM 819  C C   . GLU A 1 238 ? 88.979  55.827  83.688  1.00 147.66 ? 238 GLU A C   1 
ATOM 820  O O   . GLU A 1 238 ? 88.519  54.684  83.801  1.00 146.78 ? 238 GLU A O   1 
ATOM 821  C CB  . GLU A 1 238 ? 88.267  56.096  81.303  1.00 145.32 ? 238 GLU A CB  1 
ATOM 822  N N   . GLU A 1 239 ? 89.997  56.256  84.435  1.00 144.38 ? 239 GLU A N   1 
ATOM 823  C CA  . GLU A 1 239 ? 90.613  55.422  85.457  1.00 143.52 ? 239 GLU A CA  1 
ATOM 824  C C   . GLU A 1 239 ? 90.863  56.142  86.773  1.00 144.43 ? 239 GLU A C   1 
ATOM 825  O O   . GLU A 1 239 ? 91.148  55.471  87.772  1.00 143.53 ? 239 GLU A O   1 
ATOM 826  C CB  . GLU A 1 239 ? 91.945  54.845  84.949  1.00 142.54 ? 239 GLU A CB  1 
ATOM 827  N N   . MET A 1 240 ? 90.768  57.467  86.812  1.00 135.61 ? 240 MET A N   1 
ATOM 828  C CA  . MET A 1 240 ? 90.989  58.237  88.029  1.00 134.33 ? 240 MET A CA  1 
ATOM 829  C C   . MET A 1 240 ? 89.648  58.595  88.655  1.00 134.88 ? 240 MET A C   1 
ATOM 830  O O   . MET A 1 240 ? 88.742  59.072  87.964  1.00 134.34 ? 240 MET A O   1 
ATOM 831  C CB  . MET A 1 240 ? 91.790  59.505  87.733  1.00 133.04 ? 240 MET A CB  1 
ATOM 832  C CG  . MET A 1 240 ? 92.095  60.347  88.959  1.00 134.49 ? 240 MET A CG  1 
ATOM 833  S SD  . MET A 1 240 ? 93.107  59.470  90.166  1.00 137.70 ? 240 MET A SD  1 
ATOM 834  C CE  . MET A 1 240 ? 94.572  59.129  89.194  1.00 132.15 ? 240 MET A CE  1 
ATOM 835  N N   . ASN A 1 241 ? 89.527  58.355  89.958  1.00 124.59 ? 241 ASN A N   1 
ATOM 836  C CA  . ASN A 1 241 ? 88.287  58.643  90.664  1.00 122.97 ? 241 ASN A CA  1 
ATOM 837  C C   . ASN A 1 241 ? 88.025  60.144  90.687  1.00 124.65 ? 241 ASN A C   1 
ATOM 838  O O   . ASN A 1 241 ? 88.951  60.950  90.815  1.00 124.57 ? 241 ASN A O   1 
ATOM 839  C CB  . ASN A 1 241 ? 88.353  58.091  92.086  1.00 120.31 ? 241 ASN A CB  1 
ATOM 840  C CG  . ASN A 1 241 ? 87.014  58.121  92.783  1.00 123.25 ? 241 ASN A CG  1 
ATOM 841  O OD1 . ASN A 1 241 ? 86.642  59.118  93.397  1.00 126.35 ? 241 ASN A OD1 1 
ATOM 842  N ND2 . ASN A 1 241 ? 86.278  57.021  92.694  1.00 124.05 ? 241 ASN A ND2 1 
ATOM 843  N N   . ARG A 1 242 ? 86.749  60.518  90.554  1.00 122.29 ? 242 ARG A N   1 
ATOM 844  C CA  . ARG A 1 242 ? 86.385  61.932  90.550  1.00 121.31 ? 242 ARG A CA  1 
ATOM 845  C C   . ARG A 1 242 ? 86.725  62.601  91.876  1.00 121.26 ? 242 ARG A C   1 
ATOM 846  O O   . ARG A 1 242 ? 87.217  63.734  91.899  1.00 119.99 ? 242 ARG A O   1 
ATOM 847  C CB  . ARG A 1 242 ? 84.898  62.090  90.236  1.00 119.76 ? 242 ARG A CB  1 
ATOM 848  C CG  . ARG A 1 242 ? 84.514  61.668  88.831  1.00 122.34 ? 242 ARG A CG  1 
ATOM 849  C CD  . ARG A 1 242 ? 84.656  62.812  87.845  1.00 123.14 ? 242 ARG A CD  1 
ATOM 850  N NE  . ARG A 1 242 ? 83.603  63.805  88.014  1.00 123.53 ? 242 ARG A NE  1 
ATOM 851  C CZ  . ARG A 1 242 ? 82.439  63.776  87.378  1.00 123.49 ? 242 ARG A CZ  1 
ATOM 852  N NH1 . ARG A 1 242 ? 82.148  62.817  86.515  1.00 120.28 ? 242 ARG A NH1 1 
ATOM 853  N NH2 . ARG A 1 242 ? 81.546  64.732  87.615  1.00 122.72 ? 242 ARG A NH2 1 
ATOM 854  N N   . MET A 1 243 ? 86.459  61.919  92.992  1.00 112.44 ? 243 MET A N   1 
ATOM 855  C CA  . MET A 1 243 ? 86.822  62.469  94.294  1.00 108.88 ? 243 MET A CA  1 
ATOM 856  C C   . MET A 1 243 ? 88.334  62.558  94.454  1.00 106.80 ? 243 MET A C   1 
ATOM 857  O O   . MET A 1 243 ? 88.848  63.531  95.017  1.00 109.70 ? 243 MET A O   1 
ATOM 858  C CB  . MET A 1 243 ? 86.212  61.621  95.409  1.00 110.99 ? 243 MET A CB  1 
ATOM 859  C CG  . MET A 1 243 ? 86.500  62.133  96.807  1.00 111.06 ? 243 MET A CG  1 
ATOM 860  S SD  . MET A 1 243 ? 85.766  63.748  97.109  1.00 111.32 ? 243 MET A SD  1 
ATOM 861  C CE  . MET A 1 243 ? 84.033  63.370  96.882  1.00 107.81 ? 243 MET A CE  1 
ATOM 862  N N   . HIS A 1 244 ? 89.064  61.553  93.968  1.00 108.09 ? 244 HIS A N   1 
ATOM 863  C CA  . HIS A 1 244 ? 90.520  61.596  94.045  1.00 110.11 ? 244 HIS A CA  1 
ATOM 864  C C   . HIS A 1 244 ? 91.097  62.698  93.165  1.00 110.48 ? 244 HIS A C   1 
ATOM 865  O O   . HIS A 1 244 ? 92.177  63.221  93.460  1.00 111.98 ? 244 HIS A O   1 
ATOM 866  C CB  . HIS A 1 244 ? 91.108  60.240  93.659  1.00 113.80 ? 244 HIS A CB  1 
ATOM 867  C CG  . HIS A 1 244 ? 90.896  59.176  94.689  1.00 115.23 ? 244 HIS A CG  1 
ATOM 868  N ND1 . HIS A 1 244 ? 89.717  59.043  95.390  1.00 114.31 ? 244 HIS A ND1 1 
ATOM 869  C CD2 . HIS A 1 244 ? 91.712  58.193  95.137  1.00 112.84 ? 244 HIS A CD2 1 
ATOM 870  C CE1 . HIS A 1 244 ? 89.817  58.026  96.227  1.00 113.27 ? 244 HIS A CE1 1 
ATOM 871  N NE2 . HIS A 1 244 ? 91.017  57.493  96.093  1.00 113.92 ? 244 HIS A NE2 1 
ATOM 872  N N   . ALA A 1 245 ? 90.406  63.048  92.079  1.00 106.90 ? 245 ALA A N   1 
ATOM 873  C CA  . ALA A 1 245 ? 90.849  64.164  91.251  1.00 106.74 ? 245 ALA A CA  1 
ATOM 874  C C   . ALA A 1 245 ? 90.775  65.482  92.013  1.00 106.97 ? 245 ALA A C   1 
ATOM 875  O O   . ALA A 1 245 ? 91.671  66.325  91.896  1.00 108.46 ? 245 ALA A O   1 
ATOM 876  C CB  . ALA A 1 245 ? 90.014  64.234  89.974  1.00 109.02 ? 245 ALA A CB  1 
ATOM 877  N N   . SER A 1 246 ? 89.707  65.680  92.789  1.00 95.27  ? 246 SER A N   1 
ATOM 878  C CA  . SER A 1 246 ? 89.582  66.896  93.586  1.00 91.83  ? 246 SER A CA  1 
ATOM 879  C C   . SER A 1 246 ? 90.644  66.963  94.675  1.00 90.12  ? 246 SER A C   1 
ATOM 880  O O   . SER A 1 246 ? 91.181  68.040  94.957  1.00 90.31  ? 246 SER A O   1 
ATOM 881  C CB  . SER A 1 246 ? 88.185  66.981  94.200  1.00 91.35  ? 246 SER A CB  1 
ATOM 882  O OG  . SER A 1 246 ? 87.185  67.058  93.201  1.00 92.08  ? 246 SER A OG  1 
ATOM 883  N N   . MET A 1 247 ? 90.957  65.826  95.300  1.00 90.24  ? 247 MET A N   1 
ATOM 884  C CA  . MET A 1 247 ? 91.950  65.816  96.370  1.00 85.78  ? 247 MET A CA  1 
ATOM 885  C C   . MET A 1 247 ? 93.321  66.240  95.863  1.00 87.48  ? 247 MET A C   1 
ATOM 886  O O   . MET A 1 247 ? 94.036  66.986  96.541  1.00 91.94  ? 247 MET A O   1 
ATOM 887  C CB  . MET A 1 247 ? 92.022  64.431  97.009  1.00 87.42  ? 247 MET A CB  1 
ATOM 888  C CG  . MET A 1 247 ? 90.747  63.999  97.702  1.00 91.38  ? 247 MET A CG  1 
ATOM 889  S SD  . MET A 1 247 ? 90.882  62.363  98.440  1.00 98.27  ? 247 MET A SD  1 
ATOM 890  C CE  . MET A 1 247 ? 92.241  62.620  99.575  1.00 93.09  ? 247 MET A CE  1 
ATOM 891  N N   . LYS A 1 248 ? 93.712  65.765  94.679  1.00 84.14  ? 248 LYS A N   1 
ATOM 892  C CA  . LYS A 1 248 ? 94.993  66.172  94.113  1.00 83.23  ? 248 LYS A CA  1 
ATOM 893  C C   . LYS A 1 248 ? 95.018  67.667  93.830  1.00 84.54  ? 248 LYS A C   1 
ATOM 894  O O   . LYS A 1 248 ? 96.020  68.341  94.094  1.00 83.50  ? 248 LYS A O   1 
ATOM 895  C CB  . LYS A 1 248 ? 95.280  65.379  92.838  1.00 81.36  ? 248 LYS A CB  1 
ATOM 896  N N   . LEU A 1 249 ? 93.922  68.205  93.290  1.00 76.26  ? 249 LEU A N   1 
ATOM 897  C CA  . LEU A 1 249 ? 93.845  69.642  93.053  1.00 73.42  ? 249 LEU A CA  1 
ATOM 898  C C   . LEU A 1 249 ? 93.858  70.421  94.362  1.00 74.34  ? 249 LEU A C   1 
ATOM 899  O O   . LEU A 1 249 ? 94.514  71.464  94.462  1.00 73.06  ? 249 LEU A O   1 
ATOM 900  C CB  . LEU A 1 249 ? 92.591  69.966  92.242  1.00 70.18  ? 249 LEU A CB  1 
ATOM 901  C CG  . LEU A 1 249 ? 92.343  71.430  91.877  1.00 78.06  ? 249 LEU A CG  1 
ATOM 902  C CD1 . LEU A 1 249 ? 93.494  71.987  91.059  1.00 76.26  ? 249 LEU A CD1 1 
ATOM 903  C CD2 . LEU A 1 249 ? 91.030  71.570  91.125  1.00 70.68  ? 249 LEU A CD2 1 
ATOM 904  N N   . PHE A 1 250 ? 93.137  69.934  95.374  1.00 70.82  ? 250 PHE A N   1 
ATOM 905  C CA  . PHE A 1 250 ? 93.138  70.595  96.676  1.00 61.79  ? 250 PHE A CA  1 
ATOM 906  C C   . PHE A 1 250 ? 94.521  70.563  97.309  1.00 60.83  ? 250 PHE A C   1 
ATOM 907  O O   . PHE A 1 250 ? 94.964  71.550  97.906  1.00 69.36  ? 250 PHE A O   1 
ATOM 908  C CB  . PHE A 1 250 ? 92.115  69.932  97.597  1.00 67.04  ? 250 PHE A CB  1 
ATOM 909  C CG  . PHE A 1 250 ? 91.951  70.620  98.923  1.00 67.36  ? 250 PHE A CG  1 
ATOM 910  C CD1 . PHE A 1 250 ? 91.067  71.674  99.067  1.00 64.17  ? 250 PHE A CD1 1 
ATOM 911  C CD2 . PHE A 1 250 ? 92.676  70.209  100.025 1.00 70.51  ? 250 PHE A CD2 1 
ATOM 912  C CE1 . PHE A 1 250 ? 90.914  72.303  100.283 1.00 64.19  ? 250 PHE A CE1 1 
ATOM 913  C CE2 . PHE A 1 250 ? 92.527  70.837  101.242 1.00 66.93  ? 250 PHE A CE2 1 
ATOM 914  C CZ  . PHE A 1 250 ? 91.645  71.883  101.370 1.00 65.08  ? 250 PHE A CZ  1 
ATOM 915  N N   . ASP A 1 251 ? 95.215  69.429  97.197  1.00 68.38  ? 251 ASP A N   1 
ATOM 916  C CA  . ASP A 1 251 ? 96.555  69.313  97.762  1.00 69.60  ? 251 ASP A CA  1 
ATOM 917  C C   . ASP A 1 251 ? 97.540  70.251  97.076  1.00 68.87  ? 251 ASP A C   1 
ATOM 918  O O   . ASP A 1 251 ? 98.396  70.852  97.734  1.00 69.10  ? 251 ASP A O   1 
ATOM 919  C CB  . ASP A 1 251 ? 97.037  67.867  97.665  1.00 70.48  ? 251 ASP A CB  1 
ATOM 920  C CG  . ASP A 1 251 ? 98.487  67.710  98.070  1.00 74.56  ? 251 ASP A CG  1 
ATOM 921  O OD1 . ASP A 1 251 ? 98.789  67.861  99.271  1.00 74.02  ? 251 ASP A OD1 1 
ATOM 922  O OD2 . ASP A 1 251 ? 99.325  67.435  97.186  1.00 74.89  ? 251 ASP A OD2 1 
ATOM 923  N N   . SER A 1 252 ? 97.443  70.387  95.753  1.00 65.02  ? 252 SER A N   1 
ATOM 924  C CA  . SER A 1 252 ? 98.376  71.238  95.026  1.00 62.71  ? 252 SER A CA  1 
ATOM 925  C C   . SER A 1 252 ? 98.076  72.721  95.187  1.00 66.16  ? 252 SER A C   1 
ATOM 926  O O   . SER A 1 252 ? 98.958  73.546  94.927  1.00 71.70  ? 252 SER A O   1 
ATOM 927  C CB  . SER A 1 252 ? 98.372  70.873  93.542  1.00 66.65  ? 252 SER A CB  1 
ATOM 928  O OG  . SER A 1 252 ? 97.074  71.003  92.991  1.00 67.03  ? 252 SER A OG  1 
ATOM 929  N N   . ILE A 1 253 ? 96.865  73.078  95.602  1.00 65.22  ? 253 ILE A N   1 
ATOM 930  C CA  . ILE A 1 253 ? 96.501  74.480  95.785  1.00 60.63  ? 253 ILE A CA  1 
ATOM 931  C C   . ILE A 1 253 ? 96.703  74.918  97.227  1.00 60.06  ? 253 ILE A C   1 
ATOM 932  O O   . ILE A 1 253 ? 97.249  75.992  97.492  1.00 62.43  ? 253 ILE A O   1 
ATOM 933  C CB  . ILE A 1 253 ? 95.049  74.714  95.322  1.00 61.84  ? 253 ILE A CB  1 
ATOM 934  C CG1 . ILE A 1 253 ? 94.952  74.588  93.801  1.00 71.08  ? 253 ILE A CG1 1 
ATOM 935  C CG2 . ILE A 1 253 ? 94.556  76.072  95.786  1.00 61.16  ? 253 ILE A CG2 1 
ATOM 936  C CD1 . ILE A 1 253 ? 95.816  75.577  93.051  1.00 68.14  ? 253 ILE A CD1 1 
ATOM 937  N N   . CYS A 1 254 ? 96.260  74.095  98.179  1.00 69.54  ? 254 CYS A N   1 
ATOM 938  C CA  . CYS A 1 254 ? 96.439  74.422  99.589  1.00 70.11  ? 254 CYS A CA  1 
ATOM 939  C C   . CYS A 1 254 ? 97.915  74.479  99.956  1.00 67.84  ? 254 CYS A C   1 
ATOM 940  O O   . CYS A 1 254 ? 98.345  75.366  100.702 1.00 68.51  ? 254 CYS A O   1 
ATOM 941  C CB  . CYS A 1 254 ? 95.708  73.401  100.460 1.00 66.69  ? 254 CYS A CB  1 
ATOM 942  S SG  . CYS A 1 254 ? 95.770  73.742  102.229 1.00 74.39  ? 254 CYS A SG  1 
ATOM 943  N N   . ASN A 1 255 ? 98.706  73.548  99.434  1.00 69.17  ? 255 ASN A N   1 
ATOM 944  C CA  . ASN A 1 255 ? 100.131 73.476  99.715  1.00 70.64  ? 255 ASN A CA  1 
ATOM 945  C C   . ASN A 1 255 ? 100.964 74.262  98.713  1.00 68.77  ? 255 ASN A C   1 
ATOM 946  O O   . ASN A 1 255 ? 102.190 74.116  98.694  1.00 67.82  ? 255 ASN A O   1 
ATOM 947  C CB  . ASN A 1 255 ? 100.583 72.016  99.741  1.00 69.77  ? 255 ASN A CB  1 
ATOM 948  C CG  . ASN A 1 255 ? 99.677  71.146  100.587 1.00 72.76  ? 255 ASN A CG  1 
ATOM 949  O OD1 . ASN A 1 255 ? 99.053  71.620  101.535 1.00 72.46  ? 255 ASN A OD1 1 
ATOM 950  N ND2 . ASN A 1 255 ? 99.593  69.868  100.243 1.00 71.74  ? 255 ASN A ND2 1 
ATOM 951  N N   . ASN A 1 256 ? 100.327 75.077  97.879  1.00 64.44  ? 256 ASN A N   1 
ATOM 952  C CA  . ASN A 1 256 ? 101.048 75.878  96.904  1.00 61.87  ? 256 ASN A CA  1 
ATOM 953  C C   . ASN A 1 256 ? 101.893 76.928  97.614  1.00 62.50  ? 256 ASN A C   1 
ATOM 954  O O   . ASN A 1 256 ? 101.543 77.410  98.694  1.00 61.93  ? 256 ASN A O   1 
ATOM 955  C CB  . ASN A 1 256 ? 100.067 76.549  95.944  1.00 61.20  ? 256 ASN A CB  1 
ATOM 956  C CG  . ASN A 1 256 ? 100.716 76.966  94.646  1.00 67.19  ? 256 ASN A CG  1 
ATOM 957  O OD1 . ASN A 1 256 ? 101.333 78.024  94.560  1.00 66.82  ? 256 ASN A OD1 1 
ATOM 958  N ND2 . ASN A 1 256 ? 100.575 76.134  93.623  1.00 64.38  ? 256 ASN A ND2 1 
ATOM 959  N N   . LYS A 1 257 ? 103.026 77.276  97.001  1.00 55.05  ? 257 LYS A N   1 
ATOM 960  C CA  . LYS A 1 257 ? 103.939 78.217  97.641  1.00 56.02  ? 257 LYS A CA  1 
ATOM 961  C C   . LYS A 1 257 ? 103.340 79.613  97.741  1.00 59.45  ? 257 LYS A C   1 
ATOM 962  O O   . LYS A 1 257 ? 103.726 80.387  98.624  1.00 56.89  ? 257 LYS A O   1 
ATOM 963  C CB  . LYS A 1 257 ? 105.268 78.260  96.888  1.00 56.72  ? 257 LYS A CB  1 
ATOM 964  C CG  . LYS A 1 257 ? 105.145 78.565  95.408  1.00 63.46  ? 257 LYS A CG  1 
ATOM 965  C CD  . LYS A 1 257 ? 106.506 78.514  94.732  1.00 61.67  ? 257 LYS A CD  1 
ATOM 966  C CE  . LYS A 1 257 ? 106.394 78.760  93.239  1.00 62.56  ? 257 LYS A CE  1 
ATOM 967  N NZ  . LYS A 1 257 ? 107.724 78.725  92.573  1.00 61.02  ? 257 LYS A NZ  1 
ATOM 968  N N   . TRP A 1 258 ? 102.405 79.955  96.857  1.00 56.48  ? 258 TRP A N   1 
ATOM 969  C CA  . TRP A 1 258 ? 101.761 81.260  96.905  1.00 50.48  ? 258 TRP A CA  1 
ATOM 970  C C   . TRP A 1 258 ? 100.605 81.309  97.890  1.00 49.49  ? 258 TRP A C   1 
ATOM 971  O O   . TRP A 1 258 ? 100.088 82.397  98.159  1.00 53.76  ? 258 TRP A O   1 
ATOM 972  C CB  . TRP A 1 258 ? 101.256 81.652  95.515  1.00 57.49  ? 258 TRP A CB  1 
ATOM 973  C CG  . TRP A 1 258 ? 102.290 81.516  94.446  1.00 55.95  ? 258 TRP A CG  1 
ATOM 974  C CD1 . TRP A 1 258 ? 102.283 80.633  93.410  1.00 55.21  ? 258 TRP A CD1 1 
ATOM 975  C CD2 . TRP A 1 258 ? 103.501 82.264  94.327  1.00 45.32  ? 258 TRP A CD2 1 
ATOM 976  N NE1 . TRP A 1 258 ? 103.406 80.796  92.641  1.00 50.62  ? 258 TRP A NE1 1 
ATOM 977  C CE2 . TRP A 1 258 ? 104.173 81.791  93.186  1.00 51.94  ? 258 TRP A CE2 1 
ATOM 978  C CE3 . TRP A 1 258 ? 104.080 83.294  95.072  1.00 42.60  ? 258 TRP A CE3 1 
ATOM 979  C CZ2 . TRP A 1 258 ? 105.392 82.311  92.771  1.00 54.05  ? 258 TRP A CZ2 1 
ATOM 980  C CZ3 . TRP A 1 258 ? 105.289 83.806  94.660  1.00 50.96  ? 258 TRP A CZ3 1 
ATOM 981  C CH2 . TRP A 1 258 ? 105.934 83.315  93.520  1.00 55.72  ? 258 TRP A CH2 1 
ATOM 982  N N   . PHE A 1 259 ? 100.194 80.168  98.429  1.00 51.35  ? 259 PHE A N   1 
ATOM 983  C CA  . PHE A 1 259 ? 99.070  80.073  99.349  1.00 53.70  ? 259 PHE A CA  1 
ATOM 984  C C   . PHE A 1 259 ? 99.496  79.457  100.674 1.00 59.43  ? 259 PHE A C   1 
ATOM 985  O O   . PHE A 1 259 ? 98.784  78.641  101.257 1.00 66.73  ? 259 PHE A O   1 
ATOM 986  C CB  . PHE A 1 259 ? 97.938  79.269  98.719  1.00 52.94  ? 259 PHE A CB  1 
ATOM 987  C CG  . PHE A 1 259 ? 97.469  79.820  97.408  1.00 54.66  ? 259 PHE A CG  1 
ATOM 988  C CD1 . PHE A 1 259 ? 97.238  81.175  97.257  1.00 51.00  ? 259 PHE A CD1 1 
ATOM 989  C CD2 . PHE A 1 259 ? 97.293  78.991  96.318  1.00 54.93  ? 259 PHE A CD2 1 
ATOM 990  C CE1 . PHE A 1 259 ? 96.816  81.687  96.052  1.00 46.29  ? 259 PHE A CE1 1 
ATOM 991  C CE2 . PHE A 1 259 ? 96.874  79.498  95.110  1.00 54.32  ? 259 PHE A CE2 1 
ATOM 992  C CZ  . PHE A 1 259 ? 96.635  80.849  94.977  1.00 52.48  ? 259 PHE A CZ  1 
ATOM 993  N N   . THR A 1 260 ? 100.680 79.835  101.160 1.00 59.20  ? 260 THR A N   1 
ATOM 994  C CA  . THR A 1 260 ? 101.164 79.292  102.424 1.00 60.29  ? 260 THR A CA  1 
ATOM 995  C C   . THR A 1 260 ? 100.288 79.740  103.586 1.00 61.95  ? 260 THR A C   1 
ATOM 996  O O   . THR A 1 260 ? 99.956  78.940  104.468 1.00 65.86  ? 260 THR A O   1 
ATOM 997  C CB  . THR A 1 260 ? 102.614 79.710  102.655 1.00 63.06  ? 260 THR A CB  1 
ATOM 998  O OG1 . THR A 1 260 ? 103.430 79.218  101.586 1.00 70.03  ? 260 THR A OG1 1 
ATOM 999  C CG2 . THR A 1 260 ? 103.127 79.149  103.968 1.00 62.30  ? 260 THR A CG2 1 
ATOM 1000 N N   . ASP A 1 261 ? 99.897  81.010  103.600 1.00 62.50  ? 261 ASP A N   1 
ATOM 1001 C CA  . ASP A 1 261 ? 99.125  81.587  104.692 1.00 64.40  ? 261 ASP A CA  1 
ATOM 1002 C C   . ASP A 1 261 ? 97.772  82.097  104.210 1.00 59.64  ? 261 ASP A C   1 
ATOM 1003 O O   . ASP A 1 261 ? 97.245  83.076  104.741 1.00 62.19  ? 261 ASP A O   1 
ATOM 1004 C CB  . ASP A 1 261 ? 99.913  82.704  105.373 1.00 63.90  ? 261 ASP A CB  1 
ATOM 1005 C CG  . ASP A 1 261 ? 100.494 83.694  104.383 1.00 67.54  ? 261 ASP A CG  1 
ATOM 1006 O OD1 . ASP A 1 261 ? 100.344 83.475  103.163 1.00 63.68  ? 261 ASP A OD1 1 
ATOM 1007 O OD2 . ASP A 1 261 ? 101.103 84.690  104.826 1.00 66.56  ? 261 ASP A OD2 1 
ATOM 1008 N N   . THR A 1 262 ? 97.200  81.439  103.207 1.00 53.47  ? 262 THR A N   1 
ATOM 1009 C CA  . THR A 1 262 ? 95.899  81.802  102.662 1.00 56.28  ? 262 THR A CA  1 
ATOM 1010 C C   . THR A 1 262 ? 94.874  80.781  103.134 1.00 54.08  ? 262 THR A C   1 
ATOM 1011 O O   . THR A 1 262 ? 95.010  79.587  102.853 1.00 60.67  ? 262 THR A O   1 
ATOM 1012 C CB  . THR A 1 262 ? 95.934  81.860  101.135 1.00 49.53  ? 262 THR A CB  1 
ATOM 1013 O OG1 . THR A 1 262 ? 96.839  82.886  100.715 1.00 57.90  ? 262 THR A OG1 1 
ATOM 1014 C CG2 . THR A 1 262 ? 94.554  82.160  100.584 1.00 49.82  ? 262 THR A CG2 1 
ATOM 1015 N N   . SER A 1 263 ? 93.855  81.253  103.844 1.00 52.55  ? 263 SER A N   1 
ATOM 1016 C CA  . SER A 1 263 ? 92.803  80.372  104.317 1.00 48.56  ? 263 SER A CA  1 
ATOM 1017 C C   . SER A 1 263 ? 91.958  79.876  103.149 1.00 47.09  ? 263 SER A C   1 
ATOM 1018 O O   . SER A 1 263 ? 91.889  80.497  102.086 1.00 55.59  ? 263 SER A O   1 
ATOM 1019 C CB  . SER A 1 263 ? 91.922  81.086  105.338 1.00 51.58  ? 263 SER A CB  1 
ATOM 1020 O OG  . SER A 1 263 ? 92.673  81.464  106.477 1.00 57.10  ? 263 SER A OG  1 
ATOM 1021 N N   . ILE A 1 264 ? 91.315  78.733  103.357 1.00 40.48  ? 264 ILE A N   1 
ATOM 1022 C CA  . ILE A 1 264 ? 90.502  78.087  102.336 1.00 44.06  ? 264 ILE A CA  1 
ATOM 1023 C C   . ILE A 1 264 ? 89.111  77.856  102.900 1.00 43.65  ? 264 ILE A C   1 
ATOM 1024 O O   . ILE A 1 264 ? 88.966  77.334  104.009 1.00 57.25  ? 264 ILE A O   1 
ATOM 1025 C CB  . ILE A 1 264 ? 91.128  76.761  101.868 1.00 41.34  ? 264 ILE A CB  1 
ATOM 1026 C CG1 . ILE A 1 264 ? 92.441  77.033  101.141 1.00 35.88  ? 264 ILE A CG1 1 
ATOM 1027 C CG2 . ILE A 1 264 ? 90.169  75.998  100.973 1.00 44.85  ? 264 ILE A CG2 1 
ATOM 1028 C CD1 . ILE A 1 264 ? 93.059  75.808  100.549 1.00 44.16  ? 264 ILE A CD1 1 
ATOM 1029 N N   . ILE A 1 265 ? 88.094  78.251  102.144 1.00 37.22  ? 265 ILE A N   1 
ATOM 1030 C CA  . ILE A 1 265 ? 86.702  78.005  102.494 1.00 45.23  ? 265 ILE A CA  1 
ATOM 1031 C C   . ILE A 1 265 ? 86.251  76.805  101.672 1.00 49.56  ? 265 ILE A C   1 
ATOM 1032 O O   . ILE A 1 265 ? 85.994  76.921  100.473 1.00 63.41  ? 265 ILE A O   1 
ATOM 1033 C CB  . ILE A 1 265 ? 85.828  79.233  102.231 1.00 45.63  ? 265 ILE A CB  1 
ATOM 1034 C CG1 . ILE A 1 265 ? 86.360  80.439  103.000 1.00 43.70  ? 265 ILE A CG1 1 
ATOM 1035 C CG2 . ILE A 1 265 ? 84.388  78.953  102.609 1.00 45.27  ? 265 ILE A CG2 1 
ATOM 1036 C CD1 . ILE A 1 265 ? 85.597  81.702  102.734 1.00 47.60  ? 265 ILE A CD1 1 
ATOM 1037 N N   . LEU A 1 266 ? 86.144  75.648  102.317 1.00 55.05  ? 266 LEU A N   1 
ATOM 1038 C CA  . LEU A 1 266 ? 85.842  74.403  101.626 1.00 48.59  ? 266 LEU A CA  1 
ATOM 1039 C C   . LEU A 1 266 ? 84.333  74.215  101.549 1.00 52.05  ? 266 LEU A C   1 
ATOM 1040 O O   . LEU A 1 266 ? 83.655  74.160  102.579 1.00 60.59  ? 266 LEU A O   1 
ATOM 1041 C CB  . LEU A 1 266 ? 86.494  73.219  102.334 1.00 55.70  ? 266 LEU A CB  1 
ATOM 1042 C CG  . LEU A 1 266 ? 86.255  71.850  101.700 1.00 55.10  ? 266 LEU A CG  1 
ATOM 1043 C CD1 . LEU A 1 266 ? 86.789  71.823  100.284 1.00 61.44  ? 266 LEU A CD1 1 
ATOM 1044 C CD2 . LEU A 1 266 ? 86.899  70.761  102.535 1.00 61.69  ? 266 LEU A CD2 1 
ATOM 1045 N N   . PHE A 1 267 ? 83.811  74.124  100.330 1.00 67.65  ? 267 PHE A N   1 
ATOM 1046 C CA  . PHE A 1 267 ? 82.401  73.857  100.089 1.00 68.99  ? 267 PHE A CA  1 
ATOM 1047 C C   . PHE A 1 267 ? 82.243  72.424  99.609  1.00 72.66  ? 267 PHE A C   1 
ATOM 1048 O O   . PHE A 1 267 ? 82.910  72.008  98.657  1.00 76.27  ? 267 PHE A O   1 
ATOM 1049 C CB  . PHE A 1 267 ? 81.822  74.820  99.051  1.00 71.35  ? 267 PHE A CB  1 
ATOM 1050 C CG  . PHE A 1 267 ? 81.350  76.123  99.620  1.00 71.05  ? 267 PHE A CG  1 
ATOM 1051 C CD1 . PHE A 1 267 ? 81.204  76.290  100.983 1.00 73.54  ? 267 PHE A CD1 1 
ATOM 1052 C CD2 . PHE A 1 267 ? 81.042  77.181  98.788  1.00 72.21  ? 267 PHE A CD2 1 
ATOM 1053 C CE1 . PHE A 1 267 ? 80.764  77.489  101.502 1.00 74.55  ? 267 PHE A CE1 1 
ATOM 1054 C CE2 . PHE A 1 267 ? 80.603  78.380  99.303  1.00 73.97  ? 267 PHE A CE2 1 
ATOM 1055 C CZ  . PHE A 1 267 ? 80.464  78.534  100.660 1.00 73.74  ? 267 PHE A CZ  1 
ATOM 1056 N N   . LEU A 1 268 ? 81.367  71.676  100.267 1.00 79.89  ? 268 LEU A N   1 
ATOM 1057 C CA  . LEU A 1 268 ? 81.059  70.299  99.896  1.00 77.53  ? 268 LEU A CA  1 
ATOM 1058 C C   . LEU A 1 268 ? 79.630  70.292  99.357  1.00 84.99  ? 268 LEU A C   1 
ATOM 1059 O O   . LEU A 1 268 ? 78.666  70.135  100.107 1.00 90.27  ? 268 LEU A O   1 
ATOM 1060 C CB  . LEU A 1 268 ? 81.236  69.367  101.085 1.00 77.58  ? 268 LEU A CB  1 
ATOM 1061 C CG  . LEU A 1 268 ? 82.657  69.351  101.649 1.00 79.48  ? 268 LEU A CG  1 
ATOM 1062 C CD1 . LEU A 1 268 ? 82.776  68.398  102.818 1.00 81.49  ? 268 LEU A CD1 1 
ATOM 1063 C CD2 . LEU A 1 268 ? 83.646  68.979  100.566 1.00 81.31  ? 268 LEU A CD2 1 
ATOM 1064 N N   . ASN A 1 269 ? 79.505  70.465  98.044  1.00 94.95  ? 269 ASN A N   1 
ATOM 1065 C CA  . ASN A 1 269 ? 78.210  70.619  97.401  1.00 94.15  ? 269 ASN A CA  1 
ATOM 1066 C C   . ASN A 1 269 ? 77.557  69.261  97.156  1.00 96.11  ? 269 ASN A C   1 
ATOM 1067 O O   . ASN A 1 269 ? 78.143  68.202  97.396  1.00 97.30  ? 269 ASN A O   1 
ATOM 1068 C CB  . ASN A 1 269 ? 78.362  71.388  96.092  1.00 94.00  ? 269 ASN A CB  1 
ATOM 1069 C CG  . ASN A 1 269 ? 79.020  72.735  96.285  1.00 96.64  ? 269 ASN A CG  1 
ATOM 1070 O OD1 . ASN A 1 269 ? 78.350  73.737  96.527  1.00 98.59  ? 269 ASN A OD1 1 
ATOM 1071 N ND2 . ASN A 1 269 ? 80.342  72.766  96.180  1.00 94.58  ? 269 ASN A ND2 1 
ATOM 1072 N N   . LYS A 1 270 ? 76.318  69.306  96.659  1.00 111.29 ? 270 LYS A N   1 
ATOM 1073 C CA  . LYS A 1 270 ? 75.535  68.111  96.342  1.00 111.87 ? 270 LYS A CA  1 
ATOM 1074 C C   . LYS A 1 270 ? 75.383  67.209  97.566  1.00 111.92 ? 270 LYS A C   1 
ATOM 1075 O O   . LYS A 1 270 ? 75.574  65.994  97.503  1.00 113.36 ? 270 LYS A O   1 
ATOM 1076 C CB  . LYS A 1 270 ? 76.150  67.353  95.164  1.00 112.32 ? 270 LYS A CB  1 
ATOM 1077 C CG  . LYS A 1 270 ? 76.272  68.195  93.903  1.00 109.60 ? 270 LYS A CG  1 
ATOM 1078 C CD  . LYS A 1 270 ? 76.952  67.431  92.785  1.00 111.87 ? 270 LYS A CD  1 
ATOM 1079 C CE  . LYS A 1 270 ? 77.060  68.277  91.530  1.00 111.56 ? 270 LYS A CE  1 
ATOM 1080 N NZ  . LYS A 1 270 ? 77.718  67.535  90.420  1.00 110.65 ? 270 LYS A NZ  1 
ATOM 1081 N N   . LYS A 1 271 ? 75.038  67.828  98.696  1.00 117.88 ? 271 LYS A N   1 
ATOM 1082 C CA  . LYS A 1 271 ? 74.833  67.075  99.929  1.00 118.34 ? 271 LYS A CA  1 
ATOM 1083 C C   . LYS A 1 271 ? 73.676  66.092  99.793  1.00 120.48 ? 271 LYS A C   1 
ATOM 1084 O O   . LYS A 1 271 ? 73.787  64.927  100.190 1.00 119.10 ? 271 LYS A O   1 
ATOM 1085 C CB  . LYS A 1 271 ? 74.583  68.044  101.084 1.00 117.54 ? 271 LYS A CB  1 
ATOM 1086 C CG  . LYS A 1 271 ? 73.937  67.413  102.300 1.00 119.61 ? 271 LYS A CG  1 
ATOM 1087 C CD  . LYS A 1 271 ? 72.999  68.394  102.983 1.00 118.32 ? 271 LYS A CD  1 
ATOM 1088 C CE  . LYS A 1 271 ? 73.760  69.545  103.613 1.00 118.37 ? 271 LYS A CE  1 
ATOM 1089 N NZ  . LYS A 1 271 ? 74.586  69.080  104.758 1.00 119.36 ? 271 LYS A NZ  1 
ATOM 1090 N N   . ASP A 1 272 ? 72.553  66.548  99.233  1.00 128.31 ? 272 ASP A N   1 
ATOM 1091 C CA  . ASP A 1 272 ? 71.384  65.682  99.113  1.00 127.23 ? 272 ASP A CA  1 
ATOM 1092 C C   . ASP A 1 272 ? 71.638  64.531  98.147  1.00 127.33 ? 272 ASP A C   1 
ATOM 1093 O O   . ASP A 1 272 ? 71.226  63.394  98.406  1.00 127.58 ? 272 ASP A O   1 
ATOM 1094 C CB  . ASP A 1 272 ? 70.170  66.498  98.671  1.00 127.84 ? 272 ASP A CB  1 
ATOM 1095 C CG  . ASP A 1 272 ? 70.430  67.288  97.405  1.00 129.32 ? 272 ASP A CG  1 
ATOM 1096 O OD1 . ASP A 1 272 ? 71.598  67.655  97.163  1.00 130.02 ? 272 ASP A OD1 1 
ATOM 1097 O OD2 . ASP A 1 272 ? 69.466  67.542  96.653  1.00 128.83 ? 272 ASP A OD2 1 
ATOM 1098 N N   . LEU A 1 273 ? 72.314  64.804  97.030  1.00 127.62 ? 273 LEU A N   1 
ATOM 1099 C CA  . LEU A 1 273 ? 72.606  63.750  96.064  1.00 128.60 ? 273 LEU A CA  1 
ATOM 1100 C C   . LEU A 1 273 ? 73.576  62.725  96.637  1.00 128.41 ? 273 LEU A C   1 
ATOM 1101 O O   . LEU A 1 273 ? 73.464  61.528  96.348  1.00 129.79 ? 273 LEU A O   1 
ATOM 1102 C CB  . LEU A 1 273 ? 73.161  64.361  94.778  1.00 129.19 ? 273 LEU A CB  1 
ATOM 1103 C CG  . LEU A 1 273 ? 73.365  63.409  93.600  1.00 130.15 ? 273 LEU A CG  1 
ATOM 1104 C CD1 . LEU A 1 273 ? 72.058  62.729  93.232  1.00 128.23 ? 273 LEU A CD1 1 
ATOM 1105 C CD2 . LEU A 1 273 ? 73.939  64.157  92.408  1.00 126.85 ? 273 LEU A CD2 1 
ATOM 1106 N N   . PHE A 1 274 ? 74.537  63.175  97.445  1.00 125.14 ? 274 PHE A N   1 
ATOM 1107 C CA  . PHE A 1 274 ? 75.476  62.250  98.071  1.00 123.97 ? 274 PHE A CA  1 
ATOM 1108 C C   . PHE A 1 274 ? 74.767  61.312  99.038  1.00 126.36 ? 274 PHE A C   1 
ATOM 1109 O O   . PHE A 1 274 ? 75.102  60.125  99.121  1.00 128.83 ? 274 PHE A O   1 
ATOM 1110 C CB  . PHE A 1 274 ? 76.576  63.031  98.789  1.00 125.79 ? 274 PHE A CB  1 
ATOM 1111 C CG  . PHE A 1 274 ? 77.471  62.179  99.641  1.00 124.38 ? 274 PHE A CG  1 
ATOM 1112 C CD1 . PHE A 1 274 ? 78.478  61.422  99.069  1.00 124.71 ? 274 PHE A CD1 1 
ATOM 1113 C CD2 . PHE A 1 274 ? 77.314  62.145  101.015 1.00 124.75 ? 274 PHE A CD2 1 
ATOM 1114 C CE1 . PHE A 1 274 ? 79.307  60.642  99.850  1.00 124.66 ? 274 PHE A CE1 1 
ATOM 1115 C CE2 . PHE A 1 274 ? 78.140  61.367  101.801 1.00 125.49 ? 274 PHE A CE2 1 
ATOM 1116 C CZ  . PHE A 1 274 ? 79.138  60.614  101.217 1.00 125.68 ? 274 PHE A CZ  1 
ATOM 1117 N N   . GLU A 1 275 ? 73.791  61.829  99.788  1.00 131.88 ? 275 GLU A N   1 
ATOM 1118 C CA  . GLU A 1 275 ? 73.066  60.991  100.738 1.00 132.59 ? 275 GLU A CA  1 
ATOM 1119 C C   . GLU A 1 275 ? 72.291  59.889  100.025 1.00 131.92 ? 275 GLU A C   1 
ATOM 1120 O O   . GLU A 1 275 ? 72.236  58.750  100.502 1.00 130.98 ? 275 GLU A O   1 
ATOM 1121 C CB  . GLU A 1 275 ? 72.125  61.849  101.582 1.00 131.97 ? 275 GLU A CB  1 
ATOM 1122 C CG  . GLU A 1 275 ? 71.373  61.077  102.652 1.00 131.65 ? 275 GLU A CG  1 
ATOM 1123 C CD  . GLU A 1 275 ? 70.498  61.969  103.508 1.00 132.33 ? 275 GLU A CD  1 
ATOM 1124 O OE1 . GLU A 1 275 ? 70.490  63.196  103.275 1.00 132.05 ? 275 GLU A OE1 1 
ATOM 1125 O OE2 . GLU A 1 275 ? 69.817  61.444  104.413 1.00 132.10 ? 275 GLU A OE2 1 
ATOM 1126 N N   . GLU A 1 276 ? 71.673  60.212  98.888  1.00 134.02 ? 276 GLU A N   1 
ATOM 1127 C CA  . GLU A 1 276 ? 70.943  59.197  98.136  1.00 133.07 ? 276 GLU A CA  1 
ATOM 1128 C C   . GLU A 1 276 ? 71.880  58.124  97.596  1.00 132.36 ? 276 GLU A C   1 
ATOM 1129 O O   . GLU A 1 276 ? 71.556  56.932  97.639  1.00 133.50 ? 276 GLU A O   1 
ATOM 1130 C CB  . GLU A 1 276 ? 70.161  59.851  96.998  1.00 133.24 ? 276 GLU A CB  1 
ATOM 1131 C CG  . GLU A 1 276 ? 69.161  60.898  97.455  1.00 134.04 ? 276 GLU A CG  1 
ATOM 1132 C CD  . GLU A 1 276 ? 68.421  61.540  96.299  1.00 135.14 ? 276 GLU A CD  1 
ATOM 1133 O OE1 . GLU A 1 276 ? 68.676  61.152  95.139  1.00 135.08 ? 276 GLU A OE1 1 
ATOM 1134 O OE2 . GLU A 1 276 ? 67.583  62.432  96.549  1.00 133.90 ? 276 GLU A OE2 1 
ATOM 1135 N N   . LYS A 1 277 ? 73.047  58.525  97.087  1.00 134.82 ? 277 LYS A N   1 
ATOM 1136 C CA  . LYS A 1 277 ? 73.966  57.556  96.502  1.00 135.80 ? 277 LYS A CA  1 
ATOM 1137 C C   . LYS A 1 277 ? 74.631  56.683  97.558  1.00 136.60 ? 277 LYS A C   1 
ATOM 1138 O O   . LYS A 1 277 ? 74.937  55.517  97.288  1.00 137.00 ? 277 LYS A O   1 
ATOM 1139 C CB  . LYS A 1 277 ? 75.033  58.273  95.673  1.00 135.71 ? 277 LYS A CB  1 
ATOM 1140 C CG  . LYS A 1 277 ? 74.499  58.986  94.444  1.00 134.94 ? 277 LYS A CG  1 
ATOM 1141 C CD  . LYS A 1 277 ? 75.629  59.591  93.628  1.00 134.59 ? 277 LYS A CD  1 
ATOM 1142 C CE  . LYS A 1 277 ? 75.101  60.257  92.370  1.00 135.35 ? 277 LYS A CE  1 
ATOM 1143 N NZ  . LYS A 1 277 ? 76.195  60.842  91.548  1.00 135.81 ? 277 LYS A NZ  1 
ATOM 1144 N N   . ILE A 1 278 ? 74.867  57.222  98.757  1.00 140.31 ? 278 ILE A N   1 
ATOM 1145 C CA  . ILE A 1 278 ? 75.587  56.460  99.773  1.00 140.00 ? 278 ILE A CA  1 
ATOM 1146 C C   . ILE A 1 278 ? 74.758  55.276  100.256 1.00 141.74 ? 278 ILE A C   1 
ATOM 1147 O O   . ILE A 1 278 ? 75.310  54.274  100.725 1.00 141.11 ? 278 ILE A O   1 
ATOM 1148 C CB  . ILE A 1 278 ? 76.013  57.377  100.937 1.00 139.48 ? 278 ILE A CB  1 
ATOM 1149 C CG1 . ILE A 1 278 ? 77.145  56.732  101.736 1.00 140.10 ? 278 ILE A CG1 1 
ATOM 1150 C CG2 . ILE A 1 278 ? 74.844  57.677  101.854 1.00 139.39 ? 278 ILE A CG2 1 
ATOM 1151 C CD1 . ILE A 1 278 ? 78.389  56.473  100.923 1.00 140.74 ? 278 ILE A CD1 1 
ATOM 1152 N N   . LYS A 1 279 ? 73.429  55.364  100.154 1.00 149.81 ? 279 LYS A N   1 
ATOM 1153 C CA  . LYS A 1 279 ? 72.582  54.237  100.531 1.00 148.65 ? 279 LYS A CA  1 
ATOM 1154 C C   . LYS A 1 279 ? 72.807  53.044  99.610  1.00 148.15 ? 279 LYS A C   1 
ATOM 1155 O O   . LYS A 1 279 ? 72.878  51.900  100.072 1.00 146.43 ? 279 LYS A O   1 
ATOM 1156 C CB  . LYS A 1 279 ? 71.113  54.657  100.519 1.00 146.51 ? 279 LYS A CB  1 
ATOM 1157 N N   . LYS A 1 280 ? 72.922  53.291  98.306  1.00 147.98 ? 280 LYS A N   1 
ATOM 1158 C CA  . LYS A 1 280 ? 73.124  52.222  97.337  1.00 146.58 ? 280 LYS A CA  1 
ATOM 1159 C C   . LYS A 1 280 ? 74.604  51.928  97.114  1.00 147.53 ? 280 LYS A C   1 
ATOM 1160 O O   . LYS A 1 280 ? 75.024  50.768  97.166  1.00 147.38 ? 280 LYS A O   1 
ATOM 1161 C CB  . LYS A 1 280 ? 72.450  52.582  96.010  1.00 145.77 ? 280 LYS A CB  1 
ATOM 1162 N N   . SER A 1 281 ? 75.404  52.965  96.866  1.00 149.51 ? 281 SER A N   1 
ATOM 1163 C CA  . SER A 1 281 ? 76.825  52.789  96.611  1.00 148.89 ? 281 SER A CA  1 
ATOM 1164 C C   . SER A 1 281 ? 77.607  53.126  97.870  1.00 149.40 ? 281 SER A C   1 
ATOM 1165 O O   . SER A 1 281 ? 77.642  54.301  98.268  1.00 148.50 ? 281 SER A O   1 
ATOM 1166 C CB  . SER A 1 281 ? 77.276  53.673  95.451  1.00 148.39 ? 281 SER A CB  1 
ATOM 1167 O OG  . SER A 1 281 ? 78.660  53.510  95.197  1.00 148.56 ? 281 SER A OG  1 
ATOM 1168 N N   . PRO A 1 282 ? 78.238  52.157  98.525  1.00 149.18 ? 282 PRO A N   1 
ATOM 1169 C CA  . PRO A 1 282 ? 78.996  52.458  99.744  1.00 148.68 ? 282 PRO A CA  1 
ATOM 1170 C C   . PRO A 1 282 ? 80.246  53.272  99.446  1.00 148.62 ? 282 PRO A C   1 
ATOM 1171 O O   . PRO A 1 282 ? 80.794  53.252  98.342  1.00 148.37 ? 282 PRO A O   1 
ATOM 1172 C CB  . PRO A 1 282 ? 79.353  51.073  100.291 1.00 147.72 ? 282 PRO A CB  1 
ATOM 1173 C CG  . PRO A 1 282 ? 79.360  50.192  99.086  1.00 147.84 ? 282 PRO A CG  1 
ATOM 1174 C CD  . PRO A 1 282 ? 78.285  50.725  98.181  1.00 147.59 ? 282 PRO A CD  1 
ATOM 1175 N N   . LEU A 1 283 ? 80.697  54.001  100.470 1.00 142.49 ? 283 LEU A N   1 
ATOM 1176 C CA  . LEU A 1 283 ? 81.897  54.821  100.356 1.00 142.55 ? 283 LEU A CA  1 
ATOM 1177 C C   . LEU A 1 283 ? 83.163  53.992  100.188 1.00 143.01 ? 283 LEU A C   1 
ATOM 1178 O O   . LEU A 1 283 ? 84.197  54.545  99.798  1.00 142.42 ? 283 LEU A O   1 
ATOM 1179 C CB  . LEU A 1 283 ? 82.026  55.729  101.583 1.00 142.86 ? 283 LEU A CB  1 
ATOM 1180 C CG  . LEU A 1 283 ? 83.063  56.854  101.521 1.00 142.73 ? 283 LEU A CG  1 
ATOM 1181 C CD1 . LEU A 1 283 ? 82.791  57.766  100.339 1.00 142.61 ? 283 LEU A CD1 1 
ATOM 1182 C CD2 . LEU A 1 283 ? 83.082  57.646  102.816 1.00 141.99 ? 283 LEU A CD2 1 
ATOM 1183 N N   . THR A 1 284 ? 83.107  52.686  100.459 1.00 145.29 ? 284 THR A N   1 
ATOM 1184 C CA  . THR A 1 284 ? 84.288  51.842  100.317 1.00 145.17 ? 284 THR A CA  1 
ATOM 1185 C C   . THR A 1 284 ? 84.808  51.811  98.886  1.00 144.34 ? 284 THR A C   1 
ATOM 1186 O O   . THR A 1 284 ? 85.991  51.519  98.676  1.00 143.26 ? 284 THR A O   1 
ATOM 1187 C CB  . THR A 1 284 ? 83.978  50.419  100.784 1.00 145.11 ? 284 THR A CB  1 
ATOM 1188 O OG1 . THR A 1 284 ? 82.924  49.871  99.983  1.00 144.67 ? 284 THR A OG1 1 
ATOM 1189 C CG2 . THR A 1 284 ? 83.547  50.422  102.243 1.00 143.74 ? 284 THR A CG2 1 
ATOM 1190 N N   . ILE A 1 285 ? 83.955  52.099  97.901  1.00 147.35 ? 285 ILE A N   1 
ATOM 1191 C CA  . ILE A 1 285 ? 84.410  52.154  96.515  1.00 147.71 ? 285 ILE A CA  1 
ATOM 1192 C C   . ILE A 1 285 ? 85.415  53.282  96.330  1.00 147.13 ? 285 ILE A C   1 
ATOM 1193 O O   . ILE A 1 285 ? 86.447  53.114  95.669  1.00 147.40 ? 285 ILE A O   1 
ATOM 1194 C CB  . ILE A 1 285 ? 83.209  52.305  95.564  1.00 147.69 ? 285 ILE A CB  1 
ATOM 1195 C CG1 . ILE A 1 285 ? 82.249  51.125  95.729  1.00 147.95 ? 285 ILE A CG1 1 
ATOM 1196 C CG2 . ILE A 1 285 ? 83.680  52.419  94.123  1.00 146.72 ? 285 ILE A CG2 1 
ATOM 1197 C CD1 . ILE A 1 285 ? 81.039  51.192  94.824  1.00 148.27 ? 285 ILE A CD1 1 
ATOM 1198 N N   . CYS A 1 286 ? 85.134  54.449  96.912  1.00 135.24 ? 286 CYS A N   1 
ATOM 1199 C CA  . CYS A 1 286 ? 86.046  55.579  96.785  1.00 134.58 ? 286 CYS A CA  1 
ATOM 1200 C C   . CYS A 1 286 ? 87.238  55.437  97.723  1.00 134.14 ? 286 CYS A C   1 
ATOM 1201 O O   . CYS A 1 286 ? 88.392  55.516  97.289  1.00 133.20 ? 286 CYS A O   1 
ATOM 1202 C CB  . CYS A 1 286 ? 85.300  56.886  97.056  1.00 134.14 ? 286 CYS A CB  1 
ATOM 1203 S SG  . CYS A 1 286 ? 86.315  58.367  96.890  1.00 134.09 ? 286 CYS A SG  1 
ATOM 1204 N N   . TYR A 1 287 ? 86.979  55.225  99.013  1.00 128.03 ? 287 TYR A N   1 
ATOM 1205 C CA  . TYR A 1 287 ? 88.037  55.043  100.001 1.00 127.44 ? 287 TYR A CA  1 
ATOM 1206 C C   . TYR A 1 287 ? 87.982  53.624  100.549 1.00 130.17 ? 287 TYR A C   1 
ATOM 1207 O O   . TYR A 1 287 ? 87.120  53.316  101.387 1.00 130.11 ? 287 TYR A O   1 
ATOM 1208 C CB  . TYR A 1 287 ? 87.903  56.062  101.136 1.00 126.93 ? 287 TYR A CB  1 
ATOM 1209 C CG  . TYR A 1 287 ? 88.087  57.497  100.700 1.00 126.64 ? 287 TYR A CG  1 
ATOM 1210 C CD1 . TYR A 1 287 ? 89.355  58.033  100.535 1.00 125.93 ? 287 TYR A CD1 1 
ATOM 1211 C CD2 . TYR A 1 287 ? 86.993  58.316  100.460 1.00 127.37 ? 287 TYR A CD2 1 
ATOM 1212 C CE1 . TYR A 1 287 ? 89.530  59.342  100.138 1.00 125.16 ? 287 TYR A CE1 1 
ATOM 1213 C CE2 . TYR A 1 287 ? 87.158  59.627  100.064 1.00 127.46 ? 287 TYR A CE2 1 
ATOM 1214 C CZ  . TYR A 1 287 ? 88.429  60.135  99.904  1.00 126.78 ? 287 TYR A CZ  1 
ATOM 1215 O OH  . TYR A 1 287 ? 88.600  61.441  99.509  1.00 126.68 ? 287 TYR A OH  1 
ATOM 1216 N N   . PRO A 1 288 ? 88.860  52.723  100.105 1.00 139.61 ? 288 PRO A N   1 
ATOM 1217 C CA  . PRO A 1 288 ? 88.842  51.355  100.649 1.00 138.72 ? 288 PRO A CA  1 
ATOM 1218 C C   . PRO A 1 288 ? 89.120  51.290  102.141 1.00 136.94 ? 288 PRO A C   1 
ATOM 1219 O O   . PRO A 1 288 ? 88.608  50.391  102.819 1.00 135.69 ? 288 PRO A O   1 
ATOM 1220 C CB  . PRO A 1 288 ? 89.935  50.644  99.839  1.00 137.88 ? 288 PRO A CB  1 
ATOM 1221 C CG  . PRO A 1 288 ? 90.839  51.742  99.380  1.00 136.49 ? 288 PRO A CG  1 
ATOM 1222 C CD  . PRO A 1 288 ? 89.947  52.921  99.132  1.00 136.74 ? 288 PRO A CD  1 
ATOM 1223 N N   . GLU A 1 289 ? 89.914  52.219  102.674 1.00 141.31 ? 289 GLU A N   1 
ATOM 1224 C CA  . GLU A 1 289 ? 90.280  52.192  104.085 1.00 141.61 ? 289 GLU A CA  1 
ATOM 1225 C C   . GLU A 1 289 ? 89.134  52.580  105.009 1.00 142.63 ? 289 GLU A C   1 
ATOM 1226 O O   . GLU A 1 289 ? 89.257  52.396  106.224 1.00 142.14 ? 289 GLU A O   1 
ATOM 1227 C CB  . GLU A 1 289 ? 91.473  53.117  104.333 1.00 141.66 ? 289 GLU A CB  1 
ATOM 1228 N N   . TYR A 1 290 ? 88.038  53.113  104.475 1.00 138.04 ? 290 TYR A N   1 
ATOM 1229 C CA  . TYR A 1 290 ? 86.915  53.510  105.312 1.00 136.00 ? 290 TYR A CA  1 
ATOM 1230 C C   . TYR A 1 290 ? 86.273  52.287  105.954 1.00 138.17 ? 290 TYR A C   1 
ATOM 1231 O O   . TYR A 1 290 ? 85.970  51.301  105.276 1.00 138.74 ? 290 TYR A O   1 
ATOM 1232 C CB  . TYR A 1 290 ? 85.890  54.280  104.483 1.00 136.14 ? 290 TYR A CB  1 
ATOM 1233 C CG  . TYR A 1 290 ? 84.685  54.750  105.264 1.00 137.27 ? 290 TYR A CG  1 
ATOM 1234 C CD1 . TYR A 1 290 ? 84.829  55.571  106.372 1.00 136.33 ? 290 TYR A CD1 1 
ATOM 1235 C CD2 . TYR A 1 290 ? 83.401  54.395  104.875 1.00 136.71 ? 290 TYR A CD2 1 
ATOM 1236 C CE1 . TYR A 1 290 ? 83.730  56.010  107.083 1.00 136.40 ? 290 TYR A CE1 1 
ATOM 1237 C CE2 . TYR A 1 290 ? 82.296  54.831  105.579 1.00 136.91 ? 290 TYR A CE2 1 
ATOM 1238 C CZ  . TYR A 1 290 ? 82.467  55.638  106.681 1.00 137.73 ? 290 TYR A CZ  1 
ATOM 1239 O OH  . TYR A 1 290 ? 81.370  56.074  107.387 1.00 137.99 ? 290 TYR A OH  1 
ATOM 1240 N N   . ALA A 1 291 ? 86.068  52.354  107.267 1.00 141.93 ? 291 ALA A N   1 
ATOM 1241 C CA  . ALA A 1 291 ? 85.508  51.247  108.035 1.00 141.63 ? 291 ALA A CA  1 
ATOM 1242 C C   . ALA A 1 291 ? 84.473  51.771  109.025 1.00 141.36 ? 291 ALA A C   1 
ATOM 1243 O O   . ALA A 1 291 ? 84.444  51.390  110.195 1.00 140.63 ? 291 ALA A O   1 
ATOM 1244 C CB  . ALA A 1 291 ? 86.610  50.467  108.749 1.00 140.11 ? 291 ALA A CB  1 
ATOM 1245 N N   . GLY A 1 292 ? 83.602  52.663  108.553 1.00 148.35 ? 292 GLY A N   1 
ATOM 1246 C CA  . GLY A 1 292 ? 82.561  53.241  109.370 1.00 148.57 ? 292 GLY A CA  1 
ATOM 1247 C C   . GLY A 1 292 ? 81.178  52.918  108.831 1.00 148.36 ? 292 GLY A C   1 
ATOM 1248 O O   . GLY A 1 292 ? 81.017  52.198  107.842 1.00 147.16 ? 292 GLY A O   1 
ATOM 1249 N N   . SER A 1 293 ? 80.176  53.466  109.513 1.00 147.58 ? 293 SER A N   1 
ATOM 1250 C CA  . SER A 1 293 ? 78.795  53.220  109.126 1.00 147.99 ? 293 SER A CA  1 
ATOM 1251 C C   . SER A 1 293 ? 78.509  53.824  107.758 1.00 148.05 ? 293 SER A C   1 
ATOM 1252 O O   . SER A 1 293 ? 79.002  54.903  107.419 1.00 149.37 ? 293 SER A O   1 
ATOM 1253 C CB  . SER A 1 293 ? 77.838  53.798  110.167 1.00 147.76 ? 293 SER A CB  1 
ATOM 1254 O OG  . SER A 1 293 ? 77.997  55.201  110.286 1.00 148.47 ? 293 SER A OG  1 
ATOM 1255 N N   . ASN A 1 294 ? 77.701  53.116  106.968 1.00 146.23 ? 294 ASN A N   1 
ATOM 1256 C CA  . ASN A 1 294 ? 77.347  53.557  105.621 1.00 146.80 ? 294 ASN A CA  1 
ATOM 1257 C C   . ASN A 1 294 ? 76.165  54.529  105.678 1.00 147.87 ? 294 ASN A C   1 
ATOM 1258 O O   . ASN A 1 294 ? 75.104  54.314  105.094 1.00 146.91 ? 294 ASN A O   1 
ATOM 1259 C CB  . ASN A 1 294 ? 77.043  52.352  104.740 1.00 146.39 ? 294 ASN A CB  1 
ATOM 1260 C CG  . ASN A 1 294 ? 77.042  52.695  103.266 1.00 147.65 ? 294 ASN A CG  1 
ATOM 1261 O OD1 . ASN A 1 294 ? 77.696  53.645  102.838 1.00 148.65 ? 294 ASN A OD1 1 
ATOM 1262 N ND2 . ASN A 1 294 ? 76.307  51.919  102.478 1.00 147.89 ? 294 ASN A ND2 1 
ATOM 1263 N N   . THR A 1 295 ? 76.374  55.623  106.408 1.00 144.36 ? 295 THR A N   1 
ATOM 1264 C CA  . THR A 1 295 ? 75.353  56.639  106.613 1.00 144.00 ? 295 THR A CA  1 
ATOM 1265 C C   . THR A 1 295 ? 75.926  58.014  106.304 1.00 143.22 ? 295 THR A C   1 
ATOM 1266 O O   . THR A 1 295 ? 77.141  58.227  106.332 1.00 142.28 ? 295 THR A O   1 
ATOM 1267 C CB  . THR A 1 295 ? 74.808  56.615  108.049 1.00 142.91 ? 295 THR A CB  1 
ATOM 1268 O OG1 . THR A 1 295 ? 75.892  56.753  108.976 1.00 142.04 ? 295 THR A OG1 1 
ATOM 1269 C CG2 . THR A 1 295 ? 74.074  55.311  108.323 1.00 141.87 ? 295 THR A CG2 1 
ATOM 1270 N N   . TYR A 1 296 ? 75.024  58.951  106.003 1.00 131.57 ? 296 TYR A N   1 
ATOM 1271 C CA  . TYR A 1 296 ? 75.443  60.305  105.654 1.00 131.22 ? 296 TYR A CA  1 
ATOM 1272 C C   . TYR A 1 296 ? 76.162  60.985  106.813 1.00 130.65 ? 296 TYR A C   1 
ATOM 1273 O O   . TYR A 1 296 ? 77.157  61.688  106.607 1.00 131.28 ? 296 TYR A O   1 
ATOM 1274 C CB  . TYR A 1 296 ? 74.234  61.132  105.217 1.00 130.60 ? 296 TYR A CB  1 
ATOM 1275 C CG  . TYR A 1 296 ? 74.477  62.624  105.230 1.00 131.56 ? 296 TYR A CG  1 
ATOM 1276 C CD1 . TYR A 1 296 ? 75.212  63.237  104.226 1.00 132.22 ? 296 TYR A CD1 1 
ATOM 1277 C CD2 . TYR A 1 296 ? 73.969  63.420  106.248 1.00 130.16 ? 296 TYR A CD2 1 
ATOM 1278 C CE1 . TYR A 1 296 ? 75.438  64.600  104.236 1.00 130.69 ? 296 TYR A CE1 1 
ATOM 1279 C CE2 . TYR A 1 296 ? 74.190  64.783  106.266 1.00 130.63 ? 296 TYR A CE2 1 
ATOM 1280 C CZ  . TYR A 1 296 ? 74.925  65.367  105.257 1.00 130.26 ? 296 TYR A CZ  1 
ATOM 1281 O OH  . TYR A 1 296 ? 75.146  66.724  105.272 1.00 129.46 ? 296 TYR A OH  1 
ATOM 1282 N N   . GLU A 1 297 ? 75.673  60.788  108.039 1.00 134.62 ? 297 GLU A N   1 
ATOM 1283 C CA  . GLU A 1 297 ? 76.249  61.473  109.191 1.00 134.35 ? 297 GLU A CA  1 
ATOM 1284 C C   . GLU A 1 297 ? 77.700  61.088  109.440 1.00 134.07 ? 297 GLU A C   1 
ATOM 1285 O O   . GLU A 1 297 ? 78.430  61.854  110.077 1.00 133.65 ? 297 GLU A O   1 
ATOM 1286 C CB  . GLU A 1 297 ? 75.416  61.188  110.442 1.00 134.58 ? 297 GLU A CB  1 
ATOM 1287 C CG  . GLU A 1 297 ? 74.009  61.759  110.395 1.00 136.09 ? 297 GLU A CG  1 
ATOM 1288 C CD  . GLU A 1 297 ? 73.989  63.274  110.452 1.00 135.80 ? 297 GLU A CD  1 
ATOM 1289 O OE1 . GLU A 1 297 ? 74.982  63.868  110.924 1.00 134.72 ? 297 GLU A OE1 1 
ATOM 1290 O OE2 . GLU A 1 297 ? 72.980  63.872  110.024 1.00 134.98 ? 297 GLU A OE2 1 
ATOM 1291 N N   . GLU A 1 298 ? 78.136  59.928  108.957 1.00 137.31 ? 298 GLU A N   1 
ATOM 1292 C CA  . GLU A 1 298 ? 79.508  59.471  109.146 1.00 137.04 ? 298 GLU A CA  1 
ATOM 1293 C C   . GLU A 1 298 ? 80.341  59.516  107.877 1.00 136.46 ? 298 GLU A C   1 
ATOM 1294 O O   . GLU A 1 298 ? 81.515  59.886  107.932 1.00 136.30 ? 298 GLU A O   1 
ATOM 1295 C CB  . GLU A 1 298 ? 79.517  58.042  109.702 1.00 136.73 ? 298 GLU A CB  1 
ATOM 1296 N N   . ALA A 1 299 ? 79.766  59.141  106.732 1.00 132.46 ? 299 ALA A N   1 
ATOM 1297 C CA  . ALA A 1 299 ? 80.523  59.173  105.484 1.00 132.67 ? 299 ALA A CA  1 
ATOM 1298 C C   . ALA A 1 299 ? 80.903  60.597  105.102 1.00 131.79 ? 299 ALA A C   1 
ATOM 1299 O O   . ALA A 1 299 ? 82.036  60.849  104.678 1.00 131.66 ? 299 ALA A O   1 
ATOM 1300 C CB  . ALA A 1 299 ? 79.721  58.512  104.364 1.00 131.83 ? 299 ALA A CB  1 
ATOM 1301 N N   . ALA A 1 300 ? 79.970  61.542  105.245 1.00 124.37 ? 300 ALA A N   1 
ATOM 1302 C CA  . ALA A 1 300 ? 80.268  62.931  104.912 1.00 123.84 ? 300 ALA A CA  1 
ATOM 1303 C C   . ALA A 1 300 ? 81.335  63.503  105.836 1.00 122.62 ? 300 ALA A C   1 
ATOM 1304 O O   . ALA A 1 300 ? 82.229  64.230  105.389 1.00 123.17 ? 300 ALA A O   1 
ATOM 1305 C CB  . ALA A 1 300 ? 78.994  63.774  104.974 1.00 123.89 ? 300 ALA A CB  1 
ATOM 1306 N N   . ALA A 1 301 ? 81.256  63.186  107.130 1.00 118.26 ? 301 ALA A N   1 
ATOM 1307 C CA  . ALA A 1 301 ? 82.278  63.644  108.063 1.00 117.32 ? 301 ALA A CA  1 
ATOM 1308 C C   . ALA A 1 301 ? 83.629  63.012  107.763 1.00 116.37 ? 301 ALA A C   1 
ATOM 1309 O O   . ALA A 1 301 ? 84.669  63.650  107.956 1.00 115.42 ? 301 ALA A O   1 
ATOM 1310 C CB  . ALA A 1 301 ? 81.854  63.342  109.499 1.00 117.30 ? 301 ALA A CB  1 
ATOM 1311 N N   . TYR A 1 302 ? 83.633  61.758  107.308 1.00 116.60 ? 302 TYR A N   1 
ATOM 1312 C CA  . TYR A 1 302 ? 84.879  61.108  106.922 1.00 115.69 ? 302 TYR A CA  1 
ATOM 1313 C C   . TYR A 1 302 ? 85.508  61.788  105.713 1.00 115.71 ? 302 TYR A C   1 
ATOM 1314 O O   . TYR A 1 302 ? 86.734  61.932  105.644 1.00 114.04 ? 302 TYR A O   1 
ATOM 1315 C CB  . TYR A 1 302 ? 84.627  59.627  106.642 1.00 117.24 ? 302 TYR A CB  1 
ATOM 1316 C CG  . TYR A 1 302 ? 85.868  58.850  106.272 1.00 117.10 ? 302 TYR A CG  1 
ATOM 1317 C CD1 . TYR A 1 302 ? 86.770  58.447  107.245 1.00 116.03 ? 302 TYR A CD1 1 
ATOM 1318 C CD2 . TYR A 1 302 ? 86.130  58.508  104.954 1.00 116.73 ? 302 TYR A CD2 1 
ATOM 1319 C CE1 . TYR A 1 302 ? 87.904  57.735  106.915 1.00 116.49 ? 302 TYR A CE1 1 
ATOM 1320 C CE2 . TYR A 1 302 ? 87.260  57.794  104.615 1.00 117.48 ? 302 TYR A CE2 1 
ATOM 1321 C CZ  . TYR A 1 302 ? 88.144  57.410  105.600 1.00 117.96 ? 302 TYR A CZ  1 
ATOM 1322 O OH  . TYR A 1 302 ? 89.274  56.700  105.268 1.00 117.11 ? 302 TYR A OH  1 
ATOM 1323 N N   . ILE A 1 303 ? 84.688  62.205  104.745 1.00 109.86 ? 303 ILE A N   1 
ATOM 1324 C CA  . ILE A 1 303 ? 85.212  62.915  103.582 1.00 108.43 ? 303 ILE A CA  1 
ATOM 1325 C C   . ILE A 1 303 ? 85.796  64.260  103.995 1.00 107.36 ? 303 ILE A C   1 
ATOM 1326 O O   . ILE A 1 303 ? 86.825  64.695  103.463 1.00 107.49 ? 303 ILE A O   1 
ATOM 1327 C CB  . ILE A 1 303 ? 84.114  63.075  102.514 1.00 106.01 ? 303 ILE A CB  1 
ATOM 1328 C CG1 . ILE A 1 303 ? 83.665  61.707  102.002 1.00 106.53 ? 303 ILE A CG1 1 
ATOM 1329 C CG2 . ILE A 1 303 ? 84.601  63.937  101.362 1.00 106.52 ? 303 ILE A CG2 1 
ATOM 1330 C CD1 . ILE A 1 303 ? 82.628  61.781  100.908 1.00 107.40 ? 303 ILE A CD1 1 
ATOM 1331 N N   . GLN A 1 304 ? 85.156  64.937  104.950 1.00 93.41  ? 304 GLN A N   1 
ATOM 1332 C CA  . GLN A 1 304 ? 85.663  66.224  105.414 1.00 90.77  ? 304 GLN A CA  1 
ATOM 1333 C C   . GLN A 1 304 ? 87.054  66.089  106.017 1.00 92.53  ? 304 GLN A C   1 
ATOM 1334 O O   . GLN A 1 304 ? 87.935  66.915  105.756 1.00 94.16  ? 304 GLN A O   1 
ATOM 1335 C CB  . GLN A 1 304 ? 84.698  66.828  106.431 1.00 91.60  ? 304 GLN A CB  1 
ATOM 1336 C CG  . GLN A 1 304 ? 85.242  68.045  107.147 1.00 88.96  ? 304 GLN A CG  1 
ATOM 1337 C CD  . GLN A 1 304 ? 84.258  68.616  108.137 1.00 90.37  ? 304 GLN A CD  1 
ATOM 1338 O OE1 . GLN A 1 304 ? 83.145  68.116  108.277 1.00 94.37  ? 304 GLN A OE1 1 
ATOM 1339 N NE2 . GLN A 1 304 ? 84.664  69.668  108.836 1.00 89.54  ? 304 GLN A NE2 1 
ATOM 1340 N N   . CYS A 1 305 ? 87.272  65.050  106.825 1.00 100.03 ? 305 CYS A N   1 
ATOM 1341 C CA  . CYS A 1 305 ? 88.584  64.840  107.425 1.00 97.49  ? 305 CYS A CA  1 
ATOM 1342 C C   . CYS A 1 305 ? 89.637  64.487  106.383 1.00 98.05  ? 305 CYS A C   1 
ATOM 1343 O O   . CYS A 1 305 ? 90.822  64.775  106.584 1.00 97.54  ? 305 CYS A O   1 
ATOM 1344 C CB  . CYS A 1 305 ? 88.503  63.746  108.488 1.00 97.91  ? 305 CYS A CB  1 
ATOM 1345 S SG  . CYS A 1 305 ? 87.361  64.111  109.842 1.00 100.66 ? 305 CYS A SG  1 
ATOM 1346 N N   . GLN A 1 306 ? 89.234  63.861  105.276 1.00 98.84  ? 306 GLN A N   1 
ATOM 1347 C CA  . GLN A 1 306 ? 90.199  63.509  104.239 1.00 100.59 ? 306 GLN A CA  1 
ATOM 1348 C C   . GLN A 1 306 ? 90.790  64.749  103.581 1.00 97.48  ? 306 GLN A C   1 
ATOM 1349 O O   . GLN A 1 306 ? 91.995  64.796  103.309 1.00 96.99  ? 306 GLN A O   1 
ATOM 1350 C CB  . GLN A 1 306 ? 89.540  62.608  103.196 1.00 100.87 ? 306 GLN A CB  1 
ATOM 1351 C CG  . GLN A 1 306 ? 89.277  61.192  103.678 1.00 100.14 ? 306 GLN A CG  1 
ATOM 1352 C CD  . GLN A 1 306 ? 90.553  60.393  103.853 1.00 98.57  ? 306 GLN A CD  1 
ATOM 1353 O OE1 . GLN A 1 306 ? 91.603  60.754  103.321 1.00 96.22  ? 306 GLN A OE1 1 
ATOM 1354 N NE2 . GLN A 1 306 ? 90.470  59.301  104.601 1.00 100.18 ? 306 GLN A NE2 1 
ATOM 1355 N N   . PHE A 1 307 ? 89.961  65.758  103.307 1.00 87.43  ? 307 PHE A N   1 
ATOM 1356 C CA  . PHE A 1 307 ? 90.471  66.980  102.694 1.00 84.24  ? 307 PHE A CA  1 
ATOM 1357 C C   . PHE A 1 307 ? 91.246  67.823  103.697 1.00 84.01  ? 307 PHE A C   1 
ATOM 1358 O O   . PHE A 1 307 ? 92.285  68.400  103.358 1.00 87.85  ? 307 PHE A O   1 
ATOM 1359 C CB  . PHE A 1 307 ? 89.325  67.785  102.085 1.00 81.25  ? 307 PHE A CB  1 
ATOM 1360 C CG  . PHE A 1 307 ? 88.856  67.259  100.762 1.00 83.38  ? 307 PHE A CG  1 
ATOM 1361 C CD1 . PHE A 1 307 ? 87.870  66.292  100.697 1.00 86.11  ? 307 PHE A CD1 1 
ATOM 1362 C CD2 . PHE A 1 307 ? 89.406  67.728  99.584  1.00 82.38  ? 307 PHE A CD2 1 
ATOM 1363 C CE1 . PHE A 1 307 ? 87.441  65.805  99.481  1.00 84.30  ? 307 PHE A CE1 1 
ATOM 1364 C CE2 . PHE A 1 307 ? 88.980  67.246  98.367  1.00 85.49  ? 307 PHE A CE2 1 
ATOM 1365 C CZ  . PHE A 1 307 ? 87.997  66.282  98.316  1.00 83.58  ? 307 PHE A CZ  1 
ATOM 1366 N N   . GLU A 1 308 ? 90.758  67.907  104.935 1.00 83.69  ? 308 GLU A N   1 
ATOM 1367 C CA  . GLU A 1 308 ? 91.469  68.670  105.954 1.00 83.08  ? 308 GLU A CA  1 
ATOM 1368 C C   . GLU A 1 308 ? 92.807  68.032  106.302 1.00 86.92  ? 308 GLU A C   1 
ATOM 1369 O O   . GLU A 1 308 ? 93.733  68.731  106.726 1.00 88.53  ? 308 GLU A O   1 
ATOM 1370 C CB  . GLU A 1 308 ? 90.601  68.816  107.202 1.00 82.67  ? 308 GLU A CB  1 
ATOM 1371 C CG  . GLU A 1 308 ? 89.338  69.622  106.966 1.00 84.33  ? 308 GLU A CG  1 
ATOM 1372 C CD  . GLU A 1 308 ? 88.537  69.842  108.231 1.00 90.13  ? 308 GLU A CD  1 
ATOM 1373 O OE1 . GLU A 1 308 ? 88.914  69.284  109.282 1.00 90.60  ? 308 GLU A OE1 1 
ATOM 1374 O OE2 . GLU A 1 308 ? 87.531  70.579  108.175 1.00 90.22  ? 308 GLU A OE2 1 
ATOM 1375 N N   . ASP A 1 309 ? 92.929  66.714  106.129 1.00 84.25  ? 309 ASP A N   1 
ATOM 1376 C CA  . ASP A 1 309 ? 94.205  66.047  106.353 1.00 84.69  ? 309 ASP A CA  1 
ATOM 1377 C C   . ASP A 1 309 ? 95.245  66.434  105.311 1.00 82.84  ? 309 ASP A C   1 
ATOM 1378 O O   . ASP A 1 309 ? 96.445  66.334  105.584 1.00 84.54  ? 309 ASP A O   1 
ATOM 1379 C CB  . ASP A 1 309 ? 94.008  64.530  106.358 1.00 88.78  ? 309 ASP A CB  1 
ATOM 1380 C CG  . ASP A 1 309 ? 95.293  63.775  106.628 1.00 91.22  ? 309 ASP A CG  1 
ATOM 1381 O OD1 . ASP A 1 309 ? 95.783  63.822  107.776 1.00 89.44  ? 309 ASP A OD1 1 
ATOM 1382 O OD2 . ASP A 1 309 ? 95.814  63.137  105.690 1.00 87.65  ? 309 ASP A OD2 1 
ATOM 1383 N N   . LEU A 1 310 ? 94.814  66.878  104.129 1.00 81.08  ? 310 LEU A N   1 
ATOM 1384 C CA  . LEU A 1 310 ? 95.745  67.304  103.093 1.00 79.22  ? 310 LEU A CA  1 
ATOM 1385 C C   . LEU A 1 310 ? 96.419  68.628  103.417 1.00 79.17  ? 310 LEU A C   1 
ATOM 1386 O O   . LEU A 1 310 ? 97.370  69.003  102.724 1.00 80.58  ? 310 LEU A O   1 
ATOM 1387 C CB  . LEU A 1 310 ? 95.023  67.408  101.749 1.00 79.00  ? 310 LEU A CB  1 
ATOM 1388 C CG  . LEU A 1 310 ? 94.427  66.106  101.213 1.00 80.79  ? 310 LEU A CG  1 
ATOM 1389 C CD1 . LEU A 1 310 ? 93.724  66.340  99.891  1.00 80.14  ? 310 LEU A CD1 1 
ATOM 1390 C CD2 . LEU A 1 310 ? 95.509  65.053  101.063 1.00 82.75  ? 310 LEU A CD2 1 
ATOM 1391 N N   . ASN A 1 311 ? 95.954  69.341  104.440 1.00 73.98  ? 311 ASN A N   1 
ATOM 1392 C CA  . ASN A 1 311 ? 96.572  70.598  104.844 1.00 72.27  ? 311 ASN A CA  1 
ATOM 1393 C C   . ASN A 1 311 ? 97.972  70.310  105.365 1.00 75.26  ? 311 ASN A C   1 
ATOM 1394 O O   . ASN A 1 311 ? 98.135  69.764  106.460 1.00 79.78  ? 311 ASN A O   1 
ATOM 1395 C CB  . ASN A 1 311 ? 95.719  71.280  105.909 1.00 70.91  ? 311 ASN A CB  1 
ATOM 1396 C CG  . ASN A 1 311 ? 96.106  72.727  106.132 1.00 74.86  ? 311 ASN A CG  1 
ATOM 1397 O OD1 . ASN A 1 311 ? 97.199  73.157  105.766 1.00 76.24  ? 311 ASN A OD1 1 
ATOM 1398 N ND2 . ASN A 1 311 ? 95.210  73.487  106.746 1.00 76.12  ? 311 ASN A ND2 1 
ATOM 1399 N N   . LYS A 1 312 ? 98.985  70.673  104.582 1.00 71.71  ? 312 LYS A N   1 
ATOM 1400 C CA  . LYS A 1 312 ? 100.368 70.410  104.955 1.00 71.80  ? 312 LYS A CA  1 
ATOM 1401 C C   . LYS A 1 312 ? 100.923 71.436  105.931 1.00 74.63  ? 312 LYS A C   1 
ATOM 1402 O O   . LYS A 1 312 ? 101.993 71.206  106.502 1.00 76.59  ? 312 LYS A O   1 
ATOM 1403 C CB  . LYS A 1 312 ? 101.243 70.363  103.702 1.00 75.12  ? 312 LYS A CB  1 
ATOM 1404 C CG  . LYS A 1 312 ? 102.277 69.255  103.712 1.00 75.24  ? 312 LYS A CG  1 
ATOM 1405 C CD  . LYS A 1 312 ? 101.615 67.888  103.773 1.00 75.08  ? 312 LYS A CD  1 
ATOM 1406 C CE  . LYS A 1 312 ? 100.718 67.653  102.569 1.00 77.55  ? 312 LYS A CE  1 
ATOM 1407 N NZ  . LYS A 1 312 ? 100.008 66.346  102.649 1.00 75.39  ? 312 LYS A NZ  1 
ATOM 1408 N N   . ARG A 1 313 ? 100.230 72.554  106.133 1.00 74.44  ? 313 ARG A N   1 
ATOM 1409 C CA  . ARG A 1 313 ? 100.642 73.603  107.065 1.00 72.19  ? 313 ARG A CA  1 
ATOM 1410 C C   . ARG A 1 313 ? 99.430  73.931  107.931 1.00 71.90  ? 313 ARG A C   1 
ATOM 1411 O O   . ARG A 1 313 ? 98.673  74.860  107.640 1.00 74.23  ? 313 ARG A O   1 
ATOM 1412 C CB  . ARG A 1 313 ? 101.171 74.822  106.312 1.00 70.30  ? 313 ARG A CB  1 
ATOM 1413 C CG  . ARG A 1 313 ? 100.358 75.191  105.081 1.00 76.42  ? 313 ARG A CG  1 
ATOM 1414 C CD  . ARG A 1 313 ? 101.214 75.868  104.028 1.00 76.08  ? 313 ARG A CD  1 
ATOM 1415 N NE  . ARG A 1 313 ? 102.181 74.945  103.447 1.00 78.11  ? 313 ARG A NE  1 
ATOM 1416 C CZ  . ARG A 1 313 ? 102.990 75.241  102.440 1.00 76.54  ? 313 ARG A CZ  1 
ATOM 1417 N NH1 . ARG A 1 313 ? 102.979 76.435  101.872 1.00 72.59  ? 313 ARG A NH1 1 
ATOM 1418 N NH2 . ARG A 1 313 ? 103.832 74.315  101.990 1.00 73.69  ? 313 ARG A NH2 1 
ATOM 1419 N N   . LYS A 1 314 ? 99.253  73.170  109.009 1.00 74.28  ? 314 LYS A N   1 
ATOM 1420 C CA  . LYS A 1 314 ? 98.096  73.322  109.878 1.00 77.58  ? 314 LYS A CA  1 
ATOM 1421 C C   . LYS A 1 314 ? 98.278  74.405  110.928 1.00 79.14  ? 314 LYS A C   1 
ATOM 1422 O O   . LYS A 1 314 ? 97.506  74.454  111.892 1.00 82.40  ? 314 LYS A O   1 
ATOM 1423 C CB  . LYS A 1 314 ? 97.768  71.988  110.551 1.00 73.92  ? 314 LYS A CB  1 
ATOM 1424 C CG  . LYS A 1 314 ? 97.337  70.909  109.578 1.00 76.87  ? 314 LYS A CG  1 
ATOM 1425 C CD  . LYS A 1 314 ? 96.868  69.662  110.299 1.00 76.57  ? 314 LYS A CD  1 
ATOM 1426 C CE  . LYS A 1 314 ? 96.372  68.618  109.317 1.00 77.47  ? 314 LYS A CE  1 
ATOM 1427 N NZ  . LYS A 1 314 ? 95.916  67.385  110.012 1.00 79.26  ? 314 LYS A NZ  1 
ATOM 1428 N N   . ASP A 1 315 ? 99.270  75.270  110.765 1.00 76.19  ? 315 ASP A N   1 
ATOM 1429 C CA  . ASP A 1 315 ? 99.511  76.373  111.684 1.00 77.29  ? 315 ASP A CA  1 
ATOM 1430 C C   . ASP A 1 315 ? 99.339  77.734  111.035 1.00 77.85  ? 315 ASP A C   1 
ATOM 1431 O O   . ASP A 1 315 ? 98.754  78.633  111.643 1.00 78.59  ? 315 ASP A O   1 
ATOM 1432 C CB  . ASP A 1 315 ? 100.920 76.264  112.281 1.00 74.64  ? 315 ASP A CB  1 
ATOM 1433 C CG  . ASP A 1 315 ? 101.153 74.941  112.980 1.00 82.66  ? 315 ASP A CG  1 
ATOM 1434 O OD1 . ASP A 1 315 ? 101.268 73.912  112.283 1.00 83.66  ? 315 ASP A OD1 1 
ATOM 1435 O OD2 . ASP A 1 315 ? 101.218 74.929  114.227 1.00 82.53  ? 315 ASP A OD2 1 
ATOM 1436 N N   . THR A 1 316 ? 99.825  77.907  109.806 1.00 69.69  ? 316 THR A N   1 
ATOM 1437 C CA  . THR A 1 316 ? 99.744  79.189  109.120 1.00 71.45  ? 316 THR A CA  1 
ATOM 1438 C C   . THR A 1 316 ? 98.391  79.441  108.468 1.00 74.13  ? 316 THR A C   1 
ATOM 1439 O O   . THR A 1 316 ? 98.139  80.570  108.033 1.00 72.88  ? 316 THR A O   1 
ATOM 1440 C CB  . THR A 1 316 ? 100.841 79.290  108.058 1.00 69.95  ? 316 THR A CB  1 
ATOM 1441 O OG1 . THR A 1 316 ? 100.673 78.245  107.094 1.00 72.28  ? 316 THR A OG1 1 
ATOM 1442 C CG2 . THR A 1 316 ? 102.213 79.165  108.698 1.00 65.96  ? 316 THR A CG2 1 
ATOM 1443 N N   . LYS A 1 317 ? 97.518  78.439  108.388 1.00 69.41  ? 317 LYS A N   1 
ATOM 1444 C CA  . LYS A 1 317 ? 96.227  78.624  107.745 1.00 66.18  ? 317 LYS A CA  1 
ATOM 1445 C C   . LYS A 1 317 ? 95.207  77.691  108.376 1.00 66.76  ? 317 LYS A C   1 
ATOM 1446 O O   . LYS A 1 317 ? 95.557  76.710  109.036 1.00 73.06  ? 317 LYS A O   1 
ATOM 1447 C CB  . LYS A 1 317 ? 96.299  78.363  106.239 1.00 69.17  ? 317 LYS A CB  1 
ATOM 1448 C CG  . LYS A 1 317 ? 96.275  76.893  105.879 1.00 64.29  ? 317 LYS A CG  1 
ATOM 1449 C CD  . LYS A 1 317 ? 96.137  76.694  104.386 1.00 61.56  ? 317 LYS A CD  1 
ATOM 1450 C CE  . LYS A 1 317 ? 97.368  77.172  103.658 1.00 58.22  ? 317 LYS A CE  1 
ATOM 1451 N NZ  . LYS A 1 317 ? 97.210  77.040  102.188 1.00 64.21  ? 317 LYS A NZ  1 
ATOM 1452 N N   . GLU A 1 318 ? 93.935  78.012  108.162 1.00 61.73  ? 318 GLU A N   1 
ATOM 1453 C CA  . GLU A 1 318 ? 92.832  77.173  108.597 1.00 63.18  ? 318 GLU A CA  1 
ATOM 1454 C C   . GLU A 1 318 ? 91.883  76.936  107.433 1.00 67.26  ? 318 GLU A C   1 
ATOM 1455 O O   . GLU A 1 318 ? 91.827  77.715  106.480 1.00 74.79  ? 318 GLU A O   1 
ATOM 1456 C CB  . GLU A 1 318 ? 92.067  77.788  109.776 1.00 67.55  ? 318 GLU A CB  1 
ATOM 1457 C CG  . GLU A 1 318 ? 91.707  79.245  109.603 1.00 66.95  ? 318 GLU A CG  1 
ATOM 1458 C CD  . GLU A 1 318 ? 92.810  80.176  110.057 1.00 75.10  ? 318 GLU A CD  1 
ATOM 1459 O OE1 . GLU A 1 318 ? 93.578  79.791  110.963 1.00 70.48  ? 318 GLU A OE1 1 
ATOM 1460 O OE2 . GLU A 1 318 ? 92.912  81.291  109.506 1.00 76.83  ? 318 GLU A OE2 1 
ATOM 1461 N N   . ILE A 1 319 ? 91.138  75.839  107.521 1.00 63.96  ? 319 ILE A N   1 
ATOM 1462 C CA  . ILE A 1 319 ? 90.210  75.422  106.479 1.00 60.89  ? 319 ILE A CA  1 
ATOM 1463 C C   . ILE A 1 319 ? 88.806  75.466  107.057 1.00 61.68  ? 319 ILE A C   1 
ATOM 1464 O O   . ILE A 1 319 ? 88.512  74.782  108.044 1.00 69.37  ? 319 ILE A O   1 
ATOM 1465 C CB  . ILE A 1 319 ? 90.544  74.019  105.950 1.00 60.42  ? 319 ILE A CB  1 
ATOM 1466 C CG1 . ILE A 1 319 ? 91.958  73.999  105.373 1.00 62.86  ? 319 ILE A CG1 1 
ATOM 1467 C CG2 . ILE A 1 319 ? 89.539  73.591  104.903 1.00 58.80  ? 319 ILE A CG2 1 
ATOM 1468 C CD1 . ILE A 1 319 ? 92.366  72.663  104.829 1.00 64.31  ? 319 ILE A CD1 1 
ATOM 1469 N N   . TYR A 1 320 ? 87.943  76.266  106.447 1.00 51.80  ? 320 TYR A N   1 
ATOM 1470 C CA  . TYR A 1 320 ? 86.549  76.378  106.853 1.00 46.64  ? 320 TYR A CA  1 
ATOM 1471 C C   . TYR A 1 320 ? 85.727  75.472  105.948 1.00 53.15  ? 320 TYR A C   1 
ATOM 1472 O O   . TYR A 1 320 ? 85.560  75.760  104.759 1.00 63.88  ? 320 TYR A O   1 
ATOM 1473 C CB  . TYR A 1 320 ? 86.074  77.825  106.765 1.00 50.70  ? 320 TYR A CB  1 
ATOM 1474 C CG  . TYR A 1 320 ? 86.985  78.812  107.452 1.00 54.63  ? 320 TYR A CG  1 
ATOM 1475 C CD1 . TYR A 1 320 ? 88.039  79.402  106.770 1.00 55.76  ? 320 TYR A CD1 1 
ATOM 1476 C CD2 . TYR A 1 320 ? 86.783  79.167  108.775 1.00 54.20  ? 320 TYR A CD2 1 
ATOM 1477 C CE1 . TYR A 1 320 ? 88.870  80.304  107.387 1.00 53.20  ? 320 TYR A CE1 1 
ATOM 1478 C CE2 . TYR A 1 320 ? 87.612  80.072  109.401 1.00 53.92  ? 320 TYR A CE2 1 
ATOM 1479 C CZ  . TYR A 1 320 ? 88.654  80.636  108.702 1.00 54.59  ? 320 TYR A CZ  1 
ATOM 1480 O OH  . TYR A 1 320 ? 89.481  81.541  109.322 1.00 54.85  ? 320 TYR A OH  1 
ATOM 1481 N N   . THR A 1 321 ? 85.214  74.384  106.508 1.00 61.05  ? 321 THR A N   1 
ATOM 1482 C CA  . THR A 1 321 ? 84.464  73.396  105.747 1.00 63.69  ? 321 THR A CA  1 
ATOM 1483 C C   . THR A 1 321 ? 82.973  73.624  105.943 1.00 62.96  ? 321 THR A C   1 
ATOM 1484 O O   . THR A 1 321 ? 82.507  73.789  107.074 1.00 68.21  ? 321 THR A O   1 
ATOM 1485 C CB  . THR A 1 321 ? 84.841  71.977  106.167 1.00 65.84  ? 321 THR A CB  1 
ATOM 1486 O OG1 . THR A 1 321 ? 86.255  71.798  106.028 1.00 60.86  ? 321 THR A OG1 1 
ATOM 1487 C CG2 . THR A 1 321 ? 84.128  70.965  105.291 1.00 69.13  ? 321 THR A CG2 1 
ATOM 1488 N N   . HIS A 1 322 ? 82.232  73.638  104.839 1.00 60.75  ? 322 HIS A N   1 
ATOM 1489 C CA  . HIS A 1 322 ? 80.793  73.830  104.872 1.00 62.86  ? 322 HIS A CA  1 
ATOM 1490 C C   . HIS A 1 322 ? 80.135  72.820  103.947 1.00 74.22  ? 322 HIS A C   1 
ATOM 1491 O O   . HIS A 1 322 ? 80.729  72.380  102.961 1.00 78.25  ? 322 HIS A O   1 
ATOM 1492 C CB  . HIS A 1 322 ? 80.414  75.256  104.455 1.00 66.01  ? 322 HIS A CB  1 
ATOM 1493 C CG  . HIS A 1 322 ? 78.967  75.585  104.652 1.00 68.07  ? 322 HIS A CG  1 
ATOM 1494 N ND1 . HIS A 1 322 ? 78.357  75.548  105.887 1.00 69.13  ? 322 HIS A ND1 1 
ATOM 1495 C CD2 . HIS A 1 322 ? 78.014  75.970  103.773 1.00 68.27  ? 322 HIS A CD2 1 
ATOM 1496 C CE1 . HIS A 1 322 ? 77.088  75.891  105.759 1.00 70.54  ? 322 HIS A CE1 1 
ATOM 1497 N NE2 . HIS A 1 322 ? 76.854  76.151  104.486 1.00 72.21  ? 322 HIS A NE2 1 
ATOM 1498 N N   . PHE A 1 323 ? 78.904  72.449  104.280 1.00 86.39  ? 323 PHE A N   1 
ATOM 1499 C CA  . PHE A 1 323 ? 78.103  71.536  103.473 1.00 82.50  ? 323 PHE A CA  1 
ATOM 1500 C C   . PHE A 1 323 ? 76.977  72.337  102.834 1.00 84.34  ? 323 PHE A C   1 
ATOM 1501 O O   . PHE A 1 323 ? 76.026  72.733  103.515 1.00 86.66  ? 323 PHE A O   1 
ATOM 1502 C CB  . PHE A 1 323 ? 77.554  70.388  104.316 1.00 82.84  ? 323 PHE A CB  1 
ATOM 1503 C CG  . PHE A 1 323 ? 78.586  69.367  104.699 1.00 84.71  ? 323 PHE A CG  1 
ATOM 1504 C CD1 . PHE A 1 323 ? 79.353  69.529  105.837 1.00 84.38  ? 323 PHE A CD1 1 
ATOM 1505 C CD2 . PHE A 1 323 ? 78.784  68.244  103.920 1.00 84.96  ? 323 PHE A CD2 1 
ATOM 1506 C CE1 . PHE A 1 323 ? 80.299  68.588  106.189 1.00 82.47  ? 323 PHE A CE1 1 
ATOM 1507 C CE2 . PHE A 1 323 ? 79.727  67.302  104.268 1.00 83.58  ? 323 PHE A CE2 1 
ATOM 1508 C CZ  . PHE A 1 323 ? 80.485  67.474  105.404 1.00 80.98  ? 323 PHE A CZ  1 
ATOM 1509 N N   . THR A 1 324 ? 77.085  72.574  101.532 1.00 93.49  ? 324 THR A N   1 
ATOM 1510 C CA  . THR A 1 324 ? 76.086  73.325  100.794 1.00 95.64  ? 324 THR A CA  1 
ATOM 1511 C C   . THR A 1 324 ? 75.098  72.364  100.138 1.00 100.44 ? 324 THR A C   1 
ATOM 1512 O O   . THR A 1 324 ? 75.154  71.147  100.324 1.00 101.09 ? 324 THR A O   1 
ATOM 1513 C CB  . THR A 1 324 ? 76.750  74.227  99.752  1.00 97.37  ? 324 THR A CB  1 
ATOM 1514 O OG1 . THR A 1 324 ? 77.253  73.426  98.678  1.00 97.70  ? 324 THR A OG1 1 
ATOM 1515 C CG2 . THR A 1 324 ? 77.900  74.993  100.372 1.00 97.21  ? 324 THR A CG2 1 
ATOM 1516 N N   . CYS A 1 325 ? 74.181  72.925  99.358  1.00 123.69 ? 325 CYS A N   1 
ATOM 1517 C CA  . CYS A 1 325 ? 73.175  72.139  98.655  1.00 123.25 ? 325 CYS A CA  1 
ATOM 1518 C C   . CYS A 1 325 ? 72.664  72.960  97.478  1.00 123.70 ? 325 CYS A C   1 
ATOM 1519 O O   . CYS A 1 325 ? 73.044  74.119  97.292  1.00 122.98 ? 325 CYS A O   1 
ATOM 1520 C CB  . CYS A 1 325 ? 72.036  71.731  99.594  1.00 123.10 ? 325 CYS A CB  1 
ATOM 1521 S SG  . CYS A 1 325 ? 70.726  70.770  98.804  1.00 128.43 ? 325 CYS A SG  1 
ATOM 1522 N N   . SER A 1 326 ? 71.795  72.343  96.678  1.00 140.97 ? 326 SER A N   1 
ATOM 1523 C CA  . SER A 1 326 ? 71.210  73.033  95.536  1.00 141.34 ? 326 SER A CA  1 
ATOM 1524 C C   . SER A 1 326 ? 70.119  74.013  95.940  1.00 141.07 ? 326 SER A C   1 
ATOM 1525 O O   . SER A 1 326 ? 69.753  74.878  95.137  1.00 140.17 ? 326 SER A O   1 
ATOM 1526 C CB  . SER A 1 326 ? 70.647  72.017  94.539  1.00 140.33 ? 326 SER A CB  1 
ATOM 1527 O OG  . SER A 1 326 ? 71.661  71.142  94.076  1.00 138.98 ? 326 SER A OG  1 
ATOM 1528 N N   . THR A 1 327 ? 69.593  73.901  97.161  1.00 139.42 ? 327 THR A N   1 
ATOM 1529 C CA  . THR A 1 327 ? 68.573  74.815  97.659  1.00 139.35 ? 327 THR A CA  1 
ATOM 1530 C C   . THR A 1 327 ? 69.013  75.537  98.926  1.00 137.67 ? 327 THR A C   1 
ATOM 1531 O O   . THR A 1 327 ? 68.201  76.238  99.542  1.00 137.83 ? 327 THR A O   1 
ATOM 1532 C CB  . THR A 1 327 ? 67.262  74.066  97.919  1.00 140.08 ? 327 THR A CB  1 
ATOM 1533 O OG1 . THR A 1 327 ? 67.485  73.028  98.882  1.00 139.77 ? 327 THR A OG1 1 
ATOM 1534 C CG2 . THR A 1 327 ? 66.732  73.452  96.632  1.00 138.00 ? 327 THR A CG2 1 
ATOM 1535 N N   . ASP A 1 328 ? 70.270  75.385  99.330  1.00 116.54 ? 328 ASP A N   1 
ATOM 1536 C CA  . ASP A 1 328 ? 70.756  76.037  100.536 1.00 117.32 ? 328 ASP A CA  1 
ATOM 1537 C C   . ASP A 1 328 ? 70.897  77.538  100.307 1.00 116.31 ? 328 ASP A C   1 
ATOM 1538 O O   . ASP A 1 328 ? 71.237  77.995  99.212  1.00 114.50 ? 328 ASP A O   1 
ATOM 1539 C CB  . ASP A 1 328 ? 72.095  75.432  100.959 1.00 116.22 ? 328 ASP A CB  1 
ATOM 1540 C CG  . ASP A 1 328 ? 72.490  75.816  102.370 1.00 117.14 ? 328 ASP A CG  1 
ATOM 1541 O OD1 . ASP A 1 328 ? 71.699  76.505  103.047 1.00 117.45 ? 328 ASP A OD1 1 
ATOM 1542 O OD2 . ASP A 1 328 ? 73.591  75.421  102.805 1.00 115.19 ? 328 ASP A OD2 1 
ATOM 1543 N N   . THR A 1 329 ? 70.628  78.311  101.359 1.00 108.70 ? 329 THR A N   1 
ATOM 1544 C CA  . THR A 1 329 ? 70.683  79.764  101.288 1.00 108.87 ? 329 THR A CA  1 
ATOM 1545 C C   . THR A 1 329 ? 71.615  80.388  102.316 1.00 109.73 ? 329 THR A C   1 
ATOM 1546 O O   . THR A 1 329 ? 71.691  81.621  102.392 1.00 106.82 ? 329 THR A O   1 
ATOM 1547 C CB  . THR A 1 329 ? 69.278  80.359  101.453 1.00 108.85 ? 329 THR A CB  1 
ATOM 1548 O OG1 . THR A 1 329 ? 69.357  81.790  101.432 1.00 109.20 ? 329 THR A OG1 1 
ATOM 1549 C CG2 . THR A 1 329 ? 68.659  79.908  102.766 1.00 107.42 ? 329 THR A CG2 1 
ATOM 1550 N N   . LYS A 1 330 ? 72.323  79.585  103.107 1.00 94.09  ? 330 LYS A N   1 
ATOM 1551 C CA  . LYS A 1 330 ? 73.234  80.087  104.124 1.00 88.38  ? 330 LYS A CA  1 
ATOM 1552 C C   . LYS A 1 330 ? 74.686  80.070  103.670 1.00 89.23  ? 330 LYS A C   1 
ATOM 1553 O O   . LYS A 1 330 ? 75.582  80.307  104.485 1.00 89.82  ? 330 LYS A O   1 
ATOM 1554 C CB  . LYS A 1 330 ? 73.081  79.273  105.409 1.00 87.56  ? 330 LYS A CB  1 
ATOM 1555 C CG  . LYS A 1 330 ? 71.666  79.248  105.957 1.00 90.80  ? 330 LYS A CG  1 
ATOM 1556 C CD  . LYS A 1 330 ? 71.566  78.375  107.195 1.00 90.41  ? 330 LYS A CD  1 
ATOM 1557 C CE  . LYS A 1 330 ? 70.143  78.338  107.728 1.00 90.43  ? 330 LYS A CE  1 
ATOM 1558 N NZ  . LYS A 1 330 ? 70.024  77.471  108.933 1.00 90.08  ? 330 LYS A NZ  1 
ATOM 1559 N N   . ASN A 1 331 ? 74.939  79.784  102.391 1.00 84.73  ? 331 ASN A N   1 
ATOM 1560 C CA  . ASN A 1 331 ? 76.311  79.739  101.898 1.00 79.85  ? 331 ASN A CA  1 
ATOM 1561 C C   . ASN A 1 331 ? 76.974  81.107  101.968 1.00 79.37  ? 331 ASN A C   1 
ATOM 1562 O O   . ASN A 1 331 ? 78.145  81.217  102.349 1.00 79.91  ? 331 ASN A O   1 
ATOM 1563 C CB  . ASN A 1 331 ? 76.335  79.207  100.467 1.00 81.38  ? 331 ASN A CB  1 
ATOM 1564 C CG  . ASN A 1 331 ? 75.696  77.844  100.346 1.00 85.50  ? 331 ASN A CG  1 
ATOM 1565 O OD1 . ASN A 1 331 ? 75.607  77.101  101.322 1.00 89.51  ? 331 ASN A OD1 1 
ATOM 1566 N ND2 . ASN A 1 331 ? 75.244  77.506  99.145  1.00 85.48  ? 331 ASN A ND2 1 
ATOM 1567 N N   . VAL A 1 332 ? 76.245  82.160  101.599 1.00 71.81  ? 332 VAL A N   1 
ATOM 1568 C CA  . VAL A 1 332 ? 76.813  83.503  101.650 1.00 74.28  ? 332 VAL A CA  1 
ATOM 1569 C C   . VAL A 1 332 ? 77.067  83.925  103.093 1.00 76.39  ? 332 VAL A C   1 
ATOM 1570 O O   . VAL A 1 332 ? 78.053  84.609  103.387 1.00 77.19  ? 332 VAL A O   1 
ATOM 1571 C CB  . VAL A 1 332 ? 75.901  84.498  100.908 1.00 71.24  ? 332 VAL A CB  1 
ATOM 1572 C CG1 . VAL A 1 332 ? 74.505  84.504  101.507 1.00 72.92  ? 332 VAL A CG1 1 
ATOM 1573 C CG2 . VAL A 1 332 ? 76.505  85.891  100.923 1.00 71.31  ? 332 VAL A CG2 1 
ATOM 1574 N N   . GLN A 1 333 ? 76.191  83.521  104.017 1.00 63.98  ? 333 GLN A N   1 
ATOM 1575 C CA  . GLN A 1 333 ? 76.420  83.825  105.426 1.00 63.12  ? 333 GLN A CA  1 
ATOM 1576 C C   . GLN A 1 333 ? 77.664  83.117  105.945 1.00 65.97  ? 333 GLN A C   1 
ATOM 1577 O O   . GLN A 1 333 ? 78.421  83.684  106.741 1.00 66.03  ? 333 GLN A O   1 
ATOM 1578 C CB  . GLN A 1 333 ? 75.199  83.440  106.257 1.00 64.30  ? 333 GLN A CB  1 
ATOM 1579 C CG  . GLN A 1 333 ? 75.362  83.704  107.744 1.00 63.02  ? 333 GLN A CG  1 
ATOM 1580 C CD  . GLN A 1 333 ? 75.518  85.177  108.062 1.00 67.45  ? 333 GLN A CD  1 
ATOM 1581 O OE1 . GLN A 1 333 ? 74.989  86.035  107.357 1.00 69.80  ? 333 GLN A OE1 1 
ATOM 1582 N NE2 . GLN A 1 333 ? 76.250  85.479  109.126 1.00 65.39  ? 333 GLN A NE2 1 
ATOM 1583 N N   . PHE A 1 334 ? 77.884  81.872  105.518 1.00 62.03  ? 334 PHE A N   1 
ATOM 1584 C CA  . PHE A 1 334 ? 79.083  81.152  105.930 1.00 57.78  ? 334 PHE A CA  1 
ATOM 1585 C C   . PHE A 1 334 ? 80.342  81.841  105.422 1.00 55.98  ? 334 PHE A C   1 
ATOM 1586 O O   . PHE A 1 334 ? 81.342  81.932  106.142 1.00 64.20  ? 334 PHE A O   1 
ATOM 1587 C CB  . PHE A 1 334 ? 79.029  79.709  105.433 1.00 56.75  ? 334 PHE A CB  1 
ATOM 1588 C CG  . PHE A 1 334 ? 80.212  78.887  105.841 1.00 50.01  ? 334 PHE A CG  1 
ATOM 1589 C CD1 . PHE A 1 334 ? 80.209  78.195  107.035 1.00 58.81  ? 334 PHE A CD1 1 
ATOM 1590 C CD2 . PHE A 1 334 ? 81.330  78.811  105.034 1.00 49.16  ? 334 PHE A CD2 1 
ATOM 1591 C CE1 . PHE A 1 334 ? 81.295  77.441  107.414 1.00 60.32  ? 334 PHE A CE1 1 
ATOM 1592 C CE2 . PHE A 1 334 ? 82.418  78.065  105.411 1.00 55.82  ? 334 PHE A CE2 1 
ATOM 1593 C CZ  . PHE A 1 334 ? 82.401  77.378  106.603 1.00 60.03  ? 334 PHE A CZ  1 
ATOM 1594 N N   . VAL A 1 335 ? 80.319  82.315  104.176 1.00 54.58  ? 335 VAL A N   1 
ATOM 1595 C CA  . VAL A 1 335 ? 81.485  82.996  103.624 1.00 56.73  ? 335 VAL A CA  1 
ATOM 1596 C C   . VAL A 1 335 ? 81.759  84.277  104.395 1.00 61.77  ? 335 VAL A C   1 
ATOM 1597 O O   . VAL A 1 335 ? 82.914  84.607  104.689 1.00 65.43  ? 335 VAL A O   1 
ATOM 1598 C CB  . VAL A 1 335 ? 81.293  83.261  102.120 1.00 56.22  ? 335 VAL A CB  1 
ATOM 1599 C CG1 . VAL A 1 335 ? 82.421  84.117  101.584 1.00 57.48  ? 335 VAL A CG1 1 
ATOM 1600 C CG2 . VAL A 1 335 ? 81.234  81.950  101.369 1.00 58.32  ? 335 VAL A CG2 1 
ATOM 1601 N N   . PHE A 1 336 ? 80.706  85.017  104.739 1.00 57.17  ? 336 PHE A N   1 
ATOM 1602 C CA  . PHE A 1 336 ? 80.894  86.243  105.503 1.00 51.17  ? 336 PHE A CA  1 
ATOM 1603 C C   . PHE A 1 336 ? 81.518  85.953  106.861 1.00 53.37  ? 336 PHE A C   1 
ATOM 1604 O O   . PHE A 1 336 ? 82.438  86.656  107.291 1.00 63.55  ? 336 PHE A O   1 
ATOM 1605 C CB  . PHE A 1 336 ? 79.561  86.969  105.668 1.00 54.95  ? 336 PHE A CB  1 
ATOM 1606 C CG  . PHE A 1 336 ? 79.637  88.171  106.557 1.00 59.15  ? 336 PHE A CG  1 
ATOM 1607 C CD1 . PHE A 1 336 ? 80.161  89.361  106.090 1.00 57.65  ? 336 PHE A CD1 1 
ATOM 1608 C CD2 . PHE A 1 336 ? 79.181  88.112  107.861 1.00 58.41  ? 336 PHE A CD2 1 
ATOM 1609 C CE1 . PHE A 1 336 ? 80.235  90.466  106.906 1.00 58.60  ? 336 PHE A CE1 1 
ATOM 1610 C CE2 . PHE A 1 336 ? 79.251  89.213  108.681 1.00 57.75  ? 336 PHE A CE2 1 
ATOM 1611 C CZ  . PHE A 1 336 ? 79.779  90.393  108.203 1.00 60.37  ? 336 PHE A CZ  1 
ATOM 1612 N N   . ASP A 1 337 ? 81.033  84.919  107.551 1.00 61.30  ? 337 ASP A N   1 
ATOM 1613 C CA  . ASP A 1 337 ? 81.631  84.542  108.828 1.00 56.74  ? 337 ASP A CA  1 
ATOM 1614 C C   . ASP A 1 337 ? 83.056  84.040  108.646 1.00 53.51  ? 337 ASP A C   1 
ATOM 1615 O O   . ASP A 1 337 ? 83.944  84.382  109.434 1.00 66.25  ? 337 ASP A O   1 
ATOM 1616 C CB  . ASP A 1 337 ? 80.778  83.481  109.516 1.00 60.81  ? 337 ASP A CB  1 
ATOM 1617 C CG  . ASP A 1 337 ? 79.365  83.946  109.774 1.00 64.91  ? 337 ASP A CG  1 
ATOM 1618 O OD1 . ASP A 1 337 ? 79.024  85.072  109.358 1.00 65.49  ? 337 ASP A OD1 1 
ATOM 1619 O OD2 . ASP A 1 337 ? 78.595  83.189  110.399 1.00 61.98  ? 337 ASP A OD2 1 
ATOM 1620 N N   . ALA A 1 338 ? 83.294  83.219  107.622 1.00 48.07  ? 338 ALA A N   1 
ATOM 1621 C CA  . ALA A 1 338 ? 84.640  82.711  107.382 1.00 45.73  ? 338 ALA A CA  1 
ATOM 1622 C C   . ALA A 1 338 ? 85.598  83.834  107.006 1.00 50.14  ? 338 ALA A C   1 
ATOM 1623 O O   . ALA A 1 338 ? 86.748  83.849  107.452 1.00 53.72  ? 338 ALA A O   1 
ATOM 1624 C CB  . ALA A 1 338 ? 84.610  81.640  106.294 1.00 48.19  ? 338 ALA A CB  1 
ATOM 1625 N N   . VAL A 1 339 ? 85.144  84.777  106.179 1.00 54.19  ? 339 VAL A N   1 
ATOM 1626 C CA  . VAL A 1 339 ? 85.986  85.909  105.804 1.00 46.71  ? 339 VAL A CA  1 
ATOM 1627 C C   . VAL A 1 339 ? 86.223  86.821  107.000 1.00 47.75  ? 339 VAL A C   1 
ATOM 1628 O O   . VAL A 1 339 ? 87.318  87.368  107.172 1.00 50.65  ? 339 VAL A O   1 
ATOM 1629 C CB  . VAL A 1 339 ? 85.358  86.667  104.622 1.00 45.63  ? 339 VAL A CB  1 
ATOM 1630 C CG1 . VAL A 1 339 ? 85.978  88.035  104.475 1.00 52.31  ? 339 VAL A CG1 1 
ATOM 1631 C CG2 . VAL A 1 339 ? 85.538  85.873  103.345 1.00 49.35  ? 339 VAL A CG2 1 
ATOM 1632 N N   . THR A 1 340 ? 85.205  86.994  107.848 1.00 56.54  ? 340 THR A N   1 
ATOM 1633 C CA  . THR A 1 340 ? 85.354  87.838  109.029 1.00 47.72  ? 340 THR A CA  1 
ATOM 1634 C C   . THR A 1 340 ? 86.468  87.328  109.932 1.00 49.15  ? 340 THR A C   1 
ATOM 1635 O O   . THR A 1 340 ? 87.265  88.116  110.453 1.00 57.28  ? 340 THR A O   1 
ATOM 1636 C CB  . THR A 1 340 ? 84.035  87.903  109.794 1.00 44.00  ? 340 THR A CB  1 
ATOM 1637 O OG1 . THR A 1 340 ? 83.006  88.382  108.923 1.00 55.39  ? 340 THR A OG1 1 
ATOM 1638 C CG2 . THR A 1 340 ? 84.153  88.834  110.983 1.00 45.86  ? 340 THR A CG2 1 
ATOM 1639 N N   . ASP A 1 341 ? 86.542  86.011  110.125 1.00 54.76  ? 341 ASP A N   1 
ATOM 1640 C CA  . ASP A 1 341 ? 87.638  85.436  110.895 1.00 49.45  ? 341 ASP A CA  1 
ATOM 1641 C C   . ASP A 1 341 ? 88.976  85.658  110.201 1.00 48.07  ? 341 ASP A C   1 
ATOM 1642 O O   . ASP A 1 341 ? 89.998  85.865  110.863 1.00 59.48  ? 341 ASP A O   1 
ATOM 1643 C CB  . ASP A 1 341 ? 87.388  83.947  111.122 1.00 53.17  ? 341 ASP A CB  1 
ATOM 1644 C CG  . ASP A 1 341 ? 88.467  83.299  111.959 1.00 64.39  ? 341 ASP A CG  1 
ATOM 1645 O OD1 . ASP A 1 341 ? 88.507  83.554  113.180 1.00 67.52  ? 341 ASP A OD1 1 
ATOM 1646 O OD2 . ASP A 1 341 ? 89.277  82.536  111.395 1.00 63.30  ? 341 ASP A OD2 1 
ATOM 1647 N N   . VAL A 1 342 ? 88.992  85.608  108.868 1.00 47.47  ? 342 VAL A N   1 
ATOM 1648 C CA  . VAL A 1 342 ? 90.222  85.869  108.128 1.00 43.64  ? 342 VAL A CA  1 
ATOM 1649 C C   . VAL A 1 342 ? 90.625  87.332  108.254 1.00 46.29  ? 342 VAL A C   1 
ATOM 1650 O O   . VAL A 1 342 ? 91.815  87.657  108.338 1.00 53.70  ? 342 VAL A O   1 
ATOM 1651 C CB  . VAL A 1 342 ? 90.058  85.451  106.656 1.00 46.74  ? 342 VAL A CB  1 
ATOM 1652 C CG1 . VAL A 1 342 ? 91.298  85.799  105.864 1.00 45.23  ? 342 VAL A CG1 1 
ATOM 1653 C CG2 . VAL A 1 342 ? 89.786  83.967  106.560 1.00 49.37  ? 342 VAL A CG2 1 
ATOM 1654 N N   . ILE A 1 343 ? 89.647  88.240  108.253 1.00 52.34  ? 343 ILE A N   1 
ATOM 1655 C CA  . ILE A 1 343 ? 89.946  89.658  108.431 1.00 47.36  ? 343 ILE A CA  1 
ATOM 1656 C C   . ILE A 1 343 ? 90.525  89.914  109.817 1.00 48.23  ? 343 ILE A C   1 
ATOM 1657 O O   . ILE A 1 343 ? 91.506  90.651  109.969 1.00 52.79  ? 343 ILE A O   1 
ATOM 1658 C CB  . ILE A 1 343 ? 88.685  90.504  108.176 1.00 44.59  ? 343 ILE A CB  1 
ATOM 1659 C CG1 . ILE A 1 343 ? 88.260  90.394  106.714 1.00 43.99  ? 343 ILE A CG1 1 
ATOM 1660 C CG2 . ILE A 1 343 ? 88.927  91.953  108.546 1.00 43.75  ? 343 ILE A CG2 1 
ATOM 1661 C CD1 . ILE A 1 343 ? 87.003  91.150  106.394 1.00 42.84  ? 343 ILE A CD1 1 
ATOM 1662 N N   . ILE A 1 344 ? 89.935  89.302  110.846 1.00 49.30  ? 344 ILE A N   1 
ATOM 1663 C CA  . ILE A 1 344 ? 90.449  89.455  112.205 1.00 34.78  ? 344 ILE A CA  1 
ATOM 1664 C C   . ILE A 1 344 ? 91.878  88.945  112.299 1.00 35.76  ? 344 ILE A C   1 
ATOM 1665 O O   . ILE A 1 344 ? 92.738  89.579  112.918 1.00 55.37  ? 344 ILE A O   1 
ATOM 1666 C CB  . ILE A 1 344 ? 89.530  88.737  113.210 1.00 41.38  ? 344 ILE A CB  1 
ATOM 1667 C CG1 . ILE A 1 344 ? 88.161  89.408  113.259 1.00 39.79  ? 344 ILE A CG1 1 
ATOM 1668 C CG2 . ILE A 1 344 ? 90.162  88.711  114.587 1.00 50.79  ? 344 ILE A CG2 1 
ATOM 1669 C CD1 . ILE A 1 344 ? 87.206  88.765  114.227 1.00 39.74  ? 344 ILE A CD1 1 
ATOM 1670 N N   . LYS A 1 345 ? 92.157  87.798  111.679 1.00 41.77  ? 345 LYS A N   1 
ATOM 1671 C CA  . LYS A 1 345 ? 93.500  87.232  111.740 1.00 41.51  ? 345 LYS A CA  1 
ATOM 1672 C C   . LYS A 1 345 ? 94.523  88.160  111.101 1.00 46.81  ? 345 LYS A C   1 
ATOM 1673 O O   . LYS A 1 345 ? 95.631  88.325  111.621 1.00 55.24  ? 345 LYS A O   1 
ATOM 1674 C CB  . LYS A 1 345 ? 93.521  85.865  111.062 1.00 39.03  ? 345 LYS A CB  1 
ATOM 1675 C CG  . LYS A 1 345 ? 94.834  85.130  111.194 1.00 46.85  ? 345 LYS A CG  1 
ATOM 1676 C CD  . LYS A 1 345 ? 94.783  83.800  110.468 1.00 55.46  ? 345 LYS A CD  1 
ATOM 1677 C CE  . LYS A 1 345 ? 96.094  83.052  110.593 1.00 56.25  ? 345 LYS A CE  1 
ATOM 1678 N NZ  . LYS A 1 345 ? 96.055  81.748  109.879 1.00 55.13  ? 345 LYS A NZ  1 
ATOM 1679 N N   . ASN A 1 346 ? 94.174  88.771  109.968 1.00 49.83  ? 346 ASN A N   1 
ATOM 1680 C CA  . ASN A 1 346 ? 95.094  89.697  109.317 1.00 45.38  ? 346 ASN A CA  1 
ATOM 1681 C C   . ASN A 1 346 ? 95.291  90.959  110.147 1.00 48.47  ? 346 ASN A C   1 
ATOM 1682 O O   . ASN A 1 346 ? 96.397  91.508  110.195 1.00 54.72  ? 346 ASN A O   1 
ATOM 1683 C CB  . ASN A 1 346 ? 94.585  90.047  107.921 1.00 50.45  ? 346 ASN A CB  1 
ATOM 1684 C CG  . ASN A 1 346 ? 94.472  88.835  107.023 1.00 56.89  ? 346 ASN A CG  1 
ATOM 1685 O OD1 . ASN A 1 346 ? 95.239  87.882  107.149 1.00 49.48  ? 346 ASN A OD1 1 
ATOM 1686 N ND2 . ASN A 1 346 ? 93.512  88.865  106.109 1.00 60.33  ? 346 ASN A ND2 1 
ATOM 1687 N N   . ASN A 1 347 ? 94.230  91.440  110.799 1.00 51.11  ? 347 ASN A N   1 
ATOM 1688 C CA  . ASN A 1 347 ? 94.358  92.612  111.659 1.00 44.70  ? 347 ASN A CA  1 
ATOM 1689 C C   . ASN A 1 347 ? 95.289  92.336  112.831 1.00 47.14  ? 347 ASN A C   1 
ATOM 1690 O O   . ASN A 1 347 ? 96.091  93.196  113.211 1.00 58.28  ? 347 ASN A O   1 
ATOM 1691 C CB  . ASN A 1 347 ? 92.985  93.048  112.165 1.00 43.01  ? 347 ASN A CB  1 
ATOM 1692 C CG  . ASN A 1 347 ? 92.087  93.544  111.058 1.00 42.80  ? 347 ASN A CG  1 
ATOM 1693 O OD1 . ASN A 1 347 ? 92.386  93.369  109.880 1.00 51.20  ? 347 ASN A OD1 1 
ATOM 1694 N ND2 . ASN A 1 347 ? 90.973  94.160  111.429 1.00 45.49  ? 347 ASN A ND2 1 
ATOM 1695 N N   . LEU A 1 348 ? 95.193  91.143  113.420 1.00 47.82  ? 348 LEU A N   1 
ATOM 1696 C CA  . LEU A 1 348 ? 96.052  90.800  114.549 1.00 44.78  ? 348 LEU A CA  1 
ATOM 1697 C C   . LEU A 1 348 ? 97.519  90.769  114.143 1.00 48.78  ? 348 LEU A C   1 
ATOM 1698 O O   . LEU A 1 348 ? 98.391  91.182  114.915 1.00 64.15  ? 348 LEU A O   1 
ATOM 1699 C CB  . LEU A 1 348 ? 95.634  89.454  115.138 1.00 48.98  ? 348 LEU A CB  1 
ATOM 1700 C CG  . LEU A 1 348 ? 94.239  89.371  115.757 1.00 49.72  ? 348 LEU A CG  1 
ATOM 1701 C CD1 . LEU A 1 348 ? 93.956  87.963  116.241 1.00 49.12  ? 348 LEU A CD1 1 
ATOM 1702 C CD2 . LEU A 1 348 ? 94.101  90.361  116.891 1.00 48.71  ? 348 LEU A CD2 1 
ATOM 1703 N N   . LYS A 1 349 ? 97.816  90.265  112.945 1.00 48.40  ? 349 LYS A N   1 
ATOM 1704 C CA  . LYS A 1 349 ? 99.201  90.213  112.486 1.00 51.87  ? 349 LYS A CA  1 
ATOM 1705 C C   . LYS A 1 349 ? 99.774  91.611  112.293 1.00 61.12  ? 349 LYS A C   1 
ATOM 1706 O O   . LYS A 1 349 ? 100.902 91.893  112.712 1.00 65.14  ? 349 LYS A O   1 
ATOM 1707 C CB  . LYS A 1 349 ? 99.296  89.415  111.187 1.00 56.35  ? 349 LYS A CB  1 
ATOM 1708 C CG  . LYS A 1 349 ? 98.833  87.977  111.298 1.00 61.31  ? 349 LYS A CG  1 
ATOM 1709 C CD  . LYS A 1 349 ? 98.850  87.302  109.938 1.00 59.60  ? 349 LYS A CD  1 
ATOM 1710 C CE  . LYS A 1 349 ? 98.291  85.894  110.012 1.00 58.72  ? 349 LYS A CE  1 
ATOM 1711 N NZ  . LYS A 1 349 ? 98.201  85.265  108.667 1.00 59.81  ? 349 LYS A NZ  1 
ATOM 1712 N N   . ASP A 1 350 ? 99.013  92.499  111.651 1.00 66.92  ? 350 ASP A N   1 
ATOM 1713 C CA  . ASP A 1 350 ? 99.501  93.853  111.406 1.00 63.80  ? 350 ASP A CA  1 
ATOM 1714 C C   . ASP A 1 350 ? 99.654  94.634  112.704 1.00 67.92  ? 350 ASP A C   1 
ATOM 1715 O O   . ASP A 1 350 ? 100.624 95.380  112.874 1.00 71.63  ? 350 ASP A O   1 
ATOM 1716 C CB  . ASP A 1 350 ? 98.565  94.585  110.447 1.00 61.14  ? 350 ASP A CB  1 
ATOM 1717 C CG  . ASP A 1 350 ? 98.548  93.965  109.066 1.00 74.89  ? 350 ASP A CG  1 
ATOM 1718 O OD1 . ASP A 1 350 ? 99.564  93.351  108.677 1.00 70.56  ? 350 ASP A OD1 1 
ATOM 1719 O OD2 . ASP A 1 350 ? 97.522  94.095  108.366 1.00 80.07  ? 350 ASP A OD2 1 
ATOM 1720 N N   . CYS A 1 351 ? 98.708  94.479  113.631 1.00 56.61  ? 351 CYS A N   1 
ATOM 1721 C CA  . CYS A 1 351 ? 98.777  95.192  114.899 1.00 55.71  ? 351 CYS A CA  1 
ATOM 1722 C C   . CYS A 1 351 ? 99.885  94.678  115.804 1.00 59.06  ? 351 CYS A C   1 
ATOM 1723 O O   . CYS A 1 351 ? 100.190 95.327  116.809 1.00 64.46  ? 351 CYS A O   1 
ATOM 1724 C CB  . CYS A 1 351 ? 97.434  95.108  115.622 1.00 53.57  ? 351 CYS A CB  1 
ATOM 1725 S SG  . CYS A 1 351 ? 96.094  95.977  114.788 1.00 65.67  ? 351 CYS A SG  1 
ATOM 1726 N N   . GLY A 1 352 ? 100.494 93.541  115.478 1.00 55.84  ? 352 GLY A N   1 
ATOM 1727 C CA  . GLY A 1 352 ? 101.569 92.988  116.267 1.00 60.19  ? 352 GLY A CA  1 
ATOM 1728 C C   . GLY A 1 352 ? 101.152 91.991  117.324 1.00 60.36  ? 352 GLY A C   1 
ATOM 1729 O O   . GLY A 1 352 ? 102.027 91.369  117.939 1.00 63.74  ? 352 GLY A O   1 
ATOM 1730 N N   . LEU A 1 353 ? 99.850  91.817  117.561 1.00 49.47  ? 353 LEU A N   1 
ATOM 1731 C CA  . LEU A 1 353 ? 99.407  90.820  118.531 1.00 55.86  ? 353 LEU A CA  1 
ATOM 1732 C C   . LEU A 1 353 ? 99.754  89.409  118.075 1.00 57.30  ? 353 LEU A C   1 
ATOM 1733 O O   . LEU A 1 353 ? 100.176 88.575  118.883 1.00 59.98  ? 353 LEU A O   1 
ATOM 1734 C CB  . LEU A 1 353 ? 97.905  90.951  118.769 1.00 53.93  ? 353 LEU A CB  1 
ATOM 1735 C CG  . LEU A 1 353 ? 97.455  92.191  119.533 1.00 52.95  ? 353 LEU A CG  1 
ATOM 1736 C CD1 . LEU A 1 353 ? 95.947  92.251  119.605 1.00 54.50  ? 353 LEU A CD1 1 
ATOM 1737 C CD2 . LEU A 1 353 ? 98.049  92.178  120.924 1.00 57.13  ? 353 LEU A CD2 1 
ATOM 1738 N N   . PHE A 1 354 ? 99.585  89.124  116.790 1.00 73.33  ? 354 PHE A N   1 
ATOM 1739 C CA  . PHE A 1 354 ? 99.868  87.800  116.254 1.00 75.89  ? 354 PHE A CA  1 
ATOM 1740 C C   . PHE A 1 354 ? 101.290 87.741  115.703 1.00 77.62  ? 354 PHE A C   1 
ATOM 1741 O O   . PHE A 1 354 ? 101.720 88.623  114.961 1.00 78.80  ? 354 PHE A O   1 
ATOM 1742 C CB  . PHE A 1 354 ? 98.853  87.447  115.165 1.00 72.28  ? 354 PHE A CB  1 
ATOM 1743 C CG  . PHE A 1 354 ? 98.587  85.977  115.031 1.00 68.45  ? 354 PHE A CG  1 
ATOM 1744 C CD1 . PHE A 1 354 ? 99.511  85.044  115.460 1.00 74.74  ? 354 PHE A CD1 1 
ATOM 1745 C CD2 . PHE A 1 354 ? 97.400  85.531  114.479 1.00 73.98  ? 354 PHE A CD2 1 
ATOM 1746 C CE1 . PHE A 1 354 ? 99.262  83.693  115.335 1.00 78.91  ? 354 PHE A CE1 1 
ATOM 1747 C CE2 . PHE A 1 354 ? 97.143  84.182  114.353 1.00 75.38  ? 354 PHE A CE2 1 
ATOM 1748 C CZ  . PHE A 1 354 ? 98.075  83.262  114.781 1.00 75.59  ? 354 PHE A CZ  1 
ATOM 1749 O OXT . PHE A 1 354 ? 102.041 86.808  115.982 1.00 76.10  ? 354 PHE A OXT 1 
ATOM 1750 N N   . SER B 2 12  ? 99.692  52.848  60.381  1.00 157.80 ? 2   SER B N   1 
ATOM 1751 C CA  . SER B 2 12  ? 100.557 52.653  59.224  1.00 158.38 ? 2   SER B CA  1 
ATOM 1752 C C   . SER B 2 12  ? 101.047 53.989  58.676  1.00 159.00 ? 2   SER B C   1 
ATOM 1753 O O   . SER B 2 12  ? 102.234 54.305  58.758  1.00 157.84 ? 2   SER B O   1 
ATOM 1754 C CB  . SER B 2 12  ? 99.824  51.873  58.131  1.00 157.56 ? 2   SER B CB  1 
ATOM 1755 O OG  . SER B 2 12  ? 98.665  52.566  57.700  1.00 157.15 ? 2   SER B OG  1 
ATOM 1756 N N   . GLU B 2 13  ? 100.122 54.768  58.110  1.00 159.68 ? 3   GLU B N   1 
ATOM 1757 C CA  . GLU B 2 13  ? 100.486 56.075  57.572  1.00 158.43 ? 3   GLU B CA  1 
ATOM 1758 C C   . GLU B 2 13  ? 100.950 57.017  58.675  1.00 158.97 ? 3   GLU B C   1 
ATOM 1759 O O   . GLU B 2 13  ? 101.919 57.765  58.497  1.00 158.65 ? 3   GLU B O   1 
ATOM 1760 C CB  . GLU B 2 13  ? 99.305  56.677  56.811  1.00 157.09 ? 3   GLU B CB  1 
ATOM 1761 C CG  . GLU B 2 13  ? 99.613  57.998  56.126  1.00 158.11 ? 3   GLU B CG  1 
ATOM 1762 C CD  . GLU B 2 13  ? 100.587 57.849  54.973  1.00 158.77 ? 3   GLU B CD  1 
ATOM 1763 O OE1 . GLU B 2 13  ? 100.700 56.732  54.425  1.00 158.26 ? 3   GLU B OE1 1 
ATOM 1764 O OE2 . GLU B 2 13  ? 101.241 58.850  54.614  1.00 159.01 ? 3   GLU B OE2 1 
ATOM 1765 N N   . LEU B 2 14  ? 100.266 57.000  59.822  1.00 159.58 ? 4   LEU B N   1 
ATOM 1766 C CA  . LEU B 2 14  ? 100.666 57.855  60.935  1.00 159.51 ? 4   LEU B CA  1 
ATOM 1767 C C   . LEU B 2 14  ? 102.039 57.463  61.464  1.00 159.75 ? 4   LEU B C   1 
ATOM 1768 O O   . LEU B 2 14  ? 102.869 58.330  61.764  1.00 158.96 ? 4   LEU B O   1 
ATOM 1769 C CB  . LEU B 2 14  ? 99.623  57.790  62.049  1.00 159.95 ? 4   LEU B CB  1 
ATOM 1770 C CG  . LEU B 2 14  ? 99.938  58.603  63.306  1.00 159.46 ? 4   LEU B CG  1 
ATOM 1771 C CD1 . LEU B 2 14  ? 100.083 60.077  62.967  1.00 159.13 ? 4   LEU B CD1 1 
ATOM 1772 C CD2 . LEU B 2 14  ? 98.867  58.396  64.365  1.00 158.88 ? 4   LEU B CD2 1 
ATOM 1773 N N   . ASP B 2 15  ? 102.293 56.159  61.594  1.00 161.16 ? 5   ASP B N   1 
ATOM 1774 C CA  . ASP B 2 15  ? 103.594 55.698  62.069  1.00 161.38 ? 5   ASP B CA  1 
ATOM 1775 C C   . ASP B 2 15  ? 104.707 56.097  61.109  1.00 160.59 ? 5   ASP B C   1 
ATOM 1776 O O   . ASP B 2 15  ? 105.794 56.498  61.538  1.00 159.71 ? 5   ASP B O   1 
ATOM 1777 C CB  . ASP B 2 15  ? 103.572 54.183  62.267  1.00 161.52 ? 5   ASP B CB  1 
ATOM 1778 C CG  . ASP B 2 15  ? 102.501 53.738  63.243  1.00 161.44 ? 5   ASP B CG  1 
ATOM 1779 O OD1 . ASP B 2 15  ? 101.767 54.607  63.757  1.00 162.01 ? 5   ASP B OD1 1 
ATOM 1780 O OD2 . ASP B 2 15  ? 102.394 52.520  63.496  1.00 160.65 ? 5   ASP B OD2 1 
ATOM 1781 N N   . GLN B 2 16  ? 104.457 55.983  59.802  1.00 160.85 ? 6   GLN B N   1 
ATOM 1782 C CA  . GLN B 2 16  ? 105.468 56.361  58.820  1.00 160.97 ? 6   GLN B CA  1 
ATOM 1783 C C   . GLN B 2 16  ? 105.772 57.853  58.883  1.00 160.74 ? 6   GLN B C   1 
ATOM 1784 O O   . GLN B 2 16  ? 106.935 58.261  58.781  1.00 159.53 ? 6   GLN B O   1 
ATOM 1785 C CB  . GLN B 2 16  ? 105.008 55.958  57.418  1.00 160.63 ? 6   GLN B CB  1 
ATOM 1786 C CG  . GLN B 2 16  ? 106.039 56.184  56.320  1.00 160.64 ? 6   GLN B CG  1 
ATOM 1787 C CD  . GLN B 2 16  ? 105.946 57.565  55.699  1.00 160.43 ? 6   GLN B CD  1 
ATOM 1788 O OE1 . GLN B 2 16  ? 104.987 58.301  55.932  1.00 160.57 ? 6   GLN B OE1 1 
ATOM 1789 N NE2 . GLN B 2 16  ? 106.946 57.924  54.903  1.00 159.26 ? 6   GLN B NE2 1 
ATOM 1790 N N   . LEU B 2 17  ? 104.739 58.685  59.043  1.00 158.41 ? 7   LEU B N   1 
ATOM 1791 C CA  . LEU B 2 17  ? 104.952 60.129  59.062  1.00 157.59 ? 7   LEU B CA  1 
ATOM 1792 C C   . LEU B 2 17  ? 105.759 60.565  60.279  1.00 157.38 ? 7   LEU B C   1 
ATOM 1793 O O   . LEU B 2 17  ? 106.668 61.394  60.160  1.00 157.39 ? 7   LEU B O   1 
ATOM 1794 C CB  . LEU B 2 17  ? 103.612 60.861  59.019  1.00 156.80 ? 7   LEU B CB  1 
ATOM 1795 C CG  . LEU B 2 17  ? 102.896 60.860  57.668  1.00 157.16 ? 7   LEU B CG  1 
ATOM 1796 C CD1 . LEU B 2 17  ? 101.636 61.700  57.738  1.00 156.97 ? 7   LEU B CD1 1 
ATOM 1797 C CD2 . LEU B 2 17  ? 103.819 61.367  56.573  1.00 156.61 ? 7   LEU B CD2 1 
ATOM 1798 N N   . ARG B 2 18  ? 105.445 60.022  61.459  1.00 158.71 ? 8   ARG B N   1 
ATOM 1799 C CA  . ARG B 2 18  ? 106.183 60.410  62.655  1.00 158.64 ? 8   ARG B CA  1 
ATOM 1800 C C   . ARG B 2 18  ? 107.625 59.923  62.627  1.00 159.18 ? 8   ARG B C   1 
ATOM 1801 O O   . ARG B 2 18  ? 108.468 60.484  63.335  1.00 158.21 ? 8   ARG B O   1 
ATOM 1802 C CB  . ARG B 2 18  ? 105.479 59.895  63.912  1.00 157.61 ? 8   ARG B CB  1 
ATOM 1803 C CG  . ARG B 2 18  ? 105.535 58.390  64.101  1.00 158.31 ? 8   ARG B CG  1 
ATOM 1804 C CD  . ARG B 2 18  ? 105.079 58.002  65.499  1.00 158.24 ? 8   ARG B CD  1 
ATOM 1805 N NE  . ARG B 2 18  ? 105.133 56.561  65.716  1.00 159.16 ? 8   ARG B NE  1 
ATOM 1806 C CZ  . ARG B 2 18  ? 104.087 55.750  65.624  1.00 159.22 ? 8   ARG B CZ  1 
ATOM 1807 N NH1 . ARG B 2 18  ? 102.882 56.208  65.326  1.00 158.74 ? 8   ARG B NH1 1 
ATOM 1808 N NH2 . ARG B 2 18  ? 104.255 54.449  65.839  1.00 158.45 ? 8   ARG B NH2 1 
ATOM 1809 N N   . GLN B 2 19  ? 107.928 58.895  61.831  1.00 160.12 ? 9   GLN B N   1 
ATOM 1810 C CA  . GLN B 2 19  ? 109.321 58.507  61.637  1.00 159.36 ? 9   GLN B CA  1 
ATOM 1811 C C   . GLN B 2 19  ? 110.051 59.512  60.756  1.00 158.77 ? 9   GLN B C   1 
ATOM 1812 O O   . GLN B 2 19  ? 111.240 59.780  60.964  1.00 158.31 ? 9   GLN B O   1 
ATOM 1813 C CB  . GLN B 2 19  ? 109.400 57.104  61.035  1.00 159.85 ? 9   GLN B CB  1 
ATOM 1814 C CG  . GLN B 2 19  ? 108.955 56.000  61.978  1.00 159.33 ? 9   GLN B CG  1 
ATOM 1815 C CD  . GLN B 2 19  ? 109.062 54.623  61.354  1.00 159.23 ? 9   GLN B CD  1 
ATOM 1816 O OE1 . GLN B 2 19  ? 109.451 54.483  60.194  1.00 158.77 ? 9   GLN B OE1 1 
ATOM 1817 N NE2 . GLN B 2 19  ? 108.717 53.596  62.122  1.00 158.94 ? 9   GLN B NE2 1 
ATOM 1818 N N   . GLU B 2 20  ? 109.356 60.078  59.765  1.00 154.71 ? 10  GLU B N   1 
ATOM 1819 C CA  . GLU B 2 20  ? 109.973 61.086  58.911  1.00 154.56 ? 10  GLU B CA  1 
ATOM 1820 C C   . GLU B 2 20  ? 110.286 62.360  59.685  1.00 154.71 ? 10  GLU B C   1 
ATOM 1821 O O   . GLU B 2 20  ? 111.278 63.035  59.388  1.00 154.00 ? 10  GLU B O   1 
ATOM 1822 C CB  . GLU B 2 20  ? 109.067 61.394  57.718  1.00 154.33 ? 10  GLU B CB  1 
ATOM 1823 C CG  . GLU B 2 20  ? 109.688 62.329  56.694  1.00 154.37 ? 10  GLU B CG  1 
ATOM 1824 C CD  . GLU B 2 20  ? 108.799 62.545  55.486  1.00 154.90 ? 10  GLU B CD  1 
ATOM 1825 O OE1 . GLU B 2 20  ? 107.697 61.958  55.445  1.00 155.64 ? 10  GLU B OE1 1 
ATOM 1826 O OE2 . GLU B 2 20  ? 109.204 63.298  54.576  1.00 153.49 ? 10  GLU B OE2 1 
ATOM 1827 N N   . ALA B 2 21  ? 109.455 62.704  60.672  1.00 157.04 ? 11  ALA B N   1 
ATOM 1828 C CA  . ALA B 2 21  ? 109.739 63.868  61.504  1.00 155.83 ? 11  ALA B CA  1 
ATOM 1829 C C   . ALA B 2 21  ? 111.036 63.683  62.279  1.00 156.57 ? 11  ALA B C   1 
ATOM 1830 O O   . ALA B 2 21  ? 111.831 64.621  62.409  1.00 158.39 ? 11  ALA B O   1 
ATOM 1831 C CB  . ALA B 2 21  ? 108.574 64.132  62.457  1.00 155.72 ? 11  ALA B CB  1 
ATOM 1832 N N   . GLU B 2 22  ? 111.264 62.479  62.809  1.00 149.16 ? 12  GLU B N   1 
ATOM 1833 C CA  . GLU B 2 22  ? 112.513 62.203  63.512  1.00 149.42 ? 12  GLU B CA  1 
ATOM 1834 C C   . GLU B 2 22  ? 113.708 62.315  62.573  1.00 149.13 ? 12  GLU B C   1 
ATOM 1835 O O   . GLU B 2 22  ? 114.766 62.823  62.961  1.00 147.97 ? 12  GLU B O   1 
ATOM 1836 C CB  . GLU B 2 22  ? 112.460 60.817  64.154  1.00 149.02 ? 12  GLU B CB  1 
ATOM 1837 C CG  . GLU B 2 22  ? 111.384 60.666  65.217  1.00 149.29 ? 12  GLU B CG  1 
ATOM 1838 C CD  . GLU B 2 22  ? 111.669 61.485  66.461  1.00 149.69 ? 12  GLU B CD  1 
ATOM 1839 O OE1 . GLU B 2 22  ? 112.848 61.822  66.698  1.00 149.16 ? 12  GLU B OE1 1 
ATOM 1840 O OE2 . GLU B 2 22  ? 110.713 61.792  67.203  1.00 149.90 ? 12  GLU B OE2 1 
ATOM 1841 N N   . GLN B 2 23  ? 113.559 61.837  61.335  1.00 147.96 ? 13  GLN B N   1 
ATOM 1842 C CA  . GLN B 2 23  ? 114.631 61.976  60.355  1.00 147.34 ? 13  GLN B CA  1 
ATOM 1843 C C   . GLN B 2 23  ? 114.906 63.442  60.045  1.00 147.60 ? 13  GLN B C   1 
ATOM 1844 O O   . GLN B 2 23  ? 116.065 63.847  59.898  1.00 147.43 ? 13  GLN B O   1 
ATOM 1845 C CB  . GLN B 2 23  ? 114.276 61.215  59.078  1.00 147.23 ? 13  GLN B CB  1 
ATOM 1846 C CG  . GLN B 2 23  ? 114.075 59.724  59.281  1.00 147.92 ? 13  GLN B CG  1 
ATOM 1847 C CD  . GLN B 2 23  ? 113.702 59.007  57.999  1.00 147.99 ? 13  GLN B CD  1 
ATOM 1848 O OE1 . GLN B 2 23  ? 113.593 59.623  56.939  1.00 148.01 ? 13  GLN B OE1 1 
ATOM 1849 N NE2 . GLN B 2 23  ? 113.503 57.697  58.090  1.00 147.32 ? 13  GLN B NE2 1 
ATOM 1850 N N   . LEU B 2 24  ? 113.851 64.252  59.935  1.00 142.24 ? 14  LEU B N   1 
ATOM 1851 C CA  . LEU B 2 24  ? 114.038 65.678  59.688  1.00 140.32 ? 14  LEU B CA  1 
ATOM 1852 C C   . LEU B 2 24  ? 114.703 66.361  60.876  1.00 140.59 ? 14  LEU B C   1 
ATOM 1853 O O   . LEU B 2 24  ? 115.551 67.242  60.696  1.00 142.90 ? 14  LEU B O   1 
ATOM 1854 C CB  . LEU B 2 24  ? 112.698 66.337  59.366  1.00 140.77 ? 14  LEU B CB  1 
ATOM 1855 C CG  . LEU B 2 24  ? 112.080 65.952  58.021  1.00 141.60 ? 14  LEU B CG  1 
ATOM 1856 C CD1 . LEU B 2 24  ? 110.699 66.560  57.868  1.00 141.14 ? 14  LEU B CD1 1 
ATOM 1857 C CD2 . LEU B 2 24  ? 112.982 66.390  56.882  1.00 140.86 ? 14  LEU B CD2 1 
ATOM 1858 N N   . LYS B 2 25  ? 114.328 65.974  62.098  1.00 139.41 ? 15  LYS B N   1 
ATOM 1859 C CA  . LYS B 2 25  ? 114.970 66.541  63.279  1.00 140.27 ? 15  LYS B CA  1 
ATOM 1860 C C   . LYS B 2 25  ? 116.451 66.185  63.329  1.00 141.05 ? 15  LYS B C   1 
ATOM 1861 O O   . LYS B 2 25  ? 117.286 67.025  63.684  1.00 140.38 ? 15  LYS B O   1 
ATOM 1862 C CB  . LYS B 2 25  ? 114.262 66.066  64.547  1.00 139.79 ? 15  LYS B CB  1 
ATOM 1863 C CG  . LYS B 2 25  ? 112.871 66.646  64.736  1.00 139.98 ? 15  LYS B CG  1 
ATOM 1864 C CD  . LYS B 2 25  ? 112.267 66.201  66.056  1.00 140.76 ? 15  LYS B CD  1 
ATOM 1865 C CE  . LYS B 2 25  ? 110.896 66.815  66.270  1.00 140.74 ? 15  LYS B CE  1 
ATOM 1866 N NZ  . LYS B 2 25  ? 110.301 66.399  67.570  1.00 140.58 ? 15  LYS B NZ  1 
ATOM 1867 N N   . ASN B 2 26  ? 116.796 64.942  62.984  1.00 141.47 ? 16  ASN B N   1 
ATOM 1868 C CA  . ASN B 2 26  ? 118.204 64.562  62.927  1.00 139.97 ? 16  ASN B CA  1 
ATOM 1869 C C   . ASN B 2 26  ? 118.933 65.313  61.821  1.00 138.00 ? 16  ASN B C   1 
ATOM 1870 O O   . ASN B 2 26  ? 120.109 65.664  61.973  1.00 137.77 ? 16  ASN B O   1 
ATOM 1871 C CB  . ASN B 2 26  ? 118.335 63.052  62.730  1.00 139.74 ? 16  ASN B CB  1 
ATOM 1872 C CG  . ASN B 2 26  ? 117.777 62.263  63.895  1.00 140.37 ? 16  ASN B CG  1 
ATOM 1873 O OD1 . ASN B 2 26  ? 117.774 62.733  65.033  1.00 139.49 ? 16  ASN B OD1 1 
ATOM 1874 N ND2 . ASN B 2 26  ? 117.301 61.055  63.619  1.00 139.37 ? 16  ASN B ND2 1 
ATOM 1875 N N   . GLN B 2 27  ? 118.256 65.560  60.697  1.00 130.54 ? 17  GLN B N   1 
ATOM 1876 C CA  . GLN B 2 27  ? 118.872 66.322  59.617  1.00 130.40 ? 17  GLN B CA  1 
ATOM 1877 C C   . GLN B 2 27  ? 119.185 67.744  60.060  1.00 129.97 ? 17  GLN B C   1 
ATOM 1878 O O   . GLN B 2 27  ? 120.252 68.283  59.741  1.00 130.52 ? 17  GLN B O   1 
ATOM 1879 C CB  . GLN B 2 27  ? 117.963 66.328  58.389  1.00 130.20 ? 17  GLN B CB  1 
ATOM 1880 C CG  . GLN B 2 27  ? 118.526 67.101  57.209  1.00 129.45 ? 17  GLN B CG  1 
ATOM 1881 C CD  . GLN B 2 27  ? 117.614 67.063  56.000  1.00 130.86 ? 17  GLN B CD  1 
ATOM 1882 O OE1 . GLN B 2 27  ? 116.573 66.407  56.013  1.00 132.12 ? 17  GLN B OE1 1 
ATOM 1883 N NE2 . GLN B 2 27  ? 118.002 67.769  54.944  1.00 129.64 ? 17  GLN B NE2 1 
ATOM 1884 N N   . ILE B 2 28  ? 118.262 68.371  60.792  1.00 124.26 ? 18  ILE B N   1 
ATOM 1885 C CA  . ILE B 2 28  ? 118.499 69.722  61.288  1.00 123.22 ? 18  ILE B CA  1 
ATOM 1886 C C   . ILE B 2 28  ? 119.630 69.726  62.308  1.00 123.50 ? 18  ILE B C   1 
ATOM 1887 O O   . ILE B 2 28  ? 120.500 70.605  62.286  1.00 124.70 ? 18  ILE B O   1 
ATOM 1888 C CB  . ILE B 2 28  ? 117.203 70.309  61.876  1.00 123.54 ? 18  ILE B CB  1 
ATOM 1889 C CG1 . ILE B 2 28  ? 116.123 70.403  60.799  1.00 123.23 ? 18  ILE B CG1 1 
ATOM 1890 C CG2 . ILE B 2 28  ? 117.462 71.674  62.483  1.00 124.34 ? 18  ILE B CG2 1 
ATOM 1891 C CD1 . ILE B 2 28  ? 114.814 70.971  61.296  1.00 122.67 ? 18  ILE B CD1 1 
ATOM 1892 N N   . ARG B 2 29  ? 119.638 68.748  63.216  1.00 122.07 ? 19  ARG B N   1 
ATOM 1893 C CA  . ARG B 2 29  ? 120.683 68.689  64.233  1.00 121.44 ? 19  ARG B CA  1 
ATOM 1894 C C   . ARG B 2 29  ? 122.056 68.486  63.606  1.00 121.32 ? 19  ARG B C   1 
ATOM 1895 O O   . ARG B 2 29  ? 123.040 69.097  64.039  1.00 121.78 ? 19  ARG B O   1 
ATOM 1896 C CB  . ARG B 2 29  ? 120.378 67.573  65.231  1.00 123.30 ? 19  ARG B CB  1 
ATOM 1897 C CG  . ARG B 2 29  ? 121.456 67.361  66.278  1.00 121.83 ? 19  ARG B CG  1 
ATOM 1898 C CD  . ARG B 2 29  ? 121.038 66.306  67.287  1.00 123.14 ? 19  ARG B CD  1 
ATOM 1899 N NE  . ARG B 2 29  ? 120.610 65.072  66.637  1.00 125.71 ? 19  ARG B NE  1 
ATOM 1900 C CZ  . ARG B 2 29  ? 121.424 64.082  66.299  1.00 125.22 ? 19  ARG B CZ  1 
ATOM 1901 N NH1 . ARG B 2 29  ? 122.725 64.146  66.531  1.00 125.37 ? 19  ARG B NH1 1 
ATOM 1902 N NH2 . ARG B 2 29  ? 120.921 63.001  65.710  1.00 121.73 ? 19  ARG B NH2 1 
ATOM 1903 N N   . ASP B 2 30  ? 122.143 67.631  62.584  1.00 123.48 ? 20  ASP B N   1 
ATOM 1904 C CA  . ASP B 2 30  ? 123.406 67.451  61.875  1.00 122.62 ? 20  ASP B CA  1 
ATOM 1905 C C   . ASP B 2 30  ? 123.816 68.720  61.136  1.00 123.28 ? 20  ASP B C   1 
ATOM 1906 O O   . ASP B 2 30  ? 125.005 69.053  61.078  1.00 122.62 ? 20  ASP B O   1 
ATOM 1907 C CB  . ASP B 2 30  ? 123.301 66.276  60.906  1.00 123.89 ? 20  ASP B CB  1 
ATOM 1908 C CG  . ASP B 2 30  ? 123.120 64.951  61.617  1.00 126.11 ? 20  ASP B CG  1 
ATOM 1909 O OD1 . ASP B 2 30  ? 123.644 64.804  62.741  1.00 124.40 ? 20  ASP B OD1 1 
ATOM 1910 O OD2 . ASP B 2 30  ? 122.455 64.058  61.053  1.00 126.02 ? 20  ASP B OD2 1 
ATOM 1911 N N   . ALA B 2 31  ? 122.848 69.431  60.553  1.00 117.19 ? 21  ALA B N   1 
ATOM 1912 C CA  . ALA B 2 31  ? 123.167 70.665  59.844  1.00 114.16 ? 21  ALA B CA  1 
ATOM 1913 C C   . ALA B 2 31  ? 123.710 71.725  60.793  1.00 113.94 ? 21  ALA B C   1 
ATOM 1914 O O   . ALA B 2 31  ? 124.664 72.437  60.461  1.00 113.83 ? 21  ALA B O   1 
ATOM 1915 C CB  . ALA B 2 31  ? 121.932 71.185  59.109  1.00 113.18 ? 21  ALA B CB  1 
ATOM 1916 N N   . ARG B 2 32  ? 123.111 71.847  61.980  1.00 100.98 ? 22  ARG B N   1 
ATOM 1917 C CA  . ARG B 2 32  ? 123.608 72.803  62.964  1.00 96.81  ? 22  ARG B CA  1 
ATOM 1918 C C   . ARG B 2 32  ? 124.992 72.414  63.468  1.00 97.35  ? 22  ARG B C   1 
ATOM 1919 O O   . ARG B 2 32  ? 125.854 73.280  63.660  1.00 100.12 ? 22  ARG B O   1 
ATOM 1920 C CB  . ARG B 2 32  ? 122.621 72.916  64.124  1.00 93.16  ? 22  ARG B CB  1 
ATOM 1921 C CG  . ARG B 2 32  ? 121.268 73.468  63.713  1.00 94.74  ? 22  ARG B CG  1 
ATOM 1922 C CD  . ARG B 2 32  ? 120.278 73.448  64.860  1.00 94.32  ? 22  ARG B CD  1 
ATOM 1923 N NE  . ARG B 2 32  ? 119.042 74.135  64.506  1.00 95.69  ? 22  ARG B NE  1 
ATOM 1924 C CZ  . ARG B 2 32  ? 118.032 74.342  65.338  1.00 96.01  ? 22  ARG B CZ  1 
ATOM 1925 N NH1 . ARG B 2 32  ? 118.072 73.919  66.591  1.00 96.44  ? 22  ARG B NH1 1 
ATOM 1926 N NH2 . ARG B 2 32  ? 116.958 74.994  64.906  1.00 92.43  ? 22  ARG B NH2 1 
ATOM 1927 N N   . LYS B 2 33  ? 125.223 71.120  63.693  1.00 108.92 ? 23  LYS B N   1 
ATOM 1928 C CA  . LYS B 2 33  ? 126.535 70.664  64.140  1.00 108.65 ? 23  LYS B CA  1 
ATOM 1929 C C   . LYS B 2 33  ? 127.604 70.879  63.075  1.00 110.03 ? 23  LYS B C   1 
ATOM 1930 O O   . LYS B 2 33  ? 128.774 71.098  63.409  1.00 109.20 ? 23  LYS B O   1 
ATOM 1931 C CB  . LYS B 2 33  ? 126.468 69.191  64.541  1.00 109.14 ? 23  LYS B CB  1 
ATOM 1932 C CG  . LYS B 2 33  ? 127.755 68.648  65.137  1.00 110.71 ? 23  LYS B CG  1 
ATOM 1933 C CD  . LYS B 2 33  ? 127.593 67.205  65.582  1.00 111.91 ? 23  LYS B CD  1 
ATOM 1934 C CE  . LYS B 2 33  ? 126.544 67.081  66.673  1.00 111.39 ? 23  LYS B CE  1 
ATOM 1935 N NZ  . LYS B 2 33  ? 126.899 67.886  67.874  1.00 108.63 ? 23  LYS B NZ  1 
ATOM 1936 N N   . ALA B 2 34  ? 127.225 70.820  61.796  1.00 107.33 ? 24  ALA B N   1 
ATOM 1937 C CA  . ALA B 2 34  ? 128.196 71.005  60.722  1.00 106.63 ? 24  ALA B CA  1 
ATOM 1938 C C   . ALA B 2 34  ? 128.801 72.404  60.738  1.00 105.40 ? 24  ALA B C   1 
ATOM 1939 O O   . ALA B 2 34  ? 130.004 72.569  60.511  1.00 107.48 ? 24  ALA B O   1 
ATOM 1940 C CB  . ALA B 2 34  ? 127.540 70.725  59.371  1.00 105.57 ? 24  ALA B CB  1 
ATOM 1941 N N   . CYS B 2 35  ? 127.988 73.422  61.002  1.00 97.90  ? 25  CYS B N   1 
ATOM 1942 C CA  . CYS B 2 35  ? 128.455 74.802  61.000  1.00 97.06  ? 25  CYS B CA  1 
ATOM 1943 C C   . CYS B 2 35  ? 128.972 75.264  62.355  1.00 98.03  ? 25  CYS B C   1 
ATOM 1944 O O   . CYS B 2 35  ? 129.353 76.431  62.489  1.00 99.61  ? 25  CYS B O   1 
ATOM 1945 C CB  . CYS B 2 35  ? 127.334 75.736  60.533  1.00 96.85  ? 25  CYS B CB  1 
ATOM 1946 S SG  . CYS B 2 35  ? 125.863 75.724  61.580  1.00 103.97 ? 25  CYS B SG  1 
ATOM 1947 N N   . ALA B 2 36  ? 129.014 74.383  63.352  1.00 98.58  ? 26  ALA B N   1 
ATOM 1948 C CA  . ALA B 2 36  ? 129.536 74.724  64.675  1.00 97.73  ? 26  ALA B CA  1 
ATOM 1949 C C   . ALA B 2 36  ? 131.053 74.531  64.729  1.00 99.60  ? 26  ALA B C   1 
ATOM 1950 O O   . ALA B 2 36  ? 131.592 73.776  65.537  1.00 99.70  ? 26  ALA B O   1 
ATOM 1951 C CB  . ALA B 2 36  ? 128.833 73.899  65.746  1.00 95.91  ? 26  ALA B CB  1 
ATOM 1952 N N   . ASP B 2 37  ? 131.743 75.238  63.831  1.00 99.32  ? 27  ASP B N   1 
ATOM 1953 C CA  . ASP B 2 37  ? 133.196 75.115  63.753  1.00 99.55  ? 27  ASP B CA  1 
ATOM 1954 C C   . ASP B 2 37  ? 133.866 75.630  65.021  1.00 100.36 ? 27  ASP B C   1 
ATOM 1955 O O   . ASP B 2 37  ? 134.832 75.029  65.506  1.00 99.92  ? 27  ASP B O   1 
ATOM 1956 C CB  . ASP B 2 37  ? 133.725 75.859  62.525  1.00 99.38  ? 27  ASP B CB  1 
ATOM 1957 C CG  . ASP B 2 37  ? 133.303 77.314  62.497  1.00 101.22 ? 27  ASP B CG  1 
ATOM 1958 O OD1 . ASP B 2 37  ? 132.479 77.712  63.346  1.00 101.96 ? 27  ASP B OD1 1 
ATOM 1959 O OD2 . ASP B 2 37  ? 133.795 78.062  61.626  1.00 100.20 ? 27  ASP B OD2 1 
ATOM 1960 N N   . ALA B 2 38  ? 133.374 76.737  65.570  1.00 97.70  ? 28  ALA B N   1 
ATOM 1961 C CA  . ALA B 2 38  ? 133.965 77.354  66.747  1.00 97.09  ? 28  ALA B CA  1 
ATOM 1962 C C   . ALA B 2 38  ? 132.874 77.636  67.773  1.00 95.11  ? 28  ALA B C   1 
ATOM 1963 O O   . ALA B 2 38  ? 131.687 77.397  67.537  1.00 94.13  ? 28  ALA B O   1 
ATOM 1964 C CB  . ALA B 2 38  ? 134.715 78.641  66.380  1.00 95.23  ? 28  ALA B CB  1 
ATOM 1965 N N   . THR B 2 39  ? 133.293 78.147  68.926  1.00 88.81  ? 29  THR B N   1 
ATOM 1966 C CA  . THR B 2 39  ? 132.394 78.536  70.000  1.00 91.22  ? 29  THR B CA  1 
ATOM 1967 C C   . THR B 2 39  ? 132.501 80.037  70.224  1.00 92.98  ? 29  THR B C   1 
ATOM 1968 O O   . THR B 2 39  ? 133.573 80.627  70.058  1.00 91.43  ? 29  THR B O   1 
ATOM 1969 C CB  . THR B 2 39  ? 132.719 77.785  71.297  1.00 89.92  ? 29  THR B CB  1 
ATOM 1970 O OG1 . THR B 2 39  ? 132.904 76.394  71.009  1.00 91.31  ? 29  THR B OG1 1 
ATOM 1971 C CG2 . THR B 2 39  ? 131.585 77.930  72.298  1.00 88.46  ? 29  THR B CG2 1 
ATOM 1972 N N   . LEU B 2 40  ? 131.376 80.656  70.595  1.00 79.31  ? 30  LEU B N   1 
ATOM 1973 C CA  . LEU B 2 40  ? 131.395 82.078  70.927  1.00 74.83  ? 30  LEU B CA  1 
ATOM 1974 C C   . LEU B 2 40  ? 132.387 82.368  72.045  1.00 77.77  ? 30  LEU B C   1 
ATOM 1975 O O   . LEU B 2 40  ? 133.034 83.421  72.053  1.00 76.92  ? 30  LEU B O   1 
ATOM 1976 C CB  . LEU B 2 40  ? 129.993 82.545  71.321  1.00 72.36  ? 30  LEU B CB  1 
ATOM 1977 C CG  . LEU B 2 40  ? 129.845 84.018  71.710  1.00 70.87  ? 30  LEU B CG  1 
ATOM 1978 C CD1 . LEU B 2 40  ? 130.270 84.923  70.571  1.00 73.61  ? 30  LEU B CD1 1 
ATOM 1979 C CD2 . LEU B 2 40  ? 128.423 84.329  72.136  1.00 69.36  ? 30  LEU B CD2 1 
ATOM 1980 N N   . SER B 2 41  ? 132.527 81.440  72.995  1.00 84.92  ? 31  SER B N   1 
ATOM 1981 C CA  . SER B 2 41  ? 133.510 81.610  74.058  1.00 83.47  ? 31  SER B CA  1 
ATOM 1982 C C   . SER B 2 41  ? 134.926 81.658  73.501  1.00 84.44  ? 31  SER B C   1 
ATOM 1983 O O   . SER B 2 41  ? 135.741 82.484  73.929  1.00 86.67  ? 31  SER B O   1 
ATOM 1984 C CB  . SER B 2 41  ? 133.375 80.485  75.082  1.00 82.95  ? 31  SER B CB  1 
ATOM 1985 O OG  . SER B 2 41  ? 134.341 80.614  76.110  1.00 83.73  ? 31  SER B OG  1 
ATOM 1986 N N   . GLN B 2 42  ? 135.242 80.777  72.550  1.00 83.61  ? 32  GLN B N   1 
ATOM 1987 C CA  . GLN B 2 42  ? 136.568 80.793  71.940  1.00 86.91  ? 32  GLN B CA  1 
ATOM 1988 C C   . GLN B 2 42  ? 136.798 82.072  71.144  1.00 87.23  ? 32  GLN B C   1 
ATOM 1989 O O   . GLN B 2 42  ? 137.902 82.627  71.157  1.00 87.59  ? 32  GLN B O   1 
ATOM 1990 C CB  . GLN B 2 42  ? 136.748 79.565  71.048  1.00 86.78  ? 32  GLN B CB  1 
ATOM 1991 C CG  . GLN B 2 42  ? 136.481 78.248  71.755  1.00 89.49  ? 32  GLN B CG  1 
ATOM 1992 C CD  . GLN B 2 42  ? 136.603 77.054  70.830  1.00 91.98  ? 32  GLN B CD  1 
ATOM 1993 O OE1 . GLN B 2 42  ? 137.049 77.181  69.690  1.00 89.67  ? 32  GLN B OE1 1 
ATOM 1994 N NE2 . GLN B 2 42  ? 136.203 75.886  71.317  1.00 88.94  ? 32  GLN B NE2 1 
ATOM 1995 N N   . ILE B 2 43  ? 135.769 82.551  70.442  1.00 82.49  ? 33  ILE B N   1 
ATOM 1996 C CA  . ILE B 2 43  ? 135.918 83.747  69.619  1.00 81.34  ? 33  ILE B CA  1 
ATOM 1997 C C   . ILE B 2 43  ? 136.182 84.967  70.494  1.00 82.82  ? 33  ILE B C   1 
ATOM 1998 O O   . ILE B 2 43  ? 137.020 85.815  70.164  1.00 85.11  ? 33  ILE B O   1 
ATOM 1999 C CB  . ILE B 2 43  ? 134.677 83.943  68.730  1.00 84.51  ? 33  ILE B CB  1 
ATOM 2000 C CG1 . ILE B 2 43  ? 134.471 82.732  67.819  1.00 82.91  ? 33  ILE B CG1 1 
ATOM 2001 C CG2 . ILE B 2 43  ? 134.821 85.196  67.888  1.00 83.70  ? 33  ILE B CG2 1 
ATOM 2002 C CD1 . ILE B 2 43  ? 135.618 82.475  66.875  1.00 81.85  ? 33  ILE B CD1 1 
ATOM 2003 N N   . THR B 2 44  ? 135.478 85.075  71.621  1.00 82.03  ? 34  THR B N   1 
ATOM 2004 C CA  . THR B 2 44  ? 135.555 86.239  72.493  1.00 79.73  ? 34  THR B CA  1 
ATOM 2005 C C   . THR B 2 44  ? 136.514 86.029  73.660  1.00 77.60  ? 34  THR B C   1 
ATOM 2006 O O   . THR B 2 44  ? 136.434 86.752  74.657  1.00 81.11  ? 34  THR B O   1 
ATOM 2007 C CB  . THR B 2 44  ? 134.167 86.600  73.024  1.00 76.71  ? 34  THR B CB  1 
ATOM 2008 O OG1 . THR B 2 44  ? 133.690 85.547  73.867  1.00 81.16  ? 34  THR B OG1 1 
ATOM 2009 C CG2 . THR B 2 44  ? 133.196 86.789  71.877  1.00 79.17  ? 34  THR B CG2 1 
ATOM 2010 N N   . ASN B 2 45  ? 137.409 85.046  73.563  1.00 84.42  ? 35  ASN B N   1 
ATOM 2011 C CA  . ASN B 2 45  ? 138.374 84.822  74.633  1.00 88.94  ? 35  ASN B CA  1 
ATOM 2012 C C   . ASN B 2 45  ? 139.392 85.954  74.709  1.00 89.31  ? 35  ASN B C   1 
ATOM 2013 O O   . ASN B 2 45  ? 139.815 86.345  75.804  1.00 86.68  ? 35  ASN B O   1 
ATOM 2014 C CB  . ASN B 2 45  ? 139.077 83.481  74.427  1.00 88.00  ? 35  ASN B CB  1 
ATOM 2015 C CG  . ASN B 2 45  ? 140.031 83.144  75.552  1.00 88.43  ? 35  ASN B CG  1 
ATOM 2016 O OD1 . ASN B 2 45  ? 139.862 83.601  76.682  1.00 87.70  ? 35  ASN B OD1 1 
ATOM 2017 N ND2 . ASN B 2 45  ? 141.042 82.340  75.248  1.00 87.05  ? 35  ASN B ND2 1 
ATOM 2018 N N   . ASN B 2 46  ? 139.801 86.490  73.558  1.00 93.18  ? 36  ASN B N   1 
ATOM 2019 C CA  . ASN B 2 46  ? 140.853 87.501  73.538  1.00 92.09  ? 36  ASN B CA  1 
ATOM 2020 C C   . ASN B 2 46  ? 140.383 88.844  74.086  1.00 91.36  ? 36  ASN B C   1 
ATOM 2021 O O   . ASN B 2 46  ? 141.176 89.564  74.704  1.00 90.63  ? 36  ASN B O   1 
ATOM 2022 C CB  . ASN B 2 46  ? 141.387 87.672  72.117  1.00 92.32  ? 36  ASN B CB  1 
ATOM 2023 C CG  . ASN B 2 46  ? 142.040 86.413  71.587  1.00 94.42  ? 36  ASN B CG  1 
ATOM 2024 O OD1 . ASN B 2 46  ? 141.820 85.319  72.107  1.00 95.10  ? 36  ASN B OD1 1 
ATOM 2025 N ND2 . ASN B 2 46  ? 142.851 86.560  70.545  1.00 91.65  ? 36  ASN B ND2 1 
ATOM 2026 N N   . ILE B 2 47  ? 139.116 89.206  73.870  1.00 80.68  ? 37  ILE B N   1 
ATOM 2027 C CA  . ILE B 2 47  ? 138.651 90.536  74.246  1.00 79.26  ? 37  ILE B CA  1 
ATOM 2028 C C   . ILE B 2 47  ? 138.674 90.704  75.761  1.00 80.60  ? 37  ILE B C   1 
ATOM 2029 O O   . ILE B 2 47  ? 138.497 89.746  76.526  1.00 78.77  ? 37  ILE B O   1 
ATOM 2030 C CB  . ILE B 2 47  ? 137.245 90.810  73.684  1.00 76.92  ? 37  ILE B CB  1 
ATOM 2031 C CG1 . ILE B 2 47  ? 136.212 89.908  74.358  1.00 77.36  ? 37  ILE B CG1 1 
ATOM 2032 C CG2 . ILE B 2 47  ? 137.229 90.612  72.179  1.00 76.10  ? 37  ILE B CG2 1 
ATOM 2033 C CD1 . ILE B 2 47  ? 134.798 90.178  73.919  1.00 78.22  ? 37  ILE B CD1 1 
ATOM 2034 N N   . ASP B 2 48  ? 138.908 91.939  76.196  1.00 80.38  ? 38  ASP B N   1 
ATOM 2035 C CA  . ASP B 2 48  ? 138.970 92.243  77.614  1.00 79.50  ? 38  ASP B CA  1 
ATOM 2036 C C   . ASP B 2 48  ? 137.573 92.224  78.232  1.00 76.87  ? 38  ASP B C   1 
ATOM 2037 O O   . ASP B 2 48  ? 136.582 92.517  77.559  1.00 73.65  ? 38  ASP B O   1 
ATOM 2038 C CB  . ASP B 2 48  ? 139.610 93.610  77.835  1.00 79.50  ? 38  ASP B CB  1 
ATOM 2039 C CG  . ASP B 2 48  ? 140.984 93.717  77.209  1.00 82.82  ? 38  ASP B CG  1 
ATOM 2040 O OD1 . ASP B 2 48  ? 141.705 92.698  77.178  1.00 82.26  ? 38  ASP B OD1 1 
ATOM 2041 O OD2 . ASP B 2 48  ? 141.341 94.819  76.744  1.00 81.09  ? 38  ASP B OD2 1 
ATOM 2042 N N   . PRO B 2 49  ? 137.468 91.884  79.514  1.00 71.66  ? 39  PRO B N   1 
ATOM 2043 C CA  . PRO B 2 49  ? 136.163 91.916  80.177  1.00 68.18  ? 39  PRO B CA  1 
ATOM 2044 C C   . PRO B 2 49  ? 135.695 93.343  80.405  1.00 68.24  ? 39  PRO B C   1 
ATOM 2045 O O   . PRO B 2 49  ? 136.475 94.298  80.390  1.00 70.47  ? 39  PRO B O   1 
ATOM 2046 C CB  . PRO B 2 49  ? 136.420 91.196  81.504  1.00 70.37  ? 39  PRO B CB  1 
ATOM 2047 C CG  . PRO B 2 49  ? 137.872 91.393  81.754  1.00 67.60  ? 39  PRO B CG  1 
ATOM 2048 C CD  . PRO B 2 49  ? 138.526 91.377  80.403  1.00 68.22  ? 39  PRO B CD  1 
ATOM 2049 N N   . VAL B 2 50  ? 134.384 93.479  80.616  1.00 56.92  ? 40  VAL B N   1 
ATOM 2050 C CA  . VAL B 2 50  ? 133.796 94.784  80.889  1.00 58.15  ? 40  VAL B CA  1 
ATOM 2051 C C   . VAL B 2 50  ? 134.091 95.290  82.291  1.00 63.47  ? 40  VAL B C   1 
ATOM 2052 O O   . VAL B 2 50  ? 133.771 96.442  82.601  1.00 62.90  ? 40  VAL B O   1 
ATOM 2053 C CB  . VAL B 2 50  ? 132.274 94.741  80.661  1.00 51.54  ? 40  VAL B CB  1 
ATOM 2054 C CG1 . VAL B 2 50  ? 131.974 94.382  79.223  1.00 58.93  ? 40  VAL B CG1 1 
ATOM 2055 C CG2 . VAL B 2 50  ? 131.644 93.741  81.588  1.00 52.95  ? 40  VAL B CG2 1 
ATOM 2056 N N   . GLY B 2 51  ? 134.689 94.467  83.146  1.00 67.37  ? 41  GLY B N   1 
ATOM 2057 C CA  . GLY B 2 51  ? 134.912 94.869  84.518  1.00 61.30  ? 41  GLY B CA  1 
ATOM 2058 C C   . GLY B 2 51  ? 133.654 94.745  85.358  1.00 62.03  ? 41  GLY B C   1 
ATOM 2059 O O   . GLY B 2 51  ? 132.716 94.011  85.033  1.00 66.15  ? 41  GLY B O   1 
ATOM 2060 N N   . ARG B 2 52  ? 133.644 95.478  86.466  1.00 61.25  ? 42  ARG B N   1 
ATOM 2061 C CA  . ARG B 2 52  ? 132.490 95.516  87.350  1.00 60.40  ? 42  ARG B CA  1 
ATOM 2062 C C   . ARG B 2 52  ? 131.561 96.641  86.918  1.00 59.27  ? 42  ARG B C   1 
ATOM 2063 O O   . ARG B 2 52  ? 131.992 97.787  86.762  1.00 64.84  ? 42  ARG B O   1 
ATOM 2064 C CB  . ARG B 2 52  ? 132.927 95.714  88.801  1.00 64.18  ? 42  ARG B CB  1 
ATOM 2065 C CG  . ARG B 2 52  ? 131.786 95.717  89.809  1.00 64.42  ? 42  ARG B CG  1 
ATOM 2066 C CD  . ARG B 2 52  ? 131.145 94.347  89.947  1.00 66.77  ? 42  ARG B CD  1 
ATOM 2067 N NE  . ARG B 2 52  ? 130.094 94.338  90.958  1.00 67.64  ? 42  ARG B NE  1 
ATOM 2068 C CZ  . ARG B 2 52  ? 129.400 93.264  91.311  1.00 70.97  ? 42  ARG B CZ  1 
ATOM 2069 N NH1 . ARG B 2 52  ? 129.620 92.084  90.756  1.00 66.94  ? 42  ARG B NH1 1 
ATOM 2070 N NH2 . ARG B 2 52  ? 128.462 93.378  92.247  1.00 65.00  ? 42  ARG B NH2 1 
ATOM 2071 N N   . ILE B 2 53  ? 130.292 96.308  86.718  1.00 51.61  ? 43  ILE B N   1 
ATOM 2072 C CA  . ILE B 2 53  ? 129.273 97.269  86.319  1.00 51.25  ? 43  ILE B CA  1 
ATOM 2073 C C   . ILE B 2 53  ? 128.529 97.701  87.574  1.00 54.00  ? 43  ILE B C   1 
ATOM 2074 O O   . ILE B 2 53  ? 127.808 96.906  88.185  1.00 60.98  ? 43  ILE B O   1 
ATOM 2075 C CB  . ILE B 2 53  ? 128.315 96.676  85.278  1.00 51.33  ? 43  ILE B CB  1 
ATOM 2076 C CG1 . ILE B 2 53  ? 129.056 96.379  83.971  1.00 52.87  ? 43  ILE B CG1 1 
ATOM 2077 C CG2 . ILE B 2 53  ? 127.149 97.609  85.040  1.00 41.45  ? 43  ILE B CG2 1 
ATOM 2078 C CD1 . ILE B 2 53  ? 129.650 97.595  83.313  1.00 48.47  ? 43  ILE B CD1 1 
ATOM 2079 N N   . GLN B 2 54  ? 128.693 98.962  87.956  1.00 58.95  ? 44  GLN B N   1 
ATOM 2080 C CA  . GLN B 2 54  ? 128.047 99.525  89.134  1.00 57.88  ? 44  GLN B CA  1 
ATOM 2081 C C   . GLN B 2 54  ? 126.977 100.508 88.683  1.00 57.40  ? 44  GLN B C   1 
ATOM 2082 O O   . GLN B 2 54  ? 127.285 101.503 88.019  1.00 61.32  ? 44  GLN B O   1 
ATOM 2083 C CB  . GLN B 2 54  ? 129.064 100.224 90.036  1.00 61.72  ? 44  GLN B CB  1 
ATOM 2084 C CG  . GLN B 2 54  ? 130.072 99.303  90.696  1.00 60.91  ? 44  GLN B CG  1 
ATOM 2085 C CD  . GLN B 2 54  ? 129.502 98.579  91.897  1.00 68.69  ? 44  GLN B CD  1 
ATOM 2086 O OE1 . GLN B 2 54  ? 128.338 98.760  92.253  1.00 67.97  ? 44  GLN B OE1 1 
ATOM 2087 N NE2 . GLN B 2 54  ? 130.326 97.756  92.535  1.00 67.20  ? 44  GLN B NE2 1 
ATOM 2088 N N   . MET B 2 55  ? 125.729 100.232 89.042  1.00 39.79  ? 45  MET B N   1 
ATOM 2089 C CA  . MET B 2 55  ? 124.616 101.116 88.739  1.00 47.61  ? 45  MET B CA  1 
ATOM 2090 C C   . MET B 2 55  ? 123.910 101.493 90.031  1.00 51.18  ? 45  MET B C   1 
ATOM 2091 O O   . MET B 2 55  ? 123.696 100.645 90.902  1.00 57.09  ? 45  MET B O   1 
ATOM 2092 C CB  . MET B 2 55  ? 123.626 100.463 87.774  1.00 48.09  ? 45  MET B CB  1 
ATOM 2093 C CG  . MET B 2 55  ? 124.218 100.095 86.430  1.00 48.19  ? 45  MET B CG  1 
ATOM 2094 S SD  . MET B 2 55  ? 123.000 99.368  85.327  1.00 54.45  ? 45  MET B SD  1 
ATOM 2095 C CE  . MET B 2 55  ? 124.021 99.000  83.907  1.00 50.25  ? 45  MET B CE  1 
ATOM 2096 N N   . ARG B 2 56  ? 123.552 102.763 90.152  1.00 45.85  ? 46  ARG B N   1 
ATOM 2097 C CA  . ARG B 2 56  ? 122.852 103.269 91.318  1.00 43.91  ? 46  ARG B CA  1 
ATOM 2098 C C   . ARG B 2 56  ? 121.403 103.569 90.971  1.00 40.70  ? 46  ARG B C   1 
ATOM 2099 O O   . ARG B 2 56  ? 121.070 103.859 89.820  1.00 55.77  ? 46  ARG B O   1 
ATOM 2100 C CB  . ARG B 2 56  ? 123.516 104.536 91.858  1.00 48.30  ? 46  ARG B CB  1 
ATOM 2101 C CG  . ARG B 2 56  ? 124.922 104.346 92.391  1.00 52.08  ? 46  ARG B CG  1 
ATOM 2102 C CD  . ARG B 2 56  ? 125.399 105.602 93.110  1.00 56.53  ? 46  ARG B CD  1 
ATOM 2103 N NE  . ARG B 2 56  ? 124.603 105.890 94.299  1.00 63.19  ? 46  ARG B NE  1 
ATOM 2104 C CZ  . ARG B 2 56  ? 123.611 106.770 94.349  1.00 61.20  ? 46  ARG B CZ  1 
ATOM 2105 N NH1 . ARG B 2 56  ? 123.263 107.480 93.289  1.00 55.56  ? 46  ARG B NH1 1 
ATOM 2106 N NH2 . ARG B 2 56  ? 122.953 106.942 95.491  1.00 54.20  ? 46  ARG B NH2 1 
ATOM 2107 N N   . THR B 2 57  ? 120.543 103.500 91.979  1.00 37.12  ? 47  THR B N   1 
ATOM 2108 C CA  . THR B 2 57  ? 119.140 103.853 91.804  1.00 33.50  ? 47  THR B CA  1 
ATOM 2109 C C   . THR B 2 57  ? 119.053 105.370 91.743  1.00 43.59  ? 47  THR B C   1 
ATOM 2110 O O   . THR B 2 57  ? 119.131 106.052 92.766  1.00 50.83  ? 47  THR B O   1 
ATOM 2111 C CB  . THR B 2 57  ? 118.298 103.288 92.940  1.00 40.72  ? 47  THR B CB  1 
ATOM 2112 O OG1 . THR B 2 57  ? 118.396 101.860 92.937  1.00 50.18  ? 47  THR B OG1 1 
ATOM 2113 C CG2 . THR B 2 57  ? 116.847 103.689 92.780  1.00 38.46  ? 47  THR B CG2 1 
ATOM 2114 N N   . ARG B 2 58  ? 118.898 105.905 90.533  1.00 45.08  ? 48  ARG B N   1 
ATOM 2115 C CA  . ARG B 2 58  ? 118.742 107.344 90.375  1.00 45.83  ? 48  ARG B CA  1 
ATOM 2116 C C   . ARG B 2 58  ? 117.342 107.795 90.759  1.00 46.34  ? 48  ARG B C   1 
ATOM 2117 O O   . ARG B 2 58  ? 117.174 108.846 91.386  1.00 60.29  ? 48  ARG B O   1 
ATOM 2118 C CB  . ARG B 2 58  ? 119.056 107.748 88.937  1.00 44.24  ? 48  ARG B CB  1 
ATOM 2119 C CG  . ARG B 2 58  ? 120.410 107.280 88.452  1.00 45.60  ? 48  ARG B CG  1 
ATOM 2120 C CD  . ARG B 2 58  ? 121.527 107.847 89.302  1.00 44.95  ? 48  ARG B CD  1 
ATOM 2121 N NE  . ARG B 2 58  ? 122.837 107.467 88.790  1.00 51.47  ? 48  ARG B NE  1 
ATOM 2122 C CZ  . ARG B 2 58  ? 123.988 107.796 89.358  1.00 59.26  ? 48  ARG B CZ  1 
ATOM 2123 N NH1 . ARG B 2 58  ? 124.031 108.513 90.468  1.00 58.09  ? 48  ARG B NH1 1 
ATOM 2124 N NH2 . ARG B 2 58  ? 125.125 107.397 88.797  1.00 53.79  ? 48  ARG B NH2 1 
ATOM 2125 N N   . ARG B 2 59  ? 116.333 107.013 90.399  1.00 40.27  ? 49  ARG B N   1 
ATOM 2126 C CA  . ARG B 2 59  ? 114.944 107.340 90.667  1.00 42.76  ? 49  ARG B CA  1 
ATOM 2127 C C   . ARG B 2 59  ? 114.249 106.112 91.227  1.00 41.41  ? 49  ARG B C   1 
ATOM 2128 O O   . ARG B 2 59  ? 114.583 104.979 90.876  1.00 55.10  ? 49  ARG B O   1 
ATOM 2129 C CB  . ARG B 2 59  ? 114.210 107.805 89.402  1.00 47.83  ? 49  ARG B CB  1 
ATOM 2130 C CG  . ARG B 2 59  ? 114.861 108.950 88.650  1.00 40.52  ? 49  ARG B CG  1 
ATOM 2131 C CD  . ARG B 2 59  ? 114.833 110.237 89.447  1.00 46.52  ? 49  ARG B CD  1 
ATOM 2132 N NE  . ARG B 2 59  ? 115.130 111.392 88.610  1.00 52.41  ? 49  ARG B NE  1 
ATOM 2133 C CZ  . ARG B 2 59  ? 116.352 111.825 88.336  1.00 53.18  ? 49  ARG B CZ  1 
ATOM 2134 N NH1 . ARG B 2 59  ? 117.423 111.221 88.820  1.00 50.97  ? 49  ARG B NH1 1 
ATOM 2135 N NH2 . ARG B 2 59  ? 116.504 112.887 87.552  1.00 54.34  ? 49  ARG B NH2 1 
ATOM 2136 N N   . THR B 2 60  ? 113.284 106.343 92.108  1.00 36.47  ? 50  THR B N   1 
ATOM 2137 C CA  . THR B 2 60  ? 112.371 105.303 92.558  1.00 34.44  ? 50  THR B CA  1 
ATOM 2138 C C   . THR B 2 60  ? 110.957 105.778 92.278  1.00 45.07  ? 50  THR B C   1 
ATOM 2139 O O   . THR B 2 60  ? 110.537 106.821 92.788  1.00 49.58  ? 50  THR B O   1 
ATOM 2140 C CB  . THR B 2 60  ? 112.554 104.993 94.043  1.00 44.37  ? 50  THR B CB  1 
ATOM 2141 O OG1 . THR B 2 60  ? 113.899 104.564 94.279  1.00 47.98  ? 50  THR B OG1 1 
ATOM 2142 C CG2 . THR B 2 60  ? 111.601 103.895 94.468  1.00 47.05  ? 50  THR B CG2 1 
ATOM 2143 N N   . LEU B 2 61  ? 110.226 105.014 91.475  1.00 43.55  ? 51  LEU B N   1 
ATOM 2144 C CA  . LEU B 2 61  ? 108.870 105.374 91.088  1.00 37.64  ? 51  LEU B CA  1 
ATOM 2145 C C   . LEU B 2 61  ? 107.901 104.687 92.042  1.00 42.52  ? 51  LEU B C   1 
ATOM 2146 O O   . LEU B 2 61  ? 107.760 103.462 92.020  1.00 50.35  ? 51  LEU B O   1 
ATOM 2147 C CB  . LEU B 2 61  ? 108.613 104.975 89.639  1.00 35.08  ? 51  LEU B CB  1 
ATOM 2148 C CG  . LEU B 2 61  ? 109.692 105.429 88.653  1.00 39.54  ? 51  LEU B CG  1 
ATOM 2149 C CD1 . LEU B 2 61  ? 109.345 105.002 87.242  1.00 43.22  ? 51  LEU B CD1 1 
ATOM 2150 C CD2 . LEU B 2 61  ? 109.905 106.928 88.723  1.00 37.87  ? 51  LEU B CD2 1 
ATOM 2151 N N   . ARG B 2 62  ? 107.232 105.479 92.873  1.00 47.43  ? 52  ARG B N   1 
ATOM 2152 C CA  . ARG B 2 62  ? 106.313 104.988 93.885  1.00 49.95  ? 52  ARG B CA  1 
ATOM 2153 C C   . ARG B 2 62  ? 104.885 105.383 93.533  1.00 55.13  ? 52  ARG B C   1 
ATOM 2154 O O   . ARG B 2 62  ? 104.644 106.443 92.953  1.00 61.70  ? 52  ARG B O   1 
ATOM 2155 C CB  . ARG B 2 62  ? 106.675 105.542 95.264  1.00 55.71  ? 52  ARG B CB  1 
ATOM 2156 C CG  . ARG B 2 62  ? 108.146 105.430 95.611  1.00 59.33  ? 52  ARG B CG  1 
ATOM 2157 C CD  . ARG B 2 62  ? 108.456 106.153 96.908  1.00 56.39  ? 52  ARG B CD  1 
ATOM 2158 N NE  . ARG B 2 62  ? 109.886 106.191 97.187  1.00 61.77  ? 52  ARG B NE  1 
ATOM 2159 C CZ  . ARG B 2 62  ? 110.544 105.259 97.861  1.00 65.22  ? 52  ARG B CZ  1 
ATOM 2160 N NH1 . ARG B 2 62  ? 109.929 104.194 98.349  1.00 59.11  ? 52  ARG B NH1 1 
ATOM 2161 N NH2 . ARG B 2 62  ? 111.852 105.400 98.053  1.00 60.76  ? 52  ARG B NH2 1 
ATOM 2162 N N   . GLY B 2 63  ? 103.937 104.532 93.909  1.00 41.21  ? 53  GLY B N   1 
ATOM 2163 C CA  . GLY B 2 63  ? 102.544 104.798 93.614  1.00 39.04  ? 53  GLY B CA  1 
ATOM 2164 C C   . GLY B 2 63  ? 101.734 103.573 93.254  1.00 46.35  ? 53  GLY B C   1 
ATOM 2165 O O   . GLY B 2 63  ? 100.527 103.536 93.507  1.00 55.45  ? 53  GLY B O   1 
ATOM 2166 N N   . HIS B 2 64  ? 102.368 102.569 92.657  1.00 41.34  ? 54  HIS B N   1 
ATOM 2167 C CA  . HIS B 2 64  ? 101.722 101.272 92.509  1.00 34.55  ? 54  HIS B CA  1 
ATOM 2168 C C   . HIS B 2 64  ? 101.543 100.631 93.878  1.00 44.99  ? 54  HIS B C   1 
ATOM 2169 O O   . HIS B 2 64  ? 102.461 100.637 94.702  1.00 47.15  ? 54  HIS B O   1 
ATOM 2170 C CB  . HIS B 2 64  ? 102.538 100.364 91.594  1.00 33.01  ? 54  HIS B CB  1 
ATOM 2171 C CG  . HIS B 2 64  ? 102.424 100.706 90.141  1.00 43.20  ? 54  HIS B CG  1 
ATOM 2172 N ND1 . HIS B 2 64  ? 101.219 100.723 89.473  1.00 35.08  ? 54  HIS B ND1 1 
ATOM 2173 C CD2 . HIS B 2 64  ? 103.365 101.034 89.226  1.00 48.10  ? 54  HIS B CD2 1 
ATOM 2174 C CE1 . HIS B 2 64  ? 101.423 101.051 88.211  1.00 35.62  ? 54  HIS B CE1 1 
ATOM 2175 N NE2 . HIS B 2 64  ? 102.716 101.245 88.035  1.00 45.38  ? 54  HIS B NE2 1 
ATOM 2176 N N   . LEU B 2 65  ? 100.357 100.075 94.125  1.00 53.15  ? 55  LEU B N   1 
ATOM 2177 C CA  . LEU B 2 65  ? 100.026 99.502  95.422  1.00 49.01  ? 55  LEU B CA  1 
ATOM 2178 C C   . LEU B 2 65  ? 99.904  97.984  95.376  1.00 50.08  ? 55  LEU B C   1 
ATOM 2179 O O   . LEU B 2 65  ? 99.351  97.380  96.298  1.00 56.59  ? 55  LEU B O   1 
ATOM 2180 C CB  . LEU B 2 65  ? 98.743  100.127 95.967  1.00 46.12  ? 55  LEU B CB  1 
ATOM 2181 C CG  . LEU B 2 65  ? 98.871  101.616 96.283  1.00 45.59  ? 55  LEU B CG  1 
ATOM 2182 C CD1 . LEU B 2 65  ? 97.645  102.111 97.009  1.00 54.86  ? 55  LEU B CD1 1 
ATOM 2183 C CD2 . LEU B 2 65  ? 100.119 101.877 97.104  1.00 45.09  ? 55  LEU B CD2 1 
ATOM 2184 N N   . ALA B 2 66  ? 100.411 97.358  94.320  1.00 42.30  ? 56  ALA B N   1 
ATOM 2185 C CA  . ALA B 2 66  ? 100.388 95.911  94.188  1.00 36.33  ? 56  ALA B CA  1 
ATOM 2186 C C   . ALA B 2 66  ? 101.591 95.504  93.350  1.00 38.43  ? 56  ALA B C   1 
ATOM 2187 O O   . ALA B 2 66  ? 102.426 96.339  92.993  1.00 44.44  ? 56  ALA B O   1 
ATOM 2188 C CB  . ALA B 2 66  ? 99.064  95.437  93.580  1.00 38.38  ? 56  ALA B CB  1 
ATOM 2189 N N   . LYS B 2 67  ? 101.684 94.218  93.034  1.00 37.78  ? 57  LYS B N   1 
ATOM 2190 C CA  . LYS B 2 67  ? 102.810 93.735  92.249  1.00 33.98  ? 57  LYS B CA  1 
ATOM 2191 C C   . LYS B 2 67  ? 102.804 94.370  90.865  1.00 45.45  ? 57  LYS B C   1 
ATOM 2192 O O   . LYS B 2 67  ? 101.768 94.432  90.199  1.00 58.16  ? 57  LYS B O   1 
ATOM 2193 C CB  . LYS B 2 67  ? 102.761 92.210  92.152  1.00 39.19  ? 57  LYS B CB  1 
ATOM 2194 C CG  . LYS B 2 67  ? 102.910 91.531  93.504  1.00 40.90  ? 57  LYS B CG  1 
ATOM 2195 C CD  . LYS B 2 67  ? 102.142 90.225  93.604  1.00 41.28  ? 57  LYS B CD  1 
ATOM 2196 C CE  . LYS B 2 67  ? 102.773 89.134  92.770  1.00 44.86  ? 57  LYS B CE  1 
ATOM 2197 N NZ  . LYS B 2 67  ? 102.082 87.831  92.955  1.00 44.36  ? 57  LYS B NZ  1 
ATOM 2198 N N   . ILE B 2 68  ? 103.967 94.841  90.437  1.00 32.71  ? 58  ILE B N   1 
ATOM 2199 C CA  . ILE B 2 68  ? 104.169 95.321  89.076  1.00 28.35  ? 58  ILE B CA  1 
ATOM 2200 C C   . ILE B 2 68  ? 104.561 94.146  88.197  1.00 38.51  ? 58  ILE B C   1 
ATOM 2201 O O   . ILE B 2 68  ? 105.478 93.387  88.532  1.00 41.19  ? 58  ILE B O   1 
ATOM 2202 C CB  . ILE B 2 68  ? 105.238 96.425  89.035  1.00 32.66  ? 58  ILE B CB  1 
ATOM 2203 C CG1 . ILE B 2 68  ? 104.791 97.623  89.868  1.00 25.07  ? 58  ILE B CG1 1 
ATOM 2204 C CG2 . ILE B 2 68  ? 105.533 96.836  87.607  1.00 37.78  ? 58  ILE B CG2 1 
ATOM 2205 C CD1 . ILE B 2 68  ? 105.803 98.712  89.930  1.00 37.07  ? 58  ILE B CD1 1 
ATOM 2206 N N   . TYR B 2 69  ? 103.865 93.989  87.071  1.00 42.42  ? 59  TYR B N   1 
ATOM 2207 C CA  . TYR B 2 69  ? 104.102 92.861  86.186  1.00 39.70  ? 59  TYR B CA  1 
ATOM 2208 C C   . TYR B 2 69  ? 104.783 93.226  84.878  1.00 42.64  ? 59  TYR B C   1 
ATOM 2209 O O   . TYR B 2 69  ? 105.393 92.350  84.260  1.00 45.33  ? 59  TYR B O   1 
ATOM 2210 C CB  . TYR B 2 69  ? 102.784 92.140  85.881  1.00 38.27  ? 59  TYR B CB  1 
ATOM 2211 C CG  . TYR B 2 69  ? 102.458 91.079  86.900  1.00 46.12  ? 59  TYR B CG  1 
ATOM 2212 C CD1 . TYR B 2 69  ? 101.929 91.419  88.134  1.00 44.94  ? 59  TYR B CD1 1 
ATOM 2213 C CD2 . TYR B 2 69  ? 102.707 89.742  86.641  1.00 44.24  ? 59  TYR B CD2 1 
ATOM 2214 C CE1 . TYR B 2 69  ? 101.643 90.457  89.075  1.00 45.35  ? 59  TYR B CE1 1 
ATOM 2215 C CE2 . TYR B 2 69  ? 102.423 88.773  87.575  1.00 48.70  ? 59  TYR B CE2 1 
ATOM 2216 C CZ  . TYR B 2 69  ? 101.889 89.135  88.791  1.00 48.65  ? 59  TYR B CZ  1 
ATOM 2217 O OH  . TYR B 2 69  ? 101.604 88.172  89.727  1.00 45.72  ? 59  TYR B OH  1 
ATOM 2218 N N   . ALA B 2 70  ? 104.710 94.481  84.447  1.00 40.64  ? 60  ALA B N   1 
ATOM 2219 C CA  . ALA B 2 70  ? 105.318 94.857  83.181  1.00 31.46  ? 60  ALA B CA  1 
ATOM 2220 C C   . ALA B 2 70  ? 105.615 96.347  83.186  1.00 39.46  ? 60  ALA B C   1 
ATOM 2221 O O   . ALA B 2 70  ? 104.957 97.125  83.879  1.00 44.87  ? 60  ALA B O   1 
ATOM 2222 C CB  . ALA B 2 70  ? 104.421 94.502  81.996  1.00 36.69  ? 60  ALA B CB  1 
ATOM 2223 N N   . MET B 2 71  ? 106.622 96.725  82.404  1.00 43.89  ? 61  MET B N   1 
ATOM 2224 C CA  . MET B 2 71  ? 106.943 98.118  82.145  1.00 33.48  ? 61  MET B CA  1 
ATOM 2225 C C   . MET B 2 71  ? 107.490 98.207  80.731  1.00 43.95  ? 61  MET B C   1 
ATOM 2226 O O   . MET B 2 71  ? 108.023 97.230  80.198  1.00 39.83  ? 61  MET B O   1 
ATOM 2227 C CB  . MET B 2 71  ? 107.939 98.682  83.169  1.00 22.64  ? 61  MET B CB  1 
ATOM 2228 C CG  . MET B 2 71  ? 109.302 98.005  83.210  1.00 40.10  ? 61  MET B CG  1 
ATOM 2229 S SD  . MET B 2 71  ? 110.475 98.635  81.997  1.00 49.66  ? 61  MET B SD  1 
ATOM 2230 C CE  . MET B 2 71  ? 110.226 100.396 82.179  1.00 43.21  ? 61  MET B CE  1 
ATOM 2231 N N   . HIS B 2 72  ? 107.361 99.383  80.125  1.00 37.62  ? 62  HIS B N   1 
ATOM 2232 C CA  . HIS B 2 72  ? 107.920 99.592  78.798  1.00 30.21  ? 62  HIS B CA  1 
ATOM 2233 C C   . HIS B 2 72  ? 108.313 101.050 78.634  1.00 29.60  ? 62  HIS B C   1 
ATOM 2234 O O   . HIS B 2 72  ? 107.509 101.944 78.907  1.00 33.14  ? 62  HIS B O   1 
ATOM 2235 C CB  . HIS B 2 72  ? 106.914 99.190  77.716  1.00 23.64  ? 62  HIS B CB  1 
ATOM 2236 C CG  . HIS B 2 72  ? 107.530 98.970  76.371  1.00 25.16  ? 62  HIS B CG  1 
ATOM 2237 N ND1 . HIS B 2 72  ? 106.917 99.351  75.200  1.00 17.09  ? 62  HIS B ND1 1 
ATOM 2238 C CD2 . HIS B 2 72  ? 108.700 98.394  76.012  1.00 29.54  ? 62  HIS B CD2 1 
ATOM 2239 C CE1 . HIS B 2 72  ? 107.685 99.027  74.177  1.00 23.75  ? 62  HIS B CE1 1 
ATOM 2240 N NE2 . HIS B 2 72  ? 108.773 98.444  74.643  1.00 32.92  ? 62  HIS B NE2 1 
ATOM 2241 N N   . TRP B 2 73  ? 109.545 101.280 78.192  1.00 27.55  ? 63  TRP B N   1 
ATOM 2242 C CA  . TRP B 2 73  ? 110.002 102.626 77.894  1.00 33.08  ? 63  TRP B CA  1 
ATOM 2243 C C   . TRP B 2 73  ? 109.327 103.151 76.635  1.00 32.26  ? 63  TRP B C   1 
ATOM 2244 O O   . TRP B 2 73  ? 109.066 102.409 75.688  1.00 36.91  ? 63  TRP B O   1 
ATOM 2245 C CB  . TRP B 2 73  ? 111.516 102.660 77.695  1.00 32.66  ? 63  TRP B CB  1 
ATOM 2246 C CG  . TRP B 2 73  ? 112.324 102.545 78.938  1.00 29.93  ? 63  TRP B CG  1 
ATOM 2247 C CD1 . TRP B 2 73  ? 112.907 101.420 79.430  1.00 30.81  ? 63  TRP B CD1 1 
ATOM 2248 C CD2 . TRP B 2 73  ? 112.646 103.596 79.852  1.00 33.90  ? 63  TRP B CD2 1 
ATOM 2249 N NE1 . TRP B 2 73  ? 113.575 101.701 80.592  1.00 35.45  ? 63  TRP B NE1 1 
ATOM 2250 C CE2 . TRP B 2 73  ? 113.428 103.032 80.875  1.00 35.79  ? 63  TRP B CE2 1 
ATOM 2251 C CE3 . TRP B 2 73  ? 112.348 104.959 79.904  1.00 30.43  ? 63  TRP B CE3 1 
ATOM 2252 C CZ2 . TRP B 2 73  ? 113.918 103.783 81.936  1.00 25.36  ? 63  TRP B CZ2 1 
ATOM 2253 C CZ3 . TRP B 2 73  ? 112.833 105.700 80.958  1.00 34.13  ? 63  TRP B CZ3 1 
ATOM 2254 C CH2 . TRP B 2 73  ? 113.609 105.112 81.961  1.00 28.74  ? 63  TRP B CH2 1 
ATOM 2255 N N   . GLY B 2 74  ? 109.059 104.452 76.625  1.00 43.16  ? 64  GLY B N   1 
ATOM 2256 C CA  . GLY B 2 74  ? 108.745 105.117 75.384  1.00 43.56  ? 64  GLY B CA  1 
ATOM 2257 C C   . GLY B 2 74  ? 109.980 105.364 74.545  1.00 47.90  ? 64  GLY B C   1 
ATOM 2258 O O   . GLY B 2 74  ? 111.113 105.267 75.011  1.00 53.16  ? 64  GLY B O   1 
ATOM 2259 N N   . THR B 2 75  ? 109.756 105.681 73.270  1.00 38.88  ? 65  THR B N   1 
ATOM 2260 C CA  . THR B 2 75  ? 110.874 105.832 72.349  1.00 43.87  ? 65  THR B CA  1 
ATOM 2261 C C   . THR B 2 75  ? 111.666 107.107 72.590  1.00 50.13  ? 65  THR B C   1 
ATOM 2262 O O   . THR B 2 75  ? 112.778 107.230 72.067  1.00 51.69  ? 65  THR B O   1 
ATOM 2263 C CB  . THR B 2 75  ? 110.382 105.786 70.904  1.00 43.26  ? 65  THR B CB  1 
ATOM 2264 O OG1 . THR B 2 75  ? 109.138 106.489 70.795  1.00 53.43  ? 65  THR B OG1 1 
ATOM 2265 C CG2 . THR B 2 75  ? 110.195 104.349 70.458  1.00 40.25  ? 65  THR B CG2 1 
ATOM 2266 N N   . ASP B 2 76  ? 111.129 108.053 73.355  1.00 47.70  ? 66  ASP B N   1 
ATOM 2267 C CA  . ASP B 2 76  ? 111.858 109.264 73.700  1.00 45.42  ? 66  ASP B CA  1 
ATOM 2268 C C   . ASP B 2 76  ? 112.826 109.051 74.854  1.00 49.19  ? 66  ASP B C   1 
ATOM 2269 O O   . ASP B 2 76  ? 113.521 109.998 75.239  1.00 51.65  ? 66  ASP B O   1 
ATOM 2270 C CB  . ASP B 2 76  ? 110.885 110.392 74.043  1.00 50.37  ? 66  ASP B CB  1 
ATOM 2271 C CG  . ASP B 2 76  ? 110.075 110.103 75.282  1.00 49.45  ? 66  ASP B CG  1 
ATOM 2272 O OD1 . ASP B 2 76  ? 109.795 108.919 75.546  1.00 48.58  ? 66  ASP B OD1 1 
ATOM 2273 O OD2 . ASP B 2 76  ? 109.717 111.062 75.992  1.00 49.50  ? 66  ASP B OD2 1 
ATOM 2274 N N   . SER B 2 77  ? 112.874 107.840 75.411  1.00 38.61  ? 67  SER B N   1 
ATOM 2275 C CA  . SER B 2 77  ? 113.770 107.463 76.501  1.00 36.13  ? 67  SER B CA  1 
ATOM 2276 C C   . SER B 2 77  ? 113.497 108.237 77.786  1.00 40.18  ? 67  SER B C   1 
ATOM 2277 O O   . SER B 2 77  ? 114.343 108.267 78.685  1.00 49.86  ? 67  SER B O   1 
ATOM 2278 C CB  . SER B 2 77  ? 115.233 107.628 76.089  1.00 43.64  ? 67  SER B CB  1 
ATOM 2279 O OG  . SER B 2 77  ? 115.524 106.849 74.946  1.00 43.85  ? 67  SER B OG  1 
ATOM 2280 N N   . ARG B 2 78  ? 112.336 108.865 77.894  1.00 33.24  ? 68  ARG B N   1 
ATOM 2281 C CA  . ARG B 2 78  ? 111.965 109.622 79.082  1.00 40.75  ? 68  ARG B CA  1 
ATOM 2282 C C   . ARG B 2 78  ? 110.663 109.153 79.706  1.00 38.95  ? 68  ARG B C   1 
ATOM 2283 O O   . ARG B 2 78  ? 110.566 109.077 80.932  1.00 38.19  ? 68  ARG B O   1 
ATOM 2284 C CB  . ARG B 2 78  ? 111.857 111.118 78.756  1.00 43.65  ? 68  ARG B CB  1 
ATOM 2285 C CG  . ARG B 2 78  ? 111.331 111.939 79.913  1.00 39.02  ? 68  ARG B CG  1 
ATOM 2286 C CD  . ARG B 2 78  ? 111.498 113.423 79.699  1.00 43.63  ? 68  ARG B CD  1 
ATOM 2287 N NE  . ARG B 2 78  ? 111.066 114.170 80.873  1.00 43.80  ? 68  ARG B NE  1 
ATOM 2288 C CZ  . ARG B 2 78  ? 111.281 115.464 81.060  1.00 39.27  ? 68  ARG B CZ  1 
ATOM 2289 N NH1 . ARG B 2 78  ? 111.933 116.190 80.169  1.00 40.83  ? 68  ARG B NH1 1 
ATOM 2290 N NH2 . ARG B 2 78  ? 110.835 116.041 82.170  1.00 42.03  ? 68  ARG B NH2 1 
ATOM 2291 N N   . LEU B 2 79  ? 109.661 108.834 78.897  1.00 35.91  ? 69  LEU B N   1 
ATOM 2292 C CA  . LEU B 2 79  ? 108.392 108.344 79.405  1.00 24.26  ? 69  LEU B CA  1 
ATOM 2293 C C   . LEU B 2 79  ? 108.381 106.824 79.413  1.00 37.14  ? 69  LEU B C   1 
ATOM 2294 O O   . LEU B 2 79  ? 108.922 106.180 78.511  1.00 51.87  ? 69  LEU B O   1 
ATOM 2295 C CB  . LEU B 2 79  ? 107.236 108.869 78.555  1.00 23.50  ? 69  LEU B CB  1 
ATOM 2296 C CG  . LEU B 2 79  ? 106.996 110.376 78.577  1.00 33.45  ? 69  LEU B CG  1 
ATOM 2297 C CD1 . LEU B 2 79  ? 105.851 110.742 77.662  1.00 29.93  ? 69  LEU B CD1 1 
ATOM 2298 C CD2 . LEU B 2 79  ? 106.710 110.840 79.987  1.00 41.77  ? 69  LEU B CD2 1 
ATOM 2299 N N   . LEU B 2 80  ? 107.764 106.256 80.443  1.00 35.73  ? 70  LEU B N   1 
ATOM 2300 C CA  . LEU B 2 80  ? 107.581 104.819 80.538  1.00 27.97  ? 70  LEU B CA  1 
ATOM 2301 C C   . LEU B 2 80  ? 106.213 104.535 81.132  1.00 33.64  ? 70  LEU B C   1 
ATOM 2302 O O   . LEU B 2 80  ? 105.660 105.349 81.873  1.00 37.53  ? 70  LEU B O   1 
ATOM 2303 C CB  . LEU B 2 80  ? 108.681 104.162 81.384  1.00 31.09  ? 70  LEU B CB  1 
ATOM 2304 C CG  . LEU B 2 80  ? 108.775 104.542 82.861  1.00 38.18  ? 70  LEU B CG  1 
ATOM 2305 C CD1 . LEU B 2 80  ? 108.118 103.495 83.744  1.00 38.07  ? 70  LEU B CD1 1 
ATOM 2306 C CD2 . LEU B 2 80  ? 110.218 104.745 83.260  1.00 38.42  ? 70  LEU B CD2 1 
ATOM 2307 N N   . VAL B 2 81  ? 105.672 103.372 80.792  1.00 38.01  ? 71  VAL B N   1 
ATOM 2308 C CA  . VAL B 2 81  ? 104.390 102.905 81.303  1.00 40.52  ? 71  VAL B CA  1 
ATOM 2309 C C   . VAL B 2 81  ? 104.638 101.640 82.108  1.00 37.54  ? 71  VAL B C   1 
ATOM 2310 O O   . VAL B 2 81  ? 105.424 100.780 81.699  1.00 45.12  ? 71  VAL B O   1 
ATOM 2311 C CB  . VAL B 2 81  ? 103.370 102.656 80.170  1.00 26.36  ? 71  VAL B CB  1 
ATOM 2312 C CG1 . VAL B 2 81  ? 103.922 101.690 79.144  1.00 18.51  ? 71  VAL B CG1 1 
ATOM 2313 C CG2 . VAL B 2 81  ? 102.062 102.146 80.729  1.00 27.34  ? 71  VAL B CG2 1 
ATOM 2314 N N   . SER B 2 82  ? 103.999 101.540 83.267  1.00 27.36  ? 72  SER B N   1 
ATOM 2315 C CA  . SER B 2 82  ? 104.103 100.352 84.096  1.00 18.55  ? 72  SER B CA  1 
ATOM 2316 C C   . SER B 2 82  ? 102.710 99.839  84.410  1.00 32.98  ? 72  SER B C   1 
ATOM 2317 O O   . SER B 2 82  ? 101.757 100.611 84.530  1.00 43.52  ? 72  SER B O   1 
ATOM 2318 C CB  . SER B 2 82  ? 104.860 100.623 85.397  1.00 28.83  ? 72  SER B CB  1 
ATOM 2319 O OG  . SER B 2 82  ? 104.203 101.596 86.182  1.00 37.46  ? 72  SER B OG  1 
ATOM 2320 N N   . ALA B 2 83  ? 102.600 98.521  84.529  1.00 38.67  ? 73  ALA B N   1 
ATOM 2321 C CA  . ALA B 2 83  ? 101.338 97.865  84.827  1.00 31.20  ? 73  ALA B CA  1 
ATOM 2322 C C   . ALA B 2 83  ? 101.453 97.146  86.158  1.00 35.43  ? 73  ALA B C   1 
ATOM 2323 O O   . ALA B 2 83  ? 102.446 96.459  86.414  1.00 46.53  ? 73  ALA B O   1 
ATOM 2324 C CB  . ALA B 2 83  ? 100.954 96.874  83.727  1.00 29.75  ? 73  ALA B CB  1 
ATOM 2325 N N   . SER B 2 84  ? 100.440 97.305  86.997  1.00 38.21  ? 74  SER B N   1 
ATOM 2326 C CA  . SER B 2 84  ? 100.374 96.627  88.277  1.00 41.42  ? 74  SER B CA  1 
ATOM 2327 C C   . SER B 2 84  ? 98.992  96.015  88.428  1.00 41.73  ? 74  SER B C   1 
ATOM 2328 O O   . SER B 2 84  ? 98.033  96.427  87.772  1.00 42.53  ? 74  SER B O   1 
ATOM 2329 C CB  . SER B 2 84  ? 100.665 97.573  89.442  1.00 43.02  ? 74  SER B CB  1 
ATOM 2330 O OG  . SER B 2 84  ? 100.578 96.898  90.680  1.00 49.95  ? 74  SER B OG  1 
ATOM 2331 N N   . GLN B 2 85  ? 98.893  95.026  89.309  1.00 40.05  ? 75  GLN B N   1 
ATOM 2332 C CA  . GLN B 2 85  ? 97.627  94.357  89.553  1.00 49.08  ? 75  GLN B CA  1 
ATOM 2333 C C   . GLN B 2 85  ? 96.793  95.047  90.622  1.00 48.22  ? 75  GLN B C   1 
ATOM 2334 O O   . GLN B 2 85  ? 95.913  94.414  91.214  1.00 46.68  ? 75  GLN B O   1 
ATOM 2335 C CB  . GLN B 2 85  ? 97.871  92.892  89.905  1.00 48.28  ? 75  GLN B CB  1 
ATOM 2336 C CG  . GLN B 2 85  ? 98.441  92.112  88.739  1.00 45.96  ? 75  GLN B CG  1 
ATOM 2337 C CD  . GLN B 2 85  ? 98.358  90.622  88.935  1.00 52.54  ? 75  GLN B CD  1 
ATOM 2338 O OE1 . GLN B 2 85  ? 98.280  90.137  90.063  1.00 56.69  ? 75  GLN B OE1 1 
ATOM 2339 N NE2 . GLN B 2 85  ? 98.370  89.881  87.836  1.00 45.44  ? 75  GLN B NE2 1 
ATOM 2340 N N   . ASP B 2 86  ? 97.044  96.327  90.873  1.00 47.06  ? 76  ASP B N   1 
ATOM 2341 C CA  . ASP B 2 86  ? 96.075  97.194  91.523  1.00 50.21  ? 76  ASP B CA  1 
ATOM 2342 C C   . ASP B 2 86  ? 95.087  97.793  90.531  1.00 56.73  ? 76  ASP B C   1 
ATOM 2343 O O   . ASP B 2 86  ? 94.311  98.679  90.902  1.00 63.07  ? 76  ASP B O   1 
ATOM 2344 C CB  . ASP B 2 86  ? 96.791  98.302  92.299  1.00 46.15  ? 76  ASP B CB  1 
ATOM 2345 C CG  . ASP B 2 86  ? 97.764  99.078  91.443  1.00 52.80  ? 76  ASP B CG  1 
ATOM 2346 O OD1 . ASP B 2 86  ? 97.894  98.755  90.249  1.00 58.04  ? 76  ASP B OD1 1 
ATOM 2347 O OD2 . ASP B 2 86  ? 98.403  100.015 91.964  1.00 61.48  ? 76  ASP B OD2 1 
ATOM 2348 N N   . GLY B 2 87  ? 95.095  97.321  89.287  1.00 42.65  ? 77  GLY B N   1 
ATOM 2349 C CA  . GLY B 2 87  ? 94.206  97.835  88.264  1.00 39.55  ? 77  GLY B CA  1 
ATOM 2350 C C   . GLY B 2 87  ? 94.551  99.211  87.750  1.00 40.19  ? 77  GLY B C   1 
ATOM 2351 O O   . GLY B 2 87  ? 93.657  99.944  87.323  1.00 50.10  ? 77  GLY B O   1 
ATOM 2352 N N   . LYS B 2 88  ? 95.826  99.586  87.778  1.00 48.38  ? 78  LYS B N   1 
ATOM 2353 C CA  . LYS B 2 88  ? 96.254  100.918 87.375  1.00 47.59  ? 78  LYS B CA  1 
ATOM 2354 C C   . LYS B 2 88  ? 97.379  100.807 86.362  1.00 46.67  ? 78  LYS B C   1 
ATOM 2355 O O   . LYS B 2 88  ? 98.386  100.140 86.618  1.00 50.70  ? 78  LYS B O   1 
ATOM 2356 C CB  . LYS B 2 88  ? 96.718  101.738 88.582  1.00 40.49  ? 78  LYS B CB  1 
ATOM 2357 C CG  . LYS B 2 88  ? 95.603  102.167 89.508  1.00 42.56  ? 78  LYS B CG  1 
ATOM 2358 C CD  . LYS B 2 88  ? 94.662  103.118 88.810  1.00 49.21  ? 78  LYS B CD  1 
ATOM 2359 C CE  . LYS B 2 88  ? 93.550  103.561 89.736  1.00 48.87  ? 78  LYS B CE  1 
ATOM 2360 N NZ  . LYS B 2 88  ? 92.658  104.554 89.081  1.00 51.40  ? 78  LYS B NZ  1 
ATOM 2361 N N   . LEU B 2 89  ? 97.200  101.451 85.214  1.00 35.73  ? 79  LEU B N   1 
ATOM 2362 C CA  . LEU B 2 89  ? 98.281  101.724 84.280  1.00 30.43  ? 79  LEU B CA  1 
ATOM 2363 C C   . LEU B 2 89  ? 98.772  103.144 84.535  1.00 35.29  ? 79  LEU B C   1 
ATOM 2364 O O   . LEU B 2 89  ? 97.983  104.091 84.478  1.00 50.34  ? 79  LEU B O   1 
ATOM 2365 C CB  . LEU B 2 89  ? 97.799  101.557 82.841  1.00 41.70  ? 79  LEU B CB  1 
ATOM 2366 C CG  . LEU B 2 89  ? 98.784  101.042 81.796  1.00 39.20  ? 79  LEU B CG  1 
ATOM 2367 C CD1 . LEU B 2 89  ? 99.211  99.631  82.131  1.00 46.04  ? 79  LEU B CD1 1 
ATOM 2368 C CD2 . LEU B 2 89  ? 98.162  101.092 80.416  1.00 38.69  ? 79  LEU B CD2 1 
ATOM 2369 N N   . ILE B 2 90  ? 100.062 103.295 84.823  1.00 27.45  ? 80  ILE B N   1 
ATOM 2370 C CA  . ILE B 2 90  ? 100.647 104.595 85.128  1.00 32.42  ? 80  ILE B CA  1 
ATOM 2371 C C   . ILE B 2 90  ? 101.729 104.899 84.105  1.00 42.30  ? 80  ILE B C   1 
ATOM 2372 O O   . ILE B 2 90  ? 102.563 104.040 83.799  1.00 37.05  ? 80  ILE B O   1 
ATOM 2373 C CB  . ILE B 2 90  ? 101.216 104.653 86.557  1.00 27.23  ? 80  ILE B CB  1 
ATOM 2374 C CG1 . ILE B 2 90  ? 100.125 104.343 87.580  1.00 35.24  ? 80  ILE B CG1 1 
ATOM 2375 C CG2 . ILE B 2 90  ? 101.794 106.020 86.840  1.00 26.94  ? 80  ILE B CG2 1 
ATOM 2376 C CD1 . ILE B 2 90  ? 100.589 104.460 89.008  1.00 30.66  ? 80  ILE B CD1 1 
ATOM 2377 N N   . ILE B 2 91  ? 101.716 106.124 83.588  1.00 39.82  ? 81  ILE B N   1 
ATOM 2378 C CA  . ILE B 2 91  ? 102.751 106.633 82.699  1.00 26.29  ? 81  ILE B CA  1 
ATOM 2379 C C   . ILE B 2 91  ? 103.608 107.597 83.502  1.00 32.27  ? 81  ILE B C   1 
ATOM 2380 O O   . ILE B 2 91  ? 103.093 108.551 84.097  1.00 35.31  ? 81  ILE B O   1 
ATOM 2381 C CB  . ILE B 2 91  ? 102.147 107.307 81.461  1.00 32.64  ? 81  ILE B CB  1 
ATOM 2382 C CG1 . ILE B 2 91  ? 101.375 106.274 80.644  1.00 34.65  ? 81  ILE B CG1 1 
ATOM 2383 C CG2 . ILE B 2 91  ? 103.228 107.959 80.621  1.00 29.38  ? 81  ILE B CG2 1 
ATOM 2384 C CD1 . ILE B 2 91  ? 100.761 106.827 79.410  1.00 42.65  ? 81  ILE B CD1 1 
ATOM 2385 N N   . TRP B 2 92  ? 104.910 107.340 83.533  1.00 37.77  ? 82  TRP B N   1 
ATOM 2386 C CA  . TRP B 2 92  ? 105.841 108.066 84.380  1.00 28.79  ? 82  TRP B CA  1 
ATOM 2387 C C   . TRP B 2 92  ? 106.724 108.981 83.549  1.00 27.74  ? 82  TRP B C   1 
ATOM 2388 O O   . TRP B 2 92  ? 107.136 108.629 82.442  1.00 45.48  ? 82  TRP B O   1 
ATOM 2389 C CB  . TRP B 2 92  ? 106.734 107.106 85.169  1.00 36.19  ? 82  TRP B CB  1 
ATOM 2390 C CG  . TRP B 2 92  ? 106.003 106.101 85.980  1.00 33.75  ? 82  TRP B CG  1 
ATOM 2391 C CD1 . TRP B 2 92  ? 105.486 104.921 85.546  1.00 37.76  ? 82  TRP B CD1 1 
ATOM 2392 C CD2 . TRP B 2 92  ? 105.723 106.173 87.377  1.00 35.91  ? 82  TRP B CD2 1 
ATOM 2393 N NE1 . TRP B 2 92  ? 104.890 104.255 86.585  1.00 34.51  ? 82  TRP B NE1 1 
ATOM 2394 C CE2 . TRP B 2 92  ? 105.023 105.005 87.722  1.00 40.89  ? 82  TRP B CE2 1 
ATOM 2395 C CE3 . TRP B 2 92  ? 105.991 107.117 88.372  1.00 29.60  ? 82  TRP B CE3 1 
ATOM 2396 C CZ2 . TRP B 2 92  ? 104.590 104.753 89.016  1.00 37.86  ? 82  TRP B CZ2 1 
ATOM 2397 C CZ3 . TRP B 2 92  ? 105.560 106.865 89.653  1.00 24.88  ? 82  TRP B CZ3 1 
ATOM 2398 C CH2 . TRP B 2 92  ? 104.867 105.694 89.964  1.00 36.96  ? 82  TRP B CH2 1 
ATOM 2399 N N   . ASP B 2 93  ? 106.997 110.163 84.089  1.00 39.09  ? 83  ASP B N   1 
ATOM 2400 C CA  . ASP B 2 93  ? 108.080 111.013 83.608  1.00 35.47  ? 83  ASP B CA  1 
ATOM 2401 C C   . ASP B 2 93  ? 109.320 110.607 84.393  1.00 45.22  ? 83  ASP B C   1 
ATOM 2402 O O   . ASP B 2 93  ? 109.474 110.969 85.559  1.00 57.11  ? 83  ASP B O   1 
ATOM 2403 C CB  . ASP B 2 93  ? 107.729 112.484 83.802  1.00 29.47  ? 83  ASP B CB  1 
ATOM 2404 C CG  . ASP B 2 93  ? 108.757 113.416 83.208  1.00 46.12  ? 83  ASP B CG  1 
ATOM 2405 O OD1 . ASP B 2 93  ? 109.654 112.939 82.486  1.00 56.82  ? 83  ASP B OD1 1 
ATOM 2406 O OD2 . ASP B 2 93  ? 108.667 114.634 83.460  1.00 48.60  ? 83  ASP B OD2 1 
ATOM 2407 N N   . SER B 2 94  ? 110.208 109.839 83.760  1.00 44.12  ? 84  SER B N   1 
ATOM 2408 C CA  . SER B 2 94  ? 111.324 109.261 84.501  1.00 37.92  ? 84  SER B CA  1 
ATOM 2409 C C   . SER B 2 94  ? 112.314 110.323 84.957  1.00 49.61  ? 84  SER B C   1 
ATOM 2410 O O   . SER B 2 94  ? 113.028 110.114 85.943  1.00 59.89  ? 84  SER B O   1 
ATOM 2411 C CB  . SER B 2 94  ? 112.032 108.204 83.658  1.00 47.29  ? 84  SER B CB  1 
ATOM 2412 O OG  . SER B 2 94  ? 112.509 108.756 82.448  1.00 51.78  ? 84  SER B OG  1 
ATOM 2413 N N   . TYR B 2 95  ? 112.393 111.450 84.246  1.00 47.57  ? 85  TYR B N   1 
ATOM 2414 C CA  . TYR B 2 95  ? 113.326 112.499 84.644  1.00 44.91  ? 85  TYR B CA  1 
ATOM 2415 C C   . TYR B 2 95  ? 112.913 113.141 85.962  1.00 40.84  ? 85  TYR B C   1 
ATOM 2416 O O   . TYR B 2 95  ? 113.763 113.425 86.813  1.00 46.90  ? 85  TYR B O   1 
ATOM 2417 C CB  . TYR B 2 95  ? 113.437 113.560 83.552  1.00 41.14  ? 85  TYR B CB  1 
ATOM 2418 C CG  . TYR B 2 95  ? 114.209 113.128 82.327  1.00 43.58  ? 85  TYR B CG  1 
ATOM 2419 C CD1 . TYR B 2 95  ? 114.623 111.817 82.166  1.00 45.25  ? 85  TYR B CD1 1 
ATOM 2420 C CD2 . TYR B 2 95  ? 114.541 114.042 81.341  1.00 47.35  ? 85  TYR B CD2 1 
ATOM 2421 C CE1 . TYR B 2 95  ? 115.329 111.426 81.052  1.00 49.07  ? 85  TYR B CE1 1 
ATOM 2422 C CE2 . TYR B 2 95  ? 115.248 113.660 80.225  1.00 46.18  ? 85  TYR B CE2 1 
ATOM 2423 C CZ  . TYR B 2 95  ? 115.639 112.351 80.085  1.00 47.91  ? 85  TYR B CZ  1 
ATOM 2424 O OH  . TYR B 2 95  ? 116.347 111.966 78.971  1.00 48.66  ? 85  TYR B OH  1 
ATOM 2425 N N   . THR B 2 96  ? 111.617 113.376 86.151  1.00 38.31  ? 86  THR B N   1 
ATOM 2426 C CA  . THR B 2 96  ? 111.122 114.077 87.324  1.00 43.72  ? 86  THR B CA  1 
ATOM 2427 C C   . THR B 2 96  ? 110.361 113.187 88.295  1.00 46.50  ? 86  THR B C   1 
ATOM 2428 O O   . THR B 2 96  ? 109.978 113.665 89.367  1.00 50.52  ? 86  THR B O   1 
ATOM 2429 C CB  . THR B 2 96  ? 110.218 115.243 86.902  1.00 43.39  ? 86  THR B CB  1 
ATOM 2430 O OG1 . THR B 2 96  ? 109.068 114.733 86.221  1.00 45.25  ? 86  THR B OG1 1 
ATOM 2431 C CG2 . THR B 2 96  ? 110.964 116.175 85.972  1.00 45.21  ? 86  THR B CG2 1 
ATOM 2432 N N   . THR B 2 97  ? 110.122 111.924 87.946  1.00 47.99  ? 87  THR B N   1 
ATOM 2433 C CA  . THR B 2 97  ? 109.252 110.995 88.665  1.00 39.94  ? 87  THR B CA  1 
ATOM 2434 C C   . THR B 2 97  ? 107.807 111.469 88.725  1.00 47.74  ? 87  THR B C   1 
ATOM 2435 O O   . THR B 2 97  ? 107.016 110.928 89.506  1.00 51.29  ? 87  THR B O   1 
ATOM 2436 C CB  . THR B 2 97  ? 109.761 110.697 90.081  1.00 43.51  ? 87  THR B CB  1 
ATOM 2437 O OG1 . THR B 2 97  ? 109.683 111.880 90.882  1.00 52.55  ? 87  THR B OG1 1 
ATOM 2438 C CG2 . THR B 2 97  ? 111.197 110.210 90.038  1.00 41.77  ? 87  THR B CG2 1 
ATOM 2439 N N   . ASN B 2 98  ? 107.445 112.477 87.938  1.00 43.79  ? 88  ASN B N   1 
ATOM 2440 C CA  . ASN B 2 98  ? 106.055 112.898 87.864  1.00 43.63  ? 88  ASN B CA  1 
ATOM 2441 C C   . ASN B 2 98  ? 105.223 111.827 87.176  1.00 45.75  ? 88  ASN B C   1 
ATOM 2442 O O   . ASN B 2 98  ? 105.675 111.179 86.230  1.00 47.18  ? 88  ASN B O   1 
ATOM 2443 C CB  . ASN B 2 98  ? 105.931 114.216 87.101  1.00 43.05  ? 88  ASN B CB  1 
ATOM 2444 C CG  . ASN B 2 98  ? 106.412 115.402 87.900  1.00 42.19  ? 88  ASN B CG  1 
ATOM 2445 O OD1 . ASN B 2 98  ? 106.277 115.440 89.119  1.00 48.67  ? 88  ASN B OD1 1 
ATOM 2446 N ND2 . ASN B 2 98  ? 106.983 116.381 87.214  1.00 46.35  ? 88  ASN B ND2 1 
ATOM 2447 N N   . LYS B 2 99  ? 104.001 111.640 87.655  1.00 34.70  ? 89  LYS B N   1 
ATOM 2448 C CA  . LYS B 2 99  ? 103.039 110.785 86.979  1.00 30.86  ? 89  LYS B CA  1 
ATOM 2449 C C   . LYS B 2 99  ? 102.314 111.601 85.920  1.00 35.79  ? 89  LYS B C   1 
ATOM 2450 O O   . LYS B 2 99  ? 101.639 112.584 86.241  1.00 46.48  ? 89  LYS B O   1 
ATOM 2451 C CB  . LYS B 2 99  ? 102.048 110.170 87.962  1.00 30.05  ? 89  LYS B CB  1 
ATOM 2452 C CG  . LYS B 2 99  ? 102.699 109.287 88.991  1.00 34.97  ? 89  LYS B CG  1 
ATOM 2453 C CD  . LYS B 2 99  ? 101.680 108.687 89.919  1.00 29.77  ? 89  LYS B CD  1 
ATOM 2454 C CE  . LYS B 2 99  ? 102.366 107.828 90.948  1.00 39.30  ? 89  LYS B CE  1 
ATOM 2455 N NZ  . LYS B 2 99  ? 103.295 108.631 91.782  1.00 38.42  ? 89  LYS B NZ  1 
ATOM 2456 N N   . VAL B 2 100 ? 102.467 111.202 84.660  1.00 27.80  ? 90  VAL B N   1 
ATOM 2457 C CA  . VAL B 2 100 ? 101.817 111.927 83.579  1.00 29.13  ? 90  VAL B CA  1 
ATOM 2458 C C   . VAL B 2 100 ? 100.366 111.495 83.449  1.00 25.68  ? 90  VAL B C   1 
ATOM 2459 O O   . VAL B 2 100 ? 99.472  112.330 83.280  1.00 31.68  ? 90  VAL B O   1 
ATOM 2460 C CB  . VAL B 2 100 ? 102.594 111.721 82.267  1.00 27.65  ? 90  VAL B CB  1 
ATOM 2461 C CG1 . VAL B 2 100 ? 101.940 112.482 81.140  1.00 32.49  ? 90  VAL B CG1 1 
ATOM 2462 C CG2 . VAL B 2 100 ? 104.031 112.168 82.432  1.00 27.34  ? 90  VAL B CG2 1 
ATOM 2463 N N   . HIS B 2 101 ? 100.104 110.195 83.554  1.00 48.43  ? 91  HIS B N   1 
ATOM 2464 C CA  . HIS B 2 101 ? 98.756  109.658 83.474  1.00 50.18  ? 91  HIS B CA  1 
ATOM 2465 C C   . HIS B 2 101 ? 98.609  108.522 84.473  1.00 51.45  ? 91  HIS B C   1 
ATOM 2466 O O   . HIS B 2 101 ? 99.589  107.908 84.895  1.00 55.93  ? 91  HIS B O   1 
ATOM 2467 C CB  . HIS B 2 101 ? 98.424  109.148 82.065  1.00 51.77  ? 91  HIS B CB  1 
ATOM 2468 C CG  . HIS B 2 101 ? 98.417  110.215 81.017  1.00 47.88  ? 91  HIS B CG  1 
ATOM 2469 N ND1 . HIS B 2 101 ? 97.406  111.144 80.907  1.00 45.56  ? 91  HIS B ND1 1 
ATOM 2470 C CD2 . HIS B 2 101 ? 99.294  110.494 80.024  1.00 48.68  ? 91  HIS B CD2 1 
ATOM 2471 C CE1 . HIS B 2 101 ? 97.663  111.953 79.896  1.00 52.02  ? 91  HIS B CE1 1 
ATOM 2472 N NE2 . HIS B 2 101 ? 98.802  111.580 79.343  1.00 45.35  ? 91  HIS B NE2 1 
ATOM 2473 N N   . ALA B 2 102 ? 97.362  108.253 84.849  1.00 52.02  ? 92  ALA B N   1 
ATOM 2474 C CA  . ALA B 2 102 ? 97.010  107.068 85.625  1.00 43.38  ? 92  ALA B CA  1 
ATOM 2475 C C   . ALA B 2 102 ? 95.756  106.489 84.994  1.00 50.71  ? 92  ALA B C   1 
ATOM 2476 O O   . ALA B 2 102 ? 94.671  107.063 85.124  1.00 63.14  ? 92  ALA B O   1 
ATOM 2477 C CB  . ALA B 2 102 ? 96.780  107.395 87.096  1.00 50.47  ? 92  ALA B CB  1 
ATOM 2478 N N   . ILE B 2 103 ? 95.903  105.355 84.317  1.00 45.24  ? 93  ILE B N   1 
ATOM 2479 C CA  . ILE B 2 103 ? 94.831  104.757 83.530  1.00 48.28  ? 93  ILE B CA  1 
ATOM 2480 C C   . ILE B 2 103 ? 94.205  103.639 84.361  1.00 45.89  ? 93  ILE B C   1 
ATOM 2481 O O   . ILE B 2 103 ? 94.884  102.639 84.639  1.00 49.13  ? 93  ILE B O   1 
ATOM 2482 C CB  . ILE B 2 103 ? 95.355  104.224 82.192  1.00 44.10  ? 93  ILE B CB  1 
ATOM 2483 C CG1 . ILE B 2 103 ? 96.208  105.289 81.501  1.00 38.84  ? 93  ILE B CG1 1 
ATOM 2484 C CG2 . ILE B 2 103 ? 94.206  103.790 81.313  1.00 44.55  ? 93  ILE B CG2 1 
ATOM 2485 C CD1 . ILE B 2 103 ? 96.998  104.771 80.336  1.00 46.89  ? 93  ILE B CD1 1 
ATOM 2486 N N   . PRO B 2 104 ? 92.949  103.764 84.782  1.00 41.26  ? 94  PRO B N   1 
ATOM 2487 C CA  . PRO B 2 104 ? 92.301  102.653 85.487  1.00 44.86  ? 94  PRO B CA  1 
ATOM 2488 C C   . PRO B 2 104 ? 91.925  101.550 84.509  1.00 53.55  ? 94  PRO B C   1 
ATOM 2489 O O   . PRO B 2 104 ? 91.264  101.795 83.498  1.00 55.23  ? 94  PRO B O   1 
ATOM 2490 C CB  . PRO B 2 104 ? 91.065  103.304 86.115  1.00 45.74  ? 94  PRO B CB  1 
ATOM 2491 C CG  . PRO B 2 104 ? 90.767  104.454 85.226  1.00 51.78  ? 94  PRO B CG  1 
ATOM 2492 C CD  . PRO B 2 104 ? 92.086  104.954 84.710  1.00 50.02  ? 94  PRO B CD  1 
ATOM 2493 N N   . LEU B 2 105 ? 92.354  100.331 84.814  1.00 47.43  ? 95  LEU B N   1 
ATOM 2494 C CA  . LEU B 2 105 ? 92.106  99.191  83.948  1.00 38.98  ? 95  LEU B CA  1 
ATOM 2495 C C   . LEU B 2 105 ? 90.779  98.544  84.314  1.00 49.48  ? 95  LEU B C   1 
ATOM 2496 O O   . LEU B 2 105 ? 90.438  98.422  85.493  1.00 51.13  ? 95  LEU B O   1 
ATOM 2497 C CB  . LEU B 2 105 ? 93.238  98.170  84.062  1.00 39.54  ? 95  LEU B CB  1 
ATOM 2498 C CG  . LEU B 2 105 ? 94.649  98.689  83.794  1.00 36.90  ? 95  LEU B CG  1 
ATOM 2499 C CD1 . LEU B 2 105 ? 95.650  97.555  83.823  1.00 39.99  ? 95  LEU B CD1 1 
ATOM 2500 C CD2 . LEU B 2 105 ? 94.711  99.428  82.473  1.00 36.74  ? 95  LEU B CD2 1 
ATOM 2501 N N   . ARG B 2 106 ? 90.024  98.142  83.289  1.00 52.73  ? 96  ARG B N   1 
ATOM 2502 C CA  . ARG B 2 106 ? 88.759  97.456  83.532  1.00 49.26  ? 96  ARG B CA  1 
ATOM 2503 C C   . ARG B 2 106 ? 88.985  96.119  84.223  1.00 49.96  ? 96  ARG B C   1 
ATOM 2504 O O   . ARG B 2 106 ? 88.223  95.737  85.118  1.00 55.92  ? 96  ARG B O   1 
ATOM 2505 C CB  . ARG B 2 106 ? 88.005  97.269  82.218  1.00 50.58  ? 96  ARG B CB  1 
ATOM 2506 C CG  . ARG B 2 106 ? 87.700  98.572  81.503  1.00 55.19  ? 96  ARG B CG  1 
ATOM 2507 C CD  . ARG B 2 106 ? 86.900  98.344  80.232  1.00 56.65  ? 96  ARG B CD  1 
ATOM 2508 N NE  . ARG B 2 106 ? 86.564  99.600  79.571  1.00 55.98  ? 96  ARG B NE  1 
ATOM 2509 C CZ  . ARG B 2 106 ? 85.842  99.693  78.463  1.00 54.40  ? 96  ARG B CZ  1 
ATOM 2510 N NH1 . ARG B 2 106 ? 85.359  98.620  77.860  1.00 53.73  ? 96  ARG B NH1 1 
ATOM 2511 N NH2 . ARG B 2 106 ? 85.594  100.894 77.950  1.00 52.14  ? 96  ARG B NH2 1 
ATOM 2512 N N   . SER B 2 107 ? 90.022  95.392  83.820  1.00 48.09  ? 97  SER B N   1 
ATOM 2513 C CA  . SER B 2 107 ? 90.426  94.155  84.472  1.00 46.74  ? 97  SER B CA  1 
ATOM 2514 C C   . SER B 2 107 ? 91.780  94.375  85.129  1.00 47.51  ? 97  SER B C   1 
ATOM 2515 O O   . SER B 2 107 ? 92.736  94.787  84.464  1.00 51.48  ? 97  SER B O   1 
ATOM 2516 C CB  . SER B 2 107 ? 90.494  93.001  83.472  1.00 47.95  ? 97  SER B CB  1 
ATOM 2517 O OG  . SER B 2 107 ? 90.864  91.796  84.114  1.00 51.93  ? 97  SER B OG  1 
ATOM 2518 N N   . SER B 2 108 ? 91.861  94.096  86.428  1.00 37.81  ? 98  SER B N   1 
ATOM 2519 C CA  . SER B 2 108 ? 93.072  94.369  87.189  1.00 44.01  ? 98  SER B CA  1 
ATOM 2520 C C   . SER B 2 108 ? 94.144  93.303  87.030  1.00 43.55  ? 98  SER B C   1 
ATOM 2521 O O   . SER B 2 108 ? 95.262  93.500  87.514  1.00 45.76  ? 98  SER B O   1 
ATOM 2522 C CB  . SER B 2 108 ? 92.735  94.525  88.672  1.00 48.30  ? 98  SER B CB  1 
ATOM 2523 O OG  . SER B 2 108 ? 92.164  93.340  89.193  1.00 56.06  ? 98  SER B OG  1 
ATOM 2524 N N   . TRP B 2 109 ? 93.846  92.188  86.377  1.00 43.93  ? 99  TRP B N   1 
ATOM 2525 C CA  . TRP B 2 109 ? 94.802  91.086  86.290  1.00 45.09  ? 99  TRP B CA  1 
ATOM 2526 C C   . TRP B 2 109 ? 95.723  91.230  85.089  1.00 44.34  ? 99  TRP B C   1 
ATOM 2527 O O   . TRP B 2 109 ? 95.911  90.303  84.310  1.00 53.95  ? 99  TRP B O   1 
ATOM 2528 C CB  . TRP B 2 109 ? 94.046  89.766  86.253  1.00 45.75  ? 99  TRP B CB  1 
ATOM 2529 C CG  . TRP B 2 109 ? 93.045  89.688  87.341  1.00 43.09  ? 99  TRP B CG  1 
ATOM 2530 C CD1 . TRP B 2 109 ? 91.705  89.884  87.236  1.00 41.57  ? 99  TRP B CD1 1 
ATOM 2531 C CD2 . TRP B 2 109 ? 93.308  89.431  88.721  1.00 39.08  ? 99  TRP B CD2 1 
ATOM 2532 N NE1 . TRP B 2 109 ? 91.111  89.751  88.464  1.00 44.44  ? 99  TRP B NE1 1 
ATOM 2533 C CE2 . TRP B 2 109 ? 92.077  89.472  89.393  1.00 45.67  ? 99  TRP B CE2 1 
ATOM 2534 C CE3 . TRP B 2 109 ? 94.467  89.162  89.452  1.00 40.01  ? 99  TRP B CE3 1 
ATOM 2535 C CZ2 . TRP B 2 109 ? 91.971  89.255  90.759  1.00 53.37  ? 99  TRP B CZ2 1 
ATOM 2536 C CZ3 . TRP B 2 109 ? 94.358  88.946  90.806  1.00 42.54  ? 99  TRP B CZ3 1 
ATOM 2537 C CH2 . TRP B 2 109 ? 93.120  88.993  91.447  1.00 46.92  ? 99  TRP B CH2 1 
ATOM 2538 N N   . VAL B 2 110 ? 96.333  92.398  84.961  1.00 45.61  ? 100 VAL B N   1 
ATOM 2539 C CA  . VAL B 2 110 ? 97.163  92.711  83.807  1.00 40.35  ? 100 VAL B CA  1 
ATOM 2540 C C   . VAL B 2 110 ? 98.510  92.018  83.953  1.00 42.10  ? 100 VAL B C   1 
ATOM 2541 O O   . VAL B 2 110 ? 99.076  91.938  85.049  1.00 43.12  ? 100 VAL B O   1 
ATOM 2542 C CB  . VAL B 2 110 ? 97.314  94.236  83.661  1.00 43.58  ? 100 VAL B CB  1 
ATOM 2543 C CG1 . VAL B 2 110 ? 97.932  94.834  84.909  1.00 37.39  ? 100 VAL B CG1 1 
ATOM 2544 C CG2 . VAL B 2 110 ? 98.125  94.588  82.433  1.00 47.96  ? 100 VAL B CG2 1 
ATOM 2545 N N   . MET B 2 111 ? 99.029  91.510  82.837  1.00 43.29  ? 101 MET B N   1 
ATOM 2546 C CA  . MET B 2 111 ? 100.307 90.821  82.811  1.00 33.16  ? 101 MET B CA  1 
ATOM 2547 C C   . MET B 2 111 ? 101.325 91.467  81.893  1.00 30.02  ? 101 MET B C   1 
ATOM 2548 O O   . MET B 2 111 ? 102.517 91.175  82.025  1.00 39.90  ? 101 MET B O   1 
ATOM 2549 C CB  . MET B 2 111 ? 100.124 89.354  82.390  1.00 41.12  ? 101 MET B CB  1 
ATOM 2550 C CG  . MET B 2 111 ? 99.335  88.523  83.386  1.00 44.71  ? 101 MET B CG  1 
ATOM 2551 S SD  . MET B 2 111 ? 99.190  86.798  82.898  1.00 64.51  ? 101 MET B SD  1 
ATOM 2552 C CE  . MET B 2 111 ? 100.914 86.335  82.785  1.00 42.44  ? 101 MET B CE  1 
ATOM 2553 N N   . THR B 2 112 ? 100.897 92.314  80.963  1.00 36.52  ? 102 THR B N   1 
ATOM 2554 C CA  . THR B 2 112 ? 101.804 92.941  80.018  1.00 40.53  ? 102 THR B CA  1 
ATOM 2555 C C   . THR B 2 112 ? 101.331 94.356  79.730  1.00 39.86  ? 102 THR B C   1 
ATOM 2556 O O   . THR B 2 112 ? 100.160 94.695  79.912  1.00 45.62  ? 102 THR B O   1 
ATOM 2557 C CB  . THR B 2 112 ? 101.899 92.149  78.711  1.00 46.09  ? 102 THR B CB  1 
ATOM 2558 O OG1 . THR B 2 112 ? 102.794 92.815  77.814  1.00 49.81  ? 102 THR B OG1 1 
ATOM 2559 C CG2 . THR B 2 112 ? 100.533 92.030  78.062  1.00 29.67  ? 102 THR B CG2 1 
ATOM 2560 N N   . CYS B 2 113 ? 102.271 95.187  79.287  1.00 32.47  ? 103 CYS B N   1 
ATOM 2561 C CA  . CYS B 2 113 ? 101.959 96.528  78.825  1.00 25.67  ? 103 CYS B CA  1 
ATOM 2562 C C   . CYS B 2 113 ? 102.973 96.908  77.760  1.00 37.26  ? 103 CYS B C   1 
ATOM 2563 O O   . CYS B 2 113 ? 104.114 96.442  77.778  1.00 39.85  ? 103 CYS B O   1 
ATOM 2564 C CB  . CYS B 2 113 ? 101.958 97.553  79.966  1.00 13.83  ? 103 CYS B CB  1 
ATOM 2565 S SG  . CYS B 2 113 ? 103.559 97.864  80.717  1.00 31.10  ? 103 CYS B SG  1 
ATOM 2566 N N   . ALA B 2 114 ? 102.541 97.744  76.821  1.00 33.11  ? 104 ALA B N   1 
ATOM 2567 C CA  . ALA B 2 114 ? 103.398 98.193  75.738  1.00 25.98  ? 104 ALA B CA  1 
ATOM 2568 C C   . ALA B 2 114 ? 103.165 99.671  75.479  1.00 32.55  ? 104 ALA B C   1 
ATOM 2569 O O   . ALA B 2 114 ? 102.040 100.161 75.590  1.00 40.34  ? 104 ALA B O   1 
ATOM 2570 C CB  . ALA B 2 114 ? 103.150 97.393  74.455  1.00 21.73  ? 104 ALA B CB  1 
ATOM 2571 N N   . TYR B 2 115 ? 104.241 100.375 75.152  1.00 37.82  ? 105 TYR B N   1 
ATOM 2572 C CA  . TYR B 2 115 ? 104.196 101.769 74.740  1.00 23.92  ? 105 TYR B CA  1 
ATOM 2573 C C   . TYR B 2 115 ? 104.408 101.849 73.235  1.00 36.33  ? 105 TYR B C   1 
ATOM 2574 O O   . TYR B 2 115 ? 105.385 101.302 72.715  1.00 39.03  ? 105 TYR B O   1 
ATOM 2575 C CB  . TYR B 2 115 ? 105.265 102.579 75.473  1.00 26.14  ? 105 TYR B CB  1 
ATOM 2576 C CG  . TYR B 2 115 ? 104.860 103.989 75.822  1.00 34.42  ? 105 TYR B CG  1 
ATOM 2577 C CD1 . TYR B 2 115 ? 103.960 104.690 75.037  1.00 37.08  ? 105 TYR B CD1 1 
ATOM 2578 C CD2 . TYR B 2 115 ? 105.375 104.616 76.946  1.00 29.13  ? 105 TYR B CD2 1 
ATOM 2579 C CE1 . TYR B 2 115 ? 103.591 105.975 75.359  1.00 38.15  ? 105 TYR B CE1 1 
ATOM 2580 C CE2 . TYR B 2 115 ? 105.010 105.899 77.273  1.00 23.11  ? 105 TYR B CE2 1 
ATOM 2581 C CZ  . TYR B 2 115 ? 104.119 106.575 76.478  1.00 34.83  ? 105 TYR B CZ  1 
ATOM 2582 O OH  . TYR B 2 115 ? 103.753 107.857 76.804  1.00 50.21  ? 105 TYR B OH  1 
ATOM 2583 N N   . ALA B 2 116 ? 103.497 102.521 72.540  1.00 35.37  ? 106 ALA B N   1 
ATOM 2584 C CA  . ALA B 2 116 ? 103.625 102.661 71.099  1.00 17.63  ? 106 ALA B CA  1 
ATOM 2585 C C   . ALA B 2 116 ? 104.854 103.501 70.764  1.00 34.40  ? 106 ALA B C   1 
ATOM 2586 O O   . ALA B 2 116 ? 105.175 104.446 71.489  1.00 46.74  ? 106 ALA B O   1 
ATOM 2587 C CB  . ALA B 2 116 ? 102.379 103.307 70.503  1.00 20.86  ? 106 ALA B CB  1 
ATOM 2588 N N   . PRO B 2 117 ? 105.565 103.178 69.682  1.00 41.67  ? 107 PRO B N   1 
ATOM 2589 C CA  . PRO B 2 117 ? 106.740 103.985 69.320  1.00 38.21  ? 107 PRO B CA  1 
ATOM 2590 C C   . PRO B 2 117 ? 106.414 105.437 69.035  1.00 42.35  ? 107 PRO B C   1 
ATOM 2591 O O   . PRO B 2 117 ? 107.273 106.304 69.234  1.00 41.26  ? 107 PRO B O   1 
ATOM 2592 C CB  . PRO B 2 117 ? 107.281 103.269 68.076  1.00 39.48  ? 107 PRO B CB  1 
ATOM 2593 C CG  . PRO B 2 117 ? 106.115 102.521 67.531  1.00 34.73  ? 107 PRO B CG  1 
ATOM 2594 C CD  . PRO B 2 117 ? 105.321 102.094 68.716  1.00 43.12  ? 107 PRO B CD  1 
ATOM 2595 N N   . SER B 2 118 ? 105.199 105.735 68.575  1.00 46.04  ? 108 SER B N   1 
ATOM 2596 C CA  . SER B 2 118 ? 104.799 107.121 68.385  1.00 38.44  ? 108 SER B CA  1 
ATOM 2597 C C   . SER B 2 118 ? 104.521 107.832 69.700  1.00 44.89  ? 108 SER B C   1 
ATOM 2598 O O   . SER B 2 118 ? 104.608 109.062 69.755  1.00 51.38  ? 108 SER B O   1 
ATOM 2599 C CB  . SER B 2 118 ? 103.559 107.194 67.498  1.00 35.80  ? 108 SER B CB  1 
ATOM 2600 O OG  . SER B 2 118 ? 102.457 106.563 68.125  1.00 44.54  ? 108 SER B OG  1 
ATOM 2601 N N   . GLY B 2 119 ? 104.210 107.092 70.760  1.00 38.79  ? 109 GLY B N   1 
ATOM 2602 C CA  . GLY B 2 119 ? 103.860 107.693 72.024  1.00 30.47  ? 109 GLY B CA  1 
ATOM 2603 C C   . GLY B 2 119 ? 102.399 108.047 72.171  1.00 40.51  ? 109 GLY B C   1 
ATOM 2604 O O   . GLY B 2 119 ? 102.013 108.593 73.211  1.00 43.29  ? 109 GLY B O   1 
ATOM 2605 N N   . ASN B 2 120 ? 101.574 107.756 71.169  1.00 29.60  ? 110 ASN B N   1 
ATOM 2606 C CA  . ASN B 2 120 ? 100.166 108.116 71.204  1.00 25.88  ? 110 ASN B CA  1 
ATOM 2607 C C   . ASN B 2 120 ? 99.293  107.044 71.832  1.00 37.46  ? 110 ASN B C   1 
ATOM 2608 O O   . ASN B 2 120 ? 98.141  107.331 72.170  1.00 50.63  ? 110 ASN B O   1 
ATOM 2609 C CB  . ASN B 2 120 ? 99.650  108.402 69.790  1.00 36.31  ? 110 ASN B CB  1 
ATOM 2610 C CG  . ASN B 2 120 ? 100.513 109.392 69.041  1.00 39.12  ? 110 ASN B CG  1 
ATOM 2611 O OD1 . ASN B 2 120 ? 101.141 110.265 69.637  1.00 44.62  ? 110 ASN B OD1 1 
ATOM 2612 N ND2 . ASN B 2 120 ? 100.549 109.261 67.723  1.00 29.97  ? 110 ASN B ND2 1 
ATOM 2613 N N   . TYR B 2 121 ? 99.802  105.826 72.000  1.00 40.45  ? 111 TYR B N   1 
ATOM 2614 C CA  . TYR B 2 121 ? 98.990  104.721 72.482  1.00 29.35  ? 111 TYR B CA  1 
ATOM 2615 C C   . TYR B 2 121 ? 99.776  103.891 73.482  1.00 31.80  ? 111 TYR B C   1 
ATOM 2616 O O   . TYR B 2 121 ? 101.004 103.813 73.423  1.00 30.51  ? 111 TYR B O   1 
ATOM 2617 C CB  . TYR B 2 121 ? 98.516  103.822 71.333  1.00 27.81  ? 111 TYR B CB  1 
ATOM 2618 C CG  . TYR B 2 121 ? 97.657  104.535 70.321  1.00 37.08  ? 111 TYR B CG  1 
ATOM 2619 C CD1 . TYR B 2 121 ? 96.290  104.658 70.510  1.00 33.15  ? 111 TYR B CD1 1 
ATOM 2620 C CD2 . TYR B 2 121 ? 98.211  105.085 69.179  1.00 35.67  ? 111 TYR B CD2 1 
ATOM 2621 C CE1 . TYR B 2 121 ? 95.502  105.308 69.591  1.00 33.25  ? 111 TYR B CE1 1 
ATOM 2622 C CE2 . TYR B 2 121 ? 97.432  105.740 68.256  1.00 37.57  ? 111 TYR B CE2 1 
ATOM 2623 C CZ  . TYR B 2 121 ? 96.079  105.848 68.466  1.00 42.56  ? 111 TYR B CZ  1 
ATOM 2624 O OH  . TYR B 2 121 ? 95.297  106.499 67.543  1.00 47.87  ? 111 TYR B OH  1 
ATOM 2625 N N   . VAL B 2 122 ? 99.044  103.263 74.400  1.00 33.11  ? 112 VAL B N   1 
ATOM 2626 C CA  . VAL B 2 122 ? 99.575  102.216 75.258  1.00 24.28  ? 112 VAL B CA  1 
ATOM 2627 C C   . VAL B 2 122 ? 98.618  101.037 75.188  1.00 28.50  ? 112 VAL B C   1 
ATOM 2628 O O   . VAL B 2 122 ? 97.430  101.183 74.900  1.00 34.26  ? 112 VAL B O   1 
ATOM 2629 C CB  . VAL B 2 122 ? 99.771  102.665 76.726  1.00 19.46  ? 112 VAL B CB  1 
ATOM 2630 C CG1 . VAL B 2 122 ? 100.868 103.701 76.833  1.00 29.27  ? 112 VAL B CG1 1 
ATOM 2631 C CG2 . VAL B 2 122 ? 98.479  103.197 77.299  1.00 33.19  ? 112 VAL B CG2 1 
ATOM 2632 N N   . ALA B 2 123 ? 99.154  99.857  75.467  1.00 36.61  ? 113 ALA B N   1 
ATOM 2633 C CA  . ALA B 2 123 ? 98.400  98.618  75.400  1.00 24.21  ? 113 ALA B CA  1 
ATOM 2634 C C   . ALA B 2 123 ? 98.653  97.822  76.665  1.00 39.89  ? 113 ALA B C   1 
ATOM 2635 O O   . ALA B 2 123 ? 99.701  97.959  77.299  1.00 47.44  ? 113 ALA B O   1 
ATOM 2636 C CB  . ALA B 2 123 ? 98.781  97.784  74.176  1.00 23.11  ? 113 ALA B CB  1 
ATOM 2637 N N   . CYS B 2 124 ? 97.677  97.004  77.040  1.00 47.09  ? 114 CYS B N   1 
ATOM 2638 C CA  . CYS B 2 124 ? 97.816  96.149  78.208  1.00 39.77  ? 114 CYS B CA  1 
ATOM 2639 C C   . CYS B 2 124 ? 96.831  94.999  78.082  1.00 44.72  ? 114 CYS B C   1 
ATOM 2640 O O   . CYS B 2 124 ? 95.913  95.025  77.261  1.00 51.95  ? 114 CYS B O   1 
ATOM 2641 C CB  . CYS B 2 124 ? 97.584  96.926  79.508  1.00 42.12  ? 114 CYS B CB  1 
ATOM 2642 S SG  . CYS B 2 124 ? 95.862  97.361  79.819  1.00 71.37  ? 114 CYS B SG  1 
ATOM 2643 N N   . GLY B 2 125 ? 97.034  93.986  78.914  1.00 45.27  ? 115 GLY B N   1 
ATOM 2644 C CA  . GLY B 2 125 ? 96.132  92.858  78.958  1.00 40.07  ? 115 GLY B CA  1 
ATOM 2645 C C   . GLY B 2 125 ? 96.634  91.753  79.856  1.00 43.84  ? 115 GLY B C   1 
ATOM 2646 O O   . GLY B 2 125 ? 97.839  91.625  80.081  1.00 52.50  ? 115 GLY B O   1 
ATOM 2647 N N   . GLY B 2 126 ? 95.717  90.957  80.387  1.00 40.84  ? 116 GLY B N   1 
ATOM 2648 C CA  . GLY B 2 126 ? 96.090  89.889  81.288  1.00 31.52  ? 116 GLY B CA  1 
ATOM 2649 C C   . GLY B 2 126 ? 95.193  88.676  81.203  1.00 36.42  ? 116 GLY B C   1 
ATOM 2650 O O   . GLY B 2 126 ? 94.949  88.138  80.120  1.00 48.35  ? 116 GLY B O   1 
ATOM 2651 N N   . LEU B 2 127 ? 94.698  88.238  82.361  1.00 36.51  ? 117 LEU B N   1 
ATOM 2652 C CA  . LEU B 2 127 ? 93.811  87.086  82.450  1.00 44.11  ? 117 LEU B CA  1 
ATOM 2653 C C   . LEU B 2 127 ? 92.461  87.316  81.789  1.00 40.43  ? 117 LEU B C   1 
ATOM 2654 O O   . LEU B 2 127 ? 91.696  86.358  81.646  1.00 46.58  ? 117 LEU B O   1 
ATOM 2655 C CB  . LEU B 2 127 ? 93.605  86.695  83.913  1.00 45.38  ? 117 LEU B CB  1 
ATOM 2656 C CG  . LEU B 2 127 ? 94.872  86.391  84.710  1.00 38.93  ? 117 LEU B CG  1 
ATOM 2657 C CD1 . LEU B 2 127 ? 94.523  85.927  86.104  1.00 36.84  ? 117 LEU B CD1 1 
ATOM 2658 C CD2 . LEU B 2 127 ? 95.702  85.350  83.998  1.00 42.75  ? 117 LEU B CD2 1 
ATOM 2659 N N   . ASP B 2 128 ? 92.146  88.542  81.385  1.00 44.89  ? 118 ASP B N   1 
ATOM 2660 C CA  . ASP B 2 128 ? 90.890  88.807  80.698  1.00 35.56  ? 118 ASP B CA  1 
ATOM 2661 C C   . ASP B 2 128 ? 90.933  88.456  79.218  1.00 39.25  ? 118 ASP B C   1 
ATOM 2662 O O   . ASP B 2 128 ? 89.915  88.615  78.539  1.00 48.03  ? 118 ASP B O   1 
ATOM 2663 C CB  . ASP B 2 128 ? 90.494  90.276  80.868  1.00 42.55  ? 118 ASP B CB  1 
ATOM 2664 C CG  . ASP B 2 128 ? 91.531  91.231  80.310  1.00 51.94  ? 118 ASP B CG  1 
ATOM 2665 O OD1 . ASP B 2 128 ? 92.720  90.861  80.261  1.00 50.42  ? 118 ASP B OD1 1 
ATOM 2666 O OD2 . ASP B 2 128 ? 91.161  92.360  79.930  1.00 51.30  ? 118 ASP B OD2 1 
ATOM 2667 N N   . ASN B 2 129 ? 92.077  87.998  78.707  1.00 34.31  ? 119 ASN B N   1 
ATOM 2668 C CA  . ASN B 2 129 ? 92.233  87.552  77.323  1.00 33.29  ? 119 ASN B CA  1 
ATOM 2669 C C   . ASN B 2 129 ? 92.019  88.678  76.321  1.00 46.56  ? 119 ASN B C   1 
ATOM 2670 O O   . ASN B 2 129 ? 91.722  88.422  75.151  1.00 48.50  ? 119 ASN B O   1 
ATOM 2671 C CB  . ASN B 2 129 ? 91.302  86.378  76.997  1.00 30.94  ? 119 ASN B CB  1 
ATOM 2672 C CG  . ASN B 2 129 ? 91.578  85.162  77.847  1.00 35.65  ? 119 ASN B CG  1 
ATOM 2673 O OD1 . ASN B 2 129 ? 92.272  85.240  78.855  1.00 50.12  ? 119 ASN B OD1 1 
ATOM 2674 N ND2 . ASN B 2 129 ? 91.032  84.024  77.442  1.00 42.73  ? 119 ASN B ND2 1 
ATOM 2675 N N   . ILE B 2 130 ? 92.183  89.924  76.751  1.00 46.48  ? 120 ILE B N   1 
ATOM 2676 C CA  . ILE B 2 130 ? 91.893  91.090  75.929  1.00 39.01  ? 120 ILE B CA  1 
ATOM 2677 C C   . ILE B 2 130 ? 93.133  91.967  75.915  1.00 41.22  ? 120 ILE B C   1 
ATOM 2678 O O   . ILE B 2 130 ? 93.787  92.146  76.947  1.00 49.55  ? 120 ILE B O   1 
ATOM 2679 C CB  . ILE B 2 130 ? 90.680  91.884  76.462  1.00 38.84  ? 120 ILE B CB  1 
ATOM 2680 C CG1 . ILE B 2 130 ? 89.446  90.994  76.569  1.00 34.29  ? 120 ILE B CG1 1 
ATOM 2681 C CG2 . ILE B 2 130 ? 90.375  93.063  75.569  1.00 41.15  ? 120 ILE B CG2 1 
ATOM 2682 C CD1 . ILE B 2 130 ? 89.015  90.397  75.266  1.00 42.98  ? 120 ILE B CD1 1 
ATOM 2683 N N   . CYS B 2 131 ? 93.463  92.505  74.746  1.00 29.34  ? 121 CYS B N   1 
ATOM 2684 C CA  . CYS B 2 131 ? 94.477  93.542  74.616  1.00 27.49  ? 121 CYS B CA  1 
ATOM 2685 C C   . CYS B 2 131 ? 93.760  94.868  74.406  1.00 33.85  ? 121 CYS B C   1 
ATOM 2686 O O   . CYS B 2 131 ? 93.139  95.086  73.362  1.00 43.31  ? 121 CYS B O   1 
ATOM 2687 C CB  . CYS B 2 131 ? 95.430  93.241  73.464  1.00 34.96  ? 121 CYS B CB  1 
ATOM 2688 S SG  . CYS B 2 131 ? 96.814  94.386  73.335  1.00 52.88  ? 121 CYS B SG  1 
ATOM 2689 N N   . SER B 2 132 ? 93.837  95.747  75.397  1.00 37.51  ? 122 SER B N   1 
ATOM 2690 C CA  . SER B 2 132 ? 93.148  97.027  75.354  1.00 35.69  ? 122 SER B CA  1 
ATOM 2691 C C   . SER B 2 132 ? 94.115  98.108  74.898  1.00 35.18  ? 122 SER B C   1 
ATOM 2692 O O   . SER B 2 132 ? 95.230  98.209  75.418  1.00 46.91  ? 122 SER B O   1 
ATOM 2693 C CB  . SER B 2 132 ? 92.558  97.379  76.719  1.00 34.03  ? 122 SER B CB  1 
ATOM 2694 O OG  . SER B 2 132 ? 91.609  96.411  77.122  1.00 33.18  ? 122 SER B OG  1 
ATOM 2695 N N   . ILE B 2 133 ? 93.687  98.904  73.926  1.00 36.85  ? 123 ILE B N   1 
ATOM 2696 C CA  . ILE B 2 133 ? 94.477  100.005 73.395  1.00 27.81  ? 123 ILE B CA  1 
ATOM 2697 C C   . ILE B 2 133 ? 93.923  101.296 73.970  1.00 23.87  ? 123 ILE B C   1 
ATOM 2698 O O   . ILE B 2 133 ? 92.713  101.541 73.910  1.00 38.06  ? 123 ILE B O   1 
ATOM 2699 C CB  . ILE B 2 133 ? 94.444  100.028 71.858  1.00 29.98  ? 123 ILE B CB  1 
ATOM 2700 C CG1 . ILE B 2 133 ? 94.800  98.653  71.293  1.00 31.16  ? 123 ILE B CG1 1 
ATOM 2701 C CG2 . ILE B 2 133 ? 95.397  101.078 71.324  1.00 24.24  ? 123 ILE B CG2 1 
ATOM 2702 C CD1 . ILE B 2 133 ? 96.182  98.192  71.649  1.00 28.80  ? 123 ILE B CD1 1 
ATOM 2703 N N   . TYR B 2 134 ? 94.800  102.124 74.525  1.00 33.68  ? 124 TYR B N   1 
ATOM 2704 C CA  . TYR B 2 134 ? 94.410  103.371 75.164  1.00 28.42  ? 124 TYR B CA  1 
ATOM 2705 C C   . TYR B 2 134 ? 94.992  104.539 74.389  1.00 40.98  ? 124 TYR B C   1 
ATOM 2706 O O   . TYR B 2 134 ? 96.183  104.542 74.064  1.00 45.22  ? 124 TYR B O   1 
ATOM 2707 C CB  . TYR B 2 134 ? 94.881  103.417 76.618  1.00 33.17  ? 124 TYR B CB  1 
ATOM 2708 C CG  . TYR B 2 134 ? 94.253  102.364 77.491  1.00 32.11  ? 124 TYR B CG  1 
ATOM 2709 C CD1 . TYR B 2 134 ? 93.055  102.603 78.140  1.00 35.07  ? 124 TYR B CD1 1 
ATOM 2710 C CD2 . TYR B 2 134 ? 94.855  101.129 77.664  1.00 27.26  ? 124 TYR B CD2 1 
ATOM 2711 C CE1 . TYR B 2 134 ? 92.477  101.646 78.938  1.00 38.90  ? 124 TYR B CE1 1 
ATOM 2712 C CE2 . TYR B 2 134 ? 94.282  100.164 78.456  1.00 32.98  ? 124 TYR B CE2 1 
ATOM 2713 C CZ  . TYR B 2 134 ? 93.093  100.428 79.093  1.00 41.15  ? 124 TYR B CZ  1 
ATOM 2714 O OH  . TYR B 2 134 ? 92.515  99.469  79.889  1.00 49.34  ? 124 TYR B OH  1 
ATOM 2715 N N   . ASN B 2 135 ? 94.150  105.521 74.090  1.00 39.90  ? 125 ASN B N   1 
ATOM 2716 C CA  . ASN B 2 135 ? 94.570  106.716 73.374  1.00 41.37  ? 125 ASN B CA  1 
ATOM 2717 C C   . ASN B 2 135 ? 95.043  107.757 74.380  1.00 37.81  ? 125 ASN B C   1 
ATOM 2718 O O   . ASN B 2 135 ? 94.276  108.176 75.252  1.00 47.14  ? 125 ASN B O   1 
ATOM 2719 C CB  . ASN B 2 135 ? 93.425  107.262 72.523  1.00 41.99  ? 125 ASN B CB  1 
ATOM 2720 C CG  . ASN B 2 135 ? 93.887  108.293 71.522  1.00 47.20  ? 125 ASN B CG  1 
ATOM 2721 O OD1 . ASN B 2 135 ? 95.080  108.429 71.259  1.00 45.94  ? 125 ASN B OD1 1 
ATOM 2722 N ND2 . ASN B 2 135 ? 92.943  109.028 70.955  1.00 44.20  ? 125 ASN B ND2 1 
ATOM 2723 N N   . LEU B 2 136 ? 96.301  108.168 74.260  1.00 31.89  ? 126 LEU B N   1 
ATOM 2724 C CA  . LEU B 2 136 ? 96.886  109.130 75.183  1.00 30.88  ? 126 LEU B CA  1 
ATOM 2725 C C   . LEU B 2 136 ? 96.694  110.574 74.747  1.00 44.19  ? 126 LEU B C   1 
ATOM 2726 O O   . LEU B 2 136 ? 96.807  111.476 75.584  1.00 44.56  ? 126 LEU B O   1 
ATOM 2727 C CB  . LEU B 2 136 ? 98.381  108.852 75.361  1.00 32.36  ? 126 LEU B CB  1 
ATOM 2728 C CG  . LEU B 2 136 ? 98.752  107.430 75.772  1.00 32.58  ? 126 LEU B CG  1 
ATOM 2729 C CD1 . LEU B 2 136 ? 100.251 107.288 75.886  1.00 30.18  ? 126 LEU B CD1 1 
ATOM 2730 C CD2 . LEU B 2 136 ? 98.083  107.071 77.078  1.00 24.38  ? 126 LEU B CD2 1 
ATOM 2731 N N   . LYS B 2 137 ? 96.400  110.814 73.472  1.00 43.27  ? 127 LYS B N   1 
ATOM 2732 C CA  . LYS B 2 137 ? 96.290  112.158 72.912  1.00 34.78  ? 127 LYS B CA  1 
ATOM 2733 C C   . LYS B 2 137 ? 94.850  112.356 72.455  1.00 35.62  ? 127 LYS B C   1 
ATOM 2734 O O   . LYS B 2 137 ? 94.520  112.116 71.292  1.00 42.93  ? 127 LYS B O   1 
ATOM 2735 C CB  . LYS B 2 137 ? 97.260  112.343 71.754  1.00 34.76  ? 127 LYS B CB  1 
ATOM 2736 C CG  . LYS B 2 137 ? 98.654  111.797 71.992  1.00 35.44  ? 127 LYS B CG  1 
ATOM 2737 C CD  . LYS B 2 137 ? 99.389  112.581 73.052  1.00 41.86  ? 127 LYS B CD  1 
ATOM 2738 C CE  . LYS B 2 137 ? 100.831 112.130 73.148  1.00 40.05  ? 127 LYS B CE  1 
ATOM 2739 N NZ  . LYS B 2 137 ? 101.550 112.315 71.859  1.00 37.58  ? 127 LYS B NZ  1 
ATOM 2740 N N   . THR B 2 138 ? 93.994  112.803 73.368  1.00 44.24  ? 128 THR B N   1 
ATOM 2741 C CA  . THR B 2 138 ? 92.604  113.095 73.059  1.00 49.83  ? 128 THR B CA  1 
ATOM 2742 C C   . THR B 2 138 ? 92.299  114.561 73.335  1.00 51.90  ? 128 THR B C   1 
ATOM 2743 O O   . THR B 2 138 ? 92.910  115.186 74.206  1.00 56.98  ? 128 THR B O   1 
ATOM 2744 C CB  . THR B 2 138 ? 91.657  112.211 73.879  1.00 52.18  ? 128 THR B CB  1 
ATOM 2745 O OG1 . THR B 2 138 ? 91.794  112.526 75.269  1.00 49.07  ? 128 THR B OG1 1 
ATOM 2746 C CG2 . THR B 2 138 ? 91.987  110.749 73.676  1.00 50.36  ? 128 THR B CG2 1 
ATOM 2747 N N   . ARG B 2 139 ? 91.344  115.108 72.577  1.00 54.36  ? 129 ARG B N   1 
ATOM 2748 C CA  . ARG B 2 139 ? 90.891  116.474 72.815  1.00 55.69  ? 129 ARG B CA  1 
ATOM 2749 C C   . ARG B 2 139 ? 90.162  116.626 74.142  1.00 55.80  ? 129 ARG B C   1 
ATOM 2750 O O   . ARG B 2 139 ? 90.036  117.749 74.639  1.00 57.92  ? 129 ARG B O   1 
ATOM 2751 C CB  . ARG B 2 139 ? 89.976  116.939 71.684  1.00 58.91  ? 129 ARG B CB  1 
ATOM 2752 C CG  . ARG B 2 139 ? 90.682  117.207 70.373  1.00 61.66  ? 129 ARG B CG  1 
ATOM 2753 C CD  . ARG B 2 139 ? 89.928  118.258 69.581  1.00 61.32  ? 129 ARG B CD  1 
ATOM 2754 N NE  . ARG B 2 139 ? 89.851  119.518 70.310  1.00 66.65  ? 129 ARG B NE  1 
ATOM 2755 C CZ  . ARG B 2 139 ? 89.142  120.570 69.923  1.00 68.34  ? 129 ARG B CZ  1 
ATOM 2756 N NH1 . ARG B 2 139 ? 88.420  120.547 68.815  1.00 62.62  ? 129 ARG B NH1 1 
ATOM 2757 N NH2 . ARG B 2 139 ? 89.156  121.671 70.668  1.00 62.21  ? 129 ARG B NH2 1 
ATOM 2758 N N   . GLU B 2 140 ? 89.675  115.530 74.719  1.00 44.80  ? 130 GLU B N   1 
ATOM 2759 C CA  . GLU B 2 140 ? 88.955  115.581 75.983  1.00 45.18  ? 130 GLU B CA  1 
ATOM 2760 C C   . GLU B 2 140 ? 89.879  115.651 77.189  1.00 48.61  ? 130 GLU B C   1 
ATOM 2761 O O   . GLU B 2 140 ? 89.399  115.900 78.299  1.00 49.25  ? 130 GLU B O   1 
ATOM 2762 C CB  . GLU B 2 140 ? 88.026  114.373 76.109  1.00 38.26  ? 130 GLU B CB  1 
ATOM 2763 C CG  . GLU B 2 140 ? 86.840  114.400 75.159  1.00 47.95  ? 130 GLU B CG  1 
ATOM 2764 C CD  . GLU B 2 140 ? 87.222  114.094 73.725  1.00 60.14  ? 130 GLU B CD  1 
ATOM 2765 O OE1 . GLU B 2 140 ? 88.137  113.273 73.516  1.00 60.31  ? 130 GLU B OE1 1 
ATOM 2766 O OE2 . GLU B 2 140 ? 86.615  114.681 72.805  1.00 55.59  ? 130 GLU B OE2 1 
ATOM 2767 N N   . GLY B 2 141 ? 91.176  115.425 77.006  1.00 43.83  ? 131 GLY B N   1 
ATOM 2768 C CA  . GLY B 2 141 ? 92.131  115.560 78.084  1.00 44.49  ? 131 GLY B CA  1 
ATOM 2769 C C   . GLY B 2 141 ? 92.282  114.352 78.975  1.00 50.94  ? 131 GLY B C   1 
ATOM 2770 O O   . GLY B 2 141 ? 92.996  114.432 79.980  1.00 56.07  ? 131 GLY B O   1 
ATOM 2771 N N   . ASN B 2 142 ? 91.635  113.238 78.649  1.00 49.32  ? 132 ASN B N   1 
ATOM 2772 C CA  . ASN B 2 142 ? 91.740  112.019 79.432  1.00 42.64  ? 132 ASN B CA  1 
ATOM 2773 C C   . ASN B 2 142 ? 92.138  110.866 78.525  1.00 47.45  ? 132 ASN B C   1 
ATOM 2774 O O   . ASN B 2 142 ? 91.955  110.913 77.307  1.00 59.94  ? 132 ASN B O   1 
ATOM 2775 C CB  . ASN B 2 142 ? 90.425  111.685 80.152  1.00 46.11  ? 132 ASN B CB  1 
ATOM 2776 C CG  . ASN B 2 142 ? 89.230  111.666 79.216  1.00 50.68  ? 132 ASN B CG  1 
ATOM 2777 O OD1 . ASN B 2 142 ? 89.370  111.781 78.000  1.00 43.76  ? 132 ASN B OD1 1 
ATOM 2778 N ND2 . ASN B 2 142 ? 88.042  111.514 79.786  1.00 55.42  ? 132 ASN B ND2 1 
ATOM 2779 N N   . VAL B 2 143 ? 92.709  109.834 79.131  1.00 42.24  ? 133 VAL B N   1 
ATOM 2780 C CA  . VAL B 2 143 ? 93.027  108.615 78.401  1.00 46.65  ? 133 VAL B CA  1 
ATOM 2781 C C   . VAL B 2 143 ? 91.773  107.756 78.332  1.00 39.00  ? 133 VAL B C   1 
ATOM 2782 O O   . VAL B 2 143 ? 91.122  107.505 79.352  1.00 41.17  ? 133 VAL B O   1 
ATOM 2783 C CB  . VAL B 2 143 ? 94.184  107.863 79.072  1.00 37.10  ? 133 VAL B CB  1 
ATOM 2784 C CG1 . VAL B 2 143 ? 94.519  106.617 78.286  1.00 39.06  ? 133 VAL B CG1 1 
ATOM 2785 C CG2 . VAL B 2 143 ? 95.395  108.763 79.180  1.00 34.20  ? 133 VAL B CG2 1 
ATOM 2786 N N   . ARG B 2 144 ? 91.421  107.317 77.129  1.00 39.96  ? 134 ARG B N   1 
ATOM 2787 C CA  . ARG B 2 144 ? 90.253  106.476 76.929  1.00 50.28  ? 134 ARG B CA  1 
ATOM 2788 C C   . ARG B 2 144 ? 90.644  105.221 76.166  1.00 51.78  ? 134 ARG B C   1 
ATOM 2789 O O   . ARG B 2 144 ? 91.606  105.216 75.395  1.00 57.71  ? 134 ARG B O   1 
ATOM 2790 C CB  . ARG B 2 144 ? 89.147  107.224 76.182  1.00 54.00  ? 134 ARG B CB  1 
ATOM 2791 C CG  . ARG B 2 144 ? 89.601  107.883 74.902  1.00 52.99  ? 134 ARG B CG  1 
ATOM 2792 C CD  . ARG B 2 144 ? 88.459  108.638 74.255  1.00 56.90  ? 134 ARG B CD  1 
ATOM 2793 N NE  . ARG B 2 144 ? 88.899  109.388 73.087  1.00 65.95  ? 134 ARG B NE  1 
ATOM 2794 C CZ  . ARG B 2 144 ? 88.109  110.156 72.351  1.00 62.28  ? 134 ARG B CZ  1 
ATOM 2795 N NH1 . ARG B 2 144 ? 86.824  110.293 72.630  1.00 58.51  ? 134 ARG B NH1 1 
ATOM 2796 N NH2 . ARG B 2 144 ? 88.623  110.803 71.309  1.00 59.61  ? 134 ARG B NH2 1 
ATOM 2797 N N   . VAL B 2 145 ? 89.880  104.153 76.391  1.00 45.80  ? 135 VAL B N   1 
ATOM 2798 C CA  . VAL B 2 145 ? 90.051  102.930 75.618  1.00 45.76  ? 135 VAL B CA  1 
ATOM 2799 C C   . VAL B 2 145 ? 89.612  103.182 74.185  1.00 39.21  ? 135 VAL B C   1 
ATOM 2800 O O   . VAL B 2 145 ? 88.486  103.631 73.934  1.00 49.22  ? 135 VAL B O   1 
ATOM 2801 C CB  . VAL B 2 145 ? 89.257  101.775 76.245  1.00 41.72  ? 135 VAL B CB  1 
ATOM 2802 C CG1 . VAL B 2 145 ? 89.857  100.444 75.840  1.00 40.89  ? 135 VAL B CG1 1 
ATOM 2803 C CG2 . VAL B 2 145 ? 89.208  101.914 77.753  1.00 46.52  ? 135 VAL B CG2 1 
ATOM 2804 N N   . SER B 2 146 ? 90.499  102.900 73.235  1.00 37.69  ? 136 SER B N   1 
ATOM 2805 C CA  . SER B 2 146 ? 90.160  103.025 71.826  1.00 41.87  ? 136 SER B CA  1 
ATOM 2806 C C   . SER B 2 146 ? 89.800  101.699 71.178  1.00 46.82  ? 136 SER B C   1 
ATOM 2807 O O   . SER B 2 146 ? 88.978  101.679 70.258  1.00 53.49  ? 136 SER B O   1 
ATOM 2808 C CB  . SER B 2 146 ? 91.321  103.661 71.055  1.00 45.78  ? 136 SER B CB  1 
ATOM 2809 O OG  . SER B 2 146 ? 92.481  102.856 71.131  1.00 51.81  ? 136 SER B OG  1 
ATOM 2810 N N   . ARG B 2 147 ? 90.381  100.597 71.643  1.00 41.02  ? 137 ARG B N   1 
ATOM 2811 C CA  . ARG B 2 147 ? 90.107  99.280  71.090  1.00 41.48  ? 137 ARG B CA  1 
ATOM 2812 C C   . ARG B 2 147 ? 90.321  98.230  72.166  1.00 43.67  ? 137 ARG B C   1 
ATOM 2813 O O   . ARG B 2 147 ? 91.205  98.370  73.013  1.00 46.96  ? 137 ARG B O   1 
ATOM 2814 C CB  . ARG B 2 147 ? 91.003  98.967  69.889  1.00 51.25  ? 137 ARG B CB  1 
ATOM 2815 C CG  . ARG B 2 147 ? 90.514  99.535  68.576  1.00 54.24  ? 137 ARG B CG  1 
ATOM 2816 C CD  . ARG B 2 147 ? 89.166  98.960  68.191  1.00 47.80  ? 137 ARG B CD  1 
ATOM 2817 N NE  . ARG B 2 147 ? 88.678  99.527  66.941  1.00 57.06  ? 137 ARG B NE  1 
ATOM 2818 C CZ  . ARG B 2 147 ? 87.918  100.609 66.857  1.00 60.47  ? 137 ARG B CZ  1 
ATOM 2819 N NH1 . ARG B 2 147 ? 87.527  101.266 67.937  1.00 55.87  ? 137 ARG B NH1 1 
ATOM 2820 N NH2 . ARG B 2 147 ? 87.539  101.045 65.659  1.00 59.18  ? 137 ARG B NH2 1 
ATOM 2821 N N   . GLU B 2 148 ? 89.500  97.186  72.130  1.00 53.66  ? 138 GLU B N   1 
ATOM 2822 C CA  . GLU B 2 148 ? 89.705  95.978  72.920  1.00 47.94  ? 138 GLU B CA  1 
ATOM 2823 C C   . GLU B 2 148 ? 89.805  94.810  71.951  1.00 49.49  ? 138 GLU B C   1 
ATOM 2824 O O   . GLU B 2 148 ? 88.820  94.453  71.298  1.00 54.18  ? 138 GLU B O   1 
ATOM 2825 C CB  . GLU B 2 148 ? 88.577  95.781  73.927  1.00 47.89  ? 138 GLU B CB  1 
ATOM 2826 C CG  . GLU B 2 148 ? 88.476  96.910  74.928  1.00 48.88  ? 138 GLU B CG  1 
ATOM 2827 C CD  . GLU B 2 148 ? 87.457  96.643  76.007  1.00 56.04  ? 138 GLU B CD  1 
ATOM 2828 O OE1 . GLU B 2 148 ? 86.788  95.591  75.951  1.00 56.70  ? 138 GLU B OE1 1 
ATOM 2829 O OE2 . GLU B 2 148 ? 87.331  97.483  76.920  1.00 63.63  ? 138 GLU B OE2 1 
ATOM 2830 N N   . LEU B 2 149 ? 90.993  94.221  71.858  1.00 43.03  ? 139 LEU B N   1 
ATOM 2831 C CA  . LEU B 2 149 ? 91.276  93.171  70.883  1.00 40.15  ? 139 LEU B CA  1 
ATOM 2832 C C   . LEU B 2 149 ? 90.943  91.817  71.496  1.00 46.99  ? 139 LEU B C   1 
ATOM 2833 O O   . LEU B 2 149 ? 91.688  91.295  72.326  1.00 52.55  ? 139 LEU B O   1 
ATOM 2834 C CB  . LEU B 2 149 ? 92.730  93.244  70.440  1.00 40.22  ? 139 LEU B CB  1 
ATOM 2835 C CG  . LEU B 2 149 ? 93.165  94.619  69.936  1.00 40.78  ? 139 LEU B CG  1 
ATOM 2836 C CD1 . LEU B 2 149 ? 94.632  94.614  69.570  1.00 44.81  ? 139 LEU B CD1 1 
ATOM 2837 C CD2 . LEU B 2 149 ? 92.319  95.053  68.753  1.00 41.88  ? 139 LEU B CD2 1 
ATOM 2838 N N   . ALA B 2 150 ? 89.816  91.249  71.083  1.00 40.55  ? 140 ALA B N   1 
ATOM 2839 C CA  . ALA B 2 150 ? 89.370  89.940  71.533  1.00 39.35  ? 140 ALA B CA  1 
ATOM 2840 C C   . ALA B 2 150 ? 89.629  88.897  70.454  1.00 49.22  ? 140 ALA B C   1 
ATOM 2841 O O   . ALA B 2 150 ? 89.639  89.202  69.259  1.00 51.42  ? 140 ALA B O   1 
ATOM 2842 C CB  . ALA B 2 150 ? 87.883  89.963  71.884  1.00 36.63  ? 140 ALA B CB  1 
ATOM 2843 N N   . GLY B 2 151 ? 89.818  87.653  70.885  1.00 47.79  ? 141 GLY B N   1 
ATOM 2844 C CA  . GLY B 2 151 ? 90.135  86.584  69.961  1.00 47.26  ? 141 GLY B CA  1 
ATOM 2845 C C   . GLY B 2 151 ? 91.083  85.538  70.507  1.00 46.29  ? 141 GLY B C   1 
ATOM 2846 O O   . GLY B 2 151 ? 91.045  84.385  70.072  1.00 44.26  ? 141 GLY B O   1 
ATOM 2847 N N   . HIS B 2 152 ? 91.941  85.917  71.450  1.00 45.87  ? 142 HIS B N   1 
ATOM 2848 C CA  . HIS B 2 152 ? 92.762  84.929  72.134  1.00 38.71  ? 142 HIS B CA  1 
ATOM 2849 C C   . HIS B 2 152 ? 91.907  84.146  73.121  1.00 44.56  ? 142 HIS B C   1 
ATOM 2850 O O   . HIS B 2 152 ? 91.028  84.703  73.784  1.00 48.66  ? 142 HIS B O   1 
ATOM 2851 C CB  . HIS B 2 152 ? 93.923  85.601  72.863  1.00 33.64  ? 142 HIS B CB  1 
ATOM 2852 C CG  . HIS B 2 152 ? 95.050  86.013  71.968  1.00 43.23  ? 142 HIS B CG  1 
ATOM 2853 N ND1 . HIS B 2 152 ? 95.770  85.112  71.216  1.00 47.21  ? 142 HIS B ND1 1 
ATOM 2854 C CD2 . HIS B 2 152 ? 95.595  87.227  71.723  1.00 46.91  ? 142 HIS B CD2 1 
ATOM 2855 C CE1 . HIS B 2 152 ? 96.706  85.753  70.540  1.00 44.27  ? 142 HIS B CE1 1 
ATOM 2856 N NE2 . HIS B 2 152 ? 96.619  87.038  70.827  1.00 45.07  ? 142 HIS B NE2 1 
ATOM 2857 N N   . THR B 2 153 ? 92.167  82.845  73.221  1.00 30.65  ? 143 THR B N   1 
ATOM 2858 C CA  . THR B 2 153 ? 91.453  81.982  74.150  1.00 32.68  ? 143 THR B CA  1 
ATOM 2859 C C   . THR B 2 153 ? 92.254  81.686  75.410  1.00 37.83  ? 143 THR B C   1 
ATOM 2860 O O   . THR B 2 153 ? 91.862  80.816  76.193  1.00 39.70  ? 143 THR B O   1 
ATOM 2861 C CB  . THR B 2 153 ? 91.049  80.678  73.459  1.00 44.31  ? 143 THR B CB  1 
ATOM 2862 O OG1 . THR B 2 153 ? 92.178  80.124  72.775  1.00 48.26  ? 143 THR B OG1 1 
ATOM 2863 C CG2 . THR B 2 153 ? 89.939  80.936  72.458  1.00 39.13  ? 143 THR B CG2 1 
ATOM 2864 N N   . GLY B 2 154 ? 93.364  82.390  75.623  1.00 37.93  ? 144 GLY B N   1 
ATOM 2865 C CA  . GLY B 2 154 ? 94.131  82.280  76.845  1.00 30.51  ? 144 GLY B CA  1 
ATOM 2866 C C   . GLY B 2 154 ? 94.551  83.657  77.316  1.00 39.05  ? 144 GLY B C   1 
ATOM 2867 O O   . GLY B 2 154 ? 94.274  84.662  76.662  1.00 40.40  ? 144 GLY B O   1 
ATOM 2868 N N   . TYR B 2 155 ? 95.239  83.685  78.453  1.00 45.08  ? 145 TYR B N   1 
ATOM 2869 C CA  . TYR B 2 155 ? 95.659  84.956  79.021  1.00 36.13  ? 145 TYR B CA  1 
ATOM 2870 C C   . TYR B 2 155 ? 96.659  85.644  78.102  1.00 39.68  ? 145 TYR B C   1 
ATOM 2871 O O   . TYR B 2 155 ? 97.420  84.999  77.380  1.00 45.25  ? 145 TYR B O   1 
ATOM 2872 C CB  . TYR B 2 155 ? 96.269  84.750  80.408  1.00 28.65  ? 145 TYR B CB  1 
ATOM 2873 C CG  . TYR B 2 155 ? 97.527  83.916  80.415  1.00 42.46  ? 145 TYR B CG  1 
ATOM 2874 C CD1 . TYR B 2 155 ? 98.774  84.499  80.250  1.00 36.59  ? 145 TYR B CD1 1 
ATOM 2875 C CD2 . TYR B 2 155 ? 97.469  82.545  80.597  1.00 42.12  ? 145 TYR B CD2 1 
ATOM 2876 C CE1 . TYR B 2 155 ? 99.918  83.741  80.253  1.00 33.45  ? 145 TYR B CE1 1 
ATOM 2877 C CE2 . TYR B 2 155 ? 98.610  81.781  80.606  1.00 41.41  ? 145 TYR B CE2 1 
ATOM 2878 C CZ  . TYR B 2 155 ? 99.830  82.384  80.433  1.00 44.99  ? 145 TYR B CZ  1 
ATOM 2879 O OH  . TYR B 2 155 ? 100.971 81.622  80.439  1.00 55.82  ? 145 TYR B OH  1 
ATOM 2880 N N   . LEU B 2 156 ? 96.649  86.972  78.134  1.00 44.25  ? 146 LEU B N   1 
ATOM 2881 C CA  . LEU B 2 156 ? 97.583  87.758  77.342  1.00 35.60  ? 146 LEU B CA  1 
ATOM 2882 C C   . LEU B 2 156 ? 98.892  87.906  78.105  1.00 35.93  ? 146 LEU B C   1 
ATOM 2883 O O   . LEU B 2 156 ? 98.916  88.475  79.201  1.00 36.92  ? 146 LEU B O   1 
ATOM 2884 C CB  . LEU B 2 156 ? 96.992  89.127  77.025  1.00 36.99  ? 146 LEU B CB  1 
ATOM 2885 C CG  . LEU B 2 156 ? 97.614  89.828  75.822  1.00 43.25  ? 146 LEU B CG  1 
ATOM 2886 C CD1 . LEU B 2 156 ? 97.100  89.206  74.540  1.00 36.39  ? 146 LEU B CD1 1 
ATOM 2887 C CD2 . LEU B 2 156 ? 97.350  91.315  75.861  1.00 46.13  ? 146 LEU B CD2 1 
ATOM 2888 N N   . SER B 2 157 ? 99.979  87.407  77.524  1.00 29.93  ? 147 SER B N   1 
ATOM 2889 C CA  . SER B 2 157 ? 101.272 87.420  78.191  1.00 33.33  ? 147 SER B CA  1 
ATOM 2890 C C   . SER B 2 157 ? 102.195 88.531  77.715  1.00 36.87  ? 147 SER B C   1 
ATOM 2891 O O   . SER B 2 157 ? 102.987 89.039  78.514  1.00 48.05  ? 147 SER B O   1 
ATOM 2892 C CB  . SER B 2 157 ? 101.968 86.068  78.015  1.00 32.67  ? 147 SER B CB  1 
ATOM 2893 O OG  . SER B 2 157 ? 102.049 85.712  76.650  1.00 40.13  ? 147 SER B OG  1 
ATOM 2894 N N   . CYS B 2 158 ? 102.121 88.926  76.447  1.00 39.78  ? 148 CYS B N   1 
ATOM 2895 C CA  . CYS B 2 158 ? 102.971 89.998  75.951  1.00 36.40  ? 148 CYS B CA  1 
ATOM 2896 C C   . CYS B 2 158 ? 102.319 90.639  74.735  1.00 42.32  ? 148 CYS B C   1 
ATOM 2897 O O   . CYS B 2 158 ? 101.512 90.014  74.045  1.00 35.36  ? 148 CYS B O   1 
ATOM 2898 C CB  . CYS B 2 158 ? 104.372 89.488  75.599  1.00 32.99  ? 148 CYS B CB  1 
ATOM 2899 S SG  . CYS B 2 158 ? 105.527 90.766  75.057  1.00 39.11  ? 148 CYS B SG  1 
ATOM 2900 N N   . CYS B 2 159 ? 102.665 91.902  74.500  1.00 39.89  ? 149 CYS B N   1 
ATOM 2901 C CA  . CYS B 2 159 ? 102.168 92.653  73.357  1.00 29.20  ? 149 CYS B CA  1 
ATOM 2902 C C   . CYS B 2 159 ? 103.211 93.690  72.967  1.00 39.04  ? 149 CYS B C   1 
ATOM 2903 O O   . CYS B 2 159 ? 103.890 94.247  73.832  1.00 42.12  ? 149 CYS B O   1 
ATOM 2904 C CB  . CYS B 2 159 ? 100.823 93.324  73.658  1.00 30.63  ? 149 CYS B CB  1 
ATOM 2905 S SG  . CYS B 2 159 ? 100.823 94.453  75.060  1.00 54.99  ? 149 CYS B SG  1 
ATOM 2906 N N   . ARG B 2 160 ? 103.338 93.938  71.665  1.00 36.46  ? 150 ARG B N   1 
ATOM 2907 C CA  . ARG B 2 160 ? 104.292 94.912  71.148  1.00 28.74  ? 150 ARG B CA  1 
ATOM 2908 C C   . ARG B 2 160 ? 103.705 95.592  69.924  1.00 38.38  ? 150 ARG B C   1 
ATOM 2909 O O   . ARG B 2 160 ? 103.247 94.917  69.000  1.00 47.62  ? 150 ARG B O   1 
ATOM 2910 C CB  . ARG B 2 160 ? 105.623 94.248  70.789  1.00 32.01  ? 150 ARG B CB  1 
ATOM 2911 C CG  . ARG B 2 160 ? 106.509 93.950  71.977  1.00 37.89  ? 150 ARG B CG  1 
ATOM 2912 C CD  . ARG B 2 160 ? 106.925 95.231  72.670  1.00 33.42  ? 150 ARG B CD  1 
ATOM 2913 N NE  . ARG B 2 160 ? 107.593 94.976  73.939  1.00 31.22  ? 150 ARG B NE  1 
ATOM 2914 C CZ  . ARG B 2 160 ? 106.982 94.955  75.114  1.00 36.15  ? 150 ARG B CZ  1 
ATOM 2915 N NH1 . ARG B 2 160 ? 105.684 95.178  75.221  1.00 46.42  ? 150 ARG B NH1 1 
ATOM 2916 N NH2 . ARG B 2 160 ? 107.691 94.707  76.209  1.00 37.76  ? 150 ARG B NH2 1 
ATOM 2917 N N   . PHE B 2 161 ? 103.743 96.922  69.913  1.00 41.44  ? 151 PHE B N   1 
ATOM 2918 C CA  . PHE B 2 161 ? 103.291 97.683  68.758  1.00 28.34  ? 151 PHE B CA  1 
ATOM 2919 C C   . PHE B 2 161 ? 104.284 97.585  67.610  1.00 38.58  ? 151 PHE B C   1 
ATOM 2920 O O   . PHE B 2 161 ? 105.499 97.640  67.810  1.00 45.93  ? 151 PHE B O   1 
ATOM 2921 C CB  . PHE B 2 161 ? 103.103 99.155  69.124  1.00 24.51  ? 151 PHE B CB  1 
ATOM 2922 C CG  . PHE B 2 161 ? 101.852 99.446  69.898  1.00 38.15  ? 151 PHE B CG  1 
ATOM 2923 C CD1 . PHE B 2 161 ? 100.662 99.688  69.245  1.00 34.27  ? 151 PHE B CD1 1 
ATOM 2924 C CD2 . PHE B 2 161 ? 101.873 99.506  71.277  1.00 42.18  ? 151 PHE B CD2 1 
ATOM 2925 C CE1 . PHE B 2 161 ? 99.519  99.970  69.952  1.00 31.96  ? 151 PHE B CE1 1 
ATOM 2926 C CE2 . PHE B 2 161 ? 100.734 99.784  71.985  1.00 24.93  ? 151 PHE B CE2 1 
ATOM 2927 C CZ  . PHE B 2 161 ? 99.556  100.018 71.325  1.00 23.39  ? 151 PHE B CZ  1 
ATOM 2928 N N   . LEU B 2 162 ? 103.758 97.433  66.397  1.00 39.49  ? 152 LEU B N   1 
ATOM 2929 C CA  . LEU B 2 162 ? 104.547 97.678  65.197  1.00 43.13  ? 152 LEU B CA  1 
ATOM 2930 C C   . LEU B 2 162 ? 104.418 99.125  64.743  1.00 44.63  ? 152 LEU B C   1 
ATOM 2931 O O   . LEU B 2 162 ? 105.401 99.732  64.309  1.00 41.97  ? 152 LEU B O   1 
ATOM 2932 C CB  . LEU B 2 162 ? 104.124 96.736  64.067  1.00 42.75  ? 152 LEU B CB  1 
ATOM 2933 C CG  . LEU B 2 162 ? 104.693 95.316  64.077  1.00 46.13  ? 152 LEU B CG  1 
ATOM 2934 C CD1 . LEU B 2 162 ? 104.071 94.484  65.175  1.00 45.15  ? 152 LEU B CD1 1 
ATOM 2935 C CD2 . LEU B 2 162 ? 104.493 94.658  62.727  1.00 48.43  ? 152 LEU B CD2 1 
ATOM 2936 N N   . ASP B 2 163 ? 103.214 99.676  64.836  1.00 53.04  ? 153 ASP B N   1 
ATOM 2937 C CA  . ASP B 2 163 ? 102.941 101.081 64.571  1.00 46.20  ? 153 ASP B CA  1 
ATOM 2938 C C   . ASP B 2 163 ? 101.650 101.431 65.301  1.00 40.40  ? 153 ASP B C   1 
ATOM 2939 O O   . ASP B 2 163 ? 101.182 100.674 66.157  1.00 49.67  ? 153 ASP B O   1 
ATOM 2940 C CB  . ASP B 2 163 ? 102.870 101.357 63.064  1.00 48.52  ? 153 ASP B CB  1 
ATOM 2941 C CG  . ASP B 2 163 ? 101.773 100.572 62.371  1.00 57.70  ? 153 ASP B CG  1 
ATOM 2942 O OD1 . ASP B 2 163 ? 100.608 101.014 62.408  1.00 59.89  ? 153 ASP B OD1 1 
ATOM 2943 O OD2 . ASP B 2 163 ? 102.077 99.513  61.785  1.00 55.66  ? 153 ASP B OD2 1 
ATOM 2944 N N   . ASP B 2 164 ? 101.066 102.580 64.964  1.00 38.05  ? 154 ASP B N   1 
ATOM 2945 C CA  . ASP B 2 164 ? 99.844  103.005 65.637  1.00 44.66  ? 154 ASP B CA  1 
ATOM 2946 C C   . ASP B 2 164 ? 98.649  102.134 65.280  1.00 51.19  ? 154 ASP B C   1 
ATOM 2947 O O   . ASP B 2 164 ? 97.630  102.191 65.975  1.00 48.80  ? 154 ASP B O   1 
ATOM 2948 C CB  . ASP B 2 164 ? 99.532  104.464 65.309  1.00 49.83  ? 154 ASP B CB  1 
ATOM 2949 C CG  . ASP B 2 164 ? 100.441 105.433 66.035  1.00 55.75  ? 154 ASP B CG  1 
ATOM 2950 O OD1 . ASP B 2 164 ? 100.896 105.103 67.149  1.00 56.16  ? 154 ASP B OD1 1 
ATOM 2951 O OD2 . ASP B 2 164 ? 100.693 106.529 65.494  1.00 56.26  ? 154 ASP B OD2 1 
ATOM 2952 N N   . ASN B 2 165 ? 98.747  101.337 64.214  1.00 52.40  ? 155 ASN B N   1 
ATOM 2953 C CA  . ASN B 2 165 ? 97.633  100.530 63.744  1.00 41.97  ? 155 ASN B CA  1 
ATOM 2954 C C   . ASN B 2 165 ? 97.847  99.031  63.892  1.00 47.71  ? 155 ASN B C   1 
ATOM 2955 O O   . ASN B 2 165 ? 96.873  98.279  63.807  1.00 52.50  ? 155 ASN B O   1 
ATOM 2956 C CB  . ASN B 2 165 ? 97.347  100.844 62.268  1.00 46.05  ? 155 ASN B CB  1 
ATOM 2957 C CG  . ASN B 2 165 ? 96.025  100.281 61.794  1.00 56.37  ? 155 ASN B CG  1 
ATOM 2958 O OD1 . ASN B 2 165 ? 95.079  100.150 62.569  1.00 55.69  ? 155 ASN B OD1 1 
ATOM 2959 N ND2 . ASN B 2 165 ? 95.955  99.935  60.515  1.00 51.82  ? 155 ASN B ND2 1 
ATOM 2960 N N   . GLN B 2 166 ? 99.077  98.578  64.117  1.00 52.23  ? 156 GLN B N   1 
ATOM 2961 C CA  . GLN B 2 166 ? 99.380  97.158  64.221  1.00 47.13  ? 156 GLN B CA  1 
ATOM 2962 C C   . GLN B 2 166 ? 100.045 96.846  65.553  1.00 43.24  ? 156 GLN B C   1 
ATOM 2963 O O   . GLN B 2 166 ? 100.891 97.606  66.028  1.00 51.63  ? 156 GLN B O   1 
ATOM 2964 C CB  . GLN B 2 166 ? 100.286 96.701  63.081  1.00 44.42  ? 156 GLN B CB  1 
ATOM 2965 C CG  . GLN B 2 166 ? 99.590  96.593  61.744  1.00 48.96  ? 156 GLN B CG  1 
ATOM 2966 C CD  . GLN B 2 166 ? 100.482 95.991  60.685  1.00 56.46  ? 156 GLN B CD  1 
ATOM 2967 O OE1 . GLN B 2 166 ? 101.705 96.011  60.804  1.00 52.01  ? 156 GLN B OE1 1 
ATOM 2968 N NE2 . GLN B 2 166 ? 99.873  95.440  59.644  1.00 53.46  ? 156 GLN B NE2 1 
ATOM 2969 N N   . ILE B 2 167 ? 99.661  95.719  66.144  1.00 37.48  ? 157 ILE B N   1 
ATOM 2970 C CA  . ILE B 2 167 ? 100.270 95.233  67.378  1.00 38.68  ? 157 ILE B CA  1 
ATOM 2971 C C   . ILE B 2 167 ? 100.293 93.712  67.326  1.00 27.85  ? 157 ILE B C   1 
ATOM 2972 O O   . ILE B 2 167 ? 99.370  93.084  66.801  1.00 34.96  ? 157 ILE B O   1 
ATOM 2973 C CB  . ILE B 2 167 ? 99.506  95.756  68.615  1.00 36.44  ? 157 ILE B CB  1 
ATOM 2974 C CG1 . ILE B 2 167 ? 100.169 95.292  69.910  1.00 29.54  ? 157 ILE B CG1 1 
ATOM 2975 C CG2 . ILE B 2 167 ? 98.057  95.309  68.577  1.00 31.13  ? 157 ILE B CG2 1 
ATOM 2976 C CD1 . ILE B 2 167 ? 99.510  95.838  71.140  1.00 23.64  ? 157 ILE B CD1 1 
ATOM 2977 N N   . VAL B 2 168 ? 101.353 93.118  67.865  1.00 21.85  ? 158 VAL B N   1 
ATOM 2978 C CA  . VAL B 2 168 ? 101.483 91.668  67.961  1.00 34.48  ? 158 VAL B CA  1 
ATOM 2979 C C   . VAL B 2 168 ? 101.327 91.282  69.422  1.00 34.87  ? 158 VAL B C   1 
ATOM 2980 O O   . VAL B 2 168 ? 101.949 91.888  70.300  1.00 32.61  ? 158 VAL B O   1 
ATOM 2981 C CB  . VAL B 2 168 ? 102.826 91.174  67.396  1.00 32.18  ? 158 VAL B CB  1 
ATOM 2982 C CG1 . VAL B 2 168 ? 103.105 89.759  67.854  1.00 39.75  ? 158 VAL B CG1 1 
ATOM 2983 C CG2 . VAL B 2 168 ? 102.809 91.221  65.885  1.00 38.50  ? 158 VAL B CG2 1 
ATOM 2984 N N   . THR B 2 169 ? 100.497 90.275  69.680  1.00 34.04  ? 159 THR B N   1 
ATOM 2985 C CA  . THR B 2 169 ? 100.242 89.782  71.024  1.00 34.81  ? 159 THR B CA  1 
ATOM 2986 C C   . THR B 2 169 ? 100.552 88.295  71.103  1.00 28.12  ? 159 THR B C   1 
ATOM 2987 O O   . THR B 2 169 ? 100.309 87.549  70.153  1.00 31.46  ? 159 THR B O   1 
ATOM 2988 C CB  . THR B 2 169 ? 98.787  90.022  71.442  1.00 31.17  ? 159 THR B CB  1 
ATOM 2989 O OG1 . THR B 2 169 ? 97.910  89.352  70.533  1.00 40.36  ? 159 THR B OG1 1 
ATOM 2990 C CG2 . THR B 2 169 ? 98.464  91.502  71.440  1.00 35.57  ? 159 THR B CG2 1 
ATOM 2991 N N   . SER B 2 170 ? 101.096 87.874  72.238  1.00 34.33  ? 160 SER B N   1 
ATOM 2992 C CA  . SER B 2 170 ? 101.264 86.467  72.563  1.00 34.93  ? 160 SER B CA  1 
ATOM 2993 C C   . SER B 2 170 ? 100.314 86.100  73.692  1.00 41.80  ? 160 SER B C   1 
ATOM 2994 O O   . SER B 2 170 ? 100.067 86.905  74.594  1.00 48.00  ? 160 SER B O   1 
ATOM 2995 C CB  . SER B 2 170 ? 102.701 86.158  72.975  1.00 41.56  ? 160 SER B CB  1 
ATOM 2996 O OG  . SER B 2 170 ? 103.050 86.855  74.153  1.00 44.77  ? 160 SER B OG  1 
ATOM 2997 N N   . SER B 2 171 ? 99.775  84.888  73.635  1.00 35.19  ? 161 SER B N   1 
ATOM 2998 C CA  . SER B 2 171 ? 98.758  84.457  74.576  1.00 39.30  ? 161 SER B CA  1 
ATOM 2999 C C   . SER B 2 171 ? 99.138  83.113  75.178  1.00 42.30  ? 161 SER B C   1 
ATOM 3000 O O   . SER B 2 171 ? 100.039 82.420  74.702  1.00 48.04  ? 161 SER B O   1 
ATOM 3001 C CB  . SER B 2 171 ? 97.385  84.370  73.910  1.00 38.61  ? 161 SER B CB  1 
ATOM 3002 O OG  . SER B 2 171 ? 96.413  83.901  74.824  1.00 46.46  ? 161 SER B OG  1 
ATOM 3003 N N   . GLY B 2 172 ? 98.422  82.748  76.236  1.00 38.12  ? 162 GLY B N   1 
ATOM 3004 C CA  . GLY B 2 172 ? 98.539  81.446  76.853  1.00 38.51  ? 162 GLY B CA  1 
ATOM 3005 C C   . GLY B 2 172 ? 97.816  80.329  76.142  1.00 51.37  ? 162 GLY B C   1 
ATOM 3006 O O   . GLY B 2 172 ? 97.869  79.183  76.594  1.00 53.46  ? 162 GLY B O   1 
ATOM 3007 N N   . ASP B 2 173 ? 97.127  80.630  75.042  1.00 52.21  ? 163 ASP B N   1 
ATOM 3008 C CA  . ASP B 2 173 ? 96.511  79.615  74.202  1.00 42.86  ? 163 ASP B CA  1 
ATOM 3009 C C   . ASP B 2 173 ? 97.473  79.067  73.156  1.00 42.64  ? 163 ASP B C   1 
ATOM 3010 O O   . ASP B 2 173 ? 97.024  78.510  72.148  1.00 53.12  ? 163 ASP B O   1 
ATOM 3011 C CB  . ASP B 2 173 ? 95.257  80.174  73.526  1.00 40.71  ? 163 ASP B CB  1 
ATOM 3012 C CG  . ASP B 2 173 ? 95.561  81.298  72.553  1.00 46.67  ? 163 ASP B CG  1 
ATOM 3013 O OD1 . ASP B 2 173 ? 96.719  81.746  72.488  1.00 48.44  ? 163 ASP B OD1 1 
ATOM 3014 O OD2 . ASP B 2 173 ? 94.637  81.731  71.838  1.00 54.00  ? 163 ASP B OD2 1 
ATOM 3015 N N   . THR B 2 174 ? 98.779  79.237  73.369  1.00 36.62  ? 164 THR B N   1 
ATOM 3016 C CA  . THR B 2 174 ? 99.873  78.682  72.571  1.00 47.65  ? 164 THR B CA  1 
ATOM 3017 C C   . THR B 2 174 ? 100.055 79.385  71.232  1.00 50.93  ? 164 THR B C   1 
ATOM 3018 O O   . THR B 2 174 ? 100.836 78.913  70.399  1.00 53.97  ? 164 THR B O   1 
ATOM 3019 C CB  . THR B 2 174 ? 99.719  77.174  72.328  1.00 46.96  ? 164 THR B CB  1 
ATOM 3020 O OG1 . THR B 2 174 ? 98.608  76.934  71.457  1.00 41.89  ? 164 THR B OG1 1 
ATOM 3021 C CG2 . THR B 2 174 ? 99.497  76.435  73.637  1.00 44.47  ? 164 THR B CG2 1 
ATOM 3022 N N   . THR B 2 175 ? 99.370  80.502  70.997  1.00 46.92  ? 165 THR B N   1 
ATOM 3023 C CA  . THR B 2 175 ? 99.432  81.192  69.718  1.00 46.18  ? 165 THR B CA  1 
ATOM 3024 C C   . THR B 2 175 ? 99.810  82.652  69.916  1.00 46.24  ? 165 THR B C   1 
ATOM 3025 O O   . THR B 2 175 ? 99.522  83.253  70.953  1.00 53.26  ? 165 THR B O   1 
ATOM 3026 C CB  . THR B 2 175 ? 98.096  81.123  68.962  1.00 48.03  ? 165 THR B CB  1 
ATOM 3027 O OG1 . THR B 2 175 ? 97.084  81.811  69.707  1.00 47.53  ? 165 THR B OG1 1 
ATOM 3028 C CG2 . THR B 2 175 ? 97.669  79.682  68.754  1.00 45.92  ? 165 THR B CG2 1 
ATOM 3029 N N   . CYS B 2 176 ? 100.463 83.213  68.903  1.00 45.24  ? 166 CYS B N   1 
ATOM 3030 C CA  . CYS B 2 176 ? 100.665 84.647  68.779  1.00 41.90  ? 166 CYS B CA  1 
ATOM 3031 C C   . CYS B 2 176 ? 99.792  85.166  67.645  1.00 46.76  ? 166 CYS B C   1 
ATOM 3032 O O   . CYS B 2 176 ? 99.475  84.435  66.704  1.00 52.70  ? 166 CYS B O   1 
ATOM 3033 C CB  . CYS B 2 176 ? 102.132 84.987  68.504  1.00 40.79  ? 166 CYS B CB  1 
ATOM 3034 S SG  . CYS B 2 176 ? 103.290 84.466  69.782  1.00 63.40  ? 166 CYS B SG  1 
ATOM 3035 N N   . ALA B 2 177 ? 99.402  86.433  67.739  1.00 41.95  ? 167 ALA B N   1 
ATOM 3036 C CA  . ALA B 2 177 ? 98.525  87.027  66.744  1.00 37.33  ? 167 ALA B CA  1 
ATOM 3037 C C   . ALA B 2 177 ? 99.010  88.417  66.370  1.00 47.16  ? 167 ALA B C   1 
ATOM 3038 O O   . ALA B 2 177 ? 99.544  89.152  67.202  1.00 45.32  ? 167 ALA B O   1 
ATOM 3039 C CB  . ALA B 2 177 ? 97.083  87.103  67.249  1.00 40.41  ? 167 ALA B CB  1 
ATOM 3040 N N   . LEU B 2 178 ? 98.813  88.764  65.103  1.00 46.91  ? 168 LEU B N   1 
ATOM 3041 C CA  . LEU B 2 178 ? 99.007  90.119  64.608  1.00 40.44  ? 168 LEU B CA  1 
ATOM 3042 C C   . LEU B 2 178 ? 97.643  90.761  64.403  1.00 38.89  ? 168 LEU B C   1 
ATOM 3043 O O   . LEU B 2 178 ? 96.770  90.174  63.759  1.00 43.60  ? 168 LEU B O   1 
ATOM 3044 C CB  . LEU B 2 178 ? 99.796  90.110  63.300  1.00 34.63  ? 168 LEU B CB  1 
ATOM 3045 C CG  . LEU B 2 178 ? 99.846  91.412  62.505  1.00 41.67  ? 168 LEU B CG  1 
ATOM 3046 C CD1 . LEU B 2 178 ? 100.535 92.506  63.300  1.00 42.02  ? 168 LEU B CD1 1 
ATOM 3047 C CD2 . LEU B 2 178 ? 100.547 91.186  61.180  1.00 49.92  ? 168 LEU B CD2 1 
ATOM 3048 N N   . TRP B 2 179 ? 97.458  91.954  64.959  1.00 38.60  ? 169 TRP B N   1 
ATOM 3049 C CA  . TRP B 2 179 ? 96.157  92.606  64.997  1.00 35.17  ? 169 TRP B CA  1 
ATOM 3050 C C   . TRP B 2 179 ? 96.158  93.873  64.157  1.00 41.49  ? 169 TRP B C   1 
ATOM 3051 O O   . TRP B 2 179 ? 97.154  94.600  64.107  1.00 46.99  ? 169 TRP B O   1 
ATOM 3052 C CB  . TRP B 2 179 ? 95.759  92.950  66.432  1.00 38.20  ? 169 TRP B CB  1 
ATOM 3053 C CG  . TRP B 2 179 ? 95.680  91.766  67.326  1.00 45.07  ? 169 TRP B CG  1 
ATOM 3054 C CD1 . TRP B 2 179 ? 96.714  91.141  67.951  1.00 39.90  ? 169 TRP B CD1 1 
ATOM 3055 C CD2 . TRP B 2 179 ? 94.496  91.063  67.705  1.00 39.96  ? 169 TRP B CD2 1 
ATOM 3056 N NE1 . TRP B 2 179 ? 96.250  90.087  68.693  1.00 37.91  ? 169 TRP B NE1 1 
ATOM 3057 C CE2 . TRP B 2 179 ? 94.889  90.018  68.559  1.00 42.34  ? 169 TRP B CE2 1 
ATOM 3058 C CE3 . TRP B 2 179 ? 93.141  91.215  67.406  1.00 35.58  ? 169 TRP B CE3 1 
ATOM 3059 C CZ2 . TRP B 2 179 ? 93.978  89.132  69.116  1.00 44.35  ? 169 TRP B CZ2 1 
ATOM 3060 C CZ3 . TRP B 2 179 ? 92.242  90.336  67.956  1.00 40.37  ? 169 TRP B CZ3 1 
ATOM 3061 C CH2 . TRP B 2 179 ? 92.662  89.307  68.802  1.00 43.06  ? 169 TRP B CH2 1 
ATOM 3062 N N   . ASP B 2 180 ? 95.032  94.130  63.499  1.00 51.72  ? 170 ASP B N   1 
ATOM 3063 C CA  . ASP B 2 180 ? 94.740  95.426  62.899  1.00 45.39  ? 170 ASP B CA  1 
ATOM 3064 C C   . ASP B 2 180 ? 93.881  96.210  63.884  1.00 47.14  ? 170 ASP B C   1 
ATOM 3065 O O   . ASP B 2 180 ? 92.715  95.872  64.104  1.00 49.09  ? 170 ASP B O   1 
ATOM 3066 C CB  . ASP B 2 180 ? 94.028  95.257  61.560  1.00 41.35  ? 170 ASP B CB  1 
ATOM 3067 C CG  . ASP B 2 180 ? 93.799  96.574  60.856  1.00 55.31  ? 170 ASP B CG  1 
ATOM 3068 O OD1 . ASP B 2 180 ? 94.761  97.112  60.270  1.00 58.09  ? 170 ASP B OD1 1 
ATOM 3069 O OD2 . ASP B 2 180 ? 92.658  97.075  60.891  1.00 59.06  ? 170 ASP B OD2 1 
ATOM 3070 N N   . ILE B 2 181 ? 94.460  97.252  64.479  1.00 34.72  ? 171 ILE B N   1 
ATOM 3071 C CA  . ILE B 2 181 ? 93.777  97.950  65.562  1.00 45.24  ? 171 ILE B CA  1 
ATOM 3072 C C   . ILE B 2 181 ? 92.544  98.680  65.042  1.00 51.17  ? 171 ILE B C   1 
ATOM 3073 O O   . ILE B 2 181 ? 91.508  98.728  65.715  1.00 45.36  ? 171 ILE B O   1 
ATOM 3074 C CB  . ILE B 2 181 ? 94.748  98.905  66.279  1.00 40.42  ? 171 ILE B CB  1 
ATOM 3075 C CG1 . ILE B 2 181 ? 95.929  98.126  66.852  1.00 38.82  ? 171 ILE B CG1 1 
ATOM 3076 C CG2 . ILE B 2 181 ? 94.041  99.641  67.398  1.00 38.79  ? 171 ILE B CG2 1 
ATOM 3077 C CD1 . ILE B 2 181 ? 96.935  98.990  67.560  1.00 42.22  ? 171 ILE B CD1 1 
ATOM 3078 N N   . GLU B 2 182 ? 92.625  99.243  63.835  1.00 51.49  ? 172 GLU B N   1 
ATOM 3079 C CA  . GLU B 2 182 ? 91.509  100.029 63.315  1.00 54.18  ? 172 GLU B CA  1 
ATOM 3080 C C   . GLU B 2 182 ? 90.263  99.174  63.122  1.00 55.22  ? 172 GLU B C   1 
ATOM 3081 O O   . GLU B 2 182 ? 89.156  99.591  63.478  1.00 58.11  ? 172 GLU B O   1 
ATOM 3082 C CB  . GLU B 2 182 ? 91.909  100.693 61.999  1.00 55.47  ? 172 GLU B CB  1 
ATOM 3083 C CG  . GLU B 2 182 ? 90.785  101.455 61.315  1.00 56.92  ? 172 GLU B CG  1 
ATOM 3084 C CD  . GLU B 2 182 ? 90.331  102.669 62.102  1.00 65.48  ? 172 GLU B CD  1 
ATOM 3085 O OE1 . GLU B 2 182 ? 91.135  103.204 62.895  1.00 60.85  ? 172 GLU B OE1 1 
ATOM 3086 O OE2 . GLU B 2 182 ? 89.168  103.089 61.926  1.00 63.98  ? 172 GLU B OE2 1 
ATOM 3087 N N   . THR B 2 183 ? 90.420  97.975  62.567  1.00 43.71  ? 173 THR B N   1 
ATOM 3088 C CA  . THR B 2 183 ? 89.292  97.075  62.373  1.00 44.59  ? 173 THR B CA  1 
ATOM 3089 C C   . THR B 2 183 ? 89.060  96.147  63.557  1.00 49.13  ? 173 THR B C   1 
ATOM 3090 O O   . THR B 2 183 ? 87.999  95.521  63.633  1.00 45.07  ? 173 THR B O   1 
ATOM 3091 C CB  . THR B 2 183 ? 89.488  96.238  61.105  1.00 44.02  ? 173 THR B CB  1 
ATOM 3092 O OG1 . THR B 2 183 ? 90.721  95.516  61.192  1.00 51.23  ? 173 THR B OG1 1 
ATOM 3093 C CG2 . THR B 2 183 ? 89.519  97.133  59.882  1.00 42.17  ? 173 THR B CG2 1 
ATOM 3094 N N   . GLY B 2 184 ? 90.018  96.043  64.475  1.00 48.47  ? 174 GLY B N   1 
ATOM 3095 C CA  . GLY B 2 184 ? 89.852  95.195  65.636  1.00 46.98  ? 174 GLY B CA  1 
ATOM 3096 C C   . GLY B 2 184 ? 89.976  93.713  65.378  1.00 50.80  ? 174 GLY B C   1 
ATOM 3097 O O   . GLY B 2 184 ? 89.648  92.918  66.263  1.00 52.37  ? 174 GLY B O   1 
ATOM 3098 N N   . GLN B 2 185 ? 90.448  93.313  64.203  1.00 51.72  ? 175 GLN B N   1 
ATOM 3099 C CA  . GLN B 2 185 ? 90.554  91.912  63.831  1.00 52.38  ? 175 GLN B CA  1 
ATOM 3100 C C   . GLN B 2 185 ? 92.018  91.511  63.723  1.00 56.50  ? 175 GLN B C   1 
ATOM 3101 O O   . GLN B 2 185 ? 92.869  92.309  63.323  1.00 60.63  ? 175 GLN B O   1 
ATOM 3102 C CB  . GLN B 2 185 ? 89.842  91.639  62.503  1.00 50.50  ? 175 GLN B CB  1 
ATOM 3103 C CG  . GLN B 2 185 ? 88.400  92.118  62.457  1.00 57.71  ? 175 GLN B CG  1 
ATOM 3104 C CD  . GLN B 2 185 ? 87.521  91.434  63.484  1.00 62.57  ? 175 GLN B CD  1 
ATOM 3105 O OE1 . GLN B 2 185 ? 87.744  90.277  63.838  1.00 61.28  ? 175 GLN B OE1 1 
ATOM 3106 N NE2 . GLN B 2 185 ? 86.515  92.150  63.972  1.00 57.07  ? 175 GLN B NE2 1 
ATOM 3107 N N   . GLN B 2 186 ? 92.303  90.258  64.066  1.00 54.21  ? 176 GLN B N   1 
ATOM 3108 C CA  . GLN B 2 186 ? 93.658  89.733  63.948  1.00 55.27  ? 176 GLN B CA  1 
ATOM 3109 C C   . GLN B 2 186 ? 93.896  89.292  62.510  1.00 51.49  ? 176 GLN B C   1 
ATOM 3110 O O   . GLN B 2 186 ? 93.287  88.329  62.033  1.00 48.97  ? 176 GLN B O   1 
ATOM 3111 C CB  . GLN B 2 186 ? 93.884  88.588  64.931  1.00 49.58  ? 176 GLN B CB  1 
ATOM 3112 C CG  . GLN B 2 186 ? 92.733  87.613  65.046  1.00 49.36  ? 176 GLN B CG  1 
ATOM 3113 C CD  . GLN B 2 186 ? 92.978  86.552  66.097  1.00 59.33  ? 176 GLN B CD  1 
ATOM 3114 O OE1 . GLN B 2 186 ? 93.976  86.591  66.815  1.00 55.96  ? 176 GLN B OE1 1 
ATOM 3115 N NE2 . GLN B 2 186 ? 92.064  85.596  66.197  1.00 55.72  ? 176 GLN B NE2 1 
ATOM 3116 N N   . THR B 2 187 ? 94.784  90.007  61.819  1.00 43.72  ? 177 THR B N   1 
ATOM 3117 C CA  . THR B 2 187 ? 95.048  89.712  60.417  1.00 41.59  ? 177 THR B CA  1 
ATOM 3118 C C   . THR B 2 187 ? 95.812  88.406  60.261  1.00 48.48  ? 177 THR B C   1 
ATOM 3119 O O   . THR B 2 187 ? 95.550  87.634  59.331  1.00 56.60  ? 177 THR B O   1 
ATOM 3120 C CB  . THR B 2 187 ? 95.818  90.866  59.782  1.00 48.39  ? 177 THR B CB  1 
ATOM 3121 O OG1 . THR B 2 187 ? 97.058  91.048  60.471  1.00 51.12  ? 177 THR B OG1 1 
ATOM 3122 C CG2 . THR B 2 187 ? 95.013  92.146  59.874  1.00 45.77  ? 177 THR B CG2 1 
ATOM 3123 N N   . THR B 2 188 ? 96.764  88.143  61.152  1.00 46.43  ? 178 THR B N   1 
ATOM 3124 C CA  . THR B 2 188 ? 97.591  86.949  61.086  1.00 40.34  ? 178 THR B CA  1 
ATOM 3125 C C   . THR B 2 188 ? 97.594  86.259  62.440  1.00 45.87  ? 178 THR B C   1 
ATOM 3126 O O   . THR B 2 188 ? 97.639  86.918  63.482  1.00 54.98  ? 178 THR B O   1 
ATOM 3127 C CB  . THR B 2 188 ? 99.025  87.294  60.679  1.00 46.27  ? 178 THR B CB  1 
ATOM 3128 O OG1 . THR B 2 188 ? 99.003  88.140  59.524  1.00 50.35  ? 178 THR B OG1 1 
ATOM 3129 C CG2 . THR B 2 188 ? 99.810  86.033  60.356  1.00 47.20  ? 178 THR B CG2 1 
ATOM 3130 N N   . THR B 2 189 ? 97.537  84.932  62.421  1.00 50.08  ? 179 THR B N   1 
ATOM 3131 C CA  . THR B 2 189 ? 97.668  84.111  63.616  1.00 49.77  ? 179 THR B CA  1 
ATOM 3132 C C   . THR B 2 189 ? 98.902  83.235  63.462  1.00 51.52  ? 179 THR B C   1 
ATOM 3133 O O   . THR B 2 189 ? 99.067  82.566  62.437  1.00 50.34  ? 179 THR B O   1 
ATOM 3134 C CB  . THR B 2 189 ? 96.423  83.252  63.844  1.00 52.44  ? 179 THR B CB  1 
ATOM 3135 O OG1 . THR B 2 189 ? 95.271  84.098  63.935  1.00 54.56  ? 179 THR B OG1 1 
ATOM 3136 C CG2 . THR B 2 189 ? 96.555  82.458  65.129  1.00 52.35  ? 179 THR B CG2 1 
ATOM 3137 N N   . PHE B 2 190 ? 99.764  83.246  64.471  1.00 54.00  ? 180 PHE B N   1 
ATOM 3138 C CA  . PHE B 2 190 ? 101.024 82.511  64.450  1.00 46.63  ? 180 PHE B CA  1 
ATOM 3139 C C   . PHE B 2 190 ? 100.903 81.294  65.357  1.00 52.77  ? 180 PHE B C   1 
ATOM 3140 O O   . PHE B 2 190 ? 100.920 81.424  66.585  1.00 52.17  ? 180 PHE B O   1 
ATOM 3141 C CB  . PHE B 2 190 ? 102.176 83.414  64.880  1.00 44.62  ? 180 PHE B CB  1 
ATOM 3142 C CG  . PHE B 2 190 ? 102.295 84.666  64.063  1.00 48.35  ? 180 PHE B CG  1 
ATOM 3143 C CD1 . PHE B 2 190 ? 101.626 85.818  64.434  1.00 45.56  ? 180 PHE B CD1 1 
ATOM 3144 C CD2 . PHE B 2 190 ? 103.071 84.690  62.920  1.00 51.07  ? 180 PHE B CD2 1 
ATOM 3145 C CE1 . PHE B 2 190 ? 101.728 86.966  63.684  1.00 49.36  ? 180 PHE B CE1 1 
ATOM 3146 C CE2 . PHE B 2 190 ? 103.178 85.837  62.166  1.00 48.02  ? 180 PHE B CE2 1 
ATOM 3147 C CZ  . PHE B 2 190 ? 102.507 86.976  62.549  1.00 49.74  ? 180 PHE B CZ  1 
ATOM 3148 N N   . THR B 2 191 ? 100.788 80.116  64.752  1.00 53.86  ? 181 THR B N   1 
ATOM 3149 C CA  . THR B 2 191 ? 100.607 78.868  65.475  1.00 52.86  ? 181 THR B CA  1 
ATOM 3150 C C   . THR B 2 191 ? 101.827 77.974  65.300  1.00 48.43  ? 181 THR B C   1 
ATOM 3151 O O   . THR B 2 191 ? 102.542 78.060  64.298  1.00 47.22  ? 181 THR B O   1 
ATOM 3152 C CB  . THR B 2 191 ? 99.358  78.128  64.996  1.00 46.00  ? 181 THR B CB  1 
ATOM 3153 O OG1 . THR B 2 191 ? 99.495  77.818  63.605  1.00 52.67  ? 181 THR B OG1 1 
ATOM 3154 C CG2 . THR B 2 191 ? 98.123  78.987  65.196  1.00 45.52  ? 181 THR B CG2 1 
ATOM 3155 N N   . GLY B 2 192 ? 102.046 77.101  66.279  1.00 45.91  ? 182 GLY B N   1 
ATOM 3156 C CA  . GLY B 2 192 ? 103.152 76.166  66.229  1.00 44.24  ? 182 GLY B CA  1 
ATOM 3157 C C   . GLY B 2 192 ? 103.764 75.876  67.584  1.00 49.59  ? 182 GLY B C   1 
ATOM 3158 O O   . GLY B 2 192 ? 104.415 74.844  67.764  1.00 52.50  ? 182 GLY B O   1 
ATOM 3159 N N   . HIS B 2 193 ? 103.561 76.771  68.546  1.00 48.94  ? 183 HIS B N   1 
ATOM 3160 C CA  . HIS B 2 193 ? 103.981 76.497  69.912  1.00 36.80  ? 183 HIS B CA  1 
ATOM 3161 C C   . HIS B 2 193 ? 103.030 75.495  70.552  1.00 41.13  ? 183 HIS B C   1 
ATOM 3162 O O   . HIS B 2 193 ? 101.813 75.565  70.366  1.00 50.40  ? 183 HIS B O   1 
ATOM 3163 C CB  . HIS B 2 193 ? 104.013 77.783  70.737  1.00 44.66  ? 183 HIS B CB  1 
ATOM 3164 C CG  . HIS B 2 193 ? 105.262 78.592  70.564  1.00 46.02  ? 183 HIS B CG  1 
ATOM 3165 N ND1 . HIS B 2 193 ? 106.514 78.101  70.857  1.00 42.53  ? 183 HIS B ND1 1 
ATOM 3166 C CD2 . HIS B 2 193 ? 105.446 79.867  70.151  1.00 43.70  ? 183 HIS B CD2 1 
ATOM 3167 C CE1 . HIS B 2 193 ? 107.418 79.034  70.620  1.00 42.09  ? 183 HIS B CE1 1 
ATOM 3168 N NE2 . HIS B 2 193 ? 106.796 80.116  70.191  1.00 33.61  ? 183 HIS B NE2 1 
ATOM 3169 N N   . THR B 2 194 ? 103.588 74.549  71.301  1.00 44.18  ? 184 THR B N   1 
ATOM 3170 C CA  . THR B 2 194 ? 102.785 73.566  72.014  1.00 47.64  ? 184 THR B CA  1 
ATOM 3171 C C   . THR B 2 194 ? 102.538 73.946  73.467  1.00 48.90  ? 184 THR B C   1 
ATOM 3172 O O   . THR B 2 194 ? 101.860 73.203  74.181  1.00 52.39  ? 184 THR B O   1 
ATOM 3173 C CB  . THR B 2 194 ? 103.446 72.186  71.946  1.00 47.04  ? 184 THR B CB  1 
ATOM 3174 O OG1 . THR B 2 194 ? 104.755 72.249  72.520  1.00 49.05  ? 184 THR B OG1 1 
ATOM 3175 C CG2 . THR B 2 194 ? 103.559 71.723  70.505  1.00 39.18  ? 184 THR B CG2 1 
ATOM 3176 N N   . GLY B 2 195 ? 103.064 75.085  73.920  1.00 41.22  ? 185 GLY B N   1 
ATOM 3177 C CA  . GLY B 2 195 ? 102.815 75.570  75.261  1.00 35.21  ? 185 GLY B CA  1 
ATOM 3178 C C   . GLY B 2 195 ? 102.458 77.045  75.244  1.00 40.63  ? 185 GLY B C   1 
ATOM 3179 O O   . GLY B 2 195 ? 102.446 77.688  74.194  1.00 53.48  ? 185 GLY B O   1 
ATOM 3180 N N   . ASP B 2 196 ? 102.191 77.566  76.437  1.00 40.20  ? 186 ASP B N   1 
ATOM 3181 C CA  . ASP B 2 196 ? 101.823 78.970  76.576  1.00 39.68  ? 186 ASP B CA  1 
ATOM 3182 C C   . ASP B 2 196 ? 102.982 79.863  76.165  1.00 39.42  ? 186 ASP B C   1 
ATOM 3183 O O   . ASP B 2 196 ? 104.079 79.759  76.718  1.00 52.95  ? 186 ASP B O   1 
ATOM 3184 C CB  . ASP B 2 196 ? 101.419 79.269  78.016  1.00 44.11  ? 186 ASP B CB  1 
ATOM 3185 C CG  . ASP B 2 196 ? 100.402 78.293  78.550  1.00 58.80  ? 186 ASP B CG  1 
ATOM 3186 O OD1 . ASP B 2 196 ? 99.929  77.439  77.773  1.00 60.36  ? 186 ASP B OD1 1 
ATOM 3187 O OD2 . ASP B 2 196 ? 100.080 78.377  79.751  1.00 54.75  ? 186 ASP B OD2 1 
ATOM 3188 N N   . VAL B 2 197 ? 102.740 80.745  75.202  1.00 37.18  ? 187 VAL B N   1 
ATOM 3189 C CA  . VAL B 2 197 ? 103.747 81.721  74.804  1.00 39.28  ? 187 VAL B CA  1 
ATOM 3190 C C   . VAL B 2 197 ? 103.789 82.815  75.861  1.00 39.09  ? 187 VAL B C   1 
ATOM 3191 O O   . VAL B 2 197 ? 102.775 83.461  76.141  1.00 50.58  ? 187 VAL B O   1 
ATOM 3192 C CB  . VAL B 2 197 ? 103.446 82.298  73.415  1.00 35.82  ? 187 VAL B CB  1 
ATOM 3193 C CG1 . VAL B 2 197 ? 104.625 83.103  72.916  1.00 42.44  ? 187 VAL B CG1 1 
ATOM 3194 C CG2 . VAL B 2 197 ? 103.118 81.185  72.447  1.00 36.00  ? 187 VAL B CG2 1 
ATOM 3195 N N   . MET B 2 198 ? 104.963 83.024  76.451  1.00 33.64  ? 188 MET B N   1 
ATOM 3196 C CA  . MET B 2 198 ? 105.094 83.929  77.582  1.00 38.66  ? 188 MET B CA  1 
ATOM 3197 C C   . MET B 2 198 ? 105.649 85.294  77.211  1.00 41.10  ? 188 MET B C   1 
ATOM 3198 O O   . MET B 2 198 ? 105.439 86.252  77.960  1.00 42.48  ? 188 MET B O   1 
ATOM 3199 C CB  . MET B 2 198 ? 105.984 83.303  78.661  1.00 34.39  ? 188 MET B CB  1 
ATOM 3200 C CG  . MET B 2 198 ? 105.464 81.985  79.197  1.00 36.44  ? 188 MET B CG  1 
ATOM 3201 S SD  . MET B 2 198 ? 103.757 82.084  79.765  1.00 60.13  ? 188 MET B SD  1 
ATOM 3202 C CE  . MET B 2 198 ? 103.871 83.357  81.015  1.00 41.62  ? 188 MET B CE  1 
ATOM 3203 N N   . SER B 2 199 ? 106.350 85.408  76.089  1.00 48.94  ? 189 SER B N   1 
ATOM 3204 C CA  . SER B 2 199 ? 106.967 86.672  75.725  1.00 49.20  ? 189 SER B CA  1 
ATOM 3205 C C   . SER B 2 199 ? 107.192 86.701  74.224  1.00 52.70  ? 189 SER B C   1 
ATOM 3206 O O   . SER B 2 199 ? 107.188 85.666  73.554  1.00 58.15  ? 189 SER B O   1 
ATOM 3207 C CB  . SER B 2 199 ? 108.287 86.879  76.468  1.00 44.26  ? 189 SER B CB  1 
ATOM 3208 O OG  . SER B 2 199 ? 109.181 85.819  76.190  1.00 57.75  ? 189 SER B OG  1 
ATOM 3209 N N   . LEU B 2 200 ? 107.389 87.910  73.709  1.00 44.28  ? 190 LEU B N   1 
ATOM 3210 C CA  . LEU B 2 200 ? 107.798 88.109  72.330  1.00 41.28  ? 190 LEU B CA  1 
ATOM 3211 C C   . LEU B 2 200 ? 108.661 89.357  72.263  1.00 38.99  ? 190 LEU B C   1 
ATOM 3212 O O   . LEU B 2 200 ? 108.543 90.255  73.099  1.00 43.18  ? 190 LEU B O   1 
ATOM 3213 C CB  . LEU B 2 200 ? 106.583 88.226  71.399  1.00 43.68  ? 190 LEU B CB  1 
ATOM 3214 C CG  . LEU B 2 200 ? 105.649 89.427  71.580  1.00 42.19  ? 190 LEU B CG  1 
ATOM 3215 C CD1 . LEU B 2 200 ? 105.980 90.545  70.609  1.00 50.42  ? 190 LEU B CD1 1 
ATOM 3216 C CD2 . LEU B 2 200 ? 104.209 89.008  71.423  1.00 31.83  ? 190 LEU B CD2 1 
ATOM 3217 N N   . SER B 2 201 ? 109.529 89.407  71.260  1.00 45.27  ? 191 SER B N   1 
ATOM 3218 C CA  . SER B 2 201 ? 110.363 90.572  71.015  1.00 42.73  ? 191 SER B CA  1 
ATOM 3219 C C   . SER B 2 201 ? 110.343 90.886  69.530  1.00 50.34  ? 191 SER B C   1 
ATOM 3220 O O   . SER B 2 201 ? 110.457 89.984  68.698  1.00 48.91  ? 191 SER B O   1 
ATOM 3221 C CB  . SER B 2 201 ? 111.798 90.337  71.490  1.00 50.86  ? 191 SER B CB  1 
ATOM 3222 O OG  . SER B 2 201 ? 112.591 91.495  71.310  1.00 55.86  ? 191 SER B OG  1 
ATOM 3223 N N   . LEU B 2 202 ? 110.211 92.165  69.203  1.00 56.28  ? 192 LEU B N   1 
ATOM 3224 C CA  . LEU B 2 202 ? 110.198 92.611  67.820  1.00 46.78  ? 192 LEU B CA  1 
ATOM 3225 C C   . LEU B 2 202 ? 111.605 92.929  67.342  1.00 51.16  ? 192 LEU B C   1 
ATOM 3226 O O   . LEU B 2 202 ? 112.413 93.497  68.080  1.00 59.85  ? 192 LEU B O   1 
ATOM 3227 C CB  . LEU B 2 202 ? 109.307 93.841  67.656  1.00 44.00  ? 192 LEU B CB  1 
ATOM 3228 C CG  . LEU B 2 202 ? 107.817 93.574  67.488  1.00 48.35  ? 192 LEU B CG  1 
ATOM 3229 C CD1 . LEU B 2 202 ? 107.067 94.880  67.424  1.00 54.22  ? 192 LEU B CD1 1 
ATOM 3230 C CD2 . LEU B 2 202 ? 107.582 92.774  66.226  1.00 50.59  ? 192 LEU B CD2 1 
ATOM 3231 N N   . ALA B 2 203 ? 111.887 92.563  66.097  1.00 45.21  ? 193 ALA B N   1 
ATOM 3232 C CA  . ALA B 2 203 ? 113.140 92.945  65.480  1.00 50.40  ? 193 ALA B CA  1 
ATOM 3233 C C   . ALA B 2 203 ? 113.159 94.453  65.246  1.00 56.10  ? 193 ALA B C   1 
ATOM 3234 O O   . ALA B 2 203 ? 112.103 95.082  65.139  1.00 55.12  ? 193 ALA B O   1 
ATOM 3235 C CB  . ALA B 2 203 ? 113.334 92.206  64.160  1.00 46.61  ? 193 ALA B CB  1 
ATOM 3236 N N   . PRO B 2 204 ? 114.346 95.062  65.196  1.00 65.91  ? 194 PRO B N   1 
ATOM 3237 C CA  . PRO B 2 204 ? 114.406 96.523  65.030  1.00 58.43  ? 194 PRO B CA  1 
ATOM 3238 C C   . PRO B 2 204 ? 113.686 97.025  63.790  1.00 63.69  ? 194 PRO B C   1 
ATOM 3239 O O   . PRO B 2 204 ? 113.131 98.131  63.817  1.00 65.26  ? 194 PRO B O   1 
ATOM 3240 C CB  . PRO B 2 204 ? 115.913 96.800  64.965  1.00 56.03  ? 194 PRO B CB  1 
ATOM 3241 C CG  . PRO B 2 204 ? 116.522 95.685  65.740  1.00 55.66  ? 194 PRO B CG  1 
ATOM 3242 C CD  . PRO B 2 204 ? 115.676 94.483  65.451  1.00 59.10  ? 194 PRO B CD  1 
ATOM 3243 N N   . ASP B 2 205 ? 113.672 96.254  62.707  1.00 61.31  ? 195 ASP B N   1 
ATOM 3244 C CA  . ASP B 2 205 ? 112.936 96.622  61.506  1.00 57.26  ? 195 ASP B CA  1 
ATOM 3245 C C   . ASP B 2 205 ? 111.478 96.182  61.552  1.00 55.97  ? 195 ASP B C   1 
ATOM 3246 O O   . ASP B 2 205 ? 110.731 96.469  60.611  1.00 53.45  ? 195 ASP B O   1 
ATOM 3247 C CB  . ASP B 2 205 ? 113.612 96.030  60.266  1.00 59.99  ? 195 ASP B CB  1 
ATOM 3248 C CG  . ASP B 2 205 ? 113.646 94.518  60.288  1.00 64.62  ? 195 ASP B CG  1 
ATOM 3249 O OD1 . ASP B 2 205 ? 113.675 93.938  61.392  1.00 62.48  ? 195 ASP B OD1 1 
ATOM 3250 O OD2 . ASP B 2 205 ? 113.647 93.907  59.199  1.00 62.17  ? 195 ASP B OD2 1 
ATOM 3251 N N   . THR B 2 206 ? 111.066 95.494  62.618  1.00 55.84  ? 196 THR B N   1 
ATOM 3252 C CA  . THR B 2 206 ? 109.684 95.057  62.826  1.00 57.10  ? 196 THR B CA  1 
ATOM 3253 C C   . THR B 2 206 ? 109.171 94.188  61.681  1.00 57.04  ? 196 THR B C   1 
ATOM 3254 O O   . THR B 2 206 ? 107.971 94.160  61.401  1.00 58.81  ? 196 THR B O   1 
ATOM 3255 C CB  . THR B 2 206 ? 108.745 96.247  63.051  1.00 61.71  ? 196 THR B CB  1 
ATOM 3256 O OG1 . THR B 2 206 ? 108.643 97.019  61.848  1.00 63.15  ? 196 THR B OG1 1 
ATOM 3257 C CG2 . THR B 2 206 ? 109.265 97.129  64.174  1.00 53.00  ? 196 THR B CG2 1 
ATOM 3258 N N   . ARG B 2 207 ? 110.071 93.472  61.008  1.00 59.84  ? 197 ARG B N   1 
ATOM 3259 C CA  . ARG B 2 207 ? 109.669 92.488  60.013  1.00 58.42  ? 197 ARG B CA  1 
ATOM 3260 C C   . ARG B 2 207 ? 109.657 91.069  60.556  1.00 62.32  ? 197 ARG B C   1 
ATOM 3261 O O   . ARG B 2 207 ? 109.029 90.196  59.949  1.00 63.26  ? 197 ARG B O   1 
ATOM 3262 C CB  . ARG B 2 207 ? 110.590 92.554  58.790  1.00 60.13  ? 197 ARG B CB  1 
ATOM 3263 C CG  . ARG B 2 207 ? 110.471 93.845  58.005  1.00 63.65  ? 197 ARG B CG  1 
ATOM 3264 C CD  . ARG B 2 207 ? 111.282 93.795  56.728  1.00 62.84  ? 197 ARG B CD  1 
ATOM 3265 N NE  . ARG B 2 207 ? 111.116 95.008  55.937  1.00 69.68  ? 197 ARG B NE  1 
ATOM 3266 C CZ  . ARG B 2 207 ? 110.144 95.198  55.055  1.00 70.51  ? 197 ARG B CZ  1 
ATOM 3267 N NH1 . ARG B 2 207 ? 109.230 94.271  54.824  1.00 67.39  ? 197 ARG B NH1 1 
ATOM 3268 N NH2 . ARG B 2 207 ? 110.089 96.348  54.389  1.00 64.33  ? 197 ARG B NH2 1 
ATOM 3269 N N   . LEU B 2 208 ? 110.328 90.823  61.677  1.00 58.94  ? 198 LEU B N   1 
ATOM 3270 C CA  . LEU B 2 208 ? 110.366 89.520  62.317  1.00 48.87  ? 198 LEU B CA  1 
ATOM 3271 C C   . LEU B 2 208 ? 110.147 89.698  63.811  1.00 52.44  ? 198 LEU B C   1 
ATOM 3272 O O   . LEU B 2 208 ? 110.331 90.786  64.359  1.00 56.29  ? 198 LEU B O   1 
ATOM 3273 C CB  . LEU B 2 208 ? 111.702 88.807  62.078  1.00 46.66  ? 198 LEU B CB  1 
ATOM 3274 C CG  . LEU B 2 208 ? 112.184 88.612  60.643  1.00 51.72  ? 198 LEU B CG  1 
ATOM 3275 C CD1 . LEU B 2 208 ? 113.586 88.038  60.646  1.00 53.33  ? 198 LEU B CD1 1 
ATOM 3276 C CD2 . LEU B 2 208 ? 111.246 87.705  59.880  1.00 50.51  ? 198 LEU B CD2 1 
ATOM 3277 N N   . PHE B 2 209 ? 109.743 88.616  64.470  1.00 42.63  ? 199 PHE B N   1 
ATOM 3278 C CA  . PHE B 2 209 ? 109.718 88.602  65.923  1.00 42.18  ? 199 PHE B CA  1 
ATOM 3279 C C   . PHE B 2 209 ? 109.933 87.181  66.419  1.00 43.88  ? 199 PHE B C   1 
ATOM 3280 O O   . PHE B 2 209 ? 109.529 86.213  65.773  1.00 44.09  ? 199 PHE B O   1 
ATOM 3281 C CB  . PHE B 2 209 ? 108.411 89.183  66.484  1.00 42.58  ? 199 PHE B CB  1 
ATOM 3282 C CG  . PHE B 2 209 ? 107.195 88.346  66.219  1.00 47.79  ? 199 PHE B CG  1 
ATOM 3283 C CD1 . PHE B 2 209 ? 106.500 88.467  65.029  1.00 54.06  ? 199 PHE B CD1 1 
ATOM 3284 C CD2 . PHE B 2 209 ? 106.730 87.456  67.170  1.00 41.08  ? 199 PHE B CD2 1 
ATOM 3285 C CE1 . PHE B 2 209 ? 105.376 87.708  64.788  1.00 49.47  ? 199 PHE B CE1 1 
ATOM 3286 C CE2 . PHE B 2 209 ? 105.610 86.693  66.932  1.00 46.64  ? 199 PHE B CE2 1 
ATOM 3287 C CZ  . PHE B 2 209 ? 104.931 86.820  65.741  1.00 47.51  ? 199 PHE B CZ  1 
ATOM 3288 N N   . VAL B 2 210 ? 110.592 87.071  67.569  1.00 44.54  ? 200 VAL B N   1 
ATOM 3289 C CA  . VAL B 2 210 ? 110.827 85.796  68.230  1.00 37.48  ? 200 VAL B CA  1 
ATOM 3290 C C   . VAL B 2 210 ? 109.888 85.703  69.422  1.00 37.88  ? 200 VAL B C   1 
ATOM 3291 O O   . VAL B 2 210 ? 109.557 86.710  70.055  1.00 43.19  ? 200 VAL B O   1 
ATOM 3292 C CB  . VAL B 2 210 ? 112.295 85.626  68.672  1.00 40.18  ? 200 VAL B CB  1 
ATOM 3293 C CG1 . VAL B 2 210 ? 113.193 85.402  67.471  1.00 44.55  ? 200 VAL B CG1 1 
ATOM 3294 C CG2 . VAL B 2 210 ? 112.757 86.842  69.456  1.00 46.81  ? 200 VAL B CG2 1 
ATOM 3295 N N   . SER B 2 211 ? 109.449 84.486  69.722  1.00 48.91  ? 201 SER B N   1 
ATOM 3296 C CA  . SER B 2 211 ? 108.591 84.230  70.868  1.00 43.61  ? 201 SER B CA  1 
ATOM 3297 C C   . SER B 2 211 ? 109.092 83.012  71.626  1.00 50.36  ? 201 SER B C   1 
ATOM 3298 O O   . SER B 2 211 ? 109.547 82.038  71.023  1.00 55.18  ? 201 SER B O   1 
ATOM 3299 C CB  . SER B 2 211 ? 107.140 84.010  70.439  1.00 40.24  ? 201 SER B CB  1 
ATOM 3300 O OG  . SER B 2 211 ? 107.027 82.892  69.581  1.00 48.57  ? 201 SER B OG  1 
ATOM 3301 N N   . GLY B 2 212 ? 109.004 83.074  72.951  1.00 47.88  ? 202 GLY B N   1 
ATOM 3302 C CA  . GLY B 2 212 ? 109.347 81.960  73.816  1.00 45.79  ? 202 GLY B CA  1 
ATOM 3303 C C   . GLY B 2 212 ? 108.108 81.447  74.531  1.00 45.27  ? 202 GLY B C   1 
ATOM 3304 O O   . GLY B 2 212 ? 107.310 82.231  75.044  1.00 52.29  ? 202 GLY B O   1 
ATOM 3305 N N   . ALA B 2 213 ? 107.960 80.129  74.549  1.00 41.48  ? 203 ALA B N   1 
ATOM 3306 C CA  . ALA B 2 213 ? 106.783 79.490  75.116  1.00 42.98  ? 203 ALA B CA  1 
ATOM 3307 C C   . ALA B 2 213 ? 107.188 78.578  76.270  1.00 44.18  ? 203 ALA B C   1 
ATOM 3308 O O   . ALA B 2 213 ? 108.361 78.473  76.633  1.00 45.92  ? 203 ALA B O   1 
ATOM 3309 C CB  . ALA B 2 213 ? 106.012 78.714  74.046  1.00 37.63  ? 203 ALA B CB  1 
ATOM 3310 N N   . CYS B 2 214 ? 106.196 77.901  76.837  1.00 41.57  ? 204 CYS B N   1 
ATOM 3311 C CA  . CYS B 2 214 ? 106.411 76.973  77.936  1.00 42.49  ? 204 CYS B CA  1 
ATOM 3312 C C   . CYS B 2 214 ? 106.809 75.581  77.471  1.00 50.56  ? 204 CYS B C   1 
ATOM 3313 O O   . CYS B 2 214 ? 107.035 74.706  78.312  1.00 55.16  ? 204 CYS B O   1 
ATOM 3314 C CB  . CYS B 2 214 ? 105.153 76.884  78.803  1.00 45.03  ? 204 CYS B CB  1 
ATOM 3315 S SG  . CYS B 2 214 ? 104.707 78.430  79.611  1.00 64.62  ? 204 CYS B SG  1 
ATOM 3316 N N   . ASP B 2 215 ? 106.893 75.351  76.164  1.00 46.21  ? 205 ASP B N   1 
ATOM 3317 C CA  . ASP B 2 215 ? 107.491 74.137  75.630  1.00 47.35  ? 205 ASP B CA  1 
ATOM 3318 C C   . ASP B 2 215 ? 109.010 74.225  75.530  1.00 51.73  ? 205 ASP B C   1 
ATOM 3319 O O   . ASP B 2 215 ? 109.618 73.411  74.824  1.00 46.60  ? 205 ASP B O   1 
ATOM 3320 C CB  . ASP B 2 215 ? 106.890 73.809  74.263  1.00 43.08  ? 205 ASP B CB  1 
ATOM 3321 C CG  . ASP B 2 215 ? 107.002 74.956  73.283  1.00 50.19  ? 205 ASP B CG  1 
ATOM 3322 O OD1 . ASP B 2 215 ? 107.605 75.987  73.635  1.00 60.81  ? 205 ASP B OD1 1 
ATOM 3323 O OD2 . ASP B 2 215 ? 106.488 74.828  72.154  1.00 49.86  ? 205 ASP B OD2 1 
ATOM 3324 N N   . ALA B 2 216 ? 109.620 75.197  76.213  1.00 45.44  ? 206 ALA B N   1 
ATOM 3325 C CA  . ALA B 2 216 ? 111.072 75.359  76.271  1.00 39.23  ? 206 ALA B CA  1 
ATOM 3326 C C   . ALA B 2 216 ? 111.683 75.613  74.895  1.00 47.34  ? 206 ALA B C   1 
ATOM 3327 O O   . ALA B 2 216 ? 112.840 75.269  74.646  1.00 55.79  ? 206 ALA B O   1 
ATOM 3328 C CB  . ALA B 2 216 ? 111.739 74.151  76.935  1.00 46.03  ? 206 ALA B CB  1 
ATOM 3329 N N   . SER B 2 217 ? 110.920 76.218  73.990  1.00 48.00  ? 207 SER B N   1 
ATOM 3330 C CA  . SER B 2 217 ? 111.384 76.473  72.635  1.00 43.85  ? 207 SER B CA  1 
ATOM 3331 C C   . SER B 2 217 ? 111.110 77.919  72.255  1.00 51.72  ? 207 SER B C   1 
ATOM 3332 O O   . SER B 2 217 ? 110.151 78.534  72.730  1.00 53.80  ? 207 SER B O   1 
ATOM 3333 C CB  . SER B 2 217 ? 110.706 75.546  71.623  1.00 49.08  ? 207 SER B CB  1 
ATOM 3334 O OG  . SER B 2 217 ? 109.325 75.843  71.513  1.00 47.07  ? 207 SER B OG  1 
ATOM 3335 N N   . ALA B 2 218 ? 111.969 78.457  71.394  1.00 51.08  ? 208 ALA B N   1 
ATOM 3336 C CA  . ALA B 2 218 ? 111.827 79.805  70.863  1.00 41.78  ? 208 ALA B CA  1 
ATOM 3337 C C   . ALA B 2 218 ? 111.667 79.719  69.353  1.00 46.55  ? 208 ALA B C   1 
ATOM 3338 O O   . ALA B 2 218 ? 112.468 79.066  68.679  1.00 53.55  ? 208 ALA B O   1 
ATOM 3339 C CB  . ALA B 2 218 ? 113.032 80.673  71.225  1.00 40.91  ? 208 ALA B CB  1 
ATOM 3340 N N   . LYS B 2 219 ? 110.627 80.358  68.829  1.00 48.64  ? 209 LYS B N   1 
ATOM 3341 C CA  . LYS B 2 219 ? 110.338 80.346  67.404  1.00 49.41  ? 209 LYS B CA  1 
ATOM 3342 C C   . LYS B 2 219 ? 110.488 81.740  66.810  1.00 53.11  ? 209 LYS B C   1 
ATOM 3343 O O   . LYS B 2 219 ? 110.065 82.731  67.411  1.00 50.96  ? 209 LYS B O   1 
ATOM 3344 C CB  . LYS B 2 219 ? 108.931 79.808  67.141  1.00 44.74  ? 209 LYS B CB  1 
ATOM 3345 C CG  . LYS B 2 219 ? 108.798 78.324  67.418  1.00 45.53  ? 209 LYS B CG  1 
ATOM 3346 C CD  . LYS B 2 219 ? 107.385 77.836  67.196  1.00 45.28  ? 209 LYS B CD  1 
ATOM 3347 C CE  . LYS B 2 219 ? 107.295 76.340  67.386  1.00 47.38  ? 209 LYS B CE  1 
ATOM 3348 N NZ  . LYS B 2 219 ? 108.186 75.626  66.434  1.00 53.61  ? 209 LYS B NZ  1 
ATOM 3349 N N   . LEU B 2 220 ? 111.084 81.806  65.623  1.00 56.19  ? 210 LEU B N   1 
ATOM 3350 C CA  . LEU B 2 220 ? 111.236 83.049  64.879  1.00 50.67  ? 210 LEU B CA  1 
ATOM 3351 C C   . LEU B 2 220 ? 110.135 83.119  63.830  1.00 57.85  ? 210 LEU B C   1 
ATOM 3352 O O   . LEU B 2 220 ? 110.008 82.215  62.999  1.00 58.71  ? 210 LEU B O   1 
ATOM 3353 C CB  . LEU B 2 220 ? 112.612 83.122  64.221  1.00 49.71  ? 210 LEU B CB  1 
ATOM 3354 C CG  . LEU B 2 220 ? 112.859 84.244  63.214  1.00 55.50  ? 210 LEU B CG  1 
ATOM 3355 C CD1 . LEU B 2 220 ? 112.750 85.601  63.883  1.00 57.40  ? 210 LEU B CD1 1 
ATOM 3356 C CD2 . LEU B 2 220 ? 114.216 84.077  62.560  1.00 57.79  ? 210 LEU B CD2 1 
ATOM 3357 N N   . TRP B 2 221 ? 109.342 84.185  63.871  1.00 55.14  ? 211 TRP B N   1 
ATOM 3358 C CA  . TRP B 2 221 ? 108.176 84.324  63.013  1.00 44.70  ? 211 TRP B CA  1 
ATOM 3359 C C   . TRP B 2 221 ? 108.374 85.461  62.023  1.00 55.65  ? 211 TRP B C   1 
ATOM 3360 O O   . TRP B 2 221 ? 108.943 86.502  62.361  1.00 64.00  ? 211 TRP B O   1 
ATOM 3361 C CB  . TRP B 2 221 ? 106.916 84.581  63.836  1.00 45.98  ? 211 TRP B CB  1 
ATOM 3362 C CG  . TRP B 2 221 ? 106.705 83.592  64.923  1.00 50.61  ? 211 TRP B CG  1 
ATOM 3363 C CD1 . TRP B 2 221 ? 107.160 83.674  66.202  1.00 52.53  ? 211 TRP B CD1 1 
ATOM 3364 C CD2 . TRP B 2 221 ? 105.982 82.362  64.831  1.00 51.99  ? 211 TRP B CD2 1 
ATOM 3365 N NE1 . TRP B 2 221 ? 106.767 82.572  66.915  1.00 54.08  ? 211 TRP B NE1 1 
ATOM 3366 C CE2 . TRP B 2 221 ? 106.041 81.751  66.094  1.00 54.83  ? 211 TRP B CE2 1 
ATOM 3367 C CE3 . TRP B 2 221 ? 105.291 81.719  63.802  1.00 48.36  ? 211 TRP B CE3 1 
ATOM 3368 C CZ2 . TRP B 2 221 ? 105.436 80.530  66.357  1.00 53.31  ? 211 TRP B CZ2 1 
ATOM 3369 C CZ3 . TRP B 2 221 ? 104.693 80.510  64.065  1.00 46.00  ? 211 TRP B CZ3 1 
ATOM 3370 C CH2 . TRP B 2 221 ? 104.770 79.926  65.331  1.00 52.15  ? 211 TRP B CH2 1 
ATOM 3371 N N   . ASP B 2 222 ? 107.889 85.257  60.802  1.00 65.23  ? 212 ASP B N   1 
ATOM 3372 C CA  . ASP B 2 222 ? 107.821 86.314  59.804  1.00 64.37  ? 212 ASP B CA  1 
ATOM 3373 C C   . ASP B 2 222 ? 106.468 87.004  59.925  1.00 68.75  ? 212 ASP B C   1 
ATOM 3374 O O   . ASP B 2 222 ? 105.423 86.351  59.833  1.00 70.45  ? 212 ASP B O   1 
ATOM 3375 C CB  . ASP B 2 222 ? 108.022 85.743  58.402  1.00 63.85  ? 212 ASP B CB  1 
ATOM 3376 C CG  . ASP B 2 222 ? 108.379 86.806  57.382  1.00 67.71  ? 212 ASP B CG  1 
ATOM 3377 O OD1 . ASP B 2 222 ? 107.921 87.958  57.524  1.00 69.91  ? 212 ASP B OD1 1 
ATOM 3378 O OD2 . ASP B 2 222 ? 109.125 86.488  56.434  1.00 70.16  ? 212 ASP B OD2 1 
ATOM 3379 N N   . VAL B 2 223 ? 106.488 88.318  60.142  1.00 61.20  ? 213 VAL B N   1 
ATOM 3380 C CA  . VAL B 2 223 ? 105.247 89.051  60.371  1.00 59.71  ? 213 VAL B CA  1 
ATOM 3381 C C   . VAL B 2 223 ? 104.393 89.060  59.110  1.00 63.30  ? 213 VAL B C   1 
ATOM 3382 O O   . VAL B 2 223 ? 103.189 88.785  59.153  1.00 62.98  ? 213 VAL B O   1 
ATOM 3383 C CB  . VAL B 2 223 ? 105.549 90.478  60.859  1.00 63.07  ? 213 VAL B CB  1 
ATOM 3384 C CG1 . VAL B 2 223 ? 104.259 91.220  61.153  1.00 60.25  ? 213 VAL B CG1 1 
ATOM 3385 C CG2 . VAL B 2 223 ? 106.434 90.439  62.088  1.00 61.26  ? 213 VAL B CG2 1 
ATOM 3386 N N   . ARG B 2 224 ? 105.002 89.388  57.970  1.00 72.43  ? 214 ARG B N   1 
ATOM 3387 C CA  . ARG B 2 224 ? 104.239 89.516  56.733  1.00 71.30  ? 214 ARG B CA  1 
ATOM 3388 C C   . ARG B 2 224 ? 103.789 88.156  56.214  1.00 69.98  ? 214 ARG B C   1 
ATOM 3389 O O   . ARG B 2 224 ? 102.622 87.976  55.848  1.00 72.73  ? 214 ARG B O   1 
ATOM 3390 C CB  . ARG B 2 224 ? 105.073 90.244  55.680  1.00 70.21  ? 214 ARG B CB  1 
ATOM 3391 C CG  . ARG B 2 224 ? 105.431 91.670  56.053  1.00 70.67  ? 214 ARG B CG  1 
ATOM 3392 C CD  . ARG B 2 224 ? 104.182 92.499  56.298  1.00 74.39  ? 214 ARG B CD  1 
ATOM 3393 N NE  . ARG B 2 224 ? 104.496 93.877  56.655  1.00 79.89  ? 214 ARG B NE  1 
ATOM 3394 C CZ  . ARG B 2 224 ? 103.590 94.799  56.949  1.00 77.67  ? 214 ARG B CZ  1 
ATOM 3395 N NH1 . ARG B 2 224 ? 102.296 94.524  56.942  1.00 74.08  ? 214 ARG B NH1 1 
ATOM 3396 N NH2 . ARG B 2 224 ? 103.993 96.028  57.258  1.00 71.55  ? 214 ARG B NH2 1 
ATOM 3397 N N   . GLU B 2 225 ? 104.699 87.181  56.180  1.00 72.09  ? 215 GLU B N   1 
ATOM 3398 C CA  . GLU B 2 225 ? 104.354 85.878  55.621  1.00 74.61  ? 215 GLU B CA  1 
ATOM 3399 C C   . GLU B 2 225 ? 103.476 85.076  56.574  1.00 73.95  ? 215 GLU B C   1 
ATOM 3400 O O   . GLU B 2 225 ? 102.561 84.369  56.136  1.00 73.30  ? 215 GLU B O   1 
ATOM 3401 C CB  . GLU B 2 225 ? 105.626 85.104  55.279  1.00 74.66  ? 215 GLU B CB  1 
ATOM 3402 C CG  . GLU B 2 225 ? 105.401 83.914  54.363  1.00 78.55  ? 215 GLU B CG  1 
ATOM 3403 C CD  . GLU B 2 225 ? 105.054 84.326  52.944  1.00 81.15  ? 215 GLU B CD  1 
ATOM 3404 O OE1 . GLU B 2 225 ? 105.343 85.481  52.569  1.00 79.44  ? 215 GLU B OE1 1 
ATOM 3405 O OE2 . GLU B 2 225 ? 104.491 83.492  52.204  1.00 75.70  ? 215 GLU B OE2 1 
ATOM 3406 N N   . GLY B 2 226 ? 103.738 85.167  57.873  1.00 71.61  ? 216 GLY B N   1 
ATOM 3407 C CA  . GLY B 2 226 ? 102.892 84.533  58.863  1.00 71.12  ? 216 GLY B CA  1 
ATOM 3408 C C   . GLY B 2 226 ? 103.236 83.104  59.209  1.00 67.35  ? 216 GLY B C   1 
ATOM 3409 O O   . GLY B 2 226 ? 102.395 82.407  59.788  1.00 66.93  ? 216 GLY B O   1 
ATOM 3410 N N   . MET B 2 227 ? 104.441 82.643  58.890  1.00 73.73  ? 217 MET B N   1 
ATOM 3411 C CA  . MET B 2 227 ? 104.855 81.285  59.203  1.00 76.57  ? 217 MET B CA  1 
ATOM 3412 C C   . MET B 2 227 ? 106.101 81.297  60.079  1.00 72.34  ? 217 MET B C   1 
ATOM 3413 O O   . MET B 2 227 ? 106.797 82.309  60.196  1.00 71.42  ? 217 MET B O   1 
ATOM 3414 C CB  . MET B 2 227 ? 105.108 80.477  57.921  1.00 76.66  ? 217 MET B CB  1 
ATOM 3415 C CG  . MET B 2 227 ? 105.799 81.254  56.808  1.00 78.99  ? 217 MET B CG  1 
ATOM 3416 S SD  . MET B 2 227 ? 107.579 81.429  57.026  1.00 101.19 ? 217 MET B SD  1 
ATOM 3417 C CE  . MET B 2 227 ? 108.112 79.730  56.826  1.00 76.08  ? 217 MET B CE  1 
ATOM 3418 N N   . CYS B 2 228 ? 106.380 80.148  60.687  1.00 62.62  ? 218 CYS B N   1 
ATOM 3419 C CA  . CYS B 2 228 ? 107.557 79.997  61.530  1.00 67.25  ? 218 CYS B CA  1 
ATOM 3420 C C   . CYS B 2 228 ? 108.772 79.728  60.653  1.00 71.34  ? 218 CYS B C   1 
ATOM 3421 O O   . CYS B 2 228 ? 108.788 78.764  59.881  1.00 76.08  ? 218 CYS B O   1 
ATOM 3422 C CB  . CYS B 2 228 ? 107.353 78.864  62.533  1.00 68.63  ? 218 CYS B CB  1 
ATOM 3423 S SG  . CYS B 2 228 ? 108.735 78.594  63.658  1.00 70.87  ? 218 CYS B SG  1 
ATOM 3424 N N   . ARG B 2 229 ? 109.790 80.578  60.773  1.00 71.41  ? 219 ARG B N   1 
ATOM 3425 C CA  . ARG B 2 229 ? 111.004 80.391  59.990  1.00 69.30  ? 219 ARG B CA  1 
ATOM 3426 C C   . ARG B 2 229 ? 111.961 79.423  60.672  1.00 71.00  ? 219 ARG B C   1 
ATOM 3427 O O   . ARG B 2 229 ? 112.470 78.494  60.037  1.00 73.37  ? 219 ARG B O   1 
ATOM 3428 C CB  . ARG B 2 229 ? 111.680 81.738  59.741  1.00 70.50  ? 219 ARG B CB  1 
ATOM 3429 C CG  . ARG B 2 229 ? 110.843 82.690  58.912  1.00 70.97  ? 219 ARG B CG  1 
ATOM 3430 C CD  . ARG B 2 229 ? 111.537 84.025  58.741  1.00 77.54  ? 219 ARG B CD  1 
ATOM 3431 N NE  . ARG B 2 229 ? 112.816 83.894  58.055  1.00 80.44  ? 219 ARG B NE  1 
ATOM 3432 C CZ  . ARG B 2 229 ? 112.974 83.998  56.743  1.00 79.41  ? 219 ARG B CZ  1 
ATOM 3433 N NH1 . ARG B 2 229 ? 111.949 84.233  55.940  1.00 74.83  ? 219 ARG B NH1 1 
ATOM 3434 N NH2 . ARG B 2 229 ? 114.192 83.864  56.223  1.00 76.85  ? 219 ARG B NH2 1 
ATOM 3435 N N   . GLN B 2 230 ? 112.216 79.621  61.962  1.00 65.79  ? 220 GLN B N   1 
ATOM 3436 C CA  . GLN B 2 230 ? 113.173 78.801  62.687  1.00 59.91  ? 220 GLN B CA  1 
ATOM 3437 C C   . GLN B 2 230 ? 112.637 78.516  64.080  1.00 56.99  ? 220 GLN B C   1 
ATOM 3438 O O   . GLN B 2 230 ? 111.862 79.297  64.636  1.00 65.62  ? 220 GLN B O   1 
ATOM 3439 C CB  . GLN B 2 230 ? 114.544 79.488  62.783  1.00 57.83  ? 220 GLN B CB  1 
ATOM 3440 C CG  . GLN B 2 230 ? 115.134 79.883  61.437  1.00 64.41  ? 220 GLN B CG  1 
ATOM 3441 C CD  . GLN B 2 230 ? 116.448 80.621  61.557  1.00 66.98  ? 220 GLN B CD  1 
ATOM 3442 O OE1 . GLN B 2 230 ? 116.784 81.450  60.714  1.00 68.42  ? 220 GLN B OE1 1 
ATOM 3443 N NE2 . GLN B 2 230 ? 117.205 80.315  62.599  1.00 66.06  ? 220 GLN B NE2 1 
ATOM 3444 N N   . THR B 2 231 ? 113.053 77.382  64.634  1.00 55.45  ? 221 THR B N   1 
ATOM 3445 C CA  . THR B 2 231 ? 112.708 76.987  65.992  1.00 53.65  ? 221 THR B CA  1 
ATOM 3446 C C   . THR B 2 231 ? 113.993 76.762  66.770  1.00 61.11  ? 221 THR B C   1 
ATOM 3447 O O   . THR B 2 231 ? 114.894 76.060  66.298  1.00 65.99  ? 221 THR B O   1 
ATOM 3448 C CB  . THR B 2 231 ? 111.851 75.722  66.004  1.00 57.71  ? 221 THR B CB  1 
ATOM 3449 O OG1 . THR B 2 231 ? 110.677 75.933  65.210  1.00 69.59  ? 221 THR B OG1 1 
ATOM 3450 C CG2 . THR B 2 231 ? 111.435 75.379  67.423  1.00 54.98  ? 221 THR B CG2 1 
ATOM 3451 N N   . PHE B 2 232 ? 114.075 77.349  67.959  1.00 54.76  ? 222 PHE B N   1 
ATOM 3452 C CA  . PHE B 2 232 ? 115.270 77.279  68.789  1.00 45.08  ? 222 PHE B CA  1 
ATOM 3453 C C   . PHE B 2 232 ? 114.936 76.553  70.081  1.00 45.82  ? 222 PHE B C   1 
ATOM 3454 O O   . PHE B 2 232 ? 114.042 76.976  70.820  1.00 56.57  ? 222 PHE B O   1 
ATOM 3455 C CB  . PHE B 2 232 ? 115.810 78.677  69.083  1.00 47.42  ? 222 PHE B CB  1 
ATOM 3456 C CG  . PHE B 2 232 ? 116.058 79.499  67.857  1.00 45.99  ? 222 PHE B CG  1 
ATOM 3457 C CD1 . PHE B 2 232 ? 115.052 80.280  67.318  1.00 40.41  ? 222 PHE B CD1 1 
ATOM 3458 C CD2 . PHE B 2 232 ? 117.295 79.494  67.244  1.00 46.74  ? 222 PHE B CD2 1 
ATOM 3459 C CE1 . PHE B 2 232 ? 115.275 81.039  66.197  1.00 40.31  ? 222 PHE B CE1 1 
ATOM 3460 C CE2 . PHE B 2 232 ? 117.523 80.250  66.120  1.00 48.50  ? 222 PHE B CE2 1 
ATOM 3461 C CZ  . PHE B 2 232 ? 116.512 81.024  65.596  1.00 49.16  ? 222 PHE B CZ  1 
ATOM 3462 N N   . THR B 2 233 ? 115.655 75.471  70.350  1.00 46.80  ? 223 THR B N   1 
ATOM 3463 C CA  . THR B 2 233 ? 115.497 74.689  71.563  1.00 53.93  ? 223 THR B CA  1 
ATOM 3464 C C   . THR B 2 233 ? 116.817 74.648  72.322  1.00 57.15  ? 223 THR B C   1 
ATOM 3465 O O   . THR B 2 233 ? 117.861 75.081  71.830  1.00 53.55  ? 223 THR B O   1 
ATOM 3466 C CB  . THR B 2 233 ? 115.020 73.266  71.251  1.00 51.83  ? 223 THR B CB  1 
ATOM 3467 O OG1 . THR B 2 233 ? 115.940 72.640  70.349  1.00 59.43  ? 223 THR B OG1 1 
ATOM 3468 C CG2 . THR B 2 233 ? 113.638 73.294  70.620  1.00 49.26  ? 223 THR B CG2 1 
ATOM 3469 N N   . GLY B 2 234 ? 116.756 74.118  73.538  1.00 54.39  ? 224 GLY B N   1 
ATOM 3470 C CA  . GLY B 2 234 ? 117.929 74.035  74.382  1.00 50.40  ? 224 GLY B CA  1 
ATOM 3471 C C   . GLY B 2 234 ? 117.640 74.310  75.840  1.00 50.01  ? 224 GLY B C   1 
ATOM 3472 O O   . GLY B 2 234 ? 118.350 73.814  76.719  1.00 56.42  ? 224 GLY B O   1 
ATOM 3473 N N   . HIS B 2 235 ? 116.594 75.079  76.118  1.00 47.67  ? 225 HIS B N   1 
ATOM 3474 C CA  . HIS B 2 235 ? 116.176 75.277  77.495  1.00 46.85  ? 225 HIS B CA  1 
ATOM 3475 C C   . HIS B 2 235 ? 115.515 74.014  78.033  1.00 51.77  ? 225 HIS B C   1 
ATOM 3476 O O   . HIS B 2 235 ? 114.972 73.201  77.282  1.00 54.49  ? 225 HIS B O   1 
ATOM 3477 C CB  . HIS B 2 235 ? 115.219 76.460  77.605  1.00 40.15  ? 225 HIS B CB  1 
ATOM 3478 C CG  . HIS B 2 235 ? 115.901 77.791  77.620  1.00 47.27  ? 225 HIS B CG  1 
ATOM 3479 N ND1 . HIS B 2 235 ? 116.734 78.188  78.642  1.00 45.59  ? 225 HIS B ND1 1 
ATOM 3480 C CD2 . HIS B 2 235 ? 115.863 78.822  76.745  1.00 51.30  ? 225 HIS B CD2 1 
ATOM 3481 C CE1 . HIS B 2 235 ? 117.183 79.404  78.395  1.00 39.46  ? 225 HIS B CE1 1 
ATOM 3482 N NE2 . HIS B 2 235 ? 116.671 79.812  77.249  1.00 44.24  ? 225 HIS B NE2 1 
ATOM 3483 N N   . GLU B 2 236 ? 115.562 73.858  79.354  1.00 52.78  ? 226 GLU B N   1 
ATOM 3484 C CA  . GLU B 2 236 ? 114.994 72.693  80.014  1.00 50.71  ? 226 GLU B CA  1 
ATOM 3485 C C   . GLU B 2 236 ? 113.659 72.973  80.686  1.00 52.40  ? 226 GLU B C   1 
ATOM 3486 O O   . GLU B 2 236 ? 113.021 72.035  81.172  1.00 58.66  ? 226 GLU B O   1 
ATOM 3487 C CB  . GLU B 2 236 ? 115.979 72.146  81.053  1.00 49.95  ? 226 GLU B CB  1 
ATOM 3488 C CG  . GLU B 2 236 ? 117.332 71.778  80.475  1.00 55.86  ? 226 GLU B CG  1 
ATOM 3489 C CD  . GLU B 2 236 ? 118.330 71.385  81.541  1.00 68.03  ? 226 GLU B CD  1 
ATOM 3490 O OE1 . GLU B 2 236 ? 117.967 71.412  82.736  1.00 66.24  ? 226 GLU B OE1 1 
ATOM 3491 O OE2 . GLU B 2 236 ? 119.480 71.050  81.185  1.00 68.18  ? 226 GLU B OE2 1 
ATOM 3492 N N   . SER B 2 237 ? 113.224 74.228  80.728  1.00 37.03  ? 227 SER B N   1 
ATOM 3493 C CA  . SER B 2 237 ? 111.955 74.582  81.342  1.00 34.50  ? 227 SER B CA  1 
ATOM 3494 C C   . SER B 2 237 ? 111.342 75.736  80.560  1.00 39.06  ? 227 SER B C   1 
ATOM 3495 O O   . SER B 2 237 ? 111.867 76.162  79.528  1.00 41.49  ? 227 SER B O   1 
ATOM 3496 C CB  . SER B 2 237 ? 112.136 74.922  82.822  1.00 46.86  ? 227 SER B CB  1 
ATOM 3497 O OG  . SER B 2 237 ? 113.112 75.930  82.996  1.00 57.53  ? 227 SER B OG  1 
ATOM 3498 N N   . ASP B 2 238 ? 110.213 76.232  81.062  1.00 46.93  ? 228 ASP B N   1 
ATOM 3499 C CA  . ASP B 2 238 ? 109.469 77.279  80.376  1.00 42.58  ? 228 ASP B CA  1 
ATOM 3500 C C   . ASP B 2 238 ? 110.327 78.515  80.152  1.00 47.70  ? 228 ASP B C   1 
ATOM 3501 O O   . ASP B 2 238 ? 111.052 78.960  81.044  1.00 55.11  ? 228 ASP B O   1 
ATOM 3502 C CB  . ASP B 2 238 ? 108.233 77.656  81.189  1.00 43.29  ? 228 ASP B CB  1 
ATOM 3503 C CG  . ASP B 2 238 ? 107.483 76.448  81.692  1.00 60.76  ? 228 ASP B CG  1 
ATOM 3504 O OD1 . ASP B 2 238 ? 107.917 75.316  81.395  1.00 61.05  ? 228 ASP B OD1 1 
ATOM 3505 O OD2 . ASP B 2 238 ? 106.462 76.629  82.386  1.00 61.81  ? 228 ASP B OD2 1 
ATOM 3506 N N   . ILE B 2 239 ? 110.236 79.072  78.950  1.00 45.21  ? 229 ILE B N   1 
ATOM 3507 C CA  . ILE B 2 239 ? 110.876 80.344  78.645  1.00 39.33  ? 229 ILE B CA  1 
ATOM 3508 C C   . ILE B 2 239 ? 109.958 81.472  79.091  1.00 38.38  ? 229 ILE B C   1 
ATOM 3509 O O   . ILE B 2 239 ? 108.782 81.519  78.715  1.00 37.97  ? 229 ILE B O   1 
ATOM 3510 C CB  . ILE B 2 239 ? 111.204 80.445  77.149  1.00 44.10  ? 229 ILE B CB  1 
ATOM 3511 C CG1 . ILE B 2 239 ? 112.244 79.394  76.765  1.00 35.59  ? 229 ILE B CG1 1 
ATOM 3512 C CG2 . ILE B 2 239 ? 111.694 81.836  76.803  1.00 48.05  ? 229 ILE B CG2 1 
ATOM 3513 C CD1 . ILE B 2 239 ? 112.626 79.428  75.315  1.00 39.14  ? 229 ILE B CD1 1 
ATOM 3514 N N   . ASN B 2 240 ? 110.495 82.389  79.898  1.00 42.38  ? 230 ASN B N   1 
ATOM 3515 C CA  . ASN B 2 240 ? 109.717 83.488  80.445  1.00 36.85  ? 230 ASN B CA  1 
ATOM 3516 C C   . ASN B 2 240 ? 110.021 84.832  79.807  1.00 45.23  ? 230 ASN B C   1 
ATOM 3517 O O   . ASN B 2 240 ? 109.192 85.740  79.899  1.00 50.92  ? 230 ASN B O   1 
ATOM 3518 C CB  . ASN B 2 240 ? 109.949 83.604  81.957  1.00 32.93  ? 230 ASN B CB  1 
ATOM 3519 C CG  . ASN B 2 240 ? 109.502 82.375  82.710  1.00 48.32  ? 230 ASN B CG  1 
ATOM 3520 O OD1 . ASN B 2 240 ? 108.481 81.770  82.387  1.00 53.73  ? 230 ASN B OD1 1 
ATOM 3521 N ND2 . ASN B 2 240 ? 110.269 81.994  83.722  1.00 42.35  ? 230 ASN B ND2 1 
ATOM 3522 N N   . ALA B 2 241 ? 111.183 84.985  79.181  1.00 42.38  ? 231 ALA B N   1 
ATOM 3523 C CA  . ALA B 2 241 ? 111.598 86.272  78.654  1.00 25.25  ? 231 ALA B CA  1 
ATOM 3524 C C   . ALA B 2 241 ? 112.387 86.063  77.374  1.00 36.92  ? 231 ALA B C   1 
ATOM 3525 O O   . ALA B 2 241 ? 113.013 85.020  77.175  1.00 39.34  ? 231 ALA B O   1 
ATOM 3526 C CB  . ALA B 2 241 ? 112.440 87.042  79.667  1.00 37.22  ? 231 ALA B CB  1 
ATOM 3527 N N   . ILE B 2 242 ? 112.350 87.071  76.510  1.00 37.36  ? 232 ILE B N   1 
ATOM 3528 C CA  . ILE B 2 242 ? 113.043 87.019  75.231  1.00 31.59  ? 232 ILE B CA  1 
ATOM 3529 C C   . ILE B 2 242 ? 113.269 88.454  74.778  1.00 44.05  ? 232 ILE B C   1 
ATOM 3530 O O   . ILE B 2 242 ? 112.447 89.338  75.035  1.00 43.98  ? 232 ILE B O   1 
ATOM 3531 C CB  . ILE B 2 242 ? 112.253 86.177  74.199  1.00 34.40  ? 232 ILE B CB  1 
ATOM 3532 C CG1 . ILE B 2 242 ? 113.159 85.731  73.053  1.00 40.13  ? 232 ILE B CG1 1 
ATOM 3533 C CG2 . ILE B 2 242 ? 111.053 86.933  73.671  1.00 31.60  ? 232 ILE B CG2 1 
ATOM 3534 C CD1 . ILE B 2 242 ? 112.605 84.570  72.283  1.00 39.37  ? 232 ILE B CD1 1 
ATOM 3535 N N   . CYS B 2 243 ? 114.405 88.688  74.129  1.00 39.22  ? 233 CYS B N   1 
ATOM 3536 C CA  . CYS B 2 243 ? 114.782 90.035  73.725  1.00 30.80  ? 233 CYS B CA  1 
ATOM 3537 C C   . CYS B 2 243 ? 115.717 89.950  72.531  1.00 38.02  ? 233 CYS B C   1 
ATOM 3538 O O   . CYS B 2 243 ? 116.665 89.163  72.540  1.00 46.03  ? 233 CYS B O   1 
ATOM 3539 C CB  . CYS B 2 243 ? 115.456 90.788  74.877  1.00 38.67  ? 233 CYS B CB  1 
ATOM 3540 S SG  . CYS B 2 243 ? 115.837 92.516  74.525  1.00 51.06  ? 233 CYS B SG  1 
ATOM 3541 N N   . PHE B 2 244 ? 115.435 90.746  71.505  1.00 34.03  ? 234 PHE B N   1 
ATOM 3542 C CA  . PHE B 2 244 ? 116.285 90.778  70.325  1.00 33.16  ? 234 PHE B CA  1 
ATOM 3543 C C   . PHE B 2 244 ? 117.600 91.498  70.600  1.00 33.20  ? 234 PHE B C   1 
ATOM 3544 O O   . PHE B 2 244 ? 117.652 92.473  71.352  1.00 39.22  ? 234 PHE B O   1 
ATOM 3545 C CB  . PHE B 2 244 ? 115.556 91.461  69.172  1.00 26.61  ? 234 PHE B CB  1 
ATOM 3546 C CG  . PHE B 2 244 ? 115.115 90.522  68.093  1.00 32.27  ? 234 PHE B CG  1 
ATOM 3547 C CD1 . PHE B 2 244 ? 116.024 90.021  67.181  1.00 45.75  ? 234 PHE B CD1 1 
ATOM 3548 C CD2 . PHE B 2 244 ? 113.791 90.147  67.983  1.00 28.70  ? 234 PHE B CD2 1 
ATOM 3549 C CE1 . PHE B 2 244 ? 115.621 89.160  66.184  1.00 41.51  ? 234 PHE B CE1 1 
ATOM 3550 C CE2 . PHE B 2 244 ? 113.384 89.290  66.988  1.00 34.94  ? 234 PHE B CE2 1 
ATOM 3551 C CZ  . PHE B 2 244 ? 114.300 88.796  66.088  1.00 37.67  ? 234 PHE B CZ  1 
ATOM 3552 N N   . PHE B 2 245 ? 118.666 91.006  69.976  1.00 43.68  ? 235 PHE B N   1 
ATOM 3553 C CA  . PHE B 2 245 ? 119.930 91.721  69.954  1.00 40.97  ? 235 PHE B CA  1 
ATOM 3554 C C   . PHE B 2 245 ? 119.785 92.992  69.117  1.00 51.59  ? 235 PHE B C   1 
ATOM 3555 O O   . PHE B 2 245 ? 118.987 93.035  68.178  1.00 53.70  ? 235 PHE B O   1 
ATOM 3556 C CB  . PHE B 2 245 ? 121.032 90.833  69.379  1.00 40.27  ? 235 PHE B CB  1 
ATOM 3557 C CG  . PHE B 2 245 ? 122.420 91.249  69.769  1.00 45.59  ? 235 PHE B CG  1 
ATOM 3558 C CD1 . PHE B 2 245 ? 122.910 90.973  71.029  1.00 49.93  ? 235 PHE B CD1 1 
ATOM 3559 C CD2 . PHE B 2 245 ? 123.237 91.914  68.872  1.00 46.75  ? 235 PHE B CD2 1 
ATOM 3560 C CE1 . PHE B 2 245 ? 124.187 91.354  71.387  1.00 51.64  ? 235 PHE B CE1 1 
ATOM 3561 C CE2 . PHE B 2 245 ? 124.512 92.298  69.225  1.00 43.11  ? 235 PHE B CE2 1 
ATOM 3562 C CZ  . PHE B 2 245 ? 124.987 92.018  70.483  1.00 46.34  ? 235 PHE B CZ  1 
ATOM 3563 N N   . PRO B 2 246 ? 120.532 94.050  69.450  1.00 49.40  ? 236 PRO B N   1 
ATOM 3564 C CA  . PRO B 2 246 ? 120.312 95.340  68.776  1.00 49.65  ? 236 PRO B CA  1 
ATOM 3565 C C   . PRO B 2 246 ? 120.448 95.300  67.262  1.00 52.13  ? 236 PRO B C   1 
ATOM 3566 O O   . PRO B 2 246 ? 119.840 96.136  66.583  1.00 59.23  ? 236 PRO B O   1 
ATOM 3567 C CB  . PRO B 2 246 ? 121.380 96.237  69.412  1.00 46.96  ? 236 PRO B CB  1 
ATOM 3568 C CG  . PRO B 2 246 ? 121.529 95.693  70.776  1.00 48.31  ? 236 PRO B CG  1 
ATOM 3569 C CD  . PRO B 2 246 ? 121.363 94.205  70.656  1.00 47.41  ? 236 PRO B CD  1 
ATOM 3570 N N   . ASN B 2 247 ? 121.221 94.373  66.702  1.00 46.49  ? 237 ASN B N   1 
ATOM 3571 C CA  . ASN B 2 247 ? 121.318 94.288  65.251  1.00 46.67  ? 237 ASN B CA  1 
ATOM 3572 C C   . ASN B 2 247 ? 120.269 93.378  64.628  1.00 51.39  ? 237 ASN B C   1 
ATOM 3573 O O   . ASN B 2 247 ? 120.183 93.313  63.398  1.00 56.01  ? 237 ASN B O   1 
ATOM 3574 C CB  . ASN B 2 247 ? 122.714 93.806  64.835  1.00 48.71  ? 237 ASN B CB  1 
ATOM 3575 C CG  . ASN B 2 247 ? 123.065 92.451  65.414  1.00 52.66  ? 237 ASN B CG  1 
ATOM 3576 O OD1 . ASN B 2 247 ? 122.230 91.780  66.014  1.00 55.99  ? 237 ASN B OD1 1 
ATOM 3577 N ND2 . ASN B 2 247 ? 124.310 92.036  65.226  1.00 52.38  ? 237 ASN B ND2 1 
ATOM 3578 N N   . GLY B 2 248 ? 119.473 92.682  65.435  1.00 49.29  ? 238 GLY B N   1 
ATOM 3579 C CA  . GLY B 2 248 ? 118.422 91.835  64.918  1.00 48.35  ? 238 GLY B CA  1 
ATOM 3580 C C   . GLY B 2 248 ? 118.867 90.462  64.472  1.00 49.10  ? 238 GLY B C   1 
ATOM 3581 O O   . GLY B 2 248 ? 118.033 89.686  63.994  1.00 52.72  ? 238 GLY B O   1 
ATOM 3582 N N   . ASN B 2 249 ? 120.152 90.140  64.599  1.00 56.14  ? 239 ASN B N   1 
ATOM 3583 C CA  . ASN B 2 249 ? 120.694 88.862  64.162  1.00 50.55  ? 239 ASN B CA  1 
ATOM 3584 C C   . ASN B 2 249 ? 120.815 87.852  65.292  1.00 48.28  ? 239 ASN B C   1 
ATOM 3585 O O   . ASN B 2 249 ? 121.316 86.748  65.065  1.00 54.02  ? 239 ASN B O   1 
ATOM 3586 C CB  . ASN B 2 249 ? 122.062 89.067  63.505  1.00 51.45  ? 239 ASN B CB  1 
ATOM 3587 C CG  . ASN B 2 249 ? 121.977 89.865  62.223  1.00 54.33  ? 239 ASN B CG  1 
ATOM 3588 O OD1 . ASN B 2 249 ? 121.019 89.738  61.463  1.00 55.16  ? 239 ASN B OD1 1 
ATOM 3589 N ND2 . ASN B 2 249 ? 122.976 90.701  61.979  1.00 53.07  ? 239 ASN B ND2 1 
ATOM 3590 N N   . ALA B 2 250 ? 120.376 88.200  66.496  1.00 46.08  ? 240 ALA B N   1 
ATOM 3591 C CA  . ALA B 2 250 ? 120.448 87.292  67.631  1.00 33.30  ? 240 ALA B CA  1 
ATOM 3592 C C   . ALA B 2 250 ? 119.374 87.684  68.633  1.00 41.51  ? 240 ALA B C   1 
ATOM 3593 O O   . ALA B 2 250 ? 118.774 88.757  68.545  1.00 38.20  ? 240 ALA B O   1 
ATOM 3594 C CB  . ALA B 2 250 ? 121.836 87.311  68.275  1.00 32.41  ? 240 ALA B CB  1 
ATOM 3595 N N   . PHE B 2 251 ? 119.117 86.782  69.574  1.00 49.99  ? 241 PHE B N   1 
ATOM 3596 C CA  . PHE B 2 251 ? 118.205 87.066  70.670  1.00 46.15  ? 241 PHE B CA  1 
ATOM 3597 C C   . PHE B 2 251 ? 118.620 86.252  71.885  1.00 39.16  ? 241 PHE B C   1 
ATOM 3598 O O   . PHE B 2 251 ? 119.295 85.228  71.770  1.00 42.47  ? 241 PHE B O   1 
ATOM 3599 C CB  . PHE B 2 251 ? 116.750 86.777  70.283  1.00 37.47  ? 241 PHE B CB  1 
ATOM 3600 C CG  . PHE B 2 251 ? 116.468 85.331  70.023  1.00 41.96  ? 241 PHE B CG  1 
ATOM 3601 C CD1 . PHE B 2 251 ? 116.766 84.764  68.799  1.00 44.76  ? 241 PHE B CD1 1 
ATOM 3602 C CD2 . PHE B 2 251 ? 115.883 84.543  70.995  1.00 37.42  ? 241 PHE B CD2 1 
ATOM 3603 C CE1 . PHE B 2 251 ? 116.504 83.441  68.559  1.00 40.31  ? 241 PHE B CE1 1 
ATOM 3604 C CE2 . PHE B 2 251 ? 115.615 83.218  70.755  1.00 39.96  ? 241 PHE B CE2 1 
ATOM 3605 C CZ  . PHE B 2 251 ? 115.926 82.667  69.539  1.00 37.91  ? 241 PHE B CZ  1 
ATOM 3606 N N   . ALA B 2 252 ? 118.214 86.731  73.056  1.00 35.98  ? 242 ALA B N   1 
ATOM 3607 C CA  . ALA B 2 252 ? 118.476 86.056  74.316  1.00 32.81  ? 242 ALA B CA  1 
ATOM 3608 C C   . ALA B 2 252 ? 117.161 85.659  74.966  1.00 32.21  ? 242 ALA B C   1 
ATOM 3609 O O   . ALA B 2 252 ? 116.158 86.368  74.857  1.00 39.82  ? 242 ALA B O   1 
ATOM 3610 C CB  . ALA B 2 252 ? 119.279 86.940  75.270  1.00 38.27  ? 242 ALA B CB  1 
ATOM 3611 N N   . THR B 2 253 ? 117.177 84.523  75.653  1.00 31.18  ? 243 THR B N   1 
ATOM 3612 C CA  . THR B 2 253 ? 116.004 84.002  76.334  1.00 37.98  ? 243 THR B CA  1 
ATOM 3613 C C   . THR B 2 253 ? 116.307 83.824  77.813  1.00 40.23  ? 243 THR B C   1 
ATOM 3614 O O   . THR B 2 253 ? 117.460 83.677  78.217  1.00 45.30  ? 243 THR B O   1 
ATOM 3615 C CB  . THR B 2 253 ? 115.557 82.657  75.741  1.00 50.09  ? 243 THR B CB  1 
ATOM 3616 O OG1 . THR B 2 253 ? 116.613 81.701  75.879  1.00 58.37  ? 243 THR B OG1 1 
ATOM 3617 C CG2 . THR B 2 253 ? 115.206 82.798  74.274  1.00 41.95  ? 243 THR B CG2 1 
ATOM 3618 N N   . GLY B 2 254 ? 115.251 83.826  78.618  1.00 38.36  ? 244 GLY B N   1 
ATOM 3619 C CA  . GLY B 2 254 ? 115.377 83.519  80.027  1.00 40.75  ? 244 GLY B CA  1 
ATOM 3620 C C   . GLY B 2 254 ? 114.351 82.485  80.426  1.00 48.71  ? 244 GLY B C   1 
ATOM 3621 O O   . GLY B 2 254 ? 113.172 82.615  80.088  1.00 51.02  ? 244 GLY B O   1 
ATOM 3622 N N   . SER B 2 255 ? 114.776 81.457  81.145  1.00 46.24  ? 245 SER B N   1 
ATOM 3623 C CA  . SER B 2 255 ? 113.912 80.330  81.446  1.00 43.29  ? 245 SER B CA  1 
ATOM 3624 C C   . SER B 2 255 ? 113.813 80.117  82.952  1.00 42.89  ? 245 SER B C   1 
ATOM 3625 O O   . SER B 2 255 ? 114.464 80.797  83.746  1.00 51.98  ? 245 SER B O   1 
ATOM 3626 C CB  . SER B 2 255 ? 114.427 79.071  80.746  1.00 36.34  ? 245 SER B CB  1 
ATOM 3627 O OG  . SER B 2 255 ? 113.648 77.942  81.081  1.00 52.11  ? 245 SER B OG  1 
ATOM 3628 N N   . ASP B 2 256 ? 112.982 79.147  83.335  1.00 39.45  ? 246 ASP B N   1 
ATOM 3629 C CA  . ASP B 2 256 ? 112.852 78.748  84.728  1.00 43.23  ? 246 ASP B CA  1 
ATOM 3630 C C   . ASP B 2 256 ? 114.011 77.888  85.211  1.00 45.06  ? 246 ASP B C   1 
ATOM 3631 O O   . ASP B 2 256 ? 114.093 77.612  86.411  1.00 49.06  ? 246 ASP B O   1 
ATOM 3632 C CB  . ASP B 2 256 ? 111.541 77.992  84.944  1.00 44.98  ? 246 ASP B CB  1 
ATOM 3633 C CG  . ASP B 2 256 ? 110.357 78.917  85.109  1.00 57.19  ? 246 ASP B CG  1 
ATOM 3634 O OD1 . ASP B 2 256 ? 110.530 79.996  85.709  1.00 58.91  ? 246 ASP B OD1 1 
ATOM 3635 O OD2 . ASP B 2 256 ? 109.251 78.563  84.648  1.00 57.14  ? 246 ASP B OD2 1 
ATOM 3636 N N   . ASP B 2 257 ? 114.897 77.454  84.317  1.00 35.23  ? 247 ASP B N   1 
ATOM 3637 C CA  . ASP B 2 257 ? 116.052 76.656  84.697  1.00 42.14  ? 247 ASP B CA  1 
ATOM 3638 C C   . ASP B 2 257 ? 117.244 77.513  85.108  1.00 44.53  ? 247 ASP B C   1 
ATOM 3639 O O   . ASP B 2 257 ? 118.378 77.021  85.108  1.00 40.71  ? 247 ASP B O   1 
ATOM 3640 C CB  . ASP B 2 257 ? 116.438 75.702  83.563  1.00 45.84  ? 247 ASP B CB  1 
ATOM 3641 C CG  . ASP B 2 257 ? 116.706 76.417  82.258  1.00 46.19  ? 247 ASP B CG  1 
ATOM 3642 O OD1 . ASP B 2 257 ? 116.733 77.659  82.247  1.00 51.37  ? 247 ASP B OD1 1 
ATOM 3643 O OD2 . ASP B 2 257 ? 116.895 75.731  81.235  1.00 49.96  ? 247 ASP B OD2 1 
ATOM 3644 N N   . ALA B 2 258 ? 117.008 78.786  85.438  1.00 47.78  ? 248 ALA B N   1 
ATOM 3645 C CA  . ALA B 2 258 ? 118.035 79.697  85.946  1.00 43.07  ? 248 ALA B CA  1 
ATOM 3646 C C   . ALA B 2 258 ? 119.133 79.969  84.924  1.00 47.56  ? 248 ALA B C   1 
ATOM 3647 O O   . ALA B 2 258 ? 120.275 80.249  85.292  1.00 55.04  ? 248 ALA B O   1 
ATOM 3648 C CB  . ALA B 2 258 ? 118.646 79.178  87.250  1.00 44.29  ? 248 ALA B CB  1 
ATOM 3649 N N   . THR B 2 259 ? 118.811 79.895  83.635  1.00 35.94  ? 249 THR B N   1 
ATOM 3650 C CA  . THR B 2 259 ? 119.792 80.131  82.587  1.00 39.50  ? 249 THR B CA  1 
ATOM 3651 C C   . THR B 2 259 ? 119.254 81.124  81.569  1.00 48.27  ? 249 THR B C   1 
ATOM 3652 O O   . THR B 2 259 ? 118.048 81.200  81.322  1.00 50.66  ? 249 THR B O   1 
ATOM 3653 C CB  . THR B 2 259 ? 120.196 78.836  81.857  1.00 43.97  ? 249 THR B CB  1 
ATOM 3654 O OG1 . THR B 2 259 ? 119.056 78.281  81.191  1.00 42.23  ? 249 THR B OG1 1 
ATOM 3655 C CG2 . THR B 2 259 ? 120.771 77.818  82.824  1.00 39.93  ? 249 THR B CG2 1 
ATOM 3656 N N   . CYS B 2 260 ? 120.174 81.886  80.986  1.00 46.49  ? 250 CYS B N   1 
ATOM 3657 C CA  . CYS B 2 260 ? 119.916 82.717  79.823  1.00 37.13  ? 250 CYS B CA  1 
ATOM 3658 C C   . CYS B 2 260 ? 120.782 82.212  78.682  1.00 47.82  ? 250 CYS B C   1 
ATOM 3659 O O   . CYS B 2 260 ? 121.955 81.889  78.884  1.00 57.97  ? 250 CYS B O   1 
ATOM 3660 C CB  . CYS B 2 260 ? 120.236 84.192  80.094  1.00 42.45  ? 250 CYS B CB  1 
ATOM 3661 S SG  . CYS B 2 260 ? 118.957 85.141  80.925  1.00 60.01  ? 250 CYS B SG  1 
ATOM 3662 N N   . ARG B 2 261 ? 120.196 82.102  77.494  1.00 35.97  ? 251 ARG B N   1 
ATOM 3663 C CA  . ARG B 2 261 ? 120.910 81.597  76.331  1.00 34.43  ? 251 ARG B CA  1 
ATOM 3664 C C   . ARG B 2 261 ? 120.801 82.587  75.183  1.00 45.29  ? 251 ARG B C   1 
ATOM 3665 O O   . ARG B 2 261 ? 119.754 83.206  74.982  1.00 49.48  ? 251 ARG B O   1 
ATOM 3666 C CB  . ARG B 2 261 ? 120.383 80.222  75.921  1.00 43.73  ? 251 ARG B CB  1 
ATOM 3667 C CG  . ARG B 2 261 ? 120.288 79.281  77.102  1.00 48.85  ? 251 ARG B CG  1 
ATOM 3668 C CD  . ARG B 2 261 ? 120.231 77.824  76.720  1.00 46.07  ? 251 ARG B CD  1 
ATOM 3669 N NE  . ARG B 2 261 ? 120.124 77.001  77.918  1.00 49.30  ? 251 ARG B NE  1 
ATOM 3670 C CZ  . ARG B 2 261 ? 120.334 75.694  77.953  1.00 50.63  ? 251 ARG B CZ  1 
ATOM 3671 N NH1 . ARG B 2 261 ? 120.676 75.020  76.869  1.00 54.70  ? 251 ARG B NH1 1 
ATOM 3672 N NH2 . ARG B 2 261 ? 120.201 75.047  79.107  1.00 47.58  ? 251 ARG B NH2 1 
ATOM 3673 N N   . LEU B 2 262 ? 121.891 82.735  74.437  1.00 44.94  ? 252 LEU B N   1 
ATOM 3674 C CA  . LEU B 2 262 ? 121.950 83.616  73.277  1.00 43.31  ? 252 LEU B CA  1 
ATOM 3675 C C   . LEU B 2 262 ? 121.909 82.768  72.011  1.00 46.25  ? 252 LEU B C   1 
ATOM 3676 O O   . LEU B 2 262 ? 122.849 82.020  71.728  1.00 60.81  ? 252 LEU B O   1 
ATOM 3677 C CB  . LEU B 2 262 ? 123.211 84.474  73.316  1.00 47.27  ? 252 LEU B CB  1 
ATOM 3678 C CG  . LEU B 2 262 ? 123.439 85.434  72.151  1.00 44.11  ? 252 LEU B CG  1 
ATOM 3679 C CD1 . LEU B 2 262 ? 122.568 86.665  72.288  1.00 44.04  ? 252 LEU B CD1 1 
ATOM 3680 C CD2 . LEU B 2 262 ? 124.903 85.812  72.053  1.00 47.01  ? 252 LEU B CD2 1 
ATOM 3681 N N   . PHE B 2 263 ? 120.817 82.871  71.262  1.00 40.43  ? 253 PHE B N   1 
ATOM 3682 C CA  . PHE B 2 263 ? 120.662 82.169  69.997  1.00 43.84  ? 253 PHE B CA  1 
ATOM 3683 C C   . PHE B 2 263 ? 120.942 83.111  68.833  1.00 47.11  ? 253 PHE B C   1 
ATOM 3684 O O   . PHE B 2 263 ? 120.636 84.303  68.891  1.00 54.23  ? 253 PHE B O   1 
ATOM 3685 C CB  . PHE B 2 263 ? 119.254 81.589  69.853  1.00 49.04  ? 253 PHE B CB  1 
ATOM 3686 C CG  . PHE B 2 263 ? 118.838 80.704  70.990  1.00 53.42  ? 253 PHE B CG  1 
ATOM 3687 C CD1 . PHE B 2 263 ? 119.156 79.359  70.990  1.00 48.85  ? 253 PHE B CD1 1 
ATOM 3688 C CD2 . PHE B 2 263 ? 118.116 81.216  72.051  1.00 52.07  ? 253 PHE B CD2 1 
ATOM 3689 C CE1 . PHE B 2 263 ? 118.772 78.546  72.032  1.00 47.93  ? 253 PHE B CE1 1 
ATOM 3690 C CE2 . PHE B 2 263 ? 117.727 80.406  73.094  1.00 50.55  ? 253 PHE B CE2 1 
ATOM 3691 C CZ  . PHE B 2 263 ? 118.057 79.070  73.085  1.00 48.13  ? 253 PHE B CZ  1 
ATOM 3692 N N   . ASP B 2 264 ? 121.528 82.566  67.772  1.00 58.88  ? 254 ASP B N   1 
ATOM 3693 C CA  . ASP B 2 264 ? 121.798 83.316  66.554  1.00 59.12  ? 254 ASP B CA  1 
ATOM 3694 C C   . ASP B 2 264 ? 120.819 82.878  65.475  1.00 57.96  ? 254 ASP B C   1 
ATOM 3695 O O   . ASP B 2 264 ? 120.594 81.680  65.287  1.00 65.45  ? 254 ASP B O   1 
ATOM 3696 C CB  . ASP B 2 264 ? 123.235 83.110  66.076  1.00 63.75  ? 254 ASP B CB  1 
ATOM 3697 C CG  . ASP B 2 264 ? 123.642 84.113  65.012  1.00 69.73  ? 254 ASP B CG  1 
ATOM 3698 O OD1 . ASP B 2 264 ? 123.945 85.271  65.366  1.00 64.92  ? 254 ASP B OD1 1 
ATOM 3699 O OD2 . ASP B 2 264 ? 123.654 83.748  63.819  1.00 72.76  ? 254 ASP B OD2 1 
ATOM 3700 N N   . LEU B 2 265 ? 120.247 83.851  64.766  1.00 51.59  ? 255 LEU B N   1 
ATOM 3701 C CA  . LEU B 2 265 ? 119.288 83.535  63.712  1.00 54.36  ? 255 LEU B CA  1 
ATOM 3702 C C   . LEU B 2 265 ? 119.967 82.860  62.528  1.00 59.59  ? 255 LEU B C   1 
ATOM 3703 O O   . LEU B 2 265 ? 119.478 81.847  62.015  1.00 61.79  ? 255 LEU B O   1 
ATOM 3704 C CB  . LEU B 2 265 ? 118.559 84.800  63.266  1.00 53.54  ? 255 LEU B CB  1 
ATOM 3705 C CG  . LEU B 2 265 ? 117.766 85.524  64.350  1.00 59.46  ? 255 LEU B CG  1 
ATOM 3706 C CD1 . LEU B 2 265 ? 116.920 86.621  63.735  1.00 59.89  ? 255 LEU B CD1 1 
ATOM 3707 C CD2 . LEU B 2 265 ? 116.909 84.550  65.130  1.00 59.64  ? 255 LEU B CD2 1 
ATOM 3708 N N   . ARG B 2 266 ? 121.091 83.414  62.071  1.00 68.66  ? 256 ARG B N   1 
ATOM 3709 C CA  . ARG B 2 266 ? 121.720 82.912  60.854  1.00 69.46  ? 256 ARG B CA  1 
ATOM 3710 C C   . ARG B 2 266 ? 122.435 81.587  61.091  1.00 70.40  ? 256 ARG B C   1 
ATOM 3711 O O   . ARG B 2 266 ? 122.406 80.705  60.228  1.00 69.63  ? 256 ARG B O   1 
ATOM 3712 C CB  . ARG B 2 266 ? 122.690 83.955  60.303  1.00 68.42  ? 256 ARG B CB  1 
ATOM 3713 C CG  . ARG B 2 266 ? 122.012 85.221  59.818  1.00 69.79  ? 256 ARG B CG  1 
ATOM 3714 C CD  . ARG B 2 266 ? 123.026 86.249  59.363  1.00 70.72  ? 256 ARG B CD  1 
ATOM 3715 N NE  . ARG B 2 266 ? 123.880 86.682  60.461  1.00 74.40  ? 256 ARG B NE  1 
ATOM 3716 C CZ  . ARG B 2 266 ? 124.804 87.627  60.363  1.00 71.33  ? 256 ARG B CZ  1 
ATOM 3717 N NH1 . ARG B 2 266 ? 125.022 88.264  59.225  1.00 69.20  ? 256 ARG B NH1 1 
ATOM 3718 N NH2 . ARG B 2 266 ? 125.526 87.940  61.434  1.00 70.62  ? 256 ARG B NH2 1 
ATOM 3719 N N   . ALA B 2 267 ? 123.086 81.429  62.244  1.00 71.11  ? 257 ALA B N   1 
ATOM 3720 C CA  . ALA B 2 267 ? 123.666 80.139  62.595  1.00 70.41  ? 257 ALA B CA  1 
ATOM 3721 C C   . ALA B 2 267 ? 122.619 79.145  63.078  1.00 78.24  ? 257 ALA B C   1 
ATOM 3722 O O   . ALA B 2 267 ? 122.904 77.943  63.129  1.00 80.08  ? 257 ALA B O   1 
ATOM 3723 C CB  . ALA B 2 267 ? 124.745 80.314  63.664  1.00 70.90  ? 257 ALA B CB  1 
ATOM 3724 N N   . ASP B 2 268 ? 121.423 79.621  63.429  1.00 73.55  ? 258 ASP B N   1 
ATOM 3725 C CA  . ASP B 2 268 ? 120.279 78.766  63.750  1.00 67.45  ? 258 ASP B CA  1 
ATOM 3726 C C   . ASP B 2 268 ? 120.577 77.817  64.912  1.00 70.81  ? 258 ASP B C   1 
ATOM 3727 O O   . ASP B 2 268 ? 120.166 76.656  64.907  1.00 77.71  ? 258 ASP B O   1 
ATOM 3728 C CB  . ASP B 2 268 ? 119.821 77.991  62.511  1.00 70.37  ? 258 ASP B CB  1 
ATOM 3729 C CG  . ASP B 2 268 ? 118.448 77.369  62.680  1.00 79.70  ? 258 ASP B CG  1 
ATOM 3730 O OD1 . ASP B 2 268 ? 117.493 78.106  62.996  1.00 76.41  ? 258 ASP B OD1 1 
ATOM 3731 O OD2 . ASP B 2 268 ? 118.324 76.143  62.487  1.00 78.54  ? 258 ASP B OD2 1 
ATOM 3732 N N   . GLN B 2 269 ? 121.287 78.310  65.924  1.00 63.53  ? 259 GLN B N   1 
ATOM 3733 C CA  . GLN B 2 269 ? 121.617 77.484  67.078  1.00 62.52  ? 259 GLN B CA  1 
ATOM 3734 C C   . GLN B 2 269 ? 122.049 78.377  68.232  1.00 66.88  ? 259 GLN B C   1 
ATOM 3735 O O   . GLN B 2 269 ? 122.312 79.569  68.062  1.00 69.51  ? 259 GLN B O   1 
ATOM 3736 C CB  . GLN B 2 269 ? 122.704 76.457  66.748  1.00 65.76  ? 259 GLN B CB  1 
ATOM 3737 C CG  . GLN B 2 269 ? 123.955 77.038  66.134  1.00 66.96  ? 259 GLN B CG  1 
ATOM 3738 C CD  . GLN B 2 269 ? 124.973 75.970  65.805  1.00 69.07  ? 259 GLN B CD  1 
ATOM 3739 O OE1 . GLN B 2 269 ? 125.349 75.173  66.662  1.00 70.00  ? 259 GLN B OE1 1 
ATOM 3740 N NE2 . GLN B 2 269 ? 125.417 75.940  64.556  1.00 70.60  ? 259 GLN B NE2 1 
ATOM 3741 N N   . GLU B 2 270 ? 122.119 77.772  69.415  1.00 59.64  ? 260 GLU B N   1 
ATOM 3742 C CA  . GLU B 2 270 ? 122.567 78.473  70.609  1.00 60.40  ? 260 GLU B CA  1 
ATOM 3743 C C   . GLU B 2 270 ? 124.057 78.777  70.535  1.00 65.48  ? 260 GLU B C   1 
ATOM 3744 O O   . GLU B 2 270 ? 124.851 77.961  70.060  1.00 66.65  ? 260 GLU B O   1 
ATOM 3745 C CB  . GLU B 2 270 ? 122.265 77.625  71.844  1.00 58.24  ? 260 GLU B CB  1 
ATOM 3746 C CG  . GLU B 2 270 ? 122.856 78.133  73.141  1.00 63.86  ? 260 GLU B CG  1 
ATOM 3747 C CD  . GLU B 2 270 ? 122.708 77.129  74.265  1.00 66.13  ? 260 GLU B CD  1 
ATOM 3748 O OE1 . GLU B 2 270 ? 121.961 76.146  74.085  1.00 69.09  ? 260 GLU B OE1 1 
ATOM 3749 O OE2 . GLU B 2 270 ? 123.342 77.315  75.323  1.00 61.74  ? 260 GLU B OE2 1 
ATOM 3750 N N   . LEU B 2 271 ? 124.437 79.960  71.018  1.00 61.96  ? 261 LEU B N   1 
ATOM 3751 C CA  . LEU B 2 271 ? 125.833 80.374  71.037  1.00 57.37  ? 261 LEU B CA  1 
ATOM 3752 C C   . LEU B 2 271 ? 126.441 80.453  72.426  1.00 59.24  ? 261 LEU B C   1 
ATOM 3753 O O   . LEU B 2 271 ? 127.641 80.215  72.567  1.00 62.87  ? 261 LEU B O   1 
ATOM 3754 C CB  . LEU B 2 271 ? 125.995 81.744  70.367  1.00 56.96  ? 261 LEU B CB  1 
ATOM 3755 C CG  . LEU B 2 271 ? 125.624 81.872  68.893  1.00 56.58  ? 261 LEU B CG  1 
ATOM 3756 C CD1 . LEU B 2 271 ? 126.060 83.226  68.377  1.00 60.24  ? 261 LEU B CD1 1 
ATOM 3757 C CD2 . LEU B 2 271 ? 126.259 80.763  68.080  1.00 62.22  ? 261 LEU B CD2 1 
ATOM 3758 N N   . MET B 2 272 ? 125.656 80.768  73.452  1.00 57.78  ? 262 MET B N   1 
ATOM 3759 C CA  . MET B 2 272 ? 126.232 81.004  74.767  1.00 64.53  ? 262 MET B CA  1 
ATOM 3760 C C   . MET B 2 272 ? 125.152 80.868  75.827  1.00 61.87  ? 262 MET B C   1 
ATOM 3761 O O   . MET B 2 272 ? 123.991 81.210  75.596  1.00 58.46  ? 262 MET B O   1 
ATOM 3762 C CB  . MET B 2 272 ? 126.889 82.386  74.833  1.00 59.73  ? 262 MET B CB  1 
ATOM 3763 C CG  . MET B 2 272 ? 127.581 82.702  76.138  1.00 51.71  ? 262 MET B CG  1 
ATOM 3764 S SD  . MET B 2 272 ? 128.904 83.890  75.895  1.00 79.34  ? 262 MET B SD  1 
ATOM 3765 C CE  . MET B 2 272 ? 130.139 82.846  75.131  1.00 63.08  ? 262 MET B CE  1 
ATOM 3766 N N   . THR B 2 273 ? 125.556 80.375  76.995  1.00 51.13  ? 263 THR B N   1 
ATOM 3767 C CA  . THR B 2 273 ? 124.682 80.214  78.146  1.00 42.03  ? 263 THR B CA  1 
ATOM 3768 C C   . THR B 2 273 ? 125.163 81.109  79.279  1.00 47.93  ? 263 THR B C   1 
ATOM 3769 O O   . THR B 2 273 ? 126.366 81.204  79.541  1.00 53.44  ? 263 THR B O   1 
ATOM 3770 C CB  . THR B 2 273 ? 124.647 78.756  78.614  1.00 49.04  ? 263 THR B CB  1 
ATOM 3771 O OG1 . THR B 2 273 ? 124.375 77.903  77.496  1.00 56.44  ? 263 THR B OG1 1 
ATOM 3772 C CG2 . THR B 2 273 ? 123.562 78.558  79.652  1.00 50.58  ? 263 THR B CG2 1 
ATOM 3773 N N   . TYR B 2 274 ? 124.221 81.767  79.947  1.00 43.63  ? 264 TYR B N   1 
ATOM 3774 C CA  . TYR B 2 274 ? 124.511 82.710  81.025  1.00 42.31  ? 264 TYR B CA  1 
ATOM 3775 C C   . TYR B 2 274 ? 123.907 82.152  82.306  1.00 43.62  ? 264 TYR B C   1 
ATOM 3776 O O   . TYR B 2 274 ? 122.736 82.390  82.607  1.00 49.58  ? 264 TYR B O   1 
ATOM 3777 C CB  . TYR B 2 274 ? 123.969 84.098  80.707  1.00 41.06  ? 264 TYR B CB  1 
ATOM 3778 C CG  . TYR B 2 274 ? 124.400 84.619  79.359  1.00 42.73  ? 264 TYR B CG  1 
ATOM 3779 C CD1 . TYR B 2 274 ? 125.640 85.208  79.188  1.00 36.76  ? 264 TYR B CD1 1 
ATOM 3780 C CD2 . TYR B 2 274 ? 123.562 84.529  78.260  1.00 39.47  ? 264 TYR B CD2 1 
ATOM 3781 C CE1 . TYR B 2 274 ? 126.035 85.681  77.960  1.00 42.82  ? 264 TYR B CE1 1 
ATOM 3782 C CE2 . TYR B 2 274 ? 123.949 85.002  77.031  1.00 34.89  ? 264 TYR B CE2 1 
ATOM 3783 C CZ  . TYR B 2 274 ? 125.185 85.578  76.886  1.00 37.39  ? 264 TYR B CZ  1 
ATOM 3784 O OH  . TYR B 2 274 ? 125.574 86.050  75.659  1.00 44.15  ? 264 TYR B OH  1 
ATOM 3785 N N   . SER B 2 275 ? 124.710 81.409  83.062  1.00 49.39  ? 265 SER B N   1 
ATOM 3786 C CA  . SER B 2 275 ? 124.235 80.828  84.307  1.00 53.31  ? 265 SER B CA  1 
ATOM 3787 C C   . SER B 2 275 ? 125.356 80.815  85.334  1.00 53.97  ? 265 SER B C   1 
ATOM 3788 O O   . SER B 2 275 ? 126.541 80.829  84.994  1.00 58.22  ? 265 SER B O   1 
ATOM 3789 C CB  . SER B 2 275 ? 123.721 79.405  84.087  1.00 57.78  ? 265 SER B CB  1 
ATOM 3790 O OG  . SER B 2 275 ? 124.746 78.581  83.561  1.00 50.45  ? 265 SER B OG  1 
ATOM 3791 N N   . HIS B 2 276 ? 124.957 80.780  86.602  1.00 64.60  ? 266 HIS B N   1 
ATOM 3792 C CA  . HIS B 2 276 ? 125.877 80.690  87.723  1.00 65.26  ? 266 HIS B CA  1 
ATOM 3793 C C   . HIS B 2 276 ? 125.371 79.629  88.690  1.00 69.30  ? 266 HIS B C   1 
ATOM 3794 O O   . HIS B 2 276 ? 124.172 79.347  88.750  1.00 69.43  ? 266 HIS B O   1 
ATOM 3795 C CB  . HIS B 2 276 ? 126.024 82.038  88.435  1.00 63.64  ? 266 HIS B CB  1 
ATOM 3796 C CG  . HIS B 2 276 ? 127.305 82.187  89.191  1.00 69.76  ? 266 HIS B CG  1 
ATOM 3797 N ND1 . HIS B 2 276 ? 127.349 82.325  90.561  1.00 71.13  ? 266 HIS B ND1 1 
ATOM 3798 C CD2 . HIS B 2 276 ? 128.591 82.217  88.768  1.00 69.48  ? 266 HIS B CD2 1 
ATOM 3799 C CE1 . HIS B 2 276 ? 128.607 82.437  90.950  1.00 69.27  ? 266 HIS B CE1 1 
ATOM 3800 N NE2 . HIS B 2 276 ? 129.381 82.372  89.881  1.00 74.07  ? 266 HIS B NE2 1 
ATOM 3801 N N   . ASP B 2 277 ? 126.298 79.041  89.449  1.00 66.68  ? 267 ASP B N   1 
ATOM 3802 C CA  . ASP B 2 277 ? 125.919 77.976  90.374  1.00 68.97  ? 267 ASP B CA  1 
ATOM 3803 C C   . ASP B 2 277 ? 125.049 78.490  91.514  1.00 67.76  ? 267 ASP B C   1 
ATOM 3804 O O   . ASP B 2 277 ? 124.156 77.774  91.979  1.00 63.96  ? 267 ASP B O   1 
ATOM 3805 C CB  . ASP B 2 277 ? 127.169 77.296  90.928  1.00 70.09  ? 267 ASP B CB  1 
ATOM 3806 C CG  . ASP B 2 277 ? 128.000 76.638  89.847  1.00 72.22  ? 267 ASP B CG  1 
ATOM 3807 O OD1 . ASP B 2 277 ? 128.572 77.366  89.009  1.00 70.04  ? 267 ASP B OD1 1 
ATOM 3808 O OD2 . ASP B 2 277 ? 128.082 75.392  89.834  1.00 73.38  ? 267 ASP B OD2 1 
ATOM 3809 N N   . ASN B 2 278 ? 125.289 79.719  91.975  1.00 64.56  ? 268 ASN B N   1 
ATOM 3810 C CA  . ASN B 2 278 ? 124.456 80.291  93.027  1.00 62.37  ? 268 ASN B CA  1 
ATOM 3811 C C   . ASN B 2 278 ? 123.033 80.546  92.551  1.00 67.94  ? 268 ASN B C   1 
ATOM 3812 O O   . ASN B 2 278 ? 122.099 80.532  93.361  1.00 65.68  ? 268 ASN B O   1 
ATOM 3813 C CB  . ASN B 2 278 ? 125.078 81.587  93.544  1.00 60.06  ? 268 ASN B CB  1 
ATOM 3814 C CG  . ASN B 2 278 ? 126.408 81.359  94.231  1.00 66.93  ? 268 ASN B CG  1 
ATOM 3815 O OD1 . ASN B 2 278 ? 127.466 81.489  93.618  1.00 67.27  ? 268 ASN B OD1 1 
ATOM 3816 N ND2 . ASN B 2 278 ? 126.360 81.015  95.513  1.00 65.54  ? 268 ASN B ND2 1 
ATOM 3817 N N   . ILE B 2 279 ? 122.846 80.784  91.257  1.00 64.80  ? 269 ILE B N   1 
ATOM 3818 C CA  . ILE B 2 279 ? 121.533 81.126  90.721  1.00 57.64  ? 269 ILE B CA  1 
ATOM 3819 C C   . ILE B 2 279 ? 120.745 79.842  90.496  1.00 57.05  ? 269 ILE B C   1 
ATOM 3820 O O   . ILE B 2 279 ? 121.133 78.998  89.682  1.00 56.92  ? 269 ILE B O   1 
ATOM 3821 C CB  . ILE B 2 279 ? 121.666 81.929  89.421  1.00 56.89  ? 269 ILE B CB  1 
ATOM 3822 C CG1 . ILE B 2 279 ? 122.590 83.128  89.633  1.00 56.96  ? 269 ILE B CG1 1 
ATOM 3823 C CG2 . ILE B 2 279 ? 120.308 82.397  88.949  1.00 55.24  ? 269 ILE B CG2 1 
ATOM 3824 C CD1 . ILE B 2 279 ? 122.895 83.892  88.370  1.00 54.02  ? 269 ILE B CD1 1 
ATOM 3825 N N   . ILE B 2 280 ? 119.636 79.692  91.218  1.00 57.89  ? 270 ILE B N   1 
ATOM 3826 C CA  . ILE B 2 280 ? 118.800 78.501  91.112  1.00 58.48  ? 270 ILE B CA  1 
ATOM 3827 C C   . ILE B 2 280 ? 117.350 78.913  90.905  1.00 59.43  ? 270 ILE B C   1 
ATOM 3828 O O   . ILE B 2 280 ? 116.447 78.070  90.908  1.00 58.00  ? 270 ILE B O   1 
ATOM 3829 C CB  . ILE B 2 280 ? 118.940 77.603  92.354  1.00 54.93  ? 270 ILE B CB  1 
ATOM 3830 C CG1 . ILE B 2 280 ? 118.604 78.391  93.620  1.00 52.88  ? 270 ILE B CG1 1 
ATOM 3831 C CG2 . ILE B 2 280 ? 120.339 77.015  92.435  1.00 55.43  ? 270 ILE B CG2 1 
ATOM 3832 C CD1 . ILE B 2 280 ? 118.700 77.579  94.888  1.00 51.76  ? 270 ILE B CD1 1 
ATOM 3833 N N   . CYS B 2 281 ? 117.117 80.206  90.722  1.00 57.61  ? 271 CYS B N   1 
ATOM 3834 C CA  . CYS B 2 281 ? 115.773 80.740  90.578  1.00 55.84  ? 271 CYS B CA  1 
ATOM 3835 C C   . CYS B 2 281 ? 115.478 81.051  89.116  1.00 56.02  ? 271 CYS B C   1 
ATOM 3836 O O   . CYS B 2 281 ? 116.379 81.182  88.286  1.00 58.54  ? 271 CYS B O   1 
ATOM 3837 C CB  . CYS B 2 281 ? 115.595 81.999  91.428  1.00 52.46  ? 271 CYS B CB  1 
ATOM 3838 S SG  . CYS B 2 281 ? 116.641 83.377  90.934  1.00 65.20  ? 271 CYS B SG  1 
ATOM 3839 N N   . GLY B 2 282 ? 114.192 81.168  88.810  1.00 46.72  ? 272 GLY B N   1 
ATOM 3840 C CA  . GLY B 2 282 ? 113.784 81.456  87.455  1.00 41.12  ? 272 GLY B CA  1 
ATOM 3841 C C   . GLY B 2 282 ? 114.093 82.881  87.045  1.00 40.82  ? 272 GLY B C   1 
ATOM 3842 O O   . GLY B 2 282 ? 114.324 83.769  87.863  1.00 43.65  ? 272 GLY B O   1 
ATOM 3843 N N   . ILE B 2 283 ? 114.114 83.091  85.733  1.00 37.14  ? 273 ILE B N   1 
ATOM 3844 C CA  . ILE B 2 283 ? 114.383 84.390  85.133  1.00 32.03  ? 273 ILE B CA  1 
ATOM 3845 C C   . ILE B 2 283 ? 113.073 84.933  84.585  1.00 37.90  ? 273 ILE B C   1 
ATOM 3846 O O   . ILE B 2 283 ? 112.324 84.209  83.921  1.00 48.15  ? 273 ILE B O   1 
ATOM 3847 C CB  . ILE B 2 283 ? 115.453 84.276  84.039  1.00 33.93  ? 273 ILE B CB  1 
ATOM 3848 C CG1 . ILE B 2 283 ? 116.681 83.588  84.625  1.00 39.96  ? 273 ILE B CG1 1 
ATOM 3849 C CG2 . ILE B 2 283 ? 115.806 85.638  83.482  1.00 33.27  ? 273 ILE B CG2 1 
ATOM 3850 C CD1 . ILE B 2 283 ? 117.809 83.450  83.682  1.00 49.99  ? 273 ILE B CD1 1 
ATOM 3851 N N   . THR B 2 284 ? 112.797 86.205  84.863  1.00 37.36  ? 274 THR B N   1 
ATOM 3852 C CA  . THR B 2 284 ? 111.527 86.823  84.509  1.00 30.67  ? 274 THR B CA  1 
ATOM 3853 C C   . THR B 2 284 ? 111.613 87.768  83.325  1.00 35.78  ? 274 THR B C   1 
ATOM 3854 O O   . THR B 2 284 ? 110.644 87.887  82.576  1.00 46.00  ? 274 THR B O   1 
ATOM 3855 C CB  . THR B 2 284 ? 110.959 87.591  85.707  1.00 36.88  ? 274 THR B CB  1 
ATOM 3856 O OG1 . THR B 2 284 ? 111.937 88.517  86.188  1.00 47.90  ? 274 THR B OG1 1 
ATOM 3857 C CG2 . THR B 2 284 ? 110.599 86.637  86.819  1.00 37.55  ? 274 THR B CG2 1 
ATOM 3858 N N   . SER B 2 285 ? 112.742 88.443  83.141  1.00 37.61  ? 275 SER B N   1 
ATOM 3859 C CA  . SER B 2 285 ? 112.872 89.464  82.116  1.00 22.58  ? 275 SER B CA  1 
ATOM 3860 C C   . SER B 2 285 ? 114.324 89.533  81.670  1.00 33.08  ? 275 SER B C   1 
ATOM 3861 O O   . SER B 2 285 ? 115.238 89.262  82.449  1.00 44.30  ? 275 SER B O   1 
ATOM 3862 C CB  . SER B 2 285 ? 112.397 90.822  82.628  1.00 29.72  ? 275 SER B CB  1 
ATOM 3863 O OG  . SER B 2 285 ? 113.050 91.145  83.839  1.00 43.67  ? 275 SER B OG  1 
ATOM 3864 N N   . VAL B 2 286 ? 114.523 89.869  80.397  1.00 29.14  ? 276 VAL B N   1 
ATOM 3865 C CA  . VAL B 2 286 ? 115.852 90.023  79.820  1.00 27.66  ? 276 VAL B CA  1 
ATOM 3866 C C   . VAL B 2 286 ? 115.840 91.240  78.910  1.00 35.31  ? 276 VAL B C   1 
ATOM 3867 O O   . VAL B 2 286 ? 114.818 91.582  78.310  1.00 48.56  ? 276 VAL B O   1 
ATOM 3868 C CB  . VAL B 2 286 ? 116.330 88.783  79.026  1.00 26.14  ? 276 VAL B CB  1 
ATOM 3869 C CG1 . VAL B 2 286 ? 116.532 87.594  79.939  1.00 33.63  ? 276 VAL B CG1 1 
ATOM 3870 C CG2 . VAL B 2 286 ? 115.361 88.452  77.916  1.00 31.61  ? 276 VAL B CG2 1 
ATOM 3871 N N   . SER B 2 287 ? 116.986 91.906  78.825  1.00 28.06  ? 277 SER B N   1 
ATOM 3872 C CA  . SER B 2 287 ? 117.135 93.041  77.929  1.00 29.42  ? 277 SER B CA  1 
ATOM 3873 C C   . SER B 2 287 ? 118.612 93.222  77.629  1.00 30.99  ? 277 SER B C   1 
ATOM 3874 O O   . SER B 2 287 ? 119.475 92.744  78.366  1.00 40.91  ? 277 SER B O   1 
ATOM 3875 C CB  . SER B 2 287 ? 116.543 94.319  78.527  1.00 31.04  ? 277 SER B CB  1 
ATOM 3876 O OG  . SER B 2 287 ? 116.630 95.392  77.610  1.00 45.19  ? 277 SER B OG  1 
ATOM 3877 N N   . PHE B 2 288 ? 118.889 93.932  76.545  1.00 26.06  ? 278 PHE B N   1 
ATOM 3878 C CA  . PHE B 2 288 ? 120.251 94.230  76.137  1.00 37.83  ? 278 PHE B CA  1 
ATOM 3879 C C   . PHE B 2 288 ? 120.530 95.718  76.283  1.00 46.38  ? 278 PHE B C   1 
ATOM 3880 O O   . PHE B 2 288 ? 119.628 96.552  76.177  1.00 53.66  ? 278 PHE B O   1 
ATOM 3881 C CB  . PHE B 2 288 ? 120.500 93.803  74.688  1.00 39.70  ? 278 PHE B CB  1 
ATOM 3882 C CG  . PHE B 2 288 ? 120.826 92.347  74.528  1.00 32.81  ? 278 PHE B CG  1 
ATOM 3883 C CD1 . PHE B 2 288 ? 122.063 91.860  74.900  1.00 36.27  ? 278 PHE B CD1 1 
ATOM 3884 C CD2 . PHE B 2 288 ? 119.906 91.474  73.986  1.00 36.72  ? 278 PHE B CD2 1 
ATOM 3885 C CE1 . PHE B 2 288 ? 122.369 90.529  74.752  1.00 33.09  ? 278 PHE B CE1 1 
ATOM 3886 C CE2 . PHE B 2 288 ? 120.211 90.141  73.830  1.00 42.97  ? 278 PHE B CE2 1 
ATOM 3887 C CZ  . PHE B 2 288 ? 121.444 89.669  74.213  1.00 36.65  ? 278 PHE B CZ  1 
ATOM 3888 N N   . SER B 2 289 ? 121.796 96.044  76.520  1.00 42.48  ? 279 SER B N   1 
ATOM 3889 C CA  . SER B 2 289 ? 122.225 97.427  76.450  1.00 44.94  ? 279 SER B CA  1 
ATOM 3890 C C   . SER B 2 289 ? 122.277 97.881  74.994  1.00 53.76  ? 279 SER B C   1 
ATOM 3891 O O   . SER B 2 289 ? 122.113 97.093  74.059  1.00 47.79  ? 279 SER B O   1 
ATOM 3892 C CB  . SER B 2 289 ? 123.583 97.607  77.122  1.00 41.52  ? 279 SER B CB  1 
ATOM 3893 O OG  . SER B 2 289 ? 124.576 96.830  76.484  1.00 55.51  ? 279 SER B OG  1 
ATOM 3894 N N   . LYS B 2 290 ? 122.505 99.182  74.810  1.00 50.17  ? 280 LYS B N   1 
ATOM 3895 C CA  . LYS B 2 290 ? 122.388 99.774  73.482  1.00 45.91  ? 280 LYS B CA  1 
ATOM 3896 C C   . LYS B 2 290 ? 123.373 99.150  72.502  1.00 51.00  ? 280 LYS B C   1 
ATOM 3897 O O   . LYS B 2 290 ? 123.026 98.895  71.343  1.00 55.50  ? 280 LYS B O   1 
ATOM 3898 C CB  . LYS B 2 290 ? 122.594 101.285 73.562  1.00 51.78  ? 280 LYS B CB  1 
ATOM 3899 C CG  . LYS B 2 290 ? 122.408 101.987 72.234  1.00 52.85  ? 280 LYS B CG  1 
ATOM 3900 C CD  . LYS B 2 290 ? 122.585 103.481 72.357  1.00 50.68  ? 280 LYS B CD  1 
ATOM 3901 C CE  . LYS B 2 290 ? 122.384 104.152 71.015  1.00 50.29  ? 280 LYS B CE  1 
ATOM 3902 N NZ  . LYS B 2 290 ? 121.048 103.836 70.447  1.00 48.23  ? 280 LYS B NZ  1 
ATOM 3903 N N   . SER B 2 291 ? 124.604 98.899  72.942  1.00 43.56  ? 281 SER B N   1 
ATOM 3904 C CA  . SER B 2 291 ? 125.591 98.237  72.101  1.00 47.52  ? 281 SER B CA  1 
ATOM 3905 C C   . SER B 2 291 ? 125.450 96.723  72.078  1.00 52.14  ? 281 SER B C   1 
ATOM 3906 O O   . SER B 2 291 ? 126.109 96.072  71.263  1.00 47.05  ? 281 SER B O   1 
ATOM 3907 C CB  . SER B 2 291 ? 126.999 98.591  72.571  1.00 50.57  ? 281 SER B CB  1 
ATOM 3908 O OG  . SER B 2 291 ? 127.198 98.183  73.911  1.00 59.75  ? 281 SER B OG  1 
ATOM 3909 N N   . GLY B 2 292 ? 124.619 96.150  72.943  1.00 51.15  ? 282 GLY B N   1 
ATOM 3910 C CA  . GLY B 2 292 ? 124.481 94.715  73.033  1.00 47.90  ? 282 GLY B CA  1 
ATOM 3911 C C   . GLY B 2 292 ? 125.551 94.024  73.847  1.00 49.40  ? 282 GLY B C   1 
ATOM 3912 O O   . GLY B 2 292 ? 125.513 92.795  73.970  1.00 53.77  ? 282 GLY B O   1 
ATOM 3913 N N   . ARG B 2 293 ? 126.515 94.769  74.391  1.00 50.82  ? 283 ARG B N   1 
ATOM 3914 C CA  . ARG B 2 293 ? 127.579 94.148  75.170  1.00 41.34  ? 283 ARG B CA  1 
ATOM 3915 C C   . ARG B 2 293 ? 127.075 93.661  76.520  1.00 41.11  ? 283 ARG B C   1 
ATOM 3916 O O   . ARG B 2 293 ? 127.626 92.706  77.075  1.00 59.89  ? 283 ARG B O   1 
ATOM 3917 C CB  . ARG B 2 293 ? 128.741 95.125  75.353  1.00 48.14  ? 283 ARG B CB  1 
ATOM 3918 C CG  . ARG B 2 293 ? 129.924 94.557  76.123  1.00 37.47  ? 283 ARG B CG  1 
ATOM 3919 C CD  . ARG B 2 293 ? 130.441 93.281  75.493  1.00 44.32  ? 283 ARG B CD  1 
ATOM 3920 N NE  . ARG B 2 293 ? 131.477 92.649  76.301  1.00 46.68  ? 283 ARG B NE  1 
ATOM 3921 C CZ  . ARG B 2 293 ? 132.779 92.832  76.130  1.00 49.43  ? 283 ARG B CZ  1 
ATOM 3922 N NH1 . ARG B 2 293 ? 133.247 93.625  75.182  1.00 50.89  ? 283 ARG B NH1 1 
ATOM 3923 N NH2 . ARG B 2 293 ? 133.632 92.201  76.930  1.00 50.81  ? 283 ARG B NH2 1 
ATOM 3924 N N   . LEU B 2 294 ? 126.038 94.291  77.062  1.00 28.00  ? 284 LEU B N   1 
ATOM 3925 C CA  . LEU B 2 294 ? 125.481 93.913  78.352  1.00 32.60  ? 284 LEU B CA  1 
ATOM 3926 C C   . LEU B 2 294 ? 124.121 93.260  78.168  1.00 35.40  ? 284 LEU B C   1 
ATOM 3927 O O   . LEU B 2 294 ? 123.285 93.758  77.409  1.00 46.90  ? 284 LEU B O   1 
ATOM 3928 C CB  . LEU B 2 294 ? 125.351 95.128  79.271  1.00 37.84  ? 284 LEU B CB  1 
ATOM 3929 C CG  . LEU B 2 294 ? 126.633 95.879  79.623  1.00 43.69  ? 284 LEU B CG  1 
ATOM 3930 C CD1 . LEU B 2 294 ? 126.315 97.043  80.536  1.00 41.46  ? 284 LEU B CD1 1 
ATOM 3931 C CD2 . LEU B 2 294 ? 127.643 94.946  80.266  1.00 37.44  ? 284 LEU B CD2 1 
ATOM 3932 N N   . LEU B 2 295 ? 123.908 92.149  78.865  1.00 35.11  ? 285 LEU B N   1 
ATOM 3933 C CA  . LEU B 2 295 ? 122.617 91.475  78.939  1.00 32.69  ? 285 LEU B CA  1 
ATOM 3934 C C   . LEU B 2 295 ? 122.120 91.567  80.375  1.00 31.65  ? 285 LEU B C   1 
ATOM 3935 O O   . LEU B 2 295 ? 122.733 91.001  81.286  1.00 40.99  ? 285 LEU B O   1 
ATOM 3936 C CB  . LEU B 2 295 ? 122.732 90.023  78.483  1.00 40.92  ? 285 LEU B CB  1 
ATOM 3937 C CG  . LEU B 2 295 ? 121.514 89.128  78.714  1.00 38.58  ? 285 LEU B CG  1 
ATOM 3938 C CD1 . LEU B 2 295 ? 120.303 89.642  77.964  1.00 29.73  ? 285 LEU B CD1 1 
ATOM 3939 C CD2 . LEU B 2 295 ? 121.832 87.701  78.309  1.00 32.95  ? 285 LEU B CD2 1 
ATOM 3940 N N   . LEU B 2 296 ? 121.019 92.277  80.578  1.00 24.01  ? 286 LEU B N   1 
ATOM 3941 C CA  . LEU B 2 296 ? 120.436 92.455  81.900  1.00 32.17  ? 286 LEU B CA  1 
ATOM 3942 C C   . LEU B 2 296 ? 119.253 91.514  82.057  1.00 29.95  ? 286 LEU B C   1 
ATOM 3943 O O   . LEU B 2 296 ? 118.364 91.483  81.202  1.00 50.96  ? 286 LEU B O   1 
ATOM 3944 C CB  . LEU B 2 296 ? 119.998 93.904  82.123  1.00 36.01  ? 286 LEU B CB  1 
ATOM 3945 C CG  . LEU B 2 296 ? 121.106 94.961  82.164  1.00 35.20  ? 286 LEU B CG  1 
ATOM 3946 C CD1 . LEU B 2 296 ? 121.475 95.449  80.772  1.00 34.93  ? 286 LEU B CD1 1 
ATOM 3947 C CD2 . LEU B 2 296 ? 120.713 96.119  83.059  1.00 39.53  ? 286 LEU B CD2 1 
ATOM 3948 N N   . ALA B 2 297 ? 119.242 90.753  83.146  1.00 36.12  ? 287 ALA B N   1 
ATOM 3949 C CA  . ALA B 2 297 ? 118.211 89.755  83.385  1.00 31.34  ? 287 ALA B CA  1 
ATOM 3950 C C   . ALA B 2 297 ? 117.647 89.925  84.784  1.00 33.80  ? 287 ALA B C   1 
ATOM 3951 O O   . ALA B 2 297 ? 118.404 90.090  85.744  1.00 51.00  ? 287 ALA B O   1 
ATOM 3952 C CB  . ALA B 2 297 ? 118.768 88.339  83.212  1.00 29.28  ? 287 ALA B CB  1 
ATOM 3953 N N   . GLY B 2 298 ? 116.325 89.880  84.897  1.00 24.18  ? 288 GLY B N   1 
ATOM 3954 C CA  . GLY B 2 298 ? 115.678 89.902  86.191  1.00 30.58  ? 288 GLY B CA  1 
ATOM 3955 C C   . GLY B 2 298 ? 115.371 88.500  86.682  1.00 42.24  ? 288 GLY B C   1 
ATOM 3956 O O   . GLY B 2 298 ? 115.033 87.614  85.907  1.00 50.44  ? 288 GLY B O   1 
ATOM 3957 N N   . TYR B 2 299 ? 115.476 88.313  87.993  1.00 36.48  ? 289 TYR B N   1 
ATOM 3958 C CA  . TYR B 2 299 ? 115.421 86.989  88.589  1.00 39.07  ? 289 TYR B CA  1 
ATOM 3959 C C   . TYR B 2 299 ? 114.387 86.953  89.704  1.00 37.25  ? 289 TYR B C   1 
ATOM 3960 O O   . TYR B 2 299 ? 113.929 87.986  90.193  1.00 45.89  ? 289 TYR B O   1 
ATOM 3961 C CB  . TYR B 2 299 ? 116.785 86.562  89.133  1.00 28.45  ? 289 TYR B CB  1 
ATOM 3962 C CG  . TYR B 2 299 ? 117.836 86.331  88.076  1.00 28.40  ? 289 TYR B CG  1 
ATOM 3963 C CD1 . TYR B 2 299 ? 118.529 87.390  87.516  1.00 36.95  ? 289 TYR B CD1 1 
ATOM 3964 C CD2 . TYR B 2 299 ? 118.152 85.052  87.657  1.00 44.12  ? 289 TYR B CD2 1 
ATOM 3965 C CE1 . TYR B 2 299 ? 119.495 87.182  86.558  1.00 38.49  ? 289 TYR B CE1 1 
ATOM 3966 C CE2 . TYR B 2 299 ? 119.120 84.835  86.701  1.00 46.94  ? 289 TYR B CE2 1 
ATOM 3967 C CZ  . TYR B 2 299 ? 119.788 85.904  86.154  1.00 46.88  ? 289 TYR B CZ  1 
ATOM 3968 O OH  . TYR B 2 299 ? 120.754 85.691  85.199  1.00 46.77  ? 289 TYR B OH  1 
ATOM 3969 N N   . ASP B 2 300 ? 114.016 85.730  90.090  1.00 46.16  ? 290 ASP B N   1 
ATOM 3970 C CA  . ASP B 2 300 ? 113.103 85.529  91.208  1.00 39.47  ? 290 ASP B CA  1 
ATOM 3971 C C   . ASP B 2 300 ? 113.753 85.814  92.556  1.00 50.02  ? 290 ASP B C   1 
ATOM 3972 O O   . ASP B 2 300 ? 113.036 86.039  93.535  1.00 45.23  ? 290 ASP B O   1 
ATOM 3973 C CB  . ASP B 2 300 ? 112.563 84.099  91.201  1.00 39.02  ? 290 ASP B CB  1 
ATOM 3974 C CG  . ASP B 2 300 ? 111.815 83.764  89.931  1.00 50.95  ? 290 ASP B CG  1 
ATOM 3975 O OD1 . ASP B 2 300 ? 111.746 84.628  89.036  1.00 58.00  ? 290 ASP B OD1 1 
ATOM 3976 O OD2 . ASP B 2 300 ? 111.294 82.635  89.828  1.00 46.41  ? 290 ASP B OD2 1 
ATOM 3977 N N   . ASP B 2 301 ? 115.086 85.810  92.635  1.00 53.51  ? 291 ASP B N   1 
ATOM 3978 C CA  . ASP B 2 301 ? 115.777 86.008  93.903  1.00 48.81  ? 291 ASP B CA  1 
ATOM 3979 C C   . ASP B 2 301 ? 115.911 87.475  94.274  1.00 50.21  ? 291 ASP B C   1 
ATOM 3980 O O   . ASP B 2 301 ? 116.824 87.829  95.028  1.00 51.38  ? 291 ASP B O   1 
ATOM 3981 C CB  . ASP B 2 301 ? 117.157 85.346  93.877  1.00 48.14  ? 291 ASP B CB  1 
ATOM 3982 C CG  . ASP B 2 301 ? 118.095 85.970  92.862  1.00 57.35  ? 291 ASP B CG  1 
ATOM 3983 O OD1 . ASP B 2 301 ? 117.684 86.898  92.141  1.00 58.64  ? 291 ASP B OD1 1 
ATOM 3984 O OD2 . ASP B 2 301 ? 119.259 85.525  92.783  1.00 61.89  ? 291 ASP B OD2 1 
ATOM 3985 N N   . PHE B 2 302 ? 115.039 88.320  93.727  1.00 45.54  ? 292 PHE B N   1 
ATOM 3986 C CA  . PHE B 2 302 ? 114.870 89.739  94.035  1.00 42.99  ? 292 PHE B CA  1 
ATOM 3987 C C   . PHE B 2 302 ? 115.957 90.598  93.404  1.00 50.50  ? 292 PHE B C   1 
ATOM 3988 O O   . PHE B 2 302 ? 116.009 91.802  93.680  1.00 51.33  ? 292 PHE B O   1 
ATOM 3989 C CB  . PHE B 2 302 ? 114.841 90.030  95.542  1.00 48.80  ? 292 PHE B CB  1 
ATOM 3990 C CG  . PHE B 2 302 ? 113.781 89.274  96.308  1.00 52.44  ? 292 PHE B CG  1 
ATOM 3991 C CD1 . PHE B 2 302 ? 112.897 88.417  95.673  1.00 51.17  ? 292 PHE B CD1 1 
ATOM 3992 C CD2 . PHE B 2 302 ? 113.662 89.444  97.674  1.00 48.39  ? 292 PHE B CD2 1 
ATOM 3993 C CE1 . PHE B 2 302 ? 111.935 87.738  96.384  1.00 46.81  ? 292 PHE B CE1 1 
ATOM 3994 C CE2 . PHE B 2 302 ? 112.696 88.769  98.389  1.00 51.61  ? 292 PHE B CE2 1 
ATOM 3995 C CZ  . PHE B 2 302 ? 111.832 87.915  97.742  1.00 47.93  ? 292 PHE B CZ  1 
ATOM 3996 N N   . ASN B 2 303 ? 116.816 90.033  92.561  1.00 51.26  ? 293 ASN B N   1 
ATOM 3997 C CA  . ASN B 2 303 ? 117.964 90.745  92.024  1.00 40.73  ? 293 ASN B CA  1 
ATOM 3998 C C   . ASN B 2 303 ? 117.905 90.775  90.504  1.00 49.66  ? 293 ASN B C   1 
ATOM 3999 O O   . ASN B 2 303 ? 117.202 89.986  89.870  1.00 56.82  ? 293 ASN B O   1 
ATOM 4000 C CB  . ASN B 2 303 ? 119.284 90.101  92.466  1.00 43.12  ? 293 ASN B CB  1 
ATOM 4001 C CG  . ASN B 2 303 ? 119.487 90.154  93.962  1.00 54.60  ? 293 ASN B CG  1 
ATOM 4002 O OD1 . ASN B 2 303 ? 118.933 91.013  94.644  1.00 56.92  ? 293 ASN B OD1 1 
ATOM 4003 N ND2 . ASN B 2 303 ? 120.294 89.239  94.481  1.00 57.60  ? 293 ASN B ND2 1 
ATOM 4004 N N   . CYS B 2 304 ? 118.659 91.706  89.929  1.00 43.79  ? 294 CYS B N   1 
ATOM 4005 C CA  . CYS B 2 304 ? 118.879 91.786  88.491  1.00 35.13  ? 294 CYS B CA  1 
ATOM 4006 C C   . CYS B 2 304 ? 120.373 91.679  88.233  1.00 34.18  ? 294 CYS B C   1 
ATOM 4007 O O   . CYS B 2 304 ? 121.147 92.510  88.717  1.00 53.52  ? 294 CYS B O   1 
ATOM 4008 C CB  . CYS B 2 304 ? 118.321 93.089  87.919  1.00 39.19  ? 294 CYS B CB  1 
ATOM 4009 S SG  . CYS B 2 304 ? 118.734 93.367  86.187  1.00 65.95  ? 294 CYS B SG  1 
ATOM 4010 N N   . ASN B 2 305 ? 120.776 90.661  87.484  1.00 32.08  ? 295 ASN B N   1 
ATOM 4011 C CA  . ASN B 2 305 ? 122.182 90.421  87.186  1.00 43.58  ? 295 ASN B CA  1 
ATOM 4012 C C   . ASN B 2 305 ? 122.520 90.949  85.800  1.00 39.85  ? 295 ASN B C   1 
ATOM 4013 O O   . ASN B 2 305 ? 121.822 90.652  84.827  1.00 50.61  ? 295 ASN B O   1 
ATOM 4014 C CB  . ASN B 2 305 ? 122.522 88.933  87.279  1.00 44.66  ? 295 ASN B CB  1 
ATOM 4015 C CG  . ASN B 2 305 ? 122.252 88.361  88.653  1.00 47.24  ? 295 ASN B CG  1 
ATOM 4016 O OD1 . ASN B 2 305 ? 122.319 89.067  89.655  1.00 54.29  ? 295 ASN B OD1 1 
ATOM 4017 N ND2 . ASN B 2 305 ? 121.943 87.075  88.706  1.00 50.25  ? 295 ASN B ND2 1 
ATOM 4018 N N   . VAL B 2 306 ? 123.581 91.742  85.720  1.00 46.92  ? 296 VAL B N   1 
ATOM 4019 C CA  . VAL B 2 306 ? 124.087 92.250  84.452  1.00 36.93  ? 296 VAL B CA  1 
ATOM 4020 C C   . VAL B 2 306 ? 125.155 91.285  83.957  1.00 39.02  ? 296 VAL B C   1 
ATOM 4021 O O   . VAL B 2 306 ? 126.159 91.056  84.638  1.00 49.22  ? 296 VAL B O   1 
ATOM 4022 C CB  . VAL B 2 306 ? 124.652 93.668  84.607  1.00 40.81  ? 296 VAL B CB  1 
ATOM 4023 C CG1 . VAL B 2 306 ? 125.190 94.171  83.282  1.00 46.94  ? 296 VAL B CG1 1 
ATOM 4024 C CG2 . VAL B 2 306 ? 123.587 94.604  85.154  1.00 38.20  ? 296 VAL B CG2 1 
ATOM 4025 N N   . TRP B 2 307 ? 124.940 90.718  82.777  1.00 35.69  ? 297 TRP B N   1 
ATOM 4026 C CA  . TRP B 2 307 ? 125.848 89.736  82.209  1.00 31.07  ? 297 TRP B CA  1 
ATOM 4027 C C   . TRP B 2 307 ? 126.690 90.356  81.105  1.00 30.91  ? 297 TRP B C   1 
ATOM 4028 O O   . TRP B 2 307 ? 126.260 91.280  80.413  1.00 52.41  ? 297 TRP B O   1 
ATOM 4029 C CB  . TRP B 2 307 ? 125.081 88.535  81.648  1.00 33.40  ? 297 TRP B CB  1 
ATOM 4030 C CG  . TRP B 2 307 ? 124.418 87.691  82.689  1.00 42.67  ? 297 TRP B CG  1 
ATOM 4031 C CD1 . TRP B 2 307 ? 123.164 87.846  83.195  1.00 29.86  ? 297 TRP B CD1 1 
ATOM 4032 C CD2 . TRP B 2 307 ? 124.981 86.557  83.354  1.00 42.54  ? 297 TRP B CD2 1 
ATOM 4033 N NE1 . TRP B 2 307 ? 122.910 86.880  84.134  1.00 23.29  ? 297 TRP B NE1 1 
ATOM 4034 C CE2 . TRP B 2 307 ? 124.012 86.076  84.250  1.00 29.82  ? 297 TRP B CE2 1 
ATOM 4035 C CE3 . TRP B 2 307 ? 126.213 85.902  83.279  1.00 42.21  ? 297 TRP B CE3 1 
ATOM 4036 C CZ2 . TRP B 2 307 ? 124.234 84.974  85.063  1.00 36.68  ? 297 TRP B CZ2 1 
ATOM 4037 C CZ3 . TRP B 2 307 ? 126.431 84.808  84.085  1.00 32.55  ? 297 TRP B CZ3 1 
ATOM 4038 C CH2 . TRP B 2 307 ? 125.447 84.355  84.965  1.00 38.33  ? 297 TRP B CH2 1 
ATOM 4039 N N   . ASP B 2 308 ? 127.902 89.836  80.947  1.00 33.71  ? 298 ASP B N   1 
ATOM 4040 C CA  . ASP B 2 308 ? 128.703 90.121  79.765  1.00 33.92  ? 298 ASP B CA  1 
ATOM 4041 C C   . ASP B 2 308 ? 128.214 89.204  78.654  1.00 46.62  ? 298 ASP B C   1 
ATOM 4042 O O   . ASP B 2 308 ? 128.404 87.986  78.716  1.00 58.10  ? 298 ASP B O   1 
ATOM 4043 C CB  . ASP B 2 308 ? 130.182 89.901  80.063  1.00 47.27  ? 298 ASP B CB  1 
ATOM 4044 C CG  . ASP B 2 308 ? 131.085 90.421  78.967  1.00 50.59  ? 298 ASP B CG  1 
ATOM 4045 O OD1 . ASP B 2 308 ? 130.574 91.019  78.001  1.00 55.87  ? 298 ASP B OD1 1 
ATOM 4046 O OD2 . ASP B 2 308 ? 132.312 90.230  79.071  1.00 55.11  ? 298 ASP B OD2 1 
ATOM 4047 N N   . ALA B 2 309 ? 127.581 89.786  77.635  1.00 41.32  ? 299 ALA B N   1 
ATOM 4048 C CA  . ALA B 2 309 ? 126.972 88.978  76.585  1.00 41.09  ? 299 ALA B CA  1 
ATOM 4049 C C   . ALA B 2 309 ? 128.015 88.184  75.812  1.00 40.40  ? 299 ALA B C   1 
ATOM 4050 O O   . ALA B 2 309 ? 127.781 87.025  75.453  1.00 53.69  ? 299 ALA B O   1 
ATOM 4051 C CB  . ALA B 2 309 ? 126.166 89.868  75.642  1.00 45.00  ? 299 ALA B CB  1 
ATOM 4052 N N   . LEU B 2 310 ? 129.165 88.793  75.531  1.00 47.71  ? 300 LEU B N   1 
ATOM 4053 C CA  . LEU B 2 310 ? 130.175 88.129  74.715  1.00 57.47  ? 300 LEU B CA  1 
ATOM 4054 C C   . LEU B 2 310 ? 130.955 87.073  75.494  1.00 60.63  ? 300 LEU B C   1 
ATOM 4055 O O   . LEU B 2 310 ? 131.283 86.017  74.944  1.00 63.07  ? 300 LEU B O   1 
ATOM 4056 C CB  . LEU B 2 310 ? 131.125 89.166  74.122  1.00 59.22  ? 300 LEU B CB  1 
ATOM 4057 C CG  . LEU B 2 310 ? 130.451 90.237  73.266  1.00 59.57  ? 300 LEU B CG  1 
ATOM 4058 C CD1 . LEU B 2 310 ? 131.482 91.171  72.665  1.00 59.09  ? 300 LEU B CD1 1 
ATOM 4059 C CD2 . LEU B 2 310 ? 129.613 89.595  72.177  1.00 58.33  ? 300 LEU B CD2 1 
ATOM 4060 N N   . LYS B 2 311 ? 131.267 87.333  76.763  1.00 54.21  ? 301 LYS B N   1 
ATOM 4061 C CA  . LYS B 2 311 ? 132.158 86.472  77.531  1.00 53.41  ? 301 LYS B CA  1 
ATOM 4062 C C   . LYS B 2 311 ? 131.458 85.635  78.593  1.00 56.52  ? 301 LYS B C   1 
ATOM 4063 O O   . LYS B 2 311 ? 132.131 84.862  79.283  1.00 60.40  ? 301 LYS B O   1 
ATOM 4064 C CB  . LYS B 2 311 ? 133.257 87.310  78.189  1.00 57.66  ? 301 LYS B CB  1 
ATOM 4065 C CG  . LYS B 2 311 ? 134.189 87.986  77.207  1.00 56.08  ? 301 LYS B CG  1 
ATOM 4066 C CD  . LYS B 2 311 ? 135.309 88.701  77.930  1.00 56.52  ? 301 LYS B CD  1 
ATOM 4067 C CE  . LYS B 2 311 ? 136.106 87.740  78.789  1.00 56.26  ? 301 LYS B CE  1 
ATOM 4068 N NZ  . LYS B 2 311 ? 136.734 86.661  77.981  1.00 56.49  ? 301 LYS B NZ  1 
ATOM 4069 N N   . ALA B 2 312 ? 130.141 85.767  78.749  1.00 48.84  ? 302 ALA B N   1 
ATOM 4070 C CA  . ALA B 2 312 ? 129.369 84.976  79.711  1.00 49.43  ? 302 ALA B CA  1 
ATOM 4071 C C   . ALA B 2 312 ? 129.892 85.139  81.136  1.00 54.47  ? 302 ALA B C   1 
ATOM 4072 O O   . ALA B 2 312 ? 129.939 84.183  81.912  1.00 57.28  ? 302 ALA B O   1 
ATOM 4073 C CB  . ALA B 2 312 ? 129.341 83.499  79.319  1.00 48.45  ? 302 ALA B CB  1 
ATOM 4074 N N   . ASP B 2 313 ? 130.298 86.355  81.480  1.00 57.38  ? 303 ASP B N   1 
ATOM 4075 C CA  . ASP B 2 313 ? 130.735 86.698  82.825  1.00 55.50  ? 303 ASP B CA  1 
ATOM 4076 C C   . ASP B 2 313 ? 129.689 87.589  83.476  1.00 56.52  ? 303 ASP B C   1 
ATOM 4077 O O   . ASP B 2 313 ? 129.139 88.484  82.830  1.00 70.24  ? 303 ASP B O   1 
ATOM 4078 C CB  . ASP B 2 313 ? 132.088 87.411  82.808  1.00 58.16  ? 303 ASP B CB  1 
ATOM 4079 C CG  . ASP B 2 313 ? 133.214 86.510  82.358  1.00 61.02  ? 303 ASP B CG  1 
ATOM 4080 O OD1 . ASP B 2 313 ? 133.087 85.278  82.510  1.00 58.45  ? 303 ASP B OD1 1 
ATOM 4081 O OD2 . ASP B 2 313 ? 134.231 87.034  81.860  1.00 58.68  ? 303 ASP B OD2 1 
ATOM 4082 N N   . ARG B 2 314 ? 129.408 87.344  84.750  1.00 52.06  ? 304 ARG B N   1 
ATOM 4083 C CA  . ARG B 2 314 ? 128.484 88.206  85.481  1.00 51.85  ? 304 ARG B CA  1 
ATOM 4084 C C   . ARG B 2 314 ? 129.183 89.526  85.772  1.00 55.35  ? 304 ARG B C   1 
ATOM 4085 O O   . ARG B 2 314 ? 130.050 89.610  86.644  1.00 60.04  ? 304 ARG B O   1 
ATOM 4086 C CB  . ARG B 2 314 ? 128.015 87.539  86.767  1.00 49.56  ? 304 ARG B CB  1 
ATOM 4087 C CG  . ARG B 2 314 ? 126.992 88.363  87.520  1.00 55.76  ? 304 ARG B CG  1 
ATOM 4088 C CD  . ARG B 2 314 ? 126.894 87.951  88.974  1.00 58.60  ? 304 ARG B CD  1 
ATOM 4089 N NE  . ARG B 2 314 ? 126.399 86.591  89.132  1.00 64.74  ? 304 ARG B NE  1 
ATOM 4090 C CZ  . ARG B 2 314 ? 126.098 86.040  90.299  1.00 63.95  ? 304 ARG B CZ  1 
ATOM 4091 N NH1 . ARG B 2 314 ? 126.227 86.709  91.432  1.00 60.14  ? 304 ARG B NH1 1 
ATOM 4092 N NH2 . ARG B 2 314 ? 125.653 84.788  90.329  1.00 60.17  ? 304 ARG B NH2 1 
ATOM 4093 N N   . ALA B 2 315 ? 128.811 90.568  85.029  1.00 51.70  ? 305 ALA B N   1 
ATOM 4094 C CA  . ALA B 2 315 ? 129.488 91.852  85.147  1.00 41.54  ? 305 ALA B CA  1 
ATOM 4095 C C   . ALA B 2 315 ? 129.064 92.622  86.388  1.00 48.79  ? 305 ALA B C   1 
ATOM 4096 O O   . ALA B 2 315 ? 129.884 93.333  86.977  1.00 58.88  ? 305 ALA B O   1 
ATOM 4097 C CB  . ALA B 2 315 ? 129.224 92.697  83.903  1.00 44.94  ? 305 ALA B CB  1 
ATOM 4098 N N   . GLY B 2 316 ? 127.809 92.500  86.802  1.00 46.04  ? 306 GLY B N   1 
ATOM 4099 C CA  . GLY B 2 316 ? 127.353 93.233  87.966  1.00 41.05  ? 306 GLY B CA  1 
ATOM 4100 C C   . GLY B 2 316 ? 125.999 92.735  88.414  1.00 49.44  ? 306 GLY B C   1 
ATOM 4101 O O   . GLY B 2 316 ? 125.405 91.843  87.805  1.00 58.21  ? 306 GLY B O   1 
ATOM 4102 N N   . VAL B 2 317 ? 125.519 93.329  89.503  1.00 44.71  ? 307 VAL B N   1 
ATOM 4103 C CA  . VAL B 2 317 ? 124.246 92.963  90.113  1.00 37.57  ? 307 VAL B CA  1 
ATOM 4104 C C   . VAL B 2 317 ? 123.494 94.240  90.449  1.00 45.20  ? 307 VAL B C   1 
ATOM 4105 O O   . VAL B 2 317 ? 124.075 95.176  91.007  1.00 50.78  ? 307 VAL B O   1 
ATOM 4106 C CB  . VAL B 2 317 ? 124.438 92.111  91.384  1.00 37.18  ? 307 VAL B CB  1 
ATOM 4107 C CG1 . VAL B 2 317 ? 123.100 91.797  92.020  1.00 45.30  ? 307 VAL B CG1 1 
ATOM 4108 C CG2 . VAL B 2 317 ? 125.189 90.831  91.068  1.00 44.01  ? 307 VAL B CG2 1 
ATOM 4109 N N   . LEU B 2 318 ? 122.210 94.286  90.107  1.00 41.60  ? 308 LEU B N   1 
ATOM 4110 C CA  . LEU B 2 318 ? 121.314 95.342  90.568  1.00 26.18  ? 308 LEU B CA  1 
ATOM 4111 C C   . LEU B 2 318 ? 120.469 94.756  91.692  1.00 42.22  ? 308 LEU B C   1 
ATOM 4112 O O   . LEU B 2 318 ? 119.496 94.043  91.441  1.00 58.85  ? 308 LEU B O   1 
ATOM 4113 C CB  . LEU B 2 318 ? 120.439 95.861  89.432  1.00 38.31  ? 308 LEU B CB  1 
ATOM 4114 C CG  . LEU B 2 318 ? 121.096 96.213  88.100  1.00 40.96  ? 308 LEU B CG  1 
ATOM 4115 C CD1 . LEU B 2 318 ? 120.063 96.754  87.130  1.00 37.38  ? 308 LEU B CD1 1 
ATOM 4116 C CD2 . LEU B 2 318 ? 122.221 97.204  88.300  1.00 43.78  ? 308 LEU B CD2 1 
ATOM 4117 N N   . ALA B 2 319 ? 120.829 95.066  92.933  1.00 43.97  ? 309 ALA B N   1 
ATOM 4118 C CA  . ALA B 2 319 ? 120.128 94.549  94.108  1.00 43.43  ? 309 ALA B CA  1 
ATOM 4119 C C   . ALA B 2 319 ? 119.472 95.725  94.823  1.00 39.27  ? 309 ALA B C   1 
ATOM 4120 O O   . ALA B 2 319 ? 120.082 96.373  95.673  1.00 51.16  ? 309 ALA B O   1 
ATOM 4121 C CB  . ALA B 2 319 ? 121.080 93.796  95.026  1.00 43.61  ? 309 ALA B CB  1 
ATOM 4122 N N   . GLY B 2 320 ? 118.218 95.995  94.475  1.00 42.06  ? 310 GLY B N   1 
ATOM 4123 C CA  . GLY B 2 320 ? 117.497 97.087  95.094  1.00 43.78  ? 310 GLY B CA  1 
ATOM 4124 C C   . GLY B 2 320 ? 116.017 96.848  95.299  1.00 38.38  ? 310 GLY B C   1 
ATOM 4125 O O   . GLY B 2 320 ? 115.267 97.799  95.526  1.00 47.47  ? 310 GLY B O   1 
ATOM 4126 N N   . HIS B 2 321 ? 115.580 95.595  95.238  1.00 43.12  ? 311 HIS B N   1 
ATOM 4127 C CA  . HIS B 2 321 ? 114.167 95.268  95.354  1.00 42.32  ? 311 HIS B CA  1 
ATOM 4128 C C   . HIS B 2 321 ? 113.968 94.219  96.436  1.00 48.34  ? 311 HIS B C   1 
ATOM 4129 O O   . HIS B 2 321 ? 114.836 93.377  96.677  1.00 54.73  ? 311 HIS B O   1 
ATOM 4130 C CB  . HIS B 2 321 ? 113.591 94.747  94.030  1.00 41.56  ? 311 HIS B CB  1 
ATOM 4131 C CG  . HIS B 2 321 ? 113.418 95.802  92.982  1.00 46.95  ? 311 HIS B CG  1 
ATOM 4132 N ND1 . HIS B 2 321 ? 112.408 96.737  93.031  1.00 44.26  ? 311 HIS B ND1 1 
ATOM 4133 C CD2 . HIS B 2 321 ? 114.111 96.055  91.848  1.00 43.91  ? 311 HIS B CD2 1 
ATOM 4134 C CE1 . HIS B 2 321 ? 112.491 97.527  91.977  1.00 39.72  ? 311 HIS B CE1 1 
ATOM 4135 N NE2 . HIS B 2 321 ? 113.517 97.136  91.244  1.00 45.84  ? 311 HIS B NE2 1 
ATOM 4136 N N   . ASP B 2 322 ? 112.807 94.282  97.086  1.00 49.41  ? 312 ASP B N   1 
ATOM 4137 C CA  . ASP B 2 322 ? 112.470 93.383  98.179  1.00 44.57  ? 312 ASP B CA  1 
ATOM 4138 C C   . ASP B 2 322 ? 111.547 92.255  97.746  1.00 49.46  ? 312 ASP B C   1 
ATOM 4139 O O   . ASP B 2 322 ? 111.081 91.491  98.594  1.00 55.53  ? 312 ASP B O   1 
ATOM 4140 C CB  . ASP B 2 322 ? 111.830 94.161  99.328  1.00 47.28  ? 312 ASP B CB  1 
ATOM 4141 C CG  . ASP B 2 322 ? 112.737 95.239  99.879  1.00 62.29  ? 312 ASP B CG  1 
ATOM 4142 O OD1 . ASP B 2 322 ? 113.970 95.122  99.719  1.00 55.87  ? 312 ASP B OD1 1 
ATOM 4143 O OD2 . ASP B 2 322 ? 112.216 96.203  100.477 1.00 65.06  ? 312 ASP B OD2 1 
ATOM 4144 N N   . ASN B 2 323 ? 111.267 92.138  96.453  1.00 42.53  ? 313 ASN B N   1 
ATOM 4145 C CA  . ASN B 2 323 ? 110.490 91.026  95.934  1.00 29.45  ? 313 ASN B CA  1 
ATOM 4146 C C   . ASN B 2 323 ? 111.010 90.707  94.538  1.00 37.71  ? 313 ASN B C   1 
ATOM 4147 O O   . ASN B 2 323 ? 112.014 91.266  94.090  1.00 40.34  ? 313 ASN B O   1 
ATOM 4148 C CB  . ASN B 2 323 ? 108.992 91.347  95.960  1.00 33.37  ? 313 ASN B CB  1 
ATOM 4149 C CG  . ASN B 2 323 ? 108.137 90.104  96.058  1.00 40.48  ? 313 ASN B CG  1 
ATOM 4150 O OD1 . ASN B 2 323 ? 108.496 89.053  95.537  1.00 42.91  ? 313 ASN B OD1 1 
ATOM 4151 N ND2 . ASN B 2 323 ? 107.001 90.215  96.733  1.00 42.54  ? 313 ASN B ND2 1 
ATOM 4152 N N   . ARG B 2 324 ? 110.320 89.806  93.847  1.00 48.17  ? 314 ARG B N   1 
ATOM 4153 C CA  . ARG B 2 324 ? 110.791 89.322  92.556  1.00 45.41  ? 314 ARG B CA  1 
ATOM 4154 C C   . ARG B 2 324 ? 110.820 90.439  91.522  1.00 44.18  ? 314 ARG B C   1 
ATOM 4155 O O   . ARG B 2 324 ? 109.824 91.137  91.317  1.00 55.86  ? 314 ARG B O   1 
ATOM 4156 C CB  . ARG B 2 324 ? 109.894 88.182  92.076  1.00 36.28  ? 314 ARG B CB  1 
ATOM 4157 C CG  . ARG B 2 324 ? 110.164 87.740  90.659  1.00 37.30  ? 314 ARG B CG  1 
ATOM 4158 C CD  . ARG B 2 324 ? 109.141 86.724  90.196  1.00 42.78  ? 314 ARG B CD  1 
ATOM 4159 N NE  . ARG B 2 324 ? 109.182 85.507  90.995  1.00 47.24  ? 314 ARG B NE  1 
ATOM 4160 C CZ  . ARG B 2 324 ? 108.483 84.414  90.725  1.00 46.98  ? 314 ARG B CZ  1 
ATOM 4161 N NH1 . ARG B 2 324 ? 107.682 84.348  89.676  1.00 38.43  ? 314 ARG B NH1 1 
ATOM 4162 N NH2 . ARG B 2 324 ? 108.592 83.360  91.528  1.00 45.83  ? 314 ARG B NH2 1 
ATOM 4163 N N   . VAL B 2 325 ? 111.970 90.612  90.874  1.00 37.67  ? 315 VAL B N   1 
ATOM 4164 C CA  . VAL B 2 325 ? 112.071 91.532  89.746  1.00 41.57  ? 315 VAL B CA  1 
ATOM 4165 C C   . VAL B 2 325 ? 111.262 90.944  88.594  1.00 46.15  ? 315 VAL B C   1 
ATOM 4166 O O   . VAL B 2 325 ? 111.687 89.980  87.954  1.00 40.03  ? 315 VAL B O   1 
ATOM 4167 C CB  . VAL B 2 325 ? 113.528 91.772  89.337  1.00 40.90  ? 315 VAL B CB  1 
ATOM 4168 C CG1 . VAL B 2 325 ? 113.593 92.663  88.112  1.00 37.93  ? 315 VAL B CG1 1 
ATOM 4169 C CG2 . VAL B 2 325 ? 114.301 92.393  90.479  1.00 46.11  ? 315 VAL B CG2 1 
ATOM 4170 N N   . SER B 2 326 ? 110.100 91.531  88.321  1.00 40.43  ? 316 SER B N   1 
ATOM 4171 C CA  . SER B 2 326 ? 109.178 90.976  87.342  1.00 31.22  ? 316 SER B CA  1 
ATOM 4172 C C   . SER B 2 326 ? 109.424 91.483  85.931  1.00 36.93  ? 316 SER B C   1 
ATOM 4173 O O   . SER B 2 326 ? 109.006 90.829  84.971  1.00 42.50  ? 316 SER B O   1 
ATOM 4174 C CB  . SER B 2 326 ? 107.737 91.286  87.744  1.00 39.98  ? 316 SER B CB  1 
ATOM 4175 O OG  . SER B 2 326 ? 107.532 92.679  87.865  1.00 39.51  ? 316 SER B OG  1 
ATOM 4176 N N   . CYS B 2 327 ? 110.084 92.626  85.780  1.00 38.19  ? 317 CYS B N   1 
ATOM 4177 C CA  . CYS B 2 327 ? 110.262 93.225  84.468  1.00 32.40  ? 317 CYS B CA  1 
ATOM 4178 C C   . CYS B 2 327 ? 111.445 94.175  84.511  1.00 31.17  ? 317 CYS B C   1 
ATOM 4179 O O   . CYS B 2 327 ? 111.819 94.685  85.569  1.00 44.48  ? 317 CYS B O   1 
ATOM 4180 C CB  . CYS B 2 327 ? 108.998 93.964  84.023  1.00 33.49  ? 317 CYS B CB  1 
ATOM 4181 S SG  . CYS B 2 327 ? 108.379 95.156  85.224  1.00 41.22  ? 317 CYS B SG  1 
ATOM 4182 N N   . LEU B 2 328 ? 112.036 94.398  83.342  1.00 27.37  ? 318 LEU B N   1 
ATOM 4183 C CA  . LEU B 2 328 ? 113.069 95.410  83.198  1.00 24.09  ? 318 LEU B CA  1 
ATOM 4184 C C   . LEU B 2 328 ? 113.136 95.832  81.740  1.00 29.98  ? 318 LEU B C   1 
ATOM 4185 O O   . LEU B 2 328 ? 112.640 95.137  80.851  1.00 39.63  ? 318 LEU B O   1 
ATOM 4186 C CB  . LEU B 2 328 ? 114.430 94.917  83.699  1.00 34.49  ? 318 LEU B CB  1 
ATOM 4187 C CG  . LEU B 2 328 ? 115.121 93.715  83.066  1.00 19.08  ? 318 LEU B CG  1 
ATOM 4188 C CD1 . LEU B 2 328 ? 116.081 94.155  81.996  1.00 28.40  ? 318 LEU B CD1 1 
ATOM 4189 C CD2 . LEU B 2 328 ? 115.849 92.965  84.136  1.00 26.83  ? 318 LEU B CD2 1 
ATOM 4190 N N   . GLY B 2 329 ? 113.755 96.984  81.508  1.00 20.99  ? 319 GLY B N   1 
ATOM 4191 C CA  . GLY B 2 329 ? 113.906 97.494  80.161  1.00 23.75  ? 319 GLY B CA  1 
ATOM 4192 C C   . GLY B 2 329 ? 114.982 98.549  80.098  1.00 28.23  ? 319 GLY B C   1 
ATOM 4193 O O   . GLY B 2 329 ? 115.211 99.282  81.063  1.00 41.13  ? 319 GLY B O   1 
ATOM 4194 N N   . VAL B 2 330 ? 115.646 98.626  78.951  1.00 30.25  ? 320 VAL B N   1 
ATOM 4195 C CA  . VAL B 2 330 ? 116.726 99.574  78.713  1.00 30.57  ? 320 VAL B CA  1 
ATOM 4196 C C   . VAL B 2 330 ? 116.228 100.608 77.715  1.00 45.14  ? 320 VAL B C   1 
ATOM 4197 O O   . VAL B 2 330 ? 115.553 100.264 76.738  1.00 45.29  ? 320 VAL B O   1 
ATOM 4198 C CB  . VAL B 2 330 ? 117.998 98.873  78.197  1.00 31.00  ? 320 VAL B CB  1 
ATOM 4199 C CG1 . VAL B 2 330 ? 119.135 99.866  78.060  1.00 36.78  ? 320 VAL B CG1 1 
ATOM 4200 C CG2 . VAL B 2 330 ? 118.393 97.746  79.127  1.00 29.40  ? 320 VAL B CG2 1 
ATOM 4201 N N   . THR B 2 331 ? 116.562 101.873 77.959  1.00 45.88  ? 321 THR B N   1 
ATOM 4202 C CA  . THR B 2 331 ? 116.094 102.951 77.102  1.00 40.40  ? 321 THR B CA  1 
ATOM 4203 C C   . THR B 2 331 ? 116.643 102.801 75.687  1.00 45.88  ? 321 THR B C   1 
ATOM 4204 O O   . THR B 2 331 ? 117.638 102.114 75.441  1.00 47.33  ? 321 THR B O   1 
ATOM 4205 C CB  . THR B 2 331 ? 116.510 104.309 77.665  1.00 32.89  ? 321 THR B CB  1 
ATOM 4206 O OG1 . THR B 2 331 ? 117.927 104.329 77.866  1.00 46.07  ? 321 THR B OG1 1 
ATOM 4207 C CG2 . THR B 2 331 ? 115.820 104.592 78.974  1.00 33.09  ? 321 THR B CG2 1 
ATOM 4208 N N   . ASP B 2 332 ? 115.967 103.459 74.744  1.00 45.72  ? 322 ASP B N   1 
ATOM 4209 C CA  . ASP B 2 332 ? 116.390 103.400 73.350  1.00 51.41  ? 322 ASP B CA  1 
ATOM 4210 C C   . ASP B 2 332 ? 117.747 104.063 73.151  1.00 55.73  ? 322 ASP B C   1 
ATOM 4211 O O   . ASP B 2 332 ? 118.549 103.610 72.327  1.00 58.75  ? 322 ASP B O   1 
ATOM 4212 C CB  . ASP B 2 332 ? 115.332 104.041 72.458  1.00 51.18  ? 322 ASP B CB  1 
ATOM 4213 C CG  . ASP B 2 332 ? 113.999 103.335 72.550  1.00 61.55  ? 322 ASP B CG  1 
ATOM 4214 O OD1 . ASP B 2 332 ? 113.360 103.409 73.622  1.00 62.60  ? 322 ASP B OD1 1 
ATOM 4215 O OD2 . ASP B 2 332 ? 113.591 102.699 71.556  1.00 60.47  ? 322 ASP B OD2 1 
ATOM 4216 N N   . ASP B 2 333 ? 118.022 105.138 73.885  1.00 46.21  ? 323 ASP B N   1 
ATOM 4217 C CA  . ASP B 2 333 ? 119.334 105.767 73.828  1.00 46.27  ? 323 ASP B CA  1 
ATOM 4218 C C   . ASP B 2 333 ? 120.355 105.079 74.724  1.00 55.38  ? 323 ASP B C   1 
ATOM 4219 O O   . ASP B 2 333 ? 121.525 105.471 74.717  1.00 54.27  ? 323 ASP B O   1 
ATOM 4220 C CB  . ASP B 2 333 ? 119.234 107.252 74.192  1.00 51.02  ? 323 ASP B CB  1 
ATOM 4221 C CG  . ASP B 2 333 ? 118.598 107.481 75.544  1.00 57.01  ? 323 ASP B CG  1 
ATOM 4222 O OD1 . ASP B 2 333 ? 118.205 106.496 76.193  1.00 57.79  ? 323 ASP B OD1 1 
ATOM 4223 O OD2 . ASP B 2 333 ? 118.486 108.652 75.959  1.00 57.05  ? 323 ASP B OD2 1 
ATOM 4224 N N   . GLY B 2 334 ? 119.939 104.082 75.501  1.00 47.19  ? 324 GLY B N   1 
ATOM 4225 C CA  . GLY B 2 334 ? 120.850 103.349 76.351  1.00 42.85  ? 324 GLY B CA  1 
ATOM 4226 C C   . GLY B 2 334 ? 121.254 104.061 77.616  1.00 43.97  ? 324 GLY B C   1 
ATOM 4227 O O   . GLY B 2 334 ? 122.191 103.616 78.286  1.00 56.16  ? 324 GLY B O   1 
ATOM 4228 N N   . MET B 2 335 ? 120.572 105.147 77.972  1.00 48.57  ? 325 MET B N   1 
ATOM 4229 C CA  . MET B 2 335 ? 121.031 105.983 79.073  1.00 46.14  ? 325 MET B CA  1 
ATOM 4230 C C   . MET B 2 335 ? 120.757 105.332 80.420  1.00 52.15  ? 325 MET B C   1 
ATOM 4231 O O   . MET B 2 335 ? 121.560 105.463 81.349  1.00 66.73  ? 325 MET B O   1 
ATOM 4232 C CB  . MET B 2 335 ? 120.361 107.353 78.995  1.00 52.11  ? 325 MET B CB  1 
ATOM 4233 C CG  . MET B 2 335 ? 121.017 108.414 79.849  1.00 59.55  ? 325 MET B CG  1 
ATOM 4234 S SD  . MET B 2 335 ? 122.674 108.830 79.281  1.00 78.50  ? 325 MET B SD  1 
ATOM 4235 C CE  . MET B 2 335 ? 122.334 109.324 77.596  1.00 51.46  ? 325 MET B CE  1 
ATOM 4236 N N   . ALA B 2 336 ? 119.632 104.636 80.549  1.00 39.54  ? 326 ALA B N   1 
ATOM 4237 C CA  . ALA B 2 336 ? 119.226 104.089 81.831  1.00 36.63  ? 326 ALA B CA  1 
ATOM 4238 C C   . ALA B 2 336 ? 118.485 102.781 81.611  1.00 37.13  ? 326 ALA B C   1 
ATOM 4239 O O   . ALA B 2 336 ? 118.032 102.477 80.506  1.00 43.01  ? 326 ALA B O   1 
ATOM 4240 C CB  . ALA B 2 336 ? 118.346 105.072 82.607  1.00 34.38  ? 326 ALA B CB  1 
ATOM 4241 N N   . VAL B 2 337 ? 118.369 102.008 82.686  1.00 35.88  ? 327 VAL B N   1 
ATOM 4242 C CA  . VAL B 2 337 ? 117.595 100.776 82.701  1.00 29.78  ? 327 VAL B CA  1 
ATOM 4243 C C   . VAL B 2 337 ? 116.627 100.857 83.871  1.00 22.64  ? 327 VAL B C   1 
ATOM 4244 O O   . VAL B 2 337 ? 117.015 101.248 84.976  1.00 39.36  ? 327 VAL B O   1 
ATOM 4245 C CB  . VAL B 2 337 ? 118.498 99.529  82.807  1.00 34.53  ? 327 VAL B CB  1 
ATOM 4246 C CG1 . VAL B 2 337 ? 119.525 99.694  83.908  1.00 31.43  ? 327 VAL B CG1 1 
ATOM 4247 C CG2 . VAL B 2 337 ? 117.670 98.280  83.041  1.00 28.19  ? 327 VAL B CG2 1 
ATOM 4248 N N   . ALA B 2 338 ? 115.369 100.510 83.626  1.00 25.62  ? 328 ALA B N   1 
ATOM 4249 C CA  . ALA B 2 338 ? 114.352 100.465 84.662  1.00 23.62  ? 328 ALA B CA  1 
ATOM 4250 C C   . ALA B 2 338 ? 114.040 99.020  85.008  1.00 29.66  ? 328 ALA B C   1 
ATOM 4251 O O   . ALA B 2 338 ? 113.991 98.163  84.126  1.00 45.20  ? 328 ALA B O   1 
ATOM 4252 C CB  . ALA B 2 338 ? 113.074 101.178 84.224  1.00 27.77  ? 328 ALA B CB  1 
ATOM 4253 N N   . THR B 2 339 ? 113.851 98.751  86.297  1.00 39.16  ? 329 THR B N   1 
ATOM 4254 C CA  . THR B 2 339 ? 113.448 97.438  86.783  1.00 33.97  ? 329 THR B CA  1 
ATOM 4255 C C   . THR B 2 339 ? 112.178 97.589  87.601  1.00 34.81  ? 329 THR B C   1 
ATOM 4256 O O   . THR B 2 339 ? 112.112 98.426  88.505  1.00 45.77  ? 329 THR B O   1 
ATOM 4257 C CB  . THR B 2 339 ? 114.534 96.781  87.637  1.00 31.45  ? 329 THR B CB  1 
ATOM 4258 O OG1 . THR B 2 339 ? 114.651 97.475  88.883  1.00 46.36  ? 329 THR B OG1 1 
ATOM 4259 C CG2 . THR B 2 339 ? 115.869 96.813  86.921  1.00 35.96  ? 329 THR B CG2 1 
ATOM 4260 N N   . GLY B 2 340 ? 111.175 96.787  87.276  1.00 35.50  ? 330 GLY B N   1 
ATOM 4261 C CA  . GLY B 2 340 ? 109.961 96.724  88.058  1.00 35.30  ? 330 GLY B CA  1 
ATOM 4262 C C   . GLY B 2 340 ? 109.926 95.456  88.879  1.00 42.06  ? 330 GLY B C   1 
ATOM 4263 O O   . GLY B 2 340 ? 110.588 94.475  88.535  1.00 48.19  ? 330 GLY B O   1 
ATOM 4264 N N   . SER B 2 341 ? 109.181 95.460  89.979  1.00 35.90  ? 331 SER B N   1 
ATOM 4265 C CA  . SER B 2 341 ? 109.245 94.348  90.911  1.00 40.01  ? 331 SER B CA  1 
ATOM 4266 C C   . SER B 2 341 ? 107.899 94.160  91.584  1.00 38.68  ? 331 SER B C   1 
ATOM 4267 O O   . SER B 2 341 ? 107.046 95.049  91.583  1.00 44.70  ? 331 SER B O   1 
ATOM 4268 C CB  . SER B 2 341 ? 110.335 94.555  91.962  1.00 45.68  ? 331 SER B CB  1 
ATOM 4269 O OG  . SER B 2 341 ? 110.331 93.504  92.906  1.00 47.42  ? 331 SER B OG  1 
ATOM 4270 N N   . TRP B 2 342 ? 107.725 92.971  92.158  1.00 39.79  ? 332 TRP B N   1 
ATOM 4271 C CA  . TRP B 2 342 ? 106.538 92.641  92.931  1.00 40.83  ? 332 TRP B CA  1 
ATOM 4272 C C   . TRP B 2 342 ? 106.429 93.436  94.225  1.00 45.72  ? 332 TRP B C   1 
ATOM 4273 O O   . TRP B 2 342 ? 105.380 93.381  94.873  1.00 47.94  ? 332 TRP B O   1 
ATOM 4274 C CB  . TRP B 2 342 ? 106.524 91.146  93.236  1.00 39.75  ? 332 TRP B CB  1 
ATOM 4275 C CG  . TRP B 2 342 ? 106.260 90.291  92.040  1.00 41.31  ? 332 TRP B CG  1 
ATOM 4276 C CD1 . TRP B 2 342 ? 106.130 90.704  90.750  1.00 46.61  ? 332 TRP B CD1 1 
ATOM 4277 C CD2 . TRP B 2 342 ? 106.082 88.873  92.027  1.00 48.55  ? 332 TRP B CD2 1 
ATOM 4278 N NE1 . TRP B 2 342 ? 105.886 89.631  89.931  1.00 44.68  ? 332 TRP B NE1 1 
ATOM 4279 C CE2 . TRP B 2 342 ? 105.851 88.494  90.692  1.00 50.49  ? 332 TRP B CE2 1 
ATOM 4280 C CE3 . TRP B 2 342 ? 106.092 87.886  93.014  1.00 45.08  ? 332 TRP B CE3 1 
ATOM 4281 C CZ2 . TRP B 2 342 ? 105.634 87.173  90.321  1.00 47.36  ? 332 TRP B CZ2 1 
ATOM 4282 C CZ3 . TRP B 2 342 ? 105.879 86.579  92.644  1.00 42.73  ? 332 TRP B CZ3 1 
ATOM 4283 C CH2 . TRP B 2 342 ? 105.652 86.232  91.310  1.00 42.86  ? 332 TRP B CH2 1 
ATOM 4284 N N   . ASP B 2 343 ? 107.475 94.156  94.625  1.00 38.84  ? 333 ASP B N   1 
ATOM 4285 C CA  . ASP B 2 343 ? 107.402 95.011  95.801  1.00 38.54  ? 333 ASP B CA  1 
ATOM 4286 C C   . ASP B 2 343 ? 106.730 96.346  95.510  1.00 41.46  ? 333 ASP B C   1 
ATOM 4287 O O   . ASP B 2 343 ? 106.720 97.215  96.388  1.00 47.02  ? 333 ASP B O   1 
ATOM 4288 C CB  . ASP B 2 343 ? 108.799 95.241  96.386  1.00 39.02  ? 333 ASP B CB  1 
ATOM 4289 C CG  . ASP B 2 343 ? 109.723 95.978  95.439  1.00 52.00  ? 333 ASP B CG  1 
ATOM 4290 O OD1 . ASP B 2 343 ? 109.313 96.273  94.302  1.00 55.89  ? 333 ASP B OD1 1 
ATOM 4291 O OD2 . ASP B 2 343 ? 110.871 96.270  95.838  1.00 51.49  ? 333 ASP B OD2 1 
ATOM 4292 N N   . SER B 2 344 ? 106.199 96.522  94.296  1.00 35.50  ? 334 SER B N   1 
ATOM 4293 C CA  . SER B 2 344 ? 105.391 97.662  93.866  1.00 34.11  ? 334 SER B CA  1 
ATOM 4294 C C   . SER B 2 344 ? 106.209 98.908  93.560  1.00 37.84  ? 334 SER B C   1 
ATOM 4295 O O   . SER B 2 344 ? 105.655 100.008 93.523  1.00 46.22  ? 334 SER B O   1 
ATOM 4296 C CB  . SER B 2 344 ? 104.299 98.010  94.884  1.00 36.28  ? 334 SER B CB  1 
ATOM 4297 O OG  . SER B 2 344 ? 104.851 98.556  96.066  1.00 46.20  ? 334 SER B OG  1 
ATOM 4298 N N   . PHE B 2 345 ? 107.514 98.783  93.345  1.00 38.42  ? 335 PHE B N   1 
ATOM 4299 C CA  . PHE B 2 345 ? 108.350 99.928  93.024  1.00 32.30  ? 335 PHE B CA  1 
ATOM 4300 C C   . PHE B 2 345 ? 109.047 99.723  91.688  1.00 33.56  ? 335 PHE B C   1 
ATOM 4301 O O   . PHE B 2 345 ? 109.354 98.595  91.294  1.00 49.04  ? 335 PHE B O   1 
ATOM 4302 C CB  . PHE B 2 345 ? 109.394 100.183 94.117  1.00 39.41  ? 335 PHE B CB  1 
ATOM 4303 C CG  . PHE B 2 345 ? 108.798 100.516 95.448  1.00 40.43  ? 335 PHE B CG  1 
ATOM 4304 C CD1 . PHE B 2 345 ? 108.292 101.775 95.696  1.00 41.49  ? 335 PHE B CD1 1 
ATOM 4305 C CD2 . PHE B 2 345 ? 108.735 99.567  96.448  1.00 42.27  ? 335 PHE B CD2 1 
ATOM 4306 C CE1 . PHE B 2 345 ? 107.737 102.079 96.914  1.00 42.85  ? 335 PHE B CE1 1 
ATOM 4307 C CE2 . PHE B 2 345 ? 108.179 99.867  97.666  1.00 43.79  ? 335 PHE B CE2 1 
ATOM 4308 C CZ  . PHE B 2 345 ? 107.682 101.124 97.901  1.00 44.83  ? 335 PHE B CZ  1 
ATOM 4309 N N   . LEU B 2 346 ? 109.291 100.831 90.998  1.00 25.95  ? 336 LEU B N   1 
ATOM 4310 C CA  . LEU B 2 346 ? 110.137 100.866 89.816  1.00 34.60  ? 336 LEU B CA  1 
ATOM 4311 C C   . LEU B 2 346 ? 111.364 101.704 90.127  1.00 35.63  ? 336 LEU B C   1 
ATOM 4312 O O   . LEU B 2 346 ? 111.267 102.733 90.800  1.00 38.07  ? 336 LEU B O   1 
ATOM 4313 C CB  . LEU B 2 346 ? 109.408 101.457 88.610  1.00 38.32  ? 336 LEU B CB  1 
ATOM 4314 C CG  . LEU B 2 346 ? 108.192 100.720 88.066  1.00 40.47  ? 336 LEU B CG  1 
ATOM 4315 C CD1 . LEU B 2 346 ? 106.999 101.649 88.076  1.00 41.80  ? 336 LEU B CD1 1 
ATOM 4316 C CD2 . LEU B 2 346 ? 108.474 100.213 86.667  1.00 35.17  ? 336 LEU B CD2 1 
ATOM 4317 N N   . LYS B 2 347 ? 112.516 101.263 89.644  1.00 25.50  ? 337 LYS B N   1 
ATOM 4318 C CA  . LYS B 2 347 ? 113.765 101.956 89.902  1.00 29.85  ? 337 LYS B CA  1 
ATOM 4319 C C   . LYS B 2 347 ? 114.501 102.192 88.595  1.00 29.60  ? 337 LYS B C   1 
ATOM 4320 O O   . LYS B 2 347 ? 114.490 101.340 87.705  1.00 42.24  ? 337 LYS B O   1 
ATOM 4321 C CB  . LYS B 2 347 ? 114.626 101.159 90.878  1.00 29.75  ? 337 LYS B CB  1 
ATOM 4322 C CG  . LYS B 2 347 ? 113.956 100.993 92.225  1.00 34.27  ? 337 LYS B CG  1 
ATOM 4323 C CD  . LYS B 2 347 ? 114.911 100.533 93.293  1.00 32.05  ? 337 LYS B CD  1 
ATOM 4324 C CE  . LYS B 2 347 ? 114.261 100.647 94.655  1.00 31.03  ? 337 LYS B CE  1 
ATOM 4325 N NZ  . LYS B 2 347 ? 115.179 100.216 95.738  1.00 43.13  ? 337 LYS B NZ  1 
ATOM 4326 N N   . ILE B 2 348 ? 115.140 103.353 88.488  1.00 24.33  ? 338 ILE B N   1 
ATOM 4327 C CA  . ILE B 2 348 ? 115.906 103.741 87.311  1.00 21.02  ? 338 ILE B CA  1 
ATOM 4328 C C   . ILE B 2 348 ? 117.378 103.680 87.681  1.00 29.51  ? 338 ILE B C   1 
ATOM 4329 O O   . ILE B 2 348 ? 117.790 104.241 88.702  1.00 46.87  ? 338 ILE B O   1 
ATOM 4330 C CB  . ILE B 2 348 ? 115.523 105.149 86.825  1.00 28.50  ? 338 ILE B CB  1 
ATOM 4331 C CG1 . ILE B 2 348 ? 114.004 105.311 86.746  1.00 32.50  ? 338 ILE B CG1 1 
ATOM 4332 C CG2 . ILE B 2 348 ? 116.142 105.428 85.476  1.00 33.75  ? 338 ILE B CG2 1 
ATOM 4333 C CD1 . ILE B 2 348 ? 113.362 104.553 85.626  1.00 36.25  ? 338 ILE B CD1 1 
ATOM 4334 N N   . TRP B 2 349 ? 118.166 102.990 86.863  1.00 33.31  ? 339 TRP B N   1 
ATOM 4335 C CA  . TRP B 2 349 ? 119.568 102.733 87.147  1.00 19.93  ? 339 TRP B CA  1 
ATOM 4336 C C   . TRP B 2 349 ? 120.436 103.248 86.011  1.00 36.79  ? 339 TRP B C   1 
ATOM 4337 O O   . TRP B 2 349 ? 120.061 103.151 84.840  1.00 56.08  ? 339 TRP B O   1 
ATOM 4338 C CB  . TRP B 2 349 ? 119.841 101.236 87.328  1.00 22.85  ? 339 TRP B CB  1 
ATOM 4339 C CG  . TRP B 2 349 ? 118.895 100.515 88.230  1.00 37.19  ? 339 TRP B CG  1 
ATOM 4340 C CD1 . TRP B 2 349 ? 117.599 100.195 87.967  1.00 45.09  ? 339 TRP B CD1 1 
ATOM 4341 C CD2 . TRP B 2 349 ? 119.184 99.980  89.524  1.00 44.28  ? 339 TRP B CD2 1 
ATOM 4342 N NE1 . TRP B 2 349 ? 117.054 99.515  89.025  1.00 40.01  ? 339 TRP B NE1 1 
ATOM 4343 C CE2 . TRP B 2 349 ? 118.009 99.370  89.996  1.00 38.59  ? 339 TRP B CE2 1 
ATOM 4344 C CE3 . TRP B 2 349 ? 120.322 99.967  90.335  1.00 47.65  ? 339 TRP B CE3 1 
ATOM 4345 C CZ2 . TRP B 2 349 ? 117.937 98.753  91.239  1.00 37.44  ? 339 TRP B CZ2 1 
ATOM 4346 C CZ3 . TRP B 2 349 ? 120.247 99.358  91.569  1.00 41.25  ? 339 TRP B CZ3 1 
ATOM 4347 C CH2 . TRP B 2 349 ? 119.064 98.758  92.009  1.00 40.60  ? 339 TRP B CH2 1 
ATOM 4348 N N   . ASN B 2 350 ? 121.595 103.795 86.362  1.00 46.89  ? 340 ASN B N   1 
ATOM 4349 C CA  . ASN B 2 350 ? 122.679 103.995 85.409  1.00 46.50  ? 340 ASN B CA  1 
ATOM 4350 C C   . ASN B 2 350 ? 123.967 104.170 86.197  1.00 52.55  ? 340 ASN B C   1 
ATOM 4351 O O   . ASN B 2 350 ? 123.951 104.381 87.411  1.00 58.12  ? 340 ASN B O   1 
ATOM 4352 C CB  . ASN B 2 350 ? 122.424 105.182 84.473  1.00 45.75  ? 340 ASN B CB  1 
ATOM 4353 C CG  . ASN B 2 350 ? 122.121 106.459 85.211  1.00 55.70  ? 340 ASN B CG  1 
ATOM 4354 O OD1 . ASN B 2 350 ? 123.023 107.129 85.709  1.00 63.52  ? 340 ASN B OD1 1 
ATOM 4355 N ND2 . ASN B 2 350 ? 120.846 106.818 85.270  1.00 58.63  ? 340 ASN B ND2 1 
ATOM 4356 N N   . GLY B 2 351 ? 125.092 104.076 85.490  1.00 55.60  ? 341 GLY B N   1 
ATOM 4357 C CA  . GLY B 2 351 ? 126.390 104.164 86.122  1.00 58.11  ? 341 GLY B CA  1 
ATOM 4358 C C   . GLY B 2 351 ? 126.886 105.592 86.247  1.00 64.91  ? 341 GLY B C   1 
ATOM 4359 O O   . GLY B 2 351 ? 126.244 106.552 85.826  1.00 69.26  ? 341 GLY B O   1 
ATOM 4360 N N   . SER B 2 352 ? 128.068 105.722 86.844  1.00 77.45  ? 342 SER B N   1 
ATOM 4361 C CA  . SER B 2 352 ? 128.722 107.011 87.001  1.00 77.85  ? 342 SER B CA  1 
ATOM 4362 C C   . SER B 2 352 ? 130.194 106.877 86.647  1.00 79.12  ? 342 SER B C   1 
ATOM 4363 O O   . SER B 2 352 ? 130.802 105.821 86.843  1.00 76.52  ? 342 SER B O   1 
ATOM 4364 C CB  . SER B 2 352 ? 128.570 107.554 88.427  1.00 75.46  ? 342 SER B CB  1 
ATOM 4365 O OG  . SER B 2 352 ? 129.140 106.666 89.372  1.00 77.30  ? 342 SER B OG  1 
ATOM 4366 N N   . SER B 2 353 ? 130.759 107.957 86.118  1.00 91.31  ? 343 SER B N   1 
ATOM 4367 C CA  . SER B 2 353 ? 132.166 107.978 85.738  1.00 91.14  ? 343 SER B CA  1 
ATOM 4368 C C   . SER B 2 353 ? 133.067 107.886 86.963  1.00 90.08  ? 343 SER B C   1 
ATOM 4369 O O   . SER B 2 353 ? 133.761 106.888 87.161  1.00 90.66  ? 343 SER B O   1 
ATOM 4370 C CB  . SER B 2 353 ? 132.487 109.245 84.945  1.00 90.68  ? 343 SER B CB  1 
ATOM 4371 O OG  . SER B 2 353 ? 131.716 109.314 83.759  1.00 91.95  ? 343 SER B OG  1 
ATOM 4372 N N   . THR C 3 6   ? 90.677  61.411  62.532  1.00 147.05 ? 6   THR C N   1 
ATOM 4373 C CA  . THR C 3 6   ? 91.757  61.719  61.602  1.00 148.47 ? 6   THR C CA  1 
ATOM 4374 C C   . THR C 3 6   ? 92.441  63.031  61.972  1.00 148.38 ? 6   THR C C   1 
ATOM 4375 O O   . THR C 3 6   ? 93.033  63.696  61.123  1.00 147.70 ? 6   THR C O   1 
ATOM 4376 C CB  . THR C 3 6   ? 91.245  61.807  60.153  1.00 147.49 ? 6   THR C CB  1 
ATOM 4377 O OG1 . THR C 3 6   ? 90.248  62.833  60.057  1.00 147.27 ? 6   THR C OG1 1 
ATOM 4378 C CG2 . THR C 3 6   ? 90.643  60.479  59.719  1.00 145.51 ? 6   THR C CG2 1 
ATOM 4379 N N   . ALA C 3 7   ? 92.348  63.401  63.251  1.00 150.35 ? 7   ALA C N   1 
ATOM 4380 C CA  . ALA C 3 7   ? 93.001  64.621  63.714  1.00 150.41 ? 7   ALA C CA  1 
ATOM 4381 C C   . ALA C 3 7   ? 94.509  64.435  63.828  1.00 151.05 ? 7   ALA C C   1 
ATOM 4382 O O   . ALA C 3 7   ? 95.280  65.323  63.447  1.00 150.72 ? 7   ALA C O   1 
ATOM 4383 C CB  . ALA C 3 7   ? 92.411  65.056  65.055  1.00 148.72 ? 7   ALA C CB  1 
ATOM 4384 N N   . SER C 3 8   ? 94.948  63.289  64.355  1.00 150.84 ? 8   SER C N   1 
ATOM 4385 C CA  . SER C 3 8   ? 96.378  63.050  64.528  1.00 149.80 ? 8   SER C CA  1 
ATOM 4386 C C   . SER C 3 8   ? 97.100  62.966  63.189  1.00 150.13 ? 8   SER C C   1 
ATOM 4387 O O   . SER C 3 8   ? 98.203  63.506  63.039  1.00 151.39 ? 8   SER C O   1 
ATOM 4388 C CB  . SER C 3 8   ? 96.600  61.773  65.338  1.00 149.69 ? 8   SER C CB  1 
ATOM 4389 O OG  . SER C 3 8   ? 96.009  61.875  66.621  1.00 149.20 ? 8   SER C OG  1 
ATOM 4390 N N   . ILE C 3 9   ? 96.500  62.292  62.205  1.00 148.84 ? 9   ILE C N   1 
ATOM 4391 C CA  . ILE C 3 9   ? 97.154  62.144  60.908  1.00 149.40 ? 9   ILE C CA  1 
ATOM 4392 C C   . ILE C 3 9   ? 97.255  63.490  60.199  1.00 149.90 ? 9   ILE C C   1 
ATOM 4393 O O   . ILE C 3 9   ? 98.239  63.768  59.503  1.00 149.65 ? 9   ILE C O   1 
ATOM 4394 C CB  . ILE C 3 9   ? 96.418  61.092  60.053  1.00 148.95 ? 9   ILE C CB  1 
ATOM 4395 C CG1 . ILE C 3 9   ? 97.151  60.863  58.730  1.00 148.29 ? 9   ILE C CG1 1 
ATOM 4396 C CG2 . ILE C 3 9   ? 94.972  61.494  59.808  1.00 149.03 ? 9   ILE C CG2 1 
ATOM 4397 C CD1 . ILE C 3 9   ? 98.504  60.215  58.894  1.00 149.70 ? 9   ILE C CD1 1 
ATOM 4398 N N   . ALA C 3 10  ? 96.244  64.348  60.362  1.00 149.41 ? 10  ALA C N   1 
ATOM 4399 C CA  . ALA C 3 10  ? 96.305  65.682  59.772  1.00 149.03 ? 10  ALA C CA  1 
ATOM 4400 C C   . ALA C 3 10  ? 97.381  66.533  60.435  1.00 149.21 ? 10  ALA C C   1 
ATOM 4401 O O   . ALA C 3 10  ? 98.093  67.283  59.757  1.00 148.85 ? 10  ALA C O   1 
ATOM 4402 C CB  . ALA C 3 10  ? 94.941  66.364  59.873  1.00 148.31 ? 10  ALA C CB  1 
ATOM 4403 N N   . GLN C 3 11  ? 97.512  66.433  61.760  1.00 146.39 ? 11  GLN C N   1 
ATOM 4404 C CA  . GLN C 3 11  ? 98.547  67.182  62.464  1.00 145.63 ? 11  GLN C CA  1 
ATOM 4405 C C   . GLN C 3 11  ? 99.943  66.693  62.100  1.00 145.63 ? 11  GLN C C   1 
ATOM 4406 O O   . GLN C 3 11  ? 100.881 67.496  62.032  1.00 145.78 ? 11  GLN C O   1 
ATOM 4407 C CB  . GLN C 3 11  ? 98.327  67.088  63.974  1.00 145.21 ? 11  GLN C CB  1 
ATOM 4408 C CG  . GLN C 3 11  ? 99.330  67.878  64.799  1.00 145.44 ? 11  GLN C CG  1 
ATOM 4409 C CD  . GLN C 3 11  ? 99.104  67.727  66.290  1.00 146.87 ? 11  GLN C CD  1 
ATOM 4410 O OE1 . GLN C 3 11  ? 98.202  67.010  66.724  1.00 146.91 ? 11  GLN C OE1 1 
ATOM 4411 N NE2 . GLN C 3 11  ? 99.926  68.403  67.084  1.00 146.55 ? 11  GLN C NE2 1 
ATOM 4412 N N   . ALA C 3 12  ? 100.098 65.388  61.865  1.00 145.02 ? 12  ALA C N   1 
ATOM 4413 C CA  . ALA C 3 12  ? 101.410 64.844  61.530  1.00 144.97 ? 12  ALA C CA  1 
ATOM 4414 C C   . ALA C 3 12  ? 101.932 65.416  60.219  1.00 146.46 ? 12  ALA C C   1 
ATOM 4415 O O   . ALA C 3 12  ? 103.123 65.722  60.098  1.00 147.28 ? 12  ALA C O   1 
ATOM 4416 C CB  . ALA C 3 12  ? 101.343 63.319  61.462  1.00 145.02 ? 12  ALA C CB  1 
ATOM 4417 N N   . ARG C 3 13  ? 101.055 65.566  59.222  1.00 143.61 ? 13  ARG C N   1 
ATOM 4418 C CA  . ARG C 3 13  ? 101.482 66.128  57.944  1.00 142.92 ? 13  ARG C CA  1 
ATOM 4419 C C   . ARG C 3 13  ? 101.961 67.564  58.103  1.00 143.53 ? 13  ARG C C   1 
ATOM 4420 O O   . ARG C 3 13  ? 102.956 67.966  57.489  1.00 141.46 ? 13  ARG C O   1 
ATOM 4421 C CB  . ARG C 3 13  ? 100.338 66.059  56.933  1.00 142.34 ? 13  ARG C CB  1 
ATOM 4422 C CG  . ARG C 3 13  ? 99.846  64.653  56.639  1.00 143.73 ? 13  ARG C CG  1 
ATOM 4423 C CD  . ARG C 3 13  ? 98.705  64.666  55.636  1.00 144.07 ? 13  ARG C CD  1 
ATOM 4424 N NE  . ARG C 3 13  ? 98.245  63.320  55.316  1.00 144.72 ? 13  ARG C NE  1 
ATOM 4425 C CZ  . ARG C 3 13  ? 98.725  62.580  54.326  1.00 143.98 ? 13  ARG C CZ  1 
ATOM 4426 N NH1 . ARG C 3 13  ? 99.685  63.026  53.532  1.00 142.91 ? 13  ARG C NH1 1 
ATOM 4427 N NH2 . ARG C 3 13  ? 98.229  61.362  54.127  1.00 143.26 ? 13  ARG C NH2 1 
ATOM 4428 N N   . LYS C 3 14  ? 101.263 68.357  58.920  1.00 138.68 ? 14  LYS C N   1 
ATOM 4429 C CA  . LYS C 3 14  ? 101.657 69.748  59.114  1.00 137.73 ? 14  LYS C CA  1 
ATOM 4430 C C   . LYS C 3 14  ? 102.999 69.854  59.828  1.00 138.11 ? 14  LYS C C   1 
ATOM 4431 O O   . LYS C 3 14  ? 103.844 70.675  59.452  1.00 138.95 ? 14  LYS C O   1 
ATOM 4432 C CB  . LYS C 3 14  ? 100.574 70.495  59.890  1.00 137.00 ? 14  LYS C CB  1 
ATOM 4433 C CG  . LYS C 3 14  ? 100.829 71.985  60.032  1.00 138.59 ? 14  LYS C CG  1 
ATOM 4434 C CD  . LYS C 3 14  ? 99.673  72.675  60.736  1.00 138.80 ? 14  LYS C CD  1 
ATOM 4435 C CE  . LYS C 3 14  ? 99.901  74.173  60.837  1.00 137.21 ? 14  LYS C CE  1 
ATOM 4436 N NZ  . LYS C 3 14  ? 98.763  74.862  61.507  1.00 135.59 ? 14  LYS C NZ  1 
ATOM 4437 N N   . LEU C 3 15  ? 103.213 69.039  60.864  1.00 139.11 ? 15  LEU C N   1 
ATOM 4438 C CA  . LEU C 3 15  ? 104.478 69.087  61.592  1.00 139.00 ? 15  LEU C CA  1 
ATOM 4439 C C   . LEU C 3 15  ? 105.644 68.649  60.714  1.00 138.96 ? 15  LEU C C   1 
ATOM 4440 O O   . LEU C 3 15  ? 106.722 69.251  60.761  1.00 140.85 ? 15  LEU C O   1 
ATOM 4441 C CB  . LEU C 3 15  ? 104.397 68.219  62.847  1.00 139.57 ? 15  LEU C CB  1 
ATOM 4442 C CG  . LEU C 3 15  ? 105.658 68.176  63.712  1.00 139.25 ? 15  LEU C CG  1 
ATOM 4443 C CD1 . LEU C 3 15  ? 106.031 69.571  64.183  1.00 138.13 ? 15  LEU C CD1 1 
ATOM 4444 C CD2 . LEU C 3 15  ? 105.468 67.241  64.894  1.00 138.23 ? 15  LEU C CD2 1 
ATOM 4445 N N   . VAL C 3 16  ? 105.449 67.602  59.910  1.00 141.46 ? 16  VAL C N   1 
ATOM 4446 C CA  . VAL C 3 16  ? 106.496 67.164  58.990  1.00 142.64 ? 16  VAL C CA  1 
ATOM 4447 C C   . VAL C 3 16  ? 106.768 68.236  57.943  1.00 142.07 ? 16  VAL C C   1 
ATOM 4448 O O   . VAL C 3 16  ? 107.925 68.513  57.601  1.00 141.75 ? 16  VAL C O   1 
ATOM 4449 C CB  . VAL C 3 16  ? 106.116 65.819  58.345  1.00 143.11 ? 16  VAL C CB  1 
ATOM 4450 C CG1 . VAL C 3 16  ? 107.087 65.468  57.230  1.00 142.43 ? 16  VAL C CG1 1 
ATOM 4451 C CG2 . VAL C 3 16  ? 106.097 64.720  59.393  1.00 142.18 ? 16  VAL C CG2 1 
ATOM 4452 N N   . GLU C 3 17  ? 105.709 68.857  57.419  1.00 137.54 ? 17  GLU C N   1 
ATOM 4453 C CA  . GLU C 3 17  ? 105.885 69.885  56.398  1.00 137.73 ? 17  GLU C CA  1 
ATOM 4454 C C   . GLU C 3 17  ? 106.624 71.095  56.954  1.00 137.72 ? 17  GLU C C   1 
ATOM 4455 O O   . GLU C 3 17  ? 107.427 71.718  56.250  1.00 135.88 ? 17  GLU C O   1 
ATOM 4456 C CB  . GLU C 3 17  ? 104.528 70.298  55.830  1.00 137.27 ? 17  GLU C CB  1 
ATOM 4457 C CG  . GLU C 3 17  ? 104.611 71.230  54.633  1.00 138.68 ? 17  GLU C CG  1 
ATOM 4458 C CD  . GLU C 3 17  ? 105.158 70.545  53.395  1.00 139.19 ? 17  GLU C CD  1 
ATOM 4459 O OE1 . GLU C 3 17  ? 105.099 69.300  53.325  1.00 138.35 ? 17  GLU C OE1 1 
ATOM 4460 O OE2 . GLU C 3 17  ? 105.647 71.254  52.490  1.00 137.43 ? 17  GLU C OE2 1 
ATOM 4461 N N   . GLN C 3 18  ? 106.360 71.448  58.214  1.00 126.51 ? 18  GLN C N   1 
ATOM 4462 C CA  . GLN C 3 18  ? 107.062 72.572  58.826  1.00 124.24 ? 18  GLN C CA  1 
ATOM 4463 C C   . GLN C 3 18  ? 108.548 72.279  58.982  1.00 124.32 ? 18  GLN C C   1 
ATOM 4464 O O   . GLN C 3 18  ? 109.387 73.150  58.725  1.00 124.65 ? 18  GLN C O   1 
ATOM 4465 C CB  . GLN C 3 18  ? 106.436 72.910  60.179  1.00 121.14 ? 18  GLN C CB  1 
ATOM 4466 C CG  . GLN C 3 18  ? 107.202 73.955  60.975  1.00 121.59 ? 18  GLN C CG  1 
ATOM 4467 C CD  . GLN C 3 18  ? 107.265 75.298  60.276  1.00 121.41 ? 18  GLN C CD  1 
ATOM 4468 O OE1 . GLN C 3 18  ? 106.396 75.637  59.474  1.00 120.41 ? 18  GLN C OE1 1 
ATOM 4469 N NE2 . GLN C 3 18  ? 108.300 76.070  60.577  1.00 122.58 ? 18  GLN C NE2 1 
ATOM 4470 N N   . LEU C 3 19  ? 108.896 71.059  59.398  1.00 131.05 ? 19  LEU C N   1 
ATOM 4471 C CA  . LEU C 3 19  ? 110.302 70.718  59.582  1.00 129.90 ? 19  LEU C CA  1 
ATOM 4472 C C   . LEU C 3 19  ? 111.062 70.736  58.263  1.00 131.06 ? 19  LEU C C   1 
ATOM 4473 O O   . LEU C 3 19  ? 112.278 70.953  58.254  1.00 132.08 ? 19  LEU C O   1 
ATOM 4474 C CB  . LEU C 3 19  ? 110.432 69.353  60.255  1.00 131.42 ? 19  LEU C CB  1 
ATOM 4475 C CG  . LEU C 3 19  ? 109.904 69.260  61.686  1.00 131.65 ? 19  LEU C CG  1 
ATOM 4476 C CD1 . LEU C 3 19  ? 110.112 67.865  62.246  1.00 132.60 ? 19  LEU C CD1 1 
ATOM 4477 C CD2 . LEU C 3 19  ? 110.575 70.296  62.568  1.00 131.39 ? 19  LEU C CD2 1 
ATOM 4478 N N   . LYS C 3 20  ? 110.373 70.499  57.145  1.00 134.22 ? 20  LYS C N   1 
ATOM 4479 C CA  . LYS C 3 20  ? 111.028 70.603  55.845  1.00 134.91 ? 20  LYS C CA  1 
ATOM 4480 C C   . LYS C 3 20  ? 111.435 72.041  55.553  1.00 134.19 ? 20  LYS C C   1 
ATOM 4481 O O   . LYS C 3 20  ? 112.528 72.290  55.030  1.00 133.53 ? 20  LYS C O   1 
ATOM 4482 C CB  . LYS C 3 20  ? 110.106 70.077  54.746  1.00 134.90 ? 20  LYS C CB  1 
ATOM 4483 C CG  . LYS C 3 20  ? 109.773 68.600  54.860  1.00 134.91 ? 20  LYS C CG  1 
ATOM 4484 C CD  . LYS C 3 20  ? 108.886 68.150  53.710  1.00 134.53 ? 20  LYS C CD  1 
ATOM 4485 C CE  . LYS C 3 20  ? 108.569 66.667  53.801  1.00 135.41 ? 20  LYS C CE  1 
ATOM 4486 N NZ  . LYS C 3 20  ? 107.705 66.215  52.676  1.00 134.98 ? 20  LYS C NZ  1 
ATOM 4487 N N   . MET C 3 21  ? 110.567 73.000  55.883  1.00 124.44 ? 21  MET C N   1 
ATOM 4488 C CA  . MET C 3 21  ? 110.884 74.405  55.648  1.00 123.83 ? 21  MET C CA  1 
ATOM 4489 C C   . MET C 3 21  ? 112.063 74.857  56.501  1.00 122.82 ? 21  MET C C   1 
ATOM 4490 O O   . MET C 3 21  ? 112.929 75.601  56.027  1.00 122.56 ? 21  MET C O   1 
ATOM 4491 C CB  . MET C 3 21  ? 109.655 75.269  55.931  1.00 121.93 ? 21  MET C CB  1 
ATOM 4492 C CG  . MET C 3 21  ? 108.403 74.829  55.192  1.00 123.61 ? 21  MET C CG  1 
ATOM 4493 S SD  . MET C 3 21  ? 108.557 74.963  53.402  1.00 127.19 ? 21  MET C SD  1 
ATOM 4494 C CE  . MET C 3 21  ? 108.776 76.730  53.215  1.00 123.75 ? 21  MET C CE  1 
ATOM 4495 N N   . GLU C 3 22  ? 112.113 74.417  57.760  1.00 114.45 ? 22  GLU C N   1 
ATOM 4496 C CA  . GLU C 3 22  ? 113.190 74.835  58.649  1.00 114.11 ? 22  GLU C CA  1 
ATOM 4497 C C   . GLU C 3 22  ? 114.516 74.181  58.283  1.00 116.00 ? 22  GLU C C   1 
ATOM 4498 O O   . GLU C 3 22  ? 115.579 74.747  58.558  1.00 116.24 ? 22  GLU C O   1 
ATOM 4499 C CB  . GLU C 3 22  ? 112.826 74.515  60.098  1.00 113.74 ? 22  GLU C CB  1 
ATOM 4500 C CG  . GLU C 3 22  ? 111.535 75.161  60.568  1.00 114.10 ? 22  GLU C CG  1 
ATOM 4501 C CD  . GLU C 3 22  ? 111.168 74.768  61.984  1.00 113.10 ? 22  GLU C CD  1 
ATOM 4502 O OE1 . GLU C 3 22  ? 111.932 74.002  62.606  1.00 112.03 ? 22  GLU C OE1 1 
ATOM 4503 O OE2 . GLU C 3 22  ? 110.113 75.221  62.474  1.00 110.18 ? 22  GLU C OE2 1 
ATOM 4504 N N   . ALA C 3 23  ? 114.478 72.999  57.669  1.00 127.51 ? 23  ALA C N   1 
ATOM 4505 C CA  . ALA C 3 23  ? 115.697 72.286  57.310  1.00 126.21 ? 23  ALA C CA  1 
ATOM 4506 C C   . ALA C 3 23  ? 116.323 72.776  56.012  1.00 126.42 ? 23  ALA C C   1 
ATOM 4507 O O   . ALA C 3 23  ? 117.444 72.366  55.694  1.00 125.19 ? 23  ALA C O   1 
ATOM 4508 C CB  . ALA C 3 23  ? 115.417 70.786  57.204  1.00 125.93 ? 23  ALA C CB  1 
ATOM 4509 N N   . ASN C 3 24  ? 115.638 73.633  55.257  1.00 130.28 ? 24  ASN C N   1 
ATOM 4510 C CA  . ASN C 3 24  ? 116.122 74.090  53.962  1.00 130.02 ? 24  ASN C CA  1 
ATOM 4511 C C   . ASN C 3 24  ? 116.699 75.499  54.004  1.00 129.80 ? 24  ASN C C   1 
ATOM 4512 O O   . ASN C 3 24  ? 116.930 76.093  52.946  1.00 128.89 ? 24  ASN C O   1 
ATOM 4513 C CB  . ASN C 3 24  ? 115.000 74.018  52.924  1.00 130.73 ? 24  ASN C CB  1 
ATOM 4514 C CG  . ASN C 3 24  ? 114.710 72.599  52.477  1.00 131.48 ? 24  ASN C CG  1 
ATOM 4515 O OD1 . ASN C 3 24  ? 115.353 72.081  51.564  1.00 130.78 ? 24  ASN C OD1 1 
ATOM 4516 N ND2 . ASN C 3 24  ? 113.736 71.963  53.116  1.00 130.62 ? 24  ASN C ND2 1 
ATOM 4517 N N   . ILE C 3 25  ? 116.935 76.049  55.189  1.00 119.91 ? 25  ILE C N   1 
ATOM 4518 C CA  . ILE C 3 25  ? 117.477 77.393  55.307  1.00 118.81 ? 25  ILE C CA  1 
ATOM 4519 C C   . ILE C 3 25  ? 118.996 77.327  55.204  1.00 117.45 ? 25  ILE C C   1 
ATOM 4520 O O   . ILE C 3 25  ? 119.622 76.302  55.484  1.00 115.33 ? 25  ILE C O   1 
ATOM 4521 C CB  . ILE C 3 25  ? 117.041 78.077  56.618  1.00 116.41 ? 25  ILE C CB  1 
ATOM 4522 C CG1 . ILE C 3 25  ? 117.629 77.346  57.824  1.00 114.98 ? 25  ILE C CG1 1 
ATOM 4523 C CG2 . ILE C 3 25  ? 115.526 78.123  56.714  1.00 116.31 ? 25  ILE C CG2 1 
ATOM 4524 C CD1 . ILE C 3 25  ? 117.339 78.018  59.140  1.00 112.21 ? 25  ILE C CD1 1 
ATOM 4525 N N   . ASP C 3 26  ? 119.597 78.441  54.797  1.00 113.14 ? 26  ASP C N   1 
ATOM 4526 C CA  . ASP C 3 26  ? 121.046 78.546  54.703  1.00 114.11 ? 26  ASP C CA  1 
ATOM 4527 C C   . ASP C 3 26  ? 121.622 78.934  56.058  1.00 116.08 ? 26  ASP C C   1 
ATOM 4528 O O   . ASP C 3 26  ? 121.185 79.914  56.669  1.00 116.55 ? 26  ASP C O   1 
ATOM 4529 C CB  . ASP C 3 26  ? 121.443 79.573  53.642  1.00 114.20 ? 26  ASP C CB  1 
ATOM 4530 C CG  . ASP C 3 26  ? 122.945 79.728  53.515  1.00 116.51 ? 26  ASP C CG  1 
ATOM 4531 O OD1 . ASP C 3 26  ? 123.602 78.780  53.036  1.00 115.96 ? 26  ASP C OD1 1 
ATOM 4532 O OD2 . ASP C 3 26  ? 123.469 80.796  53.894  1.00 116.81 ? 26  ASP C OD2 1 
ATOM 4533 N N   . ARG C 3 27  ? 122.603 78.166  56.521  1.00 101.79 ? 27  ARG C N   1 
ATOM 4534 C CA  . ARG C 3 27  ? 123.241 78.389  57.811  1.00 100.26 ? 27  ARG C CA  1 
ATOM 4535 C C   . ARG C 3 27  ? 124.698 78.774  57.601  1.00 101.34 ? 27  ARG C C   1 
ATOM 4536 O O   . ARG C 3 27  ? 125.424 78.098  56.866  1.00 103.84 ? 27  ARG C O   1 
ATOM 4537 C CB  . ARG C 3 27  ? 123.143 77.142  58.690  1.00 98.91  ? 27  ARG C CB  1 
ATOM 4538 C CG  . ARG C 3 27  ? 121.719 76.740  59.036  1.00 99.45  ? 27  ARG C CG  1 
ATOM 4539 C CD  . ARG C 3 27  ? 121.682 75.411  59.770  1.00 101.10 ? 27  ARG C CD  1 
ATOM 4540 N NE  . ARG C 3 27  ? 120.330 75.043  60.170  1.00 102.93 ? 27  ARG C NE  1 
ATOM 4541 C CZ  . ARG C 3 27  ? 119.453 74.437  59.381  1.00 102.90 ? 27  ARG C CZ  1 
ATOM 4542 N NH1 . ARG C 3 27  ? 119.750 74.127  58.130  1.00 102.43 ? 27  ARG C NH1 1 
ATOM 4543 N NH2 . ARG C 3 27  ? 118.249 74.135  59.859  1.00 99.76  ? 27  ARG C NH2 1 
ATOM 4544 N N   . ILE C 3 28  ? 125.116 79.861  58.239  1.00 93.04  ? 28  ILE C N   1 
ATOM 4545 C CA  . ILE C 3 28  ? 126.510 80.276  58.234  1.00 92.00  ? 28  ILE C CA  1 
ATOM 4546 C C   . ILE C 3 28  ? 127.231 79.625  59.408  1.00 90.85  ? 28  ILE C C   1 
ATOM 4547 O O   . ILE C 3 28  ? 126.614 79.096  60.335  1.00 94.07  ? 28  ILE C O   1 
ATOM 4548 C CB  . ILE C 3 28  ? 126.649 81.810  58.283  1.00 90.21  ? 28  ILE C CB  1 
ATOM 4549 C CG1 . ILE C 3 28  ? 126.149 82.346  59.625  1.00 90.08  ? 28  ILE C CG1 1 
ATOM 4550 C CG2 . ILE C 3 28  ? 125.891 82.449  57.135  1.00 89.51  ? 28  ILE C CG2 1 
ATOM 4551 C CD1 . ILE C 3 28  ? 126.342 83.833  59.798  1.00 88.60  ? 28  ILE C CD1 1 
ATOM 4552 N N   . LYS C 3 29  ? 128.559 79.657  59.362  1.00 89.78  ? 29  LYS C N   1 
ATOM 4553 C CA  . LYS C 3 29  ? 129.357 79.083  60.434  1.00 92.04  ? 29  LYS C CA  1 
ATOM 4554 C C   . LYS C 3 29  ? 129.157 79.867  61.725  1.00 90.99  ? 29  LYS C C   1 
ATOM 4555 O O   . LYS C 3 29  ? 128.848 81.060  61.713  1.00 95.02  ? 29  LYS C O   1 
ATOM 4556 C CB  . LYS C 3 29  ? 130.839 79.082  60.060  1.00 92.72  ? 29  LYS C CB  1 
ATOM 4557 C CG  . LYS C 3 29  ? 131.218 78.116  58.951  1.00 93.47  ? 29  LYS C CG  1 
ATOM 4558 C CD  . LYS C 3 29  ? 131.151 76.680  59.434  1.00 93.01  ? 29  LYS C CD  1 
ATOM 4559 C CE  . LYS C 3 29  ? 131.566 75.710  58.345  1.00 92.10  ? 29  LYS C CE  1 
ATOM 4560 N NZ  . LYS C 3 29  ? 131.543 74.300  58.820  1.00 92.37  ? 29  LYS C NZ  1 
ATOM 4561 N N   . VAL C 3 30  ? 129.327 79.173  62.852  1.00 87.04  ? 30  VAL C N   1 
ATOM 4562 C CA  . VAL C 3 30  ? 129.195 79.827  64.151  1.00 87.68  ? 30  VAL C CA  1 
ATOM 4563 C C   . VAL C 3 30  ? 130.283 80.877  64.328  1.00 89.27  ? 30  VAL C C   1 
ATOM 4564 O O   . VAL C 3 30  ? 130.052 81.938  64.919  1.00 88.92  ? 30  VAL C O   1 
ATOM 4565 C CB  . VAL C 3 30  ? 129.221 78.779  65.279  1.00 88.32  ? 30  VAL C CB  1 
ATOM 4566 C CG1 . VAL C 3 30  ? 129.347 79.448  66.635  1.00 86.24  ? 30  VAL C CG1 1 
ATOM 4567 C CG2 . VAL C 3 30  ? 127.965 77.937  65.230  1.00 89.46  ? 30  VAL C CG2 1 
ATOM 4568 N N   . SER C 3 31  ? 131.479 80.608  63.800  1.00 91.84  ? 31  SER C N   1 
ATOM 4569 C CA  . SER C 3 31  ? 132.556 81.589  63.871  1.00 90.51  ? 31  SER C CA  1 
ATOM 4570 C C   . SER C 3 31  ? 132.185 82.864  63.125  1.00 90.32  ? 31  SER C C   1 
ATOM 4571 O O   . SER C 3 31  ? 132.482 83.971  63.588  1.00 92.44  ? 31  SER C O   1 
ATOM 4572 C CB  . SER C 3 31  ? 133.846 80.991  63.312  1.00 91.89  ? 31  SER C CB  1 
ATOM 4573 O OG  . SER C 3 31  ? 133.679 80.584  61.965  1.00 92.36  ? 31  SER C OG  1 
ATOM 4574 N N   . LYS C 3 32  ? 131.549 82.729  61.960  1.00 82.60  ? 32  LYS C N   1 
ATOM 4575 C CA  . LYS C 3 32  ? 131.079 83.906  61.237  1.00 83.20  ? 32  LYS C CA  1 
ATOM 4576 C C   . LYS C 3 32  ? 130.002 84.640  62.026  1.00 84.13  ? 32  LYS C C   1 
ATOM 4577 O O   . LYS C 3 32  ? 130.011 85.874  62.105  1.00 85.69  ? 32  LYS C O   1 
ATOM 4578 C CB  . LYS C 3 32  ? 130.554 83.499  59.861  1.00 83.09  ? 32  LYS C CB  1 
ATOM 4579 C CG  . LYS C 3 32  ? 130.017 84.650  59.034  1.00 84.34  ? 32  LYS C CG  1 
ATOM 4580 C CD  . LYS C 3 32  ? 131.093 85.685  58.767  1.00 85.51  ? 32  LYS C CD  1 
ATOM 4581 C CE  . LYS C 3 32  ? 130.561 86.822  57.913  1.00 86.13  ? 32  LYS C CE  1 
ATOM 4582 N NZ  . LYS C 3 32  ? 131.613 87.834  57.622  1.00 86.48  ? 32  LYS C NZ  1 
ATOM 4583 N N   . ALA C 3 33  ? 129.059 83.897  62.609  1.00 79.38  ? 33  ALA C N   1 
ATOM 4584 C CA  . ALA C 3 33  ? 128.007 84.519  63.406  1.00 75.12  ? 33  ALA C CA  1 
ATOM 4585 C C   . ALA C 3 33  ? 128.564 85.116  64.691  1.00 76.48  ? 33  ALA C C   1 
ATOM 4586 O O   . ALA C 3 33  ? 128.132 86.191  65.120  1.00 78.60  ? 33  ALA C O   1 
ATOM 4587 C CB  . ALA C 3 33  ? 126.915 83.500  63.720  1.00 78.52  ? 33  ALA C CB  1 
ATOM 4588 N N   . ALA C 3 34  ? 129.510 84.424  65.329  1.00 79.41  ? 34  ALA C N   1 
ATOM 4589 C CA  . ALA C 3 34  ? 130.113 84.946  66.551  1.00 78.05  ? 34  ALA C CA  1 
ATOM 4590 C C   . ALA C 3 34  ? 130.880 86.233  66.285  1.00 79.79  ? 34  ALA C C   1 
ATOM 4591 O O   . ALA C 3 34  ? 130.833 87.170  67.090  1.00 80.36  ? 34  ALA C O   1 
ATOM 4592 C CB  . ALA C 3 34  ? 131.029 83.896  67.176  1.00 74.87  ? 34  ALA C CB  1 
ATOM 4593 N N   . ALA C 3 35  ? 131.600 86.296  65.163  1.00 77.00  ? 35  ALA C N   1 
ATOM 4594 C CA  . ALA C 3 35  ? 132.375 87.490  64.846  1.00 73.10  ? 35  ALA C CA  1 
ATOM 4595 C C   . ALA C 3 35  ? 131.474 88.700  64.643  1.00 73.72  ? 35  ALA C C   1 
ATOM 4596 O O   . ALA C 3 35  ? 131.815 89.811  65.064  1.00 78.83  ? 35  ALA C O   1 
ATOM 4597 C CB  . ALA C 3 35  ? 133.230 87.247  63.604  1.00 71.34  ? 35  ALA C CB  1 
ATOM 4598 N N   . ASP C 3 36  ? 130.320 88.507  64.001  1.00 69.31  ? 36  ASP C N   1 
ATOM 4599 C CA  . ASP C 3 36  ? 129.410 89.622  63.760  1.00 65.22  ? 36  ASP C CA  1 
ATOM 4600 C C   . ASP C 3 36  ? 128.881 90.206  65.063  1.00 67.29  ? 36  ASP C C   1 
ATOM 4601 O O   . ASP C 3 36  ? 128.775 91.429  65.203  1.00 77.10  ? 36  ASP C O   1 
ATOM 4602 C CB  . ASP C 3 36  ? 128.255 89.171  62.868  1.00 71.43  ? 36  ASP C CB  1 
ATOM 4603 C CG  . ASP C 3 36  ? 128.718 88.728  61.495  1.00 77.24  ? 36  ASP C CG  1 
ATOM 4604 O OD1 . ASP C 3 36  ? 129.930 88.826  61.215  1.00 72.04  ? 36  ASP C OD1 1 
ATOM 4605 O OD2 . ASP C 3 36  ? 127.869 88.281  60.696  1.00 77.70  ? 36  ASP C OD2 1 
ATOM 4606 N N   . LEU C 3 37  ? 128.528 89.350  66.024  1.00 63.32  ? 37  LEU C N   1 
ATOM 4607 C CA  . LEU C 3 37  ? 128.087 89.850  67.322  1.00 62.87  ? 37  LEU C CA  1 
ATOM 4608 C C   . LEU C 3 37  ? 129.214 90.574  68.046  1.00 63.45  ? 37  LEU C C   1 
ATOM 4609 O O   . LEU C 3 37  ? 128.993 91.625  68.656  1.00 66.09  ? 37  LEU C O   1 
ATOM 4610 C CB  . LEU C 3 37  ? 127.557 88.701  68.176  1.00 62.94  ? 37  LEU C CB  1 
ATOM 4611 C CG  . LEU C 3 37  ? 126.287 88.026  67.668  1.00 66.88  ? 37  LEU C CG  1 
ATOM 4612 C CD1 . LEU C 3 37  ? 125.912 86.877  68.577  1.00 66.87  ? 37  LEU C CD1 1 
ATOM 4613 C CD2 . LEU C 3 37  ? 125.159 89.034  67.586  1.00 66.03  ? 37  LEU C CD2 1 
ATOM 4614 N N   . MET C 3 38  ? 130.425 90.020  67.997  1.00 68.28  ? 38  MET C N   1 
ATOM 4615 C CA  . MET C 3 38  ? 131.564 90.679  68.626  1.00 66.79  ? 38  MET C CA  1 
ATOM 4616 C C   . MET C 3 38  ? 131.906 91.981  67.913  1.00 64.89  ? 38  MET C C   1 
ATOM 4617 O O   . MET C 3 38  ? 132.269 92.971  68.557  1.00 69.66  ? 38  MET C O   1 
ATOM 4618 C CB  . MET C 3 38  ? 132.766 89.736  68.640  1.00 67.67  ? 38  MET C CB  1 
ATOM 4619 C CG  . MET C 3 38  ? 133.927 90.217  69.487  1.00 71.04  ? 38  MET C CG  1 
ATOM 4620 S SD  . MET C 3 38  ? 135.317 89.073  69.454  1.00 88.98  ? 38  MET C SD  1 
ATOM 4621 C CE  . MET C 3 38  ? 135.775 89.156  67.726  1.00 74.44  ? 38  MET C CE  1 
ATOM 4622 N N   . ALA C 3 39  ? 131.804 91.993  66.582  1.00 59.76  ? 39  ALA C N   1 
ATOM 4623 C CA  . ALA C 3 39  ? 132.089 93.205  65.821  1.00 59.38  ? 39  ALA C CA  1 
ATOM 4624 C C   . ALA C 3 39  ? 131.080 94.305  66.122  1.00 59.21  ? 39  ALA C C   1 
ATOM 4625 O O   . ALA C 3 39  ? 131.450 95.480  66.228  1.00 63.12  ? 39  ALA C O   1 
ATOM 4626 C CB  . ALA C 3 39  ? 132.108 92.896  64.325  1.00 55.16  ? 39  ALA C CB  1 
ATOM 4627 N N   . TYR C 3 40  ? 129.799 93.949  66.240  1.00 52.71  ? 40  TYR C N   1 
ATOM 4628 C CA  . TYR C 3 40  ? 128.769 94.953  66.485  1.00 43.02  ? 40  TYR C CA  1 
ATOM 4629 C C   . TYR C 3 40  ? 128.965 95.641  67.829  1.00 48.97  ? 40  TYR C C   1 
ATOM 4630 O O   . TYR C 3 40  ? 128.816 96.862  67.936  1.00 60.18  ? 40  TYR C O   1 
ATOM 4631 C CB  . TYR C 3 40  ? 127.387 94.303  66.427  1.00 46.88  ? 40  TYR C CB  1 
ATOM 4632 C CG  . TYR C 3 40  ? 126.239 95.264  66.625  1.00 48.86  ? 40  TYR C CG  1 
ATOM 4633 C CD1 . TYR C 3 40  ? 125.660 95.913  65.546  1.00 54.61  ? 40  TYR C CD1 1 
ATOM 4634 C CD2 . TYR C 3 40  ? 125.743 95.533  67.890  1.00 48.50  ? 40  TYR C CD2 1 
ATOM 4635 C CE1 . TYR C 3 40  ? 124.612 96.792  65.721  1.00 52.95  ? 40  TYR C CE1 1 
ATOM 4636 C CE2 . TYR C 3 40  ? 124.700 96.412  68.075  1.00 47.68  ? 40  TYR C CE2 1 
ATOM 4637 C CZ  . TYR C 3 40  ? 124.138 97.039  66.987  1.00 52.22  ? 40  TYR C CZ  1 
ATOM 4638 O OH  . TYR C 3 40  ? 123.095 97.916  67.166  1.00 51.32  ? 40  TYR C OH  1 
ATOM 4639 N N   . CYS C 3 41  ? 129.304 94.874  68.866  1.00 53.42  ? 41  CYS C N   1 
ATOM 4640 C CA  . CYS C 3 41  ? 129.529 95.466  70.180  1.00 58.19  ? 41  CYS C CA  1 
ATOM 4641 C C   . CYS C 3 41  ? 130.715 96.421  70.164  1.00 57.77  ? 41  CYS C C   1 
ATOM 4642 O O   . CYS C 3 41  ? 130.670 97.488  70.786  1.00 64.67  ? 41  CYS C O   1 
ATOM 4643 C CB  . CYS C 3 41  ? 129.733 94.366  71.220  1.00 58.70  ? 41  CYS C CB  1 
ATOM 4644 S SG  . CYS C 3 41  ? 128.326 93.257  71.403  1.00 67.41  ? 41  CYS C SG  1 
ATOM 4645 N N   . GLU C 3 42  ? 131.790 96.051  69.466  1.00 59.58  ? 42  GLU C N   1 
ATOM 4646 C CA  . GLU C 3 42  ? 132.963 96.916  69.403  1.00 62.86  ? 42  GLU C CA  1 
ATOM 4647 C C   . GLU C 3 42  ? 132.643 98.227  68.696  1.00 63.76  ? 42  GLU C C   1 
ATOM 4648 O O   . GLU C 3 42  ? 133.081 99.298  69.131  1.00 68.27  ? 42  GLU C O   1 
ATOM 4649 C CB  . GLU C 3 42  ? 134.109 96.190  68.702  1.00 63.33  ? 42  GLU C CB  1 
ATOM 4650 C CG  . GLU C 3 42  ? 135.397 96.985  68.627  1.00 67.31  ? 42  GLU C CG  1 
ATOM 4651 C CD  . GLU C 3 42  ? 136.540 96.178  68.048  1.00 73.04  ? 42  GLU C CD  1 
ATOM 4652 O OE1 . GLU C 3 42  ? 136.363 94.957  67.847  1.00 69.75  ? 42  GLU C OE1 1 
ATOM 4653 O OE2 . GLU C 3 42  ? 137.614 96.762  67.792  1.00 73.68  ? 42  GLU C OE2 1 
ATOM 4654 N N   . ALA C 3 43  ? 131.886 98.162  67.600  1.00 52.52  ? 43  ALA C N   1 
ATOM 4655 C CA  . ALA C 3 43  ? 131.595 99.363  66.826  1.00 55.43  ? 43  ALA C CA  1 
ATOM 4656 C C   . ALA C 3 43  ? 130.701 100.326 67.595  1.00 59.59  ? 43  ALA C C   1 
ATOM 4657 O O   . ALA C 3 43  ? 130.829 101.546 67.441  1.00 61.39  ? 43  ALA C O   1 
ATOM 4658 C CB  . ALA C 3 43  ? 130.950 98.988  65.494  1.00 49.67  ? 43  ALA C CB  1 
ATOM 4659 N N   . HIS C 3 44  ? 129.794 99.807  68.420  1.00 52.18  ? 44  HIS C N   1 
ATOM 4660 C CA  . HIS C 3 44  ? 128.838 100.629 69.149  1.00 49.98  ? 44  HIS C CA  1 
ATOM 4661 C C   . HIS C 3 44  ? 129.188 100.763 70.624  1.00 57.70  ? 44  HIS C C   1 
ATOM 4662 O O   . HIS C 3 44  ? 128.347 101.203 71.413  1.00 57.21  ? 44  HIS C O   1 
ATOM 4663 C CB  . HIS C 3 44  ? 127.428 100.058 68.992  1.00 44.60  ? 44  HIS C CB  1 
ATOM 4664 C CG  . HIS C 3 44  ? 126.941 100.042 67.577  1.00 51.98  ? 44  HIS C CG  1 
ATOM 4665 N ND1 . HIS C 3 44  ? 125.951 100.885 67.121  1.00 61.05  ? 44  HIS C ND1 1 
ATOM 4666 C CD2 . HIS C 3 44  ? 127.315 99.293  66.514  1.00 53.87  ? 44  HIS C CD2 1 
ATOM 4667 C CE1 . HIS C 3 44  ? 125.731 100.650 65.840  1.00 55.03  ? 44  HIS C CE1 1 
ATOM 4668 N NE2 . HIS C 3 44  ? 126.545 99.688  65.447  1.00 55.56  ? 44  HIS C NE2 1 
ATOM 4669 N N   . ALA C 3 45  ? 130.412 100.398 71.012  1.00 60.67  ? 45  ALA C N   1 
ATOM 4670 C CA  . ALA C 3 45  ? 130.792 100.421 72.421  1.00 61.31  ? 45  ALA C CA  1 
ATOM 4671 C C   . ALA C 3 45  ? 130.790 101.837 72.983  1.00 62.07  ? 45  ALA C C   1 
ATOM 4672 O O   . ALA C 3 45  ? 130.362 102.059 74.121  1.00 60.48  ? 45  ALA C O   1 
ATOM 4673 C CB  . ALA C 3 45  ? 132.166 99.778  72.604  1.00 57.30  ? 45  ALA C CB  1 
ATOM 4674 N N   . LYS C 3 46  ? 131.281 102.807 72.208  1.00 65.89  ? 46  LYS C N   1 
ATOM 4675 C CA  . LYS C 3 46  ? 131.429 104.161 72.730  1.00 66.69  ? 46  LYS C CA  1 
ATOM 4676 C C   . LYS C 3 46  ? 130.085 104.836 72.970  1.00 65.82  ? 46  LYS C C   1 
ATOM 4677 O O   . LYS C 3 46  ? 129.954 105.630 73.907  1.00 64.33  ? 46  LYS C O   1 
ATOM 4678 C CB  . LYS C 3 46  ? 132.277 105.001 71.777  1.00 66.17  ? 46  LYS C CB  1 
ATOM 4679 C CG  . LYS C 3 46  ? 133.703 104.505 71.623  1.00 68.92  ? 46  LYS C CG  1 
ATOM 4680 C CD  . LYS C 3 46  ? 134.419 104.465 72.964  1.00 70.90  ? 46  LYS C CD  1 
ATOM 4681 C CE  . LYS C 3 46  ? 135.839 103.942 72.817  1.00 70.32  ? 46  LYS C CE  1 
ATOM 4682 N NZ  . LYS C 3 46  ? 136.546 103.879 74.126  1.00 65.81  ? 46  LYS C NZ  1 
ATOM 4683 N N   . GLU C 3 47  ? 129.080 104.538 72.149  1.00 63.40  ? 47  GLU C N   1 
ATOM 4684 C CA  . GLU C 3 47  ? 127.761 105.135 72.300  1.00 63.41  ? 47  GLU C CA  1 
ATOM 4685 C C   . GLU C 3 47  ? 126.839 104.312 73.194  1.00 62.85  ? 47  GLU C C   1 
ATOM 4686 O O   . GLU C 3 47  ? 125.614 104.423 73.074  1.00 56.82  ? 47  GLU C O   1 
ATOM 4687 C CB  . GLU C 3 47  ? 127.121 105.359 70.928  1.00 60.71  ? 47  GLU C CB  1 
ATOM 4688 C CG  . GLU C 3 47  ? 127.221 104.182 69.978  1.00 63.64  ? 47  GLU C CG  1 
ATOM 4689 C CD  . GLU C 3 47  ? 126.655 104.501 68.608  1.00 67.42  ? 47  GLU C CD  1 
ATOM 4690 O OE1 . GLU C 3 47  ? 125.879 105.473 68.498  1.00 67.50  ? 47  GLU C OE1 1 
ATOM 4691 O OE2 . GLU C 3 47  ? 126.987 103.787 67.641  1.00 67.12  ? 47  GLU C OE2 1 
ATOM 4692 N N   . ASP C 3 48  ? 127.400 103.496 74.085  1.00 56.53  ? 48  ASP C N   1 
ATOM 4693 C CA  . ASP C 3 48  ? 126.624 102.725 75.051  1.00 45.37  ? 48  ASP C CA  1 
ATOM 4694 C C   . ASP C 3 48  ? 126.844 103.326 76.430  1.00 52.71  ? 48  ASP C C   1 
ATOM 4695 O O   . ASP C 3 48  ? 127.892 103.086 77.050  1.00 60.70  ? 48  ASP C O   1 
ATOM 4696 C CB  . ASP C 3 48  ? 127.039 101.251 75.032  1.00 44.65  ? 48  ASP C CB  1 
ATOM 4697 C CG  . ASP C 3 48  ? 126.105 100.368 75.842  1.00 55.28  ? 48  ASP C CG  1 
ATOM 4698 O OD1 . ASP C 3 48  ? 125.113 100.886 76.396  1.00 60.88  ? 48  ASP C OD1 1 
ATOM 4699 O OD2 . ASP C 3 48  ? 126.356 99.149  75.919  1.00 55.58  ? 48  ASP C OD2 1 
ATOM 4700 N N   . PRO C 3 49  ? 125.902 104.114 76.951  1.00 54.87  ? 49  PRO C N   1 
ATOM 4701 C CA  . PRO C 3 49  ? 126.111 104.731 78.269  1.00 44.91  ? 49  PRO C CA  1 
ATOM 4702 C C   . PRO C 3 49  ? 126.260 103.736 79.403  1.00 48.18  ? 49  PRO C C   1 
ATOM 4703 O O   . PRO C 3 49  ? 127.011 104.003 80.347  1.00 57.02  ? 49  PRO C O   1 
ATOM 4704 C CB  . PRO C 3 49  ? 124.858 105.599 78.447  1.00 44.95  ? 49  PRO C CB  1 
ATOM 4705 C CG  . PRO C 3 49  ? 124.365 105.842 77.064  1.00 56.42  ? 49  PRO C CG  1 
ATOM 4706 C CD  . PRO C 3 49  ? 124.671 104.593 76.304  1.00 57.39  ? 49  PRO C CD  1 
ATOM 4707 N N   . LEU C 3 50  ? 125.571 102.596 79.350  1.00 52.37  ? 50  LEU C N   1 
ATOM 4708 C CA  . LEU C 3 50  ? 125.693 101.620 80.429  1.00 45.20  ? 50  LEU C CA  1 
ATOM 4709 C C   . LEU C 3 50  ? 127.070 100.975 80.437  1.00 45.18  ? 50  LEU C C   1 
ATOM 4710 O O   . LEU C 3 50  ? 127.635 100.719 81.505  1.00 43.00  ? 50  LEU C O   1 
ATOM 4711 C CB  . LEU C 3 50  ? 124.600 100.562 80.311  1.00 49.18  ? 50  LEU C CB  1 
ATOM 4712 C CG  . LEU C 3 50  ? 123.168 101.074 80.443  1.00 42.69  ? 50  LEU C CG  1 
ATOM 4713 C CD1 . LEU C 3 50  ? 122.193 99.918  80.425  1.00 47.74  ? 50  LEU C CD1 1 
ATOM 4714 C CD2 . LEU C 3 50  ? 123.017 101.888 81.710  1.00 36.25  ? 50  LEU C CD2 1 
ATOM 4715 N N   . LEU C 3 51  ? 127.617 100.687 79.258  1.00 54.93  ? 51  LEU C N   1 
ATOM 4716 C CA  . LEU C 3 51  ? 128.961 100.127 79.184  1.00 57.28  ? 51  LEU C CA  1 
ATOM 4717 C C   . LEU C 3 51  ? 130.004 101.159 79.595  1.00 58.70  ? 51  LEU C C   1 
ATOM 4718 O O   . LEU C 3 51  ? 130.883 100.875 80.416  1.00 61.34  ? 51  LEU C O   1 
ATOM 4719 C CB  . LEU C 3 51  ? 129.229 99.616  77.770  1.00 56.65  ? 51  LEU C CB  1 
ATOM 4720 C CG  . LEU C 3 51  ? 130.486 98.781  77.567  1.00 52.81  ? 51  LEU C CG  1 
ATOM 4721 C CD1 . LEU C 3 51  ? 130.424 97.547  78.436  1.00 55.39  ? 51  LEU C CD1 1 
ATOM 4722 C CD2 . LEU C 3 51  ? 130.626 98.408  76.107  1.00 57.07  ? 51  LEU C CD2 1 
ATOM 4723 N N   . THR C 3 52  ? 129.917 102.365 79.041  1.00 60.24  ? 52  THR C N   1 
ATOM 4724 C CA  . THR C 3 52  ? 130.831 103.458 79.375  1.00 63.24  ? 52  THR C CA  1 
ATOM 4725 C C   . THR C 3 52  ? 130.019 104.617 79.931  1.00 65.44  ? 52  THR C C   1 
ATOM 4726 O O   . THR C 3 52  ? 129.448 105.404 79.154  1.00 66.46  ? 52  THR C O   1 
ATOM 4727 C CB  . THR C 3 52  ? 131.628 103.905 78.151  1.00 65.89  ? 52  THR C CB  1 
ATOM 4728 O OG1 . THR C 3 52  ? 130.732 104.427 77.163  1.00 64.26  ? 52  THR C OG1 1 
ATOM 4729 C CG2 . THR C 3 52  ? 132.398 102.734 77.561  1.00 65.26  ? 52  THR C CG2 1 
ATOM 4730 N N   . PRO C 3 53  ? 129.931 104.764 81.253  1.00 72.52  ? 53  PRO C N   1 
ATOM 4731 C CA  . PRO C 3 53  ? 129.093 105.824 81.826  1.00 72.48  ? 53  PRO C CA  1 
ATOM 4732 C C   . PRO C 3 53  ? 129.520 107.209 81.362  1.00 76.74  ? 53  PRO C C   1 
ATOM 4733 O O   . PRO C 3 53  ? 130.709 107.517 81.263  1.00 74.31  ? 53  PRO C O   1 
ATOM 4734 C CB  . PRO C 3 53  ? 129.283 105.647 83.336  1.00 72.25  ? 53  PRO C CB  1 
ATOM 4735 C CG  . PRO C 3 53  ? 130.569 104.910 83.475  1.00 74.55  ? 53  PRO C CG  1 
ATOM 4736 C CD  . PRO C 3 53  ? 130.640 104.001 82.291  1.00 71.42  ? 53  PRO C CD  1 
ATOM 4737 N N   . VAL C 3 54  ? 128.525 108.042 81.076  1.00 82.64  ? 54  VAL C N   1 
ATOM 4738 C CA  . VAL C 3 54  ? 128.740 109.388 80.555  1.00 81.93  ? 54  VAL C CA  1 
ATOM 4739 C C   . VAL C 3 54  ? 129.071 110.325 81.711  1.00 86.36  ? 54  VAL C C   1 
ATOM 4740 O O   . VAL C 3 54  ? 128.775 110.000 82.870  1.00 84.10  ? 54  VAL C O   1 
ATOM 4741 C CB  . VAL C 3 54  ? 127.509 109.878 79.776  1.00 81.42  ? 54  VAL C CB  1 
ATOM 4742 C CG1 . VAL C 3 54  ? 127.238 108.968 78.595  1.00 82.49  ? 54  VAL C CG1 1 
ATOM 4743 C CG2 . VAL C 3 54  ? 126.300 109.940 80.690  1.00 80.76  ? 54  VAL C CG2 1 
ATOM 4744 N N   . PRO C 3 55  ? 129.685 111.480 81.453  1.00 97.07  ? 55  PRO C N   1 
ATOM 4745 C CA  . PRO C 3 55  ? 129.894 112.454 82.528  1.00 93.39  ? 55  PRO C CA  1 
ATOM 4746 C C   . PRO C 3 55  ? 128.570 112.932 83.104  1.00 93.73  ? 55  PRO C C   1 
ATOM 4747 O O   . PRO C 3 55  ? 127.545 112.960 82.420  1.00 95.84  ? 55  PRO C O   1 
ATOM 4748 C CB  . PRO C 3 55  ? 130.645 113.595 81.833  1.00 92.20  ? 55  PRO C CB  1 
ATOM 4749 C CG  . PRO C 3 55  ? 131.311 112.949 80.671  1.00 92.45  ? 55  PRO C CG  1 
ATOM 4750 C CD  . PRO C 3 55  ? 130.367 111.879 80.210  1.00 91.88  ? 55  PRO C CD  1 
ATOM 4751 N N   . ALA C 3 56  ? 128.606 113.302 84.387  1.00 91.49  ? 56  ALA C N   1 
ATOM 4752 C CA  . ALA C 3 56  ? 127.386 113.687 85.090  1.00 93.26  ? 56  ALA C CA  1 
ATOM 4753 C C   . ALA C 3 56  ? 126.674 114.847 84.406  1.00 94.59  ? 56  ALA C C   1 
ATOM 4754 O O   . ALA C 3 56  ? 125.451 114.982 84.531  1.00 94.34  ? 56  ALA C O   1 
ATOM 4755 C CB  . ALA C 3 56  ? 127.707 114.043 86.541  1.00 89.52  ? 56  ALA C CB  1 
ATOM 4756 N N   . SER C 3 57  ? 127.414 115.697 83.690  1.00 89.21  ? 57  SER C N   1 
ATOM 4757 C CA  . SER C 3 57  ? 126.782 116.808 82.987  1.00 86.42  ? 57  SER C CA  1 
ATOM 4758 C C   . SER C 3 57  ? 125.879 116.322 81.861  1.00 87.36  ? 57  SER C C   1 
ATOM 4759 O O   . SER C 3 57  ? 124.891 116.987 81.532  1.00 90.43  ? 57  SER C O   1 
ATOM 4760 C CB  . SER C 3 57  ? 127.846 117.759 82.437  1.00 87.42  ? 57  SER C CB  1 
ATOM 4761 O OG  . SER C 3 57  ? 128.691 117.099 81.512  1.00 91.08  ? 57  SER C OG  1 
ATOM 4762 N N   . GLU C 3 58  ? 126.197 115.177 81.262  1.00 81.83  ? 58  GLU C N   1 
ATOM 4763 C CA  . GLU C 3 58  ? 125.428 114.634 80.151  1.00 86.09  ? 58  GLU C CA  1 
ATOM 4764 C C   . GLU C 3 58  ? 124.438 113.566 80.594  1.00 85.33  ? 58  GLU C C   1 
ATOM 4765 O O   . GLU C 3 58  ? 123.790 112.945 79.746  1.00 82.18  ? 58  GLU C O   1 
ATOM 4766 C CB  . GLU C 3 58  ? 126.369 114.064 79.089  1.00 87.57  ? 58  GLU C CB  1 
ATOM 4767 C CG  . GLU C 3 58  ? 127.298 115.092 78.468  1.00 86.84  ? 58  GLU C CG  1 
ATOM 4768 C CD  . GLU C 3 58  ? 128.222 114.489 77.430  1.00 90.80  ? 58  GLU C CD  1 
ATOM 4769 O OE1 . GLU C 3 58  ? 128.220 113.249 77.281  1.00 92.46  ? 58  GLU C OE1 1 
ATOM 4770 O OE2 . GLU C 3 58  ? 128.950 115.254 76.764  1.00 86.58  ? 58  GLU C OE2 1 
ATOM 4771 N N   . ASN C 3 59  ? 124.307 113.340 81.899  1.00 74.16  ? 59  ASN C N   1 
ATOM 4772 C CA  . ASN C 3 59  ? 123.434 112.303 82.424  1.00 69.66  ? 59  ASN C CA  1 
ATOM 4773 C C   . ASN C 3 59  ? 122.105 112.921 82.825  1.00 72.73  ? 59  ASN C C   1 
ATOM 4774 O O   . ASN C 3 59  ? 122.075 113.753 83.743  1.00 70.85  ? 59  ASN C O   1 
ATOM 4775 C CB  . ASN C 3 59  ? 124.082 111.608 83.618  1.00 67.95  ? 59  ASN C CB  1 
ATOM 4776 C CG  . ASN C 3 59  ? 123.233 110.486 84.168  1.00 71.70  ? 59  ASN C CG  1 
ATOM 4777 O OD1 . ASN C 3 59  ? 122.363 109.957 83.480  1.00 72.24  ? 59  ASN C OD1 1 
ATOM 4778 N ND2 . ASN C 3 59  ? 123.483 110.113 85.416  1.00 69.24  ? 59  ASN C ND2 1 
ATOM 4779 N N   . PRO C 3 60  ? 120.997 112.580 82.167  1.00 65.29  ? 60  PRO C N   1 
ATOM 4780 C CA  . PRO C 3 60  ? 119.701 113.148 82.567  1.00 56.03  ? 60  PRO C CA  1 
ATOM 4781 C C   . PRO C 3 60  ? 119.257 112.752 83.962  1.00 56.56  ? 60  PRO C C   1 
ATOM 4782 O O   . PRO C 3 60  ? 118.371 113.409 84.521  1.00 65.72  ? 60  PRO C O   1 
ATOM 4783 C CB  . PRO C 3 60  ? 118.738 112.598 81.508  1.00 58.62  ? 60  PRO C CB  1 
ATOM 4784 C CG  . PRO C 3 60  ? 119.602 112.233 80.354  1.00 64.53  ? 60  PRO C CG  1 
ATOM 4785 C CD  . PRO C 3 60  ? 120.891 111.772 80.944  1.00 65.97  ? 60  PRO C CD  1 
ATOM 4786 N N   . PHE C 3 61  ? 119.835 111.705 84.541  1.00 49.87  ? 61  PHE C N   1 
ATOM 4787 C CA  . PHE C 3 61  ? 119.403 111.156 85.821  1.00 51.34  ? 61  PHE C CA  1 
ATOM 4788 C C   . PHE C 3 61  ? 120.387 111.467 86.945  1.00 55.88  ? 61  PHE C C   1 
ATOM 4789 O O   . PHE C 3 61  ? 120.641 110.629 87.811  1.00 66.62  ? 61  PHE C O   1 
ATOM 4790 C CB  . PHE C 3 61  ? 119.181 109.650 85.709  1.00 52.86  ? 61  PHE C CB  1 
ATOM 4791 C CG  . PHE C 3 61  ? 118.133 109.264 84.704  1.00 54.85  ? 61  PHE C CG  1 
ATOM 4792 C CD1 . PHE C 3 61  ? 116.800 109.203 85.063  1.00 49.87  ? 61  PHE C CD1 1 
ATOM 4793 C CD2 . PHE C 3 61  ? 118.483 108.956 83.403  1.00 57.18  ? 61  PHE C CD2 1 
ATOM 4794 C CE1 . PHE C 3 61  ? 115.840 108.850 84.142  1.00 53.79  ? 61  PHE C CE1 1 
ATOM 4795 C CE2 . PHE C 3 61  ? 117.526 108.601 82.479  1.00 52.52  ? 61  PHE C CE2 1 
ATOM 4796 C CZ  . PHE C 3 61  ? 116.204 108.547 82.849  1.00 51.25  ? 61  PHE C CZ  1 
ATOM 4797 N N   . ARG C 3 62  ? 120.975 112.660 86.924  1.00 70.15  ? 62  ARG C N   1 
ATOM 4798 C CA  . ARG C 3 62  ? 121.897 113.105 87.972  1.00 73.86  ? 62  ARG C CA  1 
ATOM 4799 C C   . ARG C 3 62  ? 121.350 112.866 89.376  1.00 74.09  ? 62  ARG C C   1 
ATOM 4800 O O   . ARG C 3 62  ? 120.910 113.799 90.048  1.00 73.14  ? 62  ARG C O   1 
ATOM 4801 C CB  . ARG C 3 62  ? 122.214 114.591 87.804  1.00 75.63  ? 62  ARG C CB  1 
ATOM 4802 C CG  . ARG C 3 62  ? 122.789 114.954 86.455  1.00 71.20  ? 62  ARG C CG  1 
ATOM 4803 C CD  . ARG C 3 62  ? 122.846 116.457 86.264  1.00 74.69  ? 62  ARG C CD  1 
ATOM 4804 N NE  . ARG C 3 62  ? 123.026 116.818 84.863  1.00 79.31  ? 62  ARG C NE  1 
ATOM 4805 C CZ  . ARG C 3 62  ? 122.031 117.051 84.018  1.00 79.54  ? 62  ARG C CZ  1 
ATOM 4806 N NH1 . ARG C 3 62  ? 120.767 116.973 84.400  1.00 79.30  ? 62  ARG C NH1 1 
ATOM 4807 N NH2 . ARG C 3 62  ? 122.311 117.373 82.759  1.00 75.62  ? 62  ARG C NH2 1 
ATOM 4808 N N   . ASP D 4 1   ? 81.416  118.082 71.211  1.00 53.51  ? 1   ASP E N   1 
ATOM 4809 C CA  . ASP D 4 1   ? 82.655  118.755 70.848  1.00 56.87  ? 1   ASP E CA  1 
ATOM 4810 C C   . ASP D 4 1   ? 83.119  119.630 72.003  1.00 59.84  ? 1   ASP E C   1 
ATOM 4811 O O   . ASP D 4 1   ? 82.329  119.957 72.885  1.00 65.64  ? 1   ASP E O   1 
ATOM 4812 C CB  . ASP D 4 1   ? 82.455  119.596 69.586  1.00 57.03  ? 1   ASP E CB  1 
ATOM 4813 C CG  . ASP D 4 1   ? 83.762  120.064 68.982  1.00 63.57  ? 1   ASP E CG  1 
ATOM 4814 O OD1 . ASP D 4 1   ? 84.831  119.630 69.460  1.00 63.90  ? 1   ASP E OD1 1 
ATOM 4815 O OD2 . ASP D 4 1   ? 83.719  120.869 68.029  1.00 63.24  ? 1   ASP E OD2 1 
ATOM 4816 N N   . VAL D 4 2   ? 84.399  120.007 72.004  1.00 51.64  ? 2   VAL E N   1 
ATOM 4817 C CA  . VAL D 4 2   ? 84.919  120.840 73.080  1.00 48.55  ? 2   VAL E CA  1 
ATOM 4818 C C   . VAL D 4 2   ? 84.344  122.240 72.940  1.00 50.61  ? 2   VAL E C   1 
ATOM 4819 O O   . VAL D 4 2   ? 84.451  122.870 71.881  1.00 52.93  ? 2   VAL E O   1 
ATOM 4820 C CB  . VAL D 4 2   ? 86.454  120.866 73.056  1.00 49.83  ? 2   VAL E CB  1 
ATOM 4821 C CG1 . VAL D 4 2   ? 86.979  121.702 74.206  1.00 42.06  ? 2   VAL E CG1 1 
ATOM 4822 C CG2 . VAL D 4 2   ? 87.013  119.458 73.119  1.00 49.56  ? 2   VAL E CG2 1 
ATOM 4823 N N   . GLN D 4 3   ? 83.727  122.732 74.008  1.00 50.35  ? 3   GLN E N   1 
ATOM 4824 C CA  . GLN D 4 3   ? 83.091  124.038 73.991  1.00 48.55  ? 3   GLN E CA  1 
ATOM 4825 C C   . GLN D 4 3   ? 83.393  124.767 75.291  1.00 59.44  ? 3   GLN E C   1 
ATOM 4826 O O   . GLN D 4 3   ? 83.499  124.153 76.354  1.00 60.35  ? 3   GLN E O   1 
ATOM 4827 C CB  . GLN D 4 3   ? 81.579  123.916 73.778  1.00 51.42  ? 3   GLN E CB  1 
ATOM 4828 C CG  . GLN D 4 3   ? 80.910  125.205 73.347  1.00 63.54  ? 3   GLN E CG  1 
ATOM 4829 C CD  . GLN D 4 3   ? 79.462  125.005 72.958  1.00 65.22  ? 3   GLN E CD  1 
ATOM 4830 O OE1 . GLN D 4 3   ? 78.904  123.924 73.135  1.00 63.30  ? 3   GLN E OE1 1 
ATOM 4831 N NE2 . GLN D 4 3   ? 78.845  126.050 72.420  1.00 59.04  ? 3   GLN E NE2 1 
ATOM 4832 N N   . LEU D 4 4   ? 83.535  126.086 75.191  1.00 55.52  ? 4   LEU E N   1 
ATOM 4833 C CA  . LEU D 4 4   ? 83.702  126.953 76.354  1.00 51.61  ? 4   LEU E CA  1 
ATOM 4834 C C   . LEU D 4 4   ? 82.886  128.211 76.099  1.00 56.41  ? 4   LEU E C   1 
ATOM 4835 O O   . LEU D 4 4   ? 83.274  129.043 75.276  1.00 66.80  ? 4   LEU E O   1 
ATOM 4836 C CB  . LEU D 4 4   ? 85.171  127.301 76.592  1.00 53.29  ? 4   LEU E CB  1 
ATOM 4837 C CG  . LEU D 4 4   ? 86.118  126.201 77.067  1.00 50.04  ? 4   LEU E CG  1 
ATOM 4838 C CD1 . LEU D 4 4   ? 87.537  126.724 77.161  1.00 46.92  ? 4   LEU E CD1 1 
ATOM 4839 C CD2 . LEU D 4 4   ? 85.662  125.671 78.406  1.00 53.63  ? 4   LEU E CD2 1 
ATOM 4840 N N   . VAL D 4 5   ? 81.760  128.345 76.792  1.00 56.30  ? 5   VAL E N   1 
ATOM 4841 C CA  . VAL D 4 5   ? 80.835  129.456 76.594  1.00 59.64  ? 5   VAL E CA  1 
ATOM 4842 C C   . VAL D 4 5   ? 80.861  130.331 77.838  1.00 59.82  ? 5   VAL E C   1 
ATOM 4843 O O   . VAL D 4 5   ? 80.601  129.851 78.947  1.00 65.62  ? 5   VAL E O   1 
ATOM 4844 C CB  . VAL D 4 5   ? 79.410  128.965 76.300  1.00 59.82  ? 5   VAL E CB  1 
ATOM 4845 C CG1 . VAL D 4 5   ? 78.479  130.147 76.110  1.00 59.42  ? 5   VAL E CG1 1 
ATOM 4846 C CG2 . VAL D 4 5   ? 79.401  128.080 75.072  1.00 55.37  ? 5   VAL E CG2 1 
ATOM 4847 N N   . GLU D 4 6   ? 81.167  131.611 77.656  1.00 65.75  ? 6   GLU E N   1 
ATOM 4848 C CA  . GLU D 4 6   ? 81.182  132.568 78.750  1.00 67.91  ? 6   GLU E CA  1 
ATOM 4849 C C   . GLU D 4 6   ? 79.882  133.362 78.763  1.00 74.40  ? 6   GLU E C   1 
ATOM 4850 O O   . GLU D 4 6   ? 79.274  133.612 77.719  1.00 73.31  ? 6   GLU E O   1 
ATOM 4851 C CB  . GLU D 4 6   ? 82.366  133.529 78.634  1.00 69.14  ? 6   GLU E CB  1 
ATOM 4852 C CG  . GLU D 4 6   ? 83.734  132.870 78.635  1.00 67.84  ? 6   GLU E CG  1 
ATOM 4853 C CD  . GLU D 4 6   ? 84.180  132.461 77.248  1.00 73.90  ? 6   GLU E CD  1 
ATOM 4854 O OE1 . GLU D 4 6   ? 83.309  132.197 76.395  1.00 76.25  ? 6   GLU E OE1 1 
ATOM 4855 O OE2 . GLU D 4 6   ? 85.401  132.418 77.003  1.00 73.67  ? 6   GLU E OE2 1 
ATOM 4856 N N   . SER D 4 7   ? 79.463  133.763 79.960  1.00 75.72  ? 7   SER E N   1 
ATOM 4857 C CA  . SER D 4 7   ? 78.239  134.533 80.123  1.00 74.74  ? 7   SER E CA  1 
ATOM 4858 C C   . SER D 4 7   ? 78.357  135.387 81.376  1.00 76.21  ? 7   SER E C   1 
ATOM 4859 O O   . SER D 4 7   ? 79.250  135.194 82.205  1.00 78.47  ? 7   SER E O   1 
ATOM 4860 C CB  . SER D 4 7   ? 77.011  133.624 80.197  1.00 70.72  ? 7   SER E CB  1 
ATOM 4861 O OG  . SER D 4 7   ? 77.112  132.725 81.287  1.00 70.80  ? 7   SER E OG  1 
ATOM 4862 N N   . GLY D 4 8   ? 77.441  136.344 81.506  1.00 77.19  ? 8   GLY E N   1 
ATOM 4863 C CA  . GLY D 4 8   ? 77.418  137.244 82.637  1.00 77.74  ? 8   GLY E CA  1 
ATOM 4864 C C   . GLY D 4 8   ? 77.945  138.634 82.355  1.00 81.93  ? 8   GLY E C   1 
ATOM 4865 O O   . GLY D 4 8   ? 77.824  139.510 83.219  1.00 83.34  ? 8   GLY E O   1 
ATOM 4866 N N   . GLY D 4 9   ? 78.524  138.862 81.180  1.00 84.68  ? 9   GLY E N   1 
ATOM 4867 C CA  . GLY D 4 9   ? 79.010  140.179 80.839  1.00 85.49  ? 9   GLY E CA  1 
ATOM 4868 C C   . GLY D 4 9   ? 77.896  141.137 80.467  1.00 85.94  ? 9   GLY E C   1 
ATOM 4869 O O   . GLY D 4 9   ? 76.775  140.746 80.145  1.00 86.02  ? 9   GLY E O   1 
ATOM 4870 N N   . GLY D 4 10  ? 78.219  142.418 80.519  1.00 92.73  ? 10  GLY E N   1 
ATOM 4871 C CA  . GLY D 4 10  ? 77.261  143.452 80.189  1.00 92.41  ? 10  GLY E CA  1 
ATOM 4872 C C   . GLY D 4 10  ? 77.682  144.778 80.782  1.00 96.02  ? 10  GLY E C   1 
ATOM 4873 O O   . GLY D 4 10  ? 78.703  144.890 81.459  1.00 96.29  ? 10  GLY E O   1 
ATOM 4874 N N   . LEU D 4 11  ? 76.860  145.788 80.513  1.00 97.22  ? 11  LEU E N   1 
ATOM 4875 C CA  . LEU D 4 11  ? 77.168  147.137 80.966  1.00 95.77  ? 11  LEU E CA  1 
ATOM 4876 C C   . LEU D 4 11  ? 76.929  147.265 82.465  1.00 96.41  ? 11  LEU E C   1 
ATOM 4877 O O   . LEU D 4 11  ? 75.837  146.969 82.960  1.00 95.12  ? 11  LEU E O   1 
ATOM 4878 C CB  . LEU D 4 11  ? 76.330  148.157 80.196  1.00 94.36  ? 11  LEU E CB  1 
ATOM 4879 C CG  . LEU D 4 11  ? 76.728  149.629 80.319  1.00 96.95  ? 11  LEU E CG  1 
ATOM 4880 C CD1 . LEU D 4 11  ? 76.506  150.340 78.996  1.00 94.55  ? 11  LEU E CD1 1 
ATOM 4881 C CD2 . LEU D 4 11  ? 75.943  150.318 81.423  1.00 97.99  ? 11  LEU E CD2 1 
ATOM 4882 N N   . VAL D 4 12  ? 77.959  147.705 83.189  1.00 97.99  ? 12  VAL E N   1 
ATOM 4883 C CA  . VAL D 4 12  ? 77.897  147.879 84.633  1.00 96.83  ? 12  VAL E CA  1 
ATOM 4884 C C   . VAL D 4 12  ? 78.403  149.270 84.986  1.00 98.98  ? 12  VAL E C   1 
ATOM 4885 O O   . VAL D 4 12  ? 79.171  149.887 84.245  1.00 102.92 ? 12  VAL E O   1 
ATOM 4886 C CB  . VAL D 4 12  ? 78.717  146.813 85.389  1.00 95.29  ? 12  VAL E CB  1 
ATOM 4887 C CG1 . VAL D 4 12  ? 78.109  145.437 85.197  1.00 97.02  ? 12  VAL E CG1 1 
ATOM 4888 C CG2 . VAL D 4 12  ? 80.154  146.832 84.918  1.00 95.39  ? 12  VAL E CG2 1 
ATOM 4889 N N   . GLN D 4 13  ? 77.952  149.763 86.132  1.00 102.52 ? 13  GLN E N   1 
ATOM 4890 C CA  . GLN D 4 13  ? 78.404  151.053 86.623  1.00 103.29 ? 13  GLN E CA  1 
ATOM 4891 C C   . GLN D 4 13  ? 79.781  150.926 87.274  1.00 102.91 ? 13  GLN E C   1 
ATOM 4892 O O   . GLN D 4 13  ? 80.131  149.867 87.800  1.00 102.79 ? 13  GLN E O   1 
ATOM 4893 C CB  . GLN D 4 13  ? 77.406  151.619 87.627  1.00 102.21 ? 13  GLN E CB  1 
ATOM 4894 C CG  . GLN D 4 13  ? 76.051  151.954 87.027  1.00 104.84 ? 13  GLN E CG  1 
ATOM 4895 C CD  . GLN D 4 13  ? 76.123  153.072 86.005  1.00 106.57 ? 13  GLN E CD  1 
ATOM 4896 O OE1 . GLN D 4 13  ? 77.011  153.924 86.060  1.00 105.89 ? 13  GLN E OE1 1 
ATOM 4897 N NE2 . GLN D 4 13  ? 75.187  153.074 85.063  1.00 103.58 ? 13  GLN E NE2 1 
ATOM 4898 N N   . PRO D 4 14  ? 80.584  151.990 87.240  1.00 100.90 ? 14  PRO E N   1 
ATOM 4899 C CA  . PRO D 4 14  ? 81.882  151.951 87.925  1.00 100.23 ? 14  PRO E CA  1 
ATOM 4900 C C   . PRO D 4 14  ? 81.707  151.700 89.414  1.00 100.76 ? 14  PRO E C   1 
ATOM 4901 O O   . PRO D 4 14  ? 80.781  152.211 90.046  1.00 104.71 ? 14  PRO E O   1 
ATOM 4902 C CB  . PRO D 4 14  ? 82.470  153.339 87.651  1.00 100.80 ? 14  PRO E CB  1 
ATOM 4903 C CG  . PRO D 4 14  ? 81.785  153.800 86.414  1.00 102.18 ? 14  PRO E CG  1 
ATOM 4904 C CD  . PRO D 4 14  ? 80.397  153.239 86.485  1.00 101.52 ? 14  PRO E CD  1 
ATOM 4905 N N   . GLY D 4 15  ? 82.614  150.903 89.973  1.00 94.05  ? 15  GLY E N   1 
ATOM 4906 C CA  . GLY D 4 15  ? 82.531  150.512 91.363  1.00 92.17  ? 15  GLY E CA  1 
ATOM 4907 C C   . GLY D 4 15  ? 81.549  149.401 91.656  1.00 94.18  ? 15  GLY E C   1 
ATOM 4908 O O   . GLY D 4 15  ? 81.369  149.050 92.829  1.00 93.04  ? 15  GLY E O   1 
ATOM 4909 N N   . GLY D 4 16  ? 80.910  148.834 90.635  1.00 94.27  ? 16  GLY E N   1 
ATOM 4910 C CA  . GLY D 4 16  ? 79.934  147.782 90.817  1.00 91.95  ? 16  GLY E CA  1 
ATOM 4911 C C   . GLY D 4 16  ? 80.582  146.412 90.874  1.00 93.04  ? 16  GLY E C   1 
ATOM 4912 O O   . GLY D 4 16  ? 81.804  146.266 90.931  1.00 95.33  ? 16  GLY E O   1 
ATOM 4913 N N   . SER D 4 17  ? 79.734  145.389 90.867  1.00 84.00  ? 17  SER E N   1 
ATOM 4914 C CA  . SER D 4 17  ? 80.184  144.007 90.927  1.00 84.53  ? 17  SER E CA  1 
ATOM 4915 C C   . SER D 4 17  ? 79.488  143.201 89.841  1.00 84.65  ? 17  SER E C   1 
ATOM 4916 O O   . SER D 4 17  ? 78.328  143.454 89.506  1.00 85.43  ? 17  SER E O   1 
ATOM 4917 C CB  . SER D 4 17  ? 79.906  143.382 92.300  1.00 86.10  ? 17  SER E CB  1 
ATOM 4918 O OG  . SER D 4 17  ? 80.556  144.103 93.331  1.00 87.81  ? 17  SER E OG  1 
ATOM 4919 N N   . ARG D 4 18  ? 80.212  142.230 89.289  1.00 81.78  ? 18  ARG E N   1 
ATOM 4920 C CA  . ARG D 4 18  ? 79.666  141.378 88.245  1.00 78.34  ? 18  ARG E CA  1 
ATOM 4921 C C   . ARG D 4 18  ? 80.272  139.988 88.365  1.00 81.08  ? 18  ARG E C   1 
ATOM 4922 O O   . ARG D 4 18  ? 81.424  139.830 88.776  1.00 85.43  ? 18  ARG E O   1 
ATOM 4923 C CB  . ARG D 4 18  ? 79.927  141.965 86.854  1.00 79.97  ? 18  ARG E CB  1 
ATOM 4924 C CG  . ARG D 4 18  ? 79.051  141.377 85.767  1.00 79.86  ? 18  ARG E CG  1 
ATOM 4925 C CD  . ARG D 4 18  ? 77.594  141.385 86.193  1.00 79.09  ? 18  ARG E CD  1 
ATOM 4926 N NE  . ARG D 4 18  ? 76.708  140.912 85.138  1.00 85.61  ? 18  ARG E NE  1 
ATOM 4927 C CZ  . ARG D 4 18  ? 75.988  141.704 84.356  1.00 85.86  ? 18  ARG E CZ  1 
ATOM 4928 N NH1 . ARG D 4 18  ? 76.015  143.019 84.493  1.00 82.33  ? 18  ARG E NH1 1 
ATOM 4929 N NH2 . ARG D 4 18  ? 75.219  141.163 83.416  1.00 81.28  ? 18  ARG E NH2 1 
ATOM 4930 N N   . LYS D 4 19  ? 79.480  138.982 88.004  1.00 74.62  ? 19  LYS E N   1 
ATOM 4931 C CA  . LYS D 4 19  ? 79.862  137.579 88.117  1.00 73.49  ? 19  LYS E CA  1 
ATOM 4932 C C   . LYS D 4 19  ? 79.923  136.966 86.726  1.00 77.75  ? 19  LYS E C   1 
ATOM 4933 O O   . LYS D 4 19  ? 78.905  136.905 86.028  1.00 74.58  ? 19  LYS E O   1 
ATOM 4934 C CB  . LYS D 4 19  ? 78.869  136.818 88.995  1.00 70.62  ? 19  LYS E CB  1 
ATOM 4935 C CG  . LYS D 4 19  ? 79.157  135.337 89.131  1.00 72.24  ? 19  LYS E CG  1 
ATOM 4936 C CD  . LYS D 4 19  ? 80.418  135.100 89.936  1.00 72.14  ? 19  LYS E CD  1 
ATOM 4937 C CE  . LYS D 4 19  ? 80.565  133.637 90.301  1.00 71.29  ? 19  LYS E CE  1 
ATOM 4938 N NZ  . LYS D 4 19  ? 79.395  133.136 91.070  1.00 73.96  ? 19  LYS E NZ  1 
ATOM 4939 N N   . LEU D 4 20  ? 81.109  136.515 86.324  1.00 70.37  ? 20  LEU E N   1 
ATOM 4940 C CA  . LEU D 4 20  ? 81.304  135.873 85.031  1.00 66.78  ? 20  LEU E CA  1 
ATOM 4941 C C   . LEU D 4 20  ? 81.315  134.360 85.188  1.00 65.52  ? 20  LEU E C   1 
ATOM 4942 O O   . LEU D 4 20  ? 81.915  133.826 86.124  1.00 67.41  ? 20  LEU E O   1 
ATOM 4943 C CB  . LEU D 4 20  ? 82.609  136.329 84.379  1.00 63.43  ? 20  LEU E CB  1 
ATOM 4944 C CG  . LEU D 4 20  ? 82.713  137.791 83.954  1.00 67.78  ? 20  LEU E CG  1 
ATOM 4945 C CD1 . LEU D 4 20  ? 84.042  138.030 83.272  1.00 66.97  ? 20  LEU E CD1 1 
ATOM 4946 C CD2 . LEU D 4 20  ? 81.566  138.170 83.041  1.00 65.34  ? 20  LEU E CD2 1 
ATOM 4947 N N   . SER D 4 21  ? 80.648  133.673 84.265  1.00 65.60  ? 21  SER E N   1 
ATOM 4948 C CA  . SER D 4 21  ? 80.559  132.221 84.265  1.00 68.58  ? 21  SER E CA  1 
ATOM 4949 C C   . SER D 4 21  ? 81.124  131.674 82.963  1.00 71.09  ? 21  SER E C   1 
ATOM 4950 O O   . SER D 4 21  ? 80.968  132.287 81.903  1.00 66.71  ? 21  SER E O   1 
ATOM 4951 C CB  . SER D 4 21  ? 79.111  131.752 84.440  1.00 69.66  ? 21  SER E CB  1 
ATOM 4952 O OG  . SER D 4 21  ? 78.558  132.229 85.653  1.00 72.27  ? 21  SER E OG  1 
ATOM 4953 N N   . CYS D 4 22  ? 81.782  130.520 83.050  1.00 66.52  ? 22  CYS E N   1 
ATOM 4954 C CA  . CYS D 4 22  ? 82.312  129.810 81.890  1.00 56.51  ? 22  CYS E CA  1 
ATOM 4955 C C   . CYS D 4 22  ? 81.882  128.354 81.987  1.00 64.10  ? 22  CYS E C   1 
ATOM 4956 O O   . CYS D 4 22  ? 82.420  127.601 82.803  1.00 68.92  ? 22  CYS E O   1 
ATOM 4957 C CB  . CYS D 4 22  ? 83.834  129.928 81.817  1.00 63.11  ? 22  CYS E CB  1 
ATOM 4958 S SG  . CYS D 4 22  ? 84.628  128.804 80.644  1.00 85.07  ? 22  CYS E SG  1 
ATOM 4959 N N   . SER D 4 23  ? 80.922  127.956 81.156  1.00 62.55  ? 23  SER E N   1 
ATOM 4960 C CA  . SER D 4 23  ? 80.430  126.585 81.149  1.00 59.28  ? 23  SER E CA  1 
ATOM 4961 C C   . SER D 4 23  ? 81.237  125.750 80.164  1.00 58.94  ? 23  SER E C   1 
ATOM 4962 O O   . SER D 4 23  ? 81.391  126.129 79.000  1.00 69.64  ? 23  SER E O   1 
ATOM 4963 C CB  . SER D 4 23  ? 78.949  126.548 80.777  1.00 59.43  ? 23  SER E CB  1 
ATOM 4964 O OG  . SER D 4 23  ? 78.183  127.338 81.668  1.00 68.13  ? 23  SER E OG  1 
ATOM 4965 N N   . ALA D 4 24  ? 81.734  124.610 80.631  1.00 48.04  ? 24  ALA E N   1 
ATOM 4966 C CA  . ALA D 4 24  ? 82.586  123.737 79.840  1.00 53.14  ? 24  ALA E CA  1 
ATOM 4967 C C   . ALA D 4 24  ? 81.852  122.453 79.484  1.00 59.02  ? 24  ALA E C   1 
ATOM 4968 O O   . ALA D 4 24  ? 81.189  121.849 80.332  1.00 59.79  ? 24  ALA E O   1 
ATOM 4969 C CB  . ALA D 4 24  ? 83.873  123.404 80.595  1.00 48.38  ? 24  ALA E CB  1 
ATOM 4970 N N   . SER D 4 25  ? 81.972  122.042 78.224  1.00 56.12  ? 25  SER E N   1 
ATOM 4971 C CA  . SER D 4 25  ? 81.397  120.791 77.758  1.00 52.96  ? 25  SER E CA  1 
ATOM 4972 C C   . SER D 4 25  ? 82.345  120.128 76.770  1.00 54.19  ? 25  SER E C   1 
ATOM 4973 O O   . SER D 4 25  ? 83.089  120.802 76.055  1.00 59.92  ? 25  SER E O   1 
ATOM 4974 C CB  . SER D 4 25  ? 80.030  121.013 77.102  1.00 54.85  ? 25  SER E CB  1 
ATOM 4975 O OG  . SER D 4 25  ? 80.139  121.891 75.996  1.00 54.65  ? 25  SER E OG  1 
ATOM 4976 N N   . GLY D 4 26  ? 82.308  118.800 76.734  1.00 48.07  ? 26  GLY E N   1 
ATOM 4977 C CA  . GLY D 4 26  ? 83.081  118.048 75.769  1.00 47.87  ? 26  GLY E CA  1 
ATOM 4978 C C   . GLY D 4 26  ? 84.503  117.712 76.152  1.00 51.30  ? 26  GLY E C   1 
ATOM 4979 O O   . GLY D 4 26  ? 85.239  117.187 75.310  1.00 52.01  ? 26  GLY E O   1 
ATOM 4980 N N   . PHE D 4 27  ? 84.922  117.995 77.383  1.00 42.36  ? 27  PHE E N   1 
ATOM 4981 C CA  . PHE D 4 27  ? 86.255  117.610 77.817  1.00 36.14  ? 27  PHE E CA  1 
ATOM 4982 C C   . PHE D 4 27  ? 86.269  117.467 79.331  1.00 39.65  ? 27  PHE E C   1 
ATOM 4983 O O   . PHE D 4 27  ? 85.349  117.903 80.026  1.00 41.09  ? 27  PHE E O   1 
ATOM 4984 C CB  . PHE D 4 27  ? 87.320  118.614 77.352  1.00 39.44  ? 27  PHE E CB  1 
ATOM 4985 C CG  . PHE D 4 27  ? 87.290  119.925 78.079  1.00 41.78  ? 27  PHE E CG  1 
ATOM 4986 C CD1 . PHE D 4 27  ? 86.390  120.910 77.721  1.00 37.66  ? 27  PHE E CD1 1 
ATOM 4987 C CD2 . PHE D 4 27  ? 88.182  120.183 79.104  1.00 42.13  ? 27  PHE E CD2 1 
ATOM 4988 C CE1 . PHE D 4 27  ? 86.367  122.116 78.382  1.00 44.00  ? 27  PHE E CE1 1 
ATOM 4989 C CE2 . PHE D 4 27  ? 88.162  121.389 79.769  1.00 43.55  ? 27  PHE E CE2 1 
ATOM 4990 C CZ  . PHE D 4 27  ? 87.255  122.355 79.408  1.00 45.81  ? 27  PHE E CZ  1 
ATOM 4991 N N   . ALA D 4 28  ? 87.323  116.825 79.831  1.00 43.50  ? 28  ALA E N   1 
ATOM 4992 C CA  . ALA D 4 28  ? 87.470  116.594 81.260  1.00 42.06  ? 28  ALA E CA  1 
ATOM 4993 C C   . ALA D 4 28  ? 87.803  117.894 81.978  1.00 46.25  ? 28  ALA E C   1 
ATOM 4994 O O   . ALA D 4 28  ? 88.975  118.254 82.111  1.00 49.42  ? 28  ALA E O   1 
ATOM 4995 C CB  . ALA D 4 28  ? 88.554  115.548 81.520  1.00 35.18  ? 28  ALA E CB  1 
ATOM 4996 N N   . PHE D 4 29  ? 86.773  118.596 82.454  1.00 45.62  ? 29  PHE E N   1 
ATOM 4997 C CA  . PHE D 4 29  ? 86.971  119.932 83.006  1.00 45.97  ? 29  PHE E CA  1 
ATOM 4998 C C   . PHE D 4 29  ? 87.864  119.903 84.239  1.00 45.28  ? 29  PHE E C   1 
ATOM 4999 O O   . PHE D 4 29  ? 88.722  120.775 84.413  1.00 53.61  ? 29  PHE E O   1 
ATOM 5000 C CB  . PHE D 4 29  ? 85.617  120.559 83.334  1.00 50.15  ? 29  PHE E CB  1 
ATOM 5001 C CG  . PHE D 4 29  ? 85.710  121.906 83.989  1.00 49.80  ? 29  PHE E CG  1 
ATOM 5002 C CD1 . PHE D 4 29  ? 86.046  123.025 83.253  1.00 48.84  ? 29  PHE E CD1 1 
ATOM 5003 C CD2 . PHE D 4 29  ? 85.448  122.055 85.338  1.00 50.31  ? 29  PHE E CD2 1 
ATOM 5004 C CE1 . PHE D 4 29  ? 86.125  124.262 83.848  1.00 46.83  ? 29  PHE E CE1 1 
ATOM 5005 C CE2 . PHE D 4 29  ? 85.527  123.291 85.937  1.00 50.27  ? 29  PHE E CE2 1 
ATOM 5006 C CZ  . PHE D 4 29  ? 85.866  124.395 85.191  1.00 46.88  ? 29  PHE E CZ  1 
ATOM 5007 N N   . SER D 4 30  ? 87.677  118.911 85.110  1.00 46.08  ? 30  SER E N   1 
ATOM 5008 C CA  . SER D 4 30  ? 88.447  118.847 86.346  1.00 53.07  ? 30  SER E CA  1 
ATOM 5009 C C   . SER D 4 30  ? 89.924  118.572 86.106  1.00 54.97  ? 30  SER E C   1 
ATOM 5010 O O   . SER D 4 30  ? 90.736  118.807 87.006  1.00 55.41  ? 30  SER E O   1 
ATOM 5011 C CB  . SER D 4 30  ? 87.871  117.773 87.265  1.00 52.63  ? 30  SER E CB  1 
ATOM 5012 O OG  . SER D 4 30  ? 87.950  116.494 86.662  1.00 52.09  ? 30  SER E OG  1 
ATOM 5013 N N   . SER D 4 31  ? 90.289  118.079 84.926  1.00 41.18  ? 31  SER E N   1 
ATOM 5014 C CA  . SER D 4 31  ? 91.676  117.773 84.607  1.00 38.83  ? 31  SER E CA  1 
ATOM 5015 C C   . SER D 4 31  ? 92.450  118.967 84.068  1.00 48.79  ? 31  SER E C   1 
ATOM 5016 O O   . SER D 4 31  ? 93.679  118.894 83.972  1.00 44.81  ? 31  SER E O   1 
ATOM 5017 C CB  . SER D 4 31  ? 91.733  116.632 83.590  1.00 47.27  ? 31  SER E CB  1 
ATOM 5018 O OG  . SER D 4 31  ? 91.061  115.488 84.081  1.00 53.75  ? 31  SER E OG  1 
ATOM 5019 N N   . PHE D 4 32  ? 91.772  120.051 83.713  1.00 44.62  ? 32  PHE E N   1 
ATOM 5020 C CA  . PHE D 4 32  ? 92.398  121.202 83.082  1.00 41.45  ? 32  PHE E CA  1 
ATOM 5021 C C   . PHE D 4 32  ? 92.492  122.361 84.062  1.00 46.71  ? 32  PHE E C   1 
ATOM 5022 O O   . PHE D 4 32  ? 91.537  122.654 84.786  1.00 54.30  ? 32  PHE E O   1 
ATOM 5023 C CB  . PHE D 4 32  ? 91.609  121.646 81.848  1.00 32.87  ? 32  PHE E CB  1 
ATOM 5024 C CG  . PHE D 4 32  ? 91.840  120.794 80.638  1.00 35.10  ? 32  PHE E CG  1 
ATOM 5025 C CD1 . PHE D 4 32  ? 91.249  119.552 80.528  1.00 34.66  ? 32  PHE E CD1 1 
ATOM 5026 C CD2 . PHE D 4 32  ? 92.635  121.241 79.604  1.00 46.64  ? 32  PHE E CD2 1 
ATOM 5027 C CE1 . PHE D 4 32  ? 91.455  118.770 79.422  1.00 33.53  ? 32  PHE E CE1 1 
ATOM 5028 C CE2 . PHE D 4 32  ? 92.844  120.460 78.491  1.00 48.32  ? 32  PHE E CE2 1 
ATOM 5029 C CZ  . PHE D 4 32  ? 92.251  119.223 78.401  1.00 44.07  ? 32  PHE E CZ  1 
ATOM 5030 N N   . GLY D 4 33  ? 93.649  123.014 84.086  1.00 46.30  ? 33  GLY E N   1 
ATOM 5031 C CA  . GLY D 4 33  ? 93.724  124.338 84.662  1.00 38.04  ? 33  GLY E CA  1 
ATOM 5032 C C   . GLY D 4 33  ? 93.029  125.349 83.773  1.00 31.63  ? 33  GLY E C   1 
ATOM 5033 O O   . GLY D 4 33  ? 92.936  125.185 82.560  1.00 45.87  ? 33  GLY E O   1 
ATOM 5034 N N   . MET D 4 34  ? 92.536  126.418 84.386  1.00 33.94  ? 34  MET E N   1 
ATOM 5035 C CA  . MET D 4 34  ? 91.739  127.401 83.671  1.00 37.61  ? 34  MET E CA  1 
ATOM 5036 C C   . MET D 4 34  ? 92.309  128.791 83.888  1.00 37.49  ? 34  MET E C   1 
ATOM 5037 O O   . MET D 4 34  ? 92.715  129.140 84.998  1.00 49.52  ? 34  MET E O   1 
ATOM 5038 C CB  . MET D 4 34  ? 90.278  127.365 84.123  1.00 29.85  ? 34  MET E CB  1 
ATOM 5039 C CG  . MET D 4 34  ? 89.642  125.994 84.042  1.00 40.06  ? 34  MET E CG  1 
ATOM 5040 S SD  . MET D 4 34  ? 89.647  125.301 82.383  1.00 55.70  ? 34  MET E SD  1 
ATOM 5041 C CE  . MET D 4 34  ? 88.618  126.485 81.524  1.00 34.54  ? 34  MET E CE  1 
ATOM 5042 N N   . HIS D 4 35  ? 92.331  129.580 82.820  1.00 31.92  ? 35  HIS E N   1 
ATOM 5043 C CA  . HIS D 4 35  ? 92.774  130.961 82.869  1.00 30.04  ? 35  HIS E CA  1 
ATOM 5044 C C   . HIS D 4 35  ? 91.652  131.873 82.405  1.00 28.19  ? 35  HIS E C   1 
ATOM 5045 O O   . HIS D 4 35  ? 90.820  131.493 81.579  1.00 43.99  ? 35  HIS E O   1 
ATOM 5046 C CB  . HIS D 4 35  ? 94.001  131.198 81.987  1.00 30.23  ? 35  HIS E CB  1 
ATOM 5047 C CG  . HIS D 4 35  ? 95.175  130.342 82.334  1.00 18.91  ? 35  HIS E CG  1 
ATOM 5048 N ND1 . HIS D 4 35  ? 96.308  130.842 82.937  1.00 34.77  ? 35  HIS E ND1 1 
ATOM 5049 C CD2 . HIS D 4 35  ? 95.399  129.022 82.148  1.00 22.78  ? 35  HIS E CD2 1 
ATOM 5050 C CE1 . HIS D 4 35  ? 97.177  129.864 83.114  1.00 38.17  ? 35  HIS E CE1 1 
ATOM 5051 N NE2 . HIS D 4 35  ? 96.649  128.749 82.644  1.00 31.03  ? 35  HIS E NE2 1 
ATOM 5052 N N   . TRP D 4 36  ? 91.639  133.084 82.941  1.00 35.11  ? 36  TRP E N   1 
ATOM 5053 C CA  . TRP D 4 36  ? 90.869  134.178 82.376  1.00 32.90  ? 36  TRP E CA  1 
ATOM 5054 C C   . TRP D 4 36  ? 91.829  135.124 81.678  1.00 46.84  ? 36  TRP E C   1 
ATOM 5055 O O   . TRP D 4 36  ? 92.805  135.578 82.280  1.00 61.99  ? 36  TRP E O   1 
ATOM 5056 C CB  . TRP D 4 36  ? 90.079  134.921 83.451  1.00 40.96  ? 36  TRP E CB  1 
ATOM 5057 C CG  . TRP D 4 36  ? 88.822  134.230 83.855  1.00 46.78  ? 36  TRP E CG  1 
ATOM 5058 C CD1 . TRP D 4 36  ? 88.621  133.490 84.977  1.00 45.10  ? 36  TRP E CD1 1 
ATOM 5059 C CD2 . TRP D 4 36  ? 87.588  134.212 83.134  1.00 46.76  ? 36  TRP E CD2 1 
ATOM 5060 N NE1 . TRP D 4 36  ? 87.336  133.012 85.005  1.00 44.35  ? 36  TRP E NE1 1 
ATOM 5061 C CE2 . TRP D 4 36  ? 86.680  133.442 83.883  1.00 34.68  ? 36  TRP E CE2 1 
ATOM 5062 C CE3 . TRP D 4 36  ? 87.161  134.773 81.929  1.00 49.75  ? 36  TRP E CE3 1 
ATOM 5063 C CZ2 . TRP D 4 36  ? 85.375  133.218 83.467  1.00 35.85  ? 36  TRP E CZ2 1 
ATOM 5064 C CZ3 . TRP D 4 36  ? 85.865  134.548 81.518  1.00 48.09  ? 36  TRP E CZ3 1 
ATOM 5065 C CH2 . TRP D 4 36  ? 84.987  133.778 82.285  1.00 46.49  ? 36  TRP E CH2 1 
ATOM 5066 N N   . VAL D 4 37  ? 91.565  135.396 80.407  1.00 45.20  ? 37  VAL E N   1 
ATOM 5067 C CA  . VAL D 4 37  ? 92.334  136.351 79.623  1.00 38.40  ? 37  VAL E CA  1 
ATOM 5068 C C   . VAL D 4 37  ? 91.356  137.361 79.050  1.00 43.02  ? 37  VAL E C   1 
ATOM 5069 O O   . VAL D 4 37  ? 90.328  136.979 78.483  1.00 55.55  ? 37  VAL E O   1 
ATOM 5070 C CB  . VAL D 4 37  ? 93.135  135.661 78.506  1.00 40.17  ? 37  VAL E CB  1 
ATOM 5071 C CG1 . VAL D 4 37  ? 93.910  136.682 77.699  1.00 45.05  ? 37  VAL E CG1 1 
ATOM 5072 C CG2 . VAL D 4 37  ? 94.076  134.628 79.100  1.00 36.41  ? 37  VAL E CG2 1 
ATOM 5073 N N   . ARG D 4 38  ? 91.665  138.642 79.202  1.00 47.58  ? 38  ARG E N   1 
ATOM 5074 C CA  . ARG D 4 38  ? 90.812  139.693 78.677  1.00 45.18  ? 38  ARG E CA  1 
ATOM 5075 C C   . ARG D 4 38  ? 91.519  140.445 77.563  1.00 53.27  ? 38  ARG E C   1 
ATOM 5076 O O   . ARG D 4 38  ? 92.743  140.402 77.427  1.00 56.42  ? 38  ARG E O   1 
ATOM 5077 C CB  . ARG D 4 38  ? 90.383  140.673 79.774  1.00 53.18  ? 38  ARG E CB  1 
ATOM 5078 C CG  . ARG D 4 38  ? 91.498  141.516 80.357  1.00 52.27  ? 38  ARG E CG  1 
ATOM 5079 C CD  . ARG D 4 38  ? 90.948  142.827 80.888  1.00 57.46  ? 38  ARG E CD  1 
ATOM 5080 N NE  . ARG D 4 38  ? 91.859  143.498 81.805  1.00 55.45  ? 38  ARG E NE  1 
ATOM 5081 C CZ  . ARG D 4 38  ? 91.643  143.632 83.106  1.00 54.57  ? 38  ARG E CZ  1 
ATOM 5082 N NH1 . ARG D 4 38  ? 90.543  143.168 83.674  1.00 57.70  ? 38  ARG E NH1 1 
ATOM 5083 N NH2 . ARG D 4 38  ? 92.549  144.254 83.854  1.00 57.95  ? 38  ARG E NH2 1 
ATOM 5084 N N   . GLN D 4 39  ? 90.718  141.134 76.757  1.00 66.72  ? 39  GLN E N   1 
ATOM 5085 C CA  . GLN D 4 39  ? 91.220  141.902 75.625  1.00 62.70  ? 39  GLN E CA  1 
ATOM 5086 C C   . GLN D 4 39  ? 90.457  143.215 75.579  1.00 66.81  ? 39  GLN E C   1 
ATOM 5087 O O   . GLN D 4 39  ? 89.261  143.230 75.275  1.00 68.11  ? 39  GLN E O   1 
ATOM 5088 C CB  . GLN D 4 39  ? 91.052  141.128 74.319  1.00 65.09  ? 39  GLN E CB  1 
ATOM 5089 C CG  . GLN D 4 39  ? 91.656  141.805 73.107  1.00 63.70  ? 39  GLN E CG  1 
ATOM 5090 C CD  . GLN D 4 39  ? 91.410  141.030 71.832  1.00 62.90  ? 39  GLN E CD  1 
ATOM 5091 O OE1 . GLN D 4 39  ? 90.335  140.469 71.632  1.00 65.81  ? 39  GLN E OE1 1 
ATOM 5092 N NE2 . GLN D 4 39  ? 92.412  140.986 70.966  1.00 64.95  ? 39  GLN E NE2 1 
ATOM 5093 N N   . ALA D 4 40  ? 91.146  144.311 75.878  1.00 81.27  ? 40  ALA E N   1 
ATOM 5094 C CA  . ALA D 4 40  ? 90.524  145.619 75.808  1.00 83.01  ? 40  ALA E CA  1 
ATOM 5095 C C   . ALA D 4 40  ? 90.186  145.953 74.357  1.00 83.21  ? 40  ALA E C   1 
ATOM 5096 O O   . ALA D 4 40  ? 90.865  145.494 73.436  1.00 83.16  ? 40  ALA E O   1 
ATOM 5097 C CB  . ALA D 4 40  ? 91.447  146.684 76.392  1.00 78.56  ? 40  ALA E CB  1 
ATOM 5098 N N   . PRO D 4 41  ? 89.126  146.724 74.126  1.00 89.50  ? 41  PRO E N   1 
ATOM 5099 C CA  . PRO D 4 41  ? 88.753  147.066 72.747  1.00 89.80  ? 41  PRO E CA  1 
ATOM 5100 C C   . PRO D 4 41  ? 89.904  147.738 72.013  1.00 90.33  ? 41  PRO E C   1 
ATOM 5101 O O   . PRO D 4 41  ? 90.522  148.677 72.519  1.00 90.03  ? 41  PRO E O   1 
ATOM 5102 C CB  . PRO D 4 41  ? 87.565  148.016 72.928  1.00 86.94  ? 41  PRO E CB  1 
ATOM 5103 C CG  . PRO D 4 41  ? 86.993  147.646 74.251  1.00 87.60  ? 41  PRO E CG  1 
ATOM 5104 C CD  . PRO D 4 41  ? 88.164  147.259 75.105  1.00 86.18  ? 41  PRO E CD  1 
ATOM 5105 N N   . GLU D 4 42  ? 90.185  147.242 70.806  1.00 88.70  ? 42  GLU E N   1 
ATOM 5106 C CA  . GLU D 4 42  ? 91.300  147.720 69.987  1.00 90.82  ? 42  GLU E CA  1 
ATOM 5107 C C   . GLU D 4 42  ? 92.628  147.637 70.740  1.00 94.21  ? 42  GLU E C   1 
ATOM 5108 O O   . GLU D 4 42  ? 93.486  148.514 70.619  1.00 93.93  ? 42  GLU E O   1 
ATOM 5109 C CB  . GLU D 4 42  ? 91.046  149.145 69.490  1.00 92.09  ? 42  GLU E CB  1 
ATOM 5110 C CG  . GLU D 4 42  ? 89.707  149.332 68.792  1.00 92.00  ? 42  GLU E CG  1 
ATOM 5111 C CD  . GLU D 4 42  ? 89.616  148.578 67.479  1.00 95.99  ? 42  GLU E CD  1 
ATOM 5112 O OE1 . GLU D 4 42  ? 90.674  148.294 66.878  1.00 95.22  ? 42  GLU E OE1 1 
ATOM 5113 O OE2 . GLU D 4 42  ? 88.486  148.270 67.048  1.00 95.04  ? 42  GLU E OE2 1 
ATOM 5114 N N   . LYS D 4 43  ? 92.802  146.572 71.522  1.00 85.93  ? 43  LYS E N   1 
ATOM 5115 C CA  . LYS D 4 43  ? 94.032  146.338 72.268  1.00 81.85  ? 43  LYS E CA  1 
ATOM 5116 C C   . LYS D 4 43  ? 94.371  144.854 72.211  1.00 81.60  ? 43  LYS E C   1 
ATOM 5117 O O   . LYS D 4 43  ? 93.639  144.049 71.629  1.00 80.74  ? 43  LYS E O   1 
ATOM 5118 C CB  . LYS D 4 43  ? 93.906  146.814 73.720  1.00 81.01  ? 43  LYS E CB  1 
ATOM 5119 C CG  . LYS D 4 43  ? 93.734  148.314 73.884  1.00 81.78  ? 43  LYS E CG  1 
ATOM 5120 C CD  . LYS D 4 43  ? 94.977  149.065 73.445  1.00 84.34  ? 43  LYS E CD  1 
ATOM 5121 C CE  . LYS D 4 43  ? 94.799  150.565 73.607  1.00 84.37  ? 43  LYS E CE  1 
ATOM 5122 N NZ  . LYS D 4 43  ? 93.642  151.072 72.820  1.00 83.64  ? 43  LYS E NZ  1 
ATOM 5123 N N   . GLY D 4 44  ? 95.498  144.494 72.823  1.00 69.78  ? 44  GLY E N   1 
ATOM 5124 C CA  . GLY D 4 44  ? 95.971  143.127 72.838  1.00 65.17  ? 44  GLY E CA  1 
ATOM 5125 C C   . GLY D 4 44  ? 95.417  142.324 73.999  1.00 69.50  ? 44  GLY E C   1 
ATOM 5126 O O   . GLY D 4 44  ? 94.574  142.780 74.773  1.00 73.74  ? 44  GLY E O   1 
ATOM 5127 N N   . LEU D 4 45  ? 95.915  141.096 74.115  1.00 61.85  ? 45  LEU E N   1 
ATOM 5128 C CA  . LEU D 4 45  ? 95.455  140.174 75.142  1.00 56.95  ? 45  LEU E CA  1 
ATOM 5129 C C   . LEU D 4 45  ? 96.132  140.478 76.473  1.00 59.28  ? 45  LEU E C   1 
ATOM 5130 O O   . LEU D 4 45  ? 97.285  140.912 76.523  1.00 62.52  ? 45  LEU E O   1 
ATOM 5131 C CB  . LEU D 4 45  ? 95.744  138.732 74.727  1.00 55.09  ? 45  LEU E CB  1 
ATOM 5132 C CG  . LEU D 4 45  ? 95.208  138.268 73.372  1.00 46.39  ? 45  LEU E CG  1 
ATOM 5133 C CD1 . LEU D 4 45  ? 95.790  136.916 73.011  1.00 50.60  ? 45  LEU E CD1 1 
ATOM 5134 C CD2 . LEU D 4 45  ? 93.694  138.202 73.387  1.00 52.78  ? 45  LEU E CD2 1 
ATOM 5135 N N   . GLU D 4 46  ? 95.397  140.254 77.561  1.00 59.97  ? 46  GLU E N   1 
ATOM 5136 C CA  . GLU D 4 46  ? 95.911  140.491 78.906  1.00 57.53  ? 46  GLU E CA  1 
ATOM 5137 C C   . GLU D 4 46  ? 95.455  139.375 79.831  1.00 59.85  ? 46  GLU E C   1 
ATOM 5138 O O   . GLU D 4 46  ? 94.251  139.154 79.990  1.00 64.88  ? 46  GLU E O   1 
ATOM 5139 C CB  . GLU D 4 46  ? 95.449  141.846 79.442  1.00 57.23  ? 46  GLU E CB  1 
ATOM 5140 C CG  . GLU D 4 46  ? 95.954  142.153 80.836  1.00 56.92  ? 46  GLU E CG  1 
ATOM 5141 C CD  . GLU D 4 46  ? 95.507  143.511 81.327  1.00 65.03  ? 46  GLU E CD  1 
ATOM 5142 O OE1 . GLU D 4 46  ? 94.761  144.193 80.595  1.00 63.33  ? 46  GLU E OE1 1 
ATOM 5143 O OE2 . GLU D 4 46  ? 95.902  143.898 82.446  1.00 66.04  ? 46  GLU E OE2 1 
ATOM 5144 N N   . TRP D 4 47  ? 96.408  138.682 80.443  1.00 44.85  ? 47  TRP E N   1 
ATOM 5145 C CA  . TRP D 4 47  ? 96.076  137.592 81.347  1.00 43.83  ? 47  TRP E CA  1 
ATOM 5146 C C   . TRP D 4 47  ? 95.528  138.147 82.658  1.00 43.98  ? 47  TRP E C   1 
ATOM 5147 O O   . TRP D 4 47  ? 96.059  139.115 83.208  1.00 60.61  ? 47  TRP E O   1 
ATOM 5148 C CB  . TRP D 4 47  ? 97.319  136.740 81.592  1.00 34.14  ? 47  TRP E CB  1 
ATOM 5149 C CG  . TRP D 4 47  ? 97.165  135.709 82.643  1.00 34.41  ? 47  TRP E CG  1 
ATOM 5150 C CD1 . TRP D 4 47  ? 96.599  134.480 82.507  1.00 38.22  ? 47  TRP E CD1 1 
ATOM 5151 C CD2 . TRP D 4 47  ? 97.594  135.807 84.002  1.00 34.00  ? 47  TRP E CD2 1 
ATOM 5152 N NE1 . TRP D 4 47  ? 96.644  133.806 83.699  1.00 37.20  ? 47  TRP E NE1 1 
ATOM 5153 C CE2 . TRP D 4 47  ? 97.252  134.601 84.634  1.00 37.99  ? 47  TRP E CE2 1 
ATOM 5154 C CE3 . TRP D 4 47  ? 98.236  136.799 84.745  1.00 38.42  ? 47  TRP E CE3 1 
ATOM 5155 C CZ2 . TRP D 4 47  ? 97.524  134.361 85.973  1.00 41.40  ? 47  TRP E CZ2 1 
ATOM 5156 C CZ3 . TRP D 4 47  ? 98.504  136.559 86.071  1.00 40.07  ? 47  TRP E CZ3 1 
ATOM 5157 C CH2 . TRP D 4 47  ? 98.151  135.350 86.673  1.00 41.81  ? 47  TRP E CH2 1 
ATOM 5158 N N   . VAL D 4 48  ? 94.461  137.529 83.164  1.00 29.75  ? 48  VAL E N   1 
ATOM 5159 C CA  . VAL D 4 48  ? 93.742  138.022 84.341  1.00 31.77  ? 48  VAL E CA  1 
ATOM 5160 C C   . VAL D 4 48  ? 93.991  137.146 85.567  1.00 29.32  ? 48  VAL E C   1 
ATOM 5161 O O   . VAL D 4 48  ? 94.458  137.628 86.598  1.00 48.61  ? 48  VAL E O   1 
ATOM 5162 C CB  . VAL D 4 48  ? 92.231  138.158 84.051  1.00 41.18  ? 48  VAL E CB  1 
ATOM 5163 C CG1 . VAL D 4 48  ? 91.475  138.506 85.317  1.00 37.07  ? 48  VAL E CG1 1 
ATOM 5164 C CG2 . VAL D 4 48  ? 91.998  139.209 82.996  1.00 40.95  ? 48  VAL E CG2 1 
ATOM 5165 N N   . ALA D 4 49  ? 93.677  135.858 85.476  1.00 26.39  ? 49  ALA E N   1 
ATOM 5166 C CA  . ALA D 4 49  ? 93.721  134.992 86.645  1.00 25.60  ? 49  ALA E CA  1 
ATOM 5167 C C   . ALA D 4 49  ? 93.929  133.558 86.190  1.00 33.74  ? 49  ALA E C   1 
ATOM 5168 O O   . ALA D 4 49  ? 93.771  133.229 85.015  1.00 44.09  ? 49  ALA E O   1 
ATOM 5169 C CB  . ALA D 4 49  ? 92.447  135.120 87.481  1.00 33.87  ? 49  ALA E CB  1 
ATOM 5170 N N   . TYR D 4 50  ? 94.287  132.705 87.146  1.00 34.80  ? 50  TYR E N   1 
ATOM 5171 C CA  . TYR D 4 50  ? 94.492  131.288 86.883  1.00 30.83  ? 50  TYR E CA  1 
ATOM 5172 C C   . TYR D 4 50  ? 94.065  130.474 88.094  1.00 36.47  ? 50  TYR E C   1 
ATOM 5173 O O   . TYR D 4 50  ? 94.400  130.832 89.224  1.00 48.89  ? 50  TYR E O   1 
ATOM 5174 C CB  . TYR D 4 50  ? 95.961  131.021 86.555  1.00 30.89  ? 50  TYR E CB  1 
ATOM 5175 C CG  . TYR D 4 50  ? 96.390  129.581 86.666  1.00 32.94  ? 50  TYR E CG  1 
ATOM 5176 C CD1 . TYR D 4 50  ? 95.901  128.623 85.795  1.00 38.43  ? 50  TYR E CD1 1 
ATOM 5177 C CD2 . TYR D 4 50  ? 97.310  129.186 87.624  1.00 29.04  ? 50  TYR E CD2 1 
ATOM 5178 C CE1 . TYR D 4 50  ? 96.300  127.313 85.883  1.00 38.84  ? 50  TYR E CE1 1 
ATOM 5179 C CE2 . TYR D 4 50  ? 97.714  127.877 87.719  1.00 35.94  ? 50  TYR E CE2 1 
ATOM 5180 C CZ  . TYR D 4 50  ? 97.206  126.944 86.845  1.00 41.15  ? 50  TYR E CZ  1 
ATOM 5181 O OH  . TYR D 4 50  ? 97.608  125.633 86.935  1.00 38.27  ? 50  TYR E OH  1 
ATOM 5182 N N   . ILE D 4 51  ? 93.327  129.391 87.863  1.00 32.57  ? 51  ILE E N   1 
ATOM 5183 C CA  . ILE D 4 51  ? 93.054  128.402 88.899  1.00 26.77  ? 51  ILE E CA  1 
ATOM 5184 C C   . ILE D 4 51  ? 93.444  127.031 88.365  1.00 32.00  ? 51  ILE E C   1 
ATOM 5185 O O   . ILE D 4 51  ? 93.072  126.664 87.246  1.00 49.90  ? 51  ILE E O   1 
ATOM 5186 C CB  . ILE D 4 51  ? 91.581  128.427 89.353  1.00 38.46  ? 51  ILE E CB  1 
ATOM 5187 C CG1 . ILE D 4 51  ? 91.342  127.392 90.452  1.00 40.72  ? 51  ILE E CG1 1 
ATOM 5188 C CG2 . ILE D 4 51  ? 90.633  128.212 88.186  1.00 37.94  ? 51  ILE E CG2 1 
ATOM 5189 C CD1 . ILE D 4 51  ? 89.979  127.488 91.078  1.00 43.99  ? 51  ILE E CD1 1 
ATOM 5190 N N   . SER D 4 52  ? 94.212  126.285 89.151  1.00 26.82  ? 52  SER E N   1 
ATOM 5191 C CA  . SER D 4 52  ? 94.734  125.008 88.696  1.00 34.46  ? 52  SER E CA  1 
ATOM 5192 C C   . SER D 4 52  ? 93.681  123.913 88.833  1.00 47.82  ? 52  SER E C   1 
ATOM 5193 O O   . SER D 4 52  ? 92.633  124.090 89.457  1.00 55.73  ? 52  SER E O   1 
ATOM 5194 C CB  . SER D 4 52  ? 95.994  124.635 89.473  1.00 37.53  ? 52  SER E CB  1 
ATOM 5195 O OG  . SER D 4 52  ? 95.719  124.490 90.851  1.00 39.34  ? 52  SER E OG  1 
ATOM 5196 N N   . SER D 4 53  ? 93.970  122.765 88.224  1.00 43.39  ? 53  SER E N   1 
ATOM 5197 C CA  . SER D 4 53  ? 93.161  121.577 88.457  1.00 40.13  ? 53  SER E CA  1 
ATOM 5198 C C   . SER D 4 53  ? 93.244  121.162 89.920  1.00 49.70  ? 53  SER E C   1 
ATOM 5199 O O   . SER D 4 53  ? 94.335  121.029 90.481  1.00 49.25  ? 53  SER E O   1 
ATOM 5200 C CB  . SER D 4 53  ? 93.626  120.437 87.557  1.00 43.97  ? 53  SER E CB  1 
ATOM 5201 O OG  . SER D 4 53  ? 92.812  119.293 87.735  1.00 52.54  ? 53  SER E OG  1 
ATOM 5202 N N   . GLY D 4 54  ? 92.087  120.934 90.530  1.00 47.33  ? 54  GLY E N   1 
ATOM 5203 C CA  . GLY D 4 54  ? 92.020  120.672 91.948  1.00 42.80  ? 54  GLY E CA  1 
ATOM 5204 C C   . GLY D 4 54  ? 91.992  121.905 92.822  1.00 45.22  ? 54  GLY E C   1 
ATOM 5205 O O   . GLY D 4 54  ? 91.974  121.767 94.051  1.00 56.32  ? 54  GLY E O   1 
ATOM 5206 N N   . SER D 4 55  ? 92.008  123.100 92.231  1.00 33.16  ? 55  SER E N   1 
ATOM 5207 C CA  . SER D 4 55  ? 91.831  124.367 92.935  1.00 37.90  ? 55  SER E CA  1 
ATOM 5208 C C   . SER D 4 55  ? 92.937  124.643 93.947  1.00 43.33  ? 55  SER E C   1 
ATOM 5209 O O   . SER D 4 55  ? 92.774  125.493 94.826  1.00 47.74  ? 55  SER E O   1 
ATOM 5210 C CB  . SER D 4 55  ? 90.464  124.426 93.625  1.00 43.91  ? 55  SER E CB  1 
ATOM 5211 O OG  . SER D 4 55  ? 89.416  124.222 92.696  1.00 43.09  ? 55  SER E OG  1 
ATOM 5212 N N   . GLY D 4 56  ? 94.071  123.947 93.846  1.00 42.60  ? 56  GLY E N   1 
ATOM 5213 C CA  . GLY D 4 56  ? 95.117  124.120 94.836  1.00 34.58  ? 56  GLY E CA  1 
ATOM 5214 C C   . GLY D 4 56  ? 95.955  125.363 94.643  1.00 36.40  ? 56  GLY E C   1 
ATOM 5215 O O   . GLY D 4 56  ? 96.473  125.917 95.616  1.00 41.39  ? 56  GLY E O   1 
ATOM 5216 N N   . THR D 4 57  ? 96.100  125.821 93.405  1.00 41.98  ? 57  THR E N   1 
ATOM 5217 C CA  . THR D 4 57  ? 96.929  126.971 93.078  1.00 39.59  ? 57  THR E CA  1 
ATOM 5218 C C   . THR D 4 57  ? 96.077  128.009 92.367  1.00 36.23  ? 57  THR E C   1 
ATOM 5219 O O   . THR D 4 57  ? 95.341  127.676 91.433  1.00 50.83  ? 57  THR E O   1 
ATOM 5220 C CB  . THR D 4 57  ? 98.116  126.570 92.199  1.00 41.67  ? 57  THR E CB  1 
ATOM 5221 O OG1 . THR D 4 57  ? 98.924  125.613 92.894  1.00 39.24  ? 57  THR E OG1 1 
ATOM 5222 C CG2 . THR D 4 57  ? 98.960  127.782 91.864  1.00 40.15  ? 57  THR E CG2 1 
ATOM 5223 N N   . ILE D 4 58  ? 96.167  129.257 92.815  1.00 27.34  ? 58  ILE E N   1 
ATOM 5224 C CA  . ILE D 4 58  ? 95.419  130.360 92.224  1.00 29.29  ? 58  ILE E CA  1 
ATOM 5225 C C   . ILE D 4 58  ? 96.365  131.539 92.059  1.00 34.50  ? 58  ILE E C   1 
ATOM 5226 O O   . ILE D 4 58  ? 97.079  131.904 92.998  1.00 39.85  ? 58  ILE E O   1 
ATOM 5227 C CB  . ILE D 4 58  ? 94.199  130.756 93.079  1.00 37.74  ? 58  ILE E CB  1 
ATOM 5228 C CG1 . ILE D 4 58  ? 93.234  129.581 93.215  1.00 41.07  ? 58  ILE E CG1 1 
ATOM 5229 C CG2 . ILE D 4 58  ? 93.479  131.932 92.462  1.00 33.10  ? 58  ILE E CG2 1 
ATOM 5230 C CD1 . ILE D 4 58  ? 92.010  129.897 94.038  1.00 39.03  ? 58  ILE E CD1 1 
ATOM 5231 N N   . TYR D 4 59  ? 96.375  132.131 90.869  1.00 37.67  ? 59  TYR E N   1 
ATOM 5232 C CA  . TYR D 4 59  ? 97.197  133.293 90.572  1.00 34.34  ? 59  TYR E CA  1 
ATOM 5233 C C   . TYR D 4 59  ? 96.327  134.395 89.989  1.00 40.68  ? 59  TYR E C   1 
ATOM 5234 O O   . TYR D 4 59  ? 95.330  134.129 89.316  1.00 46.01  ? 59  TYR E O   1 
ATOM 5235 C CB  . TYR D 4 59  ? 98.322  132.954 89.589  1.00 26.68  ? 59  TYR E CB  1 
ATOM 5236 C CG  . TYR D 4 59  ? 99.376  132.029 90.144  1.00 36.35  ? 59  TYR E CG  1 
ATOM 5237 C CD1 . TYR D 4 59  ? 99.798  132.135 91.458  1.00 44.06  ? 59  TYR E CD1 1 
ATOM 5238 C CD2 . TYR D 4 59  ? 99.946  131.046 89.356  1.00 43.49  ? 59  TYR E CD2 1 
ATOM 5239 C CE1 . TYR D 4 59  ? 100.759 131.290 91.968  1.00 47.90  ? 59  TYR E CE1 1 
ATOM 5240 C CE2 . TYR D 4 59  ? 100.908 130.196 89.857  1.00 39.21  ? 59  TYR E CE2 1 
ATOM 5241 C CZ  . TYR D 4 59  ? 101.310 130.323 91.162  1.00 49.94  ? 59  TYR E CZ  1 
ATOM 5242 O OH  . TYR D 4 59  ? 102.269 129.477 91.665  1.00 49.12  ? 59  TYR E OH  1 
ATOM 5243 N N   . TYR D 4 60  ? 96.714  135.638 90.262  1.00 39.97  ? 60  TYR E N   1 
ATOM 5244 C CA  . TYR D 4 60  ? 96.020  136.813 89.759  1.00 38.02  ? 60  TYR E CA  1 
ATOM 5245 C C   . TYR D 4 60  ? 97.027  137.786 89.168  1.00 39.39  ? 60  TYR E C   1 
ATOM 5246 O O   . TYR D 4 60  ? 98.192  137.818 89.570  1.00 47.20  ? 60  TYR E O   1 
ATOM 5247 C CB  . TYR D 4 60  ? 95.224  137.525 90.854  1.00 37.21  ? 60  TYR E CB  1 
ATOM 5248 C CG  . TYR D 4 60  ? 94.088  136.723 91.430  1.00 36.59  ? 60  TYR E CG  1 
ATOM 5249 C CD1 . TYR D 4 60  ? 92.861  136.660 90.789  1.00 35.84  ? 60  TYR E CD1 1 
ATOM 5250 C CD2 . TYR D 4 60  ? 94.240  136.030 92.619  1.00 43.11  ? 60  TYR E CD2 1 
ATOM 5251 C CE1 . TYR D 4 60  ? 91.822  135.929 91.315  1.00 38.92  ? 60  TYR E CE1 1 
ATOM 5252 C CE2 . TYR D 4 60  ? 93.205  135.299 93.152  1.00 44.41  ? 60  TYR E CE2 1 
ATOM 5253 C CZ  . TYR D 4 60  ? 92.000  135.251 92.497  1.00 43.03  ? 60  TYR E CZ  1 
ATOM 5254 O OH  . TYR D 4 60  ? 90.967  134.520 93.031  1.00 42.52  ? 60  TYR E OH  1 
ATOM 5255 N N   . ALA D 4 61  ? 96.564  138.583 88.212  1.00 39.55  ? 61  ALA E N   1 
ATOM 5256 C CA  . ALA D 4 61  ? 97.361  139.702 87.741  1.00 43.11  ? 61  ALA E CA  1 
ATOM 5257 C C   . ALA D 4 61  ? 97.370  140.809 88.788  1.00 52.15  ? 61  ALA E C   1 
ATOM 5258 O O   . ALA D 4 61  ? 96.420  140.975 89.556  1.00 59.05  ? 61  ALA E O   1 
ATOM 5259 C CB  . ALA D 4 61  ? 96.814  140.231 86.419  1.00 36.30  ? 61  ALA E CB  1 
ATOM 5260 N N   . ASP D 4 62  ? 98.467  141.568 88.818  1.00 58.41  ? 62  ASP E N   1 
ATOM 5261 C CA  . ASP D 4 62  ? 98.606  142.618 89.821  1.00 58.02  ? 62  ASP E CA  1 
ATOM 5262 C C   . ASP D 4 62  ? 97.547  143.697 89.657  1.00 60.15  ? 62  ASP E C   1 
ATOM 5263 O O   . ASP D 4 62  ? 97.082  144.265 90.651  1.00 63.26  ? 62  ASP E O   1 
ATOM 5264 C CB  . ASP D 4 62  ? 100.004 143.230 89.754  1.00 61.83  ? 62  ASP E CB  1 
ATOM 5265 C CG  . ASP D 4 62  ? 101.080 142.277 90.230  1.00 68.91  ? 62  ASP E CG  1 
ATOM 5266 O OD1 . ASP D 4 62  ? 100.730 141.182 90.719  1.00 67.12  ? 62  ASP E OD1 1 
ATOM 5267 O OD2 . ASP D 4 62  ? 102.276 142.620 90.116  1.00 67.22  ? 62  ASP E OD2 1 
ATOM 5268 N N   . THR D 4 63  ? 97.158  143.998 88.417  1.00 55.82  ? 63  THR E N   1 
ATOM 5269 C CA  . THR D 4 63  ? 96.179  145.051 88.179  1.00 56.83  ? 63  THR E CA  1 
ATOM 5270 C C   . THR D 4 63  ? 94.784  144.674 88.653  1.00 57.17  ? 63  THR E C   1 
ATOM 5271 O O   . THR D 4 63  ? 93.932  145.558 88.789  1.00 66.53  ? 63  THR E O   1 
ATOM 5272 C CB  . THR D 4 63  ? 96.130  145.401 86.692  1.00 60.82  ? 63  THR E CB  1 
ATOM 5273 O OG1 . THR D 4 63  ? 95.107  146.377 86.464  1.00 60.82  ? 63  THR E OG1 1 
ATOM 5274 C CG2 . THR D 4 63  ? 95.831  144.163 85.869  1.00 59.82  ? 63  THR E CG2 1 
ATOM 5275 N N   . VAL D 4 64  ? 94.529  143.395 88.912  1.00 54.53  ? 64  VAL E N   1 
ATOM 5276 C CA  . VAL D 4 64  ? 93.217  142.941 89.357  1.00 52.31  ? 64  VAL E CA  1 
ATOM 5277 C C   . VAL D 4 64  ? 93.262  142.211 90.688  1.00 57.97  ? 64  VAL E C   1 
ATOM 5278 O O   . VAL D 4 64  ? 92.197  141.859 91.216  1.00 69.49  ? 64  VAL E O   1 
ATOM 5279 C CB  . VAL D 4 64  ? 92.539  142.048 88.297  1.00 58.59  ? 64  VAL E CB  1 
ATOM 5280 C CG1 . VAL D 4 64  ? 92.410  142.789 86.978  1.00 59.68  ? 64  VAL E CG1 1 
ATOM 5281 C CG2 . VAL D 4 64  ? 93.315  140.757 88.118  1.00 52.27  ? 64  VAL E CG2 1 
ATOM 5282 N N   . LYS D 4 65  ? 94.445  141.958 91.243  1.00 64.32  ? 65  LYS E N   1 
ATOM 5283 C CA  . LYS D 4 65  ? 94.546  141.195 92.479  1.00 60.49  ? 65  LYS E CA  1 
ATOM 5284 C C   . LYS D 4 65  ? 93.887  141.946 93.626  1.00 61.99  ? 65  LYS E C   1 
ATOM 5285 O O   . LYS D 4 65  ? 94.090  143.152 93.795  1.00 63.37  ? 65  LYS E O   1 
ATOM 5286 C CB  . LYS D 4 65  ? 96.010  140.909 92.808  1.00 57.92  ? 65  LYS E CB  1 
ATOM 5287 C CG  . LYS D 4 65  ? 96.196  139.990 93.998  1.00 60.15  ? 65  LYS E CG  1 
ATOM 5288 C CD  . LYS D 4 65  ? 97.645  139.575 94.154  1.00 61.69  ? 65  LYS E CD  1 
ATOM 5289 C CE  . LYS D 4 65  ? 97.807  138.570 95.279  1.00 64.43  ? 65  LYS E CE  1 
ATOM 5290 N NZ  . LYS D 4 65  ? 99.229  138.169 95.458  1.00 66.61  ? 65  LYS E NZ  1 
ATOM 5291 N N   . GLY D 4 66  ? 93.094  141.225 94.416  1.00 64.81  ? 66  GLY E N   1 
ATOM 5292 C CA  . GLY D 4 66  ? 92.326  141.810 95.487  1.00 64.07  ? 66  GLY E CA  1 
ATOM 5293 C C   . GLY D 4 66  ? 90.914  142.205 95.118  1.00 65.04  ? 66  GLY E C   1 
ATOM 5294 O O   . GLY D 4 66  ? 90.063  142.305 96.007  1.00 65.91  ? 66  GLY E O   1 
ATOM 5295 N N   . ARG D 4 67  ? 90.635  142.427 93.835  1.00 64.71  ? 67  ARG E N   1 
ATOM 5296 C CA  . ARG D 4 67  ? 89.293  142.767 93.384  1.00 62.59  ? 67  ARG E CA  1 
ATOM 5297 C C   . ARG D 4 67  ? 88.588  141.631 92.667  1.00 67.95  ? 67  ARG E C   1 
ATOM 5298 O O   . ARG D 4 67  ? 87.365  141.521 92.767  1.00 69.88  ? 67  ARG E O   1 
ATOM 5299 C CB  . ARG D 4 67  ? 89.339  143.978 92.448  1.00 62.18  ? 67  ARG E CB  1 
ATOM 5300 C CG  . ARG D 4 67  ? 90.081  145.166 93.017  1.00 65.90  ? 67  ARG E CG  1 
ATOM 5301 C CD  . ARG D 4 67  ? 90.066  146.346 92.062  1.00 68.27  ? 67  ARG E CD  1 
ATOM 5302 N NE  . ARG D 4 67  ? 90.734  146.056 90.800  1.00 67.30  ? 67  ARG E NE  1 
ATOM 5303 C CZ  . ARG D 4 67  ? 90.107  145.773 89.667  1.00 66.15  ? 67  ARG E CZ  1 
ATOM 5304 N NH1 . ARG D 4 67  ? 88.787  145.735 89.599  1.00 70.11  ? 67  ARG E NH1 1 
ATOM 5305 N NH2 . ARG D 4 67  ? 90.822  145.529 88.573  1.00 64.62  ? 67  ARG E NH2 1 
ATOM 5306 N N   . PHE D 4 68  ? 89.324  140.785 91.956  1.00 64.98  ? 68  PHE E N   1 
ATOM 5307 C CA  . PHE D 4 68  ? 88.751  139.668 91.222  1.00 60.66  ? 68  PHE E CA  1 
ATOM 5308 C C   . PHE D 4 68  ? 88.991  138.377 91.990  1.00 63.70  ? 68  PHE E C   1 
ATOM 5309 O O   . PHE D 4 68  ? 90.041  138.200 92.613  1.00 67.12  ? 68  PHE E O   1 
ATOM 5310 C CB  . PHE D 4 68  ? 89.349  139.557 89.817  1.00 59.36  ? 68  PHE E CB  1 
ATOM 5311 C CG  . PHE D 4 68  ? 88.918  140.650 88.875  1.00 60.80  ? 68  PHE E CG  1 
ATOM 5312 C CD1 . PHE D 4 68  ? 88.102  141.679 89.302  1.00 64.88  ? 68  PHE E CD1 1 
ATOM 5313 C CD2 . PHE D 4 68  ? 89.327  140.636 87.556  1.00 66.15  ? 68  PHE E CD2 1 
ATOM 5314 C CE1 . PHE D 4 68  ? 87.715  142.677 88.435  1.00 66.62  ? 68  PHE E CE1 1 
ATOM 5315 C CE2 . PHE D 4 68  ? 88.938  141.629 86.686  1.00 64.19  ? 68  PHE E CE2 1 
ATOM 5316 C CZ  . PHE D 4 68  ? 88.131  142.649 87.126  1.00 64.80  ? 68  PHE E CZ  1 
ATOM 5317 N N   . THR D 4 69  ? 88.009  137.481 91.953  1.00 57.56  ? 69  THR E N   1 
ATOM 5318 C CA  . THR D 4 69  ? 88.144  136.155 92.537  1.00 63.22  ? 69  THR E CA  1 
ATOM 5319 C C   . THR D 4 69  ? 87.740  135.121 91.500  1.00 62.81  ? 69  THR E C   1 
ATOM 5320 O O   . THR D 4 69  ? 86.642  135.196 90.941  1.00 63.98  ? 69  THR E O   1 
ATOM 5321 C CB  . THR D 4 69  ? 87.287  136.003 93.797  1.00 64.08  ? 69  THR E CB  1 
ATOM 5322 O OG1 . THR D 4 69  ? 87.632  137.025 94.739  1.00 64.99  ? 69  THR E OG1 1 
ATOM 5323 C CG2 . THR D 4 69  ? 87.521  134.645 94.435  1.00 59.76  ? 69  THR E CG2 1 
ATOM 5324 N N   . ILE D 4 70  ? 88.620  134.157 91.253  1.00 55.86  ? 70  ILE E N   1 
ATOM 5325 C CA  . ILE D 4 70  ? 88.387  133.099 90.279  1.00 56.45  ? 70  ILE E CA  1 
ATOM 5326 C C   . ILE D 4 70  ? 88.122  131.809 91.039  1.00 62.00  ? 70  ILE E C   1 
ATOM 5327 O O   . ILE D 4 70  ? 88.816  131.498 92.015  1.00 62.16  ? 70  ILE E O   1 
ATOM 5328 C CB  . ILE D 4 70  ? 89.573  132.949 89.307  1.00 59.96  ? 70  ILE E CB  1 
ATOM 5329 C CG1 . ILE D 4 70  ? 89.310  131.841 88.288  1.00 55.71  ? 70  ILE E CG1 1 
ATOM 5330 C CG2 . ILE D 4 70  ? 90.866  132.666 90.048  1.00 46.95  ? 70  ILE E CG2 1 
ATOM 5331 C CD1 . ILE D 4 70  ? 90.420  131.674 87.285  1.00 55.09  ? 70  ILE E CD1 1 
ATOM 5332 N N   . SER D 4 71  ? 87.097  131.078 90.615  1.00 58.86  ? 71  SER E N   1 
ATOM 5333 C CA  . SER D 4 71  ? 86.728  129.834 91.266  1.00 56.70  ? 71  SER E CA  1 
ATOM 5334 C C   . SER D 4 71  ? 86.125  128.907 90.225  1.00 60.24  ? 71  SER E C   1 
ATOM 5335 O O   . SER D 4 71  ? 85.721  129.336 89.143  1.00 64.50  ? 71  SER E O   1 
ATOM 5336 C CB  . SER D 4 71  ? 85.747  130.070 92.419  1.00 58.02  ? 71  SER E CB  1 
ATOM 5337 O OG  . SER D 4 71  ? 84.569  130.710 91.963  1.00 56.05  ? 71  SER E OG  1 
ATOM 5338 N N   . ARG D 4 72  ? 86.063  127.625 90.568  1.00 51.50  ? 72  ARG E N   1 
ATOM 5339 C CA  . ARG D 4 72  ? 85.530  126.622 89.663  1.00 53.61  ? 72  ARG E CA  1 
ATOM 5340 C C   . ARG D 4 72  ? 84.623  125.680 90.436  1.00 55.21  ? 72  ARG E C   1 
ATOM 5341 O O   . ARG D 4 72  ? 84.782  125.486 91.643  1.00 57.82  ? 72  ARG E O   1 
ATOM 5342 C CB  . ARG D 4 72  ? 86.653  125.837 88.969  1.00 54.69  ? 72  ARG E CB  1 
ATOM 5343 C CG  . ARG D 4 72  ? 87.518  125.014 89.903  1.00 47.27  ? 72  ARG E CG  1 
ATOM 5344 C CD  . ARG D 4 72  ? 88.794  124.569 89.215  1.00 45.69  ? 72  ARG E CD  1 
ATOM 5345 N NE  . ARG D 4 72  ? 88.530  123.912 87.942  1.00 57.00  ? 72  ARG E NE  1 
ATOM 5346 C CZ  . ARG D 4 72  ? 89.470  123.520 87.093  1.00 50.78  ? 72  ARG E CZ  1 
ATOM 5347 N NH1 . ARG D 4 72  ? 90.752  123.706 87.350  1.00 49.16  ? 72  ARG E NH1 1 
ATOM 5348 N NH2 . ARG D 4 72  ? 89.113  122.933 85.956  1.00 46.23  ? 72  ARG E NH2 1 
ATOM 5349 N N   . ASP D 4 73  ? 83.665  125.099 89.722  1.00 64.69  ? 73  ASP E N   1 
ATOM 5350 C CA  . ASP D 4 73  ? 82.768  124.078 90.253  1.00 64.44  ? 73  ASP E CA  1 
ATOM 5351 C C   . ASP D 4 73  ? 82.926  122.849 89.366  1.00 66.68  ? 73  ASP E C   1 
ATOM 5352 O O   . ASP D 4 73  ? 82.281  122.740 88.321  1.00 73.12  ? 73  ASP E O   1 
ATOM 5353 C CB  . ASP D 4 73  ? 81.329  124.577 90.286  1.00 71.22  ? 73  ASP E CB  1 
ATOM 5354 C CG  . ASP D 4 73  ? 80.432  123.712 91.143  1.00 74.01  ? 73  ASP E CG  1 
ATOM 5355 O OD1 . ASP D 4 73  ? 80.929  122.721 91.717  1.00 73.95  ? 73  ASP E OD1 1 
ATOM 5356 O OD2 . ASP D 4 73  ? 79.229  124.025 91.247  1.00 71.25  ? 73  ASP E OD2 1 
ATOM 5357 N N   . ASP D 4 74  ? 83.793  121.928 89.785  1.00 53.36  ? 74  ASP E N   1 
ATOM 5358 C CA  . ASP D 4 74  ? 84.091  120.759 88.959  1.00 63.97  ? 74  ASP E CA  1 
ATOM 5359 C C   . ASP D 4 74  ? 82.864  119.901 88.672  1.00 67.37  ? 74  ASP E C   1 
ATOM 5360 O O   . ASP D 4 74  ? 82.695  119.483 87.513  1.00 64.72  ? 74  ASP E O   1 
ATOM 5361 C CB  . ASP D 4 74  ? 85.208  119.938 89.613  1.00 65.56  ? 74  ASP E CB  1 
ATOM 5362 C CG  . ASP D 4 74  ? 86.549  120.635 89.559  1.00 65.16  ? 74  ASP E CG  1 
ATOM 5363 O OD1 . ASP D 4 74  ? 86.622  121.739 88.982  1.00 63.88  ? 74  ASP E OD1 1 
ATOM 5364 O OD2 . ASP D 4 74  ? 87.532  120.078 90.089  1.00 60.23  ? 74  ASP E OD2 1 
ATOM 5365 N N   . PRO D 4 75  ? 81.996  119.579 89.640  1.00 70.02  ? 75  PRO E N   1 
ATOM 5366 C CA  . PRO D 4 75  ? 80.801  118.792 89.294  1.00 64.08  ? 75  PRO E CA  1 
ATOM 5367 C C   . PRO D 4 75  ? 79.906  119.451 88.260  1.00 67.49  ? 75  PRO E C   1 
ATOM 5368 O O   . PRO D 4 75  ? 79.306  118.745 87.441  1.00 68.67  ? 75  PRO E O   1 
ATOM 5369 C CB  . PRO D 4 75  ? 80.084  118.641 90.642  1.00 61.31  ? 75  PRO E CB  1 
ATOM 5370 C CG  . PRO D 4 75  ? 81.165  118.736 91.644  1.00 60.72  ? 75  PRO E CG  1 
ATOM 5371 C CD  . PRO D 4 75  ? 82.117  119.751 91.100  1.00 64.54  ? 75  PRO E CD  1 
ATOM 5372 N N   . LYS D 4 76  ? 79.790  120.776 88.268  1.00 61.71  ? 76  LYS E N   1 
ATOM 5373 C CA  . LYS D 4 76  ? 78.959  121.477 87.297  1.00 65.37  ? 76  LYS E CA  1 
ATOM 5374 C C   . LYS D 4 76  ? 79.717  121.903 86.046  1.00 67.20  ? 76  LYS E C   1 
ATOM 5375 O O   . LYS D 4 76  ? 79.092  122.421 85.115  1.00 64.75  ? 76  LYS E O   1 
ATOM 5376 C CB  . LYS D 4 76  ? 78.309  122.702 87.944  1.00 63.21  ? 76  LYS E CB  1 
ATOM 5377 C CG  . LYS D 4 76  ? 77.324  122.361 89.047  1.00 66.74  ? 76  LYS E CG  1 
ATOM 5378 C CD  . LYS D 4 76  ? 76.567  123.591 89.514  1.00 68.57  ? 76  LYS E CD  1 
ATOM 5379 C CE  . LYS D 4 76  ? 75.573  123.243 90.608  1.00 66.43  ? 76  LYS E CE  1 
ATOM 5380 N NZ  . LYS D 4 76  ? 74.828  124.442 91.080  1.00 67.49  ? 76  LYS E NZ  1 
ATOM 5381 N N   . ASN D 4 77  ? 81.034  121.693 85.999  1.00 63.08  ? 77  ASN E N   1 
ATOM 5382 C CA  . ASN D 4 77  ? 81.861  122.083 84.855  1.00 59.77  ? 77  ASN E CA  1 
ATOM 5383 C C   . ASN D 4 77  ? 81.713  123.567 84.531  1.00 62.54  ? 77  ASN E C   1 
ATOM 5384 O O   . ASN D 4 77  ? 81.574  123.956 83.370  1.00 68.05  ? 77  ASN E O   1 
ATOM 5385 C CB  . ASN D 4 77  ? 81.546  121.228 83.626  1.00 53.67  ? 77  ASN E CB  1 
ATOM 5386 C CG  . ASN D 4 77  ? 81.842  119.762 83.846  1.00 61.16  ? 77  ASN E CG  1 
ATOM 5387 O OD1 . ASN D 4 77  ? 82.781  119.406 84.555  1.00 64.94  ? 77  ASN E OD1 1 
ATOM 5388 N ND2 . ASN D 4 77  ? 81.037  118.900 83.240  1.00 59.98  ? 77  ASN E ND2 1 
ATOM 5389 N N   . THR D 4 78  ? 81.735  124.404 85.563  1.00 55.65  ? 78  THR E N   1 
ATOM 5390 C CA  . THR D 4 78  ? 81.589  125.844 85.411  1.00 59.14  ? 78  THR E CA  1 
ATOM 5391 C C   . THR D 4 78  ? 82.800  126.548 86.006  1.00 61.96  ? 78  THR E C   1 
ATOM 5392 O O   . THR D 4 78  ? 83.246  126.202 87.103  1.00 59.12  ? 78  THR E O   1 
ATOM 5393 C CB  . THR D 4 78  ? 80.305  126.346 86.077  1.00 65.13  ? 78  THR E CB  1 
ATOM 5394 O OG1 . THR D 4 78  ? 79.209  125.510 85.690  1.00 67.78  ? 78  THR E OG1 1 
ATOM 5395 C CG2 . THR D 4 78  ? 80.012  127.771 85.647  1.00 55.23  ? 78  THR E CG2 1 
ATOM 5396 N N   . LEU D 4 79  ? 83.330  127.526 85.278  1.00 57.48  ? 79  LEU E N   1 
ATOM 5397 C CA  . LEU D 4 79  ? 84.401  128.386 85.758  1.00 54.34  ? 79  LEU E CA  1 
ATOM 5398 C C   . LEU D 4 79  ? 83.835  129.764 86.065  1.00 58.57  ? 79  LEU E C   1 
ATOM 5399 O O   . LEU D 4 79  ? 83.047  130.308 85.286  1.00 57.58  ? 79  LEU E O   1 
ATOM 5400 C CB  . LEU D 4 79  ? 85.525  128.506 84.728  1.00 58.15  ? 79  LEU E CB  1 
ATOM 5401 C CG  . LEU D 4 79  ? 86.699  129.377 85.173  1.00 54.60  ? 79  LEU E CG  1 
ATOM 5402 C CD1 . LEU D 4 79  ? 87.512  128.659 86.235  1.00 51.61  ? 79  LEU E CD1 1 
ATOM 5403 C CD2 . LEU D 4 79  ? 87.566  129.780 83.997  1.00 57.15  ? 79  LEU E CD2 1 
ATOM 5404 N N   . PHE D 4 80  ? 84.250  130.335 87.192  1.00 62.19  ? 80  PHE E N   1 
ATOM 5405 C CA  . PHE D 4 80  ? 83.700  131.594 87.666  1.00 55.77  ? 80  PHE E CA  1 
ATOM 5406 C C   . PHE D 4 80  ? 84.778  132.663 87.746  1.00 60.29  ? 80  PHE E C   1 
ATOM 5407 O O   . PHE D 4 80  ? 85.965  132.367 87.911  1.00 64.21  ? 80  PHE E O   1 
ATOM 5408 C CB  . PHE D 4 80  ? 83.063  131.443 89.049  1.00 55.13  ? 80  PHE E CB  1 
ATOM 5409 C CG  . PHE D 4 80  ? 82.015  130.376 89.124  1.00 64.45  ? 80  PHE E CG  1 
ATOM 5410 C CD1 . PHE D 4 80  ? 80.759  130.580 88.586  1.00 60.73  ? 80  PHE E CD1 1 
ATOM 5411 C CD2 . PHE D 4 80  ? 82.277  129.179 89.762  1.00 61.79  ? 80  PHE E CD2 1 
ATOM 5412 C CE1 . PHE D 4 80  ? 79.795  129.603 88.663  1.00 60.11  ? 80  PHE E CE1 1 
ATOM 5413 C CE2 . PHE D 4 80  ? 81.317  128.199 89.843  1.00 60.67  ? 80  PHE E CE2 1 
ATOM 5414 C CZ  . PHE D 4 80  ? 80.074  128.411 89.293  1.00 63.07  ? 80  PHE E CZ  1 
ATOM 5415 N N   . LEU D 4 81  ? 84.346  133.915 87.617  1.00 63.07  ? 81  LEU E N   1 
ATOM 5416 C CA  . LEU D 4 81  ? 85.199  135.078 87.853  1.00 58.79  ? 81  LEU E CA  1 
ATOM 5417 C C   . LEU D 4 81  ? 84.334  136.106 88.571  1.00 59.76  ? 81  LEU E C   1 
ATOM 5418 O O   . LEU D 4 81  ? 83.495  136.761 87.947  1.00 64.83  ? 81  LEU E O   1 
ATOM 5419 C CB  . LEU D 4 81  ? 85.773  135.640 86.559  1.00 63.77  ? 81  LEU E CB  1 
ATOM 5420 C CG  . LEU D 4 81  ? 86.670  136.871 86.703  1.00 54.17  ? 81  LEU E CG  1 
ATOM 5421 C CD1 . LEU D 4 81  ? 87.920  136.530 87.497  1.00 55.85  ? 81  LEU E CD1 1 
ATOM 5422 C CD2 . LEU D 4 81  ? 87.031  137.438 85.347  1.00 54.67  ? 81  LEU E CD2 1 
ATOM 5423 N N   . GLN D 4 82  ? 84.532  136.238 89.876  1.00 66.27  ? 82  GLN E N   1 
ATOM 5424 C CA  . GLN D 4 82  ? 83.809  137.222 90.668  1.00 67.32  ? 82  GLN E CA  1 
ATOM 5425 C C   . GLN D 4 82  ? 84.580  138.532 90.624  1.00 69.48  ? 82  GLN E C   1 
ATOM 5426 O O   . GLN D 4 82  ? 85.741  138.586 91.039  1.00 75.26  ? 82  GLN E O   1 
ATOM 5427 C CB  . GLN D 4 82  ? 83.632  136.744 92.107  1.00 65.88  ? 82  GLN E CB  1 
ATOM 5428 C CG  . GLN D 4 82  ? 83.021  137.781 93.030  1.00 66.58  ? 82  GLN E CG  1 
ATOM 5429 C CD  . GLN D 4 82  ? 81.622  138.182 92.615  1.00 67.93  ? 82  GLN E CD  1 
ATOM 5430 O OE1 . GLN D 4 82  ? 80.860  137.369 92.096  1.00 69.36  ? 82  GLN E OE1 1 
ATOM 5431 N NE2 . GLN D 4 82  ? 81.277  139.443 92.840  1.00 68.33  ? 82  GLN E NE2 1 
ATOM 5432 N N   . MET D 4 83  ? 83.940  139.582 90.126  1.00 68.18  ? 83  MET E N   1 
ATOM 5433 C CA  . MET D 4 83  ? 84.582  140.875 89.969  1.00 70.50  ? 83  MET E CA  1 
ATOM 5434 C C   . MET D 4 83  ? 83.927  141.895 90.887  1.00 74.75  ? 83  MET E C   1 
ATOM 5435 O O   . MET D 4 83  ? 82.701  141.925 91.027  1.00 77.16  ? 83  MET E O   1 
ATOM 5436 C CB  . MET D 4 83  ? 84.502  141.342 88.515  1.00 72.34  ? 83  MET E CB  1 
ATOM 5437 C CG  . MET D 4 83  ? 85.131  140.373 87.523  1.00 74.14  ? 83  MET E CG  1 
ATOM 5438 S SD  . MET D 4 83  ? 85.041  140.943 85.818  1.00 77.33  ? 83  MET E SD  1 
ATOM 5439 C CE  . MET D 4 83  ? 83.272  141.006 85.592  1.00 76.98  ? 83  MET E CE  1 
ATOM 5440 N N   . THR D 4 84  ? 84.755  142.732 91.508  1.00 83.28  ? 84  THR E N   1 
ATOM 5441 C CA  . THR D 4 84  ? 84.293  143.773 92.412  1.00 79.82  ? 84  THR E CA  1 
ATOM 5442 C C   . THR D 4 84  ? 85.067  145.051 92.134  1.00 76.72  ? 84  THR E C   1 
ATOM 5443 O O   . THR D 4 84  ? 86.193  145.021 91.632  1.00 80.45  ? 84  THR E O   1 
ATOM 5444 C CB  . THR D 4 84  ? 84.461  143.372 93.884  1.00 79.33  ? 84  THR E CB  1 
ATOM 5445 O OG1 . THR D 4 84  ? 85.815  142.974 94.121  1.00 82.69  ? 84  THR E OG1 1 
ATOM 5446 C CG2 . THR D 4 84  ? 83.531  142.224 94.240  1.00 76.24  ? 84  THR E CG2 1 
ATOM 5447 N N   . SER D 4 85  ? 84.448  146.180 92.481  1.00 82.37  ? 85  SER E N   1 
ATOM 5448 C CA  . SER D 4 85  ? 85.057  147.501 92.321  1.00 84.81  ? 85  SER E CA  1 
ATOM 5449 C C   . SER D 4 85  ? 85.489  147.733 90.875  1.00 85.34  ? 85  SER E C   1 
ATOM 5450 O O   . SER D 4 85  ? 86.605  148.175 90.597  1.00 84.88  ? 85  SER E O   1 
ATOM 5451 C CB  . SER D 4 85  ? 86.235  147.683 93.281  1.00 81.83  ? 85  SER E CB  1 
ATOM 5452 O OG  . SER D 4 85  ? 85.822  147.552 94.629  1.00 83.83  ? 85  SER E OG  1 
ATOM 5453 N N   . LEU D 4 86  ? 84.587  147.418 89.948  1.00 83.30  ? 86  LEU E N   1 
ATOM 5454 C CA  . LEU D 4 86  ? 84.915  147.487 88.531  1.00 83.82  ? 86  LEU E CA  1 
ATOM 5455 C C   . LEU D 4 86  ? 85.219  148.919 88.115  1.00 82.90  ? 86  LEU E C   1 
ATOM 5456 O O   . LEU D 4 86  ? 84.500  149.853 88.480  1.00 86.85  ? 86  LEU E O   1 
ATOM 5457 C CB  . LEU D 4 86  ? 83.770  146.919 87.695  1.00 80.94  ? 86  LEU E CB  1 
ATOM 5458 C CG  . LEU D 4 86  ? 83.620  145.399 87.771  1.00 84.39  ? 86  LEU E CG  1 
ATOM 5459 C CD1 . LEU D 4 86  ? 82.457  144.923 86.925  1.00 84.43  ? 86  LEU E CD1 1 
ATOM 5460 C CD2 . LEU D 4 86  ? 84.907  144.725 87.335  1.00 80.64  ? 86  LEU E CD2 1 
ATOM 5461 N N   . ARG D 4 87  ? 86.295  149.086 87.357  1.00 83.97  ? 87  ARG E N   1 
ATOM 5462 C CA  . ARG D 4 87  ? 86.748  150.380 86.877  1.00 83.78  ? 87  ARG E CA  1 
ATOM 5463 C C   . ARG D 4 87  ? 86.550  150.465 85.370  1.00 85.93  ? 87  ARG E C   1 
ATOM 5464 O O   . ARG D 4 87  ? 86.259  149.472 84.701  1.00 91.39  ? 87  ARG E O   1 
ATOM 5465 C CB  . ARG D 4 87  ? 88.223  150.603 87.228  1.00 83.90  ? 87  ARG E CB  1 
ATOM 5466 C CG  . ARG D 4 87  ? 88.606  150.166 88.629  1.00 87.33  ? 87  ARG E CG  1 
ATOM 5467 C CD  . ARG D 4 87  ? 90.113  150.185 88.810  1.00 84.77  ? 87  ARG E CD  1 
ATOM 5468 N NE  . ARG D 4 87  ? 90.513  149.687 90.120  1.00 87.07  ? 87  ARG E NE  1 
ATOM 5469 C CZ  . ARG D 4 87  ? 91.769  149.482 90.490  1.00 88.37  ? 87  ARG E CZ  1 
ATOM 5470 N NH1 . ARG D 4 87  ? 92.778  149.719 89.668  1.00 88.12  ? 87  ARG E NH1 1 
ATOM 5471 N NH2 . ARG D 4 87  ? 92.020  149.027 91.714  1.00 85.83  ? 87  ARG E NH2 1 
ATOM 5472 N N   . SER D 4 88  ? 86.710  151.676 84.835  1.00 92.52  ? 88  SER E N   1 
ATOM 5473 C CA  . SER D 4 88  ? 86.644  151.851 83.390  1.00 92.82  ? 88  SER E CA  1 
ATOM 5474 C C   . SER D 4 88  ? 87.781  151.129 82.681  1.00 91.26  ? 88  SER E C   1 
ATOM 5475 O O   . SER D 4 88  ? 87.680  150.861 81.479  1.00 89.58  ? 88  SER E O   1 
ATOM 5476 C CB  . SER D 4 88  ? 86.665  153.337 83.035  1.00 91.43  ? 88  SER E CB  1 
ATOM 5477 O OG  . SER D 4 88  ? 87.848  153.955 83.508  1.00 93.85  ? 88  SER E OG  1 
ATOM 5478 N N   . GLU D 4 89  ? 88.858  150.809 83.400  1.00 86.51  ? 89  GLU E N   1 
ATOM 5479 C CA  . GLU D 4 89  ? 89.969  150.044 82.853  1.00 85.83  ? 89  GLU E CA  1 
ATOM 5480 C C   . GLU D 4 89  ? 89.627  148.572 82.659  1.00 85.83  ? 89  GLU E C   1 
ATOM 5481 O O   . GLU D 4 89  ? 90.377  147.861 81.984  1.00 86.69  ? 89  GLU E O   1 
ATOM 5482 C CB  . GLU D 4 89  ? 91.185  150.193 83.773  1.00 84.02  ? 89  GLU E CB  1 
ATOM 5483 C CG  . GLU D 4 89  ? 92.515  149.757 83.176  1.00 87.05  ? 89  GLU E CG  1 
ATOM 5484 C CD  . GLU D 4 89  ? 92.886  148.338 83.554  1.00 90.79  ? 89  GLU E CD  1 
ATOM 5485 O OE1 . GLU D 4 89  ? 92.122  147.704 84.312  1.00 88.33  ? 89  GLU E OE1 1 
ATOM 5486 O OE2 . GLU D 4 89  ? 93.944  147.856 83.096  1.00 86.78  ? 89  GLU E OE2 1 
ATOM 5487 N N   . ASP D 4 90  ? 88.508  148.108 83.208  1.00 78.76  ? 90  ASP E N   1 
ATOM 5488 C CA  . ASP D 4 90  ? 88.112  146.710 83.116  1.00 76.60  ? 90  ASP E CA  1 
ATOM 5489 C C   . ASP D 4 90  ? 87.228  146.420 81.914  1.00 77.27  ? 90  ASP E C   1 
ATOM 5490 O O   . ASP D 4 90  ? 86.802  145.274 81.741  1.00 83.78  ? 90  ASP E O   1 
ATOM 5491 C CB  . ASP D 4 90  ? 87.393  146.282 84.397  1.00 77.67  ? 90  ASP E CB  1 
ATOM 5492 C CG  . ASP D 4 90  ? 88.289  146.346 85.615  1.00 84.02  ? 90  ASP E CG  1 
ATOM 5493 O OD1 . ASP D 4 90  ? 89.495  146.617 85.450  1.00 86.79  ? 90  ASP E OD1 1 
ATOM 5494 O OD2 . ASP D 4 90  ? 87.789  146.126 86.736  1.00 82.83  ? 90  ASP E OD2 1 
ATOM 5495 N N   . THR D 4 91  ? 86.938  147.420 81.087  1.00 77.92  ? 91  THR E N   1 
ATOM 5496 C CA  . THR D 4 91  ? 86.124  147.213 79.894  1.00 82.31  ? 91  THR E CA  1 
ATOM 5497 C C   . THR D 4 91  ? 86.914  146.383 78.892  1.00 81.86  ? 91  THR E C   1 
ATOM 5498 O O   . THR D 4 91  ? 87.872  146.876 78.289  1.00 83.24  ? 91  THR E O   1 
ATOM 5499 C CB  . THR D 4 91  ? 85.724  148.554 79.287  1.00 80.86  ? 91  THR E CB  1 
ATOM 5500 O OG1 . THR D 4 91  ? 84.951  149.299 80.235  1.00 83.97  ? 91  THR E OG1 1 
ATOM 5501 C CG2 . THR D 4 91  ? 84.904  148.341 78.026  1.00 79.96  ? 91  THR E CG2 1 
ATOM 5502 N N   . ALA D 4 92  ? 86.516  145.126 78.708  1.00 75.69  ? 92  ALA E N   1 
ATOM 5503 C CA  . ALA D 4 92  ? 87.236  144.230 77.814  1.00 74.77  ? 92  ALA E CA  1 
ATOM 5504 C C   . ALA D 4 92  ? 86.367  143.021 77.503  1.00 73.52  ? 92  ALA E C   1 
ATOM 5505 O O   . ALA D 4 92  ? 85.330  142.795 78.128  1.00 79.29  ? 92  ALA E O   1 
ATOM 5506 C CB  . ALA D 4 92  ? 88.569  143.793 78.424  1.00 73.09  ? 92  ALA E CB  1 
ATOM 5507 N N   . MET D 4 93  ? 86.814  142.243 76.520  1.00 69.52  ? 93  MET E N   1 
ATOM 5508 C CA  . MET D 4 93  ? 86.252  140.932 76.227  1.00 63.65  ? 93  MET E CA  1 
ATOM 5509 C C   . MET D 4 93  ? 87.020  139.880 77.015  1.00 65.18  ? 93  MET E C   1 
ATOM 5510 O O   . MET D 4 93  ? 88.238  139.754 76.859  1.00 73.13  ? 93  MET E O   1 
ATOM 5511 C CB  . MET D 4 93  ? 86.329  140.635 74.730  1.00 63.21  ? 93  MET E CB  1 
ATOM 5512 C CG  . MET D 4 93  ? 85.973  139.208 74.354  1.00 63.24  ? 93  MET E CG  1 
ATOM 5513 S SD  . MET D 4 93  ? 84.219  138.984 74.017  1.00 87.15  ? 93  MET E SD  1 
ATOM 5514 C CE  . MET D 4 93  ? 84.066  139.854 72.461  1.00 64.55  ? 93  MET E CE  1 
ATOM 5515 N N   . TYR D 4 94  ? 86.315  139.126 77.850  1.00 54.56  ? 94  TYR E N   1 
ATOM 5516 C CA  . TYR D 4 94  ? 86.937  138.163 78.747  1.00 53.99  ? 94  TYR E CA  1 
ATOM 5517 C C   . TYR D 4 94  ? 86.823  136.765 78.155  1.00 53.10  ? 94  TYR E C   1 
ATOM 5518 O O   . TYR D 4 94  ? 85.716  136.287 77.895  1.00 55.34  ? 94  TYR E O   1 
ATOM 5519 C CB  . TYR D 4 94  ? 86.291  138.217 80.130  1.00 57.22  ? 94  TYR E CB  1 
ATOM 5520 C CG  . TYR D 4 94  ? 86.670  139.442 80.924  1.00 55.29  ? 94  TYR E CG  1 
ATOM 5521 C CD1 . TYR D 4 94  ? 86.066  140.665 80.681  1.00 50.70  ? 94  TYR E CD1 1 
ATOM 5522 C CD2 . TYR D 4 94  ? 87.632  139.374 81.918  1.00 56.67  ? 94  TYR E CD2 1 
ATOM 5523 C CE1 . TYR D 4 94  ? 86.414  141.784 81.403  1.00 51.23  ? 94  TYR E CE1 1 
ATOM 5524 C CE2 . TYR D 4 94  ? 87.984  140.486 82.644  1.00 53.73  ? 94  TYR E CE2 1 
ATOM 5525 C CZ  . TYR D 4 94  ? 87.373  141.688 82.384  1.00 53.80  ? 94  TYR E CZ  1 
ATOM 5526 O OH  . TYR D 4 94  ? 87.723  142.800 83.109  1.00 58.54  ? 94  TYR E OH  1 
ATOM 5527 N N   . TYR D 4 95  ? 87.965  136.112 77.961  1.00 47.97  ? 95  TYR E N   1 
ATOM 5528 C CA  . TYR D 4 95  ? 88.030  134.795 77.348  1.00 44.26  ? 95  TYR E CA  1 
ATOM 5529 C C   . TYR D 4 95  ? 88.307  133.739 78.406  1.00 47.61  ? 95  TYR E C   1 
ATOM 5530 O O   . TYR D 4 95  ? 89.104  133.955 79.322  1.00 53.97  ? 95  TYR E O   1 
ATOM 5531 C CB  . TYR D 4 95  ? 89.114  134.731 76.275  1.00 44.59  ? 95  TYR E CB  1 
ATOM 5532 C CG  . TYR D 4 95  ? 88.846  135.586 75.062  1.00 49.56  ? 95  TYR E CG  1 
ATOM 5533 C CD1 . TYR D 4 95  ? 88.047  135.124 74.030  1.00 50.15  ? 95  TYR E CD1 1 
ATOM 5534 C CD2 . TYR D 4 95  ? 89.412  136.845 74.939  1.00 45.44  ? 95  TYR E CD2 1 
ATOM 5535 C CE1 . TYR D 4 95  ? 87.808  135.896 72.917  1.00 53.47  ? 95  TYR E CE1 1 
ATOM 5536 C CE2 . TYR D 4 95  ? 89.178  137.622 73.831  1.00 43.65  ? 95  TYR E CE2 1 
ATOM 5537 C CZ  . TYR D 4 95  ? 88.377  137.143 72.822  1.00 52.72  ? 95  TYR E CZ  1 
ATOM 5538 O OH  . TYR D 4 95  ? 88.141  137.919 71.713  1.00 56.67  ? 95  TYR E OH  1 
ATOM 5539 N N   . CYS D 4 96  ? 87.650  132.595 78.266  1.00 44.95  ? 96  CYS E N   1 
ATOM 5540 C CA  . CYS D 4 96  ? 87.870  131.436 79.118  1.00 39.53  ? 96  CYS E CA  1 
ATOM 5541 C C   . CYS D 4 96  ? 88.821  130.495 78.395  1.00 53.46  ? 96  CYS E C   1 
ATOM 5542 O O   . CYS D 4 96  ? 88.535  130.064 77.273  1.00 62.77  ? 96  CYS E O   1 
ATOM 5543 C CB  . CYS D 4 96  ? 86.541  130.749 79.424  1.00 51.71  ? 96  CYS E CB  1 
ATOM 5544 S SG  . CYS D 4 96  ? 86.568  129.405 80.608  1.00 69.92  ? 96  CYS E SG  1 
ATOM 5545 N N   . VAL D 4 97  ? 89.950  130.185 79.025  1.00 39.72  ? 97  VAL E N   1 
ATOM 5546 C CA  . VAL D 4 97  ? 91.010  129.404 78.400  1.00 31.75  ? 97  VAL E CA  1 
ATOM 5547 C C   . VAL D 4 97  ? 91.292  128.187 79.266  1.00 36.26  ? 97  VAL E C   1 
ATOM 5548 O O   . VAL D 4 97  ? 91.509  128.317 80.475  1.00 48.29  ? 97  VAL E O   1 
ATOM 5549 C CB  . VAL D 4 97  ? 92.294  130.230 78.213  1.00 29.15  ? 97  VAL E CB  1 
ATOM 5550 C CG1 . VAL D 4 97  ? 93.278  129.481 77.333  1.00 26.26  ? 97  VAL E CG1 1 
ATOM 5551 C CG2 . VAL D 4 97  ? 91.981  131.597 77.648  1.00 29.57  ? 97  VAL E CG2 1 
ATOM 5552 N N   . ARG D 4 98  ? 91.287  127.011 78.650  1.00 38.41  ? 98  ARG E N   1 
ATOM 5553 C CA  . ARG D 4 98  ? 91.697  125.789 79.320  1.00 37.42  ? 98  ARG E CA  1 
ATOM 5554 C C   . ARG D 4 98  ? 93.176  125.530 79.061  1.00 35.00  ? 98  ARG E C   1 
ATOM 5555 O O   . ARG D 4 98  ? 93.714  125.888 78.012  1.00 51.14  ? 98  ARG E O   1 
ATOM 5556 C CB  . ARG D 4 98  ? 90.865  124.598 78.846  1.00 42.23  ? 98  ARG E CB  1 
ATOM 5557 C CG  . ARG D 4 98  ? 91.180  124.143 77.442  1.00 37.29  ? 98  ARG E CG  1 
ATOM 5558 C CD  . ARG D 4 98  ? 90.545  122.808 77.130  1.00 38.67  ? 98  ARG E CD  1 
ATOM 5559 N NE  . ARG D 4 98  ? 91.141  122.202 75.947  1.00 44.69  ? 98  ARG E NE  1 
ATOM 5560 C CZ  . ARG D 4 98  ? 90.812  121.013 75.465  1.00 45.60  ? 98  ARG E CZ  1 
ATOM 5561 N NH1 . ARG D 4 98  ? 89.883  120.268 76.037  1.00 49.05  ? 98  ARG E NH1 1 
ATOM 5562 N NH2 . ARG D 4 98  ? 91.433  120.559 74.381  1.00 48.77  ? 98  ARG E NH2 1 
ATOM 5563 N N   . SER D 4 99  ? 93.840  124.925 80.041  1.00 28.19  ? 99  SER E N   1 
ATOM 5564 C CA  . SER D 4 99  ? 95.254  124.597 79.888  1.00 34.87  ? 99  SER E CA  1 
ATOM 5565 C C   . SER D 4 99  ? 95.589  123.449 80.821  1.00 34.83  ? 99  SER E C   1 
ATOM 5566 O O   . SER D 4 99  ? 95.362  123.549 82.029  1.00 42.85  ? 99  SER E O   1 
ATOM 5567 C CB  . SER D 4 99  ? 96.136  125.807 80.177  1.00 39.20  ? 99  SER E CB  1 
ATOM 5568 O OG  . SER D 4 99  ? 96.069  126.177 81.539  1.00 55.73  ? 99  SER E OG  1 
ATOM 5569 N N   . ILE D 4 100 ? 96.115  122.363 80.268  1.00 34.39  ? 100 ILE E N   1 
ATOM 5570 C CA  . ILE D 4 100 ? 96.521  121.197 81.039  1.00 37.42  ? 100 ILE E CA  1 
ATOM 5571 C C   . ILE D 4 100 ? 98.039  121.114 81.003  1.00 34.77  ? 100 ILE E C   1 
ATOM 5572 O O   . ILE D 4 100 ? 98.664  121.429 79.984  1.00 27.72  ? 100 ILE E O   1 
ATOM 5573 C CB  . ILE D 4 100 ? 95.857  119.914 80.496  1.00 34.76  ? 100 ILE E CB  1 
ATOM 5574 C CG1 . ILE D 4 100 ? 96.126  118.726 81.415  1.00 32.84  ? 100 ILE E CG1 1 
ATOM 5575 C CG2 . ILE D 4 100 ? 96.300  119.625 79.072  1.00 34.12  ? 100 ILE E CG2 1 
ATOM 5576 C CD1 . ILE D 4 100 ? 95.251  117.543 81.125  1.00 34.86  ? 100 ILE E CD1 1 
ATOM 5577 N N   . TYR D 4 101 ? 98.636  120.700 82.118  1.00 30.85  ? 101 TYR E N   1 
ATOM 5578 C CA  . TYR D 4 101 ? 100.085 120.742 82.281  1.00 22.25  ? 101 TYR E CA  1 
ATOM 5579 C C   . TYR D 4 101 ? 100.600 119.366 82.664  1.00 26.45  ? 101 TYR E C   1 
ATOM 5580 O O   . TYR D 4 101 ? 100.392 118.909 83.791  1.00 42.74  ? 101 TYR E O   1 
ATOM 5581 C CB  . TYR D 4 101 ? 100.493 121.772 83.329  1.00 29.41  ? 101 TYR E CB  1 
ATOM 5582 C CG  . TYR D 4 101 ? 100.025 123.172 83.033  1.00 29.48  ? 101 TYR E CG  1 
ATOM 5583 C CD1 . TYR D 4 101 ? 100.778 124.023 82.242  1.00 36.39  ? 101 TYR E CD1 1 
ATOM 5584 C CD2 . TYR D 4 101 ? 98.831  123.643 83.545  1.00 31.38  ? 101 TYR E CD2 1 
ATOM 5585 C CE1 . TYR D 4 101 ? 100.351 125.300 81.969  1.00 32.18  ? 101 TYR E CE1 1 
ATOM 5586 C CE2 . TYR D 4 101 ? 98.397  124.917 83.277  1.00 28.57  ? 101 TYR E CE2 1 
ATOM 5587 C CZ  . TYR D 4 101 ? 99.159  125.741 82.489  1.00 30.85  ? 101 TYR E CZ  1 
ATOM 5588 O OH  . TYR D 4 101 ? 98.720  127.015 82.227  1.00 43.22  ? 101 TYR E OH  1 
ATOM 5589 N N   . TYR D 4 102 ? 101.269 118.716 81.721  1.00 32.29  ? 102 TYR E N   1 
ATOM 5590 C CA  . TYR D 4 102 ? 102.090 117.548 81.982  1.00 30.14  ? 102 TYR E CA  1 
ATOM 5591 C C   . TYR D 4 102 ? 103.165 117.527 80.909  1.00 35.84  ? 102 TYR E C   1 
ATOM 5592 O O   . TYR D 4 102 ? 103.163 118.354 79.995  1.00 42.88  ? 102 TYR E O   1 
ATOM 5593 C CB  . TYR D 4 102 ? 101.263 116.259 82.005  1.00 35.84  ? 102 TYR E CB  1 
ATOM 5594 C CG  . TYR D 4 102 ? 100.379 116.059 80.797  1.00 31.01  ? 102 TYR E CG  1 
ATOM 5595 C CD1 . TYR D 4 102 ? 100.863 115.450 79.651  1.00 29.36  ? 102 TYR E CD1 1 
ATOM 5596 C CD2 . TYR D 4 102 ? 99.059  116.473 80.807  1.00 25.72  ? 102 TYR E CD2 1 
ATOM 5597 C CE1 . TYR D 4 102 ? 100.064 115.266 78.552  1.00 30.31  ? 102 TYR E CE1 1 
ATOM 5598 C CE2 . TYR D 4 102 ? 98.253  116.290 79.713  1.00 36.01  ? 102 TYR E CE2 1 
ATOM 5599 C CZ  . TYR D 4 102 ? 98.760  115.686 78.588  1.00 43.08  ? 102 TYR E CZ  1 
ATOM 5600 O OH  . TYR D 4 102 ? 97.958  115.503 77.489  1.00 41.81  ? 102 TYR E OH  1 
ATOM 5601 N N   . TYR D 4 103 ? 104.099 116.593 81.033  1.00 30.76  ? 103 TYR E N   1 
ATOM 5602 C CA  . TYR D 4 103 ? 105.190 116.521 80.070  1.00 37.19  ? 103 TYR E CA  1 
ATOM 5603 C C   . TYR D 4 103 ? 104.654 116.309 78.661  1.00 44.30  ? 103 TYR E C   1 
ATOM 5604 O O   . TYR D 4 103 ? 103.993 115.304 78.382  1.00 52.55  ? 103 TYR E O   1 
ATOM 5605 C CB  . TYR D 4 103 ? 106.158 115.403 80.438  1.00 26.96  ? 103 TYR E CB  1 
ATOM 5606 C CG  . TYR D 4 103 ? 107.206 115.176 79.382  1.00 28.79  ? 103 TYR E CG  1 
ATOM 5607 C CD1 . TYR D 4 103 ? 108.269 116.049 79.237  1.00 37.89  ? 103 TYR E CD1 1 
ATOM 5608 C CD2 . TYR D 4 103 ? 107.128 114.095 78.523  1.00 41.36  ? 103 TYR E CD2 1 
ATOM 5609 C CE1 . TYR D 4 103 ? 109.226 115.849 78.266  1.00 42.14  ? 103 TYR E CE1 1 
ATOM 5610 C CE2 . TYR D 4 103 ? 108.081 113.886 77.551  1.00 42.41  ? 103 TYR E CE2 1 
ATOM 5611 C CZ  . TYR D 4 103 ? 109.128 114.765 77.427  1.00 41.03  ? 103 TYR E CZ  1 
ATOM 5612 O OH  . TYR D 4 103 ? 110.082 114.559 76.459  1.00 43.75  ? 103 TYR E OH  1 
ATOM 5613 N N   . GLY D 4 104 ? 104.947 117.256 77.773  1.00 34.74  ? 104 GLY E N   1 
ATOM 5614 C CA  . GLY D 4 104 ? 104.522 117.179 76.396  1.00 29.85  ? 104 GLY E CA  1 
ATOM 5615 C C   . GLY D 4 104 ? 103.132 117.700 76.118  1.00 33.64  ? 104 GLY E C   1 
ATOM 5616 O O   . GLY D 4 104 ? 102.674 117.608 74.974  1.00 36.58  ? 104 GLY E O   1 
ATOM 5617 N N   . SER D 4 105 ? 102.448 118.245 77.117  1.00 36.69  ? 105 SER E N   1 
ATOM 5618 C CA  . SER D 4 105 ? 101.119 118.791 76.911  1.00 36.54  ? 105 SER E CA  1 
ATOM 5619 C C   . SER D 4 105 ? 101.195 120.113 76.149  1.00 49.29  ? 105 SER E C   1 
ATOM 5620 O O   . SER D 4 105 ? 102.262 120.705 75.970  1.00 54.43  ? 105 SER E O   1 
ATOM 5621 C CB  . SER D 4 105 ? 100.406 118.986 78.245  1.00 30.71  ? 105 SER E CB  1 
ATOM 5622 O OG  . SER D 4 105 ? 101.162 119.820 79.102  1.00 44.05  ? 105 SER E OG  1 
ATOM 5623 N N   . SER D 4 106 ? 100.032 120.574 75.694  1.00 57.34  ? 106 SER E N   1 
ATOM 5624 C CA  . SER D 4 106 ? 99.900  121.831 74.962  1.00 52.60  ? 106 SER E CA  1 
ATOM 5625 C C   . SER D 4 106 ? 98.956  122.748 75.726  1.00 51.11  ? 106 SER E C   1 
ATOM 5626 O O   . SER D 4 106 ? 97.738  122.733 75.495  1.00 52.05  ? 106 SER E O   1 
ATOM 5627 C CB  . SER D 4 106 ? 99.397  121.589 73.543  1.00 51.17  ? 106 SER E CB  1 
ATOM 5628 O OG  . SER D 4 106 ? 98.153  120.922 73.563  1.00 57.54  ? 106 SER E OG  1 
ATOM 5629 N N   . PRO D 4 107 ? 99.469  123.543 76.659  1.00 46.80  ? 107 PRO E N   1 
ATOM 5630 C CA  . PRO D 4 107 ? 98.615  124.490 77.380  1.00 45.66  ? 107 PRO E CA  1 
ATOM 5631 C C   . PRO D 4 107 ? 98.080  125.574 76.460  1.00 45.25  ? 107 PRO E C   1 
ATOM 5632 O O   . PRO D 4 107 ? 98.630  125.853 75.393  1.00 57.43  ? 107 PRO E O   1 
ATOM 5633 C CB  . PRO D 4 107 ? 99.552  125.078 78.440  1.00 39.32  ? 107 PRO E CB  1 
ATOM 5634 C CG  . PRO D 4 107 ? 100.632 124.068 78.588  1.00 42.87  ? 107 PRO E CG  1 
ATOM 5635 C CD  . PRO D 4 107 ? 100.822 123.480 77.231  1.00 45.29  ? 107 PRO E CD  1 
ATOM 5636 N N   . PHE D 4 108 ? 96.965  126.169 76.886  1.00 35.45  ? 108 PHE E N   1 
ATOM 5637 C CA  . PHE D 4 108 ? 96.319  127.265 76.165  1.00 36.15  ? 108 PHE E CA  1 
ATOM 5638 C C   . PHE D 4 108 ? 95.832  126.825 74.790  1.00 42.28  ? 108 PHE E C   1 
ATOM 5639 O O   . PHE D 4 108 ? 95.746  127.632 73.864  1.00 51.33  ? 108 PHE E O   1 
ATOM 5640 C CB  . PHE D 4 108 ? 97.247  128.478 76.041  1.00 37.26  ? 108 PHE E CB  1 
ATOM 5641 C CG  . PHE D 4 108 ? 97.362  129.280 77.302  1.00 45.83  ? 108 PHE E CG  1 
ATOM 5642 C CD1 . PHE D 4 108 ? 98.169  128.855 78.338  1.00 50.00  ? 108 PHE E CD1 1 
ATOM 5643 C CD2 . PHE D 4 108 ? 96.657  130.460 77.451  1.00 45.13  ? 108 PHE E CD2 1 
ATOM 5644 C CE1 . PHE D 4 108 ? 98.269  129.589 79.494  1.00 44.25  ? 108 PHE E CE1 1 
ATOM 5645 C CE2 . PHE D 4 108 ? 96.755  131.198 78.607  1.00 39.17  ? 108 PHE E CE2 1 
ATOM 5646 C CZ  . PHE D 4 108 ? 97.560  130.761 79.627  1.00 40.49  ? 108 PHE E CZ  1 
ATOM 5647 N N   . ASP D 4 109 ? 95.500  125.541 74.651  1.00 39.53  ? 109 ASP E N   1 
ATOM 5648 C CA  . ASP D 4 109 ? 95.131  125.009 73.346  1.00 38.68  ? 109 ASP E CA  1 
ATOM 5649 C C   . ASP D 4 109 ? 93.723  125.405 72.927  1.00 43.62  ? 109 ASP E C   1 
ATOM 5650 O O   . ASP D 4 109 ? 93.471  125.580 71.730  1.00 45.50  ? 109 ASP E O   1 
ATOM 5651 C CB  . ASP D 4 109 ? 95.280  123.487 73.333  1.00 32.46  ? 109 ASP E CB  1 
ATOM 5652 C CG  . ASP D 4 109 ? 94.467  122.812 74.408  1.00 49.67  ? 109 ASP E CG  1 
ATOM 5653 O OD1 . ASP D 4 109 ? 94.188  123.458 75.438  1.00 55.74  ? 109 ASP E OD1 1 
ATOM 5654 O OD2 . ASP D 4 109 ? 94.112  121.630 74.226  1.00 49.34  ? 109 ASP E OD2 1 
ATOM 5655 N N   . PHE D 4 110 ? 92.796  125.552 73.869  1.00 39.74  ? 110 PHE E N   1 
ATOM 5656 C CA  . PHE D 4 110 ? 91.419  125.900 73.546  1.00 41.22  ? 110 PHE E CA  1 
ATOM 5657 C C   . PHE D 4 110 ? 90.995  127.147 74.307  1.00 38.93  ? 110 PHE E C   1 
ATOM 5658 O O   . PHE D 4 110 ? 91.211  127.245 75.518  1.00 48.72  ? 110 PHE E O   1 
ATOM 5659 C CB  . PHE D 4 110 ? 90.469  124.741 73.846  1.00 40.73  ? 110 PHE E CB  1 
ATOM 5660 C CG  . PHE D 4 110 ? 89.114  124.909 73.232  1.00 46.06  ? 110 PHE E CG  1 
ATOM 5661 C CD1 . PHE D 4 110 ? 88.944  124.790 71.866  1.00 44.31  ? 110 PHE E CD1 1 
ATOM 5662 C CD2 . PHE D 4 110 ? 88.012  125.190 74.015  1.00 46.67  ? 110 PHE E CD2 1 
ATOM 5663 C CE1 . PHE D 4 110 ? 87.704  124.950 71.295  1.00 42.70  ? 110 PHE E CE1 1 
ATOM 5664 C CE2 . PHE D 4 110 ? 86.769  125.349 73.448  1.00 45.20  ? 110 PHE E CE2 1 
ATOM 5665 C CZ  . PHE D 4 110 ? 86.616  125.229 72.087  1.00 42.12  ? 110 PHE E CZ  1 
ATOM 5666 N N   . TRP D 4 111 ? 90.386  128.088 73.590  1.00 35.39  ? 111 TRP E N   1 
ATOM 5667 C CA  . TRP D 4 111 ? 89.867  129.327 74.146  1.00 38.24  ? 111 TRP E CA  1 
ATOM 5668 C C   . TRP D 4 111 ? 88.357  129.373 73.969  1.00 38.48  ? 111 TRP E C   1 
ATOM 5669 O O   . TRP D 4 111 ? 87.811  128.797 73.026  1.00 48.59  ? 111 TRP E O   1 
ATOM 5670 C CB  . TRP D 4 111 ? 90.488  130.554 73.464  1.00 41.18  ? 111 TRP E CB  1 
ATOM 5671 C CG  . TRP D 4 111 ? 91.934  130.783 73.758  1.00 40.98  ? 111 TRP E CG  1 
ATOM 5672 C CD1 . TRP D 4 111 ? 92.951  129.885 73.637  1.00 35.48  ? 111 TRP E CD1 1 
ATOM 5673 C CD2 . TRP D 4 111 ? 92.531  132.008 74.192  1.00 37.13  ? 111 TRP E CD2 1 
ATOM 5674 N NE1 . TRP D 4 111 ? 94.142  130.469 73.982  1.00 37.35  ? 111 TRP E NE1 1 
ATOM 5675 C CE2 . TRP D 4 111 ? 93.911  131.774 74.328  1.00 40.08  ? 111 TRP E CE2 1 
ATOM 5676 C CE3 . TRP D 4 111 ? 92.031  133.278 74.487  1.00 34.38  ? 111 TRP E CE3 1 
ATOM 5677 C CZ2 . TRP D 4 111 ? 94.795  132.761 74.745  1.00 34.43  ? 111 TRP E CZ2 1 
ATOM 5678 C CZ3 . TRP D 4 111 ? 92.911  134.255 74.898  1.00 38.11  ? 111 TRP E CZ3 1 
ATOM 5679 C CH2 . TRP D 4 111 ? 94.277  133.992 75.022  1.00 35.58  ? 111 TRP E CH2 1 
ATOM 5680 N N   . GLY D 4 112 ? 87.685  130.069 74.880  1.00 46.00  ? 112 GLY E N   1 
ATOM 5681 C CA  . GLY D 4 112 ? 86.262  130.281 74.743  1.00 44.52  ? 112 GLY E CA  1 
ATOM 5682 C C   . GLY D 4 112 ? 85.924  131.412 73.791  1.00 49.83  ? 112 GLY E C   1 
ATOM 5683 O O   . GLY D 4 112 ? 86.787  132.147 73.315  1.00 58.24  ? 112 GLY E O   1 
ATOM 5684 N N   . GLN D 4 113 ? 84.627  131.543 73.504  1.00 57.46  ? 113 GLN E N   1 
ATOM 5685 C CA  . GLN D 4 113 ? 84.177  132.588 72.590  1.00 60.92  ? 113 GLN E CA  1 
ATOM 5686 C C   . GLN D 4 113 ? 84.249  133.968 73.228  1.00 63.54  ? 113 GLN E C   1 
ATOM 5687 O O   . GLN D 4 113 ? 84.357  134.972 72.516  1.00 58.96  ? 113 GLN E O   1 
ATOM 5688 C CB  . GLN D 4 113 ? 82.757  132.296 72.111  1.00 61.92  ? 113 GLN E CB  1 
ATOM 5689 C CG  . GLN D 4 113 ? 82.662  131.118 71.160  1.00 63.84  ? 113 GLN E CG  1 
ATOM 5690 C CD  . GLN D 4 113 ? 83.420  131.352 69.867  1.00 69.51  ? 113 GLN E CD  1 
ATOM 5691 O OE1 . GLN D 4 113 ? 84.011  130.431 69.305  1.00 70.11  ? 113 GLN E OE1 1 
ATOM 5692 N NE2 . GLN D 4 113 ? 83.400  132.589 69.385  1.00 67.75  ? 113 GLN E NE2 1 
ATOM 5693 N N   . GLY D 4 114 ? 84.178  134.040 74.544  1.00 62.19  ? 114 GLY E N   1 
ATOM 5694 C CA  . GLY D 4 114 ? 84.360  135.292 75.246  1.00 60.33  ? 114 GLY E CA  1 
ATOM 5695 C C   . GLY D 4 114 ? 83.045  135.980 75.554  1.00 62.25  ? 114 GLY E C   1 
ATOM 5696 O O   . GLY D 4 114 ? 82.032  135.790 74.873  1.00 64.60  ? 114 GLY E O   1 
ATOM 5697 N N   . THR D 4 115 ? 83.059  136.799 76.602  1.00 67.34  ? 115 THR E N   1 
ATOM 5698 C CA  . THR D 4 115 ? 81.926  137.631 76.977  1.00 65.20  ? 115 THR E CA  1 
ATOM 5699 C C   . THR D 4 115 ? 82.403  139.064 77.154  1.00 66.16  ? 115 THR E C   1 
ATOM 5700 O O   . THR D 4 115 ? 83.507  139.303 77.652  1.00 64.76  ? 115 THR E O   1 
ATOM 5701 C CB  . THR D 4 115 ? 81.254  137.126 78.263  1.00 71.51  ? 115 THR E CB  1 
ATOM 5702 O OG1 . THR D 4 115 ? 80.181  138.005 78.622  1.00 72.76  ? 115 THR E OG1 1 
ATOM 5703 C CG2 . THR D 4 115 ? 82.253  137.052 79.409  1.00 69.30  ? 115 THR E CG2 1 
ATOM 5704 N N   . THR D 4 116 ? 81.579  140.016 76.730  1.00 74.12  ? 116 THR E N   1 
ATOM 5705 C CA  . THR D 4 116 ? 81.958  141.422 76.708  1.00 74.79  ? 116 THR E CA  1 
ATOM 5706 C C   . THR D 4 116 ? 81.459  142.113 77.969  1.00 75.32  ? 116 THR E C   1 
ATOM 5707 O O   . THR D 4 116 ? 80.270  142.039 78.293  1.00 76.41  ? 116 THR E O   1 
ATOM 5708 C CB  . THR D 4 116 ? 81.393  142.123 75.471  1.00 75.76  ? 116 THR E CB  1 
ATOM 5709 O OG1 . THR D 4 116 ? 81.903  141.497 74.288  1.00 75.61  ? 116 THR E OG1 1 
ATOM 5710 C CG2 . THR D 4 116 ? 81.783  143.591 75.466  1.00 74.32  ? 116 THR E CG2 1 
ATOM 5711 N N   . LEU D 4 117 ? 82.367  142.786 78.669  1.00 77.20  ? 117 LEU E N   1 
ATOM 5712 C CA  . LEU D 4 117 ? 82.037  143.589 79.838  1.00 75.38  ? 117 LEU E CA  1 
ATOM 5713 C C   . LEU D 4 117 ? 82.349  145.045 79.533  1.00 79.91  ? 117 LEU E C   1 
ATOM 5714 O O   . LEU D 4 117 ? 83.469  145.370 79.126  1.00 81.28  ? 117 LEU E O   1 
ATOM 5715 C CB  . LEU D 4 117 ? 82.821  143.133 81.067  1.00 73.67  ? 117 LEU E CB  1 
ATOM 5716 C CG  . LEU D 4 117 ? 82.520  143.902 82.354  1.00 77.04  ? 117 LEU E CG  1 
ATOM 5717 C CD1 . LEU D 4 117 ? 81.205  143.448 82.959  1.00 81.24  ? 117 LEU E CD1 1 
ATOM 5718 C CD2 . LEU D 4 117 ? 83.653  143.760 83.350  1.00 77.43  ? 117 LEU E CD2 1 
ATOM 5719 N N   . THR D 4 118 ? 81.367  145.917 79.735  1.00 89.42  ? 118 THR E N   1 
ATOM 5720 C CA  . THR D 4 118 ? 81.526  147.346 79.508  1.00 91.62  ? 118 THR E CA  1 
ATOM 5721 C C   . THR D 4 118 ? 81.220  148.095 80.795  1.00 92.28  ? 118 THR E C   1 
ATOM 5722 O O   . THR D 4 118 ? 80.182  147.861 81.421  1.00 95.54  ? 118 THR E O   1 
ATOM 5723 C CB  . THR D 4 118 ? 80.611  147.833 78.383  1.00 89.69  ? 118 THR E CB  1 
ATOM 5724 O OG1 . THR D 4 118 ? 80.885  147.091 77.188  1.00 90.41  ? 118 THR E OG1 1 
ATOM 5725 C CG2 . THR D 4 118 ? 80.840  149.311 78.114  1.00 87.16  ? 118 THR E CG2 1 
ATOM 5726 N N   . VAL D 4 119 ? 82.126  148.983 81.192  1.00 93.69  ? 119 VAL E N   1 
ATOM 5727 C CA  . VAL D 4 119 ? 81.973  149.791 82.395  1.00 92.36  ? 119 VAL E CA  1 
ATOM 5728 C C   . VAL D 4 119 ? 81.779  151.239 81.971  1.00 94.93  ? 119 VAL E C   1 
ATOM 5729 O O   . VAL D 4 119 ? 82.563  151.770 81.175  1.00 96.58  ? 119 VAL E O   1 
ATOM 5730 C CB  . VAL D 4 119 ? 83.184  149.643 83.331  1.00 92.63  ? 119 VAL E CB  1 
ATOM 5731 C CG1 . VAL D 4 119 ? 82.972  150.449 84.597  1.00 94.98  ? 119 VAL E CG1 1 
ATOM 5732 C CG2 . VAL D 4 119 ? 83.418  148.182 83.661  1.00 92.32  ? 119 VAL E CG2 1 
ATOM 5733 N N   . SER D 4 120 ? 80.739  151.876 82.501  1.00 104.95 ? 120 SER E N   1 
ATOM 5734 C CA  . SER D 4 120 ? 80.405  153.247 82.128  1.00 103.75 ? 120 SER E CA  1 
ATOM 5735 C C   . SER D 4 120 ? 81.438  154.246 82.639  1.00 104.31 ? 120 SER E C   1 
ATOM 5736 O O   . SER D 4 120 ? 82.442  153.867 83.239  1.00 105.07 ? 120 SER E O   1 
ATOM 5737 C CB  . SER D 4 120 ? 79.020  153.621 82.656  1.00 103.97 ? 120 SER E CB  1 
ATOM 5738 O OG  . SER D 4 120 ? 78.021  152.779 82.109  1.00 103.73 ? 120 SER E OG  1 
ATOM 5739 N N   . ASP D 4 137 ? 107.930 141.497 85.947  1.00 54.10  ? 137 ASP E N   1 
ATOM 5740 C CA  . ASP D 4 137 ? 107.094 141.227 84.784  1.00 61.68  ? 137 ASP E CA  1 
ATOM 5741 C C   . ASP D 4 137 ? 107.923 141.166 83.511  1.00 58.77  ? 137 ASP E C   1 
ATOM 5742 O O   . ASP D 4 137 ? 108.583 142.134 83.144  1.00 61.82  ? 137 ASP E O   1 
ATOM 5743 C CB  . ASP D 4 137 ? 106.009 142.296 84.644  1.00 63.71  ? 137 ASP E CB  1 
ATOM 5744 C CG  . ASP D 4 137 ? 104.959 142.206 85.730  1.00 66.14  ? 137 ASP E CG  1 
ATOM 5745 O OD1 . ASP D 4 137 ? 105.331 142.195 86.921  1.00 64.45  ? 137 ASP E OD1 1 
ATOM 5746 O OD2 . ASP D 4 137 ? 103.758 142.157 85.393  1.00 63.23  ? 137 ASP E OD2 1 
ATOM 5747 N N   . ILE D 4 138 ? 107.887 140.016 82.840  1.00 59.42  ? 138 ILE E N   1 
ATOM 5748 C CA  . ILE D 4 138 ? 108.581 139.871 81.568  1.00 54.39  ? 138 ILE E CA  1 
ATOM 5749 C C   . ILE D 4 138 ? 107.839 140.662 80.502  1.00 50.11  ? 138 ILE E C   1 
ATOM 5750 O O   . ILE D 4 138 ? 106.618 140.536 80.350  1.00 58.03  ? 138 ILE E O   1 
ATOM 5751 C CB  . ILE D 4 138 ? 108.695 138.388 81.193  1.00 53.03  ? 138 ILE E CB  1 
ATOM 5752 C CG1 . ILE D 4 138 ? 109.384 137.622 82.321  1.00 52.75  ? 138 ILE E CG1 1 
ATOM 5753 C CG2 . ILE D 4 138 ? 109.455 138.223 79.893  1.00 54.10  ? 138 ILE E CG2 1 
ATOM 5754 C CD1 . ILE D 4 138 ? 109.537 136.153 82.057  1.00 56.82  ? 138 ILE E CD1 1 
ATOM 5755 N N   . VAL D 4 139 ? 108.571 141.479 79.755  1.00 50.34  ? 139 VAL E N   1 
ATOM 5756 C CA  . VAL D 4 139 ? 107.998 142.323 78.713  1.00 54.27  ? 139 VAL E CA  1 
ATOM 5757 C C   . VAL D 4 139 ? 108.160 141.623 77.372  1.00 54.20  ? 139 VAL E C   1 
ATOM 5758 O O   . VAL D 4 139 ? 109.282 141.321 76.952  1.00 59.95  ? 139 VAL E O   1 
ATOM 5759 C CB  . VAL D 4 139 ? 108.646 143.715 78.695  1.00 57.40  ? 139 VAL E CB  1 
ATOM 5760 C CG1 . VAL D 4 139 ? 108.049 144.556 77.585  1.00 56.80  ? 139 VAL E CG1 1 
ATOM 5761 C CG2 . VAL D 4 139 ? 108.459 144.399 80.035  1.00 51.06  ? 139 VAL E CG2 1 
ATOM 5762 N N   . MET D 4 140 ? 107.045 141.361 76.700  1.00 57.64  ? 140 MET E N   1 
ATOM 5763 C CA  . MET D 4 140 ? 107.050 140.771 75.368  1.00 55.14  ? 140 MET E CA  1 
ATOM 5764 C C   . MET D 4 140 ? 106.784 141.884 74.365  1.00 60.28  ? 140 MET E C   1 
ATOM 5765 O O   . MET D 4 140 ? 105.771 142.583 74.464  1.00 68.90  ? 140 MET E O   1 
ATOM 5766 C CB  . MET D 4 140 ? 105.999 139.669 75.250  1.00 56.79  ? 140 MET E CB  1 
ATOM 5767 C CG  . MET D 4 140 ? 106.048 138.640 76.363  1.00 52.73  ? 140 MET E CG  1 
ATOM 5768 S SD  . MET D 4 140 ? 107.638 137.811 76.473  1.00 70.51  ? 140 MET E SD  1 
ATOM 5769 C CE  . MET D 4 140 ? 107.674 136.974 74.897  1.00 61.27  ? 140 MET E CE  1 
ATOM 5770 N N   . THR D 4 141 ? 107.691 142.054 73.408  1.00 65.89  ? 141 THR E N   1 
ATOM 5771 C CA  . THR D 4 141 ? 107.650 143.176 72.481  1.00 67.15  ? 141 THR E CA  1 
ATOM 5772 C C   . THR D 4 141 ? 107.440 142.670 71.064  1.00 66.51  ? 141 THR E C   1 
ATOM 5773 O O   . THR D 4 141 ? 108.181 141.801 70.593  1.00 71.85  ? 141 THR E O   1 
ATOM 5774 C CB  . THR D 4 141 ? 108.937 144.002 72.556  1.00 67.53  ? 141 THR E CB  1 
ATOM 5775 O OG1 . THR D 4 141 ? 109.141 144.452 73.900  1.00 69.81  ? 141 THR E OG1 1 
ATOM 5776 C CG2 . THR D 4 141 ? 108.846 145.208 71.637  1.00 63.60  ? 141 THR E CG2 1 
ATOM 5777 N N   . GLN D 4 142 ? 106.434 143.219 70.391  1.00 71.53  ? 142 GLN E N   1 
ATOM 5778 C CA  . GLN D 4 142 ? 106.194 142.999 68.968  1.00 69.90  ? 142 GLN E CA  1 
ATOM 5779 C C   . GLN D 4 142 ? 106.170 144.380 68.322  1.00 75.51  ? 142 GLN E C   1 
ATOM 5780 O O   . GLN D 4 142 ? 105.106 144.985 68.168  1.00 77.36  ? 142 GLN E O   1 
ATOM 5781 C CB  . GLN D 4 142 ? 104.896 142.240 68.736  1.00 71.90  ? 142 GLN E CB  1 
ATOM 5782 C CG  . GLN D 4 142 ? 104.790 140.956 69.531  1.00 70.19  ? 142 GLN E CG  1 
ATOM 5783 C CD  . GLN D 4 142 ? 103.540 140.170 69.207  1.00 67.57  ? 142 GLN E CD  1 
ATOM 5784 O OE1 . GLN D 4 142 ? 102.875 139.647 70.098  1.00 69.30  ? 142 GLN E OE1 1 
ATOM 5785 N NE2 . GLN D 4 142 ? 103.213 140.079 67.926  1.00 70.97  ? 142 GLN E NE2 1 
ATOM 5786 N N   . ALA D 4 143 ? 107.354 144.875 67.952  1.00 90.82  ? 143 ALA E N   1 
ATOM 5787 C CA  . ALA D 4 143 ? 107.468 146.245 67.462  1.00 92.00  ? 143 ALA E CA  1 
ATOM 5788 C C   . ALA D 4 143 ? 106.678 146.444 66.176  1.00 95.23  ? 143 ALA E C   1 
ATOM 5789 O O   . ALA D 4 143 ? 106.020 147.475 65.997  1.00 93.45  ? 143 ALA E O   1 
ATOM 5790 C CB  . ALA D 4 143 ? 108.938 146.605 67.250  1.00 86.67  ? 143 ALA E CB  1 
ATOM 5791 N N   . THR D 4 144 ? 106.731 145.473 65.269  1.00 98.76  ? 144 THR E N   1 
ATOM 5792 C CA  . THR D 4 144 ? 106.005 145.577 64.009  1.00 99.44  ? 144 THR E CA  1 
ATOM 5793 C C   . THR D 4 144 ? 104.517 145.389 64.277  1.00 99.04  ? 144 THR E C   1 
ATOM 5794 O O   . THR D 4 144 ? 104.059 144.268 64.523  1.00 98.96  ? 144 THR E O   1 
ATOM 5795 C CB  . THR D 4 144 ? 106.519 144.544 63.013  1.00 100.87 ? 144 THR E CB  1 
ATOM 5796 O OG1 . THR D 4 144 ? 107.949 144.485 63.081  1.00 100.23 ? 144 THR E OG1 1 
ATOM 5797 C CG2 . THR D 4 144 ? 106.113 144.932 61.603  1.00 99.02  ? 144 THR E CG2 1 
ATOM 5798 N N   . SER D 4 145 ? 103.758 146.485 64.235  1.00 103.71 ? 145 SER E N   1 
ATOM 5799 C CA  . SER D 4 145 ? 102.328 146.401 64.513  1.00 102.94 ? 145 SER E CA  1 
ATOM 5800 C C   . SER D 4 145 ? 101.571 145.760 63.358  1.00 103.30 ? 145 SER E C   1 
ATOM 5801 O O   . SER D 4 145 ? 100.660 144.953 63.579  1.00 102.25 ? 145 SER E O   1 
ATOM 5802 C CB  . SER D 4 145 ? 101.771 147.792 64.812  1.00 104.05 ? 145 SER E CB  1 
ATOM 5803 O OG  . SER D 4 145 ? 102.402 148.360 65.946  1.00 104.20 ? 145 SER E OG  1 
ATOM 5804 N N   . SER D 4 146 ? 101.927 146.100 62.122  1.00 116.88 ? 146 SER E N   1 
ATOM 5805 C CA  . SER D 4 146 ? 101.223 145.589 60.956  1.00 118.63 ? 146 SER E CA  1 
ATOM 5806 C C   . SER D 4 146 ? 102.224 145.195 59.881  1.00 119.95 ? 146 SER E C   1 
ATOM 5807 O O   . SER D 4 146 ? 103.314 145.763 59.784  1.00 119.64 ? 146 SER E O   1 
ATOM 5808 C CB  . SER D 4 146 ? 100.234 146.620 60.398  1.00 117.93 ? 146 SER E CB  1 
ATOM 5809 O OG  . SER D 4 146 ? 100.900 147.811 60.017  1.00 119.49 ? 146 SER E OG  1 
ATOM 5810 N N   . VAL D 4 147 ? 101.836 144.211 59.075  1.00 125.80 ? 147 VAL E N   1 
ATOM 5811 C CA  . VAL D 4 147 ? 102.659 143.716 57.973  1.00 126.61 ? 147 VAL E CA  1 
ATOM 5812 C C   . VAL D 4 147 ? 101.765 143.514 56.756  1.00 126.85 ? 147 VAL E C   1 
ATOM 5813 O O   . VAL D 4 147 ? 100.840 142.690 56.801  1.00 125.58 ? 147 VAL E O   1 
ATOM 5814 C CB  . VAL D 4 147 ? 103.377 142.408 58.343  1.00 126.60 ? 147 VAL E CB  1 
ATOM 5815 C CG1 . VAL D 4 147 ? 104.099 141.844 57.131  1.00 126.54 ? 147 VAL E CG1 1 
ATOM 5816 C CG2 . VAL D 4 147 ? 104.350 142.626 59.487  1.00 123.95 ? 147 VAL E CG2 1 
ATOM 5817 N N   . PRO D 4 148 ? 101.994 144.230 55.655  1.00 135.32 ? 148 PRO E N   1 
ATOM 5818 C CA  . PRO D 4 148 ? 101.207 143.974 54.441  1.00 135.51 ? 148 PRO E CA  1 
ATOM 5819 C C   . PRO D 4 148 ? 101.659 142.681 53.778  1.00 135.14 ? 148 PRO E C   1 
ATOM 5820 O O   . PRO D 4 148 ? 102.847 142.483 53.515  1.00 133.98 ? 148 PRO E O   1 
ATOM 5821 C CB  . PRO D 4 148 ? 101.502 145.195 53.564  1.00 134.87 ? 148 PRO E CB  1 
ATOM 5822 C CG  . PRO D 4 148 ? 102.853 145.651 54.011  1.00 134.69 ? 148 PRO E CG  1 
ATOM 5823 C CD  . PRO D 4 148 ? 102.934 145.351 55.485  1.00 133.85 ? 148 PRO E CD  1 
ATOM 5824 N N   . VAL D 4 149 ? 100.698 141.796 53.510  1.00 134.75 ? 149 VAL E N   1 
ATOM 5825 C CA  . VAL D 4 149 ? 100.991 140.465 52.999  1.00 134.86 ? 149 VAL E CA  1 
ATOM 5826 C C   . VAL D 4 149 ? 100.108 140.176 51.793  1.00 133.80 ? 149 VAL E C   1 
ATOM 5827 O O   . VAL D 4 149 ? 99.069  140.805 51.583  1.00 132.59 ? 149 VAL E O   1 
ATOM 5828 C CB  . VAL D 4 149 ? 100.795 139.372 54.073  1.00 134.94 ? 149 VAL E CB  1 
ATOM 5829 C CG1 . VAL D 4 149 ? 101.683 139.639 55.276  1.00 133.47 ? 149 VAL E CG1 1 
ATOM 5830 C CG2 . VAL D 4 149 ? 99.335  139.291 54.487  1.00 132.97 ? 149 VAL E CG2 1 
ATOM 5831 N N   . THR D 4 150 ? 100.545 139.205 50.998  1.00 134.60 ? 150 THR E N   1 
ATOM 5832 C CA  . THR D 4 150 ? 99.814  138.695 49.852  1.00 135.13 ? 150 THR E CA  1 
ATOM 5833 C C   . THR D 4 150 ? 99.748  137.178 49.930  1.00 133.61 ? 150 THR E C   1 
ATOM 5834 O O   . THR D 4 150 ? 100.678 136.540 50.433  1.00 133.31 ? 150 THR E O   1 
ATOM 5835 C CB  . THR D 4 150 ? 100.481 139.110 48.532  1.00 134.08 ? 150 THR E CB  1 
ATOM 5836 O OG1 . THR D 4 150 ? 101.843 138.666 48.522  1.00 133.12 ? 150 THR E OG1 1 
ATOM 5837 C CG2 . THR D 4 150 ? 100.443 140.622 48.364  1.00 132.50 ? 150 THR E CG2 1 
ATOM 5838 N N   . PRO D 4 151 ? 98.660  136.576 49.451  1.00 133.43 ? 151 PRO E N   1 
ATOM 5839 C CA  . PRO D 4 151 ? 98.520  135.119 49.556  1.00 132.99 ? 151 PRO E CA  1 
ATOM 5840 C C   . PRO D 4 151 ? 99.633  134.393 48.813  1.00 131.86 ? 151 PRO E C   1 
ATOM 5841 O O   . PRO D 4 151 ? 100.097 134.836 47.760  1.00 131.91 ? 151 PRO E O   1 
ATOM 5842 C CB  . PRO D 4 151 ? 97.151  134.847 48.924  1.00 132.30 ? 151 PRO E CB  1 
ATOM 5843 C CG  . PRO D 4 151 ? 96.411  136.136 49.058  1.00 132.33 ? 151 PRO E CG  1 
ATOM 5844 C CD  . PRO D 4 151 ? 97.448  137.209 48.906  1.00 132.68 ? 151 PRO E CD  1 
ATOM 5845 N N   . GLY D 4 152 ? 100.061 133.267 49.378  1.00 131.28 ? 152 GLY E N   1 
ATOM 5846 C CA  . GLY D 4 152 ? 101.094 132.448 48.784  1.00 131.17 ? 152 GLY E CA  1 
ATOM 5847 C C   . GLY D 4 152 ? 102.513 132.890 49.062  1.00 131.31 ? 152 GLY E C   1 
ATOM 5848 O O   . GLY D 4 152 ? 103.449 132.254 48.562  1.00 130.14 ? 152 GLY E O   1 
ATOM 5849 N N   . GLU D 4 153 ? 102.709 133.949 49.841  1.00 125.79 ? 153 GLU E N   1 
ATOM 5850 C CA  . GLU D 4 153 ? 104.031 134.479 50.132  1.00 125.16 ? 153 GLU E CA  1 
ATOM 5851 C C   . GLU D 4 153 ? 104.399 134.197 51.584  1.00 125.24 ? 153 GLU E C   1 
ATOM 5852 O O   . GLU D 4 153 ? 103.538 134.180 52.467  1.00 125.95 ? 153 GLU E O   1 
ATOM 5853 C CB  . GLU D 4 153 ? 104.081 135.985 49.850  1.00 125.94 ? 153 GLU E CB  1 
ATOM 5854 C CG  . GLU D 4 153 ? 105.474 136.591 49.856  1.00 125.79 ? 153 GLU E CG  1 
ATOM 5855 C CD  . GLU D 4 153 ? 105.782 137.326 51.144  1.00 127.23 ? 153 GLU E CD  1 
ATOM 5856 O OE1 . GLU D 4 153 ? 104.875 137.440 51.995  1.00 125.67 ? 153 GLU E OE1 1 
ATOM 5857 O OE2 . GLU D 4 153 ? 106.930 137.789 51.307  1.00 127.12 ? 153 GLU E OE2 1 
ATOM 5858 N N   . SER D 4 154 ? 105.689 133.975 51.823  1.00 118.71 ? 154 SER E N   1 
ATOM 5859 C CA  . SER D 4 154 ? 106.163 133.629 53.155  1.00 120.07 ? 154 SER E CA  1 
ATOM 5860 C C   . SER D 4 154 ? 106.280 134.874 54.023  1.00 118.94 ? 154 SER E C   1 
ATOM 5861 O O   . SER D 4 154 ? 106.788 135.910 53.585  1.00 117.57 ? 154 SER E O   1 
ATOM 5862 C CB  . SER D 4 154 ? 107.515 132.921 53.074  1.00 118.39 ? 154 SER E CB  1 
ATOM 5863 O OG  . SER D 4 154 ? 107.422 131.731 52.311  1.00 119.16 ? 154 SER E OG  1 
ATOM 5864 N N   . VAL D 4 155 ? 105.815 134.764 55.265  1.00 104.86 ? 155 VAL E N   1 
ATOM 5865 C CA  . VAL D 4 155 ? 105.807 135.875 56.207  1.00 102.38 ? 155 VAL E CA  1 
ATOM 5866 C C   . VAL D 4 155 ? 106.498 135.433 57.488  1.00 101.48 ? 155 VAL E C   1 
ATOM 5867 O O   . VAL D 4 155 ? 106.324 134.295 57.936  1.00 102.58 ? 155 VAL E O   1 
ATOM 5868 C CB  . VAL D 4 155 ? 104.371 136.357 56.505  1.00 105.63 ? 155 VAL E CB  1 
ATOM 5869 C CG1 . VAL D 4 155 ? 104.392 137.640 57.321  1.00 102.79 ? 155 VAL E CG1 1 
ATOM 5870 C CG2 . VAL D 4 155 ? 103.597 136.554 55.214  1.00 106.55 ? 155 VAL E CG2 1 
ATOM 5871 N N   . SER D 4 156 ? 107.286 136.329 58.072  1.00 90.80  ? 156 SER E N   1 
ATOM 5872 C CA  . SER D 4 156 ? 107.938 136.093 59.351  1.00 92.62  ? 156 SER E CA  1 
ATOM 5873 C C   . SER D 4 156 ? 107.518 137.170 60.339  1.00 92.94  ? 156 SER E C   1 
ATOM 5874 O O   . SER D 4 156 ? 107.499 138.359 60.006  1.00 93.49  ? 156 SER E O   1 
ATOM 5875 C CB  . SER D 4 156 ? 109.462 136.073 59.209  1.00 92.97  ? 156 SER E CB  1 
ATOM 5876 O OG  . SER D 4 156 ? 109.881 135.008 58.374  1.00 94.99  ? 156 SER E OG  1 
ATOM 5877 N N   . ILE D 4 157 ? 107.191 136.747 61.557  1.00 82.37  ? 157 ILE E N   1 
ATOM 5878 C CA  . ILE D 4 157 ? 106.766 137.638 62.629  1.00 80.79  ? 157 ILE E CA  1 
ATOM 5879 C C   . ILE D 4 157 ? 107.758 137.499 63.772  1.00 78.57  ? 157 ILE E C   1 
ATOM 5880 O O   . ILE D 4 157 ? 108.112 136.380 64.157  1.00 80.99  ? 157 ILE E O   1 
ATOM 5881 C CB  . ILE D 4 157 ? 105.337 137.315 63.101  1.00 80.45  ? 157 ILE E CB  1 
ATOM 5882 C CG1 . ILE D 4 157 ? 104.362 137.397 61.928  1.00 80.48  ? 157 ILE E CG1 1 
ATOM 5883 C CG2 . ILE D 4 157 ? 104.912 138.261 64.207  1.00 83.48  ? 157 ILE E CG2 1 
ATOM 5884 C CD1 . ILE D 4 157 ? 102.935 137.096 62.308  1.00 81.75  ? 157 ILE E CD1 1 
ATOM 5885 N N   . SER D 4 158 ? 108.195 138.628 64.320  1.00 70.85  ? 158 SER E N   1 
ATOM 5886 C CA  . SER D 4 158 ? 109.239 138.651 65.332  1.00 73.17  ? 158 SER E CA  1 
ATOM 5887 C C   . SER D 4 158 ? 108.662 138.997 66.697  1.00 74.30  ? 158 SER E C   1 
ATOM 5888 O O   . SER D 4 158 ? 107.740 139.811 66.807  1.00 79.53  ? 158 SER E O   1 
ATOM 5889 C CB  . SER D 4 158 ? 110.329 139.662 64.967  1.00 73.88  ? 158 SER E CB  1 
ATOM 5890 O OG  . SER D 4 158 ? 110.916 139.350 63.718  1.00 77.28  ? 158 SER E OG  1 
ATOM 5891 N N   . CYS D 4 159 ? 109.216 138.373 67.731  1.00 70.10  ? 159 CYS E N   1 
ATOM 5892 C CA  . CYS D 4 159 ? 108.845 138.642 69.110  1.00 70.63  ? 159 CYS E CA  1 
ATOM 5893 C C   . CYS D 4 159 ? 110.118 138.727 69.938  1.00 73.59  ? 159 CYS E C   1 
ATOM 5894 O O   . CYS D 4 159 ? 111.102 138.035 69.664  1.00 74.11  ? 159 CYS E O   1 
ATOM 5895 C CB  . CYS D 4 159 ? 107.910 137.554 69.662  1.00 70.78  ? 159 CYS E CB  1 
ATOM 5896 S SG  . CYS D 4 159 ? 107.348 137.773 71.370  1.00 83.52  ? 159 CYS E SG  1 
ATOM 5897 N N   . ARG D 4 160 ? 110.090 139.579 70.958  1.00 71.17  ? 160 ARG E N   1 
ATOM 5898 C CA  . ARG D 4 160 ? 111.225 139.779 71.845  1.00 69.81  ? 160 ARG E CA  1 
ATOM 5899 C C   . ARG D 4 160 ? 110.758 139.710 73.289  1.00 68.72  ? 160 ARG E C   1 
ATOM 5900 O O   . ARG D 4 160 ? 109.609 140.028 73.600  1.00 76.72  ? 160 ARG E O   1 
ATOM 5901 C CB  . ARG D 4 160 ? 111.914 141.123 71.589  1.00 71.10  ? 160 ARG E CB  1 
ATOM 5902 C CG  . ARG D 4 160 ? 112.594 141.229 70.237  1.00 70.07  ? 160 ARG E CG  1 
ATOM 5903 C CD  . ARG D 4 160 ? 113.184 142.612 70.017  1.00 71.52  ? 160 ARG E CD  1 
ATOM 5904 N NE  . ARG D 4 160 ? 114.144 142.972 71.054  1.00 75.87  ? 160 ARG E NE  1 
ATOM 5905 C CZ  . ARG D 4 160 ? 113.896 143.813 72.048  1.00 75.54  ? 160 ARG E CZ  1 
ATOM 5906 N NH1 . ARG D 4 160 ? 112.723 144.413 72.170  1.00 72.73  ? 160 ARG E NH1 1 
ATOM 5907 N NH2 . ARG D 4 160 ? 114.848 144.058 72.944  1.00 72.97  ? 160 ARG E NH2 1 
ATOM 5908 N N   . SER D 4 161 ? 111.663 139.299 74.170  1.00 56.58  ? 161 SER E N   1 
ATOM 5909 C CA  . SER D 4 161 ? 111.377 139.210 75.593  1.00 61.51  ? 161 SER E CA  1 
ATOM 5910 C C   . SER D 4 161 ? 112.481 139.898 76.379  1.00 60.12  ? 161 SER E C   1 
ATOM 5911 O O   . SER D 4 161 ? 113.652 139.851 75.993  1.00 64.72  ? 161 SER E O   1 
ATOM 5912 C CB  . SER D 4 161 ? 111.245 137.755 76.044  1.00 60.52  ? 161 SER E CB  1 
ATOM 5913 O OG  . SER D 4 161 ? 112.452 137.046 75.842  1.00 65.30  ? 161 SER E OG  1 
ATOM 5914 N N   . SER D 4 162 ? 112.098 140.546 77.481  1.00 57.22  ? 162 SER E N   1 
ATOM 5915 C CA  . SER D 4 162 ? 113.083 141.207 78.328  1.00 57.34  ? 162 SER E CA  1 
ATOM 5916 C C   . SER D 4 162 ? 113.997 140.203 79.019  1.00 62.75  ? 162 SER E C   1 
ATOM 5917 O O   . SER D 4 162 ? 115.176 140.495 79.246  1.00 64.22  ? 162 SER E O   1 
ATOM 5918 C CB  . SER D 4 162 ? 112.381 142.085 79.362  1.00 57.22  ? 162 SER E CB  1 
ATOM 5919 O OG  . SER D 4 162 ? 111.542 141.311 80.198  1.00 66.32  ? 162 SER E OG  1 
ATOM 5920 N N   . LYS D 4 163 ? 113.480 139.027 79.354  1.00 61.08  ? 163 LYS E N   1 
ATOM 5921 C CA  . LYS D 4 163 ? 114.254 137.967 79.977  1.00 59.98  ? 163 LYS E CA  1 
ATOM 5922 C C   . LYS D 4 163 ? 114.351 136.778 79.030  1.00 60.48  ? 163 LYS E C   1 
ATOM 5923 O O   . LYS D 4 163 ? 113.527 136.606 78.129  1.00 63.81  ? 163 LYS E O   1 
ATOM 5924 C CB  . LYS D 4 163 ? 113.618 137.537 81.306  1.00 57.57  ? 163 LYS E CB  1 
ATOM 5925 C CG  . LYS D 4 163 ? 114.502 136.662 82.179  1.00 57.81  ? 163 LYS E CG  1 
ATOM 5926 C CD  . LYS D 4 163 ? 113.762 136.161 83.405  1.00 58.93  ? 163 LYS E CD  1 
ATOM 5927 C CE  . LYS D 4 163 ? 113.325 137.310 84.292  1.00 60.78  ? 163 LYS E CE  1 
ATOM 5928 N NZ  . LYS D 4 163 ? 112.618 136.827 85.509  1.00 57.68  ? 163 LYS E NZ  1 
ATOM 5929 N N   . SER D 4 164 ? 115.378 135.959 79.234  1.00 61.36  ? 164 SER E N   1 
ATOM 5930 C CA  . SER D 4 164 ? 115.521 134.733 78.462  1.00 64.89  ? 164 SER E CA  1 
ATOM 5931 C C   . SER D 4 164 ? 114.425 133.750 78.852  1.00 68.94  ? 164 SER E C   1 
ATOM 5932 O O   . SER D 4 164 ? 114.271 133.417 80.032  1.00 64.28  ? 164 SER E O   1 
ATOM 5933 C CB  . SER D 4 164 ? 116.899 134.120 78.690  1.00 62.11  ? 164 SER E CB  1 
ATOM 5934 O OG  . SER D 4 164 ? 117.052 132.924 77.947  1.00 58.68  ? 164 SER E OG  1 
ATOM 5935 N N   . LEU D 4 165 ? 113.664 133.285 77.863  1.00 62.48  ? 165 LEU E N   1 
ATOM 5936 C CA  . LEU D 4 165 ? 112.598 132.323 78.104  1.00 54.19  ? 165 LEU E CA  1 
ATOM 5937 C C   . LEU D 4 165 ? 113.088 130.885 78.126  1.00 55.07  ? 165 LEU E C   1 
ATOM 5938 O O   . LEU D 4 165 ? 112.284 129.981 78.375  1.00 62.99  ? 165 LEU E O   1 
ATOM 5939 C CB  . LEU D 4 165 ? 111.498 132.471 77.051  1.00 52.69  ? 165 LEU E CB  1 
ATOM 5940 C CG  . LEU D 4 165 ? 110.698 133.769 77.116  1.00 50.11  ? 165 LEU E CG  1 
ATOM 5941 C CD1 . LEU D 4 165 ? 109.561 133.750 76.115  1.00 47.93  ? 165 LEU E CD1 1 
ATOM 5942 C CD2 . LEU D 4 165 ? 110.178 133.988 78.520  1.00 50.12  ? 165 LEU E CD2 1 
ATOM 5943 N N   . LEU D 4 166 ? 114.372 130.646 77.878  1.00 56.21  ? 166 LEU E N   1 
ATOM 5944 C CA  . LEU D 4 166 ? 114.915 129.297 77.940  1.00 56.44  ? 166 LEU E CA  1 
ATOM 5945 C C   . LEU D 4 166 ? 115.155 128.921 79.394  1.00 53.75  ? 166 LEU E C   1 
ATOM 5946 O O   . LEU D 4 166 ? 115.943 129.571 80.089  1.00 57.55  ? 166 LEU E O   1 
ATOM 5947 C CB  . LEU D 4 166 ? 116.208 129.208 77.135  1.00 59.39  ? 166 LEU E CB  1 
ATOM 5948 C CG  . LEU D 4 166 ? 116.964 127.882 77.204  1.00 61.16  ? 166 LEU E CG  1 
ATOM 5949 C CD1 . LEU D 4 166 ? 116.117 126.752 76.657  1.00 59.55  ? 166 LEU E CD1 1 
ATOM 5950 C CD2 . LEU D 4 166 ? 118.279 127.978 76.452  1.00 57.71  ? 166 LEU E CD2 1 
ATOM 5951 N N   . HIS D 4 167 ? 114.479 127.875 79.851  1.00 49.42  ? 167 HIS E N   1 
ATOM 5952 C CA  . HIS D 4 167 ? 114.632 127.384 81.208  1.00 48.86  ? 167 HIS E CA  1 
ATOM 5953 C C   . HIS D 4 167 ? 115.757 126.357 81.279  1.00 55.95  ? 167 HIS E C   1 
ATOM 5954 O O   . HIS D 4 167 ? 116.235 125.843 80.266  1.00 54.62  ? 167 HIS E O   1 
ATOM 5955 C CB  . HIS D 4 167 ? 113.320 126.781 81.706  1.00 48.78  ? 167 HIS E CB  1 
ATOM 5956 C CG  . HIS D 4 167 ? 113.223 126.691 83.196  1.00 49.33  ? 167 HIS E CG  1 
ATOM 5957 N ND1 . HIS D 4 167 ? 113.567 125.557 83.898  1.00 48.88  ? 167 HIS E ND1 1 
ATOM 5958 C CD2 . HIS D 4 167 ? 112.809 127.592 84.118  1.00 54.79  ? 167 HIS E CD2 1 
ATOM 5959 C CE1 . HIS D 4 167 ? 113.377 125.764 85.188  1.00 51.26  ? 167 HIS E CE1 1 
ATOM 5960 N NE2 . HIS D 4 167 ? 112.916 126.991 85.348  1.00 53.07  ? 167 HIS E NE2 1 
ATOM 5961 N N   . SER D 4 168 ? 116.187 126.062 82.505  1.00 51.49  ? 168 SER E N   1 
ATOM 5962 C CA  . SER D 4 168 ? 117.261 125.103 82.715  1.00 53.80  ? 168 SER E CA  1 
ATOM 5963 C C   . SER D 4 168 ? 116.864 123.678 82.355  1.00 55.53  ? 168 SER E C   1 
ATOM 5964 O O   . SER D 4 168 ? 117.744 122.815 82.272  1.00 58.29  ? 168 SER E O   1 
ATOM 5965 C CB  . SER D 4 168 ? 117.730 125.155 84.169  1.00 55.36  ? 168 SER E CB  1 
ATOM 5966 O OG  . SER D 4 168 ? 116.665 124.864 85.055  1.00 52.80  ? 168 SER E OG  1 
ATOM 5967 N N   . ASN D 4 169 ? 115.577 123.406 82.142  1.00 44.45  ? 169 ASN E N   1 
ATOM 5968 C CA  . ASN D 4 169 ? 115.132 122.080 81.737  1.00 48.66  ? 169 ASN E CA  1 
ATOM 5969 C C   . ASN D 4 169 ? 115.133 121.893 80.225  1.00 50.86  ? 169 ASN E C   1 
ATOM 5970 O O   . ASN D 4 169 ? 114.763 120.816 79.748  1.00 57.44  ? 169 ASN E O   1 
ATOM 5971 C CB  . ASN D 4 169 ? 113.735 121.791 82.300  1.00 43.15  ? 169 ASN E CB  1 
ATOM 5972 C CG  . ASN D 4 169 ? 112.739 122.889 81.998  1.00 49.53  ? 169 ASN E CG  1 
ATOM 5973 O OD1 . ASN D 4 169 ? 112.863 123.603 81.007  1.00 55.82  ? 169 ASN E OD1 1 
ATOM 5974 N ND2 . ASN D 4 169 ? 111.741 123.030 82.857  1.00 53.31  ? 169 ASN E ND2 1 
ATOM 5975 N N   . GLY D 4 170 ? 115.535 122.910 79.466  1.00 37.15  ? 170 GLY E N   1 
ATOM 5976 C CA  . GLY D 4 170 ? 115.628 122.833 78.028  1.00 41.62  ? 170 GLY E CA  1 
ATOM 5977 C C   . GLY D 4 170 ? 114.440 123.400 77.282  1.00 48.67  ? 170 GLY E C   1 
ATOM 5978 O O   . GLY D 4 170 ? 114.545 123.643 76.075  1.00 52.83  ? 170 GLY E O   1 
ATOM 5979 N N   . ASN D 4 171 ? 113.318 123.617 77.960  1.00 53.63  ? 171 ASN E N   1 
ATOM 5980 C CA  . ASN D 4 171 ? 112.147 124.200 77.325  1.00 48.90  ? 171 ASN E CA  1 
ATOM 5981 C C   . ASN D 4 171 ? 112.303 125.708 77.198  1.00 46.76  ? 171 ASN E C   1 
ATOM 5982 O O   . ASN D 4 171 ? 112.883 126.362 78.068  1.00 50.25  ? 171 ASN E O   1 
ATOM 5983 C CB  . ASN D 4 171 ? 110.885 123.875 78.121  1.00 46.24  ? 171 ASN E CB  1 
ATOM 5984 C CG  . ASN D 4 171 ? 110.544 122.405 78.096  1.00 51.29  ? 171 ASN E CG  1 
ATOM 5985 O OD1 . ASN D 4 171 ? 110.448 121.762 79.139  1.00 47.94  ? 171 ASN E OD1 1 
ATOM 5986 N ND2 . ASN D 4 171 ? 110.352 121.864 76.902  1.00 50.97  ? 171 ASN E ND2 1 
ATOM 5987 N N   . THR D 4 172 ? 111.776 126.258 76.110  1.00 50.24  ? 172 THR E N   1 
ATOM 5988 C CA  . THR D 4 172 ? 111.656 127.700 75.928  1.00 48.28  ? 172 THR E CA  1 
ATOM 5989 C C   . THR D 4 172 ? 110.170 128.018 75.896  1.00 53.37  ? 172 THR E C   1 
ATOM 5990 O O   . THR D 4 172 ? 109.497 127.762 74.894  1.00 62.18  ? 172 THR E O   1 
ATOM 5991 C CB  . THR D 4 172 ? 112.344 128.163 74.647  1.00 55.02  ? 172 THR E CB  1 
ATOM 5992 O OG1 . THR D 4 172 ? 113.717 127.756 74.666  1.00 59.43  ? 172 THR E OG1 1 
ATOM 5993 C CG2 . THR D 4 172 ? 112.273 129.672 74.527  1.00 51.39  ? 172 THR E CG2 1 
ATOM 5994 N N   . TYR D 4 173 ? 109.666 128.590 76.987  1.00 41.72  ? 173 TYR E N   1 
ATOM 5995 C CA  . TYR D 4 173 ? 108.227 128.729 77.200  1.00 40.20  ? 173 TYR E CA  1 
ATOM 5996 C C   . TYR D 4 173 ? 107.695 129.970 76.483  1.00 41.29  ? 173 TYR E C   1 
ATOM 5997 O O   . TYR D 4 173 ? 107.348 130.988 77.084  1.00 50.09  ? 173 TYR E O   1 
ATOM 5998 C CB  . TYR D 4 173 ? 107.922 128.763 78.688  1.00 43.31  ? 173 TYR E CB  1 
ATOM 5999 C CG  . TYR D 4 173 ? 108.350 127.510 79.406  1.00 43.03  ? 173 TYR E CG  1 
ATOM 6000 C CD1 . TYR D 4 173 ? 107.610 126.346 79.309  1.00 46.04  ? 173 TYR E CD1 1 
ATOM 6001 C CD2 . TYR D 4 173 ? 109.493 127.494 80.185  1.00 48.16  ? 173 TYR E CD2 1 
ATOM 6002 C CE1 . TYR D 4 173 ? 107.998 125.201 79.963  1.00 43.34  ? 173 TYR E CE1 1 
ATOM 6003 C CE2 . TYR D 4 173 ? 109.888 126.355 80.844  1.00 49.74  ? 173 TYR E CE2 1 
ATOM 6004 C CZ  . TYR D 4 173 ? 109.136 125.212 80.732  1.00 52.18  ? 173 TYR E CZ  1 
ATOM 6005 O OH  . TYR D 4 173 ? 109.529 124.070 81.390  1.00 59.67  ? 173 TYR E OH  1 
ATOM 6006 N N   . LEU D 4 174 ? 107.630 129.866 75.161  1.00 39.30  ? 174 LEU E N   1 
ATOM 6007 C CA  . LEU D 4 174 ? 107.042 130.899 74.322  1.00 44.96  ? 174 LEU E CA  1 
ATOM 6008 C C   . LEU D 4 174 ? 105.892 130.298 73.529  1.00 45.54  ? 174 LEU E C   1 
ATOM 6009 O O   . LEU D 4 174 ? 106.028 129.215 72.953  1.00 42.79  ? 174 LEU E O   1 
ATOM 6010 C CB  . LEU D 4 174 ? 108.071 131.504 73.368  1.00 47.75  ? 174 LEU E CB  1 
ATOM 6011 C CG  . LEU D 4 174 ? 107.453 132.506 72.394  1.00 39.36  ? 174 LEU E CG  1 
ATOM 6012 C CD1 . LEU D 4 174 ? 107.619 133.920 72.897  1.00 42.17  ? 174 LEU E CD1 1 
ATOM 6013 C CD2 . LEU D 4 174 ? 108.034 132.342 71.015  1.00 48.59  ? 174 LEU E CD2 1 
ATOM 6014 N N   . TYR D 4 175 ? 104.771 131.010 73.488  1.00 52.19  ? 175 TYR E N   1 
ATOM 6015 C CA  . TYR D 4 175 ? 103.563 130.550 72.824  1.00 39.97  ? 175 TYR E CA  1 
ATOM 6016 C C   . TYR D 4 175 ? 103.164 131.543 71.743  1.00 36.80  ? 175 TYR E C   1 
ATOM 6017 O O   . TYR D 4 175 ? 103.404 132.746 71.864  1.00 48.82  ? 175 TYR E O   1 
ATOM 6018 C CB  . TYR D 4 175 ? 102.416 130.373 73.828  1.00 41.07  ? 175 TYR E CB  1 
ATOM 6019 C CG  . TYR D 4 175 ? 102.598 129.194 74.754  1.00 44.64  ? 175 TYR E CG  1 
ATOM 6020 C CD1 . TYR D 4 175 ? 103.626 129.165 75.683  1.00 44.72  ? 175 TYR E CD1 1 
ATOM 6021 C CD2 . TYR D 4 175 ? 101.733 128.116 74.704  1.00 36.58  ? 175 TYR E CD2 1 
ATOM 6022 C CE1 . TYR D 4 175 ? 103.794 128.091 76.522  1.00 41.89  ? 175 TYR E CE1 1 
ATOM 6023 C CE2 . TYR D 4 175 ? 101.891 127.042 75.545  1.00 40.95  ? 175 TYR E CE2 1 
ATOM 6024 C CZ  . TYR D 4 175 ? 102.924 127.032 76.449  1.00 44.75  ? 175 TYR E CZ  1 
ATOM 6025 O OH  . TYR D 4 175 ? 103.082 125.956 77.287  1.00 42.95  ? 175 TYR E OH  1 
ATOM 6026 N N   . TRP D 4 176 ? 102.556 131.028 70.681  1.00 42.70  ? 176 TRP E N   1 
ATOM 6027 C CA  . TRP D 4 176 ? 102.051 131.847 69.590  1.00 43.63  ? 176 TRP E CA  1 
ATOM 6028 C C   . TRP D 4 176 ? 100.555 131.627 69.448  1.00 46.22  ? 176 TRP E C   1 
ATOM 6029 O O   . TRP D 4 176 ? 100.090 130.485 69.443  1.00 58.89  ? 176 TRP E O   1 
ATOM 6030 C CB  . TRP D 4 176 ? 102.753 131.520 68.269  1.00 51.99  ? 176 TRP E CB  1 
ATOM 6031 C CG  . TRP D 4 176 ? 104.139 132.060 68.163  1.00 48.49  ? 176 TRP E CG  1 
ATOM 6032 C CD1 . TRP D 4 176 ? 105.300 131.374 68.339  1.00 52.98  ? 176 TRP E CD1 1 
ATOM 6033 C CD2 . TRP D 4 176 ? 104.511 133.405 67.848  1.00 51.16  ? 176 TRP E CD2 1 
ATOM 6034 N NE1 . TRP D 4 176 ? 106.376 132.206 68.156  1.00 54.37  ? 176 TRP E NE1 1 
ATOM 6035 C CE2 . TRP D 4 176 ? 105.917 133.461 67.853  1.00 57.09  ? 176 TRP E CE2 1 
ATOM 6036 C CE3 . TRP D 4 176 ? 103.792 134.568 67.562  1.00 50.96  ? 176 TRP E CE3 1 
ATOM 6037 C CZ2 . TRP D 4 176 ? 106.618 134.633 67.585  1.00 51.89  ? 176 TRP E CZ2 1 
ATOM 6038 C CZ3 . TRP D 4 176 ? 104.489 135.729 67.298  1.00 58.20  ? 176 TRP E CZ3 1 
ATOM 6039 C CH2 . TRP D 4 176 ? 105.887 135.753 67.311  1.00 54.38  ? 176 TRP E CH2 1 
ATOM 6040 N N   . PHE D 4 177 ? 99.810  132.720 69.333  1.00 43.72  ? 177 PHE E N   1 
ATOM 6041 C CA  . PHE D 4 177 ? 98.369  132.670 69.161  1.00 44.02  ? 177 PHE E CA  1 
ATOM 6042 C C   . PHE D 4 177 ? 97.984  133.461 67.923  1.00 50.85  ? 177 PHE E C   1 
ATOM 6043 O O   . PHE D 4 177 ? 98.660  134.420 67.546  1.00 61.80  ? 177 PHE E O   1 
ATOM 6044 C CB  . PHE D 4 177 ? 97.630  133.231 70.380  1.00 45.61  ? 177 PHE E CB  1 
ATOM 6045 C CG  . PHE D 4 177 ? 97.922  132.500 71.651  1.00 45.61  ? 177 PHE E CG  1 
ATOM 6046 C CD1 . PHE D 4 177 ? 97.222  131.356 71.977  1.00 46.09  ? 177 PHE E CD1 1 
ATOM 6047 C CD2 . PHE D 4 177 ? 98.888  132.958 72.523  1.00 47.39  ? 177 PHE E CD2 1 
ATOM 6048 C CE1 . PHE D 4 177 ? 97.486  130.679 73.143  1.00 40.78  ? 177 PHE E CE1 1 
ATOM 6049 C CE2 . PHE D 4 177 ? 99.153  132.283 73.691  1.00 47.67  ? 177 PHE E CE2 1 
ATOM 6050 C CZ  . PHE D 4 177 ? 98.450  131.143 74.000  1.00 39.37  ? 177 PHE E CZ  1 
ATOM 6051 N N   . LEU D 4 178 ? 96.889  133.049 67.293  1.00 53.93  ? 178 LEU E N   1 
ATOM 6052 C CA  . LEU D 4 178 ? 96.333  133.750 66.143  1.00 56.88  ? 178 LEU E CA  1 
ATOM 6053 C C   . LEU D 4 178 ? 94.883  134.081 66.441  1.00 62.90  ? 178 LEU E C   1 
ATOM 6054 O O   . LEU D 4 178 ? 94.092  133.185 66.753  1.00 68.33  ? 178 LEU E O   1 
ATOM 6055 C CB  . LEU D 4 178 ? 96.441  132.909 64.869  1.00 60.68  ? 178 LEU E CB  1 
ATOM 6056 C CG  . LEU D 4 178 ? 95.655  133.398 63.651  1.00 62.25  ? 178 LEU E CG  1 
ATOM 6057 C CD1 . LEU D 4 178 ? 96.057  134.808 63.270  1.00 60.55  ? 178 LEU E CD1 1 
ATOM 6058 C CD2 . LEU D 4 178 ? 95.854  132.454 62.481  1.00 64.76  ? 178 LEU E CD2 1 
ATOM 6059 N N   . GLN D 4 179 ? 94.536  135.357 66.340  1.00 64.35  ? 179 GLN E N   1 
ATOM 6060 C CA  . GLN D 4 179 ? 93.168  135.823 66.525  1.00 59.86  ? 179 GLN E CA  1 
ATOM 6061 C C   . GLN D 4 179 ? 92.676  136.371 65.192  1.00 65.47  ? 179 GLN E C   1 
ATOM 6062 O O   . GLN D 4 179 ? 92.980  137.509 64.827  1.00 66.28  ? 179 GLN E O   1 
ATOM 6063 C CB  . GLN D 4 179 ? 93.090  136.877 67.623  1.00 54.20  ? 179 GLN E CB  1 
ATOM 6064 C CG  . GLN D 4 179 ? 91.674  137.246 68.001  1.00 59.16  ? 179 GLN E CG  1 
ATOM 6065 C CD  . GLN D 4 179 ? 91.615  138.333 69.044  1.00 65.62  ? 179 GLN E CD  1 
ATOM 6066 O OE1 . GLN D 4 179 ? 92.365  139.307 68.986  1.00 65.63  ? 179 GLN E OE1 1 
ATOM 6067 N NE2 . GLN D 4 179 ? 90.724  138.174 70.013  1.00 67.07  ? 179 GLN E NE2 1 
ATOM 6068 N N   . ARG D 4 180 ? 91.929  135.550 64.462  1.00 74.37  ? 180 ARG E N   1 
ATOM 6069 C CA  . ARG D 4 180 ? 91.317  136.001 63.227  1.00 73.44  ? 180 ARG E CA  1 
ATOM 6070 C C   . ARG D 4 180 ? 90.213  137.013 63.535  1.00 75.91  ? 180 ARG E C   1 
ATOM 6071 O O   . ARG D 4 180 ? 89.629  136.989 64.621  1.00 78.06  ? 180 ARG E O   1 
ATOM 6072 C CB  . ARG D 4 180 ? 90.750  134.814 62.456  1.00 76.31  ? 180 ARG E CB  1 
ATOM 6073 C CG  . ARG D 4 180 ? 91.796  133.787 62.065  1.00 78.29  ? 180 ARG E CG  1 
ATOM 6074 C CD  . ARG D 4 180 ? 91.176  132.615 61.332  1.00 77.85  ? 180 ARG E CD  1 
ATOM 6075 N NE  . ARG D 4 180 ? 92.186  131.653 60.907  1.00 80.86  ? 180 ARG E NE  1 
ATOM 6076 C CZ  . ARG D 4 180 ? 92.592  130.623 61.634  1.00 81.62  ? 180 ARG E CZ  1 
ATOM 6077 N NH1 . ARG D 4 180 ? 92.090  130.383 62.834  1.00 78.44  ? 180 ARG E NH1 1 
ATOM 6078 N NH2 . ARG D 4 180 ? 93.526  129.812 61.145  1.00 79.24  ? 180 ARG E NH2 1 
ATOM 6079 N N   . PRO D 4 181 ? 89.920  137.922 62.604  1.00 83.79  ? 181 PRO E N   1 
ATOM 6080 C CA  . PRO D 4 181 ? 88.912  138.961 62.874  1.00 80.64  ? 181 PRO E CA  1 
ATOM 6081 C C   . PRO D 4 181 ? 87.552  138.359 63.188  1.00 84.42  ? 181 PRO E C   1 
ATOM 6082 O O   . PRO D 4 181 ? 86.991  137.595 62.399  1.00 83.21  ? 181 PRO E O   1 
ATOM 6083 C CB  . PRO D 4 181 ? 88.889  139.775 61.574  1.00 80.25  ? 181 PRO E CB  1 
ATOM 6084 C CG  . PRO D 4 181 ? 89.475  138.872 60.540  1.00 79.58  ? 181 PRO E CG  1 
ATOM 6085 C CD  . PRO D 4 181 ? 90.502  138.061 61.259  1.00 84.28  ? 181 PRO E CD  1 
ATOM 6086 N N   . GLY D 4 182 ? 87.022  138.712 64.357  1.00 81.58  ? 182 GLY E N   1 
ATOM 6087 C CA  . GLY D 4 182 ? 85.745  138.208 64.812  1.00 78.63  ? 182 GLY E CA  1 
ATOM 6088 C C   . GLY D 4 182 ? 85.801  136.888 65.546  1.00 81.04  ? 182 GLY E C   1 
ATOM 6089 O O   . GLY D 4 182 ? 84.760  136.419 66.022  1.00 80.54  ? 182 GLY E O   1 
ATOM 6090 N N   . GLN D 4 183 ? 86.977  136.276 65.658  1.00 79.05  ? 183 GLN E N   1 
ATOM 6091 C CA  . GLN D 4 183 ? 87.134  134.962 66.257  1.00 74.52  ? 183 GLN E CA  1 
ATOM 6092 C C   . GLN D 4 183 ? 88.007  135.053 67.501  1.00 72.31  ? 183 GLN E C   1 
ATOM 6093 O O   . GLN D 4 183 ? 88.733  136.028 67.709  1.00 67.17  ? 183 GLN E O   1 
ATOM 6094 C CB  . GLN D 4 183 ? 87.737  133.963 65.263  1.00 71.04  ? 183 GLN E CB  1 
ATOM 6095 C CG  . GLN D 4 183 ? 86.857  133.690 64.057  1.00 73.21  ? 183 GLN E CG  1 
ATOM 6096 C CD  . GLN D 4 183 ? 87.433  132.628 63.142  1.00 80.86  ? 183 GLN E CD  1 
ATOM 6097 O OE1 . GLN D 4 183 ? 86.849  132.302 62.109  1.00 79.44  ? 183 GLN E OE1 1 
ATOM 6098 N NE2 . GLN D 4 183 ? 88.583  132.081 63.518  1.00 77.80  ? 183 GLN E NE2 1 
ATOM 6099 N N   . SER D 4 184 ? 87.924  134.017 68.325  1.00 68.12  ? 184 SER E N   1 
ATOM 6100 C CA  . SER D 4 184 ? 88.764  133.886 69.501  1.00 64.57  ? 184 SER E CA  1 
ATOM 6101 C C   . SER D 4 184 ? 90.183  133.489 69.109  1.00 65.49  ? 184 SER E C   1 
ATOM 6102 O O   . SER D 4 184 ? 90.410  132.947 68.025  1.00 62.24  ? 184 SER E O   1 
ATOM 6103 C CB  . SER D 4 184 ? 88.177  132.843 70.446  1.00 62.44  ? 184 SER E CB  1 
ATOM 6104 O OG  . SER D 4 184 ? 86.857  133.181 70.819  1.00 68.51  ? 184 SER E OG  1 
ATOM 6105 N N   . PRO D 4 185 ? 91.162  133.764 69.972  1.00 57.75  ? 185 PRO E N   1 
ATOM 6106 C CA  . PRO D 4 185 ? 92.534  133.343 69.679  1.00 50.45  ? 185 PRO E CA  1 
ATOM 6107 C C   . PRO D 4 185 ? 92.633  131.831 69.569  1.00 57.56  ? 185 PRO E C   1 
ATOM 6108 O O   . PRO D 4 185 ? 91.900  131.086 70.221  1.00 60.85  ? 185 PRO E O   1 
ATOM 6109 C CB  . PRO D 4 185 ? 93.331  133.872 70.874  1.00 44.92  ? 185 PRO E CB  1 
ATOM 6110 C CG  . PRO D 4 185 ? 92.519  134.996 71.395  1.00 52.13  ? 185 PRO E CG  1 
ATOM 6111 C CD  . PRO D 4 185 ? 91.095  134.602 71.181  1.00 59.41  ? 185 PRO E CD  1 
ATOM 6112 N N   . GLN D 4 186 ? 93.557  131.384 68.729  1.00 61.45  ? 186 GLN E N   1 
ATOM 6113 C CA  . GLN D 4 186 ? 93.827  129.969 68.547  1.00 58.00  ? 186 GLN E CA  1 
ATOM 6114 C C   . GLN D 4 186 ? 95.310  129.714 68.741  1.00 57.34  ? 186 GLN E C   1 
ATOM 6115 O O   . GLN D 4 186 ? 96.146  130.513 68.314  1.00 62.88  ? 186 GLN E O   1 
ATOM 6116 C CB  . GLN D 4 186 ? 93.398  129.507 67.149  1.00 59.54  ? 186 GLN E CB  1 
ATOM 6117 C CG  . GLN D 4 186 ? 93.776  128.078 66.812  1.00 65.21  ? 186 GLN E CG  1 
ATOM 6118 C CD  . GLN D 4 186 ? 93.428  127.706 65.388  1.00 69.23  ? 186 GLN E CD  1 
ATOM 6119 O OE1 . GLN D 4 186 ? 92.653  128.395 64.726  1.00 70.10  ? 186 GLN E OE1 1 
ATOM 6120 N NE2 . GLN D 4 186 ? 94.005  126.612 64.906  1.00 67.52  ? 186 GLN E NE2 1 
ATOM 6121 N N   . LEU D 4 187 ? 95.631  128.595 69.380  1.00 49.55  ? 187 LEU E N   1 
ATOM 6122 C CA  . LEU D 4 187 ? 97.023  128.252 69.615  1.00 44.46  ? 187 LEU E CA  1 
ATOM 6123 C C   . LEU D 4 187 ? 97.658  127.767 68.320  1.00 46.40  ? 187 LEU E C   1 
ATOM 6124 O O   . LEU D 4 187 ? 97.115  126.893 67.639  1.00 55.59  ? 187 LEU E O   1 
ATOM 6125 C CB  . LEU D 4 187 ? 97.122  127.176 70.691  1.00 44.15  ? 187 LEU E CB  1 
ATOM 6126 C CG  . LEU D 4 187 ? 98.524  126.720 71.076  1.00 40.18  ? 187 LEU E CG  1 
ATOM 6127 C CD1 . LEU D 4 187 ? 99.270  127.851 71.748  1.00 45.96  ? 187 LEU E CD1 1 
ATOM 6128 C CD2 . LEU D 4 187 ? 98.461  125.506 71.971  1.00 38.82  ? 187 LEU E CD2 1 
ATOM 6129 N N   . LEU D 4 188 ? 98.815  128.327 67.981  1.00 45.38  ? 188 LEU E N   1 
ATOM 6130 C CA  . LEU D 4 188 ? 99.595  127.862 66.844  1.00 50.63  ? 188 LEU E CA  1 
ATOM 6131 C C   . LEU D 4 188 ? 100.834 127.099 67.289  1.00 47.05  ? 188 LEU E C   1 
ATOM 6132 O O   . LEU D 4 188 ? 101.028 125.943 66.908  1.00 57.32  ? 188 LEU E O   1 
ATOM 6133 C CB  . LEU D 4 188 ? 100.002 129.046 65.957  1.00 52.01  ? 188 LEU E CB  1 
ATOM 6134 C CG  . LEU D 4 188 ? 98.908  129.934 65.370  1.00 51.74  ? 188 LEU E CG  1 
ATOM 6135 C CD1 . LEU D 4 188 ? 99.540  131.046 64.566  1.00 52.45  ? 188 LEU E CD1 1 
ATOM 6136 C CD2 . LEU D 4 188 ? 97.962  129.127 64.507  1.00 53.08  ? 188 LEU E CD2 1 
ATOM 6137 N N   . ILE D 4 189 ? 101.679 127.725 68.099  1.00 43.02  ? 189 ILE E N   1 
ATOM 6138 C CA  . ILE D 4 189 ? 102.949 127.158 68.527  1.00 49.10  ? 189 ILE E CA  1 
ATOM 6139 C C   . ILE D 4 189 ? 103.018 127.242 70.042  1.00 46.94  ? 189 ILE E C   1 
ATOM 6140 O O   . ILE D 4 189 ? 102.757 128.303 70.617  1.00 55.25  ? 189 ILE E O   1 
ATOM 6141 C CB  . ILE D 4 189 ? 104.144 127.890 67.890  1.00 52.32  ? 189 ILE E CB  1 
ATOM 6142 C CG1 . ILE D 4 189 ? 104.091 127.787 66.365  1.00 46.40  ? 189 ILE E CG1 1 
ATOM 6143 C CG2 . ILE D 4 189 ? 105.450 127.330 68.415  1.00 50.34  ? 189 ILE E CG2 1 
ATOM 6144 C CD1 . ILE D 4 189 ? 104.250 126.383 65.839  1.00 49.02  ? 189 ILE E CD1 1 
ATOM 6145 N N   . TYR D 4 190 ? 103.341 126.127 70.688  1.00 45.37  ? 190 TYR E N   1 
ATOM 6146 C CA  . TYR D 4 190 ? 103.519 126.095 72.130  1.00 49.03  ? 190 TYR E CA  1 
ATOM 6147 C C   . TYR D 4 190 ? 104.945 125.678 72.460  1.00 50.11  ? 190 TYR E C   1 
ATOM 6148 O O   . TYR D 4 190 ? 105.495 124.765 71.839  1.00 60.89  ? 190 TYR E O   1 
ATOM 6149 C CB  . TYR D 4 190 ? 102.506 125.157 72.806  1.00 49.83  ? 190 TYR E CB  1 
ATOM 6150 C CG  . TYR D 4 190 ? 102.585 123.703 72.409  1.00 45.49  ? 190 TYR E CG  1 
ATOM 6151 C CD1 . TYR D 4 190 ? 101.912 123.231 71.293  1.00 47.17  ? 190 TYR E CD1 1 
ATOM 6152 C CD2 . TYR D 4 190 ? 103.320 122.799 73.159  1.00 49.76  ? 190 TYR E CD2 1 
ATOM 6153 C CE1 . TYR D 4 190 ? 101.976 121.904 70.932  1.00 52.43  ? 190 TYR E CE1 1 
ATOM 6154 C CE2 . TYR D 4 190 ? 103.390 121.471 72.804  1.00 50.98  ? 190 TYR E CE2 1 
ATOM 6155 C CZ  . TYR D 4 190 ? 102.717 121.028 71.691  1.00 53.59  ? 190 TYR E CZ  1 
ATOM 6156 O OH  . TYR D 4 190 ? 102.785 119.703 71.336  1.00 52.35  ? 190 TYR E OH  1 
ATOM 6157 N N   . ARG D 4 191 ? 105.535 126.363 73.441  1.00 42.68  ? 191 ARG E N   1 
ATOM 6158 C CA  . ARG D 4 191 ? 106.945 126.202 73.806  1.00 45.70  ? 191 ARG E CA  1 
ATOM 6159 C C   . ARG D 4 191 ? 107.874 126.418 72.611  1.00 49.33  ? 191 ARG E C   1 
ATOM 6160 O O   . ARG D 4 191 ? 108.849 125.691 72.415  1.00 48.78  ? 191 ARG E O   1 
ATOM 6161 C CB  . ARG D 4 191 ? 107.195 124.847 74.468  1.00 48.59  ? 191 ARG E CB  1 
ATOM 6162 C CG  . ARG D 4 191 ? 106.698 124.791 75.900  1.00 39.57  ? 191 ARG E CG  1 
ATOM 6163 C CD  . ARG D 4 191 ? 107.068 123.489 76.565  1.00 43.94  ? 191 ARG E CD  1 
ATOM 6164 N NE  . ARG D 4 191 ? 106.358 122.358 75.984  1.00 48.27  ? 191 ARG E NE  1 
ATOM 6165 C CZ  . ARG D 4 191 ? 105.182 121.920 76.405  1.00 46.13  ? 191 ARG E CZ  1 
ATOM 6166 N NH1 . ARG D 4 191 ? 104.548 122.499 77.410  1.00 42.08  ? 191 ARG E NH1 1 
ATOM 6167 N NH2 . ARG D 4 191 ? 104.629 120.872 75.806  1.00 44.98  ? 191 ARG E NH2 1 
ATOM 6168 N N   . MET D 4 192 ? 107.536 127.415 71.793  1.00 64.35  ? 192 MET E N   1 
ATOM 6169 C CA  . MET D 4 192 ? 108.417 128.071 70.829  1.00 63.70  ? 192 MET E CA  1 
ATOM 6170 C C   . MET D 4 192 ? 108.733 127.238 69.591  1.00 64.05  ? 192 MET E C   1 
ATOM 6171 O O   . MET D 4 192 ? 109.165 127.788 68.574  1.00 64.14  ? 192 MET E O   1 
ATOM 6172 C CB  . MET D 4 192 ? 109.720 128.476 71.533  1.00 63.39  ? 192 MET E CB  1 
ATOM 6173 C CG  . MET D 4 192 ? 110.661 129.367 70.733  1.00 66.52  ? 192 MET E CG  1 
ATOM 6174 S SD  . MET D 4 192 ? 111.901 128.456 69.789  1.00 84.85  ? 192 MET E SD  1 
ATOM 6175 C CE  . MET D 4 192 ? 112.746 127.559 71.083  1.00 59.53  ? 192 MET E CE  1 
ATOM 6176 N N   . SER D 4 193 ? 108.475 125.936 69.623  1.00 59.11  ? 193 SER E N   1 
ATOM 6177 C CA  . SER D 4 193 ? 108.753 125.127 68.439  1.00 59.09  ? 193 SER E CA  1 
ATOM 6178 C C   . SER D 4 193 ? 107.662 124.127 68.088  1.00 61.03  ? 193 SER E C   1 
ATOM 6179 O O   . SER D 4 193 ? 107.517 123.800 66.906  1.00 60.72  ? 193 SER E O   1 
ATOM 6180 C CB  . SER D 4 193 ? 110.083 124.377 68.596  1.00 58.84  ? 193 SER E CB  1 
ATOM 6181 O OG  . SER D 4 193 ? 110.061 123.515 69.717  1.00 63.39  ? 193 SER E OG  1 
ATOM 6182 N N   . ASN D 4 194 ? 106.892 123.633 69.050  1.00 53.35  ? 194 ASN E N   1 
ATOM 6183 C CA  . ASN D 4 194 ? 105.943 122.566 68.787  1.00 48.86  ? 194 ASN E CA  1 
ATOM 6184 C C   . ASN D 4 194 ? 104.694 123.113 68.113  1.00 56.14  ? 194 ASN E C   1 
ATOM 6185 O O   . ASN D 4 194 ? 104.217 124.201 68.445  1.00 59.05  ? 194 ASN E O   1 
ATOM 6186 C CB  . ASN D 4 194 ? 105.581 121.855 70.087  1.00 50.81  ? 194 ASN E CB  1 
ATOM 6187 C CG  . ASN D 4 194 ? 106.802 121.391 70.850  1.00 58.15  ? 194 ASN E CG  1 
ATOM 6188 O OD1 . ASN D 4 194 ? 107.332 120.311 70.601  1.00 58.27  ? 194 ASN E OD1 1 
ATOM 6189 N ND2 . ASN D 4 194 ? 107.258 122.211 71.787  1.00 55.51  ? 194 ASN E ND2 1 
ATOM 6190 N N   . LEU D 4 195 ? 104.154 122.342 67.176  1.00 54.66  ? 195 LEU E N   1 
ATOM 6191 C CA  . LEU D 4 195 ? 102.985 122.752 66.415  1.00 52.71  ? 195 LEU E CA  1 
ATOM 6192 C C   . LEU D 4 195 ? 101.729 122.195 67.071  1.00 55.26  ? 195 LEU E C   1 
ATOM 6193 O O   . LEU D 4 195 ? 101.645 120.994 67.346  1.00 58.31  ? 195 LEU E O   1 
ATOM 6194 C CB  . LEU D 4 195 ? 103.093 122.264 64.971  1.00 60.42  ? 195 LEU E CB  1 
ATOM 6195 C CG  . LEU D 4 195 ? 102.012 122.728 63.997  1.00 63.60  ? 195 LEU E CG  1 
ATOM 6196 C CD1 . LEU D 4 195 ? 102.163 124.207 63.706  1.00 60.05  ? 195 LEU E CD1 1 
ATOM 6197 C CD2 . LEU D 4 195 ? 102.069 121.916 62.719  1.00 59.27  ? 195 LEU E CD2 1 
ATOM 6198 N N   . ALA D 4 196 ? 100.762 123.071 67.327  1.00 54.03  ? 196 ALA E N   1 
ATOM 6199 C CA  . ALA D 4 196 ? 99.548  122.668 68.018  1.00 54.45  ? 196 ALA E CA  1 
ATOM 6200 C C   . ALA D 4 196 ? 98.690  121.771 67.135  1.00 55.91  ? 196 ALA E C   1 
ATOM 6201 O O   . ALA D 4 196 ? 98.742  121.836 65.905  1.00 58.27  ? 196 ALA E O   1 
ATOM 6202 C CB  . ALA D 4 196 ? 98.748  123.894 68.453  1.00 55.81  ? 196 ALA E CB  1 
ATOM 6203 N N   . SER D 4 197 ? 97.901  120.918 67.784  1.00 63.56  ? 197 SER E N   1 
ATOM 6204 C CA  . SER D 4 197 ? 97.026  120.001 67.069  1.00 62.59  ? 197 SER E CA  1 
ATOM 6205 C C   . SER D 4 197 ? 95.976  120.766 66.275  1.00 64.24  ? 197 SER E C   1 
ATOM 6206 O O   . SER D 4 197 ? 95.348  121.698 66.786  1.00 67.08  ? 197 SER E O   1 
ATOM 6207 C CB  . SER D 4 197 ? 96.354  119.045 68.052  1.00 63.51  ? 197 SER E CB  1 
ATOM 6208 O OG  . SER D 4 197 ? 95.513  118.128 67.378  1.00 65.67  ? 197 SER E OG  1 
ATOM 6209 N N   . GLY D 4 198 ? 95.782  120.365 65.021  1.00 61.20  ? 198 GLY E N   1 
ATOM 6210 C CA  . GLY D 4 198 ? 94.834  121.027 64.150  1.00 63.28  ? 198 GLY E CA  1 
ATOM 6211 C C   . GLY D 4 198 ? 95.365  122.243 63.430  1.00 67.61  ? 198 GLY E C   1 
ATOM 6212 O O   . GLY D 4 198 ? 94.588  122.941 62.770  1.00 66.29  ? 198 GLY E O   1 
ATOM 6213 N N   . VAL D 4 199 ? 96.655  122.520 63.535  1.00 71.48  ? 199 VAL E N   1 
ATOM 6214 C CA  . VAL D 4 199 ? 97.278  123.677 62.899  1.00 68.50  ? 199 VAL E CA  1 
ATOM 6215 C C   . VAL D 4 199 ? 98.060  123.184 61.686  1.00 71.22  ? 199 VAL E C   1 
ATOM 6216 O O   . VAL D 4 199 ? 98.782  122.184 61.800  1.00 72.01  ? 199 VAL E O   1 
ATOM 6217 C CB  . VAL D 4 199 ? 98.198  124.430 63.876  1.00 65.70  ? 199 VAL E CB  1 
ATOM 6218 C CG1 . VAL D 4 199 ? 98.819  125.641 63.206  1.00 65.41  ? 199 VAL E CG1 1 
ATOM 6219 C CG2 . VAL D 4 199 ? 97.415  124.849 65.106  1.00 64.80  ? 199 VAL E CG2 1 
ATOM 6220 N N   . PRO D 4 200 ? 97.930  123.825 60.525  1.00 78.96  ? 200 PRO E N   1 
ATOM 6221 C CA  . PRO D 4 200 ? 98.653  123.353 59.339  1.00 78.87  ? 200 PRO E CA  1 
ATOM 6222 C C   . PRO D 4 200 ? 100.159 123.401 59.540  1.00 78.18  ? 200 PRO E C   1 
ATOM 6223 O O   . PRO D 4 200 ? 100.688 124.244 60.267  1.00 78.19  ? 200 PRO E O   1 
ATOM 6224 C CB  . PRO D 4 200 ? 98.208  124.327 58.242  1.00 77.65  ? 200 PRO E CB  1 
ATOM 6225 C CG  . PRO D 4 200 ? 96.900  124.853 58.715  1.00 74.41  ? 200 PRO E CG  1 
ATOM 6226 C CD  . PRO D 4 200 ? 97.009  124.928 60.206  1.00 72.28  ? 200 PRO E CD  1 
ATOM 6227 N N   . ASP D 4 201 ? 100.852 122.473 58.880  1.00 83.18  ? 201 ASP E N   1 
ATOM 6228 C CA  . ASP D 4 201 ? 102.296 122.352 59.038  1.00 83.30  ? 201 ASP E CA  1 
ATOM 6229 C C   . ASP D 4 201 ? 103.060 123.534 58.457  1.00 85.75  ? 201 ASP E C   1 
ATOM 6230 O O   . ASP D 4 201 ? 104.264 123.648 58.707  1.00 85.28  ? 201 ASP E O   1 
ATOM 6231 C CB  . ASP D 4 201 ? 102.787 121.052 58.399  1.00 84.34  ? 201 ASP E CB  1 
ATOM 6232 C CG  . ASP D 4 201 ? 102.310 120.887 56.970  1.00 87.91  ? 201 ASP E CG  1 
ATOM 6233 O OD1 . ASP D 4 201 ? 101.535 121.743 56.495  1.00 86.07  ? 201 ASP E OD1 1 
ATOM 6234 O OD2 . ASP D 4 201 ? 102.711 119.899 56.320  1.00 87.10  ? 201 ASP E OD2 1 
ATOM 6235 N N   . ARG D 4 202 ? 102.402 124.402 57.683  1.00 91.15  ? 202 ARG E N   1 
ATOM 6236 C CA  . ARG D 4 202 ? 103.097 125.552 57.114  1.00 88.45  ? 202 ARG E CA  1 
ATOM 6237 C C   . ARG D 4 202 ? 103.568 126.516 58.195  1.00 89.25  ? 202 ARG E C   1 
ATOM 6238 O O   . ARG D 4 202 ? 104.578 127.204 58.011  1.00 88.73  ? 202 ARG E O   1 
ATOM 6239 C CB  . ARG D 4 202 ? 102.197 126.269 56.107  1.00 86.02  ? 202 ARG E CB  1 
ATOM 6240 C CG  . ARG D 4 202 ? 100.895 126.810 56.674  1.00 89.55  ? 202 ARG E CG  1 
ATOM 6241 C CD  . ARG D 4 202 ? 100.091 127.511 55.588  1.00 90.56  ? 202 ARG E CD  1 
ATOM 6242 N NE  . ARG D 4 202 ? 98.890  128.158 56.101  1.00 91.10  ? 202 ARG E NE  1 
ATOM 6243 C CZ  . ARG D 4 202 ? 97.678  127.623 56.069  1.00 91.04  ? 202 ARG E CZ  1 
ATOM 6244 N NH1 . ARG D 4 202 ? 97.465  126.424 55.554  1.00 88.29  ? 202 ARG E NH1 1 
ATOM 6245 N NH2 . ARG D 4 202 ? 96.653  128.309 56.565  1.00 91.70  ? 202 ARG E NH2 1 
ATOM 6246 N N   . PHE D 4 203 ? 102.855 126.585 59.316  1.00 84.17  ? 203 PHE E N   1 
ATOM 6247 C CA  . PHE D 4 203 ? 103.316 127.372 60.451  1.00 79.20  ? 203 PHE E CA  1 
ATOM 6248 C C   . PHE D 4 203 ? 104.506 126.693 61.113  1.00 76.45  ? 203 PHE E C   1 
ATOM 6249 O O   . PHE D 4 203 ? 104.488 125.483 61.354  1.00 79.50  ? 203 PHE E O   1 
ATOM 6250 C CB  . PHE D 4 203 ? 102.188 127.557 61.463  1.00 79.32  ? 203 PHE E CB  1 
ATOM 6251 C CG  . PHE D 4 203 ? 101.062 128.412 60.968  1.00 80.47  ? 203 PHE E CG  1 
ATOM 6252 C CD1 . PHE D 4 203 ? 100.006 127.853 60.273  1.00 79.92  ? 203 PHE E CD1 1 
ATOM 6253 C CD2 . PHE D 4 203 ? 101.055 129.773 61.205  1.00 80.16  ? 203 PHE E CD2 1 
ATOM 6254 C CE1 . PHE D 4 203 ? 98.967  128.636 59.822  1.00 78.17  ? 203 PHE E CE1 1 
ATOM 6255 C CE2 . PHE D 4 203 ? 100.018 130.562 60.756  1.00 78.52  ? 203 PHE E CE2 1 
ATOM 6256 C CZ  . PHE D 4 203 ? 98.973  129.992 60.063  1.00 78.76  ? 203 PHE E CZ  1 
ATOM 6257 N N   . SER D 4 204 ? 105.542 127.471 61.408  1.00 76.38  ? 204 SER E N   1 
ATOM 6258 C CA  . SER D 4 204 ? 106.718 126.958 62.093  1.00 82.77  ? 204 SER E CA  1 
ATOM 6259 C C   . SER D 4 204 ? 107.239 128.021 63.045  1.00 82.17  ? 204 SER E C   1 
ATOM 6260 O O   . SER D 4 204 ? 107.301 129.201 62.694  1.00 82.66  ? 204 SER E O   1 
ATOM 6261 C CB  . SER D 4 204 ? 107.819 126.548 61.107  1.00 81.78  ? 204 SER E CB  1 
ATOM 6262 O OG  . SER D 4 204 ? 108.275 127.656 60.353  1.00 84.46  ? 204 SER E OG  1 
ATOM 6263 N N   . GLY D 4 205 ? 107.596 127.600 64.255  1.00 70.05  ? 205 GLY E N   1 
ATOM 6264 C CA  . GLY D 4 205 ? 108.131 128.492 65.265  1.00 69.09  ? 205 GLY E CA  1 
ATOM 6265 C C   . GLY D 4 205 ? 109.614 128.230 65.476  1.00 75.38  ? 205 GLY E C   1 
ATOM 6266 O O   . GLY D 4 205 ? 110.024 127.096 65.732  1.00 76.97  ? 205 GLY E O   1 
ATOM 6267 N N   . SER D 4 206 ? 110.403 129.293 65.359  1.00 77.53  ? 206 SER E N   1 
ATOM 6268 C CA  . SER D 4 206 ? 111.842 129.239 65.561  1.00 73.18  ? 206 SER E CA  1 
ATOM 6269 C C   . SER D 4 206 ? 112.249 130.385 66.471  1.00 73.21  ? 206 SER E C   1 
ATOM 6270 O O   . SER D 4 206 ? 111.715 131.492 66.362  1.00 78.26  ? 206 SER E O   1 
ATOM 6271 C CB  . SER D 4 206 ? 112.602 129.318 64.232  1.00 75.48  ? 206 SER E CB  1 
ATOM 6272 O OG  . SER D 4 206 ? 112.287 130.509 63.533  1.00 75.84  ? 206 SER E OG  1 
ATOM 6273 N N   . GLY D 4 207 ? 113.185 130.117 67.372  1.00 66.89  ? 207 GLY E N   1 
ATOM 6274 C CA  . GLY D 4 207 ? 113.639 131.154 68.279  1.00 68.61  ? 207 GLY E CA  1 
ATOM 6275 C C   . GLY D 4 207 ? 114.904 130.736 68.989  1.00 69.27  ? 207 GLY E C   1 
ATOM 6276 O O   . GLY D 4 207 ? 115.357 129.593 68.885  1.00 71.60  ? 207 GLY E O   1 
ATOM 6277 N N   . SER D 4 208 ? 115.470 131.694 69.719  1.00 70.97  ? 208 SER E N   1 
ATOM 6278 C CA  . SER D 4 208 ? 116.616 131.434 70.578  1.00 74.38  ? 208 SER E CA  1 
ATOM 6279 C C   . SER D 4 208 ? 116.690 132.538 71.620  1.00 77.50  ? 208 SER E C   1 
ATOM 6280 O O   . SER D 4 208 ? 116.619 133.720 71.274  1.00 76.25  ? 208 SER E O   1 
ATOM 6281 C CB  . SER D 4 208 ? 117.916 131.371 69.770  1.00 74.50  ? 208 SER E CB  1 
ATOM 6282 O OG  . SER D 4 208 ? 119.028 131.128 70.614  1.00 75.57  ? 208 SER E OG  1 
ATOM 6283 N N   . GLY D 4 209 ? 116.841 132.149 72.884  1.00 73.49  ? 209 GLY E N   1 
ATOM 6284 C CA  . GLY D 4 209 ? 117.018 133.110 73.953  1.00 72.53  ? 209 GLY E CA  1 
ATOM 6285 C C   . GLY D 4 209 ? 115.857 134.067 74.112  1.00 72.71  ? 209 GLY E C   1 
ATOM 6286 O O   . GLY D 4 209 ? 114.809 133.695 74.647  1.00 74.25  ? 209 GLY E O   1 
ATOM 6287 N N   . THR D 4 210 ? 116.039 135.314 73.674  1.00 63.63  ? 210 THR E N   1 
ATOM 6288 C CA  . THR D 4 210 ? 115.015 136.338 73.803  1.00 63.13  ? 210 THR E CA  1 
ATOM 6289 C C   . THR D 4 210 ? 114.374 136.735 72.481  1.00 61.20  ? 210 THR E C   1 
ATOM 6290 O O   . THR D 4 210 ? 113.419 137.517 72.491  1.00 66.34  ? 210 THR E O   1 
ATOM 6291 C CB  . THR D 4 210 ? 115.597 137.593 74.469  1.00 67.71  ? 210 THR E CB  1 
ATOM 6292 O OG1 . THR D 4 210 ? 116.536 138.215 73.584  1.00 69.63  ? 210 THR E OG1 1 
ATOM 6293 C CG2 . THR D 4 210 ? 116.306 137.224 75.761  1.00 64.31  ? 210 THR E CG2 1 
ATOM 6294 N N   . ALA D 4 211 ? 114.870 136.239 71.352  1.00 65.19  ? 211 ALA E N   1 
ATOM 6295 C CA  . ALA D 4 211 ? 114.358 136.603 70.037  1.00 70.27  ? 211 ALA E CA  1 
ATOM 6296 C C   . ALA D 4 211 ? 113.726 135.385 69.381  1.00 72.47  ? 211 ALA E C   1 
ATOM 6297 O O   . ALA D 4 211 ? 114.352 134.323 69.304  1.00 74.55  ? 211 ALA E O   1 
ATOM 6298 C CB  . ALA D 4 211 ? 115.470 137.166 69.151  1.00 68.69  ? 211 ALA E CB  1 
ATOM 6299 N N   . PHE D 4 212 ? 112.490 135.541 68.910  1.00 67.01  ? 212 PHE E N   1 
ATOM 6300 C CA  . PHE D 4 212 ? 111.721 134.441 68.348  1.00 65.08  ? 212 PHE E CA  1 
ATOM 6301 C C   . PHE D 4 212 ? 111.056 134.881 67.053  1.00 65.39  ? 212 PHE E C   1 
ATOM 6302 O O   . PHE D 4 212 ? 110.707 136.051 66.883  1.00 68.13  ? 212 PHE E O   1 
ATOM 6303 C CB  . PHE D 4 212 ? 110.662 133.943 69.326  1.00 63.83  ? 212 PHE E CB  1 
ATOM 6304 C CG  . PHE D 4 212 ? 111.145 133.850 70.739  1.00 63.53  ? 212 PHE E CG  1 
ATOM 6305 C CD1 . PHE D 4 212 ? 111.879 132.761 71.164  1.00 62.30  ? 212 PHE E CD1 1 
ATOM 6306 C CD2 . PHE D 4 212 ? 110.858 134.853 71.644  1.00 61.52  ? 212 PHE E CD2 1 
ATOM 6307 C CE1 . PHE D 4 212 ? 112.325 132.679 72.462  1.00 64.49  ? 212 PHE E CE1 1 
ATOM 6308 C CE2 . PHE D 4 212 ? 111.297 134.775 72.941  1.00 63.87  ? 212 PHE E CE2 1 
ATOM 6309 C CZ  . PHE D 4 212 ? 112.031 133.687 73.351  1.00 65.68  ? 212 PHE E CZ  1 
ATOM 6310 N N   . THR D 4 213 ? 110.884 133.928 66.140  1.00 71.99  ? 213 THR E N   1 
ATOM 6311 C CA  . THR D 4 213 ? 110.291 134.193 64.836  1.00 74.00  ? 213 THR E CA  1 
ATOM 6312 C C   . THR D 4 213 ? 109.231 133.146 64.532  1.00 73.46  ? 213 THR E C   1 
ATOM 6313 O O   . THR D 4 213 ? 109.461 131.949 64.732  1.00 74.36  ? 213 THR E O   1 
ATOM 6314 C CB  . THR D 4 213 ? 111.355 134.196 63.734  1.00 79.94  ? 213 THR E CB  1 
ATOM 6315 O OG1 . THR D 4 213 ? 112.421 135.082 64.097  1.00 80.38  ? 213 THR E OG1 1 
ATOM 6316 C CG2 . THR D 4 213 ? 110.751 134.658 62.418  1.00 77.03  ? 213 THR E CG2 1 
ATOM 6317 N N   . LEU D 4 214 ? 108.079 133.599 64.047  1.00 76.58  ? 214 LEU E N   1 
ATOM 6318 C CA  . LEU D 4 214 ? 107.008 132.732 63.569  1.00 76.67  ? 214 LEU E CA  1 
ATOM 6319 C C   . LEU D 4 214 ? 106.949 132.830 62.051  1.00 79.03  ? 214 LEU E C   1 
ATOM 6320 O O   . LEU D 4 214 ? 106.656 133.899 61.506  1.00 80.90  ? 214 LEU E O   1 
ATOM 6321 C CB  . LEU D 4 214 ? 105.666 133.125 64.184  1.00 76.74  ? 214 LEU E CB  1 
ATOM 6322 C CG  . LEU D 4 214 ? 104.459 132.319 63.703  1.00 73.15  ? 214 LEU E CG  1 
ATOM 6323 C CD1 . LEU D 4 214 ? 104.589 130.866 64.117  1.00 75.64  ? 214 LEU E CD1 1 
ATOM 6324 C CD2 . LEU D 4 214 ? 103.164 132.915 64.215  1.00 71.89  ? 214 LEU E CD2 1 
ATOM 6325 N N   . THR D 4 215 ? 107.221 131.720 61.373  1.00 86.70  ? 215 THR E N   1 
ATOM 6326 C CA  . THR D 4 215 ? 107.260 131.680 59.917  1.00 87.01  ? 215 THR E CA  1 
ATOM 6327 C C   . THR D 4 215 ? 105.977 131.062 59.378  1.00 87.62  ? 215 THR E C   1 
ATOM 6328 O O   . THR D 4 215 ? 105.572 129.981 59.815  1.00 89.89  ? 215 THR E O   1 
ATOM 6329 C CB  . THR D 4 215 ? 108.471 130.886 59.425  1.00 88.90  ? 215 THR E CB  1 
ATOM 6330 O OG1 . THR D 4 215 ? 109.669 131.455 59.967  1.00 88.40  ? 215 THR E OG1 1 
ATOM 6331 C CG2 . THR D 4 215 ? 108.547 130.919 57.908  1.00 86.13  ? 215 THR E CG2 1 
ATOM 6332 N N   . ILE D 4 216 ? 105.345 131.752 58.431  1.00 95.80  ? 216 ILE E N   1 
ATOM 6333 C CA  . ILE D 4 216 ? 104.100 131.308 57.813  1.00 95.97  ? 216 ILE E CA  1 
ATOM 6334 C C   . ILE D 4 216 ? 104.380 131.123 56.327  1.00 98.78  ? 216 ILE E C   1 
ATOM 6335 O O   . ILE D 4 216 ? 104.366 132.091 55.559  1.00 99.20  ? 216 ILE E O   1 
ATOM 6336 C CB  . ILE D 4 216 ? 102.958 132.304 58.038  1.00 96.46  ? 216 ILE E CB  1 
ATOM 6337 C CG1 . ILE D 4 216 ? 102.827 132.642 59.522  1.00 95.60  ? 216 ILE E CG1 1 
ATOM 6338 C CG2 . ILE D 4 216 ? 101.653 131.744 57.500  1.00 97.81  ? 216 ILE E CG2 1 
ATOM 6339 C CD1 . ILE D 4 216 ? 101.812 133.720 59.805  1.00 94.72  ? 216 ILE E CD1 1 
ATOM 6340 N N   . SER D 4 217 ? 104.636 129.885 55.915  1.00 108.54 ? 217 SER E N   1 
ATOM 6341 C CA  . SER D 4 217 ? 104.884 129.590 54.511  1.00 106.81 ? 217 SER E CA  1 
ATOM 6342 C C   . SER D 4 217 ? 103.568 129.447 53.758  1.00 107.17 ? 217 SER E C   1 
ATOM 6343 O O   . SER D 4 217 ? 102.616 128.844 54.259  1.00 110.90 ? 217 SER E O   1 
ATOM 6344 C CB  . SER D 4 217 ? 105.708 128.311 54.373  1.00 105.53 ? 217 SER E CB  1 
ATOM 6345 O OG  . SER D 4 217 ? 106.939 128.424 55.063  1.00 106.37 ? 217 SER E OG  1 
ATOM 6346 N N   . ARG D 4 218 ? 103.522 130.000 52.545  1.00 113.53 ? 218 ARG E N   1 
ATOM 6347 C CA  . ARG D 4 218 ? 102.343 129.923 51.679  1.00 116.77 ? 218 ARG E CA  1 
ATOM 6348 C C   . ARG D 4 218 ? 101.104 130.478 52.386  1.00 117.14 ? 218 ARG E C   1 
ATOM 6349 O O   . ARG D 4 218 ? 100.135 129.767 52.657  1.00 115.69 ? 218 ARG E O   1 
ATOM 6350 C CB  . ARG D 4 218 ? 102.104 128.488 51.193  1.00 115.46 ? 218 ARG E CB  1 
ATOM 6351 C CG  . ARG D 4 218 ? 103.245 127.901 50.376  1.00 115.79 ? 218 ARG E CG  1 
ATOM 6352 C CD  . ARG D 4 218 ? 104.104 126.963 51.208  1.00 116.32 ? 218 ARG E CD  1 
ATOM 6353 N NE  . ARG D 4 218 ? 103.345 125.812 51.683  1.00 118.31 ? 218 ARG E NE  1 
ATOM 6354 C CZ  . ARG D 4 218 ? 103.856 124.820 52.399  1.00 118.20 ? 218 ARG E CZ  1 
ATOM 6355 N NH1 . ARG D 4 218 ? 105.133 124.802 52.742  1.00 117.29 ? 218 ARG E NH1 1 
ATOM 6356 N NH2 . ARG D 4 218 ? 103.066 123.821 52.780  1.00 115.84 ? 218 ARG E NH2 1 
ATOM 6357 N N   . LEU D 4 219 ? 101.160 131.774 52.688  1.00 116.16 ? 219 LEU E N   1 
ATOM 6358 C CA  . LEU D 4 219 ? 100.078 132.426 53.412  1.00 114.98 ? 219 LEU E CA  1 
ATOM 6359 C C   . LEU D 4 219 ? 98.764  132.304 52.648  1.00 116.91 ? 219 LEU E C   1 
ATOM 6360 O O   . LEU D 4 219 ? 98.732  132.363 51.417  1.00 119.33 ? 219 LEU E O   1 
ATOM 6361 C CB  . LEU D 4 219 ? 100.421 133.898 53.649  1.00 114.06 ? 219 LEU E CB  1 
ATOM 6362 C CG  . LEU D 4 219 ? 99.383  134.765 54.367  1.00 115.36 ? 219 LEU E CG  1 
ATOM 6363 C CD1 . LEU D 4 219 ? 100.041 135.598 55.451  1.00 115.12 ? 219 LEU E CD1 1 
ATOM 6364 C CD2 . LEU D 4 219 ? 98.655  135.661 53.379  1.00 115.94 ? 219 LEU E CD2 1 
ATOM 6365 N N   . GLU D 4 220 ? 97.677  132.129 53.391  1.00 114.58 ? 220 GLU E N   1 
ATOM 6366 C CA  . GLU D 4 220 ? 96.338  131.988 52.838  1.00 112.42 ? 220 GLU E CA  1 
ATOM 6367 C C   . GLU D 4 220 ? 95.416  133.043 53.442  1.00 112.25 ? 220 GLU E C   1 
ATOM 6368 O O   . GLU D 4 220 ? 95.807  133.818 54.318  1.00 112.74 ? 220 GLU E O   1 
ATOM 6369 C CB  . GLU D 4 220 ? 95.791  130.579 53.081  1.00 110.96 ? 220 GLU E CB  1 
ATOM 6370 C CG  . GLU D 4 220 ? 96.596  129.483 52.411  1.00 110.99 ? 220 GLU E CG  1 
ATOM 6371 C CD  . GLU D 4 220 ? 95.934  128.126 52.519  1.00 113.06 ? 220 GLU E CD  1 
ATOM 6372 O OE1 . GLU D 4 220 ? 94.769  128.066 52.965  1.00 111.92 ? 220 GLU E OE1 1 
ATOM 6373 O OE2 . GLU D 4 220 ? 96.578  127.118 52.158  1.00 113.16 ? 220 GLU E OE2 1 
ATOM 6374 N N   . ALA D 4 221 ? 94.175  133.069 52.950  1.00 114.54 ? 221 ALA E N   1 
ATOM 6375 C CA  . ALA D 4 221 ? 93.209  134.053 53.428  1.00 116.03 ? 221 ALA E CA  1 
ATOM 6376 C C   . ALA D 4 221 ? 92.885  133.841 54.901  1.00 117.54 ? 221 ALA E C   1 
ATOM 6377 O O   . ALA D 4 221 ? 92.685  134.808 55.645  1.00 115.92 ? 221 ALA E O   1 
ATOM 6378 C CB  . ALA D 4 221 ? 91.937  133.991 52.584  1.00 114.39 ? 221 ALA E CB  1 
ATOM 6379 N N   . GLU D 4 222 ? 92.812  132.581 55.338  1.00 105.42 ? 222 GLU E N   1 
ATOM 6380 C CA  . GLU D 4 222 ? 92.472  132.299 56.728  1.00 104.12 ? 222 GLU E CA  1 
ATOM 6381 C C   . GLU D 4 222 ? 93.550  132.795 57.685  1.00 103.52 ? 222 GLU E C   1 
ATOM 6382 O O   . GLU D 4 222 ? 93.244  133.153 58.827  1.00 102.92 ? 222 GLU E O   1 
ATOM 6383 C CB  . GLU D 4 222 ? 92.227  130.803 56.924  1.00 103.44 ? 222 GLU E CB  1 
ATOM 6384 C CG  . GLU D 4 222 ? 93.410  129.917 56.580  1.00 105.60 ? 222 GLU E CG  1 
ATOM 6385 C CD  . GLU D 4 222 ? 93.154  128.458 56.902  1.00 106.37 ? 222 GLU E CD  1 
ATOM 6386 O OE1 . GLU D 4 222 ? 92.031  128.134 57.345  1.00 105.13 ? 222 GLU E OE1 1 
ATOM 6387 O OE2 . GLU D 4 222 ? 94.075  127.634 56.717  1.00 105.58 ? 222 GLU E OE2 1 
ATOM 6388 N N   . ASP D 4 223 ? 94.809  132.826 57.243  1.00 98.29  ? 223 ASP E N   1 
ATOM 6389 C CA  . ASP D 4 223 ? 95.904  133.249 58.107  1.00 97.13  ? 223 ASP E CA  1 
ATOM 6390 C C   . ASP D 4 223 ? 95.839  134.727 58.469  1.00 97.49  ? 223 ASP E C   1 
ATOM 6391 O O   . ASP D 4 223 ? 96.556  135.154 59.380  1.00 98.01  ? 223 ASP E O   1 
ATOM 6392 C CB  . ASP D 4 223 ? 97.247  132.943 57.442  1.00 96.33  ? 223 ASP E CB  1 
ATOM 6393 C CG  . ASP D 4 223 ? 97.431  131.467 57.157  1.00 98.35  ? 223 ASP E CG  1 
ATOM 6394 O OD1 . ASP D 4 223 ? 96.499  130.686 57.443  1.00 97.49  ? 223 ASP E OD1 1 
ATOM 6395 O OD2 . ASP D 4 223 ? 98.509  131.085 56.656  1.00 96.20  ? 223 ASP E OD2 1 
ATOM 6396 N N   . VAL D 4 224 ? 95.021  135.516 57.768  1.00 98.59  ? 224 VAL E N   1 
ATOM 6397 C CA  . VAL D 4 224 ? 94.886  136.932 58.085  1.00 99.51  ? 224 VAL E CA  1 
ATOM 6398 C C   . VAL D 4 224 ? 94.347  137.089 59.499  1.00 100.03 ? 224 VAL E C   1 
ATOM 6399 O O   . VAL D 4 224 ? 93.328  136.491 59.865  1.00 99.38  ? 224 VAL E O   1 
ATOM 6400 C CB  . VAL D 4 224 ? 93.978  137.619 57.055  1.00 97.72  ? 224 VAL E CB  1 
ATOM 6401 C CG1 . VAL D 4 224 ? 93.681  139.048 57.472  1.00 96.46  ? 224 VAL E CG1 1 
ATOM 6402 C CG2 . VAL D 4 224 ? 94.623  137.584 55.680  1.00 97.16  ? 224 VAL E CG2 1 
ATOM 6403 N N   . GLY D 4 225 ? 95.027  137.897 60.299  1.00 84.68  ? 225 GLY E N   1 
ATOM 6404 C CA  . GLY D 4 225 ? 94.603  138.141 61.660  1.00 83.17  ? 225 GLY E CA  1 
ATOM 6405 C C   . GLY D 4 225 ? 95.736  138.736 62.472  1.00 86.73  ? 225 GLY E C   1 
ATOM 6406 O O   . GLY D 4 225 ? 96.781  139.105 61.939  1.00 90.27  ? 225 GLY E O   1 
ATOM 6407 N N   . VAL D 4 226 ? 95.505  138.810 63.780  1.00 76.62  ? 226 VAL E N   1 
ATOM 6408 C CA  . VAL D 4 226 ? 96.492  139.317 64.727  1.00 74.98  ? 226 VAL E CA  1 
ATOM 6409 C C   . VAL D 4 226 ? 97.199  138.146 65.392  1.00 70.87  ? 226 VAL E C   1 
ATOM 6410 O O   . VAL D 4 226 ? 96.561  137.166 65.796  1.00 72.71  ? 226 VAL E O   1 
ATOM 6411 C CB  . VAL D 4 226 ? 95.835  140.233 65.776  1.00 66.77  ? 226 VAL E CB  1 
ATOM 6412 C CG1 . VAL D 4 226 ? 96.897  140.927 66.600  1.00 70.08  ? 226 VAL E CG1 1 
ATOM 6413 C CG2 . VAL D 4 226 ? 94.944  141.250 65.097  1.00 68.00  ? 226 VAL E CG2 1 
ATOM 6414 N N   . TYR D 4 227 ? 98.520  138.245 65.504  1.00 63.70  ? 227 TYR E N   1 
ATOM 6415 C CA  . TYR D 4 227 ? 99.342  137.207 66.109  1.00 67.81  ? 227 TYR E CA  1 
ATOM 6416 C C   . TYR D 4 227 ? 99.936  137.723 67.411  1.00 69.56  ? 227 TYR E C   1 
ATOM 6417 O O   . TYR D 4 227 ? 100.552 138.793 67.435  1.00 71.32  ? 227 TYR E O   1 
ATOM 6418 C CB  . TYR D 4 227 ? 100.459 136.772 65.157  1.00 66.87  ? 227 TYR E CB  1 
ATOM 6419 C CG  . TYR D 4 227 ? 99.963  136.079 63.909  1.00 69.31  ? 227 TYR E CG  1 
ATOM 6420 C CD1 . TYR D 4 227 ? 99.410  136.804 62.864  1.00 70.97  ? 227 TYR E CD1 1 
ATOM 6421 C CD2 . TYR D 4 227 ? 100.056 134.703 63.773  1.00 69.88  ? 227 TYR E CD2 1 
ATOM 6422 C CE1 . TYR D 4 227 ? 98.955  136.178 61.725  1.00 70.88  ? 227 TYR E CE1 1 
ATOM 6423 C CE2 . TYR D 4 227 ? 99.605  134.068 62.634  1.00 72.59  ? 227 TYR E CE2 1 
ATOM 6424 C CZ  . TYR D 4 227 ? 99.057  134.812 61.613  1.00 74.83  ? 227 TYR E CZ  1 
ATOM 6425 O OH  . TYR D 4 227 ? 98.603  134.187 60.476  1.00 76.98  ? 227 TYR E OH  1 
ATOM 6426 N N   . TYR D 4 228 ? 99.756  136.960 68.484  1.00 55.68  ? 228 TYR E N   1 
ATOM 6427 C CA  . TYR D 4 228 ? 100.256 137.316 69.803  1.00 57.23  ? 228 TYR E CA  1 
ATOM 6428 C C   . TYR D 4 228 ? 101.276 136.287 70.263  1.00 59.55  ? 228 TYR E C   1 
ATOM 6429 O O   . TYR D 4 228 ? 101.070 135.082 70.095  1.00 69.17  ? 228 TYR E O   1 
ATOM 6430 C CB  . TYR D 4 228 ? 99.121  137.401 70.824  1.00 59.39  ? 228 TYR E CB  1 
ATOM 6431 C CG  . TYR D 4 228 ? 98.068  138.430 70.498  1.00 62.81  ? 228 TYR E CG  1 
ATOM 6432 C CD1 . TYR D 4 228 ? 98.223  139.751 70.881  1.00 62.16  ? 228 TYR E CD1 1 
ATOM 6433 C CD2 . TYR D 4 228 ? 96.914  138.078 69.815  1.00 63.59  ? 228 TYR E CD2 1 
ATOM 6434 C CE1 . TYR D 4 228 ? 97.264  140.691 70.589  1.00 62.44  ? 228 TYR E CE1 1 
ATOM 6435 C CE2 . TYR D 4 228 ? 95.950  139.013 69.521  1.00 57.89  ? 228 TYR E CE2 1 
ATOM 6436 C CZ  . TYR D 4 228 ? 96.131  140.318 69.909  1.00 57.58  ? 228 TYR E CZ  1 
ATOM 6437 O OH  . TYR D 4 228 ? 95.173  141.257 69.616  1.00 60.53  ? 228 TYR E OH  1 
ATOM 6438 N N   . CYS D 4 229 ? 102.376 136.758 70.839  1.00 56.52  ? 229 CYS E N   1 
ATOM 6439 C CA  . CYS D 4 229 ? 103.341 135.890 71.498  1.00 52.68  ? 229 CYS E CA  1 
ATOM 6440 C C   . CYS D 4 229 ? 103.198 136.038 73.005  1.00 61.68  ? 229 CYS E C   1 
ATOM 6441 O O   . CYS D 4 229 ? 103.173 137.159 73.523  1.00 71.74  ? 229 CYS E O   1 
ATOM 6442 C CB  . CYS D 4 229 ? 104.776 136.202 71.064  1.00 57.91  ? 229 CYS E CB  1 
ATOM 6443 S SG  . CYS D 4 229 ? 105.325 137.915 71.243  1.00 85.07  ? 229 CYS E SG  1 
ATOM 6444 N N   . MET D 4 230 ? 103.089 134.911 73.699  1.00 47.71  ? 230 MET E N   1 
ATOM 6445 C CA  . MET D 4 230 ? 102.927 134.885 75.143  1.00 41.51  ? 230 MET E CA  1 
ATOM 6446 C C   . MET D 4 230 ? 104.064 134.088 75.762  1.00 45.72  ? 230 MET E C   1 
ATOM 6447 O O   . MET D 4 230 ? 104.535 133.108 75.178  1.00 48.31  ? 230 MET E O   1 
ATOM 6448 C CB  . MET D 4 230 ? 101.585 134.271 75.544  1.00 47.43  ? 230 MET E CB  1 
ATOM 6449 C CG  . MET D 4 230 ? 101.284 134.359 77.028  1.00 46.56  ? 230 MET E CG  1 
ATOM 6450 S SD  . MET D 4 230 ? 99.996  133.219 77.545  1.00 43.88  ? 230 MET E SD  1 
ATOM 6451 C CE  . MET D 4 230 ? 100.782 131.657 77.178  1.00 42.30  ? 230 MET E CE  1 
ATOM 6452 N N   . GLN D 4 231 ? 104.512 134.520 76.934  1.00 44.78  ? 231 GLN E N   1 
ATOM 6453 C CA  . GLN D 4 231 ? 105.515 133.803 77.705  1.00 43.85  ? 231 GLN E CA  1 
ATOM 6454 C C   . GLN D 4 231 ? 104.833 133.034 78.829  1.00 51.77  ? 231 GLN E C   1 
ATOM 6455 O O   . GLN D 4 231 ? 103.891 133.530 79.452  1.00 59.24  ? 231 GLN E O   1 
ATOM 6456 C CB  . GLN D 4 231 ? 106.567 134.763 78.265  1.00 41.17  ? 231 GLN E CB  1 
ATOM 6457 C CG  . GLN D 4 231 ? 106.035 135.807 79.222  1.00 46.40  ? 231 GLN E CG  1 
ATOM 6458 C CD  . GLN D 4 231 ? 106.067 135.345 80.663  1.00 53.31  ? 231 GLN E CD  1 
ATOM 6459 O OE1 . GLN D 4 231 ? 106.882 134.504 81.036  1.00 51.74  ? 231 GLN E OE1 1 
ATOM 6460 N NE2 . GLN D 4 231 ? 105.169 135.884 81.478  1.00 55.78  ? 231 GLN E NE2 1 
ATOM 6461 N N   . HIS D 4 232 ? 105.298 131.811 79.072  1.00 45.62  ? 232 HIS E N   1 
ATOM 6462 C CA  . HIS D 4 232 ? 104.808 131.007 80.184  1.00 40.98  ? 232 HIS E CA  1 
ATOM 6463 C C   . HIS D 4 232 ? 105.936 130.610 81.127  1.00 49.49  ? 232 HIS E C   1 
ATOM 6464 O O   . HIS D 4 232 ? 105.820 129.615 81.848  1.00 59.79  ? 232 HIS E O   1 
ATOM 6465 C CB  . HIS D 4 232 ? 104.087 129.764 79.662  1.00 39.74  ? 232 HIS E CB  1 
ATOM 6466 C CG  . HIS D 4 232 ? 102.972 129.290 80.541  1.00 47.32  ? 232 HIS E CG  1 
ATOM 6467 N ND1 . HIS D 4 232 ? 103.150 128.982 81.871  1.00 50.30  ? 232 HIS E ND1 1 
ATOM 6468 C CD2 . HIS D 4 232 ? 101.667 129.055 80.273  1.00 41.12  ? 232 HIS E CD2 1 
ATOM 6469 C CE1 . HIS D 4 232 ? 102.001 128.587 82.388  1.00 43.96  ? 232 HIS E CE1 1 
ATOM 6470 N NE2 . HIS D 4 232 ? 101.085 128.621 81.438  1.00 43.45  ? 232 HIS E NE2 1 
ATOM 6471 N N   . LEU D 4 233 ? 107.030 131.374 81.132  1.00 47.43  ? 233 LEU E N   1 
ATOM 6472 C CA  . LEU D 4 233 ? 108.143 131.080 82.027  1.00 46.70  ? 233 LEU E CA  1 
ATOM 6473 C C   . LEU D 4 233 ? 107.756 131.302 83.483  1.00 45.01  ? 233 LEU E C   1 
ATOM 6474 O O   . LEU D 4 233 ? 108.146 130.524 84.361  1.00 47.27  ? 233 LEU E O   1 
ATOM 6475 C CB  . LEU D 4 233 ? 109.353 131.932 81.651  1.00 46.71  ? 233 LEU E CB  1 
ATOM 6476 C CG  . LEU D 4 233 ? 110.612 131.708 82.489  1.00 50.42  ? 233 LEU E CG  1 
ATOM 6477 C CD1 . LEU D 4 233 ? 111.102 130.280 82.351  1.00 42.08  ? 233 LEU E CD1 1 
ATOM 6478 C CD2 . LEU D 4 233 ? 111.698 132.692 82.097  1.00 52.18  ? 233 LEU E CD2 1 
ATOM 6479 N N   . GLU D 4 234 ? 106.995 132.356 83.761  1.00 47.01  ? 234 GLU E N   1 
ATOM 6480 C CA  . GLU D 4 234 ? 106.608 132.670 85.127  1.00 48.72  ? 234 GLU E CA  1 
ATOM 6481 C C   . GLU D 4 234 ? 105.368 133.547 85.100  1.00 54.00  ? 234 GLU E C   1 
ATOM 6482 O O   . GLU D 4 234 ? 105.029 134.145 84.076  1.00 61.28  ? 234 GLU E O   1 
ATOM 6483 C CB  . GLU D 4 234 ? 107.738 133.370 85.885  1.00 54.74  ? 234 GLU E CB  1 
ATOM 6484 C CG  . GLU D 4 234 ? 108.064 134.754 85.359  1.00 54.93  ? 234 GLU E CG  1 
ATOM 6485 C CD  . GLU D 4 234 ? 109.158 135.433 86.153  1.00 62.11  ? 234 GLU E CD  1 
ATOM 6486 O OE1 . GLU D 4 234 ? 109.849 134.739 86.927  1.00 58.21  ? 234 GLU E OE1 1 
ATOM 6487 O OE2 . GLU D 4 234 ? 109.325 136.661 86.007  1.00 66.19  ? 234 GLU E OE2 1 
ATOM 6488 N N   . TYR D 4 235 ? 104.697 133.615 86.244  1.00 46.54  ? 235 TYR E N   1 
ATOM 6489 C CA  . TYR D 4 235 ? 103.528 134.470 86.388  1.00 42.23  ? 235 TYR E CA  1 
ATOM 6490 C C   . TYR D 4 235 ? 103.945 135.858 86.866  1.00 46.99  ? 235 TYR E C   1 
ATOM 6491 O O   . TYR D 4 235 ? 104.878 135.985 87.664  1.00 52.87  ? 235 TYR E O   1 
ATOM 6492 C CB  . TYR D 4 235 ? 102.529 133.860 87.365  1.00 40.89  ? 235 TYR E CB  1 
ATOM 6493 C CG  . TYR D 4 235 ? 101.804 132.664 86.797  1.00 45.80  ? 235 TYR E CG  1 
ATOM 6494 C CD1 . TYR D 4 235 ? 102.345 131.391 86.889  1.00 45.41  ? 235 TYR E CD1 1 
ATOM 6495 C CD2 . TYR D 4 235 ? 100.582 132.810 86.158  1.00 41.52  ? 235 TYR E CD2 1 
ATOM 6496 C CE1 . TYR D 4 235 ? 101.687 130.299 86.369  1.00 45.30  ? 235 TYR E CE1 1 
ATOM 6497 C CE2 . TYR D 4 235 ? 99.918  131.723 85.632  1.00 36.34  ? 235 TYR E CE2 1 
ATOM 6498 C CZ  . TYR D 4 235 ? 100.475 130.471 85.741  1.00 46.29  ? 235 TYR E CZ  1 
ATOM 6499 O OH  . TYR D 4 235 ? 99.816  129.384 85.221  1.00 40.80  ? 235 TYR E OH  1 
ATOM 6500 N N   . PRO D 4 236 ? 103.271 136.915 86.405  1.00 51.38  ? 236 PRO E N   1 
ATOM 6501 C CA  . PRO D 4 236 ? 102.080 136.918 85.547  1.00 51.67  ? 236 PRO E CA  1 
ATOM 6502 C C   . PRO D 4 236 ? 102.391 136.644 84.087  1.00 50.21  ? 236 PRO E C   1 
ATOM 6503 O O   . PRO D 4 236 ? 103.403 137.093 83.563  1.00 63.34  ? 236 PRO E O   1 
ATOM 6504 C CB  . PRO D 4 236 ? 101.535 138.336 85.741  1.00 52.38  ? 236 PRO E CB  1 
ATOM 6505 C CG  . PRO D 4 236 ? 102.763 139.160 85.951  1.00 51.73  ? 236 PRO E CG  1 
ATOM 6506 C CD  . PRO D 4 236 ? 103.697 138.283 86.747  1.00 52.72  ? 236 PRO E CD  1 
ATOM 6507 N N   . LEU D 4 237 ? 101.529 135.893 83.411  1.00 37.12  ? 237 LEU E N   1 
ATOM 6508 C CA  . LEU D 4 237 ? 101.707 135.656 81.988  1.00 41.22  ? 237 LEU E CA  1 
ATOM 6509 C C   . LEU D 4 237 ? 101.468 136.951 81.227  1.00 50.86  ? 237 LEU E C   1 
ATOM 6510 O O   . LEU D 4 237 ? 100.457 137.627 81.434  1.00 58.88  ? 237 LEU E O   1 
ATOM 6511 C CB  . LEU D 4 237 ? 100.751 134.565 81.513  1.00 40.85  ? 237 LEU E CB  1 
ATOM 6512 C CG  . LEU D 4 237 ? 100.752 133.286 82.351  1.00 36.08  ? 237 LEU E CG  1 
ATOM 6513 C CD1 . LEU D 4 237 ? 99.753  132.305 81.800  1.00 40.21  ? 237 LEU E CD1 1 
ATOM 6514 C CD2 . LEU D 4 237 ? 102.128 132.668 82.391  1.00 43.06  ? 237 LEU E CD2 1 
ATOM 6515 N N   . THR D 4 238 ? 102.400 137.302 80.350  1.00 50.58  ? 238 THR E N   1 
ATOM 6516 C CA  . THR D 4 238 ? 102.345 138.557 79.619  1.00 45.03  ? 238 THR E CA  1 
ATOM 6517 C C   . THR D 4 238 ? 102.310 138.290 78.124  1.00 51.36  ? 238 THR E C   1 
ATOM 6518 O O   . THR D 4 238 ? 102.936 137.345 77.635  1.00 61.94  ? 238 THR E O   1 
ATOM 6519 C CB  . THR D 4 238 ? 103.539 139.450 79.955  1.00 50.09  ? 238 THR E CB  1 
ATOM 6520 O OG1 . THR D 4 238 ? 104.754 138.762 79.635  1.00 54.09  ? 238 THR E OG1 1 
ATOM 6521 C CG2 . THR D 4 238 ? 103.539 139.805 81.430  1.00 54.52  ? 238 THR E CG2 1 
ATOM 6522 N N   . PHE D 4 239 ? 101.568 139.127 77.410  1.00 51.96  ? 239 PHE E N   1 
ATOM 6523 C CA  . PHE D 4 239 ? 101.401 139.028 75.970  1.00 53.80  ? 239 PHE E CA  1 
ATOM 6524 C C   . PHE D 4 239 ? 102.176 140.136 75.271  1.00 56.26  ? 239 PHE E C   1 
ATOM 6525 O O   . PHE D 4 239 ? 102.444 141.192 75.850  1.00 50.23  ? 239 PHE E O   1 
ATOM 6526 C CB  . PHE D 4 239 ? 99.924  139.102 75.583  1.00 51.82  ? 239 PHE E CB  1 
ATOM 6527 C CG  . PHE D 4 239 ? 99.140  137.888 75.963  1.00 48.26  ? 239 PHE E CG  1 
ATOM 6528 C CD1 . PHE D 4 239 ? 98.602  137.765 77.227  1.00 53.00  ? 239 PHE E CD1 1 
ATOM 6529 C CD2 . PHE D 4 239 ? 98.938  136.870 75.054  1.00 50.62  ? 239 PHE E CD2 1 
ATOM 6530 C CE1 . PHE D 4 239 ? 97.883  136.650 77.578  1.00 53.88  ? 239 PHE E CE1 1 
ATOM 6531 C CE2 . PHE D 4 239 ? 98.220  135.754 75.401  1.00 51.83  ? 239 PHE E CE2 1 
ATOM 6532 C CZ  . PHE D 4 239 ? 97.690  135.644 76.664  1.00 53.22  ? 239 PHE E CZ  1 
ATOM 6533 N N   . GLY D 4 240 ? 102.546 139.878 74.023  1.00 59.45  ? 240 GLY E N   1 
ATOM 6534 C CA  . GLY D 4 240 ? 103.069 140.926 73.181  1.00 57.12  ? 240 GLY E CA  1 
ATOM 6535 C C   . GLY D 4 240 ? 101.974 141.850 72.691  1.00 59.21  ? 240 GLY E C   1 
ATOM 6536 O O   . GLY D 4 240 ? 100.784 141.584 72.849  1.00 59.24  ? 240 GLY E O   1 
ATOM 6537 N N   . ALA D 4 241 ? 102.399 142.963 72.090  1.00 61.13  ? 241 ALA E N   1 
ATOM 6538 C CA  . ALA D 4 241 ? 101.442 143.933 71.568  1.00 59.72  ? 241 ALA E CA  1 
ATOM 6539 C C   . ALA D 4 241 ? 100.558 143.314 70.495  1.00 61.03  ? 241 ALA E C   1 
ATOM 6540 O O   . ALA D 4 241 ? 99.355  143.593 70.433  1.00 64.28  ? 241 ALA E O   1 
ATOM 6541 C CB  . ALA D 4 241 ? 102.177 145.154 71.019  1.00 60.56  ? 241 ALA E CB  1 
ATOM 6542 N N   . GLY D 4 242 ? 101.131 142.479 69.647  1.00 69.33  ? 242 GLY E N   1 
ATOM 6543 C CA  . GLY D 4 242 ? 100.404 141.814 68.582  1.00 66.34  ? 242 GLY E CA  1 
ATOM 6544 C C   . GLY D 4 242 ? 100.808 142.360 67.226  1.00 73.47  ? 242 GLY E C   1 
ATOM 6545 O O   . GLY D 4 242 ? 101.005 143.568 67.050  1.00 76.02  ? 242 GLY E O   1 
ATOM 6546 N N   . THR D 4 243 ? 100.934 141.461 66.255  1.00 80.29  ? 243 THR E N   1 
ATOM 6547 C CA  . THR D 4 243 ? 101.254 141.816 64.880  1.00 77.44  ? 243 THR E CA  1 
ATOM 6548 C C   . THR D 4 243 ? 100.070 141.460 63.994  1.00 78.95  ? 243 THR E C   1 
ATOM 6549 O O   . THR D 4 243 ? 99.658  140.297 63.941  1.00 82.90  ? 243 THR E O   1 
ATOM 6550 C CB  . THR D 4 243 ? 102.513 141.092 64.407  1.00 79.85  ? 243 THR E CB  1 
ATOM 6551 O OG1 . THR D 4 243 ? 103.621 141.474 65.230  1.00 81.98  ? 243 THR E OG1 1 
ATOM 6552 C CG2 . THR D 4 243 ? 102.817 141.439 62.960  1.00 83.50  ? 243 THR E CG2 1 
ATOM 6553 N N   . LYS D 4 244 ? 99.530  142.456 63.300  1.00 90.74  ? 244 LYS E N   1 
ATOM 6554 C CA  . LYS D 4 244 ? 98.367  142.273 62.445  1.00 93.24  ? 244 LYS E CA  1 
ATOM 6555 C C   . LYS D 4 244 ? 98.823  142.050 61.010  1.00 96.46  ? 244 LYS E C   1 
ATOM 6556 O O   . LYS D 4 244 ? 99.696  142.767 60.513  1.00 100.29 ? 244 LYS E O   1 
ATOM 6557 C CB  . LYS D 4 244 ? 97.440  143.486 62.524  1.00 94.44  ? 244 LYS E CB  1 
ATOM 6558 C CG  . LYS D 4 244 ? 96.200  143.381 61.655  1.00 96.34  ? 244 LYS E CG  1 
ATOM 6559 C CD  . LYS D 4 244 ? 95.341  144.627 61.780  1.00 96.07  ? 244 LYS E CD  1 
ATOM 6560 C CE  . LYS D 4 244 ? 94.113  144.541 60.892  1.00 95.65  ? 244 LYS E CE  1 
ATOM 6561 N NZ  . LYS D 4 244 ? 93.278  145.769 60.987  1.00 94.56  ? 244 LYS E NZ  1 
ATOM 6562 N N   . LEU D 4 245 ? 98.234  141.057 60.350  1.00 103.78 ? 245 LEU E N   1 
ATOM 6563 C CA  . LEU D 4 245 ? 98.468  140.804 58.936  1.00 105.06 ? 245 LEU E CA  1 
ATOM 6564 C C   . LEU D 4 245 ? 97.254  141.258 58.139  1.00 105.66 ? 245 LEU E C   1 
ATOM 6565 O O   . LEU D 4 245 ? 96.124  140.870 58.448  1.00 106.76 ? 245 LEU E O   1 
ATOM 6566 C CB  . LEU D 4 245 ? 98.747  139.323 58.675  1.00 101.87 ? 245 LEU E CB  1 
ATOM 6567 C CG  . LEU D 4 245 ? 99.975  138.727 59.362  1.00 101.50 ? 245 LEU E CG  1 
ATOM 6568 C CD1 . LEU D 4 245 ? 100.349 137.399 58.725  1.00 101.50 ? 245 LEU E CD1 1 
ATOM 6569 C CD2 . LEU D 4 245 ? 101.140 139.693 59.319  1.00 103.19 ? 245 LEU E CD2 1 
ATOM 6570 N N   . GLU D 4 246 ? 97.489  142.086 57.125  1.00 120.74 ? 246 GLU E N   1 
ATOM 6571 C CA  . GLU D 4 246 ? 96.426  142.601 56.278  1.00 120.98 ? 246 GLU E CA  1 
ATOM 6572 C C   . GLU D 4 246 ? 96.823  142.454 54.817  1.00 122.53 ? 246 GLU E C   1 
ATOM 6573 O O   . GLU D 4 246 ? 98.006  142.505 54.470  1.00 122.89 ? 246 GLU E O   1 
ATOM 6574 C CB  . GLU D 4 246 ? 96.114  144.069 56.597  1.00 120.04 ? 246 GLU E CB  1 
ATOM 6575 C CG  . GLU D 4 246 ? 97.318  144.992 56.523  1.00 121.52 ? 246 GLU E CG  1 
ATOM 6576 C CD  . GLU D 4 246 ? 96.985  146.414 56.930  1.00 121.54 ? 246 GLU E CD  1 
ATOM 6577 O OE1 . GLU D 4 246 ? 95.812  146.678 57.267  1.00 120.66 ? 246 GLU E OE1 1 
ATOM 6578 O OE2 . GLU D 4 246 ? 97.897  147.267 56.914  1.00 120.12 ? 246 GLU E OE2 1 
ATOM 6579 N N   . LEU D 4 247 ? 95.821  142.268 53.965  1.00 136.90 ? 247 LEU E N   1 
ATOM 6580 C CA  . LEU D 4 247 ? 96.054  142.109 52.534  1.00 137.58 ? 247 LEU E CA  1 
ATOM 6581 C C   . LEU D 4 247 ? 96.105  143.461 51.831  1.00 136.85 ? 247 LEU E C   1 
ATOM 6582 O O   . LEU D 4 247 ? 95.951  143.545 50.613  1.00 136.44 ? 247 LEU E O   1 
ATOM 6583 C CB  . LEU D 4 247 ? 94.970  141.229 51.911  1.00 137.36 ? 247 LEU E CB  1 
ATOM 6584 C CG  . LEU D 4 247 ? 94.890  139.797 52.442  1.00 137.87 ? 247 LEU E CG  1 
ATOM 6585 C CD1 . LEU D 4 247 ? 93.799  139.017 51.728  1.00 136.88 ? 247 LEU E CD1 1 
ATOM 6586 C CD2 . LEU D 4 247 ? 96.232  139.098 52.300  1.00 137.63 ? 247 LEU E CD2 1 
ATOM 6587 N N   . TYR E 5 160 ? 129.003 100.266 147.601 1.00 140.33 ? 107 TYR R N   1 
ATOM 6588 C CA  . TYR E 5 160 ? 128.309 99.389  146.666 1.00 141.90 ? 107 TYR R CA  1 
ATOM 6589 C C   . TYR E 5 160 ? 127.064 100.065 146.102 1.00 142.63 ? 107 TYR R C   1 
ATOM 6590 O O   . TYR E 5 160 ? 126.737 99.900  144.927 1.00 141.03 ? 107 TYR R O   1 
ATOM 6591 C CB  . TYR E 5 160 ? 127.931 98.071  147.346 1.00 140.43 ? 107 TYR R CB  1 
ATOM 6592 N N   . ILE E 5 161 ? 126.374 100.828 146.952 1.00 145.24 ? 108 ILE R N   1 
ATOM 6593 C CA  . ILE E 5 161 ? 125.168 101.524 146.516 1.00 144.42 ? 108 ILE R CA  1 
ATOM 6594 C C   . ILE E 5 161 ? 125.506 102.584 145.475 1.00 144.68 ? 108 ILE R C   1 
ATOM 6595 O O   . ILE E 5 161 ? 124.733 102.823 144.539 1.00 142.72 ? 108 ILE R O   1 
ATOM 6596 C CB  . ILE E 5 161 ? 124.436 102.133 147.727 1.00 142.02 ? 108 ILE R CB  1 
ATOM 6597 N N   . ASN E 5 162 ? 126.661 103.234 145.619 1.00 148.09 ? 109 ASN R N   1 
ATOM 6598 C CA  . ASN E 5 162 ? 127.074 104.269 144.679 1.00 147.44 ? 109 ASN R CA  1 
ATOM 6599 C C   . ASN E 5 162 ? 127.478 103.712 143.320 1.00 148.36 ? 109 ASN R C   1 
ATOM 6600 O O   . ASN E 5 162 ? 127.678 104.496 142.387 1.00 147.15 ? 109 ASN R O   1 
ATOM 6601 C CB  . ASN E 5 162 ? 128.232 105.078 145.267 1.00 145.29 ? 109 ASN R CB  1 
ATOM 6602 N N   . ILE E 5 163 ? 127.606 102.393 143.184 1.00 150.26 ? 110 ILE R N   1 
ATOM 6603 C CA  . ILE E 5 163 ? 128.000 101.785 141.918 1.00 149.19 ? 110 ILE R CA  1 
ATOM 6604 C C   . ILE E 5 163 ? 126.861 100.928 141.381 1.00 149.34 ? 110 ILE R C   1 
ATOM 6605 O O   . ILE E 5 163 ? 126.724 100.750 140.166 1.00 148.17 ? 110 ILE R O   1 
ATOM 6606 C CB  . ILE E 5 163 ? 129.286 100.955 142.075 1.00 147.34 ? 110 ILE R CB  1 
ATOM 6607 N N   . ILE E 5 164 ? 126.039 100.389 142.283 1.00 147.95 ? 111 ILE R N   1 
ATOM 6608 C CA  . ILE E 5 164 ? 124.925 99.544  141.861 1.00 146.75 ? 111 ILE R CA  1 
ATOM 6609 C C   . ILE E 5 164 ? 123.873 100.370 141.131 1.00 147.47 ? 111 ILE R C   1 
ATOM 6610 O O   . ILE E 5 164 ? 123.374 99.973  140.072 1.00 147.73 ? 111 ILE R O   1 
ATOM 6611 C CB  . ILE E 5 164 ? 124.323 98.804  143.069 1.00 145.10 ? 111 ILE R CB  1 
ATOM 6612 N N   . MET E 5 165 ? 123.516 101.526 141.690 1.00 147.71 ? 112 MET R N   1 
ATOM 6613 C CA  . MET E 5 165 ? 122.495 102.369 141.068 1.00 147.96 ? 112 MET R CA  1 
ATOM 6614 C C   . MET E 5 165 ? 122.888 102.856 139.678 1.00 147.81 ? 112 MET R C   1 
ATOM 6615 O O   . MET E 5 165 ? 122.048 102.775 138.765 1.00 146.50 ? 112 MET R O   1 
ATOM 6616 C CB  . MET E 5 165 ? 122.156 103.537 142.001 1.00 147.29 ? 112 MET R CB  1 
ATOM 6617 C CG  . MET E 5 165 ? 121.017 104.413 141.509 1.00 147.40 ? 112 MET R CG  1 
ATOM 6618 S SD  . MET E 5 165 ? 120.606 105.727 142.672 1.00 150.19 ? 112 MET R SD  1 
ATOM 6619 C CE  . MET E 5 165 ? 119.213 106.488 141.845 1.00 147.07 ? 112 MET R CE  1 
ATOM 6620 N N   . PRO E 5 166 ? 124.100 103.373 139.437 1.00 148.50 ? 113 PRO R N   1 
ATOM 6621 C CA  . PRO E 5 166 ? 124.459 103.739 138.055 1.00 147.53 ? 113 PRO R CA  1 
ATOM 6622 C C   . PRO E 5 166 ? 124.425 102.567 137.092 1.00 148.10 ? 113 PRO R C   1 
ATOM 6623 O O   . PRO E 5 166 ? 124.106 102.756 135.912 1.00 148.65 ? 113 PRO R O   1 
ATOM 6624 C CB  . PRO E 5 166 ? 125.877 104.307 138.198 1.00 147.10 ? 113 PRO R CB  1 
ATOM 6625 C CG  . PRO E 5 166 ? 125.962 104.757 139.606 1.00 147.64 ? 113 PRO R CG  1 
ATOM 6626 C CD  . PRO E 5 166 ? 125.157 103.768 140.387 1.00 148.07 ? 113 PRO R CD  1 
ATOM 6627 N N   . SER E 5 167 ? 124.754 101.360 137.558 1.00 148.51 ? 114 SER R N   1 
ATOM 6628 C CA  . SER E 5 167 ? 124.735 100.196 136.677 1.00 148.86 ? 114 SER R CA  1 
ATOM 6629 C C   . SER E 5 167 ? 123.317 99.860  136.229 1.00 148.25 ? 114 SER R C   1 
ATOM 6630 O O   . SER E 5 167 ? 123.100 99.485  135.071 1.00 145.92 ? 114 SER R O   1 
ATOM 6631 C CB  . SER E 5 167 ? 125.376 98.999  137.378 1.00 147.57 ? 114 SER R CB  1 
ATOM 6632 O OG  . SER E 5 167 ? 124.691 98.683  138.577 1.00 148.09 ? 114 SER R OG  1 
ATOM 6633 N N   . VAL E 5 168 ? 122.342 99.980  137.132 1.00 145.82 ? 115 VAL R N   1 
ATOM 6634 C CA  . VAL E 5 168 ? 120.960 99.664  136.783 1.00 145.06 ? 115 VAL R CA  1 
ATOM 6635 C C   . VAL E 5 168 ? 120.435 100.640 135.737 1.00 144.93 ? 115 VAL R C   1 
ATOM 6636 O O   . VAL E 5 168 ? 119.838 100.237 134.733 1.00 145.98 ? 115 VAL R O   1 
ATOM 6637 C CB  . VAL E 5 168 ? 120.076 99.659  138.043 1.00 145.77 ? 115 VAL R CB  1 
ATOM 6638 C CG1 . VAL E 5 168 ? 118.623 99.418  137.669 1.00 145.53 ? 115 VAL R CG1 1 
ATOM 6639 C CG2 . VAL E 5 168 ? 120.558 98.601  139.022 1.00 144.46 ? 115 VAL R CG2 1 
ATOM 6640 N N   . PHE E 5 169 ? 120.653 101.939 135.953 1.00 140.35 ? 116 PHE R N   1 
ATOM 6641 C CA  . PHE E 5 169 ? 120.191 102.931 134.988 1.00 139.48 ? 116 PHE R CA  1 
ATOM 6642 C C   . PHE E 5 169 ? 120.988 102.858 133.692 1.00 138.83 ? 116 PHE R C   1 
ATOM 6643 O O   . PHE E 5 169 ? 120.438 103.081 132.607 1.00 140.15 ? 116 PHE R O   1 
ATOM 6644 C CB  . PHE E 5 169 ? 120.271 104.331 135.592 1.00 140.57 ? 116 PHE R CB  1 
ATOM 6645 C CG  . PHE E 5 169 ? 119.205 104.613 136.611 1.00 141.21 ? 116 PHE R CG  1 
ATOM 6646 C CD1 . PHE E 5 169 ? 117.972 105.105 136.222 1.00 140.24 ? 116 PHE R CD1 1 
ATOM 6647 C CD2 . PHE E 5 169 ? 119.434 104.383 137.956 1.00 140.82 ? 116 PHE R CD2 1 
ATOM 6648 C CE1 . PHE E 5 169 ? 116.989 105.365 137.155 1.00 140.43 ? 116 PHE R CE1 1 
ATOM 6649 C CE2 . PHE E 5 169 ? 118.454 104.640 138.894 1.00 139.84 ? 116 PHE R CE2 1 
ATOM 6650 C CZ  . PHE E 5 169 ? 117.231 105.132 138.493 1.00 140.70 ? 116 PHE R CZ  1 
ATOM 6651 N N   . GLY E 5 170 ? 122.284 102.559 133.783 1.00 137.79 ? 117 GLY R N   1 
ATOM 6652 C CA  . GLY E 5 170 ? 123.091 102.451 132.580 1.00 138.45 ? 117 GLY R CA  1 
ATOM 6653 C C   . GLY E 5 170 ? 122.666 101.301 131.688 1.00 139.11 ? 117 GLY R C   1 
ATOM 6654 O O   . GLY E 5 170 ? 122.621 101.438 130.462 1.00 138.57 ? 117 GLY R O   1 
ATOM 6655 N N   . THR E 5 171 ? 122.354 100.149 132.287 1.00 136.89 ? 118 THR R N   1 
ATOM 6656 C CA  . THR E 5 171 ? 121.902 99.006  131.500 1.00 137.26 ? 118 THR R CA  1 
ATOM 6657 C C   . THR E 5 171 ? 120.568 99.292  130.821 1.00 136.27 ? 118 THR R C   1 
ATOM 6658 O O   . THR E 5 171 ? 120.378 98.963  129.644 1.00 135.01 ? 118 THR R O   1 
ATOM 6659 C CB  . THR E 5 171 ? 121.791 97.769  132.392 1.00 138.30 ? 118 THR R CB  1 
ATOM 6660 O OG1 . THR E 5 171 ? 123.055 97.512  133.016 1.00 138.49 ? 118 THR R OG1 1 
ATOM 6661 C CG2 . THR E 5 171 ? 121.381 96.554  131.574 1.00 136.31 ? 118 THR R CG2 1 
ATOM 6662 N N   . ILE E 5 172 ? 119.634 99.909  131.547 1.00 131.91 ? 119 ILE R N   1 
ATOM 6663 C CA  . ILE E 5 172 ? 118.325 100.217 130.979 1.00 129.57 ? 119 ILE R CA  1 
ATOM 6664 C C   . ILE E 5 172 ? 118.451 101.232 129.849 1.00 129.39 ? 119 ILE R C   1 
ATOM 6665 O O   . ILE E 5 172 ? 117.811 101.093 128.799 1.00 130.42 ? 119 ILE R O   1 
ATOM 6666 C CB  . ILE E 5 172 ? 117.373 100.712 132.082 1.00 130.00 ? 119 ILE R CB  1 
ATOM 6667 C CG1 . ILE E 5 172 ? 117.123 99.602  133.104 1.00 129.66 ? 119 ILE R CG1 1 
ATOM 6668 C CG2 . ILE E 5 172 ? 116.061 101.193 131.483 1.00 129.91 ? 119 ILE R CG2 1 
ATOM 6669 C CD1 . ILE E 5 172 ? 116.217 100.014 134.240 1.00 129.34 ? 119 ILE R CD1 1 
ATOM 6670 N N   . CYS E 5 173 ? 119.271 102.266 130.043 1.00 127.02 ? 120 CYS R N   1 
ATOM 6671 C CA  . CYS E 5 173 ? 119.396 103.315 129.036 1.00 126.66 ? 120 CYS R CA  1 
ATOM 6672 C C   . CYS E 5 173 ? 119.959 102.770 127.729 1.00 126.53 ? 120 CYS R C   1 
ATOM 6673 O O   . CYS E 5 173 ? 119.447 103.073 126.646 1.00 125.49 ? 120 CYS R O   1 
ATOM 6674 C CB  . CYS E 5 173 ? 120.274 104.448 129.567 1.00 125.72 ? 120 CYS R CB  1 
ATOM 6675 S SG  . CYS E 5 173 ? 120.492 105.823 128.417 1.00 128.67 ? 120 CYS R SG  1 
ATOM 6676 N N   . LEU E 5 174 ? 121.013 101.958 127.809 1.00 126.47 ? 121 LEU R N   1 
ATOM 6677 C CA  . LEU E 5 174 ? 121.630 101.438 126.593 1.00 126.31 ? 121 LEU R CA  1 
ATOM 6678 C C   . LEU E 5 174 ? 120.728 100.419 125.908 1.00 125.87 ? 121 LEU R C   1 
ATOM 6679 O O   . LEU E 5 174 ? 120.547 100.459 124.685 1.00 125.95 ? 121 LEU R O   1 
ATOM 6680 C CB  . LEU E 5 174 ? 122.993 100.826 126.915 1.00 125.86 ? 121 LEU R CB  1 
ATOM 6681 C CG  . LEU E 5 174 ? 124.069 101.806 127.386 1.00 125.57 ? 121 LEU R CG  1 
ATOM 6682 C CD1 . LEU E 5 174 ? 125.379 101.081 127.646 1.00 124.96 ? 121 LEU R CD1 1 
ATOM 6683 C CD2 . LEU E 5 174 ? 124.260 102.917 126.366 1.00 124.26 ? 121 LEU R CD2 1 
ATOM 6684 N N   . LEU E 5 175 ? 120.155 99.495  126.680 1.00 122.78 ? 122 LEU R N   1 
ATOM 6685 C CA  . LEU E 5 175 ? 119.276 98.487  126.096 1.00 122.32 ? 122 LEU R CA  1 
ATOM 6686 C C   . LEU E 5 175 ? 118.013 99.117  125.521 1.00 121.64 ? 122 LEU R C   1 
ATOM 6687 O O   . LEU E 5 175 ? 117.557 98.729  124.440 1.00 121.21 ? 122 LEU R O   1 
ATOM 6688 C CB  . LEU E 5 175 ? 118.923 97.432  127.144 1.00 121.40 ? 122 LEU R CB  1 
ATOM 6689 C CG  . LEU E 5 175 ? 118.193 96.190  126.634 1.00 121.29 ? 122 LEU R CG  1 
ATOM 6690 C CD1 . LEU E 5 175 ? 119.058 95.452  125.625 1.00 120.48 ? 122 LEU R CD1 1 
ATOM 6691 C CD2 . LEU E 5 175 ? 117.813 95.278  127.790 1.00 120.22 ? 122 LEU R CD2 1 
ATOM 6692 N N   . GLY E 5 176 ? 117.437 100.088 126.230 1.00 120.59 ? 123 GLY R N   1 
ATOM 6693 C CA  . GLY E 5 176 ? 116.223 100.726 125.748 1.00 119.25 ? 123 GLY R CA  1 
ATOM 6694 C C   . GLY E 5 176 ? 116.436 101.539 124.485 1.00 119.74 ? 123 GLY R C   1 
ATOM 6695 O O   . GLY E 5 176 ? 115.572 101.571 123.605 1.00 121.27 ? 123 GLY R O   1 
ATOM 6696 N N   . ILE E 5 177 ? 117.581 102.216 124.381 1.00 116.27 ? 124 ILE R N   1 
ATOM 6697 C CA  . ILE E 5 177 ? 117.867 103.006 123.186 1.00 117.27 ? 124 ILE R CA  1 
ATOM 6698 C C   . ILE E 5 177 ? 117.990 102.101 121.968 1.00 117.32 ? 124 ILE R C   1 
ATOM 6699 O O   . ILE E 5 177 ? 117.444 102.398 120.899 1.00 118.29 ? 124 ILE R O   1 
ATOM 6700 C CB  . ILE E 5 177 ? 119.135 103.855 123.395 1.00 116.94 ? 124 ILE R CB  1 
ATOM 6701 C CG1 . ILE E 5 177 ? 118.834 105.048 124.301 1.00 117.71 ? 124 ILE R CG1 1 
ATOM 6702 C CG2 . ILE E 5 177 ? 119.690 104.330 122.063 1.00 116.52 ? 124 ILE R CG2 1 
ATOM 6703 C CD1 . ILE E 5 177 ? 120.035 105.925 124.566 1.00 116.18 ? 124 ILE R CD1 1 
ATOM 6704 N N   . ILE E 5 178 ? 118.704 100.983 122.110 1.00 117.45 ? 125 ILE R N   1 
ATOM 6705 C CA  . ILE E 5 178 ? 118.865 100.056 120.993 1.00 119.13 ? 125 ILE R CA  1 
ATOM 6706 C C   . ILE E 5 178 ? 117.522 99.458  120.593 1.00 118.91 ? 125 ILE R C   1 
ATOM 6707 O O   . ILE E 5 178 ? 117.202 99.354  119.403 1.00 117.53 ? 125 ILE R O   1 
ATOM 6708 C CB  . ILE E 5 178 ? 119.886 98.961  121.351 1.00 119.00 ? 125 ILE R CB  1 
ATOM 6709 C CG1 . ILE E 5 178 ? 121.252 99.582  121.646 1.00 118.87 ? 125 ILE R CG1 1 
ATOM 6710 C CG2 . ILE E 5 178 ? 119.997 97.945  120.226 1.00 116.81 ? 125 ILE R CG2 1 
ATOM 6711 C CD1 . ILE E 5 178 ? 122.309 98.572  122.033 1.00 117.97 ? 125 ILE R CD1 1 
ATOM 6712 N N   . GLY E 5 179 ? 116.715 99.059  121.578 1.00 113.16 ? 126 GLY R N   1 
ATOM 6713 C CA  . GLY E 5 179 ? 115.424 98.466  121.266 1.00 108.23 ? 126 GLY R CA  1 
ATOM 6714 C C   . GLY E 5 179 ? 114.490 99.429  120.559 1.00 110.22 ? 126 GLY R C   1 
ATOM 6715 O O   . GLY E 5 179 ? 113.864 99.081  119.556 1.00 113.32 ? 126 GLY R O   1 
ATOM 6716 N N   . ASN E 5 180 ? 114.389 100.659 121.069 1.00 106.08 ? 127 ASN R N   1 
ATOM 6717 C CA  . ASN E 5 180 ? 113.525 101.646 120.430 1.00 103.70 ? 127 ASN R CA  1 
ATOM 6718 C C   . ASN E 5 180 ? 114.061 102.063 119.069 1.00 103.95 ? 127 ASN R C   1 
ATOM 6719 O O   . ASN E 5 180 ? 113.277 102.336 118.154 1.00 105.18 ? 127 ASN R O   1 
ATOM 6720 C CB  . ASN E 5 180 ? 113.353 102.868 121.330 1.00 104.42 ? 127 ASN R CB  1 
ATOM 6721 C CG  . ASN E 5 180 ? 112.386 102.621 122.470 1.00 105.07 ? 127 ASN R CG  1 
ATOM 6722 O OD1 . ASN E 5 180 ? 111.172 102.720 122.299 1.00 101.86 ? 127 ASN R OD1 1 
ATOM 6723 N ND2 . ASN E 5 180 ? 112.919 102.300 123.642 1.00 106.41 ? 127 ASN R ND2 1 
ATOM 6724 N N   . SER E 5 181 ? 115.385 102.128 118.917 1.00 107.75 ? 128 SER R N   1 
ATOM 6725 C CA  . SER E 5 181 ? 115.962 102.465 117.620 1.00 106.88 ? 128 SER R CA  1 
ATOM 6726 C C   . SER E 5 181 ? 115.723 101.353 116.607 1.00 109.07 ? 128 SER R C   1 
ATOM 6727 O O   . SER E 5 181 ? 115.530 101.622 115.416 1.00 108.52 ? 128 SER R O   1 
ATOM 6728 C CB  . SER E 5 181 ? 117.455 102.746 117.766 1.00 107.23 ? 128 SER R CB  1 
ATOM 6729 O OG  . SER E 5 181 ? 117.686 103.790 118.696 1.00 108.87 ? 128 SER R OG  1 
ATOM 6730 N N   . THR E 5 182 ? 115.743 100.096 117.059 1.00 112.63 ? 129 THR R N   1 
ATOM 6731 C CA  . THR E 5 182 ? 115.475 98.978  116.160 1.00 112.02 ? 129 THR R CA  1 
ATOM 6732 C C   . THR E 5 182 ? 114.058 99.040  115.604 1.00 109.30 ? 129 THR R C   1 
ATOM 6733 O O   . THR E 5 182 ? 113.840 98.804  114.410 1.00 108.97 ? 129 THR R O   1 
ATOM 6734 C CB  . THR E 5 182 ? 115.705 97.654  116.887 1.00 110.49 ? 129 THR R CB  1 
ATOM 6735 O OG1 . THR E 5 182 ? 117.043 97.614  117.397 1.00 113.99 ? 129 THR R OG1 1 
ATOM 6736 C CG2 . THR E 5 182 ? 115.496 96.482  115.944 1.00 107.54 ? 129 THR R CG2 1 
ATOM 6737 N N   . VAL E 5 183 ? 113.080 99.358  116.455 1.00 102.29 ? 130 VAL R N   1 
ATOM 6738 C CA  . VAL E 5 183 ? 111.698 99.465  115.995 1.00 99.86  ? 130 VAL R CA  1 
ATOM 6739 C C   . VAL E 5 183 ? 111.554 100.614 115.007 1.00 101.37 ? 130 VAL R C   1 
ATOM 6740 O O   . VAL E 5 183 ? 110.882 100.485 113.977 1.00 104.86 ? 130 VAL R O   1 
ATOM 6741 C CB  . VAL E 5 183 ? 110.745 99.623  117.193 1.00 98.94  ? 130 VAL R CB  1 
ATOM 6742 C CG1 . VAL E 5 183 ? 109.312 99.758  116.712 1.00 97.63  ? 130 VAL R CG1 1 
ATOM 6743 C CG2 . VAL E 5 183 ? 110.883 98.440  118.134 1.00 101.28 ? 130 VAL R CG2 1 
ATOM 6744 N N   . ILE E 5 184 ? 112.175 101.756 115.305 1.00 100.14 ? 131 ILE R N   1 
ATOM 6745 C CA  . ILE E 5 184 ? 112.110 102.894 114.393 1.00 100.68 ? 131 ILE R CA  1 
ATOM 6746 C C   . ILE E 5 184 ? 112.803 102.562 113.078 1.00 103.63 ? 131 ILE R C   1 
ATOM 6747 O O   . ILE E 5 184 ? 112.292 102.869 111.995 1.00 101.96 ? 131 ILE R O   1 
ATOM 6748 C CB  . ILE E 5 184 ? 112.716 104.145 115.054 1.00 100.74 ? 131 ILE R CB  1 
ATOM 6749 C CG1 . ILE E 5 184 ? 111.889 104.553 116.274 1.00 101.42 ? 131 ILE R CG1 1 
ATOM 6750 C CG2 . ILE E 5 184 ? 112.789 105.289 114.060 1.00 102.28 ? 131 ILE R CG2 1 
ATOM 6751 C CD1 . ILE E 5 184 ? 112.404 105.787 116.977 1.00 100.85 ? 131 ILE R CD1 1 
ATOM 6752 N N   . PHE E 5 185 ? 113.974 101.926 113.151 1.00 110.63 ? 132 PHE R N   1 
ATOM 6753 C CA  . PHE E 5 185 ? 114.706 101.579 111.937 1.00 110.45 ? 132 PHE R CA  1 
ATOM 6754 C C   . PHE E 5 185 ? 113.934 100.580 111.084 1.00 111.37 ? 132 PHE R C   1 
ATOM 6755 O O   . PHE E 5 185 ? 113.881 100.714 109.856 1.00 111.97 ? 132 PHE R O   1 
ATOM 6756 C CB  . PHE E 5 185 ? 116.084 101.023 112.295 1.00 110.10 ? 132 PHE R CB  1 
ATOM 6757 C CG  . PHE E 5 185 ? 116.798 100.384 111.139 1.00 112.19 ? 132 PHE R CG  1 
ATOM 6758 C CD1 . PHE E 5 185 ? 117.407 101.161 110.169 1.00 110.69 ? 132 PHE R CD1 1 
ATOM 6759 C CD2 . PHE E 5 185 ? 116.869 99.005  111.028 1.00 110.44 ? 132 PHE R CD2 1 
ATOM 6760 C CE1 . PHE E 5 185 ? 118.066 100.575 109.105 1.00 111.86 ? 132 PHE R CE1 1 
ATOM 6761 C CE2 . PHE E 5 185 ? 117.527 98.414  109.968 1.00 109.15 ? 132 PHE R CE2 1 
ATOM 6762 C CZ  . PHE E 5 185 ? 118.126 99.200  109.005 1.00 111.46 ? 132 PHE R CZ  1 
ATOM 6763 N N   . ALA E 5 186 ? 113.334 99.568  111.715 1.00 110.22 ? 133 ALA R N   1 
ATOM 6764 C CA  . ALA E 5 186 ? 112.622 98.546  110.954 1.00 107.26 ? 133 ALA R CA  1 
ATOM 6765 C C   . ALA E 5 186 ? 111.388 99.116  110.266 1.00 105.93 ? 133 ALA R C   1 
ATOM 6766 O O   . ALA E 5 186 ? 111.126 98.806  109.099 1.00 107.47 ? 133 ALA R O   1 
ATOM 6767 C CB  . ALA E 5 186 ? 112.238 97.384  111.868 1.00 105.77 ? 133 ALA R CB  1 
ATOM 6768 N N   . VAL E 5 187 ? 110.617 99.949  110.969 1.00 102.57 ? 134 VAL R N   1 
ATOM 6769 C CA  . VAL E 5 187 ? 109.405 100.508 110.377 1.00 104.83 ? 134 VAL R CA  1 
ATOM 6770 C C   . VAL E 5 187 ? 109.755 101.485 109.262 1.00 107.00 ? 134 VAL R C   1 
ATOM 6771 O O   . VAL E 5 187 ? 109.094 101.517 108.217 1.00 107.47 ? 134 VAL R O   1 
ATOM 6772 C CB  . VAL E 5 187 ? 108.533 101.164 111.462 1.00 105.44 ? 134 VAL R CB  1 
ATOM 6773 C CG1 . VAL E 5 187 ? 107.345 101.872 110.834 1.00 102.58 ? 134 VAL R CG1 1 
ATOM 6774 C CG2 . VAL E 5 187 ? 108.058 100.120 112.455 1.00 104.46 ? 134 VAL R CG2 1 
ATOM 6775 N N   . VAL E 5 188 ? 110.793 102.300 109.464 1.00 106.83 ? 135 VAL R N   1 
ATOM 6776 C CA  . VAL E 5 188 ? 111.224 103.220 108.415 1.00 107.61 ? 135 VAL R CA  1 
ATOM 6777 C C   . VAL E 5 188 ? 111.702 102.445 107.193 1.00 107.42 ? 135 VAL R C   1 
ATOM 6778 O O   . VAL E 5 188 ? 111.363 102.784 106.052 1.00 107.51 ? 135 VAL R O   1 
ATOM 6779 C CB  . VAL E 5 188 ? 112.308 104.173 108.950 1.00 106.77 ? 135 VAL R CB  1 
ATOM 6780 C CG1 . VAL E 5 188 ? 113.016 104.874 107.804 1.00 105.83 ? 135 VAL R CG1 1 
ATOM 6781 C CG2 . VAL E 5 188 ? 111.688 105.194 109.889 1.00 106.69 ? 135 VAL R CG2 1 
ATOM 6782 N N   . LYS E 5 189 ? 112.490 101.390 107.411 1.00 109.93 ? 136 LYS R N   1 
ATOM 6783 C CA  . LYS E 5 189 ? 112.894 100.532 106.302 1.00 109.24 ? 136 LYS R CA  1 
ATOM 6784 C C   . LYS E 5 189 ? 111.686 99.848  105.675 1.00 112.21 ? 136 LYS R C   1 
ATOM 6785 O O   . LYS E 5 189 ? 111.617 99.691  104.451 1.00 113.09 ? 136 LYS R O   1 
ATOM 6786 C CB  . LYS E 5 189 ? 113.912 99.496  106.780 1.00 107.89 ? 136 LYS R CB  1 
ATOM 6787 N N   . LYS E 5 190 ? 110.727 99.429  106.504 1.00 108.80 ? 137 LYS R N   1 
ATOM 6788 C CA  . LYS E 5 190 ? 109.500 98.831  105.990 1.00 105.90 ? 137 LYS R CA  1 
ATOM 6789 C C   . LYS E 5 190 ? 108.695 99.826  105.165 1.00 106.63 ? 137 LYS R C   1 
ATOM 6790 O O   . LYS E 5 190 ? 108.012 99.433  104.212 1.00 106.92 ? 137 LYS R O   1 
ATOM 6791 C CB  . LYS E 5 190 ? 108.658 98.294  107.148 1.00 105.98 ? 137 LYS R CB  1 
ATOM 6792 C CG  . LYS E 5 190 ? 107.368 97.610  106.736 1.00 104.27 ? 137 LYS R CG  1 
ATOM 6793 C CD  . LYS E 5 190 ? 106.586 97.153  107.955 1.00 105.62 ? 137 LYS R CD  1 
ATOM 6794 C CE  . LYS E 5 190 ? 105.280 96.487  107.559 1.00 107.18 ? 137 LYS R CE  1 
ATOM 6795 N NZ  . LYS E 5 190 ? 104.500 96.050  108.749 1.00 104.95 ? 137 LYS R NZ  1 
ATOM 6796 N N   . SER E 5 191 ? 108.756 101.109 105.511 1.00 104.61 ? 138 SER R N   1 
ATOM 6797 C CA  . SER E 5 191 ? 108.042 102.143 104.776 1.00 106.93 ? 138 SER R CA  1 
ATOM 6798 C C   . SER E 5 191 ? 108.828 102.670 103.583 1.00 105.44 ? 138 SER R C   1 
ATOM 6799 O O   . SER E 5 191 ? 108.307 103.509 102.841 1.00 103.80 ? 138 SER R O   1 
ATOM 6800 C CB  . SER E 5 191 ? 107.683 103.302 105.710 1.00 107.11 ? 138 SER R CB  1 
ATOM 6801 O OG  . SER E 5 191 ? 108.848 103.909 106.240 1.00 107.03 ? 138 SER R OG  1 
ATOM 6802 N N   . LYS E 5 192 ? 110.061 102.197 103.385 1.00 97.46  ? 139 LYS R N   1 
ATOM 6803 C CA  . LYS E 5 192 ? 110.900 102.590 102.251 1.00 98.90  ? 139 LYS R CA  1 
ATOM 6804 C C   . LYS E 5 192 ? 111.108 104.104 102.197 1.00 100.54 ? 139 LYS R C   1 
ATOM 6805 O O   . LYS E 5 192 ? 110.995 104.731 101.141 1.00 99.47  ? 139 LYS R O   1 
ATOM 6806 C CB  . LYS E 5 192 ? 110.325 102.064 100.933 1.00 96.16  ? 139 LYS R CB  1 
ATOM 6807 C CG  . LYS E 5 192 ? 110.755 100.644 100.579 1.00 96.87  ? 139 LYS R CG  1 
ATOM 6808 C CD  . LYS E 5 192 ? 110.144 99.590  101.496 1.00 98.09  ? 139 LYS R CD  1 
ATOM 6809 C CE  . LYS E 5 192 ? 108.712 99.241  101.106 1.00 97.10  ? 139 LYS R CE  1 
ATOM 6810 N NZ  . LYS E 5 192 ? 107.721 100.275 101.514 1.00 97.36  ? 139 LYS R NZ  1 
ATOM 6811 N N   . LEU E 5 193 ? 111.416 104.689 103.355 1.00 102.37 ? 140 LEU R N   1 
ATOM 6812 C CA  . LEU E 5 193 ? 111.707 106.118 103.481 1.00 103.56 ? 140 LEU R CA  1 
ATOM 6813 C C   . LEU E 5 193 ? 110.540 106.969 102.974 1.00 105.85 ? 140 LEU R C   1 
ATOM 6814 O O   . LEU E 5 193 ? 110.681 107.806 102.080 1.00 103.90 ? 140 LEU R O   1 
ATOM 6815 C CB  . LEU E 5 193 ? 113.009 106.478 102.756 1.00 106.75 ? 140 LEU R CB  1 
ATOM 6816 C CG  . LEU E 5 193 ? 114.292 105.848 103.300 1.00 106.73 ? 140 LEU R CG  1 
ATOM 6817 C CD1 . LEU E 5 193 ? 115.476 106.201 102.415 1.00 105.05 ? 140 LEU R CD1 1 
ATOM 6818 C CD2 . LEU E 5 193 ? 114.540 106.295 104.731 1.00 103.75 ? 140 LEU R CD2 1 
ATOM 6819 N N   . HIS E 5 194 ? 109.374 106.737 103.568 1.00 115.08 ? 141 HIS R N   1 
ATOM 6820 C CA  . HIS E 5 194 ? 108.170 107.476 103.215 1.00 114.62 ? 141 HIS R CA  1 
ATOM 6821 C C   . HIS E 5 194 ? 107.195 107.377 104.378 1.00 114.93 ? 141 HIS R C   1 
ATOM 6822 O O   . HIS E 5 194 ? 107.377 106.577 105.299 1.00 116.12 ? 141 HIS R O   1 
ATOM 6823 C CB  . HIS E 5 194 ? 107.546 106.947 101.919 1.00 113.37 ? 141 HIS R CB  1 
ATOM 6824 C CG  . HIS E 5 194 ? 106.588 107.900 101.277 1.00 115.79 ? 141 HIS R CG  1 
ATOM 6825 N ND1 . HIS E 5 194 ? 106.997 109.054 100.645 1.00 116.80 ? 141 HIS R ND1 1 
ATOM 6826 C CD2 . HIS E 5 194 ? 105.238 107.872 101.172 1.00 114.63 ? 141 HIS R CD2 1 
ATOM 6827 C CE1 . HIS E 5 194 ? 105.942 109.695 100.176 1.00 115.18 ? 141 HIS R CE1 1 
ATOM 6828 N NE2 . HIS E 5 194 ? 104.862 108.999 100.482 1.00 114.70 ? 141 HIS R NE2 1 
ATOM 6829 N N   . TRP E 5 195 ? 106.161 108.215 104.333 1.00 116.61 ? 142 TRP R N   1 
ATOM 6830 C CA  . TRP E 5 195 ? 105.145 108.197 105.376 1.00 116.98 ? 142 TRP R CA  1 
ATOM 6831 C C   . TRP E 5 195 ? 104.448 106.844 105.417 1.00 116.75 ? 142 TRP R C   1 
ATOM 6832 O O   . TRP E 5 195 ? 104.090 106.278 104.381 1.00 116.76 ? 142 TRP R O   1 
ATOM 6833 C CB  . TRP E 5 195 ? 104.125 109.313 105.149 1.00 118.02 ? 142 TRP R CB  1 
ATOM 6834 C CG  . TRP E 5 195 ? 104.719 110.690 105.189 1.00 119.22 ? 142 TRP R CG  1 
ATOM 6835 C CD1 . TRP E 5 195 ? 104.898 111.538 104.135 1.00 116.52 ? 142 TRP R CD1 1 
ATOM 6836 C CD2 . TRP E 5 195 ? 105.222 111.374 106.343 1.00 119.26 ? 142 TRP R CD2 1 
ATOM 6837 N NE1 . TRP E 5 195 ? 105.474 112.709 104.562 1.00 116.69 ? 142 TRP R NE1 1 
ATOM 6838 C CE2 . TRP E 5 195 ? 105.684 112.633 105.913 1.00 118.45 ? 142 TRP R CE2 1 
ATOM 6839 C CE3 . TRP E 5 195 ? 105.323 111.045 107.698 1.00 117.67 ? 142 TRP R CE3 1 
ATOM 6840 C CZ2 . TRP E 5 195 ? 106.239 113.562 106.789 1.00 116.23 ? 142 TRP R CZ2 1 
ATOM 6841 C CZ3 . TRP E 5 195 ? 105.876 111.969 108.565 1.00 118.04 ? 142 TRP R CZ3 1 
ATOM 6842 C CH2 . TRP E 5 195 ? 106.326 113.212 108.108 1.00 116.59 ? 142 TRP R CH2 1 
ATOM 6843 N N   . CYS E 5 196 ? 104.261 106.324 106.628 1.00 111.71 ? 143 CYS R N   1 
ATOM 6844 C CA  . CYS E 5 196 ? 103.700 104.992 106.796 1.00 110.00 ? 143 CYS R CA  1 
ATOM 6845 C C   . CYS E 5 196 ? 102.247 104.950 106.341 1.00 108.30 ? 143 CYS R C   1 
ATOM 6846 O O   . CYS E 5 196 ? 101.451 105.840 106.653 1.00 107.81 ? 143 CYS R O   1 
ATOM 6847 C CB  . CYS E 5 196 ? 103.805 104.556 108.256 1.00 110.87 ? 143 CYS R CB  1 
ATOM 6848 S SG  . CYS E 5 196 ? 105.493 104.522 108.902 1.00 114.36 ? 143 CYS R SG  1 
ATOM 6849 N N   . ASN E 5 197 ? 101.905 103.900 105.598 1.00 100.42 ? 144 ASN R N   1 
ATOM 6850 C CA  . ASN E 5 197 ? 100.553 103.688 105.101 1.00 102.63 ? 144 ASN R CA  1 
ATOM 6851 C C   . ASN E 5 197 ? 99.742  102.749 105.980 1.00 101.08 ? 144 ASN R C   1 
ATOM 6852 O O   . ASN E 5 197 ? 98.588  102.456 105.652 1.00 103.48 ? 144 ASN R O   1 
ATOM 6853 C CB  . ASN E 5 197 ? 100.598 103.139 103.671 1.00 102.22 ? 144 ASN R CB  1 
ATOM 6854 C CG  . ASN E 5 197 ? 101.380 104.031 102.727 1.00 103.77 ? 144 ASN R CG  1 
ATOM 6855 O OD1 . ASN E 5 197 ? 101.415 105.250 102.892 1.00 104.08 ? 144 ASN R OD1 1 
ATOM 6856 N ND2 . ASN E 5 197 ? 102.014 103.425 101.730 1.00 102.20 ? 144 ASN R ND2 1 
ATOM 6857 N N   . ASN E 5 198 ? 100.310 102.272 107.082 1.00 82.96  ? 145 ASN R N   1 
ATOM 6858 C CA  . ASN E 5 198 ? 99.656  101.313 107.959 1.00 80.42  ? 145 ASN R CA  1 
ATOM 6859 C C   . ASN E 5 198 ? 99.391  101.954 109.313 1.00 83.08  ? 145 ASN R C   1 
ATOM 6860 O O   . ASN E 5 198 ? 100.304 102.515 109.926 1.00 86.40  ? 145 ASN R O   1 
ATOM 6861 C CB  . ASN E 5 198 ? 100.520 100.061 108.127 1.00 82.14  ? 145 ASN R CB  1 
ATOM 6862 C CG  . ASN E 5 198 ? 99.744  98.888  108.689 1.00 87.28  ? 145 ASN R CG  1 
ATOM 6863 O OD1 . ASN E 5 198 ? 98.537  98.770  108.482 1.00 87.90  ? 145 ASN R OD1 1 
ATOM 6864 N ND2 . ASN E 5 198 ? 100.436 98.012  109.406 1.00 86.43  ? 145 ASN R ND2 1 
ATOM 6865 N N   . VAL E 5 199 ? 98.139  101.874 109.770 1.00 69.26  ? 146 VAL R N   1 
ATOM 6866 C CA  . VAL E 5 199 ? 97.779  102.475 111.056 1.00 69.20  ? 146 VAL R CA  1 
ATOM 6867 C C   . VAL E 5 199 ? 98.567  101.870 112.213 1.00 70.37  ? 146 VAL R C   1 
ATOM 6868 O O   . VAL E 5 199 ? 99.098  102.635 113.034 1.00 71.73  ? 146 VAL R O   1 
ATOM 6869 C CB  . VAL E 5 199 ? 96.257  102.398 111.269 1.00 69.61  ? 146 VAL R CB  1 
ATOM 6870 C CG1 . VAL E 5 199 ? 95.877  102.996 112.612 1.00 67.92  ? 146 VAL R CG1 1 
ATOM 6871 C CG2 . VAL E 5 199 ? 95.531  103.106 110.146 1.00 71.56  ? 146 VAL R CG2 1 
ATOM 6872 N N   . PRO E 5 200 ? 98.684  100.543 112.351 1.00 71.23  ? 147 PRO R N   1 
ATOM 6873 C CA  . PRO E 5 200 ? 99.514  100.008 113.443 1.00 68.72  ? 147 PRO R CA  1 
ATOM 6874 C C   . PRO E 5 200 ? 100.962 100.454 113.380 1.00 75.44  ? 147 PRO R C   1 
ATOM 6875 O O   . PRO E 5 200 ? 101.601 100.598 114.429 1.00 77.21  ? 147 PRO R O   1 
ATOM 6876 C CB  . PRO E 5 200 ? 99.389  98.491  113.263 1.00 71.88  ? 147 PRO R CB  1 
ATOM 6877 C CG  . PRO E 5 200 ? 98.103  98.307  112.572 1.00 77.71  ? 147 PRO R CG  1 
ATOM 6878 C CD  . PRO E 5 200 ? 97.997  99.458  111.629 1.00 74.52  ? 147 PRO R CD  1 
ATOM 6879 N N   . ASP E 5 201 ? 101.507 100.661 112.180 1.00 81.49  ? 148 ASP R N   1 
ATOM 6880 C CA  . ASP E 5 201 ? 102.889 101.113 112.072 1.00 79.33  ? 148 ASP R CA  1 
ATOM 6881 C C   . ASP E 5 201 ? 103.033 102.575 112.467 1.00 79.96  ? 148 ASP R C   1 
ATOM 6882 O O   . ASP E 5 201 ? 104.119 103.000 112.873 1.00 81.82  ? 148 ASP R O   1 
ATOM 6883 C CB  . ASP E 5 201 ? 103.402 100.888 110.652 1.00 83.07  ? 148 ASP R CB  1 
ATOM 6884 C CG  . ASP E 5 201 ? 103.551 99.418  110.315 1.00 87.47  ? 148 ASP R CG  1 
ATOM 6885 O OD1 . ASP E 5 201 ? 102.532 98.698  110.336 1.00 85.25  ? 148 ASP R OD1 1 
ATOM 6886 O OD2 . ASP E 5 201 ? 104.685 98.983  110.027 1.00 89.62  ? 148 ASP R OD2 1 
ATOM 6887 N N   . ILE E 5 202 ? 101.961 103.359 112.348 1.00 74.88  ? 149 ILE R N   1 
ATOM 6888 C CA  . ILE E 5 202 ? 102.010 104.755 112.773 1.00 72.92  ? 149 ILE R CA  1 
ATOM 6889 C C   . ILE E 5 202 ? 102.127 104.842 114.289 1.00 76.97  ? 149 ILE R C   1 
ATOM 6890 O O   . ILE E 5 202 ? 102.946 105.598 114.823 1.00 74.77  ? 149 ILE R O   1 
ATOM 6891 C CB  . ILE E 5 202 ? 100.777 105.517 112.257 1.00 69.88  ? 149 ILE R CB  1 
ATOM 6892 C CG1 . ILE E 5 202 ? 100.787 105.581 110.731 1.00 74.44  ? 149 ILE R CG1 1 
ATOM 6893 C CG2 . ILE E 5 202 ? 100.730 106.912 112.840 1.00 72.30  ? 149 ILE R CG2 1 
ATOM 6894 C CD1 . ILE E 5 202 ? 99.589  106.290 110.149 1.00 74.79  ? 149 ILE R CD1 1 
ATOM 6895 N N   . PHE E 5 203 ? 101.311 104.066 115.005 1.00 65.97  ? 150 PHE R N   1 
ATOM 6896 C CA  . PHE E 5 203 ? 101.375 104.068 116.462 1.00 54.37  ? 150 PHE R CA  1 
ATOM 6897 C C   . PHE E 5 203 ? 102.699 103.512 116.968 1.00 58.64  ? 150 PHE R C   1 
ATOM 6898 O O   . PHE E 5 203 ? 103.281 104.052 117.915 1.00 72.14  ? 150 PHE R O   1 
ATOM 6899 C CB  . PHE E 5 203 ? 100.214 103.264 117.042 1.00 56.42  ? 150 PHE R CB  1 
ATOM 6900 C CG  . PHE E 5 203 ? 98.885  103.945 116.933 1.00 59.85  ? 150 PHE R CG  1 
ATOM 6901 C CD1 . PHE E 5 203 ? 98.539  104.958 117.804 1.00 60.37  ? 150 PHE R CD1 1 
ATOM 6902 C CD2 . PHE E 5 203 ? 97.972  103.559 115.973 1.00 67.29  ? 150 PHE R CD2 1 
ATOM 6903 C CE1 . PHE E 5 203 ? 97.316  105.581 117.710 1.00 60.97  ? 150 PHE R CE1 1 
ATOM 6904 C CE2 . PHE E 5 203 ? 96.746  104.177 115.877 1.00 62.10  ? 150 PHE R CE2 1 
ATOM 6905 C CZ  . PHE E 5 203 ? 96.419  105.188 116.745 1.00 60.29  ? 150 PHE R CZ  1 
ATOM 6906 N N   . ILE E 5 204 ? 103.192 102.434 116.356 1.00 70.25  ? 151 ILE R N   1 
ATOM 6907 C CA  . ILE E 5 204 ? 104.359 101.756 116.906 1.00 75.21  ? 151 ILE R CA  1 
ATOM 6908 C C   . ILE E 5 204 ? 105.642 102.541 116.677 1.00 75.75  ? 151 ILE R C   1 
ATOM 6909 O O   . ILE E 5 204 ? 106.623 102.336 117.400 1.00 75.52  ? 151 ILE R O   1 
ATOM 6910 C CB  . ILE E 5 204 ? 104.478 100.333 116.331 1.00 75.86  ? 151 ILE R CB  1 
ATOM 6911 C CG1 . ILE E 5 204 ? 105.328 99.465  117.255 1.00 76.69  ? 151 ILE R CG1 1 
ATOM 6912 C CG2 . ILE E 5 204 ? 105.086 100.364 114.942 1.00 76.66  ? 151 ILE R CG2 1 
ATOM 6913 C CD1 . ILE E 5 204 ? 104.804 99.404  118.672 1.00 73.70  ? 151 ILE R CD1 1 
ATOM 6914 N N   . ILE E 5 205 ? 105.671 103.436 115.694 1.00 81.17  ? 152 ILE R N   1 
ATOM 6915 C CA  . ILE E 5 205 ? 106.852 104.265 115.493 1.00 79.61  ? 152 ILE R CA  1 
ATOM 6916 C C   . ILE E 5 205 ? 106.788 105.525 116.352 1.00 83.08  ? 152 ILE R C   1 
ATOM 6917 O O   . ILE E 5 205 ? 107.829 106.042 116.766 1.00 84.87  ? 152 ILE R O   1 
ATOM 6918 C CB  . ILE E 5 205 ? 107.035 104.611 114.005 1.00 80.49  ? 152 ILE R CB  1 
ATOM 6919 C CG1 . ILE E 5 205 ? 108.430 105.187 113.760 1.00 80.89  ? 152 ILE R CG1 1 
ATOM 6920 C CG2 . ILE E 5 205 ? 105.974 105.590 113.534 1.00 78.65  ? 152 ILE R CG2 1 
ATOM 6921 C CD1 . ILE E 5 205 ? 108.701 105.526 112.314 1.00 81.50  ? 152 ILE R CD1 1 
ATOM 6922 N N   . ASN E 5 206 ? 105.584 106.024 116.639 1.00 77.51  ? 153 ASN R N   1 
ATOM 6923 C CA  . ASN E 5 206 ? 105.448 107.153 117.550 1.00 71.85  ? 153 ASN R CA  1 
ATOM 6924 C C   . ASN E 5 206 ? 105.670 106.727 118.993 1.00 73.19  ? 153 ASN R C   1 
ATOM 6925 O O   . ASN E 5 206 ? 106.281 107.463 119.775 1.00 79.51  ? 153 ASN R O   1 
ATOM 6926 C CB  . ASN E 5 206 ? 104.075 107.797 117.387 1.00 71.54  ? 153 ASN R CB  1 
ATOM 6927 C CG  . ASN E 5 206 ? 103.939 108.543 116.083 1.00 76.19  ? 153 ASN R CG  1 
ATOM 6928 O OD1 . ASN E 5 206 ? 104.082 109.763 116.037 1.00 79.25  ? 153 ASN R OD1 1 
ATOM 6929 N ND2 . ASN E 5 206 ? 103.673 107.812 115.009 1.00 75.85  ? 153 ASN R ND2 1 
ATOM 6930 N N   . LEU E 5 207 ? 105.179 105.543 119.366 1.00 74.22  ? 154 LEU R N   1 
ATOM 6931 C CA  . LEU E 5 207 ? 105.409 105.045 120.717 1.00 72.31  ? 154 LEU R CA  1 
ATOM 6932 C C   . LEU E 5 207 ? 106.896 104.882 120.990 1.00 78.21  ? 154 LEU R C   1 
ATOM 6933 O O   . LEU E 5 207 ? 107.362 105.138 122.106 1.00 85.04  ? 154 LEU R O   1 
ATOM 6934 C CB  . LEU E 5 207 ? 104.679 103.719 120.924 1.00 76.83  ? 154 LEU R CB  1 
ATOM 6935 C CG  . LEU E 5 207 ? 104.833 103.072 122.300 1.00 76.26  ? 154 LEU R CG  1 
ATOM 6936 C CD1 . LEU E 5 207 ? 104.253 103.965 123.378 1.00 74.83  ? 154 LEU R CD1 1 
ATOM 6937 C CD2 . LEU E 5 207 ? 104.175 101.706 122.326 1.00 78.76  ? 154 LEU R CD2 1 
ATOM 6938 N N   . SER E 5 208 ? 107.658 104.456 119.982 1.00 85.69  ? 155 SER R N   1 
ATOM 6939 C CA  . SER E 5 208 ? 109.103 104.356 120.143 1.00 85.08  ? 155 SER R CA  1 
ATOM 6940 C C   . SER E 5 208 ? 109.755 105.730 120.206 1.00 87.85  ? 155 SER R C   1 
ATOM 6941 O O   . SER E 5 208 ? 110.767 105.900 120.893 1.00 94.30  ? 155 SER R O   1 
ATOM 6942 C CB  . SER E 5 208 ? 109.702 103.536 119.003 1.00 86.26  ? 155 SER R CB  1 
ATOM 6943 O OG  . SER E 5 208 ? 109.137 102.239 118.961 1.00 89.54  ? 155 SER R OG  1 
ATOM 6944 N N   . VAL E 5 209 ? 109.199 106.714 119.498 1.00 84.29  ? 156 VAL R N   1 
ATOM 6945 C CA  . VAL E 5 209 ? 109.742 108.069 119.551 1.00 85.77  ? 156 VAL R CA  1 
ATOM 6946 C C   . VAL E 5 209 ? 109.585 108.653 120.948 1.00 85.33  ? 156 VAL R C   1 
ATOM 6947 O O   . VAL E 5 209 ? 110.533 109.204 121.519 1.00 83.68  ? 156 VAL R O   1 
ATOM 6948 C CB  . VAL E 5 209 ? 109.070 108.957 118.489 1.00 83.44  ? 156 VAL R CB  1 
ATOM 6949 C CG1 . VAL E 5 209 ? 109.278 110.423 118.814 1.00 83.81  ? 156 VAL R CG1 1 
ATOM 6950 C CG2 . VAL E 5 209 ? 109.624 108.644 117.113 1.00 83.55  ? 156 VAL R CG2 1 
ATOM 6951 N N   . VAL E 5 210 ? 108.387 108.533 121.525 1.00 84.70  ? 157 VAL R N   1 
ATOM 6952 C CA  . VAL E 5 210 ? 108.152 109.057 122.867 1.00 81.67  ? 157 VAL R CA  1 
ATOM 6953 C C   . VAL E 5 210 ? 108.988 108.305 123.890 1.00 83.20  ? 157 VAL R C   1 
ATOM 6954 O O   . VAL E 5 210 ? 109.540 108.903 124.821 1.00 89.56  ? 157 VAL R O   1 
ATOM 6955 C CB  . VAL E 5 210 ? 106.658 108.990 123.213 1.00 79.48  ? 157 VAL R CB  1 
ATOM 6956 C CG1 . VAL E 5 210 ? 106.406 109.690 124.524 1.00 81.53  ? 157 VAL R CG1 1 
ATOM 6957 C CG2 . VAL E 5 210 ? 105.836 109.602 122.111 1.00 83.35  ? 157 VAL R CG2 1 
ATOM 6958 N N   . ASP E 5 211 ? 109.078 106.983 123.750 1.00 88.70  ? 158 ASP R N   1 
ATOM 6959 C CA  . ASP E 5 211 ? 109.922 106.203 124.645 1.00 92.19  ? 158 ASP R CA  1 
ATOM 6960 C C   . ASP E 5 211 ? 111.386 106.594 124.496 1.00 96.79  ? 158 ASP R C   1 
ATOM 6961 O O   . ASP E 5 211 ? 112.128 106.638 125.483 1.00 99.66  ? 158 ASP R O   1 
ATOM 6962 C CB  . ASP E 5 211 ? 109.731 104.711 124.378 1.00 96.84  ? 158 ASP R CB  1 
ATOM 6963 C CG  . ASP E 5 211 ? 108.375 104.209 124.830 1.00 99.21  ? 158 ASP R CG  1 
ATOM 6964 O OD1 . ASP E 5 211 ? 107.635 104.988 125.462 1.00 98.84  ? 158 ASP R OD1 1 
ATOM 6965 O OD2 . ASP E 5 211 ? 108.049 103.036 124.551 1.00 100.33 ? 158 ASP R OD2 1 
ATOM 6966 N N   . LEU E 5 212 ? 111.820 106.876 123.266 1.00 99.39  ? 159 LEU R N   1 
ATOM 6967 C CA  . LEU E 5 212 ? 113.196 107.312 123.050 1.00 99.07  ? 159 LEU R CA  1 
ATOM 6968 C C   . LEU E 5 212 ? 113.460 108.656 123.719 1.00 101.20 ? 159 LEU R C   1 
ATOM 6969 O O   . LEU E 5 212 ? 114.524 108.863 124.313 1.00 100.62 ? 159 LEU R O   1 
ATOM 6970 C CB  . LEU E 5 212 ? 113.494 107.381 121.554 1.00 97.69  ? 159 LEU R CB  1 
ATOM 6971 C CG  . LEU E 5 212 ? 114.961 107.521 121.156 1.00 100.24 ? 159 LEU R CG  1 
ATOM 6972 C CD1 . LEU E 5 212 ? 115.756 106.327 121.651 1.00 98.32  ? 159 LEU R CD1 1 
ATOM 6973 C CD2 . LEU E 5 212 ? 115.088 107.661 119.651 1.00 100.30 ? 159 LEU R CD2 1 
ATOM 6974 N N   . LEU E 5 213 ? 112.500 109.582 123.636 1.00 100.62 ? 160 LEU R N   1 
ATOM 6975 C CA  . LEU E 5 213 ? 112.641 110.858 124.332 1.00 98.28  ? 160 LEU R CA  1 
ATOM 6976 C C   . LEU E 5 213 ? 112.703 110.656 125.839 1.00 98.10  ? 160 LEU R C   1 
ATOM 6977 O O   . LEU E 5 213 ? 113.482 111.320 126.533 1.00 99.76  ? 160 LEU R O   1 
ATOM 6978 C CB  . LEU E 5 213 ? 111.486 111.790 123.970 1.00 94.92  ? 160 LEU R CB  1 
ATOM 6979 C CG  . LEU E 5 213 ? 111.371 112.222 122.509 1.00 95.56  ? 160 LEU R CG  1 
ATOM 6980 C CD1 . LEU E 5 213 ? 110.189 113.155 122.326 1.00 95.14  ? 160 LEU R CD1 1 
ATOM 6981 C CD2 . LEU E 5 213 ? 112.655 112.885 122.049 1.00 97.86  ? 160 LEU R CD2 1 
ATOM 6982 N N   . PHE E 5 214 ? 111.884 109.743 126.364 1.00 103.09 ? 161 PHE R N   1 
ATOM 6983 C CA  . PHE E 5 214 ? 111.892 109.465 127.794 1.00 101.71 ? 161 PHE R CA  1 
ATOM 6984 C C   . PHE E 5 214 ? 113.211 108.852 128.245 1.00 106.39 ? 161 PHE R C   1 
ATOM 6985 O O   . PHE E 5 214 ? 113.579 108.976 129.417 1.00 110.41 ? 161 PHE R O   1 
ATOM 6986 C CB  . PHE E 5 214 ? 110.727 108.543 128.148 1.00 102.68 ? 161 PHE R CB  1 
ATOM 6987 C CG  . PHE E 5 214 ? 110.488 108.400 129.620 1.00 104.50 ? 161 PHE R CG  1 
ATOM 6988 C CD1 . PHE E 5 214 ? 109.793 109.371 130.317 1.00 104.84 ? 161 PHE R CD1 1 
ATOM 6989 C CD2 . PHE E 5 214 ? 110.947 107.291 130.305 1.00 105.63 ? 161 PHE R CD2 1 
ATOM 6990 C CE1 . PHE E 5 214 ? 109.566 109.242 131.671 1.00 105.14 ? 161 PHE R CE1 1 
ATOM 6991 C CE2 . PHE E 5 214 ? 110.723 107.156 131.659 1.00 106.74 ? 161 PHE R CE2 1 
ATOM 6992 C CZ  . PHE E 5 214 ? 110.033 108.133 132.343 1.00 106.60 ? 161 PHE R CZ  1 
ATOM 6993 N N   . LEU E 5 215 ? 113.932 108.192 127.340 1.00 112.43 ? 162 LEU R N   1 
ATOM 6994 C CA  . LEU E 5 215 ? 115.215 107.593 127.684 1.00 114.59 ? 162 LEU R CA  1 
ATOM 6995 C C   . LEU E 5 215 ? 116.385 108.538 127.458 1.00 116.19 ? 162 LEU R C   1 
ATOM 6996 O O   . LEU E 5 215 ? 117.387 108.452 128.177 1.00 116.84 ? 162 LEU R O   1 
ATOM 6997 C CB  . LEU E 5 215 ? 115.435 106.309 126.881 1.00 114.47 ? 162 LEU R CB  1 
ATOM 6998 C CG  . LEU E 5 215 ? 114.452 105.174 127.162 1.00 114.47 ? 162 LEU R CG  1 
ATOM 6999 C CD1 . LEU E 5 215 ? 114.721 104.002 126.241 1.00 114.89 ? 162 LEU R CD1 1 
ATOM 7000 C CD2 . LEU E 5 215 ? 114.532 104.743 128.616 1.00 113.12 ? 162 LEU R CD2 1 
ATOM 7001 N N   . LEU E 5 216 ? 116.287 109.434 126.473 1.00 120.22 ? 163 LEU R N   1 
ATOM 7002 C CA  . LEU E 5 216 ? 117.359 110.397 126.245 1.00 120.47 ? 163 LEU R CA  1 
ATOM 7003 C C   . LEU E 5 216 ? 117.508 111.353 127.420 1.00 122.08 ? 163 LEU R C   1 
ATOM 7004 O O   . LEU E 5 216 ? 118.616 111.822 127.699 1.00 123.05 ? 163 LEU R O   1 
ATOM 7005 C CB  . LEU E 5 216 ? 117.107 111.174 124.954 1.00 119.08 ? 163 LEU R CB  1 
ATOM 7006 C CG  . LEU E 5 216 ? 117.289 110.391 123.653 1.00 118.68 ? 163 LEU R CG  1 
ATOM 7007 C CD1 . LEU E 5 216 ? 117.015 111.279 122.450 1.00 117.80 ? 163 LEU R CD1 1 
ATOM 7008 C CD2 . LEU E 5 216 ? 118.684 109.790 123.579 1.00 118.80 ? 163 LEU R CD2 1 
ATOM 7009 N N   . GLY E 5 217 ? 116.414 111.653 128.114 1.00 133.03 ? 164 GLY R N   1 
ATOM 7010 C CA  . GLY E 5 217 ? 116.455 112.501 129.284 1.00 132.79 ? 164 GLY R CA  1 
ATOM 7011 C C   . GLY E 5 217 ? 116.871 111.817 130.563 1.00 134.75 ? 164 GLY R C   1 
ATOM 7012 O O   . GLY E 5 217 ? 116.936 112.470 131.607 1.00 135.26 ? 164 GLY R O   1 
ATOM 7013 N N   . MET E 5 218 ? 117.143 110.512 130.518 1.00 140.91 ? 165 MET R N   1 
ATOM 7014 C CA  . MET E 5 218 ? 117.565 109.802 131.725 1.00 142.31 ? 165 MET R CA  1 
ATOM 7015 C C   . MET E 5 218 ? 118.880 110.321 132.296 1.00 143.95 ? 165 MET R C   1 
ATOM 7016 O O   . MET E 5 218 ? 118.930 110.588 133.510 1.00 144.95 ? 165 MET R O   1 
ATOM 7017 C CB  . MET E 5 218 ? 117.637 108.298 131.445 1.00 141.01 ? 165 MET R CB  1 
ATOM 7018 C CG  . MET E 5 218 ? 117.939 107.466 132.681 1.00 140.94 ? 165 MET R CG  1 
ATOM 7019 S SD  . MET E 5 218 ? 118.441 105.777 132.310 1.00 145.45 ? 165 MET R SD  1 
ATOM 7020 C CE  . MET E 5 218 ? 117.049 105.214 131.337 1.00 142.44 ? 165 MET R CE  1 
ATOM 7021 N N   . PRO E 5 219 ? 119.963 110.481 131.522 1.00 149.13 ? 166 PRO R N   1 
ATOM 7022 C CA  . PRO E 5 219 ? 121.209 110.980 132.130 1.00 148.37 ? 166 PRO R CA  1 
ATOM 7023 C C   . PRO E 5 219 ? 121.064 112.348 132.770 1.00 148.66 ? 166 PRO R C   1 
ATOM 7024 O O   . PRO E 5 219 ? 121.716 112.619 133.786 1.00 148.73 ? 166 PRO R O   1 
ATOM 7025 C CB  . PRO E 5 219 ? 122.191 111.007 130.950 1.00 147.82 ? 166 PRO R CB  1 
ATOM 7026 C CG  . PRO E 5 219 ? 121.334 111.050 129.739 1.00 148.20 ? 166 PRO R CG  1 
ATOM 7027 C CD  . PRO E 5 219 ? 120.140 110.222 130.082 1.00 147.87 ? 166 PRO R CD  1 
ATOM 7028 N N   . PHE E 5 220 ? 120.220 113.218 132.213 1.00 151.92 ? 167 PHE R N   1 
ATOM 7029 C CA  . PHE E 5 220 ? 119.970 114.519 132.818 1.00 151.60 ? 167 PHE R CA  1 
ATOM 7030 C C   . PHE E 5 220 ? 119.113 114.424 134.072 1.00 152.10 ? 167 PHE R C   1 
ATOM 7031 O O   . PHE E 5 220 ? 118.992 115.418 134.795 1.00 153.14 ? 167 PHE R O   1 
ATOM 7032 C CB  . PHE E 5 220 ? 119.304 115.455 131.807 1.00 150.85 ? 167 PHE R CB  1 
ATOM 7033 C CG  . PHE E 5 220 ? 120.122 115.693 130.570 1.00 151.92 ? 167 PHE R CG  1 
ATOM 7034 C CD1 . PHE E 5 220 ? 121.085 116.687 130.542 1.00 151.63 ? 167 PHE R CD1 1 
ATOM 7035 C CD2 . PHE E 5 220 ? 119.929 114.923 129.436 1.00 151.92 ? 167 PHE R CD2 1 
ATOM 7036 C CE1 . PHE E 5 220 ? 121.840 116.909 129.405 1.00 151.71 ? 167 PHE R CE1 1 
ATOM 7037 C CE2 . PHE E 5 220 ? 120.681 115.139 128.296 1.00 151.65 ? 167 PHE R CE2 1 
ATOM 7038 C CZ  . PHE E 5 220 ? 121.638 116.134 128.281 1.00 151.91 ? 167 PHE R CZ  1 
ATOM 7039 N N   . MET E 5 221 ? 118.519 113.262 134.345 1.00 151.79 ? 168 MET R N   1 
ATOM 7040 C CA  . MET E 5 221 ? 117.675 113.079 135.514 1.00 152.27 ? 168 MET R CA  1 
ATOM 7041 C C   . MET E 5 221 ? 118.251 112.115 136.540 1.00 151.97 ? 168 MET R C   1 
ATOM 7042 O O   . MET E 5 221 ? 117.682 111.992 137.630 1.00 153.66 ? 168 MET R O   1 
ATOM 7043 C CB  . MET E 5 221 ? 116.281 112.589 135.093 1.00 152.52 ? 168 MET R CB  1 
ATOM 7044 C CG  . MET E 5 221 ? 115.436 113.641 134.394 1.00 153.46 ? 168 MET R CG  1 
ATOM 7045 S SD  . MET E 5 221 ? 115.000 115.017 135.476 1.00 158.03 ? 168 MET R SD  1 
ATOM 7046 C CE  . MET E 5 221 ? 114.060 114.169 136.743 1.00 152.08 ? 168 MET R CE  1 
ATOM 7047 N N   . ILE E 5 222 ? 119.347 111.427 136.231 1.00 158.01 ? 169 ILE R N   1 
ATOM 7048 C CA  . ILE E 5 222 ? 119.942 110.488 137.171 1.00 159.63 ? 169 ILE R CA  1 
ATOM 7049 C C   . ILE E 5 222 ? 121.234 111.005 137.789 1.00 159.54 ? 169 ILE R C   1 
ATOM 7050 O O   . ILE E 5 222 ? 121.648 110.482 138.835 1.00 158.87 ? 169 ILE R O   1 
ATOM 7051 C CB  . ILE E 5 222 ? 120.186 109.114 136.516 1.00 159.13 ? 169 ILE R CB  1 
ATOM 7052 C CG1 . ILE E 5 222 ? 121.187 109.241 135.367 1.00 158.75 ? 169 ILE R CG1 1 
ATOM 7053 C CG2 . ILE E 5 222 ? 118.877 108.520 136.032 1.00 158.89 ? 169 ILE R CG2 1 
ATOM 7054 C CD1 . ILE E 5 222 ? 121.500 107.931 134.683 1.00 158.73 ? 169 ILE R CD1 1 
ATOM 7055 N N   . HIS E 5 223 ? 121.881 112.010 137.192 1.00 163.55 ? 170 HIS R N   1 
ATOM 7056 C CA  . HIS E 5 223 ? 123.100 112.544 137.786 1.00 163.84 ? 170 HIS R CA  1 
ATOM 7057 C C   . HIS E 5 223 ? 122.825 113.276 139.091 1.00 163.90 ? 170 HIS R C   1 
ATOM 7058 O O   . HIS E 5 223 ? 123.757 113.498 139.871 1.00 163.35 ? 170 HIS R O   1 
ATOM 7059 C CB  . HIS E 5 223 ? 123.809 113.478 136.804 1.00 163.83 ? 170 HIS R CB  1 
ATOM 7060 C CG  . HIS E 5 223 ? 123.236 114.860 136.761 1.00 164.11 ? 170 HIS R CG  1 
ATOM 7061 N ND1 . HIS E 5 223 ? 122.026 115.147 136.168 1.00 164.94 ? 170 HIS R ND1 1 
ATOM 7062 C CD2 . HIS E 5 223 ? 123.712 116.036 137.233 1.00 164.02 ? 170 HIS R CD2 1 
ATOM 7063 C CE1 . HIS E 5 223 ? 121.779 116.440 136.280 1.00 164.75 ? 170 HIS R CE1 1 
ATOM 7064 N NE2 . HIS E 5 223 ? 122.787 117.003 136.922 1.00 164.30 ? 170 HIS R NE2 1 
ATOM 7065 N N   . GLN E 5 224 ? 121.574 113.652 139.344 1.00 166.77 ? 171 GLN R N   1 
ATOM 7066 C CA  . GLN E 5 224 ? 121.177 114.272 140.599 1.00 167.66 ? 171 GLN R CA  1 
ATOM 7067 C C   . GLN E 5 224 ? 120.673 113.259 141.617 1.00 167.71 ? 171 GLN R C   1 
ATOM 7068 O O   . GLN E 5 224 ? 120.193 113.657 142.683 1.00 167.92 ? 171 GLN R O   1 
ATOM 7069 C CB  . GLN E 5 224 ? 120.097 115.326 140.350 1.00 166.67 ? 171 GLN R CB  1 
ATOM 7070 C CG  . GLN E 5 224 ? 118.761 114.747 139.919 1.00 165.85 ? 171 GLN R CG  1 
ATOM 7071 C CD  . GLN E 5 224 ? 117.651 115.778 139.924 1.00 166.57 ? 171 GLN R CD  1 
ATOM 7072 O OE1 . GLN E 5 224 ? 117.901 116.974 140.073 1.00 167.37 ? 171 GLN R OE1 1 
ATOM 7073 N NE2 . GLN E 5 224 ? 116.415 115.319 139.767 1.00 165.77 ? 171 GLN R NE2 1 
ATOM 7074 N N   . LEU E 5 225 ? 120.754 111.965 141.311 1.00 171.30 ? 172 LEU R N   1 
ATOM 7075 C CA  . LEU E 5 225 ? 120.256 110.933 142.206 1.00 171.65 ? 172 LEU R CA  1 
ATOM 7076 C C   . LEU E 5 225 ? 121.322 109.965 142.692 1.00 171.14 ? 172 LEU R C   1 
ATOM 7077 O O   . LEU E 5 225 ? 121.085 109.269 143.685 1.00 171.00 ? 172 LEU R O   1 
ATOM 7078 C CB  . LEU E 5 225 ? 119.133 110.132 141.528 1.00 171.96 ? 172 LEU R CB  1 
ATOM 7079 C CG  . LEU E 5 225 ? 117.951 110.952 141.005 1.00 171.50 ? 172 LEU R CG  1 
ATOM 7080 C CD1 . LEU E 5 225 ? 116.926 110.055 140.328 1.00 170.85 ? 172 LEU R CD1 1 
ATOM 7081 C CD2 . LEU E 5 225 ? 117.309 111.754 142.128 1.00 170.51 ? 172 LEU R CD2 1 
ATOM 7082 N N   . MET E 5 226 ? 122.475 109.897 142.034 1.00 158.98 ? 173 MET R N   1 
ATOM 7083 C CA  . MET E 5 226 ? 123.500 108.921 142.382 1.00 158.68 ? 173 MET R CA  1 
ATOM 7084 C C   . MET E 5 226 ? 124.817 109.549 142.809 1.00 158.39 ? 173 MET R C   1 
ATOM 7085 O O   . MET E 5 226 ? 125.440 109.067 143.759 1.00 157.19 ? 173 MET R O   1 
ATOM 7086 C CB  . MET E 5 226 ? 123.745 107.970 141.198 1.00 157.96 ? 173 MET R CB  1 
ATOM 7087 C CG  . MET E 5 226 ? 124.052 108.669 139.883 1.00 159.26 ? 173 MET R CG  1 
ATOM 7088 S SD  . MET E 5 226 ? 124.052 107.548 138.471 1.00 162.19 ? 173 MET R SD  1 
ATOM 7089 C CE  . MET E 5 226 ? 124.425 108.684 137.137 1.00 157.84 ? 173 MET R CE  1 
ATOM 7090 N N   . GLY E 5 227 ? 125.262 110.609 142.139 1.00 169.88 ? 174 GLY R N   1 
ATOM 7091 C CA  . GLY E 5 227 ? 126.582 111.147 142.399 1.00 169.99 ? 174 GLY R CA  1 
ATOM 7092 C C   . GLY E 5 227 ? 126.647 112.144 143.537 1.00 170.21 ? 174 GLY R C   1 
ATOM 7093 O O   . GLY E 5 227 ? 127.350 111.918 144.527 1.00 169.81 ? 174 GLY R O   1 
ATOM 7094 N N   . ASN E 5 228 ? 125.918 113.253 143.412 1.00 168.90 ? 175 ASN R N   1 
ATOM 7095 C CA  . ASN E 5 228 ? 125.972 114.311 144.418 1.00 168.93 ? 175 ASN R CA  1 
ATOM 7096 C C   . ASN E 5 228 ? 124.619 114.876 144.819 1.00 169.24 ? 175 ASN R C   1 
ATOM 7097 O O   . ASN E 5 228 ? 124.527 115.480 145.893 1.00 168.27 ? 175 ASN R O   1 
ATOM 7098 C CB  . ASN E 5 228 ? 126.860 115.463 143.933 1.00 167.39 ? 175 ASN R CB  1 
ATOM 7099 N N   . GLY E 5 229 ? 123.570 114.710 144.021 1.00 175.26 ? 176 GLY R N   1 
ATOM 7100 C CA  . GLY E 5 229 ? 122.283 115.304 144.336 1.00 174.83 ? 176 GLY R CA  1 
ATOM 7101 C C   . GLY E 5 229 ? 122.271 116.816 144.263 1.00 175.13 ? 176 GLY R C   1 
ATOM 7102 O O   . GLY E 5 229 ? 121.614 117.468 145.085 1.00 174.01 ? 176 GLY R O   1 
ATOM 7103 N N   . VAL E 5 230 ? 122.984 117.391 143.297 1.00 173.43 ? 177 VAL R N   1 
ATOM 7104 C CA  . VAL E 5 230 ? 123.048 118.835 143.102 1.00 173.51 ? 177 VAL R CA  1 
ATOM 7105 C C   . VAL E 5 230 ? 122.755 119.131 141.639 1.00 172.87 ? 177 VAL R C   1 
ATOM 7106 O O   . VAL E 5 230 ? 123.323 118.492 140.747 1.00 172.67 ? 177 VAL R O   1 
ATOM 7107 C CB  . VAL E 5 230 ? 124.421 119.409 143.506 1.00 173.43 ? 177 VAL R CB  1 
ATOM 7108 C CG1 . VAL E 5 230 ? 124.464 120.909 143.257 1.00 171.92 ? 177 VAL R CG1 1 
ATOM 7109 C CG2 . VAL E 5 230 ? 124.723 119.099 144.964 1.00 172.68 ? 177 VAL R CG2 1 
ATOM 7110 N N   . TRP E 5 231 ? 121.872 120.097 141.393 1.00 164.87 ? 178 TRP R N   1 
ATOM 7111 C CA  . TRP E 5 231 ? 121.520 120.479 140.031 1.00 164.60 ? 178 TRP R CA  1 
ATOM 7112 C C   . TRP E 5 231 ? 122.541 121.479 139.503 1.00 164.17 ? 178 TRP R C   1 
ATOM 7113 O O   . TRP E 5 231 ? 122.712 122.561 140.074 1.00 162.87 ? 178 TRP R O   1 
ATOM 7114 C CB  . TRP E 5 231 ? 120.113 121.069 139.992 1.00 163.60 ? 178 TRP R CB  1 
ATOM 7115 C CG  . TRP E 5 231 ? 119.649 121.423 138.614 1.00 164.22 ? 178 TRP R CG  1 
ATOM 7116 C CD1 . TRP E 5 231 ? 119.713 122.647 138.018 1.00 164.06 ? 178 TRP R CD1 1 
ATOM 7117 C CD2 . TRP E 5 231 ? 119.052 120.540 137.657 1.00 164.66 ? 178 TRP R CD2 1 
ATOM 7118 N NE1 . TRP E 5 231 ? 119.190 122.583 136.749 1.00 165.01 ? 178 TRP R NE1 1 
ATOM 7119 C CE2 . TRP E 5 231 ? 118.777 121.300 136.503 1.00 164.09 ? 178 TRP R CE2 1 
ATOM 7120 C CE3 . TRP E 5 231 ? 118.722 119.182 137.663 1.00 164.49 ? 178 TRP R CE3 1 
ATOM 7121 C CZ2 . TRP E 5 231 ? 118.189 120.748 135.368 1.00 163.04 ? 178 TRP R CZ2 1 
ATOM 7122 C CZ3 . TRP E 5 231 ? 118.139 118.635 136.535 1.00 163.71 ? 178 TRP R CZ3 1 
ATOM 7123 C CH2 . TRP E 5 231 ? 117.879 119.417 135.404 1.00 163.19 ? 178 TRP R CH2 1 
ATOM 7124 N N   . HIS E 5 232 ? 123.218 121.119 138.413 1.00 166.04 ? 179 HIS R N   1 
ATOM 7125 C CA  . HIS E 5 232 ? 124.273 121.944 137.842 1.00 165.44 ? 179 HIS R CA  1 
ATOM 7126 C C   . HIS E 5 232 ? 123.849 122.665 136.571 1.00 165.53 ? 179 HIS R C   1 
ATOM 7127 O O   . HIS E 5 232 ? 124.670 123.369 135.974 1.00 164.62 ? 179 HIS R O   1 
ATOM 7128 C CB  . HIS E 5 232 ? 125.511 121.088 137.547 1.00 165.33 ? 179 HIS R CB  1 
ATOM 7129 C CG  . HIS E 5 232 ? 125.781 120.036 138.578 1.00 166.16 ? 179 HIS R CG  1 
ATOM 7130 N ND1 . HIS E 5 232 ? 126.409 120.308 139.774 1.00 166.31 ? 179 HIS R ND1 1 
ATOM 7131 C CD2 . HIS E 5 232 ? 125.517 118.708 138.585 1.00 165.67 ? 179 HIS R CD2 1 
ATOM 7132 C CE1 . HIS E 5 232 ? 126.514 119.194 140.477 1.00 165.71 ? 179 HIS R CE1 1 
ATOM 7133 N NE2 . HIS E 5 232 ? 125.980 118.209 139.778 1.00 165.63 ? 179 HIS R NE2 1 
ATOM 7134 N N   . PHE E 5 233 ? 122.600 122.512 136.138 1.00 167.30 ? 180 PHE R N   1 
ATOM 7135 C CA  . PHE E 5 233 ? 122.142 123.075 134.875 1.00 166.77 ? 180 PHE R CA  1 
ATOM 7136 C C   . PHE E 5 233 ? 121.387 124.387 135.039 1.00 166.89 ? 180 PHE R C   1 
ATOM 7137 O O   . PHE E 5 233 ? 120.909 124.937 134.043 1.00 166.17 ? 180 PHE R O   1 
ATOM 7138 C CB  . PHE E 5 233 ? 121.262 122.061 134.139 1.00 166.71 ? 180 PHE R CB  1 
ATOM 7139 C CG  . PHE E 5 233 ? 121.971 120.781 133.798 1.00 167.98 ? 180 PHE R CG  1 
ATOM 7140 C CD1 . PHE E 5 233 ? 123.329 120.778 133.524 1.00 167.56 ? 180 PHE R CD1 1 
ATOM 7141 C CD2 . PHE E 5 233 ? 121.281 119.581 133.760 1.00 167.99 ? 180 PHE R CD2 1 
ATOM 7142 C CE1 . PHE E 5 233 ? 123.984 119.602 133.213 1.00 167.18 ? 180 PHE R CE1 1 
ATOM 7143 C CE2 . PHE E 5 233 ? 121.931 118.402 133.450 1.00 167.59 ? 180 PHE R CE2 1 
ATOM 7144 C CZ  . PHE E 5 233 ? 123.284 118.412 133.176 1.00 167.22 ? 180 PHE R CZ  1 
ATOM 7145 N N   . GLY E 5 234 ? 121.265 124.899 136.260 1.00 173.53 ? 181 GLY R N   1 
ATOM 7146 C CA  . GLY E 5 234 ? 120.608 126.170 136.478 1.00 173.36 ? 181 GLY R CA  1 
ATOM 7147 C C   . GLY E 5 234 ? 119.095 126.061 136.504 1.00 172.89 ? 181 GLY R C   1 
ATOM 7148 O O   . GLY E 5 234 ? 118.500 125.000 136.317 1.00 173.78 ? 181 GLY R O   1 
ATOM 7149 N N   . GLU E 5 235 ? 118.462 127.212 136.743 1.00 159.83 ? 182 GLU R N   1 
ATOM 7150 C CA  . GLU E 5 235 ? 117.007 127.259 136.833 1.00 160.03 ? 182 GLU R CA  1 
ATOM 7151 C C   . GLU E 5 235 ? 116.347 127.149 135.464 1.00 159.65 ? 182 GLU R C   1 
ATOM 7152 O O   . GLU E 5 235 ? 115.226 126.639 135.359 1.00 159.45 ? 182 GLU R O   1 
ATOM 7153 C CB  . GLU E 5 235 ? 116.567 128.546 137.531 1.00 159.84 ? 182 GLU R CB  1 
ATOM 7154 C CG  . GLU E 5 235 ? 115.073 128.638 137.792 1.00 159.44 ? 182 GLU R CG  1 
ATOM 7155 C CD  . GLU E 5 235 ? 114.682 129.930 138.480 1.00 159.63 ? 182 GLU R CD  1 
ATOM 7156 O OE1 . GLU E 5 235 ? 115.579 130.757 138.747 1.00 159.35 ? 182 GLU R OE1 1 
ATOM 7157 O OE2 . GLU E 5 235 ? 113.478 130.119 138.753 1.00 159.22 ? 182 GLU R OE2 1 
ATOM 7158 N N   . THR E 5 236 ? 117.018 127.622 134.410 1.00 160.14 ? 183 THR R N   1 
ATOM 7159 C CA  . THR E 5 236 ? 116.417 127.596 133.080 1.00 160.89 ? 183 THR R CA  1 
ATOM 7160 C C   . THR E 5 236 ? 116.152 126.170 132.615 1.00 159.54 ? 183 THR R C   1 
ATOM 7161 O O   . THR E 5 236 ? 115.087 125.879 132.057 1.00 157.62 ? 183 THR R O   1 
ATOM 7162 C CB  . THR E 5 236 ? 117.319 128.322 132.082 1.00 160.54 ? 183 THR R CB  1 
ATOM 7163 O OG1 . THR E 5 236 ? 118.593 127.668 132.025 1.00 159.95 ? 183 THR R OG1 1 
ATOM 7164 C CG2 . THR E 5 236 ? 117.518 129.771 132.500 1.00 159.94 ? 183 THR R CG2 1 
ATOM 7165 N N   . MET E 5 237 ? 117.106 125.266 132.833 1.00 150.25 ? 184 MET R N   1 
ATOM 7166 C CA  . MET E 5 237 ? 116.926 123.878 132.430 1.00 149.75 ? 184 MET R CA  1 
ATOM 7167 C C   . MET E 5 237 ? 116.019 123.104 133.377 1.00 149.16 ? 184 MET R C   1 
ATOM 7168 O O   . MET E 5 237 ? 115.476 122.068 132.981 1.00 149.85 ? 184 MET R O   1 
ATOM 7169 C CB  . MET E 5 237 ? 118.282 123.176 132.333 1.00 150.42 ? 184 MET R CB  1 
ATOM 7170 C CG  . MET E 5 237 ? 119.243 123.815 131.344 1.00 150.72 ? 184 MET R CG  1 
ATOM 7171 S SD  . MET E 5 237 ? 118.649 123.743 129.644 1.00 151.14 ? 184 MET R SD  1 
ATOM 7172 C CE  . MET E 5 237 ? 118.590 121.972 129.384 1.00 148.60 ? 184 MET R CE  1 
ATOM 7173 N N   . CYS E 5 238 ? 115.849 123.579 134.612 1.00 150.51 ? 185 CYS R N   1 
ATOM 7174 C CA  . CYS E 5 238 ? 115.032 122.854 135.580 1.00 150.77 ? 185 CYS R CA  1 
ATOM 7175 C C   . CYS E 5 238 ? 113.578 122.774 135.133 1.00 150.70 ? 185 CYS R C   1 
ATOM 7176 O O   . CYS E 5 238 ? 112.949 121.714 135.228 1.00 151.34 ? 185 CYS R O   1 
ATOM 7177 C CB  . CYS E 5 238 ? 115.139 123.513 136.954 1.00 151.10 ? 185 CYS R CB  1 
ATOM 7178 S SG  . CYS E 5 238 ? 114.032 122.829 138.206 1.00 153.97 ? 185 CYS R SG  1 
ATOM 7179 N N   . THR E 5 239 ? 113.025 123.885 134.644 1.00 148.98 ? 186 THR R N   1 
ATOM 7180 C CA  . THR E 5 239 ? 111.637 123.881 134.196 1.00 148.49 ? 186 THR R CA  1 
ATOM 7181 C C   . THR E 5 239 ? 111.482 123.138 132.874 1.00 147.99 ? 186 THR R C   1 
ATOM 7182 O O   . THR E 5 239 ? 110.487 122.436 132.664 1.00 148.17 ? 186 THR R O   1 
ATOM 7183 C CB  . THR E 5 239 ? 111.119 125.314 134.069 1.00 149.03 ? 186 THR R CB  1 
ATOM 7184 O OG1 . THR E 5 239 ? 111.296 125.998 135.315 1.00 149.85 ? 186 THR R OG1 1 
ATOM 7185 C CG2 . THR E 5 239 ? 109.643 125.318 133.706 1.00 147.28 ? 186 THR R CG2 1 
ATOM 7186 N N   . LEU E 5 240 ? 112.455 123.279 131.972 1.00 144.08 ? 187 LEU R N   1 
ATOM 7187 C CA  . LEU E 5 240 ? 112.344 122.646 130.662 1.00 142.84 ? 187 LEU R CA  1 
ATOM 7188 C C   . LEU E 5 240 ? 112.441 121.128 130.766 1.00 143.40 ? 187 LEU R C   1 
ATOM 7189 O O   . LEU E 5 240 ? 111.619 120.406 130.193 1.00 144.27 ? 187 LEU R O   1 
ATOM 7190 C CB  . LEU E 5 240 ? 113.421 123.187 129.723 1.00 144.55 ? 187 LEU R CB  1 
ATOM 7191 C CG  . LEU E 5 240 ? 113.426 122.585 128.317 1.00 143.94 ? 187 LEU R CG  1 
ATOM 7192 C CD1 . LEU E 5 240 ? 112.104 122.854 127.616 1.00 142.28 ? 187 LEU R CD1 1 
ATOM 7193 C CD2 . LEU E 5 240 ? 114.591 123.123 127.501 1.00 143.51 ? 187 LEU R CD2 1 
ATOM 7194 N N   . ILE E 5 241 ? 113.443 120.625 131.492 1.00 138.68 ? 188 ILE R N   1 
ATOM 7195 C CA  . ILE E 5 241 ? 113.632 119.180 131.581 1.00 137.83 ? 188 ILE R CA  1 
ATOM 7196 C C   . ILE E 5 241 ? 112.473 118.531 132.326 1.00 138.50 ? 188 ILE R C   1 
ATOM 7197 O O   . ILE E 5 241 ? 111.974 117.475 131.921 1.00 139.42 ? 188 ILE R O   1 
ATOM 7198 C CB  . ILE E 5 241 ? 114.985 118.853 132.237 1.00 137.09 ? 188 ILE R CB  1 
ATOM 7199 C CG1 . ILE E 5 241 ? 116.133 119.303 131.333 1.00 139.45 ? 188 ILE R CG1 1 
ATOM 7200 C CG2 . ILE E 5 241 ? 115.094 117.366 132.530 1.00 136.06 ? 188 ILE R CG2 1 
ATOM 7201 C CD1 . ILE E 5 241 ? 117.501 118.925 131.851 1.00 140.45 ? 188 ILE R CD1 1 
ATOM 7202 N N   . THR E 5 242 ? 112.024 119.148 133.422 1.00 134.34 ? 189 THR R N   1 
ATOM 7203 C CA  . THR E 5 242 ? 110.910 118.585 134.177 1.00 133.16 ? 189 THR R CA  1 
ATOM 7204 C C   . THR E 5 242 ? 109.645 118.530 133.331 1.00 131.70 ? 189 THR R C   1 
ATOM 7205 O O   . THR E 5 242 ? 108.917 117.530 133.354 1.00 133.82 ? 189 THR R O   1 
ATOM 7206 C CB  . THR E 5 242 ? 110.670 119.398 135.449 1.00 134.39 ? 189 THR R CB  1 
ATOM 7207 O OG1 . THR E 5 242 ? 111.866 119.414 136.238 1.00 134.21 ? 189 THR R OG1 1 
ATOM 7208 C CG2 . THR E 5 242 ? 109.540 118.792 136.265 1.00 133.89 ? 189 THR R CG2 1 
ATOM 7209 N N   . ALA E 5 243 ? 109.366 119.593 132.576 1.00 122.77 ? 190 ALA R N   1 
ATOM 7210 C CA  . ALA E 5 243 ? 108.223 119.570 131.670 1.00 124.52 ? 190 ALA R CA  1 
ATOM 7211 C C   . ALA E 5 243 ? 108.434 118.570 130.540 1.00 124.71 ? 190 ALA R C   1 
ATOM 7212 O O   . ALA E 5 243 ? 107.496 117.874 130.136 1.00 124.85 ? 190 ALA R O   1 
ATOM 7213 C CB  . ALA E 5 243 ? 107.966 120.968 131.110 1.00 126.78 ? 190 ALA R CB  1 
ATOM 7214 N N   . MET E 5 244 ? 109.657 118.495 130.010 1.00 119.44 ? 191 MET R N   1 
ATOM 7215 C CA  . MET E 5 244 ? 109.949 117.534 128.951 1.00 118.63 ? 191 MET R CA  1 
ATOM 7216 C C   . MET E 5 244 ? 109.837 116.101 129.456 1.00 118.22 ? 191 MET R C   1 
ATOM 7217 O O   . MET E 5 244 ? 109.303 115.231 128.759 1.00 118.45 ? 191 MET R O   1 
ATOM 7218 C CB  . MET E 5 244 ? 111.343 117.792 128.381 1.00 118.20 ? 191 MET R CB  1 
ATOM 7219 C CG  . MET E 5 244 ? 111.744 116.857 127.255 1.00 118.21 ? 191 MET R CG  1 
ATOM 7220 S SD  . MET E 5 244 ? 110.683 117.021 125.809 1.00 124.59 ? 191 MET R SD  1 
ATOM 7221 C CE  . MET E 5 244 ? 111.469 115.870 124.686 1.00 120.75 ? 191 MET R CE  1 
ATOM 7222 N N   . ASP E 5 245 ? 110.342 115.837 130.662 1.00 114.36 ? 192 ASP R N   1 
ATOM 7223 C CA  . ASP E 5 245 ? 110.273 114.489 131.217 1.00 110.75 ? 192 ASP R CA  1 
ATOM 7224 C C   . ASP E 5 245 ? 108.833 114.072 131.491 1.00 110.20 ? 192 ASP R C   1 
ATOM 7225 O O   . ASP E 5 245 ? 108.458 112.921 131.243 1.00 114.57 ? 192 ASP R O   1 
ATOM 7226 C CB  . ASP E 5 245 ? 111.108 114.406 132.493 1.00 112.88 ? 192 ASP R CB  1 
ATOM 7227 C CG  . ASP E 5 245 ? 111.084 113.028 133.113 1.00 114.50 ? 192 ASP R CG  1 
ATOM 7228 O OD1 . ASP E 5 245 ? 111.688 112.104 132.530 1.00 116.15 ? 192 ASP R OD1 1 
ATOM 7229 O OD2 . ASP E 5 245 ? 110.461 112.868 134.183 1.00 114.02 ? 192 ASP R OD2 1 
ATOM 7230 N N   . ALA E 5 246 ? 108.016 114.988 132.010 1.00 98.27  ? 193 ALA R N   1 
ATOM 7231 C CA  . ALA E 5 246 ? 106.620 114.662 132.278 1.00 97.48  ? 193 ALA R CA  1 
ATOM 7232 C C   . ALA E 5 246 ? 105.848 114.421 130.988 1.00 96.65  ? 193 ALA R C   1 
ATOM 7233 O O   . ALA E 5 246 ? 104.964 113.559 130.941 1.00 100.01 ? 193 ALA R O   1 
ATOM 7234 C CB  . ALA E 5 246 ? 105.966 115.773 133.095 1.00 100.43 ? 193 ALA R CB  1 
ATOM 7235 N N   . ASN E 5 247 ? 106.159 115.178 129.934 1.00 90.41  ? 194 ASN R N   1 
ATOM 7236 C CA  . ASN E 5 247 ? 105.451 115.006 128.670 1.00 90.03  ? 194 ASN R CA  1 
ATOM 7237 C C   . ASN E 5 247 ? 105.717 113.634 128.068 1.00 88.73  ? 194 ASN R C   1 
ATOM 7238 O O   . ASN E 5 247 ? 104.816 113.017 127.490 1.00 91.34  ? 194 ASN R O   1 
ATOM 7239 C CB  . ASN E 5 247 ? 105.851 116.102 127.687 1.00 93.64  ? 194 ASN R CB  1 
ATOM 7240 C CG  . ASN E 5 247 ? 105.069 116.034 126.395 1.00 91.81  ? 194 ASN R CG  1 
ATOM 7241 O OD1 . ASN E 5 247 ? 105.547 115.505 125.393 1.00 91.27  ? 194 ASN R OD1 1 
ATOM 7242 N ND2 . ASN E 5 247 ? 103.853 116.564 126.413 1.00 91.41  ? 194 ASN R ND2 1 
ATOM 7243 N N   . SER E 5 248 ? 106.952 113.144 128.180 1.00 89.94  ? 195 SER R N   1 
ATOM 7244 C CA  . SER E 5 248 ? 107.276 111.833 127.629 1.00 89.74  ? 195 SER R CA  1 
ATOM 7245 C C   . SER E 5 248 ? 106.524 110.725 128.355 1.00 90.16  ? 195 SER R C   1 
ATOM 7246 O O   . SER E 5 248 ? 106.090 109.751 127.731 1.00 95.19  ? 195 SER R O   1 
ATOM 7247 C CB  . SER E 5 248 ? 108.782 111.597 127.694 1.00 92.41  ? 195 SER R CB  1 
ATOM 7248 O OG  . SER E 5 248 ? 109.479 112.579 126.950 1.00 90.64  ? 195 SER R OG  1 
ATOM 7249 N N   . GLN E 5 249 ? 106.368 110.848 129.674 1.00 88.66  ? 196 GLN R N   1 
ATOM 7250 C CA  . GLN E 5 249 ? 105.621 109.843 130.425 1.00 85.63  ? 196 GLN R CA  1 
ATOM 7251 C C   . GLN E 5 249 ? 104.144 109.854 130.050 1.00 86.65  ? 196 GLN R C   1 
ATOM 7252 O O   . GLN E 5 249 ? 103.542 108.796 129.836 1.00 92.33  ? 196 GLN R O   1 
ATOM 7253 C CB  . GLN E 5 249 ? 105.796 110.073 131.924 1.00 85.78  ? 196 GLN R CB  1 
ATOM 7254 C CG  . GLN E 5 249 ? 104.967 109.144 132.786 1.00 88.69  ? 196 GLN R CG  1 
ATOM 7255 C CD  . GLN E 5 249 ? 105.145 109.413 134.264 1.00 91.36  ? 196 GLN R CD  1 
ATOM 7256 O OE1 . GLN E 5 249 ? 105.925 110.279 134.660 1.00 87.57  ? 196 GLN R OE1 1 
ATOM 7257 N NE2 . GLN E 5 249 ? 104.421 108.670 135.090 1.00 92.53  ? 196 GLN R NE2 1 
ATOM 7258 N N   . PHE E 5 250 ? 103.542 111.042 129.966 1.00 78.02  ? 197 PHE R N   1 
ATOM 7259 C CA  . PHE E 5 250 ? 102.123 111.129 129.636 1.00 73.64  ? 197 PHE R CA  1 
ATOM 7260 C C   . PHE E 5 250 ? 101.856 110.724 128.192 1.00 79.91  ? 197 PHE R C   1 
ATOM 7261 O O   . PHE E 5 250 ? 100.858 110.053 127.908 1.00 86.30  ? 197 PHE R O   1 
ATOM 7262 C CB  . PHE E 5 250 ? 101.607 112.542 129.898 1.00 78.08  ? 197 PHE R CB  1 
ATOM 7263 C CG  . PHE E 5 250 ? 101.199 112.787 131.321 1.00 83.72  ? 197 PHE R CG  1 
ATOM 7264 C CD1 . PHE E 5 250 ? 102.148 112.960 132.311 1.00 84.62  ? 197 PHE R CD1 1 
ATOM 7265 C CD2 . PHE E 5 250 ? 99.862  112.864 131.665 1.00 81.90  ? 197 PHE R CD2 1 
ATOM 7266 C CE1 . PHE E 5 250 ? 101.772 113.191 133.619 1.00 81.63  ? 197 PHE R CE1 1 
ATOM 7267 C CE2 . PHE E 5 250 ? 99.480  113.097 132.971 1.00 82.60  ? 197 PHE R CE2 1 
ATOM 7268 C CZ  . PHE E 5 250 ? 100.436 113.260 133.947 1.00 84.06  ? 197 PHE R CZ  1 
ATOM 7269 N N   . THR E 5 251 ? 102.721 111.134 127.263 1.00 81.84  ? 198 THR R N   1 
ATOM 7270 C CA  . THR E 5 251 ? 102.472 110.846 125.853 1.00 77.09  ? 198 THR R CA  1 
ATOM 7271 C C   . THR E 5 251 ? 102.580 109.357 125.558 1.00 78.39  ? 198 THR R C   1 
ATOM 7272 O O   . THR E 5 251 ? 101.731 108.798 124.855 1.00 83.28  ? 198 THR R O   1 
ATOM 7273 C CB  . THR E 5 251 ? 103.442 111.626 124.970 1.00 80.60  ? 198 THR R CB  1 
ATOM 7274 O OG1 . THR E 5 251 ? 103.431 113.007 125.346 1.00 88.86  ? 198 THR R OG1 1 
ATOM 7275 C CG2 . THR E 5 251 ? 103.047 111.497 123.511 1.00 78.25  ? 198 THR R CG2 1 
ATOM 7276 N N   . SER E 5 252 ? 103.614 108.696 126.083 1.00 74.46  ? 199 SER R N   1 
ATOM 7277 C CA  . SER E 5 252 ? 103.786 107.272 125.819 1.00 72.08  ? 199 SER R CA  1 
ATOM 7278 C C   . SER E 5 252 ? 102.640 106.466 126.410 1.00 70.94  ? 199 SER R C   1 
ATOM 7279 O O   . SER E 5 252 ? 102.194 105.478 125.817 1.00 79.67  ? 199 SER R O   1 
ATOM 7280 C CB  . SER E 5 252 ? 105.124 106.789 126.373 1.00 70.47  ? 199 SER R CB  1 
ATOM 7281 O OG  . SER E 5 252 ? 105.188 106.967 127.775 1.00 75.94  ? 199 SER R OG  1 
ATOM 7282 N N   . THR E 5 253 ? 102.156 106.868 127.584 1.00 62.12  ? 200 THR R N   1 
ATOM 7283 C CA  . THR E 5 253 ? 101.014 106.185 128.179 1.00 65.00  ? 200 THR R CA  1 
ATOM 7284 C C   . THR E 5 253 ? 99.758  106.388 127.343 1.00 66.99  ? 200 THR R C   1 
ATOM 7285 O O   . THR E 5 253 ? 98.959  105.460 127.176 1.00 70.61  ? 200 THR R O   1 
ATOM 7286 C CB  . THR E 5 253 ? 100.798 106.680 129.606 1.00 64.98  ? 200 THR R CB  1 
ATOM 7287 O OG1 . THR E 5 253 ? 101.997 106.487 130.365 1.00 66.02  ? 200 THR R OG1 1 
ATOM 7288 C CG2 . THR E 5 253 ? 99.678  105.917 130.258 1.00 65.77  ? 200 THR R CG2 1 
ATOM 7289 N N   . TYR E 5 254 ? 99.563  107.597 126.813 1.00 73.29  ? 201 TYR R N   1 
ATOM 7290 C CA  . TYR E 5 254 ? 98.387  107.867 125.993 1.00 70.06  ? 201 TYR R CA  1 
ATOM 7291 C C   . TYR E 5 254 ? 98.483  107.187 124.634 1.00 69.69  ? 201 TYR R C   1 
ATOM 7292 O O   . TYR E 5 254 ? 97.471  106.728 124.093 1.00 70.22  ? 201 TYR R O   1 
ATOM 7293 C CB  . TYR E 5 254 ? 98.202  109.373 125.827 1.00 69.77  ? 201 TYR R CB  1 
ATOM 7294 C CG  . TYR E 5 254 ? 97.752  110.068 127.086 1.00 74.04  ? 201 TYR R CG  1 
ATOM 7295 C CD1 . TYR E 5 254 ? 97.074  109.374 128.078 1.00 69.35  ? 201 TYR R CD1 1 
ATOM 7296 C CD2 . TYR E 5 254 ? 98.003  111.417 127.285 1.00 76.27  ? 201 TYR R CD2 1 
ATOM 7297 C CE1 . TYR E 5 254 ? 96.658  110.004 129.231 1.00 74.94  ? 201 TYR R CE1 1 
ATOM 7298 C CE2 . TYR E 5 254 ? 97.591  112.056 128.435 1.00 76.43  ? 201 TYR R CE2 1 
ATOM 7299 C CZ  . TYR E 5 254 ? 96.919  111.346 129.404 1.00 79.60  ? 201 TYR R CZ  1 
ATOM 7300 O OH  . TYR E 5 254 ? 96.507  111.979 130.553 1.00 79.99  ? 201 TYR R OH  1 
ATOM 7301 N N   . ILE E 5 255 ? 99.684  107.126 124.057 1.00 64.01  ? 202 ILE R N   1 
ATOM 7302 C CA  . ILE E 5 255 ? 99.857  106.414 122.796 1.00 59.89  ? 202 ILE R CA  1 
ATOM 7303 C C   . ILE E 5 255 ? 99.620  104.924 122.991 1.00 65.73  ? 202 ILE R C   1 
ATOM 7304 O O   . ILE E 5 255 ? 99.000  104.265 122.150 1.00 69.03  ? 202 ILE R O   1 
ATOM 7305 C CB  . ILE E 5 255 ? 101.248 106.701 122.204 1.00 57.37  ? 202 ILE R CB  1 
ATOM 7306 C CG1 . ILE E 5 255 ? 101.311 108.136 121.680 1.00 63.04  ? 202 ILE R CG1 1 
ATOM 7307 C CG2 . ILE E 5 255 ? 101.579 105.715 121.099 1.00 62.23  ? 202 ILE R CG2 1 
ATOM 7308 C CD1 . ILE E 5 255 ? 102.588 108.460 120.949 1.00 68.18  ? 202 ILE R CD1 1 
ATOM 7309 N N   . LEU E 5 256 ? 100.108 104.370 124.102 1.00 67.24  ? 203 LEU R N   1 
ATOM 7310 C CA  . LEU E 5 256 ? 99.846  102.968 124.406 1.00 57.27  ? 203 LEU R CA  1 
ATOM 7311 C C   . LEU E 5 256 ? 98.357  102.720 124.606 1.00 58.23  ? 203 LEU R C   1 
ATOM 7312 O O   . LEU E 5 256 ? 97.826  101.694 124.167 1.00 66.30  ? 203 LEU R O   1 
ATOM 7313 C CB  . LEU E 5 256 ? 100.637 102.553 125.645 1.00 57.18  ? 203 LEU R CB  1 
ATOM 7314 C CG  . LEU E 5 256 ? 100.635 101.075 126.026 1.00 64.95  ? 203 LEU R CG  1 
ATOM 7315 C CD1 . LEU E 5 256 ? 101.286 100.251 124.935 1.00 64.41  ? 203 LEU R CD1 1 
ATOM 7316 C CD2 . LEU E 5 256 ? 101.355 100.874 127.344 1.00 62.49  ? 203 LEU R CD2 1 
ATOM 7317 N N   . THR E 5 257 ? 97.665  103.648 125.270 1.00 56.10  ? 204 THR R N   1 
ATOM 7318 C CA  . THR E 5 257 ? 96.221  103.522 125.429 1.00 51.52  ? 204 THR R CA  1 
ATOM 7319 C C   . THR E 5 257 ? 95.501  103.629 124.091 1.00 54.86  ? 204 THR R C   1 
ATOM 7320 O O   . THR E 5 257 ? 94.537  102.898 123.840 1.00 63.60  ? 204 THR R O   1 
ATOM 7321 C CB  . THR E 5 257 ? 95.703  104.583 126.396 1.00 58.14  ? 204 THR R CB  1 
ATOM 7322 O OG1 . THR E 5 257 ? 96.410  104.481 127.636 1.00 66.02  ? 204 THR R OG1 1 
ATOM 7323 C CG2 . THR E 5 257 ? 94.222  104.387 126.651 1.00 57.26  ? 204 THR R CG2 1 
ATOM 7324 N N   . ALA E 5 258 ? 95.945  104.540 123.223 1.00 62.47  ? 205 ALA R N   1 
ATOM 7325 C CA  . ALA E 5 258 ? 95.331  104.651 121.904 1.00 62.07  ? 205 ALA R CA  1 
ATOM 7326 C C   . ALA E 5 258 ? 95.662  103.451 121.033 1.00 58.40  ? 205 ALA R C   1 
ATOM 7327 O O   . ALA E 5 258 ? 94.840  103.036 120.210 1.00 60.41  ? 205 ALA R O   1 
ATOM 7328 C CB  . ALA E 5 258 ? 95.778  105.940 121.219 1.00 61.23  ? 205 ALA R CB  1 
ATOM 7329 N N   . MET E 5 259 ? 96.858  102.887 121.192 1.00 57.04  ? 206 MET R N   1 
ATOM 7330 C CA  . MET E 5 259 ? 97.228  101.691 120.452 1.00 50.93  ? 206 MET R CA  1 
ATOM 7331 C C   . MET E 5 259 ? 96.484  100.460 120.950 1.00 55.14  ? 206 MET R C   1 
ATOM 7332 O O   . MET E 5 259 ? 96.394  99.469  120.221 1.00 65.91  ? 206 MET R O   1 
ATOM 7333 C CB  . MET E 5 259 ? 98.738  101.479 120.545 1.00 54.82  ? 206 MET R CB  1 
ATOM 7334 C CG  . MET E 5 259 ? 99.309  100.547 119.506 1.00 59.68  ? 206 MET R CG  1 
ATOM 7335 S SD  . MET E 5 259 ? 101.094 100.403 119.669 1.00 68.82  ? 206 MET R SD  1 
ATOM 7336 C CE  . MET E 5 259 ? 101.210 99.692  121.304 1.00 62.00  ? 206 MET R CE  1 
ATOM 7337 N N   . ALA E 5 260 ? 95.951  100.501 122.172 1.00 56.88  ? 207 ALA R N   1 
ATOM 7338 C CA  . ALA E 5 260 ? 95.149  99.393  122.678 1.00 51.17  ? 207 ALA R CA  1 
ATOM 7339 C C   . ALA E 5 260 ? 93.706  99.479  122.201 1.00 51.41  ? 207 ALA R C   1 
ATOM 7340 O O   . ALA E 5 260 ? 93.082  98.452  121.921 1.00 61.73  ? 207 ALA R O   1 
ATOM 7341 C CB  . ALA E 5 260 ? 95.201  99.358  124.205 1.00 46.70  ? 207 ALA R CB  1 
ATOM 7342 N N   . ILE E 5 261 ? 93.155  100.692 122.119 1.00 45.56  ? 208 ILE R N   1 
ATOM 7343 C CA  . ILE E 5 261 ? 91.821  100.867 121.558 1.00 49.85  ? 208 ILE R CA  1 
ATOM 7344 C C   . ILE E 5 261 ? 91.834  100.603 120.061 1.00 57.51  ? 208 ILE R C   1 
ATOM 7345 O O   . ILE E 5 261 ? 90.846  100.119 119.498 1.00 61.29  ? 208 ILE R O   1 
ATOM 7346 C CB  . ILE E 5 261 ? 91.283  102.271 121.883 1.00 52.46  ? 208 ILE R CB  1 
ATOM 7347 C CG1 . ILE E 5 261 ? 91.298  102.506 123.392 1.00 56.59  ? 208 ILE R CG1 1 
ATOM 7348 C CG2 . ILE E 5 261 ? 89.873  102.446 121.346 1.00 52.17  ? 208 ILE R CG2 1 
ATOM 7349 C CD1 . ILE E 5 261 ? 90.758  103.854 123.802 1.00 58.54  ? 208 ILE R CD1 1 
ATOM 7350 N N   . ASP E 5 262 ? 92.941  100.923 119.390 1.00 56.23  ? 209 ASP R N   1 
ATOM 7351 C CA  . ASP E 5 262 ? 93.060  100.625 117.968 1.00 50.60  ? 209 ASP R CA  1 
ATOM 7352 C C   . ASP E 5 262 ? 92.970  99.127  117.711 1.00 58.59  ? 209 ASP R C   1 
ATOM 7353 O O   . ASP E 5 262 ? 92.313  98.692  116.759 1.00 63.96  ? 209 ASP R O   1 
ATOM 7354 C CB  . ASP E 5 262 ? 94.375  101.182 117.429 1.00 52.55  ? 209 ASP R CB  1 
ATOM 7355 C CG  . ASP E 5 262 ? 94.633  100.782 115.996 1.00 59.09  ? 209 ASP R CG  1 
ATOM 7356 O OD1 . ASP E 5 262 ? 93.958  101.321 115.098 1.00 65.55  ? 209 ASP R OD1 1 
ATOM 7357 O OD2 . ASP E 5 262 ? 95.512  99.926  115.767 1.00 56.04  ? 209 ASP R OD2 1 
ATOM 7358 N N   . ARG E 5 263 ? 93.621  98.323  118.551 1.00 48.11  ? 210 ARG R N   1 
ATOM 7359 C CA  . ARG E 5 263 ? 93.545  96.876  118.400 1.00 39.27  ? 210 ARG R CA  1 
ATOM 7360 C C   . ARG E 5 263 ? 92.172  96.337  118.769 1.00 45.73  ? 210 ARG R C   1 
ATOM 7361 O O   . ARG E 5 263 ? 91.745  95.315  118.223 1.00 54.91  ? 210 ARG R O   1 
ATOM 7362 C CB  . ARG E 5 263 ? 94.628  96.215  119.245 1.00 44.00  ? 210 ARG R CB  1 
ATOM 7363 C CG  . ARG E 5 263 ? 96.018  96.490  118.733 1.00 46.58  ? 210 ARG R CG  1 
ATOM 7364 C CD  . ARG E 5 263 ? 97.072  96.194  119.767 1.00 50.54  ? 210 ARG R CD  1 
ATOM 7365 N NE  . ARG E 5 263 ? 98.404  96.299  119.189 1.00 44.93  ? 210 ARG R NE  1 
ATOM 7366 C CZ  . ARG E 5 263 ? 99.523  96.338  119.894 1.00 43.54  ? 210 ARG R CZ  1 
ATOM 7367 N NH1 . ARG E 5 263 ? 99.508  96.300  121.214 1.00 47.55  ? 210 ARG R NH1 1 
ATOM 7368 N NH2 . ARG E 5 263 ? 100.687 96.418  119.258 1.00 52.89  ? 210 ARG R NH2 1 
ATOM 7369 N N   . TYR E 5 264 ? 91.476  96.992  119.698 1.00 51.24  ? 211 TYR R N   1 
ATOM 7370 C CA  . TYR E 5 264 ? 90.108  96.593  120.009 1.00 42.61  ? 211 TYR R CA  1 
ATOM 7371 C C   . TYR E 5 264 ? 89.190  96.794  118.812 1.00 47.79  ? 211 TYR R C   1 
ATOM 7372 O O   . TYR E 5 264 ? 88.377  95.921  118.490 1.00 57.98  ? 211 TYR R O   1 
ATOM 7373 C CB  . TYR E 5 264 ? 89.596  97.382  121.211 1.00 43.67  ? 211 TYR R CB  1 
ATOM 7374 C CG  . TYR E 5 264 ? 88.119  97.220  121.472 1.00 46.90  ? 211 TYR R CG  1 
ATOM 7375 C CD1 . TYR E 5 264 ? 87.639  96.148  122.206 1.00 44.80  ? 211 TYR R CD1 1 
ATOM 7376 C CD2 . TYR E 5 264 ? 87.203  98.140  120.983 1.00 52.09  ? 211 TYR R CD2 1 
ATOM 7377 C CE1 . TYR E 5 264 ? 86.292  95.997  122.447 1.00 50.60  ? 211 TYR R CE1 1 
ATOM 7378 C CE2 . TYR E 5 264 ? 85.854  97.995  121.216 1.00 49.35  ? 211 TYR R CE2 1 
ATOM 7379 C CZ  . TYR E 5 264 ? 85.405  96.922  121.949 1.00 55.46  ? 211 TYR R CZ  1 
ATOM 7380 O OH  . TYR E 5 264 ? 84.059  96.775  122.186 1.00 58.68  ? 211 TYR R OH  1 
ATOM 7381 N N   . LEU E 5 265 ? 89.304  97.941  118.140 1.00 50.78  ? 212 LEU R N   1 
ATOM 7382 C CA  . LEU E 5 265 ? 88.447  98.208  116.990 1.00 55.57  ? 212 LEU R CA  1 
ATOM 7383 C C   . LEU E 5 265 ? 88.813  97.323  115.807 1.00 54.11  ? 212 LEU R C   1 
ATOM 7384 O O   . LEU E 5 265 ? 87.931  96.861  115.077 1.00 56.73  ? 212 LEU R O   1 
ATOM 7385 C CB  . LEU E 5 265 ? 88.527  99.684  116.606 1.00 52.48  ? 212 LEU R CB  1 
ATOM 7386 C CG  . LEU E 5 265 ? 88.036  100.674 117.662 1.00 49.41  ? 212 LEU R CG  1 
ATOM 7387 C CD1 . LEU E 5 265 ? 88.147  102.095 117.150 1.00 51.86  ? 212 LEU R CD1 1 
ATOM 7388 C CD2 . LEU E 5 265 ? 86.609  100.362 118.071 1.00 52.73  ? 212 LEU R CD2 1 
ATOM 7389 N N   . ALA E 5 266 ? 90.105  97.073  115.604 1.00 53.13  ? 213 ALA R N   1 
ATOM 7390 C CA  . ALA E 5 266 ? 90.545  96.246  114.489 1.00 45.46  ? 213 ALA R CA  1 
ATOM 7391 C C   . ALA E 5 266 ? 90.160  94.784  114.646 1.00 50.68  ? 213 ALA R C   1 
ATOM 7392 O O   . ALA E 5 266 ? 90.229  94.037  113.666 1.00 57.74  ? 213 ALA R O   1 
ATOM 7393 C CB  . ALA E 5 266 ? 92.059  96.359  114.323 1.00 47.61  ? 213 ALA R CB  1 
ATOM 7394 N N   . THR E 5 267 ? 89.758  94.360  115.843 1.00 46.19  ? 214 THR R N   1 
ATOM 7395 C CA  . THR E 5 267 ? 89.440  92.967  116.127 1.00 40.10  ? 214 THR R CA  1 
ATOM 7396 C C   . THR E 5 267 ? 87.969  92.742  116.435 1.00 44.22  ? 214 THR R C   1 
ATOM 7397 O O   . THR E 5 267 ? 87.342  91.861  115.842 1.00 65.07  ? 214 THR R O   1 
ATOM 7398 C CB  . THR E 5 267 ? 90.294  92.469  117.300 1.00 52.68  ? 214 THR R CB  1 
ATOM 7399 O OG1 . THR E 5 267 ? 91.680  92.550  116.950 1.00 51.42  ? 214 THR R OG1 1 
ATOM 7400 C CG2 . THR E 5 267 ? 89.945  91.036  117.643 1.00 58.56  ? 214 THR R CG2 1 
ATOM 7401 N N   . VAL E 5 268 ? 87.397  93.511  117.361 1.00 48.19  ? 215 VAL R N   1 
ATOM 7402 C CA  . VAL E 5 268 ? 85.995  93.320  117.713 1.00 56.18  ? 215 VAL R CA  1 
ATOM 7403 C C   . VAL E 5 268 ? 85.059  93.936  116.680 1.00 56.00  ? 215 VAL R C   1 
ATOM 7404 O O   . VAL E 5 268 ? 83.915  93.486  116.545 1.00 63.29  ? 215 VAL R O   1 
ATOM 7405 C CB  . VAL E 5 268 ? 85.722  93.885  119.116 1.00 55.39  ? 215 VAL R CB  1 
ATOM 7406 C CG1 . VAL E 5 268 ? 84.334  93.494  119.596 1.00 56.59  ? 215 VAL R CG1 1 
ATOM 7407 C CG2 . VAL E 5 268 ? 86.769  93.381  120.086 1.00 54.81  ? 215 VAL R CG2 1 
ATOM 7408 N N   . HIS E 5 269 ? 85.516  94.936  115.932 1.00 53.29  ? 216 HIS R N   1 
ATOM 7409 C CA  . HIS E 5 269 ? 84.722  95.577  114.884 1.00 56.06  ? 216 HIS R CA  1 
ATOM 7410 C C   . HIS E 5 269 ? 85.539  95.601  113.600 1.00 58.74  ? 216 HIS R C   1 
ATOM 7411 O O   . HIS E 5 269 ? 85.959  96.665  113.134 1.00 58.69  ? 216 HIS R O   1 
ATOM 7412 C CB  . HIS E 5 269 ? 84.304  96.989  115.296 1.00 54.77  ? 216 HIS R CB  1 
ATOM 7413 C CG  . HIS E 5 269 ? 83.554  97.045  116.590 1.00 60.95  ? 216 HIS R CG  1 
ATOM 7414 N ND1 . HIS E 5 269 ? 82.220  96.715  116.691 1.00 61.51  ? 216 HIS R ND1 1 
ATOM 7415 C CD2 . HIS E 5 269 ? 83.950  97.395  117.836 1.00 61.23  ? 216 HIS R CD2 1 
ATOM 7416 C CE1 . HIS E 5 269 ? 81.827  96.858  117.944 1.00 59.25  ? 216 HIS R CE1 1 
ATOM 7417 N NE2 . HIS E 5 269 ? 82.858  97.270  118.659 1.00 62.76  ? 216 HIS R NE2 1 
ATOM 7418 N N   . PRO E 5 270 ? 85.768  94.436  112.989 1.00 51.08  ? 217 PRO R N   1 
ATOM 7419 C CA  . PRO E 5 270 ? 86.657  94.388  111.820 1.00 44.85  ? 217 PRO R CA  1 
ATOM 7420 C C   . PRO E 5 270 ? 86.047  94.976  110.564 1.00 52.43  ? 217 PRO R C   1 
ATOM 7421 O O   . PRO E 5 270 ? 86.790  95.293  109.628 1.00 52.16  ? 217 PRO R O   1 
ATOM 7422 C CB  . PRO E 5 270 ? 86.932  92.887  111.646 1.00 45.74  ? 217 PRO R CB  1 
ATOM 7423 C CG  . PRO E 5 270 ? 86.084  92.180  112.679 1.00 46.46  ? 217 PRO R CG  1 
ATOM 7424 C CD  . PRO E 5 270 ? 85.097  93.150  113.213 1.00 44.69  ? 217 PRO R CD  1 
ATOM 7425 N N   . ILE E 5 271 ? 84.730  95.126  110.508 1.00 62.55  ? 218 ILE R N   1 
ATOM 7426 C CA  . ILE E 5 271 ? 84.039  95.604  109.317 1.00 60.62  ? 218 ILE R CA  1 
ATOM 7427 C C   . ILE E 5 271 ? 83.667  97.075  109.437 1.00 60.50  ? 218 ILE R C   1 
ATOM 7428 O O   . ILE E 5 271 ? 83.894  97.858  108.515 1.00 62.83  ? 218 ILE R O   1 
ATOM 7429 C CB  . ILE E 5 271 ? 82.792  94.732  109.048 1.00 57.64  ? 218 ILE R CB  1 
ATOM 7430 C CG1 . ILE E 5 271 ? 83.156  93.248  109.082 1.00 56.13  ? 218 ILE R CG1 1 
ATOM 7431 C CG2 . ILE E 5 271 ? 82.166  95.094  107.715 1.00 56.08  ? 218 ILE R CG2 1 
ATOM 7432 C CD1 . ILE E 5 271 ? 84.187  92.850  108.061 1.00 56.64  ? 218 ILE R CD1 1 
ATOM 7433 N N   . SER E 5 272 ? 83.091  97.469  110.574 1.00 57.05  ? 219 SER R N   1 
ATOM 7434 C CA  . SER E 5 272 ? 82.636  98.845  110.737 1.00 57.51  ? 219 SER R CA  1 
ATOM 7435 C C   . SER E 5 272 ? 83.793  99.811  110.950 1.00 60.24  ? 219 SER R C   1 
ATOM 7436 O O   . SER E 5 272 ? 83.705  100.976 110.547 1.00 67.81  ? 219 SER R O   1 
ATOM 7437 C CB  . SER E 5 272 ? 81.655  98.938  111.903 1.00 56.65  ? 219 SER R CB  1 
ATOM 7438 O OG  . SER E 5 272 ? 82.272  98.545  113.114 1.00 62.01  ? 219 SER R OG  1 
ATOM 7439 N N   . SER E 5 273 ? 84.880  99.358  111.571 1.00 57.45  ? 220 SER R N   1 
ATOM 7440 C CA  . SER E 5 273 ? 85.993  100.245 111.877 1.00 59.92  ? 220 SER R CA  1 
ATOM 7441 C C   . SER E 5 273 ? 86.845  100.580 110.663 1.00 64.91  ? 220 SER R C   1 
ATOM 7442 O O   . SER E 5 273 ? 87.679  101.487 110.750 1.00 71.26  ? 220 SER R O   1 
ATOM 7443 C CB  . SER E 5 273 ? 86.879  99.626  112.956 1.00 63.30  ? 220 SER R CB  1 
ATOM 7444 O OG  . SER E 5 273 ? 87.428  98.401  112.508 1.00 67.06  ? 220 SER R OG  1 
ATOM 7445 N N   . THR E 5 274 ? 86.665  99.881  109.540 1.00 60.76  ? 221 THR R N   1 
ATOM 7446 C CA  . THR E 5 274 ? 87.428  100.207 108.341 1.00 62.96  ? 221 THR R CA  1 
ATOM 7447 C C   . THR E 5 274 ? 87.081  101.585 107.798 1.00 66.38  ? 221 THR R C   1 
ATOM 7448 O O   . THR E 5 274 ? 87.846  102.133 106.997 1.00 67.35  ? 221 THR R O   1 
ATOM 7449 C CB  . THR E 5 274 ? 87.190  99.157  107.256 1.00 61.18  ? 221 THR R CB  1 
ATOM 7450 O OG1 . THR E 5 274 ? 85.792  99.082  106.960 1.00 64.55  ? 221 THR R OG1 1 
ATOM 7451 C CG2 . THR E 5 274 ? 87.675  97.797  107.718 1.00 63.69  ? 221 THR R CG2 1 
ATOM 7452 N N   . LYS E 5 275 ? 85.950  102.156 108.217 1.00 67.43  ? 222 LYS R N   1 
ATOM 7453 C CA  . LYS E 5 275 ? 85.557  103.473 107.734 1.00 67.30  ? 222 LYS R CA  1 
ATOM 7454 C C   . LYS E 5 275 ? 86.453  104.572 108.288 1.00 71.75  ? 222 LYS R C   1 
ATOM 7455 O O   . LYS E 5 275 ? 86.689  105.574 107.605 1.00 76.19  ? 222 LYS R O   1 
ATOM 7456 C CB  . LYS E 5 275 ? 84.100  103.749 108.101 1.00 67.58  ? 222 LYS R CB  1 
ATOM 7457 C CG  . LYS E 5 275 ? 83.136  102.653 107.680 1.00 70.57  ? 222 LYS R CG  1 
ATOM 7458 C CD  . LYS E 5 275 ? 81.731  102.930 108.186 1.00 72.12  ? 222 LYS R CD  1 
ATOM 7459 C CE  . LYS E 5 275 ? 80.787  101.793 107.838 1.00 72.11  ? 222 LYS R CE  1 
ATOM 7460 N NZ  . LYS E 5 275 ? 79.418  102.024 108.377 1.00 70.54  ? 222 LYS R NZ  1 
ATOM 7461 N N   . PHE E 5 276 ? 86.959  104.414 109.514 1.00 62.03  ? 223 PHE R N   1 
ATOM 7462 C CA  . PHE E 5 276 ? 87.735  105.471 110.149 1.00 60.45  ? 223 PHE R CA  1 
ATOM 7463 C C   . PHE E 5 276 ? 89.088  105.008 110.677 1.00 62.84  ? 223 PHE R C   1 
ATOM 7464 O O   . PHE E 5 276 ? 89.753  105.774 111.382 1.00 69.06  ? 223 PHE R O   1 
ATOM 7465 C CB  . PHE E 5 276 ? 86.930  106.125 111.280 1.00 60.37  ? 223 PHE R CB  1 
ATOM 7466 C CG  . PHE E 5 276 ? 86.240  105.147 112.184 1.00 65.98  ? 223 PHE R CG  1 
ATOM 7467 C CD1 . PHE E 5 276 ? 86.903  104.592 113.263 1.00 66.67  ? 223 PHE R CD1 1 
ATOM 7468 C CD2 . PHE E 5 276 ? 84.918  104.799 111.964 1.00 66.77  ? 223 PHE R CD2 1 
ATOM 7469 C CE1 . PHE E 5 276 ? 86.265  103.696 114.100 1.00 68.68  ? 223 PHE R CE1 1 
ATOM 7470 C CE2 . PHE E 5 276 ? 84.275  103.905 112.795 1.00 67.86  ? 223 PHE R CE2 1 
ATOM 7471 C CZ  . PHE E 5 276 ? 84.949  103.352 113.865 1.00 68.61  ? 223 PHE R CZ  1 
ATOM 7472 N N   . ARG E 5 277 ? 89.519  103.789 110.362 1.00 63.79  ? 224 ARG R N   1 
ATOM 7473 C CA  . ARG E 5 277 ? 90.871  103.349 110.710 1.00 65.99  ? 224 ARG R CA  1 
ATOM 7474 C C   . ARG E 5 277 ? 91.815  103.591 109.533 1.00 66.58  ? 224 ARG R C   1 
ATOM 7475 O O   . ARG E 5 277 ? 92.463  102.687 109.008 1.00 66.22  ? 224 ARG R O   1 
ATOM 7476 C CB  . ARG E 5 277 ? 90.870  101.885 111.135 1.00 66.01  ? 224 ARG R CB  1 
ATOM 7477 C CG  . ARG E 5 277 ? 90.383  101.656 112.554 1.00 60.69  ? 224 ARG R CG  1 
ATOM 7478 C CD  . ARG E 5 277 ? 90.583  100.217 112.999 1.00 63.93  ? 224 ARG R CD  1 
ATOM 7479 N NE  . ARG E 5 277 ? 91.990  99.846  113.097 1.00 64.26  ? 224 ARG R NE  1 
ATOM 7480 C CZ  . ARG E 5 277 ? 92.643  99.140  112.185 1.00 67.70  ? 224 ARG R CZ  1 
ATOM 7481 N NH1 . ARG E 5 277 ? 92.047  98.717  111.083 1.00 65.38  ? 224 ARG R NH1 1 
ATOM 7482 N NH2 . ARG E 5 277 ? 93.923  98.845  112.386 1.00 61.34  ? 224 ARG R NH2 1 
ATOM 7483 N N   . LYS E 5 278 ? 91.879  104.846 109.129 1.00 72.84  ? 225 LYS R N   1 
ATOM 7484 C CA  . LYS E 5 278 ? 92.700  105.336 108.038 1.00 73.10  ? 225 LYS R CA  1 
ATOM 7485 C C   . LYS E 5 278 ? 94.003  105.918 108.568 1.00 72.48  ? 225 LYS R C   1 
ATOM 7486 O O   . LYS E 5 278 ? 94.060  106.397 109.704 1.00 75.70  ? 225 LYS R O   1 
ATOM 7487 C CB  . LYS E 5 278 ? 91.952  106.412 107.247 1.00 72.71  ? 225 LYS R CB  1 
ATOM 7488 C CG  . LYS E 5 278 ? 90.650  105.939 106.630 1.00 74.63  ? 225 LYS R CG  1 
ATOM 7489 C CD  . LYS E 5 278 ? 89.935  107.079 105.925 1.00 76.95  ? 225 LYS R CD  1 
ATOM 7490 C CE  . LYS E 5 278 ? 88.655  106.605 105.261 1.00 71.71  ? 225 LYS R CE  1 
ATOM 7491 N NZ  . LYS E 5 278 ? 87.936  107.720 104.588 1.00 69.24  ? 225 LYS R NZ  1 
ATOM 7492 N N   . PRO E 5 279 ? 95.071  105.878 107.769 1.00 72.84  ? 226 PRO R N   1 
ATOM 7493 C CA  . PRO E 5 279 ? 96.326  106.514 108.200 1.00 75.43  ? 226 PRO R CA  1 
ATOM 7494 C C   . PRO E 5 279 ? 96.189  108.005 108.450 1.00 75.48  ? 226 PRO R C   1 
ATOM 7495 O O   . PRO E 5 279 ? 96.910  108.550 109.294 1.00 75.81  ? 226 PRO R O   1 
ATOM 7496 C CB  . PRO E 5 279 ? 97.284  106.218 107.039 1.00 73.08  ? 226 PRO R CB  1 
ATOM 7497 C CG  . PRO E 5 279 ? 96.716  105.011 106.383 1.00 74.07  ? 226 PRO R CG  1 
ATOM 7498 C CD  . PRO E 5 279 ? 95.231  105.137 106.508 1.00 72.52  ? 226 PRO R CD  1 
ATOM 7499 N N   . SER E 5 280 ? 95.290  108.685 107.736 1.00 79.52  ? 227 SER R N   1 
ATOM 7500 C CA  . SER E 5 280 ? 95.073  110.105 107.984 1.00 76.20  ? 227 SER R CA  1 
ATOM 7501 C C   . SER E 5 280 ? 94.463  110.342 109.360 1.00 79.49  ? 227 SER R C   1 
ATOM 7502 O O   . SER E 5 280 ? 94.854  111.280 110.064 1.00 79.67  ? 227 SER R O   1 
ATOM 7503 C CB  . SER E 5 280 ? 94.180  110.696 106.894 1.00 78.46  ? 227 SER R CB  1 
ATOM 7504 O OG  . SER E 5 280 ? 92.912  110.066 106.879 1.00 77.60  ? 227 SER R OG  1 
ATOM 7505 N N   . VAL E 5 281 ? 93.501  109.507 109.759 1.00 75.04  ? 228 VAL R N   1 
ATOM 7506 C CA  . VAL E 5 281 ? 92.906  109.646 111.084 1.00 72.36  ? 228 VAL R CA  1 
ATOM 7507 C C   . VAL E 5 281 ? 93.921  109.299 112.165 1.00 70.82  ? 228 VAL R C   1 
ATOM 7508 O O   . VAL E 5 281 ? 93.940  109.915 113.237 1.00 72.31  ? 228 VAL R O   1 
ATOM 7509 C CB  . VAL E 5 281 ? 91.636  108.785 111.197 1.00 70.63  ? 228 VAL R CB  1 
ATOM 7510 C CG1 . VAL E 5 281 ? 90.984  108.980 112.554 1.00 67.91  ? 228 VAL R CG1 1 
ATOM 7511 C CG2 . VAL E 5 281 ? 90.661  109.136 110.087 1.00 72.77  ? 228 VAL R CG2 1 
ATOM 7512 N N   . ALA E 5 282 ? 94.778  108.308 111.905 1.00 67.55  ? 229 ALA R N   1 
ATOM 7513 C CA  . ALA E 5 282 ? 95.789  107.928 112.886 1.00 68.27  ? 229 ALA R CA  1 
ATOM 7514 C C   . ALA E 5 282 ? 96.752  109.075 113.163 1.00 73.88  ? 229 ALA R C   1 
ATOM 7515 O O   . ALA E 5 282 ? 97.124  109.317 114.316 1.00 76.79  ? 229 ALA R O   1 
ATOM 7516 C CB  . ALA E 5 282 ? 96.552  106.696 112.403 1.00 71.81  ? 229 ALA R CB  1 
ATOM 7517 N N   . THR E 5 283 ? 97.173  109.789 112.116 1.00 78.70  ? 230 THR R N   1 
ATOM 7518 C CA  . THR E 5 283 ? 98.029  110.955 112.314 1.00 76.86  ? 230 THR R CA  1 
ATOM 7519 C C   . THR E 5 283 ? 97.300  112.042 113.092 1.00 76.82  ? 230 THR R C   1 
ATOM 7520 O O   . THR E 5 283 ? 97.891  112.703 113.953 1.00 77.79  ? 230 THR R O   1 
ATOM 7521 C CB  . THR E 5 283 ? 98.515  111.491 110.968 1.00 77.15  ? 230 THR R CB  1 
ATOM 7522 O OG1 . THR E 5 283 ? 99.187  110.448 110.252 1.00 81.69  ? 230 THR R OG1 1 
ATOM 7523 C CG2 . THR E 5 283 ? 99.478  112.645 111.174 1.00 72.56  ? 230 THR R CG2 1 
ATOM 7524 N N   . LEU E 5 284 ? 96.013  112.243 112.801 1.00 74.47  ? 231 LEU R N   1 
ATOM 7525 C CA  . LEU E 5 284 ? 95.230  113.226 113.541 1.00 77.27  ? 231 LEU R CA  1 
ATOM 7526 C C   . LEU E 5 284 ? 95.114  112.845 115.011 1.00 83.56  ? 231 LEU R C   1 
ATOM 7527 O O   . LEU E 5 284 ? 95.211  113.706 115.893 1.00 83.22  ? 231 LEU R O   1 
ATOM 7528 C CB  . LEU E 5 284 ? 93.843  113.367 112.917 1.00 76.77  ? 231 LEU R CB  1 
ATOM 7529 C CG  . LEU E 5 284 ? 92.856  114.284 113.640 1.00 80.43  ? 231 LEU R CG  1 
ATOM 7530 C CD1 . LEU E 5 284 ? 93.357  115.718 113.641 1.00 79.64  ? 231 LEU R CD1 1 
ATOM 7531 C CD2 . LEU E 5 284 ? 91.475  114.193 113.013 1.00 77.55  ? 231 LEU R CD2 1 
ATOM 7532 N N   . VAL E 5 285 ? 94.900  111.558 115.292 1.00 79.84  ? 232 VAL R N   1 
ATOM 7533 C CA  . VAL E 5 285 ? 94.759  111.104 116.673 1.00 72.44  ? 232 VAL R CA  1 
ATOM 7534 C C   . VAL E 5 285 ? 96.059  111.291 117.443 1.00 68.37  ? 232 VAL R C   1 
ATOM 7535 O O   . VAL E 5 285 ? 96.055  111.771 118.582 1.00 76.38  ? 232 VAL R O   1 
ATOM 7536 C CB  . VAL E 5 285 ? 94.286  109.640 116.707 1.00 73.72  ? 232 VAL R CB  1 
ATOM 7537 C CG1 . VAL E 5 285 ? 94.416  109.075 118.107 1.00 71.90  ? 232 VAL R CG1 1 
ATOM 7538 C CG2 . VAL E 5 285 ? 92.845  109.543 116.235 1.00 75.12  ? 232 VAL R CG2 1 
ATOM 7539 N N   . ILE E 5 286 ? 97.190  110.918 116.841 1.00 68.41  ? 233 ILE R N   1 
ATOM 7540 C CA  . ILE E 5 286 ? 98.468  111.032 117.541 1.00 77.55  ? 233 ILE R CA  1 
ATOM 7541 C C   . ILE E 5 286 ? 98.801  112.490 117.825 1.00 80.23  ? 233 ILE R C   1 
ATOM 7542 O O   . ILE E 5 286 ? 99.224  112.838 118.933 1.00 79.21  ? 233 ILE R O   1 
ATOM 7543 C CB  . ILE E 5 286 ? 99.584  110.339 116.739 1.00 71.89  ? 233 ILE R CB  1 
ATOM 7544 C CG1 . ILE E 5 286 ? 99.383  108.827 116.771 1.00 78.57  ? 233 ILE R CG1 1 
ATOM 7545 C CG2 . ILE E 5 286 ? 100.949 110.708 117.292 1.00 69.55  ? 233 ILE R CG2 1 
ATOM 7546 C CD1 . ILE E 5 286 ? 100.549 108.053 116.237 1.00 80.65  ? 233 ILE R CD1 1 
ATOM 7547 N N   . CYS E 5 287 ? 98.610  113.366 116.837 1.00 82.87  ? 234 CYS R N   1 
ATOM 7548 C CA  . CYS E 5 287 ? 98.850  114.786 117.068 1.00 79.63  ? 234 CYS R CA  1 
ATOM 7549 C C   . CYS E 5 287 ? 97.906  115.348 118.122 1.00 77.66  ? 234 CYS R C   1 
ATOM 7550 O O   . CYS E 5 287 ? 98.251  116.311 118.814 1.00 80.61  ? 234 CYS R O   1 
ATOM 7551 C CB  . CYS E 5 287 ? 98.717  115.564 115.760 1.00 78.99  ? 234 CYS R CB  1 
ATOM 7552 S SG  . CYS E 5 287 ? 99.973  115.156 114.526 1.00 85.91  ? 234 CYS R SG  1 
ATOM 7553 N N   . LEU E 5 288 ? 96.714  114.763 118.261 1.00 74.66  ? 235 LEU R N   1 
ATOM 7554 C CA  . LEU E 5 288 ? 95.811  115.183 119.325 1.00 76.66  ? 235 LEU R CA  1 
ATOM 7555 C C   . LEU E 5 288 ? 96.266  114.666 120.685 1.00 76.51  ? 235 LEU R C   1 
ATOM 7556 O O   . LEU E 5 288 ? 96.025  115.320 121.706 1.00 76.34  ? 235 LEU R O   1 
ATOM 7557 C CB  . LEU E 5 288 ? 94.390  114.711 119.020 1.00 78.61  ? 235 LEU R CB  1 
ATOM 7558 C CG  . LEU E 5 288 ? 93.282  115.214 119.943 1.00 79.31  ? 235 LEU R CG  1 
ATOM 7559 C CD1 . LEU E 5 288 ? 93.217  116.730 119.916 1.00 78.46  ? 235 LEU R CD1 1 
ATOM 7560 C CD2 . LEU E 5 288 ? 91.948  114.611 119.544 1.00 78.51  ? 235 LEU R CD2 1 
ATOM 7561 N N   . LEU E 5 289 ? 96.912  113.498 120.722 1.00 79.55  ? 236 LEU R N   1 
ATOM 7562 C CA  . LEU E 5 289 ? 97.441  112.982 121.982 1.00 75.98  ? 236 LEU R CA  1 
ATOM 7563 C C   . LEU E 5 289 ? 98.551  113.872 122.522 1.00 78.61  ? 236 LEU R C   1 
ATOM 7564 O O   . LEU E 5 289 ? 98.643  114.092 123.735 1.00 81.96  ? 236 LEU R O   1 
ATOM 7565 C CB  . LEU E 5 289 ? 97.945  111.551 121.800 1.00 74.50  ? 236 LEU R CB  1 
ATOM 7566 C CG  . LEU E 5 289 ? 96.895  110.480 121.510 1.00 73.08  ? 236 LEU R CG  1 
ATOM 7567 C CD1 . LEU E 5 289 ? 97.562  109.150 121.229 1.00 73.72  ? 236 LEU R CD1 1 
ATOM 7568 C CD2 . LEU E 5 289 ? 95.936  110.359 122.678 1.00 70.90  ? 236 LEU R CD2 1 
ATOM 7569 N N   . TRP E 5 290 ? 99.412  114.382 121.639 1.00 80.78  ? 237 TRP R N   1 
ATOM 7570 C CA  . TRP E 5 290 ? 100.454 115.307 122.069 1.00 81.06  ? 237 TRP R CA  1 
ATOM 7571 C C   . TRP E 5 290 ? 99.857  116.590 122.629 1.00 81.29  ? 237 TRP R C   1 
ATOM 7572 O O   . TRP E 5 290 ? 100.362 117.140 123.615 1.00 82.63  ? 237 TRP R O   1 
ATOM 7573 C CB  . TRP E 5 290 ? 101.392 115.619 120.907 1.00 78.36  ? 237 TRP R CB  1 
ATOM 7574 C CG  . TRP E 5 290 ? 102.316 114.504 120.570 1.00 78.18  ? 237 TRP R CG  1 
ATOM 7575 C CD1 . TRP E 5 290 ? 102.064 113.453 119.742 1.00 77.46  ? 237 TRP R CD1 1 
ATOM 7576 C CD2 . TRP E 5 290 ? 103.654 114.331 121.044 1.00 79.58  ? 237 TRP R CD2 1 
ATOM 7577 N NE1 . TRP E 5 290 ? 103.161 112.632 119.673 1.00 74.43  ? 237 TRP R NE1 1 
ATOM 7578 C CE2 . TRP E 5 290 ? 104.152 113.150 120.464 1.00 76.87  ? 237 TRP R CE2 1 
ATOM 7579 C CE3 . TRP E 5 290 ? 104.479 115.059 121.905 1.00 78.73  ? 237 TRP R CE3 1 
ATOM 7580 C CZ2 . TRP E 5 290 ? 105.436 112.681 120.714 1.00 76.35  ? 237 TRP R CZ2 1 
ATOM 7581 C CZ3 . TRP E 5 290 ? 105.754 114.590 122.154 1.00 77.74  ? 237 TRP R CZ3 1 
ATOM 7582 C CH2 . TRP E 5 290 ? 106.219 113.412 121.562 1.00 79.80  ? 237 TRP R CH2 1 
ATOM 7583 N N   . ALA E 5 291 ? 98.787  117.089 122.006 1.00 85.51  ? 238 ALA R N   1 
ATOM 7584 C CA  . ALA E 5 291 ? 98.129  118.287 122.515 1.00 85.33  ? 238 ALA R CA  1 
ATOM 7585 C C   . ALA E 5 291 ? 97.566  118.054 123.910 1.00 87.33  ? 238 ALA R C   1 
ATOM 7586 O O   . ALA E 5 291 ? 97.700  118.911 124.791 1.00 90.83  ? 238 ALA R O   1 
ATOM 7587 C CB  . ALA E 5 291 ? 97.026  118.729 121.556 1.00 82.17  ? 238 ALA R CB  1 
ATOM 7588 N N   . LEU E 5 292 ? 96.934  116.900 124.132 1.00 85.59  ? 239 LEU R N   1 
ATOM 7589 C CA  . LEU E 5 292 ? 96.445  116.580 125.469 1.00 85.05  ? 239 LEU R CA  1 
ATOM 7590 C C   . LEU E 5 292 ? 97.592  116.335 126.438 1.00 86.99  ? 239 LEU R C   1 
ATOM 7591 O O   . LEU E 5 292 ? 97.460  116.612 127.634 1.00 88.30  ? 239 LEU R O   1 
ATOM 7592 C CB  . LEU E 5 292 ? 95.524  115.363 125.421 1.00 86.48  ? 239 LEU R CB  1 
ATOM 7593 C CG  . LEU E 5 292 ? 94.206  115.531 124.664 1.00 89.94  ? 239 LEU R CG  1 
ATOM 7594 C CD1 . LEU E 5 292 ? 93.391  114.250 124.723 1.00 86.96  ? 239 LEU R CD1 1 
ATOM 7595 C CD2 . LEU E 5 292 ? 93.412  116.702 125.219 1.00 89.66  ? 239 LEU R CD2 1 
ATOM 7596 N N   . SER E 5 293 ? 98.716  115.811 125.945 1.00 90.41  ? 240 SER R N   1 
ATOM 7597 C CA  . SER E 5 293 ? 99.875  115.602 126.806 1.00 92.75  ? 240 SER R CA  1 
ATOM 7598 C C   . SER E 5 293 ? 100.426 116.924 127.324 1.00 95.27  ? 240 SER R C   1 
ATOM 7599 O O   . SER E 5 293 ? 100.782 117.037 128.502 1.00 96.39  ? 240 SER R O   1 
ATOM 7600 C CB  . SER E 5 293 ? 100.954 114.831 126.050 1.00 91.81  ? 240 SER R CB  1 
ATOM 7601 O OG  . SER E 5 293 ? 102.100 114.634 126.858 1.00 95.00  ? 240 SER R OG  1 
ATOM 7602 N N   . PHE E 5 294 ? 100.513 117.935 126.455 1.00 97.98  ? 241 PHE R N   1 
ATOM 7603 C CA  . PHE E 5 294 ? 100.956 119.253 126.898 1.00 96.83  ? 241 PHE R CA  1 
ATOM 7604 C C   . PHE E 5 294 ? 99.979  119.855 127.900 1.00 96.91  ? 241 PHE R C   1 
ATOM 7605 O O   . PHE E 5 294 ? 100.393 120.475 128.886 1.00 98.05  ? 241 PHE R O   1 
ATOM 7606 C CB  . PHE E 5 294 ? 101.125 120.182 125.696 1.00 95.58  ? 241 PHE R CB  1 
ATOM 7607 C CG  . PHE E 5 294 ? 102.388 119.949 124.920 1.00 99.15  ? 241 PHE R CG  1 
ATOM 7608 C CD1 . PHE E 5 294 ? 103.573 119.654 125.572 1.00 99.39  ? 241 PHE R CD1 1 
ATOM 7609 C CD2 . PHE E 5 294 ? 102.392 120.027 123.537 1.00 99.48  ? 241 PHE R CD2 1 
ATOM 7610 C CE1 . PHE E 5 294 ? 104.738 119.443 124.859 1.00 99.02  ? 241 PHE R CE1 1 
ATOM 7611 C CE2 . PHE E 5 294 ? 103.553 119.815 122.819 1.00 98.92  ? 241 PHE R CE2 1 
ATOM 7612 C CZ  . PHE E 5 294 ? 104.728 119.522 123.481 1.00 99.99  ? 241 PHE R CZ  1 
ATOM 7613 N N   . ILE E 5 295 ? 98.678  119.691 127.659 1.00 97.19  ? 242 ILE R N   1 
ATOM 7614 C CA  . ILE E 5 295 ? 97.676  120.212 128.582 1.00 97.43  ? 242 ILE R CA  1 
ATOM 7615 C C   . ILE E 5 295 ? 97.738  119.478 129.915 1.00 99.52  ? 242 ILE R C   1 
ATOM 7616 O O   . ILE E 5 295 ? 97.636  120.092 130.984 1.00 101.05 ? 242 ILE R O   1 
ATOM 7617 C CB  . ILE E 5 295 ? 96.277  120.124 127.950 1.00 96.92  ? 242 ILE R CB  1 
ATOM 7618 C CG1 . ILE E 5 295 ? 96.206  120.999 126.699 1.00 96.18  ? 242 ILE R CG1 1 
ATOM 7619 C CG2 . ILE E 5 295 ? 95.210  120.539 128.949 1.00 97.17  ? 242 ILE R CG2 1 
ATOM 7620 C CD1 . ILE E 5 295 ? 94.865  120.959 126.005 1.00 97.08  ? 242 ILE R CD1 1 
ATOM 7621 N N   . SER E 5 296 ? 97.906  118.155 129.877 1.00 103.58 ? 243 SER R N   1 
ATOM 7622 C CA  . SER E 5 296 ? 97.933  117.364 131.102 1.00 102.90 ? 243 SER R CA  1 
ATOM 7623 C C   . SER E 5 296 ? 99.157  117.645 131.962 1.00 102.87 ? 243 SER R C   1 
ATOM 7624 O O   . SER E 5 296 ? 99.130  117.353 133.161 1.00 103.89 ? 243 SER R O   1 
ATOM 7625 C CB  . SER E 5 296 ? 97.862  115.874 130.767 1.00 100.92 ? 243 SER R CB  1 
ATOM 7626 O OG  . SER E 5 296 ? 98.962  115.477 129.970 1.00 100.27 ? 243 SER R OG  1 
ATOM 7627 N N   . ILE E 5 297 ? 100.223 118.198 131.391 1.00 108.13 ? 244 ILE R N   1 
ATOM 7628 C CA  . ILE E 5 297 ? 101.419 118.535 132.153 1.00 108.68 ? 244 ILE R CA  1 
ATOM 7629 C C   . ILE E 5 297 ? 101.480 120.030 132.470 1.00 111.61 ? 244 ILE R C   1 
ATOM 7630 O O   . ILE E 5 297 ? 102.544 120.545 132.809 1.00 113.50 ? 244 ILE R O   1 
ATOM 7631 C CB  . ILE E 5 297 ? 102.697 118.074 131.437 1.00 108.63 ? 244 ILE R CB  1 
ATOM 7632 C CG1 . ILE E 5 297 ? 102.879 118.847 130.131 1.00 109.51 ? 244 ILE R CG1 1 
ATOM 7633 C CG2 . ILE E 5 297 ? 102.651 116.579 131.181 1.00 106.63 ? 244 ILE R CG2 1 
ATOM 7634 C CD1 . ILE E 5 297 ? 104.254 118.714 129.528 1.00 108.54 ? 244 ILE R CD1 1 
ATOM 7635 N N   . THR E 5 298 ? 100.356 120.738 132.353 1.00 125.85 ? 245 THR R N   1 
ATOM 7636 C CA  . THR E 5 298 ? 100.350 122.165 132.668 1.00 126.08 ? 245 THR R CA  1 
ATOM 7637 C C   . THR E 5 298 ? 100.759 122.451 134.109 1.00 127.67 ? 245 THR R C   1 
ATOM 7638 O O   . THR E 5 298 ? 101.598 123.344 134.319 1.00 127.23 ? 245 THR R O   1 
ATOM 7639 C CB  . THR E 5 298 ? 98.976  122.762 132.344 1.00 126.31 ? 245 THR R CB  1 
ATOM 7640 O OG1 . THR E 5 298 ? 98.667  122.534 130.963 1.00 126.99 ? 245 THR R OG1 1 
ATOM 7641 C CG2 . THR E 5 298 ? 98.966  124.257 132.617 1.00 126.59 ? 245 THR R CG2 1 
ATOM 7642 N N   . PRO E 5 299 ? 100.240 121.760 135.131 1.00 132.03 ? 246 PRO R N   1 
ATOM 7643 C CA  . PRO E 5 299 ? 100.739 122.009 136.493 1.00 131.35 ? 246 PRO R CA  1 
ATOM 7644 C C   . PRO E 5 299 ? 102.203 121.655 136.680 1.00 130.69 ? 246 PRO R C   1 
ATOM 7645 O O   . PRO E 5 299 ? 102.824 122.146 137.630 1.00 133.48 ? 246 PRO R O   1 
ATOM 7646 C CB  . PRO E 5 299 ? 99.837  121.128 137.370 1.00 130.27 ? 246 PRO R CB  1 
ATOM 7647 C CG  . PRO E 5 299 ? 98.622  120.897 136.554 1.00 130.63 ? 246 PRO R CG  1 
ATOM 7648 C CD  . PRO E 5 299 ? 99.110  120.812 135.147 1.00 130.33 ? 246 PRO R CD  1 
ATOM 7649 N N   . VAL E 5 300 ? 102.772 120.813 135.816 1.00 133.00 ? 247 VAL R N   1 
ATOM 7650 C CA  . VAL E 5 300 ? 104.158 120.391 135.993 1.00 134.88 ? 247 VAL R CA  1 
ATOM 7651 C C   . VAL E 5 300 ? 105.111 121.562 135.783 1.00 135.86 ? 247 VAL R C   1 
ATOM 7652 O O   . VAL E 5 300 ? 106.006 121.806 136.600 1.00 136.56 ? 247 VAL R O   1 
ATOM 7653 C CB  . VAL E 5 300 ? 104.489 119.222 135.048 1.00 135.09 ? 247 VAL R CB  1 
ATOM 7654 C CG1 . VAL E 5 300 ? 105.947 118.822 135.198 1.00 134.42 ? 247 VAL R CG1 1 
ATOM 7655 C CG2 . VAL E 5 300 ? 103.574 118.040 135.328 1.00 134.72 ? 247 VAL R CG2 1 
ATOM 7656 N N   . TRP E 5 301 ? 104.935 122.307 134.692 1.00 138.22 ? 248 TRP R N   1 
ATOM 7657 C CA  . TRP E 5 301 ? 105.854 123.394 134.383 1.00 138.97 ? 248 TRP R CA  1 
ATOM 7658 C C   . TRP E 5 301 ? 105.484 124.703 135.063 1.00 138.02 ? 248 TRP R C   1 
ATOM 7659 O O   . TRP E 5 301 ? 106.321 125.611 135.122 1.00 138.30 ? 248 TRP R O   1 
ATOM 7660 C CB  . TRP E 5 301 ? 105.937 123.608 132.867 1.00 137.13 ? 248 TRP R CB  1 
ATOM 7661 C CG  . TRP E 5 301 ? 104.710 124.205 132.259 1.00 137.27 ? 248 TRP R CG  1 
ATOM 7662 C CD1 . TRP E 5 301 ? 103.557 123.556 131.935 1.00 137.60 ? 248 TRP R CD1 1 
ATOM 7663 C CD2 . TRP E 5 301 ? 104.521 125.573 131.878 1.00 139.90 ? 248 TRP R CD2 1 
ATOM 7664 N NE1 . TRP E 5 301 ? 102.655 124.435 131.386 1.00 137.35 ? 248 TRP R NE1 1 
ATOM 7665 C CE2 . TRP E 5 301 ? 103.224 125.681 131.339 1.00 140.28 ? 248 TRP R CE2 1 
ATOM 7666 C CE3 . TRP E 5 301 ? 105.321 126.718 131.945 1.00 138.57 ? 248 TRP R CE3 1 
ATOM 7667 C CZ2 . TRP E 5 301 ? 102.708 126.888 130.870 1.00 139.38 ? 248 TRP R CZ2 1 
ATOM 7668 C CZ3 . TRP E 5 301 ? 104.807 127.915 131.479 1.00 137.06 ? 248 TRP R CZ3 1 
ATOM 7669 C CH2 . TRP E 5 301 ? 103.514 127.990 130.948 1.00 138.66 ? 248 TRP R CH2 1 
ATOM 7670 N N   . LEU E 5 302 ? 104.259 124.827 135.576 1.00 143.63 ? 249 LEU R N   1 
ATOM 7671 C CA  . LEU E 5 302 ? 103.881 126.016 136.328 1.00 145.19 ? 249 LEU R CA  1 
ATOM 7672 C C   . LEU E 5 302 ? 104.446 126.017 137.741 1.00 145.50 ? 249 LEU R C   1 
ATOM 7673 O O   . LEU E 5 302 ? 104.606 127.092 138.328 1.00 145.62 ? 249 LEU R O   1 
ATOM 7674 C CB  . LEU E 5 302 ? 102.358 126.147 136.390 1.00 144.69 ? 249 LEU R CB  1 
ATOM 7675 C CG  . LEU E 5 302 ? 101.637 126.478 135.084 1.00 144.30 ? 249 LEU R CG  1 
ATOM 7676 C CD1 . LEU E 5 302 ? 100.144 126.621 135.324 1.00 143.48 ? 249 LEU R CD1 1 
ATOM 7677 C CD2 . LEU E 5 302 ? 102.207 127.738 134.456 1.00 143.61 ? 249 LEU R CD2 1 
ATOM 7678 N N   . TYR E 5 303 ? 104.745 124.842 138.300 1.00 152.24 ? 250 TYR R N   1 
ATOM 7679 C CA  . TYR E 5 303 ? 105.249 124.728 139.664 1.00 153.37 ? 250 TYR R CA  1 
ATOM 7680 C C   . TYR E 5 303 ? 106.651 124.131 139.716 1.00 154.03 ? 250 TYR R C   1 
ATOM 7681 O O   . TYR E 5 303 ? 107.097 123.703 140.785 1.00 153.94 ? 250 TYR R O   1 
ATOM 7682 C CB  . TYR E 5 303 ? 104.288 123.898 140.517 1.00 152.60 ? 250 TYR R CB  1 
ATOM 7683 C CG  . TYR E 5 303 ? 102.891 124.469 140.593 1.00 153.26 ? 250 TYR R CG  1 
ATOM 7684 C CD1 . TYR E 5 303 ? 102.678 125.841 140.573 1.00 153.29 ? 250 TYR R CD1 1 
ATOM 7685 C CD2 . TYR E 5 303 ? 101.784 123.637 140.685 1.00 154.18 ? 250 TYR R CD2 1 
ATOM 7686 C CE1 . TYR E 5 303 ? 101.403 126.367 140.640 1.00 153.50 ? 250 TYR R CE1 1 
ATOM 7687 C CE2 . TYR E 5 303 ? 100.506 124.154 140.754 1.00 154.52 ? 250 TYR R CE2 1 
ATOM 7688 C CZ  . TYR E 5 303 ? 100.321 125.519 140.731 1.00 154.01 ? 250 TYR R CZ  1 
ATOM 7689 O OH  . TYR E 5 303 ? 99.049  126.040 140.799 1.00 153.60 ? 250 TYR R OH  1 
ATOM 7690 N N   . ALA E 5 304 ? 107.356 124.090 138.586 1.00 157.81 ? 251 ALA R N   1 
ATOM 7691 C CA  . ALA E 5 304 ? 108.708 123.535 138.535 1.00 157.64 ? 251 ALA R CA  1 
ATOM 7692 C C   . ALA E 5 304 ? 109.699 124.647 138.850 1.00 158.20 ? 251 ALA R C   1 
ATOM 7693 O O   . ALA E 5 304 ? 110.205 125.332 137.959 1.00 158.64 ? 251 ALA R O   1 
ATOM 7694 C CB  . ALA E 5 304 ? 108.983 122.905 137.176 1.00 157.15 ? 251 ALA R CB  1 
ATOM 7695 N N   . ARG E 5 305 ? 109.984 124.825 140.137 1.00 157.40 ? 252 ARG R N   1 
ATOM 7696 C CA  . ARG E 5 305 ? 110.909 125.844 140.607 1.00 156.99 ? 252 ARG R CA  1 
ATOM 7697 C C   . ARG E 5 305 ? 111.970 125.194 141.485 1.00 157.71 ? 252 ARG R C   1 
ATOM 7698 O O   . ARG E 5 305 ? 111.766 124.113 142.043 1.00 158.11 ? 252 ARG R O   1 
ATOM 7699 C CB  . ARG E 5 305 ? 110.186 126.952 141.387 1.00 156.41 ? 252 ARG R CB  1 
ATOM 7700 C CG  . ARG E 5 305 ? 108.980 127.533 140.668 1.00 155.95 ? 252 ARG R CG  1 
ATOM 7701 C CD  . ARG E 5 305 ? 109.366 128.117 139.320 1.00 156.12 ? 252 ARG R CD  1 
ATOM 7702 N NE  . ARG E 5 305 ? 108.199 128.535 138.553 1.00 156.29 ? 252 ARG R NE  1 
ATOM 7703 C CZ  . ARG E 5 305 ? 108.248 129.018 137.319 1.00 156.61 ? 252 ARG R CZ  1 
ATOM 7704 N NH1 . ARG E 5 305 ? 109.396 129.161 136.677 1.00 156.64 ? 252 ARG R NH1 1 
ATOM 7705 N NH2 . ARG E 5 305 ? 107.116 129.367 136.713 1.00 156.35 ? 252 ARG R NH2 1 
ATOM 7706 N N   . LEU E 5 306 ? 113.112 125.867 141.596 1.00 167.83 ? 253 LEU R N   1 
ATOM 7707 C CA  . LEU E 5 306 ? 114.206 125.350 142.406 1.00 168.11 ? 253 LEU R CA  1 
ATOM 7708 C C   . LEU E 5 306 ? 113.807 125.301 143.875 1.00 167.87 ? 253 LEU R C   1 
ATOM 7709 O O   . LEU E 5 306 ? 113.184 126.229 144.399 1.00 167.26 ? 253 LEU R O   1 
ATOM 7710 C CB  . LEU E 5 306 ? 115.454 126.213 142.231 1.00 167.17 ? 253 LEU R CB  1 
ATOM 7711 C CG  . LEU E 5 306 ? 116.067 126.252 140.831 1.00 167.13 ? 253 LEU R CG  1 
ATOM 7712 C CD1 . LEU E 5 306 ? 117.319 127.113 140.825 1.00 166.83 ? 253 LEU R CD1 1 
ATOM 7713 C CD2 . LEU E 5 306 ? 116.377 124.847 140.344 1.00 167.42 ? 253 LEU R CD2 1 
ATOM 7714 N N   . ILE E 5 307 ? 114.170 124.210 144.540 1.00 170.30 ? 254 ILE R N   1 
ATOM 7715 C CA  . ILE E 5 307 ? 113.873 123.998 145.951 1.00 170.57 ? 254 ILE R CA  1 
ATOM 7716 C C   . ILE E 5 307 ? 115.177 124.158 146.730 1.00 170.77 ? 254 ILE R C   1 
ATOM 7717 O O   . ILE E 5 307 ? 116.089 123.331 146.584 1.00 170.47 ? 254 ILE R O   1 
ATOM 7718 C CB  . ILE E 5 307 ? 113.243 122.622 146.200 1.00 170.86 ? 254 ILE R CB  1 
ATOM 7719 C CG1 . ILE E 5 307 ? 111.921 122.495 145.442 1.00 170.78 ? 254 ILE R CG1 1 
ATOM 7720 C CG2 . ILE E 5 307 ? 113.032 122.396 147.689 1.00 169.44 ? 254 ILE R CG2 1 
ATOM 7721 C CD1 . ILE E 5 307 ? 111.237 121.160 145.634 1.00 170.30 ? 254 ILE R CD1 1 
ATOM 7722 N N   . PRO E 5 308 ? 115.317 125.194 147.557 1.00 170.07 ? 255 PRO R N   1 
ATOM 7723 C CA  . PRO E 5 308 ? 116.562 125.365 148.316 1.00 170.15 ? 255 PRO R CA  1 
ATOM 7724 C C   . PRO E 5 308 ? 116.692 124.350 149.440 1.00 170.43 ? 255 PRO R C   1 
ATOM 7725 O O   . PRO E 5 308 ? 116.016 124.454 150.468 1.00 169.65 ? 255 PRO R O   1 
ATOM 7726 C CB  . PRO E 5 308 ? 116.449 126.796 148.855 1.00 168.85 ? 255 PRO R CB  1 
ATOM 7727 C CG  . PRO E 5 308 ? 114.980 127.050 148.930 1.00 168.80 ? 255 PRO R CG  1 
ATOM 7728 C CD  . PRO E 5 308 ? 114.370 126.301 147.779 1.00 168.98 ? 255 PRO R CD  1 
ATOM 7729 N N   . PHE E 5 309 ? 117.560 123.363 149.250 1.00 167.50 ? 256 PHE R N   1 
ATOM 7730 C CA  . PHE E 5 309 ? 117.821 122.370 150.276 1.00 166.69 ? 256 PHE R CA  1 
ATOM 7731 C C   . PHE E 5 309 ? 118.696 122.960 151.377 1.00 166.76 ? 256 PHE R C   1 
ATOM 7732 O O   . PHE E 5 309 ? 119.383 123.963 151.166 1.00 165.86 ? 256 PHE R O   1 
ATOM 7733 C CB  . PHE E 5 309 ? 118.495 121.147 149.660 1.00 166.22 ? 256 PHE R CB  1 
ATOM 7734 C CG  . PHE E 5 309 ? 117.594 120.346 148.766 1.00 166.91 ? 256 PHE R CG  1 
ATOM 7735 C CD1 . PHE E 5 309 ? 116.788 119.347 149.288 1.00 166.31 ? 256 PHE R CD1 1 
ATOM 7736 C CD2 . PHE E 5 309 ? 117.551 120.591 147.404 1.00 166.70 ? 256 PHE R CD2 1 
ATOM 7737 C CE1 . PHE E 5 309 ? 115.957 118.608 148.469 1.00 165.93 ? 256 PHE R CE1 1 
ATOM 7738 C CE2 . PHE E 5 309 ? 116.721 119.855 146.579 1.00 165.92 ? 256 PHE R CE2 1 
ATOM 7739 C CZ  . PHE E 5 309 ? 115.924 118.862 147.112 1.00 165.53 ? 256 PHE R CZ  1 
ATOM 7740 N N   . PRO E 5 310 ? 118.673 122.367 152.572 1.00 167.83 ? 257 PRO R N   1 
ATOM 7741 C CA  . PRO E 5 310 ? 119.551 122.849 153.645 1.00 167.15 ? 257 PRO R CA  1 
ATOM 7742 C C   . PRO E 5 310 ? 121.014 122.792 153.230 1.00 166.49 ? 257 PRO R C   1 
ATOM 7743 O O   . PRO E 5 310 ? 121.456 121.854 152.564 1.00 165.80 ? 257 PRO R O   1 
ATOM 7744 C CB  . PRO E 5 310 ? 119.254 121.890 154.803 1.00 165.84 ? 257 PRO R CB  1 
ATOM 7745 C CG  . PRO E 5 310 ? 117.866 121.417 154.543 1.00 165.74 ? 257 PRO R CG  1 
ATOM 7746 C CD  . PRO E 5 310 ? 117.741 121.329 153.048 1.00 166.07 ? 257 PRO R CD  1 
ATOM 7747 N N   . GLY E 5 311 ? 121.763 123.810 153.632 1.00 166.10 ? 258 GLY R N   1 
ATOM 7748 C CA  . GLY E 5 311 ? 123.143 123.939 153.217 1.00 165.96 ? 258 GLY R CA  1 
ATOM 7749 C C   . GLY E 5 311 ? 123.280 124.747 151.941 1.00 166.28 ? 258 GLY R C   1 
ATOM 7750 O O   . GLY E 5 311 ? 122.378 125.480 151.523 1.00 166.49 ? 258 GLY R O   1 
ATOM 7751 N N   . GLY E 5 312 ? 124.441 124.603 151.312 1.00 156.25 ? 259 GLY R N   1 
ATOM 7752 C CA  . GLY E 5 312 ? 124.750 125.298 150.082 1.00 155.56 ? 259 GLY R CA  1 
ATOM 7753 C C   . GLY E 5 312 ? 124.350 124.581 148.812 1.00 156.85 ? 259 GLY R C   1 
ATOM 7754 O O   . GLY E 5 312 ? 124.687 125.051 147.720 1.00 156.10 ? 259 GLY R O   1 
ATOM 7755 N N   . ALA E 5 313 ? 123.642 123.460 148.914 1.00 162.16 ? 260 ALA R N   1 
ATOM 7756 C CA  . ALA E 5 313 ? 123.250 122.674 147.754 1.00 161.53 ? 260 ALA R CA  1 
ATOM 7757 C C   . ALA E 5 313 ? 121.772 122.877 147.448 1.00 161.67 ? 260 ALA R C   1 
ATOM 7758 O O   . ALA E 5 313 ? 120.942 122.956 148.359 1.00 160.64 ? 260 ALA R O   1 
ATOM 7759 C CB  . ALA E 5 313 ? 123.535 121.188 147.980 1.00 159.97 ? 260 ALA R CB  1 
ATOM 7760 N N   . VAL E 5 314 ? 121.450 122.963 146.157 1.00 168.96 ? 261 VAL R N   1 
ATOM 7761 C CA  . VAL E 5 314 ? 120.079 123.101 145.688 1.00 169.01 ? 261 VAL R CA  1 
ATOM 7762 C C   . VAL E 5 314 ? 119.826 122.053 144.613 1.00 168.81 ? 261 VAL R C   1 
ATOM 7763 O O   . VAL E 5 314 ? 120.753 121.526 143.993 1.00 167.96 ? 261 VAL R O   1 
ATOM 7764 C CB  . VAL E 5 314 ? 119.781 124.515 145.144 1.00 168.16 ? 261 VAL R CB  1 
ATOM 7765 C CG1 . VAL E 5 314 ? 119.905 125.549 146.252 1.00 166.65 ? 261 VAL R CG1 1 
ATOM 7766 C CG2 . VAL E 5 314 ? 120.714 124.847 143.990 1.00 166.56 ? 261 VAL R CG2 1 
ATOM 7767 N N   . GLY E 5 315 ? 118.553 121.754 144.399 1.00 177.15 ? 262 GLY R N   1 
ATOM 7768 C CA  . GLY E 5 315 ? 118.167 120.746 143.430 1.00 176.46 ? 262 GLY R CA  1 
ATOM 7769 C C   . GLY E 5 315 ? 116.877 121.120 142.735 1.00 176.51 ? 262 GLY R C   1 
ATOM 7770 O O   . GLY E 5 315 ? 116.041 121.849 143.274 1.00 175.84 ? 262 GLY R O   1 
ATOM 7771 N N   . CYS E 5 316 ? 116.725 120.608 141.516 1.00 168.85 ? 263 CYS R N   1 
ATOM 7772 C CA  . CYS E 5 316 ? 115.529 120.860 140.725 1.00 169.02 ? 263 CYS R CA  1 
ATOM 7773 C C   . CYS E 5 316 ? 114.375 119.994 141.213 1.00 168.57 ? 263 CYS R C   1 
ATOM 7774 O O   . CYS E 5 316 ? 114.541 118.800 141.477 1.00 168.27 ? 263 CYS R O   1 
ATOM 7775 C CB  . CYS E 5 316 ? 115.804 120.586 139.247 1.00 168.83 ? 263 CYS R CB  1 
ATOM 7776 S SG  . CYS E 5 316 ? 114.391 120.832 138.146 1.00 169.74 ? 263 CYS R SG  1 
ATOM 7777 N N   . GLY E 5 317 ? 113.203 120.604 141.329 1.00 171.41 ? 264 GLY R N   1 
ATOM 7778 C CA  . GLY E 5 317 ? 112.041 119.880 141.797 1.00 170.98 ? 264 GLY R CA  1 
ATOM 7779 C C   . GLY E 5 317 ? 110.777 120.678 141.575 1.00 171.77 ? 264 GLY R C   1 
ATOM 7780 O O   . GLY E 5 317 ? 110.766 121.678 140.855 1.00 172.02 ? 264 GLY R O   1 
ATOM 7781 N N   . ILE E 5 318 ? 109.702 120.215 142.208 1.00 164.79 ? 265 ILE R N   1 
ATOM 7782 C CA  . ILE E 5 318 ? 108.394 120.854 142.125 1.00 164.84 ? 265 ILE R CA  1 
ATOM 7783 C C   . ILE E 5 318 ? 108.143 121.581 143.438 1.00 164.69 ? 265 ILE R C   1 
ATOM 7784 O O   . ILE E 5 318 ? 108.164 120.966 144.511 1.00 164.08 ? 265 ILE R O   1 
ATOM 7785 C CB  . ILE E 5 318 ? 107.281 119.836 141.837 1.00 163.60 ? 265 ILE R CB  1 
ATOM 7786 C CG1 . ILE E 5 318 ? 107.580 119.072 140.547 1.00 163.74 ? 265 ILE R CG1 1 
ATOM 7787 C CG2 . ILE E 5 318 ? 105.936 120.536 141.741 1.00 162.83 ? 265 ILE R CG2 1 
ATOM 7788 C CD1 . ILE E 5 318 ? 107.677 119.956 139.325 1.00 163.64 ? 265 ILE R CD1 1 
ATOM 7789 N N   . ARG E 5 319 ? 107.901 122.885 143.353 1.00 163.25 ? 266 ARG R N   1 
ATOM 7790 C CA  . ARG E 5 319 ? 107.672 123.733 144.520 1.00 162.78 ? 266 ARG R CA  1 
ATOM 7791 C C   . ARG E 5 319 ? 106.223 124.209 144.472 1.00 163.57 ? 266 ARG R C   1 
ATOM 7792 O O   . ARG E 5 319 ? 105.914 125.253 143.895 1.00 162.90 ? 266 ARG R O   1 
ATOM 7793 C CB  . ARG E 5 319 ? 108.648 124.906 144.545 1.00 161.53 ? 266 ARG R CB  1 
ATOM 7794 C CG  . ARG E 5 319 ? 109.006 125.387 145.941 1.00 161.23 ? 266 ARG R CG  1 
ATOM 7795 C CD  . ARG E 5 319 ? 110.036 126.503 145.892 1.00 161.94 ? 266 ARG R CD  1 
ATOM 7796 N NE  . ARG E 5 319 ? 110.657 126.731 147.191 1.00 163.18 ? 266 ARG R NE  1 
ATOM 7797 C CZ  . ARG E 5 319 ? 110.170 127.538 148.123 1.00 162.58 ? 266 ARG R CZ  1 
ATOM 7798 N NH1 . ARG E 5 319 ? 109.048 128.214 147.934 1.00 162.27 ? 266 ARG R NH1 1 
ATOM 7799 N NH2 . ARG E 5 319 ? 110.823 127.671 149.273 1.00 161.31 ? 266 ARG R NH2 1 
ATOM 7800 N N   . LEU E 5 320 ? 105.335 123.430 145.082 1.00 169.41 ? 267 LEU R N   1 
ATOM 7801 C CA  . LEU E 5 320 ? 103.922 123.774 145.075 1.00 169.27 ? 267 LEU R CA  1 
ATOM 7802 C C   . LEU E 5 320 ? 103.685 125.028 145.913 1.00 169.46 ? 267 LEU R C   1 
ATOM 7803 O O   . LEU E 5 320 ? 104.354 125.230 146.932 1.00 169.12 ? 267 LEU R O   1 
ATOM 7804 C CB  . LEU E 5 320 ? 103.089 122.614 145.618 1.00 169.25 ? 267 LEU R CB  1 
ATOM 7805 C CG  . LEU E 5 320 ? 103.210 121.289 144.861 1.00 168.77 ? 267 LEU R CG  1 
ATOM 7806 C CD1 . LEU E 5 320 ? 102.442 120.188 145.573 1.00 168.21 ? 267 LEU R CD1 1 
ATOM 7807 C CD2 . LEU E 5 320 ? 102.722 121.446 143.430 1.00 168.17 ? 267 LEU R CD2 1 
ATOM 7808 N N   . PRO E 5 321 ? 102.751 125.893 145.508 1.00 172.11 ? 268 PRO R N   1 
ATOM 7809 C CA  . PRO E 5 321 ? 102.466 127.088 146.318 1.00 172.12 ? 268 PRO R CA  1 
ATOM 7810 C C   . PRO E 5 321 ? 101.975 126.767 147.718 1.00 172.82 ? 268 PRO R C   1 
ATOM 7811 O O   . PRO E 5 321 ? 102.291 127.504 148.661 1.00 171.22 ? 268 PRO R O   1 
ATOM 7812 C CB  . PRO E 5 321 ? 101.397 127.821 145.495 1.00 171.40 ? 268 PRO R CB  1 
ATOM 7813 C CG  . PRO E 5 321 ? 100.771 126.756 144.654 1.00 171.25 ? 268 PRO R CG  1 
ATOM 7814 C CD  . PRO E 5 321 ? 101.878 125.802 144.326 1.00 170.63 ? 268 PRO R CD  1 
ATOM 7815 N N   . ASN E 5 322 ? 101.212 125.689 147.884 1.00 174.98 ? 269 ASN R N   1 
ATOM 7816 C CA  . ASN E 5 322 ? 100.699 125.263 149.185 1.00 173.55 ? 269 ASN R CA  1 
ATOM 7817 C C   . ASN E 5 322 ? 101.007 123.782 149.359 1.00 172.92 ? 269 ASN R C   1 
ATOM 7818 O O   . ASN E 5 322 ? 100.119 122.931 149.221 1.00 171.92 ? 269 ASN R O   1 
ATOM 7819 C CB  . ASN E 5 322 ? 99.200  125.538 149.307 1.00 172.96 ? 269 ASN R CB  1 
ATOM 7820 C CG  . ASN E 5 322 ? 98.857  126.998 149.091 1.00 172.61 ? 269 ASN R CG  1 
ATOM 7821 O OD1 . ASN E 5 322 ? 98.850  127.791 150.032 1.00 172.41 ? 269 ASN R OD1 1 
ATOM 7822 N ND2 . ASN E 5 322 ? 98.572  127.361 147.846 1.00 172.04 ? 269 ASN R ND2 1 
ATOM 7823 N N   . PRO E 5 323 ? 102.259 123.438 149.673 1.00 170.61 ? 270 PRO R N   1 
ATOM 7824 C CA  . PRO E 5 323 ? 102.630 122.016 149.760 1.00 170.22 ? 270 PRO R CA  1 
ATOM 7825 C C   . PRO E 5 323 ? 101.859 121.245 150.817 1.00 170.28 ? 270 PRO R C   1 
ATOM 7826 O O   . PRO E 5 323 ? 101.737 120.020 150.701 1.00 169.06 ? 270 PRO R O   1 
ATOM 7827 C CB  . PRO E 5 323 ? 104.129 122.064 150.083 1.00 169.46 ? 270 PRO R CB  1 
ATOM 7828 C CG  . PRO E 5 323 ? 104.334 123.398 150.721 1.00 168.49 ? 270 PRO R CG  1 
ATOM 7829 C CD  . PRO E 5 323 ? 103.378 124.326 150.032 1.00 168.91 ? 270 PRO R CD  1 
ATOM 7830 N N   . ASP E 5 324 ? 101.339 121.920 151.844 1.00 172.98 ? 271 ASP R N   1 
ATOM 7831 C CA  . ASP E 5 324 ? 100.558 121.227 152.863 1.00 172.82 ? 271 ASP R CA  1 
ATOM 7832 C C   . ASP E 5 324 ? 99.273  120.650 152.282 1.00 173.00 ? 271 ASP R C   1 
ATOM 7833 O O   . ASP E 5 324 ? 98.870  119.535 152.633 1.00 171.52 ? 271 ASP R O   1 
ATOM 7834 C CB  . ASP E 5 324 ? 100.245 122.178 154.018 1.00 172.36 ? 271 ASP R CB  1 
ATOM 7835 C CG  . ASP E 5 324 ? 101.495 122.739 154.666 1.00 171.95 ? 271 ASP R CG  1 
ATOM 7836 O OD1 . ASP E 5 324 ? 102.535 122.047 154.651 1.00 171.56 ? 271 ASP R OD1 1 
ATOM 7837 O OD2 . ASP E 5 324 ? 101.439 123.872 155.189 1.00 171.28 ? 271 ASP R OD2 1 
ATOM 7838 N N   . THR E 5 325 ? 98.615  121.392 151.391 1.00 172.03 ? 272 THR R N   1 
ATOM 7839 C CA  . THR E 5 325 ? 97.339  120.971 150.825 1.00 171.17 ? 272 THR R CA  1 
ATOM 7840 C C   . THR E 5 325 ? 97.407  120.590 149.354 1.00 170.45 ? 272 THR R C   1 
ATOM 7841 O O   . THR E 5 325 ? 96.619  119.750 148.916 1.00 169.17 ? 272 THR R O   1 
ATOM 7842 C CB  . THR E 5 325 ? 96.290  122.077 150.995 1.00 169.45 ? 272 THR R CB  1 
ATOM 7843 O OG1 . THR E 5 325 ? 96.729  123.264 150.323 1.00 168.68 ? 272 THR R OG1 1 
ATOM 7844 C CG2 . THR E 5 325 ? 96.075  122.385 152.469 1.00 168.81 ? 272 THR R CG2 1 
ATOM 7845 N N   . ASP E 5 326 ? 98.318  121.181 148.581 1.00 165.53 ? 273 ASP R N   1 
ATOM 7846 C CA  . ASP E 5 326 ? 98.393  120.893 147.154 1.00 164.49 ? 273 ASP R CA  1 
ATOM 7847 C C   . ASP E 5 326 ? 99.141  119.605 146.841 1.00 163.73 ? 273 ASP R C   1 
ATOM 7848 O O   . ASP E 5 326 ? 99.165  119.192 145.677 1.00 163.01 ? 273 ASP R O   1 
ATOM 7849 C CB  . ASP E 5 326 ? 99.054  122.058 146.412 1.00 164.21 ? 273 ASP R CB  1 
ATOM 7850 C CG  . ASP E 5 326 ? 98.287  123.357 146.566 1.00 164.24 ? 273 ASP R CG  1 
ATOM 7851 O OD1 . ASP E 5 326 ? 97.231  123.350 147.232 1.00 164.99 ? 273 ASP R OD1 1 
ATOM 7852 O OD2 . ASP E 5 326 ? 98.742  124.385 146.022 1.00 163.28 ? 273 ASP R OD2 1 
ATOM 7853 N N   . LEU E 5 327 ? 99.753  118.967 147.841 1.00 161.06 ? 274 LEU R N   1 
ATOM 7854 C CA  . LEU E 5 327 ? 100.480 117.726 147.595 1.00 161.03 ? 274 LEU R CA  1 
ATOM 7855 C C   . LEU E 5 327 ? 99.548  116.586 147.204 1.00 160.69 ? 274 LEU R C   1 
ATOM 7856 O O   . LEU E 5 327 ? 99.949  115.691 146.451 1.00 159.63 ? 274 LEU R O   1 
ATOM 7857 C CB  . LEU E 5 327 ? 101.294 117.344 148.830 1.00 160.71 ? 274 LEU R CB  1 
ATOM 7858 C CG  . LEU E 5 327 ? 102.198 116.115 148.707 1.00 161.19 ? 274 LEU R CG  1 
ATOM 7859 C CD1 . LEU E 5 327 ? 103.231 116.317 147.609 1.00 160.38 ? 274 LEU R CD1 1 
ATOM 7860 C CD2 . LEU E 5 327 ? 102.873 115.808 150.035 1.00 160.16 ? 274 LEU R CD2 1 
ATOM 7861 N N   . TYR E 5 328 ? 98.306  116.599 147.693 1.00 154.88 ? 275 TYR R N   1 
ATOM 7862 C CA  . TYR E 5 328 ? 97.399  115.487 147.428 1.00 153.80 ? 275 TYR R CA  1 
ATOM 7863 C C   . TYR E 5 328 ? 96.921  115.483 145.980 1.00 153.12 ? 275 TYR R C   1 
ATOM 7864 O O   . TYR E 5 328 ? 97.056  114.473 145.278 1.00 152.69 ? 275 TYR R O   1 
ATOM 7865 C CB  . TYR E 5 328 ? 96.206  115.542 148.383 1.00 153.49 ? 275 TYR R CB  1 
ATOM 7866 C CG  . TYR E 5 328 ? 96.553  115.267 149.829 1.00 154.67 ? 275 TYR R CG  1 
ATOM 7867 C CD1 . TYR E 5 328 ? 96.591  113.968 150.318 1.00 153.40 ? 275 TYR R CD1 1 
ATOM 7868 C CD2 . TYR E 5 328 ? 96.834  116.306 150.706 1.00 154.56 ? 275 TYR R CD2 1 
ATOM 7869 C CE1 . TYR E 5 328 ? 96.905  113.711 151.640 1.00 153.60 ? 275 TYR R CE1 1 
ATOM 7870 C CE2 . TYR E 5 328 ? 97.149  116.059 152.030 1.00 153.59 ? 275 TYR R CE2 1 
ATOM 7871 C CZ  . TYR E 5 328 ? 97.182  114.760 152.491 1.00 153.70 ? 275 TYR R CZ  1 
ATOM 7872 O OH  . TYR E 5 328 ? 97.495  114.510 153.807 1.00 152.49 ? 275 TYR R OH  1 
ATOM 7873 N N   . TRP E 5 329 ? 96.362  116.602 145.511 1.00 144.75 ? 276 TRP R N   1 
ATOM 7874 C CA  . TRP E 5 329 ? 95.778  116.618 144.172 1.00 143.70 ? 276 TRP R CA  1 
ATOM 7875 C C   . TRP E 5 329 ? 96.840  116.433 143.095 1.00 143.08 ? 276 TRP R C   1 
ATOM 7876 O O   . TRP E 5 329 ? 96.580  115.806 142.063 1.00 142.43 ? 276 TRP R O   1 
ATOM 7877 C CB  . TRP E 5 329 ? 95.001  117.916 143.942 1.00 143.39 ? 276 TRP R CB  1 
ATOM 7878 C CG  . TRP E 5 329 ? 95.863  119.109 143.668 1.00 144.62 ? 276 TRP R CG  1 
ATOM 7879 C CD1 . TRP E 5 329 ? 96.345  119.998 144.581 1.00 144.18 ? 276 TRP R CD1 1 
ATOM 7880 C CD2 . TRP E 5 329 ? 96.347  119.544 142.390 1.00 144.94 ? 276 TRP R CD2 1 
ATOM 7881 N NE1 . TRP E 5 329 ? 97.098  120.961 143.954 1.00 144.57 ? 276 TRP R NE1 1 
ATOM 7882 C CE2 . TRP E 5 329 ? 97.116  120.704 142.608 1.00 145.35 ? 276 TRP R CE2 1 
ATOM 7883 C CE3 . TRP E 5 329 ? 96.206  119.064 141.084 1.00 142.55 ? 276 TRP R CE3 1 
ATOM 7884 C CZ2 . TRP E 5 329 ? 97.741  121.392 141.570 1.00 143.57 ? 276 TRP R CZ2 1 
ATOM 7885 C CZ3 . TRP E 5 329 ? 96.827  119.748 140.055 1.00 142.61 ? 276 TRP R CZ3 1 
ATOM 7886 C CH2 . TRP E 5 329 ? 97.585  120.899 140.304 1.00 143.22 ? 276 TRP R CH2 1 
ATOM 7887 N N   . PHE E 5 330 ? 98.039  116.977 143.310 1.00 137.47 ? 277 PHE R N   1 
ATOM 7888 C CA  . PHE E 5 330 ? 99.104  116.819 142.325 1.00 136.40 ? 277 PHE R CA  1 
ATOM 7889 C C   . PHE E 5 330 ? 99.529  115.362 142.194 1.00 136.46 ? 277 PHE R C   1 
ATOM 7890 O O   . PHE E 5 330 ? 99.800  114.887 141.086 1.00 137.07 ? 277 PHE R O   1 
ATOM 7891 C CB  . PHE E 5 330 ? 100.297 117.698 142.692 1.00 136.95 ? 277 PHE R CB  1 
ATOM 7892 C CG  . PHE E 5 330 ? 101.399 117.673 141.675 1.00 136.65 ? 277 PHE R CG  1 
ATOM 7893 C CD1 . PHE E 5 330 ? 101.308 118.432 140.522 1.00 136.70 ? 277 PHE R CD1 1 
ATOM 7894 C CD2 . PHE E 5 330 ? 102.527 116.896 141.874 1.00 136.92 ? 277 PHE R CD2 1 
ATOM 7895 C CE1 . PHE E 5 330 ? 102.319 118.415 139.583 1.00 136.79 ? 277 PHE R CE1 1 
ATOM 7896 C CE2 . PHE E 5 330 ? 103.543 116.875 140.938 1.00 136.53 ? 277 PHE R CE2 1 
ATOM 7897 C CZ  . PHE E 5 330 ? 103.439 117.637 139.792 1.00 136.91 ? 277 PHE R CZ  1 
ATOM 7898 N N   . THR E 5 331 ? 99.600  114.639 143.313 1.00 135.53 ? 278 THR R N   1 
ATOM 7899 C CA  . THR E 5 331 ? 99.948  113.223 143.254 1.00 135.81 ? 278 THR R CA  1 
ATOM 7900 C C   . THR E 5 331 ? 98.804  112.390 142.688 1.00 135.35 ? 278 THR R C   1 
ATOM 7901 O O   . THR E 5 331 ? 99.025  111.519 141.838 1.00 134.28 ? 278 THR R O   1 
ATOM 7902 C CB  . THR E 5 331 ? 100.340 112.723 144.644 1.00 137.27 ? 278 THR R CB  1 
ATOM 7903 O OG1 . THR E 5 331 ? 101.535 113.386 145.073 1.00 138.16 ? 278 THR R OG1 1 
ATOM 7904 C CG2 . THR E 5 331 ? 100.579 111.221 144.626 1.00 136.19 ? 278 THR R CG2 1 
ATOM 7905 N N   . LEU E 5 332 ? 97.575  112.644 143.144 1.00 129.66 ? 279 LEU R N   1 
ATOM 7906 C CA  . LEU E 5 332 ? 96.439  111.842 142.701 1.00 128.09 ? 279 LEU R CA  1 
ATOM 7907 C C   . LEU E 5 332 ? 96.165  112.021 141.213 1.00 126.65 ? 279 LEU R C   1 
ATOM 7908 O O   . LEU E 5 332 ? 95.885  111.044 140.509 1.00 127.84 ? 279 LEU R O   1 
ATOM 7909 C CB  . LEU E 5 332 ? 95.195  112.197 143.515 1.00 129.15 ? 279 LEU R CB  1 
ATOM 7910 C CG  . LEU E 5 332 ? 95.189  111.789 144.989 1.00 129.46 ? 279 LEU R CG  1 
ATOM 7911 C CD1 . LEU E 5 332 ? 93.940  112.311 145.678 1.00 128.65 ? 279 LEU R CD1 1 
ATOM 7912 C CD2 . LEU E 5 332 ? 95.285  110.281 145.127 1.00 127.04 ? 279 LEU R CD2 1 
ATOM 7913 N N   . TYR E 5 333 ? 96.236  113.257 140.714 1.00 111.93 ? 280 TYR R N   1 
ATOM 7914 C CA  . TYR E 5 333 ? 95.887  113.504 139.318 1.00 111.00 ? 280 TYR R CA  1 
ATOM 7915 C C   . TYR E 5 333 ? 96.903  112.881 138.369 1.00 111.19 ? 280 TYR R C   1 
ATOM 7916 O O   . TYR E 5 333 ? 96.536  112.405 137.288 1.00 109.85 ? 280 TYR R O   1 
ATOM 7917 C CB  . TYR E 5 333 ? 95.746  115.007 139.075 1.00 112.02 ? 280 TYR R CB  1 
ATOM 7918 C CG  . TYR E 5 333 ? 96.705  115.592 138.066 1.00 111.42 ? 280 TYR R CG  1 
ATOM 7919 C CD1 . TYR E 5 333 ? 97.950  116.061 138.455 1.00 113.67 ? 280 TYR R CD1 1 
ATOM 7920 C CD2 . TYR E 5 333 ? 96.352  115.706 136.730 1.00 109.61 ? 280 TYR R CD2 1 
ATOM 7921 C CE1 . TYR E 5 333 ? 98.823  116.605 137.540 1.00 113.83 ? 280 TYR R CE1 1 
ATOM 7922 C CE2 . TYR E 5 333 ? 97.219  116.250 135.808 1.00 110.58 ? 280 TYR R CE2 1 
ATOM 7923 C CZ  . TYR E 5 333 ? 98.452  116.696 136.218 1.00 112.74 ? 280 TYR R CZ  1 
ATOM 7924 O OH  . TYR E 5 333 ? 99.322  117.239 135.305 1.00 115.10 ? 280 TYR R OH  1 
ATOM 7925 N N   . GLN E 5 334 ? 98.183  112.873 138.747 1.00 113.52 ? 281 GLN R N   1 
ATOM 7926 C CA  . GLN E 5 334 ? 99.170  112.162 137.942 1.00 111.58 ? 281 GLN R CA  1 
ATOM 7927 C C   . GLN E 5 334 ? 98.935  110.659 137.994 1.00 111.75 ? 281 GLN R C   1 
ATOM 7928 O O   . GLN E 5 334 ? 99.099  109.964 136.986 1.00 114.25 ? 281 GLN R O   1 
ATOM 7929 C CB  . GLN E 5 334 ? 100.585 112.499 138.407 1.00 111.66 ? 281 GLN R CB  1 
ATOM 7930 C CG  . GLN E 5 334 ? 101.041 113.893 138.033 1.00 111.92 ? 281 GLN R CG  1 
ATOM 7931 C CD  . GLN E 5 334 ? 102.511 114.113 138.309 1.00 116.17 ? 281 GLN R CD  1 
ATOM 7932 O OE1 . GLN E 5 334 ? 103.073 115.148 137.953 1.00 118.47 ? 281 GLN R OE1 1 
ATOM 7933 N NE2 . GLN E 5 334 ? 103.147 113.135 138.946 1.00 113.12 ? 281 GLN R NE2 1 
ATOM 7934 N N   . PHE E 5 335 ? 98.560  110.142 139.164 1.00 101.26 ? 282 PHE R N   1 
ATOM 7935 C CA  . PHE E 5 335 ? 98.249  108.722 139.283 1.00 98.53  ? 282 PHE R CA  1 
ATOM 7936 C C   . PHE E 5 335 ? 97.045  108.352 138.428 1.00 99.38  ? 282 PHE R C   1 
ATOM 7937 O O   . PHE E 5 335 ? 97.033  107.298 137.782 1.00 103.48 ? 282 PHE R O   1 
ATOM 7938 C CB  . PHE E 5 335 ? 98.001  108.372 140.751 1.00 98.84  ? 282 PHE R CB  1 
ATOM 7939 C CG  . PHE E 5 335 ? 97.402  107.014 140.964 1.00 100.81 ? 282 PHE R CG  1 
ATOM 7940 C CD1 . PHE E 5 335 ? 98.188  105.879 140.904 1.00 99.99  ? 282 PHE R CD1 1 
ATOM 7941 C CD2 . PHE E 5 335 ? 96.054  106.874 141.243 1.00 100.73 ? 282 PHE R CD2 1 
ATOM 7942 C CE1 . PHE E 5 335 ? 97.640  104.630 141.107 1.00 97.57  ? 282 PHE R CE1 1 
ATOM 7943 C CE2 . PHE E 5 335 ? 95.502  105.628 141.446 1.00 99.18  ? 282 PHE R CE2 1 
ATOM 7944 C CZ  . PHE E 5 335 ? 96.296  104.505 141.378 1.00 97.85  ? 282 PHE R CZ  1 
ATOM 7945 N N   . PHE E 5 336 ? 96.024  109.209 138.410 1.00 89.98  ? 283 PHE R N   1 
ATOM 7946 C CA  . PHE E 5 336 ? 94.813  108.912 137.654 1.00 86.16  ? 283 PHE R CA  1 
ATOM 7947 C C   . PHE E 5 336 ? 95.057  109.002 136.152 1.00 86.52  ? 283 PHE R C   1 
ATOM 7948 O O   . PHE E 5 336 ? 94.666  108.106 135.396 1.00 91.55  ? 283 PHE R O   1 
ATOM 7949 C CB  . PHE E 5 336 ? 93.694  109.862 138.081 1.00 88.86  ? 283 PHE R CB  1 
ATOM 7950 C CG  . PHE E 5 336 ? 92.461  109.771 137.231 1.00 92.68  ? 283 PHE R CG  1 
ATOM 7951 C CD1 . PHE E 5 336 ? 91.557  108.738 137.406 1.00 93.56  ? 283 PHE R CD1 1 
ATOM 7952 C CD2 . PHE E 5 336 ? 92.200  110.726 136.262 1.00 90.86  ? 283 PHE R CD2 1 
ATOM 7953 C CE1 . PHE E 5 336 ? 90.419  108.654 136.625 1.00 92.00  ? 283 PHE R CE1 1 
ATOM 7954 C CE2 . PHE E 5 336 ? 91.066  110.649 135.478 1.00 91.47  ? 283 PHE R CE2 1 
ATOM 7955 C CZ  . PHE E 5 336 ? 90.174  109.611 135.660 1.00 91.79  ? 283 PHE R CZ  1 
ATOM 7956 N N   . LEU E 5 337 ? 95.706  110.076 135.699 1.00 84.31  ? 284 LEU R N   1 
ATOM 7957 C CA  . LEU E 5 337 ? 95.838  110.307 134.264 1.00 83.22  ? 284 LEU R CA  1 
ATOM 7958 C C   . LEU E 5 337 ? 96.934  109.464 133.627 1.00 81.24  ? 284 LEU R C   1 
ATOM 7959 O O   . LEU E 5 337 ? 96.843  109.141 132.439 1.00 82.42  ? 284 LEU R O   1 
ATOM 7960 C CB  . LEU E 5 337 ? 96.096  111.787 133.984 1.00 86.85  ? 284 LEU R CB  1 
ATOM 7961 C CG  . LEU E 5 337 ? 94.890  112.710 134.144 1.00 87.34  ? 284 LEU R CG  1 
ATOM 7962 C CD1 . LEU E 5 337 ? 95.245  114.126 133.732 1.00 85.60  ? 284 LEU R CD1 1 
ATOM 7963 C CD2 . LEU E 5 337 ? 93.709  112.196 133.337 1.00 83.67  ? 284 LEU R CD2 1 
ATOM 7964 N N   . ALA E 5 338 ? 97.974  109.105 134.379 1.00 81.97  ? 285 ALA R N   1 
ATOM 7965 C CA  . ALA E 5 338 ? 99.099  108.383 133.807 1.00 81.43  ? 285 ALA R CA  1 
ATOM 7966 C C   . ALA E 5 338 ? 99.146  106.910 134.177 1.00 85.60  ? 285 ALA R C   1 
ATOM 7967 O O   . ALA E 5 338 ? 99.798  106.140 133.467 1.00 86.91  ? 285 ALA R O   1 
ATOM 7968 C CB  . ALA E 5 338 ? 100.424 109.037 134.222 1.00 84.69  ? 285 ALA R CB  1 
ATOM 7969 N N   . PHE E 5 339 ? 98.512  106.500 135.273 1.00 86.17  ? 286 PHE R N   1 
ATOM 7970 C CA  . PHE E 5 339 ? 98.499  105.090 135.638 1.00 83.80  ? 286 PHE R CA  1 
ATOM 7971 C C   . PHE E 5 339 ? 97.100  104.505 135.737 1.00 80.83  ? 286 PHE R C   1 
ATOM 7972 O O   . PHE E 5 339 ? 96.821  103.481 135.107 1.00 86.64  ? 286 PHE R O   1 
ATOM 7973 C CB  . PHE E 5 339 ? 99.239  104.866 136.962 1.00 86.64  ? 286 PHE R CB  1 
ATOM 7974 C CG  . PHE E 5 339 ? 99.374  103.420 137.328 1.00 87.51  ? 286 PHE R CG  1 
ATOM 7975 C CD1 . PHE E 5 339 ? 100.379 102.648 136.774 1.00 86.62  ? 286 PHE R CD1 1 
ATOM 7976 C CD2 . PHE E 5 339 ? 98.490  102.828 138.212 1.00 87.78  ? 286 PHE R CD2 1 
ATOM 7977 C CE1 . PHE E 5 339 ? 100.505 101.317 137.100 1.00 88.28  ? 286 PHE R CE1 1 
ATOM 7978 C CE2 . PHE E 5 339 ? 98.611  101.495 138.542 1.00 87.89  ? 286 PHE R CE2 1 
ATOM 7979 C CZ  . PHE E 5 339 ? 99.620  100.739 137.986 1.00 89.07  ? 286 PHE R CZ  1 
ATOM 7980 N N   . ALA E 5 340 ? 96.209  105.124 136.512 1.00 79.15  ? 287 ALA R N   1 
ATOM 7981 C CA  . ALA E 5 340 ? 94.950  104.473 136.863 1.00 80.37  ? 287 ALA R CA  1 
ATOM 7982 C C   . ALA E 5 340 ? 94.022  104.354 135.660 1.00 78.34  ? 287 ALA R C   1 
ATOM 7983 O O   . ALA E 5 340 ? 93.660  103.246 135.250 1.00 80.82  ? 287 ALA R O   1 
ATOM 7984 C CB  . ALA E 5 340 ? 94.265  105.234 137.998 1.00 83.27  ? 287 ALA R CB  1 
ATOM 7985 N N   . LEU E 5 341 ? 93.619  105.485 135.086 1.00 71.02  ? 288 LEU R N   1 
ATOM 7986 C CA  . LEU E 5 341 ? 92.685  105.442 133.962 1.00 74.16  ? 288 LEU R CA  1 
ATOM 7987 C C   . LEU E 5 341 ? 93.237  104.696 132.754 1.00 77.63  ? 288 LEU R C   1 
ATOM 7988 O O   . LEU E 5 341 ? 92.524  103.831 132.218 1.00 82.53  ? 288 LEU R O   1 
ATOM 7989 C CB  . LEU E 5 341 ? 92.254  106.864 133.590 1.00 77.40  ? 288 LEU R CB  1 
ATOM 7990 C CG  . LEU E 5 341 ? 91.274  106.968 132.419 1.00 78.33  ? 288 LEU R CG  1 
ATOM 7991 C CD1 . LEU E 5 341 ? 90.001  106.197 132.719 1.00 75.40  ? 288 LEU R CD1 1 
ATOM 7992 C CD2 . LEU E 5 341 ? 90.961  108.420 132.102 1.00 76.72  ? 288 LEU R CD2 1 
ATOM 7993 N N   . PRO E 5 342 ? 94.455  104.965 132.266 1.00 67.02  ? 289 PRO R N   1 
ATOM 7994 C CA  . PRO E 5 342 ? 94.939  104.216 131.095 1.00 64.47  ? 289 PRO R CA  1 
ATOM 7995 C C   . PRO E 5 342 ? 95.064  102.721 131.324 1.00 71.35  ? 289 PRO R C   1 
ATOM 7996 O O   . PRO E 5 342 ? 94.841  101.946 130.387 1.00 77.83  ? 289 PRO R O   1 
ATOM 7997 C CB  . PRO E 5 342 ? 96.301  104.859 130.812 1.00 62.64  ? 289 PRO R CB  1 
ATOM 7998 C CG  . PRO E 5 342 ? 96.711  105.443 132.100 1.00 70.75  ? 289 PRO R CG  1 
ATOM 7999 C CD  . PRO E 5 342 ? 95.454  105.947 132.717 1.00 71.98  ? 289 PRO R CD  1 
ATOM 8000 N N   . PHE E 5 343 ? 95.422  102.287 132.534 1.00 67.41  ? 290 PHE R N   1 
ATOM 8001 C CA  . PHE E 5 343 ? 95.561  100.855 132.789 1.00 66.75  ? 290 PHE R CA  1 
ATOM 8002 C C   . PHE E 5 343 ? 94.222  100.140 132.680 1.00 68.88  ? 290 PHE R C   1 
ATOM 8003 O O   . PHE E 5 343 ? 94.148  99.030  132.142 1.00 71.54  ? 290 PHE R O   1 
ATOM 8004 C CB  . PHE E 5 343 ? 96.182  100.619 134.163 1.00 64.45  ? 290 PHE R CB  1 
ATOM 8005 C CG  . PHE E 5 343 ? 96.287  99.173  134.540 1.00 65.49  ? 290 PHE R CG  1 
ATOM 8006 C CD1 . PHE E 5 343 ? 97.288  98.378  134.011 1.00 68.64  ? 290 PHE R CD1 1 
ATOM 8007 C CD2 . PHE E 5 343 ? 95.393  98.609  135.431 1.00 68.32  ? 290 PHE R CD2 1 
ATOM 8008 C CE1 . PHE E 5 343 ? 97.389  97.048  134.358 1.00 70.72  ? 290 PHE R CE1 1 
ATOM 8009 C CE2 . PHE E 5 343 ? 95.490  97.280  135.783 1.00 70.74  ? 290 PHE R CE2 1 
ATOM 8010 C CZ  . PHE E 5 343 ? 96.489  96.498  135.245 1.00 69.26  ? 290 PHE R CZ  1 
ATOM 8011 N N   . VAL E 5 344 ? 93.155  100.753 133.193 1.00 60.95  ? 291 VAL R N   1 
ATOM 8012 C CA  . VAL E 5 344 ? 91.833  100.141 133.100 1.00 60.10  ? 291 VAL R CA  1 
ATOM 8013 C C   . VAL E 5 344 ? 91.399  100.031 131.646 1.00 65.31  ? 291 VAL R C   1 
ATOM 8014 O O   . VAL E 5 344 ? 90.864  99.002  131.218 1.00 65.60  ? 291 VAL R O   1 
ATOM 8015 C CB  . VAL E 5 344 ? 90.816  100.937 133.938 1.00 61.54  ? 291 VAL R CB  1 
ATOM 8016 C CG1 . VAL E 5 344 ? 89.437  100.321 133.819 1.00 64.60  ? 291 VAL R CG1 1 
ATOM 8017 C CG2 . VAL E 5 344 ? 91.253  100.976 135.390 1.00 59.85  ? 291 VAL R CG2 1 
ATOM 8018 N N   . VAL E 5 345 ? 91.625  101.087 130.863 1.00 65.31  ? 292 VAL R N   1 
ATOM 8019 C CA  . VAL E 5 345 ? 91.250  101.066 129.451 1.00 57.46  ? 292 VAL R CA  1 
ATOM 8020 C C   . VAL E 5 345 ? 92.059  100.019 128.697 1.00 57.71  ? 292 VAL R C   1 
ATOM 8021 O O   . VAL E 5 345 ? 91.519  99.275  127.871 1.00 65.69  ? 292 VAL R O   1 
ATOM 8022 C CB  . VAL E 5 345 ? 91.417  102.465 128.834 1.00 56.39  ? 292 VAL R CB  1 
ATOM 8023 C CG1 . VAL E 5 345 ? 91.065  102.437 127.361 1.00 59.68  ? 292 VAL R CG1 1 
ATOM 8024 C CG2 . VAL E 5 345 ? 90.548  103.465 129.570 1.00 59.23  ? 292 VAL R CG2 1 
ATOM 8025 N N   . ILE E 5 346 ? 93.365  99.947  128.961 1.00 51.00  ? 293 ILE R N   1 
ATOM 8026 C CA  . ILE E 5 346 ? 94.201  98.946  128.303 1.00 53.49  ? 293 ILE R CA  1 
ATOM 8027 C C   . ILE E 5 346 ? 93.769  97.543  128.710 1.00 60.00  ? 293 ILE R C   1 
ATOM 8028 O O   . ILE E 5 346 ? 93.641  96.646  127.870 1.00 61.39  ? 293 ILE R O   1 
ATOM 8029 C CB  . ILE E 5 346 ? 95.687  99.194  128.617 1.00 51.99  ? 293 ILE R CB  1 
ATOM 8030 C CG1 . ILE E 5 346 ? 96.179  100.460 127.920 1.00 58.11  ? 293 ILE R CG1 1 
ATOM 8031 C CG2 . ILE E 5 346 ? 96.531  98.004  128.196 1.00 52.51  ? 293 ILE R CG2 1 
ATOM 8032 C CD1 . ILE E 5 346 ? 97.628  100.774 128.194 1.00 60.03  ? 293 ILE R CD1 1 
ATOM 8033 N N   . THR E 5 347 ? 93.534  97.333  130.006 1.00 58.22  ? 294 THR R N   1 
ATOM 8034 C CA  . THR E 5 347 ? 93.107  96.017  130.472 1.00 57.09  ? 294 THR R CA  1 
ATOM 8035 C C   . THR E 5 347 ? 91.746  95.643  129.900 1.00 60.88  ? 294 THR R C   1 
ATOM 8036 O O   . THR E 5 347 ? 91.543  94.507  129.459 1.00 61.89  ? 294 THR R O   1 
ATOM 8037 C CB  . THR E 5 347 ? 93.074  95.984  131.999 1.00 62.51  ? 294 THR R CB  1 
ATOM 8038 O OG1 . THR E 5 347 ? 94.380  96.273  132.512 1.00 67.56  ? 294 THR R OG1 1 
ATOM 8039 C CG2 . THR E 5 347 ? 92.636  94.618  132.498 1.00 58.27  ? 294 THR R CG2 1 
ATOM 8040 N N   . ALA E 5 348 ? 90.804  96.587  129.891 1.00 54.82  ? 295 ALA R N   1 
ATOM 8041 C CA  . ALA E 5 348 ? 89.478  96.301  129.354 1.00 52.98  ? 295 ALA R CA  1 
ATOM 8042 C C   . ALA E 5 348 ? 89.531  96.030  127.857 1.00 57.47  ? 295 ALA R C   1 
ATOM 8043 O O   . ALA E 5 348 ? 88.790  95.183  127.348 1.00 61.02  ? 295 ALA R O   1 
ATOM 8044 C CB  . ALA E 5 348 ? 88.529  97.457  129.654 1.00 52.66  ? 295 ALA R CB  1 
ATOM 8045 N N   . ALA E 5 349 ? 90.389  96.750  127.132 1.00 52.79  ? 296 ALA R N   1 
ATOM 8046 C CA  . ALA E 5 349 ? 90.471  96.562  125.688 1.00 39.94  ? 296 ALA R CA  1 
ATOM 8047 C C   . ALA E 5 349 ? 90.988  95.176  125.330 1.00 48.22  ? 296 ALA R C   1 
ATOM 8048 O O   . ALA E 5 349 ? 90.447  94.521  124.434 1.00 61.79  ? 296 ALA R O   1 
ATOM 8049 C CB  . ALA E 5 349 ? 91.359  97.638  125.069 1.00 47.18  ? 296 ALA R CB  1 
ATOM 8050 N N   . TYR E 5 350 ? 92.030  94.707  126.019 1.00 52.68  ? 297 TYR R N   1 
ATOM 8051 C CA  . TYR E 5 350 ? 92.664  93.451  125.634 1.00 52.41  ? 297 TYR R CA  1 
ATOM 8052 C C   . TYR E 5 350 ? 91.869  92.227  126.067 1.00 54.69  ? 297 TYR R C   1 
ATOM 8053 O O   . TYR E 5 350 ? 91.925  91.196  125.389 1.00 61.33  ? 297 TYR R O   1 
ATOM 8054 C CB  . TYR E 5 350 ? 94.086  93.385  126.183 1.00 46.28  ? 297 TYR R CB  1 
ATOM 8055 C CG  . TYR E 5 350 ? 95.069  94.151  125.333 1.00 50.20  ? 297 TYR R CG  1 
ATOM 8056 C CD1 . TYR E 5 350 ? 95.497  93.646  124.116 1.00 53.79  ? 297 TYR R CD1 1 
ATOM 8057 C CD2 . TYR E 5 350 ? 95.563  95.378  125.740 1.00 54.05  ? 297 TYR R CD2 1 
ATOM 8058 C CE1 . TYR E 5 350 ? 96.389  94.340  123.331 1.00 54.66  ? 297 TYR R CE1 1 
ATOM 8059 C CE2 . TYR E 5 350 ? 96.457  96.079  124.962 1.00 52.05  ? 297 TYR R CE2 1 
ATOM 8060 C CZ  . TYR E 5 350 ? 96.867  95.555  123.758 1.00 53.62  ? 297 TYR R CZ  1 
ATOM 8061 O OH  . TYR E 5 350 ? 97.757  96.251  122.977 1.00 55.69  ? 297 TYR R OH  1 
ATOM 8062 N N   . VAL E 5 351 ? 91.140  92.297  127.183 1.00 60.40  ? 298 VAL R N   1 
ATOM 8063 C CA  . VAL E 5 351 ? 90.316  91.157  127.569 1.00 59.36  ? 298 VAL R CA  1 
ATOM 8064 C C   . VAL E 5 351 ? 89.164  90.981  126.587 1.00 63.43  ? 298 VAL R C   1 
ATOM 8065 O O   . VAL E 5 351 ? 88.769  89.854  126.271 1.00 71.77  ? 298 VAL R O   1 
ATOM 8066 C CB  . VAL E 5 351 ? 89.822  91.296  129.022 1.00 56.22  ? 298 VAL R CB  1 
ATOM 8067 C CG1 . VAL E 5 351 ? 91.001  91.292  129.980 1.00 56.25  ? 298 VAL R CG1 1 
ATOM 8068 C CG2 . VAL E 5 351 ? 88.989  92.551  129.203 1.00 57.06  ? 298 VAL R CG2 1 
ATOM 8069 N N   . ARG E 5 352 ? 88.614  92.087  126.079 1.00 56.86  ? 299 ARG R N   1 
ATOM 8070 C CA  . ARG E 5 352 ? 87.597  91.990  125.038 1.00 55.20  ? 299 ARG R CA  1 
ATOM 8071 C C   . ARG E 5 352 ? 88.177  91.431  123.746 1.00 55.74  ? 299 ARG R C   1 
ATOM 8072 O O   . ARG E 5 352 ? 87.477  90.730  123.008 1.00 62.61  ? 299 ARG R O   1 
ATOM 8073 C CB  . ARG E 5 352 ? 86.961  93.355  124.786 1.00 60.45  ? 299 ARG R CB  1 
ATOM 8074 C CG  . ARG E 5 352 ? 86.171  93.908  125.961 1.00 62.69  ? 299 ARG R CG  1 
ATOM 8075 C CD  . ARG E 5 352 ? 84.889  93.129  126.218 1.00 66.29  ? 299 ARG R CD  1 
ATOM 8076 N NE  . ARG E 5 352 ? 83.918  93.287  125.141 1.00 69.89  ? 299 ARG R NE  1 
ATOM 8077 C CZ  . ARG E 5 352 ? 83.703  92.391  124.187 1.00 68.73  ? 299 ARG R CZ  1 
ATOM 8078 N NH1 . ARG E 5 352 ? 84.367  91.249  124.150 1.00 65.88  ? 299 ARG R NH1 1 
ATOM 8079 N NH2 . ARG E 5 352 ? 82.799  92.650  123.247 1.00 62.82  ? 299 ARG R NH2 1 
ATOM 8080 N N   . ILE E 5 353 ? 89.442  91.737  123.450 1.00 49.39  ? 300 ILE R N   1 
ATOM 8081 C CA  . ILE E 5 353 ? 90.086  91.162  122.273 1.00 49.44  ? 300 ILE R CA  1 
ATOM 8082 C C   . ILE E 5 353 ? 90.178  89.651  122.410 1.00 55.07  ? 300 ILE R C   1 
ATOM 8083 O O   . ILE E 5 353 ? 89.903  88.908  121.461 1.00 63.43  ? 300 ILE R O   1 
ATOM 8084 C CB  . ILE E 5 353 ? 91.474  91.793  122.057 1.00 44.18  ? 300 ILE R CB  1 
ATOM 8085 C CG1 . ILE E 5 353 ? 91.343  93.251  121.631 1.00 49.52  ? 300 ILE R CG1 1 
ATOM 8086 C CG2 . ILE E 5 353 ? 92.269  91.010  121.027 1.00 44.11  ? 300 ILE R CG2 1 
ATOM 8087 C CD1 . ILE E 5 353 ? 92.671  93.935  121.434 1.00 53.13  ? 300 ILE R CD1 1 
ATOM 8088 N N   . LEU E 5 354 ? 90.561  89.171  123.594 1.00 52.77  ? 301 LEU R N   1 
ATOM 8089 C CA  . LEU E 5 354 ? 90.684  87.733  123.803 1.00 59.53  ? 301 LEU R CA  1 
ATOM 8090 C C   . LEU E 5 354 ? 89.332  87.036  123.756 1.00 62.51  ? 301 LEU R C   1 
ATOM 8091 O O   . LEU E 5 354 ? 89.256  85.862  123.378 1.00 61.82  ? 301 LEU R O   1 
ATOM 8092 C CB  . LEU E 5 354 ? 91.380  87.458  125.134 1.00 55.86  ? 301 LEU R CB  1 
ATOM 8093 C CG  . LEU E 5 354 ? 92.790  88.033  125.250 1.00 59.27  ? 301 LEU R CG  1 
ATOM 8094 C CD1 . LEU E 5 354 ? 93.401  87.690  126.594 1.00 60.08  ? 301 LEU R CD1 1 
ATOM 8095 C CD2 . LEU E 5 354 ? 93.658  87.525  124.119 1.00 55.46  ? 301 LEU R CD2 1 
ATOM 8096 N N   . GLN E 5 355 ? 88.260  87.731  124.131 1.00 59.26  ? 302 GLN R N   1 
ATOM 8097 C CA  . GLN E 5 355 ? 86.927  87.148  124.115 1.00 60.76  ? 302 GLN R CA  1 
ATOM 8098 C C   . GLN E 5 355 ? 86.211  87.320  122.782 1.00 63.42  ? 302 GLN R C   1 
ATOM 8099 O O   . GLN E 5 355 ? 85.134  86.743  122.598 1.00 62.18  ? 302 GLN R O   1 
ATOM 8100 C CB  . GLN E 5 355 ? 86.074  87.760  125.227 1.00 55.87  ? 302 GLN R CB  1 
ATOM 8101 C CG  . GLN E 5 355 ? 86.620  87.532  126.621 1.00 58.47  ? 302 GLN R CG  1 
ATOM 8102 C CD  . GLN E 5 355 ? 85.823  88.260  127.680 1.00 65.15  ? 302 GLN R CD  1 
ATOM 8103 O OE1 . GLN E 5 355 ? 84.894  89.006  127.371 1.00 66.54  ? 302 GLN R OE1 1 
ATOM 8104 N NE2 . GLN E 5 355 ? 86.180  88.046  128.940 1.00 65.08  ? 302 GLN R NE2 1 
ATOM 8105 N N   . ARG E 5 356 ? 86.775  88.089  121.855 1.00 70.62  ? 303 ARG R N   1 
ATOM 8106 C CA  . ARG E 5 356 ? 86.152  88.344  120.562 1.00 70.23  ? 303 ARG R CA  1 
ATOM 8107 C C   . ARG E 5 356 ? 87.182  88.258  119.446 1.00 74.52  ? 303 ARG R C   1 
ATOM 8108 O O   . ARG E 5 356 ? 87.206  89.090  118.534 1.00 75.27  ? 303 ARG R O   1 
ATOM 8109 C CB  . ARG E 5 356 ? 85.455  89.703  120.546 1.00 69.97  ? 303 ARG R CB  1 
ATOM 8110 C CG  . ARG E 5 356 ? 84.109  89.721  121.242 1.00 67.46  ? 303 ARG R CG  1 
ATOM 8111 C CD  . ARG E 5 356 ? 83.031  89.106  120.369 1.00 67.68  ? 303 ARG R CD  1 
ATOM 8112 N NE  . ARG E 5 356 ? 82.651  89.982  119.268 1.00 72.73  ? 303 ARG R NE  1 
ATOM 8113 C CZ  . ARG E 5 356 ? 83.132  89.892  118.035 1.00 76.07  ? 303 ARG R CZ  1 
ATOM 8114 N NH1 . ARG E 5 356 ? 84.014  88.964  117.703 1.00 72.04  ? 303 ARG R NH1 1 
ATOM 8115 N NH2 . ARG E 5 356 ? 82.713  90.753  117.111 1.00 73.20  ? 303 ARG R NH2 1 
ATOM 8116 N N   . MET E 5 357 ? 88.053  87.252  119.503 1.00 74.85  ? 304 MET R N   1 
ATOM 8117 C CA  . MET E 5 357 ? 89.082  87.060  118.490 1.00 74.92  ? 304 MET R CA  1 
ATOM 8118 C C   . MET E 5 357 ? 88.796  85.874  117.580 1.00 79.74  ? 304 MET R C   1 
ATOM 8119 O O   . MET E 5 357 ? 89.643  85.521  116.754 1.00 79.26  ? 304 MET R O   1 
ATOM 8120 C CB  . MET E 5 357 ? 90.446  86.886  119.154 1.00 68.72  ? 304 MET R CB  1 
ATOM 8121 C CG  . MET E 5 357 ? 90.481  85.780  120.184 1.00 72.82  ? 304 MET R CG  1 
ATOM 8122 S SD  . MET E 5 357 ? 92.109  85.613  120.921 1.00 88.07  ? 304 MET R SD  1 
ATOM 8123 C CE  . MET E 5 357 ? 93.080  85.374  119.444 1.00 72.34  ? 304 MET R CE  1 
ATOM 8124 N N   . THR E 5 358 ? 87.627  85.252  117.709 1.00 85.22  ? 305 THR R N   1 
ATOM 8125 C CA  . THR E 5 358 ? 87.271  84.088  116.912 1.00 86.05  ? 305 THR R CA  1 
ATOM 8126 C C   . THR E 5 358 ? 85.819  84.206  116.481 1.00 84.50  ? 305 THR R C   1 
ATOM 8127 O O   . THR E 5 358 ? 85.007  84.852  117.148 1.00 83.35  ? 305 THR R O   1 
ATOM 8128 C CB  . THR E 5 358 ? 87.476  82.774  117.680 1.00 82.61  ? 305 THR R CB  1 
ATOM 8129 O OG1 . THR E 5 358 ? 86.834  82.858  118.959 1.00 79.51  ? 305 THR R OG1 1 
ATOM 8130 C CG2 . THR E 5 358 ? 88.959  82.481  117.870 1.00 80.07  ? 305 THR R CG2 1 
ATOM 8131 N N   . SER E 5 359 ? 85.503  83.575  115.358 1.00 87.98  ? 306 SER R N   1 
ATOM 8132 C CA  . SER E 5 359 ? 84.152  83.547  114.823 1.00 87.78  ? 306 SER R CA  1 
ATOM 8133 C C   . SER E 5 359 ? 83.482  82.215  115.139 1.00 85.40  ? 306 SER R C   1 
ATOM 8134 O O   . SER E 5 359 ? 84.137  81.226  115.476 1.00 84.12  ? 306 SER R O   1 
ATOM 8135 C CB  . SER E 5 359 ? 84.168  83.784  113.310 1.00 83.54  ? 306 SER R CB  1 
ATOM 8136 O OG  . SER E 5 359 ? 82.855  83.813  112.781 1.00 86.52  ? 306 SER R OG  1 
ATOM 8137 N N   . SER E 5 360 ? 82.152  82.208  115.037 1.00 89.44  ? 307 SER R N   1 
ATOM 8138 C CA  . SER E 5 360 ? 81.401  80.979  115.271 1.00 90.50  ? 307 SER R CA  1 
ATOM 8139 C C   . SER E 5 360 ? 81.726  79.921  114.225 1.00 92.12  ? 307 SER R C   1 
ATOM 8140 O O   . SER E 5 360 ? 81.619  78.721  114.499 1.00 89.68  ? 307 SER R O   1 
ATOM 8141 C CB  . SER E 5 360 ? 79.903  81.278  115.281 1.00 90.22  ? 307 SER R CB  1 
ATOM 8142 O OG  . SER E 5 360 ? 79.502  81.895  114.070 1.00 89.14  ? 307 SER R OG  1 
ATOM 8143 N N   . VAL E 5 361 ? 82.119  80.348  113.025 1.00 83.86  ? 308 VAL R N   1 
ATOM 8144 C CA  . VAL E 5 361 ? 82.445  79.414  111.954 1.00 83.79  ? 308 VAL R CA  1 
ATOM 8145 C C   . VAL E 5 361 ? 83.855  78.852  112.119 1.00 83.66  ? 308 VAL R C   1 
ATOM 8146 O O   . VAL E 5 361 ? 84.134  77.728  111.682 1.00 81.06  ? 308 VAL R O   1 
ATOM 8147 C CB  . VAL E 5 361 ? 82.242  80.113  110.597 1.00 81.76  ? 308 VAL R CB  1 
ATOM 8148 C CG1 . VAL E 5 361 ? 83.139  79.529  109.522 1.00 80.86  ? 308 VAL R CG1 1 
ATOM 8149 C CG2 . VAL E 5 361 ? 80.782  80.013  110.178 1.00 81.92  ? 308 VAL R CG2 1 
ATOM 8150 N N   . ALA E 5 362 ? 84.742  79.590  112.778 1.00 87.57  ? 309 ALA R N   1 
ATOM 8151 C CA  . ALA E 5 362 ? 86.136  79.179  112.880 1.00 88.23  ? 309 ALA R CA  1 
ATOM 8152 C C   . ALA E 5 362 ? 86.246  77.832  113.590 1.00 89.30  ? 309 ALA R C   1 
ATOM 8153 O O   . ALA E 5 362 ? 85.622  77.637  114.643 1.00 86.82  ? 309 ALA R O   1 
ATOM 8154 C CB  . ALA E 5 362 ? 86.952  80.233  113.626 1.00 83.07  ? 309 ALA R CB  1 
ATOM 8155 N N   . PRO E 5 363 ? 87.015  76.886  113.053 1.00 95.00  ? 310 PRO R N   1 
ATOM 8156 C CA  . PRO E 5 363 ? 87.184  75.547  113.662 1.00 94.34  ? 310 PRO R CA  1 
ATOM 8157 C C   . PRO E 5 363 ? 88.111  75.560  114.875 1.00 96.10  ? 310 PRO R C   1 
ATOM 8158 O O   . PRO E 5 363 ? 89.310  75.295  114.801 1.00 94.88  ? 310 PRO R O   1 
ATOM 8159 C CB  . PRO E 5 363 ? 87.758  74.727  112.505 1.00 91.56  ? 310 PRO R CB  1 
ATOM 8160 C CG  . PRO E 5 363 ? 88.521  75.724  111.701 1.00 91.03  ? 310 PRO R CG  1 
ATOM 8161 C CD  . PRO E 5 363 ? 87.742  77.007  111.777 1.00 90.77  ? 310 PRO R CD  1 
ATOM 8162 N N   . ALA E 5 364 ? 87.527  75.883  116.033 1.00 100.85 ? 311 ALA R N   1 
ATOM 8163 C CA  . ALA E 5 364 ? 88.305  76.033  117.262 1.00 100.45 ? 311 ALA R CA  1 
ATOM 8164 C C   . ALA E 5 364 ? 89.123  74.788  117.583 1.00 100.28 ? 311 ALA R C   1 
ATOM 8165 O O   . ALA E 5 364 ? 90.182  74.890  118.212 1.00 98.06  ? 311 ALA R O   1 
ATOM 8166 C CB  . ALA E 5 364 ? 87.378  76.371  118.429 1.00 99.47  ? 311 ALA R CB  1 
ATOM 8167 N N   . SER E 5 365 ? 88.652  73.610  117.171 1.00 100.22 ? 312 SER R N   1 
ATOM 8168 C CA  . SER E 5 365 ? 89.402  72.385  117.418 1.00 101.09 ? 312 SER R CA  1 
ATOM 8169 C C   . SER E 5 365 ? 90.688  72.316  116.604 1.00 101.34 ? 312 SER R C   1 
ATOM 8170 O O   . SER E 5 365 ? 91.586  71.545  116.957 1.00 102.10 ? 312 SER R O   1 
ATOM 8171 C CB  . SER E 5 365 ? 88.535  71.163  117.115 1.00 97.53  ? 312 SER R CB  1 
ATOM 8172 O OG  . SER E 5 365 ? 88.160  71.130  115.749 1.00 99.56  ? 312 SER R OG  1 
ATOM 8173 N N   . GLN E 5 366 ? 90.797  73.096  115.532 1.00 90.12  ? 313 GLN R N   1 
ATOM 8174 C CA  . GLN E 5 366 ? 91.992  73.060  114.701 1.00 90.84  ? 313 GLN R CA  1 
ATOM 8175 C C   . GLN E 5 366 ? 93.176  73.683  115.433 1.00 88.61  ? 313 GLN R C   1 
ATOM 8176 O O   . GLN E 5 366 ? 93.020  74.565  116.280 1.00 85.25  ? 313 GLN R O   1 
ATOM 8177 C CB  . GLN E 5 366 ? 91.742  73.786  113.378 1.00 89.80  ? 313 GLN R CB  1 
ATOM 8178 C CG  . GLN E 5 366 ? 92.821  73.565  112.330 1.00 91.78  ? 313 GLN R CG  1 
ATOM 8179 C CD  . GLN E 5 366 ? 92.450  74.134  110.975 1.00 89.16  ? 313 GLN R CD  1 
ATOM 8180 O OE1 . GLN E 5 366 ? 91.298  74.489  110.733 1.00 84.65  ? 313 GLN R OE1 1 
ATOM 8181 N NE2 . GLN E 5 366 ? 93.430  74.223  110.084 1.00 87.04  ? 313 GLN R NE2 1 
ATOM 8182 N N   . ARG E 5 367 ? 94.375  73.199  115.098 1.00 85.83  ? 314 ARG R N   1 
ATOM 8183 C CA  . ARG E 5 367 ? 95.584  73.667  115.767 1.00 87.52  ? 314 ARG R CA  1 
ATOM 8184 C C   . ARG E 5 367 ? 95.843  75.142  115.492 1.00 89.35  ? 314 ARG R C   1 
ATOM 8185 O O   . ARG E 5 367 ? 96.318  75.869  116.371 1.00 91.23  ? 314 ARG R O   1 
ATOM 8186 C CB  . ARG E 5 367 ? 96.781  72.823  115.333 1.00 86.63  ? 314 ARG R CB  1 
ATOM 8187 N N   . SER E 5 368 ? 95.546  75.602  114.274 1.00 86.08  ? 315 SER R N   1 
ATOM 8188 C CA  . SER E 5 368 ? 95.804  76.996  113.928 1.00 80.93  ? 315 SER R CA  1 
ATOM 8189 C C   . SER E 5 368 ? 94.981  77.945  114.790 1.00 79.15  ? 315 SER R C   1 
ATOM 8190 O O   . SER E 5 368 ? 95.481  78.987  115.228 1.00 80.01  ? 315 SER R O   1 
ATOM 8191 C CB  . SER E 5 368 ? 95.513  77.231  112.448 1.00 81.06  ? 315 SER R CB  1 
ATOM 8192 O OG  . SER E 5 368 ? 94.161  76.941  112.148 1.00 83.96  ? 315 SER R OG  1 
ATOM 8193 N N   . ILE E 5 369 ? 93.713  77.611  115.033 1.00 78.71  ? 316 ILE R N   1 
ATOM 8194 C CA  . ILE E 5 369 ? 92.883  78.446  115.895 1.00 79.48  ? 316 ILE R CA  1 
ATOM 8195 C C   . ILE E 5 369 ? 93.393  78.409  117.329 1.00 84.05  ? 316 ILE R C   1 
ATOM 8196 O O   . ILE E 5 369 ? 93.466  79.443  118.003 1.00 84.20  ? 316 ILE R O   1 
ATOM 8197 C CB  . ILE E 5 369 ? 91.411  78.011  115.808 1.00 80.70  ? 316 ILE R CB  1 
ATOM 8198 C CG1 . ILE E 5 369 ? 90.950  77.991  114.352 1.00 83.28  ? 316 ILE R CG1 1 
ATOM 8199 C CG2 . ILE E 5 369 ? 90.538  78.944  116.626 1.00 78.73  ? 316 ILE R CG2 1 
ATOM 8200 C CD1 . ILE E 5 369 ? 90.950  79.340  113.695 1.00 80.78  ? 316 ILE R CD1 1 
ATOM 8201 N N   . ARG E 5 370 ? 93.749  77.220  117.822 1.00 86.80  ? 317 ARG R N   1 
ATOM 8202 C CA  . ARG E 5 370 ? 94.293  77.113  119.172 1.00 83.28  ? 317 ARG R CA  1 
ATOM 8203 C C   . ARG E 5 370 ? 95.613  77.862  119.294 1.00 76.68  ? 317 ARG R C   1 
ATOM 8204 O O   . ARG E 5 370 ? 95.864  78.532  120.301 1.00 78.42  ? 317 ARG R O   1 
ATOM 8205 C CB  . ARG E 5 370 ? 94.472  75.644  119.552 1.00 80.46  ? 317 ARG R CB  1 
ATOM 8206 N N   . LEU E 5 371 ? 96.470  77.759  118.276 1.00 67.93  ? 318 LEU R N   1 
ATOM 8207 C CA  . LEU E 5 371 ? 97.739  78.477  118.302 1.00 71.09  ? 318 LEU R CA  1 
ATOM 8208 C C   . LEU E 5 371 ? 97.535  79.985  118.242 1.00 78.54  ? 318 LEU R C   1 
ATOM 8209 O O   . LEU E 5 371 ? 98.333  80.738  118.810 1.00 76.83  ? 318 LEU R O   1 
ATOM 8210 C CB  . LEU E 5 371 ? 98.624  78.016  117.145 1.00 74.35  ? 318 LEU R CB  1 
ATOM 8211 C CG  . LEU E 5 371 ? 100.035 78.601  117.075 1.00 78.61  ? 318 LEU R CG  1 
ATOM 8212 C CD1 . LEU E 5 371 ? 100.838 78.204  118.302 1.00 77.58  ? 318 LEU R CD1 1 
ATOM 8213 C CD2 . LEU E 5 371 ? 100.739 78.158  115.803 1.00 74.92  ? 318 LEU R CD2 1 
ATOM 8214 N N   . ARG E 5 372 ? 96.487  80.444  117.555 1.00 76.52  ? 319 ARG R N   1 
ATOM 8215 C CA  . ARG E 5 372 ? 96.213  81.876  117.494 1.00 67.51  ? 319 ARG R CA  1 
ATOM 8216 C C   . ARG E 5 372 ? 95.813  82.423  118.858 1.00 68.77  ? 319 ARG R C   1 
ATOM 8217 O O   . ARG E 5 372 ? 96.302  83.475  119.282 1.00 74.63  ? 319 ARG R O   1 
ATOM 8218 C CB  . ARG E 5 372 ? 95.122  82.165  116.463 1.00 70.44  ? 319 ARG R CB  1 
ATOM 8219 C CG  . ARG E 5 372 ? 94.340  83.432  116.758 1.00 71.69  ? 319 ARG R CG  1 
ATOM 8220 C CD  . ARG E 5 372 ? 93.712  84.043  115.523 1.00 65.97  ? 319 ARG R CD  1 
ATOM 8221 N NE  . ARG E 5 372 ? 92.869  83.104  114.797 1.00 67.37  ? 319 ARG R NE  1 
ATOM 8222 C CZ  . ARG E 5 372 ? 91.978  83.460  113.884 1.00 65.62  ? 319 ARG R CZ  1 
ATOM 8223 N NH1 . ARG E 5 372 ? 91.760  84.730  113.592 1.00 69.47  ? 319 ARG R NH1 1 
ATOM 8224 N NH2 . ARG E 5 372 ? 91.285  82.519  113.252 1.00 68.43  ? 319 ARG R NH2 1 
ATOM 8225 N N   . THR E 5 373 ? 94.928  81.719  119.564 1.00 69.37  ? 320 THR R N   1 
ATOM 8226 C CA  . THR E 5 373 ? 94.487  82.199  120.870 1.00 71.21  ? 320 THR R CA  1 
ATOM 8227 C C   . THR E 5 373 ? 95.629  82.187  121.877 1.00 68.59  ? 320 THR R C   1 
ATOM 8228 O O   . THR E 5 373 ? 95.739  83.092  122.711 1.00 71.21  ? 320 THR R O   1 
ATOM 8229 C CB  . THR E 5 373 ? 93.316  81.354  121.372 1.00 72.04  ? 320 THR R CB  1 
ATOM 8230 O OG1 . THR E 5 373 ? 92.289  81.319  120.374 1.00 72.81  ? 320 THR R OG1 1 
ATOM 8231 C CG2 . THR E 5 373 ? 92.743  81.944  122.648 1.00 68.73  ? 320 THR R CG2 1 
ATOM 8232 N N   . LYS E 5 374 ? 96.490  81.170  121.816 1.00 72.01  ? 321 LYS R N   1 
ATOM 8233 C CA  . LYS E 5 374 ? 97.580  81.064  122.779 1.00 70.12  ? 321 LYS R CA  1 
ATOM 8234 C C   . LYS E 5 374 ? 98.602  82.180  122.591 1.00 68.37  ? 321 LYS R C   1 
ATOM 8235 O O   . LYS E 5 374 ? 99.106  82.737  123.572 1.00 75.75  ? 321 LYS R O   1 
ATOM 8236 C CB  . LYS E 5 374 ? 98.246  79.694  122.659 1.00 73.83  ? 321 LYS R CB  1 
ATOM 8237 C CG  . LYS E 5 374 ? 99.318  79.423  123.694 1.00 73.42  ? 321 LYS R CG  1 
ATOM 8238 C CD  . LYS E 5 374 ? 99.902  78.031  123.519 1.00 75.15  ? 321 LYS R CD  1 
ATOM 8239 C CE  . LYS E 5 374 ? 100.972 77.743  124.559 1.00 76.87  ? 321 LYS R CE  1 
ATOM 8240 N NZ  . LYS E 5 374 ? 101.545 76.378  124.400 1.00 74.85  ? 321 LYS R NZ  1 
ATOM 8241 N N   . ARG E 5 375 ? 98.925  82.519  121.341 1.00 70.06  ? 322 ARG R N   1 
ATOM 8242 C CA  . ARG E 5 375 ? 99.928  83.550  121.095 1.00 74.56  ? 322 ARG R CA  1 
ATOM 8243 C C   . ARG E 5 375 ? 99.390  84.942  121.399 1.00 74.35  ? 322 ARG R C   1 
ATOM 8244 O O   . ARG E 5 375 ? 100.104 85.778  121.965 1.00 76.74  ? 322 ARG R O   1 
ATOM 8245 C CB  . ARG E 5 375 ? 100.431 83.475  119.656 1.00 71.14  ? 322 ARG R CB  1 
ATOM 8246 C CG  . ARG E 5 375 ? 101.370 82.318  119.398 1.00 76.09  ? 322 ARG R CG  1 
ATOM 8247 C CD  . ARG E 5 375 ? 101.975 82.405  118.012 1.00 79.79  ? 322 ARG R CD  1 
ATOM 8248 N NE  . ARG E 5 375 ? 102.994 81.385  117.802 1.00 80.65  ? 322 ARG R NE  1 
ATOM 8249 C CZ  . ARG E 5 375 ? 103.707 81.258  116.692 1.00 80.51  ? 322 ARG R CZ  1 
ATOM 8250 N NH1 . ARG E 5 375 ? 103.535 82.072  115.664 1.00 78.68  ? 322 ARG R NH1 1 
ATOM 8251 N NH2 . ARG E 5 375 ? 104.615 80.289  116.611 1.00 78.03  ? 322 ARG R NH2 1 
ATOM 8252 N N   . VAL E 5 376 ? 98.141  85.217  121.025 1.00 64.39  ? 323 VAL R N   1 
ATOM 8253 C CA  . VAL E 5 376 ? 97.563  86.527  121.302 1.00 63.07  ? 323 VAL R CA  1 
ATOM 8254 C C   . VAL E 5 376 ? 97.388  86.726  122.801 1.00 67.99  ? 323 VAL R C   1 
ATOM 8255 O O   . VAL E 5 376 ? 97.552  87.838  123.315 1.00 77.07  ? 323 VAL R O   1 
ATOM 8256 C CB  . VAL E 5 376 ? 96.236  86.696  120.542 1.00 62.70  ? 323 VAL R CB  1 
ATOM 8257 C CG1 . VAL E 5 376 ? 95.550  87.991  120.936 1.00 58.94  ? 323 VAL R CG1 1 
ATOM 8258 C CG2 . VAL E 5 376 ? 96.484  86.669  119.046 1.00 68.60  ? 323 VAL R CG2 1 
ATOM 8259 N N   . THR E 5 377 ? 97.051  85.658  123.526 1.00 70.55  ? 324 THR R N   1 
ATOM 8260 C CA  . THR E 5 377 ? 96.860  85.777  124.968 1.00 69.03  ? 324 THR R CA  1 
ATOM 8261 C C   . THR E 5 377 ? 98.153  86.185  125.664 1.00 65.29  ? 324 THR R C   1 
ATOM 8262 O O   . THR E 5 377 ? 98.154  87.078  126.517 1.00 70.92  ? 324 THR R O   1 
ATOM 8263 C CB  . THR E 5 377 ? 96.331  84.464  125.545 1.00 70.18  ? 324 THR R CB  1 
ATOM 8264 O OG1 . THR E 5 377 ? 95.054  84.168  124.968 1.00 73.66  ? 324 THR R OG1 1 
ATOM 8265 C CG2 . THR E 5 377 ? 96.181  84.569  127.051 1.00 67.27  ? 324 THR R CG2 1 
ATOM 8266 N N   . ARG E 5 378 ? 99.272  85.555  125.302 1.00 65.00  ? 325 ARG R N   1 
ATOM 8267 C CA  . ARG E 5 378 ? 100.532 85.905  125.946 1.00 71.85  ? 325 ARG R CA  1 
ATOM 8268 C C   . ARG E 5 378 ? 101.081 87.243  125.470 1.00 73.68  ? 325 ARG R C   1 
ATOM 8269 O O   . ARG E 5 378 ? 101.951 87.811  126.136 1.00 76.93  ? 325 ARG R O   1 
ATOM 8270 C CB  . ARG E 5 378 ? 101.574 84.806  125.730 1.00 71.74  ? 325 ARG R CB  1 
ATOM 8271 C CG  . ARG E 5 378 ? 102.211 84.779  124.357 1.00 70.27  ? 325 ARG R CG  1 
ATOM 8272 C CD  . ARG E 5 378 ? 103.491 83.963  124.394 1.00 72.47  ? 325 ARG R CD  1 
ATOM 8273 N NE  . ARG E 5 378 ? 104.148 83.899  123.095 1.00 78.28  ? 325 ARG R NE  1 
ATOM 8274 C CZ  . ARG E 5 378 ? 104.109 82.849  122.288 1.00 79.82  ? 325 ARG R CZ  1 
ATOM 8275 N NH1 . ARG E 5 378 ? 103.463 81.744  122.622 1.00 75.30  ? 325 ARG R NH1 1 
ATOM 8276 N NH2 . ARG E 5 378 ? 104.741 82.905  121.119 1.00 76.55  ? 325 ARG R NH2 1 
ATOM 8277 N N   . THR E 5 379 ? 100.601 87.761  124.339 1.00 69.05  ? 326 THR R N   1 
ATOM 8278 C CA  . THR E 5 379 ? 100.985 89.108  123.932 1.00 64.90  ? 326 THR R CA  1 
ATOM 8279 C C   . THR E 5 379 ? 100.137 90.154  124.642 1.00 60.45  ? 326 THR R C   1 
ATOM 8280 O O   . THR E 5 379 ? 100.647 91.205  125.041 1.00 64.71  ? 326 THR R O   1 
ATOM 8281 C CB  . THR E 5 379 ? 100.868 89.263  122.416 1.00 65.41  ? 326 THR R CB  1 
ATOM 8282 O OG1 . THR E 5 379 ? 101.644 88.248  121.771 1.00 71.59  ? 326 THR R OG1 1 
ATOM 8283 C CG2 . THR E 5 379 ? 101.381 90.624  121.980 1.00 63.42  ? 326 THR R CG2 1 
ATOM 8284 N N   . ALA E 5 380 ? 98.844  89.882  124.814 1.00 61.21  ? 327 ALA R N   1 
ATOM 8285 C CA  . ALA E 5 380 ? 97.991  90.808  125.547 1.00 64.93  ? 327 ALA R CA  1 
ATOM 8286 C C   . ALA E 5 380 ? 98.332  90.828  127.029 1.00 69.57  ? 327 ALA R C   1 
ATOM 8287 O O   . ALA E 5 380 ? 98.230  91.879  127.672 1.00 70.47  ? 327 ALA R O   1 
ATOM 8288 C CB  . ALA E 5 380 ? 96.521  90.443  125.347 1.00 64.93  ? 327 ALA R CB  1 
ATOM 8289 N N   . ILE E 5 381 ? 98.724  89.683  127.591 1.00 73.77  ? 328 ILE R N   1 
ATOM 8290 C CA  . ILE E 5 381 ? 99.105  89.638  128.999 1.00 70.25  ? 328 ILE R CA  1 
ATOM 8291 C C   . ILE E 5 381 ? 100.378 90.440  129.235 1.00 70.42  ? 328 ILE R C   1 
ATOM 8292 O O   . ILE E 5 381 ? 100.466 91.219  130.189 1.00 76.10  ? 328 ILE R O   1 
ATOM 8293 C CB  . ILE E 5 381 ? 99.260  88.180  129.466 1.00 70.11  ? 328 ILE R CB  1 
ATOM 8294 C CG1 . ILE E 5 381 ? 97.889  87.527  129.640 1.00 75.71  ? 328 ILE R CG1 1 
ATOM 8295 C CG2 . ILE E 5 381 ? 100.054 88.108  130.759 1.00 67.39  ? 328 ILE R CG2 1 
ATOM 8296 C CD1 . ILE E 5 381 ? 97.956  86.083  130.070 1.00 71.73  ? 328 ILE R CD1 1 
ATOM 8297 N N   . ALA E 5 382 ? 101.378 90.273  128.366 1.00 69.24  ? 329 ALA R N   1 
ATOM 8298 C CA  . ALA E 5 382 ? 102.649 90.960  128.567 1.00 65.05  ? 329 ALA R CA  1 
ATOM 8299 C C   . ALA E 5 382 ? 102.483 92.473  128.507 1.00 70.83  ? 329 ALA R C   1 
ATOM 8300 O O   . ALA E 5 382 ? 103.061 93.197  129.325 1.00 78.30  ? 329 ALA R O   1 
ATOM 8301 C CB  . ALA E 5 382 ? 103.668 90.496  127.529 1.00 63.15  ? 329 ALA R CB  1 
ATOM 8302 N N   . ILE E 5 383 ? 101.692 92.970  127.555 1.00 68.51  ? 330 ILE R N   1 
ATOM 8303 C CA  . ILE E 5 383 ? 101.512 94.413  127.422 1.00 63.37  ? 330 ILE R CA  1 
ATOM 8304 C C   . ILE E 5 383 ? 100.849 94.987  128.667 1.00 64.56  ? 330 ILE R C   1 
ATOM 8305 O O   . ILE E 5 383 ? 101.243 96.047  129.166 1.00 68.88  ? 330 ILE R O   1 
ATOM 8306 C CB  . ILE E 5 383 ? 100.714 94.735  126.147 1.00 64.99  ? 330 ILE R CB  1 
ATOM 8307 C CG1 . ILE E 5 383 ? 101.506 94.302  124.915 1.00 65.01  ? 330 ILE R CG1 1 
ATOM 8308 C CG2 . ILE E 5 383 ? 100.402 96.213  126.072 1.00 66.65  ? 330 ILE R CG2 1 
ATOM 8309 C CD1 . ILE E 5 383 ? 100.758 94.473  123.624 1.00 64.89  ? 330 ILE R CD1 1 
ATOM 8310 N N   . CYS E 5 384 ? 99.831  94.302  129.189 1.00 67.29  ? 331 CYS R N   1 
ATOM 8311 C CA  . CYS E 5 384 ? 99.194  94.765  130.416 1.00 68.32  ? 331 CYS R CA  1 
ATOM 8312 C C   . CYS E 5 384 ? 100.088 94.548  131.630 1.00 69.24  ? 331 CYS R C   1 
ATOM 8313 O O   . CYS E 5 384 ? 100.070 95.358  132.562 1.00 74.22  ? 331 CYS R O   1 
ATOM 8314 C CB  . CYS E 5 384 ? 97.852  94.061  130.616 1.00 70.31  ? 331 CYS R CB  1 
ATOM 8315 S SG  . CYS E 5 384 ? 96.653  94.350  129.302 1.00 79.80  ? 331 CYS R SG  1 
ATOM 8316 N N   . LEU E 5 385 ? 100.864 93.461  131.643 1.00 75.73  ? 332 LEU R N   1 
ATOM 8317 C CA  . LEU E 5 385 ? 101.722 93.176  132.789 1.00 76.15  ? 332 LEU R CA  1 
ATOM 8318 C C   . LEU E 5 385 ? 102.936 94.095  132.822 1.00 77.45  ? 332 LEU R C   1 
ATOM 8319 O O   . LEU E 5 385 ? 103.324 94.577  133.891 1.00 82.36  ? 332 LEU R O   1 
ATOM 8320 C CB  . LEU E 5 385 ? 102.160 91.713  132.769 1.00 76.25  ? 332 LEU R CB  1 
ATOM 8321 C CG  . LEU E 5 385 ? 102.917 91.212  133.997 1.00 77.21  ? 332 LEU R CG  1 
ATOM 8322 C CD1 . LEU E 5 385 ? 102.055 91.344  135.240 1.00 76.49  ? 332 LEU R CD1 1 
ATOM 8323 C CD2 . LEU E 5 385 ? 103.358 89.774  133.799 1.00 78.43  ? 332 LEU R CD2 1 
ATOM 8324 N N   . VAL E 5 386 ? 103.554 94.345  131.665 1.00 71.04  ? 333 VAL R N   1 
ATOM 8325 C CA  . VAL E 5 386 ? 104.733 95.207  131.626 1.00 70.15  ? 333 VAL R CA  1 
ATOM 8326 C C   . VAL E 5 386 ? 104.380 96.616  132.080 1.00 76.07  ? 333 VAL R C   1 
ATOM 8327 O O   . VAL E 5 386 ? 105.115 97.236  132.857 1.00 83.13  ? 333 VAL R O   1 
ATOM 8328 C CB  . VAL E 5 386 ? 105.358 95.204  130.219 1.00 73.47  ? 333 VAL R CB  1 
ATOM 8329 C CG1 . VAL E 5 386 ? 106.317 96.369  130.057 1.00 72.06  ? 333 VAL R CG1 1 
ATOM 8330 C CG2 . VAL E 5 386 ? 106.081 93.895  129.971 1.00 76.39  ? 333 VAL R CG2 1 
ATOM 8331 N N   . PHE E 5 387 ? 103.247 97.141  131.612 1.00 76.94  ? 334 PHE R N   1 
ATOM 8332 C CA  . PHE E 5 387 ? 102.835 98.476  132.029 1.00 77.52  ? 334 PHE R CA  1 
ATOM 8333 C C   . PHE E 5 387 ? 102.570 98.533  133.528 1.00 77.56  ? 334 PHE R C   1 
ATOM 8334 O O   . PHE E 5 387 ? 102.950 99.501  134.194 1.00 85.42  ? 334 PHE R O   1 
ATOM 8335 C CB  . PHE E 5 387 ? 101.595 98.913  131.251 1.00 74.84  ? 334 PHE R CB  1 
ATOM 8336 C CG  . PHE E 5 387 ? 101.144 100.305 131.571 1.00 74.86  ? 334 PHE R CG  1 
ATOM 8337 C CD1 . PHE E 5 387 ? 101.719 101.392 130.939 1.00 77.75  ? 334 PHE R CD1 1 
ATOM 8338 C CD2 . PHE E 5 387 ? 100.153 100.530 132.506 1.00 74.56  ? 334 PHE R CD2 1 
ATOM 8339 C CE1 . PHE E 5 387 ? 101.312 102.673 131.231 1.00 75.97  ? 334 PHE R CE1 1 
ATOM 8340 C CE2 . PHE E 5 387 ? 99.742  101.810 132.802 1.00 78.03  ? 334 PHE R CE2 1 
ATOM 8341 C CZ  . PHE E 5 387 ? 100.322 102.883 132.163 1.00 78.51  ? 334 PHE R CZ  1 
ATOM 8342 N N   . PHE E 5 388 ? 101.914 97.510  134.077 1.00 75.43  ? 335 PHE R N   1 
ATOM 8343 C CA  . PHE E 5 388 ? 101.604 97.520  135.502 1.00 76.87  ? 335 PHE R CA  1 
ATOM 8344 C C   . PHE E 5 388 ? 102.862 97.356  136.345 1.00 83.15  ? 335 PHE R C   1 
ATOM 8345 O O   . PHE E 5 388 ? 103.078 98.102  137.304 1.00 85.01  ? 335 PHE R O   1 
ATOM 8346 C CB  . PHE E 5 388 ? 100.592 96.423  135.830 1.00 78.60  ? 335 PHE R CB  1 
ATOM 8347 C CG  . PHE E 5 388 ? 100.179 96.396  137.272 1.00 82.11  ? 335 PHE R CG  1 
ATOM 8348 C CD1 . PHE E 5 388 ? 99.192  97.245  137.737 1.00 81.82  ? 335 PHE R CD1 1 
ATOM 8349 C CD2 . PHE E 5 388 ? 100.779 95.522  138.162 1.00 80.38  ? 335 PHE R CD2 1 
ATOM 8350 C CE1 . PHE E 5 388 ? 98.810  97.223  139.062 1.00 82.67  ? 335 PHE R CE1 1 
ATOM 8351 C CE2 . PHE E 5 388 ? 100.401 95.497  139.488 1.00 80.73  ? 335 PHE R CE2 1 
ATOM 8352 C CZ  . PHE E 5 388 ? 99.415  96.348  139.938 1.00 82.28  ? 335 PHE R CZ  1 
ATOM 8353 N N   . VAL E 5 389 ? 103.709 96.386  135.996 1.00 89.17  ? 336 VAL R N   1 
ATOM 8354 C CA  . VAL E 5 389 ? 104.899 96.113  136.799 1.00 83.46  ? 336 VAL R CA  1 
ATOM 8355 C C   . VAL E 5 389 ? 105.842 97.308  136.790 1.00 85.68  ? 336 VAL R C   1 
ATOM 8356 O O   . VAL E 5 389 ? 106.398 97.686  137.828 1.00 92.78  ? 336 VAL R O   1 
ATOM 8357 C CB  . VAL E 5 389 ? 105.600 94.836  136.300 1.00 83.16  ? 336 VAL R CB  1 
ATOM 8358 C CG1 . VAL E 5 389 ? 106.974 94.705  136.926 1.00 80.89  ? 336 VAL R CG1 1 
ATOM 8359 C CG2 . VAL E 5 389 ? 104.761 93.614  136.626 1.00 86.66  ? 336 VAL R CG2 1 
ATOM 8360 N N   . CYS E 5 390 ? 106.031 97.928  135.627 1.00 91.53  ? 337 CYS R N   1 
ATOM 8361 C CA  . CYS E 5 390 ? 107.016 98.993  135.503 1.00 93.78  ? 337 CYS R CA  1 
ATOM 8362 C C   . CYS E 5 390 ? 106.566 100.315 136.110 1.00 97.28  ? 337 CYS R C   1 
ATOM 8363 O O   . CYS E 5 390 ? 107.410 101.189 136.333 1.00 101.13 ? 337 CYS R O   1 
ATOM 8364 C CB  . CYS E 5 390 ? 107.371 99.208  134.031 1.00 93.12  ? 337 CYS R CB  1 
ATOM 8365 S SG  . CYS E 5 390 ? 108.221 97.815  133.259 1.00 103.63 ? 337 CYS R SG  1 
ATOM 8366 N N   . TRP E 5 391 ? 105.273 100.491 136.389 1.00 93.58  ? 338 TRP R N   1 
ATOM 8367 C CA  . TRP E 5 391 ? 104.776 101.769 136.879 1.00 92.84  ? 338 TRP R CA  1 
ATOM 8368 C C   . TRP E 5 391 ? 104.039 101.714 138.208 1.00 95.33  ? 338 TRP R C   1 
ATOM 8369 O O   . TRP E 5 391 ? 103.931 102.754 138.864 1.00 100.94 ? 338 TRP R O   1 
ATOM 8370 C CB  . TRP E 5 391 ? 103.849 102.421 135.842 1.00 92.99  ? 338 TRP R CB  1 
ATOM 8371 C CG  . TRP E 5 391 ? 104.582 103.089 134.727 1.00 94.70  ? 338 TRP R CG  1 
ATOM 8372 C CD1 . TRP E 5 391 ? 104.636 102.691 133.426 1.00 94.77  ? 338 TRP R CD1 1 
ATOM 8373 C CD2 . TRP E 5 391 ? 105.374 104.277 134.817 1.00 97.91  ? 338 TRP R CD2 1 
ATOM 8374 N NE1 . TRP E 5 391 ? 105.410 103.560 132.697 1.00 94.94  ? 338 TRP R NE1 1 
ATOM 8375 C CE2 . TRP E 5 391 ? 105.876 104.542 133.530 1.00 95.72  ? 338 TRP R CE2 1 
ATOM 8376 C CE3 . TRP E 5 391 ? 105.708 105.142 135.863 1.00 97.07  ? 338 TRP R CE3 1 
ATOM 8377 C CZ2 . TRP E 5 391 ? 106.694 105.635 133.260 1.00 95.69  ? 338 TRP R CZ2 1 
ATOM 8378 C CZ3 . TRP E 5 391 ? 106.518 106.225 135.594 1.00 94.45  ? 338 TRP R CZ3 1 
ATOM 8379 C CH2 . TRP E 5 391 ? 107.002 106.463 134.303 1.00 97.01  ? 338 TRP R CH2 1 
ATOM 8380 N N   . ALA E 5 392 ? 103.521 100.557 138.620 1.00 101.29 ? 339 ALA R N   1 
ATOM 8381 C CA  . ALA E 5 392 ? 102.788 100.494 139.884 1.00 102.30 ? 339 ALA R CA  1 
ATOM 8382 C C   . ALA E 5 392 ? 103.636 100.873 141.092 1.00 104.91 ? 339 ALA R C   1 
ATOM 8383 O O   . ALA E 5 392 ? 103.162 101.674 141.917 1.00 108.11 ? 339 ALA R O   1 
ATOM 8384 C CB  . ALA E 5 392 ? 102.166 99.107  140.063 1.00 102.69 ? 339 ALA R CB  1 
ATOM 8385 N N   . PRO E 5 393 ? 104.856 100.353 141.280 1.00 106.49 ? 340 PRO R N   1 
ATOM 8386 C CA  . PRO E 5 393 ? 105.619 100.735 142.481 1.00 107.35 ? 340 PRO R CA  1 
ATOM 8387 C C   . PRO E 5 393 ? 105.897 102.224 142.584 1.00 106.56 ? 340 PRO R C   1 
ATOM 8388 O O   . PRO E 5 393 ? 105.959 102.754 143.699 1.00 107.60 ? 340 PRO R O   1 
ATOM 8389 C CB  . PRO E 5 393 ? 106.916 99.923  142.347 1.00 108.58 ? 340 PRO R CB  1 
ATOM 8390 C CG  . PRO E 5 393 ? 107.012 99.590  140.906 1.00 106.16 ? 340 PRO R CG  1 
ATOM 8391 C CD  . PRO E 5 393 ? 105.604 99.382  140.462 1.00 104.52 ? 340 PRO R CD  1 
ATOM 8392 N N   . TYR E 5 394 ? 106.068 102.916 141.455 1.00 109.90 ? 341 TYR R N   1 
ATOM 8393 C CA  . TYR E 5 394 ? 106.335 104.350 141.503 1.00 108.83 ? 341 TYR R CA  1 
ATOM 8394 C C   . TYR E 5 394 ? 105.168 105.115 142.111 1.00 111.01 ? 341 TYR R C   1 
ATOM 8395 O O   . TYR E 5 394 ? 105.367 106.025 142.923 1.00 114.14 ? 341 TYR R O   1 
ATOM 8396 C CB  . TYR E 5 394 ? 106.642 104.879 140.103 1.00 108.94 ? 341 TYR R CB  1 
ATOM 8397 C CG  . TYR E 5 394 ? 106.897 106.369 140.066 1.00 110.38 ? 341 TYR R CG  1 
ATOM 8398 C CD1 . TYR E 5 394 ? 108.143 106.887 140.386 1.00 112.56 ? 341 TYR R CD1 1 
ATOM 8399 C CD2 . TYR E 5 394 ? 105.889 107.258 139.716 1.00 110.19 ? 341 TYR R CD2 1 
ATOM 8400 C CE1 . TYR E 5 394 ? 108.380 108.247 140.356 1.00 112.16 ? 341 TYR R CE1 1 
ATOM 8401 C CE2 . TYR E 5 394 ? 106.116 108.619 139.685 1.00 109.96 ? 341 TYR R CE2 1 
ATOM 8402 C CZ  . TYR E 5 394 ? 107.363 109.108 140.005 1.00 110.11 ? 341 TYR R CZ  1 
ATOM 8403 O OH  . TYR E 5 394 ? 107.596 110.463 139.974 1.00 108.96 ? 341 TYR R OH  1 
ATOM 8404 N N   . TYR E 5 395 ? 103.942 104.762 141.731 1.00 108.55 ? 342 TYR R N   1 
ATOM 8405 C CA  . TYR E 5 395 ? 102.773 105.468 142.236 1.00 104.96 ? 342 TYR R CA  1 
ATOM 8406 C C   . TYR E 5 395 ? 102.299 104.944 143.582 1.00 108.40 ? 342 TYR R C   1 
ATOM 8407 O O   . TYR E 5 395 ? 101.647 105.689 144.321 1.00 110.82 ? 342 TYR R O   1 
ATOM 8408 C CB  . TYR E 5 395 ? 101.642 105.392 141.215 1.00 102.38 ? 342 TYR R CB  1 
ATOM 8409 C CG  . TYR E 5 395 ? 101.911 106.218 139.983 1.00 105.61 ? 342 TYR R CG  1 
ATOM 8410 C CD1 . TYR E 5 395 ? 101.615 107.571 139.958 1.00 107.30 ? 342 TYR R CD1 1 
ATOM 8411 C CD2 . TYR E 5 395 ? 102.477 105.650 138.851 1.00 105.94 ? 342 TYR R CD2 1 
ATOM 8412 C CE1 . TYR E 5 395 ? 101.864 108.334 138.838 1.00 107.08 ? 342 TYR R CE1 1 
ATOM 8413 C CE2 . TYR E 5 395 ? 102.729 106.406 137.726 1.00 106.12 ? 342 TYR R CE2 1 
ATOM 8414 C CZ  . TYR E 5 395 ? 102.421 107.747 137.726 1.00 105.80 ? 342 TYR R CZ  1 
ATOM 8415 O OH  . TYR E 5 395 ? 102.668 108.510 136.611 1.00 106.10 ? 342 TYR R OH  1 
ATOM 8416 N N   . VAL E 5 396 ? 102.601 103.690 143.918 1.00 120.16 ? 343 VAL R N   1 
ATOM 8417 C CA  . VAL E 5 396 ? 102.297 103.197 145.258 1.00 120.06 ? 343 VAL R CA  1 
ATOM 8418 C C   . VAL E 5 396 ? 103.107 103.962 146.296 1.00 121.30 ? 343 VAL R C   1 
ATOM 8419 O O   . VAL E 5 396 ? 102.582 104.369 147.340 1.00 121.63 ? 343 VAL R O   1 
ATOM 8420 C CB  . VAL E 5 396 ? 102.546 101.680 145.342 1.00 119.24 ? 343 VAL R CB  1 
ATOM 8421 C CG1 . VAL E 5 396 ? 102.552 101.220 146.790 1.00 119.21 ? 343 VAL R CG1 1 
ATOM 8422 C CG2 . VAL E 5 396 ? 101.488 100.929 144.553 1.00 118.84 ? 343 VAL R CG2 1 
ATOM 8423 N N   . LEU E 5 397 ? 104.396 104.180 146.024 1.00 127.42 ? 344 LEU R N   1 
ATOM 8424 C CA  . LEU E 5 397 ? 105.200 105.023 146.902 1.00 127.54 ? 344 LEU R CA  1 
ATOM 8425 C C   . LEU E 5 397 ? 104.771 106.481 146.827 1.00 126.85 ? 344 LEU R C   1 
ATOM 8426 O O   . LEU E 5 397 ? 104.831 107.195 147.834 1.00 129.99 ? 344 LEU R O   1 
ATOM 8427 C CB  . LEU E 5 397 ? 106.681 104.890 146.553 1.00 126.74 ? 344 LEU R CB  1 
ATOM 8428 C CG  . LEU E 5 397 ? 107.282 103.493 146.699 1.00 127.82 ? 344 LEU R CG  1 
ATOM 8429 C CD1 . LEU E 5 397 ? 108.744 103.496 146.288 1.00 127.27 ? 344 LEU R CD1 1 
ATOM 8430 C CD2 . LEU E 5 397 ? 107.123 102.991 148.125 1.00 127.18 ? 344 LEU R CD2 1 
ATOM 8431 N N   . GLN E 5 398 ? 104.345 106.941 145.649 1.00 124.29 ? 345 GLN R N   1 
ATOM 8432 C CA  . GLN E 5 398 ? 103.855 108.310 145.525 1.00 125.50 ? 345 GLN R CA  1 
ATOM 8433 C C   . GLN E 5 398 ? 102.604 108.521 146.367 1.00 126.42 ? 345 GLN R C   1 
ATOM 8434 O O   . GLN E 5 398 ? 102.434 109.575 146.990 1.00 127.32 ? 345 GLN R O   1 
ATOM 8435 C CB  . GLN E 5 398 ? 103.578 108.636 144.057 1.00 127.08 ? 345 GLN R CB  1 
ATOM 8436 C CG  . GLN E 5 398 ? 103.883 110.071 143.661 1.00 126.73 ? 345 GLN R CG  1 
ATOM 8437 C CD  . GLN E 5 398 ? 105.371 110.334 143.526 1.00 128.10 ? 345 GLN R CD  1 
ATOM 8438 O OE1 . GLN E 5 398 ? 105.819 111.477 143.603 1.00 128.27 ? 345 GLN R OE1 1 
ATOM 8439 N NE2 . GLN E 5 398 ? 106.143 109.274 143.315 1.00 126.98 ? 345 GLN R NE2 1 
ATOM 8440 N N   . LEU E 5 399 ? 101.707 107.533 146.387 1.00 129.96 ? 346 LEU R N   1 
ATOM 8441 C CA  . LEU E 5 399 ? 100.552 107.598 147.275 1.00 131.12 ? 346 LEU R CA  1 
ATOM 8442 C C   . LEU E 5 399 ? 100.940 107.373 148.731 1.00 131.64 ? 346 LEU R C   1 
ATOM 8443 O O   . LEU E 5 399 ? 100.322 107.953 149.630 1.00 130.89 ? 346 LEU R O   1 
ATOM 8444 C CB  . LEU E 5 399 ? 99.500  106.576 146.846 1.00 129.66 ? 346 LEU R CB  1 
ATOM 8445 C CG  . LEU E 5 399 ? 98.865  106.792 145.473 1.00 129.32 ? 346 LEU R CG  1 
ATOM 8446 C CD1 . LEU E 5 399 ? 97.842  105.708 145.183 1.00 128.79 ? 346 LEU R CD1 1 
ATOM 8447 C CD2 . LEU E 5 399 ? 98.228  108.166 145.395 1.00 130.54 ? 346 LEU R CD2 1 
ATOM 8448 N N   . THR E 5 400 ? 101.949 106.536 148.984 1.00 138.07 ? 347 THR R N   1 
ATOM 8449 C CA  . THR E 5 400 ? 102.375 106.284 150.358 1.00 138.36 ? 347 THR R CA  1 
ATOM 8450 C C   . THR E 5 400 ? 102.972 107.533 150.997 1.00 139.03 ? 347 THR R C   1 
ATOM 8451 O O   . THR E 5 400 ? 102.752 107.792 152.186 1.00 139.62 ? 347 THR R O   1 
ATOM 8452 C CB  . THR E 5 400 ? 103.379 105.132 150.393 1.00 138.19 ? 347 THR R CB  1 
ATOM 8453 O OG1 . THR E 5 400 ? 102.811 103.983 149.753 1.00 136.44 ? 347 THR R OG1 1 
ATOM 8454 C CG2 . THR E 5 400 ? 103.738 104.776 151.827 1.00 137.29 ? 347 THR R CG2 1 
ATOM 8455 N N   . GLN E 5 401 ? 103.722 108.324 150.227 1.00 139.32 ? 348 GLN R N   1 
ATOM 8456 C CA  . GLN E 5 401 ? 104.360 109.511 150.783 1.00 138.82 ? 348 GLN R CA  1 
ATOM 8457 C C   . GLN E 5 401 ? 103.358 110.588 151.181 1.00 140.39 ? 348 GLN R C   1 
ATOM 8458 O O   . GLN E 5 401 ? 103.747 111.550 151.851 1.00 139.20 ? 348 GLN R O   1 
ATOM 8459 C CB  . GLN E 5 401 ? 105.372 110.091 149.794 1.00 138.73 ? 348 GLN R CB  1 
ATOM 8460 C CG  . GLN E 5 401 ? 104.759 110.922 148.684 1.00 139.42 ? 348 GLN R CG  1 
ATOM 8461 C CD  . GLN E 5 401 ? 105.804 111.543 147.779 1.00 139.57 ? 348 GLN R CD  1 
ATOM 8462 O OE1 . GLN E 5 401 ? 106.991 111.229 147.875 1.00 139.38 ? 348 GLN R OE1 1 
ATOM 8463 N NE2 . GLN E 5 401 ? 105.369 112.435 146.897 1.00 139.45 ? 348 GLN R NE2 1 
ATOM 8464 N N   . LEU E 5 402 ? 102.093 110.464 150.773 1.00 148.39 ? 349 LEU R N   1 
ATOM 8465 C CA  . LEU E 5 402 ? 101.076 111.401 151.239 1.00 148.79 ? 349 LEU R CA  1 
ATOM 8466 C C   . LEU E 5 402 ? 100.900 111.312 152.749 1.00 149.37 ? 349 LEU R C   1 
ATOM 8467 O O   . LEU E 5 402 ? 100.824 112.337 153.436 1.00 148.26 ? 349 LEU R O   1 
ATOM 8468 C CB  . LEU E 5 402 ? 99.750  111.133 150.526 1.00 147.46 ? 349 LEU R CB  1 
ATOM 8469 C CG  . LEU E 5 402 ? 99.765  111.270 149.004 1.00 147.44 ? 349 LEU R CG  1 
ATOM 8470 C CD1 . LEU E 5 402 ? 98.401  110.933 148.424 1.00 147.46 ? 349 LEU R CD1 1 
ATOM 8471 C CD2 . LEU E 5 402 ? 100.191 112.670 148.597 1.00 147.50 ? 349 LEU R CD2 1 
ATOM 8472 N N   . SER E 5 403 ? 100.833 110.092 153.285 1.00 155.54 ? 350 SER R N   1 
ATOM 8473 C CA  . SER E 5 403 ? 100.761 109.911 154.730 1.00 155.34 ? 350 SER R CA  1 
ATOM 8474 C C   . SER E 5 403 ? 102.127 110.048 155.390 1.00 155.36 ? 350 SER R C   1 
ATOM 8475 O O   . SER E 5 403 ? 102.216 110.519 156.529 1.00 154.40 ? 350 SER R O   1 
ATOM 8476 C CB  . SER E 5 403 ? 100.152 108.548 155.061 1.00 154.13 ? 350 SER R CB  1 
ATOM 8477 O OG  . SER E 5 403 ? 100.928 107.496 154.514 1.00 154.37 ? 350 SER R OG  1 
ATOM 8478 N N   . ILE E 5 404 ? 103.192 109.645 154.697 1.00 155.39 ? 351 ILE R N   1 
ATOM 8479 C CA  . ILE E 5 404 ? 104.531 109.687 155.271 1.00 155.42 ? 351 ILE R CA  1 
ATOM 8480 C C   . ILE E 5 404 ? 105.027 111.126 155.301 1.00 155.70 ? 351 ILE R C   1 
ATOM 8481 O O   . ILE E 5 404 ? 104.969 111.843 154.293 1.00 154.71 ? 351 ILE R O   1 
ATOM 8482 C CB  . ILE E 5 404 ? 105.486 108.785 154.476 1.00 154.58 ? 351 ILE R CB  1 
ATOM 8483 C CG1 . ILE E 5 404 ? 105.010 107.331 154.527 1.00 154.33 ? 351 ILE R CG1 1 
ATOM 8484 C CG2 . ILE E 5 404 ? 106.904 108.901 155.013 1.00 154.13 ? 351 ILE R CG2 1 
ATOM 8485 C CD1 . ILE E 5 404 ? 104.961 106.753 155.924 1.00 153.65 ? 351 ILE R CD1 1 
ATOM 8486 N N   . SER E 5 405 ? 105.519 111.556 156.461 1.00 161.20 ? 352 SER R N   1 
ATOM 8487 C CA  . SER E 5 405 ? 106.055 112.901 156.635 1.00 160.58 ? 352 SER R CA  1 
ATOM 8488 C C   . SER E 5 405 ? 107.577 112.938 156.567 1.00 161.02 ? 352 SER R C   1 
ATOM 8489 O O   . SER E 5 405 ? 108.146 113.809 155.904 1.00 160.06 ? 352 SER R O   1 
ATOM 8490 C CB  . SER E 5 405 ? 105.577 113.488 157.969 1.00 159.64 ? 352 SER R CB  1 
ATOM 8491 O OG  . SER E 5 405 ? 104.163 113.565 158.014 1.00 159.08 ? 352 SER R OG  1 
ATOM 8492 N N   . ARG E 5 406 ? 108.248 112.007 157.241 1.00 169.51 ? 353 ARG R N   1 
ATOM 8493 C CA  . ARG E 5 406 ? 109.709 111.932 157.236 1.00 169.64 ? 353 ARG R CA  1 
ATOM 8494 C C   . ARG E 5 406 ? 110.148 110.622 156.598 1.00 170.40 ? 353 ARG R C   1 
ATOM 8495 O O   . ARG E 5 406 ? 110.091 109.562 157.248 1.00 168.75 ? 353 ARG R O   1 
ATOM 8496 C CB  . ARG E 5 406 ? 110.264 112.051 158.654 1.00 168.25 ? 353 ARG R CB  1 
ATOM 8497 N N   . PRO E 5 407 ? 110.582 110.636 155.340 1.00 170.55 ? 354 PRO R N   1 
ATOM 8498 C CA  . PRO E 5 407 ? 111.023 109.393 154.699 1.00 169.88 ? 354 PRO R CA  1 
ATOM 8499 C C   . PRO E 5 407 ? 112.284 108.843 155.345 1.00 169.32 ? 354 PRO R C   1 
ATOM 8500 O O   . PRO E 5 407 ? 113.123 109.583 155.864 1.00 168.57 ? 354 PRO R O   1 
ATOM 8501 C CB  . PRO E 5 407 ? 111.280 109.814 153.248 1.00 168.69 ? 354 PRO R CB  1 
ATOM 8502 C CG  . PRO E 5 407 ? 111.573 111.276 153.331 1.00 167.77 ? 354 PRO R CG  1 
ATOM 8503 C CD  . PRO E 5 407 ? 110.711 111.799 154.446 1.00 167.75 ? 354 PRO R CD  1 
ATOM 8504 N N   . THR E 5 408 ? 112.409 107.520 155.304 1.00 172.43 ? 355 THR R N   1 
ATOM 8505 C CA  . THR E 5 408 ? 113.557 106.821 155.856 1.00 173.21 ? 355 THR R CA  1 
ATOM 8506 C C   . THR E 5 408 ? 114.492 106.378 154.732 1.00 172.78 ? 355 THR R C   1 
ATOM 8507 O O   . THR E 5 408 ? 114.211 106.555 153.544 1.00 171.54 ? 355 THR R O   1 
ATOM 8508 C CB  . THR E 5 408 ? 113.104 105.627 156.698 1.00 172.44 ? 355 THR R CB  1 
ATOM 8509 O OG1 . THR E 5 408 ? 114.249 104.885 157.137 1.00 171.98 ? 355 THR R OG1 1 
ATOM 8510 C CG2 . THR E 5 408 ? 112.195 104.717 155.885 1.00 170.96 ? 355 THR R CG2 1 
ATOM 8511 N N   . LEU E 5 409 ? 115.628 105.794 155.123 1.00 170.25 ? 356 LEU R N   1 
ATOM 8512 C CA  . LEU E 5 409 ? 116.616 105.355 154.142 1.00 169.64 ? 356 LEU R CA  1 
ATOM 8513 C C   . LEU E 5 409 ? 116.054 104.270 153.233 1.00 169.20 ? 356 LEU R C   1 
ATOM 8514 O O   . LEU E 5 409 ? 116.286 104.285 152.018 1.00 168.38 ? 356 LEU R O   1 
ATOM 8515 C CB  . LEU E 5 409 ? 117.876 104.860 154.853 1.00 169.58 ? 356 LEU R CB  1 
ATOM 8516 C CG  . LEU E 5 409 ? 118.641 105.899 155.674 1.00 169.50 ? 356 LEU R CG  1 
ATOM 8517 C CD1 . LEU E 5 409 ? 119.870 105.275 156.318 1.00 168.36 ? 356 LEU R CD1 1 
ATOM 8518 C CD2 . LEU E 5 409 ? 119.031 107.086 154.808 1.00 169.21 ? 356 LEU R CD2 1 
ATOM 8519 N N   . THR E 5 410 ? 115.318 103.313 153.804 1.00 169.11 ? 357 THR R N   1 
ATOM 8520 C CA  . THR E 5 410 ? 114.718 102.258 152.993 1.00 168.72 ? 357 THR R CA  1 
ATOM 8521 C C   . THR E 5 410 ? 113.696 102.827 152.016 1.00 168.59 ? 357 THR R C   1 
ATOM 8522 O O   . THR E 5 410 ? 113.630 102.400 150.858 1.00 167.55 ? 357 THR R O   1 
ATOM 8523 C CB  . THR E 5 410 ? 114.071 101.204 153.891 1.00 168.74 ? 357 THR R CB  1 
ATOM 8524 O OG1 . THR E 5 410 ? 113.035 101.809 154.674 1.00 168.69 ? 357 THR R OG1 1 
ATOM 8525 C CG2 . THR E 5 410 ? 115.107 100.588 154.819 1.00 167.80 ? 357 THR R CG2 1 
ATOM 8526 N N   . PHE E 5 411 ? 112.890 103.792 152.466 1.00 160.06 ? 358 PHE R N   1 
ATOM 8527 C CA  . PHE E 5 411 ? 111.903 104.405 151.581 1.00 159.25 ? 358 PHE R CA  1 
ATOM 8528 C C   . PHE E 5 411 ? 112.576 105.134 150.425 1.00 159.15 ? 358 PHE R C   1 
ATOM 8529 O O   . PHE E 5 411 ? 112.107 105.068 149.283 1.00 158.84 ? 358 PHE R O   1 
ATOM 8530 C CB  . PHE E 5 411 ? 111.011 105.361 152.372 1.00 159.00 ? 358 PHE R CB  1 
ATOM 8531 C CG  . PHE E 5 411 ? 109.918 105.988 151.554 1.00 159.63 ? 358 PHE R CG  1 
ATOM 8532 C CD1 . PHE E 5 411 ? 108.730 105.313 151.327 1.00 158.26 ? 358 PHE R CD1 1 
ATOM 8533 C CD2 . PHE E 5 411 ? 110.076 107.254 151.013 1.00 158.56 ? 358 PHE R CD2 1 
ATOM 8534 C CE1 . PHE E 5 411 ? 107.723 105.888 150.575 1.00 158.16 ? 358 PHE R CE1 1 
ATOM 8535 C CE2 . PHE E 5 411 ? 109.073 107.833 150.261 1.00 157.67 ? 358 PHE R CE2 1 
ATOM 8536 C CZ  . PHE E 5 411 ? 107.895 107.150 150.042 1.00 158.14 ? 358 PHE R CZ  1 
ATOM 8537 N N   . VAL E 5 412 ? 113.672 105.844 150.704 1.00 161.32 ? 359 VAL R N   1 
ATOM 8538 C CA  . VAL E 5 412 ? 114.410 106.517 149.639 1.00 160.92 ? 359 VAL R CA  1 
ATOM 8539 C C   . VAL E 5 412 ? 114.980 105.497 148.662 1.00 160.64 ? 359 VAL R C   1 
ATOM 8540 O O   . VAL E 5 412 ? 114.928 105.688 147.440 1.00 160.67 ? 359 VAL R O   1 
ATOM 8541 C CB  . VAL E 5 412 ? 115.511 107.414 150.234 1.00 160.68 ? 359 VAL R CB  1 
ATOM 8542 C CG1 . VAL E 5 412 ? 116.384 107.991 149.131 1.00 159.37 ? 359 VAL R CG1 1 
ATOM 8543 C CG2 . VAL E 5 412 ? 114.892 108.528 151.064 1.00 160.35 ? 359 VAL R CG2 1 
ATOM 8544 N N   . TYR E 5 413 ? 115.532 104.398 149.182 1.00 159.12 ? 360 TYR R N   1 
ATOM 8545 C CA  . TYR E 5 413 ? 116.067 103.355 148.314 1.00 159.09 ? 360 TYR R CA  1 
ATOM 8546 C C   . TYR E 5 413 ? 114.974 102.740 147.449 1.00 158.08 ? 360 TYR R C   1 
ATOM 8547 O O   . TYR E 5 413 ? 115.190 102.465 146.263 1.00 157.23 ? 360 TYR R O   1 
ATOM 8548 C CB  . TYR E 5 413 ? 116.762 102.280 149.150 1.00 158.10 ? 360 TYR R CB  1 
ATOM 8549 C CG  . TYR E 5 413 ? 118.014 102.761 149.847 1.00 159.37 ? 360 TYR R CG  1 
ATOM 8550 C CD1 . TYR E 5 413 ? 118.727 103.851 149.363 1.00 158.76 ? 360 TYR R CD1 1 
ATOM 8551 C CD2 . TYR E 5 413 ? 118.484 102.126 150.989 1.00 159.27 ? 360 TYR R CD2 1 
ATOM 8552 C CE1 . TYR E 5 413 ? 119.872 104.294 149.997 1.00 158.65 ? 360 TYR R CE1 1 
ATOM 8553 C CE2 . TYR E 5 413 ? 119.628 102.562 151.630 1.00 159.54 ? 360 TYR R CE2 1 
ATOM 8554 C CZ  . TYR E 5 413 ? 120.318 103.646 151.130 1.00 159.26 ? 360 TYR R CZ  1 
ATOM 8555 O OH  . TYR E 5 413 ? 121.457 104.084 151.765 1.00 158.01 ? 360 TYR R OH  1 
ATOM 8556 N N   . LEU E 5 414 ? 113.793 102.511 148.027 1.00 151.13 ? 361 LEU R N   1 
ATOM 8557 C CA  . LEU E 5 414 ? 112.672 102.014 147.236 1.00 150.95 ? 361 LEU R CA  1 
ATOM 8558 C C   . LEU E 5 414 ? 112.265 103.020 146.167 1.00 150.54 ? 361 LEU R C   1 
ATOM 8559 O O   . LEU E 5 414 ? 111.937 102.638 145.037 1.00 149.98 ? 361 LEU R O   1 
ATOM 8560 C CB  . LEU E 5 414 ? 111.487 101.689 148.145 1.00 151.03 ? 361 LEU R CB  1 
ATOM 8561 C CG  . LEU E 5 414 ? 111.649 100.492 149.082 1.00 150.14 ? 361 LEU R CG  1 
ATOM 8562 C CD1 . LEU E 5 414 ? 110.406 100.312 149.937 1.00 149.84 ? 361 LEU R CD1 1 
ATOM 8563 C CD2 . LEU E 5 414 ? 111.945 99.228  148.291 1.00 149.30 ? 361 LEU R CD2 1 
ATOM 8564 N N   . TYR E 5 415 ? 112.279 104.311 146.506 1.00 141.18 ? 362 TYR R N   1 
ATOM 8565 C CA  . TYR E 5 415 ? 111.893 105.337 145.543 1.00 140.33 ? 362 TYR R CA  1 
ATOM 8566 C C   . TYR E 5 415 ? 112.851 105.376 144.359 1.00 140.17 ? 362 TYR R C   1 
ATOM 8567 O O   . TYR E 5 415 ? 112.424 105.553 143.212 1.00 140.15 ? 362 TYR R O   1 
ATOM 8568 C CB  . TYR E 5 415 ? 111.831 106.703 146.225 1.00 138.68 ? 362 TYR R CB  1 
ATOM 8569 C CG  . TYR E 5 415 ? 110.994 107.714 145.478 1.00 139.27 ? 362 TYR R CG  1 
ATOM 8570 C CD1 . TYR E 5 415 ? 111.551 108.515 144.491 1.00 138.89 ? 362 TYR R CD1 1 
ATOM 8571 C CD2 . TYR E 5 415 ? 109.643 107.865 145.759 1.00 140.78 ? 362 TYR R CD2 1 
ATOM 8572 C CE1 . TYR E 5 415 ? 110.787 109.439 143.806 1.00 139.85 ? 362 TYR R CE1 1 
ATOM 8573 C CE2 . TYR E 5 415 ? 108.871 108.786 145.080 1.00 140.03 ? 362 TYR R CE2 1 
ATOM 8574 C CZ  . TYR E 5 415 ? 109.447 109.570 144.104 1.00 140.25 ? 362 TYR R CZ  1 
ATOM 8575 O OH  . TYR E 5 415 ? 108.678 110.488 143.426 1.00 139.18 ? 362 TYR R OH  1 
ATOM 8576 N N   . ASN E 5 416 ? 114.152 105.225 144.617 1.00 143.41 ? 363 ASN R N   1 
ATOM 8577 C CA  . ASN E 5 416 ? 115.117 105.184 143.523 1.00 142.60 ? 363 ASN R CA  1 
ATOM 8578 C C   . ASN E 5 416 ? 114.875 103.980 142.622 1.00 143.06 ? 363 ASN R C   1 
ATOM 8579 O O   . ASN E 5 416 ? 114.954 104.089 141.393 1.00 143.51 ? 363 ASN R O   1 
ATOM 8580 C CB  . ASN E 5 416 ? 116.541 105.161 144.076 1.00 143.92 ? 363 ASN R CB  1 
ATOM 8581 C CG  . ASN E 5 416 ? 116.880 106.410 144.863 1.00 144.34 ? 363 ASN R CG  1 
ATOM 8582 O OD1 . ASN E 5 416 ? 117.196 107.452 144.290 1.00 143.50 ? 363 ASN R OD1 1 
ATOM 8583 N ND2 . ASN E 5 416 ? 116.822 106.310 146.186 1.00 144.59 ? 363 ASN R ND2 1 
ATOM 8584 N N   . ALA E 5 417 ? 114.584 102.821 143.216 1.00 139.75 ? 364 ALA R N   1 
ATOM 8585 C CA  . ALA E 5 417 ? 114.275 101.640 142.416 1.00 139.66 ? 364 ALA R CA  1 
ATOM 8586 C C   . ALA E 5 417 ? 112.977 101.822 141.639 1.00 138.54 ? 364 ALA R C   1 
ATOM 8587 O O   . ALA E 5 417 ? 112.852 101.340 140.508 1.00 138.23 ? 364 ALA R O   1 
ATOM 8588 C CB  . ALA E 5 417 ? 114.196 100.406 143.312 1.00 139.18 ? 364 ALA R CB  1 
ATOM 8589 N N   . ALA E 5 418 ? 111.999 102.511 142.232 1.00 130.53 ? 365 ALA R N   1 
ATOM 8590 C CA  . ALA E 5 418 ? 110.735 102.745 141.543 1.00 130.04 ? 365 ALA R CA  1 
ATOM 8591 C C   . ALA E 5 418 ? 110.933 103.586 140.289 1.00 129.87 ? 365 ALA R C   1 
ATOM 8592 O O   . ALA E 5 418 ? 110.313 103.324 139.252 1.00 131.42 ? 365 ALA R O   1 
ATOM 8593 C CB  . ALA E 5 418 ? 109.739 103.414 142.488 1.00 130.20 ? 365 ALA R CB  1 
ATOM 8594 N N   . ILE E 5 419 ? 111.790 104.607 140.365 1.00 127.89 ? 366 ILE R N   1 
ATOM 8595 C CA  . ILE E 5 419 ? 112.065 105.436 139.195 1.00 126.73 ? 366 ILE R CA  1 
ATOM 8596 C C   . ILE E 5 419 ? 112.730 104.612 138.101 1.00 126.38 ? 366 ILE R C   1 
ATOM 8597 O O   . ILE E 5 419 ? 112.436 104.779 136.912 1.00 127.15 ? 366 ILE R O   1 
ATOM 8598 C CB  . ILE E 5 419 ? 112.924 106.651 139.590 1.00 127.91 ? 366 ILE R CB  1 
ATOM 8599 C CG1 . ILE E 5 419 ? 112.191 107.509 140.622 1.00 129.23 ? 366 ILE R CG1 1 
ATOM 8600 C CG2 . ILE E 5 419 ? 113.271 107.481 138.365 1.00 126.63 ? 366 ILE R CG2 1 
ATOM 8601 C CD1 . ILE E 5 419 ? 112.966 108.732 141.056 1.00 128.38 ? 366 ILE R CD1 1 
ATOM 8602 N N   . SER E 5 420 ? 113.632 103.705 138.485 1.00 124.98 ? 367 SER R N   1 
ATOM 8603 C CA  . SER E 5 420 ? 114.314 102.872 137.500 1.00 125.87 ? 367 SER R CA  1 
ATOM 8604 C C   . SER E 5 420 ? 113.328 101.999 136.736 1.00 125.76 ? 367 SER R C   1 
ATOM 8605 O O   . SER E 5 420 ? 113.469 101.807 135.522 1.00 124.40 ? 367 SER R O   1 
ATOM 8606 C CB  . SER E 5 420 ? 115.373 102.011 138.186 1.00 125.71 ? 367 SER R CB  1 
ATOM 8607 O OG  . SER E 5 420 ? 114.784 101.143 139.138 1.00 125.07 ? 367 SER R OG  1 
ATOM 8608 N N   . LEU E 5 421 ? 112.327 101.453 137.429 1.00 118.98 ? 368 LEU R N   1 
ATOM 8609 C CA  . LEU E 5 421 ? 111.305 100.668 136.746 1.00 117.32 ? 368 LEU R CA  1 
ATOM 8610 C C   . LEU E 5 421 ? 110.457 101.534 135.825 1.00 117.13 ? 368 LEU R C   1 
ATOM 8611 O O   . LEU E 5 421 ? 109.938 101.039 134.818 1.00 117.32 ? 368 LEU R O   1 
ATOM 8612 C CB  . LEU E 5 421 ? 110.423 99.946  137.763 1.00 115.67 ? 368 LEU R CB  1 
ATOM 8613 C CG  . LEU E 5 421 ? 111.126 98.869  138.588 1.00 115.13 ? 368 LEU R CG  1 
ATOM 8614 C CD1 . LEU E 5 421 ? 110.145 98.183  139.522 1.00 114.59 ? 368 LEU R CD1 1 
ATOM 8615 C CD2 . LEU E 5 421 ? 111.795 97.859  137.674 1.00 114.70 ? 368 LEU R CD2 1 
ATOM 8616 N N   . GLY E 5 422 ? 110.298 102.816 136.152 1.00 114.90 ? 369 GLY R N   1 
ATOM 8617 C CA  . GLY E 5 422 ? 109.565 103.707 135.268 1.00 112.78 ? 369 GLY R CA  1 
ATOM 8618 C C   . GLY E 5 422 ? 110.236 103.863 133.918 1.00 112.01 ? 369 GLY R C   1 
ATOM 8619 O O   . GLY E 5 422 ? 109.569 103.883 132.881 1.00 113.88 ? 369 GLY R O   1 
ATOM 8620 N N   . TYR E 5 423 ? 111.564 103.978 133.912 1.00 113.99 ? 370 TYR R N   1 
ATOM 8621 C CA  . TYR E 5 423 ? 112.299 104.036 132.656 1.00 115.03 ? 370 TYR R CA  1 
ATOM 8622 C C   . TYR E 5 423 ? 112.384 102.676 131.981 1.00 114.36 ? 370 TYR R C   1 
ATOM 8623 O O   . TYR E 5 423 ? 112.659 102.610 130.779 1.00 114.07 ? 370 TYR R O   1 
ATOM 8624 C CB  . TYR E 5 423 ? 113.703 104.594 132.895 1.00 117.31 ? 370 TYR R CB  1 
ATOM 8625 C CG  . TYR E 5 423 ? 113.724 106.075 133.197 1.00 117.10 ? 370 TYR R CG  1 
ATOM 8626 C CD1 . TYR E 5 423 ? 113.429 106.549 134.466 1.00 116.63 ? 370 TYR R CD1 1 
ATOM 8627 C CD2 . TYR E 5 423 ? 114.039 106.999 132.211 1.00 115.98 ? 370 TYR R CD2 1 
ATOM 8628 C CE1 . TYR E 5 423 ? 113.443 107.900 134.746 1.00 115.00 ? 370 TYR R CE1 1 
ATOM 8629 C CE2 . TYR E 5 423 ? 114.055 108.352 132.481 1.00 115.97 ? 370 TYR R CE2 1 
ATOM 8630 C CZ  . TYR E 5 423 ? 113.757 108.797 133.750 1.00 116.76 ? 370 TYR R CZ  1 
ATOM 8631 O OH  . TYR E 5 423 ? 113.773 110.145 134.023 1.00 118.54 ? 370 TYR R OH  1 
ATOM 8632 N N   . ALA E 5 424 ? 112.158 101.592 132.727 1.00 110.36 ? 371 ALA R N   1 
ATOM 8633 C CA  . ALA E 5 424 ? 112.181 100.262 132.130 1.00 109.86 ? 371 ALA R CA  1 
ATOM 8634 C C   . ALA E 5 424 ? 110.981 100.029 131.222 1.00 107.21 ? 371 ALA R C   1 
ATOM 8635 O O   . ALA E 5 424 ? 111.061 99.221  130.290 1.00 107.11 ? 371 ALA R O   1 
ATOM 8636 C CB  . ALA E 5 424 ? 112.233 99.195  133.223 1.00 109.44 ? 371 ALA R CB  1 
ATOM 8637 N N   . ASN E 5 425 ? 109.867 100.721 131.475 1.00 100.76 ? 372 ASN R N   1 
ATOM 8638 C CA  . ASN E 5 425 ? 108.696 100.586 130.614 1.00 100.61 ? 372 ASN R CA  1 
ATOM 8639 C C   . ASN E 5 425 ? 109.005 101.025 129.190 1.00 101.34 ? 372 ASN R C   1 
ATOM 8640 O O   . ASN E 5 425 ? 108.595 100.367 128.227 1.00 104.26 ? 372 ASN R O   1 
ATOM 8641 C CB  . ASN E 5 425 ? 107.532 101.394 131.184 1.00 101.97 ? 372 ASN R CB  1 
ATOM 8642 C CG  . ASN E 5 425 ? 106.316 101.383 130.281 1.00 102.18 ? 372 ASN R CG  1 
ATOM 8643 O OD1 . ASN E 5 425 ? 106.139 102.271 129.448 1.00 100.71 ? 372 ASN R OD1 1 
ATOM 8644 N ND2 . ASN E 5 425 ? 105.470 100.375 130.442 1.00 100.98 ? 372 ASN R ND2 1 
ATOM 8645 N N   . SER E 5 426 ? 109.728 102.134 129.034 1.00 101.08 ? 373 SER R N   1 
ATOM 8646 C CA  . SER E 5 426 ? 110.148 102.566 127.708 1.00 99.90  ? 373 SER R CA  1 
ATOM 8647 C C   . SER E 5 426 ? 111.213 101.657 127.110 1.00 100.72 ? 373 SER R C   1 
ATOM 8648 O O   . SER E 5 426 ? 111.468 101.740 125.905 1.00 98.62  ? 373 SER R O   1 
ATOM 8649 C CB  . SER E 5 426 ? 110.660 104.004 127.769 1.00 101.95 ? 373 SER R CB  1 
ATOM 8650 O OG  . SER E 5 426 ? 109.649 104.879 128.234 1.00 100.94 ? 373 SER R OG  1 
ATOM 8651 N N   . CYS E 5 427 ? 111.838 100.804 127.920 1.00 103.95 ? 374 CYS R N   1 
ATOM 8652 C CA  . CYS E 5 427 ? 112.824 99.846  127.437 1.00 102.47 ? 374 CYS R CA  1 
ATOM 8653 C C   . CYS E 5 427 ? 112.189 98.519  127.043 1.00 103.79 ? 374 CYS R C   1 
ATOM 8654 O O   . CYS E 5 427 ? 112.619 97.891  126.070 1.00 103.51 ? 374 CYS R O   1 
ATOM 8655 C CB  . CYS E 5 427 ? 113.894 99.612  128.505 1.00 103.38 ? 374 CYS R CB  1 
ATOM 8656 S SG  . CYS E 5 427 ? 115.078 98.304  128.112 1.00 109.31 ? 374 CYS R SG  1 
ATOM 8657 N N   . LEU E 5 428 ? 111.170 98.077  127.782 1.00 102.15 ? 375 LEU R N   1 
ATOM 8658 C CA  . LEU E 5 428 ? 110.533 96.798  127.503 1.00 98.77  ? 375 LEU R CA  1 
ATOM 8659 C C   . LEU E 5 428 ? 109.484 96.880  126.402 1.00 97.83  ? 375 LEU R C   1 
ATOM 8660 O O   . LEU E 5 428 ? 109.206 95.861  125.762 1.00 101.23 ? 375 LEU R O   1 
ATOM 8661 C CB  . LEU E 5 428 ? 109.893 96.241  128.775 1.00 97.64  ? 375 LEU R CB  1 
ATOM 8662 C CG  . LEU E 5 428 ? 110.849 95.925  129.924 1.00 98.77  ? 375 LEU R CG  1 
ATOM 8663 C CD1 . LEU E 5 428 ? 110.091 95.369  131.117 1.00 97.23  ? 375 LEU R CD1 1 
ATOM 8664 C CD2 . LEU E 5 428 ? 111.921 94.952  129.469 1.00 98.74  ? 375 LEU R CD2 1 
ATOM 8665 N N   . ASN E 5 429 ? 108.894 98.053  126.169 1.00 95.56  ? 376 ASN R N   1 
ATOM 8666 C CA  . ASN E 5 429 ? 107.891 98.173  125.112 1.00 95.61  ? 376 ASN R CA  1 
ATOM 8667 C C   . ASN E 5 429 ? 108.430 97.815  123.733 1.00 98.31  ? 376 ASN R C   1 
ATOM 8668 O O   . ASN E 5 429 ? 107.758 97.053  123.017 1.00 102.45 ? 376 ASN R O   1 
ATOM 8669 C CB  . ASN E 5 429 ? 107.285 99.580  125.121 1.00 92.55  ? 376 ASN R CB  1 
ATOM 8670 C CG  . ASN E 5 429 ? 106.282 99.772  126.234 1.00 96.59  ? 376 ASN R CG  1 
ATOM 8671 O OD1 . ASN E 5 429 ? 105.662 98.816  126.694 1.00 95.62  ? 376 ASN R OD1 1 
ATOM 8672 N ND2 . ASN E 5 429 ? 106.107 101.014 126.665 1.00 100.40 ? 376 ASN R ND2 1 
ATOM 8673 N N   . PRO E 5 430 ? 109.584 98.320  123.283 1.00 97.34  ? 377 PRO R N   1 
ATOM 8674 C CA  . PRO E 5 430 ? 110.088 97.877  121.975 1.00 95.46  ? 377 PRO R CA  1 
ATOM 8675 C C   . PRO E 5 430 ? 110.398 96.393  121.923 1.00 99.10  ? 377 PRO R C   1 
ATOM 8676 O O   . PRO E 5 430 ? 110.225 95.771  120.868 1.00 100.04 ? 377 PRO R O   1 
ATOM 8677 C CB  . PRO E 5 430 ? 111.348 98.729  121.776 1.00 98.33  ? 377 PRO R CB  1 
ATOM 8678 C CG  . PRO E 5 430 ? 111.764 99.108  123.144 1.00 98.97  ? 377 PRO R CG  1 
ATOM 8679 C CD  . PRO E 5 430 ? 110.491 99.305  123.899 1.00 99.90  ? 377 PRO R CD  1 
ATOM 8680 N N   . PHE E 5 431 ? 110.851 95.802  123.030 1.00 100.69 ? 378 PHE R N   1 
ATOM 8681 C CA  . PHE E 5 431 ? 111.176 94.381  123.032 1.00 100.33 ? 378 PHE R CA  1 
ATOM 8682 C C   . PHE E 5 431 ? 109.933 93.503  123.056 1.00 98.91  ? 378 PHE R C   1 
ATOM 8683 O O   . PHE E 5 431 ? 109.990 92.352  122.611 1.00 101.36 ? 378 PHE R O   1 
ATOM 8684 C CB  . PHE E 5 431 ? 112.086 94.049  124.214 1.00 100.18 ? 378 PHE R CB  1 
ATOM 8685 C CG  . PHE E 5 431 ? 113.518 94.437  123.995 1.00 101.07 ? 378 PHE R CG  1 
ATOM 8686 C CD1 . PHE E 5 431 ? 113.971 95.694  124.348 1.00 102.81 ? 378 PHE R CD1 1 
ATOM 8687 C CD2 . PHE E 5 431 ? 114.409 93.547  123.424 1.00 100.19 ? 378 PHE R CD2 1 
ATOM 8688 C CE1 . PHE E 5 431 ? 115.285 96.055  124.143 1.00 101.62 ? 378 PHE R CE1 1 
ATOM 8689 C CE2 . PHE E 5 431 ? 115.725 93.902  123.217 1.00 101.02 ? 378 PHE R CE2 1 
ATOM 8690 C CZ  . PHE E 5 431 ? 116.163 95.158  123.576 1.00 100.72 ? 378 PHE R CZ  1 
ATOM 8691 N N   . VAL E 5 432 ? 108.814 94.013  123.573 1.00 90.53  ? 379 VAL R N   1 
ATOM 8692 C CA  . VAL E 5 432 ? 107.565 93.261  123.499 1.00 88.54  ? 379 VAL R CA  1 
ATOM 8693 C C   . VAL E 5 432 ? 107.143 93.089  122.047 1.00 89.60  ? 379 VAL R C   1 
ATOM 8694 O O   . VAL E 5 432 ? 106.724 92.003  121.628 1.00 93.45  ? 379 VAL R O   1 
ATOM 8695 C CB  . VAL E 5 432 ? 106.472 93.953  124.334 1.00 85.10  ? 379 VAL R CB  1 
ATOM 8696 C CG1 . VAL E 5 432 ? 105.113 93.361  124.023 1.00 88.72  ? 379 VAL R CG1 1 
ATOM 8697 C CG2 . VAL E 5 432 ? 106.774 93.811  125.814 1.00 86.47  ? 379 VAL R CG2 1 
ATOM 8698 N N   . TYR E 5 433 ? 107.259 94.154  121.254 1.00 88.59  ? 380 TYR R N   1 
ATOM 8699 C CA  . TYR E 5 433 ? 106.911 94.076  119.840 1.00 88.59  ? 380 TYR R CA  1 
ATOM 8700 C C   . TYR E 5 433 ? 107.860 93.154  119.082 1.00 93.56  ? 380 TYR R C   1 
ATOM 8701 O O   . TYR E 5 433 ? 107.430 92.396  118.207 1.00 93.62  ? 380 TYR R O   1 
ATOM 8702 C CB  . TYR E 5 433 ? 106.925 95.478  119.235 1.00 88.18  ? 380 TYR R CB  1 
ATOM 8703 C CG  . TYR E 5 433 ? 106.152 95.623  117.946 1.00 89.01  ? 380 TYR R CG  1 
ATOM 8704 C CD1 . TYR E 5 433 ? 104.796 95.917  117.960 1.00 91.43  ? 380 TYR R CD1 1 
ATOM 8705 C CD2 . TYR E 5 433 ? 106.781 95.487  116.718 1.00 91.51  ? 380 TYR R CD2 1 
ATOM 8706 C CE1 . TYR E 5 433 ? 104.085 96.063  116.786 1.00 93.68  ? 380 TYR R CE1 1 
ATOM 8707 C CE2 . TYR E 5 433 ? 106.078 95.630  115.538 1.00 93.67  ? 380 TYR R CE2 1 
ATOM 8708 C CZ  . TYR E 5 433 ? 104.731 95.918  115.578 1.00 94.32  ? 380 TYR R CZ  1 
ATOM 8709 O OH  . TYR E 5 433 ? 104.027 96.062  114.404 1.00 90.30  ? 380 TYR R OH  1 
ATOM 8710 N N   . ILE E 5 434 ? 109.155 93.206  119.401 1.00 100.21 ? 381 ILE R N   1 
ATOM 8711 C CA  . ILE E 5 434 ? 110.139 92.403  118.679 1.00 98.74  ? 381 ILE R CA  1 
ATOM 8712 C C   . ILE E 5 434 ? 109.955 90.919  118.979 1.00 99.00  ? 381 ILE R C   1 
ATOM 8713 O O   . ILE E 5 434 ? 109.970 90.079  118.072 1.00 101.30 ? 381 ILE R O   1 
ATOM 8714 C CB  . ILE E 5 434 ? 111.565 92.870  119.018 1.00 100.62 ? 381 ILE R CB  1 
ATOM 8715 C CG1 . ILE E 5 434 ? 111.795 94.295  118.516 1.00 99.85  ? 381 ILE R CG1 1 
ATOM 8716 C CG2 . ILE E 5 434 ? 112.592 91.924  118.424 1.00 100.63 ? 381 ILE R CG2 1 
ATOM 8717 C CD1 . ILE E 5 434 ? 113.170 94.834  118.833 1.00 99.69  ? 381 ILE R CD1 1 
ATOM 8718 N N   . VAL E 5 435 ? 109.782 90.574  120.253 1.00 94.22  ? 382 VAL R N   1 
ATOM 8719 C CA  . VAL E 5 435 ? 109.782 89.170  120.650 1.00 95.25  ? 382 VAL R CA  1 
ATOM 8720 C C   . VAL E 5 435 ? 108.435 88.517  120.368 1.00 97.25  ? 382 VAL R C   1 
ATOM 8721 O O   . VAL E 5 435 ? 108.369 87.419  119.804 1.00 98.14  ? 382 VAL R O   1 
ATOM 8722 C CB  . VAL E 5 435 ? 110.172 89.039  122.133 1.00 93.84  ? 382 VAL R CB  1 
ATOM 8723 C CG1 . VAL E 5 435 ? 110.019 87.601  122.596 1.00 93.37  ? 382 VAL R CG1 1 
ATOM 8724 C CG2 . VAL E 5 435 ? 111.597 89.519  122.347 1.00 93.22  ? 382 VAL R CG2 1 
ATOM 8725 N N   . LEU E 5 436 ? 107.344 89.175  120.748 1.00 90.71  ? 383 LEU R N   1 
ATOM 8726 C CA  . LEU E 5 436 ? 106.029 88.549  120.716 1.00 88.55  ? 383 LEU R CA  1 
ATOM 8727 C C   . LEU E 5 436 ? 105.333 88.638  119.365 1.00 91.84  ? 383 LEU R C   1 
ATOM 8728 O O   . LEU E 5 436 ? 104.254 88.057  119.209 1.00 93.17  ? 383 LEU R O   1 
ATOM 8729 C CB  . LEU E 5 436 ? 105.131 89.164  121.790 1.00 85.96  ? 383 LEU R CB  1 
ATOM 8730 C CG  . LEU E 5 436 ? 105.658 89.003  123.214 1.00 88.54  ? 383 LEU R CG  1 
ATOM 8731 C CD1 . LEU E 5 436 ? 104.698 89.626  124.199 1.00 90.77  ? 383 LEU R CD1 1 
ATOM 8732 C CD2 . LEU E 5 436 ? 105.886 87.538  123.539 1.00 89.06  ? 383 LEU R CD2 1 
ATOM 8733 N N   . CYS E 5 437 ? 105.905 89.339  118.391 1.00 93.64  ? 384 CYS R N   1 
ATOM 8734 C CA  . CYS E 5 437 ? 105.318 89.446  117.059 1.00 93.64  ? 384 CYS R CA  1 
ATOM 8735 C C   . CYS E 5 437 ? 106.206 88.688  116.082 1.00 98.71  ? 384 CYS R C   1 
ATOM 8736 O O   . CYS E 5 437 ? 107.306 89.144  115.752 1.00 100.57 ? 384 CYS R O   1 
ATOM 8737 C CB  . CYS E 5 437 ? 105.161 90.905  116.641 1.00 95.33  ? 384 CYS R CB  1 
ATOM 8738 S SG  . CYS E 5 437 ? 104.407 91.135  115.016 1.00 103.28 ? 384 CYS R SG  1 
ATOM 8739 N N   . GLU E 5 438 ? 105.725 87.532  115.621 1.00 112.29 ? 385 GLU R N   1 
ATOM 8740 C CA  . GLU E 5 438 ? 106.495 86.733  114.674 1.00 112.47 ? 385 GLU R CA  1 
ATOM 8741 C C   . GLU E 5 438 ? 106.624 87.437  113.329 1.00 114.03 ? 385 GLU R C   1 
ATOM 8742 O O   . GLU E 5 438 ? 107.674 87.358  112.681 1.00 116.81 ? 385 GLU R O   1 
ATOM 8743 C CB  . GLU E 5 438 ? 105.851 85.358  114.501 1.00 109.03 ? 385 GLU R CB  1 
ATOM 8744 N N   . THR E 5 439 ? 105.565 88.120  112.888 1.00 107.15 ? 386 THR R N   1 
ATOM 8745 C CA  . THR E 5 439 ? 105.605 88.805  111.599 1.00 108.24 ? 386 THR R CA  1 
ATOM 8746 C C   . THR E 5 439 ? 106.677 89.887  111.582 1.00 109.99 ? 386 THR R C   1 
ATOM 8747 O O   . THR E 5 439 ? 107.459 89.989  110.630 1.00 110.92 ? 386 THR R O   1 
ATOM 8748 C CB  . THR E 5 439 ? 104.236 89.404  111.283 1.00 108.83 ? 386 THR R CB  1 
ATOM 8749 O OG1 . THR E 5 439 ? 103.251 88.365  111.266 1.00 109.48 ? 386 THR R OG1 1 
ATOM 8750 C CG2 . THR E 5 439 ? 104.260 90.095  109.930 1.00 106.78 ? 386 THR R CG2 1 
ATOM 8751 N N   . PHE E 5 440 ? 106.726 90.712  112.629 1.00 110.93 ? 387 PHE R N   1 
ATOM 8752 C CA  . PHE E 5 440 ? 107.762 91.735  112.712 1.00 110.67 ? 387 PHE R CA  1 
ATOM 8753 C C   . PHE E 5 440 ? 109.139 91.112  112.885 1.00 112.80 ? 387 PHE R C   1 
ATOM 8754 O O   . PHE E 5 440 ? 110.117 91.575  112.287 1.00 115.38 ? 387 PHE R O   1 
ATOM 8755 C CB  . PHE E 5 440 ? 107.462 92.695  113.861 1.00 110.21 ? 387 PHE R CB  1 
ATOM 8756 C CG  . PHE E 5 440 ? 108.517 93.744  114.066 1.00 111.96 ? 387 PHE R CG  1 
ATOM 8757 C CD1 . PHE E 5 440 ? 108.548 94.877  113.272 1.00 110.63 ? 387 PHE R CD1 1 
ATOM 8758 C CD2 . PHE E 5 440 ? 109.475 93.599  115.055 1.00 110.79 ? 387 PHE R CD2 1 
ATOM 8759 C CE1 . PHE E 5 440 ? 109.514 95.842  113.460 1.00 110.73 ? 387 PHE R CE1 1 
ATOM 8760 C CE2 . PHE E 5 440 ? 110.443 94.561  115.245 1.00 109.02 ? 387 PHE R CE2 1 
ATOM 8761 C CZ  . PHE E 5 440 ? 110.463 95.684  114.447 1.00 110.62 ? 387 PHE R CZ  1 
ATOM 8762 N N   . ARG E 5 441 ? 109.236 90.065  113.707 1.00 114.12 ? 388 ARG R N   1 
ATOM 8763 C CA  . ARG E 5 441 ? 110.523 89.420  113.939 1.00 114.78 ? 388 ARG R CA  1 
ATOM 8764 C C   . ARG E 5 441 ? 111.069 88.796  112.660 1.00 116.74 ? 388 ARG R C   1 
ATOM 8765 O O   . ARG E 5 441 ? 112.270 88.887  112.380 1.00 117.49 ? 388 ARG R O   1 
ATOM 8766 C CB  . ARG E 5 441 ? 110.381 88.373  115.043 1.00 113.60 ? 388 ARG R CB  1 
ATOM 8767 C CG  . ARG E 5 441 ? 111.655 87.631  115.383 1.00 114.67 ? 388 ARG R CG  1 
ATOM 8768 C CD  . ARG E 5 441 ? 111.465 86.794  116.635 1.00 114.84 ? 388 ARG R CD  1 
ATOM 8769 N NE  . ARG E 5 441 ? 110.303 85.919  116.532 1.00 115.82 ? 388 ARG R NE  1 
ATOM 8770 C CZ  . ARG E 5 441 ? 109.848 85.160  117.520 1.00 116.11 ? 388 ARG R CZ  1 
ATOM 8771 N NH1 . ARG E 5 441 ? 110.435 85.141  118.705 1.00 115.18 ? 388 ARG R NH1 1 
ATOM 8772 N NH2 . ARG E 5 441 ? 108.776 84.400  117.313 1.00 115.66 ? 388 ARG R NH2 1 
ATOM 8773 N N   . LYS E 5 442 ? 110.203 88.154  111.872 1.00 124.17 ? 389 LYS R N   1 
ATOM 8774 C CA  . LYS E 5 442 ? 110.646 87.572  110.608 1.00 123.70 ? 389 LYS R CA  1 
ATOM 8775 C C   . LYS E 5 442 ? 111.088 88.650  109.626 1.00 125.13 ? 389 LYS R C   1 
ATOM 8776 O O   . LYS E 5 442 ? 112.102 88.490  108.937 1.00 126.12 ? 389 LYS R O   1 
ATOM 8777 C CB  . LYS E 5 442 ? 109.531 86.720  110.003 1.00 121.73 ? 389 LYS R CB  1 
ATOM 8778 N N   . ARG E 5 443 ? 110.341 89.753  109.547 1.00 121.66 ? 390 ARG R N   1 
ATOM 8779 C CA  . ARG E 5 443 ? 110.711 90.837  108.642 1.00 120.50 ? 390 ARG R CA  1 
ATOM 8780 C C   . ARG E 5 443 ? 111.999 91.515  109.090 1.00 121.53 ? 390 ARG R C   1 
ATOM 8781 O O   . ARG E 5 443 ? 112.803 91.947  108.255 1.00 121.44 ? 390 ARG R O   1 
ATOM 8782 C CB  . ARG E 5 443 ? 109.573 91.852  108.543 1.00 119.69 ? 390 ARG R CB  1 
ATOM 8783 C CG  . ARG E 5 443 ? 109.874 93.033  107.635 1.00 121.13 ? 390 ARG R CG  1 
ATOM 8784 C CD  . ARG E 5 443 ? 108.663 93.937  107.460 1.00 121.53 ? 390 ARG R CD  1 
ATOM 8785 N NE  . ARG E 5 443 ? 107.611 93.305  106.672 1.00 124.12 ? 390 ARG R NE  1 
ATOM 8786 C CZ  . ARG E 5 443 ? 106.536 92.721  107.183 1.00 123.47 ? 390 ARG R CZ  1 
ATOM 8787 N NH1 . ARG E 5 443 ? 106.330 92.673  108.489 1.00 125.34 ? 390 ARG R NH1 1 
ATOM 8788 N NH2 . ARG E 5 443 ? 105.644 92.172  106.364 1.00 119.05 ? 390 ARG R NH2 1 
ATOM 8789 N N   . LEU E 5 444 ? 112.210 91.624  110.403 1.00 127.73 ? 391 LEU R N   1 
ATOM 8790 C CA  . LEU E 5 444 ? 113.432 92.239  110.909 1.00 127.54 ? 391 LEU R CA  1 
ATOM 8791 C C   . LEU E 5 444 ? 114.662 91.438  110.503 1.00 129.26 ? 391 LEU R C   1 
ATOM 8792 O O   . LEU E 5 444 ? 115.691 92.014  110.131 1.00 127.49 ? 391 LEU R O   1 
ATOM 8793 C CB  . LEU E 5 444 ? 113.357 92.374  112.430 1.00 126.32 ? 391 LEU R CB  1 
ATOM 8794 C CG  . LEU E 5 444 ? 114.555 93.021  113.123 1.00 126.70 ? 391 LEU R CG  1 
ATOM 8795 C CD1 . LEU E 5 444 ? 114.762 94.440  112.619 1.00 128.35 ? 391 LEU R CD1 1 
ATOM 8796 C CD2 . LEU E 5 444 ? 114.373 93.004  114.632 1.00 125.48 ? 391 LEU R CD2 1 
ATOM 8797 N N   . VAL E 5 445 ? 114.575 90.108  110.568 1.00 137.04 ? 392 VAL R N   1 
ATOM 8798 C CA  . VAL E 5 445 ? 115.698 89.266  110.163 1.00 136.63 ? 392 VAL R CA  1 
ATOM 8799 C C   . VAL E 5 445 ? 115.973 89.423  108.672 1.00 135.98 ? 392 VAL R C   1 
ATOM 8800 O O   . VAL E 5 445 ? 117.131 89.482  108.242 1.00 135.55 ? 392 VAL R O   1 
ATOM 8801 C CB  . VAL E 5 445 ? 115.428 87.798  110.541 1.00 133.87 ? 392 VAL R CB  1 
ATOM 8802 C CG1 . VAL E 5 445 ? 116.541 86.901  110.025 1.00 133.43 ? 392 VAL R CG1 1 
ATOM 8803 C CG2 . VAL E 5 445 ? 115.287 87.658  112.048 1.00 132.61 ? 392 VAL R CG2 1 
ATOM 8804 N N   . LEU E 5 446 ? 114.913 89.494  107.862 1.00 138.36 ? 393 LEU R N   1 
ATOM 8805 C CA  . LEU E 5 446 ? 115.088 89.635  106.420 1.00 138.17 ? 393 LEU R CA  1 
ATOM 8806 C C   . LEU E 5 446 ? 115.788 90.942  106.069 1.00 139.70 ? 393 LEU R C   1 
ATOM 8807 O O   . LEU E 5 446 ? 116.652 90.974  105.184 1.00 138.88 ? 393 LEU R O   1 
ATOM 8808 C CB  . LEU E 5 446 ? 113.734 89.545  105.717 1.00 136.59 ? 393 LEU R CB  1 
ATOM 8809 N N   . SER E 5 447 ? 115.429 92.033  106.749 1.00 141.00 ? 394 SER R N   1 
ATOM 8810 C CA  . SER E 5 447 ? 116.066 93.317  106.485 1.00 139.45 ? 394 SER R CA  1 
ATOM 8811 C C   . SER E 5 447 ? 117.511 93.361  106.966 1.00 138.85 ? 394 SER R C   1 
ATOM 8812 O O   . SER E 5 447 ? 118.267 94.238  106.535 1.00 136.84 ? 394 SER R O   1 
ATOM 8813 C CB  . SER E 5 447 ? 115.266 94.447  107.136 1.00 138.24 ? 394 SER R CB  1 
ATOM 8814 O OG  . SER E 5 447 ? 113.956 94.518  106.601 1.00 136.66 ? 394 SER R OG  1 
ATOM 8815 N N   . VAL E 5 448 ? 117.908 92.446  107.845 1.00 142.80 ? 395 VAL R N   1 
ATOM 8816 C CA  . VAL E 5 448 ? 119.280 92.399  108.333 1.00 143.22 ? 395 VAL R CA  1 
ATOM 8817 C C   . VAL E 5 448 ? 120.069 91.336  107.580 1.00 142.39 ? 395 VAL R C   1 
ATOM 8818 O O   . VAL E 5 448 ? 119.508 90.574  106.794 1.00 141.94 ? 395 VAL R O   1 
ATOM 8819 C CB  . VAL E 5 448 ? 119.326 92.137  109.848 1.00 142.97 ? 395 VAL R CB  1 
ATOM 8820 C CG1 . VAL E 5 448 ? 120.759 91.919  110.304 1.00 141.86 ? 395 VAL R CG1 1 
ATOM 8821 C CG2 . VAL E 5 448 ? 118.694 93.295  110.604 1.00 142.52 ? 395 VAL R CG2 1 
# 
