data_8WS9
# 
_entry.id   8WS9 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8WS9         pdb_00008ws9 10.2210/pdb8ws9/pdb 
WWPDB D_1300041558 ?            ?                   
EMDB  EMD-37802    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-04-16 ? 
2 'EM metadata'     1 0 2025-04-16 ? 
3 'Half map'        1 0 2025-04-16 1 
4 'Half map'        1 0 2025-04-16 2 
5 Image             1 0 2025-04-16 ? 
6 'Primary map'     1 0 2025-04-16 ? 
7 'Structure model' 1 1 2025-06-18 ? 
8 'EM metadata'     1 1 2025-06-18 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Half map'        repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 Image             repository 'Initial release' ? ? 
6 6 'Primary map'     repository 'Initial release' ? ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 7 'Structure model' 'Data collection'      
2 8 'EM metadata'     'Data processing'      
3 8 'EM metadata'     'Experimental summary' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 7 'Structure model' em_admin    
2 7 'Structure model' em_software 
3 8 'EM metadata'     em_admin    
4 8 'EM metadata'     em_software 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 7 'Structure model' '_em_admin.last_update' 
2 7 'Structure model' '_em_software.name'     
3 8 'EM metadata'     '_em_admin.last_update' 
4 8 'EM metadata'     '_em_software.name'     
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8WS9 
_pdbx_database_status.recvd_initial_deposition_date   2023-10-17 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM mini structure of Cas12-1 with 5 nt complementary heteroduplex' 
_pdbx_database_related.db_id          EMD-37802 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              zhangk@sustech.edu.cn 
_pdbx_contact_author.name_first         Zhang 
_pdbx_contact_author.name_last          Kuo 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-2875-2581 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Kuo, Z.' 1 ? 
'Xi, Z.'  2 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Cryo-EM mini structure of Cas12-1 with 5 nt complementary heteroduplex' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Kuo, Z.' 1 ? 
primary 'Xi, Z.'  2 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man Cas12-1 83449.094 1 ? ? ? ? 
2 polymer man crRNA   14652.684 1 ? ? ? ? 
3 polymer man TS      13012.336 1 ? ? ? ? 
4 polymer man NTS     12852.241 1 ? ? ? ? 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)'        no no 
;MTPKTETPVGALIKKFFPGKRFQKNYLKDAGKKLKREGEAAAVEYLSGKQEDHPANFCPPAKVNILAQSRPLSEWPINLV
SKGVQEYVYGLTAAEREANGDFGTSRKSLDRWFARTGVPTHGYTTVQGLNLILRHTFNRYDGVIKKVETRNEKRRSKATR
INVSREADGLPPIEAEPEETAFGPDGKLKERPGINPSIYCYQQVSPVPYNPAKHPALPFSGVDPGAPLPLGTPNRLSIPK
GQPGYVPEWQRPHLSTKNKRIRKWYARANWRRKPGRKSVLDEAKLKEAALKEAIPIIVTIGKDWIVMDARGLLRAVYWRG
IAKPGLSLKELLGFFSGDPVLDPKRGIATFTFKLGAVAVHSRKPTRGKKSKELLLSMTAEKPHVGLVAIDLGQTNPVAAE
FSRVKREGETLQAEPLGQIVLPDDLVKDLTRYRRAWDATEEQIKAEAIVQLPEECRAEVVKVNQMSAEETKHLILDRGVS
GDLPWEKMTSNTTFISDHLLAKGVTDQVFFEKKSKGKKKGTETVKRKDYGWVKLLRPRLSQETRKAVNDKTWELKRASTE
YVRLSRRKTELARRCVNYIVRETKRWTQCEDIAIVIEDLNVRFFHGSGERPDGWDNFFISKRENRWFIQVLHKAFSDLAL
HRGLPVIEANPARTSITCIRCGHCDRNNRHGEMFLCLSCNDLRHADREIATRNLTRVAVTGEMIPRRIEPGEQSGDTKKA
RSARKGKKAVISKREAA
;
;MTPKTETPVGALIKKFFPGKRFQKNYLKDAGKKLKREGEAAAVEYLSGKQEDHPANFCPPAKVNILAQSRPLSEWPINLV
SKGVQEYVYGLTAAEREANGDFGTSRKSLDRWFARTGVPTHGYTTVQGLNLILRHTFNRYDGVIKKVETRNEKRRSKATR
INVSREADGLPPIEAEPEETAFGPDGKLKERPGINPSIYCYQQVSPVPYNPAKHPALPFSGVDPGAPLPLGTPNRLSIPK
GQPGYVPEWQRPHLSTKNKRIRKWYARANWRRKPGRKSVLDEAKLKEAALKEAIPIIVTIGKDWIVMDARGLLRAVYWRG
IAKPGLSLKELLGFFSGDPVLDPKRGIATFTFKLGAVAVHSRKPTRGKKSKELLLSMTAEKPHVGLVAIDLGQTNPVAAE
FSRVKREGETLQAEPLGQIVLPDDLVKDLTRYRRAWDATEEQIKAEAIVQLPEECRAEVVKVNQMSAEETKHLILDRGVS
GDLPWEKMTSNTTFISDHLLAKGVTDQVFFEKKSKGKKKGTETVKRKDYGWVKLLRPRLSQETRKAVNDKTWELKRASTE
YVRLSRRKTELARRCVNYIVRETKRWTQCEDIAIVIEDLNVRFFHGSGERPDGWDNFFISKRENRWFIQVLHKAFSDLAL
HRGLPVIEANPARTSITCIRCGHCDRNNRHGEMFLCLSCNDLRHADREIATRNLTRVAVTGEMIPRRIEPGEQSGDTKKA
RSARKGKKAVISKREAA
;
A ? 
2 polyribonucleotide      no no UCAACGCUUGCUCGGUUCGCCGAGACUCCCCUACGUGCUGCUGAAG UCAACGCUUGCUCGGUUCGCCGAGACUCCCCUACGUGCUGCUGAAG B ? 
3 polydeoxyribonucleotide no no 
;(DC)(DT)(DG)(DC)(DC)(DC)(DT)(DT)(DG)(DC)(DA)(DA)(DG)(DA)(DA)(DG)(DT)(DC)(DG)(DT)
(DC)(DG)(DT)(DG)(DC)(DA)(DT)(DG)(DG)(DG)(DG)(DA)(DG)(DA)(DA)(DT)(DT)(DG)(DG)(DC)
(DC)(DA)
;
CTGCCCTTGCAAGAAGTCGTCGTGCATGGGGAGAATTGGCCA C ? 
4 polydeoxyribonucleotide no no 
;(DT)(DG)(DG)(DC)(DC)(DA)(DA)(DT)(DT)(DC)(DT)(DC)(DC)(DC)(DC)(DA)(DT)(DG)(DC)(DA)
(DC)(DG)(DA)(DC)(DG)(DA)(DC)(DT)(DT)(DC)(DT)(DT)(DG)(DC)(DA)(DA)(DG)(DG)(DG)(DC)
(DA)(DG)
;
TGGCCAATTCTCCCCATGCACGACGACTTCTTGCAAGGGCAG D ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   THR n 
1 3   PRO n 
1 4   LYS n 
1 5   THR n 
1 6   GLU n 
1 7   THR n 
1 8   PRO n 
1 9   VAL n 
1 10  GLY n 
1 11  ALA n 
1 12  LEU n 
1 13  ILE n 
1 14  LYS n 
1 15  LYS n 
1 16  PHE n 
1 17  PHE n 
1 18  PRO n 
1 19  GLY n 
1 20  LYS n 
1 21  ARG n 
1 22  PHE n 
1 23  GLN n 
1 24  LYS n 
1 25  ASN n 
1 26  TYR n 
1 27  LEU n 
1 28  LYS n 
1 29  ASP n 
1 30  ALA n 
1 31  GLY n 
1 32  LYS n 
1 33  LYS n 
1 34  LEU n 
1 35  LYS n 
1 36  ARG n 
1 37  GLU n 
1 38  GLY n 
1 39  GLU n 
1 40  ALA n 
1 41  ALA n 
1 42  ALA n 
1 43  VAL n 
1 44  GLU n 
1 45  TYR n 
1 46  LEU n 
1 47  SER n 
1 48  GLY n 
1 49  LYS n 
1 50  GLN n 
1 51  GLU n 
1 52  ASP n 
1 53  HIS n 
1 54  PRO n 
1 55  ALA n 
1 56  ASN n 
1 57  PHE n 
1 58  CYS n 
1 59  PRO n 
1 60  PRO n 
1 61  ALA n 
1 62  LYS n 
1 63  VAL n 
1 64  ASN n 
1 65  ILE n 
1 66  LEU n 
1 67  ALA n 
1 68  GLN n 
1 69  SER n 
1 70  ARG n 
1 71  PRO n 
1 72  LEU n 
1 73  SER n 
1 74  GLU n 
1 75  TRP n 
1 76  PRO n 
1 77  ILE n 
1 78  ASN n 
1 79  LEU n 
1 80  VAL n 
1 81  SER n 
1 82  LYS n 
1 83  GLY n 
1 84  VAL n 
1 85  GLN n 
1 86  GLU n 
1 87  TYR n 
1 88  VAL n 
1 89  TYR n 
1 90  GLY n 
1 91  LEU n 
1 92  THR n 
1 93  ALA n 
1 94  ALA n 
1 95  GLU n 
1 96  ARG n 
1 97  GLU n 
1 98  ALA n 
1 99  ASN n 
1 100 GLY n 
1 101 ASP n 
1 102 PHE n 
1 103 GLY n 
1 104 THR n 
1 105 SER n 
1 106 ARG n 
1 107 LYS n 
1 108 SER n 
1 109 LEU n 
1 110 ASP n 
1 111 ARG n 
1 112 TRP n 
1 113 PHE n 
1 114 ALA n 
1 115 ARG n 
1 116 THR n 
1 117 GLY n 
1 118 VAL n 
1 119 PRO n 
1 120 THR n 
1 121 HIS n 
1 122 GLY n 
1 123 TYR n 
1 124 THR n 
1 125 THR n 
1 126 VAL n 
1 127 GLN n 
1 128 GLY n 
1 129 LEU n 
1 130 ASN n 
1 131 LEU n 
1 132 ILE n 
1 133 LEU n 
1 134 ARG n 
1 135 HIS n 
1 136 THR n 
1 137 PHE n 
1 138 ASN n 
1 139 ARG n 
1 140 TYR n 
1 141 ASP n 
1 142 GLY n 
1 143 VAL n 
1 144 ILE n 
1 145 LYS n 
1 146 LYS n 
1 147 VAL n 
1 148 GLU n 
1 149 THR n 
1 150 ARG n 
1 151 ASN n 
1 152 GLU n 
1 153 LYS n 
1 154 ARG n 
1 155 ARG n 
1 156 SER n 
1 157 LYS n 
1 158 ALA n 
1 159 THR n 
1 160 ARG n 
1 161 ILE n 
1 162 ASN n 
1 163 VAL n 
1 164 SER n 
1 165 ARG n 
1 166 GLU n 
1 167 ALA n 
1 168 ASP n 
1 169 GLY n 
1 170 LEU n 
1 171 PRO n 
1 172 PRO n 
1 173 ILE n 
1 174 GLU n 
1 175 ALA n 
1 176 GLU n 
1 177 PRO n 
1 178 GLU n 
1 179 GLU n 
1 180 THR n 
1 181 ALA n 
1 182 PHE n 
1 183 GLY n 
1 184 PRO n 
1 185 ASP n 
1 186 GLY n 
1 187 LYS n 
1 188 LEU n 
1 189 LYS n 
1 190 GLU n 
1 191 ARG n 
1 192 PRO n 
1 193 GLY n 
1 194 ILE n 
1 195 ASN n 
1 196 PRO n 
1 197 SER n 
1 198 ILE n 
1 199 TYR n 
1 200 CYS n 
1 201 TYR n 
1 202 GLN n 
1 203 GLN n 
1 204 VAL n 
1 205 SER n 
1 206 PRO n 
1 207 VAL n 
1 208 PRO n 
1 209 TYR n 
1 210 ASN n 
1 211 PRO n 
1 212 ALA n 
1 213 LYS n 
1 214 HIS n 
1 215 PRO n 
1 216 ALA n 
1 217 LEU n 
1 218 PRO n 
1 219 PHE n 
1 220 SER n 
1 221 GLY n 
1 222 VAL n 
1 223 ASP n 
1 224 PRO n 
1 225 GLY n 
1 226 ALA n 
1 227 PRO n 
1 228 LEU n 
1 229 PRO n 
1 230 LEU n 
1 231 GLY n 
1 232 THR n 
1 233 PRO n 
1 234 ASN n 
1 235 ARG n 
1 236 LEU n 
1 237 SER n 
1 238 ILE n 
1 239 PRO n 
1 240 LYS n 
1 241 GLY n 
1 242 GLN n 
1 243 PRO n 
1 244 GLY n 
1 245 TYR n 
1 246 VAL n 
1 247 PRO n 
1 248 GLU n 
1 249 TRP n 
1 250 GLN n 
1 251 ARG n 
1 252 PRO n 
1 253 HIS n 
1 254 LEU n 
1 255 SER n 
1 256 THR n 
1 257 LYS n 
1 258 ASN n 
1 259 LYS n 
1 260 ARG n 
1 261 ILE n 
1 262 ARG n 
1 263 LYS n 
1 264 TRP n 
1 265 TYR n 
1 266 ALA n 
1 267 ARG n 
1 268 ALA n 
1 269 ASN n 
1 270 TRP n 
1 271 ARG n 
1 272 ARG n 
1 273 LYS n 
1 274 PRO n 
1 275 GLY n 
1 276 ARG n 
1 277 LYS n 
1 278 SER n 
1 279 VAL n 
1 280 LEU n 
1 281 ASP n 
1 282 GLU n 
1 283 ALA n 
1 284 LYS n 
1 285 LEU n 
1 286 LYS n 
1 287 GLU n 
1 288 ALA n 
1 289 ALA n 
1 290 LEU n 
1 291 LYS n 
1 292 GLU n 
1 293 ALA n 
1 294 ILE n 
1 295 PRO n 
1 296 ILE n 
1 297 ILE n 
1 298 VAL n 
1 299 THR n 
1 300 ILE n 
1 301 GLY n 
1 302 LYS n 
1 303 ASP n 
1 304 TRP n 
1 305 ILE n 
1 306 VAL n 
1 307 MET n 
1 308 ASP n 
1 309 ALA n 
1 310 ARG n 
1 311 GLY n 
1 312 LEU n 
1 313 LEU n 
1 314 ARG n 
1 315 ALA n 
1 316 VAL n 
1 317 TYR n 
1 318 TRP n 
1 319 ARG n 
1 320 GLY n 
1 321 ILE n 
1 322 ALA n 
1 323 LYS n 
1 324 PRO n 
1 325 GLY n 
1 326 LEU n 
1 327 SER n 
1 328 LEU n 
1 329 LYS n 
1 330 GLU n 
1 331 LEU n 
1 332 LEU n 
1 333 GLY n 
1 334 PHE n 
1 335 PHE n 
1 336 SER n 
1 337 GLY n 
1 338 ASP n 
1 339 PRO n 
1 340 VAL n 
1 341 LEU n 
1 342 ASP n 
1 343 PRO n 
1 344 LYS n 
1 345 ARG n 
1 346 GLY n 
1 347 ILE n 
1 348 ALA n 
1 349 THR n 
1 350 PHE n 
1 351 THR n 
1 352 PHE n 
1 353 LYS n 
1 354 LEU n 
1 355 GLY n 
1 356 ALA n 
1 357 VAL n 
1 358 ALA n 
1 359 VAL n 
1 360 HIS n 
1 361 SER n 
1 362 ARG n 
1 363 LYS n 
1 364 PRO n 
1 365 THR n 
1 366 ARG n 
1 367 GLY n 
1 368 LYS n 
1 369 LYS n 
1 370 SER n 
1 371 LYS n 
1 372 GLU n 
1 373 LEU n 
1 374 LEU n 
1 375 LEU n 
1 376 SER n 
1 377 MET n 
1 378 THR n 
1 379 ALA n 
1 380 GLU n 
1 381 LYS n 
1 382 PRO n 
1 383 HIS n 
1 384 VAL n 
1 385 GLY n 
1 386 LEU n 
1 387 VAL n 
1 388 ALA n 
1 389 ILE n 
1 390 ASP n 
1 391 LEU n 
1 392 GLY n 
1 393 GLN n 
1 394 THR n 
1 395 ASN n 
1 396 PRO n 
1 397 VAL n 
1 398 ALA n 
1 399 ALA n 
1 400 GLU n 
1 401 PHE n 
1 402 SER n 
1 403 ARG n 
1 404 VAL n 
1 405 LYS n 
1 406 ARG n 
1 407 GLU n 
1 408 GLY n 
1 409 GLU n 
1 410 THR n 
1 411 LEU n 
1 412 GLN n 
1 413 ALA n 
1 414 GLU n 
1 415 PRO n 
1 416 LEU n 
1 417 GLY n 
1 418 GLN n 
1 419 ILE n 
1 420 VAL n 
1 421 LEU n 
1 422 PRO n 
1 423 ASP n 
1 424 ASP n 
1 425 LEU n 
1 426 VAL n 
1 427 LYS n 
1 428 ASP n 
1 429 LEU n 
1 430 THR n 
1 431 ARG n 
1 432 TYR n 
1 433 ARG n 
1 434 ARG n 
1 435 ALA n 
1 436 TRP n 
1 437 ASP n 
1 438 ALA n 
1 439 THR n 
1 440 GLU n 
1 441 GLU n 
1 442 GLN n 
1 443 ILE n 
1 444 LYS n 
1 445 ALA n 
1 446 GLU n 
1 447 ALA n 
1 448 ILE n 
1 449 VAL n 
1 450 GLN n 
1 451 LEU n 
1 452 PRO n 
1 453 GLU n 
1 454 GLU n 
1 455 CYS n 
1 456 ARG n 
1 457 ALA n 
1 458 GLU n 
1 459 VAL n 
1 460 VAL n 
1 461 LYS n 
1 462 VAL n 
1 463 ASN n 
1 464 GLN n 
1 465 MET n 
1 466 SER n 
1 467 ALA n 
1 468 GLU n 
1 469 GLU n 
1 470 THR n 
1 471 LYS n 
1 472 HIS n 
1 473 LEU n 
1 474 ILE n 
1 475 LEU n 
1 476 ASP n 
1 477 ARG n 
1 478 GLY n 
1 479 VAL n 
1 480 SER n 
1 481 GLY n 
1 482 ASP n 
1 483 LEU n 
1 484 PRO n 
1 485 TRP n 
1 486 GLU n 
1 487 LYS n 
1 488 MET n 
1 489 THR n 
1 490 SER n 
1 491 ASN n 
1 492 THR n 
1 493 THR n 
1 494 PHE n 
1 495 ILE n 
1 496 SER n 
1 497 ASP n 
1 498 HIS n 
1 499 LEU n 
1 500 LEU n 
1 501 ALA n 
1 502 LYS n 
1 503 GLY n 
1 504 VAL n 
1 505 THR n 
1 506 ASP n 
1 507 GLN n 
1 508 VAL n 
1 509 PHE n 
1 510 PHE n 
1 511 GLU n 
1 512 LYS n 
1 513 LYS n 
1 514 SER n 
1 515 LYS n 
1 516 GLY n 
1 517 LYS n 
1 518 LYS n 
1 519 LYS n 
1 520 GLY n 
1 521 THR n 
1 522 GLU n 
1 523 THR n 
1 524 VAL n 
1 525 LYS n 
1 526 ARG n 
1 527 LYS n 
1 528 ASP n 
1 529 TYR n 
1 530 GLY n 
1 531 TRP n 
1 532 VAL n 
1 533 LYS n 
1 534 LEU n 
1 535 LEU n 
1 536 ARG n 
1 537 PRO n 
1 538 ARG n 
1 539 LEU n 
1 540 SER n 
1 541 GLN n 
1 542 GLU n 
1 543 THR n 
1 544 ARG n 
1 545 LYS n 
1 546 ALA n 
1 547 VAL n 
1 548 ASN n 
1 549 ASP n 
1 550 LYS n 
1 551 THR n 
1 552 TRP n 
1 553 GLU n 
1 554 LEU n 
1 555 LYS n 
1 556 ARG n 
1 557 ALA n 
1 558 SER n 
1 559 THR n 
1 560 GLU n 
1 561 TYR n 
1 562 VAL n 
1 563 ARG n 
1 564 LEU n 
1 565 SER n 
1 566 ARG n 
1 567 ARG n 
1 568 LYS n 
1 569 THR n 
1 570 GLU n 
1 571 LEU n 
1 572 ALA n 
1 573 ARG n 
1 574 ARG n 
1 575 CYS n 
1 576 VAL n 
1 577 ASN n 
1 578 TYR n 
1 579 ILE n 
1 580 VAL n 
1 581 ARG n 
1 582 GLU n 
1 583 THR n 
1 584 LYS n 
1 585 ARG n 
1 586 TRP n 
1 587 THR n 
1 588 GLN n 
1 589 CYS n 
1 590 GLU n 
1 591 ASP n 
1 592 ILE n 
1 593 ALA n 
1 594 ILE n 
1 595 VAL n 
1 596 ILE n 
1 597 GLU n 
1 598 ASP n 
1 599 LEU n 
1 600 ASN n 
1 601 VAL n 
1 602 ARG n 
1 603 PHE n 
1 604 PHE n 
1 605 HIS n 
1 606 GLY n 
1 607 SER n 
1 608 GLY n 
1 609 GLU n 
1 610 ARG n 
1 611 PRO n 
1 612 ASP n 
1 613 GLY n 
1 614 TRP n 
1 615 ASP n 
1 616 ASN n 
1 617 PHE n 
1 618 PHE n 
1 619 ILE n 
1 620 SER n 
1 621 LYS n 
1 622 ARG n 
1 623 GLU n 
1 624 ASN n 
1 625 ARG n 
1 626 TRP n 
1 627 PHE n 
1 628 ILE n 
1 629 GLN n 
1 630 VAL n 
1 631 LEU n 
1 632 HIS n 
1 633 LYS n 
1 634 ALA n 
1 635 PHE n 
1 636 SER n 
1 637 ASP n 
1 638 LEU n 
1 639 ALA n 
1 640 LEU n 
1 641 HIS n 
1 642 ARG n 
1 643 GLY n 
1 644 LEU n 
1 645 PRO n 
1 646 VAL n 
1 647 ILE n 
1 648 GLU n 
1 649 ALA n 
1 650 ASN n 
1 651 PRO n 
1 652 ALA n 
1 653 ARG n 
1 654 THR n 
1 655 SER n 
1 656 ILE n 
1 657 THR n 
1 658 CYS n 
1 659 ILE n 
1 660 ARG n 
1 661 CYS n 
1 662 GLY n 
1 663 HIS n 
1 664 CYS n 
1 665 ASP n 
1 666 ARG n 
1 667 ASN n 
1 668 ASN n 
1 669 ARG n 
1 670 HIS n 
1 671 GLY n 
1 672 GLU n 
1 673 MET n 
1 674 PHE n 
1 675 LEU n 
1 676 CYS n 
1 677 LEU n 
1 678 SER n 
1 679 CYS n 
1 680 ASN n 
1 681 ASP n 
1 682 LEU n 
1 683 ARG n 
1 684 HIS n 
1 685 ALA n 
1 686 ASP n 
1 687 ARG n 
1 688 GLU n 
1 689 ILE n 
1 690 ALA n 
1 691 THR n 
1 692 ARG n 
1 693 ASN n 
1 694 LEU n 
1 695 THR n 
1 696 ARG n 
1 697 VAL n 
1 698 ALA n 
1 699 VAL n 
1 700 THR n 
1 701 GLY n 
1 702 GLU n 
1 703 MET n 
1 704 ILE n 
1 705 PRO n 
1 706 ARG n 
1 707 ARG n 
1 708 ILE n 
1 709 GLU n 
1 710 PRO n 
1 711 GLY n 
1 712 GLU n 
1 713 GLN n 
1 714 SER n 
1 715 GLY n 
1 716 ASP n 
1 717 THR n 
1 718 LYS n 
1 719 LYS n 
1 720 ALA n 
1 721 ARG n 
1 722 SER n 
1 723 ALA n 
1 724 ARG n 
1 725 LYS n 
1 726 GLY n 
1 727 LYS n 
1 728 LYS n 
1 729 ALA n 
1 730 VAL n 
1 731 ILE n 
1 732 SER n 
1 733 LYS n 
1 734 ARG n 
1 735 GLU n 
1 736 ALA n 
1 737 ALA n 
2 1   U   n 
2 2   C   n 
2 3   A   n 
2 4   A   n 
2 5   C   n 
2 6   G   n 
2 7   C   n 
2 8   U   n 
2 9   U   n 
2 10  G   n 
2 11  C   n 
2 12  U   n 
2 13  C   n 
2 14  G   n 
2 15  G   n 
2 16  U   n 
2 17  U   n 
2 18  C   n 
2 19  G   n 
2 20  C   n 
2 21  C   n 
2 22  G   n 
2 23  A   n 
2 24  G   n 
2 25  A   n 
2 26  C   n 
2 27  U   n 
2 28  C   n 
2 29  C   n 
2 30  C   n 
2 31  C   n 
2 32  U   n 
2 33  A   n 
2 34  C   n 
2 35  G   n 
2 36  U   n 
2 37  G   n 
2 38  C   n 
2 39  U   n 
2 40  G   n 
2 41  C   n 
2 42  U   n 
2 43  G   n 
2 44  A   n 
2 45  A   n 
2 46  G   n 
3 1   DC  n 
3 2   DT  n 
3 3   DG  n 
3 4   DC  n 
3 5   DC  n 
3 6   DC  n 
3 7   DT  n 
3 8   DT  n 
3 9   DG  n 
3 10  DC  n 
3 11  DA  n 
3 12  DA  n 
3 13  DG  n 
3 14  DA  n 
3 15  DA  n 
3 16  DG  n 
3 17  DT  n 
3 18  DC  n 
3 19  DG  n 
3 20  DT  n 
3 21  DC  n 
3 22  DG  n 
3 23  DT  n 
3 24  DG  n 
3 25  DC  n 
3 26  DA  n 
3 27  DT  n 
3 28  DG  n 
3 29  DG  n 
3 30  DG  n 
3 31  DG  n 
3 32  DA  n 
3 33  DG  n 
3 34  DA  n 
3 35  DA  n 
3 36  DT  n 
3 37  DT  n 
3 38  DG  n 
3 39  DG  n 
3 40  DC  n 
3 41  DC  n 
3 42  DA  n 
4 1   DT  n 
4 2   DG  n 
4 3   DG  n 
4 4   DC  n 
4 5   DC  n 
4 6   DA  n 
4 7   DA  n 
4 8   DT  n 
4 9   DT  n 
4 10  DC  n 
4 11  DT  n 
4 12  DC  n 
4 13  DC  n 
4 14  DC  n 
4 15  DC  n 
4 16  DA  n 
4 17  DT  n 
4 18  DG  n 
4 19  DC  n 
4 20  DA  n 
4 21  DC  n 
4 22  DG  n 
4 23  DA  n 
4 24  DC  n 
4 25  DG  n 
4 26  DA  n 
4 27  DC  n 
4 28  DT  n 
4 29  DT  n 
4 30  DC  n 
4 31  DT  n 
4 32  DT  n 
4 33  DG  n 
4 34  DC  n 
4 35  DA  n 
4 36  DA  n 
4 37  DG  n 
4 38  DG  n 
4 39  DG  n 
4 40  DC  n 
4 41  DA  n 
4 42  DG  n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 737 ? ? ? ? ? ? ? ? ? 'unclassified sequences' 12908 ? ? ? ? ? ? ? ? 
'Escherichia coli BL21(DE3)' 469008 ? ? ? ? ? ? ? ? 'BL21(DE3)' ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 46  ? ? ? ? ? ? ? ? ? 'unclassified sequences' 12908 ? ? ? ? ? ? ? ? 'unclassified sequences' 
12908  ? ? ? ? ? ? ? ? ?           ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 42  ? ? ? ? ? ? ? ? ? 'unclassified sequences' 12908 ? ? ? ? ? ? ? ? 'unclassified sequences' 
12908  ? ? ? ? ? ? ? ? ?           ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 'Biological sequence' 1 42  ? ? ? ? ? ? ? ? ? 'unclassified sequences' 12908 ? ? ? ? ? ? ? ? 'unclassified sequences' 
12908  ? ? ? ? ? ? ? ? ?           ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A   'RNA linking'       y "ADENOSINE-5'-MONOPHOSPHATE"         ? 'C10 H14 N5 O7 P' 347.221 
ALA 'L-peptide linking' y ALANINE                              ? 'C3 H7 N O2'      89.093  
ARG 'L-peptide linking' y ARGININE                             ? 'C6 H15 N4 O2 1'  175.209 
ASN 'L-peptide linking' y ASPARAGINE                           ? 'C4 H8 N2 O3'     132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                      ? 'C4 H7 N O4'      133.103 
C   'RNA linking'       y "CYTIDINE-5'-MONOPHOSPHATE"          ? 'C9 H14 N3 O8 P'  323.197 
CYS 'L-peptide linking' y CYSTEINE                             ? 'C3 H7 N O2 S'    121.158 
DA  'DNA linking'       y "2'-DEOXYADENOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O6 P' 331.222 
DC  'DNA linking'       y "2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE"  ? 'C9 H14 N3 O7 P'  307.197 
DG  'DNA linking'       y "2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O7 P' 347.221 
DT  'DNA linking'       y "THYMIDINE-5'-MONOPHOSPHATE"         ? 'C10 H15 N2 O8 P' 322.208 
G   'RNA linking'       y "GUANOSINE-5'-MONOPHOSPHATE"         ? 'C10 H14 N5 O8 P' 363.221 
GLN 'L-peptide linking' y GLUTAMINE                            ? 'C5 H10 N2 O3'    146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                      ? 'C5 H9 N O4'      147.129 
GLY 'peptide linking'   y GLYCINE                              ? 'C2 H5 N O2'      75.067  
HIS 'L-peptide linking' y HISTIDINE                            ? 'C6 H10 N3 O2 1'  156.162 
ILE 'L-peptide linking' y ISOLEUCINE                           ? 'C6 H13 N O2'     131.173 
LEU 'L-peptide linking' y LEUCINE                              ? 'C6 H13 N O2'     131.173 
LYS 'L-peptide linking' y LYSINE                               ? 'C6 H15 N2 O2 1'  147.195 
MET 'L-peptide linking' y METHIONINE                           ? 'C5 H11 N O2 S'   149.211 
PHE 'L-peptide linking' y PHENYLALANINE                        ? 'C9 H11 N O2'     165.189 
PRO 'L-peptide linking' y PROLINE                              ? 'C5 H9 N O2'      115.130 
SER 'L-peptide linking' y SERINE                               ? 'C3 H7 N O3'      105.093 
THR 'L-peptide linking' y THREONINE                            ? 'C4 H9 N O3'      119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                           ? 'C11 H12 N2 O2'   204.225 
TYR 'L-peptide linking' y TYROSINE                             ? 'C9 H11 N O3'     181.189 
U   'RNA linking'       y "URIDINE-5'-MONOPHOSPHATE"           ? 'C9 H13 N2 O9 P'  324.181 
VAL 'L-peptide linking' y VALINE                               ? 'C5 H11 N O2'     117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   THR 2   2   ?   ?   ?   A . n 
A 1 3   PRO 3   3   ?   ?   ?   A . n 
A 1 4   LYS 4   4   ?   ?   ?   A . n 
A 1 5   THR 5   5   ?   ?   ?   A . n 
A 1 6   GLU 6   6   ?   ?   ?   A . n 
A 1 7   THR 7   7   ?   ?   ?   A . n 
A 1 8   PRO 8   8   ?   ?   ?   A . n 
A 1 9   VAL 9   9   ?   ?   ?   A . n 
A 1 10  GLY 10  10  ?   ?   ?   A . n 
A 1 11  ALA 11  11  ?   ?   ?   A . n 
A 1 12  LEU 12  12  ?   ?   ?   A . n 
A 1 13  ILE 13  13  ?   ?   ?   A . n 
A 1 14  LYS 14  14  ?   ?   ?   A . n 
A 1 15  LYS 15  15  ?   ?   ?   A . n 
A 1 16  PHE 16  16  ?   ?   ?   A . n 
A 1 17  PHE 17  17  ?   ?   ?   A . n 
A 1 18  PRO 18  18  ?   ?   ?   A . n 
A 1 19  GLY 19  19  ?   ?   ?   A . n 
A 1 20  LYS 20  20  ?   ?   ?   A . n 
A 1 21  ARG 21  21  ?   ?   ?   A . n 
A 1 22  PHE 22  22  ?   ?   ?   A . n 
A 1 23  GLN 23  23  ?   ?   ?   A . n 
A 1 24  LYS 24  24  ?   ?   ?   A . n 
A 1 25  ASN 25  25  ?   ?   ?   A . n 
A 1 26  TYR 26  26  ?   ?   ?   A . n 
A 1 27  LEU 27  27  ?   ?   ?   A . n 
A 1 28  LYS 28  28  ?   ?   ?   A . n 
A 1 29  ASP 29  29  ?   ?   ?   A . n 
A 1 30  ALA 30  30  ?   ?   ?   A . n 
A 1 31  GLY 31  31  ?   ?   ?   A . n 
A 1 32  LYS 32  32  ?   ?   ?   A . n 
A 1 33  LYS 33  33  ?   ?   ?   A . n 
A 1 34  LEU 34  34  ?   ?   ?   A . n 
A 1 35  LYS 35  35  ?   ?   ?   A . n 
A 1 36  ARG 36  36  ?   ?   ?   A . n 
A 1 37  GLU 37  37  ?   ?   ?   A . n 
A 1 38  GLY 38  38  ?   ?   ?   A . n 
A 1 39  GLU 39  39  ?   ?   ?   A . n 
A 1 40  ALA 40  40  ?   ?   ?   A . n 
A 1 41  ALA 41  41  ?   ?   ?   A . n 
A 1 42  ALA 42  42  ?   ?   ?   A . n 
A 1 43  VAL 43  43  ?   ?   ?   A . n 
A 1 44  GLU 44  44  ?   ?   ?   A . n 
A 1 45  TYR 45  45  ?   ?   ?   A . n 
A 1 46  LEU 46  46  ?   ?   ?   A . n 
A 1 47  SER 47  47  ?   ?   ?   A . n 
A 1 48  GLY 48  48  ?   ?   ?   A . n 
A 1 49  LYS 49  49  ?   ?   ?   A . n 
A 1 50  GLN 50  50  ?   ?   ?   A . n 
A 1 51  GLU 51  51  ?   ?   ?   A . n 
A 1 52  ASP 52  52  ?   ?   ?   A . n 
A 1 53  HIS 53  53  ?   ?   ?   A . n 
A 1 54  PRO 54  54  ?   ?   ?   A . n 
A 1 55  ALA 55  55  ?   ?   ?   A . n 
A 1 56  ASN 56  56  ?   ?   ?   A . n 
A 1 57  PHE 57  57  57  PHE PHE A . n 
A 1 58  CYS 58  58  58  CYS CYS A . n 
A 1 59  PRO 59  59  59  PRO PRO A . n 
A 1 60  PRO 60  60  60  PRO PRO A . n 
A 1 61  ALA 61  61  61  ALA ALA A . n 
A 1 62  LYS 62  62  62  LYS LYS A . n 
A 1 63  VAL 63  63  63  VAL VAL A . n 
A 1 64  ASN 64  64  64  ASN ASN A . n 
A 1 65  ILE 65  65  65  ILE ILE A . n 
A 1 66  LEU 66  66  66  LEU LEU A . n 
A 1 67  ALA 67  67  67  ALA ALA A . n 
A 1 68  GLN 68  68  68  GLN GLN A . n 
A 1 69  SER 69  69  69  SER SER A . n 
A 1 70  ARG 70  70  70  ARG ARG A . n 
A 1 71  PRO 71  71  71  PRO PRO A . n 
A 1 72  LEU 72  72  72  LEU LEU A . n 
A 1 73  SER 73  73  73  SER SER A . n 
A 1 74  GLU 74  74  74  GLU GLU A . n 
A 1 75  TRP 75  75  75  TRP TRP A . n 
A 1 76  PRO 76  76  76  PRO PRO A . n 
A 1 77  ILE 77  77  77  ILE ILE A . n 
A 1 78  ASN 78  78  78  ASN ASN A . n 
A 1 79  LEU 79  79  79  LEU LEU A . n 
A 1 80  VAL 80  80  80  VAL VAL A . n 
A 1 81  SER 81  81  81  SER SER A . n 
A 1 82  LYS 82  82  82  LYS LYS A . n 
A 1 83  GLY 83  83  83  GLY GLY A . n 
A 1 84  VAL 84  84  84  VAL VAL A . n 
A 1 85  GLN 85  85  85  GLN GLN A . n 
A 1 86  GLU 86  86  86  GLU GLU A . n 
A 1 87  TYR 87  87  87  TYR TYR A . n 
A 1 88  VAL 88  88  88  VAL VAL A . n 
A 1 89  TYR 89  89  ?   ?   ?   A . n 
A 1 90  GLY 90  90  ?   ?   ?   A . n 
A 1 91  LEU 91  91  ?   ?   ?   A . n 
A 1 92  THR 92  92  ?   ?   ?   A . n 
A 1 93  ALA 93  93  ?   ?   ?   A . n 
A 1 94  ALA 94  94  ?   ?   ?   A . n 
A 1 95  GLU 95  95  ?   ?   ?   A . n 
A 1 96  ARG 96  96  ?   ?   ?   A . n 
A 1 97  GLU 97  97  ?   ?   ?   A . n 
A 1 98  ALA 98  98  98  ALA ALA A . n 
A 1 99  ASN 99  99  99  ASN ASN A . n 
A 1 100 GLY 100 100 100 GLY GLY A . n 
A 1 101 ASP 101 101 101 ASP ASP A . n 
A 1 102 PHE 102 102 102 PHE PHE A . n 
A 1 103 GLY 103 103 103 GLY GLY A . n 
A 1 104 THR 104 104 104 THR THR A . n 
A 1 105 SER 105 105 105 SER SER A . n 
A 1 106 ARG 106 106 106 ARG ARG A . n 
A 1 107 LYS 107 107 107 LYS LYS A . n 
A 1 108 SER 108 108 108 SER SER A . n 
A 1 109 LEU 109 109 109 LEU LEU A . n 
A 1 110 ASP 110 110 110 ASP ASP A . n 
A 1 111 ARG 111 111 111 ARG ARG A . n 
A 1 112 TRP 112 112 112 TRP TRP A . n 
A 1 113 PHE 113 113 113 PHE PHE A . n 
A 1 114 ALA 114 114 114 ALA ALA A . n 
A 1 115 ARG 115 115 115 ARG ARG A . n 
A 1 116 THR 116 116 116 THR THR A . n 
A 1 117 GLY 117 117 117 GLY GLY A . n 
A 1 118 VAL 118 118 118 VAL VAL A . n 
A 1 119 PRO 119 119 119 PRO PRO A . n 
A 1 120 THR 120 120 120 THR THR A . n 
A 1 121 HIS 121 121 121 HIS HIS A . n 
A 1 122 GLY 122 122 122 GLY GLY A . n 
A 1 123 TYR 123 123 123 TYR TYR A . n 
A 1 124 THR 124 124 124 THR THR A . n 
A 1 125 THR 125 125 125 THR THR A . n 
A 1 126 VAL 126 126 126 VAL VAL A . n 
A 1 127 GLN 127 127 127 GLN GLN A . n 
A 1 128 GLY 128 128 128 GLY GLY A . n 
A 1 129 LEU 129 129 129 LEU LEU A . n 
A 1 130 ASN 130 130 130 ASN ASN A . n 
A 1 131 LEU 131 131 131 LEU LEU A . n 
A 1 132 ILE 132 132 132 ILE ILE A . n 
A 1 133 LEU 133 133 133 LEU LEU A . n 
A 1 134 ARG 134 134 134 ARG ARG A . n 
A 1 135 HIS 135 135 135 HIS HIS A . n 
A 1 136 THR 136 136 136 THR THR A . n 
A 1 137 PHE 137 137 137 PHE PHE A . n 
A 1 138 ASN 138 138 138 ASN ASN A . n 
A 1 139 ARG 139 139 139 ARG ARG A . n 
A 1 140 TYR 140 140 140 TYR TYR A . n 
A 1 141 ASP 141 141 141 ASP ASP A . n 
A 1 142 GLY 142 142 142 GLY GLY A . n 
A 1 143 VAL 143 143 143 VAL VAL A . n 
A 1 144 ILE 144 144 144 ILE ILE A . n 
A 1 145 LYS 145 145 145 LYS LYS A . n 
A 1 146 LYS 146 146 146 LYS LYS A . n 
A 1 147 VAL 147 147 147 VAL VAL A . n 
A 1 148 GLU 148 148 148 GLU GLU A . n 
A 1 149 THR 149 149 149 THR THR A . n 
A 1 150 ARG 150 150 150 ARG ARG A . n 
A 1 151 ASN 151 151 151 ASN ASN A . n 
A 1 152 GLU 152 152 ?   ?   ?   A . n 
A 1 153 LYS 153 153 ?   ?   ?   A . n 
A 1 154 ARG 154 154 ?   ?   ?   A . n 
A 1 155 ARG 155 155 ?   ?   ?   A . n 
A 1 156 SER 156 156 ?   ?   ?   A . n 
A 1 157 LYS 157 157 ?   ?   ?   A . n 
A 1 158 ALA 158 158 ?   ?   ?   A . n 
A 1 159 THR 159 159 ?   ?   ?   A . n 
A 1 160 ARG 160 160 ?   ?   ?   A . n 
A 1 161 ILE 161 161 ?   ?   ?   A . n 
A 1 162 ASN 162 162 ?   ?   ?   A . n 
A 1 163 VAL 163 163 ?   ?   ?   A . n 
A 1 164 SER 164 164 ?   ?   ?   A . n 
A 1 165 ARG 165 165 ?   ?   ?   A . n 
A 1 166 GLU 166 166 ?   ?   ?   A . n 
A 1 167 ALA 167 167 ?   ?   ?   A . n 
A 1 168 ASP 168 168 ?   ?   ?   A . n 
A 1 169 GLY 169 169 ?   ?   ?   A . n 
A 1 170 LEU 170 170 ?   ?   ?   A . n 
A 1 171 PRO 171 171 ?   ?   ?   A . n 
A 1 172 PRO 172 172 ?   ?   ?   A . n 
A 1 173 ILE 173 173 ?   ?   ?   A . n 
A 1 174 GLU 174 174 ?   ?   ?   A . n 
A 1 175 ALA 175 175 ?   ?   ?   A . n 
A 1 176 GLU 176 176 ?   ?   ?   A . n 
A 1 177 PRO 177 177 ?   ?   ?   A . n 
A 1 178 GLU 178 178 ?   ?   ?   A . n 
A 1 179 GLU 179 179 ?   ?   ?   A . n 
A 1 180 THR 180 180 ?   ?   ?   A . n 
A 1 181 ALA 181 181 ?   ?   ?   A . n 
A 1 182 PHE 182 182 ?   ?   ?   A . n 
A 1 183 GLY 183 183 ?   ?   ?   A . n 
A 1 184 PRO 184 184 ?   ?   ?   A . n 
A 1 185 ASP 185 185 ?   ?   ?   A . n 
A 1 186 GLY 186 186 ?   ?   ?   A . n 
A 1 187 LYS 187 187 ?   ?   ?   A . n 
A 1 188 LEU 188 188 ?   ?   ?   A . n 
A 1 189 LYS 189 189 ?   ?   ?   A . n 
A 1 190 GLU 190 190 ?   ?   ?   A . n 
A 1 191 ARG 191 191 ?   ?   ?   A . n 
A 1 192 PRO 192 192 192 PRO PRO A . n 
A 1 193 GLY 193 193 193 GLY GLY A . n 
A 1 194 ILE 194 194 194 ILE ILE A . n 
A 1 195 ASN 195 195 195 ASN ASN A . n 
A 1 196 PRO 196 196 196 PRO PRO A . n 
A 1 197 SER 197 197 197 SER SER A . n 
A 1 198 ILE 198 198 198 ILE ILE A . n 
A 1 199 TYR 199 199 199 TYR TYR A . n 
A 1 200 CYS 200 200 200 CYS CYS A . n 
A 1 201 TYR 201 201 201 TYR TYR A . n 
A 1 202 GLN 202 202 202 GLN GLN A . n 
A 1 203 GLN 203 203 203 GLN GLN A . n 
A 1 204 VAL 204 204 204 VAL VAL A . n 
A 1 205 SER 205 205 205 SER SER A . n 
A 1 206 PRO 206 206 206 PRO PRO A . n 
A 1 207 VAL 207 207 207 VAL VAL A . n 
A 1 208 PRO 208 208 208 PRO PRO A . n 
A 1 209 TYR 209 209 209 TYR TYR A . n 
A 1 210 ASN 210 210 210 ASN ASN A . n 
A 1 211 PRO 211 211 211 PRO PRO A . n 
A 1 212 ALA 212 212 ?   ?   ?   A . n 
A 1 213 LYS 213 213 ?   ?   ?   A . n 
A 1 214 HIS 214 214 ?   ?   ?   A . n 
A 1 215 PRO 215 215 ?   ?   ?   A . n 
A 1 216 ALA 216 216 ?   ?   ?   A . n 
A 1 217 LEU 217 217 ?   ?   ?   A . n 
A 1 218 PRO 218 218 ?   ?   ?   A . n 
A 1 219 PHE 219 219 ?   ?   ?   A . n 
A 1 220 SER 220 220 ?   ?   ?   A . n 
A 1 221 GLY 221 221 ?   ?   ?   A . n 
A 1 222 VAL 222 222 ?   ?   ?   A . n 
A 1 223 ASP 223 223 ?   ?   ?   A . n 
A 1 224 PRO 224 224 ?   ?   ?   A . n 
A 1 225 GLY 225 225 ?   ?   ?   A . n 
A 1 226 ALA 226 226 ?   ?   ?   A . n 
A 1 227 PRO 227 227 ?   ?   ?   A . n 
A 1 228 LEU 228 228 228 LEU LEU A . n 
A 1 229 PRO 229 229 229 PRO PRO A . n 
A 1 230 LEU 230 230 230 LEU LEU A . n 
A 1 231 GLY 231 231 231 GLY GLY A . n 
A 1 232 THR 232 232 232 THR THR A . n 
A 1 233 PRO 233 233 233 PRO PRO A . n 
A 1 234 ASN 234 234 234 ASN ASN A . n 
A 1 235 ARG 235 235 235 ARG ARG A . n 
A 1 236 LEU 236 236 236 LEU LEU A . n 
A 1 237 SER 237 237 237 SER SER A . n 
A 1 238 ILE 238 238 238 ILE ILE A . n 
A 1 239 PRO 239 239 239 PRO PRO A . n 
A 1 240 LYS 240 240 240 LYS LYS A . n 
A 1 241 GLY 241 241 241 GLY GLY A . n 
A 1 242 GLN 242 242 242 GLN GLN A . n 
A 1 243 PRO 243 243 243 PRO PRO A . n 
A 1 244 GLY 244 244 244 GLY GLY A . n 
A 1 245 TYR 245 245 245 TYR TYR A . n 
A 1 246 VAL 246 246 246 VAL VAL A . n 
A 1 247 PRO 247 247 247 PRO PRO A . n 
A 1 248 GLU 248 248 248 GLU GLU A . n 
A 1 249 TRP 249 249 249 TRP TRP A . n 
A 1 250 GLN 250 250 250 GLN GLN A . n 
A 1 251 ARG 251 251 251 ARG ARG A . n 
A 1 252 PRO 252 252 252 PRO PRO A . n 
A 1 253 HIS 253 253 253 HIS HIS A . n 
A 1 254 LEU 254 254 254 LEU LEU A . n 
A 1 255 SER 255 255 255 SER SER A . n 
A 1 256 THR 256 256 256 THR THR A . n 
A 1 257 LYS 257 257 257 LYS LYS A . n 
A 1 258 ASN 258 258 258 ASN ASN A . n 
A 1 259 LYS 259 259 259 LYS LYS A . n 
A 1 260 ARG 260 260 260 ARG ARG A . n 
A 1 261 ILE 261 261 261 ILE ILE A . n 
A 1 262 ARG 262 262 262 ARG ARG A . n 
A 1 263 LYS 263 263 263 LYS LYS A . n 
A 1 264 TRP 264 264 264 TRP TRP A . n 
A 1 265 TYR 265 265 265 TYR TYR A . n 
A 1 266 ALA 266 266 266 ALA ALA A . n 
A 1 267 ARG 267 267 267 ARG ARG A . n 
A 1 268 ALA 268 268 268 ALA ALA A . n 
A 1 269 ASN 269 269 269 ASN ASN A . n 
A 1 270 TRP 270 270 270 TRP TRP A . n 
A 1 271 ARG 271 271 271 ARG ARG A . n 
A 1 272 ARG 272 272 272 ARG ARG A . n 
A 1 273 LYS 273 273 273 LYS LYS A . n 
A 1 274 PRO 274 274 274 PRO PRO A . n 
A 1 275 GLY 275 275 275 GLY GLY A . n 
A 1 276 ARG 276 276 276 ARG ARG A . n 
A 1 277 LYS 277 277 277 LYS LYS A . n 
A 1 278 SER 278 278 278 SER SER A . n 
A 1 279 VAL 279 279 279 VAL VAL A . n 
A 1 280 LEU 280 280 280 LEU LEU A . n 
A 1 281 ASP 281 281 281 ASP ASP A . n 
A 1 282 GLU 282 282 282 GLU GLU A . n 
A 1 283 ALA 283 283 283 ALA ALA A . n 
A 1 284 LYS 284 284 284 LYS LYS A . n 
A 1 285 LEU 285 285 285 LEU LEU A . n 
A 1 286 LYS 286 286 286 LYS LYS A . n 
A 1 287 GLU 287 287 287 GLU GLU A . n 
A 1 288 ALA 288 288 288 ALA ALA A . n 
A 1 289 ALA 289 289 289 ALA ALA A . n 
A 1 290 LEU 290 290 290 LEU LEU A . n 
A 1 291 LYS 291 291 291 LYS LYS A . n 
A 1 292 GLU 292 292 292 GLU GLU A . n 
A 1 293 ALA 293 293 293 ALA ALA A . n 
A 1 294 ILE 294 294 294 ILE ILE A . n 
A 1 295 PRO 295 295 295 PRO PRO A . n 
A 1 296 ILE 296 296 296 ILE ILE A . n 
A 1 297 ILE 297 297 297 ILE ILE A . n 
A 1 298 VAL 298 298 298 VAL VAL A . n 
A 1 299 THR 299 299 299 THR THR A . n 
A 1 300 ILE 300 300 300 ILE ILE A . n 
A 1 301 GLY 301 301 301 GLY GLY A . n 
A 1 302 LYS 302 302 302 LYS LYS A . n 
A 1 303 ASP 303 303 303 ASP ASP A . n 
A 1 304 TRP 304 304 304 TRP TRP A . n 
A 1 305 ILE 305 305 305 ILE ILE A . n 
A 1 306 VAL 306 306 306 VAL VAL A . n 
A 1 307 MET 307 307 307 MET MET A . n 
A 1 308 ASP 308 308 308 ASP ASP A . n 
A 1 309 ALA 309 309 309 ALA ALA A . n 
A 1 310 ARG 310 310 310 ARG ARG A . n 
A 1 311 GLY 311 311 311 GLY GLY A . n 
A 1 312 LEU 312 312 312 LEU LEU A . n 
A 1 313 LEU 313 313 313 LEU LEU A . n 
A 1 314 ARG 314 314 314 ARG ARG A . n 
A 1 315 ALA 315 315 315 ALA ALA A . n 
A 1 316 VAL 316 316 316 VAL VAL A . n 
A 1 317 TYR 317 317 317 TYR TYR A . n 
A 1 318 TRP 318 318 318 TRP TRP A . n 
A 1 319 ARG 319 319 319 ARG ARG A . n 
A 1 320 GLY 320 320 320 GLY GLY A . n 
A 1 321 ILE 321 321 321 ILE ILE A . n 
A 1 322 ALA 322 322 322 ALA ALA A . n 
A 1 323 LYS 323 323 323 LYS LYS A . n 
A 1 324 PRO 324 324 324 PRO GLY A . n 
A 1 325 GLY 325 325 325 GLY ALA A . n 
A 1 326 LEU 326 326 326 LEU LEU A . n 
A 1 327 SER 327 327 327 SER SER A . n 
A 1 328 LEU 328 328 328 LEU LEU A . n 
A 1 329 LYS 329 329 329 LYS LYS A . n 
A 1 330 GLU 330 330 330 GLU GLU A . n 
A 1 331 LEU 331 331 331 LEU LEU A . n 
A 1 332 LEU 332 332 332 LEU LEU A . n 
A 1 333 GLY 333 333 333 GLY GLY A . n 
A 1 334 PHE 334 334 334 PHE PHE A . n 
A 1 335 PHE 335 335 335 PHE PHE A . n 
A 1 336 SER 336 336 336 SER SER A . n 
A 1 337 GLY 337 337 337 GLY GLY A . n 
A 1 338 ASP 338 338 338 ASP ASP A . n 
A 1 339 PRO 339 339 339 PRO PRO A . n 
A 1 340 VAL 340 340 340 VAL VAL A . n 
A 1 341 LEU 341 341 341 LEU LEU A . n 
A 1 342 ASP 342 342 342 ASP ASP A . n 
A 1 343 PRO 343 343 343 PRO PRO A . n 
A 1 344 LYS 344 344 344 LYS LYS A . n 
A 1 345 ARG 345 345 345 ARG ARG A . n 
A 1 346 GLY 346 346 346 GLY GLY A . n 
A 1 347 ILE 347 347 347 ILE ILE A . n 
A 1 348 ALA 348 348 348 ALA ALA A . n 
A 1 349 THR 349 349 349 THR THR A . n 
A 1 350 PHE 350 350 350 PHE PHE A . n 
A 1 351 THR 351 351 351 THR THR A . n 
A 1 352 PHE 352 352 352 PHE PHE A . n 
A 1 353 LYS 353 353 353 LYS LYS A . n 
A 1 354 LEU 354 354 354 LEU LEU A . n 
A 1 355 GLY 355 355 355 GLY GLY A . n 
A 1 356 ALA 356 356 ?   ?   ?   A . n 
A 1 357 VAL 357 357 ?   ?   ?   A . n 
A 1 358 ALA 358 358 ?   ?   ?   A . n 
A 1 359 VAL 359 359 ?   ?   ?   A . n 
A 1 360 HIS 360 360 ?   ?   ?   A . n 
A 1 361 SER 361 361 ?   ?   ?   A . n 
A 1 362 ARG 362 362 ?   ?   ?   A . n 
A 1 363 LYS 363 363 ?   ?   ?   A . n 
A 1 364 PRO 364 364 ?   ?   ?   A . n 
A 1 365 THR 365 365 ?   ?   ?   A . n 
A 1 366 ARG 366 366 ?   ?   ?   A . n 
A 1 367 GLY 367 367 ?   ?   ?   A . n 
A 1 368 LYS 368 368 ?   ?   ?   A . n 
A 1 369 LYS 369 369 ?   ?   ?   A . n 
A 1 370 SER 370 370 ?   ?   ?   A . n 
A 1 371 LYS 371 371 ?   ?   ?   A . n 
A 1 372 GLU 372 372 ?   ?   ?   A . n 
A 1 373 LEU 373 373 ?   ?   ?   A . n 
A 1 374 LEU 374 374 ?   ?   ?   A . n 
A 1 375 LEU 375 375 ?   ?   ?   A . n 
A 1 376 SER 376 376 ?   ?   ?   A . n 
A 1 377 MET 377 377 ?   ?   ?   A . n 
A 1 378 THR 378 378 ?   ?   ?   A . n 
A 1 379 ALA 379 379 ?   ?   ?   A . n 
A 1 380 GLU 380 380 ?   ?   ?   A . n 
A 1 381 LYS 381 381 ?   ?   ?   A . n 
A 1 382 PRO 382 382 ?   ?   ?   A . n 
A 1 383 HIS 383 383 ?   ?   ?   A . n 
A 1 384 VAL 384 384 ?   ?   ?   A . n 
A 1 385 GLY 385 385 ?   ?   ?   A . n 
A 1 386 LEU 386 386 ?   ?   ?   A . n 
A 1 387 VAL 387 387 ?   ?   ?   A . n 
A 1 388 ALA 388 388 ?   ?   ?   A . n 
A 1 389 ILE 389 389 ?   ?   ?   A . n 
A 1 390 ASP 390 390 ?   ?   ?   A . n 
A 1 391 LEU 391 391 ?   ?   ?   A . n 
A 1 392 GLY 392 392 ?   ?   ?   A . n 
A 1 393 GLN 393 393 ?   ?   ?   A . n 
A 1 394 THR 394 394 ?   ?   ?   A . n 
A 1 395 ASN 395 395 ?   ?   ?   A . n 
A 1 396 PRO 396 396 ?   ?   ?   A . n 
A 1 397 VAL 397 397 ?   ?   ?   A . n 
A 1 398 ALA 398 398 ?   ?   ?   A . n 
A 1 399 ALA 399 399 ?   ?   ?   A . n 
A 1 400 GLU 400 400 ?   ?   ?   A . n 
A 1 401 PHE 401 401 ?   ?   ?   A . n 
A 1 402 SER 402 402 ?   ?   ?   A . n 
A 1 403 ARG 403 403 ?   ?   ?   A . n 
A 1 404 VAL 404 404 ?   ?   ?   A . n 
A 1 405 LYS 405 405 ?   ?   ?   A . n 
A 1 406 ARG 406 406 ?   ?   ?   A . n 
A 1 407 GLU 407 407 ?   ?   ?   A . n 
A 1 408 GLY 408 408 ?   ?   ?   A . n 
A 1 409 GLU 409 409 ?   ?   ?   A . n 
A 1 410 THR 410 410 ?   ?   ?   A . n 
A 1 411 LEU 411 411 ?   ?   ?   A . n 
A 1 412 GLN 412 412 ?   ?   ?   A . n 
A 1 413 ALA 413 413 ?   ?   ?   A . n 
A 1 414 GLU 414 414 ?   ?   ?   A . n 
A 1 415 PRO 415 415 ?   ?   ?   A . n 
A 1 416 LEU 416 416 ?   ?   ?   A . n 
A 1 417 GLY 417 417 ?   ?   ?   A . n 
A 1 418 GLN 418 418 ?   ?   ?   A . n 
A 1 419 ILE 419 419 ?   ?   ?   A . n 
A 1 420 VAL 420 420 ?   ?   ?   A . n 
A 1 421 LEU 421 421 ?   ?   ?   A . n 
A 1 422 PRO 422 422 ?   ?   ?   A . n 
A 1 423 ASP 423 423 ?   ?   ?   A . n 
A 1 424 ASP 424 424 ?   ?   ?   A . n 
A 1 425 LEU 425 425 ?   ?   ?   A . n 
A 1 426 VAL 426 426 ?   ?   ?   A . n 
A 1 427 LYS 427 427 ?   ?   ?   A . n 
A 1 428 ASP 428 428 ?   ?   ?   A . n 
A 1 429 LEU 429 429 ?   ?   ?   A . n 
A 1 430 THR 430 430 ?   ?   ?   A . n 
A 1 431 ARG 431 431 ?   ?   ?   A . n 
A 1 432 TYR 432 432 ?   ?   ?   A . n 
A 1 433 ARG 433 433 ?   ?   ?   A . n 
A 1 434 ARG 434 434 ?   ?   ?   A . n 
A 1 435 ALA 435 435 ?   ?   ?   A . n 
A 1 436 TRP 436 436 ?   ?   ?   A . n 
A 1 437 ASP 437 437 ?   ?   ?   A . n 
A 1 438 ALA 438 438 ?   ?   ?   A . n 
A 1 439 THR 439 439 ?   ?   ?   A . n 
A 1 440 GLU 440 440 ?   ?   ?   A . n 
A 1 441 GLU 441 441 ?   ?   ?   A . n 
A 1 442 GLN 442 442 ?   ?   ?   A . n 
A 1 443 ILE 443 443 ?   ?   ?   A . n 
A 1 444 LYS 444 444 ?   ?   ?   A . n 
A 1 445 ALA 445 445 ?   ?   ?   A . n 
A 1 446 GLU 446 446 ?   ?   ?   A . n 
A 1 447 ALA 447 447 ?   ?   ?   A . n 
A 1 448 ILE 448 448 ?   ?   ?   A . n 
A 1 449 VAL 449 449 ?   ?   ?   A . n 
A 1 450 GLN 450 450 ?   ?   ?   A . n 
A 1 451 LEU 451 451 ?   ?   ?   A . n 
A 1 452 PRO 452 452 ?   ?   ?   A . n 
A 1 453 GLU 453 453 ?   ?   ?   A . n 
A 1 454 GLU 454 454 ?   ?   ?   A . n 
A 1 455 CYS 455 455 ?   ?   ?   A . n 
A 1 456 ARG 456 456 ?   ?   ?   A . n 
A 1 457 ALA 457 457 ?   ?   ?   A . n 
A 1 458 GLU 458 458 ?   ?   ?   A . n 
A 1 459 VAL 459 459 ?   ?   ?   A . n 
A 1 460 VAL 460 460 ?   ?   ?   A . n 
A 1 461 LYS 461 461 ?   ?   ?   A . n 
A 1 462 VAL 462 462 ?   ?   ?   A . n 
A 1 463 ASN 463 463 ?   ?   ?   A . n 
A 1 464 GLN 464 464 ?   ?   ?   A . n 
A 1 465 MET 465 465 ?   ?   ?   A . n 
A 1 466 SER 466 466 ?   ?   ?   A . n 
A 1 467 ALA 467 467 ?   ?   ?   A . n 
A 1 468 GLU 468 468 ?   ?   ?   A . n 
A 1 469 GLU 469 469 ?   ?   ?   A . n 
A 1 470 THR 470 470 ?   ?   ?   A . n 
A 1 471 LYS 471 471 ?   ?   ?   A . n 
A 1 472 HIS 472 472 ?   ?   ?   A . n 
A 1 473 LEU 473 473 ?   ?   ?   A . n 
A 1 474 ILE 474 474 ?   ?   ?   A . n 
A 1 475 LEU 475 475 ?   ?   ?   A . n 
A 1 476 ASP 476 476 ?   ?   ?   A . n 
A 1 477 ARG 477 477 ?   ?   ?   A . n 
A 1 478 GLY 478 478 ?   ?   ?   A . n 
A 1 479 VAL 479 479 ?   ?   ?   A . n 
A 1 480 SER 480 480 ?   ?   ?   A . n 
A 1 481 GLY 481 481 ?   ?   ?   A . n 
A 1 482 ASP 482 482 ?   ?   ?   A . n 
A 1 483 LEU 483 483 ?   ?   ?   A . n 
A 1 484 PRO 484 484 ?   ?   ?   A . n 
A 1 485 TRP 485 485 ?   ?   ?   A . n 
A 1 486 GLU 486 486 ?   ?   ?   A . n 
A 1 487 LYS 487 487 ?   ?   ?   A . n 
A 1 488 MET 488 488 ?   ?   ?   A . n 
A 1 489 THR 489 489 ?   ?   ?   A . n 
A 1 490 SER 490 490 ?   ?   ?   A . n 
A 1 491 ASN 491 491 ?   ?   ?   A . n 
A 1 492 THR 492 492 ?   ?   ?   A . n 
A 1 493 THR 493 493 ?   ?   ?   A . n 
A 1 494 PHE 494 494 ?   ?   ?   A . n 
A 1 495 ILE 495 495 ?   ?   ?   A . n 
A 1 496 SER 496 496 ?   ?   ?   A . n 
A 1 497 ASP 497 497 ?   ?   ?   A . n 
A 1 498 HIS 498 498 ?   ?   ?   A . n 
A 1 499 LEU 499 499 ?   ?   ?   A . n 
A 1 500 LEU 500 500 ?   ?   ?   A . n 
A 1 501 ALA 501 501 ?   ?   ?   A . n 
A 1 502 LYS 502 502 ?   ?   ?   A . n 
A 1 503 GLY 503 503 ?   ?   ?   A . n 
A 1 504 VAL 504 504 ?   ?   ?   A . n 
A 1 505 THR 505 505 ?   ?   ?   A . n 
A 1 506 ASP 506 506 ?   ?   ?   A . n 
A 1 507 GLN 507 507 ?   ?   ?   A . n 
A 1 508 VAL 508 508 ?   ?   ?   A . n 
A 1 509 PHE 509 509 ?   ?   ?   A . n 
A 1 510 PHE 510 510 ?   ?   ?   A . n 
A 1 511 GLU 511 511 ?   ?   ?   A . n 
A 1 512 LYS 512 512 ?   ?   ?   A . n 
A 1 513 LYS 513 513 ?   ?   ?   A . n 
A 1 514 SER 514 514 ?   ?   ?   A . n 
A 1 515 LYS 515 515 ?   ?   ?   A . n 
A 1 516 GLY 516 516 ?   ?   ?   A . n 
A 1 517 LYS 517 517 ?   ?   ?   A . n 
A 1 518 LYS 518 518 ?   ?   ?   A . n 
A 1 519 LYS 519 519 ?   ?   ?   A . n 
A 1 520 GLY 520 520 ?   ?   ?   A . n 
A 1 521 THR 521 521 ?   ?   ?   A . n 
A 1 522 GLU 522 522 ?   ?   ?   A . n 
A 1 523 THR 523 523 ?   ?   ?   A . n 
A 1 524 VAL 524 524 ?   ?   ?   A . n 
A 1 525 LYS 525 525 ?   ?   ?   A . n 
A 1 526 ARG 526 526 ?   ?   ?   A . n 
A 1 527 LYS 527 527 ?   ?   ?   A . n 
A 1 528 ASP 528 528 ?   ?   ?   A . n 
A 1 529 TYR 529 529 ?   ?   ?   A . n 
A 1 530 GLY 530 530 ?   ?   ?   A . n 
A 1 531 TRP 531 531 ?   ?   ?   A . n 
A 1 532 VAL 532 532 ?   ?   ?   A . n 
A 1 533 LYS 533 533 ?   ?   ?   A . n 
A 1 534 LEU 534 534 ?   ?   ?   A . n 
A 1 535 LEU 535 535 ?   ?   ?   A . n 
A 1 536 ARG 536 536 ?   ?   ?   A . n 
A 1 537 PRO 537 537 ?   ?   ?   A . n 
A 1 538 ARG 538 538 ?   ?   ?   A . n 
A 1 539 LEU 539 539 ?   ?   ?   A . n 
A 1 540 SER 540 540 ?   ?   ?   A . n 
A 1 541 GLN 541 541 ?   ?   ?   A . n 
A 1 542 GLU 542 542 ?   ?   ?   A . n 
A 1 543 THR 543 543 ?   ?   ?   A . n 
A 1 544 ARG 544 544 ?   ?   ?   A . n 
A 1 545 LYS 545 545 ?   ?   ?   A . n 
A 1 546 ALA 546 546 ?   ?   ?   A . n 
A 1 547 VAL 547 547 ?   ?   ?   A . n 
A 1 548 ASN 548 548 ?   ?   ?   A . n 
A 1 549 ASP 549 549 ?   ?   ?   A . n 
A 1 550 LYS 550 550 ?   ?   ?   A . n 
A 1 551 THR 551 551 ?   ?   ?   A . n 
A 1 552 TRP 552 552 ?   ?   ?   A . n 
A 1 553 GLU 553 553 ?   ?   ?   A . n 
A 1 554 LEU 554 554 ?   ?   ?   A . n 
A 1 555 LYS 555 555 ?   ?   ?   A . n 
A 1 556 ARG 556 556 ?   ?   ?   A . n 
A 1 557 ALA 557 557 ?   ?   ?   A . n 
A 1 558 SER 558 558 ?   ?   ?   A . n 
A 1 559 THR 559 559 ?   ?   ?   A . n 
A 1 560 GLU 560 560 ?   ?   ?   A . n 
A 1 561 TYR 561 561 ?   ?   ?   A . n 
A 1 562 VAL 562 562 ?   ?   ?   A . n 
A 1 563 ARG 563 563 ?   ?   ?   A . n 
A 1 564 LEU 564 564 ?   ?   ?   A . n 
A 1 565 SER 565 565 ?   ?   ?   A . n 
A 1 566 ARG 566 566 ?   ?   ?   A . n 
A 1 567 ARG 567 567 ?   ?   ?   A . n 
A 1 568 LYS 568 568 ?   ?   ?   A . n 
A 1 569 THR 569 569 ?   ?   ?   A . n 
A 1 570 GLU 570 570 ?   ?   ?   A . n 
A 1 571 LEU 571 571 ?   ?   ?   A . n 
A 1 572 ALA 572 572 ?   ?   ?   A . n 
A 1 573 ARG 573 573 ?   ?   ?   A . n 
A 1 574 ARG 574 574 ?   ?   ?   A . n 
A 1 575 CYS 575 575 ?   ?   ?   A . n 
A 1 576 VAL 576 576 ?   ?   ?   A . n 
A 1 577 ASN 577 577 ?   ?   ?   A . n 
A 1 578 TYR 578 578 ?   ?   ?   A . n 
A 1 579 ILE 579 579 ?   ?   ?   A . n 
A 1 580 VAL 580 580 ?   ?   ?   A . n 
A 1 581 ARG 581 581 ?   ?   ?   A . n 
A 1 582 GLU 582 582 ?   ?   ?   A . n 
A 1 583 THR 583 583 ?   ?   ?   A . n 
A 1 584 LYS 584 584 ?   ?   ?   A . n 
A 1 585 ARG 585 585 ?   ?   ?   A . n 
A 1 586 TRP 586 586 ?   ?   ?   A . n 
A 1 587 THR 587 587 ?   ?   ?   A . n 
A 1 588 GLN 588 588 ?   ?   ?   A . n 
A 1 589 CYS 589 589 ?   ?   ?   A . n 
A 1 590 GLU 590 590 ?   ?   ?   A . n 
A 1 591 ASP 591 591 ?   ?   ?   A . n 
A 1 592 ILE 592 592 ?   ?   ?   A . n 
A 1 593 ALA 593 593 ?   ?   ?   A . n 
A 1 594 ILE 594 594 ?   ?   ?   A . n 
A 1 595 VAL 595 595 ?   ?   ?   A . n 
A 1 596 ILE 596 596 ?   ?   ?   A . n 
A 1 597 GLU 597 597 ?   ?   ?   A . n 
A 1 598 ASP 598 598 ?   ?   ?   A . n 
A 1 599 LEU 599 599 ?   ?   ?   A . n 
A 1 600 ASN 600 600 ?   ?   ?   A . n 
A 1 601 VAL 601 601 ?   ?   ?   A . n 
A 1 602 ARG 602 602 ?   ?   ?   A . n 
A 1 603 PHE 603 603 ?   ?   ?   A . n 
A 1 604 PHE 604 604 ?   ?   ?   A . n 
A 1 605 HIS 605 605 ?   ?   ?   A . n 
A 1 606 GLY 606 606 ?   ?   ?   A . n 
A 1 607 SER 607 607 ?   ?   ?   A . n 
A 1 608 GLY 608 608 ?   ?   ?   A . n 
A 1 609 GLU 609 609 ?   ?   ?   A . n 
A 1 610 ARG 610 610 ?   ?   ?   A . n 
A 1 611 PRO 611 611 ?   ?   ?   A . n 
A 1 612 ASP 612 612 ?   ?   ?   A . n 
A 1 613 GLY 613 613 ?   ?   ?   A . n 
A 1 614 TRP 614 614 ?   ?   ?   A . n 
A 1 615 ASP 615 615 ?   ?   ?   A . n 
A 1 616 ASN 616 616 ?   ?   ?   A . n 
A 1 617 PHE 617 617 ?   ?   ?   A . n 
A 1 618 PHE 618 618 ?   ?   ?   A . n 
A 1 619 ILE 619 619 ?   ?   ?   A . n 
A 1 620 SER 620 620 ?   ?   ?   A . n 
A 1 621 LYS 621 621 ?   ?   ?   A . n 
A 1 622 ARG 622 622 ?   ?   ?   A . n 
A 1 623 GLU 623 623 ?   ?   ?   A . n 
A 1 624 ASN 624 624 ?   ?   ?   A . n 
A 1 625 ARG 625 625 ?   ?   ?   A . n 
A 1 626 TRP 626 626 ?   ?   ?   A . n 
A 1 627 PHE 627 627 ?   ?   ?   A . n 
A 1 628 ILE 628 628 ?   ?   ?   A . n 
A 1 629 GLN 629 629 ?   ?   ?   A . n 
A 1 630 VAL 630 630 ?   ?   ?   A . n 
A 1 631 LEU 631 631 ?   ?   ?   A . n 
A 1 632 HIS 632 632 ?   ?   ?   A . n 
A 1 633 LYS 633 633 ?   ?   ?   A . n 
A 1 634 ALA 634 634 ?   ?   ?   A . n 
A 1 635 PHE 635 635 ?   ?   ?   A . n 
A 1 636 SER 636 636 ?   ?   ?   A . n 
A 1 637 ASP 637 637 ?   ?   ?   A . n 
A 1 638 LEU 638 638 ?   ?   ?   A . n 
A 1 639 ALA 639 639 ?   ?   ?   A . n 
A 1 640 LEU 640 640 ?   ?   ?   A . n 
A 1 641 HIS 641 641 ?   ?   ?   A . n 
A 1 642 ARG 642 642 ?   ?   ?   A . n 
A 1 643 GLY 643 643 ?   ?   ?   A . n 
A 1 644 LEU 644 644 ?   ?   ?   A . n 
A 1 645 PRO 645 645 ?   ?   ?   A . n 
A 1 646 VAL 646 646 ?   ?   ?   A . n 
A 1 647 ILE 647 647 ?   ?   ?   A . n 
A 1 648 GLU 648 648 ?   ?   ?   A . n 
A 1 649 ALA 649 649 ?   ?   ?   A . n 
A 1 650 ASN 650 650 ?   ?   ?   A . n 
A 1 651 PRO 651 651 ?   ?   ?   A . n 
A 1 652 ALA 652 652 ?   ?   ?   A . n 
A 1 653 ARG 653 653 ?   ?   ?   A . n 
A 1 654 THR 654 654 ?   ?   ?   A . n 
A 1 655 SER 655 655 ?   ?   ?   A . n 
A 1 656 ILE 656 656 ?   ?   ?   A . n 
A 1 657 THR 657 657 ?   ?   ?   A . n 
A 1 658 CYS 658 658 ?   ?   ?   A . n 
A 1 659 ILE 659 659 ?   ?   ?   A . n 
A 1 660 ARG 660 660 ?   ?   ?   A . n 
A 1 661 CYS 661 661 ?   ?   ?   A . n 
A 1 662 GLY 662 662 ?   ?   ?   A . n 
A 1 663 HIS 663 663 ?   ?   ?   A . n 
A 1 664 CYS 664 664 ?   ?   ?   A . n 
A 1 665 ASP 665 665 ?   ?   ?   A . n 
A 1 666 ARG 666 666 ?   ?   ?   A . n 
A 1 667 ASN 667 667 ?   ?   ?   A . n 
A 1 668 ASN 668 668 ?   ?   ?   A . n 
A 1 669 ARG 669 669 ?   ?   ?   A . n 
A 1 670 HIS 670 670 ?   ?   ?   A . n 
A 1 671 GLY 671 671 ?   ?   ?   A . n 
A 1 672 GLU 672 672 ?   ?   ?   A . n 
A 1 673 MET 673 673 ?   ?   ?   A . n 
A 1 674 PHE 674 674 ?   ?   ?   A . n 
A 1 675 LEU 675 675 ?   ?   ?   A . n 
A 1 676 CYS 676 676 ?   ?   ?   A . n 
A 1 677 LEU 677 677 ?   ?   ?   A . n 
A 1 678 SER 678 678 ?   ?   ?   A . n 
A 1 679 CYS 679 679 ?   ?   ?   A . n 
A 1 680 ASN 680 680 ?   ?   ?   A . n 
A 1 681 ASP 681 681 ?   ?   ?   A . n 
A 1 682 LEU 682 682 ?   ?   ?   A . n 
A 1 683 ARG 683 683 ?   ?   ?   A . n 
A 1 684 HIS 684 684 ?   ?   ?   A . n 
A 1 685 ALA 685 685 ?   ?   ?   A . n 
A 1 686 ASP 686 686 ?   ?   ?   A . n 
A 1 687 ARG 687 687 ?   ?   ?   A . n 
A 1 688 GLU 688 688 ?   ?   ?   A . n 
A 1 689 ILE 689 689 ?   ?   ?   A . n 
A 1 690 ALA 690 690 ?   ?   ?   A . n 
A 1 691 THR 691 691 ?   ?   ?   A . n 
A 1 692 ARG 692 692 ?   ?   ?   A . n 
A 1 693 ASN 693 693 ?   ?   ?   A . n 
A 1 694 LEU 694 694 ?   ?   ?   A . n 
A 1 695 THR 695 695 ?   ?   ?   A . n 
A 1 696 ARG 696 696 ?   ?   ?   A . n 
A 1 697 VAL 697 697 ?   ?   ?   A . n 
A 1 698 ALA 698 698 ?   ?   ?   A . n 
A 1 699 VAL 699 699 ?   ?   ?   A . n 
A 1 700 THR 700 700 ?   ?   ?   A . n 
A 1 701 GLY 701 701 ?   ?   ?   A . n 
A 1 702 GLU 702 702 ?   ?   ?   A . n 
A 1 703 MET 703 703 ?   ?   ?   A . n 
A 1 704 ILE 704 704 ?   ?   ?   A . n 
A 1 705 PRO 705 705 ?   ?   ?   A . n 
A 1 706 ARG 706 706 ?   ?   ?   A . n 
A 1 707 ARG 707 707 ?   ?   ?   A . n 
A 1 708 ILE 708 708 ?   ?   ?   A . n 
A 1 709 GLU 709 709 ?   ?   ?   A . n 
A 1 710 PRO 710 710 ?   ?   ?   A . n 
A 1 711 GLY 711 711 ?   ?   ?   A . n 
A 1 712 GLU 712 712 ?   ?   ?   A . n 
A 1 713 GLN 713 713 ?   ?   ?   A . n 
A 1 714 SER 714 714 ?   ?   ?   A . n 
A 1 715 GLY 715 715 ?   ?   ?   A . n 
A 1 716 ASP 716 716 ?   ?   ?   A . n 
A 1 717 THR 717 717 ?   ?   ?   A . n 
A 1 718 LYS 718 718 ?   ?   ?   A . n 
A 1 719 LYS 719 719 ?   ?   ?   A . n 
A 1 720 ALA 720 720 ?   ?   ?   A . n 
A 1 721 ARG 721 721 ?   ?   ?   A . n 
A 1 722 SER 722 722 ?   ?   ?   A . n 
A 1 723 ALA 723 723 ?   ?   ?   A . n 
A 1 724 ARG 724 724 ?   ?   ?   A . n 
A 1 725 LYS 725 725 ?   ?   ?   A . n 
A 1 726 GLY 726 726 ?   ?   ?   A . n 
A 1 727 LYS 727 727 ?   ?   ?   A . n 
A 1 728 LYS 728 728 ?   ?   ?   A . n 
A 1 729 ALA 729 729 ?   ?   ?   A . n 
A 1 730 VAL 730 730 ?   ?   ?   A . n 
A 1 731 ILE 731 731 ?   ?   ?   A . n 
A 1 732 SER 732 732 ?   ?   ?   A . n 
A 1 733 LYS 733 733 ?   ?   ?   A . n 
A 1 734 ARG 734 734 ?   ?   ?   A . n 
A 1 735 GLU 735 735 ?   ?   ?   A . n 
A 1 736 ALA 736 736 ?   ?   ?   A . n 
A 1 737 ALA 737 737 ?   ?   ?   A . n 
B 2 1   U   1   -25 ?   ?   ?   B . n 
B 2 2   C   2   -24 ?   ?   ?   B . n 
B 2 3   A   3   -23 ?   ?   ?   B . n 
B 2 4   A   4   -22 ?   ?   ?   B . n 
B 2 5   C   5   -21 -21 C   C   B . n 
B 2 6   G   6   -20 -20 G   G   B . n 
B 2 7   C   7   -19 -19 C   C   B . n 
B 2 8   U   8   -18 -18 U   U   B . n 
B 2 9   U   9   -17 -17 U   U   B . n 
B 2 10  G   10  -16 -16 G   G   B . n 
B 2 11  C   11  -15 -15 C   C   B . n 
B 2 12  U   12  -14 -14 U   U   B . n 
B 2 13  C   13  -13 -13 C   C   B . n 
B 2 14  G   14  -12 -12 G   G   B . n 
B 2 15  G   15  -11 -11 G   G   B . n 
B 2 16  U   16  -10 -10 U   U   B . n 
B 2 17  U   17  -9  -9  U   U   B . n 
B 2 18  C   18  -8  -8  C   C   B . n 
B 2 19  G   19  -7  -7  G   G   B . n 
B 2 20  C   20  -6  -6  C   C   B . n 
B 2 21  C   21  -5  -5  C   C   B . n 
B 2 22  G   22  -4  -4  G   G   B . n 
B 2 23  A   23  -3  -3  A   A   B . n 
B 2 24  G   24  -2  -2  G   G   B . n 
B 2 25  A   25  -1  -1  A   A   B . n 
B 2 26  C   26  0   0   C   C   B . n 
B 2 27  U   27  1   1   U   U   B . n 
B 2 28  C   28  2   2   C   C   B . n 
B 2 29  C   29  3   3   C   C   B . n 
B 2 30  C   30  4   4   C   C   B . n 
B 2 31  C   31  5   ?   ?   ?   B . n 
B 2 32  U   32  6   ?   ?   ?   B . n 
B 2 33  A   33  7   ?   ?   ?   B . n 
B 2 34  C   34  8   ?   ?   ?   B . n 
B 2 35  G   35  9   ?   ?   ?   B . n 
B 2 36  U   36  10  ?   ?   ?   B . n 
B 2 37  G   37  11  ?   ?   ?   B . n 
B 2 38  C   38  12  ?   ?   ?   B . n 
B 2 39  U   39  13  ?   ?   ?   B . n 
B 2 40  G   40  14  ?   ?   ?   B . n 
B 2 41  C   41  15  ?   ?   ?   B . n 
B 2 42  U   42  16  ?   ?   ?   B . n 
B 2 43  G   43  17  ?   ?   ?   B . n 
B 2 44  A   44  18  ?   ?   ?   B . n 
B 2 45  A   45  19  ?   ?   ?   B . n 
B 2 46  G   46  20  ?   ?   ?   B . n 
C 3 1   DC  1   -32 ?   ?   ?   C . n 
C 3 2   DT  2   -31 ?   ?   ?   C . n 
C 3 3   DG  3   -30 ?   ?   ?   C . n 
C 3 4   DC  4   -29 ?   ?   ?   C . n 
C 3 5   DC  5   -28 ?   ?   ?   C . n 
C 3 6   DC  6   -27 ?   ?   ?   C . n 
C 3 7   DT  7   -26 ?   ?   ?   C . n 
C 3 8   DT  8   -25 ?   ?   ?   C . n 
C 3 9   DG  9   -24 ?   ?   ?   C . n 
C 3 10  DC  10  -23 ?   ?   ?   C . n 
C 3 11  DA  11  -22 ?   ?   ?   C . n 
C 3 12  DA  12  -21 ?   ?   ?   C . n 
C 3 13  DG  13  -20 ?   ?   ?   C . n 
C 3 14  DA  14  -19 ?   ?   ?   C . n 
C 3 15  DA  15  -18 ?   ?   ?   C . n 
C 3 16  DG  16  -17 ?   ?   ?   C . n 
C 3 17  DT  17  -16 ?   ?   ?   C . n 
C 3 18  DC  18  -15 ?   ?   ?   C . n 
C 3 19  DG  19  -14 ?   ?   ?   C . n 
C 3 20  DT  20  -13 ?   ?   ?   C . n 
C 3 21  DC  21  -12 ?   ?   ?   C . n 
C 3 22  DG  22  -11 ?   ?   ?   C . n 
C 3 23  DT  23  -10 ?   ?   ?   C . n 
C 3 24  DG  24  -9  ?   ?   ?   C . n 
C 3 25  DC  25  -8  ?   ?   ?   C . n 
C 3 26  DA  26  -7  ?   ?   ?   C . n 
C 3 27  DT  27  -6  ?   ?   ?   C . n 
C 3 28  DG  28  -5  ?   ?   ?   C . n 
C 3 29  DG  29  -4  -4  DG  DG  C . n 
C 3 30  DG  30  -3  -3  DG  DG  C . n 
C 3 31  DG  31  -2  -2  DG  DG  C . n 
C 3 32  DA  32  -1  -1  DA  DA  C . n 
C 3 33  DG  33  0   0   DG  DG  C . n 
C 3 34  DA  34  1   1   DA  DA  C . n 
C 3 35  DA  35  2   2   DA  DA  C . n 
C 3 36  DT  36  3   3   DT  DT  C . n 
C 3 37  DT  37  4   4   DT  DT  C . n 
C 3 38  DG  38  5   5   DG  DG  C . n 
C 3 39  DG  39  6   6   DG  DG  C . n 
C 3 40  DC  40  7   7   DC  DC  C . n 
C 3 41  DC  41  8   8   DC  DC  C . n 
C 3 42  DA  42  9   9   DA  DA  C . n 
D 4 1   DT  1   -9  -9  DT  DT  D . n 
D 4 2   DG  2   -8  -8  DG  DG  D . n 
D 4 3   DG  3   -7  -7  DG  DG  D . n 
D 4 4   DC  4   -6  -6  DC  DC  D . n 
D 4 5   DC  5   -5  -5  DC  DC  D . n 
D 4 6   DA  6   -4  -4  DA  DA  D . n 
D 4 7   DA  7   -3  -3  DA  DA  D . n 
D 4 8   DT  8   -2  -2  DT  DT  D . n 
D 4 9   DT  9   -1  -1  DT  DT  D . n 
D 4 10  DC  10  0   0   DC  DC  D . n 
D 4 11  DT  11  1   1   DT  DT  D . n 
D 4 12  DC  12  2   ?   ?   ?   D . n 
D 4 13  DC  13  3   ?   ?   ?   D . n 
D 4 14  DC  14  4   ?   ?   ?   D . n 
D 4 15  DC  15  5   ?   ?   ?   D . n 
D 4 16  DA  16  6   ?   ?   ?   D . n 
D 4 17  DT  17  7   ?   ?   ?   D . n 
D 4 18  DG  18  8   ?   ?   ?   D . n 
D 4 19  DC  19  9   ?   ?   ?   D . n 
D 4 20  DA  20  10  ?   ?   ?   D . n 
D 4 21  DC  21  11  ?   ?   ?   D . n 
D 4 22  DG  22  12  ?   ?   ?   D . n 
D 4 23  DA  23  13  ?   ?   ?   D . n 
D 4 24  DC  24  14  ?   ?   ?   D . n 
D 4 25  DG  25  15  ?   ?   ?   D . n 
D 4 26  DA  26  16  ?   ?   ?   D . n 
D 4 27  DC  27  17  ?   ?   ?   D . n 
D 4 28  DT  28  18  ?   ?   ?   D . n 
D 4 29  DT  29  19  ?   ?   ?   D . n 
D 4 30  DC  30  20  ?   ?   ?   D . n 
D 4 31  DT  31  21  ?   ?   ?   D . n 
D 4 32  DT  32  22  ?   ?   ?   D . n 
D 4 33  DG  33  23  ?   ?   ?   D . n 
D 4 34  DC  34  24  ?   ?   ?   D . n 
D 4 35  DA  35  25  ?   ?   ?   D . n 
D 4 36  DA  36  26  ?   ?   ?   D . n 
D 4 37  DG  37  27  ?   ?   ?   D . n 
D 4 38  DG  38  28  ?   ?   ?   D . n 
D 4 39  DG  39  29  ?   ?   ?   D . n 
D 4 40  DC  40  30  ?   ?   ?   D . n 
D 4 41  DA  41  31  ?   ?   ?   D . n 
D 4 42  DG  42  32  ?   ?   ?   D . n 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 Y 1 A PRO 324 ? CB ? A PRO 324 CB 
2 1 Y 1 A PRO 324 ? CG ? A PRO 324 CG 
3 1 Y 1 A PRO 324 ? CD ? A PRO 324 CD 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8WS9 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8WS9 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8WS9 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 8WS9 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.003  ? 3648 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.682  ? 5175 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 23.505 ? 891  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.039  ? 585  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.007  ? 487  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8WS9 
_struct.title                        'Cryo-EM mini structure of Cas12-1 with 5 nt complementary heteroduplex' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8WS9 
_struct_keywords.text            'Crispr-Cas12, RNA BINDING PROTEIN-RNA-DNA complex' 
_struct_keywords.pdbx_keywords   'RNA BINDING PROTEIN/RNA/DNA' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 8WS9 8WS9 ? 1 ? 1 
2 PDB 8WS9 8WS9 ? 2 ? 1 
3 PDB 8WS9 8WS9 ? 3 ? 1 
4 PDB 8WS9 8WS9 ? 4 ? 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8WS9 A 1 ? 737 ? 8WS9 1   ? 737 ? 1   737 
2 2 8WS9 B 1 ? 46  ? 8WS9 -25 ? 20  ? -25 20  
3 3 8WS9 C 1 ? 42  ? 8WS9 -32 ? 9   ? -32 9   
4 4 8WS9 D 1 ? 42  ? 8WS9 -9  ? 32  ? -9  32  
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 AA1 PRO A 71  ? GLU A 74  ? PRO A 71  GLU A 74  5 ? 4  
HELX_P HELX_P2 AA2 TRP A 75  ? VAL A 88  ? TRP A 75  VAL A 88  1 ? 14 
HELX_P HELX_P3 AA3 SER A 105 ? ALA A 114 ? SER A 105 ALA A 114 1 ? 10 
HELX_P HELX_P4 AA4 ILE A 132 ? ASP A 141 ? ILE A 132 ASP A 141 1 ? 10 
HELX_P HELX_P5 AA5 GLY A 142 ? ASN A 151 ? GLY A 142 ASN A 151 1 ? 10 
HELX_P HELX_P6 AA6 TYR A 201 ? SER A 205 ? TYR A 201 SER A 205 5 ? 5  
HELX_P HELX_P7 AA7 ALA A 266 ? TRP A 270 ? ALA A 266 TRP A 270 5 ? 5  
HELX_P HELX_P8 AA8 ALA A 309 ? GLY A 320 ? ALA A 309 GLY A 320 1 ? 12 
HELX_P HELX_P9 AA9 LEU A 331 ? PHE A 335 ? LEU A 331 PHE A 335 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
hydrog1  hydrog ? ? B G  10 N1 ? ? ? 1_555 B A  25 N1 ? ? B G  -16 B A  -1 1_555 ? ? ? ? ? ? TYPE_8_PAIR  ? ? ? 
hydrog2  hydrog ? ? B G  10 O6 ? ? ? 1_555 B A  25 N6 ? ? B G  -16 B A  -1 1_555 ? ? ? ? ? ? TYPE_8_PAIR  ? ? ? 
hydrog3  hydrog ? ? B C  11 N3 ? ? ? 1_555 B G  24 N1 ? ? B C  -15 B G  -2 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog4  hydrog ? ? B C  11 N4 ? ? ? 1_555 B G  24 O6 ? ? B C  -15 B G  -2 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog5  hydrog ? ? B C  11 O2 ? ? ? 1_555 B G  24 N2 ? ? B C  -15 B G  -2 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog6  hydrog ? ? B U  12 N3 ? ? ? 1_555 B A  23 N1 ? ? B U  -14 B A  -3 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog7  hydrog ? ? B U  12 O4 ? ? ? 1_555 B A  23 N6 ? ? B U  -14 B A  -3 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog8  hydrog ? ? B C  13 O2 ? ? ? 1_555 B G  22 N1 ? ? B C  -13 B G  -4 1_555 ? ? ? ? ? ? 'C-G PAIR'   ? ? ? 
hydrog9  hydrog ? ? B G  14 N1 ? ? ? 1_555 B C  21 N3 ? ? B G  -12 B C  -5 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog10 hydrog ? ? B G  14 N2 ? ? ? 1_555 B C  21 O2 ? ? B G  -12 B C  -5 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog11 hydrog ? ? B G  14 O6 ? ? ? 1_555 B C  21 N4 ? ? B G  -12 B C  -5 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog12 hydrog ? ? B G  15 N1 ? ? ? 1_555 B C  21 N3 ? ? B G  -11 B C  -5 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog13 hydrog ? ? B G  15 N2 ? ? ? 1_555 B C  21 O2 ? ? B G  -11 B C  -5 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog14 hydrog ? ? B G  15 O6 ? ? ? 1_555 B C  21 N4 ? ? B G  -11 B C  -5 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog15 hydrog ? ? B U  27 O2 ? ? ? 1_555 C DA 32 N6 ? ? B U  1   C DA -1 1_555 ? ? ? ? ? ? 'U-DA PAIR'  ? ? ? 
hydrog16 hydrog ? ? B C  29 O2 ? ? ? 1_555 C DG 31 N2 ? ? B C  3   C DG -2 1_555 ? ? ? ? ? ? 'C-DG PAIR'  ? ? ? 
hydrog17 hydrog ? ? C DG 33 N1 ? ? ? 1_555 D DT 9  O2 ? ? C DG 0   D DT -1 1_555 ? ? ? ? ? ? TYPE_28_PAIR ? ? ? 
hydrog18 hydrog ? ? C DG 33 O6 ? ? ? 1_555 D DT 9  N3 ? ? C DG 0   D DT -1 1_555 ? ? ? ? ? ? TYPE_28_PAIR ? ? ? 
hydrog19 hydrog ? ? C DA 34 N1 ? ? ? 1_555 D DT 9  N3 ? ? C DA 1   D DT -1 1_555 ? ? ? ? ? ? 'DA-DT PAIR' ? ? ? 
hydrog20 hydrog ? ? C DA 35 N1 ? ? ? 1_555 D DT 8  N3 ? ? C DA 2   D DT -2 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog21 hydrog ? ? C DA 35 N6 ? ? ? 1_555 D DT 8  O4 ? ? C DA 2   D DT -2 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog22 hydrog ? ? C DT 36 N3 ? ? ? 1_555 D DA 7  N1 ? ? C DT 3   D DA -3 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog23 hydrog ? ? C DT 36 O4 ? ? ? 1_555 D DA 7  N6 ? ? C DT 3   D DA -3 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog24 hydrog ? ? C DT 37 N3 ? ? ? 1_555 D DA 6  N1 ? ? C DT 4   D DA -4 1_555 ? ? ? ? ? ? 'DT-DA PAIR' ? ? ? 
hydrog25 hydrog ? ? C DG 38 N1 ? ? ? 1_555 D DC 5  N3 ? ? C DG 5   D DC -5 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog26 hydrog ? ? C DG 38 N2 ? ? ? 1_555 D DC 5  O2 ? ? C DG 5   D DC -5 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog27 hydrog ? ? C DG 38 O6 ? ? ? 1_555 D DC 5  N4 ? ? C DG 5   D DC -5 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog28 hydrog ? ? C DG 39 N1 ? ? ? 1_555 D DC 4  N3 ? ? C DG 6   D DC -6 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog29 hydrog ? ? C DG 39 N2 ? ? ? 1_555 D DC 4  O2 ? ? C DG 6   D DC -6 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog30 hydrog ? ? C DG 39 O6 ? ? ? 1_555 D DC 4  N4 ? ? C DG 6   D DC -6 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog31 hydrog ? ? C DC 41 N3 ? ? ? 1_555 D DG 2  N1 ? ? C DC 8   D DG -8 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog32 hydrog ? ? C DC 41 N4 ? ? ? 1_555 D DG 2  O6 ? ? C DC 8   D DG -8 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog33 hydrog ? ? C DC 41 O2 ? ? ? 1_555 D DG 2  N2 ? ? C DC 8   D DG -8 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog34 hydrog ? ? C DA 42 N1 ? ? ? 1_555 D DT 1  N3 ? ? C DA 9   D DT -9 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
hydrog35 hydrog ? ? C DA 42 N6 ? ? ? 1_555 D DT 1  O4 ? ? C DA 9   D DT -9 1_555 ? ? ? ? ? ? WATSON-CRICK ? ? ? 
# 
_struct_conn_type.id          hydrog 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
_struct_sheet.id               AA1 
_struct_sheet.type             ? 
_struct_sheet.number_strands   7 
_struct_sheet.details          ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA1 5 6 ? anti-parallel 
AA1 6 7 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE A 198 ? TYR A 199 ? ILE A 198 TYR A 199 
AA1 2 VAL A 340 ? ASP A 342 ? VAL A 340 ASP A 342 
AA1 3 ILE A 347 ? THR A 351 ? ILE A 347 THR A 351 
AA1 4 PRO A 60  ? GLN A 68  ? PRO A 60  GLN A 68  
AA1 5 TRP A 304 ? ASP A 308 ? TRP A 304 ASP A 308 
AA1 6 PRO A 295 ? THR A 299 ? PRO A 295 THR A 299 
AA1 7 VAL A 207 ? PRO A 208 ? VAL A 207 PRO A 208 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ILE A 198 ? N ILE A 198 O LEU A 341 ? O LEU A 341 
AA1 2 3 N VAL A 340 ? N VAL A 340 O THR A 349 ? O THR A 349 
AA1 3 4 O ALA A 348 ? O ALA A 348 N VAL A 63  ? N VAL A 63  
AA1 4 5 N ASN A 64  ? N ASN A 64  O ASP A 308 ? O ASP A 308 
AA1 5 6 O ILE A 305 ? O ILE A 305 N VAL A 298 ? N VAL A 298 
AA1 6 7 O ILE A 297 ? O ILE A 297 N VAL A 207 ? N VAL A 207 
# 
_pdbx_entry_details.entry_id                   8WS9 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 SER A 73  ? ? -90.62  56.90   
2  1 ASN A 99  ? ? 72.73   -55.59  
3  1 PHE A 113 ? ? -96.05  -72.32  
4  1 THR A 124 ? ? -140.36 12.12   
5  1 PRO A 196 ? ? -85.33  39.60   
6  1 TYR A 201 ? ? -129.80 -169.40 
7  1 LEU A 236 ? ? -90.17  48.16   
8  1 GLU A 292 ? ? -104.33 67.38   
9  1 LYS A 302 ? ? -140.60 -15.14  
10 1 ALA A 322 ? ? -67.48  -178.91 
11 1 PRO A 324 ? ? 89.52   -33.60  
12 1 PRO A 343 ? ? -76.52  44.78   
13 1 ARG A 345 ? ? 68.91   -4.30   
14 1 LYS A 353 ? ? -101.35 -169.74 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8WS9 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8WS9 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.78 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               71612 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'The ternary complex of Cas12-1 with 5 nt complementary heteroduplex' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3, 4' 
# 
_em_imaging.entry_id                        8WS9 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1200 
_em_imaging.nominal_defocus_max             5000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8WS9 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8WS9 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1   ? A MET 1   
2   1 Y 1 A THR 2   ? A THR 2   
3   1 Y 1 A PRO 3   ? A PRO 3   
4   1 Y 1 A LYS 4   ? A LYS 4   
5   1 Y 1 A THR 5   ? A THR 5   
6   1 Y 1 A GLU 6   ? A GLU 6   
7   1 Y 1 A THR 7   ? A THR 7   
8   1 Y 1 A PRO 8   ? A PRO 8   
9   1 Y 1 A VAL 9   ? A VAL 9   
10  1 Y 1 A GLY 10  ? A GLY 10  
11  1 Y 1 A ALA 11  ? A ALA 11  
12  1 Y 1 A LEU 12  ? A LEU 12  
13  1 Y 1 A ILE 13  ? A ILE 13  
14  1 Y 1 A LYS 14  ? A LYS 14  
15  1 Y 1 A LYS 15  ? A LYS 15  
16  1 Y 1 A PHE 16  ? A PHE 16  
17  1 Y 1 A PHE 17  ? A PHE 17  
18  1 Y 1 A PRO 18  ? A PRO 18  
19  1 Y 1 A GLY 19  ? A GLY 19  
20  1 Y 1 A LYS 20  ? A LYS 20  
21  1 Y 1 A ARG 21  ? A ARG 21  
22  1 Y 1 A PHE 22  ? A PHE 22  
23  1 Y 1 A GLN 23  ? A GLN 23  
24  1 Y 1 A LYS 24  ? A LYS 24  
25  1 Y 1 A ASN 25  ? A ASN 25  
26  1 Y 1 A TYR 26  ? A TYR 26  
27  1 Y 1 A LEU 27  ? A LEU 27  
28  1 Y 1 A LYS 28  ? A LYS 28  
29  1 Y 1 A ASP 29  ? A ASP 29  
30  1 Y 1 A ALA 30  ? A ALA 30  
31  1 Y 1 A GLY 31  ? A GLY 31  
32  1 Y 1 A LYS 32  ? A LYS 32  
33  1 Y 1 A LYS 33  ? A LYS 33  
34  1 Y 1 A LEU 34  ? A LEU 34  
35  1 Y 1 A LYS 35  ? A LYS 35  
36  1 Y 1 A ARG 36  ? A ARG 36  
37  1 Y 1 A GLU 37  ? A GLU 37  
38  1 Y 1 A GLY 38  ? A GLY 38  
39  1 Y 1 A GLU 39  ? A GLU 39  
40  1 Y 1 A ALA 40  ? A ALA 40  
41  1 Y 1 A ALA 41  ? A ALA 41  
42  1 Y 1 A ALA 42  ? A ALA 42  
43  1 Y 1 A VAL 43  ? A VAL 43  
44  1 Y 1 A GLU 44  ? A GLU 44  
45  1 Y 1 A TYR 45  ? A TYR 45  
46  1 Y 1 A LEU 46  ? A LEU 46  
47  1 Y 1 A SER 47  ? A SER 47  
48  1 Y 1 A GLY 48  ? A GLY 48  
49  1 Y 1 A LYS 49  ? A LYS 49  
50  1 Y 1 A GLN 50  ? A GLN 50  
51  1 Y 1 A GLU 51  ? A GLU 51  
52  1 Y 1 A ASP 52  ? A ASP 52  
53  1 Y 1 A HIS 53  ? A HIS 53  
54  1 Y 1 A PRO 54  ? A PRO 54  
55  1 Y 1 A ALA 55  ? A ALA 55  
56  1 Y 1 A ASN 56  ? A ASN 56  
57  1 Y 1 A TYR 89  ? A TYR 89  
58  1 Y 1 A GLY 90  ? A GLY 90  
59  1 Y 1 A LEU 91  ? A LEU 91  
60  1 Y 1 A THR 92  ? A THR 92  
61  1 Y 1 A ALA 93  ? A ALA 93  
62  1 Y 1 A ALA 94  ? A ALA 94  
63  1 Y 1 A GLU 95  ? A GLU 95  
64  1 Y 1 A ARG 96  ? A ARG 96  
65  1 Y 1 A GLU 97  ? A GLU 97  
66  1 Y 1 A GLU 152 ? A GLU 152 
67  1 Y 1 A LYS 153 ? A LYS 153 
68  1 Y 1 A ARG 154 ? A ARG 154 
69  1 Y 1 A ARG 155 ? A ARG 155 
70  1 Y 1 A SER 156 ? A SER 156 
71  1 Y 1 A LYS 157 ? A LYS 157 
72  1 Y 1 A ALA 158 ? A ALA 158 
73  1 Y 1 A THR 159 ? A THR 159 
74  1 Y 1 A ARG 160 ? A ARG 160 
75  1 Y 1 A ILE 161 ? A ILE 161 
76  1 Y 1 A ASN 162 ? A ASN 162 
77  1 Y 1 A VAL 163 ? A VAL 163 
78  1 Y 1 A SER 164 ? A SER 164 
79  1 Y 1 A ARG 165 ? A ARG 165 
80  1 Y 1 A GLU 166 ? A GLU 166 
81  1 Y 1 A ALA 167 ? A ALA 167 
82  1 Y 1 A ASP 168 ? A ASP 168 
83  1 Y 1 A GLY 169 ? A GLY 169 
84  1 Y 1 A LEU 170 ? A LEU 170 
85  1 Y 1 A PRO 171 ? A PRO 171 
86  1 Y 1 A PRO 172 ? A PRO 172 
87  1 Y 1 A ILE 173 ? A ILE 173 
88  1 Y 1 A GLU 174 ? A GLU 174 
89  1 Y 1 A ALA 175 ? A ALA 175 
90  1 Y 1 A GLU 176 ? A GLU 176 
91  1 Y 1 A PRO 177 ? A PRO 177 
92  1 Y 1 A GLU 178 ? A GLU 178 
93  1 Y 1 A GLU 179 ? A GLU 179 
94  1 Y 1 A THR 180 ? A THR 180 
95  1 Y 1 A ALA 181 ? A ALA 181 
96  1 Y 1 A PHE 182 ? A PHE 182 
97  1 Y 1 A GLY 183 ? A GLY 183 
98  1 Y 1 A PRO 184 ? A PRO 184 
99  1 Y 1 A ASP 185 ? A ASP 185 
100 1 Y 1 A GLY 186 ? A GLY 186 
101 1 Y 1 A LYS 187 ? A LYS 187 
102 1 Y 1 A LEU 188 ? A LEU 188 
103 1 Y 1 A LYS 189 ? A LYS 189 
104 1 Y 1 A GLU 190 ? A GLU 190 
105 1 Y 1 A ARG 191 ? A ARG 191 
106 1 Y 1 A ALA 212 ? A ALA 212 
107 1 Y 1 A LYS 213 ? A LYS 213 
108 1 Y 1 A HIS 214 ? A HIS 214 
109 1 Y 1 A PRO 215 ? A PRO 215 
110 1 Y 1 A ALA 216 ? A ALA 216 
111 1 Y 1 A LEU 217 ? A LEU 217 
112 1 Y 1 A PRO 218 ? A PRO 218 
113 1 Y 1 A PHE 219 ? A PHE 219 
114 1 Y 1 A SER 220 ? A SER 220 
115 1 Y 1 A GLY 221 ? A GLY 221 
116 1 Y 1 A VAL 222 ? A VAL 222 
117 1 Y 1 A ASP 223 ? A ASP 223 
118 1 Y 1 A PRO 224 ? A PRO 224 
119 1 Y 1 A GLY 225 ? A GLY 225 
120 1 Y 1 A ALA 226 ? A ALA 226 
121 1 Y 1 A PRO 227 ? A PRO 227 
122 1 Y 1 A ALA 356 ? A ALA 356 
123 1 Y 1 A VAL 357 ? A VAL 357 
124 1 Y 1 A ALA 358 ? A ALA 358 
125 1 Y 1 A VAL 359 ? A VAL 359 
126 1 Y 1 A HIS 360 ? A HIS 360 
127 1 Y 1 A SER 361 ? A SER 361 
128 1 Y 1 A ARG 362 ? A ARG 362 
129 1 Y 1 A LYS 363 ? A LYS 363 
130 1 Y 1 A PRO 364 ? A PRO 364 
131 1 Y 1 A THR 365 ? A THR 365 
132 1 Y 1 A ARG 366 ? A ARG 366 
133 1 Y 1 A GLY 367 ? A GLY 367 
134 1 Y 1 A LYS 368 ? A LYS 368 
135 1 Y 1 A LYS 369 ? A LYS 369 
136 1 Y 1 A SER 370 ? A SER 370 
137 1 Y 1 A LYS 371 ? A LYS 371 
138 1 Y 1 A GLU 372 ? A GLU 372 
139 1 Y 1 A LEU 373 ? A LEU 373 
140 1 Y 1 A LEU 374 ? A LEU 374 
141 1 Y 1 A LEU 375 ? A LEU 375 
142 1 Y 1 A SER 376 ? A SER 376 
143 1 Y 1 A MET 377 ? A MET 377 
144 1 Y 1 A THR 378 ? A THR 378 
145 1 Y 1 A ALA 379 ? A ALA 379 
146 1 Y 1 A GLU 380 ? A GLU 380 
147 1 Y 1 A LYS 381 ? A LYS 381 
148 1 Y 1 A PRO 382 ? A PRO 382 
149 1 Y 1 A HIS 383 ? A HIS 383 
150 1 Y 1 A VAL 384 ? A VAL 384 
151 1 Y 1 A GLY 385 ? A GLY 385 
152 1 Y 1 A LEU 386 ? A LEU 386 
153 1 Y 1 A VAL 387 ? A VAL 387 
154 1 Y 1 A ALA 388 ? A ALA 388 
155 1 Y 1 A ILE 389 ? A ILE 389 
156 1 Y 1 A ASP 390 ? A ASP 390 
157 1 Y 1 A LEU 391 ? A LEU 391 
158 1 Y 1 A GLY 392 ? A GLY 392 
159 1 Y 1 A GLN 393 ? A GLN 393 
160 1 Y 1 A THR 394 ? A THR 394 
161 1 Y 1 A ASN 395 ? A ASN 395 
162 1 Y 1 A PRO 396 ? A PRO 396 
163 1 Y 1 A VAL 397 ? A VAL 397 
164 1 Y 1 A ALA 398 ? A ALA 398 
165 1 Y 1 A ALA 399 ? A ALA 399 
166 1 Y 1 A GLU 400 ? A GLU 400 
167 1 Y 1 A PHE 401 ? A PHE 401 
168 1 Y 1 A SER 402 ? A SER 402 
169 1 Y 1 A ARG 403 ? A ARG 403 
170 1 Y 1 A VAL 404 ? A VAL 404 
171 1 Y 1 A LYS 405 ? A LYS 405 
172 1 Y 1 A ARG 406 ? A ARG 406 
173 1 Y 1 A GLU 407 ? A GLU 407 
174 1 Y 1 A GLY 408 ? A GLY 408 
175 1 Y 1 A GLU 409 ? A GLU 409 
176 1 Y 1 A THR 410 ? A THR 410 
177 1 Y 1 A LEU 411 ? A LEU 411 
178 1 Y 1 A GLN 412 ? A GLN 412 
179 1 Y 1 A ALA 413 ? A ALA 413 
180 1 Y 1 A GLU 414 ? A GLU 414 
181 1 Y 1 A PRO 415 ? A PRO 415 
182 1 Y 1 A LEU 416 ? A LEU 416 
183 1 Y 1 A GLY 417 ? A GLY 417 
184 1 Y 1 A GLN 418 ? A GLN 418 
185 1 Y 1 A ILE 419 ? A ILE 419 
186 1 Y 1 A VAL 420 ? A VAL 420 
187 1 Y 1 A LEU 421 ? A LEU 421 
188 1 Y 1 A PRO 422 ? A PRO 422 
189 1 Y 1 A ASP 423 ? A ASP 423 
190 1 Y 1 A ASP 424 ? A ASP 424 
191 1 Y 1 A LEU 425 ? A LEU 425 
192 1 Y 1 A VAL 426 ? A VAL 426 
193 1 Y 1 A LYS 427 ? A LYS 427 
194 1 Y 1 A ASP 428 ? A ASP 428 
195 1 Y 1 A LEU 429 ? A LEU 429 
196 1 Y 1 A THR 430 ? A THR 430 
197 1 Y 1 A ARG 431 ? A ARG 431 
198 1 Y 1 A TYR 432 ? A TYR 432 
199 1 Y 1 A ARG 433 ? A ARG 433 
200 1 Y 1 A ARG 434 ? A ARG 434 
201 1 Y 1 A ALA 435 ? A ALA 435 
202 1 Y 1 A TRP 436 ? A TRP 436 
203 1 Y 1 A ASP 437 ? A ASP 437 
204 1 Y 1 A ALA 438 ? A ALA 438 
205 1 Y 1 A THR 439 ? A THR 439 
206 1 Y 1 A GLU 440 ? A GLU 440 
207 1 Y 1 A GLU 441 ? A GLU 441 
208 1 Y 1 A GLN 442 ? A GLN 442 
209 1 Y 1 A ILE 443 ? A ILE 443 
210 1 Y 1 A LYS 444 ? A LYS 444 
211 1 Y 1 A ALA 445 ? A ALA 445 
212 1 Y 1 A GLU 446 ? A GLU 446 
213 1 Y 1 A ALA 447 ? A ALA 447 
214 1 Y 1 A ILE 448 ? A ILE 448 
215 1 Y 1 A VAL 449 ? A VAL 449 
216 1 Y 1 A GLN 450 ? A GLN 450 
217 1 Y 1 A LEU 451 ? A LEU 451 
218 1 Y 1 A PRO 452 ? A PRO 452 
219 1 Y 1 A GLU 453 ? A GLU 453 
220 1 Y 1 A GLU 454 ? A GLU 454 
221 1 Y 1 A CYS 455 ? A CYS 455 
222 1 Y 1 A ARG 456 ? A ARG 456 
223 1 Y 1 A ALA 457 ? A ALA 457 
224 1 Y 1 A GLU 458 ? A GLU 458 
225 1 Y 1 A VAL 459 ? A VAL 459 
226 1 Y 1 A VAL 460 ? A VAL 460 
227 1 Y 1 A LYS 461 ? A LYS 461 
228 1 Y 1 A VAL 462 ? A VAL 462 
229 1 Y 1 A ASN 463 ? A ASN 463 
230 1 Y 1 A GLN 464 ? A GLN 464 
231 1 Y 1 A MET 465 ? A MET 465 
232 1 Y 1 A SER 466 ? A SER 466 
233 1 Y 1 A ALA 467 ? A ALA 467 
234 1 Y 1 A GLU 468 ? A GLU 468 
235 1 Y 1 A GLU 469 ? A GLU 469 
236 1 Y 1 A THR 470 ? A THR 470 
237 1 Y 1 A LYS 471 ? A LYS 471 
238 1 Y 1 A HIS 472 ? A HIS 472 
239 1 Y 1 A LEU 473 ? A LEU 473 
240 1 Y 1 A ILE 474 ? A ILE 474 
241 1 Y 1 A LEU 475 ? A LEU 475 
242 1 Y 1 A ASP 476 ? A ASP 476 
243 1 Y 1 A ARG 477 ? A ARG 477 
244 1 Y 1 A GLY 478 ? A GLY 478 
245 1 Y 1 A VAL 479 ? A VAL 479 
246 1 Y 1 A SER 480 ? A SER 480 
247 1 Y 1 A GLY 481 ? A GLY 481 
248 1 Y 1 A ASP 482 ? A ASP 482 
249 1 Y 1 A LEU 483 ? A LEU 483 
250 1 Y 1 A PRO 484 ? A PRO 484 
251 1 Y 1 A TRP 485 ? A TRP 485 
252 1 Y 1 A GLU 486 ? A GLU 486 
253 1 Y 1 A LYS 487 ? A LYS 487 
254 1 Y 1 A MET 488 ? A MET 488 
255 1 Y 1 A THR 489 ? A THR 489 
256 1 Y 1 A SER 490 ? A SER 490 
257 1 Y 1 A ASN 491 ? A ASN 491 
258 1 Y 1 A THR 492 ? A THR 492 
259 1 Y 1 A THR 493 ? A THR 493 
260 1 Y 1 A PHE 494 ? A PHE 494 
261 1 Y 1 A ILE 495 ? A ILE 495 
262 1 Y 1 A SER 496 ? A SER 496 
263 1 Y 1 A ASP 497 ? A ASP 497 
264 1 Y 1 A HIS 498 ? A HIS 498 
265 1 Y 1 A LEU 499 ? A LEU 499 
266 1 Y 1 A LEU 500 ? A LEU 500 
267 1 Y 1 A ALA 501 ? A ALA 501 
268 1 Y 1 A LYS 502 ? A LYS 502 
269 1 Y 1 A GLY 503 ? A GLY 503 
270 1 Y 1 A VAL 504 ? A VAL 504 
271 1 Y 1 A THR 505 ? A THR 505 
272 1 Y 1 A ASP 506 ? A ASP 506 
273 1 Y 1 A GLN 507 ? A GLN 507 
274 1 Y 1 A VAL 508 ? A VAL 508 
275 1 Y 1 A PHE 509 ? A PHE 509 
276 1 Y 1 A PHE 510 ? A PHE 510 
277 1 Y 1 A GLU 511 ? A GLU 511 
278 1 Y 1 A LYS 512 ? A LYS 512 
279 1 Y 1 A LYS 513 ? A LYS 513 
280 1 Y 1 A SER 514 ? A SER 514 
281 1 Y 1 A LYS 515 ? A LYS 515 
282 1 Y 1 A GLY 516 ? A GLY 516 
283 1 Y 1 A LYS 517 ? A LYS 517 
284 1 Y 1 A LYS 518 ? A LYS 518 
285 1 Y 1 A LYS 519 ? A LYS 519 
286 1 Y 1 A GLY 520 ? A GLY 520 
287 1 Y 1 A THR 521 ? A THR 521 
288 1 Y 1 A GLU 522 ? A GLU 522 
289 1 Y 1 A THR 523 ? A THR 523 
290 1 Y 1 A VAL 524 ? A VAL 524 
291 1 Y 1 A LYS 525 ? A LYS 525 
292 1 Y 1 A ARG 526 ? A ARG 526 
293 1 Y 1 A LYS 527 ? A LYS 527 
294 1 Y 1 A ASP 528 ? A ASP 528 
295 1 Y 1 A TYR 529 ? A TYR 529 
296 1 Y 1 A GLY 530 ? A GLY 530 
297 1 Y 1 A TRP 531 ? A TRP 531 
298 1 Y 1 A VAL 532 ? A VAL 532 
299 1 Y 1 A LYS 533 ? A LYS 533 
300 1 Y 1 A LEU 534 ? A LEU 534 
301 1 Y 1 A LEU 535 ? A LEU 535 
302 1 Y 1 A ARG 536 ? A ARG 536 
303 1 Y 1 A PRO 537 ? A PRO 537 
304 1 Y 1 A ARG 538 ? A ARG 538 
305 1 Y 1 A LEU 539 ? A LEU 539 
306 1 Y 1 A SER 540 ? A SER 540 
307 1 Y 1 A GLN 541 ? A GLN 541 
308 1 Y 1 A GLU 542 ? A GLU 542 
309 1 Y 1 A THR 543 ? A THR 543 
310 1 Y 1 A ARG 544 ? A ARG 544 
311 1 Y 1 A LYS 545 ? A LYS 545 
312 1 Y 1 A ALA 546 ? A ALA 546 
313 1 Y 1 A VAL 547 ? A VAL 547 
314 1 Y 1 A ASN 548 ? A ASN 548 
315 1 Y 1 A ASP 549 ? A ASP 549 
316 1 Y 1 A LYS 550 ? A LYS 550 
317 1 Y 1 A THR 551 ? A THR 551 
318 1 Y 1 A TRP 552 ? A TRP 552 
319 1 Y 1 A GLU 553 ? A GLU 553 
320 1 Y 1 A LEU 554 ? A LEU 554 
321 1 Y 1 A LYS 555 ? A LYS 555 
322 1 Y 1 A ARG 556 ? A ARG 556 
323 1 Y 1 A ALA 557 ? A ALA 557 
324 1 Y 1 A SER 558 ? A SER 558 
325 1 Y 1 A THR 559 ? A THR 559 
326 1 Y 1 A GLU 560 ? A GLU 560 
327 1 Y 1 A TYR 561 ? A TYR 561 
328 1 Y 1 A VAL 562 ? A VAL 562 
329 1 Y 1 A ARG 563 ? A ARG 563 
330 1 Y 1 A LEU 564 ? A LEU 564 
331 1 Y 1 A SER 565 ? A SER 565 
332 1 Y 1 A ARG 566 ? A ARG 566 
333 1 Y 1 A ARG 567 ? A ARG 567 
334 1 Y 1 A LYS 568 ? A LYS 568 
335 1 Y 1 A THR 569 ? A THR 569 
336 1 Y 1 A GLU 570 ? A GLU 570 
337 1 Y 1 A LEU 571 ? A LEU 571 
338 1 Y 1 A ALA 572 ? A ALA 572 
339 1 Y 1 A ARG 573 ? A ARG 573 
340 1 Y 1 A ARG 574 ? A ARG 574 
341 1 Y 1 A CYS 575 ? A CYS 575 
342 1 Y 1 A VAL 576 ? A VAL 576 
343 1 Y 1 A ASN 577 ? A ASN 577 
344 1 Y 1 A TYR 578 ? A TYR 578 
345 1 Y 1 A ILE 579 ? A ILE 579 
346 1 Y 1 A VAL 580 ? A VAL 580 
347 1 Y 1 A ARG 581 ? A ARG 581 
348 1 Y 1 A GLU 582 ? A GLU 582 
349 1 Y 1 A THR 583 ? A THR 583 
350 1 Y 1 A LYS 584 ? A LYS 584 
351 1 Y 1 A ARG 585 ? A ARG 585 
352 1 Y 1 A TRP 586 ? A TRP 586 
353 1 Y 1 A THR 587 ? A THR 587 
354 1 Y 1 A GLN 588 ? A GLN 588 
355 1 Y 1 A CYS 589 ? A CYS 589 
356 1 Y 1 A GLU 590 ? A GLU 590 
357 1 Y 1 A ASP 591 ? A ASP 591 
358 1 Y 1 A ILE 592 ? A ILE 592 
359 1 Y 1 A ALA 593 ? A ALA 593 
360 1 Y 1 A ILE 594 ? A ILE 594 
361 1 Y 1 A VAL 595 ? A VAL 595 
362 1 Y 1 A ILE 596 ? A ILE 596 
363 1 Y 1 A GLU 597 ? A GLU 597 
364 1 Y 1 A ASP 598 ? A ASP 598 
365 1 Y 1 A LEU 599 ? A LEU 599 
366 1 Y 1 A ASN 600 ? A ASN 600 
367 1 Y 1 A VAL 601 ? A VAL 601 
368 1 Y 1 A ARG 602 ? A ARG 602 
369 1 Y 1 A PHE 603 ? A PHE 603 
370 1 Y 1 A PHE 604 ? A PHE 604 
371 1 Y 1 A HIS 605 ? A HIS 605 
372 1 Y 1 A GLY 606 ? A GLY 606 
373 1 Y 1 A SER 607 ? A SER 607 
374 1 Y 1 A GLY 608 ? A GLY 608 
375 1 Y 1 A GLU 609 ? A GLU 609 
376 1 Y 1 A ARG 610 ? A ARG 610 
377 1 Y 1 A PRO 611 ? A PRO 611 
378 1 Y 1 A ASP 612 ? A ASP 612 
379 1 Y 1 A GLY 613 ? A GLY 613 
380 1 Y 1 A TRP 614 ? A TRP 614 
381 1 Y 1 A ASP 615 ? A ASP 615 
382 1 Y 1 A ASN 616 ? A ASN 616 
383 1 Y 1 A PHE 617 ? A PHE 617 
384 1 Y 1 A PHE 618 ? A PHE 618 
385 1 Y 1 A ILE 619 ? A ILE 619 
386 1 Y 1 A SER 620 ? A SER 620 
387 1 Y 1 A LYS 621 ? A LYS 621 
388 1 Y 1 A ARG 622 ? A ARG 622 
389 1 Y 1 A GLU 623 ? A GLU 623 
390 1 Y 1 A ASN 624 ? A ASN 624 
391 1 Y 1 A ARG 625 ? A ARG 625 
392 1 Y 1 A TRP 626 ? A TRP 626 
393 1 Y 1 A PHE 627 ? A PHE 627 
394 1 Y 1 A ILE 628 ? A ILE 628 
395 1 Y 1 A GLN 629 ? A GLN 629 
396 1 Y 1 A VAL 630 ? A VAL 630 
397 1 Y 1 A LEU 631 ? A LEU 631 
398 1 Y 1 A HIS 632 ? A HIS 632 
399 1 Y 1 A LYS 633 ? A LYS 633 
400 1 Y 1 A ALA 634 ? A ALA 634 
401 1 Y 1 A PHE 635 ? A PHE 635 
402 1 Y 1 A SER 636 ? A SER 636 
403 1 Y 1 A ASP 637 ? A ASP 637 
404 1 Y 1 A LEU 638 ? A LEU 638 
405 1 Y 1 A ALA 639 ? A ALA 639 
406 1 Y 1 A LEU 640 ? A LEU 640 
407 1 Y 1 A HIS 641 ? A HIS 641 
408 1 Y 1 A ARG 642 ? A ARG 642 
409 1 Y 1 A GLY 643 ? A GLY 643 
410 1 Y 1 A LEU 644 ? A LEU 644 
411 1 Y 1 A PRO 645 ? A PRO 645 
412 1 Y 1 A VAL 646 ? A VAL 646 
413 1 Y 1 A ILE 647 ? A ILE 647 
414 1 Y 1 A GLU 648 ? A GLU 648 
415 1 Y 1 A ALA 649 ? A ALA 649 
416 1 Y 1 A ASN 650 ? A ASN 650 
417 1 Y 1 A PRO 651 ? A PRO 651 
418 1 Y 1 A ALA 652 ? A ALA 652 
419 1 Y 1 A ARG 653 ? A ARG 653 
420 1 Y 1 A THR 654 ? A THR 654 
421 1 Y 1 A SER 655 ? A SER 655 
422 1 Y 1 A ILE 656 ? A ILE 656 
423 1 Y 1 A THR 657 ? A THR 657 
424 1 Y 1 A CYS 658 ? A CYS 658 
425 1 Y 1 A ILE 659 ? A ILE 659 
426 1 Y 1 A ARG 660 ? A ARG 660 
427 1 Y 1 A CYS 661 ? A CYS 661 
428 1 Y 1 A GLY 662 ? A GLY 662 
429 1 Y 1 A HIS 663 ? A HIS 663 
430 1 Y 1 A CYS 664 ? A CYS 664 
431 1 Y 1 A ASP 665 ? A ASP 665 
432 1 Y 1 A ARG 666 ? A ARG 666 
433 1 Y 1 A ASN 667 ? A ASN 667 
434 1 Y 1 A ASN 668 ? A ASN 668 
435 1 Y 1 A ARG 669 ? A ARG 669 
436 1 Y 1 A HIS 670 ? A HIS 670 
437 1 Y 1 A GLY 671 ? A GLY 671 
438 1 Y 1 A GLU 672 ? A GLU 672 
439 1 Y 1 A MET 673 ? A MET 673 
440 1 Y 1 A PHE 674 ? A PHE 674 
441 1 Y 1 A LEU 675 ? A LEU 675 
442 1 Y 1 A CYS 676 ? A CYS 676 
443 1 Y 1 A LEU 677 ? A LEU 677 
444 1 Y 1 A SER 678 ? A SER 678 
445 1 Y 1 A CYS 679 ? A CYS 679 
446 1 Y 1 A ASN 680 ? A ASN 680 
447 1 Y 1 A ASP 681 ? A ASP 681 
448 1 Y 1 A LEU 682 ? A LEU 682 
449 1 Y 1 A ARG 683 ? A ARG 683 
450 1 Y 1 A HIS 684 ? A HIS 684 
451 1 Y 1 A ALA 685 ? A ALA 685 
452 1 Y 1 A ASP 686 ? A ASP 686 
453 1 Y 1 A ARG 687 ? A ARG 687 
454 1 Y 1 A GLU 688 ? A GLU 688 
455 1 Y 1 A ILE 689 ? A ILE 689 
456 1 Y 1 A ALA 690 ? A ALA 690 
457 1 Y 1 A THR 691 ? A THR 691 
458 1 Y 1 A ARG 692 ? A ARG 692 
459 1 Y 1 A ASN 693 ? A ASN 693 
460 1 Y 1 A LEU 694 ? A LEU 694 
461 1 Y 1 A THR 695 ? A THR 695 
462 1 Y 1 A ARG 696 ? A ARG 696 
463 1 Y 1 A VAL 697 ? A VAL 697 
464 1 Y 1 A ALA 698 ? A ALA 698 
465 1 Y 1 A VAL 699 ? A VAL 699 
466 1 Y 1 A THR 700 ? A THR 700 
467 1 Y 1 A GLY 701 ? A GLY 701 
468 1 Y 1 A GLU 702 ? A GLU 702 
469 1 Y 1 A MET 703 ? A MET 703 
470 1 Y 1 A ILE 704 ? A ILE 704 
471 1 Y 1 A PRO 705 ? A PRO 705 
472 1 Y 1 A ARG 706 ? A ARG 706 
473 1 Y 1 A ARG 707 ? A ARG 707 
474 1 Y 1 A ILE 708 ? A ILE 708 
475 1 Y 1 A GLU 709 ? A GLU 709 
476 1 Y 1 A PRO 710 ? A PRO 710 
477 1 Y 1 A GLY 711 ? A GLY 711 
478 1 Y 1 A GLU 712 ? A GLU 712 
479 1 Y 1 A GLN 713 ? A GLN 713 
480 1 Y 1 A SER 714 ? A SER 714 
481 1 Y 1 A GLY 715 ? A GLY 715 
482 1 Y 1 A ASP 716 ? A ASP 716 
483 1 Y 1 A THR 717 ? A THR 717 
484 1 Y 1 A LYS 718 ? A LYS 718 
485 1 Y 1 A LYS 719 ? A LYS 719 
486 1 Y 1 A ALA 720 ? A ALA 720 
487 1 Y 1 A ARG 721 ? A ARG 721 
488 1 Y 1 A SER 722 ? A SER 722 
489 1 Y 1 A ALA 723 ? A ALA 723 
490 1 Y 1 A ARG 724 ? A ARG 724 
491 1 Y 1 A LYS 725 ? A LYS 725 
492 1 Y 1 A GLY 726 ? A GLY 726 
493 1 Y 1 A LYS 727 ? A LYS 727 
494 1 Y 1 A LYS 728 ? A LYS 728 
495 1 Y 1 A ALA 729 ? A ALA 729 
496 1 Y 1 A VAL 730 ? A VAL 730 
497 1 Y 1 A ILE 731 ? A ILE 731 
498 1 Y 1 A SER 732 ? A SER 732 
499 1 Y 1 A LYS 733 ? A LYS 733 
500 1 Y 1 A ARG 734 ? A ARG 734 
501 1 Y 1 A GLU 735 ? A GLU 735 
502 1 Y 1 A ALA 736 ? A ALA 736 
503 1 Y 1 A ALA 737 ? A ALA 737 
504 1 Y 1 B U   -25 ? B U   1   
505 1 Y 1 B C   -24 ? B C   2   
506 1 Y 1 B A   -23 ? B A   3   
507 1 Y 1 B A   -22 ? B A   4   
508 1 Y 1 B C   5   ? B C   31  
509 1 Y 1 B U   6   ? B U   32  
510 1 Y 1 B A   7   ? B A   33  
511 1 Y 1 B C   8   ? B C   34  
512 1 Y 1 B G   9   ? B G   35  
513 1 Y 1 B U   10  ? B U   36  
514 1 Y 1 B G   11  ? B G   37  
515 1 Y 1 B C   12  ? B C   38  
516 1 Y 1 B U   13  ? B U   39  
517 1 Y 1 B G   14  ? B G   40  
518 1 Y 1 B C   15  ? B C   41  
519 1 Y 1 B U   16  ? B U   42  
520 1 Y 1 B G   17  ? B G   43  
521 1 Y 1 B A   18  ? B A   44  
522 1 Y 1 B A   19  ? B A   45  
523 1 Y 1 B G   20  ? B G   46  
524 1 Y 1 C DC  -32 ? C DC  1   
525 1 Y 1 C DT  -31 ? C DT  2   
526 1 Y 1 C DG  -30 ? C DG  3   
527 1 Y 1 C DC  -29 ? C DC  4   
528 1 Y 1 C DC  -28 ? C DC  5   
529 1 Y 1 C DC  -27 ? C DC  6   
530 1 Y 1 C DT  -26 ? C DT  7   
531 1 Y 1 C DT  -25 ? C DT  8   
532 1 Y 1 C DG  -24 ? C DG  9   
533 1 Y 1 C DC  -23 ? C DC  10  
534 1 Y 1 C DA  -22 ? C DA  11  
535 1 Y 1 C DA  -21 ? C DA  12  
536 1 Y 1 C DG  -20 ? C DG  13  
537 1 Y 1 C DA  -19 ? C DA  14  
538 1 Y 1 C DA  -18 ? C DA  15  
539 1 Y 1 C DG  -17 ? C DG  16  
540 1 Y 1 C DT  -16 ? C DT  17  
541 1 Y 1 C DC  -15 ? C DC  18  
542 1 Y 1 C DG  -14 ? C DG  19  
543 1 Y 1 C DT  -13 ? C DT  20  
544 1 Y 1 C DC  -12 ? C DC  21  
545 1 Y 1 C DG  -11 ? C DG  22  
546 1 Y 1 C DT  -10 ? C DT  23  
547 1 Y 1 C DG  -9  ? C DG  24  
548 1 Y 1 C DC  -8  ? C DC  25  
549 1 Y 1 C DA  -7  ? C DA  26  
550 1 Y 1 C DT  -6  ? C DT  27  
551 1 Y 1 C DG  -5  ? C DG  28  
552 1 Y 1 D DC  2   ? D DC  12  
553 1 Y 1 D DC  3   ? D DC  13  
554 1 Y 1 D DC  4   ? D DC  14  
555 1 Y 1 D DC  5   ? D DC  15  
556 1 Y 1 D DA  6   ? D DA  16  
557 1 Y 1 D DT  7   ? D DT  17  
558 1 Y 1 D DG  8   ? D DG  18  
559 1 Y 1 D DC  9   ? D DC  19  
560 1 Y 1 D DA  10  ? D DA  20  
561 1 Y 1 D DC  11  ? D DC  21  
562 1 Y 1 D DG  12  ? D DG  22  
563 1 Y 1 D DA  13  ? D DA  23  
564 1 Y 1 D DC  14  ? D DC  24  
565 1 Y 1 D DG  15  ? D DG  25  
566 1 Y 1 D DA  16  ? D DA  26  
567 1 Y 1 D DC  17  ? D DC  27  
568 1 Y 1 D DT  18  ? D DT  28  
569 1 Y 1 D DT  19  ? D DT  29  
570 1 Y 1 D DC  20  ? D DC  30  
571 1 Y 1 D DT  21  ? D DT  31  
572 1 Y 1 D DT  22  ? D DT  32  
573 1 Y 1 D DG  23  ? D DG  33  
574 1 Y 1 D DC  24  ? D DC  34  
575 1 Y 1 D DA  25  ? D DA  35  
576 1 Y 1 D DA  26  ? D DA  36  
577 1 Y 1 D DG  27  ? D DG  37  
578 1 Y 1 D DG  28  ? D DG  38  
579 1 Y 1 D DG  29  ? D DG  39  
580 1 Y 1 D DC  30  ? D DC  40  
581 1 Y 1 D DA  31  ? D DA  41  
582 1 Y 1 D DG  32  ? D DG  42  
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A   OP3    O N N 1   
A   P      P N N 2   
A   OP1    O N N 3   
A   OP2    O N N 4   
A   "O5'"  O N N 5   
A   "C5'"  C N N 6   
A   "C4'"  C N R 7   
A   "O4'"  O N N 8   
A   "C3'"  C N S 9   
A   "O3'"  O N N 10  
A   "C2'"  C N R 11  
A   "O2'"  O N N 12  
A   "C1'"  C N R 13  
A   N9     N Y N 14  
A   C8     C Y N 15  
A   N7     N Y N 16  
A   C5     C Y N 17  
A   C6     C Y N 18  
A   N6     N N N 19  
A   N1     N Y N 20  
A   C2     C Y N 21  
A   N3     N Y N 22  
A   C4     C Y N 23  
A   HOP3   H N N 24  
A   HOP2   H N N 25  
A   "H5'"  H N N 26  
A   "H5''" H N N 27  
A   "H4'"  H N N 28  
A   "H3'"  H N N 29  
A   "HO3'" H N N 30  
A   "H2'"  H N N 31  
A   "HO2'" H N N 32  
A   "H1'"  H N N 33  
A   H8     H N N 34  
A   H61    H N N 35  
A   H62    H N N 36  
A   H2     H N N 37  
ALA N      N N N 38  
ALA CA     C N S 39  
ALA C      C N N 40  
ALA O      O N N 41  
ALA CB     C N N 42  
ALA OXT    O N N 43  
ALA H      H N N 44  
ALA H2     H N N 45  
ALA HA     H N N 46  
ALA HB1    H N N 47  
ALA HB2    H N N 48  
ALA HB3    H N N 49  
ALA HXT    H N N 50  
ARG N      N N N 51  
ARG CA     C N S 52  
ARG C      C N N 53  
ARG O      O N N 54  
ARG CB     C N N 55  
ARG CG     C N N 56  
ARG CD     C N N 57  
ARG NE     N N N 58  
ARG CZ     C N N 59  
ARG NH1    N N N 60  
ARG NH2    N N N 61  
ARG OXT    O N N 62  
ARG H      H N N 63  
ARG H2     H N N 64  
ARG HA     H N N 65  
ARG HB2    H N N 66  
ARG HB3    H N N 67  
ARG HG2    H N N 68  
ARG HG3    H N N 69  
ARG HD2    H N N 70  
ARG HD3    H N N 71  
ARG HE     H N N 72  
ARG HH11   H N N 73  
ARG HH12   H N N 74  
ARG HH21   H N N 75  
ARG HH22   H N N 76  
ARG HXT    H N N 77  
ASN N      N N N 78  
ASN CA     C N S 79  
ASN C      C N N 80  
ASN O      O N N 81  
ASN CB     C N N 82  
ASN CG     C N N 83  
ASN OD1    O N N 84  
ASN ND2    N N N 85  
ASN OXT    O N N 86  
ASN H      H N N 87  
ASN H2     H N N 88  
ASN HA     H N N 89  
ASN HB2    H N N 90  
ASN HB3    H N N 91  
ASN HD21   H N N 92  
ASN HD22   H N N 93  
ASN HXT    H N N 94  
ASP N      N N N 95  
ASP CA     C N S 96  
ASP C      C N N 97  
ASP O      O N N 98  
ASP CB     C N N 99  
ASP CG     C N N 100 
ASP OD1    O N N 101 
ASP OD2    O N N 102 
ASP OXT    O N N 103 
ASP H      H N N 104 
ASP H2     H N N 105 
ASP HA     H N N 106 
ASP HB2    H N N 107 
ASP HB3    H N N 108 
ASP HD2    H N N 109 
ASP HXT    H N N 110 
C   OP3    O N N 111 
C   P      P N N 112 
C   OP1    O N N 113 
C   OP2    O N N 114 
C   "O5'"  O N N 115 
C   "C5'"  C N N 116 
C   "C4'"  C N R 117 
C   "O4'"  O N N 118 
C   "C3'"  C N S 119 
C   "O3'"  O N N 120 
C   "C2'"  C N R 121 
C   "O2'"  O N N 122 
C   "C1'"  C N R 123 
C   N1     N N N 124 
C   C2     C N N 125 
C   O2     O N N 126 
C   N3     N N N 127 
C   C4     C N N 128 
C   N4     N N N 129 
C   C5     C N N 130 
C   C6     C N N 131 
C   HOP3   H N N 132 
C   HOP2   H N N 133 
C   "H5'"  H N N 134 
C   "H5''" H N N 135 
C   "H4'"  H N N 136 
C   "H3'"  H N N 137 
C   "HO3'" H N N 138 
C   "H2'"  H N N 139 
C   "HO2'" H N N 140 
C   "H1'"  H N N 141 
C   H41    H N N 142 
C   H42    H N N 143 
C   H5     H N N 144 
C   H6     H N N 145 
CYS N      N N N 146 
CYS CA     C N R 147 
CYS C      C N N 148 
CYS O      O N N 149 
CYS CB     C N N 150 
CYS SG     S N N 151 
CYS OXT    O N N 152 
CYS H      H N N 153 
CYS H2     H N N 154 
CYS HA     H N N 155 
CYS HB2    H N N 156 
CYS HB3    H N N 157 
CYS HG     H N N 158 
CYS HXT    H N N 159 
DA  OP3    O N N 160 
DA  P      P N N 161 
DA  OP1    O N N 162 
DA  OP2    O N N 163 
DA  "O5'"  O N N 164 
DA  "C5'"  C N N 165 
DA  "C4'"  C N R 166 
DA  "O4'"  O N N 167 
DA  "C3'"  C N S 168 
DA  "O3'"  O N N 169 
DA  "C2'"  C N N 170 
DA  "C1'"  C N R 171 
DA  N9     N Y N 172 
DA  C8     C Y N 173 
DA  N7     N Y N 174 
DA  C5     C Y N 175 
DA  C6     C Y N 176 
DA  N6     N N N 177 
DA  N1     N Y N 178 
DA  C2     C Y N 179 
DA  N3     N Y N 180 
DA  C4     C Y N 181 
DA  HOP3   H N N 182 
DA  HOP2   H N N 183 
DA  "H5'"  H N N 184 
DA  "H5''" H N N 185 
DA  "H4'"  H N N 186 
DA  "H3'"  H N N 187 
DA  "HO3'" H N N 188 
DA  "H2'"  H N N 189 
DA  "H2''" H N N 190 
DA  "H1'"  H N N 191 
DA  H8     H N N 192 
DA  H61    H N N 193 
DA  H62    H N N 194 
DA  H2     H N N 195 
DC  OP3    O N N 196 
DC  P      P N N 197 
DC  OP1    O N N 198 
DC  OP2    O N N 199 
DC  "O5'"  O N N 200 
DC  "C5'"  C N N 201 
DC  "C4'"  C N R 202 
DC  "O4'"  O N N 203 
DC  "C3'"  C N S 204 
DC  "O3'"  O N N 205 
DC  "C2'"  C N N 206 
DC  "C1'"  C N R 207 
DC  N1     N N N 208 
DC  C2     C N N 209 
DC  O2     O N N 210 
DC  N3     N N N 211 
DC  C4     C N N 212 
DC  N4     N N N 213 
DC  C5     C N N 214 
DC  C6     C N N 215 
DC  HOP3   H N N 216 
DC  HOP2   H N N 217 
DC  "H5'"  H N N 218 
DC  "H5''" H N N 219 
DC  "H4'"  H N N 220 
DC  "H3'"  H N N 221 
DC  "HO3'" H N N 222 
DC  "H2'"  H N N 223 
DC  "H2''" H N N 224 
DC  "H1'"  H N N 225 
DC  H41    H N N 226 
DC  H42    H N N 227 
DC  H5     H N N 228 
DC  H6     H N N 229 
DG  OP3    O N N 230 
DG  P      P N N 231 
DG  OP1    O N N 232 
DG  OP2    O N N 233 
DG  "O5'"  O N N 234 
DG  "C5'"  C N N 235 
DG  "C4'"  C N R 236 
DG  "O4'"  O N N 237 
DG  "C3'"  C N S 238 
DG  "O3'"  O N N 239 
DG  "C2'"  C N N 240 
DG  "C1'"  C N R 241 
DG  N9     N Y N 242 
DG  C8     C Y N 243 
DG  N7     N Y N 244 
DG  C5     C Y N 245 
DG  C6     C N N 246 
DG  O6     O N N 247 
DG  N1     N N N 248 
DG  C2     C N N 249 
DG  N2     N N N 250 
DG  N3     N N N 251 
DG  C4     C Y N 252 
DG  HOP3   H N N 253 
DG  HOP2   H N N 254 
DG  "H5'"  H N N 255 
DG  "H5''" H N N 256 
DG  "H4'"  H N N 257 
DG  "H3'"  H N N 258 
DG  "HO3'" H N N 259 
DG  "H2'"  H N N 260 
DG  "H2''" H N N 261 
DG  "H1'"  H N N 262 
DG  H8     H N N 263 
DG  H1     H N N 264 
DG  H21    H N N 265 
DG  H22    H N N 266 
DT  OP3    O N N 267 
DT  P      P N N 268 
DT  OP1    O N N 269 
DT  OP2    O N N 270 
DT  "O5'"  O N N 271 
DT  "C5'"  C N N 272 
DT  "C4'"  C N R 273 
DT  "O4'"  O N N 274 
DT  "C3'"  C N S 275 
DT  "O3'"  O N N 276 
DT  "C2'"  C N N 277 
DT  "C1'"  C N R 278 
DT  N1     N N N 279 
DT  C2     C N N 280 
DT  O2     O N N 281 
DT  N3     N N N 282 
DT  C4     C N N 283 
DT  O4     O N N 284 
DT  C5     C N N 285 
DT  C7     C N N 286 
DT  C6     C N N 287 
DT  HOP3   H N N 288 
DT  HOP2   H N N 289 
DT  "H5'"  H N N 290 
DT  "H5''" H N N 291 
DT  "H4'"  H N N 292 
DT  "H3'"  H N N 293 
DT  "HO3'" H N N 294 
DT  "H2'"  H N N 295 
DT  "H2''" H N N 296 
DT  "H1'"  H N N 297 
DT  H3     H N N 298 
DT  H71    H N N 299 
DT  H72    H N N 300 
DT  H73    H N N 301 
DT  H6     H N N 302 
G   OP3    O N N 303 
G   P      P N N 304 
G   OP1    O N N 305 
G   OP2    O N N 306 
G   "O5'"  O N N 307 
G   "C5'"  C N N 308 
G   "C4'"  C N R 309 
G   "O4'"  O N N 310 
G   "C3'"  C N S 311 
G   "O3'"  O N N 312 
G   "C2'"  C N R 313 
G   "O2'"  O N N 314 
G   "C1'"  C N R 315 
G   N9     N Y N 316 
G   C8     C Y N 317 
G   N7     N Y N 318 
G   C5     C Y N 319 
G   C6     C N N 320 
G   O6     O N N 321 
G   N1     N N N 322 
G   C2     C N N 323 
G   N2     N N N 324 
G   N3     N N N 325 
G   C4     C Y N 326 
G   HOP3   H N N 327 
G   HOP2   H N N 328 
G   "H5'"  H N N 329 
G   "H5''" H N N 330 
G   "H4'"  H N N 331 
G   "H3'"  H N N 332 
G   "HO3'" H N N 333 
G   "H2'"  H N N 334 
G   "HO2'" H N N 335 
G   "H1'"  H N N 336 
G   H8     H N N 337 
G   H1     H N N 338 
G   H21    H N N 339 
G   H22    H N N 340 
GLN N      N N N 341 
GLN CA     C N S 342 
GLN C      C N N 343 
GLN O      O N N 344 
GLN CB     C N N 345 
GLN CG     C N N 346 
GLN CD     C N N 347 
GLN OE1    O N N 348 
GLN NE2    N N N 349 
GLN OXT    O N N 350 
GLN H      H N N 351 
GLN H2     H N N 352 
GLN HA     H N N 353 
GLN HB2    H N N 354 
GLN HB3    H N N 355 
GLN HG2    H N N 356 
GLN HG3    H N N 357 
GLN HE21   H N N 358 
GLN HE22   H N N 359 
GLN HXT    H N N 360 
GLU N      N N N 361 
GLU CA     C N S 362 
GLU C      C N N 363 
GLU O      O N N 364 
GLU CB     C N N 365 
GLU CG     C N N 366 
GLU CD     C N N 367 
GLU OE1    O N N 368 
GLU OE2    O N N 369 
GLU OXT    O N N 370 
GLU H      H N N 371 
GLU H2     H N N 372 
GLU HA     H N N 373 
GLU HB2    H N N 374 
GLU HB3    H N N 375 
GLU HG2    H N N 376 
GLU HG3    H N N 377 
GLU HE2    H N N 378 
GLU HXT    H N N 379 
GLY N      N N N 380 
GLY CA     C N N 381 
GLY C      C N N 382 
GLY O      O N N 383 
GLY OXT    O N N 384 
GLY H      H N N 385 
GLY H2     H N N 386 
GLY HA2    H N N 387 
GLY HA3    H N N 388 
GLY HXT    H N N 389 
HIS N      N N N 390 
HIS CA     C N S 391 
HIS C      C N N 392 
HIS O      O N N 393 
HIS CB     C N N 394 
HIS CG     C Y N 395 
HIS ND1    N Y N 396 
HIS CD2    C Y N 397 
HIS CE1    C Y N 398 
HIS NE2    N Y N 399 
HIS OXT    O N N 400 
HIS H      H N N 401 
HIS H2     H N N 402 
HIS HA     H N N 403 
HIS HB2    H N N 404 
HIS HB3    H N N 405 
HIS HD1    H N N 406 
HIS HD2    H N N 407 
HIS HE1    H N N 408 
HIS HE2    H N N 409 
HIS HXT    H N N 410 
ILE N      N N N 411 
ILE CA     C N S 412 
ILE C      C N N 413 
ILE O      O N N 414 
ILE CB     C N S 415 
ILE CG1    C N N 416 
ILE CG2    C N N 417 
ILE CD1    C N N 418 
ILE OXT    O N N 419 
ILE H      H N N 420 
ILE H2     H N N 421 
ILE HA     H N N 422 
ILE HB     H N N 423 
ILE HG12   H N N 424 
ILE HG13   H N N 425 
ILE HG21   H N N 426 
ILE HG22   H N N 427 
ILE HG23   H N N 428 
ILE HD11   H N N 429 
ILE HD12   H N N 430 
ILE HD13   H N N 431 
ILE HXT    H N N 432 
LEU N      N N N 433 
LEU CA     C N S 434 
LEU C      C N N 435 
LEU O      O N N 436 
LEU CB     C N N 437 
LEU CG     C N N 438 
LEU CD1    C N N 439 
LEU CD2    C N N 440 
LEU OXT    O N N 441 
LEU H      H N N 442 
LEU H2     H N N 443 
LEU HA     H N N 444 
LEU HB2    H N N 445 
LEU HB3    H N N 446 
LEU HG     H N N 447 
LEU HD11   H N N 448 
LEU HD12   H N N 449 
LEU HD13   H N N 450 
LEU HD21   H N N 451 
LEU HD22   H N N 452 
LEU HD23   H N N 453 
LEU HXT    H N N 454 
LYS N      N N N 455 
LYS CA     C N S 456 
LYS C      C N N 457 
LYS O      O N N 458 
LYS CB     C N N 459 
LYS CG     C N N 460 
LYS CD     C N N 461 
LYS CE     C N N 462 
LYS NZ     N N N 463 
LYS OXT    O N N 464 
LYS H      H N N 465 
LYS H2     H N N 466 
LYS HA     H N N 467 
LYS HB2    H N N 468 
LYS HB3    H N N 469 
LYS HG2    H N N 470 
LYS HG3    H N N 471 
LYS HD2    H N N 472 
LYS HD3    H N N 473 
LYS HE2    H N N 474 
LYS HE3    H N N 475 
LYS HZ1    H N N 476 
LYS HZ2    H N N 477 
LYS HZ3    H N N 478 
LYS HXT    H N N 479 
MET N      N N N 480 
MET CA     C N S 481 
MET C      C N N 482 
MET O      O N N 483 
MET CB     C N N 484 
MET CG     C N N 485 
MET SD     S N N 486 
MET CE     C N N 487 
MET OXT    O N N 488 
MET H      H N N 489 
MET H2     H N N 490 
MET HA     H N N 491 
MET HB2    H N N 492 
MET HB3    H N N 493 
MET HG2    H N N 494 
MET HG3    H N N 495 
MET HE1    H N N 496 
MET HE2    H N N 497 
MET HE3    H N N 498 
MET HXT    H N N 499 
PHE N      N N N 500 
PHE CA     C N S 501 
PHE C      C N N 502 
PHE O      O N N 503 
PHE CB     C N N 504 
PHE CG     C Y N 505 
PHE CD1    C Y N 506 
PHE CD2    C Y N 507 
PHE CE1    C Y N 508 
PHE CE2    C Y N 509 
PHE CZ     C Y N 510 
PHE OXT    O N N 511 
PHE H      H N N 512 
PHE H2     H N N 513 
PHE HA     H N N 514 
PHE HB2    H N N 515 
PHE HB3    H N N 516 
PHE HD1    H N N 517 
PHE HD2    H N N 518 
PHE HE1    H N N 519 
PHE HE2    H N N 520 
PHE HZ     H N N 521 
PHE HXT    H N N 522 
PRO N      N N N 523 
PRO CA     C N S 524 
PRO C      C N N 525 
PRO O      O N N 526 
PRO CB     C N N 527 
PRO CG     C N N 528 
PRO CD     C N N 529 
PRO OXT    O N N 530 
PRO H      H N N 531 
PRO HA     H N N 532 
PRO HB2    H N N 533 
PRO HB3    H N N 534 
PRO HG2    H N N 535 
PRO HG3    H N N 536 
PRO HD2    H N N 537 
PRO HD3    H N N 538 
PRO HXT    H N N 539 
SER N      N N N 540 
SER CA     C N S 541 
SER C      C N N 542 
SER O      O N N 543 
SER CB     C N N 544 
SER OG     O N N 545 
SER OXT    O N N 546 
SER H      H N N 547 
SER H2     H N N 548 
SER HA     H N N 549 
SER HB2    H N N 550 
SER HB3    H N N 551 
SER HG     H N N 552 
SER HXT    H N N 553 
THR N      N N N 554 
THR CA     C N S 555 
THR C      C N N 556 
THR O      O N N 557 
THR CB     C N R 558 
THR OG1    O N N 559 
THR CG2    C N N 560 
THR OXT    O N N 561 
THR H      H N N 562 
THR H2     H N N 563 
THR HA     H N N 564 
THR HB     H N N 565 
THR HG1    H N N 566 
THR HG21   H N N 567 
THR HG22   H N N 568 
THR HG23   H N N 569 
THR HXT    H N N 570 
TRP N      N N N 571 
TRP CA     C N S 572 
TRP C      C N N 573 
TRP O      O N N 574 
TRP CB     C N N 575 
TRP CG     C Y N 576 
TRP CD1    C Y N 577 
TRP CD2    C Y N 578 
TRP NE1    N Y N 579 
TRP CE2    C Y N 580 
TRP CE3    C Y N 581 
TRP CZ2    C Y N 582 
TRP CZ3    C Y N 583 
TRP CH2    C Y N 584 
TRP OXT    O N N 585 
TRP H      H N N 586 
TRP H2     H N N 587 
TRP HA     H N N 588 
TRP HB2    H N N 589 
TRP HB3    H N N 590 
TRP HD1    H N N 591 
TRP HE1    H N N 592 
TRP HE3    H N N 593 
TRP HZ2    H N N 594 
TRP HZ3    H N N 595 
TRP HH2    H N N 596 
TRP HXT    H N N 597 
TYR N      N N N 598 
TYR CA     C N S 599 
TYR C      C N N 600 
TYR O      O N N 601 
TYR CB     C N N 602 
TYR CG     C Y N 603 
TYR CD1    C Y N 604 
TYR CD2    C Y N 605 
TYR CE1    C Y N 606 
TYR CE2    C Y N 607 
TYR CZ     C Y N 608 
TYR OH     O N N 609 
TYR OXT    O N N 610 
TYR H      H N N 611 
TYR H2     H N N 612 
TYR HA     H N N 613 
TYR HB2    H N N 614 
TYR HB3    H N N 615 
TYR HD1    H N N 616 
TYR HD2    H N N 617 
TYR HE1    H N N 618 
TYR HE2    H N N 619 
TYR HH     H N N 620 
TYR HXT    H N N 621 
U   OP3    O N N 622 
U   P      P N N 623 
U   OP1    O N N 624 
U   OP2    O N N 625 
U   "O5'"  O N N 626 
U   "C5'"  C N N 627 
U   "C4'"  C N R 628 
U   "O4'"  O N N 629 
U   "C3'"  C N S 630 
U   "O3'"  O N N 631 
U   "C2'"  C N R 632 
U   "O2'"  O N N 633 
U   "C1'"  C N R 634 
U   N1     N N N 635 
U   C2     C N N 636 
U   O2     O N N 637 
U   N3     N N N 638 
U   C4     C N N 639 
U   O4     O N N 640 
U   C5     C N N 641 
U   C6     C N N 642 
U   HOP3   H N N 643 
U   HOP2   H N N 644 
U   "H5'"  H N N 645 
U   "H5''" H N N 646 
U   "H4'"  H N N 647 
U   "H3'"  H N N 648 
U   "HO3'" H N N 649 
U   "H2'"  H N N 650 
U   "HO2'" H N N 651 
U   "H1'"  H N N 652 
U   H3     H N N 653 
U   H5     H N N 654 
U   H6     H N N 655 
VAL N      N N N 656 
VAL CA     C N S 657 
VAL C      C N N 658 
VAL O      O N N 659 
VAL CB     C N N 660 
VAL CG1    C N N 661 
VAL CG2    C N N 662 
VAL OXT    O N N 663 
VAL H      H N N 664 
VAL H2     H N N 665 
VAL HA     H N N 666 
VAL HB     H N N 667 
VAL HG11   H N N 668 
VAL HG12   H N N 669 
VAL HG13   H N N 670 
VAL HG21   H N N 671 
VAL HG22   H N N 672 
VAL HG23   H N N 673 
VAL HXT    H N N 674 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A   OP3   P      sing N N 1   
A   OP3   HOP3   sing N N 2   
A   P     OP1    doub N N 3   
A   P     OP2    sing N N 4   
A   P     "O5'"  sing N N 5   
A   OP2   HOP2   sing N N 6   
A   "O5'" "C5'"  sing N N 7   
A   "C5'" "C4'"  sing N N 8   
A   "C5'" "H5'"  sing N N 9   
A   "C5'" "H5''" sing N N 10  
A   "C4'" "O4'"  sing N N 11  
A   "C4'" "C3'"  sing N N 12  
A   "C4'" "H4'"  sing N N 13  
A   "O4'" "C1'"  sing N N 14  
A   "C3'" "O3'"  sing N N 15  
A   "C3'" "C2'"  sing N N 16  
A   "C3'" "H3'"  sing N N 17  
A   "O3'" "HO3'" sing N N 18  
A   "C2'" "O2'"  sing N N 19  
A   "C2'" "C1'"  sing N N 20  
A   "C2'" "H2'"  sing N N 21  
A   "O2'" "HO2'" sing N N 22  
A   "C1'" N9     sing N N 23  
A   "C1'" "H1'"  sing N N 24  
A   N9    C8     sing Y N 25  
A   N9    C4     sing Y N 26  
A   C8    N7     doub Y N 27  
A   C8    H8     sing N N 28  
A   N7    C5     sing Y N 29  
A   C5    C6     sing Y N 30  
A   C5    C4     doub Y N 31  
A   C6    N6     sing N N 32  
A   C6    N1     doub Y N 33  
A   N6    H61    sing N N 34  
A   N6    H62    sing N N 35  
A   N1    C2     sing Y N 36  
A   C2    N3     doub Y N 37  
A   C2    H2     sing N N 38  
A   N3    C4     sing Y N 39  
ALA N     CA     sing N N 40  
ALA N     H      sing N N 41  
ALA N     H2     sing N N 42  
ALA CA    C      sing N N 43  
ALA CA    CB     sing N N 44  
ALA CA    HA     sing N N 45  
ALA C     O      doub N N 46  
ALA C     OXT    sing N N 47  
ALA CB    HB1    sing N N 48  
ALA CB    HB2    sing N N 49  
ALA CB    HB3    sing N N 50  
ALA OXT   HXT    sing N N 51  
ARG N     CA     sing N N 52  
ARG N     H      sing N N 53  
ARG N     H2     sing N N 54  
ARG CA    C      sing N N 55  
ARG CA    CB     sing N N 56  
ARG CA    HA     sing N N 57  
ARG C     O      doub N N 58  
ARG C     OXT    sing N N 59  
ARG CB    CG     sing N N 60  
ARG CB    HB2    sing N N 61  
ARG CB    HB3    sing N N 62  
ARG CG    CD     sing N N 63  
ARG CG    HG2    sing N N 64  
ARG CG    HG3    sing N N 65  
ARG CD    NE     sing N N 66  
ARG CD    HD2    sing N N 67  
ARG CD    HD3    sing N N 68  
ARG NE    CZ     sing N N 69  
ARG NE    HE     sing N N 70  
ARG CZ    NH1    sing N N 71  
ARG CZ    NH2    doub N N 72  
ARG NH1   HH11   sing N N 73  
ARG NH1   HH12   sing N N 74  
ARG NH2   HH21   sing N N 75  
ARG NH2   HH22   sing N N 76  
ARG OXT   HXT    sing N N 77  
ASN N     CA     sing N N 78  
ASN N     H      sing N N 79  
ASN N     H2     sing N N 80  
ASN CA    C      sing N N 81  
ASN CA    CB     sing N N 82  
ASN CA    HA     sing N N 83  
ASN C     O      doub N N 84  
ASN C     OXT    sing N N 85  
ASN CB    CG     sing N N 86  
ASN CB    HB2    sing N N 87  
ASN CB    HB3    sing N N 88  
ASN CG    OD1    doub N N 89  
ASN CG    ND2    sing N N 90  
ASN ND2   HD21   sing N N 91  
ASN ND2   HD22   sing N N 92  
ASN OXT   HXT    sing N N 93  
ASP N     CA     sing N N 94  
ASP N     H      sing N N 95  
ASP N     H2     sing N N 96  
ASP CA    C      sing N N 97  
ASP CA    CB     sing N N 98  
ASP CA    HA     sing N N 99  
ASP C     O      doub N N 100 
ASP C     OXT    sing N N 101 
ASP CB    CG     sing N N 102 
ASP CB    HB2    sing N N 103 
ASP CB    HB3    sing N N 104 
ASP CG    OD1    doub N N 105 
ASP CG    OD2    sing N N 106 
ASP OD2   HD2    sing N N 107 
ASP OXT   HXT    sing N N 108 
C   OP3   P      sing N N 109 
C   OP3   HOP3   sing N N 110 
C   P     OP1    doub N N 111 
C   P     OP2    sing N N 112 
C   P     "O5'"  sing N N 113 
C   OP2   HOP2   sing N N 114 
C   "O5'" "C5'"  sing N N 115 
C   "C5'" "C4'"  sing N N 116 
C   "C5'" "H5'"  sing N N 117 
C   "C5'" "H5''" sing N N 118 
C   "C4'" "O4'"  sing N N 119 
C   "C4'" "C3'"  sing N N 120 
C   "C4'" "H4'"  sing N N 121 
C   "O4'" "C1'"  sing N N 122 
C   "C3'" "O3'"  sing N N 123 
C   "C3'" "C2'"  sing N N 124 
C   "C3'" "H3'"  sing N N 125 
C   "O3'" "HO3'" sing N N 126 
C   "C2'" "O2'"  sing N N 127 
C   "C2'" "C1'"  sing N N 128 
C   "C2'" "H2'"  sing N N 129 
C   "O2'" "HO2'" sing N N 130 
C   "C1'" N1     sing N N 131 
C   "C1'" "H1'"  sing N N 132 
C   N1    C2     sing N N 133 
C   N1    C6     sing N N 134 
C   C2    O2     doub N N 135 
C   C2    N3     sing N N 136 
C   N3    C4     doub N N 137 
C   C4    N4     sing N N 138 
C   C4    C5     sing N N 139 
C   N4    H41    sing N N 140 
C   N4    H42    sing N N 141 
C   C5    C6     doub N N 142 
C   C5    H5     sing N N 143 
C   C6    H6     sing N N 144 
CYS N     CA     sing N N 145 
CYS N     H      sing N N 146 
CYS N     H2     sing N N 147 
CYS CA    C      sing N N 148 
CYS CA    CB     sing N N 149 
CYS CA    HA     sing N N 150 
CYS C     O      doub N N 151 
CYS C     OXT    sing N N 152 
CYS CB    SG     sing N N 153 
CYS CB    HB2    sing N N 154 
CYS CB    HB3    sing N N 155 
CYS SG    HG     sing N N 156 
CYS OXT   HXT    sing N N 157 
DA  OP3   P      sing N N 158 
DA  OP3   HOP3   sing N N 159 
DA  P     OP1    doub N N 160 
DA  P     OP2    sing N N 161 
DA  P     "O5'"  sing N N 162 
DA  OP2   HOP2   sing N N 163 
DA  "O5'" "C5'"  sing N N 164 
DA  "C5'" "C4'"  sing N N 165 
DA  "C5'" "H5'"  sing N N 166 
DA  "C5'" "H5''" sing N N 167 
DA  "C4'" "O4'"  sing N N 168 
DA  "C4'" "C3'"  sing N N 169 
DA  "C4'" "H4'"  sing N N 170 
DA  "O4'" "C1'"  sing N N 171 
DA  "C3'" "O3'"  sing N N 172 
DA  "C3'" "C2'"  sing N N 173 
DA  "C3'" "H3'"  sing N N 174 
DA  "O3'" "HO3'" sing N N 175 
DA  "C2'" "C1'"  sing N N 176 
DA  "C2'" "H2'"  sing N N 177 
DA  "C2'" "H2''" sing N N 178 
DA  "C1'" N9     sing N N 179 
DA  "C1'" "H1'"  sing N N 180 
DA  N9    C8     sing Y N 181 
DA  N9    C4     sing Y N 182 
DA  C8    N7     doub Y N 183 
DA  C8    H8     sing N N 184 
DA  N7    C5     sing Y N 185 
DA  C5    C6     sing Y N 186 
DA  C5    C4     doub Y N 187 
DA  C6    N6     sing N N 188 
DA  C6    N1     doub Y N 189 
DA  N6    H61    sing N N 190 
DA  N6    H62    sing N N 191 
DA  N1    C2     sing Y N 192 
DA  C2    N3     doub Y N 193 
DA  C2    H2     sing N N 194 
DA  N3    C4     sing Y N 195 
DC  OP3   P      sing N N 196 
DC  OP3   HOP3   sing N N 197 
DC  P     OP1    doub N N 198 
DC  P     OP2    sing N N 199 
DC  P     "O5'"  sing N N 200 
DC  OP2   HOP2   sing N N 201 
DC  "O5'" "C5'"  sing N N 202 
DC  "C5'" "C4'"  sing N N 203 
DC  "C5'" "H5'"  sing N N 204 
DC  "C5'" "H5''" sing N N 205 
DC  "C4'" "O4'"  sing N N 206 
DC  "C4'" "C3'"  sing N N 207 
DC  "C4'" "H4'"  sing N N 208 
DC  "O4'" "C1'"  sing N N 209 
DC  "C3'" "O3'"  sing N N 210 
DC  "C3'" "C2'"  sing N N 211 
DC  "C3'" "H3'"  sing N N 212 
DC  "O3'" "HO3'" sing N N 213 
DC  "C2'" "C1'"  sing N N 214 
DC  "C2'" "H2'"  sing N N 215 
DC  "C2'" "H2''" sing N N 216 
DC  "C1'" N1     sing N N 217 
DC  "C1'" "H1'"  sing N N 218 
DC  N1    C2     sing N N 219 
DC  N1    C6     sing N N 220 
DC  C2    O2     doub N N 221 
DC  C2    N3     sing N N 222 
DC  N3    C4     doub N N 223 
DC  C4    N4     sing N N 224 
DC  C4    C5     sing N N 225 
DC  N4    H41    sing N N 226 
DC  N4    H42    sing N N 227 
DC  C5    C6     doub N N 228 
DC  C5    H5     sing N N 229 
DC  C6    H6     sing N N 230 
DG  OP3   P      sing N N 231 
DG  OP3   HOP3   sing N N 232 
DG  P     OP1    doub N N 233 
DG  P     OP2    sing N N 234 
DG  P     "O5'"  sing N N 235 
DG  OP2   HOP2   sing N N 236 
DG  "O5'" "C5'"  sing N N 237 
DG  "C5'" "C4'"  sing N N 238 
DG  "C5'" "H5'"  sing N N 239 
DG  "C5'" "H5''" sing N N 240 
DG  "C4'" "O4'"  sing N N 241 
DG  "C4'" "C3'"  sing N N 242 
DG  "C4'" "H4'"  sing N N 243 
DG  "O4'" "C1'"  sing N N 244 
DG  "C3'" "O3'"  sing N N 245 
DG  "C3'" "C2'"  sing N N 246 
DG  "C3'" "H3'"  sing N N 247 
DG  "O3'" "HO3'" sing N N 248 
DG  "C2'" "C1'"  sing N N 249 
DG  "C2'" "H2'"  sing N N 250 
DG  "C2'" "H2''" sing N N 251 
DG  "C1'" N9     sing N N 252 
DG  "C1'" "H1'"  sing N N 253 
DG  N9    C8     sing Y N 254 
DG  N9    C4     sing Y N 255 
DG  C8    N7     doub Y N 256 
DG  C8    H8     sing N N 257 
DG  N7    C5     sing Y N 258 
DG  C5    C6     sing N N 259 
DG  C5    C4     doub Y N 260 
DG  C6    O6     doub N N 261 
DG  C6    N1     sing N N 262 
DG  N1    C2     sing N N 263 
DG  N1    H1     sing N N 264 
DG  C2    N2     sing N N 265 
DG  C2    N3     doub N N 266 
DG  N2    H21    sing N N 267 
DG  N2    H22    sing N N 268 
DG  N3    C4     sing N N 269 
DT  OP3   P      sing N N 270 
DT  OP3   HOP3   sing N N 271 
DT  P     OP1    doub N N 272 
DT  P     OP2    sing N N 273 
DT  P     "O5'"  sing N N 274 
DT  OP2   HOP2   sing N N 275 
DT  "O5'" "C5'"  sing N N 276 
DT  "C5'" "C4'"  sing N N 277 
DT  "C5'" "H5'"  sing N N 278 
DT  "C5'" "H5''" sing N N 279 
DT  "C4'" "O4'"  sing N N 280 
DT  "C4'" "C3'"  sing N N 281 
DT  "C4'" "H4'"  sing N N 282 
DT  "O4'" "C1'"  sing N N 283 
DT  "C3'" "O3'"  sing N N 284 
DT  "C3'" "C2'"  sing N N 285 
DT  "C3'" "H3'"  sing N N 286 
DT  "O3'" "HO3'" sing N N 287 
DT  "C2'" "C1'"  sing N N 288 
DT  "C2'" "H2'"  sing N N 289 
DT  "C2'" "H2''" sing N N 290 
DT  "C1'" N1     sing N N 291 
DT  "C1'" "H1'"  sing N N 292 
DT  N1    C2     sing N N 293 
DT  N1    C6     sing N N 294 
DT  C2    O2     doub N N 295 
DT  C2    N3     sing N N 296 
DT  N3    C4     sing N N 297 
DT  N3    H3     sing N N 298 
DT  C4    O4     doub N N 299 
DT  C4    C5     sing N N 300 
DT  C5    C7     sing N N 301 
DT  C5    C6     doub N N 302 
DT  C7    H71    sing N N 303 
DT  C7    H72    sing N N 304 
DT  C7    H73    sing N N 305 
DT  C6    H6     sing N N 306 
G   OP3   P      sing N N 307 
G   OP3   HOP3   sing N N 308 
G   P     OP1    doub N N 309 
G   P     OP2    sing N N 310 
G   P     "O5'"  sing N N 311 
G   OP2   HOP2   sing N N 312 
G   "O5'" "C5'"  sing N N 313 
G   "C5'" "C4'"  sing N N 314 
G   "C5'" "H5'"  sing N N 315 
G   "C5'" "H5''" sing N N 316 
G   "C4'" "O4'"  sing N N 317 
G   "C4'" "C3'"  sing N N 318 
G   "C4'" "H4'"  sing N N 319 
G   "O4'" "C1'"  sing N N 320 
G   "C3'" "O3'"  sing N N 321 
G   "C3'" "C2'"  sing N N 322 
G   "C3'" "H3'"  sing N N 323 
G   "O3'" "HO3'" sing N N 324 
G   "C2'" "O2'"  sing N N 325 
G   "C2'" "C1'"  sing N N 326 
G   "C2'" "H2'"  sing N N 327 
G   "O2'" "HO2'" sing N N 328 
G   "C1'" N9     sing N N 329 
G   "C1'" "H1'"  sing N N 330 
G   N9    C8     sing Y N 331 
G   N9    C4     sing Y N 332 
G   C8    N7     doub Y N 333 
G   C8    H8     sing N N 334 
G   N7    C5     sing Y N 335 
G   C5    C6     sing N N 336 
G   C5    C4     doub Y N 337 
G   C6    O6     doub N N 338 
G   C6    N1     sing N N 339 
G   N1    C2     sing N N 340 
G   N1    H1     sing N N 341 
G   C2    N2     sing N N 342 
G   C2    N3     doub N N 343 
G   N2    H21    sing N N 344 
G   N2    H22    sing N N 345 
G   N3    C4     sing N N 346 
GLN N     CA     sing N N 347 
GLN N     H      sing N N 348 
GLN N     H2     sing N N 349 
GLN CA    C      sing N N 350 
GLN CA    CB     sing N N 351 
GLN CA    HA     sing N N 352 
GLN C     O      doub N N 353 
GLN C     OXT    sing N N 354 
GLN CB    CG     sing N N 355 
GLN CB    HB2    sing N N 356 
GLN CB    HB3    sing N N 357 
GLN CG    CD     sing N N 358 
GLN CG    HG2    sing N N 359 
GLN CG    HG3    sing N N 360 
GLN CD    OE1    doub N N 361 
GLN CD    NE2    sing N N 362 
GLN NE2   HE21   sing N N 363 
GLN NE2   HE22   sing N N 364 
GLN OXT   HXT    sing N N 365 
GLU N     CA     sing N N 366 
GLU N     H      sing N N 367 
GLU N     H2     sing N N 368 
GLU CA    C      sing N N 369 
GLU CA    CB     sing N N 370 
GLU CA    HA     sing N N 371 
GLU C     O      doub N N 372 
GLU C     OXT    sing N N 373 
GLU CB    CG     sing N N 374 
GLU CB    HB2    sing N N 375 
GLU CB    HB3    sing N N 376 
GLU CG    CD     sing N N 377 
GLU CG    HG2    sing N N 378 
GLU CG    HG3    sing N N 379 
GLU CD    OE1    doub N N 380 
GLU CD    OE2    sing N N 381 
GLU OE2   HE2    sing N N 382 
GLU OXT   HXT    sing N N 383 
GLY N     CA     sing N N 384 
GLY N     H      sing N N 385 
GLY N     H2     sing N N 386 
GLY CA    C      sing N N 387 
GLY CA    HA2    sing N N 388 
GLY CA    HA3    sing N N 389 
GLY C     O      doub N N 390 
GLY C     OXT    sing N N 391 
GLY OXT   HXT    sing N N 392 
HIS N     CA     sing N N 393 
HIS N     H      sing N N 394 
HIS N     H2     sing N N 395 
HIS CA    C      sing N N 396 
HIS CA    CB     sing N N 397 
HIS CA    HA     sing N N 398 
HIS C     O      doub N N 399 
HIS C     OXT    sing N N 400 
HIS CB    CG     sing N N 401 
HIS CB    HB2    sing N N 402 
HIS CB    HB3    sing N N 403 
HIS CG    ND1    sing Y N 404 
HIS CG    CD2    doub Y N 405 
HIS ND1   CE1    doub Y N 406 
HIS ND1   HD1    sing N N 407 
HIS CD2   NE2    sing Y N 408 
HIS CD2   HD2    sing N N 409 
HIS CE1   NE2    sing Y N 410 
HIS CE1   HE1    sing N N 411 
HIS NE2   HE2    sing N N 412 
HIS OXT   HXT    sing N N 413 
ILE N     CA     sing N N 414 
ILE N     H      sing N N 415 
ILE N     H2     sing N N 416 
ILE CA    C      sing N N 417 
ILE CA    CB     sing N N 418 
ILE CA    HA     sing N N 419 
ILE C     O      doub N N 420 
ILE C     OXT    sing N N 421 
ILE CB    CG1    sing N N 422 
ILE CB    CG2    sing N N 423 
ILE CB    HB     sing N N 424 
ILE CG1   CD1    sing N N 425 
ILE CG1   HG12   sing N N 426 
ILE CG1   HG13   sing N N 427 
ILE CG2   HG21   sing N N 428 
ILE CG2   HG22   sing N N 429 
ILE CG2   HG23   sing N N 430 
ILE CD1   HD11   sing N N 431 
ILE CD1   HD12   sing N N 432 
ILE CD1   HD13   sing N N 433 
ILE OXT   HXT    sing N N 434 
LEU N     CA     sing N N 435 
LEU N     H      sing N N 436 
LEU N     H2     sing N N 437 
LEU CA    C      sing N N 438 
LEU CA    CB     sing N N 439 
LEU CA    HA     sing N N 440 
LEU C     O      doub N N 441 
LEU C     OXT    sing N N 442 
LEU CB    CG     sing N N 443 
LEU CB    HB2    sing N N 444 
LEU CB    HB3    sing N N 445 
LEU CG    CD1    sing N N 446 
LEU CG    CD2    sing N N 447 
LEU CG    HG     sing N N 448 
LEU CD1   HD11   sing N N 449 
LEU CD1   HD12   sing N N 450 
LEU CD1   HD13   sing N N 451 
LEU CD2   HD21   sing N N 452 
LEU CD2   HD22   sing N N 453 
LEU CD2   HD23   sing N N 454 
LEU OXT   HXT    sing N N 455 
LYS N     CA     sing N N 456 
LYS N     H      sing N N 457 
LYS N     H2     sing N N 458 
LYS CA    C      sing N N 459 
LYS CA    CB     sing N N 460 
LYS CA    HA     sing N N 461 
LYS C     O      doub N N 462 
LYS C     OXT    sing N N 463 
LYS CB    CG     sing N N 464 
LYS CB    HB2    sing N N 465 
LYS CB    HB3    sing N N 466 
LYS CG    CD     sing N N 467 
LYS CG    HG2    sing N N 468 
LYS CG    HG3    sing N N 469 
LYS CD    CE     sing N N 470 
LYS CD    HD2    sing N N 471 
LYS CD    HD3    sing N N 472 
LYS CE    NZ     sing N N 473 
LYS CE    HE2    sing N N 474 
LYS CE    HE3    sing N N 475 
LYS NZ    HZ1    sing N N 476 
LYS NZ    HZ2    sing N N 477 
LYS NZ    HZ3    sing N N 478 
LYS OXT   HXT    sing N N 479 
MET N     CA     sing N N 480 
MET N     H      sing N N 481 
MET N     H2     sing N N 482 
MET CA    C      sing N N 483 
MET CA    CB     sing N N 484 
MET CA    HA     sing N N 485 
MET C     O      doub N N 486 
MET C     OXT    sing N N 487 
MET CB    CG     sing N N 488 
MET CB    HB2    sing N N 489 
MET CB    HB3    sing N N 490 
MET CG    SD     sing N N 491 
MET CG    HG2    sing N N 492 
MET CG    HG3    sing N N 493 
MET SD    CE     sing N N 494 
MET CE    HE1    sing N N 495 
MET CE    HE2    sing N N 496 
MET CE    HE3    sing N N 497 
MET OXT   HXT    sing N N 498 
PHE N     CA     sing N N 499 
PHE N     H      sing N N 500 
PHE N     H2     sing N N 501 
PHE CA    C      sing N N 502 
PHE CA    CB     sing N N 503 
PHE CA    HA     sing N N 504 
PHE C     O      doub N N 505 
PHE C     OXT    sing N N 506 
PHE CB    CG     sing N N 507 
PHE CB    HB2    sing N N 508 
PHE CB    HB3    sing N N 509 
PHE CG    CD1    doub Y N 510 
PHE CG    CD2    sing Y N 511 
PHE CD1   CE1    sing Y N 512 
PHE CD1   HD1    sing N N 513 
PHE CD2   CE2    doub Y N 514 
PHE CD2   HD2    sing N N 515 
PHE CE1   CZ     doub Y N 516 
PHE CE1   HE1    sing N N 517 
PHE CE2   CZ     sing Y N 518 
PHE CE2   HE2    sing N N 519 
PHE CZ    HZ     sing N N 520 
PHE OXT   HXT    sing N N 521 
PRO N     CA     sing N N 522 
PRO N     CD     sing N N 523 
PRO N     H      sing N N 524 
PRO CA    C      sing N N 525 
PRO CA    CB     sing N N 526 
PRO CA    HA     sing N N 527 
PRO C     O      doub N N 528 
PRO C     OXT    sing N N 529 
PRO CB    CG     sing N N 530 
PRO CB    HB2    sing N N 531 
PRO CB    HB3    sing N N 532 
PRO CG    CD     sing N N 533 
PRO CG    HG2    sing N N 534 
PRO CG    HG3    sing N N 535 
PRO CD    HD2    sing N N 536 
PRO CD    HD3    sing N N 537 
PRO OXT   HXT    sing N N 538 
SER N     CA     sing N N 539 
SER N     H      sing N N 540 
SER N     H2     sing N N 541 
SER CA    C      sing N N 542 
SER CA    CB     sing N N 543 
SER CA    HA     sing N N 544 
SER C     O      doub N N 545 
SER C     OXT    sing N N 546 
SER CB    OG     sing N N 547 
SER CB    HB2    sing N N 548 
SER CB    HB3    sing N N 549 
SER OG    HG     sing N N 550 
SER OXT   HXT    sing N N 551 
THR N     CA     sing N N 552 
THR N     H      sing N N 553 
THR N     H2     sing N N 554 
THR CA    C      sing N N 555 
THR CA    CB     sing N N 556 
THR CA    HA     sing N N 557 
THR C     O      doub N N 558 
THR C     OXT    sing N N 559 
THR CB    OG1    sing N N 560 
THR CB    CG2    sing N N 561 
THR CB    HB     sing N N 562 
THR OG1   HG1    sing N N 563 
THR CG2   HG21   sing N N 564 
THR CG2   HG22   sing N N 565 
THR CG2   HG23   sing N N 566 
THR OXT   HXT    sing N N 567 
TRP N     CA     sing N N 568 
TRP N     H      sing N N 569 
TRP N     H2     sing N N 570 
TRP CA    C      sing N N 571 
TRP CA    CB     sing N N 572 
TRP CA    HA     sing N N 573 
TRP C     O      doub N N 574 
TRP C     OXT    sing N N 575 
TRP CB    CG     sing N N 576 
TRP CB    HB2    sing N N 577 
TRP CB    HB3    sing N N 578 
TRP CG    CD1    doub Y N 579 
TRP CG    CD2    sing Y N 580 
TRP CD1   NE1    sing Y N 581 
TRP CD1   HD1    sing N N 582 
TRP CD2   CE2    doub Y N 583 
TRP CD2   CE3    sing Y N 584 
TRP NE1   CE2    sing Y N 585 
TRP NE1   HE1    sing N N 586 
TRP CE2   CZ2    sing Y N 587 
TRP CE3   CZ3    doub Y N 588 
TRP CE3   HE3    sing N N 589 
TRP CZ2   CH2    doub Y N 590 
TRP CZ2   HZ2    sing N N 591 
TRP CZ3   CH2    sing Y N 592 
TRP CZ3   HZ3    sing N N 593 
TRP CH2   HH2    sing N N 594 
TRP OXT   HXT    sing N N 595 
TYR N     CA     sing N N 596 
TYR N     H      sing N N 597 
TYR N     H2     sing N N 598 
TYR CA    C      sing N N 599 
TYR CA    CB     sing N N 600 
TYR CA    HA     sing N N 601 
TYR C     O      doub N N 602 
TYR C     OXT    sing N N 603 
TYR CB    CG     sing N N 604 
TYR CB    HB2    sing N N 605 
TYR CB    HB3    sing N N 606 
TYR CG    CD1    doub Y N 607 
TYR CG    CD2    sing Y N 608 
TYR CD1   CE1    sing Y N 609 
TYR CD1   HD1    sing N N 610 
TYR CD2   CE2    doub Y N 611 
TYR CD2   HD2    sing N N 612 
TYR CE1   CZ     doub Y N 613 
TYR CE1   HE1    sing N N 614 
TYR CE2   CZ     sing Y N 615 
TYR CE2   HE2    sing N N 616 
TYR CZ    OH     sing N N 617 
TYR OH    HH     sing N N 618 
TYR OXT   HXT    sing N N 619 
U   OP3   P      sing N N 620 
U   OP3   HOP3   sing N N 621 
U   P     OP1    doub N N 622 
U   P     OP2    sing N N 623 
U   P     "O5'"  sing N N 624 
U   OP2   HOP2   sing N N 625 
U   "O5'" "C5'"  sing N N 626 
U   "C5'" "C4'"  sing N N 627 
U   "C5'" "H5'"  sing N N 628 
U   "C5'" "H5''" sing N N 629 
U   "C4'" "O4'"  sing N N 630 
U   "C4'" "C3'"  sing N N 631 
U   "C4'" "H4'"  sing N N 632 
U   "O4'" "C1'"  sing N N 633 
U   "C3'" "O3'"  sing N N 634 
U   "C3'" "C2'"  sing N N 635 
U   "C3'" "H3'"  sing N N 636 
U   "O3'" "HO3'" sing N N 637 
U   "C2'" "O2'"  sing N N 638 
U   "C2'" "C1'"  sing N N 639 
U   "C2'" "H2'"  sing N N 640 
U   "O2'" "HO2'" sing N N 641 
U   "C1'" N1     sing N N 642 
U   "C1'" "H1'"  sing N N 643 
U   N1    C2     sing N N 644 
U   N1    C6     sing N N 645 
U   C2    O2     doub N N 646 
U   C2    N3     sing N N 647 
U   N3    C4     sing N N 648 
U   N3    H3     sing N N 649 
U   C4    O4     doub N N 650 
U   C4    C5     sing N N 651 
U   C5    C6     doub N N 652 
U   C5    H5     sing N N 653 
U   C6    H6     sing N N 654 
VAL N     CA     sing N N 655 
VAL N     H      sing N N 656 
VAL N     H2     sing N N 657 
VAL CA    C      sing N N 658 
VAL CA    CB     sing N N 659 
VAL CA    HA     sing N N 660 
VAL C     O      doub N N 661 
VAL C     OXT    sing N N 662 
VAL CB    CG1    sing N N 663 
VAL CB    CG2    sing N N 664 
VAL CB    HB     sing N N 665 
VAL CG1   HG11   sing N N 666 
VAL CG1   HG12   sing N N 667 
VAL CG1   HG13   sing N N 668 
VAL CG2   HG21   sing N N 669 
VAL CG2   HG22   sing N N 670 
VAL CG2   HG23   sing N N 671 
VAL OXT   HXT    sing N N 672 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-10-17 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8WS9 
_em_admin.last_update        2025-06-18 
_em_admin.map_release_date   2025-04-16 
_em_admin.title              'Cryo-EM mini structure of Cas12-1 with 5 nt complementary heteroduplex' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          12908 
_em_entity_assembly_naturalsource.organism             'unclassified sequences' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          469008 
_em_entity_assembly_recombinant.organism             'Escherichia coli BL21(DE3)' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ?      ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ?      ? 
MASKING                         ? 3  ? ? ? ?      ? 
'CTF CORRECTION'                ? 4  1 ? ? ?      ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ?      ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ?      ? 
'MODEL FITTING'                 ? 7  ? ? ? ?      ? 
'MODEL REFINEMENT'              ? 8  ? ? ? PHENIX ? 
OTHER                           ? 9  ? ? ? ?      ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ?      ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ?      ? 
CLASSIFICATION                  ? 12 1 ? ? ?      ? 
RECONSTRUCTION                  ? 13 1 ? ? ?      ? 
'VOLUME SELECTION'              ? 14 1 1 1 ?      ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ?      ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ?      ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ?      ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ?      ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ?      ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_ndb_struct_conf_na.entry_id 
_ndb_struct_conf_na.feature 
8WS9 'double helix'        
8WS9 'a-form double helix' 
8WS9 'b-form double helix' 
# 
loop_
_ndb_struct_na_base_pair.model_number 
_ndb_struct_na_base_pair.i_label_asym_id 
_ndb_struct_na_base_pair.i_label_comp_id 
_ndb_struct_na_base_pair.i_label_seq_id 
_ndb_struct_na_base_pair.i_symmetry 
_ndb_struct_na_base_pair.j_label_asym_id 
_ndb_struct_na_base_pair.j_label_comp_id 
_ndb_struct_na_base_pair.j_label_seq_id 
_ndb_struct_na_base_pair.j_symmetry 
_ndb_struct_na_base_pair.shear 
_ndb_struct_na_base_pair.stretch 
_ndb_struct_na_base_pair.stagger 
_ndb_struct_na_base_pair.buckle 
_ndb_struct_na_base_pair.propeller 
_ndb_struct_na_base_pair.opening 
_ndb_struct_na_base_pair.pair_number 
_ndb_struct_na_base_pair.pair_name 
_ndb_struct_na_base_pair.i_auth_asym_id 
_ndb_struct_na_base_pair.i_auth_seq_id 
_ndb_struct_na_base_pair.i_PDB_ins_code 
_ndb_struct_na_base_pair.j_auth_asym_id 
_ndb_struct_na_base_pair.j_auth_seq_id 
_ndb_struct_na_base_pair.j_PDB_ins_code 
_ndb_struct_na_base_pair.hbond_type_28 
_ndb_struct_na_base_pair.hbond_type_12 
1 B G  10 1_555 B A  25 1_555 -0.294 0.946  -2.305 -25.195 -1.510  -31.735 1  B_G-16:A-1_B B -16 ? B -1 ? 8  1 
1 B C  11 1_555 B G  24 1_555 0.149  -0.294 -0.949 -12.725 8.671   -2.324  2  B_C-15:G-2_B B -15 ? B -2 ? 19 1 
1 B U  12 1_555 B A  23 1_555 -0.062 -0.071 0.273  -4.109  0.554   0.804   3  B_U-14:A-3_B B -14 ? B -3 ? 20 1 
1 B C  13 1_555 B G  22 1_555 1.917  0.302  -0.003 0.121   -13.641 6.316   4  B_C-13:G-4_B B -13 ? B -4 ? ?  1 
1 B G  15 1_555 B C  21 1_555 -0.014 -0.533 1.535  4.512   8.077   8.241   5  B_G-11:C-5_B B -11 ? B -5 ? 19 1 
1 B U  27 1_555 C DA 32 1_555 5.319  0.152  -0.395 -28.266 16.043  9.798   6  B_U1:DA-1_C  B 1   ? C -1 ? ?  ? 
1 B C  29 1_555 C DG 31 1_555 2.345  0.231  0.946  4.464   5.292   35.776  7  B_C3:DG-2_C  B 3   ? C -2 ? ?  1 
1 C DG 33 1_555 D DT 9  1_555 -1.105 -1.170 -1.818 -2.940  16.420  -22.012 8  C_DG0:DT-1_D C 0   ? D -1 ? 28 1 
1 C DA 35 1_555 D DT 8  1_555 0.115  -0.226 0.982  8.243   -0.689  -0.359  9  C_DA2:DT-2_D C 2   ? D -2 ? 20 1 
1 C DT 36 1_555 D DA 7  1_555 -0.106 -0.153 0.409  9.332   -5.150  0.457   10 C_DT3:DA-3_D C 3   ? D -3 ? 20 1 
1 C DT 37 1_555 D DA 6  1_555 0.793  0.280  -0.230 9.024   -12.254 12.534  11 C_DT4:DA-4_D C 4   ? D -4 ? ?  1 
1 C DG 38 1_555 D DC 5  1_555 -0.180 -0.153 -0.222 -1.276  -0.502  0.643   12 C_DG5:DC-5_D C 5   ? D -5 ? 19 1 
1 C DG 39 1_555 D DC 4  1_555 -0.146 -0.351 -1.156 -0.914  -0.578  0.937   13 C_DG6:DC-6_D C 6   ? D -6 ? 19 1 
1 C DC 41 1_555 D DG 2  1_555 0.166  -0.311 1.021  3.102   -0.716  0.583   14 C_DC8:DG-8_D C 8   ? D -8 ? 19 1 
1 C DA 42 1_555 D DT 1  1_555 0.130  -0.242 0.860  0.302   -0.878  -1.343  15 C_DA9:DT-9_D C 9   ? D -9 ? 20 1 
# 
loop_
_ndb_struct_na_base_pair_step.model_number 
_ndb_struct_na_base_pair_step.i_label_asym_id_1 
_ndb_struct_na_base_pair_step.i_label_comp_id_1 
_ndb_struct_na_base_pair_step.i_label_seq_id_1 
_ndb_struct_na_base_pair_step.i_symmetry_1 
_ndb_struct_na_base_pair_step.j_label_asym_id_1 
_ndb_struct_na_base_pair_step.j_label_comp_id_1 
_ndb_struct_na_base_pair_step.j_label_seq_id_1 
_ndb_struct_na_base_pair_step.j_symmetry_1 
_ndb_struct_na_base_pair_step.i_label_asym_id_2 
_ndb_struct_na_base_pair_step.i_label_comp_id_2 
_ndb_struct_na_base_pair_step.i_label_seq_id_2 
_ndb_struct_na_base_pair_step.i_symmetry_2 
_ndb_struct_na_base_pair_step.j_label_asym_id_2 
_ndb_struct_na_base_pair_step.j_label_comp_id_2 
_ndb_struct_na_base_pair_step.j_label_seq_id_2 
_ndb_struct_na_base_pair_step.j_symmetry_2 
_ndb_struct_na_base_pair_step.shift 
_ndb_struct_na_base_pair_step.slide 
_ndb_struct_na_base_pair_step.rise 
_ndb_struct_na_base_pair_step.tilt 
_ndb_struct_na_base_pair_step.roll 
_ndb_struct_na_base_pair_step.twist 
_ndb_struct_na_base_pair_step.x_displacement 
_ndb_struct_na_base_pair_step.y_displacement 
_ndb_struct_na_base_pair_step.helical_rise 
_ndb_struct_na_base_pair_step.inclination 
_ndb_struct_na_base_pair_step.tip 
_ndb_struct_na_base_pair_step.helical_twist 
_ndb_struct_na_base_pair_step.step_number 
_ndb_struct_na_base_pair_step.step_name 
_ndb_struct_na_base_pair_step.i_auth_asym_id_1 
_ndb_struct_na_base_pair_step.i_auth_seq_id_1 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.j_auth_asym_id_1 
_ndb_struct_na_base_pair_step.j_auth_seq_id_1 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.i_auth_asym_id_2 
_ndb_struct_na_base_pair_step.i_auth_seq_id_2 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_2 
_ndb_struct_na_base_pair_step.j_auth_asym_id_2 
_ndb_struct_na_base_pair_step.j_auth_seq_id_2 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_2 
1 B G  10 1_555 B A  25 1_555 B C  11 1_555 B G  24 1_555 2.369  -0.584 3.362 -12.266 5.142  32.222 -1.674 -5.624 2.224 8.811  
21.017  34.791 1  BB_G-16C-15:G-2A-1_BB B -16 ? B -1 ? B -15 ? B -2 ? 
1 B C  11 1_555 B G  24 1_555 B U  12 1_555 B A  23 1_555 -0.349 -2.037 3.053 -9.936  16.387 31.681 -5.016 -0.538 1.843 27.137 
16.454  36.899 2  BB_C-15U-14:A-3G-2_BB B -15 ? B -2 ? B -14 ? B -3 ? 
1 B U  12 1_555 B A  23 1_555 B C  13 1_555 B G  22 1_555 0.026  -1.586 3.363 -0.901  13.362 37.005 -3.871 -0.141 2.654 20.256 
1.366   39.274 3  BB_U-14C-13:G-4A-3_BB B -14 ? B -3 ? B -13 ? B -4 ? 
1 B C  13 1_555 B G  22 1_555 B G  15 1_555 B C  21 1_555 -1.634 -1.771 5.862 17.156  8.029  34.787 -4.173 5.732  4.152 12.362 
-26.414 39.469 4  BB_C-13G-11:C-5G-4_BB B -13 ? B -4 ? B -11 ? B -5 ? 
1 B U  27 1_555 C DA 32 1_555 B C  29 1_555 C DG 31 1_555 -1.161 0.344  4.775 10.942  -5.941 34.891 1.665  3.899  4.127 -9.541 
-17.571 36.981 5  BB_U1C3:DG-2DA-1_CC   B 1   ? C -1 ? B 3   ? C -2 ? 
1 C DG 33 1_555 D DT 9  1_555 C DA 35 1_555 D DT 8  1_555 -0.181 -0.954 4.748 -0.091  -2.454 55.140 -0.819 0.188  4.784 -2.649 
0.098   55.191 6  CC_DG0DA2:DT-2DT-1_DD C 0   ? D -1 ? C 2   ? D -2 ? 
1 C DA 35 1_555 D DT 8  1_555 C DT 36 1_555 D DA 7  1_555 0.118  -1.149 3.148 3.618   -1.011 33.003 -1.846 0.381  3.176 -1.772 
-6.344  33.211 7  CC_DA2DT3:DA-3DT-2_DD C 2   ? D -2 ? C 3   ? D -3 ? 
1 C DT 36 1_555 D DA 7  1_555 C DT 37 1_555 D DA 6  1_555 0.899  -0.645 3.047 6.233   -1.273 37.721 -0.831 -0.622 3.169 -1.952 
-9.558  38.234 8  CC_DT3DT4:DA-4DA-3_DD C 3   ? D -3 ? C 4   ? D -4 ? 
1 C DT 37 1_555 D DA 6  1_555 C DG 38 1_555 D DC 5  1_555 -1.377 -0.041 3.332 -4.647  7.948  30.205 -1.627 1.625  3.382 14.825 
8.668   31.546 9  CC_DT4DG5:DC-5DA-4_DD C 4   ? D -4 ? C 5   ? D -5 ? 
1 C DG 38 1_555 D DC 5  1_555 C DG 39 1_555 D DC 4  1_555 -0.124 0.492  3.586 -0.817  0.005  38.970 0.737  0.078  3.588 0.007  
1.225   38.978 10 CC_DG5DG6:DC-6DC-5_DD C 5   ? D -5 ? C 6   ? D -6 ? 
1 C DG 39 1_555 D DC 4  1_555 C DC 41 1_555 D DG 2  1_555 0.220  0.972  7.386 -0.329  4.417  66.120 0.489  -0.231 7.429 4.043  
0.301   66.252 11 CC_DG6DC8:DG-8DC-6_DD C 6   ? D -6 ? C 8   ? D -8 ? 
1 C DC 41 1_555 D DG 2  1_555 C DA 42 1_555 D DT 1  1_555 -1.100 0.604  3.973 -2.446  1.554  35.238 0.713  1.368  4.059 2.561  
4.032   35.353 12 CC_DC8DA9:DT-9DG-8_DD C 8   ? D -8 ? C 9   ? D -9 ? 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           32188102 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    8WS9 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N     . PHE A 1 57  ? 141.916 124.189 129.104 1.00 84.93  ? 57  PHE A N     1 
ATOM 2    C CA    . PHE A 1 57  ? 140.729 124.774 128.492 1.00 84.93  ? 57  PHE A CA    1 
ATOM 3    C C     . PHE A 1 57  ? 139.818 123.701 127.910 1.00 84.93  ? 57  PHE A C     1 
ATOM 4    O O     . PHE A 1 57  ? 140.284 122.745 127.291 1.00 84.93  ? 57  PHE A O     1 
ATOM 5    C CB    . PHE A 1 57  ? 141.123 125.768 127.401 1.00 84.93  ? 57  PHE A CB    1 
ATOM 6    C CG    . PHE A 1 57  ? 139.957 126.310 126.628 1.00 84.93  ? 57  PHE A CG    1 
ATOM 7    C CD1   . PHE A 1 57  ? 139.141 127.285 127.176 1.00 84.93  ? 57  PHE A CD1   1 
ATOM 8    C CD2   . PHE A 1 57  ? 139.676 125.846 125.356 1.00 84.93  ? 57  PHE A CD2   1 
ATOM 9    C CE1   . PHE A 1 57  ? 138.067 127.786 126.468 1.00 84.93  ? 57  PHE A CE1   1 
ATOM 10   C CE2   . PHE A 1 57  ? 138.607 126.344 124.644 1.00 84.93  ? 57  PHE A CE2   1 
ATOM 11   C CZ    . PHE A 1 57  ? 137.800 127.315 125.201 1.00 84.93  ? 57  PHE A CZ    1 
ATOM 12   N N     . CYS A 1 58  ? 138.511 123.867 128.112 1.00 81.41  ? 58  CYS A N     1 
ATOM 13   C CA    . CYS A 1 58  ? 137.532 122.942 127.568 1.00 81.41  ? 58  CYS A CA    1 
ATOM 14   C C     . CYS A 1 58  ? 136.866 123.577 126.359 1.00 81.41  ? 58  CYS A C     1 
ATOM 15   O O     . CYS A 1 58  ? 136.114 124.550 126.520 1.00 81.41  ? 58  CYS A O     1 
ATOM 16   C CB    . CYS A 1 58  ? 136.488 122.577 128.621 1.00 81.41  ? 58  CYS A CB    1 
ATOM 17   S SG    . CYS A 1 58  ? 137.135 121.626 130.016 1.00 81.41  ? 58  CYS A SG    1 
ATOM 18   N N     . PRO A 1 59  ? 137.113 123.086 125.143 1.00 78.41  ? 59  PRO A N     1 
ATOM 19   C CA    . PRO A 1 59  ? 136.447 123.664 123.979 1.00 78.41  ? 59  PRO A CA    1 
ATOM 20   C C     . PRO A 1 59  ? 134.955 123.396 124.020 1.00 78.41  ? 59  PRO A C     1 
ATOM 21   O O     . PRO A 1 59  ? 134.503 122.401 124.612 1.00 78.41  ? 59  PRO A O     1 
ATOM 22   C CB    . PRO A 1 59  ? 137.119 122.946 122.793 1.00 78.41  ? 59  PRO A CB    1 
ATOM 23   C CG    . PRO A 1 59  ? 137.732 121.727 123.362 1.00 78.41  ? 59  PRO A CG    1 
ATOM 24   C CD    . PRO A 1 59  ? 138.081 122.039 124.780 1.00 78.41  ? 59  PRO A CD    1 
ATOM 25   N N     . PRO A 1 60  ? 134.150 124.261 123.420 1.00 74.38  ? 60  PRO A N     1 
ATOM 26   C CA    . PRO A 1 60  ? 132.696 124.096 123.457 1.00 74.38  ? 60  PRO A CA    1 
ATOM 27   C C     . PRO A 1 60  ? 132.202 123.183 122.339 1.00 74.38  ? 60  PRO A C     1 
ATOM 28   O O     . PRO A 1 60  ? 132.965 122.686 121.513 1.00 74.38  ? 60  PRO A O     1 
ATOM 29   C CB    . PRO A 1 60  ? 132.173 125.526 123.268 1.00 74.38  ? 60  PRO A CB    1 
ATOM 30   C CG    . PRO A 1 60  ? 133.394 126.423 123.340 1.00 74.38  ? 60  PRO A CG    1 
ATOM 31   C CD    . PRO A 1 60  ? 134.528 125.577 122.893 1.00 74.38  ? 60  PRO A CD    1 
ATOM 32   N N     . ALA A 1 61  ? 130.888 122.977 122.332 1.00 62.45  ? 61  ALA A N     1 
ATOM 33   C CA    . ALA A 1 61  ? 130.190 122.220 121.303 1.00 62.45  ? 61  ALA A CA    1 
ATOM 34   C C     . ALA A 1 61  ? 128.745 122.697 121.300 1.00 62.45  ? 61  ALA A C     1 
ATOM 35   O O     . ALA A 1 61  ? 128.303 123.382 122.227 1.00 62.45  ? 61  ALA A O     1 
ATOM 36   C CB    . ALA A 1 61  ? 130.295 120.713 121.550 1.00 62.45  ? 61  ALA A CB    1 
ATOM 37   N N     . LYS A 1 62  ? 128.037 122.432 120.205 1.00 53.09  ? 62  LYS A N     1 
ATOM 38   C CA    . LYS A 1 62  ? 126.671 122.933 120.063 1.00 53.09  ? 62  LYS A CA    1 
ATOM 39   C C     . LYS A 1 62  ? 125.815 121.921 119.329 1.00 53.09  ? 62  LYS A C     1 
ATOM 40   O O     . LYS A 1 62  ? 126.112 121.574 118.185 1.00 53.09  ? 62  LYS A O     1 
ATOM 41   C CB    . LYS A 1 62  ? 126.689 124.257 119.299 1.00 53.09  ? 62  LYS A CB    1 
ATOM 42   C CG    . LYS A 1 62  ? 125.407 125.058 119.399 1.00 53.09  ? 62  LYS A CG    1 
ATOM 43   C CD    . LYS A 1 62  ? 125.430 126.010 120.582 1.00 53.09  ? 62  LYS A CD    1 
ATOM 44   C CE    . LYS A 1 62  ? 126.456 127.115 120.390 1.00 53.09  ? 62  LYS A CE    1 
ATOM 45   N NZ    . LYS A 1 62  ? 125.884 128.454 120.700 1.00 53.09  ? 62  LYS A NZ    1 
ATOM 46   N N     . VAL A 1 63  ? 124.751 121.447 119.968 1.00 53.89  ? 63  VAL A N     1 
ATOM 47   C CA    . VAL A 1 63  ? 123.904 120.414 119.381 1.00 53.89  ? 63  VAL A CA    1 
ATOM 48   C C     . VAL A 1 63  ? 122.438 120.809 119.501 1.00 53.89  ? 63  VAL A C     1 
ATOM 49   O O     . VAL A 1 63  ? 122.030 121.504 120.432 1.00 53.89  ? 63  VAL A O     1 
ATOM 50   C CB    . VAL A 1 63  ? 124.130 119.032 120.029 1.00 53.89  ? 63  VAL A CB    1 
ATOM 51   C CG1   . VAL A 1 63  ? 125.578 118.618 119.890 1.00 53.89  ? 63  VAL A CG1   1 
ATOM 52   C CG2   . VAL A 1 63  ? 123.725 119.059 121.489 1.00 53.89  ? 63  VAL A CG2   1 
ATOM 53   N N     . ASN A 1 64  ? 121.636 120.305 118.564 1.00 62.33  ? 64  ASN A N     1 
ATOM 54   C CA    . ASN A 1 64  ? 120.254 120.729 118.372 1.00 62.33  ? 64  ASN A CA    1 
ATOM 55   C C     . ASN A 1 64  ? 119.314 119.714 119.000 1.00 62.33  ? 64  ASN A C     1 
ATOM 56   O O     . ASN A 1 64  ? 119.476 118.506 118.797 1.00 62.33  ? 64  ASN A O     1 
ATOM 57   C CB    . ASN A 1 64  ? 119.922 120.862 116.883 1.00 62.33  ? 64  ASN A CB    1 
ATOM 58   C CG    . ASN A 1 64  ? 120.762 121.910 116.187 1.00 62.33  ? 64  ASN A CG    1 
ATOM 59   O OD1   . ASN A 1 64  ? 120.985 122.993 116.716 1.00 62.33  ? 64  ASN A OD1   1 
ATOM 60   N ND2   . ASN A 1 64  ? 121.237 121.588 114.989 1.00 62.33  ? 64  ASN A ND2   1 
ATOM 61   N N     . ILE A 1 65  ? 118.328 120.201 119.759 1.00 62.80  ? 65  ILE A N     1 
ATOM 62   C CA    . ILE A 1 65  ? 117.345 119.293 120.338 1.00 62.80  ? 65  ILE A CA    1 
ATOM 63   C C     . ILE A 1 65  ? 116.289 118.941 119.296 1.00 62.80  ? 65  ILE A C     1 
ATOM 64   O O     . ILE A 1 65  ? 116.115 119.624 118.281 1.00 62.80  ? 65  ILE A O     1 
ATOM 65   C CB    . ILE A 1 65  ? 116.700 119.895 121.597 1.00 62.80  ? 65  ILE A CB    1 
ATOM 66   C CG1   . ILE A 1 65  ? 115.961 121.189 121.257 1.00 62.80  ? 65  ILE A CG1   1 
ATOM 67   C CG2   . ILE A 1 65  ? 117.754 120.147 122.664 1.00 62.80  ? 65  ILE A CG2   1 
ATOM 68   C CD1   . ILE A 1 65  ? 115.261 121.814 122.444 1.00 62.80  ? 65  ILE A CD1   1 
ATOM 69   N N     . LEU A 1 66  ? 115.573 117.851 119.555 1.00 67.13  ? 66  LEU A N     1 
ATOM 70   C CA    . LEU A 1 66  ? 114.529 117.385 118.652 1.00 67.13  ? 66  LEU A CA    1 
ATOM 71   C C     . LEU A 1 66  ? 113.142 117.474 119.261 1.00 67.13  ? 66  LEU A C     1 
ATOM 72   O O     . LEU A 1 66  ? 112.263 118.133 118.694 1.00 67.13  ? 66  LEU A O     1 
ATOM 73   C CB    . LEU A 1 66  ? 114.800 115.935 118.216 1.00 67.13  ? 66  LEU A CB    1 
ATOM 74   C CG    . LEU A 1 66  ? 116.021 115.644 117.345 1.00 67.13  ? 66  LEU A CG    1 
ATOM 75   C CD1   . LEU A 1 66  ? 115.956 114.217 116.822 1.00 67.13  ? 66  LEU A CD1   1 
ATOM 76   C CD2   . LEU A 1 66  ? 116.116 116.637 116.197 1.00 67.13  ? 66  LEU A CD2   1 
ATOM 77   N N     . ALA A 1 67  ? 112.916 116.832 120.403 1.00 71.01  ? 67  ALA A N     1 
ATOM 78   C CA    . ALA A 1 67  ? 111.579 116.730 120.967 1.00 71.01  ? 67  ALA A CA    1 
ATOM 79   C C     . ALA A 1 67  ? 111.638 116.875 122.478 1.00 71.01  ? 67  ALA A C     1 
ATOM 80   O O     . ALA A 1 67  ? 112.626 116.488 123.106 1.00 71.01  ? 67  ALA A O     1 
ATOM 81   C CB    . ALA A 1 67  ? 110.922 115.397 120.591 1.00 71.01  ? 67  ALA A CB    1 
ATOM 82   N N     . GLN A 1 68  ? 110.575 117.432 123.048 1.00 75.41  ? 68  GLN A N     1 
ATOM 83   C CA    . GLN A 1 68  ? 110.416 117.589 124.482 1.00 75.41  ? 68  GLN A CA    1 
ATOM 84   C C     . GLN A 1 68  ? 108.999 117.195 124.880 1.00 75.41  ? 68  GLN A C     1 
ATOM 85   O O     . GLN A 1 68  ? 108.062 117.281 124.081 1.00 75.41  ? 68  GLN A O     1 
ATOM 86   C CB    . GLN A 1 68  ? 110.705 119.028 124.913 1.00 75.41  ? 68  GLN A CB    1 
ATOM 87   C CG    . GLN A 1 68  ? 109.786 120.048 124.270 1.00 75.41  ? 68  GLN A CG    1 
ATOM 88   C CD    . GLN A 1 68  ? 110.118 121.464 124.676 1.00 75.41  ? 68  GLN A CD    1 
ATOM 89   O OE1   . GLN A 1 68  ? 111.031 121.696 125.468 1.00 75.41  ? 68  GLN A OE1   1 
ATOM 90   N NE2   . GLN A 1 68  ? 109.372 122.423 124.142 1.00 75.41  ? 68  GLN A NE2   1 
ATOM 91   N N     . SER A 1 69  ? 108.851 116.749 126.128 1.00 75.71  ? 69  SER A N     1 
ATOM 92   C CA    . SER A 1 69  ? 107.538 116.336 126.615 1.00 75.71  ? 69  SER A CA    1 
ATOM 93   C C     . SER A 1 69  ? 106.575 117.515 126.671 1.00 75.71  ? 69  SER A C     1 
ATOM 94   O O     . SER A 1 69  ? 105.442 117.434 126.184 1.00 75.71  ? 69  SER A O     1 
ATOM 95   C CB    . SER A 1 69  ? 107.670 115.680 127.990 1.00 75.71  ? 69  SER A CB    1 
ATOM 96   O OG    . SER A 1 69  ? 108.257 114.398 127.883 1.00 75.71  ? 69  SER A OG    1 
ATOM 97   N N     . ARG A 1 70  ? 107.028 118.585 127.328 1.00 75.19  ? 70  ARG A N     1 
ATOM 98   C CA    . ARG A 1 70  ? 106.200 119.773 127.503 1.00 75.19  ? 70  ARG A CA    1 
ATOM 99   C C     . ARG A 1 70  ? 107.023 121.037 127.116 1.00 75.19  ? 70  ARG A C     1 
ATOM 100  O O     . ARG A 1 70  ? 108.226 120.904 126.928 1.00 75.19  ? 70  ARG A O     1 
ATOM 101  C CB    . ARG A 1 70  ? 105.757 119.876 128.965 1.00 75.19  ? 70  ARG A CB    1 
ATOM 102  C CG    . ARG A 1 70  ? 104.621 118.944 129.351 1.00 75.19  ? 70  ARG A CG    1 
ATOM 103  C CD    . ARG A 1 70  ? 103.345 119.717 129.634 1.00 75.19  ? 70  ARG A CD    1 
ATOM 104  N NE    . ARG A 1 70  ? 102.604 120.008 128.411 1.00 75.19  ? 70  ARG A NE    1 
ATOM 105  C CZ    . ARG A 1 70  ? 101.771 121.033 128.268 1.00 75.19  ? 70  ARG A CZ    1 
ATOM 106  N NH1   . ARG A 1 70  ? 101.569 121.871 129.275 1.00 75.19  ? 70  ARG A NH1   1 
ATOM 107  N NH2   . ARG A 1 70  ? 101.139 121.221 127.118 1.00 75.19  ? 70  ARG A NH2   1 
ATOM 108  N N     . PRO A 1 71  ? 106.402 122.257 127.011 1.00 78.09  ? 71  PRO A N     1 
ATOM 109  C CA    . PRO A 1 71  ? 107.180 123.468 126.699 1.00 78.09  ? 71  PRO A CA    1 
ATOM 110  C C     . PRO A 1 71  ? 108.476 123.633 127.479 1.00 78.09  ? 71  PRO A C     1 
ATOM 111  O O     . PRO A 1 71  ? 108.642 123.092 128.578 1.00 78.09  ? 71  PRO A O     1 
ATOM 112  C CB    . PRO A 1 71  ? 106.194 124.595 127.023 1.00 78.09  ? 71  PRO A CB    1 
ATOM 113  C CG    . PRO A 1 71  ? 104.858 124.008 126.707 1.00 78.09  ? 71  PRO A CG    1 
ATOM 114  C CD    . PRO A 1 71  ? 104.953 122.507 126.882 1.00 78.09  ? 71  PRO A CD    1 
ATOM 115  N N     . LEU A 1 72  ? 109.458 124.230 126.816 1.00 75.65  ? 72  LEU A N     1 
ATOM 116  C CA    . LEU A 1 72  ? 110.790 124.348 127.404 1.00 75.65  ? 72  LEU A CA    1 
ATOM 117  C C     . LEU A 1 72  ? 110.843 124.781 128.849 1.00 75.65  ? 72  LEU A C     1 
ATOM 118  O O     . LEU A 1 72  ? 111.369 124.062 129.700 1.00 75.65  ? 72  LEU A O     1 
ATOM 119  C CB    . LEU A 1 72  ? 111.612 125.301 126.543 1.00 75.65  ? 72  LEU A CB    1 
ATOM 120  C CG    . LEU A 1 72  ? 111.313 125.316 125.042 1.00 75.65  ? 72  LEU A CG    1 
ATOM 121  C CD1   . LEU A 1 72  ? 110.921 126.711 124.582 1.00 75.65  ? 72  LEU A CD1   1 
ATOM 122  C CD2   . LEU A 1 72  ? 112.504 124.800 124.250 1.00 75.65  ? 72  LEU A CD2   1 
ATOM 123  N N     . SER A 1 73  ? 110.312 125.959 129.130 1.00 75.11  ? 73  SER A N     1 
ATOM 124  C CA    . SER A 1 73  ? 110.392 126.486 130.492 1.00 75.11  ? 73  SER A CA    1 
ATOM 125  C C     . SER A 1 73  ? 109.172 126.058 131.311 1.00 75.11  ? 73  SER A C     1 
ATOM 126  O O     . SER A 1 73  ? 108.430 126.872 131.860 1.00 75.11  ? 73  SER A O     1 
ATOM 127  C CB    . SER A 1 73  ? 110.539 128.003 130.464 1.00 75.11  ? 73  SER A CB    1 
ATOM 128  O OG    . SER A 1 73  ? 111.846 128.381 130.073 1.00 75.11  ? 73  SER A OG    1 
ATOM 129  N N     . GLU A 1 74  ? 108.975 124.742 131.384 1.00 75.93  ? 74  GLU A N     1 
ATOM 130  C CA    . GLU A 1 74  ? 107.910 124.182 132.205 1.00 75.93  ? 74  GLU A CA    1 
ATOM 131  C C     . GLU A 1 74  ? 108.358 122.974 133.015 1.00 75.93  ? 74  GLU A C     1 
ATOM 132  O O     . GLU A 1 74  ? 107.569 122.467 133.819 1.00 75.93  ? 74  GLU A O     1 
ATOM 133  C CB    . GLU A 1 74  ? 106.705 123.801 131.326 1.00 75.93  ? 74  GLU A CB    1 
ATOM 134  C CG    . GLU A 1 74  ? 105.405 123.541 132.085 1.00 75.93  ? 74  GLU A CG    1 
ATOM 135  C CD    . GLU A 1 74  ? 104.230 123.276 131.167 1.00 75.93  ? 74  GLU A CD    1 
ATOM 136  O OE1   . GLU A 1 74  ? 104.424 123.295 129.934 1.00 75.93  ? 74  GLU A OE1   1 
ATOM 137  O OE2   . GLU A 1 74  ? 103.114 123.049 131.679 1.00 75.93  ? 74  GLU A OE2   1 
ATOM 138  N N     . TRP A 1 75  ? 109.592 122.506 132.853 1.00 74.13  ? 75  TRP A N     1 
ATOM 139  C CA    . TRP A 1 75  ? 110.094 121.426 133.683 1.00 74.13  ? 75  TRP A CA    1 
ATOM 140  C C     . TRP A 1 75  ? 110.308 121.927 135.112 1.00 74.13  ? 75  TRP A C     1 
ATOM 141  O O     . TRP A 1 75  ? 110.581 123.112 135.326 1.00 74.13  ? 75  TRP A O     1 
ATOM 142  C CB    . TRP A 1 75  ? 111.393 120.877 133.100 1.00 74.13  ? 75  TRP A CB    1 
ATOM 143  C CG    . TRP A 1 75  ? 111.231 120.411 131.688 1.00 74.13  ? 75  TRP A CG    1 
ATOM 144  C CD1   . TRP A 1 75  ? 110.172 119.727 131.170 1.00 74.13  ? 75  TRP A CD1   1 
ATOM 145  C CD2   . TRP A 1 75  ? 112.152 120.602 130.613 1.00 74.13  ? 75  TRP A CD2   1 
ATOM 146  N NE1   . TRP A 1 75  ? 110.377 119.479 129.835 1.00 74.13  ? 75  TRP A NE1   1 
ATOM 147  C CE2   . TRP A 1 75  ? 111.587 120.007 129.470 1.00 74.13  ? 75  TRP A CE2   1 
ATOM 148  C CE3   . TRP A 1 75  ? 113.398 121.219 130.505 1.00 74.13  ? 75  TRP A CE3   1 
ATOM 149  C CZ2   . TRP A 1 75  ? 112.227 120.010 128.237 1.00 74.13  ? 75  TRP A CZ2   1 
ATOM 150  C CZ3   . TRP A 1 75  ? 114.031 121.222 129.281 1.00 74.13  ? 75  TRP A CZ3   1 
ATOM 151  C CH2   . TRP A 1 75  ? 113.446 120.623 128.164 1.00 74.13  ? 75  TRP A CH2   1 
ATOM 152  N N     . PRO A 1 76  ? 110.187 121.049 136.114 1.00 64.92  ? 76  PRO A N     1 
ATOM 153  C CA    . PRO A 1 76  ? 110.220 121.543 137.493 1.00 64.92  ? 76  PRO A CA    1 
ATOM 154  C C     . PRO A 1 76  ? 111.603 121.924 137.984 1.00 64.92  ? 76  PRO A C     1 
ATOM 155  O O     . PRO A 1 76  ? 111.704 122.709 138.935 1.00 64.92  ? 76  PRO A O     1 
ATOM 156  C CB    . PRO A 1 76  ? 109.612 120.370 138.278 1.00 64.92  ? 76  PRO A CB    1 
ATOM 157  C CG    . PRO A 1 76  ? 109.765 119.136 137.328 1.00 64.92  ? 76  PRO A CG    1 
ATOM 158  C CD    . PRO A 1 76  ? 110.540 119.622 136.133 1.00 64.92  ? 76  PRO A CD    1 
ATOM 159  N N     . ILE A 1 77  ? 112.672 121.418 137.368 1.00 65.72  ? 77  ILE A N     1 
ATOM 160  C CA    . ILE A 1 77  ? 114.002 121.911 137.704 1.00 65.72  ? 77  ILE A CA    1 
ATOM 161  C C     . ILE A 1 77  ? 114.114 123.385 137.345 1.00 65.72  ? 77  ILE A C     1 
ATOM 162  O O     . ILE A 1 77  ? 114.673 124.184 138.107 1.00 65.72  ? 77  ILE A O     1 
ATOM 163  C CB    . ILE A 1 77  ? 115.087 121.061 137.016 1.00 65.72  ? 77  ILE A CB    1 
ATOM 164  C CG1   . ILE A 1 77  ? 116.474 121.647 137.289 1.00 65.72  ? 77  ILE A CG1   1 
ATOM 165  C CG2   . ILE A 1 77  ? 114.818 120.927 135.520 1.00 65.72  ? 77  ILE A CG2   1 
ATOM 166  C CD1   . ILE A 1 77  ? 117.607 120.701 136.973 1.00 65.72  ? 77  ILE A CD1   1 
ATOM 167  N N     . ASN A 1 78  ? 113.564 123.775 136.194 1.00 69.78  ? 78  ASN A N     1 
ATOM 168  C CA    . ASN A 1 78  ? 113.513 125.193 135.858 1.00 69.78  ? 78  ASN A CA    1 
ATOM 169  C C     . ASN A 1 78  ? 112.566 125.947 136.782 1.00 69.78  ? 78  ASN A C     1 
ATOM 170  O O     . ASN A 1 78  ? 112.860 127.075 137.192 1.00 69.78  ? 78  ASN A O     1 
ATOM 171  C CB    . ASN A 1 78  ? 113.100 125.381 134.402 1.00 69.78  ? 78  ASN A CB    1 
ATOM 172  C CG    . ASN A 1 78  ? 113.375 126.779 133.904 1.00 69.78  ? 78  ASN A CG    1 
ATOM 173  O OD1   . ASN A 1 78  ? 114.236 127.477 134.435 1.00 69.78  ? 78  ASN A OD1   1 
ATOM 174  N ND2   . ASN A 1 78  ? 112.643 127.201 132.883 1.00 69.78  ? 78  ASN A ND2   1 
ATOM 175  N N     . LEU A 1 79  ? 111.427 125.341 137.124 1.00 69.36  ? 79  LEU A N     1 
ATOM 176  C CA    . LEU A 1 79  ? 110.480 125.976 138.033 1.00 69.36  ? 79  LEU A CA    1 
ATOM 177  C C     . LEU A 1 79  ? 111.047 126.164 139.432 1.00 69.36  ? 79  LEU A C     1 
ATOM 178  O O     . LEU A 1 79  ? 110.490 126.949 140.206 1.00 69.36  ? 79  LEU A O     1 
ATOM 179  C CB    . LEU A 1 79  ? 109.189 125.160 138.104 1.00 69.36  ? 79  LEU A CB    1 
ATOM 180  C CG    . LEU A 1 79  ? 108.361 125.080 136.820 1.00 69.36  ? 79  LEU A CG    1 
ATOM 181  C CD1   . LEU A 1 79  ? 107.118 124.229 137.033 1.00 69.36  ? 79  LEU A CD1   1 
ATOM 182  C CD2   . LEU A 1 79  ? 107.989 126.472 136.335 1.00 69.36  ? 79  LEU A CD2   1 
ATOM 183  N N     . VAL A 1 80  ? 112.122 125.463 139.774 1.00 68.86  ? 80  VAL A N     1 
ATOM 184  C CA    . VAL A 1 80  ? 112.831 125.668 141.033 1.00 68.86  ? 80  VAL A CA    1 
ATOM 185  C C     . VAL A 1 80  ? 113.963 126.672 140.876 1.00 68.86  ? 80  VAL A C     1 
ATOM 186  O O     . VAL A 1 80  ? 114.132 127.563 141.709 1.00 68.86  ? 80  VAL A O     1 
ATOM 187  C CB    . VAL A 1 80  ? 113.351 124.322 141.584 1.00 68.86  ? 80  VAL A CB    1 
ATOM 188  C CG1   . VAL A 1 80  ? 114.338 124.559 142.703 1.00 68.86  ? 80  VAL A CG1   1 
ATOM 189  C CG2   . VAL A 1 80  ? 112.201 123.479 142.082 1.00 68.86  ? 80  VAL A CG2   1 
ATOM 190  N N     . SER A 1 81  ? 114.746 126.553 139.802 1.00 65.60  ? 81  SER A N     1 
ATOM 191  C CA    . SER A 1 81  ? 115.891 127.440 139.621 1.00 65.60  ? 81  SER A CA    1 
ATOM 192  C C     . SER A 1 81  ? 115.459 128.856 139.269 1.00 65.60  ? 81  SER A C     1 
ATOM 193  O O     . SER A 1 81  ? 116.260 129.793 139.358 1.00 65.60  ? 81  SER A O     1 
ATOM 194  C CB    . SER A 1 81  ? 116.820 126.893 138.540 1.00 65.60  ? 81  SER A CB    1 
ATOM 195  O OG    . SER A 1 81  ? 117.831 127.837 138.231 1.00 65.60  ? 81  SER A OG    1 
ATOM 196  N N     . LYS A 1 82  ? 114.207 129.033 138.842 1.00 69.98  ? 82  LYS A N     1 
ATOM 197  C CA    . LYS A 1 82  ? 113.765 130.355 138.411 1.00 69.98  ? 82  LYS A CA    1 
ATOM 198  C C     . LYS A 1 82  ? 113.603 131.305 139.590 1.00 69.98  ? 82  LYS A C     1 
ATOM 199  O O     . LYS A 1 82  ? 114.061 132.453 139.540 1.00 69.98  ? 82  LYS A O     1 
ATOM 200  C CB    . LYS A 1 82  ? 112.454 130.238 137.634 1.00 69.98  ? 82  LYS A CB    1 
ATOM 201  C CG    . LYS A 1 82  ? 111.790 131.571 137.327 1.00 69.98  ? 82  LYS A CG    1 
ATOM 202  C CD    . LYS A 1 82  ? 110.536 131.383 136.490 1.00 69.98  ? 82  LYS A CD    1 
ATOM 203  C CE    . LYS A 1 82  ? 109.863 132.714 136.201 1.00 69.98  ? 82  LYS A CE    1 
ATOM 204  N NZ    . LYS A 1 82  ? 110.797 133.678 135.557 1.00 69.98  ? 82  LYS A NZ    1 
ATOM 205  N N     . GLY A 1 83  ? 112.959 130.846 140.663 1.00 67.19  ? 83  GLY A N     1 
ATOM 206  C CA    . GLY A 1 83  ? 112.635 131.750 141.754 1.00 67.19  ? 83  GLY A CA    1 
ATOM 207  C C     . GLY A 1 83  ? 113.815 132.033 142.663 1.00 67.19  ? 83  GLY A C     1 
ATOM 208  O O     . GLY A 1 83  ? 113.764 132.942 143.494 1.00 67.19  ? 83  GLY A O     1 
ATOM 209  N N     . VAL A 1 84  ? 114.864 131.222 142.546 1.00 67.37  ? 84  VAL A N     1 
ATOM 210  C CA    . VAL A 1 84  ? 116.021 131.376 143.426 1.00 67.37  ? 84  VAL A CA    1 
ATOM 211  C C     . VAL A 1 84  ? 116.655 132.752 143.274 1.00 67.37  ? 84  VAL A C     1 
ATOM 212  O O     . VAL A 1 84  ? 116.916 133.433 144.265 1.00 67.37  ? 84  VAL A O     1 
ATOM 213  C CB    . VAL A 1 84  ? 117.082 130.281 143.196 1.00 67.37  ? 84  VAL A CB    1 
ATOM 214  C CG1   . VAL A 1 84  ? 118.234 130.454 144.170 1.00 67.37  ? 84  VAL A CG1   1 
ATOM 215  C CG2   . VAL A 1 84  ? 116.468 128.906 143.384 1.00 67.37  ? 84  VAL A CG2   1 
ATOM 216  N N     . GLN A 1 85  ? 116.900 133.164 142.035 1.00 68.78  ? 85  GLN A N     1 
ATOM 217  C CA    . GLN A 1 85  ? 117.547 134.456 141.823 1.00 68.78  ? 85  GLN A CA    1 
ATOM 218  C C     . GLN A 1 85  ? 116.664 135.599 142.305 1.00 68.78  ? 85  GLN A C     1 
ATOM 219  O O     . GLN A 1 85  ? 117.164 136.608 142.816 1.00 68.78  ? 85  GLN A O     1 
ATOM 220  C CB    . GLN A 1 85  ? 117.914 134.637 140.350 1.00 68.78  ? 85  GLN A CB    1 
ATOM 221  C CG    . GLN A 1 85  ? 118.456 136.026 139.961 1.00 68.78  ? 85  GLN A CG    1 
ATOM 222  C CD    . GLN A 1 85  ? 119.561 136.575 140.863 1.00 68.78  ? 85  GLN A CD    1 
ATOM 223  O OE1   . GLN A 1 85  ? 120.134 135.867 141.689 1.00 68.78  ? 85  GLN A OE1   1 
ATOM 224  N NE2   . GLN A 1 85  ? 119.865 137.856 140.694 1.00 68.78  ? 85  GLN A NE2   1 
ATOM 225  N N     . GLU A 1 86  ? 115.345 135.463 142.147 1.00 70.69  ? 86  GLU A N     1 
ATOM 226  C CA    . GLU A 1 86  ? 114.431 136.465 142.685 1.00 70.69  ? 86  GLU A CA    1 
ATOM 227  C C     . GLU A 1 86  ? 114.510 136.519 144.205 1.00 70.69  ? 86  GLU A C     1 
ATOM 228  O O     . GLU A 1 86  ? 114.490 137.603 144.798 1.00 70.69  ? 86  GLU A O     1 
ATOM 229  C CB    . GLU A 1 86  ? 113.003 136.170 142.231 1.00 70.69  ? 86  GLU A CB    1 
ATOM 230  C CG    . GLU A 1 86  ? 112.864 135.941 140.736 1.00 70.69  ? 86  GLU A CG    1 
ATOM 231  C CD    . GLU A 1 86  ? 111.631 135.134 140.381 1.00 70.69  ? 86  GLU A CD    1 
ATOM 232  O OE1   . GLU A 1 86  ? 110.921 134.691 141.309 1.00 70.69  ? 86  GLU A OE1   1 
ATOM 233  O OE2   . GLU A 1 86  ? 111.370 134.944 139.175 1.00 70.69  ? 86  GLU A OE2   1 
ATOM 234  N N     . TYR A 1 87  ? 114.594 135.355 144.852 1.00 70.27  ? 87  TYR A N     1 
ATOM 235  C CA    . TYR A 1 87  ? 114.698 135.320 146.307 1.00 70.27  ? 87  TYR A CA    1 
ATOM 236  C C     . TYR A 1 87  ? 116.009 135.933 146.778 1.00 70.27  ? 87  TYR A C     1 
ATOM 237  O O     . TYR A 1 87  ? 116.039 136.667 147.773 1.00 70.27  ? 87  TYR A O     1 
ATOM 238  C CB    . TYR A 1 87  ? 114.573 133.884 146.809 1.00 70.27  ? 87  TYR A CB    1 
ATOM 239  C CG    . TYR A 1 87  ? 114.288 133.766 148.289 1.00 70.27  ? 87  TYR A CG    1 
ATOM 240  C CD1   . TYR A 1 87  ? 113.106 134.257 148.828 1.00 70.27  ? 87  TYR A CD1   1 
ATOM 241  C CD2   . TYR A 1 87  ? 115.198 133.163 149.146 1.00 70.27  ? 87  TYR A CD2   1 
ATOM 242  C CE1   . TYR A 1 87  ? 112.837 134.150 150.180 1.00 70.27  ? 87  TYR A CE1   1 
ATOM 243  C CE2   . TYR A 1 87  ? 114.939 133.052 150.501 1.00 70.27  ? 87  TYR A CE2   1 
ATOM 244  C CZ    . TYR A 1 87  ? 113.757 133.548 151.012 1.00 70.27  ? 87  TYR A CZ    1 
ATOM 245  O OH    . TYR A 1 87  ? 113.495 133.441 152.358 1.00 70.27  ? 87  TYR A OH    1 
ATOM 246  N N     . VAL A 1 88  ? 117.098 135.632 146.075 1.00 65.76  ? 88  VAL A N     1 
ATOM 247  C CA    . VAL A 1 88  ? 118.413 136.140 146.469 1.00 65.76  ? 88  VAL A CA    1 
ATOM 248  C C     . VAL A 1 88  ? 118.850 137.304 145.586 1.00 65.76  ? 88  VAL A C     1 
ATOM 249  O O     . VAL A 1 88  ? 118.181 138.334 145.522 1.00 65.76  ? 88  VAL A O     1 
ATOM 250  C CB    . VAL A 1 88  ? 119.482 135.033 146.402 1.00 65.76  ? 88  VAL A CB    1 
ATOM 251  C CG1   . VAL A 1 88  ? 120.801 135.532 146.968 1.00 65.76  ? 88  VAL A CG1   1 
ATOM 252  C CG2   . VAL A 1 88  ? 119.016 133.800 147.158 1.00 65.76  ? 88  VAL A CG2   1 
ATOM 253  N N     . ALA A 1 98  ? 117.114 134.350 153.786 1.00 77.36  ? 98  ALA A N     1 
ATOM 254  C CA    . ALA A 1 98  ? 117.717 133.272 153.012 1.00 77.36  ? 98  ALA A CA    1 
ATOM 255  C C     . ALA A 1 98  ? 118.448 132.294 153.913 1.00 77.36  ? 98  ALA A C     1 
ATOM 256  O O     . ALA A 1 98  ? 118.848 131.228 153.443 1.00 77.36  ? 98  ALA A O     1 
ATOM 257  C CB    . ALA A 1 98  ? 118.663 133.836 151.963 1.00 77.36  ? 98  ALA A CB    1 
ATOM 258  N N     . ASN A 1 99  ? 118.640 132.654 155.185 1.00 67.98  ? 99  ASN A N     1 
ATOM 259  C CA    . ASN A 1 99  ? 119.341 131.794 156.161 1.00 67.98  ? 99  ASN A CA    1 
ATOM 260  C C     . ASN A 1 99  ? 120.851 131.695 155.963 1.00 67.98  ? 99  ASN A C     1 
ATOM 261  O O     . ASN A 1 99  ? 121.615 131.974 156.886 1.00 67.98  ? 99  ASN A O     1 
ATOM 262  C CB    . ASN A 1 99  ? 118.701 130.404 156.317 1.00 67.98  ? 99  ASN A CB    1 
ATOM 263  C CG    . ASN A 1 99  ? 117.468 130.427 157.196 1.00 67.98  ? 99  ASN A CG    1 
ATOM 264  O OD1   . ASN A 1 99  ? 116.930 131.491 157.502 1.00 67.98  ? 99  ASN A OD1   1 
ATOM 265  N ND2   . ASN A 1 99  ? 117.012 129.249 157.606 1.00 67.98  ? 99  ASN A ND2   1 
ATOM 266  N N     . GLY A 1 100 ? 121.287 131.296 154.774 1.00 71.13  ? 100 GLY A N     1 
ATOM 267  C CA    . GLY A 1 100 ? 122.707 131.126 154.527 1.00 71.13  ? 100 GLY A CA    1 
ATOM 268  C C     . GLY A 1 100 ? 123.195 129.766 154.974 1.00 71.13  ? 100 GLY A C     1 
ATOM 269  O O     . GLY A 1 100 ? 124.397 129.506 154.964 1.00 71.13  ? 100 GLY A O     1 
ATOM 270  N N     . ASP A 1 101 ? 122.274 128.891 155.369 1.00 75.27  ? 101 ASP A N     1 
ATOM 271  C CA    . ASP A 1 101 ? 122.652 127.537 155.755 1.00 75.27  ? 101 ASP A CA    1 
ATOM 272  C C     . ASP A 1 101 ? 122.742 126.696 154.496 1.00 75.27  ? 101 ASP A C     1 
ATOM 273  O O     . ASP A 1 101 ? 121.877 125.860 154.236 1.00 75.27  ? 101 ASP A O     1 
ATOM 274  C CB    . ASP A 1 101 ? 121.626 126.943 156.719 1.00 75.27  ? 101 ASP A CB    1 
ATOM 275  C CG    . ASP A 1 101 ? 122.132 125.692 157.415 1.00 75.27  ? 101 ASP A CG    1 
ATOM 276  O OD1   . ASP A 1 101 ? 123.345 125.406 157.332 1.00 75.27  ? 101 ASP A OD1   1 
ATOM 277  O OD2   . ASP A 1 101 ? 121.315 124.997 158.050 1.00 75.27  ? 101 ASP A OD2   1 
ATOM 278  N N     . PHE A 1 102 ? 123.790 126.911 153.712 1.00 74.97  ? 102 PHE A N     1 
ATOM 279  C CA    . PHE A 1 102 ? 123.941 126.187 152.460 1.00 74.97  ? 102 PHE A CA    1 
ATOM 280  C C     . PHE A 1 102 ? 125.036 125.141 152.592 1.00 74.97  ? 102 PHE A C     1 
ATOM 281  O O     . PHE A 1 102 ? 126.151 125.457 153.007 1.00 74.97  ? 102 PHE A O     1 
ATOM 282  C CB    . PHE A 1 102 ? 124.261 127.171 151.333 1.00 74.97  ? 102 PHE A CB    1 
ATOM 283  C CG    . PHE A 1 102 ? 124.556 126.514 150.019 1.00 74.97  ? 102 PHE A CG    1 
ATOM 284  C CD1   . PHE A 1 102 ? 123.558 125.866 149.315 1.00 74.97  ? 102 PHE A CD1   1 
ATOM 285  C CD2   . PHE A 1 102 ? 125.831 126.558 149.480 1.00 74.97  ? 102 PHE A CD2   1 
ATOM 286  C CE1   . PHE A 1 102 ? 123.829 125.264 148.105 1.00 74.97  ? 102 PHE A CE1   1 
ATOM 287  C CE2   . PHE A 1 102 ? 126.108 125.957 148.270 1.00 74.97  ? 102 PHE A CE2   1 
ATOM 288  C CZ    . PHE A 1 102 ? 125.104 125.311 147.580 1.00 74.97  ? 102 PHE A CZ    1 
ATOM 289  N N     . GLY A 1 103 ? 124.723 123.898 152.244 1.00 76.64  ? 103 GLY A N     1 
ATOM 290  C CA    . GLY A 1 103 ? 125.696 122.830 152.356 1.00 76.64  ? 103 GLY A CA    1 
ATOM 291  C C     . GLY A 1 103 ? 125.358 121.749 151.361 1.00 76.64  ? 103 GLY A C     1 
ATOM 292  O O     . GLY A 1 103 ? 124.209 121.636 150.941 1.00 76.64  ? 103 GLY A O     1 
ATOM 293  N N     . THR A 1 104 ? 126.344 120.949 150.978 1.00 72.09  ? 104 THR A N     1 
ATOM 294  C CA    . THR A 1 104 ? 126.076 119.836 150.079 1.00 72.09  ? 104 THR A CA    1 
ATOM 295  C C     . THR A 1 104 ? 125.129 118.862 150.756 1.00 72.09  ? 104 THR A C     1 
ATOM 296  O O     . THR A 1 104 ? 124.225 118.327 150.121 1.00 72.09  ? 104 THR A O     1 
ATOM 297  C CB    . THR A 1 104 ? 127.367 119.106 149.669 1.00 72.09  ? 104 THR A CB    1 
ATOM 298  O OG1   . THR A 1 104 ? 128.013 118.575 150.832 1.00 72.09  ? 104 THR A OG1   1 
ATOM 299  C CG2   . THR A 1 104 ? 128.312 120.064 148.963 1.00 72.09  ? 104 THR A CG2   1 
ATOM 300  N N     . SER A 1 105 ? 125.327 118.638 152.050 1.00 76.01  ? 105 SER A N     1 
ATOM 301  C CA    . SER A 1 105 ? 124.489 117.699 152.788 1.00 76.01  ? 105 SER A CA    1 
ATOM 302  C C     . SER A 1 105 ? 122.992 117.930 152.642 1.00 76.01  ? 105 SER A C     1 
ATOM 303  O O     . SER A 1 105 ? 122.521 119.059 152.774 1.00 76.01  ? 105 SER A O     1 
ATOM 304  C CB    . SER A 1 105 ? 124.871 117.696 154.270 1.00 76.01  ? 105 SER A CB    1 
ATOM 305  O OG    . SER A 1 105 ? 124.730 118.987 154.834 1.00 76.01  ? 105 SER A OG    1 
ATOM 306  N N     . ARG A 1 106 ? 122.243 116.865 152.370 1.00 75.06  ? 106 ARG A N     1 
ATOM 307  C CA    . ARG A 1 106 ? 120.794 116.985 152.205 1.00 75.06  ? 106 ARG A CA    1 
ATOM 308  C C     . ARG A 1 106 ? 120.141 117.702 153.375 1.00 75.06  ? 106 ARG A C     1 
ATOM 309  O O     . ARG A 1 106 ? 119.177 118.441 153.192 1.00 75.06  ? 106 ARG A O     1 
ATOM 310  C CB    . ARG A 1 106 ? 120.147 115.609 152.039 1.00 75.06  ? 106 ARG A CB    1 
ATOM 311  C CG    . ARG A 1 106 ? 119.621 115.332 150.641 1.00 75.06  ? 106 ARG A CG    1 
ATOM 312  C CD    . ARG A 1 106 ? 118.872 116.528 150.072 1.00 75.06  ? 106 ARG A CD    1 
ATOM 313  N NE    . ARG A 1 106 ? 117.645 116.822 150.806 1.00 75.06  ? 106 ARG A NE    1 
ATOM 314  C CZ    . ARG A 1 106 ? 116.838 117.840 150.528 1.00 75.06  ? 106 ARG A CZ    1 
ATOM 315  N NH1   . ARG A 1 106 ? 117.127 118.664 149.531 1.00 75.06  ? 106 ARG A NH1   1 
ATOM 316  N NH2   . ARG A 1 106 ? 115.741 118.035 151.247 1.00 75.06  ? 106 ARG A NH2   1 
ATOM 317  N N     . LYS A 1 107 ? 120.655 117.477 154.578 1.00 72.61  ? 107 LYS A N     1 
ATOM 318  C CA    . LYS A 1 107 ? 120.073 118.099 155.761 1.00 72.61  ? 107 LYS A CA    1 
ATOM 319  C C     . LYS A 1 107 ? 120.178 119.614 155.707 1.00 72.61  ? 107 LYS A C     1 
ATOM 320  O O     . LYS A 1 107 ? 119.235 120.318 156.063 1.00 72.61  ? 107 LYS A O     1 
ATOM 321  C CB    . LYS A 1 107 ? 120.743 117.569 157.028 1.00 72.61  ? 107 LYS A CB    1 
ATOM 322  C CG    . LYS A 1 107 ? 120.580 116.072 157.229 1.00 72.61  ? 107 LYS A CG    1 
ATOM 323  C CD    . LYS A 1 107 ? 119.115 115.679 157.347 1.00 72.61  ? 107 LYS A CD    1 
ATOM 324  C CE    . LYS A 1 107 ? 118.484 116.242 158.612 1.00 72.61  ? 107 LYS A CE    1 
ATOM 325  N NZ    . LYS A 1 107 ? 119.143 115.725 159.843 1.00 72.61  ? 107 LYS A NZ    1 
ATOM 326  N N     . SER A 1 108 ? 121.319 120.119 155.257 1.00 74.20  ? 108 SER A N     1 
ATOM 327  C CA    . SER A 1 108 ? 121.492 121.559 155.142 1.00 74.20  ? 108 SER A CA    1 
ATOM 328  C C     . SER A 1 108 ? 120.641 122.094 154.000 1.00 74.20  ? 108 SER A C     1 
ATOM 329  O O     . SER A 1 108 ? 120.082 123.186 154.100 1.00 74.20  ? 108 SER A O     1 
ATOM 330  C CB    . SER A 1 108 ? 122.961 121.915 154.923 1.00 74.20  ? 108 SER A CB    1 
ATOM 331  O OG    . SER A 1 108 ? 123.143 123.319 154.892 1.00 74.20  ? 108 SER A OG    1 
ATOM 332  N N     . LEU A 1 109 ? 120.537 121.326 152.917 1.00 71.61  ? 109 LEU A N     1 
ATOM 333  C CA    . LEU A 1 109 ? 119.727 121.758 151.787 1.00 71.61  ? 109 LEU A CA    1 
ATOM 334  C C     . LEU A 1 109 ? 118.269 121.861 152.188 1.00 71.61  ? 109 LEU A C     1 
ATOM 335  O O     . LEU A 1 109 ? 117.588 122.788 151.785 1.00 71.61  ? 109 LEU A O     1 
ATOM 336  C CB    . LEU A 1 109 ? 119.872 120.798 150.604 1.00 71.61  ? 109 LEU A CB    1 
ATOM 337  C CG    . LEU A 1 109 ? 121.132 120.942 149.749 1.00 71.61  ? 109 LEU A CG    1 
ATOM 338  C CD1   . LEU A 1 109 ? 121.233 119.819 148.729 1.00 71.61  ? 109 LEU A CD1   1 
ATOM 339  C CD2   . LEU A 1 109 ? 121.168 122.300 149.068 1.00 71.61  ? 109 LEU A CD2   1 
ATOM 340  N N     . ASP A 1 110 ? 117.790 120.913 152.985 1.00 69.66  ? 110 ASP A N     1 
ATOM 341  C CA    . ASP A 1 110 ? 116.407 120.947 153.443 1.00 69.66  ? 110 ASP A CA    1 
ATOM 342  C C     . ASP A 1 110 ? 116.155 122.249 154.182 1.00 69.66  ? 110 ASP A C     1 
ATOM 343  O O     . ASP A 1 110 ? 115.153 122.925 153.943 1.00 69.66  ? 110 ASP A O     1 
ATOM 344  C CB    . ASP A 1 110 ? 116.126 119.763 154.365 1.00 69.66  ? 110 ASP A CB    1 
ATOM 345  C CG    . ASP A 1 110 ? 114.646 119.535 154.585 1.00 69.66  ? 110 ASP A CG    1 
ATOM 346  O OD1   . ASP A 1 110 ? 113.843 119.947 153.721 1.00 69.66  ? 110 ASP A OD1   1 
ATOM 347  O OD2   . ASP A 1 110 ? 114.286 118.933 155.618 1.00 69.66  ? 110 ASP A OD2   1 
ATOM 348  N N     . ARG A 1 111 ? 117.068 122.605 155.079 1.00 69.77  ? 111 ARG A N     1 
ATOM 349  C CA    . ARG A 1 111 ? 116.914 123.831 155.853 1.00 69.77  ? 111 ARG A CA    1 
ATOM 350  C C     . ARG A 1 111 ? 116.930 125.094 155.003 1.00 69.77  ? 111 ARG A C     1 
ATOM 351  O O     . ARG A 1 111 ? 116.173 126.027 155.258 1.00 69.77  ? 111 ARG A O     1 
ATOM 352  C CB    . ARG A 1 111 ? 117.980 123.912 156.944 1.00 69.77  ? 111 ARG A CB    1 
ATOM 353  C CG    . ARG A 1 111 ? 117.868 122.806 157.977 1.00 69.77  ? 111 ARG A CG    1 
ATOM 354  C CD    . ARG A 1 111 ? 118.729 123.098 159.193 1.00 69.77  ? 111 ARG A CD    1 
ATOM 355  N NE    . ARG A 1 111 ? 118.430 124.409 159.763 1.00 69.77  ? 111 ARG A NE    1 
ATOM 356  C CZ    . ARG A 1 111 ? 117.519 124.626 160.707 1.00 69.77  ? 111 ARG A CZ    1 
ATOM 357  N NH1   . ARG A 1 111 ? 116.811 123.617 161.197 1.00 69.77  ? 111 ARG A NH1   1 
ATOM 358  N NH2   . ARG A 1 111 ? 117.316 125.854 161.162 1.00 69.77  ? 111 ARG A NH2   1 
ATOM 359  N N     . TRP A 1 112 ? 117.798 125.140 154.002 1.00 64.77  ? 112 TRP A N     1 
ATOM 360  C CA    . TRP A 1 112 ? 117.902 126.346 153.198 1.00 64.77  ? 112 TRP A CA    1 
ATOM 361  C C     . TRP A 1 112 ? 116.672 126.564 152.339 1.00 64.77  ? 112 TRP A C     1 
ATOM 362  O O     . TRP A 1 112 ? 116.244 127.698 152.155 1.00 64.77  ? 112 TRP A O     1 
ATOM 363  C CB    . TRP A 1 112 ? 119.146 126.317 152.299 1.00 64.77  ? 112 TRP A CB    1 
ATOM 364  C CG    . TRP A 1 112 ? 119.580 127.691 151.857 1.00 64.77  ? 112 TRP A CG    1 
ATOM 365  C CD1   . TRP A 1 112 ? 120.537 128.469 152.436 1.00 64.77  ? 112 TRP A CD1   1 
ATOM 366  C CD2   . TRP A 1 112 ? 119.058 128.455 150.757 1.00 64.77  ? 112 TRP A CD2   1 
ATOM 367  N NE1   . TRP A 1 112 ? 120.651 129.662 151.766 1.00 64.77  ? 112 TRP A NE1   1 
ATOM 368  C CE2   . TRP A 1 112 ? 119.752 129.678 150.733 1.00 64.77  ? 112 TRP A CE2   1 
ATOM 369  C CE3   . TRP A 1 112 ? 118.077 128.220 149.789 1.00 64.77  ? 112 TRP A CE3   1 
ATOM 370  C CZ2   . TRP A 1 112 ? 119.491 130.662 149.786 1.00 64.77  ? 112 TRP A CZ2   1 
ATOM 371  C CZ3   . TRP A 1 112 ? 117.817 129.201 148.856 1.00 64.77  ? 112 TRP A CZ3   1 
ATOM 372  C CH2   . TRP A 1 112 ? 118.526 130.403 148.855 1.00 64.77  ? 112 TRP A CH2   1 
ATOM 373  N N     . PHE A 1 113 ? 116.078 125.496 151.823 1.00 61.82  ? 113 PHE A N     1 
ATOM 374  C CA    . PHE A 1 113 ? 114.978 125.686 150.888 1.00 61.82  ? 113 PHE A CA    1 
ATOM 375  C C     . PHE A 1 113 ? 113.591 125.617 151.499 1.00 61.82  ? 113 PHE A C     1 
ATOM 376  O O     . PHE A 1 113 ? 112.925 126.643 151.637 1.00 61.82  ? 113 PHE A O     1 
ATOM 377  C CB    . PHE A 1 113 ? 115.087 124.649 149.772 1.00 61.82  ? 113 PHE A CB    1 
ATOM 378  C CG    . PHE A 1 113 ? 114.931 125.223 148.399 1.00 61.82  ? 113 PHE A CG    1 
ATOM 379  C CD1   . PHE A 1 113 ? 113.787 124.991 147.663 1.00 61.82  ? 113 PHE A CD1   1 
ATOM 380  C CD2   . PHE A 1 113 ? 115.930 126.000 147.847 1.00 61.82  ? 113 PHE A CD2   1 
ATOM 381  C CE1   . PHE A 1 113 ? 113.646 125.518 146.396 1.00 61.82  ? 113 PHE A CE1   1 
ATOM 382  C CE2   . PHE A 1 113 ? 115.793 126.535 146.583 1.00 61.82  ? 113 PHE A CE2   1 
ATOM 383  C CZ    . PHE A 1 113 ? 114.649 126.293 145.856 1.00 61.82  ? 113 PHE A CZ    1 
ATOM 384  N N     . ALA A 1 114 ? 113.149 124.423 151.876 1.00 63.63  ? 114 ALA A N     1 
ATOM 385  C CA    . ALA A 1 114 ? 111.789 124.291 152.384 1.00 63.63  ? 114 ALA A CA    1 
ATOM 386  C C     . ALA A 1 114 ? 111.554 125.039 153.690 1.00 63.63  ? 114 ALA A C     1 
ATOM 387  O O     . ALA A 1 114 ? 110.554 125.744 153.834 1.00 63.63  ? 114 ALA A O     1 
ATOM 388  C CB    . ALA A 1 114 ? 111.433 122.820 152.549 1.00 63.63  ? 114 ALA A CB    1 
ATOM 389  N N     . ARG A 1 115 ? 112.480 124.903 154.634 1.00 30.00  ? 115 ARG A N     1 
ATOM 390  C CA    . ARG A 1 115 ? 112.334 125.564 155.932 1.00 30.00  ? 115 ARG A CA    1 
ATOM 391  C C     . ARG A 1 115 ? 112.379 127.085 155.833 1.00 30.00  ? 115 ARG A C     1 
ATOM 392  O O     . ARG A 1 115 ? 111.513 127.765 156.385 1.00 30.00  ? 115 ARG A O     1 
ATOM 393  C CB    . ARG A 1 115 ? 113.399 125.076 156.919 1.00 30.00  ? 115 ARG A CB    1 
ATOM 394  C CG    . ARG A 1 115 ? 113.017 123.846 157.729 1.00 30.00  ? 115 ARG A CG    1 
ATOM 395  C CD    . ARG A 1 115 ? 113.554 122.558 157.122 1.00 30.00  ? 115 ARG A CD    1 
ATOM 396  N NE    . ARG A 1 115 ? 112.686 122.021 156.079 1.00 30.00  ? 115 ARG A NE    1 
ATOM 397  C CZ    . ARG A 1 115 ? 111.735 121.117 156.292 1.00 30.00  ? 115 ARG A CZ    1 
ATOM 398  N NH1   . ARG A 1 115 ? 111.532 120.640 157.513 1.00 30.00  ? 115 ARG A NH1   1 
ATOM 399  N NH2   . ARG A 1 115 ? 110.992 120.681 155.285 1.00 30.00  ? 115 ARG A NH2   1 
ATOM 400  N N     . THR A 1 116 ? 113.382 127.623 155.143 1.00 65.06  ? 116 THR A N     1 
ATOM 401  C CA    . THR A 1 116 ? 113.526 129.073 155.042 1.00 65.06  ? 116 THR A CA    1 
ATOM 402  C C     . THR A 1 116 ? 112.277 129.676 154.408 1.00 65.06  ? 116 THR A C     1 
ATOM 403  O O     . THR A 1 116 ? 111.833 130.757 154.799 1.00 65.06  ? 116 THR A O     1 
ATOM 404  C CB    . THR A 1 116 ? 114.788 129.480 154.258 1.00 65.06  ? 116 THR A CB    1 
ATOM 405  O OG1   . THR A 1 116 ? 115.939 128.878 154.861 1.00 65.06  ? 116 THR A OG1   1 
ATOM 406  C CG2   . THR A 1 116 ? 114.974 130.985 154.257 1.00 65.06  ? 116 THR A CG2   1 
ATOM 407  N N     . GLY A 1 117 ? 111.684 128.966 153.454 1.00 65.06  ? 117 GLY A N     1 
ATOM 408  C CA    . GLY A 1 117 ? 110.459 129.456 152.849 1.00 65.06  ? 117 GLY A CA    1 
ATOM 409  C C     . GLY A 1 117 ? 110.275 129.227 151.364 1.00 65.06  ? 117 GLY A C     1 
ATOM 410  O O     . GLY A 1 117 ? 109.154 128.977 150.924 1.00 65.06  ? 117 GLY A O     1 
ATOM 411  N N     . VAL A 1 118 ? 111.347 129.313 150.582 1.00 66.21  ? 118 VAL A N     1 
ATOM 412  C CA    . VAL A 1 118 ? 111.202 129.195 149.131 1.00 66.21  ? 118 VAL A CA    1 
ATOM 413  C C     . VAL A 1 118 ? 110.654 127.819 148.739 1.00 66.21  ? 118 VAL A C     1 
ATOM 414  O O     . VAL A 1 118 ? 111.143 126.791 149.210 1.00 66.21  ? 118 VAL A O     1 
ATOM 415  C CB    . VAL A 1 118 ? 112.535 129.542 148.417 1.00 66.21  ? 118 VAL A CB    1 
ATOM 416  C CG1   . VAL A 1 118 ? 113.721 128.920 149.136 1.00 66.21  ? 118 VAL A CG1   1 
ATOM 417  C CG2   . VAL A 1 118 ? 112.510 129.155 146.947 1.00 66.21  ? 118 VAL A CG2   1 
ATOM 418  N N     . PRO A 1 119 ? 109.621 127.792 147.878 1.00 70.41  ? 119 PRO A N     1 
ATOM 419  C CA    . PRO A 1 119 ? 108.988 126.520 147.495 1.00 70.41  ? 119 PRO A CA    1 
ATOM 420  C C     . PRO A 1 119 ? 109.812 125.615 146.593 1.00 70.41  ? 119 PRO A C     1 
ATOM 421  O O     . PRO A 1 119 ? 110.543 126.111 145.735 1.00 70.41  ? 119 PRO A O     1 
ATOM 422  C CB    . PRO A 1 119 ? 107.722 126.969 146.749 1.00 70.41  ? 119 PRO A CB    1 
ATOM 423  C CG    . PRO A 1 119 ? 107.492 128.380 147.176 1.00 70.41  ? 119 PRO A CG    1 
ATOM 424  C CD    . PRO A 1 119 ? 108.859 128.953 147.389 1.00 70.41  ? 119 PRO A CD    1 
ATOM 425  N N     . THR A 1 120 ? 109.679 124.304 146.765 1.00 80.15  ? 120 THR A N     1 
ATOM 426  C CA    . THR A 1 120 ? 110.382 123.358 145.901 1.00 80.15  ? 120 THR A CA    1 
ATOM 427  C C     . THR A 1 120 ? 109.389 122.523 145.105 1.00 80.15  ? 120 THR A C     1 
ATOM 428  O O     . THR A 1 120 ? 108.425 121.994 145.660 1.00 80.15  ? 120 THR A O     1 
ATOM 429  C CB    . THR A 1 120 ? 111.325 122.433 146.696 1.00 80.15  ? 120 THR A CB    1 
ATOM 430  O OG1   . THR A 1 120 ? 111.563 121.235 145.946 1.00 80.15  ? 120 THR A OG1   1 
ATOM 431  C CG2   . THR A 1 120 ? 110.722 122.072 148.046 1.00 80.15  ? 120 THR A CG2   1 
ATOM 432  N N     . HIS A 1 121 ? 109.609 122.415 143.801 1.00 73.90  ? 121 HIS A N     1 
ATOM 433  C CA    . HIS A 1 121 ? 108.704 121.651 142.950 1.00 73.90  ? 121 HIS A CA    1 
ATOM 434  C C     . HIS A 1 121 ? 109.119 120.191 142.887 1.00 73.90  ? 121 HIS A C     1 
ATOM 435  O O     . HIS A 1 121 ? 109.596 119.725 141.851 1.00 73.90  ? 121 HIS A O     1 
ATOM 436  C CB    . HIS A 1 121 ? 108.664 122.248 141.543 1.00 73.90  ? 121 HIS A CB    1 
ATOM 437  C CG    . HIS A 1 121 ? 108.141 123.650 141.497 1.00 73.90  ? 121 HIS A CG    1 
ATOM 438  N ND1   . HIS A 1 121 ? 106.887 123.961 141.017 1.00 73.90  ? 121 HIS A ND1   1 
ATOM 439  C CD2   . HIS A 1 121 ? 108.699 124.824 141.876 1.00 73.90  ? 121 HIS A CD2   1 
ATOM 440  C CE1   . HIS A 1 121 ? 106.697 125.265 141.098 1.00 73.90  ? 121 HIS A CE1   1 
ATOM 441  N NE2   . HIS A 1 121 ? 107.782 125.812 141.617 1.00 73.90  ? 121 HIS A NE2   1 
ATOM 442  N N     . GLY A 1 122 ? 108.944 119.468 143.989 1.00 77.22  ? 122 GLY A N     1 
ATOM 443  C CA    . GLY A 1 122 ? 109.296 118.059 144.026 1.00 77.22  ? 122 GLY A CA    1 
ATOM 444  C C     . GLY A 1 122 ? 110.736 117.781 143.644 1.00 77.22  ? 122 GLY A C     1 
ATOM 445  O O     . GLY A 1 122 ? 111.021 116.789 142.974 1.00 77.22  ? 122 GLY A O     1 
ATOM 446  N N     . TYR A 1 123 ? 111.649 118.651 144.062 1.00 80.44  ? 123 TYR A N     1 
ATOM 447  C CA    . TYR A 1 123 ? 113.054 118.468 143.727 1.00 80.44  ? 123 TYR A CA    1 
ATOM 448  C C     . TYR A 1 123 ? 113.905 118.337 144.978 1.00 80.44  ? 123 TYR A C     1 
ATOM 449  O O     . TYR A 1 123 ? 113.850 119.196 145.858 1.00 80.44  ? 123 TYR A O     1 
ATOM 450  C CB    . TYR A 1 123 ? 113.550 119.627 142.865 1.00 80.44  ? 123 TYR A CB    1 
ATOM 451  C CG    . TYR A 1 123 ? 114.507 119.193 141.784 1.00 80.44  ? 123 TYR A CG    1 
ATOM 452  C CD1   . TYR A 1 123 ? 114.038 118.715 140.570 1.00 80.44  ? 123 TYR A CD1   1 
ATOM 453  C CD2   . TYR A 1 123 ? 115.878 119.250 141.981 1.00 80.44  ? 123 TYR A CD2   1 
ATOM 454  C CE1   . TYR A 1 123 ? 114.910 118.310 139.580 1.00 80.44  ? 123 TYR A CE1   1 
ATOM 455  C CE2   . TYR A 1 123 ? 116.757 118.852 140.997 1.00 80.44  ? 123 TYR A CE2   1 
ATOM 456  C CZ    . TYR A 1 123 ? 116.267 118.381 139.800 1.00 80.44  ? 123 TYR A CZ    1 
ATOM 457  O OH    . TYR A 1 123 ? 117.139 117.982 138.819 1.00 80.44  ? 123 TYR A OH    1 
ATOM 458  N N     . THR A 1 124 ? 114.704 117.276 145.055 1.00 80.61  ? 124 THR A N     1 
ATOM 459  C CA    . THR A 1 124 ? 115.535 117.043 146.235 1.00 80.61  ? 124 THR A CA    1 
ATOM 460  C C     . THR A 1 124 ? 116.919 116.519 145.873 1.00 80.61  ? 124 THR A C     1 
ATOM 461  O O     . THR A 1 124 ? 117.653 116.061 146.750 1.00 80.61  ? 124 THR A O     1 
ATOM 462  C CB    . THR A 1 124 ? 114.892 116.019 147.194 1.00 80.61  ? 124 THR A CB    1 
ATOM 463  O OG1   . THR A 1 124 ? 114.302 114.957 146.434 1.00 80.61  ? 124 THR A OG1   1 
ATOM 464  C CG2   . THR A 1 124 ? 113.823 116.670 148.062 1.00 80.61  ? 124 THR A CG2   1 
ATOM 465  N N     . THR A 1 125 ? 117.283 116.576 144.595 1.00 79.10  ? 125 THR A N     1 
ATOM 466  C CA    . THR A 1 125 ? 118.565 116.027 144.177 1.00 79.10  ? 125 THR A CA    1 
ATOM 467  C C     . THR A 1 125 ? 119.699 116.855 144.769 1.00 79.10  ? 125 THR A C     1 
ATOM 468  O O     . THR A 1 125 ? 119.689 118.086 144.677 1.00 79.10  ? 125 THR A O     1 
ATOM 469  C CB    . THR A 1 125 ? 118.673 115.993 142.654 1.00 79.10  ? 125 THR A CB    1 
ATOM 470  O OG1   . THR A 1 125 ? 117.440 115.515 142.101 1.00 79.10  ? 125 THR A OG1   1 
ATOM 471  C CG2   . THR A 1 125 ? 119.807 115.077 142.221 1.00 79.10  ? 125 THR A CG2   1 
ATOM 472  N N     . VAL A 1 126 ? 120.674 116.171 145.373 1.00 77.86  ? 126 VAL A N     1 
ATOM 473  C CA    . VAL A 1 126 ? 121.769 116.861 146.053 1.00 77.86  ? 126 VAL A CA    1 
ATOM 474  C C     . VAL A 1 126 ? 122.594 117.669 145.060 1.00 77.86  ? 126 VAL A C     1 
ATOM 475  O O     . VAL A 1 126 ? 123.097 118.751 145.383 1.00 77.86  ? 126 VAL A O     1 
ATOM 476  C CB    . VAL A 1 126 ? 122.637 115.846 146.818 1.00 77.86  ? 126 VAL A CB    1 
ATOM 477  C CG1   . VAL A 1 126 ? 123.829 116.532 147.460 1.00 77.86  ? 126 VAL A CG1   1 
ATOM 478  C CG2   . VAL A 1 126 ? 121.805 115.138 147.866 1.00 77.86  ? 126 VAL A CG2   1 
ATOM 479  N N     . GLN A 1 127 ? 122.753 117.155 143.841 1.00 78.77  ? 127 GLN A N     1 
ATOM 480  C CA    . GLN A 1 127 ? 123.491 117.894 142.823 1.00 78.77  ? 127 GLN A CA    1 
ATOM 481  C C     . GLN A 1 127 ? 122.617 118.953 142.168 1.00 78.77  ? 127 GLN A C     1 
ATOM 482  O O     . GLN A 1 127 ? 123.074 120.074 141.916 1.00 78.77  ? 127 GLN A O     1 
ATOM 483  C CB    . GLN A 1 127 ? 124.039 116.931 141.773 1.00 78.77  ? 127 GLN A CB    1 
ATOM 484  C CG    . GLN A 1 127 ? 125.413 116.377 142.089 1.00 78.77  ? 127 GLN A CG    1 
ATOM 485  C CD    . GLN A 1 127 ? 125.613 114.987 141.528 1.00 78.77  ? 127 GLN A CD    1 
ATOM 486  O OE1   . GLN A 1 127 ? 124.651 114.267 141.263 1.00 78.77  ? 127 GLN A OE1   1 
ATOM 487  N NE2   . GLN A 1 127 ? 126.868 114.600 141.343 1.00 78.77  ? 127 GLN A NE2   1 
ATOM 488  N N     . GLY A 1 128 ? 121.357 118.618 141.885 1.00 79.17  ? 128 GLY A N     1 
ATOM 489  C CA    . GLY A 1 128 ? 120.474 119.541 141.194 1.00 79.17  ? 128 GLY A CA    1 
ATOM 490  C C     . GLY A 1 128 ? 120.156 120.800 141.971 1.00 79.17  ? 128 GLY A C     1 
ATOM 491  O O     . GLY A 1 128 ? 119.670 121.771 141.383 1.00 79.17  ? 128 GLY A O     1 
ATOM 492  N N     . LEU A 1 129 ? 120.414 120.804 143.276 1.00 77.45  ? 129 LEU A N     1 
ATOM 493  C CA    . LEU A 1 129 ? 120.235 121.986 144.102 1.00 77.45  ? 129 LEU A CA    1 
ATOM 494  C C     . LEU A 1 129 ? 121.555 122.600 144.538 1.00 77.45  ? 129 LEU A C     1 
ATOM 495  O O     . LEU A 1 129 ? 121.551 123.659 145.171 1.00 77.45  ? 129 LEU A O     1 
ATOM 496  C CB    . LEU A 1 129 ? 119.383 121.646 145.328 1.00 77.45  ? 129 LEU A CB    1 
ATOM 497  C CG    . LEU A 1 129 ? 118.104 120.875 145.006 1.00 77.45  ? 129 LEU A CG    1 
ATOM 498  C CD1   . LEU A 1 129 ? 117.401 120.437 146.279 1.00 77.45  ? 129 LEU A CD1   1 
ATOM 499  C CD2   . LEU A 1 129 ? 117.189 121.728 144.154 1.00 77.45  ? 129 LEU A CD2   1 
ATOM 500  N N     . ASN A 1 130 ? 122.681 122.011 144.146 1.00 79.55  ? 130 ASN A N     1 
ATOM 501  C CA    . ASN A 1 130 ? 123.980 122.627 144.441 1.00 79.55  ? 130 ASN A CA    1 
ATOM 502  C C     . ASN A 1 130 ? 124.529 123.289 143.185 1.00 79.55  ? 130 ASN A C     1 
ATOM 503  O O     . ASN A 1 130 ? 125.488 124.050 143.256 1.00 79.55  ? 130 ASN A O     1 
ATOM 504  C CB    . ASN A 1 130 ? 124.960 121.606 145.011 1.00 79.55  ? 130 ASN A CB    1 
ATOM 505  C CG    . ASN A 1 130 ? 124.721 121.340 146.483 1.00 79.55  ? 130 ASN A CG    1 
ATOM 506  O OD1   . ASN A 1 130 ? 124.379 122.245 147.242 1.00 79.55  ? 130 ASN A OD1   1 
ATOM 507  N ND2   . ASN A 1 130 ? 124.887 120.092 146.892 1.00 79.55  ? 130 ASN A ND2   1 
ATOM 508  N N     . LEU A 1 131 ? 123.940 122.993 142.032 1.00 76.70  ? 131 LEU A N     1 
ATOM 509  C CA    . LEU A 1 131 ? 124.334 123.629 140.785 1.00 76.70  ? 131 LEU A CA    1 
ATOM 510  C C     . LEU A 1 131 ? 123.496 124.857 140.458 1.00 76.70  ? 131 LEU A C     1 
ATOM 511  O O     . LEU A 1 131 ? 123.772 125.528 139.459 1.00 76.70  ? 131 LEU A O     1 
ATOM 512  C CB    . LEU A 1 131 ? 124.246 122.622 139.634 1.00 76.70  ? 131 LEU A CB    1 
ATOM 513  C CG    . LEU A 1 131 ? 125.531 121.858 139.323 1.00 76.70  ? 131 LEU A CG    1 
ATOM 514  C CD1   . LEU A 1 131 ? 125.797 120.804 140.383 1.00 76.70  ? 131 LEU A CD1   1 
ATOM 515  C CD2   . LEU A 1 131 ? 125.459 121.228 137.942 1.00 76.70  ? 131 LEU A CD2   1 
ATOM 516  N N     . ILE A 1 132 ? 122.478 125.163 141.265 1.00 75.00  ? 132 ILE A N     1 
ATOM 517  C CA    . ILE A 1 132 ? 121.641 126.336 141.064 1.00 75.00  ? 132 ILE A CA    1 
ATOM 518  C C     . ILE A 1 132 ? 121.695 127.285 142.255 1.00 75.00  ? 132 ILE A C     1 
ATOM 519  O O     . ILE A 1 132 ? 121.706 128.508 142.076 1.00 75.00  ? 132 ILE A O     1 
ATOM 520  C CB    . ILE A 1 132 ? 120.181 125.940 140.741 1.00 75.00  ? 132 ILE A CB    1 
ATOM 521  C CG1   . ILE A 1 132 ? 119.558 125.131 141.879 1.00 75.00  ? 132 ILE A CG1   1 
ATOM 522  C CG2   . ILE A 1 132 ? 120.119 125.155 139.443 1.00 75.00  ? 132 ILE A CG2   1 
ATOM 523  C CD1   . ILE A 1 132 ? 118.074 124.891 141.711 1.00 75.00  ? 132 ILE A CD1   1 
ATOM 524  N N     . LEU A 1 133 ? 121.730 126.751 143.478 1.00 73.50  ? 133 LEU A N     1 
ATOM 525  C CA    . LEU A 1 133 ? 121.865 127.611 144.650 1.00 73.50  ? 133 LEU A CA    1 
ATOM 526  C C     . LEU A 1 133 ? 123.261 128.216 144.727 1.00 73.50  ? 133 LEU A C     1 
ATOM 527  O O     . LEU A 1 133 ? 123.416 129.419 144.969 1.00 73.50  ? 133 LEU A O     1 
ATOM 528  C CB    . LEU A 1 133 ? 121.553 126.824 145.922 1.00 73.50  ? 133 LEU A CB    1 
ATOM 529  C CG    . LEU A 1 133 ? 120.119 126.327 146.069 1.00 73.50  ? 133 LEU A CG    1 
ATOM 530  C CD1   . LEU A 1 133 ? 119.984 125.467 147.309 1.00 73.50  ? 133 LEU A CD1   1 
ATOM 531  C CD2   . LEU A 1 133 ? 119.164 127.496 146.101 1.00 73.50  ? 133 LEU A CD2   1 
ATOM 532  N N     . ARG A 1 134 ? 124.290 127.392 144.527 1.00 73.20  ? 134 ARG A N     1 
ATOM 533  C CA    . ARG A 1 134 ? 125.661 127.883 144.587 1.00 73.20  ? 134 ARG A CA    1 
ATOM 534  C C     . ARG A 1 134 ? 125.961 128.842 143.447 1.00 73.20  ? 134 ARG A C     1 
ATOM 535  O O     . ARG A 1 134 ? 126.748 129.779 143.618 1.00 73.20  ? 134 ARG A O     1 
ATOM 536  C CB    . ARG A 1 134 ? 126.630 126.702 144.569 1.00 73.20  ? 134 ARG A CB    1 
ATOM 537  C CG    . ARG A 1 134 ? 128.100 127.072 144.591 1.00 73.20  ? 134 ARG A CG    1 
ATOM 538  C CD    . ARG A 1 134 ? 128.957 125.819 144.575 1.00 73.20  ? 134 ARG A CD    1 
ATOM 539  N NE    . ARG A 1 134 ? 128.737 125.032 143.367 1.00 73.20  ? 134 ARG A NE    1 
ATOM 540  C CZ    . ARG A 1 134 ? 129.196 123.802 143.181 1.00 73.20  ? 134 ARG A CZ    1 
ATOM 541  N NH1   . ARG A 1 134 ? 129.910 123.183 144.107 1.00 73.20  ? 134 ARG A NH1   1 
ATOM 542  N NH2   . ARG A 1 134 ? 128.933 123.178 142.037 1.00 73.20  ? 134 ARG A NH2   1 
ATOM 543  N N     . HIS A 1 135 ? 125.357 128.622 142.280 1.00 76.60  ? 135 HIS A N     1 
ATOM 544  C CA    . HIS A 1 135 ? 125.536 129.555 141.174 1.00 76.60  ? 135 HIS A CA    1 
ATOM 545  C C     . HIS A 1 135 ? 124.860 130.890 141.459 1.00 76.60  ? 135 HIS A C     1 
ATOM 546  O O     . HIS A 1 135 ? 125.419 131.951 141.160 1.00 76.60  ? 135 HIS A O     1 
ATOM 547  C CB    . HIS A 1 135 ? 124.993 128.943 139.885 1.00 76.60  ? 135 HIS A CB    1 
ATOM 548  C CG    . HIS A 1 135 ? 126.043 128.310 139.029 1.00 76.60  ? 135 HIS A CG    1 
ATOM 549  N ND1   . HIS A 1 135 ? 126.057 126.962 138.745 1.00 76.60  ? 135 HIS A ND1   1 
ATOM 550  C CD2   . HIS A 1 135 ? 127.115 128.840 138.395 1.00 76.60  ? 135 HIS A CD2   1 
ATOM 551  C CE1   . HIS A 1 135 ? 127.093 126.689 137.973 1.00 76.60  ? 135 HIS A CE1   1 
ATOM 552  N NE2   . HIS A 1 135 ? 127.752 127.811 137.746 1.00 76.60  ? 135 HIS A NE2   1 
ATOM 553  N N     . THR A 1 136 ? 123.660 130.855 142.043 1.00 74.12  ? 136 THR A N     1 
ATOM 554  C CA    . THR A 1 136 ? 122.900 132.080 142.268 1.00 74.12  ? 136 THR A CA    1 
ATOM 555  C C     . THR A 1 136 ? 123.609 133.009 143.246 1.00 74.12  ? 136 THR A C     1 
ATOM 556  O O     . THR A 1 136 ? 123.626 134.230 143.047 1.00 74.12  ? 136 THR A O     1 
ATOM 557  C CB    . THR A 1 136 ? 121.500 131.738 142.773 1.00 74.12  ? 136 THR A CB    1 
ATOM 558  O OG1   . THR A 1 136 ? 120.786 131.025 141.756 1.00 74.12  ? 136 THR A OG1   1 
ATOM 559  C CG2   . THR A 1 136 ? 120.735 132.998 143.127 1.00 74.12  ? 136 THR A CG2   1 
ATOM 560  N N     . PHE A 1 137 ? 124.193 132.457 144.312 1.00 78.02  ? 137 PHE A N     1 
ATOM 561  C CA    . PHE A 1 137 ? 124.908 133.297 145.269 1.00 78.02  ? 137 PHE A CA    1 
ATOM 562  C C     . PHE A 1 137 ? 126.092 133.989 144.609 1.00 78.02  ? 137 PHE A C     1 
ATOM 563  O O     . PHE A 1 137 ? 126.362 135.165 144.876 1.00 78.02  ? 137 PHE A O     1 
ATOM 564  C CB    . PHE A 1 137 ? 125.363 132.467 146.467 1.00 78.02  ? 137 PHE A CB    1 
ATOM 565  C CG    . PHE A 1 137 ? 124.433 132.544 147.640 1.00 78.02  ? 137 PHE A CG    1 
ATOM 566  C CD1   . PHE A 1 137 ? 123.280 131.783 147.677 1.00 78.02  ? 137 PHE A CD1   1 
ATOM 567  C CD2   . PHE A 1 137 ? 124.712 133.380 148.706 1.00 78.02  ? 137 PHE A CD2   1 
ATOM 568  C CE1   . PHE A 1 137 ? 122.422 131.852 148.752 1.00 78.02  ? 137 PHE A CE1   1 
ATOM 569  C CE2   . PHE A 1 137 ? 123.857 133.453 149.787 1.00 78.02  ? 137 PHE A CE2   1 
ATOM 570  C CZ    . PHE A 1 137 ? 122.709 132.686 149.809 1.00 78.02  ? 137 PHE A CZ    1 
ATOM 571  N N     . ASN A 1 138 ? 126.811 133.275 143.741 1.00 82.80  ? 138 ASN A N     1 
ATOM 572  C CA    . ASN A 1 138 ? 127.860 133.910 142.957 1.00 82.80  ? 138 ASN A CA    1 
ATOM 573  C C     . ASN A 1 138 ? 127.295 134.874 141.924 1.00 82.80  ? 138 ASN A C     1 
ATOM 574  O O     . ASN A 1 138 ? 128.028 135.739 141.437 1.00 82.80  ? 138 ASN A O     1 
ATOM 575  C CB    . ASN A 1 138 ? 128.722 132.850 142.271 1.00 82.80  ? 138 ASN A CB    1 
ATOM 576  C CG    . ASN A 1 138 ? 130.197 133.197 142.291 1.00 82.80  ? 138 ASN A CG    1 
ATOM 577  O OD1   . ASN A 1 138 ? 130.572 134.357 142.459 1.00 82.80  ? 138 ASN A OD1   1 
ATOM 578  N ND2   . ASN A 1 138 ? 131.044 132.187 142.125 1.00 82.80  ? 138 ASN A ND2   1 
ATOM 579  N N     . ARG A 1 139 ? 126.017 134.731 141.564 1.00 81.86  ? 139 ARG A N     1 
ATOM 580  C CA    . ARG A 1 139 ? 125.370 135.723 140.711 1.00 81.86  ? 139 ARG A CA    1 
ATOM 581  C C     . ARG A 1 139 ? 125.006 136.975 141.501 1.00 81.86  ? 139 ARG A C     1 
ATOM 582  O O     . ARG A 1 139 ? 125.138 138.093 140.992 1.00 81.86  ? 139 ARG A O     1 
ATOM 583  C CB    . ARG A 1 139 ? 124.127 135.125 140.048 1.00 81.86  ? 139 ARG A CB    1 
ATOM 584  C CG    . ARG A 1 139 ? 124.429 134.130 138.937 1.00 81.86  ? 139 ARG A CG    1 
ATOM 585  C CD    . ARG A 1 139 ? 123.456 134.275 137.773 1.00 81.86  ? 139 ARG A CD    1 
ATOM 586  N NE    . ARG A 1 139 ? 122.076 134.004 138.158 1.00 81.86  ? 139 ARG A NE    1 
ATOM 587  C CZ    . ARG A 1 139 ? 121.435 132.871 137.904 1.00 81.86  ? 139 ARG A CZ    1 
ATOM 588  N NH1   . ARG A 1 139 ? 122.025 131.871 137.269 1.00 81.86  ? 139 ARG A NH1   1 
ATOM 589  N NH2   . ARG A 1 139 ? 120.170 132.738 138.293 1.00 81.86  ? 139 ARG A NH2   1 
ATOM 590  N N     . TYR A 1 140 ? 124.548 136.806 142.743 1.00 80.44  ? 140 TYR A N     1 
ATOM 591  C CA    . TYR A 1 140 ? 124.283 137.935 143.624 1.00 80.44  ? 140 TYR A CA    1 
ATOM 592  C C     . TYR A 1 140 ? 125.557 138.545 144.190 1.00 80.44  ? 140 TYR A C     1 
ATOM 593  O O     . TYR A 1 140 ? 125.526 139.686 144.661 1.00 80.44  ? 140 TYR A O     1 
ATOM 594  C CB    . TYR A 1 140 ? 123.362 137.505 144.768 1.00 80.44  ? 140 TYR A CB    1 
ATOM 595  C CG    . TYR A 1 140 ? 122.672 138.654 145.466 1.00 80.44  ? 140 TYR A CG    1 
ATOM 596  C CD1   . TYR A 1 140 ? 121.915 139.573 144.752 1.00 80.44  ? 140 TYR A CD1   1 
ATOM 597  C CD2   . TYR A 1 140 ? 122.773 138.816 146.841 1.00 80.44  ? 140 TYR A CD2   1 
ATOM 598  C CE1   . TYR A 1 140 ? 121.282 140.626 145.387 1.00 80.44  ? 140 TYR A CE1   1 
ATOM 599  C CE2   . TYR A 1 140 ? 122.143 139.864 147.485 1.00 80.44  ? 140 TYR A CE2   1 
ATOM 600  C CZ    . TYR A 1 140 ? 121.399 140.766 146.754 1.00 80.44  ? 140 TYR A CZ    1 
ATOM 601  O OH    . TYR A 1 140 ? 120.770 141.810 147.391 1.00 80.44  ? 140 TYR A OH    1 
ATOM 602  N N     . ASP A 1 141 ? 126.663 137.815 144.156 1.00 85.74  ? 141 ASP A N     1 
ATOM 603  C CA    . ASP A 1 141 ? 127.981 138.323 144.486 1.00 85.74  ? 141 ASP A CA    1 
ATOM 604  C C     . ASP A 1 141 ? 128.753 138.534 143.189 1.00 85.74  ? 141 ASP A C     1 
ATOM 605  O O     . ASP A 1 141 ? 128.206 138.405 142.089 1.00 85.74  ? 141 ASP A O     1 
ATOM 606  C CB    . ASP A 1 141 ? 128.700 137.364 145.437 1.00 85.74  ? 141 ASP A CB    1 
ATOM 607  C CG    . ASP A 1 141 ? 128.131 137.401 146.842 1.00 85.74  ? 141 ASP A CG    1 
ATOM 608  O OD1   . ASP A 1 141 ? 127.703 138.489 147.282 1.00 85.74  ? 141 ASP A OD1   1 
ATOM 609  O OD2   . ASP A 1 141 ? 128.113 136.344 147.506 1.00 85.74  ? 141 ASP A OD2   1 
ATOM 610  N N     . GLY A 1 142 ? 130.030 138.876 143.312 1.00 95.13  ? 142 GLY A N     1 
ATOM 611  C CA    . GLY A 1 142 ? 130.843 139.078 142.131 1.00 95.13  ? 142 GLY A CA    1 
ATOM 612  C C     . GLY A 1 142 ? 130.513 140.374 141.423 1.00 95.13  ? 142 GLY A C     1 
ATOM 613  O O     . GLY A 1 142 ? 131.401 141.192 141.176 1.00 95.13  ? 142 GLY A O     1 
ATOM 614  N N     . VAL A 1 143 ? 129.238 140.563 141.070 1.00 100.26 ? 143 VAL A N     1 
ATOM 615  C CA    . VAL A 1 143 ? 128.799 141.854 140.553 1.00 100.26 ? 143 VAL A CA    1 
ATOM 616  C C     . VAL A 1 143 ? 129.004 142.937 141.602 1.00 100.26 ? 143 VAL A C     1 
ATOM 617  O O     . VAL A 1 143 ? 129.390 144.065 141.275 1.00 100.26 ? 143 VAL A O     1 
ATOM 618  C CB    . VAL A 1 143 ? 127.332 141.780 140.084 1.00 100.26 ? 143 VAL A CB    1 
ATOM 619  C CG1   . VAL A 1 143 ? 127.235 141.010 138.776 1.00 100.26 ? 143 VAL A CG1   1 
ATOM 620  C CG2   . VAL A 1 143 ? 126.460 141.131 141.149 1.00 100.26 ? 143 VAL A CG2   1 
ATOM 621  N N     . ILE A 1 144 ? 128.746 142.618 142.872 1.00 99.86  ? 144 ILE A N     1 
ATOM 622  C CA    . ILE A 1 144 ? 129.140 143.515 143.951 1.00 99.86  ? 144 ILE A CA    1 
ATOM 623  C C     . ILE A 1 144 ? 130.654 143.660 143.978 1.00 99.86  ? 144 ILE A C     1 
ATOM 624  O O     . ILE A 1 144 ? 131.186 144.765 144.143 1.00 99.86  ? 144 ILE A O     1 
ATOM 625  C CB    . ILE A 1 144 ? 128.593 143.006 145.297 1.00 99.86  ? 144 ILE A CB    1 
ATOM 626  C CG1   . ILE A 1 144 ? 127.071 142.861 145.234 1.00 99.86  ? 144 ILE A CG1   1 
ATOM 627  C CG2   . ILE A 1 144 ? 128.996 143.943 146.426 1.00 99.86  ? 144 ILE A CG2   1 
ATOM 628  C CD1   . ILE A 1 144 ? 126.345 144.157 144.949 1.00 99.86  ? 144 ILE A CD1   1 
ATOM 629  N N     . LYS A 1 145 ? 131.373 142.547 143.812 1.00 98.09  ? 145 LYS A N     1 
ATOM 630  C CA    . LYS A 1 145 ? 132.818 142.625 143.649 1.00 98.09  ? 145 LYS A CA    1 
ATOM 631  C C     . LYS A 1 145 ? 133.188 143.350 142.364 1.00 98.09  ? 145 LYS A C     1 
ATOM 632  O O     . LYS A 1 145 ? 134.232 144.006 142.304 1.00 98.09  ? 145 LYS A O     1 
ATOM 633  C CB    . LYS A 1 145 ? 133.432 141.224 143.664 1.00 98.09  ? 145 LYS A CB    1 
ATOM 634  C CG    . LYS A 1 145 ? 133.656 140.643 145.055 1.00 98.09  ? 145 LYS A CG    1 
ATOM 635  C CD    . LYS A 1 145 ? 132.373 140.081 145.646 1.00 98.09  ? 145 LYS A CD    1 
ATOM 636  C CE    . LYS A 1 145 ? 132.632 139.396 146.978 1.00 98.09  ? 145 LYS A CE    1 
ATOM 637  N NZ    . LYS A 1 145 ? 131.371 138.930 147.618 1.00 98.09  ? 145 LYS A NZ    1 
ATOM 638  N N     . LYS A 1 146 ? 132.358 143.232 141.324 1.00 102.86 ? 146 LYS A N     1 
ATOM 639  C CA    . LYS A 1 146 ? 132.568 144.030 140.119 1.00 102.86 ? 146 LYS A CA    1 
ATOM 640  C C     . LYS A 1 146 ? 132.332 145.506 140.403 1.00 102.86 ? 146 LYS A C     1 
ATOM 641  O O     . LYS A 1 146 ? 133.034 146.371 139.865 1.00 102.86 ? 146 LYS A O     1 
ATOM 642  C CB    . LYS A 1 146 ? 131.656 143.545 138.994 1.00 102.86 ? 146 LYS A CB    1 
ATOM 643  C CG    . LYS A 1 146 ? 131.890 144.246 137.666 1.00 102.86 ? 146 LYS A CG    1 
ATOM 644  C CD    . LYS A 1 146 ? 133.291 143.976 137.143 1.00 102.86 ? 146 LYS A CD    1 
ATOM 645  C CE    . LYS A 1 146 ? 133.705 145.013 136.113 1.00 102.86 ? 146 LYS A CE    1 
ATOM 646  N NZ    . LYS A 1 146 ? 133.740 146.384 136.692 1.00 102.86 ? 146 LYS A NZ    1 
ATOM 647  N N     . VAL A 1 147 ? 131.337 145.814 141.236 1.00 106.02 ? 147 VAL A N     1 
ATOM 648  C CA    . VAL A 1 147 ? 131.213 147.166 141.770 1.00 106.02 ? 147 VAL A CA    1 
ATOM 649  C C     . VAL A 1 147 ? 132.442 147.508 142.600 1.00 106.02 ? 147 VAL A C     1 
ATOM 650  O O     . VAL A 1 147 ? 132.952 148.634 142.557 1.00 106.02 ? 147 VAL A O     1 
ATOM 651  C CB    . VAL A 1 147 ? 129.911 147.302 142.584 1.00 106.02 ? 147 VAL A CB    1 
ATOM 652  C CG1   . VAL A 1 147 ? 129.952 148.539 143.470 1.00 106.02 ? 147 VAL A CG1   1 
ATOM 653  C CG2   . VAL A 1 147 ? 128.707 147.342 141.656 1.00 106.02 ? 147 VAL A CG2   1 
ATOM 654  N N     . GLU A 1 148 ? 132.942 146.536 143.366 1.00 105.18 ? 148 GLU A N     1 
ATOM 655  C CA    . GLU A 1 148 ? 134.216 146.724 144.047 1.00 105.18 ? 148 GLU A CA    1 
ATOM 656  C C     . GLU A 1 148 ? 135.371 146.784 143.056 1.00 105.18 ? 148 GLU A C     1 
ATOM 657  O O     . GLU A 1 148 ? 136.323 147.545 143.264 1.00 105.18 ? 148 GLU A O     1 
ATOM 658  C CB    . GLU A 1 148 ? 134.436 145.603 145.065 1.00 105.18 ? 148 GLU A CB    1 
ATOM 659  C CG    . GLU A 1 148 ? 135.775 145.658 145.783 1.00 105.18 ? 148 GLU A CG    1 
ATOM 660  C CD    . GLU A 1 148 ? 136.784 144.682 145.210 1.00 105.18 ? 148 GLU A CD    1 
ATOM 661  O OE1   . GLU A 1 148 ? 136.374 143.777 144.453 1.00 105.18 ? 148 GLU A OE1   1 
ATOM 662  O OE2   . GLU A 1 148 ? 137.987 144.819 145.517 1.00 105.18 ? 148 GLU A OE2   1 
ATOM 663  N N     . THR A 1 149 ? 135.304 145.997 141.979 1.00 104.73 ? 149 THR A N     1 
ATOM 664  C CA    . THR A 1 149 ? 136.376 146.000 140.987 1.00 104.73 ? 149 THR A CA    1 
ATOM 665  C C     . THR A 1 149 ? 136.536 147.377 140.356 1.00 104.73 ? 149 THR A C     1 
ATOM 666  O O     . THR A 1 149 ? 137.655 147.891 140.240 1.00 104.73 ? 149 THR A O     1 
ATOM 667  C CB    . THR A 1 149 ? 136.102 144.947 139.912 1.00 104.73 ? 149 THR A CB    1 
ATOM 668  O OG1   . THR A 1 149 ? 136.026 143.651 140.518 1.00 104.73 ? 149 THR A OG1   1 
ATOM 669  C CG2   . THR A 1 149 ? 137.212 144.948 138.871 1.00 104.73 ? 149 THR A CG2   1 
ATOM 670  N N     . ARG A 1 150 ? 135.427 147.995 139.946 1.00 106.12 ? 150 ARG A N     1 
ATOM 671  C CA    . ARG A 1 150 ? 135.503 149.353 139.424 1.00 106.12 ? 150 ARG A CA    1 
ATOM 672  C C     . ARG A 1 150 ? 135.823 150.366 140.514 1.00 106.12 ? 150 ARG A C     1 
ATOM 673  O O     . ARG A 1 150 ? 136.248 151.482 140.197 1.00 106.12 ? 150 ARG A O     1 
ATOM 674  C CB    . ARG A 1 150 ? 134.196 149.731 138.723 1.00 106.12 ? 150 ARG A CB    1 
ATOM 675  C CG    . ARG A 1 150 ? 132.961 149.620 139.597 1.00 106.12 ? 150 ARG A CG    1 
ATOM 676  C CD    . ARG A 1 150 ? 131.739 150.203 138.906 1.00 106.12 ? 150 ARG A CD    1 
ATOM 677  N NE    . ARG A 1 150 ? 130.573 150.217 139.782 1.00 106.12 ? 150 ARG A NE    1 
ATOM 678  C CZ    . ARG A 1 150 ? 130.258 151.218 140.594 1.00 106.12 ? 150 ARG A CZ    1 
ATOM 679  N NH1   . ARG A 1 150 ? 131.004 152.308 140.669 1.00 106.12 ? 150 ARG A NH1   1 
ATOM 680  N NH2   . ARG A 1 150 ? 129.167 151.122 141.349 1.00 106.12 ? 150 ARG A NH2   1 
ATOM 681  N N     . ASN A 1 151 ? 135.627 149.999 141.779 1.00 104.19 ? 151 ASN A N     1 
ATOM 682  C CA    . ASN A 1 151 ? 135.959 150.850 142.918 1.00 104.19 ? 151 ASN A CA    1 
ATOM 683  C C     . ASN A 1 151 ? 135.248 152.198 142.846 1.00 104.19 ? 151 ASN A C     1 
ATOM 684  O O     . ASN A 1 151 ? 134.103 152.281 142.402 1.00 104.19 ? 151 ASN A O     1 
ATOM 685  C CB    . ASN A 1 151 ? 137.474 151.055 143.006 1.00 104.19 ? 151 ASN A CB    1 
ATOM 686  C CG    . ASN A 1 151 ? 137.918 151.538 144.371 1.00 104.19 ? 151 ASN A CG    1 
ATOM 687  O OD1   . ASN A 1 151 ? 137.169 151.462 145.343 1.00 104.19 ? 151 ASN A OD1   1 
ATOM 688  N ND2   . ASN A 1 151 ? 139.147 152.035 144.451 1.00 104.19 ? 151 ASN A ND2   1 
ATOM 689  N N     . PRO A 1 192 ? 121.971 139.576 135.879 1.00 91.41  ? 192 PRO A N     1 
ATOM 690  C CA    . PRO A 1 192 ? 120.648 139.880 136.436 1.00 91.41  ? 192 PRO A CA    1 
ATOM 691  C C     . PRO A 1 192 ? 119.569 138.953 135.890 1.00 91.41  ? 192 PRO A C     1 
ATOM 692  O O     . PRO A 1 192 ? 118.576 138.690 136.567 1.00 91.41  ? 192 PRO A O     1 
ATOM 693  C CB    . PRO A 1 192 ? 120.390 141.325 135.989 1.00 91.41  ? 192 PRO A CB    1 
ATOM 694  C CG    . PRO A 1 192 ? 121.706 141.857 135.536 1.00 91.41  ? 192 PRO A CG    1 
ATOM 695  C CD    . PRO A 1 192 ? 122.513 140.689 135.082 1.00 91.41  ? 192 PRO A CD    1 
ATOM 696  N N     . GLY A 1 193 ? 119.779 138.465 134.669 1.00 81.36  ? 193 GLY A N     1 
ATOM 697  C CA    . GLY A 1 193 ? 118.769 137.670 133.994 1.00 81.36  ? 193 GLY A CA    1 
ATOM 698  C C     . GLY A 1 193 ? 118.450 136.394 134.746 1.00 81.36  ? 193 GLY A C     1 
ATOM 699  O O     . GLY A 1 193 ? 119.347 135.720 135.263 1.00 81.36  ? 193 GLY A O     1 
ATOM 700  N N     . ILE A 1 194 ? 117.163 136.057 134.803 1.00 73.18  ? 194 ILE A N     1 
ATOM 701  C CA    . ILE A 1 194 ? 116.717 134.801 135.392 1.00 73.18  ? 194 ILE A CA    1 
ATOM 702  C C     . ILE A 1 194 ? 116.966 133.700 134.373 1.00 73.18  ? 194 ILE A C     1 
ATOM 703  O O     . ILE A 1 194 ? 116.115 133.423 133.520 1.00 73.18  ? 194 ILE A O     1 
ATOM 704  C CB    . ILE A 1 194 ? 115.233 134.863 135.794 1.00 73.18  ? 194 ILE A CB    1 
ATOM 705  C CG1   . ILE A 1 194 ? 114.935 136.165 136.540 1.00 73.18  ? 194 ILE A CG1   1 
ATOM 706  C CG2   . ILE A 1 194 ? 114.849 133.650 136.620 1.00 73.18  ? 194 ILE A CG2   1 
ATOM 707  C CD1   . ILE A 1 194 ? 115.520 136.225 137.926 1.00 73.18  ? 194 ILE A CD1   1 
ATOM 708  N N     . ASN A 1 195 ? 118.133 133.073 134.451 1.00 75.83  ? 195 ASN A N     1 
ATOM 709  C CA    . ASN A 1 195 ? 118.554 132.118 133.435 1.00 75.83  ? 195 ASN A CA    1 
ATOM 710  C C     . ASN A 1 195 ? 117.871 130.777 133.646 1.00 75.83  ? 195 ASN A C     1 
ATOM 711  O O     . ASN A 1 195 ? 118.001 130.191 134.728 1.00 75.83  ? 195 ASN A O     1 
ATOM 712  C CB    . ASN A 1 195 ? 120.060 131.930 133.477 1.00 75.83  ? 195 ASN A CB    1 
ATOM 713  C CG    . ASN A 1 195 ? 120.798 133.064 132.826 1.00 75.83  ? 195 ASN A CG    1 
ATOM 714  O OD1   . ASN A 1 195 ? 120.614 133.337 131.642 1.00 75.83  ? 195 ASN A OD1   1 
ATOM 715  N ND2   . ASN A 1 195 ? 121.639 133.742 133.598 1.00 75.83  ? 195 ASN A ND2   1 
ATOM 716  N N     . PRO A 1 196 ? 117.140 130.256 132.663 1.00 67.00  ? 196 PRO A N     1 
ATOM 717  C CA    . PRO A 1 196 ? 116.702 128.861 132.756 1.00 67.00  ? 196 PRO A CA    1 
ATOM 718  C C     . PRO A 1 196 ? 117.771 127.916 132.235 1.00 67.00  ? 196 PRO A C     1 
ATOM 719  O O     . PRO A 1 196 ? 117.454 126.906 131.607 1.00 67.00  ? 196 PRO A O     1 
ATOM 720  C CB    . PRO A 1 196 ? 115.457 128.825 131.866 1.00 67.00  ? 196 PRO A CB    1 
ATOM 721  C CG    . PRO A 1 196 ? 115.709 129.895 130.859 1.00 67.00  ? 196 PRO A CG    1 
ATOM 722  C CD    . PRO A 1 196 ? 116.456 130.980 131.579 1.00 67.00  ? 196 PRO A CD    1 
ATOM 723  N N     . SER A 1 197 ? 119.036 128.198 132.533 1.00 65.01  ? 197 SER A N     1 
ATOM 724  C CA    . SER A 1 197 ? 120.139 127.397 132.007 1.00 65.01  ? 197 SER A CA    1 
ATOM 725  C C     . SER A 1 197 ? 120.233 126.140 132.855 1.00 65.01  ? 197 SER A C     1 
ATOM 726  O O     . SER A 1 197 ? 120.870 126.117 133.909 1.00 65.01  ? 197 SER A O     1 
ATOM 727  C CB    . SER A 1 197 ? 121.441 128.187 132.017 1.00 65.01  ? 197 SER A CB    1 
ATOM 728  O OG    . SER A 1 197 ? 121.440 129.189 131.019 1.00 65.01  ? 197 SER A OG    1 
ATOM 729  N N     . ILE A 1 198 ? 119.583 125.078 132.389 1.00 62.13  ? 198 ILE A N     1 
ATOM 730  C CA    . ILE A 1 198 ? 119.510 123.845 133.158 1.00 62.13  ? 198 ILE A CA    1 
ATOM 731  C C     . ILE A 1 198 ? 120.861 123.155 133.093 1.00 62.13  ? 198 ILE A C     1 
ATOM 732  O O     . ILE A 1 198 ? 121.174 122.455 132.124 1.00 62.13  ? 198 ILE A O     1 
ATOM 733  C CB    . ILE A 1 198 ? 118.386 122.932 132.642 1.00 62.13  ? 198 ILE A CB    1 
ATOM 734  C CG1   . ILE A 1 198 ? 117.068 123.698 132.616 1.00 62.13  ? 198 ILE A CG1   1 
ATOM 735  C CG2   . ILE A 1 198 ? 118.265 121.699 133.510 1.00 62.13  ? 198 ILE A CG2   1 
ATOM 736  C CD1   . ILE A 1 198 ? 115.897 122.872 132.176 1.00 62.13  ? 198 ILE A CD1   1 
ATOM 737  N N     . TYR A 1 199 ? 121.669 123.352 134.129 1.00 65.21  ? 199 TYR A N     1 
ATOM 738  C CA    . TYR A 1 199 ? 123.001 122.764 134.207 1.00 65.21  ? 199 TYR A CA    1 
ATOM 739  C C     . TYR A 1 199 ? 122.852 121.297 134.586 1.00 65.21  ? 199 TYR A C     1 
ATOM 740  O O     . TYR A 1 199 ? 122.676 120.962 135.760 1.00 65.21  ? 199 TYR A O     1 
ATOM 741  C CB    . TYR A 1 199 ? 123.855 123.513 135.222 1.00 65.21  ? 199 TYR A CB    1 
ATOM 742  C CG    . TYR A 1 199 ? 124.424 124.816 134.718 1.00 65.21  ? 199 TYR A CG    1 
ATOM 743  C CD1   . TYR A 1 199 ? 125.549 124.838 133.911 1.00 65.21  ? 199 TYR A CD1   1 
ATOM 744  C CD2   . TYR A 1 199 ? 123.842 126.026 135.060 1.00 65.21  ? 199 TYR A CD2   1 
ATOM 745  C CE1   . TYR A 1 199 ? 126.076 126.028 133.453 1.00 65.21  ? 199 TYR A CE1   1 
ATOM 746  C CE2   . TYR A 1 199 ? 124.360 127.221 134.607 1.00 65.21  ? 199 TYR A CE2   1 
ATOM 747  C CZ    . TYR A 1 199 ? 125.477 127.217 133.805 1.00 65.21  ? 199 TYR A CZ    1 
ATOM 748  O OH    . TYR A 1 199 ? 125.997 128.406 133.351 1.00 65.21  ? 199 TYR A OH    1 
ATOM 749  N N     . CYS A 1 200 ? 122.917 120.415 133.593 1.00 72.55  ? 200 CYS A N     1 
ATOM 750  C CA    . CYS A 1 200 ? 122.836 118.990 133.866 1.00 72.55  ? 200 CYS A CA    1 
ATOM 751  C C     . CYS A 1 200 ? 124.090 118.524 134.599 1.00 72.55  ? 200 CYS A C     1 
ATOM 752  O O     . CYS A 1 200 ? 125.144 119.163 134.556 1.00 72.55  ? 200 CYS A O     1 
ATOM 753  C CB    . CYS A 1 200 ? 122.648 118.202 132.573 1.00 72.55  ? 200 CYS A CB    1 
ATOM 754  S SG    . CYS A 1 200 ? 120.993 118.330 131.860 1.00 72.55  ? 200 CYS A SG    1 
ATOM 755  N N     . TYR A 1 201 ? 123.965 117.391 135.283 1.00 75.93  ? 201 TYR A N     1 
ATOM 756  C CA    . TYR A 1 201 ? 124.996 116.929 136.199 1.00 75.93  ? 201 TYR A CA    1 
ATOM 757  C C     . TYR A 1 201 ? 125.324 115.476 135.881 1.00 75.93  ? 201 TYR A C     1 
ATOM 758  O O     . TYR A 1 201 ? 124.906 114.932 134.854 1.00 75.93  ? 201 TYR A O     1 
ATOM 759  C CB    . TYR A 1 201 ? 124.544 117.114 137.652 1.00 75.93  ? 201 TYR A CB    1 
ATOM 760  C CG    . TYR A 1 201 ? 123.077 116.842 137.869 1.00 75.93  ? 201 TYR A CG    1 
ATOM 761  C CD1   . TYR A 1 201 ? 122.603 115.545 137.995 1.00 75.93  ? 201 TYR A CD1   1 
ATOM 762  C CD2   . TYR A 1 201 ? 122.165 117.882 137.950 1.00 75.93  ? 201 TYR A CD2   1 
ATOM 763  C CE1   . TYR A 1 201 ? 121.263 115.292 138.196 1.00 75.93  ? 201 TYR A CE1   1 
ATOM 764  C CE2   . TYR A 1 201 ? 120.827 117.641 138.151 1.00 75.93  ? 201 TYR A CE2   1 
ATOM 765  C CZ    . TYR A 1 201 ? 120.379 116.345 138.271 1.00 75.93  ? 201 TYR A CZ    1 
ATOM 766  O OH    . TYR A 1 201 ? 119.040 116.099 138.470 1.00 75.93  ? 201 TYR A OH    1 
ATOM 767  N N     . GLN A 1 202 ? 126.091 114.853 136.777 1.00 77.61  ? 202 GLN A N     1 
ATOM 768  C CA    . GLN A 1 202 ? 126.545 113.484 136.560 1.00 77.61  ? 202 GLN A CA    1 
ATOM 769  C C     . GLN A 1 202 ? 125.377 112.512 136.459 1.00 77.61  ? 202 GLN A C     1 
ATOM 770  O O     . GLN A 1 202 ? 125.370 111.628 135.595 1.00 77.61  ? 202 GLN A O     1 
ATOM 771  C CB    . GLN A 1 202 ? 127.484 113.065 137.688 1.00 77.61  ? 202 GLN A CB    1 
ATOM 772  C CG    . GLN A 1 202 ? 127.862 111.596 137.683 1.00 77.61  ? 202 GLN A CG    1 
ATOM 773  C CD    . GLN A 1 202 ? 129.057 111.300 138.565 1.00 77.61  ? 202 GLN A CD    1 
ATOM 774  O OE1   . GLN A 1 202 ? 129.094 111.685 139.732 1.00 77.61  ? 202 GLN A OE1   1 
ATOM 775  N NE2   . GLN A 1 202 ? 130.042 110.606 138.010 1.00 77.61  ? 202 GLN A NE2   1 
ATOM 776  N N     . GLN A 1 203 ? 124.382 112.657 137.332 1.00 80.21  ? 203 GLN A N     1 
ATOM 777  C CA    . GLN A 1 203 ? 123.295 111.690 137.396 1.00 80.21  ? 203 GLN A CA    1 
ATOM 778  C C     . GLN A 1 203 ? 122.401 111.713 136.164 1.00 80.21  ? 203 GLN A C     1 
ATOM 779  O O     . GLN A 1 203 ? 121.610 110.782 135.982 1.00 80.21  ? 203 GLN A O     1 
ATOM 780  C CB    . GLN A 1 203 ? 122.450 111.938 138.645 1.00 80.21  ? 203 GLN A CB    1 
ATOM 781  C CG    . GLN A 1 203 ? 123.182 111.670 139.947 1.00 80.21  ? 203 GLN A CG    1 
ATOM 782  C CD    . GLN A 1 203 ? 122.322 111.943 141.162 1.00 80.21  ? 203 GLN A CD    1 
ATOM 783  O OE1   . GLN A 1 203 ? 122.741 111.715 142.296 1.00 80.21  ? 203 GLN A OE1   1 
ATOM 784  N NE2   . GLN A 1 203 ? 121.108 112.428 140.932 1.00 80.21  ? 203 GLN A NE2   1 
ATOM 785  N N     . VAL A 1 204 ? 122.504 112.739 135.323 1.00 75.90  ? 204 VAL A N     1 
ATOM 786  C CA    . VAL A 1 204 ? 121.660 112.858 134.140 1.00 75.90  ? 204 VAL A CA    1 
ATOM 787  C C     . VAL A 1 204 ? 122.536 112.931 132.896 1.00 75.90  ? 204 VAL A C     1 
ATOM 788  O O     . VAL A 1 204 ? 122.189 113.600 131.916 1.00 75.90  ? 204 VAL A O     1 
ATOM 789  C CB    . VAL A 1 204 ? 120.732 114.080 134.243 1.00 75.90  ? 204 VAL A CB    1 
ATOM 790  C CG1   . VAL A 1 204 ? 119.709 113.871 135.344 1.00 75.90  ? 204 VAL A CG1   1 
ATOM 791  C CG2   . VAL A 1 204 ? 121.540 115.335 134.510 1.00 75.90  ? 204 VAL A CG2   1 
ATOM 792  N N     . SER A 1 205 ? 123.675 112.248 132.931 1.00 73.39  ? 205 SER A N     1 
ATOM 793  C CA    . SER A 1 205 ? 124.603 112.282 131.811 1.00 73.39  ? 205 SER A CA    1 
ATOM 794  C C     . SER A 1 205 ? 123.949 111.684 130.566 1.00 73.39  ? 205 SER A C     1 
ATOM 795  O O     . SER A 1 205 ? 123.169 110.731 130.672 1.00 73.39  ? 205 SER A O     1 
ATOM 796  C CB    . SER A 1 205 ? 125.881 111.515 132.155 1.00 73.39  ? 205 SER A CB    1 
ATOM 797  O OG    . SER A 1 205 ? 126.787 111.505 131.066 1.00 73.39  ? 205 SER A OG    1 
ATOM 798  N N     . PRO A 1 206 ? 124.230 112.225 129.381 1.00 69.95  ? 206 PRO A N     1 
ATOM 799  C CA    . PRO A 1 206 ? 123.595 111.700 128.166 1.00 69.95  ? 206 PRO A CA    1 
ATOM 800  C C     . PRO A 1 206 ? 124.056 110.286 127.854 1.00 69.95  ? 206 PRO A C     1 
ATOM 801  O O     . PRO A 1 206 ? 125.209 109.919 128.088 1.00 69.95  ? 206 PRO A O     1 
ATOM 802  C CB    . PRO A 1 206 ? 124.044 112.682 127.076 1.00 69.95  ? 206 PRO A CB    1 
ATOM 803  C CG    . PRO A 1 206 ? 124.571 113.879 127.806 1.00 69.95  ? 206 PRO A CG    1 
ATOM 804  C CD    . PRO A 1 206 ? 125.115 113.364 129.093 1.00 69.95  ? 206 PRO A CD    1 
ATOM 805  N N     . VAL A 1 207 ? 123.137 109.492 127.318 1.00 70.54  ? 207 VAL A N     1 
ATOM 806  C CA    . VAL A 1 207 ? 123.452 108.161 126.807 1.00 70.54  ? 207 VAL A CA    1 
ATOM 807  C C     . VAL A 1 207 ? 122.794 108.015 125.439 1.00 70.54  ? 207 VAL A C     1 
ATOM 808  O O     . VAL A 1 207 ? 121.763 108.653 125.182 1.00 70.54  ? 207 VAL A O     1 
ATOM 809  C CB    . VAL A 1 207 ? 122.991 107.059 127.775 1.00 70.54  ? 207 VAL A CB    1 
ATOM 810  C CG1   . VAL A 1 207 ? 123.805 107.101 129.061 1.00 70.54  ? 207 VAL A CG1   1 
ATOM 811  C CG2   . VAL A 1 207 ? 121.509 107.202 128.078 1.00 70.54  ? 207 VAL A CG2   1 
ATOM 812  N N     . PRO A 1 208 ? 123.355 107.219 124.531 1.00 66.30  ? 208 PRO A N     1 
ATOM 813  C CA    . PRO A 1 208 ? 122.717 107.028 123.225 1.00 66.30  ? 208 PRO A CA    1 
ATOM 814  C C     . PRO A 1 208 ? 121.342 106.388 123.355 1.00 66.30  ? 208 PRO A C     1 
ATOM 815  O O     . PRO A 1 208 ? 121.080 105.605 124.269 1.00 66.30  ? 208 PRO A O     1 
ATOM 816  C CB    . PRO A 1 208 ? 123.700 106.117 122.482 1.00 66.30  ? 208 PRO A CB    1 
ATOM 817  C CG    . PRO A 1 208 ? 125.013 106.389 123.122 1.00 66.30  ? 208 PRO A CG    1 
ATOM 818  C CD    . PRO A 1 208 ? 124.716 106.659 124.568 1.00 66.30  ? 208 PRO A CD    1 
ATOM 819  N N     . TYR A 1 209 ? 120.463 106.733 122.418 1.00 72.99  ? 209 TYR A N     1 
ATOM 820  C CA    . TYR A 1 209 ? 119.073 106.308 122.469 1.00 72.99  ? 209 TYR A CA    1 
ATOM 821  C C     . TYR A 1 209 ? 118.941 104.803 122.271 1.00 72.99  ? 209 TYR A C     1 
ATOM 822  O O     . TYR A 1 209 ? 119.748 104.164 121.592 1.00 72.99  ? 209 TYR A O     1 
ATOM 823  C CB    . TYR A 1 209 ? 118.261 107.041 121.402 1.00 72.99  ? 209 TYR A CB    1 
ATOM 824  C CG    . TYR A 1 209 ? 116.794 106.673 121.360 1.00 72.99  ? 209 TYR A CG    1 
ATOM 825  C CD1   . TYR A 1 209 ? 115.870 107.332 122.161 1.00 72.99  ? 209 TYR A CD1   1 
ATOM 826  C CD2   . TYR A 1 209 ? 116.330 105.675 120.511 1.00 72.99  ? 209 TYR A CD2   1 
ATOM 827  C CE1   . TYR A 1 209 ? 114.529 107.003 122.124 1.00 72.99  ? 209 TYR A CE1   1 
ATOM 828  C CE2   . TYR A 1 209 ? 114.990 105.339 120.468 1.00 72.99  ? 209 TYR A CE2   1 
ATOM 829  C CZ    . TYR A 1 209 ? 114.094 106.006 121.277 1.00 72.99  ? 209 TYR A CZ    1 
ATOM 830  O OH    . TYR A 1 209 ? 112.759 105.676 121.238 1.00 72.99  ? 209 TYR A OH    1 
ATOM 831  N N     . ASN A 1 210 ? 117.899 104.243 122.878 1.00 75.21  ? 210 ASN A N     1 
ATOM 832  C CA    . ASN A 1 210 ? 117.523 102.850 122.705 1.00 75.21  ? 210 ASN A CA    1 
ATOM 833  C C     . ASN A 1 210 ? 116.008 102.765 122.751 1.00 75.21  ? 210 ASN A C     1 
ATOM 834  O O     . ASN A 1 210 ? 115.365 103.596 123.403 1.00 75.21  ? 210 ASN A O     1 
ATOM 835  C CB    . ASN A 1 210 ? 118.140 101.958 123.791 1.00 75.21  ? 210 ASN A CB    1 
ATOM 836  C CG    . ASN A 1 210 ? 117.553 102.220 125.161 1.00 75.21  ? 210 ASN A CG    1 
ATOM 837  O OD1   . ASN A 1 210 ? 117.300 103.365 125.532 1.00 75.21  ? 210 ASN A OD1   1 
ATOM 838  N ND2   . ASN A 1 210 ? 117.328 101.156 125.921 1.00 75.21  ? 210 ASN A ND2   1 
ATOM 839  N N     . PRO A 1 211 ? 115.404 101.780 122.070 1.00 80.38  ? 211 PRO A N     1 
ATOM 840  C CA    . PRO A 1 211 ? 113.948 101.604 122.104 1.00 80.38  ? 211 PRO A CA    1 
ATOM 841  C C     . PRO A 1 211 ? 113.430 101.259 123.497 1.00 80.38  ? 211 PRO A C     1 
ATOM 842  O O     . PRO A 1 211 ? 114.180 100.692 124.292 1.00 80.38  ? 211 PRO A O     1 
ATOM 843  C CB    . PRO A 1 211 ? 113.710 100.439 121.135 1.00 80.38  ? 211 PRO A CB    1 
ATOM 844  C CG    . PRO A 1 211 ? 114.915 100.418 120.256 1.00 80.38  ? 211 PRO A CG    1 
ATOM 845  C CD    . PRO A 1 211 ? 116.050 100.850 121.129 1.00 80.38  ? 211 PRO A CD    1 
ATOM 846  N N     . LEU A 1 228 ? 130.483 104.359 113.153 1.00 80.53  ? 228 LEU A N     1 
ATOM 847  C CA    . LEU A 1 228 ? 129.423 105.227 112.651 1.00 80.53  ? 228 LEU A CA    1 
ATOM 848  C C     . LEU A 1 228 ? 129.400 105.234 111.128 1.00 80.53  ? 228 LEU A C     1 
ATOM 849  O O     . LEU A 1 228 ? 130.447 105.144 110.487 1.00 80.53  ? 228 LEU A O     1 
ATOM 850  C CB    . LEU A 1 228 ? 129.597 106.650 113.183 1.00 80.53  ? 228 LEU A CB    1 
ATOM 851  C CG    . LEU A 1 228 ? 129.506 106.801 114.701 1.00 80.53  ? 228 LEU A CG    1 
ATOM 852  C CD1   . LEU A 1 228 ? 129.358 108.256 115.075 1.00 80.53  ? 228 LEU A CD1   1 
ATOM 853  C CD2   . LEU A 1 228 ? 128.349 105.988 115.255 1.00 80.53  ? 228 LEU A CD2   1 
ATOM 854  N N     . PRO A 1 229 ? 128.203 105.331 110.551 1.00 81.44  ? 229 PRO A N     1 
ATOM 855  C CA    . PRO A 1 229 ? 128.085 105.361 109.089 1.00 81.44  ? 229 PRO A CA    1 
ATOM 856  C C     . PRO A 1 229 ? 128.777 106.579 108.496 1.00 81.44  ? 229 PRO A C     1 
ATOM 857  O O     . PRO A 1 229 ? 128.869 107.649 109.103 1.00 81.44  ? 229 PRO A O     1 
ATOM 858  C CB    . PRO A 1 229 ? 126.571 105.406 108.855 1.00 81.44  ? 229 PRO A CB    1 
ATOM 859  C CG    . PRO A 1 229 ? 125.976 104.840 110.106 1.00 81.44  ? 229 PRO A CG    1 
ATOM 860  C CD    . PRO A 1 229 ? 126.889 105.265 111.213 1.00 81.44  ? 229 PRO A CD    1 
ATOM 861  N N     . LEU A 1 230 ? 129.273 106.399 107.272 1.00 82.19  ? 230 LEU A N     1 
ATOM 862  C CA    . LEU A 1 230 ? 129.950 107.464 106.545 1.00 82.19  ? 230 LEU A CA    1 
ATOM 863  C C     . LEU A 1 230 ? 128.985 108.489 105.964 1.00 82.19  ? 230 LEU A C     1 
ATOM 864  O O     . LEU A 1 230 ? 129.413 109.596 105.619 1.00 82.19  ? 230 LEU A O     1 
ATOM 865  C CB    . LEU A 1 230 ? 130.806 106.856 105.427 1.00 82.19  ? 230 LEU A CB    1 
ATOM 866  C CG    . LEU A 1 230 ? 131.634 107.767 104.516 1.00 82.19  ? 230 LEU A CG    1 
ATOM 867  C CD1   . LEU A 1 230 ? 132.627 108.587 105.320 1.00 82.19  ? 230 LEU A CD1   1 
ATOM 868  C CD2   . LEU A 1 230 ? 132.348 106.951 103.448 1.00 82.19  ? 230 LEU A CD2   1 
ATOM 869  N N     . GLY A 1 231 ? 127.701 108.164 105.875 1.00 85.86  ? 231 GLY A N     1 
ATOM 870  C CA    . GLY A 1 231 ? 126.752 109.071 105.248 1.00 85.86  ? 231 GLY A CA    1 
ATOM 871  C C     . GLY A 1 231 ? 126.553 108.696 103.799 1.00 85.86  ? 231 GLY A C     1 
ATOM 872  O O     . GLY A 1 231 ? 126.056 107.610 103.491 1.00 85.86  ? 231 GLY A O     1 
ATOM 873  N N     . THR A 1 232 ? 126.930 109.600 102.898 1.00 83.53  ? 232 THR A N     1 
ATOM 874  C CA    . THR A 1 232 ? 126.950 109.288 101.475 1.00 83.53  ? 232 THR A CA    1 
ATOM 875  C C     . THR A 1 232 ? 128.315 108.710 101.120 1.00 83.53  ? 232 THR A C     1 
ATOM 876  O O     . THR A 1 232 ? 129.296 109.458 101.011 1.00 83.53  ? 232 THR A O     1 
ATOM 877  C CB    . THR A 1 232 ? 126.655 110.529 100.631 1.00 83.53  ? 232 THR A CB    1 
ATOM 878  O OG1   . THR A 1 232 ? 127.565 111.577 100.985 1.00 83.53  ? 232 THR A OG1   1 
ATOM 879  C CG2   . THR A 1 232 ? 125.228 111.003 100.861 1.00 83.53  ? 232 THR A CG2   1 
ATOM 880  N N     . PRO A 1 233 ? 128.422 107.390 100.945 1.00 85.32  ? 233 PRO A N     1 
ATOM 881  C CA    . PRO A 1 233 ? 129.742 106.794 100.683 1.00 85.32  ? 233 PRO A CA    1 
ATOM 882  C C     . PRO A 1 233 ? 130.379 107.273 99.395  1.00 85.32  ? 233 PRO A C     1 
ATOM 883  O O     . PRO A 1 233 ? 131.611 107.361 99.318  1.00 85.32  ? 233 PRO A O     1 
ATOM 884  C CB    . PRO A 1 233 ? 129.441 105.290 100.640 1.00 85.32  ? 233 PRO A CB    1 
ATOM 885  C CG    . PRO A 1 233 ? 128.008 105.207 100.239 1.00 85.32  ? 233 PRO A CG    1 
ATOM 886  C CD    . PRO A 1 233 ? 127.336 106.399 100.857 1.00 85.32  ? 233 PRO A CD    1 
ATOM 887  N N     . ASN A 1 234 ? 129.581 107.589 98.380  1.00 86.75  ? 234 ASN A N     1 
ATOM 888  C CA    . ASN A 1 234 ? 130.083 107.989 97.074  1.00 86.75  ? 234 ASN A CA    1 
ATOM 889  C C     . ASN A 1 234 ? 129.498 109.342 96.704  1.00 86.75  ? 234 ASN A C     1 
ATOM 890  O O     . ASN A 1 234 ? 128.284 109.545 96.806  1.00 86.75  ? 234 ASN A O     1 
ATOM 891  C CB    . ASN A 1 234 ? 129.723 106.946 96.015  1.00 86.75  ? 234 ASN A CB    1 
ATOM 892  C CG    . ASN A 1 234 ? 129.942 105.529 96.499  1.00 86.75  ? 234 ASN A CG    1 
ATOM 893  O OD1   . ASN A 1 234 ? 128.994 104.827 96.849  1.00 86.75  ? 234 ASN A OD1   1 
ATOM 894  N ND2   . ASN A 1 234 ? 131.198 105.098 96.520  1.00 86.75  ? 234 ASN A ND2   1 
ATOM 895  N N     . ARG A 1 235 ? 130.359 110.266 96.275  1.00 85.23  ? 235 ARG A N     1 
ATOM 896  C CA    . ARG A 1 235 ? 129.885 111.569 95.822  1.00 85.23  ? 235 ARG A CA    1 
ATOM 897  C C     . ARG A 1 235 ? 129.465 111.522 94.357  1.00 85.23  ? 235 ARG A C     1 
ATOM 898  O O     . ARG A 1 235 ? 128.295 111.746 94.035  1.00 85.23  ? 235 ARG A O     1 
ATOM 899  C CB    . ARG A 1 235 ? 130.961 112.639 96.037  1.00 85.23  ? 235 ARG A CB    1 
ATOM 900  C CG    . ARG A 1 235 ? 130.470 114.054 95.764  1.00 85.23  ? 235 ARG A CG    1 
ATOM 901  C CD    . ARG A 1 235 ? 131.618 115.044 95.702  1.00 85.23  ? 235 ARG A CD    1 
ATOM 902  N NE    . ARG A 1 235 ? 132.238 115.244 97.006  1.00 85.23  ? 235 ARG A NE    1 
ATOM 903  C CZ    . ARG A 1 235 ? 131.951 116.246 97.826  1.00 85.23  ? 235 ARG A CZ    1 
ATOM 904  N NH1   . ARG A 1 235 ? 131.051 117.163 97.509  1.00 85.23  ? 235 ARG A NH1   1 
ATOM 905  N NH2   . ARG A 1 235 ? 132.582 116.330 98.994  1.00 85.23  ? 235 ARG A NH2   1 
ATOM 906  N N     . LEU A 1 236 ? 130.397 111.202 93.463  1.00 81.98  ? 236 LEU A N     1 
ATOM 907  C CA    . LEU A 1 236 ? 130.078 111.124 92.038  1.00 81.98  ? 236 LEU A CA    1 
ATOM 908  C C     . LEU A 1 236 ? 129.631 109.722 91.638  1.00 81.98  ? 236 LEU A C     1 
ATOM 909  O O     . LEU A 1 236 ? 130.104 109.161 90.651  1.00 81.98  ? 236 LEU A O     1 
ATOM 910  C CB    . LEU A 1 236 ? 131.280 111.564 91.213  1.00 81.98  ? 236 LEU A CB    1 
ATOM 911  C CG    . LEU A 1 236 ? 132.142 112.693 91.778  1.00 81.98  ? 236 LEU A CG    1 
ATOM 912  C CD1   . LEU A 1 236 ? 133.396 112.879 90.937  1.00 81.98  ? 236 LEU A CD1   1 
ATOM 913  C CD2   . LEU A 1 236 ? 131.348 113.987 91.856  1.00 81.98  ? 236 LEU A CD2   1 
ATOM 914  N N     . SER A 1 237 ? 128.706 109.143 92.408  1.00 81.88  ? 237 SER A N     1 
ATOM 915  C CA    . SER A 1 237 ? 128.099 107.868 92.029  1.00 81.88  ? 237 SER A CA    1 
ATOM 916  C C     . SER A 1 237 ? 126.765 107.745 92.765  1.00 81.88  ? 237 SER A C     1 
ATOM 917  O O     . SER A 1 237 ? 126.739 107.329 93.926  1.00 81.88  ? 237 SER A O     1 
ATOM 918  C CB    . SER A 1 237 ? 129.020 106.702 92.350  1.00 81.88  ? 237 SER A CB    1 
ATOM 919  O OG    . SER A 1 237 ? 128.311 105.474 92.336  1.00 81.88  ? 237 SER A OG    1 
ATOM 920  N N     . ILE A 1 238 ? 125.679 108.067 92.072  1.00 78.91  ? 238 ILE A N     1 
ATOM 921  C CA    . ILE A 1 238 ? 124.317 107.890 92.572  1.00 78.91  ? 238 ILE A CA    1 
ATOM 922  C C     . ILE A 1 238 ? 123.426 107.700 91.350  1.00 78.91  ? 238 ILE A C     1 
ATOM 923  O O     . ILE A 1 238 ? 123.641 108.369 90.328  1.00 78.91  ? 238 ILE A O     1 
ATOM 924  C CB    . ILE A 1 238 ? 123.858 109.084 93.429  1.00 78.91  ? 238 ILE A CB    1 
ATOM 925  C CG1   . ILE A 1 238 ? 124.397 108.983 94.858  1.00 78.91  ? 238 ILE A CG1   1 
ATOM 926  C CG2   . ILE A 1 238 ? 122.341 109.173 93.478  1.00 78.91  ? 238 ILE A CG2   1 
ATOM 927  C CD1   . ILE A 1 238 ? 124.172 110.228 95.686  1.00 78.91  ? 238 ILE A CD1   1 
ATOM 928  N N     . PRO A 1 239 ? 122.443 106.800 91.387  1.00 82.75  ? 239 PRO A N     1 
ATOM 929  C CA    . PRO A 1 239 ? 121.552 106.640 90.232  1.00 82.75  ? 239 PRO A CA    1 
ATOM 930  C C     . PRO A 1 239 ? 120.839 107.942 89.898  1.00 82.75  ? 239 PRO A C     1 
ATOM 931  O O     . PRO A 1 239 ? 120.435 108.697 90.785  1.00 82.75  ? 239 PRO A O     1 
ATOM 932  C CB    . PRO A 1 239 ? 120.569 105.558 90.688  1.00 82.75  ? 239 PRO A CB    1 
ATOM 933  C CG    . PRO A 1 239 ? 121.311 104.792 91.732  1.00 82.75  ? 239 PRO A CG    1 
ATOM 934  C CD    . PRO A 1 239 ? 122.187 105.792 92.431  1.00 82.75  ? 239 PRO A CD    1 
ATOM 935  N N     . LYS A 1 240 ? 120.693 108.200 88.601  1.00 82.41  ? 240 LYS A N     1 
ATOM 936  C CA    . LYS A 1 240 ? 120.108 109.452 88.142  1.00 82.41  ? 240 LYS A CA    1 
ATOM 937  C C     . LYS A 1 240 ? 118.634 109.534 88.517  1.00 82.41  ? 240 LYS A C     1 
ATOM 938  O O     . LYS A 1 240 ? 117.876 108.575 88.347  1.00 82.41  ? 240 LYS A O     1 
ATOM 939  C CB    . LYS A 1 240 ? 120.275 109.587 86.628  1.00 82.41  ? 240 LYS A CB    1 
ATOM 940  C CG    . LYS A 1 240 ? 119.503 110.742 86.010  1.00 82.41  ? 240 LYS A CG    1 
ATOM 941  C CD    . LYS A 1 240 ? 119.784 110.862 84.520  1.00 82.41  ? 240 LYS A CD    1 
ATOM 942  C CE    . LYS A 1 240 ? 118.969 111.982 83.893  1.00 82.41  ? 240 LYS A CE    1 
ATOM 943  N NZ    . LYS A 1 240 ? 117.506 111.775 84.078  1.00 82.41  ? 240 LYS A NZ    1 
ATOM 944  N N     . GLY A 1 241 ? 118.228 110.696 89.032  1.00 83.33  ? 241 GLY A N     1 
ATOM 945  C CA    . GLY A 1 241 ? 116.858 110.970 89.392  1.00 83.33  ? 241 GLY A CA    1 
ATOM 946  C C     . GLY A 1 241 ? 116.539 110.726 90.854  1.00 83.33  ? 241 GLY A C     1 
ATOM 947  O O     . GLY A 1 241 ? 115.610 111.344 91.388  1.00 83.33  ? 241 GLY A O     1 
ATOM 948  N N     . GLN A 1 242 ? 117.283 109.841 91.510  1.00 84.94  ? 242 GLN A N     1 
ATOM 949  C CA    . GLN A 1 242 ? 117.090 109.614 92.931  1.00 84.94  ? 242 GLN A CA    1 
ATOM 950  C C     . GLN A 1 242 ? 117.577 110.826 93.724  1.00 84.94  ? 242 GLN A C     1 
ATOM 951  O O     . GLN A 1 242 ? 118.401 111.604 93.237  1.00 84.94  ? 242 GLN A O     1 
ATOM 952  C CB    . GLN A 1 242 ? 117.836 108.358 93.376  1.00 84.94  ? 242 GLN A CB    1 
ATOM 953  C CG    . GLN A 1 242 ? 117.405 107.093 92.651  1.00 84.94  ? 242 GLN A CG    1 
ATOM 954  C CD    . GLN A 1 242 ? 118.122 105.858 93.158  1.00 84.94  ? 242 GLN A CD    1 
ATOM 955  O OE1   . GLN A 1 242 ? 119.001 105.944 94.016  1.00 84.94  ? 242 GLN A OE1   1 
ATOM 956  N NE2   . GLN A 1 242 ? 117.750 104.698 92.628  1.00 84.94  ? 242 GLN A NE2   1 
ATOM 957  N N     . PRO A 1 243 ? 117.068 111.021 94.942  1.00 83.40  ? 243 PRO A N     1 
ATOM 958  C CA    . PRO A 1 243 ? 117.545 112.140 95.763  1.00 83.40  ? 243 PRO A CA    1 
ATOM 959  C C     . PRO A 1 243 ? 119.040 112.038 96.023  1.00 83.40  ? 243 PRO A C     1 
ATOM 960  O O     . PRO A 1 243 ? 119.585 110.949 96.211  1.00 83.40  ? 243 PRO A O     1 
ATOM 961  C CB    . PRO A 1 243 ? 116.736 112.003 97.060  1.00 83.40  ? 243 PRO A CB    1 
ATOM 962  C CG    . PRO A 1 243 ? 116.184 110.610 97.040  1.00 83.40  ? 243 PRO A CG    1 
ATOM 963  C CD    . PRO A 1 243 ? 115.980 110.280 95.600  1.00 83.40  ? 243 PRO A CD    1 
ATOM 964  N N     . GLY A 1 244 ? 119.702 113.192 96.029  1.00 81.19  ? 244 GLY A N     1 
ATOM 965  C CA    . GLY A 1 244 ? 121.134 113.255 96.205  1.00 81.19  ? 244 GLY A CA    1 
ATOM 966  C C     . GLY A 1 244 ? 121.939 113.109 94.932  1.00 81.19  ? 244 GLY A C     1 
ATOM 967  O O     . GLY A 1 244 ? 123.167 113.262 94.976  1.00 81.19  ? 244 GLY A O     1 
ATOM 968  N N     . TYR A 1 245 ? 121.290 112.825 93.804  1.00 77.26  ? 245 TYR A N     1 
ATOM 969  C CA    . TYR A 1 245 ? 122.007 112.570 92.562  1.00 77.26  ? 245 TYR A CA    1 
ATOM 970  C C     . TYR A 1 245 ? 122.757 113.814 92.111  1.00 77.26  ? 245 TYR A C     1 
ATOM 971  O O     . TYR A 1 245 ? 122.185 114.903 92.027  1.00 77.26  ? 245 TYR A O     1 
ATOM 972  C CB    . TYR A 1 245 ? 121.027 112.111 91.481  1.00 77.26  ? 245 TYR A CB    1 
ATOM 973  C CG    . TYR A 1 245 ? 121.572 112.162 90.073  1.00 77.26  ? 245 TYR A CG    1 
ATOM 974  C CD1   . TYR A 1 245 ? 122.677 111.406 89.705  1.00 77.26  ? 245 TYR A CD1   1 
ATOM 975  C CD2   . TYR A 1 245 ? 120.973 112.957 89.107  1.00 77.26  ? 245 TYR A CD2   1 
ATOM 976  C CE1   . TYR A 1 245 ? 123.172 111.448 88.416  1.00 77.26  ? 245 TYR A CE1   1 
ATOM 977  C CE2   . TYR A 1 245 ? 121.464 113.006 87.818  1.00 77.26  ? 245 TYR A CE2   1 
ATOM 978  C CZ    . TYR A 1 245 ? 122.561 112.249 87.479  1.00 77.26  ? 245 TYR A CZ    1 
ATOM 979  O OH    . TYR A 1 245 ? 123.049 112.297 86.195  1.00 77.26  ? 245 TYR A OH    1 
ATOM 980  N N     . VAL A 1 246 ? 124.040 113.645 91.817  1.00 73.88  ? 246 VAL A N     1 
ATOM 981  C CA    . VAL A 1 246 ? 124.894 114.758 91.411  1.00 73.88  ? 246 VAL A CA    1 
ATOM 982  C C     . VAL A 1 246 ? 124.529 115.168 89.989  1.00 73.88  ? 246 VAL A C     1 
ATOM 983  O O     . VAL A 1 246 ? 123.927 114.373 89.253  1.00 73.88  ? 246 VAL A O     1 
ATOM 984  C CB    . VAL A 1 246 ? 126.380 114.389 91.545  1.00 73.88  ? 246 VAL A CB    1 
ATOM 985  C CG1   . VAL A 1 246 ? 126.729 114.186 93.004  1.00 73.88  ? 246 VAL A CG1   1 
ATOM 986  C CG2   . VAL A 1 246 ? 126.686 113.139 90.749  1.00 73.88  ? 246 VAL A CG2   1 
ATOM 987  N N     . PRO A 1 247 ? 124.848 116.388 89.565  1.00 74.23  ? 247 PRO A N     1 
ATOM 988  C CA    . PRO A 1 247 ? 124.389 116.850 88.254  1.00 74.23  ? 247 PRO A CA    1 
ATOM 989  C C     . PRO A 1 247 ? 125.121 116.159 87.117  1.00 74.23  ? 247 PRO A C     1 
ATOM 990  O O     . PRO A 1 247 ? 126.161 115.522 87.294  1.00 74.23  ? 247 PRO A O     1 
ATOM 991  C CB    . PRO A 1 247 ? 124.698 118.347 88.281  1.00 74.23  ? 247 PRO A CB    1 
ATOM 992  C CG    . PRO A 1 247 ? 125.837 118.472 89.211  1.00 74.23  ? 247 PRO A CG    1 
ATOM 993  C CD    . PRO A 1 247 ? 125.644 117.415 90.258  1.00 74.23  ? 247 PRO A CD    1 
ATOM 994  N N     . GLU A 1 248 ? 124.545 116.297 85.925  1.00 81.09  ? 248 GLU A N     1 
ATOM 995  C CA    . GLU A 1 248 ? 125.107 115.712 84.718  1.00 81.09  ? 248 GLU A CA    1 
ATOM 996  C C     . GLU A 1 248 ? 125.823 116.729 83.839  1.00 81.09  ? 248 GLU A C     1 
ATOM 997  O O     . GLU A 1 248 ? 126.688 116.338 83.048  1.00 81.09  ? 248 GLU A O     1 
ATOM 998  C CB    . GLU A 1 248 ? 123.998 115.024 83.906  1.00 81.09  ? 248 GLU A CB    1 
ATOM 999  C CG    . GLU A 1 248 ? 124.482 114.224 82.705  1.00 81.09  ? 248 GLU A CG    1 
ATOM 1000 C CD    . GLU A 1 248 ? 125.117 112.905 83.100  1.00 81.09  ? 248 GLU A CD    1 
ATOM 1001 O OE1   . GLU A 1 248 ? 124.875 112.442 84.234  1.00 81.09  ? 248 GLU A OE1   1 
ATOM 1002 O OE2   . GLU A 1 248 ? 125.861 112.332 82.276  1.00 81.09  ? 248 GLU A OE2   1 
ATOM 1003 N N     . TRP A 1 249 ? 125.501 118.019 83.967  1.00 81.19  ? 249 TRP A N     1 
ATOM 1004 C CA    . TRP A 1 249 ? 126.119 119.013 83.096  1.00 81.19  ? 249 TRP A CA    1 
ATOM 1005 C C     . TRP A 1 249 ? 127.618 119.127 83.343  1.00 81.19  ? 249 TRP A C     1 
ATOM 1006 O O     . TRP A 1 249 ? 128.382 119.357 82.399  1.00 81.19  ? 249 TRP A O     1 
ATOM 1007 C CB    . TRP A 1 249 ? 125.435 120.374 83.257  1.00 81.19  ? 249 TRP A CB    1 
ATOM 1008 C CG    . TRP A 1 249 ? 125.419 120.949 84.646  1.00 81.19  ? 249 TRP A CG    1 
ATOM 1009 C CD1   . TRP A 1 249 ? 124.735 120.474 85.721  1.00 81.19  ? 249 TRP A CD1   1 
ATOM 1010 C CD2   . TRP A 1 249 ? 126.089 122.137 85.090  1.00 81.19  ? 249 TRP A CD2   1 
ATOM 1011 N NE1   . TRP A 1 249 ? 124.951 121.277 86.814  1.00 81.19  ? 249 TRP A NE1   1 
ATOM 1012 C CE2   . TRP A 1 249 ? 125.779 122.306 86.452  1.00 81.19  ? 249 TRP A CE2   1 
ATOM 1013 C CE3   . TRP A 1 249 ? 126.927 123.067 84.470  1.00 81.19  ? 249 TRP A CE3   1 
ATOM 1014 C CZ2   . TRP A 1 249 ? 126.279 123.365 87.204  1.00 81.19  ? 249 TRP A CZ2   1 
ATOM 1015 C CZ3   . TRP A 1 249 ? 127.422 124.118 85.220  1.00 81.19  ? 249 TRP A CZ3   1 
ATOM 1016 C CH2   . TRP A 1 249 ? 127.097 124.258 86.571  1.00 81.19  ? 249 TRP A CH2   1 
ATOM 1017 N N     . GLN A 1 250 ? 128.060 118.969 84.588  1.00 74.96  ? 250 GLN A N     1 
ATOM 1018 C CA    . GLN A 1 250 ? 129.491 118.942 84.881  1.00 74.96  ? 250 GLN A CA    1 
ATOM 1019 C C     . GLN A 1 250 ? 129.713 118.167 86.174  1.00 74.96  ? 250 GLN A C     1 
ATOM 1020 O O     . GLN A 1 250 ? 129.322 118.613 87.255  1.00 74.96  ? 250 GLN A O     1 
ATOM 1021 C CB    . GLN A 1 250 ? 130.071 120.366 84.928  1.00 74.96  ? 250 GLN A CB    1 
ATOM 1022 C CG    . GLN A 1 250 ? 129.546 121.332 86.002  1.00 74.96  ? 250 GLN A CG    1 
ATOM 1023 C CD    . GLN A 1 250 ? 130.238 121.192 87.346  1.00 74.96  ? 250 GLN A CD    1 
ATOM 1024 O OE1   . GLN A 1 250 ? 131.450 121.368 87.454  1.00 74.96  ? 250 GLN A OE1   1 
ATOM 1025 N NE2   . GLN A 1 250 ? 129.470 120.855 88.376  1.00 74.96  ? 250 GLN A NE2   1 
ATOM 1026 N N     . ARG A 1 251 ? 130.250 116.961 86.047  1.00 76.37  ? 251 ARG A N     1 
ATOM 1027 C CA    . ARG A 1 251 ? 130.761 116.218 87.192  1.00 76.37  ? 251 ARG A CA    1 
ATOM 1028 C C     . ARG A 1 251 ? 132.191 116.640 87.527  1.00 76.37  ? 251 ARG A C     1 
ATOM 1029 O O     . ARG A 1 251 ? 132.516 116.788 88.711  1.00 76.37  ? 251 ARG A O     1 
ATOM 1030 C CB    . ARG A 1 251 ? 130.671 114.711 86.952  1.00 76.37  ? 251 ARG A CB    1 
ATOM 1031 C CG    . ARG A 1 251 ? 129.252 114.178 87.048  1.00 76.37  ? 251 ARG A CG    1 
ATOM 1032 C CD    . ARG A 1 251 ? 129.220 112.700 87.374  1.00 76.37  ? 251 ARG A CD    1 
ATOM 1033 N NE    . ARG A 1 251 ? 127.875 112.247 87.703  1.00 76.37  ? 251 ARG A NE    1 
ATOM 1034 C CZ    . ARG A 1 251 ? 127.591 111.058 88.215  1.00 76.37  ? 251 ARG A CZ    1 
ATOM 1035 N NH1   . ARG A 1 251 ? 128.539 110.173 88.474  1.00 76.37  ? 251 ARG A NH1   1 
ATOM 1036 N NH2   . ARG A 1 251 ? 126.325 110.751 88.478  1.00 76.37  ? 251 ARG A NH2   1 
ATOM 1037 N N     . PRO A 1 252 ? 133.088 116.840 86.533  1.00 81.16  ? 252 PRO A N     1 
ATOM 1038 C CA    . PRO A 1 252 ? 134.429 117.343 86.867  1.00 81.16  ? 252 PRO A CA    1 
ATOM 1039 C C     . PRO A 1 252 ? 134.424 118.807 87.275  1.00 81.16  ? 252 PRO A C     1 
ATOM 1040 O O     . PRO A 1 252 ? 133.358 119.398 87.475  1.00 81.16  ? 252 PRO A O     1 
ATOM 1041 C CB    . PRO A 1 252 ? 135.222 117.129 85.571  1.00 81.16  ? 252 PRO A CB    1 
ATOM 1042 C CG    . PRO A 1 252 ? 134.198 117.103 84.506  1.00 81.16  ? 252 PRO A CG    1 
ATOM 1043 C CD    . PRO A 1 252 ? 133.024 116.415 85.121  1.00 81.16  ? 252 PRO A CD    1 
ATOM 1044 N N     . HIS A 1 253 ? 135.621 119.379 87.431  1.00 88.71  ? 253 HIS A N     1 
ATOM 1045 C CA    . HIS A 1 253 ? 135.847 120.773 87.811  1.00 88.71  ? 253 HIS A CA    1 
ATOM 1046 C C     . HIS A 1 253 ? 135.499 121.053 89.268  1.00 88.71  ? 253 HIS A C     1 
ATOM 1047 O O     . HIS A 1 253 ? 135.268 122.208 89.640  1.00 88.71  ? 253 HIS A O     1 
ATOM 1048 C CB    . HIS A 1 253 ? 135.086 121.742 86.896  1.00 88.71  ? 253 HIS A CB    1 
ATOM 1049 C CG    . HIS A 1 253 ? 135.521 121.688 85.464  1.00 88.71  ? 253 HIS A CG    1 
ATOM 1050 N ND1   . HIS A 1 253 ? 136.716 122.219 85.028  1.00 88.71  ? 253 HIS A ND1   1 
ATOM 1051 C CD2   . HIS A 1 253 ? 134.920 121.167 84.369  1.00 88.71  ? 253 HIS A CD2   1 
ATOM 1052 C CE1   . HIS A 1 253 ? 136.832 122.026 83.727  1.00 88.71  ? 253 HIS A CE1   1 
ATOM 1053 N NE2   . HIS A 1 253 ? 135.756 121.390 83.302  1.00 88.71  ? 253 HIS A NE2   1 
ATOM 1054 N N     . LEU A 1 254 ? 135.456 120.020 90.104  1.00 80.60  ? 254 LEU A N     1 
ATOM 1055 C CA    . LEU A 1 254 ? 135.234 120.182 91.532  1.00 80.60  ? 254 LEU A CA    1 
ATOM 1056 C C     . LEU A 1 254 ? 136.581 120.248 92.252  1.00 80.60  ? 254 LEU A C     1 
ATOM 1057 O O     . LEU A 1 254 ? 137.635 120.406 91.630  1.00 80.60  ? 254 LEU A O     1 
ATOM 1058 C CB    . LEU A 1 254 ? 134.361 119.049 92.060  1.00 80.60  ? 254 LEU A CB    1 
ATOM 1059 C CG    . LEU A 1 254 ? 133.128 118.722 91.220  1.00 80.60  ? 254 LEU A CG    1 
ATOM 1060 C CD1   . LEU A 1 254 ? 132.363 117.564 91.834  1.00 80.60  ? 254 LEU A CD1   1 
ATOM 1061 C CD2   . LEU A 1 254 ? 132.236 119.946 91.081  1.00 80.60  ? 254 LEU A CD2   1 
ATOM 1062 N N     . SER A 1 255 ? 136.560 120.129 93.578  1.00 87.27  ? 255 SER A N     1 
ATOM 1063 C CA    . SER A 1 255 ? 137.771 120.161 94.385  1.00 87.27  ? 255 SER A CA    1 
ATOM 1064 C C     . SER A 1 255 ? 137.800 118.955 95.310  1.00 87.27  ? 255 SER A C     1 
ATOM 1065 O O     . SER A 1 255 ? 136.767 118.550 95.849  1.00 87.27  ? 255 SER A O     1 
ATOM 1066 C CB    . SER A 1 255 ? 137.861 121.452 95.209  1.00 87.27  ? 255 SER A CB    1 
ATOM 1067 O OG    . SER A 1 255 ? 136.814 121.523 96.159  1.00 87.27  ? 255 SER A OG    1 
ATOM 1068 N N     . THR A 1 256 ? 138.991 118.382 95.490  1.00 86.79  ? 256 THR A N     1 
ATOM 1069 C CA    . THR A 1 256 ? 139.196 117.222 96.359  1.00 86.79  ? 256 THR A CA    1 
ATOM 1070 C C     . THR A 1 256 ? 140.340 117.552 97.312  1.00 86.79  ? 256 THR A C     1 
ATOM 1071 O O     . THR A 1 256 ? 141.498 117.221 97.048  1.00 86.79  ? 256 THR A O     1 
ATOM 1072 C CB    . THR A 1 256 ? 139.488 115.962 95.549  1.00 86.79  ? 256 THR A CB    1 
ATOM 1073 O OG1   . THR A 1 256 ? 140.637 116.180 94.721  1.00 86.79  ? 256 THR A OG1   1 
ATOM 1074 C CG2   . THR A 1 256 ? 138.297 115.598 94.675  1.00 86.79  ? 256 THR A CG2   1 
ATOM 1075 N N     . LYS A 1 257 ? 140.006 118.206 98.427  1.00 88.95  ? 257 LYS A N     1 
ATOM 1076 C CA    . LYS A 1 257 ? 140.975 118.517 99.471  1.00 88.95  ? 257 LYS A CA    1 
ATOM 1077 C C     . LYS A 1 257 ? 140.511 117.997 100.827 1.00 88.95  ? 257 LYS A C     1 
ATOM 1078 O O     . LYS A 1 257 ? 140.953 118.504 101.863 1.00 88.95  ? 257 LYS A O     1 
ATOM 1079 C CB    . LYS A 1 257 ? 141.235 120.025 99.539  1.00 88.95  ? 257 LYS A CB    1 
ATOM 1080 C CG    . LYS A 1 257 ? 142.647 120.399 99.964  1.00 88.95  ? 257 LYS A CG    1 
ATOM 1081 C CD    . LYS A 1 257 ? 143.665 120.004 98.907  1.00 88.95  ? 257 LYS A CD    1 
ATOM 1082 C CE    . LYS A 1 257 ? 145.064 120.462 99.289  1.00 88.95  ? 257 LYS A CE    1 
ATOM 1083 N NZ    . LYS A 1 257 ? 146.085 119.997 98.311  1.00 88.95  ? 257 LYS A NZ    1 
ATOM 1084 N N     . ASN A 1 258 ? 139.628 116.998 100.832 1.00 85.07  ? 258 ASN A N     1 
ATOM 1085 C CA    . ASN A 1 258 ? 139.033 116.459 102.054 1.00 85.07  ? 258 ASN A CA    1 
ATOM 1086 C C     . ASN A 1 258 ? 138.322 117.554 102.847 1.00 85.07  ? 258 ASN A C     1 
ATOM 1087 O O     . ASN A 1 258 ? 138.592 117.778 104.028 1.00 85.07  ? 258 ASN A O     1 
ATOM 1088 C CB    . ASN A 1 258 ? 140.081 115.745 102.911 1.00 85.07  ? 258 ASN A CB    1 
ATOM 1089 C CG    . ASN A 1 258 ? 139.460 114.810 103.927 1.00 85.07  ? 258 ASN A CG    1 
ATOM 1090 O OD1   . ASN A 1 258 ? 138.265 114.883 104.210 1.00 85.07  ? 258 ASN A OD1   1 
ATOM 1091 N ND2   . ASN A 1 258 ? 140.268 113.913 104.470 1.00 85.07  ? 258 ASN A ND2   1 
ATOM 1092 N N     . LYS A 1 259 ? 137.412 118.251 102.176 1.00 79.90  ? 259 LYS A N     1 
ATOM 1093 C CA    . LYS A 1 259 ? 136.589 119.254 102.827 1.00 79.90  ? 259 LYS A CA    1 
ATOM 1094 C C     . LYS A 1 259 ? 135.295 118.624 103.338 1.00 79.90  ? 259 LYS A C     1 
ATOM 1095 O O     . LYS A 1 259 ? 134.965 117.475 103.032 1.00 79.90  ? 259 LYS A O     1 
ATOM 1096 C CB    . LYS A 1 259 ? 136.291 120.404 101.868 1.00 79.90  ? 259 LYS A CB    1 
ATOM 1097 C CG    . LYS A 1 259 ? 135.520 119.991 100.625 1.00 79.90  ? 259 LYS A CG    1 
ATOM 1098 C CD    . LYS A 1 259 ? 135.387 121.148 99.650  1.00 79.90  ? 259 LYS A CD    1 
ATOM 1099 C CE    . LYS A 1 259 ? 134.348 122.148 100.115 1.00 79.90  ? 259 LYS A CE    1 
ATOM 1100 N NZ    . LYS A 1 259 ? 134.156 123.235 99.119  1.00 79.90  ? 259 LYS A NZ    1 
ATOM 1101 N N     . ARG A 1 260 ? 134.560 119.393 104.136 1.00 73.07  ? 260 ARG A N     1 
ATOM 1102 C CA    . ARG A 1 260 ? 133.312 118.902 104.705 1.00 73.07  ? 260 ARG A CA    1 
ATOM 1103 C C     . ARG A 1 260 ? 132.286 118.646 103.610 1.00 73.07  ? 260 ARG A C     1 
ATOM 1104 O O     . ARG A 1 260 ? 132.163 119.421 102.658 1.00 73.07  ? 260 ARG A O     1 
ATOM 1105 C CB    . ARG A 1 260 ? 132.758 119.904 105.716 1.00 73.07  ? 260 ARG A CB    1 
ATOM 1106 C CG    . ARG A 1 260 ? 131.494 119.435 106.410 1.00 73.07  ? 260 ARG A CG    1 
ATOM 1107 C CD    . ARG A 1 260 ? 130.751 120.590 107.049 1.00 73.07  ? 260 ARG A CD    1 
ATOM 1108 N NE    . ARG A 1 260 ? 129.346 120.267 107.261 1.00 73.07  ? 260 ARG A NE    1 
ATOM 1109 C CZ    . ARG A 1 260 ? 128.421 121.146 107.620 1.00 73.07  ? 260 ARG A CZ    1 
ATOM 1110 N NH1   . ARG A 1 260 ? 128.719 122.418 107.828 1.00 73.07  ? 260 ARG A NH1   1 
ATOM 1111 N NH2   . ARG A 1 260 ? 127.165 120.738 107.771 1.00 73.07  ? 260 ARG A NH2   1 
ATOM 1112 N N     . ILE A 1 261 ? 131.546 117.551 103.747 1.00 78.31  ? 261 ILE A N     1 
ATOM 1113 C CA    . ILE A 1 261 ? 130.519 117.180 102.782 1.00 78.31  ? 261 ILE A CA    1 
ATOM 1114 C C     . ILE A 1 261 ? 129.152 117.532 103.358 1.00 78.31  ? 261 ILE A C     1 
ATOM 1115 O O     . ILE A 1 261 ? 128.697 116.924 104.335 1.00 78.31  ? 261 ILE A O     1 
ATOM 1116 C CB    . ILE A 1 261 ? 130.614 115.693 102.400 1.00 78.31  ? 261 ILE A CB    1 
ATOM 1117 C CG1   . ILE A 1 261 ? 129.407 115.285 101.553 1.00 78.31  ? 261 ILE A CG1   1 
ATOM 1118 C CG2   . ILE A 1 261 ? 130.788 114.804 103.634 1.00 78.31  ? 261 ILE A CG2   1 
ATOM 1119 C CD1   . ILE A 1 261 ? 129.614 114.011 100.767 1.00 78.31  ? 261 ILE A CD1   1 
ATOM 1120 N N     . ARG A 1 262 ? 128.467 118.479 102.723 1.00 77.89  ? 262 ARG A N     1 
ATOM 1121 C CA    . ARG A 1 262 ? 127.112 118.812 103.151 1.00 77.89  ? 262 ARG A CA    1 
ATOM 1122 C C     . ARG A 1 262 ? 126.129 117.884 102.450 1.00 77.89  ? 262 ARG A C     1 
ATOM 1123 O O     . ARG A 1 262 ? 126.166 117.749 101.228 1.00 77.89  ? 262 ARG A O     1 
ATOM 1124 C CB    . ARG A 1 262 ? 126.777 120.269 102.832 1.00 77.89  ? 262 ARG A CB    1 
ATOM 1125 C CG    . ARG A 1 262 ? 127.659 121.285 103.538 1.00 77.89  ? 262 ARG A CG    1 
ATOM 1126 C CD    . ARG A 1 262 ? 127.113 122.696 103.368 1.00 77.89  ? 262 ARG A CD    1 
ATOM 1127 N NE    . ARG A 1 262 ? 126.991 123.085 101.964 1.00 77.89  ? 262 ARG A NE    1 
ATOM 1128 C CZ    . ARG A 1 262 ? 127.912 123.770 101.292 1.00 77.89  ? 262 ARG A CZ    1 
ATOM 1129 N NH1   . ARG A 1 262 ? 129.031 124.151 101.893 1.00 77.89  ? 262 ARG A NH1   1 
ATOM 1130 N NH2   . ARG A 1 262 ? 127.712 124.079 100.018 1.00 77.89  ? 262 ARG A NH2   1 
ATOM 1131 N N     . LYS A 1 263 ? 125.252 117.241 103.214 1.00 74.77  ? 263 LYS A N     1 
ATOM 1132 C CA    . LYS A 1 263 ? 124.257 116.336 102.640 1.00 74.77  ? 263 LYS A CA    1 
ATOM 1133 C C     . LYS A 1 263 ? 123.227 117.125 101.832 1.00 74.77  ? 263 LYS A C     1 
ATOM 1134 O O     . LYS A 1 263 ? 122.990 118.293 102.110 1.00 74.77  ? 263 LYS A O     1 
ATOM 1135 C CB    . LYS A 1 263 ? 123.575 115.544 103.757 1.00 74.77  ? 263 LYS A CB    1 
ATOM 1136 C CG    . LYS A 1 263 ? 122.548 114.529 103.287 1.00 74.77  ? 263 LYS A CG    1 
ATOM 1137 C CD    . LYS A 1 263 ? 123.111 113.126 103.176 1.00 74.77  ? 263 LYS A CD    1 
ATOM 1138 C CE    . LYS A 1 263 ? 122.020 112.159 102.746 1.00 74.77  ? 263 LYS A CE    1 
ATOM 1139 N NZ    . LYS A 1 263 ? 122.443 110.735 102.841 1.00 74.77  ? 263 LYS A NZ    1 
ATOM 1140 N N     . TRP A 1 264 ? 122.640 116.506 100.813 1.00 68.81  ? 264 TRP A N     1 
ATOM 1141 C CA    . TRP A 1 264 ? 121.668 117.201 99.971  1.00 68.81  ? 264 TRP A CA    1 
ATOM 1142 C C     . TRP A 1 264 ? 120.576 117.955 100.753 1.00 68.81  ? 264 TRP A C     1 
ATOM 1143 O O     . TRP A 1 264 ? 120.146 119.025 100.323 1.00 68.81  ? 264 TRP A O     1 
ATOM 1144 C CB    . TRP A 1 264 ? 121.046 116.251 98.935  1.00 68.81  ? 264 TRP A CB    1 
ATOM 1145 C CG    . TRP A 1 264 ? 120.126 115.218 99.510  1.00 68.81  ? 264 TRP A CG    1 
ATOM 1146 C CD1   . TRP A 1 264 ? 120.474 113.996 100.003 1.00 68.81  ? 264 TRP A CD1   1 
ATOM 1147 C CD2   . TRP A 1 264 ? 118.702 115.312 99.639  1.00 68.81  ? 264 TRP A CD2   1 
ATOM 1148 N NE1   . TRP A 1 264 ? 119.357 113.326 100.440 1.00 68.81  ? 264 TRP A NE1   1 
ATOM 1149 C CE2   . TRP A 1 264 ? 118.256 114.114 100.228 1.00 68.81  ? 264 TRP A CE2   1 
ATOM 1150 C CE3   . TRP A 1 264 ? 117.763 116.298 99.320  1.00 68.81  ? 264 TRP A CE3   1 
ATOM 1151 C CZ2   . TRP A 1 264 ? 116.913 113.873 100.502 1.00 68.81  ? 264 TRP A CZ2   1 
ATOM 1152 C CZ3   . TRP A 1 264 ? 116.431 116.057 99.594  1.00 68.81  ? 264 TRP A CZ3   1 
ATOM 1153 C CH2   . TRP A 1 264 ? 116.018 114.854 100.178 1.00 68.81  ? 264 TRP A CH2   1 
ATOM 1154 N N     . TYR A 1 265 ? 120.123 117.412 101.884 1.00 73.31  ? 265 TYR A N     1 
ATOM 1155 C CA    . TYR A 1 265 ? 119.056 118.071 102.632 1.00 73.31  ? 265 TYR A CA    1 
ATOM 1156 C C     . TYR A 1 265 ? 119.554 119.221 103.497 1.00 73.31  ? 265 TYR A C     1 
ATOM 1157 O O     . TYR A 1 265 ? 118.732 119.894 104.127 1.00 73.31  ? 265 TYR A O     1 
ATOM 1158 C CB    . TYR A 1 265 ? 118.285 117.064 103.499 1.00 73.31  ? 265 TYR A CB    1 
ATOM 1159 C CG    . TYR A 1 265 ? 118.963 116.641 104.786 1.00 73.31  ? 265 TYR A CG    1 
ATOM 1160 C CD1   . TYR A 1 265 ? 118.879 117.419 105.937 1.00 73.31  ? 265 TYR A CD1   1 
ATOM 1161 C CD2   . TYR A 1 265 ? 119.665 115.453 104.858 1.00 73.31  ? 265 TYR A CD2   1 
ATOM 1162 C CE1   . TYR A 1 265 ? 119.496 117.034 107.111 1.00 73.31  ? 265 TYR A CE1   1 
ATOM 1163 C CE2   . TYR A 1 265 ? 120.281 115.056 106.029 1.00 73.31  ? 265 TYR A CE2   1 
ATOM 1164 C CZ    . TYR A 1 265 ? 120.193 115.846 107.152 1.00 73.31  ? 265 TYR A CZ    1 
ATOM 1165 O OH    . TYR A 1 265 ? 120.807 115.446 108.317 1.00 73.31  ? 265 TYR A OH    1 
ATOM 1166 N N     . ALA A 1 266 ? 120.863 119.457 103.554 1.00 72.74  ? 266 ALA A N     1 
ATOM 1167 C CA    . ALA A 1 266 ? 121.403 120.536 104.371 1.00 72.74  ? 266 ALA A CA    1 
ATOM 1168 C C     . ALA A 1 266 ? 120.883 121.878 103.873 1.00 72.74  ? 266 ALA A C     1 
ATOM 1169 O O     . ALA A 1 266 ? 121.228 122.314 102.770 1.00 72.74  ? 266 ALA A O     1 
ATOM 1170 C CB    . ALA A 1 266 ? 122.928 120.507 104.340 1.00 72.74  ? 266 ALA A CB    1 
ATOM 1171 N N     . ARG A 1 267 ? 120.060 122.539 104.690 1.00 78.29  ? 267 ARG A N     1 
ATOM 1172 C CA    . ARG A 1 267 ? 119.455 123.799 104.273 1.00 78.29  ? 267 ARG A CA    1 
ATOM 1173 C C     . ARG A 1 267 ? 120.474 124.923 104.153 1.00 78.29  ? 267 ARG A C     1 
ATOM 1174 O O     . ARG A 1 267 ? 120.144 125.982 103.608 1.00 78.29  ? 267 ARG A O     1 
ATOM 1175 C CB    . ARG A 1 267 ? 118.344 124.207 105.242 1.00 78.29  ? 267 ARG A CB    1 
ATOM 1176 C CG    . ARG A 1 267 ? 118.818 124.542 106.637 1.00 78.29  ? 267 ARG A CG    1 
ATOM 1177 C CD    . ARG A 1 267 ? 117.743 125.269 107.429 1.00 78.29  ? 267 ARG A CD    1 
ATOM 1178 N NE    . ARG A 1 267 ? 117.052 126.271 106.627 1.00 78.29  ? 267 ARG A NE    1 
ATOM 1179 C CZ    . ARG A 1 267 ? 117.447 127.529 106.492 1.00 78.29  ? 267 ARG A CZ    1 
ATOM 1180 N NH1   . ARG A 1 267 ? 118.533 127.982 107.097 1.00 78.29  ? 267 ARG A NH1   1 
ATOM 1181 N NH2   . ARG A 1 267 ? 116.735 128.355 105.730 1.00 78.29  ? 267 ARG A NH2   1 
ATOM 1182 N N     . ALA A 1 268 ? 121.696 124.724 104.648 1.00 78.45  ? 268 ALA A N     1 
ATOM 1183 C CA    . ALA A 1 268 ? 122.759 125.686 104.398 1.00 78.45  ? 268 ALA A CA    1 
ATOM 1184 C C     . ALA A 1 268 ? 123.077 125.814 102.918 1.00 78.45  ? 268 ALA A C     1 
ATOM 1185 O O     . ALA A 1 268 ? 123.661 126.824 102.509 1.00 78.45  ? 268 ALA A O     1 
ATOM 1186 C CB    . ALA A 1 268 ? 124.021 125.290 105.166 1.00 78.45  ? 268 ALA A CB    1 
ATOM 1187 N N     . ASN A 1 269 ? 122.707 124.821 102.113 1.00 82.63  ? 269 ASN A N     1 
ATOM 1188 C CA    . ASN A 1 269 ? 122.896 124.849 100.671 1.00 82.63  ? 269 ASN A CA    1 
ATOM 1189 C C     . ASN A 1 269 ? 121.665 125.338 99.919  1.00 82.63  ? 269 ASN A C     1 
ATOM 1190 O O     . ASN A 1 269 ? 121.718 125.461 98.691  1.00 82.63  ? 269 ASN A O     1 
ATOM 1191 C CB    . ASN A 1 269 ? 123.275 123.448 100.172 1.00 82.63  ? 269 ASN A CB    1 
ATOM 1192 C CG    . ASN A 1 269 ? 124.260 123.482 99.024  1.00 82.63  ? 269 ASN A CG    1 
ATOM 1193 O OD1   . ASN A 1 269 ? 124.670 124.549 98.570  1.00 82.63  ? 269 ASN A OD1   1 
ATOM 1194 N ND2   . ASN A 1 269 ? 124.653 122.305 98.553  1.00 82.63  ? 269 ASN A ND2   1 
ATOM 1195 N N     . TRP A 1 270 ? 120.565 125.616 100.621 1.00 82.42  ? 270 TRP A N     1 
ATOM 1196 C CA    . TRP A 1 270 ? 119.309 126.021 99.998  1.00 82.42  ? 270 TRP A CA    1 
ATOM 1197 C C     . TRP A 1 270 ? 118.896 127.429 100.412 1.00 82.42  ? 270 TRP A C     1 
ATOM 1198 O O     . TRP A 1 270 ? 117.725 127.794 100.272 1.00 82.42  ? 270 TRP A O     1 
ATOM 1199 C CB    . TRP A 1 270 ? 118.198 125.025 100.345 1.00 82.42  ? 270 TRP A CB    1 
ATOM 1200 C CG    . TRP A 1 270 ? 118.401 123.643 99.796  1.00 82.42  ? 270 TRP A CG    1 
ATOM 1201 C CD1   . TRP A 1 270 ? 119.426 122.791 100.082 1.00 82.42  ? 270 TRP A CD1   1 
ATOM 1202 C CD2   . TRP A 1 270 ? 117.541 122.943 98.887  1.00 82.42  ? 270 TRP A CD2   1 
ATOM 1203 N NE1   . TRP A 1 270 ? 119.266 121.611 99.397  1.00 82.42  ? 270 TRP A NE1   1 
ATOM 1204 C CE2   . TRP A 1 270 ? 118.116 121.679 98.658  1.00 82.42  ? 270 TRP A CE2   1 
ATOM 1205 C CE3   . TRP A 1 270 ? 116.345 123.266 98.240  1.00 82.42  ? 270 TRP A CE3   1 
ATOM 1206 C CZ2   . TRP A 1 270 ? 117.536 120.738 97.810  1.00 82.42  ? 270 TRP A CZ2   1 
ATOM 1207 C CZ3   . TRP A 1 270 ? 115.773 122.330 97.399  1.00 82.42  ? 270 TRP A CZ3   1 
ATOM 1208 C CH2   . TRP A 1 270 ? 116.367 121.082 97.192  1.00 82.42  ? 270 TRP A CH2   1 
ATOM 1209 N N     . ARG A 1 271 ? 119.834 128.225 100.924 1.00 93.94  ? 271 ARG A N     1 
ATOM 1210 C CA    . ARG A 1 271 ? 119.507 129.552 101.428 1.00 93.94  ? 271 ARG A CA    1 
ATOM 1211 C C     . ARG A 1 271 ? 118.995 130.451 100.309 1.00 93.94  ? 271 ARG A C     1 
ATOM 1212 O O     . ARG A 1 271 ? 119.440 130.361 99.161  1.00 93.94  ? 271 ARG A O     1 
ATOM 1213 C CB    . ARG A 1 271 ? 120.734 130.179 102.088 1.00 93.94  ? 271 ARG A CB    1 
ATOM 1214 C CG    . ARG A 1 271 ? 122.009 130.018 101.283 1.00 93.94  ? 271 ARG A CG    1 
ATOM 1215 C CD    . ARG A 1 271 ? 123.205 130.565 102.034 1.00 93.94  ? 271 ARG A CD    1 
ATOM 1216 N NE    . ARG A 1 271 ? 123.077 131.995 102.284 1.00 93.94  ? 271 ARG A NE    1 
ATOM 1217 C CZ    . ARG A 1 271 ? 123.391 132.938 101.406 1.00 93.94  ? 271 ARG A CZ    1 
ATOM 1218 N NH1   . ARG A 1 271 ? 123.860 132.638 100.206 1.00 93.94  ? 271 ARG A NH1   1 
ATOM 1219 N NH2   . ARG A 1 271 ? 123.229 134.215 101.742 1.00 93.94  ? 271 ARG A NH2   1 
ATOM 1220 N N     . ARG A 1 272 ? 118.052 131.323 100.653 1.00 103.43 ? 272 ARG A N     1 
ATOM 1221 C CA    . ARG A 1 272 ? 117.377 132.166 99.677  1.00 103.43 ? 272 ARG A CA    1 
ATOM 1222 C C     . ARG A 1 272 ? 118.205 133.409 99.370  1.00 103.43 ? 272 ARG A C     1 
ATOM 1223 O O     . ARG A 1 272 ? 118.785 134.019 100.273 1.00 103.43 ? 272 ARG A O     1 
ATOM 1224 C CB    . ARG A 1 272 ? 115.987 132.561 100.182 1.00 103.43 ? 272 ARG A CB    1 
ATOM 1225 C CG    . ARG A 1 272 ? 115.985 133.368 101.472 1.00 103.43 ? 272 ARG A CG    1 
ATOM 1226 C CD    . ARG A 1 272 ? 114.570 133.672 101.941 1.00 103.43 ? 272 ARG A CD    1 
ATOM 1227 N NE    . ARG A 1 272 ? 113.855 132.470 102.352 1.00 103.43 ? 272 ARG A NE    1 
ATOM 1228 C CZ    . ARG A 1 272 ? 112.836 131.939 101.688 1.00 103.43 ? 272 ARG A CZ    1 
ATOM 1229 N NH1   . ARG A 1 272 ? 112.383 132.481 100.570 1.00 103.43 ? 272 ARG A NH1   1 
ATOM 1230 N NH2   . ARG A 1 272 ? 112.258 130.838 102.159 1.00 103.43 ? 272 ARG A NH2   1 
ATOM 1231 N N     . LYS A 1 273 ? 118.260 133.767 98.091  1.00 101.78 ? 273 LYS A N     1 
ATOM 1232 C CA    . LYS A 1 273 ? 118.906 134.983 97.618  1.00 101.78 ? 273 LYS A CA    1 
ATOM 1233 C C     . LYS A 1 273 ? 118.265 135.366 96.292  1.00 101.78 ? 273 LYS A C     1 
ATOM 1234 O O     . LYS A 1 273 ? 117.642 134.521 95.638  1.00 101.78 ? 273 LYS A O     1 
ATOM 1235 C CB    . LYS A 1 273 ? 120.423 134.784 97.449  1.00 101.78 ? 273 LYS A CB    1 
ATOM 1236 C CG    . LYS A 1 273 ? 121.263 135.137 98.671  1.00 101.78 ? 273 LYS A CG    1 
ATOM 1237 C CD    . LYS A 1 273 ? 121.214 136.624 98.980  1.00 101.78 ? 273 LYS A CD    1 
ATOM 1238 C CE    . LYS A 1 273 ? 122.102 136.973 100.163 1.00 101.78 ? 273 LYS A CE    1 
ATOM 1239 N NZ    . LYS A 1 273 ? 122.076 138.431 100.464 1.00 101.78 ? 273 LYS A NZ    1 
ATOM 1240 N N     . PRO A 1 274 ? 118.377 136.632 95.878  1.00 104.31 ? 274 PRO A N     1 
ATOM 1241 C CA    . PRO A 1 274 ? 117.813 137.020 94.573  1.00 104.31 ? 274 PRO A CA    1 
ATOM 1242 C C     . PRO A 1 274 ? 118.352 136.210 93.406  1.00 104.31 ? 274 PRO A C     1 
ATOM 1243 O O     . PRO A 1 274 ? 117.597 135.911 92.471  1.00 104.31 ? 274 PRO A O     1 
ATOM 1244 C CB    . PRO A 1 274 ? 118.198 138.501 94.460  1.00 104.31 ? 274 PRO A CB    1 
ATOM 1245 C CG    . PRO A 1 274 ? 118.294 138.964 95.869  1.00 104.31 ? 274 PRO A CG    1 
ATOM 1246 C CD    . PRO A 1 274 ? 118.846 137.800 96.644  1.00 104.31 ? 274 PRO A CD    1 
ATOM 1247 N N     . GLY A 1 275 ? 119.635 135.843 93.427  1.00 98.34  ? 275 GLY A N     1 
ATOM 1248 C CA    . GLY A 1 275 ? 120.189 135.027 92.361  1.00 98.34  ? 275 GLY A CA    1 
ATOM 1249 C C     . GLY A 1 275 ? 119.869 133.552 92.477  1.00 98.34  ? 275 GLY A C     1 
ATOM 1250 O O     . GLY A 1 275 ? 119.882 132.844 91.464  1.00 98.34  ? 275 GLY A O     1 
ATOM 1251 N N     . ARG A 1 276 ? 119.544 133.105 93.688  1.00 93.61  ? 276 ARG A N     1 
ATOM 1252 C CA    . ARG A 1 276 ? 119.251 131.694 93.922  1.00 93.61  ? 276 ARG A CA    1 
ATOM 1253 C C     . ARG A 1 276 ? 117.834 131.280 93.556  1.00 93.61  ? 276 ARG A C     1 
ATOM 1254 O O     . ARG A 1 276 ? 116.905 132.081 93.657  1.00 93.61  ? 276 ARG A O     1 
ATOM 1255 C CB    . ARG A 1 276 ? 119.533 131.332 95.383  1.00 93.61  ? 276 ARG A CB    1 
ATOM 1256 C CG    . ARG A 1 276 ? 121.008 131.338 95.750  1.00 93.61  ? 276 ARG A CG    1 
ATOM 1257 C CD    . ARG A 1 276 ? 121.455 129.969 96.233  1.00 93.61  ? 276 ARG A CD    1 
ATOM 1258 N NE    . ARG A 1 276 ? 122.521 130.053 97.226  1.00 93.61  ? 276 ARG A NE    1 
ATOM 1259 C CZ    . ARG A 1 276 ? 123.165 128.998 97.716  1.00 93.61  ? 276 ARG A CZ    1 
ATOM 1260 N NH1   . ARG A 1 276 ? 122.850 127.779 97.303  1.00 93.61  ? 276 ARG A NH1   1 
ATOM 1261 N NH2   . ARG A 1 276 ? 124.122 129.161 98.617  1.00 93.61  ? 276 ARG A NH2   1 
ATOM 1262 N N     . LYS A 1 277 ? 117.666 130.032 93.135  1.00 95.03  ? 277 LYS A N     1 
ATOM 1263 C CA    . LYS A 1 277 ? 116.357 129.502 92.766  1.00 95.03  ? 277 LYS A CA    1 
ATOM 1264 C C     . LYS A 1 277 ? 116.126 128.258 93.612  1.00 95.03  ? 277 LYS A C     1 
ATOM 1265 O O     . LYS A 1 277 ? 117.003 127.393 93.689  1.00 95.03  ? 277 LYS A O     1 
ATOM 1266 C CB    . LYS A 1 277 ? 116.281 129.174 91.275  1.00 95.03  ? 277 LYS A CB    1 
ATOM 1267 C CG    . LYS A 1 277 ? 116.580 130.350 90.356  1.00 95.03  ? 277 LYS A CG    1 
ATOM 1268 C CD    . LYS A 1 277 ? 115.390 131.294 90.245  1.00 95.03  ? 277 LYS A CD    1 
ATOM 1269 C CE    . LYS A 1 277 ? 114.110 130.551 89.895  1.00 95.03  ? 277 LYS A CE    1 
ATOM 1270 N NZ    . LYS A 1 277 ? 114.291 129.629 88.739  1.00 95.03  ? 277 LYS A NZ    1 
ATOM 1271 N N     . SER A 1 278 ? 114.966 128.172 94.256  1.00 104.84 ? 278 SER A N     1 
ATOM 1272 C CA    . SER A 1 278 ? 114.675 127.038 95.124  1.00 104.84 ? 278 SER A CA    1 
ATOM 1273 C C     . SER A 1 278 ? 113.179 126.985 95.397  1.00 104.84 ? 278 SER A C     1 
ATOM 1274 O O     . SER A 1 278 ? 112.458 127.973 95.234  1.00 104.84 ? 278 SER A O     1 
ATOM 1275 C CB    . SER A 1 278 ? 115.463 127.125 96.435  1.00 104.84 ? 278 SER A CB    1 
ATOM 1276 O OG    . SER A 1 278 ? 115.120 128.294 97.159  1.00 104.84 ? 278 SER A OG    1 
ATOM 1277 N N     . VAL A 1 279 ? 112.724 125.807 95.819  1.00 105.99 ? 279 VAL A N     1 
ATOM 1278 C CA    . VAL A 1 279 ? 111.354 125.612 96.283  1.00 105.99 ? 279 VAL A CA    1 
ATOM 1279 C C     . VAL A 1 279 ? 111.386 124.952 97.658  1.00 105.99 ? 279 VAL A C     1 
ATOM 1280 O O     . VAL A 1 279 ? 111.418 123.722 97.782  1.00 105.99 ? 279 VAL A O     1 
ATOM 1281 C CB    . VAL A 1 279 ? 110.526 124.810 95.258  1.00 105.99 ? 279 VAL A CB    1 
ATOM 1282 C CG1   . VAL A 1 279 ? 110.287 125.649 94.016  1.00 105.99 ? 279 VAL A CG1   1 
ATOM 1283 C CG2   . VAL A 1 279 ? 111.251 123.532 94.844  1.00 105.99 ? 279 VAL A CG2   1 
ATOM 1284 N N     . LEU A 1 280 ? 111.377 125.773 98.705  1.00 101.77 ? 280 LEU A N     1 
ATOM 1285 C CA    . LEU A 1 280 ? 111.554 125.261 100.057 1.00 101.77 ? 280 LEU A CA    1 
ATOM 1286 C C     . LEU A 1 280 ? 110.275 124.607 100.562 1.00 101.77 ? 280 LEU A C     1 
ATOM 1287 O O     . LEU A 1 280 ? 109.187 125.182 100.468 1.00 101.77 ? 280 LEU A O     1 
ATOM 1288 C CB    . LEU A 1 280 ? 111.977 126.391 100.994 1.00 101.77 ? 280 LEU A CB    1 
ATOM 1289 C CG    . LEU A 1 280 ? 111.966 126.079 102.492 1.00 101.77 ? 280 LEU A CG    1 
ATOM 1290 C CD1   . LEU A 1 280 ? 112.935 124.952 102.814 1.00 101.77 ? 280 LEU A CD1   1 
ATOM 1291 C CD2   . LEU A 1 280 ? 112.296 127.324 103.302 1.00 101.77 ? 280 LEU A CD2   1 
ATOM 1292 N N     . ASP A 1 281 ? 110.413 123.397 101.099 1.00 98.82  ? 281 ASP A N     1 
ATOM 1293 C CA    . ASP A 1 281 ? 109.306 122.682 101.722 1.00 98.82  ? 281 ASP A CA    1 
ATOM 1294 C C     . ASP A 1 281 ? 109.785 122.147 103.060 1.00 98.82  ? 281 ASP A C     1 
ATOM 1295 O O     . ASP A 1 281 ? 110.870 121.563 103.141 1.00 98.82  ? 281 ASP A O     1 
ATOM 1296 C CB    . ASP A 1 281 ? 108.804 121.541 100.831 1.00 98.82  ? 281 ASP A CB    1 
ATOM 1297 C CG    . ASP A 1 281 ? 108.153 122.041 99.556  1.00 98.82  ? 281 ASP A CG    1 
ATOM 1298 O OD1   . ASP A 1 281 ? 107.355 122.999 99.631  1.00 98.82  ? 281 ASP A OD1   1 
ATOM 1299 O OD2   . ASP A 1 281 ? 108.438 121.476 98.479  1.00 98.82  ? 281 ASP A OD2   1 
ATOM 1300 N N     . GLU A 1 282 ? 108.981 122.346 104.107 1.00 93.83  ? 282 GLU A N     1 
ATOM 1301 C CA    . GLU A 1 282 ? 109.378 121.907 105.440 1.00 93.83  ? 282 GLU A CA    1 
ATOM 1302 C C     . GLU A 1 282 ? 109.424 120.391 105.563 1.00 93.83  ? 282 GLU A C     1 
ATOM 1303 O O     . GLU A 1 282 ? 110.034 119.873 106.505 1.00 93.83  ? 282 GLU A O     1 
ATOM 1304 C CB    . GLU A 1 282 ? 108.426 122.488 106.488 1.00 93.83  ? 282 GLU A CB    1 
ATOM 1305 C CG    . GLU A 1 282 ? 109.054 122.678 107.862 1.00 93.83  ? 282 GLU A CG    1 
ATOM 1306 C CD    . GLU A 1 282 ? 110.090 123.786 107.890 1.00 93.83  ? 282 GLU A CD    1 
ATOM 1307 O OE1   . GLU A 1 282 ? 110.085 124.637 106.975 1.00 93.83  ? 282 GLU A OE1   1 
ATOM 1308 O OE2   . GLU A 1 282 ? 110.913 123.805 108.829 1.00 93.83  ? 282 GLU A OE2   1 
ATOM 1309 N N     . ALA A 1 283 ? 108.795 119.668 104.639 1.00 88.46  ? 283 ALA A N     1 
ATOM 1310 C CA    . ALA A 1 283 ? 108.796 118.209 104.678 1.00 88.46  ? 283 ALA A CA    1 
ATOM 1311 C C     . ALA A 1 283 ? 109.955 117.626 103.874 1.00 88.46  ? 283 ALA A C     1 
ATOM 1312 O O     . ALA A 1 283 ? 110.703 116.781 104.374 1.00 88.46  ? 283 ALA A O     1 
ATOM 1313 C CB    . ALA A 1 283 ? 107.456 117.671 104.166 1.00 88.46  ? 283 ALA A CB    1 
ATOM 1314 N N     . LYS A 1 284 ? 110.113 118.067 102.626 1.00 85.89  ? 284 LYS A N     1 
ATOM 1315 C CA    . LYS A 1 284 ? 111.132 117.482 101.760 1.00 85.89  ? 284 LYS A CA    1 
ATOM 1316 C C     . LYS A 1 284 ? 112.533 117.720 102.308 1.00 85.89  ? 284 LYS A C     1 
ATOM 1317 O O     . LYS A 1 284 ? 113.391 116.831 102.245 1.00 85.89  ? 284 LYS A O     1 
ATOM 1318 C CB    . LYS A 1 284 ? 111.007 118.050 100.347 1.00 85.89  ? 284 LYS A CB    1 
ATOM 1319 C CG    . LYS A 1 284 ? 109.653 117.810 99.700  1.00 85.89  ? 284 LYS A CG    1 
ATOM 1320 C CD    . LYS A 1 284 ? 109.230 116.354 99.823  1.00 85.89  ? 284 LYS A CD    1 
ATOM 1321 C CE    . LYS A 1 284 ? 107.732 116.191 99.615  1.00 85.89  ? 284 LYS A CE    1 
ATOM 1322 N NZ    . LYS A 1 284 ? 106.941 117.014 100.571 1.00 85.89  ? 284 LYS A NZ    1 
ATOM 1323 N N     . LEU A 1 285 ? 112.784 118.908 102.854 1.00 77.51  ? 285 LEU A N     1 
ATOM 1324 C CA    . LEU A 1 285 ? 114.135 119.250 103.280 1.00 77.51  ? 285 LEU A CA    1 
ATOM 1325 C C     . LEU A 1 285 ? 114.380 118.897 104.743 1.00 77.51  ? 285 LEU A C     1 
ATOM 1326 O O     . LEU A 1 285 ? 115.406 118.294 105.072 1.00 77.51  ? 285 LEU A O     1 
ATOM 1327 C CB    . LEU A 1 285 ? 114.392 120.737 103.025 1.00 77.51  ? 285 LEU A CB    1 
ATOM 1328 C CG    . LEU A 1 285 ? 115.796 121.310 103.228 1.00 77.51  ? 285 LEU A CG    1 
ATOM 1329 C CD1   . LEU A 1 285 ? 116.002 122.527 102.346 1.00 77.51  ? 285 LEU A CD1   1 
ATOM 1330 C CD2   . LEU A 1 285 ? 116.021 121.687 104.681 1.00 77.51  ? 285 LEU A CD2   1 
ATOM 1331 N N     . LYS A 1 286 ? 113.458 119.256 105.634 1.00 83.53  ? 286 LYS A N     1 
ATOM 1332 C CA    . LYS A 1 286 ? 113.722 119.135 107.063 1.00 83.53  ? 286 LYS A CA    1 
ATOM 1333 C C     . LYS A 1 286 ? 113.366 117.760 107.617 1.00 83.53  ? 286 LYS A C     1 
ATOM 1334 O O     . LYS A 1 286 ? 114.064 117.255 108.503 1.00 83.53  ? 286 LYS A O     1 
ATOM 1335 C CB    . LYS A 1 286 ? 112.962 120.221 107.830 1.00 83.53  ? 286 LYS A CB    1 
ATOM 1336 C CG    . LYS A 1 286 ? 113.376 120.365 109.287 1.00 83.53  ? 286 LYS A CG    1 
ATOM 1337 C CD    . LYS A 1 286 ? 112.335 119.774 110.224 1.00 83.53  ? 286 LYS A CD    1 
ATOM 1338 C CE    . LYS A 1 286 ? 111.080 120.631 110.262 1.00 83.53  ? 286 LYS A CE    1 
ATOM 1339 N NZ    . LYS A 1 286 ? 110.052 120.073 111.184 1.00 83.53  ? 286 LYS A NZ    1 
ATOM 1340 N N     . GLU A 1 287 ? 112.291 117.142 107.123 1.00 80.14  ? 287 GLU A N     1 
ATOM 1341 C CA    . GLU A 1 287 ? 111.915 115.824 107.622 1.00 80.14  ? 287 GLU A CA    1 
ATOM 1342 C C     . GLU A 1 287 ? 112.936 114.762 107.229 1.00 80.14  ? 287 GLU A C     1 
ATOM 1343 O O     . GLU A 1 287 ? 113.006 113.705 107.867 1.00 80.14  ? 287 GLU A O     1 
ATOM 1344 C CB    . GLU A 1 287 ? 110.523 115.450 107.118 1.00 80.14  ? 287 GLU A CB    1 
ATOM 1345 C CG    . GLU A 1 287 ? 109.935 114.193 107.737 1.00 80.14  ? 287 GLU A CG    1 
ATOM 1346 C CD    . GLU A 1 287 ? 110.183 112.961 106.892 1.00 80.14  ? 287 GLU A CD    1 
ATOM 1347 O OE1   . GLU A 1 287 ? 109.791 112.964 105.707 1.00 80.14  ? 287 GLU A OE1   1 
ATOM 1348 O OE2   . GLU A 1 287 ? 110.769 111.989 107.412 1.00 80.14  ? 287 GLU A OE2   1 
ATOM 1349 N N     . ALA A 1 288 ? 113.742 115.025 106.198 1.00 75.38  ? 288 ALA A N     1 
ATOM 1350 C CA    . ALA A 1 288 ? 114.770 114.072 105.799 1.00 75.38  ? 288 ALA A CA    1 
ATOM 1351 C C     . ALA A 1 288 ? 115.871 113.935 106.840 1.00 75.38  ? 288 ALA A C     1 
ATOM 1352 O O     . ALA A 1 288 ? 116.617 112.951 106.809 1.00 75.38  ? 288 ALA A O     1 
ATOM 1353 C CB    . ALA A 1 288 ? 115.376 114.483 104.459 1.00 75.38  ? 288 ALA A CB    1 
ATOM 1354 N N     . ALA A 1 289 ? 115.992 114.897 107.757 1.00 75.65  ? 289 ALA A N     1 
ATOM 1355 C CA    . ALA A 1 289 ? 117.059 114.848 108.750 1.00 75.65  ? 289 ALA A CA    1 
ATOM 1356 C C     . ALA A 1 289 ? 116.840 113.723 109.751 1.00 75.65  ? 289 ALA A C     1 
ATOM 1357 O O     . ALA A 1 289 ? 117.775 112.982 110.076 1.00 75.65  ? 289 ALA A O     1 
ATOM 1358 C CB    . ALA A 1 289 ? 117.163 116.189 109.475 1.00 75.65  ? 289 ALA A CB    1 
ATOM 1359 N N     . LEU A 1 290 ? 115.612 113.579 110.250 1.00 77.30  ? 290 LEU A N     1 
ATOM 1360 C CA    . LEU A 1 290 ? 115.351 112.637 111.329 1.00 77.30  ? 290 LEU A CA    1 
ATOM 1361 C C     . LEU A 1 290 ? 115.473 111.188 110.881 1.00 77.30  ? 290 LEU A C     1 
ATOM 1362 O O     . LEU A 1 290 ? 115.464 110.290 111.731 1.00 77.30  ? 290 LEU A O     1 
ATOM 1363 C CB    . LEU A 1 290 ? 113.965 112.887 111.920 1.00 77.30  ? 290 LEU A CB    1 
ATOM 1364 C CG    . LEU A 1 290 ? 113.793 114.218 112.651 1.00 77.30  ? 290 LEU A CG    1 
ATOM 1365 C CD1   . LEU A 1 290 ? 113.112 115.240 111.757 1.00 77.30  ? 290 LEU A CD1   1 
ATOM 1366 C CD2   . LEU A 1 290 ? 113.007 114.019 113.937 1.00 77.30  ? 290 LEU A CD2   1 
ATOM 1367 N N     . LYS A 1 291 ? 115.579 110.936 109.575 1.00 77.24  ? 291 LYS A N     1 
ATOM 1368 C CA    . LYS A 1 291 ? 115.766 109.567 109.112 1.00 77.24  ? 291 LYS A CA    1 
ATOM 1369 C C     . LYS A 1 291 ? 117.103 109.014 109.585 1.00 77.24  ? 291 LYS A C     1 
ATOM 1370 O O     . LYS A 1 291 ? 117.150 108.034 110.338 1.00 77.24  ? 291 LYS A O     1 
ATOM 1371 C CB    . LYS A 1 291 ? 115.665 109.507 107.588 1.00 77.24  ? 291 LYS A CB    1 
ATOM 1372 C CG    . LYS A 1 291 ? 115.846 108.110 107.013 1.00 77.24  ? 291 LYS A CG    1 
ATOM 1373 C CD    . LYS A 1 291 ? 115.974 108.146 105.500 1.00 77.24  ? 291 LYS A CD    1 
ATOM 1374 C CE    . LYS A 1 291 ? 114.815 108.899 104.869 1.00 77.24  ? 291 LYS A CE    1 
ATOM 1375 N NZ    . LYS A 1 291 ? 113.512 108.230 105.136 1.00 77.24  ? 291 LYS A NZ    1 
ATOM 1376 N N     . GLU A 1 292 ? 118.200 109.627 109.155 1.00 73.92  ? 292 GLU A N     1 
ATOM 1377 C CA    . GLU A 1 292 ? 119.532 109.257 109.632 1.00 73.92  ? 292 GLU A CA    1 
ATOM 1378 C C     . GLU A 1 292 ? 120.061 110.289 110.631 1.00 73.92  ? 292 GLU A C     1 
ATOM 1379 O O     . GLU A 1 292 ? 121.025 111.018 110.395 1.00 73.92  ? 292 GLU A O     1 
ATOM 1380 C CB    . GLU A 1 292 ? 120.475 109.046 108.448 1.00 73.92  ? 292 GLU A CB    1 
ATOM 1381 C CG    . GLU A 1 292 ? 120.726 110.257 107.564 1.00 73.92  ? 292 GLU A CG    1 
ATOM 1382 C CD    . GLU A 1 292 ? 121.720 109.957 106.463 1.00 73.92  ? 292 GLU A CD    1 
ATOM 1383 O OE1   . GLU A 1 292 ? 122.046 108.769 106.261 1.00 73.92  ? 292 GLU A OE1   1 
ATOM 1384 O OE2   . GLU A 1 292 ? 122.181 110.908 105.804 1.00 73.92  ? 292 GLU A OE2   1 
ATOM 1385 N N     . ALA A 1 293 ? 119.401 110.333 111.784 1.00 69.83  ? 293 ALA A N     1 
ATOM 1386 C CA    . ALA A 1 293 ? 119.833 111.143 112.912 1.00 69.83  ? 293 ALA A CA    1 
ATOM 1387 C C     . ALA A 1 293 ? 120.459 110.238 113.963 1.00 69.83  ? 293 ALA A C     1 
ATOM 1388 O O     . ALA A 1 293 ? 120.251 109.021 113.958 1.00 69.83  ? 293 ALA A O     1 
ATOM 1389 C CB    . ALA A 1 293 ? 118.667 111.928 113.522 1.00 69.83  ? 293 ALA A CB    1 
ATOM 1390 N N     . ILE A 1 294 ? 121.229 110.834 114.862 1.00 67.98  ? 294 ILE A N     1 
ATOM 1391 C CA    . ILE A 1 294 ? 121.923 110.107 115.915 1.00 67.98  ? 294 ILE A CA    1 
ATOM 1392 C C     . ILE A 1 294 ? 121.377 110.575 117.257 1.00 67.98  ? 294 ILE A C     1 
ATOM 1393 O O     . ILE A 1 294 ? 121.843 111.567 117.819 1.00 67.98  ? 294 ILE A O     1 
ATOM 1394 C CB    . ILE A 1 294 ? 123.446 110.304 115.827 1.00 67.98  ? 294 ILE A CB    1 
ATOM 1395 C CG1   . ILE A 1 294 ? 123.950 109.804 114.474 1.00 67.98  ? 294 ILE A CG1   1 
ATOM 1396 C CG2   . ILE A 1 294 ? 124.146 109.549 116.945 1.00 67.98  ? 294 ILE A CG2   1 
ATOM 1397 C CD1   . ILE A 1 294 ? 125.395 110.117 114.203 1.00 67.98  ? 294 ILE A CD1   1 
ATOM 1398 N N     . PRO A 1 295 ? 120.377 109.886 117.799 1.00 63.33  ? 295 PRO A N     1 
ATOM 1399 C CA    . PRO A 1 295 ? 119.731 110.355 119.026 1.00 63.33  ? 295 PRO A CA    1 
ATOM 1400 C C     . PRO A 1 295 ? 120.493 109.953 120.278 1.00 63.33  ? 295 PRO A C     1 
ATOM 1401 O O     . PRO A 1 295 ? 121.021 108.844 120.385 1.00 63.33  ? 295 PRO A O     1 
ATOM 1402 C CB    . PRO A 1 295 ? 118.358 109.669 118.984 1.00 63.33  ? 295 PRO A CB    1 
ATOM 1403 C CG    . PRO A 1 295 ? 118.231 109.097 117.597 1.00 63.33  ? 295 PRO A CG    1 
ATOM 1404 C CD    . PRO A 1 295 ? 119.623 108.789 117.178 1.00 63.33  ? 295 PRO A CD    1 
ATOM 1405 N N     . ILE A 1 296 ? 120.536 110.879 121.232 1.00 65.40  ? 296 ILE A N     1 
ATOM 1406 C CA    . ILE A 1 296 ? 121.011 110.629 122.586 1.00 65.40  ? 296 ILE A CA    1 
ATOM 1407 C C     . ILE A 1 296 ? 120.004 111.246 123.547 1.00 65.40  ? 296 ILE A C     1 
ATOM 1408 O O     . ILE A 1 296 ? 119.344 112.238 123.224 1.00 65.40  ? 296 ILE A O     1 
ATOM 1409 C CB    . ILE A 1 296 ? 122.429 111.195 122.811 1.00 65.40  ? 296 ILE A CB    1 
ATOM 1410 C CG1   . ILE A 1 296 ? 122.459 112.696 122.532 1.00 65.40  ? 296 ILE A CG1   1 
ATOM 1411 C CG2   . ILE A 1 296 ? 123.440 110.477 121.936 1.00 65.40  ? 296 ILE A CG2   1 
ATOM 1412 C CD1   . ILE A 1 296 ? 123.796 113.336 122.829 1.00 65.40  ? 296 ILE A CD1   1 
ATOM 1413 N N     . ILE A 1 297 ? 119.879 110.654 124.734 1.00 65.81  ? 297 ILE A N     1 
ATOM 1414 C CA    . ILE A 1 297 ? 118.798 110.984 125.656 1.00 65.81  ? 297 ILE A CA    1 
ATOM 1415 C C     . ILE A 1 297 ? 119.367 111.504 126.968 1.00 65.81  ? 297 ILE A C     1 
ATOM 1416 O O     . ILE A 1 297 ? 120.322 110.941 127.513 1.00 65.81  ? 297 ILE A O     1 
ATOM 1417 C CB    . ILE A 1 297 ? 117.876 109.774 125.915 1.00 65.81  ? 297 ILE A CB    1 
ATOM 1418 C CG1   . ILE A 1 297 ? 118.698 108.519 126.196 1.00 65.81  ? 297 ILE A CG1   1 
ATOM 1419 C CG2   . ILE A 1 297 ? 116.949 109.553 124.737 1.00 65.81  ? 297 ILE A CG2   1 
ATOM 1420 C CD1   . ILE A 1 297 ? 117.882 107.370 126.741 1.00 65.81  ? 297 ILE A CD1   1 
ATOM 1421 N N     . VAL A 1 298 ? 118.776 112.588 127.464 1.00 63.91  ? 298 VAL A N     1 
ATOM 1422 C CA    . VAL A 1 298 ? 119.049 113.125 128.791 1.00 63.91  ? 298 VAL A CA    1 
ATOM 1423 C C     . VAL A 1 298 ? 117.752 113.052 129.582 1.00 63.91  ? 298 VAL A C     1 
ATOM 1424 O O     . VAL A 1 298 ? 116.742 113.642 129.180 1.00 63.91  ? 298 VAL A O     1 
ATOM 1425 C CB    . VAL A 1 298 ? 119.572 114.568 128.731 1.00 63.91  ? 298 VAL A CB    1 
ATOM 1426 C CG1   . VAL A 1 298 ? 119.675 115.151 130.125 1.00 63.91  ? 298 VAL A CG1   1 
ATOM 1427 C CG2   . VAL A 1 298 ? 120.916 114.617 128.031 1.00 63.91  ? 298 VAL A CG2   1 
ATOM 1428 N N     . THR A 1 299 ? 117.776 112.333 130.702 1.00 68.90  ? 299 THR A N     1 
ATOM 1429 C CA    . THR A 1 299 ? 116.581 112.066 131.490 1.00 68.90  ? 299 THR A CA    1 
ATOM 1430 C C     . THR A 1 299 ? 116.779 112.557 132.915 1.00 68.90  ? 299 THR A C     1 
ATOM 1431 O O     . THR A 1 299 ? 117.710 112.123 133.601 1.00 68.90  ? 299 THR A O     1 
ATOM 1432 C CB    . THR A 1 299 ? 116.249 110.571 131.495 1.00 68.90  ? 299 THR A CB    1 
ATOM 1433 O OG1   . THR A 1 299 ? 115.887 110.155 130.173 1.00 68.90  ? 299 THR A OG1   1 
ATOM 1434 C CG2   . THR A 1 299 ? 115.099 110.283 132.443 1.00 68.90  ? 299 THR A CG2   1 
ATOM 1435 N N     . ILE A 1 300 ? 115.895 113.456 133.361 1.00 69.82  ? 300 ILE A N     1 
ATOM 1436 C CA    . ILE A 1 300 ? 115.910 113.920 134.746 1.00 69.82  ? 300 ILE A CA    1 
ATOM 1437 C C     . ILE A 1 300 ? 114.905 113.168 135.608 1.00 69.82  ? 300 ILE A C     1 
ATOM 1438 O O     . ILE A 1 300 ? 114.798 113.444 136.813 1.00 69.82  ? 300 ILE A O     1 
ATOM 1439 C CB    . ILE A 1 300 ? 115.656 115.441 134.804 1.00 69.82  ? 300 ILE A CB    1 
ATOM 1440 C CG1   . ILE A 1 300 ? 116.370 116.135 133.646 1.00 69.82  ? 300 ILE A CG1   1 
ATOM 1441 C CG2   . ILE A 1 300 ? 116.177 116.031 136.101 1.00 69.82  ? 300 ILE A CG2   1 
ATOM 1442 C CD1   . ILE A 1 300 ? 116.224 117.636 133.652 1.00 69.82  ? 300 ILE A CD1   1 
ATOM 1443 N N     . GLY A 1 301 ? 114.172 112.219 135.034 1.00 73.32  ? 301 GLY A N     1 
ATOM 1444 C CA    . GLY A 1 301 ? 113.243 111.403 135.788 1.00 73.32  ? 301 GLY A CA    1 
ATOM 1445 C C     . GLY A 1 301 ? 111.861 111.390 135.173 1.00 73.32  ? 301 GLY A C     1 
ATOM 1446 O O     . GLY A 1 301 ? 111.185 110.357 135.164 1.00 73.32  ? 301 GLY A O     1 
ATOM 1447 N N     . LYS A 1 302 ? 111.450 112.516 134.594 1.00 73.76  ? 302 LYS A N     1 
ATOM 1448 C CA    . LYS A 1 302 ? 110.149 112.591 133.925 1.00 73.76  ? 302 LYS A CA    1 
ATOM 1449 C C     . LYS A 1 302 ? 110.249 113.413 132.647 1.00 73.76  ? 302 LYS A C     1 
ATOM 1450 O O     . LYS A 1 302 ? 109.354 113.363 131.802 1.00 73.76  ? 302 LYS A O     1 
ATOM 1451 C CB    . LYS A 1 302 ? 109.108 113.207 134.860 1.00 73.76  ? 302 LYS A CB    1 
ATOM 1452 C CG    . LYS A 1 302 ? 107.743 112.541 134.796 1.00 73.76  ? 302 LYS A CG    1 
ATOM 1453 C CD    . LYS A 1 302 ? 106.665 113.539 134.406 1.00 73.76  ? 302 LYS A CD    1 
ATOM 1454 C CE    . LYS A 1 302 ? 105.943 113.109 133.138 1.00 73.76  ? 302 LYS A CE    1 
ATOM 1455 N NZ    . LYS A 1 302 ? 106.598 111.941 132.487 1.00 73.76  ? 302 LYS A NZ    1 
ATOM 1456 N N     . ASP A 1 303 ? 111.333 114.165 132.495 1.00 72.37  ? 303 ASP A N     1 
ATOM 1457 C CA    . ASP A 1 303 ? 111.506 115.028 131.333 1.00 72.37  ? 303 ASP A CA    1 
ATOM 1458 C C     . ASP A 1 303 ? 112.643 114.475 130.488 1.00 72.37  ? 303 ASP A C     1 
ATOM 1459 O O     . ASP A 1 303 ? 113.760 114.301 130.985 1.00 72.37  ? 303 ASP A O     1 
ATOM 1460 C CB    . ASP A 1 303 ? 111.801 116.467 131.753 1.00 72.37  ? 303 ASP A CB    1 
ATOM 1461 C CG    . ASP A 1 303 ? 110.778 117.005 132.722 1.00 72.37  ? 303 ASP A CG    1 
ATOM 1462 O OD1   . ASP A 1 303 ? 109.575 116.727 132.536 1.00 72.37  ? 303 ASP A OD1   1 
ATOM 1463 O OD2   . ASP A 1 303 ? 111.178 117.702 133.677 1.00 72.37  ? 303 ASP A OD2   1 
ATOM 1464 N N     . TRP A 1 304 ? 112.360 114.210 129.219 1.00 67.61  ? 304 TRP A N     1 
ATOM 1465 C CA    . TRP A 1 304 ? 113.318 113.611 128.304 1.00 67.61  ? 304 TRP A CA    1 
ATOM 1466 C C     . TRP A 1 304 ? 113.597 114.534 127.125 1.00 67.61  ? 304 TRP A C     1 
ATOM 1467 O O     . TRP A 1 304 ? 112.677 115.114 126.542 1.00 67.61  ? 304 TRP A O     1 
ATOM 1468 C CB    . TRP A 1 304 ? 112.816 112.248 127.819 1.00 67.61  ? 304 TRP A CB    1 
ATOM 1469 C CG    . TRP A 1 304 ? 111.523 112.320 127.073 1.00 67.61  ? 304 TRP A CG    1 
ATOM 1470 C CD1   . TRP A 1 304 ? 110.272 112.232 127.606 1.00 67.61  ? 304 TRP A CD1   1 
ATOM 1471 C CD2   . TRP A 1 304 ? 111.345 112.542 125.669 1.00 67.61  ? 304 TRP A CD2   1 
ATOM 1472 N NE1   . TRP A 1 304 ? 109.324 112.358 126.620 1.00 67.61  ? 304 TRP A NE1   1 
ATOM 1473 C CE2   . TRP A 1 304 ? 109.957 112.555 125.422 1.00 67.61  ? 304 TRP A CE2   1 
ATOM 1474 C CE3   . TRP A 1 304 ? 112.223 112.720 124.595 1.00 67.61  ? 304 TRP A CE3   1 
ATOM 1475 C CZ2   . TRP A 1 304 ? 109.428 112.738 124.147 1.00 67.61  ? 304 TRP A CZ2   1 
ATOM 1476 C CZ3   . TRP A 1 304 ? 111.696 112.903 123.331 1.00 67.61  ? 304 TRP A CZ3   1 
ATOM 1477 C CH2   . TRP A 1 304 ? 110.311 112.910 123.117 1.00 67.61  ? 304 TRP A CH2   1 
ATOM 1478 N N     . ILE A 1 305 ? 114.877 114.665 126.786 1.00 62.86  ? 305 ILE A N     1 
ATOM 1479 C CA    . ILE A 1 305 ? 115.338 115.512 125.693 1.00 62.86  ? 305 ILE A CA    1 
ATOM 1480 C C     . ILE A 1 305 ? 116.226 114.685 124.775 1.00 62.86  ? 305 ILE A C     1 
ATOM 1481 O O     . ILE A 1 305 ? 117.187 114.057 125.234 1.00 62.86  ? 305 ILE A O     1 
ATOM 1482 C CB    . ILE A 1 305 ? 116.092 116.750 126.211 1.00 62.86  ? 305 ILE A CB    1 
ATOM 1483 C CG1   . ILE A 1 305 ? 115.105 117.734 126.827 1.00 62.86  ? 305 ILE A CG1   1 
ATOM 1484 C CG2   . ILE A 1 305 ? 116.885 117.404 125.098 1.00 62.86  ? 305 ILE A CG2   1 
ATOM 1485 C CD1   . ILE A 1 305 ? 114.037 118.163 125.854 1.00 62.86  ? 305 ILE A CD1   1 
ATOM 1486 N N     . VAL A 1 306 ? 115.909 114.691 123.485 1.00 64.51  ? 306 VAL A N     1 
ATOM 1487 C CA    . VAL A 1 306 ? 116.653 113.949 122.475 1.00 64.51  ? 306 VAL A CA    1 
ATOM 1488 C C     . VAL A 1 306 ? 117.333 114.973 121.578 1.00 64.51  ? 306 VAL A C     1 
ATOM 1489 O O     . VAL A 1 306 ? 116.672 115.723 120.853 1.00 64.51  ? 306 VAL A O     1 
ATOM 1490 C CB    . VAL A 1 306 ? 115.749 113.008 121.672 1.00 64.51  ? 306 VAL A CB    1 
ATOM 1491 C CG1   . VAL A 1 306 ? 116.526 112.366 120.541 1.00 64.51  ? 306 VAL A CG1   1 
ATOM 1492 C CG2   . VAL A 1 306 ? 115.166 111.945 122.580 1.00 64.51  ? 306 VAL A CG2   1 
ATOM 1493 N N     . MET A 1 307 ? 118.657 115.009 121.626 1.00 68.27  ? 307 MET A N     1 
ATOM 1494 C CA    . MET A 1 307 ? 119.440 115.937 120.831 1.00 68.27  ? 307 MET A CA    1 
ATOM 1495 C C     . MET A 1 307 ? 120.084 115.220 119.644 1.00 68.27  ? 307 MET A C     1 
ATOM 1496 O O     . MET A 1 307 ? 120.176 113.991 119.599 1.00 68.27  ? 307 MET A O     1 
ATOM 1497 C CB    . MET A 1 307 ? 120.492 116.607 121.709 1.00 68.27  ? 307 MET A CB    1 
ATOM 1498 C CG    . MET A 1 307 ? 120.028 116.796 123.142 1.00 68.27  ? 307 MET A CG    1 
ATOM 1499 S SD    . MET A 1 307 ? 121.298 117.422 124.250 1.00 68.27  ? 307 MET A SD    1 
ATOM 1500 C CE    . MET A 1 307 ? 122.101 115.896 124.721 1.00 68.27  ? 307 MET A CE    1 
ATOM 1501 N N     . ASP A 1 308 ? 120.529 116.010 118.670 1.00 73.39  ? 308 ASP A N     1 
ATOM 1502 C CA    . ASP A 1 308 ? 121.152 115.497 117.457 1.00 73.39  ? 308 ASP A CA    1 
ATOM 1503 C C     . ASP A 1 308 ? 122.664 115.506 117.637 1.00 73.39  ? 308 ASP A C     1 
ATOM 1504 O O     . ASP A 1 308 ? 123.255 116.558 117.904 1.00 73.39  ? 308 ASP A O     1 
ATOM 1505 C CB    . ASP A 1 308 ? 120.745 116.329 116.243 1.00 73.39  ? 308 ASP A CB    1 
ATOM 1506 C CG    . ASP A 1 308 ? 120.518 115.483 115.007 1.00 73.39  ? 308 ASP A CG    1 
ATOM 1507 O OD1   . ASP A 1 308 ? 120.983 114.324 114.985 1.00 73.39  ? 308 ASP A OD1   1 
ATOM 1508 O OD2   . ASP A 1 308 ? 119.867 115.973 114.061 1.00 73.39  ? 308 ASP A OD2   1 
ATOM 1509 N N     . ALA A 1 309 ? 123.284 114.337 117.489 1.00 65.85  ? 309 ALA A N     1 
ATOM 1510 C CA    . ALA A 1 309 ? 124.693 114.165 117.807 1.00 65.85  ? 309 ALA A CA    1 
ATOM 1511 C C     . ALA A 1 309 ? 125.615 114.351 116.610 1.00 65.85  ? 309 ALA A C     1 
ATOM 1512 O O     . ALA A 1 309 ? 126.840 114.311 116.779 1.00 65.85  ? 309 ALA A O     1 
ATOM 1513 C CB    . ALA A 1 309 ? 124.922 112.783 118.420 1.00 65.85  ? 309 ALA A CB    1 
ATOM 1514 N N     . ARG A 1 310 ? 125.068 114.547 115.409 1.00 67.86  ? 310 ARG A N     1 
ATOM 1515 C CA    . ARG A 1 310 ? 125.923 114.774 114.250 1.00 67.86  ? 310 ARG A CA    1 
ATOM 1516 C C     . ARG A 1 310 ? 126.721 116.059 114.400 1.00 67.86  ? 310 ARG A C     1 
ATOM 1517 O O     . ARG A 1 310 ? 127.801 116.195 113.811 1.00 67.86  ? 310 ARG A O     1 
ATOM 1518 C CB    . ARG A 1 310 ? 125.083 114.790 112.974 1.00 67.86  ? 310 ARG A CB    1 
ATOM 1519 C CG    . ARG A 1 310 ? 124.365 113.471 112.719 1.00 67.86  ? 310 ARG A CG    1 
ATOM 1520 C CD    . ARG A 1 310 ? 123.316 113.595 111.630 1.00 67.86  ? 310 ARG A CD    1 
ATOM 1521 N NE    . ARG A 1 310 ? 122.089 114.212 112.114 1.00 67.86  ? 310 ARG A NE    1 
ATOM 1522 C CZ    . ARG A 1 310 ? 120.969 114.285 111.412 1.00 67.86  ? 310 ARG A CZ    1 
ATOM 1523 N NH1   . ARG A 1 310 ? 120.883 113.777 110.194 1.00 67.86  ? 310 ARG A NH1   1 
ATOM 1524 N NH2   . ARG A 1 310 ? 119.907 114.882 111.944 1.00 67.86  ? 310 ARG A NH2   1 
ATOM 1525 N N     . GLY A 1 311 ? 126.222 117.001 115.201 1.00 67.59  ? 311 GLY A N     1 
ATOM 1526 C CA    . GLY A 1 311 ? 127.038 118.143 115.570 1.00 67.59  ? 311 GLY A CA    1 
ATOM 1527 C C     . GLY A 1 311 ? 128.282 117.727 116.328 1.00 67.59  ? 311 GLY A C     1 
ATOM 1528 O O     . GLY A 1 311 ? 129.377 118.230 116.069 1.00 67.59  ? 311 GLY A O     1 
ATOM 1529 N N     . LEU A 1 312 ? 128.133 116.788 117.263 1.00 67.35  ? 312 LEU A N     1 
ATOM 1530 C CA    . LEU A 1 312 ? 129.292 116.251 117.967 1.00 67.35  ? 312 LEU A CA    1 
ATOM 1531 C C     . LEU A 1 312 ? 130.223 115.512 117.014 1.00 67.35  ? 312 LEU A C     1 
ATOM 1532 O O     . LEU A 1 312 ? 131.451 115.599 117.140 1.00 67.35  ? 312 LEU A O     1 
ATOM 1533 C CB    . LEU A 1 312 ? 128.835 115.329 119.094 1.00 67.35  ? 312 LEU A CB    1 
ATOM 1534 C CG    . LEU A 1 312 ? 127.963 115.958 120.178 1.00 67.35  ? 312 LEU A CG    1 
ATOM 1535 C CD1   . LEU A 1 312 ? 127.339 114.884 121.054 1.00 67.35  ? 312 LEU A CD1   1 
ATOM 1536 C CD2   . LEU A 1 312 ? 128.772 116.942 121.013 1.00 67.35  ? 312 LEU A CD2   1 
ATOM 1537 N N     . LEU A 1 313 ? 129.654 114.764 116.064 1.00 67.28  ? 313 LEU A N     1 
ATOM 1538 C CA    . LEU A 1 313 ? 130.474 114.092 115.058 1.00 67.28  ? 313 LEU A CA    1 
ATOM 1539 C C     . LEU A 1 313 ? 131.340 115.089 114.299 1.00 67.28  ? 313 LEU A C     1 
ATOM 1540 O O     . LEU A 1 313 ? 132.553 114.895 114.146 1.00 67.28  ? 313 LEU A O     1 
ATOM 1541 C CB    . LEU A 1 313 ? 129.588 113.323 114.082 1.00 67.28  ? 313 LEU A CB    1 
ATOM 1542 C CG    . LEU A 1 313 ? 129.268 111.864 114.378 1.00 67.28  ? 313 LEU A CG    1 
ATOM 1543 C CD1   . LEU A 1 313 ? 128.299 111.751 115.533 1.00 67.28  ? 313 LEU A CD1   1 
ATOM 1544 C CD2   . LEU A 1 313 ? 128.706 111.206 113.128 1.00 67.28  ? 313 LEU A CD2   1 
ATOM 1545 N N     . ARG A 1 314 ? 130.727 116.159 113.797 1.00 67.56  ? 314 ARG A N     1 
ATOM 1546 C CA    . ARG A 1 314 ? 131.500 117.146 113.058 1.00 67.56  ? 314 ARG A CA    1 
ATOM 1547 C C     . ARG A 1 314 ? 132.508 117.837 113.963 1.00 67.56  ? 314 ARG A C     1 
ATOM 1548 O O     . ARG A 1 314 ? 133.627 118.139 113.538 1.00 67.56  ? 314 ARG A O     1 
ATOM 1549 C CB    . ARG A 1 314 ? 130.581 118.168 112.401 1.00 67.56  ? 314 ARG A CB    1 
ATOM 1550 C CG    . ARG A 1 314 ? 131.293 118.983 111.354 1.00 67.56  ? 314 ARG A CG    1 
ATOM 1551 C CD    . ARG A 1 314 ? 130.602 120.293 111.124 1.00 67.56  ? 314 ARG A CD    1 
ATOM 1552 N NE    . ARG A 1 314 ? 130.724 121.160 112.286 1.00 67.56  ? 314 ARG A NE    1 
ATOM 1553 C CZ    . ARG A 1 314 ? 130.381 122.438 112.291 1.00 67.56  ? 314 ARG A CZ    1 
ATOM 1554 N NH1   . ARG A 1 314 ? 129.911 123.026 111.207 1.00 67.56  ? 314 ARG A NH1   1 
ATOM 1555 N NH2   . ARG A 1 314 ? 130.520 123.143 113.409 1.00 67.56  ? 314 ARG A NH2   1 
ATOM 1556 N N     . ALA A 1 315 ? 132.132 118.092 115.217 1.00 66.94  ? 315 ALA A N     1 
ATOM 1557 C CA    . ALA A 1 315 ? 133.046 118.750 116.139 1.00 66.94  ? 315 ALA A CA    1 
ATOM 1558 C C     . ALA A 1 315 ? 134.279 117.901 116.410 1.00 66.94  ? 315 ALA A C     1 
ATOM 1559 O O     . ALA A 1 315 ? 135.382 118.443 116.553 1.00 66.94  ? 315 ALA A O     1 
ATOM 1560 C CB    . ALA A 1 315 ? 132.327 119.076 117.447 1.00 66.94  ? 315 ALA A CB    1 
ATOM 1561 N N     . VAL A 1 316 ? 134.121 116.583 116.485 1.00 69.26  ? 316 VAL A N     1 
ATOM 1562 C CA    . VAL A 1 316 ? 135.271 115.727 116.753 1.00 69.26  ? 316 VAL A CA    1 
ATOM 1563 C C     . VAL A 1 316 ? 136.097 115.473 115.491 1.00 69.26  ? 316 VAL A C     1 
ATOM 1564 O O     . VAL A 1 316 ? 137.324 115.356 115.575 1.00 69.26  ? 316 VAL A O     1 
ATOM 1565 C CB    . VAL A 1 316 ? 134.827 114.410 117.416 1.00 69.26  ? 316 VAL A CB    1 
ATOM 1566 C CG1   . VAL A 1 316 ? 133.891 113.635 116.524 1.00 69.26  ? 316 VAL A CG1   1 
ATOM 1567 C CG2   . VAL A 1 316 ? 136.026 113.563 117.786 1.00 69.26  ? 316 VAL A CG2   1 
ATOM 1568 N N     . TYR A 1 317 ? 135.467 115.402 114.315 1.00 71.58  ? 317 TYR A N     1 
ATOM 1569 C CA    . TYR A 1 317 ? 136.249 115.299 113.086 1.00 71.58  ? 317 TYR A CA    1 
ATOM 1570 C C     . TYR A 1 317 ? 136.922 116.608 112.700 1.00 71.58  ? 317 TYR A C     1 
ATOM 1571 O O     . TYR A 1 317 ? 137.880 116.585 111.920 1.00 71.58  ? 317 TYR A O     1 
ATOM 1572 C CB    . TYR A 1 317 ? 135.382 114.818 111.919 1.00 71.58  ? 317 TYR A CB    1 
ATOM 1573 C CG    . TYR A 1 317 ? 134.738 113.477 112.146 1.00 71.58  ? 317 TYR A CG    1 
ATOM 1574 C CD1   . TYR A 1 317 ? 135.457 112.427 112.693 1.00 71.58  ? 317 TYR A CD1   1 
ATOM 1575 C CD2   . TYR A 1 317 ? 133.415 113.256 111.805 1.00 71.58  ? 317 TYR A CD2   1 
ATOM 1576 C CE1   . TYR A 1 317 ? 134.873 111.196 112.901 1.00 71.58  ? 317 TYR A CE1   1 
ATOM 1577 C CE2   . TYR A 1 317 ? 132.822 112.032 112.010 1.00 71.58  ? 317 TYR A CE2   1 
ATOM 1578 C CZ    . TYR A 1 317 ? 133.555 111.003 112.557 1.00 71.58  ? 317 TYR A CZ    1 
ATOM 1579 O OH    . TYR A 1 317 ? 132.966 109.776 112.762 1.00 71.58  ? 317 TYR A OH    1 
ATOM 1580 N N     . TRP A 1 318 ? 136.455 117.740 113.224 1.00 73.35  ? 318 TRP A N     1 
ATOM 1581 C CA    . TRP A 1 318 ? 137.047 119.027 112.888 1.00 73.35  ? 318 TRP A CA    1 
ATOM 1582 C C     . TRP A 1 318 ? 138.399 119.234 113.555 1.00 73.35  ? 318 TRP A C     1 
ATOM 1583 O O     . TRP A 1 318 ? 139.261 119.920 112.995 1.00 73.35  ? 318 TRP A O     1 
ATOM 1584 C CB    . TRP A 1 318 ? 136.088 120.149 113.288 1.00 73.35  ? 318 TRP A CB    1 
ATOM 1585 C CG    . TRP A 1 318 ? 136.558 121.514 112.929 1.00 73.35  ? 318 TRP A CG    1 
ATOM 1586 C CD1   . TRP A 1 318 ? 137.104 122.437 113.766 1.00 73.35  ? 318 TRP A CD1   1 
ATOM 1587 C CD2   . TRP A 1 318 ? 136.521 122.118 111.633 1.00 73.35  ? 318 TRP A CD2   1 
ATOM 1588 N NE1   . TRP A 1 318 ? 137.415 123.579 113.073 1.00 73.35  ? 318 TRP A NE1   1 
ATOM 1589 C CE2   . TRP A 1 318 ? 137.064 123.410 111.760 1.00 73.35  ? 318 TRP A CE2   1 
ATOM 1590 C CE3   . TRP A 1 318 ? 136.083 121.691 110.375 1.00 73.35  ? 318 TRP A CE3   1 
ATOM 1591 C CZ2   . TRP A 1 318 ? 137.182 124.281 110.678 1.00 73.35  ? 318 TRP A CZ2   1 
ATOM 1592 C CZ3   . TRP A 1 318 ? 136.199 122.557 109.302 1.00 73.35  ? 318 TRP A CZ3   1 
ATOM 1593 C CH2   . TRP A 1 318 ? 136.745 123.836 109.461 1.00 73.35  ? 318 TRP A CH2   1 
ATOM 1594 N N     . ARG A 1 319 ? 138.604 118.658 114.736 1.00 68.82  ? 319 ARG A N     1 
ATOM 1595 C CA    . ARG A 1 319 ? 139.814 118.902 115.507 1.00 68.82  ? 319 ARG A CA    1 
ATOM 1596 C C     . ARG A 1 319 ? 140.954 117.951 115.170 1.00 68.82  ? 319 ARG A C     1 
ATOM 1597 O O     . ARG A 1 319 ? 142.096 118.227 115.550 1.00 68.82  ? 319 ARG A O     1 
ATOM 1598 C CB    . ARG A 1 319 ? 139.503 118.822 117.004 1.00 68.82  ? 319 ARG A CB    1 
ATOM 1599 C CG    . ARG A 1 319 ? 140.328 119.768 117.859 1.00 68.82  ? 319 ARG A CG    1 
ATOM 1600 C CD    . ARG A 1 319 ? 139.937 121.217 117.612 1.00 68.82  ? 319 ARG A CD    1 
ATOM 1601 N NE    . ARG A 1 319 ? 138.497 121.382 117.460 1.00 68.82  ? 319 ARG A NE    1 
ATOM 1602 C CZ    . ARG A 1 319 ? 137.639 121.464 118.467 1.00 68.82  ? 319 ARG A CZ    1 
ATOM 1603 N NH1   . ARG A 1 319 ? 138.043 121.400 119.725 1.00 68.82  ? 319 ARG A NH1   1 
ATOM 1604 N NH2   . ARG A 1 319 ? 136.345 121.616 118.206 1.00 68.82  ? 319 ARG A NH2   1 
ATOM 1605 N N     . GLY A 1 320 ? 140.686 116.847 114.476 1.00 73.87  ? 320 GLY A N     1 
ATOM 1606 C CA    . GLY A 1 320 ? 141.769 115.993 114.029 1.00 73.87  ? 320 GLY A CA    1 
ATOM 1607 C C     . GLY A 1 320 ? 141.563 114.499 114.184 1.00 73.87  ? 320 GLY A C     1 
ATOM 1608 O O     . GLY A 1 320 ? 142.242 113.712 113.519 1.00 73.87  ? 320 GLY A O     1 
ATOM 1609 N N     . ILE A 1 321 ? 140.639 114.091 115.057 1.00 71.53  ? 321 ILE A N     1 
ATOM 1610 C CA    . ILE A 1 321 ? 140.444 112.670 115.310 1.00 71.53  ? 321 ILE A CA    1 
ATOM 1611 C C     . ILE A 1 321 ? 139.926 111.972 114.053 1.00 71.53  ? 321 ILE A C     1 
ATOM 1612 O O     . ILE A 1 321 ? 139.068 112.493 113.328 1.00 71.53  ? 321 ILE A O     1 
ATOM 1613 C CB    . ILE A 1 321 ? 139.496 112.462 116.503 1.00 71.53  ? 321 ILE A CB    1 
ATOM 1614 C CG1   . ILE A 1 321 ? 140.135 113.021 117.772 1.00 71.53  ? 321 ILE A CG1   1 
ATOM 1615 C CG2   . ILE A 1 321 ? 139.176 110.995 116.692 1.00 71.53  ? 321 ILE A CG2   1 
ATOM 1616 C CD1   . ILE A 1 321 ? 139.271 112.911 118.990 1.00 71.53  ? 321 ILE A CD1   1 
ATOM 1617 N N     . ALA A 1 322 ? 140.462 110.780 113.792 1.00 71.62  ? 322 ALA A N     1 
ATOM 1618 C CA    . ALA A 1 322 ? 140.158 110.035 112.579 1.00 71.62  ? 322 ALA A CA    1 
ATOM 1619 C C     . ALA A 1 322 ? 138.706 109.566 112.566 1.00 71.62  ? 322 ALA A C     1 
ATOM 1620 O O     . ALA A 1 322 ? 137.923 109.839 113.479 1.00 71.62  ? 322 ALA A O     1 
ATOM 1621 C CB    . ALA A 1 322 ? 141.093 108.834 112.440 1.00 71.62  ? 322 ALA A CB    1 
ATOM 1622 N N     . LYS A 1 323 ? 138.348 108.856 111.501 1.00 72.36  ? 323 LYS A N     1 
ATOM 1623 C CA    . LYS A 1 323 ? 136.976 108.434 111.259 1.00 72.36  ? 323 LYS A CA    1 
ATOM 1624 C C     . LYS A 1 323 ? 136.890 106.916 111.248 1.00 72.36  ? 323 LYS A C     1 
ATOM 1625 O O     . LYS A 1 323 ? 137.861 106.229 110.918 1.00 72.36  ? 323 LYS A O     1 
ATOM 1626 C CB    . LYS A 1 323 ? 136.473 109.013 109.933 1.00 72.36  ? 323 LYS A CB    1 
ATOM 1627 C CG    . LYS A 1 323 ? 135.038 108.679 109.549 1.00 72.36  ? 323 LYS A CG    1 
ATOM 1628 C CD    . LYS A 1 323 ? 134.969 107.455 108.644 1.00 72.36  ? 323 LYS A CD    1 
ATOM 1629 C CE    . LYS A 1 323 ? 135.537 107.756 107.267 1.00 72.36  ? 323 LYS A CE    1 
ATOM 1630 N NZ    . LYS A 1 323 ? 135.469 106.574 106.364 1.00 72.36  ? 323 LYS A NZ    1 
ATOM 1631 N N     . PRO A 1 324 ? 135.719 106.396 111.611 1.00 75.68  ? 324 PRO A N     1 
ATOM 1632 C CA    . PRO A 1 324 ? 135.475 104.972 111.584 1.00 75.68  ? 324 PRO A CA    1 
ATOM 1633 C C     . PRO A 1 324 ? 135.822 104.240 112.857 1.00 75.68  ? 324 PRO A C     1 
ATOM 1634 O O     . PRO A 1 324 ? 135.140 103.264 113.195 1.00 75.68  ? 324 PRO A O     1 
ATOM 1635 N N     . GLY A 1 325 ? 136.857 104.674 113.577 1.00 79.86  ? 325 GLY A N     1 
ATOM 1636 C CA    . GLY A 1 325 ? 137.108 104.182 114.921 1.00 79.86  ? 325 GLY A CA    1 
ATOM 1637 C C     . GLY A 1 325 ? 136.128 104.741 115.937 1.00 79.86  ? 325 GLY A C     1 
ATOM 1638 O O     . GLY A 1 325 ? 136.085 104.246 117.067 1.00 79.86  ? 325 GLY A O     1 
ATOM 1639 N N     . LEU A 1 326 ? 135.350 105.752 115.563 1.00 72.35  ? 326 LEU A N     1 
ATOM 1640 C CA    . LEU A 1 326 ? 134.356 106.314 116.462 1.00 72.35  ? 326 LEU A CA    1 
ATOM 1641 C C     . LEU A 1 326 ? 133.047 105.549 116.338 1.00 72.35  ? 326 LEU A C     1 
ATOM 1642 O O     . LEU A 1 326 ? 132.518 105.373 115.236 1.00 72.35  ? 326 LEU A O     1 
ATOM 1643 C CB    . LEU A 1 326 ? 134.133 107.791 116.151 1.00 72.35  ? 326 LEU A CB    1 
ATOM 1644 C CG    . LEU A 1 326 ? 135.142 108.791 116.702 1.00 72.35  ? 326 LEU A CG    1 
ATOM 1645 C CD1   . LEU A 1 326 ? 136.466 108.688 115.984 1.00 72.35  ? 326 LEU A CD1   1 
ATOM 1646 C CD2   . LEU A 1 326 ? 134.581 110.184 116.577 1.00 72.35  ? 326 LEU A CD2   1 
ATOM 1647 N N     . SER A 1 327 ? 132.532 105.083 117.472 1.00 72.34  ? 327 SER A N     1 
ATOM 1648 C CA    . SER A 1 327 ? 131.247 104.399 117.511 1.00 72.34  ? 327 SER A CA    1 
ATOM 1649 C C     . SER A 1 327 ? 130.420 104.926 118.676 1.00 72.34  ? 327 SER A C     1 
ATOM 1650 O O     . SER A 1 327 ? 130.761 105.956 119.264 1.00 72.34  ? 327 SER A O     1 
ATOM 1651 C CB    . SER A 1 327 ? 131.446 102.888 117.622 1.00 72.34  ? 327 SER A CB    1 
ATOM 1652 O OG    . SER A 1 327 ? 130.208 102.208 117.551 1.00 72.34  ? 327 SER A OG    1 
ATOM 1653 N N     . LEU A 1 328 ? 129.329 104.243 119.007 1.00 72.37  ? 328 LEU A N     1 
ATOM 1654 C CA    . LEU A 1 328 ? 128.580 104.587 120.207 1.00 72.37  ? 328 LEU A CA    1 
ATOM 1655 C C     . LEU A 1 328 ? 129.456 104.377 121.436 1.00 72.37  ? 328 LEU A C     1 
ATOM 1656 O O     . LEU A 1 328 ? 130.386 103.564 121.421 1.00 72.37  ? 328 LEU A O     1 
ATOM 1657 C CB    . LEU A 1 328 ? 127.307 103.746 120.320 1.00 72.37  ? 328 LEU A CB    1 
ATOM 1658 C CG    . LEU A 1 328 ? 127.419 102.280 120.753 1.00 72.37  ? 328 LEU A CG    1 
ATOM 1659 C CD1   . LEU A 1 328 ? 126.057 101.756 121.182 1.00 72.37  ? 328 LEU A CD1   1 
ATOM 1660 C CD2   . LEU A 1 328 ? 127.997 101.398 119.657 1.00 72.37  ? 328 LEU A CD2   1 
ATOM 1661 N N     . LYS A 1 329 ? 129.170 105.135 122.497 1.00 69.82  ? 329 LYS A N     1 
ATOM 1662 C CA    . LYS A 1 329 ? 129.918 105.126 123.756 1.00 69.82  ? 329 LYS A CA    1 
ATOM 1663 C C     . LYS A 1 329 ? 131.340 105.646 123.596 1.00 69.82  ? 329 LYS A C     1 
ATOM 1664 O O     . LYS A 1 329 ? 132.109 105.647 124.563 1.00 69.82  ? 329 LYS A O     1 
ATOM 1665 C CB    . LYS A 1 329 ? 129.962 103.734 124.406 1.00 69.82  ? 329 LYS A CB    1 
ATOM 1666 C CG    . LYS A 1 329 ? 128.670 102.915 124.357 1.00 69.82  ? 329 LYS A CG    1 
ATOM 1667 C CD    . LYS A 1 329 ? 127.433 103.731 124.712 1.00 69.82  ? 329 LYS A CD    1 
ATOM 1668 C CE    . LYS A 1 329 ? 127.464 104.153 126.175 1.00 69.82  ? 329 LYS A CE    1 
ATOM 1669 N NZ    . LYS A 1 329 ? 126.139 104.629 126.656 1.00 69.82  ? 329 LYS A NZ    1 
ATOM 1670 N N     . GLU A 1 330 ? 131.716 106.091 122.400 1.00 64.71  ? 330 GLU A N     1 
ATOM 1671 C CA    . GLU A 1 330 ? 133.040 106.655 122.178 1.00 64.71  ? 330 GLU A CA    1 
ATOM 1672 C C     . GLU A 1 330 ? 133.002 108.060 121.613 1.00 64.71  ? 330 GLU A C     1 
ATOM 1673 O O     . GLU A 1 330 ? 134.047 108.714 121.578 1.00 64.71  ? 330 GLU A O     1 
ATOM 1674 C CB    . GLU A 1 330 ? 133.859 105.760 121.237 1.00 64.71  ? 330 GLU A CB    1 
ATOM 1675 C CG    . GLU A 1 330 ? 134.216 104.405 121.825 1.00 64.71  ? 330 GLU A CG    1 
ATOM 1676 C CD    . GLU A 1 330 ? 135.006 103.542 120.862 1.00 64.71  ? 330 GLU A CD    1 
ATOM 1677 O OE1   . GLU A 1 330 ? 135.167 103.950 119.694 1.00 64.71  ? 330 GLU A OE1   1 
ATOM 1678 O OE2   . GLU A 1 330 ? 135.466 102.456 121.273 1.00 64.71  ? 330 GLU A OE2   1 
ATOM 1679 N N     . LEU A 1 331 ? 131.848 108.541 121.154 1.00 66.44  ? 331 LEU A N     1 
ATOM 1680 C CA    . LEU A 1 331 ? 131.713 109.945 120.790 1.00 66.44  ? 331 LEU A CA    1 
ATOM 1681 C C     . LEU A 1 331 ? 131.528 110.804 122.033 1.00 66.44  ? 331 LEU A C     1 
ATOM 1682 O O     . LEU A 1 331 ? 132.304 111.732 122.286 1.00 66.44  ? 331 LEU A O     1 
ATOM 1683 C CB    . LEU A 1 331 ? 130.536 110.123 119.831 1.00 66.44  ? 331 LEU A CB    1 
ATOM 1684 C CG    . LEU A 1 331 ? 130.177 111.563 119.467 1.00 66.44  ? 331 LEU A CG    1 
ATOM 1685 C CD1   . LEU A 1 331 ? 131.063 112.079 118.348 1.00 66.44  ? 331 LEU A CD1   1 
ATOM 1686 C CD2   . LEU A 1 331 ? 128.706 111.665 119.096 1.00 66.44  ? 331 LEU A CD2   1 
ATOM 1687 N N     . LEU A 1 332 ? 130.507 110.485 122.835 1.00 62.09  ? 332 LEU A N     1 
ATOM 1688 C CA    . LEU A 1 332 ? 130.203 111.251 124.038 1.00 62.09  ? 332 LEU A CA    1 
ATOM 1689 C C     . LEU A 1 332 ? 131.375 111.303 125.004 1.00 62.09  ? 332 LEU A C     1 
ATOM 1690 O O     . LEU A 1 332 ? 131.487 112.263 125.773 1.00 62.09  ? 332 LEU A O     1 
ATOM 1691 C CB    . LEU A 1 332 ? 128.987 110.647 124.740 1.00 62.09  ? 332 LEU A CB    1 
ATOM 1692 C CG    . LEU A 1 332 ? 127.775 110.324 123.867 1.00 62.09  ? 332 LEU A CG    1 
ATOM 1693 C CD1   . LEU A 1 332 ? 126.667 109.705 124.694 1.00 62.09  ? 332 LEU A CD1   1 
ATOM 1694 C CD2   . LEU A 1 332 ? 127.280 111.574 123.155 1.00 62.09  ? 332 LEU A CD2   1 
ATOM 1695 N N     . GLY A 1 333 ? 132.250 110.296 124.977 1.00 65.00  ? 333 GLY A N     1 
ATOM 1696 C CA    . GLY A 1 333 ? 133.361 110.265 125.913 1.00 65.00  ? 333 GLY A CA    1 
ATOM 1697 C C     . GLY A 1 333 ? 134.290 111.455 125.771 1.00 65.00  ? 333 GLY A C     1 
ATOM 1698 O O     . GLY A 1 333 ? 134.850 111.938 126.758 1.00 65.00  ? 333 GLY A O     1 
ATOM 1699 N N     . PHE A 1 334 ? 134.471 111.943 124.543 1.00 69.76  ? 334 PHE A N     1 
ATOM 1700 C CA    . PHE A 1 334 ? 135.348 113.086 124.333 1.00 69.76  ? 334 PHE A CA    1 
ATOM 1701 C C     . PHE A 1 334 ? 134.755 114.379 124.877 1.00 69.76  ? 334 PHE A C     1 
ATOM 1702 O O     . PHE A 1 334 ? 135.490 115.356 125.050 1.00 69.76  ? 334 PHE A O     1 
ATOM 1703 C CB    . PHE A 1 334 ? 135.663 113.244 122.846 1.00 69.76  ? 334 PHE A CB    1 
ATOM 1704 C CG    . PHE A 1 334 ? 136.546 112.161 122.297 1.00 69.76  ? 334 PHE A CG    1 
ATOM 1705 C CD1   . PHE A 1 334 ? 137.921 112.233 122.440 1.00 69.76  ? 334 PHE A CD1   1 
ATOM 1706 C CD2   . PHE A 1 334 ? 136.003 111.075 121.634 1.00 69.76  ? 334 PHE A CD2   1 
ATOM 1707 C CE1   . PHE A 1 334 ? 138.736 111.238 121.938 1.00 69.76  ? 334 PHE A CE1   1 
ATOM 1708 C CE2   . PHE A 1 334 ? 136.814 110.081 121.128 1.00 69.76  ? 334 PHE A CE2   1 
ATOM 1709 C CZ    . PHE A 1 334 ? 138.182 110.164 121.280 1.00 69.76  ? 334 PHE A CZ    1 
ATOM 1710 N N     . PHE A 1 335 ? 133.456 114.405 125.157 1.00 68.11  ? 335 PHE A N     1 
ATOM 1711 C CA    . PHE A 1 335 ? 132.785 115.584 125.679 1.00 68.11  ? 335 PHE A CA    1 
ATOM 1712 C C     . PHE A 1 335 ? 132.476 115.405 127.158 1.00 68.11  ? 335 PHE A C     1 
ATOM 1713 O O     . PHE A 1 335 ? 132.315 114.287 127.653 1.00 68.11  ? 335 PHE A O     1 
ATOM 1714 C CB    . PHE A 1 335 ? 131.495 115.870 124.905 1.00 68.11  ? 335 PHE A CB    1 
ATOM 1715 C CG    . PHE A 1 335 ? 131.622 115.667 123.425 1.00 68.11  ? 335 PHE A CG    1 
ATOM 1716 C CD1   . PHE A 1 335 ? 132.317 116.575 122.646 1.00 68.11  ? 335 PHE A CD1   1 
ATOM 1717 C CD2   . PHE A 1 335 ? 131.055 114.564 122.813 1.00 68.11  ? 335 PHE A CD2   1 
ATOM 1718 C CE1   . PHE A 1 335 ? 132.438 116.389 121.289 1.00 68.11  ? 335 PHE A CE1   1 
ATOM 1719 C CE2   . PHE A 1 335 ? 131.177 114.375 121.452 1.00 68.11  ? 335 PHE A CE2   1 
ATOM 1720 C CZ    . PHE A 1 335 ? 131.872 115.288 120.690 1.00 68.11  ? 335 PHE A CZ    1 
ATOM 1721 N N     . SER A 1 336 ? 132.376 116.512 127.876 1.00 70.31  ? 336 SER A N     1 
ATOM 1722 C CA    . SER A 1 336 ? 132.031 116.469 129.282 1.00 70.31  ? 336 SER A CA    1 
ATOM 1723 C C     . SER A 1 336 ? 130.651 115.912 129.443 1.00 70.31  ? 336 SER A C     1 
ATOM 1724 O O     . SER A 1 336 ? 129.771 116.135 128.609 1.00 70.31  ? 336 SER A O     1 
ATOM 1725 C CB    . SER A 1 336 ? 132.082 117.860 129.903 1.00 70.31  ? 336 SER A CB    1 
ATOM 1726 O OG    . SER A 1 336 ? 133.383 118.403 129.824 1.00 70.31  ? 336 SER A OG    1 
ATOM 1727 N N     . GLY A 1 337 ? 130.451 115.203 130.529 1.00 64.49  ? 337 GLY A N     1 
ATOM 1728 C CA    . GLY A 1 337 ? 129.180 114.576 130.805 1.00 64.49  ? 337 GLY A CA    1 
ATOM 1729 C C     . GLY A 1 337 ? 128.128 115.483 131.389 1.00 64.49  ? 337 GLY A C     1 
ATOM 1730 O O     . GLY A 1 337 ? 127.039 115.013 131.726 1.00 64.49  ? 337 GLY A O     1 
ATOM 1731 N N     . ASP A 1 338 ? 128.419 116.781 131.515 1.00 68.78  ? 338 ASP A N     1 
ATOM 1732 C CA    . ASP A 1 338 ? 127.506 117.763 132.095 1.00 68.78  ? 338 ASP A CA    1 
ATOM 1733 C C     . ASP A 1 338 ? 127.171 118.801 131.030 1.00 68.78  ? 338 ASP A C     1 
ATOM 1734 O O     . ASP A 1 338 ? 127.883 119.805 130.880 1.00 68.78  ? 338 ASP A O     1 
ATOM 1735 C CB    . ASP A 1 338 ? 128.115 118.432 133.328 1.00 68.78  ? 338 ASP A CB    1 
ATOM 1736 C CG    . ASP A 1 338 ? 128.478 117.441 134.417 1.00 68.78  ? 338 ASP A CG    1 
ATOM 1737 O OD1   . ASP A 1 338 ? 127.899 116.336 134.441 1.00 68.78  ? 338 ASP A OD1   1 
ATOM 1738 O OD2   . ASP A 1 338 ? 129.343 117.771 135.253 1.00 68.78  ? 338 ASP A OD2   1 
ATOM 1739 N N     . PRO A 1 339 ? 126.100 118.595 130.271 1.00 63.62  ? 339 PRO A N     1 
ATOM 1740 C CA    . PRO A 1 339 ? 125.689 119.596 129.283 1.00 63.62  ? 339 PRO A CA    1 
ATOM 1741 C C     . PRO A 1 339 ? 125.014 120.783 129.950 1.00 63.62  ? 339 PRO A C     1 
ATOM 1742 O O     . PRO A 1 339 ? 124.692 120.774 131.139 1.00 63.62  ? 339 PRO A O     1 
ATOM 1743 C CB    . PRO A 1 339 ? 124.716 118.828 128.389 1.00 63.62  ? 339 PRO A CB    1 
ATOM 1744 C CG    . PRO A 1 339 ? 124.144 117.795 129.286 1.00 63.62  ? 339 PRO A CG    1 
ATOM 1745 C CD    . PRO A 1 339 ? 125.258 117.389 130.212 1.00 63.62  ? 339 PRO A CD    1 
ATOM 1746 N N     . VAL A 1 340 ? 124.804 121.825 129.157 1.00 61.28  ? 340 VAL A N     1 
ATOM 1747 C CA    . VAL A 1 340 ? 124.111 123.033 129.600 1.00 61.28  ? 340 VAL A CA    1 
ATOM 1748 C C     . VAL A 1 340 ? 122.957 123.244 128.628 1.00 61.28  ? 340 VAL A C     1 
ATOM 1749 O O     . VAL A 1 340 ? 123.097 123.918 127.604 1.00 61.28  ? 340 VAL A O     1 
ATOM 1750 C CB    . VAL A 1 340 ? 125.031 124.254 129.649 1.00 61.28  ? 340 VAL A CB    1 
ATOM 1751 C CG1   . VAL A 1 340 ? 124.280 125.468 130.179 1.00 61.28  ? 340 VAL A CG1   1 
ATOM 1752 C CG2   . VAL A 1 340 ? 126.260 123.963 130.497 1.00 61.28  ? 340 VAL A CG2   1 
ATOM 1753 N N     . LEU A 1 341 ? 121.802 122.668 128.944 1.00 57.64  ? 341 LEU A N     1 
ATOM 1754 C CA    . LEU A 1 341 ? 120.653 122.793 128.061 1.00 57.64  ? 341 LEU A CA    1 
ATOM 1755 C C     . LEU A 1 341 ? 120.120 124.219 128.088 1.00 57.64  ? 341 LEU A C     1 
ATOM 1756 O O     . LEU A 1 341 ? 120.133 124.886 129.126 1.00 57.64  ? 341 LEU A O     1 
ATOM 1757 C CB    . LEU A 1 341 ? 119.555 121.814 128.469 1.00 57.64  ? 341 LEU A CB    1 
ATOM 1758 C CG    . LEU A 1 341 ? 119.966 120.367 128.733 1.00 57.64  ? 341 LEU A CG    1 
ATOM 1759 C CD1   . LEU A 1 341 ? 118.739 119.514 129.002 1.00 57.64  ? 341 LEU A CD1   1 
ATOM 1760 C CD2   . LEU A 1 341 ? 120.763 119.806 127.564 1.00 57.64  ? 341 LEU A CD2   1 
ATOM 1761 N N     . ASP A 1 342 ? 119.649 124.684 126.936 1.00 60.13  ? 342 ASP A N     1 
ATOM 1762 C CA    . ASP A 1 342 ? 119.064 126.019 126.812 1.00 60.13  ? 342 ASP A CA    1 
ATOM 1763 C C     . ASP A 1 342 ? 117.606 125.887 126.402 1.00 60.13  ? 342 ASP A C     1 
ATOM 1764 O O     . ASP A 1 342 ? 117.309 125.655 125.216 1.00 60.13  ? 342 ASP A O     1 
ATOM 1765 C CB    . ASP A 1 342 ? 119.834 126.862 125.798 1.00 60.13  ? 342 ASP A CB    1 
ATOM 1766 C CG    . ASP A 1 342 ? 119.579 128.344 125.965 1.00 60.13  ? 342 ASP A CG    1 
ATOM 1767 O OD1   . ASP A 1 342 ? 118.651 128.704 126.715 1.00 60.13  ? 342 ASP A OD1   1 
ATOM 1768 O OD2   . ASP A 1 342 ? 120.300 129.148 125.341 1.00 60.13  ? 342 ASP A OD2   1 
ATOM 1769 N N     . PRO A 1 343 ? 116.660 126.025 127.333 1.00 64.56  ? 343 PRO A N     1 
ATOM 1770 C CA    . PRO A 1 343 ? 115.242 125.947 126.965 1.00 64.56  ? 343 PRO A CA    1 
ATOM 1771 C C     . PRO A 1 343 ? 114.758 127.220 126.290 1.00 64.56  ? 343 PRO A C     1 
ATOM 1772 O O     . PRO A 1 343 ? 113.684 127.747 126.596 1.00 64.56  ? 343 PRO A O     1 
ATOM 1773 C CB    . PRO A 1 343 ? 114.543 125.713 128.309 1.00 64.56  ? 343 PRO A CB    1 
ATOM 1774 C CG    . PRO A 1 343 ? 115.451 126.322 129.302 1.00 64.56  ? 343 PRO A CG    1 
ATOM 1775 C CD    . PRO A 1 343 ? 116.847 126.093 128.789 1.00 64.56  ? 343 PRO A CD    1 
ATOM 1776 N N     . LYS A 1 344 ? 115.571 127.711 125.363 1.00 67.94  ? 344 LYS A N     1 
ATOM 1777 C CA    . LYS A 1 344 ? 115.237 128.727 124.377 1.00 67.94  ? 344 LYS A CA    1 
ATOM 1778 C C     . LYS A 1 344 ? 116.262 128.589 123.264 1.00 67.94  ? 344 LYS A C     1 
ATOM 1779 O O     . LYS A 1 344 ? 117.363 128.079 123.492 1.00 67.94  ? 344 LYS A O     1 
ATOM 1780 C CB    . LYS A 1 344 ? 115.247 130.142 124.967 1.00 67.94  ? 344 LYS A CB    1 
ATOM 1781 C CG    . LYS A 1 344 ? 116.612 130.642 125.399 1.00 67.94  ? 344 LYS A CG    1 
ATOM 1782 C CD    . LYS A 1 344 ? 116.514 132.007 126.063 1.00 67.94  ? 344 LYS A CD    1 
ATOM 1783 C CE    . LYS A 1 344 ? 116.192 133.093 125.051 1.00 67.94  ? 344 LYS A CE    1 
ATOM 1784 N NZ    . LYS A 1 344 ? 116.191 134.450 125.665 1.00 67.94  ? 344 LYS A NZ    1 
ATOM 1785 N N     . ARG A 1 345 ? 115.915 129.089 122.074 1.00 71.40  ? 345 ARG A N     1 
ATOM 1786 C CA    . ARG A 1 345 ? 116.793 128.992 120.895 1.00 71.40  ? 345 ARG A CA    1 
ATOM 1787 C C     . ARG A 1 345 ? 116.905 127.554 120.418 1.00 71.40  ? 345 ARG A C     1 
ATOM 1788 O O     . ARG A 1 345 ? 117.526 127.286 119.390 1.00 71.40  ? 345 ARG A O     1 
ATOM 1789 C CB    . ARG A 1 345 ? 118.159 129.661 121.112 1.00 71.40  ? 345 ARG A CB    1 
ATOM 1790 C CG    . ARG A 1 345 ? 118.063 131.154 121.383 1.00 71.40  ? 345 ARG A CG    1 
ATOM 1791 C CD    . ARG A 1 345 ? 119.395 131.738 121.819 1.00 71.40  ? 345 ARG A CD    1 
ATOM 1792 N NE    . ARG A 1 345 ? 120.466 131.423 120.880 1.00 71.40  ? 345 ARG A NE    1 
ATOM 1793 C CZ    . ARG A 1 345 ? 121.677 131.966 120.926 1.00 71.40  ? 345 ARG A CZ    1 
ATOM 1794 N NH1   . ARG A 1 345 ? 121.963 132.866 121.855 1.00 71.40  ? 345 ARG A NH1   1 
ATOM 1795 N NH2   . ARG A 1 345 ? 122.598 131.623 120.036 1.00 71.40  ? 345 ARG A NH2   1 
ATOM 1796 N N     . GLY A 1 346 ? 116.298 126.627 121.154 1.00 67.20  ? 346 GLY A N     1 
ATOM 1797 C CA    . GLY A 1 346 ? 116.294 125.232 120.742 1.00 67.20  ? 346 GLY A CA    1 
ATOM 1798 C C     . GLY A 1 346 ? 117.670 124.638 120.542 1.00 67.20  ? 346 GLY A C     1 
ATOM 1799 O O     . GLY A 1 346 ? 117.875 123.840 119.627 1.00 67.20  ? 346 GLY A O     1 
ATOM 1800 N N     . ILE A 1 347 ? 118.615 125.014 121.394 1.00 56.50  ? 347 ILE A N     1 
ATOM 1801 C CA    . ILE A 1 347 ? 119.979 124.523 121.255 1.00 56.50  ? 347 ILE A CA    1 
ATOM 1802 C C     . ILE A 1 347 ? 120.536 124.018 122.565 1.00 56.50  ? 347 ILE A C     1 
ATOM 1803 O O     . ILE A 1 347 ? 120.071 124.404 123.636 1.00 56.50  ? 347 ILE A O     1 
ATOM 1804 C CB    . ILE A 1 347 ? 120.943 125.605 120.721 1.00 56.50  ? 347 ILE A CB    1 
ATOM 1805 C CG1   . ILE A 1 347 ? 120.791 126.903 121.517 1.00 56.50  ? 347 ILE A CG1   1 
ATOM 1806 C CG2   . ILE A 1 347 ? 120.727 125.848 119.234 1.00 56.50  ? 347 ILE A CG2   1 
ATOM 1807 C CD1   . ILE A 1 347 ? 121.806 127.962 121.152 1.00 56.50  ? 347 ILE A CD1   1 
ATOM 1808 N N     . ALA A 1 348 ? 121.515 123.131 122.488 1.00 56.42  ? 348 ALA A N     1 
ATOM 1809 C CA    . ALA A 1 348 ? 122.171 122.652 123.691 1.00 56.42  ? 348 ALA A CA    1 
ATOM 1810 C C     . ALA A 1 348 ? 123.651 122.871 123.457 1.00 56.42  ? 348 ALA A C     1 
ATOM 1811 O O     . ALA A 1 348 ? 124.081 123.010 122.314 1.00 56.42  ? 348 ALA A O     1 
ATOM 1812 C CB    . ALA A 1 348 ? 121.867 121.185 123.929 1.00 56.42  ? 348 ALA A CB    1 
ATOM 1813 N N     . THR A 1 349 ? 124.434 122.914 124.524 1.00 60.12  ? 349 THR A N     1 
ATOM 1814 C CA    . THR A 1 349 ? 125.862 123.176 124.401 1.00 60.12  ? 349 THR A CA    1 
ATOM 1815 C C     . THR A 1 349 ? 126.649 122.199 125.265 1.00 60.12  ? 349 THR A C     1 
ATOM 1816 O O     . THR A 1 349 ? 126.332 122.013 126.445 1.00 60.12  ? 349 THR A O     1 
ATOM 1817 C CB    . THR A 1 349 ? 126.190 124.616 124.804 1.00 60.12  ? 349 THR A CB    1 
ATOM 1818 O OG1   . THR A 1 349 ? 125.793 125.511 123.758 1.00 60.12  ? 349 THR A OG1   1 
ATOM 1819 C CG2   . THR A 1 349 ? 127.676 124.781 125.072 1.00 60.12  ? 349 THR A CG2   1 
ATOM 1820 N N     . PHE A 1 350 ? 127.668 121.581 124.676 1.00 62.97  ? 350 PHE A N     1 
ATOM 1821 C CA    . PHE A 1 350 ? 128.568 120.674 125.374 1.00 62.97  ? 350 PHE A CA    1 
ATOM 1822 C C     . PHE A 1 350 ? 129.947 121.297 125.529 1.00 62.97  ? 350 PHE A C     1 
ATOM 1823 O O     . PHE A 1 350 ? 130.261 122.343 124.956 1.00 62.97  ? 350 PHE A O     1 
ATOM 1824 C CB    . PHE A 1 350 ? 128.693 119.341 124.635 1.00 62.97  ? 350 PHE A CB    1 
ATOM 1825 C CG    . PHE A 1 350 ? 127.555 118.410 124.870 1.00 62.97  ? 350 PHE A CG    1 
ATOM 1826 C CD1   . PHE A 1 350 ? 126.315 118.655 124.316 1.00 62.97  ? 350 PHE A CD1   1 
ATOM 1827 C CD2   . PHE A 1 350 ? 127.728 117.279 125.640 1.00 62.97  ? 350 PHE A CD2   1 
ATOM 1828 C CE1   . PHE A 1 350 ? 125.268 117.788 124.532 1.00 62.97  ? 350 PHE A CE1   1 
ATOM 1829 C CE2   . PHE A 1 350 ? 126.686 116.411 125.858 1.00 62.97  ? 350 PHE A CE2   1 
ATOM 1830 C CZ    . PHE A 1 350 ? 125.455 116.665 125.305 1.00 62.97  ? 350 PHE A CZ    1 
ATOM 1831 N N     . THR A 1 351 ? 130.774 120.623 126.321 1.00 73.08  ? 351 THR A N     1 
ATOM 1832 C CA    . THR A 1 351 ? 132.181 120.955 126.465 1.00 73.08  ? 351 THR A CA    1 
ATOM 1833 C C     . THR A 1 351 ? 132.997 119.673 126.405 1.00 73.08  ? 351 THR A C     1 
ATOM 1834 O O     . THR A 1 351 ? 132.511 118.594 126.753 1.00 73.08  ? 351 THR A O     1 
ATOM 1835 C CB    . THR A 1 351 ? 132.463 121.694 127.779 1.00 73.08  ? 351 THR A CB    1 
ATOM 1836 O OG1   . THR A 1 351 ? 131.746 121.063 128.847 1.00 73.08  ? 351 THR A OG1   1 
ATOM 1837 C CG2   . THR A 1 351 ? 132.033 123.149 127.676 1.00 73.08  ? 351 THR A CG2   1 
ATOM 1838 N N     . PHE A 1 352 ? 134.240 119.797 125.952 1.00 70.57  ? 352 PHE A N     1 
ATOM 1839 C CA    . PHE A 1 352 ? 135.127 118.647 125.838 1.00 70.57  ? 352 PHE A CA    1 
ATOM 1840 C C     . PHE A 1 352 ? 135.774 118.366 127.193 1.00 70.57  ? 352 PHE A C     1 
ATOM 1841 O O     . PHE A 1 352 ? 135.403 118.935 128.222 1.00 70.57  ? 352 PHE A O     1 
ATOM 1842 C CB    . PHE A 1 352 ? 136.180 118.888 124.760 1.00 70.57  ? 352 PHE A CB    1 
ATOM 1843 C CG    . PHE A 1 352 ? 135.646 118.840 123.355 1.00 70.57  ? 352 PHE A CG    1 
ATOM 1844 C CD1   . PHE A 1 352 ? 134.810 119.835 122.879 1.00 70.57  ? 352 PHE A CD1   1 
ATOM 1845 C CD2   . PHE A 1 352 ? 135.996 117.806 122.506 1.00 70.57  ? 352 PHE A CD2   1 
ATOM 1846 C CE1   . PHE A 1 352 ? 134.327 119.793 121.588 1.00 70.57  ? 352 PHE A CE1   1 
ATOM 1847 C CE2   . PHE A 1 352 ? 135.516 117.760 121.216 1.00 70.57  ? 352 PHE A CE2   1 
ATOM 1848 C CZ    . PHE A 1 352 ? 134.683 118.755 120.755 1.00 70.57  ? 352 PHE A CZ    1 
ATOM 1849 N N     . LYS A 1 353 ? 136.757 117.474 127.199 1.00 68.37  ? 353 LYS A N     1 
ATOM 1850 C CA    . LYS A 1 353 ? 137.589 117.211 128.358 1.00 68.37  ? 353 LYS A CA    1 
ATOM 1851 C C     . LYS A 1 353 ? 138.928 117.924 128.183 1.00 68.37  ? 353 LYS A C     1 
ATOM 1852 O O     . LYS A 1 353 ? 139.104 118.751 127.283 1.00 68.37  ? 353 LYS A O     1 
ATOM 1853 C CB    . LYS A 1 353 ? 137.761 115.705 128.556 1.00 68.37  ? 353 LYS A CB    1 
ATOM 1854 C CG    . LYS A 1 353 ? 136.522 115.012 129.087 1.00 68.37  ? 353 LYS A CG    1 
ATOM 1855 C CD    . LYS A 1 353 ? 136.840 113.613 129.577 1.00 68.37  ? 353 LYS A CD    1 
ATOM 1856 C CE    . LYS A 1 353 ? 135.570 112.823 129.841 1.00 68.37  ? 353 LYS A CE    1 
ATOM 1857 N NZ    . LYS A 1 353 ? 135.798 111.707 130.795 1.00 68.37  ? 353 LYS A NZ    1 
ATOM 1858 N N     . LEU A 1 354 ? 139.886 117.614 129.059 1.00 72.40  ? 354 LEU A N     1 
ATOM 1859 C CA    . LEU A 1 354 ? 141.194 118.258 128.993 1.00 72.40  ? 354 LEU A CA    1 
ATOM 1860 C C     . LEU A 1 354 ? 141.938 117.945 127.700 1.00 72.40  ? 354 LEU A C     1 
ATOM 1861 O O     . LEU A 1 354 ? 142.859 118.685 127.336 1.00 72.40  ? 354 LEU A O     1 
ATOM 1862 C CB    . LEU A 1 354 ? 142.048 117.843 130.194 1.00 72.40  ? 354 LEU A CB    1 
ATOM 1863 C CG    . LEU A 1 354 ? 141.935 118.677 131.475 1.00 72.40  ? 354 LEU A CG    1 
ATOM 1864 C CD1   . LEU A 1 354 ? 142.366 120.116 131.220 1.00 72.40  ? 354 LEU A CD1   1 
ATOM 1865 C CD2   . LEU A 1 354 ? 140.531 118.627 132.066 1.00 72.40  ? 354 LEU A CD2   1 
ATOM 1866 N N     . GLY A 1 355 ? 141.566 116.877 127.000 1.00 66.08  ? 355 GLY A N     1 
ATOM 1867 C CA    . GLY A 1 355 ? 142.222 116.512 125.757 1.00 66.08  ? 355 GLY A CA    1 
ATOM 1868 C C     . GLY A 1 355 ? 141.843 117.393 124.581 1.00 66.08  ? 355 GLY A C     1 
ATOM 1869 O O     . GLY A 1 355 ? 142.201 117.110 123.437 1.00 66.08  ? 355 GLY A O     1 
ATOM 1870 P P     . C   B 2 5   ? 149.143 113.913 104.743 1.00 90.19  ? -21 C   B P     1 
ATOM 1871 O OP1   . C   B 2 5   ? 149.161 113.903 103.258 1.00 90.19  ? -21 C   B OP1   1 
ATOM 1872 O OP2   . C   B 2 5   ? 150.425 113.936 105.493 1.00 90.19  ? -21 C   B OP2   1 
ATOM 1873 O "O5'" . C   B 2 5   ? 148.312 112.646 105.235 1.00 90.19  ? -21 C   B "O5'" 1 
ATOM 1874 C "C5'" . C   B 2 5   ? 146.960 112.463 104.844 1.00 90.19  ? -21 C   B "C5'" 1 
ATOM 1875 C "C4'" . C   B 2 5   ? 146.311 111.345 105.618 1.00 90.19  ? -21 C   B "C4'" 1 
ATOM 1876 O "O4'" . C   B 2 5   ? 146.478 111.576 107.042 1.00 90.19  ? -21 C   B "O4'" 1 
ATOM 1877 C "C3'" . C   B 2 5   ? 144.808 111.194 105.438 1.00 90.19  ? -21 C   B "C3'" 1 
ATOM 1878 O "O3'" . C   B 2 5   ? 144.466 110.471 104.267 1.00 90.19  ? -21 C   B "O3'" 1 
ATOM 1879 C "C2'" . C   B 2 5   ? 144.385 110.498 106.723 1.00 90.19  ? -21 C   B "C2'" 1 
ATOM 1880 O "O2'" . C   B 2 5   ? 144.661 109.107 106.653 1.00 90.19  ? -21 C   B "O2'" 1 
ATOM 1881 C "C1'" . C   B 2 5   ? 145.336 111.129 107.742 1.00 90.19  ? -21 C   B "C1'" 1 
ATOM 1882 N N1    . C   B 2 5   ? 144.731 112.287 108.440 1.00 90.19  ? -21 C   B N1    1 
ATOM 1883 C C2    . C   B 2 5   ? 143.670 112.099 109.335 1.00 90.19  ? -21 C   B C2    1 
ATOM 1884 O O2    . C   B 2 5   ? 143.224 110.960 109.536 1.00 90.19  ? -21 C   B O2    1 
ATOM 1885 N N3    . C   B 2 5   ? 143.137 113.171 109.961 1.00 90.19  ? -21 C   B N3    1 
ATOM 1886 C C4    . C   B 2 5   ? 143.626 114.390 109.736 1.00 90.19  ? -21 C   B C4    1 
ATOM 1887 N N4    . C   B 2 5   ? 143.068 115.418 110.380 1.00 90.19  ? -21 C   B N4    1 
ATOM 1888 C C5    . C   B 2 5   ? 144.710 114.612 108.840 1.00 90.19  ? -21 C   B C5    1 
ATOM 1889 C C6    . C   B 2 5   ? 145.226 113.542 108.223 1.00 90.19  ? -21 C   B C6    1 
ATOM 1890 P P     . G   B 2 6   ? 142.999 110.606 103.626 1.00 89.63  ? -20 G   B P     1 
ATOM 1891 O OP1   . G   B 2 6   ? 142.949 109.739 102.423 1.00 89.63  ? -20 G   B OP1   1 
ATOM 1892 O OP2   . G   B 2 6   ? 142.676 112.050 103.508 1.00 89.63  ? -20 G   B OP2   1 
ATOM 1893 O "O5'" . G   B 2 6   ? 142.031 109.974 104.723 1.00 89.63  ? -20 G   B "O5'" 1 
ATOM 1894 C "C5'" . G   B 2 6   ? 140.635 110.237 104.702 1.00 89.63  ? -20 G   B "C5'" 1 
ATOM 1895 C "C4'" . G   B 2 6   ? 140.103 110.509 106.088 1.00 89.63  ? -20 G   B "C4'" 1 
ATOM 1896 O "O4'" . G   B 2 6   ? 141.140 111.123 106.896 1.00 89.63  ? -20 G   B "O4'" 1 
ATOM 1897 C "C3'" . G   B 2 6   ? 138.933 111.480 106.169 1.00 89.63  ? -20 G   B "C3'" 1 
ATOM 1898 O "O3'" . G   B 2 6   ? 137.686 110.852 105.926 1.00 89.63  ? -20 G   B "O3'" 1 
ATOM 1899 C "C2'" . G   B 2 6   ? 139.059 112.053 107.575 1.00 89.63  ? -20 G   B "C2'" 1 
ATOM 1900 O "O2'" . G   B 2 6   ? 138.507 111.161 108.532 1.00 89.63  ? -20 G   B "O2'" 1 
ATOM 1901 C "C1'" . G   B 2 6   ? 140.577 112.083 107.763 1.00 89.63  ? -20 G   B "C1'" 1 
ATOM 1902 N N9    . G   B 2 6   ? 141.174 113.396 107.448 1.00 89.63  ? -20 G   B N9    1 
ATOM 1903 C C8    . G   B 2 6   ? 142.250 113.595 106.617 1.00 89.63  ? -20 G   B C8    1 
ATOM 1904 N N7    . G   B 2 6   ? 142.595 114.845 106.507 1.00 89.63  ? -20 G   B N7    1 
ATOM 1905 C C5    . G   B 2 6   ? 141.705 115.518 107.328 1.00 89.63  ? -20 G   B C5    1 
ATOM 1906 C C6    . G   B 2 6   ? 141.600 116.903 107.610 1.00 89.63  ? -20 G   B C6    1 
ATOM 1907 O O6    . G   B 2 6   ? 142.293 117.833 107.178 1.00 89.63  ? -20 G   B O6    1 
ATOM 1908 N N1    . G   B 2 6   ? 140.561 117.167 108.494 1.00 89.63  ? -20 G   B N1    1 
ATOM 1909 C C2    . G   B 2 6   ? 139.732 116.219 109.036 1.00 89.63  ? -20 G   B C2    1 
ATOM 1910 N N2    . G   B 2 6   ? 138.786 116.674 109.868 1.00 89.63  ? -20 G   B N2    1 
ATOM 1911 N N3    . G   B 2 6   ? 139.819 114.923 108.781 1.00 89.63  ? -20 G   B N3    1 
ATOM 1912 C C4    . G   B 2 6   ? 140.822 114.641 107.924 1.00 89.63  ? -20 G   B C4    1 
ATOM 1913 P P     . C   B 2 7   ? 136.574 111.562 105.009 1.00 77.26  ? -19 C   B P     1 
ATOM 1914 O OP1   . C   B 2 7   ? 135.569 110.531 104.650 1.00 77.26  ? -19 C   B OP1   1 
ATOM 1915 O OP2   . C   B 2 7   ? 137.273 112.300 103.928 1.00 77.26  ? -19 C   B OP2   1 
ATOM 1916 O "O5'" . C   B 2 7   ? 135.882 112.621 105.981 1.00 77.26  ? -19 C   B "O5'" 1 
ATOM 1917 C "C5'" . C   B 2 7   ? 135.420 112.229 107.270 1.00 77.26  ? -19 C   B "C5'" 1 
ATOM 1918 C "C4'" . C   B 2 7   ? 134.375 113.170 107.827 1.00 77.26  ? -19 C   B "C4'" 1 
ATOM 1919 O "O4'" . C   B 2 7   ? 135.009 114.383 108.320 1.00 77.26  ? -19 C   B "O4'" 1 
ATOM 1920 C "C3'" . C   B 2 7   ? 133.289 113.623 106.853 1.00 77.26  ? -19 C   B "C3'" 1 
ATOM 1921 O "O3'" . C   B 2 7   ? 132.055 113.733 107.555 1.00 77.26  ? -19 C   B "O3'" 1 
ATOM 1922 C "C2'" . C   B 2 7   ? 133.758 115.015 106.450 1.00 77.26  ? -19 C   B "C2'" 1 
ATOM 1923 O "O2'" . C   B 2 7   ? 132.731 115.873 105.999 1.00 77.26  ? -19 C   B "O2'" 1 
ATOM 1924 C "C1'" . C   B 2 7   ? 134.375 115.510 107.750 1.00 77.26  ? -19 C   B "C1'" 1 
ATOM 1925 N N1    . C   B 2 7   ? 135.372 116.571 107.579 1.00 77.26  ? -19 C   B N1    1 
ATOM 1926 C C2    . C   B 2 7   ? 135.072 117.847 108.051 1.00 77.26  ? -19 C   B C2    1 
ATOM 1927 O O2    . C   B 2 7   ? 133.973 118.040 108.590 1.00 77.26  ? -19 C   B O2    1 
ATOM 1928 N N3    . C   B 2 7   ? 135.977 118.837 107.907 1.00 77.26  ? -19 C   B N3    1 
ATOM 1929 C C4    . C   B 2 7   ? 137.146 118.584 107.321 1.00 77.26  ? -19 C   B C4    1 
ATOM 1930 N N4    . C   B 2 7   ? 138.015 119.590 107.198 1.00 77.26  ? -19 C   B N4    1 
ATOM 1931 C C5    . C   B 2 7   ? 137.478 117.289 106.835 1.00 77.26  ? -19 C   B C5    1 
ATOM 1932 C C6    . C   B 2 7   ? 136.570 116.319 106.984 1.00 77.26  ? -19 C   B C6    1 
ATOM 1933 P P     . U   B 2 8   ? 130.943 112.585 107.413 1.00 64.16  ? -18 U   B P     1 
ATOM 1934 O OP1   . U   B 2 8   ? 130.593 112.100 108.768 1.00 64.16  ? -18 U   B OP1   1 
ATOM 1935 O OP2   . U   B 2 8   ? 131.412 111.619 106.389 1.00 64.16  ? -18 U   B OP2   1 
ATOM 1936 O "O5'" . U   B 2 8   ? 129.680 113.356 106.834 1.00 64.16  ? -18 U   B "O5'" 1 
ATOM 1937 C "C5'" . U   B 2 8   ? 129.060 114.397 107.579 1.00 64.16  ? -18 U   B "C5'" 1 
ATOM 1938 C "C4'" . U   B 2 8   ? 127.640 114.622 107.130 1.00 64.16  ? -18 U   B "C4'" 1 
ATOM 1939 O "O4'" . U   B 2 8   ? 126.921 113.362 107.203 1.00 64.16  ? -18 U   B "O4'" 1 
ATOM 1940 C "C3'" . U   B 2 8   ? 126.842 115.615 107.971 1.00 64.16  ? -18 U   B "C3'" 1 
ATOM 1941 O "O3'" . U   B 2 8   ? 125.889 116.275 107.138 1.00 64.16  ? -18 U   B "O3'" 1 
ATOM 1942 C "C2'" . U   B 2 8   ? 126.110 114.702 108.946 1.00 64.16  ? -18 U   B "C2'" 1 
ATOM 1943 O "O2'" . U   B 2 8   ? 124.935 115.259 109.496 1.00 64.16  ? -18 U   B "O2'" 1 
ATOM 1944 C "C1'" . U   B 2 8   ? 125.806 113.499 108.059 1.00 64.16  ? -18 U   B "C1'" 1 
ATOM 1945 N N1    . U   B 2 8   ? 125.630 112.239 108.790 1.00 64.16  ? -18 U   B N1    1 
ATOM 1946 C C2    . U   B 2 8   ? 124.361 111.707 108.836 1.00 64.16  ? -18 U   B C2    1 
ATOM 1947 O O2    . U   B 2 8   ? 123.404 112.243 108.306 1.00 64.16  ? -18 U   B O2    1 
ATOM 1948 N N3    . U   B 2 8   ? 124.251 110.531 109.528 1.00 64.16  ? -18 U   B N3    1 
ATOM 1949 C C4    . U   B 2 8   ? 125.261 109.845 110.162 1.00 64.16  ? -18 U   B C4    1 
ATOM 1950 O O4    . U   B 2 8   ? 125.002 108.792 110.744 1.00 64.16  ? -18 U   B O4    1 
ATOM 1951 C C5    . U   B 2 8   ? 126.547 110.459 110.065 1.00 64.16  ? -18 U   B C5    1 
ATOM 1952 C C6    . U   B 2 8   ? 126.684 111.606 109.397 1.00 64.16  ? -18 U   B C6    1 
ATOM 1953 P P     . U   B 2 9   ? 125.787 117.879 107.118 1.00 67.02  ? -17 U   B P     1 
ATOM 1954 O OP1   . U   B 2 9   ? 125.243 118.288 105.800 1.00 67.02  ? -17 U   B OP1   1 
ATOM 1955 O OP2   . U   B 2 9   ? 127.073 118.440 107.587 1.00 67.02  ? -17 U   B OP2   1 
ATOM 1956 O "O5'" . U   B 2 9   ? 124.696 118.212 108.224 1.00 67.02  ? -17 U   B "O5'" 1 
ATOM 1957 C "C5'" . U   B 2 9   ? 123.364 117.742 108.104 1.00 67.02  ? -17 U   B "C5'" 1 
ATOM 1958 C "C4'" . U   B 2 9   ? 122.602 117.930 109.390 1.00 67.02  ? -17 U   B "C4'" 1 
ATOM 1959 O "O4'" . U   B 2 9   ? 123.391 117.418 110.499 1.00 67.02  ? -17 U   B "O4'" 1 
ATOM 1960 C "C3'" . U   B 2 9   ? 122.312 119.366 109.789 1.00 67.02  ? -17 U   B "C3'" 1 
ATOM 1961 O "O3'" . U   B 2 9   ? 121.207 119.938 109.113 1.00 67.02  ? -17 U   B "O3'" 1 
ATOM 1962 C "C2'" . U   B 2 9   ? 122.121 119.250 111.292 1.00 67.02  ? -17 U   B "C2'" 1 
ATOM 1963 O "O2'" . U   B 2 9   ? 120.856 118.680 111.594 1.00 67.02  ? -17 U   B "O2'" 1 
ATOM 1964 C "C1'" . U   B 2 9   ? 123.202 118.233 111.639 1.00 67.02  ? -17 U   B "C1'" 1 
ATOM 1965 N N1    . U   B 2 9   ? 124.483 118.904 111.951 1.00 67.02  ? -17 U   B N1    1 
ATOM 1966 C C2    . U   B 2 9   ? 124.589 119.589 113.142 1.00 67.02  ? -17 U   B C2    1 
ATOM 1967 O O2    . U   B 2 9   ? 123.684 119.663 113.956 1.00 67.02  ? -17 U   B O2    1 
ATOM 1968 N N3    . U   B 2 9   ? 125.800 120.192 113.357 1.00 67.02  ? -17 U   B N3    1 
ATOM 1969 C C4    . U   B 2 9   ? 126.896 120.184 112.524 1.00 67.02  ? -17 U   B C4    1 
ATOM 1970 O O4    . U   B 2 9   ? 127.920 120.777 112.860 1.00 67.02  ? -17 U   B O4    1 
ATOM 1971 C C5    . U   B 2 9   ? 126.710 119.456 111.311 1.00 67.02  ? -17 U   B C5    1 
ATOM 1972 C C6    . U   B 2 9   ? 125.540 118.860 111.076 1.00 67.02  ? -17 U   B C6    1 
ATOM 1973 P P     . G   B 2 10  ? 121.302 121.442 108.554 1.00 72.72  ? -16 G   B P     1 
ATOM 1974 O OP1   . G   B 2 10  ? 119.917 121.933 108.347 1.00 72.72  ? -16 G   B OP1   1 
ATOM 1975 O OP2   . G   B 2 10  ? 122.260 121.454 107.422 1.00 72.72  ? -16 G   B OP2   1 
ATOM 1976 O "O5'" . G   B 2 10  ? 121.946 122.276 109.751 1.00 72.72  ? -16 G   B "O5'" 1 
ATOM 1977 C "C5'" . G   B 2 10  ? 121.188 122.584 110.911 1.00 72.72  ? -16 G   B "C5'" 1 
ATOM 1978 C "C4'" . G   B 2 10  ? 121.785 123.718 111.708 1.00 72.72  ? -16 G   B "C4'" 1 
ATOM 1979 O "O4'" . G   B 2 10  ? 123.091 123.364 112.226 1.00 72.72  ? -16 G   B "O4'" 1 
ATOM 1980 C "C3'" . G   B 2 10  ? 122.046 125.014 110.967 1.00 72.72  ? -16 G   B "C3'" 1 
ATOM 1981 O "O3'" . G   B 2 10  ? 120.870 125.763 110.721 1.00 72.72  ? -16 G   B "O3'" 1 
ATOM 1982 C "C2'" . G   B 2 10  ? 123.034 125.721 111.888 1.00 72.72  ? -16 G   B "C2'" 1 
ATOM 1983 O "O2'" . G   B 2 10  ? 122.355 126.338 112.972 1.00 72.72  ? -16 G   B "O2'" 1 
ATOM 1984 C "C1'" . G   B 2 10  ? 123.845 124.543 112.433 1.00 72.72  ? -16 G   B "C1'" 1 
ATOM 1985 N N9    . G   B 2 10  ? 125.175 124.431 111.805 1.00 72.72  ? -16 G   B N9    1 
ATOM 1986 C C8    . G   B 2 10  ? 125.645 123.482 110.936 1.00 72.72  ? -16 G   B C8    1 
ATOM 1987 N N7    . G   B 2 10  ? 126.887 123.689 110.586 1.00 72.72  ? -16 G   B N7    1 
ATOM 1988 C C5    . G   B 2 10  ? 127.265 124.837 111.265 1.00 72.72  ? -16 G   B C5    1 
ATOM 1989 C C6    . G   B 2 10  ? 128.494 125.549 111.280 1.00 72.72  ? -16 G   B C6    1 
ATOM 1990 O O6    . G   B 2 10  ? 129.538 125.287 110.675 1.00 72.72  ? -16 G   B O6    1 
ATOM 1991 N N1    . G   B 2 10  ? 128.452 126.664 112.105 1.00 72.72  ? -16 G   B N1    1 
ATOM 1992 C C2    . G   B 2 10  ? 127.348 127.044 112.826 1.00 72.72  ? -16 G   B C2    1 
ATOM 1993 N N2    . G   B 2 10  ? 127.482 128.152 113.570 1.00 72.72  ? -16 G   B N2    1 
ATOM 1994 N N3    . G   B 2 10  ? 126.193 126.394 112.818 1.00 72.72  ? -16 G   B N3    1 
ATOM 1995 C C4    . G   B 2 10  ? 126.219 125.304 112.021 1.00 72.72  ? -16 G   B C4    1 
ATOM 1996 P P     . C   B 2 11  ? 120.735 126.601 109.359 1.00 78.61  ? -15 C   B P     1 
ATOM 1997 O OP1   . C   B 2 11  ? 119.400 127.248 109.348 1.00 78.61  ? -15 C   B OP1   1 
ATOM 1998 O OP2   . C   B 2 11  ? 121.149 125.713 108.246 1.00 78.61  ? -15 C   B OP2   1 
ATOM 1999 O "O5'" . C   B 2 11  ? 121.859 127.725 109.479 1.00 78.61  ? -15 C   B "O5'" 1 
ATOM 2000 C "C5'" . C   B 2 11  ? 121.836 128.666 110.538 1.00 78.61  ? -15 C   B "C5'" 1 
ATOM 2001 C "C4'" . C   B 2 11  ? 123.147 129.403 110.671 1.00 78.61  ? -15 C   B "C4'" 1 
ATOM 2002 O "O4'" . C   B 2 11  ? 124.242 128.482 110.906 1.00 78.61  ? -15 C   B "O4'" 1 
ATOM 2003 C "C3'" . C   B 2 11  ? 123.607 130.199 109.466 1.00 78.61  ? -15 C   B "C3'" 1 
ATOM 2004 O "O3'" . C   B 2 11  ? 122.913 131.423 109.315 1.00 78.61  ? -15 C   B "O3'" 1 
ATOM 2005 C "C2'" . C   B 2 11  ? 125.094 130.378 109.745 1.00 78.61  ? -15 C   B "C2'" 1 
ATOM 2006 O "O2'" . C   B 2 11  ? 125.305 131.425 110.680 1.00 78.61  ? -15 C   B "O2'" 1 
ATOM 2007 C "C1'" . C   B 2 11  ? 125.445 129.049 110.424 1.00 78.61  ? -15 C   B "C1'" 1 
ATOM 2008 N N1    . C   B 2 11  ? 126.121 128.095 109.510 1.00 78.61  ? -15 C   B N1    1 
ATOM 2009 C C2    . C   B 2 11  ? 127.401 128.401 109.016 1.00 78.61  ? -15 C   B C2    1 
ATOM 2010 O O2    . C   B 2 11  ? 127.943 129.470 109.345 1.00 78.61  ? -15 C   B O2    1 
ATOM 2011 N N3    . C   B 2 11  ? 128.020 127.529 108.183 1.00 78.61  ? -15 C   B N3    1 
ATOM 2012 C C4    . C   B 2 11  ? 127.418 126.386 107.848 1.00 78.61  ? -15 C   B C4    1 
ATOM 2013 N N4    . C   B 2 11  ? 128.068 125.558 107.024 1.00 78.61  ? -15 C   B N4    1 
ATOM 2014 C C5    . C   B 2 11  ? 126.124 126.047 108.339 1.00 78.61  ? -15 C   B C5    1 
ATOM 2015 C C6    . C   B 2 11  ? 125.521 126.919 109.160 1.00 78.61  ? -15 C   B C6    1 
ATOM 2016 P P     . U   B 2 12  ? 122.761 132.088 107.862 1.00 89.94  ? -14 U   B P     1 
ATOM 2017 O OP1   . U   B 2 12  ? 121.855 133.258 107.985 1.00 89.94  ? -14 U   B OP1   1 
ATOM 2018 O OP2   . U   B 2 12  ? 122.436 131.010 106.895 1.00 89.94  ? -14 U   B OP2   1 
ATOM 2019 O "O5'" . U   B 2 12  ? 124.221 132.630 107.530 1.00 89.94  ? -14 U   B "O5'" 1 
ATOM 2020 C "C5'" . U   B 2 12  ? 124.778 133.718 108.252 1.00 89.94  ? -14 U   B "C5'" 1 
ATOM 2021 C "C4'" . U   B 2 12  ? 126.040 134.225 107.599 1.00 89.94  ? -14 U   B "C4'" 1 
ATOM 2022 O "O4'" . U   B 2 12  ? 127.112 133.268 107.791 1.00 89.94  ? -14 U   B "O4'" 1 
ATOM 2023 C "C3'" . U   B 2 12  ? 125.976 134.416 106.092 1.00 89.94  ? -14 U   B "C3'" 1 
ATOM 2024 O "O3'" . U   B 2 12  ? 125.380 135.646 105.722 1.00 89.94  ? -14 U   B "O3'" 1 
ATOM 2025 C "C2'" . U   B 2 12  ? 127.435 134.299 105.676 1.00 89.94  ? -14 U   B "C2'" 1 
ATOM 2026 O "O2'" . U   B 2 12  ? 128.126 135.514 105.926 1.00 89.94  ? -14 U   B "O2'" 1 
ATOM 2027 C "C1'" . U   B 2 12  ? 127.949 133.244 106.655 1.00 89.94  ? -14 U   B "C1'" 1 
ATOM 2028 N N1    . U   B 2 12  ? 127.936 131.874 106.090 1.00 89.94  ? -14 U   B N1    1 
ATOM 2029 C C2    . U   B 2 12  ? 128.931 131.510 105.200 1.00 89.94  ? -14 U   B C2    1 
ATOM 2030 O O2    . U   B 2 12  ? 129.812 132.271 104.839 1.00 89.94  ? -14 U   B O2    1 
ATOM 2031 N N3    . U   B 2 12  ? 128.851 130.218 104.735 1.00 89.94  ? -14 U   B N3    1 
ATOM 2032 C C4    . U   B 2 12  ? 127.898 129.275 105.073 1.00 89.94  ? -14 U   B C4    1 
ATOM 2033 O O4    . U   B 2 12  ? 127.943 128.146 104.583 1.00 89.94  ? -14 U   B O4    1 
ATOM 2034 C C5    . U   B 2 12  ? 126.913 129.728 106.003 1.00 89.94  ? -14 U   B C5    1 
ATOM 2035 C C6    . U   B 2 12  ? 126.968 130.977 106.468 1.00 89.94  ? -14 U   B C6    1 
ATOM 2036 P P     . C   B 2 13  ? 124.545 135.764 104.355 1.00 94.10  ? -13 C   B P     1 
ATOM 2037 O OP1   . C   B 2 13  ? 123.966 137.131 104.290 1.00 94.10  ? -13 C   B OP1   1 
ATOM 2038 O OP2   . C   B 2 13  ? 123.647 134.586 104.260 1.00 94.10  ? -13 C   B OP2   1 
ATOM 2039 O "O5'" . C   B 2 13  ? 125.653 135.650 103.217 1.00 94.10  ? -13 C   B "O5'" 1 
ATOM 2040 C "C5'" . C   B 2 13  ? 126.672 136.632 103.091 1.00 94.10  ? -13 C   B "C5'" 1 
ATOM 2041 C "C4'" . C   B 2 13  ? 127.740 136.198 102.118 1.00 94.10  ? -13 C   B "C4'" 1 
ATOM 2042 O "O4'" . C   B 2 13  ? 128.425 135.024 102.626 1.00 94.10  ? -13 C   B "O4'" 1 
ATOM 2043 C "C3'" . C   B 2 13  ? 127.250 135.775 100.743 1.00 94.10  ? -13 C   B "C3'" 1 
ATOM 2044 O "O3'" . C   B 2 13  ? 127.002 136.878 99.889  1.00 94.10  ? -13 C   B "O3'" 1 
ATOM 2045 C "C2'" . C   B 2 13  ? 128.364 134.859 100.255 1.00 94.10  ? -13 C   B "C2'" 1 
ATOM 2046 O "O2'" . C   B 2 13  ? 129.462 135.617 99.769  1.00 94.10  ? -13 C   B "O2'" 1 
ATOM 2047 C "C1'" . C   B 2 13  ? 128.788 134.175 101.557 1.00 94.10  ? -13 C   B "C1'" 1 
ATOM 2048 N N1    . C   B 2 13  ? 128.124 132.865 101.749 1.00 94.10  ? -13 C   B N1    1 
ATOM 2049 C C2    . C   B 2 13  ? 128.611 131.743 101.075 1.00 94.10  ? -13 C   B C2    1 
ATOM 2050 O O2    . C   B 2 13  ? 129.588 131.868 100.324 1.00 94.10  ? -13 C   B O2    1 
ATOM 2051 N N3    . C   B 2 13  ? 128.004 130.549 101.256 1.00 94.10  ? -13 C   B N3    1 
ATOM 2052 C C4    . C   B 2 13  ? 126.953 130.450 102.072 1.00 94.10  ? -13 C   B C4    1 
ATOM 2053 N N4    . C   B 2 13  ? 126.382 129.253 102.223 1.00 94.10  ? -13 C   B N4    1 
ATOM 2054 C C5    . C   B 2 13  ? 126.439 131.576 102.773 1.00 94.10  ? -13 C   B C5    1 
ATOM 2055 C C6    . C   B 2 13  ? 127.049 132.749 102.582 1.00 94.10  ? -13 C   B C6    1 
ATOM 2056 P P     . G   B 2 14  ? 126.001 136.727 98.644  1.00 93.83  ? -12 G   B P     1 
ATOM 2057 O OP1   . G   B 2 14  ? 125.590 138.088 98.216  1.00 93.83  ? -12 G   B OP1   1 
ATOM 2058 O OP2   . G   B 2 14  ? 124.963 135.726 99.001  1.00 93.83  ? -12 G   B OP2   1 
ATOM 2059 O "O5'" . G   B 2 14  ? 126.913 136.105 97.496  1.00 93.83  ? -12 G   B "O5'" 1 
ATOM 2060 C "C5'" . G   B 2 14  ? 126.347 135.707 96.258  1.00 93.83  ? -12 G   B "C5'" 1 
ATOM 2061 C "C4'" . G   B 2 14  ? 127.349 134.987 95.392  1.00 93.83  ? -12 G   B "C4'" 1 
ATOM 2062 O "O4'" . G   B 2 14  ? 128.124 134.063 96.198  1.00 93.83  ? -12 G   B "O4'" 1 
ATOM 2063 C "C3'" . G   B 2 14  ? 126.756 134.120 94.293  1.00 93.83  ? -12 G   B "C3'" 1 
ATOM 2064 O "O3'" . G   B 2 14  ? 126.416 134.864 93.138  1.00 93.83  ? -12 G   B "O3'" 1 
ATOM 2065 C "C2'" . G   B 2 14  ? 127.845 133.084 94.051  1.00 93.83  ? -12 G   B "C2'" 1 
ATOM 2066 O "O2'" . G   B 2 14  ? 128.872 133.618 93.227  1.00 93.83  ? -12 G   B "O2'" 1 
ATOM 2067 C "C1'" . G   B 2 14  ? 128.406 132.894 95.458  1.00 93.83  ? -12 G   B "C1'" 1 
ATOM 2068 N N9    . G   B 2 14  ? 127.809 131.747 96.168  1.00 93.83  ? -12 G   B N9    1 
ATOM 2069 C C8    . G   B 2 14  ? 126.895 131.832 97.190  1.00 93.83  ? -12 G   B C8    1 
ATOM 2070 N N7    . G   B 2 14  ? 126.541 130.672 97.666  1.00 93.83  ? -12 G   B N7    1 
ATOM 2071 C C5    . G   B 2 14  ? 127.273 129.766 96.918  1.00 93.83  ? -12 G   B C5    1 
ATOM 2072 C C6    . G   B 2 14  ? 127.310 128.358 96.993  1.00 93.83  ? -12 G   B C6    1 
ATOM 2073 O O6    . G   B 2 14  ? 126.672 127.603 97.724  1.00 93.83  ? -12 G   B O6    1 
ATOM 2074 N N1    . G   B 2 14  ? 128.171 127.806 96.051  1.00 93.83  ? -12 G   B N1    1 
ATOM 2075 C C2    . G   B 2 14  ? 128.934 128.525 95.167  1.00 93.83  ? -12 G   B C2    1 
ATOM 2076 N N2    . G   B 2 14  ? 129.698 127.775 94.352  1.00 93.83  ? -12 G   B N2    1 
ATOM 2077 N N3    . G   B 2 14  ? 128.916 129.850 95.086  1.00 93.83  ? -12 G   B N3    1 
ATOM 2078 C C4    . G   B 2 14  ? 128.069 130.404 95.988  1.00 93.83  ? -12 G   B C4    1 
ATOM 2079 P P     . G   B 2 15  ? 124.884 135.238 92.833  1.00 92.72  ? -11 G   B P     1 
ATOM 2080 O OP1   . G   B 2 15  ? 124.758 136.718 92.858  1.00 92.72  ? -11 G   B OP1   1 
ATOM 2081 O OP2   . G   B 2 15  ? 124.022 134.412 93.716  1.00 92.72  ? -11 G   B OP2   1 
ATOM 2082 O "O5'" . G   B 2 15  ? 124.668 134.751 91.333  1.00 92.72  ? -11 G   B "O5'" 1 
ATOM 2083 C "C5'" . G   B 2 15  ? 125.640 135.025 90.335  1.00 92.72  ? -11 G   B "C5'" 1 
ATOM 2084 C "C4'" . G   B 2 15  ? 126.252 133.755 89.802  1.00 92.72  ? -11 G   B "C4'" 1 
ATOM 2085 O "O4'" . G   B 2 15  ? 126.871 133.018 90.887  1.00 92.72  ? -11 G   B "O4'" 1 
ATOM 2086 C "C3'" . G   B 2 15  ? 125.283 132.760 89.186  1.00 92.72  ? -11 G   B "C3'" 1 
ATOM 2087 O "O3'" . G   B 2 15  ? 124.946 133.083 87.849  1.00 92.72  ? -11 G   B "O3'" 1 
ATOM 2088 C "C2'" . G   B 2 15  ? 126.025 131.436 89.328  1.00 92.72  ? -11 G   B "C2'" 1 
ATOM 2089 O "O2'" . G   B 2 15  ? 126.997 131.290 88.305  1.00 92.72  ? -11 G   B "O2'" 1 
ATOM 2090 C "C1'" . G   B 2 15  ? 126.750 131.631 90.659  1.00 92.72  ? -11 G   B "C1'" 1 
ATOM 2091 N N9    . G   B 2 15  ? 126.035 131.018 91.796  1.00 92.72  ? -11 G   B N9    1 
ATOM 2092 C C8    . G   B 2 15  ? 125.175 131.605 92.693  1.00 92.72  ? -11 G   B C8    1 
ATOM 2093 N N7    . G   B 2 15  ? 124.726 130.773 93.597  1.00 92.72  ? -11 G   B N7    1 
ATOM 2094 C C5    . G   B 2 15  ? 125.320 129.559 93.278  1.00 92.72  ? -11 G   B C5    1 
ATOM 2095 C C6    . G   B 2 15  ? 125.215 128.279 93.887  1.00 92.72  ? -11 G   B C6    1 
ATOM 2096 O O6    . G   B 2 15  ? 124.568 127.913 94.878  1.00 92.72  ? -11 G   B O6    1 
ATOM 2097 N N1    . G   B 2 15  ? 125.996 127.345 93.226  1.00 92.72  ? -11 G   B N1    1 
ATOM 2098 C C2    . G   B 2 15  ? 126.758 127.603 92.113  1.00 92.72  ? -11 G   B C2    1 
ATOM 2099 N N2    . G   B 2 15  ? 127.449 126.560 91.650  1.00 92.72  ? -11 G   B N2    1 
ATOM 2100 N N3    . G   B 2 15  ? 126.877 128.782 91.540  1.00 92.72  ? -11 G   B N3    1 
ATOM 2101 C C4    . G   B 2 15  ? 126.128 129.703 92.170  1.00 92.72  ? -11 G   B C4    1 
ATOM 2102 P P     . U   B 2 16  ? 123.501 132.698 87.262  1.00 93.31  ? -10 U   B P     1 
ATOM 2103 O OP1   . U   B 2 16  ? 123.387 133.279 85.901  1.00 93.31  ? -10 U   B OP1   1 
ATOM 2104 O OP2   . U   B 2 16  ? 122.480 133.025 88.290  1.00 93.31  ? -10 U   B OP2   1 
ATOM 2105 O "O5'" . U   B 2 16  ? 123.562 131.114 87.110  1.00 93.31  ? -10 U   B "O5'" 1 
ATOM 2106 C "C5'" . U   B 2 16  ? 124.498 130.504 86.236  1.00 93.31  ? -10 U   B "C5'" 1 
ATOM 2107 C "C4'" . U   B 2 16  ? 124.573 129.017 86.465  1.00 93.31  ? -10 U   B "C4'" 1 
ATOM 2108 O "O4'" . U   B 2 16  ? 125.115 128.748 87.783  1.00 93.31  ? -10 U   B "O4'" 1 
ATOM 2109 C "C3'" . U   B 2 16  ? 123.246 128.278 86.458  1.00 93.31  ? -10 U   B "C3'" 1 
ATOM 2110 O "O3'" . U   B 2 16  ? 122.769 128.011 85.152  1.00 93.31  ? -10 U   B "O3'" 1 
ATOM 2111 C "C2'" . U   B 2 16  ? 123.558 127.027 87.268  1.00 93.31  ? -10 U   B "C2'" 1 
ATOM 2112 O "O2'" . U   B 2 16  ? 124.251 126.075 86.474  1.00 93.31  ? -10 U   B "O2'" 1 
ATOM 2113 C "C1'" . U   B 2 16  ? 124.528 127.578 88.315  1.00 93.31  ? -10 U   B "C1'" 1 
ATOM 2114 N N1    . U   B 2 16  ? 123.844 127.917 89.583  1.00 93.31  ? -10 U   B N1    1 
ATOM 2115 C C2    . U   B 2 16  ? 123.675 126.896 90.496  1.00 93.31  ? -10 U   B C2    1 
ATOM 2116 O O2    . U   B 2 16  ? 124.064 125.759 90.296  1.00 93.31  ? -10 U   B O2    1 
ATOM 2117 N N3    . U   B 2 16  ? 123.037 127.255 91.654  1.00 93.31  ? -10 U   B N3    1 
ATOM 2118 C C4    . U   B 2 16  ? 122.556 128.503 91.984  1.00 93.31  ? -10 U   B C4    1 
ATOM 2119 O O4    . U   B 2 16  ? 122.001 128.668 93.071  1.00 93.31  ? -10 U   B O4    1 
ATOM 2120 C C5    . U   B 2 16  ? 122.768 129.506 90.989  1.00 93.31  ? -10 U   B C5    1 
ATOM 2121 C C6    . U   B 2 16  ? 123.391 129.187 89.851  1.00 93.31  ? -10 U   B C6    1 
ATOM 2122 P P     . U   B 2 17  ? 121.191 128.018 84.854  1.00 92.29  ? -9  U   B P     1 
ATOM 2123 O OP1   . U   B 2 17  ? 120.991 128.391 83.431  1.00 92.29  ? -9  U   B OP1   1 
ATOM 2124 O OP2   . U   B 2 17  ? 120.533 128.812 85.922  1.00 92.29  ? -9  U   B OP2   1 
ATOM 2125 O "O5'" . U   B 2 17  ? 120.755 126.497 85.034  1.00 92.29  ? -9  U   B "O5'" 1 
ATOM 2126 C "C5'" . U   B 2 17  ? 119.451 126.064 84.666  1.00 92.29  ? -9  U   B "C5'" 1 
ATOM 2127 C "C4'" . U   B 2 17  ? 119.429 124.608 84.270  1.00 92.29  ? -9  U   B "C4'" 1 
ATOM 2128 O "O4'" . U   B 2 17  ? 120.411 124.382 83.222  1.00 92.29  ? -9  U   B "O4'" 1 
ATOM 2129 C "C3'" . U   B 2 17  ? 119.751 123.613 85.388  1.00 92.29  ? -9  U   B "C3'" 1 
ATOM 2130 O "O3'" . U   B 2 17  ? 118.940 122.445 85.247  1.00 92.29  ? -9  U   B "O3'" 1 
ATOM 2131 C "C2'" . U   B 2 17  ? 121.216 123.263 85.126  1.00 92.29  ? -9  U   B "C2'" 1 
ATOM 2132 O "O2'" . U   B 2 17  ? 121.613 121.997 85.608  1.00 92.29  ? -9  U   B "O2'" 1 
ATOM 2133 C "C1'" . U   B 2 17  ? 121.284 123.337 83.601  1.00 92.29  ? -9  U   B "C1'" 1 
ATOM 2134 N N1    . U   B 2 17  ? 122.620 123.609 83.032  1.00 92.29  ? -9  U   B N1    1 
ATOM 2135 C C2    . U   B 2 17  ? 123.454 124.610 83.523  1.00 92.29  ? -9  U   B C2    1 
ATOM 2136 O O2    . U   B 2 17  ? 123.192 125.355 84.449  1.00 92.29  ? -9  U   B O2    1 
ATOM 2137 N N3    . U   B 2 17  ? 124.657 124.735 82.876  1.00 92.29  ? -9  U   B N3    1 
ATOM 2138 C C4    . U   B 2 17  ? 125.120 123.992 81.814  1.00 92.29  ? -9  U   B C4    1 
ATOM 2139 O O4    . U   B 2 17  ? 126.234 124.231 81.345  1.00 92.29  ? -9  U   B O4    1 
ATOM 2140 C C5    . U   B 2 17  ? 124.213 122.987 81.361  1.00 92.29  ? -9  U   B C5    1 
ATOM 2141 C C6    . U   B 2 17  ? 123.034 122.839 81.970  1.00 92.29  ? -9  U   B C6    1 
ATOM 2142 P P     . C   B 2 18  ? 117.365 122.506 85.578  1.00 92.24  ? -8  C   B P     1 
ATOM 2143 O OP1   . C   B 2 18  ? 116.644 121.986 84.390  1.00 92.24  ? -8  C   B OP1   1 
ATOM 2144 O OP2   . C   B 2 18  ? 117.040 123.860 86.090  1.00 92.24  ? -8  C   B OP2   1 
ATOM 2145 O "O5'" . C   B 2 18  ? 117.154 121.465 86.770  1.00 92.24  ? -8  C   B "O5'" 1 
ATOM 2146 C "C5'" . C   B 2 18  ? 118.128 121.300 87.798  1.00 92.24  ? -8  C   B "C5'" 1 
ATOM 2147 C "C4'" . C   B 2 18  ? 117.588 121.665 89.162  1.00 92.24  ? -8  C   B "C4'" 1 
ATOM 2148 O "O4'" . C   B 2 18  ? 118.425 122.717 89.714  1.00 92.24  ? -8  C   B "O4'" 1 
ATOM 2149 C "C3'" . C   B 2 18  ? 116.160 122.206 89.169  1.00 92.24  ? -8  C   B "C3'" 1 
ATOM 2150 O "O3'" . C   B 2 18  ? 115.406 121.804 90.329  1.00 92.24  ? -8  C   B "O3'" 1 
ATOM 2151 C "C2'" . C   B 2 18  ? 116.368 123.720 89.165  1.00 92.24  ? -8  C   B "C2'" 1 
ATOM 2152 O "O2'" . C   B 2 18  ? 115.302 124.461 89.721  1.00 92.24  ? -8  C   B "O2'" 1 
ATOM 2153 C "C1'" . C   B 2 18  ? 117.649 123.867 89.983  1.00 92.24  ? -8  C   B "C1'" 1 
ATOM 2154 N N1    . C   B 2 18  ? 118.449 125.048 89.635  1.00 92.24  ? -8  C   B N1    1 
ATOM 2155 C C2    . C   B 2 18  ? 118.565 126.073 90.569  1.00 92.24  ? -8  C   B C2    1 
ATOM 2156 O O2    . C   B 2 18  ? 117.990 125.945 91.656  1.00 92.24  ? -8  C   B O2    1 
ATOM 2157 N N3    . C   B 2 18  ? 119.294 127.168 90.266  1.00 92.24  ? -8  C   B N3    1 
ATOM 2158 C C4    . C   B 2 18  ? 119.893 127.253 89.081  1.00 92.24  ? -8  C   B C4    1 
ATOM 2159 N N4    . C   B 2 18  ? 120.600 128.349 88.815  1.00 92.24  ? -8  C   B N4    1 
ATOM 2160 C C5    . C   B 2 18  ? 119.791 126.221 88.109  1.00 92.24  ? -8  C   B C5    1 
ATOM 2161 C C6    . C   B 2 18  ? 119.064 125.145 88.424  1.00 92.24  ? -8  C   B C6    1 
ATOM 2162 P P     . G   B 2 19  ? 116.047 121.194 91.683  1.00 86.59  ? -7  G   B P     1 
ATOM 2163 O OP1   . G   B 2 19  ? 114.889 120.996 92.587  1.00 86.59  ? -7  G   B OP1   1 
ATOM 2164 O OP2   . G   B 2 19  ? 117.189 121.978 92.209  1.00 86.59  ? -7  G   B OP2   1 
ATOM 2165 O "O5'" . G   B 2 19  ? 116.553 119.736 91.295  1.00 86.59  ? -7  G   B "O5'" 1 
ATOM 2166 C "C5'" . G   B 2 19  ? 117.369 118.998 92.195  1.00 86.59  ? -7  G   B "C5'" 1 
ATOM 2167 C "C4'" . G   B 2 19  ? 118.245 118.014 91.466  1.00 86.59  ? -7  G   B "C4'" 1 
ATOM 2168 O "O4'" . G   B 2 19  ? 118.454 118.471 90.108  1.00 86.59  ? -7  G   B "O4'" 1 
ATOM 2169 C "C3'" . G   B 2 19  ? 119.652 117.834 92.018  1.00 86.59  ? -7  G   B "C3'" 1 
ATOM 2170 O "O3'" . G   B 2 19  ? 119.706 116.944 93.123  1.00 86.59  ? -7  G   B "O3'" 1 
ATOM 2171 C "C2'" . G   B 2 19  ? 120.431 117.340 90.803  1.00 86.59  ? -7  G   B "C2'" 1 
ATOM 2172 O "O2'" . G   B 2 19  ? 120.241 115.944 90.620  1.00 86.59  ? -7  G   B "O2'" 1 
ATOM 2173 C "C1'" . G   B 2 19  ? 119.729 118.077 89.658  1.00 86.59  ? -7  G   B "C1'" 1 
ATOM 2174 N N9    . G   B 2 19  ? 120.476 119.263 89.191  1.00 86.59  ? -7  G   B N9    1 
ATOM 2175 C C8    . G   B 2 19  ? 121.093 119.363 87.968  1.00 86.59  ? -7  G   B C8    1 
ATOM 2176 N N7    . G   B 2 19  ? 121.696 120.501 87.781  1.00 86.59  ? -7  G   B N7    1 
ATOM 2177 C C5    . G   B 2 19  ? 121.467 121.200 88.956  1.00 86.59  ? -7  G   B C5    1 
ATOM 2178 C C6    . G   B 2 19  ? 121.884 122.501 89.327  1.00 86.59  ? -7  G   B C6    1 
ATOM 2179 O O6    . G   B 2 19  ? 122.554 123.311 88.676  1.00 86.59  ? -7  G   B O6    1 
ATOM 2180 N N1    . G   B 2 19  ? 121.443 122.833 90.598  1.00 86.59  ? -7  G   B N1    1 
ATOM 2181 C C2    . G   B 2 19  ? 120.703 122.017 91.409  1.00 86.59  ? -7  G   B C2    1 
ATOM 2182 N N2    . G   B 2 19  ? 120.374 122.529 92.600  1.00 86.59  ? -7  G   B N2    1 
ATOM 2183 N N3    . G   B 2 19  ? 120.303 120.802 91.075  1.00 86.59  ? -7  G   B N3    1 
ATOM 2184 C C4    . G   B 2 19  ? 120.721 120.452 89.842  1.00 86.59  ? -7  G   B C4    1 
ATOM 2185 P P     . C   B 2 20  ? 120.487 117.350 94.470  1.00 78.02  ? -6  C   B P     1 
ATOM 2186 O OP1   . C   B 2 20  ? 121.036 116.121 95.086  1.00 78.02  ? -6  C   B OP1   1 
ATOM 2187 O OP2   . C   B 2 20  ? 119.634 118.270 95.257  1.00 78.02  ? -6  C   B OP2   1 
ATOM 2188 O "O5'" . C   B 2 20  ? 121.752 118.164 93.967  1.00 78.02  ? -6  C   B "O5'" 1 
ATOM 2189 C "C5'" . C   B 2 20  ? 122.978 117.505 93.696  1.00 78.02  ? -6  C   B "C5'" 1 
ATOM 2190 C "C4'" . C   B 2 20  ? 124.010 118.483 93.207  1.00 78.02  ? -6  C   B "C4'" 1 
ATOM 2191 O "O4'" . C   B 2 20  ? 123.331 119.663 92.701  1.00 78.02  ? -6  C   B "O4'" 1 
ATOM 2192 C "C3'" . C   B 2 20  ? 124.961 119.026 94.261  1.00 78.02  ? -6  C   B "C3'" 1 
ATOM 2193 O "O3'" . C   B 2 20  ? 126.053 118.165 94.527  1.00 78.02  ? -6  C   B "O3'" 1 
ATOM 2194 C "C2'" . C   B 2 20  ? 125.369 120.367 93.677  1.00 78.02  ? -6  C   B "C2'" 1 
ATOM 2195 O "O2'" . C   B 2 20  ? 126.336 120.194 92.652  1.00 78.02  ? -6  C   B "O2'" 1 
ATOM 2196 C "C1'" . C   B 2 20  ? 124.061 120.821 93.034  1.00 78.02  ? -6  C   B "C1'" 1 
ATOM 2197 N N1    . C   B 2 20  ? 123.241 121.638 93.958  1.00 78.02  ? -6  C   B N1    1 
ATOM 2198 C C2    . C   B 2 20  ? 123.560 122.986 94.132  1.00 78.02  ? -6  C   B C2    1 
ATOM 2199 O O2    . C   B 2 20  ? 124.519 123.464 93.508  1.00 78.02  ? -6  C   B O2    1 
ATOM 2200 N N3    . C   B 2 20  ? 122.817 123.736 94.976  1.00 78.02  ? -6  C   B N3    1 
ATOM 2201 C C4    . C   B 2 20  ? 121.793 123.191 95.629  1.00 78.02  ? -6  C   B C4    1 
ATOM 2202 N N4    . C   B 2 20  ? 121.088 123.973 96.450  1.00 78.02  ? -6  C   B N4    1 
ATOM 2203 C C5    . C   B 2 20  ? 121.445 121.821 95.472  1.00 78.02  ? -6  C   B C5    1 
ATOM 2204 C C6    . C   B 2 20  ? 122.188 121.093 94.634  1.00 78.02  ? -6  C   B C6    1 
ATOM 2205 P P     . C   B 2 21  ? 126.864 118.219 95.938  1.00 80.29  ? -5  C   B P     1 
ATOM 2206 O OP1   . C   B 2 21  ? 127.507 116.896 96.143  1.00 80.29  ? -5  C   B OP1   1 
ATOM 2207 O OP2   . C   B 2 21  ? 125.978 118.772 97.002  1.00 80.29  ? -5  C   B OP2   1 
ATOM 2208 O "O5'" . C   B 2 21  ? 128.033 119.260 95.644  1.00 80.29  ? -5  C   B "O5'" 1 
ATOM 2209 C "C5'" . C   B 2 21  ? 129.103 118.912 94.747  1.00 80.29  ? -5  C   B "C5'" 1 
ATOM 2210 C "C4'" . C   B 2 21  ? 129.712 120.149 94.132  1.00 80.29  ? -5  C   B "C4'" 1 
ATOM 2211 O "O4'" . C   B 2 21  ? 128.665 121.010 93.614  1.00 80.29  ? -5  C   B "O4'" 1 
ATOM 2212 C "C3'" . C   B 2 21  ? 130.458 121.073 95.077  1.00 80.29  ? -5  C   B "C3'" 1 
ATOM 2213 O "O3'" . C   B 2 21  ? 131.766 120.628 95.417  1.00 80.29  ? -5  C   B "O3'" 1 
ATOM 2214 C "C2'" . C   B 2 21  ? 130.497 122.365 94.274  1.00 80.29  ? -5  C   B "C2'" 1 
ATOM 2215 O "O2'" . C   B 2 21  ? 131.475 122.380 93.256  1.00 80.29  ? -5  C   B "O2'" 1 
ATOM 2216 C "C1'" . C   B 2 21  ? 129.116 122.355 93.622  1.00 80.29  ? -5  C   B "C1'" 1 
ATOM 2217 N N1    . C   B 2 21  ? 128.149 123.178 94.360  1.00 80.29  ? -5  C   B N1    1 
ATOM 2218 C C2    . C   B 2 21  ? 128.120 124.550 94.112  1.00 80.29  ? -5  C   B C2    1 
ATOM 2219 O O2    . C   B 2 21  ? 128.895 125.022 93.267  1.00 80.29  ? -5  C   B O2    1 
ATOM 2220 N N3    . C   B 2 21  ? 127.242 125.326 94.787  1.00 80.29  ? -5  C   B N3    1 
ATOM 2221 C C4    . C   B 2 21  ? 126.426 124.778 95.689  1.00 80.29  ? -5  C   B C4    1 
ATOM 2222 N N4    . C   B 2 21  ? 125.571 125.579 96.326  1.00 80.29  ? -5  C   B N4    1 
ATOM 2223 C C5    . C   B 2 21  ? 126.448 123.382 95.975  1.00 80.29  ? -5  C   B C5    1 
ATOM 2224 C C6    . C   B 2 21  ? 127.320 122.627 95.297  1.00 80.29  ? -5  C   B C6    1 
ATOM 2225 P P     . G   B 2 22  ? 132.494 121.151 96.767  1.00 86.23  ? -4  G   B P     1 
ATOM 2226 O OP1   . G   B 2 22  ? 133.638 120.241 97.025  1.00 86.23  ? -4  G   B OP1   1 
ATOM 2227 O OP2   . G   B 2 22  ? 131.465 121.355 97.818  1.00 86.23  ? -4  G   B OP2   1 
ATOM 2228 O "O5'" . G   B 2 22  ? 133.079 122.578 96.367  1.00 86.23  ? -4  G   B "O5'" 1 
ATOM 2229 C "C5'" . G   B 2 22  ? 133.956 122.724 95.260  1.00 86.23  ? -4  G   B "C5'" 1 
ATOM 2230 C "C4'" . G   B 2 22  ? 134.100 124.172 94.868  1.00 86.23  ? -4  G   B "C4'" 1 
ATOM 2231 O "O4'" . G   B 2 22  ? 132.784 124.749 94.657  1.00 86.23  ? -4  G   B "O4'" 1 
ATOM 2232 C "C3'" . G   B 2 22  ? 134.739 125.071 95.914  1.00 86.23  ? -4  G   B "C3'" 1 
ATOM 2233 O "O3'" . G   B 2 22  ? 136.153 125.019 95.886  1.00 86.23  ? -4  G   B "O3'" 1 
ATOM 2234 C "C2'" . G   B 2 22  ? 134.168 126.439 95.574  1.00 86.23  ? -4  G   B "C2'" 1 
ATOM 2235 O "O2'" . G   B 2 22  ? 134.840 127.000 94.456  1.00 86.23  ? -4  G   B "O2'" 1 
ATOM 2236 C "C1'" . G   B 2 22  ? 132.749 126.071 95.149  1.00 86.23  ? -4  G   B "C1'" 1 
ATOM 2237 N N9    . G   B 2 22  ? 131.812 126.105 96.285  1.00 86.23  ? -4  G   B N9    1 
ATOM 2238 C C8    . G   B 2 22  ? 131.219 125.019 96.879  1.00 86.23  ? -4  G   B C8    1 
ATOM 2239 N N7    . G   B 2 22  ? 130.434 125.339 97.868  1.00 86.23  ? -4  G   B N7    1 
ATOM 2240 C C5    . G   B 2 22  ? 130.515 126.720 97.931  1.00 86.23  ? -4  G   B C5    1 
ATOM 2241 C C6    . G   B 2 22  ? 129.880 127.628 98.809  1.00 86.23  ? -4  G   B C6    1 
ATOM 2242 O O6    . G   B 2 22  ? 129.095 127.383 99.731  1.00 86.23  ? -4  G   B O6    1 
ATOM 2243 N N1    . G   B 2 22  ? 130.235 128.942 98.529  1.00 86.23  ? -4  G   B N1    1 
ATOM 2244 C C2    . G   B 2 22  ? 131.094 129.331 97.533  1.00 86.23  ? -4  G   B C2    1 
ATOM 2245 N N2    . G   B 2 22  ? 131.312 130.649 97.422  1.00 86.23  ? -4  G   B N2    1 
ATOM 2246 N N3    . G   B 2 22  ? 131.695 128.491 96.706  1.00 86.23  ? -4  G   B N3    1 
ATOM 2247 C C4    . G   B 2 22  ? 131.360 127.210 96.962  1.00 86.23  ? -4  G   B C4    1 
ATOM 2248 P P     . A   B 2 23  ? 136.978 124.800 97.246  1.00 86.79  ? -3  A   B P     1 
ATOM 2249 O OP1   . A   B 2 23  ? 138.350 124.355 96.892  1.00 86.79  ? -3  A   B OP1   1 
ATOM 2250 O OP2   . A   B 2 23  ? 136.144 123.966 98.148  1.00 86.79  ? -3  A   B OP2   1 
ATOM 2251 O "O5'" . A   B 2 23  ? 137.079 126.261 97.873  1.00 86.79  ? -3  A   B "O5'" 1 
ATOM 2252 C "C5'" . A   B 2 23  ? 137.557 126.457 99.196  1.00 86.79  ? -3  A   B "C5'" 1 
ATOM 2253 C "C4'" . A   B 2 23  ? 137.266 127.853 99.680  1.00 86.79  ? -3  A   B "C4'" 1 
ATOM 2254 O "O4'" . A   B 2 23  ? 135.932 128.244 99.263  1.00 86.79  ? -3  A   B "O4'" 1 
ATOM 2255 C "C3'" . A   B 2 23  ? 137.251 128.044 101.187 1.00 86.79  ? -3  A   B "C3'" 1 
ATOM 2256 O "O3'" . A   B 2 23  ? 138.545 128.188 101.745 1.00 86.79  ? -3  A   B "O3'" 1 
ATOM 2257 C "C2'" . A   B 2 23  ? 136.369 129.272 101.356 1.00 86.79  ? -3  A   B "C2'" 1 
ATOM 2258 O "O2'" . A   B 2 23  ? 137.093 130.455 101.048 1.00 86.79  ? -3  A   B "O2'" 1 
ATOM 2259 C "C1'" . A   B 2 23  ? 135.331 129.044 100.259 1.00 86.79  ? -3  A   B "C1'" 1 
ATOM 2260 N N9    . A   B 2 23  ? 134.145 128.333 100.768 1.00 86.79  ? -3  A   B N9    1 
ATOM 2261 C C8    . A   B 2 23  ? 133.792 127.029 100.532 1.00 86.79  ? -3  A   B C8    1 
ATOM 2262 N N7    . A   B 2 23  ? 132.680 126.669 101.121 1.00 86.79  ? -3  A   B N7    1 
ATOM 2263 C C5    . A   B 2 23  ? 132.276 127.811 101.791 1.00 86.79  ? -3  A   B C5    1 
ATOM 2264 C C6    . A   B 2 23  ? 131.167 128.080 102.606 1.00 86.79  ? -3  A   B C6    1 
ATOM 2265 N N6    . A   B 2 23  ? 130.227 127.177 102.888 1.00 86.79  ? -3  A   B N6    1 
ATOM 2266 N N1    . A   B 2 23  ? 131.049 129.320 103.125 1.00 86.79  ? -3  A   B N1    1 
ATOM 2267 C C2    . A   B 2 23  ? 131.994 130.223 102.837 1.00 86.79  ? -3  A   B C2    1 
ATOM 2268 N N3    . A   B 2 23  ? 133.084 130.088 102.083 1.00 86.79  ? -3  A   B N3    1 
ATOM 2269 C C4    . A   B 2 23  ? 133.167 128.844 101.584 1.00 86.79  ? -3  A   B C4    1 
ATOM 2270 P P     . G   B 2 24  ? 138.910 127.457 103.129 1.00 87.01  ? -2  G   B P     1 
ATOM 2271 O OP1   . G   B 2 24  ? 140.334 127.743 103.439 1.00 87.01  ? -2  G   B OP1   1 
ATOM 2272 O OP2   . G   B 2 24  ? 138.447 126.048 103.038 1.00 87.01  ? -2  G   B OP2   1 
ATOM 2273 O "O5'" . G   B 2 24  ? 138.010 128.203 104.211 1.00 87.01  ? -2  G   B "O5'" 1 
ATOM 2274 C "C5'" . G   B 2 24  ? 138.285 129.545 104.587 1.00 87.01  ? -2  G   B "C5'" 1 
ATOM 2275 C "C4'" . G   B 2 24  ? 137.438 129.981 105.756 1.00 87.01  ? -2  G   B "C4'" 1 
ATOM 2276 O "O4'" . G   B 2 24  ? 136.061 130.128 105.342 1.00 87.01  ? -2  G   B "O4'" 1 
ATOM 2277 C "C3'" . G   B 2 24  ? 137.377 129.021 106.933 1.00 87.01  ? -2  G   B "C3'" 1 
ATOM 2278 O "O3'" . G   B 2 24  ? 138.499 129.165 107.789 1.00 87.01  ? -2  G   B "O3'" 1 
ATOM 2279 C "C2'" . G   B 2 24  ? 136.051 129.375 107.605 1.00 87.01  ? -2  G   B "C2'" 1 
ATOM 2280 O "O2'" . G   B 2 24  ? 136.218 130.465 108.499 1.00 87.01  ? -2  G   B "O2'" 1 
ATOM 2281 C "C1'" . G   B 2 24  ? 135.200 129.847 106.422 1.00 87.01  ? -2  G   B "C1'" 1 
ATOM 2282 N N9    . G   B 2 24  ? 134.180 128.876 105.984 1.00 87.01  ? -2  G   B N9    1 
ATOM 2283 C C8    . G   B 2 24  ? 134.328 127.806 105.137 1.00 87.01  ? -2  G   B C8    1 
ATOM 2284 N N7    . G   B 2 24  ? 133.210 127.164 104.926 1.00 87.01  ? -2  G   B N7    1 
ATOM 2285 C C5    . G   B 2 24  ? 132.268 127.858 105.668 1.00 87.01  ? -2  G   B C5    1 
ATOM 2286 C C6    . G   B 2 24  ? 130.878 127.641 105.834 1.00 87.01  ? -2  G   B C6    1 
ATOM 2287 O O6    . G   B 2 24  ? 130.161 126.758 105.359 1.00 87.01  ? -2  G   B O6    1 
ATOM 2288 N N1    . G   B 2 24  ? 130.304 128.580 106.679 1.00 87.01  ? -2  G   B N1    1 
ATOM 2289 C C2    . G   B 2 24  ? 130.976 129.612 107.275 1.00 87.01  ? -2  G   B C2    1 
ATOM 2290 N N2    . G   B 2 24  ? 130.230 130.409 108.051 1.00 87.01  ? -2  G   B N2    1 
ATOM 2291 N N3    . G   B 2 24  ? 132.273 129.829 107.136 1.00 87.01  ? -2  G   B N3    1 
ATOM 2292 C C4    . G   B 2 24  ? 132.851 128.919 106.323 1.00 87.01  ? -2  G   B C4    1 
ATOM 2293 P P     . A   B 2 25  ? 138.660 128.259 109.106 1.00 89.54  ? -1  A   B P     1 
ATOM 2294 O OP1   . A   B 2 25  ? 140.085 128.303 109.522 1.00 89.54  ? -1  A   B OP1   1 
ATOM 2295 O OP2   . A   B 2 25  ? 138.014 126.948 108.843 1.00 89.54  ? -1  A   B OP2   1 
ATOM 2296 O "O5'" . A   B 2 25  ? 137.799 129.017 110.213 1.00 89.54  ? -1  A   B "O5'" 1 
ATOM 2297 C "C5'" . A   B 2 25  ? 138.315 130.129 110.935 1.00 89.54  ? -1  A   B "C5'" 1 
ATOM 2298 C "C4'" . A   B 2 25  ? 137.443 130.431 112.127 1.00 89.54  ? -1  A   B "C4'" 1 
ATOM 2299 O "O4'" . A   B 2 25  ? 136.116 130.785 111.658 1.00 89.54  ? -1  A   B "O4'" 1 
ATOM 2300 C "C3'" . A   B 2 25  ? 137.232 129.254 113.072 1.00 89.54  ? -1  A   B "C3'" 1 
ATOM 2301 O "O3'" . A   B 2 25  ? 138.215 129.218 114.097 1.00 89.54  ? -1  A   B "O3'" 1 
ATOM 2302 C "C2'" . A   B 2 25  ? 135.819 129.460 113.603 1.00 89.54  ? -1  A   B "C2'" 1 
ATOM 2303 O "O2'" . A   B 2 25  ? 135.824 130.361 114.700 1.00 89.54  ? -1  A   B "O2'" 1 
ATOM 2304 C "C1'" . A   B 2 25  ? 135.129 130.145 112.431 1.00 89.54  ? -1  A   B "C1'" 1 
ATOM 2305 N N9    . A   B 2 25  ? 134.393 129.233 111.535 1.00 89.54  ? -1  A   B N9    1 
ATOM 2306 C C8    . A   B 2 25  ? 134.914 128.299 110.678 1.00 89.54  ? -1  A   B C8    1 
ATOM 2307 N N7    . A   B 2 25  ? 134.015 127.680 109.955 1.00 89.54  ? -1  A   B N7    1 
ATOM 2308 C C5    . A   B 2 25  ? 132.822 128.262 110.345 1.00 89.54  ? -1  A   B C5    1 
ATOM 2309 C C6    . A   B 2 25  ? 131.496 128.040 109.949 1.00 89.54  ? -1  A   B C6    1 
ATOM 2310 N N6    . A   B 2 25  ? 131.151 127.134 109.033 1.00 89.54  ? -1  A   B N6    1 
ATOM 2311 N N1    . A   B 2 25  ? 130.527 128.779 110.528 1.00 89.54  ? -1  A   B N1    1 
ATOM 2312 C C2    . A   B 2 25  ? 130.889 129.688 111.442 1.00 89.54  ? -1  A   B C2    1 
ATOM 2313 N N3    . A   B 2 25  ? 132.103 129.989 111.901 1.00 89.54  ? -1  A   B N3    1 
ATOM 2314 C C4    . A   B 2 25  ? 133.039 129.232 111.303 1.00 89.54  ? -1  A   B C4    1 
ATOM 2315 P P     . C   B 2 26  ? 138.612 127.839 114.823 1.00 89.30  ? 0   C   B P     1 
ATOM 2316 O OP1   . C   B 2 26  ? 139.872 128.067 115.575 1.00 89.30  ? 0   C   B OP1   1 
ATOM 2317 O OP2   . C   B 2 26  ? 138.550 126.755 113.810 1.00 89.30  ? 0   C   B OP2   1 
ATOM 2318 O "O5'" . C   B 2 26  ? 137.446 127.594 115.881 1.00 89.30  ? 0   C   B "O5'" 1 
ATOM 2319 C "C5'" . C   B 2 26  ? 137.148 128.537 116.904 1.00 89.30  ? 0   C   B "C5'" 1 
ATOM 2320 C "C4'" . C   B 2 26  ? 135.726 128.371 117.376 1.00 89.30  ? 0   C   B "C4'" 1 
ATOM 2321 O "O4'" . C   B 2 26  ? 134.843 128.622 116.257 1.00 89.30  ? 0   C   B "O4'" 1 
ATOM 2322 C "C3'" . C   B 2 26  ? 135.356 126.975 117.863 1.00 89.30  ? 0   C   B "C3'" 1 
ATOM 2323 O "O3'" . C   B 2 26  ? 135.594 126.803 119.250 1.00 89.30  ? 0   C   B "O3'" 1 
ATOM 2324 C "C2'" . C   B 2 26  ? 133.876 126.853 117.508 1.00 89.30  ? 0   C   B "C2'" 1 
ATOM 2325 O "O2'" . C   B 2 26  ? 133.068 127.443 118.516 1.00 89.30  ? 0   C   B "O2'" 1 
ATOM 2326 C "C1'" . C   B 2 26  ? 133.774 127.711 116.248 1.00 89.30  ? 0   C   B "C1'" 1 
ATOM 2327 N N1    . C   B 2 26  ? 133.836 126.922 114.993 1.00 89.30  ? 0   C   B N1    1 
ATOM 2328 C C2    . C   B 2 26  ? 132.712 126.925 114.165 1.00 89.30  ? 0   C   B C2    1 
ATOM 2329 O O2    . C   B 2 26  ? 131.722 127.583 114.513 1.00 89.30  ? 0   C   B O2    1 
ATOM 2330 N N3    . C   B 2 26  ? 132.729 126.225 113.007 1.00 89.30  ? 0   C   B N3    1 
ATOM 2331 C C4    . C   B 2 26  ? 133.813 125.531 112.665 1.00 89.30  ? 0   C   B C4    1 
ATOM 2332 N N4    . C   B 2 26  ? 133.793 124.848 111.520 1.00 89.30  ? 0   C   B N4    1 
ATOM 2333 C C5    . C   B 2 26  ? 134.972 125.505 113.487 1.00 89.30  ? 0   C   B C5    1 
ATOM 2334 C C6    . C   B 2 26  ? 134.940 126.206 114.626 1.00 89.30  ? 0   C   B C6    1 
ATOM 2335 P P     . U   B 2 27  ? 137.032 126.361 119.818 1.00 101.65 ? 1   U   B P     1 
ATOM 2336 O OP1   . U   B 2 27  ? 138.050 126.359 118.741 1.00 101.65 ? 1   U   B OP1   1 
ATOM 2337 O OP2   . U   B 2 27  ? 136.814 125.112 120.585 1.00 101.65 ? 1   U   B OP2   1 
ATOM 2338 O "O5'" . U   B 2 27  ? 137.386 127.509 120.867 1.00 101.65 ? 1   U   B "O5'" 1 
ATOM 2339 C "C5'" . U   B 2 27  ? 136.948 128.850 120.659 1.00 101.65 ? 1   U   B "C5'" 1 
ATOM 2340 C "C4'" . U   B 2 27  ? 135.666 129.144 121.401 1.00 101.65 ? 1   U   B "C4'" 1 
ATOM 2341 O "O4'" . U   B 2 27  ? 135.953 129.236 122.823 1.00 101.65 ? 1   U   B "O4'" 1 
ATOM 2342 C "C3'" . U   B 2 27  ? 134.975 130.452 121.019 1.00 101.65 ? 1   U   B "C3'" 1 
ATOM 2343 O "O3'" . U   B 2 27  ? 133.558 130.295 121.112 1.00 101.65 ? 1   U   B "O3'" 1 
ATOM 2344 C "C2'" . U   B 2 27  ? 135.455 131.413 122.100 1.00 101.65 ? 1   U   B "C2'" 1 
ATOM 2345 O "O2'" . U   B 2 27  ? 134.601 132.513 122.329 1.00 101.65 ? 1   U   B "O2'" 1 
ATOM 2346 C "C1'" . U   B 2 27  ? 135.538 130.496 123.316 1.00 101.65 ? 1   U   B "C1'" 1 
ATOM 2347 N N1    . U   B 2 27  ? 136.517 130.934 124.321 1.00 101.65 ? 1   U   B N1    1 
ATOM 2348 C C2    . U   B 2 27  ? 136.186 130.799 125.655 1.00 101.65 ? 1   U   B C2    1 
ATOM 2349 O O2    . U   B 2 27  ? 135.128 130.325 126.029 1.00 101.65 ? 1   U   B O2    1 
ATOM 2350 N N3    . U   B 2 27  ? 137.144 131.230 126.538 1.00 101.65 ? 1   U   B N3    1 
ATOM 2351 C C4    . U   B 2 27  ? 138.373 131.777 126.228 1.00 101.65 ? 1   U   B C4    1 
ATOM 2352 O O4    . U   B 2 27  ? 139.130 132.121 127.138 1.00 101.65 ? 1   U   B O4    1 
ATOM 2353 C C5    . U   B 2 27  ? 138.639 131.889 124.827 1.00 101.65 ? 1   U   B C5    1 
ATOM 2354 C C6    . U   B 2 27  ? 137.724 131.475 123.944 1.00 101.65 ? 1   U   B C6    1 
ATOM 2355 P P     . C   B 2 28  ? 132.590 131.053 120.075 1.00 103.46 ? 2   C   B P     1 
ATOM 2356 O OP1   . C   B 2 28  ? 133.189 130.927 118.722 1.00 103.46 ? 2   C   B OP1   1 
ATOM 2357 O OP2   . C   B 2 28  ? 132.290 132.399 120.625 1.00 103.46 ? 2   C   B OP2   1 
ATOM 2358 O "O5'" . C   B 2 28  ? 131.242 130.201 120.100 1.00 103.46 ? 2   C   B "O5'" 1 
ATOM 2359 C "C5'" . C   B 2 28  ? 129.971 130.836 120.039 1.00 103.46 ? 2   C   B "C5'" 1 
ATOM 2360 C "C4'" . C   B 2 28  ? 129.062 130.332 121.131 1.00 103.46 ? 2   C   B "C4'" 1 
ATOM 2361 O "O4'" . C   B 2 28  ? 129.856 129.618 122.110 1.00 103.46 ? 2   C   B "O4'" 1 
ATOM 2362 C "C3'" . C   B 2 28  ? 128.332 131.401 121.935 1.00 103.46 ? 2   C   B "C3'" 1 
ATOM 2363 O "O3'" . C   B 2 28  ? 127.125 131.819 121.315 1.00 103.46 ? 2   C   B "O3'" 1 
ATOM 2364 C "C2'" . C   B 2 28  ? 128.126 130.736 123.291 1.00 103.46 ? 2   C   B "C2'" 1 
ATOM 2365 O "O2'" . C   B 2 28  ? 126.990 129.883 123.268 1.00 103.46 ? 2   C   B "O2'" 1 
ATOM 2366 C "C1'" . C   B 2 28  ? 129.376 129.867 123.410 1.00 103.46 ? 2   C   B "C1'" 1 
ATOM 2367 N N1    . C   B 2 28  ? 130.463 130.509 124.187 1.00 103.46 ? 2   C   B N1    1 
ATOM 2368 C C2    . C   B 2 28  ? 130.688 130.076 125.493 1.00 103.46 ? 2   C   B C2    1 
ATOM 2369 O O2    . C   B 2 28  ? 129.963 129.186 125.959 1.00 103.46 ? 2   C   B O2    1 
ATOM 2370 N N3    . C   B 2 28  ? 131.685 130.634 126.211 1.00 103.46 ? 2   C   B N3    1 
ATOM 2371 C C4    . C   B 2 28  ? 132.443 131.587 125.671 1.00 103.46 ? 2   C   B C4    1 
ATOM 2372 N N4    . C   B 2 28  ? 133.417 132.111 126.416 1.00 103.46 ? 2   C   B N4    1 
ATOM 2373 C C5    . C   B 2 28  ? 132.244 132.045 124.340 1.00 103.46 ? 2   C   B C5    1 
ATOM 2374 C C6    . C   B 2 28  ? 131.256 131.480 123.642 1.00 103.46 ? 2   C   B C6    1 
ATOM 2375 P P     . C   B 2 29  ? 126.139 132.856 122.049 1.00 101.72 ? 3   C   B P     1 
ATOM 2376 O OP1   . C   B 2 29  ? 125.176 133.375 121.046 1.00 101.72 ? 3   C   B OP1   1 
ATOM 2377 O OP2   . C   B 2 29  ? 126.966 133.809 122.829 1.00 101.72 ? 3   C   B OP2   1 
ATOM 2378 O "O5'" . C   B 2 29  ? 125.314 131.957 123.073 1.00 101.72 ? 3   C   B "O5'" 1 
ATOM 2379 C "C5'" . C   B 2 29  ? 124.485 132.555 124.056 1.00 101.72 ? 3   C   B "C5'" 1 
ATOM 2380 C "C4'" . C   B 2 29  ? 124.704 131.946 125.419 1.00 101.72 ? 3   C   B "C4'" 1 
ATOM 2381 O "O4'" . C   B 2 29  ? 126.086 131.530 125.551 1.00 101.72 ? 3   C   B "O4'" 1 
ATOM 2382 C "C3'" . C   B 2 29  ? 124.477 132.881 126.597 1.00 101.72 ? 3   C   B "C3'" 1 
ATOM 2383 O "O3'" . C   B 2 29  ? 123.112 132.974 126.965 1.00 101.72 ? 3   C   B "O3'" 1 
ATOM 2384 C "C2'" . C   B 2 29  ? 125.358 132.282 127.686 1.00 101.72 ? 3   C   B "C2'" 1 
ATOM 2385 O "O2'" . C   B 2 29  ? 124.707 131.188 128.314 1.00 101.72 ? 3   C   B "O2'" 1 
ATOM 2386 C "C1'" . C   B 2 29  ? 126.533 131.739 126.871 1.00 101.72 ? 3   C   B "C1'" 1 
ATOM 2387 N N1    . C   B 2 29  ? 127.689 132.664 126.833 1.00 101.72 ? 3   C   B N1    1 
ATOM 2388 C C2    . C   B 2 29  ? 128.563 132.710 127.918 1.00 101.72 ? 3   C   B C2    1 
ATOM 2389 O O2    . C   B 2 29  ? 128.337 131.986 128.897 1.00 101.72 ? 3   C   B O2    1 
ATOM 2390 N N3    . C   B 2 29  ? 129.626 133.543 127.878 1.00 101.72 ? 3   C   B N3    1 
ATOM 2391 C C4    . C   B 2 29  ? 129.837 134.306 126.806 1.00 101.72 ? 3   C   B C4    1 
ATOM 2392 N N4    . C   B 2 29  ? 130.899 135.115 126.810 1.00 101.72 ? 3   C   B N4    1 
ATOM 2393 C C5    . C   B 2 29  ? 128.967 134.277 125.680 1.00 101.72 ? 3   C   B C5    1 
ATOM 2394 C C6    . C   B 2 29  ? 127.920 133.445 125.736 1.00 101.72 ? 3   C   B C6    1 
ATOM 2395 P P     . C   B 2 30  ? 122.151 134.054 126.265 1.00 103.76 ? 4   C   B P     1 
ATOM 2396 O OP1   . C   B 2 30  ? 121.488 133.394 125.112 1.00 103.76 ? 4   C   B OP1   1 
ATOM 2397 O OP2   . C   B 2 30  ? 122.936 135.295 126.042 1.00 103.76 ? 4   C   B OP2   1 
ATOM 2398 O "O5'" . C   B 2 30  ? 121.050 134.362 127.374 1.00 103.76 ? 4   C   B "O5'" 1 
ATOM 2399 C "C5'" . C   B 2 30  ? 121.161 135.500 128.217 1.00 103.76 ? 4   C   B "C5'" 1 
ATOM 2400 C "C4'" . C   B 2 30  ? 121.927 135.187 129.478 1.00 103.76 ? 4   C   B "C4'" 1 
ATOM 2401 O "O4'" . C   B 2 30  ? 123.300 134.855 129.148 1.00 103.76 ? 4   C   B "O4'" 1 
ATOM 2402 C "C3'" . C   B 2 30  ? 122.052 136.327 130.477 1.00 103.76 ? 4   C   B "C3'" 1 
ATOM 2403 O "O3'" . C   B 2 30  ? 120.906 136.476 131.297 1.00 103.76 ? 4   C   B "O3'" 1 
ATOM 2404 C "C2'" . C   B 2 30  ? 123.311 135.957 131.250 1.00 103.76 ? 4   C   B "C2'" 1 
ATOM 2405 O "O2'" . C   B 2 30  ? 123.035 134.952 132.213 1.00 103.76 ? 4   C   B "O2'" 1 
ATOM 2406 C "C1'" . C   B 2 30  ? 124.170 135.341 130.148 1.00 103.76 ? 4   C   B "C1'" 1 
ATOM 2407 N N1    . C   B 2 30  ? 125.083 136.332 129.536 1.00 103.76 ? 4   C   B N1    1 
ATOM 2408 C C2    . C   B 2 30  ? 126.215 136.744 130.245 1.00 103.76 ? 4   C   B C2    1 
ATOM 2409 O O2    . C   B 2 30  ? 126.429 136.277 131.374 1.00 103.76 ? 4   C   B O2    1 
ATOM 2410 N N3    . C   B 2 30  ? 127.052 137.645 129.687 1.00 103.76 ? 4   C   B N3    1 
ATOM 2411 C C4    . C   B 2 30  ? 126.795 138.130 128.473 1.00 103.76 ? 4   C   B C4    1 
ATOM 2412 N N4    . C   B 2 30  ? 127.651 139.017 127.963 1.00 103.76 ? 4   C   B N4    1 
ATOM 2413 C C5    . C   B 2 30  ? 125.652 137.729 127.725 1.00 103.76 ? 4   C   B C5    1 
ATOM 2414 C C6    . C   B 2 30  ? 124.832 136.836 128.291 1.00 103.76 ? 4   C   B C6    1 
ATOM 2415 P P     . DG  C 3 29  ? 132.700 143.584 131.324 1.00 112.14 ? -4  DG  C P     1 
ATOM 2416 O OP1   . DG  C 3 29  ? 131.513 144.333 130.855 1.00 112.14 ? -4  DG  C OP1   1 
ATOM 2417 O OP2   . DG  C 3 29  ? 133.727 144.265 132.144 1.00 112.14 ? -4  DG  C OP2   1 
ATOM 2418 O "O5'" . DG  C 3 29  ? 132.221 142.278 132.116 1.00 112.14 ? -4  DG  C "O5'" 1 
ATOM 2419 C "C5'" . DG  C 3 29  ? 132.559 142.112 133.490 1.00 112.14 ? -4  DG  C "C5'" 1 
ATOM 2420 C "C4'" . DG  C 3 29  ? 131.630 141.115 134.163 1.00 112.14 ? -4  DG  C "C4'" 1 
ATOM 2421 O "O4'" . DG  C 3 29  ? 130.269 141.345 133.717 1.00 112.14 ? -4  DG  C "O4'" 1 
ATOM 2422 C "C3'" . DG  C 3 29  ? 131.920 139.651 133.860 1.00 112.14 ? -4  DG  C "C3'" 1 
ATOM 2423 O "O3'" . DG  C 3 29  ? 131.550 138.842 134.973 1.00 112.14 ? -4  DG  C "O3'" 1 
ATOM 2424 C "C2'" . DG  C 3 29  ? 131.028 139.382 132.654 1.00 112.14 ? -4  DG  C "C2'" 1 
ATOM 2425 C "C1'" . DG  C 3 29  ? 129.803 140.231 132.979 1.00 112.14 ? -4  DG  C "C1'" 1 
ATOM 2426 N N9    . DG  C 3 29  ? 129.106 140.725 131.794 1.00 112.14 ? -4  DG  C N9    1 
ATOM 2427 C C8    . DG  C 3 29  ? 129.664 141.378 130.722 1.00 112.14 ? -4  DG  C C8    1 
ATOM 2428 N N7    . DG  C 3 29  ? 128.798 141.710 129.807 1.00 112.14 ? -4  DG  C N7    1 
ATOM 2429 C C5    . DG  C 3 29  ? 127.586 141.251 130.302 1.00 112.14 ? -4  DG  C C5    1 
ATOM 2430 C C6    . DG  C 3 29  ? 126.290 141.327 129.744 1.00 112.14 ? -4  DG  C C6    1 
ATOM 2431 O O6    . DG  C 3 29  ? 125.950 141.830 128.665 1.00 112.14 ? -4  DG  C O6    1 
ATOM 2432 N N1    . DG  C 3 29  ? 125.336 140.741 130.570 1.00 112.14 ? -4  DG  C N1    1 
ATOM 2433 C C2    . DG  C 3 29  ? 125.601 140.155 131.783 1.00 112.14 ? -4  DG  C C2    1 
ATOM 2434 N N2    . DG  C 3 29  ? 124.546 139.642 132.433 1.00 112.14 ? -4  DG  C N2    1 
ATOM 2435 N N3    . DG  C 3 29  ? 126.813 140.076 132.321 1.00 112.14 ? -4  DG  C N3    1 
ATOM 2436 C C4    . DG  C 3 29  ? 127.755 140.644 131.526 1.00 112.14 ? -4  DG  C C4    1 
ATOM 2437 P P     . DG  C 3 30  ? 132.676 138.129 135.873 1.00 113.22 ? -3  DG  C P     1 
ATOM 2438 O OP1   . DG  C 3 30  ? 133.428 139.195 136.571 1.00 113.22 ? -3  DG  C OP1   1 
ATOM 2439 O OP2   . DG  C 3 30  ? 133.402 137.163 135.019 1.00 113.22 ? -3  DG  C OP2   1 
ATOM 2440 O "O5'" . DG  C 3 30  ? 131.832 137.301 136.953 1.00 113.22 ? -3  DG  C "O5'" 1 
ATOM 2441 C "C5'" . DG  C 3 30  ? 132.278 136.017 137.380 1.00 113.22 ? -3  DG  C "C5'" 1 
ATOM 2442 C "C4'" . DG  C 3 30  ? 131.103 135.073 137.560 1.00 113.22 ? -3  DG  C "C4'" 1 
ATOM 2443 O "O4'" . DG  C 3 30  ? 130.139 135.306 136.501 1.00 113.22 ? -3  DG  C "O4'" 1 
ATOM 2444 C "C3'" . DG  C 3 30  ? 131.442 133.598 137.443 1.00 113.22 ? -3  DG  C "C3'" 1 
ATOM 2445 O "O3'" . DG  C 3 30  ? 130.411 132.825 138.052 1.00 113.22 ? -3  DG  C "O3'" 1 
ATOM 2446 C "C2'" . DG  C 3 30  ? 131.432 133.424 135.933 1.00 113.22 ? -3  DG  C "C2'" 1 
ATOM 2447 C "C1'" . DG  C 3 30  ? 130.196 134.238 135.569 1.00 113.22 ? -3  DG  C "C1'" 1 
ATOM 2448 N N9    . DG  C 3 30  ? 130.226 134.804 134.223 1.00 113.22 ? -3  DG  C N9    1 
ATOM 2449 C C8    . DG  C 3 30  ? 131.054 135.796 133.761 1.00 113.22 ? -3  DG  C C8    1 
ATOM 2450 N N7    . DG  C 3 30  ? 130.842 136.111 132.513 1.00 113.22 ? -3  DG  C N7    1 
ATOM 2451 C C5    . DG  C 3 30  ? 129.802 135.279 132.125 1.00 113.22 ? -3  DG  C C5    1 
ATOM 2452 C C6    . DG  C 3 30  ? 129.142 135.165 130.878 1.00 113.22 ? -3  DG  C C6    1 
ATOM 2453 O O6    . DG  C 3 30  ? 129.353 135.801 129.836 1.00 113.22 ? -3  DG  C O6    1 
ATOM 2454 N N1    . DG  C 3 30  ? 128.142 134.197 130.912 1.00 113.22 ? -3  DG  C N1    1 
ATOM 2455 C C2    . DG  C 3 30  ? 127.822 133.434 132.010 1.00 113.22 ? -3  DG  C C2    1 
ATOM 2456 N N2    . DG  C 3 30  ? 126.827 132.550 131.850 1.00 113.22 ? -3  DG  C N2    1 
ATOM 2457 N N3    . DG  C 3 30  ? 128.433 133.530 133.183 1.00 113.22 ? -3  DG  C N3    1 
ATOM 2458 C C4    . DG  C 3 30  ? 129.409 134.470 133.167 1.00 113.22 ? -3  DG  C C4    1 
ATOM 2459 P P     . DG  C 3 31  ? 130.727 131.379 138.681 1.00 105.29 ? -2  DG  C P     1 
ATOM 2460 O OP1   . DG  C 3 31  ? 129.446 130.644 138.747 1.00 105.29 ? -2  DG  C OP1   1 
ATOM 2461 O OP2   . DG  C 3 31  ? 131.528 131.582 139.908 1.00 105.29 ? -2  DG  C OP2   1 
ATOM 2462 O "O5'" . DG  C 3 31  ? 131.661 130.671 137.594 1.00 105.29 ? -2  DG  C "O5'" 1 
ATOM 2463 C "C5'" . DG  C 3 31  ? 132.118 129.338 137.807 1.00 105.29 ? -2  DG  C "C5'" 1 
ATOM 2464 C "C4'" . DG  C 3 31  ? 131.254 128.343 137.053 1.00 105.29 ? -2  DG  C "C4'" 1 
ATOM 2465 O "O4'" . DG  C 3 31  ? 130.260 129.060 136.275 1.00 105.29 ? -2  DG  C "O4'" 1 
ATOM 2466 C "C3'" . DG  C 3 31  ? 132.012 127.461 136.064 1.00 105.29 ? -2  DG  C "C3'" 1 
ATOM 2467 O "O3'" . DG  C 3 31  ? 132.324 126.213 136.672 1.00 105.29 ? -2  DG  C "O3'" 1 
ATOM 2468 C "C2'" . DG  C 3 31  ? 131.019 127.292 134.917 1.00 105.29 ? -2  DG  C "C2'" 1 
ATOM 2469 C "C1'" . DG  C 3 31  ? 130.282 128.624 134.932 1.00 105.29 ? -2  DG  C "C1'" 1 
ATOM 2470 N N9    . DG  C 3 31  ? 130.911 129.665 134.120 1.00 105.29 ? -2  DG  C N9    1 
ATOM 2471 C C8    . DG  C 3 31  ? 131.953 130.483 134.485 1.00 105.29 ? -2  DG  C C8    1 
ATOM 2472 N N7    . DG  C 3 31  ? 132.299 131.332 133.559 1.00 105.29 ? -2  DG  C N7    1 
ATOM 2473 C C5    . DG  C 3 31  ? 131.429 131.065 132.512 1.00 105.29 ? -2  DG  C C5    1 
ATOM 2474 C C6    . DG  C 3 31  ? 131.327 131.670 131.240 1.00 105.29 ? -2  DG  C C6    1 
ATOM 2475 O O6    . DG  C 3 31  ? 132.010 132.591 130.774 1.00 105.29 ? -2  DG  C O6    1 
ATOM 2476 N N1    . DG  C 3 31  ? 130.311 131.100 130.479 1.00 105.29 ? -2  DG  C N1    1 
ATOM 2477 C C2    . DG  C 3 31  ? 129.496 130.075 130.897 1.00 105.29 ? -2  DG  C C2    1 
ATOM 2478 N N2    . DG  C 3 31  ? 128.570 129.657 130.022 1.00 105.29 ? -2  DG  C N2    1 
ATOM 2479 N N3    . DG  C 3 31  ? 129.580 129.499 132.089 1.00 105.29 ? -2  DG  C N3    1 
ATOM 2480 C C4    . DG  C 3 31  ? 130.566 130.043 132.842 1.00 105.29 ? -2  DG  C C4    1 
ATOM 2481 P P     . DA  C 3 32  ? 133.500 125.294 136.077 1.00 104.43 ? -1  DA  C P     1 
ATOM 2482 O OP1   . DA  C 3 32  ? 133.830 124.272 137.095 1.00 104.43 ? -1  DA  C OP1   1 
ATOM 2483 O OP2   . DA  C 3 32  ? 134.558 126.193 135.566 1.00 104.43 ? -1  DA  C OP2   1 
ATOM 2484 O "O5'" . DA  C 3 32  ? 132.825 124.570 134.820 1.00 104.43 ? -1  DA  C "O5'" 1 
ATOM 2485 C "C5'" . DA  C 3 32  ? 131.685 123.737 135.007 1.00 104.43 ? -1  DA  C "C5'" 1 
ATOM 2486 C "C4'" . DA  C 3 32  ? 131.082 123.344 133.671 1.00 104.43 ? -1  DA  C "C4'" 1 
ATOM 2487 O "O4'" . DA  C 3 32  ? 130.484 124.510 133.047 1.00 104.43 ? -1  DA  C "O4'" 1 
ATOM 2488 C "C3'" . DA  C 3 32  ? 132.078 122.822 132.651 1.00 104.43 ? -1  DA  C "C3'" 1 
ATOM 2489 O "O3'" . DA  C 3 32  ? 132.268 121.424 132.821 1.00 104.43 ? -1  DA  C "O3'" 1 
ATOM 2490 C "C2'" . DA  C 3 32  ? 131.378 123.142 131.337 1.00 104.43 ? -1  DA  C "C2'" 1 
ATOM 2491 C "C1'" . DA  C 3 32  ? 130.745 124.496 131.652 1.00 104.43 ? -1  DA  C "C1'" 1 
ATOM 2492 N N9    . DA  C 3 32  ? 131.607 125.632 131.329 1.00 104.43 ? -1  DA  C N9    1 
ATOM 2493 C C8    . DA  C 3 32  ? 132.578 126.181 132.119 1.00 104.43 ? -1  DA  C C8    1 
ATOM 2494 N N7    . DA  C 3 32  ? 133.197 127.197 131.569 1.00 104.43 ? -1  DA  C N7    1 
ATOM 2495 C C5    . DA  C 3 32  ? 132.593 127.324 130.331 1.00 104.43 ? -1  DA  C C5    1 
ATOM 2496 C C6    . DA  C 3 32  ? 132.799 128.218 129.264 1.00 104.43 ? -1  DA  C C6    1 
ATOM 2497 N N6    . DA  C 3 32  ? 133.713 129.191 129.286 1.00 104.43 ? -1  DA  C N6    1 
ATOM 2498 N N1    . DA  C 3 32  ? 132.024 128.073 128.169 1.00 104.43 ? -1  DA  C N1    1 
ATOM 2499 C C2    . DA  C 3 32  ? 131.109 127.097 128.150 1.00 104.43 ? -1  DA  C C2    1 
ATOM 2500 N N3    . DA  C 3 32  ? 130.825 126.197 129.091 1.00 104.43 ? -1  DA  C N3    1 
ATOM 2501 C C4    . DA  C 3 32  ? 131.610 126.367 130.166 1.00 104.43 ? -1  DA  C C4    1 
ATOM 2502 P P     . DG  C 3 33  ? 133.756 120.820 132.877 1.00 91.11  ? 0   DG  C P     1 
ATOM 2503 O OP1   . DG  C 3 33  ? 134.662 121.832 132.290 1.00 91.11  ? 0   DG  C OP1   1 
ATOM 2504 O OP2   . DG  C 3 33  ? 133.712 119.462 132.291 1.00 91.11  ? 0   DG  C OP2   1 
ATOM 2505 O "O5'" . DG  C 3 33  ? 134.074 120.708 134.444 1.00 91.11  ? 0   DG  C "O5'" 1 
ATOM 2506 C "C5'" . DG  C 3 33  ? 133.354 119.787 135.266 1.00 91.11  ? 0   DG  C "C5'" 1 
ATOM 2507 C "C4'" . DG  C 3 33  ? 134.021 118.423 135.260 1.00 91.11  ? 0   DG  C "C4'" 1 
ATOM 2508 O "O4'" . DG  C 3 33  ? 134.288 118.001 136.620 1.00 91.11  ? 0   DG  C "O4'" 1 
ATOM 2509 C "C3'" . DG  C 3 33  ? 133.193 117.308 134.651 1.00 91.11  ? 0   DG  C "C3'" 1 
ATOM 2510 O "O3'" . DG  C 3 33  ? 134.050 116.308 134.129 1.00 91.11  ? 0   DG  C "O3'" 1 
ATOM 2511 C "C2'" . DG  C 3 33  ? 132.394 116.806 135.852 1.00 91.11  ? 0   DG  C "C2'" 1 
ATOM 2512 C "C1'" . DG  C 3 33  ? 133.389 116.972 137.000 1.00 91.11  ? 0   DG  C "C1'" 1 
ATOM 2513 N N9    . DG  C 3 33  ? 132.764 117.368 138.259 1.00 91.11  ? 0   DG  C N9    1 
ATOM 2514 C C8    . DG  C 3 33  ? 131.569 118.026 138.415 1.00 91.11  ? 0   DG  C C8    1 
ATOM 2515 N N7    . DG  C 3 33  ? 131.267 118.266 139.660 1.00 91.11  ? 0   DG  C N7    1 
ATOM 2516 C C5    . DG  C 3 33  ? 132.333 117.738 140.376 1.00 91.11  ? 0   DG  C C5    1 
ATOM 2517 C C6    . DG  C 3 33  ? 132.562 117.702 141.768 1.00 91.11  ? 0   DG  C C6    1 
ATOM 2518 O O6    . DG  C 3 33  ? 131.844 118.144 142.675 1.00 91.11  ? 0   DG  C O6    1 
ATOM 2519 N N1    . DG  C 3 33  ? 133.763 117.072 142.076 1.00 91.11  ? 0   DG  C N1    1 
ATOM 2520 C C2    . DG  C 3 33  ? 134.633 116.547 141.153 1.00 91.11  ? 0   DG  C C2    1 
ATOM 2521 N N2    . DG  C 3 33  ? 135.746 115.982 141.641 1.00 91.11  ? 0   DG  C N2    1 
ATOM 2522 N N3    . DG  C 3 33  ? 134.431 116.576 139.845 1.00 91.11  ? 0   DG  C N3    1 
ATOM 2523 C C4    . DG  C 3 33  ? 133.264 117.184 139.529 1.00 91.11  ? 0   DG  C C4    1 
ATOM 2524 P P     . DA  C 3 34  ? 133.448 114.952 133.516 1.00 84.58  ? 1   DA  C P     1 
ATOM 2525 O OP1   . DA  C 3 34  ? 134.318 114.562 132.386 1.00 84.58  ? 1   DA  C OP1   1 
ATOM 2526 O OP2   . DA  C 3 34  ? 131.997 115.127 133.288 1.00 84.58  ? 1   DA  C OP2   1 
ATOM 2527 O "O5'" . DA  C 3 34  ? 133.651 113.895 134.693 1.00 84.58  ? 1   DA  C "O5'" 1 
ATOM 2528 C "C5'" . DA  C 3 34  ? 134.955 113.649 135.196 1.00 84.58  ? 1   DA  C "C5'" 1 
ATOM 2529 C "C4'" . DA  C 3 34  ? 134.902 112.849 136.480 1.00 84.58  ? 1   DA  C "C4'" 1 
ATOM 2530 O "O4'" . DA  C 3 34  ? 134.115 113.566 137.464 1.00 84.58  ? 1   DA  C "O4'" 1 
ATOM 2531 C "C3'" . DA  C 3 34  ? 134.260 111.473 136.358 1.00 84.58  ? 1   DA  C "C3'" 1 
ATOM 2532 O "O3'" . DA  C 3 34  ? 134.880 110.580 137.262 1.00 84.58  ? 1   DA  C "O3'" 1 
ATOM 2533 C "C2'" . DA  C 3 34  ? 132.818 111.748 136.762 1.00 84.58  ? 1   DA  C "C2'" 1 
ATOM 2534 C "C1'" . DA  C 3 34  ? 133.018 112.774 137.866 1.00 84.58  ? 1   DA  C "C1'" 1 
ATOM 2535 N N9    . DA  C 3 34  ? 131.871 113.649 138.069 1.00 84.58  ? 1   DA  C N9    1 
ATOM 2536 C C8    . DA  C 3 34  ? 130.996 114.094 137.121 1.00 84.58  ? 1   DA  C C8    1 
ATOM 2537 N N7    . DA  C 3 34  ? 130.064 114.886 137.593 1.00 84.58  ? 1   DA  C N7    1 
ATOM 2538 C C5    . DA  C 3 34  ? 130.346 114.960 138.945 1.00 84.58  ? 1   DA  C C5    1 
ATOM 2539 C C6    . DA  C 3 34  ? 129.724 115.640 140.008 1.00 84.58  ? 1   DA  C C6    1 
ATOM 2540 N N6    . DA  C 3 34  ? 128.640 116.407 139.856 1.00 84.58  ? 1   DA  C N6    1 
ATOM 2541 N N1    . DA  C 3 34  ? 130.262 115.503 141.236 1.00 84.58  ? 1   DA  C N1    1 
ATOM 2542 C C2    . DA  C 3 34  ? 131.346 114.735 141.383 1.00 84.58  ? 1   DA  C C2    1 
ATOM 2543 N N3    . DA  C 3 34  ? 132.017 114.051 140.462 1.00 84.58  ? 1   DA  C N3    1 
ATOM 2544 C C4    . DA  C 3 34  ? 131.458 114.206 139.254 1.00 84.58  ? 1   DA  C C4    1 
ATOM 2545 P P     . DA  C 3 35  ? 135.676 109.298 136.716 1.00 88.77  ? 2   DA  C P     1 
ATOM 2546 O OP1   . DA  C 3 35  ? 136.608 109.759 135.665 1.00 88.77  ? 2   DA  C OP1   1 
ATOM 2547 O OP2   . DA  C 3 35  ? 134.678 108.251 136.409 1.00 88.77  ? 2   DA  C OP2   1 
ATOM 2548 O "O5'" . DA  C 3 35  ? 136.524 108.814 137.981 1.00 88.77  ? 2   DA  C "O5'" 1 
ATOM 2549 C "C5'" . DA  C 3 35  ? 137.502 109.674 138.552 1.00 88.77  ? 2   DA  C "C5'" 1 
ATOM 2550 C "C4'" . DA  C 3 35  ? 137.513 109.547 140.064 1.00 88.77  ? 2   DA  C "C4'" 1 
ATOM 2551 O "O4'" . DA  C 3 35  ? 136.491 110.409 140.629 1.00 88.77  ? 2   DA  C "O4'" 1 
ATOM 2552 C "C3'" . DA  C 3 35  ? 137.241 108.141 140.589 1.00 88.77  ? 2   DA  C "C3'" 1 
ATOM 2553 O "O3'" . DA  C 3 35  ? 138.172 107.802 141.603 1.00 88.77  ? 2   DA  C "O3'" 1 
ATOM 2554 C "C2'" . DA  C 3 35  ? 135.816 108.217 141.131 1.00 88.77  ? 2   DA  C "C2'" 1 
ATOM 2555 C "C1'" . DA  C 3 35  ? 135.674 109.683 141.515 1.00 88.77  ? 2   DA  C "C1'" 1 
ATOM 2556 N N9    . DA  C 3 35  ? 134.308 110.174 141.375 1.00 88.77  ? 2   DA  C N9    1 
ATOM 2557 C C8    . DA  C 3 35  ? 133.597 110.289 140.216 1.00 88.77  ? 2   DA  C C8    1 
ATOM 2558 N N7    . DA  C 3 35  ? 132.382 110.752 140.383 1.00 88.77  ? 2   DA  C N7    1 
ATOM 2559 C C5    . DA  C 3 35  ? 132.287 110.954 141.746 1.00 88.77  ? 2   DA  C C5    1 
ATOM 2560 C C6    . DA  C 3 35  ? 131.247 111.435 142.559 1.00 88.77  ? 2   DA  C C6    1 
ATOM 2561 N N6    . DA  C 3 35  ? 130.058 111.814 142.084 1.00 88.77  ? 2   DA  C N6    1 
ATOM 2562 N N1    . DA  C 3 35  ? 131.477 111.516 143.885 1.00 88.77  ? 2   DA  C N1    1 
ATOM 2563 C C2    . DA  C 3 35  ? 132.672 111.140 144.355 1.00 88.77  ? 2   DA  C C2    1 
ATOM 2564 N N3    . DA  C 3 35  ? 133.724 110.666 143.688 1.00 88.77  ? 2   DA  C N3    1 
ATOM 2565 C C4    . DA  C 3 35  ? 133.465 110.600 142.376 1.00 88.77  ? 2   DA  C C4    1 
ATOM 2566 P P     . DT  C 3 36  ? 138.147 106.336 142.259 1.00 97.11  ? 3   DT  C P     1 
ATOM 2567 O OP1   . DT  C 3 36  ? 139.519 106.025 142.715 1.00 97.11  ? 3   DT  C OP1   1 
ATOM 2568 O OP2   . DT  C 3 36  ? 137.465 105.427 141.311 1.00 97.11  ? 3   DT  C OP2   1 
ATOM 2569 O "O5'" . DT  C 3 36  ? 137.205 106.507 143.539 1.00 97.11  ? 3   DT  C "O5'" 1 
ATOM 2570 C "C5'" . DT  C 3 36  ? 137.523 107.484 144.521 1.00 97.11  ? 3   DT  C "C5'" 1 
ATOM 2571 C "C4'" . DT  C 3 36  ? 136.555 107.423 145.687 1.00 97.11  ? 3   DT  C "C4'" 1 
ATOM 2572 O "O4'" . DT  C 3 36  ? 135.319 108.097 145.339 1.00 97.11  ? 3   DT  C "O4'" 1 
ATOM 2573 C "C3'" . DT  C 3 36  ? 136.165 106.015 146.137 1.00 97.11  ? 3   DT  C "C3'" 1 
ATOM 2574 O "O3'" . DT  C 3 36  ? 136.234 105.938 147.557 1.00 97.11  ? 3   DT  C "O3'" 1 
ATOM 2575 C "C2'" . DT  C 3 36  ? 134.731 105.863 145.621 1.00 97.11  ? 3   DT  C "C2'" 1 
ATOM 2576 C "C1'" . DT  C 3 36  ? 134.224 107.290 145.700 1.00 97.11  ? 3   DT  C "C1'" 1 
ATOM 2577 N N1    . DT  C 3 36  ? 133.103 107.594 144.767 1.00 97.11  ? 3   DT  C N1    1 
ATOM 2578 C C2    . DT  C 3 36  ? 131.969 108.192 145.257 1.00 97.11  ? 3   DT  C C2    1 
ATOM 2579 O O2    . DT  C 3 36  ? 131.823 108.486 146.428 1.00 97.11  ? 3   DT  C O2    1 
ATOM 2580 N N3    . DT  C 3 36  ? 131.005 108.448 144.319 1.00 97.11  ? 3   DT  C N3    1 
ATOM 2581 C C4    . DT  C 3 36  ? 131.058 108.169 142.968 1.00 97.11  ? 3   DT  C C4    1 
ATOM 2582 O O4    . DT  C 3 36  ? 130.135 108.435 142.205 1.00 97.11  ? 3   DT  C O4    1 
ATOM 2583 C C5    . DT  C 3 36  ? 132.274 107.541 142.517 1.00 97.11  ? 3   DT  C C5    1 
ATOM 2584 C C7    . DT  C 3 36  ? 132.443 107.188 141.070 1.00 97.11  ? 3   DT  C C7    1 
ATOM 2585 C C6    . DT  C 3 36  ? 133.230 107.289 143.427 1.00 97.11  ? 3   DT  C C6    1 
ATOM 2586 P P     . DT  C 3 37  ? 135.757 104.615 148.335 1.00 103.15 ? 4   DT  C P     1 
ATOM 2587 O OP1   . DT  C 3 37  ? 136.607 104.489 149.539 1.00 103.15 ? 4   DT  C OP1   1 
ATOM 2588 O OP2   . DT  C 3 37  ? 135.691 103.492 147.374 1.00 103.15 ? 4   DT  C OP2   1 
ATOM 2589 O "O5'" . DT  C 3 37  ? 134.271 104.974 148.801 1.00 103.15 ? 4   DT  C "O5'" 1 
ATOM 2590 C "C5'" . DT  C 3 37  ? 134.028 106.181 149.519 1.00 103.15 ? 4   DT  C "C5'" 1 
ATOM 2591 C "C4'" . DT  C 3 37  ? 132.548 106.356 149.809 1.00 103.15 ? 4   DT  C "C4'" 1 
ATOM 2592 O "O4'" . DT  C 3 37  ? 131.848 106.720 148.589 1.00 103.15 ? 4   DT  C "O4'" 1 
ATOM 2593 C "C3'" . DT  C 3 37  ? 131.841 105.111 150.341 1.00 103.15 ? 4   DT  C "C3'" 1 
ATOM 2594 O "O3'" . DT  C 3 37  ? 130.890 105.484 151.321 1.00 103.15 ? 4   DT  C "O3'" 1 
ATOM 2595 C "C2'" . DT  C 3 37  ? 131.161 104.561 149.094 1.00 103.15 ? 4   DT  C "C2'" 1 
ATOM 2596 C "C1'" . DT  C 3 37  ? 130.755 105.852 148.411 1.00 103.15 ? 4   DT  C "C1'" 1 
ATOM 2597 N N1    . DT  C 3 37  ? 130.491 105.705 146.956 1.00 103.15 ? 4   DT  C N1    1 
ATOM 2598 C C2    . DT  C 3 37  ? 129.383 106.306 146.415 1.00 103.15 ? 4   DT  C C2    1 
ATOM 2599 O O2    . DT  C 3 37  ? 128.597 106.966 147.069 1.00 103.15 ? 4   DT  C O2    1 
ATOM 2600 N N3    . DT  C 3 37  ? 129.224 106.111 145.071 1.00 103.15 ? 4   DT  C N3    1 
ATOM 2601 C C4    . DT  C 3 37  ? 130.045 105.386 144.230 1.00 103.15 ? 4   DT  C C4    1 
ATOM 2602 O O4    . DT  C 3 37  ? 129.817 105.268 143.031 1.00 103.15 ? 4   DT  C O4    1 
ATOM 2603 C C5    . DT  C 3 37  ? 131.191 104.778 144.861 1.00 103.15 ? 4   DT  C C5    1 
ATOM 2604 C C7    . DT  C 3 37  ? 132.153 103.963 144.048 1.00 103.15 ? 4   DT  C C7    1 
ATOM 2605 C C6    . DT  C 3 37  ? 131.356 104.963 146.180 1.00 103.15 ? 4   DT  C C6    1 
ATOM 2606 P P     . DG  C 3 38  ? 130.967 104.861 152.799 1.00 117.89 ? 5   DG  C P     1 
ATOM 2607 O OP1   . DG  C 3 38  ? 131.624 105.857 153.673 1.00 117.89 ? 5   DG  C OP1   1 
ATOM 2608 O OP2   . DG  C 3 38  ? 131.525 103.496 152.689 1.00 117.89 ? 5   DG  C OP2   1 
ATOM 2609 O "O5'" . DG  C 3 38  ? 129.438 104.732 153.232 1.00 117.89 ? 5   DG  C "O5'" 1 
ATOM 2610 C "C5'" . DG  C 3 38  ? 128.629 105.890 153.313 1.00 117.89 ? 5   DG  C "C5'" 1 
ATOM 2611 C "C4'" . DG  C 3 38  ? 127.190 105.568 152.961 1.00 117.89 ? 5   DG  C "C4'" 1 
ATOM 2612 O "O4'" . DG  C 3 38  ? 127.001 105.674 151.523 1.00 117.89 ? 5   DG  C "O4'" 1 
ATOM 2613 C "C3'" . DG  C 3 38  ? 126.728 104.159 153.342 1.00 117.89 ? 5   DG  C "C3'" 1 
ATOM 2614 O "O3'" . DG  C 3 38  ? 125.391 104.207 153.824 1.00 117.89 ? 5   DG  C "O3'" 1 
ATOM 2615 C "C2'" . DG  C 3 38  ? 126.811 103.414 152.014 1.00 117.89 ? 5   DG  C "C2'" 1 
ATOM 2616 C "C1'" . DG  C 3 38  ? 126.370 104.505 151.057 1.00 117.89 ? 5   DG  C "C1'" 1 
ATOM 2617 N N9    . DG  C 3 38  ? 126.762 104.273 149.669 1.00 117.89 ? 5   DG  C N9    1 
ATOM 2618 C C8    . DG  C 3 38  ? 127.982 103.847 149.212 1.00 117.89 ? 5   DG  C C8    1 
ATOM 2619 N N7    . DG  C 3 38  ? 128.042 103.731 147.914 1.00 117.89 ? 5   DG  C N7    1 
ATOM 2620 C C5    . DG  C 3 38  ? 126.777 104.101 147.484 1.00 117.89 ? 5   DG  C C5    1 
ATOM 2621 C C6    . DG  C 3 38  ? 126.244 104.172 146.176 1.00 117.89 ? 5   DG  C C6    1 
ATOM 2622 O O6    . DG  C 3 38  ? 126.805 103.911 145.106 1.00 117.89 ? 5   DG  C O6    1 
ATOM 2623 N N1    . DG  C 3 38  ? 124.917 104.593 146.183 1.00 117.89 ? 5   DG  C N1    1 
ATOM 2624 C C2    . DG  C 3 38  ? 124.199 104.909 147.313 1.00 117.89 ? 5   DG  C C2    1 
ATOM 2625 N N2    . DG  C 3 38  ? 122.931 105.302 147.130 1.00 117.89 ? 5   DG  C N2    1 
ATOM 2626 N N3    . DG  C 3 38  ? 124.689 104.847 148.542 1.00 117.89 ? 5   DG  C N3    1 
ATOM 2627 C C4    . DG  C 3 38  ? 125.978 104.438 148.552 1.00 117.89 ? 5   DG  C C4    1 
ATOM 2628 P P     . DG  C 3 39  ? 124.808 103.026 154.745 1.00 131.76 ? 6   DG  C P     1 
ATOM 2629 O OP1   . DG  C 3 39  ? 124.742 103.536 156.132 1.00 131.76 ? 6   DG  C OP1   1 
ATOM 2630 O OP2   . DG  C 3 39  ? 125.570 101.791 154.454 1.00 131.76 ? 6   DG  C OP2   1 
ATOM 2631 O "O5'" . DG  C 3 39  ? 123.317 102.824 154.201 1.00 131.76 ? 6   DG  C "O5'" 1 
ATOM 2632 C "C5'" . DG  C 3 39  ? 122.384 103.898 154.270 1.00 131.76 ? 6   DG  C "C5'" 1 
ATOM 2633 C "C4'" . DG  C 3 39  ? 121.413 103.856 153.101 1.00 131.76 ? 6   DG  C "C4'" 1 
ATOM 2634 O "O4'" . DG  C 3 39  ? 122.156 103.864 151.851 1.00 131.76 ? 6   DG  C "O4'" 1 
ATOM 2635 C "C3'" . DG  C 3 39  ? 120.517 102.618 153.042 1.00 131.76 ? 6   DG  C "C3'" 1 
ATOM 2636 O "O3'" . DG  C 3 39  ? 119.228 102.978 152.552 1.00 131.76 ? 6   DG  C "O3'" 1 
ATOM 2637 C "C2'" . DG  C 3 39  ? 121.254 101.729 152.051 1.00 131.76 ? 6   DG  C "C2'" 1 
ATOM 2638 C "C1'" . DG  C 3 39  ? 121.755 102.763 151.066 1.00 131.76 ? 6   DG  C "C1'" 1 
ATOM 2639 N N9    . DG  C 3 39  ? 122.894 102.319 150.272 1.00 131.76 ? 6   DG  C N9    1 
ATOM 2640 C C8    . DG  C 3 39  ? 124.133 101.957 150.733 1.00 131.76 ? 6   DG  C C8    1 
ATOM 2641 N N7    . DG  C 3 39  ? 124.959 101.611 149.786 1.00 131.76 ? 6   DG  C N7    1 
ATOM 2642 C C5    . DG  C 3 39  ? 124.216 101.747 148.622 1.00 131.76 ? 6   DG  C C5    1 
ATOM 2643 C C6    . DG  C 3 39  ? 124.579 101.515 147.275 1.00 131.76 ? 6   DG  C C6    1 
ATOM 2644 O O6    . DG  C 3 39  ? 125.663 101.122 146.826 1.00 131.76 ? 6   DG  C O6    1 
ATOM 2645 N N1    . DG  C 3 39  ? 123.523 101.778 146.405 1.00 131.76 ? 6   DG  C N1    1 
ATOM 2646 C C2    . DG  C 3 39  ? 122.278 102.216 146.790 1.00 131.76 ? 6   DG  C C2    1 
ATOM 2647 N N2    . DG  C 3 39  ? 121.388 102.415 145.807 1.00 131.76 ? 6   DG  C N2    1 
ATOM 2648 N N3    . DG  C 3 39  ? 121.928 102.438 148.048 1.00 131.76 ? 6   DG  C N3    1 
ATOM 2649 C C4    . DG  C 3 39  ? 122.943 102.186 148.906 1.00 131.76 ? 6   DG  C C4    1 
ATOM 2650 P P     . DC  C 3 40  ? 117.985 101.973 152.719 1.00 155.94 ? 7   DC  C P     1 
ATOM 2651 O OP1   . DC  C 3 40  ? 116.751 102.739 152.438 1.00 155.94 ? 7   DC  C OP1   1 
ATOM 2652 O OP2   . DC  C 3 40  ? 118.141 101.279 154.016 1.00 155.94 ? 7   DC  C OP2   1 
ATOM 2653 O "O5'" . DC  C 3 40  ? 118.196 100.891 151.556 1.00 155.94 ? 7   DC  C "O5'" 1 
ATOM 2654 C "C5'" . DC  C 3 40  ? 117.998 101.255 150.191 1.00 155.94 ? 7   DC  C "C5'" 1 
ATOM 2655 C "C4'" . DC  C 3 40  ? 118.374 100.107 149.268 1.00 155.94 ? 7   DC  C "C4'" 1 
ATOM 2656 O "O4'" . DC  C 3 40  ? 119.808 99.997  149.221 1.00 155.94 ? 7   DC  C "O4'" 1 
ATOM 2657 C "C3'" . DC  C 3 40  ? 117.877 98.741  149.717 1.00 155.94 ? 7   DC  C "C3'" 1 
ATOM 2658 O "O3'" . DC  C 3 40  ? 116.601 98.475  149.138 1.00 155.94 ? 7   DC  C "O3'" 1 
ATOM 2659 C "C2'" . DC  C 3 40  ? 118.947 97.771  149.192 1.00 155.94 ? 7   DC  C "C2'" 1 
ATOM 2660 C "C1'" . DC  C 3 40  ? 120.184 98.657  148.988 1.00 155.94 ? 7   DC  C "C1'" 1 
ATOM 2661 N N1    . DC  C 3 40  ? 121.359 98.335  149.878 1.00 155.94 ? 7   DC  C N1    1 
ATOM 2662 C C2    . DC  C 3 40  ? 121.255 98.457  151.275 1.00 155.94 ? 7   DC  C C2    1 
ATOM 2663 O O2    . DC  C 3 40  ? 120.182 98.802  151.782 1.00 155.94 ? 7   DC  C O2    1 
ATOM 2664 N N3    . DC  C 3 40  ? 122.342 98.184  152.039 1.00 155.94 ? 7   DC  C N3    1 
ATOM 2665 C C4    . DC  C 3 40  ? 123.488 97.815  151.466 1.00 155.94 ? 7   DC  C C4    1 
ATOM 2666 N N4    . DC  C 3 40  ? 124.530 97.555  152.262 1.00 155.94 ? 7   DC  C N4    1 
ATOM 2667 C C5    . DC  C 3 40  ? 123.616 97.696  150.053 1.00 155.94 ? 7   DC  C C5    1 
ATOM 2668 C C6    . DC  C 3 40  ? 122.541 97.969  149.307 1.00 155.94 ? 7   DC  C C6    1 
ATOM 2669 P P     . DC  C 3 41  ? 115.262 98.639  150.014 1.00 169.38 ? 8   DC  C P     1 
ATOM 2670 O OP1   . DC  C 3 41  ? 115.117 100.064 150.379 1.00 169.38 ? 8   DC  C OP1   1 
ATOM 2671 O OP2   . DC  C 3 41  ? 115.293 97.607  151.073 1.00 169.38 ? 8   DC  C OP2   1 
ATOM 2672 O "O5'" . DC  C 3 41  ? 114.085 98.265  148.998 1.00 169.38 ? 8   DC  C "O5'" 1 
ATOM 2673 C "C5'" . DC  C 3 41  ? 113.591 96.934  148.939 1.00 169.38 ? 8   DC  C "C5'" 1 
ATOM 2674 C "C4'" . DC  C 3 41  ? 114.076 96.229  147.686 1.00 169.38 ? 8   DC  C "C4'" 1 
ATOM 2675 O "O4'" . DC  C 3 41  ? 115.529 96.178  147.690 1.00 169.38 ? 8   DC  C "O4'" 1 
ATOM 2676 C "C3'" . DC  C 3 41  ? 113.600 94.784  147.540 1.00 169.38 ? 8   DC  C "C3'" 1 
ATOM 2677 O "O3'" . DC  C 3 41  ? 113.276 94.508  146.180 1.00 169.38 ? 8   DC  C "O3'" 1 
ATOM 2678 C "C2'" . DC  C 3 41  ? 114.809 93.978  148.003 1.00 169.38 ? 8   DC  C "C2'" 1 
ATOM 2679 C "C1'" . DC  C 3 41  ? 115.954 94.846  147.507 1.00 169.38 ? 8   DC  C "C1'" 1 
ATOM 2680 N N1    . DC  C 3 41  ? 117.227 94.642  148.259 1.00 169.38 ? 8   DC  C N1    1 
ATOM 2681 C C2    . DC  C 3 41  ? 118.391 94.295  147.567 1.00 169.38 ? 8   DC  C C2    1 
ATOM 2682 O O2    . DC  C 3 41  ? 118.349 94.171  146.338 1.00 169.38 ? 8   DC  C O2    1 
ATOM 2683 N N3    . DC  C 3 41  ? 119.541 94.113  148.262 1.00 169.38 ? 8   DC  C N3    1 
ATOM 2684 C C4    . DC  C 3 41  ? 119.548 94.258  149.589 1.00 169.38 ? 8   DC  C C4    1 
ATOM 2685 N N4    . DC  C 3 41  ? 120.705 94.066  150.233 1.00 169.38 ? 8   DC  C N4    1 
ATOM 2686 C C5    . DC  C 3 41  ? 118.369 94.606  150.314 1.00 169.38 ? 8   DC  C C5    1 
ATOM 2687 C C6    . DC  C 3 41  ? 117.243 94.786  149.616 1.00 169.38 ? 8   DC  C C6    1 
ATOM 2688 P P     . DA  C 3 42  ? 111.984 93.620  145.822 1.00 174.46 ? 9   DA  C P     1 
ATOM 2689 O OP1   . DA  C 3 42  ? 110.985 94.513  145.196 1.00 174.46 ? 9   DA  C OP1   1 
ATOM 2690 O OP2   . DA  C 3 42  ? 111.622 92.847  147.031 1.00 174.46 ? 9   DA  C OP2   1 
ATOM 2691 O "O5'" . DA  C 3 42  ? 112.517 92.588  144.720 1.00 174.46 ? 9   DA  C "O5'" 1 
ATOM 2692 C "C5'" . DA  C 3 42  ? 112.818 93.042  143.404 1.00 174.46 ? 9   DA  C "C5'" 1 
ATOM 2693 C "C4'" . DA  C 3 42  ? 113.771 92.088  142.701 1.00 174.46 ? 9   DA  C "C4'" 1 
ATOM 2694 O "O4'" . DA  C 3 42  ? 115.031 92.041  143.420 1.00 174.46 ? 9   DA  C "O4'" 1 
ATOM 2695 C "C3'" . DA  C 3 42  ? 113.286 90.643  142.597 1.00 174.46 ? 9   DA  C "C3'" 1 
ATOM 2696 O "O3'" . DA  C 3 42  ? 113.661 90.094  141.340 1.00 174.46 ? 9   DA  C "O3'" 1 
ATOM 2697 C "C2'" . DA  C 3 42  ? 114.011 89.951  143.749 1.00 174.46 ? 9   DA  C "C2'" 1 
ATOM 2698 C "C1'" . DA  C 3 42  ? 115.330 90.710  143.788 1.00 174.46 ? 9   DA  C "C1'" 1 
ATOM 2699 N N9    . DA  C 3 42  ? 115.946 90.731  145.111 1.00 174.46 ? 9   DA  C N9    1 
ATOM 2700 C C8    . DA  C 3 42  ? 115.350 91.088  146.287 1.00 174.46 ? 9   DA  C C8    1 
ATOM 2701 N N7    . DA  C 3 42  ? 116.145 91.016  147.328 1.00 174.46 ? 9   DA  C N7    1 
ATOM 2702 C C5    . DA  C 3 42  ? 117.348 90.584  146.798 1.00 174.46 ? 9   DA  C C5    1 
ATOM 2703 C C6    . DA  C 3 42  ? 118.598 90.309  147.385 1.00 174.46 ? 9   DA  C C6    1 
ATOM 2704 N N6    . DA  C 3 42  ? 118.838 90.441  148.693 1.00 174.46 ? 9   DA  C N6    1 
ATOM 2705 N N1    . DA  C 3 42  ? 119.594 89.894  146.574 1.00 174.46 ? 9   DA  C N1    1 
ATOM 2706 C C2    . DA  C 3 42  ? 119.346 89.764  145.264 1.00 174.46 ? 9   DA  C C2    1 
ATOM 2707 N N3    . DA  C 3 42  ? 118.213 89.992  144.598 1.00 174.46 ? 9   DA  C N3    1 
ATOM 2708 C C4    . DA  C 3 42  ? 117.245 90.403  145.431 1.00 174.46 ? 9   DA  C C4    1 
ATOM 2709 P P     . DT  D 4 1   ? 128.336 88.038  149.986 1.00 170.94 ? -9  DT  D P     1 
ATOM 2710 O OP1   . DT  D 4 1   ? 129.076 89.246  150.414 1.00 170.94 ? -9  DT  D OP1   1 
ATOM 2711 O OP2   . DT  D 4 1   ? 127.166 87.573  150.764 1.00 170.94 ? -9  DT  D OP2   1 
ATOM 2712 O "O5'" . DT  D 4 1   ? 127.877 88.221  148.464 1.00 170.94 ? -9  DT  D "O5'" 1 
ATOM 2713 C "C5'" . DT  D 4 1   ? 128.083 87.169  147.527 1.00 170.94 ? -9  DT  D "C5'" 1 
ATOM 2714 C "C4'" . DT  D 4 1   ? 127.414 87.483  146.199 1.00 170.94 ? -9  DT  D "C4'" 1 
ATOM 2715 O "O4'" . DT  D 4 1   ? 125.982 87.620  146.395 1.00 170.94 ? -9  DT  D "O4'" 1 
ATOM 2716 C "C3'" . DT  D 4 1   ? 127.874 88.776  145.530 1.00 170.94 ? -9  DT  D "C3'" 1 
ATOM 2717 O "O3'" . DT  D 4 1   ? 127.918 88.601  144.120 1.00 170.94 ? -9  DT  D "O3'" 1 
ATOM 2718 C "C2'" . DT  D 4 1   ? 126.793 89.774  145.935 1.00 170.94 ? -9  DT  D "C2'" 1 
ATOM 2719 C "C1'" . DT  D 4 1   ? 125.553 88.891  145.951 1.00 170.94 ? -9  DT  D "C1'" 1 
ATOM 2720 N N1    . DT  D 4 1   ? 124.490 89.374  146.877 1.00 170.94 ? -9  DT  D N1    1 
ATOM 2721 C C2    . DT  D 4 1   ? 123.241 89.665  146.378 1.00 170.94 ? -9  DT  D C2    1 
ATOM 2722 O O2    . DT  D 4 1   ? 122.949 89.553  145.201 1.00 170.94 ? -9  DT  D O2    1 
ATOM 2723 N N3    . DT  D 4 1   ? 122.338 90.095  147.314 1.00 170.94 ? -9  DT  D N3    1 
ATOM 2724 C C4    . DT  D 4 1   ? 122.556 90.260  148.670 1.00 170.94 ? -9  DT  D C4    1 
ATOM 2725 O O4    . DT  D 4 1   ? 121.681 90.653  149.433 1.00 170.94 ? -9  DT  D O4    1 
ATOM 2726 C C5    . DT  D 4 1   ? 123.887 89.936  149.126 1.00 170.94 ? -9  DT  D C5    1 
ATOM 2727 C C7    . DT  D 4 1   ? 124.242 90.075  150.577 1.00 170.94 ? -9  DT  D C7    1 
ATOM 2728 C C6    . DT  D 4 1   ? 124.778 89.513  148.218 1.00 170.94 ? -9  DT  D C6    1 
ATOM 2729 P P     . DG  D 4 2   ? 128.943 89.461  143.230 1.00 163.49 ? -8  DG  D P     1 
ATOM 2730 O OP1   . DG  D 4 2   ? 130.077 88.578  142.878 1.00 163.49 ? -8  DG  D OP1   1 
ATOM 2731 O OP2   . DG  D 4 2   ? 129.198 90.737  143.934 1.00 163.49 ? -8  DG  D OP2   1 
ATOM 2732 O "O5'" . DG  D 4 2   ? 128.112 89.784  141.900 1.00 163.49 ? -8  DG  D "O5'" 1 
ATOM 2733 C "C5'" . DG  D 4 2   ? 126.689 89.827  141.943 1.00 163.49 ? -8  DG  D "C5'" 1 
ATOM 2734 C "C4'" . DG  D 4 2   ? 126.186 91.260  141.895 1.00 163.49 ? -8  DG  D "C4'" 1 
ATOM 2735 O "O4'" . DG  D 4 2   ? 125.444 91.550  143.094 1.00 163.49 ? -8  DG  D "O4'" 1 
ATOM 2736 C "C3'" . DG  D 4 2   ? 127.280 92.328  141.828 1.00 163.49 ? -8  DG  D "C3'" 1 
ATOM 2737 O "O3'" . DG  D 4 2   ? 127.454 92.850  140.480 1.00 163.49 ? -8  DG  D "O3'" 1 
ATOM 2738 C "C2'" . DG  D 4 2   ? 126.833 93.417  142.823 1.00 163.49 ? -8  DG  D "C2'" 1 
ATOM 2739 C "C1'" . DG  D 4 2   ? 125.458 92.938  143.288 1.00 163.49 ? -8  DG  D "C1'" 1 
ATOM 2740 N N9    . DG  D 4 2   ? 125.180 93.219  144.696 1.00 163.49 ? -8  DG  D N9    1 
ATOM 2741 C C8    . DG  D 4 2   ? 126.058 93.130  145.749 1.00 163.49 ? -8  DG  D C8    1 
ATOM 2742 N N7    . DG  D 4 2   ? 125.526 93.444  146.898 1.00 163.49 ? -8  DG  D N7    1 
ATOM 2743 C C5    . DG  D 4 2   ? 124.210 93.763  146.588 1.00 163.49 ? -8  DG  D C5    1 
ATOM 2744 C C6    . DG  D 4 2   ? 123.149 94.181  147.427 1.00 163.49 ? -8  DG  D C6    1 
ATOM 2745 O O6    . DG  D 4 2   ? 123.158 94.352  148.653 1.00 163.49 ? -8  DG  D O6    1 
ATOM 2746 N N1    . DG  D 4 2   ? 121.977 94.398  146.708 1.00 163.49 ? -8  DG  D N1    1 
ATOM 2747 C C2    . DG  D 4 2   ? 121.848 94.239  145.349 1.00 163.49 ? -8  DG  D C2    1 
ATOM 2748 N N2    . DG  D 4 2   ? 120.638 94.497  144.836 1.00 163.49 ? -8  DG  D N2    1 
ATOM 2749 N N3    . DG  D 4 2   ? 122.833 93.848  144.550 1.00 163.49 ? -8  DG  D N3    1 
ATOM 2750 C C4    . DG  D 4 2   ? 123.981 93.630  145.236 1.00 163.49 ? -8  DG  D C4    1 
ATOM 2751 P P     . DG  D 4 3   ? 126.244 92.956  139.416 1.00 155.85 ? -7  DG  D P     1 
ATOM 2752 O OP1   . DG  D 4 3   ? 125.894 91.608  138.913 1.00 155.85 ? -7  DG  D OP1   1 
ATOM 2753 O OP2   . DG  D 4 3   ? 126.660 93.982  138.436 1.00 155.85 ? -7  DG  D OP2   1 
ATOM 2754 O "O5'" . DG  D 4 3   ? 125.022 93.584  140.236 1.00 155.85 ? -7  DG  D "O5'" 1 
ATOM 2755 C "C5'" . DG  D 4 3   ? 123.700 93.505  139.710 1.00 155.85 ? -7  DG  D "C5'" 1 
ATOM 2756 C "C4'" . DG  D 4 3   ? 123.029 94.870  139.688 1.00 155.85 ? -7  DG  D "C4'" 1 
ATOM 2757 O "O4'" . DG  D 4 3   ? 122.806 95.332  141.047 1.00 155.85 ? -7  DG  D "O4'" 1 
ATOM 2758 C "C3'" . DG  D 4 3   ? 123.814 95.978  138.990 1.00 155.85 ? -7  DG  D "C3'" 1 
ATOM 2759 O "O3'" . DG  D 4 3   ? 122.913 96.829  138.298 1.00 155.85 ? -7  DG  D "O3'" 1 
ATOM 2760 C "C2'" . DG  D 4 3   ? 124.481 96.703  140.155 1.00 155.85 ? -7  DG  D "C2'" 1 
ATOM 2761 C "C1'" . DG  D 4 3   ? 123.411 96.595  141.230 1.00 155.85 ? -7  DG  D "C1'" 1 
ATOM 2762 N N9    . DG  D 4 3   ? 123.946 96.645  142.584 1.00 155.85 ? -7  DG  D N9    1 
ATOM 2763 C C8    . DG  D 4 3   ? 125.222 96.332  142.977 1.00 155.85 ? -7  DG  D C8    1 
ATOM 2764 N N7    . DG  D 4 3   ? 125.417 96.454  144.258 1.00 155.85 ? -7  DG  D N7    1 
ATOM 2765 C C5    . DG  D 4 3   ? 124.191 96.877  144.748 1.00 155.85 ? -7  DG  D C5    1 
ATOM 2766 C C6    . DG  D 4 3   ? 123.798 97.179  146.070 1.00 155.85 ? -7  DG  D C6    1 
ATOM 2767 O O6    . DG  D 4 3   ? 124.481 97.129  147.102 1.00 155.85 ? -7  DG  D O6    1 
ATOM 2768 N N1    . DG  D 4 3   ? 122.463 97.572  146.134 1.00 155.85 ? -7  DG  D N1    1 
ATOM 2769 C C2    . DG  D 4 3   ? 121.618 97.663  145.053 1.00 155.85 ? -7  DG  D C2    1 
ATOM 2770 N N2    . DG  D 4 3   ? 120.364 98.061  145.311 1.00 155.85 ? -7  DG  D N2    1 
ATOM 2771 N N3    . DG  D 4 3   ? 121.976 97.383  143.807 1.00 155.85 ? -7  DG  D N3    1 
ATOM 2772 C C4    . DG  D 4 3   ? 123.272 96.997  143.730 1.00 155.85 ? -7  DG  D C4    1 
ATOM 2773 P P     . DC  D 4 4   ? 123.435 97.822  137.147 1.00 144.03 ? -6  DC  D P     1 
ATOM 2774 O OP1   . DC  D 4 4   ? 123.022 97.249  135.847 1.00 144.03 ? -6  DC  D OP1   1 
ATOM 2775 O OP2   . DC  D 4 4   ? 124.862 98.128  137.392 1.00 144.03 ? -6  DC  D OP2   1 
ATOM 2776 O "O5'" . DC  D 4 4   ? 122.594 99.155  137.407 1.00 144.03 ? -6  DC  D "O5'" 1 
ATOM 2777 C "C5'" . DC  D 4 4   ? 121.190 99.069  137.612 1.00 144.03 ? -6  DC  D "C5'" 1 
ATOM 2778 C "C4'" . DC  D 4 4   ? 120.749 99.972  138.751 1.00 144.03 ? -6  DC  D "C4'" 1 
ATOM 2779 O "O4'" . DC  D 4 4   ? 121.417 99.580  139.974 1.00 144.03 ? -6  DC  D "O4'" 1 
ATOM 2780 C "C3'" . DC  D 4 4   ? 121.054 101.461 138.553 1.00 144.03 ? -6  DC  D "C3'" 1 
ATOM 2781 O "O3'" . DC  D 4 4   ? 119.848 102.210 138.601 1.00 144.03 ? -6  DC  D "O3'" 1 
ATOM 2782 C "C2'" . DC  D 4 4   ? 121.989 101.815 139.718 1.00 144.03 ? -6  DC  D "C2'" 1 
ATOM 2783 C "C1'" . DC  D 4 4   ? 121.670 100.731 140.733 1.00 144.03 ? -6  DC  D "C1'" 1 
ATOM 2784 N N1    . DC  D 4 4   ? 122.792 100.445 141.673 1.00 144.03 ? -6  DC  D N1    1 
ATOM 2785 C C2    . DC  D 4 4   ? 122.600 100.600 143.049 1.00 144.03 ? -6  DC  D C2    1 
ATOM 2786 O O2    . DC  D 4 4   ? 121.504 100.980 143.468 1.00 144.03 ? -6  DC  D O2    1 
ATOM 2787 N N3    . DC  D 4 4   ? 123.630 100.343 143.890 1.00 144.03 ? -6  DC  D N3    1 
ATOM 2788 C C4    . DC  D 4 4   ? 124.804 99.939  143.404 1.00 144.03 ? -6  DC  D C4    1 
ATOM 2789 N N4    . DC  D 4 4   ? 125.790 99.694  144.275 1.00 144.03 ? -6  DC  D N4    1 
ATOM 2790 C C5    . DC  D 4 4   ? 125.020 99.773  142.004 1.00 144.03 ? -6  DC  D C5    1 
ATOM 2791 C C6    . DC  D 4 4   ? 123.997 100.038 141.183 1.00 144.03 ? -6  DC  D C6    1 
ATOM 2792 P P     . DC  D 4 5   ? 119.772 103.671 137.937 1.00 126.90 ? -5  DC  D P     1 
ATOM 2793 O OP1   . DC  D 4 5   ? 118.665 103.660 136.955 1.00 126.90 ? -5  DC  D OP1   1 
ATOM 2794 O OP2   . DC  D 4 5   ? 121.136 104.046 137.502 1.00 126.90 ? -5  DC  D OP2   1 
ATOM 2795 O "O5'" . DC  D 4 5   ? 119.367 104.621 139.157 1.00 126.90 ? -5  DC  D "O5'" 1 
ATOM 2796 C "C5'" . DC  D 4 5   ? 118.213 104.323 139.933 1.00 126.90 ? -5  DC  D "C5'" 1 
ATOM 2797 C "C4'" . DC  D 4 5   ? 118.245 105.058 141.262 1.00 126.90 ? -5  DC  D "C4'" 1 
ATOM 2798 O "O4'" . DC  D 4 5   ? 119.369 104.588 142.053 1.00 126.90 ? -5  DC  D "O4'" 1 
ATOM 2799 C "C3'" . DC  D 4 5   ? 118.404 106.573 141.160 1.00 126.90 ? -5  DC  D "C3'" 1 
ATOM 2800 O "O3'" . DC  D 4 5   ? 117.611 107.208 142.155 1.00 126.90 ? -5  DC  D "O3'" 1 
ATOM 2801 C "C2'" . DC  D 4 5   ? 119.895 106.778 141.416 1.00 126.90 ? -5  DC  D "C2'" 1 
ATOM 2802 C "C1'" . DC  D 4 5   ? 120.179 105.680 142.430 1.00 126.90 ? -5  DC  D "C1'" 1 
ATOM 2803 N N1    . DC  D 4 5   ? 121.599 105.226 142.441 1.00 126.90 ? -5  DC  D N1    1 
ATOM 2804 C C2    . DC  D 4 5   ? 122.268 105.072 143.661 1.00 126.90 ? -5  DC  D C2    1 
ATOM 2805 O O2    . DC  D 4 5   ? 121.663 105.321 144.709 1.00 126.90 ? -5  DC  D O2    1 
ATOM 2806 N N3    . DC  D 4 5   ? 123.557 104.650 143.654 1.00 126.90 ? -5  DC  D N3    1 
ATOM 2807 C C4    . DC  D 4 5   ? 124.167 104.392 142.497 1.00 126.90 ? -5  DC  D C4    1 
ATOM 2808 N N4    . DC  D 4 5   ? 125.438 103.979 142.534 1.00 126.90 ? -5  DC  D N4    1 
ATOM 2809 C C5    . DC  D 4 5   ? 123.502 104.544 141.245 1.00 126.90 ? -5  DC  D C5    1 
ATOM 2810 C C6    . DC  D 4 5   ? 122.231 104.957 141.264 1.00 126.90 ? -5  DC  D C6    1 
ATOM 2811 P P     . DA  D 4 6   ? 116.824 108.567 141.817 1.00 112.29 ? -4  DA  D P     1 
ATOM 2812 O OP1   . DA  D 4 6   ? 115.384 108.322 142.051 1.00 112.29 ? -4  DA  D OP1   1 
ATOM 2813 O OP2   . DA  D 4 6   ? 117.286 109.036 140.492 1.00 112.29 ? -4  DA  D OP2   1 
ATOM 2814 O "O5'" . DA  D 4 6   ? 117.358 109.598 142.915 1.00 112.29 ? -4  DA  D "O5'" 1 
ATOM 2815 C "C5'" . DA  D 4 6   ? 118.756 109.783 143.090 1.00 112.29 ? -4  DA  D "C5'" 1 
ATOM 2816 C "C4'" . DA  D 4 6   ? 119.159 109.539 144.532 1.00 112.29 ? -4  DA  D "C4'" 1 
ATOM 2817 O "O4'" . DA  D 4 6   ? 120.194 108.522 144.576 1.00 112.29 ? -4  DA  D "O4'" 1 
ATOM 2818 C "C3'" . DA  D 4 6   ? 119.737 110.753 145.241 1.00 112.29 ? -4  DA  D "C3'" 1 
ATOM 2819 O "O3'" . DA  D 4 6   ? 119.401 110.737 146.617 1.00 112.29 ? -4  DA  D "O3'" 1 
ATOM 2820 C "C2'" . DA  D 4 6   ? 121.236 110.594 145.029 1.00 112.29 ? -4  DA  D "C2'" 1 
ATOM 2821 C "C1'" . DA  D 4 6   ? 121.410 109.078 145.039 1.00 112.29 ? -4  DA  D "C1'" 1 
ATOM 2822 N N9    . DA  D 4 6   ? 122.487 108.628 144.164 1.00 112.29 ? -4  DA  D N9    1 
ATOM 2823 C C8    . DA  D 4 6   ? 122.464 108.564 142.799 1.00 112.29 ? -4  DA  D C8    1 
ATOM 2824 N N7    . DA  D 4 6   ? 123.583 108.129 142.271 1.00 112.29 ? -4  DA  D N7    1 
ATOM 2825 C C5    . DA  D 4 6   ? 124.398 107.896 143.366 1.00 112.29 ? -4  DA  D C5    1 
ATOM 2826 C C6    . DA  D 4 6   ? 125.719 107.424 143.480 1.00 112.29 ? -4  DA  D C6    1 
ATOM 2827 N N6    . DA  D 4 6   ? 126.476 107.091 142.429 1.00 112.29 ? -4  DA  D N6    1 
ATOM 2828 N N1    . DA  D 4 6   ? 126.236 107.307 144.720 1.00 112.29 ? -4  DA  D N1    1 
ATOM 2829 C C2    . DA  D 4 6   ? 125.475 107.639 145.768 1.00 112.29 ? -4  DA  D C2    1 
ATOM 2830 N N3    . DA  D 4 6   ? 124.223 108.096 145.784 1.00 112.29 ? -4  DA  D N3    1 
ATOM 2831 C C4    . DA  D 4 6   ? 123.740 108.203 144.540 1.00 112.29 ? -4  DA  D C4    1 
ATOM 2832 P P     . DA  D 4 7   ? 119.600 112.067 147.496 1.00 93.92  ? -3  DA  D P     1 
ATOM 2833 O OP1   . DA  D 4 7   ? 118.647 112.016 148.626 1.00 93.92  ? -3  DA  D OP1   1 
ATOM 2834 O OP2   . DA  D 4 7   ? 119.577 113.211 146.560 1.00 93.92  ? -3  DA  D OP2   1 
ATOM 2835 O "O5'" . DA  D 4 7   ? 121.089 111.939 148.063 1.00 93.92  ? -3  DA  D "O5'" 1 
ATOM 2836 C "C5'" . DA  D 4 7   ? 121.374 111.025 149.113 1.00 93.92  ? -3  DA  D "C5'" 1 
ATOM 2837 C "C4'" . DA  D 4 7   ? 122.847 111.058 149.479 1.00 93.92  ? -3  DA  D "C4'" 1 
ATOM 2838 O "O4'" . DA  D 4 7   ? 123.630 110.452 148.417 1.00 93.92  ? -3  DA  D "O4'" 1 
ATOM 2839 C "C3'" . DA  D 4 7   ? 123.434 112.459 149.697 1.00 93.92  ? -3  DA  D "C3'" 1 
ATOM 2840 O "O3'" . DA  D 4 7   ? 124.151 112.500 150.920 1.00 93.92  ? -3  DA  D "O3'" 1 
ATOM 2841 C "C2'" . DA  D 4 7   ? 124.360 112.650 148.497 1.00 93.92  ? -3  DA  D "C2'" 1 
ATOM 2842 C "C1'" . DA  D 4 7   ? 124.785 111.224 148.213 1.00 93.92  ? -3  DA  D "C1'" 1 
ATOM 2843 N N9    . DA  D 4 7   ? 125.259 111.016 146.847 1.00 93.92  ? -3  DA  D N9    1 
ATOM 2844 C C8    . DA  D 4 7   ? 124.547 111.174 145.692 1.00 93.92  ? -3  DA  D C8    1 
ATOM 2845 N N7    . DA  D 4 7   ? 125.241 110.927 144.606 1.00 93.92  ? -3  DA  D N7    1 
ATOM 2846 C C5    . DA  D 4 7   ? 126.494 110.584 145.083 1.00 93.92  ? -3  DA  D C5    1 
ATOM 2847 C C6    . DA  D 4 7   ? 127.685 110.204 144.436 1.00 93.92  ? -3  DA  D C6    1 
ATOM 2848 N N6    . DA  D 4 7   ? 127.804 110.111 143.108 1.00 93.92  ? -3  DA  D N6    1 
ATOM 2849 N N1    . DA  D 4 7   ? 128.755 109.925 145.209 1.00 93.92  ? -3  DA  D N1    1 
ATOM 2850 C C2    . DA  D 4 7   ? 128.631 110.021 146.536 1.00 93.92  ? -3  DA  D C2    1 
ATOM 2851 N N3    . DA  D 4 7   ? 127.566 110.363 147.255 1.00 93.92  ? -3  DA  D N3    1 
ATOM 2852 C C4    . DA  D 4 7   ? 126.522 110.633 146.461 1.00 93.92  ? -3  DA  D C4    1 
ATOM 2853 P P     . DT  D 4 8   ? 124.781 113.882 151.443 1.00 88.57  ? -2  DT  D P     1 
ATOM 2854 O OP1   . DT  D 4 8   ? 124.544 113.954 152.900 1.00 88.57  ? -2  DT  D OP1   1 
ATOM 2855 O OP2   . DT  D 4 8   ? 124.291 114.968 150.568 1.00 88.57  ? -2  DT  D OP2   1 
ATOM 2856 O "O5'" . DT  D 4 8   ? 126.350 113.711 151.186 1.00 88.57  ? -2  DT  D "O5'" 1 
ATOM 2857 C "C5'" . DT  D 4 8   ? 127.060 112.667 151.836 1.00 88.57  ? -2  DT  D "C5'" 1 
ATOM 2858 C "C4'" . DT  D 4 8   ? 128.505 112.608 151.367 1.00 88.57  ? -2  DT  D "C4'" 1 
ATOM 2859 O "O4'" . DT  D 4 8   ? 128.558 112.269 149.954 1.00 88.57  ? -2  DT  D "O4'" 1 
ATOM 2860 C "C3'" . DT  D 4 8   ? 129.301 113.912 151.513 1.00 88.57  ? -2  DT  D "C3'" 1 
ATOM 2861 O "O3'" . DT  D 4 8   ? 130.606 113.615 152.002 1.00 88.57  ? -2  DT  D "O3'" 1 
ATOM 2862 C "C2'" . DT  D 4 8   ? 129.352 114.428 150.078 1.00 88.57  ? -2  DT  D "C2'" 1 
ATOM 2863 C "C1'" . DT  D 4 8   ? 129.490 113.119 149.336 1.00 88.57  ? -2  DT  D "C1'" 1 
ATOM 2864 N N1    . DT  D 4 8   ? 129.197 113.200 147.881 1.00 88.57  ? -2  DT  D N1    1 
ATOM 2865 C C2    . DT  D 4 8   ? 130.205 112.930 146.990 1.00 88.57  ? -2  DT  D C2    1 
ATOM 2866 O O2    . DT  D 4 8   ? 131.333 112.624 147.332 1.00 88.57  ? -2  DT  D O2    1 
ATOM 2867 N N3    . DT  D 4 8   ? 129.847 113.022 145.675 1.00 88.57  ? -2  DT  D N3    1 
ATOM 2868 C C4    . DT  D 4 8   ? 128.606 113.358 145.173 1.00 88.57  ? -2  DT  D C4    1 
ATOM 2869 O O4    . DT  D 4 8   ? 128.381 113.416 143.970 1.00 88.57  ? -2  DT  D O4    1 
ATOM 2870 C C5    . DT  D 4 8   ? 127.594 113.631 146.161 1.00 88.57  ? -2  DT  D C5    1 
ATOM 2871 C C7    . DT  D 4 8   ? 126.212 114.010 145.731 1.00 88.57  ? -2  DT  D C7    1 
ATOM 2872 C C6    . DT  D 4 8   ? 127.933 113.538 147.454 1.00 88.57  ? -2  DT  D C6    1 
ATOM 2873 P P     . DT  D 4 9   ? 131.605 114.787 152.463 1.00 90.65  ? -1  DT  D P     1 
ATOM 2874 O OP1   . DT  D 4 9   ? 131.939 114.538 153.881 1.00 90.65  ? -1  DT  D OP1   1 
ATOM 2875 O OP2   . DT  D 4 9   ? 131.031 116.093 152.072 1.00 90.65  ? -1  DT  D OP2   1 
ATOM 2876 O "O5'" . DT  D 4 9   ? 132.919 114.539 151.583 1.00 90.65  ? -1  DT  D "O5'" 1 
ATOM 2877 C "C5'" . DT  D 4 9   ? 132.828 114.480 150.165 1.00 90.65  ? -1  DT  D "C5'" 1 
ATOM 2878 C "C4'" . DT  D 4 9   ? 134.197 114.633 149.524 1.00 90.65  ? -1  DT  D "C4'" 1 
ATOM 2879 O "O4'" . DT  D 4 9   ? 134.084 114.446 148.093 1.00 90.65  ? -1  DT  D "O4'" 1 
ATOM 2880 C "C3'" . DT  D 4 9   ? 134.847 115.993 149.714 1.00 90.65  ? -1  DT  D "C3'" 1 
ATOM 2881 O "O3'" . DT  D 4 9   ? 136.259 115.859 149.789 1.00 90.65  ? -1  DT  D "O3'" 1 
ATOM 2882 C "C2'" . DT  D 4 9   ? 134.414 116.772 148.472 1.00 90.65  ? -1  DT  D "C2'" 1 
ATOM 2883 C "C1'" . DT  D 4 9   ? 134.229 115.681 147.416 1.00 90.65  ? -1  DT  D "C1'" 1 
ATOM 2884 N N1    . DT  D 4 9   ? 133.026 115.889 146.576 1.00 90.65  ? -1  DT  D N1    1 
ATOM 2885 C C2    . DT  D 4 9   ? 133.133 115.812 145.210 1.00 90.65  ? -1  DT  D C2    1 
ATOM 2886 O O2    . DT  D 4 9   ? 134.176 115.569 144.633 1.00 90.65  ? -1  DT  D O2    1 
ATOM 2887 N N3    . DT  D 4 9   ? 131.965 116.023 144.535 1.00 90.65  ? -1  DT  D N3    1 
ATOM 2888 C C4    . DT  D 4 9   ? 130.726 116.300 145.076 1.00 90.65  ? -1  DT  D C4    1 
ATOM 2889 O O4    . DT  D 4 9   ? 129.731 116.476 144.381 1.00 90.65  ? -1  DT  D O4    1 
ATOM 2890 C C5    . DT  D 4 9   ? 130.683 116.369 146.512 1.00 90.65  ? -1  DT  D C5    1 
ATOM 2891 C C7    . DT  D 4 9   ? 129.394 116.670 147.213 1.00 90.65  ? -1  DT  D C7    1 
ATOM 2892 C C6    . DT  D 4 9   ? 131.822 116.165 147.185 1.00 90.65  ? -1  DT  D C6    1 
ATOM 2893 P P     . DC  D 4 10  ? 137.114 116.529 150.997 1.00 94.59  ? 0   DC  D P     1 
ATOM 2894 O OP1   . DC  D 4 10  ? 137.070 115.615 152.169 1.00 94.59  ? 0   DC  D OP1   1 
ATOM 2895 O OP2   . DC  D 4 10  ? 136.722 117.960 151.150 1.00 94.59  ? 0   DC  D OP2   1 
ATOM 2896 O "O5'" . DC  D 4 10  ? 138.597 116.531 150.414 1.00 94.59  ? 0   DC  D "O5'" 1 
ATOM 2897 C "C5'" . DC  D 4 10  ? 139.250 117.771 150.087 1.00 94.59  ? 0   DC  D "C5'" 1 
ATOM 2898 C "C4'" . DC  D 4 10  ? 139.393 117.915 148.590 1.00 94.59  ? 0   DC  D "C4'" 1 
ATOM 2899 O "O4'" . DC  D 4 10  ? 138.109 117.743 147.956 1.00 94.59  ? 0   DC  D "O4'" 1 
ATOM 2900 C "C3'" . DC  D 4 10  ? 139.881 119.289 148.135 1.00 94.59  ? 0   DC  D "C3'" 1 
ATOM 2901 O "O3'" . DC  D 4 10  ? 141.299 119.298 147.952 1.00 94.59  ? 0   DC  D "O3'" 1 
ATOM 2902 C "C2'" . DC  D 4 10  ? 139.191 119.500 146.796 1.00 94.59  ? 0   DC  D "C2'" 1 
ATOM 2903 C "C1'" . DC  D 4 10  ? 138.164 118.378 146.690 1.00 94.59  ? 0   DC  D "C1'" 1 
ATOM 2904 N N1    . DC  D 4 10  ? 136.797 118.780 146.297 1.00 94.59  ? 0   DC  D N1    1 
ATOM 2905 C C2    . DC  D 4 10  ? 136.007 119.565 147.152 1.00 94.59  ? 0   DC  D C2    1 
ATOM 2906 O O2    . DC  D 4 10  ? 136.460 119.903 148.256 1.00 94.59  ? 0   DC  D O2    1 
ATOM 2907 N N3    . DC  D 4 10  ? 134.762 119.918 146.759 1.00 94.59  ? 0   DC  D N3    1 
ATOM 2908 C C4    . DC  D 4 10  ? 134.304 119.535 145.565 1.00 94.59  ? 0   DC  D C4    1 
ATOM 2909 N N4    . DC  D 4 10  ? 133.072 119.911 145.217 1.00 94.59  ? 0   DC  D N4    1 
ATOM 2910 C C5    . DC  D 4 10  ? 135.093 118.755 144.671 1.00 94.59  ? 0   DC  D C5    1 
ATOM 2911 C C6    . DC  D 4 10  ? 136.319 118.402 145.074 1.00 94.59  ? 0   DC  D C6    1 
ATOM 2912 P P     . DT  D 4 11  ? 142.152 120.574 148.405 1.00 104.29 ? 1   DT  D P     1 
ATOM 2913 O OP1   . DT  D 4 11  ? 142.926 120.201 149.615 1.00 104.29 ? 1   DT  D OP1   1 
ATOM 2914 O OP2   . DT  D 4 11  ? 141.241 121.746 148.448 1.00 104.29 ? 1   DT  D OP2   1 
ATOM 2915 O "O5'" . DT  D 4 11  ? 143.173 120.777 147.199 1.00 104.29 ? 1   DT  D "O5'" 1 
ATOM 2916 C "C5'" . DT  D 4 11  ? 143.077 119.993 145.994 1.00 104.29 ? 1   DT  D "C5'" 1 
ATOM 2917 C "C4'" . DT  D 4 11  ? 142.737 120.882 144.821 1.00 104.29 ? 1   DT  D "C4'" 1 
ATOM 2918 O "O4'" . DT  D 4 11  ? 141.344 120.718 144.489 1.00 104.29 ? 1   DT  D "O4'" 1 
ATOM 2919 C "C3'" . DT  D 4 11  ? 142.911 122.374 145.085 1.00 104.29 ? 1   DT  D "C3'" 1 
ATOM 2920 O "O3'" . DT  D 4 11  ? 144.225 122.796 144.706 1.00 104.29 ? 1   DT  D "O3'" 1 
ATOM 2921 C "C2'" . DT  D 4 11  ? 141.862 123.019 144.193 1.00 104.29 ? 1   DT  D "C2'" 1 
ATOM 2922 C "C1'" . DT  D 4 11  ? 140.844 121.914 143.909 1.00 104.29 ? 1   DT  D "C1'" 1 
ATOM 2923 N N1    . DT  D 4 11  ? 139.502 122.160 144.468 1.00 20.00  ? 1   DT  D N1    1 
ATOM 2924 C C2    . DT  D 4 11  ? 138.422 121.582 143.842 1.00 20.00  ? 1   DT  D C2    1 
ATOM 2925 O O2    . DT  D 4 11  ? 138.524 120.879 142.850 1.00 20.00  ? 1   DT  D O2    1 
ATOM 2926 N N3    . DT  D 4 11  ? 137.210 121.857 144.424 1.00 20.00  ? 1   DT  D N3    1 
ATOM 2927 C C4    . DT  D 4 11  ? 136.978 122.635 145.542 1.00 20.00  ? 1   DT  D C4    1 
ATOM 2928 O O4    . DT  D 4 11  ? 135.830 122.794 145.949 1.00 20.00  ? 1   DT  D O4    1 
ATOM 2929 C C5    . DT  D 4 11  ? 138.157 123.208 146.149 1.00 20.00  ? 1   DT  D C5    1 
ATOM 2930 C C7    . DT  D 4 11  ? 138.004 124.065 147.365 1.00 20.00  ? 1   DT  D C7    1 
ATOM 2931 C C6    . DT  D 4 11  ? 139.343 122.948 145.586 1.00 20.00  ? 1   DT  D C6    1 
# 
