data_8WS5
# 
_entry.id   8WS5 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8WS5         pdb_00008ws5 10.2210/pdb8ws5/pdb 
WWPDB D_1300041561 ?            ?                   
EMDB  EMD-37798    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-04-16 ? 
2 'EM metadata'     1 0 2025-04-16 ? 
3 'Half map'        1 0 2025-04-16 1 
4 'Half map'        1 0 2025-04-16 2 
5 Image             1 0 2025-04-16 ? 
6 'Primary map'     1 0 2025-04-16 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Half map'        repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 Image             repository 'Initial release' ? ? 
6 6 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8WS5 
_pdbx_database_status.recvd_initial_deposition_date   2023-10-16 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure of Cas12-1-N2/crRNA/Target DNA complex' 
_pdbx_database_related.db_id          EMD-37798 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 3 
_pdbx_contact_author.email              zhangk@sustech.edu.cn 
_pdbx_contact_author.name_first         Zhang 
_pdbx_contact_author.name_last          Kuo 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-2875-2581 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Kuo, Z.' 1 ? 
'Xi, Z.'  2 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Cryo-EM structure of Cas12-1-N2/crRNA/Target DNA complex' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Kuo, Z.' 1 ? 
primary 'Xi, Z.'  2 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man Cas12-1-N2 33550.656 1 ? ? ? ? 
2 polymer man TS         12941.301 1 ? ? ? ? 
3 polymer man crRNA      14652.684 1 ? ? ? ? 
4 polymer man NTS        12923.272 1 ? ? ? ? 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)'        no no 
;FCPPAKVNILAQSRPLSEWPINLVSKGVQEYVYGLTAAEREANGDFGTSRKSLDRWFARTGVPTHGYTTVQGLNLILRHT
FNRYDGVIKKVETRNEKRRSKATRINVSREADGLPPIEAEPEETAFGPDGKLKERPGINPSIYCYQQVSPVPYNPAKHPA
LPFSGVDPGAPLPLGTPNRLSIPKGQPGYVPEWQRPHLSTKNKRIRKWYARANWRRKPGRKSVLDEAKLKEAALKEAIPI
IVTIGKDWIVMDARGLLRAVYWRGIAKPGLSLKELLGFFSGDPVLDPKRGIATFTFKLGA
;
;FCPPAKVNILAQSRPLSEWPINLVSKGVQEYVYGLTAAEREANGDFGTSRKSLDRWFARTGVPTHGYTTVQGLNLILRHT
FNRYDGVIKKVETRNEKRRSKATRINVSREADGLPPIEAEPEETAFGPDGKLKERPGINPSIYCYQQVSPVPYNPAKHPA
LPFSGVDPGAPLPLGTPNRLSIPKGQPGYVPEWQRPHLSTKNKRIRKWYARANWRRKPGRKSVLDEAKLKEAALKEAIPI
IVTIGKDWIVMDARGLLRAVYWRGIAKPGLSLKELLGFFSGDPVLDPKRGIATFTFKLGA
;
A ? 
2 polydeoxyribonucleotide no no 
;(DC)(DT)(DG)(DC)(DC)(DC)(DT)(DT)(DG)(DC)(DA)(DA)(DC)(DT)(DT)(DC)(DA)(DG)(DC)(DA)
(DG)(DC)(DA)(DC)(DG)(DT)(DA)(DG)(DG)(DG)(DG)(DA)(DG)(DA)(DA)(DT)(DT)(DG)(DG)(DC)
(DC)(DA)
;
CTGCCCTTGCAACTTCAGCAGCACGTAGGGGAGAATTGGCCA C ? 
3 polyribonucleotide      no no UCAACGCUUGCUCGGUUCGCCGAGACUCCCCUACGUGCUGCUGAAG UCAACGCUUGCUCGGUUCGCCGAGACUCCCCUACGUGCUGCUGAAG B ? 
4 polydeoxyribonucleotide no no 
;(DT)(DG)(DG)(DC)(DC)(DA)(DA)(DT)(DT)(DC)(DT)(DC)(DC)(DC)(DC)(DT)(DA)(DC)(DG)(DT)
(DG)(DC)(DT)(DG)(DC)(DT)(DG)(DA)(DA)(DG)(DT)(DT)(DG)(DC)(DA)(DA)(DG)(DG)(DG)(DC)
(DA)(DG)
;
TGGCCAATTCTCCCCTACGTGCTGCTGAAGTTGCAAGGGCAG D ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   PHE n 
1 2   CYS n 
1 3   PRO n 
1 4   PRO n 
1 5   ALA n 
1 6   LYS n 
1 7   VAL n 
1 8   ASN n 
1 9   ILE n 
1 10  LEU n 
1 11  ALA n 
1 12  GLN n 
1 13  SER n 
1 14  ARG n 
1 15  PRO n 
1 16  LEU n 
1 17  SER n 
1 18  GLU n 
1 19  TRP n 
1 20  PRO n 
1 21  ILE n 
1 22  ASN n 
1 23  LEU n 
1 24  VAL n 
1 25  SER n 
1 26  LYS n 
1 27  GLY n 
1 28  VAL n 
1 29  GLN n 
1 30  GLU n 
1 31  TYR n 
1 32  VAL n 
1 33  TYR n 
1 34  GLY n 
1 35  LEU n 
1 36  THR n 
1 37  ALA n 
1 38  ALA n 
1 39  GLU n 
1 40  ARG n 
1 41  GLU n 
1 42  ALA n 
1 43  ASN n 
1 44  GLY n 
1 45  ASP n 
1 46  PHE n 
1 47  GLY n 
1 48  THR n 
1 49  SER n 
1 50  ARG n 
1 51  LYS n 
1 52  SER n 
1 53  LEU n 
1 54  ASP n 
1 55  ARG n 
1 56  TRP n 
1 57  PHE n 
1 58  ALA n 
1 59  ARG n 
1 60  THR n 
1 61  GLY n 
1 62  VAL n 
1 63  PRO n 
1 64  THR n 
1 65  HIS n 
1 66  GLY n 
1 67  TYR n 
1 68  THR n 
1 69  THR n 
1 70  VAL n 
1 71  GLN n 
1 72  GLY n 
1 73  LEU n 
1 74  ASN n 
1 75  LEU n 
1 76  ILE n 
1 77  LEU n 
1 78  ARG n 
1 79  HIS n 
1 80  THR n 
1 81  PHE n 
1 82  ASN n 
1 83  ARG n 
1 84  TYR n 
1 85  ASP n 
1 86  GLY n 
1 87  VAL n 
1 88  ILE n 
1 89  LYS n 
1 90  LYS n 
1 91  VAL n 
1 92  GLU n 
1 93  THR n 
1 94  ARG n 
1 95  ASN n 
1 96  GLU n 
1 97  LYS n 
1 98  ARG n 
1 99  ARG n 
1 100 SER n 
1 101 LYS n 
1 102 ALA n 
1 103 THR n 
1 104 ARG n 
1 105 ILE n 
1 106 ASN n 
1 107 VAL n 
1 108 SER n 
1 109 ARG n 
1 110 GLU n 
1 111 ALA n 
1 112 ASP n 
1 113 GLY n 
1 114 LEU n 
1 115 PRO n 
1 116 PRO n 
1 117 ILE n 
1 118 GLU n 
1 119 ALA n 
1 120 GLU n 
1 121 PRO n 
1 122 GLU n 
1 123 GLU n 
1 124 THR n 
1 125 ALA n 
1 126 PHE n 
1 127 GLY n 
1 128 PRO n 
1 129 ASP n 
1 130 GLY n 
1 131 LYS n 
1 132 LEU n 
1 133 LYS n 
1 134 GLU n 
1 135 ARG n 
1 136 PRO n 
1 137 GLY n 
1 138 ILE n 
1 139 ASN n 
1 140 PRO n 
1 141 SER n 
1 142 ILE n 
1 143 TYR n 
1 144 CYS n 
1 145 TYR n 
1 146 GLN n 
1 147 GLN n 
1 148 VAL n 
1 149 SER n 
1 150 PRO n 
1 151 VAL n 
1 152 PRO n 
1 153 TYR n 
1 154 ASN n 
1 155 PRO n 
1 156 ALA n 
1 157 LYS n 
1 158 HIS n 
1 159 PRO n 
1 160 ALA n 
1 161 LEU n 
1 162 PRO n 
1 163 PHE n 
1 164 SER n 
1 165 GLY n 
1 166 VAL n 
1 167 ASP n 
1 168 PRO n 
1 169 GLY n 
1 170 ALA n 
1 171 PRO n 
1 172 LEU n 
1 173 PRO n 
1 174 LEU n 
1 175 GLY n 
1 176 THR n 
1 177 PRO n 
1 178 ASN n 
1 179 ARG n 
1 180 LEU n 
1 181 SER n 
1 182 ILE n 
1 183 PRO n 
1 184 LYS n 
1 185 GLY n 
1 186 GLN n 
1 187 PRO n 
1 188 GLY n 
1 189 TYR n 
1 190 VAL n 
1 191 PRO n 
1 192 GLU n 
1 193 TRP n 
1 194 GLN n 
1 195 ARG n 
1 196 PRO n 
1 197 HIS n 
1 198 LEU n 
1 199 SER n 
1 200 THR n 
1 201 LYS n 
1 202 ASN n 
1 203 LYS n 
1 204 ARG n 
1 205 ILE n 
1 206 ARG n 
1 207 LYS n 
1 208 TRP n 
1 209 TYR n 
1 210 ALA n 
1 211 ARG n 
1 212 ALA n 
1 213 ASN n 
1 214 TRP n 
1 215 ARG n 
1 216 ARG n 
1 217 LYS n 
1 218 PRO n 
1 219 GLY n 
1 220 ARG n 
1 221 LYS n 
1 222 SER n 
1 223 VAL n 
1 224 LEU n 
1 225 ASP n 
1 226 GLU n 
1 227 ALA n 
1 228 LYS n 
1 229 LEU n 
1 230 LYS n 
1 231 GLU n 
1 232 ALA n 
1 233 ALA n 
1 234 LEU n 
1 235 LYS n 
1 236 GLU n 
1 237 ALA n 
1 238 ILE n 
1 239 PRO n 
1 240 ILE n 
1 241 ILE n 
1 242 VAL n 
1 243 THR n 
1 244 ILE n 
1 245 GLY n 
1 246 LYS n 
1 247 ASP n 
1 248 TRP n 
1 249 ILE n 
1 250 VAL n 
1 251 MET n 
1 252 ASP n 
1 253 ALA n 
1 254 ARG n 
1 255 GLY n 
1 256 LEU n 
1 257 LEU n 
1 258 ARG n 
1 259 ALA n 
1 260 VAL n 
1 261 TYR n 
1 262 TRP n 
1 263 ARG n 
1 264 GLY n 
1 265 ILE n 
1 266 ALA n 
1 267 LYS n 
1 268 PRO n 
1 269 GLY n 
1 270 LEU n 
1 271 SER n 
1 272 LEU n 
1 273 LYS n 
1 274 GLU n 
1 275 LEU n 
1 276 LEU n 
1 277 GLY n 
1 278 PHE n 
1 279 PHE n 
1 280 SER n 
1 281 GLY n 
1 282 ASP n 
1 283 PRO n 
1 284 VAL n 
1 285 LEU n 
1 286 ASP n 
1 287 PRO n 
1 288 LYS n 
1 289 ARG n 
1 290 GLY n 
1 291 ILE n 
1 292 ALA n 
1 293 THR n 
1 294 PHE n 
1 295 THR n 
1 296 PHE n 
1 297 LYS n 
1 298 LEU n 
1 299 GLY n 
1 300 ALA n 
2 1   DC  n 
2 2   DT  n 
2 3   DG  n 
2 4   DC  n 
2 5   DC  n 
2 6   DC  n 
2 7   DT  n 
2 8   DT  n 
2 9   DG  n 
2 10  DC  n 
2 11  DA  n 
2 12  DA  n 
2 13  DC  n 
2 14  DT  n 
2 15  DT  n 
2 16  DC  n 
2 17  DA  n 
2 18  DG  n 
2 19  DC  n 
2 20  DA  n 
2 21  DG  n 
2 22  DC  n 
2 23  DA  n 
2 24  DC  n 
2 25  DG  n 
2 26  DT  n 
2 27  DA  n 
2 28  DG  n 
2 29  DG  n 
2 30  DG  n 
2 31  DG  n 
2 32  DA  n 
2 33  DG  n 
2 34  DA  n 
2 35  DA  n 
2 36  DT  n 
2 37  DT  n 
2 38  DG  n 
2 39  DG  n 
2 40  DC  n 
2 41  DC  n 
2 42  DA  n 
3 1   U   n 
3 2   C   n 
3 3   A   n 
3 4   A   n 
3 5   C   n 
3 6   G   n 
3 7   C   n 
3 8   U   n 
3 9   U   n 
3 10  G   n 
3 11  C   n 
3 12  U   n 
3 13  C   n 
3 14  G   n 
3 15  G   n 
3 16  U   n 
3 17  U   n 
3 18  C   n 
3 19  G   n 
3 20  C   n 
3 21  C   n 
3 22  G   n 
3 23  A   n 
3 24  G   n 
3 25  A   n 
3 26  C   n 
3 27  U   n 
3 28  C   n 
3 29  C   n 
3 30  C   n 
3 31  C   n 
3 32  U   n 
3 33  A   n 
3 34  C   n 
3 35  G   n 
3 36  U   n 
3 37  G   n 
3 38  C   n 
3 39  U   n 
3 40  G   n 
3 41  C   n 
3 42  U   n 
3 43  G   n 
3 44  A   n 
3 45  A   n 
3 46  G   n 
4 1   DT  n 
4 2   DG  n 
4 3   DG  n 
4 4   DC  n 
4 5   DC  n 
4 6   DA  n 
4 7   DA  n 
4 8   DT  n 
4 9   DT  n 
4 10  DC  n 
4 11  DT  n 
4 12  DC  n 
4 13  DC  n 
4 14  DC  n 
4 15  DC  n 
4 16  DT  n 
4 17  DA  n 
4 18  DC  n 
4 19  DG  n 
4 20  DT  n 
4 21  DG  n 
4 22  DC  n 
4 23  DT  n 
4 24  DG  n 
4 25  DC  n 
4 26  DT  n 
4 27  DG  n 
4 28  DA  n 
4 29  DA  n 
4 30  DG  n 
4 31  DT  n 
4 32  DT  n 
4 33  DG  n 
4 34  DC  n 
4 35  DA  n 
4 36  DA  n 
4 37  DG  n 
4 38  DG  n 
4 39  DG  n 
4 40  DC  n 
4 41  DA  n 
4 42  DG  n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 300 ? ? ? ? ? ? ? ? ? 'unclassified sequences' 12908 ? ? ? ? ? ? ? ? 
'Escherichia coli BL21(DE3)' 469008 ? ? ? ? ? ? 'BL21(DE3)' ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 42  ? ? ? ? ? ? ? ? ? 'unclassified sequences' 12908 ? ? ? ? ? ? ? ? 'unclassified sequences' 
12908  ? ? ? ? ? ? ?           ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 46  ? ? ? ? ? ? ? ? ? 'unclassified sequences' 12908 ? ? ? ? ? ? ? ? 'unclassified sequences' 
12908  ? ? ? ? ? ? ?           ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 'Biological sequence' 1 42  ? ? ? ? ? ? ? ? ? 'unclassified sequences' 12908 ? ? ? ? ? ? ? ? 'unclassified sequences' 
12908  ? ? ? ? ? ? ?           ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A   'RNA linking'       y "ADENOSINE-5'-MONOPHOSPHATE"         ? 'C10 H14 N5 O7 P' 347.221 
ALA 'L-peptide linking' y ALANINE                              ? 'C3 H7 N O2'      89.093  
ARG 'L-peptide linking' y ARGININE                             ? 'C6 H15 N4 O2 1'  175.209 
ASN 'L-peptide linking' y ASPARAGINE                           ? 'C4 H8 N2 O3'     132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                      ? 'C4 H7 N O4'      133.103 
C   'RNA linking'       y "CYTIDINE-5'-MONOPHOSPHATE"          ? 'C9 H14 N3 O8 P'  323.197 
CYS 'L-peptide linking' y CYSTEINE                             ? 'C3 H7 N O2 S'    121.158 
DA  'DNA linking'       y "2'-DEOXYADENOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O6 P' 331.222 
DC  'DNA linking'       y "2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE"  ? 'C9 H14 N3 O7 P'  307.197 
DG  'DNA linking'       y "2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O7 P' 347.221 
DT  'DNA linking'       y "THYMIDINE-5'-MONOPHOSPHATE"         ? 'C10 H15 N2 O8 P' 322.208 
G   'RNA linking'       y "GUANOSINE-5'-MONOPHOSPHATE"         ? 'C10 H14 N5 O8 P' 363.221 
GLN 'L-peptide linking' y GLUTAMINE                            ? 'C5 H10 N2 O3'    146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                      ? 'C5 H9 N O4'      147.129 
GLY 'peptide linking'   y GLYCINE                              ? 'C2 H5 N O2'      75.067  
HIS 'L-peptide linking' y HISTIDINE                            ? 'C6 H10 N3 O2 1'  156.162 
ILE 'L-peptide linking' y ISOLEUCINE                           ? 'C6 H13 N O2'     131.173 
LEU 'L-peptide linking' y LEUCINE                              ? 'C6 H13 N O2'     131.173 
LYS 'L-peptide linking' y LYSINE                               ? 'C6 H15 N2 O2 1'  147.195 
MET 'L-peptide linking' y METHIONINE                           ? 'C5 H11 N O2 S'   149.211 
PHE 'L-peptide linking' y PHENYLALANINE                        ? 'C9 H11 N O2'     165.189 
PRO 'L-peptide linking' y PROLINE                              ? 'C5 H9 N O2'      115.130 
SER 'L-peptide linking' y SERINE                               ? 'C3 H7 N O3'      105.093 
THR 'L-peptide linking' y THREONINE                            ? 'C4 H9 N O3'      119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                           ? 'C11 H12 N2 O2'   204.225 
TYR 'L-peptide linking' y TYROSINE                             ? 'C9 H11 N O3'     181.189 
U   'RNA linking'       y "URIDINE-5'-MONOPHOSPHATE"           ? 'C9 H13 N2 O9 P'  324.181 
VAL 'L-peptide linking' y VALINE                               ? 'C5 H11 N O2'     117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   PHE 1   57  ?   ?   ?   A . n 
A 1 2   CYS 2   58  58  CYS CYS A . n 
A 1 3   PRO 3   59  59  PRO PRO A . n 
A 1 4   PRO 4   60  60  PRO PRO A . n 
A 1 5   ALA 5   61  61  ALA ALA A . n 
A 1 6   LYS 6   62  62  LYS LYS A . n 
A 1 7   VAL 7   63  63  VAL VAL A . n 
A 1 8   ASN 8   64  64  ASN ASN A . n 
A 1 9   ILE 9   65  65  ILE ILE A . n 
A 1 10  LEU 10  66  66  LEU LEU A . n 
A 1 11  ALA 11  67  67  ALA ALA A . n 
A 1 12  GLN 12  68  68  GLN GLN A . n 
A 1 13  SER 13  69  69  SER SER A . n 
A 1 14  ARG 14  70  70  ARG ARG A . n 
A 1 15  PRO 15  71  71  PRO PRO A . n 
A 1 16  LEU 16  72  72  LEU LEU A . n 
A 1 17  SER 17  73  73  SER SER A . n 
A 1 18  GLU 18  74  74  GLU GLU A . n 
A 1 19  TRP 19  75  75  TRP TRP A . n 
A 1 20  PRO 20  76  76  PRO PRO A . n 
A 1 21  ILE 21  77  77  ILE ILE A . n 
A 1 22  ASN 22  78  78  ASN ASN A . n 
A 1 23  LEU 23  79  79  LEU LEU A . n 
A 1 24  VAL 24  80  80  VAL VAL A . n 
A 1 25  SER 25  81  81  SER SER A . n 
A 1 26  LYS 26  82  82  LYS LYS A . n 
A 1 27  GLY 27  83  83  GLY GLY A . n 
A 1 28  VAL 28  84  84  VAL VAL A . n 
A 1 29  GLN 29  85  85  GLN GLN A . n 
A 1 30  GLU 30  86  86  GLU GLU A . n 
A 1 31  TYR 31  87  87  TYR TYR A . n 
A 1 32  VAL 32  88  88  VAL VAL A . n 
A 1 33  TYR 33  89  89  TYR TYR A . n 
A 1 34  GLY 34  90  90  GLY GLY A . n 
A 1 35  LEU 35  91  91  LEU LEU A . n 
A 1 36  THR 36  92  92  THR THR A . n 
A 1 37  ALA 37  93  93  ALA ALA A . n 
A 1 38  ALA 38  94  94  ALA ALA A . n 
A 1 39  GLU 39  95  95  GLU GLU A . n 
A 1 40  ARG 40  96  96  ARG ARG A . n 
A 1 41  GLU 41  97  97  GLU GLU A . n 
A 1 42  ALA 42  98  98  ALA ALA A . n 
A 1 43  ASN 43  99  99  ASN ASN A . n 
A 1 44  GLY 44  100 100 GLY GLY A . n 
A 1 45  ASP 45  101 ?   ?   ?   A . n 
A 1 46  PHE 46  102 ?   ?   ?   A . n 
A 1 47  GLY 47  103 ?   ?   ?   A . n 
A 1 48  THR 48  104 104 THR THR A . n 
A 1 49  SER 49  105 105 SER SER A . n 
A 1 50  ARG 50  106 106 ARG ARG A . n 
A 1 51  LYS 51  107 107 LYS LYS A . n 
A 1 52  SER 52  108 108 SER SER A . n 
A 1 53  LEU 53  109 109 LEU LEU A . n 
A 1 54  ASP 54  110 110 ASP ASP A . n 
A 1 55  ARG 55  111 111 ARG ARG A . n 
A 1 56  TRP 56  112 112 TRP TRP A . n 
A 1 57  PHE 57  113 113 PHE PHE A . n 
A 1 58  ALA 58  114 114 ALA ALA A . n 
A 1 59  ARG 59  115 115 ARG ARG A . n 
A 1 60  THR 60  116 116 THR THR A . n 
A 1 61  GLY 61  117 117 GLY GLY A . n 
A 1 62  VAL 62  118 118 VAL VAL A . n 
A 1 63  PRO 63  119 119 PRO PRO A . n 
A 1 64  THR 64  120 120 THR THR A . n 
A 1 65  HIS 65  121 121 HIS HIS A . n 
A 1 66  GLY 66  122 122 GLY GLY A . n 
A 1 67  TYR 67  123 123 TYR TYR A . n 
A 1 68  THR 68  124 124 THR THR A . n 
A 1 69  THR 69  125 125 THR THR A . n 
A 1 70  VAL 70  126 126 VAL VAL A . n 
A 1 71  GLN 71  127 127 GLN GLN A . n 
A 1 72  GLY 72  128 128 GLY GLY A . n 
A 1 73  LEU 73  129 129 LEU LEU A . n 
A 1 74  ASN 74  130 130 ASN ASN A . n 
A 1 75  LEU 75  131 131 LEU LEU A . n 
A 1 76  ILE 76  132 132 ILE ILE A . n 
A 1 77  LEU 77  133 133 LEU LEU A . n 
A 1 78  ARG 78  134 134 ARG ARG A . n 
A 1 79  HIS 79  135 135 HIS HIS A . n 
A 1 80  THR 80  136 136 THR THR A . n 
A 1 81  PHE 81  137 137 PHE PHE A . n 
A 1 82  ASN 82  138 138 ASN ASN A . n 
A 1 83  ARG 83  139 139 ARG ARG A . n 
A 1 84  TYR 84  140 140 TYR TYR A . n 
A 1 85  ASP 85  141 141 ASP ASP A . n 
A 1 86  GLY 86  142 142 GLY GLY A . n 
A 1 87  VAL 87  143 143 VAL VAL A . n 
A 1 88  ILE 88  144 144 ILE ILE A . n 
A 1 89  LYS 89  145 145 LYS LYS A . n 
A 1 90  LYS 90  146 146 LYS LYS A . n 
A 1 91  VAL 91  147 147 VAL VAL A . n 
A 1 92  GLU 92  148 148 GLU GLU A . n 
A 1 93  THR 93  149 149 THR THR A . n 
A 1 94  ARG 94  150 150 ARG ARG A . n 
A 1 95  ASN 95  151 151 ASN ASN A . n 
A 1 96  GLU 96  152 152 GLU GLU A . n 
A 1 97  LYS 97  153 153 LYS LYS A . n 
A 1 98  ARG 98  154 154 ARG ARG A . n 
A 1 99  ARG 99  155 155 ARG ARG A . n 
A 1 100 SER 100 156 156 SER SER A . n 
A 1 101 LYS 101 157 157 LYS LYS A . n 
A 1 102 ALA 102 158 158 ALA ALA A . n 
A 1 103 THR 103 159 159 THR THR A . n 
A 1 104 ARG 104 160 160 ARG ARG A . n 
A 1 105 ILE 105 161 161 ILE ILE A . n 
A 1 106 ASN 106 162 162 ASN ASN A . n 
A 1 107 VAL 107 163 163 VAL VAL A . n 
A 1 108 SER 108 164 164 SER SER A . n 
A 1 109 ARG 109 165 165 ARG ARG A . n 
A 1 110 GLU 110 166 166 GLU GLU A . n 
A 1 111 ALA 111 167 167 ALA ALA A . n 
A 1 112 ASP 112 168 168 ASP ASP A . n 
A 1 113 GLY 113 169 169 GLY GLY A . n 
A 1 114 LEU 114 170 170 LEU LEU A . n 
A 1 115 PRO 115 171 171 PRO PRO A . n 
A 1 116 PRO 116 172 172 PRO PRO A . n 
A 1 117 ILE 117 173 173 ILE ILE A . n 
A 1 118 GLU 118 174 174 GLU GLU A . n 
A 1 119 ALA 119 175 175 ALA ALA A . n 
A 1 120 GLU 120 176 176 GLU GLU A . n 
A 1 121 PRO 121 177 177 PRO PRO A . n 
A 1 122 GLU 122 178 178 GLU GLU A . n 
A 1 123 GLU 123 179 179 GLU ALA A . n 
A 1 124 THR 124 180 180 THR THR A . n 
A 1 125 ALA 125 181 181 ALA ALA A . n 
A 1 126 PHE 126 182 182 PHE PHE A . n 
A 1 127 GLY 127 183 183 GLY GLY A . n 
A 1 128 PRO 128 184 184 PRO PRO A . n 
A 1 129 ASP 129 185 185 ASP ASP A . n 
A 1 130 GLY 130 186 186 GLY GLY A . n 
A 1 131 LYS 131 187 187 LYS LYS A . n 
A 1 132 LEU 132 188 188 LEU LEU A . n 
A 1 133 LYS 133 189 189 LYS LYS A . n 
A 1 134 GLU 134 190 190 GLU GLU A . n 
A 1 135 ARG 135 191 191 ARG ARG A . n 
A 1 136 PRO 136 192 192 PRO PRO A . n 
A 1 137 GLY 137 193 193 GLY GLY A . n 
A 1 138 ILE 138 194 194 ILE ILE A . n 
A 1 139 ASN 139 195 195 ASN ASN A . n 
A 1 140 PRO 140 196 196 PRO PRO A . n 
A 1 141 SER 141 197 197 SER SER A . n 
A 1 142 ILE 142 198 198 ILE ILE A . n 
A 1 143 TYR 143 199 199 TYR TYR A . n 
A 1 144 CYS 144 200 200 CYS CYS A . n 
A 1 145 TYR 145 201 201 TYR TYR A . n 
A 1 146 GLN 146 202 202 GLN GLN A . n 
A 1 147 GLN 147 203 203 GLN GLN A . n 
A 1 148 VAL 148 204 204 VAL VAL A . n 
A 1 149 SER 149 205 205 SER SER A . n 
A 1 150 PRO 150 206 206 PRO PRO A . n 
A 1 151 VAL 151 207 207 VAL VAL A . n 
A 1 152 PRO 152 208 208 PRO PRO A . n 
A 1 153 TYR 153 209 209 TYR TYR A . n 
A 1 154 ASN 154 210 210 ASN ASN A . n 
A 1 155 PRO 155 211 211 PRO PRO A . n 
A 1 156 ALA 156 212 212 ALA ALA A . n 
A 1 157 LYS 157 213 213 LYS LYS A . n 
A 1 158 HIS 158 214 214 HIS HIS A . n 
A 1 159 PRO 159 215 215 PRO PRO A . n 
A 1 160 ALA 160 216 216 ALA ALA A . n 
A 1 161 LEU 161 217 217 LEU LEU A . n 
A 1 162 PRO 162 218 218 PRO PRO A . n 
A 1 163 PHE 163 219 219 PHE PHE A . n 
A 1 164 SER 164 220 220 SER SER A . n 
A 1 165 GLY 165 221 221 GLY GLY A . n 
A 1 166 VAL 166 222 222 VAL VAL A . n 
A 1 167 ASP 167 223 223 ASP ASP A . n 
A 1 168 PRO 168 224 224 PRO PRO A . n 
A 1 169 GLY 169 225 225 GLY GLY A . n 
A 1 170 ALA 170 226 226 ALA ALA A . n 
A 1 171 PRO 171 227 227 PRO PRO A . n 
A 1 172 LEU 172 228 228 LEU LEU A . n 
A 1 173 PRO 173 229 229 PRO PRO A . n 
A 1 174 LEU 174 230 230 LEU LEU A . n 
A 1 175 GLY 175 231 ?   ?   ?   A . n 
A 1 176 THR 176 232 ?   ?   ?   A . n 
A 1 177 PRO 177 233 ?   ?   ?   A . n 
A 1 178 ASN 178 234 ?   ?   ?   A . n 
A 1 179 ARG 179 235 ?   ?   ?   A . n 
A 1 180 LEU 180 236 ?   ?   ?   A . n 
A 1 181 SER 181 237 ?   ?   ?   A . n 
A 1 182 ILE 182 238 ?   ?   ?   A . n 
A 1 183 PRO 183 239 ?   ?   ?   A . n 
A 1 184 LYS 184 240 ?   ?   ?   A . n 
A 1 185 GLY 185 241 ?   ?   ?   A . n 
A 1 186 GLN 186 242 ?   ?   ?   A . n 
A 1 187 PRO 187 243 243 PRO PRO A . n 
A 1 188 GLY 188 244 244 GLY GLY A . n 
A 1 189 TYR 189 245 245 TYR TYR A . n 
A 1 190 VAL 190 246 246 VAL VAL A . n 
A 1 191 PRO 191 247 247 PRO PRO A . n 
A 1 192 GLU 192 248 248 GLU GLU A . n 
A 1 193 TRP 193 249 249 TRP TRP A . n 
A 1 194 GLN 194 250 250 GLN GLN A . n 
A 1 195 ARG 195 251 251 ARG ARG A . n 
A 1 196 PRO 196 252 252 PRO PRO A . n 
A 1 197 HIS 197 253 253 HIS HIS A . n 
A 1 198 LEU 198 254 254 LEU LEU A . n 
A 1 199 SER 199 255 255 SER SER A . n 
A 1 200 THR 200 256 256 THR THR A . n 
A 1 201 LYS 201 257 257 LYS LYS A . n 
A 1 202 ASN 202 258 258 ASN ASN A . n 
A 1 203 LYS 203 259 259 LYS LYS A . n 
A 1 204 ARG 204 260 260 ARG ARG A . n 
A 1 205 ILE 205 261 261 ILE ILE A . n 
A 1 206 ARG 206 262 262 ARG ARG A . n 
A 1 207 LYS 207 263 263 LYS LYS A . n 
A 1 208 TRP 208 264 264 TRP TRP A . n 
A 1 209 TYR 209 265 265 TYR TYR A . n 
A 1 210 ALA 210 266 266 ALA ALA A . n 
A 1 211 ARG 211 267 267 ARG ARG A . n 
A 1 212 ALA 212 268 268 ALA ALA A . n 
A 1 213 ASN 213 269 269 ASN ASN A . n 
A 1 214 TRP 214 270 270 TRP TRP A . n 
A 1 215 ARG 215 271 271 ARG ARG A . n 
A 1 216 ARG 216 272 272 ARG ARG A . n 
A 1 217 LYS 217 273 273 LYS LYS A . n 
A 1 218 PRO 218 274 274 PRO PRO A . n 
A 1 219 GLY 219 275 275 GLY GLY A . n 
A 1 220 ARG 220 276 276 ARG ARG A . n 
A 1 221 LYS 221 277 277 LYS LYS A . n 
A 1 222 SER 222 278 278 SER SER A . n 
A 1 223 VAL 223 279 279 VAL VAL A . n 
A 1 224 LEU 224 280 280 LEU LEU A . n 
A 1 225 ASP 225 281 281 ASP ASP A . n 
A 1 226 GLU 226 282 282 GLU GLU A . n 
A 1 227 ALA 227 283 283 ALA ALA A . n 
A 1 228 LYS 228 284 284 LYS LYS A . n 
A 1 229 LEU 229 285 285 LEU LEU A . n 
A 1 230 LYS 230 286 286 LYS LYS A . n 
A 1 231 GLU 231 287 287 GLU GLU A . n 
A 1 232 ALA 232 288 288 ALA ALA A . n 
A 1 233 ALA 233 289 289 ALA ALA A . n 
A 1 234 LEU 234 290 290 LEU LEU A . n 
A 1 235 LYS 235 291 291 LYS LYS A . n 
A 1 236 GLU 236 292 292 GLU GLU A . n 
A 1 237 ALA 237 293 293 ALA ALA A . n 
A 1 238 ILE 238 294 294 ILE ILE A . n 
A 1 239 PRO 239 295 295 PRO PRO A . n 
A 1 240 ILE 240 296 296 ILE ILE A . n 
A 1 241 ILE 241 297 297 ILE ILE A . n 
A 1 242 VAL 242 298 298 VAL VAL A . n 
A 1 243 THR 243 299 299 THR THR A . n 
A 1 244 ILE 244 300 300 ILE ILE A . n 
A 1 245 GLY 245 301 301 GLY GLY A . n 
A 1 246 LYS 246 302 302 LYS LYS A . n 
A 1 247 ASP 247 303 303 ASP ASP A . n 
A 1 248 TRP 248 304 304 TRP TRP A . n 
A 1 249 ILE 249 305 305 ILE ILE A . n 
A 1 250 VAL 250 306 306 VAL VAL A . n 
A 1 251 MET 251 307 307 MET MET A . n 
A 1 252 ASP 252 308 308 ASP ASP A . n 
A 1 253 ALA 253 309 309 ALA ALA A . n 
A 1 254 ARG 254 310 310 ARG ARG A . n 
A 1 255 GLY 255 311 311 GLY GLY A . n 
A 1 256 LEU 256 312 312 LEU LEU A . n 
A 1 257 LEU 257 313 313 LEU LEU A . n 
A 1 258 ARG 258 314 314 ARG ARG A . n 
A 1 259 ALA 259 315 315 ALA ALA A . n 
A 1 260 VAL 260 316 316 VAL VAL A . n 
A 1 261 TYR 261 317 317 TYR TYR A . n 
A 1 262 TRP 262 318 318 TRP TRP A . n 
A 1 263 ARG 263 319 319 ARG ARG A . n 
A 1 264 GLY 264 320 320 GLY GLY A . n 
A 1 265 ILE 265 321 321 ILE ILE A . n 
A 1 266 ALA 266 322 322 ALA ALA A . n 
A 1 267 LYS 267 323 323 LYS LYS A . n 
A 1 268 PRO 268 324 324 PRO GLY A . n 
A 1 269 GLY 269 325 325 GLY ALA A . n 
A 1 270 LEU 270 326 326 LEU LEU A . n 
A 1 271 SER 271 327 327 SER SER A . n 
A 1 272 LEU 272 328 328 LEU LEU A . n 
A 1 273 LYS 273 329 329 LYS LYS A . n 
A 1 274 GLU 274 330 330 GLU GLU A . n 
A 1 275 LEU 275 331 331 LEU LEU A . n 
A 1 276 LEU 276 332 332 LEU LEU A . n 
A 1 277 GLY 277 333 333 GLY GLY A . n 
A 1 278 PHE 278 334 334 PHE PHE A . n 
A 1 279 PHE 279 335 ?   ?   ?   A . n 
A 1 280 SER 280 336 336 SER SER A . n 
A 1 281 GLY 281 337 337 GLY GLY A . n 
A 1 282 ASP 282 338 338 ASP ASP A . n 
A 1 283 PRO 283 339 339 PRO PRO A . n 
A 1 284 VAL 284 340 340 VAL VAL A . n 
A 1 285 LEU 285 341 341 LEU LEU A . n 
A 1 286 ASP 286 342 342 ASP ASP A . n 
A 1 287 PRO 287 343 343 PRO PRO A . n 
A 1 288 LYS 288 344 344 LYS LYS A . n 
A 1 289 ARG 289 345 345 ARG ARG A . n 
A 1 290 GLY 290 346 346 GLY GLY A . n 
A 1 291 ILE 291 347 347 ILE ILE A . n 
A 1 292 ALA 292 348 348 ALA ALA A . n 
A 1 293 THR 293 349 349 THR THR A . n 
A 1 294 PHE 294 350 350 PHE PHE A . n 
A 1 295 THR 295 351 351 THR THR A . n 
A 1 296 PHE 296 352 352 PHE PHE A . n 
A 1 297 LYS 297 353 353 LYS LYS A . n 
A 1 298 LEU 298 354 354 LEU LEU A . n 
A 1 299 GLY 299 355 355 GLY GLY A . n 
A 1 300 ALA 300 356 ?   ?   ?   A . n 
B 2 1   DC  1   -32 ?   ?   ?   C . n 
B 2 2   DT  2   -31 ?   ?   ?   C . n 
B 2 3   DG  3   -30 ?   ?   ?   C . n 
B 2 4   DC  4   -29 ?   ?   ?   C . n 
B 2 5   DC  5   -28 ?   ?   ?   C . n 
B 2 6   DC  6   -27 ?   ?   ?   C . n 
B 2 7   DT  7   -26 ?   ?   ?   C . n 
B 2 8   DT  8   -25 ?   ?   ?   C . n 
B 2 9   DG  9   -24 ?   ?   ?   C . n 
B 2 10  DC  10  -23 ?   ?   ?   C . n 
B 2 11  DA  11  -22 ?   ?   ?   C . n 
B 2 12  DA  12  -21 ?   ?   ?   C . n 
B 2 13  DC  13  -20 -20 DC  DC  C . n 
B 2 14  DT  14  -19 -19 DT  DT  C . n 
B 2 15  DT  15  -18 -18 DT  DT  C . n 
B 2 16  DC  16  -17 -17 DC  DC  C . n 
B 2 17  DA  17  -16 -16 DA  DA  C . n 
B 2 18  DG  18  -15 -15 DG  DG  C . n 
B 2 19  DC  19  -14 -14 DC  DC  C . n 
B 2 20  DA  20  -13 -13 DA  DA  C . n 
B 2 21  DG  21  -12 -12 DG  DG  C . n 
B 2 22  DC  22  -11 -11 DC  DC  C . n 
B 2 23  DA  23  -10 -10 DA  DA  C . n 
B 2 24  DC  24  -9  -9  DC  DC  C . n 
B 2 25  DG  25  -8  -8  DG  DG  C . n 
B 2 26  DT  26  -7  -7  DT  DT  C . n 
B 2 27  DA  27  -6  -6  DA  DA  C . n 
B 2 28  DG  28  -5  -5  DG  DG  C . n 
B 2 29  DG  29  -4  -4  DG  DG  C . n 
B 2 30  DG  30  -3  -3  DG  DG  C . n 
B 2 31  DG  31  -2  -2  DG  DG  C . n 
B 2 32  DA  32  -1  -1  DA  DA  C . n 
B 2 33  DG  33  0   0   DG  DG  C . n 
B 2 34  DA  34  1   1   DA  DA  C . n 
B 2 35  DA  35  2   2   DA  DA  C . n 
B 2 36  DT  36  3   3   DT  DT  C . n 
B 2 37  DT  37  4   4   DT  DT  C . n 
B 2 38  DG  38  5   5   DG  DG  C . n 
B 2 39  DG  39  6   6   DG  DG  C . n 
B 2 40  DC  40  7   ?   ?   ?   C . n 
B 2 41  DC  41  8   ?   ?   ?   C . n 
B 2 42  DA  42  9   ?   ?   ?   C . n 
C 3 1   U   1   -25 ?   ?   ?   B . n 
C 3 2   C   2   -24 ?   ?   ?   B . n 
C 3 3   A   3   -23 ?   ?   ?   B . n 
C 3 4   A   4   -22 ?   ?   ?   B . n 
C 3 5   C   5   -21 ?   ?   ?   B . n 
C 3 6   G   6   -20 ?   ?   ?   B . n 
C 3 7   C   7   -19 -19 C   C   B . n 
C 3 8   U   8   -18 -18 U   U   B . n 
C 3 9   U   9   -17 -17 U   U   B . n 
C 3 10  G   10  -16 -16 G   G   B . n 
C 3 11  C   11  -15 -15 C   C   B . n 
C 3 12  U   12  -14 -14 U   U   B . n 
C 3 13  C   13  -13 -13 C   C   B . n 
C 3 14  G   14  -12 -12 G   G   B . n 
C 3 15  G   15  -11 -11 G   G   B . n 
C 3 16  U   16  -10 -10 U   U   B . n 
C 3 17  U   17  -9  -9  U   U   B . n 
C 3 18  C   18  -8  -8  C   C   B . n 
C 3 19  G   19  -7  -7  G   G   B . n 
C 3 20  C   20  -6  -6  C   C   B . n 
C 3 21  C   21  -5  -5  C   C   B . n 
C 3 22  G   22  -4  -4  G   G   B . n 
C 3 23  A   23  -3  -3  A   A   B . n 
C 3 24  G   24  -2  -2  G   G   B . n 
C 3 25  A   25  -1  -1  A   A   B . n 
C 3 26  C   26  0   0   C   C   B . n 
C 3 27  U   27  1   1   U   U   B . n 
C 3 28  C   28  2   2   C   C   B . n 
C 3 29  C   29  3   3   C   C   B . n 
C 3 30  C   30  4   4   C   C   B . n 
C 3 31  C   31  5   5   C   C   B . n 
C 3 32  U   32  6   6   U   U   B . n 
C 3 33  A   33  7   7   A   A   B . n 
C 3 34  C   34  8   8   C   C   B . n 
C 3 35  G   35  9   9   G   G   B . n 
C 3 36  U   36  10  10  U   U   B . n 
C 3 37  G   37  11  11  G   G   B . n 
C 3 38  C   38  12  12  C   C   B . n 
C 3 39  U   39  13  13  U   U   B . n 
C 3 40  G   40  14  14  G   G   B . n 
C 3 41  C   41  15  15  C   C   B . n 
C 3 42  U   42  16  16  U   U   B . n 
C 3 43  G   43  17  17  G   G   B . n 
C 3 44  A   44  18  18  A   A   B . n 
C 3 45  A   45  19  19  A   A   B . n 
C 3 46  G   46  20  20  G   G   B . n 
D 4 1   DT  1   -9  ?   ?   ?   D . n 
D 4 2   DG  2   -8  ?   ?   ?   D . n 
D 4 3   DG  3   -7  ?   ?   ?   D . n 
D 4 4   DC  4   -6  -6  DC  DC  D . n 
D 4 5   DC  5   -5  -5  DC  DC  D . n 
D 4 6   DA  6   -4  -4  DA  DA  D . n 
D 4 7   DA  7   -3  -3  DA  DA  D . n 
D 4 8   DT  8   -2  -2  DT  DT  D . n 
D 4 9   DT  9   -1  -1  DT  DT  D . n 
D 4 10  DC  10  0   0   DC  DC  D . n 
D 4 11  DT  11  1   ?   ?   ?   D . n 
D 4 12  DC  12  2   ?   ?   ?   D . n 
D 4 13  DC  13  3   ?   ?   ?   D . n 
D 4 14  DC  14  4   ?   ?   ?   D . n 
D 4 15  DC  15  5   ?   ?   ?   D . n 
D 4 16  DT  16  6   ?   ?   ?   D . n 
D 4 17  DA  17  7   ?   ?   ?   D . n 
D 4 18  DC  18  8   ?   ?   ?   D . n 
D 4 19  DG  19  9   ?   ?   ?   D . n 
D 4 20  DT  20  10  ?   ?   ?   D . n 
D 4 21  DG  21  11  ?   ?   ?   D . n 
D 4 22  DC  22  12  ?   ?   ?   D . n 
D 4 23  DT  23  13  ?   ?   ?   D . n 
D 4 24  DG  24  14  ?   ?   ?   D . n 
D 4 25  DC  25  15  ?   ?   ?   D . n 
D 4 26  DT  26  16  ?   ?   ?   D . n 
D 4 27  DG  27  17  ?   ?   ?   D . n 
D 4 28  DA  28  18  ?   ?   ?   D . n 
D 4 29  DA  29  19  ?   ?   ?   D . n 
D 4 30  DG  30  20  ?   ?   ?   D . n 
D 4 31  DT  31  21  ?   ?   ?   D . n 
D 4 32  DT  32  22  ?   ?   ?   D . n 
D 4 33  DG  33  23  ?   ?   ?   D . n 
D 4 34  DC  34  24  ?   ?   ?   D . n 
D 4 35  DA  35  25  ?   ?   ?   D . n 
D 4 36  DA  36  26  ?   ?   ?   D . n 
D 4 37  DG  37  27  ?   ?   ?   D . n 
D 4 38  DG  38  28  ?   ?   ?   D . n 
D 4 39  DG  39  29  ?   ?   ?   D . n 
D 4 40  DC  40  30  ?   ?   ?   D . n 
D 4 41  DA  41  31  ?   ?   ?   D . n 
D 4 42  DG  42  32  ?   ?   ?   D . n 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 Y 1 A GLU 179 ? CG  ? A GLU 123 CG  
2 1 Y 1 A GLU 179 ? CD  ? A GLU 123 CD  
3 1 Y 1 A GLU 179 ? OE1 ? A GLU 123 OE1 
4 1 Y 1 A GLU 179 ? OE2 ? A GLU 123 OE2 
5 1 Y 1 A PRO 324 ? CB  ? A PRO 268 CB  
6 1 Y 1 A PRO 324 ? CG  ? A PRO 268 CG  
7 1 Y 1 A PRO 324 ? CD  ? A PRO 268 CD  
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8WS5 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     8WS5 
_struct.title                        'Cryo-EM structure of Cas12-1-N2/crRNA/Target DNA complex' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8WS5 
_struct_keywords.text            'Crispr-Cas, RNA BINDING PROTEIN-RNA-DNA complex' 
_struct_keywords.pdbx_keywords   'RNA BINDING PROTEIN/RNA/DNA' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 8WS5 8WS5 ? 1 ? 1 
2 PDB 8WS5 8WS5 ? 2 ? 1 
3 PDB 8WS5 8WS5 ? 3 ? 1 
4 PDB 8WS5 8WS5 ? 4 ? 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8WS5 A 1 ? 300 ? 8WS5 57  ? 356 ? 57  356 
2 2 8WS5 C 1 ? 42  ? 8WS5 -32 ? 9   ? -32 9   
3 3 8WS5 B 1 ? 46  ? 8WS5 -25 ? 20  ? -25 20  
4 4 8WS5 D 1 ? 42  ? 8WS5 -9  ? 32  ? -9  32  
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 AA1 PRO A 15  ? GLU A 18  ? PRO A 71  GLU A 74  5 ? 4  
HELX_P HELX_P2 AA2 TRP A 19  ? TYR A 33  ? TRP A 75  TYR A 89  1 ? 15 
HELX_P HELX_P3 AA3 ALA A 38  ? GLY A 44  ? ALA A 94  GLY A 100 1 ? 7  
HELX_P HELX_P4 AA4 LYS A 51  ? THR A 60  ? LYS A 107 THR A 116 1 ? 10 
HELX_P HELX_P5 AA5 THR A 69  ? GLY A 113 ? THR A 125 GLY A 169 1 ? 45 
HELX_P HELX_P6 AA6 PRO A 191 ? ARG A 195 ? PRO A 247 ARG A 251 5 ? 5  
HELX_P HELX_P7 AA7 ALA A 210 ? TRP A 214 ? ALA A 266 TRP A 270 5 ? 5  
HELX_P HELX_P8 AA8 ALA A 227 ? GLU A 236 ? ALA A 283 GLU A 292 1 ? 10 
HELX_P HELX_P9 AA9 ALA A 253 ? ARG A 263 ? ALA A 309 ARG A 319 1 ? 11 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
hydrog1  hydrog ? ? C G  10 N1 ? ? ? 1_555 C A  25 N1 ? ? B G  -16 B A  -1 1_555 ? ? ? ? ? ? TYPE_8_PAIR    ? ? ? 
hydrog2  hydrog ? ? C G  10 O6 ? ? ? 1_555 C A  25 N6 ? ? B G  -16 B A  -1 1_555 ? ? ? ? ? ? TYPE_8_PAIR    ? ? ? 
hydrog3  hydrog ? ? C C  11 N3 ? ? ? 1_555 C G  24 N1 ? ? B C  -15 B G  -2 1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog4  hydrog ? ? C C  11 N4 ? ? ? 1_555 C G  24 O6 ? ? B C  -15 B G  -2 1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog5  hydrog ? ? C C  11 O2 ? ? ? 1_555 C G  24 N2 ? ? B C  -15 B G  -2 1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog6  hydrog ? ? C U  12 N3 ? ? ? 1_555 C A  23 N1 ? ? B U  -14 B A  -3 1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog7  hydrog ? ? C U  12 O4 ? ? ? 1_555 C A  23 N6 ? ? B U  -14 B A  -3 1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog8  hydrog ? ? C C  13 N3 ? ? ? 1_555 C G  22 N1 ? ? B C  -13 B G  -4 1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog9  hydrog ? ? C C  13 N4 ? ? ? 1_555 C G  22 O6 ? ? B C  -13 B G  -4 1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog10 hydrog ? ? C C  13 O2 ? ? ? 1_555 C G  22 N2 ? ? B C  -13 B G  -4 1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog11 hydrog ? ? C G  14 N1 ? ? ? 1_555 C C  21 N3 ? ? B G  -12 B C  -5 1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog12 hydrog ? ? C G  14 N2 ? ? ? 1_555 C C  21 O2 ? ? B G  -12 B C  -5 1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog13 hydrog ? ? C G  14 O6 ? ? ? 1_555 C C  21 N4 ? ? B G  -12 B C  -5 1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog14 hydrog ? ? C G  15 N1 ? ? ? 1_555 C C  20 N3 ? ? B G  -11 B C  -6 1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog15 hydrog ? ? C G  15 N2 ? ? ? 1_555 C C  20 O2 ? ? B G  -11 B C  -6 1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog16 hydrog ? ? C G  15 O6 ? ? ? 1_555 C C  20 N4 ? ? B G  -11 B C  -6 1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog17 hydrog ? ? C U  16 O2 ? ? ? 1_555 C G  19 N1 ? ? B U  -10 B G  -7 1_555 ? ? ? ? ? ? 'U-G MISPAIR'  ? ? ? 
hydrog18 hydrog ? ? B DT 14 N3 ? ? ? 1_555 C A  44 N7 ? ? C DT -19 B A  18 1_555 ? ? ? ? ? ? HOOGSTEEN      ? ? ? 
hydrog19 hydrog ? ? B DT 14 O4 ? ? ? 1_555 C A  44 N6 ? ? C DT -19 B A  18 1_555 ? ? ? ? ? ? HOOGSTEEN      ? ? ? 
hydrog20 hydrog ? ? B DC 16 N3 ? ? ? 1_555 C G  43 N1 ? ? C DC -17 B G  17 1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog21 hydrog ? ? B DC 16 N4 ? ? ? 1_555 C G  43 O6 ? ? C DC -17 B G  17 1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog22 hydrog ? ? B DC 16 O2 ? ? ? 1_555 C G  43 N2 ? ? C DC -17 B G  17 1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog23 hydrog ? ? B DA 17 N6 ? ? ? 1_555 C C  41 N3 ? ? C DA -16 B C  15 1_555 ? ? ? ? ? ? 'DA-C MISPAIR' ? ? ? 
hydrog24 hydrog ? ? B DG 18 N2 ? ? ? 1_555 C C  41 O2 ? ? C DG -15 B C  15 1_555 ? ? ? ? ? ? 'DG-C PAIR'    ? ? ? 
hydrog25 hydrog ? ? B DC 19 O2 ? ? ? 1_555 C G  40 N2 ? ? C DC -14 B G  14 1_555 ? ? ? ? ? ? 'DC-G PAIR'    ? ? ? 
hydrog26 hydrog ? ? B DA 20 N1 ? ? ? 1_555 C U  39 N3 ? ? C DA -13 B U  13 1_555 ? ? ? ? ? ? 'DA-U PAIR'    ? ? ? 
hydrog27 hydrog ? ? B DG 21 N1 ? ? ? 1_555 C C  38 N3 ? ? C DG -12 B C  12 1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog28 hydrog ? ? B DG 21 N2 ? ? ? 1_555 C C  38 O2 ? ? C DG -12 B C  12 1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog29 hydrog ? ? B DG 21 O6 ? ? ? 1_555 C C  38 N4 ? ? C DG -12 B C  12 1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog30 hydrog ? ? B DC 22 N4 ? ? ? 1_555 C G  37 O6 ? ? C DC -11 B G  11 1_555 ? ? ? ? ? ? 'DC-G PAIR'    ? ? ? 
hydrog31 hydrog ? ? B DA 23 N6 ? ? ? 1_555 C G  35 O6 ? ? C DA -10 B G  9  1_555 ? ? ? ? ? ? 'DA-G MISPAIR' ? ? ? 
hydrog32 hydrog ? ? B DA 23 N6 ? ? ? 1_555 C U  36 O4 ? ? C DA -10 B U  10 1_555 ? ? ? ? ? ? 'DA-U PAIR'    ? ? ? 
hydrog33 hydrog ? ? B DC 24 N4 ? ? ? 1_555 C G  35 O6 ? ? C DC -9  B G  9  1_555 ? ? ? ? ? ? 'DC-G PAIR'    ? ? ? 
hydrog34 hydrog ? ? B DT 26 N3 ? ? ? 1_555 C A  33 N1 ? ? C DT -7  B A  7  1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog35 hydrog ? ? B DT 26 O4 ? ? ? 1_555 C A  33 N6 ? ? C DT -7  B A  7  1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog36 hydrog ? ? B DA 27 N1 ? ? ? 1_555 C U  32 N3 ? ? C DA -6  B U  6  1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog37 hydrog ? ? B DA 27 N6 ? ? ? 1_555 C U  32 O4 ? ? C DA -6  B U  6  1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog38 hydrog ? ? B DG 28 N1 ? ? ? 1_555 C C  31 N3 ? ? C DG -5  B C  5  1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog39 hydrog ? ? B DG 28 N2 ? ? ? 1_555 C C  31 O2 ? ? C DG -5  B C  5  1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog40 hydrog ? ? B DG 28 O6 ? ? ? 1_555 C C  31 N4 ? ? C DG -5  B C  5  1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog41 hydrog ? ? B DG 29 N1 ? ? ? 1_555 C C  30 N3 ? ? C DG -4  B C  4  1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog42 hydrog ? ? B DG 29 N2 ? ? ? 1_555 C C  30 O2 ? ? C DG -4  B C  4  1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog43 hydrog ? ? B DG 29 O6 ? ? ? 1_555 C C  30 N4 ? ? C DG -4  B C  4  1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog44 hydrog ? ? B DG 30 N1 ? ? ? 1_555 C C  29 N3 ? ? C DG -3  B C  3  1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog45 hydrog ? ? B DG 30 N2 ? ? ? 1_555 C C  29 O2 ? ? C DG -3  B C  3  1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog46 hydrog ? ? B DG 30 O6 ? ? ? 1_555 C C  29 N4 ? ? C DG -3  B C  3  1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog47 hydrog ? ? B DG 31 N1 ? ? ? 1_555 C C  28 N3 ? ? C DG -2  B C  2  1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog48 hydrog ? ? B DG 31 N2 ? ? ? 1_555 C C  28 O2 ? ? C DG -2  B C  2  1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog49 hydrog ? ? B DG 31 O6 ? ? ? 1_555 C C  28 N4 ? ? C DG -2  B C  2  1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog50 hydrog ? ? B DA 32 N1 ? ? ? 1_555 C U  27 N3 ? ? C DA -1  B U  1  1_555 ? ? ? ? ? ? 'DA-U PAIR'    ? ? ? 
hydrog51 hydrog ? ? B DG 33 N1 ? ? ? 1_555 D DC 10 N3 ? ? C DG 0   D DC 0  1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog52 hydrog ? ? B DG 33 N2 ? ? ? 1_555 D DC 10 O2 ? ? C DG 0   D DC 0  1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog53 hydrog ? ? B DG 33 O6 ? ? ? 1_555 D DC 10 N4 ? ? C DG 0   D DC 0  1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog54 hydrog ? ? B DA 35 N1 ? ? ? 1_555 D DT 8  N3 ? ? C DA 2   D DT -2 1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog55 hydrog ? ? B DA 35 N6 ? ? ? 1_555 D DT 8  O4 ? ? C DA 2   D DT -2 1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog56 hydrog ? ? B DT 36 N3 ? ? ? 1_555 D DA 7  N1 ? ? C DT 3   D DA -3 1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog57 hydrog ? ? B DT 36 O4 ? ? ? 1_555 D DA 7  N6 ? ? C DT 3   D DA -3 1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog58 hydrog ? ? B DT 37 N3 ? ? ? 1_555 D DA 6  N1 ? ? C DT 4   D DA -4 1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog59 hydrog ? ? B DT 37 O4 ? ? ? 1_555 D DA 6  N6 ? ? C DT 4   D DA -4 1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog60 hydrog ? ? B DG 38 N1 ? ? ? 1_555 D DC 5  N3 ? ? C DG 5   D DC -5 1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog61 hydrog ? ? B DG 38 N2 ? ? ? 1_555 D DC 5  O2 ? ? C DG 5   D DC -5 1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog62 hydrog ? ? B DG 38 O6 ? ? ? 1_555 D DC 5  N4 ? ? C DG 5   D DC -5 1_555 ? ? ? ? ? ? WATSON-CRICK   ? ? ? 
hydrog63 hydrog ? ? B DG 39 N2 ? ? ? 1_555 D DC 4  O2 ? ? C DG 6   D DC -6 1_555 ? ? ? ? ? ? 'DG-DC PAIR'   ? ? ? 
hydrog64 hydrog ? ? B DG 39 N2 ? ? ? 1_555 D DC 5  O2 ? ? C DG 6   D DC -5 1_555 ? ? ? ? ? ? 'DG-DC PAIR'   ? ? ? 
# 
_struct_conn_type.id          hydrog 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 3 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ALA A 5   ? ASN A 8   ? ALA A 61  ASN A 64  
AA1 2 ILE A 291 ? PHE A 294 ? ILE A 347 PHE A 350 
AA1 3 VAL A 284 ? ASP A 286 ? VAL A 340 ASP A 342 
AA1 4 ILE A 142 ? TYR A 143 ? ILE A 198 TYR A 199 
AA2 1 ALA A 11  ? GLN A 12  ? ALA A 67  GLN A 68  
AA2 2 ASP A 247 ? VAL A 250 ? ASP A 303 VAL A 306 
AA2 3 ILE A 241 ? ILE A 244 ? ILE A 297 ILE A 300 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N VAL A 7   ? N VAL A 63  O ALA A 292 ? O ALA A 348 
AA1 2 3 O THR A 293 ? O THR A 349 N VAL A 284 ? N VAL A 340 
AA1 3 4 O LEU A 285 ? O LEU A 341 N ILE A 142 ? N ILE A 198 
AA2 1 2 N ALA A 11  ? N ALA A 67  O VAL A 250 ? O VAL A 306 
AA2 2 3 O ILE A 249 ? O ILE A 305 N VAL A 242 ? N VAL A 298 
# 
_pdbx_entry_details.entry_id                   8WS5 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 LEU A 109 ? ? -88.17  46.19   
2 1 PRO A 208 ? ? -63.24  -179.07 
3 1 ALA A 226 ? ? -172.26 133.60  
4 1 VAL A 246 ? ? 43.99   75.58   
5 1 HIS A 253 ? ? -145.17 31.03   
6 1 LYS A 259 ? ? -161.33 -169.37 
7 1 LEU A 328 ? ? -79.79  45.77   
8 1 LYS A 329 ? ? -131.94 -38.21  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8WS5 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8WS5 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.29 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               113093 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'The ternary complex of Cas12-1-N2 with crRNA and Target DNA' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3, 4' 
# 
_em_imaging.entry_id                        8WS5 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1200 
_em_imaging.nominal_defocus_max             5000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8WS5 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8WS5 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A PHE 57  ? A PHE 1   
2  1 Y 1 A ASP 101 ? A ASP 45  
3  1 Y 1 A PHE 102 ? A PHE 46  
4  1 Y 1 A GLY 103 ? A GLY 47  
5  1 Y 1 A GLY 231 ? A GLY 175 
6  1 Y 1 A THR 232 ? A THR 176 
7  1 Y 1 A PRO 233 ? A PRO 177 
8  1 Y 1 A ASN 234 ? A ASN 178 
9  1 Y 1 A ARG 235 ? A ARG 179 
10 1 Y 1 A LEU 236 ? A LEU 180 
11 1 Y 1 A SER 237 ? A SER 181 
12 1 Y 1 A ILE 238 ? A ILE 182 
13 1 Y 1 A PRO 239 ? A PRO 183 
14 1 Y 1 A LYS 240 ? A LYS 184 
15 1 Y 1 A GLY 241 ? A GLY 185 
16 1 Y 1 A GLN 242 ? A GLN 186 
17 1 Y 1 A PHE 335 ? A PHE 279 
18 1 Y 1 A ALA 356 ? A ALA 300 
19 1 Y 1 C DC  -32 ? B DC  1   
20 1 Y 1 C DT  -31 ? B DT  2   
21 1 Y 1 C DG  -30 ? B DG  3   
22 1 Y 1 C DC  -29 ? B DC  4   
23 1 Y 1 C DC  -28 ? B DC  5   
24 1 Y 1 C DC  -27 ? B DC  6   
25 1 Y 1 C DT  -26 ? B DT  7   
26 1 Y 1 C DT  -25 ? B DT  8   
27 1 Y 1 C DG  -24 ? B DG  9   
28 1 Y 1 C DC  -23 ? B DC  10  
29 1 Y 1 C DA  -22 ? B DA  11  
30 1 Y 1 C DA  -21 ? B DA  12  
31 1 Y 1 C DC  7   ? B DC  40  
32 1 Y 1 C DC  8   ? B DC  41  
33 1 Y 1 C DA  9   ? B DA  42  
34 1 Y 1 B U   -25 ? C U   1   
35 1 Y 1 B C   -24 ? C C   2   
36 1 Y 1 B A   -23 ? C A   3   
37 1 Y 1 B A   -22 ? C A   4   
38 1 Y 1 B C   -21 ? C C   5   
39 1 Y 1 B G   -20 ? C G   6   
40 1 Y 1 D DT  -9  ? D DT  1   
41 1 Y 1 D DG  -8  ? D DG  2   
42 1 Y 1 D DG  -7  ? D DG  3   
43 1 Y 1 D DT  1   ? D DT  11  
44 1 Y 1 D DC  2   ? D DC  12  
45 1 Y 1 D DC  3   ? D DC  13  
46 1 Y 1 D DC  4   ? D DC  14  
47 1 Y 1 D DC  5   ? D DC  15  
48 1 Y 1 D DT  6   ? D DT  16  
49 1 Y 1 D DA  7   ? D DA  17  
50 1 Y 1 D DC  8   ? D DC  18  
51 1 Y 1 D DG  9   ? D DG  19  
52 1 Y 1 D DT  10  ? D DT  20  
53 1 Y 1 D DG  11  ? D DG  21  
54 1 Y 1 D DC  12  ? D DC  22  
55 1 Y 1 D DT  13  ? D DT  23  
56 1 Y 1 D DG  14  ? D DG  24  
57 1 Y 1 D DC  15  ? D DC  25  
58 1 Y 1 D DT  16  ? D DT  26  
59 1 Y 1 D DG  17  ? D DG  27  
60 1 Y 1 D DA  18  ? D DA  28  
61 1 Y 1 D DA  19  ? D DA  29  
62 1 Y 1 D DG  20  ? D DG  30  
63 1 Y 1 D DT  21  ? D DT  31  
64 1 Y 1 D DT  22  ? D DT  32  
65 1 Y 1 D DG  23  ? D DG  33  
66 1 Y 1 D DC  24  ? D DC  34  
67 1 Y 1 D DA  25  ? D DA  35  
68 1 Y 1 D DA  26  ? D DA  36  
69 1 Y 1 D DG  27  ? D DG  37  
70 1 Y 1 D DG  28  ? D DG  38  
71 1 Y 1 D DG  29  ? D DG  39  
72 1 Y 1 D DC  30  ? D DC  40  
73 1 Y 1 D DA  31  ? D DA  41  
74 1 Y 1 D DG  32  ? D DG  42  
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A   OP3    O N N 1   
A   P      P N N 2   
A   OP1    O N N 3   
A   OP2    O N N 4   
A   "O5'"  O N N 5   
A   "C5'"  C N N 6   
A   "C4'"  C N R 7   
A   "O4'"  O N N 8   
A   "C3'"  C N S 9   
A   "O3'"  O N N 10  
A   "C2'"  C N R 11  
A   "O2'"  O N N 12  
A   "C1'"  C N R 13  
A   N9     N Y N 14  
A   C8     C Y N 15  
A   N7     N Y N 16  
A   C5     C Y N 17  
A   C6     C Y N 18  
A   N6     N N N 19  
A   N1     N Y N 20  
A   C2     C Y N 21  
A   N3     N Y N 22  
A   C4     C Y N 23  
A   HOP3   H N N 24  
A   HOP2   H N N 25  
A   "H5'"  H N N 26  
A   "H5''" H N N 27  
A   "H4'"  H N N 28  
A   "H3'"  H N N 29  
A   "HO3'" H N N 30  
A   "H2'"  H N N 31  
A   "HO2'" H N N 32  
A   "H1'"  H N N 33  
A   H8     H N N 34  
A   H61    H N N 35  
A   H62    H N N 36  
A   H2     H N N 37  
ALA N      N N N 38  
ALA CA     C N S 39  
ALA C      C N N 40  
ALA O      O N N 41  
ALA CB     C N N 42  
ALA OXT    O N N 43  
ALA H      H N N 44  
ALA H2     H N N 45  
ALA HA     H N N 46  
ALA HB1    H N N 47  
ALA HB2    H N N 48  
ALA HB3    H N N 49  
ALA HXT    H N N 50  
ARG N      N N N 51  
ARG CA     C N S 52  
ARG C      C N N 53  
ARG O      O N N 54  
ARG CB     C N N 55  
ARG CG     C N N 56  
ARG CD     C N N 57  
ARG NE     N N N 58  
ARG CZ     C N N 59  
ARG NH1    N N N 60  
ARG NH2    N N N 61  
ARG OXT    O N N 62  
ARG H      H N N 63  
ARG H2     H N N 64  
ARG HA     H N N 65  
ARG HB2    H N N 66  
ARG HB3    H N N 67  
ARG HG2    H N N 68  
ARG HG3    H N N 69  
ARG HD2    H N N 70  
ARG HD3    H N N 71  
ARG HE     H N N 72  
ARG HH11   H N N 73  
ARG HH12   H N N 74  
ARG HH21   H N N 75  
ARG HH22   H N N 76  
ARG HXT    H N N 77  
ASN N      N N N 78  
ASN CA     C N S 79  
ASN C      C N N 80  
ASN O      O N N 81  
ASN CB     C N N 82  
ASN CG     C N N 83  
ASN OD1    O N N 84  
ASN ND2    N N N 85  
ASN OXT    O N N 86  
ASN H      H N N 87  
ASN H2     H N N 88  
ASN HA     H N N 89  
ASN HB2    H N N 90  
ASN HB3    H N N 91  
ASN HD21   H N N 92  
ASN HD22   H N N 93  
ASN HXT    H N N 94  
ASP N      N N N 95  
ASP CA     C N S 96  
ASP C      C N N 97  
ASP O      O N N 98  
ASP CB     C N N 99  
ASP CG     C N N 100 
ASP OD1    O N N 101 
ASP OD2    O N N 102 
ASP OXT    O N N 103 
ASP H      H N N 104 
ASP H2     H N N 105 
ASP HA     H N N 106 
ASP HB2    H N N 107 
ASP HB3    H N N 108 
ASP HD2    H N N 109 
ASP HXT    H N N 110 
C   OP3    O N N 111 
C   P      P N N 112 
C   OP1    O N N 113 
C   OP2    O N N 114 
C   "O5'"  O N N 115 
C   "C5'"  C N N 116 
C   "C4'"  C N R 117 
C   "O4'"  O N N 118 
C   "C3'"  C N S 119 
C   "O3'"  O N N 120 
C   "C2'"  C N R 121 
C   "O2'"  O N N 122 
C   "C1'"  C N R 123 
C   N1     N N N 124 
C   C2     C N N 125 
C   O2     O N N 126 
C   N3     N N N 127 
C   C4     C N N 128 
C   N4     N N N 129 
C   C5     C N N 130 
C   C6     C N N 131 
C   HOP3   H N N 132 
C   HOP2   H N N 133 
C   "H5'"  H N N 134 
C   "H5''" H N N 135 
C   "H4'"  H N N 136 
C   "H3'"  H N N 137 
C   "HO3'" H N N 138 
C   "H2'"  H N N 139 
C   "HO2'" H N N 140 
C   "H1'"  H N N 141 
C   H41    H N N 142 
C   H42    H N N 143 
C   H5     H N N 144 
C   H6     H N N 145 
CYS N      N N N 146 
CYS CA     C N R 147 
CYS C      C N N 148 
CYS O      O N N 149 
CYS CB     C N N 150 
CYS SG     S N N 151 
CYS OXT    O N N 152 
CYS H      H N N 153 
CYS H2     H N N 154 
CYS HA     H N N 155 
CYS HB2    H N N 156 
CYS HB3    H N N 157 
CYS HG     H N N 158 
CYS HXT    H N N 159 
DA  OP3    O N N 160 
DA  P      P N N 161 
DA  OP1    O N N 162 
DA  OP2    O N N 163 
DA  "O5'"  O N N 164 
DA  "C5'"  C N N 165 
DA  "C4'"  C N R 166 
DA  "O4'"  O N N 167 
DA  "C3'"  C N S 168 
DA  "O3'"  O N N 169 
DA  "C2'"  C N N 170 
DA  "C1'"  C N R 171 
DA  N9     N Y N 172 
DA  C8     C Y N 173 
DA  N7     N Y N 174 
DA  C5     C Y N 175 
DA  C6     C Y N 176 
DA  N6     N N N 177 
DA  N1     N Y N 178 
DA  C2     C Y N 179 
DA  N3     N Y N 180 
DA  C4     C Y N 181 
DA  HOP3   H N N 182 
DA  HOP2   H N N 183 
DA  "H5'"  H N N 184 
DA  "H5''" H N N 185 
DA  "H4'"  H N N 186 
DA  "H3'"  H N N 187 
DA  "HO3'" H N N 188 
DA  "H2'"  H N N 189 
DA  "H2''" H N N 190 
DA  "H1'"  H N N 191 
DA  H8     H N N 192 
DA  H61    H N N 193 
DA  H62    H N N 194 
DA  H2     H N N 195 
DC  OP3    O N N 196 
DC  P      P N N 197 
DC  OP1    O N N 198 
DC  OP2    O N N 199 
DC  "O5'"  O N N 200 
DC  "C5'"  C N N 201 
DC  "C4'"  C N R 202 
DC  "O4'"  O N N 203 
DC  "C3'"  C N S 204 
DC  "O3'"  O N N 205 
DC  "C2'"  C N N 206 
DC  "C1'"  C N R 207 
DC  N1     N N N 208 
DC  C2     C N N 209 
DC  O2     O N N 210 
DC  N3     N N N 211 
DC  C4     C N N 212 
DC  N4     N N N 213 
DC  C5     C N N 214 
DC  C6     C N N 215 
DC  HOP3   H N N 216 
DC  HOP2   H N N 217 
DC  "H5'"  H N N 218 
DC  "H5''" H N N 219 
DC  "H4'"  H N N 220 
DC  "H3'"  H N N 221 
DC  "HO3'" H N N 222 
DC  "H2'"  H N N 223 
DC  "H2''" H N N 224 
DC  "H1'"  H N N 225 
DC  H41    H N N 226 
DC  H42    H N N 227 
DC  H5     H N N 228 
DC  H6     H N N 229 
DG  OP3    O N N 230 
DG  P      P N N 231 
DG  OP1    O N N 232 
DG  OP2    O N N 233 
DG  "O5'"  O N N 234 
DG  "C5'"  C N N 235 
DG  "C4'"  C N R 236 
DG  "O4'"  O N N 237 
DG  "C3'"  C N S 238 
DG  "O3'"  O N N 239 
DG  "C2'"  C N N 240 
DG  "C1'"  C N R 241 
DG  N9     N Y N 242 
DG  C8     C Y N 243 
DG  N7     N Y N 244 
DG  C5     C Y N 245 
DG  C6     C N N 246 
DG  O6     O N N 247 
DG  N1     N N N 248 
DG  C2     C N N 249 
DG  N2     N N N 250 
DG  N3     N N N 251 
DG  C4     C Y N 252 
DG  HOP3   H N N 253 
DG  HOP2   H N N 254 
DG  "H5'"  H N N 255 
DG  "H5''" H N N 256 
DG  "H4'"  H N N 257 
DG  "H3'"  H N N 258 
DG  "HO3'" H N N 259 
DG  "H2'"  H N N 260 
DG  "H2''" H N N 261 
DG  "H1'"  H N N 262 
DG  H8     H N N 263 
DG  H1     H N N 264 
DG  H21    H N N 265 
DG  H22    H N N 266 
DT  OP3    O N N 267 
DT  P      P N N 268 
DT  OP1    O N N 269 
DT  OP2    O N N 270 
DT  "O5'"  O N N 271 
DT  "C5'"  C N N 272 
DT  "C4'"  C N R 273 
DT  "O4'"  O N N 274 
DT  "C3'"  C N S 275 
DT  "O3'"  O N N 276 
DT  "C2'"  C N N 277 
DT  "C1'"  C N R 278 
DT  N1     N N N 279 
DT  C2     C N N 280 
DT  O2     O N N 281 
DT  N3     N N N 282 
DT  C4     C N N 283 
DT  O4     O N N 284 
DT  C5     C N N 285 
DT  C7     C N N 286 
DT  C6     C N N 287 
DT  HOP3   H N N 288 
DT  HOP2   H N N 289 
DT  "H5'"  H N N 290 
DT  "H5''" H N N 291 
DT  "H4'"  H N N 292 
DT  "H3'"  H N N 293 
DT  "HO3'" H N N 294 
DT  "H2'"  H N N 295 
DT  "H2''" H N N 296 
DT  "H1'"  H N N 297 
DT  H3     H N N 298 
DT  H71    H N N 299 
DT  H72    H N N 300 
DT  H73    H N N 301 
DT  H6     H N N 302 
G   OP3    O N N 303 
G   P      P N N 304 
G   OP1    O N N 305 
G   OP2    O N N 306 
G   "O5'"  O N N 307 
G   "C5'"  C N N 308 
G   "C4'"  C N R 309 
G   "O4'"  O N N 310 
G   "C3'"  C N S 311 
G   "O3'"  O N N 312 
G   "C2'"  C N R 313 
G   "O2'"  O N N 314 
G   "C1'"  C N R 315 
G   N9     N Y N 316 
G   C8     C Y N 317 
G   N7     N Y N 318 
G   C5     C Y N 319 
G   C6     C N N 320 
G   O6     O N N 321 
G   N1     N N N 322 
G   C2     C N N 323 
G   N2     N N N 324 
G   N3     N N N 325 
G   C4     C Y N 326 
G   HOP3   H N N 327 
G   HOP2   H N N 328 
G   "H5'"  H N N 329 
G   "H5''" H N N 330 
G   "H4'"  H N N 331 
G   "H3'"  H N N 332 
G   "HO3'" H N N 333 
G   "H2'"  H N N 334 
G   "HO2'" H N N 335 
G   "H1'"  H N N 336 
G   H8     H N N 337 
G   H1     H N N 338 
G   H21    H N N 339 
G   H22    H N N 340 
GLN N      N N N 341 
GLN CA     C N S 342 
GLN C      C N N 343 
GLN O      O N N 344 
GLN CB     C N N 345 
GLN CG     C N N 346 
GLN CD     C N N 347 
GLN OE1    O N N 348 
GLN NE2    N N N 349 
GLN OXT    O N N 350 
GLN H      H N N 351 
GLN H2     H N N 352 
GLN HA     H N N 353 
GLN HB2    H N N 354 
GLN HB3    H N N 355 
GLN HG2    H N N 356 
GLN HG3    H N N 357 
GLN HE21   H N N 358 
GLN HE22   H N N 359 
GLN HXT    H N N 360 
GLU N      N N N 361 
GLU CA     C N S 362 
GLU C      C N N 363 
GLU O      O N N 364 
GLU CB     C N N 365 
GLU CG     C N N 366 
GLU CD     C N N 367 
GLU OE1    O N N 368 
GLU OE2    O N N 369 
GLU OXT    O N N 370 
GLU H      H N N 371 
GLU H2     H N N 372 
GLU HA     H N N 373 
GLU HB2    H N N 374 
GLU HB3    H N N 375 
GLU HG2    H N N 376 
GLU HG3    H N N 377 
GLU HE2    H N N 378 
GLU HXT    H N N 379 
GLY N      N N N 380 
GLY CA     C N N 381 
GLY C      C N N 382 
GLY O      O N N 383 
GLY OXT    O N N 384 
GLY H      H N N 385 
GLY H2     H N N 386 
GLY HA2    H N N 387 
GLY HA3    H N N 388 
GLY HXT    H N N 389 
HIS N      N N N 390 
HIS CA     C N S 391 
HIS C      C N N 392 
HIS O      O N N 393 
HIS CB     C N N 394 
HIS CG     C Y N 395 
HIS ND1    N Y N 396 
HIS CD2    C Y N 397 
HIS CE1    C Y N 398 
HIS NE2    N Y N 399 
HIS OXT    O N N 400 
HIS H      H N N 401 
HIS H2     H N N 402 
HIS HA     H N N 403 
HIS HB2    H N N 404 
HIS HB3    H N N 405 
HIS HD1    H N N 406 
HIS HD2    H N N 407 
HIS HE1    H N N 408 
HIS HE2    H N N 409 
HIS HXT    H N N 410 
ILE N      N N N 411 
ILE CA     C N S 412 
ILE C      C N N 413 
ILE O      O N N 414 
ILE CB     C N S 415 
ILE CG1    C N N 416 
ILE CG2    C N N 417 
ILE CD1    C N N 418 
ILE OXT    O N N 419 
ILE H      H N N 420 
ILE H2     H N N 421 
ILE HA     H N N 422 
ILE HB     H N N 423 
ILE HG12   H N N 424 
ILE HG13   H N N 425 
ILE HG21   H N N 426 
ILE HG22   H N N 427 
ILE HG23   H N N 428 
ILE HD11   H N N 429 
ILE HD12   H N N 430 
ILE HD13   H N N 431 
ILE HXT    H N N 432 
LEU N      N N N 433 
LEU CA     C N S 434 
LEU C      C N N 435 
LEU O      O N N 436 
LEU CB     C N N 437 
LEU CG     C N N 438 
LEU CD1    C N N 439 
LEU CD2    C N N 440 
LEU OXT    O N N 441 
LEU H      H N N 442 
LEU H2     H N N 443 
LEU HA     H N N 444 
LEU HB2    H N N 445 
LEU HB3    H N N 446 
LEU HG     H N N 447 
LEU HD11   H N N 448 
LEU HD12   H N N 449 
LEU HD13   H N N 450 
LEU HD21   H N N 451 
LEU HD22   H N N 452 
LEU HD23   H N N 453 
LEU HXT    H N N 454 
LYS N      N N N 455 
LYS CA     C N S 456 
LYS C      C N N 457 
LYS O      O N N 458 
LYS CB     C N N 459 
LYS CG     C N N 460 
LYS CD     C N N 461 
LYS CE     C N N 462 
LYS NZ     N N N 463 
LYS OXT    O N N 464 
LYS H      H N N 465 
LYS H2     H N N 466 
LYS HA     H N N 467 
LYS HB2    H N N 468 
LYS HB3    H N N 469 
LYS HG2    H N N 470 
LYS HG3    H N N 471 
LYS HD2    H N N 472 
LYS HD3    H N N 473 
LYS HE2    H N N 474 
LYS HE3    H N N 475 
LYS HZ1    H N N 476 
LYS HZ2    H N N 477 
LYS HZ3    H N N 478 
LYS HXT    H N N 479 
MET N      N N N 480 
MET CA     C N S 481 
MET C      C N N 482 
MET O      O N N 483 
MET CB     C N N 484 
MET CG     C N N 485 
MET SD     S N N 486 
MET CE     C N N 487 
MET OXT    O N N 488 
MET H      H N N 489 
MET H2     H N N 490 
MET HA     H N N 491 
MET HB2    H N N 492 
MET HB3    H N N 493 
MET HG2    H N N 494 
MET HG3    H N N 495 
MET HE1    H N N 496 
MET HE2    H N N 497 
MET HE3    H N N 498 
MET HXT    H N N 499 
PHE N      N N N 500 
PHE CA     C N S 501 
PHE C      C N N 502 
PHE O      O N N 503 
PHE CB     C N N 504 
PHE CG     C Y N 505 
PHE CD1    C Y N 506 
PHE CD2    C Y N 507 
PHE CE1    C Y N 508 
PHE CE2    C Y N 509 
PHE CZ     C Y N 510 
PHE OXT    O N N 511 
PHE H      H N N 512 
PHE H2     H N N 513 
PHE HA     H N N 514 
PHE HB2    H N N 515 
PHE HB3    H N N 516 
PHE HD1    H N N 517 
PHE HD2    H N N 518 
PHE HE1    H N N 519 
PHE HE2    H N N 520 
PHE HZ     H N N 521 
PHE HXT    H N N 522 
PRO N      N N N 523 
PRO CA     C N S 524 
PRO C      C N N 525 
PRO O      O N N 526 
PRO CB     C N N 527 
PRO CG     C N N 528 
PRO CD     C N N 529 
PRO OXT    O N N 530 
PRO H      H N N 531 
PRO HA     H N N 532 
PRO HB2    H N N 533 
PRO HB3    H N N 534 
PRO HG2    H N N 535 
PRO HG3    H N N 536 
PRO HD2    H N N 537 
PRO HD3    H N N 538 
PRO HXT    H N N 539 
SER N      N N N 540 
SER CA     C N S 541 
SER C      C N N 542 
SER O      O N N 543 
SER CB     C N N 544 
SER OG     O N N 545 
SER OXT    O N N 546 
SER H      H N N 547 
SER H2     H N N 548 
SER HA     H N N 549 
SER HB2    H N N 550 
SER HB3    H N N 551 
SER HG     H N N 552 
SER HXT    H N N 553 
THR N      N N N 554 
THR CA     C N S 555 
THR C      C N N 556 
THR O      O N N 557 
THR CB     C N R 558 
THR OG1    O N N 559 
THR CG2    C N N 560 
THR OXT    O N N 561 
THR H      H N N 562 
THR H2     H N N 563 
THR HA     H N N 564 
THR HB     H N N 565 
THR HG1    H N N 566 
THR HG21   H N N 567 
THR HG22   H N N 568 
THR HG23   H N N 569 
THR HXT    H N N 570 
TRP N      N N N 571 
TRP CA     C N S 572 
TRP C      C N N 573 
TRP O      O N N 574 
TRP CB     C N N 575 
TRP CG     C Y N 576 
TRP CD1    C Y N 577 
TRP CD2    C Y N 578 
TRP NE1    N Y N 579 
TRP CE2    C Y N 580 
TRP CE3    C Y N 581 
TRP CZ2    C Y N 582 
TRP CZ3    C Y N 583 
TRP CH2    C Y N 584 
TRP OXT    O N N 585 
TRP H      H N N 586 
TRP H2     H N N 587 
TRP HA     H N N 588 
TRP HB2    H N N 589 
TRP HB3    H N N 590 
TRP HD1    H N N 591 
TRP HE1    H N N 592 
TRP HE3    H N N 593 
TRP HZ2    H N N 594 
TRP HZ3    H N N 595 
TRP HH2    H N N 596 
TRP HXT    H N N 597 
TYR N      N N N 598 
TYR CA     C N S 599 
TYR C      C N N 600 
TYR O      O N N 601 
TYR CB     C N N 602 
TYR CG     C Y N 603 
TYR CD1    C Y N 604 
TYR CD2    C Y N 605 
TYR CE1    C Y N 606 
TYR CE2    C Y N 607 
TYR CZ     C Y N 608 
TYR OH     O N N 609 
TYR OXT    O N N 610 
TYR H      H N N 611 
TYR H2     H N N 612 
TYR HA     H N N 613 
TYR HB2    H N N 614 
TYR HB3    H N N 615 
TYR HD1    H N N 616 
TYR HD2    H N N 617 
TYR HE1    H N N 618 
TYR HE2    H N N 619 
TYR HH     H N N 620 
TYR HXT    H N N 621 
U   OP3    O N N 622 
U   P      P N N 623 
U   OP1    O N N 624 
U   OP2    O N N 625 
U   "O5'"  O N N 626 
U   "C5'"  C N N 627 
U   "C4'"  C N R 628 
U   "O4'"  O N N 629 
U   "C3'"  C N S 630 
U   "O3'"  O N N 631 
U   "C2'"  C N R 632 
U   "O2'"  O N N 633 
U   "C1'"  C N R 634 
U   N1     N N N 635 
U   C2     C N N 636 
U   O2     O N N 637 
U   N3     N N N 638 
U   C4     C N N 639 
U   O4     O N N 640 
U   C5     C N N 641 
U   C6     C N N 642 
U   HOP3   H N N 643 
U   HOP2   H N N 644 
U   "H5'"  H N N 645 
U   "H5''" H N N 646 
U   "H4'"  H N N 647 
U   "H3'"  H N N 648 
U   "HO3'" H N N 649 
U   "H2'"  H N N 650 
U   "HO2'" H N N 651 
U   "H1'"  H N N 652 
U   H3     H N N 653 
U   H5     H N N 654 
U   H6     H N N 655 
VAL N      N N N 656 
VAL CA     C N S 657 
VAL C      C N N 658 
VAL O      O N N 659 
VAL CB     C N N 660 
VAL CG1    C N N 661 
VAL CG2    C N N 662 
VAL OXT    O N N 663 
VAL H      H N N 664 
VAL H2     H N N 665 
VAL HA     H N N 666 
VAL HB     H N N 667 
VAL HG11   H N N 668 
VAL HG12   H N N 669 
VAL HG13   H N N 670 
VAL HG21   H N N 671 
VAL HG22   H N N 672 
VAL HG23   H N N 673 
VAL HXT    H N N 674 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A   OP3   P      sing N N 1   
A   OP3   HOP3   sing N N 2   
A   P     OP1    doub N N 3   
A   P     OP2    sing N N 4   
A   P     "O5'"  sing N N 5   
A   OP2   HOP2   sing N N 6   
A   "O5'" "C5'"  sing N N 7   
A   "C5'" "C4'"  sing N N 8   
A   "C5'" "H5'"  sing N N 9   
A   "C5'" "H5''" sing N N 10  
A   "C4'" "O4'"  sing N N 11  
A   "C4'" "C3'"  sing N N 12  
A   "C4'" "H4'"  sing N N 13  
A   "O4'" "C1'"  sing N N 14  
A   "C3'" "O3'"  sing N N 15  
A   "C3'" "C2'"  sing N N 16  
A   "C3'" "H3'"  sing N N 17  
A   "O3'" "HO3'" sing N N 18  
A   "C2'" "O2'"  sing N N 19  
A   "C2'" "C1'"  sing N N 20  
A   "C2'" "H2'"  sing N N 21  
A   "O2'" "HO2'" sing N N 22  
A   "C1'" N9     sing N N 23  
A   "C1'" "H1'"  sing N N 24  
A   N9    C8     sing Y N 25  
A   N9    C4     sing Y N 26  
A   C8    N7     doub Y N 27  
A   C8    H8     sing N N 28  
A   N7    C5     sing Y N 29  
A   C5    C6     sing Y N 30  
A   C5    C4     doub Y N 31  
A   C6    N6     sing N N 32  
A   C6    N1     doub Y N 33  
A   N6    H61    sing N N 34  
A   N6    H62    sing N N 35  
A   N1    C2     sing Y N 36  
A   C2    N3     doub Y N 37  
A   C2    H2     sing N N 38  
A   N3    C4     sing Y N 39  
ALA N     CA     sing N N 40  
ALA N     H      sing N N 41  
ALA N     H2     sing N N 42  
ALA CA    C      sing N N 43  
ALA CA    CB     sing N N 44  
ALA CA    HA     sing N N 45  
ALA C     O      doub N N 46  
ALA C     OXT    sing N N 47  
ALA CB    HB1    sing N N 48  
ALA CB    HB2    sing N N 49  
ALA CB    HB3    sing N N 50  
ALA OXT   HXT    sing N N 51  
ARG N     CA     sing N N 52  
ARG N     H      sing N N 53  
ARG N     H2     sing N N 54  
ARG CA    C      sing N N 55  
ARG CA    CB     sing N N 56  
ARG CA    HA     sing N N 57  
ARG C     O      doub N N 58  
ARG C     OXT    sing N N 59  
ARG CB    CG     sing N N 60  
ARG CB    HB2    sing N N 61  
ARG CB    HB3    sing N N 62  
ARG CG    CD     sing N N 63  
ARG CG    HG2    sing N N 64  
ARG CG    HG3    sing N N 65  
ARG CD    NE     sing N N 66  
ARG CD    HD2    sing N N 67  
ARG CD    HD3    sing N N 68  
ARG NE    CZ     sing N N 69  
ARG NE    HE     sing N N 70  
ARG CZ    NH1    sing N N 71  
ARG CZ    NH2    doub N N 72  
ARG NH1   HH11   sing N N 73  
ARG NH1   HH12   sing N N 74  
ARG NH2   HH21   sing N N 75  
ARG NH2   HH22   sing N N 76  
ARG OXT   HXT    sing N N 77  
ASN N     CA     sing N N 78  
ASN N     H      sing N N 79  
ASN N     H2     sing N N 80  
ASN CA    C      sing N N 81  
ASN CA    CB     sing N N 82  
ASN CA    HA     sing N N 83  
ASN C     O      doub N N 84  
ASN C     OXT    sing N N 85  
ASN CB    CG     sing N N 86  
ASN CB    HB2    sing N N 87  
ASN CB    HB3    sing N N 88  
ASN CG    OD1    doub N N 89  
ASN CG    ND2    sing N N 90  
ASN ND2   HD21   sing N N 91  
ASN ND2   HD22   sing N N 92  
ASN OXT   HXT    sing N N 93  
ASP N     CA     sing N N 94  
ASP N     H      sing N N 95  
ASP N     H2     sing N N 96  
ASP CA    C      sing N N 97  
ASP CA    CB     sing N N 98  
ASP CA    HA     sing N N 99  
ASP C     O      doub N N 100 
ASP C     OXT    sing N N 101 
ASP CB    CG     sing N N 102 
ASP CB    HB2    sing N N 103 
ASP CB    HB3    sing N N 104 
ASP CG    OD1    doub N N 105 
ASP CG    OD2    sing N N 106 
ASP OD2   HD2    sing N N 107 
ASP OXT   HXT    sing N N 108 
C   OP3   P      sing N N 109 
C   OP3   HOP3   sing N N 110 
C   P     OP1    doub N N 111 
C   P     OP2    sing N N 112 
C   P     "O5'"  sing N N 113 
C   OP2   HOP2   sing N N 114 
C   "O5'" "C5'"  sing N N 115 
C   "C5'" "C4'"  sing N N 116 
C   "C5'" "H5'"  sing N N 117 
C   "C5'" "H5''" sing N N 118 
C   "C4'" "O4'"  sing N N 119 
C   "C4'" "C3'"  sing N N 120 
C   "C4'" "H4'"  sing N N 121 
C   "O4'" "C1'"  sing N N 122 
C   "C3'" "O3'"  sing N N 123 
C   "C3'" "C2'"  sing N N 124 
C   "C3'" "H3'"  sing N N 125 
C   "O3'" "HO3'" sing N N 126 
C   "C2'" "O2'"  sing N N 127 
C   "C2'" "C1'"  sing N N 128 
C   "C2'" "H2'"  sing N N 129 
C   "O2'" "HO2'" sing N N 130 
C   "C1'" N1     sing N N 131 
C   "C1'" "H1'"  sing N N 132 
C   N1    C2     sing N N 133 
C   N1    C6     sing N N 134 
C   C2    O2     doub N N 135 
C   C2    N3     sing N N 136 
C   N3    C4     doub N N 137 
C   C4    N4     sing N N 138 
C   C4    C5     sing N N 139 
C   N4    H41    sing N N 140 
C   N4    H42    sing N N 141 
C   C5    C6     doub N N 142 
C   C5    H5     sing N N 143 
C   C6    H6     sing N N 144 
CYS N     CA     sing N N 145 
CYS N     H      sing N N 146 
CYS N     H2     sing N N 147 
CYS CA    C      sing N N 148 
CYS CA    CB     sing N N 149 
CYS CA    HA     sing N N 150 
CYS C     O      doub N N 151 
CYS C     OXT    sing N N 152 
CYS CB    SG     sing N N 153 
CYS CB    HB2    sing N N 154 
CYS CB    HB3    sing N N 155 
CYS SG    HG     sing N N 156 
CYS OXT   HXT    sing N N 157 
DA  OP3   P      sing N N 158 
DA  OP3   HOP3   sing N N 159 
DA  P     OP1    doub N N 160 
DA  P     OP2    sing N N 161 
DA  P     "O5'"  sing N N 162 
DA  OP2   HOP2   sing N N 163 
DA  "O5'" "C5'"  sing N N 164 
DA  "C5'" "C4'"  sing N N 165 
DA  "C5'" "H5'"  sing N N 166 
DA  "C5'" "H5''" sing N N 167 
DA  "C4'" "O4'"  sing N N 168 
DA  "C4'" "C3'"  sing N N 169 
DA  "C4'" "H4'"  sing N N 170 
DA  "O4'" "C1'"  sing N N 171 
DA  "C3'" "O3'"  sing N N 172 
DA  "C3'" "C2'"  sing N N 173 
DA  "C3'" "H3'"  sing N N 174 
DA  "O3'" "HO3'" sing N N 175 
DA  "C2'" "C1'"  sing N N 176 
DA  "C2'" "H2'"  sing N N 177 
DA  "C2'" "H2''" sing N N 178 
DA  "C1'" N9     sing N N 179 
DA  "C1'" "H1'"  sing N N 180 
DA  N9    C8     sing Y N 181 
DA  N9    C4     sing Y N 182 
DA  C8    N7     doub Y N 183 
DA  C8    H8     sing N N 184 
DA  N7    C5     sing Y N 185 
DA  C5    C6     sing Y N 186 
DA  C5    C4     doub Y N 187 
DA  C6    N6     sing N N 188 
DA  C6    N1     doub Y N 189 
DA  N6    H61    sing N N 190 
DA  N6    H62    sing N N 191 
DA  N1    C2     sing Y N 192 
DA  C2    N3     doub Y N 193 
DA  C2    H2     sing N N 194 
DA  N3    C4     sing Y N 195 
DC  OP3   P      sing N N 196 
DC  OP3   HOP3   sing N N 197 
DC  P     OP1    doub N N 198 
DC  P     OP2    sing N N 199 
DC  P     "O5'"  sing N N 200 
DC  OP2   HOP2   sing N N 201 
DC  "O5'" "C5'"  sing N N 202 
DC  "C5'" "C4'"  sing N N 203 
DC  "C5'" "H5'"  sing N N 204 
DC  "C5'" "H5''" sing N N 205 
DC  "C4'" "O4'"  sing N N 206 
DC  "C4'" "C3'"  sing N N 207 
DC  "C4'" "H4'"  sing N N 208 
DC  "O4'" "C1'"  sing N N 209 
DC  "C3'" "O3'"  sing N N 210 
DC  "C3'" "C2'"  sing N N 211 
DC  "C3'" "H3'"  sing N N 212 
DC  "O3'" "HO3'" sing N N 213 
DC  "C2'" "C1'"  sing N N 214 
DC  "C2'" "H2'"  sing N N 215 
DC  "C2'" "H2''" sing N N 216 
DC  "C1'" N1     sing N N 217 
DC  "C1'" "H1'"  sing N N 218 
DC  N1    C2     sing N N 219 
DC  N1    C6     sing N N 220 
DC  C2    O2     doub N N 221 
DC  C2    N3     sing N N 222 
DC  N3    C4     doub N N 223 
DC  C4    N4     sing N N 224 
DC  C4    C5     sing N N 225 
DC  N4    H41    sing N N 226 
DC  N4    H42    sing N N 227 
DC  C5    C6     doub N N 228 
DC  C5    H5     sing N N 229 
DC  C6    H6     sing N N 230 
DG  OP3   P      sing N N 231 
DG  OP3   HOP3   sing N N 232 
DG  P     OP1    doub N N 233 
DG  P     OP2    sing N N 234 
DG  P     "O5'"  sing N N 235 
DG  OP2   HOP2   sing N N 236 
DG  "O5'" "C5'"  sing N N 237 
DG  "C5'" "C4'"  sing N N 238 
DG  "C5'" "H5'"  sing N N 239 
DG  "C5'" "H5''" sing N N 240 
DG  "C4'" "O4'"  sing N N 241 
DG  "C4'" "C3'"  sing N N 242 
DG  "C4'" "H4'"  sing N N 243 
DG  "O4'" "C1'"  sing N N 244 
DG  "C3'" "O3'"  sing N N 245 
DG  "C3'" "C2'"  sing N N 246 
DG  "C3'" "H3'"  sing N N 247 
DG  "O3'" "HO3'" sing N N 248 
DG  "C2'" "C1'"  sing N N 249 
DG  "C2'" "H2'"  sing N N 250 
DG  "C2'" "H2''" sing N N 251 
DG  "C1'" N9     sing N N 252 
DG  "C1'" "H1'"  sing N N 253 
DG  N9    C8     sing Y N 254 
DG  N9    C4     sing Y N 255 
DG  C8    N7     doub Y N 256 
DG  C8    H8     sing N N 257 
DG  N7    C5     sing Y N 258 
DG  C5    C6     sing N N 259 
DG  C5    C4     doub Y N 260 
DG  C6    O6     doub N N 261 
DG  C6    N1     sing N N 262 
DG  N1    C2     sing N N 263 
DG  N1    H1     sing N N 264 
DG  C2    N2     sing N N 265 
DG  C2    N3     doub N N 266 
DG  N2    H21    sing N N 267 
DG  N2    H22    sing N N 268 
DG  N3    C4     sing N N 269 
DT  OP3   P      sing N N 270 
DT  OP3   HOP3   sing N N 271 
DT  P     OP1    doub N N 272 
DT  P     OP2    sing N N 273 
DT  P     "O5'"  sing N N 274 
DT  OP2   HOP2   sing N N 275 
DT  "O5'" "C5'"  sing N N 276 
DT  "C5'" "C4'"  sing N N 277 
DT  "C5'" "H5'"  sing N N 278 
DT  "C5'" "H5''" sing N N 279 
DT  "C4'" "O4'"  sing N N 280 
DT  "C4'" "C3'"  sing N N 281 
DT  "C4'" "H4'"  sing N N 282 
DT  "O4'" "C1'"  sing N N 283 
DT  "C3'" "O3'"  sing N N 284 
DT  "C3'" "C2'"  sing N N 285 
DT  "C3'" "H3'"  sing N N 286 
DT  "O3'" "HO3'" sing N N 287 
DT  "C2'" "C1'"  sing N N 288 
DT  "C2'" "H2'"  sing N N 289 
DT  "C2'" "H2''" sing N N 290 
DT  "C1'" N1     sing N N 291 
DT  "C1'" "H1'"  sing N N 292 
DT  N1    C2     sing N N 293 
DT  N1    C6     sing N N 294 
DT  C2    O2     doub N N 295 
DT  C2    N3     sing N N 296 
DT  N3    C4     sing N N 297 
DT  N3    H3     sing N N 298 
DT  C4    O4     doub N N 299 
DT  C4    C5     sing N N 300 
DT  C5    C7     sing N N 301 
DT  C5    C6     doub N N 302 
DT  C7    H71    sing N N 303 
DT  C7    H72    sing N N 304 
DT  C7    H73    sing N N 305 
DT  C6    H6     sing N N 306 
G   OP3   P      sing N N 307 
G   OP3   HOP3   sing N N 308 
G   P     OP1    doub N N 309 
G   P     OP2    sing N N 310 
G   P     "O5'"  sing N N 311 
G   OP2   HOP2   sing N N 312 
G   "O5'" "C5'"  sing N N 313 
G   "C5'" "C4'"  sing N N 314 
G   "C5'" "H5'"  sing N N 315 
G   "C5'" "H5''" sing N N 316 
G   "C4'" "O4'"  sing N N 317 
G   "C4'" "C3'"  sing N N 318 
G   "C4'" "H4'"  sing N N 319 
G   "O4'" "C1'"  sing N N 320 
G   "C3'" "O3'"  sing N N 321 
G   "C3'" "C2'"  sing N N 322 
G   "C3'" "H3'"  sing N N 323 
G   "O3'" "HO3'" sing N N 324 
G   "C2'" "O2'"  sing N N 325 
G   "C2'" "C1'"  sing N N 326 
G   "C2'" "H2'"  sing N N 327 
G   "O2'" "HO2'" sing N N 328 
G   "C1'" N9     sing N N 329 
G   "C1'" "H1'"  sing N N 330 
G   N9    C8     sing Y N 331 
G   N9    C4     sing Y N 332 
G   C8    N7     doub Y N 333 
G   C8    H8     sing N N 334 
G   N7    C5     sing Y N 335 
G   C5    C6     sing N N 336 
G   C5    C4     doub Y N 337 
G   C6    O6     doub N N 338 
G   C6    N1     sing N N 339 
G   N1    C2     sing N N 340 
G   N1    H1     sing N N 341 
G   C2    N2     sing N N 342 
G   C2    N3     doub N N 343 
G   N2    H21    sing N N 344 
G   N2    H22    sing N N 345 
G   N3    C4     sing N N 346 
GLN N     CA     sing N N 347 
GLN N     H      sing N N 348 
GLN N     H2     sing N N 349 
GLN CA    C      sing N N 350 
GLN CA    CB     sing N N 351 
GLN CA    HA     sing N N 352 
GLN C     O      doub N N 353 
GLN C     OXT    sing N N 354 
GLN CB    CG     sing N N 355 
GLN CB    HB2    sing N N 356 
GLN CB    HB3    sing N N 357 
GLN CG    CD     sing N N 358 
GLN CG    HG2    sing N N 359 
GLN CG    HG3    sing N N 360 
GLN CD    OE1    doub N N 361 
GLN CD    NE2    sing N N 362 
GLN NE2   HE21   sing N N 363 
GLN NE2   HE22   sing N N 364 
GLN OXT   HXT    sing N N 365 
GLU N     CA     sing N N 366 
GLU N     H      sing N N 367 
GLU N     H2     sing N N 368 
GLU CA    C      sing N N 369 
GLU CA    CB     sing N N 370 
GLU CA    HA     sing N N 371 
GLU C     O      doub N N 372 
GLU C     OXT    sing N N 373 
GLU CB    CG     sing N N 374 
GLU CB    HB2    sing N N 375 
GLU CB    HB3    sing N N 376 
GLU CG    CD     sing N N 377 
GLU CG    HG2    sing N N 378 
GLU CG    HG3    sing N N 379 
GLU CD    OE1    doub N N 380 
GLU CD    OE2    sing N N 381 
GLU OE2   HE2    sing N N 382 
GLU OXT   HXT    sing N N 383 
GLY N     CA     sing N N 384 
GLY N     H      sing N N 385 
GLY N     H2     sing N N 386 
GLY CA    C      sing N N 387 
GLY CA    HA2    sing N N 388 
GLY CA    HA3    sing N N 389 
GLY C     O      doub N N 390 
GLY C     OXT    sing N N 391 
GLY OXT   HXT    sing N N 392 
HIS N     CA     sing N N 393 
HIS N     H      sing N N 394 
HIS N     H2     sing N N 395 
HIS CA    C      sing N N 396 
HIS CA    CB     sing N N 397 
HIS CA    HA     sing N N 398 
HIS C     O      doub N N 399 
HIS C     OXT    sing N N 400 
HIS CB    CG     sing N N 401 
HIS CB    HB2    sing N N 402 
HIS CB    HB3    sing N N 403 
HIS CG    ND1    sing Y N 404 
HIS CG    CD2    doub Y N 405 
HIS ND1   CE1    doub Y N 406 
HIS ND1   HD1    sing N N 407 
HIS CD2   NE2    sing Y N 408 
HIS CD2   HD2    sing N N 409 
HIS CE1   NE2    sing Y N 410 
HIS CE1   HE1    sing N N 411 
HIS NE2   HE2    sing N N 412 
HIS OXT   HXT    sing N N 413 
ILE N     CA     sing N N 414 
ILE N     H      sing N N 415 
ILE N     H2     sing N N 416 
ILE CA    C      sing N N 417 
ILE CA    CB     sing N N 418 
ILE CA    HA     sing N N 419 
ILE C     O      doub N N 420 
ILE C     OXT    sing N N 421 
ILE CB    CG1    sing N N 422 
ILE CB    CG2    sing N N 423 
ILE CB    HB     sing N N 424 
ILE CG1   CD1    sing N N 425 
ILE CG1   HG12   sing N N 426 
ILE CG1   HG13   sing N N 427 
ILE CG2   HG21   sing N N 428 
ILE CG2   HG22   sing N N 429 
ILE CG2   HG23   sing N N 430 
ILE CD1   HD11   sing N N 431 
ILE CD1   HD12   sing N N 432 
ILE CD1   HD13   sing N N 433 
ILE OXT   HXT    sing N N 434 
LEU N     CA     sing N N 435 
LEU N     H      sing N N 436 
LEU N     H2     sing N N 437 
LEU CA    C      sing N N 438 
LEU CA    CB     sing N N 439 
LEU CA    HA     sing N N 440 
LEU C     O      doub N N 441 
LEU C     OXT    sing N N 442 
LEU CB    CG     sing N N 443 
LEU CB    HB2    sing N N 444 
LEU CB    HB3    sing N N 445 
LEU CG    CD1    sing N N 446 
LEU CG    CD2    sing N N 447 
LEU CG    HG     sing N N 448 
LEU CD1   HD11   sing N N 449 
LEU CD1   HD12   sing N N 450 
LEU CD1   HD13   sing N N 451 
LEU CD2   HD21   sing N N 452 
LEU CD2   HD22   sing N N 453 
LEU CD2   HD23   sing N N 454 
LEU OXT   HXT    sing N N 455 
LYS N     CA     sing N N 456 
LYS N     H      sing N N 457 
LYS N     H2     sing N N 458 
LYS CA    C      sing N N 459 
LYS CA    CB     sing N N 460 
LYS CA    HA     sing N N 461 
LYS C     O      doub N N 462 
LYS C     OXT    sing N N 463 
LYS CB    CG     sing N N 464 
LYS CB    HB2    sing N N 465 
LYS CB    HB3    sing N N 466 
LYS CG    CD     sing N N 467 
LYS CG    HG2    sing N N 468 
LYS CG    HG3    sing N N 469 
LYS CD    CE     sing N N 470 
LYS CD    HD2    sing N N 471 
LYS CD    HD3    sing N N 472 
LYS CE    NZ     sing N N 473 
LYS CE    HE2    sing N N 474 
LYS CE    HE3    sing N N 475 
LYS NZ    HZ1    sing N N 476 
LYS NZ    HZ2    sing N N 477 
LYS NZ    HZ3    sing N N 478 
LYS OXT   HXT    sing N N 479 
MET N     CA     sing N N 480 
MET N     H      sing N N 481 
MET N     H2     sing N N 482 
MET CA    C      sing N N 483 
MET CA    CB     sing N N 484 
MET CA    HA     sing N N 485 
MET C     O      doub N N 486 
MET C     OXT    sing N N 487 
MET CB    CG     sing N N 488 
MET CB    HB2    sing N N 489 
MET CB    HB3    sing N N 490 
MET CG    SD     sing N N 491 
MET CG    HG2    sing N N 492 
MET CG    HG3    sing N N 493 
MET SD    CE     sing N N 494 
MET CE    HE1    sing N N 495 
MET CE    HE2    sing N N 496 
MET CE    HE3    sing N N 497 
MET OXT   HXT    sing N N 498 
PHE N     CA     sing N N 499 
PHE N     H      sing N N 500 
PHE N     H2     sing N N 501 
PHE CA    C      sing N N 502 
PHE CA    CB     sing N N 503 
PHE CA    HA     sing N N 504 
PHE C     O      doub N N 505 
PHE C     OXT    sing N N 506 
PHE CB    CG     sing N N 507 
PHE CB    HB2    sing N N 508 
PHE CB    HB3    sing N N 509 
PHE CG    CD1    doub Y N 510 
PHE CG    CD2    sing Y N 511 
PHE CD1   CE1    sing Y N 512 
PHE CD1   HD1    sing N N 513 
PHE CD2   CE2    doub Y N 514 
PHE CD2   HD2    sing N N 515 
PHE CE1   CZ     doub Y N 516 
PHE CE1   HE1    sing N N 517 
PHE CE2   CZ     sing Y N 518 
PHE CE2   HE2    sing N N 519 
PHE CZ    HZ     sing N N 520 
PHE OXT   HXT    sing N N 521 
PRO N     CA     sing N N 522 
PRO N     CD     sing N N 523 
PRO N     H      sing N N 524 
PRO CA    C      sing N N 525 
PRO CA    CB     sing N N 526 
PRO CA    HA     sing N N 527 
PRO C     O      doub N N 528 
PRO C     OXT    sing N N 529 
PRO CB    CG     sing N N 530 
PRO CB    HB2    sing N N 531 
PRO CB    HB3    sing N N 532 
PRO CG    CD     sing N N 533 
PRO CG    HG2    sing N N 534 
PRO CG    HG3    sing N N 535 
PRO CD    HD2    sing N N 536 
PRO CD    HD3    sing N N 537 
PRO OXT   HXT    sing N N 538 
SER N     CA     sing N N 539 
SER N     H      sing N N 540 
SER N     H2     sing N N 541 
SER CA    C      sing N N 542 
SER CA    CB     sing N N 543 
SER CA    HA     sing N N 544 
SER C     O      doub N N 545 
SER C     OXT    sing N N 546 
SER CB    OG     sing N N 547 
SER CB    HB2    sing N N 548 
SER CB    HB3    sing N N 549 
SER OG    HG     sing N N 550 
SER OXT   HXT    sing N N 551 
THR N     CA     sing N N 552 
THR N     H      sing N N 553 
THR N     H2     sing N N 554 
THR CA    C      sing N N 555 
THR CA    CB     sing N N 556 
THR CA    HA     sing N N 557 
THR C     O      doub N N 558 
THR C     OXT    sing N N 559 
THR CB    OG1    sing N N 560 
THR CB    CG2    sing N N 561 
THR CB    HB     sing N N 562 
THR OG1   HG1    sing N N 563 
THR CG2   HG21   sing N N 564 
THR CG2   HG22   sing N N 565 
THR CG2   HG23   sing N N 566 
THR OXT   HXT    sing N N 567 
TRP N     CA     sing N N 568 
TRP N     H      sing N N 569 
TRP N     H2     sing N N 570 
TRP CA    C      sing N N 571 
TRP CA    CB     sing N N 572 
TRP CA    HA     sing N N 573 
TRP C     O      doub N N 574 
TRP C     OXT    sing N N 575 
TRP CB    CG     sing N N 576 
TRP CB    HB2    sing N N 577 
TRP CB    HB3    sing N N 578 
TRP CG    CD1    doub Y N 579 
TRP CG    CD2    sing Y N 580 
TRP CD1   NE1    sing Y N 581 
TRP CD1   HD1    sing N N 582 
TRP CD2   CE2    doub Y N 583 
TRP CD2   CE3    sing Y N 584 
TRP NE1   CE2    sing Y N 585 
TRP NE1   HE1    sing N N 586 
TRP CE2   CZ2    sing Y N 587 
TRP CE3   CZ3    doub Y N 588 
TRP CE3   HE3    sing N N 589 
TRP CZ2   CH2    doub Y N 590 
TRP CZ2   HZ2    sing N N 591 
TRP CZ3   CH2    sing Y N 592 
TRP CZ3   HZ3    sing N N 593 
TRP CH2   HH2    sing N N 594 
TRP OXT   HXT    sing N N 595 
TYR N     CA     sing N N 596 
TYR N     H      sing N N 597 
TYR N     H2     sing N N 598 
TYR CA    C      sing N N 599 
TYR CA    CB     sing N N 600 
TYR CA    HA     sing N N 601 
TYR C     O      doub N N 602 
TYR C     OXT    sing N N 603 
TYR CB    CG     sing N N 604 
TYR CB    HB2    sing N N 605 
TYR CB    HB3    sing N N 606 
TYR CG    CD1    doub Y N 607 
TYR CG    CD2    sing Y N 608 
TYR CD1   CE1    sing Y N 609 
TYR CD1   HD1    sing N N 610 
TYR CD2   CE2    doub Y N 611 
TYR CD2   HD2    sing N N 612 
TYR CE1   CZ     doub Y N 613 
TYR CE1   HE1    sing N N 614 
TYR CE2   CZ     sing Y N 615 
TYR CE2   HE2    sing N N 616 
TYR CZ    OH     sing N N 617 
TYR OH    HH     sing N N 618 
TYR OXT   HXT    sing N N 619 
U   OP3   P      sing N N 620 
U   OP3   HOP3   sing N N 621 
U   P     OP1    doub N N 622 
U   P     OP2    sing N N 623 
U   P     "O5'"  sing N N 624 
U   OP2   HOP2   sing N N 625 
U   "O5'" "C5'"  sing N N 626 
U   "C5'" "C4'"  sing N N 627 
U   "C5'" "H5'"  sing N N 628 
U   "C5'" "H5''" sing N N 629 
U   "C4'" "O4'"  sing N N 630 
U   "C4'" "C3'"  sing N N 631 
U   "C4'" "H4'"  sing N N 632 
U   "O4'" "C1'"  sing N N 633 
U   "C3'" "O3'"  sing N N 634 
U   "C3'" "C2'"  sing N N 635 
U   "C3'" "H3'"  sing N N 636 
U   "O3'" "HO3'" sing N N 637 
U   "C2'" "O2'"  sing N N 638 
U   "C2'" "C1'"  sing N N 639 
U   "C2'" "H2'"  sing N N 640 
U   "O2'" "HO2'" sing N N 641 
U   "C1'" N1     sing N N 642 
U   "C1'" "H1'"  sing N N 643 
U   N1    C2     sing N N 644 
U   N1    C6     sing N N 645 
U   C2    O2     doub N N 646 
U   C2    N3     sing N N 647 
U   N3    C4     sing N N 648 
U   N3    H3     sing N N 649 
U   C4    O4     doub N N 650 
U   C4    C5     sing N N 651 
U   C5    C6     doub N N 652 
U   C5    H5     sing N N 653 
U   C6    H6     sing N N 654 
VAL N     CA     sing N N 655 
VAL N     H      sing N N 656 
VAL N     H2     sing N N 657 
VAL CA    C      sing N N 658 
VAL CA    CB     sing N N 659 
VAL CA    HA     sing N N 660 
VAL C     O      doub N N 661 
VAL C     OXT    sing N N 662 
VAL CB    CG1    sing N N 663 
VAL CB    CG2    sing N N 664 
VAL CB    HB     sing N N 665 
VAL CG1   HG11   sing N N 666 
VAL CG1   HG12   sing N N 667 
VAL CG1   HG13   sing N N 668 
VAL CG2   HG21   sing N N 669 
VAL CG2   HG22   sing N N 670 
VAL CG2   HG23   sing N N 671 
VAL OXT   HXT    sing N N 672 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-10-16 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8WS5 
_em_admin.last_update        2025-04-16 
_em_admin.map_release_date   2025-04-16 
_em_admin.title              'Cryo-EM structure of Cas12-1-N2/crRNA/Target DNA complex' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          12908 
_em_entity_assembly_naturalsource.organism             'unclassified sequences' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          469008 
_em_entity_assembly_recombinant.organism             'Escherichia coli BL21(DE3)' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ? ? 
MASKING                         ? 3  ? ? ? ? ? 
'CTF CORRECTION'                ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ? ? 
'MODEL FITTING'                 ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'              ? 8  ? ? ? ? ? 
OTHER                           ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ? ? 
CLASSIFICATION                  ? 12 1 ? ? ? ? 
RECONSTRUCTION                  ? 13 1 ? ? ? ? 
'VOLUME SELECTION'              ? 14 1 1 1 ? ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ? ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ? ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ? ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ? ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_ndb_struct_conf_na.entry_id 
_ndb_struct_conf_na.feature 
8WS5 'double helix'        
8WS5 'a-form double helix' 
8WS5 'b-form double helix' 
# 
loop_
_ndb_struct_na_base_pair.model_number 
_ndb_struct_na_base_pair.i_label_asym_id 
_ndb_struct_na_base_pair.i_label_comp_id 
_ndb_struct_na_base_pair.i_label_seq_id 
_ndb_struct_na_base_pair.i_symmetry 
_ndb_struct_na_base_pair.j_label_asym_id 
_ndb_struct_na_base_pair.j_label_comp_id 
_ndb_struct_na_base_pair.j_label_seq_id 
_ndb_struct_na_base_pair.j_symmetry 
_ndb_struct_na_base_pair.shear 
_ndb_struct_na_base_pair.stretch 
_ndb_struct_na_base_pair.stagger 
_ndb_struct_na_base_pair.buckle 
_ndb_struct_na_base_pair.propeller 
_ndb_struct_na_base_pair.opening 
_ndb_struct_na_base_pair.pair_number 
_ndb_struct_na_base_pair.pair_name 
_ndb_struct_na_base_pair.i_auth_asym_id 
_ndb_struct_na_base_pair.i_auth_seq_id 
_ndb_struct_na_base_pair.i_PDB_ins_code 
_ndb_struct_na_base_pair.j_auth_asym_id 
_ndb_struct_na_base_pair.j_auth_seq_id 
_ndb_struct_na_base_pair.j_PDB_ins_code 
_ndb_struct_na_base_pair.hbond_type_28 
_ndb_struct_na_base_pair.hbond_type_12 
1 B DT 14 1_555 C A  44 1_555 -1.238 3.011  0.860  -4.774  -40.889 -112.863 1  C_DT-19:A18_B C -19 ? B 18 ? 23 3 
1 B DC 16 1_555 C G  43 1_555 0.893  -0.349 1.342  -7.237  9.797   21.391   2  C_DC-17:G17_B C -17 ? B 17 ? 19 1 
1 B DA 17 1_555 C C  41 1_555 -0.631 -0.161 -1.535 -10.091 6.665   -16.296  3  C_DA-16:C15_B C -16 ? B 15 ? ?  ? 
1 B DC 19 1_555 C G  40 1_555 -0.776 0.972  0.503  -3.855  11.174  29.598   4  C_DC-14:G14_B C -14 ? B 14 ? ?  1 
1 B DA 20 1_555 C U  39 1_555 1.740  0.022  0.731  6.257   7.849   17.316   5  C_DA-13:U13_B C -13 ? B 13 ? ?  1 
1 B DG 21 1_555 C C  38 1_555 -0.112 -0.433 1.376  5.119   1.395   0.176    6  C_DG-12:C12_B C -12 ? B 12 ? 19 1 
1 B DA 23 1_555 C U  36 1_555 1.059  -6.657 -0.950 -26.038 36.327  159.141  7  C_DA-10:U10_B C -10 ? B 10 ? ?  ? 
1 B DC 24 1_555 C G  35 1_555 -2.096 4.381  0.746  -41.806 13.089  -84.503  8  C_DC-9:G9_B   C -9  ? B 9  ? ?  3 
1 B DT 26 1_555 C A  33 1_555 -0.452 0.412  -0.052 -0.926  11.173  -0.488   9  C_DT-7:A7_B   C -7  ? B 7  ? 20 1 
1 B DA 27 1_555 C U  32 1_555 0.824  -0.078 -0.768 1.708   -10.723 3.950    10 C_DA-6:U6_B   C -6  ? B 6  ? 20 1 
1 B DG 28 1_555 C C  31 1_555 0.526  0.083  -0.150 16.916  -7.026  4.091    11 C_DG-5:C5_B   C -5  ? B 5  ? 19 1 
1 B DG 29 1_555 C C  30 1_555 -0.205 -0.243 -0.530 2.218   -6.097  -1.416   12 C_DG-4:C4_B   C -4  ? B 4  ? 19 1 
1 B DG 30 1_555 C C  29 1_555 -0.207 -0.160 -0.442 -0.021  3.633   -0.480   13 C_DG-3:C3_B   C -3  ? B 3  ? 19 1 
1 B DG 31 1_555 C C  28 1_555 -0.216 -0.095 -0.390 7.645   -0.369  3.788    14 C_DG-2:C2_B   C -2  ? B 2  ? 19 1 
1 B DA 32 1_555 C U  27 1_555 -0.449 0.860  -0.764 15.878  12.611  24.772   15 C_DA-1:U1_B   C -1  ? B 1  ? ?  1 
1 B DG 33 1_555 D DC 10 1_555 -1.068 -0.411 -2.421 -26.567 -3.483  0.887    16 C_DG0:DC0_D   C 0   ? D 0  ? 19 1 
1 B DA 35 1_555 D DT 8  1_555 0.298  -0.397 0.980  2.758   -4.268  8.694    17 C_DA2:DT-2_D  C 2   ? D -2 ? 20 1 
1 B DT 36 1_555 D DA 7  1_555 -0.191 -0.158 0.568  2.913   -4.495  -1.131   18 C_DT3:DA-3_D  C 3   ? D -3 ? 20 1 
1 B DT 37 1_555 D DA 6  1_555 -0.050 -0.204 0.016  8.179   -4.859  4.989    19 C_DT4:DA-4_D  C 4   ? D -4 ? 20 1 
1 B DG 38 1_555 D DC 5  1_555 -1.752 -0.443 -0.614 1.633   -13.976 12.259   20 C_DG5:DC-5_D  C 5   ? D -5 ? 19 1 
1 B DG 39 1_555 D DC 4  1_555 -0.655 0.729  -0.032 30.258  -9.992  11.025   21 C_DG6:DC-6_D  C 6   ? D -6 ? ?  1 
1 C G  10 1_555 C A  25 1_555 0.854  1.412  -0.243 20.686  -6.101  -26.798  22 B_G-16:A-1_B  B -16 ? B -1 ? 8  1 
1 C C  11 1_555 C G  24 1_555 0.167  -0.222 0.412  1.930   -1.713  -1.792   23 B_C-15:G-2_B  B -15 ? B -2 ? 19 1 
1 C U  12 1_555 C A  23 1_555 -0.030 -0.143 0.366  1.396   0.692   0.661    24 B_U-14:A-3_B  B -14 ? B -3 ? 20 1 
1 C C  13 1_555 C G  22 1_555 0.240  -0.088 0.416  1.983   -1.256  3.545    25 B_C-13:G-4_B  B -13 ? B -4 ? 19 1 
1 C G  14 1_555 C C  21 1_555 -0.211 -0.135 -0.011 -0.856  -8.009  1.844    26 B_G-12:C-5_B  B -12 ? B -5 ? 19 1 
1 C G  15 1_555 C C  20 1_555 -0.071 -0.301 -1.220 -8.001  29.333  -3.847   27 B_G-11:C-6_B  B -11 ? B -6 ? 19 1 
1 C U  16 1_555 C G  19 1_555 1.908  -4.018 -0.636 16.265  -2.548  -98.570  28 B_U-10:G-7_B  B -10 ? B -7 ? ?  6 
# 
loop_
_ndb_struct_na_base_pair_step.model_number 
_ndb_struct_na_base_pair_step.i_label_asym_id_1 
_ndb_struct_na_base_pair_step.i_label_comp_id_1 
_ndb_struct_na_base_pair_step.i_label_seq_id_1 
_ndb_struct_na_base_pair_step.i_symmetry_1 
_ndb_struct_na_base_pair_step.j_label_asym_id_1 
_ndb_struct_na_base_pair_step.j_label_comp_id_1 
_ndb_struct_na_base_pair_step.j_label_seq_id_1 
_ndb_struct_na_base_pair_step.j_symmetry_1 
_ndb_struct_na_base_pair_step.i_label_asym_id_2 
_ndb_struct_na_base_pair_step.i_label_comp_id_2 
_ndb_struct_na_base_pair_step.i_label_seq_id_2 
_ndb_struct_na_base_pair_step.i_symmetry_2 
_ndb_struct_na_base_pair_step.j_label_asym_id_2 
_ndb_struct_na_base_pair_step.j_label_comp_id_2 
_ndb_struct_na_base_pair_step.j_label_seq_id_2 
_ndb_struct_na_base_pair_step.j_symmetry_2 
_ndb_struct_na_base_pair_step.shift 
_ndb_struct_na_base_pair_step.slide 
_ndb_struct_na_base_pair_step.rise 
_ndb_struct_na_base_pair_step.tilt 
_ndb_struct_na_base_pair_step.roll 
_ndb_struct_na_base_pair_step.twist 
_ndb_struct_na_base_pair_step.x_displacement 
_ndb_struct_na_base_pair_step.y_displacement 
_ndb_struct_na_base_pair_step.helical_rise 
_ndb_struct_na_base_pair_step.inclination 
_ndb_struct_na_base_pair_step.tip 
_ndb_struct_na_base_pair_step.helical_twist 
_ndb_struct_na_base_pair_step.step_number 
_ndb_struct_na_base_pair_step.step_name 
_ndb_struct_na_base_pair_step.i_auth_asym_id_1 
_ndb_struct_na_base_pair_step.i_auth_seq_id_1 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.j_auth_asym_id_1 
_ndb_struct_na_base_pair_step.j_auth_seq_id_1 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.i_auth_asym_id_2 
_ndb_struct_na_base_pair_step.i_auth_seq_id_2 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_2 
_ndb_struct_na_base_pair_step.j_auth_asym_id_2 
_ndb_struct_na_base_pair_step.j_auth_seq_id_2 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_2 
1 B DT 14 1_555 C A  44 1_555 B DC 16 1_555 C G  43 1_555 -0.051 -0.199 5.151  32.700  27.971  13.717   -4.312  4.805  1.446  
47.547  -55.586 45.066   1  CC_DT-19DC-17:G17A18_BB C -19 ? B 18 ? C -17 ? B 17 ? 
1 B DC 16 1_555 C G  43 1_555 B DA 17 1_555 C C  41 1_555 -1.456 -2.981 5.287  -17.654 19.225  33.715   -7.094  -0.717 3.516  
28.458  26.132  42.404   2  CC_DC-17DA-16:C15G17_BB C -17 ? B 17 ? C -16 ? B 15 ? 
1 B DA 17 1_555 C C  41 1_555 B DC 19 1_555 C G  40 1_555 -0.090 -0.992 5.537  -3.186  2.242   50.060   -1.441  -0.281 5.486  
2.645   3.759   50.201   3  CC_DA-16DC-14:G14C15_BB C -16 ? B 15 ? C -14 ? B 14 ? 
1 B DC 19 1_555 C G  40 1_555 B DA 20 1_555 C U  39 1_555 -0.649 -0.949 2.858  -0.284  4.261   36.768   -1.987  0.990  2.739  
6.727   0.448   37.007   4  CC_DC-14DA-13:U13G14_BB C -14 ? B 14 ? C -13 ? B 13 ? 
1 B DA 20 1_555 C U  39 1_555 B DG 21 1_555 C C  38 1_555 0.488  -2.160 3.528  1.829   4.012   15.419   -10.673 -0.415 2.912  
14.569  -6.640  16.033   5  CC_DA-13DG-12:C12U13_BB C -13 ? B 13 ? C -12 ? B 12 ? 
1 B DG 21 1_555 C C  38 1_555 B DA 23 1_555 C U  36 1_555 -3.512 1.653  -0.602 86.151  85.568  -176.494 -0.821  -1.762 -0.566 
-42.792 43.083  -178.285 6  CC_DG-12DA-10:U10C12_BB C -12 ? B 12 ? C -10 ? B 10 ? 
1 B DA 23 1_555 C U  36 1_555 B DC 24 1_555 C G  35 1_555 -2.370 -3.067 -1.296 137.278 -91.631 135.478  -1.676  0.975  -1.302 
-46.122 -69.098 174.350  7  CC_DA-10DC-9:G9U10_BB   C -10 ? B 10 ? C -9  ? B 9  ? 
1 B DC 24 1_555 C G  35 1_555 B DT 26 1_555 C A  33 1_555 -0.149 0.982  7.011  -13.299 11.617  21.987   -4.082  -6.680 5.971  
25.765  29.496  28.132   8  CC_DC-9DT-7:A7G9_BB     C -9  ? B 9  ? C -7  ? B 7  ? 
1 B DT 26 1_555 C A  33 1_555 B DA 27 1_555 C U  32 1_555 -0.216 -0.958 3.401  4.836   8.074   28.332   -3.537  1.423  2.946  
15.949  -9.551  29.824   9  CC_DT-7DA-6:U6A7_BB     C -7  ? B 7  ? C -6  ? B 6  ? 
1 B DA 27 1_555 C U  32 1_555 B DG 28 1_555 C C  31 1_555 0.486  -0.400 2.942  -3.827  11.468  29.867   -2.508  -1.473 2.541  
21.190  7.071   32.169   10 CC_DA-6DG-5:C5U6_BB     C -6  ? B 6  ? C -5  ? B 5  ? 
1 B DG 28 1_555 C C  31 1_555 B DG 29 1_555 C C  30 1_555 -1.150 -1.160 3.508  -4.287  7.785   33.867   -3.170  1.231  3.286  
13.087  7.207   34.980   11 CC_DG-5DG-4:C4C5_BB     C -5  ? B 5  ? C -4  ? B 4  ? 
1 B DG 29 1_555 C C  30 1_555 B DG 30 1_555 C C  29 1_555 0.516  -2.049 3.439  -1.238  8.476   26.006   -6.333  -1.383 2.625  
18.217  2.661   27.357   12 CC_DG-4DG-3:C3C4_BB     C -4  ? B 4  ? C -3  ? B 3  ? 
1 B DG 30 1_555 C C  29 1_555 B DG 31 1_555 C C  28 1_555 0.671  -1.483 3.333  2.810   4.697   33.167   -3.331  -0.702 3.144  
8.158   -4.881  33.603   13 CC_DG-3DG-2:C2C3_BB     C -3  ? B 3  ? C -2  ? B 2  ? 
1 B DG 31 1_555 C C  28 1_555 B DA 32 1_555 C U  27 1_555 2.205  -0.250 3.790  7.818   -8.886  29.779   1.564   -2.224 4.128  
-16.493 -14.511 31.995   14 CC_DG-2DA-1:U1C2_BB     C -2  ? B 2  ? C -1  ? B 1  ? 
1 B DG 33 1_555 D DC 10 1_555 B DA 35 1_555 D DT 8  1_555 1.150  0.254  6.263  -25.560 10.589  71.723   -0.389  -2.368 5.643  
8.726   21.062  76.201   15 CC_DG0DA2:DT-2DC0_DD    C 0   ? D 0  ? C 2   ? D -2 ? 
1 B DA 35 1_555 D DT 8  1_555 B DT 36 1_555 D DA 7  1_555 -0.402 -1.180 3.122  1.988   0.544   33.257   -2.143  1.014  3.074  
0.949   -3.469  33.319   16 CC_DA2DT3:DA-3DT-2_DD   C 2   ? D -2 ? C 3   ? D -3 ? 
1 B DT 36 1_555 D DA 7  1_555 B DT 37 1_555 D DA 6  1_555 0.291  -0.769 2.876  4.402   -0.095  36.582   -1.206  0.068  2.892  
-0.150  -6.982  36.837   17 CC_DT3DT4:DA-4DA-3_DD   C 3   ? D -3 ? C 4   ? D -4 ? 
1 B DT 37 1_555 D DA 6  1_555 B DG 38 1_555 D DC 5  1_555 -0.031 1.784  3.471  5.270   1.027   31.562   3.037   1.074  3.475  
1.871   -9.601  32.004   18 CC_DT4DG5:DC-5DA-4_DD   C 4   ? D -4 ? C 5   ? D -5 ? 
1 B DG 38 1_555 D DC 5  1_555 B DG 39 1_555 D DC 4  1_555 -0.707 1.661  2.621  -6.094  3.768   35.094   2.244   0.409  2.857  
6.170   9.978   35.795   19 CC_DG5DG6:DC-6DC-5_DD   C 5   ? D -5 ? C 6   ? D -6 ? 
1 C G  10 1_555 C A  25 1_555 C C  11 1_555 C G  24 1_555 1.234  -2.591 3.522  -4.685  9.372   37.937   -4.926  -2.371 2.667  
14.091  7.044   39.306   20 BB_G-16C-15:G-2A-1_BB   B -16 ? B -1 ? B -15 ? B -2 ? 
1 C C  11 1_555 C G  24 1_555 C U  12 1_555 C A  23 1_555 -0.832 -2.738 3.291  -3.877  1.210   26.018   -6.338  0.782  3.249  
2.666   8.545   26.327   21 BB_C-15U-14:A-3G-2_BB   B -15 ? B -2 ? B -14 ? B -3 ? 
1 C U  12 1_555 C A  23 1_555 C C  13 1_555 C G  22 1_555 0.589  -1.852 3.048  3.002   5.302   33.622   -3.905  -0.576 2.773  
9.073   -5.138  34.154   22 BB_U-14C-13:G-4A-3_BB   B -14 ? B -3 ? B -13 ? B -4 ? 
1 C C  13 1_555 C G  22 1_555 C G  14 1_555 C C  21 1_555 -0.115 -1.885 2.856  4.143   8.746   27.459   -5.258  0.942  2.128  
17.741  -8.403  29.084   23 BB_C-13G-12:C-5G-4_BB   B -13 ? B -4 ? B -12 ? B -5 ? 
1 C G  14 1_555 C C  21 1_555 C G  15 1_555 C C  20 1_555 -0.691 -1.782 3.993  9.093   -8.287  36.151   -1.408  2.507  4.009  
-12.903 -14.157 38.121   24 BB_G-12G-11:C-6C-5_BB   B -12 ? B -5 ? B -11 ? B -6 ? 
1 C G  15 1_555 C C  20 1_555 C U  16 1_555 C G  19 1_555 -0.833 -1.027 3.244  12.423  21.768  85.852   -1.170  0.845  2.863  
15.698  -8.959  88.749   25 BB_G-11U-10:G-7C-6_BB   B -11 ? B -6 ? B -10 ? B -7 ? 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           32188102 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    8WS5 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N     . CYS A 1 2   ? 142.257 121.508 124.418 1.00 29.77  ? 58  CYS A N     1 
ATOM 2    C CA    . CYS A 1 2   ? 140.995 120.781 124.484 1.00 29.77  ? 58  CYS A CA    1 
ATOM 3    C C     . CYS A 1 2   ? 139.839 121.589 123.893 1.00 29.77  ? 58  CYS A C     1 
ATOM 4    O O     . CYS A 1 2   ? 138.982 122.072 124.627 1.00 29.77  ? 58  CYS A O     1 
ATOM 5    C CB    . CYS A 1 2   ? 140.683 120.406 125.930 1.00 29.77  ? 58  CYS A CB    1 
ATOM 6    S SG    . CYS A 1 2   ? 141.845 119.236 126.664 1.00 29.77  ? 58  CYS A SG    1 
ATOM 7    N N     . PRO A 1 3   ? 139.816 121.727 122.566 1.00 28.19  ? 59  PRO A N     1 
ATOM 8    C CA    . PRO A 1 3   ? 138.798 122.570 121.939 1.00 28.19  ? 59  PRO A CA    1 
ATOM 9    C C     . PRO A 1 3   ? 137.412 121.980 122.109 1.00 28.19  ? 59  PRO A C     1 
ATOM 10   O O     . PRO A 1 3   ? 137.259 120.763 122.314 1.00 28.19  ? 59  PRO A O     1 
ATOM 11   C CB    . PRO A 1 3   ? 139.222 122.591 120.458 1.00 28.19  ? 59  PRO A CB    1 
ATOM 12   C CG    . PRO A 1 3   ? 140.674 122.245 120.480 1.00 28.19  ? 59  PRO A CG    1 
ATOM 13   C CD    . PRO A 1 3   ? 140.808 121.251 121.591 1.00 28.19  ? 59  PRO A CD    1 
ATOM 14   N N     . PRO A 1 4   ? 136.367 122.804 122.042 1.00 27.49  ? 60  PRO A N     1 
ATOM 15   C CA    . PRO A 1 4   ? 135.010 122.307 122.282 1.00 27.49  ? 60  PRO A CA    1 
ATOM 16   C C     . PRO A 1 4   ? 134.264 121.916 121.017 1.00 27.49  ? 60  PRO A C     1 
ATOM 17   O O     . PRO A 1 4   ? 134.761 122.095 119.901 1.00 27.49  ? 60  PRO A O     1 
ATOM 18   C CB    . PRO A 1 4   ? 134.338 123.500 122.961 1.00 27.49  ? 60  PRO A CB    1 
ATOM 19   C CG    . PRO A 1 4   ? 134.970 124.671 122.285 1.00 27.49  ? 60  PRO A CG    1 
ATOM 20   C CD    . PRO A 1 4   ? 136.384 124.269 121.902 1.00 27.49  ? 60  PRO A CD    1 
ATOM 21   N N     . ALA A 1 5   ? 133.059 121.379 121.196 1.00 27.94  ? 61  ALA A N     1 
ATOM 22   C CA    . ALA A 1 5   ? 132.162 121.062 120.096 1.00 27.94  ? 61  ALA A CA    1 
ATOM 23   C C     . ALA A 1 5   ? 130.734 121.113 120.616 1.00 27.94  ? 61  ALA A C     1 
ATOM 24   O O     . ALA A 1 5   ? 130.491 121.050 121.823 1.00 27.94  ? 61  ALA A O     1 
ATOM 25   C CB    . ALA A 1 5   ? 132.468 119.694 119.482 1.00 27.94  ? 61  ALA A CB    1 
ATOM 26   N N     . LYS A 1 6   ? 129.786 121.228 119.693 1.00 28.16  ? 62  LYS A N     1 
ATOM 27   C CA    . LYS A 1 6   ? 128.391 121.441 120.035 1.00 28.16  ? 62  LYS A CA    1 
ATOM 28   C C     . LYS A 1 6   ? 127.532 120.342 119.435 1.00 28.16  ? 62  LYS A C     1 
ATOM 29   O O     . LYS A 1 6   ? 127.785 119.882 118.319 1.00 28.16  ? 62  LYS A O     1 
ATOM 30   C CB    . LYS A 1 6   ? 127.909 122.806 119.538 1.00 28.16  ? 62  LYS A CB    1 
ATOM 31   C CG    . LYS A 1 6   ? 128.228 123.960 120.474 1.00 28.16  ? 62  LYS A CG    1 
ATOM 32   C CD    . LYS A 1 6   ? 129.665 124.431 120.336 1.00 28.16  ? 62  LYS A CD    1 
ATOM 33   C CE    . LYS A 1 6   ? 129.915 125.661 121.191 1.00 28.16  ? 62  LYS A CE    1 
ATOM 34   N NZ    . LYS A 1 6   ? 131.353 126.048 121.201 1.00 28.16  ? 62  LYS A NZ    1 
ATOM 35   N N     . VAL A 1 7   ? 126.524 119.915 120.188 1.00 24.17  ? 63  VAL A N     1 
ATOM 36   C CA    . VAL A 1 7   ? 125.531 118.957 119.723 1.00 24.17  ? 63  VAL A CA    1 
ATOM 37   C C     . VAL A 1 7   ? 124.157 119.509 120.063 1.00 24.17  ? 63  VAL A C     1 
ATOM 38   O O     . VAL A 1 7   ? 123.934 119.983 121.180 1.00 24.17  ? 63  VAL A O     1 
ATOM 39   C CB    . VAL A 1 7   ? 125.730 117.567 120.355 1.00 24.17  ? 63  VAL A CB    1 
ATOM 40   C CG1   . VAL A 1 7   ? 124.570 116.668 120.023 1.00 24.17  ? 63  VAL A CG1   1 
ATOM 41   C CG2   . VAL A 1 7   ? 127.011 116.945 119.862 1.00 24.17  ? 63  VAL A CG2   1 
ATOM 42   N N     . ASN A 1 8   ? 123.247 119.461 119.102 1.00 24.61  ? 64  ASN A N     1 
ATOM 43   C CA    . ASN A 1 8   ? 121.885 119.927 119.306 1.00 24.61  ? 64  ASN A CA    1 
ATOM 44   C C     . ASN A 1 8   ? 121.037 118.764 119.791 1.00 24.61  ? 64  ASN A C     1 
ATOM 45   O O     . ASN A 1 8   ? 120.918 117.747 119.101 1.00 24.61  ? 64  ASN A O     1 
ATOM 46   C CB    . ASN A 1 8   ? 121.313 120.514 118.019 1.00 24.61  ? 64  ASN A CB    1 
ATOM 47   C CG    . ASN A 1 8   ? 121.446 122.022 117.957 1.00 24.61  ? 64  ASN A CG    1 
ATOM 48   O OD1   . ASN A 1 8   ? 122.139 122.631 118.772 1.00 24.61  ? 64  ASN A OD1   1 
ATOM 49   N ND2   . ASN A 1 8   ? 120.779 122.635 116.986 1.00 24.61  ? 64  ASN A ND2   1 
ATOM 50   N N     . ILE A 1 9   ? 120.446 118.914 120.972 1.00 25.70  ? 65  ILE A N     1 
ATOM 51   C CA    . ILE A 1 9   ? 119.645 117.845 121.545 1.00 25.70  ? 65  ILE A CA    1 
ATOM 52   C C     . ILE A 1 9   ? 118.406 117.630 120.692 1.00 25.70  ? 65  ILE A C     1 
ATOM 53   O O     . ILE A 1 9   ? 117.663 118.575 120.394 1.00 25.70  ? 65  ILE A O     1 
ATOM 54   C CB    . ILE A 1 9   ? 119.276 118.168 122.999 1.00 25.70  ? 65  ILE A CB    1 
ATOM 55   C CG1   . ILE A 1 9   ? 120.530 118.183 123.869 1.00 25.70  ? 65  ILE A CG1   1 
ATOM 56   C CG2   . ILE A 1 9   ? 118.270 117.164 123.525 1.00 25.70  ? 65  ILE A CG2   1 
ATOM 57   C CD1   . ILE A 1 9   ? 120.512 119.238 124.941 1.00 25.70  ? 65  ILE A CD1   1 
ATOM 58   N N     . LEU A 1 10  ? 118.174 116.382 120.295 1.00 24.12  ? 66  LEU A N     1 
ATOM 59   C CA    . LEU A 1 10  ? 117.037 116.053 119.453 1.00 24.12  ? 66  LEU A CA    1 
ATOM 60   C C     . LEU A 1 10  ? 115.841 115.535 120.228 1.00 24.12  ? 66  LEU A C     1 
ATOM 61   O O     . LEU A 1 10  ? 114.718 115.984 119.978 1.00 24.12  ? 66  LEU A O     1 
ATOM 62   C CB    . LEU A 1 10  ? 117.428 115.008 118.405 1.00 24.12  ? 66  LEU A CB    1 
ATOM 63   C CG    . LEU A 1 10  ? 118.545 115.347 117.423 1.00 24.12  ? 66  LEU A CG    1 
ATOM 64   C CD1   . LEU A 1 10  ? 118.847 114.127 116.572 1.00 24.12  ? 66  LEU A CD1   1 
ATOM 65   C CD2   . LEU A 1 10  ? 118.164 116.533 116.554 1.00 24.12  ? 66  LEU A CD2   1 
ATOM 66   N N     . ALA A 1 11  ? 116.038 114.607 121.158 1.00 25.82  ? 67  ALA A N     1 
ATOM 67   C CA    . ALA A 1 11  ? 114.910 114.001 121.850 1.00 25.82  ? 67  ALA A CA    1 
ATOM 68   C C     . ALA A 1 11  ? 115.231 113.878 123.330 1.00 25.82  ? 67  ALA A C     1 
ATOM 69   O O     . ALA A 1 11  ? 116.396 113.821 123.732 1.00 25.82  ? 67  ALA A O     1 
ATOM 70   C CB    . ALA A 1 11  ? 114.558 112.634 121.260 1.00 25.82  ? 67  ALA A CB    1 
ATOM 71   N N     . GLN A 1 12  ? 114.182 113.964 124.149 1.00 28.90  ? 68  GLN A N     1 
ATOM 72   C CA    . GLN A 1 12  ? 114.339 113.882 125.601 1.00 28.90  ? 68  GLN A CA    1 
ATOM 73   C C     . GLN A 1 12  ? 112.984 113.510 126.188 1.00 28.90  ? 68  GLN A C     1 
ATOM 74   O O     . GLN A 1 12  ? 111.948 113.813 125.596 1.00 28.90  ? 68  GLN A O     1 
ATOM 75   C CB    . GLN A 1 12  ? 114.833 115.211 126.191 1.00 28.90  ? 68  GLN A CB    1 
ATOM 76   C CG    . GLN A 1 12  ? 114.366 116.466 125.462 1.00 28.90  ? 68  GLN A CG    1 
ATOM 77   C CD    . GLN A 1 12  ? 112.986 116.931 125.883 1.00 28.90  ? 68  GLN A CD    1 
ATOM 78   O OE1   . GLN A 1 12  ? 112.230 117.472 125.077 1.00 28.90  ? 68  GLN A OE1   1 
ATOM 79   N NE2   . GLN A 1 12  ? 112.649 116.718 127.146 1.00 28.90  ? 68  GLN A NE2   1 
ATOM 80   N N     . SER A 1 13  ? 112.982 112.845 127.335 1.00 28.67  ? 69  SER A N     1 
ATOM 81   C CA    . SER A 1 13  ? 111.736 112.463 127.995 1.00 28.67  ? 69  SER A CA    1 
ATOM 82   C C     . SER A 1 13  ? 111.043 113.673 128.610 1.00 28.67  ? 69  SER A C     1 
ATOM 83   O O     . SER A 1 13  ? 109.910 114.007 128.248 1.00 28.67  ? 69  SER A O     1 
ATOM 84   C CB    . SER A 1 13  ? 112.011 111.406 129.066 1.00 28.67  ? 69  SER A CB    1 
ATOM 85   O OG    . SER A 1 13  ? 112.806 111.940 130.109 1.00 28.67  ? 69  SER A OG    1 
ATOM 86   N N     . ARG A 1 14  ? 111.714 114.339 129.542 1.00 27.18  ? 70  ARG A N     1 
ATOM 87   C CA    . ARG A 1 14  ? 111.193 115.502 130.237 1.00 27.18  ? 70  ARG A CA    1 
ATOM 88   C C     . ARG A 1 14  ? 112.318 116.515 130.382 1.00 27.18  ? 70  ARG A C     1 
ATOM 89   O O     . ARG A 1 14  ? 113.493 116.134 130.402 1.00 27.18  ? 70  ARG A O     1 
ATOM 90   C CB    . ARG A 1 14  ? 110.621 115.102 131.604 1.00 27.18  ? 70  ARG A CB    1 
ATOM 91   C CG    . ARG A 1 14  ? 111.584 114.318 132.473 1.00 27.18  ? 70  ARG A CG    1 
ATOM 92   C CD    . ARG A 1 14  ? 110.829 113.503 133.511 1.00 27.18  ? 70  ARG A CD    1 
ATOM 93   N NE    . ARG A 1 14  ? 111.582 113.320 134.745 1.00 27.18  ? 70  ARG A NE    1 
ATOM 94   C CZ    . ARG A 1 14  ? 111.077 112.796 135.852 1.00 27.18  ? 70  ARG A CZ    1 
ATOM 95   N NH1   . ARG A 1 14  ? 109.824 112.377 135.908 1.00 27.18  ? 70  ARG A NH1   1 
ATOM 96   N NH2   . ARG A 1 14  ? 111.848 112.686 136.929 1.00 27.18  ? 70  ARG A NH2   1 
ATOM 97   N N     . PRO A 1 15  ? 111.991 117.807 130.485 1.00 27.83  ? 71  PRO A N     1 
ATOM 98   C CA    . PRO A 1 15  ? 113.014 118.851 130.335 1.00 27.83  ? 71  PRO A CA    1 
ATOM 99   C C     . PRO A 1 15  ? 114.192 118.673 131.281 1.00 27.83  ? 71  PRO A C     1 
ATOM 100  O O     . PRO A 1 15  ? 114.069 118.087 132.358 1.00 27.83  ? 71  PRO A O     1 
ATOM 101  C CB    . PRO A 1 15  ? 112.244 120.138 130.643 1.00 27.83  ? 71  PRO A CB    1 
ATOM 102  C CG    . PRO A 1 15  ? 110.853 119.824 130.253 1.00 27.83  ? 71  PRO A CG    1 
ATOM 103  C CD    . PRO A 1 15  ? 110.643 118.385 130.609 1.00 27.83  ? 71  PRO A CD    1 
ATOM 104  N N     . LEU A 1 16  ? 115.351 119.190 130.855 1.00 27.72  ? 72  LEU A N     1 
ATOM 105  C CA    . LEU A 1 16  ? 116.577 119.029 131.629 1.00 27.72  ? 72  LEU A CA    1 
ATOM 106  C C     . LEU A 1 16  ? 116.462 119.604 133.032 1.00 27.72  ? 72  LEU A C     1 
ATOM 107  O O     . LEU A 1 16  ? 117.033 119.038 133.970 1.00 27.72  ? 72  LEU A O     1 
ATOM 108  C CB    . LEU A 1 16  ? 117.760 119.694 130.927 1.00 27.72  ? 72  LEU A CB    1 
ATOM 109  C CG    . LEU A 1 16  ? 118.450 119.047 129.728 1.00 27.72  ? 72  LEU A CG    1 
ATOM 110  C CD1   . LEU A 1 16  ? 117.712 119.356 128.437 1.00 27.72  ? 72  LEU A CD1   1 
ATOM 111  C CD2   . LEU A 1 16  ? 119.906 119.489 129.639 1.00 27.72  ? 72  LEU A CD2   1 
ATOM 112  N N     . SER A 1 17  ? 115.741 120.711 133.200 1.00 29.88  ? 73  SER A N     1 
ATOM 113  C CA    . SER A 1 17  ? 115.674 121.386 134.488 1.00 29.88  ? 73  SER A CA    1 
ATOM 114  C C     . SER A 1 17  ? 114.983 120.561 135.562 1.00 29.88  ? 73  SER A C     1 
ATOM 115  O O     . SER A 1 17  ? 115.157 120.856 136.749 1.00 29.88  ? 73  SER A O     1 
ATOM 116  C CB    . SER A 1 17  ? 114.958 122.730 134.339 1.00 29.88  ? 73  SER A CB    1 
ATOM 117  O OG    . SER A 1 17  ? 113.779 122.597 133.564 1.00 29.88  ? 73  SER A OG    1 
ATOM 118  N N     . GLU A 1 18  ? 114.211 119.546 135.185 1.00 28.73  ? 74  GLU A N     1 
ATOM 119  C CA    . GLU A 1 18  ? 113.504 118.711 136.144 1.00 28.73  ? 74  GLU A CA    1 
ATOM 120  C C     . GLU A 1 18  ? 114.305 117.462 136.511 1.00 28.73  ? 74  GLU A C     1 
ATOM 121  O O     . GLU A 1 18  ? 113.858 116.662 137.336 1.00 28.73  ? 74  GLU A O     1 
ATOM 122  C CB    . GLU A 1 18  ? 112.114 118.373 135.575 1.00 28.73  ? 74  GLU A CB    1 
ATOM 123  C CG    . GLU A 1 18  ? 111.097 117.742 136.520 1.00 28.73  ? 74  GLU A CG    1 
ATOM 124  C CD    . GLU A 1 18  ? 111.222 116.246 136.599 1.00 28.73  ? 74  GLU A CD    1 
ATOM 125  O OE1   . GLU A 1 18  ? 111.667 115.651 135.602 1.00 28.73  ? 74  GLU A OE1   1 
ATOM 126  O OE2   . GLU A 1 18  ? 110.875 115.666 137.649 1.00 28.73  ? 74  GLU A OE2   1 
ATOM 127  N N     . TRP A 1 19  ? 115.511 117.321 135.969 1.00 27.58  ? 75  TRP A N     1 
ATOM 128  C CA    . TRP A 1 19  ? 116.369 116.191 136.295 1.00 27.58  ? 75  TRP A CA    1 
ATOM 129  C C     . TRP A 1 19  ? 116.809 116.246 137.758 1.00 27.58  ? 75  TRP A C     1 
ATOM 130  O O     . TRP A 1 19  ? 116.995 117.333 138.312 1.00 27.58  ? 75  TRP A O     1 
ATOM 131  C CB    . TRP A 1 19  ? 117.604 116.196 135.396 1.00 27.58  ? 75  TRP A CB    1 
ATOM 132  C CG    . TRP A 1 19  ? 117.417 115.496 134.099 1.00 27.58  ? 75  TRP A CG    1 
ATOM 133  C CD1   . TRP A 1 19  ? 116.243 115.260 133.462 1.00 27.58  ? 75  TRP A CD1   1 
ATOM 134  C CD2   . TRP A 1 19  ? 118.444 114.968 133.258 1.00 27.58  ? 75  TRP A CD2   1 
ATOM 135  N NE1   . TRP A 1 19  ? 116.470 114.598 132.286 1.00 27.58  ? 75  TRP A NE1   1 
ATOM 136  C CE2   . TRP A 1 19  ? 117.817 114.410 132.137 1.00 27.58  ? 75  TRP A CE2   1 
ATOM 137  C CE3   . TRP A 1 19  ? 119.837 114.907 133.352 1.00 27.58  ? 75  TRP A CE3   1 
ATOM 138  C CZ2   . TRP A 1 19  ? 118.528 113.799 131.115 1.00 27.58  ? 75  TRP A CZ2   1 
ATOM 139  C CZ3   . TRP A 1 19  ? 120.541 114.301 132.336 1.00 27.58  ? 75  TRP A CZ3   1 
ATOM 140  C CH2   . TRP A 1 19  ? 119.887 113.755 131.233 1.00 27.58  ? 75  TRP A CH2   1 
ATOM 141  N N     . PRO A 1 20  ? 116.984 115.095 138.408 1.00 27.57  ? 76  PRO A N     1 
ATOM 142  C CA    . PRO A 1 20  ? 117.520 115.107 139.778 1.00 27.57  ? 76  PRO A CA    1 
ATOM 143  C C     . PRO A 1 20  ? 118.888 115.747 139.892 1.00 27.57  ? 76  PRO A C     1 
ATOM 144  O O     . PRO A 1 20  ? 119.169 116.398 140.906 1.00 27.57  ? 76  PRO A O     1 
ATOM 145  C CB    . PRO A 1 20  ? 117.554 113.619 140.146 1.00 27.57  ? 76  PRO A CB    1 
ATOM 146  C CG    . PRO A 1 20  ? 116.462 113.012 139.313 1.00 27.57  ? 76  PRO A CG    1 
ATOM 147  C CD    . PRO A 1 20  ? 116.502 113.761 138.011 1.00 27.57  ? 76  PRO A CD    1 
ATOM 148  N N     . ILE A 1 21  ? 119.739 115.579 138.890 1.00 27.81  ? 77  ILE A N     1 
ATOM 149  C CA    . ILE A 1 21  ? 121.050 116.216 138.923 1.00 27.81  ? 77  ILE A CA    1 
ATOM 150  C C     . ILE A 1 21  ? 120.927 117.748 138.970 1.00 27.81  ? 77  ILE A C     1 
ATOM 151  O O     . ILE A 1 21  ? 121.559 118.387 139.810 1.00 27.81  ? 77  ILE A O     1 
ATOM 152  C CB    . ILE A 1 21  ? 121.961 115.712 137.779 1.00 27.81  ? 77  ILE A CB    1 
ATOM 153  C CG1   . ILE A 1 21  ? 123.196 116.605 137.606 1.00 27.81  ? 77  ILE A CG1   1 
ATOM 154  C CG2   . ILE A 1 21  ? 121.176 115.584 136.488 1.00 27.81  ? 77  ILE A CG2   1 
ATOM 155  C CD1   . ILE A 1 21  ? 124.256 116.404 138.668 1.00 27.81  ? 77  ILE A CD1   1 
ATOM 156  N N     . ASN A 1 22  ? 120.096 118.332 138.108 1.00 30.14  ? 78  ASN A N     1 
ATOM 157  C CA    . ASN A 1 22  ? 119.915 119.780 138.110 1.00 30.14  ? 78  ASN A CA    1 
ATOM 158  C C     . ASN A 1 22  ? 119.311 120.263 139.423 1.00 30.14  ? 78  ASN A C     1 
ATOM 159  O O     . ASN A 1 22  ? 119.765 121.264 139.988 1.00 30.14  ? 78  ASN A O     1 
ATOM 160  C CB    . ASN A 1 22  ? 119.038 120.195 136.926 1.00 30.14  ? 78  ASN A CB    1 
ATOM 161  C CG    . ASN A 1 22  ? 119.148 121.673 136.600 1.00 30.14  ? 78  ASN A CG    1 
ATOM 162  O OD1   . ASN A 1 22  ? 118.146 122.343 136.355 1.00 30.14  ? 78  ASN A OD1   1 
ATOM 163  N ND2   . ASN A 1 22  ? 120.373 122.188 136.594 1.00 30.14  ? 78  ASN A ND2   1 
ATOM 164  N N     . LEU A 1 23  ? 118.301 119.550 139.927 1.00 28.78  ? 79  LEU A N     1 
ATOM 165  C CA    . LEU A 1 23  ? 117.645 119.953 141.167 1.00 28.78  ? 79  LEU A CA    1 
ATOM 166  C C     . LEU A 1 23  ? 118.612 119.919 142.343 1.00 28.78  ? 79  LEU A C     1 
ATOM 167  O O     . LEU A 1 23  ? 118.676 120.865 143.136 1.00 28.78  ? 79  LEU A O     1 
ATOM 168  C CB    . LEU A 1 23  ? 116.444 119.050 141.434 1.00 28.78  ? 79  LEU A CB    1 
ATOM 169  C CG    . LEU A 1 23  ? 115.225 119.324 140.560 1.00 28.78  ? 79  LEU A CG    1 
ATOM 170  C CD1   . LEU A 1 23  ? 114.058 118.446 140.981 1.00 28.78  ? 79  LEU A CD1   1 
ATOM 171  C CD2   . LEU A 1 23  ? 114.856 120.794 140.626 1.00 28.78  ? 79  LEU A CD2   1 
ATOM 172  N N     . VAL A 1 24  ? 119.375 118.834 142.473 1.00 27.82  ? 80  VAL A N     1 
ATOM 173  C CA    . VAL A 1 24  ? 120.280 118.711 143.607 1.00 27.82  ? 80  VAL A CA    1 
ATOM 174  C C     . VAL A 1 24  ? 121.412 119.721 143.497 1.00 27.82  ? 80  VAL A C     1 
ATOM 175  O O     . VAL A 1 24  ? 121.838 120.302 144.504 1.00 27.82  ? 80  VAL A O     1 
ATOM 176  C CB    . VAL A 1 24  ? 120.805 117.270 143.725 1.00 27.82  ? 80  VAL A CB    1 
ATOM 177  C CG1   . VAL A 1 24  ? 121.894 117.195 144.756 1.00 27.82  ? 80  VAL A CG1   1 
ATOM 178  C CG2   . VAL A 1 24  ? 119.670 116.321 144.083 1.00 27.82  ? 80  VAL A CG2   1 
ATOM 179  N N     . SER A 1 25  ? 121.892 119.965 142.283 1.00 27.80  ? 81  SER A N     1 
ATOM 180  C CA    . SER A 1 25  ? 122.925 120.978 142.094 1.00 27.80  ? 81  SER A CA    1 
ATOM 181  C C     . SER A 1 25  ? 122.398 122.316 142.558 1.00 27.80  ? 81  SER A C     1 
ATOM 182  O O     . SER A 1 25  ? 123.027 122.982 143.371 1.00 27.80  ? 81  SER A O     1 
ATOM 183  C CB    . SER A 1 25  ? 123.326 121.074 140.623 1.00 27.80  ? 81  SER A CB    1 
ATOM 184  O OG    . SER A 1 25  ? 124.236 122.139 140.411 1.00 27.80  ? 81  SER A OG    1 
ATOM 185  N N     . LYS A 1 26  ? 121.234 122.712 142.051 1.00 30.21  ? 82  LYS A N     1 
ATOM 186  C CA    . LYS A 1 26  ? 120.683 124.020 142.399 1.00 30.21  ? 82  LYS A CA    1 
ATOM 187  C C     . LYS A 1 26  ? 120.422 124.140 143.898 1.00 30.21  ? 82  LYS A C     1 
ATOM 188  O O     . LYS A 1 26  ? 120.642 125.203 144.469 1.00 30.21  ? 82  LYS A O     1 
ATOM 189  C CB    . LYS A 1 26  ? 119.439 124.356 141.561 1.00 30.21  ? 82  LYS A CB    1 
ATOM 190  C CG    . LYS A 1 26  ? 118.101 124.034 142.204 1.00 30.21  ? 82  LYS A CG    1 
ATOM 191  C CD    . LYS A 1 26  ? 116.942 124.519 141.354 1.00 30.21  ? 82  LYS A CD    1 
ATOM 192  C CE    . LYS A 1 26  ? 115.633 124.416 142.118 1.00 30.21  ? 82  LYS A CE    1 
ATOM 193  N NZ    . LYS A 1 26  ? 115.671 125.210 143.377 1.00 30.21  ? 82  LYS A NZ    1 
ATOM 194  N N     . GLY A 1 27  ? 119.979 123.062 144.543 1.00 28.62  ? 83  GLY A N     1 
ATOM 195  C CA    . GLY A 1 27  ? 119.790 123.100 145.985 1.00 28.62  ? 83  GLY A CA    1 
ATOM 196  C C     . GLY A 1 27  ? 121.092 123.286 146.739 1.00 28.62  ? 83  GLY A C     1 
ATOM 197  O O     . GLY A 1 27  ? 121.182 124.106 147.658 1.00 28.62  ? 83  GLY A O     1 
ATOM 198  N N     . VAL A 1 28  ? 122.118 122.519 146.367 1.00 27.95  ? 84  VAL A N     1 
ATOM 199  C CA    . VAL A 1 28  ? 123.424 122.657 146.999 1.00 27.95  ? 84  VAL A CA    1 
ATOM 200  C C     . VAL A 1 28  ? 123.935 124.078 146.851 1.00 27.95  ? 84  VAL A C     1 
ATOM 201  O O     . VAL A 1 28  ? 124.465 124.660 147.807 1.00 27.95  ? 84  VAL A O     1 
ATOM 202  C CB    . VAL A 1 28  ? 124.418 121.639 146.407 1.00 27.95  ? 84  VAL A CB    1 
ATOM 203  C CG1   . VAL A 1 28  ? 125.828 121.964 146.828 1.00 27.95  ? 84  VAL A CG1   1 
ATOM 204  C CG2   . VAL A 1 28  ? 124.058 120.233 146.836 1.00 27.95  ? 84  VAL A CG2   1 
ATOM 205  N N     . GLN A 1 29  ? 123.779 124.666 145.666 1.00 29.02  ? 85  GLN A N     1 
ATOM 206  C CA    . GLN A 1 29  ? 124.262 126.024 145.461 1.00 29.02  ? 85  GLN A CA    1 
ATOM 207  C C     . GLN A 1 29  ? 123.442 127.049 146.232 1.00 29.02  ? 85  GLN A C     1 
ATOM 208  O O     . GLN A 1 29  ? 124.015 127.964 146.828 1.00 29.02  ? 85  GLN A O     1 
ATOM 209  C CB    . GLN A 1 29  ? 124.281 126.352 143.971 1.00 29.02  ? 85  GLN A CB    1 
ATOM 210  C CG    . GLN A 1 29  ? 125.098 125.368 143.164 1.00 29.02  ? 85  GLN A CG    1 
ATOM 211  C CD    . GLN A 1 29  ? 125.400 125.854 141.775 1.00 29.02  ? 85  GLN A CD    1 
ATOM 212  O OE1   . GLN A 1 29  ? 125.442 127.052 141.520 1.00 29.02  ? 85  GLN A OE1   1 
ATOM 213  N NE2   . GLN A 1 29  ? 125.614 124.922 140.861 1.00 29.02  ? 85  GLN A NE2   1 
ATOM 214  N N     . GLU A 1 30  ? 122.117 126.917 146.251 1.00 31.00  ? 86  GLU A N     1 
ATOM 215  C CA    . GLU A 1 30  ? 121.291 127.841 147.014 1.00 31.00  ? 86  GLU A CA    1 
ATOM 216  C C     . GLU A 1 30  ? 121.538 127.744 148.509 1.00 31.00  ? 86  GLU A C     1 
ATOM 217  O O     . GLU A 1 30  ? 121.325 128.732 149.219 1.00 31.00  ? 86  GLU A O     1 
ATOM 218  C CB    . GLU A 1 30  ? 119.810 127.595 146.724 1.00 31.00  ? 86  GLU A CB    1 
ATOM 219  C CG    . GLU A 1 30  ? 119.344 128.111 145.373 1.00 31.00  ? 86  GLU A CG    1 
ATOM 220  C CD    . GLU A 1 30  ? 117.862 127.888 145.147 1.00 31.00  ? 86  GLU A CD    1 
ATOM 221  O OE1   . GLU A 1 30  ? 117.239 127.159 145.948 1.00 31.00  ? 86  GLU A OE1   1 
ATOM 222  O OE2   . GLU A 1 30  ? 117.318 128.442 144.169 1.00 31.00  ? 86  GLU A OE2   1 
ATOM 223  N N     . TYR A 1 31  ? 121.976 126.589 149.006 1.00 29.25  ? 87  TYR A N     1 
ATOM 224  C CA    . TYR A 1 31  ? 122.318 126.461 150.415 1.00 29.25  ? 87  TYR A CA    1 
ATOM 225  C C     . TYR A 1 31  ? 123.698 127.026 150.719 1.00 29.25  ? 87  TYR A C     1 
ATOM 226  O O     . TYR A 1 31  ? 123.845 127.840 151.635 1.00 29.25  ? 87  TYR A O     1 
ATOM 227  C CB    . TYR A 1 31  ? 122.241 124.993 150.856 1.00 29.25  ? 87  TYR A CB    1 
ATOM 228  C CG    . TYR A 1 31  ? 122.762 124.740 152.258 1.00 29.25  ? 87  TYR A CG    1 
ATOM 229  C CD1   . TYR A 1 31  ? 124.098 124.437 152.481 1.00 29.25  ? 87  TYR A CD1   1 
ATOM 230  C CD2   . TYR A 1 31  ? 121.918 124.803 153.351 1.00 29.25  ? 87  TYR A CD2   1 
ATOM 231  C CE1   . TYR A 1 31  ? 124.578 124.216 153.752 1.00 29.25  ? 87  TYR A CE1   1 
ATOM 232  C CE2   . TYR A 1 31  ? 122.388 124.578 154.628 1.00 29.25  ? 87  TYR A CE2   1 
ATOM 233  C CZ    . TYR A 1 31  ? 123.719 124.283 154.822 1.00 29.25  ? 87  TYR A CZ    1 
ATOM 234  O OH    . TYR A 1 31  ? 124.194 124.056 156.093 1.00 29.25  ? 87  TYR A OH    1 
ATOM 235  N N     . VAL A 1 32  ? 124.717 126.607 149.968 1.00 26.29  ? 88  VAL A N     1 
ATOM 236  C CA    . VAL A 1 32  ? 126.074 127.069 150.234 1.00 26.29  ? 88  VAL A CA    1 
ATOM 237  C C     . VAL A 1 32  ? 126.177 128.570 150.029 1.00 26.29  ? 88  VAL A C     1 
ATOM 238  O O     . VAL A 1 32  ? 126.788 129.281 150.835 1.00 26.29  ? 88  VAL A O     1 
ATOM 239  C CB    . VAL A 1 32  ? 127.077 126.309 149.349 1.00 26.29  ? 88  VAL A CB    1 
ATOM 240  C CG1   . VAL A 1 32  ? 128.478 126.855 149.535 1.00 26.29  ? 88  VAL A CG1   1 
ATOM 241  C CG2   . VAL A 1 32  ? 127.040 124.823 149.671 1.00 26.29  ? 88  VAL A CG2   1 
ATOM 242  N N     . TYR A 1 33  ? 125.585 129.077 148.956 1.00 28.49  ? 89  TYR A N     1 
ATOM 243  C CA    . TYR A 1 33  ? 125.727 130.480 148.586 1.00 28.49  ? 89  TYR A CA    1 
ATOM 244  C C     . TYR A 1 33  ? 125.016 131.342 149.614 1.00 28.49  ? 89  TYR A C     1 
ATOM 245  O O     . TYR A 1 33  ? 123.786 131.398 149.672 1.00 28.49  ? 89  TYR A O     1 
ATOM 246  C CB    . TYR A 1 33  ? 125.198 130.713 147.178 1.00 28.49  ? 89  TYR A CB    1 
ATOM 247  C CG    . TYR A 1 33  ? 126.174 130.262 146.126 1.00 28.49  ? 89  TYR A CG    1 
ATOM 248  C CD1   . TYR A 1 33  ? 127.531 130.500 146.274 1.00 28.49  ? 89  TYR A CD1   1 
ATOM 249  C CD2   . TYR A 1 33  ? 125.748 129.582 145.001 1.00 28.49  ? 89  TYR A CD2   1 
ATOM 250  C CE1   . TYR A 1 33  ? 128.428 130.085 145.326 1.00 28.49  ? 89  TYR A CE1   1 
ATOM 251  C CE2   . TYR A 1 33  ? 126.638 129.166 144.051 1.00 28.49  ? 89  TYR A CE2   1 
ATOM 252  C CZ    . TYR A 1 33  ? 127.976 129.418 144.216 1.00 28.49  ? 89  TYR A CZ    1 
ATOM 253  O OH    . TYR A 1 33  ? 128.867 129.002 143.258 1.00 28.49  ? 89  TYR A OH    1 
ATOM 254  N N     . GLY A 1 34  ? 125.816 132.005 150.435 1.00 27.84  ? 90  GLY A N     1 
ATOM 255  C CA    . GLY A 1 34  ? 125.364 132.786 151.559 1.00 27.84  ? 90  GLY A CA    1 
ATOM 256  C C     . GLY A 1 34  ? 125.560 131.968 152.813 1.00 27.84  ? 90  GLY A C     1 
ATOM 257  O O     . GLY A 1 34  ? 124.676 131.212 153.223 1.00 27.84  ? 90  GLY A O     1 
ATOM 258  N N     . LEU A 1 35  ? 126.707 132.162 153.453 1.00 25.76  ? 91  LEU A N     1 
ATOM 259  C CA    . LEU A 1 35  ? 127.097 131.402 154.632 1.00 25.76  ? 91  LEU A CA    1 
ATOM 260  C C     . LEU A 1 35  ? 128.251 132.147 155.270 1.00 25.76  ? 91  LEU A C     1 
ATOM 261  O O     . LEU A 1 35  ? 129.237 132.447 154.595 1.00 25.76  ? 91  LEU A O     1 
ATOM 262  C CB    . LEU A 1 35  ? 127.514 129.955 154.297 1.00 25.76  ? 91  LEU A CB    1 
ATOM 263  C CG    . LEU A 1 35  ? 126.454 128.847 154.185 1.00 25.76  ? 91  LEU A CG    1 
ATOM 264  C CD1   . LEU A 1 35  ? 127.066 127.521 153.781 1.00 25.76  ? 91  LEU A CD1   1 
ATOM 265  C CD2   . LEU A 1 35  ? 125.697 128.699 155.489 1.00 25.76  ? 91  LEU A CD2   1 
ATOM 266  N N     . THR A 1 36  ? 128.118 132.454 156.551 1.00 27.59  ? 92  THR A N     1 
ATOM 267  C CA    . THR A 1 36  ? 129.166 133.176 157.244 1.00 27.59  ? 92  THR A CA    1 
ATOM 268  C C     . THR A 1 36  ? 130.468 132.391 157.165 1.00 27.59  ? 92  THR A C     1 
ATOM 269  O O     . THR A 1 36  ? 130.472 131.158 157.119 1.00 27.59  ? 92  THR A O     1 
ATOM 270  C CB    . THR A 1 36  ? 128.760 133.418 158.694 1.00 27.59  ? 92  THR A CB    1 
ATOM 271  O OG1   . THR A 1 36  ? 127.405 133.880 158.727 1.00 27.59  ? 92  THR A OG1   1 
ATOM 272  C CG2   . THR A 1 36  ? 129.656 134.468 159.337 1.00 27.59  ? 92  THR A CG2   1 
ATOM 273  N N     . ALA A 1 37  ? 131.586 133.121 157.136 1.00 26.98  ? 93  ALA A N     1 
ATOM 274  C CA    . ALA A 1 37  ? 132.880 132.495 156.892 1.00 26.98  ? 93  ALA A CA    1 
ATOM 275  C C     . ALA A 1 37  ? 133.192 131.392 157.892 1.00 26.98  ? 93  ALA A C     1 
ATOM 276  O O     . ALA A 1 37  ? 133.956 130.478 157.568 1.00 26.98  ? 93  ALA A O     1 
ATOM 277  C CB    . ALA A 1 37  ? 133.987 133.548 156.918 1.00 26.98  ? 93  ALA A CB    1 
ATOM 278  N N     . ALA A 1 38  ? 132.621 131.449 159.088 1.00 27.31  ? 94  ALA A N     1 
ATOM 279  C CA    . ALA A 1 38  ? 132.787 130.396 160.076 1.00 27.31  ? 94  ALA A CA    1 
ATOM 280  C C     . ALA A 1 38  ? 131.722 129.307 159.975 1.00 27.31  ? 94  ALA A C     1 
ATOM 281  O O     . ALA A 1 38  ? 131.826 128.297 160.678 1.00 27.31  ? 94  ALA A O     1 
ATOM 282  C CB    . ALA A 1 38  ? 132.788 130.994 161.483 1.00 27.31  ? 94  ALA A CB    1 
ATOM 283  N N     . GLU A 1 39  ? 130.742 129.476 159.100 1.00 28.61  ? 95  GLU A N     1 
ATOM 284  C CA    . GLU A 1 39  ? 129.749 128.430 158.901 1.00 28.61  ? 95  GLU A CA    1 
ATOM 285  C C     . GLU A 1 39  ? 130.213 127.471 157.804 1.00 28.61  ? 95  GLU A C     1 
ATOM 286  O O     . GLU A 1 39  ? 130.022 126.261 157.922 1.00 28.61  ? 95  GLU A O     1 
ATOM 287  C CB    . GLU A 1 39  ? 128.380 129.025 158.566 1.00 28.61  ? 95  GLU A CB    1 
ATOM 288  C CG    . GLU A 1 39  ? 127.229 128.045 158.718 1.00 28.61  ? 95  GLU A CG    1 
ATOM 289  C CD    . GLU A 1 39  ? 126.994 127.628 160.157 1.00 28.61  ? 95  GLU A CD    1 
ATOM 290  O OE1   . GLU A 1 39  ? 127.212 128.456 161.067 1.00 28.61  ? 95  GLU A OE1   1 
ATOM 291  O OE2   . GLU A 1 39  ? 126.576 126.472 160.378 1.00 28.61  ? 95  GLU A OE2   1 
ATOM 292  N N     . ARG A 1 40  ? 130.874 128.003 156.775 1.00 28.45  ? 96  ARG A N     1 
ATOM 293  C CA    . ARG A 1 40  ? 131.373 127.166 155.676 1.00 28.45  ? 96  ARG A CA    1 
ATOM 294  C C     . ARG A 1 40  ? 132.514 126.248 156.101 1.00 28.45  ? 96  ARG A C     1 
ATOM 295  O O     . ARG A 1 40  ? 132.799 125.280 155.413 1.00 28.45  ? 96  ARG A O     1 
ATOM 296  C CB    . ARG A 1 40  ? 131.779 128.019 154.468 1.00 28.45  ? 96  ARG A CB    1 
ATOM 297  C CG    . ARG A 1 40  ? 133.058 128.820 154.646 1.00 28.45  ? 96  ARG A CG    1 
ATOM 298  C CD    . ARG A 1 40  ? 133.563 129.322 153.303 1.00 28.45  ? 96  ARG A CD    1 
ATOM 299  N NE    . ARG A 1 40  ? 134.909 129.881 153.388 1.00 28.45  ? 96  ARG A NE    1 
ATOM 300  C CZ    . ARG A 1 40  ? 135.605 130.308 152.339 1.00 28.45  ? 96  ARG A CZ    1 
ATOM 301  N NH1   . ARG A 1 40  ? 135.084 130.237 151.121 1.00 28.45  ? 96  ARG A NH1   1 
ATOM 302  N NH2   . ARG A 1 40  ? 136.824 130.802 152.505 1.00 28.45  ? 96  ARG A NH2   1 
ATOM 303  N N     . GLU A 1 41  ? 133.197 126.558 157.198 1.00 29.28  ? 97  GLU A N     1 
ATOM 304  C CA    . GLU A 1 41  ? 134.228 125.676 157.733 1.00 29.28  ? 97  GLU A CA    1 
ATOM 305  C C     . GLU A 1 41  ? 133.617 124.418 158.327 1.00 29.28  ? 97  GLU A C     1 
ATOM 306  O O     . GLU A 1 41  ? 134.076 123.302 158.059 1.00 29.28  ? 97  GLU A O     1 
ATOM 307  C CB    . GLU A 1 41  ? 135.049 126.418 158.783 1.00 29.28  ? 97  GLU A CB    1 
ATOM 308  C CG    . GLU A 1 41  ? 135.682 127.699 158.274 1.00 29.28  ? 97  GLU A CG    1 
ATOM 309  C CD    . GLU A 1 41  ? 136.721 127.450 157.200 1.00 29.28  ? 97  GLU A CD    1 
ATOM 310  O OE1   . GLU A 1 41  ? 137.454 126.444 157.302 1.00 29.28  ? 97  GLU A OE1   1 
ATOM 311  O OE2   . GLU A 1 41  ? 136.805 128.261 156.254 1.00 29.28  ? 97  GLU A OE2   1 
ATOM 312  N N     . ALA A 1 42  ? 132.578 124.578 159.144 1.00 30.58  ? 98  ALA A N     1 
ATOM 313  C CA    . ALA A 1 42  ? 131.909 123.420 159.723 1.00 30.58  ? 98  ALA A CA    1 
ATOM 314  C C     . ALA A 1 42  ? 131.232 122.588 158.645 1.00 30.58  ? 98  ALA A C     1 
ATOM 315  O O     . ALA A 1 42  ? 131.299 121.354 158.661 1.00 30.58  ? 98  ALA A O     1 
ATOM 316  C CB    . ALA A 1 42  ? 130.895 123.872 160.774 1.00 30.58  ? 98  ALA A CB    1 
ATOM 317  N N     . ASN A 1 43  ? 130.576 123.250 157.692 1.00 28.65  ? 99  ASN A N     1 
ATOM 318  C CA    . ASN A 1 43  ? 129.836 122.531 156.666 1.00 28.65  ? 99  ASN A CA    1 
ATOM 319  C C     . ASN A 1 43  ? 130.683 122.215 155.445 1.00 28.65  ? 99  ASN A C     1 
ATOM 320  O O     . ASN A 1 43  ? 130.213 121.502 154.553 1.00 28.65  ? 99  ASN A O     1 
ATOM 321  C CB    . ASN A 1 43  ? 128.596 123.328 156.261 1.00 28.65  ? 99  ASN A CB    1 
ATOM 322  C CG    . ASN A 1 43  ? 127.613 123.488 157.403 1.00 28.65  ? 99  ASN A CG    1 
ATOM 323  O OD1   . ASN A 1 43  ? 126.558 122.862 157.422 1.00 28.65  ? 99  ASN A OD1   1 
ATOM 324  N ND2   . ASN A 1 43  ? 127.960 124.330 158.368 1.00 28.65  ? 99  ASN A ND2   1 
ATOM 325  N N     . GLY A 1 44  ? 131.909 122.722 155.380 1.00 30.95  ? 100 GLY A N     1 
ATOM 326  C CA    . GLY A 1 44  ? 132.798 122.374 154.292 1.00 30.95  ? 100 GLY A CA    1 
ATOM 327  C C     . GLY A 1 44  ? 133.632 121.144 154.587 1.00 30.95  ? 100 GLY A C     1 
ATOM 328  O O     . GLY A 1 44  ? 134.818 121.094 154.248 1.00 30.95  ? 100 GLY A O     1 
ATOM 329  N N     . THR A 1 48  ? 135.438 112.531 149.319 1.00 28.75  ? 104 THR A N     1 
ATOM 330  C CA    . THR A 1 48  ? 134.974 111.658 148.247 1.00 28.75  ? 104 THR A CA    1 
ATOM 331  C C     . THR A 1 48  ? 134.644 110.316 148.888 1.00 28.75  ? 104 THR A C     1 
ATOM 332  O O     . THR A 1 48  ? 135.530 109.471 149.050 1.00 28.75  ? 104 THR A O     1 
ATOM 333  C CB    . THR A 1 48  ? 136.026 111.510 147.157 1.00 28.75  ? 104 THR A CB    1 
ATOM 334  O OG1   . THR A 1 48  ? 136.355 112.799 146.624 1.00 28.75  ? 104 THR A OG1   1 
ATOM 335  C CG2   . THR A 1 48  ? 135.523 110.597 146.051 1.00 28.75  ? 104 THR A CG2   1 
ATOM 336  N N     . SER A 1 49  ? 133.382 110.127 149.244 1.00 29.07  ? 105 SER A N     1 
ATOM 337  C CA    . SER A 1 49  ? 132.992 108.897 149.907 1.00 29.07  ? 105 SER A CA    1 
ATOM 338  C C     . SER A 1 49  ? 131.485 108.755 149.839 1.00 29.07  ? 105 SER A C     1 
ATOM 339  O O     . SER A 1 49  ? 130.759 109.751 149.794 1.00 29.07  ? 105 SER A O     1 
ATOM 340  C CB    . SER A 1 49  ? 133.458 108.876 151.366 1.00 29.07  ? 105 SER A CB    1 
ATOM 341  O OG    . SER A 1 49  ? 132.812 107.845 152.090 1.00 29.07  ? 105 SER A OG    1 
ATOM 342  N N     . ARG A 1 50  ? 131.025 107.507 149.827 1.00 32.23  ? 106 ARG A N     1 
ATOM 343  C CA    . ARG A 1 50  ? 129.605 107.262 150.025 1.00 32.23  ? 106 ARG A CA    1 
ATOM 344  C C     . ARG A 1 50  ? 129.176 107.684 151.423 1.00 32.23  ? 106 ARG A C     1 
ATOM 345  O O     . ARG A 1 50  ? 128.104 108.272 151.600 1.00 32.23  ? 106 ARG A O     1 
ATOM 346  C CB    . ARG A 1 50  ? 129.282 105.791 149.783 1.00 32.23  ? 106 ARG A CB    1 
ATOM 347  C CG    . ARG A 1 50  ? 127.797 105.545 149.597 1.00 32.23  ? 106 ARG A CG    1 
ATOM 348  C CD    . ARG A 1 50  ? 127.495 104.169 149.032 1.00 32.23  ? 106 ARG A CD    1 
ATOM 349  N NE    . ARG A 1 50  ? 126.085 104.044 148.682 1.00 32.23  ? 106 ARG A NE    1 
ATOM 350  C CZ    . ARG A 1 50  ? 125.541 102.970 148.127 1.00 32.23  ? 106 ARG A CZ    1 
ATOM 351  N NH1   . ARG A 1 50  ? 126.262 101.897 147.846 1.00 32.23  ? 106 ARG A NH1   1 
ATOM 352  N NH2   . ARG A 1 50  ? 124.241 102.973 147.846 1.00 32.23  ? 106 ARG A NH2   1 
ATOM 353  N N     . LYS A 1 51  ? 130.012 107.412 152.429 1.00 31.62  ? 107 LYS A N     1 
ATOM 354  C CA    . LYS A 1 51  ? 129.654 107.738 153.807 1.00 31.62  ? 107 LYS A CA    1 
ATOM 355  C C     . LYS A 1 51  ? 129.764 109.234 154.085 1.00 31.62  ? 107 LYS A C     1 
ATOM 356  O O     . LYS A 1 51  ? 128.917 109.799 154.787 1.00 31.62  ? 107 LYS A O     1 
ATOM 357  C CB    . LYS A 1 51  ? 130.531 106.951 154.777 1.00 31.62  ? 107 LYS A CB    1 
ATOM 358  C CG    . LYS A 1 51  ? 129.996 105.568 155.103 1.00 31.62  ? 107 LYS A CG    1 
ATOM 359  C CD    . LYS A 1 51  ? 128.595 105.646 155.687 1.00 31.62  ? 107 LYS A CD    1 
ATOM 360  C CE    . LYS A 1 51  ? 128.123 104.288 156.179 1.00 31.62  ? 107 LYS A CE    1 
ATOM 361  N NZ    . LYS A 1 51  ? 128.231 103.246 155.120 1.00 31.62  ? 107 LYS A NZ    1 
ATOM 362  N N     . SER A 1 52  ? 130.801 109.895 153.561 1.00 28.04  ? 108 SER A N     1 
ATOM 363  C CA    . SER A 1 52  ? 130.961 111.324 153.824 1.00 28.04  ? 108 SER A CA    1 
ATOM 364  C C     . SER A 1 52  ? 129.815 112.123 153.215 1.00 28.04  ? 108 SER A C     1 
ATOM 365  O O     . SER A 1 52  ? 129.185 112.944 153.896 1.00 28.04  ? 108 SER A O     1 
ATOM 366  C CB    . SER A 1 52  ? 132.300 111.823 153.285 1.00 28.04  ? 108 SER A CB    1 
ATOM 367  O OG    . SER A 1 52  ? 132.201 112.140 151.913 1.00 28.04  ? 108 SER A OG    1 
ATOM 368  N N     . LEU A 1 53  ? 129.527 111.893 151.939 1.00 27.86  ? 109 LEU A N     1 
ATOM 369  C CA    . LEU A 1 53  ? 128.398 112.548 151.290 1.00 27.86  ? 109 LEU A CA    1 
ATOM 370  C C     . LEU A 1 53  ? 127.123 111.734 151.474 1.00 27.86  ? 109 LEU A C     1 
ATOM 371  O O     . LEU A 1 53  ? 126.344 111.497 150.552 1.00 27.86  ? 109 LEU A O     1 
ATOM 372  C CB    . LEU A 1 53  ? 128.720 112.757 149.818 1.00 27.86  ? 109 LEU A CB    1 
ATOM 373  C CG    . LEU A 1 53  ? 129.959 113.638 149.746 1.00 27.86  ? 109 LEU A CG    1 
ATOM 374  C CD1   . LEU A 1 53  ? 130.454 113.788 148.335 1.00 27.86  ? 109 LEU A CD1   1 
ATOM 375  C CD2   . LEU A 1 53  ? 129.681 114.994 150.370 1.00 27.86  ? 109 LEU A CD2   1 
ATOM 376  N N     . ASP A 1 54  ? 126.926 111.306 152.720 1.00 27.76  ? 110 ASP A N     1 
ATOM 377  C CA    . ASP A 1 54  ? 125.646 110.820 153.212 1.00 27.76  ? 110 ASP A CA    1 
ATOM 378  C C     . ASP A 1 54  ? 125.411 111.331 154.623 1.00 27.76  ? 110 ASP A C     1 
ATOM 379  O O     . ASP A 1 54  ? 124.288 111.223 155.130 1.00 27.76  ? 110 ASP A O     1 
ATOM 380  C CB    . ASP A 1 54  ? 125.566 109.293 153.177 1.00 27.76  ? 110 ASP A CB    1 
ATOM 381  C CG    . ASP A 1 54  ? 125.118 108.766 151.829 1.00 27.76  ? 110 ASP A CG    1 
ATOM 382  O OD1   . ASP A 1 54  ? 124.397 109.495 151.116 1.00 27.76  ? 110 ASP A OD1   1 
ATOM 383  O OD2   . ASP A 1 54  ? 125.467 107.620 151.485 1.00 27.76  ? 110 ASP A OD2   1 
ATOM 384  N N     . ARG A 1 55  ? 126.440 111.876 155.267 1.00 27.92  ? 111 ARG A N     1 
ATOM 385  C CA    . ARG A 1 55  ? 126.280 112.725 156.435 1.00 27.92  ? 111 ARG A CA    1 
ATOM 386  C C     . ARG A 1 55  ? 126.311 114.199 156.086 1.00 27.92  ? 111 ARG A C     1 
ATOM 387  O O     . ARG A 1 55  ? 125.732 115.002 156.814 1.00 27.92  ? 111 ARG A O     1 
ATOM 388  C CB    . ARG A 1 55  ? 127.380 112.451 157.468 1.00 27.92  ? 111 ARG A CB    1 
ATOM 389  C CG    . ARG A 1 55  ? 128.788 112.696 156.946 1.00 27.92  ? 111 ARG A CG    1 
ATOM 390  C CD    . ARG A 1 55  ? 129.743 113.024 158.066 1.00 27.92  ? 111 ARG A CD    1 
ATOM 391  N NE    . ARG A 1 55  ? 131.071 113.341 157.562 1.00 27.92  ? 111 ARG A NE    1 
ATOM 392  C CZ    . ARG A 1 55  ? 132.134 112.565 157.720 1.00 27.92  ? 111 ARG A CZ    1 
ATOM 393  N NH1   . ARG A 1 55  ? 132.059 111.413 158.366 1.00 27.92  ? 111 ARG A NH1   1 
ATOM 394  N NH2   . ARG A 1 55  ? 133.302 112.955 157.218 1.00 27.92  ? 111 ARG A NH2   1 
ATOM 395  N N     . TRP A 1 56  ? 126.990 114.573 154.998 1.00 24.93  ? 112 TRP A N     1 
ATOM 396  C CA    . TRP A 1 56  ? 126.976 115.967 154.569 1.00 24.93  ? 112 TRP A CA    1 
ATOM 397  C C     . TRP A 1 56  ? 125.572 116.381 154.170 1.00 24.93  ? 112 TRP A C     1 
ATOM 398  O O     . TRP A 1 56  ? 125.167 117.529 154.379 1.00 24.93  ? 112 TRP A O     1 
ATOM 399  C CB    . TRP A 1 56  ? 127.943 116.160 153.403 1.00 24.93  ? 112 TRP A CB    1 
ATOM 400  C CG    . TRP A 1 56  ? 128.410 117.558 153.200 1.00 24.93  ? 112 TRP A CG    1 
ATOM 401  C CD1   . TRP A 1 56  ? 129.587 118.083 153.617 1.00 24.93  ? 112 TRP A CD1   1 
ATOM 402  C CD2   . TRP A 1 56  ? 127.712 118.616 152.532 1.00 24.93  ? 112 TRP A CD2   1 
ATOM 403  N NE1   . TRP A 1 56  ? 129.678 119.398 153.250 1.00 24.93  ? 112 TRP A NE1   1 
ATOM 404  C CE2   . TRP A 1 56  ? 128.538 119.753 152.582 1.00 24.93  ? 112 TRP A CE2   1 
ATOM 405  C CE3   . TRP A 1 56  ? 126.473 118.711 151.896 1.00 24.93  ? 112 TRP A CE3   1 
ATOM 406  C CZ2   . TRP A 1 56  ? 128.169 120.967 152.024 1.00 24.93  ? 112 TRP A CZ2   1 
ATOM 407  C CZ3   . TRP A 1 56  ? 126.104 119.918 151.343 1.00 24.93  ? 112 TRP A CZ3   1 
ATOM 408  C CH2   . TRP A 1 56  ? 126.950 121.032 151.409 1.00 24.93  ? 112 TRP A CH2   1 
ATOM 409  N N     . PHE A 1 57  ? 124.812 115.447 153.606 1.00 24.25  ? 113 PHE A N     1 
ATOM 410  C CA    . PHE A 1 57  ? 123.431 115.657 153.207 1.00 24.25  ? 113 PHE A CA    1 
ATOM 411  C C     . PHE A 1 57  ? 122.452 115.513 154.367 1.00 24.25  ? 113 PHE A C     1 
ATOM 412  O O     . PHE A 1 57  ? 121.239 115.502 154.137 1.00 24.25  ? 113 PHE A O     1 
ATOM 413  C CB    . PHE A 1 57  ? 123.065 114.688 152.083 1.00 24.25  ? 113 PHE A CB    1 
ATOM 414  C CG    . PHE A 1 57  ? 123.302 115.245 150.715 1.00 24.25  ? 113 PHE A CG    1 
ATOM 415  C CD1   . PHE A 1 57  ? 124.547 115.713 150.355 1.00 24.25  ? 113 PHE A CD1   1 
ATOM 416  C CD2   . PHE A 1 57  ? 122.276 115.318 149.797 1.00 24.25  ? 113 PHE A CD2   1 
ATOM 417  C CE1   . PHE A 1 57  ? 124.767 116.233 149.112 1.00 24.25  ? 113 PHE A CE1   1 
ATOM 418  C CE2   . PHE A 1 57  ? 122.494 115.839 148.543 1.00 24.25  ? 113 PHE A CE2   1 
ATOM 419  C CZ    . PHE A 1 57  ? 123.743 116.299 148.203 1.00 24.25  ? 113 PHE A CZ    1 
ATOM 420  N N     . ALA A 1 58  ? 122.949 115.393 155.590 1.00 27.57  ? 114 ALA A N     1 
ATOM 421  C CA    . ALA A 1 58  ? 122.133 115.411 156.799 1.00 27.57  ? 114 ALA A CA    1 
ATOM 422  C C     . ALA A 1 58  ? 122.523 116.536 157.745 1.00 27.57  ? 114 ALA A C     1 
ATOM 423  O O     . ALA A 1 58  ? 121.644 117.157 158.348 1.00 27.57  ? 114 ALA A O     1 
ATOM 424  C CB    . ALA A 1 58  ? 122.230 114.061 157.525 1.00 27.57  ? 114 ALA A CB    1 
ATOM 425  N N     . ARG A 1 59  ? 123.822 116.808 157.894 1.00 27.10  ? 115 ARG A N     1 
ATOM 426  C CA    . ARG A 1 59  ? 124.268 117.986 158.630 1.00 27.10  ? 115 ARG A CA    1 
ATOM 427  C C     . ARG A 1 59  ? 123.742 119.257 157.979 1.00 27.10  ? 115 ARG A C     1 
ATOM 428  O O     . ARG A 1 59  ? 123.131 120.104 158.640 1.00 27.10  ? 115 ARG A O     1 
ATOM 429  C CB    . ARG A 1 59  ? 125.792 118.013 158.693 1.00 27.10  ? 115 ARG A CB    1 
ATOM 430  C CG    . ARG A 1 59  ? 126.355 119.309 159.213 1.00 27.10  ? 115 ARG A CG    1 
ATOM 431  C CD    . ARG A 1 59  ? 127.830 119.186 159.485 1.00 27.10  ? 115 ARG A CD    1 
ATOM 432  N NE    . ARG A 1 59  ? 128.527 118.633 158.334 1.00 27.10  ? 115 ARG A NE    1 
ATOM 433  C CZ    . ARG A 1 59  ? 129.796 118.254 158.336 1.00 27.10  ? 115 ARG A CZ    1 
ATOM 434  N NH1   . ARG A 1 59  ? 130.543 118.348 159.423 1.00 27.10  ? 115 ARG A NH1   1 
ATOM 435  N NH2   . ARG A 1 59  ? 130.329 117.772 157.218 1.00 27.10  ? 115 ARG A NH2   1 
ATOM 436  N N     . THR A 1 60  ? 123.972 119.403 156.679 1.00 25.51  ? 116 THR A N     1 
ATOM 437  C CA    . THR A 1 60  ? 123.345 120.464 155.913 1.00 25.51  ? 116 THR A CA    1 
ATOM 438  C C     . THR A 1 60  ? 121.933 120.053 155.523 1.00 25.51  ? 116 THR A C     1 
ATOM 439  O O     . THR A 1 60  ? 121.664 118.890 155.220 1.00 25.51  ? 116 THR A O     1 
ATOM 440  C CB    . THR A 1 60  ? 124.152 120.773 154.659 1.00 25.51  ? 116 THR A CB    1 
ATOM 441  O OG1   . THR A 1 60  ? 124.197 119.605 153.832 1.00 25.51  ? 116 THR A OG1   1 
ATOM 442  C CG2   . THR A 1 60  ? 125.564 121.156 155.027 1.00 25.51  ? 116 THR A CG2   1 
ATOM 443  N N     . GLY A 1 61  ? 121.026 121.021 155.534 1.00 26.91  ? 117 GLY A N     1 
ATOM 444  C CA    . GLY A 1 61  ? 119.668 120.765 155.102 1.00 26.91  ? 117 GLY A CA    1 
ATOM 445  C C     . GLY A 1 61  ? 119.509 120.845 153.599 1.00 26.91  ? 117 GLY A C     1 
ATOM 446  O O     . GLY A 1 61  ? 118.638 121.561 153.097 1.00 26.91  ? 117 GLY A O     1 
ATOM 447  N N     . VAL A 1 62  ? 120.346 120.120 152.867 1.00 24.98  ? 118 VAL A N     1 
ATOM 448  C CA    . VAL A 1 62  ? 120.243 120.058 151.414 1.00 24.98  ? 118 VAL A CA    1 
ATOM 449  C C     . VAL A 1 62  ? 119.643 118.708 151.049 1.00 24.98  ? 118 VAL A C     1 
ATOM 450  O O     . VAL A 1 62  ? 120.343 117.686 151.104 1.00 24.98  ? 118 VAL A O     1 
ATOM 451  C CB    . VAL A 1 62  ? 121.608 120.245 150.739 1.00 24.98  ? 118 VAL A CB    1 
ATOM 452  C CG1   . VAL A 1 62  ? 121.440 120.299 149.245 1.00 24.98  ? 118 VAL A CG1   1 
ATOM 453  C CG2   . VAL A 1 62  ? 122.288 121.487 151.247 1.00 24.98  ? 118 VAL A CG2   1 
ATOM 454  N N     . PRO A 1 63  ? 118.367 118.648 150.682 1.00 27.18  ? 119 PRO A N     1 
ATOM 455  C CA    . PRO A 1 63  ? 117.765 117.358 150.345 1.00 27.18  ? 119 PRO A CA    1 
ATOM 456  C C     . PRO A 1 63  ? 118.325 116.807 149.047 1.00 27.18  ? 119 PRO A C     1 
ATOM 457  O O     . PRO A 1 63  ? 118.649 117.546 148.116 1.00 27.18  ? 119 PRO A O     1 
ATOM 458  C CB    . PRO A 1 63  ? 116.276 117.691 150.207 1.00 27.18  ? 119 PRO A CB    1 
ATOM 459  C CG    . PRO A 1 63  ? 116.265 119.124 149.796 1.00 27.18  ? 119 PRO A CG    1 
ATOM 460  C CD    . PRO A 1 63  ? 117.412 119.759 150.530 1.00 27.18  ? 119 PRO A CD    1 
ATOM 461  N N     . THR A 1 64  ? 118.437 115.486 148.995 1.00 30.22  ? 120 THR A N     1 
ATOM 462  C CA    . THR A 1 64  ? 118.761 114.773 147.770 1.00 30.22  ? 120 THR A CA    1 
ATOM 463  C C     . THR A 1 64  ? 117.468 114.225 147.189 1.00 30.22  ? 120 THR A C     1 
ATOM 464  O O     . THR A 1 64  ? 116.609 113.731 147.928 1.00 30.22  ? 120 THR A O     1 
ATOM 465  C CB    . THR A 1 64  ? 119.771 113.650 148.023 1.00 30.22  ? 120 THR A CB    1 
ATOM 466  O OG1   . THR A 1 64  ? 120.115 113.021 146.782 1.00 30.22  ? 120 THR A OG1   1 
ATOM 467  C CG2   . THR A 1 64  ? 119.223 112.610 148.996 1.00 30.22  ? 120 THR A CG2   1 
ATOM 468  N N     . HIS A 1 65  ? 117.308 114.349 145.877 1.00 32.71  ? 121 HIS A N     1 
ATOM 469  C CA    . HIS A 1 65  ? 116.056 113.980 145.239 1.00 32.71  ? 121 HIS A CA    1 
ATOM 470  C C     . HIS A 1 65  ? 116.065 112.549 144.724 1.00 32.71  ? 121 HIS A C     1 
ATOM 471  O O     . HIS A 1 65  ? 115.259 112.208 143.852 1.00 32.71  ? 121 HIS A O     1 
ATOM 472  C CB    . HIS A 1 65  ? 115.735 114.957 144.110 1.00 32.71  ? 121 HIS A CB    1 
ATOM 473  C CG    . HIS A 1 65  ? 114.277 115.037 143.785 1.00 32.71  ? 121 HIS A CG    1 
ATOM 474  N ND1   . HIS A 1 65  ? 113.363 115.640 144.621 1.00 32.71  ? 121 HIS A ND1   1 
ATOM 475  C CD2   . HIS A 1 65  ? 113.574 114.593 142.716 1.00 32.71  ? 121 HIS A CD2   1 
ATOM 476  C CE1   . HIS A 1 65  ? 112.159 115.563 144.082 1.00 32.71  ? 121 HIS A CE1   1 
ATOM 477  N NE2   . HIS A 1 65  ? 112.260 114.932 142.925 1.00 32.71  ? 121 HIS A NE2   1 
ATOM 478  N N     . GLY A 1 66  ? 116.955 111.709 145.241 1.00 30.19  ? 122 GLY A N     1 
ATOM 479  C CA    . GLY A 1 66  ? 117.057 110.341 144.783 1.00 30.19  ? 122 GLY A CA    1 
ATOM 480  C C     . GLY A 1 66  ? 118.337 110.148 144.007 1.00 30.19  ? 122 GLY A C     1 
ATOM 481  O O     . GLY A 1 66  ? 118.425 109.296 143.118 1.00 30.19  ? 122 GLY A O     1 
ATOM 482  N N     . TYR A 1 67  ? 119.341 110.946 144.343 1.00 27.23  ? 123 TYR A N     1 
ATOM 483  C CA    . TYR A 1 67  ? 120.572 111.040 143.574 1.00 27.23  ? 123 TYR A CA    1 
ATOM 484  C C     . TYR A 1 67  ? 121.749 110.906 144.531 1.00 27.23  ? 123 TYR A C     1 
ATOM 485  O O     . TYR A 1 67  ? 122.222 111.898 145.087 1.00 27.23  ? 123 TYR A O     1 
ATOM 486  C CB    . TYR A 1 67  ? 120.614 112.352 142.829 1.00 27.23  ? 123 TYR A CB    1 
ATOM 487  C CG    . TYR A 1 67  ? 121.754 112.452 141.860 1.00 27.23  ? 123 TYR A CG    1 
ATOM 488  C CD1   . TYR A 1 67  ? 121.678 111.840 140.623 1.00 27.23  ? 123 TYR A CD1   1 
ATOM 489  C CD2   . TYR A 1 67  ? 122.903 113.158 142.177 1.00 27.23  ? 123 TYR A CD2   1 
ATOM 490  C CE1   . TYR A 1 67  ? 122.706 111.920 139.731 1.00 27.23  ? 123 TYR A CE1   1 
ATOM 491  C CE2   . TYR A 1 67  ? 123.945 113.243 141.286 1.00 27.23  ? 123 TYR A CE2   1 
ATOM 492  C CZ    . TYR A 1 67  ? 123.835 112.617 140.065 1.00 27.23  ? 123 TYR A CZ    1 
ATOM 493  O OH    . TYR A 1 67  ? 124.851 112.689 139.153 1.00 27.23  ? 123 TYR A OH    1 
ATOM 494  N N     . THR A 1 68  ? 122.218 109.679 144.727 1.00 26.78  ? 124 THR A N     1 
ATOM 495  C CA    . THR A 1 68  ? 123.392 109.403 145.550 1.00 26.78  ? 124 THR A CA    1 
ATOM 496  C C     . THR A 1 68  ? 124.436 108.798 144.626 1.00 26.78  ? 124 THR A C     1 
ATOM 497  O O     . THR A 1 68  ? 124.503 107.579 144.456 1.00 26.78  ? 124 THR A O     1 
ATOM 498  C CB    . THR A 1 68  ? 123.070 108.472 146.715 1.00 26.78  ? 124 THR A CB    1 
ATOM 499  O OG1   . THR A 1 68  ? 122.048 109.059 147.531 1.00 26.78  ? 124 THR A OG1   1 
ATOM 500  C CG2   . THR A 1 68  ? 124.314 108.240 147.563 1.00 26.78  ? 124 THR A CG2   1 
ATOM 501  N N     . THR A 1 69  ? 125.225 109.660 143.999 1.00 25.15  ? 125 THR A N     1 
ATOM 502  C CA    . THR A 1 69  ? 126.268 109.196 143.101 1.00 25.15  ? 125 THR A CA    1 
ATOM 503  C C     . THR A 1 69  ? 127.506 109.995 143.436 1.00 25.15  ? 125 THR A C     1 
ATOM 504  O O     . THR A 1 69  ? 127.468 111.200 143.394 1.00 25.15  ? 125 THR A O     1 
ATOM 505  C CB    . THR A 1 69  ? 125.896 109.454 141.633 1.00 25.15  ? 125 THR A CB    1 
ATOM 506  O OG1   . THR A 1 69  ? 124.665 108.790 141.322 1.00 25.15  ? 125 THR A OG1   1 
ATOM 507  C CG2   . THR A 1 69  ? 126.985 108.943 140.720 1.00 25.15  ? 125 THR A CG2   1 
ATOM 508  N N     . VAL A 1 70  ? 128.594 109.334 143.792 1.00 25.72  ? 126 VAL A N     1 
ATOM 509  C CA    . VAL A 1 70  ? 129.841 110.008 144.129 1.00 25.72  ? 126 VAL A CA    1 
ATOM 510  C C     . VAL A 1 70  ? 130.334 110.830 142.948 1.00 25.72  ? 126 VAL A C     1 
ATOM 511  O O     . VAL A 1 70  ? 130.653 112.009 143.100 1.00 25.72  ? 126 VAL A O     1 
ATOM 512  C CB    . VAL A 1 70  ? 130.920 108.996 144.554 1.00 25.72  ? 126 VAL A CB    1 
ATOM 513  C CG1   . VAL A 1 70  ? 132.116 109.719 145.147 1.00 25.72  ? 126 VAL A CG1   1 
ATOM 514  C CG2   . VAL A 1 70  ? 130.347 108.020 145.570 1.00 25.72  ? 126 VAL A CG2   1 
ATOM 515  N N     . GLN A 1 71  ? 130.381 110.221 141.766 1.00 26.63  ? 127 GLN A N     1 
ATOM 516  C CA    . GLN A 1 71  ? 130.785 110.971 140.586 1.00 26.63  ? 127 GLN A CA    1 
ATOM 517  C C     . GLN A 1 71  ? 129.782 112.064 140.251 1.00 26.63  ? 127 GLN A C     1 
ATOM 518  O O     . GLN A 1 71  ? 130.126 113.010 139.536 1.00 26.63  ? 127 GLN A O     1 
ATOM 519  C CB    . GLN A 1 71  ? 130.961 110.018 139.403 1.00 26.63  ? 127 GLN A CB    1 
ATOM 520  C CG    . GLN A 1 71  ? 131.755 108.769 139.753 1.00 26.63  ? 127 GLN A CG    1 
ATOM 521  C CD    . GLN A 1 71  ? 132.614 108.266 138.618 1.00 26.63  ? 127 GLN A CD    1 
ATOM 522  O OE1   . GLN A 1 71  ? 133.380 109.019 138.022 1.00 26.63  ? 127 GLN A OE1   1 
ATOM 523  N NE2   . GLN A 1 71  ? 132.498 106.980 138.319 1.00 26.63  ? 127 GLN A NE2   1 
ATOM 524  N N     . GLY A 1 72  ? 128.561 111.959 140.763 1.00 25.53  ? 128 GLY A N     1 
ATOM 525  C CA    . GLY A 1 72  ? 127.528 112.934 140.494 1.00 25.53  ? 128 GLY A CA    1 
ATOM 526  C C     . GLY A 1 72  ? 127.358 113.929 141.616 1.00 25.53  ? 128 GLY A C     1 
ATOM 527  O O     . GLY A 1 72  ? 126.962 115.073 141.378 1.00 25.53  ? 128 GLY A O     1 
ATOM 528  N N     . LEU A 1 73  ? 127.775 113.603 142.831 1.00 22.18  ? 129 LEU A N     1 
ATOM 529  C CA    . LEU A 1 73  ? 127.703 114.579 143.921 1.00 22.18  ? 129 LEU A CA    1 
ATOM 530  C C     . LEU A 1 73  ? 128.965 115.414 144.111 1.00 22.18  ? 129 LEU A C     1 
ATOM 531  O O     . LEU A 1 73  ? 128.875 116.631 144.265 1.00 22.18  ? 129 LEU A O     1 
ATOM 532  C CB    . LEU A 1 73  ? 127.326 113.901 145.243 1.00 22.18  ? 129 LEU A CB    1 
ATOM 533  C CG    . LEU A 1 73  ? 125.898 113.361 145.342 1.00 22.18  ? 129 LEU A CG    1 
ATOM 534  C CD1   . LEU A 1 73  ? 125.673 112.670 146.678 1.00 22.18  ? 129 LEU A CD1   1 
ATOM 535  C CD2   . LEU A 1 73  ? 124.890 114.478 145.131 1.00 22.18  ? 129 LEU A CD2   1 
ATOM 536  N N     . ASN A 1 74  ? 130.135 114.783 144.090 1.00 23.14  ? 130 ASN A N     1 
ATOM 537  C CA    . ASN A 1 74  ? 131.381 115.507 144.367 1.00 23.14  ? 130 ASN A CA    1 
ATOM 538  C C     . ASN A 1 74  ? 131.589 116.697 143.434 1.00 23.14  ? 130 ASN A C     1 
ATOM 539  O O     . ASN A 1 74  ? 132.037 117.747 143.877 1.00 23.14  ? 130 ASN A O     1 
ATOM 540  C CB    . ASN A 1 74  ? 132.583 114.563 144.298 1.00 23.14  ? 130 ASN A CB    1 
ATOM 541  C CG    . ASN A 1 74  ? 133.810 115.129 144.988 1.00 23.14  ? 130 ASN A CG    1 
ATOM 542  O OD1   . ASN A 1 74  ? 133.708 116.021 145.830 1.00 23.14  ? 130 ASN A OD1   1 
ATOM 543  N ND2   . ASN A 1 74  ? 134.977 114.603 144.640 1.00 23.14  ? 130 ASN A ND2   1 
ATOM 544  N N     . LEU A 1 75  ? 131.278 116.537 142.151 1.00 24.99  ? 131 LEU A N     1 
ATOM 545  C CA    . LEU A 1 75  ? 131.416 117.622 141.179 1.00 24.99  ? 131 LEU A CA    1 
ATOM 546  C C     . LEU A 1 75  ? 130.784 118.924 141.663 1.00 24.99  ? 131 LEU A C     1 
ATOM 547  O O     . LEU A 1 75  ? 131.487 119.919 141.825 1.00 24.99  ? 131 LEU A O     1 
ATOM 548  C CB    . LEU A 1 75  ? 130.775 117.157 139.873 1.00 24.99  ? 131 LEU A CB    1 
ATOM 549  C CG    . LEU A 1 75  ? 131.346 115.993 139.080 1.00 24.99  ? 131 LEU A CG    1 
ATOM 550  C CD1   . LEU A 1 75  ? 130.423 115.667 137.917 1.00 24.99  ? 131 LEU A CD1   1 
ATOM 551  C CD2   . LEU A 1 75  ? 132.744 116.347 138.600 1.00 24.99  ? 131 LEU A CD2   1 
ATOM 552  N N     . ILE A 1 76  ? 129.480 118.912 141.905 1.00 23.71  ? 132 ILE A N     1 
ATOM 553  C CA    . ILE A 1 76  ? 128.800 120.105 142.377 1.00 23.71  ? 132 ILE A CA    1 
ATOM 554  C C     . ILE A 1 76  ? 129.523 120.656 143.584 1.00 23.71  ? 132 ILE A C     1 
ATOM 555  O O     . ILE A 1 76  ? 129.771 121.853 143.664 1.00 23.71  ? 132 ILE A O     1 
ATOM 556  C CB    . ILE A 1 76  ? 127.366 119.774 142.820 1.00 23.71  ? 132 ILE A CB    1 
ATOM 557  C CG1   . ILE A 1 76  ? 126.716 118.791 141.844 1.00 23.71  ? 132 ILE A CG1   1 
ATOM 558  C CG2   . ILE A 1 76  ? 126.549 121.047 142.971 1.00 23.71  ? 132 ILE A CG2   1 
ATOM 559  C CD1   . ILE A 1 76  ? 125.466 118.135 142.386 1.00 23.71  ? 132 ILE A CD1   1 
ATOM 560  N N     . LEU A 1 77  ? 129.906 119.784 144.506 1.00 23.19  ? 133 LEU A N     1 
ATOM 561  C CA    . LEU A 1 77  ? 130.509 120.235 145.749 1.00 23.19  ? 133 LEU A CA    1 
ATOM 562  C C     . LEU A 1 77  ? 131.919 120.748 145.558 1.00 23.19  ? 133 LEU A C     1 
ATOM 563  O O     . LEU A 1 77  ? 132.412 121.487 146.414 1.00 23.19  ? 133 LEU A O     1 
ATOM 564  C CB    . LEU A 1 77  ? 130.506 119.113 146.789 1.00 23.19  ? 133 LEU A CB    1 
ATOM 565  C CG    . LEU A 1 77  ? 129.275 119.020 147.700 1.00 23.19  ? 133 LEU A CG    1 
ATOM 566  C CD1   . LEU A 1 77  ? 128.072 118.408 147.006 1.00 23.19  ? 133 LEU A CD1   1 
ATOM 567  C CD2   . LEU A 1 77  ? 129.606 118.261 148.966 1.00 23.19  ? 133 LEU A CD2   1 
ATOM 568  N N     . ARG A 1 78  ? 132.549 120.375 144.452 1.00 26.25  ? 134 ARG A N     1 
ATOM 569  C CA    . ARG A 1 78  ? 133.889 120.849 144.158 1.00 26.25  ? 134 ARG A CA    1 
ATOM 570  C C     . ARG A 1 78  ? 133.769 122.227 143.524 1.00 26.25  ? 134 ARG A C     1 
ATOM 571  O O     . ARG A 1 78  ? 134.523 123.137 143.866 1.00 26.25  ? 134 ARG A O     1 
ATOM 572  C CB    . ARG A 1 78  ? 134.598 119.878 143.214 1.00 26.25  ? 134 ARG A CB    1 
ATOM 573  C CG    . ARG A 1 78  ? 136.090 119.731 143.459 1.00 26.25  ? 134 ARG A CG    1 
ATOM 574  C CD    . ARG A 1 78  ? 136.896 120.731 142.648 1.00 26.25  ? 134 ARG A CD    1 
ATOM 575  N NE    . ARG A 1 78  ? 136.574 120.653 141.228 1.00 26.25  ? 134 ARG A NE    1 
ATOM 576  C CZ    . ARG A 1 78  ? 137.241 121.297 140.277 1.00 26.25  ? 134 ARG A CZ    1 
ATOM 577  N NH1   . ARG A 1 78  ? 138.276 122.063 140.594 1.00 26.25  ? 134 ARG A NH1   1 
ATOM 578  N NH2   . ARG A 1 78  ? 136.879 121.172 139.010 1.00 26.25  ? 134 ARG A NH2   1 
ATOM 579  N N     . HIS A 1 79  ? 132.813 122.388 142.610 1.00 27.33  ? 135 HIS A N     1 
ATOM 580  C CA    . HIS A 1 79  ? 132.669 123.673 141.934 1.00 27.33  ? 135 HIS A CA    1 
ATOM 581  C C     . HIS A 1 79  ? 132.118 124.740 142.871 1.00 27.33  ? 135 HIS A C     1 
ATOM 582  O O     . HIS A 1 79  ? 132.619 125.868 142.895 1.00 27.33  ? 135 HIS A O     1 
ATOM 583  C CB    . HIS A 1 79  ? 131.768 123.543 140.706 1.00 27.33  ? 135 HIS A CB    1 
ATOM 584  C CG    . HIS A 1 79  ? 132.152 122.432 139.781 1.00 27.33  ? 135 HIS A CG    1 
ATOM 585  N ND1   . HIS A 1 79  ? 133.432 121.930 139.713 1.00 27.33  ? 135 HIS A ND1   1 
ATOM 586  C CD2   . HIS A 1 79  ? 131.432 121.751 138.860 1.00 27.33  ? 135 HIS A CD2   1 
ATOM 587  C CE1   . HIS A 1 79  ? 133.480 120.976 138.803 1.00 27.33  ? 135 HIS A CE1   1 
ATOM 588  N NE2   . HIS A 1 79  ? 132.281 120.851 138.267 1.00 27.33  ? 135 HIS A NE2   1 
ATOM 589  N N     . THR A 1 80  ? 131.073 124.408 143.633 1.00 25.24  ? 136 THR A N     1 
ATOM 590  C CA    . THR A 1 80  ? 130.424 125.398 144.485 1.00 25.24  ? 136 THR A CA    1 
ATOM 591  C C     . THR A 1 80  ? 131.423 126.044 145.429 1.00 25.24  ? 136 THR A C     1 
ATOM 592  O O     . THR A 1 80  ? 131.531 127.271 145.501 1.00 25.24  ? 136 THR A O     1 
ATOM 593  C CB    . THR A 1 80  ? 129.294 124.739 145.281 1.00 25.24  ? 136 THR A CB    1 
ATOM 594  O OG1   . THR A 1 80  ? 128.435 124.006 144.402 1.00 25.24  ? 136 THR A OG1   1 
ATOM 595  C CG2   . THR A 1 80  ? 128.484 125.774 146.016 1.00 25.24  ? 136 THR A CG2   1 
ATOM 596  N N     . PHE A 1 81  ? 132.174 125.224 146.151 1.00 26.27  ? 137 PHE A N     1 
ATOM 597  C CA    . PHE A 1 81  ? 133.055 125.735 147.185 1.00 26.27  ? 137 PHE A CA    1 
ATOM 598  C C     . PHE A 1 81  ? 134.307 126.372 146.610 1.00 26.27  ? 137 PHE A C     1 
ATOM 599  O O     . PHE A 1 81  ? 134.972 127.141 147.312 1.00 26.27  ? 137 PHE A O     1 
ATOM 600  C CB    . PHE A 1 81  ? 133.409 124.608 148.155 1.00 26.27  ? 137 PHE A CB    1 
ATOM 601  C CG    . PHE A 1 81  ? 132.267 124.207 149.046 1.00 26.27  ? 137 PHE A CG    1 
ATOM 602  C CD1   . PHE A 1 81  ? 131.234 123.431 148.559 1.00 26.27  ? 137 PHE A CD1   1 
ATOM 603  C CD2   . PHE A 1 81  ? 132.216 124.619 150.361 1.00 26.27  ? 137 PHE A CD2   1 
ATOM 604  C CE1   . PHE A 1 81  ? 130.185 123.074 149.363 1.00 26.27  ? 137 PHE A CE1   1 
ATOM 605  C CE2   . PHE A 1 81  ? 131.166 124.258 151.166 1.00 26.27  ? 137 PHE A CE2   1 
ATOM 606  C CZ    . PHE A 1 81  ? 130.149 123.482 150.662 1.00 26.27  ? 137 PHE A CZ    1 
ATOM 607  N N     . ASN A 1 82  ? 134.644 126.069 145.355 1.00 29.86  ? 138 ASN A N     1 
ATOM 608  C CA    . ASN A 1 82  ? 135.715 126.797 144.686 1.00 29.86  ? 138 ASN A CA    1 
ATOM 609  C C     . ASN A 1 82  ? 135.236 128.165 144.210 1.00 29.86  ? 138 ASN A C     1 
ATOM 610  O O     . ASN A 1 82  ? 135.997 129.135 144.251 1.00 29.86  ? 138 ASN A O     1 
ATOM 611  C CB    . ASN A 1 82  ? 136.266 125.976 143.523 1.00 29.86  ? 138 ASN A CB    1 
ATOM 612  C CG    . ASN A 1 82  ? 137.772 126.111 143.377 1.00 29.86  ? 138 ASN A CG    1 
ATOM 613  O OD1   . ASN A 1 82  ? 138.403 126.918 144.058 1.00 29.86  ? 138 ASN A OD1   1 
ATOM 614  N ND2   . ASN A 1 82  ? 138.355 125.318 142.486 1.00 29.86  ? 138 ASN A ND2   1 
ATOM 615  N N     . ARG A 1 83  ? 133.982 128.267 143.759 1.00 29.90  ? 139 ARG A N     1 
ATOM 616  C CA    . ARG A 1 83  ? 133.417 129.577 143.437 1.00 29.90  ? 139 ARG A CA    1 
ATOM 617  C C     . ARG A 1 83  ? 133.301 130.445 144.682 1.00 29.90  ? 139 ARG A C     1 
ATOM 618  O O     . ARG A 1 83  ? 133.604 131.643 144.650 1.00 29.90  ? 139 ARG A O     1 
ATOM 619  C CB    . ARG A 1 83  ? 132.043 129.444 142.776 1.00 29.90  ? 139 ARG A CB    1 
ATOM 620  C CG    . ARG A 1 83  ? 132.055 129.431 141.259 1.00 29.90  ? 139 ARG A CG    1 
ATOM 621  C CD    . ARG A 1 83  ? 132.091 128.030 140.696 1.00 29.90  ? 139 ARG A CD    1 
ATOM 622  N NE    . ARG A 1 83  ? 130.876 127.293 141.024 1.00 29.90  ? 139 ARG A NE    1 
ATOM 623  C CZ    . ARG A 1 83  ? 129.735 127.403 140.359 1.00 29.90  ? 139 ARG A CZ    1 
ATOM 624  N NH1   . ARG A 1 83  ? 129.610 128.228 139.334 1.00 29.90  ? 139 ARG A NH1   1 
ATOM 625  N NH2   . ARG A 1 83  ? 128.694 126.663 140.730 1.00 29.90  ? 139 ARG A NH2   1 
ATOM 626  N N     . TYR A 1 84  ? 132.791 129.885 145.775 1.00 27.71  ? 140 TYR A N     1 
ATOM 627  C CA    . TYR A 1 84  ? 132.571 130.687 146.983 1.00 27.71  ? 140 TYR A CA    1 
ATOM 628  C C     . TYR A 1 84  ? 133.883 131.270 147.467 1.00 27.71  ? 140 TYR A C     1 
ATOM 629  O O     . TYR A 1 84  ? 133.896 132.275 148.174 1.00 27.71  ? 140 TYR A O     1 
ATOM 630  C CB    . TYR A 1 84  ? 131.936 129.832 148.083 1.00 27.71  ? 140 TYR A CB    1 
ATOM 631  C CG    . TYR A 1 84  ? 131.171 130.635 149.108 1.00 27.71  ? 140 TYR A CG    1 
ATOM 632  C CD1   . TYR A 1 84  ? 129.875 131.054 148.854 1.00 27.71  ? 140 TYR A CD1   1 
ATOM 633  C CD2   . TYR A 1 84  ? 131.744 130.979 150.326 1.00 27.71  ? 140 TYR A CD2   1 
ATOM 634  C CE1   . TYR A 1 84  ? 129.169 131.791 149.780 1.00 27.71  ? 140 TYR A CE1   1 
ATOM 635  C CE2   . TYR A 1 84  ? 131.044 131.719 151.259 1.00 27.71  ? 140 TYR A CE2   1 
ATOM 636  C CZ    . TYR A 1 84  ? 129.756 132.120 150.979 1.00 27.71  ? 140 TYR A CZ    1 
ATOM 637  O OH    . TYR A 1 84  ? 129.048 132.857 151.895 1.00 27.71  ? 140 TYR A OH    1 
ATOM 638  N N     . ASP A 1 85  ? 134.988 130.660 147.069 1.00 33.89  ? 141 ASP A N     1 
ATOM 639  C CA    . ASP A 1 85  ? 136.304 131.092 147.507 1.00 33.89  ? 141 ASP A CA    1 
ATOM 640  C C     . ASP A 1 85  ? 137.002 131.892 146.425 1.00 33.89  ? 141 ASP A C     1 
ATOM 641  O O     . ASP A 1 85  ? 137.893 132.675 146.746 1.00 33.89  ? 141 ASP A O     1 
ATOM 642  C CB    . ASP A 1 85  ? 137.154 129.875 147.903 1.00 33.89  ? 141 ASP A CB    1 
ATOM 643  C CG    . ASP A 1 85  ? 138.146 130.185 149.004 1.00 33.89  ? 141 ASP A CG    1 
ATOM 644  O OD1   . ASP A 1 85  ? 138.506 131.368 149.171 1.00 33.89  ? 141 ASP A OD1   1 
ATOM 645  O OD2   . ASP A 1 85  ? 138.560 129.241 149.708 1.00 33.89  ? 141 ASP A OD2   1 
ATOM 646  N N     . GLY A 1 86  ? 136.592 131.773 145.168 1.00 37.32  ? 142 GLY A N     1 
ATOM 647  C CA    . GLY A 1 86  ? 137.040 132.682 144.137 1.00 37.32  ? 142 GLY A CA    1 
ATOM 648  C C     . GLY A 1 86  ? 136.406 134.046 144.302 1.00 37.32  ? 142 GLY A C     1 
ATOM 649  O O     . GLY A 1 86  ? 137.015 135.063 143.965 1.00 37.32  ? 142 GLY A O     1 
ATOM 650  N N     . VAL A 1 87  ? 135.179 134.081 144.830 1.00 37.45  ? 143 VAL A N     1 
ATOM 651  C CA    . VAL A 1 87  ? 134.558 135.366 145.148 1.00 37.45  ? 143 VAL A CA    1 
ATOM 652  C C     . VAL A 1 87  ? 135.358 136.089 146.218 1.00 37.45  ? 143 VAL A C     1 
ATOM 653  O O     . VAL A 1 87  ? 135.604 137.296 146.116 1.00 37.45  ? 143 VAL A O     1 
ATOM 654  C CB    . VAL A 1 87  ? 133.089 135.183 145.575 1.00 37.45  ? 143 VAL A CB    1 
ATOM 655  C CG1   . VAL A 1 87  ? 132.517 136.494 146.046 1.00 37.45  ? 143 VAL A CG1   1 
ATOM 656  C CG2   . VAL A 1 87  ? 132.274 134.660 144.419 1.00 37.45  ? 143 VAL A CG2   1 
ATOM 657  N N     . ILE A 1 88  ? 135.786 135.366 147.250 1.00 41.07  ? 144 ILE A N     1 
ATOM 658  C CA    . ILE A 1 88  ? 136.660 135.953 148.255 1.00 41.07  ? 144 ILE A CA    1 
ATOM 659  C C     . ILE A 1 88  ? 138.037 136.220 147.664 1.00 41.07  ? 144 ILE A C     1 
ATOM 660  O O     . ILE A 1 88  ? 138.745 137.129 148.109 1.00 41.07  ? 144 ILE A O     1 
ATOM 661  C CB    . ILE A 1 88  ? 136.736 135.029 149.481 1.00 41.07  ? 144 ILE A CB    1 
ATOM 662  C CG1   . ILE A 1 88  ? 135.331 134.665 149.956 1.00 41.07  ? 144 ILE A CG1   1 
ATOM 663  C CG2   . ILE A 1 88  ? 137.515 135.691 150.607 1.00 41.07  ? 144 ILE A CG2   1 
ATOM 664  C CD1   . ILE A 1 88  ? 135.301 134.007 151.305 1.00 41.07  ? 144 ILE A CD1   1 
ATOM 665  N N     . LYS A 1 89  ? 138.433 135.441 146.657 1.00 43.96  ? 145 LYS A N     1 
ATOM 666  C CA    . LYS A 1 89  ? 139.736 135.595 146.025 1.00 43.96  ? 145 LYS A CA    1 
ATOM 667  C C     . LYS A 1 89  ? 139.830 136.889 145.229 1.00 43.96  ? 145 LYS A C     1 
ATOM 668  O O     . LYS A 1 89  ? 140.896 137.504 145.180 1.00 43.96  ? 145 LYS A O     1 
ATOM 669  C CB    . LYS A 1 89  ? 140.018 134.388 145.131 1.00 43.96  ? 145 LYS A CB    1 
ATOM 670  C CG    . LYS A 1 89  ? 141.387 134.390 144.479 1.00 43.96  ? 145 LYS A CG    1 
ATOM 671  C CD    . LYS A 1 89  ? 141.616 133.107 143.698 1.00 43.96  ? 145 LYS A CD    1 
ATOM 672  C CE    . LYS A 1 89  ? 142.909 133.165 142.904 1.00 43.96  ? 145 LYS A CE    1 
ATOM 673  N NZ    . LYS A 1 89  ? 144.101 133.218 143.795 1.00 43.96  ? 145 LYS A NZ    1 
ATOM 674  N N     . LYS A 1 90  ? 138.725 137.333 144.642 1.00 44.57  ? 146 LYS A N     1 
ATOM 675  C CA    . LYS A 1 90  ? 138.731 138.604 143.921 1.00 44.57  ? 146 LYS A CA    1 
ATOM 676  C C     . LYS A 1 90  ? 138.997 139.749 144.895 1.00 44.57  ? 146 LYS A C     1 
ATOM 677  O O     . LYS A 1 90  ? 139.793 140.639 144.601 1.00 44.57  ? 146 LYS A O     1 
ATOM 678  C CB    . LYS A 1 90  ? 137.410 138.810 143.182 1.00 44.57  ? 146 LYS A CB    1 
ATOM 679  C CG    . LYS A 1 90  ? 137.470 139.864 142.089 1.00 44.57  ? 146 LYS A CG    1 
ATOM 680  C CD    . LYS A 1 90  ? 136.145 139.967 141.353 1.00 44.57  ? 146 LYS A CD    1 
ATOM 681  C CE    . LYS A 1 90  ? 135.745 138.629 140.755 1.00 44.57  ? 146 LYS A CE    1 
ATOM 682  N NZ    . LYS A 1 90  ? 134.434 138.701 140.054 1.00 44.57  ? 146 LYS A NZ    1 
ATOM 683  N N     . VAL A 1 91  ? 138.345 139.727 146.053 1.00 49.20  ? 147 VAL A N     1 
ATOM 684  C CA    . VAL A 1 91  ? 138.545 140.756 147.065 1.00 49.20  ? 147 VAL A CA    1 
ATOM 685  C C     . VAL A 1 91  ? 139.959 140.679 147.620 1.00 49.20  ? 147 VAL A C     1 
ATOM 686  O O     . VAL A 1 91  ? 140.635 141.698 147.790 1.00 49.20  ? 147 VAL A O     1 
ATOM 687  C CB    . VAL A 1 91  ? 137.491 140.619 148.180 1.00 49.20  ? 147 VAL A CB    1 
ATOM 688  C CG1   . VAL A 1 91  ? 137.899 141.423 149.398 1.00 49.20  ? 147 VAL A CG1   1 
ATOM 689  C CG2   . VAL A 1 91  ? 136.123 141.053 147.680 1.00 49.20  ? 147 VAL A CG2   1 
ATOM 690  N N     . GLU A 1 92  ? 140.428 139.465 147.906 1.00 53.00  ? 148 GLU A N     1 
ATOM 691  C CA    . GLU A 1 92  ? 141.765 139.280 148.447 1.00 53.00  ? 148 GLU A CA    1 
ATOM 692  C C     . GLU A 1 92  ? 142.859 139.708 147.479 1.00 53.00  ? 148 GLU A C     1 
ATOM 693  O O     . GLU A 1 92  ? 143.835 140.319 147.916 1.00 53.00  ? 148 GLU A O     1 
ATOM 694  C CB    . GLU A 1 92  ? 141.959 137.820 148.856 1.00 53.00  ? 148 GLU A CB    1 
ATOM 695  C CG    . GLU A 1 92  ? 141.185 137.433 150.105 1.00 53.00  ? 148 GLU A CG    1 
ATOM 696  C CD    . GLU A 1 92  ? 141.573 136.068 150.637 1.00 53.00  ? 148 GLU A CD    1 
ATOM 697  O OE1   . GLU A 1 92  ? 142.360 135.368 149.966 1.00 53.00  ? 148 GLU A OE1   1 
ATOM 698  O OE2   . GLU A 1 92  ? 141.090 135.694 151.727 1.00 53.00  ? 148 GLU A OE2   1 
ATOM 699  N N     . THR A 1 93  ? 142.724 139.421 146.185 1.00 55.71  ? 149 THR A N     1 
ATOM 700  C CA    . THR A 1 93  ? 143.698 139.865 145.197 1.00 55.71  ? 149 THR A CA    1 
ATOM 701  C C     . THR A 1 93  ? 143.672 141.369 144.989 1.00 55.71  ? 149 THR A C     1 
ATOM 702  O O     . THR A 1 93  ? 144.734 141.983 144.833 1.00 55.71  ? 149 THR A O     1 
ATOM 703  C CB    . THR A 1 93  ? 143.460 139.161 143.858 1.00 55.71  ? 149 THR A CB    1 
ATOM 704  O OG1   . THR A 1 93  ? 142.061 139.175 143.547 1.00 55.71  ? 149 THR A OG1   1 
ATOM 705  C CG2   . THR A 1 93  ? 143.951 137.721 143.918 1.00 55.71  ? 149 THR A CG2   1 
ATOM 706  N N     . ARG A 1 94  ? 142.487 141.984 144.979 1.00 58.97  ? 150 ARG A N     1 
ATOM 707  C CA    . ARG A 1 94  ? 142.440 143.440 144.913 1.00 58.97  ? 150 ARG A CA    1 
ATOM 708  C C     . ARG A 1 94  ? 143.070 144.064 146.151 1.00 58.97  ? 150 ARG A C     1 
ATOM 709  O O     . ARG A 1 94  ? 143.797 145.055 146.046 1.00 58.97  ? 150 ARG A O     1 
ATOM 710  C CB    . ARG A 1 94  ? 141.001 143.924 144.724 1.00 58.97  ? 150 ARG A CB    1 
ATOM 711  C CG    . ARG A 1 94  ? 140.531 143.856 143.279 1.00 58.97  ? 150 ARG A CG    1 
ATOM 712  C CD    . ARG A 1 94  ? 139.032 144.057 143.142 1.00 58.97  ? 150 ARG A CD    1 
ATOM 713  N NE    . ARG A 1 94  ? 138.548 145.191 143.917 1.00 58.97  ? 150 ARG A NE    1 
ATOM 714  C CZ    . ARG A 1 94  ? 137.653 145.105 144.891 1.00 58.97  ? 150 ARG A CZ    1 
ATOM 715  N NH1   . ARG A 1 94  ? 137.104 143.949 145.226 1.00 58.97  ? 150 ARG A NH1   1 
ATOM 716  N NH2   . ARG A 1 94  ? 137.294 146.208 145.542 1.00 58.97  ? 150 ARG A NH2   1 
ATOM 717  N N     . ASN A 1 95  ? 142.825 143.485 147.326 1.00 61.45  ? 151 ASN A N     1 
ATOM 718  C CA    . ASN A 1 95  ? 143.484 143.962 148.533 1.00 61.45  ? 151 ASN A CA    1 
ATOM 719  C C     . ASN A 1 95  ? 144.990 143.761 148.457 1.00 61.45  ? 151 ASN A C     1 
ATOM 720  O O     . ASN A 1 95  ? 145.753 144.592 148.958 1.00 61.45  ? 151 ASN A O     1 
ATOM 721  C CB    . ASN A 1 95  ? 142.914 143.248 149.757 1.00 61.45  ? 151 ASN A CB    1 
ATOM 722  C CG    . ASN A 1 95  ? 141.581 143.817 150.195 1.00 61.45  ? 151 ASN A CG    1 
ATOM 723  O OD1   . ASN A 1 95  ? 140.964 144.606 149.479 1.00 61.45  ? 151 ASN A OD1   1 
ATOM 724  N ND2   . ASN A 1 95  ? 141.125 143.414 151.376 1.00 61.45  ? 151 ASN A ND2   1 
ATOM 725  N N     . GLU A 1 96  ? 145.435 142.659 147.853 1.00 65.96  ? 152 GLU A N     1 
ATOM 726  C CA    . GLU A 1 96  ? 146.864 142.434 147.678 1.00 65.96  ? 152 GLU A CA    1 
ATOM 727  C C     . GLU A 1 96  ? 147.478 143.492 146.774 1.00 65.96  ? 152 GLU A C     1 
ATOM 728  O O     . GLU A 1 96  ? 148.570 143.999 147.050 1.00 65.96  ? 152 GLU A O     1 
ATOM 729  C CB    . GLU A 1 96  ? 147.109 141.036 147.111 1.00 65.96  ? 152 GLU A CB    1 
ATOM 730  C CG    . GLU A 1 96  ? 148.578 140.661 147.005 1.00 65.96  ? 152 GLU A CG    1 
ATOM 731  C CD    . GLU A 1 96  ? 148.788 139.302 146.367 1.00 65.96  ? 152 GLU A CD    1 
ATOM 732  O OE1   . GLU A 1 96  ? 147.785 138.650 146.009 1.00 65.96  ? 152 GLU A OE1   1 
ATOM 733  O OE2   . GLU A 1 96  ? 149.957 138.886 146.224 1.00 65.96  ? 152 GLU A OE2   1 
ATOM 734  N N     . LYS A 1 97  ? 146.790 143.838 145.686 1.00 68.35  ? 153 LYS A N     1 
ATOM 735  C CA    . LYS A 1 97  ? 147.278 144.916 144.831 1.00 68.35  ? 153 LYS A CA    1 
ATOM 736  C C     . LYS A 1 97  ? 147.262 146.249 145.568 1.00 68.35  ? 153 LYS A C     1 
ATOM 737  O O     . LYS A 1 97  ? 148.132 147.096 145.351 1.00 68.35  ? 153 LYS A O     1 
ATOM 738  C CB    . LYS A 1 97  ? 146.459 144.993 143.542 1.00 68.35  ? 153 LYS A CB    1 
ATOM 739  C CG    . LYS A 1 97  ? 146.583 143.760 142.660 1.00 68.35  ? 153 LYS A CG    1 
ATOM 740  C CD    . LYS A 1 97  ? 145.806 143.924 141.364 1.00 68.35  ? 153 LYS A CD    1 
ATOM 741  C CE    . LYS A 1 97  ? 144.311 143.892 141.610 1.00 68.35  ? 153 LYS A CE    1 
ATOM 742  N NZ    . LYS A 1 97  ? 143.875 142.552 142.089 1.00 68.35  ? 153 LYS A NZ    1 
ATOM 743  N N     . ARG A 1 98  ? 146.276 146.455 146.440 1.00 74.84  ? 154 ARG A N     1 
ATOM 744  C CA    . ARG A 1 98  ? 146.240 147.676 147.236 1.00 74.84  ? 154 ARG A CA    1 
ATOM 745  C C     . ARG A 1 98  ? 147.431 147.745 148.180 1.00 74.84  ? 154 ARG A C     1 
ATOM 746  O O     . ARG A 1 98  ? 148.050 148.803 148.342 1.00 74.84  ? 154 ARG A O     1 
ATOM 747  C CB    . ARG A 1 98  ? 144.928 147.756 148.016 1.00 74.84  ? 154 ARG A CB    1 
ATOM 748  C CG    . ARG A 1 98  ? 144.692 149.090 148.704 1.00 74.84  ? 154 ARG A CG    1 
ATOM 749  C CD    . ARG A 1 98  ? 143.235 149.252 149.106 1.00 74.84  ? 154 ARG A CD    1 
ATOM 750  N NE    . ARG A 1 98  ? 142.351 149.341 147.950 1.00 74.84  ? 154 ARG A NE    1 
ATOM 751  C CZ    . ARG A 1 98  ? 141.032 149.218 148.005 1.00 74.84  ? 154 ARG A CZ    1 
ATOM 752  N NH1   . ARG A 1 98  ? 140.406 148.995 149.149 1.00 74.84  ? 154 ARG A NH1   1 
ATOM 753  N NH2   . ARG A 1 98  ? 140.323 149.322 146.885 1.00 74.84  ? 154 ARG A NH2   1 
ATOM 754  N N     . ARG A 1 99  ? 147.770 146.621 148.810 1.00 81.48  ? 155 ARG A N     1 
ATOM 755  C CA    . ARG A 1 99  ? 148.951 146.572 149.662 1.00 81.48  ? 155 ARG A CA    1 
ATOM 756  C C     . ARG A 1 99  ? 150.233 146.749 148.860 1.00 81.48  ? 155 ARG A C     1 
ATOM 757  O O     . ARG A 1 99  ? 151.184 147.361 149.356 1.00 81.48  ? 155 ARG A O     1 
ATOM 758  C CB    . ARG A 1 99  ? 148.983 145.255 150.441 1.00 81.48  ? 155 ARG A CB    1 
ATOM 759  C CG    . ARG A 1 99  ? 150.139 145.136 151.422 1.00 81.48  ? 155 ARG A CG    1 
ATOM 760  C CD    . ARG A 1 99  ? 150.040 143.858 152.239 1.00 81.48  ? 155 ARG A CD    1 
ATOM 761  N NE    . ARG A 1 99  ? 148.909 143.889 153.160 1.00 81.48  ? 155 ARG A NE    1 
ATOM 762  C CZ    . ARG A 1 99  ? 148.489 142.849 153.867 1.00 81.48  ? 155 ARG A CZ    1 
ATOM 763  N NH1   . ARG A 1 99  ? 149.086 141.671 153.786 1.00 81.48  ? 155 ARG A NH1   1 
ATOM 764  N NH2   . ARG A 1 99  ? 147.444 142.994 154.676 1.00 81.48  ? 155 ARG A NH2   1 
ATOM 765  N N     . SER A 1 100 ? 150.273 146.241 147.629 1.00 86.35  ? 156 SER A N     1 
ATOM 766  C CA    . SER A 1 100 ? 151.403 146.499 146.745 1.00 86.35  ? 156 SER A CA    1 
ATOM 767  C C     . SER A 1 100 ? 151.523 147.977 146.397 1.00 86.35  ? 156 SER A C     1 
ATOM 768  O O     . SER A 1 100 ? 152.636 148.504 146.333 1.00 86.35  ? 156 SER A O     1 
ATOM 769  C CB    . SER A 1 100 ? 151.275 145.667 145.468 1.00 86.35  ? 156 SER A CB    1 
ATOM 770  O OG    . SER A 1 100 ? 152.316 145.969 144.556 1.00 86.35  ? 156 SER A OG    1 
ATOM 771  N N     . LYS A 1 101 ? 150.398 148.652 146.164 1.00 90.61  ? 157 LYS A N     1 
ATOM 772  C CA    . LYS A 1 101 ? 150.426 150.092 145.925 1.00 90.61  ? 157 LYS A CA    1 
ATOM 773  C C     . LYS A 1 101 ? 150.908 150.839 147.163 1.00 90.61  ? 157 LYS A C     1 
ATOM 774  O O     . LYS A 1 101 ? 151.648 151.828 147.060 1.00 90.61  ? 157 LYS A O     1 
ATOM 775  C CB    . LYS A 1 101 ? 149.038 150.571 145.498 1.00 90.61  ? 157 LYS A CB    1 
ATOM 776  C CG    . LYS A 1 101 ? 148.960 152.027 145.049 1.00 90.61  ? 157 LYS A CG    1 
ATOM 777  C CD    . LYS A 1 101 ? 148.576 152.959 146.191 1.00 90.61  ? 157 LYS A CD    1 
ATOM 778  C CE    . LYS A 1 101 ? 148.431 154.394 145.709 1.00 90.61  ? 157 LYS A CE    1 
ATOM 779  N NZ    . LYS A 1 101 ? 148.091 155.323 146.822 1.00 90.61  ? 157 LYS A NZ    1 
ATOM 780  N N     . ALA A 1 102 ? 150.485 150.384 148.343 1.00 96.99  ? 158 ALA A N     1 
ATOM 781  C CA    . ALA A 1 102 ? 150.984 150.967 149.583 1.00 96.99  ? 158 ALA A CA    1 
ATOM 782  C C     . ALA A 1 102 ? 152.491 150.782 149.704 1.00 96.99  ? 158 ALA A C     1 
ATOM 783  O O     . ALA A 1 102 ? 153.205 151.697 150.123 1.00 96.99  ? 158 ALA A O     1 
ATOM 784  C CB    . ALA A 1 102 ? 150.266 150.348 150.782 1.00 96.99  ? 158 ALA A CB    1 
ATOM 785  N N     . THR A 1 103 ? 152.987 149.619 149.299 1.00 100.52 ? 159 THR A N     1 
ATOM 786  C CA    . THR A 1 103 ? 154.427 149.382 149.320 1.00 100.52 ? 159 THR A CA    1 
ATOM 787  C C     . THR A 1 103 ? 155.108 150.325 148.337 1.00 100.52 ? 159 THR A C     1 
ATOM 788  O O     . THR A 1 103 ? 156.131 150.922 148.658 1.00 100.52 ? 159 THR A O     1 
ATOM 789  C CB    . THR A 1 103 ? 154.760 147.925 148.950 1.00 100.52 ? 159 THR A CB    1 
ATOM 790  O OG1   . THR A 1 103 ? 154.017 147.034 149.791 1.00 100.52 ? 159 THR A OG1   1 
ATOM 791  C CG2   . THR A 1 103 ? 156.248 147.649 149.116 1.00 100.52 ? 159 THR A CG2   1 
ATOM 792  N N     . ARG A 1 104 ? 154.535 150.474 147.146 1.00 102.56 ? 160 ARG A N     1 
ATOM 793  C CA    . ARG A 1 104 ? 155.126 151.338 146.128 1.00 102.56 ? 160 ARG A CA    1 
ATOM 794  C C     . ARG A 1 104 ? 155.253 152.771 146.628 1.00 102.56 ? 160 ARG A C     1 
ATOM 795  O O     . ARG A 1 104 ? 156.301 153.407 146.462 1.00 102.56 ? 160 ARG A O     1 
ATOM 796  C CB    . ARG A 1 104 ? 154.289 151.293 144.847 1.00 102.56 ? 160 ARG A CB    1 
ATOM 797  C CG    . ARG A 1 104 ? 154.308 149.962 144.113 1.00 102.56 ? 160 ARG A CG    1 
ATOM 798  C CD    . ARG A 1 104 ? 155.507 149.856 143.184 1.00 102.56 ? 160 ARG A CD    1 
ATOM 799  N NE    . ARG A 1 104 ? 156.697 149.366 143.869 1.00 102.56 ? 160 ARG A NE    1 
ATOM 800  C CZ    . ARG A 1 104 ? 156.921 148.093 144.162 1.00 102.56 ? 160 ARG A CZ    1 
ATOM 801  N NH1   . ARG A 1 104 ? 156.054 147.146 143.840 1.00 102.56 ? 160 ARG A NH1   1 
ATOM 802  N NH2   . ARG A 1 104 ? 158.043 147.760 144.793 1.00 102.56 ? 160 ARG A NH2   1 
ATOM 803  N N     . ILE A 1 105 ? 154.191 153.301 147.240 1.00 105.01 ? 161 ILE A N     1 
ATOM 804  C CA    . ILE A 1 105 ? 154.274 154.666 147.756 1.00 105.01 ? 161 ILE A CA    1 
ATOM 805  C C     . ILE A 1 105 ? 155.212 154.732 148.958 1.00 105.01 ? 161 ILE A C     1 
ATOM 806  O O     . ILE A 1 105 ? 155.910 155.734 149.155 1.00 105.01 ? 161 ILE A O     1 
ATOM 807  C CB    . ILE A 1 105 ? 152.875 155.226 148.084 1.00 105.01 ? 161 ILE A CB    1 
ATOM 808  C CG1   . ILE A 1 105 ? 152.179 154.397 149.162 1.00 105.01 ? 161 ILE A CG1   1 
ATOM 809  C CG2   . ILE A 1 105 ? 152.019 155.291 146.827 1.00 105.01 ? 161 ILE A CG2   1 
ATOM 810  C CD1   . ILE A 1 105 ? 150.899 155.015 149.681 1.00 105.01 ? 161 ILE A CD1   1 
ATOM 811  N N     . ASN A 1 106 ? 155.270 153.669 149.766 1.00 110.05 ? 162 ASN A N     1 
ATOM 812  C CA    . ASN A 1 106 ? 156.179 153.654 150.907 1.00 110.05 ? 162 ASN A CA    1 
ATOM 813  C C     . ASN A 1 106 ? 157.636 153.697 150.463 1.00 110.05 ? 162 ASN A C     1 
ATOM 814  O O     . ASN A 1 106 ? 158.474 154.304 151.139 1.00 110.05 ? 162 ASN A O     1 
ATOM 815  C CB    . ASN A 1 106 ? 155.921 152.419 151.770 1.00 110.05 ? 162 ASN A CB    1 
ATOM 816  C CG    . ASN A 1 106 ? 154.740 152.597 152.704 1.00 110.05 ? 162 ASN A CG    1 
ATOM 817  O OD1   . ASN A 1 106 ? 154.133 153.666 152.758 1.00 110.05 ? 162 ASN A OD1   1 
ATOM 818  N ND2   . ASN A 1 106 ? 154.410 151.547 153.446 1.00 110.05 ? 162 ASN A ND2   1 
ATOM 819  N N     . VAL A 1 107 ? 157.956 153.022 149.359 1.00 113.00 ? 163 VAL A N     1 
ATOM 820  C CA    . VAL A 1 107 ? 159.328 153.026 148.846 1.00 113.00 ? 163 VAL A CA    1 
ATOM 821  C C     . VAL A 1 107 ? 159.758 154.469 148.673 1.00 113.00 ? 163 VAL A C     1 
ATOM 822  O O     . VAL A 1 107 ? 160.772 154.894 149.233 1.00 113.00 ? 163 VAL A O     1 
ATOM 823  C CB    . VAL A 1 107 ? 159.455 152.264 147.510 1.00 113.00 ? 163 VAL A CB    1 
ATOM 824  C CG1   . VAL A 1 107 ? 160.794 152.554 146.847 1.00 113.00 ? 163 VAL A CG1   1 
ATOM 825  C CG2   . VAL A 1 107 ? 159.297 150.769 147.733 1.00 113.00 ? 163 VAL A CG2   1 
ATOM 826  N N     . SER A 1 108 ? 158.986 155.231 147.907 1.00 116.22 ? 164 SER A N     1 
ATOM 827  C CA    . SER A 1 108 ? 159.281 156.649 147.752 1.00 116.22 ? 164 SER A CA    1 
ATOM 828  C C     . SER A 1 108 ? 159.215 157.401 149.074 1.00 116.22 ? 164 SER A C     1 
ATOM 829  O O     . SER A 1 108 ? 159.890 158.426 149.219 1.00 116.22 ? 164 SER A O     1 
ATOM 830  C CB    . SER A 1 108 ? 158.317 157.281 146.745 1.00 116.22 ? 164 SER A CB    1 
ATOM 831  O OG    . SER A 1 108 ? 158.259 156.526 145.548 1.00 116.22 ? 164 SER A OG    1 
ATOM 832  N N     . ARG A 1 109 ? 158.421 156.906 150.023 1.00 118.45 ? 165 ARG A N     1 
ATOM 833  C CA    . ARG A 1 109 ? 158.313 157.540 151.339 1.00 118.45 ? 165 ARG A CA    1 
ATOM 834  C C     . ARG A 1 109 ? 159.635 157.519 152.096 1.00 118.45 ? 165 ARG A C     1 
ATOM 835  O O     . ARG A 1 109 ? 160.030 158.534 152.666 1.00 118.45 ? 165 ARG A O     1 
ATOM 836  C CB    . ARG A 1 109 ? 157.255 156.852 152.208 1.00 118.45 ? 165 ARG A CB    1 
ATOM 837  C CG    . ARG A 1 109 ? 155.836 157.316 151.976 1.00 118.45 ? 165 ARG A CG    1 
ATOM 838  C CD    . ARG A 1 109 ? 155.692 158.696 152.559 1.00 118.45 ? 165 ARG A CD    1 
ATOM 839  N NE    . ARG A 1 109 ? 154.555 159.419 152.020 1.00 118.45 ? 165 ARG A NE    1 
ATOM 840  C CZ    . ARG A 1 109 ? 154.387 160.713 152.225 1.00 118.45 ? 165 ARG A CZ    1 
ATOM 841  N NH1   . ARG A 1 109 ? 155.297 161.355 152.936 1.00 118.45 ? 165 ARG A NH1   1 
ATOM 842  N NH2   . ARG A 1 109 ? 153.344 161.358 151.722 1.00 118.45 ? 165 ARG A NH2   1 
ATOM 843  N N     . GLU A 1 110 ? 160.316 156.373 152.114 1.00 118.59 ? 166 GLU A N     1 
ATOM 844  C CA    . GLU A 1 110 ? 161.620 156.351 152.785 1.00 118.59 ? 166 GLU A CA    1 
ATOM 845  C C     . GLU A 1 110 ? 162.639 157.206 152.044 1.00 118.59 ? 166 GLU A C     1 
ATOM 846  O O     . GLU A 1 110 ? 163.488 157.841 152.681 1.00 118.59 ? 166 GLU A O     1 
ATOM 847  C CB    . GLU A 1 110 ? 162.224 154.947 152.978 1.00 118.59 ? 166 GLU A CB    1 
ATOM 848  C CG    . GLU A 1 110 ? 161.514 154.001 153.946 1.00 118.59 ? 166 GLU A CG    1 
ATOM 849  C CD    . GLU A 1 110 ? 160.475 153.141 153.283 1.00 118.59 ? 166 GLU A CD    1 
ATOM 850  O OE1   . GLU A 1 110 ? 160.410 153.180 152.044 1.00 118.59 ? 166 GLU A OE1   1 
ATOM 851  O OE2   . GLU A 1 110 ? 159.729 152.434 153.992 1.00 118.59 ? 166 GLU A OE2   1 
ATOM 852  N N     . ALA A 1 111 ? 162.582 157.226 150.710 1.00 120.39 ? 167 ALA A N     1 
ATOM 853  C CA    . ALA A 1 111 ? 163.495 158.069 149.944 1.00 120.39 ? 167 ALA A CA    1 
ATOM 854  C C     . ALA A 1 111 ? 163.296 159.541 150.281 1.00 120.39 ? 167 ALA A C     1 
ATOM 855  O O     . ALA A 1 111 ? 164.268 160.292 150.421 1.00 120.39 ? 167 ALA A O     1 
ATOM 856  C CB    . ALA A 1 111 ? 163.301 157.829 148.448 1.00 120.39 ? 167 ALA A CB    1 
ATOM 857  N N     . ASP A 1 112 ? 162.039 159.973 150.411 1.00 122.28 ? 168 ASP A N     1 
ATOM 858  C CA    . ASP A 1 112 ? 161.769 161.343 150.829 1.00 122.28 ? 168 ASP A CA    1 
ATOM 859  C C     . ASP A 1 112 ? 162.107 161.560 152.298 1.00 122.28 ? 168 ASP A C     1 
ATOM 860  O O     . ASP A 1 112 ? 162.487 162.670 152.688 1.00 122.28 ? 168 ASP A O     1 
ATOM 861  C CB    . ASP A 1 112 ? 160.305 161.696 150.561 1.00 122.28 ? 168 ASP A CB    1 
ATOM 862  C CG    . ASP A 1 112 ? 159.964 161.686 149.084 1.00 122.28 ? 168 ASP A CG    1 
ATOM 863  O OD1   . ASP A 1 112 ? 160.899 161.628 148.258 1.00 122.28 ? 168 ASP A OD1   1 
ATOM 864  O OD2   . ASP A 1 112 ? 158.762 161.740 148.749 1.00 122.28 ? 168 ASP A OD2   1 
ATOM 865  N N     . GLY A 1 113 ? 161.975 160.522 153.124 1.00 123.86 ? 169 GLY A N     1 
ATOM 866  C CA    . GLY A 1 113 ? 162.249 160.621 154.541 1.00 123.86 ? 169 GLY A CA    1 
ATOM 867  C C     . GLY A 1 113 ? 161.071 161.037 155.395 1.00 123.86 ? 169 GLY A C     1 
ATOM 868  O O     . GLY A 1 113 ? 161.195 161.052 156.627 1.00 123.86 ? 169 GLY A O     1 
ATOM 869  N N     . LEU A 1 114 ? 159.937 161.375 154.787 1.00 124.17 ? 170 LEU A N     1 
ATOM 870  C CA    . LEU A 1 114 ? 158.766 161.782 155.540 1.00 124.17 ? 170 LEU A CA    1 
ATOM 871  C C     . LEU A 1 114 ? 158.103 160.570 156.194 1.00 124.17 ? 170 LEU A C     1 
ATOM 872  O O     . LEU A 1 114 ? 158.298 159.433 155.759 1.00 124.17 ? 170 LEU A O     1 
ATOM 873  C CB    . LEU A 1 114 ? 157.775 162.497 154.625 1.00 124.17 ? 170 LEU A CB    1 
ATOM 874  C CG    . LEU A 1 114 ? 158.256 163.814 154.014 1.00 124.17 ? 170 LEU A CG    1 
ATOM 875  C CD1   . LEU A 1 114 ? 157.218 164.372 153.052 1.00 124.17 ? 170 LEU A CD1   1 
ATOM 876  C CD2   . LEU A 1 114 ? 158.581 164.824 155.104 1.00 124.17 ? 170 LEU A CD2   1 
ATOM 877  N N     . PRO A 1 115 ? 157.330 160.788 157.257 1.00 122.72 ? 171 PRO A N     1 
ATOM 878  C CA    . PRO A 1 115 ? 156.579 159.684 157.845 1.00 122.72 ? 171 PRO A CA    1 
ATOM 879  C C     . PRO A 1 115 ? 155.555 159.153 156.864 1.00 122.72 ? 171 PRO A C     1 
ATOM 880  O O     . PRO A 1 115 ? 155.063 159.893 155.991 1.00 122.72 ? 171 PRO A O     1 
ATOM 881  C CB    . PRO A 1 115 ? 155.910 160.323 159.071 1.00 122.72 ? 171 PRO A CB    1 
ATOM 882  C CG    . PRO A 1 115 ? 155.938 161.792 158.813 1.00 122.72 ? 171 PRO A CG    1 
ATOM 883  C CD    . PRO A 1 115 ? 157.189 162.030 158.036 1.00 122.72 ? 171 PRO A CD    1 
ATOM 884  N N     . PRO A 1 116 ? 155.212 157.868 156.958 1.00 119.52 ? 172 PRO A N     1 
ATOM 885  C CA    . PRO A 1 116 ? 154.268 157.283 155.997 1.00 119.52 ? 172 PRO A CA    1 
ATOM 886  C C     . PRO A 1 116 ? 152.913 157.975 156.036 1.00 119.52 ? 172 PRO A C     1 
ATOM 887  O O     . PRO A 1 116 ? 152.427 158.378 157.096 1.00 119.52 ? 172 PRO A O     1 
ATOM 888  C CB    . PRO A 1 116 ? 154.164 155.820 156.447 1.00 119.52 ? 172 PRO A CB    1 
ATOM 889  C CG    . PRO A 1 116 ? 155.411 155.570 157.231 1.00 119.52 ? 172 PRO A CG    1 
ATOM 890  C CD    . PRO A 1 116 ? 155.725 156.868 157.909 1.00 119.52 ? 172 PRO A CD    1 
ATOM 891  N N     . ILE A 1 117 ? 152.304 158.109 154.859 1.00 115.47 ? 173 ILE A N     1 
ATOM 892  C CA    . ILE A 1 117 ? 151.010 158.767 154.747 1.00 115.47 ? 173 ILE A CA    1 
ATOM 893  C C     . ILE A 1 117 ? 149.893 157.763 155.017 1.00 115.47 ? 173 ILE A C     1 
ATOM 894  O O     . ILE A 1 117 ? 150.097 156.546 155.024 1.00 115.47 ? 173 ILE A O     1 
ATOM 895  C CB    . ILE A 1 117 ? 150.850 159.430 153.365 1.00 115.47 ? 173 ILE A CB    1 
ATOM 896  C CG1   . ILE A 1 117 ? 149.929 160.651 153.453 1.00 115.47 ? 173 ILE A CG1   1 
ATOM 897  C CG2   . ILE A 1 117 ? 150.329 158.428 152.343 1.00 115.47 ? 173 ILE A CG2   1 
ATOM 898  C CD1   . ILE A 1 117 ? 150.498 161.787 154.273 1.00 115.47 ? 173 ILE A CD1   1 
ATOM 899  N N     . GLU A 1 118 ? 148.693 158.290 155.254 1.00 110.71 ? 174 GLU A N     1 
ATOM 900  C CA    . GLU A 1 118 ? 147.539 157.442 155.518 1.00 110.71 ? 174 GLU A CA    1 
ATOM 901  C C     . GLU A 1 118 ? 147.202 156.595 154.296 1.00 110.71 ? 174 GLU A C     1 
ATOM 902  O O     . GLU A 1 118 ? 147.339 157.031 153.149 1.00 110.71 ? 174 GLU A O     1 
ATOM 903  C CB    . GLU A 1 118 ? 146.334 158.295 155.916 1.00 110.71 ? 174 GLU A CB    1 
ATOM 904  C CG    . GLU A 1 118 ? 145.346 157.591 156.832 1.00 110.71 ? 174 GLU A CG    1 
ATOM 905  C CD    . GLU A 1 118 ? 144.212 156.933 156.070 1.00 110.71 ? 174 GLU A CD    1 
ATOM 906  O OE1   . GLU A 1 118 ? 143.995 157.296 154.895 1.00 110.71 ? 174 GLU A OE1   1 
ATOM 907  O OE2   . GLU A 1 118 ? 143.537 156.055 156.647 1.00 110.71 ? 174 GLU A OE2   1 
ATOM 908  N N     . ALA A 1 119 ? 146.754 155.368 154.552 1.00 101.81 ? 175 ALA A N     1 
ATOM 909  C CA    . ALA A 1 119 ? 146.423 154.414 153.506 1.00 101.81 ? 175 ALA A CA    1 
ATOM 910  C C     . ALA A 1 119 ? 144.924 154.150 153.496 1.00 101.81 ? 175 ALA A C     1 
ATOM 911  O O     . ALA A 1 119 ? 144.272 154.128 154.545 1.00 101.81 ? 175 ALA A O     1 
ATOM 912  C CB    . ALA A 1 119 ? 147.183 153.095 153.694 1.00 101.81 ? 175 ALA A CB    1 
ATOM 913  N N     . GLU A 1 120 ? 144.385 153.950 152.297 1.00 91.41  ? 176 GLU A N     1 
ATOM 914  C CA    . GLU A 1 120 ? 142.959 153.717 152.147 1.00 91.41  ? 176 GLU A CA    1 
ATOM 915  C C     . GLU A 1 120 ? 142.564 152.387 152.788 1.00 91.41  ? 176 GLU A C     1 
ATOM 916  O O     . GLU A 1 120 ? 143.367 151.451 152.844 1.00 91.41  ? 176 GLU A O     1 
ATOM 917  C CB    . GLU A 1 120 ? 142.570 153.717 150.670 1.00 91.41  ? 176 GLU A CB    1 
ATOM 918  C CG    . GLU A 1 120 ? 142.528 155.098 150.036 1.00 91.41  ? 176 GLU A CG    1 
ATOM 919  C CD    . GLU A 1 120 ? 143.883 155.547 149.524 1.00 91.41  ? 176 GLU A CD    1 
ATOM 920  O OE1   . GLU A 1 120 ? 144.793 154.697 149.422 1.00 91.41  ? 176 GLU A OE1   1 
ATOM 921  O OE2   . GLU A 1 120 ? 144.037 156.749 149.221 1.00 91.41  ? 176 GLU A OE2   1 
ATOM 922  N N     . PRO A 1 121 ? 141.332 152.281 153.291 1.00 80.16  ? 177 PRO A N     1 
ATOM 923  C CA    . PRO A 1 121 ? 140.891 151.017 153.893 1.00 80.16  ? 177 PRO A CA    1 
ATOM 924  C C     . PRO A 1 121 ? 140.638 149.936 152.855 1.00 80.16  ? 177 PRO A C     1 
ATOM 925  O O     . PRO A 1 121 ? 140.538 150.222 151.659 1.00 80.16  ? 177 PRO A O     1 
ATOM 926  C CB    . PRO A 1 121 ? 139.601 151.409 154.624 1.00 80.16  ? 177 PRO A CB    1 
ATOM 927  C CG    . PRO A 1 121 ? 139.090 152.585 153.868 1.00 80.16  ? 177 PRO A CG    1 
ATOM 928  C CD    . PRO A 1 121 ? 140.302 153.330 153.382 1.00 80.16  ? 177 PRO A CD    1 
ATOM 929  N N     . GLU A 1 122 ? 140.531 148.692 153.308 1.00 64.65  ? 178 GLU A N     1 
ATOM 930  C CA    . GLU A 1 122 ? 140.319 147.535 152.453 1.00 64.65  ? 178 GLU A CA    1 
ATOM 931  C C     . GLU A 1 122 ? 138.855 147.117 152.502 1.00 64.65  ? 178 GLU A C     1 
ATOM 932  O O     . GLU A 1 122 ? 138.031 147.728 153.187 1.00 64.65  ? 178 GLU A O     1 
ATOM 933  C CB    . GLU A 1 122 ? 141.236 146.385 152.873 1.00 64.65  ? 178 GLU A CB    1 
ATOM 934  C CG    . GLU A 1 122 ? 140.903 145.797 154.236 1.00 64.65  ? 178 GLU A CG    1 
ATOM 935  C CD    . GLU A 1 122 ? 141.929 144.782 154.701 1.00 64.65  ? 178 GLU A CD    1 
ATOM 936  O OE1   . GLU A 1 122 ? 143.039 144.752 154.130 1.00 64.65  ? 178 GLU A OE1   1 
ATOM 937  O OE2   . GLU A 1 122 ? 141.625 144.015 155.638 1.00 64.65  ? 178 GLU A OE2   1 
ATOM 938  N N     . GLU A 1 123 ? 138.534 146.056 151.769 1.00 51.11  ? 179 GLU A N     1 
ATOM 939  C CA    . GLU A 1 123 ? 137.166 145.576 151.650 1.00 51.11  ? 179 GLU A CA    1 
ATOM 940  C C     . GLU A 1 123 ? 137.119 144.075 151.886 1.00 51.11  ? 179 GLU A C     1 
ATOM 941  O O     . GLU A 1 123 ? 138.139 143.385 151.863 1.00 51.11  ? 179 GLU A O     1 
ATOM 942  C CB    . GLU A 1 123 ? 136.572 145.913 150.277 1.00 51.11  ? 179 GLU A CB    1 
ATOM 943  N N     . THR A 1 124 ? 135.909 143.577 152.143 1.00 42.90  ? 180 THR A N     1 
ATOM 944  C CA    . THR A 1 124 ? 135.658 142.144 152.234 1.00 42.90  ? 180 THR A CA    1 
ATOM 945  C C     . THR A 1 124 ? 134.517 141.762 151.305 1.00 42.90  ? 180 THR A C     1 
ATOM 946  O O     . THR A 1 124 ? 133.987 142.612 150.583 1.00 42.90  ? 180 THR A O     1 
ATOM 947  C CB    . THR A 1 124 ? 135.318 141.723 153.664 1.00 42.90  ? 180 THR A CB    1 
ATOM 948  O OG1   . THR A 1 124 ? 134.097 142.351 154.073 1.00 42.90  ? 180 THR A OG1   1 
ATOM 949  C CG2   . THR A 1 124 ? 136.434 142.118 154.622 1.00 42.90  ? 180 THR A CG2   1 
ATOM 950  N N     . ALA A 1 125 ? 134.132 140.490 151.313 1.00 37.41  ? 181 ALA A N     1 
ATOM 951  C CA    . ALA A 1 125 ? 132.991 140.022 150.544 1.00 37.41  ? 181 ALA A CA    1 
ATOM 952  C C     . ALA A 1 125 ? 131.772 139.757 151.413 1.00 37.41  ? 181 ALA A C     1 
ATOM 953  O O     . ALA A 1 125 ? 130.722 139.368 150.888 1.00 37.41  ? 181 ALA A O     1 
ATOM 954  C CB    . ALA A 1 125 ? 133.360 138.757 149.764 1.00 37.41  ? 181 ALA A CB    1 
ATOM 955  N N     . PHE A 1 126 ? 131.881 139.958 152.722 1.00 36.05  ? 182 PHE A N     1 
ATOM 956  C CA    . PHE A 1 126 ? 130.779 139.773 153.651 1.00 36.05  ? 182 PHE A CA    1 
ATOM 957  C C     . PHE A 1 126 ? 130.372 141.123 154.228 1.00 36.05  ? 182 PHE A C     1 
ATOM 958  O O     . PHE A 1 126 ? 131.220 141.990 154.462 1.00 36.05  ? 182 PHE A O     1 
ATOM 959  C CB    . PHE A 1 126 ? 131.162 138.814 154.785 1.00 36.05  ? 182 PHE A CB    1 
ATOM 960  C CG    . PHE A 1 126 ? 131.480 137.421 154.327 1.00 36.05  ? 182 PHE A CG    1 
ATOM 961  C CD1   . PHE A 1 126 ? 132.739 137.105 153.853 1.00 36.05  ? 182 PHE A CD1   1 
ATOM 962  C CD2   . PHE A 1 126 ? 130.531 136.426 154.389 1.00 36.05  ? 182 PHE A CD2   1 
ATOM 963  C CE1   . PHE A 1 126 ? 133.038 135.834 153.437 1.00 36.05  ? 182 PHE A CE1   1 
ATOM 964  C CE2   . PHE A 1 126 ? 130.823 135.144 153.972 1.00 36.05  ? 182 PHE A CE2   1 
ATOM 965  C CZ    . PHE A 1 126 ? 132.081 134.849 153.496 1.00 36.05  ? 182 PHE A CZ    1 
ATOM 966  N N     . GLY A 1 127 ? 129.071 141.298 154.440 1.00 39.63  ? 183 GLY A N     1 
ATOM 967  C CA    . GLY A 1 127 ? 128.550 142.489 155.066 1.00 39.63  ? 183 GLY A CA    1 
ATOM 968  C C     . GLY A 1 127 ? 128.488 142.344 156.572 1.00 39.63  ? 183 GLY A C     1 
ATOM 969  O O     . GLY A 1 127 ? 129.143 141.481 157.163 1.00 39.63  ? 183 GLY A O     1 
ATOM 970  N N     . PRO A 1 128 ? 127.687 143.186 157.227 1.00 43.50  ? 184 PRO A N     1 
ATOM 971  C CA    . PRO A 1 128 ? 127.628 143.140 158.693 1.00 43.50  ? 184 PRO A CA    1 
ATOM 972  C C     . PRO A 1 128 ? 126.743 142.037 159.241 1.00 43.50  ? 184 PRO A C     1 
ATOM 973  O O     . PRO A 1 128 ? 126.903 141.669 160.413 1.00 43.50  ? 184 PRO A O     1 
ATOM 974  C CB    . PRO A 1 128 ? 127.080 144.524 159.071 1.00 43.50  ? 184 PRO A CB    1 
ATOM 975  C CG    . PRO A 1 128 ? 126.481 145.096 157.806 1.00 43.50  ? 184 PRO A CG    1 
ATOM 976  C CD    . PRO A 1 128 ? 126.744 144.162 156.661 1.00 43.50  ? 184 PRO A CD    1 
ATOM 977  N N     . ASP A 1 129 ? 125.821 141.497 158.444 1.00 45.06  ? 185 ASP A N     1 
ATOM 978  C CA    . ASP A 1 129 ? 124.912 140.464 158.923 1.00 45.06  ? 185 ASP A CA    1 
ATOM 979  C C     . ASP A 1 129 ? 125.533 139.074 158.919 1.00 45.06  ? 185 ASP A C     1 
ATOM 980  O O     . ASP A 1 129 ? 124.905 138.131 159.413 1.00 45.06  ? 185 ASP A O     1 
ATOM 981  C CB    . ASP A 1 129 ? 123.635 140.456 158.077 1.00 45.06  ? 185 ASP A CB    1 
ATOM 982  C CG    . ASP A 1 129 ? 122.452 139.854 158.811 1.00 45.06  ? 185 ASP A CG    1 
ATOM 983  O OD1   . ASP A 1 129 ? 122.500 139.777 160.057 1.00 45.06  ? 185 ASP A OD1   1 
ATOM 984  O OD2   . ASP A 1 129 ? 121.476 139.456 158.142 1.00 45.06  ? 185 ASP A OD2   1 
ATOM 985  N N     . GLY A 1 130 ? 126.743 138.922 158.382 1.00 38.30  ? 186 GLY A N     1 
ATOM 986  C CA    . GLY A 1 130 ? 127.385 137.633 158.289 1.00 38.30  ? 186 GLY A CA    1 
ATOM 987  C C     . GLY A 1 130 ? 127.200 136.920 156.969 1.00 38.30  ? 186 GLY A C     1 
ATOM 988  O O     . GLY A 1 130 ? 127.959 135.989 156.676 1.00 38.30  ? 186 GLY A O     1 
ATOM 989  N N     . LYS A 1 131 ? 126.251 137.377 156.160 1.00 33.93  ? 187 LYS A N     1 
ATOM 990  C CA    . LYS A 1 131 ? 126.018 136.774 154.853 1.00 33.93  ? 187 LYS A CA    1 
ATOM 991  C C     . LYS A 1 131 ? 126.913 137.387 153.787 1.00 33.93  ? 187 LYS A C     1 
ATOM 992  O O     . LYS A 1 131 ? 127.421 138.495 153.959 1.00 33.93  ? 187 LYS A O     1 
ATOM 993  C CB    . LYS A 1 131 ? 124.548 136.920 154.457 1.00 33.93  ? 187 LYS A CB    1 
ATOM 994  C CG    . LYS A 1 131 ? 123.921 135.639 153.935 1.00 33.93  ? 187 LYS A CG    1 
ATOM 995  C CD    . LYS A 1 131 ? 124.038 134.517 154.955 1.00 33.93  ? 187 LYS A CD    1 
ATOM 996  C CE    . LYS A 1 131 ? 123.214 134.797 156.202 1.00 33.93  ? 187 LYS A CE    1 
ATOM 997  N NZ    . LYS A 1 131 ? 123.408 133.742 157.234 1.00 33.93  ? 187 LYS A NZ    1 
ATOM 998  N N     . LEU A 1 132 ? 127.107 136.672 152.685 1.00 37.22  ? 188 LEU A N     1 
ATOM 999  C CA    . LEU A 1 132 ? 127.954 137.166 151.604 1.00 37.22  ? 188 LEU A CA    1 
ATOM 1000 C C     . LEU A 1 132 ? 127.334 138.372 150.909 1.00 37.22  ? 188 LEU A C     1 
ATOM 1001 O O     . LEU A 1 132 ? 126.114 138.476 150.816 1.00 37.22  ? 188 LEU A O     1 
ATOM 1002 C CB    . LEU A 1 132 ? 128.202 136.047 150.590 1.00 37.22  ? 188 LEU A CB    1 
ATOM 1003 C CG    . LEU A 1 132 ? 129.366 136.186 149.607 1.00 37.22  ? 188 LEU A CG    1 
ATOM 1004 C CD1   . LEU A 1 132 ? 130.693 136.099 150.335 1.00 37.22  ? 188 LEU A CD1   1 
ATOM 1005 C CD2   . LEU A 1 132 ? 129.288 135.090 148.563 1.00 37.22  ? 188 LEU A CD2   1 
ATOM 1006 N N     . LYS A 1 133 ? 128.165 139.296 150.438 1.00 39.00  ? 189 LYS A N     1 
ATOM 1007 C CA    . LYS A 1 133 ? 127.658 140.451 149.703 1.00 39.00  ? 189 LYS A CA    1 
ATOM 1008 C C     . LYS A 1 133 ? 127.506 140.122 148.226 1.00 39.00  ? 189 LYS A C     1 
ATOM 1009 O O     . LYS A 1 133 ? 126.396 140.178 147.695 1.00 39.00  ? 189 LYS A O     1 
ATOM 1010 C CB    . LYS A 1 133 ? 128.564 141.669 149.877 1.00 39.00  ? 189 LYS A CB    1 
ATOM 1011 C CG    . LYS A 1 133 ? 128.403 142.370 151.212 1.00 39.00  ? 189 LYS A CG    1 
ATOM 1012 C CD    . LYS A 1 133 ? 129.255 143.625 151.276 1.00 39.00  ? 189 LYS A CD    1 
ATOM 1013 C CE    . LYS A 1 133 ? 130.712 143.308 150.990 1.00 39.00  ? 189 LYS A CE    1 
ATOM 1014 N NZ    . LYS A 1 133 ? 131.586 144.505 151.127 1.00 39.00  ? 189 LYS A NZ    1 
ATOM 1015 N N     . GLU A 1 134 ? 128.605 139.779 147.553 1.00 39.48  ? 190 GLU A N     1 
ATOM 1016 C CA    . GLU A 1 134 ? 128.474 139.376 146.155 1.00 39.48  ? 190 GLU A CA    1 
ATOM 1017 C C     . GLU A 1 134 ? 128.118 137.897 146.123 1.00 39.48  ? 190 GLU A C     1 
ATOM 1018 O O     . GLU A 1 134 ? 128.980 137.034 145.960 1.00 39.48  ? 190 GLU A O     1 
ATOM 1019 C CB    . GLU A 1 134 ? 129.764 139.656 145.398 1.00 39.48  ? 190 GLU A CB    1 
ATOM 1020 C CG    . GLU A 1 134 ? 130.071 141.130 145.223 1.00 39.48  ? 190 GLU A CG    1 
ATOM 1021 C CD    . GLU A 1 134 ? 130.830 141.700 146.404 1.00 39.48  ? 190 GLU A CD    1 
ATOM 1022 O OE1   . GLU A 1 134 ? 131.023 140.963 147.393 1.00 39.48  ? 190 GLU A OE1   1 
ATOM 1023 O OE2   . GLU A 1 134 ? 131.235 142.879 146.341 1.00 39.48  ? 190 GLU A OE2   1 
ATOM 1024 N N     . ARG A 1 135 ? 126.833 137.597 146.297 1.00 35.57  ? 191 ARG A N     1 
ATOM 1025 C CA    . ARG A 1 135 ? 126.381 136.207 146.281 1.00 35.57  ? 191 ARG A CA    1 
ATOM 1026 C C     . ARG A 1 135 ? 126.307 135.700 144.854 1.00 35.57  ? 191 ARG A C     1 
ATOM 1027 O O     . ARG A 1 135 ? 125.594 136.267 144.026 1.00 35.57  ? 191 ARG A O     1 
ATOM 1028 C CB    . ARG A 1 135 ? 125.014 136.081 146.948 1.00 35.57  ? 191 ARG A CB    1 
ATOM 1029 C CG    . ARG A 1 135 ? 124.961 136.674 148.341 1.00 35.57  ? 191 ARG A CG    1 
ATOM 1030 C CD    . ARG A 1 135 ? 123.566 136.587 148.935 1.00 35.57  ? 191 ARG A CD    1 
ATOM 1031 N NE    . ARG A 1 135 ? 123.445 137.398 150.142 1.00 35.57  ? 191 ARG A NE    1 
ATOM 1032 C CZ    . ARG A 1 135 ? 122.328 137.520 150.851 1.00 35.57  ? 191 ARG A CZ    1 
ATOM 1033 N NH1   . ARG A 1 135 ? 121.229 136.880 150.476 1.00 35.57  ? 191 ARG A NH1   1 
ATOM 1034 N NH2   . ARG A 1 135 ? 122.309 138.283 151.934 1.00 35.57  ? 191 ARG A NH2   1 
ATOM 1035 N N     . PRO A 1 136 ? 127.047 134.626 144.556 1.00 34.18  ? 192 PRO A N     1 
ATOM 1036 C CA    . PRO A 1 136 ? 127.071 134.108 143.188 1.00 34.18  ? 192 PRO A CA    1 
ATOM 1037 C C     . PRO A 1 136 ? 125.774 133.440 142.785 1.00 34.18  ? 192 PRO A C     1 
ATOM 1038 O O     . PRO A 1 136 ? 125.169 132.737 143.596 1.00 34.18  ? 192 PRO A O     1 
ATOM 1039 C CB    . PRO A 1 136 ? 128.208 133.079 143.218 1.00 34.18  ? 192 PRO A CB    1 
ATOM 1040 C CG    . PRO A 1 136 ? 128.996 133.401 144.442 1.00 34.18  ? 192 PRO A CG    1 
ATOM 1041 C CD    . PRO A 1 136 ? 127.994 133.916 145.424 1.00 34.18  ? 192 PRO A CD    1 
ATOM 1042 N N     . GLY A 1 137 ? 125.349 133.654 141.548 1.00 32.43  ? 193 GLY A N     1 
ATOM 1043 C CA    . GLY A 1 137 ? 124.139 133.055 141.043 1.00 32.43  ? 193 GLY A CA    1 
ATOM 1044 C C     . GLY A 1 137 ? 124.303 131.575 140.776 1.00 32.43  ? 193 GLY A C     1 
ATOM 1045 O O     . GLY A 1 137 ? 125.400 131.022 140.793 1.00 32.43  ? 193 GLY A O     1 
ATOM 1046 N N     . ILE A 1 138 ? 123.177 130.925 140.514 1.00 30.72  ? 194 ILE A N     1 
ATOM 1047 C CA    . ILE A 1 138 ? 123.154 129.479 140.344 1.00 30.72  ? 194 ILE A CA    1 
ATOM 1048 C C     . ILE A 1 138 ? 123.538 129.139 138.909 1.00 30.72  ? 194 ILE A C     1 
ATOM 1049 O O     . ILE A 1 138 ? 122.848 129.527 137.961 1.00 30.72  ? 194 ILE A O     1 
ATOM 1050 C CB    . ILE A 1 138 ? 121.777 128.906 140.697 1.00 30.72  ? 194 ILE A CB    1 
ATOM 1051 C CG1   . ILE A 1 138 ? 121.247 129.559 141.972 1.00 30.72  ? 194 ILE A CG1   1 
ATOM 1052 C CG2   . ILE A 1 138 ? 121.859 127.399 140.858 1.00 30.72  ? 194 ILE A CG2   1 
ATOM 1053 C CD1   . ILE A 1 138 ? 122.093 129.291 143.199 1.00 30.72  ? 194 ILE A CD1   1 
ATOM 1054 N N     . ASN A 1 139 ? 124.640 128.419 138.751 1.00 28.82  ? 195 ASN A N     1 
ATOM 1055 C CA    . ASN A 1 139 ? 125.018 127.868 137.457 1.00 28.82  ? 195 ASN A CA    1 
ATOM 1056 C C     . ASN A 1 139 ? 124.043 126.759 137.091 1.00 28.82  ? 195 ASN A C     1 
ATOM 1057 O O     . ASN A 1 139 ? 123.863 125.828 137.884 1.00 28.82  ? 195 ASN A O     1 
ATOM 1058 C CB    . ASN A 1 139 ? 126.440 127.330 137.524 1.00 28.82  ? 195 ASN A CB    1 
ATOM 1059 C CG    . ASN A 1 139 ? 127.152 127.382 136.198 1.00 28.82  ? 195 ASN A CG    1 
ATOM 1060 O OD1   . ASN A 1 139 ? 126.527 127.446 135.145 1.00 28.82  ? 195 ASN A OD1   1 
ATOM 1061 N ND2   . ASN A 1 139 ? 128.476 127.339 136.240 1.00 28.82  ? 195 ASN A ND2   1 
ATOM 1062 N N     . PRO A 1 140 ? 123.395 126.808 135.929 1.00 29.30  ? 196 PRO A N     1 
ATOM 1063 C CA    . PRO A 1 140 ? 122.429 125.763 135.563 1.00 29.30  ? 196 PRO A CA    1 
ATOM 1064 C C     . PRO A 1 140 ? 123.019 124.573 134.821 1.00 29.30  ? 196 PRO A C     1 
ATOM 1065 O O     . PRO A 1 140 ? 122.249 123.765 134.294 1.00 29.30  ? 196 PRO A O     1 
ATOM 1066 C CB    . PRO A 1 140 ? 121.454 126.522 134.653 1.00 29.30  ? 196 PRO A CB    1 
ATOM 1067 C CG    . PRO A 1 140 ? 122.252 127.668 134.083 1.00 29.30  ? 196 PRO A CG    1 
ATOM 1068 C CD    . PRO A 1 140 ? 123.528 127.816 134.868 1.00 29.30  ? 196 PRO A CD    1 
ATOM 1069 N N     . SER A 1 141 ? 124.340 124.444 134.770 1.00 28.97  ? 197 SER A N     1 
ATOM 1070 C CA    . SER A 1 141 ? 124.960 123.403 133.964 1.00 28.97  ? 197 SER A CA    1 
ATOM 1071 C C     . SER A 1 141 ? 124.730 122.030 134.580 1.00 28.97  ? 197 SER A C     1 
ATOM 1072 O O     . SER A 1 141 ? 124.974 121.819 135.772 1.00 28.97  ? 197 SER A O     1 
ATOM 1073 C CB    . SER A 1 141 ? 126.452 123.676 133.814 1.00 28.97  ? 197 SER A CB    1 
ATOM 1074 O OG    . SER A 1 141 ? 126.667 124.925 133.191 1.00 28.97  ? 197 SER A OG    1 
ATOM 1075 N N     . ILE A 1 142 ? 124.259 121.098 133.759 1.00 26.34  ? 198 ILE A N     1 
ATOM 1076 C CA    . ILE A 1 142 ? 124.046 119.715 134.170 1.00 26.34  ? 198 ILE A CA    1 
ATOM 1077 C C     . ILE A 1 142 ? 125.257 118.939 133.666 1.00 26.34  ? 198 ILE A C     1 
ATOM 1078 O O     . ILE A 1 142 ? 125.292 118.457 132.534 1.00 26.34  ? 198 ILE A O     1 
ATOM 1079 C CB    . ILE A 1 142 ? 122.732 119.162 133.631 1.00 26.34  ? 198 ILE A CB    1 
ATOM 1080 C CG1   . ILE A 1 142 ? 121.549 119.918 134.233 1.00 26.34  ? 198 ILE A CG1   1 
ATOM 1081 C CG2   . ILE A 1 142 ? 122.628 117.680 133.887 1.00 26.34  ? 198 ILE A CG2   1 
ATOM 1082 C CD1   . ILE A 1 142 ? 120.236 119.616 133.558 1.00 26.34  ? 198 ILE A CD1   1 
ATOM 1083 N N     . TYR A 1 143 ? 126.275 118.837 134.511 1.00 27.80  ? 199 TYR A N     1 
ATOM 1084 C CA    . TYR A 1 143 ? 127.489 118.138 134.122 1.00 27.80  ? 199 TYR A CA    1 
ATOM 1085 C C     . TYR A 1 143 ? 127.256 116.635 134.066 1.00 27.80  ? 199 TYR A C     1 
ATOM 1086 O O     . TYR A 1 143 ? 126.459 116.082 134.829 1.00 27.80  ? 199 TYR A O     1 
ATOM 1087 C CB    . TYR A 1 143 ? 128.618 118.448 135.094 1.00 27.80  ? 199 TYR A CB    1 
ATOM 1088 C CG    . TYR A 1 143 ? 129.225 119.818 134.935 1.00 27.80  ? 199 TYR A CG    1 
ATOM 1089 C CD1   . TYR A 1 143 ? 128.702 120.915 135.600 1.00 27.80  ? 199 TYR A CD1   1 
ATOM 1090 C CD2   . TYR A 1 143 ? 130.336 120.010 134.130 1.00 27.80  ? 199 TYR A CD2   1 
ATOM 1091 C CE1   . TYR A 1 143 ? 129.261 122.160 135.454 1.00 27.80  ? 199 TYR A CE1   1 
ATOM 1092 C CE2   . TYR A 1 143 ? 130.899 121.244 133.980 1.00 27.80  ? 199 TYR A CE2   1 
ATOM 1093 C CZ    . TYR A 1 143 ? 130.363 122.318 134.642 1.00 27.80  ? 199 TYR A CZ    1 
ATOM 1094 O OH    . TYR A 1 143 ? 130.932 123.560 134.491 1.00 27.80  ? 199 TYR A OH    1 
ATOM 1095 N N     . CYS A 1 144 ? 127.959 115.976 133.153 1.00 30.54  ? 200 CYS A N     1 
ATOM 1096 C CA    . CYS A 1 144 ? 127.898 114.532 133.005 1.00 30.54  ? 200 CYS A CA    1 
ATOM 1097 C C     . CYS A 1 144 ? 129.240 113.914 133.377 1.00 30.54  ? 200 CYS A C     1 
ATOM 1098 O O     . CYS A 1 144 ? 130.297 114.532 133.227 1.00 30.54  ? 200 CYS A O     1 
ATOM 1099 C CB    . CYS A 1 144 ? 127.505 114.157 131.577 1.00 30.54  ? 200 CYS A CB    1 
ATOM 1100 S SG    . CYS A 1 144 ? 125.811 114.588 131.159 1.00 30.54  ? 200 CYS A SG    1 
ATOM 1101 N N     . TYR A 1 145 ? 129.187 112.682 133.873 1.00 28.07  ? 201 TYR A N     1 
ATOM 1102 C CA    . TYR A 1 145 ? 130.337 112.051 134.502 1.00 28.07  ? 201 TYR A CA    1 
ATOM 1103 C C     . TYR A 1 145 ? 130.647 110.728 133.806 1.00 28.07  ? 201 TYR A C     1 
ATOM 1104 O O     . TYR A 1 145 ? 130.027 110.370 132.800 1.00 28.07  ? 201 TYR A O     1 
ATOM 1105 C CB    . TYR A 1 145 ? 130.104 111.874 136.006 1.00 28.07  ? 201 TYR A CB    1 
ATOM 1106 C CG    . TYR A 1 145 ? 128.721 111.401 136.371 1.00 28.07  ? 201 TYR A CG    1 
ATOM 1107 C CD1   . TYR A 1 145 ? 127.670 112.292 136.485 1.00 28.07  ? 201 TYR A CD1   1 
ATOM 1108 C CD2   . TYR A 1 145 ? 128.474 110.066 136.630 1.00 28.07  ? 201 TYR A CD2   1 
ATOM 1109 C CE1   . TYR A 1 145 ? 126.414 111.866 136.819 1.00 28.07  ? 201 TYR A CE1   1 
ATOM 1110 C CE2   . TYR A 1 145 ? 127.217 109.635 136.973 1.00 28.07  ? 201 TYR A CE2   1 
ATOM 1111 C CZ    . TYR A 1 145 ? 126.191 110.535 137.067 1.00 28.07  ? 201 TYR A CZ    1 
ATOM 1112 O OH    . TYR A 1 145 ? 124.938 110.086 137.409 1.00 28.07  ? 201 TYR A OH    1 
ATOM 1113 N N     . GLN A 1 146 ? 131.633 110.003 134.345 1.00 33.73  ? 202 GLN A N     1 
ATOM 1114 C CA    . GLN A 1 146 ? 132.206 108.866 133.629 1.00 33.73  ? 202 GLN A CA    1 
ATOM 1115 C C     . GLN A 1 146 ? 131.194 107.744 133.445 1.00 33.73  ? 202 GLN A C     1 
ATOM 1116 O O     . GLN A 1 146 ? 131.049 107.203 132.344 1.00 33.73  ? 202 GLN A O     1 
ATOM 1117 C CB    . GLN A 1 146 ? 133.437 108.344 134.364 1.00 33.73  ? 202 GLN A CB    1 
ATOM 1118 C CG    . GLN A 1 146 ? 134.162 107.233 133.621 1.00 33.73  ? 202 GLN A CG    1 
ATOM 1119 C CD    . GLN A 1 146 ? 135.212 106.549 134.471 1.00 33.73  ? 202 GLN A CD    1 
ATOM 1120 O OE1   . GLN A 1 146 ? 135.321 106.808 135.668 1.00 33.73  ? 202 GLN A OE1   1 
ATOM 1121 N NE2   . GLN A 1 146 ? 135.996 105.672 133.854 1.00 33.73  ? 202 GLN A NE2   1 
ATOM 1122 N N     . GLN A 1 147 ? 130.493 107.364 134.513 1.00 31.15  ? 203 GLN A N     1 
ATOM 1123 C CA    . GLN A 1 147 ? 129.633 106.193 134.402 1.00 31.15  ? 203 GLN A CA    1 
ATOM 1124 C C     . GLN A 1 147 ? 128.386 106.469 133.585 1.00 31.15  ? 203 GLN A C     1 
ATOM 1125 O O     . GLN A 1 147 ? 127.718 105.518 133.166 1.00 31.15  ? 203 GLN A O     1 
ATOM 1126 C CB    . GLN A 1 147 ? 129.217 105.669 135.774 1.00 31.15  ? 203 GLN A CB    1 
ATOM 1127 C CG    . GLN A 1 147 ? 128.171 106.507 136.449 1.00 31.15  ? 203 GLN A CG    1 
ATOM 1128 C CD    . GLN A 1 147 ? 127.788 105.973 137.802 1.00 31.15  ? 203 GLN A CD    1 
ATOM 1129 O OE1   . GLN A 1 147 ? 128.302 104.952 138.242 1.00 31.15  ? 203 GLN A OE1   1 
ATOM 1130 N NE2   . GLN A 1 147 ? 126.862 106.651 138.466 1.00 31.15  ? 203 GLN A NE2   1 
ATOM 1131 N N     . VAL A 1 148 ? 128.098 107.754 133.344 1.00 30.19  ? 204 VAL A N     1 
ATOM 1132 C CA    . VAL A 1 148 ? 126.982 108.141 132.475 1.00 30.19  ? 204 VAL A CA    1 
ATOM 1133 C C     . VAL A 1 148 ? 127.606 108.960 131.360 1.00 30.19  ? 204 VAL A C     1 
ATOM 1134 O O     . VAL A 1 148 ? 127.702 110.184 131.461 1.00 30.19  ? 204 VAL A O     1 
ATOM 1135 C CB    . VAL A 1 148 ? 125.888 108.919 133.193 1.00 30.19  ? 204 VAL A CB    1 
ATOM 1136 C CG1   . VAL A 1 148 ? 124.799 109.191 132.192 1.00 30.19  ? 204 VAL A CG1   1 
ATOM 1137 C CG2   . VAL A 1 148 ? 125.318 108.095 134.336 1.00 30.19  ? 204 VAL A CG2   1 
ATOM 1138 N N     . SER A 1 149 ? 127.982 108.313 130.275 1.00 31.99  ? 205 SER A N     1 
ATOM 1139 C CA    . SER A 1 149 ? 128.719 108.924 129.188 1.00 31.99  ? 205 SER A CA    1 
ATOM 1140 C C     . SER A 1 149 ? 127.920 108.807 127.901 1.00 31.99  ? 205 SER A C     1 
ATOM 1141 O O     . SER A 1 149 ? 126.958 108.033 127.829 1.00 31.99  ? 205 SER A O     1 
ATOM 1142 C CB    . SER A 1 149 ? 130.086 108.245 129.023 1.00 31.99  ? 205 SER A CB    1 
ATOM 1143 O OG    . SER A 1 149 ? 130.841 108.342 130.214 1.00 31.99  ? 205 SER A OG    1 
ATOM 1144 N N     . PRO A 1 150 ? 128.270 109.577 126.867 1.00 31.61  ? 206 PRO A N     1 
ATOM 1145 C CA    . PRO A 1 150 ? 127.596 109.405 125.575 1.00 31.61  ? 206 PRO A CA    1 
ATOM 1146 C C     . PRO A 1 150 ? 127.817 108.017 124.993 1.00 31.61  ? 206 PRO A C     1 
ATOM 1147 O O     . PRO A 1 150 ? 128.934 107.651 124.616 1.00 31.61  ? 206 PRO A O     1 
ATOM 1148 C CB    . PRO A 1 150 ? 128.223 110.495 124.695 1.00 31.61  ? 206 PRO A CB    1 
ATOM 1149 C CG    . PRO A 1 150 ? 129.468 110.911 125.401 1.00 31.61  ? 206 PRO A CG    1 
ATOM 1150 C CD    . PRO A 1 150 ? 129.200 110.719 126.853 1.00 31.61  ? 206 PRO A CD    1 
ATOM 1151 N N     . VAL A 1 151 ? 126.743 107.239 124.930 1.00 31.44  ? 207 VAL A N     1 
ATOM 1152 C CA    . VAL A 1 151 ? 126.744 105.912 124.325 1.00 31.44  ? 207 VAL A CA    1 
ATOM 1153 C C     . VAL A 1 151 ? 126.023 106.031 122.988 1.00 31.44  ? 207 VAL A C     1 
ATOM 1154 O O     . VAL A 1 151 ? 125.109 106.859 122.859 1.00 31.44  ? 207 VAL A O     1 
ATOM 1155 C CB    . VAL A 1 151 ? 126.058 104.883 125.239 1.00 31.44  ? 207 VAL A CB    1 
ATOM 1156 C CG1   . VAL A 1 151 ? 126.334 103.461 124.777 1.00 31.44  ? 207 VAL A CG1   1 
ATOM 1157 C CG2   . VAL A 1 151 ? 126.502 105.072 126.681 1.00 31.44  ? 207 VAL A CG2   1 
ATOM 1158 N N     . PRO A 1 152 ? 126.387 105.245 121.971 1.00 30.02  ? 208 PRO A N     1 
ATOM 1159 C CA    . PRO A 1 152 ? 125.592 105.237 120.736 1.00 30.02  ? 208 PRO A CA    1 
ATOM 1160 C C     . PRO A 1 152 ? 124.183 104.733 120.980 1.00 30.02  ? 208 PRO A C     1 
ATOM 1161 O O     . PRO A 1 152 ? 123.819 104.412 122.116 1.00 30.02  ? 208 PRO A O     1 
ATOM 1162 C CB    . PRO A 1 152 ? 126.379 104.294 119.820 1.00 30.02  ? 208 PRO A CB    1 
ATOM 1163 C CG    . PRO A 1 152 ? 127.763 104.374 120.317 1.00 30.02  ? 208 PRO A CG    1 
ATOM 1164 C CD    . PRO A 1 152 ? 127.671 104.545 121.798 1.00 30.02  ? 208 PRO A CD    1 
ATOM 1165 N N     . TYR A 1 153 ? 123.377 104.664 119.928 1.00 29.15  ? 209 TYR A N     1 
ATOM 1166 C CA    . TYR A 1 153 ? 121.985 104.261 120.040 1.00 29.15  ? 209 TYR A CA    1 
ATOM 1167 C C     . TYR A 1 153 ? 121.810 102.841 119.520 1.00 29.15  ? 209 TYR A C     1 
ATOM 1168 O O     . TYR A 1 153 ? 122.190 102.538 118.385 1.00 29.15  ? 209 TYR A O     1 
ATOM 1169 C CB    . TYR A 1 153 ? 121.085 105.224 119.272 1.00 29.15  ? 209 TYR A CB    1 
ATOM 1170 C CG    . TYR A 1 153 ? 119.663 105.249 119.757 1.00 29.15  ? 209 TYR A CG    1 
ATOM 1171 C CD1   . TYR A 1 153 ? 119.363 105.606 121.053 1.00 29.15  ? 209 TYR A CD1   1 
ATOM 1172 C CD2   . TYR A 1 153 ? 118.619 104.937 118.910 1.00 29.15  ? 209 TYR A CD2   1 
ATOM 1173 C CE1   . TYR A 1 153 ? 118.069 105.636 121.496 1.00 29.15  ? 209 TYR A CE1   1 
ATOM 1174 C CE2   . TYR A 1 153 ? 117.323 104.968 119.343 1.00 29.15  ? 209 TYR A CE2   1 
ATOM 1175 C CZ    . TYR A 1 153 ? 117.051 105.319 120.635 1.00 29.15  ? 209 TYR A CZ    1 
ATOM 1176 O OH    . TYR A 1 153 ? 115.749 105.348 121.073 1.00 29.15  ? 209 TYR A OH    1 
ATOM 1177 N N     . ASN A 1 154 ? 121.236 101.982 120.354 1.00 33.09  ? 210 ASN A N     1 
ATOM 1178 C CA    . ASN A 1 154 ? 120.899 100.611 119.979 1.00 33.09  ? 210 ASN A CA    1 
ATOM 1179 C C     . ASN A 1 154 ? 119.449 100.362 120.362 1.00 33.09  ? 210 ASN A C     1 
ATOM 1180 O O     . ASN A 1 154 ? 119.153 100.194 121.563 1.00 33.09  ? 210 ASN A O     1 
ATOM 1181 C CB    . ASN A 1 154 ? 121.824 99.608  120.664 1.00 33.09  ? 210 ASN A CB    1 
ATOM 1182 C CG    . ASN A 1 154 ? 123.292 99.903  120.419 1.00 33.09  ? 210 ASN A CG    1 
ATOM 1183 O OD1   . ASN A 1 154 ? 123.668 100.410 119.364 1.00 33.09  ? 210 ASN A OD1   1 
ATOM 1184 N ND2   . ASN A 1 154 ? 124.131 99.583  121.398 1.00 33.09  ? 210 ASN A ND2   1 
ATOM 1185 N N     . PRO A 1 155 ? 118.526 100.310 119.400 1.00 34.96  ? 211 PRO A N     1 
ATOM 1186 C CA    . PRO A 1 155 ? 117.098 100.218 119.751 1.00 34.96  ? 211 PRO A CA    1 
ATOM 1187 C C     . PRO A 1 155 ? 116.735 98.987  120.562 1.00 34.96  ? 211 PRO A C     1 
ATOM 1188 O O     . PRO A 1 155 ? 115.637 98.943  121.131 1.00 34.96  ? 211 PRO A O     1 
ATOM 1189 C CB    . PRO A 1 155 ? 116.401 100.211 118.383 1.00 34.96  ? 211 PRO A CB    1 
ATOM 1190 C CG    . PRO A 1 155 ? 117.382 100.845 117.454 1.00 34.96  ? 211 PRO A CG    1 
ATOM 1191 C CD    . PRO A 1 155 ? 118.734 100.438 117.950 1.00 34.96  ? 211 PRO A CD    1 
ATOM 1192 N N     . ALA A 1 156 ? 117.604 97.980  120.619 1.00 35.17  ? 212 ALA A N     1 
ATOM 1193 C CA    . ALA A 1 156 ? 117.327 96.817  121.454 1.00 35.17  ? 212 ALA A CA    1 
ATOM 1194 C C     . ALA A 1 156 ? 117.391 97.173  122.934 1.00 35.17  ? 212 ALA A C     1 
ATOM 1195 O O     . ALA A 1 156 ? 116.607 96.660  123.741 1.00 35.17  ? 212 ALA A O     1 
ATOM 1196 C CB    . ALA A 1 156 ? 118.307 95.690  121.125 1.00 35.17  ? 212 ALA A CB    1 
ATOM 1197 N N     . LYS A 1 157 ? 118.320 98.052  123.312 1.00 34.83  ? 213 LYS A N     1 
ATOM 1198 C CA    . LYS A 1 157 ? 118.556 98.357  124.718 1.00 34.83  ? 213 LYS A CA    1 
ATOM 1199 C C     . LYS A 1 157 ? 117.808 99.605  125.180 1.00 34.83  ? 213 LYS A C     1 
ATOM 1200 O O     . LYS A 1 157 ? 117.048 99.553  126.151 1.00 34.83  ? 213 LYS A O     1 
ATOM 1201 C CB    . LYS A 1 157 ? 120.059 98.515  124.966 1.00 34.83  ? 213 LYS A CB    1 
ATOM 1202 C CG    . LYS A 1 157 ? 120.482 98.311  126.413 1.00 34.83  ? 213 LYS A CG    1 
ATOM 1203 C CD    . LYS A 1 157 ? 120.641 99.635  127.143 1.00 34.83  ? 213 LYS A CD    1 
ATOM 1204 C CE    . LYS A 1 157 ? 121.106 99.422  128.573 1.00 34.83  ? 213 LYS A CE    1 
ATOM 1205 N NZ    . LYS A 1 157 ? 121.223 100.707 129.317 1.00 34.83  ? 213 LYS A NZ    1 
ATOM 1206 N N     . HIS A 1 158 ? 117.979 100.704 124.451 1.00 33.86  ? 214 HIS A N     1 
ATOM 1207 C CA    . HIS A 1 158 ? 117.328 101.967 124.804 1.00 33.86  ? 214 HIS A CA    1 
ATOM 1208 C C     . HIS A 1 158 ? 115.825 101.967 124.508 1.00 33.86  ? 214 HIS A C     1 
ATOM 1209 O O     . HIS A 1 158 ? 115.351 101.152 123.714 1.00 33.86  ? 214 HIS A O     1 
ATOM 1210 C CB    . HIS A 1 158 ? 118.030 103.108 124.064 1.00 33.86  ? 214 HIS A CB    1 
ATOM 1211 C CG    . HIS A 1 158 ? 119.516 103.112 124.243 1.00 33.86  ? 214 HIS A CG    1 
ATOM 1212 N ND1   . HIS A 1 158 ? 120.119 103.421 125.443 1.00 33.86  ? 214 HIS A ND1   1 
ATOM 1213 C CD2   . HIS A 1 158 ? 120.520 102.841 123.377 1.00 33.86  ? 214 HIS A CD2   1 
ATOM 1214 C CE1   . HIS A 1 158 ? 121.431 103.339 125.308 1.00 33.86  ? 214 HIS A CE1   1 
ATOM 1215 N NE2   . HIS A 1 158 ? 121.700 102.990 124.063 1.00 33.86  ? 214 HIS A NE2   1 
ATOM 1216 N N     . PRO A 1 159 ? 115.067 102.885 125.137 1.00 33.59  ? 215 PRO A N     1 
ATOM 1217 C CA    . PRO A 1 159 ? 113.607 102.917 124.952 1.00 33.59  ? 215 PRO A CA    1 
ATOM 1218 C C     . PRO A 1 159 ? 113.138 103.237 123.536 1.00 33.59  ? 215 PRO A C     1 
ATOM 1219 O O     . PRO A 1 159 ? 113.788 104.013 122.834 1.00 33.59  ? 215 PRO A O     1 
ATOM 1220 C CB    . PRO A 1 159 ? 113.153 104.027 125.913 1.00 33.59  ? 215 PRO A CB    1 
ATOM 1221 C CG    . PRO A 1 159 ? 114.381 104.822 126.210 1.00 33.59  ? 215 PRO A CG    1 
ATOM 1222 C CD    . PRO A 1 159 ? 115.495 103.823 126.190 1.00 33.59  ? 215 PRO A CD    1 
ATOM 1223 N N     . ALA A 1 160 ? 112.022 102.642 123.122 1.00 34.53  ? 216 ALA A N     1 
ATOM 1224 C CA    . ALA A 1 160 ? 111.485 102.872 121.778 1.00 34.53  ? 216 ALA A CA    1 
ATOM 1225 C C     . ALA A 1 160 ? 111.259 104.343 121.457 1.00 34.53  ? 216 ALA A C     1 
ATOM 1226 O O     . ALA A 1 160 ? 110.709 105.076 122.282 1.00 34.53  ? 216 ALA A O     1 
ATOM 1227 C CB    . ALA A 1 160 ? 110.197 102.086 121.584 1.00 34.53  ? 216 ALA A CB    1 
ATOM 1228 N N     . LEU A 1 161 ? 111.649 104.767 120.257 1.00 36.23  ? 217 LEU A N     1 
ATOM 1229 C CA    . LEU A 1 161 ? 111.525 106.161 119.857 1.00 36.23  ? 217 LEU A CA    1 
ATOM 1230 C C     . LEU A 1 161 ? 111.753 106.251 118.353 1.00 36.23  ? 217 LEU A C     1 
ATOM 1231 O O     . LEU A 1 161 ? 112.530 105.457 117.806 1.00 36.23  ? 217 LEU A O     1 
ATOM 1232 C CB    . LEU A 1 161 ? 112.538 107.022 120.613 1.00 36.23  ? 217 LEU A CB    1 
ATOM 1233 C CG    . LEU A 1 161 ? 112.321 108.532 120.678 1.00 36.23  ? 217 LEU A CG    1 
ATOM 1234 C CD1   . LEU A 1 161 ? 111.078 108.866 121.491 1.00 36.23  ? 217 LEU A CD1   1 
ATOM 1235 C CD2   . LEU A 1 161 ? 113.547 109.204 121.262 1.00 36.23  ? 217 LEU A CD2   1 
ATOM 1236 N N     . PRO A 1 162 ? 111.109 107.185 117.640 1.00 38.74  ? 218 PRO A N     1 
ATOM 1237 C CA    . PRO A 1 162 ? 111.379 107.293 116.200 1.00 38.74  ? 218 PRO A CA    1 
ATOM 1238 C C     . PRO A 1 162 ? 112.767 107.851 115.924 1.00 38.74  ? 218 PRO A C     1 
ATOM 1239 O O     . PRO A 1 162 ? 113.003 109.060 116.003 1.00 38.74  ? 218 PRO A O     1 
ATOM 1240 C CB    . PRO A 1 162 ? 110.277 108.235 115.699 1.00 38.74  ? 218 PRO A CB    1 
ATOM 1241 C CG    . PRO A 1 162 ? 109.819 108.976 116.907 1.00 38.74  ? 218 PRO A CG    1 
ATOM 1242 C CD    . PRO A 1 162 ? 109.987 108.041 118.062 1.00 38.74  ? 218 PRO A CD    1 
ATOM 1243 N N     . PHE A 1 163 ? 113.677 106.953 115.565 1.00 35.88  ? 219 PHE A N     1 
ATOM 1244 C CA    . PHE A 1 163 ? 115.070 107.253 115.257 1.00 35.88  ? 219 PHE A CA    1 
ATOM 1245 C C     . PHE A 1 163 ? 115.627 106.076 114.468 1.00 35.88  ? 219 PHE A C     1 
ATOM 1246 O O     . PHE A 1 163 ? 114.912 105.111 114.179 1.00 35.88  ? 219 PHE A O     1 
ATOM 1247 C CB    . PHE A 1 163 ? 115.888 107.515 116.528 1.00 35.88  ? 219 PHE A CB    1 
ATOM 1248 C CG    . PHE A 1 163 ? 116.043 108.970 116.868 1.00 35.88  ? 219 PHE A CG    1 
ATOM 1249 C CD1   . PHE A 1 163 ? 116.958 109.754 116.187 1.00 35.88  ? 219 PHE A CD1   1 
ATOM 1250 C CD2   . PHE A 1 163 ? 115.303 109.545 117.886 1.00 35.88  ? 219 PHE A CD2   1 
ATOM 1251 C CE1   . PHE A 1 163 ? 117.116 111.086 116.495 1.00 35.88  ? 219 PHE A CE1   1 
ATOM 1252 C CE2   . PHE A 1 163 ? 115.457 110.880 118.199 1.00 35.88  ? 219 PHE A CE2   1 
ATOM 1253 C CZ    . PHE A 1 163 ? 116.366 111.651 117.503 1.00 35.88  ? 219 PHE A CZ    1 
ATOM 1254 N N     . SER A 1 164 ? 116.913 106.149 114.119 1.00 35.41  ? 220 SER A N     1 
ATOM 1255 C CA    . SER A 1 164 ? 117.552 105.055 113.393 1.00 35.41  ? 220 SER A CA    1 
ATOM 1256 C C     . SER A 1 164 ? 119.053 105.111 113.673 1.00 35.41  ? 220 SER A C     1 
ATOM 1257 O O     . SER A 1 164 ? 119.769 105.901 113.053 1.00 35.41  ? 220 SER A O     1 
ATOM 1258 C CB    . SER A 1 164 ? 117.261 105.143 111.904 1.00 35.41  ? 220 SER A CB    1 
ATOM 1259 O OG    . SER A 1 164 ? 118.014 104.186 111.179 1.00 35.41  ? 220 SER A OG    1 
ATOM 1260 N N     . GLY A 1 165 ? 119.525 104.289 114.609 1.00 33.82  ? 221 GLY A N     1 
ATOM 1261 C CA    . GLY A 1 165 ? 120.931 104.316 114.988 1.00 33.82  ? 221 GLY A CA    1 
ATOM 1262 C C     . GLY A 1 165 ? 121.833 103.342 114.263 1.00 33.82  ? 221 GLY A C     1 
ATOM 1263 O O     . GLY A 1 165 ? 121.527 102.154 114.174 1.00 33.82  ? 221 GLY A O     1 
ATOM 1264 N N     . VAL A 1 166 ? 122.951 103.838 113.745 1.00 34.60  ? 222 VAL A N     1 
ATOM 1265 C CA    . VAL A 1 166 ? 123.908 102.985 113.039 1.00 34.60  ? 222 VAL A CA    1 
ATOM 1266 C C     . VAL A 1 166 ? 124.723 102.086 113.964 1.00 34.60  ? 222 VAL A C     1 
ATOM 1267 O O     . VAL A 1 166 ? 124.847 102.363 115.158 1.00 34.60  ? 222 VAL A O     1 
ATOM 1268 C CB    . VAL A 1 166 ? 124.865 103.819 112.170 1.00 34.60  ? 222 VAL A CB    1 
ATOM 1269 C CG1   . VAL A 1 166 ? 124.150 104.317 110.924 1.00 34.60  ? 222 VAL A CG1   1 
ATOM 1270 C CG2   . VAL A 1 166 ? 125.418 104.981 112.973 1.00 34.60  ? 222 VAL A CG2   1 
ATOM 1271 N N     . ASP A 1 167 ? 125.273 101.008 113.417 1.00 36.47  ? 223 ASP A N     1 
ATOM 1272 C CA    . ASP A 1 167 ? 126.074 100.079 114.215 1.00 36.47  ? 223 ASP A CA    1 
ATOM 1273 C C     . ASP A 1 167 ? 127.344 100.719 114.763 1.00 36.47  ? 223 ASP A C     1 
ATOM 1274 O O     . ASP A 1 167 ? 127.962 101.540 114.084 1.00 36.47  ? 223 ASP A O     1 
ATOM 1275 C CB    . ASP A 1 167 ? 126.437 98.850  113.377 1.00 36.47  ? 223 ASP A CB    1 
ATOM 1276 C CG    . ASP A 1 167 ? 125.223 98.034  112.984 1.00 36.47  ? 223 ASP A CG    1 
ATOM 1277 O OD1   . ASP A 1 167 ? 125.378 97.088  112.184 1.00 36.47  ? 223 ASP A OD1   1 
ATOM 1278 O OD2   . ASP A 1 167 ? 124.114 98.337  113.472 1.00 36.47  ? 223 ASP A OD2   1 
ATOM 1279 N N     . PRO A 1 168 ? 127.734 100.353 115.998 1.00 38.20  ? 224 PRO A N     1 
ATOM 1280 C CA    . PRO A 1 168 ? 128.952 100.897 116.614 1.00 38.20  ? 224 PRO A CA    1 
ATOM 1281 C C     . PRO A 1 168 ? 130.116 101.004 115.641 1.00 38.20  ? 224 PRO A C     1 
ATOM 1282 O O     . PRO A 1 168 ? 130.695 102.078 115.551 1.00 38.20  ? 224 PRO A O     1 
ATOM 1283 C CB    . PRO A 1 168 ? 129.267 99.872  117.699 1.00 38.20  ? 224 PRO A CB    1 
ATOM 1284 C CG    . PRO A 1 168 ? 127.927 99.355  118.109 1.00 38.20  ? 224 PRO A CG    1 
ATOM 1285 C CD    . PRO A 1 168 ? 127.013 99.452  116.914 1.00 38.20  ? 224 PRO A CD    1 
ATOM 1286 N N     . GLY A 1 169 ? 130.464 99.926  114.943 1.00 38.30  ? 225 GLY A N     1 
ATOM 1287 C CA    . GLY A 1 169 ? 131.508 99.991  113.938 1.00 38.30  ? 225 GLY A CA    1 
ATOM 1288 C C     . GLY A 1 169 ? 131.035 99.879  112.502 1.00 38.30  ? 225 GLY A C     1 
ATOM 1289 O O     . GLY A 1 169 ? 130.607 98.811  112.057 1.00 38.30  ? 225 GLY A O     1 
ATOM 1290 N N     . ALA A 1 170 ? 131.141 100.985 111.767 1.00 36.26  ? 226 ALA A N     1 
ATOM 1291 C CA    . ALA A 1 170 ? 130.953 101.092 110.326 1.00 36.26  ? 226 ALA A CA    1 
ATOM 1292 C C     . ALA A 1 170 ? 131.361 102.496 109.897 1.00 36.26  ? 226 ALA A C     1 
ATOM 1293 O O     . ALA A 1 170 ? 130.959 103.472 110.543 1.00 36.26  ? 226 ALA A O     1 
ATOM 1294 C CB    . ALA A 1 170 ? 129.504 100.813 109.927 1.00 36.26  ? 226 ALA A CB    1 
ATOM 1295 N N     . PRO A 1 171 ? 132.145 102.652 108.831 1.00 36.01  ? 227 PRO A N     1 
ATOM 1296 C CA    . PRO A 1 171 ? 132.472 104.005 108.356 1.00 36.01  ? 227 PRO A CA    1 
ATOM 1297 C C     . PRO A 1 171 ? 131.202 104.762 108.001 1.00 36.01  ? 227 PRO A C     1 
ATOM 1298 O O     . PRO A 1 171 ? 130.401 104.315 107.176 1.00 36.01  ? 227 PRO A O     1 
ATOM 1299 C CB    . PRO A 1 171 ? 133.353 103.748 107.131 1.00 36.01  ? 227 PRO A CB    1 
ATOM 1300 C CG    . PRO A 1 171 ? 133.941 102.410 107.361 1.00 36.01  ? 227 PRO A CG    1 
ATOM 1301 C CD    . PRO A 1 171 ? 132.945 101.616 108.155 1.00 36.01  ? 227 PRO A CD    1 
ATOM 1302 N N     . LEU A 1 172 ? 131.014 105.915 108.643 1.00 33.28  ? 228 LEU A N     1 
ATOM 1303 C CA    . LEU A 1 172 ? 129.754 106.629 108.525 1.00 33.28  ? 228 LEU A CA    1 
ATOM 1304 C C     . LEU A 1 172 ? 129.531 107.118 107.095 1.00 33.28  ? 228 LEU A C     1 
ATOM 1305 O O     . LEU A 1 172 ? 130.489 107.380 106.361 1.00 33.28  ? 228 LEU A O     1 
ATOM 1306 C CB    . LEU A 1 172 ? 129.704 107.810 109.489 1.00 33.28  ? 228 LEU A CB    1 
ATOM 1307 C CG    . LEU A 1 172 ? 129.410 107.457 110.940 1.00 33.28  ? 228 LEU A CG    1 
ATOM 1308 C CD1   . LEU A 1 172 ? 129.692 108.643 111.835 1.00 33.28  ? 228 LEU A CD1   1 
ATOM 1309 C CD2   . LEU A 1 172 ? 127.967 107.007 111.073 1.00 33.28  ? 228 LEU A CD2   1 
ATOM 1310 N N     . PRO A 1 173 ? 128.272 107.240 106.678 1.00 33.29  ? 229 PRO A N     1 
ATOM 1311 C CA    . PRO A 1 173 ? 127.981 107.669 105.306 1.00 33.29  ? 229 PRO A CA    1 
ATOM 1312 C C     . PRO A 1 173 ? 128.622 109.011 104.991 1.00 33.29  ? 229 PRO A C     1 
ATOM 1313 O O     . PRO A 1 173 ? 128.664 109.915 105.830 1.00 33.29  ? 229 PRO A O     1 
ATOM 1314 C CB    . PRO A 1 173 ? 126.451 107.762 105.274 1.00 33.29  ? 229 PRO A CB    1 
ATOM 1315 C CG    . PRO A 1 173 ? 125.952 107.154 106.533 1.00 33.29  ? 229 PRO A CG    1 
ATOM 1316 C CD    . PRO A 1 173 ? 127.089 106.706 107.371 1.00 33.29  ? 229 PRO A CD    1 
ATOM 1317 N N     . LEU A 1 174 ? 129.131 109.136 103.771 1.00 32.90  ? 230 LEU A N     1 
ATOM 1318 C CA    . LEU A 1 174 ? 129.745 110.377 103.331 1.00 32.90  ? 230 LEU A CA    1 
ATOM 1319 C C     . LEU A 1 174 ? 128.744 111.202 102.530 1.00 32.90  ? 230 LEU A C     1 
ATOM 1320 O O     . LEU A 1 174 ? 127.547 110.918 102.539 1.00 32.90  ? 230 LEU A O     1 
ATOM 1321 C CB    . LEU A 1 174 ? 130.994 110.096 102.497 1.00 32.90  ? 230 LEU A CB    1 
ATOM 1322 C CG    . LEU A 1 174 ? 131.945 111.277 102.300 1.00 32.90  ? 230 LEU A CG    1 
ATOM 1323 C CD1   . LEU A 1 174 ? 132.600 111.643 103.614 1.00 32.90  ? 230 LEU A CD1   1 
ATOM 1324 C CD2   . LEU A 1 174 ? 132.991 110.954 101.253 1.00 32.90  ? 230 LEU A CD2   1 
ATOM 1325 N N     . PRO A 1 187 ? 115.468 117.236 94.661  1.00 28.05  ? 243 PRO A N     1 
ATOM 1326 C CA    . PRO A 1 187 ? 116.334 117.660 95.763  1.00 28.05  ? 243 PRO A CA    1 
ATOM 1327 C C     . PRO A 1 187 ? 117.806 117.709 95.382  1.00 28.05  ? 243 PRO A C     1 
ATOM 1328 O O     . PRO A 1 187 ? 118.357 116.709 94.935  1.00 28.05  ? 243 PRO A O     1 
ATOM 1329 C CB    . PRO A 1 187 ? 116.075 116.595 96.818  1.00 28.05  ? 243 PRO A CB    1 
ATOM 1330 C CG    . PRO A 1 187 ? 114.651 116.241 96.616  1.00 28.05  ? 243 PRO A CG    1 
ATOM 1331 C CD    . PRO A 1 187 ? 114.373 116.372 95.136  1.00 28.05  ? 243 PRO A CD    1 
ATOM 1332 N N     . GLY A 1 188 ? 118.429 118.868 95.565  1.00 29.43  ? 244 GLY A N     1 
ATOM 1333 C CA    . GLY A 1 188 ? 119.828 119.036 95.211  1.00 29.43  ? 244 GLY A CA    1 
ATOM 1334 C C     . GLY A 1 188 ? 120.094 118.870 93.732  1.00 29.43  ? 244 GLY A C     1 
ATOM 1335 O O     . GLY A 1 188 ? 121.066 118.209 93.347  1.00 29.43  ? 244 GLY A O     1 
ATOM 1336 N N     . TYR A 1 189 ? 119.244 119.459 92.887  1.00 28.24  ? 245 TYR A N     1 
ATOM 1337 C CA    . TYR A 1 189 ? 119.362 119.233 91.452  1.00 28.24  ? 245 TYR A CA    1 
ATOM 1338 C C     . TYR A 1 189 ? 120.580 119.926 90.851  1.00 28.24  ? 245 TYR A C     1 
ATOM 1339 O O     . TYR A 1 189 ? 121.088 119.479 89.817  1.00 28.24  ? 245 TYR A O     1 
ATOM 1340 C CB    . TYR A 1 189 ? 118.088 119.689 90.745  1.00 28.24  ? 245 TYR A CB    1 
ATOM 1341 C CG    . TYR A 1 189 ? 118.208 119.669 89.239  1.00 28.24  ? 245 TYR A CG    1 
ATOM 1342 C CD1   . TYR A 1 189 ? 118.534 118.503 88.565  1.00 28.24  ? 245 TYR A CD1   1 
ATOM 1343 C CD2   . TYR A 1 189 ? 118.006 120.817 88.494  1.00 28.24  ? 245 TYR A CD2   1 
ATOM 1344 C CE1   . TYR A 1 189 ? 118.653 118.481 87.206  1.00 28.24  ? 245 TYR A CE1   1 
ATOM 1345 C CE2   . TYR A 1 189 ? 118.121 120.802 87.127  1.00 28.24  ? 245 TYR A CE2   1 
ATOM 1346 C CZ    . TYR A 1 189 ? 118.444 119.630 86.489  1.00 28.24  ? 245 TYR A CZ    1 
ATOM 1347 O OH    . TYR A 1 189 ? 118.559 119.609 85.118  1.00 28.24  ? 245 TYR A OH    1 
ATOM 1348 N N     . VAL A 1 190 ? 121.057 121.000 91.478  1.00 27.39  ? 246 VAL A N     1 
ATOM 1349 C CA    . VAL A 1 190 ? 122.121 121.872 90.970  1.00 27.39  ? 246 VAL A CA    1 
ATOM 1350 C C     . VAL A 1 190 ? 121.901 122.170 89.487  1.00 27.39  ? 246 VAL A C     1 
ATOM 1351 O O     . VAL A 1 190 ? 122.583 121.611 88.617  1.00 27.39  ? 246 VAL A O     1 
ATOM 1352 C CB    . VAL A 1 190 ? 123.524 121.325 91.299  1.00 27.39  ? 246 VAL A CB    1 
ATOM 1353 C CG1   . VAL A 1 190 ? 123.872 119.992 90.628  1.00 27.39  ? 246 VAL A CG1   1 
ATOM 1354 C CG2   . VAL A 1 190 ? 124.572 122.376 90.986  1.00 27.39  ? 246 VAL A CG2   1 
ATOM 1355 N N     . PRO A 1 191 ? 120.946 123.046 89.166  1.00 32.52  ? 247 PRO A N     1 
ATOM 1356 C CA    . PRO A 1 191 ? 120.504 123.225 87.774  1.00 32.52  ? 247 PRO A CA    1 
ATOM 1357 C C     . PRO A 1 191 ? 121.616 123.678 86.839  1.00 32.52  ? 247 PRO A C     1 
ATOM 1358 O O     . PRO A 1 191 ? 122.671 124.155 87.258  1.00 32.52  ? 247 PRO A O     1 
ATOM 1359 C CB    . PRO A 1 191 ? 119.422 124.302 87.891  1.00 32.52  ? 247 PRO A CB    1 
ATOM 1360 C CG    . PRO A 1 191 ? 119.836 125.077 89.096  1.00 32.52  ? 247 PRO A CG    1 
ATOM 1361 C CD    . PRO A 1 191 ? 120.316 124.031 90.059  1.00 32.52  ? 247 PRO A CD    1 
ATOM 1362 N N     . GLU A 1 192 ? 121.338 123.542 85.540  1.00 33.13  ? 248 GLU A N     1 
ATOM 1363 C CA    . GLU A 1 192 ? 122.385 123.653 84.530  1.00 33.13  ? 248 GLU A CA    1 
ATOM 1364 C C     . GLU A 1 192 ? 123.022 125.035 84.524  1.00 33.13  ? 248 GLU A C     1 
ATOM 1365 O O     . GLU A 1 192 ? 124.227 125.167 84.283  1.00 33.13  ? 248 GLU A O     1 
ATOM 1366 C CB    . GLU A 1 192 ? 121.822 123.312 83.155  1.00 33.13  ? 248 GLU A CB    1 
ATOM 1367 C CG    . GLU A 1 192 ? 122.885 123.150 82.086  1.00 33.13  ? 248 GLU A CG    1 
ATOM 1368 C CD    . GLU A 1 192 ? 122.304 122.774 80.737  1.00 33.13  ? 248 GLU A CD    1 
ATOM 1369 O OE1   . GLU A 1 192 ? 121.080 122.537 80.661  1.00 33.13  ? 248 GLU A OE1   1 
ATOM 1370 O OE2   . GLU A 1 192 ? 123.072 122.717 79.754  1.00 33.13  ? 248 GLU A OE2   1 
ATOM 1371 N N     . TRP A 1 193 ? 122.238 126.079 84.787  1.00 34.61  ? 249 TRP A N     1 
ATOM 1372 C CA    . TRP A 1 193 ? 122.810 127.419 84.810  1.00 34.61  ? 249 TRP A CA    1 
ATOM 1373 C C     . TRP A 1 193 ? 123.609 127.673 86.081  1.00 34.61  ? 249 TRP A C     1 
ATOM 1374 O O     . TRP A 1 193 ? 124.267 128.715 86.187  1.00 34.61  ? 249 TRP A O     1 
ATOM 1375 C CB    . TRP A 1 193 ? 121.710 128.468 84.657  1.00 34.61  ? 249 TRP A CB    1 
ATOM 1376 C CG    . TRP A 1 193 ? 120.700 128.463 85.760  1.00 34.61  ? 249 TRP A CG    1 
ATOM 1377 C CD1   . TRP A 1 193 ? 119.549 127.733 85.819  1.00 34.61  ? 249 TRP A CD1   1 
ATOM 1378 C CD2   . TRP A 1 193 ? 120.724 129.272 86.941  1.00 34.61  ? 249 TRP A CD2   1 
ATOM 1379 N NE1   . TRP A 1 193 ? 118.871 128.014 86.982  1.00 34.61  ? 249 TRP A NE1   1 
ATOM 1380 C CE2   . TRP A 1 193 ? 119.569 128.961 87.684  1.00 34.61  ? 249 TRP A CE2   1 
ATOM 1381 C CE3   . TRP A 1 193 ? 121.615 130.223 87.445  1.00 34.61  ? 249 TRP A CE3   1 
ATOM 1382 C CZ2   . TRP A 1 193 ? 119.287 129.559 88.904  1.00 34.61  ? 249 TRP A CZ2   1 
ATOM 1383 C CZ3   . TRP A 1 193 ? 121.333 130.815 88.650  1.00 34.61  ? 249 TRP A CZ3   1 
ATOM 1384 C CH2   . TRP A 1 193 ? 120.176 130.483 89.369  1.00 34.61  ? 249 TRP A CH2   1 
ATOM 1385 N N     . GLN A 1 194 ? 123.555 126.750 87.048  1.00 32.30  ? 250 GLN A N     1 
ATOM 1386 C CA    . GLN A 1 194 ? 124.337 126.820 88.276  1.00 32.30  ? 250 GLN A CA    1 
ATOM 1387 C C     . GLN A 1 194 ? 125.669 126.101 88.173  1.00 32.30  ? 250 GLN A C     1 
ATOM 1388 O O     . GLN A 1 194 ? 126.329 125.897 89.197  1.00 32.30  ? 250 GLN A O     1 
ATOM 1389 C CB    . GLN A 1 194 ? 123.552 126.242 89.456  1.00 32.30  ? 250 GLN A CB    1 
ATOM 1390 C CG    . GLN A 1 194 ? 122.664 127.228 90.154  1.00 32.30  ? 250 GLN A CG    1 
ATOM 1391 C CD    . GLN A 1 194 ? 122.163 126.719 91.480  1.00 32.30  ? 250 GLN A CD    1 
ATOM 1392 O OE1   . GLN A 1 194 ? 122.497 125.612 91.900  1.00 32.30  ? 250 GLN A OE1   1 
ATOM 1393 N NE2   . GLN A 1 194 ? 121.351 127.525 92.154  1.00 32.30  ? 250 GLN A NE2   1 
ATOM 1394 N N     . ARG A 1 195 ? 126.087 125.718 86.979  1.00 28.76  ? 251 ARG A N     1 
ATOM 1395 C CA    . ARG A 1 195 ? 127.310 124.935 86.898  1.00 28.76  ? 251 ARG A CA    1 
ATOM 1396 C C     . ARG A 1 195 ? 128.404 125.539 86.020  1.00 28.76  ? 251 ARG A C     1 
ATOM 1397 O O     . ARG A 1 195 ? 129.032 124.795 85.258  1.00 28.76  ? 251 ARG A O     1 
ATOM 1398 C CB    . ARG A 1 195 ? 126.979 123.548 86.350  1.00 28.76  ? 251 ARG A CB    1 
ATOM 1399 C CG    . ARG A 1 195 ? 125.835 122.841 87.034  1.00 28.76  ? 251 ARG A CG    1 
ATOM 1400 C CD    . ARG A 1 195 ? 125.537 121.536 86.338  1.00 28.76  ? 251 ARG A CD    1 
ATOM 1401 N NE    . ARG A 1 195 ? 124.457 120.792 86.968  1.00 28.76  ? 251 ARG A NE    1 
ATOM 1402 C CZ    . ARG A 1 195 ? 124.041 119.604 86.556  1.00 28.76  ? 251 ARG A CZ    1 
ATOM 1403 N NH1   . ARG A 1 195 ? 124.593 119.002 85.518  1.00 28.76  ? 251 ARG A NH1   1 
ATOM 1404 N NH2   . ARG A 1 195 ? 123.051 119.002 87.205  1.00 28.76  ? 251 ARG A NH2   1 
ATOM 1405 N N     . PRO A 1 196 ? 128.683 126.859 86.065  1.00 33.54  ? 252 PRO A N     1 
ATOM 1406 C CA    . PRO A 1 196 ? 129.935 127.325 85.458  1.00 33.54  ? 252 PRO A CA    1 
ATOM 1407 C C     . PRO A 1 196 ? 131.039 127.580 86.473  1.00 33.54  ? 252 PRO A C     1 
ATOM 1408 O O     . PRO A 1 196 ? 132.204 127.735 86.097  1.00 33.54  ? 252 PRO A O     1 
ATOM 1409 C CB    . PRO A 1 196 ? 129.513 128.620 84.756  1.00 33.54  ? 252 PRO A CB    1 
ATOM 1410 C CG    . PRO A 1 196 ? 128.354 129.133 85.572  1.00 33.54  ? 252 PRO A CG    1 
ATOM 1411 C CD    . PRO A 1 196 ? 127.837 128.007 86.444  1.00 33.54  ? 252 PRO A CD    1 
ATOM 1412 N N     . HIS A 1 197 ? 130.687 127.636 87.764  1.00 34.36  ? 253 HIS A N     1 
ATOM 1413 C CA    . HIS A 1 197 ? 131.665 127.947 88.798  1.00 34.36  ? 253 HIS A CA    1 
ATOM 1414 C C     . HIS A 1 197 ? 131.401 127.196 90.101  1.00 34.36  ? 253 HIS A C     1 
ATOM 1415 O O     . HIS A 1 197 ? 131.692 127.720 91.181  1.00 34.36  ? 253 HIS A O     1 
ATOM 1416 C CB    . HIS A 1 197 ? 131.711 129.450 89.070  1.00 34.36  ? 253 HIS A CB    1 
ATOM 1417 C CG    . HIS A 1 197 ? 132.393 130.237 87.994  1.00 34.36  ? 253 HIS A CG    1 
ATOM 1418 N ND1   . HIS A 1 197 ? 131.728 130.707 86.882  1.00 34.36  ? 253 HIS A ND1   1 
ATOM 1419 C CD2   . HIS A 1 197 ? 133.680 130.634 87.859  1.00 34.36  ? 253 HIS A CD2   1 
ATOM 1420 C CE1   . HIS A 1 197 ? 132.576 131.362 86.108  1.00 34.36  ? 253 HIS A CE1   1 
ATOM 1421 N NE2   . HIS A 1 197 ? 133.768 131.332 86.679  1.00 34.36  ? 253 HIS A NE2   1 
ATOM 1422 N N     . LEU A 1 198 ? 130.837 125.992 90.035  1.00 33.43  ? 254 LEU A N     1 
ATOM 1423 C CA    . LEU A 1 198 ? 130.696 125.195 91.246  1.00 33.43  ? 254 LEU A CA    1 
ATOM 1424 C C     . LEU A 1 198 ? 132.069 124.944 91.858  1.00 33.43  ? 254 LEU A C     1 
ATOM 1425 O O     . LEU A 1 198 ? 133.053 124.706 91.151  1.00 33.43  ? 254 LEU A O     1 
ATOM 1426 C CB    . LEU A 1 198 ? 129.999 123.867 90.949  1.00 33.43  ? 254 LEU A CB    1 
ATOM 1427 C CG    . LEU A 1 198 ? 128.508 123.875 90.604  1.00 33.43  ? 254 LEU A CG    1 
ATOM 1428 C CD1   . LEU A 1 198 ? 128.052 122.505 90.154  1.00 33.43  ? 254 LEU A CD1   1 
ATOM 1429 C CD2   . LEU A 1 198 ? 127.685 124.336 91.781  1.00 33.43  ? 254 LEU A CD2   1 
ATOM 1430 N N     . SER A 1 199 ? 132.134 125.011 93.187  1.00 35.36  ? 255 SER A N     1 
ATOM 1431 C CA    . SER A 1 199 ? 133.413 125.043 93.888  1.00 35.36  ? 255 SER A CA    1 
ATOM 1432 C C     . SER A 1 199 ? 134.261 123.804 93.633  1.00 35.36  ? 255 SER A C     1 
ATOM 1433 O O     . SER A 1 199 ? 133.888 122.694 94.024  1.00 35.36  ? 255 SER A O     1 
ATOM 1434 C CB    . SER A 1 199 ? 133.192 125.209 95.390  1.00 35.36  ? 255 SER A CB    1 
ATOM 1435 O OG    . SER A 1 199 ? 132.803 126.532 95.703  1.00 35.36  ? 255 SER A OG    1 
ATOM 1436 N N     . THR A 1 200 ? 135.409 123.993 92.981  1.00 36.36  ? 256 THR A N     1 
ATOM 1437 C CA    . THR A 1 200 ? 136.346 122.902 92.750  1.00 36.36  ? 256 THR A CA    1 
ATOM 1438 C C     . THR A 1 200 ? 137.212 122.604 93.966  1.00 36.36  ? 256 THR A C     1 
ATOM 1439 O O     . THR A 1 200 ? 137.868 121.558 93.999  1.00 36.36  ? 256 THR A O     1 
ATOM 1440 C CB    . THR A 1 200 ? 137.245 123.224 91.556  1.00 36.36  ? 256 THR A CB    1 
ATOM 1441 O OG1   . THR A 1 200 ? 138.186 122.161 91.365  1.00 36.36  ? 256 THR A OG1   1 
ATOM 1442 C CG2   . THR A 1 200 ? 137.996 124.522 91.794  1.00 36.36  ? 256 THR A CG2   1 
ATOM 1443 N N     . LYS A 1 201 ? 137.234 123.492 94.954  1.00 36.83  ? 257 LYS A N     1 
ATOM 1444 C CA    . LYS A 1 201 ? 138.049 123.305 96.143  1.00 36.83  ? 257 LYS A CA    1 
ATOM 1445 C C     . LYS A 1 201 ? 137.274 122.547 97.219  1.00 36.83  ? 257 LYS A C     1 
ATOM 1446 O O     . LYS A 1 201 ? 136.079 122.269 97.089  1.00 36.83  ? 257 LYS A O     1 
ATOM 1447 C CB    . LYS A 1 201 ? 138.529 124.654 96.680  1.00 36.83  ? 257 LYS A CB    1 
ATOM 1448 C CG    . LYS A 1 201 ? 139.629 125.297 95.852  1.00 36.83  ? 257 LYS A CG    1 
ATOM 1449 C CD    . LYS A 1 201 ? 140.874 124.424 95.806  1.00 36.83  ? 257 LYS A CD    1 
ATOM 1450 C CE    . LYS A 1 201 ? 141.453 124.210 97.196  1.00 36.83  ? 257 LYS A CE    1 
ATOM 1451 N NZ    . LYS A 1 201 ? 142.647 123.320 97.170  1.00 36.83  ? 257 LYS A NZ    1 
ATOM 1452 N N     . ASN A 1 202 ? 137.979 122.212 98.297  1.00 38.99  ? 258 ASN A N     1 
ATOM 1453 C CA    . ASN A 1 202 ? 137.399 121.482 99.415  1.00 38.99  ? 258 ASN A CA    1 
ATOM 1454 C C     . ASN A 1 202 ? 136.687 122.446 100.351 1.00 38.99  ? 258 ASN A C     1 
ATOM 1455 O O     . ASN A 1 202 ? 137.239 123.489 100.718 1.00 38.99  ? 258 ASN A O     1 
ATOM 1456 C CB    . ASN A 1 202 ? 138.474 120.716 100.179 1.00 38.99  ? 258 ASN A CB    1 
ATOM 1457 C CG    . ASN A 1 202 ? 137.977 120.200 101.510 1.00 38.99  ? 258 ASN A CG    1 
ATOM 1458 O OD1   . ASN A 1 202 ? 138.229 120.800 102.554 1.00 38.99  ? 258 ASN A OD1   1 
ATOM 1459 N ND2   . ASN A 1 202 ? 137.263 119.080 101.482 1.00 38.99  ? 258 ASN A ND2   1 
ATOM 1460 N N     . LYS A 1 203 ? 135.443 122.110 100.697 1.00 32.84  ? 259 LYS A N     1 
ATOM 1461 C CA    . LYS A 1 203 ? 134.639 122.943 101.589 1.00 32.84  ? 259 LYS A CA    1 
ATOM 1462 C C     . LYS A 1 203 ? 133.522 122.055 102.119 1.00 32.84  ? 259 LYS A C     1 
ATOM 1463 O O     . LYS A 1 203 ? 133.547 120.842 101.912 1.00 32.84  ? 259 LYS A O     1 
ATOM 1464 C CB    . LYS A 1 203 ? 134.025 124.120 100.825 1.00 32.84  ? 259 LYS A CB    1 
ATOM 1465 C CG    . LYS A 1 203 ? 134.592 125.488 101.180 1.00 32.84  ? 259 LYS A CG    1 
ATOM 1466 C CD    . LYS A 1 203 ? 134.280 125.872 102.617 1.00 32.84  ? 259 LYS A CD    1 
ATOM 1467 C CE    . LYS A 1 203 ? 134.762 127.280 102.926 1.00 32.84  ? 259 LYS A CE    1 
ATOM 1468 N NZ    . LYS A 1 203 ? 134.484 127.666 104.337 1.00 32.84  ? 259 LYS A NZ    1 
ATOM 1469 N N     . ARG A 1 204 ? 132.535 122.645 102.782 1.00 30.17  ? 260 ARG A N     1 
ATOM 1470 C CA    . ARG A 1 204 ? 131.406 121.889 103.303 1.00 30.17  ? 260 ARG A CA    1 
ATOM 1471 C C     . ARG A 1 204 ? 130.412 121.550 102.207 1.00 30.17  ? 260 ARG A C     1 
ATOM 1472 O O     . ARG A 1 204 ? 130.183 122.330 101.281 1.00 30.17  ? 260 ARG A O     1 
ATOM 1473 C CB    . ARG A 1 204 ? 130.676 122.674 104.386 1.00 30.17  ? 260 ARG A CB    1 
ATOM 1474 C CG    . ARG A 1 204 ? 131.367 122.735 105.719 1.00 30.17  ? 260 ARG A CG    1 
ATOM 1475 C CD    . ARG A 1 204 ? 130.457 123.431 106.701 1.00 30.17  ? 260 ARG A CD    1 
ATOM 1476 N NE    . ARG A 1 204 ? 129.188 122.726 106.818 1.00 30.17  ? 260 ARG A NE    1 
ATOM 1477 C CZ    . ARG A 1 204 ? 128.149 123.172 107.505 1.00 30.17  ? 260 ARG A CZ    1 
ATOM 1478 N NH1   . ARG A 1 204 ? 128.177 124.340 108.116 1.00 30.17  ? 260 ARG A NH1   1 
ATOM 1479 N NH2   . ARG A 1 204 ? 127.052 122.426 107.579 1.00 30.17  ? 260 ARG A NH2   1 
ATOM 1480 N N     . ILE A 1 205 ? 129.798 120.383 102.329 1.00 28.66  ? 261 ILE A N     1 
ATOM 1481 C CA    . ILE A 1 205 ? 128.640 120.037 101.518 1.00 28.66  ? 261 ILE A CA    1 
ATOM 1482 C C     . ILE A 1 205 ? 127.419 120.134 102.426 1.00 28.66  ? 261 ILE A C     1 
ATOM 1483 O O     . ILE A 1 205 ? 127.180 119.273 103.281 1.00 28.66  ? 261 ILE A O     1 
ATOM 1484 C CB    . ILE A 1 205 ? 128.764 118.659 100.849 1.00 28.66  ? 261 ILE A CB    1 
ATOM 1485 C CG1   . ILE A 1 205 ? 127.525 118.359 100.009 1.00 28.66  ? 261 ILE A CG1   1 
ATOM 1486 C CG2   . ILE A 1 205 ? 129.046 117.544 101.844 1.00 28.66  ? 261 ILE A CG2   1 
ATOM 1487 C CD1   . ILE A 1 205 ? 127.358 119.283 98.823  1.00 28.66  ? 261 ILE A CD1   1 
ATOM 1488 N N     . ARG A 1 206 ? 126.651 121.204 102.260 1.00 30.64  ? 262 ARG A N     1 
ATOM 1489 C CA    . ARG A 1 206 ? 125.345 121.302 102.886 1.00 30.64  ? 262 ARG A CA    1 
ATOM 1490 C C     . ARG A 1 206 ? 124.413 120.396 102.098 1.00 30.64  ? 262 ARG A C     1 
ATOM 1491 O O     . ARG A 1 206 ? 124.846 119.667 101.204 1.00 30.64  ? 262 ARG A O     1 
ATOM 1492 C CB    . ARG A 1 206 ? 124.880 122.752 102.918 1.00 30.64  ? 262 ARG A CB    1 
ATOM 1493 C CG    . ARG A 1 206 ? 125.369 123.531 104.120 1.00 30.64  ? 262 ARG A CG    1 
ATOM 1494 C CD    . ARG A 1 206 ? 125.310 125.027 103.872 1.00 30.64  ? 262 ARG A CD    1 
ATOM 1495 N NE    . ARG A 1 206 ? 125.787 125.376 102.540 1.00 30.64  ? 262 ARG A NE    1 
ATOM 1496 C CZ    . ARG A 1 206 ? 125.208 126.261 101.743 1.00 30.64  ? 262 ARG A CZ    1 
ATOM 1497 N NH1   . ARG A 1 206 ? 124.112 126.905 102.106 1.00 30.64  ? 262 ARG A NH1   1 
ATOM 1498 N NH2   . ARG A 1 206 ? 125.744 126.510 100.552 1.00 30.64  ? 262 ARG A NH2   1 
ATOM 1499 N N     . LYS A 1 207 ? 123.133 120.425 102.446 1.00 30.21  ? 263 LYS A N     1 
ATOM 1500 C CA    . LYS A 1 207 ? 122.157 119.584 101.767 1.00 30.21  ? 263 LYS A CA    1 
ATOM 1501 C C     . LYS A 1 207 ? 120.927 120.397 101.414 1.00 30.21  ? 263 LYS A C     1 
ATOM 1502 O O     . LYS A 1 207 ? 120.883 121.601 101.667 1.00 30.21  ? 263 LYS A O     1 
ATOM 1503 C CB    . LYS A 1 207 ? 121.760 118.412 102.662 1.00 30.21  ? 263 LYS A CB    1 
ATOM 1504 C CG    . LYS A 1 207 ? 122.607 117.164 102.482 1.00 30.21  ? 263 LYS A CG    1 
ATOM 1505 C CD    . LYS A 1 207 ? 122.273 116.477 101.169 1.00 30.21  ? 263 LYS A CD    1 
ATOM 1506 C CE    . LYS A 1 207 ? 120.812 116.056 101.129 1.00 30.21  ? 263 LYS A CE    1 
ATOM 1507 N NZ    . LYS A 1 207 ? 120.428 115.487 99.808  1.00 30.21  ? 263 LYS A NZ    1 
ATOM 1508 N N     . TRP A 1 208 ? 119.930 119.747 100.827 1.00 31.00  ? 264 TRP A N     1 
ATOM 1509 C CA    . TRP A 1 208 ? 118.695 120.438 100.491 1.00 31.00  ? 264 TRP A CA    1 
ATOM 1510 C C     . TRP A 1 208 ? 118.033 120.958 101.760 1.00 31.00  ? 264 TRP A C     1 
ATOM 1511 O O     . TRP A 1 208 ? 117.473 122.054 101.768 1.00 31.00  ? 264 TRP A O     1 
ATOM 1512 C CB    . TRP A 1 208 ? 117.762 119.525 99.680  1.00 31.00  ? 264 TRP A CB    1 
ATOM 1513 C CG    . TRP A 1 208 ? 116.810 118.702 100.487 1.00 31.00  ? 264 TRP A CG    1 
ATOM 1514 C CD1   . TRP A 1 208 ? 117.044 117.474 101.032 1.00 31.00  ? 264 TRP A CD1   1 
ATOM 1515 C CD2   . TRP A 1 208 ? 115.464 119.047 100.835 1.00 31.00  ? 264 TRP A CD2   1 
ATOM 1516 N NE1   . TRP A 1 208 ? 115.929 117.036 101.703 1.00 31.00  ? 264 TRP A NE1   1 
ATOM 1517 C CE2   . TRP A 1 208 ? 114.945 117.985 101.599 1.00 31.00  ? 264 TRP A CE2   1 
ATOM 1518 C CE3   . TRP A 1 208 ? 114.651 120.156 100.582 1.00 31.00  ? 264 TRP A CE3   1 
ATOM 1519 C CZ2   . TRP A 1 208 ? 113.648 117.995 102.107 1.00 31.00  ? 264 TRP A CZ2   1 
ATOM 1520 C CZ3   . TRP A 1 208 ? 113.366 120.165 101.087 1.00 31.00  ? 264 TRP A CZ3   1 
ATOM 1521 C CH2   . TRP A 1 208 ? 112.877 119.092 101.840 1.00 31.00  ? 264 TRP A CH2   1 
ATOM 1522 N N     . TYR A 1 209 ? 118.094 120.178 102.833 1.00 32.44  ? 265 TYR A N     1 
ATOM 1523 C CA    . TYR A 1 209 ? 117.442 120.566 104.077 1.00 32.44  ? 265 TYR A CA    1 
ATOM 1524 C C     . TYR A 1 209 ? 118.269 121.497 104.959 1.00 32.44  ? 265 TYR A C     1 
ATOM 1525 O O     . TYR A 1 209 ? 117.889 121.750 106.102 1.00 32.44  ? 265 TYR A O     1 
ATOM 1526 C CB    . TYR A 1 209 ? 117.087 119.323 104.888 1.00 32.44  ? 265 TYR A CB    1 
ATOM 1527 C CG    . TYR A 1 209 ? 118.275 118.474 105.300 1.00 32.44  ? 265 TYR A CG    1 
ATOM 1528 C CD1   . TYR A 1 209 ? 118.996 118.757 106.455 1.00 32.44  ? 265 TYR A CD1   1 
ATOM 1529 C CD2   . TYR A 1 209 ? 118.663 117.378 104.545 1.00 32.44  ? 265 TYR A CD2   1 
ATOM 1530 C CE1   . TYR A 1 209 ? 120.075 117.987 106.832 1.00 32.44  ? 265 TYR A CE1   1 
ATOM 1531 C CE2   . TYR A 1 209 ? 119.734 116.597 104.925 1.00 32.44  ? 265 TYR A CE2   1 
ATOM 1532 C CZ    . TYR A 1 209 ? 120.439 116.908 106.066 1.00 32.44  ? 265 TYR A CZ    1 
ATOM 1533 O OH    . TYR A 1 209 ? 121.510 116.136 106.445 1.00 32.44  ? 265 TYR A OH    1 
ATOM 1534 N N     . ALA A 1 210 ? 119.395 121.999 104.469 1.00 31.63  ? 266 ALA A N     1 
ATOM 1535 C CA    . ALA A 1 210 ? 120.138 122.926 105.309 1.00 31.63  ? 266 ALA A CA    1 
ATOM 1536 C C     . ALA A 1 210 ? 119.381 124.241 105.461 1.00 31.63  ? 266 ALA A C     1 
ATOM 1537 O O     . ALA A 1 210 ? 118.819 124.767 104.496 1.00 31.63  ? 266 ALA A O     1 
ATOM 1538 C CB    . ALA A 1 210 ? 121.522 123.180 104.724 1.00 31.63  ? 266 ALA A CB    1 
ATOM 1539 N N     . ARG A 1 211 ? 119.369 124.776 106.686 1.00 35.01  ? 267 ARG A N     1 
ATOM 1540 C CA    . ARG A 1 211 ? 118.639 126.008 106.971 1.00 35.01  ? 267 ARG A CA    1 
ATOM 1541 C C     . ARG A 1 211 ? 119.384 127.267 106.552 1.00 35.01  ? 267 ARG A C     1 
ATOM 1542 O O     . ARG A 1 211 ? 118.768 128.337 106.501 1.00 35.01  ? 267 ARG A O     1 
ATOM 1543 C CB    . ARG A 1 211 ? 118.295 126.099 108.456 1.00 35.01  ? 267 ARG A CB    1 
ATOM 1544 C CG    . ARG A 1 211 ? 117.397 124.983 108.953 1.00 35.01  ? 267 ARG A CG    1 
ATOM 1545 C CD    . ARG A 1 211 ? 116.895 125.281 110.351 1.00 35.01  ? 267 ARG A CD    1 
ATOM 1546 N NE    . ARG A 1 211 ? 116.318 126.617 110.436 1.00 35.01  ? 267 ARG A NE    1 
ATOM 1547 C CZ    . ARG A 1 211 ? 116.820 127.603 111.164 1.00 35.01  ? 267 ARG A CZ    1 
ATOM 1548 N NH1   . ARG A 1 211 ? 117.923 127.443 111.877 1.00 35.01  ? 267 ARG A NH1   1 
ATOM 1549 N NH2   . ARG A 1 211 ? 116.202 128.780 111.174 1.00 35.01  ? 267 ARG A NH2   1 
ATOM 1550 N N     . ALA A 1 212 ? 120.683 127.180 106.259 1.00 33.90  ? 268 ALA A N     1 
ATOM 1551 C CA    . ALA A 1 212 ? 121.358 128.317 105.648 1.00 33.90  ? 268 ALA A CA    1 
ATOM 1552 C C     . ALA A 1 212 ? 120.807 128.595 104.259 1.00 33.90  ? 268 ALA A C     1 
ATOM 1553 O O     . ALA A 1 212 ? 120.898 129.723 103.765 1.00 33.90  ? 268 ALA A O     1 
ATOM 1554 C CB    . ALA A 1 212 ? 122.863 128.072 105.587 1.00 33.90  ? 268 ALA A CB    1 
ATOM 1555 N N     . ASN A 1 213 ? 120.216 127.577 103.628 1.00 35.65  ? 269 ASN A N     1 
ATOM 1556 C CA    . ASN A 1 213 ? 119.662 127.714 102.272 1.00 35.65  ? 269 ASN A CA    1 
ATOM 1557 C C     . ASN A 1 213 ? 118.233 128.211 102.249 1.00 35.65  ? 269 ASN A C     1 
ATOM 1558 O O     . ASN A 1 213 ? 117.715 128.543 101.182 1.00 35.65  ? 269 ASN A O     1 
ATOM 1559 C CB    . ASN A 1 213 ? 119.652 126.347 101.584 1.00 35.65  ? 269 ASN A CB    1 
ATOM 1560 C CG    . ASN A 1 213 ? 121.010 125.931 101.092 1.00 35.65  ? 269 ASN A CG    1 
ATOM 1561 O OD1   . ASN A 1 213 ? 121.848 126.772 100.818 1.00 35.65  ? 269 ASN A OD1   1 
ATOM 1562 N ND2   . ASN A 1 213 ? 121.228 124.628 100.960 1.00 35.65  ? 269 ASN A ND2   1 
ATOM 1563 N N     . TRP A 1 214 ? 117.580 128.260 103.402 1.00 39.30  ? 270 TRP A N     1 
ATOM 1564 C CA    . TRP A 1 214 ? 116.172 128.618 103.450 1.00 39.30  ? 270 TRP A CA    1 
ATOM 1565 C C     . TRP A 1 214 ? 115.860 129.782 104.377 1.00 39.30  ? 270 TRP A C     1 
ATOM 1566 O O     . TRP A 1 214 ? 114.679 130.071 104.601 1.00 39.30  ? 270 TRP A O     1 
ATOM 1567 C CB    . TRP A 1 214 ? 115.331 127.402 103.863 1.00 39.30  ? 270 TRP A CB    1 
ATOM 1568 C CG    . TRP A 1 214 ? 115.326 126.313 102.841 1.00 39.30  ? 270 TRP A CG    1 
ATOM 1569 C CD1   . TRP A 1 214 ? 116.386 125.554 102.449 1.00 39.30  ? 270 TRP A CD1   1 
ATOM 1570 C CD2   . TRP A 1 214 ? 114.205 125.865 102.076 1.00 39.30  ? 270 TRP A CD2   1 
ATOM 1571 N NE1   . TRP A 1 214 ? 115.995 124.659 101.484 1.00 39.30  ? 270 TRP A NE1   1 
ATOM 1572 C CE2   . TRP A 1 214 ? 114.659 124.831 101.237 1.00 39.30  ? 270 TRP A CE2   1 
ATOM 1573 C CE3   . TRP A 1 214 ? 112.861 126.237 102.018 1.00 39.30  ? 270 TRP A CE3   1 
ATOM 1574 C CZ2   . TRP A 1 214 ? 113.818 124.166 100.352 1.00 39.30  ? 270 TRP A CZ2   1 
ATOM 1575 C CZ3   . TRP A 1 214 ? 112.027 125.575 101.137 1.00 39.30  ? 270 TRP A CZ3   1 
ATOM 1576 C CH2   . TRP A 1 214 ? 112.510 124.551 100.316 1.00 39.30  ? 270 TRP A CH2   1 
ATOM 1577 N N     . ARG A 1 215 ? 116.866 130.452 104.926 1.00 39.34  ? 271 ARG A N     1 
ATOM 1578 C CA    . ARG A 1 215 ? 116.606 131.586 105.799 1.00 39.34  ? 271 ARG A CA    1 
ATOM 1579 C C     . ARG A 1 215 ? 115.954 132.721 105.019 1.00 39.34  ? 271 ARG A C     1 
ATOM 1580 O O     . ARG A 1 215 ? 116.217 132.914 103.828 1.00 39.34  ? 271 ARG A O     1 
ATOM 1581 C CB    . ARG A 1 215 ? 117.905 132.056 106.454 1.00 39.34  ? 271 ARG A CB    1 
ATOM 1582 C CG    . ARG A 1 215 ? 118.871 132.749 105.515 1.00 39.34  ? 271 ARG A CG    1 
ATOM 1583 C CD    . ARG A 1 215 ? 120.210 132.960 106.181 1.00 39.34  ? 271 ARG A CD    1 
ATOM 1584 N NE    . ARG A 1 215 ? 121.089 133.801 105.382 1.00 39.34  ? 271 ARG A NE    1 
ATOM 1585 C CZ    . ARG A 1 215 ? 121.813 133.366 104.361 1.00 39.34  ? 271 ARG A CZ    1 
ATOM 1586 N NH1   . ARG A 1 215 ? 121.802 132.094 103.998 1.00 39.34  ? 271 ARG A NH1   1 
ATOM 1587 N NH2   . ARG A 1 215 ? 122.560 134.230 103.681 1.00 39.34  ? 271 ARG A NH2   1 
ATOM 1588 N N     . ARG A 1 216 ? 115.107 133.469 105.728 1.00 41.93  ? 272 ARG A N     1 
ATOM 1589 C CA    . ARG A 1 216 ? 114.378 134.570 105.109 1.00 41.93  ? 272 ARG A CA    1 
ATOM 1590 C C     . ARG A 1 216 ? 115.189 135.829 104.918 1.00 41.93  ? 272 ARG A C     1 
ATOM 1591 O O     . ARG A 1 216 ? 115.428 136.577 105.869 1.00 41.93  ? 272 ARG A O     1 
ATOM 1592 C CB    . ARG A 1 216 ? 113.115 134.880 105.929 1.00 41.93  ? 272 ARG A CB    1 
ATOM 1593 C CG    . ARG A 1 216 ? 112.328 136.108 105.485 1.00 41.93  ? 272 ARG A CG    1 
ATOM 1594 C CD    . ARG A 1 216 ? 111.671 135.910 104.131 1.00 41.93  ? 272 ARG A CD    1 
ATOM 1595 N NE    . ARG A 1 216 ? 112.129 136.882 103.144 1.00 41.93  ? 272 ARG A NE    1 
ATOM 1596 C CZ    . ARG A 1 216 ? 111.703 136.919 101.886 1.00 41.93  ? 272 ARG A CZ    1 
ATOM 1597 N NH1   . ARG A 1 216 ? 110.809 136.037 101.462 1.00 41.93  ? 272 ARG A NH1   1 
ATOM 1598 N NH2   . ARG A 1 216 ? 112.169 137.836 101.051 1.00 41.93  ? 272 ARG A NH2   1 
ATOM 1599 N N     . LYS A 1 217 ? 115.649 136.053 103.701 1.00 42.20  ? 273 LYS A N     1 
ATOM 1600 C CA    . LYS A 1 217 ? 116.339 137.291 103.375 1.00 42.20  ? 273 LYS A CA    1 
ATOM 1601 C C     . LYS A 1 217 ? 115.751 137.826 102.078 1.00 42.20  ? 273 LYS A C     1 
ATOM 1602 O O     . LYS A 1 217 ? 115.204 137.059 101.278 1.00 42.20  ? 273 LYS A O     1 
ATOM 1603 C CB    . LYS A 1 217 ? 117.859 137.091 103.262 1.00 42.20  ? 273 LYS A CB    1 
ATOM 1604 C CG    . LYS A 1 217 ? 118.364 136.529 101.950 1.00 42.20  ? 273 LYS A CG    1 
ATOM 1605 C CD    . LYS A 1 217 ? 119.881 136.395 101.989 1.00 42.20  ? 273 LYS A CD    1 
ATOM 1606 C CE    . LYS A 1 217 ? 120.452 136.043 100.626 1.00 42.20  ? 273 LYS A CE    1 
ATOM 1607 N NZ    . LYS A 1 217 ? 120.432 137.204 99.697  1.00 42.20  ? 273 LYS A NZ    1 
ATOM 1608 N N     . PRO A 1 218 ? 115.834 139.142 101.848 1.00 42.34  ? 274 PRO A N     1 
ATOM 1609 C CA    . PRO A 1 218 ? 115.023 139.753 100.778 1.00 42.34  ? 274 PRO A CA    1 
ATOM 1610 C C     . PRO A 1 218 ? 115.271 139.192 99.386  1.00 42.34  ? 274 PRO A C     1 
ATOM 1611 O O     . PRO A 1 218 ? 114.371 139.265 98.539  1.00 42.34  ? 274 PRO A O     1 
ATOM 1612 C CB    . PRO A 1 218 ? 115.411 141.236 100.857 1.00 42.34  ? 274 PRO A CB    1 
ATOM 1613 C CG    . PRO A 1 218 ? 115.830 141.435 102.267 1.00 42.34  ? 274 PRO A CG    1 
ATOM 1614 C CD    . PRO A 1 218 ? 116.518 140.162 102.664 1.00 42.34  ? 274 PRO A CD    1 
ATOM 1615 N N     . GLY A 1 219 ? 116.449 138.640 99.114  1.00 41.02  ? 275 GLY A N     1 
ATOM 1616 C CA    . GLY A 1 219 ? 116.733 138.122 97.789  1.00 41.02  ? 275 GLY A CA    1 
ATOM 1617 C C     . GLY A 1 219 ? 116.272 136.694 97.587  1.00 41.02  ? 275 GLY A C     1 
ATOM 1618 O O     . GLY A 1 219 ? 116.653 136.048 96.607  1.00 41.02  ? 275 GLY A O     1 
ATOM 1619 N N     . ARG A 1 220 ? 115.441 136.191 98.498  1.00 41.18  ? 276 ARG A N     1 
ATOM 1620 C CA    . ARG A 1 220 ? 115.039 134.792 98.500  1.00 41.18  ? 276 ARG A CA    1 
ATOM 1621 C C     . ARG A 1 220 ? 113.520 134.709 98.550  1.00 41.18  ? 276 ARG A C     1 
ATOM 1622 O O     . ARG A 1 220 ? 112.860 135.493 99.235  1.00 41.18  ? 276 ARG A O     1 
ATOM 1623 C CB    . ARG A 1 220 ? 115.679 134.054 99.683  1.00 41.18  ? 276 ARG A CB    1 
ATOM 1624 C CG    . ARG A 1 220 ? 115.519 132.550 99.684  1.00 41.18  ? 276 ARG A CG    1 
ATOM 1625 C CD    . ARG A 1 220 ? 116.524 131.937 100.644 1.00 41.18  ? 276 ARG A CD    1 
ATOM 1626 N NE    . ARG A 1 220 ? 117.883 132.357 100.319 1.00 41.18  ? 276 ARG A NE    1 
ATOM 1627 C CZ    . ARG A 1 220 ? 118.966 131.987 100.988 1.00 41.18  ? 276 ARG A CZ    1 
ATOM 1628 N NH1   . ARG A 1 220 ? 118.888 131.207 102.052 1.00 41.18  ? 276 ARG A NH1   1 
ATOM 1629 N NH2   . ARG A 1 220 ? 120.159 132.409 100.577 1.00 41.18  ? 276 ARG A NH2   1 
ATOM 1630 N N     . LYS A 1 221 ? 112.964 133.740 97.816  1.00 42.30  ? 277 LYS A N     1 
ATOM 1631 C CA    . LYS A 1 221 ? 111.521 133.712 97.597  1.00 42.30  ? 277 LYS A CA    1 
ATOM 1632 C C     . LYS A 1 221 ? 110.881 132.351 97.863  1.00 42.30  ? 277 LYS A C     1 
ATOM 1633 O O     . LYS A 1 221 ? 109.673 132.199 97.637  1.00 42.30  ? 277 LYS A O     1 
ATOM 1634 C CB    . LYS A 1 221 ? 111.201 134.158 96.165  1.00 42.30  ? 277 LYS A CB    1 
ATOM 1635 C CG    . LYS A 1 221 ? 109.859 134.851 96.010  1.00 42.30  ? 277 LYS A CG    1 
ATOM 1636 C CD    . LYS A 1 221 ? 109.682 135.415 94.608  1.00 42.30  ? 277 LYS A CD    1 
ATOM 1637 C CE    . LYS A 1 221 ? 110.169 134.440 93.548  1.00 42.30  ? 277 LYS A CE    1 
ATOM 1638 N NZ    . LYS A 1 221 ? 110.071 135.014 92.178  1.00 42.30  ? 277 LYS A NZ    1 
ATOM 1639 N N     . SER A 1 222 ? 111.637 131.362 98.337  1.00 40.93  ? 278 SER A N     1 
ATOM 1640 C CA    . SER A 1 222 ? 111.098 130.053 98.687  1.00 40.93  ? 278 SER A CA    1 
ATOM 1641 C C     . SER A 1 222 ? 111.381 129.710 100.142 1.00 40.93  ? 278 SER A C     1 
ATOM 1642 O O     . SER A 1 222 ? 111.850 128.609 100.436 1.00 40.93  ? 278 SER A O     1 
ATOM 1643 C CB    . SER A 1 222 ? 111.674 128.975 97.771  1.00 40.93  ? 278 SER A CB    1 
ATOM 1644 O OG    . SER A 1 222 ? 113.071 129.146 97.613  1.00 40.93  ? 278 SER A OG    1 
ATOM 1645 N N     . VAL A 1 223 ? 111.107 130.638 101.059 1.00 44.13  ? 279 VAL A N     1 
ATOM 1646 C CA    . VAL A 1 223 ? 111.755 130.605 102.362 1.00 44.13  ? 279 VAL A CA    1 
ATOM 1647 C C     . VAL A 1 223 ? 111.050 129.659 103.326 1.00 44.13  ? 279 VAL A C     1 
ATOM 1648 O O     . VAL A 1 223 ? 109.822 129.686 103.483 1.00 44.13  ? 279 VAL A O     1 
ATOM 1649 C CB    . VAL A 1 223 ? 111.838 132.029 102.936 1.00 44.13  ? 279 VAL A CB    1 
ATOM 1650 C CG1   . VAL A 1 223 ? 112.781 132.876 102.101 1.00 44.13  ? 279 VAL A CG1   1 
ATOM 1651 C CG2   . VAL A 1 223 ? 110.460 132.673 102.971 1.00 44.13  ? 279 VAL A CG2   1 
ATOM 1652 N N     . LEU A 1 224 ? 111.843 128.791 103.947 1.00 46.42  ? 280 LEU A N     1 
ATOM 1653 C CA    . LEU A 1 224 ? 111.529 128.148 105.222 1.00 46.42  ? 280 LEU A CA    1 
ATOM 1654 C C     . LEU A 1 224 ? 110.195 127.404 105.215 1.00 46.42  ? 280 LEU A C     1 
ATOM 1655 O O     . LEU A 1 224 ? 109.225 127.798 105.863 1.00 46.42  ? 280 LEU A O     1 
ATOM 1656 C CB    . LEU A 1 224 ? 111.571 129.159 106.364 1.00 46.42  ? 280 LEU A CB    1 
ATOM 1657 C CG    . LEU A 1 224 ? 111.816 128.522 107.735 1.00 46.42  ? 280 LEU A CG    1 
ATOM 1658 C CD1   . LEU A 1 224 ? 112.955 127.515 107.669 1.00 46.42  ? 280 LEU A CD1   1 
ATOM 1659 C CD2   . LEU A 1 224 ? 112.099 129.588 108.781 1.00 46.42  ? 280 LEU A CD2   1 
ATOM 1660 N N     . ASP A 1 225 ? 110.153 126.314 104.454 1.00 48.20  ? 281 ASP A N     1 
ATOM 1661 C CA    . ASP A 1 225 ? 109.172 125.281 104.749 1.00 48.20  ? 281 ASP A CA    1 
ATOM 1662 C C     . ASP A 1 225 ? 109.397 124.801 106.179 1.00 48.20  ? 281 ASP A C     1 
ATOM 1663 O O     . ASP A 1 225 ? 110.485 124.330 106.522 1.00 48.20  ? 281 ASP A O     1 
ATOM 1664 C CB    . ASP A 1 225 ? 109.293 124.124 103.760 1.00 48.20  ? 281 ASP A CB    1 
ATOM 1665 C CG    . ASP A 1 225 ? 108.560 124.392 102.460 1.00 48.20  ? 281 ASP A CG    1 
ATOM 1666 O OD1   . ASP A 1 225 ? 107.576 125.162 102.479 1.00 48.20  ? 281 ASP A OD1   1 
ATOM 1667 O OD2   . ASP A 1 225 ? 108.965 123.831 101.420 1.00 48.20  ? 281 ASP A OD2   1 
ATOM 1668 N N     . GLU A 1 226 ? 108.363 124.934 107.014 1.00 48.79  ? 282 GLU A N     1 
ATOM 1669 C CA    . GLU A 1 226 ? 108.564 124.902 108.462 1.00 48.79  ? 282 GLU A CA    1 
ATOM 1670 C C     . GLU A 1 226 ? 109.098 123.558 108.946 1.00 48.79  ? 282 GLU A C     1 
ATOM 1671 O O     . GLU A 1 226 ? 110.014 123.512 109.776 1.00 48.79  ? 282 GLU A O     1 
ATOM 1672 C CB    . GLU A 1 226 ? 107.257 125.245 109.177 1.00 48.79  ? 282 GLU A CB    1 
ATOM 1673 C CG    . GLU A 1 226 ? 107.105 126.721 109.511 1.00 48.79  ? 282 GLU A CG    1 
ATOM 1674 C CD    . GLU A 1 226 ? 106.961 127.588 108.276 1.00 48.79  ? 282 GLU A CD    1 
ATOM 1675 O OE1   . GLU A 1 226 ? 106.338 127.130 107.296 1.00 48.79  ? 282 GLU A OE1   1 
ATOM 1676 O OE2   . GLU A 1 226 ? 107.472 128.728 108.286 1.00 48.79  ? 282 GLU A OE2   1 
ATOM 1677 N N     . ALA A 1 227 ? 108.541 122.456 108.451 1.00 44.56  ? 283 ALA A N     1 
ATOM 1678 C CA    . ALA A 1 227 ? 108.876 121.135 108.964 1.00 44.56  ? 283 ALA A CA    1 
ATOM 1679 C C     . ALA A 1 227 ? 109.754 120.317 108.029 1.00 44.56  ? 283 ALA A C     1 
ATOM 1680 O O     . ALA A 1 227 ? 110.304 119.301 108.461 1.00 44.56  ? 283 ALA A O     1 
ATOM 1681 C CB    . ALA A 1 227 ? 107.594 120.352 109.275 1.00 44.56  ? 283 ALA A CB    1 
ATOM 1682 N N     . LYS A 1 228 ? 109.900 120.724 106.767 1.00 41.70  ? 284 LYS A N     1 
ATOM 1683 C CA    . LYS A 1 228 ? 110.590 119.884 105.792 1.00 41.70  ? 284 LYS A CA    1 
ATOM 1684 C C     . LYS A 1 228 ? 112.074 119.765 106.115 1.00 41.70  ? 284 LYS A C     1 
ATOM 1685 O O     . LYS A 1 228 ? 112.637 118.660 106.121 1.00 41.70  ? 284 LYS A O     1 
ATOM 1686 C CB    . LYS A 1 228 ? 110.386 120.447 104.388 1.00 41.70  ? 284 LYS A CB    1 
ATOM 1687 C CG    . LYS A 1 228 ? 108.937 120.493 103.949 1.00 41.70  ? 284 LYS A CG    1 
ATOM 1688 C CD    . LYS A 1 228 ? 108.226 119.186 104.247 1.00 41.70  ? 284 LYS A CD    1 
ATOM 1689 C CE    . LYS A 1 228 ? 108.694 118.077 103.318 1.00 41.70  ? 284 LYS A CE    1 
ATOM 1690 N NZ    . LYS A 1 228 ? 108.373 116.727 103.860 1.00 41.70  ? 284 LYS A NZ    1 
ATOM 1691 N N     . LEU A 1 229 ? 112.721 120.896 106.389 1.00 38.42  ? 285 LEU A N     1 
ATOM 1692 C CA    . LEU A 1 229 ? 114.137 120.879 106.728 1.00 38.42  ? 285 LEU A CA    1 
ATOM 1693 C C     . LEU A 1 229 ? 114.381 120.104 108.017 1.00 38.42  ? 285 LEU A C     1 
ATOM 1694 O O     . LEU A 1 229 ? 115.339 119.328 108.114 1.00 38.42  ? 285 LEU A O     1 
ATOM 1695 C CB    . LEU A 1 229 ? 114.658 122.311 106.852 1.00 38.42  ? 285 LEU A CB    1 
ATOM 1696 C CG    . LEU A 1 229 ? 114.798 123.122 105.561 1.00 38.42  ? 285 LEU A CG    1 
ATOM 1697 C CD1   . LEU A 1 229 ? 113.453 123.613 105.054 1.00 38.42  ? 285 LEU A CD1   1 
ATOM 1698 C CD2   . LEU A 1 229 ? 115.741 124.292 105.765 1.00 38.42  ? 285 LEU A CD2   1 
ATOM 1699 N N     . LYS A 1 230 ? 113.518 120.296 109.017 1.00 38.70  ? 286 LYS A N     1 
ATOM 1700 C CA    . LYS A 1 230 ? 113.671 119.580 110.280 1.00 38.70  ? 286 LYS A CA    1 
ATOM 1701 C C     . LYS A 1 230 ? 113.523 118.078 110.079 1.00 38.70  ? 286 LYS A C     1 
ATOM 1702 O O     . LYS A 1 230 ? 114.303 117.286 110.623 1.00 38.70  ? 286 LYS A O     1 
ATOM 1703 C CB    . LYS A 1 230 ? 112.652 120.093 111.299 1.00 38.70  ? 286 LYS A CB    1 
ATOM 1704 C CG    . LYS A 1 230 ? 113.150 121.254 112.142 1.00 38.70  ? 286 LYS A CG    1 
ATOM 1705 C CD    . LYS A 1 230 ? 114.318 120.837 113.021 1.00 38.70  ? 286 LYS A CD    1 
ATOM 1706 C CE    . LYS A 1 230 ? 113.887 119.820 114.066 1.00 38.70  ? 286 LYS A CE    1 
ATOM 1707 N NZ    . LYS A 1 230 ? 115.039 119.331 114.873 1.00 38.70  ? 286 LYS A NZ    1 
ATOM 1708 N N     . GLU A 1 231 ? 112.530 117.667 109.291 1.00 36.09  ? 287 GLU A N     1 
ATOM 1709 C CA    . GLU A 1 231 ? 112.341 116.246 109.035 1.00 36.09  ? 287 GLU A CA    1 
ATOM 1710 C C     . GLU A 1 231 ? 113.541 115.651 108.314 1.00 36.09  ? 287 GLU A C     1 
ATOM 1711 O O     . GLU A 1 231 ? 114.014 114.570 108.678 1.00 36.09  ? 287 GLU A O     1 
ATOM 1712 C CB    . GLU A 1 231 ? 111.068 116.017 108.226 1.00 36.09  ? 287 GLU A CB    1 
ATOM 1713 C CG    . GLU A 1 231 ? 110.696 114.552 108.085 1.00 36.09  ? 287 GLU A CG    1 
ATOM 1714 C CD    . GLU A 1 231 ? 109.496 114.338 107.187 1.00 36.09  ? 287 GLU A CD    1 
ATOM 1715 O OE1   . GLU A 1 231 ? 109.212 115.221 106.351 1.00 36.09  ? 287 GLU A OE1   1 
ATOM 1716 O OE2   . GLU A 1 231 ? 108.835 113.286 107.317 1.00 36.09  ? 287 GLU A OE2   1 
ATOM 1717 N N     . ALA A 1 232 ? 114.053 116.339 107.296 1.00 33.41  ? 288 ALA A N     1 
ATOM 1718 C CA    . ALA A 1 232 ? 115.174 115.764 106.561 1.00 33.41  ? 288 ALA A CA    1 
ATOM 1719 C C     . ALA A 1 232 ? 116.499 115.896 107.301 1.00 33.41  ? 288 ALA A C     1 
ATOM 1720 O O     . ALA A 1 232 ? 117.479 115.265 106.895 1.00 33.41  ? 288 ALA A O     1 
ATOM 1721 C CB    . ALA A 1 232 ? 115.275 116.396 105.175 1.00 33.41  ? 288 ALA A CB    1 
ATOM 1722 N N     . ALA A 1 233 ? 116.565 116.711 108.354 1.00 34.26  ? 289 ALA A N     1 
ATOM 1723 C CA    . ALA A 1 233 ? 117.705 116.644 109.260 1.00 34.26  ? 289 ALA A CA    1 
ATOM 1724 C C     . ALA A 1 233 ? 117.572 115.479 110.232 1.00 34.26  ? 289 ALA A C     1 
ATOM 1725 O O     . ALA A 1 233 ? 118.572 114.855 110.596 1.00 34.26  ? 289 ALA A O     1 
ATOM 1726 C CB    . ALA A 1 233 ? 117.852 117.959 110.023 1.00 34.26  ? 289 ALA A CB    1 
ATOM 1727 N N     . LEU A 1 234 ? 116.344 115.179 110.668 1.00 33.84  ? 290 LEU A N     1 
ATOM 1728 C CA    . LEU A 1 234 ? 116.143 114.083 111.613 1.00 33.84  ? 290 LEU A CA    1 
ATOM 1729 C C     . LEU A 1 234 ? 116.234 112.717 110.944 1.00 33.84  ? 290 LEU A C     1 
ATOM 1730 O O     . LEU A 1 234 ? 116.569 111.732 111.610 1.00 33.84  ? 290 LEU A O     1 
ATOM 1731 C CB    . LEU A 1 234 ? 114.796 114.226 112.319 1.00 33.84  ? 290 LEU A CB    1 
ATOM 1732 C CG    . LEU A 1 234 ? 114.597 115.452 113.213 1.00 33.84  ? 290 LEU A CG    1 
ATOM 1733 C CD1   . LEU A 1 234 ? 113.120 115.793 113.343 1.00 33.84  ? 290 LEU A CD1   1 
ATOM 1734 C CD2   . LEU A 1 234 ? 115.216 115.230 114.585 1.00 33.84  ? 290 LEU A CD2   1 
ATOM 1735 N N     . LYS A 1 235 ? 115.912 112.624 109.659 1.00 33.23  ? 291 LYS A N     1 
ATOM 1736 C CA    . LYS A 1 235 ? 115.981 111.346 108.954 1.00 33.23  ? 291 LYS A CA    1 
ATOM 1737 C C     . LYS A 1 235 ? 117.384 110.785 109.099 1.00 33.23  ? 291 LYS A C     1 
ATOM 1738 O O     . LYS A 1 235 ? 117.564 109.658 109.563 1.00 33.23  ? 291 LYS A O     1 
ATOM 1739 C CB    . LYS A 1 235 ? 115.640 111.540 107.477 1.00 33.23  ? 291 LYS A CB    1 
ATOM 1740 C CG    . LYS A 1 235 ? 115.598 110.252 106.672 1.00 33.23  ? 291 LYS A CG    1 
ATOM 1741 C CD    . LYS A 1 235 ? 114.535 109.306 107.205 1.00 33.23  ? 291 LYS A CD    1 
ATOM 1742 C CE    . LYS A 1 235 ? 114.530 107.996 106.437 1.00 33.23  ? 291 LYS A CE    1 
ATOM 1743 N NZ    . LYS A 1 235 ? 114.272 108.207 104.986 1.00 33.23  ? 291 LYS A NZ    1 
ATOM 1744 N N     . GLU A 1 236 ? 118.379 111.563 108.702 1.00 31.09  ? 292 GLU A N     1 
ATOM 1745 C CA    . GLU A 1 236 ? 119.777 111.167 108.813 1.00 31.09  ? 292 GLU A CA    1 
ATOM 1746 C C     . GLU A 1 236 ? 120.313 111.785 110.096 1.00 31.09  ? 292 GLU A C     1 
ATOM 1747 O O     . GLU A 1 236 ? 120.962 112.829 110.092 1.00 31.09  ? 292 GLU A O     1 
ATOM 1748 C CB    . GLU A 1 236 ? 120.563 111.583 107.598 1.00 31.09  ? 292 GLU A CB    1 
ATOM 1749 C CG    . GLU A 1 236 ? 119.858 111.211 106.305 1.00 31.09  ? 292 GLU A CG    1 
ATOM 1750 C CD    . GLU A 1 236 ? 120.146 112.163 105.172 1.00 31.09  ? 292 GLU A CD    1 
ATOM 1751 O OE1   . GLU A 1 236 ? 120.696 113.253 105.425 1.00 31.09  ? 292 GLU A OE1   1 
ATOM 1752 O OE2   . GLU A 1 236 ? 119.826 111.813 104.015 1.00 31.09  ? 292 GLU A OE2   1 
ATOM 1753 N N     . ALA A 1 237 ? 120.024 111.120 111.205 1.00 30.15  ? 293 ALA A N     1 
ATOM 1754 C CA    . ALA A 1 237 ? 120.473 111.533 112.521 1.00 30.15  ? 293 ALA A CA    1 
ATOM 1755 C C     . ALA A 1 237 ? 121.458 110.497 113.026 1.00 30.15  ? 293 ALA A C     1 
ATOM 1756 O O     . ALA A 1 237 ? 121.263 109.296 112.814 1.00 30.15  ? 293 ALA A O     1 
ATOM 1757 C CB    . ALA A 1 237 ? 119.299 111.680 113.490 1.00 30.15  ? 293 ALA A CB    1 
ATOM 1758 N N     . ILE A 1 238 ? 122.491 110.955 113.718 1.00 28.50  ? 294 ILE A N     1 
ATOM 1759 C CA    . ILE A 1 238 ? 123.428 110.029 114.326 1.00 28.50  ? 294 ILE A CA    1 
ATOM 1760 C C     . ILE A 1 238 ? 123.116 110.143 115.804 1.00 28.50  ? 294 ILE A C     1 
ATOM 1761 O O     . ILE A 1 238 ? 123.649 111.013 116.490 1.00 28.50  ? 294 ILE A O     1 
ATOM 1762 C CB    . ILE A 1 238 ? 124.870 110.451 114.045 1.00 28.50  ? 294 ILE A CB    1 
ATOM 1763 C CG1   . ILE A 1 238 ? 125.069 110.712 112.553 1.00 28.50  ? 294 ILE A CG1   1 
ATOM 1764 C CG2   . ILE A 1 238 ? 125.820 109.372 114.501 1.00 28.50  ? 294 ILE A CG2   1 
ATOM 1765 C CD1   . ILE A 1 238 ? 126.498 111.037 112.185 1.00 28.50  ? 294 ILE A CD1   1 
ATOM 1766 N N     . PRO A 1 239 ? 122.242 109.249 116.349 1.00 27.46  ? 295 PRO A N     1 
ATOM 1767 C CA    . PRO A 1 239 ? 121.886 109.489 117.757 1.00 27.46  ? 295 PRO A CA    1 
ATOM 1768 C C     . PRO A 1 239 ? 122.798 108.900 118.827 1.00 27.46  ? 295 PRO A C     1 
ATOM 1769 O O     . PRO A 1 239 ? 123.339 107.809 118.648 1.00 27.46  ? 295 PRO A O     1 
ATOM 1770 C CB    . PRO A 1 239 ? 120.483 108.868 117.873 1.00 27.46  ? 295 PRO A CB    1 
ATOM 1771 C CG    . PRO A 1 239 ? 120.291 108.019 116.650 1.00 27.46  ? 295 PRO A CG    1 
ATOM 1772 C CD    . PRO A 1 239 ? 121.570 108.020 115.870 1.00 27.46  ? 295 PRO A CD    1 
ATOM 1773 N N     . ILE A 1 240 ? 122.969 109.620 119.933 1.00 26.00  ? 296 ILE A N     1 
ATOM 1774 C CA    . ILE A 1 240 ? 123.765 109.110 121.052 1.00 26.00  ? 296 ILE A CA    1 
ATOM 1775 C C     . ILE A 1 240 ? 122.951 109.331 122.323 1.00 26.00  ? 296 ILE A C     1 
ATOM 1776 O O     . ILE A 1 240 ? 122.356 110.392 122.482 1.00 26.00  ? 296 ILE A O     1 
ATOM 1777 C CB    . ILE A 1 240 ? 125.153 109.776 121.134 1.00 26.00  ? 296 ILE A CB    1 
ATOM 1778 C CG1   . ILE A 1 240 ? 125.127 111.168 120.515 1.00 26.00  ? 296 ILE A CG1   1 
ATOM 1779 C CG2   . ILE A 1 240 ? 126.175 108.960 120.367 1.00 26.00  ? 296 ILE A CG2   1 
ATOM 1780 C CD1   . ILE A 1 240 ? 126.436 111.914 120.644 1.00 26.00  ? 296 ILE A CD1   1 
ATOM 1781 N N     . ILE A 1 241 ? 122.862 108.352 123.201 1.00 30.00  ? 297 ILE A N     1 
ATOM 1782 C CA    . ILE A 1 241 ? 121.895 108.490 124.272 1.00 30.00  ? 297 ILE A CA    1 
ATOM 1783 C C     . ILE A 1 241 ? 122.563 108.467 125.639 1.00 30.00  ? 297 ILE A C     1 
ATOM 1784 O O     . ILE A 1 241 ? 122.986 107.415 126.128 1.00 30.00  ? 297 ILE A O     1 
ATOM 1785 C CB    . ILE A 1 241 ? 120.766 107.457 124.114 1.00 30.00  ? 297 ILE A CB    1 
ATOM 1786 C CG1   . ILE A 1 241 ? 119.902 107.365 125.373 1.00 30.00  ? 297 ILE A CG1   1 
ATOM 1787 C CG2   . ILE A 1 241 ? 121.352 106.126 123.695 1.00 30.00  ? 297 ILE A CG2   1 
ATOM 1788 C CD1   . ILE A 1 241 ? 118.759 106.382 125.248 1.00 30.00  ? 297 ILE A CD1   1 
ATOM 1789 N N     . VAL A 1 242 ? 122.701 109.643 126.243 1.00 28.12  ? 298 VAL A N     1 
ATOM 1790 C CA    . VAL A 1 242 ? 123.265 109.681 127.586 1.00 28.12  ? 298 VAL A CA    1 
ATOM 1791 C C     . VAL A 1 242 ? 122.097 109.414 128.519 1.00 28.12  ? 298 VAL A C     1 
ATOM 1792 O O     . VAL A 1 242 ? 121.094 110.118 128.460 1.00 28.12  ? 298 VAL A O     1 
ATOM 1793 C CB    . VAL A 1 242 ? 123.863 111.064 127.895 1.00 28.12  ? 298 VAL A CB    1 
ATOM 1794 C CG1   . VAL A 1 242 ? 124.852 110.973 129.043 1.00 28.12  ? 298 VAL A CG1   1 
ATOM 1795 C CG2   . VAL A 1 242 ? 124.548 111.632 126.663 1.00 28.12  ? 298 VAL A CG2   1 
ATOM 1796 N N     . THR A 1 243 ? 122.210 108.414 129.387 1.00 26.88  ? 299 THR A N     1 
ATOM 1797 C CA    . THR A 1 243 ? 121.076 108.047 130.238 1.00 26.88  ? 299 THR A CA    1 
ATOM 1798 C C     . THR A 1 243 ? 121.372 108.167 131.733 1.00 26.88  ? 299 THR A C     1 
ATOM 1799 O O     . THR A 1 243 ? 122.072 107.326 132.298 1.00 26.88  ? 299 THR A O     1 
ATOM 1800 C CB    . THR A 1 243 ? 120.607 106.608 129.929 1.00 26.88  ? 299 THR A CB    1 
ATOM 1801 O OG1   . THR A 1 243 ? 120.354 106.477 128.526 1.00 26.88  ? 299 THR A OG1   1 
ATOM 1802 C CG2   . THR A 1 243 ? 119.339 106.266 130.698 1.00 26.88  ? 299 THR A CG2   1 
ATOM 1803 N N     . ILE A 1 244 ? 120.837 109.204 132.377 1.00 24.08  ? 300 ILE A N     1 
ATOM 1804 C CA    . ILE A 1 244 ? 121.067 109.391 133.806 1.00 24.08  ? 300 ILE A CA    1 
ATOM 1805 C C     . ILE A 1 244 ? 119.799 108.995 134.538 1.00 24.08  ? 300 ILE A C     1 
ATOM 1806 O O     . ILE A 1 244 ? 118.778 109.674 134.416 1.00 24.08  ? 300 ILE A O     1 
ATOM 1807 C CB    . ILE A 1 244 ? 121.375 110.857 134.174 1.00 24.08  ? 300 ILE A CB    1 
ATOM 1808 C CG1   . ILE A 1 244 ? 122.473 111.435 133.285 1.00 24.08  ? 300 ILE A CG1   1 
ATOM 1809 C CG2   . ILE A 1 244 ? 121.773 110.972 135.638 1.00 24.08  ? 300 ILE A CG2   1 
ATOM 1810 C CD1   . ILE A 1 244 ? 123.286 112.523 133.951 1.00 24.08  ? 300 ILE A CD1   1 
ATOM 1811 N N     . GLY A 1 245 ? 119.846 107.901 135.291 1.00 23.23  ? 301 GLY A N     1 
ATOM 1812 C CA    . GLY A 1 245 ? 118.637 107.447 135.953 1.00 23.23  ? 301 GLY A CA    1 
ATOM 1813 C C     . GLY A 1 245 ? 117.603 106.968 134.960 1.00 23.23  ? 301 GLY A C     1 
ATOM 1814 O O     . GLY A 1 245 ? 117.902 106.223 134.021 1.00 23.23  ? 301 GLY A O     1 
ATOM 1815 N N     . LYS A 1 246 ? 116.365 107.401 135.165 1.00 26.80  ? 302 LYS A N     1 
ATOM 1816 C CA    . LYS A 1 246 ? 115.262 107.061 134.281 1.00 26.80  ? 302 LYS A CA    1 
ATOM 1817 C C     . LYS A 1 246 ? 115.112 108.047 133.134 1.00 26.80  ? 302 LYS A C     1 
ATOM 1818 O O     . LYS A 1 246 ? 114.156 107.936 132.360 1.00 26.80  ? 302 LYS A O     1 
ATOM 1819 C CB    . LYS A 1 246 ? 113.954 106.989 135.073 1.00 26.80  ? 302 LYS A CB    1 
ATOM 1820 C CG    . LYS A 1 246 ? 113.944 105.926 136.157 1.00 26.80  ? 302 LYS A CG    1 
ATOM 1821 C CD    . LYS A 1 246 ? 113.998 104.528 135.561 1.00 26.80  ? 302 LYS A CD    1 
ATOM 1822 C CE    . LYS A 1 246 ? 114.045 103.465 136.646 1.00 26.80  ? 302 LYS A CE    1 
ATOM 1823 N NZ    . LYS A 1 246 ? 112.767 103.388 137.406 1.00 26.80  ? 302 LYS A NZ    1 
ATOM 1824 N N     . ASP A 1 247 ? 116.026 109.002 133.009 1.00 26.53  ? 303 ASP A N     1 
ATOM 1825 C CA    . ASP A 1 247 ? 115.974 110.023 131.977 1.00 26.53  ? 303 ASP A CA    1 
ATOM 1826 C C     . ASP A 1 247 ? 117.062 109.774 130.942 1.00 26.53  ? 303 ASP A C     1 
ATOM 1827 O O     . ASP A 1 247 ? 118.132 109.249 131.258 1.00 26.53  ? 303 ASP A O     1 
ATOM 1828 C CB    . ASP A 1 247 ? 116.135 111.415 132.587 1.00 26.53  ? 303 ASP A CB    1 
ATOM 1829 C CG    . ASP A 1 247 ? 114.847 111.935 133.183 1.00 26.53  ? 303 ASP A CG    1 
ATOM 1830 O OD1   . ASP A 1 247 ? 113.769 111.548 132.688 1.00 26.53  ? 303 ASP A OD1   1 
ATOM 1831 O OD2   . ASP A 1 247 ? 114.904 112.715 134.151 1.00 26.53  ? 303 ASP A OD2   1 
ATOM 1832 N N     . TRP A 1 248 ? 116.760 110.193 129.715 1.00 27.40  ? 304 TRP A N     1 
ATOM 1833 C CA    . TRP A 1 248 ? 117.693 109.998 128.623 1.00 27.40  ? 304 TRP A CA    1 
ATOM 1834 C C     . TRP A 1 248 ? 117.772 111.217 127.726 1.00 27.40  ? 304 TRP A C     1 
ATOM 1835 O O     . TRP A 1 248 ? 116.771 111.904 127.513 1.00 27.40  ? 304 TRP A O     1 
ATOM 1836 C CB    . TRP A 1 248 ? 117.284 108.770 127.805 1.00 27.40  ? 304 TRP A CB    1 
ATOM 1837 C CG    . TRP A 1 248 ? 115.797 108.620 127.630 1.00 27.40  ? 304 TRP A CG    1 
ATOM 1838 C CD1   . TRP A 1 248 ? 114.943 107.926 128.439 1.00 27.40  ? 304 TRP A CD1   1 
ATOM 1839 C CD2   . TRP A 1 248 ? 114.992 109.173 126.580 1.00 27.40  ? 304 TRP A CD2   1 
ATOM 1840 N NE1   . TRP A 1 248 ? 113.660 108.016 127.961 1.00 27.40  ? 304 TRP A NE1   1 
ATOM 1841 C CE2   . TRP A 1 248 ? 113.662 108.775 126.821 1.00 27.40  ? 304 TRP A CE2   1 
ATOM 1842 C CE3   . TRP A 1 248 ? 115.264 109.965 125.462 1.00 27.40  ? 304 TRP A CE3   1 
ATOM 1843 C CZ2   . TRP A 1 248 ? 112.611 109.141 125.986 1.00 27.40  ? 304 TRP A CZ2   1 
ATOM 1844 C CZ3   . TRP A 1 248 ? 114.221 110.329 124.638 1.00 27.40  ? 304 TRP A CZ3   1 
ATOM 1845 C CH2   . TRP A 1 248 ? 112.911 109.918 124.902 1.00 27.40  ? 304 TRP A CH2   1 
ATOM 1846 N N     . ILE A 1 249 ? 118.956 111.508 127.219 1.00 27.15  ? 305 ILE A N     1 
ATOM 1847 C CA    . ILE A 1 249 ? 119.180 112.616 126.298 1.00 27.15  ? 305 ILE A CA    1 
ATOM 1848 C C     . ILE A 1 249 ? 119.665 112.007 124.991 1.00 27.15  ? 305 ILE A C     1 
ATOM 1849 O O     . ILE A 1 249 ? 120.787 111.489 124.920 1.00 27.15  ? 305 ILE A O     1 
ATOM 1850 C CB    . ILE A 1 249 ? 120.201 113.625 126.857 1.00 30.00  ? 305 ILE A CB    1 
ATOM 1851 C CG1   . ILE A 1 249 ? 119.620 114.355 128.070 1.00 30.00  ? 305 ILE A CG1   1 
ATOM 1852 C CG2   . ILE A 1 249 ? 120.615 114.616 125.781 1.00 30.00  ? 305 ILE A CG2   1 
ATOM 1853 C CD1   . ILE A 1 249 ? 120.638 115.167 128.838 1.00 30.00  ? 305 ILE A CD1   1 
ATOM 1854 N N     . VAL A 1 250 ? 118.825 112.047 123.964 1.00 24.69  ? 306 VAL A N     1 
ATOM 1855 C CA    . VAL A 1 250 ? 119.195 111.552 122.644 1.00 24.69  ? 306 VAL A CA    1 
ATOM 1856 C C     . VAL A 1 250 ? 119.742 112.725 121.848 1.00 24.69  ? 306 VAL A C     1 
ATOM 1857 O O     . VAL A 1 250 ? 119.064 113.745 121.680 1.00 24.69  ? 306 VAL A O     1 
ATOM 1858 C CB    . VAL A 1 250 ? 118.005 110.902 121.929 1.00 24.69  ? 306 VAL A CB    1 
ATOM 1859 C CG1   . VAL A 1 250 ? 118.353 110.640 120.474 1.00 24.69  ? 306 VAL A CG1   1 
ATOM 1860 C CG2   . VAL A 1 250 ? 117.618 109.610 122.623 1.00 24.69  ? 306 VAL A CG2   1 
ATOM 1861 N N     . MET A 1 251 ? 120.957 112.581 121.358 1.00 24.06  ? 307 MET A N     1 
ATOM 1862 C CA    . MET A 1 251 ? 121.738 113.689 120.845 1.00 24.06  ? 307 MET A CA    1 
ATOM 1863 C C     . MET A 1 251 ? 121.875 113.534 119.334 1.00 24.06  ? 307 MET A C     1 
ATOM 1864 O O     . MET A 1 251 ? 121.275 112.649 118.719 1.00 24.06  ? 307 MET A O     1 
ATOM 1865 C CB    . MET A 1 251 ? 123.097 113.709 121.536 1.00 24.06  ? 307 MET A CB    1 
ATOM 1866 C CG    . MET A 1 251 ? 123.206 114.649 122.708 1.00 24.06  ? 307 MET A CG    1 
ATOM 1867 S SD    . MET A 1 251 ? 124.812 114.428 123.479 1.00 24.06  ? 307 MET A SD    1 
ATOM 1868 C CE    . MET A 1 251 ? 124.513 115.168 125.070 1.00 24.06  ? 307 MET A CE    1 
ATOM 1869 N N     . ASP A 1 252 ? 122.676 114.404 118.730 1.00 26.96  ? 308 ASP A N     1 
ATOM 1870 C CA    . ASP A 1 252 ? 122.892 114.396 117.285 1.00 26.96  ? 308 ASP A CA    1 
ATOM 1871 C C     . ASP A 1 252 ? 124.387 114.557 117.038 1.00 26.96  ? 308 ASP A C     1 
ATOM 1872 O O     . ASP A 1 252 ? 124.913 115.673 117.088 1.00 26.96  ? 308 ASP A O     1 
ATOM 1873 C CB    . ASP A 1 252 ? 122.096 115.502 116.611 1.00 26.96  ? 308 ASP A CB    1 
ATOM 1874 C CG    . ASP A 1 252 ? 121.953 115.294 115.126 1.00 26.96  ? 308 ASP A CG    1 
ATOM 1875 O OD1   . ASP A 1 252 ? 122.144 114.150 114.664 1.00 26.96  ? 308 ASP A OD1   1 
ATOM 1876 O OD2   . ASP A 1 252 ? 121.646 116.274 114.415 1.00 26.96  ? 308 ASP A OD2   1 
ATOM 1877 N N     . ALA A 1 253 ? 125.066 113.449 116.751 1.00 28.27  ? 309 ALA A N     1 
ATOM 1878 C CA    . ALA A 1 253 ? 126.518 113.465 116.654 1.00 28.27  ? 309 ALA A CA    1 
ATOM 1879 C C     . ALA A 1 253 ? 127.027 114.174 115.413 1.00 28.27  ? 309 ALA A C     1 
ATOM 1880 O O     . ALA A 1 253 ? 128.246 114.291 115.256 1.00 28.27  ? 309 ALA A O     1 
ATOM 1881 C CB    . ALA A 1 253 ? 127.066 112.039 116.693 1.00 28.27  ? 309 ALA A CB    1 
ATOM 1882 N N     . ARG A 1 254 ? 126.135 114.633 114.538 1.00 28.62  ? 310 ARG A N     1 
ATOM 1883 C CA    . ARG A 1 254 ? 126.549 115.309 113.306 1.00 28.62  ? 310 ARG A CA    1 
ATOM 1884 C C     . ARG A 1 254 ? 127.390 116.532 113.618 1.00 28.62  ? 310 ARG A C     1 
ATOM 1885 O O     . ARG A 1 254 ? 128.353 116.814 112.908 1.00 28.62  ? 310 ARG A O     1 
ATOM 1886 C CB    . ARG A 1 254 ? 125.345 115.644 112.435 1.00 28.62  ? 310 ARG A CB    1 
ATOM 1887 C CG    . ARG A 1 254 ? 124.708 114.402 111.843 1.00 28.62  ? 310 ARG A CG    1 
ATOM 1888 C CD    . ARG A 1 254 ? 123.551 114.747 110.935 1.00 28.62  ? 310 ARG A CD    1 
ATOM 1889 N NE    . ARG A 1 254 ? 122.500 115.448 111.655 1.00 28.62  ? 310 ARG A NE    1 
ATOM 1890 C CZ    . ARG A 1 254 ? 121.399 115.915 111.084 1.00 28.62  ? 310 ARG A CZ    1 
ATOM 1891 N NH1   . ARG A 1 254 ? 121.210 115.758 109.781 1.00 28.62  ? 310 ARG A NH1   1 
ATOM 1892 N NH2   . ARG A 1 254 ? 120.491 116.544 111.815 1.00 28.62  ? 310 ARG A NH2   1 
ATOM 1893 N N     . GLY A 1 255 ? 127.029 117.280 114.653 1.00 28.15  ? 311 GLY A N     1 
ATOM 1894 C CA    . GLY A 1 255 ? 127.859 118.387 115.088 1.00 28.15  ? 311 GLY A CA    1 
ATOM 1895 C C     . GLY A 1 255 ? 129.237 117.938 115.511 1.00 28.15  ? 311 GLY A C     1 
ATOM 1896 O O     . GLY A 1 255 ? 130.223 118.635 115.264 1.00 28.15  ? 311 GLY A O     1 
ATOM 1897 N N     . LEU A 1 256 ? 129.326 116.773 116.157 1.00 29.14  ? 312 LEU A N     1 
ATOM 1898 C CA    . LEU A 1 256 ? 130.616 116.178 116.479 1.00 29.14  ? 312 LEU A CA    1 
ATOM 1899 C C     . LEU A 1 256 ? 131.326 115.667 115.243 1.00 29.14  ? 312 LEU A C     1 
ATOM 1900 O O     . LEU A 1 256 ? 132.558 115.720 115.170 1.00 29.14  ? 312 LEU A O     1 
ATOM 1901 C CB    . LEU A 1 256 ? 130.438 115.033 117.469 1.00 29.14  ? 312 LEU A CB    1 
ATOM 1902 C CG    . LEU A 1 256 ? 130.100 115.438 118.892 1.00 29.14  ? 312 LEU A CG    1 
ATOM 1903 C CD1   . LEU A 1 256 ? 129.748 114.218 119.719 1.00 29.14  ? 312 LEU A CD1   1 
ATOM 1904 C CD2   . LEU A 1 256 ? 131.292 116.171 119.481 1.00 29.14  ? 312 LEU A CD2   1 
ATOM 1905 N N     . LEU A 1 257 ? 130.568 115.163 114.275 1.00 30.52  ? 313 LEU A N     1 
ATOM 1906 C CA    . LEU A 1 257 ? 131.173 114.675 113.046 1.00 30.52  ? 313 LEU A CA    1 
ATOM 1907 C C     . LEU A 1 257 ? 131.845 115.817 112.291 1.00 30.52  ? 313 LEU A C     1 
ATOM 1908 O O     . LEU A 1 257 ? 132.971 115.675 111.794 1.00 30.52  ? 313 LEU A O     1 
ATOM 1909 C CB    . LEU A 1 257 ? 130.095 114.000 112.201 1.00 30.52  ? 313 LEU A CB    1 
ATOM 1910 C CG    . LEU A 1 257 ? 130.478 113.252 110.936 1.00 30.52  ? 313 LEU A CG    1 
ATOM 1911 C CD1   . LEU A 1 257 ? 131.348 112.072 111.324 1.00 30.52  ? 313 LEU A CD1   1 
ATOM 1912 C CD2   . LEU A 1 257 ? 129.246 112.789 110.186 1.00 30.52  ? 313 LEU A CD2   1 
ATOM 1913 N N     . ARG A 1 258 ? 131.182 116.972 112.234 1.00 30.09  ? 314 ARG A N     1 
ATOM 1914 C CA    . ARG A 1 258 ? 131.742 118.115 111.529 1.00 30.09  ? 314 ARG A CA    1 
ATOM 1915 C C     . ARG A 1 258 ? 133.044 118.573 112.171 1.00 30.09  ? 314 ARG A C     1 
ATOM 1916 O O     . ARG A 1 258 ? 134.002 118.917 111.467 1.00 30.09  ? 314 ARG A O     1 
ATOM 1917 C CB    . ARG A 1 258 ? 130.725 119.254 111.496 1.00 30.09  ? 314 ARG A CB    1 
ATOM 1918 C CG    . ARG A 1 258 ? 130.912 120.220 110.338 1.00 30.09  ? 314 ARG A CG    1 
ATOM 1919 C CD    . ARG A 1 258 ? 130.305 121.576 110.631 1.00 30.09  ? 314 ARG A CD    1 
ATOM 1920 N NE    . ARG A 1 258 ? 131.270 122.500 111.214 1.00 30.09  ? 314 ARG A NE    1 
ATOM 1921 C CZ    . ARG A 1 258 ? 131.017 123.306 112.234 1.00 30.09  ? 314 ARG A CZ    1 
ATOM 1922 N NH1   . ARG A 1 258 ? 129.826 123.352 112.800 1.00 30.09  ? 314 ARG A NH1   1 
ATOM 1923 N NH2   . ARG A 1 258 ? 131.989 124.080 112.704 1.00 30.09  ? 314 ARG A NH2   1 
ATOM 1924 N N     . ALA A 1 259 ? 133.096 118.584 113.504 1.00 28.35  ? 315 ALA A N     1 
ATOM 1925 C CA    . ALA A 1 259 ? 134.267 119.109 114.191 1.00 28.35  ? 315 ALA A CA    1 
ATOM 1926 C C     . ALA A 1 259 ? 135.505 118.281 113.881 1.00 28.35  ? 315 ALA A C     1 
ATOM 1927 O O     . ALA A 1 259 ? 136.572 118.833 113.592 1.00 28.35  ? 315 ALA A O     1 
ATOM 1928 C CB    . ALA A 1 259 ? 134.012 119.163 115.695 1.00 28.35  ? 315 ALA A CB    1 
ATOM 1929 N N     . VAL A 1 260 ? 135.379 116.954 113.915 1.00 28.76  ? 316 VAL A N     1 
ATOM 1930 C CA    . VAL A 1 260 ? 136.518 116.116 113.566 1.00 28.76  ? 316 VAL A CA    1 
ATOM 1931 C C     . VAL A 1 260 ? 136.824 116.214 112.079 1.00 28.76  ? 316 VAL A C     1 
ATOM 1932 O O     . VAL A 1 260 ? 137.987 116.097 111.678 1.00 28.76  ? 316 VAL A O     1 
ATOM 1933 C CB    . VAL A 1 260 ? 136.285 114.660 114.006 1.00 28.76  ? 316 VAL A CB    1 
ATOM 1934 C CG1   . VAL A 1 260 ? 136.348 114.551 115.517 1.00 28.76  ? 316 VAL A CG1   1 
ATOM 1935 C CG2   . VAL A 1 260 ? 134.961 114.171 113.511 1.00 28.76  ? 316 VAL A CG2   1 
ATOM 1936 N N     . TYR A 1 261 ? 135.809 116.461 111.256 1.00 28.90  ? 317 TYR A N     1 
ATOM 1937 C CA    . TYR A 1 261 ? 136.013 116.533 109.808 1.00 28.90  ? 317 TYR A CA    1 
ATOM 1938 C C     . TYR A 1 261 ? 136.820 117.748 109.381 1.00 28.90  ? 317 TYR A C     1 
ATOM 1939 O O     . TYR A 1 261 ? 137.734 117.627 108.564 1.00 28.90  ? 317 TYR A O     1 
ATOM 1940 C CB    . TYR A 1 261 ? 134.675 116.526 109.064 1.00 28.90  ? 317 TYR A CB    1 
ATOM 1941 C CG    . TYR A 1 261 ? 134.187 115.148 108.685 1.00 28.90  ? 317 TYR A CG    1 
ATOM 1942 C CD1   . TYR A 1 261 ? 132.980 114.978 108.023 1.00 28.90  ? 317 TYR A CD1   1 
ATOM 1943 C CD2   . TYR A 1 261 ? 134.935 114.018 108.984 1.00 28.90  ? 317 TYR A CD2   1 
ATOM 1944 C CE1   . TYR A 1 261 ? 132.531 113.721 107.671 1.00 28.90  ? 317 TYR A CE1   1 
ATOM 1945 C CE2   . TYR A 1 261 ? 134.493 112.756 108.637 1.00 28.90  ? 317 TYR A CE2   1 
ATOM 1946 C CZ    . TYR A 1 261 ? 133.290 112.614 107.980 1.00 28.90  ? 317 TYR A CZ    1 
ATOM 1947 O OH    . TYR A 1 261 ? 132.842 111.360 107.631 1.00 28.90  ? 317 TYR A OH    1 
ATOM 1948 N N     . TRP A 1 262 ? 136.496 118.918 109.922 1.00 28.61  ? 318 TRP A N     1 
ATOM 1949 C CA    . TRP A 1 262 ? 137.174 120.133 109.492 1.00 28.61  ? 318 TRP A CA    1 
ATOM 1950 C C     . TRP A 1 262 ? 138.430 120.443 110.293 1.00 28.61  ? 318 TRP A C     1 
ATOM 1951 O O     . TRP A 1 262 ? 139.155 121.375 109.933 1.00 28.61  ? 318 TRP A O     1 
ATOM 1952 C CB    . TRP A 1 262 ? 136.218 121.333 109.529 1.00 28.61  ? 318 TRP A CB    1 
ATOM 1953 C CG    . TRP A 1 262 ? 136.014 121.966 110.869 1.00 28.61  ? 318 TRP A CG    1 
ATOM 1954 C CD1   . TRP A 1 262 ? 135.069 121.635 111.786 1.00 28.61  ? 318 TRP A CD1   1 
ATOM 1955 C CD2   . TRP A 1 262 ? 136.757 123.056 111.436 1.00 28.61  ? 318 TRP A CD2   1 
ATOM 1956 N NE1   . TRP A 1 262 ? 135.177 122.438 112.891 1.00 28.61  ? 318 TRP A NE1   1 
ATOM 1957 C CE2   . TRP A 1 262 ? 136.206 123.320 112.701 1.00 28.61  ? 318 TRP A CE2   1 
ATOM 1958 C CE3   . TRP A 1 262 ? 137.833 123.831 110.997 1.00 28.61  ? 318 TRP A CE3   1 
ATOM 1959 C CZ2   . TRP A 1 262 ? 136.693 124.320 113.533 1.00 28.61  ? 318 TRP A CZ2   1 
ATOM 1960 C CZ3   . TRP A 1 262 ? 138.319 124.825 111.828 1.00 28.61  ? 318 TRP A CZ3   1 
ATOM 1961 C CH2   . TRP A 1 262 ? 137.748 125.060 113.079 1.00 28.61  ? 318 TRP A CH2   1 
ATOM 1962 N N     . ARG A 1 263 ? 138.731 119.680 111.342 1.00 29.95  ? 319 ARG A N     1 
ATOM 1963 C CA    . ARG A 1 263 ? 139.909 119.942 112.157 1.00 29.95  ? 319 ARG A CA    1 
ATOM 1964 C C     . ARG A 1 263 ? 141.061 118.989 111.849 1.00 29.95  ? 319 ARG A C     1 
ATOM 1965 O O     . ARG A 1 263 ? 142.005 118.888 112.640 1.00 29.95  ? 319 ARG A O     1 
ATOM 1966 C CB    . ARG A 1 263 ? 139.554 119.895 113.641 1.00 29.95  ? 319 ARG A CB    1 
ATOM 1967 C CG    . ARG A 1 263 ? 138.670 121.046 114.079 1.00 29.95  ? 319 ARG A CG    1 
ATOM 1968 C CD    . ARG A 1 263 ? 138.497 121.075 115.583 1.00 29.95  ? 319 ARG A CD    1 
ATOM 1969 N NE    . ARG A 1 263 ? 139.535 121.876 116.217 1.00 29.95  ? 319 ARG A NE    1 
ATOM 1970 C CZ    . ARG A 1 263 ? 139.335 123.076 116.739 1.00 29.95  ? 319 ARG A CZ    1 
ATOM 1971 N NH1   . ARG A 1 263 ? 138.141 123.642 116.730 1.00 29.95  ? 319 ARG A NH1   1 
ATOM 1972 N NH2   . ARG A 1 263 ? 140.359 123.726 117.283 1.00 29.95  ? 319 ARG A NH2   1 
ATOM 1973 N N     . GLY A 1 264 ? 141.007 118.294 110.713 1.00 29.00  ? 320 GLY A N     1 
ATOM 1974 C CA    . GLY A 1 264 ? 142.123 117.490 110.248 1.00 29.00  ? 320 GLY A CA    1 
ATOM 1975 C C     . GLY A 1 264 ? 142.503 116.325 111.138 1.00 29.00  ? 320 GLY A C     1 
ATOM 1976 O O     . GLY A 1 264 ? 143.686 116.111 111.414 1.00 29.00  ? 320 GLY A O     1 
ATOM 1977 N N     . ILE A 1 265 ? 141.512 115.563 111.591 1.00 29.34  ? 321 ILE A N     1 
ATOM 1978 C CA    . ILE A 1 265 ? 141.732 114.405 112.453 1.00 29.34  ? 321 ILE A CA    1 
ATOM 1979 C C     . ILE A 1 265 ? 141.393 113.103 111.731 1.00 29.34  ? 321 ILE A C     1 
ATOM 1980 O O     . ILE A 1 265 ? 142.228 112.201 111.636 1.00 29.34  ? 321 ILE A O     1 
ATOM 1981 C CB    . ILE A 1 265 ? 140.942 114.537 113.774 1.00 29.34  ? 321 ILE A CB    1 
ATOM 1982 C CG1   . ILE A 1 265 ? 141.487 115.698 114.603 1.00 29.34  ? 321 ILE A CG1   1 
ATOM 1983 C CG2   . ILE A 1 265 ? 141.016 113.248 114.565 1.00 29.34  ? 321 ILE A CG2   1 
ATOM 1984 C CD1   . ILE A 1 265 ? 140.618 116.066 115.782 1.00 29.34  ? 321 ILE A CD1   1 
ATOM 1985 N N     . ALA A 1 266 ? 140.172 112.986 111.213 1.00 29.74  ? 322 ALA A N     1 
ATOM 1986 C CA    . ALA A 1 266 ? 139.748 111.794 110.488 1.00 29.74  ? 322 ALA A CA    1 
ATOM 1987 C C     . ALA A 1 266 ? 139.093 112.206 109.181 1.00 29.74  ? 322 ALA A C     1 
ATOM 1988 O O     . ALA A 1 266 ? 138.229 113.087 109.171 1.00 29.74  ? 322 ALA A O     1 
ATOM 1989 C CB    . ALA A 1 266 ? 138.779 110.953 111.324 1.00 29.74  ? 322 ALA A CB    1 
ATOM 1990 N N     . LYS A 1 267 ? 139.536 111.583 108.086 1.00 31.77  ? 323 LYS A N     1 
ATOM 1991 C CA    . LYS A 1 267 ? 138.999 111.893 106.763 1.00 31.77  ? 323 LYS A CA    1 
ATOM 1992 C C     . LYS A 1 267 ? 138.157 110.759 106.229 1.00 31.77  ? 323 LYS A C     1 
ATOM 1993 O O     . LYS A 1 267 ? 138.658 109.894 105.510 1.00 31.77  ? 323 LYS A O     1 
ATOM 1994 C CB    . LYS A 1 267 ? 140.126 112.156 105.776 1.00 31.77  ? 323 LYS A CB    1 
ATOM 1995 C CG    . LYS A 1 267 ? 140.798 113.504 105.908 1.00 31.77  ? 323 LYS A CG    1 
ATOM 1996 C CD    . LYS A 1 267 ? 141.385 113.849 104.558 1.00 31.77  ? 323 LYS A CD    1 
ATOM 1997 C CE    . LYS A 1 267 ? 141.578 112.574 103.750 1.00 31.77  ? 323 LYS A CE    1 
ATOM 1998 N NZ    . LYS A 1 267 ? 141.733 112.831 102.292 1.00 31.77  ? 323 LYS A NZ    1 
ATOM 1999 N N     . PRO A 1 268 ? 136.883 110.755 106.572 1.00 28.86  ? 324 PRO A N     1 
ATOM 2000 C CA    . PRO A 1 268 ? 135.961 109.743 106.106 1.00 28.86  ? 324 PRO A CA    1 
ATOM 2001 C C     . PRO A 1 268 ? 136.187 108.357 106.659 1.00 28.86  ? 324 PRO A C     1 
ATOM 2002 O O     . PRO A 1 268 ? 135.737 107.385 106.047 1.00 28.86  ? 324 PRO A O     1 
ATOM 2003 N N     . GLY A 1 269 ? 136.870 108.225 107.794 1.00 32.41  ? 325 GLY A N     1 
ATOM 2004 C CA    . GLY A 1 269 ? 137.151 106.921 108.394 1.00 32.41  ? 325 GLY A CA    1 
ATOM 2005 C C     . GLY A 1 269 ? 136.898 106.987 109.899 1.00 32.41  ? 325 GLY A C     1 
ATOM 2006 O O     . GLY A 1 269 ? 137.766 107.431 110.656 1.00 32.41  ? 325 GLY A O     1 
ATOM 2007 N N     . LEU A 1 270 ? 135.698 106.591 110.325 1.00 33.57  ? 326 LEU A N     1 
ATOM 2008 C CA    . LEU A 1 270 ? 135.340 106.589 111.751 1.00 33.57  ? 326 LEU A CA    1 
ATOM 2009 C C     . LEU A 1 270 ? 133.973 105.941 111.915 1.00 33.57  ? 326 LEU A C     1 
ATOM 2010 O O     . LEU A 1 270 ? 133.248 105.769 110.939 1.00 33.57  ? 326 LEU A O     1 
ATOM 2011 C CB    . LEU A 1 270 ? 135.338 108.006 112.348 1.00 33.57  ? 326 LEU A CB    1 
ATOM 2012 C CG    . LEU A 1 270 ? 134.517 109.104 111.670 1.00 33.57  ? 326 LEU A CG    1 
ATOM 2013 C CD1   . LEU A 1 270 ? 133.134 109.145 112.283 1.00 33.57  ? 326 LEU A CD1   1 
ATOM 2014 C CD2   . LEU A 1 270 ? 135.191 110.452 111.852 1.00 33.57  ? 326 LEU A CD2   1 
ATOM 2015 N N     . SER A 1 271 ? 133.609 105.600 113.144 1.00 34.40  ? 327 SER A N     1 
ATOM 2016 C CA    . SER A 1 271 ? 132.328 104.949 113.397 1.00 34.40  ? 327 SER A CA    1 
ATOM 2017 C C     . SER A 1 271 ? 131.817 105.449 114.728 1.00 34.40  ? 327 SER A C     1 
ATOM 2018 O O     . SER A 1 271 ? 132.517 106.209 115.390 1.00 34.40  ? 327 SER A O     1 
ATOM 2019 C CB    . SER A 1 271 ? 132.543 103.448 113.475 1.00 34.40  ? 327 SER A CB    1 
ATOM 2020 O OG    . SER A 1 271 ? 133.447 103.124 114.518 1.00 34.40  ? 327 SER A OG    1 
ATOM 2021 N N     . LEU A 1 272 ? 130.616 105.043 115.147 1.00 33.13  ? 328 LEU A N     1 
ATOM 2022 C CA    . LEU A 1 272 ? 130.196 105.456 116.485 1.00 33.13  ? 328 LEU A CA    1 
ATOM 2023 C C     . LEU A 1 272 ? 130.838 104.575 117.550 1.00 33.13  ? 328 LEU A C     1 
ATOM 2024 O O     . LEU A 1 272 ? 130.195 104.101 118.482 1.00 33.13  ? 328 LEU A O     1 
ATOM 2025 C CB    . LEU A 1 272 ? 128.678 105.430 116.608 1.00 33.13  ? 328 LEU A CB    1 
ATOM 2026 C CG    . LEU A 1 272 ? 127.914 106.649 116.105 1.00 33.13  ? 328 LEU A CG    1 
ATOM 2027 C CD1   . LEU A 1 272 ? 128.326 107.888 116.881 1.00 33.13  ? 328 LEU A CD1   1 
ATOM 2028 C CD2   . LEU A 1 272 ? 128.105 106.843 114.615 1.00 33.13  ? 328 LEU A CD2   1 
ATOM 2029 N N     . LYS A 1 273 ? 132.120 104.352 117.395 1.00 34.08  ? 329 LYS A N     1 
ATOM 2030 C CA    . LYS A 1 273 ? 133.026 103.859 118.419 1.00 34.08  ? 329 LYS A CA    1 
ATOM 2031 C C     . LYS A 1 273 ? 134.290 104.693 118.482 1.00 34.08  ? 329 LYS A C     1 
ATOM 2032 O O     . LYS A 1 273 ? 134.798 104.957 119.574 1.00 34.08  ? 329 LYS A O     1 
ATOM 2033 C CB    . LYS A 1 273 ? 133.381 102.384 118.163 1.00 34.08  ? 329 LYS A CB    1 
ATOM 2034 C CG    . LYS A 1 273 ? 134.421 101.814 119.116 1.00 34.08  ? 329 LYS A CG    1 
ATOM 2035 C CD    . LYS A 1 273 ? 134.795 100.390 118.738 1.00 34.08  ? 329 LYS A CD    1 
ATOM 2036 C CE    . LYS A 1 273 ? 135.794 99.803  119.722 1.00 34.08  ? 329 LYS A CE    1 
ATOM 2037 N NZ    . LYS A 1 273 ? 135.278 99.826  121.119 1.00 34.08  ? 329 LYS A NZ    1 
ATOM 2038 N N     . GLU A 1 274 ? 134.799 105.128 117.333 1.00 32.63  ? 330 GLU A N     1 
ATOM 2039 C CA    . GLU A 1 274 ? 135.979 105.973 117.288 1.00 32.63  ? 330 GLU A CA    1 
ATOM 2040 C C     . GLU A 1 274 ? 135.621 107.442 117.330 1.00 32.63  ? 330 GLU A C     1 
ATOM 2041 O O     . GLU A 1 274 ? 136.405 108.246 117.845 1.00 32.63  ? 330 GLU A O     1 
ATOM 2042 C CB    . GLU A 1 274 ? 136.797 105.681 116.029 1.00 32.63  ? 330 GLU A CB    1 
ATOM 2043 C CG    . GLU A 1 274 ? 137.397 104.285 115.991 1.00 32.63  ? 330 GLU A CG    1 
ATOM 2044 C CD    . GLU A 1 274 ? 138.127 103.998 114.694 1.00 32.63  ? 330 GLU A CD    1 
ATOM 2045 O OE1   . GLU A 1 274 ? 138.075 104.848 113.780 1.00 32.63  ? 330 GLU A OE1   1 
ATOM 2046 O OE2   . GLU A 1 274 ? 138.754 102.923 114.588 1.00 32.63  ? 330 GLU A OE2   1 
ATOM 2047 N N     . LEU A 1 275 ? 134.445 107.805 116.811 1.00 31.65  ? 331 LEU A N     1 
ATOM 2048 C CA    . LEU A 1 275 ? 134.002 109.193 116.869 1.00 31.65  ? 331 LEU A CA    1 
ATOM 2049 C C     . LEU A 1 275 ? 133.914 109.669 118.314 1.00 31.65  ? 331 LEU A C     1 
ATOM 2050 O O     . LEU A 1 275 ? 134.638 110.581 118.729 1.00 31.65  ? 331 LEU A O     1 
ATOM 2051 C CB    . LEU A 1 275 ? 132.655 109.336 116.162 1.00 31.65  ? 331 LEU A CB    1 
ATOM 2052 C CG    . LEU A 1 275 ? 132.149 110.755 115.936 1.00 31.65  ? 331 LEU A CG    1 
ATOM 2053 C CD1   . LEU A 1 275 ? 133.172 111.543 115.154 1.00 31.65  ? 331 LEU A CD1   1 
ATOM 2054 C CD2   . LEU A 1 275 ? 130.813 110.736 115.213 1.00 31.65  ? 331 LEU A CD2   1 
ATOM 2055 N N     . LEU A 1 276 ? 133.075 109.001 119.099 1.00 29.23  ? 332 LEU A N     1 
ATOM 2056 C CA    . LEU A 1 276 ? 132.948 109.344 120.512 1.00 29.23  ? 332 LEU A CA    1 
ATOM 2057 C C     . LEU A 1 276 ? 134.269 109.187 121.245 1.00 29.23  ? 332 LEU A C     1 
ATOM 2058 O O     . LEU A 1 276 ? 134.463 109.788 122.294 1.00 29.23  ? 332 LEU A O     1 
ATOM 2059 C CB    . LEU A 1 276 ? 131.878 108.479 121.169 1.00 29.23  ? 332 LEU A CB    1 
ATOM 2060 C CG    . LEU A 1 276 ? 130.472 108.764 120.651 1.00 29.23  ? 332 LEU A CG    1 
ATOM 2061 C CD1   . LEU A 1 276 ? 129.478 107.791 121.258 1.00 29.23  ? 332 LEU A CD1   1 
ATOM 2062 C CD2   . LEU A 1 276 ? 130.096 110.201 120.973 1.00 29.23  ? 332 LEU A CD2   1 
ATOM 2063 N N     . GLY A 1 277 ? 135.174 108.376 120.707 1.00 28.53  ? 333 GLY A N     1 
ATOM 2064 C CA    . GLY A 1 277 ? 136.482 108.221 121.318 1.00 28.53  ? 333 GLY A CA    1 
ATOM 2065 C C     . GLY A 1 277 ? 137.299 109.498 121.292 1.00 28.53  ? 333 GLY A C     1 
ATOM 2066 O O     . GLY A 1 277 ? 138.078 109.765 122.209 1.00 28.53  ? 333 GLY A O     1 
ATOM 2067 N N     . PHE A 1 278 ? 137.148 110.294 120.236 1.00 28.89  ? 334 PHE A N     1 
ATOM 2068 C CA    . PHE A 1 278 ? 137.806 111.594 120.182 1.00 28.89  ? 334 PHE A CA    1 
ATOM 2069 C C     . PHE A 1 278 ? 137.317 112.551 121.258 1.00 28.89  ? 334 PHE A C     1 
ATOM 2070 O O     . PHE A 1 278 ? 138.054 113.475 121.619 1.00 28.89  ? 334 PHE A O     1 
ATOM 2071 C CB    . PHE A 1 278 ? 137.592 112.238 118.811 1.00 28.89  ? 334 PHE A CB    1 
ATOM 2072 C CG    . PHE A 1 278 ? 138.138 111.438 117.669 1.00 28.89  ? 334 PHE A CG    1 
ATOM 2073 C CD1   . PHE A 1 278 ? 139.499 111.267 117.516 1.00 28.89  ? 334 PHE A CD1   1 
ATOM 2074 C CD2   . PHE A 1 278 ? 137.289 110.845 116.761 1.00 28.89  ? 334 PHE A CD2   1 
ATOM 2075 C CE1   . PHE A 1 278 ? 139.998 110.533 116.475 1.00 28.89  ? 334 PHE A CE1   1 
ATOM 2076 C CE2   . PHE A 1 278 ? 137.785 110.106 115.721 1.00 28.89  ? 334 PHE A CE2   1 
ATOM 2077 C CZ    . PHE A 1 278 ? 139.141 109.949 115.577 1.00 28.89  ? 334 PHE A CZ    1 
ATOM 2078 N N     . SER A 1 280 ? 135.807 113.617 125.056 1.00 31.44  ? 336 SER A N     1 
ATOM 2079 C CA    . SER A 1 280 ? 135.733 113.238 126.459 1.00 31.44  ? 336 SER A CA    1 
ATOM 2080 C C     . SER A 1 280 ? 134.294 112.927 126.835 1.00 31.44  ? 336 SER A C     1 
ATOM 2081 O O     . SER A 1 280 ? 133.369 113.653 126.465 1.00 31.44  ? 336 SER A O     1 
ATOM 2082 C CB    . SER A 1 280 ? 136.275 114.354 127.346 1.00 31.44  ? 336 SER A CB    1 
ATOM 2083 O OG    . SER A 1 280 ? 137.585 114.721 126.956 1.00 31.44  ? 336 SER A OG    1 
ATOM 2084 N N     . GLY A 1 281 ? 134.107 111.841 127.577 1.00 32.23  ? 337 GLY A N     1 
ATOM 2085 C CA    . GLY A 1 281 ? 132.781 111.393 127.951 1.00 32.23  ? 337 GLY A CA    1 
ATOM 2086 C C     . GLY A 1 281 ? 132.201 112.124 129.141 1.00 32.23  ? 337 GLY A C     1 
ATOM 2087 O O     . GLY A 1 281 ? 131.490 111.530 129.954 1.00 32.23  ? 337 GLY A O     1 
ATOM 2088 N N     . ASP A 1 282 ? 132.578 113.400 129.291 1.00 32.16  ? 338 ASP A N     1 
ATOM 2089 C CA    . ASP A 1 282 ? 132.060 114.239 130.381 1.00 32.16  ? 338 ASP A CA    1 
ATOM 2090 C C     . ASP A 1 282 ? 131.399 115.518 129.776 1.00 32.16  ? 338 ASP A C     1 
ATOM 2091 O O     . ASP A 1 282 ? 131.939 116.611 129.953 1.00 32.16  ? 338 ASP A O     1 
ATOM 2092 C CB    . ASP A 1 282 ? 133.159 114.614 131.372 1.00 32.16  ? 338 ASP A CB    1 
ATOM 2093 C CG    . ASP A 1 282 ? 133.535 113.467 132.299 1.00 32.16  ? 338 ASP A CG    1 
ATOM 2094 O OD1   . ASP A 1 282 ? 133.509 113.669 133.530 1.00 32.16  ? 338 ASP A OD1   1 
ATOM 2095 O OD2   . ASP A 1 282 ? 133.856 112.367 131.804 1.00 32.16  ? 338 ASP A OD2   1 
ATOM 2096 N N     . PRO A 1 283 ? 130.236 115.398 129.060 1.00 29.94  ? 339 PRO A N     1 
ATOM 2097 C CA    . PRO A 1 283 ? 129.626 116.566 128.417 1.00 29.94  ? 339 PRO A CA    1 
ATOM 2098 C C     . PRO A 1 283 ? 129.074 117.555 129.429 1.00 29.94  ? 339 PRO A C     1 
ATOM 2099 O O     . PRO A 1 283 ? 128.732 117.203 130.561 1.00 29.94  ? 339 PRO A O     1 
ATOM 2100 C CB    . PRO A 1 283 ? 128.500 115.960 127.569 1.00 29.94  ? 339 PRO A CB    1 
ATOM 2101 C CG    . PRO A 1 283 ? 128.832 114.513 127.448 1.00 29.94  ? 339 PRO A CG    1 
ATOM 2102 C CD    . PRO A 1 283 ? 129.514 114.161 128.728 1.00 29.94  ? 339 PRO A CD    1 
ATOM 2103 N N     . VAL A 1 284 ? 128.989 118.812 129.000 1.00 26.59  ? 340 VAL A N     1 
ATOM 2104 C CA    . VAL A 1 284 ? 128.370 119.881 129.774 1.00 26.59  ? 340 VAL A CA    1 
ATOM 2105 C C     . VAL A 1 284 ? 127.087 120.282 129.060 1.00 26.59  ? 340 VAL A C     1 
ATOM 2106 O O     . VAL A 1 284 ? 127.131 120.845 127.960 1.00 26.59  ? 340 VAL A O     1 
ATOM 2107 C CB    . VAL A 1 284 ? 129.314 121.082 129.935 1.00 26.59  ? 340 VAL A CB    1 
ATOM 2108 C CG1   . VAL A 1 284 ? 128.696 122.127 130.846 1.00 26.59  ? 340 VAL A CG1   1 
ATOM 2109 C CG2   . VAL A 1 284 ? 130.661 120.633 130.472 1.00 26.59  ? 340 VAL A CG2   1 
ATOM 2110 N N     . LEU A 1 285 ? 125.950 120.003 129.681 1.00 25.86  ? 341 LEU A N     1 
ATOM 2111 C CA    . LEU A 1 285 ? 124.651 120.284 129.090 1.00 25.86  ? 341 LEU A CA    1 
ATOM 2112 C C     . LEU A 1 285 ? 124.136 121.622 129.600 1.00 25.86  ? 341 LEU A C     1 
ATOM 2113 O O     . LEU A 1 285 ? 124.168 121.887 130.806 1.00 25.86  ? 341 LEU A O     1 
ATOM 2114 C CB    . LEU A 1 285 ? 123.647 119.179 129.415 1.00 25.86  ? 341 LEU A CB    1 
ATOM 2115 C CG    . LEU A 1 285 ? 124.105 117.732 129.251 1.00 25.86  ? 341 LEU A CG    1 
ATOM 2116 C CD1   . LEU A 1 285 ? 122.970 116.771 129.560 1.00 25.86  ? 341 LEU A CD1   1 
ATOM 2117 C CD2   . LEU A 1 285 ? 124.645 117.495 127.856 1.00 25.86  ? 341 LEU A CD2   1 
ATOM 2118 N N     . ASP A 1 286 ? 123.664 122.462 128.679 1.00 29.47  ? 342 ASP A N     1 
ATOM 2119 C CA    . ASP A 1 286 ? 123.093 123.760 129.026 1.00 29.47  ? 342 ASP A CA    1 
ATOM 2120 C C     . ASP A 1 286 ? 121.602 123.734 128.723 1.00 29.47  ? 342 ASP A C     1 
ATOM 2121 O O     . ASP A 1 286 ? 121.206 123.854 127.553 1.00 29.47  ? 342 ASP A O     1 
ATOM 2122 C CB    . ASP A 1 286 ? 123.785 124.883 128.250 1.00 29.47  ? 342 ASP A CB    1 
ATOM 2123 C CG    . ASP A 1 286 ? 123.522 126.248 128.847 1.00 29.47  ? 342 ASP A CG    1 
ATOM 2124 O OD1   . ASP A 1 286 ? 122.814 126.325 129.872 1.00 29.47  ? 342 ASP A OD1   1 
ATOM 2125 O OD2   . ASP A 1 286 ? 124.025 127.248 128.291 1.00 29.47  ? 342 ASP A OD2   1 
ATOM 2126 N N     . PRO A 1 287 ? 120.741 123.582 129.731 1.00 30.10  ? 343 PRO A N     1 
ATOM 2127 C CA    . PRO A 1 287 ? 119.314 123.343 129.457 1.00 30.10  ? 343 PRO A CA    1 
ATOM 2128 C C     . PRO A 1 287 ? 118.626 124.457 128.695 1.00 30.10  ? 343 PRO A C     1 
ATOM 2129 O O     . PRO A 1 287 ? 117.702 124.180 127.921 1.00 30.10  ? 343 PRO A O     1 
ATOM 2130 C CB    . PRO A 1 287 ? 118.715 123.179 130.861 1.00 30.10  ? 343 PRO A CB    1 
ATOM 2131 C CG    . PRO A 1 287 ? 119.873 122.808 131.732 1.00 30.10  ? 343 PRO A CG    1 
ATOM 2132 C CD    . PRO A 1 287 ? 121.038 123.556 131.171 1.00 30.10  ? 343 PRO A CD    1 
ATOM 2133 N N     . LYS A 1 288 ? 119.035 125.709 128.898 1.00 31.94  ? 344 LYS A N     1 
ATOM 2134 C CA    . LYS A 1 288 ? 118.315 126.825 128.295 1.00 31.94  ? 344 LYS A CA    1 
ATOM 2135 C C     . LYS A 1 288 ? 118.383 126.782 126.774 1.00 31.94  ? 344 LYS A C     1 
ATOM 2136 O O     . LYS A 1 288 ? 117.378 127.027 126.097 1.00 31.94  ? 344 LYS A O     1 
ATOM 2137 C CB    . LYS A 1 288 ? 118.870 128.151 128.815 1.00 31.94  ? 344 LYS A CB    1 
ATOM 2138 C CG    . LYS A 1 288 ? 119.387 128.097 130.244 1.00 31.94  ? 344 LYS A CG    1 
ATOM 2139 C CD    . LYS A 1 288 ? 119.924 129.449 130.689 1.00 31.94  ? 344 LYS A CD    1 
ATOM 2140 C CE    . LYS A 1 288 ? 121.141 129.868 129.879 1.00 31.94  ? 344 LYS A CE    1 
ATOM 2141 N NZ    . LYS A 1 288 ? 122.317 128.990 130.128 1.00 31.94  ? 344 LYS A NZ    1 
ATOM 2142 N N     . ARG A 1 289 ? 119.551 126.470 126.219 1.00 30.06  ? 345 ARG A N     1 
ATOM 2143 C CA    . ARG A 1 289 ? 119.747 126.575 124.781 1.00 30.06  ? 345 ARG A CA    1 
ATOM 2144 C C     . ARG A 1 289 ? 119.396 125.301 124.025 1.00 30.06  ? 345 ARG A C     1 
ATOM 2145 O O     . ARG A 1 289 ? 119.442 125.309 122.791 1.00 30.06  ? 345 ARG A O     1 
ATOM 2146 C CB    . ARG A 1 289 ? 121.198 126.957 124.476 1.00 30.06  ? 345 ARG A CB    1 
ATOM 2147 C CG    . ARG A 1 289 ? 121.639 128.267 125.098 1.00 30.06  ? 345 ARG A CG    1 
ATOM 2148 C CD    . ARG A 1 289 ? 123.019 128.659 124.617 1.00 30.06  ? 345 ARG A CD    1 
ATOM 2149 N NE    . ARG A 1 289 ? 123.576 129.750 125.405 1.00 30.06  ? 345 ARG A NE    1 
ATOM 2150 C CZ    . ARG A 1 289 ? 123.355 131.034 125.171 1.00 30.06  ? 345 ARG A CZ    1 
ATOM 2151 N NH1   . ARG A 1 289 ? 122.589 131.432 124.167 1.00 30.06  ? 345 ARG A NH1   1 
ATOM 2152 N NH2   . ARG A 1 289 ? 123.912 131.944 125.964 1.00 30.06  ? 345 ARG A NH2   1 
ATOM 2153 N N     . GLY A 1 290 ? 119.042 124.223 124.714 1.00 27.88  ? 346 GLY A N     1 
ATOM 2154 C CA    . GLY A 1 290 ? 118.828 122.961 124.027 1.00 27.88  ? 346 GLY A CA    1 
ATOM 2155 C C     . GLY A 1 290 ? 120.085 122.456 123.356 1.00 27.88  ? 346 GLY A C     1 
ATOM 2156 O O     . GLY A 1 290 ? 120.031 121.990 122.211 1.00 27.88  ? 346 GLY A O     1 
ATOM 2157 N N     . ILE A 1 291 ? 121.219 122.537 124.047 1.00 26.10  ? 347 ILE A N     1 
ATOM 2158 C CA    . ILE A 1 291 ? 122.531 122.291 123.474 1.00 26.10  ? 347 ILE A CA    1 
ATOM 2159 C C     . ILE A 1 291 ? 123.292 121.328 124.375 1.00 26.10  ? 347 ILE A C     1 
ATOM 2160 O O     . ILE A 1 291 ? 122.995 121.177 125.561 1.00 26.10  ? 347 ILE A O     1 
ATOM 2161 C CB    . ILE A 1 291 ? 123.323 123.608 123.300 1.00 26.10  ? 347 ILE A CB    1 
ATOM 2162 C CG1   . ILE A 1 291 ? 124.566 123.417 122.437 1.00 26.10  ? 347 ILE A CG1   1 
ATOM 2163 C CG2   . ILE A 1 291 ? 123.701 124.186 124.653 1.00 26.10  ? 347 ILE A CG2   1 
ATOM 2164 C CD1   . ILE A 1 291 ? 125.264 124.700 122.130 1.00 26.10  ? 347 ILE A CD1   1 
ATOM 2165 N N     . ALA A 1 292 ? 124.281 120.669 123.789 1.00 24.76  ? 348 ALA A N     1 
ATOM 2166 C CA    . ALA A 1 292 ? 125.252 119.879 124.524 1.00 24.76  ? 348 ALA A CA    1 
ATOM 2167 C C     . ALA A 1 292 ? 126.647 120.282 124.082 1.00 24.76  ? 348 ALA A C     1 
ATOM 2168 O O     . ALA A 1 292 ? 126.863 120.647 122.924 1.00 24.76  ? 348 ALA A O     1 
ATOM 2169 C CB    . ALA A 1 292 ? 125.043 118.396 124.296 1.00 24.76  ? 348 ALA A CB    1 
ATOM 2170 N N     . THR A 1 293 ? 127.593 120.222 125.009 1.00 26.25  ? 349 THR A N     1 
ATOM 2171 C CA    . THR A 1 293 ? 128.966 120.620 124.742 1.00 26.25  ? 349 THR A CA    1 
ATOM 2172 C C     . THR A 1 293 ? 129.893 119.446 125.015 1.00 26.25  ? 349 THR A C     1 
ATOM 2173 O O     . THR A 1 293 ? 129.758 118.770 126.039 1.00 26.25  ? 349 THR A O     1 
ATOM 2174 C CB    . THR A 1 293 ? 129.365 121.825 125.594 1.00 26.25  ? 349 THR A CB    1 
ATOM 2175 O OG1   . THR A 1 293 ? 128.418 122.882 125.397 1.00 26.25  ? 349 THR A OG1   1 
ATOM 2176 C CG2   . THR A 1 293 ? 130.748 122.322 125.196 1.00 26.25  ? 349 THR A CG2   1 
ATOM 2177 N N     . PHE A 1 294 ? 130.830 119.207 124.099 1.00 26.47  ? 350 PHE A N     1 
ATOM 2178 C CA    . PHE A 1 294 ? 131.762 118.096 124.195 1.00 26.47  ? 350 PHE A CA    1 
ATOM 2179 C C     . PHE A 1 294 ? 133.189 118.608 124.124 1.00 26.47  ? 350 PHE A C     1 
ATOM 2180 O O     . PHE A 1 294 ? 133.489 119.559 123.399 1.00 26.47  ? 350 PHE A O     1 
ATOM 2181 C CB    . PHE A 1 294 ? 131.545 117.080 123.077 1.00 26.47  ? 350 PHE A CB    1 
ATOM 2182 C CG    . PHE A 1 294 ? 130.394 116.159 123.310 1.00 26.47  ? 350 PHE A CG    1 
ATOM 2183 C CD1   . PHE A 1 294 ? 129.117 116.648 123.421 1.00 26.47  ? 350 PHE A CD1   1 
ATOM 2184 C CD2   . PHE A 1 294 ? 130.593 114.797 123.405 1.00 26.47  ? 350 PHE A CD2   1 
ATOM 2185 C CE1   . PHE A 1 294 ? 128.066 115.805 123.630 1.00 26.47  ? 350 PHE A CE1   1 
ATOM 2186 C CE2   . PHE A 1 294 ? 129.547 113.955 123.612 1.00 26.47  ? 350 PHE A CE2   1 
ATOM 2187 C CZ    . PHE A 1 294 ? 128.281 114.456 123.727 1.00 26.47  ? 350 PHE A CZ    1 
ATOM 2188 N N     . THR A 1 295 ? 134.061 117.970 124.884 1.00 30.49  ? 351 THR A N     1 
ATOM 2189 C CA    . THR A 1 295 ? 135.481 118.258 124.866 1.00 30.49  ? 351 THR A CA    1 
ATOM 2190 C C     . THR A 1 295 ? 136.159 117.243 123.940 1.00 30.49  ? 351 THR A C     1 
ATOM 2191 O O     . THR A 1 295 ? 135.534 116.285 123.480 1.00 30.49  ? 351 THR A O     1 
ATOM 2192 C CB    . THR A 1 295 ? 136.013 118.228 126.306 1.00 30.49  ? 351 THR A CB    1 
ATOM 2193 O OG1   . THR A 1 295 ? 135.203 119.084 127.121 1.00 30.49  ? 351 THR A OG1   1 
ATOM 2194 C CG2   . THR A 1 295 ? 137.447 118.739 126.385 1.00 30.49  ? 351 THR A CG2   1 
ATOM 2195 N N     . PHE A 1 296 ? 137.439 117.452 123.644 1.00 28.77  ? 352 PHE A N     1 
ATOM 2196 C CA    . PHE A 1 296 ? 138.246 116.497 122.901 1.00 28.77  ? 352 PHE A CA    1 
ATOM 2197 C C     . PHE A 1 296 ? 139.194 115.773 123.841 1.00 28.77  ? 352 PHE A C     1 
ATOM 2198 O O     . PHE A 1 296 ? 139.099 115.882 125.066 1.00 28.77  ? 352 PHE A O     1 
ATOM 2199 C CB    . PHE A 1 296 ? 139.081 117.157 121.789 1.00 28.77  ? 352 PHE A CB    1 
ATOM 2200 C CG    . PHE A 1 296 ? 138.300 117.530 120.562 1.00 28.77  ? 352 PHE A CG    1 
ATOM 2201 C CD1   . PHE A 1 296 ? 137.023 117.057 120.357 1.00 28.77  ? 352 PHE A CD1   1 
ATOM 2202 C CD2   . PHE A 1 296 ? 138.871 118.328 119.590 1.00 28.77  ? 352 PHE A CD2   1 
ATOM 2203 C CE1   . PHE A 1 296 ? 136.329 117.388 119.220 1.00 28.77  ? 352 PHE A CE1   1 
ATOM 2204 C CE2   . PHE A 1 296 ? 138.175 118.660 118.457 1.00 28.77  ? 352 PHE A CE2   1 
ATOM 2205 C CZ    . PHE A 1 296 ? 136.903 118.188 118.274 1.00 28.77  ? 352 PHE A CZ    1 
ATOM 2206 N N     . LYS A 1 297 ? 140.095 115.001 123.234 1.00 29.57  ? 353 LYS A N     1 
ATOM 2207 C CA    . LYS A 1 297 ? 141.243 114.452 123.934 1.00 29.57  ? 353 LYS A CA    1 
ATOM 2208 C C     . LYS A 1 297 ? 142.308 115.528 124.119 1.00 29.57  ? 353 LYS A C     1 
ATOM 2209 O O     . LYS A 1 297 ? 142.106 116.707 123.824 1.00 29.57  ? 353 LYS A O     1 
ATOM 2210 C CB    . LYS A 1 297 ? 141.844 113.279 123.163 1.00 29.57  ? 353 LYS A CB    1 
ATOM 2211 C CG    . LYS A 1 297 ? 140.904 112.112 122.910 1.00 29.57  ? 353 LYS A CG    1 
ATOM 2212 C CD    . LYS A 1 297 ? 140.629 111.308 124.170 1.00 29.57  ? 353 LYS A CD    1 
ATOM 2213 C CE    . LYS A 1 297 ? 139.260 111.619 124.740 1.00 29.57  ? 353 LYS A CE    1 
ATOM 2214 N NZ    . LYS A 1 297 ? 138.921 110.709 125.863 1.00 29.57  ? 353 LYS A NZ    1 
ATOM 2215 N N     . LEU A 1 298 ? 143.464 115.100 124.617 1.00 29.92  ? 354 LEU A N     1 
ATOM 2216 C CA    . LEU A 1 298 ? 144.595 115.998 124.835 1.00 29.92  ? 354 LEU A CA    1 
ATOM 2217 C C     . LEU A 1 298 ? 145.420 116.062 123.551 1.00 29.92  ? 354 LEU A C     1 
ATOM 2218 O O     . LEU A 1 298 ? 146.510 115.496 123.439 1.00 29.92  ? 354 LEU A O     1 
ATOM 2219 C CB    . LEU A 1 298 ? 145.424 115.523 126.020 1.00 29.92  ? 354 LEU A CB    1 
ATOM 2220 C CG    . LEU A 1 298 ? 144.646 115.348 127.327 1.00 29.92  ? 354 LEU A CG    1 
ATOM 2221 C CD1   . LEU A 1 298 ? 145.520 114.704 128.393 1.00 29.92  ? 354 LEU A CD1   1 
ATOM 2222 C CD2   . LEU A 1 298 ? 144.099 116.679 127.813 1.00 29.92  ? 354 LEU A CD2   1 
ATOM 2223 N N     . GLY A 1 299 ? 144.881 116.764 122.561 1.00 31.79  ? 355 GLY A N     1 
ATOM 2224 C CA    . GLY A 1 299 ? 145.584 116.957 121.304 1.00 31.79  ? 355 GLY A CA    1 
ATOM 2225 C C     . GLY A 1 299 ? 144.825 116.497 120.075 1.00 31.79  ? 355 GLY A C     1 
ATOM 2226 O O     . GLY A 1 299 ? 145.066 116.980 118.969 1.00 31.79  ? 355 GLY A O     1 
ATOM 2227 P P     . DC  B 2 13  ? 113.006 175.213 126.474 1.00 196.37 ? -20 DC  C P     1 
ATOM 2228 O OP1   . DC  B 2 13  ? 113.529 173.829 126.495 1.00 196.37 ? -20 DC  C OP1   1 
ATOM 2229 O OP2   . DC  B 2 13  ? 113.018 175.989 125.214 1.00 196.37 ? -20 DC  C OP2   1 
ATOM 2230 O "O5'" . DC  B 2 13  ? 113.755 176.076 127.596 1.00 196.37 ? -20 DC  C "O5'" 1 
ATOM 2231 C "C5'" . DC  B 2 13  ? 114.847 176.919 127.239 1.00 196.37 ? -20 DC  C "C5'" 1 
ATOM 2232 C "C4'" . DC  B 2 13  ? 116.142 176.428 127.865 1.00 196.37 ? -20 DC  C "C4'" 1 
ATOM 2233 O "O4'" . DC  B 2 13  ? 116.144 176.735 129.286 1.00 196.37 ? -20 DC  C "O4'" 1 
ATOM 2234 C "C3'" . DC  B 2 13  ? 116.388 174.921 127.749 1.00 196.37 ? -20 DC  C "C3'" 1 
ATOM 2235 O "O3'" . DC  B 2 13  ? 117.739 174.670 127.380 1.00 196.37 ? -20 DC  C "O3'" 1 
ATOM 2236 C "C2'" . DC  B 2 13  ? 116.083 174.400 129.152 1.00 196.37 ? -20 DC  C "C2'" 1 
ATOM 2237 C "C1'" . DC  B 2 13  ? 116.499 175.582 130.014 1.00 196.37 ? -20 DC  C "C1'" 1 
ATOM 2238 N N1    . DC  B 2 13  ? 115.827 175.621 131.356 1.00 196.37 ? -20 DC  C N1    1 
ATOM 2239 C C2    . DC  B 2 13  ? 114.450 175.882 131.454 1.00 196.37 ? -20 DC  C C2    1 
ATOM 2240 O O2    . DC  B 2 13  ? 113.792 176.082 130.425 1.00 196.37 ? -20 DC  C O2    1 
ATOM 2241 N N3    . DC  B 2 13  ? 113.875 175.908 132.682 1.00 196.37 ? -20 DC  C N3    1 
ATOM 2242 C C4    . DC  B 2 13  ? 114.611 175.687 133.771 1.00 196.37 ? -20 DC  C C4    1 
ATOM 2243 N N4    . DC  B 2 13  ? 113.998 175.724 134.959 1.00 196.37 ? -20 DC  C N4    1 
ATOM 2244 C C5    . DC  B 2 13  ? 116.009 175.421 133.693 1.00 196.37 ? -20 DC  C C5    1 
ATOM 2245 C C6    . DC  B 2 13  ? 116.568 175.397 132.479 1.00 196.37 ? -20 DC  C C6    1 
ATOM 2246 P P     . DT  B 2 14  ? 118.089 173.460 126.381 1.00 191.92 ? -19 DT  C P     1 
ATOM 2247 O OP1   . DT  B 2 14  ? 118.021 173.985 125.000 1.00 191.92 ? -19 DT  C OP1   1 
ATOM 2248 O OP2   . DT  B 2 14  ? 117.253 172.302 126.770 1.00 191.92 ? -19 DT  C OP2   1 
ATOM 2249 O "O5'" . DT  B 2 14  ? 119.610 173.100 126.722 1.00 191.92 ? -19 DT  C "O5'" 1 
ATOM 2250 C "C5'" . DT  B 2 14  ? 119.967 172.673 128.032 1.00 191.92 ? -19 DT  C "C5'" 1 
ATOM 2251 C "C4'" . DT  B 2 14  ? 120.554 173.821 128.831 1.00 191.92 ? -19 DT  C "C4'" 1 
ATOM 2252 O "O4'" . DT  B 2 14  ? 119.564 174.317 129.765 1.00 191.92 ? -19 DT  C "O4'" 1 
ATOM 2253 C "C3'" . DT  B 2 14  ? 121.746 173.459 129.697 1.00 191.92 ? -19 DT  C "C3'" 1 
ATOM 2254 O "O3'" . DT  B 2 14  ? 122.941 173.497 128.928 1.00 191.92 ? -19 DT  C "O3'" 1 
ATOM 2255 C "C2'" . DT  B 2 14  ? 121.711 174.568 130.741 1.00 191.92 ? -19 DT  C "C2'" 1 
ATOM 2256 C "C1'" . DT  B 2 14  ? 120.205 174.749 130.954 1.00 191.92 ? -19 DT  C "C1'" 1 
ATOM 2257 N N1    . DT  B 2 14  ? 119.674 173.957 132.100 1.00 191.92 ? -19 DT  C N1    1 
ATOM 2258 C C2    . DT  B 2 14  ? 119.725 174.493 133.364 1.00 191.92 ? -19 DT  C C2    1 
ATOM 2259 O O2    . DT  B 2 14  ? 120.179 175.598 133.602 1.00 191.92 ? -19 DT  C O2    1 
ATOM 2260 N N3    . DT  B 2 14  ? 119.222 173.685 134.348 1.00 191.92 ? -19 DT  C N3    1 
ATOM 2261 C C4    . DT  B 2 14  ? 118.686 172.420 134.197 1.00 191.92 ? -19 DT  C C4    1 
ATOM 2262 O O4    . DT  B 2 14  ? 118.256 171.773 135.147 1.00 191.92 ? -19 DT  C O4    1 
ATOM 2263 C C5    . DT  B 2 14  ? 118.664 171.915 132.845 1.00 191.92 ? -19 DT  C C5    1 
ATOM 2264 C C7    . DT  B 2 14  ? 118.104 170.554 132.556 1.00 191.92 ? -19 DT  C C7    1 
ATOM 2265 C C6    . DT  B 2 14  ? 119.152 172.699 131.874 1.00 191.92 ? -19 DT  C C6    1 
ATOM 2266 P P     . DT  B 2 15  ? 123.634 172.129 128.447 1.00 188.76 ? -18 DT  C P     1 
ATOM 2267 O OP1   . DT  B 2 15  ? 125.087 172.379 128.318 1.00 188.76 ? -18 DT  C OP1   1 
ATOM 2268 O OP2   . DT  B 2 15  ? 122.884 171.643 127.269 1.00 188.76 ? -18 DT  C OP2   1 
ATOM 2269 O "O5'" . DT  B 2 15  ? 123.376 171.120 129.667 1.00 188.76 ? -18 DT  C "O5'" 1 
ATOM 2270 C "C5'" . DT  B 2 15  ? 124.473 170.532 130.368 1.00 188.76 ? -18 DT  C "C5'" 1 
ATOM 2271 C "C4'" . DT  B 2 15  ? 125.116 171.535 131.310 1.00 188.76 ? -18 DT  C "C4'" 1 
ATOM 2272 O "O4'" . DT  B 2 15  ? 124.098 172.189 132.086 1.00 188.76 ? -18 DT  C "O4'" 1 
ATOM 2273 C "C3'" . DT  B 2 15  ? 126.042 170.943 132.349 1.00 188.76 ? -18 DT  C "C3'" 1 
ATOM 2274 O "O3'" . DT  B 2 15  ? 127.333 170.732 131.788 1.00 188.76 ? -18 DT  C "O3'" 1 
ATOM 2275 C "C2'" . DT  B 2 15  ? 126.063 172.038 133.420 1.00 188.76 ? -18 DT  C "C2'" 1 
ATOM 2276 C "C1'" . DT  B 2 15  ? 124.677 172.691 133.277 1.00 188.76 ? -18 DT  C "C1'" 1 
ATOM 2277 N N1    . DT  B 2 15  ? 123.758 172.426 134.450 1.00 188.76 ? -18 DT  C N1    1 
ATOM 2278 C C2    . DT  B 2 15  ? 122.392 172.311 134.260 1.00 188.76 ? -18 DT  C C2    1 
ATOM 2279 O O2    . DT  B 2 15  ? 121.849 172.403 133.177 1.00 188.76 ? -18 DT  C O2    1 
ATOM 2280 N N3    . DT  B 2 15  ? 121.674 172.079 135.403 1.00 188.76 ? -18 DT  C N3    1 
ATOM 2281 C C4    . DT  B 2 15  ? 122.164 171.954 136.689 1.00 188.76 ? -18 DT  C C4    1 
ATOM 2282 O O4    . DT  B 2 15  ? 121.432 171.745 137.652 1.00 188.76 ? -18 DT  C O4    1 
ATOM 2283 C C5    . DT  B 2 15  ? 123.594 172.088 136.820 1.00 188.76 ? -18 DT  C C5    1 
ATOM 2284 C C7    . DT  B 2 15  ? 124.244 171.973 138.166 1.00 188.76 ? -18 DT  C C7    1 
ATOM 2285 C C6    . DT  B 2 15  ? 124.311 172.317 135.710 1.00 188.76 ? -18 DT  C C6    1 
ATOM 2286 P P     . DC  B 2 16  ? 128.204 169.456 132.232 1.00 185.09 ? -17 DC  C P     1 
ATOM 2287 O OP1   . DC  B 2 16  ? 129.545 169.593 131.622 1.00 185.09 ? -17 DC  C OP1   1 
ATOM 2288 O OP2   . DC  B 2 16  ? 127.397 168.244 131.972 1.00 185.09 ? -17 DC  C OP2   1 
ATOM 2289 O "O5'" . DC  B 2 16  ? 128.338 169.625 133.816 1.00 185.09 ? -17 DC  C "O5'" 1 
ATOM 2290 C "C5'" . DC  B 2 16  ? 128.389 168.481 134.655 1.00 185.09 ? -17 DC  C "C5'" 1 
ATOM 2291 C "C4'" . DC  B 2 16  ? 127.936 168.834 136.059 1.00 185.09 ? -17 DC  C "C4'" 1 
ATOM 2292 O "O4'" . DC  B 2 16  ? 126.594 169.393 136.008 1.00 185.09 ? -17 DC  C "O4'" 1 
ATOM 2293 C "C3'" . DC  B 2 16  ? 127.859 167.660 137.031 1.00 185.09 ? -17 DC  C "C3'" 1 
ATOM 2294 O "O3'" . DC  B 2 16  ? 128.190 168.102 138.341 1.00 185.09 ? -17 DC  C "O3'" 1 
ATOM 2295 C "C2'" . DC  B 2 16  ? 126.393 167.253 136.936 1.00 185.09 ? -17 DC  C "C2'" 1 
ATOM 2296 C "C1'" . DC  B 2 16  ? 125.726 168.613 136.802 1.00 185.09 ? -17 DC  C "C1'" 1 
ATOM 2297 N N1    . DC  B 2 16  ? 124.388 168.567 136.144 1.00 185.09 ? -17 DC  C N1    1 
ATOM 2298 C C2    . DC  B 2 16  ? 123.249 168.316 136.915 1.00 185.09 ? -17 DC  C C2    1 
ATOM 2299 O O2    . DC  B 2 16  ? 123.376 168.133 138.131 1.00 185.09 ? -17 DC  C O2    1 
ATOM 2300 N N3    . DC  B 2 16  ? 122.039 168.281 136.307 1.00 185.09 ? -17 DC  C N3    1 
ATOM 2301 C C4    . DC  B 2 16  ? 121.946 168.484 134.993 1.00 185.09 ? -17 DC  C C4    1 
ATOM 2302 N N4    . DC  B 2 16  ? 120.731 168.438 134.437 1.00 185.09 ? -17 DC  C N4    1 
ATOM 2303 C C5    . DC  B 2 16  ? 123.095 168.742 134.189 1.00 185.09 ? -17 DC  C C5    1 
ATOM 2304 C C6    . DC  B 2 16  ? 124.284 168.775 134.801 1.00 185.09 ? -17 DC  C C6    1 
ATOM 2305 P P     . DA  B 2 17  ? 129.088 167.183 139.306 1.00 175.14 ? -16 DA  C P     1 
ATOM 2306 O OP1   . DA  B 2 17  ? 129.640 168.052 140.369 1.00 175.14 ? -16 DA  C OP1   1 
ATOM 2307 O OP2   . DA  B 2 17  ? 130.005 166.396 138.451 1.00 175.14 ? -16 DA  C OP2   1 
ATOM 2308 O "O5'" . DA  B 2 17  ? 128.038 166.170 139.960 1.00 175.14 ? -16 DA  C "O5'" 1 
ATOM 2309 C "C5'" . DA  B 2 17  ? 126.827 166.664 140.527 1.00 175.14 ? -16 DA  C "C5'" 1 
ATOM 2310 C "C4'" . DA  B 2 17  ? 126.073 165.549 141.227 1.00 175.14 ? -16 DA  C "C4'" 1 
ATOM 2311 O "O4'" . DA  B 2 17  ? 124.664 165.610 140.867 1.00 175.14 ? -16 DA  C "O4'" 1 
ATOM 2312 C "C3'" . DA  B 2 17  ? 126.540 164.136 140.866 1.00 175.14 ? -16 DA  C "C3'" 1 
ATOM 2313 O "O3'" . DA  B 2 17  ? 126.577 163.321 142.033 1.00 175.14 ? -16 DA  C "O3'" 1 
ATOM 2314 C "C2'" . DA  B 2 17  ? 125.471 163.664 139.888 1.00 175.14 ? -16 DA  C "C2'" 1 
ATOM 2315 C "C1'" . DA  B 2 17  ? 124.237 164.327 140.473 1.00 175.14 ? -16 DA  C "C1'" 1 
ATOM 2316 N N9    . DA  B 2 17  ? 123.131 164.458 139.526 1.00 175.14 ? -16 DA  C N9    1 
ATOM 2317 C C8    . DA  B 2 17  ? 123.115 165.182 138.367 1.00 175.14 ? -16 DA  C C8    1 
ATOM 2318 N N7    . DA  B 2 17  ? 121.978 165.112 137.714 1.00 175.14 ? -16 DA  C N7    1 
ATOM 2319 C C5    . DA  B 2 17  ? 121.196 164.280 138.497 1.00 175.14 ? -16 DA  C C5    1 
ATOM 2320 C C6    . DA  B 2 17  ? 119.876 163.805 138.357 1.00 175.14 ? -16 DA  C C6    1 
ATOM 2321 N N6    . DA  B 2 17  ? 119.086 164.119 137.327 1.00 175.14 ? -16 DA  C N6    1 
ATOM 2322 N N1    . DA  B 2 17  ? 119.399 162.992 139.319 1.00 175.14 ? -16 DA  C N1    1 
ATOM 2323 C C2    . DA  B 2 17  ? 120.191 162.678 140.350 1.00 175.14 ? -16 DA  C C2    1 
ATOM 2324 N N3    . DA  B 2 17  ? 121.445 163.060 140.591 1.00 175.14 ? -16 DA  C N3    1 
ATOM 2325 C C4    . DA  B 2 17  ? 121.892 163.868 139.617 1.00 175.14 ? -16 DA  C C4    1 
ATOM 2326 P P     . DG  B 2 18  ? 127.524 162.023 142.084 1.00 168.02 ? -15 DG  C P     1 
ATOM 2327 O OP1   . DG  B 2 18  ? 128.415 162.164 143.256 1.00 168.02 ? -15 DG  C OP1   1 
ATOM 2328 O OP2   . DG  B 2 18  ? 128.106 161.837 140.736 1.00 168.02 ? -15 DG  C OP2   1 
ATOM 2329 O "O5'" . DG  B 2 18  ? 126.509 160.814 142.350 1.00 168.02 ? -15 DG  C "O5'" 1 
ATOM 2330 C "C5'" . DG  B 2 18  ? 125.831 160.713 143.599 1.00 168.02 ? -15 DG  C "C5'" 1 
ATOM 2331 C "C4'" . DG  B 2 18  ? 124.673 159.732 143.512 1.00 168.02 ? -15 DG  C "C4'" 1 
ATOM 2332 O "O4'" . DG  B 2 18  ? 123.668 160.249 142.599 1.00 168.02 ? -15 DG  C "O4'" 1 
ATOM 2333 C "C3'" . DG  B 2 18  ? 125.042 158.339 142.998 1.00 168.02 ? -15 DG  C "C3'" 1 
ATOM 2334 O "O3'" . DG  B 2 18  ? 124.342 157.341 143.736 1.00 168.02 ? -15 DG  C "O3'" 1 
ATOM 2335 C "C2'" . DG  B 2 18  ? 124.589 158.376 141.543 1.00 168.02 ? -15 DG  C "C2'" 1 
ATOM 2336 C "C1'" . DG  B 2 18  ? 123.364 159.274 141.626 1.00 168.02 ? -15 DG  C "C1'" 1 
ATOM 2337 N N9    . DG  B 2 18  ? 123.061 159.952 140.370 1.00 168.02 ? -15 DG  C N9    1 
ATOM 2338 C C8    . DG  B 2 18  ? 123.886 160.795 139.669 1.00 168.02 ? -15 DG  C C8    1 
ATOM 2339 N N7    . DG  B 2 18  ? 123.351 161.255 138.573 1.00 168.02 ? -15 DG  C N7    1 
ATOM 2340 C C5    . DG  B 2 18  ? 122.089 160.676 138.543 1.00 168.02 ? -15 DG  C C5    1 
ATOM 2341 C C6    . DG  B 2 18  ? 121.053 160.805 137.592 1.00 168.02 ? -15 DG  C C6    1 
ATOM 2342 O O6    . DG  B 2 18  ? 121.045 161.476 136.552 1.00 168.02 ? -15 DG  C O6    1 
ATOM 2343 N N1    . DG  B 2 18  ? 119.938 160.050 137.942 1.00 168.02 ? -15 DG  C N1    1 
ATOM 2344 C C2    . DG  B 2 18  ? 119.838 159.272 139.069 1.00 168.02 ? -15 DG  C C2    1 
ATOM 2345 N N2    . DG  B 2 18  ? 118.682 158.615 139.238 1.00 168.02 ? -15 DG  C N2    1 
ATOM 2346 N N3    . DG  B 2 18  ? 120.803 159.143 139.970 1.00 168.02 ? -15 DG  C N3    1 
ATOM 2347 C C4    . DG  B 2 18  ? 121.894 159.873 139.644 1.00 168.02 ? -15 DG  C C4    1 
ATOM 2348 P P     . DC  B 2 19  ? 125.047 155.933 144.061 1.00 160.60 ? -14 DC  C P     1 
ATOM 2349 O OP1   . DC  B 2 19  ? 125.431 155.945 145.490 1.00 160.60 ? -14 DC  C OP1   1 
ATOM 2350 O OP2   . DC  B 2 19  ? 126.075 155.695 143.024 1.00 160.60 ? -14 DC  C OP2   1 
ATOM 2351 O "O5'" . DC  B 2 19  ? 123.880 154.858 143.850 1.00 160.60 ? -14 DC  C "O5'" 1 
ATOM 2352 C "C5'" . DC  B 2 19  ? 123.899 153.996 142.715 1.00 160.60 ? -14 DC  C "C5'" 1 
ATOM 2353 C "C4'" . DC  B 2 19  ? 122.492 153.556 142.351 1.00 160.60 ? -14 DC  C "C4'" 1 
ATOM 2354 O "O4'" . DC  B 2 19  ? 121.685 154.728 142.071 1.00 160.60 ? -14 DC  C "O4'" 1 
ATOM 2355 C "C3'" . DC  B 2 19  ? 122.390 152.692 141.103 1.00 160.60 ? -14 DC  C "C3'" 1 
ATOM 2356 O "O3'" . DC  B 2 19  ? 122.518 151.316 141.446 1.00 160.60 ? -14 DC  C "O3'" 1 
ATOM 2357 C "C2'" . DC  B 2 19  ? 120.987 153.010 140.605 1.00 160.60 ? -14 DC  C "C2'" 1 
ATOM 2358 C "C1'" . DC  B 2 19  ? 120.857 154.490 140.947 1.00 160.60 ? -14 DC  C "C1'" 1 
ATOM 2359 N N1    . DC  B 2 19  ? 121.271 155.409 139.838 1.00 160.60 ? -14 DC  C N1    1 
ATOM 2360 C C2    . DC  B 2 19  ? 120.403 155.636 138.764 1.00 160.60 ? -14 DC  C C2    1 
ATOM 2361 O O2    . DC  B 2 19  ? 119.306 155.063 138.743 1.00 160.60 ? -14 DC  C O2    1 
ATOM 2362 N N3    . DC  B 2 19  ? 120.791 156.475 137.772 1.00 160.60 ? -14 DC  C N3    1 
ATOM 2363 C C4    . DC  B 2 19  ? 121.982 157.073 137.830 1.00 160.60 ? -14 DC  C C4    1 
ATOM 2364 N N4    . DC  B 2 19  ? 122.321 157.893 136.830 1.00 160.60 ? -14 DC  C N4    1 
ATOM 2365 C C5    . DC  B 2 19  ? 122.879 156.856 138.916 1.00 160.60 ? -14 DC  C C5    1 
ATOM 2366 C C6    . DC  B 2 19  ? 122.486 156.029 139.890 1.00 160.60 ? -14 DC  C C6    1 
ATOM 2367 P P     . DA  B 2 20  ? 123.003 150.248 140.346 1.00 150.51 ? -13 DA  C P     1 
ATOM 2368 O OP1   . DA  B 2 20  ? 123.173 148.947 141.030 1.00 150.51 ? -13 DA  C OP1   1 
ATOM 2369 O OP2   . DA  B 2 20  ? 124.139 150.846 139.611 1.00 150.51 ? -13 DA  C OP2   1 
ATOM 2370 O "O5'" . DA  B 2 20  ? 121.767 150.141 139.334 1.00 150.51 ? -13 DA  C "O5'" 1 
ATOM 2371 C "C5'" . DA  B 2 20  ? 120.531 149.579 139.770 1.00 150.51 ? -13 DA  C "C5'" 1 
ATOM 2372 C "C4'" . DA  B 2 20  ? 119.439 149.812 138.740 1.00 150.51 ? -13 DA  C "C4'" 1 
ATOM 2373 O "O4'" . DA  B 2 20  ? 119.228 151.233 138.574 1.00 150.51 ? -13 DA  C "O4'" 1 
ATOM 2374 C "C3'" . DA  B 2 20  ? 119.750 149.292 137.347 1.00 150.51 ? -13 DA  C "C3'" 1 
ATOM 2375 O "O3'" . DA  B 2 20  ? 119.351 147.929 137.239 1.00 150.51 ? -13 DA  C "O3'" 1 
ATOM 2376 C "C2'" . DA  B 2 20  ? 118.889 150.194 136.466 1.00 150.51 ? -13 DA  C "C2'" 1 
ATOM 2377 C "C1'" . DA  B 2 20  ? 118.915 151.523 137.223 1.00 150.51 ? -13 DA  C "C1'" 1 
ATOM 2378 N N9    . DA  B 2 20  ? 119.898 152.476 136.711 1.00 150.51 ? -13 DA  C N9    1 
ATOM 2379 C C8    . DA  B 2 20  ? 121.104 152.797 137.268 1.00 150.51 ? -13 DA  C C8    1 
ATOM 2380 N N7    . DA  B 2 20  ? 121.780 153.693 136.591 1.00 150.51 ? -13 DA  C N7    1 
ATOM 2381 C C5    . DA  B 2 20  ? 120.963 153.980 135.511 1.00 150.51 ? -13 DA  C C5    1 
ATOM 2382 C C6    . DA  B 2 20  ? 121.108 154.855 134.417 1.00 150.51 ? -13 DA  C C6    1 
ATOM 2383 N N6    . DA  B 2 20  ? 122.180 155.632 134.233 1.00 150.51 ? -13 DA  C N6    1 
ATOM 2384 N N1    . DA  B 2 20  ? 120.105 154.900 133.517 1.00 150.51 ? -13 DA  C N1    1 
ATOM 2385 C C2    . DA  B 2 20  ? 119.033 154.121 133.705 1.00 150.51 ? -13 DA  C C2    1 
ATOM 2386 N N3    . DA  B 2 20  ? 118.784 153.261 134.691 1.00 150.51 ? -13 DA  C N3    1 
ATOM 2387 C C4    . DA  B 2 20  ? 119.798 153.238 135.569 1.00 150.51 ? -13 DA  C C4    1 
ATOM 2388 P P     . DG  B 2 21  ? 120.454 146.763 137.141 1.00 137.17 ? -12 DG  C P     1 
ATOM 2389 O OP1   . DG  B 2 21  ? 119.761 145.477 137.374 1.00 137.17 ? -12 DG  C OP1   1 
ATOM 2390 O OP2   . DG  B 2 21  ? 121.601 147.144 137.993 1.00 137.17 ? -12 DG  C OP2   1 
ATOM 2391 O "O5'" . DG  B 2 21  ? 120.941 146.815 135.619 1.00 137.17 ? -12 DG  C "O5'" 1 
ATOM 2392 C "C5'" . DG  B 2 21  ? 120.129 146.263 134.589 1.00 137.17 ? -12 DG  C "C5'" 1 
ATOM 2393 C "C4'" . DG  B 2 21  ? 119.268 147.334 133.945 1.00 137.17 ? -12 DG  C "C4'" 1 
ATOM 2394 O "O4'" . DG  B 2 21  ? 119.972 148.587 133.967 1.00 137.17 ? -12 DG  C "O4'" 1 
ATOM 2395 C "C3'" . DG  B 2 21  ? 118.927 147.080 132.478 1.00 137.17 ? -12 DG  C "C3'" 1 
ATOM 2396 O "O3'" . DG  B 2 21  ? 117.591 146.603 132.361 1.00 137.17 ? -12 DG  C "O3'" 1 
ATOM 2397 C "C2'" . DG  B 2 21  ? 119.105 148.447 131.788 1.00 137.17 ? -12 DG  C "C2'" 1 
ATOM 2398 C "C1'" . DG  B 2 21  ? 119.490 149.394 132.926 1.00 137.17 ? -12 DG  C "C1'" 1 
ATOM 2399 N N9    . DG  B 2 21  ? 120.542 150.346 132.570 1.00 137.17 ? -12 DG  C N9    1 
ATOM 2400 C C8    . DG  B 2 21  ? 121.705 150.583 133.263 1.00 137.17 ? -12 DG  C C8    1 
ATOM 2401 N N7    . DG  B 2 21  ? 122.465 151.488 132.712 1.00 137.17 ? -12 DG  C N7    1 
ATOM 2402 C C5    . DG  B 2 21  ? 121.765 151.878 131.579 1.00 137.17 ? -12 DG  C C5    1 
ATOM 2403 C C6    . DG  B 2 21  ? 122.095 152.832 130.588 1.00 137.17 ? -12 DG  C C6    1 
ATOM 2404 O O6    . DG  B 2 21  ? 123.102 153.546 130.513 1.00 137.17 ? -12 DG  C O6    1 
ATOM 2405 N N1    . DG  B 2 21  ? 121.111 152.922 129.609 1.00 137.17 ? -12 DG  C N1    1 
ATOM 2406 C C2    . DG  B 2 21  ? 119.953 152.183 129.589 1.00 137.17 ? -12 DG  C C2    1 
ATOM 2407 N N2    . DG  B 2 21  ? 119.121 152.415 128.566 1.00 137.17 ? -12 DG  C N2    1 
ATOM 2408 N N3    . DG  B 2 21  ? 119.627 151.288 130.513 1.00 137.17 ? -12 DG  C N3    1 
ATOM 2409 C C4    . DG  B 2 21  ? 120.578 151.186 131.474 1.00 137.17 ? -12 DG  C C4    1 
ATOM 2410 P P     . DC  B 2 22  ? 117.246 145.431 131.318 1.00 128.55 ? -11 DC  C P     1 
ATOM 2411 O OP1   . DC  B 2 22  ? 115.773 145.366 131.185 1.00 128.55 ? -11 DC  C OP1   1 
ATOM 2412 O OP2   . DC  B 2 22  ? 118.001 144.226 131.727 1.00 128.55 ? -11 DC  C OP2   1 
ATOM 2413 O "O5'" . DC  B 2 22  ? 117.838 145.968 129.934 1.00 128.55 ? -11 DC  C "O5'" 1 
ATOM 2414 C "C5'" . DC  B 2 22  ? 118.182 145.053 128.904 1.00 128.55 ? -11 DC  C "C5'" 1 
ATOM 2415 C "C4'" . DC  B 2 22  ? 117.180 145.116 127.768 1.00 128.55 ? -11 DC  C "C4'" 1 
ATOM 2416 O "O4'" . DC  B 2 22  ? 116.489 146.395 127.797 1.00 128.55 ? -11 DC  C "O4'" 1 
ATOM 2417 C "C3'" . DC  B 2 22  ? 117.787 145.040 126.379 1.00 128.55 ? -11 DC  C "C3'" 1 
ATOM 2418 O "O3'" . DC  B 2 22  ? 117.961 143.689 125.978 1.00 128.55 ? -11 DC  C "O3'" 1 
ATOM 2419 C "C2'" . DC  B 2 22  ? 116.730 145.745 125.546 1.00 128.55 ? -11 DC  C "C2'" 1 
ATOM 2420 C "C1'" . DC  B 2 22  ? 116.360 146.898 126.475 1.00 128.55 ? -11 DC  C "C1'" 1 
ATOM 2421 N N1    . DC  B 2 22  ? 117.256 148.090 126.329 1.00 128.55 ? -11 DC  C N1    1 
ATOM 2422 C C2    . DC  B 2 22  ? 117.232 148.842 125.145 1.00 128.55 ? -11 DC  C C2    1 
ATOM 2423 O O2    . DC  B 2 22  ? 116.464 148.514 124.232 1.00 128.55 ? -11 DC  C O2    1 
ATOM 2424 N N3    . DC  B 2 22  ? 118.054 149.914 125.034 1.00 128.55 ? -11 DC  C N3    1 
ATOM 2425 C C4    . DC  B 2 22  ? 118.868 150.240 126.037 1.00 128.55 ? -11 DC  C C4    1 
ATOM 2426 N N4    . DC  B 2 22  ? 119.659 151.305 125.879 1.00 128.55 ? -11 DC  C N4    1 
ATOM 2427 C C5    . DC  B 2 22  ? 118.907 149.489 127.248 1.00 128.55 ? -11 DC  C C5    1 
ATOM 2428 C C6    . DC  B 2 22  ? 118.093 148.434 127.349 1.00 128.55 ? -11 DC  C C6    1 
ATOM 2429 P P     . DA  B 2 23  ? 119.070 143.258 124.852 1.00 115.65 ? -10 DA  C P     1 
ATOM 2430 O OP1   . DA  B 2 23  ? 118.368 143.105 123.552 1.00 115.65 ? -10 DA  C OP1   1 
ATOM 2431 O OP2   . DA  B 2 23  ? 119.854 142.121 125.395 1.00 115.65 ? -10 DA  C OP2   1 
ATOM 2432 O "O5'" . DA  B 2 23  ? 120.064 144.502 124.726 1.00 115.65 ? -10 DA  C "O5'" 1 
ATOM 2433 C "C5'" . DA  B 2 23  ? 119.882 145.488 123.686 1.00 115.65 ? -10 DA  C "C5'" 1 
ATOM 2434 C "C4'" . DA  B 2 23  ? 121.145 146.290 123.476 1.00 115.65 ? -10 DA  C "C4'" 1 
ATOM 2435 O "O4'" . DA  B 2 23  ? 121.218 147.383 124.414 1.00 115.65 ? -10 DA  C "O4'" 1 
ATOM 2436 C "C3'" . DA  B 2 23  ? 122.446 145.526 123.686 1.00 115.65 ? -10 DA  C "C3'" 1 
ATOM 2437 O "O3'" . DA  B 2 23  ? 122.820 144.831 122.487 1.00 115.65 ? -10 DA  C "O3'" 1 
ATOM 2438 C "C2'" . DA  B 2 23  ? 123.435 146.633 124.015 1.00 115.65 ? -10 DA  C "C2'" 1 
ATOM 2439 C "C1'" . DA  B 2 23  ? 122.572 147.812 124.467 1.00 115.65 ? -10 DA  C "C1'" 1 
ATOM 2440 N N9    . DA  B 2 23  ? 122.862 148.268 125.827 1.00 115.65 ? -10 DA  C N9    1 
ATOM 2441 C C8    . DA  B 2 23  ? 123.741 149.263 126.175 1.00 115.65 ? -10 DA  C C8    1 
ATOM 2442 N N7    . DA  B 2 23  ? 123.835 149.459 127.467 1.00 115.65 ? -10 DA  C N7    1 
ATOM 2443 C C5    . DA  B 2 23  ? 122.959 148.530 128.009 1.00 115.65 ? -10 DA  C C5    1 
ATOM 2444 C C6    . DA  B 2 23  ? 122.602 148.229 129.335 1.00 115.65 ? -10 DA  C C6    1 
ATOM 2445 N N6    . DA  B 2 23  ? 123.098 148.865 130.398 1.00 115.65 ? -10 DA  C N6    1 
ATOM 2446 N N1    . DA  B 2 23  ? 121.706 147.238 129.534 1.00 115.65 ? -10 DA  C N1    1 
ATOM 2447 C C2    . DA  B 2 23  ? 121.212 146.598 128.467 1.00 115.65 ? -10 DA  C C2    1 
ATOM 2448 N N3    . DA  B 2 23  ? 121.469 146.789 127.175 1.00 115.65 ? -10 DA  C N3    1 
ATOM 2449 C C4    . DA  B 2 23  ? 122.361 147.781 127.011 1.00 115.65 ? -10 DA  C C4    1 
ATOM 2450 P P     . DC  B 2 24  ? 124.139 143.888 122.423 1.00 96.99  ? -9  DC  C P     1 
ATOM 2451 O OP1   . DC  B 2 24  ? 124.016 143.046 121.213 1.00 96.99  ? -9  DC  C OP1   1 
ATOM 2452 O OP2   . DC  B 2 24  ? 124.343 143.255 123.743 1.00 96.99  ? -9  DC  C OP2   1 
ATOM 2453 O "O5'" . DC  B 2 24  ? 125.326 144.936 122.199 1.00 96.99  ? -9  DC  C "O5'" 1 
ATOM 2454 C "C5'" . DC  B 2 24  ? 126.664 144.572 122.491 1.00 96.99  ? -9  DC  C "C5'" 1 
ATOM 2455 C "C4'" . DC  B 2 24  ? 127.511 145.808 122.714 1.00 96.99  ? -9  DC  C "C4'" 1 
ATOM 2456 O "O4'" . DC  B 2 24  ? 126.818 146.692 123.618 1.00 96.99  ? -9  DC  C "O4'" 1 
ATOM 2457 C "C3'" . DC  B 2 24  ? 128.859 145.553 123.363 1.00 96.99  ? -9  DC  C "C3'" 1 
ATOM 2458 O "O3'" . DC  B 2 24  ? 129.834 145.282 122.367 1.00 96.99  ? -9  DC  C "O3'" 1 
ATOM 2459 C "C2'" . DC  B 2 24  ? 129.147 146.873 124.072 1.00 96.99  ? -9  DC  C "C2'" 1 
ATOM 2460 C "C1'" . DC  B 2 24  ? 127.749 147.419 124.393 1.00 96.99  ? -9  DC  C "C1'" 1 
ATOM 2461 N N1    . DC  B 2 24  ? 127.347 147.315 125.843 1.00 96.99  ? -9  DC  C N1    1 
ATOM 2462 C C2    . DC  B 2 24  ? 128.110 147.947 126.839 1.00 96.99  ? -9  DC  C C2    1 
ATOM 2463 O O2    . DC  B 2 24  ? 129.131 148.569 126.524 1.00 96.99  ? -9  DC  C O2    1 
ATOM 2464 N N3    . DC  B 2 24  ? 127.717 147.839 128.132 1.00 96.99  ? -9  DC  C N3    1 
ATOM 2465 C C4    . DC  B 2 24  ? 126.616 147.161 128.443 1.00 96.99  ? -9  DC  C C4    1 
ATOM 2466 N N4    . DC  B 2 24  ? 126.271 147.093 129.732 1.00 96.99  ? -9  DC  C N4    1 
ATOM 2467 C C5    . DC  B 2 24  ? 125.817 146.524 127.447 1.00 96.99  ? -9  DC  C C5    1 
ATOM 2468 C C6    . DC  B 2 24  ? 126.215 146.627 126.175 1.00 96.99  ? -9  DC  C C6    1 
ATOM 2469 P P     . DG  B 2 25  ? 130.420 143.797 122.196 1.00 82.03  ? -8  DG  C P     1 
ATOM 2470 O OP1   . DG  B 2 25  ? 131.608 143.872 121.317 1.00 82.03  ? -8  DG  C OP1   1 
ATOM 2471 O OP2   . DG  B 2 25  ? 129.293 142.929 121.789 1.00 82.03  ? -8  DG  C OP2   1 
ATOM 2472 O "O5'" . DG  B 2 25  ? 130.875 143.395 123.681 1.00 82.03  ? -8  DG  C "O5'" 1 
ATOM 2473 C "C5'" . DG  B 2 25  ? 132.260 143.382 124.046 1.00 82.03  ? -8  DG  C "C5'" 1 
ATOM 2474 C "C4'" . DG  B 2 25  ? 132.858 144.776 123.983 1.00 82.03  ? -8  DG  C "C4'" 1 
ATOM 2475 O "O4'" . DG  B 2 25  ? 131.993 145.709 124.660 1.00 82.03  ? -8  DG  C "O4'" 1 
ATOM 2476 C "C3'" . DG  B 2 25  ? 134.192 144.938 124.677 1.00 82.03  ? -8  DG  C "C3'" 1 
ATOM 2477 O "O3'" . DG  B 2 25  ? 135.242 144.503 123.830 1.00 82.03  ? -8  DG  C "O3'" 1 
ATOM 2478 C "C2'" . DG  B 2 25  ? 134.234 146.446 124.892 1.00 82.03  ? -8  DG  C "C2'" 1 
ATOM 2479 C "C1'" . DG  B 2 25  ? 132.771 146.753 125.223 1.00 82.03  ? -8  DG  C "C1'" 1 
ATOM 2480 N N9    . DG  B 2 25  ? 132.507 146.824 126.659 1.00 82.03  ? -8  DG  C N9    1 
ATOM 2481 C C8    . DG  B 2 25  ? 133.310 147.406 127.611 1.00 82.03  ? -8  DG  C C8    1 
ATOM 2482 N N7    . DG  B 2 25  ? 132.829 147.325 128.818 1.00 82.03  ? -8  DG  C N7    1 
ATOM 2483 C C5    . DG  B 2 25  ? 131.627 146.650 128.662 1.00 82.03  ? -8  DG  C C5    1 
ATOM 2484 C C6    . DG  B 2 25  ? 130.667 146.273 129.625 1.00 82.03  ? -8  DG  C C6    1 
ATOM 2485 O O6    . DG  B 2 25  ? 130.690 146.469 130.846 1.00 82.03  ? -8  DG  C O6    1 
ATOM 2486 N N1    . DG  B 2 25  ? 129.596 145.602 129.049 1.00 82.03  ? -8  DG  C N1    1 
ATOM 2487 C C2    . DG  B 2 25  ? 129.466 145.331 127.710 1.00 82.03  ? -8  DG  C C2    1 
ATOM 2488 N N2    . DG  B 2 25  ? 128.360 144.678 127.340 1.00 82.03  ? -8  DG  C N2    1 
ATOM 2489 N N3    . DG  B 2 25  ? 130.356 145.680 126.796 1.00 82.03  ? -8  DG  C N3    1 
ATOM 2490 C C4    . DG  B 2 25  ? 131.411 146.332 127.340 1.00 82.03  ? -8  DG  C C4    1 
ATOM 2491 P P     . DT  B 2 26  ? 136.607 143.951 124.471 1.00 66.57  ? -7  DT  C P     1 
ATOM 2492 O OP1   . DT  B 2 26  ? 137.708 144.287 123.540 1.00 66.57  ? -7  DT  C OP1   1 
ATOM 2493 O OP2   . DT  B 2 26  ? 136.383 142.545 124.872 1.00 66.57  ? -7  DT  C OP2   1 
ATOM 2494 O "O5'" . DT  B 2 26  ? 136.774 144.823 125.802 1.00 66.57  ? -7  DT  C "O5'" 1 
ATOM 2495 C "C5'" . DT  B 2 26  ? 137.402 144.268 126.945 1.00 66.57  ? -7  DT  C "C5'" 1 
ATOM 2496 C "C4'" . DT  B 2 26  ? 137.325 145.229 128.118 1.00 66.57  ? -7  DT  C "C4'" 1 
ATOM 2497 O "O4'" . DT  B 2 26  ? 135.936 145.433 128.491 1.00 66.57  ? -7  DT  C "O4'" 1 
ATOM 2498 C "C3'" . DT  B 2 26  ? 138.044 144.759 129.378 1.00 66.57  ? -7  DT  C "C3'" 1 
ATOM 2499 O "O3'" . DT  B 2 26  ? 138.732 145.837 129.972 1.00 66.57  ? -7  DT  C "O3'" 1 
ATOM 2500 C "C2'" . DT  B 2 26  ? 136.909 144.256 130.263 1.00 66.57  ? -7  DT  C "C2'" 1 
ATOM 2501 C "C1'" . DT  B 2 26  ? 135.765 145.173 129.864 1.00 66.57  ? -7  DT  C "C1'" 1 
ATOM 2502 N N1    . DT  B 2 26  ? 134.421 144.564 130.060 1.00 66.57  ? -7  DT  C N1    1 
ATOM 2503 C C2    . DT  B 2 26  ? 133.881 144.508 131.321 1.00 66.57  ? -7  DT  C C2    1 
ATOM 2504 O O2    . DT  B 2 26  ? 134.451 144.928 132.311 1.00 66.57  ? -7  DT  C O2    1 
ATOM 2505 N N3    . DT  B 2 26  ? 132.642 143.924 131.387 1.00 66.57  ? -7  DT  C N3    1 
ATOM 2506 C C4    . DT  B 2 26  ? 131.907 143.411 130.338 1.00 66.57  ? -7  DT  C C4    1 
ATOM 2507 O O4    . DT  B 2 26  ? 130.803 142.911 130.494 1.00 66.57  ? -7  DT  C O4    1 
ATOM 2508 C C5    . DT  B 2 26  ? 132.530 143.507 129.047 1.00 66.57  ? -7  DT  C C5    1 
ATOM 2509 C C7    . DT  B 2 26  ? 131.828 142.979 127.832 1.00 66.57  ? -7  DT  C C7    1 
ATOM 2510 C C6    . DT  B 2 26  ? 133.741 144.071 128.971 1.00 66.57  ? -7  DT  C C6    1 
ATOM 2511 P P     . DA  B 2 27  ? 140.208 145.652 130.576 1.00 50.95  ? -6  DA  C P     1 
ATOM 2512 O OP1   . DA  B 2 27  ? 140.761 147.005 130.837 1.00 50.95  ? -6  DA  C OP1   1 
ATOM 2513 O OP2   . DA  B 2 27  ? 140.976 144.704 129.719 1.00 50.95  ? -6  DA  C OP2   1 
ATOM 2514 O "O5'" . DA  B 2 27  ? 139.942 144.972 131.991 1.00 50.95  ? -6  DA  C "O5'" 1 
ATOM 2515 C "C5'" . DA  B 2 27  ? 138.929 145.478 132.879 1.00 50.95  ? -6  DA  C "C5'" 1 
ATOM 2516 C "C4'" . DA  B 2 27  ? 138.461 144.371 133.792 1.00 50.95  ? -6  DA  C "C4'" 1 
ATOM 2517 O "O4'" . DA  B 2 27  ? 137.132 143.959 133.441 1.00 50.95  ? -6  DA  C "O4'" 1 
ATOM 2518 C "C3'" . DA  B 2 27  ? 139.304 143.100 133.725 1.00 50.95  ? -6  DA  C "C3'" 1 
ATOM 2519 O "O3'" . DA  B 2 27  ? 140.107 143.002 134.894 1.00 50.95  ? -6  DA  C "O3'" 1 
ATOM 2520 C "C2'" . DA  B 2 27  ? 138.286 141.972 133.722 1.00 50.95  ? -6  DA  C "C2'" 1 
ATOM 2521 C "C1'" . DA  B 2 27  ? 136.979 142.673 133.989 1.00 50.95  ? -6  DA  C "C1'" 1 
ATOM 2522 N N9    . DA  B 2 27  ? 135.831 142.041 133.360 1.00 50.95  ? -6  DA  C N9    1 
ATOM 2523 C C8    . DA  B 2 27  ? 135.686 141.608 132.069 1.00 50.95  ? -6  DA  C C8    1 
ATOM 2524 N N7    . DA  B 2 27  ? 134.521 141.059 131.825 1.00 50.95  ? -6  DA  C N7    1 
ATOM 2525 C C5    . DA  B 2 27  ? 133.869 141.107 133.049 1.00 50.95  ? -6  DA  C C5    1 
ATOM 2526 C C6    . DA  B 2 27  ? 132.596 140.688 133.456 1.00 50.95  ? -6  DA  C C6    1 
ATOM 2527 N N6    . DA  B 2 27  ? 131.716 140.097 132.647 1.00 50.95  ? -6  DA  C N6    1 
ATOM 2528 N N1    . DA  B 2 27  ? 132.254 140.890 134.745 1.00 50.95  ? -6  DA  C N1    1 
ATOM 2529 C C2    . DA  B 2 27  ? 133.133 141.481 135.554 1.00 50.95  ? -6  DA  C C2    1 
ATOM 2530 N N3    . DA  B 2 27  ? 134.352 141.929 135.287 1.00 50.95  ? -6  DA  C N3    1 
ATOM 2531 C C4    . DA  B 2 27  ? 134.667 141.703 134.003 1.00 50.95  ? -6  DA  C C4    1 
ATOM 2532 P P     . DG  B 2 28  ? 141.294 141.895 135.059 1.00 44.37  ? -5  DG  C P     1 
ATOM 2533 O OP1   . DG  B 2 28  ? 142.397 142.521 135.832 1.00 44.37  ? -5  DG  C OP1   1 
ATOM 2534 O OP2   . DG  B 2 28  ? 141.591 141.273 133.736 1.00 44.37  ? -5  DG  C OP2   1 
ATOM 2535 O "O5'" . DG  B 2 28  ? 140.628 140.795 136.002 1.00 44.37  ? -5  DG  C "O5'" 1 
ATOM 2536 C "C5'" . DG  B 2 28  ? 140.176 141.134 137.329 1.00 44.37  ? -5  DG  C "C5'" 1 
ATOM 2537 C "C4'" . DG  B 2 28  ? 139.229 140.079 137.854 1.00 44.37  ? -5  DG  C "C4'" 1 
ATOM 2538 O "O4'" . DG  B 2 28  ? 138.056 140.003 137.010 1.00 44.37  ? -5  DG  C "O4'" 1 
ATOM 2539 C "C3'" . DG  B 2 28  ? 139.806 138.659 137.915 1.00 44.37  ? -5  DG  C "C3'" 1 
ATOM 2540 O "O3'" . DG  B 2 28  ? 139.556 138.025 139.180 1.00 44.37  ? -5  DG  C "O3'" 1 
ATOM 2541 C "C2'" . DG  B 2 28  ? 139.003 137.891 136.881 1.00 44.37  ? -5  DG  C "C2'" 1 
ATOM 2542 C "C1'" . DG  B 2 28  ? 137.694 138.643 136.898 1.00 44.37  ? -5  DG  C "C1'" 1 
ATOM 2543 N N9    . DG  B 2 28  ? 136.892 138.480 135.693 1.00 44.37  ? -5  DG  C N9    1 
ATOM 2544 C C8    . DG  B 2 28  ? 137.310 138.546 134.386 1.00 44.37  ? -5  DG  C C8    1 
ATOM 2545 N N7    . DG  B 2 28  ? 136.351 138.321 133.530 1.00 44.37  ? -5  DG  C N7    1 
ATOM 2546 C C5    . DG  B 2 28  ? 135.237 138.073 134.320 1.00 44.37  ? -5  DG  C C5    1 
ATOM 2547 C C6    . DG  B 2 28  ? 133.903 137.761 133.956 1.00 44.37  ? -5  DG  C C6    1 
ATOM 2548 O O6    . DG  B 2 28  ? 133.419 137.643 132.824 1.00 44.37  ? -5  DG  C O6    1 
ATOM 2549 N N1    . DG  B 2 28  ? 133.094 137.594 135.076 1.00 44.37  ? -5  DG  C N1    1 
ATOM 2550 C C2    . DG  B 2 28  ? 133.516 137.704 136.378 1.00 44.37  ? -5  DG  C C2    1 
ATOM 2551 N N2    . DG  B 2 28  ? 132.589 137.495 137.321 1.00 44.37  ? -5  DG  C N2    1 
ATOM 2552 N N3    . DG  B 2 28  ? 134.756 137.991 136.730 1.00 44.37  ? -5  DG  C N3    1 
ATOM 2553 C C4    . DG  B 2 28  ? 135.557 138.163 135.658 1.00 44.37  ? -5  DG  C C4    1 
ATOM 2554 P P     . DG  B 2 29  ? 140.694 137.101 139.891 1.00 38.23  ? -4  DG  C P     1 
ATOM 2555 O OP1   . DG  B 2 29  ? 141.391 137.971 140.840 1.00 38.23  ? -4  DG  C OP1   1 
ATOM 2556 O OP2   . DG  B 2 29  ? 141.458 136.420 138.841 1.00 38.23  ? -4  DG  C OP2   1 
ATOM 2557 O "O5'" . DG  B 2 29  ? 139.896 135.923 140.567 1.00 38.23  ? -4  DG  C "O5'" 1 
ATOM 2558 C "C5'" . DG  B 2 29  ? 138.911 135.289 139.772 1.00 38.23  ? -4  DG  C "C5'" 1 
ATOM 2559 C "C4'" . DG  B 2 29  ? 137.855 134.679 140.653 1.00 38.23  ? -4  DG  C "C4'" 1 
ATOM 2560 O "O4'" . DG  B 2 29  ? 136.615 135.367 140.414 1.00 38.23  ? -4  DG  C "O4'" 1 
ATOM 2561 C "C3'" . DG  B 2 29  ? 137.590 133.212 140.345 1.00 38.23  ? -4  DG  C "C3'" 1 
ATOM 2562 O "O3'" . DG  B 2 29  ? 138.301 132.422 141.305 1.00 38.23  ? -4  DG  C "O3'" 1 
ATOM 2563 C "C2'" . DG  B 2 29  ? 136.085 133.097 140.484 1.00 38.23  ? -4  DG  C "C2'" 1 
ATOM 2564 C "C1'" . DG  B 2 29  ? 135.619 134.457 140.015 1.00 38.23  ? -4  DG  C "C1'" 1 
ATOM 2565 N N9    . DG  B 2 29  ? 135.461 134.581 138.573 1.00 38.23  ? -4  DG  C N9    1 
ATOM 2566 C C8    . DG  B 2 29  ? 136.355 135.127 137.690 1.00 38.23  ? -4  DG  C C8    1 
ATOM 2567 N N7    . DG  B 2 29  ? 135.932 135.109 136.457 1.00 38.23  ? -4  DG  C N7    1 
ATOM 2568 C C5    . DG  B 2 29  ? 134.676 134.527 136.535 1.00 38.23  ? -4  DG  C C5    1 
ATOM 2569 C C6    . DG  B 2 29  ? 133.745 134.226 135.519 1.00 38.23  ? -4  DG  C C6    1 
ATOM 2570 O O6    . DG  B 2 29  ? 133.833 134.441 134.304 1.00 38.23  ? -4  DG  C O6    1 
ATOM 2571 N N1    . DG  B 2 29  ? 132.608 133.616 136.033 1.00 38.23  ? -4  DG  C N1    1 
ATOM 2572 C C2    . DG  B 2 29  ? 132.398 133.330 137.354 1.00 38.23  ? -4  DG  C C2    1 
ATOM 2573 N N2    . DG  B 2 29  ? 131.232 132.742 137.655 1.00 38.23  ? -4  DG  C N2    1 
ATOM 2574 N N3    . DG  B 2 29  ? 133.260 133.606 138.313 1.00 38.23  ? -4  DG  C N3    1 
ATOM 2575 C C4    . DG  B 2 29  ? 134.371 134.198 137.834 1.00 38.23  ? -4  DG  C C4    1 
ATOM 2576 P P     . DG  B 2 30  ? 139.001 131.042 140.901 1.00 32.75  ? -3  DG  C P     1 
ATOM 2577 O OP1   . DG  B 2 30  ? 139.350 130.363 142.166 1.00 32.75  ? -3  DG  C OP1   1 
ATOM 2578 O OP2   . DG  B 2 30  ? 140.064 131.332 139.917 1.00 32.75  ? -3  DG  C OP2   1 
ATOM 2579 O "O5'" . DG  B 2 30  ? 137.812 130.221 140.215 1.00 32.75  ? -3  DG  C "O5'" 1 
ATOM 2580 C "C5'" . DG  B 2 30  ? 136.782 129.676 141.029 1.00 32.75  ? -3  DG  C "C5'" 1 
ATOM 2581 C "C4'" . DG  B 2 30  ? 135.610 129.164 140.203 1.00 32.75  ? -3  DG  C "C4'" 1 
ATOM 2582 O "O4'" . DG  B 2 30  ? 135.150 130.182 139.304 1.00 32.75  ? -3  DG  C "O4'" 1 
ATOM 2583 C "C3'" . DG  B 2 30  ? 135.914 128.004 139.281 1.00 32.75  ? -3  DG  C "C3'" 1 
ATOM 2584 O "O3'" . DG  B 2 30  ? 135.905 126.782 139.995 1.00 32.75  ? -3  DG  C "O3'" 1 
ATOM 2585 C "C2'" . DG  B 2 30  ? 134.752 128.070 138.291 1.00 32.75  ? -3  DG  C "C2'" 1 
ATOM 2586 C "C1'" . DG  B 2 30  ? 134.395 129.559 138.280 1.00 32.75  ? -3  DG  C "C1'" 1 
ATOM 2587 N N9    . DG  B 2 30  ? 134.684 130.207 137.009 1.00 32.75  ? -3  DG  C N9    1 
ATOM 2588 C C8    . DG  B 2 30  ? 135.721 131.059 136.729 1.00 32.75  ? -3  DG  C C8    1 
ATOM 2589 N N7    . DG  B 2 30  ? 135.726 131.479 135.496 1.00 32.75  ? -3  DG  C N7    1 
ATOM 2590 C C5    . DG  B 2 30  ? 134.624 130.859 134.922 1.00 32.75  ? -3  DG  C C5    1 
ATOM 2591 C C6    . DG  B 2 30  ? 134.124 130.936 133.603 1.00 32.75  ? -3  DG  C C6    1 
ATOM 2592 O O6    . DG  B 2 30  ? 134.570 131.591 132.650 1.00 32.75  ? -3  DG  C O6    1 
ATOM 2593 N N1    . DG  B 2 30  ? 132.989 130.152 133.437 1.00 32.75  ? -3  DG  C N1    1 
ATOM 2594 C C2    . DG  B 2 30  ? 132.411 129.391 134.422 1.00 32.75  ? -3  DG  C C2    1 
ATOM 2595 N N2    . DG  B 2 30  ? 131.315 128.702 134.080 1.00 32.75  ? -3  DG  C N2    1 
ATOM 2596 N N3    . DG  B 2 30  ? 132.869 129.316 135.662 1.00 32.75  ? -3  DG  C N3    1 
ATOM 2597 C C4    . DG  B 2 30  ? 133.975 130.074 135.837 1.00 32.75  ? -3  DG  C C4    1 
ATOM 2598 P P     . DG  B 2 31  ? 136.709 125.526 139.409 1.00 30.88  ? -2  DG  C P     1 
ATOM 2599 O OP1   . DG  B 2 31  ? 136.639 124.423 140.385 1.00 30.88  ? -2  DG  C OP1   1 
ATOM 2600 O OP2   . DG  B 2 31  ? 138.017 126.047 138.974 1.00 30.88  ? -2  DG  C OP2   1 
ATOM 2601 O "O5'" . DG  B 2 31  ? 135.882 125.107 138.110 1.00 30.88  ? -2  DG  C "O5'" 1 
ATOM 2602 C "C5'" . DG  B 2 31  ? 134.627 124.464 138.249 1.00 30.88  ? -2  DG  C "C5'" 1 
ATOM 2603 C "C4'" . DG  B 2 31  ? 134.026 124.128 136.892 1.00 30.88  ? -2  DG  C "C4'" 1 
ATOM 2604 O "O4'" . DG  B 2 31  ? 133.757 125.345 136.167 1.00 30.88  ? -2  DG  C "O4'" 1 
ATOM 2605 C "C3'" . DG  B 2 31  ? 134.922 123.335 135.960 1.00 30.88  ? -2  DG  C "C3'" 1 
ATOM 2606 O "O3'" . DG  B 2 31  ? 134.833 121.946 136.243 1.00 30.88  ? -2  DG  C "O3'" 1 
ATOM 2607 C "C2'" . DG  B 2 31  ? 134.324 123.654 134.594 1.00 30.88  ? -2  DG  C "C2'" 1 
ATOM 2608 C "C1'" . DG  B 2 31  ? 133.807 125.082 134.777 1.00 30.88  ? -2  DG  C "C1'" 1 
ATOM 2609 N N9    . DG  B 2 31  ? 134.643 126.091 134.132 1.00 30.88  ? -2  DG  C N9    1 
ATOM 2610 C C8    . DG  B 2 31  ? 135.749 126.717 134.653 1.00 30.88  ? -2  DG  C C8    1 
ATOM 2611 N N7    . DG  B 2 31  ? 136.287 127.577 133.837 1.00 30.88  ? -2  DG  C N7    1 
ATOM 2612 C C5    . DG  B 2 31  ? 135.487 127.514 132.701 1.00 30.88  ? -2  DG  C C5    1 
ATOM 2613 C C6    . DG  B 2 31  ? 135.580 128.219 131.481 1.00 30.88  ? -2  DG  C C6    1 
ATOM 2614 O O6    . DG  B 2 31  ? 136.417 129.070 131.150 1.00 30.88  ? -2  DG  C O6    1 
ATOM 2615 N N1    . DG  B 2 31  ? 134.567 127.851 130.594 1.00 30.88  ? -2  DG  C N1    1 
ATOM 2616 C C2    . DG  B 2 31  ? 133.592 126.917 130.865 1.00 30.88  ? -2  DG  C C2    1 
ATOM 2617 N N2    . DG  B 2 31  ? 132.694 126.689 129.901 1.00 30.88  ? -2  DG  C N2    1 
ATOM 2618 N N3    . DG  B 2 31  ? 133.497 126.257 132.004 1.00 30.88  ? -2  DG  C N3    1 
ATOM 2619 C C4    . DG  B 2 31  ? 134.474 126.604 132.870 1.00 30.88  ? -2  DG  C C4    1 
ATOM 2620 P P     . DA  B 2 32  ? 135.991 120.961 135.736 1.00 31.16  ? -1  DA  C P     1 
ATOM 2621 O OP1   . DA  B 2 32  ? 135.751 119.628 136.328 1.00 31.16  ? -1  DA  C OP1   1 
ATOM 2622 O OP2   . DA  B 2 32  ? 137.271 121.669 135.970 1.00 31.16  ? -1  DA  C OP2   1 
ATOM 2623 O "O5'" . DA  B 2 32  ? 135.762 120.858 134.154 1.00 31.16  ? -1  DA  C "O5'" 1 
ATOM 2624 C "C5'" . DA  B 2 32  ? 134.646 120.133 133.636 1.00 31.16  ? -1  DA  C "C5'" 1 
ATOM 2625 C "C4'" . DA  B 2 32  ? 134.457 120.415 132.154 1.00 31.16  ? -1  DA  C "C4'" 1 
ATOM 2626 O "O4'" . DA  B 2 32  ? 134.454 121.842 131.940 1.00 31.16  ? -1  DA  C "O4'" 1 
ATOM 2627 C "C3'" . DA  B 2 32  ? 135.555 119.881 131.253 1.00 31.16  ? -1  DA  C "C3'" 1 
ATOM 2628 O "O3'" . DA  B 2 32  ? 135.252 118.550 130.862 1.00 31.16  ? -1  DA  C "O3'" 1 
ATOM 2629 C "C2'" . DA  B 2 32  ? 135.491 120.834 130.065 1.00 31.16  ? -1  DA  C "C2'" 1 
ATOM 2630 C "C1'" . DA  B 2 32  ? 135.116 122.156 130.731 1.00 31.16  ? -1  DA  C "C1'" 1 
ATOM 2631 N N9    . DA  B 2 32  ? 136.264 123.002 131.037 1.00 31.16  ? -1  DA  C N9    1 
ATOM 2632 C C8    . DA  B 2 32  ? 137.099 122.899 132.111 1.00 31.16  ? -1  DA  C C8    1 
ATOM 2633 N N7    . DA  B 2 32  ? 138.053 123.796 132.127 1.00 31.16  ? -1  DA  C N7    1 
ATOM 2634 C C5    . DA  B 2 32  ? 137.827 124.537 130.982 1.00 31.16  ? -1  DA  C C5    1 
ATOM 2635 C C6    . DA  B 2 32  ? 138.493 125.640 130.423 1.00 31.16  ? -1  DA  C C6    1 
ATOM 2636 N N6    . DA  B 2 32  ? 139.568 126.207 130.973 1.00 31.16  ? -1  DA  C N6    1 
ATOM 2637 N N1    . DA  B 2 32  ? 138.009 126.140 129.273 1.00 31.16  ? -1  DA  C N1    1 
ATOM 2638 C C2    . DA  B 2 32  ? 136.933 125.568 128.725 1.00 31.16  ? -1  DA  C C2    1 
ATOM 2639 N N3    . DA  B 2 32  ? 136.226 124.532 129.157 1.00 31.16  ? -1  DA  C N3    1 
ATOM 2640 C C4    . DA  B 2 32  ? 136.728 124.060 130.301 1.00 31.16  ? -1  DA  C C4    1 
ATOM 2641 P P     . DG  B 2 33  ? 136.426 117.474 130.656 1.00 39.61  ? 0   DG  C P     1 
ATOM 2642 O OP1   . DG  B 2 33  ? 137.657 118.177 130.234 1.00 39.61  ? 0   DG  C OP1   1 
ATOM 2643 O OP2   . DG  B 2 33  ? 135.870 116.399 129.807 1.00 39.61  ? 0   DG  C OP2   1 
ATOM 2644 O "O5'" . DG  B 2 33  ? 136.650 116.868 132.116 1.00 39.61  ? 0   DG  C "O5'" 1 
ATOM 2645 C "C5'" . DG  B 2 33  ? 136.488 115.474 132.333 1.00 39.61  ? 0   DG  C "C5'" 1 
ATOM 2646 C "C4'" . DG  B 2 33  ? 137.726 114.711 131.901 1.00 39.61  ? 0   DG  C "C4'" 1 
ATOM 2647 O "O4'" . DG  B 2 33  ? 138.627 114.605 133.028 1.00 39.61  ? 0   DG  C "O4'" 1 
ATOM 2648 C "C3'" . DG  B 2 33  ? 137.464 113.280 131.459 1.00 39.61  ? 0   DG  C "C3'" 1 
ATOM 2649 O "O3'" . DG  B 2 33  ? 138.452 112.843 130.532 1.00 39.61  ? 0   DG  C "O3'" 1 
ATOM 2650 C "C2'" . DG  B 2 33  ? 137.549 112.517 132.766 1.00 39.61  ? 0   DG  C "C2'" 1 
ATOM 2651 C "C1'" . DG  B 2 33  ? 138.625 113.284 133.526 1.00 39.61  ? 0   DG  C "C1'" 1 
ATOM 2652 N N9    . DG  B 2 33  ? 138.375 113.322 134.959 1.00 39.61  ? 0   DG  C N9    1 
ATOM 2653 C C8    . DG  B 2 33  ? 137.178 113.577 135.579 1.00 39.61  ? 0   DG  C C8    1 
ATOM 2654 N N7    . DG  B 2 33  ? 137.246 113.528 136.878 1.00 39.61  ? 0   DG  C N7    1 
ATOM 2655 C C5    . DG  B 2 33  ? 138.571 113.210 137.135 1.00 39.61  ? 0   DG  C C5    1 
ATOM 2656 C C6    . DG  B 2 33  ? 139.240 113.022 138.367 1.00 39.61  ? 0   DG  C C6    1 
ATOM 2657 O O6    . DG  B 2 33  ? 138.776 113.101 139.513 1.00 39.61  ? 0   DG  C O6    1 
ATOM 2658 N N1    . DG  B 2 33  ? 140.583 112.712 138.178 1.00 39.61  ? 0   DG  C N1    1 
ATOM 2659 C C2    . DG  B 2 33  ? 141.199 112.600 136.956 1.00 39.61  ? 0   DG  C C2    1 
ATOM 2660 N N2    . DG  B 2 33  ? 142.503 112.295 136.976 1.00 39.61  ? 0   DG  C N2    1 
ATOM 2661 N N3    . DG  B 2 33  ? 140.584 112.775 135.798 1.00 39.61  ? 0   DG  C N3    1 
ATOM 2662 C C4    . DG  B 2 33  ? 139.277 113.075 135.962 1.00 39.61  ? 0   DG  C C4    1 
ATOM 2663 P P     . DA  B 2 34  ? 138.211 111.501 129.679 1.00 41.65  ? 1   DA  C P     1 
ATOM 2664 O OP1   . DA  B 2 34  ? 138.756 111.728 128.324 1.00 41.65  ? 1   DA  C OP1   1 
ATOM 2665 O OP2   . DA  B 2 34  ? 136.799 111.093 129.857 1.00 41.65  ? 1   DA  C OP2   1 
ATOM 2666 O "O5'" . DA  B 2 34  ? 139.115 110.407 130.413 1.00 41.65  ? 1   DA  C "O5'" 1 
ATOM 2667 C "C5'" . DA  B 2 34  ? 140.524 110.580 130.491 1.00 41.65  ? 1   DA  C "C5'" 1 
ATOM 2668 C "C4'" . DA  B 2 34  ? 141.129 109.637 131.516 1.00 41.65  ? 1   DA  C "C4'" 1 
ATOM 2669 O "O4'" . DA  B 2 34  ? 140.480 109.832 132.801 1.00 41.65  ? 1   DA  C "O4'" 1 
ATOM 2670 C "C3'" . DA  B 2 34  ? 140.984 108.151 131.199 1.00 41.65  ? 1   DA  C "C3'" 1 
ATOM 2671 O "O3'" . DA  B 2 34  ? 142.140 107.452 131.640 1.00 41.65  ? 1   DA  C "O3'" 1 
ATOM 2672 C "C2'" . DA  B 2 34  ? 139.754 107.756 132.008 1.00 41.65  ? 1   DA  C "C2'" 1 
ATOM 2673 C "C1'" . DA  B 2 34  ? 139.935 108.609 133.251 1.00 41.65  ? 1   DA  C "C1'" 1 
ATOM 2674 N N9    . DA  B 2 34  ? 138.687 108.889 133.953 1.00 41.65  ? 1   DA  C N9    1 
ATOM 2675 C C8    . DA  B 2 34  ? 137.496 109.253 133.397 1.00 41.65  ? 1   DA  C C8    1 
ATOM 2676 N N7    . DA  B 2 34  ? 136.543 109.450 134.271 1.00 41.65  ? 1   DA  C N7    1 
ATOM 2677 C C5    . DA  B 2 34  ? 137.149 109.194 135.488 1.00 41.65  ? 1   DA  C C5    1 
ATOM 2678 C C6    . DA  B 2 34  ? 136.669 109.223 136.813 1.00 41.65  ? 1   DA  C C6    1 
ATOM 2679 N N6    . DA  B 2 34  ? 135.410 109.540 137.133 1.00 41.65  ? 1   DA  C N6    1 
ATOM 2680 N N1    . DA  B 2 34  ? 137.535 108.911 137.797 1.00 41.65  ? 1   DA  C N1    1 
ATOM 2681 C C2    . DA  B 2 34  ? 138.791 108.598 137.472 1.00 41.65  ? 1   DA  C C2    1 
ATOM 2682 N N3    . DA  B 2 34  ? 139.354 108.532 136.268 1.00 41.65  ? 1   DA  C N3    1 
ATOM 2683 C C4    . DA  B 2 34  ? 138.470 108.846 135.311 1.00 41.65  ? 1   DA  C C4    1 
ATOM 2684 P P     . DA  B 2 35  ? 142.488 105.996 131.054 1.00 49.73  ? 2   DA  C P     1 
ATOM 2685 O OP1   . DA  B 2 35  ? 143.727 106.126 130.258 1.00 49.73  ? 2   DA  C OP1   1 
ATOM 2686 O OP2   . DA  B 2 35  ? 141.266 105.443 130.428 1.00 49.73  ? 2   DA  C OP2   1 
ATOM 2687 O "O5'" . DA  B 2 35  ? 142.810 105.129 132.360 1.00 49.73  ? 2   DA  C "O5'" 1 
ATOM 2688 C "C5'" . DA  B 2 35  ? 143.915 105.478 133.186 1.00 49.73  ? 2   DA  C "C5'" 1 
ATOM 2689 C "C4'" . DA  B 2 35  ? 143.757 104.900 134.583 1.00 49.73  ? 2   DA  C "C4'" 1 
ATOM 2690 O "O4'" . DA  B 2 35  ? 142.604 105.496 135.237 1.00 49.73  ? 2   DA  C "O4'" 1 
ATOM 2691 C "C3'" . DA  B 2 35  ? 143.546 103.383 134.644 1.00 49.73  ? 2   DA  C "C3'" 1 
ATOM 2692 O "O3'" . DA  B 2 35  ? 144.406 102.815 135.627 1.00 49.73  ? 2   DA  C "O3'" 1 
ATOM 2693 C "C2'" . DA  B 2 35  ? 142.075 103.246 135.041 1.00 49.73  ? 2   DA  C "C2'" 1 
ATOM 2694 C "C1'" . DA  B 2 35  ? 141.883 104.485 135.895 1.00 49.73  ? 2   DA  C "C1'" 1 
ATOM 2695 N N9    . DA  B 2 35  ? 140.492 104.909 136.025 1.00 49.73  ? 2   DA  C N9    1 
ATOM 2696 C C8    . DA  B 2 35  ? 139.686 105.410 135.041 1.00 49.73  ? 2   DA  C C8    1 
ATOM 2697 N N7    . DA  B 2 35  ? 138.476 105.711 135.452 1.00 49.73  ? 2   DA  C N7    1 
ATOM 2698 C C5    . DA  B 2 35  ? 138.494 105.394 136.801 1.00 49.73  ? 2   DA  C C5    1 
ATOM 2699 C C6    . DA  B 2 35  ? 137.515 105.488 137.811 1.00 49.73  ? 2   DA  C C6    1 
ATOM 2700 N N6    . DA  B 2 35  ? 136.283 105.949 137.597 1.00 49.73  ? 2   DA  C N6    1 
ATOM 2701 N N1    . DA  B 2 35  ? 137.855 105.090 139.048 1.00 49.73  ? 2   DA  C N1    1 
ATOM 2702 C C2    . DA  B 2 35  ? 139.097 104.637 139.261 1.00 49.73  ? 2   DA  C C2    1 
ATOM 2703 N N3    . DA  B 2 35  ? 140.100 104.500 138.395 1.00 49.73  ? 2   DA  C N3    1 
ATOM 2704 C C4    . DA  B 2 35  ? 139.730 104.904 137.171 1.00 49.73  ? 2   DA  C C4    1 
ATOM 2705 P P     . DT  B 2 36  ? 144.886 101.286 135.507 1.00 51.77  ? 3   DT  C P     1 
ATOM 2706 O OP1   . DT  B 2 36  ? 145.826 101.030 136.619 1.00 51.77  ? 3   DT  C OP1   1 
ATOM 2707 O OP2   . DT  B 2 36  ? 145.318 101.054 134.111 1.00 51.77  ? 3   DT  C OP2   1 
ATOM 2708 O "O5'" . DT  B 2 36  ? 143.548 100.443 135.739 1.00 51.77  ? 3   DT  C "O5'" 1 
ATOM 2709 C "C5'" . DT  B 2 36  ? 143.539 99.350  136.649 1.00 51.77  ? 3   DT  C "C5'" 1 
ATOM 2710 C "C4'" . DT  B 2 36  ? 143.284 99.829  138.067 1.00 51.77  ? 3   DT  C "C4'" 1 
ATOM 2711 O "O4'" . DT  B 2 36  ? 142.282 100.884 138.050 1.00 51.77  ? 3   DT  C "O4'" 1 
ATOM 2712 C "C3'" . DT  B 2 36  ? 142.747 98.763  139.020 1.00 51.77  ? 3   DT  C "C3'" 1 
ATOM 2713 O "O3'" . DT  B 2 36  ? 143.246 98.988  140.333 1.00 51.77  ? 3   DT  C "O3'" 1 
ATOM 2714 C "C2'" . DT  B 2 36  ? 141.247 99.003  138.952 1.00 51.77  ? 3   DT  C "C2'" 1 
ATOM 2715 C "C1'" . DT  B 2 36  ? 141.210 100.516 138.889 1.00 51.77  ? 3   DT  C "C1'" 1 
ATOM 2716 N N1    . DT  B 2 36  ? 139.943 101.097 138.338 1.00 51.77  ? 3   DT  C N1    1 
ATOM 2717 C C2    . DT  B 2 36  ? 138.892 101.351 139.192 1.00 51.77  ? 3   DT  C C2    1 
ATOM 2718 O O2    . DT  B 2 36  ? 138.923 101.099 140.383 1.00 51.77  ? 3   DT  C O2    1 
ATOM 2719 N N3    . DT  B 2 36  ? 137.787 101.901 138.592 1.00 51.77  ? 3   DT  C N3    1 
ATOM 2720 C C4    . DT  B 2 36  ? 137.636 102.230 137.264 1.00 51.77  ? 3   DT  C C4    1 
ATOM 2721 O O4    . DT  B 2 36  ? 136.606 102.721 136.824 1.00 51.77  ? 3   DT  C O4    1 
ATOM 2722 C C5    . DT  B 2 36  ? 138.776 101.951 136.425 1.00 51.77  ? 3   DT  C C5    1 
ATOM 2723 C C7    . DT  B 2 36  ? 138.721 102.263 134.963 1.00 51.77  ? 3   DT  C C7    1 
ATOM 2724 C C6    . DT  B 2 36  ? 139.866 101.412 136.996 1.00 51.77  ? 3   DT  C C6    1 
ATOM 2725 P P     . DT  B 2 37  ? 143.393 97.766  141.367 1.00 53.22  ? 4   DT  C P     1 
ATOM 2726 O OP1   . DT  B 2 37  ? 144.206 98.247  142.505 1.00 53.22  ? 4   DT  C OP1   1 
ATOM 2727 O OP2   . DT  B 2 37  ? 143.841 96.585  140.597 1.00 53.22  ? 4   DT  C OP2   1 
ATOM 2728 O "O5'" . DT  B 2 37  ? 141.893 97.493  141.868 1.00 53.22  ? 4   DT  C "O5'" 1 
ATOM 2729 C "C5'" . DT  B 2 37  ? 141.161 98.523  142.534 1.00 53.22  ? 4   DT  C "C5'" 1 
ATOM 2730 C "C4'" . DT  B 2 37  ? 139.852 97.994  143.110 1.00 53.22  ? 4   DT  C "C4'" 1 
ATOM 2731 O "O4'" . DT  B 2 37  ? 138.727 98.623  142.437 1.00 53.22  ? 4   DT  C "O4'" 1 
ATOM 2732 C "C3'" . DT  B 2 37  ? 139.617 96.497  142.948 1.00 53.22  ? 4   DT  C "C3'" 1 
ATOM 2733 O "O3'" . DT  B 2 37  ? 138.759 96.051  143.981 1.00 53.22  ? 4   DT  C "O3'" 1 
ATOM 2734 C "C2'" . DT  B 2 37  ? 138.901 96.456  141.611 1.00 53.22  ? 4   DT  C "C2'" 1 
ATOM 2735 C "C1'" . DT  B 2 37  ? 137.957 97.627  141.796 1.00 53.22  ? 4   DT  C "C1'" 1 
ATOM 2736 N N1    . DT  B 2 37  ? 137.427 98.187  140.536 1.00 53.22  ? 4   DT  C N1    1 
ATOM 2737 C C2    . DT  B 2 37  ? 136.247 98.866  140.565 1.00 53.22  ? 4   DT  C C2    1 
ATOM 2738 O O2    . DT  B 2 37  ? 135.598 99.029  141.580 1.00 53.22  ? 4   DT  C O2    1 
ATOM 2739 N N3    . DT  B 2 37  ? 135.838 99.351  139.357 1.00 53.22  ? 4   DT  C N3    1 
ATOM 2740 C C4    . DT  B 2 37  ? 136.484 99.226  138.146 1.00 53.22  ? 4   DT  C C4    1 
ATOM 2741 O O4    . DT  B 2 37  ? 136.032 99.701  137.111 1.00 53.22  ? 4   DT  C O4    1 
ATOM 2742 C C5    . DT  B 2 37  ? 137.723 98.501  138.186 1.00 53.22  ? 4   DT  C C5    1 
ATOM 2743 C C7    . DT  B 2 37  ? 138.512 98.296  136.932 1.00 53.22  ? 4   DT  C C7    1 
ATOM 2744 C C6    . DT  B 2 37  ? 138.128 98.020  139.365 1.00 53.22  ? 4   DT  C C6    1 
ATOM 2745 P P     . DG  B 2 38  ? 139.296 94.940  145.034 1.00 58.54  ? 5   DG  C P     1 
ATOM 2746 O OP1   . DG  B 2 38  ? 140.379 95.548  145.852 1.00 58.54  ? 5   DG  C OP1   1 
ATOM 2747 O OP2   . DG  B 2 38  ? 139.546 93.673  144.297 1.00 58.54  ? 5   DG  C OP2   1 
ATOM 2748 O "O5'" . DG  B 2 38  ? 138.052 94.694  145.996 1.00 58.54  ? 5   DG  C "O5'" 1 
ATOM 2749 C "C5'" . DG  B 2 38  ? 137.359 95.788  146.616 1.00 58.54  ? 5   DG  C "C5'" 1 
ATOM 2750 C "C4'" . DG  B 2 38  ? 135.866 95.598  146.483 1.00 58.54  ? 5   DG  C "C4'" 1 
ATOM 2751 O "O4'" . DG  B 2 38  ? 135.441 96.039  145.174 1.00 58.54  ? 5   DG  C "O4'" 1 
ATOM 2752 C "C3'" . DG  B 2 38  ? 135.373 94.155  146.614 1.00 58.54  ? 5   DG  C "C3'" 1 
ATOM 2753 O "O3'" . DG  B 2 38  ? 134.060 94.133  147.194 1.00 58.54  ? 5   DG  C "O3'" 1 
ATOM 2754 C "C2'" . DG  B 2 38  ? 135.252 93.707  145.171 1.00 58.54  ? 5   DG  C "C2'" 1 
ATOM 2755 C "C1'" . DG  B 2 38  ? 134.755 94.982  144.525 1.00 58.54  ? 5   DG  C "C1'" 1 
ATOM 2756 N N9    . DG  B 2 38  ? 135.012 95.097  143.097 1.00 58.54  ? 5   DG  C N9    1 
ATOM 2757 C C8    . DG  B 2 38  ? 136.032 94.531  142.371 1.00 58.54  ? 5   DG  C C8    1 
ATOM 2758 N N7    . DG  B 2 38  ? 135.985 94.832  141.102 1.00 58.54  ? 5   DG  C N7    1 
ATOM 2759 C C5    . DG  B 2 38  ? 134.869 95.650  140.985 1.00 58.54  ? 5   DG  C C5    1 
ATOM 2760 C C6    . DG  B 2 38  ? 134.304 96.278  139.846 1.00 58.54  ? 5   DG  C C6    1 
ATOM 2761 O O6    . DG  B 2 38  ? 134.699 96.249  138.674 1.00 58.54  ? 5   DG  C O6    1 
ATOM 2762 N N1    . DG  B 2 38  ? 133.171 97.012  140.179 1.00 58.54  ? 5   DG  C N1    1 
ATOM 2763 C C2    . DG  B 2 38  ? 132.643 97.124  141.442 1.00 58.54  ? 5   DG  C C2    1 
ATOM 2764 N N2    . DG  B 2 38  ? 131.537 97.871  141.561 1.00 58.54  ? 5   DG  C N2    1 
ATOM 2765 N N3    . DG  B 2 38  ? 133.155 96.536  142.508 1.00 58.54  ? 5   DG  C N3    1 
ATOM 2766 C C4    . DG  B 2 38  ? 134.261 95.825  142.209 1.00 58.54  ? 5   DG  C C4    1 
ATOM 2767 P P     . DG  B 2 39  ? 133.845 94.434  148.773 1.00 61.52  ? 6   DG  C P     1 
ATOM 2768 O OP1   . DG  B 2 39  ? 134.250 95.834  149.028 1.00 61.52  ? 6   DG  C OP1   1 
ATOM 2769 O OP2   . DG  B 2 39  ? 134.492 93.334  149.519 1.00 61.52  ? 6   DG  C OP2   1 
ATOM 2770 O "O5'" . DG  B 2 39  ? 132.271 94.332  149.016 1.00 61.52  ? 6   DG  C "O5'" 1 
ATOM 2771 C "C5'" . DG  B 2 39  ? 131.378 94.711  147.977 1.00 61.52  ? 6   DG  C "C5'" 1 
ATOM 2772 C "C4'" . DG  B 2 39  ? 130.626 93.505  147.448 1.00 61.52  ? 6   DG  C "C4'" 1 
ATOM 2773 O "O4'" . DG  B 2 39  ? 130.506 93.602  146.013 1.00 61.52  ? 6   DG  C "O4'" 1 
ATOM 2774 C "C3'" . DG  B 2 39  ? 131.309 92.172  147.676 1.00 61.52  ? 6   DG  C "C3'" 1 
ATOM 2775 O "O3'" . DG  B 2 39  ? 131.013 91.691  148.981 1.00 61.52  ? 6   DG  C "O3'" 1 
ATOM 2776 C "C2'" . DG  B 2 39  ? 130.666 91.304  146.600 1.00 61.52  ? 6   DG  C "C2'" 1 
ATOM 2777 C "C1'" . DG  B 2 39  ? 130.460 92.301  145.454 1.00 61.52  ? 6   DG  C "C1'" 1 
ATOM 2778 N N9    . DG  B 2 39  ? 131.474 92.206  144.411 1.00 61.52  ? 6   DG  C N9    1 
ATOM 2779 C C8    . DG  B 2 39  ? 132.606 91.427  144.428 1.00 61.52  ? 6   DG  C C8    1 
ATOM 2780 N N7    . DG  B 2 39  ? 133.331 91.541  143.351 1.00 61.52  ? 6   DG  C N7    1 
ATOM 2781 C C5    . DG  B 2 39  ? 132.635 92.451  142.568 1.00 61.52  ? 6   DG  C C5    1 
ATOM 2782 C C6    . DG  B 2 39  ? 132.936 92.965  141.287 1.00 61.52  ? 6   DG  C C6    1 
ATOM 2783 O O6    . DG  B 2 39  ? 133.912 92.711  140.569 1.00 61.52  ? 6   DG  C O6    1 
ATOM 2784 N N1    . DG  B 2 39  ? 131.966 93.866  140.852 1.00 61.52  ? 6   DG  C N1    1 
ATOM 2785 C C2    . DG  B 2 39  ? 130.846 94.221  141.567 1.00 61.52  ? 6   DG  C C2    1 
ATOM 2786 N N2    . DG  B 2 39  ? 130.023 95.104  140.984 1.00 61.52  ? 6   DG  C N2    1 
ATOM 2787 N N3    . DG  B 2 39  ? 130.552 93.745  142.770 1.00 61.52  ? 6   DG  C N3    1 
ATOM 2788 C C4    . DG  B 2 39  ? 131.488 92.868  143.207 1.00 61.52  ? 6   DG  C C4    1 
ATOM 2789 P P     . C   C 3 7   ? 134.380 115.005 100.368 1.00 32.22  ? -19 C   B P     1 
ATOM 2790 O OP1   . C   C 3 7   ? 133.129 114.211 100.433 1.00 32.22  ? -19 C   B OP1   1 
ATOM 2791 O OP2   . C   C 3 7   ? 134.835 115.569 99.072  1.00 32.22  ? -19 C   B OP2   1 
ATOM 2792 O "O5'" . C   C 3 7   ? 134.242 116.198 101.408 1.00 32.22  ? -19 C   B "O5'" 1 
ATOM 2793 C "C5'" . C   C 3 7   ? 132.972 116.547 101.936 1.00 32.22  ? -19 C   B "C5'" 1 
ATOM 2794 C "C4'" . C   C 3 7   ? 132.849 116.153 103.384 1.00 32.22  ? -19 C   B "C4'" 1 
ATOM 2795 O "O4'" . C   C 3 7   ? 133.885 116.828 104.140 1.00 32.22  ? -19 C   B "O4'" 1 
ATOM 2796 C "C3'" . C   C 3 7   ? 131.529 116.544 104.030 1.00 32.22  ? -19 C   B "C3'" 1 
ATOM 2797 O "O3'" . C   C 3 7   ? 131.146 115.571 104.992 1.00 32.22  ? -19 C   B "O3'" 1 
ATOM 2798 C "C2'" . C   C 3 7   ? 131.860 117.868 104.704 1.00 32.22  ? -19 C   B "C2'" 1 
ATOM 2799 O "O2'" . C   C 3 7   ? 131.034 118.191 105.803 1.00 32.22  ? -19 C   B "O2'" 1 
ATOM 2800 C "C1'" . C   C 3 7   ? 133.301 117.644 105.133 1.00 32.22  ? -19 C   B "C1'" 1 
ATOM 2801 N N1    . C   C 3 7   ? 134.103 118.868 105.229 1.00 32.22  ? -19 C   B N1    1 
ATOM 2802 C C2    . C   C 3 7   ? 133.917 119.744 106.293 1.00 32.22  ? -19 C   B C2    1 
ATOM 2803 O O2    . C   C 3 7   ? 133.045 119.493 107.137 1.00 32.22  ? -19 C   B O2    1 
ATOM 2804 N N3    . C   C 3 7   ? 134.677 120.855 106.373 1.00 32.22  ? -19 C   B N3    1 
ATOM 2805 C C4    . C   C 3 7   ? 135.604 121.093 105.452 1.00 32.22  ? -19 C   B C4    1 
ATOM 2806 N N4    . C   C 3 7   ? 136.334 122.200 105.568 1.00 32.22  ? -19 C   B N4    1 
ATOM 2807 C C5    . C   C 3 7   ? 135.822 120.207 104.365 1.00 32.22  ? -19 C   B C5    1 
ATOM 2808 C C6    . C   C 3 7   ? 135.060 119.113 104.296 1.00 32.22  ? -19 C   B C6    1 
ATOM 2809 P P     . U   C 3 8   ? 129.972 114.533 104.644 1.00 28.51  ? -18 U   B P     1 
ATOM 2810 O OP1   . U   C 3 8   ? 129.797 113.622 105.801 1.00 28.51  ? -18 U   B OP1   1 
ATOM 2811 O OP2   . U   C 3 8   ? 130.232 113.973 103.297 1.00 28.51  ? -18 U   B OP2   1 
ATOM 2812 O "O5'" . U   C 3 8   ? 128.672 115.441 104.548 1.00 28.51  ? -18 U   B "O5'" 1 
ATOM 2813 C "C5'" . U   C 3 8   ? 128.385 116.388 105.566 1.00 28.51  ? -18 U   B "C5'" 1 
ATOM 2814 C "C4'" . U   C 3 8   ? 126.919 116.697 105.656 1.00 28.51  ? -18 U   B "C4'" 1 
ATOM 2815 O "O4'" . U   C 3 8   ? 126.174 115.450 105.684 1.00 28.51  ? -18 U   B "O4'" 1 
ATOM 2816 C "C3'" . U   C 3 8   ? 126.513 117.458 106.914 1.00 28.51  ? -18 U   B "C3'" 1 
ATOM 2817 O "O3'" . U   C 3 8   ? 125.378 118.272 106.621 1.00 28.51  ? -18 U   B "O3'" 1 
ATOM 2818 C "C2'" . U   C 3 8   ? 126.098 116.331 107.850 1.00 28.51  ? -18 U   B "C2'" 1 
ATOM 2819 O "O2'" . U   C 3 8   ? 125.239 116.719 108.901 1.00 28.51  ? -18 U   B "O2'" 1 
ATOM 2820 C "C1'" . U   C 3 8   ? 125.412 115.383 106.873 1.00 28.51  ? -18 U   B "C1'" 1 
ATOM 2821 N N1    . U   C 3 8   ? 125.351 113.986 107.325 1.00 28.51  ? -18 U   B N1    1 
ATOM 2822 C C2    . U   C 3 8   ? 124.093 113.470 107.581 1.00 28.51  ? -18 U   B C2    1 
ATOM 2823 O O2    . U   C 3 8   ? 123.072 114.117 107.446 1.00 28.51  ? -18 U   B O2    1 
ATOM 2824 N N3    . U   C 3 8   ? 124.080 112.168 108.003 1.00 28.51  ? -18 U   B N3    1 
ATOM 2825 C C4    . U   C 3 8   ? 125.172 111.353 108.191 1.00 28.51  ? -18 U   B C4    1 
ATOM 2826 O O4    . U   C 3 8   ? 124.993 110.199 108.575 1.00 28.51  ? -18 U   B O4    1 
ATOM 2827 C C5    . U   C 3 8   ? 126.435 111.958 107.906 1.00 28.51  ? -18 U   B C5    1 
ATOM 2828 C C6    . U   C 3 8   ? 126.485 113.224 107.492 1.00 28.51  ? -18 U   B C6    1 
ATOM 2829 P P     . U   C 3 9   ? 125.226 119.728 107.279 1.00 29.47  ? -17 U   B P     1 
ATOM 2830 O OP1   . U   C 3 9   ? 124.345 120.544 106.416 1.00 29.47  ? -17 U   B OP1   1 
ATOM 2831 O OP2   . U   C 3 9   ? 126.579 120.217 107.626 1.00 29.47  ? -17 U   B OP2   1 
ATOM 2832 O "O5'" . U   C 3 9   ? 124.445 119.458 108.635 1.00 29.47  ? -17 U   B "O5'" 1 
ATOM 2833 C "C5'" . U   C 3 9   ? 123.099 119.014 108.631 1.00 29.47  ? -17 U   B "C5'" 1 
ATOM 2834 C "C4'" . U   C 3 9   ? 122.521 119.017 110.023 1.00 29.47  ? -17 U   B "C4'" 1 
ATOM 2835 O "O4'" . U   C 3 9   ? 123.478 118.437 110.952 1.00 29.47  ? -17 U   B "O4'" 1 
ATOM 2836 C "C3'" . U   C 3 9   ? 122.230 120.382 110.616 1.00 29.47  ? -17 U   B "C3'" 1 
ATOM 2837 O "O3'" . U   C 3 9   ? 121.023 120.960 110.155 1.00 29.47  ? -17 U   B "O3'" 1 
ATOM 2838 C "C2'" . U   C 3 9   ? 122.253 120.095 112.106 1.00 29.47  ? -17 U   B "C2'" 1 
ATOM 2839 O "O2'" . U   C 3 9   ? 121.071 119.413 112.498 1.00 29.47  ? -17 U   B "O2'" 1 
ATOM 2840 C "C1'" . U   C 3 9   ? 123.421 119.118 112.188 1.00 29.47  ? -17 U   B "C1'" 1 
ATOM 2841 N N1    . U   C 3 9   ? 124.705 119.826 112.375 1.00 29.47  ? -17 U   B N1    1 
ATOM 2842 C C2    . U   C 3 9   ? 124.923 120.558 113.520 1.00 29.47  ? -17 U   B C2    1 
ATOM 2843 O O2    . U   C 3 9   ? 124.115 120.673 114.426 1.00 29.47  ? -17 U   B O2    1 
ATOM 2844 N N3    . U   C 3 9   ? 126.141 121.178 113.580 1.00 29.47  ? -17 U   B N3    1 
ATOM 2845 C C4    . U   C 3 9   ? 127.146 121.137 112.641 1.00 29.47  ? -17 U   B C4    1 
ATOM 2846 O O4    . U   C 3 9   ? 128.185 121.753 112.846 1.00 29.47  ? -17 U   B O4    1 
ATOM 2847 C C5    . U   C 3 9   ? 126.845 120.359 111.491 1.00 29.47  ? -17 U   B C5    1 
ATOM 2848 C C6    . U   C 3 9   ? 125.667 119.751 111.408 1.00 29.47  ? -17 U   B C6    1 
ATOM 2849 P P     . G   C 3 10  ? 121.028 122.426 109.467 1.00 30.90  ? -16 G   B P     1 
ATOM 2850 O OP1   . G   C 3 10  ? 119.626 122.774 109.144 1.00 30.90  ? -16 G   B OP1   1 
ATOM 2851 O OP2   . G   C 3 10  ? 122.048 122.441 108.382 1.00 30.90  ? -16 G   B OP2   1 
ATOM 2852 O "O5'" . G   C 3 10  ? 121.522 123.391 110.638 1.00 30.90  ? -16 G   B "O5'" 1 
ATOM 2853 C "C5'" . G   C 3 10  ? 120.728 123.559 111.826 1.00 30.90  ? -16 G   B "C5'" 1 
ATOM 2854 C "C4'" . G   C 3 10  ? 121.575 123.997 113.000 1.00 30.90  ? -16 G   B "C4'" 1 
ATOM 2855 O "O4'" . G   C 3 10  ? 122.736 123.133 113.155 1.00 30.90  ? -16 G   B "O4'" 1 
ATOM 2856 C "C3'" . G   C 3 10  ? 122.208 125.373 112.916 1.00 30.90  ? -16 G   B "C3'" 1 
ATOM 2857 O "O3'" . G   C 3 10  ? 121.314 126.445 113.147 1.00 30.90  ? -16 G   B "O3'" 1 
ATOM 2858 C "C2'" . G   C 3 10  ? 123.250 125.267 114.012 1.00 30.90  ? -16 G   B "C2'" 1 
ATOM 2859 O "O2'" . G   C 3 10  ? 122.700 125.311 115.313 1.00 30.90  ? -16 G   B "O2'" 1 
ATOM 2860 C "C1'" . G   C 3 10  ? 123.811 123.882 113.710 1.00 30.90  ? -16 G   B "C1'" 1 
ATOM 2861 N N9    . G   C 3 10  ? 124.870 123.976 112.713 1.00 30.90  ? -16 G   B N9    1 
ATOM 2862 C C8    . G   C 3 10  ? 124.896 123.409 111.462 1.00 30.90  ? -16 G   B C8    1 
ATOM 2863 N N7    . G   C 3 10  ? 125.976 123.702 110.790 1.00 30.90  ? -16 G   B N7    1 
ATOM 2864 C C5    . G   C 3 10  ? 126.697 124.527 111.643 1.00 30.90  ? -16 G   B C5    1 
ATOM 2865 C C6    . G   C 3 10  ? 127.947 125.171 111.459 1.00 30.90  ? -16 G   B C6    1 
ATOM 2866 O O6    . G   C 3 10  ? 128.703 125.121 110.484 1.00 30.90  ? -16 G   B O6    1 
ATOM 2867 N N1    . G   C 3 10  ? 128.306 125.917 112.576 1.00 30.90  ? -16 G   B N1    1 
ATOM 2868 C C2    . G   C 3 10  ? 127.559 126.036 113.720 1.00 30.90  ? -16 G   B C2    1 
ATOM 2869 N N2    . G   C 3 10  ? 128.077 126.806 114.688 1.00 30.90  ? -16 G   B N2    1 
ATOM 2870 N N3    . G   C 3 10  ? 126.391 125.446 113.903 1.00 30.90  ? -16 G   B N3    1 
ATOM 2871 C C4    . G   C 3 10  ? 126.022 124.715 112.829 1.00 30.90  ? -16 G   B C4    1 
ATOM 2872 P P     . C   C 3 11  ? 121.184 127.654 112.092 1.00 34.64  ? -15 C   B P     1 
ATOM 2873 O OP1   . C   C 3 11  ? 119.896 128.322 112.386 1.00 34.64  ? -15 C   B OP1   1 
ATOM 2874 O OP2   . C   C 3 11  ? 121.456 127.151 110.722 1.00 34.64  ? -15 C   B OP2   1 
ATOM 2875 O "O5'" . C   C 3 11  ? 122.356 128.655 112.489 1.00 34.64  ? -15 C   B "O5'" 1 
ATOM 2876 C "C5'" . C   C 3 11  ? 122.335 129.314 113.744 1.00 34.64  ? -15 C   B "C5'" 1 
ATOM 2877 C "C4'" . C   C 3 11  ? 123.557 130.172 113.948 1.00 34.64  ? -15 C   B "C4'" 1 
ATOM 2878 O "O4'" . C   C 3 11  ? 124.753 129.352 113.894 1.00 34.64  ? -15 C   B "O4'" 1 
ATOM 2879 C "C3'" . C   C 3 11  ? 123.799 131.248 112.906 1.00 34.64  ? -15 C   B "C3'" 1 
ATOM 2880 O "O3'" . C   C 3 11  ? 123.023 132.413 113.128 1.00 34.64  ? -15 C   B "O3'" 1 
ATOM 2881 C "C2'" . C   C 3 11  ? 125.296 131.484 113.024 1.00 34.64  ? -15 C   B "C2'" 1 
ATOM 2882 O "O2'" . C   C 3 11  ? 125.589 132.279 114.163 1.00 34.64  ? -15 C   B "O2'" 1 
ATOM 2883 C "C1'" . C   C 3 11  ? 125.802 130.066 113.283 1.00 34.64  ? -15 C   B "C1'" 1 
ATOM 2884 N N1    . C   C 3 11  ? 126.149 129.360 112.032 1.00 34.64  ? -15 C   B N1    1 
ATOM 2885 C C2    . C   C 3 11  ? 127.163 129.817 111.180 1.00 34.64  ? -15 C   B C2    1 
ATOM 2886 O O2    . C   C 3 11  ? 127.791 130.848 111.469 1.00 34.64  ? -15 C   B O2    1 
ATOM 2887 N N3    . C   C 3 11  ? 127.417 129.127 110.047 1.00 34.64  ? -15 C   B N3    1 
ATOM 2888 C C4    . C   C 3 11  ? 126.724 128.026 109.761 1.00 34.64  ? -15 C   B C4    1 
ATOM 2889 N N4    . C   C 3 11  ? 127.003 127.364 108.638 1.00 34.64  ? -15 C   B N4    1 
ATOM 2890 C C5    . C   C 3 11  ? 125.697 127.538 110.608 1.00 34.64  ? -15 C   B C5    1 
ATOM 2891 C C6    . C   C 3 11  ? 125.451 128.230 111.719 1.00 34.64  ? -15 C   B C6    1 
ATOM 2892 P P     . U   C 3 12  ? 122.533 133.318 111.893 1.00 39.28  ? -14 U   B P     1 
ATOM 2893 O OP1   . U   C 3 12  ? 121.687 134.408 112.438 1.00 39.28  ? -14 U   B OP1   1 
ATOM 2894 O OP2   . U   C 3 12  ? 121.971 132.432 110.843 1.00 39.28  ? -14 U   B OP2   1 
ATOM 2895 O "O5'" . U   C 3 12  ? 123.874 133.980 111.356 1.00 39.28  ? -14 U   B "O5'" 1 
ATOM 2896 C "C5'" . U   C 3 12  ? 124.635 134.840 112.186 1.00 39.28  ? -14 U   B "C5'" 1 
ATOM 2897 C "C4'" . U   C 3 12  ? 125.772 135.480 111.432 1.00 39.28  ? -14 U   B "C4'" 1 
ATOM 2898 O "O4'" . U   C 3 12  ? 126.777 134.486 111.106 1.00 39.28  ? -14 U   B "O4'" 1 
ATOM 2899 C "C3'" . U   C 3 12  ? 125.417 136.103 110.092 1.00 39.28  ? -14 U   B "C3'" 1 
ATOM 2900 O "O3'" . U   C 3 12  ? 124.842 137.393 110.227 1.00 39.28  ? -14 U   B "O3'" 1 
ATOM 2901 C "C2'" . U   C 3 12  ? 126.755 136.097 109.360 1.00 39.28  ? -14 U   B "C2'" 1 
ATOM 2902 O "O2'" . U   C 3 12  ? 127.572 137.172 109.798 1.00 39.28  ? -14 U   B "O2'" 1 
ATOM 2903 C "C1'" . U   C 3 12  ? 127.372 134.792 109.862 1.00 39.28  ? -14 U   B "C1'" 1 
ATOM 2904 N N1    . U   C 3 12  ? 127.139 133.658 108.939 1.00 39.28  ? -14 U   B N1    1 
ATOM 2905 C C2    . U   C 3 12  ? 127.846 133.615 107.756 1.00 39.28  ? -14 U   B C2    1 
ATOM 2906 O O2    . U   C 3 12  ? 128.647 134.472 107.425 1.00 39.28  ? -14 U   B O2    1 
ATOM 2907 N N3    . U   C 3 12  ? 127.577 132.526 106.961 1.00 39.28  ? -14 U   B N3    1 
ATOM 2908 C C4    . U   C 3 12  ? 126.693 131.499 107.231 1.00 39.28  ? -14 U   B C4    1 
ATOM 2909 O O4    . U   C 3 12  ? 126.549 130.578 106.427 1.00 39.28  ? -14 U   B O4    1 
ATOM 2910 C C5    . U   C 3 12  ? 126.006 131.617 108.471 1.00 39.28  ? -14 U   B C5    1 
ATOM 2911 C C6    . U   C 3 12  ? 126.250 132.660 109.261 1.00 39.28  ? -14 U   B C6    1 
ATOM 2912 P P     . C   C 3 13  ? 123.782 137.943 109.149 1.00 41.19  ? -13 C   B P     1 
ATOM 2913 O OP1   . C   C 3 13  ? 123.434 139.330 109.545 1.00 41.19  ? -13 C   B OP1   1 
ATOM 2914 O OP2   . C   C 3 13  ? 122.689 136.956 108.967 1.00 41.19  ? -13 C   B OP2   1 
ATOM 2915 O "O5'" . C   C 3 13  ? 124.623 138.035 107.803 1.00 41.19  ? -13 C   B "O5'" 1 
ATOM 2916 C "C5'" . C   C 3 13  ? 125.671 138.983 107.673 1.00 41.19  ? -13 C   B "C5'" 1 
ATOM 2917 C "C4'" . C   C 3 13  ? 126.396 138.845 106.358 1.00 41.19  ? -13 C   B "C4'" 1 
ATOM 2918 O "O4'" . C   C 3 13  ? 127.058 137.559 106.281 1.00 41.19  ? -13 C   B "O4'" 1 
ATOM 2919 C "C3'" . C   C 3 13  ? 125.537 138.886 105.107 1.00 41.19  ? -13 C   B "C3'" 1 
ATOM 2920 O "O3'" . C   C 3 13  ? 125.169 140.202 104.740 1.00 41.19  ? -13 C   B "O3'" 1 
ATOM 2921 C "C2'" . C   C 3 13  ? 126.421 138.195 104.079 1.00 41.19  ? -13 C   B "C2'" 1 
ATOM 2922 O "O2'" . C   C 3 13  ? 127.411 139.087 103.588 1.00 41.19  ? -13 C   B "O2'" 1 
ATOM 2923 C "C1'" . C   C 3 13  ? 127.112 137.131 104.936 1.00 41.19  ? -13 C   B "C1'" 1 
ATOM 2924 N N1    . C   C 3 13  ? 126.461 135.807 104.816 1.00 41.19  ? -13 C   B N1    1 
ATOM 2925 C C2    . C   C 3 13  ? 126.765 135.040 103.692 1.00 41.19  ? -13 C   B C2    1 
ATOM 2926 O O2    . C   C 3 13  ? 127.555 135.522 102.867 1.00 41.19  ? -13 C   B O2    1 
ATOM 2927 N N3    . C   C 3 13  ? 126.197 133.827 103.534 1.00 41.19  ? -13 C   B N3    1 
ATOM 2928 C C4    . C   C 3 13  ? 125.352 133.379 104.463 1.00 41.19  ? -13 C   B C4    1 
ATOM 2929 N N4    . C   C 3 13  ? 124.805 132.176 104.284 1.00 41.19  ? -13 C   B N4    1 
ATOM 2930 C C5    . C   C 3 13  ? 125.025 134.137 105.623 1.00 41.19  ? -13 C   B C5    1 
ATOM 2931 C C6    . C   C 3 13  ? 125.596 135.338 105.761 1.00 41.19  ? -13 C   B C6    1 
ATOM 2932 P P     . G   C 3 14  ? 124.080 140.444 103.589 1.00 39.98  ? -12 G   B P     1 
ATOM 2933 O OP1   . G   C 3 14  ? 123.516 141.800 103.790 1.00 39.98  ? -12 G   B OP1   1 
ATOM 2934 O OP2   . G   C 3 14  ? 123.175 139.270 103.552 1.00 39.98  ? -12 G   B OP2   1 
ATOM 2935 O "O5'" . G   C 3 14  ? 124.936 140.445 102.246 1.00 39.98  ? -12 G   B "O5'" 1 
ATOM 2936 C "C5'" . G   C 3 14  ? 124.329 140.167 100.994 1.00 39.98  ? -12 G   B "C5'" 1 
ATOM 2937 C "C4'" . G   C 3 14  ? 125.294 139.494 100.050 1.00 39.98  ? -12 G   B "C4'" 1 
ATOM 2938 O "O4'" . G   C 3 14  ? 125.985 138.420 100.738 1.00 39.98  ? -12 G   B "O4'" 1 
ATOM 2939 C "C3'" . G   C 3 14  ? 124.670 138.817 98.840  1.00 39.98  ? -12 G   B "C3'" 1 
ATOM 2940 O "O3'" . G   C 3 14  ? 124.385 139.716 97.788  1.00 39.98  ? -12 G   B "O3'" 1 
ATOM 2941 C "C2'" . G   C 3 14  ? 125.705 137.768 98.476  1.00 39.98  ? -12 G   B "C2'" 1 
ATOM 2942 O "O2'" . G   C 3 14  ? 126.794 138.359 97.782  1.00 39.98  ? -12 G   B "O2'" 1 
ATOM 2943 C "C1'" . G   C 3 14  ? 126.189 137.336 99.858  1.00 39.98  ? -12 G   B "C1'" 1 
ATOM 2944 N N9    . G   C 3 14  ? 125.438 136.178 100.373 1.00 39.98  ? -12 G   B N9    1 
ATOM 2945 C C8    . G   C 3 14  ? 124.737 136.122 101.549 1.00 39.98  ? -12 G   B C8    1 
ATOM 2946 N N7    . G   C 3 14  ? 124.173 134.965 101.757 1.00 39.98  ? -12 G   B N7    1 
ATOM 2947 C C5    . G   C 3 14  ? 124.523 134.211 100.648 1.00 39.98  ? -12 G   B C5    1 
ATOM 2948 C C6    . G   C 3 14  ? 124.200 132.874 100.307 1.00 39.98  ? -12 G   B C6    1 
ATOM 2949 O O6    . G   C 3 14  ? 123.523 132.056 100.942 1.00 39.98  ? -12 G   B O6    1 
ATOM 2950 N N1    . G   C 3 14  ? 124.762 132.508 99.092  1.00 39.98  ? -12 G   B N1    1 
ATOM 2951 C C2    . G   C 3 14  ? 125.531 133.319 98.303  1.00 39.98  ? -12 G   B C2    1 
ATOM 2952 N N2    . G   C 3 14  ? 125.993 132.801 97.158  1.00 39.98  ? -12 G   B N2    1 
ATOM 2953 N N3    . G   C 3 14  ? 125.838 134.564 98.611  1.00 39.98  ? -12 G   B N3    1 
ATOM 2954 C C4    . G   C 3 14  ? 125.308 134.943 99.788  1.00 39.98  ? -12 G   B C4    1 
ATOM 2955 P P     . G   C 3 15  ? 122.959 139.655 97.060  1.00 40.53  ? -11 G   B P     1 
ATOM 2956 O OP1   . G   C 3 15  ? 122.702 140.966 96.411  1.00 40.53  ? -11 G   B OP1   1 
ATOM 2957 O OP2   . G   C 3 15  ? 121.991 139.120 98.051  1.00 40.53  ? -11 G   B OP2   1 
ATOM 2958 O "O5'" . G   C 3 15  ? 123.164 138.566 95.918  1.00 40.53  ? -11 G   B "O5'" 1 
ATOM 2959 C "C5'" . G   C 3 15  ? 124.099 138.773 94.872  1.00 40.53  ? -11 G   B "C5'" 1 
ATOM 2960 C "C4'" . G   C 3 15  ? 124.111 137.611 93.914  1.00 40.53  ? -11 G   B "C4'" 1 
ATOM 2961 O "O4'" . G   C 3 15  ? 124.649 136.440 94.580  1.00 40.53  ? -11 G   B "O4'" 1 
ATOM 2962 C "C3'" . G   C 3 15  ? 122.748 137.169 93.408  1.00 40.53  ? -11 G   B "C3'" 1 
ATOM 2963 O "O3'" . G   C 3 15  ? 122.306 137.940 92.302  1.00 40.53  ? -11 G   B "O3'" 1 
ATOM 2964 C "C2'" . G   C 3 15  ? 122.967 135.697 93.079  1.00 40.53  ? -11 G   B "C2'" 1 
ATOM 2965 O "O2'" . G   C 3 15  ? 123.596 135.553 91.813  1.00 40.53  ? -11 G   B "O2'" 1 
ATOM 2966 C "C1'" . G   C 3 15  ? 123.964 135.283 94.163  1.00 40.53  ? -11 G   B "C1'" 1 
ATOM 2967 N N9    . G   C 3 15  ? 123.308 134.684 95.340  1.00 40.53  ? -11 G   B N9    1 
ATOM 2968 C C8    . G   C 3 15  ? 123.027 135.316 96.523  1.00 40.53  ? -11 G   B C8    1 
ATOM 2969 N N7    . G   C 3 15  ? 122.445 134.541 97.395  1.00 40.53  ? -11 G   B N7    1 
ATOM 2970 C C5    . G   C 3 15  ? 122.338 133.323 96.752  1.00 40.53  ? -11 G   B C5    1 
ATOM 2971 C C6    . G   C 3 15  ? 121.787 132.102 97.205  1.00 40.53  ? -11 G   B C6    1 
ATOM 2972 O O6    . G   C 3 15  ? 121.273 131.845 98.300  1.00 40.53  ? -11 G   B O6    1 
ATOM 2973 N N1    . G   C 3 15  ? 121.877 131.114 96.232  1.00 40.53  ? -11 G   B N1    1 
ATOM 2974 C C2    . G   C 3 15  ? 122.426 131.289 94.988  1.00 40.53  ? -11 G   B C2    1 
ATOM 2975 N N2    . G   C 3 15  ? 122.421 130.205 94.201  1.00 40.53  ? -11 G   B N2    1 
ATOM 2976 N N3    . G   C 3 15  ? 122.943 132.422 94.558  1.00 40.53  ? -11 G   B N3    1 
ATOM 2977 C C4    . G   C 3 15  ? 122.867 133.392 95.487  1.00 40.53  ? -11 G   B C4    1 
ATOM 2978 P P     . U   C 3 16  ? 120.770 138.398 92.181  1.00 40.20  ? -10 U   B P     1 
ATOM 2979 O OP1   . U   C 3 16  ? 120.661 139.299 91.009  1.00 40.20  ? -10 U   B OP1   1 
ATOM 2980 O OP2   . U   C 3 16  ? 120.316 138.872 93.511  1.00 40.20  ? -10 U   B OP2   1 
ATOM 2981 O "O5'" . U   C 3 16  ? 119.984 137.056 91.838  1.00 40.20  ? -10 U   B "O5'" 1 
ATOM 2982 C "C5'" . U   C 3 16  ? 120.085 136.452 90.556  1.00 40.20  ? -10 U   B "C5'" 1 
ATOM 2983 C "C4'" . U   C 3 16  ? 119.396 135.111 90.523  1.00 40.20  ? -10 U   B "C4'" 1 
ATOM 2984 O "O4'" . U   C 3 16  ? 119.964 134.251 91.538  1.00 40.20  ? -10 U   B "O4'" 1 
ATOM 2985 C "C3'" . U   C 3 16  ? 117.904 135.123 90.822  1.00 40.20  ? -10 U   B "C3'" 1 
ATOM 2986 O "O3'" . U   C 3 16  ? 117.141 135.420 89.665  1.00 40.20  ? -10 U   B "O3'" 1 
ATOM 2987 C "C2'" . U   C 3 16  ? 117.646 133.729 91.382  1.00 40.20  ? -10 U   B "C2'" 1 
ATOM 2988 O "O2'" . U   C 3 16  ? 117.457 132.796 90.332  1.00 40.20  ? -10 U   B "O2'" 1 
ATOM 2989 C "C1'" . U   C 3 16  ? 118.970 133.416 92.083  1.00 40.20  ? -10 U   B "C1'" 1 
ATOM 2990 N N1    . U   C 3 16  ? 118.930 133.640 93.544  1.00 40.20  ? -10 U   B N1    1 
ATOM 2991 C C2    . U   C 3 16  ? 118.534 132.593 94.350  1.00 40.20  ? -10 U   B C2    1 
ATOM 2992 O O2    . U   C 3 16  ? 118.193 131.510 93.908  1.00 40.20  ? -10 U   B O2    1 
ATOM 2993 N N3    . U   C 3 16  ? 118.537 132.866 95.695  1.00 40.20  ? -10 U   B N3    1 
ATOM 2994 C C4    . U   C 3 16  ? 118.904 134.047 96.297  1.00 40.20  ? -10 U   B C4    1 
ATOM 2995 O O4    . U   C 3 16  ? 118.856 134.149 97.520  1.00 40.20  ? -10 U   B O4    1 
ATOM 2996 C C5    . U   C 3 16  ? 119.312 135.070 95.393  1.00 40.20  ? -10 U   B C5    1 
ATOM 2997 C C6    . U   C 3 16  ? 119.314 134.838 94.082  1.00 40.20  ? -10 U   B C6    1 
ATOM 2998 P P     . U   C 3 17  ? 115.535 135.398 89.700  1.00 38.07  ? -9  U   B P     1 
ATOM 2999 O OP1   . U   C 3 17  ? 115.054 136.324 88.645  1.00 38.07  ? -9  U   B OP1   1 
ATOM 3000 O OP2   . U   C 3 17  ? 115.085 135.605 91.099  1.00 38.07  ? -9  U   B OP2   1 
ATOM 3001 O "O5'" . U   C 3 17  ? 115.155 133.921 89.245  1.00 38.07  ? -9  U   B "O5'" 1 
ATOM 3002 C "C5'" . U   C 3 17  ? 113.890 133.653 88.648  1.00 38.07  ? -9  U   B "C5'" 1 
ATOM 3003 C "C4'" . U   C 3 17  ? 113.868 132.345 87.888  1.00 38.07  ? -9  U   B "C4'" 1 
ATOM 3004 O "O4'" . U   C 3 17  ? 114.875 132.365 86.836  1.00 38.07  ? -9  U   B "O4'" 1 
ATOM 3005 C "C3'" . U   C 3 17  ? 114.137 131.085 88.714  1.00 38.07  ? -9  U   B "C3'" 1 
ATOM 3006 O "O3'" . U   C 3 17  ? 113.311 130.023 88.245  1.00 38.07  ? -9  U   B "O3'" 1 
ATOM 3007 C "C2'" . U   C 3 17  ? 115.594 130.769 88.387  1.00 38.07  ? -9  U   B "C2'" 1 
ATOM 3008 O "O2'" . U   C 3 17  ? 115.953 129.413 88.550  1.00 38.07  ? -9  U   B "O2'" 1 
ATOM 3009 C "C1'" . U   C 3 17  ? 115.675 131.205 86.930  1.00 38.07  ? -9  U   B "C1'" 1 
ATOM 3010 N N1    . U   C 3 17  ? 117.028 131.508 86.439  1.00 38.07  ? -9  U   B N1    1 
ATOM 3011 C C2    . U   C 3 17  ? 117.782 132.516 87.013  1.00 38.07  ? -9  U   B C2    1 
ATOM 3012 O O2    . U   C 3 17  ? 117.401 133.205 87.941  1.00 38.07  ? -9  U   B O2    1 
ATOM 3013 N N3    . U   C 3 17  ? 119.027 132.704 86.461  1.00 38.07  ? -9  U   B N3    1 
ATOM 3014 C C4    . U   C 3 17  ? 119.591 132.007 85.416  1.00 38.07  ? -9  U   B C4    1 
ATOM 3015 O O4    . U   C 3 17  ? 120.724 132.293 85.037  1.00 38.07  ? -9  U   B O4    1 
ATOM 3016 C C5    . U   C 3 17  ? 118.747 130.988 84.875  1.00 38.07  ? -9  U   B C5    1 
ATOM 3017 C C6    . U   C 3 17  ? 117.531 130.783 85.391  1.00 38.07  ? -9  U   B C6    1 
ATOM 3018 P P     . C   C 3 18  ? 111.878 129.750 88.918  1.00 39.51  ? -8  C   B P     1 
ATOM 3019 O OP1   . C   C 3 18  ? 111.326 128.504 88.335  1.00 39.51  ? -8  C   B OP1   1 
ATOM 3020 O OP2   . C   C 3 18  ? 111.088 131.004 88.857  1.00 39.51  ? -8  C   B OP2   1 
ATOM 3021 O "O5'" . C   C 3 18  ? 112.217 129.441 90.441  1.00 39.51  ? -8  C   B "O5'" 1 
ATOM 3022 C "C5'" . C   C 3 18  ? 112.787 128.194 90.814  1.00 39.51  ? -8  C   B "C5'" 1 
ATOM 3023 C "C4'" . C   C 3 18  ? 112.963 128.073 92.307  1.00 39.51  ? -8  C   B "C4'" 1 
ATOM 3024 O "O4'" . C   C 3 18  ? 113.987 129.003 92.755  1.00 39.51  ? -8  C   B "O4'" 1 
ATOM 3025 C "C3'" . C   C 3 18  ? 111.719 128.369 93.148  1.00 39.51  ? -8  C   B "C3'" 1 
ATOM 3026 O "O3'" . C   C 3 18  ? 111.700 127.507 94.286  1.00 39.51  ? -8  C   B "O3'" 1 
ATOM 3027 C "C2'" . C   C 3 18  ? 111.971 129.794 93.621  1.00 39.51  ? -8  C   B "C2'" 1 
ATOM 3028 O "O2'" . C   C 3 18  ? 111.287 130.150 94.803  1.00 39.51  ? -8  C   B "O2'" 1 
ATOM 3029 C "C1'" . C   C 3 18  ? 113.480 129.770 93.824  1.00 39.51  ? -8  C   B "C1'" 1 
ATOM 3030 N N1    . C   C 3 18  ? 114.117 131.093 93.822  1.00 39.51  ? -8  C   B N1    1 
ATOM 3031 C C2    . C   C 3 18  ? 114.977 131.400 94.878  1.00 39.51  ? -8  C   B C2    1 
ATOM 3032 O O2    . C   C 3 18  ? 115.179 130.546 95.753  1.00 39.51  ? -8  C   B O2    1 
ATOM 3033 N N3    . C   C 3 18  ? 115.569 132.607 94.924  1.00 39.51  ? -8  C   B N3    1 
ATOM 3034 C C4    . C   C 3 18  ? 115.325 133.492 93.964  1.00 39.51  ? -8  C   B C4    1 
ATOM 3035 N N4    . C   C 3 18  ? 115.933 134.678 94.044  1.00 39.51  ? -8  C   B N4    1 
ATOM 3036 C C5    . C   C 3 18  ? 114.446 133.208 92.881  1.00 39.51  ? -8  C   B C5    1 
ATOM 3037 C C6    . C   C 3 18  ? 113.862 132.007 92.850  1.00 39.51  ? -8  C   B C6    1 
ATOM 3038 P P     . G   C 3 19  ? 111.398 125.938 94.122  1.00 38.95  ? -7  G   B P     1 
ATOM 3039 O OP1   . G   C 3 19  ? 110.691 125.727 92.833  1.00 38.95  ? -7  G   B OP1   1 
ATOM 3040 O OP2   . G   C 3 19  ? 110.771 125.464 95.381  1.00 38.95  ? -7  G   B OP2   1 
ATOM 3041 O "O5'" . G   C 3 19  ? 112.845 125.280 94.010  1.00 38.95  ? -7  G   B "O5'" 1 
ATOM 3042 C "C5'" . G   C 3 19  ? 113.083 123.965 94.486  1.00 38.95  ? -7  G   B "C5'" 1 
ATOM 3043 C "C4'" . G   C 3 19  ? 114.232 123.302 93.767  1.00 38.95  ? -7  G   B "C4'" 1 
ATOM 3044 O "O4'" . G   C 3 19  ? 114.457 123.938 92.483  1.00 38.95  ? -7  G   B "O4'" 1 
ATOM 3045 C "C3'" . G   C 3 19  ? 115.593 123.379 94.434  1.00 38.95  ? -7  G   B "C3'" 1 
ATOM 3046 O "O3'" . G   C 3 19  ? 115.754 122.504 95.535  1.00 38.95  ? -7  G   B "O3'" 1 
ATOM 3047 C "C2'" . G   C 3 19  ? 116.536 123.094 93.276  1.00 38.95  ? -7  G   B "C2'" 1 
ATOM 3048 O "O2'" . G   C 3 19  ? 116.571 121.703 92.989  1.00 38.95  ? -7  G   B "O2'" 1 
ATOM 3049 C "C1'" . G   C 3 19  ? 115.821 123.806 92.126  1.00 38.95  ? -7  G   B "C1'" 1 
ATOM 3050 N N9    . G   C 3 19  ? 116.412 125.129 91.837  1.00 38.95  ? -7  G   B N9    1 
ATOM 3051 C C8    . G   C 3 19  ? 117.002 125.459 90.645  1.00 38.95  ? -7  G   B C8    1 
ATOM 3052 N N7    . G   C 3 19  ? 117.472 126.669 90.613  1.00 38.95  ? -7  G   B N7    1 
ATOM 3053 C C5    . G   C 3 19  ? 117.188 127.177 91.866  1.00 38.95  ? -7  G   B C5    1 
ATOM 3054 C C6    . G   C 3 19  ? 117.462 128.453 92.401  1.00 38.95  ? -7  G   B C6    1 
ATOM 3055 O O6    . G   C 3 19  ? 118.030 129.407 91.855  1.00 38.95  ? -7  G   B O6    1 
ATOM 3056 N N1    . G   C 3 19  ? 117.009 128.574 93.704  1.00 38.95  ? -7  G   B N1    1 
ATOM 3057 C C2    . G   C 3 19  ? 116.370 127.587 94.403  1.00 38.95  ? -7  G   B C2    1 
ATOM 3058 N N2    . G   C 3 19  ? 116.005 127.889 95.657  1.00 38.95  ? -7  G   B N2    1 
ATOM 3059 N N3    . G   C 3 19  ? 116.105 126.391 93.910  1.00 38.95  ? -7  G   B N3    1 
ATOM 3060 C C4    . G   C 3 19  ? 116.540 126.246 92.641  1.00 38.95  ? -7  G   B C4    1 
ATOM 3061 P P     . C   C 3 20  ? 116.612 122.993 96.800  1.00 34.42  ? -6  C   B P     1 
ATOM 3062 O OP1   . C   C 3 20  ? 116.892 121.835 97.675  1.00 34.42  ? -6  C   B OP1   1 
ATOM 3063 O OP2   . C   C 3 20  ? 115.965 124.207 97.357  1.00 34.42  ? -6  C   B OP2   1 
ATOM 3064 O "O5'" . C   C 3 20  ? 118.008 123.418 96.176  1.00 34.42  ? -6  C   B "O5'" 1 
ATOM 3065 C "C5'" . C   C 3 20  ? 118.939 122.433 95.759  1.00 34.42  ? -6  C   B "C5'" 1 
ATOM 3066 C "C4'" . C   C 3 20  ? 120.216 123.052 95.269  1.00 34.42  ? -6  C   B "C4'" 1 
ATOM 3067 O "O4'" . C   C 3 20  ? 120.017 124.483 95.101  1.00 34.42  ? -6  C   B "O4'" 1 
ATOM 3068 C "C3'" . C   C 3 20  ? 121.411 122.900 96.206  1.00 34.42  ? -6  C   B "C3'" 1 
ATOM 3069 O "O3'" . C   C 3 20  ? 122.594 122.838 95.408  1.00 34.42  ? -6  C   B "O3'" 1 
ATOM 3070 C "C2'" . C   C 3 20  ? 121.370 124.207 96.989  1.00 34.42  ? -6  C   B "C2'" 1 
ATOM 3071 O "O2'" . C   C 3 20  ? 122.577 124.585 97.614  1.00 34.42  ? -6  C   B "O2'" 1 
ATOM 3072 C "C1'" . C   C 3 20  ? 120.949 125.188 95.903  1.00 34.42  ? -6  C   B "C1'" 1 
ATOM 3073 N N1    . C   C 3 20  ? 120.313 126.404 96.431  1.00 34.42  ? -6  C   B N1    1 
ATOM 3074 C C2    . C   C 3 20  ? 120.782 127.649 96.022  1.00 34.42  ? -6  C   B C2    1 
ATOM 3075 O O2    . C   C 3 20  ? 121.699 127.730 95.198  1.00 34.42  ? -6  C   B O2    1 
ATOM 3076 N N3    . C   C 3 20  ? 120.221 128.766 96.520  1.00 34.42  ? -6  C   B N3    1 
ATOM 3077 C C4    . C   C 3 20  ? 119.226 128.672 97.403  1.00 34.42  ? -6  C   B C4    1 
ATOM 3078 N N4    . C   C 3 20  ? 118.694 129.804 97.869  1.00 34.42  ? -6  C   B N4    1 
ATOM 3079 C C5    . C   C 3 20  ? 118.733 127.417 97.853  1.00 34.42  ? -6  C   B C5    1 
ATOM 3080 C C6    . C   C 3 20  ? 119.306 126.319 97.349  1.00 34.42  ? -6  C   B C6    1 
ATOM 3081 P P     . C   C 3 21  ? 124.046 122.608 96.057  1.00 35.17  ? -5  C   B P     1 
ATOM 3082 O OP1   . C   C 3 21  ? 124.718 121.495 95.342  1.00 35.17  ? -5  C   B OP1   1 
ATOM 3083 O OP2   . C   C 3 21  ? 123.917 122.543 97.534  1.00 35.17  ? -5  C   B OP2   1 
ATOM 3084 O "O5'" . C   C 3 21  ? 124.808 123.949 95.673  1.00 35.17  ? -5  C   B "O5'" 1 
ATOM 3085 C "C5'" . C   C 3 21  ? 124.754 124.432 94.344  1.00 35.17  ? -5  C   B "C5'" 1 
ATOM 3086 C "C4'" . C   C 3 21  ? 125.342 125.812 94.210  1.00 35.17  ? -5  C   B "C4'" 1 
ATOM 3087 O "O4'" . C   C 3 21  ? 124.354 126.817 94.550  1.00 35.17  ? -5  C   B "O4'" 1 
ATOM 3088 C "C3'" . C   C 3 21  ? 126.520 126.154 95.101  1.00 35.17  ? -5  C   B "C3'" 1 
ATOM 3089 O "O3'" . C   C 3 21  ? 127.742 125.613 94.654  1.00 35.17  ? -5  C   B "O3'" 1 
ATOM 3090 C "C2'" . C   C 3 21  ? 126.505 127.672 95.079  1.00 35.17  ? -5  C   B "C2'" 1 
ATOM 3091 O "O2'" . C   C 3 21  ? 127.066 128.158 93.870  1.00 35.17  ? -5  C   B "O2'" 1 
ATOM 3092 C "C1'" . C   C 3 21  ? 125.004 127.959 95.070  1.00 35.17  ? -5  C   B "C1'" 1 
ATOM 3093 N N1    . C   C 3 21  ? 124.500 128.236 96.433  1.00 35.17  ? -5  C   B N1    1 
ATOM 3094 C C2    . C   C 3 21  ? 124.669 129.526 96.924  1.00 35.17  ? -5  C   B C2    1 
ATOM 3095 O O2    . C   C 3 21  ? 125.215 130.361 96.193  1.00 35.17  ? -5  C   B O2    1 
ATOM 3096 N N3    . C   C 3 21  ? 124.235 129.826 98.163  1.00 35.17  ? -5  C   B N3    1 
ATOM 3097 C C4    . C   C 3 21  ? 123.659 128.889 98.908  1.00 35.17  ? -5  C   B C4    1 
ATOM 3098 N N4    . C   C 3 21  ? 123.242 129.228 100.128 1.00 35.17  ? -5  C   B N4    1 
ATOM 3099 C C5    . C   C 3 21  ? 123.475 127.564 98.434  1.00 35.17  ? -5  C   B C5    1 
ATOM 3100 C C6    . C   C 3 21  ? 123.913 127.277 97.204  1.00 35.17  ? -5  C   B C6    1 
ATOM 3101 P P     . G   C 3 22  ? 128.954 125.425 95.685  1.00 37.88  ? -4  G   B P     1 
ATOM 3102 O OP1   . G   C 3 22  ? 130.053 124.723 94.971  1.00 37.88  ? -4  G   B OP1   1 
ATOM 3103 O OP2   . G   C 3 22  ? 128.382 124.837 96.921  1.00 37.88  ? -4  G   B OP2   1 
ATOM 3104 O "O5'" . G   C 3 22  ? 129.426 126.912 96.017  1.00 37.88  ? -4  G   B "O5'" 1 
ATOM 3105 C "C5'" . G   C 3 22  ? 130.011 127.734 95.017  1.00 37.88  ? -4  G   B "C5'" 1 
ATOM 3106 C "C4'" . G   C 3 22  ? 130.163 129.164 95.475  1.00 37.88  ? -4  G   B "C4'" 1 
ATOM 3107 O "O4'" . G   C 3 22  ? 128.872 129.733 95.801  1.00 37.88  ? -4  G   B "O4'" 1 
ATOM 3108 C "C3'" . G   C 3 22  ? 130.983 129.391 96.729  1.00 37.88  ? -4  G   B "C3'" 1 
ATOM 3109 O "O3'" . G   C 3 22  ? 132.375 129.342 96.486  1.00 37.88  ? -4  G   B "O3'" 1 
ATOM 3110 C "C2'" . G   C 3 22  ? 130.501 130.759 97.190  1.00 37.88  ? -4  G   B "C2'" 1 
ATOM 3111 O "O2'" . G   C 3 22  ? 131.111 131.787 96.426  1.00 37.88  ? -4  G   B "O2'" 1 
ATOM 3112 C "C1'" . G   C 3 22  ? 129.023 130.704 96.815  1.00 37.88  ? -4  G   B "C1'" 1 
ATOM 3113 N N9    . G   C 3 22  ? 128.168 130.352 97.962  1.00 37.88  ? -4  G   B N9    1 
ATOM 3114 C C8    . G   C 3 22  ? 127.437 129.207 98.147  1.00 37.88  ? -4  G   B C8    1 
ATOM 3115 N N7    . G   C 3 22  ? 126.776 129.200 99.273  1.00 37.88  ? -4  G   B N7    1 
ATOM 3116 C C5    . G   C 3 22  ? 127.091 130.414 99.866  1.00 37.88  ? -4  G   B C5    1 
ATOM 3117 C C6    . G   C 3 22  ? 126.679 130.973 101.103 1.00 37.88  ? -4  G   B C6    1 
ATOM 3118 O O6    . G   C 3 22  ? 125.920 130.493 101.952 1.00 37.88  ? -4  G   B O6    1 
ATOM 3119 N N1    . G   C 3 22  ? 127.241 132.224 101.309 1.00 37.88  ? -4  G   B N1    1 
ATOM 3120 C C2    . G   C 3 22  ? 128.091 132.849 100.437 1.00 37.88  ? -4  G   B C2    1 
ATOM 3121 N N2    . G   C 3 22  ? 128.554 134.055 100.790 1.00 37.88  ? -4  G   B N2    1 
ATOM 3122 N N3    . G   C 3 22  ? 128.482 132.341 99.290  1.00 37.88  ? -4  G   B N3    1 
ATOM 3123 C C4    . G   C 3 22  ? 127.948 131.132 99.068  1.00 37.88  ? -4  G   B C4    1 
ATOM 3124 P P     . A   C 3 23  ? 133.373 128.869 97.649  1.00 38.46  ? -3  A   B P     1 
ATOM 3125 O OP1   . A   C 3 23  ? 134.700 128.607 97.042  1.00 38.46  ? -3  A   B OP1   1 
ATOM 3126 O OP2   . A   C 3 23  ? 132.683 127.800 98.415  1.00 38.46  ? -3  A   B OP2   1 
ATOM 3127 O "O5'" . A   C 3 23  ? 133.505 130.150 98.583  1.00 38.46  ? -3  A   B "O5'" 1 
ATOM 3128 C "C5'" . A   C 3 23  ? 133.965 131.386 98.057  1.00 38.46  ? -3  A   B "C5'" 1 
ATOM 3129 C "C4'" . A   C 3 23  ? 133.872 132.485 99.083  1.00 38.46  ? -3  A   B "C4'" 1 
ATOM 3130 O "O4'" . A   C 3 23  ? 132.483 132.832 99.314  1.00 38.46  ? -3  A   B "O4'" 1 
ATOM 3131 C "C3'" . A   C 3 23  ? 134.400 132.144 100.464 1.00 38.46  ? -3  A   B "C3'" 1 
ATOM 3132 O "O3'" . A   C 3 23  ? 135.809 132.242 100.551 1.00 38.46  ? -3  A   B "O3'" 1 
ATOM 3133 C "C2'" . A   C 3 23  ? 133.659 133.132 101.355 1.00 38.46  ? -3  A   B "C2'" 1 
ATOM 3134 O "O2'" . A   C 3 23  ? 134.262 134.415 101.289 1.00 38.46  ? -3  A   B "O2'" 1 
ATOM 3135 C "C1'" . A   C 3 23  ? 132.300 133.203 100.664 1.00 38.46  ? -3  A   B "C1'" 1 
ATOM 3136 N N9    . A   C 3 23  ? 131.316 132.292 101.267 1.00 38.46  ? -3  A   B N9    1 
ATOM 3137 C C8    . A   C 3 23  ? 130.810 131.141 100.730 1.00 38.46  ? -3  A   B C8    1 
ATOM 3138 N N7    . A   C 3 23  ? 129.932 130.541 101.490 1.00 38.46  ? -3  A   B N7    1 
ATOM 3139 C C5    . A   C 3 23  ? 129.864 131.352 102.607 1.00 38.46  ? -3  A   B C5    1 
ATOM 3140 C C6    . A   C 3 23  ? 129.113 131.261 103.781 1.00 38.46  ? -3  A   B C6    1 
ATOM 3141 N N6    . A   C 3 23  ? 128.264 130.268 104.032 1.00 38.46  ? -3  A   B N6    1 
ATOM 3142 N N1    . A   C 3 23  ? 129.268 132.232 104.702 1.00 38.46  ? -3  A   B N1    1 
ATOM 3143 C C2    . A   C 3 23  ? 130.125 133.229 104.444 1.00 38.46  ? -3  A   B C2    1 
ATOM 3144 N N3    . A   C 3 23  ? 130.889 133.425 103.372 1.00 38.46  ? -3  A   B N3    1 
ATOM 3145 C C4    . A   C 3 23  ? 130.706 132.438 102.482 1.00 38.46  ? -3  A   B C4    1 
ATOM 3146 P P     . G   C 3 24  ? 136.618 131.296 101.563 1.00 37.34  ? -2  G   B P     1 
ATOM 3147 O OP1   . G   C 3 24  ? 137.864 131.998 101.960 1.00 37.34  ? -2  G   B OP1   1 
ATOM 3148 O OP2   . G   C 3 24  ? 136.696 129.940 100.970 1.00 37.34  ? -2  G   B OP2   1 
ATOM 3149 O "O5'" . G   C 3 24  ? 135.671 131.216 102.837 1.00 37.34  ? -2  G   B "O5'" 1 
ATOM 3150 C "C5'" . G   C 3 24  ? 136.212 131.152 104.146 1.00 37.34  ? -2  G   B "C5'" 1 
ATOM 3151 C "C4'" . G   C 3 24  ? 135.533 132.131 105.070 1.00 37.34  ? -2  G   B "C4'" 1 
ATOM 3152 O "O4'" . G   C 3 24  ? 134.126 132.223 104.742 1.00 37.34  ? -2  G   B "O4'" 1 
ATOM 3153 C "C3'" . G   C 3 24  ? 135.551 131.754 106.539 1.00 37.34  ? -2  G   B "C3'" 1 
ATOM 3154 O "O3'" . G   C 3 24  ? 136.768 132.108 107.169 1.00 37.34  ? -2  G   B "O3'" 1 
ATOM 3155 C "C2'" . G   C 3 24  ? 134.334 132.483 107.090 1.00 37.34  ? -2  G   B "C2'" 1 
ATOM 3156 O "O2'" . G   C 3 24  ? 134.628 133.854 107.307 1.00 37.34  ? -2  G   B "O2'" 1 
ATOM 3157 C "C1'" . G   C 3 24  ? 133.364 132.382 105.917 1.00 37.34  ? -2  G   B "C1'" 1 
ATOM 3158 N N9    . G   C 3 24  ? 132.462 131.226 106.021 1.00 37.34  ? -2  G   B N9    1 
ATOM 3159 C C8    . G   C 3 24  ? 132.362 130.234 105.078 1.00 37.34  ? -2  G   B C8    1 
ATOM 3160 N N7    . G   C 3 24  ? 131.480 129.326 105.378 1.00 37.34  ? -2  G   B N7    1 
ATOM 3161 C C5    . G   C 3 24  ? 130.962 129.754 106.588 1.00 37.34  ? -2  G   B C5    1 
ATOM 3162 C C6    . G   C 3 24  ? 129.966 129.162 107.394 1.00 37.34  ? -2  G   B C6    1 
ATOM 3163 O O6    . G   C 3 24  ? 129.342 128.119 107.185 1.00 37.34  ? -2  G   B O6    1 
ATOM 3164 N N1    . G   C 3 24  ? 129.736 129.908 108.539 1.00 37.34  ? -2  G   B N1    1 
ATOM 3165 C C2    . G   C 3 24  ? 130.374 131.078 108.862 1.00 37.34  ? -2  G   B C2    1 
ATOM 3166 N N2    . G   C 3 24  ? 130.014 131.655 110.017 1.00 37.34  ? -2  G   B N2    1 
ATOM 3167 N N3    . G   C 3 24  ? 131.307 131.638 108.115 1.00 37.34  ? -2  G   B N3    1 
ATOM 3168 C C4    . G   C 3 24  ? 131.549 130.928 107.000 1.00 37.34  ? -2  G   B C4    1 
ATOM 3169 P P     . A   C 3 25  ? 137.423 131.131 108.259 1.00 34.68  ? -1  A   B P     1 
ATOM 3170 O OP1   . A   C 3 25  ? 138.836 131.540 108.458 1.00 34.68  ? -1  A   B OP1   1 
ATOM 3171 O OP2   . A   C 3 25  ? 137.110 129.730 107.876 1.00 34.68  ? -1  A   B OP2   1 
ATOM 3172 O "O5'" . A   C 3 25  ? 136.619 131.473 109.586 1.00 34.68  ? -1  A   B "O5'" 1 
ATOM 3173 C "C5'" . A   C 3 25  ? 136.475 132.817 110.012 1.00 34.68  ? -1  A   B "C5'" 1 
ATOM 3174 C "C4'" . A   C 3 25  ? 135.618 132.909 111.245 1.00 34.68  ? -1  A   B "C4'" 1 
ATOM 3175 O "O4'" . A   C 3 25  ? 134.228 132.720 110.894 1.00 34.68  ? -1  A   B "O4'" 1 
ATOM 3176 C "C3'" . A   C 3 25  ? 135.879 131.857 112.305 1.00 34.68  ? -1  A   B "C3'" 1 
ATOM 3177 O "O3'" . A   C 3 25  ? 136.986 132.181 113.124 1.00 34.68  ? -1  A   B "O3'" 1 
ATOM 3178 C "C2'" . A   C 3 25  ? 134.557 131.803 113.059 1.00 34.68  ? -1  A   B "C2'" 1 
ATOM 3179 O "O2'" . A   C 3 25  ? 134.466 132.871 113.989 1.00 34.68  ? -1  A   B "O2'" 1 
ATOM 3180 C "C1'" . A   C 3 25  ? 133.553 132.056 111.937 1.00 34.68  ? -1  A   B "C1'" 1 
ATOM 3181 N N9    . A   C 3 25  ? 132.972 130.817 111.394 1.00 34.68  ? -1  A   B N9    1 
ATOM 3182 C C8    . A   C 3 25  ? 133.229 130.245 110.176 1.00 34.68  ? -1  A   B C8    1 
ATOM 3183 N N7    . A   C 3 25  ? 132.553 129.149 109.951 1.00 34.68  ? -1  A   B N7    1 
ATOM 3184 C C5    . A   C 3 25  ? 131.794 128.999 111.098 1.00 34.68  ? -1  A   B C5    1 
ATOM 3185 C C6    . A   C 3 25  ? 130.863 128.029 111.481 1.00 34.68  ? -1  A   B C6    1 
ATOM 3186 N N6    . A   C 3 25  ? 130.538 126.996 110.713 1.00 34.68  ? -1  A   B N6    1 
ATOM 3187 N N1    . A   C 3 25  ? 130.280 128.157 112.688 1.00 34.68  ? -1  A   B N1    1 
ATOM 3188 C C2    . A   C 3 25  ? 130.621 129.203 113.449 1.00 34.68  ? -1  A   B C2    1 
ATOM 3189 N N3    . A   C 3 25  ? 131.482 130.184 113.197 1.00 34.68  ? -1  A   B N3    1 
ATOM 3190 C C4    . A   C 3 25  ? 132.038 130.020 111.992 1.00 34.68  ? -1  A   B C4    1 
ATOM 3191 P P     . C   C 3 26  ? 138.078 131.064 113.482 1.00 33.36  ? 0   C   B P     1 
ATOM 3192 O OP1   . C   C 3 26  ? 139.124 131.702 114.315 1.00 33.36  ? 0   C   B OP1   1 
ATOM 3193 O OP2   . C   C 3 26  ? 138.458 130.365 112.231 1.00 33.36  ? 0   C   B OP2   1 
ATOM 3194 O "O5'" . C   C 3 26  ? 137.283 130.036 114.397 1.00 33.36  ? 0   C   B "O5'" 1 
ATOM 3195 C "C5'" . C   C 3 26  ? 136.791 130.427 115.668 1.00 33.36  ? 0   C   B "C5'" 1 
ATOM 3196 C "C4'" . C   C 3 26  ? 135.712 129.493 116.146 1.00 33.36  ? 0   C   B "C4'" 1 
ATOM 3197 O "O4'" . C   C 3 26  ? 134.642 129.450 115.170 1.00 33.36  ? 0   C   B "O4'" 1 
ATOM 3198 C "C3'" . C   C 3 26  ? 136.121 128.040 116.315 1.00 33.36  ? 0   C   B "C3'" 1 
ATOM 3199 O "O3'" . C   C 3 26  ? 136.765 127.794 117.552 1.00 33.36  ? 0   C   B "O3'" 1 
ATOM 3200 C "C2'" . C   C 3 26  ? 134.797 127.303 116.160 1.00 33.36  ? 0   C   B "C2'" 1 
ATOM 3201 O "O2'" . C   C 3 26  ? 134.031 127.381 117.351 1.00 33.36  ? 0   C   B "O2'" 1 
ATOM 3202 C "C1'" . C   C 3 26  ? 134.107 128.149 115.095 1.00 33.36  ? 0   C   B "C1'" 1 
ATOM 3203 N N1    . C   C 3 26  ? 134.339 127.634 113.727 1.00 33.36  ? 0   C   B N1    1 
ATOM 3204 C C2    . C   C 3 26  ? 133.642 126.515 113.297 1.00 33.36  ? 0   C   B C2    1 
ATOM 3205 O O2    . C   C 3 26  ? 132.850 125.964 114.073 1.00 33.36  ? 0   C   B O2    1 
ATOM 3206 N N3    . C   C 3 26  ? 133.849 126.049 112.049 1.00 33.36  ? 0   C   B N3    1 
ATOM 3207 C C4    . C   C 3 26  ? 134.703 126.660 111.238 1.00 33.36  ? 0   C   B C4    1 
ATOM 3208 N N4    . C   C 3 26  ? 134.870 126.158 110.015 1.00 33.36  ? 0   C   B N4    1 
ATOM 3209 C C5    . C   C 3 26  ? 135.429 127.812 111.644 1.00 33.36  ? 0   C   B C5    1 
ATOM 3210 C C6    . C   C 3 26  ? 135.213 128.261 112.884 1.00 33.36  ? 0   C   B C6    1 
ATOM 3211 P P     . U   C 3 27  ? 138.333 127.451 117.599 1.00 36.69  ? 1   U   B P     1 
ATOM 3212 O OP1   . U   C 3 27  ? 139.093 128.705 117.378 1.00 36.69  ? 1   U   B OP1   1 
ATOM 3213 O OP2   . U   C 3 27  ? 138.577 126.276 116.726 1.00 36.69  ? 1   U   B OP2   1 
ATOM 3214 O "O5'" . U   C 3 27  ? 138.582 127.010 119.107 1.00 36.69  ? 1   U   B "O5'" 1 
ATOM 3215 C "C5'" . U   C 3 27  ? 138.793 127.983 120.124 1.00 36.69  ? 1   U   B "C5'" 1 
ATOM 3216 C "C4'" . U   C 3 27  ? 137.615 128.077 121.061 1.00 36.69  ? 1   U   B "C4'" 1 
ATOM 3217 O "O4'" . U   C 3 27  ? 138.010 127.586 122.372 1.00 36.69  ? 1   U   B "O4'" 1 
ATOM 3218 C "C3'" . U   C 3 27  ? 137.079 129.487 121.282 1.00 36.69  ? 1   U   B "C3'" 1 
ATOM 3219 O "O3'" . U   C 3 27  ? 135.672 129.431 121.495 1.00 36.69  ? 1   U   B "O3'" 1 
ATOM 3220 C "C2'" . U   C 3 27  ? 137.768 129.905 122.575 1.00 36.69  ? 1   U   B "C2'" 1 
ATOM 3221 O "O2'" . U   C 3 27  ? 137.104 130.923 123.291 1.00 36.69  ? 1   U   B "O2'" 1 
ATOM 3222 C "C1'" . U   C 3 27  ? 137.782 128.589 123.341 1.00 36.69  ? 1   U   B "C1'" 1 
ATOM 3223 N N1    . U   C 3 27  ? 138.835 128.503 124.361 1.00 36.69  ? 1   U   B N1    1 
ATOM 3224 C C2    . U   C 3 27  ? 138.540 127.822 125.525 1.00 36.69  ? 1   U   B C2    1 
ATOM 3225 O O2    . U   C 3 27  ? 137.463 127.286 125.723 1.00 36.69  ? 1   U   B O2    1 
ATOM 3226 N N3    . U   C 3 27  ? 139.559 127.777 126.443 1.00 36.69  ? 1   U   B N3    1 
ATOM 3227 C C4    . U   C 3 27  ? 140.811 128.343 126.320 1.00 36.69  ? 1   U   B C4    1 
ATOM 3228 O O4    . U   C 3 27  ? 141.623 128.219 127.239 1.00 36.69  ? 1   U   B O4    1 
ATOM 3229 C C5    . U   C 3 27  ? 141.034 129.038 125.089 1.00 36.69  ? 1   U   B C5    1 
ATOM 3230 C C6    . U   C 3 27  ? 140.061 129.096 124.174 1.00 36.69  ? 1   U   B C6    1 
ATOM 3231 P P     . C   C 3 28  ? 134.693 130.365 120.633 1.00 33.45  ? 2   C   B P     1 
ATOM 3232 O OP1   . C   C 3 28  ? 135.055 130.228 119.201 1.00 33.45  ? 2   C   B OP1   1 
ATOM 3233 O OP2   . C   C 3 28  ? 134.683 131.710 121.261 1.00 33.45  ? 2   C   B OP2   1 
ATOM 3234 O "O5'" . C   C 3 28  ? 133.257 129.715 120.849 1.00 33.45  ? 2   C   B "O5'" 1 
ATOM 3235 C "C5'" . C   C 3 28  ? 132.399 130.191 121.873 1.00 33.45  ? 2   C   B "C5'" 1 
ATOM 3236 C "C4'" . C   C 3 28  ? 132.001 129.089 122.820 1.00 33.45  ? 2   C   B "C4'" 1 
ATOM 3237 O "O4'" . C   C 3 28  ? 133.182 128.457 123.370 1.00 33.45  ? 2   C   B "O4'" 1 
ATOM 3238 C "C3'" . C   C 3 28  ? 131.214 129.520 124.042 1.00 33.45  ? 2   C   B "C3'" 1 
ATOM 3239 O "O3'" . C   C 3 28  ? 129.841 129.716 123.768 1.00 33.45  ? 2   C   B "O3'" 1 
ATOM 3240 C "C2'" . C   C 3 28  ? 131.476 128.392 125.028 1.00 33.45  ? 2   C   B "C2'" 1 
ATOM 3241 O "O2'" . C   C 3 28  ? 130.623 127.289 124.764 1.00 33.45  ? 2   C   B "O2'" 1 
ATOM 3242 C "C1'" . C   C 3 28  ? 132.911 127.992 124.675 1.00 33.45  ? 2   C   B "C1'" 1 
ATOM 3243 N N1    . C   C 3 28  ? 133.925 128.537 125.605 1.00 33.45  ? 2   C   B N1    1 
ATOM 3244 C C2    . C   C 3 28  ? 133.945 128.108 126.933 1.00 33.45  ? 2   C   B C2    1 
ATOM 3245 O O2    . C   C 3 28  ? 133.086 127.294 127.298 1.00 33.45  ? 2   C   B O2    1 
ATOM 3246 N N3    . C   C 3 28  ? 134.881 128.594 127.780 1.00 33.45  ? 2   C   B N3    1 
ATOM 3247 C C4    . C   C 3 28  ? 135.786 129.466 127.333 1.00 33.45  ? 2   C   B C4    1 
ATOM 3248 N N4    . C   C 3 28  ? 136.698 129.928 128.190 1.00 33.45  ? 2   C   B N4    1 
ATOM 3249 C C5    . C   C 3 28  ? 135.797 129.910 125.985 1.00 33.45  ? 2   C   B C5    1 
ATOM 3250 C C6    . C   C 3 28  ? 134.863 129.419 125.163 1.00 33.45  ? 2   C   B C6    1 
ATOM 3251 P P     . C   C 3 29  ? 129.059 130.938 124.447 1.00 30.46  ? 3   C   B P     1 
ATOM 3252 O OP1   . C   C 3 29  ? 127.840 131.220 123.653 1.00 30.46  ? 3   C   B OP1   1 
ATOM 3253 O OP2   . C   C 3 29  ? 130.054 132.017 124.679 1.00 30.46  ? 3   C   B OP2   1 
ATOM 3254 O "O5'" . C   C 3 29  ? 128.595 130.357 125.853 1.00 30.46  ? 3   C   B "O5'" 1 
ATOM 3255 C "C5'" . C   C 3 29  ? 127.701 129.256 125.926 1.00 30.46  ? 3   C   B "C5'" 1 
ATOM 3256 C "C4'" . C   C 3 29  ? 127.594 128.731 127.335 1.00 30.46  ? 3   C   B "C4'" 1 
ATOM 3257 O "O4'" . C   C 3 29  ? 128.849 128.117 127.727 1.00 30.46  ? 3   C   B "O4'" 1 
ATOM 3258 C "C3'" . C   C 3 29  ? 127.355 129.773 128.414 1.00 30.46  ? 3   C   B "C3'" 1 
ATOM 3259 O "O3'" . C   C 3 29  ? 126.010 130.192 128.513 1.00 30.46  ? 3   C   B "O3'" 1 
ATOM 3260 C "C2'" . C   C 3 29  ? 127.868 129.074 129.661 1.00 30.46  ? 3   C   B "C2'" 1 
ATOM 3261 O "O2'" . C   C 3 29  ? 126.929 128.113 130.119 1.00 30.46  ? 3   C   B "O2'" 1 
ATOM 3262 C "C1'" . C   C 3 29  ? 129.078 128.332 129.104 1.00 30.46  ? 3   C   B "C1'" 1 
ATOM 3263 N N1    . C   C 3 29  ? 130.323 129.110 129.267 1.00 30.46  ? 3   C   B N1    1 
ATOM 3264 C C2    . C   C 3 29  ? 130.918 129.145 130.525 1.00 30.46  ? 3   C   B C2    1 
ATOM 3265 O O2    . C   C 3 29  ? 130.376 128.525 131.451 1.00 30.46  ? 3   C   B O2    1 
ATOM 3266 N N3    . C   C 3 29  ? 132.062 129.842 130.695 1.00 30.46  ? 3   C   B N3    1 
ATOM 3267 C C4    . C   C 3 29  ? 132.603 130.488 129.665 1.00 30.46  ? 3   C   B C4    1 
ATOM 3268 N N4    . C   C 3 29  ? 133.730 131.169 129.871 1.00 30.46  ? 3   C   B N4    1 
ATOM 3269 C C5    . C   C 3 29  ? 132.014 130.468 128.374 1.00 30.46  ? 3   C   B C5    1 
ATOM 3270 C C6    . C   C 3 29  ? 130.883 129.775 128.222 1.00 30.46  ? 3   C   B C6    1 
ATOM 3271 P P     . C   C 3 30  ? 125.687 131.645 129.109 1.00 32.40  ? 4   C   B P     1 
ATOM 3272 O OP1   . C   C 3 30  ? 124.246 131.924 128.882 1.00 32.40  ? 4   C   B OP1   1 
ATOM 3273 O OP2   . C   C 3 30  ? 126.720 132.579 128.598 1.00 32.40  ? 4   C   B OP2   1 
ATOM 3274 O "O5'" . C   C 3 30  ? 125.930 131.480 130.674 1.00 32.40  ? 4   C   B "O5'" 1 
ATOM 3275 C "C5'" . C   C 3 30  ? 125.195 130.526 131.425 1.00 32.40  ? 4   C   B "C5'" 1 
ATOM 3276 C "C4'" . C   C 3 30  ? 125.703 130.419 132.841 1.00 32.40  ? 4   C   B "C4'" 1 
ATOM 3277 O "O4'" . C   C 3 30  ? 127.091 130.005 132.851 1.00 32.40  ? 4   C   B "O4'" 1 
ATOM 3278 C "C3'" . C   C 3 30  ? 125.705 131.702 133.649 1.00 32.40  ? 4   C   B "C3'" 1 
ATOM 3279 O "O3'" . C   C 3 30  ? 124.425 132.035 134.149 1.00 32.40  ? 4   C   B "O3'" 1 
ATOM 3280 C "C2'" . C   C 3 30  ? 126.727 131.404 134.735 1.00 32.40  ? 4   C   B "C2'" 1 
ATOM 3281 O "O2'" . C   C 3 30  ? 126.154 130.600 135.756 1.00 32.40  ? 4   C   B "O2'" 1 
ATOM 3282 C "C1'" . C   C 3 30  ? 127.744 130.558 133.974 1.00 32.40  ? 4   C   B "C1'" 1 
ATOM 3283 N N1    . C   C 3 30  ? 128.901 131.348 133.510 1.00 32.40  ? 4   C   B N1    1 
ATOM 3284 C C2    . C   C 3 30  ? 129.884 131.705 134.422 1.00 32.40  ? 4   C   B C2    1 
ATOM 3285 O O2    . C   C 3 30  ? 129.755 131.362 135.604 1.00 32.40  ? 4   C   B O2    1 
ATOM 3286 N N3    . C   C 3 30  ? 130.944 132.424 133.993 1.00 32.40  ? 4   C   B N3    1 
ATOM 3287 C C4    . C   C 3 30  ? 131.038 132.775 132.717 1.00 32.40  ? 4   C   B C4    1 
ATOM 3288 N N4    . C   C 3 30  ? 132.095 133.477 132.329 1.00 32.40  ? 4   C   B N4    1 
ATOM 3289 C C5    . C   C 3 30  ? 130.051 132.416 131.769 1.00 32.40  ? 4   C   B C5    1 
ATOM 3290 C C6    . C   C 3 30  ? 129.011 131.708 132.205 1.00 32.40  ? 4   C   B C6    1 
ATOM 3291 P P     . C   C 3 31  ? 123.951 133.581 134.296 1.00 39.85  ? 5   C   B P     1 
ATOM 3292 O OP1   . C   C 3 31  ? 122.512 133.582 134.662 1.00 39.85  ? 5   C   B OP1   1 
ATOM 3293 O OP2   . C   C 3 31  ? 124.400 134.341 133.096 1.00 39.85  ? 5   C   B OP2   1 
ATOM 3294 O "O5'" . C   C 3 31  ? 124.758 134.098 135.570 1.00 39.85  ? 5   C   B "O5'" 1 
ATOM 3295 C "C5'" . C   C 3 31  ? 124.630 133.436 136.842 1.00 39.85  ? 5   C   B "C5'" 1 
ATOM 3296 C "C4'" . C   C 3 31  ? 125.749 133.851 137.765 1.00 39.85  ? 5   C   B "C4'" 1 
ATOM 3297 O "O4'" . C   C 3 31  ? 127.027 133.426 137.220 1.00 39.85  ? 5   C   B "O4'" 1 
ATOM 3298 C "C3'" . C   C 3 31  ? 125.927 135.347 137.945 1.00 39.85  ? 5   C   B "C3'" 1 
ATOM 3299 O "O3'" . C   C 3 31  ? 124.972 135.915 138.840 1.00 39.85  ? 5   C   B "O3'" 1 
ATOM 3300 C "C2'" . C   C 3 31  ? 127.363 135.432 138.443 1.00 39.85  ? 5   C   B "C2'" 1 
ATOM 3301 O "O2'" . C   C 3 31  ? 127.501 135.138 139.818 1.00 39.85  ? 5   C   B "O2'" 1 
ATOM 3302 C "C1'" . C   C 3 31  ? 128.037 134.348 137.601 1.00 39.85  ? 5   C   B "C1'" 1 
ATOM 3303 N N1    . C   C 3 31  ? 128.677 134.875 136.384 1.00 39.85  ? 5   C   B N1    1 
ATOM 3304 C C2    . C   C 3 31  ? 129.890 135.558 136.503 1.00 39.85  ? 5   C   B C2    1 
ATOM 3305 O O2    . C   C 3 31  ? 130.395 135.692 137.628 1.00 39.85  ? 5   C   B O2    1 
ATOM 3306 N N3    . C   C 3 31  ? 130.487 136.043 135.391 1.00 39.85  ? 5   C   B N3    1 
ATOM 3307 C C4    . C   C 3 31  ? 129.912 135.877 134.198 1.00 39.85  ? 5   C   B C4    1 
ATOM 3308 N N4    . C   C 3 31  ? 130.534 136.378 133.128 1.00 39.85  ? 5   C   B N4    1 
ATOM 3309 C C5    . C   C 3 31  ? 128.672 135.192 134.049 1.00 39.85  ? 5   C   B C5    1 
ATOM 3310 C C6    . C   C 3 31  ? 128.095 134.710 135.157 1.00 39.85  ? 5   C   B C6    1 
ATOM 3311 P P     . U   C 3 32  ? 124.452 137.440 138.643 1.00 46.54  ? 6   U   B P     1 
ATOM 3312 O OP1   . U   C 3 32  ? 123.153 137.563 139.351 1.00 46.54  ? 6   U   B OP1   1 
ATOM 3313 O OP2   . U   C 3 32  ? 124.539 137.786 137.201 1.00 46.54  ? 6   U   B OP2   1 
ATOM 3314 O "O5'" . U   C 3 32  ? 125.530 138.310 139.421 1.00 46.54  ? 6   U   B "O5'" 1 
ATOM 3315 C "C5'" . U   C 3 32  ? 125.873 138.006 140.761 1.00 46.54  ? 6   U   B "C5'" 1 
ATOM 3316 C "C4'" . U   C 3 32  ? 127.065 138.807 141.206 1.00 46.54  ? 6   U   B "C4'" 1 
ATOM 3317 O "O4'" . U   C 3 32  ? 128.260 138.292 140.570 1.00 46.54  ? 6   U   B "O4'" 1 
ATOM 3318 C "C3'" . U   C 3 32  ? 127.031 140.275 140.821 1.00 46.54  ? 6   U   B "C3'" 1 
ATOM 3319 O "O3'" . U   C 3 32  ? 126.205 141.031 141.702 1.00 46.54  ? 6   U   B "O3'" 1 
ATOM 3320 C "C2'" . U   C 3 32  ? 128.513 140.644 140.762 1.00 46.54  ? 6   U   B "C2'" 1 
ATOM 3321 O "O2'" . U   C 3 32  ? 129.043 140.846 142.064 1.00 46.54  ? 6   U   B "O2'" 1 
ATOM 3322 C "C1'" . U   C 3 32  ? 129.120 139.352 140.213 1.00 46.54  ? 6   U   B "C1'" 1 
ATOM 3323 N N1    . U   C 3 32  ? 129.253 139.325 138.740 1.00 46.54  ? 6   U   B N1    1 
ATOM 3324 C C2    . U   C 3 32  ? 130.450 139.675 138.147 1.00 46.54  ? 6   U   B C2    1 
ATOM 3325 O O2    . U   C 3 32  ? 131.420 140.053 138.778 1.00 46.54  ? 6   U   B O2    1 
ATOM 3326 N N3    . U   C 3 32  ? 130.457 139.578 136.774 1.00 46.54  ? 6   U   B N3    1 
ATOM 3327 C C4    . U   C 3 32  ? 129.420 139.169 135.957 1.00 46.54  ? 6   U   B C4    1 
ATOM 3328 O O4    . U   C 3 32  ? 129.563 139.126 134.736 1.00 46.54  ? 6   U   B O4    1 
ATOM 3329 C C5    . U   C 3 32  ? 128.227 138.810 136.648 1.00 46.54  ? 6   U   B C5    1 
ATOM 3330 C C6    . U   C 3 32  ? 128.198 138.893 137.972 1.00 46.54  ? 6   U   B C6    1 
ATOM 3331 P P     . A   C 3 33  ? 125.252 142.218 141.143 1.00 56.91  ? 7   A   B P     1 
ATOM 3332 O OP1   . A   C 3 33  ? 124.547 142.820 142.302 1.00 56.91  ? 7   A   B OP1   1 
ATOM 3333 O OP2   . A   C 3 33  ? 124.458 141.694 139.997 1.00 56.91  ? 7   A   B OP2   1 
ATOM 3334 O "O5'" . A   C 3 33  ? 126.282 143.310 140.603 1.00 56.91  ? 7   A   B "O5'" 1 
ATOM 3335 C "C5'" . A   C 3 33  ? 126.885 144.260 141.501 1.00 56.91  ? 7   A   B "C5'" 1 
ATOM 3336 C "C4'" . A   C 3 33  ? 128.196 144.762 140.943 1.00 56.91  ? 7   A   B "C4'" 1 
ATOM 3337 O "O4'" . A   C 3 33  ? 128.848 143.694 140.210 1.00 56.91  ? 7   A   B "O4'" 1 
ATOM 3338 C "C3'" . A   C 3 33  ? 128.102 145.890 139.923 1.00 56.91  ? 7   A   B "C3'" 1 
ATOM 3339 O "O3'" . A   C 3 33  ? 128.013 147.164 140.551 1.00 56.91  ? 7   A   B "O3'" 1 
ATOM 3340 C "C2'" . A   C 3 33  ? 129.423 145.758 139.173 1.00 56.91  ? 7   A   B "C2'" 1 
ATOM 3341 O "O2'" . A   C 3 33  ? 130.501 146.409 139.813 1.00 56.91  ? 7   A   B "O2'" 1 
ATOM 3342 C "C1'" . A   C 3 33  ? 129.648 144.245 139.179 1.00 56.91  ? 7   A   B "C1'" 1 
ATOM 3343 N N9    . A   C 3 33  ? 129.288 143.602 137.916 1.00 56.91  ? 7   A   B N9    1 
ATOM 3344 C C8    . A   C 3 33  ? 128.221 142.777 137.660 1.00 56.91  ? 7   A   B C8    1 
ATOM 3345 N N7    . A   C 3 33  ? 128.165 142.354 136.420 1.00 56.91  ? 7   A   B N7    1 
ATOM 3346 C C5    . A   C 3 33  ? 129.269 142.940 135.818 1.00 56.91  ? 7   A   B C5    1 
ATOM 3347 C C6    . A   C 3 33  ? 129.772 142.886 134.506 1.00 56.91  ? 7   A   B C6    1 
ATOM 3348 N N6    . A   C 3 33  ? 129.203 142.185 133.523 1.00 56.91  ? 7   A   B N6    1 
ATOM 3349 N N1    . A   C 3 33  ? 130.893 143.589 134.234 1.00 56.91  ? 7   A   B N1    1 
ATOM 3350 C C2    . A   C 3 33  ? 131.462 144.293 135.220 1.00 56.91  ? 7   A   B C2    1 
ATOM 3351 N N3    . A   C 3 33  ? 131.086 144.422 136.490 1.00 56.91  ? 7   A   B N3    1 
ATOM 3352 C C4    . A   C 3 33  ? 129.970 143.712 136.727 1.00 56.91  ? 7   A   B C4    1 
ATOM 3353 P P     . C   C 3 34  ? 126.941 148.234 140.034 1.00 68.15  ? 8   C   B P     1 
ATOM 3354 O OP1   . C   C 3 34  ? 126.450 148.996 141.210 1.00 68.15  ? 8   C   B OP1   1 
ATOM 3355 O OP2   . C   C 3 34  ? 125.973 147.525 139.160 1.00 68.15  ? 8   C   B OP2   1 
ATOM 3356 O "O5'" . C   C 3 34  ? 127.811 149.213 139.127 1.00 68.15  ? 8   C   B "O5'" 1 
ATOM 3357 C "C5'" . C   C 3 34  ? 129.135 149.618 139.522 1.00 68.15  ? 8   C   B "C5'" 1 
ATOM 3358 C "C4'" . C   C 3 34  ? 130.022 149.744 138.307 1.00 68.15  ? 8   C   B "C4'" 1 
ATOM 3359 O "O4'" . C   C 3 34  ? 130.095 148.465 137.642 1.00 68.15  ? 8   C   B "O4'" 1 
ATOM 3360 C "C3'" . C   C 3 34  ? 129.523 150.702 137.238 1.00 68.15  ? 8   C   B "C3'" 1 
ATOM 3361 O "O3'" . C   C 3 34  ? 130.036 151.999 137.513 1.00 68.15  ? 8   C   B "O3'" 1 
ATOM 3362 C "C2'" . C   C 3 34  ? 130.116 150.144 135.942 1.00 68.15  ? 8   C   B "C2'" 1 
ATOM 3363 O "O2'" . C   C 3 34  ? 131.332 150.758 135.569 1.00 68.15  ? 8   C   B "O2'" 1 
ATOM 3364 C "C1'" . C   C 3 34  ? 130.347 148.664 136.269 1.00 68.15  ? 8   C   B "C1'" 1 
ATOM 3365 N N1    . C   C 3 34  ? 129.492 147.742 135.504 1.00 68.15  ? 8   C   B N1    1 
ATOM 3366 C C2    . C   C 3 34  ? 129.850 147.419 134.192 1.00 68.15  ? 8   C   B C2    1 
ATOM 3367 O O2    . C   C 3 34  ? 130.876 147.921 133.710 1.00 68.15  ? 8   C   B O2    1 
ATOM 3368 N N3    . C   C 3 34  ? 129.071 146.569 133.485 1.00 68.15  ? 8   C   B N3    1 
ATOM 3369 C C4    . C   C 3 34  ? 127.977 146.047 134.042 1.00 68.15  ? 8   C   B C4    1 
ATOM 3370 N N4    . C   C 3 34  ? 127.238 145.213 133.307 1.00 68.15  ? 8   C   B N4    1 
ATOM 3371 C C5    . C   C 3 34  ? 127.591 146.356 135.379 1.00 68.15  ? 8   C   B C5    1 
ATOM 3372 C C6    . C   C 3 34  ? 128.371 147.199 136.067 1.00 68.15  ? 8   C   B C6    1 
ATOM 3373 P P     . G   C 3 35  ? 129.275 153.294 136.970 1.00 87.17  ? 9   G   B P     1 
ATOM 3374 O OP1   . G   C 3 35  ? 129.334 154.338 138.024 1.00 87.17  ? 9   G   B OP1   1 
ATOM 3375 O OP2   . G   C 3 35  ? 127.959 152.865 136.435 1.00 87.17  ? 9   G   B OP2   1 
ATOM 3376 O "O5'" . G   C 3 35  ? 130.189 153.756 135.750 1.00 87.17  ? 9   G   B "O5'" 1 
ATOM 3377 C "C5'" . G   C 3 35  ? 129.604 154.323 134.566 1.00 87.17  ? 9   G   B "C5'" 1 
ATOM 3378 C "C4'" . G   C 3 35  ? 130.243 153.729 133.334 1.00 87.17  ? 9   G   B "C4'" 1 
ATOM 3379 O "O4'" . G   C 3 35  ? 130.103 152.294 133.377 1.00 87.17  ? 9   G   B "O4'" 1 
ATOM 3380 C "C3'" . G   C 3 35  ? 129.608 154.137 132.014 1.00 87.17  ? 9   G   B "C3'" 1 
ATOM 3381 O "O3'" . G   C 3 35  ? 130.263 155.291 131.503 1.00 87.17  ? 9   G   B "O3'" 1 
ATOM 3382 C "C2'" . G   C 3 35  ? 129.866 152.943 131.089 1.00 87.17  ? 9   G   B "C2'" 1 
ATOM 3383 O "O2'" . G   C 3 35  ? 130.988 153.123 130.249 1.00 87.17  ? 9   G   B "O2'" 1 
ATOM 3384 C "C1'" . G   C 3 35  ? 130.128 151.789 132.061 1.00 87.17  ? 9   G   B "C1'" 1 
ATOM 3385 N N9    . G   C 3 35  ? 129.173 150.688 131.958 1.00 87.17  ? 9   G   B N9    1 
ATOM 3386 C C8    . G   C 3 35  ? 129.304 149.568 131.174 1.00 87.17  ? 9   G   B C8    1 
ATOM 3387 N N7    . G   C 3 35  ? 128.302 148.740 131.291 1.00 87.17  ? 9   G   B N7    1 
ATOM 3388 C C5    . G   C 3 35  ? 127.456 149.350 132.207 1.00 87.17  ? 9   G   B C5    1 
ATOM 3389 C C6    . G   C 3 35  ? 126.208 148.924 132.730 1.00 87.17  ? 9   G   B C6    1 
ATOM 3390 O O6    . G   C 3 35  ? 125.577 147.891 132.476 1.00 87.17  ? 9   G   B O6    1 
ATOM 3391 N N1    . G   C 3 35  ? 125.692 149.847 133.634 1.00 87.17  ? 9   G   B N1    1 
ATOM 3392 C C2    . G   C 3 35  ? 126.295 151.027 133.989 1.00 87.17  ? 9   G   B C2    1 
ATOM 3393 N N2    . G   C 3 35  ? 125.636 151.783 134.879 1.00 87.17  ? 9   G   B N2    1 
ATOM 3394 N N3    . G   C 3 35  ? 127.457 151.437 133.508 1.00 87.17  ? 9   G   B N3    1 
ATOM 3395 C C4    . G   C 3 35  ? 127.979 150.554 132.630 1.00 87.17  ? 9   G   B C4    1 
ATOM 3396 P P     . U   C 3 36  ? 129.594 156.734 131.664 1.00 111.43 ? 10  U   B P     1 
ATOM 3397 O OP1   . U   C 3 36  ? 130.503 157.571 132.487 1.00 111.43 ? 10  U   B OP1   1 
ATOM 3398 O OP2   . U   C 3 36  ? 128.184 156.544 132.089 1.00 111.43 ? 10  U   B OP2   1 
ATOM 3399 O "O5'" . U   C 3 36  ? 129.601 157.296 130.174 1.00 111.43 ? 10  U   B "O5'" 1 
ATOM 3400 C "C5'" . U   C 3 36  ? 130.767 157.155 129.342 1.00 111.43 ? 10  U   B "C5'" 1 
ATOM 3401 C "C4'" . U   C 3 36  ? 130.424 156.376 128.095 1.00 111.43 ? 10  U   B "C4'" 1 
ATOM 3402 O "O4'" . U   C 3 36  ? 129.994 155.050 128.467 1.00 111.43 ? 10  U   B "O4'" 1 
ATOM 3403 C "C3'" . U   C 3 36  ? 129.255 156.917 127.285 1.00 111.43 ? 10  U   B "C3'" 1 
ATOM 3404 O "O3'" . U   C 3 36  ? 129.678 157.923 126.373 1.00 111.43 ? 10  U   B "O3'" 1 
ATOM 3405 C "C2'" . U   C 3 36  ? 128.717 155.683 126.552 1.00 111.43 ? 10  U   B "C2'" 1 
ATOM 3406 O "O2'" . U   C 3 36  ? 129.197 155.564 125.229 1.00 111.43 ? 10  U   B "O2'" 1 
ATOM 3407 C "C1'" . U   C 3 36  ? 129.211 154.519 127.421 1.00 111.43 ? 10  U   B "C1'" 1 
ATOM 3408 N N1    . U   C 3 36  ? 128.154 153.662 127.986 1.00 111.43 ? 10  U   B N1    1 
ATOM 3409 C C2    . U   C 3 36  ? 127.309 154.182 128.953 1.00 111.43 ? 10  U   B C2    1 
ATOM 3410 O O2    . U   C 3 36  ? 127.397 155.323 129.372 1.00 111.43 ? 10  U   B O2    1 
ATOM 3411 N N3    . U   C 3 36  ? 126.348 153.313 129.403 1.00 111.43 ? 10  U   B N3    1 
ATOM 3412 C C4    . U   C 3 36  ? 126.144 152.010 129.003 1.00 111.43 ? 10  U   B C4    1 
ATOM 3413 O O4    . U   C 3 36  ? 125.237 151.353 129.516 1.00 111.43 ? 10  U   B O4    1 
ATOM 3414 C C5    . U   C 3 36  ? 127.055 151.547 128.002 1.00 111.43 ? 10  U   B C5    1 
ATOM 3415 C C6    . U   C 3 36  ? 128.005 152.369 127.539 1.00 111.43 ? 10  U   B C6    1 
ATOM 3416 P P     . G   C 3 37  ? 129.071 159.398 126.481 1.00 125.68 ? 11  G   B P     1 
ATOM 3417 O OP1   . G   C 3 37  ? 130.144 160.364 126.133 1.00 125.68 ? 11  G   B OP1   1 
ATOM 3418 O OP2   . G   C 3 37  ? 128.373 159.514 127.787 1.00 125.68 ? 11  G   B OP2   1 
ATOM 3419 O "O5'" . G   C 3 37  ? 127.976 159.421 125.326 1.00 125.68 ? 11  G   B "O5'" 1 
ATOM 3420 C "C5'" . G   C 3 37  ? 126.578 159.247 125.624 1.00 125.68 ? 11  G   B "C5'" 1 
ATOM 3421 C "C4'" . G   C 3 37  ? 125.871 158.646 124.435 1.00 125.68 ? 11  G   B "C4'" 1 
ATOM 3422 O "O4'" . G   C 3 37  ? 126.263 157.253 124.301 1.00 125.68 ? 11  G   B "O4'" 1 
ATOM 3423 C "C3'" . G   C 3 37  ? 124.352 158.612 124.515 1.00 125.68 ? 11  G   B "C3'" 1 
ATOM 3424 O "O3'" . G   C 3 37  ? 123.773 159.846 124.084 1.00 125.68 ? 11  G   B "O3'" 1 
ATOM 3425 C "C2'" . G   C 3 37  ? 124.014 157.456 123.582 1.00 125.68 ? 11  G   B "C2'" 1 
ATOM 3426 O "O2'" . G   C 3 37  ? 124.019 157.817 122.216 1.00 125.68 ? 11  G   B "O2'" 1 
ATOM 3427 C "C1'" . G   C 3 37  ? 125.149 156.478 123.889 1.00 125.68 ? 11  G   B "C1'" 1 
ATOM 3428 N N9    . G   C 3 37  ? 124.820 155.543 124.959 1.00 125.68 ? 11  G   B N9    1 
ATOM 3429 C C8    . G   C 3 37  ? 125.343 155.520 126.229 1.00 125.68 ? 11  G   B C8    1 
ATOM 3430 N N7    . G   C 3 37  ? 124.847 154.567 126.971 1.00 125.68 ? 11  G   B N7    1 
ATOM 3431 C C5    . G   C 3 37  ? 123.941 153.922 126.141 1.00 125.68 ? 11  G   B C5    1 
ATOM 3432 C C6    . G   C 3 37  ? 123.096 152.811 126.392 1.00 125.68 ? 11  G   B C6    1 
ATOM 3433 O O6    . G   C 3 37  ? 122.977 152.151 127.430 1.00 125.68 ? 11  G   B O6    1 
ATOM 3434 N N1    . G   C 3 37  ? 122.338 152.484 125.272 1.00 125.68 ? 11  G   B N1    1 
ATOM 3435 C C2    . G   C 3 37  ? 122.380 153.143 124.069 1.00 125.68 ? 11  G   B C2    1 
ATOM 3436 N N2    . G   C 3 37  ? 121.568 152.676 123.110 1.00 125.68 ? 11  G   B N2    1 
ATOM 3437 N N3    . G   C 3 37  ? 123.162 154.181 123.823 1.00 125.68 ? 11  G   B N3    1 
ATOM 3438 C C4    . G   C 3 37  ? 123.910 154.514 124.896 1.00 125.68 ? 11  G   B C4    1 
ATOM 3439 P P     . C   C 3 38  ? 122.275 160.280 124.529 1.00 136.04 ? 12  C   B P     1 
ATOM 3440 O OP1   . C   C 3 38  ? 121.996 161.604 123.918 1.00 136.04 ? 12  C   B OP1   1 
ATOM 3441 O OP2   . C   C 3 38  ? 122.134 160.109 125.997 1.00 136.04 ? 12  C   B OP2   1 
ATOM 3442 O "O5'" . C   C 3 38  ? 121.344 159.203 123.813 1.00 136.04 ? 12  C   B "O5'" 1 
ATOM 3443 C "C5'" . C   C 3 38  ? 120.004 159.514 123.456 1.00 136.04 ? 12  C   B "C5'" 1 
ATOM 3444 C "C4'" . C   C 3 38  ? 119.061 158.392 123.815 1.00 136.04 ? 12  C   B "C4'" 1 
ATOM 3445 O "O4'" . C   C 3 38  ? 119.822 157.175 124.034 1.00 136.04 ? 12  C   B "O4'" 1 
ATOM 3446 C "C3'" . C   C 3 38  ? 118.269 158.578 125.103 1.00 136.04 ? 12  C   B "C3'" 1 
ATOM 3447 O "O3'" . C   C 3 38  ? 117.100 159.359 124.924 1.00 136.04 ? 12  C   B "O3'" 1 
ATOM 3448 C "C2'" . C   C 3 38  ? 117.980 157.147 125.531 1.00 136.04 ? 12  C   B "C2'" 1 
ATOM 3449 O "O2'" . C   C 3 38  ? 116.897 156.610 124.786 1.00 136.04 ? 12  C   B "O2'" 1 
ATOM 3450 C "C1'" . C   C 3 38  ? 119.262 156.436 125.097 1.00 136.04 ? 12  C   B "C1'" 1 
ATOM 3451 N N1    . C   C 3 38  ? 120.265 156.361 126.186 1.00 136.04 ? 12  C   B N1    1 
ATOM 3452 C C2    . C   C 3 38  ? 120.037 155.555 127.306 1.00 136.04 ? 12  C   B C2    1 
ATOM 3453 O O2    . C   C 3 38  ? 118.996 154.894 127.410 1.00 136.04 ? 12  C   B O2    1 
ATOM 3454 N N3    . C   C 3 38  ? 120.970 155.492 128.282 1.00 136.04 ? 12  C   B N3    1 
ATOM 3455 C C4    . C   C 3 38  ? 122.096 156.199 128.178 1.00 136.04 ? 12  C   B C4    1 
ATOM 3456 N N4    . C   C 3 38  ? 122.987 156.103 129.166 1.00 136.04 ? 12  C   B N4    1 
ATOM 3457 C C5    . C   C 3 38  ? 122.359 157.026 127.052 1.00 136.04 ? 12  C   B C5    1 
ATOM 3458 C C6    . C   C 3 38  ? 121.430 157.069 126.090 1.00 136.04 ? 12  C   B C6    1 
ATOM 3459 P P     . U   C 3 39  ? 116.456 160.161 126.160 1.00 150.01 ? 13  U   B P     1 
ATOM 3460 O OP1   . U   C 3 39  ? 115.436 161.093 125.617 1.00 150.01 ? 13  U   B OP1   1 
ATOM 3461 O OP2   . U   C 3 39  ? 117.566 160.690 126.993 1.00 150.01 ? 13  U   B OP2   1 
ATOM 3462 O "O5'" . U   C 3 39  ? 115.697 159.041 127.004 1.00 150.01 ? 13  U   B "O5'" 1 
ATOM 3463 C "C5'" . U   C 3 39  ? 114.489 158.458 126.534 1.00 150.01 ? 13  U   B "C5'" 1 
ATOM 3464 C "C4'" . U   C 3 39  ? 113.952 157.440 127.509 1.00 150.01 ? 13  U   B "C4'" 1 
ATOM 3465 O "O4'" . U   C 3 39  ? 114.951 156.413 127.736 1.00 150.01 ? 13  U   B "O4'" 1 
ATOM 3466 C "C3'" . U   C 3 39  ? 113.624 157.961 128.902 1.00 150.01 ? 13  U   B "C3'" 1 
ATOM 3467 O "O3'" . U   C 3 39  ? 112.336 158.550 128.974 1.00 150.01 ? 13  U   B "O3'" 1 
ATOM 3468 C "C2'" . U   C 3 39  ? 113.766 156.721 129.774 1.00 150.01 ? 13  U   B "C2'" 1 
ATOM 3469 O "O2'" . U   C 3 39  ? 112.598 155.917 129.698 1.00 150.01 ? 13  U   B "O2'" 1 
ATOM 3470 C "C1'" . U   C 3 39  ? 114.907 155.979 129.077 1.00 150.01 ? 13  U   B "C1'" 1 
ATOM 3471 N N1    . U   C 3 39  ? 116.232 156.226 129.694 1.00 150.01 ? 13  U   B N1    1 
ATOM 3472 C C2    . U   C 3 39  ? 116.514 155.687 130.937 1.00 150.01 ? 13  U   B C2    1 
ATOM 3473 O O2    . U   C 3 39  ? 115.714 155.034 131.585 1.00 150.01 ? 13  U   B O2    1 
ATOM 3474 N N3    . U   C 3 39  ? 117.776 155.956 131.411 1.00 150.01 ? 13  U   B N3    1 
ATOM 3475 C C4    . U   C 3 39  ? 118.769 156.679 130.783 1.00 150.01 ? 13  U   B C4    1 
ATOM 3476 O O4    . U   C 3 39  ? 119.858 156.834 131.339 1.00 150.01 ? 13  U   B O4    1 
ATOM 3477 C C5    . U   C 3 39  ? 118.403 157.194 129.502 1.00 150.01 ? 13  U   B C5    1 
ATOM 3478 C C6    . U   C 3 39  ? 117.184 156.948 129.013 1.00 150.01 ? 13  U   B C6    1 
ATOM 3479 P P     . G   C 3 40  ? 112.092 159.876 129.848 1.00 157.56 ? 14  G   B P     1 
ATOM 3480 O OP1   . G   C 3 40  ? 110.715 160.356 129.567 1.00 157.56 ? 14  G   B OP1   1 
ATOM 3481 O OP2   . G   C 3 40  ? 113.245 160.786 129.633 1.00 157.56 ? 14  G   B OP2   1 
ATOM 3482 O "O5'" . G   C 3 40  ? 112.140 159.366 131.358 1.00 157.56 ? 14  G   B "O5'" 1 
ATOM 3483 C "C5'" . G   C 3 40  ? 111.167 158.460 131.859 1.00 157.56 ? 14  G   B "C5'" 1 
ATOM 3484 C "C4'" . G   C 3 40  ? 111.640 157.793 133.126 1.00 157.56 ? 14  G   B "C4'" 1 
ATOM 3485 O "O4'" . G   C 3 40  ? 112.839 157.025 132.850 1.00 157.56 ? 14  G   B "O4'" 1 
ATOM 3486 C "C3'" . G   C 3 40  ? 112.043 158.727 134.258 1.00 157.56 ? 14  G   B "C3'" 1 
ATOM 3487 O "O3'" . G   C 3 40  ? 110.931 159.163 135.022 1.00 157.56 ? 14  G   B "O3'" 1 
ATOM 3488 C "C2'" . G   C 3 40  ? 113.034 157.889 135.057 1.00 157.56 ? 14  G   B "C2'" 1 
ATOM 3489 O "O2'" . G   C 3 40  ? 112.351 156.991 135.920 1.00 157.56 ? 14  G   B "O2'" 1 
ATOM 3490 C "C1'" . G   C 3 40  ? 113.714 157.075 133.955 1.00 157.56 ? 14  G   B "C1'" 1 
ATOM 3491 N N9    . G   C 3 40  ? 114.994 157.663 133.515 1.00 157.56 ? 14  G   B N9    1 
ATOM 3492 C C8    . G   C 3 40  ? 115.236 158.315 132.330 1.00 157.56 ? 14  G   B C8    1 
ATOM 3493 N N7    . G   C 3 40  ? 116.470 158.718 132.202 1.00 157.56 ? 14  G   B N7    1 
ATOM 3494 C C5    . G   C 3 40  ? 117.085 158.307 133.375 1.00 157.56 ? 14  G   B C5    1 
ATOM 3495 C C6    . G   C 3 40  ? 118.427 158.464 133.809 1.00 157.56 ? 14  G   B C6    1 
ATOM 3496 O O6    . G   C 3 40  ? 119.367 159.015 133.224 1.00 157.56 ? 14  G   B O6    1 
ATOM 3497 N N1    . G   C 3 40  ? 118.625 157.897 135.063 1.00 157.56 ? 14  G   B N1    1 
ATOM 3498 C C2    . G   C 3 40  ? 117.659 157.262 135.804 1.00 157.56 ? 14  G   B C2    1 
ATOM 3499 N N2    . G   C 3 40  ? 118.047 156.779 136.992 1.00 157.56 ? 14  G   B N2    1 
ATOM 3500 N N3    . G   C 3 40  ? 116.406 157.109 135.411 1.00 157.56 ? 14  G   B N3    1 
ATOM 3501 C C4    . G   C 3 40  ? 116.190 157.652 134.195 1.00 157.56 ? 14  G   B C4    1 
ATOM 3502 P P     . C   C 3 41  ? 110.689 160.728 135.295 1.00 168.98 ? 15  C   B P     1 
ATOM 3503 O OP1   . C   C 3 41  ? 109.229 160.987 135.204 1.00 168.98 ? 15  C   B OP1   1 
ATOM 3504 O OP2   . C   C 3 41  ? 111.625 161.495 134.436 1.00 168.98 ? 15  C   B OP2   1 
ATOM 3505 O "O5'" . C   C 3 41  ? 111.130 160.930 136.813 1.00 168.98 ? 15  C   B "O5'" 1 
ATOM 3506 C "C5'" . C   C 3 41  ? 110.568 160.140 137.852 1.00 168.98 ? 15  C   B "C5'" 1 
ATOM 3507 C "C4'" . C   C 3 41  ? 111.505 160.041 139.029 1.00 168.98 ? 15  C   B "C4'" 1 
ATOM 3508 O "O4'" . C   C 3 41  ? 112.778 159.511 138.585 1.00 168.98 ? 15  C   B "O4'" 1 
ATOM 3509 C "C3'" . C   C 3 41  ? 111.853 161.359 139.710 1.00 168.98 ? 15  C   B "C3'" 1 
ATOM 3510 O "O3'" . C   C 3 41  ? 110.870 161.731 140.665 1.00 168.98 ? 15  C   B "O3'" 1 
ATOM 3511 C "C2'" . C   C 3 41  ? 113.231 161.090 140.307 1.00 168.98 ? 15  C   B "C2'" 1 
ATOM 3512 O "O2'" . C   C 3 41  ? 113.118 160.411 141.549 1.00 168.98 ? 15  C   B "O2'" 1 
ATOM 3513 C "C1'" . C   C 3 41  ? 113.836 160.126 139.284 1.00 168.98 ? 15  C   B "C1'" 1 
ATOM 3514 N N1    . C   C 3 41  ? 114.722 160.785 138.295 1.00 168.98 ? 15  C   B N1    1 
ATOM 3515 C C2    . C   C 3 41  ? 116.082 160.930 138.585 1.00 168.98 ? 15  C   B C2    1 
ATOM 3516 O O2    . C   C 3 41  ? 116.508 160.529 139.679 1.00 168.98 ? 15  C   B O2    1 
ATOM 3517 N N3    . C   C 3 41  ? 116.896 161.510 137.672 1.00 168.98 ? 15  C   B N3    1 
ATOM 3518 C C4    . C   C 3 41  ? 116.400 161.929 136.506 1.00 168.98 ? 15  C   B C4    1 
ATOM 3519 N N4    . C   C 3 41  ? 117.238 162.497 135.636 1.00 168.98 ? 15  C   B N4    1 
ATOM 3520 C C5    . C   C 3 41  ? 115.023 161.784 136.177 1.00 168.98 ? 15  C   B C5    1 
ATOM 3521 C C6    . C   C 3 41  ? 114.232 161.208 137.089 1.00 168.98 ? 15  C   B C6    1 
ATOM 3522 P P     . U   C 3 42  ? 111.115 162.934 141.705 1.00 180.43 ? 16  U   B P     1 
ATOM 3523 O OP1   . U   C 3 42  ? 111.941 162.434 142.834 1.00 180.43 ? 16  U   B OP1   1 
ATOM 3524 O OP2   . U   C 3 42  ? 109.793 163.544 141.996 1.00 180.43 ? 16  U   B OP2   1 
ATOM 3525 O "O5'" . U   C 3 42  ? 111.966 164.000 140.887 1.00 180.43 ? 16  U   B "O5'" 1 
ATOM 3526 C "C5'" . U   C 3 42  ? 112.338 165.236 141.478 1.00 180.43 ? 16  U   B "C5'" 1 
ATOM 3527 C "C4'" . U   C 3 42  ? 113.728 165.171 142.056 1.00 180.43 ? 16  U   B "C4'" 1 
ATOM 3528 O "O4'" . U   C 3 42  ? 114.606 164.481 141.128 1.00 180.43 ? 16  U   B "O4'" 1 
ATOM 3529 C "C3'" . U   C 3 42  ? 114.411 166.509 142.294 1.00 180.43 ? 16  U   B "C3'" 1 
ATOM 3530 O "O3'" . U   C 3 42  ? 114.025 167.119 143.513 1.00 180.43 ? 16  U   B "O3'" 1 
ATOM 3531 C "C2'" . U   C 3 42  ? 115.888 166.146 142.230 1.00 180.43 ? 16  U   B "C2'" 1 
ATOM 3532 O "O2'" . U   C 3 42  ? 116.311 165.550 143.449 1.00 180.43 ? 16  U   B "O2'" 1 
ATOM 3533 C "C1'" . U   C 3 42  ? 115.887 165.072 141.142 1.00 180.43 ? 16  U   B "C1'" 1 
ATOM 3534 N N1    . U   C 3 42  ? 116.152 165.631 139.796 1.00 180.43 ? 16  U   B N1    1 
ATOM 3535 C C2    . U   C 3 42  ? 117.453 165.953 139.460 1.00 180.43 ? 16  U   B C2    1 
ATOM 3536 O O2    . U   C 3 42  ? 118.395 165.806 140.221 1.00 180.43 ? 16  U   B O2    1 
ATOM 3537 N N3    . U   C 3 42  ? 117.612 166.462 138.194 1.00 180.43 ? 16  U   B N3    1 
ATOM 3538 C C4    . U   C 3 42  ? 116.630 166.673 137.248 1.00 180.43 ? 16  U   B C4    1 
ATOM 3539 O O4    . U   C 3 42  ? 116.934 167.138 136.149 1.00 180.43 ? 16  U   B O4    1 
ATOM 3540 C C5    . U   C 3 42  ? 115.313 166.312 137.669 1.00 180.43 ? 16  U   B C5    1 
ATOM 3541 C C6    . U   C 3 42  ? 115.128 165.815 138.895 1.00 180.43 ? 16  U   B C6    1 
ATOM 3542 P P     . G   C 3 43  ? 113.520 168.645 143.531 1.00 188.35 ? 17  G   B P     1 
ATOM 3543 O OP1   . G   C 3 43  ? 112.650 168.824 144.721 1.00 188.35 ? 17  G   B OP1   1 
ATOM 3544 O OP2   . G   C 3 43  ? 112.994 168.972 142.181 1.00 188.35 ? 17  G   B OP2   1 
ATOM 3545 O "O5'" . G   C 3 43  ? 114.850 169.491 143.761 1.00 188.35 ? 17  G   B "O5'" 1 
ATOM 3546 C "C5'" . G   C 3 43  ? 115.526 169.459 145.008 1.00 188.35 ? 17  G   B "C5'" 1 
ATOM 3547 C "C4'" . G   C 3 43  ? 116.995 169.761 144.852 1.00 188.35 ? 17  G   B "C4'" 1 
ATOM 3548 O "O4'" . G   C 3 43  ? 117.602 168.795 143.955 1.00 188.35 ? 17  G   B "O4'" 1 
ATOM 3549 C "C3'" . G   C 3 43  ? 117.343 171.106 144.234 1.00 188.35 ? 17  G   B "C3'" 1 
ATOM 3550 O "O3'" . G   C 3 43  ? 117.283 172.173 145.166 1.00 188.35 ? 17  G   B "O3'" 1 
ATOM 3551 C "C2'" . G   C 3 43  ? 118.739 170.864 143.674 1.00 188.35 ? 17  G   B "C2'" 1 
ATOM 3552 O "O2'" . G   C 3 43  ? 119.713 170.938 144.704 1.00 188.35 ? 17  G   B "O2'" 1 
ATOM 3553 C "C1'" . G   C 3 43  ? 118.634 169.410 143.212 1.00 188.35 ? 17  G   B "C1'" 1 
ATOM 3554 N N9    . G   C 3 43  ? 118.317 169.300 141.775 1.00 188.35 ? 17  G   B N9    1 
ATOM 3555 C C8    . G   C 3 43  ? 117.083 169.133 141.194 1.00 188.35 ? 17  G   B C8    1 
ATOM 3556 N N7    . G   C 3 43  ? 117.134 169.068 139.891 1.00 188.35 ? 17  G   B N7    1 
ATOM 3557 C C5    . G   C 3 43  ? 118.483 169.202 139.591 1.00 188.35 ? 17  G   B C5    1 
ATOM 3558 C C6    . G   C 3 43  ? 119.157 169.214 138.340 1.00 188.35 ? 17  G   B C6    1 
ATOM 3559 O O6    . G   C 3 43  ? 118.682 169.100 137.204 1.00 188.35 ? 17  G   B O6    1 
ATOM 3560 N N1    . G   C 3 43  ? 120.528 169.376 138.503 1.00 188.35 ? 17  G   B N1    1 
ATOM 3561 C C2    . G   C 3 43  ? 121.168 169.511 139.709 1.00 188.35 ? 17  G   B C2    1 
ATOM 3562 N N2    . G   C 3 43  ? 122.499 169.658 139.662 1.00 188.35 ? 17  G   B N2    1 
ATOM 3563 N N3    . G   C 3 43  ? 120.555 169.504 140.879 1.00 188.35 ? 17  G   B N3    1 
ATOM 3564 C C4    . G   C 3 43  ? 119.223 169.348 140.745 1.00 188.35 ? 17  G   B C4    1 
ATOM 3565 P P     . A   C 3 44  ? 117.212 173.695 144.655 1.00 190.29 ? 18  A   B P     1 
ATOM 3566 O OP1   . A   C 3 44  ? 116.805 174.546 145.803 1.00 190.29 ? 18  A   B OP1   1 
ATOM 3567 O OP2   . A   C 3 44  ? 116.415 173.724 143.402 1.00 190.29 ? 18  A   B OP2   1 
ATOM 3568 O "O5'" . A   C 3 44  ? 118.721 174.051 144.290 1.00 190.29 ? 18  A   B "O5'" 1 
ATOM 3569 C "C5'" . A   C 3 44  ? 119.053 175.283 143.664 1.00 190.29 ? 18  A   B "C5'" 1 
ATOM 3570 C "C4'" . A   C 3 44  ? 120.430 175.233 143.051 1.00 190.29 ? 18  A   B "C4'" 1 
ATOM 3571 O "O4'" . A   C 3 44  ? 120.538 174.070 142.191 1.00 190.29 ? 18  A   B "O4'" 1 
ATOM 3572 C "C3'" . A   C 3 44  ? 120.801 176.396 142.145 1.00 190.29 ? 18  A   B "C3'" 1 
ATOM 3573 O "O3'" . A   C 3 44  ? 121.230 177.542 142.859 1.00 190.29 ? 18  A   B "O3'" 1 
ATOM 3574 C "C2'" . A   C 3 44  ? 121.875 175.789 141.253 1.00 190.29 ? 18  A   B "C2'" 1 
ATOM 3575 O "O2'" . A   C 3 44  ? 123.115 175.711 141.942 1.00 190.29 ? 18  A   B "O2'" 1 
ATOM 3576 C "C1'" . A   C 3 44  ? 121.337 174.371 141.066 1.00 190.29 ? 18  A   B "C1'" 1 
ATOM 3577 N N9    . A   C 3 44  ? 120.502 174.265 139.852 1.00 190.29 ? 18  A   B N9    1 
ATOM 3578 C C8    . A   C 3 44  ? 120.758 174.836 138.630 1.00 190.29 ? 18  A   B C8    1 
ATOM 3579 N N7    . A   C 3 44  ? 119.854 174.575 137.720 1.00 190.29 ? 18  A   B N7    1 
ATOM 3580 C C5    . A   C 3 44  ? 118.938 173.774 138.385 1.00 190.29 ? 18  A   B C5    1 
ATOM 3581 C C6    . A   C 3 44  ? 117.743 173.163 137.967 1.00 190.29 ? 18  A   B C6    1 
ATOM 3582 N N6    . A   C 3 44  ? 117.247 173.272 136.734 1.00 190.29 ? 18  A   B N6    1 
ATOM 3583 N N1    . A   C 3 44  ? 117.061 172.427 138.869 1.00 190.29 ? 18  A   B N1    1 
ATOM 3584 C C2    . A   C 3 44  ? 117.555 172.319 140.107 1.00 190.29 ? 18  A   B C2    1 
ATOM 3585 N N3    . A   C 3 44  ? 118.666 172.842 140.617 1.00 190.29 ? 18  A   B N3    1 
ATOM 3586 C C4    . A   C 3 44  ? 119.326 173.566 139.696 1.00 190.29 ? 18  A   B C4    1 
ATOM 3587 P P     . A   C 3 45  ? 120.458 178.940 142.677 1.00 190.78 ? 19  A   B P     1 
ATOM 3588 O OP1   . A   C 3 45  ? 121.083 179.933 143.587 1.00 190.78 ? 19  A   B OP1   1 
ATOM 3589 O OP2   . A   C 3 45  ? 119.000 178.675 142.772 1.00 190.78 ? 19  A   B OP2   1 
ATOM 3590 O "O5'" . A   C 3 45  ? 120.785 179.369 141.178 1.00 190.78 ? 19  A   B "O5'" 1 
ATOM 3591 C "C5'" . A   C 3 45  ? 122.109 179.697 140.788 1.00 190.78 ? 19  A   B "C5'" 1 
ATOM 3592 C "C4'" . A   C 3 45  ? 122.193 180.037 139.320 1.00 190.78 ? 19  A   B "C4'" 1 
ATOM 3593 O "O4'" . A   C 3 45  ? 122.043 178.837 138.520 1.00 190.78 ? 19  A   B "O4'" 1 
ATOM 3594 C "C3'" . A   C 3 45  ? 121.122 180.972 138.782 1.00 190.78 ? 19  A   B "C3'" 1 
ATOM 3595 O "O3'" . A   C 3 45  ? 121.379 182.334 139.078 1.00 190.78 ? 19  A   B "O3'" 1 
ATOM 3596 C "C2'" . A   C 3 45  ? 121.122 180.659 137.288 1.00 190.78 ? 19  A   B "C2'" 1 
ATOM 3597 O "O2'" . A   C 3 45  ? 122.172 181.352 136.630 1.00 190.78 ? 19  A   B "O2'" 1 
ATOM 3598 C "C1'" . A   C 3 45  ? 121.449 179.161 137.281 1.00 190.78 ? 19  A   B "C1'" 1 
ATOM 3599 N N9    . A   C 3 45  ? 120.261 178.310 137.059 1.00 190.78 ? 19  A   B N9    1 
ATOM 3600 C C8    . A   C 3 45  ? 120.022 177.534 135.951 1.00 190.78 ? 19  A   B C8    1 
ATOM 3601 N N7    . A   C 3 45  ? 118.891 176.875 135.991 1.00 190.78 ? 19  A   B N7    1 
ATOM 3602 C C5    . A   C 3 45  ? 118.343 177.240 137.210 1.00 190.78 ? 19  A   B C5    1 
ATOM 3603 C C6    . A   C 3 45  ? 117.144 176.878 137.848 1.00 190.78 ? 19  A   B C6    1 
ATOM 3604 N N6    . A   C 3 45  ? 116.250 176.038 137.321 1.00 190.78 ? 19  A   B N6    1 
ATOM 3605 N N1    . A   C 3 45  ? 116.886 177.414 139.060 1.00 190.78 ? 19  A   B N1    1 
ATOM 3606 C C2    . A   C 3 45  ? 117.781 178.257 139.586 1.00 190.78 ? 19  A   B C2    1 
ATOM 3607 N N3    . A   C 3 45  ? 118.941 178.671 139.084 1.00 190.78 ? 19  A   B N3    1 
ATOM 3608 C C4    . A   C 3 45  ? 119.172 178.123 137.880 1.00 190.78 ? 19  A   B C4    1 
ATOM 3609 P P     . G   C 3 46  ? 120.161 183.367 139.257 1.00 192.84 ? 20  G   B P     1 
ATOM 3610 O OP1   . G   C 3 46  ? 120.482 184.266 140.395 1.00 192.84 ? 20  G   B OP1   1 
ATOM 3611 O OP2   . G   C 3 46  ? 118.896 182.590 139.269 1.00 192.84 ? 20  G   B OP2   1 
ATOM 3612 O "O5'" . G   C 3 46  ? 120.192 184.233 137.920 1.00 192.84 ? 20  G   B "O5'" 1 
ATOM 3613 C "C5'" . G   C 3 46  ? 119.069 185.008 137.527 1.00 192.84 ? 20  G   B "C5'" 1 
ATOM 3614 C "C4'" . G   C 3 46  ? 118.978 185.120 136.026 1.00 192.84 ? 20  G   B "C4'" 1 
ATOM 3615 O "O4'" . G   C 3 46  ? 119.339 183.850 135.422 1.00 192.84 ? 20  G   B "O4'" 1 
ATOM 3616 C "C3'" . G   C 3 46  ? 117.597 185.421 135.464 1.00 192.84 ? 20  G   B "C3'" 1 
ATOM 3617 O "O3'" . G   C 3 46  ? 117.270 186.799 135.506 1.00 192.84 ? 20  G   B "O3'" 1 
ATOM 3618 C "C2'" . G   C 3 46  ? 117.679 184.853 134.054 1.00 192.84 ? 20  G   B "C2'" 1 
ATOM 3619 O "O2'" . G   C 3 46  ? 118.379 185.741 133.195 1.00 192.84 ? 20  G   B "O2'" 1 
ATOM 3620 C "C1'" . G   C 3 46  ? 118.545 183.615 134.279 1.00 192.84 ? 20  G   B "C1'" 1 
ATOM 3621 N N9    . G   C 3 46  ? 117.731 182.411 134.526 1.00 192.84 ? 20  G   B N9    1 
ATOM 3622 C C8    . G   C 3 46  ? 117.407 181.876 135.749 1.00 192.84 ? 20  G   B C8    1 
ATOM 3623 N N7    . G   C 3 46  ? 116.668 180.804 135.660 1.00 192.84 ? 20  G   B N7    1 
ATOM 3624 C C5    . G   C 3 46  ? 116.495 180.622 134.295 1.00 192.84 ? 20  G   B C5    1 
ATOM 3625 C C6    . G   C 3 46  ? 115.783 179.620 133.588 1.00 192.84 ? 20  G   B C6    1 
ATOM 3626 O O6    . G   C 3 46  ? 115.144 178.665 134.043 1.00 192.84 ? 20  G   B O6    1 
ATOM 3627 N N1    . G   C 3 46  ? 115.864 179.811 132.212 1.00 192.84 ? 20  G   B N1    1 
ATOM 3628 C C2    . G   C 3 46  ? 116.543 180.832 131.595 1.00 192.84 ? 20  G   B C2    1 
ATOM 3629 N N2    . G   C 3 46  ? 116.503 180.844 130.255 1.00 192.84 ? 20  G   B N2    1 
ATOM 3630 N N3    . G   C 3 46  ? 117.211 181.772 132.242 1.00 192.84 ? 20  G   B N3    1 
ATOM 3631 C C4    . G   C 3 46  ? 117.144 181.606 133.580 1.00 192.84 ? 20  G   B C4    1 
ATOM 3632 P P     . DC  D 4 4   ? 129.813 91.825  131.127 1.00 65.70  ? -6  DC  D P     1 
ATOM 3633 O OP1   . DC  D 4 4   ? 131.149 91.782  131.764 1.00 65.70  ? -6  DC  D OP1   1 
ATOM 3634 O OP2   . DC  D 4 4   ? 129.216 90.589  130.575 1.00 65.70  ? -6  DC  D OP2   1 
ATOM 3635 O "O5'" . DC  D 4 4   ? 128.768 92.462  132.157 1.00 65.70  ? -6  DC  D "O5'" 1 
ATOM 3636 C "C5'" . DC  D 4 4   ? 128.433 93.841  132.068 1.00 65.70  ? -6  DC  D "C5'" 1 
ATOM 3637 C "C4'" . DC  D 4 4   ? 127.557 94.259  133.234 1.00 65.70  ? -6  DC  D "C4'" 1 
ATOM 3638 O "O4'" . DC  D 4 4   ? 128.160 93.804  134.472 1.00 65.70  ? -6  DC  D "O4'" 1 
ATOM 3639 C "C3'" . DC  D 4 4   ? 127.396 95.759  133.406 1.00 65.70  ? -6  DC  D "C3'" 1 
ATOM 3640 O "O3'" . DC  D 4 4   ? 126.192 96.037  134.115 1.00 65.70  ? -6  DC  D "O3'" 1 
ATOM 3641 C "C2'" . DC  D 4 4   ? 128.626 96.108  134.234 1.00 65.70  ? -6  DC  D "C2'" 1 
ATOM 3642 C "C1'" . DC  D 4 4   ? 128.722 94.904  135.167 1.00 65.70  ? -6  DC  D "C1'" 1 
ATOM 3643 N N1    . DC  D 4 4   ? 130.121 94.554  135.547 1.00 65.70  ? -6  DC  D N1    1 
ATOM 3644 C C2    . DC  D 4 4   ? 130.475 94.478  136.898 1.00 65.70  ? -6  DC  D C2    1 
ATOM 3645 O O2    . DC  D 4 4   ? 129.617 94.704  137.759 1.00 65.70  ? -6  DC  D O2    1 
ATOM 3646 N N3    . DC  D 4 4   ? 131.750 94.156  137.225 1.00 65.70  ? -6  DC  D N3    1 
ATOM 3647 C C4    . DC  D 4 4   ? 132.647 93.920  136.266 1.00 65.70  ? -6  DC  D C4    1 
ATOM 3648 N N4    . DC  D 4 4   ? 133.892 93.607  136.638 1.00 65.70  ? -6  DC  D N4    1 
ATOM 3649 C C5    . DC  D 4 4   ? 132.306 93.993  134.885 1.00 65.70  ? -6  DC  D C5    1 
ATOM 3650 C C6    . DC  D 4 4   ? 131.044 94.310  134.574 1.00 65.70  ? -6  DC  D C6    1 
ATOM 3651 P P     . DC  D 4 5   ? 125.415 97.463  133.977 1.00 60.14  ? -5  DC  D P     1 
ATOM 3652 O OP1   . DC  D 4 5   ? 124.015 97.184  133.569 1.00 60.14  ? -5  DC  D OP1   1 
ATOM 3653 O OP2   . DC  D 4 5   ? 126.238 98.414  133.174 1.00 60.14  ? -5  DC  D OP2   1 
ATOM 3654 O "O5'" . DC  D 4 5   ? 125.385 98.009  135.474 1.00 60.14  ? -5  DC  D "O5'" 1 
ATOM 3655 C "C5'" . DC  D 4 5   ? 126.023 97.288  136.547 1.00 60.14  ? -5  DC  D "C5'" 1 
ATOM 3656 C "C4'" . DC  D 4 5   ? 126.812 98.233  137.423 1.00 60.14  ? -5  DC  D "C4'" 1 
ATOM 3657 O "O4'" . DC  D 4 5   ? 128.197 97.820  137.464 1.00 60.14  ? -5  DC  D "O4'" 1 
ATOM 3658 C "C3'" . DC  D 4 5   ? 126.813 99.697  136.967 1.00 60.14  ? -5  DC  D "C3'" 1 
ATOM 3659 O "O3'" . DC  D 4 5   ? 126.439 100.556 138.057 1.00 60.14  ? -5  DC  D "O3'" 1 
ATOM 3660 C "C2'" . DC  D 4 5   ? 128.241 99.938  136.510 1.00 60.14  ? -5  DC  D "C2'" 1 
ATOM 3661 C "C1'" . DC  D 4 5   ? 129.014 98.971  137.378 1.00 60.14  ? -5  DC  D "C1'" 1 
ATOM 3662 N N1    . DC  D 4 5   ? 130.314 98.564  136.830 1.00 60.14  ? -5  DC  D N1    1 
ATOM 3663 C C2    . DC  D 4 5   ? 131.180 97.826  137.637 1.00 60.14  ? -5  DC  D C2    1 
ATOM 3664 O O2    . DC  D 4 5   ? 130.819 97.529  138.785 1.00 60.14  ? -5  DC  D O2    1 
ATOM 3665 N N3    . DC  D 4 5   ? 132.382 97.449  137.147 1.00 60.14  ? -5  DC  D N3    1 
ATOM 3666 C C4    . DC  D 4 5   ? 132.731 97.788  135.904 1.00 60.14  ? -5  DC  D C4    1 
ATOM 3667 N N4    . DC  D 4 5   ? 133.927 97.395  135.461 1.00 60.14  ? -5  DC  D N4    1 
ATOM 3668 C C5    . DC  D 4 5   ? 131.868 98.545  135.060 1.00 60.14  ? -5  DC  D C5    1 
ATOM 3669 C C6    . DC  D 4 5   ? 130.682 98.912  135.560 1.00 60.14  ? -5  DC  D C6    1 
ATOM 3670 P P     . DA  D 4 6   ? 124.902 101.032 138.243 1.00 52.46  ? -4  DA  D P     1 
ATOM 3671 O OP1   . DA  D 4 6   ? 124.030 99.911  137.828 1.00 52.46  ? -4  DA  D OP1   1 
ATOM 3672 O OP2   . DA  D 4 6   ? 124.753 102.355 137.597 1.00 52.46  ? -4  DA  D OP2   1 
ATOM 3673 O "O5'" . DA  D 4 6   ? 124.758 101.240 139.822 1.00 52.46  ? -4  DA  D "O5'" 1 
ATOM 3674 C "C5'" . DA  D 4 6   ? 125.243 102.430 140.429 1.00 52.46  ? -4  DA  D "C5'" 1 
ATOM 3675 C "C4'" . DA  D 4 6   ? 126.468 102.151 141.283 1.00 52.46  ? -4  DA  D "C4'" 1 
ATOM 3676 O "O4'" . DA  D 4 6   ? 127.512 101.573 140.464 1.00 52.46  ? -4  DA  D "O4'" 1 
ATOM 3677 C "C3'" . DA  D 4 6   ? 127.080 103.391 141.944 1.00 52.46  ? -4  DA  D "C3'" 1 
ATOM 3678 O "O3'" . DA  D 4 6   ? 127.106 103.243 143.355 1.00 52.46  ? -4  DA  D "O3'" 1 
ATOM 3679 C "C2'" . DA  D 4 6   ? 128.491 103.477 141.360 1.00 52.46  ? -4  DA  D "C2'" 1 
ATOM 3680 C "C1'" . DA  D 4 6   ? 128.748 102.054 140.903 1.00 52.46  ? -4  DA  D "C1'" 1 
ATOM 3681 N N9    . DA  D 4 6   ? 129.698 101.972 139.800 1.00 52.46  ? -4  DA  D N9    1 
ATOM 3682 C C8    . DA  D 4 6   ? 129.511 102.398 138.516 1.00 52.46  ? -4  DA  D C8    1 
ATOM 3683 N N7    . DA  D 4 6   ? 130.549 102.207 137.738 1.00 52.46  ? -4  DA  D N7    1 
ATOM 3684 C C5    . DA  D 4 6   ? 131.480 101.614 138.571 1.00 52.46  ? -4  DA  D C5    1 
ATOM 3685 C C6    . DA  D 4 6   ? 132.792 101.159 138.356 1.00 52.46  ? -4  DA  D C6    1 
ATOM 3686 N N6    . DA  D 4 6   ? 133.417 101.234 137.176 1.00 52.46  ? -4  DA  D N6    1 
ATOM 3687 N N1    . DA  D 4 6   ? 133.438 100.617 139.401 1.00 52.46  ? -4  DA  D N1    1 
ATOM 3688 C C2    . DA  D 4 6   ? 132.815 100.540 140.574 1.00 52.46  ? -4  DA  D C2    1 
ATOM 3689 N N3    . DA  D 4 6   ? 131.595 100.933 140.901 1.00 52.46  ? -4  DA  D N3    1 
ATOM 3690 C C4    . DA  D 4 6   ? 130.971 101.464 139.844 1.00 52.46  ? -4  DA  D C4    1 
ATOM 3691 P P     . DA  D 4 7   ? 127.301 104.534 144.289 1.00 43.11  ? -3  DA  D P     1 
ATOM 3692 O OP1   . DA  D 4 7   ? 126.591 104.290 145.559 1.00 43.11  ? -3  DA  D OP1   1 
ATOM 3693 O OP2   . DA  D 4 7   ? 126.944 105.712 143.476 1.00 43.11  ? -3  DA  D OP2   1 
ATOM 3694 O "O5'" . DA  D 4 7   ? 128.878 104.591 144.548 1.00 43.11  ? -3  DA  D "O5'" 1 
ATOM 3695 C "C5'" . DA  D 4 7   ? 129.406 104.311 145.844 1.00 43.11  ? -3  DA  D "C5'" 1 
ATOM 3696 C "C4'" . DA  D 4 7   ? 130.721 103.564 145.737 1.00 43.11  ? -3  DA  D "C4'" 1 
ATOM 3697 O "O4'" . DA  D 4 7   ? 130.936 103.209 144.364 1.00 43.11  ? -3  DA  D "O4'" 1 
ATOM 3698 C "C3'" . DA  D 4 7   ? 131.958 104.362 146.150 1.00 43.11  ? -3  DA  D "C3'" 1 
ATOM 3699 O "O3'" . DA  D 4 7   ? 132.380 103.988 147.453 1.00 43.11  ? -3  DA  D "O3'" 1 
ATOM 3700 C "C2'" . DA  D 4 7   ? 133.021 103.996 145.113 1.00 43.11  ? -3  DA  D "C2'" 1 
ATOM 3701 C "C1'" . DA  D 4 7   ? 132.310 103.065 144.139 1.00 43.11  ? -3  DA  D "C1'" 1 
ATOM 3702 N N9    . DA  D 4 7   ? 132.584 103.383 142.742 1.00 43.11  ? -3  DA  D N9    1 
ATOM 3703 C C8    . DA  D 4 7   ? 131.743 103.987 141.856 1.00 43.11  ? -3  DA  D C8    1 
ATOM 3704 N N7    . DA  D 4 7   ? 132.262 104.155 140.665 1.00 43.11  ? -3  DA  D N7    1 
ATOM 3705 C C5    . DA  D 4 7   ? 133.530 103.626 140.779 1.00 43.11  ? -3  DA  D C5    1 
ATOM 3706 C C6    . DA  D 4 7   ? 134.586 103.493 139.861 1.00 43.11  ? -3  DA  D C6    1 
ATOM 3707 N N6    . DA  D 4 7   ? 134.510 103.909 138.596 1.00 43.11  ? -3  DA  D N6    1 
ATOM 3708 N N1    . DA  D 4 7   ? 135.727 102.912 140.296 1.00 43.11  ? -3  DA  D N1    1 
ATOM 3709 C C2    . DA  D 4 7   ? 135.792 102.497 141.566 1.00 43.11  ? -3  DA  D C2    1 
ATOM 3710 N N3    . DA  D 4 7   ? 134.865 102.567 142.517 1.00 43.11  ? -3  DA  D N3    1 
ATOM 3711 C C4    . DA  D 4 7   ? 133.749 103.150 142.054 1.00 43.11  ? -3  DA  D C4    1 
ATOM 3712 P P     . DT  D 4 8   ? 133.369 104.940 148.289 1.00 39.90  ? -2  DT  D P     1 
ATOM 3713 O OP1   . DT  D 4 8   ? 133.705 104.282 149.569 1.00 39.90  ? -2  DT  D OP1   1 
ATOM 3714 O OP2   . DT  D 4 8   ? 132.758 106.282 148.281 1.00 39.90  ? -2  DT  D OP2   1 
ATOM 3715 O "O5'" . DT  D 4 8   ? 134.693 105.002 147.412 1.00 39.90  ? -2  DT  D "O5'" 1 
ATOM 3716 C "C5'" . DT  D 4 8   ? 135.951 105.149 148.041 1.00 39.90  ? -2  DT  D "C5'" 1 
ATOM 3717 C "C4'" . DT  D 4 8   ? 137.061 104.629 147.142 1.00 39.90  ? -2  DT  D "C4'" 1 
ATOM 3718 O "O4'" . DT  D 4 8   ? 136.509 104.300 145.855 1.00 39.90  ? -2  DT  D "O4'" 1 
ATOM 3719 C "C3'" . DT  D 4 8   ? 138.169 105.628 146.846 1.00 39.90  ? -2  DT  D "C3'" 1 
ATOM 3720 O "O3'" . DT  D 4 8   ? 139.187 105.526 147.822 1.00 39.90  ? -2  DT  D "O3'" 1 
ATOM 3721 C "C2'" . DT  D 4 8   ? 138.682 105.196 145.473 1.00 39.90  ? -2  DT  D "C2'" 1 
ATOM 3722 C "C1'" . DT  D 4 8   ? 137.511 104.415 144.867 1.00 39.90  ? -2  DT  D "C1'" 1 
ATOM 3723 N N1    . DT  D 4 8   ? 136.911 105.049 143.651 1.00 39.90  ? -2  DT  D N1    1 
ATOM 3724 C C2    . DT  D 4 8   ? 137.649 105.130 142.497 1.00 39.90  ? -2  DT  D C2    1 
ATOM 3725 O O2    . DT  D 4 8   ? 138.792 104.722 142.401 1.00 39.90  ? -2  DT  D O2    1 
ATOM 3726 N N3    . DT  D 4 8   ? 137.000 105.715 141.448 1.00 39.90  ? -2  DT  D N3    1 
ATOM 3727 C C4    . DT  D 4 8   ? 135.713 106.214 141.438 1.00 39.90  ? -2  DT  D C4    1 
ATOM 3728 O O4    . DT  D 4 8   ? 135.215 106.722 140.440 1.00 39.90  ? -2  DT  D O4    1 
ATOM 3729 C C5    . DT  D 4 8   ? 134.998 106.092 142.676 1.00 39.90  ? -2  DT  D C5    1 
ATOM 3730 C C7    . DT  D 4 8   ? 133.598 106.598 142.786 1.00 39.90  ? -2  DT  D C7    1 
ATOM 3731 C C6    . DT  D 4 8   ? 135.620 105.520 143.706 1.00 39.90  ? -2  DT  D C6    1 
ATOM 3732 P P     . DT  D 4 9   ? 140.352 106.630 147.877 1.00 45.07  ? -1  DT  D P     1 
ATOM 3733 O OP1   . DT  D 4 9   ? 140.617 106.932 149.301 1.00 45.07  ? -1  DT  D OP1   1 
ATOM 3734 O OP2   . DT  D 4 9   ? 139.990 107.716 146.942 1.00 45.07  ? -1  DT  D OP2   1 
ATOM 3735 O "O5'" . DT  D 4 9   ? 141.619 105.887 147.259 1.00 45.07  ? -1  DT  D "O5'" 1 
ATOM 3736 C "C5'" . DT  D 4 9   ? 142.837 106.585 147.106 1.00 45.07  ? -1  DT  D "C5'" 1 
ATOM 3737 C "C4'" . DT  D 4 9   ? 143.245 106.621 145.649 1.00 45.07  ? -1  DT  D "C4'" 1 
ATOM 3738 O "O4'" . DT  D 4 9   ? 142.066 106.616 144.827 1.00 45.07  ? -1  DT  D "O4'" 1 
ATOM 3739 C "C3'" . DT  D 4 9   ? 144.048 107.856 145.230 1.00 45.07  ? -1  DT  D "C3'" 1 
ATOM 3740 O "O3'" . DT  D 4 9   ? 145.377 107.488 144.926 1.00 45.07  ? -1  DT  D "O3'" 1 
ATOM 3741 C "C2'" . DT  D 4 9   ? 143.314 108.395 143.988 1.00 45.07  ? -1  DT  D "C2'" 1 
ATOM 3742 C "C1'" . DT  D 4 9   ? 142.368 107.256 143.622 1.00 45.07  ? -1  DT  D "C1'" 1 
ATOM 3743 N N1    . DT  D 4 9   ? 141.092 107.713 143.003 1.00 45.07  ? -1  DT  D N1    1 
ATOM 3744 C C2    . DT  D 4 9   ? 141.061 108.005 141.664 1.00 45.07  ? -1  DT  D C2    1 
ATOM 3745 O O2    . DT  D 4 9   ? 142.035 107.918 140.937 1.00 45.07  ? -1  DT  D O2    1 
ATOM 3746 N N3    . DT  D 4 9   ? 139.843 108.415 141.199 1.00 45.07  ? -1  DT  D N3    1 
ATOM 3747 C C4    . DT  D 4 9   ? 138.678 108.549 141.923 1.00 45.07  ? -1  DT  D C4    1 
ATOM 3748 O O4    . DT  D 4 9   ? 137.629 108.923 141.414 1.00 45.07  ? -1  DT  D O4    1 
ATOM 3749 C C5    . DT  D 4 9   ? 138.779 108.222 143.316 1.00 45.07  ? -1  DT  D C5    1 
ATOM 3750 C C7    . DT  D 4 9   ? 137.578 108.337 144.202 1.00 45.07  ? -1  DT  D C7    1 
ATOM 3751 C C6    . DT  D 4 9   ? 139.965 107.823 143.785 1.00 45.07  ? -1  DT  D C6    1 
ATOM 3752 P P     . DC  D 4 10  ? 146.603 108.241 145.637 1.00 48.84  ? 0   DC  D P     1 
ATOM 3753 O OP1   . DC  D 4 10  ? 147.798 107.377 145.526 1.00 48.84  ? 0   DC  D OP1   1 
ATOM 3754 O OP2   . DC  D 4 10  ? 146.140 108.690 146.966 1.00 48.84  ? 0   DC  D OP2   1 
ATOM 3755 O "O5'" . DC  D 4 10  ? 146.830 109.536 144.734 1.00 48.84  ? 0   DC  D "O5'" 1 
ATOM 3756 C "C5'" . DC  D 4 10  ? 147.345 109.399 143.422 1.00 48.84  ? 0   DC  D "C5'" 1 
ATOM 3757 C "C4'" . DC  D 4 10  ? 146.828 110.506 142.520 1.00 48.84  ? 0   DC  D "C4'" 1 
ATOM 3758 O "O4'" . DC  D 4 10  ? 145.454 110.262 142.195 1.00 48.84  ? 0   DC  D "O4'" 1 
ATOM 3759 C "C3'" . DC  D 4 10  ? 146.824 111.893 143.138 1.00 48.84  ? 0   DC  D "C3'" 1 
ATOM 3760 O "O3'" . DC  D 4 10  ? 148.056 112.547 142.871 1.00 48.84  ? 0   DC  D "O3'" 1 
ATOM 3761 C "C2'" . DC  D 4 10  ? 145.648 112.600 142.438 1.00 48.84  ? 0   DC  D "C2'" 1 
ATOM 3762 C "C1'" . DC  D 4 10  ? 144.909 111.464 141.719 1.00 48.84  ? 0   DC  D "C1'" 1 
ATOM 3763 N N1    . DC  D 4 10  ? 143.442 111.455 141.965 1.00 48.84  ? 0   DC  D N1    1 
ATOM 3764 C C2    . DC  D 4 10  ? 142.573 111.041 140.949 1.00 48.84  ? 0   DC  D C2    1 
ATOM 3765 O O2    . DC  D 4 10  ? 143.043 110.681 139.862 1.00 48.84  ? 0   DC  D O2    1 
ATOM 3766 N N3    . DC  D 4 10  ? 141.240 111.042 141.187 1.00 48.84  ? 0   DC  D N3    1 
ATOM 3767 C C4    . DC  D 4 10  ? 140.774 111.435 142.371 1.00 48.84  ? 0   DC  D C4    1 
ATOM 3768 N N4    . DC  D 4 10  ? 139.453 111.422 142.558 1.00 48.84  ? 0   DC  D N4    1 
ATOM 3769 C C5    . DC  D 4 10  ? 141.643 111.864 143.416 1.00 48.84  ? 0   DC  D C5    1 
ATOM 3770 C C6    . DC  D 4 10  ? 142.957 111.859 143.171 1.00 48.84  ? 0   DC  D C6    1 
# 
