data_8WG9
# 
_entry.id   8WG9 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.398 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8WG9         pdb_00008wg9 10.2210/pdb8wg9/pdb 
WWPDB D_1300041189 ?            ?                   
EMDB  EMD-37506    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2024-11-27 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8WG9 
_pdbx_database_status.recvd_initial_deposition_date   2023-09-20 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
EMDB 'mGlu2-mGlu4 heterodimer bound mGlu4 agonist E7P' EMD-37506 'associated EM volume' 
EMDB .                                                 EMD-61799 'consensus EM volume'  
EMDB .                                                 EMD-61800 'focused EM volume'    
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              zhang_yan@zju.edu.cn 
_pdbx_contact_author.name_first         Yan 
_pdbx_contact_author.name_last          Zhang 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-2189-0244 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Zhang, Y.' 1 ? 
'Liu, J.'   2 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Structural basis of allosteric activation in a metabotropic glutamate heterodimer' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Zhang, Y.' 1 ? 
primary 'Liu, J.'   2 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Metabotropic glutamate receptor 4'     98365.320 1 ? ? ? ? 
2 polymer     man 'Metabotropic glutamate receptor 2'     93861.367 1 ? ? ? ? 
3 non-polymer syn '(2S)-2-amino-4-phosphonobutanoic acid' 183.100   1 ? ? ? ? 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;KPKGHPHMNSIRIDGDITLGGLFPVHGRGSEGKPCGELKKEKGIHRLEAMLFALDRINNDPDLLPNITLGARILDTCSRD
THALEQSLTFVQALIEKDGTEVRCGSGGPPIITKPERVVGVIGASGSSVSIMVANILRLFKIPQISYASTAPDLSDNSRY
DFFSRVVPSDTYQAQAMVDIVRALKWNYVSTVASEGSYGESGVEAFIQKSREDGGVCIAQSVKIPREPKAGEFDKIIRRL
LETSNARAVIIFANEDDIRRVLEAARRANQTGHFFWMGSDSWGSKIAPVLHLEEVAEGAVTILPKRMSVRGFDRYFSSRT
LDNNRRNIWFAEFWEDNFHCKLSRHALKKGSHVKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHALHAMHRDLCPGRV
GLCPRMDPVDGTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQYQLRNDSAEYKVIGSWTDHLHLRIERMHWPGSG
QQLPRSICSLPCQPGERKKTVKGMPCCWHCEPCTGYQYQVDRYTCKTCPYDMRPTENRTGCRPIPIIKLEWGSPWAVLPL
FLAVVGIAATLFVVITFVRYNDTPIVKASGRELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLGLGMSISYAALLT
KTNRIYRIFEQGKRSVSAPRFISPASQLAITFSLISLQLLGICVWFVVDPSHSVVDFQDQRTLDPRFARGVLKCDISDLS
LICLLGYSMLLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSADKLYIQTTTLTVSVSLSASV
SLGMLYMPKVYIILFHPEQNVPKRKRSLKAVVTAATMSNKFTQKGNFRPNGEAKSELCENLEAPALATKQTYVTYTNHAI
;
;KPKGHPHMNSIRIDGDITLGGLFPVHGRGSEGKPCGELKKEKGIHRLEAMLFALDRINNDPDLLPNITLGARILDTCSRD
THALEQSLTFVQALIEKDGTEVRCGSGGPPIITKPERVVGVIGASGSSVSIMVANILRLFKIPQISYASTAPDLSDNSRY
DFFSRVVPSDTYQAQAMVDIVRALKWNYVSTVASEGSYGESGVEAFIQKSREDGGVCIAQSVKIPREPKAGEFDKIIRRL
LETSNARAVIIFANEDDIRRVLEAARRANQTGHFFWMGSDSWGSKIAPVLHLEEVAEGAVTILPKRMSVRGFDRYFSSRT
LDNNRRNIWFAEFWEDNFHCKLSRHALKKGSHVKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHALHAMHRDLCPGRV
GLCPRMDPVDGTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQYQLRNDSAEYKVIGSWTDHLHLRIERMHWPGSG
QQLPRSICSLPCQPGERKKTVKGMPCCWHCEPCTGYQYQVDRYTCKTCPYDMRPTENRTGCRPIPIIKLEWGSPWAVLPL
FLAVVGIAATLFVVITFVRYNDTPIVKASGRELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLGLGMSISYAALLT
KTNRIYRIFEQGKRSVSAPRFISPASQLAITFSLISLQLLGICVWFVVDPSHSVVDFQDQRTLDPRFARGVLKCDISDLS
LICLLGYSMLLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSADKLYIQTTTLTVSVSLSASV
SLGMLYMPKVYIILFHPEQNVPKRKRSLKAVVTAATMSNKFTQKGNFRPNGEAKSELCENLEAPALATKQTYVTYTNHAI
;
B ? 
2 'polypeptide(L)' no no 
;EGPAKKVLTLEGDLVLGGLFPVHQKGGPAEDCGPVNEHRGIQRLEAMLFALDRINRDPHLLPGVRLGAHILDSCSKDTHA
LEQALDFVRASLSRGADGSRHICPDGSYATHGDAPTAITGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRY
DYFARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARARNICVATSEKVGRAMSRAAFEGVVRALL
QKPSARVAVLFTRSEDARELLAASQRLNASFTWVASDGWGALESVVAGSEGAAEGAITIELASYPISDFASYFQSLDPWN
NSRNPWFREFWEQRFRCSFRQRDCAAHSLRAVPFEQESKIMFVVNAVYAMAHALHNMHRALCPNTTRLCDAMRPVNGRRL
YKDFVLNVKFDAPFRPADTHNEVRFDRFGDGIGRYNIFTYLRAGSGRYRYQKVGYWAEGLTLDTSLIPWASPSAGPLPAS
RCSEPCLQNEVKSVQPGEVCCWLCIPCQPYEYRLDEFTCADCGLGYWPNASLTGCFELPQEYIRWGDAWAVGPVTIACLG
ALATLFVLGVFVRHNATPVVKASGRELCYILLGGVFLCYCMTFIFIAKPSTAVCTLRRLGLGTAFSVCYSALLTKTNRIA
RIFGGAREGAQRPRFISPASQVAICLALISGQLLIVVAWLVVEAPGTGKETAPERREVVTLRCNHRDASMLGSLAYNVLL
IALCTLYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCVSVSLSGSVVLGCLFAPKLHIIL
FQPQKNVVSHRAPTSRFGSAAARASSSLGQGSGSQFVPTVCNGREVVDSTTSSL
;
;EGPAKKVLTLEGDLVLGGLFPVHQKGGPAEDCGPVNEHRGIQRLEAMLFALDRINRDPHLLPGVRLGAHILDSCSKDTHA
LEQALDFVRASLSRGADGSRHICPDGSYATHGDAPTAITGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRY
DYFARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARARNICVATSEKVGRAMSRAAFEGVVRALL
QKPSARVAVLFTRSEDARELLAASQRLNASFTWVASDGWGALESVVAGSEGAAEGAITIELASYPISDFASYFQSLDPWN
NSRNPWFREFWEQRFRCSFRQRDCAAHSLRAVPFEQESKIMFVVNAVYAMAHALHNMHRALCPNTTRLCDAMRPVNGRRL
YKDFVLNVKFDAPFRPADTHNEVRFDRFGDGIGRYNIFTYLRAGSGRYRYQKVGYWAEGLTLDTSLIPWASPSAGPLPAS
RCSEPCLQNEVKSVQPGEVCCWLCIPCQPYEYRLDEFTCADCGLGYWPNASLTGCFELPQEYIRWGDAWAVGPVTIACLG
ALATLFVLGVFVRHNATPVVKASGRELCYILLGGVFLCYCMTFIFIAKPSTAVCTLRRLGLGTAFSVCYSALLTKTNRIA
RIFGGAREGAQRPRFISPASQVAICLALISGQLLIVVAWLVVEAPGTGKETAPERREVVTLRCNHRDASMLGSLAYNVLL
IALCTLYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCVSVSLSGSVVLGCLFAPKLHIIL
FQPQKNVVSHRAPTSRFGSAAARASSSLGQGSGSQFVPTVCNGREVVDSTTSSL
;
C ? 
# 
_pdbx_entity_nonpoly.entity_id   3 
_pdbx_entity_nonpoly.name        '(2S)-2-amino-4-phosphonobutanoic acid' 
_pdbx_entity_nonpoly.comp_id     E7P 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   LYS n 
1 2   PRO n 
1 3   LYS n 
1 4   GLY n 
1 5   HIS n 
1 6   PRO n 
1 7   HIS n 
1 8   MET n 
1 9   ASN n 
1 10  SER n 
1 11  ILE n 
1 12  ARG n 
1 13  ILE n 
1 14  ASP n 
1 15  GLY n 
1 16  ASP n 
1 17  ILE n 
1 18  THR n 
1 19  LEU n 
1 20  GLY n 
1 21  GLY n 
1 22  LEU n 
1 23  PHE n 
1 24  PRO n 
1 25  VAL n 
1 26  HIS n 
1 27  GLY n 
1 28  ARG n 
1 29  GLY n 
1 30  SER n 
1 31  GLU n 
1 32  GLY n 
1 33  LYS n 
1 34  PRO n 
1 35  CYS n 
1 36  GLY n 
1 37  GLU n 
1 38  LEU n 
1 39  LYS n 
1 40  LYS n 
1 41  GLU n 
1 42  LYS n 
1 43  GLY n 
1 44  ILE n 
1 45  HIS n 
1 46  ARG n 
1 47  LEU n 
1 48  GLU n 
1 49  ALA n 
1 50  MET n 
1 51  LEU n 
1 52  PHE n 
1 53  ALA n 
1 54  LEU n 
1 55  ASP n 
1 56  ARG n 
1 57  ILE n 
1 58  ASN n 
1 59  ASN n 
1 60  ASP n 
1 61  PRO n 
1 62  ASP n 
1 63  LEU n 
1 64  LEU n 
1 65  PRO n 
1 66  ASN n 
1 67  ILE n 
1 68  THR n 
1 69  LEU n 
1 70  GLY n 
1 71  ALA n 
1 72  ARG n 
1 73  ILE n 
1 74  LEU n 
1 75  ASP n 
1 76  THR n 
1 77  CYS n 
1 78  SER n 
1 79  ARG n 
1 80  ASP n 
1 81  THR n 
1 82  HIS n 
1 83  ALA n 
1 84  LEU n 
1 85  GLU n 
1 86  GLN n 
1 87  SER n 
1 88  LEU n 
1 89  THR n 
1 90  PHE n 
1 91  VAL n 
1 92  GLN n 
1 93  ALA n 
1 94  LEU n 
1 95  ILE n 
1 96  GLU n 
1 97  LYS n 
1 98  ASP n 
1 99  GLY n 
1 100 THR n 
1 101 GLU n 
1 102 VAL n 
1 103 ARG n 
1 104 CYS n 
1 105 GLY n 
1 106 SER n 
1 107 GLY n 
1 108 GLY n 
1 109 PRO n 
1 110 PRO n 
1 111 ILE n 
1 112 ILE n 
1 113 THR n 
1 114 LYS n 
1 115 PRO n 
1 116 GLU n 
1 117 ARG n 
1 118 VAL n 
1 119 VAL n 
1 120 GLY n 
1 121 VAL n 
1 122 ILE n 
1 123 GLY n 
1 124 ALA n 
1 125 SER n 
1 126 GLY n 
1 127 SER n 
1 128 SER n 
1 129 VAL n 
1 130 SER n 
1 131 ILE n 
1 132 MET n 
1 133 VAL n 
1 134 ALA n 
1 135 ASN n 
1 136 ILE n 
1 137 LEU n 
1 138 ARG n 
1 139 LEU n 
1 140 PHE n 
1 141 LYS n 
1 142 ILE n 
1 143 PRO n 
1 144 GLN n 
1 145 ILE n 
1 146 SER n 
1 147 TYR n 
1 148 ALA n 
1 149 SER n 
1 150 THR n 
1 151 ALA n 
1 152 PRO n 
1 153 ASP n 
1 154 LEU n 
1 155 SER n 
1 156 ASP n 
1 157 ASN n 
1 158 SER n 
1 159 ARG n 
1 160 TYR n 
1 161 ASP n 
1 162 PHE n 
1 163 PHE n 
1 164 SER n 
1 165 ARG n 
1 166 VAL n 
1 167 VAL n 
1 168 PRO n 
1 169 SER n 
1 170 ASP n 
1 171 THR n 
1 172 TYR n 
1 173 GLN n 
1 174 ALA n 
1 175 GLN n 
1 176 ALA n 
1 177 MET n 
1 178 VAL n 
1 179 ASP n 
1 180 ILE n 
1 181 VAL n 
1 182 ARG n 
1 183 ALA n 
1 184 LEU n 
1 185 LYS n 
1 186 TRP n 
1 187 ASN n 
1 188 TYR n 
1 189 VAL n 
1 190 SER n 
1 191 THR n 
1 192 VAL n 
1 193 ALA n 
1 194 SER n 
1 195 GLU n 
1 196 GLY n 
1 197 SER n 
1 198 TYR n 
1 199 GLY n 
1 200 GLU n 
1 201 SER n 
1 202 GLY n 
1 203 VAL n 
1 204 GLU n 
1 205 ALA n 
1 206 PHE n 
1 207 ILE n 
1 208 GLN n 
1 209 LYS n 
1 210 SER n 
1 211 ARG n 
1 212 GLU n 
1 213 ASP n 
1 214 GLY n 
1 215 GLY n 
1 216 VAL n 
1 217 CYS n 
1 218 ILE n 
1 219 ALA n 
1 220 GLN n 
1 221 SER n 
1 222 VAL n 
1 223 LYS n 
1 224 ILE n 
1 225 PRO n 
1 226 ARG n 
1 227 GLU n 
1 228 PRO n 
1 229 LYS n 
1 230 ALA n 
1 231 GLY n 
1 232 GLU n 
1 233 PHE n 
1 234 ASP n 
1 235 LYS n 
1 236 ILE n 
1 237 ILE n 
1 238 ARG n 
1 239 ARG n 
1 240 LEU n 
1 241 LEU n 
1 242 GLU n 
1 243 THR n 
1 244 SER n 
1 245 ASN n 
1 246 ALA n 
1 247 ARG n 
1 248 ALA n 
1 249 VAL n 
1 250 ILE n 
1 251 ILE n 
1 252 PHE n 
1 253 ALA n 
1 254 ASN n 
1 255 GLU n 
1 256 ASP n 
1 257 ASP n 
1 258 ILE n 
1 259 ARG n 
1 260 ARG n 
1 261 VAL n 
1 262 LEU n 
1 263 GLU n 
1 264 ALA n 
1 265 ALA n 
1 266 ARG n 
1 267 ARG n 
1 268 ALA n 
1 269 ASN n 
1 270 GLN n 
1 271 THR n 
1 272 GLY n 
1 273 HIS n 
1 274 PHE n 
1 275 PHE n 
1 276 TRP n 
1 277 MET n 
1 278 GLY n 
1 279 SER n 
1 280 ASP n 
1 281 SER n 
1 282 TRP n 
1 283 GLY n 
1 284 SER n 
1 285 LYS n 
1 286 ILE n 
1 287 ALA n 
1 288 PRO n 
1 289 VAL n 
1 290 LEU n 
1 291 HIS n 
1 292 LEU n 
1 293 GLU n 
1 294 GLU n 
1 295 VAL n 
1 296 ALA n 
1 297 GLU n 
1 298 GLY n 
1 299 ALA n 
1 300 VAL n 
1 301 THR n 
1 302 ILE n 
1 303 LEU n 
1 304 PRO n 
1 305 LYS n 
1 306 ARG n 
1 307 MET n 
1 308 SER n 
1 309 VAL n 
1 310 ARG n 
1 311 GLY n 
1 312 PHE n 
1 313 ASP n 
1 314 ARG n 
1 315 TYR n 
1 316 PHE n 
1 317 SER n 
1 318 SER n 
1 319 ARG n 
1 320 THR n 
1 321 LEU n 
1 322 ASP n 
1 323 ASN n 
1 324 ASN n 
1 325 ARG n 
1 326 ARG n 
1 327 ASN n 
1 328 ILE n 
1 329 TRP n 
1 330 PHE n 
1 331 ALA n 
1 332 GLU n 
1 333 PHE n 
1 334 TRP n 
1 335 GLU n 
1 336 ASP n 
1 337 ASN n 
1 338 PHE n 
1 339 HIS n 
1 340 CYS n 
1 341 LYS n 
1 342 LEU n 
1 343 SER n 
1 344 ARG n 
1 345 HIS n 
1 346 ALA n 
1 347 LEU n 
1 348 LYS n 
1 349 LYS n 
1 350 GLY n 
1 351 SER n 
1 352 HIS n 
1 353 VAL n 
1 354 LYS n 
1 355 LYS n 
1 356 CYS n 
1 357 THR n 
1 358 ASN n 
1 359 ARG n 
1 360 GLU n 
1 361 ARG n 
1 362 ILE n 
1 363 GLY n 
1 364 GLN n 
1 365 ASP n 
1 366 SER n 
1 367 ALA n 
1 368 TYR n 
1 369 GLU n 
1 370 GLN n 
1 371 GLU n 
1 372 GLY n 
1 373 LYS n 
1 374 VAL n 
1 375 GLN n 
1 376 PHE n 
1 377 VAL n 
1 378 ILE n 
1 379 ASP n 
1 380 ALA n 
1 381 VAL n 
1 382 TYR n 
1 383 ALA n 
1 384 MET n 
1 385 GLY n 
1 386 HIS n 
1 387 ALA n 
1 388 LEU n 
1 389 HIS n 
1 390 ALA n 
1 391 MET n 
1 392 HIS n 
1 393 ARG n 
1 394 ASP n 
1 395 LEU n 
1 396 CYS n 
1 397 PRO n 
1 398 GLY n 
1 399 ARG n 
1 400 VAL n 
1 401 GLY n 
1 402 LEU n 
1 403 CYS n 
1 404 PRO n 
1 405 ARG n 
1 406 MET n 
1 407 ASP n 
1 408 PRO n 
1 409 VAL n 
1 410 ASP n 
1 411 GLY n 
1 412 THR n 
1 413 GLN n 
1 414 LEU n 
1 415 LEU n 
1 416 LYS n 
1 417 TYR n 
1 418 ILE n 
1 419 ARG n 
1 420 ASN n 
1 421 VAL n 
1 422 ASN n 
1 423 PHE n 
1 424 SER n 
1 425 GLY n 
1 426 ILE n 
1 427 ALA n 
1 428 GLY n 
1 429 ASN n 
1 430 PRO n 
1 431 VAL n 
1 432 THR n 
1 433 PHE n 
1 434 ASN n 
1 435 GLU n 
1 436 ASN n 
1 437 GLY n 
1 438 ASP n 
1 439 ALA n 
1 440 PRO n 
1 441 GLY n 
1 442 ARG n 
1 443 TYR n 
1 444 ASP n 
1 445 ILE n 
1 446 TYR n 
1 447 GLN n 
1 448 TYR n 
1 449 GLN n 
1 450 LEU n 
1 451 ARG n 
1 452 ASN n 
1 453 ASP n 
1 454 SER n 
1 455 ALA n 
1 456 GLU n 
1 457 TYR n 
1 458 LYS n 
1 459 VAL n 
1 460 ILE n 
1 461 GLY n 
1 462 SER n 
1 463 TRP n 
1 464 THR n 
1 465 ASP n 
1 466 HIS n 
1 467 LEU n 
1 468 HIS n 
1 469 LEU n 
1 470 ARG n 
1 471 ILE n 
1 472 GLU n 
1 473 ARG n 
1 474 MET n 
1 475 HIS n 
1 476 TRP n 
1 477 PRO n 
1 478 GLY n 
1 479 SER n 
1 480 GLY n 
1 481 GLN n 
1 482 GLN n 
1 483 LEU n 
1 484 PRO n 
1 485 ARG n 
1 486 SER n 
1 487 ILE n 
1 488 CYS n 
1 489 SER n 
1 490 LEU n 
1 491 PRO n 
1 492 CYS n 
1 493 GLN n 
1 494 PRO n 
1 495 GLY n 
1 496 GLU n 
1 497 ARG n 
1 498 LYS n 
1 499 LYS n 
1 500 THR n 
1 501 VAL n 
1 502 LYS n 
1 503 GLY n 
1 504 MET n 
1 505 PRO n 
1 506 CYS n 
1 507 CYS n 
1 508 TRP n 
1 509 HIS n 
1 510 CYS n 
1 511 GLU n 
1 512 PRO n 
1 513 CYS n 
1 514 THR n 
1 515 GLY n 
1 516 TYR n 
1 517 GLN n 
1 518 TYR n 
1 519 GLN n 
1 520 VAL n 
1 521 ASP n 
1 522 ARG n 
1 523 TYR n 
1 524 THR n 
1 525 CYS n 
1 526 LYS n 
1 527 THR n 
1 528 CYS n 
1 529 PRO n 
1 530 TYR n 
1 531 ASP n 
1 532 MET n 
1 533 ARG n 
1 534 PRO n 
1 535 THR n 
1 536 GLU n 
1 537 ASN n 
1 538 ARG n 
1 539 THR n 
1 540 GLY n 
1 541 CYS n 
1 542 ARG n 
1 543 PRO n 
1 544 ILE n 
1 545 PRO n 
1 546 ILE n 
1 547 ILE n 
1 548 LYS n 
1 549 LEU n 
1 550 GLU n 
1 551 TRP n 
1 552 GLY n 
1 553 SER n 
1 554 PRO n 
1 555 TRP n 
1 556 ALA n 
1 557 VAL n 
1 558 LEU n 
1 559 PRO n 
1 560 LEU n 
1 561 PHE n 
1 562 LEU n 
1 563 ALA n 
1 564 VAL n 
1 565 VAL n 
1 566 GLY n 
1 567 ILE n 
1 568 ALA n 
1 569 ALA n 
1 570 THR n 
1 571 LEU n 
1 572 PHE n 
1 573 VAL n 
1 574 VAL n 
1 575 ILE n 
1 576 THR n 
1 577 PHE n 
1 578 VAL n 
1 579 ARG n 
1 580 TYR n 
1 581 ASN n 
1 582 ASP n 
1 583 THR n 
1 584 PRO n 
1 585 ILE n 
1 586 VAL n 
1 587 LYS n 
1 588 ALA n 
1 589 SER n 
1 590 GLY n 
1 591 ARG n 
1 592 GLU n 
1 593 LEU n 
1 594 SER n 
1 595 TYR n 
1 596 VAL n 
1 597 LEU n 
1 598 LEU n 
1 599 ALA n 
1 600 GLY n 
1 601 ILE n 
1 602 PHE n 
1 603 LEU n 
1 604 CYS n 
1 605 TYR n 
1 606 ALA n 
1 607 THR n 
1 608 THR n 
1 609 PHE n 
1 610 LEU n 
1 611 MET n 
1 612 ILE n 
1 613 ALA n 
1 614 GLU n 
1 615 PRO n 
1 616 ASP n 
1 617 LEU n 
1 618 GLY n 
1 619 THR n 
1 620 CYS n 
1 621 SER n 
1 622 LEU n 
1 623 ARG n 
1 624 ARG n 
1 625 ILE n 
1 626 PHE n 
1 627 LEU n 
1 628 GLY n 
1 629 LEU n 
1 630 GLY n 
1 631 MET n 
1 632 SER n 
1 633 ILE n 
1 634 SER n 
1 635 TYR n 
1 636 ALA n 
1 637 ALA n 
1 638 LEU n 
1 639 LEU n 
1 640 THR n 
1 641 LYS n 
1 642 THR n 
1 643 ASN n 
1 644 ARG n 
1 645 ILE n 
1 646 TYR n 
1 647 ARG n 
1 648 ILE n 
1 649 PHE n 
1 650 GLU n 
1 651 GLN n 
1 652 GLY n 
1 653 LYS n 
1 654 ARG n 
1 655 SER n 
1 656 VAL n 
1 657 SER n 
1 658 ALA n 
1 659 PRO n 
1 660 ARG n 
1 661 PHE n 
1 662 ILE n 
1 663 SER n 
1 664 PRO n 
1 665 ALA n 
1 666 SER n 
1 667 GLN n 
1 668 LEU n 
1 669 ALA n 
1 670 ILE n 
1 671 THR n 
1 672 PHE n 
1 673 SER n 
1 674 LEU n 
1 675 ILE n 
1 676 SER n 
1 677 LEU n 
1 678 GLN n 
1 679 LEU n 
1 680 LEU n 
1 681 GLY n 
1 682 ILE n 
1 683 CYS n 
1 684 VAL n 
1 685 TRP n 
1 686 PHE n 
1 687 VAL n 
1 688 VAL n 
1 689 ASP n 
1 690 PRO n 
1 691 SER n 
1 692 HIS n 
1 693 SER n 
1 694 VAL n 
1 695 VAL n 
1 696 ASP n 
1 697 PHE n 
1 698 GLN n 
1 699 ASP n 
1 700 GLN n 
1 701 ARG n 
1 702 THR n 
1 703 LEU n 
1 704 ASP n 
1 705 PRO n 
1 706 ARG n 
1 707 PHE n 
1 708 ALA n 
1 709 ARG n 
1 710 GLY n 
1 711 VAL n 
1 712 LEU n 
1 713 LYS n 
1 714 CYS n 
1 715 ASP n 
1 716 ILE n 
1 717 SER n 
1 718 ASP n 
1 719 LEU n 
1 720 SER n 
1 721 LEU n 
1 722 ILE n 
1 723 CYS n 
1 724 LEU n 
1 725 LEU n 
1 726 GLY n 
1 727 TYR n 
1 728 SER n 
1 729 MET n 
1 730 LEU n 
1 731 LEU n 
1 732 MET n 
1 733 VAL n 
1 734 THR n 
1 735 CYS n 
1 736 THR n 
1 737 VAL n 
1 738 TYR n 
1 739 ALA n 
1 740 ILE n 
1 741 LYS n 
1 742 THR n 
1 743 ARG n 
1 744 GLY n 
1 745 VAL n 
1 746 PRO n 
1 747 GLU n 
1 748 THR n 
1 749 PHE n 
1 750 ASN n 
1 751 GLU n 
1 752 ALA n 
1 753 LYS n 
1 754 PRO n 
1 755 ILE n 
1 756 GLY n 
1 757 PHE n 
1 758 THR n 
1 759 MET n 
1 760 TYR n 
1 761 THR n 
1 762 THR n 
1 763 CYS n 
1 764 ILE n 
1 765 VAL n 
1 766 TRP n 
1 767 LEU n 
1 768 ALA n 
1 769 PHE n 
1 770 ILE n 
1 771 PRO n 
1 772 ILE n 
1 773 PHE n 
1 774 PHE n 
1 775 GLY n 
1 776 THR n 
1 777 SER n 
1 778 GLN n 
1 779 SER n 
1 780 ALA n 
1 781 ASP n 
1 782 LYS n 
1 783 LEU n 
1 784 TYR n 
1 785 ILE n 
1 786 GLN n 
1 787 THR n 
1 788 THR n 
1 789 THR n 
1 790 LEU n 
1 791 THR n 
1 792 VAL n 
1 793 SER n 
1 794 VAL n 
1 795 SER n 
1 796 LEU n 
1 797 SER n 
1 798 ALA n 
1 799 SER n 
1 800 VAL n 
1 801 SER n 
1 802 LEU n 
1 803 GLY n 
1 804 MET n 
1 805 LEU n 
1 806 TYR n 
1 807 MET n 
1 808 PRO n 
1 809 LYS n 
1 810 VAL n 
1 811 TYR n 
1 812 ILE n 
1 813 ILE n 
1 814 LEU n 
1 815 PHE n 
1 816 HIS n 
1 817 PRO n 
1 818 GLU n 
1 819 GLN n 
1 820 ASN n 
1 821 VAL n 
1 822 PRO n 
1 823 LYS n 
1 824 ARG n 
1 825 LYS n 
1 826 ARG n 
1 827 SER n 
1 828 LEU n 
1 829 LYS n 
1 830 ALA n 
1 831 VAL n 
1 832 VAL n 
1 833 THR n 
1 834 ALA n 
1 835 ALA n 
1 836 THR n 
1 837 MET n 
1 838 SER n 
1 839 ASN n 
1 840 LYS n 
1 841 PHE n 
1 842 THR n 
1 843 GLN n 
1 844 LYS n 
1 845 GLY n 
1 846 ASN n 
1 847 PHE n 
1 848 ARG n 
1 849 PRO n 
1 850 ASN n 
1 851 GLY n 
1 852 GLU n 
1 853 ALA n 
1 854 LYS n 
1 855 SER n 
1 856 GLU n 
1 857 LEU n 
1 858 CYS n 
1 859 GLU n 
1 860 ASN n 
1 861 LEU n 
1 862 GLU n 
1 863 ALA n 
1 864 PRO n 
1 865 ALA n 
1 866 LEU n 
1 867 ALA n 
1 868 THR n 
1 869 LYS n 
1 870 GLN n 
1 871 THR n 
1 872 TYR n 
1 873 VAL n 
1 874 THR n 
1 875 TYR n 
1 876 THR n 
1 877 ASN n 
1 878 HIS n 
1 879 ALA n 
1 880 ILE n 
2 1   GLU n 
2 2   GLY n 
2 3   PRO n 
2 4   ALA n 
2 5   LYS n 
2 6   LYS n 
2 7   VAL n 
2 8   LEU n 
2 9   THR n 
2 10  LEU n 
2 11  GLU n 
2 12  GLY n 
2 13  ASP n 
2 14  LEU n 
2 15  VAL n 
2 16  LEU n 
2 17  GLY n 
2 18  GLY n 
2 19  LEU n 
2 20  PHE n 
2 21  PRO n 
2 22  VAL n 
2 23  HIS n 
2 24  GLN n 
2 25  LYS n 
2 26  GLY n 
2 27  GLY n 
2 28  PRO n 
2 29  ALA n 
2 30  GLU n 
2 31  ASP n 
2 32  CYS n 
2 33  GLY n 
2 34  PRO n 
2 35  VAL n 
2 36  ASN n 
2 37  GLU n 
2 38  HIS n 
2 39  ARG n 
2 40  GLY n 
2 41  ILE n 
2 42  GLN n 
2 43  ARG n 
2 44  LEU n 
2 45  GLU n 
2 46  ALA n 
2 47  MET n 
2 48  LEU n 
2 49  PHE n 
2 50  ALA n 
2 51  LEU n 
2 52  ASP n 
2 53  ARG n 
2 54  ILE n 
2 55  ASN n 
2 56  ARG n 
2 57  ASP n 
2 58  PRO n 
2 59  HIS n 
2 60  LEU n 
2 61  LEU n 
2 62  PRO n 
2 63  GLY n 
2 64  VAL n 
2 65  ARG n 
2 66  LEU n 
2 67  GLY n 
2 68  ALA n 
2 69  HIS n 
2 70  ILE n 
2 71  LEU n 
2 72  ASP n 
2 73  SER n 
2 74  CYS n 
2 75  SER n 
2 76  LYS n 
2 77  ASP n 
2 78  THR n 
2 79  HIS n 
2 80  ALA n 
2 81  LEU n 
2 82  GLU n 
2 83  GLN n 
2 84  ALA n 
2 85  LEU n 
2 86  ASP n 
2 87  PHE n 
2 88  VAL n 
2 89  ARG n 
2 90  ALA n 
2 91  SER n 
2 92  LEU n 
2 93  SER n 
2 94  ARG n 
2 95  GLY n 
2 96  ALA n 
2 97  ASP n 
2 98  GLY n 
2 99  SER n 
2 100 ARG n 
2 101 HIS n 
2 102 ILE n 
2 103 CYS n 
2 104 PRO n 
2 105 ASP n 
2 106 GLY n 
2 107 SER n 
2 108 TYR n 
2 109 ALA n 
2 110 THR n 
2 111 HIS n 
2 112 GLY n 
2 113 ASP n 
2 114 ALA n 
2 115 PRO n 
2 116 THR n 
2 117 ALA n 
2 118 ILE n 
2 119 THR n 
2 120 GLY n 
2 121 VAL n 
2 122 ILE n 
2 123 GLY n 
2 124 GLY n 
2 125 SER n 
2 126 TYR n 
2 127 SER n 
2 128 ASP n 
2 129 VAL n 
2 130 SER n 
2 131 ILE n 
2 132 GLN n 
2 133 VAL n 
2 134 ALA n 
2 135 ASN n 
2 136 LEU n 
2 137 LEU n 
2 138 ARG n 
2 139 LEU n 
2 140 PHE n 
2 141 GLN n 
2 142 ILE n 
2 143 PRO n 
2 144 GLN n 
2 145 ILE n 
2 146 SER n 
2 147 TYR n 
2 148 ALA n 
2 149 SER n 
2 150 THR n 
2 151 SER n 
2 152 ALA n 
2 153 LYS n 
2 154 LEU n 
2 155 SER n 
2 156 ASP n 
2 157 LYS n 
2 158 SER n 
2 159 ARG n 
2 160 TYR n 
2 161 ASP n 
2 162 TYR n 
2 163 PHE n 
2 164 ALA n 
2 165 ARG n 
2 166 THR n 
2 167 VAL n 
2 168 PRO n 
2 169 PRO n 
2 170 ASP n 
2 171 PHE n 
2 172 PHE n 
2 173 GLN n 
2 174 ALA n 
2 175 LYS n 
2 176 ALA n 
2 177 MET n 
2 178 ALA n 
2 179 GLU n 
2 180 ILE n 
2 181 LEU n 
2 182 ARG n 
2 183 PHE n 
2 184 PHE n 
2 185 ASN n 
2 186 TRP n 
2 187 THR n 
2 188 TYR n 
2 189 VAL n 
2 190 SER n 
2 191 THR n 
2 192 VAL n 
2 193 ALA n 
2 194 SER n 
2 195 GLU n 
2 196 GLY n 
2 197 ASP n 
2 198 TYR n 
2 199 GLY n 
2 200 GLU n 
2 201 THR n 
2 202 GLY n 
2 203 ILE n 
2 204 GLU n 
2 205 ALA n 
2 206 PHE n 
2 207 GLU n 
2 208 LEU n 
2 209 GLU n 
2 210 ALA n 
2 211 ARG n 
2 212 ALA n 
2 213 ARG n 
2 214 ASN n 
2 215 ILE n 
2 216 CYS n 
2 217 VAL n 
2 218 ALA n 
2 219 THR n 
2 220 SER n 
2 221 GLU n 
2 222 LYS n 
2 223 VAL n 
2 224 GLY n 
2 225 ARG n 
2 226 ALA n 
2 227 MET n 
2 228 SER n 
2 229 ARG n 
2 230 ALA n 
2 231 ALA n 
2 232 PHE n 
2 233 GLU n 
2 234 GLY n 
2 235 VAL n 
2 236 VAL n 
2 237 ARG n 
2 238 ALA n 
2 239 LEU n 
2 240 LEU n 
2 241 GLN n 
2 242 LYS n 
2 243 PRO n 
2 244 SER n 
2 245 ALA n 
2 246 ARG n 
2 247 VAL n 
2 248 ALA n 
2 249 VAL n 
2 250 LEU n 
2 251 PHE n 
2 252 THR n 
2 253 ARG n 
2 254 SER n 
2 255 GLU n 
2 256 ASP n 
2 257 ALA n 
2 258 ARG n 
2 259 GLU n 
2 260 LEU n 
2 261 LEU n 
2 262 ALA n 
2 263 ALA n 
2 264 SER n 
2 265 GLN n 
2 266 ARG n 
2 267 LEU n 
2 268 ASN n 
2 269 ALA n 
2 270 SER n 
2 271 PHE n 
2 272 THR n 
2 273 TRP n 
2 274 VAL n 
2 275 ALA n 
2 276 SER n 
2 277 ASP n 
2 278 GLY n 
2 279 TRP n 
2 280 GLY n 
2 281 ALA n 
2 282 LEU n 
2 283 GLU n 
2 284 SER n 
2 285 VAL n 
2 286 VAL n 
2 287 ALA n 
2 288 GLY n 
2 289 SER n 
2 290 GLU n 
2 291 GLY n 
2 292 ALA n 
2 293 ALA n 
2 294 GLU n 
2 295 GLY n 
2 296 ALA n 
2 297 ILE n 
2 298 THR n 
2 299 ILE n 
2 300 GLU n 
2 301 LEU n 
2 302 ALA n 
2 303 SER n 
2 304 TYR n 
2 305 PRO n 
2 306 ILE n 
2 307 SER n 
2 308 ASP n 
2 309 PHE n 
2 310 ALA n 
2 311 SER n 
2 312 TYR n 
2 313 PHE n 
2 314 GLN n 
2 315 SER n 
2 316 LEU n 
2 317 ASP n 
2 318 PRO n 
2 319 TRP n 
2 320 ASN n 
2 321 ASN n 
2 322 SER n 
2 323 ARG n 
2 324 ASN n 
2 325 PRO n 
2 326 TRP n 
2 327 PHE n 
2 328 ARG n 
2 329 GLU n 
2 330 PHE n 
2 331 TRP n 
2 332 GLU n 
2 333 GLN n 
2 334 ARG n 
2 335 PHE n 
2 336 ARG n 
2 337 CYS n 
2 338 SER n 
2 339 PHE n 
2 340 ARG n 
2 341 GLN n 
2 342 ARG n 
2 343 ASP n 
2 344 CYS n 
2 345 ALA n 
2 346 ALA n 
2 347 HIS n 
2 348 SER n 
2 349 LEU n 
2 350 ARG n 
2 351 ALA n 
2 352 VAL n 
2 353 PRO n 
2 354 PHE n 
2 355 GLU n 
2 356 GLN n 
2 357 GLU n 
2 358 SER n 
2 359 LYS n 
2 360 ILE n 
2 361 MET n 
2 362 PHE n 
2 363 VAL n 
2 364 VAL n 
2 365 ASN n 
2 366 ALA n 
2 367 VAL n 
2 368 TYR n 
2 369 ALA n 
2 370 MET n 
2 371 ALA n 
2 372 HIS n 
2 373 ALA n 
2 374 LEU n 
2 375 HIS n 
2 376 ASN n 
2 377 MET n 
2 378 HIS n 
2 379 ARG n 
2 380 ALA n 
2 381 LEU n 
2 382 CYS n 
2 383 PRO n 
2 384 ASN n 
2 385 THR n 
2 386 THR n 
2 387 ARG n 
2 388 LEU n 
2 389 CYS n 
2 390 ASP n 
2 391 ALA n 
2 392 MET n 
2 393 ARG n 
2 394 PRO n 
2 395 VAL n 
2 396 ASN n 
2 397 GLY n 
2 398 ARG n 
2 399 ARG n 
2 400 LEU n 
2 401 TYR n 
2 402 LYS n 
2 403 ASP n 
2 404 PHE n 
2 405 VAL n 
2 406 LEU n 
2 407 ASN n 
2 408 VAL n 
2 409 LYS n 
2 410 PHE n 
2 411 ASP n 
2 412 ALA n 
2 413 PRO n 
2 414 PHE n 
2 415 ARG n 
2 416 PRO n 
2 417 ALA n 
2 418 ASP n 
2 419 THR n 
2 420 HIS n 
2 421 ASN n 
2 422 GLU n 
2 423 VAL n 
2 424 ARG n 
2 425 PHE n 
2 426 ASP n 
2 427 ARG n 
2 428 PHE n 
2 429 GLY n 
2 430 ASP n 
2 431 GLY n 
2 432 ILE n 
2 433 GLY n 
2 434 ARG n 
2 435 TYR n 
2 436 ASN n 
2 437 ILE n 
2 438 PHE n 
2 439 THR n 
2 440 TYR n 
2 441 LEU n 
2 442 ARG n 
2 443 ALA n 
2 444 GLY n 
2 445 SER n 
2 446 GLY n 
2 447 ARG n 
2 448 TYR n 
2 449 ARG n 
2 450 TYR n 
2 451 GLN n 
2 452 LYS n 
2 453 VAL n 
2 454 GLY n 
2 455 TYR n 
2 456 TRP n 
2 457 ALA n 
2 458 GLU n 
2 459 GLY n 
2 460 LEU n 
2 461 THR n 
2 462 LEU n 
2 463 ASP n 
2 464 THR n 
2 465 SER n 
2 466 LEU n 
2 467 ILE n 
2 468 PRO n 
2 469 TRP n 
2 470 ALA n 
2 471 SER n 
2 472 PRO n 
2 473 SER n 
2 474 ALA n 
2 475 GLY n 
2 476 PRO n 
2 477 LEU n 
2 478 PRO n 
2 479 ALA n 
2 480 SER n 
2 481 ARG n 
2 482 CYS n 
2 483 SER n 
2 484 GLU n 
2 485 PRO n 
2 486 CYS n 
2 487 LEU n 
2 488 GLN n 
2 489 ASN n 
2 490 GLU n 
2 491 VAL n 
2 492 LYS n 
2 493 SER n 
2 494 VAL n 
2 495 GLN n 
2 496 PRO n 
2 497 GLY n 
2 498 GLU n 
2 499 VAL n 
2 500 CYS n 
2 501 CYS n 
2 502 TRP n 
2 503 LEU n 
2 504 CYS n 
2 505 ILE n 
2 506 PRO n 
2 507 CYS n 
2 508 GLN n 
2 509 PRO n 
2 510 TYR n 
2 511 GLU n 
2 512 TYR n 
2 513 ARG n 
2 514 LEU n 
2 515 ASP n 
2 516 GLU n 
2 517 PHE n 
2 518 THR n 
2 519 CYS n 
2 520 ALA n 
2 521 ASP n 
2 522 CYS n 
2 523 GLY n 
2 524 LEU n 
2 525 GLY n 
2 526 TYR n 
2 527 TRP n 
2 528 PRO n 
2 529 ASN n 
2 530 ALA n 
2 531 SER n 
2 532 LEU n 
2 533 THR n 
2 534 GLY n 
2 535 CYS n 
2 536 PHE n 
2 537 GLU n 
2 538 LEU n 
2 539 PRO n 
2 540 GLN n 
2 541 GLU n 
2 542 TYR n 
2 543 ILE n 
2 544 ARG n 
2 545 TRP n 
2 546 GLY n 
2 547 ASP n 
2 548 ALA n 
2 549 TRP n 
2 550 ALA n 
2 551 VAL n 
2 552 GLY n 
2 553 PRO n 
2 554 VAL n 
2 555 THR n 
2 556 ILE n 
2 557 ALA n 
2 558 CYS n 
2 559 LEU n 
2 560 GLY n 
2 561 ALA n 
2 562 LEU n 
2 563 ALA n 
2 564 THR n 
2 565 LEU n 
2 566 PHE n 
2 567 VAL n 
2 568 LEU n 
2 569 GLY n 
2 570 VAL n 
2 571 PHE n 
2 572 VAL n 
2 573 ARG n 
2 574 HIS n 
2 575 ASN n 
2 576 ALA n 
2 577 THR n 
2 578 PRO n 
2 579 VAL n 
2 580 VAL n 
2 581 LYS n 
2 582 ALA n 
2 583 SER n 
2 584 GLY n 
2 585 ARG n 
2 586 GLU n 
2 587 LEU n 
2 588 CYS n 
2 589 TYR n 
2 590 ILE n 
2 591 LEU n 
2 592 LEU n 
2 593 GLY n 
2 594 GLY n 
2 595 VAL n 
2 596 PHE n 
2 597 LEU n 
2 598 CYS n 
2 599 TYR n 
2 600 CYS n 
2 601 MET n 
2 602 THR n 
2 603 PHE n 
2 604 ILE n 
2 605 PHE n 
2 606 ILE n 
2 607 ALA n 
2 608 LYS n 
2 609 PRO n 
2 610 SER n 
2 611 THR n 
2 612 ALA n 
2 613 VAL n 
2 614 CYS n 
2 615 THR n 
2 616 LEU n 
2 617 ARG n 
2 618 ARG n 
2 619 LEU n 
2 620 GLY n 
2 621 LEU n 
2 622 GLY n 
2 623 THR n 
2 624 ALA n 
2 625 PHE n 
2 626 SER n 
2 627 VAL n 
2 628 CYS n 
2 629 TYR n 
2 630 SER n 
2 631 ALA n 
2 632 LEU n 
2 633 LEU n 
2 634 THR n 
2 635 LYS n 
2 636 THR n 
2 637 ASN n 
2 638 ARG n 
2 639 ILE n 
2 640 ALA n 
2 641 ARG n 
2 642 ILE n 
2 643 PHE n 
2 644 GLY n 
2 645 GLY n 
2 646 ALA n 
2 647 ARG n 
2 648 GLU n 
2 649 GLY n 
2 650 ALA n 
2 651 GLN n 
2 652 ARG n 
2 653 PRO n 
2 654 ARG n 
2 655 PHE n 
2 656 ILE n 
2 657 SER n 
2 658 PRO n 
2 659 ALA n 
2 660 SER n 
2 661 GLN n 
2 662 VAL n 
2 663 ALA n 
2 664 ILE n 
2 665 CYS n 
2 666 LEU n 
2 667 ALA n 
2 668 LEU n 
2 669 ILE n 
2 670 SER n 
2 671 GLY n 
2 672 GLN n 
2 673 LEU n 
2 674 LEU n 
2 675 ILE n 
2 676 VAL n 
2 677 VAL n 
2 678 ALA n 
2 679 TRP n 
2 680 LEU n 
2 681 VAL n 
2 682 VAL n 
2 683 GLU n 
2 684 ALA n 
2 685 PRO n 
2 686 GLY n 
2 687 THR n 
2 688 GLY n 
2 689 LYS n 
2 690 GLU n 
2 691 THR n 
2 692 ALA n 
2 693 PRO n 
2 694 GLU n 
2 695 ARG n 
2 696 ARG n 
2 697 GLU n 
2 698 VAL n 
2 699 VAL n 
2 700 THR n 
2 701 LEU n 
2 702 ARG n 
2 703 CYS n 
2 704 ASN n 
2 705 HIS n 
2 706 ARG n 
2 707 ASP n 
2 708 ALA n 
2 709 SER n 
2 710 MET n 
2 711 LEU n 
2 712 GLY n 
2 713 SER n 
2 714 LEU n 
2 715 ALA n 
2 716 TYR n 
2 717 ASN n 
2 718 VAL n 
2 719 LEU n 
2 720 LEU n 
2 721 ILE n 
2 722 ALA n 
2 723 LEU n 
2 724 CYS n 
2 725 THR n 
2 726 LEU n 
2 727 TYR n 
2 728 ALA n 
2 729 PHE n 
2 730 LYS n 
2 731 THR n 
2 732 ARG n 
2 733 LYS n 
2 734 CYS n 
2 735 PRO n 
2 736 GLU n 
2 737 ASN n 
2 738 PHE n 
2 739 ASN n 
2 740 GLU n 
2 741 ALA n 
2 742 LYS n 
2 743 PHE n 
2 744 ILE n 
2 745 GLY n 
2 746 PHE n 
2 747 THR n 
2 748 MET n 
2 749 TYR n 
2 750 THR n 
2 751 THR n 
2 752 CYS n 
2 753 ILE n 
2 754 ILE n 
2 755 TRP n 
2 756 LEU n 
2 757 ALA n 
2 758 PHE n 
2 759 LEU n 
2 760 PRO n 
2 761 ILE n 
2 762 PHE n 
2 763 TYR n 
2 764 VAL n 
2 765 THR n 
2 766 SER n 
2 767 SER n 
2 768 ASP n 
2 769 TYR n 
2 770 ARG n 
2 771 VAL n 
2 772 GLN n 
2 773 THR n 
2 774 THR n 
2 775 THR n 
2 776 MET n 
2 777 CYS n 
2 778 VAL n 
2 779 SER n 
2 780 VAL n 
2 781 SER n 
2 782 LEU n 
2 783 SER n 
2 784 GLY n 
2 785 SER n 
2 786 VAL n 
2 787 VAL n 
2 788 LEU n 
2 789 GLY n 
2 790 CYS n 
2 791 LEU n 
2 792 PHE n 
2 793 ALA n 
2 794 PRO n 
2 795 LYS n 
2 796 LEU n 
2 797 HIS n 
2 798 ILE n 
2 799 ILE n 
2 800 LEU n 
2 801 PHE n 
2 802 GLN n 
2 803 PRO n 
2 804 GLN n 
2 805 LYS n 
2 806 ASN n 
2 807 VAL n 
2 808 VAL n 
2 809 SER n 
2 810 HIS n 
2 811 ARG n 
2 812 ALA n 
2 813 PRO n 
2 814 THR n 
2 815 SER n 
2 816 ARG n 
2 817 PHE n 
2 818 GLY n 
2 819 SER n 
2 820 ALA n 
2 821 ALA n 
2 822 ALA n 
2 823 ARG n 
2 824 ALA n 
2 825 SER n 
2 826 SER n 
2 827 SER n 
2 828 LEU n 
2 829 GLY n 
2 830 GLN n 
2 831 GLY n 
2 832 SER n 
2 833 GLY n 
2 834 SER n 
2 835 GLN n 
2 836 PHE n 
2 837 VAL n 
2 838 PRO n 
2 839 THR n 
2 840 VAL n 
2 841 CYS n 
2 842 ASN n 
2 843 GLY n 
2 844 ARG n 
2 845 GLU n 
2 846 VAL n 
2 847 VAL n 
2 848 ASP n 
2 849 SER n 
2 850 THR n 
2 851 THR n 
2 852 SER n 
2 853 SER n 
2 854 LEU n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 880 human ? GRM4 ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Spodoptera frugiperda' 7108 ? 
? ? ? ? ? ? ? ?      ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 854 human ? GRM2 ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Homo sapiens'          9606 ? 
? ? ? ? ? ? ? HEK293 ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                                 ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE                                ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE                              ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                         ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE                                ? 'C3 H7 N O2 S'   121.158 
E7P non-polymer         . '(2S)-2-amino-4-phosphonobutanoic acid' ? 'C4 H10 N O5 P'  183.100 
GLN 'L-peptide linking' y GLUTAMINE                               ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                         ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE                                 ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE                               ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE                              ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE                                 ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE                                  ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE                              ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE                           ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE                                 ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE                                  ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE                               ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                              ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE                                ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE                                  ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   LYS 1   33  ?   ?   ?   B . n 
A 1 2   PRO 2   34  ?   ?   ?   B . n 
A 1 3   LYS 3   35  ?   ?   ?   B . n 
A 1 4   GLY 4   36  ?   ?   ?   B . n 
A 1 5   HIS 5   37  ?   ?   ?   B . n 
A 1 6   PRO 6   38  ?   ?   ?   B . n 
A 1 7   HIS 7   39  ?   ?   ?   B . n 
A 1 8   MET 8   40  ?   ?   ?   B . n 
A 1 9   ASN 9   41  41  ASN ASN B . n 
A 1 10  SER 10  42  42  SER SER B . n 
A 1 11  ILE 11  43  43  ILE ILE B . n 
A 1 12  ARG 12  44  44  ARG ARG B . n 
A 1 13  ILE 13  45  45  ILE ILE B . n 
A 1 14  ASP 14  46  46  ASP ASP B . n 
A 1 15  GLY 15  47  47  GLY GLY B . n 
A 1 16  ASP 16  48  48  ASP ASP B . n 
A 1 17  ILE 17  49  49  ILE ILE B . n 
A 1 18  THR 18  50  50  THR THR B . n 
A 1 19  LEU 19  51  51  LEU LEU B . n 
A 1 20  GLY 20  52  52  GLY GLY B . n 
A 1 21  GLY 21  53  53  GLY GLY B . n 
A 1 22  LEU 22  54  54  LEU LEU B . n 
A 1 23  PHE 23  55  55  PHE PHE B . n 
A 1 24  PRO 24  56  56  PRO PRO B . n 
A 1 25  VAL 25  57  57  VAL VAL B . n 
A 1 26  HIS 26  58  58  HIS HIS B . n 
A 1 27  GLY 27  59  59  GLY GLY B . n 
A 1 28  ARG 28  60  60  ARG ARG B . n 
A 1 29  GLY 29  61  61  GLY GLY B . n 
A 1 30  SER 30  62  62  SER SER B . n 
A 1 31  GLU 31  63  63  GLU GLU B . n 
A 1 32  GLY 32  64  64  GLY GLY B . n 
A 1 33  LYS 33  65  65  LYS LYS B . n 
A 1 34  PRO 34  66  66  PRO PRO B . n 
A 1 35  CYS 35  67  67  CYS CYS B . n 
A 1 36  GLY 36  68  68  GLY GLY B . n 
A 1 37  GLU 37  69  69  GLU GLU B . n 
A 1 38  LEU 38  70  70  LEU LEU B . n 
A 1 39  LYS 39  71  71  LYS LYS B . n 
A 1 40  LYS 40  72  72  LYS LYS B . n 
A 1 41  GLU 41  73  73  GLU GLU B . n 
A 1 42  LYS 42  74  74  LYS LYS B . n 
A 1 43  GLY 43  75  75  GLY GLY B . n 
A 1 44  ILE 44  76  76  ILE ILE B . n 
A 1 45  HIS 45  77  77  HIS HIS B . n 
A 1 46  ARG 46  78  78  ARG ARG B . n 
A 1 47  LEU 47  79  79  LEU LEU B . n 
A 1 48  GLU 48  80  80  GLU GLU B . n 
A 1 49  ALA 49  81  81  ALA ALA B . n 
A 1 50  MET 50  82  82  MET MET B . n 
A 1 51  LEU 51  83  83  LEU LEU B . n 
A 1 52  PHE 52  84  84  PHE PHE B . n 
A 1 53  ALA 53  85  85  ALA ALA B . n 
A 1 54  LEU 54  86  86  LEU LEU B . n 
A 1 55  ASP 55  87  87  ASP ASP B . n 
A 1 56  ARG 56  88  88  ARG ARG B . n 
A 1 57  ILE 57  89  89  ILE ILE B . n 
A 1 58  ASN 58  90  90  ASN ASN B . n 
A 1 59  ASN 59  91  91  ASN ASN B . n 
A 1 60  ASP 60  92  92  ASP ASP B . n 
A 1 61  PRO 61  93  93  PRO PRO B . n 
A 1 62  ASP 62  94  94  ASP ASP B . n 
A 1 63  LEU 63  95  95  LEU LEU B . n 
A 1 64  LEU 64  96  96  LEU LEU B . n 
A 1 65  PRO 65  97  97  PRO PRO B . n 
A 1 66  ASN 66  98  98  ASN ASN B . n 
A 1 67  ILE 67  99  99  ILE ILE B . n 
A 1 68  THR 68  100 100 THR THR B . n 
A 1 69  LEU 69  101 101 LEU LEU B . n 
A 1 70  GLY 70  102 102 GLY GLY B . n 
A 1 71  ALA 71  103 103 ALA ALA B . n 
A 1 72  ARG 72  104 104 ARG ARG B . n 
A 1 73  ILE 73  105 105 ILE ILE B . n 
A 1 74  LEU 74  106 106 LEU LEU B . n 
A 1 75  ASP 75  107 107 ASP ASP B . n 
A 1 76  THR 76  108 108 THR THR B . n 
A 1 77  CYS 77  109 109 CYS CYS B . n 
A 1 78  SER 78  110 110 SER SER B . n 
A 1 79  ARG 79  111 111 ARG ARG B . n 
A 1 80  ASP 80  112 112 ASP ASP B . n 
A 1 81  THR 81  113 113 THR THR B . n 
A 1 82  HIS 82  114 114 HIS HIS B . n 
A 1 83  ALA 83  115 115 ALA ALA B . n 
A 1 84  LEU 84  116 116 LEU LEU B . n 
A 1 85  GLU 85  117 117 GLU GLU B . n 
A 1 86  GLN 86  118 118 GLN GLN B . n 
A 1 87  SER 87  119 119 SER SER B . n 
A 1 88  LEU 88  120 120 LEU LEU B . n 
A 1 89  THR 89  121 121 THR THR B . n 
A 1 90  PHE 90  122 122 PHE PHE B . n 
A 1 91  VAL 91  123 123 VAL VAL B . n 
A 1 92  GLN 92  124 124 GLN GLN B . n 
A 1 93  ALA 93  125 125 ALA ALA B . n 
A 1 94  LEU 94  126 126 LEU LEU B . n 
A 1 95  ILE 95  127 127 ILE ILE B . n 
A 1 96  GLU 96  128 ?   ?   ?   B . n 
A 1 97  LYS 97  129 ?   ?   ?   B . n 
A 1 98  ASP 98  130 ?   ?   ?   B . n 
A 1 99  GLY 99  131 ?   ?   ?   B . n 
A 1 100 THR 100 132 ?   ?   ?   B . n 
A 1 101 GLU 101 133 ?   ?   ?   B . n 
A 1 102 VAL 102 134 ?   ?   ?   B . n 
A 1 103 ARG 103 135 ?   ?   ?   B . n 
A 1 104 CYS 104 136 ?   ?   ?   B . n 
A 1 105 GLY 105 137 ?   ?   ?   B . n 
A 1 106 SER 106 138 ?   ?   ?   B . n 
A 1 107 GLY 107 139 ?   ?   ?   B . n 
A 1 108 GLY 108 140 ?   ?   ?   B . n 
A 1 109 PRO 109 141 ?   ?   ?   B . n 
A 1 110 PRO 110 142 ?   ?   ?   B . n 
A 1 111 ILE 111 143 ?   ?   ?   B . n 
A 1 112 ILE 112 144 ?   ?   ?   B . n 
A 1 113 THR 113 145 ?   ?   ?   B . n 
A 1 114 LYS 114 146 ?   ?   ?   B . n 
A 1 115 PRO 115 147 ?   ?   ?   B . n 
A 1 116 GLU 116 148 148 GLU GLU B . n 
A 1 117 ARG 117 149 149 ARG ARG B . n 
A 1 118 VAL 118 150 150 VAL VAL B . n 
A 1 119 VAL 119 151 151 VAL VAL B . n 
A 1 120 GLY 120 152 152 GLY GLY B . n 
A 1 121 VAL 121 153 153 VAL VAL B . n 
A 1 122 ILE 122 154 154 ILE ILE B . n 
A 1 123 GLY 123 155 155 GLY GLY B . n 
A 1 124 ALA 124 156 156 ALA ALA B . n 
A 1 125 SER 125 157 157 SER SER B . n 
A 1 126 GLY 126 158 158 GLY GLY B . n 
A 1 127 SER 127 159 159 SER SER B . n 
A 1 128 SER 128 160 160 SER SER B . n 
A 1 129 VAL 129 161 161 VAL VAL B . n 
A 1 130 SER 130 162 162 SER SER B . n 
A 1 131 ILE 131 163 163 ILE ILE B . n 
A 1 132 MET 132 164 164 MET MET B . n 
A 1 133 VAL 133 165 165 VAL VAL B . n 
A 1 134 ALA 134 166 166 ALA ALA B . n 
A 1 135 ASN 135 167 167 ASN ASN B . n 
A 1 136 ILE 136 168 168 ILE ILE B . n 
A 1 137 LEU 137 169 169 LEU LEU B . n 
A 1 138 ARG 138 170 170 ARG ARG B . n 
A 1 139 LEU 139 171 171 LEU LEU B . n 
A 1 140 PHE 140 172 172 PHE PHE B . n 
A 1 141 LYS 141 173 173 LYS LYS B . n 
A 1 142 ILE 142 174 174 ILE ILE B . n 
A 1 143 PRO 143 175 175 PRO PRO B . n 
A 1 144 GLN 144 176 176 GLN GLN B . n 
A 1 145 ILE 145 177 177 ILE ILE B . n 
A 1 146 SER 146 178 178 SER SER B . n 
A 1 147 TYR 147 179 179 TYR TYR B . n 
A 1 148 ALA 148 180 180 ALA ALA B . n 
A 1 149 SER 149 181 181 SER SER B . n 
A 1 150 THR 150 182 182 THR THR B . n 
A 1 151 ALA 151 183 183 ALA ALA B . n 
A 1 152 PRO 152 184 184 PRO PRO B . n 
A 1 153 ASP 153 185 185 ASP ASP B . n 
A 1 154 LEU 154 186 186 LEU LEU B . n 
A 1 155 SER 155 187 187 SER SER B . n 
A 1 156 ASP 156 188 188 ASP ASP B . n 
A 1 157 ASN 157 189 189 ASN ASN B . n 
A 1 158 SER 158 190 190 SER SER B . n 
A 1 159 ARG 159 191 191 ARG ARG B . n 
A 1 160 TYR 160 192 192 TYR TYR B . n 
A 1 161 ASP 161 193 193 ASP ASP B . n 
A 1 162 PHE 162 194 194 PHE PHE B . n 
A 1 163 PHE 163 195 195 PHE PHE B . n 
A 1 164 SER 164 196 196 SER SER B . n 
A 1 165 ARG 165 197 197 ARG ARG B . n 
A 1 166 VAL 166 198 198 VAL VAL B . n 
A 1 167 VAL 167 199 199 VAL VAL B . n 
A 1 168 PRO 168 200 200 PRO PRO B . n 
A 1 169 SER 169 201 201 SER SER B . n 
A 1 170 ASP 170 202 202 ASP ASP B . n 
A 1 171 THR 171 203 203 THR THR B . n 
A 1 172 TYR 172 204 204 TYR TYR B . n 
A 1 173 GLN 173 205 205 GLN GLN B . n 
A 1 174 ALA 174 206 206 ALA ALA B . n 
A 1 175 GLN 175 207 207 GLN GLN B . n 
A 1 176 ALA 176 208 208 ALA ALA B . n 
A 1 177 MET 177 209 209 MET MET B . n 
A 1 178 VAL 178 210 210 VAL VAL B . n 
A 1 179 ASP 179 211 211 ASP ASP B . n 
A 1 180 ILE 180 212 212 ILE ILE B . n 
A 1 181 VAL 181 213 213 VAL VAL B . n 
A 1 182 ARG 182 214 214 ARG ARG B . n 
A 1 183 ALA 183 215 215 ALA ALA B . n 
A 1 184 LEU 184 216 216 LEU LEU B . n 
A 1 185 LYS 185 217 217 LYS LYS B . n 
A 1 186 TRP 186 218 218 TRP TRP B . n 
A 1 187 ASN 187 219 219 ASN ASN B . n 
A 1 188 TYR 188 220 220 TYR TYR B . n 
A 1 189 VAL 189 221 221 VAL VAL B . n 
A 1 190 SER 190 222 222 SER SER B . n 
A 1 191 THR 191 223 223 THR THR B . n 
A 1 192 VAL 192 224 224 VAL VAL B . n 
A 1 193 ALA 193 225 225 ALA ALA B . n 
A 1 194 SER 194 226 226 SER SER B . n 
A 1 195 GLU 195 227 227 GLU GLU B . n 
A 1 196 GLY 196 228 228 GLY GLY B . n 
A 1 197 SER 197 229 229 SER SER B . n 
A 1 198 TYR 198 230 230 TYR TYR B . n 
A 1 199 GLY 199 231 231 GLY GLY B . n 
A 1 200 GLU 200 232 232 GLU GLU B . n 
A 1 201 SER 201 233 233 SER SER B . n 
A 1 202 GLY 202 234 234 GLY GLY B . n 
A 1 203 VAL 203 235 235 VAL VAL B . n 
A 1 204 GLU 204 236 236 GLU GLU B . n 
A 1 205 ALA 205 237 237 ALA ALA B . n 
A 1 206 PHE 206 238 238 PHE PHE B . n 
A 1 207 ILE 207 239 239 ILE ILE B . n 
A 1 208 GLN 208 240 240 GLN GLN B . n 
A 1 209 LYS 209 241 241 LYS LYS B . n 
A 1 210 SER 210 242 242 SER SER B . n 
A 1 211 ARG 211 243 243 ARG ARG B . n 
A 1 212 GLU 212 244 244 GLU GLU B . n 
A 1 213 ASP 213 245 245 ASP ASP B . n 
A 1 214 GLY 214 246 246 GLY GLY B . n 
A 1 215 GLY 215 247 247 GLY GLY B . n 
A 1 216 VAL 216 248 248 VAL VAL B . n 
A 1 217 CYS 217 249 249 CYS CYS B . n 
A 1 218 ILE 218 250 250 ILE ILE B . n 
A 1 219 ALA 219 251 251 ALA ALA B . n 
A 1 220 GLN 220 252 252 GLN GLN B . n 
A 1 221 SER 221 253 253 SER SER B . n 
A 1 222 VAL 222 254 254 VAL VAL B . n 
A 1 223 LYS 223 255 255 LYS LYS B . n 
A 1 224 ILE 224 256 256 ILE ILE B . n 
A 1 225 PRO 225 257 257 PRO PRO B . n 
A 1 226 ARG 226 258 258 ARG ARG B . n 
A 1 227 GLU 227 259 259 GLU GLU B . n 
A 1 228 PRO 228 260 260 PRO PRO B . n 
A 1 229 LYS 229 261 261 LYS LYS B . n 
A 1 230 ALA 230 262 262 ALA ALA B . n 
A 1 231 GLY 231 263 263 GLY GLY B . n 
A 1 232 GLU 232 264 264 GLU GLU B . n 
A 1 233 PHE 233 265 265 PHE PHE B . n 
A 1 234 ASP 234 266 266 ASP ASP B . n 
A 1 235 LYS 235 267 267 LYS LYS B . n 
A 1 236 ILE 236 268 268 ILE ILE B . n 
A 1 237 ILE 237 269 269 ILE ILE B . n 
A 1 238 ARG 238 270 270 ARG ARG B . n 
A 1 239 ARG 239 271 271 ARG ARG B . n 
A 1 240 LEU 240 272 272 LEU LEU B . n 
A 1 241 LEU 241 273 273 LEU LEU B . n 
A 1 242 GLU 242 274 274 GLU GLU B . n 
A 1 243 THR 243 275 275 THR THR B . n 
A 1 244 SER 244 276 276 SER SER B . n 
A 1 245 ASN 245 277 277 ASN ASN B . n 
A 1 246 ALA 246 278 278 ALA ALA B . n 
A 1 247 ARG 247 279 279 ARG ARG B . n 
A 1 248 ALA 248 280 280 ALA ALA B . n 
A 1 249 VAL 249 281 281 VAL VAL B . n 
A 1 250 ILE 250 282 282 ILE ILE B . n 
A 1 251 ILE 251 283 283 ILE ILE B . n 
A 1 252 PHE 252 284 284 PHE PHE B . n 
A 1 253 ALA 253 285 285 ALA ALA B . n 
A 1 254 ASN 254 286 286 ASN ASN B . n 
A 1 255 GLU 255 287 287 GLU GLU B . n 
A 1 256 ASP 256 288 288 ASP ASP B . n 
A 1 257 ASP 257 289 289 ASP ASP B . n 
A 1 258 ILE 258 290 290 ILE ILE B . n 
A 1 259 ARG 259 291 291 ARG ARG B . n 
A 1 260 ARG 260 292 292 ARG ARG B . n 
A 1 261 VAL 261 293 293 VAL VAL B . n 
A 1 262 LEU 262 294 294 LEU LEU B . n 
A 1 263 GLU 263 295 295 GLU GLU B . n 
A 1 264 ALA 264 296 296 ALA ALA B . n 
A 1 265 ALA 265 297 297 ALA ALA B . n 
A 1 266 ARG 266 298 298 ARG ARG B . n 
A 1 267 ARG 267 299 299 ARG ARG B . n 
A 1 268 ALA 268 300 300 ALA ALA B . n 
A 1 269 ASN 269 301 301 ASN ASN B . n 
A 1 270 GLN 270 302 302 GLN GLN B . n 
A 1 271 THR 271 303 303 THR THR B . n 
A 1 272 GLY 272 304 304 GLY GLY B . n 
A 1 273 HIS 273 305 305 HIS HIS B . n 
A 1 274 PHE 274 306 306 PHE PHE B . n 
A 1 275 PHE 275 307 307 PHE PHE B . n 
A 1 276 TRP 276 308 308 TRP TRP B . n 
A 1 277 MET 277 309 309 MET MET B . n 
A 1 278 GLY 278 310 310 GLY GLY B . n 
A 1 279 SER 279 311 311 SER SER B . n 
A 1 280 ASP 280 312 312 ASP ASP B . n 
A 1 281 SER 281 313 313 SER SER B . n 
A 1 282 TRP 282 314 314 TRP TRP B . n 
A 1 283 GLY 283 315 315 GLY GLY B . n 
A 1 284 SER 284 316 316 SER SER B . n 
A 1 285 LYS 285 317 317 LYS LYS B . n 
A 1 286 ILE 286 318 318 ILE ILE B . n 
A 1 287 ALA 287 319 319 ALA ALA B . n 
A 1 288 PRO 288 320 320 PRO PRO B . n 
A 1 289 VAL 289 321 321 VAL VAL B . n 
A 1 290 LEU 290 322 322 LEU LEU B . n 
A 1 291 HIS 291 323 323 HIS HIS B . n 
A 1 292 LEU 292 324 324 LEU LEU B . n 
A 1 293 GLU 293 325 325 GLU GLU B . n 
A 1 294 GLU 294 326 326 GLU GLU B . n 
A 1 295 VAL 295 327 327 VAL VAL B . n 
A 1 296 ALA 296 328 328 ALA ALA B . n 
A 1 297 GLU 297 329 329 GLU GLU B . n 
A 1 298 GLY 298 330 330 GLY GLY B . n 
A 1 299 ALA 299 331 331 ALA ALA B . n 
A 1 300 VAL 300 332 332 VAL VAL B . n 
A 1 301 THR 301 333 333 THR THR B . n 
A 1 302 ILE 302 334 334 ILE ILE B . n 
A 1 303 LEU 303 335 335 LEU LEU B . n 
A 1 304 PRO 304 336 336 PRO PRO B . n 
A 1 305 LYS 305 337 337 LYS LYS B . n 
A 1 306 ARG 306 338 338 ARG ARG B . n 
A 1 307 MET 307 339 339 MET MET B . n 
A 1 308 SER 308 340 340 SER SER B . n 
A 1 309 VAL 309 341 341 VAL VAL B . n 
A 1 310 ARG 310 342 342 ARG ARG B . n 
A 1 311 GLY 311 343 343 GLY GLY B . n 
A 1 312 PHE 312 344 344 PHE PHE B . n 
A 1 313 ASP 313 345 345 ASP ASP B . n 
A 1 314 ARG 314 346 346 ARG ARG B . n 
A 1 315 TYR 315 347 347 TYR TYR B . n 
A 1 316 PHE 316 348 348 PHE PHE B . n 
A 1 317 SER 317 349 349 SER SER B . n 
A 1 318 SER 318 350 350 SER SER B . n 
A 1 319 ARG 319 351 351 ARG ARG B . n 
A 1 320 THR 320 352 352 THR THR B . n 
A 1 321 LEU 321 353 353 LEU LEU B . n 
A 1 322 ASP 322 354 354 ASP ASP B . n 
A 1 323 ASN 323 355 355 ASN ASN B . n 
A 1 324 ASN 324 356 356 ASN ASN B . n 
A 1 325 ARG 325 357 357 ARG ARG B . n 
A 1 326 ARG 326 358 358 ARG ARG B . n 
A 1 327 ASN 327 359 359 ASN ASN B . n 
A 1 328 ILE 328 360 360 ILE ILE B . n 
A 1 329 TRP 329 361 361 TRP TRP B . n 
A 1 330 PHE 330 362 362 PHE PHE B . n 
A 1 331 ALA 331 363 363 ALA ALA B . n 
A 1 332 GLU 332 364 364 GLU GLU B . n 
A 1 333 PHE 333 365 365 PHE PHE B . n 
A 1 334 TRP 334 366 366 TRP TRP B . n 
A 1 335 GLU 335 367 367 GLU GLU B . n 
A 1 336 ASP 336 368 368 ASP ASP B . n 
A 1 337 ASN 337 369 369 ASN ASN B . n 
A 1 338 PHE 338 370 370 PHE PHE B . n 
A 1 339 HIS 339 371 371 HIS HIS B . n 
A 1 340 CYS 340 372 372 CYS CYS B . n 
A 1 341 LYS 341 373 373 LYS LYS B . n 
A 1 342 LEU 342 374 374 LEU LEU B . n 
A 1 343 SER 343 375 ?   ?   ?   B . n 
A 1 344 ARG 344 376 ?   ?   ?   B . n 
A 1 345 HIS 345 377 ?   ?   ?   B . n 
A 1 346 ALA 346 378 ?   ?   ?   B . n 
A 1 347 LEU 347 379 ?   ?   ?   B . n 
A 1 348 LYS 348 380 ?   ?   ?   B . n 
A 1 349 LYS 349 381 ?   ?   ?   B . n 
A 1 350 GLY 350 382 ?   ?   ?   B . n 
A 1 351 SER 351 383 ?   ?   ?   B . n 
A 1 352 HIS 352 384 ?   ?   ?   B . n 
A 1 353 VAL 353 385 385 VAL VAL B . n 
A 1 354 LYS 354 386 386 LYS LYS B . n 
A 1 355 LYS 355 387 387 LYS LYS B . n 
A 1 356 CYS 356 388 388 CYS CYS B . n 
A 1 357 THR 357 389 389 THR THR B . n 
A 1 358 ASN 358 390 390 ASN ASN B . n 
A 1 359 ARG 359 391 391 ARG ARG B . n 
A 1 360 GLU 360 392 392 GLU GLU B . n 
A 1 361 ARG 361 393 393 ARG ARG B . n 
A 1 362 ILE 362 394 394 ILE ILE B . n 
A 1 363 GLY 363 395 395 GLY GLY B . n 
A 1 364 GLN 364 396 396 GLN GLN B . n 
A 1 365 ASP 365 397 397 ASP ASP B . n 
A 1 366 SER 366 398 398 SER SER B . n 
A 1 367 ALA 367 399 399 ALA ALA B . n 
A 1 368 TYR 368 400 400 TYR TYR B . n 
A 1 369 GLU 369 401 401 GLU GLU B . n 
A 1 370 GLN 370 402 402 GLN GLN B . n 
A 1 371 GLU 371 403 403 GLU GLU B . n 
A 1 372 GLY 372 404 404 GLY GLY B . n 
A 1 373 LYS 373 405 405 LYS LYS B . n 
A 1 374 VAL 374 406 406 VAL VAL B . n 
A 1 375 GLN 375 407 407 GLN GLN B . n 
A 1 376 PHE 376 408 408 PHE PHE B . n 
A 1 377 VAL 377 409 409 VAL VAL B . n 
A 1 378 ILE 378 410 410 ILE ILE B . n 
A 1 379 ASP 379 411 411 ASP ASP B . n 
A 1 380 ALA 380 412 412 ALA ALA B . n 
A 1 381 VAL 381 413 413 VAL VAL B . n 
A 1 382 TYR 382 414 414 TYR TYR B . n 
A 1 383 ALA 383 415 415 ALA ALA B . n 
A 1 384 MET 384 416 416 MET MET B . n 
A 1 385 GLY 385 417 417 GLY GLY B . n 
A 1 386 HIS 386 418 418 HIS HIS B . n 
A 1 387 ALA 387 419 419 ALA ALA B . n 
A 1 388 LEU 388 420 420 LEU LEU B . n 
A 1 389 HIS 389 421 421 HIS HIS B . n 
A 1 390 ALA 390 422 422 ALA ALA B . n 
A 1 391 MET 391 423 423 MET MET B . n 
A 1 392 HIS 392 424 424 HIS HIS B . n 
A 1 393 ARG 393 425 425 ARG ARG B . n 
A 1 394 ASP 394 426 426 ASP ASP B . n 
A 1 395 LEU 395 427 427 LEU LEU B . n 
A 1 396 CYS 396 428 428 CYS CYS B . n 
A 1 397 PRO 397 429 429 PRO PRO B . n 
A 1 398 GLY 398 430 430 GLY GLY B . n 
A 1 399 ARG 399 431 431 ARG ARG B . n 
A 1 400 VAL 400 432 432 VAL VAL B . n 
A 1 401 GLY 401 433 433 GLY GLY B . n 
A 1 402 LEU 402 434 434 LEU LEU B . n 
A 1 403 CYS 403 435 435 CYS CYS B . n 
A 1 404 PRO 404 436 436 PRO PRO B . n 
A 1 405 ARG 405 437 437 ARG ARG B . n 
A 1 406 MET 406 438 438 MET MET B . n 
A 1 407 ASP 407 439 439 ASP ASP B . n 
A 1 408 PRO 408 440 440 PRO PRO B . n 
A 1 409 VAL 409 441 441 VAL VAL B . n 
A 1 410 ASP 410 442 442 ASP ASP B . n 
A 1 411 GLY 411 443 443 GLY GLY B . n 
A 1 412 THR 412 444 444 THR THR B . n 
A 1 413 GLN 413 445 445 GLN GLN B . n 
A 1 414 LEU 414 446 446 LEU LEU B . n 
A 1 415 LEU 415 447 447 LEU LEU B . n 
A 1 416 LYS 416 448 448 LYS LYS B . n 
A 1 417 TYR 417 449 449 TYR TYR B . n 
A 1 418 ILE 418 450 450 ILE ILE B . n 
A 1 419 ARG 419 451 451 ARG ARG B . n 
A 1 420 ASN 420 452 452 ASN ASN B . n 
A 1 421 VAL 421 453 453 VAL VAL B . n 
A 1 422 ASN 422 454 454 ASN ASN B . n 
A 1 423 PHE 423 455 455 PHE PHE B . n 
A 1 424 SER 424 456 456 SER SER B . n 
A 1 425 GLY 425 457 457 GLY GLY B . n 
A 1 426 ILE 426 458 458 ILE ILE B . n 
A 1 427 ALA 427 459 459 ALA ALA B . n 
A 1 428 GLY 428 460 460 GLY GLY B . n 
A 1 429 ASN 429 461 461 ASN ASN B . n 
A 1 430 PRO 430 462 462 PRO PRO B . n 
A 1 431 VAL 431 463 463 VAL VAL B . n 
A 1 432 THR 432 464 464 THR THR B . n 
A 1 433 PHE 433 465 465 PHE PHE B . n 
A 1 434 ASN 434 466 466 ASN ASN B . n 
A 1 435 GLU 435 467 467 GLU GLU B . n 
A 1 436 ASN 436 468 468 ASN ASN B . n 
A 1 437 GLY 437 469 469 GLY GLY B . n 
A 1 438 ASP 438 470 470 ASP ASP B . n 
A 1 439 ALA 439 471 471 ALA ALA B . n 
A 1 440 PRO 440 472 472 PRO PRO B . n 
A 1 441 GLY 441 473 473 GLY GLY B . n 
A 1 442 ARG 442 474 474 ARG ARG B . n 
A 1 443 TYR 443 475 475 TYR TYR B . n 
A 1 444 ASP 444 476 476 ASP ASP B . n 
A 1 445 ILE 445 477 477 ILE ILE B . n 
A 1 446 TYR 446 478 478 TYR TYR B . n 
A 1 447 GLN 447 479 479 GLN GLN B . n 
A 1 448 TYR 448 480 480 TYR TYR B . n 
A 1 449 GLN 449 481 481 GLN GLN B . n 
A 1 450 LEU 450 482 482 LEU LEU B . n 
A 1 451 ARG 451 483 483 ARG ARG B . n 
A 1 452 ASN 452 484 ?   ?   ?   B . n 
A 1 453 ASP 453 485 ?   ?   ?   B . n 
A 1 454 SER 454 486 ?   ?   ?   B . n 
A 1 455 ALA 455 487 487 ALA ALA B . n 
A 1 456 GLU 456 488 488 GLU GLU B . n 
A 1 457 TYR 457 489 489 TYR TYR B . n 
A 1 458 LYS 458 490 490 LYS LYS B . n 
A 1 459 VAL 459 491 491 VAL VAL B . n 
A 1 460 ILE 460 492 492 ILE ILE B . n 
A 1 461 GLY 461 493 493 GLY GLY B . n 
A 1 462 SER 462 494 494 SER SER B . n 
A 1 463 TRP 463 495 495 TRP TRP B . n 
A 1 464 THR 464 496 496 THR THR B . n 
A 1 465 ASP 465 497 497 ASP ASP B . n 
A 1 466 HIS 466 498 498 HIS HIS B . n 
A 1 467 LEU 467 499 499 LEU LEU B . n 
A 1 468 HIS 468 500 500 HIS HIS B . n 
A 1 469 LEU 469 501 501 LEU LEU B . n 
A 1 470 ARG 470 502 502 ARG ARG B . n 
A 1 471 ILE 471 503 503 ILE ILE B . n 
A 1 472 GLU 472 504 ?   ?   ?   B . n 
A 1 473 ARG 473 505 ?   ?   ?   B . n 
A 1 474 MET 474 506 ?   ?   ?   B . n 
A 1 475 HIS 475 507 ?   ?   ?   B . n 
A 1 476 TRP 476 508 ?   ?   ?   B . n 
A 1 477 PRO 477 509 ?   ?   ?   B . n 
A 1 478 GLY 478 510 ?   ?   ?   B . n 
A 1 479 SER 479 511 ?   ?   ?   B . n 
A 1 480 GLY 480 512 ?   ?   ?   B . n 
A 1 481 GLN 481 513 513 GLN GLN B . n 
A 1 482 GLN 482 514 514 GLN GLN B . n 
A 1 483 LEU 483 515 515 LEU LEU B . n 
A 1 484 PRO 484 516 516 PRO PRO B . n 
A 1 485 ARG 485 517 517 ARG ARG B . n 
A 1 486 SER 486 518 518 SER SER B . n 
A 1 487 ILE 487 519 519 ILE ILE B . n 
A 1 488 CYS 488 520 520 CYS CYS B . n 
A 1 489 SER 489 521 521 SER SER B . n 
A 1 490 LEU 490 522 522 LEU LEU B . n 
A 1 491 PRO 491 523 523 PRO PRO B . n 
A 1 492 CYS 492 524 524 CYS CYS B . n 
A 1 493 GLN 493 525 525 GLN GLN B . n 
A 1 494 PRO 494 526 526 PRO PRO B . n 
A 1 495 GLY 495 527 527 GLY GLY B . n 
A 1 496 GLU 496 528 528 GLU GLU B . n 
A 1 497 ARG 497 529 529 ARG ARG B . n 
A 1 498 LYS 498 530 530 LYS LYS B . n 
A 1 499 LYS 499 531 531 LYS LYS B . n 
A 1 500 THR 500 532 532 THR THR B . n 
A 1 501 VAL 501 533 533 VAL VAL B . n 
A 1 502 LYS 502 534 534 LYS LYS B . n 
A 1 503 GLY 503 535 535 GLY GLY B . n 
A 1 504 MET 504 536 536 MET MET B . n 
A 1 505 PRO 505 537 537 PRO PRO B . n 
A 1 506 CYS 506 538 538 CYS CYS B . n 
A 1 507 CYS 507 539 539 CYS CYS B . n 
A 1 508 TRP 508 540 540 TRP TRP B . n 
A 1 509 HIS 509 541 541 HIS HIS B . n 
A 1 510 CYS 510 542 542 CYS CYS B . n 
A 1 511 GLU 511 543 543 GLU GLU B . n 
A 1 512 PRO 512 544 544 PRO PRO B . n 
A 1 513 CYS 513 545 545 CYS CYS B . n 
A 1 514 THR 514 546 546 THR THR B . n 
A 1 515 GLY 515 547 547 GLY GLY B . n 
A 1 516 TYR 516 548 548 TYR TYR B . n 
A 1 517 GLN 517 549 549 GLN GLN B . n 
A 1 518 TYR 518 550 550 TYR TYR B . n 
A 1 519 GLN 519 551 551 GLN GLN B . n 
A 1 520 VAL 520 552 552 VAL VAL B . n 
A 1 521 ASP 521 553 553 ASP ASP B . n 
A 1 522 ARG 522 554 554 ARG ARG B . n 
A 1 523 TYR 523 555 555 TYR TYR B . n 
A 1 524 THR 524 556 556 THR THR B . n 
A 1 525 CYS 525 557 557 CYS CYS B . n 
A 1 526 LYS 526 558 558 LYS LYS B . n 
A 1 527 THR 527 559 559 THR THR B . n 
A 1 528 CYS 528 560 560 CYS CYS B . n 
A 1 529 PRO 529 561 561 PRO PRO B . n 
A 1 530 TYR 530 562 562 TYR TYR B . n 
A 1 531 ASP 531 563 563 ASP ASP B . n 
A 1 532 MET 532 564 564 MET MET B . n 
A 1 533 ARG 533 565 565 ARG ARG B . n 
A 1 534 PRO 534 566 566 PRO PRO B . n 
A 1 535 THR 535 567 567 THR THR B . n 
A 1 536 GLU 536 568 568 GLU GLU B . n 
A 1 537 ASN 537 569 569 ASN ASN B . n 
A 1 538 ARG 538 570 570 ARG ARG B . n 
A 1 539 THR 539 571 571 THR THR B . n 
A 1 540 GLY 540 572 572 GLY GLY B . n 
A 1 541 CYS 541 573 573 CYS CYS B . n 
A 1 542 ARG 542 574 574 ARG ARG B . n 
A 1 543 PRO 543 575 575 PRO PRO B . n 
A 1 544 ILE 544 576 576 ILE ILE B . n 
A 1 545 PRO 545 577 577 PRO PRO B . n 
A 1 546 ILE 546 578 578 ILE ILE B . n 
A 1 547 ILE 547 579 579 ILE ILE B . n 
A 1 548 LYS 548 580 580 LYS LYS B . n 
A 1 549 LEU 549 581 581 LEU LEU B . n 
A 1 550 GLU 550 582 582 GLU GLU B . n 
A 1 551 TRP 551 583 583 TRP TRP B . n 
A 1 552 GLY 552 584 584 GLY GLY B . n 
A 1 553 SER 553 585 585 SER SER B . n 
A 1 554 PRO 554 586 586 PRO PRO B . n 
A 1 555 TRP 555 587 587 TRP TRP B . n 
A 1 556 ALA 556 588 588 ALA ALA B . n 
A 1 557 VAL 557 589 589 VAL VAL B . n 
A 1 558 LEU 558 590 590 LEU LEU B . n 
A 1 559 PRO 559 591 591 PRO PRO B . n 
A 1 560 LEU 560 592 592 LEU LEU B . n 
A 1 561 PHE 561 593 593 PHE PHE B . n 
A 1 562 LEU 562 594 594 LEU LEU B . n 
A 1 563 ALA 563 595 595 ALA ALA B . n 
A 1 564 VAL 564 596 596 VAL VAL B . n 
A 1 565 VAL 565 597 597 VAL VAL B . n 
A 1 566 GLY 566 598 598 GLY GLY B . n 
A 1 567 ILE 567 599 599 ILE ILE B . n 
A 1 568 ALA 568 600 600 ALA ALA B . n 
A 1 569 ALA 569 601 601 ALA ALA B . n 
A 1 570 THR 570 602 602 THR THR B . n 
A 1 571 LEU 571 603 603 LEU LEU B . n 
A 1 572 PHE 572 604 604 PHE PHE B . n 
A 1 573 VAL 573 605 605 VAL VAL B . n 
A 1 574 VAL 574 606 606 VAL VAL B . n 
A 1 575 ILE 575 607 607 ILE ILE B . n 
A 1 576 THR 576 608 608 THR THR B . n 
A 1 577 PHE 577 609 609 PHE PHE B . n 
A 1 578 VAL 578 610 610 VAL VAL B . n 
A 1 579 ARG 579 611 611 ARG ARG B . n 
A 1 580 TYR 580 612 612 TYR TYR B . n 
A 1 581 ASN 581 613 613 ASN ASN B . n 
A 1 582 ASP 582 614 614 ASP ASP B . n 
A 1 583 THR 583 615 615 THR THR B . n 
A 1 584 PRO 584 616 616 PRO PRO B . n 
A 1 585 ILE 585 617 617 ILE ILE B . n 
A 1 586 VAL 586 618 618 VAL VAL B . n 
A 1 587 LYS 587 619 619 LYS LYS B . n 
A 1 588 ALA 588 620 620 ALA ALA B . n 
A 1 589 SER 589 621 621 SER SER B . n 
A 1 590 GLY 590 622 622 GLY GLY B . n 
A 1 591 ARG 591 623 623 ARG ARG B . n 
A 1 592 GLU 592 624 624 GLU GLU B . n 
A 1 593 LEU 593 625 625 LEU LEU B . n 
A 1 594 SER 594 626 626 SER SER B . n 
A 1 595 TYR 595 627 627 TYR TYR B . n 
A 1 596 VAL 596 628 628 VAL VAL B . n 
A 1 597 LEU 597 629 629 LEU LEU B . n 
A 1 598 LEU 598 630 630 LEU LEU B . n 
A 1 599 ALA 599 631 631 ALA ALA B . n 
A 1 600 GLY 600 632 632 GLY GLY B . n 
A 1 601 ILE 601 633 633 ILE ILE B . n 
A 1 602 PHE 602 634 634 PHE PHE B . n 
A 1 603 LEU 603 635 635 LEU LEU B . n 
A 1 604 CYS 604 636 636 CYS CYS B . n 
A 1 605 TYR 605 637 637 TYR TYR B . n 
A 1 606 ALA 606 638 638 ALA ALA B . n 
A 1 607 THR 607 639 639 THR THR B . n 
A 1 608 THR 608 640 640 THR THR B . n 
A 1 609 PHE 609 641 641 PHE PHE B . n 
A 1 610 LEU 610 642 642 LEU LEU B . n 
A 1 611 MET 611 643 643 MET MET B . n 
A 1 612 ILE 612 644 644 ILE ILE B . n 
A 1 613 ALA 613 645 645 ALA ALA B . n 
A 1 614 GLU 614 646 646 GLU GLU B . n 
A 1 615 PRO 615 647 647 PRO PRO B . n 
A 1 616 ASP 616 648 648 ASP ASP B . n 
A 1 617 LEU 617 649 649 LEU LEU B . n 
A 1 618 GLY 618 650 650 GLY GLY B . n 
A 1 619 THR 619 651 651 THR THR B . n 
A 1 620 CYS 620 652 652 CYS CYS B . n 
A 1 621 SER 621 653 653 SER SER B . n 
A 1 622 LEU 622 654 654 LEU LEU B . n 
A 1 623 ARG 623 655 655 ARG ARG B . n 
A 1 624 ARG 624 656 656 ARG ARG B . n 
A 1 625 ILE 625 657 657 ILE ILE B . n 
A 1 626 PHE 626 658 658 PHE PHE B . n 
A 1 627 LEU 627 659 659 LEU LEU B . n 
A 1 628 GLY 628 660 660 GLY GLY B . n 
A 1 629 LEU 629 661 661 LEU LEU B . n 
A 1 630 GLY 630 662 662 GLY GLY B . n 
A 1 631 MET 631 663 663 MET MET B . n 
A 1 632 SER 632 664 664 SER SER B . n 
A 1 633 ILE 633 665 665 ILE ILE B . n 
A 1 634 SER 634 666 666 SER SER B . n 
A 1 635 TYR 635 667 667 TYR TYR B . n 
A 1 636 ALA 636 668 668 ALA ALA B . n 
A 1 637 ALA 637 669 669 ALA ALA B . n 
A 1 638 LEU 638 670 670 LEU LEU B . n 
A 1 639 LEU 639 671 671 LEU LEU B . n 
A 1 640 THR 640 672 672 THR THR B . n 
A 1 641 LYS 641 673 673 LYS LYS B . n 
A 1 642 THR 642 674 674 THR THR B . n 
A 1 643 ASN 643 675 675 ASN ASN B . n 
A 1 644 ARG 644 676 676 ARG ARG B . n 
A 1 645 ILE 645 677 677 ILE ILE B . n 
A 1 646 TYR 646 678 678 TYR TYR B . n 
A 1 647 ARG 647 679 679 ARG ARG B . n 
A 1 648 ILE 648 680 680 ILE ILE B . n 
A 1 649 PHE 649 681 681 PHE PHE B . n 
A 1 650 GLU 650 682 682 GLU GLU B . n 
A 1 651 GLN 651 683 683 GLN GLN B . n 
A 1 652 GLY 652 684 684 GLY GLY B . n 
A 1 653 LYS 653 685 685 LYS LYS B . n 
A 1 654 ARG 654 686 686 ARG ARG B . n 
A 1 655 SER 655 687 687 SER SER B . n 
A 1 656 VAL 656 688 688 VAL VAL B . n 
A 1 657 SER 657 689 689 SER SER B . n 
A 1 658 ALA 658 690 690 ALA ALA B . n 
A 1 659 PRO 659 691 691 PRO PRO B . n 
A 1 660 ARG 660 692 692 ARG ARG B . n 
A 1 661 PHE 661 693 693 PHE PHE B . n 
A 1 662 ILE 662 694 694 ILE ILE B . n 
A 1 663 SER 663 695 695 SER SER B . n 
A 1 664 PRO 664 696 696 PRO PRO B . n 
A 1 665 ALA 665 697 697 ALA ALA B . n 
A 1 666 SER 666 698 698 SER SER B . n 
A 1 667 GLN 667 699 699 GLN GLN B . n 
A 1 668 LEU 668 700 700 LEU LEU B . n 
A 1 669 ALA 669 701 701 ALA ALA B . n 
A 1 670 ILE 670 702 702 ILE ILE B . n 
A 1 671 THR 671 703 703 THR THR B . n 
A 1 672 PHE 672 704 704 PHE PHE B . n 
A 1 673 SER 673 705 705 SER SER B . n 
A 1 674 LEU 674 706 706 LEU LEU B . n 
A 1 675 ILE 675 707 707 ILE ILE B . n 
A 1 676 SER 676 708 708 SER SER B . n 
A 1 677 LEU 677 709 709 LEU LEU B . n 
A 1 678 GLN 678 710 710 GLN GLN B . n 
A 1 679 LEU 679 711 711 LEU LEU B . n 
A 1 680 LEU 680 712 712 LEU LEU B . n 
A 1 681 GLY 681 713 713 GLY GLY B . n 
A 1 682 ILE 682 714 714 ILE ILE B . n 
A 1 683 CYS 683 715 715 CYS CYS B . n 
A 1 684 VAL 684 716 716 VAL VAL B . n 
A 1 685 TRP 685 717 717 TRP TRP B . n 
A 1 686 PHE 686 718 718 PHE PHE B . n 
A 1 687 VAL 687 719 719 VAL VAL B . n 
A 1 688 VAL 688 720 720 VAL VAL B . n 
A 1 689 ASP 689 721 721 ASP ASP B . n 
A 1 690 PRO 690 722 722 PRO PRO B . n 
A 1 691 SER 691 723 723 SER SER B . n 
A 1 692 HIS 692 724 724 HIS HIS B . n 
A 1 693 SER 693 725 725 SER SER B . n 
A 1 694 VAL 694 726 726 VAL VAL B . n 
A 1 695 VAL 695 727 727 VAL VAL B . n 
A 1 696 ASP 696 728 728 ASP ASP B . n 
A 1 697 PHE 697 729 729 PHE PHE B . n 
A 1 698 GLN 698 730 730 GLN GLN B . n 
A 1 699 ASP 699 731 731 ASP ASP B . n 
A 1 700 GLN 700 732 732 GLN GLN B . n 
A 1 701 ARG 701 733 733 ARG ARG B . n 
A 1 702 THR 702 734 734 THR THR B . n 
A 1 703 LEU 703 735 735 LEU LEU B . n 
A 1 704 ASP 704 736 736 ASP ASP B . n 
A 1 705 PRO 705 737 737 PRO PRO B . n 
A 1 706 ARG 706 738 738 ARG ARG B . n 
A 1 707 PHE 707 739 739 PHE PHE B . n 
A 1 708 ALA 708 740 740 ALA ALA B . n 
A 1 709 ARG 709 741 741 ARG ARG B . n 
A 1 710 GLY 710 742 742 GLY GLY B . n 
A 1 711 VAL 711 743 743 VAL VAL B . n 
A 1 712 LEU 712 744 744 LEU LEU B . n 
A 1 713 LYS 713 745 745 LYS LYS B . n 
A 1 714 CYS 714 746 746 CYS CYS B . n 
A 1 715 ASP 715 747 747 ASP ASP B . n 
A 1 716 ILE 716 748 748 ILE ILE B . n 
A 1 717 SER 717 749 749 SER SER B . n 
A 1 718 ASP 718 750 750 ASP ASP B . n 
A 1 719 LEU 719 751 751 LEU LEU B . n 
A 1 720 SER 720 752 752 SER SER B . n 
A 1 721 LEU 721 753 753 LEU LEU B . n 
A 1 722 ILE 722 754 754 ILE ILE B . n 
A 1 723 CYS 723 755 755 CYS CYS B . n 
A 1 724 LEU 724 756 756 LEU LEU B . n 
A 1 725 LEU 725 757 757 LEU LEU B . n 
A 1 726 GLY 726 758 758 GLY GLY B . n 
A 1 727 TYR 727 759 759 TYR TYR B . n 
A 1 728 SER 728 760 760 SER SER B . n 
A 1 729 MET 729 761 761 MET MET B . n 
A 1 730 LEU 730 762 762 LEU LEU B . n 
A 1 731 LEU 731 763 763 LEU LEU B . n 
A 1 732 MET 732 764 764 MET MET B . n 
A 1 733 VAL 733 765 765 VAL VAL B . n 
A 1 734 THR 734 766 766 THR THR B . n 
A 1 735 CYS 735 767 767 CYS CYS B . n 
A 1 736 THR 736 768 768 THR THR B . n 
A 1 737 VAL 737 769 769 VAL VAL B . n 
A 1 738 TYR 738 770 770 TYR TYR B . n 
A 1 739 ALA 739 771 771 ALA ALA B . n 
A 1 740 ILE 740 772 772 ILE ILE B . n 
A 1 741 LYS 741 773 773 LYS LYS B . n 
A 1 742 THR 742 774 774 THR THR B . n 
A 1 743 ARG 743 775 775 ARG ARG B . n 
A 1 744 GLY 744 776 776 GLY GLY B . n 
A 1 745 VAL 745 777 777 VAL VAL B . n 
A 1 746 PRO 746 778 778 PRO PRO B . n 
A 1 747 GLU 747 779 779 GLU GLU B . n 
A 1 748 THR 748 780 780 THR THR B . n 
A 1 749 PHE 749 781 781 PHE PHE B . n 
A 1 750 ASN 750 782 782 ASN ASN B . n 
A 1 751 GLU 751 783 783 GLU GLU B . n 
A 1 752 ALA 752 784 784 ALA ALA B . n 
A 1 753 LYS 753 785 785 LYS LYS B . n 
A 1 754 PRO 754 786 786 PRO PRO B . n 
A 1 755 ILE 755 787 787 ILE ILE B . n 
A 1 756 GLY 756 788 788 GLY GLY B . n 
A 1 757 PHE 757 789 789 PHE PHE B . n 
A 1 758 THR 758 790 790 THR THR B . n 
A 1 759 MET 759 791 791 MET MET B . n 
A 1 760 TYR 760 792 792 TYR TYR B . n 
A 1 761 THR 761 793 793 THR THR B . n 
A 1 762 THR 762 794 794 THR THR B . n 
A 1 763 CYS 763 795 795 CYS CYS B . n 
A 1 764 ILE 764 796 796 ILE ILE B . n 
A 1 765 VAL 765 797 797 VAL VAL B . n 
A 1 766 TRP 766 798 798 TRP TRP B . n 
A 1 767 LEU 767 799 799 LEU LEU B . n 
A 1 768 ALA 768 800 800 ALA ALA B . n 
A 1 769 PHE 769 801 801 PHE PHE B . n 
A 1 770 ILE 770 802 802 ILE ILE B . n 
A 1 771 PRO 771 803 803 PRO PRO B . n 
A 1 772 ILE 772 804 804 ILE ILE B . n 
A 1 773 PHE 773 805 805 PHE PHE B . n 
A 1 774 PHE 774 806 806 PHE PHE B . n 
A 1 775 GLY 775 807 807 GLY GLY B . n 
A 1 776 THR 776 808 808 THR THR B . n 
A 1 777 SER 777 809 809 SER SER B . n 
A 1 778 GLN 778 810 810 GLN GLN B . n 
A 1 779 SER 779 811 811 SER SER B . n 
A 1 780 ALA 780 812 812 ALA ALA B . n 
A 1 781 ASP 781 813 813 ASP ASP B . n 
A 1 782 LYS 782 814 814 LYS LYS B . n 
A 1 783 LEU 783 815 815 LEU LEU B . n 
A 1 784 TYR 784 816 816 TYR TYR B . n 
A 1 785 ILE 785 817 817 ILE ILE B . n 
A 1 786 GLN 786 818 818 GLN GLN B . n 
A 1 787 THR 787 819 819 THR THR B . n 
A 1 788 THR 788 820 820 THR THR B . n 
A 1 789 THR 789 821 821 THR THR B . n 
A 1 790 LEU 790 822 822 LEU LEU B . n 
A 1 791 THR 791 823 823 THR THR B . n 
A 1 792 VAL 792 824 824 VAL VAL B . n 
A 1 793 SER 793 825 825 SER SER B . n 
A 1 794 VAL 794 826 826 VAL VAL B . n 
A 1 795 SER 795 827 827 SER SER B . n 
A 1 796 LEU 796 828 828 LEU LEU B . n 
A 1 797 SER 797 829 829 SER SER B . n 
A 1 798 ALA 798 830 830 ALA ALA B . n 
A 1 799 SER 799 831 831 SER SER B . n 
A 1 800 VAL 800 832 832 VAL VAL B . n 
A 1 801 SER 801 833 833 SER SER B . n 
A 1 802 LEU 802 834 834 LEU LEU B . n 
A 1 803 GLY 803 835 835 GLY GLY B . n 
A 1 804 MET 804 836 836 MET MET B . n 
A 1 805 LEU 805 837 837 LEU LEU B . n 
A 1 806 TYR 806 838 838 TYR TYR B . n 
A 1 807 MET 807 839 839 MET MET B . n 
A 1 808 PRO 808 840 840 PRO PRO B . n 
A 1 809 LYS 809 841 841 LYS LYS B . n 
A 1 810 VAL 810 842 842 VAL VAL B . n 
A 1 811 TYR 811 843 843 TYR TYR B . n 
A 1 812 ILE 812 844 844 ILE ILE B . n 
A 1 813 ILE 813 845 845 ILE ILE B . n 
A 1 814 LEU 814 846 846 LEU LEU B . n 
A 1 815 PHE 815 847 847 PHE PHE B . n 
A 1 816 HIS 816 848 848 HIS HIS B . n 
A 1 817 PRO 817 849 849 PRO PRO B . n 
A 1 818 GLU 818 850 850 GLU GLU B . n 
A 1 819 GLN 819 851 851 GLN GLN B . n 
A 1 820 ASN 820 852 852 ASN ASN B . n 
A 1 821 VAL 821 853 853 VAL VAL B . n 
A 1 822 PRO 822 854 854 PRO PRO B . n 
A 1 823 LYS 823 855 855 LYS LYS B . n 
A 1 824 ARG 824 856 ?   ?   ?   B . n 
A 1 825 LYS 825 857 ?   ?   ?   B . n 
A 1 826 ARG 826 858 ?   ?   ?   B . n 
A 1 827 SER 827 859 ?   ?   ?   B . n 
A 1 828 LEU 828 860 ?   ?   ?   B . n 
A 1 829 LYS 829 861 ?   ?   ?   B . n 
A 1 830 ALA 830 862 ?   ?   ?   B . n 
A 1 831 VAL 831 863 ?   ?   ?   B . n 
A 1 832 VAL 832 864 ?   ?   ?   B . n 
A 1 833 THR 833 865 ?   ?   ?   B . n 
A 1 834 ALA 834 866 ?   ?   ?   B . n 
A 1 835 ALA 835 867 ?   ?   ?   B . n 
A 1 836 THR 836 868 ?   ?   ?   B . n 
A 1 837 MET 837 869 ?   ?   ?   B . n 
A 1 838 SER 838 870 ?   ?   ?   B . n 
A 1 839 ASN 839 871 ?   ?   ?   B . n 
A 1 840 LYS 840 872 ?   ?   ?   B . n 
A 1 841 PHE 841 873 ?   ?   ?   B . n 
A 1 842 THR 842 874 ?   ?   ?   B . n 
A 1 843 GLN 843 875 ?   ?   ?   B . n 
A 1 844 LYS 844 876 ?   ?   ?   B . n 
A 1 845 GLY 845 877 ?   ?   ?   B . n 
A 1 846 ASN 846 878 ?   ?   ?   B . n 
A 1 847 PHE 847 879 ?   ?   ?   B . n 
A 1 848 ARG 848 880 ?   ?   ?   B . n 
A 1 849 PRO 849 881 ?   ?   ?   B . n 
A 1 850 ASN 850 882 ?   ?   ?   B . n 
A 1 851 GLY 851 883 ?   ?   ?   B . n 
A 1 852 GLU 852 884 ?   ?   ?   B . n 
A 1 853 ALA 853 885 ?   ?   ?   B . n 
A 1 854 LYS 854 886 ?   ?   ?   B . n 
A 1 855 SER 855 887 ?   ?   ?   B . n 
A 1 856 GLU 856 888 ?   ?   ?   B . n 
A 1 857 LEU 857 889 ?   ?   ?   B . n 
A 1 858 CYS 858 890 ?   ?   ?   B . n 
A 1 859 GLU 859 891 ?   ?   ?   B . n 
A 1 860 ASN 860 892 ?   ?   ?   B . n 
A 1 861 LEU 861 893 ?   ?   ?   B . n 
A 1 862 GLU 862 894 ?   ?   ?   B . n 
A 1 863 ALA 863 895 ?   ?   ?   B . n 
A 1 864 PRO 864 896 ?   ?   ?   B . n 
A 1 865 ALA 865 897 ?   ?   ?   B . n 
A 1 866 LEU 866 898 ?   ?   ?   B . n 
A 1 867 ALA 867 899 ?   ?   ?   B . n 
A 1 868 THR 868 900 ?   ?   ?   B . n 
A 1 869 LYS 869 901 ?   ?   ?   B . n 
A 1 870 GLN 870 902 ?   ?   ?   B . n 
A 1 871 THR 871 903 ?   ?   ?   B . n 
A 1 872 TYR 872 904 ?   ?   ?   B . n 
A 1 873 VAL 873 905 ?   ?   ?   B . n 
A 1 874 THR 874 906 ?   ?   ?   B . n 
A 1 875 TYR 875 907 ?   ?   ?   B . n 
A 1 876 THR 876 908 ?   ?   ?   B . n 
A 1 877 ASN 877 909 ?   ?   ?   B . n 
A 1 878 HIS 878 910 ?   ?   ?   B . n 
A 1 879 ALA 879 911 ?   ?   ?   B . n 
A 1 880 ILE 880 912 ?   ?   ?   B . n 
B 2 1   GLU 1   19  ?   ?   ?   C . n 
B 2 2   GLY 2   20  ?   ?   ?   C . n 
B 2 3   PRO 3   21  ?   ?   ?   C . n 
B 2 4   ALA 4   22  ?   ?   ?   C . n 
B 2 5   LYS 5   23  23  LYS LYS C . n 
B 2 6   LYS 6   24  24  LYS LYS C . n 
B 2 7   VAL 7   25  25  VAL VAL C . n 
B 2 8   LEU 8   26  26  LEU LEU C . n 
B 2 9   THR 9   27  27  THR THR C . n 
B 2 10  LEU 10  28  28  LEU LEU C . n 
B 2 11  GLU 11  29  29  GLU GLU C . n 
B 2 12  GLY 12  30  30  GLY GLY C . n 
B 2 13  ASP 13  31  31  ASP ASP C . n 
B 2 14  LEU 14  32  32  LEU LEU C . n 
B 2 15  VAL 15  33  33  VAL VAL C . n 
B 2 16  LEU 16  34  34  LEU LEU C . n 
B 2 17  GLY 17  35  35  GLY GLY C . n 
B 2 18  GLY 18  36  36  GLY GLY C . n 
B 2 19  LEU 19  37  37  LEU LEU C . n 
B 2 20  PHE 20  38  38  PHE PHE C . n 
B 2 21  PRO 21  39  39  PRO PRO C . n 
B 2 22  VAL 22  40  40  VAL VAL C . n 
B 2 23  HIS 23  41  41  HIS HIS C . n 
B 2 24  GLN 24  42  42  GLN GLN C . n 
B 2 25  LYS 25  43  43  LYS LYS C . n 
B 2 26  GLY 26  44  44  GLY GLY C . n 
B 2 27  GLY 27  45  45  GLY GLY C . n 
B 2 28  PRO 28  46  46  PRO PRO C . n 
B 2 29  ALA 29  47  47  ALA ALA C . n 
B 2 30  GLU 30  48  48  GLU GLU C . n 
B 2 31  ASP 31  49  49  ASP ASP C . n 
B 2 32  CYS 32  50  50  CYS CYS C . n 
B 2 33  GLY 33  51  51  GLY GLY C . n 
B 2 34  PRO 34  52  52  PRO PRO C . n 
B 2 35  VAL 35  53  53  VAL VAL C . n 
B 2 36  ASN 36  54  54  ASN ASN C . n 
B 2 37  GLU 37  55  55  GLU GLU C . n 
B 2 38  HIS 38  56  56  HIS HIS C . n 
B 2 39  ARG 39  57  57  ARG ARG C . n 
B 2 40  GLY 40  58  58  GLY GLY C . n 
B 2 41  ILE 41  59  59  ILE ILE C . n 
B 2 42  GLN 42  60  60  GLN GLN C . n 
B 2 43  ARG 43  61  61  ARG ARG C . n 
B 2 44  LEU 44  62  62  LEU LEU C . n 
B 2 45  GLU 45  63  63  GLU GLU C . n 
B 2 46  ALA 46  64  64  ALA ALA C . n 
B 2 47  MET 47  65  65  MET MET C . n 
B 2 48  LEU 48  66  66  LEU LEU C . n 
B 2 49  PHE 49  67  67  PHE PHE C . n 
B 2 50  ALA 50  68  68  ALA ALA C . n 
B 2 51  LEU 51  69  69  LEU LEU C . n 
B 2 52  ASP 52  70  70  ASP ASP C . n 
B 2 53  ARG 53  71  71  ARG ARG C . n 
B 2 54  ILE 54  72  72  ILE ILE C . n 
B 2 55  ASN 55  73  73  ASN ASN C . n 
B 2 56  ARG 56  74  74  ARG ARG C . n 
B 2 57  ASP 57  75  75  ASP ASP C . n 
B 2 58  PRO 58  76  76  PRO PRO C . n 
B 2 59  HIS 59  77  77  HIS HIS C . n 
B 2 60  LEU 60  78  78  LEU LEU C . n 
B 2 61  LEU 61  79  79  LEU LEU C . n 
B 2 62  PRO 62  80  80  PRO PRO C . n 
B 2 63  GLY 63  81  81  GLY GLY C . n 
B 2 64  VAL 64  82  82  VAL VAL C . n 
B 2 65  ARG 65  83  83  ARG ARG C . n 
B 2 66  LEU 66  84  84  LEU LEU C . n 
B 2 67  GLY 67  85  85  GLY GLY C . n 
B 2 68  ALA 68  86  86  ALA ALA C . n 
B 2 69  HIS 69  87  87  HIS HIS C . n 
B 2 70  ILE 70  88  88  ILE ILE C . n 
B 2 71  LEU 71  89  89  LEU LEU C . n 
B 2 72  ASP 72  90  90  ASP ASP C . n 
B 2 73  SER 73  91  91  SER SER C . n 
B 2 74  CYS 74  92  92  CYS CYS C . n 
B 2 75  SER 75  93  93  SER SER C . n 
B 2 76  LYS 76  94  94  LYS LYS C . n 
B 2 77  ASP 77  95  95  ASP ASP C . n 
B 2 78  THR 78  96  96  THR THR C . n 
B 2 79  HIS 79  97  97  HIS HIS C . n 
B 2 80  ALA 80  98  98  ALA ALA C . n 
B 2 81  LEU 81  99  99  LEU LEU C . n 
B 2 82  GLU 82  100 100 GLU GLU C . n 
B 2 83  GLN 83  101 101 GLN GLN C . n 
B 2 84  ALA 84  102 102 ALA ALA C . n 
B 2 85  LEU 85  103 103 LEU LEU C . n 
B 2 86  ASP 86  104 104 ASP ASP C . n 
B 2 87  PHE 87  105 105 PHE PHE C . n 
B 2 88  VAL 88  106 106 VAL VAL C . n 
B 2 89  ARG 89  107 107 ARG ARG C . n 
B 2 90  ALA 90  108 108 ALA ALA C . n 
B 2 91  SER 91  109 109 SER SER C . n 
B 2 92  LEU 92  110 ?   ?   ?   C . n 
B 2 93  SER 93  111 ?   ?   ?   C . n 
B 2 94  ARG 94  112 ?   ?   ?   C . n 
B 2 95  GLY 95  113 ?   ?   ?   C . n 
B 2 96  ALA 96  114 ?   ?   ?   C . n 
B 2 97  ASP 97  115 ?   ?   ?   C . n 
B 2 98  GLY 98  116 ?   ?   ?   C . n 
B 2 99  SER 99  117 ?   ?   ?   C . n 
B 2 100 ARG 100 118 ?   ?   ?   C . n 
B 2 101 HIS 101 119 ?   ?   ?   C . n 
B 2 102 ILE 102 120 ?   ?   ?   C . n 
B 2 103 CYS 103 121 ?   ?   ?   C . n 
B 2 104 PRO 104 122 ?   ?   ?   C . n 
B 2 105 ASP 105 123 ?   ?   ?   C . n 
B 2 106 GLY 106 124 ?   ?   ?   C . n 
B 2 107 SER 107 125 ?   ?   ?   C . n 
B 2 108 TYR 108 126 ?   ?   ?   C . n 
B 2 109 ALA 109 127 ?   ?   ?   C . n 
B 2 110 THR 110 128 ?   ?   ?   C . n 
B 2 111 HIS 111 129 ?   ?   ?   C . n 
B 2 112 GLY 112 130 ?   ?   ?   C . n 
B 2 113 ASP 113 131 ?   ?   ?   C . n 
B 2 114 ALA 114 132 ?   ?   ?   C . n 
B 2 115 PRO 115 133 ?   ?   ?   C . n 
B 2 116 THR 116 134 ?   ?   ?   C . n 
B 2 117 ALA 117 135 ?   ?   ?   C . n 
B 2 118 ILE 118 136 ?   ?   ?   C . n 
B 2 119 THR 119 137 ?   ?   ?   C . n 
B 2 120 GLY 120 138 ?   ?   ?   C . n 
B 2 121 VAL 121 139 139 VAL VAL C . n 
B 2 122 ILE 122 140 140 ILE ILE C . n 
B 2 123 GLY 123 141 141 GLY GLY C . n 
B 2 124 GLY 124 142 142 GLY GLY C . n 
B 2 125 SER 125 143 143 SER SER C . n 
B 2 126 TYR 126 144 144 TYR TYR C . n 
B 2 127 SER 127 145 145 SER SER C . n 
B 2 128 ASP 128 146 146 ASP ASP C . n 
B 2 129 VAL 129 147 147 VAL VAL C . n 
B 2 130 SER 130 148 148 SER SER C . n 
B 2 131 ILE 131 149 149 ILE ILE C . n 
B 2 132 GLN 132 150 150 GLN GLN C . n 
B 2 133 VAL 133 151 151 VAL VAL C . n 
B 2 134 ALA 134 152 152 ALA ALA C . n 
B 2 135 ASN 135 153 153 ASN ASN C . n 
B 2 136 LEU 136 154 154 LEU LEU C . n 
B 2 137 LEU 137 155 155 LEU LEU C . n 
B 2 138 ARG 138 156 156 ARG ARG C . n 
B 2 139 LEU 139 157 157 LEU LEU C . n 
B 2 140 PHE 140 158 158 PHE PHE C . n 
B 2 141 GLN 141 159 159 GLN GLN C . n 
B 2 142 ILE 142 160 160 ILE ILE C . n 
B 2 143 PRO 143 161 161 PRO PRO C . n 
B 2 144 GLN 144 162 162 GLN GLN C . n 
B 2 145 ILE 145 163 163 ILE ILE C . n 
B 2 146 SER 146 164 164 SER SER C . n 
B 2 147 TYR 147 165 165 TYR TYR C . n 
B 2 148 ALA 148 166 166 ALA ALA C . n 
B 2 149 SER 149 167 167 SER SER C . n 
B 2 150 THR 150 168 168 THR THR C . n 
B 2 151 SER 151 169 169 SER SER C . n 
B 2 152 ALA 152 170 170 ALA ALA C . n 
B 2 153 LYS 153 171 171 LYS LYS C . n 
B 2 154 LEU 154 172 172 LEU LEU C . n 
B 2 155 SER 155 173 173 SER SER C . n 
B 2 156 ASP 156 174 174 ASP ASP C . n 
B 2 157 LYS 157 175 175 LYS LYS C . n 
B 2 158 SER 158 176 176 SER SER C . n 
B 2 159 ARG 159 177 177 ARG ARG C . n 
B 2 160 TYR 160 178 178 TYR TYR C . n 
B 2 161 ASP 161 179 179 ASP ASP C . n 
B 2 162 TYR 162 180 180 TYR TYR C . n 
B 2 163 PHE 163 181 181 PHE PHE C . n 
B 2 164 ALA 164 182 182 ALA ALA C . n 
B 2 165 ARG 165 183 183 ARG ARG C . n 
B 2 166 THR 166 184 184 THR THR C . n 
B 2 167 VAL 167 185 185 VAL VAL C . n 
B 2 168 PRO 168 186 186 PRO PRO C . n 
B 2 169 PRO 169 187 187 PRO PRO C . n 
B 2 170 ASP 170 188 188 ASP ASP C . n 
B 2 171 PHE 171 189 189 PHE PHE C . n 
B 2 172 PHE 172 190 190 PHE PHE C . n 
B 2 173 GLN 173 191 191 GLN GLN C . n 
B 2 174 ALA 174 192 192 ALA ALA C . n 
B 2 175 LYS 175 193 193 LYS LYS C . n 
B 2 176 ALA 176 194 194 ALA ALA C . n 
B 2 177 MET 177 195 195 MET MET C . n 
B 2 178 ALA 178 196 196 ALA ALA C . n 
B 2 179 GLU 179 197 197 GLU GLU C . n 
B 2 180 ILE 180 198 198 ILE ILE C . n 
B 2 181 LEU 181 199 199 LEU LEU C . n 
B 2 182 ARG 182 200 200 ARG ARG C . n 
B 2 183 PHE 183 201 201 PHE PHE C . n 
B 2 184 PHE 184 202 202 PHE PHE C . n 
B 2 185 ASN 185 203 203 ASN ASN C . n 
B 2 186 TRP 186 204 204 TRP TRP C . n 
B 2 187 THR 187 205 205 THR THR C . n 
B 2 188 TYR 188 206 206 TYR TYR C . n 
B 2 189 VAL 189 207 207 VAL VAL C . n 
B 2 190 SER 190 208 208 SER SER C . n 
B 2 191 THR 191 209 209 THR THR C . n 
B 2 192 VAL 192 210 210 VAL VAL C . n 
B 2 193 ALA 193 211 211 ALA ALA C . n 
B 2 194 SER 194 212 212 SER SER C . n 
B 2 195 GLU 195 213 213 GLU GLU C . n 
B 2 196 GLY 196 214 214 GLY GLY C . n 
B 2 197 ASP 197 215 215 ASP ASP C . n 
B 2 198 TYR 198 216 216 TYR TYR C . n 
B 2 199 GLY 199 217 217 GLY GLY C . n 
B 2 200 GLU 200 218 218 GLU GLU C . n 
B 2 201 THR 201 219 219 THR THR C . n 
B 2 202 GLY 202 220 220 GLY GLY C . n 
B 2 203 ILE 203 221 221 ILE ILE C . n 
B 2 204 GLU 204 222 222 GLU GLU C . n 
B 2 205 ALA 205 223 223 ALA ALA C . n 
B 2 206 PHE 206 224 224 PHE PHE C . n 
B 2 207 GLU 207 225 225 GLU GLU C . n 
B 2 208 LEU 208 226 226 LEU LEU C . n 
B 2 209 GLU 209 227 227 GLU GLU C . n 
B 2 210 ALA 210 228 228 ALA ALA C . n 
B 2 211 ARG 211 229 229 ARG ARG C . n 
B 2 212 ALA 212 230 230 ALA ALA C . n 
B 2 213 ARG 213 231 231 ARG ARG C . n 
B 2 214 ASN 214 232 232 ASN ASN C . n 
B 2 215 ILE 215 233 233 ILE ILE C . n 
B 2 216 CYS 216 234 234 CYS CYS C . n 
B 2 217 VAL 217 235 235 VAL VAL C . n 
B 2 218 ALA 218 236 236 ALA ALA C . n 
B 2 219 THR 219 237 237 THR THR C . n 
B 2 220 SER 220 238 238 SER SER C . n 
B 2 221 GLU 221 239 239 GLU GLU C . n 
B 2 222 LYS 222 240 240 LYS LYS C . n 
B 2 223 VAL 223 241 241 VAL VAL C . n 
B 2 224 GLY 224 242 242 GLY GLY C . n 
B 2 225 ARG 225 243 243 ARG ARG C . n 
B 2 226 ALA 226 244 244 ALA ALA C . n 
B 2 227 MET 227 245 245 MET MET C . n 
B 2 228 SER 228 246 246 SER SER C . n 
B 2 229 ARG 229 247 247 ARG ARG C . n 
B 2 230 ALA 230 248 248 ALA ALA C . n 
B 2 231 ALA 231 249 249 ALA ALA C . n 
B 2 232 PHE 232 250 250 PHE PHE C . n 
B 2 233 GLU 233 251 251 GLU GLU C . n 
B 2 234 GLY 234 252 252 GLY GLY C . n 
B 2 235 VAL 235 253 253 VAL VAL C . n 
B 2 236 VAL 236 254 254 VAL VAL C . n 
B 2 237 ARG 237 255 255 ARG ARG C . n 
B 2 238 ALA 238 256 256 ALA ALA C . n 
B 2 239 LEU 239 257 257 LEU LEU C . n 
B 2 240 LEU 240 258 258 LEU LEU C . n 
B 2 241 GLN 241 259 259 GLN GLN C . n 
B 2 242 LYS 242 260 260 LYS LYS C . n 
B 2 243 PRO 243 261 261 PRO PRO C . n 
B 2 244 SER 244 262 262 SER SER C . n 
B 2 245 ALA 245 263 263 ALA ALA C . n 
B 2 246 ARG 246 264 264 ARG ARG C . n 
B 2 247 VAL 247 265 265 VAL VAL C . n 
B 2 248 ALA 248 266 266 ALA ALA C . n 
B 2 249 VAL 249 267 267 VAL VAL C . n 
B 2 250 LEU 250 268 268 LEU LEU C . n 
B 2 251 PHE 251 269 269 PHE PHE C . n 
B 2 252 THR 252 270 270 THR THR C . n 
B 2 253 ARG 253 271 271 ARG ARG C . n 
B 2 254 SER 254 272 272 SER SER C . n 
B 2 255 GLU 255 273 273 GLU GLU C . n 
B 2 256 ASP 256 274 274 ASP ASP C . n 
B 2 257 ALA 257 275 275 ALA ALA C . n 
B 2 258 ARG 258 276 276 ARG ARG C . n 
B 2 259 GLU 259 277 277 GLU GLU C . n 
B 2 260 LEU 260 278 278 LEU LEU C . n 
B 2 261 LEU 261 279 279 LEU LEU C . n 
B 2 262 ALA 262 280 280 ALA ALA C . n 
B 2 263 ALA 263 281 281 ALA ALA C . n 
B 2 264 SER 264 282 282 SER SER C . n 
B 2 265 GLN 265 283 283 GLN GLN C . n 
B 2 266 ARG 266 284 284 ARG ARG C . n 
B 2 267 LEU 267 285 285 LEU LEU C . n 
B 2 268 ASN 268 286 286 ASN ASN C . n 
B 2 269 ALA 269 287 287 ALA ALA C . n 
B 2 270 SER 270 288 288 SER SER C . n 
B 2 271 PHE 271 289 289 PHE PHE C . n 
B 2 272 THR 272 290 290 THR THR C . n 
B 2 273 TRP 273 291 291 TRP TRP C . n 
B 2 274 VAL 274 292 292 VAL VAL C . n 
B 2 275 ALA 275 293 293 ALA ALA C . n 
B 2 276 SER 276 294 294 SER SER C . n 
B 2 277 ASP 277 295 295 ASP ASP C . n 
B 2 278 GLY 278 296 296 GLY GLY C . n 
B 2 279 TRP 279 297 297 TRP TRP C . n 
B 2 280 GLY 280 298 298 GLY GLY C . n 
B 2 281 ALA 281 299 299 ALA ALA C . n 
B 2 282 LEU 282 300 300 LEU LEU C . n 
B 2 283 GLU 283 301 301 GLU GLU C . n 
B 2 284 SER 284 302 302 SER SER C . n 
B 2 285 VAL 285 303 303 VAL VAL C . n 
B 2 286 VAL 286 304 304 VAL VAL C . n 
B 2 287 ALA 287 305 305 ALA ALA C . n 
B 2 288 GLY 288 306 306 GLY GLY C . n 
B 2 289 SER 289 307 307 SER SER C . n 
B 2 290 GLU 290 308 308 GLU GLU C . n 
B 2 291 GLY 291 309 309 GLY GLY C . n 
B 2 292 ALA 292 310 310 ALA ALA C . n 
B 2 293 ALA 293 311 311 ALA ALA C . n 
B 2 294 GLU 294 312 312 GLU GLU C . n 
B 2 295 GLY 295 313 313 GLY GLY C . n 
B 2 296 ALA 296 314 314 ALA ALA C . n 
B 2 297 ILE 297 315 315 ILE ILE C . n 
B 2 298 THR 298 316 316 THR THR C . n 
B 2 299 ILE 299 317 317 ILE ILE C . n 
B 2 300 GLU 300 318 318 GLU GLU C . n 
B 2 301 LEU 301 319 319 LEU LEU C . n 
B 2 302 ALA 302 320 320 ALA ALA C . n 
B 2 303 SER 303 321 321 SER SER C . n 
B 2 304 TYR 304 322 322 TYR TYR C . n 
B 2 305 PRO 305 323 323 PRO PRO C . n 
B 2 306 ILE 306 324 324 ILE ILE C . n 
B 2 307 SER 307 325 325 SER SER C . n 
B 2 308 ASP 308 326 326 ASP ASP C . n 
B 2 309 PHE 309 327 327 PHE PHE C . n 
B 2 310 ALA 310 328 328 ALA ALA C . n 
B 2 311 SER 311 329 329 SER SER C . n 
B 2 312 TYR 312 330 330 TYR TYR C . n 
B 2 313 PHE 313 331 331 PHE PHE C . n 
B 2 314 GLN 314 332 332 GLN GLN C . n 
B 2 315 SER 315 333 333 SER SER C . n 
B 2 316 LEU 316 334 334 LEU LEU C . n 
B 2 317 ASP 317 335 335 ASP ASP C . n 
B 2 318 PRO 318 336 336 PRO PRO C . n 
B 2 319 TRP 319 337 337 TRP TRP C . n 
B 2 320 ASN 320 338 338 ASN ASN C . n 
B 2 321 ASN 321 339 339 ASN ASN C . n 
B 2 322 SER 322 340 340 SER SER C . n 
B 2 323 ARG 323 341 341 ARG ARG C . n 
B 2 324 ASN 324 342 342 ASN ASN C . n 
B 2 325 PRO 325 343 343 PRO PRO C . n 
B 2 326 TRP 326 344 344 TRP TRP C . n 
B 2 327 PHE 327 345 345 PHE PHE C . n 
B 2 328 ARG 328 346 346 ARG ARG C . n 
B 2 329 GLU 329 347 347 GLU GLU C . n 
B 2 330 PHE 330 348 348 PHE PHE C . n 
B 2 331 TRP 331 349 349 TRP TRP C . n 
B 2 332 GLU 332 350 350 GLU GLU C . n 
B 2 333 GLN 333 351 351 GLN GLN C . n 
B 2 334 ARG 334 352 352 ARG ARG C . n 
B 2 335 PHE 335 353 353 PHE PHE C . n 
B 2 336 ARG 336 354 354 ARG ARG C . n 
B 2 337 CYS 337 355 355 CYS CYS C . n 
B 2 338 SER 338 356 356 SER SER C . n 
B 2 339 PHE 339 357 357 PHE PHE C . n 
B 2 340 ARG 340 358 358 ARG ARG C . n 
B 2 341 GLN 341 359 359 GLN GLN C . n 
B 2 342 ARG 342 360 360 ARG ARG C . n 
B 2 343 ASP 343 361 361 ASP ASP C . n 
B 2 344 CYS 344 362 362 CYS CYS C . n 
B 2 345 ALA 345 363 363 ALA ALA C . n 
B 2 346 ALA 346 364 364 ALA ALA C . n 
B 2 347 HIS 347 365 365 HIS HIS C . n 
B 2 348 SER 348 366 366 SER SER C . n 
B 2 349 LEU 349 367 367 LEU LEU C . n 
B 2 350 ARG 350 368 368 ARG ARG C . n 
B 2 351 ALA 351 369 369 ALA ALA C . n 
B 2 352 VAL 352 370 370 VAL VAL C . n 
B 2 353 PRO 353 371 371 PRO PRO C . n 
B 2 354 PHE 354 372 372 PHE PHE C . n 
B 2 355 GLU 355 373 373 GLU GLU C . n 
B 2 356 GLN 356 374 374 GLN GLN C . n 
B 2 357 GLU 357 375 375 GLU GLU C . n 
B 2 358 SER 358 376 376 SER SER C . n 
B 2 359 LYS 359 377 377 LYS LYS C . n 
B 2 360 ILE 360 378 378 ILE ILE C . n 
B 2 361 MET 361 379 379 MET MET C . n 
B 2 362 PHE 362 380 380 PHE PHE C . n 
B 2 363 VAL 363 381 381 VAL VAL C . n 
B 2 364 VAL 364 382 382 VAL VAL C . n 
B 2 365 ASN 365 383 383 ASN ASN C . n 
B 2 366 ALA 366 384 384 ALA ALA C . n 
B 2 367 VAL 367 385 385 VAL VAL C . n 
B 2 368 TYR 368 386 386 TYR TYR C . n 
B 2 369 ALA 369 387 387 ALA ALA C . n 
B 2 370 MET 370 388 388 MET MET C . n 
B 2 371 ALA 371 389 389 ALA ALA C . n 
B 2 372 HIS 372 390 390 HIS HIS C . n 
B 2 373 ALA 373 391 391 ALA ALA C . n 
B 2 374 LEU 374 392 392 LEU LEU C . n 
B 2 375 HIS 375 393 393 HIS HIS C . n 
B 2 376 ASN 376 394 394 ASN ASN C . n 
B 2 377 MET 377 395 395 MET MET C . n 
B 2 378 HIS 378 396 396 HIS HIS C . n 
B 2 379 ARG 379 397 397 ARG ARG C . n 
B 2 380 ALA 380 398 398 ALA ALA C . n 
B 2 381 LEU 381 399 399 LEU LEU C . n 
B 2 382 CYS 382 400 400 CYS CYS C . n 
B 2 383 PRO 383 401 401 PRO PRO C . n 
B 2 384 ASN 384 402 402 ASN ASN C . n 
B 2 385 THR 385 403 403 THR THR C . n 
B 2 386 THR 386 404 404 THR THR C . n 
B 2 387 ARG 387 405 405 ARG ARG C . n 
B 2 388 LEU 388 406 406 LEU LEU C . n 
B 2 389 CYS 389 407 407 CYS CYS C . n 
B 2 390 ASP 390 408 408 ASP ASP C . n 
B 2 391 ALA 391 409 409 ALA ALA C . n 
B 2 392 MET 392 410 410 MET MET C . n 
B 2 393 ARG 393 411 411 ARG ARG C . n 
B 2 394 PRO 394 412 412 PRO PRO C . n 
B 2 395 VAL 395 413 413 VAL VAL C . n 
B 2 396 ASN 396 414 414 ASN ASN C . n 
B 2 397 GLY 397 415 415 GLY GLY C . n 
B 2 398 ARG 398 416 416 ARG ARG C . n 
B 2 399 ARG 399 417 417 ARG ARG C . n 
B 2 400 LEU 400 418 418 LEU LEU C . n 
B 2 401 TYR 401 419 419 TYR TYR C . n 
B 2 402 LYS 402 420 420 LYS LYS C . n 
B 2 403 ASP 403 421 421 ASP ASP C . n 
B 2 404 PHE 404 422 422 PHE PHE C . n 
B 2 405 VAL 405 423 423 VAL VAL C . n 
B 2 406 LEU 406 424 424 LEU LEU C . n 
B 2 407 ASN 407 425 425 ASN ASN C . n 
B 2 408 VAL 408 426 426 VAL VAL C . n 
B 2 409 LYS 409 427 427 LYS LYS C . n 
B 2 410 PHE 410 428 428 PHE PHE C . n 
B 2 411 ASP 411 429 429 ASP ASP C . n 
B 2 412 ALA 412 430 430 ALA ALA C . n 
B 2 413 PRO 413 431 431 PRO PRO C . n 
B 2 414 PHE 414 432 432 PHE PHE C . n 
B 2 415 ARG 415 433 433 ARG ARG C . n 
B 2 416 PRO 416 434 434 PRO PRO C . n 
B 2 417 ALA 417 435 435 ALA ALA C . n 
B 2 418 ASP 418 436 436 ASP ASP C . n 
B 2 419 THR 419 437 437 THR THR C . n 
B 2 420 HIS 420 438 438 HIS HIS C . n 
B 2 421 ASN 421 439 439 ASN ASN C . n 
B 2 422 GLU 422 440 440 GLU GLU C . n 
B 2 423 VAL 423 441 441 VAL VAL C . n 
B 2 424 ARG 424 442 442 ARG ARG C . n 
B 2 425 PHE 425 443 443 PHE PHE C . n 
B 2 426 ASP 426 444 444 ASP ASP C . n 
B 2 427 ARG 427 445 445 ARG ARG C . n 
B 2 428 PHE 428 446 446 PHE PHE C . n 
B 2 429 GLY 429 447 447 GLY GLY C . n 
B 2 430 ASP 430 448 448 ASP ASP C . n 
B 2 431 GLY 431 449 449 GLY GLY C . n 
B 2 432 ILE 432 450 450 ILE ILE C . n 
B 2 433 GLY 433 451 451 GLY GLY C . n 
B 2 434 ARG 434 452 452 ARG ARG C . n 
B 2 435 TYR 435 453 453 TYR TYR C . n 
B 2 436 ASN 436 454 454 ASN ASN C . n 
B 2 437 ILE 437 455 455 ILE ILE C . n 
B 2 438 PHE 438 456 456 PHE PHE C . n 
B 2 439 THR 439 457 457 THR THR C . n 
B 2 440 TYR 440 458 458 TYR TYR C . n 
B 2 441 LEU 441 459 459 LEU LEU C . n 
B 2 442 ARG 442 460 460 ARG ARG C . n 
B 2 443 ALA 443 461 461 ALA ALA C . n 
B 2 444 GLY 444 462 462 GLY GLY C . n 
B 2 445 SER 445 463 463 SER SER C . n 
B 2 446 GLY 446 464 464 GLY GLY C . n 
B 2 447 ARG 447 465 465 ARG ARG C . n 
B 2 448 TYR 448 466 466 TYR TYR C . n 
B 2 449 ARG 449 467 467 ARG ARG C . n 
B 2 450 TYR 450 468 468 TYR TYR C . n 
B 2 451 GLN 451 469 469 GLN GLN C . n 
B 2 452 LYS 452 470 470 LYS LYS C . n 
B 2 453 VAL 453 471 471 VAL VAL C . n 
B 2 454 GLY 454 472 472 GLY GLY C . n 
B 2 455 TYR 455 473 473 TYR TYR C . n 
B 2 456 TRP 456 474 474 TRP TRP C . n 
B 2 457 ALA 457 475 475 ALA ALA C . n 
B 2 458 GLU 458 476 476 GLU GLU C . n 
B 2 459 GLY 459 477 477 GLY GLY C . n 
B 2 460 LEU 460 478 478 LEU LEU C . n 
B 2 461 THR 461 479 479 THR THR C . n 
B 2 462 LEU 462 480 480 LEU LEU C . n 
B 2 463 ASP 463 481 481 ASP ASP C . n 
B 2 464 THR 464 482 482 THR THR C . n 
B 2 465 SER 465 483 483 SER SER C . n 
B 2 466 LEU 466 484 484 LEU LEU C . n 
B 2 467 ILE 467 485 485 ILE ILE C . n 
B 2 468 PRO 468 486 486 PRO PRO C . n 
B 2 469 TRP 469 487 487 TRP TRP C . n 
B 2 470 ALA 470 488 488 ALA ALA C . n 
B 2 471 SER 471 489 489 SER SER C . n 
B 2 472 PRO 472 490 490 PRO PRO C . n 
B 2 473 SER 473 491 491 SER SER C . n 
B 2 474 ALA 474 492 492 ALA ALA C . n 
B 2 475 GLY 475 493 493 GLY GLY C . n 
B 2 476 PRO 476 494 494 PRO PRO C . n 
B 2 477 LEU 477 495 495 LEU LEU C . n 
B 2 478 PRO 478 496 496 PRO PRO C . n 
B 2 479 ALA 479 497 497 ALA ALA C . n 
B 2 480 SER 480 498 498 SER SER C . n 
B 2 481 ARG 481 499 499 ARG ARG C . n 
B 2 482 CYS 482 500 500 CYS CYS C . n 
B 2 483 SER 483 501 501 SER SER C . n 
B 2 484 GLU 484 502 502 GLU GLU C . n 
B 2 485 PRO 485 503 503 PRO PRO C . n 
B 2 486 CYS 486 504 504 CYS CYS C . n 
B 2 487 LEU 487 505 505 LEU LEU C . n 
B 2 488 GLN 488 506 506 GLN GLN C . n 
B 2 489 ASN 489 507 507 ASN ASN C . n 
B 2 490 GLU 490 508 508 GLU GLU C . n 
B 2 491 VAL 491 509 509 VAL VAL C . n 
B 2 492 LYS 492 510 510 LYS LYS C . n 
B 2 493 SER 493 511 511 SER SER C . n 
B 2 494 VAL 494 512 512 VAL VAL C . n 
B 2 495 GLN 495 513 513 GLN GLN C . n 
B 2 496 PRO 496 514 514 PRO PRO C . n 
B 2 497 GLY 497 515 515 GLY GLY C . n 
B 2 498 GLU 498 516 516 GLU GLU C . n 
B 2 499 VAL 499 517 517 VAL VAL C . n 
B 2 500 CYS 500 518 518 CYS CYS C . n 
B 2 501 CYS 501 519 519 CYS CYS C . n 
B 2 502 TRP 502 520 520 TRP TRP C . n 
B 2 503 LEU 503 521 521 LEU LEU C . n 
B 2 504 CYS 504 522 522 CYS CYS C . n 
B 2 505 ILE 505 523 523 ILE ILE C . n 
B 2 506 PRO 506 524 524 PRO PRO C . n 
B 2 507 CYS 507 525 525 CYS CYS C . n 
B 2 508 GLN 508 526 526 GLN GLN C . n 
B 2 509 PRO 509 527 527 PRO PRO C . n 
B 2 510 TYR 510 528 528 TYR TYR C . n 
B 2 511 GLU 511 529 529 GLU GLU C . n 
B 2 512 TYR 512 530 530 TYR TYR C . n 
B 2 513 ARG 513 531 531 ARG ARG C . n 
B 2 514 LEU 514 532 532 LEU LEU C . n 
B 2 515 ASP 515 533 533 ASP ASP C . n 
B 2 516 GLU 516 534 534 GLU GLU C . n 
B 2 517 PHE 517 535 535 PHE PHE C . n 
B 2 518 THR 518 536 536 THR THR C . n 
B 2 519 CYS 519 537 537 CYS CYS C . n 
B 2 520 ALA 520 538 538 ALA ALA C . n 
B 2 521 ASP 521 539 539 ASP ASP C . n 
B 2 522 CYS 522 540 540 CYS CYS C . n 
B 2 523 GLY 523 541 541 GLY GLY C . n 
B 2 524 LEU 524 542 542 LEU LEU C . n 
B 2 525 GLY 525 543 543 GLY GLY C . n 
B 2 526 TYR 526 544 544 TYR TYR C . n 
B 2 527 TRP 527 545 545 TRP TRP C . n 
B 2 528 PRO 528 546 546 PRO PRO C . n 
B 2 529 ASN 529 547 547 ASN ASN C . n 
B 2 530 ALA 530 548 548 ALA ALA C . n 
B 2 531 SER 531 549 ?   ?   ?   C . n 
B 2 532 LEU 532 550 ?   ?   ?   C . n 
B 2 533 THR 533 551 ?   ?   ?   C . n 
B 2 534 GLY 534 552 ?   ?   ?   C . n 
B 2 535 CYS 535 553 ?   ?   ?   C . n 
B 2 536 PHE 536 554 ?   ?   ?   C . n 
B 2 537 GLU 537 555 ?   ?   ?   C . n 
B 2 538 LEU 538 556 ?   ?   ?   C . n 
B 2 539 PRO 539 557 ?   ?   ?   C . n 
B 2 540 GLN 540 558 ?   ?   ?   C . n 
B 2 541 GLU 541 559 ?   ?   ?   C . n 
B 2 542 TYR 542 560 ?   ?   ?   C . n 
B 2 543 ILE 543 561 ?   ?   ?   C . n 
B 2 544 ARG 544 562 ?   ?   ?   C . n 
B 2 545 TRP 545 563 ?   ?   ?   C . n 
B 2 546 GLY 546 564 ?   ?   ?   C . n 
B 2 547 ASP 547 565 565 ASP ASP C . n 
B 2 548 ALA 548 566 566 ALA ALA C . n 
B 2 549 TRP 549 567 567 TRP TRP C . n 
B 2 550 ALA 550 568 568 ALA ALA C . n 
B 2 551 VAL 551 569 569 VAL VAL C . n 
B 2 552 GLY 552 570 570 GLY GLY C . n 
B 2 553 PRO 553 571 571 PRO PRO C . n 
B 2 554 VAL 554 572 572 VAL VAL C . n 
B 2 555 THR 555 573 573 THR THR C . n 
B 2 556 ILE 556 574 574 ILE ILE C . n 
B 2 557 ALA 557 575 575 ALA ALA C . n 
B 2 558 CYS 558 576 576 CYS CYS C . n 
B 2 559 LEU 559 577 577 LEU LEU C . n 
B 2 560 GLY 560 578 578 GLY GLY C . n 
B 2 561 ALA 561 579 579 ALA ALA C . n 
B 2 562 LEU 562 580 580 LEU LEU C . n 
B 2 563 ALA 563 581 581 ALA ALA C . n 
B 2 564 THR 564 582 582 THR THR C . n 
B 2 565 LEU 565 583 583 LEU LEU C . n 
B 2 566 PHE 566 584 584 PHE PHE C . n 
B 2 567 VAL 567 585 585 VAL VAL C . n 
B 2 568 LEU 568 586 586 LEU LEU C . n 
B 2 569 GLY 569 587 587 GLY GLY C . n 
B 2 570 VAL 570 588 588 VAL VAL C . n 
B 2 571 PHE 571 589 589 PHE PHE C . n 
B 2 572 VAL 572 590 590 VAL VAL C . n 
B 2 573 ARG 573 591 591 ARG ARG C . n 
B 2 574 HIS 574 592 592 HIS HIS C . n 
B 2 575 ASN 575 593 593 ASN ASN C . n 
B 2 576 ALA 576 594 594 ALA ALA C . n 
B 2 577 THR 577 595 595 THR THR C . n 
B 2 578 PRO 578 596 596 PRO PRO C . n 
B 2 579 VAL 579 597 597 VAL VAL C . n 
B 2 580 VAL 580 598 598 VAL VAL C . n 
B 2 581 LYS 581 599 599 LYS LYS C . n 
B 2 582 ALA 582 600 600 ALA ALA C . n 
B 2 583 SER 583 601 601 SER SER C . n 
B 2 584 GLY 584 602 602 GLY GLY C . n 
B 2 585 ARG 585 603 603 ARG ARG C . n 
B 2 586 GLU 586 604 604 GLU GLU C . n 
B 2 587 LEU 587 605 605 LEU LEU C . n 
B 2 588 CYS 588 606 606 CYS CYS C . n 
B 2 589 TYR 589 607 607 TYR TYR C . n 
B 2 590 ILE 590 608 608 ILE ILE C . n 
B 2 591 LEU 591 609 609 LEU LEU C . n 
B 2 592 LEU 592 610 610 LEU LEU C . n 
B 2 593 GLY 593 611 611 GLY GLY C . n 
B 2 594 GLY 594 612 612 GLY GLY C . n 
B 2 595 VAL 595 613 613 VAL VAL C . n 
B 2 596 PHE 596 614 614 PHE PHE C . n 
B 2 597 LEU 597 615 615 LEU LEU C . n 
B 2 598 CYS 598 616 616 CYS CYS C . n 
B 2 599 TYR 599 617 617 TYR TYR C . n 
B 2 600 CYS 600 618 618 CYS CYS C . n 
B 2 601 MET 601 619 619 MET MET C . n 
B 2 602 THR 602 620 620 THR THR C . n 
B 2 603 PHE 603 621 621 PHE PHE C . n 
B 2 604 ILE 604 622 622 ILE ILE C . n 
B 2 605 PHE 605 623 623 PHE PHE C . n 
B 2 606 ILE 606 624 624 ILE ILE C . n 
B 2 607 ALA 607 625 625 ALA ALA C . n 
B 2 608 LYS 608 626 626 LYS LYS C . n 
B 2 609 PRO 609 627 627 PRO PRO C . n 
B 2 610 SER 610 628 628 SER SER C . n 
B 2 611 THR 611 629 629 THR THR C . n 
B 2 612 ALA 612 630 630 ALA ALA C . n 
B 2 613 VAL 613 631 631 VAL VAL C . n 
B 2 614 CYS 614 632 632 CYS CYS C . n 
B 2 615 THR 615 633 633 THR THR C . n 
B 2 616 LEU 616 634 634 LEU LEU C . n 
B 2 617 ARG 617 635 635 ARG ARG C . n 
B 2 618 ARG 618 636 636 ARG ARG C . n 
B 2 619 LEU 619 637 637 LEU LEU C . n 
B 2 620 GLY 620 638 638 GLY GLY C . n 
B 2 621 LEU 621 639 639 LEU LEU C . n 
B 2 622 GLY 622 640 640 GLY GLY C . n 
B 2 623 THR 623 641 641 THR THR C . n 
B 2 624 ALA 624 642 642 ALA ALA C . n 
B 2 625 PHE 625 643 643 PHE PHE C . n 
B 2 626 SER 626 644 644 SER SER C . n 
B 2 627 VAL 627 645 645 VAL VAL C . n 
B 2 628 CYS 628 646 646 CYS CYS C . n 
B 2 629 TYR 629 647 647 TYR TYR C . n 
B 2 630 SER 630 648 648 SER SER C . n 
B 2 631 ALA 631 649 649 ALA ALA C . n 
B 2 632 LEU 632 650 650 LEU LEU C . n 
B 2 633 LEU 633 651 651 LEU LEU C . n 
B 2 634 THR 634 652 652 THR THR C . n 
B 2 635 LYS 635 653 653 LYS LYS C . n 
B 2 636 THR 636 654 654 THR THR C . n 
B 2 637 ASN 637 655 655 ASN ASN C . n 
B 2 638 ARG 638 656 656 ARG ARG C . n 
B 2 639 ILE 639 657 657 ILE ILE C . n 
B 2 640 ALA 640 658 658 ALA ALA C . n 
B 2 641 ARG 641 659 ?   ?   ?   C . n 
B 2 642 ILE 642 660 ?   ?   ?   C . n 
B 2 643 PHE 643 661 ?   ?   ?   C . n 
B 2 644 GLY 644 662 ?   ?   ?   C . n 
B 2 645 GLY 645 663 ?   ?   ?   C . n 
B 2 646 ALA 646 664 ?   ?   ?   C . n 
B 2 647 ARG 647 665 ?   ?   ?   C . n 
B 2 648 GLU 648 666 ?   ?   ?   C . n 
B 2 649 GLY 649 667 ?   ?   ?   C . n 
B 2 650 ALA 650 668 ?   ?   ?   C . n 
B 2 651 GLN 651 669 ?   ?   ?   C . n 
B 2 652 ARG 652 670 ?   ?   ?   C . n 
B 2 653 PRO 653 671 ?   ?   ?   C . n 
B 2 654 ARG 654 672 ?   ?   ?   C . n 
B 2 655 PHE 655 673 ?   ?   ?   C . n 
B 2 656 ILE 656 674 674 ILE ILE C . n 
B 2 657 SER 657 675 675 SER SER C . n 
B 2 658 PRO 658 676 676 PRO PRO C . n 
B 2 659 ALA 659 677 677 ALA ALA C . n 
B 2 660 SER 660 678 678 SER SER C . n 
B 2 661 GLN 661 679 679 GLN GLN C . n 
B 2 662 VAL 662 680 680 VAL VAL C . n 
B 2 663 ALA 663 681 681 ALA ALA C . n 
B 2 664 ILE 664 682 682 ILE ILE C . n 
B 2 665 CYS 665 683 683 CYS CYS C . n 
B 2 666 LEU 666 684 684 LEU LEU C . n 
B 2 667 ALA 667 685 685 ALA ALA C . n 
B 2 668 LEU 668 686 686 LEU LEU C . n 
B 2 669 ILE 669 687 687 ILE ILE C . n 
B 2 670 SER 670 688 688 SER SER C . n 
B 2 671 GLY 671 689 689 GLY GLY C . n 
B 2 672 GLN 672 690 690 GLN GLN C . n 
B 2 673 LEU 673 691 691 LEU LEU C . n 
B 2 674 LEU 674 692 692 LEU LEU C . n 
B 2 675 ILE 675 693 693 ILE ILE C . n 
B 2 676 VAL 676 694 694 VAL VAL C . n 
B 2 677 VAL 677 695 695 VAL VAL C . n 
B 2 678 ALA 678 696 696 ALA ALA C . n 
B 2 679 TRP 679 697 697 TRP TRP C . n 
B 2 680 LEU 680 698 698 LEU LEU C . n 
B 2 681 VAL 681 699 699 VAL VAL C . n 
B 2 682 VAL 682 700 700 VAL VAL C . n 
B 2 683 GLU 683 701 701 GLU GLU C . n 
B 2 684 ALA 684 702 702 ALA ALA C . n 
B 2 685 PRO 685 703 703 PRO PRO C . n 
B 2 686 GLY 686 704 704 GLY GLY C . n 
B 2 687 THR 687 705 705 THR THR C . n 
B 2 688 GLY 688 706 706 GLY GLY C . n 
B 2 689 LYS 689 707 707 LYS LYS C . n 
B 2 690 GLU 690 708 708 GLU GLU C . n 
B 2 691 THR 691 709 709 THR THR C . n 
B 2 692 ALA 692 710 710 ALA ALA C . n 
B 2 693 PRO 693 711 711 PRO PRO C . n 
B 2 694 GLU 694 712 712 GLU GLU C . n 
B 2 695 ARG 695 713 713 ARG ARG C . n 
B 2 696 ARG 696 714 714 ARG ARG C . n 
B 2 697 GLU 697 715 715 GLU GLU C . n 
B 2 698 VAL 698 716 716 VAL VAL C . n 
B 2 699 VAL 699 717 717 VAL VAL C . n 
B 2 700 THR 700 718 718 THR THR C . n 
B 2 701 LEU 701 719 719 LEU LEU C . n 
B 2 702 ARG 702 720 720 ARG ARG C . n 
B 2 703 CYS 703 721 721 CYS CYS C . n 
B 2 704 ASN 704 722 722 ASN ASN C . n 
B 2 705 HIS 705 723 723 HIS HIS C . n 
B 2 706 ARG 706 724 724 ARG ARG C . n 
B 2 707 ASP 707 725 725 ASP ASP C . n 
B 2 708 ALA 708 726 726 ALA ALA C . n 
B 2 709 SER 709 727 727 SER SER C . n 
B 2 710 MET 710 728 728 MET MET C . n 
B 2 711 LEU 711 729 729 LEU LEU C . n 
B 2 712 GLY 712 730 730 GLY GLY C . n 
B 2 713 SER 713 731 731 SER SER C . n 
B 2 714 LEU 714 732 732 LEU LEU C . n 
B 2 715 ALA 715 733 733 ALA ALA C . n 
B 2 716 TYR 716 734 734 TYR TYR C . n 
B 2 717 ASN 717 735 735 ASN ASN C . n 
B 2 718 VAL 718 736 736 VAL VAL C . n 
B 2 719 LEU 719 737 737 LEU LEU C . n 
B 2 720 LEU 720 738 738 LEU LEU C . n 
B 2 721 ILE 721 739 739 ILE ILE C . n 
B 2 722 ALA 722 740 740 ALA ALA C . n 
B 2 723 LEU 723 741 741 LEU LEU C . n 
B 2 724 CYS 724 742 742 CYS CYS C . n 
B 2 725 THR 725 743 743 THR THR C . n 
B 2 726 LEU 726 744 744 LEU LEU C . n 
B 2 727 TYR 727 745 745 TYR TYR C . n 
B 2 728 ALA 728 746 746 ALA ALA C . n 
B 2 729 PHE 729 747 747 PHE PHE C . n 
B 2 730 LYS 730 748 748 LYS LYS C . n 
B 2 731 THR 731 749 749 THR THR C . n 
B 2 732 ARG 732 750 750 ARG ARG C . n 
B 2 733 LYS 733 751 751 LYS LYS C . n 
B 2 734 CYS 734 752 752 CYS CYS C . n 
B 2 735 PRO 735 753 753 PRO PRO C . n 
B 2 736 GLU 736 754 754 GLU GLU C . n 
B 2 737 ASN 737 755 755 ASN ASN C . n 
B 2 738 PHE 738 756 756 PHE PHE C . n 
B 2 739 ASN 739 757 757 ASN ASN C . n 
B 2 740 GLU 740 758 758 GLU GLU C . n 
B 2 741 ALA 741 759 759 ALA ALA C . n 
B 2 742 LYS 742 760 760 LYS LYS C . n 
B 2 743 PHE 743 761 761 PHE PHE C . n 
B 2 744 ILE 744 762 762 ILE ILE C . n 
B 2 745 GLY 745 763 763 GLY GLY C . n 
B 2 746 PHE 746 764 764 PHE PHE C . n 
B 2 747 THR 747 765 765 THR THR C . n 
B 2 748 MET 748 766 766 MET MET C . n 
B 2 749 TYR 749 767 767 TYR TYR C . n 
B 2 750 THR 750 768 768 THR THR C . n 
B 2 751 THR 751 769 769 THR THR C . n 
B 2 752 CYS 752 770 770 CYS CYS C . n 
B 2 753 ILE 753 771 771 ILE ILE C . n 
B 2 754 ILE 754 772 772 ILE ILE C . n 
B 2 755 TRP 755 773 773 TRP TRP C . n 
B 2 756 LEU 756 774 774 LEU LEU C . n 
B 2 757 ALA 757 775 775 ALA ALA C . n 
B 2 758 PHE 758 776 776 PHE PHE C . n 
B 2 759 LEU 759 777 777 LEU LEU C . n 
B 2 760 PRO 760 778 778 PRO PRO C . n 
B 2 761 ILE 761 779 779 ILE ILE C . n 
B 2 762 PHE 762 780 780 PHE PHE C . n 
B 2 763 TYR 763 781 781 TYR TYR C . n 
B 2 764 VAL 764 782 782 VAL VAL C . n 
B 2 765 THR 765 783 783 THR THR C . n 
B 2 766 SER 766 784 784 SER SER C . n 
B 2 767 SER 767 785 785 SER SER C . n 
B 2 768 ASP 768 786 786 ASP ASP C . n 
B 2 769 TYR 769 787 787 TYR TYR C . n 
B 2 770 ARG 770 788 788 ARG ARG C . n 
B 2 771 VAL 771 789 789 VAL VAL C . n 
B 2 772 GLN 772 790 790 GLN GLN C . n 
B 2 773 THR 773 791 791 THR THR C . n 
B 2 774 THR 774 792 792 THR THR C . n 
B 2 775 THR 775 793 793 THR THR C . n 
B 2 776 MET 776 794 794 MET MET C . n 
B 2 777 CYS 777 795 795 CYS CYS C . n 
B 2 778 VAL 778 796 796 VAL VAL C . n 
B 2 779 SER 779 797 797 SER SER C . n 
B 2 780 VAL 780 798 798 VAL VAL C . n 
B 2 781 SER 781 799 799 SER SER C . n 
B 2 782 LEU 782 800 800 LEU LEU C . n 
B 2 783 SER 783 801 801 SER SER C . n 
B 2 784 GLY 784 802 802 GLY GLY C . n 
B 2 785 SER 785 803 803 SER SER C . n 
B 2 786 VAL 786 804 804 VAL VAL C . n 
B 2 787 VAL 787 805 805 VAL VAL C . n 
B 2 788 LEU 788 806 806 LEU LEU C . n 
B 2 789 GLY 789 807 807 GLY GLY C . n 
B 2 790 CYS 790 808 808 CYS CYS C . n 
B 2 791 LEU 791 809 809 LEU LEU C . n 
B 2 792 PHE 792 810 810 PHE PHE C . n 
B 2 793 ALA 793 811 811 ALA ALA C . n 
B 2 794 PRO 794 812 812 PRO PRO C . n 
B 2 795 LYS 795 813 813 LYS LYS C . n 
B 2 796 LEU 796 814 814 LEU LEU C . n 
B 2 797 HIS 797 815 815 HIS HIS C . n 
B 2 798 ILE 798 816 816 ILE ILE C . n 
B 2 799 ILE 799 817 817 ILE ILE C . n 
B 2 800 LEU 800 818 818 LEU LEU C . n 
B 2 801 PHE 801 819 819 PHE PHE C . n 
B 2 802 GLN 802 820 820 GLN GLN C . n 
B 2 803 PRO 803 821 ?   ?   ?   C . n 
B 2 804 GLN 804 822 ?   ?   ?   C . n 
B 2 805 LYS 805 823 ?   ?   ?   C . n 
B 2 806 ASN 806 824 ?   ?   ?   C . n 
B 2 807 VAL 807 825 ?   ?   ?   C . n 
B 2 808 VAL 808 826 ?   ?   ?   C . n 
B 2 809 SER 809 827 ?   ?   ?   C . n 
B 2 810 HIS 810 828 ?   ?   ?   C . n 
B 2 811 ARG 811 829 ?   ?   ?   C . n 
B 2 812 ALA 812 830 ?   ?   ?   C . n 
B 2 813 PRO 813 831 ?   ?   ?   C . n 
B 2 814 THR 814 832 ?   ?   ?   C . n 
B 2 815 SER 815 833 ?   ?   ?   C . n 
B 2 816 ARG 816 834 ?   ?   ?   C . n 
B 2 817 PHE 817 835 ?   ?   ?   C . n 
B 2 818 GLY 818 836 ?   ?   ?   C . n 
B 2 819 SER 819 837 ?   ?   ?   C . n 
B 2 820 ALA 820 838 ?   ?   ?   C . n 
B 2 821 ALA 821 839 ?   ?   ?   C . n 
B 2 822 ALA 822 840 ?   ?   ?   C . n 
B 2 823 ARG 823 841 ?   ?   ?   C . n 
B 2 824 ALA 824 842 ?   ?   ?   C . n 
B 2 825 SER 825 843 ?   ?   ?   C . n 
B 2 826 SER 826 844 ?   ?   ?   C . n 
B 2 827 SER 827 845 ?   ?   ?   C . n 
B 2 828 LEU 828 846 ?   ?   ?   C . n 
B 2 829 GLY 829 847 ?   ?   ?   C . n 
B 2 830 GLN 830 848 ?   ?   ?   C . n 
B 2 831 GLY 831 849 ?   ?   ?   C . n 
B 2 832 SER 832 850 ?   ?   ?   C . n 
B 2 833 GLY 833 851 ?   ?   ?   C . n 
B 2 834 SER 834 852 ?   ?   ?   C . n 
B 2 835 GLN 835 853 ?   ?   ?   C . n 
B 2 836 PHE 836 854 ?   ?   ?   C . n 
B 2 837 VAL 837 855 ?   ?   ?   C . n 
B 2 838 PRO 838 856 ?   ?   ?   C . n 
B 2 839 THR 839 857 ?   ?   ?   C . n 
B 2 840 VAL 840 858 ?   ?   ?   C . n 
B 2 841 CYS 841 859 ?   ?   ?   C . n 
B 2 842 ASN 842 860 ?   ?   ?   C . n 
B 2 843 GLY 843 861 ?   ?   ?   C . n 
B 2 844 ARG 844 862 ?   ?   ?   C . n 
B 2 845 GLU 845 863 ?   ?   ?   C . n 
B 2 846 VAL 846 864 ?   ?   ?   C . n 
B 2 847 VAL 847 865 ?   ?   ?   C . n 
B 2 848 ASP 848 866 ?   ?   ?   C . n 
B 2 849 SER 849 867 ?   ?   ?   C . n 
B 2 850 THR 850 868 ?   ?   ?   C . n 
B 2 851 THR 851 869 ?   ?   ?   C . n 
B 2 852 SER 852 870 ?   ?   ?   C . n 
B 2 853 SER 853 871 ?   ?   ?   C . n 
B 2 854 LEU 854 872 ?   ?   ?   C . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        E7P 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   E7P 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
_pdbx_nonpoly_scheme.asym_id         C 
_pdbx_nonpoly_scheme.entity_id       3 
_pdbx_nonpoly_scheme.mon_id          E7P 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     1001 
_pdbx_nonpoly_scheme.auth_seq_num    1 
_pdbx_nonpoly_scheme.pdb_mon_id      E7P 
_pdbx_nonpoly_scheme.auth_mon_id     LAP 
_pdbx_nonpoly_scheme.pdb_strand_id   B 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 B LYS 74  ? CG  ? A LYS 42  CG  
2  1 Y 1 B LYS 74  ? CD  ? A LYS 42  CD  
3  1 Y 1 B LYS 74  ? CE  ? A LYS 42  CE  
4  1 Y 1 B LYS 74  ? NZ  ? A LYS 42  NZ  
5  1 Y 1 B ARG 78  ? CG  ? A ARG 46  CG  
6  1 Y 1 B ARG 78  ? CD  ? A ARG 46  CD  
7  1 Y 1 B ARG 78  ? NE  ? A ARG 46  NE  
8  1 Y 1 B ARG 78  ? CZ  ? A ARG 46  CZ  
9  1 Y 1 B ARG 78  ? NH1 ? A ARG 46  NH1 
10 1 Y 1 B ARG 78  ? NH2 ? A ARG 46  NH2 
11 1 Y 1 B ARG 111 ? CG  ? A ARG 79  CG  
12 1 Y 1 B ARG 111 ? CD  ? A ARG 79  CD  
13 1 Y 1 B ARG 111 ? NE  ? A ARG 79  NE  
14 1 Y 1 B ARG 111 ? CZ  ? A ARG 79  CZ  
15 1 Y 1 B ARG 111 ? NH1 ? A ARG 79  NH1 
16 1 Y 1 B ARG 111 ? NH2 ? A ARG 79  NH2 
17 1 Y 1 B ASP 112 ? CG  ? A ASP 80  CG  
18 1 Y 1 B ASP 112 ? OD1 ? A ASP 80  OD1 
19 1 Y 1 B ASP 112 ? OD2 ? A ASP 80  OD2 
20 1 Y 1 B LYS 405 ? CG  ? A LYS 373 CG  
21 1 Y 1 B LYS 405 ? CD  ? A LYS 373 CD  
22 1 Y 1 B LYS 405 ? CE  ? A LYS 373 CE  
23 1 Y 1 B LYS 405 ? NZ  ? A LYS 373 NZ  
24 1 Y 1 C TRP 204 ? CG  ? B TRP 186 CG  
25 1 Y 1 C TRP 204 ? CD1 ? B TRP 186 CD1 
26 1 Y 1 C TRP 204 ? CD2 ? B TRP 186 CD2 
27 1 Y 1 C TRP 204 ? NE1 ? B TRP 186 NE1 
28 1 Y 1 C TRP 204 ? CE2 ? B TRP 186 CE2 
29 1 Y 1 C TRP 204 ? CE3 ? B TRP 186 CE3 
30 1 Y 1 C TRP 204 ? CZ2 ? B TRP 186 CZ2 
31 1 Y 1 C TRP 204 ? CZ3 ? B TRP 186 CZ3 
32 1 Y 1 C TRP 204 ? CH2 ? B TRP 186 CH2 
33 1 Y 1 C ARG 531 ? CG  ? B ARG 513 CG  
34 1 Y 1 C ARG 531 ? CD  ? B ARG 513 CD  
35 1 Y 1 C ARG 531 ? NE  ? B ARG 513 NE  
36 1 Y 1 C ARG 531 ? CZ  ? B ARG 513 CZ  
37 1 Y 1 C ARG 531 ? NH1 ? B ARG 513 NH1 
38 1 Y 1 C ARG 531 ? NH2 ? B ARG 513 NH2 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8WG9 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     8WG9 
_struct.title                        'mGlu2-mGlu4 heterodimer bound mGlu4 agonist E7P' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8WG9 
_struct_keywords.text            'GPCR, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP GRM4_HUMAN Q14833 ? 1 
;KPKGHPHMNSIRIDGDITLGGLFPVHGRGSEGKPCGELKKEKGIHRLEAMLFALDRINNDPDLLPNITLGARILDTCSRD
THALEQSLTFVQALIEKDGTEVRCGSGGPPIITKPERVVGVIGASGSSVSIMVANILRLFKIPQISYASTAPDLSDNSRY
DFFSRVVPSDTYQAQAMVDIVRALKWNYVSTVASEGSYGESGVEAFIQKSREDGGVCIAQSVKIPREPKAGEFDKIIRRL
LETSNARAVIIFANEDDIRRVLEAARRANQTGHFFWMGSDSWGSKIAPVLHLEEVAEGAVTILPKRMSVRGFDRYFSSRT
LDNNRRNIWFAEFWEDNFHCKLSRHALKKGSHVKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHALHAMHRDLCPGRV
GLCPRMDPVDGTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQYQLRNDSAEYKVIGSWTDHLHLRIERMHWPGSG
QQLPRSICSLPCQPGERKKTVKGMPCCWHCEPCTGYQYQVDRYTCKTCPYDMRPTENRTGCRPIPIIKLEWGSPWAVLPL
FLAVVGIAATLFVVITFVRYNDTPIVKASGRELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLGLGMSISYAALLT
KTNRIYRIFEQGKRSVSAPRFISPASQLAITFSLISLQLLGICVWFVVDPSHSVVDFQDQRTLDPRFARGVLKCDISDLS
LICLLGYSMLLMVTCTVYAIKTRGVPETFNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSADKLYIQTTTLTVSVSLSASV
SLGMLYMPKVYIILFHPEQNVPKRKRSLKAVVTAATMSNKFTQKGNFRPNGEAKSELCENLEAPALATKQTYVTYTNHAI

;
33 
2 UNP GRM2_HUMAN Q14416 ? 2 
;EGPAKKVLTLEGDLVLGGLFPVHQKGGPAEDCGPVNEHRGIQRLEAMLFALDRINRDPHLLPGVRLGAHILDSCSKDTHA
LEQALDFVRASLSRGADGSRHICPDGSYATHGDAPTAITGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRY
DYFARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARARNICVATSEKVGRAMSRAAFEGVVRALL
QKPSARVAVLFTRSEDARELLAASQRLNASFTWVASDGWGALESVVAGSEGAAEGAITIELASYPISDFASYFQSLDPWN
NSRNPWFREFWEQRFRCSFRQRDCAAHSLRAVPFEQESKIMFVVNAVYAMAHALHNMHRALCPNTTRLCDAMRPVNGRRL
YKDFVLNVKFDAPFRPADTHNEVRFDRFGDGIGRYNIFTYLRAGSGRYRYQKVGYWAEGLTLDTSLIPWASPSAGPLPAS
RCSEPCLQNEVKSVQPGEVCCWLCIPCQPYEYRLDEFTCADCGLGYWPNASLTGCFELPQEYIRWGDAWAVGPVTIACLG
ALATLFVLGVFVRHNATPVVKASGRELCYILLGGVFLCYCMTFIFIAKPSTAVCTLRRLGLGTAFSVCYSALLTKTNRIA
RIFGGAREGAQRPRFISPASQVAICLALISGQLLIVVAWLVVEAPGTGKETAPERREVVTLRCNHRDASMLGSLAYNVLL
IALCTLYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIFYVTSSDYRVQTTTMCVSVSLSGSVVLGCLFAPKLHIIL
FQPQKNVVSHRAPTSRFGSAAARASSSLGQGSGSQFVPTVCNGREVVDSTTSSL
;
19 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8WG9 B 1 ? 880 ? Q14833 33 ? 912 ? 33 912 
2 2 8WG9 C 1 ? 854 ? Q14416 19 ? 872 ? 19 872 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 GLY A 43  ? ASN A 59  ? GLY B 75  ASN B 91  1 ? 17 
HELX_P HELX_P2  AA2 ASP A 80  ? ILE A 95  ? ASP B 112 ILE B 127 1 ? 16 
HELX_P HELX_P3  AA3 GLY A 126 ? ARG A 138 ? GLY B 158 ARG B 170 1 ? 13 
HELX_P HELX_P4  AA4 LEU A 139 ? LYS A 141 ? LEU B 171 LYS B 173 5 ? 3  
HELX_P HELX_P5  AA5 ALA A 151 ? ASP A 156 ? ALA B 183 ASP B 188 5 ? 6  
HELX_P HELX_P6  AA6 SER A 169 ? LEU A 184 ? SER B 201 LEU B 216 1 ? 16 
HELX_P HELX_P7  AA7 GLY A 196 ? GLY A 214 ? GLY B 228 GLY B 246 1 ? 19 
HELX_P HELX_P8  AA8 GLY A 231 ? LEU A 241 ? GLY B 263 LEU B 273 1 ? 11 
HELX_P HELX_P9  AA9 ASN A 254 ? ALA A 268 ? ASN B 286 ALA B 300 1 ? 15 
HELX_P HELX_P10 AB1 VAL A 309 ? ARG A 319 ? VAL B 341 ARG B 351 1 ? 11 
HELX_P HELX_P11 AB2 TRP A 329 ? PHE A 338 ? TRP B 361 PHE B 370 1 ? 10 
HELX_P HELX_P12 AB3 ARG A 361 ? ASP A 365 ? ARG B 393 ASP B 397 5 ? 5  
HELX_P HELX_P13 AB4 LYS A 373 ? CYS A 396 ? LYS B 405 CYS B 428 1 ? 24 
HELX_P HELX_P14 AB5 CYS A 403 ? ASP A 407 ? CYS B 435 ASP B 439 5 ? 5  
HELX_P HELX_P15 AB6 ASP A 410 ? VAL A 421 ? ASP B 442 VAL B 453 1 ? 12 
HELX_P HELX_P16 AB7 ILE A 426 ? GLY A 428 ? ILE B 458 GLY B 460 5 ? 3  
HELX_P HELX_P17 AB8 ALA A 556 ? TYR A 580 ? ALA B 588 TYR B 612 1 ? 25 
HELX_P HELX_P18 AB9 THR A 583 ? ALA A 588 ? THR B 615 ALA B 620 1 ? 6  
HELX_P HELX_P19 AC1 GLY A 590 ? MET A 611 ? GLY B 622 MET B 643 1 ? 22 
HELX_P HELX_P20 AC2 ASP A 616 ? GLY A 652 ? ASP B 648 GLY B 684 1 ? 37 
HELX_P HELX_P21 AC3 SER A 663 ? ASP A 689 ? SER B 695 ASP B 721 1 ? 27 
HELX_P HELX_P22 AC4 ASP A 704 ? ALA A 708 ? ASP B 736 ALA B 740 5 ? 5  
HELX_P HELX_P23 AC5 SER A 717 ? THR A 742 ? SER B 749 THR B 774 1 ? 26 
HELX_P HELX_P24 AC6 ARG A 743 ? VAL A 745 ? ARG B 775 VAL B 777 5 ? 3  
HELX_P HELX_P25 AC7 GLU A 751 ? ALA A 768 ? GLU B 783 ALA B 800 1 ? 18 
HELX_P HELX_P26 AC8 ALA A 768 ? THR A 776 ? ALA B 800 THR B 808 1 ? 9  
HELX_P HELX_P27 AC9 SER A 777 ? SER A 779 ? SER B 809 SER B 811 5 ? 3  
HELX_P HELX_P28 AD1 ASP A 781 ? TYR A 806 ? ASP B 813 TYR B 838 1 ? 26 
HELX_P HELX_P29 AD2 TYR A 806 ? HIS A 816 ? TYR B 838 HIS B 848 1 ? 11 
HELX_P HELX_P30 AD3 PRO A 817 ? ASN A 820 ? PRO B 849 ASN B 852 5 ? 4  
HELX_P HELX_P31 AD4 GLY B 40  ? ARG B 56  ? GLY C 58  ARG C 74  1 ? 17 
HELX_P HELX_P32 AD5 LYS B 76  ? LEU B 85  ? LYS C 94  LEU C 103 1 ? 10 
HELX_P HELX_P33 AD6 LEU B 85  ? ALA B 90  ? LEU C 103 ALA C 108 1 ? 6  
HELX_P HELX_P34 AD7 TYR B 126 ? ARG B 138 ? TYR C 144 ARG C 156 1 ? 13 
HELX_P HELX_P35 AD8 LEU B 139 ? GLN B 141 ? LEU C 157 GLN C 159 5 ? 3  
HELX_P HELX_P36 AD9 PRO B 169 ? PHE B 171 ? PRO C 187 PHE C 189 5 ? 3  
HELX_P HELX_P37 AE1 PHE B 172 ? PHE B 184 ? PHE C 190 PHE C 202 1 ? 13 
HELX_P HELX_P38 AE2 GLY B 196 ? ARG B 213 ? GLY C 214 ARG C 231 1 ? 18 
HELX_P HELX_P39 AE3 SER B 228 ? GLN B 241 ? SER C 246 GLN C 259 1 ? 14 
HELX_P HELX_P40 AE4 ARG B 253 ? LEU B 267 ? ARG C 271 LEU C 285 1 ? 15 
HELX_P HELX_P41 AE5 ASP B 277 ? GLY B 280 ? ASP C 295 GLY C 298 5 ? 4  
HELX_P HELX_P42 AE6 GLY B 291 ? GLU B 294 ? GLY C 309 GLU C 312 5 ? 4  
HELX_P HELX_P43 AE7 ILE B 306 ? SER B 315 ? ILE C 324 SER C 333 1 ? 10 
HELX_P HELX_P44 AE8 TRP B 326 ? PHE B 335 ? TRP C 344 PHE C 353 1 ? 10 
HELX_P HELX_P45 AE9 ASP B 343 ? HIS B 347 ? ASP C 361 HIS C 365 5 ? 5  
HELX_P HELX_P46 AF1 SER B 348 ? VAL B 352 ? SER C 366 VAL C 370 5 ? 5  
HELX_P HELX_P47 AF2 LYS B 359 ? CYS B 382 ? LYS C 377 CYS C 400 1 ? 24 
HELX_P HELX_P48 AF3 CYS B 389 ? ARG B 393 ? CYS C 407 ARG C 411 5 ? 5  
HELX_P HELX_P49 AF4 GLY B 397 ? LYS B 402 ? GLY C 415 LYS C 420 1 ? 6  
HELX_P HELX_P50 AF5 THR B 464 ? ILE B 467 ? THR C 482 ILE C 485 5 ? 4  
HELX_P HELX_P51 AF6 SER B 471 ? GLY B 475 ? SER C 489 GLY C 493 5 ? 5  
HELX_P HELX_P52 AF7 GLU B 498 ? TRP B 502 ? GLU C 516 TRP C 520 5 ? 5  
HELX_P HELX_P53 AF8 ALA B 550 ? HIS B 574 ? ALA C 568 HIS C 592 1 ? 25 
HELX_P HELX_P54 AF9 THR B 577 ? ALA B 582 ? THR C 595 ALA C 600 1 ? 6  
HELX_P HELX_P55 AG1 GLY B 584 ? PHE B 605 ? GLY C 602 PHE C 623 1 ? 22 
HELX_P HELX_P56 AG2 SER B 610 ? TYR B 629 ? SER C 628 TYR C 647 1 ? 20 
HELX_P HELX_P57 AG3 ALA B 631 ? ALA B 640 ? ALA C 649 ALA C 658 1 ? 10 
HELX_P HELX_P58 AG4 SER B 657 ? VAL B 681 ? SER C 675 VAL C 699 1 ? 25 
HELX_P HELX_P59 AG5 ALA B 708 ? MET B 710 ? ALA C 726 MET C 728 5 ? 3  
HELX_P HELX_P60 AG6 LEU B 711 ? LEU B 723 ? LEU C 729 LEU C 741 1 ? 13 
HELX_P HELX_P61 AG7 TYR B 727 ? CYS B 734 ? TYR C 745 CYS C 752 5 ? 8  
HELX_P HELX_P62 AG8 ASN B 737 ? LEU B 759 ? ASN C 755 LEU C 777 1 ? 23 
HELX_P HELX_P63 AG9 PRO B 760 ? THR B 765 ? PRO C 778 THR C 783 1 ? 6  
HELX_P HELX_P64 AH1 ASP B 768 ? GLN B 802 ? ASP C 786 GLN C 820 1 ? 35 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1  disulf ? ? A CYS 35  SG ? ? ? 1_555 A CYS 77  SG ? ? B CYS 67  B CYS 109 1_555 ? ? ? ? ? ? ? 2.029 ? ? 
disulf2  disulf ? ? A CYS 217 SG ? ? ? 1_555 A CYS 506 SG ? ? B CYS 249 B CYS 538 1_555 ? ? ? ? ? ? ? 2.039 ? ? 
disulf3  disulf ? ? A CYS 396 SG ? ? ? 1_555 A CYS 403 SG ? ? B CYS 428 B CYS 435 1_555 ? ? ? ? ? ? ? 2.017 ? ? 
disulf4  disulf ? ? A CYS 488 SG ? ? ? 1_555 A CYS 507 SG ? ? B CYS 520 B CYS 539 1_555 ? ? ? ? ? ? ? 2.029 ? ? 
disulf5  disulf ? ? A CYS 492 SG ? ? ? 1_555 A CYS 510 SG ? ? B CYS 524 B CYS 542 1_555 ? ? ? ? ? ? ? 2.026 ? ? 
disulf6  disulf ? ? A CYS 513 SG ? ? ? 1_555 A CYS 525 SG ? ? B CYS 545 B CYS 557 1_555 ? ? ? ? ? ? ? 1.995 ? ? 
disulf7  disulf ? ? A CYS 528 SG ? ? ? 1_555 A CYS 541 SG ? ? B CYS 560 B CYS 573 1_555 ? ? ? ? ? ? ? 2.010 ? ? 
disulf8  disulf ? ? A CYS 620 SG ? ? ? 1_555 A CYS 714 SG ? ? B CYS 652 B CYS 746 1_555 ? ? ? ? ? ? ? 2.027 ? ? 
disulf9  disulf ? ? B CYS 32  SG ? ? ? 1_555 B CYS 74  SG ? ? C CYS 50  C CYS 92  1_555 ? ? ? ? ? ? ? 2.078 ? ? 
disulf10 disulf ? ? B CYS 216 SG ? ? ? 1_555 B CYS 500 SG ? ? C CYS 234 C CYS 518 1_555 ? ? ? ? ? ? ? 2.024 ? ? 
disulf11 disulf ? ? B CYS 337 SG ? ? ? 1_555 B CYS 344 SG ? ? C CYS 355 C CYS 362 1_555 ? ? ? ? ? ? ? 2.025 ? ? 
disulf12 disulf ? ? B CYS 382 SG ? ? ? 1_555 B CYS 389 SG ? ? C CYS 400 C CYS 407 1_555 ? ? ? ? ? ? ? 2.032 ? ? 
disulf13 disulf ? ? B CYS 482 SG ? ? ? 1_555 B CYS 501 SG ? ? C CYS 500 C CYS 519 1_555 ? ? ? ? ? ? ? 2.027 ? ? 
disulf14 disulf ? ? B CYS 486 SG ? ? ? 1_555 B CYS 504 SG ? ? C CYS 504 C CYS 522 1_555 ? ? ? ? ? ? ? 2.031 ? ? 
disulf15 disulf ? ? B CYS 507 SG ? ? ? 1_555 B CYS 519 SG ? ? C CYS 525 C CYS 537 1_555 ? ? ? ? ? ? ? 2.038 ? ? 
disulf16 disulf ? ? B CYS 614 SG ? ? ? 1_555 B CYS 703 SG ? ? C CYS 632 C CYS 721 1_555 ? ? ? ? ? ? ? 2.013 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1  CYS A 35  ? CYS A 77  ? CYS B 67  ? 1_555 CYS B 109 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2  CYS A 217 ? CYS A 506 ? CYS B 249 ? 1_555 CYS B 538 ? 1_555 SG SG . . . None 'Disulfide bridge' 
3  CYS A 396 ? CYS A 403 ? CYS B 428 ? 1_555 CYS B 435 ? 1_555 SG SG . . . None 'Disulfide bridge' 
4  CYS A 488 ? CYS A 507 ? CYS B 520 ? 1_555 CYS B 539 ? 1_555 SG SG . . . None 'Disulfide bridge' 
5  CYS A 492 ? CYS A 510 ? CYS B 524 ? 1_555 CYS B 542 ? 1_555 SG SG . . . None 'Disulfide bridge' 
6  CYS A 513 ? CYS A 525 ? CYS B 545 ? 1_555 CYS B 557 ? 1_555 SG SG . . . None 'Disulfide bridge' 
7  CYS A 528 ? CYS A 541 ? CYS B 560 ? 1_555 CYS B 573 ? 1_555 SG SG . . . None 'Disulfide bridge' 
8  CYS A 620 ? CYS A 714 ? CYS B 652 ? 1_555 CYS B 746 ? 1_555 SG SG . . . None 'Disulfide bridge' 
9  CYS B 32  ? CYS B 74  ? CYS C 50  ? 1_555 CYS C 92  ? 1_555 SG SG . . . None 'Disulfide bridge' 
10 CYS B 216 ? CYS B 500 ? CYS C 234 ? 1_555 CYS C 518 ? 1_555 SG SG . . . None 'Disulfide bridge' 
11 CYS B 337 ? CYS B 344 ? CYS C 355 ? 1_555 CYS C 362 ? 1_555 SG SG . . . None 'Disulfide bridge' 
12 CYS B 382 ? CYS B 389 ? CYS C 400 ? 1_555 CYS C 407 ? 1_555 SG SG . . . None 'Disulfide bridge' 
13 CYS B 482 ? CYS B 501 ? CYS C 500 ? 1_555 CYS C 519 ? 1_555 SG SG . . . None 'Disulfide bridge' 
14 CYS B 486 ? CYS B 504 ? CYS C 504 ? 1_555 CYS C 522 ? 1_555 SG SG . . . None 'Disulfide bridge' 
15 CYS B 507 ? CYS B 519 ? CYS C 525 ? 1_555 CYS C 537 ? 1_555 SG SG . . . None 'Disulfide bridge' 
16 CYS B 614 ? CYS B 703 ? CYS C 632 ? 1_555 CYS C 721 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 6 ? 
AA2 ? 8 ? 
AA3 ? 2 ? 
AA4 ? 2 ? 
AA5 ? 2 ? 
AA6 ? 2 ? 
AA7 ? 3 ? 
AA8 ? 3 ? 
AA9 ? 2 ? 
AB1 ? 2 ? 
AB2 ? 8 ? 
AB3 ? 2 ? 
AB4 ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? parallel      
AA1 3 4 ? parallel      
AA1 4 5 ? parallel      
AA1 5 6 ? parallel      
AA2 1 2 ? parallel      
AA2 2 3 ? parallel      
AA2 3 4 ? parallel      
AA2 4 5 ? parallel      
AA2 5 6 ? anti-parallel 
AA2 6 7 ? anti-parallel 
AA2 7 8 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA7 1 2 ? parallel      
AA7 2 3 ? anti-parallel 
AA8 1 2 ? parallel      
AA8 2 3 ? parallel      
AA9 1 2 ? anti-parallel 
AB1 1 2 ? parallel      
AB2 1 2 ? parallel      
AB2 2 3 ? parallel      
AB2 3 4 ? parallel      
AB2 4 5 ? parallel      
AB2 5 6 ? anti-parallel 
AB2 6 7 ? anti-parallel 
AB2 7 8 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB4 1 2 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE A 11  ? ILE A 13  ? ILE B 43  ILE B 45  
AA1 2 LEU A 69  ? ASP A 75  ? LEU B 101 ASP B 107 
AA1 3 ILE A 17  ? PHE A 23  ? ILE B 49  PHE B 55  
AA1 4 VAL A 118 ? ILE A 122 ? VAL B 150 ILE B 154 
AA1 5 GLN A 144 ? SER A 146 ? GLN B 176 SER B 178 
AA1 6 PHE A 163 ? ARG A 165 ? PHE B 195 ARG B 197 
AA2 1 CYS A 217 ? ILE A 224 ? CYS B 249 ILE B 256 
AA2 2 TYR A 188 ? SER A 194 ? TYR B 220 SER B 226 
AA2 3 ALA A 248 ? ILE A 251 ? ALA B 280 ILE B 283 
AA2 4 PHE A 275 ? GLY A 278 ? PHE B 307 GLY B 310 
AA2 5 VAL A 300 ? PRO A 304 ? VAL B 332 PRO B 336 
AA2 6 TYR A 443 ? GLN A 449 ? TYR B 475 GLN B 481 
AA2 7 GLU A 456 ? TRP A 463 ? GLU B 488 TRP B 495 
AA2 8 LEU A 467 ? LEU A 469 ? LEU B 499 LEU B 501 
AA3 1 PHE A 423 ? SER A 424 ? PHE B 455 SER B 456 
AA3 2 PRO A 430 ? VAL A 431 ? PRO B 462 VAL B 463 
AA4 1 GLU A 496 ? THR A 500 ? GLU B 528 THR B 532 
AA4 2 TRP A 508 ? PRO A 512 ? TRP B 540 PRO B 544 
AA5 1 GLN A 517 ? ASP A 521 ? GLN B 549 ASP B 553 
AA5 2 THR A 524 ? THR A 527 ? THR B 556 THR B 559 
AA6 1 MET A 532 ? PRO A 534 ? MET B 564 PRO B 566 
AA6 2 CYS A 541 ? PRO A 543 ? CYS B 573 PRO B 575 
AA7 1 ILE A 546 ? LYS A 548 ? ILE B 578 LYS B 580 
AA7 2 ARG A 709 ? CYS A 714 ? ARG B 741 CYS B 746 
AA7 3 SER A 693 ? GLN A 700 ? SER B 725 GLN B 732 
AA8 1 LEU B 66  ? ASP B 72  ? LEU C 84  ASP C 90  
AA8 2 LEU B 14  ? PHE B 20  ? LEU C 32  PHE C 38  
AA8 3 ILE B 122 ? GLY B 123 ? ILE C 140 GLY C 141 
AA9 1 HIS B 23  ? LYS B 25  ? HIS C 41  LYS C 43  
AA9 2 CYS B 32  ? VAL B 35  ? CYS C 50  VAL C 53  
AB1 1 GLN B 144 ? SER B 146 ? GLN C 162 SER C 164 
AB1 2 PHE B 163 ? ARG B 165 ? PHE C 181 ARG C 183 
AB2 1 VAL B 217 ? VAL B 223 ? VAL C 235 VAL C 241 
AB2 2 VAL B 189 ? SER B 194 ? VAL C 207 SER C 212 
AB2 3 VAL B 247 ? LEU B 250 ? VAL C 265 LEU C 268 
AB2 4 THR B 272 ? ALA B 275 ? THR C 290 ALA C 293 
AB2 5 ALA B 296 ? LEU B 301 ? ALA C 314 LEU C 319 
AB2 6 TYR B 435 ? LEU B 441 ? TYR C 453 LEU C 459 
AB2 7 ARG B 449 ? TRP B 456 ? ARG C 467 TRP C 474 
AB2 8 LEU B 460 ? LEU B 462 ? LEU C 478 LEU C 480 
AB3 1 GLU B 490 ? LYS B 492 ? GLU C 508 LYS C 510 
AB3 2 CYS B 504 ? PRO B 506 ? CYS C 522 PRO C 524 
AB4 1 GLU B 511 ? LEU B 514 ? GLU C 529 LEU C 532 
AB4 2 THR B 518 ? ASP B 521 ? THR C 536 ASP C 539 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ILE A 13  ? N ILE B 45  O ALA A 71  ? O ALA B 103 
AA1 2 3 O GLY A 70  ? O GLY B 102 N ILE A 17  ? N ILE B 49  
AA1 3 4 N THR A 18  ? N THR B 50  O VAL A 119 ? O VAL B 151 
AA1 4 5 N VAL A 121 ? N VAL B 153 O ILE A 145 ? O ILE B 177 
AA1 5 6 N SER A 146 ? N SER B 178 O SER A 164 ? O SER B 196 
AA2 1 2 O VAL A 222 ? O VAL B 254 N THR A 191 ? N THR B 223 
AA2 2 3 N VAL A 192 ? N VAL B 224 O ILE A 250 ? O ILE B 282 
AA2 3 4 N ILE A 251 ? N ILE B 283 O MET A 277 ? O MET B 309 
AA2 4 5 N GLY A 278 ? N GLY B 310 O ILE A 302 ? O ILE B 334 
AA2 5 6 N LEU A 303 ? N LEU B 335 O ASP A 444 ? O ASP B 476 
AA2 6 7 N ILE A 445 ? N ILE B 477 O ILE A 460 ? O ILE B 492 
AA2 7 8 N SER A 462 ? N SER B 494 O HIS A 468 ? O HIS B 500 
AA3 1 2 N PHE A 423 ? N PHE B 455 O VAL A 431 ? O VAL B 463 
AA4 1 2 N LYS A 499 ? N LYS B 531 O HIS A 509 ? O HIS B 541 
AA5 1 2 N TYR A 518 ? N TYR B 550 O LYS A 526 ? O LYS B 558 
AA6 1 2 N ARG A 533 ? N ARG B 565 O ARG A 542 ? O ARG B 574 
AA7 1 2 N ILE A 547 ? N ILE B 579 O LEU A 712 ? O LEU B 744 
AA7 2 3 O VAL A 711 ? O VAL B 743 N ASP A 696 ? N ASP B 728 
AA8 1 2 O LEU B 71  ? O LEU C 89  N GLY B 18  ? N GLY C 36  
AA8 2 3 N GLY B 17  ? N GLY C 35  O ILE B 122 ? O ILE C 140 
AA9 1 2 N GLN B 24  ? N GLN C 42  O GLY B 33  ? O GLY C 51  
AB1 1 2 N SER B 146 ? N SER C 164 O ALA B 164 ? O ALA C 182 
AB2 1 2 O THR B 219 ? O THR C 237 N THR B 191 ? N THR C 209 
AB2 2 3 N VAL B 192 ? N VAL C 210 O VAL B 249 ? O VAL C 267 
AB2 3 4 N LEU B 250 ? N LEU C 268 O VAL B 274 ? O VAL C 292 
AB2 4 5 N ALA B 275 ? N ALA C 293 O ILE B 299 ? O ILE C 317 
AB2 5 6 N THR B 298 ? N THR C 316 O PHE B 438 ? O PHE C 456 
AB2 6 7 N LEU B 441 ? N LEU C 459 O ARG B 449 ? O ARG C 467 
AB2 7 8 N TYR B 455 ? N TYR C 473 O THR B 461 ? O THR C 479 
AB3 1 2 N VAL B 491 ? N VAL C 509 O ILE B 505 ? O ILE C 523 
AB4 1 2 N TYR B 512 ? N TYR C 530 O ALA B 520 ? O ALA C 538 
# 
_pdbx_entry_details.entry_id                   8WG9 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1  1 OD1 B ASN 466 ? ? OE1 B GLU 467 ? ? 1.64 
2  1 NH1 B ARG 565 ? ? CD  B PRO 577 ? ? 1.72 
3  1 NH1 B ARG 197 ? ? OD1 B ASP 470 ? ? 1.75 
4  1 NE  B ARG 338 ? ? O   B GLY 404 ? ? 1.79 
5  1 CD  B ARG 565 ? ? O   B PRO 737 ? ? 1.80 
6  1 CD  B ARG 338 ? ? O   B GLY 404 ? ? 1.82 
7  1 CB  B SER 340 ? ? NE2 B GLN 402 ? ? 1.92 
8  1 O   C ALA 811 ? ? CD2 C HIS 815 ? ? 1.94 
9  1 CZ  B ARG 338 ? ? O   B GLY 404 ? ? 1.94 
10 1 OE1 B GLU 568 ? ? NH2 B ARG 574 ? ? 2.00 
11 1 NE2 B HIS 114 ? ? NE2 B GLN 118 ? ? 2.03 
12 1 CB  B ALA 208 ? ? OH  B TYR 475 ? ? 2.09 
13 1 NH2 B ARG 338 ? ? O   B GLY 404 ? ? 2.11 
14 1 NH2 B ARG 565 ? ? O   B ALA 740 ? ? 2.19 
# 
loop_
_pdbx_validate_rmsd_bond.id 
_pdbx_validate_rmsd_bond.PDB_model_num 
_pdbx_validate_rmsd_bond.auth_atom_id_1 
_pdbx_validate_rmsd_bond.auth_asym_id_1 
_pdbx_validate_rmsd_bond.auth_comp_id_1 
_pdbx_validate_rmsd_bond.auth_seq_id_1 
_pdbx_validate_rmsd_bond.PDB_ins_code_1 
_pdbx_validate_rmsd_bond.label_alt_id_1 
_pdbx_validate_rmsd_bond.auth_atom_id_2 
_pdbx_validate_rmsd_bond.auth_asym_id_2 
_pdbx_validate_rmsd_bond.auth_comp_id_2 
_pdbx_validate_rmsd_bond.auth_seq_id_2 
_pdbx_validate_rmsd_bond.PDB_ins_code_2 
_pdbx_validate_rmsd_bond.label_alt_id_2 
_pdbx_validate_rmsd_bond.bond_value 
_pdbx_validate_rmsd_bond.bond_target_value 
_pdbx_validate_rmsd_bond.bond_deviation 
_pdbx_validate_rmsd_bond.bond_standard_deviation 
_pdbx_validate_rmsd_bond.linker_flag 
1 1 CB B TYR 667 ? ? CG B TYR 667 ? ? 1.418 1.512 -0.094 0.015 N 
2 1 CB C CYS 362 ? ? SG C CYS 362 ? ? 1.697 1.812 -0.115 0.016 N 
3 1 CB C TYR 419 ? ? CG C TYR 419 ? ? 1.402 1.512 -0.110 0.015 N 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1  1 NE B ARG 197 ? ? CZ B ARG 197 ? ? NH2 B ARG 197 ? ? 123.46 120.30 3.16  0.50 N 
2  1 NE B ARG 243 ? ? CZ B ARG 243 ? ? NH2 B ARG 243 ? ? 123.53 120.30 3.23  0.50 N 
3  1 NE B ARG 393 ? ? CZ B ARG 393 ? ? NH2 B ARG 393 ? ? 123.32 120.30 3.02  0.50 N 
4  1 NE B ARG 451 ? ? CZ B ARG 451 ? ? NH2 B ARG 451 ? ? 123.30 120.30 3.00  0.50 N 
5  1 NE B ARG 676 ? ? CZ B ARG 676 ? ? NH1 B ARG 676 ? ? 115.86 120.30 -4.44 0.50 N 
6  1 NE B ARG 686 ? ? CZ B ARG 686 ? ? NH1 B ARG 686 ? ? 116.59 120.30 -3.71 0.50 N 
7  1 C  B ASP 721 ? ? N  B PRO 722 ? ? CA  B PRO 722 ? ? 129.94 119.30 10.64 1.50 Y 
8  1 CB B TYR 838 ? ? CG B TYR 838 ? ? CD1 B TYR 838 ? ? 116.32 121.00 -4.68 0.60 N 
9  1 CB C TYR 178 ? ? CG C TYR 178 ? ? CD2 C TYR 178 ? ? 117.39 121.00 -3.61 0.60 N 
10 1 CB C TYR 180 ? ? CG C TYR 180 ? ? CD2 C TYR 180 ? ? 117.38 121.00 -3.62 0.60 N 
11 1 NE C ARG 271 ? ? CZ C ARG 271 ? ? NH2 C ARG 271 ? ? 124.91 120.30 4.61  0.50 N 
12 1 C  C ASP 335 ? ? N  C PRO 336 ? ? CA  C PRO 336 ? ? 130.01 119.30 10.71 1.50 Y 
13 1 NE C ARG 411 ? ? CZ C ARG 411 ? ? NH1 C ARG 411 ? ? 116.28 120.30 -4.02 0.50 N 
14 1 CB C TYR 419 ? ? CG C TYR 419 ? ? CD1 C TYR 419 ? ? 117.29 121.00 -3.71 0.60 N 
15 1 CB C TYR 466 ? ? CG C TYR 466 ? ? CD2 C TYR 466 ? ? 116.85 121.00 -4.15 0.60 N 
16 1 NE C ARG 467 ? ? CZ C ARG 467 ? ? NH2 C ARG 467 ? ? 123.43 120.30 3.13  0.50 N 
17 1 CB C TYR 617 ? ? CG C TYR 617 ? ? CD2 C TYR 617 ? ? 116.97 121.00 -4.03 0.60 N 
18 1 CB C TYR 647 ? ? CG C TYR 647 ? ? CD2 C TYR 647 ? ? 117.26 121.00 -3.74 0.60 N 
19 1 CB C TYR 745 ? ? CG C TYR 745 ? ? CD2 C TYR 745 ? ? 116.55 121.00 -4.45 0.60 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 PRO B 66  ? ? -73.85  32.09   
2  1 CYS B 67  ? ? -159.93 76.61   
3  1 CYS B 109 ? ? 49.65   -121.90 
4  1 SER B 110 ? ? -150.55 -34.65  
5  1 ALA B 156 ? ? 50.31   -137.80 
6  1 SER B 157 ? ? 59.83   -156.33 
7  1 SER B 159 ? ? -60.37  -71.86  
8  1 TYR B 179 ? ? -69.58  1.97    
9  1 ALA B 180 ? ? -140.04 -93.19  
10 1 GLU B 259 ? ? -119.57 73.51   
11 1 SER B 311 ? ? -66.47  -174.92 
12 1 HIS B 323 ? ? 67.12   -9.82   
13 1 PRO B 336 ? ? -39.53  141.27  
14 1 ASP B 426 ? ? -109.49 -67.40  
15 1 CYS B 520 ? ? 62.23   -149.47 
16 1 LYS B 534 ? ? 47.22   -129.98 
17 1 ARG B 570 ? ? 52.33   19.15   
18 1 PRO B 575 ? ? -38.69  130.74  
19 1 ASP B 721 ? ? -150.22 88.55   
20 1 ARG B 733 ? ? -68.44  77.99   
21 1 TYR B 838 ? ? -124.74 -51.92  
22 1 SER C 143 ? ? -127.36 -77.78  
23 1 SER C 169 ? ? -38.81  132.83  
24 1 ASN C 203 ? ? 63.42   -2.80   
25 1 THR C 205 ? ? -149.92 -69.48  
26 1 ALA C 299 ? ? 52.99   -108.14 
27 1 SER C 307 ? ? -156.63 38.33   
28 1 PHE C 428 ? ? -161.02 -168.18 
29 1 GLU C 440 ? ? 38.87   64.23   
30 1 ALA C 475 ? ? -142.37 -62.38  
31 1 ALA C 488 ? ? -141.78 -21.98  
32 1 CYS C 500 ? ? -130.63 -67.72  
33 1 PRO C 503 ? ? -68.98  65.12   
34 1 GLN C 506 ? ? -148.41 -143.20 
35 1 PRO C 527 ? ? -78.24  44.45   
36 1 ASP C 533 ? ? 61.87   -177.24 
37 1 TRP C 545 ? ? 37.00   46.36   
38 1 THR C 709 ? ? 44.31   -132.87 
39 1 ARG C 713 ? ? 72.23   -52.49  
40 1 ARG C 714 ? ? 61.58   -46.72  
41 1 THR C 718 ? ? 66.14   86.98   
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1 1 TYR B 179 ? ? 0.071 'SIDE CHAIN' 
2 1 TYR B 230 ? ? 0.075 'SIDE CHAIN' 
3 1 PHE B 307 ? ? 0.091 'SIDE CHAIN' 
4 1 TYR B 475 ? ? 0.085 'SIDE CHAIN' 
5 1 TYR B 489 ? ? 0.097 'SIDE CHAIN' 
6 1 TYR B 550 ? ? 0.071 'SIDE CHAIN' 
7 1 PHE C 189 ? ? 0.084 'SIDE CHAIN' 
8 1 TYR C 458 ? ? 0.070 'SIDE CHAIN' 
9 1 TYR C 530 ? ? 0.065 'SIDE CHAIN' 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8WG9 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8WG9 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  4.46 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               112924 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'mGlu2-mGlu4 heterodimer bound L-AP4' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2' 
# 
_em_imaging.entry_id                        8WG9 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             600 
_em_imaging.nominal_defocus_max             3000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8WG9 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8WG9 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 B LYS 33  ? A LYS 1   
2   1 Y 1 B PRO 34  ? A PRO 2   
3   1 Y 1 B LYS 35  ? A LYS 3   
4   1 Y 1 B GLY 36  ? A GLY 4   
5   1 Y 1 B HIS 37  ? A HIS 5   
6   1 Y 1 B PRO 38  ? A PRO 6   
7   1 Y 1 B HIS 39  ? A HIS 7   
8   1 Y 1 B MET 40  ? A MET 8   
9   1 Y 1 B GLU 128 ? A GLU 96  
10  1 Y 1 B LYS 129 ? A LYS 97  
11  1 Y 1 B ASP 130 ? A ASP 98  
12  1 Y 1 B GLY 131 ? A GLY 99  
13  1 Y 1 B THR 132 ? A THR 100 
14  1 Y 1 B GLU 133 ? A GLU 101 
15  1 Y 1 B VAL 134 ? A VAL 102 
16  1 Y 1 B ARG 135 ? A ARG 103 
17  1 Y 1 B CYS 136 ? A CYS 104 
18  1 Y 1 B GLY 137 ? A GLY 105 
19  1 Y 1 B SER 138 ? A SER 106 
20  1 Y 1 B GLY 139 ? A GLY 107 
21  1 Y 1 B GLY 140 ? A GLY 108 
22  1 Y 1 B PRO 141 ? A PRO 109 
23  1 Y 1 B PRO 142 ? A PRO 110 
24  1 Y 1 B ILE 143 ? A ILE 111 
25  1 Y 1 B ILE 144 ? A ILE 112 
26  1 Y 1 B THR 145 ? A THR 113 
27  1 Y 1 B LYS 146 ? A LYS 114 
28  1 Y 1 B PRO 147 ? A PRO 115 
29  1 Y 1 B SER 375 ? A SER 343 
30  1 Y 1 B ARG 376 ? A ARG 344 
31  1 Y 1 B HIS 377 ? A HIS 345 
32  1 Y 1 B ALA 378 ? A ALA 346 
33  1 Y 1 B LEU 379 ? A LEU 347 
34  1 Y 1 B LYS 380 ? A LYS 348 
35  1 Y 1 B LYS 381 ? A LYS 349 
36  1 Y 1 B GLY 382 ? A GLY 350 
37  1 Y 1 B SER 383 ? A SER 351 
38  1 Y 1 B HIS 384 ? A HIS 352 
39  1 Y 1 B ASN 484 ? A ASN 452 
40  1 Y 1 B ASP 485 ? A ASP 453 
41  1 Y 1 B SER 486 ? A SER 454 
42  1 Y 1 B GLU 504 ? A GLU 472 
43  1 Y 1 B ARG 505 ? A ARG 473 
44  1 Y 1 B MET 506 ? A MET 474 
45  1 Y 1 B HIS 507 ? A HIS 475 
46  1 Y 1 B TRP 508 ? A TRP 476 
47  1 Y 1 B PRO 509 ? A PRO 477 
48  1 Y 1 B GLY 510 ? A GLY 478 
49  1 Y 1 B SER 511 ? A SER 479 
50  1 Y 1 B GLY 512 ? A GLY 480 
51  1 Y 1 B ARG 856 ? A ARG 824 
52  1 Y 1 B LYS 857 ? A LYS 825 
53  1 Y 1 B ARG 858 ? A ARG 826 
54  1 Y 1 B SER 859 ? A SER 827 
55  1 Y 1 B LEU 860 ? A LEU 828 
56  1 Y 1 B LYS 861 ? A LYS 829 
57  1 Y 1 B ALA 862 ? A ALA 830 
58  1 Y 1 B VAL 863 ? A VAL 831 
59  1 Y 1 B VAL 864 ? A VAL 832 
60  1 Y 1 B THR 865 ? A THR 833 
61  1 Y 1 B ALA 866 ? A ALA 834 
62  1 Y 1 B ALA 867 ? A ALA 835 
63  1 Y 1 B THR 868 ? A THR 836 
64  1 Y 1 B MET 869 ? A MET 837 
65  1 Y 1 B SER 870 ? A SER 838 
66  1 Y 1 B ASN 871 ? A ASN 839 
67  1 Y 1 B LYS 872 ? A LYS 840 
68  1 Y 1 B PHE 873 ? A PHE 841 
69  1 Y 1 B THR 874 ? A THR 842 
70  1 Y 1 B GLN 875 ? A GLN 843 
71  1 Y 1 B LYS 876 ? A LYS 844 
72  1 Y 1 B GLY 877 ? A GLY 845 
73  1 Y 1 B ASN 878 ? A ASN 846 
74  1 Y 1 B PHE 879 ? A PHE 847 
75  1 Y 1 B ARG 880 ? A ARG 848 
76  1 Y 1 B PRO 881 ? A PRO 849 
77  1 Y 1 B ASN 882 ? A ASN 850 
78  1 Y 1 B GLY 883 ? A GLY 851 
79  1 Y 1 B GLU 884 ? A GLU 852 
80  1 Y 1 B ALA 885 ? A ALA 853 
81  1 Y 1 B LYS 886 ? A LYS 854 
82  1 Y 1 B SER 887 ? A SER 855 
83  1 Y 1 B GLU 888 ? A GLU 856 
84  1 Y 1 B LEU 889 ? A LEU 857 
85  1 Y 1 B CYS 890 ? A CYS 858 
86  1 Y 1 B GLU 891 ? A GLU 859 
87  1 Y 1 B ASN 892 ? A ASN 860 
88  1 Y 1 B LEU 893 ? A LEU 861 
89  1 Y 1 B GLU 894 ? A GLU 862 
90  1 Y 1 B ALA 895 ? A ALA 863 
91  1 Y 1 B PRO 896 ? A PRO 864 
92  1 Y 1 B ALA 897 ? A ALA 865 
93  1 Y 1 B LEU 898 ? A LEU 866 
94  1 Y 1 B ALA 899 ? A ALA 867 
95  1 Y 1 B THR 900 ? A THR 868 
96  1 Y 1 B LYS 901 ? A LYS 869 
97  1 Y 1 B GLN 902 ? A GLN 870 
98  1 Y 1 B THR 903 ? A THR 871 
99  1 Y 1 B TYR 904 ? A TYR 872 
100 1 Y 1 B VAL 905 ? A VAL 873 
101 1 Y 1 B THR 906 ? A THR 874 
102 1 Y 1 B TYR 907 ? A TYR 875 
103 1 Y 1 B THR 908 ? A THR 876 
104 1 Y 1 B ASN 909 ? A ASN 877 
105 1 Y 1 B HIS 910 ? A HIS 878 
106 1 Y 1 B ALA 911 ? A ALA 879 
107 1 Y 1 B ILE 912 ? A ILE 880 
108 1 Y 1 C GLU 19  ? B GLU 1   
109 1 Y 1 C GLY 20  ? B GLY 2   
110 1 Y 1 C PRO 21  ? B PRO 3   
111 1 Y 1 C ALA 22  ? B ALA 4   
112 1 Y 1 C LEU 110 ? B LEU 92  
113 1 Y 1 C SER 111 ? B SER 93  
114 1 Y 1 C ARG 112 ? B ARG 94  
115 1 Y 1 C GLY 113 ? B GLY 95  
116 1 Y 1 C ALA 114 ? B ALA 96  
117 1 Y 1 C ASP 115 ? B ASP 97  
118 1 Y 1 C GLY 116 ? B GLY 98  
119 1 Y 1 C SER 117 ? B SER 99  
120 1 Y 1 C ARG 118 ? B ARG 100 
121 1 Y 1 C HIS 119 ? B HIS 101 
122 1 Y 1 C ILE 120 ? B ILE 102 
123 1 Y 1 C CYS 121 ? B CYS 103 
124 1 Y 1 C PRO 122 ? B PRO 104 
125 1 Y 1 C ASP 123 ? B ASP 105 
126 1 Y 1 C GLY 124 ? B GLY 106 
127 1 Y 1 C SER 125 ? B SER 107 
128 1 Y 1 C TYR 126 ? B TYR 108 
129 1 Y 1 C ALA 127 ? B ALA 109 
130 1 Y 1 C THR 128 ? B THR 110 
131 1 Y 1 C HIS 129 ? B HIS 111 
132 1 Y 1 C GLY 130 ? B GLY 112 
133 1 Y 1 C ASP 131 ? B ASP 113 
134 1 Y 1 C ALA 132 ? B ALA 114 
135 1 Y 1 C PRO 133 ? B PRO 115 
136 1 Y 1 C THR 134 ? B THR 116 
137 1 Y 1 C ALA 135 ? B ALA 117 
138 1 Y 1 C ILE 136 ? B ILE 118 
139 1 Y 1 C THR 137 ? B THR 119 
140 1 Y 1 C GLY 138 ? B GLY 120 
141 1 Y 1 C SER 549 ? B SER 531 
142 1 Y 1 C LEU 550 ? B LEU 532 
143 1 Y 1 C THR 551 ? B THR 533 
144 1 Y 1 C GLY 552 ? B GLY 534 
145 1 Y 1 C CYS 553 ? B CYS 535 
146 1 Y 1 C PHE 554 ? B PHE 536 
147 1 Y 1 C GLU 555 ? B GLU 537 
148 1 Y 1 C LEU 556 ? B LEU 538 
149 1 Y 1 C PRO 557 ? B PRO 539 
150 1 Y 1 C GLN 558 ? B GLN 540 
151 1 Y 1 C GLU 559 ? B GLU 541 
152 1 Y 1 C TYR 560 ? B TYR 542 
153 1 Y 1 C ILE 561 ? B ILE 543 
154 1 Y 1 C ARG 562 ? B ARG 544 
155 1 Y 1 C TRP 563 ? B TRP 545 
156 1 Y 1 C GLY 564 ? B GLY 546 
157 1 Y 1 C ARG 659 ? B ARG 641 
158 1 Y 1 C ILE 660 ? B ILE 642 
159 1 Y 1 C PHE 661 ? B PHE 643 
160 1 Y 1 C GLY 662 ? B GLY 644 
161 1 Y 1 C GLY 663 ? B GLY 645 
162 1 Y 1 C ALA 664 ? B ALA 646 
163 1 Y 1 C ARG 665 ? B ARG 647 
164 1 Y 1 C GLU 666 ? B GLU 648 
165 1 Y 1 C GLY 667 ? B GLY 649 
166 1 Y 1 C ALA 668 ? B ALA 650 
167 1 Y 1 C GLN 669 ? B GLN 651 
168 1 Y 1 C ARG 670 ? B ARG 652 
169 1 Y 1 C PRO 671 ? B PRO 653 
170 1 Y 1 C ARG 672 ? B ARG 654 
171 1 Y 1 C PHE 673 ? B PHE 655 
172 1 Y 1 C PRO 821 ? B PRO 803 
173 1 Y 1 C GLN 822 ? B GLN 804 
174 1 Y 1 C LYS 823 ? B LYS 805 
175 1 Y 1 C ASN 824 ? B ASN 806 
176 1 Y 1 C VAL 825 ? B VAL 807 
177 1 Y 1 C VAL 826 ? B VAL 808 
178 1 Y 1 C SER 827 ? B SER 809 
179 1 Y 1 C HIS 828 ? B HIS 810 
180 1 Y 1 C ARG 829 ? B ARG 811 
181 1 Y 1 C ALA 830 ? B ALA 812 
182 1 Y 1 C PRO 831 ? B PRO 813 
183 1 Y 1 C THR 832 ? B THR 814 
184 1 Y 1 C SER 833 ? B SER 815 
185 1 Y 1 C ARG 834 ? B ARG 816 
186 1 Y 1 C PHE 835 ? B PHE 817 
187 1 Y 1 C GLY 836 ? B GLY 818 
188 1 Y 1 C SER 837 ? B SER 819 
189 1 Y 1 C ALA 838 ? B ALA 820 
190 1 Y 1 C ALA 839 ? B ALA 821 
191 1 Y 1 C ALA 840 ? B ALA 822 
192 1 Y 1 C ARG 841 ? B ARG 823 
193 1 Y 1 C ALA 842 ? B ALA 824 
194 1 Y 1 C SER 843 ? B SER 825 
195 1 Y 1 C SER 844 ? B SER 826 
196 1 Y 1 C SER 845 ? B SER 827 
197 1 Y 1 C LEU 846 ? B LEU 828 
198 1 Y 1 C GLY 847 ? B GLY 829 
199 1 Y 1 C GLN 848 ? B GLN 830 
200 1 Y 1 C GLY 849 ? B GLY 831 
201 1 Y 1 C SER 850 ? B SER 832 
202 1 Y 1 C GLY 851 ? B GLY 833 
203 1 Y 1 C SER 852 ? B SER 834 
204 1 Y 1 C GLN 853 ? B GLN 835 
205 1 Y 1 C PHE 854 ? B PHE 836 
206 1 Y 1 C VAL 855 ? B VAL 837 
207 1 Y 1 C PRO 856 ? B PRO 838 
208 1 Y 1 C THR 857 ? B THR 839 
209 1 Y 1 C VAL 858 ? B VAL 840 
210 1 Y 1 C CYS 859 ? B CYS 841 
211 1 Y 1 C ASN 860 ? B ASN 842 
212 1 Y 1 C GLY 861 ? B GLY 843 
213 1 Y 1 C ARG 862 ? B ARG 844 
214 1 Y 1 C GLU 863 ? B GLU 845 
215 1 Y 1 C VAL 864 ? B VAL 846 
216 1 Y 1 C VAL 865 ? B VAL 847 
217 1 Y 1 C ASP 866 ? B ASP 848 
218 1 Y 1 C SER 867 ? B SER 849 
219 1 Y 1 C THR 868 ? B THR 850 
220 1 Y 1 C THR 869 ? B THR 851 
221 1 Y 1 C SER 870 ? B SER 852 
222 1 Y 1 C SER 871 ? B SER 853 
223 1 Y 1 C LEU 872 ? B LEU 854 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
E7P O1   O N N 88  
E7P O2   O N N 89  
E7P C1   C N N 90  
E7P C    C N N 91  
E7P CA   C N S 92  
E7P C2   C N N 93  
E7P O    O N N 94  
E7P OXT  O N N 95  
E7P N    N N N 96  
E7P P    P N N 97  
E7P O3   O N N 98  
E7P H1   H N N 99  
E7P H4   H N N 100 
E7P H3   H N N 101 
E7P HA   H N N 102 
E7P H5   H N N 103 
E7P H6   H N N 104 
E7P HXT  H N N 105 
E7P H    H N N 106 
E7P H2   H N N 107 
E7P H11  H N N 108 
GLN N    N N N 109 
GLN CA   C N S 110 
GLN C    C N N 111 
GLN O    O N N 112 
GLN CB   C N N 113 
GLN CG   C N N 114 
GLN CD   C N N 115 
GLN OE1  O N N 116 
GLN NE2  N N N 117 
GLN OXT  O N N 118 
GLN H    H N N 119 
GLN H2   H N N 120 
GLN HA   H N N 121 
GLN HB2  H N N 122 
GLN HB3  H N N 123 
GLN HG2  H N N 124 
GLN HG3  H N N 125 
GLN HE21 H N N 126 
GLN HE22 H N N 127 
GLN HXT  H N N 128 
GLU N    N N N 129 
GLU CA   C N S 130 
GLU C    C N N 131 
GLU O    O N N 132 
GLU CB   C N N 133 
GLU CG   C N N 134 
GLU CD   C N N 135 
GLU OE1  O N N 136 
GLU OE2  O N N 137 
GLU OXT  O N N 138 
GLU H    H N N 139 
GLU H2   H N N 140 
GLU HA   H N N 141 
GLU HB2  H N N 142 
GLU HB3  H N N 143 
GLU HG2  H N N 144 
GLU HG3  H N N 145 
GLU HE2  H N N 146 
GLU HXT  H N N 147 
GLY N    N N N 148 
GLY CA   C N N 149 
GLY C    C N N 150 
GLY O    O N N 151 
GLY OXT  O N N 152 
GLY H    H N N 153 
GLY H2   H N N 154 
GLY HA2  H N N 155 
GLY HA3  H N N 156 
GLY HXT  H N N 157 
HIS N    N N N 158 
HIS CA   C N S 159 
HIS C    C N N 160 
HIS O    O N N 161 
HIS CB   C N N 162 
HIS CG   C Y N 163 
HIS ND1  N Y N 164 
HIS CD2  C Y N 165 
HIS CE1  C Y N 166 
HIS NE2  N Y N 167 
HIS OXT  O N N 168 
HIS H    H N N 169 
HIS H2   H N N 170 
HIS HA   H N N 171 
HIS HB2  H N N 172 
HIS HB3  H N N 173 
HIS HD1  H N N 174 
HIS HD2  H N N 175 
HIS HE1  H N N 176 
HIS HE2  H N N 177 
HIS HXT  H N N 178 
ILE N    N N N 179 
ILE CA   C N S 180 
ILE C    C N N 181 
ILE O    O N N 182 
ILE CB   C N S 183 
ILE CG1  C N N 184 
ILE CG2  C N N 185 
ILE CD1  C N N 186 
ILE OXT  O N N 187 
ILE H    H N N 188 
ILE H2   H N N 189 
ILE HA   H N N 190 
ILE HB   H N N 191 
ILE HG12 H N N 192 
ILE HG13 H N N 193 
ILE HG21 H N N 194 
ILE HG22 H N N 195 
ILE HG23 H N N 196 
ILE HD11 H N N 197 
ILE HD12 H N N 198 
ILE HD13 H N N 199 
ILE HXT  H N N 200 
LEU N    N N N 201 
LEU CA   C N S 202 
LEU C    C N N 203 
LEU O    O N N 204 
LEU CB   C N N 205 
LEU CG   C N N 206 
LEU CD1  C N N 207 
LEU CD2  C N N 208 
LEU OXT  O N N 209 
LEU H    H N N 210 
LEU H2   H N N 211 
LEU HA   H N N 212 
LEU HB2  H N N 213 
LEU HB3  H N N 214 
LEU HG   H N N 215 
LEU HD11 H N N 216 
LEU HD12 H N N 217 
LEU HD13 H N N 218 
LEU HD21 H N N 219 
LEU HD22 H N N 220 
LEU HD23 H N N 221 
LEU HXT  H N N 222 
LYS N    N N N 223 
LYS CA   C N S 224 
LYS C    C N N 225 
LYS O    O N N 226 
LYS CB   C N N 227 
LYS CG   C N N 228 
LYS CD   C N N 229 
LYS CE   C N N 230 
LYS NZ   N N N 231 
LYS OXT  O N N 232 
LYS H    H N N 233 
LYS H2   H N N 234 
LYS HA   H N N 235 
LYS HB2  H N N 236 
LYS HB3  H N N 237 
LYS HG2  H N N 238 
LYS HG3  H N N 239 
LYS HD2  H N N 240 
LYS HD3  H N N 241 
LYS HE2  H N N 242 
LYS HE3  H N N 243 
LYS HZ1  H N N 244 
LYS HZ2  H N N 245 
LYS HZ3  H N N 246 
LYS HXT  H N N 247 
MET N    N N N 248 
MET CA   C N S 249 
MET C    C N N 250 
MET O    O N N 251 
MET CB   C N N 252 
MET CG   C N N 253 
MET SD   S N N 254 
MET CE   C N N 255 
MET OXT  O N N 256 
MET H    H N N 257 
MET H2   H N N 258 
MET HA   H N N 259 
MET HB2  H N N 260 
MET HB3  H N N 261 
MET HG2  H N N 262 
MET HG3  H N N 263 
MET HE1  H N N 264 
MET HE2  H N N 265 
MET HE3  H N N 266 
MET HXT  H N N 267 
PHE N    N N N 268 
PHE CA   C N S 269 
PHE C    C N N 270 
PHE O    O N N 271 
PHE CB   C N N 272 
PHE CG   C Y N 273 
PHE CD1  C Y N 274 
PHE CD2  C Y N 275 
PHE CE1  C Y N 276 
PHE CE2  C Y N 277 
PHE CZ   C Y N 278 
PHE OXT  O N N 279 
PHE H    H N N 280 
PHE H2   H N N 281 
PHE HA   H N N 282 
PHE HB2  H N N 283 
PHE HB3  H N N 284 
PHE HD1  H N N 285 
PHE HD2  H N N 286 
PHE HE1  H N N 287 
PHE HE2  H N N 288 
PHE HZ   H N N 289 
PHE HXT  H N N 290 
PRO N    N N N 291 
PRO CA   C N S 292 
PRO C    C N N 293 
PRO O    O N N 294 
PRO CB   C N N 295 
PRO CG   C N N 296 
PRO CD   C N N 297 
PRO OXT  O N N 298 
PRO H    H N N 299 
PRO HA   H N N 300 
PRO HB2  H N N 301 
PRO HB3  H N N 302 
PRO HG2  H N N 303 
PRO HG3  H N N 304 
PRO HD2  H N N 305 
PRO HD3  H N N 306 
PRO HXT  H N N 307 
SER N    N N N 308 
SER CA   C N S 309 
SER C    C N N 310 
SER O    O N N 311 
SER CB   C N N 312 
SER OG   O N N 313 
SER OXT  O N N 314 
SER H    H N N 315 
SER H2   H N N 316 
SER HA   H N N 317 
SER HB2  H N N 318 
SER HB3  H N N 319 
SER HG   H N N 320 
SER HXT  H N N 321 
THR N    N N N 322 
THR CA   C N S 323 
THR C    C N N 324 
THR O    O N N 325 
THR CB   C N R 326 
THR OG1  O N N 327 
THR CG2  C N N 328 
THR OXT  O N N 329 
THR H    H N N 330 
THR H2   H N N 331 
THR HA   H N N 332 
THR HB   H N N 333 
THR HG1  H N N 334 
THR HG21 H N N 335 
THR HG22 H N N 336 
THR HG23 H N N 337 
THR HXT  H N N 338 
TRP N    N N N 339 
TRP CA   C N S 340 
TRP C    C N N 341 
TRP O    O N N 342 
TRP CB   C N N 343 
TRP CG   C Y N 344 
TRP CD1  C Y N 345 
TRP CD2  C Y N 346 
TRP NE1  N Y N 347 
TRP CE2  C Y N 348 
TRP CE3  C Y N 349 
TRP CZ2  C Y N 350 
TRP CZ3  C Y N 351 
TRP CH2  C Y N 352 
TRP OXT  O N N 353 
TRP H    H N N 354 
TRP H2   H N N 355 
TRP HA   H N N 356 
TRP HB2  H N N 357 
TRP HB3  H N N 358 
TRP HD1  H N N 359 
TRP HE1  H N N 360 
TRP HE3  H N N 361 
TRP HZ2  H N N 362 
TRP HZ3  H N N 363 
TRP HH2  H N N 364 
TRP HXT  H N N 365 
TYR N    N N N 366 
TYR CA   C N S 367 
TYR C    C N N 368 
TYR O    O N N 369 
TYR CB   C N N 370 
TYR CG   C Y N 371 
TYR CD1  C Y N 372 
TYR CD2  C Y N 373 
TYR CE1  C Y N 374 
TYR CE2  C Y N 375 
TYR CZ   C Y N 376 
TYR OH   O N N 377 
TYR OXT  O N N 378 
TYR H    H N N 379 
TYR H2   H N N 380 
TYR HA   H N N 381 
TYR HB2  H N N 382 
TYR HB3  H N N 383 
TYR HD1  H N N 384 
TYR HD2  H N N 385 
TYR HE1  H N N 386 
TYR HE2  H N N 387 
TYR HH   H N N 388 
TYR HXT  H N N 389 
VAL N    N N N 390 
VAL CA   C N S 391 
VAL C    C N N 392 
VAL O    O N N 393 
VAL CB   C N N 394 
VAL CG1  C N N 395 
VAL CG2  C N N 396 
VAL OXT  O N N 397 
VAL H    H N N 398 
VAL H2   H N N 399 
VAL HA   H N N 400 
VAL HB   H N N 401 
VAL HG11 H N N 402 
VAL HG12 H N N 403 
VAL HG13 H N N 404 
VAL HG21 H N N 405 
VAL HG22 H N N 406 
VAL HG23 H N N 407 
VAL HXT  H N N 408 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
E7P O2  P    doub N N 83  
E7P O   C    doub N N 84  
E7P CA  C    sing N N 85  
E7P CA  N    sing N N 86  
E7P CA  C2   sing N N 87  
E7P C   OXT  sing N N 88  
E7P P   O3   sing N N 89  
E7P P   C1   sing N N 90  
E7P P   O1   sing N N 91  
E7P C1  C2   sing N N 92  
E7P O1  H1   sing N N 93  
E7P C1  H4   sing N N 94  
E7P C1  H3   sing N N 95  
E7P CA  HA   sing N N 96  
E7P C2  H5   sing N N 97  
E7P C2  H6   sing N N 98  
E7P OXT HXT  sing N N 99  
E7P N   H    sing N N 100 
E7P N   H2   sing N N 101 
E7P O3  H11  sing N N 102 
GLN N   CA   sing N N 103 
GLN N   H    sing N N 104 
GLN N   H2   sing N N 105 
GLN CA  C    sing N N 106 
GLN CA  CB   sing N N 107 
GLN CA  HA   sing N N 108 
GLN C   O    doub N N 109 
GLN C   OXT  sing N N 110 
GLN CB  CG   sing N N 111 
GLN CB  HB2  sing N N 112 
GLN CB  HB3  sing N N 113 
GLN CG  CD   sing N N 114 
GLN CG  HG2  sing N N 115 
GLN CG  HG3  sing N N 116 
GLN CD  OE1  doub N N 117 
GLN CD  NE2  sing N N 118 
GLN NE2 HE21 sing N N 119 
GLN NE2 HE22 sing N N 120 
GLN OXT HXT  sing N N 121 
GLU N   CA   sing N N 122 
GLU N   H    sing N N 123 
GLU N   H2   sing N N 124 
GLU CA  C    sing N N 125 
GLU CA  CB   sing N N 126 
GLU CA  HA   sing N N 127 
GLU C   O    doub N N 128 
GLU C   OXT  sing N N 129 
GLU CB  CG   sing N N 130 
GLU CB  HB2  sing N N 131 
GLU CB  HB3  sing N N 132 
GLU CG  CD   sing N N 133 
GLU CG  HG2  sing N N 134 
GLU CG  HG3  sing N N 135 
GLU CD  OE1  doub N N 136 
GLU CD  OE2  sing N N 137 
GLU OE2 HE2  sing N N 138 
GLU OXT HXT  sing N N 139 
GLY N   CA   sing N N 140 
GLY N   H    sing N N 141 
GLY N   H2   sing N N 142 
GLY CA  C    sing N N 143 
GLY CA  HA2  sing N N 144 
GLY CA  HA3  sing N N 145 
GLY C   O    doub N N 146 
GLY C   OXT  sing N N 147 
GLY OXT HXT  sing N N 148 
HIS N   CA   sing N N 149 
HIS N   H    sing N N 150 
HIS N   H2   sing N N 151 
HIS CA  C    sing N N 152 
HIS CA  CB   sing N N 153 
HIS CA  HA   sing N N 154 
HIS C   O    doub N N 155 
HIS C   OXT  sing N N 156 
HIS CB  CG   sing N N 157 
HIS CB  HB2  sing N N 158 
HIS CB  HB3  sing N N 159 
HIS CG  ND1  sing Y N 160 
HIS CG  CD2  doub Y N 161 
HIS ND1 CE1  doub Y N 162 
HIS ND1 HD1  sing N N 163 
HIS CD2 NE2  sing Y N 164 
HIS CD2 HD2  sing N N 165 
HIS CE1 NE2  sing Y N 166 
HIS CE1 HE1  sing N N 167 
HIS NE2 HE2  sing N N 168 
HIS OXT HXT  sing N N 169 
ILE N   CA   sing N N 170 
ILE N   H    sing N N 171 
ILE N   H2   sing N N 172 
ILE CA  C    sing N N 173 
ILE CA  CB   sing N N 174 
ILE CA  HA   sing N N 175 
ILE C   O    doub N N 176 
ILE C   OXT  sing N N 177 
ILE CB  CG1  sing N N 178 
ILE CB  CG2  sing N N 179 
ILE CB  HB   sing N N 180 
ILE CG1 CD1  sing N N 181 
ILE CG1 HG12 sing N N 182 
ILE CG1 HG13 sing N N 183 
ILE CG2 HG21 sing N N 184 
ILE CG2 HG22 sing N N 185 
ILE CG2 HG23 sing N N 186 
ILE CD1 HD11 sing N N 187 
ILE CD1 HD12 sing N N 188 
ILE CD1 HD13 sing N N 189 
ILE OXT HXT  sing N N 190 
LEU N   CA   sing N N 191 
LEU N   H    sing N N 192 
LEU N   H2   sing N N 193 
LEU CA  C    sing N N 194 
LEU CA  CB   sing N N 195 
LEU CA  HA   sing N N 196 
LEU C   O    doub N N 197 
LEU C   OXT  sing N N 198 
LEU CB  CG   sing N N 199 
LEU CB  HB2  sing N N 200 
LEU CB  HB3  sing N N 201 
LEU CG  CD1  sing N N 202 
LEU CG  CD2  sing N N 203 
LEU CG  HG   sing N N 204 
LEU CD1 HD11 sing N N 205 
LEU CD1 HD12 sing N N 206 
LEU CD1 HD13 sing N N 207 
LEU CD2 HD21 sing N N 208 
LEU CD2 HD22 sing N N 209 
LEU CD2 HD23 sing N N 210 
LEU OXT HXT  sing N N 211 
LYS N   CA   sing N N 212 
LYS N   H    sing N N 213 
LYS N   H2   sing N N 214 
LYS CA  C    sing N N 215 
LYS CA  CB   sing N N 216 
LYS CA  HA   sing N N 217 
LYS C   O    doub N N 218 
LYS C   OXT  sing N N 219 
LYS CB  CG   sing N N 220 
LYS CB  HB2  sing N N 221 
LYS CB  HB3  sing N N 222 
LYS CG  CD   sing N N 223 
LYS CG  HG2  sing N N 224 
LYS CG  HG3  sing N N 225 
LYS CD  CE   sing N N 226 
LYS CD  HD2  sing N N 227 
LYS CD  HD3  sing N N 228 
LYS CE  NZ   sing N N 229 
LYS CE  HE2  sing N N 230 
LYS CE  HE3  sing N N 231 
LYS NZ  HZ1  sing N N 232 
LYS NZ  HZ2  sing N N 233 
LYS NZ  HZ3  sing N N 234 
LYS OXT HXT  sing N N 235 
MET N   CA   sing N N 236 
MET N   H    sing N N 237 
MET N   H2   sing N N 238 
MET CA  C    sing N N 239 
MET CA  CB   sing N N 240 
MET CA  HA   sing N N 241 
MET C   O    doub N N 242 
MET C   OXT  sing N N 243 
MET CB  CG   sing N N 244 
MET CB  HB2  sing N N 245 
MET CB  HB3  sing N N 246 
MET CG  SD   sing N N 247 
MET CG  HG2  sing N N 248 
MET CG  HG3  sing N N 249 
MET SD  CE   sing N N 250 
MET CE  HE1  sing N N 251 
MET CE  HE2  sing N N 252 
MET CE  HE3  sing N N 253 
MET OXT HXT  sing N N 254 
PHE N   CA   sing N N 255 
PHE N   H    sing N N 256 
PHE N   H2   sing N N 257 
PHE CA  C    sing N N 258 
PHE CA  CB   sing N N 259 
PHE CA  HA   sing N N 260 
PHE C   O    doub N N 261 
PHE C   OXT  sing N N 262 
PHE CB  CG   sing N N 263 
PHE CB  HB2  sing N N 264 
PHE CB  HB3  sing N N 265 
PHE CG  CD1  doub Y N 266 
PHE CG  CD2  sing Y N 267 
PHE CD1 CE1  sing Y N 268 
PHE CD1 HD1  sing N N 269 
PHE CD2 CE2  doub Y N 270 
PHE CD2 HD2  sing N N 271 
PHE CE1 CZ   doub Y N 272 
PHE CE1 HE1  sing N N 273 
PHE CE2 CZ   sing Y N 274 
PHE CE2 HE2  sing N N 275 
PHE CZ  HZ   sing N N 276 
PHE OXT HXT  sing N N 277 
PRO N   CA   sing N N 278 
PRO N   CD   sing N N 279 
PRO N   H    sing N N 280 
PRO CA  C    sing N N 281 
PRO CA  CB   sing N N 282 
PRO CA  HA   sing N N 283 
PRO C   O    doub N N 284 
PRO C   OXT  sing N N 285 
PRO CB  CG   sing N N 286 
PRO CB  HB2  sing N N 287 
PRO CB  HB3  sing N N 288 
PRO CG  CD   sing N N 289 
PRO CG  HG2  sing N N 290 
PRO CG  HG3  sing N N 291 
PRO CD  HD2  sing N N 292 
PRO CD  HD3  sing N N 293 
PRO OXT HXT  sing N N 294 
SER N   CA   sing N N 295 
SER N   H    sing N N 296 
SER N   H2   sing N N 297 
SER CA  C    sing N N 298 
SER CA  CB   sing N N 299 
SER CA  HA   sing N N 300 
SER C   O    doub N N 301 
SER C   OXT  sing N N 302 
SER CB  OG   sing N N 303 
SER CB  HB2  sing N N 304 
SER CB  HB3  sing N N 305 
SER OG  HG   sing N N 306 
SER OXT HXT  sing N N 307 
THR N   CA   sing N N 308 
THR N   H    sing N N 309 
THR N   H2   sing N N 310 
THR CA  C    sing N N 311 
THR CA  CB   sing N N 312 
THR CA  HA   sing N N 313 
THR C   O    doub N N 314 
THR C   OXT  sing N N 315 
THR CB  OG1  sing N N 316 
THR CB  CG2  sing N N 317 
THR CB  HB   sing N N 318 
THR OG1 HG1  sing N N 319 
THR CG2 HG21 sing N N 320 
THR CG2 HG22 sing N N 321 
THR CG2 HG23 sing N N 322 
THR OXT HXT  sing N N 323 
TRP N   CA   sing N N 324 
TRP N   H    sing N N 325 
TRP N   H2   sing N N 326 
TRP CA  C    sing N N 327 
TRP CA  CB   sing N N 328 
TRP CA  HA   sing N N 329 
TRP C   O    doub N N 330 
TRP C   OXT  sing N N 331 
TRP CB  CG   sing N N 332 
TRP CB  HB2  sing N N 333 
TRP CB  HB3  sing N N 334 
TRP CG  CD1  doub Y N 335 
TRP CG  CD2  sing Y N 336 
TRP CD1 NE1  sing Y N 337 
TRP CD1 HD1  sing N N 338 
TRP CD2 CE2  doub Y N 339 
TRP CD2 CE3  sing Y N 340 
TRP NE1 CE2  sing Y N 341 
TRP NE1 HE1  sing N N 342 
TRP CE2 CZ2  sing Y N 343 
TRP CE3 CZ3  doub Y N 344 
TRP CE3 HE3  sing N N 345 
TRP CZ2 CH2  doub Y N 346 
TRP CZ2 HZ2  sing N N 347 
TRP CZ3 CH2  sing Y N 348 
TRP CZ3 HZ3  sing N N 349 
TRP CH2 HH2  sing N N 350 
TRP OXT HXT  sing N N 351 
TYR N   CA   sing N N 352 
TYR N   H    sing N N 353 
TYR N   H2   sing N N 354 
TYR CA  C    sing N N 355 
TYR CA  CB   sing N N 356 
TYR CA  HA   sing N N 357 
TYR C   O    doub N N 358 
TYR C   OXT  sing N N 359 
TYR CB  CG   sing N N 360 
TYR CB  HB2  sing N N 361 
TYR CB  HB3  sing N N 362 
TYR CG  CD1  doub Y N 363 
TYR CG  CD2  sing Y N 364 
TYR CD1 CE1  sing Y N 365 
TYR CD1 HD1  sing N N 366 
TYR CD2 CE2  doub Y N 367 
TYR CD2 HD2  sing N N 368 
TYR CE1 CZ   doub Y N 369 
TYR CE1 HE1  sing N N 370 
TYR CE2 CZ   sing Y N 371 
TYR CE2 HE2  sing N N 372 
TYR CZ  OH   sing N N 373 
TYR OH  HH   sing N N 374 
TYR OXT HXT  sing N N 375 
VAL N   CA   sing N N 376 
VAL N   H    sing N N 377 
VAL N   H2   sing N N 378 
VAL CA  C    sing N N 379 
VAL CA  CB   sing N N 380 
VAL CA  HA   sing N N 381 
VAL C   O    doub N N 382 
VAL C   OXT  sing N N 383 
VAL CB  CG1  sing N N 384 
VAL CB  CG2  sing N N 385 
VAL CB  HB   sing N N 386 
VAL CG1 HG11 sing N N 387 
VAL CG1 HG12 sing N N 388 
VAL CG1 HG13 sing N N 389 
VAL CG2 HG21 sing N N 390 
VAL CG2 HG22 sing N N 391 
VAL CG2 HG23 sing N N 392 
VAL OXT HXT  sing N N 393 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-09-20 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8WG9 
_em_admin.last_update        2024-11-27 
_em_admin.map_release_date   2024-11-27 
_em_admin.title              'mGlu2-mGlu4 heterodimer bound mGlu4 agonist E7P' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     NONE 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         52 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'FEI FALCON IV (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'        ? 2  ? ? 1 ? ? 
MASKING                    ? 3  ? ? ? ? ? 
'CTF CORRECTION'           ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'       ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'     ? 6  ? ? ? ? ? 
'MODEL FITTING'            ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'         ? 8  ? ? ? ? ? 
OTHER                      ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ? ? 
CLASSIFICATION             ? 12 1 ? ? ? ? 
RECONSTRUCTION             ? 13 1 ? ? ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'National Natural Science Foundation of China (NSFC)' 
_pdbx_audit_support.country                China 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    8WG9 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N N   . ASN A 1 9   ? 189.527 215.472 94.901  1.00 27.19  ? 41   ASN B N   1 
ATOM   2     C CA  . ASN A 1 9   ? 189.851 214.118 95.398  1.00 27.19  ? 41   ASN B CA  1 
ATOM   3     C C   . ASN A 1 9   ? 191.273 214.028 95.928  1.00 27.19  ? 41   ASN B C   1 
ATOM   4     O O   . ASN A 1 9   ? 191.436 214.016 97.139  1.00 27.19  ? 41   ASN B O   1 
ATOM   5     C CB  . ASN A 1 9   ? 189.522 212.998 94.394  1.00 36.17  ? 41   ASN B CB  1 
ATOM   6     C CG  . ASN A 1 9   ? 188.032 212.924 94.088  1.00 36.17  ? 41   ASN B CG  1 
ATOM   7     O OD1 . ASN A 1 9   ? 187.258 213.772 94.496  1.00 36.17  ? 41   ASN B OD1 1 
ATOM   8     N ND2 . ASN A 1 9   ? 187.582 211.931 93.359  1.00 36.17  ? 41   ASN B ND2 1 
ATOM   9     N N   . SER A 1 10  ? 192.313 213.950 95.095  1.00 28.40  ? 42   SER B N   1 
ATOM   10    C CA  . SER A 1 10  ? 193.681 213.680 95.575  1.00 28.40  ? 42   SER B CA  1 
ATOM   11    C C   . SER A 1 10  ? 194.752 214.209 94.635  1.00 28.40  ? 42   SER B C   1 
ATOM   12    O O   . SER A 1 10  ? 194.473 214.409 93.456  1.00 28.40  ? 42   SER B O   1 
ATOM   13    C CB  . SER A 1 10  ? 193.877 212.173 95.756  1.00 37.83  ? 42   SER B CB  1 
ATOM   14    O OG  . SER A 1 10  ? 193.698 211.491 94.528  1.00 37.83  ? 42   SER B OG  1 
ATOM   15    N N   . ILE A 1 11  ? 195.975 214.416 95.139  1.00 27.58  ? 43   ILE B N   1 
ATOM   16    C CA  . ILE A 1 11  ? 197.076 214.857 94.290  1.00 27.58  ? 43   ILE B CA  1 
ATOM   17    C C   . ILE A 1 11  ? 197.958 213.707 93.872  1.00 27.58  ? 43   ILE B C   1 
ATOM   18    O O   . ILE A 1 11  ? 198.452 212.946 94.708  1.00 27.58  ? 43   ILE B O   1 
ATOM   19    C CB  . ILE A 1 11  ? 197.979 215.870 94.983  1.00 39.20  ? 43   ILE B CB  1 
ATOM   20    C CG1 . ILE A 1 11  ? 197.208 217.096 95.401  1.00 39.20  ? 43   ILE B CG1 1 
ATOM   21    C CG2 . ILE A 1 11  ? 199.110 216.261 94.052  1.00 39.20  ? 43   ILE B CG2 1 
ATOM   22    C CD1 . ILE A 1 11  ? 197.976 218.024 96.347  1.00 39.20  ? 43   ILE B CD1 1 
ATOM   23    N N   . ARG A 1 12  ? 198.176 213.603 92.565  1.00 20.45  ? 44   ARG B N   1 
ATOM   24    C CA  . ARG A 1 12  ? 199.005 212.555 91.989  1.00 20.45  ? 44   ARG B CA  1 
ATOM   25    C C   . ARG A 1 12  ? 200.227 213.114 91.267  1.00 20.45  ? 44   ARG B C   1 
ATOM   26    O O   . ARG A 1 12  ? 200.123 213.706 90.189  1.00 20.45  ? 44   ARG B O   1 
ATOM   27    C CB  . ARG A 1 12  ? 198.183 211.726 91.026  1.00 28.72  ? 44   ARG B CB  1 
ATOM   28    C CG  . ARG A 1 12  ? 197.012 211.028 91.681  1.00 28.72  ? 44   ARG B CG  1 
ATOM   29    C CD  . ARG A 1 12  ? 196.154 210.297 90.713  1.00 28.72  ? 44   ARG B CD  1 
ATOM   30    N NE  . ARG A 1 12  ? 195.531 211.198 89.740  1.00 28.72  ? 44   ARG B NE  1 
ATOM   31    C CZ  . ARG A 1 12  ? 194.435 211.971 89.963  1.00 28.72  ? 44   ARG B CZ  1 
ATOM   32    N NH1 . ARG A 1 12  ? 193.964 212.728 88.984  1.00 28.72  ? 44   ARG B NH1 1 
ATOM   33    N NH2 . ARG A 1 12  ? 193.839 211.983 91.140  1.00 28.72  ? 44   ARG B NH2 1 
ATOM   34    N N   . ILE A 1 13  ? 201.389 212.969 91.891  1.00 18.90  ? 45   ILE B N   1 
ATOM   35    C CA  . ILE A 1 13  ? 202.633 213.494 91.350  1.00 18.90  ? 45   ILE B CA  1 
ATOM   36    C C   . ILE A 1 13  ? 203.526 212.391 90.845  1.00 18.90  ? 45   ILE B C   1 
ATOM   37    O O   . ILE A 1 13  ? 203.927 211.503 91.596  1.00 18.90  ? 45   ILE B O   1 
ATOM   38    C CB  . ILE A 1 13  ? 203.363 214.342 92.400  1.00 26.86  ? 45   ILE B CB  1 
ATOM   39    C CG1 . ILE A 1 13  ? 202.485 215.516 92.721  1.00 26.86  ? 45   ILE B CG1 1 
ATOM   40    C CG2 . ILE A 1 13  ? 204.756 214.756 91.929  1.00 26.86  ? 45   ILE B CG2 1 
ATOM   41    C CD1 . ILE A 1 13  ? 202.872 216.335 93.912  1.00 26.86  ? 45   ILE B CD1 1 
ATOM   42    N N   . ASP A 1 14  ? 203.883 212.482 89.582  1.00 24.88  ? 46   ASP B N   1 
ATOM   43    C CA  . ASP A 1 14  ? 204.725 211.490 88.955  1.00 24.88  ? 46   ASP B CA  1 
ATOM   44    C C   . ASP A 1 14  ? 206.148 211.524 89.464  1.00 24.88  ? 46   ASP B C   1 
ATOM   45    O O   . ASP A 1 14  ? 206.655 212.560 89.892  1.00 24.88  ? 46   ASP B O   1 
ATOM   46    C CB  . ASP A 1 14  ? 204.732 211.685 87.450  1.00 31.68  ? 46   ASP B CB  1 
ATOM   47    C CG  . ASP A 1 14  ? 203.430 211.289 86.803  1.00 31.68  ? 46   ASP B CG  1 
ATOM   48    O OD1 . ASP A 1 14  ? 202.659 210.582 87.406  1.00 31.68  ? 46   ASP B OD1 1 
ATOM   49    O OD2 . ASP A 1 14  ? 203.206 211.716 85.706  1.00 31.68  ? 46   ASP B OD2 1 
ATOM   50    N N   . GLY A 1 15  ? 206.792 210.380 89.373  1.00 22.71  ? 47   GLY B N   1 
ATOM   51    C CA  . GLY A 1 15  ? 208.180 210.206 89.738  1.00 22.71  ? 47   GLY B CA  1 
ATOM   52    C C   . GLY A 1 15  ? 208.560 208.783 89.420  1.00 22.71  ? 47   GLY B C   1 
ATOM   53    O O   . GLY A 1 15  ? 207.762 208.040 88.847  1.00 22.71  ? 47   GLY B O   1 
ATOM   54    N N   . ASP A 1 16  ? 209.774 208.404 89.766  1.00 24.33  ? 48   ASP B N   1 
ATOM   55    C CA  . ASP A 1 16  ? 210.289 207.089 89.487  1.00 24.33  ? 48   ASP B CA  1 
ATOM   56    C C   . ASP A 1 16  ? 209.878 206.154 90.623  1.00 24.33  ? 48   ASP B C   1 
ATOM   57    O O   . ASP A 1 16  ? 209.532 204.992 90.405  1.00 24.33  ? 48   ASP B O   1 
ATOM   58    C CB  . ASP A 1 16  ? 211.793 207.224 89.330  1.00 30.98  ? 48   ASP B CB  1 
ATOM   59    C CG  . ASP A 1 16  ? 212.189 208.050 88.118  1.00 30.98  ? 48   ASP B CG  1 
ATOM   60    O OD1 . ASP A 1 16  ? 211.822 207.706 87.018  1.00 30.98  ? 48   ASP B OD1 1 
ATOM   61    O OD2 . ASP A 1 16  ? 212.837 209.070 88.308  1.00 30.98  ? 48   ASP B OD2 1 
ATOM   62    N N   . ILE A 1 17  ? 209.846 206.693 91.838  1.00 15.64  ? 49   ILE B N   1 
ATOM   63    C CA  . ILE A 1 17  ? 209.353 205.935 92.985  1.00 15.64  ? 49   ILE B CA  1 
ATOM   64    C C   . ILE A 1 17  ? 208.345 206.896 93.586  1.00 15.64  ? 49   ILE B C   1 
ATOM   65    O O   . ILE A 1 17  ? 208.516 208.099 93.411  1.00 15.64  ? 49   ILE B O   1 
ATOM   66    C CB  . ILE A 1 17  ? 210.457 205.508 93.993  1.00 22.23  ? 49   ILE B CB  1 
ATOM   67    C CG1 . ILE A 1 17  ? 211.102 206.716 94.655  1.00 22.23  ? 49   ILE B CG1 1 
ATOM   68    C CG2 . ILE A 1 17  ? 211.508 204.687 93.242  1.00 22.23  ? 49   ILE B CG2 1 
ATOM   69    C CD1 . ILE A 1 17  ? 212.088 206.395 95.814  1.00 22.23  ? 49   ILE B CD1 1 
ATOM   70    N N   . THR A 1 18  ? 207.367 206.425 94.345  1.00 16.32  ? 50   THR B N   1 
ATOM   71    C CA  . THR A 1 18  ? 206.367 207.355 94.883  1.00 16.32  ? 50   THR B CA  1 
ATOM   72    C C   . THR A 1 18  ? 206.275 207.364 96.405  1.00 16.32  ? 50   THR B C   1 
ATOM   73    O O   . THR A 1 18  ? 206.258 206.309 97.042  1.00 16.32  ? 50   THR B O   1 
ATOM   74    C CB  . THR A 1 18  ? 204.974 206.991 94.311  1.00 22.34  ? 50   THR B CB  1 
ATOM   75    O OG1 . THR A 1 18  ? 204.991 207.059 92.881  1.00 22.34  ? 50   THR B OG1 1 
ATOM   76    C CG2 . THR A 1 18  ? 203.928 207.939 94.809  1.00 22.34  ? 50   THR B CG2 1 
ATOM   77    N N   . LEU A 1 19  ? 206.098 208.529 97.036  1.00 13.83  ? 51   LEU B N   1 
ATOM   78    C CA  . LEU A 1 19  ? 205.825 208.615 98.475  1.00 13.83  ? 51   LEU B CA  1 
ATOM   79    C C   . LEU A 1 19  ? 204.451 209.220 98.788  1.00 13.83  ? 51   LEU B C   1 
ATOM   80    O O   . LEU A 1 19  ? 204.108 210.314 98.364  1.00 13.83  ? 51   LEU B O   1 
ATOM   81    C CB  . LEU A 1 19  ? 207.018 209.325 99.117  1.00 19.66  ? 51   LEU B CB  1 
ATOM   82    C CG  . LEU A 1 19  ? 206.914 209.645 100.609 1.00 19.66  ? 51   LEU B CG  1 
ATOM   83    C CD1 . LEU A 1 19  ? 206.478 208.442 101.424 1.00 19.66  ? 51   LEU B CD1 1 
ATOM   84    C CD2 . LEU A 1 19  ? 208.295 210.042 101.124 1.00 19.66  ? 51   LEU B CD2 1 
ATOM   85    N N   . GLY A 1 20  ? 203.628 208.500 99.537  1.00 17.34  ? 52   GLY B N   1 
ATOM   86    C CA  . GLY A 1 20  ? 202.384 209.058 100.043 1.00 17.34  ? 52   GLY B CA  1 
ATOM   87    C C   . GLY A 1 20  ? 202.576 210.165 101.076 1.00 17.34  ? 52   GLY B C   1 
ATOM   88    O O   . GLY A 1 20  ? 203.611 210.251 101.730 1.00 17.34  ? 52   GLY B O   1 
ATOM   89    N N   . GLY A 1 21  ? 201.523 210.945 101.290 1.00 18.16  ? 53   GLY B N   1 
ATOM   90    C CA  . GLY A 1 21  ? 201.390 211.999 102.285 1.00 18.16  ? 53   GLY B CA  1 
ATOM   91    C C   . GLY A 1 21  ? 199.927 212.164 102.704 1.00 18.16  ? 53   GLY B C   1 
ATOM   92    O O   . GLY A 1 21  ? 199.032 212.058 101.875 1.00 18.16  ? 53   GLY B O   1 
ATOM   93    N N   . LEU A 1 22  ? 199.695 212.544 103.960 1.00 18.76  ? 54   LEU B N   1 
ATOM   94    C CA  . LEU A 1 22  ? 198.365 212.696 104.547 1.00 18.76  ? 54   LEU B CA  1 
ATOM   95    C C   . LEU A 1 22  ? 198.231 213.928 105.487 1.00 18.76  ? 54   LEU B C   1 
ATOM   96    O O   . LEU A 1 22  ? 199.100 214.171 106.323 1.00 18.76  ? 54   LEU B O   1 
ATOM   97    C CB  . LEU A 1 22  ? 198.140 211.346 105.230 1.00 26.66  ? 54   LEU B CB  1 
ATOM   98    C CG  . LEU A 1 22  ? 196.774 211.134 105.845 1.00 26.66  ? 54   LEU B CG  1 
ATOM   99    C CD1 . LEU A 1 22  ? 195.664 211.337 104.823 1.00 26.66  ? 54   LEU B CD1 1 
ATOM   100   C CD2 . LEU A 1 22  ? 196.681 209.699 106.326 1.00 26.66  ? 54   LEU B CD2 1 
ATOM   101   N N   . PHE A 1 23  ? 197.170 214.744 105.351 1.00 21.61  ? 55   PHE B N   1 
ATOM   102   C CA  . PHE A 1 23  ? 196.997 216.001 106.111 1.00 21.61  ? 55   PHE B CA  1 
ATOM   103   C C   . PHE A 1 23  ? 195.536 216.419 106.255 1.00 21.61  ? 55   PHE B C   1 
ATOM   104   O O   . PHE A 1 23  ? 194.754 216.144 105.351 1.00 21.61  ? 55   PHE B O   1 
ATOM   105   C CB  . PHE A 1 23  ? 197.702 217.150 105.402 1.00 29.22  ? 55   PHE B CB  1 
ATOM   106   C CG  . PHE A 1 23  ? 199.130 216.833 105.112 1.00 29.22  ? 55   PHE B CG  1 
ATOM   107   C CD1 . PHE A 1 23  ? 199.478 216.105 103.966 1.00 29.22  ? 55   PHE B CD1 1 
ATOM   108   C CD2 . PHE A 1 23  ? 200.113 217.172 106.036 1.00 29.22  ? 55   PHE B CD2 1 
ATOM   109   C CE1 . PHE A 1 23  ? 200.788 215.638 103.801 1.00 29.22  ? 55   PHE B CE1 1 
ATOM   110   C CE2 . PHE A 1 23  ? 201.435 216.756 105.835 1.00 29.22  ? 55   PHE B CE2 1 
ATOM   111   C CZ  . PHE A 1 23  ? 201.767 215.942 104.751 1.00 29.22  ? 55   PHE B CZ  1 
ATOM   112   N N   . PRO A 1 24  ? 195.137 217.123 107.324 1.00 19.58  ? 56   PRO B N   1 
ATOM   113   C CA  . PRO A 1 24  ? 193.776 217.617 107.470 1.00 19.58  ? 56   PRO B CA  1 
ATOM   114   C C   . PRO A 1 24  ? 193.627 218.873 106.629 1.00 19.58  ? 56   PRO B C   1 
ATOM   115   O O   . PRO A 1 24  ? 193.877 219.974 107.101 1.00 19.58  ? 56   PRO B O   1 
ATOM   116   C CB  . PRO A 1 24  ? 193.589 217.835 108.974 1.00 33.46  ? 56   PRO B CB  1 
ATOM   117   C CG  . PRO A 1 24  ? 194.995 218.170 109.456 1.00 33.46  ? 56   PRO B CG  1 
ATOM   118   C CD  . PRO A 1 24  ? 195.915 217.401 108.514 1.00 33.46  ? 56   PRO B CD  1 
ATOM   119   N N   . VAL A 1 25  ? 193.298 218.716 105.353 1.00 22.72  ? 57   VAL B N   1 
ATOM   120   C CA  . VAL A 1 25  ? 192.956 219.850 104.520 1.00 22.72  ? 57   VAL B CA  1 
ATOM   121   C C   . VAL A 1 25  ? 191.582 220.350 104.941 1.00 22.72  ? 57   VAL B C   1 
ATOM   122   O O   . VAL A 1 25  ? 191.499 221.463 105.451 1.00 22.72  ? 57   VAL B O   1 
ATOM   123   C CB  . VAL A 1 25  ? 193.100 219.526 103.038 1.00 31.99  ? 57   VAL B CB  1 
ATOM   124   C CG1 . VAL A 1 25  ? 192.520 220.622 102.162 1.00 31.99  ? 57   VAL B CG1 1 
ATOM   125   C CG2 . VAL A 1 25  ? 194.577 219.328 102.698 1.00 31.99  ? 57   VAL B CG2 1 
ATOM   126   N N   . HIS A 1 26  ? 190.528 219.545 104.880 1.00 24.03  ? 58   HIS B N   1 
ATOM   127   C CA  . HIS A 1 26  ? 189.325 219.854 105.660 1.00 24.03  ? 58   HIS B CA  1 
ATOM   128   C C   . HIS A 1 26  ? 189.500 219.510 107.153 1.00 24.03  ? 58   HIS B C   1 
ATOM   129   O O   . HIS A 1 26  ? 190.376 218.729 107.517 1.00 24.03  ? 58   HIS B O   1 
ATOM   130   C CB  . HIS A 1 26  ? 188.110 219.123 105.094 1.00 31.92  ? 58   HIS B CB  1 
ATOM   131   C CG  . HIS A 1 26  ? 187.717 219.518 103.696 1.00 31.92  ? 58   HIS B CG  1 
ATOM   132   N ND1 . HIS A 1 26  ? 188.306 219.099 102.537 1.00 31.92  ? 58   HIS B ND1 1 
ATOM   133   C CD2 . HIS A 1 26  ? 186.678 220.324 103.331 1.00 31.92  ? 58   HIS B CD2 1 
ATOM   134   C CE1 . HIS A 1 26  ? 187.624 219.594 101.496 1.00 31.92  ? 58   HIS B CE1 1 
ATOM   135   N NE2 . HIS A 1 26  ? 186.598 220.342 101.933 1.00 31.92  ? 58   HIS B NE2 1 
ATOM   136   N N   . GLY A 1 27  ? 188.635 220.041 108.026 1.00 33.65  ? 59   GLY B N   1 
ATOM   137   C CA  . GLY A 1 27  ? 188.389 219.502 109.377 1.00 33.65  ? 59   GLY B CA  1 
ATOM   138   C C   . GLY A 1 27  ? 187.534 218.231 109.343 1.00 33.65  ? 59   GLY B C   1 
ATOM   139   O O   . GLY A 1 27  ? 187.457 217.570 108.313 1.00 33.65  ? 59   GLY B O   1 
ATOM   140   N N   . ARG A 1 28  ? 186.816 217.903 110.421 1.00 54.50  ? 60   ARG B N   1 
ATOM   141   C CA  . ARG A 1 28  ? 185.613 217.042 110.308 1.00 54.50  ? 60   ARG B CA  1 
ATOM   142   C C   . ARG A 1 28  ? 184.383 217.841 109.838 1.00 54.50  ? 60   ARG B C   1 
ATOM   143   O O   . ARG A 1 28  ? 184.529 218.983 109.412 1.00 54.50  ? 60   ARG B O   1 
ATOM   144   C CB  . ARG A 1 28  ? 185.388 216.224 111.585 1.00 76.54  ? 60   ARG B CB  1 
ATOM   145   C CG  . ARG A 1 28  ? 185.021 217.065 112.800 1.00 76.54  ? 60   ARG B CG  1 
ATOM   146   C CD  . ARG A 1 28  ? 184.982 216.167 114.036 1.00 76.54  ? 60   ARG B CD  1 
ATOM   147   N NE  . ARG A 1 28  ? 184.590 216.913 115.240 1.00 76.54  ? 60   ARG B NE  1 
ATOM   148   C CZ  . ARG A 1 28  ? 185.287 217.845 115.865 1.00 76.54  ? 60   ARG B CZ  1 
ATOM   149   N NH1 . ARG A 1 28  ? 184.807 218.446 116.907 1.00 76.54  ? 60   ARG B NH1 1 
ATOM   150   N NH2 . ARG A 1 28  ? 186.480 218.207 115.485 1.00 76.54  ? 60   ARG B NH2 1 
ATOM   151   N N   . GLY A 1 29  ? 183.182 217.265 109.869 1.00 72.98  ? 61   GLY B N   1 
ATOM   152   C CA  . GLY A 1 29  ? 181.951 217.940 109.431 1.00 72.98  ? 61   GLY B CA  1 
ATOM   153   C C   . GLY A 1 29  ? 180.665 217.132 109.646 1.00 72.98  ? 61   GLY B C   1 
ATOM   154   O O   . GLY A 1 29  ? 180.628 216.223 110.474 1.00 72.98  ? 61   GLY B O   1 
ATOM   155   N N   . SER A 1 30  ? 179.608 217.470 108.906 1.00 100.54 ? 62   SER B N   1 
ATOM   156   C CA  . SER A 1 30  ? 178.292 216.814 108.944 1.00 100.54 ? 62   SER B CA  1 
ATOM   157   C C   . SER A 1 30  ? 178.285 215.400 108.337 1.00 100.54 ? 62   SER B C   1 
ATOM   158   O O   . SER A 1 30  ? 179.267 214.929 107.772 1.00 100.54 ? 62   SER B O   1 
ATOM   159   C CB  . SER A 1 30  ? 177.270 217.694 108.210 1.00 133.92 ? 62   SER B CB  1 
ATOM   160   O OG  . SER A 1 30  ? 177.489 217.695 106.808 1.00 133.92 ? 62   SER B OG  1 
ATOM   161   N N   . GLU A 1 31  ? 177.150 214.708 108.415 1.00 95.87  ? 63   GLU B N   1 
ATOM   162   C CA  . GLU A 1 31  ? 176.955 213.369 107.843 1.00 95.87  ? 63   GLU B CA  1 
ATOM   163   C C   . GLU A 1 31  ? 177.106 213.352 106.314 1.00 95.87  ? 63   GLU B C   1 
ATOM   164   O O   . GLU A 1 31  ? 177.696 212.430 105.760 1.00 95.87  ? 63   GLU B O   1 
ATOM   165   C CB  . GLU A 1 31  ? 175.561 212.825 108.213 1.00 128.66 ? 63   GLU B CB  1 
ATOM   166   C CG  . GLU A 1 31  ? 175.279 212.719 109.723 1.00 128.66 ? 63   GLU B CG  1 
ATOM   167   C CD  . GLU A 1 31  ? 174.638 213.968 110.359 1.00 128.66 ? 63   GLU B CD  1 
ATOM   168   O OE1 . GLU A 1 31  ? 174.849 215.106 109.882 1.00 128.66 ? 63   GLU B OE1 1 
ATOM   169   O OE2 . GLU A 1 31  ? 173.924 213.810 111.373 1.00 128.66 ? 63   GLU B OE2 1 
ATOM   170   N N   . GLY A 1 32  ? 176.598 214.375 105.619 1.00 92.05  ? 64   GLY B N   1 
ATOM   171   C CA  . GLY A 1 32  ? 176.677 214.485 104.155 1.00 92.05  ? 64   GLY B CA  1 
ATOM   172   C C   . GLY A 1 32  ? 178.030 214.991 103.644 1.00 92.05  ? 64   GLY B C   1 
ATOM   173   O O   . GLY A 1 32  ? 178.420 214.692 102.515 1.00 92.05  ? 64   GLY B O   1 
ATOM   174   N N   . LYS A 1 33  ? 178.765 215.723 104.485 1.00 81.04  ? 65   LYS B N   1 
ATOM   175   C CA  . LYS A 1 33  ? 180.123 216.210 104.230 1.00 81.04  ? 65   LYS B CA  1 
ATOM   176   C C   . LYS A 1 33  ? 180.901 216.175 105.553 1.00 81.04  ? 65   LYS B C   1 
ATOM   177   O O   . LYS A 1 33  ? 180.916 217.176 106.266 1.00 81.04  ? 65   LYS B O   1 
ATOM   178   C CB  . LYS A 1 33  ? 180.048 217.625 103.619 1.00 120.51 ? 65   LYS B CB  1 
ATOM   179   C CG  . LYS A 1 33  ? 181.427 218.197 103.234 1.00 120.51 ? 65   LYS B CG  1 
ATOM   180   C CD  . LYS A 1 33  ? 181.872 217.843 101.803 1.00 120.51 ? 65   LYS B CD  1 
ATOM   181   C CE  . LYS A 1 33  ? 183.341 218.186 101.473 1.00 120.51 ? 65   LYS B CE  1 
ATOM   182   N NZ  . LYS A 1 33  ? 183.700 219.604 101.744 1.00 120.51 ? 65   LYS B NZ  1 
ATOM   183   N N   . PRO A 1 34  ? 181.603 215.074 105.876 1.00 69.70  ? 66   PRO B N   1 
ATOM   184   C CA  . PRO A 1 34  ? 182.366 214.923 107.123 1.00 69.70  ? 66   PRO B CA  1 
ATOM   185   C C   . PRO A 1 34  ? 183.663 215.746 107.128 1.00 69.70  ? 66   PRO B C   1 
ATOM   186   O O   . PRO A 1 34  ? 184.665 215.329 107.700 1.00 69.70  ? 66   PRO B O   1 
ATOM   187   C CB  . PRO A 1 34  ? 182.592 213.413 107.260 1.00 119.10 ? 66   PRO B CB  1 
ATOM   188   C CG  . PRO A 1 34  ? 182.668 212.946 105.813 1.00 119.10 ? 66   PRO B CG  1 
ATOM   189   C CD  . PRO A 1 34  ? 181.659 213.845 105.104 1.00 119.10 ? 66   PRO B CD  1 
ATOM   190   N N   . CYS A 1 35  ? 183.650 216.898 106.454 1.00 60.47  ? 67   CYS B N   1 
ATOM   191   C CA  . CYS A 1 35  ? 184.782 217.635 105.914 1.00 60.47  ? 67   CYS B CA  1 
ATOM   192   C C   . CYS A 1 35  ? 184.344 219.107 105.681 1.00 60.47  ? 67   CYS B C   1 
ATOM   193   O O   . CYS A 1 35  ? 184.013 219.482 104.557 1.00 60.47  ? 67   CYS B O   1 
ATOM   194   C CB  . CYS A 1 35  ? 185.164 216.948 104.586 1.00 78.36  ? 67   CYS B CB  1 
ATOM   195   S SG  . CYS A 1 35  ? 185.489 215.162 104.604 1.00 78.36  ? 67   CYS B SG  1 
ATOM   196   N N   . GLY A 1 36  ? 184.247 219.921 106.738 1.00 43.66  ? 68   GLY B N   1 
ATOM   197   C CA  . GLY A 1 36  ? 183.667 221.276 106.719 1.00 43.66  ? 68   GLY B CA  1 
ATOM   198   C C   . GLY A 1 36  ? 184.613 222.382 106.230 1.00 43.66  ? 68   GLY B C   1 
ATOM   199   O O   . GLY A 1 36  ? 184.809 222.565 105.034 1.00 43.66  ? 68   GLY B O   1 
ATOM   200   N N   . GLU A 1 37  ? 185.180 223.163 107.141 1.00 31.08  ? 69   GLU B N   1 
ATOM   201   C CA  . GLU A 1 37  ? 186.139 224.235 106.837 1.00 31.08  ? 69   GLU B CA  1 
ATOM   202   C C   . GLU A 1 37  ? 187.553 223.714 106.542 1.00 31.08  ? 69   GLU B C   1 
ATOM   203   O O   . GLU A 1 37  ? 187.945 222.640 106.998 1.00 31.08  ? 69   GLU B O   1 
ATOM   204   C CB  . GLU A 1 37  ? 186.212 225.231 108.005 1.00 40.96  ? 69   GLU B CB  1 
ATOM   205   C CG  . GLU A 1 37  ? 184.901 225.974 108.302 1.00 40.96  ? 69   GLU B CG  1 
ATOM   206   C CD  . GLU A 1 37  ? 183.823 225.163 109.049 1.00 40.96  ? 69   GLU B CD  1 
ATOM   207   O OE1 . GLU A 1 37  ? 184.123 224.078 109.593 1.00 40.96  ? 69   GLU B OE1 1 
ATOM   208   O OE2 . GLU A 1 37  ? 182.662 225.632 109.106 1.00 40.96  ? 69   GLU B OE2 1 
ATOM   209   N N   . LEU A 1 38  ? 188.358 224.496 105.826 1.00 25.52  ? 70   LEU B N   1 
ATOM   210   C CA  . LEU A 1 38  ? 189.754 224.161 105.570 1.00 25.52  ? 70   LEU B CA  1 
ATOM   211   C C   . LEU A 1 38  ? 190.636 224.537 106.762 1.00 25.52  ? 70   LEU B C   1 
ATOM   212   O O   . LEU A 1 38  ? 190.773 225.712 107.090 1.00 25.52  ? 70   LEU B O   1 
ATOM   213   C CB  . LEU A 1 38  ? 190.205 224.840 104.273 1.00 36.27  ? 70   LEU B CB  1 
ATOM   214   C CG  . LEU A 1 38  ? 191.360 224.114 103.567 1.00 36.27  ? 70   LEU B CG  1 
ATOM   215   C CD1 . LEU A 1 38  ? 191.560 224.698 102.175 1.00 36.27  ? 70   LEU B CD1 1 
ATOM   216   C CD2 . LEU A 1 38  ? 192.707 224.212 104.274 1.00 36.27  ? 70   LEU B CD2 1 
ATOM   217   N N   . LYS A 1 39  ? 191.279 223.563 107.406 1.00 24.21  ? 71   LYS B N   1 
ATOM   218   C CA  . LYS A 1 39  ? 192.239 223.806 108.496 1.00 24.21  ? 71   LYS B CA  1 
ATOM   219   C C   . LYS A 1 39  ? 193.615 224.120 107.931 1.00 24.21  ? 71   LYS B C   1 
ATOM   220   O O   . LYS A 1 39  ? 194.562 223.343 108.029 1.00 24.21  ? 71   LYS B O   1 
ATOM   221   C CB  . LYS A 1 39  ? 192.240 222.642 109.493 1.00 34.63  ? 71   LYS B CB  1 
ATOM   222   C CG  . LYS A 1 39  ? 190.880 222.480 110.181 1.00 34.63  ? 71   LYS B CG  1 
ATOM   223   C CD  . LYS A 1 39  ? 190.528 223.608 111.162 1.00 34.63  ? 71   LYS B CD  1 
ATOM   224   C CE  . LYS A 1 39  ? 189.038 223.532 111.507 1.00 34.63  ? 71   LYS B CE  1 
ATOM   225   N NZ  . LYS A 1 39  ? 188.622 224.522 112.531 1.00 34.63  ? 71   LYS B NZ  1 
ATOM   226   N N   . LYS A 1 40  ? 193.723 225.292 107.316 1.00 28.82  ? 72   LYS B N   1 
ATOM   227   C CA  . LYS A 1 40  ? 194.879 225.731 106.570 1.00 28.82  ? 72   LYS B CA  1 
ATOM   228   C C   . LYS A 1 40  ? 196.157 225.717 107.358 1.00 28.82  ? 72   LYS B C   1 
ATOM   229   O O   . LYS A 1 40  ? 197.226 225.406 106.822 1.00 28.82  ? 72   LYS B O   1 
ATOM   230   C CB  . LYS A 1 40  ? 194.604 227.121 106.008 1.00 42.86  ? 72   LYS B CB  1 
ATOM   231   C CG  . LYS A 1 40  ? 194.514 228.244 107.038 1.00 42.86  ? 72   LYS B CG  1 
ATOM   232   C CD  . LYS A 1 40  ? 194.103 229.526 106.364 1.00 42.86  ? 72   LYS B CD  1 
ATOM   233   C CE  . LYS A 1 40  ? 194.238 230.779 107.249 1.00 42.86  ? 72   LYS B CE  1 
ATOM   234   N NZ  . LYS A 1 40  ? 193.355 230.758 108.473 1.00 42.86  ? 72   LYS B NZ  1 
ATOM   235   N N   . GLU A 1 41  ? 196.057 225.904 108.670 1.00 32.33  ? 73   GLU B N   1 
ATOM   236   C CA  . GLU A 1 41  ? 197.145 225.960 109.651 1.00 32.33  ? 73   GLU B CA  1 
ATOM   237   C C   . GLU A 1 41  ? 197.665 224.607 110.159 1.00 32.33  ? 73   GLU B C   1 
ATOM   238   O O   . GLU A 1 41  ? 198.695 224.576 110.833 1.00 32.33  ? 73   GLU B O   1 
ATOM   239   C CB  . GLU A 1 41  ? 196.743 226.813 110.865 1.00 42.61  ? 73   GLU B CB  1 
ATOM   240   C CG  . GLU A 1 41  ? 195.954 228.095 110.571 1.00 42.61  ? 73   GLU B CG  1 
ATOM   241   C CD  . GLU A 1 41  ? 194.438 227.881 110.411 1.00 42.61  ? 73   GLU B CD  1 
ATOM   242   O OE1 . GLU A 1 41  ? 193.979 226.733 110.218 1.00 42.61  ? 73   GLU B OE1 1 
ATOM   243   O OE2 . GLU A 1 41  ? 193.711 228.896 110.410 1.00 42.61  ? 73   GLU B OE2 1 
ATOM   244   N N   . LYS A 1 42  ? 196.991 223.489 109.866 1.00 27.23  ? 74   LYS B N   1 
ATOM   245   C CA  . LYS A 1 42  ? 197.629 222.158 109.901 1.00 27.23  ? 74   LYS B CA  1 
ATOM   246   C C   . LYS A 1 42  ? 197.859 221.611 108.496 1.00 27.23  ? 74   LYS B C   1 
ATOM   247   O O   . LYS A 1 42  ? 198.866 220.970 108.263 1.00 27.23  ? 74   LYS B O   1 
ATOM   248   C CB  . LYS A 1 42  ? 196.811 221.148 110.720 1.00 38.95  ? 74   LYS B CB  1 
ATOM   249   N N   . GLY A 1 43  ? 196.923 221.860 107.587 1.00 23.82  ? 75   GLY B N   1 
ATOM   250   C CA  . GLY A 1 43  ? 196.775 221.273 106.264 1.00 23.82  ? 75   GLY B CA  1 
ATOM   251   C C   . GLY A 1 43  ? 197.636 221.949 105.205 1.00 23.82  ? 75   GLY B C   1 
ATOM   252   O O   . GLY A 1 43  ? 198.853 221.787 105.187 1.00 23.82  ? 75   GLY B O   1 
ATOM   253   N N   . ILE A 1 44  ? 197.003 222.688 104.289 1.00 29.14  ? 76   ILE B N   1 
ATOM   254   C CA  . ILE A 1 44  ? 197.689 223.244 103.136 1.00 29.14  ? 76   ILE B CA  1 
ATOM   255   C C   . ILE A 1 44  ? 198.953 224.048 103.424 1.00 29.14  ? 76   ILE B C   1 
ATOM   256   O O   . ILE A 1 44  ? 199.845 224.103 102.572 1.00 29.14  ? 76   ILE B O   1 
ATOM   257   C CB  . ILE A 1 44  ? 196.700 224.001 102.259 1.00 41.42  ? 76   ILE B CB  1 
ATOM   258   C CG1 . ILE A 1 44  ? 196.080 225.120 103.073 1.00 41.42  ? 76   ILE B CG1 1 
ATOM   259   C CG2 . ILE A 1 44  ? 195.686 223.001 101.685 1.00 41.42  ? 76   ILE B CG2 1 
ATOM   260   C CD1 . ILE A 1 44  ? 195.222 226.044 102.334 1.00 41.42  ? 76   ILE B CD1 1 
ATOM   261   N N   . HIS A 1 45  ? 199.083 224.697 104.597 1.00 29.72  ? 77   HIS B N   1 
ATOM   262   C CA  . HIS A 1 45  ? 200.352 225.326 104.985 1.00 29.72  ? 77   HIS B CA  1 
ATOM   263   C C   . HIS A 1 45  ? 201.454 224.274 104.909 1.00 29.72  ? 77   HIS B C   1 
ATOM   264   O O   . HIS A 1 45  ? 202.421 224.376 104.161 1.00 29.72  ? 77   HIS B O   1 
ATOM   265   C CB  . HIS A 1 45  ? 200.364 225.829 106.445 1.00 39.47  ? 77   HIS B CB  1 
ATOM   266   C CG  . HIS A 1 45  ? 199.611 227.065 106.852 1.00 39.47  ? 77   HIS B CG  1 
ATOM   267   N ND1 . HIS A 1 45  ? 199.712 227.657 108.088 1.00 39.47  ? 77   HIS B ND1 1 
ATOM   268   C CD2 . HIS A 1 45  ? 198.667 227.762 106.150 1.00 39.47  ? 77   HIS B CD2 1 
ATOM   269   C CE1 . HIS A 1 45  ? 198.847 228.680 108.133 1.00 39.47  ? 77   HIS B CE1 1 
ATOM   270   N NE2 . HIS A 1 45  ? 198.173 228.777 106.978 1.00 39.47  ? 77   HIS B NE2 1 
ATOM   271   N N   . ARG A 1 46  ? 201.277 223.214 105.687 1.00 29.71  ? 78   ARG B N   1 
ATOM   272   C CA  . ARG A 1 46  ? 202.233 222.130 105.794 1.00 29.71  ? 78   ARG B CA  1 
ATOM   273   C C   . ARG A 1 46  ? 202.316 221.358 104.491 1.00 29.71  ? 78   ARG B C   1 
ATOM   274   O O   . ARG A 1 46  ? 203.389 220.880 104.146 1.00 29.71  ? 78   ARG B O   1 
ATOM   275   C CB  . ARG A 1 46  ? 201.803 221.219 106.935 1.00 41.73  ? 78   ARG B CB  1 
ATOM   276   N N   . LEU A 1 47  ? 201.228 221.252 103.731 1.00 52.02  ? 79   LEU B N   1 
ATOM   277   C CA  . LEU A 1 47  ? 201.301 220.517 102.495 1.00 52.02  ? 79   LEU B CA  1 
ATOM   278   C C   . LEU A 1 47  ? 202.209 221.174 101.523 1.00 52.02  ? 79   LEU B C   1 
ATOM   279   O O   . LEU A 1 47  ? 203.019 220.495 100.891 1.00 52.02  ? 79   LEU B O   1 
ATOM   280   C CB  . LEU A 1 47  ? 199.950 220.408 101.833 1.00 73.94  ? 79   LEU B CB  1 
ATOM   281   C CG  . LEU A 1 47  ? 199.920 219.779 100.442 1.00 73.94  ? 79   LEU B CG  1 
ATOM   282   C CD1 . LEU A 1 47  ? 200.471 218.403 100.460 1.00 73.94  ? 79   LEU B CD1 1 
ATOM   283   C CD2 . LEU A 1 47  ? 198.492 219.786 99.960  1.00 73.94  ? 79   LEU B CD2 1 
ATOM   284   N N   . GLU A 1 48  ? 202.093 222.488 101.356 1.00 43.94  ? 80   GLU B N   1 
ATOM   285   C CA  . GLU A 1 48  ? 202.984 223.072 100.396 1.00 43.94  ? 80   GLU B CA  1 
ATOM   286   C C   . GLU A 1 48  ? 204.397 222.834 100.855 1.00 43.94  ? 80   GLU B C   1 
ATOM   287   O O   . GLU A 1 48  ? 205.266 222.571 100.034 1.00 43.94  ? 80   GLU B O   1 
ATOM   288   C CB  . GLU A 1 48  ? 202.767 224.554 100.159 1.00 57.91  ? 80   GLU B CB  1 
ATOM   289   C CG  . GLU A 1 48  ? 203.636 225.048 98.983  1.00 57.91  ? 80   GLU B CG  1 
ATOM   290   C CD  . GLU A 1 48  ? 203.469 226.450 98.617  1.00 57.91  ? 80   GLU B CD  1 
ATOM   291   O OE1 . GLU A 1 48  ? 202.980 227.204 99.402  1.00 57.91  ? 80   GLU B OE1 1 
ATOM   292   O OE2 . GLU A 1 48  ? 203.797 226.774 97.506  1.00 57.91  ? 80   GLU B OE2 1 
ATOM   293   N N   . ALA A 1 49  ? 204.652 222.928 102.161 1.00 30.39  ? 81   ALA B N   1 
ATOM   294   C CA  . ALA A 1 49  ? 205.989 222.703 102.652 1.00 30.39  ? 81   ALA B CA  1 
ATOM   295   C C   . ALA A 1 49  ? 206.490 221.319 102.340 1.00 30.39  ? 81   ALA B C   1 
ATOM   296   O O   . ALA A 1 49  ? 207.663 221.145 101.996 1.00 30.39  ? 81   ALA B O   1 
ATOM   297   C CB  . ALA A 1 49  ? 206.010 222.905 104.108 1.00 41.06  ? 81   ALA B CB  1 
ATOM   298   N N   . MET A 1 50  ? 205.652 220.305 102.484 1.00 29.71  ? 82   MET B N   1 
ATOM   299   C CA  . MET A 1 50  ? 206.039 218.961 102.106 1.00 29.71  ? 82   MET B CA  1 
ATOM   300   C C   . MET A 1 50  ? 206.377 218.927 100.617 1.00 29.71  ? 82   MET B C   1 
ATOM   301   O O   . MET A 1 50  ? 207.406 218.400 100.218 1.00 29.71  ? 82   MET B O   1 
ATOM   302   C CB  . MET A 1 50  ? 204.906 218.003 102.487 1.00 41.33  ? 82   MET B CB  1 
ATOM   303   C CG  . MET A 1 50  ? 205.261 216.526 102.261 1.00 41.33  ? 82   MET B CG  1 
ATOM   304   S SD  . MET A 1 50  ? 205.226 215.922 100.552 1.00 41.33  ? 82   MET B SD  1 
ATOM   305   C CE  . MET A 1 50  ? 203.459 216.033 100.191 1.00 41.33  ? 82   MET B CE  1 
ATOM   306   N N   . LEU A 1 51  ? 205.558 219.549 99.783  1.00 52.02  ? 83   LEU B N   1 
ATOM   307   C CA  . LEU A 1 51  ? 205.762 219.521 98.349  1.00 52.02  ? 83   LEU B CA  1 
ATOM   308   C C   . LEU A 1 51  ? 207.030 220.279 97.998  1.00 52.02  ? 83   LEU B C   1 
ATOM   309   O O   . LEU A 1 51  ? 207.754 219.901 97.079  1.00 52.02  ? 83   LEU B O   1 
ATOM   310   C CB  . LEU A 1 51  ? 204.542 220.122 97.642  1.00 73.94  ? 83   LEU B CB  1 
ATOM   311   C CG  . LEU A 1 51  ? 203.203 219.309 97.772  1.00 73.94  ? 83   LEU B CG  1 
ATOM   312   C CD1 . LEU A 1 51  ? 202.040 220.120 97.180  1.00 73.94  ? 83   LEU B CD1 1 
ATOM   313   C CD2 . LEU A 1 51  ? 203.315 217.985 97.064  1.00 73.94  ? 83   LEU B CD2 1 
ATOM   314   N N   . PHE A 1 52  ? 207.295 221.345 98.728  1.00 29.08  ? 84   PHE B N   1 
ATOM   315   C CA  . PHE A 1 52  ? 208.491 222.143 98.591  1.00 29.08  ? 84   PHE B CA  1 
ATOM   316   C C   . PHE A 1 52  ? 209.677 221.249 98.855  1.00 29.08  ? 84   PHE B C   1 
ATOM   317   O O   . PHE A 1 52  ? 210.615 221.187 98.059  1.00 29.08  ? 84   PHE B O   1 
ATOM   318   C CB  . PHE A 1 52  ? 208.414 223.313 99.561  1.00 39.33  ? 84   PHE B CB  1 
ATOM   319   C CG  . PHE A 1 52  ? 209.603 224.154 99.751  1.00 39.33  ? 84   PHE B CG  1 
ATOM   320   C CD1 . PHE A 1 52  ? 209.996 225.062 98.810  1.00 39.33  ? 84   PHE B CD1 1 
ATOM   321   C CD2 . PHE A 1 52  ? 210.307 224.076 100.951 1.00 39.33  ? 84   PHE B CD2 1 
ATOM   322   C CE1 . PHE A 1 52  ? 211.071 225.882 99.037  1.00 39.33  ? 84   PHE B CE1 1 
ATOM   323   C CE2 . PHE A 1 52  ? 211.380 224.900 101.182 1.00 39.33  ? 84   PHE B CE2 1 
ATOM   324   C CZ  . PHE A 1 52  ? 211.758 225.808 100.217 1.00 39.33  ? 84   PHE B CZ  1 
ATOM   325   N N   . ALA A 1 53  ? 209.621 220.535 99.979  1.00 24.23  ? 85   ALA B N   1 
ATOM   326   C CA  . ALA A 1 53  ? 210.663 219.615 100.336 1.00 24.23  ? 85   ALA B CA  1 
ATOM   327   C C   . ALA A 1 53  ? 210.793 218.522 99.300  1.00 24.23  ? 85   ALA B C   1 
ATOM   328   O O   . ALA A 1 53  ? 211.895 218.177 98.907  1.00 24.23  ? 85   ALA B O   1 
ATOM   329   C CB  . ALA A 1 53  ? 210.360 219.025 101.676 1.00 32.73  ? 85   ALA B CB  1 
ATOM   330   N N   . LEU A 1 54  ? 209.678 218.063 98.750  1.00 20.22  ? 86   LEU B N   1 
ATOM   331   C CA  . LEU A 1 54  ? 209.700 217.016 97.754  1.00 20.22  ? 86   LEU B CA  1 
ATOM   332   C C   . LEU A 1 54  ? 210.490 217.487 96.549  1.00 20.22  ? 86   LEU B C   1 
ATOM   333   O O   . LEU A 1 54  ? 211.356 216.760 96.042  1.00 20.22  ? 86   LEU B O   1 
ATOM   334   C CB  . LEU A 1 54  ? 208.257 216.675 97.354  1.00 28.74  ? 86   LEU B CB  1 
ATOM   335   C CG  . LEU A 1 54  ? 208.002 215.591 96.298  1.00 28.74  ? 86   LEU B CG  1 
ATOM   336   C CD1 . LEU A 1 54  ? 208.523 214.239 96.771  1.00 28.74  ? 86   LEU B CD1 1 
ATOM   337   C CD2 . LEU A 1 54  ? 206.490 215.549 96.020  1.00 28.74  ? 86   LEU B CD2 1 
ATOM   338   N N   . ASP A 1 55  ? 210.249 218.722 96.109  1.00 21.96  ? 87   ASP B N   1 
ATOM   339   C CA  . ASP A 1 55  ? 210.992 219.236 94.977  1.00 21.96  ? 87   ASP B CA  1 
ATOM   340   C C   . ASP A 1 55  ? 212.460 219.387 95.333  1.00 21.96  ? 87   ASP B C   1 
ATOM   341   O O   . ASP A 1 55  ? 213.318 219.065 94.517  1.00 21.96  ? 87   ASP B O   1 
ATOM   342   C CB  . ASP A 1 55  ? 210.451 220.592 94.533  1.00 27.96  ? 87   ASP B CB  1 
ATOM   343   C CG  . ASP A 1 55  ? 209.107 220.544 93.800  1.00 27.96  ? 87   ASP B CG  1 
ATOM   344   O OD1 . ASP A 1 55  ? 208.719 219.505 93.322  1.00 27.96  ? 87   ASP B OD1 1 
ATOM   345   O OD2 . ASP A 1 55  ? 208.488 221.573 93.712  1.00 27.96  ? 87   ASP B OD2 1 
ATOM   346   N N   . ARG A 1 56  ? 212.751 219.813 96.560  1.00 20.83  ? 88   ARG B N   1 
ATOM   347   C CA  . ARG A 1 56  ? 214.128 219.979 97.003  1.00 20.83  ? 88   ARG B CA  1 
ATOM   348   C C   . ARG A 1 56  ? 214.856 218.652 97.085  1.00 20.83  ? 88   ARG B C   1 
ATOM   349   O O   . ARG A 1 56  ? 216.056 218.594 96.834  1.00 20.83  ? 88   ARG B O   1 
ATOM   350   C CB  . ARG A 1 56  ? 214.186 220.684 98.323  1.00 29.25  ? 88   ARG B CB  1 
ATOM   351   C CG  . ARG A 1 56  ? 213.798 222.125 98.256  1.00 29.25  ? 88   ARG B CG  1 
ATOM   352   C CD  . ARG A 1 56  ? 213.753 222.709 99.566  1.00 29.25  ? 88   ARG B CD  1 
ATOM   353   N NE  . ARG A 1 56  ? 215.075 222.779 100.159 1.00 29.25  ? 88   ARG B NE  1 
ATOM   354   C CZ  . ARG A 1 56  ? 215.335 222.900 101.469 1.00 29.25  ? 88   ARG B CZ  1 
ATOM   355   N NH1 . ARG A 1 56  ? 216.596 222.980 101.870 1.00 29.25  ? 88   ARG B NH1 1 
ATOM   356   N NH2 . ARG A 1 56  ? 214.355 222.941 102.339 1.00 29.25  ? 88   ARG B NH2 1 
ATOM   357   N N   . ILE A 1 57  ? 214.136 217.596 97.442  1.00 30.39  ? 89   ILE B N   1 
ATOM   358   C CA  . ILE A 1 57  ? 214.688 216.258 97.490  1.00 30.39  ? 89   ILE B CA  1 
ATOM   359   C C   . ILE A 1 57  ? 215.047 215.857 96.083  1.00 30.39  ? 89   ILE B C   1 
ATOM   360   O O   . ILE A 1 57  ? 216.155 215.403 95.827  1.00 30.39  ? 89   ILE B O   1 
ATOM   361   C CB  . ILE A 1 57  ? 213.681 215.262 98.112  1.00 43.19  ? 89   ILE B CB  1 
ATOM   362   C CG1 . ILE A 1 57  ? 213.529 215.582 99.617  1.00 43.19  ? 89   ILE B CG1 1 
ATOM   363   C CG2 . ILE A 1 57  ? 214.102 213.807 97.843  1.00 43.19  ? 89   ILE B CG2 1 
ATOM   364   C CD1 . ILE A 1 57  ? 212.356 214.941 100.332 1.00 43.19  ? 89   ILE B CD1 1 
ATOM   365   N N   . ASN A 1 58  ? 214.137 216.103 95.151  1.00 19.39  ? 90   ASN B N   1 
ATOM   366   C CA  . ASN A 1 58  ? 214.372 215.764 93.764  1.00 19.39  ? 90   ASN B CA  1 
ATOM   367   C C   . ASN A 1 58  ? 215.489 216.599 93.164  1.00 19.39  ? 90   ASN B C   1 
ATOM   368   O O   . ASN A 1 58  ? 216.240 216.131 92.307  1.00 19.39  ? 90   ASN B O   1 
ATOM   369   C CB  . ASN A 1 58  ? 213.092 215.937 92.984  1.00 25.79  ? 90   ASN B CB  1 
ATOM   370   C CG  . ASN A 1 58  ? 212.142 214.851 93.292  1.00 25.79  ? 90   ASN B CG  1 
ATOM   371   O OD1 . ASN A 1 58  ? 212.587 213.785 93.709  1.00 25.79  ? 90   ASN B OD1 1 
ATOM   372   N ND2 . ASN A 1 58  ? 210.863 215.072 93.118  1.00 25.79  ? 90   ASN B ND2 1 
ATOM   373   N N   . ASN A 1 59  ? 215.659 217.806 93.675  1.00 24.41  ? 91   ASN B N   1 
ATOM   374   C CA  . ASN A 1 59  ? 216.685 218.702 93.204  1.00 24.41  ? 91   ASN B CA  1 
ATOM   375   C C   . ASN A 1 59  ? 217.983 218.585 94.000  1.00 24.41  ? 91   ASN B C   1 
ATOM   376   O O   . ASN A 1 59  ? 218.886 219.396 93.799  1.00 24.41  ? 91   ASN B O   1 
ATOM   377   C CB  . ASN A 1 59  ? 216.185 220.127 93.266  1.00 32.47  ? 91   ASN B CB  1 
ATOM   378   C CG  . ASN A 1 59  ? 215.062 220.383 92.316  1.00 32.47  ? 91   ASN B CG  1 
ATOM   379   O OD1 . ASN A 1 59  ? 214.995 219.812 91.221  1.00 32.47  ? 91   ASN B OD1 1 
ATOM   380   N ND2 . ASN A 1 59  ? 214.162 221.247 92.708  1.00 32.47  ? 91   ASN B ND2 1 
ATOM   381   N N   . ASP A 1 60  ? 218.078 217.615 94.918  1.00 23.11  ? 92   ASP B N   1 
ATOM   382   C CA  . ASP A 1 60  ? 219.266 217.400 95.733  1.00 23.11  ? 92   ASP B CA  1 
ATOM   383   C C   . ASP A 1 60  ? 220.153 216.328 95.086  1.00 23.11  ? 92   ASP B C   1 
ATOM   384   O O   . ASP A 1 60  ? 219.781 215.155 95.076  1.00 23.11  ? 92   ASP B O   1 
ATOM   385   C CB  . ASP A 1 60  ? 218.874 216.981 97.154  1.00 29.43  ? 92   ASP B CB  1 
ATOM   386   C CG  . ASP A 1 60  ? 220.069 216.774 98.091  1.00 29.43  ? 92   ASP B CG  1 
ATOM   387   O OD1 . ASP A 1 60  ? 221.183 216.619 97.599  1.00 29.43  ? 92   ASP B OD1 1 
ATOM   388   O OD2 . ASP A 1 60  ? 219.878 216.791 99.291  1.00 29.43  ? 92   ASP B OD2 1 
ATOM   389   N N   . PRO A 1 61  ? 221.320 216.664 94.505  1.00 28.18  ? 93   PRO B N   1 
ATOM   390   C CA  . PRO A 1 61  ? 222.193 215.744 93.796  1.00 28.18  ? 93   PRO B CA  1 
ATOM   391   C C   . PRO A 1 61  ? 222.708 214.595 94.653  1.00 28.18  ? 93   PRO B C   1 
ATOM   392   O O   . PRO A 1 61  ? 223.162 213.581 94.123  1.00 28.18  ? 93   PRO B O   1 
ATOM   393   C CB  . PRO A 1 61  ? 223.385 216.632 93.410  1.00 48.15  ? 93   PRO B CB  1 
ATOM   394   C CG  . PRO A 1 61  ? 222.847 218.032 93.408  1.00 48.15  ? 93   PRO B CG  1 
ATOM   395   C CD  . PRO A 1 61  ? 221.828 218.056 94.523  1.00 48.15  ? 93   PRO B CD  1 
ATOM   396   N N   . ASP A 1 62  ? 222.683 214.768 95.977  1.00 31.12  ? 94   ASP B N   1 
ATOM   397   C CA  . ASP A 1 62  ? 223.206 213.755 96.872  1.00 31.12  ? 94   ASP B CA  1 
ATOM   398   C C   . ASP A 1 62  ? 222.138 212.914 97.554  1.00 31.12  ? 94   ASP B C   1 
ATOM   399   O O   . ASP A 1 62  ? 222.472 212.104 98.421  1.00 31.12  ? 94   ASP B O   1 
ATOM   400   C CB  . ASP A 1 62  ? 224.064 214.428 97.942  1.00 39.63  ? 94   ASP B CB  1 
ATOM   401   C CG  . ASP A 1 62  ? 225.336 215.089 97.388  1.00 39.63  ? 94   ASP B CG  1 
ATOM   402   O OD1 . ASP A 1 62  ? 225.933 214.565 96.472  1.00 39.63  ? 94   ASP B OD1 1 
ATOM   403   O OD2 . ASP A 1 62  ? 225.707 216.120 97.903  1.00 39.63  ? 94   ASP B OD2 1 
ATOM   404   N N   . LEU A 1 63  ? 220.870 213.103 97.202  1.00 24.74  ? 95   LEU B N   1 
ATOM   405   C CA  . LEU A 1 63  ? 219.809 212.350 97.859  1.00 24.74  ? 95   LEU B CA  1 
ATOM   406   C C   . LEU A 1 63  ? 218.943 211.637 96.841  1.00 24.74  ? 95   LEU B C   1 
ATOM   407   O O   . LEU A 1 63  ? 218.347 212.272 95.978  1.00 24.74  ? 95   LEU B O   1 
ATOM   408   C CB  . LEU A 1 63  ? 218.985 213.305 98.741  1.00 35.16  ? 95   LEU B CB  1 
ATOM   409   C CG  . LEU A 1 63  ? 217.747 212.747 99.464  1.00 35.16  ? 95   LEU B CG  1 
ATOM   410   C CD1 . LEU A 1 63  ? 218.146 211.672 100.422 1.00 35.16  ? 95   LEU B CD1 1 
ATOM   411   C CD2 . LEU A 1 63  ? 217.076 213.888 100.230 1.00 35.16  ? 95   LEU B CD2 1 
ATOM   412   N N   . LEU A 1 64  ? 218.865 210.308 96.944  1.00 27.21  ? 96   LEU B N   1 
ATOM   413   C CA  . LEU A 1 64  ? 218.116 209.516 95.981  1.00 27.21  ? 96   LEU B CA  1 
ATOM   414   C C   . LEU A 1 64  ? 218.572 209.939 94.588  1.00 27.21  ? 96   LEU B C   1 
ATOM   415   O O   . LEU A 1 64  ? 217.763 210.398 93.778  1.00 27.21  ? 96   LEU B O   1 
ATOM   416   C CB  . LEU A 1 64  ? 216.598 209.764 96.127  1.00 38.67  ? 96   LEU B CB  1 
ATOM   417   C CG  . LEU A 1 64  ? 215.972 209.464 97.497  1.00 38.67  ? 96   LEU B CG  1 
ATOM   418   C CD1 . LEU A 1 64  ? 214.503 209.868 97.480  1.00 38.67  ? 96   LEU B CD1 1 
ATOM   419   C CD2 . LEU A 1 64  ? 216.105 208.016 97.813  1.00 38.67  ? 96   LEU B CD2 1 
ATOM   420   N N   . PRO A 1 65  ? 219.870 209.795 94.270  1.00 20.74  ? 97   PRO B N   1 
ATOM   421   C CA  . PRO A 1 65  ? 220.445 210.291 93.055  1.00 20.74  ? 97   PRO B CA  1 
ATOM   422   C C   . PRO A 1 65  ? 219.793 209.669 91.861  1.00 20.74  ? 97   PRO B C   1 
ATOM   423   O O   . PRO A 1 65  ? 219.618 208.447 91.797  1.00 20.74  ? 97   PRO B O   1 
ATOM   424   C CB  . PRO A 1 65  ? 221.912 209.865 93.175  1.00 35.44  ? 97   PRO B CB  1 
ATOM   425   C CG  . PRO A 1 65  ? 221.903 208.724 94.175  1.00 35.44  ? 97   PRO B CG  1 
ATOM   426   C CD  . PRO A 1 65  ? 220.804 209.069 95.132  1.00 35.44  ? 97   PRO B CD  1 
ATOM   427   N N   . ASN A 1 66  ? 219.444 210.546 90.928  1.00 21.34  ? 98   ASN B N   1 
ATOM   428   C CA  . ASN A 1 66  ? 218.786 210.256 89.663  1.00 21.34  ? 98   ASN B CA  1 
ATOM   429   C C   . ASN A 1 66  ? 217.393 209.634 89.817  1.00 21.34  ? 98   ASN B C   1 
ATOM   430   O O   . ASN A 1 66  ? 216.849 209.092 88.852  1.00 21.34  ? 98   ASN B O   1 
ATOM   431   C CB  . ASN A 1 66  ? 219.689 209.413 88.786  1.00 28.39  ? 98   ASN B CB  1 
ATOM   432   C CG  . ASN A 1 66  ? 220.946 210.146 88.450  1.00 28.39  ? 98   ASN B CG  1 
ATOM   433   O OD1 . ASN A 1 66  ? 220.946 211.378 88.318  1.00 28.39  ? 98   ASN B OD1 1 
ATOM   434   N ND2 . ASN A 1 66  ? 222.020 209.432 88.297  1.00 28.39  ? 98   ASN B ND2 1 
ATOM   435   N N   . ILE A 1 67  ? 216.786 209.756 90.998  1.00 22.59  ? 99   ILE B N   1 
ATOM   436   C CA  . ILE A 1 67  ? 215.444 209.237 91.214  1.00 22.59  ? 99   ILE B CA  1 
ATOM   437   C C   . ILE A 1 67  ? 214.456 210.340 91.477  1.00 22.59  ? 99   ILE B C   1 
ATOM   438   O O   . ILE A 1 67  ? 214.571 211.053 92.471  1.00 22.59  ? 99   ILE B O   1 
ATOM   439   C CB  . ILE A 1 67  ? 215.408 208.335 92.460  1.00 32.11  ? 99   ILE B CB  1 
ATOM   440   C CG1 . ILE A 1 67  ? 216.339 207.181 92.286  1.00 32.11  ? 99   ILE B CG1 1 
ATOM   441   C CG2 . ILE A 1 67  ? 213.980 207.860 92.756  1.00 32.11  ? 99   ILE B CG2 1 
ATOM   442   C CD1 . ILE A 1 67  ? 216.609 206.401 93.531  1.00 32.11  ? 99   ILE B CD1 1 
ATOM   443   N N   . THR A 1 68  ? 213.429 210.440 90.666  1.00 18.91  ? 100  THR B N   1 
ATOM   444   C CA  . THR A 1 68  ? 212.443 211.441 90.979  1.00 18.91  ? 100  THR B CA  1 
ATOM   445   C C   . THR A 1 68  ? 211.510 210.815 91.989  1.00 18.91  ? 100  THR B C   1 
ATOM   446   O O   . THR A 1 68  ? 210.964 209.731 91.761  1.00 18.91  ? 100  THR B O   1 
ATOM   447   C CB  . THR A 1 68  ? 211.660 211.896 89.736  1.00 25.89  ? 100  THR B CB  1 
ATOM   448   O OG1 . THR A 1 68  ? 212.564 212.465 88.789  1.00 25.89  ? 100  THR B OG1 1 
ATOM   449   C CG2 . THR A 1 68  ? 210.605 212.947 90.128  1.00 25.89  ? 100  THR B CG2 1 
ATOM   450   N N   . LEU A 1 69  ? 211.282 211.493 93.080  1.00 14.46  ? 101  LEU B N   1 
ATOM   451   C CA  . LEU A 1 69  ? 210.360 211.007 94.060  1.00 14.46  ? 101  LEU B CA  1 
ATOM   452   C C   . LEU A 1 69  ? 209.015 211.653 93.748  1.00 14.46  ? 101  LEU B C   1 
ATOM   453   O O   . LEU A 1 69  ? 208.898 212.876 93.635  1.00 14.46  ? 101  LEU B O   1 
ATOM   454   C CB  . LEU A 1 69  ? 210.907 211.337 95.457  1.00 20.55  ? 101  LEU B CB  1 
ATOM   455   C CG  . LEU A 1 69  ? 210.090 210.923 96.689  1.00 20.55  ? 101  LEU B CG  1 
ATOM   456   C CD1 . LEU A 1 69  ? 209.974 209.441 96.733  1.00 20.55  ? 101  LEU B CD1 1 
ATOM   457   C CD2 . LEU A 1 69  ? 210.819 211.427 97.947  1.00 20.55  ? 101  LEU B CD2 1 
ATOM   458   N N   . GLY A 1 70  ? 208.021 210.827 93.494  1.00 14.69  ? 102  GLY B N   1 
ATOM   459   C CA  . GLY A 1 70  ? 206.701 211.293 93.151  1.00 14.69  ? 102  GLY B CA  1 
ATOM   460   C C   . GLY A 1 70  ? 205.921 211.345 94.426  1.00 14.69  ? 102  GLY B C   1 
ATOM   461   O O   . GLY A 1 70  ? 206.496 211.201 95.510  1.00 14.69  ? 102  GLY B O   1 
ATOM   462   N N   . ALA A 1 71  ? 204.621 211.529 94.333  1.00 19.13  ? 103  ALA B N   1 
ATOM   463   C CA  . ALA A 1 71  ? 203.848 211.606 95.548  1.00 19.13  ? 103  ALA B CA  1 
ATOM   464   C C   . ALA A 1 71  ? 202.379 211.329 95.394  1.00 19.13  ? 103  ALA B C   1 
ATOM   465   O O   . ALA A 1 71  ? 201.769 211.463 94.325  1.00 19.13  ? 103  ALA B O   1 
ATOM   466   C CB  . ALA A 1 71  ? 204.011 212.959 96.203  1.00 25.84  ? 103  ALA B CB  1 
ATOM   467   N N   . ARG A 1 72  ? 201.797 210.972 96.516  1.00 26.92  ? 104  ARG B N   1 
ATOM   468   C CA  . ARG A 1 72  ? 200.350 210.826 96.613  1.00 26.92  ? 104  ARG B CA  1 
ATOM   469   C C   . ARG A 1 72  ? 199.852 211.523 97.857  1.00 26.92  ? 104  ARG B C   1 
ATOM   470   O O   . ARG A 1 72  ? 200.215 211.146 98.976  1.00 26.92  ? 104  ARG B O   1 
ATOM   471   C CB  . ARG A 1 72  ? 199.942 209.367 96.693  1.00 37.81  ? 104  ARG B CB  1 
ATOM   472   C CG  . ARG A 1 72  ? 200.262 208.535 95.495  1.00 37.81  ? 104  ARG B CG  1 
ATOM   473   C CD  . ARG A 1 72  ? 199.438 208.864 94.319  1.00 37.81  ? 104  ARG B CD  1 
ATOM   474   N NE  . ARG A 1 72  ? 199.752 207.994 93.208  1.00 37.81  ? 104  ARG B NE  1 
ATOM   475   C CZ  . ARG A 1 72  ? 200.748 208.187 92.318  1.00 37.81  ? 104  ARG B CZ  1 
ATOM   476   N NH1 . ARG A 1 72  ? 200.918 207.303 91.355  1.00 37.81  ? 104  ARG B NH1 1 
ATOM   477   N NH2 . ARG A 1 72  ? 201.550 209.229 92.395  1.00 37.81  ? 104  ARG B NH2 1 
ATOM   478   N N   . ILE A 1 73  ? 198.978 212.496 97.688  1.00 52.02  ? 105  ILE B N   1 
ATOM   479   C CA  . ILE A 1 73  ? 198.488 213.232 98.842  1.00 52.02  ? 105  ILE B CA  1 
ATOM   480   C C   . ILE A 1 73  ? 197.009 212.990 99.026  1.00 52.02  ? 105  ILE B C   1 
ATOM   481   O O   . ILE A 1 73  ? 196.256 213.002 98.050  1.00 52.02  ? 105  ILE B O   1 
ATOM   482   C CB  . ILE A 1 73  ? 198.884 214.699 98.774  1.00 73.94  ? 105  ILE B CB  1 
ATOM   483   C CG1 . ILE A 1 73  ? 200.413 214.863 98.588  1.00 73.94  ? 105  ILE B CG1 1 
ATOM   484   C CG2 . ILE A 1 73  ? 198.447 215.346 100.083 1.00 73.94  ? 105  ILE B CG2 1 
ATOM   485   C CD1 . ILE A 1 73  ? 200.868 215.003 97.133  1.00 73.94  ? 105  ILE B CD1 1 
ATOM   486   N N   . LEU A 1 74  ? 196.603 212.840 100.278 1.00 52.02  ? 106  LEU B N   1 
ATOM   487   C CA  . LEU A 1 74  ? 195.207 212.749 100.633 1.00 52.02  ? 106  LEU B CA  1 
ATOM   488   C C   . LEU A 1 74  ? 194.857 213.652 101.803 1.00 52.02  ? 106  LEU B C   1 
ATOM   489   O O   . LEU A 1 74  ? 195.676 213.956 102.668 1.00 52.02  ? 106  LEU B O   1 
ATOM   490   C CB  . LEU A 1 74  ? 194.856 211.290 100.944 1.00 73.94  ? 106  LEU B CB  1 
ATOM   491   C CG  . LEU A 1 74  ? 193.941 210.640 99.912  1.00 73.94  ? 106  LEU B CG  1 
ATOM   492   C CD1 . LEU A 1 74  ? 193.653 209.206 100.342 1.00 73.94  ? 106  LEU B CD1 1 
ATOM   493   C CD2 . LEU A 1 74  ? 192.608 211.370 99.791  1.00 73.94  ? 106  LEU B CD2 1 
ATOM   494   N N   . ASP A 1 75  ? 193.584 214.022 101.837 1.00 32.40  ? 107  ASP B N   1 
ATOM   495   C CA  . ASP A 1 75  ? 193.010 214.852 102.877 1.00 32.40  ? 107  ASP B CA  1 
ATOM   496   C C   . ASP A 1 75  ? 192.347 213.981 103.916 1.00 32.40  ? 107  ASP B C   1 
ATOM   497   O O   . ASP A 1 75  ? 191.395 213.268 103.617 1.00 32.40  ? 107  ASP B O   1 
ATOM   498   C CB  . ASP A 1 75  ? 191.970 215.791 102.264 1.00 41.26  ? 107  ASP B CB  1 
ATOM   499   C CG  . ASP A 1 75  ? 191.213 216.612 103.315 1.00 41.26  ? 107  ASP B CG  1 
ATOM   500   O OD1 . ASP A 1 75  ? 191.630 216.668 104.490 1.00 41.26  ? 107  ASP B OD1 1 
ATOM   501   O OD2 . ASP A 1 75  ? 190.230 217.271 102.928 1.00 41.26  ? 107  ASP B OD2 1 
ATOM   502   N N   . THR A 1 76  ? 192.791 214.073 105.150 1.00 25.57  ? 108  THR B N   1 
ATOM   503   C CA  . THR A 1 76  ? 192.221 213.285 106.219 1.00 25.57  ? 108  THR B CA  1 
ATOM   504   C C   . THR A 1 76  ? 190.784 213.626 106.549 1.00 25.57  ? 108  THR B C   1 
ATOM   505   O O   . THR A 1 76  ? 190.128 212.848 107.233 1.00 25.57  ? 108  THR B O   1 
ATOM   506   C CB  . THR A 1 76  ? 193.038 213.449 107.493 1.00 35.00  ? 108  THR B CB  1 
ATOM   507   O OG1 . THR A 1 76  ? 193.058 214.737 108.017 1.00 35.00  ? 108  THR B OG1 1 
ATOM   508   C CG2 . THR A 1 76  ? 194.496 213.104 107.273 1.00 35.00  ? 108  THR B CG2 1 
ATOM   509   N N   . CYS A 1 77  ? 190.292 214.797 106.186 1.00 35.83  ? 109  CYS B N   1 
ATOM   510   C CA  . CYS A 1 77  ? 189.218 215.421 106.956 1.00 35.83  ? 109  CYS B CA  1 
ATOM   511   C C   . CYS A 1 77  ? 189.628 215.402 108.446 1.00 35.83  ? 109  CYS B C   1 
ATOM   512   O O   . CYS A 1 77  ? 190.727 215.850 108.782 1.00 35.83  ? 109  CYS B O   1 
ATOM   513   C CB  . CYS A 1 77  ? 187.845 214.825 106.588 1.00 46.43  ? 109  CYS B CB  1 
ATOM   514   S SG  . CYS A 1 77  ? 187.499 214.991 104.822 1.00 46.43  ? 109  CYS B SG  1 
ATOM   515   N N   . SER A 1 78  ? 188.865 214.802 109.359 1.00 30.00  ? 110  SER B N   1 
ATOM   516   C CA  . SER A 1 78  ? 189.416 214.470 110.688 1.00 30.00  ? 110  SER B CA  1 
ATOM   517   C C   . SER A 1 78  ? 188.760 213.243 111.311 1.00 30.00  ? 110  SER B C   1 
ATOM   518   O O   . SER A 1 78  ? 189.447 212.453 111.949 1.00 30.00  ? 110  SER B O   1 
ATOM   519   C CB  . SER A 1 78  ? 189.355 215.659 111.667 1.00 39.96  ? 110  SER B CB  1 
ATOM   520   O OG  . SER A 1 78  ? 189.718 216.894 111.079 1.00 39.96  ? 110  SER B OG  1 
ATOM   521   N N   . ARG A 1 79  ? 187.464 213.029 111.083 1.00 33.92  ? 111  ARG B N   1 
ATOM   522   C CA  . ARG A 1 79  ? 186.792 211.789 111.442 1.00 33.92  ? 111  ARG B CA  1 
ATOM   523   C C   . ARG A 1 79  ? 187.429 210.648 110.658 1.00 33.92  ? 111  ARG B C   1 
ATOM   524   O O   . ARG A 1 79  ? 187.236 210.543 109.450 1.00 33.92  ? 111  ARG B O   1 
ATOM   525   C CB  . ARG A 1 79  ? 185.313 211.922 111.107 1.00 47.64  ? 111  ARG B CB  1 
ATOM   526   N N   . ASP A 1 80  ? 188.266 209.845 111.317 1.00 30.00  ? 112  ASP B N   1 
ATOM   527   C CA  . ASP A 1 80  ? 189.307 209.066 110.643 1.00 30.00  ? 112  ASP B CA  1 
ATOM   528   C C   . ASP A 1 80  ? 188.793 207.922 109.775 1.00 30.00  ? 112  ASP B C   1 
ATOM   529   O O   . ASP A 1 80  ? 189.525 207.427 108.924 1.00 30.00  ? 112  ASP B O   1 
ATOM   530   C CB  . ASP A 1 80  ? 190.301 208.564 111.678 1.00 30.00  ? 112  ASP B CB  1 
ATOM   531   N N   . THR A 1 81  ? 187.523 207.542 109.886 1.00 23.38  ? 113  THR B N   1 
ATOM   532   C CA  . THR A 1 81  ? 186.890 206.605 108.946 1.00 23.38  ? 113  THR B CA  1 
ATOM   533   C C   . THR A 1 81  ? 187.007 207.085 107.499 1.00 23.38  ? 113  THR B C   1 
ATOM   534   O O   . THR A 1 81  ? 187.258 206.279 106.605 1.00 23.38  ? 113  THR B O   1 
ATOM   535   C CB  . THR A 1 81  ? 185.415 206.402 109.290 1.00 32.00  ? 113  THR B CB  1 
ATOM   536   O OG1 . THR A 1 81  ? 184.742 207.637 109.241 1.00 32.00  ? 113  THR B OG1 1 
ATOM   537   C CG2 . THR A 1 81  ? 185.220 205.830 110.687 1.00 32.00  ? 113  THR B CG2 1 
ATOM   538   N N   . HIS A 1 82  ? 186.963 208.402 107.268 1.00 26.67  ? 114  HIS B N   1 
ATOM   539   C CA  . HIS A 1 82  ? 187.286 209.001 105.975 1.00 26.67  ? 114  HIS B CA  1 
ATOM   540   C C   . HIS A 1 82  ? 188.727 208.694 105.563 1.00 26.67  ? 114  HIS B C   1 
ATOM   541   O O   . HIS A 1 82  ? 188.967 208.395 104.397 1.00 26.67  ? 114  HIS B O   1 
ATOM   542   C CB  . HIS A 1 82  ? 187.050 210.519 106.046 1.00 35.42  ? 114  HIS B CB  1 
ATOM   543   C CG  . HIS A 1 82  ? 187.474 211.269 104.811 1.00 35.42  ? 114  HIS B CG  1 
ATOM   544   N ND1 . HIS A 1 82  ? 186.642 211.681 103.772 1.00 35.42  ? 114  HIS B ND1 1 
ATOM   545   C CD2 . HIS A 1 82  ? 188.747 211.661 104.537 1.00 35.42  ? 114  HIS B CD2 1 
ATOM   546   C CE1 . HIS A 1 82  ? 187.434 212.337 102.908 1.00 35.42  ? 114  HIS B CE1 1 
ATOM   547   N NE2 . HIS A 1 82  ? 188.704 212.328 103.342 1.00 35.42  ? 114  HIS B NE2 1 
ATOM   548   N N   . ALA A 1 83  ? 189.685 208.717 106.488 1.00 20.07  ? 115  ALA B N   1 
ATOM   549   C CA  . ALA A 1 83  ? 191.072 208.430 106.164 1.00 20.07  ? 115  ALA B CA  1 
ATOM   550   C C   . ALA A 1 83  ? 191.199 207.049 105.555 1.00 20.07  ? 115  ALA B C   1 
ATOM   551   O O   . ALA A 1 83  ? 191.817 206.884 104.511 1.00 20.07  ? 115  ALA B O   1 
ATOM   552   C CB  . ALA A 1 83  ? 191.954 208.530 107.412 1.00 27.11  ? 115  ALA B CB  1 
ATOM   553   N N   . LEU A 1 84  ? 190.675 206.045 106.218 1.00 20.29  ? 116  LEU B N   1 
ATOM   554   C CA  . LEU A 1 84  ? 190.905 204.706 105.705 1.00 20.29  ? 116  LEU B CA  1 
ATOM   555   C C   . LEU A 1 84  ? 190.251 204.512 104.375 1.00 20.29  ? 116  LEU B C   1 
ATOM   556   O O   . LEU A 1 84  ? 190.906 204.154 103.409 1.00 20.29  ? 116  LEU B O   1 
ATOM   557   C CB  . LEU A 1 84  ? 190.404 203.656 106.698 1.00 28.84  ? 116  LEU B CB  1 
ATOM   558   C CG  . LEU A 1 84  ? 191.479 203.129 107.649 1.00 28.84  ? 116  LEU B CG  1 
ATOM   559   C CD1 . LEU A 1 84  ? 192.424 202.212 106.894 1.00 28.84  ? 116  LEU B CD1 1 
ATOM   560   C CD2 . LEU A 1 84  ? 192.252 204.276 108.279 1.00 28.84  ? 116  LEU B CD2 1 
ATOM   561   N N   . GLU A 1 85  ? 188.952 204.742 104.316 1.00 25.68  ? 117  GLU B N   1 
ATOM   562   C CA  . GLU A 1 85  ? 188.258 204.465 103.087 1.00 25.68  ? 117  GLU B CA  1 
ATOM   563   C C   . GLU A 1 85  ? 189.168 204.959 102.032 1.00 25.68  ? 117  GLU B C   1 
ATOM   564   O O   . GLU A 1 85  ? 189.450 204.282 101.054 1.00 25.68  ? 117  GLU B O   1 
ATOM   565   C CB  . GLU A 1 85  ? 186.944 205.214 103.026 1.00 33.84  ? 117  GLU B CB  1 
ATOM   566   C CG  . GLU A 1 85  ? 185.958 204.625 102.032 1.00 33.84  ? 117  GLU B CG  1 
ATOM   567   C CD  . GLU A 1 85  ? 185.431 203.267 102.463 1.00 33.84  ? 117  GLU B CD  1 
ATOM   568   O OE1 . GLU A 1 85  ? 185.507 202.951 103.669 1.00 33.84  ? 117  GLU B OE1 1 
ATOM   569   O OE2 . GLU A 1 85  ? 184.927 202.517 101.599 1.00 33.84  ? 117  GLU B OE2 1 
ATOM   570   N N   . GLN A 1 86  ? 189.655 206.160 102.244 1.00 27.96  ? 118  GLN B N   1 
ATOM   571   C CA  . GLN A 1 86  ? 190.556 206.719 101.286 1.00 27.96  ? 118  GLN B CA  1 
ATOM   572   C C   . GLN A 1 86  ? 191.778 205.858 101.220 1.00 27.96  ? 118  GLN B C   1 
ATOM   573   O O   . GLN A 1 86  ? 192.188 205.445 100.135 1.00 27.96  ? 118  GLN B O   1 
ATOM   574   C CB  . GLN A 1 86  ? 190.940 208.136 101.691 1.00 38.00  ? 118  GLN B CB  1 
ATOM   575   C CG  . GLN A 1 86  ? 189.793 209.137 101.633 1.00 38.00  ? 118  GLN B CG  1 
ATOM   576   C CD  . GLN A 1 86  ? 190.182 210.524 102.109 1.00 38.00  ? 118  GLN B CD  1 
ATOM   577   O OE1 . GLN A 1 86  ? 191.116 210.682 102.891 1.00 38.00  ? 118  GLN B OE1 1 
ATOM   578   N NE2 . GLN A 1 86  ? 189.469 211.539 101.633 1.00 38.00  ? 118  GLN B NE2 1 
ATOM   579   N N   . SER A 1 87  ? 192.362 205.569 102.367 1.00 25.59  ? 119  SER B N   1 
ATOM   580   C CA  . SER A 1 87  ? 193.595 204.843 102.338 1.00 25.59  ? 119  SER B CA  1 
ATOM   581   C C   . SER A 1 87  ? 193.410 203.703 101.387 1.00 25.59  ? 119  SER B C   1 
ATOM   582   O O   . SER A 1 87  ? 194.382 203.211 100.829 1.00 25.59  ? 119  SER B O   1 
ATOM   583   C CB  . SER A 1 87  ? 193.957 204.350 103.716 1.00 34.09  ? 119  SER B CB  1 
ATOM   584   O OG  . SER A 1 87  ? 195.311 203.940 103.740 1.00 34.09  ? 119  SER B OG  1 
ATOM   585   N N   . LEU A 1 88  ? 192.168 203.279 101.156 1.00 29.90  ? 120  LEU B N   1 
ATOM   586   C CA  . LEU A 1 88  ? 192.012 202.111 100.306 1.00 29.90  ? 120  LEU B CA  1 
ATOM   587   C C   . LEU A 1 88  ? 192.498 202.346 98.873  1.00 29.90  ? 120  LEU B C   1 
ATOM   588   O O   . LEU A 1 88  ? 192.932 201.390 98.222  1.00 29.90  ? 120  LEU B O   1 
ATOM   589   C CB  . LEU A 1 88  ? 190.552 201.657 100.249 1.00 42.50  ? 120  LEU B CB  1 
ATOM   590   C CG  . LEU A 1 88  ? 189.970 201.031 101.525 1.00 42.50  ? 120  LEU B CG  1 
ATOM   591   C CD1 . LEU A 1 88  ? 188.459 200.861 101.349 1.00 42.50  ? 120  LEU B CD1 1 
ATOM   592   C CD2 . LEU A 1 88  ? 190.635 199.649 101.789 1.00 42.50  ? 120  LEU B CD2 1 
ATOM   593   N N   . THR A 1 89  ? 192.379 203.563 98.328  1.00 32.28  ? 121  THR B N   1 
ATOM   594   C CA  . THR A 1 89  ? 192.868 203.796 96.972  1.00 32.28  ? 121  THR B CA  1 
ATOM   595   C C   . THR A 1 89  ? 194.387 203.707 97.012  1.00 32.28  ? 121  THR B C   1 
ATOM   596   O O   . THR A 1 89  ? 195.033 203.096 96.150  1.00 32.28  ? 121  THR B O   1 
ATOM   597   C CB  . THR A 1 89  ? 192.426 205.168 96.430  1.00 44.19  ? 121  THR B CB  1 
ATOM   598   O OG1 . THR A 1 89  ? 190.994 205.225 96.377  1.00 44.19  ? 121  THR B OG1 1 
ATOM   599   C CG2 . THR A 1 89  ? 192.983 205.377 95.026  1.00 44.19  ? 121  THR B CG2 1 
ATOM   600   N N   . PHE A 1 90  ? 194.942 204.316 98.050  1.00 30.73  ? 122  PHE B N   1 
ATOM   601   C CA  . PHE A 1 90  ? 196.370 204.345 98.318  1.00 30.73  ? 122  PHE B CA  1 
ATOM   602   C C   . PHE A 1 90  ? 196.897 202.919 98.457  1.00 30.73  ? 122  PHE B C   1 
ATOM   603   O O   . PHE A 1 90  ? 197.941 202.565 97.902  1.00 30.73  ? 122  PHE B O   1 
ATOM   604   C CB  . PHE A 1 90  ? 196.604 205.183 99.564  1.00 41.56  ? 122  PHE B CB  1 
ATOM   605   C CG  . PHE A 1 90  ? 197.942 205.352 99.983  1.00 41.56  ? 122  PHE B CG  1 
ATOM   606   C CD1 . PHE A 1 90  ? 198.756 206.179 99.284  1.00 41.56  ? 122  PHE B CD1 1 
ATOM   607   C CD2 . PHE A 1 90  ? 198.406 204.741 101.123 1.00 41.56  ? 122  PHE B CD2 1 
ATOM   608   C CE1 . PHE A 1 90  ? 200.012 206.391 99.684  1.00 41.56  ? 122  PHE B CE1 1 
ATOM   609   C CE2 . PHE A 1 90  ? 199.688 204.963 101.534 1.00 41.56  ? 122  PHE B CE2 1 
ATOM   610   C CZ  . PHE A 1 90  ? 200.489 205.787 100.800 1.00 41.56  ? 122  PHE B CZ  1 
ATOM   611   N N   . VAL A 1 91  ? 196.157 202.113 99.201  1.00 32.03  ? 123  VAL B N   1 
ATOM   612   C CA  . VAL A 1 91  ? 196.470 200.736 99.454  1.00 32.03  ? 123  VAL B CA  1 
ATOM   613   C C   . VAL A 1 91  ? 196.403 199.935 98.172  1.00 32.03  ? 123  VAL B C   1 
ATOM   614   O O   . VAL A 1 91  ? 197.322 199.172 97.905  1.00 32.03  ? 123  VAL B O   1 
ATOM   615   C CB  . VAL A 1 91  ? 195.577 200.151 100.563 1.00 45.11  ? 123  VAL B CB  1 
ATOM   616   C CG1 . VAL A 1 91  ? 195.775 198.661 100.689 1.00 45.11  ? 123  VAL B CG1 1 
ATOM   617   C CG2 . VAL A 1 91  ? 195.946 200.812 101.923 1.00 45.11  ? 123  VAL B CG2 1 
ATOM   618   N N   . GLN A 1 92  ? 195.400 200.135 97.320  1.00 40.18  ? 124  GLN B N   1 
ATOM   619   C CA  . GLN A 1 92  ? 195.409 199.364 96.089  1.00 40.18  ? 124  GLN B CA  1 
ATOM   620   C C   . GLN A 1 92  ? 196.688 199.659 95.289  1.00 40.18  ? 124  GLN B C   1 
ATOM   621   O O   . GLN A 1 92  ? 197.244 198.745 94.679  1.00 40.18  ? 124  GLN B O   1 
ATOM   622   C CB  . GLN A 1 92  ? 194.175 199.660 95.238  1.00 54.61  ? 124  GLN B CB  1 
ATOM   623   C CG  . GLN A 1 92  ? 194.063 198.783 93.994  1.00 54.61  ? 124  GLN B CG  1 
ATOM   624   C CD  . GLN A 1 92  ? 193.877 197.319 94.336  1.00 54.61  ? 124  GLN B CD  1 
ATOM   625   O OE1 . GLN A 1 92  ? 192.924 196.947 95.028  1.00 54.61  ? 124  GLN B OE1 1 
ATOM   626   N NE2 . GLN A 1 92  ? 194.795 196.485 93.866  1.00 54.61  ? 124  GLN B NE2 1 
ATOM   627   N N   . ALA A 1 93  ? 197.170 200.917 95.293  1.00 47.11  ? 125  ALA B N   1 
ATOM   628   C CA  . ALA A 1 93  ? 198.438 201.245 94.614  1.00 47.11  ? 125  ALA B CA  1 
ATOM   629   C C   . ALA A 1 93  ? 199.598 200.476 95.271  1.00 47.11  ? 125  ALA B C   1 
ATOM   630   O O   . ALA A 1 93  ? 200.491 199.961 94.594  1.00 47.11  ? 125  ALA B O   1 
ATOM   631   C CB  . ALA A 1 93  ? 198.713 202.741 94.671  1.00 63.64  ? 125  ALA B CB  1 
ATOM   632   N N   . LEU A 1 94  ? 199.536 200.353 96.601  1.00 41.50  ? 126  LEU B N   1 
ATOM   633   C CA  . LEU A 1 94  ? 200.516 199.591 97.399  1.00 41.50  ? 126  LEU B CA  1 
ATOM   634   C C   . LEU A 1 94  ? 200.442 198.049 97.192  1.00 41.50  ? 126  LEU B C   1 
ATOM   635   O O   . LEU A 1 94  ? 201.465 197.362 97.323  1.00 41.50  ? 126  LEU B O   1 
ATOM   636   C CB  . LEU A 1 94  ? 200.307 199.878 98.910  1.00 58.99  ? 126  LEU B CB  1 
ATOM   637   C CG  . LEU A 1 94  ? 200.636 201.308 99.430  1.00 58.99  ? 126  LEU B CG  1 
ATOM   638   C CD1 . LEU A 1 94  ? 200.144 201.474 100.816 1.00 58.99  ? 126  LEU B CD1 1 
ATOM   639   C CD2 . LEU A 1 94  ? 202.093 201.490 99.448  1.00 58.99  ? 126  LEU B CD2 1 
ATOM   640   N N   . ILE A 1 95  ? 199.233 197.522 96.888  1.00 47.57  ? 127  ILE B N   1 
ATOM   641   C CA  . ILE A 1 95  ? 198.894 196.112 96.714  1.00 47.57  ? 127  ILE B CA  1 
ATOM   642   C C   . ILE A 1 95  ? 197.614 196.049 95.871  1.00 47.57  ? 127  ILE B C   1 
ATOM   643   O O   . ILE A 1 95  ? 197.440 195.159 95.027  1.00 47.57  ? 127  ILE B O   1 
ATOM   644   C CB  . ILE A 1 95  ? 198.690 195.391 98.138  1.00 67.61  ? 127  ILE B CB  1 
ATOM   645   C CG1 . ILE A 1 95  ? 198.443 193.776 97.988  1.00 67.61  ? 127  ILE B CG1 1 
ATOM   646   C CG2 . ILE A 1 95  ? 197.514 196.080 99.027  1.00 67.61  ? 127  ILE B CG2 1 
ATOM   647   C CD1 . ILE A 1 95  ? 198.540 192.985 99.338  1.00 67.61  ? 127  ILE B CD1 1 
ATOM   648   N N   . GLU A 1 116 ? 203.266 203.252 89.436  1.00 38.86  ? 148  GLU B N   1 
ATOM   649   C CA  . GLU A 1 116 ? 202.066 203.549 90.228  1.00 38.86  ? 148  GLU B CA  1 
ATOM   650   C C   . GLU A 1 116 ? 202.174 203.134 91.724  1.00 38.86  ? 148  GLU B C   1 
ATOM   651   O O   . GLU A 1 116 ? 201.349 203.566 92.542  1.00 38.86  ? 148  GLU B O   1 
ATOM   652   C CB  . GLU A 1 116 ? 200.805 202.892 89.570  1.00 51.21  ? 148  GLU B CB  1 
ATOM   653   C CG  . GLU A 1 116 ? 200.393 203.457 88.114  1.00 51.21  ? 148  GLU B CG  1 
ATOM   654   C CD  . GLU A 1 116 ? 199.142 202.804 87.468  1.00 51.21  ? 148  GLU B CD  1 
ATOM   655   O OE1 . GLU A 1 116 ? 198.576 201.899 88.037  1.00 51.21  ? 148  GLU B OE1 1 
ATOM   656   O OE2 . GLU A 1 116 ? 198.781 203.235 86.401  1.00 51.21  ? 148  GLU B OE2 1 
ATOM   657   N N   . ARG A 1 117 ? 203.158 202.264 92.069  1.00 32.05  ? 149  ARG B N   1 
ATOM   658   C CA  . ARG A 1 117 ? 203.416 201.727 93.413  1.00 32.05  ? 149  ARG B CA  1 
ATOM   659   C C   . ARG A 1 117 ? 204.028 202.765 94.359  1.00 32.05  ? 149  ARG B C   1 
ATOM   660   O O   . ARG A 1 117 ? 204.949 203.502 93.996  1.00 32.05  ? 149  ARG B O   1 
ATOM   661   C CB  . ARG A 1 117 ? 204.354 200.523 93.347  1.00 45.01  ? 149  ARG B CB  1 
ATOM   662   C CG  . ARG A 1 117 ? 204.541 199.793 94.687  1.00 45.01  ? 149  ARG B CG  1 
ATOM   663   C CD  . ARG A 1 117 ? 205.524 198.672 94.629  1.00 45.01  ? 149  ARG B CD  1 
ATOM   664   N NE  . ARG A 1 117 ? 205.139 197.559 93.750  1.00 45.01  ? 149  ARG B NE  1 
ATOM   665   C CZ  . ARG A 1 117 ? 204.278 196.569 94.073  1.00 45.01  ? 149  ARG B CZ  1 
ATOM   666   N NH1 . ARG A 1 117 ? 204.057 195.596 93.205  1.00 45.01  ? 149  ARG B NH1 1 
ATOM   667   N NH2 . ARG A 1 117 ? 203.654 196.564 95.239  1.00 45.01  ? 149  ARG B NH2 1 
ATOM   668   N N   . VAL A 1 118 ? 203.522 202.782 95.582  1.00 18.22  ? 150  VAL B N   1 
ATOM   669   C CA  . VAL A 1 118 ? 203.996 203.665 96.633  1.00 18.22  ? 150  VAL B CA  1 
ATOM   670   C C   . VAL A 1 118 ? 204.950 202.923 97.580  1.00 18.22  ? 150  VAL B C   1 
ATOM   671   O O   . VAL A 1 118 ? 204.712 201.776 97.945  1.00 18.22  ? 150  VAL B O   1 
ATOM   672   C CB  . VAL A 1 118 ? 202.797 204.291 97.357  1.00 25.66  ? 150  VAL B CB  1 
ATOM   673   C CG1 . VAL A 1 118 ? 203.278 205.168 98.462  1.00 25.66  ? 150  VAL B CG1 1 
ATOM   674   C CG2 . VAL A 1 118 ? 201.955 205.059 96.363  1.00 25.66  ? 150  VAL B CG2 1 
ATOM   675   N N   . VAL A 1 119 ? 206.072 203.554 97.903  1.00 13.93  ? 151  VAL B N   1 
ATOM   676   C CA  . VAL A 1 119 ? 207.075 202.946 98.772  1.00 13.93  ? 151  VAL B CA  1 
ATOM   677   C C   . VAL A 1 119 ? 206.709 203.010 100.263 1.00 13.93  ? 151  VAL B C   1 
ATOM   678   O O   . VAL A 1 119 ? 207.053 202.116 101.028 1.00 13.93  ? 151  VAL B O   1 
ATOM   679   C CB  . VAL A 1 119 ? 208.461 203.582 98.504  1.00 19.62  ? 151  VAL B CB  1 
ATOM   680   C CG1 . VAL A 1 119 ? 208.594 205.005 99.128  1.00 19.62  ? 151  VAL B CG1 1 
ATOM   681   C CG2 . VAL A 1 119 ? 209.545 202.643 99.000  1.00 19.62  ? 151  VAL B CG2 1 
ATOM   682   N N   . GLY A 1 120 ? 206.018 204.055 100.699 1.00 17.57  ? 152  GLY B N   1 
ATOM   683   C CA  . GLY A 1 120 ? 205.824 204.377 102.113 1.00 17.57  ? 152  GLY B CA  1 
ATOM   684   C C   . GLY A 1 120 ? 204.887 205.562 102.271 1.00 17.57  ? 152  GLY B C   1 
ATOM   685   O O   . GLY A 1 120 ? 204.256 205.979 101.301 1.00 17.57  ? 152  GLY B O   1 
ATOM   686   N N   . VAL A 1 121 ? 204.774 206.134 103.465 1.00 26.51  ? 153  VAL B N   1 
ATOM   687   C CA  . VAL A 1 121 ? 203.880 207.273 103.660 1.00 26.51  ? 153  VAL B CA  1 
ATOM   688   C C   . VAL A 1 121 ? 204.387 208.225 104.723 1.00 26.51  ? 153  VAL B C   1 
ATOM   689   O O   . VAL A 1 121 ? 204.976 207.807 105.717 1.00 26.51  ? 153  VAL B O   1 
ATOM   690   C CB  . VAL A 1 121 ? 202.452 206.764 103.932 1.00 37.33  ? 153  VAL B CB  1 
ATOM   691   C CG1 . VAL A 1 121 ? 202.288 206.199 105.327 1.00 37.33  ? 153  VAL B CG1 1 
ATOM   692   C CG2 . VAL A 1 121 ? 201.372 207.825 103.772 1.00 37.33  ? 153  VAL B CG2 1 
ATOM   693   N N   . ILE A 1 122 ? 204.048 209.499 104.588 1.00 52.02  ? 154  ILE B N   1 
ATOM   694   C CA  . ILE A 1 122 ? 203.982 210.409 105.723 1.00 52.02  ? 154  ILE B CA  1 
ATOM   695   C C   . ILE A 1 122 ? 202.512 210.556 106.096 1.00 52.02  ? 154  ILE B C   1 
ATOM   696   O O   . ILE A 1 122 ? 201.697 210.966 105.283 1.00 52.02  ? 154  ILE B O   1 
ATOM   697   C CB  . ILE A 1 122 ? 204.657 211.723 105.348 1.00 73.94  ? 154  ILE B CB  1 
ATOM   698   C CG1 . ILE A 1 122 ? 206.136 211.517 104.976 1.00 73.94  ? 154  ILE B CG1 1 
ATOM   699   C CG2 . ILE A 1 122 ? 204.517 212.716 106.496 1.00 73.94  ? 154  ILE B CG2 1 
ATOM   700   C CD1 . ILE A 1 122 ? 206.976 210.771 106.010 1.00 73.94  ? 154  ILE B CD1 1 
ATOM   701   N N   . GLY A 1 123 ? 202.140 210.125 107.297 1.00 27.85  ? 155  GLY B N   1 
ATOM   702   C CA  . GLY A 1 123 ? 200.759 209.742 107.614 1.00 27.85  ? 155  GLY B CA  1 
ATOM   703   C C   . GLY A 1 123 ? 200.116 210.553 108.731 1.00 27.85  ? 155  GLY B C   1 
ATOM   704   O O   . GLY A 1 123 ? 199.146 211.264 108.500 1.00 27.85  ? 155  GLY B O   1 
ATOM   705   N N   . ALA A 1 124 ? 200.703 210.509 109.925 1.00 21.59  ? 156  ALA B N   1 
ATOM   706   C CA  . ALA A 1 124 ? 200.582 211.605 110.886 1.00 21.59  ? 156  ALA B CA  1 
ATOM   707   C C   . ALA A 1 124 ? 199.150 212.112 111.178 1.00 21.59  ? 156  ALA B C   1 
ATOM   708   O O   . ALA A 1 124 ? 198.244 211.310 111.371 1.00 21.59  ? 156  ALA B O   1 
ATOM   709   C CB  . ALA A 1 124 ? 201.491 212.712 110.350 1.00 29.17  ? 156  ALA B CB  1 
ATOM   710   N N   . SER A 1 125 ? 198.962 213.442 111.265 1.00 24.61  ? 157  SER B N   1 
ATOM   711   C CA  . SER A 1 125 ? 197.751 214.090 111.765 1.00 24.61  ? 157  SER B CA  1 
ATOM   712   C C   . SER A 1 125 ? 197.450 213.692 113.215 1.00 24.61  ? 157  SER B C   1 
ATOM   713   O O   . SER A 1 125 ? 198.361 213.348 113.963 1.00 24.61  ? 157  SER B O   1 
ATOM   714   C CB  . SER A 1 125 ? 196.629 213.823 110.769 1.00 32.78  ? 157  SER B CB  1 
ATOM   715   O OG  . SER A 1 125 ? 195.448 214.524 111.088 1.00 32.78  ? 157  SER B OG  1 
ATOM   716   N N   . GLY A 1 126 ? 196.195 213.789 113.649 1.00 23.89  ? 158  GLY B N   1 
ATOM   717   C CA  . GLY A 1 126 ? 195.732 213.485 115.007 1.00 23.89  ? 158  GLY B CA  1 
ATOM   718   C C   . GLY A 1 126 ? 195.748 212.010 115.400 1.00 23.89  ? 158  GLY B C   1 
ATOM   719   O O   . GLY A 1 126 ? 196.253 211.145 114.692 1.00 23.89  ? 158  GLY B O   1 
ATOM   720   N N   . SER A 1 127 ? 195.172 211.681 116.549 1.00 22.34  ? 159  SER B N   1 
ATOM   721   C CA  . SER A 1 127 ? 195.116 210.284 116.981 1.00 22.34  ? 159  SER B CA  1 
ATOM   722   C C   . SER A 1 127 ? 194.364 209.383 116.016 1.00 22.34  ? 159  SER B C   1 
ATOM   723   O O   . SER A 1 127 ? 194.990 208.585 115.330 1.00 22.34  ? 159  SER B O   1 
ATOM   724   C CB  . SER A 1 127 ? 194.558 210.137 118.383 1.00 29.76  ? 159  SER B CB  1 
ATOM   725   O OG  . SER A 1 127 ? 193.215 210.581 118.519 1.00 29.76  ? 159  SER B OG  1 
ATOM   726   N N   . SER A 1 128 ? 193.042 209.479 115.922 1.00 22.17  ? 160  SER B N   1 
ATOM   727   C CA  . SER A 1 128 ? 192.225 208.523 115.169 1.00 22.17  ? 160  SER B CA  1 
ATOM   728   C C   . SER A 1 128 ? 192.700 208.379 113.722 1.00 22.17  ? 160  SER B C   1 
ATOM   729   O O   . SER A 1 128 ? 192.827 207.277 113.208 1.00 22.17  ? 160  SER B O   1 
ATOM   730   C CB  . SER A 1 128 ? 190.768 208.955 115.250 1.00 29.53  ? 160  SER B CB  1 
ATOM   731   O OG  . SER A 1 128 ? 190.645 210.307 114.862 1.00 29.53  ? 160  SER B OG  1 
ATOM   732   N N   . VAL A 1 129 ? 193.103 209.478 113.099 1.00 18.64  ? 161  VAL B N   1 
ATOM   733   C CA  . VAL A 1 129 ? 193.717 209.480 111.780 1.00 18.64  ? 161  VAL B CA  1 
ATOM   734   C C   . VAL A 1 129 ? 194.983 208.639 111.722 1.00 18.64  ? 161  VAL B C   1 
ATOM   735   O O   . VAL A 1 129 ? 195.119 207.838 110.818 1.00 18.64  ? 161  VAL B O   1 
ATOM   736   C CB  . VAL A 1 129 ? 194.021 210.911 111.360 1.00 26.25  ? 161  VAL B CB  1 
ATOM   737   C CG1 . VAL A 1 129 ? 194.717 210.931 110.007 1.00 26.25  ? 161  VAL B CG1 1 
ATOM   738   C CG2 . VAL A 1 129 ? 192.732 211.723 111.247 1.00 26.25  ? 161  VAL B CG2 1 
ATOM   739   N N   . SER A 1 130 ? 195.921 208.768 112.645 1.00 21.24  ? 162  SER B N   1 
ATOM   740   C CA  . SER A 1 130 ? 197.147 207.991 112.587 1.00 21.24  ? 162  SER B CA  1 
ATOM   741   C C   . SER A 1 130 ? 196.937 206.554 113.013 1.00 21.24  ? 162  SER B C   1 
ATOM   742   O O   . SER A 1 130 ? 197.457 205.657 112.359 1.00 21.24  ? 162  SER B O   1 
ATOM   743   C CB  . SER A 1 130 ? 198.209 208.578 113.478 1.00 28.29  ? 162  SER B CB  1 
ATOM   744   O OG  . SER A 1 130 ? 197.718 208.727 114.785 1.00 28.29  ? 162  SER B OG  1 
ATOM   745   N N   . ILE A 1 131 ? 196.161 206.303 114.064 1.00 22.07  ? 163  ILE B N   1 
ATOM   746   C CA  . ILE A 1 131 ? 196.056 204.959 114.626 1.00 22.07  ? 163  ILE B CA  1 
ATOM   747   C C   . ILE A 1 131 ? 195.280 204.012 113.721 1.00 22.07  ? 163  ILE B C   1 
ATOM   748   O O   . ILE A 1 131 ? 195.691 202.869 113.552 1.00 22.07  ? 163  ILE B O   1 
ATOM   749   C CB  . ILE A 1 131 ? 195.523 205.001 116.066 1.00 31.37  ? 163  ILE B CB  1 
ATOM   750   C CG1 . ILE A 1 131 ? 196.146 203.860 116.873 1.00 31.37  ? 163  ILE B CG1 1 
ATOM   751   C CG2 . ILE A 1 131 ? 193.994 204.942 116.167 1.00 31.37  ? 163  ILE B CG2 1 
ATOM   752   C CD1 . ILE A 1 131 ? 196.129 204.121 118.369 1.00 31.37  ? 163  ILE B CD1 1 
ATOM   753   N N   . MET A 1 132 ? 194.219 204.478 113.065 1.00 21.99  ? 164  MET B N   1 
ATOM   754   C CA  . MET A 1 132 ? 193.570 203.635 112.084 1.00 21.99  ? 164  MET B CA  1 
ATOM   755   C C   . MET A 1 132 ? 194.563 203.283 110.996 1.00 21.99  ? 164  MET B C   1 
ATOM   756   O O   . MET A 1 132 ? 194.772 202.117 110.725 1.00 21.99  ? 164  MET B O   1 
ATOM   757   C CB  . MET A 1 132 ? 192.343 204.312 111.505 1.00 30.59  ? 164  MET B CB  1 
ATOM   758   C CG  . MET A 1 132 ? 191.273 204.553 112.555 1.00 30.59  ? 164  MET B CG  1 
ATOM   759   S SD  . MET A 1 132 ? 189.794 205.338 111.877 1.00 30.59  ? 164  MET B SD  1 
ATOM   760   C CE  . MET A 1 132 ? 188.931 203.878 111.252 1.00 30.59  ? 164  MET B CE  1 
ATOM   761   N N   . VAL A 1 133 ? 195.247 204.248 110.398 1.00 19.73  ? 165  VAL B N   1 
ATOM   762   C CA  . VAL A 1 133 ? 196.121 203.960 109.259 1.00 19.73  ? 165  VAL B CA  1 
ATOM   763   C C   . VAL A 1 133 ? 197.307 203.068 109.636 1.00 19.73  ? 165  VAL B C   1 
ATOM   764   O O   . VAL A 1 133 ? 197.623 202.155 108.882 1.00 19.73  ? 165  VAL B O   1 
ATOM   765   C CB  . VAL A 1 133 ? 196.535 205.253 108.562 1.00 27.78  ? 165  VAL B CB  1 
ATOM   766   C CG1 . VAL A 1 133 ? 197.489 205.036 107.402 1.00 27.78  ? 165  VAL B CG1 1 
ATOM   767   C CG2 . VAL A 1 133 ? 195.315 205.938 107.939 1.00 27.78  ? 165  VAL B CG2 1 
ATOM   768   N N   . ALA A 1 134 ? 197.889 203.195 110.823 1.00 16.69  ? 166  ALA B N   1 
ATOM   769   C CA  . ALA A 1 134 ? 198.974 202.340 111.282 1.00 16.69  ? 166  ALA B CA  1 
ATOM   770   C C   . ALA A 1 134 ? 198.597 200.862 111.309 1.00 16.69  ? 166  ALA B C   1 
ATOM   771   O O   . ALA A 1 134 ? 199.465 200.016 111.148 1.00 16.69  ? 166  ALA B O   1 
ATOM   772   C CB  . ALA A 1 134 ? 199.485 202.844 112.617 1.00 22.55  ? 166  ALA B CB  1 
ATOM   773   N N   . ASN A 1 135 ? 197.308 200.550 111.404 1.00 18.25  ? 167  ASN B N   1 
ATOM   774   C CA  . ASN A 1 135 ? 196.785 199.187 111.405 1.00 18.25  ? 167  ASN B CA  1 
ATOM   775   C C   . ASN A 1 135 ? 196.397 198.626 110.054 1.00 18.25  ? 167  ASN B C   1 
ATOM   776   O O   . ASN A 1 135 ? 196.047 197.452 109.973 1.00 18.25  ? 167  ASN B O   1 
ATOM   777   C CB  . ASN A 1 135 ? 195.624 199.024 112.344 1.00 24.28  ? 167  ASN B CB  1 
ATOM   778   C CG  . ASN A 1 135 ? 196.027 198.854 113.747 1.00 24.28  ? 167  ASN B CG  1 
ATOM   779   O OD1 . ASN A 1 135 ? 197.086 198.276 114.042 1.00 24.28  ? 167  ASN B OD1 1 
ATOM   780   N ND2 . ASN A 1 135 ? 195.202 199.319 114.645 1.00 24.28  ? 167  ASN B ND2 1 
ATOM   781   N N   . ILE A 1 136 ? 196.447 199.421 109.000 1.00 18.07  ? 168  ILE B N   1 
ATOM   782   C CA  . ILE A 1 136 ? 196.135 198.884 107.698 1.00 18.07  ? 168  ILE B CA  1 
ATOM   783   C C   . ILE A 1 136 ? 197.433 198.730 106.941 1.00 18.07  ? 168  ILE B C   1 
ATOM   784   O O   . ILE A 1 136 ? 197.678 197.719 106.300 1.00 18.07  ? 168  ILE B O   1 
ATOM   785   C CB  . ILE A 1 136 ? 195.110 199.737 106.891 1.00 25.68  ? 168  ILE B CB  1 
ATOM   786   C CG1 . ILE A 1 136 ? 194.550 198.863 105.780 1.00 25.68  ? 168  ILE B CG1 1 
ATOM   787   C CG2 . ILE A 1 136 ? 195.712 201.020 106.253 1.00 25.68  ? 168  ILE B CG2 1 
ATOM   788   C CD1 . ILE A 1 136 ? 193.335 199.401 105.089 1.00 25.68  ? 168  ILE B CD1 1 
ATOM   789   N N   . LEU A 1 137 ? 198.296 199.723 107.016 1.00 19.90  ? 169  LEU B N   1 
ATOM   790   C CA  . LEU A 1 137 ? 199.503 199.685 106.218 1.00 19.90  ? 169  LEU B CA  1 
ATOM   791   C C   . LEU A 1 137 ? 200.503 198.674 106.697 1.00 19.90  ? 169  LEU B C   1 
ATOM   792   O O   . LEU A 1 137 ? 201.204 198.048 105.894 1.00 19.90  ? 169  LEU B O   1 
ATOM   793   C CB  . LEU A 1 137 ? 200.152 201.048 106.211 1.00 28.28  ? 169  LEU B CB  1 
ATOM   794   C CG  . LEU A 1 137 ? 199.399 202.137 105.509 1.00 28.28  ? 169  LEU B CG  1 
ATOM   795   C CD1 . LEU A 1 137 ? 200.155 203.360 105.685 1.00 28.28  ? 169  LEU B CD1 1 
ATOM   796   C CD2 . LEU A 1 137 ? 199.223 201.850 104.041 1.00 28.28  ? 169  LEU B CD2 1 
ATOM   797   N N   . ARG A 1 138 ? 200.522 198.406 107.984 1.00 22.11  ? 170  ARG B N   1 
ATOM   798   C CA  . ARG A 1 138 ? 201.481 197.456 108.489 1.00 22.11  ? 170  ARG B CA  1 
ATOM   799   C C   . ARG A 1 138 ? 201.178 196.056 107.986 1.00 22.11  ? 170  ARG B C   1 
ATOM   800   O O   . ARG A 1 138 ? 202.053 195.197 107.931 1.00 22.11  ? 170  ARG B O   1 
ATOM   801   C CB  . ARG A 1 138 ? 201.445 197.429 109.994 1.00 31.05  ? 170  ARG B CB  1 
ATOM   802   C CG  . ARG A 1 138 ? 200.209 196.809 110.618 1.00 31.05  ? 170  ARG B CG  1 
ATOM   803   C CD  . ARG A 1 138 ? 200.225 197.031 112.077 1.00 31.05  ? 170  ARG B CD  1 
ATOM   804   N NE  . ARG A 1 138 ? 199.150 196.376 112.743 1.00 31.05  ? 170  ARG B NE  1 
ATOM   805   C CZ  . ARG A 1 138 ? 199.198 195.100 113.178 1.00 31.05  ? 170  ARG B CZ  1 
ATOM   806   N NH1 . ARG A 1 138 ? 198.141 194.589 113.793 1.00 31.05  ? 170  ARG B NH1 1 
ATOM   807   N NH2 . ARG A 1 138 ? 200.299 194.344 113.011 1.00 31.05  ? 170  ARG B NH2 1 
ATOM   808   N N   . LEU A 1 139 ? 199.951 195.814 107.545 1.00 28.22  ? 171  LEU B N   1 
ATOM   809   C CA  . LEU A 1 139 ? 199.551 194.486 107.153 1.00 28.22  ? 171  LEU B CA  1 
ATOM   810   C C   . LEU A 1 139 ? 200.061 194.167 105.774 1.00 28.22  ? 171  LEU B C   1 
ATOM   811   O O   . LEU A 1 139 ? 200.031 193.018 105.338 1.00 28.22  ? 171  LEU B O   1 
ATOM   812   C CB  . LEU A 1 139 ? 198.035 194.398 107.210 1.00 40.11  ? 171  LEU B CB  1 
ATOM   813   C CG  . LEU A 1 139 ? 197.416 194.619 108.630 1.00 40.11  ? 171  LEU B CG  1 
ATOM   814   C CD1 . LEU A 1 139 ? 195.936 194.668 108.496 1.00 40.11  ? 171  LEU B CD1 1 
ATOM   815   C CD2 . LEU A 1 139 ? 197.826 193.514 109.603 1.00 40.11  ? 171  LEU B CD2 1 
ATOM   816   N N   . PHE A 1 140 ? 200.540 195.181 105.080 1.00 52.02  ? 172  PHE B N   1 
ATOM   817   C CA  . PHE A 1 140 ? 201.076 194.995 103.763 1.00 52.02  ? 172  PHE B CA  1 
ATOM   818   C C   . PHE A 1 140 ? 202.556 195.293 103.808 1.00 52.02  ? 172  PHE B C   1 
ATOM   819   O O   . PHE A 1 140 ? 203.200 195.462 102.772 1.00 52.02  ? 172  PHE B O   1 
ATOM   820   C CB  . PHE A 1 140 ? 200.360 195.905 102.805 1.00 70.35  ? 172  PHE B CB  1 
ATOM   821   C CG  . PHE A 1 140 ? 198.920 195.665 102.856 1.00 70.35  ? 172  PHE B CG  1 
ATOM   822   C CD1 . PHE A 1 140 ? 198.395 194.458 102.507 1.00 70.35  ? 172  PHE B CD1 1 
ATOM   823   C CD2 . PHE A 1 140 ? 198.075 196.635 103.308 1.00 70.35  ? 172  PHE B CD2 1 
ATOM   824   C CE1 . PHE A 1 140 ? 197.052 194.230 102.578 1.00 70.35  ? 172  PHE B CE1 1 
ATOM   825   C CE2 . PHE A 1 140 ? 196.737 196.404 103.372 1.00 70.35  ? 172  PHE B CE2 1 
ATOM   826   C CZ  . PHE A 1 140 ? 196.232 195.209 103.001 1.00 70.35  ? 172  PHE B CZ  1 
ATOM   827   N N   . LYS A 1 141 ? 203.090 195.360 105.028 1.00 27.79  ? 173  LYS B N   1 
ATOM   828   C CA  . LYS A 1 141 ? 204.462 195.729 105.294 1.00 27.79  ? 173  LYS B CA  1 
ATOM   829   C C   . LYS A 1 141 ? 204.845 197.099 104.773 1.00 27.79  ? 173  LYS B C   1 
ATOM   830   O O   . LYS A 1 141 ? 205.899 197.247 104.161 1.00 27.79  ? 173  LYS B O   1 
ATOM   831   C CB  . LYS A 1 141 ? 205.446 194.716 104.722 1.00 39.75  ? 173  LYS B CB  1 
ATOM   832   C CG  . LYS A 1 141 ? 205.370 193.341 105.308 1.00 39.75  ? 173  LYS B CG  1 
ATOM   833   C CD  . LYS A 1 141 ? 206.428 192.473 104.658 1.00 39.75  ? 173  LYS B CD  1 
ATOM   834   C CE  . LYS A 1 141 ? 206.536 191.088 105.265 1.00 39.75  ? 173  LYS B CE  1 
ATOM   835   N NZ  . LYS A 1 141 ? 207.528 190.245 104.514 1.00 39.75  ? 173  LYS B NZ  1 
ATOM   836   N N   . ILE A 1 142 ? 203.997 198.096 104.983 1.00 19.83  ? 174  ILE B N   1 
ATOM   837   C CA  . ILE A 1 142 ? 204.288 199.443 104.540 1.00 19.83  ? 174  ILE B CA  1 
ATOM   838   C C   . ILE A 1 142 ? 204.536 200.423 105.706 1.00 19.83  ? 174  ILE B C   1 
ATOM   839   O O   . ILE A 1 142 ? 203.645 200.616 106.529 1.00 19.83  ? 174  ILE B O   1 
ATOM   840   C CB  . ILE A 1 142 ? 203.129 199.938 103.674 1.00 28.19  ? 174  ILE B CB  1 
ATOM   841   C CG1 . ILE A 1 142 ? 202.890 198.933 102.505 1.00 28.19  ? 174  ILE B CG1 1 
ATOM   842   C CG2 . ILE A 1 142 ? 203.376 201.361 103.194 1.00 28.19  ? 174  ILE B CG2 1 
ATOM   843   C CD1 . ILE A 1 142 ? 204.046 198.703 101.534 1.00 28.19  ? 174  ILE B CD1 1 
ATOM   844   N N   . PRO A 1 143 ? 205.768 200.966 105.819 1.00 16.36  ? 175  PRO B N   1 
ATOM   845   C CA  . PRO A 1 143 ? 206.166 201.882 106.872 1.00 16.36  ? 175  PRO B CA  1 
ATOM   846   C C   . PRO A 1 143 ? 205.405 203.185 106.863 1.00 16.36  ? 175  PRO B C   1 
ATOM   847   O O   . PRO A 1 143 ? 205.085 203.717 105.802 1.00 16.36  ? 175  PRO B O   1 
ATOM   848   C CB  . PRO A 1 143 ? 207.632 202.213 106.659 1.00 27.96  ? 175  PRO B CB  1 
ATOM   849   C CG  . PRO A 1 143 ? 208.143 201.050 105.842 1.00 27.96  ? 175  PRO B CG  1 
ATOM   850   C CD  . PRO A 1 143 ? 206.934 200.641 105.018 1.00 27.96  ? 175  PRO B CD  1 
ATOM   851   N N   . GLN A 1 144 ? 205.144 203.705 108.055 1.00 22.63  ? 176  GLN B N   1 
ATOM   852   C CA  . GLN A 1 144 ? 204.346 204.903 108.269 1.00 22.63  ? 176  GLN B CA  1 
ATOM   853   C C   . GLN A 1 144 ? 204.997 205.791 109.318 1.00 22.63  ? 176  GLN B C   1 
ATOM   854   O O   . GLN A 1 144 ? 205.391 205.312 110.379 1.00 22.63  ? 176  GLN B O   1 
ATOM   855   C CB  . GLN A 1 144 ? 202.934 204.478 108.667 1.00 30.76  ? 176  GLN B CB  1 
ATOM   856   C CG  . GLN A 1 144 ? 202.057 205.650 109.099 1.00 30.76  ? 176  GLN B CG  1 
ATOM   857   C CD  . GLN A 1 144 ? 200.647 205.207 109.411 1.00 30.76  ? 176  GLN B CD  1 
ATOM   858   O OE1 . GLN A 1 144 ? 200.241 204.111 109.126 1.00 30.76  ? 176  GLN B OE1 1 
ATOM   859   N NE2 . GLN A 1 144 ? 199.831 206.034 110.007 1.00 30.76  ? 176  GLN B NE2 1 
ATOM   860   N N   . ILE A 1 145 ? 205.065 207.088 109.035 1.00 24.28  ? 177  ILE B N   1 
ATOM   861   C CA  . ILE A 1 145 ? 205.736 208.054 109.886 1.00 24.28  ? 177  ILE B CA  1 
ATOM   862   C C   . ILE A 1 145 ? 204.822 209.233 110.195 1.00 24.28  ? 177  ILE B C   1 
ATOM   863   O O   . ILE A 1 145 ? 204.085 209.728 109.340 1.00 24.28  ? 177  ILE B O   1 
ATOM   864   C CB  . ILE A 1 145 ? 207.082 208.447 109.277 1.00 34.51  ? 177  ILE B CB  1 
ATOM   865   C CG1 . ILE A 1 145 ? 207.981 207.203 109.177 1.00 34.51  ? 177  ILE B CG1 1 
ATOM   866   C CG2 . ILE A 1 145 ? 207.746 209.516 110.141 1.00 34.51  ? 177  ILE B CG2 1 
ATOM   867   C CD1 . ILE A 1 145 ? 209.369 207.498 108.619 1.00 34.51  ? 177  ILE B CD1 1 
ATOM   868   N N   . SER A 1 146 ? 204.849 209.674 111.446 1.00 52.02  ? 178  SER B N   1 
ATOM   869   C CA  . SER A 1 146 ? 203.998 210.743 111.937 1.00 52.02  ? 178  SER B CA  1 
ATOM   870   C C   . SER A 1 146 ? 204.797 212.006 112.276 1.00 52.02  ? 178  SER B C   1 
ATOM   871   O O   . SER A 1 146 ? 205.545 212.011 113.251 1.00 52.02  ? 178  SER B O   1 
ATOM   872   C CB  . SER A 1 146 ? 203.190 210.229 113.128 1.00 69.29  ? 178  SER B CB  1 
ATOM   873   O OG  . SER A 1 146 ? 202.488 211.284 113.758 1.00 69.29  ? 178  SER B OG  1 
ATOM   874   N N   . TYR A 1 147 ? 204.544 213.103 111.544 1.00 31.80  ? 179  TYR B N   1 
ATOM   875   C CA  . TYR A 1 147 ? 204.862 214.477 111.944 1.00 31.80  ? 179  TYR B CA  1 
ATOM   876   C C   . TYR A 1 147 ? 203.998 215.000 113.109 1.00 31.80  ? 179  TYR B C   1 
ATOM   877   O O   . TYR A 1 147 ? 204.115 216.167 113.466 1.00 31.80  ? 179  TYR B O   1 
ATOM   878   C CB  . TYR A 1 147 ? 204.799 215.426 110.727 1.00 42.68  ? 179  TYR B CB  1 
ATOM   879   C CG  . TYR A 1 147 ? 203.439 215.610 110.081 1.00 42.68  ? 179  TYR B CG  1 
ATOM   880   C CD1 . TYR A 1 147 ? 202.379 216.209 110.773 1.00 42.68  ? 179  TYR B CD1 1 
ATOM   881   C CD2 . TYR A 1 147 ? 203.233 215.175 108.769 1.00 42.68  ? 179  TYR B CD2 1 
ATOM   882   C CE1 . TYR A 1 147 ? 201.090 216.241 110.216 1.00 42.68  ? 179  TYR B CE1 1 
ATOM   883   C CE2 . TYR A 1 147 ? 201.945 215.192 108.213 1.00 42.68  ? 179  TYR B CE2 1 
ATOM   884   C CZ  . TYR A 1 147 ? 200.866 215.726 108.935 1.00 42.68  ? 179  TYR B CZ  1 
ATOM   885   O OH  . TYR A 1 147 ? 199.600 215.668 108.454 1.00 42.68  ? 179  TYR B OH  1 
ATOM   886   N N   . ALA A 1 148 ? 203.092 214.204 113.680 1.00 23.17  ? 180  ALA B N   1 
ATOM   887   C CA  . ALA A 1 148 ? 202.021 214.700 114.542 1.00 23.17  ? 180  ALA B CA  1 
ATOM   888   C C   . ALA A 1 148 ? 201.723 213.829 115.772 1.00 23.17  ? 180  ALA B C   1 
ATOM   889   O O   . ALA A 1 148 ? 202.310 214.072 116.816 1.00 23.17  ? 180  ALA B O   1 
ATOM   890   C CB  . ALA A 1 148 ? 200.799 214.959 113.675 1.00 31.30  ? 180  ALA B CB  1 
ATOM   891   N N   . SER A 1 149 ? 200.772 212.889 115.706 1.00 21.68  ? 181  SER B N   1 
ATOM   892   C CA  . SER A 1 149 ? 200.168 212.368 116.933 1.00 21.68  ? 181  SER B CA  1 
ATOM   893   C C   . SER A 1 149 ? 201.197 211.777 117.902 1.00 21.68  ? 181  SER B C   1 
ATOM   894   O O   . SER A 1 149 ? 201.919 210.842 117.572 1.00 21.68  ? 181  SER B O   1 
ATOM   895   C CB  . SER A 1 149 ? 199.063 211.371 116.619 1.00 28.88  ? 181  SER B CB  1 
ATOM   896   O OG  . SER A 1 149 ? 198.271 211.166 117.767 1.00 28.88  ? 181  SER B OG  1 
ATOM   897   N N   . THR A 1 150 ? 201.278 212.354 119.102 1.00 20.52  ? 182  THR B N   1 
ATOM   898   C CA  . THR A 1 150 ? 202.203 211.996 120.196 1.00 20.52  ? 182  THR B CA  1 
ATOM   899   C C   . THR A 1 150 ? 201.645 210.934 121.144 1.00 20.52  ? 182  THR B C   1 
ATOM   900   O O   . THR A 1 150 ? 202.285 210.617 122.145 1.00 20.52  ? 182  THR B O   1 
ATOM   901   C CB  . THR A 1 150 ? 202.515 213.247 121.030 1.00 28.09  ? 182  THR B CB  1 
ATOM   902   O OG1 . THR A 1 150 ? 201.323 213.878 121.404 1.00 28.09  ? 182  THR B OG1 1 
ATOM   903   C CG2 . THR A 1 150 ? 203.319 214.268 120.252 1.00 28.09  ? 182  THR B CG2 1 
ATOM   904   N N   . ALA A 1 151 ? 200.445 210.420 120.879 1.00 25.00  ? 183  ALA B N   1 
ATOM   905   C CA  . ALA A 1 151 ? 199.710 209.663 121.872 1.00 25.00  ? 183  ALA B CA  1 
ATOM   906   C C   . ALA A 1 151 ? 200.483 208.409 122.316 1.00 25.00  ? 183  ALA B C   1 
ATOM   907   O O   . ALA A 1 151 ? 201.196 207.818 121.508 1.00 25.00  ? 183  ALA B O   1 
ATOM   908   C CB  . ALA A 1 151 ? 198.332 209.341 121.303 1.00 33.77  ? 183  ALA B CB  1 
ATOM   909   N N   . PRO A 1 152 ? 200.349 207.966 123.571 1.00 27.38  ? 184  PRO B N   1 
ATOM   910   C CA  . PRO A 1 152 ? 201.070 206.816 124.100 1.00 27.38  ? 184  PRO B CA  1 
ATOM   911   C C   . PRO A 1 152 ? 200.827 205.537 123.309 1.00 27.38  ? 184  PRO B C   1 
ATOM   912   O O   . PRO A 1 152 ? 201.762 204.774 123.097 1.00 27.38  ? 184  PRO B O   1 
ATOM   913   C CB  . PRO A 1 152 ? 200.561 206.634 125.529 1.00 46.79  ? 184  PRO B CB  1 
ATOM   914   C CG  . PRO A 1 152 ? 199.931 207.969 125.889 1.00 46.79  ? 184  PRO B CG  1 
ATOM   915   C CD  . PRO A 1 152 ? 199.411 208.451 124.551 1.00 46.79  ? 184  PRO B CD  1 
ATOM   916   N N   . ASP A 1 153 ? 199.595 205.316 122.847 1.00 29.06  ? 185  ASP B N   1 
ATOM   917   C CA  . ASP A 1 153 ? 199.142 204.054 122.249 1.00 29.06  ? 185  ASP B CA  1 
ATOM   918   C C   . ASP A 1 153 ? 200.075 203.517 121.169 1.00 29.06  ? 185  ASP B C   1 
ATOM   919   O O   . ASP A 1 153 ? 200.365 202.328 121.110 1.00 29.06  ? 185  ASP B O   1 
ATOM   920   C CB  . ASP A 1 153 ? 197.776 204.266 121.595 1.00 37.00  ? 185  ASP B CB  1 
ATOM   921   C CG  . ASP A 1 153 ? 196.726 204.759 122.572 1.00 37.00  ? 185  ASP B CG  1 
ATOM   922   O OD1 . ASP A 1 153 ? 196.274 203.933 123.385 1.00 37.00  ? 185  ASP B OD1 1 
ATOM   923   O OD2 . ASP A 1 153 ? 196.346 205.947 122.507 1.00 37.00  ? 185  ASP B OD2 1 
ATOM   924   N N   . LEU A 1 154 ? 200.562 204.410 120.313 1.00 24.09  ? 186  LEU B N   1 
ATOM   925   C CA  . LEU A 1 154 ? 201.323 204.046 119.135 1.00 24.09  ? 186  LEU B CA  1 
ATOM   926   C C   . LEU A 1 154 ? 202.707 203.477 119.482 1.00 24.09  ? 186  LEU B C   1 
ATOM   927   O O   . LEU A 1 154 ? 203.375 202.924 118.619 1.00 24.09  ? 186  LEU B O   1 
ATOM   928   C CB  . LEU A 1 154 ? 201.352 205.237 118.164 1.00 34.24  ? 186  LEU B CB  1 
ATOM   929   C CG  . LEU A 1 154 ? 199.945 205.675 117.701 1.00 34.24  ? 186  LEU B CG  1 
ATOM   930   C CD1 . LEU A 1 154 ? 199.379 206.813 118.546 1.00 34.24  ? 186  LEU B CD1 1 
ATOM   931   C CD2 . LEU A 1 154 ? 199.953 206.190 116.266 1.00 34.24  ? 186  LEU B CD2 1 
ATOM   932   N N   . SER A 1 155 ? 203.159 203.594 120.730 1.00 32.23  ? 187  SER B N   1 
ATOM   933   C CA  . SER A 1 155 ? 204.392 202.957 121.192 1.00 32.23  ? 187  SER B CA  1 
ATOM   934   C C   . SER A 1 155 ? 204.231 201.466 121.515 1.00 32.23  ? 187  SER B C   1 
ATOM   935   O O   . SER A 1 155 ? 205.224 200.799 121.794 1.00 32.23  ? 187  SER B O   1 
ATOM   936   C CB  . SER A 1 155 ? 204.963 203.710 122.393 1.00 42.93  ? 187  SER B CB  1 
ATOM   937   O OG  . SER A 1 155 ? 204.162 203.511 123.535 1.00 42.93  ? 187  SER B OG  1 
ATOM   938   N N   . ASP A 1 156 ? 203.020 200.900 121.452 1.00 35.22  ? 188  ASP B N   1 
ATOM   939   C CA  . ASP A 1 156 ? 202.862 199.446 121.392 1.00 35.22  ? 188  ASP B CA  1 
ATOM   940   C C   . ASP A 1 156 ? 203.304 198.905 120.020 1.00 35.22  ? 188  ASP B C   1 
ATOM   941   O O   . ASP A 1 156 ? 202.565 198.885 119.029 1.00 35.22  ? 188  ASP B O   1 
ATOM   942   C CB  . ASP A 1 156 ? 201.433 199.019 121.731 1.00 44.85  ? 188  ASP B CB  1 
ATOM   943   C CG  . ASP A 1 156 ? 201.307 197.493 121.821 1.00 44.85  ? 188  ASP B CG  1 
ATOM   944   O OD1 . ASP A 1 156 ? 202.320 196.779 121.630 1.00 44.85  ? 188  ASP B OD1 1 
ATOM   945   O OD2 . ASP A 1 156 ? 200.200 197.005 122.134 1.00 44.85  ? 188  ASP B OD2 1 
ATOM   946   N N   . ASN A 1 157 ? 204.527 198.389 119.963 1.00 35.06  ? 189  ASN B N   1 
ATOM   947   C CA  . ASN A 1 157 ? 205.099 197.871 118.733 1.00 35.06  ? 189  ASN B CA  1 
ATOM   948   C C   . ASN A 1 157 ? 204.472 196.572 118.308 1.00 35.06  ? 189  ASN B C   1 
ATOM   949   O O   . ASN A 1 157 ? 204.807 196.037 117.253 1.00 35.06  ? 189  ASN B O   1 
ATOM   950   C CB  . ASN A 1 157 ? 206.569 197.660 118.928 1.00 46.64  ? 189  ASN B CB  1 
ATOM   951   C CG  . ASN A 1 157 ? 207.247 198.921 119.180 1.00 46.64  ? 189  ASN B CG  1 
ATOM   952   O OD1 . ASN A 1 157 ? 206.828 199.991 118.735 1.00 46.64  ? 189  ASN B OD1 1 
ATOM   953   N ND2 . ASN A 1 157 ? 208.284 198.816 119.943 1.00 46.64  ? 189  ASN B ND2 1 
ATOM   954   N N   . SER A 1 158 ? 203.583 196.021 119.134 1.00 35.40  ? 190  SER B N   1 
ATOM   955   C CA  . SER A 1 158 ? 202.937 194.774 118.766 1.00 35.40  ? 190  SER B CA  1 
ATOM   956   C C   . SER A 1 158 ? 201.730 195.106 117.912 1.00 35.40  ? 190  SER B C   1 
ATOM   957   O O   . SER A 1 158 ? 201.086 194.223 117.335 1.00 35.40  ? 190  SER B O   1 
ATOM   958   C CB  . SER A 1 158 ? 202.492 193.989 119.980 1.00 47.15  ? 190  SER B CB  1 
ATOM   959   O OG  . SER A 1 158 ? 201.387 194.586 120.595 1.00 47.15  ? 190  SER B OG  1 
ATOM   960   N N   . ARG A 1 159 ? 201.400 196.392 117.857 1.00 32.30  ? 191  ARG B N   1 
ATOM   961   C CA  . ARG A 1 159 ? 200.259 196.874 117.128 1.00 32.30  ? 191  ARG B CA  1 
ATOM   962   C C   . ARG A 1 159 ? 200.704 197.798 116.025 1.00 32.30  ? 191  ARG B C   1 
ATOM   963   O O   . ARG A 1 159 ? 200.111 197.828 114.957 1.00 32.30  ? 191  ARG B O   1 
ATOM   964   C CB  . ARG A 1 159 ? 199.369 197.638 118.059 1.00 45.36  ? 191  ARG B CB  1 
ATOM   965   C CG  . ARG A 1 159 ? 198.741 196.842 119.106 1.00 45.36  ? 191  ARG B CG  1 
ATOM   966   C CD  . ARG A 1 159 ? 197.998 197.692 120.024 1.00 45.36  ? 191  ARG B CD  1 
ATOM   967   N NE  . ARG A 1 159 ? 197.541 196.922 121.120 1.00 45.36  ? 191  ARG B NE  1 
ATOM   968   C CZ  . ARG A 1 159 ? 196.348 196.274 121.212 1.00 45.36  ? 191  ARG B CZ  1 
ATOM   969   N NH1 . ARG A 1 159 ? 196.110 195.548 122.282 1.00 45.36  ? 191  ARG B NH1 1 
ATOM   970   N NH2 . ARG A 1 159 ? 195.448 196.374 120.244 1.00 45.36  ? 191  ARG B NH2 1 
ATOM   971   N N   . TYR A 1 160 ? 201.848 198.439 116.193 1.00 24.28  ? 192  TYR B N   1 
ATOM   972   C CA  . TYR A 1 160 ? 202.343 199.368 115.205 1.00 24.28  ? 192  TYR B CA  1 
ATOM   973   C C   . TYR A 1 160 ? 203.755 199.000 114.786 1.00 24.28  ? 192  TYR B C   1 
ATOM   974   O O   . TYR A 1 160 ? 204.656 199.829 114.791 1.00 24.28  ? 192  TYR B O   1 
ATOM   975   C CB  . TYR A 1 160 ? 202.103 200.764 115.764 1.00 32.59  ? 192  TYR B CB  1 
ATOM   976   C CG  . TYR A 1 160 ? 200.673 200.901 116.221 1.00 32.59  ? 192  TYR B CG  1 
ATOM   977   C CD1 . TYR A 1 160 ? 199.639 200.805 115.281 1.00 32.59  ? 192  TYR B CD1 1 
ATOM   978   C CD2 . TYR A 1 160 ? 200.372 200.952 117.588 1.00 32.59  ? 192  TYR B CD2 1 
ATOM   979   C CE1 . TYR A 1 160 ? 198.306 200.799 115.704 1.00 32.59  ? 192  TYR B CE1 1 
ATOM   980   C CE2 . TYR A 1 160 ? 199.035 200.935 118.016 1.00 32.59  ? 192  TYR B CE2 1 
ATOM   981   C CZ  . TYR A 1 160 ? 197.999 200.839 117.073 1.00 32.59  ? 192  TYR B CZ  1 
ATOM   982   O OH  . TYR A 1 160 ? 196.709 200.741 117.472 1.00 32.59  ? 192  TYR B OH  1 
ATOM   983   N N   . ASP A 1 161 ? 203.961 197.738 114.409 1.00 23.01  ? 193  ASP B N   1 
ATOM   984   C CA  . ASP A 1 161 ? 205.289 197.218 114.061 1.00 23.01  ? 193  ASP B CA  1 
ATOM   985   C C   . ASP A 1 161 ? 205.946 197.982 112.900 1.00 23.01  ? 193  ASP B C   1 
ATOM   986   O O   . ASP A 1 161 ? 207.170 198.039 112.824 1.00 23.01  ? 193  ASP B O   1 
ATOM   987   C CB  . ASP A 1 161 ? 205.295 195.695 113.800 1.00 29.30  ? 193  ASP B CB  1 
ATOM   988   C CG  . ASP A 1 161 ? 204.167 195.093 112.949 1.00 29.30  ? 193  ASP B CG  1 
ATOM   989   O OD1 . ASP A 1 161 ? 203.001 195.522 113.063 1.00 29.30  ? 193  ASP B OD1 1 
ATOM   990   O OD2 . ASP A 1 161 ? 204.446 194.131 112.200 1.00 29.30  ? 193  ASP B OD2 1 
ATOM   991   N N   . PHE A 1 162 ? 205.165 198.634 112.039 1.00 19.89  ? 194  PHE B N   1 
ATOM   992   C CA  . PHE A 1 162 ? 205.679 199.417 110.922 1.00 19.89  ? 194  PHE B CA  1 
ATOM   993   C C   . PHE A 1 162 ? 205.813 200.929 111.185 1.00 19.89  ? 194  PHE B C   1 
ATOM   994   O O   . PHE A 1 162 ? 205.981 201.710 110.251 1.00 19.89  ? 194  PHE B O   1 
ATOM   995   C CB  . PHE A 1 162 ? 204.887 199.031 109.663 1.00 26.90  ? 194  PHE B CB  1 
ATOM   996   C CG  . PHE A 1 162 ? 205.418 197.764 109.019 1.00 26.90  ? 194  PHE B CG  1 
ATOM   997   C CD1 . PHE A 1 162 ? 205.182 196.510 109.603 1.00 26.90  ? 194  PHE B CD1 1 
ATOM   998   C CD2 . PHE A 1 162 ? 206.242 197.847 107.880 1.00 26.90  ? 194  PHE B CD2 1 
ATOM   999   C CE1 . PHE A 1 162 ? 205.790 195.358 109.073 1.00 26.90  ? 194  PHE B CE1 1 
ATOM   1000  C CE2 . PHE A 1 162 ? 206.853 196.697 107.358 1.00 26.90  ? 194  PHE B CE2 1 
ATOM   1001  C CZ  . PHE A 1 162 ? 206.645 195.452 107.965 1.00 26.90  ? 194  PHE B CZ  1 
ATOM   1002  N N   . PHE A 1 163 ? 205.749 201.393 112.428 1.00 16.77  ? 195  PHE B N   1 
ATOM   1003  C CA  . PHE A 1 163 ? 205.444 202.800 112.700 1.00 16.77  ? 195  PHE B CA  1 
ATOM   1004  C C   . PHE A 1 163 ? 206.528 203.548 113.447 1.00 16.77  ? 195  PHE B C   1 
ATOM   1005  O O   . PHE A 1 163 ? 207.201 202.966 114.289 1.00 16.77  ? 195  PHE B O   1 
ATOM   1006  C CB  . PHE A 1 163 ? 204.175 202.846 113.526 1.00 22.68  ? 195  PHE B CB  1 
ATOM   1007  C CG  . PHE A 1 163 ? 203.585 204.214 113.713 1.00 22.68  ? 195  PHE B CG  1 
ATOM   1008  C CD1 . PHE A 1 163 ? 202.756 204.743 112.722 1.00 22.68  ? 195  PHE B CD1 1 
ATOM   1009  C CD2 . PHE A 1 163 ? 203.761 204.904 114.915 1.00 22.68  ? 195  PHE B CD2 1 
ATOM   1010  C CE1 . PHE A 1 163 ? 202.099 205.957 112.933 1.00 22.68  ? 195  PHE B CE1 1 
ATOM   1011  C CE2 . PHE A 1 163 ? 203.105 206.127 115.118 1.00 22.68  ? 195  PHE B CE2 1 
ATOM   1012  C CZ  . PHE A 1 163 ? 202.282 206.658 114.123 1.00 22.68  ? 195  PHE B CZ  1 
ATOM   1013  N N   . SER A 1 164 ? 206.635 204.853 113.213 1.00 18.21  ? 196  SER B N   1 
ATOM   1014  C CA  . SER A 1 164 ? 207.287 205.774 114.148 1.00 18.21  ? 196  SER B CA  1 
ATOM   1015  C C   . SER A 1 164 ? 206.575 207.122 114.164 1.00 18.21  ? 196  SER B C   1 
ATOM   1016  O O   . SER A 1 164 ? 205.951 207.546 113.189 1.00 18.21  ? 196  SER B O   1 
ATOM   1017  C CB  . SER A 1 164 ? 208.781 205.971 113.840 1.00 24.26  ? 196  SER B CB  1 
ATOM   1018  O OG  . SER A 1 164 ? 209.001 206.951 112.852 1.00 24.26  ? 196  SER B OG  1 
ATOM   1019  N N   . ARG A 1 165 ? 206.706 207.853 115.266 1.00 16.57  ? 197  ARG B N   1 
ATOM   1020  C CA  . ARG A 1 165 ? 206.476 209.297 115.255 1.00 16.57  ? 197  ARG B CA  1 
ATOM   1021  C C   . ARG A 1 165 ? 207.797 209.966 114.853 1.00 16.57  ? 197  ARG B C   1 
ATOM   1022  O O   . ARG A 1 165 ? 208.768 209.287 114.508 1.00 16.57  ? 197  ARG B O   1 
ATOM   1023  C CB  . ARG A 1 165 ? 205.942 209.726 116.635 1.00 23.27  ? 197  ARG B CB  1 
ATOM   1024  C CG  . ARG A 1 165 ? 204.676 208.956 117.039 1.00 23.27  ? 197  ARG B CG  1 
ATOM   1025  C CD  . ARG A 1 165 ? 204.374 209.081 118.535 1.00 23.27  ? 197  ARG B CD  1 
ATOM   1026  N NE  . ARG A 1 165 ? 205.357 208.357 119.356 1.00 23.27  ? 197  ARG B NE  1 
ATOM   1027  C CZ  . ARG A 1 165 ? 205.602 207.066 119.398 1.00 23.27  ? 197  ARG B CZ  1 
ATOM   1028  N NH1 . ARG A 1 165 ? 206.614 206.633 120.064 1.00 23.27  ? 197  ARG B NH1 1 
ATOM   1029  N NH2 . ARG A 1 165 ? 204.875 206.180 118.791 1.00 23.27  ? 197  ARG B NH2 1 
ATOM   1030  N N   . VAL A 1 166 ? 207.841 211.290 114.896 1.00 14.14  ? 198  VAL B N   1 
ATOM   1031  C CA  . VAL A 1 166 ? 209.075 212.077 114.771 1.00 14.14  ? 198  VAL B CA  1 
ATOM   1032  C C   . VAL A 1 166 ? 209.210 213.091 115.896 1.00 14.14  ? 198  VAL B C   1 
ATOM   1033  O O   . VAL A 1 166 ? 209.949 214.059 115.808 1.00 14.14  ? 198  VAL B O   1 
ATOM   1034  C CB  . VAL A 1 166 ? 209.180 212.736 113.394 1.00 19.91  ? 198  VAL B CB  1 
ATOM   1035  C CG1 . VAL A 1 166 ? 208.894 211.740 112.275 1.00 19.91  ? 198  VAL B CG1 1 
ATOM   1036  C CG2 . VAL A 1 166 ? 208.242 213.930 113.241 1.00 19.91  ? 198  VAL B CG2 1 
ATOM   1037  N N   . VAL A 1 167 ? 208.461 212.869 116.967 1.00 15.22  ? 199  VAL B N   1 
ATOM   1038  C CA  . VAL A 1 167 ? 208.255 213.785 118.080 1.00 15.22  ? 199  VAL B CA  1 
ATOM   1039  C C   . VAL A 1 167 ? 208.201 212.968 119.363 1.00 15.22  ? 199  VAL B C   1 
ATOM   1040  O O   . VAL A 1 167 ? 207.962 211.765 119.299 1.00 15.22  ? 199  VAL B O   1 
ATOM   1041  C CB  . VAL A 1 167 ? 206.964 214.600 117.894 1.00 21.43  ? 199  VAL B CB  1 
ATOM   1042  C CG1 . VAL A 1 167 ? 207.090 215.488 116.660 1.00 21.43  ? 199  VAL B CG1 1 
ATOM   1043  C CG2 . VAL A 1 167 ? 205.695 213.761 117.739 1.00 21.43  ? 199  VAL B CG2 1 
ATOM   1044  N N   . PRO A 1 168 ? 208.454 213.562 120.531 1.00 16.91  ? 200  PRO B N   1 
ATOM   1045  C CA  . PRO A 1 168 ? 208.274 212.875 121.794 1.00 16.91  ? 200  PRO B CA  1 
ATOM   1046  C C   . PRO A 1 168 ? 206.800 212.665 122.090 1.00 16.91  ? 200  PRO B C   1 
ATOM   1047  O O   . PRO A 1 168 ? 205.955 213.504 121.788 1.00 16.91  ? 200  PRO B O   1 
ATOM   1048  C CB  . PRO A 1 168 ? 208.919 213.766 122.843 1.00 28.90  ? 200  PRO B CB  1 
ATOM   1049  C CG  . PRO A 1 168 ? 208.842 215.159 122.240 1.00 28.90  ? 200  PRO B CG  1 
ATOM   1050  C CD  . PRO A 1 168 ? 208.964 214.898 120.742 1.00 28.90  ? 200  PRO B CD  1 
ATOM   1051  N N   . SER A 1 169 ? 206.486 211.548 122.715 1.00 18.60  ? 201  SER B N   1 
ATOM   1052  C CA  . SER A 1 169 ? 205.132 211.222 123.103 1.00 18.60  ? 201  SER B CA  1 
ATOM   1053  C C   . SER A 1 169 ? 204.620 212.103 124.228 1.00 18.60  ? 201  SER B C   1 
ATOM   1054  O O   . SER A 1 169 ? 205.364 212.736 124.981 1.00 18.60  ? 201  SER B O   1 
ATOM   1055  C CB  . SER A 1 169 ? 205.051 209.769 123.561 1.00 24.77  ? 201  SER B CB  1 
ATOM   1056  O OG  . SER A 1 169 ? 205.926 209.565 124.647 1.00 24.77  ? 201  SER B OG  1 
ATOM   1057  N N   . ASP A 1 170 ? 203.320 212.006 124.463 1.00 23.34  ? 202  ASP B N   1 
ATOM   1058  C CA  . ASP A 1 170 ? 202.718 212.491 125.695 1.00 23.34  ? 202  ASP B CA  1 
ATOM   1059  C C   . ASP A 1 170 ? 203.344 211.925 126.955 1.00 23.34  ? 202  ASP B C   1 
ATOM   1060  O O   . ASP A 1 170 ? 203.268 212.577 127.984 1.00 23.34  ? 202  ASP B O   1 
ATOM   1061  C CB  . ASP A 1 170 ? 201.226 212.215 125.686 1.00 29.72  ? 202  ASP B CB  1 
ATOM   1062  C CG  . ASP A 1 170 ? 200.617 213.061 124.583 1.00 29.72  ? 202  ASP B CG  1 
ATOM   1063  O OD1 . ASP A 1 170 ? 200.336 214.243 124.856 1.00 29.72  ? 202  ASP B OD1 1 
ATOM   1064  O OD2 . ASP A 1 170 ? 200.532 212.564 123.443 1.00 29.72  ? 202  ASP B OD2 1 
ATOM   1065  N N   . THR A 1 171 ? 204.033 210.787 126.916 1.00 23.52  ? 203  THR B N   1 
ATOM   1066  C CA  . THR A 1 171 ? 204.739 210.326 128.118 1.00 23.52  ? 203  THR B CA  1 
ATOM   1067  C C   . THR A 1 171 ? 205.774 211.350 128.578 1.00 23.52  ? 203  THR B C   1 
ATOM   1068  O O   . THR A 1 171 ? 205.966 211.563 129.769 1.00 23.52  ? 203  THR B O   1 
ATOM   1069  C CB  . THR A 1 171 ? 205.353 208.929 127.913 1.00 32.20  ? 203  THR B CB  1 
ATOM   1070  O OG1 . THR A 1 171 ? 205.826 208.472 129.158 1.00 32.20  ? 203  THR B OG1 1 
ATOM   1071  C CG2 . THR A 1 171 ? 206.543 208.831 126.955 1.00 32.20  ? 203  THR B CG2 1 
ATOM   1072  N N   . TYR A 1 172 ? 206.396 212.062 127.644 1.00 23.77  ? 204  TYR B N   1 
ATOM   1073  C CA  . TYR A 1 172 ? 207.245 213.188 127.977 1.00 23.77  ? 204  TYR B CA  1 
ATOM   1074  C C   . TYR A 1 172 ? 206.402 214.419 128.276 1.00 23.77  ? 204  TYR B C   1 
ATOM   1075  O O   . TYR A 1 172 ? 206.555 215.007 129.336 1.00 23.77  ? 204  TYR B O   1 
ATOM   1076  C CB  . TYR A 1 172 ? 208.235 213.436 126.843 1.00 31.91  ? 204  TYR B CB  1 
ATOM   1077  C CG  . TYR A 1 172 ? 209.267 212.336 126.683 1.00 31.91  ? 204  TYR B CG  1 
ATOM   1078  C CD1 . TYR A 1 172 ? 208.978 211.202 125.908 1.00 31.91  ? 204  TYR B CD1 1 
ATOM   1079  C CD2 . TYR A 1 172 ? 210.513 212.439 127.324 1.00 31.91  ? 204  TYR B CD2 1 
ATOM   1080  C CE1 . TYR A 1 172 ? 209.915 210.159 125.800 1.00 31.91  ? 204  TYR B CE1 1 
ATOM   1081  C CE2 . TYR A 1 172 ? 211.471 211.425 127.177 1.00 31.91  ? 204  TYR B CE2 1 
ATOM   1082  C CZ  . TYR A 1 172 ? 211.171 210.274 126.429 1.00 31.91  ? 204  TYR B CZ  1 
ATOM   1083  O OH  . TYR A 1 172 ? 212.088 209.280 126.321 1.00 31.91  ? 204  TYR B OH  1 
ATOM   1084  N N   . GLN A 1 173 ? 205.494 214.837 127.388 1.00 24.97  ? 205  GLN B N   1 
ATOM   1085  C CA  . GLN A 1 173 ? 204.808 216.119 127.596 1.00 24.97  ? 205  GLN B CA  1 
ATOM   1086  C C   . GLN A 1 173 ? 203.934 216.143 128.847 1.00 24.97  ? 205  GLN B C   1 
ATOM   1087  O O   . GLN A 1 173 ? 203.925 217.128 129.575 1.00 24.97  ? 205  GLN B O   1 
ATOM   1088  C CB  . GLN A 1 173 ? 203.971 216.524 126.395 1.00 33.94  ? 205  GLN B CB  1 
ATOM   1089  C CG  . GLN A 1 173 ? 204.870 216.840 125.204 1.00 33.94  ? 205  GLN B CG  1 
ATOM   1090  C CD  . GLN A 1 173 ? 204.118 217.544 124.090 1.00 33.94  ? 205  GLN B CD  1 
ATOM   1091  O OE1 . GLN A 1 173 ? 203.085 218.175 124.271 1.00 33.94  ? 205  GLN B OE1 1 
ATOM   1092  N NE2 . GLN A 1 173 ? 204.618 217.456 122.882 1.00 33.94  ? 205  GLN B NE2 1 
ATOM   1093  N N   . ALA A 1 174 ? 203.258 215.049 129.164 1.00 21.52  ? 206  ALA B N   1 
ATOM   1094  C CA  . ALA A 1 174 ? 202.622 214.931 130.455 1.00 21.52  ? 206  ALA B CA  1 
ATOM   1095  C C   . ALA A 1 174 ? 203.644 215.144 131.568 1.00 21.52  ? 206  ALA B C   1 
ATOM   1096  O O   . ALA A 1 174 ? 203.366 215.943 132.459 1.00 21.52  ? 206  ALA B O   1 
ATOM   1097  C CB  . ALA A 1 174 ? 201.974 213.559 130.580 1.00 29.07  ? 206  ALA B CB  1 
ATOM   1098  N N   . GLN A 1 175 ? 204.832 214.514 131.511 1.00 22.86  ? 207  GLN B N   1 
ATOM   1099  C CA  . GLN A 1 175 ? 205.766 214.717 132.600 1.00 22.86  ? 207  GLN B CA  1 
ATOM   1100  C C   . GLN A 1 175 ? 206.160 216.143 132.680 1.00 22.86  ? 207  GLN B C   1 
ATOM   1101  O O   . GLN A 1 175 ? 206.317 216.691 133.769 1.00 22.86  ? 207  GLN B O   1 
ATOM   1102  C CB  . GLN A 1 175 ? 207.035 213.900 132.434 1.00 31.07  ? 207  GLN B CB  1 
ATOM   1103  C CG  . GLN A 1 175 ? 208.026 214.064 133.618 1.00 31.07  ? 207  GLN B CG  1 
ATOM   1104  C CD  . GLN A 1 175 ? 207.459 213.587 134.918 1.00 31.07  ? 207  GLN B CD  1 
ATOM   1105  O OE1 . GLN A 1 175 ? 206.928 212.481 134.951 1.00 31.07  ? 207  GLN B OE1 1 
ATOM   1106  N NE2 . GLN A 1 175 ? 207.570 214.371 135.992 1.00 31.07  ? 207  GLN B NE2 1 
ATOM   1107  N N   . ALA A 1 176 ? 206.318 216.754 131.534 1.00 19.88  ? 208  ALA B N   1 
ATOM   1108  C CA  . ALA A 1 176 ? 206.716 218.108 131.517 1.00 19.88  ? 208  ALA B CA  1 
ATOM   1109  C C   . ALA A 1 176 ? 205.681 218.981 132.153 1.00 19.88  ? 208  ALA B C   1 
ATOM   1110  O O   . ALA A 1 176 ? 206.025 219.882 132.911 1.00 19.88  ? 208  ALA B O   1 
ATOM   1111  C CB  . ALA A 1 176 ? 206.932 218.516 130.127 1.00 26.86  ? 208  ALA B CB  1 
ATOM   1112  N N   . MET A 1 177 ? 204.419 218.750 131.848 1.00 22.01  ? 209  MET B N   1 
ATOM   1113  C CA  . MET A 1 177 ? 203.350 219.496 132.454 1.00 22.01  ? 209  MET B CA  1 
ATOM   1114  C C   . MET A 1 177 ? 203.385 219.328 133.973 1.00 22.01  ? 209  MET B C   1 
ATOM   1115  O O   . MET A 1 177 ? 203.203 220.296 134.703 1.00 22.01  ? 209  MET B O   1 
ATOM   1116  C CB  . MET A 1 177 ? 202.049 219.001 131.836 1.00 30.62  ? 209  MET B CB  1 
ATOM   1117  C CG  . MET A 1 177 ? 200.844 219.783 132.337 1.00 30.62  ? 209  MET B CG  1 
ATOM   1118  S SD  . MET A 1 177 ? 200.909 221.541 131.957 1.00 30.62  ? 209  MET B SD  1 
ATOM   1119  C CE  . MET A 1 177 ? 200.804 221.501 130.149 1.00 30.62  ? 209  MET B CE  1 
ATOM   1120  N N   . VAL A 1 178 ? 203.697 218.125 134.463 1.00 19.24  ? 210  VAL B N   1 
ATOM   1121  C CA  . VAL A 1 178 ? 203.736 217.900 135.888 1.00 19.24  ? 210  VAL B CA  1 
ATOM   1122  C C   . VAL A 1 178 ? 204.876 218.710 136.467 1.00 19.24  ? 210  VAL B C   1 
ATOM   1123  O O   . VAL A 1 178 ? 204.711 219.358 137.503 1.00 19.24  ? 210  VAL B O   1 
ATOM   1124  C CB  . VAL A 1 178 ? 203.927 216.408 136.224 1.00 27.09  ? 210  VAL B CB  1 
ATOM   1125  C CG1 . VAL A 1 178 ? 204.151 216.213 137.731 1.00 27.09  ? 210  VAL B CG1 1 
ATOM   1126  C CG2 . VAL A 1 178 ? 202.718 215.645 135.806 1.00 27.09  ? 210  VAL B CG2 1 
ATOM   1127  N N   . ASP A 1 179 ? 206.028 218.696 135.799 1.00 19.59  ? 211  ASP B N   1 
ATOM   1128  C CA  . ASP A 1 179 ? 207.178 219.423 136.284 1.00 19.59  ? 211  ASP B CA  1 
ATOM   1129  C C   . ASP A 1 179 ? 206.912 220.912 136.327 1.00 19.59  ? 211  ASP B C   1 
ATOM   1130  O O   . ASP A 1 179 ? 207.386 221.592 137.237 1.00 19.59  ? 211  ASP B O   1 
ATOM   1131  C CB  . ASP A 1 179 ? 208.388 219.183 135.380 1.00 24.95  ? 211  ASP B CB  1 
ATOM   1132  C CG  . ASP A 1 179 ? 208.960 217.778 135.458 1.00 24.95  ? 211  ASP B CG  1 
ATOM   1133  O OD1 . ASP A 1 179 ? 208.641 217.048 136.369 1.00 24.95  ? 211  ASP B OD1 1 
ATOM   1134  O OD2 . ASP A 1 179 ? 209.757 217.445 134.608 1.00 24.95  ? 211  ASP B OD2 1 
ATOM   1135  N N   . ILE A 1 180 ? 206.177 221.451 135.356 1.00 20.21  ? 212  ILE B N   1 
ATOM   1136  C CA  . ILE A 1 180 ? 205.869 222.878 135.296 1.00 20.21  ? 212  ILE B CA  1 
ATOM   1137  C C   . ILE A 1 180 ? 204.929 223.254 136.420 1.00 20.21  ? 212  ILE B C   1 
ATOM   1138  O O   . ILE A 1 180 ? 205.160 224.218 137.140 1.00 20.21  ? 212  ILE B O   1 
ATOM   1139  C CB  . ILE A 1 180 ? 205.245 223.241 133.946 1.00 28.73  ? 212  ILE B CB  1 
ATOM   1140  C CG1 . ILE A 1 180 ? 206.318 223.120 132.861 1.00 28.73  ? 212  ILE B CG1 1 
ATOM   1141  C CG2 . ILE A 1 180 ? 204.689 224.669 133.960 1.00 28.73  ? 212  ILE B CG2 1 
ATOM   1142  C CD1 . ILE A 1 180 ? 205.718 223.068 131.459 1.00 28.73  ? 212  ILE B CD1 1 
ATOM   1143  N N   . VAL A 1 181 ? 203.888 222.460 136.654 1.00 20.04  ? 213  VAL B N   1 
ATOM   1144  C CA  . VAL A 1 181 ? 202.976 222.683 137.781 1.00 20.04  ? 213  VAL B CA  1 
ATOM   1145  C C   . VAL A 1 181 ? 203.732 222.666 139.103 1.00 20.04  ? 213  VAL B C   1 
ATOM   1146  O O   . VAL A 1 181 ? 203.516 223.503 139.982 1.00 20.04  ? 213  VAL B O   1 
ATOM   1147  C CB  . VAL A 1 181 ? 201.886 221.606 137.768 1.00 28.22  ? 213  VAL B CB  1 
ATOM   1148  C CG1 . VAL A 1 181 ? 200.984 221.670 139.006 1.00 28.22  ? 213  VAL B CG1 1 
ATOM   1149  C CG2 . VAL A 1 181 ? 200.983 221.781 136.545 1.00 28.22  ? 213  VAL B CG2 1 
ATOM   1150  N N   . ARG A 1 182 ? 204.677 221.738 139.232 1.00 21.92  ? 214  ARG B N   1 
ATOM   1151  C CA  . ARG A 1 182 ? 205.538 221.661 140.403 1.00 21.92  ? 214  ARG B CA  1 
ATOM   1152  C C   . ARG A 1 182 ? 206.511 222.819 140.459 1.00 21.92  ? 214  ARG B C   1 
ATOM   1153  O O   . ARG A 1 182 ? 206.737 223.336 141.542 1.00 21.92  ? 214  ARG B O   1 
ATOM   1154  C CB  . ARG A 1 182 ? 206.233 220.298 140.441 1.00 30.78  ? 214  ARG B CB  1 
ATOM   1155  C CG  . ARG A 1 182 ? 205.235 219.136 140.624 1.00 30.78  ? 214  ARG B CG  1 
ATOM   1156  C CD  . ARG A 1 182 ? 204.802 218.848 142.067 1.00 30.78  ? 214  ARG B CD  1 
ATOM   1157  N NE  . ARG A 1 182 ? 204.104 219.975 142.718 1.00 30.78  ? 214  ARG B NE  1 
ATOM   1158  C CZ  . ARG A 1 182 ? 204.509 220.638 143.781 1.00 30.78  ? 214  ARG B CZ  1 
ATOM   1159  N NH1 . ARG A 1 182 ? 203.790 221.605 144.254 1.00 30.78  ? 214  ARG B NH1 1 
ATOM   1160  N NH2 . ARG A 1 182 ? 205.624 220.371 144.386 1.00 30.78  ? 214  ARG B NH2 1 
ATOM   1161  N N   . ALA A 1 183 ? 207.011 223.307 139.339 1.00 17.44  ? 215  ALA B N   1 
ATOM   1162  C CA  . ALA A 1 183 ? 207.804 224.528 139.283 1.00 17.44  ? 215  ALA B CA  1 
ATOM   1163  C C   . ALA A 1 183 ? 206.980 225.758 139.685 1.00 17.44  ? 215  ALA B C   1 
ATOM   1164  O O   . ALA A 1 183 ? 207.474 226.638 140.382 1.00 17.44  ? 215  ALA B O   1 
ATOM   1165  C CB  . ALA A 1 183 ? 208.394 224.672 137.881 1.00 23.56  ? 215  ALA B CB  1 
ATOM   1166  N N   . LEU A 1 184 ? 205.698 225.790 139.344 1.00 18.28  ? 216  LEU B N   1 
ATOM   1167  C CA  . LEU A 1 184 ? 204.755 226.793 139.822 1.00 18.28  ? 216  LEU B CA  1 
ATOM   1168  C C   . LEU A 1 184 ? 204.401 226.613 141.292 1.00 18.28  ? 216  LEU B C   1 
ATOM   1169  O O   . LEU A 1 184 ? 203.727 227.463 141.868 1.00 18.28  ? 216  LEU B O   1 
ATOM   1170  C CB  . LEU A 1 184 ? 203.496 226.726 138.965 1.00 25.98  ? 216  LEU B CB  1 
ATOM   1171  C CG  . LEU A 1 184 ? 203.782 227.167 137.528 1.00 25.98  ? 216  LEU B CG  1 
ATOM   1172  C CD1 . LEU A 1 184 ? 202.674 226.653 136.626 1.00 25.98  ? 216  LEU B CD1 1 
ATOM   1173  C CD2 . LEU A 1 184 ? 203.848 228.690 137.434 1.00 25.98  ? 216  LEU B CD2 1 
ATOM   1174  N N   . LYS A 1 185 ? 204.851 225.517 141.904 1.00 23.62  ? 217  LYS B N   1 
ATOM   1175  C CA  . LYS A 1 185 ? 204.551 225.150 143.288 1.00 23.62  ? 217  LYS B CA  1 
ATOM   1176  C C   . LYS A 1 185 ? 203.053 225.064 143.520 1.00 23.62  ? 217  LYS B C   1 
ATOM   1177  O O   . LYS A 1 185 ? 202.551 225.349 144.602 1.00 23.62  ? 217  LYS B O   1 
ATOM   1178  C CB  . LYS A 1 185 ? 205.280 226.083 144.275 1.00 33.79  ? 217  LYS B CB  1 
ATOM   1179  C CG  . LYS A 1 185 ? 206.781 226.230 143.987 1.00 33.79  ? 217  LYS B CG  1 
ATOM   1180  C CD  . LYS A 1 185 ? 207.550 224.912 144.168 1.00 33.79  ? 217  LYS B CD  1 
ATOM   1181  C CE  . LYS A 1 185 ? 208.743 224.848 143.215 1.00 33.79  ? 217  LYS B CE  1 
ATOM   1182  N NZ  . LYS A 1 185 ? 209.321 223.484 143.180 1.00 33.79  ? 217  LYS B NZ  1 
ATOM   1183  N N   . TRP A 1 186 ? 202.328 224.687 142.481 1.00 26.18  ? 218  TRP B N   1 
ATOM   1184  C CA  . TRP A 1 186 ? 200.915 224.398 142.579 1.00 26.18  ? 218  TRP B CA  1 
ATOM   1185  C C   . TRP A 1 186 ? 200.695 222.952 142.911 1.00 26.18  ? 218  TRP B C   1 
ATOM   1186  O O   . TRP A 1 186 ? 201.538 222.089 142.671 1.00 26.18  ? 218  TRP B O   1 
ATOM   1187  C CB  . TRP A 1 186 ? 200.243 224.786 141.288 1.00 35.05  ? 218  TRP B CB  1 
ATOM   1188  C CG  . TRP A 1 186 ? 200.168 226.250 141.091 1.00 35.05  ? 218  TRP B CG  1 
ATOM   1189  C CD1 . TRP A 1 186 ? 200.616 227.219 141.922 1.00 35.05  ? 218  TRP B CD1 1 
ATOM   1190  C CD2 . TRP A 1 186 ? 199.766 226.910 139.876 1.00 35.05  ? 218  TRP B CD2 1 
ATOM   1191  N NE1 . TRP A 1 186 ? 200.604 228.422 141.253 1.00 35.05  ? 218  TRP B NE1 1 
ATOM   1192  C CE2 . TRP A 1 186 ? 200.158 228.270 139.963 1.00 35.05  ? 218  TRP B CE2 1 
ATOM   1193  C CE3 . TRP A 1 186 ? 199.227 226.451 138.664 1.00 35.05  ? 218  TRP B CE3 1 
ATOM   1194  C CZ2 . TRP A 1 186 ? 200.119 229.116 138.856 1.00 35.05  ? 218  TRP B CZ2 1 
ATOM   1195  C CZ3 . TRP A 1 186 ? 199.160 227.300 137.551 1.00 35.05  ? 218  TRP B CZ3 1 
ATOM   1196  C CH2 . TRP A 1 186 ? 199.648 228.608 137.637 1.00 35.05  ? 218  TRP B CH2 1 
ATOM   1197  N N   . ASN A 1 187 ? 199.534 222.704 143.488 1.00 32.46  ? 219  ASN B N   1 
ATOM   1198  C CA  . ASN A 1 187 ? 199.200 221.427 144.069 1.00 32.46  ? 219  ASN B CA  1 
ATOM   1199  C C   . ASN A 1 187 ? 197.821 220.972 143.655 1.00 32.46  ? 219  ASN B C   1 
ATOM   1200  O O   . ASN A 1 187 ? 197.429 219.889 144.037 1.00 32.46  ? 219  ASN B O   1 
ATOM   1201  C CB  . ASN A 1 187 ? 199.276 221.487 145.598 1.00 43.18  ? 219  ASN B CB  1 
ATOM   1202  C CG  . ASN A 1 187 ? 200.667 221.593 146.178 1.00 43.18  ? 219  ASN B CG  1 
ATOM   1203  O OD1 . ASN A 1 187 ? 201.653 221.229 145.567 1.00 43.18  ? 219  ASN B OD1 1 
ATOM   1204  N ND2 . ASN A 1 187 ? 200.792 222.105 147.377 1.00 43.18  ? 219  ASN B ND2 1 
ATOM   1205  N N   . TYR A 1 188 ? 197.033 221.788 142.973 1.00 36.81  ? 220  TYR B N   1 
ATOM   1206  C CA  . TYR A 1 188 ? 195.610 221.529 142.945 1.00 36.81  ? 220  TYR B CA  1 
ATOM   1207  C C   . TYR A 1 188 ? 194.965 222.162 141.735 1.00 36.81  ? 220  TYR B C   1 
ATOM   1208  O O   . TYR A 1 188 ? 194.911 223.385 141.644 1.00 36.81  ? 220  TYR B O   1 
ATOM   1209  C CB  . TYR A 1 188 ? 195.058 222.068 144.237 1.00 49.41  ? 220  TYR B CB  1 
ATOM   1210  C CG  . TYR A 1 188 ? 193.600 221.791 144.414 1.00 49.41  ? 220  TYR B CG  1 
ATOM   1211  C CD1 . TYR A 1 188 ? 192.686 222.718 143.915 1.00 49.41  ? 220  TYR B CD1 1 
ATOM   1212  C CD2 . TYR A 1 188 ? 193.157 220.647 145.088 1.00 49.41  ? 220  TYR B CD2 1 
ATOM   1213  C CE1 . TYR A 1 188 ? 191.316 222.560 144.152 1.00 49.41  ? 220  TYR B CE1 1 
ATOM   1214  C CE2 . TYR A 1 188 ? 191.785 220.486 145.346 1.00 49.41  ? 220  TYR B CE2 1 
ATOM   1215  C CZ  . TYR A 1 188 ? 190.870 221.462 144.906 1.00 49.41  ? 220  TYR B CZ  1 
ATOM   1216  O OH  . TYR A 1 188 ? 189.562 221.381 145.247 1.00 49.41  ? 220  TYR B OH  1 
ATOM   1217  N N   . VAL A 1 189 ? 194.562 221.328 140.786 1.00 23.82  ? 221  VAL B N   1 
ATOM   1218  C CA  . VAL A 1 189 ? 194.361 221.749 139.390 1.00 23.82  ? 221  VAL B CA  1 
ATOM   1219  C C   . VAL A 1 189 ? 193.282 220.946 138.674 1.00 23.82  ? 221  VAL B C   1 
ATOM   1220  O O   . VAL A 1 189 ? 193.007 219.803 139.033 1.00 23.82  ? 221  VAL B O   1 
ATOM   1221  C CB  . VAL A 1 189 ? 195.679 221.647 138.599 1.00 33.54  ? 221  VAL B CB  1 
ATOM   1222  C CG1 . VAL A 1 189 ? 196.780 222.544 139.175 1.00 33.54  ? 221  VAL B CG1 1 
ATOM   1223  C CG2 . VAL A 1 189 ? 196.219 220.213 138.533 1.00 33.54  ? 221  VAL B CG2 1 
ATOM   1224  N N   . SER A 1 190 ? 192.702 221.531 137.635 1.00 19.16  ? 222  SER B N   1 
ATOM   1225  C CA  . SER A 1 190 ? 191.586 220.951 136.938 1.00 19.16  ? 222  SER B CA  1 
ATOM   1226  C C   . SER A 1 190 ? 192.078 220.697 135.542 1.00 19.16  ? 222  SER B C   1 
ATOM   1227  O O   . SER A 1 190 ? 192.838 221.506 135.004 1.00 19.16  ? 222  SER B O   1 
ATOM   1228  C CB  . SER A 1 190 ? 190.417 221.895 136.925 1.00 25.52  ? 222  SER B CB  1 
ATOM   1229  O OG  . SER A 1 190 ? 189.966 222.171 138.224 1.00 25.52  ? 222  SER B OG  1 
ATOM   1230  N N   . THR A 1 191 ? 191.664 219.603 134.940 1.00 16.69  ? 223  THR B N   1 
ATOM   1231  C CA  . THR A 1 191 ? 192.116 219.339 133.591 1.00 16.69  ? 223  THR B CA  1 
ATOM   1232  C C   . THR A 1 191 ? 190.947 219.155 132.670 1.00 16.69  ? 223  THR B C   1 
ATOM   1233  O O   . THR A 1 191 ? 189.872 218.731 133.096 1.00 16.69  ? 223  THR B O   1 
ATOM   1234  C CB  . THR A 1 191 ? 192.951 218.051 133.553 1.00 22.85  ? 223  THR B CB  1 
ATOM   1235  O OG1 . THR A 1 191 ? 192.110 216.951 133.913 1.00 22.85  ? 223  THR B OG1 1 
ATOM   1236  C CG2 . THR A 1 191 ? 194.099 218.108 134.564 1.00 22.85  ? 223  THR B CG2 1 
ATOM   1237  N N   . VAL A 1 192 ? 191.156 219.466 131.407 1.00 19.95  ? 224  VAL B N   1 
ATOM   1238  C CA  . VAL A 1 192 ? 190.120 219.249 130.428 1.00 19.95  ? 224  VAL B CA  1 
ATOM   1239  C C   . VAL A 1 192 ? 190.735 218.647 129.154 1.00 19.95  ? 224  VAL B C   1 
ATOM   1240  O O   . VAL A 1 192 ? 191.836 219.022 128.731 1.00 19.95  ? 224  VAL B O   1 
ATOM   1241  C CB  . VAL A 1 192 ? 189.395 220.563 130.090 1.00 28.09  ? 224  VAL B CB  1 
ATOM   1242  C CG1 . VAL A 1 192 ? 188.232 220.315 129.173 1.00 28.09  ? 224  VAL B CG1 1 
ATOM   1243  C CG2 . VAL A 1 192 ? 188.982 221.324 131.359 1.00 28.09  ? 224  VAL B CG2 1 
ATOM   1244  N N   . ALA A 1 193 ? 190.064 217.679 128.531 1.00 30.91  ? 225  ALA B N   1 
ATOM   1245  C CA  . ALA A 1 193 ? 190.470 217.119 127.242 1.00 30.91  ? 225  ALA B CA  1 
ATOM   1246  C C   . ALA A 1 193 ? 189.250 216.700 126.449 1.00 30.91  ? 225  ALA B C   1 
ATOM   1247  O O   . ALA A 1 193 ? 188.271 216.221 127.010 1.00 30.91  ? 225  ALA B O   1 
ATOM   1248  C CB  . ALA A 1 193 ? 191.399 215.927 127.444 1.00 41.76  ? 225  ALA B CB  1 
ATOM   1249  N N   . SER A 1 194 ? 189.285 216.853 125.137 1.00 41.41  ? 226  SER B N   1 
ATOM   1250  C CA  . SER A 1 194 ? 188.232 216.311 124.288 1.00 41.41  ? 226  SER B CA  1 
ATOM   1251  C C   . SER A 1 194 ? 188.534 214.874 123.890 1.00 41.41  ? 226  SER B C   1 
ATOM   1252  O O   . SER A 1 194 ? 189.639 214.366 124.093 1.00 41.41  ? 226  SER B O   1 
ATOM   1253  C CB  . SER A 1 194 ? 187.994 217.206 123.078 1.00 55.16  ? 226  SER B CB  1 
ATOM   1254  O OG  . SER A 1 194 ? 189.177 217.347 122.333 1.00 55.16  ? 226  SER B OG  1 
ATOM   1255  N N   . GLU A 1 195 ? 187.517 214.204 123.365 1.00 56.58  ? 227  GLU B N   1 
ATOM   1256  C CA  . GLU A 1 195 ? 187.566 212.806 122.950 1.00 56.58  ? 227  GLU B CA  1 
ATOM   1257  C C   . GLU A 1 195 ? 188.643 212.485 121.908 1.00 56.58  ? 227  GLU B C   1 
ATOM   1258  O O   . GLU A 1 195 ? 189.138 213.343 121.182 1.00 56.58  ? 227  GLU B O   1 
ATOM   1259  C CB  . GLU A 1 195 ? 186.193 212.423 122.395 1.00 74.57  ? 227  GLU B CB  1 
ATOM   1260  C CG  . GLU A 1 195 ? 185.167 212.119 123.486 1.00 74.57  ? 227  GLU B CG  1 
ATOM   1261  C CD  . GLU A 1 195 ? 183.875 211.584 122.858 1.00 74.57  ? 227  GLU B CD  1 
ATOM   1262  O OE1 . GLU A 1 195 ? 183.245 212.312 122.057 1.00 74.57  ? 227  GLU B OE1 1 
ATOM   1263  O OE2 . GLU A 1 195 ? 183.487 210.436 123.162 1.00 74.57  ? 227  GLU B OE2 1 
ATOM   1264  N N   . GLY A 1 196 ? 188.945 211.203 121.766 1.00 42.87  ? 228  GLY B N   1 
ATOM   1265  C CA  . GLY A 1 196 ? 189.961 210.701 120.855 1.00 42.87  ? 228  GLY B CA  1 
ATOM   1266  C C   . GLY A 1 196 ? 191.256 210.423 121.590 1.00 42.87  ? 228  GLY B C   1 
ATOM   1267  O O   . GLY A 1 196 ? 191.584 211.090 122.573 1.00 42.87  ? 228  GLY B O   1 
ATOM   1268  N N   . SER A 1 197 ? 191.985 209.412 121.118 1.00 33.31  ? 229  SER B N   1 
ATOM   1269  C CA  . SER A 1 197 ? 193.111 208.814 121.839 1.00 33.31  ? 229  SER B CA  1 
ATOM   1270  C C   . SER A 1 197 ? 194.110 209.845 122.318 1.00 33.31  ? 229  SER B C   1 
ATOM   1271  O O   . SER A 1 197 ? 194.603 209.736 123.436 1.00 33.31  ? 229  SER B O   1 
ATOM   1272  C CB  . SER A 1 197 ? 193.802 207.776 120.961 1.00 44.37  ? 229  SER B CB  1 
ATOM   1273  O OG  . SER A 1 197 ? 194.389 208.335 119.803 1.00 44.37  ? 229  SER B OG  1 
ATOM   1274  N N   . TYR A 1 198 ? 194.351 210.870 121.511 1.00 22.28  ? 230  TYR B N   1 
ATOM   1275  C CA  . TYR A 1 198 ? 195.271 211.932 121.863 1.00 22.28  ? 230  TYR B CA  1 
ATOM   1276  C C   . TYR A 1 198 ? 194.874 212.602 123.173 1.00 22.28  ? 230  TYR B C   1 
ATOM   1277  O O   . TYR A 1 198 ? 195.587 212.484 124.164 1.00 22.28  ? 230  TYR B O   1 
ATOM   1278  C CB  . TYR A 1 198 ? 195.358 212.937 120.714 1.00 29.91  ? 230  TYR B CB  1 
ATOM   1279  C CG  . TYR A 1 198 ? 196.186 214.130 121.058 1.00 29.91  ? 230  TYR B CG  1 
ATOM   1280  C CD1 . TYR A 1 198 ? 197.415 213.949 121.707 1.00 29.91  ? 230  TYR B CD1 1 
ATOM   1281  C CD2 . TYR A 1 198 ? 195.709 215.411 120.774 1.00 29.91  ? 230  TYR B CD2 1 
ATOM   1282  C CE1 . TYR A 1 198 ? 198.123 215.059 122.179 1.00 29.91  ? 230  TYR B CE1 1 
ATOM   1283  C CE2 . TYR A 1 198 ? 196.437 216.519 121.215 1.00 29.91  ? 230  TYR B CE2 1 
ATOM   1284  C CZ  . TYR A 1 198 ? 197.616 216.341 121.965 1.00 29.91  ? 230  TYR B CZ  1 
ATOM   1285  O OH  . TYR A 1 198 ? 198.267 217.391 122.514 1.00 29.91  ? 230  TYR B OH  1 
ATOM   1286  N N   . GLY A 1 199 ? 193.705 213.232 123.208 1.00 25.97  ? 231  GLY B N   1 
ATOM   1287  C CA  . GLY A 1 199 ? 193.204 213.850 124.423 1.00 25.97  ? 231  GLY B CA  1 
ATOM   1288  C C   . GLY A 1 199 ? 193.103 212.836 125.548 1.00 25.97  ? 231  GLY B C   1 
ATOM   1289  O O   . GLY A 1 199 ? 193.759 212.963 126.577 1.00 25.97  ? 231  GLY B O   1 
ATOM   1290  N N   . GLU A 1 200 ? 192.299 211.803 125.360 1.00 30.10  ? 232  GLU B N   1 
ATOM   1291  C CA  . GLU A 1 200 ? 191.866 210.977 126.485 1.00 30.10  ? 232  GLU B CA  1 
ATOM   1292  C C   . GLU A 1 200 ? 193.019 210.246 127.150 1.00 30.10  ? 232  GLU B C   1 
ATOM   1293  O O   . GLU A 1 200 ? 193.106 210.234 128.375 1.00 30.10  ? 232  GLU B O   1 
ATOM   1294  C CB  . GLU A 1 200 ? 190.775 210.001 126.050 1.00 39.67  ? 232  GLU B CB  1 
ATOM   1295  C CG  . GLU A 1 200 ? 189.558 210.769 125.532 1.00 39.67  ? 232  GLU B CG  1 
ATOM   1296  C CD  . GLU A 1 200 ? 188.404 209.833 125.192 1.00 39.67  ? 232  GLU B CD  1 
ATOM   1297  O OE1 . GLU A 1 200 ? 187.896 209.153 126.109 1.00 39.67  ? 232  GLU B OE1 1 
ATOM   1298  O OE2 . GLU A 1 200 ? 188.000 209.789 124.012 1.00 39.67  ? 232  GLU B OE2 1 
ATOM   1299  N N   . SER A 1 201 ? 193.958 209.700 126.386 1.00 32.37  ? 233  SER B N   1 
ATOM   1300  C CA  . SER A 1 201 ? 195.139 209.093 126.992 1.00 32.37  ? 233  SER B CA  1 
ATOM   1301  C C   . SER A 1 201 ? 196.147 210.137 127.431 1.00 32.37  ? 233  SER B C   1 
ATOM   1302  O O   . SER A 1 201 ? 196.854 209.921 128.409 1.00 32.37  ? 233  SER B O   1 
ATOM   1303  C CB  . SER A 1 201 ? 195.823 208.122 126.048 1.00 43.12  ? 233  SER B CB  1 
ATOM   1304  O OG  . SER A 1 201 ? 196.458 208.843 125.022 1.00 43.12  ? 233  SER B OG  1 
ATOM   1305  N N   . GLY A 1 202 ? 196.231 211.272 126.742 1.00 30.09  ? 234  GLY B N   1 
ATOM   1306  C CA  . GLY A 1 202 ? 197.238 212.265 127.062 1.00 30.09  ? 234  GLY B CA  1 
ATOM   1307  C C   . GLY A 1 202 ? 196.988 212.838 128.451 1.00 30.09  ? 234  GLY B C   1 
ATOM   1308  O O   . GLY A 1 202 ? 197.845 212.778 129.334 1.00 30.09  ? 234  GLY B O   1 
ATOM   1309  N N   . VAL A 1 203 ? 195.778 213.330 128.695 1.00 27.36  ? 235  VAL B N   1 
ATOM   1310  C CA  . VAL A 1 203 ? 195.483 213.883 130.011 1.00 27.36  ? 235  VAL B CA  1 
ATOM   1311  C C   . VAL A 1 203 ? 195.530 212.792 131.060 1.00 27.36  ? 235  VAL B C   1 
ATOM   1312  O O   . VAL A 1 203 ? 195.992 213.028 132.167 1.00 27.36  ? 235  VAL B O   1 
ATOM   1313  C CB  . VAL A 1 203 ? 194.156 214.624 130.006 1.00 38.53  ? 235  VAL B CB  1 
ATOM   1314  C CG1 . VAL A 1 203 ? 192.938 213.698 129.989 1.00 38.53  ? 235  VAL B CG1 1 
ATOM   1315  C CG2 . VAL A 1 203 ? 194.065 215.520 131.233 1.00 38.53  ? 235  VAL B CG2 1 
ATOM   1316  N N   . GLU A 1 204 ? 195.153 211.569 130.711 1.00 34.30  ? 236  GLU B N   1 
ATOM   1317  C CA  . GLU A 1 204 ? 195.295 210.471 131.645 1.00 34.30  ? 236  GLU B CA  1 
ATOM   1318  C C   . GLU A 1 204 ? 196.764 210.236 131.988 1.00 34.30  ? 236  GLU B C   1 
ATOM   1319  O O   . GLU A 1 204 ? 197.098 210.032 133.147 1.00 34.30  ? 236  GLU B O   1 
ATOM   1320  C CB  . GLU A 1 204 ? 194.632 209.223 131.070 1.00 45.20  ? 236  GLU B CB  1 
ATOM   1321  C CG  . GLU A 1 204 ? 194.580 208.079 132.080 1.00 45.20  ? 236  GLU B CG  1 
ATOM   1322  C CD  . GLU A 1 204 ? 193.802 208.456 133.349 1.00 45.20  ? 236  GLU B CD  1 
ATOM   1323  O OE1 . GLU A 1 204 ? 192.766 209.150 133.237 1.00 45.20  ? 236  GLU B OE1 1 
ATOM   1324  O OE2 . GLU A 1 204 ? 194.220 208.033 134.451 1.00 45.20  ? 236  GLU B OE2 1 
ATOM   1325  N N   . ALA A 1 205 ? 197.678 210.356 131.032 1.00 30.45  ? 237  ALA B N   1 
ATOM   1326  C CA  . ALA A 1 205 ? 199.097 210.311 131.334 1.00 30.45  ? 237  ALA B CA  1 
ATOM   1327  C C   . ALA A 1 205 ? 199.485 211.456 132.277 1.00 30.45  ? 237  ALA B C   1 
ATOM   1328  O O   . ALA A 1 205 ? 200.161 211.220 133.274 1.00 30.45  ? 237  ALA B O   1 
ATOM   1329  C CB  . ALA A 1 205 ? 199.895 210.296 130.030 1.00 41.14  ? 237  ALA B CB  1 
ATOM   1330  N N   . PHE A 1 206 ? 198.998 212.679 132.075 1.00 27.29  ? 238  PHE B N   1 
ATOM   1331  C CA  . PHE A 1 206 ? 199.265 213.763 133.030 1.00 27.29  ? 238  PHE B CA  1 
ATOM   1332  C C   . PHE A 1 206 ? 198.735 213.460 134.423 1.00 27.29  ? 238  PHE B C   1 
ATOM   1333  O O   . PHE A 1 206 ? 199.440 213.668 135.408 1.00 27.29  ? 238  PHE B O   1 
ATOM   1334  C CB  . PHE A 1 206 ? 198.699 215.087 132.534 1.00 36.91  ? 238  PHE B CB  1 
ATOM   1335  C CG  . PHE A 1 206 ? 198.757 216.169 133.591 1.00 36.91  ? 238  PHE B CG  1 
ATOM   1336  C CD1 . PHE A 1 206 ? 199.961 216.838 133.833 1.00 36.91  ? 238  PHE B CD1 1 
ATOM   1337  C CD2 . PHE A 1 206 ? 197.634 216.434 134.385 1.00 36.91  ? 238  PHE B CD2 1 
ATOM   1338  C CE1 . PHE A 1 206 ? 200.047 217.769 134.872 1.00 36.91  ? 238  PHE B CE1 1 
ATOM   1339  C CE2 . PHE A 1 206 ? 197.729 217.352 135.436 1.00 36.91  ? 238  PHE B CE2 1 
ATOM   1340  C CZ  . PHE A 1 206 ? 198.938 218.010 135.688 1.00 36.91  ? 238  PHE B CZ  1 
ATOM   1341  N N   . ILE A 1 207 ? 197.529 212.924 134.530 1.00 33.55  ? 239  ILE B N   1 
ATOM   1342  C CA  . ILE A 1 207 ? 196.955 212.526 135.793 1.00 33.55  ? 239  ILE B CA  1 
ATOM   1343  C C   . ILE A 1 207 ? 197.793 211.487 136.484 1.00 33.55  ? 239  ILE B C   1 
ATOM   1344  O O   . ILE A 1 207 ? 198.054 211.588 137.687 1.00 33.55  ? 239  ILE B O   1 
ATOM   1345  C CB  . ILE A 1 207 ? 195.527 211.978 135.586 1.00 47.69  ? 239  ILE B CB  1 
ATOM   1346  C CG1 . ILE A 1 207 ? 194.586 213.139 135.154 1.00 47.69  ? 239  ILE B CG1 1 
ATOM   1347  C CG2 . ILE A 1 207 ? 195.027 211.247 136.852 1.00 47.69  ? 239  ILE B CG2 1 
ATOM   1348  C CD1 . ILE A 1 207 ? 193.252 212.730 134.592 1.00 47.69  ? 239  ILE B CD1 1 
ATOM   1349  N N   . GLN A 1 208 ? 198.230 210.483 135.753 1.00 36.97  ? 240  GLN B N   1 
ATOM   1350  C CA  . GLN A 1 208 ? 199.003 209.470 136.407 1.00 36.97  ? 240  GLN B CA  1 
ATOM   1351  C C   . GLN A 1 208 ? 200.376 209.948 136.802 1.00 36.97  ? 240  GLN B C   1 
ATOM   1352  O O   . GLN A 1 208 ? 200.842 209.603 137.884 1.00 36.97  ? 240  GLN B O   1 
ATOM   1353  C CB  . GLN A 1 208 ? 199.107 208.242 135.524 1.00 50.25  ? 240  GLN B CB  1 
ATOM   1354  C CG  . GLN A 1 208 ? 197.775 207.558 135.310 1.00 50.25  ? 240  GLN B CG  1 
ATOM   1355  C CD  . GLN A 1 208 ? 197.110 207.206 136.616 1.00 50.25  ? 240  GLN B CD  1 
ATOM   1356  O OE1 . GLN A 1 208 ? 197.771 206.798 137.593 1.00 50.25  ? 240  GLN B OE1 1 
ATOM   1357  N NE2 . GLN A 1 208 ? 195.793 207.341 136.657 1.00 50.25  ? 240  GLN B NE2 1 
ATOM   1358  N N   . LYS A 1 209 ? 201.009 210.795 135.999 1.00 32.30  ? 241  LYS B N   1 
ATOM   1359  C CA  . LYS A 1 209 ? 202.332 211.236 136.382 1.00 32.30  ? 241  LYS B CA  1 
ATOM   1360  C C   . LYS A 1 209 ? 202.223 212.192 137.560 1.00 32.30  ? 241  LYS B C   1 
ATOM   1361  O O   . LYS A 1 209 ? 203.102 212.213 138.430 1.00 32.30  ? 241  LYS B O   1 
ATOM   1362  C CB  . LYS A 1 209 ? 203.069 211.855 135.192 1.00 46.20  ? 241  LYS B CB  1 
ATOM   1363  C CG  . LYS A 1 209 ? 203.351 210.879 133.995 1.00 46.20  ? 241  LYS B CG  1 
ATOM   1364  C CD  . LYS A 1 209 ? 204.103 209.588 134.372 1.00 46.20  ? 241  LYS B CD  1 
ATOM   1365  C CE  . LYS A 1 209 ? 205.543 209.837 134.734 1.00 46.20  ? 241  LYS B CE  1 
ATOM   1366  N NZ  . LYS A 1 209 ? 206.257 208.582 135.059 1.00 46.20  ? 241  LYS B NZ  1 
ATOM   1367  N N   . SER A 1 210 ? 201.134 212.967 137.613 1.00 34.97  ? 242  SER B N   1 
ATOM   1368  C CA  . SER A 1 210 ? 200.924 213.896 138.704 1.00 34.97  ? 242  SER B CA  1 
ATOM   1369  C C   . SER A 1 210 ? 200.746 213.109 139.983 1.00 34.97  ? 242  SER B C   1 
ATOM   1370  O O   . SER A 1 210 ? 201.332 213.450 141.018 1.00 34.97  ? 242  SER B O   1 
ATOM   1371  C CB  . SER A 1 210 ? 199.664 214.710 138.465 1.00 46.58  ? 242  SER B CB  1 
ATOM   1372  O OG  . SER A 1 210 ? 199.792 215.532 137.355 1.00 46.58  ? 242  SER B OG  1 
ATOM   1373  N N   . ARG A 1 211 ? 199.976 212.030 139.917 1.00 41.40  ? 243  ARG B N   1 
ATOM   1374  C CA  . ARG A 1 211 ? 199.739 211.179 141.063 1.00 41.40  ? 243  ARG B CA  1 
ATOM   1375  C C   . ARG A 1 211 ? 201.023 210.475 141.503 1.00 41.40  ? 243  ARG B C   1 
ATOM   1376  O O   . ARG A 1 211 ? 201.242 210.343 142.699 1.00 41.40  ? 243  ARG B O   1 
ATOM   1377  C CB  . ARG A 1 211 ? 198.630 210.219 140.658 1.00 58.14  ? 243  ARG B CB  1 
ATOM   1378  C CG  . ARG A 1 211 ? 198.103 209.409 141.848 1.00 58.14  ? 243  ARG B CG  1 
ATOM   1379  C CD  . ARG A 1 211 ? 197.341 208.158 141.396 1.00 58.14  ? 243  ARG B CD  1 
ATOM   1380  N NE  . ARG A 1 211 ? 198.097 207.354 140.415 1.00 58.14  ? 243  ARG B NE  1 
ATOM   1381  C CZ  . ARG A 1 211 ? 199.326 206.891 140.502 1.00 58.14  ? 243  ARG B CZ  1 
ATOM   1382  N NH1 . ARG A 1 211 ? 199.873 206.379 139.447 1.00 58.14  ? 243  ARG B NH1 1 
ATOM   1383  N NH2 . ARG A 1 211 ? 200.031 206.927 141.593 1.00 58.14  ? 243  ARG B NH2 1 
ATOM   1384  N N   . GLU A 1 212 ? 201.893 210.072 140.576 1.00 47.87  ? 244  GLU B N   1 
ATOM   1385  C CA  . GLU A 1 212 ? 203.160 209.457 140.933 1.00 47.87  ? 244  GLU B CA  1 
ATOM   1386  C C   . GLU A 1 212 ? 204.072 210.449 141.622 1.00 47.87  ? 244  GLU B C   1 
ATOM   1387  O O   . GLU A 1 212 ? 204.753 210.101 142.586 1.00 47.87  ? 244  GLU B O   1 
ATOM   1388  C CB  . GLU A 1 212 ? 203.879 208.911 139.705 1.00 63.09  ? 244  GLU B CB  1 
ATOM   1389  C CG  . GLU A 1 212 ? 203.254 207.680 139.057 1.00 63.09  ? 244  GLU B CG  1 
ATOM   1390  C CD  . GLU A 1 212 ? 203.997 207.293 137.802 1.00 63.09  ? 244  GLU B CD  1 
ATOM   1391  O OE1 . GLU A 1 212 ? 204.949 207.979 137.487 1.00 63.09  ? 244  GLU B OE1 1 
ATOM   1392  O OE2 . GLU A 1 212 ? 203.633 206.346 137.153 1.00 63.09  ? 244  GLU B OE2 1 
ATOM   1393  N N   . ASP A 1 213 ? 204.068 211.700 141.162 1.00 39.05  ? 245  ASP B N   1 
ATOM   1394  C CA  . ASP A 1 213 ? 204.883 212.710 141.806 1.00 39.05  ? 245  ASP B CA  1 
ATOM   1395  C C   . ASP A 1 213 ? 204.412 212.893 143.231 1.00 39.05  ? 245  ASP B C   1 
ATOM   1396  O O   . ASP A 1 213 ? 205.196 212.899 144.182 1.00 39.05  ? 245  ASP B O   1 
ATOM   1397  C CB  . ASP A 1 213 ? 204.728 214.050 141.105 1.00 49.73  ? 245  ASP B CB  1 
ATOM   1398  C CG  . ASP A 1 213 ? 205.604 215.080 141.691 1.00 49.73  ? 245  ASP B CG  1 
ATOM   1399  O OD1 . ASP A 1 213 ? 206.754 215.117 141.337 1.00 49.73  ? 245  ASP B OD1 1 
ATOM   1400  O OD2 . ASP A 1 213 ? 205.146 215.822 142.549 1.00 49.73  ? 245  ASP B OD2 1 
ATOM   1401  N N   . GLY A 1 214 ? 203.089 213.001 143.380 1.00 37.73  ? 246  GLY B N   1 
ATOM   1402  C CA  . GLY A 1 214 ? 202.388 213.197 144.639 1.00 37.73  ? 246  GLY B CA  1 
ATOM   1403  C C   . GLY A 1 214 ? 202.242 214.664 145.051 1.00 37.73  ? 246  GLY B C   1 
ATOM   1404  O O   . GLY A 1 214 ? 201.362 214.976 145.849 1.00 37.73  ? 246  GLY B O   1 
ATOM   1405  N N   . GLY A 1 215 ? 203.019 215.590 144.479 1.00 36.54  ? 247  GLY B N   1 
ATOM   1406  C CA  . GLY A 1 215 ? 202.946 217.016 144.813 1.00 36.54  ? 247  GLY B CA  1 
ATOM   1407  C C   . GLY A 1 215 ? 201.676 217.726 144.333 1.00 36.54  ? 247  GLY B C   1 
ATOM   1408  O O   . GLY A 1 215 ? 201.543 218.933 144.513 1.00 36.54  ? 247  GLY B O   1 
ATOM   1409  N N   . VAL A 1 216 ? 200.746 217.010 143.698 1.00 35.73  ? 248  VAL B N   1 
ATOM   1410  C CA  . VAL A 1 216 ? 199.516 217.566 143.128 1.00 35.73  ? 248  VAL B CA  1 
ATOM   1411  C C   . VAL A 1 216 ? 198.330 216.642 143.364 1.00 35.73  ? 248  VAL B C   1 
ATOM   1412  O O   . VAL A 1 216 ? 198.450 215.423 143.283 1.00 35.73  ? 248  VAL B O   1 
ATOM   1413  C CB  . VAL A 1 216 ? 199.671 217.833 141.620 1.00 50.32  ? 248  VAL B CB  1 
ATOM   1414  C CG1 . VAL A 1 216 ? 198.428 218.471 140.987 1.00 50.32  ? 248  VAL B CG1 1 
ATOM   1415  C CG2 . VAL A 1 216 ? 200.845 218.766 141.314 1.00 50.32  ? 248  VAL B CG2 1 
ATOM   1416  N N   . CYS A 1 217 ? 197.167 217.241 143.567 1.00 38.61  ? 249  CYS B N   1 
ATOM   1417  C CA  . CYS A 1 217 ? 195.861 216.620 143.563 1.00 38.61  ? 249  CYS B CA  1 
ATOM   1418  C C   . CYS A 1 217 ? 195.021 217.204 142.420 1.00 38.61  ? 249  CYS B C   1 
ATOM   1419  O O   . CYS A 1 217 ? 195.065 218.395 142.120 1.00 38.61  ? 249  CYS B O   1 
ATOM   1420  C CB  . CYS A 1 217 ? 195.177 216.863 144.908 1.00 51.43  ? 249  CYS B CB  1 
ATOM   1421  S SG  . CYS A 1 217 ? 196.210 216.743 146.394 1.00 51.43  ? 249  CYS B SG  1 
ATOM   1422  N N   . ILE A 1 218 ? 194.242 216.363 141.766 1.00 26.74  ? 250  ILE B N   1 
ATOM   1423  C CA  . ILE A 1 218 ? 193.398 216.764 140.650 1.00 26.74  ? 250  ILE B CA  1 
ATOM   1424  C C   . ILE A 1 218 ? 192.084 217.239 141.227 1.00 26.74  ? 250  ILE B C   1 
ATOM   1425  O O   . ILE A 1 218 ? 191.349 216.427 141.785 1.00 26.74  ? 250  ILE B O   1 
ATOM   1426  C CB  . ILE A 1 218 ? 193.191 215.580 139.693 1.00 38.01  ? 250  ILE B CB  1 
ATOM   1427  C CG1 . ILE A 1 218 ? 194.472 215.214 138.923 1.00 38.01  ? 250  ILE B CG1 1 
ATOM   1428  C CG2 . ILE A 1 218 ? 192.088 215.892 138.671 1.00 38.01  ? 250  ILE B CG2 1 
ATOM   1429  C CD1 . ILE A 1 218 ? 195.589 214.563 139.745 1.00 38.01  ? 250  ILE B CD1 1 
ATOM   1430  N N   . ALA A 1 219 ? 191.740 218.516 141.082 1.00 21.68  ? 251  ALA B N   1 
ATOM   1431  C CA  . ALA A 1 219 ? 190.410 218.936 141.466 1.00 21.68  ? 251  ALA B CA  1 
ATOM   1432  C C   . ALA A 1 219 ? 189.356 218.217 140.651 1.00 21.68  ? 251  ALA B C   1 
ATOM   1433  O O   . ALA A 1 219 ? 188.314 217.840 141.181 1.00 21.68  ? 251  ALA B O   1 
ATOM   1434  C CB  . ALA A 1 219 ? 190.285 220.436 141.282 1.00 29.29  ? 251  ALA B CB  1 
ATOM   1435  N N   . GLN A 1 220 ? 189.621 218.011 139.371 1.00 25.66  ? 252  GLN B N   1 
ATOM   1436  C CA  . GLN A 1 220 ? 188.646 217.397 138.491 1.00 25.66  ? 252  GLN B CA  1 
ATOM   1437  C C   . GLN A 1 220 ? 189.211 217.182 137.118 1.00 25.66  ? 252  GLN B C   1 
ATOM   1438  O O   . GLN A 1 220 ? 190.204 217.814 136.754 1.00 25.66  ? 252  GLN B O   1 
ATOM   1439  C CB  . GLN A 1 220 ? 187.365 218.222 138.412 1.00 34.88  ? 252  GLN B CB  1 
ATOM   1440  C CG  . GLN A 1 220 ? 187.539 219.595 137.890 1.00 34.88  ? 252  GLN B CG  1 
ATOM   1441  C CD  . GLN A 1 220 ? 186.248 220.319 137.947 1.00 34.88  ? 252  GLN B CD  1 
ATOM   1442  O OE1 . GLN A 1 220 ? 185.361 220.060 137.130 1.00 34.88  ? 252  GLN B OE1 1 
ATOM   1443  N NE2 . GLN A 1 220 ? 186.095 221.222 138.905 1.00 34.88  ? 252  GLN B NE2 1 
ATOM   1444  N N   . SER A 1 221 ? 188.536 216.348 136.342 1.00 23.61  ? 253  SER B N   1 
ATOM   1445  C CA  . SER A 1 221 ? 188.900 216.108 134.956 1.00 23.61  ? 253  SER B CA  1 
ATOM   1446  C C   . SER A 1 221 ? 187.648 216.102 134.106 1.00 23.61  ? 253  SER B C   1 
ATOM   1447  O O   . SER A 1 221 ? 186.694 215.364 134.367 1.00 23.61  ? 253  SER B O   1 
ATOM   1448  C CB  . SER A 1 221 ? 189.648 214.805 134.811 1.00 31.45  ? 253  SER B CB  1 
ATOM   1449  O OG  . SER A 1 221 ? 189.951 214.555 133.468 1.00 31.45  ? 253  SER B OG  1 
ATOM   1450  N N   . VAL A 1 222 ? 187.636 216.964 133.112 1.00 32.11  ? 254  VAL B N   1 
ATOM   1451  C CA  . VAL A 1 222 ? 186.482 217.156 132.269 1.00 32.11  ? 254  VAL B CA  1 
ATOM   1452  C C   . VAL A 1 222 ? 186.693 216.728 130.840 1.00 32.11  ? 254  VAL B C   1 
ATOM   1453  O O   . VAL A 1 222 ? 187.636 217.165 130.185 1.00 32.11  ? 254  VAL B O   1 
ATOM   1454  C CB  . VAL A 1 222 ? 186.130 218.635 132.261 1.00 45.22  ? 254  VAL B CB  1 
ATOM   1455  C CG1 . VAL A 1 222 ? 184.934 218.897 131.362 1.00 45.22  ? 254  VAL B CG1 1 
ATOM   1456  C CG2 . VAL A 1 222 ? 185.902 219.114 133.700 1.00 45.22  ? 254  VAL B CG2 1 
ATOM   1457  N N   . LYS A 1 223 ? 185.853 215.797 130.393 1.00 46.53  ? 255  LYS B N   1 
ATOM   1458  C CA  . LYS A 1 223 ? 185.832 215.315 129.017 1.00 46.53  ? 255  LYS B CA  1 
ATOM   1459  C C   . LYS A 1 223 ? 184.976 216.231 128.169 1.00 46.53  ? 255  LYS B C   1 
ATOM   1460  O O   . LYS A 1 223 ? 183.882 216.603 128.578 1.00 46.53  ? 255  LYS B O   1 
ATOM   1461  C CB  . LYS A 1 223 ? 185.289 213.885 128.984 1.00 66.56  ? 255  LYS B CB  1 
ATOM   1462  C CG  . LYS A 1 223 ? 185.149 213.338 127.558 1.00 66.56  ? 255  LYS B CG  1 
ATOM   1463  C CD  . LYS A 1 223 ? 184.824 211.842 127.555 1.00 66.56  ? 255  LYS B CD  1 
ATOM   1464  C CE  . LYS A 1 223 ? 183.506 211.535 128.261 1.00 66.56  ? 255  LYS B CE  1 
ATOM   1465  N NZ  . LYS A 1 223 ? 183.188 210.096 128.214 1.00 66.56  ? 255  LYS B NZ  1 
ATOM   1466  N N   . ILE A 1 224 ? 185.421 216.519 126.956 1.00 48.21  ? 256  ILE B N   1 
ATOM   1467  C CA  . ILE A 1 224 ? 184.586 217.171 125.952 1.00 48.21  ? 256  ILE B CA  1 
ATOM   1468  C C   . ILE A 1 224 ? 184.233 216.169 124.852 1.00 48.21  ? 256  ILE B C   1 
ATOM   1469  O O   . ILE A 1 224 ? 185.141 215.629 124.218 1.00 48.21  ? 256  ILE B O   1 
ATOM   1470  C CB  . ILE A 1 224 ? 185.287 218.430 125.435 1.00 68.52  ? 256  ILE B CB  1 
ATOM   1471  C CG1 . ILE A 1 224 ? 185.141 219.554 126.479 1.00 68.52  ? 256  ILE B CG1 1 
ATOM   1472  C CG2 . ILE A 1 224 ? 184.710 218.889 124.092 1.00 68.52  ? 256  ILE B CG2 1 
ATOM   1473  C CD1 . ILE A 1 224 ? 186.222 220.626 126.321 1.00 68.52  ? 256  ILE B CD1 1 
ATOM   1474  N N   . PRO A 1 225 ? 182.942 215.930 124.582 1.00 66.84  ? 257  PRO B N   1 
ATOM   1475  C CA  . PRO A 1 225 ? 182.512 215.172 123.419 1.00 66.84  ? 257  PRO B CA  1 
ATOM   1476  C C   . PRO A 1 225 ? 183.066 215.761 122.130 1.00 66.84  ? 257  PRO B C   1 
ATOM   1477  O O   . PRO A 1 225 ? 183.176 216.980 122.024 1.00 66.84  ? 257  PRO B O   1 
ATOM   1478  C CB  . PRO A 1 225 ? 180.986 215.255 123.406 1.00 114.21 ? 257  PRO B CB  1 
ATOM   1479  C CG  . PRO A 1 225 ? 180.633 215.521 124.861 1.00 114.21 ? 257  PRO B CG  1 
ATOM   1480  C CD  . PRO A 1 225 ? 181.789 216.390 125.329 1.00 114.21 ? 257  PRO B CD  1 
ATOM   1481  N N   . ARG A 1 226 ? 183.328 214.944 121.107 1.00 84.52  ? 258  ARG B N   1 
ATOM   1482  C CA  . ARG A 1 226 ? 183.666 215.477 119.774 1.00 84.52  ? 258  ARG B CA  1 
ATOM   1483  C C   . ARG A 1 226 ? 182.561 216.378 119.227 1.00 84.52  ? 258  ARG B C   1 
ATOM   1484  O O   . ARG A 1 226 ? 182.864 217.333 118.519 1.00 84.52  ? 258  ARG B O   1 
ATOM   1485  C CB  . ARG A 1 226 ? 183.927 214.369 118.748 1.00 118.70 ? 258  ARG B CB  1 
ATOM   1486  C CG  . ARG A 1 226 ? 185.050 213.410 119.138 1.00 118.70 ? 258  ARG B CG  1 
ATOM   1487  C CD  . ARG A 1 226 ? 185.420 212.511 117.959 1.00 118.70 ? 258  ARG B CD  1 
ATOM   1488  N NE  . ARG A 1 226 ? 186.084 211.282 118.425 1.00 118.70 ? 258  ARG B NE  1 
ATOM   1489  C CZ  . ARG A 1 226 ? 186.043 210.102 117.831 1.00 118.70 ? 258  ARG B CZ  1 
ATOM   1490  N NH1 . ARG A 1 226 ? 186.495 209.041 118.429 1.00 118.70 ? 258  ARG B NH1 1 
ATOM   1491  N NH2 . ARG A 1 226 ? 185.556 209.945 116.635 1.00 118.70 ? 258  ARG B NH2 1 
ATOM   1492  N N   . GLU A 1 227 ? 181.300 216.109 119.570 1.00 105.70 ? 259  GLU B N   1 
ATOM   1493  C CA  . GLU A 1 227 ? 180.142 216.909 119.153 1.00 105.70 ? 259  GLU B CA  1 
ATOM   1494  C C   . GLU A 1 227 ? 179.407 217.483 120.383 1.00 105.70 ? 259  GLU B C   1 
ATOM   1495  O O   . GLU A 1 227 ? 178.354 216.975 120.769 1.00 105.70 ? 259  GLU B O   1 
ATOM   1496  C CB  . GLU A 1 227 ? 179.247 216.063 118.232 1.00 139.30 ? 259  GLU B CB  1 
ATOM   1497  C CG  . GLU A 1 227 ? 179.979 215.461 117.020 1.00 139.30 ? 259  GLU B CG  1 
ATOM   1498  C CD  . GLU A 1 227 ? 180.792 216.479 116.206 1.00 139.30 ? 259  GLU B CD  1 
ATOM   1499  O OE1 . GLU A 1 227 ? 180.304 217.612 116.007 1.00 139.30 ? 259  GLU B OE1 1 
ATOM   1500  O OE2 . GLU A 1 227 ? 181.911 216.137 115.754 1.00 139.30 ? 259  GLU B OE2 1 
ATOM   1501  N N   . PRO A 1 228 ? 179.980 218.498 121.054 1.00 93.98  ? 260  PRO B N   1 
ATOM   1502  C CA  . PRO A 1 228 ? 179.458 219.050 122.284 1.00 93.98  ? 260  PRO B CA  1 
ATOM   1503  C C   . PRO A 1 228 ? 178.326 219.989 121.959 1.00 93.98  ? 260  PRO B C   1 
ATOM   1504  O O   . PRO A 1 228 ? 178.265 220.498 120.839 1.00 93.98  ? 260  PRO B O   1 
ATOM   1505  C CB  . PRO A 1 228 ? 180.649 219.803 122.834 1.00 160.59 ? 260  PRO B CB  1 
ATOM   1506  C CG  . PRO A 1 228 ? 181.360 220.275 121.603 1.00 160.59 ? 260  PRO B CG  1 
ATOM   1507  C CD  . PRO A 1 228 ? 181.164 219.207 120.581 1.00 160.59 ? 260  PRO B CD  1 
ATOM   1508  N N   . LYS A 1 229 ? 177.481 220.277 122.932 1.00 88.92  ? 261  LYS B N   1 
ATOM   1509  C CA  . LYS A 1 229 ? 176.443 221.265 122.716 1.00 88.92  ? 261  LYS B CA  1 
ATOM   1510  C C   . LYS A 1 229 ? 176.912 222.657 123.075 1.00 88.92  ? 261  LYS B C   1 
ATOM   1511  O O   . LYS A 1 229 ? 177.714 222.852 123.995 1.00 88.92  ? 261  LYS B O   1 
ATOM   1512  C CB  . LYS A 1 229 ? 175.200 220.929 123.537 1.00 132.22 ? 261  LYS B CB  1 
ATOM   1513  C CG  . LYS A 1 229 ? 174.582 219.550 123.261 1.00 132.22 ? 261  LYS B CG  1 
ATOM   1514  C CD  . LYS A 1 229 ? 174.075 219.416 121.822 1.00 132.22 ? 261  LYS B CD  1 
ATOM   1515  C CE  . LYS A 1 229 ? 173.348 218.095 121.615 1.00 132.22 ? 261  LYS B CE  1 
ATOM   1516  N NZ  . LYS A 1 229 ? 172.928 217.907 120.199 1.00 132.22 ? 261  LYS B NZ  1 
ATOM   1517  N N   . ALA A 1 230 ? 176.380 223.645 122.379 1.00 79.53  ? 262  ALA B N   1 
ATOM   1518  C CA  . ALA A 1 230 ? 176.704 225.006 122.728 1.00 79.53  ? 262  ALA B CA  1 
ATOM   1519  C C   . ALA A 1 230 ? 176.204 225.252 124.132 1.00 79.53  ? 262  ALA B C   1 
ATOM   1520  O O   . ALA A 1 230 ? 175.107 224.829 124.496 1.00 79.53  ? 262  ALA B O   1 
ATOM   1521  C CB  . ALA A 1 230 ? 176.080 225.980 121.752 1.00 107.44 ? 262  ALA B CB  1 
ATOM   1522  N N   . GLY A 1 231 ? 176.998 225.952 124.920 1.00 75.54  ? 263  GLY B N   1 
ATOM   1523  C CA  . GLY A 1 231 ? 176.636 226.264 126.292 1.00 75.54  ? 263  GLY B CA  1 
ATOM   1524  C C   . GLY A 1 231 ? 177.241 225.256 127.262 1.00 75.54  ? 263  GLY B C   1 
ATOM   1525  O O   . GLY A 1 231 ? 177.416 225.564 128.446 1.00 75.54  ? 263  GLY B O   1 
ATOM   1526  N N   . GLU A 1 232 ? 177.717 224.108 126.753 1.00 75.96  ? 264  GLU B N   1 
ATOM   1527  C CA  . GLU A 1 232 ? 178.303 223.101 127.625 1.00 75.96  ? 264  GLU B CA  1 
ATOM   1528  C C   . GLU A 1 232 ? 179.526 223.666 128.269 1.00 75.96  ? 264  GLU B C   1 
ATOM   1529  O O   . GLU A 1 232 ? 179.875 223.322 129.382 1.00 75.96  ? 264  GLU B O   1 
ATOM   1530  C CB  . GLU A 1 232 ? 178.660 221.818 126.892 1.00 100.11 ? 264  GLU B CB  1 
ATOM   1531  C CG  . GLU A 1 232 ? 179.195 220.721 127.831 1.00 100.11 ? 264  GLU B CG  1 
ATOM   1532  C CD  . GLU A 1 232 ? 178.164 220.266 128.876 1.00 100.11 ? 264  GLU B CD  1 
ATOM   1533  O OE1 . GLU A 1 232 ? 176.994 220.245 128.544 1.00 100.11 ? 264  GLU B OE1 1 
ATOM   1534  O OE2 . GLU A 1 232 ? 178.545 219.975 130.011 1.00 100.11 ? 264  GLU B OE2 1 
ATOM   1535  N N   . PHE A 1 233 ? 180.167 224.539 127.559 1.00 67.44  ? 265  PHE B N   1 
ATOM   1536  C CA  . PHE A 1 233 ? 181.385 225.165 127.945 1.00 67.44  ? 265  PHE B CA  1 
ATOM   1537  C C   . PHE A 1 233 ? 181.174 226.119 129.098 1.00 67.44  ? 265  PHE B C   1 
ATOM   1538  O O   . PHE A 1 233 ? 182.089 226.334 129.900 1.00 67.44  ? 265  PHE B O   1 
ATOM   1539  C CB  . PHE A 1 233 ? 181.908 225.818 126.691 1.00 91.20  ? 265  PHE B CB  1 
ATOM   1540  C CG  . PHE A 1 233 ? 182.200 224.722 125.779 1.00 91.20  ? 265  PHE B CG  1 
ATOM   1541  C CD1 . PHE A 1 233 ? 183.368 224.076 125.876 1.00 91.20  ? 265  PHE B CD1 1 
ATOM   1542  C CD2 . PHE A 1 233 ? 181.256 224.278 124.849 1.00 91.20  ? 265  PHE B CD2 1 
ATOM   1543  C CE1 . PHE A 1 233 ? 183.646 223.012 125.107 1.00 91.20  ? 265  PHE B CE1 1 
ATOM   1544  C CE2 . PHE A 1 233 ? 181.523 223.206 124.079 1.00 91.20  ? 265  PHE B CE2 1 
ATOM   1545  C CZ  . PHE A 1 233 ? 182.728 222.565 124.216 1.00 91.20  ? 265  PHE B CZ  1 
ATOM   1546  N N   . ASP A 1 234 ? 179.966 226.665 129.230 1.00 75.02  ? 266  ASP B N   1 
ATOM   1547  C CA  . ASP A 1 234 ? 179.707 227.568 130.317 1.00 75.02  ? 266  ASP B CA  1 
ATOM   1548  C C   . ASP A 1 234 ? 179.487 226.678 131.525 1.00 75.02  ? 266  ASP B C   1 
ATOM   1549  O O   . ASP A 1 234 ? 179.893 227.002 132.644 1.00 75.02  ? 266  ASP B O   1 
ATOM   1550  C CB  . ASP A 1 234 ? 178.472 228.421 130.021 1.00 95.53  ? 266  ASP B CB  1 
ATOM   1551  C CG  . ASP A 1 234 ? 178.643 229.319 128.764 1.00 95.53  ? 266  ASP B CG  1 
ATOM   1552  O OD1 . ASP A 1 234 ? 179.701 229.397 128.240 1.00 95.53  ? 266  ASP B OD1 1 
ATOM   1553  O OD2 . ASP A 1 234 ? 177.720 229.947 128.354 1.00 95.53  ? 266  ASP B OD2 1 
ATOM   1554  N N   . LYS A 1 235 ? 178.879 225.512 131.270 1.00 69.96  ? 267  LYS B N   1 
ATOM   1555  C CA  . LYS A 1 235 ? 178.633 224.531 132.314 1.00 69.96  ? 267  LYS B CA  1 
ATOM   1556  C C   . LYS A 1 235 ? 179.972 223.985 132.791 1.00 69.96  ? 267  LYS B C   1 
ATOM   1557  O O   . LYS A 1 235 ? 180.165 223.779 133.991 1.00 69.96  ? 267  LYS B O   1 
ATOM   1558  C CB  . LYS A 1 235 ? 177.773 223.384 131.811 1.00 100.07 ? 267  LYS B CB  1 
ATOM   1559  C CG  . LYS A 1 235 ? 176.364 223.744 131.474 1.00 100.07 ? 267  LYS B CG  1 
ATOM   1560  C CD  . LYS A 1 235 ? 175.651 222.538 130.921 1.00 100.07 ? 267  LYS B CD  1 
ATOM   1561  C CE  . LYS A 1 235 ? 174.267 222.860 130.432 1.00 100.07 ? 267  LYS B CE  1 
ATOM   1562  N NZ  . LYS A 1 235 ? 173.623 221.666 129.814 1.00 100.07 ? 267  LYS B NZ  1 
ATOM   1563  N N   . ILE A 1 236 ? 180.916 223.804 131.850 1.00 63.28  ? 268  ILE B N   1 
ATOM   1564  C CA  . ILE A 1 236 ? 182.237 223.309 132.185 1.00 63.28  ? 268  ILE B CA  1 
ATOM   1565  C C   . ILE A 1 236 ? 182.908 224.282 133.086 1.00 63.28  ? 268  ILE B C   1 
ATOM   1566  O O   . ILE A 1 236 ? 183.465 223.863 134.093 1.00 63.28  ? 268  ILE B O   1 
ATOM   1567  C CB  . ILE A 1 236 ? 183.148 223.060 130.947 1.00 89.94  ? 268  ILE B CB  1 
ATOM   1568  C CG1 . ILE A 1 236 ? 182.635 221.838 130.143 1.00 89.94  ? 268  ILE B CG1 1 
ATOM   1569  C CG2 . ILE A 1 236 ? 184.623 222.899 131.388 1.00 89.94  ? 268  ILE B CG2 1 
ATOM   1570  C CD1 . ILE A 1 236 ? 183.243 221.637 128.749 1.00 89.94  ? 268  ILE B CD1 1 
ATOM   1571  N N   . ILE A 1 237 ? 182.843 225.561 132.775 1.00 62.21  ? 269  ILE B N   1 
ATOM   1572  C CA  . ILE A 1 237 ? 183.481 226.498 133.655 1.00 62.21  ? 269  ILE B CA  1 
ATOM   1573  C C   . ILE A 1 237 ? 182.836 226.510 134.997 1.00 62.21  ? 269  ILE B C   1 
ATOM   1574  O O   . ILE A 1 237 ? 183.535 226.501 136.007 1.00 62.21  ? 269  ILE B O   1 
ATOM   1575  C CB  . ILE A 1 237 ? 183.497 227.896 133.082 1.00 88.42  ? 269  ILE B CB  1 
ATOM   1576  C CG1 . ILE A 1 237 ? 184.442 227.882 131.900 1.00 88.42  ? 269  ILE B CG1 1 
ATOM   1577  C CG2 . ILE A 1 237 ? 183.897 228.922 134.169 1.00 88.42  ? 269  ILE B CG2 1 
ATOM   1578  C CD1 . ILE A 1 237 ? 184.376 229.078 131.096 1.00 88.42  ? 269  ILE B CD1 1 
ATOM   1579  N N   . ARG A 1 238 ? 181.524 226.502 135.059 1.00 63.36  ? 270  ARG B N   1 
ATOM   1580  C CA  . ARG A 1 238 ? 180.949 226.523 136.372 1.00 63.36  ? 270  ARG B CA  1 
ATOM   1581  C C   . ARG A 1 238 ? 181.424 225.325 137.169 1.00 63.36  ? 270  ARG B C   1 
ATOM   1582  O O   . ARG A 1 238 ? 181.725 225.470 138.351 1.00 63.36  ? 270  ARG B O   1 
ATOM   1583  C CB  . ARG A 1 238 ? 179.452 226.606 136.288 1.00 88.98  ? 270  ARG B CB  1 
ATOM   1584  C CG  . ARG A 1 238 ? 178.997 227.980 135.849 1.00 88.98  ? 270  ARG B CG  1 
ATOM   1585  C CD  . ARG A 1 238 ? 177.561 228.191 136.024 1.00 88.98  ? 270  ARG B CD  1 
ATOM   1586  N NE  . ARG A 1 238 ? 176.777 227.335 135.152 1.00 88.98  ? 270  ARG B NE  1 
ATOM   1587  C CZ  . ARG A 1 238 ? 176.441 227.626 133.877 1.00 88.98  ? 270  ARG B CZ  1 
ATOM   1588  N NH1 . ARG A 1 238 ? 175.698 226.780 133.196 1.00 88.98  ? 270  ARG B NH1 1 
ATOM   1589  N NH2 . ARG A 1 238 ? 176.842 228.745 133.314 1.00 88.98  ? 270  ARG B NH2 1 
ATOM   1590  N N   . ARG A 1 239 ? 181.551 224.157 136.535 1.00 53.62  ? 271  ARG B N   1 
ATOM   1591  C CA  . ARG A 1 239 ? 182.080 223.010 137.248 1.00 53.62  ? 271  ARG B CA  1 
ATOM   1592  C C   . ARG A 1 239 ? 183.547 223.245 137.635 1.00 53.62  ? 271  ARG B C   1 
ATOM   1593  O O   . ARG A 1 239 ? 183.952 222.970 138.765 1.00 53.62  ? 271  ARG B O   1 
ATOM   1594  C CB  . ARG A 1 239 ? 181.969 221.748 136.411 1.00 75.31  ? 271  ARG B CB  1 
ATOM   1595  C CG  . ARG A 1 239 ? 180.551 221.234 136.235 1.00 75.31  ? 271  ARG B CG  1 
ATOM   1596  C CD  . ARG A 1 239 ? 180.520 219.851 135.696 1.00 75.31  ? 271  ARG B CD  1 
ATOM   1597  N NE  . ARG A 1 239 ? 181.039 219.730 134.322 1.00 75.31  ? 271  ARG B NE  1 
ATOM   1598  C CZ  . ARG A 1 239 ? 180.312 219.845 133.170 1.00 75.31  ? 271  ARG B CZ  1 
ATOM   1599  N NH1 . ARG A 1 239 ? 180.887 219.676 132.004 1.00 75.31  ? 271  ARG B NH1 1 
ATOM   1600  N NH2 . ARG A 1 239 ? 179.027 220.100 133.163 1.00 75.31  ? 271  ARG B NH2 1 
ATOM   1601  N N   . LEU A 1 240 ? 184.335 223.852 136.748 1.00 52.87  ? 272  LEU B N   1 
ATOM   1602  C CA  . LEU A 1 240 ? 185.746 224.105 137.021 1.00 52.87  ? 272  LEU B CA  1 
ATOM   1603  C C   . LEU A 1 240 ? 185.916 225.035 138.207 1.00 52.87  ? 272  LEU B C   1 
ATOM   1604  O O   . LEU A 1 240 ? 186.856 224.893 138.990 1.00 52.87  ? 272  LEU B O   1 
ATOM   1605  C CB  . LEU A 1 240 ? 186.453 224.707 135.799 1.00 75.15  ? 272  LEU B CB  1 
ATOM   1606  C CG  . LEU A 1 240 ? 186.648 223.775 134.554 1.00 75.15  ? 272  LEU B CG  1 
ATOM   1607  C CD1 . LEU A 1 240 ? 187.164 224.605 133.391 1.00 75.15  ? 272  LEU B CD1 1 
ATOM   1608  C CD2 . LEU A 1 240 ? 187.637 222.678 134.854 1.00 75.15  ? 272  LEU B CD2 1 
ATOM   1609  N N   . LEU A 1 241 ? 184.981 225.955 138.378 1.00 60.00  ? 273  LEU B N   1 
ATOM   1610  C CA  . LEU A 1 241 ? 185.024 226.920 139.457 1.00 60.00  ? 273  LEU B CA  1 
ATOM   1611  C C   . LEU A 1 241 ? 184.576 226.374 140.810 1.00 60.00  ? 273  LEU B C   1 
ATOM   1612  O O   . LEU A 1 241 ? 184.703 227.071 141.818 1.00 60.00  ? 273  LEU B O   1 
ATOM   1613  C CB  . LEU A 1 241 ? 184.111 228.106 139.122 1.00 85.28  ? 273  LEU B CB  1 
ATOM   1614  C CG  . LEU A 1 241 ? 184.478 228.961 137.893 1.00 85.28  ? 273  LEU B CG  1 
ATOM   1615  C CD1 . LEU A 1 241 ? 183.363 229.969 137.651 1.00 85.28  ? 273  LEU B CD1 1 
ATOM   1616  C CD2 . LEU A 1 241 ? 185.787 229.672 138.097 1.00 85.28  ? 273  LEU B CD2 1 
ATOM   1617  N N   . GLU A 1 242 ? 184.008 225.164 140.872 1.00 54.02  ? 274  GLU B N   1 
ATOM   1618  C CA  . GLU A 1 242 ? 183.555 224.673 142.169 1.00 54.02  ? 274  GLU B CA  1 
ATOM   1619  C C   . GLU A 1 242 ? 184.746 224.430 143.074 1.00 54.02  ? 274  GLU B C   1 
ATOM   1620  O O   . GLU A 1 242 ? 184.736 224.719 144.274 1.00 54.02  ? 274  GLU B O   1 
ATOM   1621  C CB  . GLU A 1 242 ? 182.762 223.371 142.026 1.00 71.19  ? 274  GLU B CB  1 
ATOM   1622  C CG  . GLU A 1 242 ? 181.397 223.512 141.373 1.00 71.19  ? 274  GLU B CG  1 
ATOM   1623  C CD  . GLU A 1 242 ? 180.689 222.188 141.209 1.00 71.19  ? 274  GLU B CD  1 
ATOM   1624  O OE1 . GLU A 1 242 ? 181.323 221.176 141.385 1.00 71.19  ? 274  GLU B OE1 1 
ATOM   1625  O OE2 . GLU A 1 242 ? 179.517 222.189 140.919 1.00 71.19  ? 274  GLU B OE2 1 
ATOM   1626  N N   . THR A 1 243 ? 185.812 223.929 142.488 1.00 49.22  ? 275  THR B N   1 
ATOM   1627  C CA  . THR A 1 243 ? 187.018 223.611 143.202 1.00 49.22  ? 275  THR B CA  1 
ATOM   1628  C C   . THR A 1 243 ? 187.868 224.850 143.296 1.00 49.22  ? 275  THR B C   1 
ATOM   1629  O O   . THR A 1 243 ? 188.913 224.965 142.655 1.00 49.22  ? 275  THR B O   1 
ATOM   1630  C CB  . THR A 1 243 ? 187.761 222.472 142.519 1.00 67.38  ? 275  THR B CB  1 
ATOM   1631  O OG1 . THR A 1 243 ? 187.956 222.797 141.146 1.00 67.38  ? 275  THR B OG1 1 
ATOM   1632  C CG2 . THR A 1 243 ? 186.933 221.194 142.620 1.00 67.38  ? 275  THR B CG2 1 
ATOM   1633  N N   . SER A 1 244 ? 187.416 225.751 144.156 1.00 52.50  ? 276  SER B N   1 
ATOM   1634  C CA  . SER A 1 244 ? 187.922 227.106 144.349 1.00 52.50  ? 276  SER B CA  1 
ATOM   1635  C C   . SER A 1 244 ? 189.354 227.176 144.850 1.00 52.50  ? 276  SER B C   1 
ATOM   1636  O O   . SER A 1 244 ? 189.972 228.241 144.844 1.00 52.50  ? 276  SER B O   1 
ATOM   1637  C CB  . SER A 1 244 ? 187.019 227.839 145.305 1.00 69.93  ? 276  SER B CB  1 
ATOM   1638  O OG  . SER A 1 244 ? 187.094 227.282 146.586 1.00 69.93  ? 276  SER B OG  1 
ATOM   1639  N N   . ASN A 1 245 ? 189.973 226.073 145.280 1.00 49.40  ? 277  ASN B N   1 
ATOM   1640  C CA  . ASN A 1 245 ? 191.409 226.059 145.611 1.00 49.40  ? 277  ASN B CA  1 
ATOM   1641  C C   . ASN A 1 245 ? 192.323 225.927 144.383 1.00 49.40  ? 277  ASN B C   1 
ATOM   1642  O O   . ASN A 1 245 ? 193.550 225.964 144.511 1.00 49.40  ? 277  ASN B O   1 
ATOM   1643  C CB  . ASN A 1 245 ? 191.739 224.970 146.633 1.00 65.71  ? 277  ASN B CB  1 
ATOM   1644  C CG  . ASN A 1 245 ? 190.661 224.737 147.660 1.00 65.71  ? 277  ASN B CG  1 
ATOM   1645  O OD1 . ASN A 1 245 ? 190.525 225.477 148.617 1.00 65.71  ? 277  ASN B OD1 1 
ATOM   1646  N ND2 . ASN A 1 245 ? 189.866 223.707 147.498 1.00 65.71  ? 277  ASN B ND2 1 
ATOM   1647  N N   . ALA A 1 246 ? 191.740 225.719 143.202 1.00 41.67  ? 278  ALA B N   1 
ATOM   1648  C CA  . ALA A 1 246 ? 192.419 225.757 141.919 1.00 41.67  ? 278  ALA B CA  1 
ATOM   1649  C C   . ALA A 1 246 ? 192.164 227.120 141.278 1.00 41.67  ? 278  ALA B C   1 
ATOM   1650  O O   . ALA A 1 246 ? 191.037 227.611 141.274 1.00 41.67  ? 278  ALA B O   1 
ATOM   1651  C CB  . ALA A 1 246 ? 191.905 224.633 141.007 1.00 56.29  ? 278  ALA B CB  1 
ATOM   1652  N N   . ARG A 1 247 ? 193.203 227.716 140.697 1.00 35.22  ? 279  ARG B N   1 
ATOM   1653  C CA  . ARG A 1 247 ? 193.120 228.926 139.865 1.00 35.22  ? 279  ARG B CA  1 
ATOM   1654  C C   . ARG A 1 247 ? 193.698 228.696 138.472 1.00 35.22  ? 279  ARG B C   1 
ATOM   1655  O O   . ARG A 1 247 ? 194.027 229.637 137.758 1.00 35.22  ? 279  ARG B O   1 
ATOM   1656  C CB  . ARG A 1 247 ? 193.804 230.089 140.591 1.00 51.49  ? 279  ARG B CB  1 
ATOM   1657  C CG  . ARG A 1 247 ? 193.148 230.449 141.935 1.00 51.49  ? 279  ARG B CG  1 
ATOM   1658  C CD  . ARG A 1 247 ? 191.718 230.970 141.771 1.00 51.49  ? 279  ARG B CD  1 
ATOM   1659  N NE  . ARG A 1 247 ? 191.698 232.181 140.936 1.00 51.49  ? 279  ARG B NE  1 
ATOM   1660  C CZ  . ARG A 1 247 ? 191.866 233.418 141.337 1.00 51.49  ? 279  ARG B CZ  1 
ATOM   1661  N NH1 . ARG A 1 247 ? 191.927 234.366 140.456 1.00 51.49  ? 279  ARG B NH1 1 
ATOM   1662  N NH2 . ARG A 1 247 ? 191.996 233.738 142.590 1.00 51.49  ? 279  ARG B NH2 1 
ATOM   1663  N N   . ALA A 1 248 ? 193.838 227.428 138.093 1.00 29.99  ? 280  ALA B N   1 
ATOM   1664  C CA  . ALA A 1 248 ? 194.482 227.017 136.868 1.00 29.99  ? 280  ALA B CA  1 
ATOM   1665  C C   . ALA A 1 248 ? 193.896 225.724 136.301 1.00 29.99  ? 280  ALA B C   1 
ATOM   1666  O O   . ALA A 1 248 ? 193.436 224.829 137.018 1.00 29.99  ? 280  ALA B O   1 
ATOM   1667  C CB  . ALA A 1 248 ? 195.979 226.863 137.109 1.00 40.52  ? 280  ALA B CB  1 
ATOM   1668  N N   . VAL A 1 249 ? 193.970 225.642 134.982 1.00 25.86  ? 281  VAL B N   1 
ATOM   1669  C CA  . VAL A 1 249 ? 193.403 224.576 134.160 1.00 25.86  ? 281  VAL B CA  1 
ATOM   1670  C C   . VAL A 1 249 ? 194.378 224.142 133.062 1.00 25.86  ? 281  VAL B C   1 
ATOM   1671  O O   . VAL A 1 249 ? 195.047 224.958 132.430 1.00 25.86  ? 281  VAL B O   1 
ATOM   1672  C CB  . VAL A 1 249 ? 192.015 224.943 133.599 1.00 36.42  ? 281  VAL B CB  1 
ATOM   1673  C CG1 . VAL A 1 249 ? 191.228 223.698 133.193 1.00 36.42  ? 281  VAL B CG1 1 
ATOM   1674  C CG2 . VAL A 1 249 ? 191.139 225.682 134.608 1.00 36.42  ? 281  VAL B CG2 1 
ATOM   1675  N N   . ILE A 1 250 ? 194.450 222.838 132.831 1.00 18.76  ? 282  ILE B N   1 
ATOM   1676  C CA  . ILE A 1 250 ? 195.338 222.202 131.860 1.00 18.76  ? 282  ILE B CA  1 
ATOM   1677  C C   . ILE A 1 250 ? 194.538 221.623 130.705 1.00 18.76  ? 282  ILE B C   1 
ATOM   1678  O O   . ILE A 1 250 ? 193.528 220.966 130.944 1.00 18.76  ? 282  ILE B O   1 
ATOM   1679  C CB  . ILE A 1 250 ? 196.132 221.122 132.587 1.00 26.66  ? 282  ILE B CB  1 
ATOM   1680  C CG1 . ILE A 1 250 ? 197.085 221.791 133.586 1.00 26.66  ? 282  ILE B CG1 1 
ATOM   1681  C CG2 . ILE A 1 250 ? 196.893 220.170 131.659 1.00 26.66  ? 282  ILE B CG2 1 
ATOM   1682  C CD1 . ILE A 1 250 ? 197.700 220.778 134.536 1.00 26.66  ? 282  ILE B CD1 1 
ATOM   1683  N N   . ILE A 1 251 ? 195.015 221.823 129.474 1.00 19.33  ? 283  ILE B N   1 
ATOM   1684  C CA  . ILE A 1 251 ? 194.331 221.427 128.250 1.00 19.33  ? 283  ILE B CA  1 
ATOM   1685  C C   . ILE A 1 251 ? 195.195 220.551 127.351 1.00 19.33  ? 283  ILE B C   1 
ATOM   1686  O O   . ILE A 1 251 ? 196.347 220.859 127.057 1.00 19.33  ? 283  ILE B O   1 
ATOM   1687  C CB  . ILE A 1 251 ? 193.870 222.660 127.457 1.00 27.47  ? 283  ILE B CB  1 
ATOM   1688  C CG1 . ILE A 1 251 ? 193.071 223.665 128.291 1.00 27.47  ? 283  ILE B CG1 1 
ATOM   1689  C CG2 . ILE A 1 251 ? 193.044 222.229 126.240 1.00 27.47  ? 283  ILE B CG2 1 
ATOM   1690  C CD1 . ILE A 1 251 ? 191.751 223.106 128.808 1.00 27.47  ? 283  ILE B CD1 1 
ATOM   1691  N N   . PHE A 1 252 ? 194.572 219.513 126.810 1.00 20.51  ? 284  PHE B N   1 
ATOM   1692  C CA  . PHE A 1 252 ? 195.095 218.712 125.712 1.00 20.51  ? 284  PHE B CA  1 
ATOM   1693  C C   . PHE A 1 252 ? 194.207 218.736 124.474 1.00 20.51  ? 284  PHE B C   1 
ATOM   1694  O O   . PHE A 1 252 ? 194.577 218.171 123.455 1.00 20.51  ? 284  PHE B O   1 
ATOM   1695  C CB  . PHE A 1 252 ? 195.239 217.283 126.203 1.00 27.74  ? 284  PHE B CB  1 
ATOM   1696  C CG  . PHE A 1 252 ? 196.372 217.102 127.169 1.00 27.74  ? 284  PHE B CG  1 
ATOM   1697  C CD1 . PHE A 1 252 ? 196.216 217.431 128.521 1.00 27.74  ? 284  PHE B CD1 1 
ATOM   1698  C CD2 . PHE A 1 252 ? 197.583 216.563 126.710 1.00 27.74  ? 284  PHE B CD2 1 
ATOM   1699  C CE1 . PHE A 1 252 ? 197.286 217.241 129.403 1.00 27.74  ? 284  PHE B CE1 1 
ATOM   1700  C CE2 . PHE A 1 252 ? 198.642 216.345 127.599 1.00 27.74  ? 284  PHE B CE2 1 
ATOM   1701  C CZ  . PHE A 1 252 ? 198.495 216.701 128.942 1.00 27.74  ? 284  PHE B CZ  1 
ATOM   1702  N N   . ALA A 1 253 ? 193.032 219.348 124.535 1.00 22.87  ? 285  ALA B N   1 
ATOM   1703  C CA  . ALA A 1 253 ? 192.037 219.350 123.464 1.00 22.87  ? 285  ALA B CA  1 
ATOM   1704  C C   . ALA A 1 253 ? 192.506 220.104 122.201 1.00 22.87  ? 285  ALA B C   1 
ATOM   1705  O O   . ALA A 1 253 ? 193.577 220.694 122.196 1.00 22.87  ? 285  ALA B O   1 
ATOM   1706  C CB  . ALA A 1 253 ? 190.770 219.949 124.072 1.00 30.90  ? 285  ALA B CB  1 
ATOM   1707  N N   . ASN A 1 254 ? 191.735 220.098 121.117 1.00 30.84  ? 286  ASN B N   1 
ATOM   1708  C CA  . ASN A 1 254 ? 192.093 220.847 119.914 1.00 30.84  ? 286  ASN B CA  1 
ATOM   1709  C C   . ASN A 1 254 ? 191.811 222.357 120.040 1.00 30.84  ? 286  ASN B C   1 
ATOM   1710  O O   . ASN A 1 254 ? 191.257 222.839 121.018 1.00 30.84  ? 286  ASN B O   1 
ATOM   1711  C CB  . ASN A 1 254 ? 191.403 220.203 118.704 1.00 41.02  ? 286  ASN B CB  1 
ATOM   1712  C CG  . ASN A 1 254 ? 189.919 220.503 118.607 1.00 41.02  ? 286  ASN B CG  1 
ATOM   1713  O OD1 . ASN A 1 254 ? 189.482 221.633 118.725 1.00 41.02  ? 286  ASN B OD1 1 
ATOM   1714  N ND2 . ASN A 1 254 ? 189.103 219.511 118.354 1.00 41.02  ? 286  ASN B ND2 1 
ATOM   1715  N N   . GLU A 1 255 ? 192.156 223.112 119.002 1.00 32.79  ? 287  GLU B N   1 
ATOM   1716  C CA  . GLU A 1 255 ? 191.977 224.565 118.911 1.00 32.79  ? 287  GLU B CA  1 
ATOM   1717  C C   . GLU A 1 255 ? 190.567 225.075 119.266 1.00 32.79  ? 287  GLU B C   1 
ATOM   1718  O O   . GLU A 1 255 ? 190.348 226.007 120.035 1.00 32.79  ? 287  GLU B O   1 
ATOM   1719  C CB  . GLU A 1 255 ? 192.295 224.906 117.451 1.00 43.21  ? 287  GLU B CB  1 
ATOM   1720  C CG  . GLU A 1 255 ? 192.058 226.377 117.115 1.00 43.21  ? 287  GLU B CG  1 
ATOM   1721  C CD  . GLU A 1 255 ? 192.215 226.677 115.622 1.00 43.21  ? 287  GLU B CD  1 
ATOM   1722  O OE1 . GLU A 1 255 ? 192.699 225.811 114.858 1.00 43.21  ? 287  GLU B OE1 1 
ATOM   1723  O OE2 . GLU A 1 255 ? 191.827 227.803 115.231 1.00 43.21  ? 287  GLU B OE2 1 
ATOM   1724  N N   . ASP A 1 256 ? 189.602 224.458 118.620 1.00 40.77  ? 288  ASP B N   1 
ATOM   1725  C CA  . ASP A 1 256 ? 188.204 224.858 118.592 1.00 40.77  ? 288  ASP B CA  1 
ATOM   1726  C C   . ASP A 1 256 ? 187.596 224.548 119.924 1.00 40.77  ? 288  ASP B C   1 
ATOM   1727  O O   . ASP A 1 256 ? 186.744 225.287 120.425 1.00 40.77  ? 288  ASP B O   1 
ATOM   1728  C CB  . ASP A 1 256 ? 187.440 224.137 117.489 1.00 51.92  ? 288  ASP B CB  1 
ATOM   1729  C CG  . ASP A 1 256 ? 187.813 224.567 116.078 1.00 51.92  ? 288  ASP B CG  1 
ATOM   1730  O OD1 . ASP A 1 256 ? 187.489 225.681 115.700 1.00 51.92  ? 288  ASP B OD1 1 
ATOM   1731  O OD2 . ASP A 1 256 ? 188.397 223.775 115.351 1.00 51.92  ? 288  ASP B OD2 1 
ATOM   1732  N N   . ASP A 1 257 ? 188.100 223.496 120.536 1.00 39.00  ? 289  ASP B N   1 
ATOM   1733  C CA  . ASP A 1 257 ? 187.621 223.069 121.826 1.00 39.00  ? 289  ASP B CA  1 
ATOM   1734  C C   . ASP A 1 257 ? 188.016 224.151 122.824 1.00 39.00  ? 289  ASP B C   1 
ATOM   1735  O O   . ASP A 1 257 ? 187.249 224.492 123.731 1.00 39.00  ? 289  ASP B O   1 
ATOM   1736  C CB  . ASP A 1 257 ? 188.321 221.783 122.201 1.00 49.66  ? 289  ASP B CB  1 
ATOM   1737  C CG  . ASP A 1 257 ? 188.035 220.502 121.307 1.00 49.66  ? 289  ASP B CG  1 
ATOM   1738  O OD1 . ASP A 1 257 ? 187.018 220.403 120.624 1.00 49.66  ? 289  ASP B OD1 1 
ATOM   1739  O OD2 . ASP A 1 257 ? 188.955 219.652 121.256 1.00 49.66  ? 289  ASP B OD2 1 
ATOM   1740  N N   . ILE A 1 258 ? 189.232 224.695 122.643 1.00 29.04  ? 290  ILE B N   1 
ATOM   1741  C CA  . ILE A 1 258 ? 189.778 225.745 123.480 1.00 29.04  ? 290  ILE B CA  1 
ATOM   1742  C C   . ILE A 1 258 ? 188.985 227.012 123.268 1.00 29.04  ? 290  ILE B C   1 
ATOM   1743  O O   . ILE A 1 258 ? 188.610 227.616 124.269 1.00 29.04  ? 290  ILE B O   1 
ATOM   1744  C CB  . ILE A 1 258 ? 191.273 225.998 123.241 1.00 41.28  ? 290  ILE B CB  1 
ATOM   1745  C CG1 . ILE A 1 258 ? 192.112 224.767 123.568 1.00 41.28  ? 290  ILE B CG1 1 
ATOM   1746  C CG2 . ILE A 1 258 ? 191.795 227.139 124.127 1.00 41.28  ? 290  ILE B CG2 1 
ATOM   1747  C CD1 . ILE A 1 258 ? 193.344 224.739 122.682 1.00 41.28  ? 290  ILE B CD1 1 
ATOM   1748  N N   . ARG A 1 259 ? 188.668 227.433 122.030 1.00 34.10  ? 291  ARG B N   1 
ATOM   1749  C CA  . ARG A 1 259 ? 187.875 228.626 121.930 1.00 34.10  ? 291  ARG B CA  1 
ATOM   1750  C C   . ARG A 1 259 ? 186.543 228.437 122.582 1.00 34.10  ? 291  ARG B C   1 
ATOM   1751  O O   . ARG A 1 259 ? 186.117 229.293 123.334 1.00 34.10  ? 291  ARG B O   1 
ATOM   1752  C CB  . ARG A 1 259 ? 187.694 229.087 120.508 1.00 49.85  ? 291  ARG B CB  1 
ATOM   1753  C CG  . ARG A 1 259 ? 188.885 229.806 119.918 1.00 49.85  ? 291  ARG B CG  1 
ATOM   1754  C CD  . ARG A 1 259 ? 188.505 230.449 118.645 1.00 49.85  ? 291  ARG B CD  1 
ATOM   1755  N NE  . ARG A 1 259 ? 188.334 229.443 117.623 1.00 49.85  ? 291  ARG B NE  1 
ATOM   1756  C CZ  . ARG A 1 259 ? 189.331 229.017 116.844 1.00 49.85  ? 291  ARG B CZ  1 
ATOM   1757  N NH1 . ARG A 1 259 ? 189.187 228.046 115.968 1.00 49.85  ? 291  ARG B NH1 1 
ATOM   1758  N NH2 . ARG A 1 259 ? 190.499 229.549 116.929 1.00 49.85  ? 291  ARG B NH2 1 
ATOM   1759  N N   . ARG A 1 260 ? 185.905 227.293 122.446 1.00 47.45  ? 292  ARG B N   1 
ATOM   1760  C CA  . ARG A 1 260 ? 184.611 227.234 123.088 1.00 47.45  ? 292  ARG B CA  1 
ATOM   1761  C C   . ARG A 1 260 ? 184.748 227.455 124.604 1.00 47.45  ? 292  ARG B C   1 
ATOM   1762  O O   . ARG A 1 260 ? 183.929 228.176 125.193 1.00 47.45  ? 292  ARG B O   1 
ATOM   1763  C CB  . ARG A 1 260 ? 183.927 225.947 122.724 1.00 66.64  ? 292  ARG B CB  1 
ATOM   1764  C CG  . ARG A 1 260 ? 183.480 225.921 121.257 1.00 66.64  ? 292  ARG B CG  1 
ATOM   1765  C CD  . ARG A 1 260 ? 182.582 224.798 120.940 1.00 66.64  ? 292  ARG B CD  1 
ATOM   1766  N NE  . ARG A 1 260 ? 183.249 223.543 121.177 1.00 66.64  ? 292  ARG B NE  1 
ATOM   1767  C CZ  . ARG A 1 260 ? 184.054 222.878 120.328 1.00 66.64  ? 292  ARG B CZ  1 
ATOM   1768  N NH1 . ARG A 1 260 ? 184.611 221.750 120.743 1.00 66.64  ? 292  ARG B NH1 1 
ATOM   1769  N NH2 . ARG A 1 260 ? 184.306 223.342 119.127 1.00 66.64  ? 292  ARG B NH2 1 
ATOM   1770  N N   . VAL A 1 261 ? 185.802 226.906 125.221 1.00 38.04  ? 293  VAL B N   1 
ATOM   1771  C CA  . VAL A 1 261 ? 186.039 227.125 126.645 1.00 38.04  ? 293  VAL B CA  1 
ATOM   1772  C C   . VAL A 1 261 ? 186.442 228.566 126.972 1.00 38.04  ? 293  VAL B C   1 
ATOM   1773  O O   . VAL A 1 261 ? 185.951 229.151 127.935 1.00 38.04  ? 293  VAL B O   1 
ATOM   1774  C CB  . VAL A 1 261 ? 187.157 226.195 127.184 1.00 53.57  ? 293  VAL B CB  1 
ATOM   1775  C CG1 . VAL A 1 261 ? 187.519 226.583 128.651 1.00 53.57  ? 293  VAL B CG1 1 
ATOM   1776  C CG2 . VAL A 1 261 ? 186.701 224.729 127.150 1.00 53.57  ? 293  VAL B CG2 1 
ATOM   1777  N N   . LEU A 1 262 ? 187.363 229.162 126.239 1.00 34.97  ? 294  LEU B N   1 
ATOM   1778  C CA  . LEU A 1 262 ? 187.797 230.503 126.580 1.00 34.97  ? 294  LEU B CA  1 
ATOM   1779  C C   . LEU A 1 262 ? 186.733 231.528 126.207 1.00 34.97  ? 294  LEU B C   1 
ATOM   1780  O O   . LEU A 1 262 ? 186.613 232.566 126.848 1.00 34.97  ? 294  LEU B O   1 
ATOM   1781  C CB  . LEU A 1 262 ? 189.155 230.748 125.934 1.00 49.70  ? 294  LEU B CB  1 
ATOM   1782  C CG  . LEU A 1 262 ? 190.246 229.836 126.512 1.00 49.70  ? 294  LEU B CG  1 
ATOM   1783  C CD1 . LEU A 1 262 ? 191.611 230.331 126.060 1.00 49.70  ? 294  LEU B CD1 1 
ATOM   1784  C CD2 . LEU A 1 262 ? 190.283 229.796 128.033 1.00 49.70  ? 294  LEU B CD2 1 
ATOM   1785  N N   . GLU A 1 263 ? 185.882 231.236 125.231 1.00 45.83  ? 295  GLU B N   1 
ATOM   1786  C CA  . GLU A 1 263 ? 184.804 232.137 124.882 1.00 45.83  ? 295  GLU B CA  1 
ATOM   1787  C C   . GLU A 1 263 ? 183.821 232.118 126.021 1.00 45.83  ? 295  GLU B C   1 
ATOM   1788  O O   . GLU A 1 263 ? 183.300 233.165 126.422 1.00 45.83  ? 295  GLU B O   1 
ATOM   1789  C CB  . GLU A 1 263 ? 184.164 231.727 123.562 1.00 60.40  ? 295  GLU B CB  1 
ATOM   1790  C CG  . GLU A 1 263 ? 185.056 231.966 122.329 1.00 60.40  ? 295  GLU B CG  1 
ATOM   1791  C CD  . GLU A 1 263 ? 184.494 231.383 121.087 1.00 60.40  ? 295  GLU B CD  1 
ATOM   1792  O OE1 . GLU A 1 263 ? 183.552 230.633 121.189 1.00 60.40  ? 295  GLU B OE1 1 
ATOM   1793  O OE2 . GLU A 1 263 ? 184.978 231.700 120.023 1.00 60.40  ? 295  GLU B OE2 1 
ATOM   1794  N N   . ALA A 1 264 ? 183.603 230.929 126.580 1.00 47.83  ? 296  ALA B N   1 
ATOM   1795  C CA  . ALA A 1 264 ? 182.757 230.795 127.733 1.00 47.83  ? 296  ALA B CA  1 
ATOM   1796  C C   . ALA A 1 264 ? 183.354 231.585 128.882 1.00 47.83  ? 296  ALA B C   1 
ATOM   1797  O O   . ALA A 1 264 ? 182.626 232.239 129.618 1.00 47.83  ? 296  ALA B O   1 
ATOM   1798  C CB  . ALA A 1 264 ? 182.599 229.337 128.080 1.00 64.62  ? 296  ALA B CB  1 
ATOM   1799  N N   . ALA A 1 265 ? 184.687 231.591 129.006 1.00 48.44  ? 297  ALA B N   1 
ATOM   1800  C CA  . ALA A 1 265 ? 185.338 232.351 130.066 1.00 48.44  ? 297  ALA B CA  1 
ATOM   1801  C C   . ALA A 1 265 ? 185.027 233.828 129.935 1.00 48.44  ? 297  ALA B C   1 
ATOM   1802  O O   . ALA A 1 265 ? 184.869 234.526 130.944 1.00 48.44  ? 297  ALA B O   1 
ATOM   1803  C CB  . ALA A 1 265 ? 186.844 232.135 130.063 1.00 65.44  ? 297  ALA B CB  1 
ATOM   1804  N N   . ARG A 1 266 ? 184.913 234.331 128.704 1.00 53.40  ? 298  ARG B N   1 
ATOM   1805  C CA  . ARG A 1 266 ? 184.583 235.740 128.599 1.00 53.40  ? 298  ARG B CA  1 
ATOM   1806  C C   . ARG A 1 266 ? 183.163 235.939 129.100 1.00 53.40  ? 298  ARG B C   1 
ATOM   1807  O O   . ARG A 1 266 ? 182.894 236.824 129.913 1.00 53.40  ? 298  ARG B O   1 
ATOM   1808  C CB  . ARG A 1 266 ? 184.607 236.246 127.160 1.00 75.00  ? 298  ARG B CB  1 
ATOM   1809  C CG  . ARG A 1 266 ? 185.943 236.316 126.493 1.00 75.00  ? 298  ARG B CG  1 
ATOM   1810  C CD  . ARG A 1 266 ? 185.878 236.996 125.152 1.00 75.00  ? 298  ARG B CD  1 
ATOM   1811  N NE  . ARG A 1 266 ? 185.061 236.226 124.202 1.00 75.00  ? 298  ARG B NE  1 
ATOM   1812  C CZ  . ARG A 1 266 ? 185.035 236.348 122.843 1.00 75.00  ? 298  ARG B CZ  1 
ATOM   1813  N NH1 . ARG A 1 266 ? 184.188 235.600 122.158 1.00 75.00  ? 298  ARG B NH1 1 
ATOM   1814  N NH2 . ARG A 1 266 ? 185.824 237.177 122.175 1.00 75.00  ? 298  ARG B NH2 1 
ATOM   1815  N N   . ARG A 1 267 ? 182.264 235.048 128.691 1.00 69.39  ? 299  ARG B N   1 
ATOM   1816  C CA  . ARG A 1 267 ? 180.855 235.157 129.062 1.00 69.39  ? 299  ARG B CA  1 
ATOM   1817  C C   . ARG A 1 267 ? 180.646 235.001 130.555 1.00 69.39  ? 299  ARG B C   1 
ATOM   1818  O O   . ARG A 1 267 ? 179.797 235.657 131.159 1.00 69.39  ? 299  ARG B O   1 
ATOM   1819  C CB  . ARG A 1 267 ? 180.025 234.128 128.325 1.00 97.45  ? 299  ARG B CB  1 
ATOM   1820  C CG  . ARG A 1 267 ? 179.867 234.405 126.852 1.00 97.45  ? 299  ARG B CG  1 
ATOM   1821  C CD  . ARG A 1 267 ? 178.813 233.556 126.238 1.00 97.45  ? 299  ARG B CD  1 
ATOM   1822  N NE  . ARG A 1 267 ? 179.153 232.146 126.291 1.00 97.45  ? 299  ARG B NE  1 
ATOM   1823  C CZ  . ARG A 1 267 ? 179.902 231.494 125.382 1.00 97.45  ? 299  ARG B CZ  1 
ATOM   1824  N NH1 . ARG A 1 267 ? 180.130 230.229 125.570 1.00 97.45  ? 299  ARG B NH1 1 
ATOM   1825  N NH2 . ARG A 1 267 ? 180.414 232.092 124.325 1.00 97.45  ? 299  ARG B NH2 1 
ATOM   1826  N N   . ALA A 1 268 ? 181.460 234.155 131.150 1.00 61.29  ? 300  ALA B N   1 
ATOM   1827  C CA  . ALA A 1 268 ? 181.435 233.822 132.551 1.00 61.29  ? 300  ALA B CA  1 
ATOM   1828  C C   . ALA A 1 268 ? 182.148 234.862 133.392 1.00 61.29  ? 300  ALA B C   1 
ATOM   1829  O O   . ALA A 1 268 ? 182.199 234.726 134.618 1.00 61.29  ? 300  ALA B O   1 
ATOM   1830  C CB  . ALA A 1 268 ? 182.088 232.466 132.753 1.00 82.80  ? 300  ALA B CB  1 
ATOM   1831  N N   . ASN A 1 269 ? 182.739 235.869 132.747 1.00 62.29  ? 301  ASN B N   1 
ATOM   1832  C CA  . ASN A 1 269 ? 183.504 236.902 133.406 1.00 62.29  ? 301  ASN B CA  1 
ATOM   1833  C C   . ASN A 1 269 ? 184.631 236.307 134.225 1.00 62.29  ? 301  ASN B C   1 
ATOM   1834  O O   . ASN A 1 269 ? 184.881 236.731 135.352 1.00 62.29  ? 301  ASN B O   1 
ATOM   1835  C CB  . ASN A 1 269 ? 182.595 237.756 134.276 1.00 82.86  ? 301  ASN B CB  1 
ATOM   1836  C CG  . ASN A 1 269 ? 183.202 239.087 134.650 1.00 82.86  ? 301  ASN B CG  1 
ATOM   1837  O OD1 . ASN A 1 269 ? 183.987 239.663 133.887 1.00 82.86  ? 301  ASN B OD1 1 
ATOM   1838  N ND2 . ASN A 1 269 ? 182.843 239.593 135.807 1.00 82.86  ? 301  ASN B ND2 1 
ATOM   1839  N N   . GLN A 1 270 ? 185.321 235.323 133.654 1.00 48.16  ? 302  GLN B N   1 
ATOM   1840  C CA  . GLN A 1 270 ? 186.429 234.671 134.322 1.00 48.16  ? 302  GLN B CA  1 
ATOM   1841  C C   . GLN A 1 270 ? 187.767 235.102 133.783 1.00 48.16  ? 302  GLN B C   1 
ATOM   1842  O O   . GLN A 1 270 ? 188.786 234.464 134.064 1.00 48.16  ? 302  GLN B O   1 
ATOM   1843  C CB  . GLN A 1 270 ? 186.285 233.164 134.248 1.00 65.46  ? 302  GLN B CB  1 
ATOM   1844  C CG  . GLN A 1 270 ? 185.051 232.708 134.898 1.00 65.46  ? 302  GLN B CG  1 
ATOM   1845  C CD  . GLN A 1 270 ? 184.994 233.100 136.321 1.00 65.46  ? 302  GLN B CD  1 
ATOM   1846  O OE1 . GLN A 1 270 ? 185.909 232.816 137.089 1.00 65.46  ? 302  GLN B OE1 1 
ATOM   1847  N NE2 . GLN A 1 270 ? 183.927 233.779 136.693 1.00 65.46  ? 302  GLN B NE2 1 
ATOM   1848  N N   . THR A 1 271 ? 187.768 236.133 132.968 1.00 46.58  ? 303  THR B N   1 
ATOM   1849  C CA  . THR A 1 271 ? 188.990 236.601 132.382 1.00 46.58  ? 303  THR B CA  1 
ATOM   1850  C C   . THR A 1 271 ? 189.928 236.989 133.521 1.00 46.58  ? 303  THR B C   1 
ATOM   1851  O O   . THR A 1 271 ? 189.563 237.756 134.408 1.00 46.58  ? 303  THR B O   1 
ATOM   1852  C CB  . THR A 1 271 ? 188.690 237.840 131.512 1.00 63.76  ? 303  THR B CB  1 
ATOM   1853  O OG1 . THR A 1 271 ? 187.688 237.509 130.527 1.00 63.76  ? 303  THR B OG1 1 
ATOM   1854  C CG2 . THR A 1 271 ? 189.942 238.287 130.792 1.00 63.76  ? 303  THR B CG2 1 
ATOM   1855  N N   . GLY A 1 272 ? 191.152 236.468 133.504 1.00 47.30  ? 304  GLY B N   1 
ATOM   1856  C CA  . GLY A 1 272 ? 192.140 236.746 134.543 1.00 47.30  ? 304  GLY B CA  1 
ATOM   1857  C C   . GLY A 1 272 ? 191.836 236.069 135.877 1.00 47.30  ? 304  GLY B C   1 
ATOM   1858  O O   . GLY A 1 272 ? 192.689 236.059 136.757 1.00 47.30  ? 304  GLY B O   1 
ATOM   1859  N N   . HIS A 1 273 ? 190.686 235.409 136.033 1.00 43.14  ? 305  HIS B N   1 
ATOM   1860  C CA  . HIS A 1 273 ? 190.499 234.501 137.156 1.00 43.14  ? 305  HIS B CA  1 
ATOM   1861  C C   . HIS A 1 273 ? 191.515 233.356 137.115 1.00 43.14  ? 305  HIS B C   1 
ATOM   1862  O O   . HIS A 1 273 ? 191.850 232.771 138.141 1.00 43.14  ? 305  HIS B O   1 
ATOM   1863  C CB  . HIS A 1 273 ? 189.094 233.908 137.130 1.00 57.30  ? 305  HIS B CB  1 
ATOM   1864  C CG  . HIS A 1 273 ? 188.873 233.027 138.324 1.00 57.30  ? 305  HIS B CG  1 
ATOM   1865  N ND1 . HIS A 1 273 ? 188.624 233.457 139.604 1.00 57.30  ? 305  HIS B ND1 1 
ATOM   1866  C CD2 . HIS A 1 273 ? 189.093 231.678 138.393 1.00 57.30  ? 305  HIS B CD2 1 
ATOM   1867  C CE1 . HIS A 1 273 ? 188.641 232.388 140.414 1.00 57.30  ? 305  HIS B CE1 1 
ATOM   1868  N NE2 . HIS A 1 273 ? 188.942 231.279 139.724 1.00 57.30  ? 305  HIS B NE2 1 
ATOM   1869  N N   . PHE A 1 274 ? 191.999 233.034 135.926 1.00 41.11  ? 306  PHE B N   1 
ATOM   1870  C CA  . PHE A 1 274 ? 192.645 231.777 135.651 1.00 41.11  ? 306  PHE B CA  1 
ATOM   1871  C C   . PHE A 1 274 ? 194.013 231.874 135.029 1.00 41.11  ? 306  PHE B C   1 
ATOM   1872  O O   . PHE A 1 274 ? 194.296 232.747 134.215 1.00 41.11  ? 306  PHE B O   1 
ATOM   1873  C CB  . PHE A 1 274 ? 191.803 231.028 134.630 1.00 55.59  ? 306  PHE B CB  1 
ATOM   1874  C CG  . PHE A 1 274 ? 190.641 230.327 135.230 1.00 55.59  ? 306  PHE B CG  1 
ATOM   1875  C CD1 . PHE A 1 274 ? 190.881 229.192 136.014 1.00 55.59  ? 306  PHE B CD1 1 
ATOM   1876  C CD2 . PHE A 1 274 ? 189.337 230.742 134.934 1.00 55.59  ? 306  PHE B CD2 1 
ATOM   1877  C CE1 . PHE A 1 274 ? 189.802 228.438 136.487 1.00 55.59  ? 306  PHE B CE1 1 
ATOM   1878  C CE2 . PHE A 1 274 ? 188.257 229.976 135.400 1.00 55.59  ? 306  PHE B CE2 1 
ATOM   1879  C CZ  . PHE A 1 274 ? 188.490 228.819 136.158 1.00 55.59  ? 306  PHE B CZ  1 
ATOM   1880  N N   . PHE A 1 275 ? 194.781 230.845 135.326 1.00 45.19  ? 307  PHE B N   1 
ATOM   1881  C CA  . PHE A 1 275 ? 195.834 230.358 134.462 1.00 45.19  ? 307  PHE B CA  1 
ATOM   1882  C C   . PHE A 1 275 ? 195.268 229.241 133.556 1.00 45.19  ? 307  PHE B C   1 
ATOM   1883  O O   . PHE A 1 275 ? 194.378 228.485 133.939 1.00 45.19  ? 307  PHE B O   1 
ATOM   1884  C CB  . PHE A 1 275 ? 196.983 229.853 135.324 1.00 61.11  ? 307  PHE B CB  1 
ATOM   1885  C CG  . PHE A 1 275 ? 198.108 230.842 135.532 1.00 61.11  ? 307  PHE B CG  1 
ATOM   1886  C CD1 . PHE A 1 275 ? 198.992 231.122 134.472 1.00 61.11  ? 307  PHE B CD1 1 
ATOM   1887  C CD2 . PHE A 1 275 ? 198.399 231.317 136.819 1.00 61.11  ? 307  PHE B CD2 1 
ATOM   1888  C CE1 . PHE A 1 275 ? 200.200 231.797 134.716 1.00 61.11  ? 307  PHE B CE1 1 
ATOM   1889  C CE2 . PHE A 1 275 ? 199.631 231.946 137.070 1.00 61.11  ? 307  PHE B CE2 1 
ATOM   1890  C CZ  . PHE A 1 275 ? 200.543 232.163 136.024 1.00 61.11  ? 307  PHE B CZ  1 
ATOM   1891  N N   . TRP A 1 276 ? 195.832 229.128 132.363 1.00 52.02  ? 308  TRP B N   1 
ATOM   1892  C CA  . TRP A 1 276 ? 195.472 228.183 131.330 1.00 52.02  ? 308  TRP B CA  1 
ATOM   1893  C C   . TRP A 1 276 ? 196.729 227.609 130.755 1.00 52.02  ? 308  TRP B C   1 
ATOM   1894  O O   . TRP A 1 276 ? 197.755 228.278 130.700 1.00 52.02  ? 308  TRP B O   1 
ATOM   1895  C CB  . TRP A 1 276 ? 194.709 228.871 130.233 1.00 69.65  ? 308  TRP B CB  1 
ATOM   1896  C CG  . TRP A 1 276 ? 193.351 229.282 130.642 1.00 69.65  ? 308  TRP B CG  1 
ATOM   1897  C CD1 . TRP A 1 276 ? 193.027 230.436 131.252 1.00 69.65  ? 308  TRP B CD1 1 
ATOM   1898  C CD2 . TRP A 1 276 ? 192.142 228.490 130.643 1.00 69.65  ? 308  TRP B CD2 1 
ATOM   1899  N NE1 . TRP A 1 276 ? 191.668 230.491 131.446 1.00 69.65  ? 308  TRP B NE1 1 
ATOM   1900  C CE2 . TRP A 1 276 ? 191.077 229.301 131.126 1.00 69.65  ? 308  TRP B CE2 1 
ATOM   1901  C CE3 . TRP A 1 276 ? 191.838 227.162 130.310 1.00 69.65  ? 308  TRP B CE3 1 
ATOM   1902  C CZ2 . TRP A 1 276 ? 189.768 228.830 131.244 1.00 69.65  ? 308  TRP B CZ2 1 
ATOM   1903  C CZ3 . TRP A 1 276 ? 190.537 226.661 130.484 1.00 69.65  ? 308  TRP B CZ3 1 
ATOM   1904  C CH2 . TRP A 1 276 ? 189.510 227.490 130.953 1.00 69.65  ? 308  TRP B CH2 1 
ATOM   1905  N N   . MET A 1 277 ? 196.647 226.374 130.313 1.00 27.45  ? 309  MET B N   1 
ATOM   1906  C CA  . MET A 1 277 ? 197.805 225.686 129.797 1.00 27.45  ? 309  MET B CA  1 
ATOM   1907  C C   . MET A 1 277 ? 197.479 224.688 128.698 1.00 27.45  ? 309  MET B C   1 
ATOM   1908  O O   . MET A 1 277 ? 196.371 224.165 128.619 1.00 27.45  ? 309  MET B O   1 
ATOM   1909  C CB  . MET A 1 277 ? 198.513 224.957 130.927 1.00 38.19  ? 309  MET B CB  1 
ATOM   1910  C CG  . MET A 1 277 ? 199.111 225.890 131.960 1.00 38.19  ? 309  MET B CG  1 
ATOM   1911  S SD  . MET A 1 277 ? 200.123 224.928 133.072 1.00 38.19  ? 309  MET B SD  1 
ATOM   1912  C CE  . MET A 1 277 ? 201.642 224.757 132.122 1.00 38.19  ? 309  MET B CE  1 
ATOM   1913  N N   . GLY A 1 278 ? 198.476 224.386 127.874 1.00 17.64  ? 310  GLY B N   1 
ATOM   1914  C CA  . GLY A 1 278 ? 198.343 223.504 126.727 1.00 17.64  ? 310  GLY B CA  1 
ATOM   1915  C C   . GLY A 1 278 ? 199.523 222.568 126.573 1.00 17.64  ? 310  GLY B C   1 
ATOM   1916  O O   . GLY A 1 278 ? 200.680 222.978 126.642 1.00 17.64  ? 310  GLY B O   1 
ATOM   1917  N N   . SER A 1 279 ? 199.249 221.307 126.296 1.00 21.20  ? 311  SER B N   1 
ATOM   1918  C CA  . SER A 1 279 ? 200.207 220.494 125.554 1.00 21.20  ? 311  SER B CA  1 
ATOM   1919  C C   . SER A 1 279 ? 200.352 221.018 124.115 1.00 21.20  ? 311  SER B C   1 
ATOM   1920  O O   . SER A 1 279 ? 199.721 221.992 123.714 1.00 21.20  ? 311  SER B O   1 
ATOM   1921  C CB  . SER A 1 279 ? 199.709 219.048 125.539 1.00 28.24  ? 311  SER B CB  1 
ATOM   1922  O OG  . SER A 1 279 ? 198.499 218.961 124.816 1.00 28.24  ? 311  SER B OG  1 
ATOM   1923  N N   . ASP A 1 280 ? 201.114 220.308 123.299 1.00 24.98  ? 312  ASP B N   1 
ATOM   1924  C CA  . ASP A 1 280 ? 201.302 220.608 121.889 1.00 24.98  ? 312  ASP B CA  1 
ATOM   1925  C C   . ASP A 1 280 ? 200.033 220.977 121.118 1.00 24.98  ? 312  ASP B C   1 
ATOM   1926  O O   . ASP A 1 280 ? 200.127 221.705 120.143 1.00 24.98  ? 312  ASP B O   1 
ATOM   1927  C CB  . ASP A 1 280 ? 201.944 219.367 121.298 1.00 31.81  ? 312  ASP B CB  1 
ATOM   1928  C CG  . ASP A 1 280 ? 201.998 219.414 119.784 1.00 31.81  ? 312  ASP B CG  1 
ATOM   1929  O OD1 . ASP A 1 280 ? 200.994 219.069 119.124 1.00 31.81  ? 312  ASP B OD1 1 
ATOM   1930  O OD2 . ASP A 1 280 ? 203.063 219.724 119.229 1.00 31.81  ? 312  ASP B OD2 1 
ATOM   1931  N N   . SER A 1 281 ? 198.845 220.543 121.538 1.00 24.50  ? 313  SER B N   1 
ATOM   1932  C CA  . SER A 1 281 ? 197.598 220.804 120.819 1.00 24.50  ? 313  SER B CA  1 
ATOM   1933  C C   . SER A 1 281 ? 197.365 222.257 120.491 1.00 24.50  ? 313  SER B C   1 
ATOM   1934  O O   . SER A 1 281 ? 196.670 222.547 119.520 1.00 24.50  ? 313  SER B O   1 
ATOM   1935  C CB  . SER A 1 281 ? 196.376 220.441 121.643 1.00 32.63  ? 313  SER B CB  1 
ATOM   1936  O OG  . SER A 1 281 ? 196.318 219.069 121.890 1.00 32.63  ? 313  SER B OG  1 
ATOM   1937  N N   . TRP A 1 282 ? 197.905 223.159 121.309 1.00 21.15  ? 314  TRP B N   1 
ATOM   1938  C CA  . TRP A 1 282 ? 197.892 224.574 121.006 1.00 21.15  ? 314  TRP B CA  1 
ATOM   1939  C C   . TRP A 1 282 ? 199.073 225.327 121.609 1.00 21.15  ? 314  TRP B C   1 
ATOM   1940  O O   . TRP A 1 282 ? 199.668 224.946 122.612 1.00 21.15  ? 314  TRP B O   1 
ATOM   1941  C CB  . TRP A 1 282 ? 196.568 225.166 121.448 1.00 28.32  ? 314  TRP B CB  1 
ATOM   1942  C CG  . TRP A 1 282 ? 196.500 225.599 122.863 1.00 28.32  ? 314  TRP B CG  1 
ATOM   1943  C CD1 . TRP A 1 282 ? 196.247 224.806 123.917 1.00 28.32  ? 314  TRP B CD1 1 
ATOM   1944  C CD2 . TRP A 1 282 ? 196.607 226.946 123.390 1.00 28.32  ? 314  TRP B CD2 1 
ATOM   1945  N NE1 . TRP A 1 282 ? 196.088 225.583 125.042 1.00 28.32  ? 314  TRP B NE1 1 
ATOM   1946  C CE2 . TRP A 1 282 ? 196.254 226.914 124.763 1.00 28.32  ? 314  TRP B CE2 1 
ATOM   1947  C CE3 . TRP A 1 282 ? 196.906 228.201 122.831 1.00 28.32  ? 314  TRP B CE3 1 
ATOM   1948  C CZ2 . TRP A 1 282 ? 196.143 228.065 125.535 1.00 28.32  ? 314  TRP B CZ2 1 
ATOM   1949  C CZ3 . TRP A 1 282 ? 196.822 229.365 123.607 1.00 28.32  ? 314  TRP B CZ3 1 
ATOM   1950  C CH2 . TRP A 1 282 ? 196.426 229.302 124.948 1.00 28.32  ? 314  TRP B CH2 1 
ATOM   1951  N N   . GLY A 1 283 ? 199.403 226.438 120.971 1.00 20.70  ? 315  GLY B N   1 
ATOM   1952  C CA  . GLY A 1 283 ? 200.566 227.249 121.277 1.00 20.70  ? 315  GLY B CA  1 
ATOM   1953  C C   . GLY A 1 283 ? 200.681 228.332 120.232 1.00 20.70  ? 315  GLY B C   1 
ATOM   1954  O O   . GLY A 1 283 ? 199.721 229.053 120.026 1.00 20.70  ? 315  GLY B O   1 
ATOM   1955  N N   . SER A 1 284 ? 201.803 228.393 119.521 1.00 25.15  ? 316  SER B N   1 
ATOM   1956  C CA  . SER A 1 284 ? 202.131 229.485 118.604 1.00 25.15  ? 316  SER B CA  1 
ATOM   1957  C C   . SER A 1 284 ? 201.064 229.793 117.552 1.00 25.15  ? 316  SER B C   1 
ATOM   1958  O O   . SER A 1 284 ? 201.031 230.897 117.015 1.00 25.15  ? 316  SER B O   1 
ATOM   1959  C CB  . SER A 1 284 ? 203.473 229.212 117.941 1.00 33.50  ? 316  SER B CB  1 
ATOM   1960  O OG  . SER A 1 284 ? 203.402 228.025 117.190 1.00 33.50  ? 316  SER B OG  1 
ATOM   1961  N N   . LYS A 1 285 ? 200.139 228.864 117.321 1.00 20.81  ? 317  LYS B N   1 
ATOM   1962  C CA  . LYS A 1 285 ? 198.837 229.104 116.697 1.00 20.81  ? 317  LYS B CA  1 
ATOM   1963  C C   . LYS A 1 285 ? 198.168 230.369 117.243 1.00 20.81  ? 317  LYS B C   1 
ATOM   1964  O O   . LYS A 1 285 ? 197.854 230.444 118.424 1.00 20.81  ? 317  LYS B O   1 
ATOM   1965  C CB  . LYS A 1 285 ? 197.948 227.881 116.975 1.00 29.77  ? 317  LYS B CB  1 
ATOM   1966  C CG  . LYS A 1 285 ? 198.516 226.549 116.445 1.00 29.77  ? 317  LYS B CG  1 
ATOM   1967  C CD  . LYS A 1 285 ? 198.586 226.479 114.904 1.00 29.77  ? 317  LYS B CD  1 
ATOM   1968  C CE  . LYS A 1 285 ? 199.936 225.949 114.389 1.00 29.77  ? 317  LYS B CE  1 
ATOM   1969  N NZ  . LYS A 1 285 ? 200.051 226.061 112.903 1.00 29.77  ? 317  LYS B NZ  1 
ATOM   1970  N N   . ILE A 1 286 ? 197.891 231.347 116.381 1.00 24.14  ? 318  ILE B N   1 
ATOM   1971  C CA  . ILE A 1 286 ? 197.291 232.639 116.770 1.00 24.14  ? 318  ILE B CA  1 
ATOM   1972  C C   . ILE A 1 286 ? 195.767 232.600 116.921 1.00 24.14  ? 318  ILE B C   1 
ATOM   1973  O O   . ILE A 1 286 ? 195.192 233.317 117.738 1.00 24.14  ? 318  ILE B O   1 
ATOM   1974  C CB  . ILE A 1 286 ? 197.724 233.729 115.769 1.00 34.31  ? 318  ILE B CB  1 
ATOM   1975  C CG1 . ILE A 1 286 ? 197.322 235.147 116.206 1.00 34.31  ? 318  ILE B CG1 1 
ATOM   1976  C CG2 . ILE A 1 286 ? 197.143 233.510 114.365 1.00 34.31  ? 318  ILE B CG2 1 
ATOM   1977  C CD1 . ILE A 1 286 ? 198.009 235.579 117.498 1.00 34.31  ? 318  ILE B CD1 1 
ATOM   1978  N N   . ALA A 1 287 ? 195.092 231.743 116.158 1.00 22.94  ? 319  ALA B N   1 
ATOM   1979  C CA  . ALA A 1 287 ? 193.641 231.621 116.187 1.00 22.94  ? 319  ALA B CA  1 
ATOM   1980  C C   . ALA A 1 287 ? 193.056 231.194 117.550 1.00 22.94  ? 319  ALA B C   1 
ATOM   1981  O O   . ALA A 1 287 ? 191.959 231.641 117.887 1.00 22.94  ? 319  ALA B O   1 
ATOM   1982  C CB  . ALA A 1 287 ? 193.241 230.678 115.056 1.00 30.99  ? 319  ALA B CB  1 
ATOM   1983  N N   . PRO A 1 288 ? 193.733 230.384 118.378 1.00 21.95  ? 320  PRO B N   1 
ATOM   1984  C CA  . PRO A 1 288 ? 193.384 230.232 119.783 1.00 21.95  ? 320  PRO B CA  1 
ATOM   1985  C C   . PRO A 1 288 ? 193.105 231.539 120.538 1.00 21.95  ? 320  PRO B C   1 
ATOM   1986  O O   . PRO A 1 288 ? 192.037 231.678 121.127 1.00 21.95  ? 320  PRO B O   1 
ATOM   1987  C CB  . PRO A 1 288 ? 194.583 229.506 120.392 1.00 37.51  ? 320  PRO B CB  1 
ATOM   1988  C CG  . PRO A 1 288 ? 195.030 228.597 119.261 1.00 37.51  ? 320  PRO B CG  1 
ATOM   1989  C CD  . PRO A 1 288 ? 194.758 229.423 118.014 1.00 37.51  ? 320  PRO B CD  1 
ATOM   1990  N N   . VAL A 1 289 ? 194.049 232.487 120.544 1.00 22.93  ? 321  VAL B N   1 
ATOM   1991  C CA  . VAL A 1 289 ? 194.072 233.651 121.462 1.00 22.93  ? 321  VAL B CA  1 
ATOM   1992  C C   . VAL A 1 289 ? 193.416 234.920 120.920 1.00 22.93  ? 321  VAL B C   1 
ATOM   1993  O O   . VAL A 1 289 ? 192.982 235.768 121.700 1.00 22.93  ? 321  VAL B O   1 
ATOM   1994  C CB  . VAL A 1 289 ? 195.516 234.005 121.872 1.00 32.29  ? 321  VAL B CB  1 
ATOM   1995  C CG1 . VAL A 1 289 ? 196.067 232.946 122.822 1.00 32.29  ? 321  VAL B CG1 1 
ATOM   1996  C CG2 . VAL A 1 289 ? 196.454 234.166 120.668 1.00 32.29  ? 321  VAL B CG2 1 
ATOM   1997  N N   . LEU A 1 290 ? 193.360 235.082 119.600 1.00 32.27  ? 322  LEU B N   1 
ATOM   1998  C CA  . LEU A 1 290 ? 192.841 236.307 119.011 1.00 32.27  ? 322  LEU B CA  1 
ATOM   1999  C C   . LEU A 1 290 ? 191.373 236.545 119.408 1.00 32.27  ? 322  LEU B C   1 
ATOM   2000  O O   . LEU A 1 290 ? 190.607 235.598 119.585 1.00 32.27  ? 322  LEU B O   1 
ATOM   2001  C CB  . LEU A 1 290 ? 193.052 236.251 117.494 1.00 45.87  ? 322  LEU B CB  1 
ATOM   2002  C CG  . LEU A 1 290 ? 193.290 237.643 116.897 1.00 45.87  ? 322  LEU B CG  1 
ATOM   2003  C CD1 . LEU A 1 290 ? 194.694 238.159 117.215 1.00 45.87  ? 322  LEU B CD1 1 
ATOM   2004  C CD2 . LEU A 1 290 ? 193.196 237.580 115.376 1.00 45.87  ? 322  LEU B CD2 1 
ATOM   2005  N N   . HIS A 1 291 ? 190.971 237.803 119.562 1.00 41.57  ? 323  HIS B N   1 
ATOM   2006  C CA  . HIS A 1 291 ? 189.646 238.262 120.031 1.00 41.57  ? 323  HIS B CA  1 
ATOM   2007  C C   . HIS A 1 291 ? 189.287 237.954 121.502 1.00 41.57  ? 323  HIS B C   1 
ATOM   2008  O O   . HIS A 1 291 ? 188.293 238.446 122.031 1.00 41.57  ? 323  HIS B O   1 
ATOM   2009  C CB  . HIS A 1 291 ? 188.546 237.789 119.065 1.00 55.21  ? 323  HIS B CB  1 
ATOM   2010  C CG  . HIS A 1 291 ? 188.974 237.728 117.617 1.00 55.21  ? 323  HIS B CG  1 
ATOM   2011  N ND1 . HIS A 1 291 ? 189.308 238.819 116.814 1.00 55.21  ? 323  HIS B ND1 1 
ATOM   2012  C CD2 . HIS A 1 291 ? 189.133 236.583 116.891 1.00 55.21  ? 323  HIS B CD2 1 
ATOM   2013  C CE1 . HIS A 1 291 ? 189.649 238.307 115.619 1.00 55.21  ? 323  HIS B CE1 1 
ATOM   2014  N NE2 . HIS A 1 291 ? 189.548 236.968 115.639 1.00 55.21  ? 323  HIS B NE2 1 
ATOM   2015  N N   . LEU A 1 292 ? 190.090 237.140 122.169 1.00 32.11  ? 324  LEU B N   1 
ATOM   2016  C CA  . LEU A 1 292 ? 190.028 236.742 123.542 1.00 32.11  ? 324  LEU B CA  1 
ATOM   2017  C C   . LEU A 1 292 ? 191.403 236.980 124.094 1.00 32.11  ? 324  LEU B C   1 
ATOM   2018  O O   . LEU A 1 292 ? 191.915 236.176 124.863 1.00 32.11  ? 324  LEU B O   1 
ATOM   2019  C CB  . LEU A 1 292 ? 189.726 235.252 123.654 1.00 45.64  ? 324  LEU B CB  1 
ATOM   2020  C CG  . LEU A 1 292 ? 188.366 234.778 123.311 1.00 45.64  ? 324  LEU B CG  1 
ATOM   2021  C CD1 . LEU A 1 292 ? 188.230 234.478 121.830 1.00 45.64  ? 324  LEU B CD1 1 
ATOM   2022  C CD2 . LEU A 1 292 ? 188.109 233.597 124.089 1.00 45.64  ? 324  LEU B CD2 1 
ATOM   2023  N N   . GLU A 1 293 ? 192.126 238.023 123.709 1.00 31.16  ? 325  GLU B N   1 
ATOM   2024  C CA  . GLU A 1 293 ? 193.532 238.083 124.079 1.00 31.16  ? 325  GLU B CA  1 
ATOM   2025  C C   . GLU A 1 293 ? 193.726 238.188 125.601 1.00 31.16  ? 325  GLU B C   1 
ATOM   2026  O O   . GLU A 1 293 ? 194.648 237.589 126.137 1.00 31.16  ? 325  GLU B O   1 
ATOM   2027  C CB  . GLU A 1 293 ? 194.243 239.217 123.336 1.00 41.82  ? 325  GLU B CB  1 
ATOM   2028  C CG  . GLU A 1 293 ? 194.339 238.984 121.819 1.00 41.82  ? 325  GLU B CG  1 
ATOM   2029  C CD  . GLU A 1 293 ? 193.104 239.428 121.009 1.00 41.82  ? 325  GLU B CD  1 
ATOM   2030  O OE1 . GLU A 1 293 ? 192.031 239.709 121.581 1.00 41.82  ? 325  GLU B OE1 1 
ATOM   2031  O OE2 . GLU A 1 293 ? 193.205 239.503 119.765 1.00 41.82  ? 325  GLU B OE2 1 
ATOM   2032  N N   . GLU A 1 294 ? 192.837 238.859 126.334 1.00 30.95  ? 326  GLU B N   1 
ATOM   2033  C CA  . GLU A 1 294 ? 192.975 238.976 127.780 1.00 30.95  ? 326  GLU B CA  1 
ATOM   2034  C C   . GLU A 1 294 ? 192.660 237.687 128.505 1.00 30.95  ? 326  GLU B C   1 
ATOM   2035  O O   . GLU A 1 294 ? 192.909 237.538 129.706 1.00 30.95  ? 326  GLU B O   1 
ATOM   2036  C CB  . GLU A 1 294 ? 192.097 240.098 128.301 1.00 41.54  ? 326  GLU B CB  1 
ATOM   2037  C CG  . GLU A 1 294 ? 192.520 241.462 127.804 1.00 41.54  ? 326  GLU B CG  1 
ATOM   2038  C CD  . GLU A 1 294 ? 192.041 241.735 126.420 1.00 41.54  ? 326  GLU B CD  1 
ATOM   2039  O OE1 . GLU A 1 294 ? 191.322 240.908 125.899 1.00 41.54  ? 326  GLU B OE1 1 
ATOM   2040  O OE2 . GLU A 1 294 ? 192.390 242.748 125.873 1.00 41.54  ? 326  GLU B OE2 1 
ATOM   2041  N N   . VAL A 1 295 ? 192.026 236.776 127.814 1.00 30.13  ? 327  VAL B N   1 
ATOM   2042  C CA  . VAL A 1 295 ? 191.635 235.549 128.417 1.00 30.13  ? 327  VAL B CA  1 
ATOM   2043  C C   . VAL A 1 295 ? 192.873 234.702 128.389 1.00 30.13  ? 327  VAL B C   1 
ATOM   2044  O O   . VAL A 1 295 ? 193.611 234.712 127.414 1.00 30.13  ? 327  VAL B O   1 
ATOM   2045  C CB  . VAL A 1 295 ? 190.467 234.895 127.676 1.00 42.43  ? 327  VAL B CB  1 
ATOM   2046  C CG1 . VAL A 1 295 ? 190.123 233.581 128.307 1.00 42.43  ? 327  VAL B CG1 1 
ATOM   2047  C CG2 . VAL A 1 295 ? 189.273 235.807 127.685 1.00 42.43  ? 327  VAL B CG2 1 
ATOM   2048  N N   . ALA A 1 296 ? 193.163 233.915 129.413 1.00 25.00  ? 328  ALA B N   1 
ATOM   2049  C CA  . ALA A 1 296 ? 194.391 233.115 129.401 1.00 25.00  ? 328  ALA B CA  1 
ATOM   2050  C C   . ALA A 1 296 ? 195.668 233.965 129.345 1.00 25.00  ? 328  ALA B C   1 
ATOM   2051  O O   . ALA A 1 296 ? 196.648 233.622 128.676 1.00 25.00  ? 328  ALA B O   1 
ATOM   2052  C CB  . ALA A 1 296 ? 194.277 231.998 128.344 1.00 33.77  ? 328  ALA B CB  1 
ATOM   2053  N N   . GLU A 1 297 ? 195.688 235.069 130.099 1.00 23.89  ? 329  GLU B N   1 
ATOM   2054  C CA  . GLU A 1 297 ? 196.921 235.829 130.145 1.00 23.89  ? 329  GLU B CA  1 
ATOM   2055  C C   . GLU A 1 297 ? 198.042 235.021 130.758 1.00 23.89  ? 329  GLU B C   1 
ATOM   2056  O O   . GLU A 1 297 ? 197.827 234.344 131.757 1.00 23.89  ? 329  GLU B O   1 
ATOM   2057  C CB  . GLU A 1 297 ? 196.732 237.061 131.032 1.00 32.06  ? 329  GLU B CB  1 
ATOM   2058  C CG  . GLU A 1 297 ? 198.008 237.887 131.240 1.00 32.06  ? 329  GLU B CG  1 
ATOM   2059  C CD  . GLU A 1 297 ? 197.811 239.115 132.071 1.00 32.06  ? 329  GLU B CD  1 
ATOM   2060  O OE1 . GLU A 1 297 ? 196.708 239.383 132.478 1.00 32.06  ? 329  GLU B OE1 1 
ATOM   2061  O OE2 . GLU A 1 297 ? 198.781 239.798 132.292 1.00 32.06  ? 329  GLU B OE2 1 
ATOM   2062  N N   . GLY A 1 298 ? 199.219 235.029 130.130 1.00 25.82  ? 330  GLY B N   1 
ATOM   2063  C CA  . GLY A 1 298 ? 200.404 234.376 130.660 1.00 25.82  ? 330  GLY B CA  1 
ATOM   2064  C C   . GLY A 1 298 ? 200.356 232.880 130.546 1.00 25.82  ? 330  GLY B C   1 
ATOM   2065  O O   . GLY A 1 298 ? 201.188 232.183 131.122 1.00 25.82  ? 330  GLY B O   1 
ATOM   2066  N N   . ALA A 1 299 ? 199.311 232.382 129.893 1.00 22.83  ? 331  ALA B N   1 
ATOM   2067  C CA  . ALA A 1 299 ? 199.077 230.974 129.773 1.00 22.83  ? 331  ALA B CA  1 
ATOM   2068  C C   . ALA A 1 299 ? 200.331 230.316 129.231 1.00 22.83  ? 331  ALA B C   1 
ATOM   2069  O O   . ALA A 1 299 ? 201.011 230.884 128.375 1.00 22.83  ? 331  ALA B O   1 
ATOM   2070  C CB  . ALA A 1 299 ? 197.881 230.772 128.864 1.00 30.84  ? 331  ALA B CB  1 
ATOM   2071  N N   . VAL A 1 300 ? 200.656 229.146 129.759 1.00 22.48  ? 332  VAL B N   1 
ATOM   2072  C CA  . VAL A 1 300 ? 201.869 228.448 129.375 1.00 22.48  ? 332  VAL B CA  1 
ATOM   2073  C C   . VAL A 1 300 ? 201.496 227.233 128.587 1.00 22.48  ? 332  VAL B C   1 
ATOM   2074  O O   . VAL A 1 300 ? 200.734 226.403 129.072 1.00 22.48  ? 332  VAL B O   1 
ATOM   2075  C CB  . VAL A 1 300 ? 202.731 228.112 130.579 1.00 31.66  ? 332  VAL B CB  1 
ATOM   2076  C CG1 . VAL A 1 300 ? 203.932 227.235 130.218 1.00 31.66  ? 332  VAL B CG1 1 
ATOM   2077  C CG2 . VAL A 1 300 ? 203.192 229.429 131.185 1.00 31.66  ? 332  VAL B CG2 1 
ATOM   2078  N N   . THR A 1 301 ? 202.067 227.078 127.404 1.00 18.57  ? 333  THR B N   1 
ATOM   2079  C CA  . THR A 1 301 ? 201.856 225.871 126.625 1.00 18.57  ? 333  THR B CA  1 
ATOM   2080  C C   . THR A 1 301 ? 203.174 225.327 126.156 1.00 18.57  ? 333  THR B C   1 
ATOM   2081  O O   . THR A 1 301 ? 204.194 226.007 126.196 1.00 18.57  ? 333  THR B O   1 
ATOM   2082  C CB  . THR A 1 301 ? 200.841 226.023 125.485 1.00 25.42  ? 333  THR B CB  1 
ATOM   2083  O OG1 . THR A 1 301 ? 201.221 227.012 124.582 1.00 25.42  ? 333  THR B OG1 1 
ATOM   2084  C CG2 . THR A 1 301 ? 199.411 226.335 125.907 1.00 25.42  ? 333  THR B CG2 1 
ATOM   2085  N N   . ILE A 1 302 ? 203.175 224.063 125.783 1.00 20.87  ? 334  ILE B N   1 
ATOM   2086  C CA  . ILE A 1 302 ? 204.349 223.375 125.274 1.00 20.87  ? 334  ILE B CA  1 
ATOM   2087  C C   . ILE A 1 302 ? 204.265 223.275 123.761 1.00 20.87  ? 334  ILE B C   1 
ATOM   2088  O O   . ILE A 1 302 ? 203.212 222.959 123.225 1.00 20.87  ? 334  ILE B O   1 
ATOM   2089  C CB  . ILE A 1 302 ? 204.451 222.000 125.951 1.00 29.66  ? 334  ILE B CB  1 
ATOM   2090  C CG1 . ILE A 1 302 ? 205.107 222.208 127.324 1.00 29.66  ? 334  ILE B CG1 1 
ATOM   2091  C CG2 . ILE A 1 302 ? 205.205 220.969 125.087 1.00 29.66  ? 334  ILE B CG2 1 
ATOM   2092  C CD1 . ILE A 1 302 ? 204.882 221.039 128.289 1.00 29.66  ? 334  ILE B CD1 1 
ATOM   2093  N N   . LEU A 1 303 ? 205.397 223.460 123.083 1.00 29.85  ? 335  LEU B N   1 
ATOM   2094  C CA  . LEU A 1 303 ? 205.595 222.935 121.742 1.00 29.85  ? 335  LEU B CA  1 
ATOM   2095  C C   . LEU A 1 303 ? 206.855 222.085 121.743 1.00 29.85  ? 335  LEU B C   1 
ATOM   2096  O O   . LEU A 1 303 ? 207.863 222.515 122.296 1.00 29.85  ? 335  LEU B O   1 
ATOM   2097  C CB  . LEU A 1 303 ? 205.769 224.045 120.703 1.00 42.43  ? 335  LEU B CB  1 
ATOM   2098  C CG  . LEU A 1 303 ? 204.608 225.039 120.601 1.00 42.43  ? 335  LEU B CG  1 
ATOM   2099  C CD1 . LEU A 1 303 ? 204.945 226.123 119.580 1.00 42.43  ? 335  LEU B CD1 1 
ATOM   2100  C CD2 . LEU A 1 303 ? 203.334 224.359 120.120 1.00 42.43  ? 335  LEU B CD2 1 
ATOM   2101  N N   . PRO A 1 304 ? 206.852 220.931 121.082 1.00 52.02  ? 336  PRO B N   1 
ATOM   2102  C CA  . PRO A 1 304 ? 208.045 220.242 120.620 1.00 52.02  ? 336  PRO B CA  1 
ATOM   2103  C C   . PRO A 1 304 ? 209.089 221.203 120.079 1.00 52.02  ? 336  PRO B C   1 
ATOM   2104  O O   . PRO A 1 304 ? 208.729 222.183 119.436 1.00 52.02  ? 336  PRO B O   1 
ATOM   2105  C CB  . PRO A 1 304 ? 207.549 219.298 119.542 1.00 88.89  ? 336  PRO B CB  1 
ATOM   2106  C CG  . PRO A 1 304 ? 206.172 218.930 120.070 1.00 88.89  ? 336  PRO B CG  1 
ATOM   2107  C CD  . PRO A 1 304 ? 205.675 220.258 120.611 1.00 88.89  ? 336  PRO B CD  1 
ATOM   2108  N N   . LYS A 1 305 ? 210.376 220.957 120.343 1.00 28.57  ? 337  LYS B N   1 
ATOM   2109  C CA  . LYS A 1 305 ? 211.412 221.970 120.105 1.00 28.57  ? 337  LYS B CA  1 
ATOM   2110  C C   . LYS A 1 305 ? 211.512 222.249 118.608 1.00 28.57  ? 337  LYS B C   1 
ATOM   2111  O O   . LYS A 1 305 ? 211.897 221.359 117.853 1.00 28.57  ? 337  LYS B O   1 
ATOM   2112  C CB  . LYS A 1 305 ? 212.753 221.531 120.712 1.00 40.87  ? 337  LYS B CB  1 
ATOM   2113  C CG  . LYS A 1 305 ? 213.780 222.653 120.556 1.00 40.87  ? 337  LYS B CG  1 
ATOM   2114  C CD  . LYS A 1 305 ? 214.909 222.552 121.586 1.00 40.87  ? 337  LYS B CD  1 
ATOM   2115  C CE  . LYS A 1 305 ? 215.831 223.775 121.515 1.00 40.87  ? 337  LYS B CE  1 
ATOM   2116  N NZ  . LYS A 1 305 ? 215.197 224.991 122.081 1.00 40.87  ? 337  LYS B NZ  1 
ATOM   2117  N N   . ARG A 1 306 ? 211.181 223.472 118.194 1.00 23.77  ? 338  ARG B N   1 
ATOM   2118  C CA  . ARG A 1 306 ? 210.908 223.822 116.795 1.00 23.77  ? 338  ARG B CA  1 
ATOM   2119  C C   . ARG A 1 306 ? 211.605 225.097 116.345 1.00 23.77  ? 338  ARG B C   1 
ATOM   2120  O O   . ARG A 1 306 ? 211.643 226.075 117.092 1.00 23.77  ? 338  ARG B O   1 
ATOM   2121  C CB  . ARG A 1 306 ? 209.387 223.819 116.545 1.00 33.38  ? 338  ARG B CB  1 
ATOM   2122  C CG  . ARG A 1 306 ? 208.915 224.144 115.112 1.00 33.38  ? 338  ARG B CG  1 
ATOM   2123  C CD  . ARG A 1 306 ? 207.410 224.049 114.937 1.00 33.38  ? 338  ARG B CD  1 
ATOM   2124  N NE  . ARG A 1 306 ? 206.713 225.062 115.739 1.00 33.38  ? 338  ARG B NE  1 
ATOM   2125  C CZ  . ARG A 1 306 ? 206.497 226.319 115.422 1.00 33.38  ? 338  ARG B CZ  1 
ATOM   2126  N NH1 . ARG A 1 306 ? 205.701 227.036 116.153 1.00 33.38  ? 338  ARG B NH1 1 
ATOM   2127  N NH2 . ARG A 1 306 ? 207.049 226.879 114.388 1.00 33.38  ? 338  ARG B NH2 1 
ATOM   2128  N N   . MET A 1 307 ? 212.128 225.091 115.119 1.00 18.51  ? 339  MET B N   1 
ATOM   2129  C CA  . MET A 1 307 ? 212.767 226.222 114.466 1.00 18.51  ? 339  MET B CA  1 
ATOM   2130  C C   . MET A 1 307 ? 212.056 226.491 113.162 1.00 18.51  ? 339  MET B C   1 
ATOM   2131  O O   . MET A 1 307 ? 211.525 225.571 112.548 1.00 18.51  ? 339  MET B O   1 
ATOM   2132  C CB  . MET A 1 307 ? 214.241 225.948 114.222 1.00 26.45  ? 339  MET B CB  1 
ATOM   2133  C CG  . MET A 1 307 ? 215.054 225.793 115.491 1.00 26.45  ? 339  MET B CG  1 
ATOM   2134  S SD  . MET A 1 307 ? 216.790 225.431 115.203 1.00 26.45  ? 339  MET B SD  1 
ATOM   2135  C CE  . MET A 1 307 ? 216.768 223.691 114.839 1.00 26.45  ? 339  MET B CE  1 
ATOM   2136  N N   . SER A 1 308 ? 212.028 227.742 112.733 1.00 27.57  ? 340  SER B N   1 
ATOM   2137  C CA  . SER A 1 308 ? 211.418 228.056 111.458 1.00 27.57  ? 340  SER B CA  1 
ATOM   2138  C C   . SER A 1 308 ? 212.295 227.601 110.309 1.00 27.57  ? 340  SER B C   1 
ATOM   2139  O O   . SER A 1 308 ? 213.499 227.373 110.462 1.00 27.57  ? 340  SER B O   1 
ATOM   2140  C CB  . SER A 1 308 ? 211.172 229.542 111.357 1.00 36.72  ? 340  SER B CB  1 
ATOM   2141  O OG  . SER A 1 308 ? 212.379 230.248 111.332 1.00 36.72  ? 340  SER B OG  1 
ATOM   2142  N N   . VAL A 1 309 ? 211.694 227.479 109.138 1.00 27.91  ? 341  VAL B N   1 
ATOM   2143  C CA  . VAL A 1 309 ? 212.449 227.105 107.964 1.00 27.91  ? 341  VAL B CA  1 
ATOM   2144  C C   . VAL A 1 309 ? 212.495 228.251 107.006 1.00 27.91  ? 341  VAL B C   1 
ATOM   2145  O O   . VAL A 1 309 ? 211.598 228.413 106.183 1.00 27.91  ? 341  VAL B O   1 
ATOM   2146  C CB  . VAL A 1 309 ? 211.808 225.881 107.302 1.00 39.30  ? 341  VAL B CB  1 
ATOM   2147  C CG1 . VAL A 1 309 ? 212.571 225.505 106.059 1.00 39.30  ? 341  VAL B CG1 1 
ATOM   2148  C CG2 . VAL A 1 309 ? 211.823 224.707 108.311 1.00 39.30  ? 341  VAL B CG2 1 
ATOM   2149  N N   . ARG A 1 310 ? 213.610 228.956 106.995 1.00 31.05  ? 342  ARG B N   1 
ATOM   2150  C CA  . ARG A 1 310 ? 213.690 230.190 106.238 1.00 31.05  ? 342  ARG B CA  1 
ATOM   2151  C C   . ARG A 1 310 ? 213.467 229.998 104.753 1.00 31.05  ? 342  ARG B C   1 
ATOM   2152  O O   . ARG A 1 310 ? 212.811 230.818 104.110 1.00 31.05  ? 342  ARG B O   1 
ATOM   2153  C CB  . ARG A 1 310 ? 215.033 230.829 106.492 1.00 43.61  ? 342  ARG B CB  1 
ATOM   2154  C CG  . ARG A 1 310 ? 215.163 231.382 107.901 1.00 43.61  ? 342  ARG B CG  1 
ATOM   2155  C CD  . ARG A 1 310 ? 216.357 232.234 108.079 1.00 43.61  ? 342  ARG B CD  1 
ATOM   2156  N NE  . ARG A 1 310 ? 217.596 231.472 107.904 1.00 43.61  ? 342  ARG B NE  1 
ATOM   2157  C CZ  . ARG A 1 310 ? 218.223 230.755 108.871 1.00 43.61  ? 342  ARG B CZ  1 
ATOM   2158  N NH1 . ARG A 1 310 ? 219.349 230.123 108.582 1.00 43.61  ? 342  ARG B NH1 1 
ATOM   2159  N NH2 . ARG A 1 310 ? 217.723 230.676 110.092 1.00 43.61  ? 342  ARG B NH2 1 
ATOM   2160  N N   . GLY A 1 311 ? 213.979 228.905 104.198 1.00 30.94  ? 343  GLY B N   1 
ATOM   2161  C CA  . GLY A 1 311 ? 213.812 228.667 102.777 1.00 30.94  ? 343  GLY B CA  1 
ATOM   2162  C C   . GLY A 1 311 ? 212.341 228.551 102.399 1.00 30.94  ? 343  GLY B C   1 
ATOM   2163  O O   . GLY A 1 311 ? 211.944 228.974 101.308 1.00 30.94  ? 343  GLY B O   1 
ATOM   2164  N N   . PHE A 1 312 ? 211.532 227.978 103.289 1.00 52.02  ? 344  PHE B N   1 
ATOM   2165  C CA  . PHE A 1 312 ? 210.128 227.797 103.026 1.00 52.02  ? 344  PHE B CA  1 
ATOM   2166  C C   . PHE A 1 312 ? 209.399 229.054 103.324 1.00 52.02  ? 344  PHE B C   1 
ATOM   2167  O O   . PHE A 1 312 ? 208.535 229.482 102.573 1.00 52.02  ? 344  PHE B O   1 
ATOM   2168  C CB  . PHE A 1 312 ? 209.504 226.683 103.827 1.00 70.35  ? 344  PHE B CB  1 
ATOM   2169  C CG  . PHE A 1 312 ? 208.063 226.580 103.511 1.00 70.35  ? 344  PHE B CG  1 
ATOM   2170  C CD1 . PHE A 1 312 ? 207.639 226.149 102.271 1.00 70.35  ? 344  PHE B CD1 1 
ATOM   2171  C CD2 . PHE A 1 312 ? 207.118 226.924 104.448 1.00 70.35  ? 344  PHE B CD2 1 
ATOM   2172  C CE1 . PHE A 1 312 ? 206.313 226.053 101.980 1.00 70.35  ? 344  PHE B CE1 1 
ATOM   2173  C CE2 . PHE A 1 312 ? 205.781 226.820 104.164 1.00 70.35  ? 344  PHE B CE2 1 
ATOM   2174  C CZ  . PHE A 1 312 ? 205.381 226.374 102.930 1.00 70.35  ? 344  PHE B CZ  1 
ATOM   2175  N N   . ASP A 1 313 ? 209.748 229.701 104.424 1.00 41.61  ? 345  ASP B N   1 
ATOM   2176  C CA  . ASP A 1 313 ? 209.026 230.886 104.796 1.00 41.61  ? 345  ASP B CA  1 
ATOM   2177  C C   . ASP A 1 313 ? 209.102 231.842 103.622 1.00 41.61  ? 345  ASP B C   1 
ATOM   2178  O O   . ASP A 1 313 ? 208.101 232.457 103.243 1.00 41.61  ? 345  ASP B O   1 
ATOM   2179  C CB  . ASP A 1 313 ? 209.709 231.526 105.994 1.00 52.99  ? 345  ASP B CB  1 
ATOM   2180  C CG  . ASP A 1 313 ? 209.628 230.692 107.253 1.00 52.99  ? 345  ASP B CG  1 
ATOM   2181  O OD1 . ASP A 1 313 ? 208.854 229.740 107.321 1.00 52.99  ? 345  ASP B OD1 1 
ATOM   2182  O OD2 . ASP A 1 313 ? 210.358 231.008 108.158 1.00 52.99  ? 345  ASP B OD2 1 
ATOM   2183  N N   . ARG A 1 314 ? 210.288 231.905 103.005 1.00 35.26  ? 346  ARG B N   1 
ATOM   2184  C CA  . ARG A 1 314 ? 210.542 232.717 101.843 1.00 35.26  ? 346  ARG B CA  1 
ATOM   2185  C C   . ARG A 1 314 ? 209.725 232.266 100.656 1.00 35.26  ? 346  ARG B C   1 
ATOM   2186  O O   . ARG A 1 314 ? 209.018 233.069 100.048 1.00 35.26  ? 346  ARG B O   1 
ATOM   2187  C CB  . ARG A 1 314 ? 211.996 232.589 101.451 1.00 49.52  ? 346  ARG B CB  1 
ATOM   2188  C CG  . ARG A 1 314 ? 212.411 233.355 100.214 1.00 49.52  ? 346  ARG B CG  1 
ATOM   2189  C CD  . ARG A 1 314 ? 213.740 232.902 99.746  1.00 49.52  ? 346  ARG B CD  1 
ATOM   2190  N NE  . ARG A 1 314 ? 213.711 231.471 99.376  1.00 49.52  ? 346  ARG B NE  1 
ATOM   2191  C CZ  . ARG A 1 314 ? 213.209 230.951 98.227  1.00 49.52  ? 346  ARG B CZ  1 
ATOM   2192  N NH1 . ARG A 1 314 ? 213.250 229.641 98.041  1.00 49.52  ? 346  ARG B NH1 1 
ATOM   2193  N NH2 . ARG A 1 314 ? 212.687 231.729 97.295  1.00 49.52  ? 346  ARG B NH2 1 
ATOM   2194  N N   . TYR A 1 315 ? 209.804 230.985 100.328 1.00 40.76  ? 347  TYR B N   1 
ATOM   2195  C CA  . TYR A 1 315 ? 209.105 230.449 99.186  1.00 40.76  ? 347  TYR B CA  1 
ATOM   2196  C C   . TYR A 1 315 ? 207.615 230.671 99.271  1.00 40.76  ? 347  TYR B C   1 
ATOM   2197  O O   . TYR A 1 315 ? 206.974 231.115 98.317  1.00 40.76  ? 347  TYR B O   1 
ATOM   2198  C CB  . TYR A 1 315 ? 209.411 228.979 99.098  1.00 54.71  ? 347  TYR B CB  1 
ATOM   2199  C CG  . TYR A 1 315 ? 208.701 228.290 98.060  1.00 54.71  ? 347  TYR B CG  1 
ATOM   2200  C CD1 . TYR A 1 315 ? 209.108 228.421 96.761  1.00 54.71  ? 347  TYR B CD1 1 
ATOM   2201  C CD2 . TYR A 1 315 ? 207.639 227.482 98.394  1.00 54.71  ? 347  TYR B CD2 1 
ATOM   2202  C CE1 . TYR A 1 315 ? 208.453 227.747 95.779  1.00 54.71  ? 347  TYR B CE1 1 
ATOM   2203  C CE2 . TYR A 1 315 ? 206.989 226.804 97.421  1.00 54.71  ? 347  TYR B CE2 1 
ATOM   2204  C CZ  . TYR A 1 315 ? 207.387 226.930 96.112  1.00 54.71  ? 347  TYR B CZ  1 
ATOM   2205  O OH  . TYR A 1 315 ? 206.726 226.236 95.119  1.00 54.71  ? 347  TYR B OH  1 
ATOM   2206  N N   . PHE A 1 316 ? 207.066 230.326 100.413 1.00 52.02  ? 348  PHE B N   1 
ATOM   2207  C CA  . PHE A 1 316 ? 205.661 230.400 100.693 1.00 52.02  ? 348  PHE B CA  1 
ATOM   2208  C C   . PHE A 1 316 ? 205.192 231.825 100.568 1.00 52.02  ? 348  PHE B C   1 
ATOM   2209  O O   . PHE A 1 316 ? 204.211 232.088 99.879  1.00 52.02  ? 348  PHE B O   1 
ATOM   2210  C CB  . PHE A 1 316 ? 205.429 229.867 102.083 1.00 70.35  ? 348  PHE B CB  1 
ATOM   2211  C CG  . PHE A 1 316 ? 204.031 229.808 102.557 1.00 70.35  ? 348  PHE B CG  1 
ATOM   2212  C CD1 . PHE A 1 316 ? 203.175 228.827 102.130 1.00 70.35  ? 348  PHE B CD1 1 
ATOM   2213  C CD2 . PHE A 1 316 ? 203.589 230.691 103.465 1.00 70.35  ? 348  PHE B CD2 1 
ATOM   2214  C CE1 . PHE A 1 316 ? 201.906 228.746 102.616 1.00 70.35  ? 348  PHE B CE1 1 
ATOM   2215  C CE2 . PHE A 1 316 ? 202.324 230.633 103.962 1.00 70.35  ? 348  PHE B CE2 1 
ATOM   2216  C CZ  . PHE A 1 316 ? 201.482 229.659 103.546 1.00 70.35  ? 348  PHE B CZ  1 
ATOM   2217  N N   . SER A 1 317 ? 205.932 232.751 101.189 1.00 46.47  ? 349  SER B N   1 
ATOM   2218  C CA  . SER A 1 317 ? 205.620 234.163 101.177 1.00 46.47  ? 349  SER B CA  1 
ATOM   2219  C C   . SER A 1 317 ? 205.603 234.701 99.754  1.00 46.47  ? 349  SER B C   1 
ATOM   2220  O O   . SER A 1 317 ? 204.705 235.470 99.374  1.00 46.47  ? 349  SER B O   1 
ATOM   2221  C CB  . SER A 1 317 ? 206.679 234.901 101.969 1.00 61.90  ? 349  SER B CB  1 
ATOM   2222  O OG  . SER A 1 317 ? 206.435 236.262 102.014 1.00 61.90  ? 349  SER B OG  1 
ATOM   2223  N N   . SER A 1 318 ? 206.599 234.280 98.958  1.00 43.60  ? 350  SER B N   1 
ATOM   2224  C CA  . SER A 1 318 ? 206.766 234.719 97.581  1.00 43.60  ? 350  SER B CA  1 
ATOM   2225  C C   . SER A 1 318 ? 206.047 233.916 96.488  1.00 43.60  ? 350  SER B C   1 
ATOM   2226  O O   . SER A 1 318 ? 206.030 234.362 95.339  1.00 43.60  ? 350  SER B O   1 
ATOM   2227  C CB  . SER A 1 318 ? 208.245 234.759 97.229  1.00 58.07  ? 350  SER B CB  1 
ATOM   2228  O OG  . SER A 1 318 ? 208.930 235.749 97.958  1.00 58.07  ? 350  SER B OG  1 
ATOM   2229  N N   . ARG A 1 319 ? 205.464 232.762 96.787  1.00 32.18  ? 351  ARG B N   1 
ATOM   2230  C CA  . ARG A 1 319 ? 204.793 231.973 95.760  1.00 32.18  ? 351  ARG B CA  1 
ATOM   2231  C C   . ARG A 1 319 ? 203.549 232.673 95.203  1.00 32.18  ? 351  ARG B C   1 
ATOM   2232  O O   . ARG A 1 319 ? 202.748 233.216 95.962  1.00 32.18  ? 351  ARG B O   1 
ATOM   2233  C CB  . ARG A 1 319 ? 204.382 230.624 96.351  1.00 45.19  ? 351  ARG B CB  1 
ATOM   2234  C CG  . ARG A 1 319 ? 203.651 229.621 95.430  1.00 45.19  ? 351  ARG B CG  1 
ATOM   2235  C CD  . ARG A 1 319 ? 204.563 228.855 94.527  1.00 45.19  ? 351  ARG B CD  1 
ATOM   2236  N NE  . ARG A 1 319 ? 204.859 229.537 93.266  1.00 45.19  ? 351  ARG B NE  1 
ATOM   2237  C CZ  . ARG A 1 319 ? 205.758 229.101 92.347  1.00 45.19  ? 351  ARG B CZ  1 
ATOM   2238  N NH1 . ARG A 1 319 ? 205.992 229.809 91.247  1.00 45.19  ? 351  ARG B NH1 1 
ATOM   2239  N NH2 . ARG A 1 319 ? 206.419 227.974 92.543  1.00 45.19  ? 351  ARG B NH2 1 
ATOM   2240  N N   . THR A 1 320 ? 203.394 232.637 93.871  1.00 33.77  ? 352  THR B N   1 
ATOM   2241  C CA  . THR A 1 320 ? 202.217 233.162 93.174  1.00 33.77  ? 352  THR B CA  1 
ATOM   2242  C C   . THR A 1 320 ? 201.190 232.087 93.363  1.00 33.77  ? 352  THR B C   1 
ATOM   2243  O O   . THR A 1 320 ? 201.478 230.928 93.076  1.00 33.77  ? 352  THR B O   1 
ATOM   2244  C CB  . THR A 1 320 ? 202.361 233.243 91.649  1.00 46.23  ? 352  THR B CB  1 
ATOM   2245  O OG1 . THR A 1 320 ? 203.498 233.988 91.226  1.00 46.23  ? 352  THR B OG1 1 
ATOM   2246  C CG2 . THR A 1 320 ? 201.132 233.953 91.071  1.00 46.23  ? 352  THR B CG2 1 
ATOM   2247  N N   . LEU A 1 321 ? 199.981 232.414 93.739  1.00 35.27  ? 353  LEU B N   1 
ATOM   2248  C CA  . LEU A 1 321 ? 199.098 231.320 94.027  1.00 35.27  ? 353  LEU B CA  1 
ATOM   2249  C C   . LEU A 1 321 ? 198.543 230.569 92.821  1.00 35.27  ? 353  LEU B C   1 
ATOM   2250  O O   . LEU A 1 321 ? 198.096 229.439 92.964  1.00 35.27  ? 353  LEU B O   1 
ATOM   2251  C CB  . LEU A 1 321 ? 198.009 231.775 94.963  1.00 50.13  ? 353  LEU B CB  1 
ATOM   2252  C CG  . LEU A 1 321 ? 198.436 231.757 96.497  1.00 50.13  ? 353  LEU B CG  1 
ATOM   2253  C CD1 . LEU A 1 321 ? 199.426 232.872 96.835  1.00 50.13  ? 353  LEU B CD1 1 
ATOM   2254  C CD2 . LEU A 1 321 ? 197.277 231.833 97.328  1.00 50.13  ? 353  LEU B CD2 1 
ATOM   2255  N N   . ASP A 1 322 ? 198.576 231.125 91.622  1.00 33.29  ? 354  ASP B N   1 
ATOM   2256  C CA  . ASP A 1 322 ? 198.120 230.347 90.496  1.00 33.29  ? 354  ASP B CA  1 
ATOM   2257  C C   . ASP A 1 322 ? 199.282 229.730 89.715  1.00 33.29  ? 354  ASP B C   1 
ATOM   2258  O O   . ASP A 1 322 ? 199.068 229.177 88.627  1.00 33.29  ? 354  ASP B O   1 
ATOM   2259  C CB  . ASP A 1 322 ? 197.170 231.152 89.627  1.00 42.39  ? 354  ASP B CB  1 
ATOM   2260  C CG  . ASP A 1 322 ? 197.762 232.359 89.175  1.00 42.39  ? 354  ASP B CG  1 
ATOM   2261  O OD1 . ASP A 1 322 ? 198.805 232.686 89.679  1.00 42.39  ? 354  ASP B OD1 1 
ATOM   2262  O OD2 . ASP A 1 322 ? 197.187 233.020 88.350  1.00 42.39  ? 354  ASP B OD2 1 
ATOM   2263  N N   . ASN A 1 323 ? 200.515 229.771 90.277  1.00 29.44  ? 355  ASN B N   1 
ATOM   2264  C CA  . ASN A 1 323 ? 201.658 229.156 89.606  1.00 29.44  ? 355  ASN B CA  1 
ATOM   2265  C C   . ASN A 1 323 ? 202.095 227.890 90.338  1.00 29.44  ? 355  ASN B C   1 
ATOM   2266  O O   . ASN A 1 323 ? 203.189 227.369 90.094  1.00 29.44  ? 355  ASN B O   1 
ATOM   2267  C CB  . ASN A 1 323 ? 202.861 230.074 89.472  1.00 39.16  ? 355  ASN B CB  1 
ATOM   2268  C CG  . ASN A 1 323 ? 202.664 231.287 88.547  1.00 39.16  ? 355  ASN B CG  1 
ATOM   2269  O OD1 . ASN A 1 323 ? 203.095 232.418 88.873  1.00 39.16  ? 355  ASN B OD1 1 
ATOM   2270  N ND2 . ASN A 1 323 ? 202.036 231.081 87.412  1.00 39.16  ? 355  ASN B ND2 1 
ATOM   2271  N N   . ASN A 1 324 ? 201.254 227.404 91.241  1.00 32.23  ? 356  ASN B N   1 
ATOM   2272  C CA  . ASN A 1 324 ? 201.565 226.199 91.999  1.00 32.23  ? 356  ASN B CA  1 
ATOM   2273  C C   . ASN A 1 324 ? 200.937 224.981 91.332  1.00 32.23  ? 356  ASN B C   1 
ATOM   2274  O O   . ASN A 1 324 ? 199.723 224.768 91.405  1.00 32.23  ? 356  ASN B O   1 
ATOM   2275  C CB  . ASN A 1 324 ? 201.113 226.329 93.436  1.00 42.87  ? 356  ASN B CB  1 
ATOM   2276  C CG  . ASN A 1 324 ? 201.552 225.161 94.299  1.00 42.87  ? 356  ASN B CG  1 
ATOM   2277  O OD1 . ASN A 1 324 ? 201.683 224.030 93.837  1.00 42.87  ? 356  ASN B OD1 1 
ATOM   2278  N ND2 . ASN A 1 324 ? 201.812 225.429 95.539  1.00 42.87  ? 356  ASN B ND2 1 
ATOM   2279  N N   . ARG A 1 325 ? 201.753 224.204 90.650  1.00 45.26  ? 357  ARG B N   1 
ATOM   2280  C CA  . ARG A 1 325 ? 201.232 223.071 89.925  1.00 45.26  ? 357  ARG B CA  1 
ATOM   2281  C C   . ARG A 1 325 ? 201.152 221.850 90.820  1.00 45.26  ? 357  ARG B C   1 
ATOM   2282  O O   . ARG A 1 325 ? 201.982 221.652 91.704  1.00 45.26  ? 357  ARG B O   1 
ATOM   2283  C CB  . ARG A 1 325 ? 202.073 222.797 88.689  1.00 63.56  ? 357  ARG B CB  1 
ATOM   2284  C CG  . ARG A 1 325 ? 202.114 223.968 87.653  1.00 63.56  ? 357  ARG B CG  1 
ATOM   2285  C CD  . ARG A 1 325 ? 200.865 224.069 86.789  1.00 63.56  ? 357  ARG B CD  1 
ATOM   2286  N NE  . ARG A 1 325 ? 199.714 224.612 87.522  1.00 63.56  ? 357  ARG B NE  1 
ATOM   2287  C CZ  . ARG A 1 325 ? 199.462 225.924 87.759  1.00 63.56  ? 357  ARG B CZ  1 
ATOM   2288  N NH1 . ARG A 1 325 ? 198.415 226.296 88.460  1.00 63.56  ? 357  ARG B NH1 1 
ATOM   2289  N NH2 . ARG A 1 325 ? 200.239 226.865 87.310  1.00 63.56  ? 357  ARG B NH2 1 
ATOM   2290  N N   . ARG A 1 326 ? 200.169 221.007 90.521  1.00 44.58  ? 358  ARG B N   1 
ATOM   2291  C CA  . ARG A 1 326 ? 199.892 219.764 91.231  1.00 44.58  ? 358  ARG B CA  1 
ATOM   2292  C C   . ARG A 1 326 ? 199.551 220.005 92.697  1.00 44.58  ? 358  ARG B C   1 
ATOM   2293  O O   . ARG A 1 326 ? 199.959 219.252 93.576  1.00 44.58  ? 358  ARG B O   1 
ATOM   2294  C CB  . ARG A 1 326 ? 201.063 218.793 91.154  1.00 62.61  ? 358  ARG B CB  1 
ATOM   2295  C CG  . ARG A 1 326 ? 201.716 218.629 89.770  1.00 62.61  ? 358  ARG B CG  1 
ATOM   2296  C CD  . ARG A 1 326 ? 200.757 218.254 88.675  1.00 62.61  ? 358  ARG B CD  1 
ATOM   2297  N NE  . ARG A 1 326 ? 200.144 216.937 88.857  1.00 62.61  ? 358  ARG B NE  1 
ATOM   2298  C CZ  . ARG A 1 326 ? 199.047 216.497 88.191  1.00 62.61  ? 358  ARG B CZ  1 
ATOM   2299  N NH1 . ARG A 1 326 ? 198.600 215.273 88.407  1.00 62.61  ? 358  ARG B NH1 1 
ATOM   2300  N NH2 . ARG A 1 326 ? 198.425 217.278 87.322  1.00 62.61  ? 358  ARG B NH2 1 
ATOM   2301  N N   . ASN A 1 327 ? 198.770 221.043 92.949  1.00 40.14  ? 359  ASN B N   1 
ATOM   2302  C CA  . ASN A 1 327 ? 198.283 221.326 94.280  1.00 40.14  ? 359  ASN B CA  1 
ATOM   2303  C C   . ASN A 1 327 ? 196.841 221.759 94.095  1.00 40.14  ? 359  ASN B C   1 
ATOM   2304  O O   . ASN A 1 327 ? 196.511 222.922 93.850  1.00 40.14  ? 359  ASN B O   1 
ATOM   2305  C CB  . ASN A 1 327 ? 199.139 222.325 95.015  1.00 53.39  ? 359  ASN B CB  1 
ATOM   2306  C CG  . ASN A 1 327 ? 198.699 222.474 96.457  1.00 53.39  ? 359  ASN B CG  1 
ATOM   2307  O OD1 . ASN A 1 327 ? 197.529 222.230 96.803  1.00 53.39  ? 359  ASN B OD1 1 
ATOM   2308  N ND2 . ASN A 1 327 ? 199.618 222.852 97.309  1.00 53.39  ? 359  ASN B ND2 1 
ATOM   2309  N N   . ILE A 1 328 ? 195.962 220.785 94.200  1.00 34.30  ? 360  ILE B N   1 
ATOM   2310  C CA  . ILE A 1 328 ? 194.557 220.962 93.873  1.00 34.30  ? 360  ILE B CA  1 
ATOM   2311  C C   . ILE A 1 328 ? 193.816 221.893 94.813  1.00 34.30  ? 360  ILE B C   1 
ATOM   2312  O O   . ILE A 1 328 ? 192.782 222.445 94.448  1.00 34.30  ? 360  ILE B O   1 
ATOM   2313  C CB  . ILE A 1 328 ? 193.856 219.591 93.776  1.00 48.75  ? 360  ILE B CB  1 
ATOM   2314  C CG1 . ILE A 1 328 ? 193.858 218.871 95.158  1.00 48.75  ? 360  ILE B CG1 1 
ATOM   2315  C CG2 . ILE A 1 328 ? 194.561 218.746 92.686  1.00 48.75  ? 360  ILE B CG2 1 
ATOM   2316  C CD1 . ILE A 1 328 ? 193.059 217.581 95.212  1.00 48.75  ? 360  ILE B CD1 1 
ATOM   2317  N N   . TRP A 1 329 ? 194.311 222.067 96.031  1.00 33.87  ? 361  TRP B N   1 
ATOM   2318  C CA  . TRP A 1 329 ? 193.696 222.958 97.003  1.00 33.87  ? 361  TRP B CA  1 
ATOM   2319  C C   . TRP A 1 329 ? 194.333 224.337 96.993  1.00 33.87  ? 361  TRP B C   1 
ATOM   2320  O O   . TRP A 1 329 ? 193.946 225.205 97.770  1.00 33.87  ? 361  TRP B O   1 
ATOM   2321  C CB  . TRP A 1 329 ? 193.786 222.353 98.400  1.00 45.35  ? 361  TRP B CB  1 
ATOM   2322  C CG  . TRP A 1 329 ? 193.271 220.961 98.522  1.00 45.35  ? 361  TRP B CG  1 
ATOM   2323  C CD1 . TRP A 1 329 ? 191.971 220.605 98.509  1.00 45.35  ? 361  TRP B CD1 1 
ATOM   2324  C CD2 . TRP A 1 329 ? 194.028 219.731 98.666  1.00 45.35  ? 361  TRP B CD2 1 
ATOM   2325  N NE1 . TRP A 1 329 ? 191.868 219.240 98.641  1.00 45.35  ? 361  TRP B NE1 1 
ATOM   2326  C CE2 . TRP A 1 329 ? 193.105 218.651 98.726  1.00 45.35  ? 361  TRP B CE2 1 
ATOM   2327  C CE3 . TRP A 1 329 ? 195.395 219.421 98.761  1.00 45.35  ? 361  TRP B CE3 1 
ATOM   2328  C CZ2 . TRP A 1 329 ? 193.520 217.329 98.839  1.00 45.35  ? 361  TRP B CZ2 1 
ATOM   2329  C CZ3 . TRP A 1 329 ? 195.819 218.090 98.894  1.00 45.35  ? 361  TRP B CZ3 1 
ATOM   2330  C CH2 . TRP A 1 329 ? 194.887 217.050 98.915  1.00 45.35  ? 361  TRP B CH2 1 
ATOM   2331  N N   . PHE A 1 330 ? 195.323 224.606 96.142  1.00 41.41  ? 362  PHE B N   1 
ATOM   2332  C CA  . PHE A 1 330 ? 196.016 225.875 96.306  1.00 41.41  ? 362  PHE B CA  1 
ATOM   2333  C C   . PHE A 1 330 ? 195.110 227.043 95.894  1.00 41.41  ? 362  PHE B C   1 
ATOM   2334  O O   . PHE A 1 330 ? 195.302 228.183 96.321  1.00 41.41  ? 362  PHE B O   1 
ATOM   2335  C CB  . PHE A 1 330 ? 197.323 225.853 95.562  1.00 56.00  ? 362  PHE B CB  1 
ATOM   2336  C CG  . PHE A 1 330 ? 198.410 226.631 96.239  1.00 56.00  ? 362  PHE B CG  1 
ATOM   2337  C CD1 . PHE A 1 330 ? 198.896 226.160 97.449  1.00 56.00  ? 362  PHE B CD1 1 
ATOM   2338  C CD2 . PHE A 1 330 ? 198.995 227.734 95.704  1.00 56.00  ? 362  PHE B CD2 1 
ATOM   2339  C CE1 . PHE A 1 330 ? 199.925 226.778 98.083  1.00 56.00  ? 362  PHE B CE1 1 
ATOM   2340  C CE2 . PHE A 1 330 ? 200.049 228.349 96.350  1.00 56.00  ? 362  PHE B CE2 1 
ATOM   2341  C CZ  . PHE A 1 330 ? 200.501 227.869 97.526  1.00 56.00  ? 362  PHE B CZ  1 
ATOM   2342  N N   . ALA A 1 331 ? 194.106 226.784 95.056  1.00 35.52  ? 363  ALA B N   1 
ATOM   2343  C CA  . ALA A 1 331 ? 193.181 227.848 94.717  1.00 35.52  ? 363  ALA B CA  1 
ATOM   2344  C C   . ALA A 1 331 ? 192.386 228.234 95.960  1.00 35.52  ? 363  ALA B C   1 
ATOM   2345  O O   . ALA A 1 331 ? 192.057 229.408 96.174  1.00 35.52  ? 363  ALA B O   1 
ATOM   2346  C CB  . ALA A 1 331 ? 192.249 227.416 93.607  1.00 47.99  ? 363  ALA B CB  1 
ATOM   2347  N N   . GLU A 1 332 ? 192.086 227.221 96.777  1.00 43.14  ? 364  GLU B N   1 
ATOM   2348  C CA  . GLU A 1 332 ? 191.339 227.397 98.002  1.00 43.14  ? 364  GLU B CA  1 
ATOM   2349  C C   . GLU A 1 332 ? 192.238 228.131 98.971  1.00 43.14  ? 364  GLU B C   1 
ATOM   2350  O O   . GLU A 1 332 ? 191.798 229.027 99.676  1.00 43.14  ? 364  GLU B O   1 
ATOM   2351  C CB  . GLU A 1 332 ? 190.869 226.053 98.525  1.00 56.85  ? 364  GLU B CB  1 
ATOM   2352  C CG  . GLU A 1 332 ? 189.840 225.399 97.610  1.00 56.85  ? 364  GLU B CG  1 
ATOM   2353  C CD  . GLU A 1 332 ? 189.452 224.049 98.056  1.00 56.85  ? 364  GLU B CD  1 
ATOM   2354  O OE1 . GLU A 1 332 ? 190.064 223.578 98.970  1.00 56.85  ? 364  GLU B OE1 1 
ATOM   2355  O OE2 . GLU A 1 332 ? 188.558 223.475 97.485  1.00 56.85  ? 364  GLU B OE2 1 
ATOM   2356  N N   . PHE A 1 333 ? 193.537 227.842 98.915  1.00 52.02  ? 365  PHE B N   1 
ATOM   2357  C CA  . PHE A 1 333 ? 194.490 228.543 99.754  1.00 52.02  ? 365  PHE B CA  1 
ATOM   2358  C C   . PHE A 1 333 ? 194.318 230.021 99.504  1.00 52.02  ? 365  PHE B C   1 
ATOM   2359  O O   . PHE A 1 333 ? 194.132 230.797 100.442 1.00 52.02  ? 365  PHE B O   1 
ATOM   2360  C CB  . PHE A 1 333 ? 195.914 228.073 99.438  1.00 70.35  ? 365  PHE B CB  1 
ATOM   2361  C CG  . PHE A 1 333 ? 197.040 228.777 100.054 1.00 70.35  ? 365  PHE B CG  1 
ATOM   2362  C CD1 . PHE A 1 333 ? 197.245 228.898 101.395 1.00 70.35  ? 365  PHE B CD1 1 
ATOM   2363  C CD2 . PHE A 1 333 ? 197.975 229.264 99.233  1.00 70.35  ? 365  PHE B CD2 1 
ATOM   2364  C CE1 . PHE A 1 333 ? 198.346 229.523 101.854 1.00 70.35  ? 365  PHE B CE1 1 
ATOM   2365  C CE2 . PHE A 1 333 ? 199.082 229.879 99.700  1.00 70.35  ? 365  PHE B CE2 1 
ATOM   2366  C CZ  . PHE A 1 333 ? 199.261 230.004 100.987 1.00 70.35  ? 365  PHE B CZ  1 
ATOM   2367  N N   . TRP A 1 334 ? 194.302 230.442 98.245  1.00 42.87  ? 366  TRP B N   1 
ATOM   2368  C CA  . TRP A 1 334 ? 194.067 231.864 98.038  1.00 42.87  ? 366  TRP B CA  1 
ATOM   2369  C C   . TRP A 1 334 ? 192.749 232.284 98.679  1.00 42.87  ? 366  TRP B C   1 
ATOM   2370  O O   . TRP A 1 334 ? 192.688 233.245 99.448  1.00 42.87  ? 366  TRP B O   1 
ATOM   2371  C CB  . TRP A 1 334 ? 193.988 232.272 96.565  1.00 57.40  ? 366  TRP B CB  1 
ATOM   2372  C CG  . TRP A 1 334 ? 193.741 233.789 96.394  1.00 57.40  ? 366  TRP B CG  1 
ATOM   2373  C CD1 . TRP A 1 334 ? 192.541 234.368 96.513  1.00 57.40  ? 366  TRP B CD1 1 
ATOM   2374  C CD2 . TRP A 1 334 ? 194.652 234.892 96.059  1.00 57.40  ? 366  TRP B CD2 1 
ATOM   2375  N NE1 . TRP A 1 334 ? 192.631 235.697 96.321  1.00 57.40  ? 366  TRP B NE1 1 
ATOM   2376  C CE2 . TRP A 1 334 ? 193.896 236.034 96.047  1.00 57.40  ? 366  TRP B CE2 1 
ATOM   2377  C CE3 . TRP A 1 334 ? 196.011 234.999 95.774  1.00 57.40  ? 366  TRP B CE3 1 
ATOM   2378  C CZ2 . TRP A 1 334 ? 194.437 237.253 95.786  1.00 57.40  ? 366  TRP B CZ2 1 
ATOM   2379  C CZ3 . TRP A 1 334 ? 196.539 236.228 95.497  1.00 57.40  ? 366  TRP B CZ3 1 
ATOM   2380  C CH2 . TRP A 1 334 ? 195.757 237.321 95.511  1.00 57.40  ? 366  TRP B CH2 1 
ATOM   2381  N N   . GLU A 1 335 ? 191.666 231.572 98.367  1.00 40.21  ? 367  GLU B N   1 
ATOM   2382  C CA  . GLU A 1 335 ? 190.365 232.017 98.840  1.00 40.21  ? 367  GLU B CA  1 
ATOM   2383  C C   . GLU A 1 335 ? 190.230 232.177 100.339 1.00 40.21  ? 367  GLU B C   1 
ATOM   2384  O O   . GLU A 1 335 ? 189.661 233.172 100.808 1.00 40.21  ? 367  GLU B O   1 
ATOM   2385  C CB  . GLU A 1 335 ? 189.259 231.104 98.334  1.00 52.99  ? 367  GLU B CB  1 
ATOM   2386  C CG  . GLU A 1 335 ? 187.867 231.579 98.717  1.00 52.99  ? 367  GLU B CG  1 
ATOM   2387  C CD  . GLU A 1 335 ? 186.793 230.780 98.095  1.00 52.99  ? 367  GLU B CD  1 
ATOM   2388  O OE1 . GLU A 1 335 ? 187.085 229.837 97.414  1.00 52.99  ? 367  GLU B OE1 1 
ATOM   2389  O OE2 . GLU A 1 335 ? 185.650 231.127 98.258  1.00 52.99  ? 367  GLU B OE2 1 
ATOM   2390  N N   . ASP A 1 336 ? 190.798 231.259 101.106 1.00 42.14  ? 368  ASP B N   1 
ATOM   2391  C CA  . ASP A 1 336 ? 190.693 231.345 102.554 1.00 42.14  ? 368  ASP B CA  1 
ATOM   2392  C C   . ASP A 1 336 ? 191.730 232.264 103.197 1.00 42.14  ? 368  ASP B C   1 
ATOM   2393  O O   . ASP A 1 336 ? 191.458 232.846 104.247 1.00 42.14  ? 368  ASP B O   1 
ATOM   2394  C CB  . ASP A 1 336 ? 190.791 229.961 103.187 1.00 53.66  ? 368  ASP B CB  1 
ATOM   2395  C CG  . ASP A 1 336 ? 189.600 229.054 102.868 1.00 53.66  ? 368  ASP B CG  1 
ATOM   2396  O OD1 . ASP A 1 336 ? 188.477 229.417 103.157 1.00 53.66  ? 368  ASP B OD1 1 
ATOM   2397  O OD2 . ASP A 1 336 ? 189.831 227.984 102.374 1.00 53.66  ? 368  ASP B OD2 1 
ATOM   2398  N N   . ASN A 1 337 ? 192.918 232.399 102.606 1.00 36.07  ? 369  ASN B N   1 
ATOM   2399  C CA  . ASN A 1 337 ? 193.935 233.254 103.200 1.00 36.07  ? 369  ASN B CA  1 
ATOM   2400  C C   . ASN A 1 337 ? 193.753 234.744 102.842 1.00 36.07  ? 369  ASN B C   1 
ATOM   2401  O O   . ASN A 1 337 ? 194.006 235.613 103.674 1.00 36.07  ? 369  ASN B O   1 
ATOM   2402  C CB  . ASN A 1 337 ? 195.317 232.759 102.798 1.00 47.98  ? 369  ASN B CB  1 
ATOM   2403  C CG  . ASN A 1 337 ? 195.727 231.446 103.455 1.00 47.98  ? 369  ASN B CG  1 
ATOM   2404  O OD1 . ASN A 1 337 ? 195.183 230.386 103.130 1.00 47.98  ? 369  ASN B OD1 1 
ATOM   2405  N ND2 . ASN A 1 337 ? 196.702 231.494 104.347 1.00 47.98  ? 369  ASN B ND2 1 
ATOM   2406  N N   . PHE A 1 338 ? 193.242 235.048 101.643 1.00 45.27  ? 370  PHE B N   1 
ATOM   2407  C CA  . PHE A 1 338 ? 193.052 236.433 101.203 1.00 45.27  ? 370  PHE B CA  1 
ATOM   2408  C C   . PHE A 1 338 ? 191.594 236.890 101.299 1.00 45.27  ? 370  PHE B C   1 
ATOM   2409  O O   . PHE A 1 338 ? 191.265 238.021 100.940 1.00 45.27  ? 370  PHE B O   1 
ATOM   2410  C CB  . PHE A 1 338 ? 193.503 236.574 99.759  1.00 63.14  ? 370  PHE B CB  1 
ATOM   2411  C CG  . PHE A 1 338 ? 194.964 236.387 99.500  1.00 63.14  ? 370  PHE B CG  1 
ATOM   2412  C CD1 . PHE A 1 338 ? 195.499 235.130 99.427  1.00 63.14  ? 370  PHE B CD1 1 
ATOM   2413  C CD2 . PHE A 1 338 ? 195.793 237.463 99.242  1.00 63.14  ? 370  PHE B CD2 1 
ATOM   2414  C CE1 . PHE A 1 338 ? 196.800 234.935 99.114  1.00 63.14  ? 370  PHE B CE1 1 
ATOM   2415  C CE2 . PHE A 1 338 ? 197.108 237.258 98.916  1.00 63.14  ? 370  PHE B CE2 1 
ATOM   2416  C CZ  . PHE A 1 338 ? 197.594 235.988 98.844  1.00 63.14  ? 370  PHE B CZ  1 
ATOM   2417  N N   . HIS A 1 339 ? 190.728 236.003 101.774 1.00 48.52  ? 371  HIS B N   1 
ATOM   2418  C CA  . HIS A 1 339 ? 189.291 236.247 101.959 1.00 48.52  ? 371  HIS B CA  1 
ATOM   2419  C C   . HIS A 1 339 ? 188.579 236.751 100.702 1.00 48.52  ? 371  HIS B C   1 
ATOM   2420  O O   . HIS A 1 339 ? 187.778 237.691 100.749 1.00 48.52  ? 371  HIS B O   1 
ATOM   2421  C CB  . HIS A 1 339 ? 189.132 237.256 103.083 1.00 64.45  ? 371  HIS B CB  1 
ATOM   2422  C CG  . HIS A 1 339 ? 189.861 236.799 104.270 1.00 64.45  ? 371  HIS B CG  1 
ATOM   2423  N ND1 . HIS A 1 339 ? 189.406 235.794 105.088 1.00 64.45  ? 371  HIS B ND1 1 
ATOM   2424  C CD2 . HIS A 1 339 ? 191.068 237.160 104.745 1.00 64.45  ? 371  HIS B CD2 1 
ATOM   2425  C CE1 . HIS A 1 339 ? 190.305 235.566 106.028 1.00 64.45  ? 371  HIS B CE1 1 
ATOM   2426  N NE2 . HIS A 1 339 ? 191.323 236.384 105.837 1.00 64.45  ? 371  HIS B NE2 1 
ATOM   2427  N N   . CYS A 1 340 ? 188.897 236.142 99.573  1.00 46.74  ? 372  CYS B N   1 
ATOM   2428  C CA  . CYS A 1 340 ? 188.334 236.541 98.281  1.00 46.74  ? 372  CYS B CA  1 
ATOM   2429  C C   . CYS A 1 340 ? 188.636 235.540 97.177  1.00 46.74  ? 372  CYS B C   1 
ATOM   2430  O O   . CYS A 1 340 ? 189.547 234.748 97.304  1.00 46.74  ? 372  CYS B O   1 
ATOM   2431  C CB  . CYS A 1 340 ? 188.902 237.887 97.894  1.00 62.26  ? 372  CYS B CB  1 
ATOM   2432  S SG  . CYS A 1 340 ? 190.656 237.881 97.727  1.00 62.26  ? 372  CYS B SG  1 
ATOM   2433  N N   . LYS A 1 341 ? 187.998 235.645 96.018  1.00 37.98  ? 373  LYS B N   1 
ATOM   2434  C CA  . LYS A 1 341 ? 188.372 234.705 94.955  1.00 37.98  ? 373  LYS B CA  1 
ATOM   2435  C C   . LYS A 1 341 ? 189.724 235.052 94.255  1.00 37.98  ? 373  LYS B C   1 
ATOM   2436  O O   . LYS A 1 341 ? 190.051 236.227 94.049  1.00 37.98  ? 373  LYS B O   1 
ATOM   2437  C CB  . LYS A 1 341 ? 187.264 234.630 93.894  1.00 54.33  ? 373  LYS B CB  1 
ATOM   2438  C CG  . LYS A 1 341 ? 185.861 234.179 94.387  1.00 54.33  ? 373  LYS B CG  1 
ATOM   2439  C CD  . LYS A 1 341 ? 185.796 232.763 94.921  1.00 54.33  ? 373  LYS B CD  1 
ATOM   2440  C CE  . LYS A 1 341 ? 184.330 232.382 95.205  1.00 54.33  ? 373  LYS B CE  1 
ATOM   2441  N NZ  . LYS A 1 341 ? 184.193 231.021 95.814  1.00 54.33  ? 373  LYS B NZ  1 
ATOM   2442  N N   . LEU A 1 342 ? 190.482 233.991 93.836  1.00 36.86  ? 374  LEU B N   1 
ATOM   2443  C CA  . LEU A 1 342 ? 191.757 234.065 93.078  1.00 36.86  ? 374  LEU B CA  1 
ATOM   2444  C C   . LEU A 1 342 ? 191.532 234.586 91.651  1.00 36.86  ? 374  LEU B C   1 
ATOM   2445  O O   . LEU A 1 342 ? 190.600 234.180 90.933  1.00 36.86  ? 374  LEU B O   1 
ATOM   2446  C CB  . LEU A 1 342 ? 192.465 232.651 93.069  1.00 52.39  ? 374  LEU B CB  1 
ATOM   2447  C CG  . LEU A 1 342 ? 193.943 232.434 92.300  1.00 52.39  ? 374  LEU B CG  1 
ATOM   2448  C CD1 . LEU A 1 342 ? 195.083 233.303 92.947  1.00 52.39  ? 374  LEU B CD1 1 
ATOM   2449  C CD2 . LEU A 1 342 ? 194.353 230.901 92.432  1.00 52.39  ? 374  LEU B CD2 1 
ATOM   2450  N N   . VAL A 1 353 ? 182.168 238.209 95.314  1.00 62.25  ? 385  VAL B N   1 
ATOM   2451  C CA  . VAL A 1 353 ? 183.229 237.503 94.598  1.00 62.25  ? 385  VAL B CA  1 
ATOM   2452  C C   . VAL A 1 353 ? 184.599 238.104 94.996  1.00 62.25  ? 385  VAL B C   1 
ATOM   2453  O O   . VAL A 1 353 ? 185.485 237.370 95.477  1.00 62.25  ? 385  VAL B O   1 
ATOM   2454  C CB  . VAL A 1 353 ? 182.981 237.546 93.007  1.00 87.66  ? 385  VAL B CB  1 
ATOM   2455  C CG1 . VAL A 1 353 ? 184.190 236.852 92.176  1.00 87.66  ? 385  VAL B CG1 1 
ATOM   2456  C CG2 . VAL A 1 353 ? 181.606 236.804 92.616  1.00 87.66  ? 385  VAL B CG2 1 
ATOM   2457  N N   . LYS A 1 354 ? 184.775 239.447 94.771  1.00 70.64  ? 386  LYS B N   1 
ATOM   2458  C CA  . LYS A 1 354 ? 186.003 240.230 95.028  1.00 70.64  ? 386  LYS B CA  1 
ATOM   2459  C C   . LYS A 1 354 ? 187.203 239.611 94.337  1.00 70.64  ? 386  LYS B C   1 
ATOM   2460  O O   . LYS A 1 354 ? 188.226 239.387 94.970  1.00 70.64  ? 386  LYS B O   1 
ATOM   2461  C CB  . LYS A 1 354 ? 186.318 240.338 96.529  1.00 105.04 ? 386  LYS B CB  1 
ATOM   2462  C CG  . LYS A 1 354 ? 185.266 241.003 97.376  1.00 105.04 ? 386  LYS B CG  1 
ATOM   2463  C CD  . LYS A 1 354 ? 185.747 241.096 98.827  1.00 105.04 ? 386  LYS B CD  1 
ATOM   2464  C CE  . LYS A 1 354 ? 184.696 241.705 99.738  1.00 105.04 ? 386  LYS B CE  1 
ATOM   2465  N NZ  . LYS A 1 354 ? 185.179 241.813 101.151 1.00 105.04 ? 386  LYS B NZ  1 
ATOM   2466  N N   . LYS A 1 355 ? 187.076 239.273 93.064  1.00 65.38  ? 387  LYS B N   1 
ATOM   2467  C CA  . LYS A 1 355 ? 188.208 238.618 92.448  1.00 65.38  ? 387  LYS B CA  1 
ATOM   2468  C C   . LYS A 1 355 ? 189.393 239.550 92.546  1.00 65.38  ? 387  LYS B C   1 
ATOM   2469  O O   . LYS A 1 355 ? 189.319 240.711 92.136  1.00 65.38  ? 387  LYS B O   1 
ATOM   2470  C CB  . LYS A 1 355 ? 187.919 238.255 90.993  1.00 97.22  ? 387  LYS B CB  1 
ATOM   2471  C CG  . LYS A 1 355 ? 189.013 237.445 90.293  1.00 97.22  ? 387  LYS B CG  1 
ATOM   2472  C CD  . LYS A 1 355 ? 188.581 237.112 88.859  1.00 97.22  ? 387  LYS B CD  1 
ATOM   2473  C CE  . LYS A 1 355 ? 189.668 236.391 88.039  1.00 97.22  ? 387  LYS B CE  1 
ATOM   2474  N NZ  . LYS A 1 355 ? 189.820 234.940 88.393  1.00 97.22  ? 387  LYS B NZ  1 
ATOM   2475  N N   . CYS A 1 356 ? 190.486 239.035 93.072  1.00 56.12  ? 388  CYS B N   1 
ATOM   2476  C CA  . CYS A 1 356 ? 191.690 239.817 93.247  1.00 56.12  ? 388  CYS B CA  1 
ATOM   2477  C C   . CYS A 1 356 ? 192.832 239.332 92.398  1.00 56.12  ? 388  CYS B C   1 
ATOM   2478  O O   . CYS A 1 356 ? 192.921 238.153 92.052  1.00 56.12  ? 388  CYS B O   1 
ATOM   2479  C CB  . CYS A 1 356 ? 192.066 239.869 94.709  1.00 74.75  ? 388  CYS B CB  1 
ATOM   2480  S SG  . CYS A 1 356 ? 190.885 240.771 95.707  1.00 74.75  ? 388  CYS B SG  1 
ATOM   2481  N N   . THR A 1 357 ? 193.711 240.257 92.068  1.00 54.21  ? 389  THR B N   1 
ATOM   2482  C CA  . THR A 1 357 ? 194.860 239.978 91.250  1.00 54.21  ? 389  THR B CA  1 
ATOM   2483  C C   . THR A 1 357 ? 195.754 238.939 91.908  1.00 54.21  ? 389  THR B C   1 
ATOM   2484  O O   . THR A 1 357 ? 196.208 239.107 93.039  1.00 54.21  ? 389  THR B O   1 
ATOM   2485  C CB  . THR A 1 357 ? 195.621 241.292 91.012  1.00 74.21  ? 389  THR B CB  1 
ATOM   2486  O OG1 . THR A 1 357 ? 194.732 242.250 90.423  1.00 74.21  ? 389  THR B OG1 1 
ATOM   2487  C CG2 . THR A 1 357 ? 196.762 241.072 90.068  1.00 74.21  ? 389  THR B CG2 1 
ATOM   2488  N N   . ASN A 1 358 ? 196.098 237.923 91.123  1.00 57.32  ? 390  ASN B N   1 
ATOM   2489  C CA  . ASN A 1 358 ? 196.898 236.764 91.513  1.00 57.32  ? 390  ASN B CA  1 
ATOM   2490  C C   . ASN A 1 358 ? 198.342 237.086 91.803  1.00 57.32  ? 390  ASN B C   1 
ATOM   2491  O O   . ASN A 1 358 ? 199.044 236.361 92.505  1.00 57.32  ? 390  ASN B O   1 
ATOM   2492  C CB  . ASN A 1 358 ? 196.856 235.806 90.361  1.00 76.25  ? 390  ASN B CB  1 
ATOM   2493  C CG  . ASN A 1 358 ? 197.406 236.501 89.107  1.00 76.25  ? 390  ASN B CG  1 
ATOM   2494  O OD1 . ASN A 1 358 ? 197.523 237.751 89.064  1.00 76.25  ? 390  ASN B OD1 1 
ATOM   2495  N ND2 . ASN A 1 358 ? 197.738 235.748 88.108  1.00 76.25  ? 390  ASN B ND2 1 
ATOM   2496  N N   . ARG A 1 359 ? 198.756 238.213 91.294  1.00 55.53  ? 391  ARG B N   1 
ATOM   2497  C CA  . ARG A 1 359 ? 200.102 238.688 91.455  1.00 55.53  ? 391  ARG B CA  1 
ATOM   2498  C C   . ARG A 1 359 ? 200.437 238.973 92.906  1.00 55.53  ? 391  ARG B C   1 
ATOM   2499  O O   . ARG A 1 359 ? 201.607 238.865 93.279  1.00 55.53  ? 391  ARG B O   1 
ATOM   2500  C CB  . ARG A 1 359 ? 200.376 239.945 90.650  1.00 77.99  ? 391  ARG B CB  1 
ATOM   2501  C CG  . ARG A 1 359 ? 200.383 239.737 89.148  1.00 77.99  ? 391  ARG B CG  1 
ATOM   2502  C CD  . ARG A 1 359 ? 200.987 240.881 88.398  1.00 77.99  ? 391  ARG B CD  1 
ATOM   2503  N NE  . ARG A 1 359 ? 200.285 242.163 88.577  1.00 77.99  ? 391  ARG B NE  1 
ATOM   2504  C CZ  . ARG A 1 359 ? 199.215 242.598 87.865  1.00 77.99  ? 391  ARG B CZ  1 
ATOM   2505  N NH1 . ARG A 1 359 ? 198.726 243.804 88.106  1.00 77.99  ? 391  ARG B NH1 1 
ATOM   2506  N NH2 . ARG A 1 359 ? 198.654 241.841 86.944  1.00 77.99  ? 391  ARG B NH2 1 
ATOM   2507  N N   . GLU A 1 360 ? 199.458 239.377 93.723  1.00 53.74  ? 392  GLU B N   1 
ATOM   2508  C CA  . GLU A 1 360 ? 199.795 239.717 95.093  1.00 53.74  ? 392  GLU B CA  1 
ATOM   2509  C C   . GLU A 1 360 ? 200.455 238.541 95.775  1.00 53.74  ? 392  GLU B C   1 
ATOM   2510  O O   . GLU A 1 360 ? 199.926 237.429 95.770  1.00 53.74  ? 392  GLU B O   1 
ATOM   2511  C CB  . GLU A 1 360 ? 198.544 240.105 95.857  1.00 70.82  ? 392  GLU B CB  1 
ATOM   2512  C CG  . GLU A 1 360 ? 198.765 240.542 97.262  1.00 70.82  ? 392  GLU B CG  1 
ATOM   2513  C CD  . GLU A 1 360 ? 197.504 240.893 97.925  1.00 70.82  ? 392  GLU B CD  1 
ATOM   2514  O OE1 . GLU A 1 360 ? 196.577 241.265 97.252  1.00 70.82  ? 392  GLU B OE1 1 
ATOM   2515  O OE2 . GLU A 1 360 ? 197.429 240.725 99.104  1.00 70.82  ? 392  GLU B OE2 1 
ATOM   2516  N N   . ARG A 1 361 ? 201.578 238.800 96.428  1.00 54.62  ? 393  ARG B N   1 
ATOM   2517  C CA  . ARG A 1 361 ? 202.285 237.747 97.121  1.00 54.62  ? 393  ARG B CA  1 
ATOM   2518  C C   . ARG A 1 361 ? 201.535 237.506 98.408  1.00 54.62  ? 393  ARG B C   1 
ATOM   2519  O O   . ARG A 1 361 ? 200.983 238.443 98.979  1.00 54.62  ? 393  ARG B O   1 
ATOM   2520  C CB  . ARG A 1 361 ? 203.704 238.160 97.456  1.00 76.71  ? 393  ARG B CB  1 
ATOM   2521  C CG  . ARG A 1 361 ? 204.594 238.579 96.312  1.00 76.71  ? 393  ARG B CG  1 
ATOM   2522  C CD  . ARG A 1 361 ? 204.885 237.494 95.377  1.00 76.71  ? 393  ARG B CD  1 
ATOM   2523  N NE  . ARG A 1 361 ? 203.978 237.471 94.260  1.00 76.71  ? 393  ARG B NE  1 
ATOM   2524  C CZ  . ARG A 1 361 ? 203.969 236.551 93.293  1.00 76.71  ? 393  ARG B CZ  1 
ATOM   2525  N NH1 . ARG A 1 361 ? 203.120 236.696 92.344  1.00 76.71  ? 393  ARG B NH1 1 
ATOM   2526  N NH2 . ARG A 1 361 ? 204.783 235.529 93.267  1.00 76.71  ? 393  ARG B NH2 1 
ATOM   2527  N N   . ILE A 1 362 ? 201.553 236.294 98.942  1.00 52.27  ? 394  ILE B N   1 
ATOM   2528  C CA  . ILE A 1 362 ? 200.862 236.106 100.203 1.00 52.27  ? 394  ILE B CA  1 
ATOM   2529  C C   . ILE A 1 362 ? 201.547 236.914 101.290 1.00 52.27  ? 394  ILE B C   1 
ATOM   2530  O O   . ILE A 1 362 ? 200.885 237.462 102.171 1.00 52.27  ? 394  ILE B O   1 
ATOM   2531  C CB  . ILE A 1 362 ? 200.674 234.613 100.532 1.00 74.29  ? 394  ILE B CB  1 
ATOM   2532  C CG1 . ILE A 1 362 ? 199.616 234.522 101.579 1.00 74.29  ? 394  ILE B CG1 1 
ATOM   2533  C CG2 . ILE A 1 362 ? 201.963 233.939 100.939 1.00 74.29  ? 394  ILE B CG2 1 
ATOM   2534  C CD1 . ILE A 1 362 ? 199.069 233.179 101.836 1.00 74.29  ? 394  ILE B CD1 1 
ATOM   2535  N N   . GLY A 1 363 ? 202.854 237.105 101.146 1.00 51.14  ? 395  GLY B N   1 
ATOM   2536  C CA  . GLY A 1 363 ? 203.670 237.888 102.059 1.00 51.14  ? 395  GLY B CA  1 
ATOM   2537  C C   . GLY A 1 363 ? 203.271 239.367 102.144 1.00 51.14  ? 395  GLY B C   1 
ATOM   2538  O O   . GLY A 1 363 ? 203.792 240.098 102.987 1.00 51.14  ? 395  GLY B O   1 
ATOM   2539  N N   . GLN A 1 364 ? 202.388 239.836 101.258 1.00 52.89  ? 396  GLN B N   1 
ATOM   2540  C CA  . GLN A 1 364 ? 201.933 241.215 101.274 1.00 52.89  ? 396  GLN B CA  1 
ATOM   2541  C C   . GLN A 1 364 ? 200.684 241.451 102.125 1.00 52.89  ? 396  GLN B C   1 
ATOM   2542  O O   . GLN A 1 364 ? 200.234 242.594 102.234 1.00 52.89  ? 396  GLN B O   1 
ATOM   2543  C CB  . GLN A 1 364 ? 201.673 241.714 99.851  1.00 71.89  ? 396  GLN B CB  1 
ATOM   2544  C CG  . GLN A 1 364 ? 202.919 241.850 99.012  1.00 71.89  ? 396  GLN B CG  1 
ATOM   2545  C CD  . GLN A 1 364 ? 202.635 242.305 97.579  1.00 71.89  ? 396  GLN B CD  1 
ATOM   2546  O OE1 . GLN A 1 364 ? 202.348 241.529 96.643  1.00 71.89  ? 396  GLN B OE1 1 
ATOM   2547  N NE2 . GLN A 1 364 ? 202.715 243.618 97.391  1.00 71.89  ? 396  GLN B NE2 1 
ATOM   2548  N N   . ASP A 1 365 ? 200.117 240.403 102.725 1.00 60.52  ? 397  ASP B N   1 
ATOM   2549  C CA  . ASP A 1 365 ? 198.889 240.565 103.511 1.00 60.52  ? 397  ASP B CA  1 
ATOM   2550  C C   . ASP A 1 365 ? 198.850 239.659 104.755 1.00 60.52  ? 397  ASP B C   1 
ATOM   2551  O O   . ASP A 1 365 ? 199.727 238.822 104.964 1.00 60.52  ? 397  ASP B O   1 
ATOM   2552  C CB  . ASP A 1 365 ? 197.671 240.284 102.596 1.00 77.07  ? 397  ASP B CB  1 
ATOM   2553  C CG  . ASP A 1 365 ? 196.341 240.949 103.049 1.00 77.07  ? 397  ASP B CG  1 
ATOM   2554  O OD1 . ASP A 1 365 ? 196.330 241.484 104.137 1.00 77.07  ? 397  ASP B OD1 1 
ATOM   2555  O OD2 . ASP A 1 365 ? 195.368 240.887 102.338 1.00 77.07  ? 397  ASP B OD2 1 
ATOM   2556  N N   . SER A 1 366 ? 197.751 239.756 105.527 1.00 67.55  ? 398  SER B N   1 
ATOM   2557  C CA  . SER A 1 366 ? 197.476 239.002 106.776 1.00 67.55  ? 398  SER B CA  1 
ATOM   2558  C C   . SER A 1 366 ? 197.330 237.514 106.497 1.00 67.55  ? 398  SER B C   1 
ATOM   2559  O O   . SER A 1 366 ? 197.340 236.673 107.396 1.00 67.55  ? 398  SER B O   1 
ATOM   2560  C CB  . SER A 1 366 ? 196.214 239.519 107.437 1.00 89.97  ? 398  SER B CB  1 
ATOM   2561  O OG  . SER A 1 366 ? 195.080 239.208 106.677 1.00 89.97  ? 398  SER B OG  1 
ATOM   2562  N N   . ALA A 1 367 ? 197.221 237.234 105.215 1.00 56.76  ? 399  ALA B N   1 
ATOM   2563  C CA  . ALA A 1 367 ? 197.140 235.952 104.573 1.00 56.76  ? 399  ALA B CA  1 
ATOM   2564  C C   . ALA A 1 367 ? 198.391 235.116 104.924 1.00 56.76  ? 399  ALA B C   1 
ATOM   2565  O O   . ALA A 1 367 ? 198.350 233.879 104.981 1.00 56.76  ? 399  ALA B O   1 
ATOM   2566  C CB  . ALA A 1 367 ? 197.024 236.208 103.069 1.00 76.68  ? 399  ALA B CB  1 
ATOM   2567  N N   . TYR A 1 368 ? 199.531 235.792 105.133 1.00 39.10  ? 400  TYR B N   1 
ATOM   2568  C CA  . TYR A 1 368 ? 200.794 235.127 105.439 1.00 39.10  ? 400  TYR B CA  1 
ATOM   2569  C C   . TYR A 1 368 ? 201.222 235.151 106.895 1.00 39.10  ? 400  TYR B C   1 
ATOM   2570  O O   . TYR A 1 368 ? 201.201 236.190 107.557 1.00 39.10  ? 400  TYR B O   1 
ATOM   2571  C CB  . TYR A 1 368 ? 201.931 235.764 104.659 1.00 52.48  ? 400  TYR B CB  1 
ATOM   2572  C CG  . TYR A 1 368 ? 203.301 235.298 105.074 1.00 52.48  ? 400  TYR B CG  1 
ATOM   2573  C CD1 . TYR A 1 368 ? 203.828 234.124 104.597 1.00 52.48  ? 400  TYR B CD1 1 
ATOM   2574  C CD2 . TYR A 1 368 ? 204.032 236.073 105.964 1.00 52.48  ? 400  TYR B CD2 1 
ATOM   2575  C CE1 . TYR A 1 368 ? 205.092 233.727 105.017 1.00 52.48  ? 400  TYR B CE1 1 
ATOM   2576  C CE2 . TYR A 1 368 ? 205.274 235.672 106.375 1.00 52.48  ? 400  TYR B CE2 1 
ATOM   2577  C CZ  . TYR A 1 368 ? 205.799 234.505 105.902 1.00 52.48  ? 400  TYR B CZ  1 
ATOM   2578  O OH  . TYR A 1 368 ? 207.041 234.103 106.293 1.00 52.48  ? 400  TYR B OH  1 
ATOM   2579  N N   . GLU A 1 369 ? 201.755 234.014 107.366 1.00 32.87  ? 401  GLU B N   1 
ATOM   2580  C CA  . GLU A 1 369 ? 202.706 233.909 108.486 1.00 32.87  ? 401  GLU B CA  1 
ATOM   2581  C C   . GLU A 1 369 ? 203.502 232.572 108.440 1.00 32.87  ? 401  GLU B C   1 
ATOM   2582  O O   . GLU A 1 369 ? 203.076 231.603 107.807 1.00 32.87  ? 401  GLU B O   1 
ATOM   2583  C CB  . GLU A 1 369 ? 201.940 234.087 109.819 1.00 44.11  ? 401  GLU B CB  1 
ATOM   2584  C CG  . GLU A 1 369 ? 202.644 233.742 111.142 1.00 44.11  ? 401  GLU B CG  1 
ATOM   2585  C CD  . GLU A 1 369 ? 203.968 234.475 111.412 1.00 44.11  ? 401  GLU B CD  1 
ATOM   2586  O OE1 . GLU A 1 369 ? 204.645 234.922 110.461 1.00 44.11  ? 401  GLU B OE1 1 
ATOM   2587  O OE2 . GLU A 1 369 ? 204.358 234.572 112.596 1.00 44.11  ? 401  GLU B OE2 1 
ATOM   2588  N N   . GLN A 1 370 ? 204.633 232.500 109.151 1.00 30.08  ? 402  GLN B N   1 
ATOM   2589  C CA  . GLN A 1 370 ? 205.435 231.306 109.469 1.00 30.08  ? 402  GLN B CA  1 
ATOM   2590  C C   . GLN A 1 370 ? 204.588 230.142 110.019 1.00 30.08  ? 402  GLN B C   1 
ATOM   2591  O O   . GLN A 1 370 ? 203.902 230.291 111.029 1.00 30.08  ? 402  GLN B O   1 
ATOM   2592  C CB  . GLN A 1 370 ? 206.489 231.721 110.523 1.00 40.88  ? 402  GLN B CB  1 
ATOM   2593  C CG  . GLN A 1 370 ? 207.529 230.657 110.894 1.00 40.88  ? 402  GLN B CG  1 
ATOM   2594  C CD  . GLN A 1 370 ? 208.669 231.105 111.805 1.00 40.88  ? 402  GLN B CD  1 
ATOM   2595  O OE1 . GLN A 1 370 ? 208.806 232.269 112.150 1.00 40.88  ? 402  GLN B OE1 1 
ATOM   2596  N NE2 . GLN A 1 370 ? 209.575 230.229 112.164 1.00 40.88  ? 402  GLN B NE2 1 
ATOM   2597  N N   . GLU A 1 371 ? 204.648 228.962 109.408 1.00 22.21  ? 403  GLU B N   1 
ATOM   2598  C CA  . GLU A 1 371 ? 203.874 227.816 109.894 1.00 22.21  ? 403  GLU B CA  1 
ATOM   2599  C C   . GLU A 1 371 ? 204.567 227.083 111.049 1.00 22.21  ? 403  GLU B C   1 
ATOM   2600  O O   . GLU A 1 371 ? 205.625 226.477 110.873 1.00 22.21  ? 403  GLU B O   1 
ATOM   2601  C CB  . GLU A 1 371 ? 203.505 226.864 108.745 1.00 29.27  ? 403  GLU B CB  1 
ATOM   2602  C CG  . GLU A 1 371 ? 202.908 225.522 109.218 1.00 29.27  ? 403  GLU B CG  1 
ATOM   2603  C CD  . GLU A 1 371 ? 201.908 225.668 110.371 1.00 29.27  ? 403  GLU B CD  1 
ATOM   2604  O OE1 . GLU A 1 371 ? 201.077 226.602 110.333 1.00 29.27  ? 403  GLU B OE1 1 
ATOM   2605  O OE2 . GLU A 1 371 ? 202.001 224.887 111.353 1.00 29.27  ? 403  GLU B OE2 1 
ATOM   2606  N N   . GLY A 1 372 ? 203.907 227.057 112.208 1.00 25.64  ? 404  GLY B N   1 
ATOM   2607  C CA  . GLY A 1 372 ? 204.399 226.509 113.474 1.00 25.64  ? 404  GLY B CA  1 
ATOM   2608  C C   . GLY A 1 372 ? 205.097 225.151 113.415 1.00 25.64  ? 404  GLY B C   1 
ATOM   2609  O O   . GLY A 1 372 ? 206.144 225.002 114.045 1.00 25.64  ? 404  GLY B O   1 
ATOM   2610  N N   . LYS A 1 373 ? 204.575 224.179 112.658 1.00 26.56  ? 405  LYS B N   1 
ATOM   2611  C CA  . LYS A 1 373 ? 205.143 222.814 112.575 1.00 26.56  ? 405  LYS B CA  1 
ATOM   2612  C C   . LYS A 1 373 ? 205.887 222.492 111.287 1.00 26.56  ? 405  LYS B C   1 
ATOM   2613  O O   . LYS A 1 373 ? 206.116 221.316 111.021 1.00 26.56  ? 405  LYS B O   1 
ATOM   2614  C CB  . LYS A 1 373 ? 204.052 221.761 112.855 1.00 37.99  ? 405  LYS B CB  1 
ATOM   2615  N N   . VAL A 1 374 ? 206.248 223.468 110.449 1.00 33.15  ? 406  VAL B N   1 
ATOM   2616  C CA  . VAL A 1 374 ? 206.558 223.165 109.076 1.00 33.15  ? 406  VAL B CA  1 
ATOM   2617  C C   . VAL A 1 374 ? 207.835 222.357 109.045 1.00 33.15  ? 406  VAL B C   1 
ATOM   2618  O O   . VAL A 1 374 ? 208.028 221.502 108.186 1.00 33.15  ? 406  VAL B O   1 
ATOM   2619  C CB  . VAL A 1 374 ? 206.717 224.455 108.270 1.00 46.68  ? 406  VAL B CB  1 
ATOM   2620  C CG1 . VAL A 1 374 ? 208.047 225.173 108.538 1.00 46.68  ? 406  VAL B CG1 1 
ATOM   2621  C CG2 . VAL A 1 374 ? 206.570 224.137 106.916 1.00 46.68  ? 406  VAL B CG2 1 
ATOM   2622  N N   . GLN A 1 375 ? 208.682 222.587 110.028 1.00 52.02  ? 407  GLN B N   1 
ATOM   2623  C CA  . GLN A 1 375 ? 209.911 221.883 110.181 1.00 52.02  ? 407  GLN B CA  1 
ATOM   2624  C C   . GLN A 1 375 ? 209.689 220.409 110.274 1.00 52.02  ? 407  GLN B C   1 
ATOM   2625  O O   . GLN A 1 375 ? 210.494 219.646 109.763 1.00 52.02  ? 407  GLN B O   1 
ATOM   2626  C CB  . GLN A 1 375 ? 210.565 222.327 111.467 1.00 70.70  ? 407  GLN B CB  1 
ATOM   2627  C CG  . GLN A 1 375 ? 211.876 221.701 111.767 1.00 70.70  ? 407  GLN B CG  1 
ATOM   2628  C CD  . GLN A 1 375 ? 212.377 222.209 113.018 1.00 70.70  ? 407  GLN B CD  1 
ATOM   2629  O OE1 . GLN A 1 375 ? 211.586 222.658 113.842 1.00 70.70  ? 407  GLN B OE1 1 
ATOM   2630  N NE2 . GLN A 1 375 ? 213.663 222.163 113.221 1.00 70.70  ? 407  GLN B NE2 1 
ATOM   2631  N N   . PHE A 1 376 ? 208.642 219.992 110.981 1.00 34.20  ? 408  PHE B N   1 
ATOM   2632  C CA  . PHE A 1 376 ? 208.366 218.591 111.183 1.00 34.20  ? 408  PHE B CA  1 
ATOM   2633  C C   . PHE A 1 376 ? 207.880 217.938 109.913 1.00 34.20  ? 408  PHE B C   1 
ATOM   2634  O O   . PHE A 1 376 ? 208.326 216.848 109.593 1.00 34.20  ? 408  PHE B O   1 
ATOM   2635  C CB  . PHE A 1 376 ? 207.331 218.413 112.280 1.00 46.25  ? 408  PHE B CB  1 
ATOM   2636  C CG  . PHE A 1 376 ? 207.844 218.801 113.631 1.00 46.25  ? 408  PHE B CG  1 
ATOM   2637  C CD1 . PHE A 1 376 ? 208.973 218.152 114.154 1.00 46.25  ? 408  PHE B CD1 1 
ATOM   2638  C CD2 . PHE A 1 376 ? 207.164 219.762 114.379 1.00 46.25  ? 408  PHE B CD2 1 
ATOM   2639  C CE1 . PHE A 1 376 ? 209.449 218.492 115.422 1.00 46.25  ? 408  PHE B CE1 1 
ATOM   2640  C CE2 . PHE A 1 376 ? 207.641 220.105 115.649 1.00 46.25  ? 408  PHE B CE2 1 
ATOM   2641  C CZ  . PHE A 1 376 ? 208.790 219.484 116.161 1.00 46.25  ? 408  PHE B CZ  1 
ATOM   2642  N N   . VAL A 1 377 ? 206.971 218.571 109.174 1.00 52.02  ? 409  VAL B N   1 
ATOM   2643  C CA  . VAL A 1 377 ? 206.499 217.930 107.950 1.00 52.02  ? 409  VAL B CA  1 
ATOM   2644  C C   . VAL A 1 377 ? 207.613 217.884 106.940 1.00 52.02  ? 409  VAL B C   1 
ATOM   2645  O O   . VAL A 1 377 ? 207.734 216.883 106.249 1.00 52.02  ? 409  VAL B O   1 
ATOM   2646  C CB  . VAL A 1 377 ? 205.236 218.541 107.351 1.00 73.26  ? 409  VAL B CB  1 
ATOM   2647  C CG1 . VAL A 1 377 ? 204.242 218.804 108.476 1.00 73.26  ? 409  VAL B CG1 1 
ATOM   2648  C CG2 . VAL A 1 377 ? 205.460 219.812 106.539 1.00 73.26  ? 409  VAL B CG2 1 
ATOM   2649  N N   . ILE A 1 378 ? 208.453 218.922 106.879 1.00 52.02  ? 410  ILE B N   1 
ATOM   2650  C CA  . ILE A 1 378 ? 209.559 218.884 105.971 1.00 52.02  ? 410  ILE B CA  1 
ATOM   2651  C C   . ILE A 1 378 ? 210.554 217.848 106.411 1.00 52.02  ? 410  ILE B C   1 
ATOM   2652  O O   . ILE A 1 378 ? 211.006 217.031 105.608 1.00 52.02  ? 410  ILE B O   1 
ATOM   2653  C CB  . ILE A 1 378 ? 210.258 220.239 105.845 1.00 73.94  ? 410  ILE B CB  1 
ATOM   2654  C CG1 . ILE A 1 378 ? 209.322 221.244 105.135 1.00 73.94  ? 410  ILE B CG1 1 
ATOM   2655  C CG2 . ILE A 1 378 ? 211.588 220.055 105.131 1.00 73.94  ? 410  ILE B CG2 1 
ATOM   2656  C CD1 . ILE A 1 378 ? 209.802 222.701 105.200 1.00 73.94  ? 410  ILE B CD1 1 
ATOM   2657  N N   . ASP A 1 379 ? 210.891 217.820 107.706 1.00 37.46  ? 411  ASP B N   1 
ATOM   2658  C CA  . ASP A 1 379 ? 211.784 216.843 108.343 1.00 37.46  ? 411  ASP B CA  1 
ATOM   2659  C C   . ASP A 1 379 ? 211.325 215.428 108.024 1.00 37.46  ? 411  ASP B C   1 
ATOM   2660  O O   . ASP A 1 379 ? 212.090 214.642 107.488 1.00 37.46  ? 411  ASP B O   1 
ATOM   2661  C CB  . ASP A 1 379 ? 211.804 217.124 109.859 1.00 47.70  ? 411  ASP B CB  1 
ATOM   2662  C CG  . ASP A 1 379 ? 212.320 216.058 110.828 1.00 47.70  ? 411  ASP B CG  1 
ATOM   2663  O OD1 . ASP A 1 379 ? 212.553 214.904 110.437 1.00 47.70  ? 411  ASP B OD1 1 
ATOM   2664  O OD2 . ASP A 1 379 ? 212.453 216.397 112.025 1.00 47.70  ? 411  ASP B OD2 1 
ATOM   2665  N N   . ALA A 1 380 ? 210.068 215.107 108.305 1.00 37.08  ? 412  ALA B N   1 
ATOM   2666  C CA  . ALA A 1 380 ? 209.559 213.759 108.177 1.00 37.08  ? 412  ALA B CA  1 
ATOM   2667  C C   . ALA A 1 380 ? 209.719 213.238 106.746 1.00 37.08  ? 412  ALA B C   1 
ATOM   2668  O O   . ALA A 1 380 ? 210.190 212.119 106.534 1.00 37.08  ? 412  ALA B O   1 
ATOM   2669  C CB  . ALA A 1 380 ? 208.094 213.765 108.632 1.00 50.09  ? 412  ALA B CB  1 
ATOM   2670  N N   . VAL A 1 381 ? 209.364 214.051 105.750 1.00 52.02  ? 413  VAL B N   1 
ATOM   2671  C CA  . VAL A 1 381 ? 209.497 213.628 104.366 1.00 52.02  ? 413  VAL B CA  1 
ATOM   2672  C C   . VAL A 1 381 ? 210.971 213.470 104.000 1.00 52.02  ? 413  VAL B C   1 
ATOM   2673  O O   . VAL A 1 381 ? 211.330 212.451 103.410 1.00 52.02  ? 413  VAL B O   1 
ATOM   2674  C CB  . VAL A 1 381 ? 208.665 214.509 103.422 1.00 73.26  ? 413  VAL B CB  1 
ATOM   2675  C CG1 . VAL A 1 381 ? 209.211 215.910 103.168 1.00 73.26  ? 413  VAL B CG1 1 
ATOM   2676  C CG2 . VAL A 1 381 ? 208.491 213.820 102.080 1.00 73.26  ? 413  VAL B CG2 1 
ATOM   2677  N N   . TYR A 1 382 ? 211.863 214.364 104.443 1.00 32.60  ? 414  TYR B N   1 
ATOM   2678  C CA  . TYR A 1 382 ? 213.269 214.135 104.213 1.00 32.60  ? 414  TYR B CA  1 
ATOM   2679  C C   . TYR A 1 382 ? 213.729 212.889 104.913 1.00 32.60  ? 414  TYR B C   1 
ATOM   2680  O O   . TYR A 1 382 ? 214.491 212.123 104.340 1.00 32.60  ? 414  TYR B O   1 
ATOM   2681  C CB  . TYR A 1 382 ? 214.133 215.303 104.664 1.00 43.76  ? 414  TYR B CB  1 
ATOM   2682  C CG  . TYR A 1 382 ? 214.371 216.359 103.634 1.00 43.76  ? 414  TYR B CG  1 
ATOM   2683  C CD1 . TYR A 1 382 ? 215.394 216.158 102.729 1.00 43.76  ? 414  TYR B CD1 1 
ATOM   2684  C CD2 . TYR A 1 382 ? 213.641 217.515 103.597 1.00 43.76  ? 414  TYR B CD2 1 
ATOM   2685  C CE1 . TYR A 1 382 ? 215.685 217.113 101.791 1.00 43.76  ? 414  TYR B CE1 1 
ATOM   2686  C CE2 . TYR A 1 382 ? 213.926 218.481 102.654 1.00 43.76  ? 414  TYR B CE2 1 
ATOM   2687  C CZ  . TYR A 1 382 ? 214.954 218.272 101.756 1.00 43.76  ? 414  TYR B CZ  1 
ATOM   2688  O OH  . TYR A 1 382 ? 215.244 219.219 100.839 1.00 43.76  ? 414  TYR B OH  1 
ATOM   2689  N N   . ALA A 1 383 ? 213.308 212.637 106.143 1.00 32.50  ? 415  ALA B N   1 
ATOM   2690  C CA  . ALA A 1 383 ? 213.766 211.492 106.895 1.00 32.50  ? 415  ALA B CA  1 
ATOM   2691  C C   . ALA A 1 383 ? 213.479 210.205 106.131 1.00 32.50  ? 415  ALA B C   1 
ATOM   2692  O O   . ALA A 1 383 ? 214.372 209.382 105.955 1.00 32.50  ? 415  ALA B O   1 
ATOM   2693  C CB  . ALA A 1 383 ? 213.090 211.506 108.266 1.00 43.91  ? 415  ALA B CB  1 
ATOM   2694  N N   . MET A 1 384 ? 212.263 210.060 105.594 1.00 52.02  ? 416  MET B N   1 
ATOM   2695  C CA  . MET A 1 384 ? 211.966 208.912 104.749 1.00 52.02  ? 416  MET B CA  1 
ATOM   2696  C C   . MET A 1 384 ? 212.851 208.925 103.508 1.00 52.02  ? 416  MET B C   1 
ATOM   2697  O O   . MET A 1 384 ? 213.407 207.892 103.159 1.00 52.02  ? 416  MET B O   1 
ATOM   2698  C CB  . MET A 1 384 ? 210.474 208.837 104.400 1.00 72.37  ? 416  MET B CB  1 
ATOM   2699  C CG  . MET A 1 384 ? 210.166 207.501 103.724 1.00 72.37  ? 416  MET B CG  1 
ATOM   2700  S SD  . MET A 1 384 ? 208.419 207.050 103.577 1.00 72.37  ? 416  MET B SD  1 
ATOM   2701  C CE  . MET A 1 384 ? 207.943 206.800 105.296 1.00 72.37  ? 416  MET B CE  1 
ATOM   2702  N N   . GLY A 1 385 ? 213.075 210.082 102.882 1.00 34.69  ? 417  GLY B N   1 
ATOM   2703  C CA  . GLY A 1 385 ? 213.942 210.155 101.718 1.00 34.69  ? 417  GLY B CA  1 
ATOM   2704  C C   . GLY A 1 385 ? 215.349 209.676 102.064 1.00 34.69  ? 417  GLY B C   1 
ATOM   2705  O O   . GLY A 1 385 ? 215.980 208.963 101.278 1.00 34.69  ? 417  GLY B O   1 
ATOM   2706  N N   . HIS A 1 386 ? 215.811 209.999 103.270 1.00 28.20  ? 418  HIS B N   1 
ATOM   2707  C CA  . HIS A 1 386 ? 217.126 209.603 103.718 1.00 28.20  ? 418  HIS B CA  1 
ATOM   2708  C C   . HIS A 1 386 ? 217.142 208.113 103.995 1.00 28.20  ? 418  HIS B C   1 
ATOM   2709  O O   . HIS A 1 386 ? 218.137 207.438 103.710 1.00 28.20  ? 418  HIS B O   1 
ATOM   2710  C CB  . HIS A 1 386 ? 217.553 210.387 104.959 1.00 37.46  ? 418  HIS B CB  1 
ATOM   2711  C CG  . HIS A 1 386 ? 217.888 211.822 104.711 1.00 37.46  ? 418  HIS B CG  1 
ATOM   2712  N ND1 . HIS A 1 386 ? 218.967 212.212 103.951 1.00 37.46  ? 418  HIS B ND1 1 
ATOM   2713  C CD2 . HIS A 1 386 ? 217.314 212.954 105.145 1.00 37.46  ? 418  HIS B CD2 1 
ATOM   2714  C CE1 . HIS A 1 386 ? 219.031 213.528 103.928 1.00 37.46  ? 418  HIS B CE1 1 
ATOM   2715  N NE2 . HIS A 1 386 ? 218.047 214.004 104.651 1.00 37.46  ? 418  HIS B NE2 1 
ATOM   2716  N N   . ALA A 1 387 ? 216.053 207.578 104.541 1.00 34.68  ? 419  ALA B N   1 
ATOM   2717  C CA  . ALA A 1 387 ? 215.978 206.146 104.766 1.00 34.68  ? 419  ALA B CA  1 
ATOM   2718  C C   . ALA A 1 387 ? 215.982 205.391 103.438 1.00 34.68  ? 419  ALA B C   1 
ATOM   2719  O O   . ALA A 1 387 ? 216.619 204.345 103.327 1.00 34.68  ? 419  ALA B O   1 
ATOM   2720  C CB  . ALA A 1 387 ? 214.747 205.804 105.564 1.00 46.85  ? 419  ALA B CB  1 
ATOM   2721  N N   . LEU A 1 388 ? 215.306 205.942 102.426 1.00 52.02  ? 420  LEU B N   1 
ATOM   2722  C CA  . LEU A 1 388 ? 215.240 205.351 101.098 1.00 52.02  ? 420  LEU B CA  1 
ATOM   2723  C C   . LEU A 1 388 ? 216.609 205.406 100.453 1.00 52.02  ? 420  LEU B C   1 
ATOM   2724  O O   . LEU A 1 388 ? 217.024 204.482 99.758  1.00 52.02  ? 420  LEU B O   1 
ATOM   2725  C CB  . LEU A 1 388 ? 214.203 206.104 100.262 1.00 73.94  ? 420  LEU B CB  1 
ATOM   2726  C CG  . LEU A 1 388 ? 212.742 205.928 100.658 1.00 73.94  ? 420  LEU B CG  1 
ATOM   2727  C CD1 . LEU A 1 388 ? 211.880 206.977 99.919  1.00 73.94  ? 420  LEU B CD1 1 
ATOM   2728  C CD2 . LEU A 1 388 ? 212.287 204.552 100.294 1.00 73.94  ? 420  LEU B CD2 1 
ATOM   2729  N N   . HIS A 1 389 ? 217.326 206.480 100.706 1.00 52.02  ? 421  HIS B N   1 
ATOM   2730  C CA  . HIS A 1 389 ? 218.671 206.665 100.220 1.00 52.02  ? 421  HIS B CA  1 
ATOM   2731  C C   . HIS A 1 389 ? 219.571 205.602 100.853 1.00 52.02  ? 421  HIS B C   1 
ATOM   2732  O O   . HIS A 1 389 ? 220.376 204.957 100.165 1.00 52.02  ? 421  HIS B O   1 
ATOM   2733  C CB  . HIS A 1 389 ? 219.087 208.089 100.552 1.00 69.09  ? 421  HIS B CB  1 
ATOM   2734  C CG  . HIS A 1 389 ? 220.392 208.528 100.106 1.00 69.09  ? 421  HIS B CG  1 
ATOM   2735  N ND1 . HIS A 1 389 ? 220.702 208.760 98.784  1.00 69.09  ? 421  HIS B ND1 1 
ATOM   2736  C CD2 . HIS A 1 389 ? 221.490 208.838 100.813 1.00 69.09  ? 421  HIS B CD2 1 
ATOM   2737  C CE1 . HIS A 1 389 ? 221.963 209.168 98.709  1.00 69.09  ? 421  HIS B CE1 1 
ATOM   2738  N NE2 . HIS A 1 389 ? 222.452 209.227 99.925  1.00 69.09  ? 421  HIS B NE2 1 
ATOM   2739  N N   . ALA A 1 390 ? 219.441 205.415 102.176 1.00 35.46  ? 422  ALA B N   1 
ATOM   2740  C CA  . ALA A 1 390 ? 220.216 204.409 102.882 1.00 35.46  ? 422  ALA B CA  1 
ATOM   2741  C C   . ALA A 1 390 ? 219.904 203.021 102.346 1.00 35.46  ? 422  ALA B C   1 
ATOM   2742  O O   . ALA A 1 390 ? 220.803 202.196 102.197 1.00 35.46  ? 422  ALA B O   1 
ATOM   2743  C CB  . ALA A 1 390 ? 219.939 204.495 104.357 1.00 47.90  ? 422  ALA B CB  1 
ATOM   2744  N N   . MET A 1 391 ? 218.638 202.775 102.013 1.00 36.90  ? 423  MET B N   1 
ATOM   2745  C CA  . MET A 1 391 ? 218.234 201.532 101.387 1.00 36.90  ? 423  MET B CA  1 
ATOM   2746  C C   . MET A 1 391 ? 218.893 201.329 100.048 1.00 36.90  ? 423  MET B C   1 
ATOM   2747  O O   . MET A 1 391 ? 219.475 200.277 99.770  1.00 36.90  ? 423  MET B O   1 
ATOM   2748  C CB  . MET A 1 391 ? 216.759 201.537 101.148 1.00 51.34  ? 423  MET B CB  1 
ATOM   2749  C CG  . MET A 1 391 ? 215.938 201.303 102.262 1.00 51.34  ? 423  MET B CG  1 
ATOM   2750  S SD  . MET A 1 391 ? 215.969 199.604 102.726 1.00 51.34  ? 423  MET B SD  1 
ATOM   2751  C CE  . MET A 1 391 ? 215.170 198.744 101.403 1.00 51.34  ? 423  MET B CE  1 
ATOM   2752  N N   . HIS A 1 392 ? 218.928 202.360 99.228  1.00 36.02  ? 424  HIS B N   1 
ATOM   2753  C CA  . HIS A 1 392 ? 219.548 202.145 97.944  1.00 36.02  ? 424  HIS B CA  1 
ATOM   2754  C C   . HIS A 1 392 ? 221.004 201.796 98.132  1.00 36.02  ? 424  HIS B C   1 
ATOM   2755  O O   . HIS A 1 392 ? 221.472 200.810 97.597  1.00 36.02  ? 424  HIS B O   1 
ATOM   2756  C CB  . HIS A 1 392 ? 219.402 203.362 97.040  1.00 47.84  ? 424  HIS B CB  1 
ATOM   2757  C CG  . HIS A 1 392 ? 218.036 203.504 96.524  1.00 47.84  ? 424  HIS B CG  1 
ATOM   2758  N ND1 . HIS A 1 392 ? 217.468 202.574 95.679  1.00 47.84  ? 424  HIS B ND1 1 
ATOM   2759  C CD2 . HIS A 1 392 ? 217.104 204.454 96.720  1.00 47.84  ? 424  HIS B CD2 1 
ATOM   2760  C CE1 . HIS A 1 392 ? 216.248 202.948 95.381  1.00 47.84  ? 424  HIS B CE1 1 
ATOM   2761  N NE2 . HIS A 1 392 ? 215.998 204.085 96.002  1.00 47.84  ? 424  HIS B NE2 1 
ATOM   2762  N N   . ARG A 1 393 ? 221.668 202.415 99.083  1.00 33.73  ? 425  ARG B N   1 
ATOM   2763  C CA  . ARG A 1 393 ? 223.075 202.128 99.315  1.00 33.73  ? 425  ARG B CA  1 
ATOM   2764  C C   . ARG A 1 393 ? 223.340 200.733 99.937  1.00 33.73  ? 425  ARG B C   1 
ATOM   2765  O O   . ARG A 1 393 ? 224.497 200.336 100.097 1.00 33.73  ? 425  ARG B O   1 
ATOM   2766  C CB  . ARG A 1 393 ? 223.672 203.209 100.191 1.00 47.37  ? 425  ARG B CB  1 
ATOM   2767  C CG  . ARG A 1 393 ? 223.750 204.578 99.514  1.00 47.37  ? 425  ARG B CG  1 
ATOM   2768  C CD  . ARG A 1 393 ? 224.253 205.624 100.422 1.00 47.37  ? 425  ARG B CD  1 
ATOM   2769  N NE  . ARG A 1 393 ? 223.320 205.930 101.496 1.00 47.37  ? 425  ARG B NE  1 
ATOM   2770  C CZ  . ARG A 1 393 ? 223.642 206.609 102.627 1.00 47.37  ? 425  ARG B CZ  1 
ATOM   2771  N NH1 . ARG A 1 393 ? 222.725 206.859 103.547 1.00 47.37  ? 425  ARG B NH1 1 
ATOM   2772  N NH2 . ARG A 1 393 ? 224.874 207.028 102.820 1.00 47.37  ? 425  ARG B NH2 1 
ATOM   2773  N N   . ASP A 1 394 ? 222.277 200.037 100.341 1.00 35.25  ? 426  ASP B N   1 
ATOM   2774  C CA  . ASP A 1 394 ? 222.267 198.721 100.973 1.00 35.25  ? 426  ASP B CA  1 
ATOM   2775  C C   . ASP A 1 394 ? 221.704 197.685 100.001 1.00 35.25  ? 426  ASP B C   1 
ATOM   2776  O O   . ASP A 1 394 ? 222.405 196.778 99.545  1.00 35.25  ? 426  ASP B O   1 
ATOM   2777  C CB  . ASP A 1 394 ? 221.408 198.751 102.247 1.00 44.89  ? 426  ASP B CB  1 
ATOM   2778  C CG  . ASP A 1 394 ? 221.352 197.419 103.009 1.00 44.89  ? 426  ASP B CG  1 
ATOM   2779  O OD1 . ASP A 1 394 ? 222.087 196.540 102.688 1.00 44.89  ? 426  ASP B OD1 1 
ATOM   2780  O OD2 . ASP A 1 394 ? 220.516 197.289 103.901 1.00 44.89  ? 426  ASP B OD2 1 
ATOM   2781  N N   . LEU A 1 395 ? 220.410 197.828 99.710  1.00 34.18  ? 427  LEU B N   1 
ATOM   2782  C CA  . LEU A 1 395 ? 219.650 196.974 98.807  1.00 34.18  ? 427  LEU B CA  1 
ATOM   2783  C C   . LEU A 1 395 ? 220.160 197.030 97.358  1.00 34.18  ? 427  LEU B C   1 
ATOM   2784  O O   . LEU A 1 395 ? 220.187 195.983 96.695  1.00 34.18  ? 427  LEU B O   1 
ATOM   2785  C CB  . LEU A 1 395 ? 218.157 197.415 98.802  1.00 48.58  ? 427  LEU B CB  1 
ATOM   2786  C CG  . LEU A 1 395 ? 217.157 196.609 97.894  1.00 48.58  ? 427  LEU B CG  1 
ATOM   2787  C CD1 . LEU A 1 395 ? 217.080 195.161 98.338  1.00 48.58  ? 427  LEU B CD1 1 
ATOM   2788  C CD2 . LEU A 1 395 ? 215.786 197.278 97.935  1.00 48.58  ? 427  LEU B CD2 1 
ATOM   2789  N N   . CYS A 1 396 ? 220.536 198.248 96.866  1.00 43.82  ? 428  CYS B N   1 
ATOM   2790  C CA  . CYS A 1 396 ? 220.963 198.512 95.490  1.00 43.82  ? 428  CYS B CA  1 
ATOM   2791  C C   . CYS A 1 396 ? 222.271 199.325 95.485  1.00 43.82  ? 428  CYS B C   1 
ATOM   2792  O O   . CYS A 1 396 ? 222.355 200.385 94.849  1.00 43.82  ? 428  CYS B O   1 
ATOM   2793  C CB  . CYS A 1 396 ? 219.843 199.275 94.747  1.00 56.78  ? 428  CYS B CB  1 
ATOM   2794  S SG  . CYS A 1 396 ? 218.256 198.410 94.703  1.00 56.78  ? 428  CYS B SG  1 
ATOM   2795  N N   . PRO A 1 397 ? 223.355 198.806 96.086  1.00 38.61  ? 429  PRO B N   1 
ATOM   2796  C CA  . PRO A 1 397 ? 224.583 199.522 96.389  1.00 38.61  ? 429  PRO B CA  1 
ATOM   2797  C C   . PRO A 1 397 ? 225.348 199.973 95.160  1.00 38.61  ? 429  PRO B C   1 
ATOM   2798  O O   . PRO A 1 397 ? 226.220 200.837 95.239  1.00 38.61  ? 429  PRO B O   1 
ATOM   2799  C CB  . PRO A 1 397 ? 225.388 198.476 97.163  1.00 65.98  ? 429  PRO B CB  1 
ATOM   2800  C CG  . PRO A 1 397 ? 224.866 197.145 96.676  1.00 65.98  ? 429  PRO B CG  1 
ATOM   2801  C CD  . PRO A 1 397 ? 223.410 197.370 96.405  1.00 65.98  ? 429  PRO B CD  1 
ATOM   2802  N N   . GLY A 1 398 ? 225.056 199.347 94.026  1.00 32.04  ? 430  GLY B N   1 
ATOM   2803  C CA  . GLY A 1 398 ? 225.723 199.653 92.777  1.00 32.04  ? 430  GLY B CA  1 
ATOM   2804  C C   . GLY A 1 398 ? 224.882 200.513 91.836  1.00 32.04  ? 430  GLY B C   1 
ATOM   2805  O O   . GLY A 1 398 ? 225.238 200.663 90.665  1.00 32.04  ? 430  GLY B O   1 
ATOM   2806  N N   . ARG A 1 399 ? 223.752 201.053 92.308  1.00 32.79  ? 431  ARG B N   1 
ATOM   2807  C CA  . ARG A 1 399 ? 222.885 201.790 91.393  1.00 32.79  ? 431  ARG B CA  1 
ATOM   2808  C C   . ARG A 1 399 ? 222.450 203.178 91.827  1.00 32.79  ? 431  ARG B C   1 
ATOM   2809  O O   . ARG A 1 399 ? 222.385 203.515 93.010  1.00 32.79  ? 431  ARG B O   1 
ATOM   2810  C CB  . ARG A 1 399 ? 221.619 200.992 91.119  1.00 47.94  ? 431  ARG B CB  1 
ATOM   2811  C CG  . ARG A 1 399 ? 221.844 199.651 90.437  1.00 47.94  ? 431  ARG B CG  1 
ATOM   2812  C CD  . ARG A 1 399 ? 220.577 198.927 90.209  1.00 47.94  ? 431  ARG B CD  1 
ATOM   2813  N NE  . ARG A 1 399 ? 219.735 199.534 89.153  1.00 47.94  ? 431  ARG B NE  1 
ATOM   2814  C CZ  . ARG A 1 399 ? 219.831 199.282 87.840  1.00 47.94  ? 431  ARG B CZ  1 
ATOM   2815  N NH1 . ARG A 1 399 ? 219.000 199.910 87.044  1.00 47.94  ? 431  ARG B NH1 1 
ATOM   2816  N NH2 . ARG A 1 399 ? 220.723 198.435 87.358  1.00 47.94  ? 431  ARG B NH2 1 
ATOM   2817  N N   . VAL A 1 400 ? 222.133 203.970 90.815  1.00 30.48  ? 432  VAL B N   1 
ATOM   2818  C CA  . VAL A 1 400 ? 221.530 205.282 90.944  1.00 30.48  ? 432  VAL B CA  1 
ATOM   2819  C C   . VAL A 1 400 ? 220.329 205.206 90.038  1.00 30.48  ? 432  VAL B C   1 
ATOM   2820  O O   . VAL A 1 400 ? 220.318 204.378 89.122  1.00 30.48  ? 432  VAL B O   1 
ATOM   2821  C CB  . VAL A 1 400 ? 222.491 206.408 90.528  1.00 42.92  ? 432  VAL B CB  1 
ATOM   2822  C CG1 . VAL A 1 400 ? 223.712 206.395 91.423  1.00 42.92  ? 432  VAL B CG1 1 
ATOM   2823  C CG2 . VAL A 1 400 ? 222.903 206.226 89.072  1.00 42.92  ? 432  VAL B CG2 1 
ATOM   2824  N N   . GLY A 1 401 ? 219.356 206.065 90.233  1.00 29.97  ? 433  GLY B N   1 
ATOM   2825  C CA  . GLY A 1 401 ? 218.179 205.971 89.410  1.00 29.97  ? 433  GLY B CA  1 
ATOM   2826  C C   . GLY A 1 401 ? 217.445 204.746 89.909  1.00 29.97  ? 433  GLY B C   1 
ATOM   2827  O O   . GLY A 1 401 ? 217.714 204.271 91.015  1.00 29.97  ? 433  GLY B O   1 
ATOM   2828  N N   . LEU A 1 402 ? 216.554 204.201 89.104  1.00 44.69  ? 434  LEU B N   1 
ATOM   2829  C CA  . LEU A 1 402 ? 215.780 203.058 89.553  1.00 44.69  ? 434  LEU B CA  1 
ATOM   2830  C C   . LEU A 1 402 ? 216.544 201.739 89.657  1.00 44.69  ? 434  LEU B C   1 
ATOM   2831  O O   . LEU A 1 402 ? 217.420 201.437 88.835  1.00 44.69  ? 434  LEU B O   1 
ATOM   2832  C CB  . LEU A 1 402 ? 214.573 202.846 88.635  1.00 63.52  ? 434  LEU B CB  1 
ATOM   2833  C CG  . LEU A 1 402 ? 213.485 203.883 88.713  1.00 63.52  ? 434  LEU B CG  1 
ATOM   2834  C CD1 . LEU A 1 402 ? 212.501 203.670 87.596  1.00 63.52  ? 434  LEU B CD1 1 
ATOM   2835  C CD2 . LEU A 1 402 ? 212.740 203.705 90.062  1.00 63.52  ? 434  LEU B CD2 1 
ATOM   2836  N N   . CYS A 1 403 ? 216.135 200.941 90.664  1.00 51.75  ? 435  CYS B N   1 
ATOM   2837  C CA  . CYS A 1 403 ? 216.563 199.604 90.986  1.00 51.75  ? 435  CYS B CA  1 
ATOM   2838  C C   . CYS A 1 403 ? 215.283 198.785 91.233  1.00 51.75  ? 435  CYS B C   1 
ATOM   2839  O O   . CYS A 1 403 ? 214.565 199.049 92.210  1.00 51.75  ? 435  CYS B O   1 
ATOM   2840  C CB  . CYS A 1 403 ? 217.446 199.608 92.234  1.00 67.06  ? 435  CYS B CB  1 
ATOM   2841  S SG  . CYS A 1 403 ? 218.032 198.003 92.740  1.00 67.06  ? 435  CYS B SG  1 
ATOM   2842  N N   . PRO A 1 404 ? 214.976 197.777 90.396  1.00 47.32  ? 436  PRO B N   1 
ATOM   2843  C CA  . PRO A 1 404 ? 213.786 196.939 90.453  1.00 47.32  ? 436  PRO B CA  1 
ATOM   2844  C C   . PRO A 1 404 ? 213.568 196.271 91.799  1.00 47.32  ? 436  PRO B C   1 
ATOM   2845  O O   . PRO A 1 404 ? 212.435 195.964 92.157  1.00 47.32  ? 436  PRO B O   1 
ATOM   2846  C CB  . PRO A 1 404 ? 214.078 195.880 89.386  1.00 80.86  ? 436  PRO B CB  1 
ATOM   2847  C CG  . PRO A 1 404 ? 215.000 196.557 88.412  1.00 80.86  ? 436  PRO B CG  1 
ATOM   2848  C CD  . PRO A 1 404 ? 215.860 197.470 89.243  1.00 80.86  ? 436  PRO B CD  1 
ATOM   2849  N N   . ARG A 1 405 ? 214.640 196.097 92.568  1.00 41.41  ? 437  ARG B N   1 
ATOM   2850  C CA  . ARG A 1 405 ? 214.591 195.441 93.864  1.00 41.41  ? 437  ARG B CA  1 
ATOM   2851  C C   . ARG A 1 405 ? 213.741 196.220 94.848  1.00 41.41  ? 437  ARG B C   1 
ATOM   2852  O O   . ARG A 1 405 ? 213.219 195.654 95.809  1.00 41.41  ? 437  ARG B O   1 
ATOM   2853  C CB  . ARG A 1 405 ? 215.975 195.348 94.459  1.00 58.16  ? 437  ARG B CB  1 
ATOM   2854  C CG  . ARG A 1 405 ? 216.943 194.454 93.745  1.00 58.16  ? 437  ARG B CG  1 
ATOM   2855  C CD  . ARG A 1 405 ? 218.309 194.510 94.360  1.00 58.16  ? 437  ARG B CD  1 
ATOM   2856  N NE  . ARG A 1 405 ? 219.251 193.710 93.601  1.00 58.16  ? 437  ARG B NE  1 
ATOM   2857  C CZ  . ARG A 1 405 ? 220.594 193.677 93.774  1.00 58.16  ? 437  ARG B CZ  1 
ATOM   2858  N NH1 . ARG A 1 405 ? 221.320 192.897 92.986  1.00 58.16  ? 437  ARG B NH1 1 
ATOM   2859  N NH2 . ARG A 1 405 ? 221.196 194.396 94.703  1.00 58.16  ? 437  ARG B NH2 1 
ATOM   2860  N N   . MET A 1 406 ? 213.623 197.533 94.647  1.00 46.83  ? 438  MET B N   1 
ATOM   2861  C CA  . MET A 1 406 ? 212.844 198.315 95.575  1.00 46.83  ? 438  MET B CA  1 
ATOM   2862  C C   . MET A 1 406 ? 211.387 198.385 95.164  1.00 46.83  ? 438  MET B C   1 
ATOM   2863  O O   . MET A 1 406 ? 210.587 198.980 95.872  1.00 46.83  ? 438  MET B O   1 
ATOM   2864  C CB  . MET A 1 406 ? 213.422 199.728 95.797  1.00 65.15  ? 438  MET B CB  1 
ATOM   2865  C CG  . MET A 1 406 ? 212.658 200.576 96.923  1.00 65.15  ? 438  MET B CG  1 
ATOM   2866  S SD  . MET A 1 406 ? 213.389 202.138 97.359  1.00 65.15  ? 438  MET B SD  1 
ATOM   2867  C CE  . MET A 1 406 ? 214.707 201.639 98.440  1.00 65.15  ? 438  MET B CE  1 
ATOM   2868  N N   . ASP A 1 407 ? 210.999 197.871 94.001  1.00 45.95  ? 439  ASP B N   1 
ATOM   2869  C CA  . ASP A 1 407 ? 209.590 198.027 93.707  1.00 45.95  ? 439  ASP B CA  1 
ATOM   2870  C C   . ASP A 1 407 ? 208.814 197.183 94.751  1.00 45.95  ? 439  ASP B C   1 
ATOM   2871  O O   . ASP A 1 407 ? 208.199 197.760 95.656  1.00 45.95  ? 439  ASP B O   1 
ATOM   2872  C CB  . ASP A 1 407 ? 209.287 197.791 92.205  1.00 58.51  ? 439  ASP B CB  1 
ATOM   2873  C CG  . ASP A 1 407 ? 207.838 198.085 91.803  1.00 58.51  ? 439  ASP B CG  1 
ATOM   2874  O OD1 . ASP A 1 407 ? 207.486 199.235 91.808  1.00 58.51  ? 439  ASP B OD1 1 
ATOM   2875  O OD2 . ASP A 1 407 ? 207.080 197.183 91.525  1.00 58.51  ? 439  ASP B OD2 1 
ATOM   2876  N N   . PRO A 1 408 ? 208.912 195.836 94.782  1.00 39.49  ? 440  PRO B N   1 
ATOM   2877  C CA  . PRO A 1 408 ? 208.347 194.999 95.816  1.00 39.49  ? 440  PRO B CA  1 
ATOM   2878  C C   . PRO A 1 408 ? 209.302 195.003 96.999  1.00 39.49  ? 440  PRO B C   1 
ATOM   2879  O O   . PRO A 1 408 ? 209.884 193.968 97.325  1.00 39.49  ? 440  PRO B O   1 
ATOM   2880  C CB  . PRO A 1 408 ? 208.298 193.628 95.152  1.00 67.48  ? 440  PRO B CB  1 
ATOM   2881  C CG  . PRO A 1 408 ? 209.506 193.638 94.252  1.00 67.48  ? 440  PRO B CG  1 
ATOM   2882  C CD  . PRO A 1 408 ? 209.585 195.056 93.732  1.00 67.48  ? 440  PRO B CD  1 
ATOM   2883  N N   . VAL A 1 409 ? 209.520 196.161 97.585  1.00 30.16  ? 441  VAL B N   1 
ATOM   2884  C CA  . VAL A 1 409 ? 210.486 196.265 98.661  1.00 30.16  ? 441  VAL B CA  1 
ATOM   2885  C C   . VAL A 1 409 ? 209.894 195.747 99.941  1.00 30.16  ? 441  VAL B C   1 
ATOM   2886  O O   . VAL A 1 409 ? 208.736 196.018 100.256 1.00 30.16  ? 441  VAL B O   1 
ATOM   2887  C CB  . VAL A 1 409 ? 210.958 197.719 98.850  1.00 42.47  ? 441  VAL B CB  1 
ATOM   2888  C CG1 . VAL A 1 409 ? 209.852 198.605 99.310  1.00 42.47  ? 441  VAL B CG1 1 
ATOM   2889  C CG2 . VAL A 1 409 ? 212.130 197.785 99.811  1.00 42.47  ? 441  VAL B CG2 1 
ATOM   2890  N N   . ASP A 1 410 ? 210.670 194.989 100.692 1.00 34.20  ? 442  ASP B N   1 
ATOM   2891  C CA  . ASP A 1 410 ? 210.162 194.525 101.961 1.00 34.20  ? 442  ASP B CA  1 
ATOM   2892  C C   . ASP A 1 410 ? 210.314 195.666 102.928 1.00 34.20  ? 442  ASP B C   1 
ATOM   2893  O O   . ASP A 1 410 ? 211.439 196.077 103.259 1.00 34.20  ? 442  ASP B O   1 
ATOM   2894  C CB  . ASP A 1 410 ? 210.855 193.260 102.469 1.00 43.55  ? 442  ASP B CB  1 
ATOM   2895  C CG  . ASP A 1 410 ? 210.188 192.704 103.789 1.00 43.55  ? 442  ASP B CG  1 
ATOM   2896  O OD1 . ASP A 1 410 ? 209.796 193.496 104.646 1.00 43.55  ? 442  ASP B OD1 1 
ATOM   2897  O OD2 . ASP A 1 410 ? 210.018 191.498 103.895 1.00 43.55  ? 442  ASP B OD2 1 
ATOM   2898  N N   . GLY A 1 411 ? 209.190 196.173 103.391 1.00 25.07  ? 443  GLY B N   1 
ATOM   2899  C CA  . GLY A 1 411 ? 209.173 197.338 104.231 1.00 25.07  ? 443  GLY B CA  1 
ATOM   2900  C C   . GLY A 1 411 ? 209.916 197.152 105.528 1.00 25.07  ? 443  GLY B C   1 
ATOM   2901  O O   . GLY A 1 411 ? 210.192 198.128 106.213 1.00 25.07  ? 443  GLY B O   1 
ATOM   2902  N N   . THR A 1 412 ? 210.226 195.924 105.884 1.00 27.05  ? 444  THR B N   1 
ATOM   2903  C CA  . THR A 1 412 ? 210.956 195.643 107.088 1.00 27.05  ? 444  THR B CA  1 
ATOM   2904  C C   . THR A 1 412 ? 212.331 196.265 106.959 1.00 27.05  ? 444  THR B C   1 
ATOM   2905  O O   . THR A 1 412 ? 212.887 196.787 107.928 1.00 27.05  ? 444  THR B O   1 
ATOM   2906  C CB  . THR A 1 412 ? 211.129 194.133 107.313 1.00 37.03  ? 444  THR B CB  1 
ATOM   2907  O OG1 . THR A 1 412 ? 209.847 193.509 107.370 1.00 37.03  ? 444  THR B OG1 1 
ATOM   2908  C CG2 . THR A 1 412 ? 211.842 193.902 108.627 1.00 37.03  ? 444  THR B CG2 1 
ATOM   2909  N N   . GLN A 1 413 ? 212.920 196.173 105.765 1.00 26.64  ? 445  GLN B N   1 
ATOM   2910  C CA  . GLN A 1 413 ? 214.253 196.695 105.581 1.00 26.64  ? 445  GLN B CA  1 
ATOM   2911  C C   . GLN A 1 413 ? 214.114 198.203 105.524 1.00 26.64  ? 445  GLN B C   1 
ATOM   2912  O O   . GLN A 1 413 ? 215.003 198.940 105.967 1.00 26.64  ? 445  GLN B O   1 
ATOM   2913  C CB  . GLN A 1 413 ? 214.904 196.133 104.327 1.00 36.21  ? 445  GLN B CB  1 
ATOM   2914  C CG  . GLN A 1 413 ? 216.417 196.411 104.219 1.00 36.21  ? 445  GLN B CG  1 
ATOM   2915  C CD  . GLN A 1 413 ? 217.009 195.851 102.929 1.00 36.21  ? 445  GLN B CD  1 
ATOM   2916  O OE1 . GLN A 1 413 ? 216.253 195.355 102.084 1.00 36.21  ? 445  GLN B OE1 1 
ATOM   2917  N NE2 . GLN A 1 413 ? 218.328 195.913 102.767 1.00 36.21  ? 445  GLN B NE2 1 
ATOM   2918  N N   . LEU A 1 414 ? 212.978 198.670 104.986 1.00 24.52  ? 446  LEU B N   1 
ATOM   2919  C CA  . LEU A 1 414 ? 212.775 200.111 104.944 1.00 24.52  ? 446  LEU B CA  1 
ATOM   2920  C C   . LEU A 1 414 ? 212.707 200.619 106.388 1.00 24.52  ? 446  LEU B C   1 
ATOM   2921  O O   . LEU A 1 414 ? 213.296 201.655 106.703 1.00 24.52  ? 446  LEU B O   1 
ATOM   2922  C CB  . LEU A 1 414 ? 211.444 200.532 104.276 1.00 34.85  ? 446  LEU B CB  1 
ATOM   2923  C CG  . LEU A 1 414 ? 211.196 200.304 102.748 1.00 34.85  ? 446  LEU B CG  1 
ATOM   2924  C CD1 . LEU A 1 414 ? 209.749 200.694 102.419 1.00 34.85  ? 446  LEU B CD1 1 
ATOM   2925  C CD2 . LEU A 1 414 ? 212.103 201.120 101.957 1.00 34.85  ? 446  LEU B CD2 1 
ATOM   2926  N N   . LEU A 1 415 ? 212.008 199.890 107.282 1.00 23.53  ? 447  LEU B N   1 
ATOM   2927  C CA  . LEU A 1 415 ? 211.870 200.195 108.711 1.00 23.53  ? 447  LEU B CA  1 
ATOM   2928  C C   . LEU A 1 415 ? 213.213 200.230 109.409 1.00 23.53  ? 447  LEU B C   1 
ATOM   2929  O O   . LEU A 1 415 ? 213.415 201.070 110.290 1.00 23.53  ? 447  LEU B O   1 
ATOM   2930  C CB  . LEU A 1 415 ? 211.049 199.139 109.471 1.00 33.44  ? 447  LEU B CB  1 
ATOM   2931  C CG  . LEU A 1 415 ? 209.542 199.071 109.246 1.00 33.44  ? 447  LEU B CG  1 
ATOM   2932  C CD1 . LEU A 1 415 ? 209.022 197.889 110.057 1.00 33.44  ? 447  LEU B CD1 1 
ATOM   2933  C CD2 . LEU A 1 415 ? 208.839 200.346 109.682 1.00 33.44  ? 447  LEU B CD2 1 
ATOM   2934  N N   . LYS A 1 416 ? 214.132 199.338 109.020 1.00 28.23  ? 448  LYS B N   1 
ATOM   2935  C CA  . LYS A 1 416 ? 215.430 199.323 109.647 1.00 28.23  ? 448  LYS B CA  1 
ATOM   2936  C C   . LYS A 1 416 ? 216.110 200.637 109.384 1.00 28.23  ? 448  LYS B C   1 
ATOM   2937  O O   . LYS A 1 416 ? 216.606 201.252 110.322 1.00 28.23  ? 448  LYS B O   1 
ATOM   2938  C CB  . LYS A 1 416 ? 216.297 198.185 109.119 1.00 40.38  ? 448  LYS B CB  1 
ATOM   2939  C CG  . LYS A 1 416 ? 215.865 196.814 109.568 1.00 40.38  ? 448  LYS B CG  1 
ATOM   2940  C CD  . LYS A 1 416 ? 216.737 195.738 108.964 1.00 40.38  ? 448  LYS B CD  1 
ATOM   2941  C CE  . LYS A 1 416 ? 216.249 194.355 109.357 1.00 40.38  ? 448  LYS B CE  1 
ATOM   2942  N NZ  . LYS A 1 416 ? 217.068 193.273 108.736 1.00 40.38  ? 448  LYS B NZ  1 
ATOM   2943  N N   . TYR A 1 417 ? 216.021 201.142 108.157 1.00 31.31  ? 449  TYR B N   1 
ATOM   2944  C CA  . TYR A 1 417 ? 216.647 202.420 107.877 1.00 31.31  ? 449  TYR B CA  1 
ATOM   2945  C C   . TYR A 1 417 ? 215.896 203.597 108.428 1.00 31.31  ? 449  TYR B C   1 
ATOM   2946  O O   . TYR A 1 417 ? 216.506 204.572 108.855 1.00 31.31  ? 449  TYR B O   1 
ATOM   2947  C CB  . TYR A 1 417 ? 216.938 202.563 106.415 1.00 42.03  ? 449  TYR B CB  1 
ATOM   2948  C CG  . TYR A 1 417 ? 218.058 201.718 106.133 1.00 42.03  ? 449  TYR B CG  1 
ATOM   2949  C CD1 . TYR A 1 417 ? 219.301 202.073 106.598 1.00 42.03  ? 449  TYR B CD1 1 
ATOM   2950  C CD2 . TYR A 1 417 ? 217.874 200.568 105.480 1.00 42.03  ? 449  TYR B CD2 1 
ATOM   2951  C CE1 . TYR A 1 417 ? 220.353 201.265 106.389 1.00 42.03  ? 449  TYR B CE1 1 
ATOM   2952  C CE2 . TYR A 1 417 ? 218.920 199.744 105.254 1.00 42.03  ? 449  TYR B CE2 1 
ATOM   2953  C CZ  . TYR A 1 417 ? 220.173 200.102 105.722 1.00 42.03  ? 449  TYR B CZ  1 
ATOM   2954  O OH  . TYR A 1 417 ? 221.231 199.276 105.532 1.00 42.03  ? 449  TYR B OH  1 
ATOM   2955  N N   . ILE A 1 418 ? 214.577 203.502 108.566 1.00 52.02  ? 450  ILE B N   1 
ATOM   2956  C CA  . ILE A 1 418 ? 213.782 204.510 109.280 1.00 52.02  ? 450  ILE B CA  1 
ATOM   2957  C C   . ILE A 1 418 ? 214.297 204.704 110.710 1.00 52.02  ? 450  ILE B C   1 
ATOM   2958  O O   . ILE A 1 418 ? 214.489 205.834 111.152 1.00 52.02  ? 450  ILE B O   1 
ATOM   2959  C CB  . ILE A 1 418 ? 212.296 204.113 109.213 1.00 73.94  ? 450  ILE B CB  1 
ATOM   2960  C CG1 . ILE A 1 418 ? 211.813 204.403 107.780 1.00 73.94  ? 450  ILE B CG1 1 
ATOM   2961  C CG2 . ILE A 1 418 ? 211.420 204.816 110.257 1.00 73.94  ? 450  ILE B CG2 1 
ATOM   2962  C CD1 . ILE A 1 418 ? 210.453 203.790 107.444 1.00 73.94  ? 450  ILE B CD1 1 
ATOM   2963  N N   . ARG A 1 419 ? 214.587 203.610 111.420 1.00 32.92  ? 451  ARG B N   1 
ATOM   2964  C CA  . ARG A 1 419 ? 215.184 203.671 112.758 1.00 32.92  ? 451  ARG B CA  1 
ATOM   2965  C C   . ARG A 1 419 ? 216.694 203.914 112.739 1.00 32.92  ? 451  ARG B C   1 
ATOM   2966  O O   . ARG A 1 419 ? 217.196 204.569 113.648 1.00 32.92  ? 451  ARG B O   1 
ATOM   2967  C CB  . ARG A 1 419 ? 214.825 202.386 113.511 1.00 46.23  ? 451  ARG B CB  1 
ATOM   2968  C CG  . ARG A 1 419 ? 213.351 202.407 113.941 1.00 46.23  ? 451  ARG B CG  1 
ATOM   2969  C CD  . ARG A 1 419 ? 212.865 200.998 114.295 1.00 46.23  ? 451  ARG B CD  1 
ATOM   2970  N NE  . ARG A 1 419 ? 211.558 201.023 114.971 1.00 46.23  ? 451  ARG B NE  1 
ATOM   2971  C CZ  . ARG A 1 419 ? 210.380 201.350 114.481 1.00 46.23  ? 451  ARG B CZ  1 
ATOM   2972  N NH1 . ARG A 1 419 ? 209.363 201.391 115.281 1.00 46.23  ? 451  ARG B NH1 1 
ATOM   2973  N NH2 . ARG A 1 419 ? 210.186 201.655 113.232 1.00 46.23  ? 451  ARG B NH2 1 
ATOM   2974  N N   . ASN A 1 420 ? 217.433 203.418 111.741 1.00 24.91  ? 452  ASN B N   1 
ATOM   2975  C CA  . ASN A 1 420 ? 218.896 203.506 111.744 1.00 24.91  ? 452  ASN B CA  1 
ATOM   2976  C C   . ASN A 1 420 ? 219.449 204.844 111.266 1.00 24.91  ? 452  ASN B C   1 
ATOM   2977  O O   . ASN A 1 420 ? 220.541 205.256 111.683 1.00 24.91  ? 452  ASN B O   1 
ATOM   2978  C CB  . ASN A 1 420 ? 219.512 202.418 110.886 1.00 33.13  ? 452  ASN B CB  1 
ATOM   2979  C CG  . ASN A 1 420 ? 219.382 201.049 111.461 1.00 33.13  ? 452  ASN B CG  1 
ATOM   2980  O OD1 . ASN A 1 420 ? 219.207 200.862 112.670 1.00 33.13  ? 452  ASN B OD1 1 
ATOM   2981  N ND2 . ASN A 1 420 ? 219.466 200.064 110.609 1.00 33.13  ? 452  ASN B ND2 1 
ATOM   2982  N N   . VAL A 1 421 ? 218.729 205.523 110.386 1.00 25.27  ? 453  VAL B N   1 
ATOM   2983  C CA  . VAL A 1 421 ? 219.221 206.766 109.844 1.00 25.27  ? 453  VAL B CA  1 
ATOM   2984  C C   . VAL A 1 421 ? 219.058 207.912 110.833 1.00 25.27  ? 453  VAL B C   1 
ATOM   2985  O O   . VAL A 1 421 ? 217.968 208.236 111.298 1.00 25.27  ? 453  VAL B O   1 
ATOM   2986  C CB  . VAL A 1 421 ? 218.535 207.023 108.485 1.00 35.59  ? 453  VAL B CB  1 
ATOM   2987  C CG1 . VAL A 1 421 ? 218.894 208.343 107.906 1.00 35.59  ? 453  VAL B CG1 1 
ATOM   2988  C CG2 . VAL A 1 421 ? 218.992 205.940 107.521 1.00 35.59  ? 453  VAL B CG2 1 
ATOM   2989  N N   . ASN A 1 422 ? 220.196 208.540 111.089 1.00 21.06  ? 454  ASN B N   1 
ATOM   2990  C CA  . ASN A 1 422 ? 220.409 209.630 112.023 1.00 21.06  ? 454  ASN B CA  1 
ATOM   2991  C C   . ASN A 1 422 ? 221.153 210.735 111.310 1.00 21.06  ? 454  ASN B C   1 
ATOM   2992  O O   . ASN A 1 422 ? 222.201 210.501 110.705 1.00 21.06  ? 454  ASN B O   1 
ATOM   2993  C CB  . ASN A 1 422 ? 221.162 209.124 113.231 1.00 28.01  ? 454  ASN B CB  1 
ATOM   2994  C CG  . ASN A 1 422 ? 220.299 208.295 114.152 1.00 28.01  ? 454  ASN B CG  1 
ATOM   2995  O OD1 . ASN A 1 422 ? 219.731 208.887 115.077 1.00 28.01  ? 454  ASN B OD1 1 
ATOM   2996  N ND2 . ASN A 1 422 ? 220.177 207.004 113.947 1.00 28.01  ? 454  ASN B ND2 1 
ATOM   2997  N N   . PHE A 1 423 ? 220.563 211.914 111.294 1.00 18.57  ? 455  PHE B N   1 
ATOM   2998  C CA  . PHE A 1 423 ? 221.130 213.020 110.526 1.00 18.57  ? 455  PHE B CA  1 
ATOM   2999  C C   . PHE A 1 423 ? 220.747 214.374 111.082 1.00 18.57  ? 455  PHE B C   1 
ATOM   3000  O O   . PHE A 1 423 ? 219.873 214.465 111.932 1.00 18.57  ? 455  PHE B O   1 
ATOM   3001  C CB  . PHE A 1 423 ? 220.674 212.880 109.069 1.00 25.11  ? 455  PHE B CB  1 
ATOM   3002  C CG  . PHE A 1 423 ? 219.173 212.975 108.878 1.00 25.11  ? 455  PHE B CG  1 
ATOM   3003  C CD1 . PHE A 1 423 ? 218.365 211.895 109.130 1.00 25.11  ? 455  PHE B CD1 1 
ATOM   3004  C CD2 . PHE A 1 423 ? 218.581 214.144 108.478 1.00 25.11  ? 455  PHE B CD2 1 
ATOM   3005  C CE1 . PHE A 1 423 ? 217.019 211.972 108.975 1.00 25.11  ? 455  PHE B CE1 1 
ATOM   3006  C CE2 . PHE A 1 423 ? 217.230 214.234 108.325 1.00 25.11  ? 455  PHE B CE2 1 
ATOM   3007  C CZ  . PHE A 1 423 ? 216.452 213.159 108.570 1.00 25.11  ? 455  PHE B CZ  1 
ATOM   3008  N N   . SER A 1 424 ? 221.422 215.437 110.660 1.00 21.54  ? 456  SER B N   1 
ATOM   3009  C CA  . SER A 1 424 ? 220.972 216.761 111.078 1.00 21.54  ? 456  SER B CA  1 
ATOM   3010  C C   . SER A 1 424 ? 219.808 217.101 110.182 1.00 21.54  ? 456  SER B C   1 
ATOM   3011  O O   . SER A 1 424 ? 219.939 217.035 108.959 1.00 21.54  ? 456  SER B O   1 
ATOM   3012  C CB  . SER A 1 424 ? 222.066 217.794 110.935 1.00 28.69  ? 456  SER B CB  1 
ATOM   3013  O OG  . SER A 1 424 ? 223.138 217.517 111.793 1.00 28.69  ? 456  SER B OG  1 
ATOM   3014  N N   . GLY A 1 425 ? 218.678 217.471 110.755 1.00 24.34  ? 457  GLY B N   1 
ATOM   3015  C CA  . GLY A 1 425 ? 217.505 217.724 109.963 1.00 24.34  ? 457  GLY B CA  1 
ATOM   3016  C C   . GLY A 1 425 ? 217.408 219.140 109.517 1.00 24.34  ? 457  GLY B C   1 
ATOM   3017  O O   . GLY A 1 425 ? 218.365 219.926 109.607 1.00 24.34  ? 457  GLY B O   1 
ATOM   3018  N N   . ILE A 1 426 ? 216.237 219.482 109.031 1.00 31.33  ? 458  ILE B N   1 
ATOM   3019  C CA  . ILE A 1 426 ? 216.093 220.819 108.523 1.00 31.33  ? 458  ILE B CA  1 
ATOM   3020  C C   . ILE A 1 426 ? 216.165 221.787 109.690 1.00 31.33  ? 458  ILE B C   1 
ATOM   3021  O O   . ILE A 1 426 ? 215.787 221.466 110.825 1.00 31.33  ? 458  ILE B O   1 
ATOM   3022  C CB  . ILE A 1 426 ? 214.852 221.016 107.641 1.00 44.53  ? 458  ILE B CB  1 
ATOM   3023  C CG1 . ILE A 1 426 ? 215.059 222.334 106.851 1.00 44.53  ? 458  ILE B CG1 1 
ATOM   3024  C CG2 . ILE A 1 426 ? 213.566 221.066 108.476 1.00 44.53  ? 458  ILE B CG2 1 
ATOM   3025  C CD1 . ILE A 1 426 ? 214.167 222.516 105.721 1.00 44.53  ? 458  ILE B CD1 1 
ATOM   3026  N N   . ALA A 1 427 ? 216.800 222.922 109.423 1.00 30.14  ? 459  ALA B N   1 
ATOM   3027  C CA  . ALA A 1 427 ? 217.050 223.998 110.369 1.00 30.14  ? 459  ALA B CA  1 
ATOM   3028  C C   . ALA A 1 427 ? 218.091 223.566 111.401 1.00 30.14  ? 459  ALA B C   1 
ATOM   3029  O O   . ALA A 1 427 ? 218.375 224.298 112.344 1.00 30.14  ? 459  ALA B O   1 
ATOM   3030  C CB  . ALA A 1 427 ? 215.753 224.445 111.057 1.00 40.72  ? 459  ALA B CB  1 
ATOM   3031  N N   . GLY A 1 428 ? 218.735 222.419 111.172 1.00 29.16  ? 460  GLY B N   1 
ATOM   3032  C CA  . GLY A 1 428 ? 219.807 221.937 112.019 1.00 29.16  ? 460  GLY B CA  1 
ATOM   3033  C C   . GLY A 1 428 ? 219.345 221.120 113.211 1.00 29.16  ? 460  GLY B C   1 
ATOM   3034  O O   . GLY A 1 428 ? 220.147 220.826 114.093 1.00 29.16  ? 460  GLY B O   1 
ATOM   3035  N N   . ASN A 1 429 ? 218.068 220.758 113.262 1.00 32.73  ? 461  ASN B N   1 
ATOM   3036  C CA  . ASN A 1 429 ? 217.538 219.985 114.379 1.00 32.73  ? 461  ASN B CA  1 
ATOM   3037  C C   . ASN A 1 429 ? 217.891 218.502 114.197 1.00 32.73  ? 461  ASN B C   1 
ATOM   3038  O O   . ASN A 1 429 ? 217.399 217.903 113.251 1.00 32.73  ? 461  ASN B O   1 
ATOM   3039  C CB  . ASN A 1 429 ? 216.036 220.146 114.440 1.00 43.54  ? 461  ASN B CB  1 
ATOM   3040  C CG  . ASN A 1 429 ? 215.400 219.553 115.650 1.00 43.54  ? 461  ASN B CG  1 
ATOM   3041  O OD1 . ASN A 1 429 ? 216.050 218.885 116.453 1.00 43.54  ? 461  ASN B OD1 1 
ATOM   3042  N ND2 . ASN A 1 429 ? 214.121 219.794 115.814 1.00 43.54  ? 461  ASN B ND2 1 
ATOM   3043  N N   . PRO A 1 430 ? 218.720 217.859 115.038 1.00 26.05  ? 462  PRO B N   1 
ATOM   3044  C CA  . PRO A 1 430 ? 219.114 216.471 114.874 1.00 26.05  ? 462  PRO B CA  1 
ATOM   3045  C C   . PRO A 1 430 ? 217.893 215.582 114.782 1.00 26.05  ? 462  PRO B C   1 
ATOM   3046  O O   . PRO A 1 430 ? 216.963 215.710 115.577 1.00 26.05  ? 462  PRO B O   1 
ATOM   3047  C CB  . PRO A 1 430 ? 219.887 216.187 116.165 1.00 44.51  ? 462  PRO B CB  1 
ATOM   3048  C CG  . PRO A 1 430 ? 220.424 217.531 116.575 1.00 44.51  ? 462  PRO B CG  1 
ATOM   3049  C CD  . PRO A 1 430 ? 219.321 218.513 116.211 1.00 44.51  ? 462  PRO B CD  1 
ATOM   3050  N N   . VAL A 1 431 ? 217.869 214.715 113.778 1.00 20.73  ? 463  VAL B N   1 
ATOM   3051  C CA  . VAL A 1 431 ? 216.830 213.719 113.565 1.00 20.73  ? 463  VAL B CA  1 
ATOM   3052  C C   . VAL A 1 431 ? 217.314 212.411 114.136 1.00 20.73  ? 463  VAL B C   1 
ATOM   3053  O O   . VAL A 1 431 ? 218.206 211.754 113.602 1.00 20.73  ? 463  VAL B O   1 
ATOM   3054  C CB  . VAL A 1 431 ? 216.461 213.560 112.089 1.00 29.19  ? 463  VAL B CB  1 
ATOM   3055  C CG1 . VAL A 1 431 ? 215.426 212.443 111.917 1.00 29.19  ? 463  VAL B CG1 1 
ATOM   3056  C CG2 . VAL A 1 431 ? 215.863 214.877 111.603 1.00 29.19  ? 463  VAL B CG2 1 
ATOM   3057  N N   . THR A 1 432 ? 216.687 212.047 115.239 1.00 22.10  ? 464  THR B N   1 
ATOM   3058  C CA  . THR A 1 432 ? 216.809 210.745 115.868 1.00 22.10  ? 464  THR B CA  1 
ATOM   3059  C C   . THR A 1 432 ? 215.488 210.415 116.548 1.00 22.10  ? 464  THR B C   1 
ATOM   3060  O O   . THR A 1 432 ? 214.823 211.293 117.101 1.00 22.10  ? 464  THR B O   1 
ATOM   3061  C CB  . THR A 1 432 ? 217.987 210.736 116.847 1.00 30.25  ? 464  THR B CB  1 
ATOM   3062  O OG1 . THR A 1 432 ? 218.242 209.416 117.239 1.00 30.25  ? 464  THR B OG1 1 
ATOM   3063  C CG2 . THR A 1 432 ? 217.778 211.553 118.117 1.00 30.25  ? 464  THR B CG2 1 
ATOM   3064  N N   . PHE A 1 433 ? 215.108 209.148 116.544 1.00 26.96  ? 465  PHE B N   1 
ATOM   3065  C CA  . PHE A 1 433 ? 214.065 208.629 117.414 1.00 26.96  ? 465  PHE B CA  1 
ATOM   3066  C C   . PHE A 1 433 ? 214.370 207.177 117.753 1.00 26.96  ? 465  PHE B C   1 
ATOM   3067  O O   . PHE A 1 433 ? 215.044 206.470 117.002 1.00 26.96  ? 465  PHE B O   1 
ATOM   3068  C CB  . PHE A 1 433 ? 212.672 208.819 116.802 1.00 36.46  ? 465  PHE B CB  1 
ATOM   3069  C CG  . PHE A 1 433 ? 212.565 208.489 115.339 1.00 36.46  ? 465  PHE B CG  1 
ATOM   3070  C CD1 . PHE A 1 433 ? 212.581 207.154 114.914 1.00 36.46  ? 465  PHE B CD1 1 
ATOM   3071  C CD2 . PHE A 1 433 ? 212.452 209.530 114.406 1.00 36.46  ? 465  PHE B CD2 1 
ATOM   3072  C CE1 . PHE A 1 433 ? 212.482 206.860 113.548 1.00 36.46  ? 465  PHE B CE1 1 
ATOM   3073  C CE2 . PHE A 1 433 ? 212.351 209.236 113.042 1.00 36.46  ? 465  PHE B CE2 1 
ATOM   3074  C CZ  . PHE A 1 433 ? 212.364 207.900 112.615 1.00 36.46  ? 465  PHE B CZ  1 
ATOM   3075  N N   . ASN A 1 434 ? 213.901 206.745 118.917 1.00 29.25  ? 466  ASN B N   1 
ATOM   3076  C CA  . ASN A 1 434 ? 214.169 205.407 119.402 1.00 29.25  ? 466  ASN B CA  1 
ATOM   3077  C C   . ASN A 1 434 ? 213.368 204.350 118.623 1.00 29.25  ? 466  ASN B C   1 
ATOM   3078  O O   . ASN A 1 434 ? 212.683 204.611 117.635 1.00 29.25  ? 466  ASN B O   1 
ATOM   3079  C CB  . ASN A 1 434 ? 213.956 205.377 120.928 1.00 38.91  ? 466  ASN B CB  1 
ATOM   3080  C CG  . ASN A 1 434 ? 214.468 204.130 121.625 1.00 38.91  ? 466  ASN B CG  1 
ATOM   3081  O OD1 . ASN A 1 434 ? 215.435 203.497 121.227 1.00 38.91  ? 466  ASN B OD1 1 
ATOM   3082  N ND2 . ASN A 1 434 ? 213.862 203.768 122.726 1.00 38.91  ? 466  ASN B ND2 1 
ATOM   3083  N N   . GLU A 1 435 ? 213.436 203.124 119.097 1.00 32.14  ? 467  GLU B N   1 
ATOM   3084  C CA  . GLU A 1 435 ? 212.919 201.964 118.396 1.00 32.14  ? 467  GLU B CA  1 
ATOM   3085  C C   . GLU A 1 435 ? 211.410 201.849 118.506 1.00 32.14  ? 467  GLU B C   1 
ATOM   3086  O O   . GLU A 1 435 ? 210.774 201.165 117.704 1.00 32.14  ? 467  GLU B O   1 
ATOM   3087  C CB  . GLU A 1 435 ? 213.590 200.694 118.922 1.00 42.36  ? 467  GLU B CB  1 
ATOM   3088  C CG  . GLU A 1 435 ? 213.261 200.326 120.379 1.00 42.36  ? 467  GLU B CG  1 
ATOM   3089  C CD  . GLU A 1 435 ? 214.119 201.032 121.393 1.00 42.36  ? 467  GLU B CD  1 
ATOM   3090  O OE1 . GLU A 1 435 ? 214.729 202.025 121.048 1.00 42.36  ? 467  GLU B OE1 1 
ATOM   3091  O OE2 . GLU A 1 435 ? 214.164 200.590 122.511 1.00 42.36  ? 467  GLU B OE2 1 
ATOM   3092  N N   . ASN A 1 436 ? 210.812 202.521 119.486 1.00 30.60  ? 468  ASN B N   1 
ATOM   3093  C CA  . ASN A 1 436 ? 209.374 202.719 119.586 1.00 30.60  ? 468  ASN B CA  1 
ATOM   3094  C C   . ASN A 1 436 ? 208.953 203.975 118.822 1.00 30.60  ? 468  ASN B C   1 
ATOM   3095  O O   . ASN A 1 436 ? 207.793 204.374 118.897 1.00 30.60  ? 468  ASN B O   1 
ATOM   3096  C CB  . ASN A 1 436 ? 208.946 202.806 121.063 1.00 40.70  ? 468  ASN B CB  1 
ATOM   3097  C CG  . ASN A 1 436 ? 209.175 201.532 121.847 1.00 40.70  ? 468  ASN B CG  1 
ATOM   3098  O OD1 . ASN A 1 436 ? 209.795 200.587 121.397 1.00 40.70  ? 468  ASN B OD1 1 
ATOM   3099  N ND2 . ASN A 1 436 ? 208.670 201.458 123.050 1.00 40.70  ? 468  ASN B ND2 1 
ATOM   3100  N N   . GLY A 1 437 ? 209.877 204.633 118.121 1.00 28.26  ? 469  GLY B N   1 
ATOM   3101  C CA  . GLY A 1 437 ? 209.593 205.792 117.295 1.00 28.26  ? 469  GLY B CA  1 
ATOM   3102  C C   . GLY A 1 437 ? 209.253 207.056 118.071 1.00 28.26  ? 469  GLY B C   1 
ATOM   3103  O O   . GLY A 1 437 ? 208.450 207.833 117.574 1.00 28.26  ? 469  GLY B O   1 
ATOM   3104  N N   . ASP A 1 438 ? 209.821 207.271 119.259 1.00 33.71  ? 470  ASP B N   1 
ATOM   3105  C CA  . ASP A 1 438 ? 209.755 208.567 119.952 1.00 33.71  ? 470  ASP B CA  1 
ATOM   3106  C C   . ASP A 1 438 ? 211.029 209.369 119.690 1.00 33.71  ? 470  ASP B C   1 
ATOM   3107  O O   . ASP A 1 438 ? 212.137 208.889 119.938 1.00 33.71  ? 470  ASP B O   1 
ATOM   3108  C CB  . ASP A 1 438 ? 209.587 208.389 121.481 1.00 42.93  ? 470  ASP B CB  1 
ATOM   3109  C CG  . ASP A 1 438 ? 208.203 207.874 121.885 1.00 42.93  ? 470  ASP B CG  1 
ATOM   3110  O OD1 . ASP A 1 438 ? 207.286 207.924 121.038 1.00 42.93  ? 470  ASP B OD1 1 
ATOM   3111  O OD2 . ASP A 1 438 ? 208.022 207.393 123.024 1.00 42.93  ? 470  ASP B OD2 1 
ATOM   3112  N N   . ALA A 1 439 ? 210.891 210.611 119.237 1.00 37.58  ? 471  ALA B N   1 
ATOM   3113  C CA  . ALA A 1 439 ? 212.019 211.525 119.324 1.00 37.58  ? 471  ALA B CA  1 
ATOM   3114  C C   . ALA A 1 439 ? 212.293 211.838 120.809 1.00 37.58  ? 471  ALA B C   1 
ATOM   3115  O O   . ALA A 1 439 ? 211.350 211.888 121.600 1.00 37.58  ? 471  ALA B O   1 
ATOM   3116  C CB  . ALA A 1 439 ? 211.750 212.760 118.475 1.00 50.77  ? 471  ALA B CB  1 
ATOM   3117  N N   . PRO A 1 440 ? 213.552 212.016 121.226 1.00 40.40  ? 472  PRO B N   1 
ATOM   3118  C CA  . PRO A 1 440 ? 213.921 211.994 122.640 1.00 40.40  ? 472  PRO B CA  1 
ATOM   3119  C C   . PRO A 1 440 ? 213.575 213.289 123.394 1.00 40.40  ? 472  PRO B C   1 
ATOM   3120  O O   . PRO A 1 440 ? 214.437 214.134 123.636 1.00 40.40  ? 472  PRO B O   1 
ATOM   3121  C CB  . PRO A 1 440 ? 215.416 211.666 122.637 1.00 69.03  ? 472  PRO B CB  1 
ATOM   3122  C CG  . PRO A 1 440 ? 215.903 212.279 121.331 1.00 69.03  ? 472  PRO B CG  1 
ATOM   3123  C CD  . PRO A 1 440 ? 214.737 212.008 120.387 1.00 69.03  ? 472  PRO B CD  1 
ATOM   3124  N N   . GLY A 1 441 ? 212.308 213.426 123.793 1.00 36.64  ? 473  GLY B N   1 
ATOM   3125  C CA  . GLY A 1 441 ? 211.764 214.316 124.844 1.00 36.64  ? 473  GLY B CA  1 
ATOM   3126  C C   . GLY A 1 441 ? 211.770 215.834 124.604 1.00 36.64  ? 473  GLY B C   1 
ATOM   3127  O O   . GLY A 1 441 ? 210.858 216.544 125.019 1.00 36.64  ? 473  GLY B O   1 
ATOM   3128  N N   . ARG A 1 442 ? 212.796 216.334 123.936 1.00 33.22  ? 474  ARG B N   1 
ATOM   3129  C CA  . ARG A 1 442 ? 213.219 217.733 123.854 1.00 33.22  ? 474  ARG B CA  1 
ATOM   3130  C C   . ARG A 1 442 ? 212.151 218.683 123.303 1.00 33.22  ? 474  ARG B C   1 
ATOM   3131  O O   . ARG A 1 442 ? 211.773 218.615 122.135 1.00 33.22  ? 474  ARG B O   1 
ATOM   3132  C CB  . ARG A 1 442 ? 214.498 217.673 123.009 1.00 46.65  ? 474  ARG B CB  1 
ATOM   3133  C CG  . ARG A 1 442 ? 215.161 219.013 122.681 1.00 46.65  ? 474  ARG B CG  1 
ATOM   3134  C CD  . ARG A 1 442 ? 216.555 218.764 122.081 1.00 46.65  ? 474  ARG B CD  1 
ATOM   3135  N NE  . ARG A 1 442 ? 216.512 217.845 120.923 1.00 46.65  ? 474  ARG B NE  1 
ATOM   3136  C CZ  . ARG A 1 442 ? 216.371 218.151 119.648 1.00 46.65  ? 474  ARG B CZ  1 
ATOM   3137  N NH1 . ARG A 1 442 ? 216.243 217.221 118.752 1.00 46.65  ? 474  ARG B NH1 1 
ATOM   3138  N NH2 . ARG A 1 442 ? 216.359 219.375 119.213 1.00 46.65  ? 474  ARG B NH2 1 
ATOM   3139  N N   . TYR A 1 443 ? 211.692 219.614 124.132 1.00 22.27  ? 475  TYR B N   1 
ATOM   3140  C CA  . TYR A 1 443 ? 210.686 220.599 123.734 1.00 22.27  ? 475  TYR B CA  1 
ATOM   3141  C C   . TYR A 1 443 ? 210.780 221.925 124.520 1.00 22.27  ? 475  TYR B C   1 
ATOM   3142  O O   . TYR A 1 443 ? 211.411 221.988 125.576 1.00 22.27  ? 475  TYR B O   1 
ATOM   3143  C CB  . TYR A 1 443 ? 209.310 219.946 123.791 1.00 29.89  ? 475  TYR B CB  1 
ATOM   3144  C CG  . TYR A 1 443 ? 208.983 219.538 125.171 1.00 29.89  ? 475  TYR B CG  1 
ATOM   3145  C CD1 . TYR A 1 443 ? 209.541 218.367 125.683 1.00 29.89  ? 475  TYR B CD1 1 
ATOM   3146  C CD2 . TYR A 1 443 ? 208.342 220.465 125.998 1.00 29.89  ? 475  TYR B CD2 1 
ATOM   3147  C CE1 . TYR A 1 443 ? 209.446 218.130 127.058 1.00 29.89  ? 475  TYR B CE1 1 
ATOM   3148  C CE2 . TYR A 1 443 ? 208.312 220.266 127.372 1.00 29.89  ? 475  TYR B CE2 1 
ATOM   3149  C CZ  . TYR A 1 443 ? 208.837 219.087 127.901 1.00 29.89  ? 475  TYR B CZ  1 
ATOM   3150  O OH  . TYR A 1 443 ? 208.784 218.920 129.242 1.00 29.89  ? 475  TYR B OH  1 
ATOM   3151  N N   . ASP A 1 444 ? 210.167 222.996 124.000 1.00 22.30  ? 476  ASP B N   1 
ATOM   3152  C CA  . ASP A 1 444 ? 210.282 224.341 124.580 1.00 22.30  ? 476  ASP B CA  1 
ATOM   3153  C C   . ASP A 1 444 ? 208.991 224.820 125.272 1.00 22.30  ? 476  ASP B C   1 
ATOM   3154  O O   . ASP A 1 444 ? 207.871 224.535 124.828 1.00 22.30  ? 476  ASP B O   1 
ATOM   3155  C CB  . ASP A 1 444 ? 210.718 225.359 123.531 1.00 28.40  ? 476  ASP B CB  1 
ATOM   3156  C CG  . ASP A 1 444 ? 212.209 225.271 123.140 1.00 28.40  ? 476  ASP B CG  1 
ATOM   3157  O OD1 . ASP A 1 444 ? 213.012 224.873 123.948 1.00 28.40  ? 476  ASP B OD1 1 
ATOM   3158  O OD2 . ASP A 1 444 ? 212.542 225.609 122.023 1.00 28.40  ? 476  ASP B OD2 1 
ATOM   3159  N N   . ILE A 1 445 ? 209.160 225.581 126.350 1.00 19.53  ? 477  ILE B N   1 
ATOM   3160  C CA  . ILE A 1 445 ? 208.066 226.131 127.148 1.00 19.53  ? 477  ILE B CA  1 
ATOM   3161  C C   . ILE A 1 445 ? 207.822 227.601 126.835 1.00 19.53  ? 477  ILE B C   1 
ATOM   3162  O O   . ILE A 1 445 ? 208.724 228.428 127.017 1.00 19.53  ? 477  ILE B O   1 
ATOM   3163  C CB  . ILE A 1 445 ? 208.373 226.022 128.663 1.00 27.76  ? 477  ILE B CB  1 
ATOM   3164  C CG1 . ILE A 1 445 ? 208.500 224.618 129.129 1.00 27.76  ? 477  ILE B CG1 1 
ATOM   3165  C CG2 . ILE A 1 445 ? 207.256 226.622 129.429 1.00 27.76  ? 477  ILE B CG2 1 
ATOM   3166  C CD1 . ILE A 1 445 ? 209.827 223.961 128.941 1.00 27.76  ? 477  ILE B CD1 1 
ATOM   3167  N N   . TYR A 1 446 ? 206.581 227.958 126.501 1.00 19.07  ? 478  TYR B N   1 
ATOM   3168  C CA  . TYR A 1 446 ? 206.198 229.294 126.051 1.00 19.07  ? 478  TYR B CA  1 
ATOM   3169  C C   . TYR A 1 446 ? 205.248 229.987 127.037 1.00 19.07  ? 478  TYR B C   1 
ATOM   3170  O O   . TYR A 1 446 ? 204.451 229.346 127.702 1.00 19.07  ? 478  TYR B O   1 
ATOM   3171  C CB  . TYR A 1 446 ? 205.512 229.229 124.671 1.00 25.60  ? 478  TYR B CB  1 
ATOM   3172  C CG  . TYR A 1 446 ? 206.324 228.689 123.506 1.00 25.60  ? 478  TYR B CG  1 
ATOM   3173  C CD1 . TYR A 1 446 ? 206.819 227.371 123.512 1.00 25.60  ? 478  TYR B CD1 1 
ATOM   3174  C CD2 . TYR A 1 446 ? 206.553 229.504 122.385 1.00 25.60  ? 478  TYR B CD2 1 
ATOM   3175  C CE1 . TYR A 1 446 ? 207.606 226.898 122.452 1.00 25.60  ? 478  TYR B CE1 1 
ATOM   3176  C CE2 . TYR A 1 446 ? 207.319 229.027 121.306 1.00 25.60  ? 478  TYR B CE2 1 
ATOM   3177  C CZ  . TYR A 1 446 ? 207.869 227.730 121.350 1.00 25.60  ? 478  TYR B CZ  1 
ATOM   3178  O OH  . TYR A 1 446 ? 208.637 227.283 120.326 1.00 25.60  ? 478  TYR B OH  1 
ATOM   3179  N N   . GLN A 1 447 ? 205.254 231.305 127.082 1.00 21.54  ? 479  GLN B N   1 
ATOM   3180  C CA  . GLN A 1 447 ? 204.326 232.149 127.837 1.00 21.54  ? 479  GLN B CA  1 
ATOM   3181  C C   . GLN A 1 447 ? 203.518 233.066 126.963 1.00 21.54  ? 479  GLN B C   1 
ATOM   3182  O O   . GLN A 1 447 ? 204.073 233.801 126.156 1.00 21.54  ? 479  GLN B O   1 
ATOM   3183  C CB  . GLN A 1 447 ? 205.041 233.116 128.764 1.00 29.28  ? 479  GLN B CB  1 
ATOM   3184  C CG  . GLN A 1 447 ? 204.117 233.900 129.622 1.00 29.28  ? 479  GLN B CG  1 
ATOM   3185  C CD  . GLN A 1 447 ? 204.849 234.632 130.663 1.00 29.28  ? 479  GLN B CD  1 
ATOM   3186  O OE1 . GLN A 1 447 ? 205.857 235.297 130.378 1.00 29.28  ? 479  GLN B OE1 1 
ATOM   3187  N NE2 . GLN A 1 447 ? 204.369 234.506 131.898 1.00 29.28  ? 479  GLN B NE2 1 
ATOM   3188  N N   . TYR A 1 448 ? 202.190 233.120 127.110 1.00 19.38  ? 480  TYR B N   1 
ATOM   3189  C CA  . TYR A 1 448 ? 201.399 234.092 126.343 1.00 19.38  ? 480  TYR B CA  1 
ATOM   3190  C C   . TYR A 1 448 ? 201.375 235.472 126.986 1.00 19.38  ? 480  TYR B C   1 
ATOM   3191  O O   . TYR A 1 448 ? 200.698 235.726 127.974 1.00 19.38  ? 480  TYR B O   1 
ATOM   3192  C CB  . TYR A 1 448 ? 199.991 233.621 126.031 1.00 26.01  ? 480  TYR B CB  1 
ATOM   3193  C CG  . TYR A 1 448 ? 199.351 234.497 124.974 1.00 26.01  ? 480  TYR B CG  1 
ATOM   3194  C CD1 . TYR A 1 448 ? 199.998 234.722 123.742 1.00 26.01  ? 480  TYR B CD1 1 
ATOM   3195  C CD2 . TYR A 1 448 ? 198.114 235.102 125.230 1.00 26.01  ? 480  TYR B CD2 1 
ATOM   3196  C CE1 . TYR A 1 448 ? 199.401 235.524 122.761 1.00 26.01  ? 480  TYR B CE1 1 
ATOM   3197  C CE2 . TYR A 1 448 ? 197.509 235.904 124.248 1.00 26.01  ? 480  TYR B CE2 1 
ATOM   3198  C CZ  . TYR A 1 448 ? 198.152 236.112 123.011 1.00 26.01  ? 480  TYR B CZ  1 
ATOM   3199  O OH  . TYR A 1 448 ? 197.562 236.867 122.052 1.00 26.01  ? 480  TYR B OH  1 
ATOM   3200  N N   . GLN A 1 449 ? 202.140 236.374 126.407 1.00 19.22  ? 481  GLN B N   1 
ATOM   3201  C CA  . GLN A 1 449 ? 202.393 237.724 126.874 1.00 19.22  ? 481  GLN B CA  1 
ATOM   3202  C C   . GLN A 1 449 ? 201.475 238.775 126.277 1.00 19.22  ? 481  GLN B C   1 
ATOM   3203  O O   . GLN A 1 449 ? 201.369 238.905 125.056 1.00 19.22  ? 481  GLN B O   1 
ATOM   3204  C CB  . GLN A 1 449 ? 203.844 238.093 126.561 1.00 26.12  ? 481  GLN B CB  1 
ATOM   3205  C CG  . GLN A 1 449 ? 204.264 239.499 126.966 1.00 26.12  ? 481  GLN B CG  1 
ATOM   3206  C CD  . GLN A 1 449 ? 204.343 239.671 128.466 1.00 26.12  ? 481  GLN B CD  1 
ATOM   3207  O OE1 . GLN A 1 449 ? 205.067 238.926 129.131 1.00 26.12  ? 481  GLN B OE1 1 
ATOM   3208  N NE2 . GLN A 1 449 ? 203.612 240.643 129.017 1.00 26.12  ? 481  GLN B NE2 1 
ATOM   3209  N N   . LEU A 1 450 ? 200.837 239.563 127.135 1.00 21.95  ? 482  LEU B N   1 
ATOM   3210  C CA  . LEU A 1 450 ? 199.964 240.632 126.658 1.00 21.95  ? 482  LEU B CA  1 
ATOM   3211  C C   . LEU A 1 450 ? 200.640 242.010 126.723 1.00 21.95  ? 482  LEU B C   1 
ATOM   3212  O O   . LEU A 1 450 ? 201.553 242.223 127.535 1.00 21.95  ? 482  LEU B O   1 
ATOM   3213  C CB  . LEU A 1 450 ? 198.671 240.650 127.474 1.00 31.20  ? 482  LEU B CB  1 
ATOM   3214  C CG  . LEU A 1 450 ? 197.887 239.350 127.490 1.00 31.20  ? 482  LEU B CG  1 
ATOM   3215  C CD1 . LEU A 1 450 ? 196.673 239.523 128.329 1.00 31.20  ? 482  LEU B CD1 1 
ATOM   3216  C CD2 . LEU A 1 450 ? 197.513 238.951 126.118 1.00 31.20  ? 482  LEU B CD2 1 
ATOM   3217  N N   . ARG A 1 451 ? 200.161 242.957 125.870 1.00 19.80  ? 483  ARG B N   1 
ATOM   3218  C CA  . ARG A 1 451 ? 200.602 244.348 125.773 1.00 19.80  ? 483  ARG B CA  1 
ATOM   3219  C C   . ARG A 1 451 ? 199.626 245.067 124.838 1.00 19.80  ? 483  ARG B C   1 
ATOM   3220  O O   . ARG A 1 451 ? 198.696 244.453 124.301 1.00 19.80  ? 483  ARG B O   1 
ATOM   3221  C CB  . ARG A 1 451 ? 202.062 244.461 125.230 1.00 28.95  ? 483  ARG B CB  1 
ATOM   3222  C CG  . ARG A 1 451 ? 202.702 245.932 125.159 1.00 28.95  ? 483  ARG B CG  1 
ATOM   3223  C CD  . ARG A 1 451 ? 204.181 245.929 124.706 1.00 28.95  ? 483  ARG B CD  1 
ATOM   3224  N NE  . ARG A 1 451 ? 204.756 247.320 124.623 1.00 28.95  ? 483  ARG B NE  1 
ATOM   3225  C CZ  . ARG A 1 451 ? 206.033 247.692 124.202 1.00 28.95  ? 483  ARG B CZ  1 
ATOM   3226  N NH1 . ARG A 1 451 ? 206.366 248.963 124.193 1.00 28.95  ? 483  ARG B NH1 1 
ATOM   3227  N NH2 . ARG A 1 451 ? 206.938 246.818 123.805 1.00 28.95  ? 483  ARG B NH2 1 
ATOM   3228  N N   . ALA A 1 455 ? 200.711 241.025 121.285 1.00 18.20  ? 487  ALA B N   1 
ATOM   3229  C CA  . ALA A 1 455 ? 200.709 239.883 122.228 1.00 18.20  ? 487  ALA B CA  1 
ATOM   3230  C C   . ALA A 1 455 ? 201.284 238.634 121.556 1.00 18.20  ? 487  ALA B C   1 
ATOM   3231  O O   . ALA A 1 455 ? 200.897 238.316 120.436 1.00 18.20  ? 487  ALA B O   1 
ATOM   3232  C CB  . ALA A 1 455 ? 199.298 239.611 122.759 1.00 24.59  ? 487  ALA B CB  1 
ATOM   3233  N N   . GLU A 1 456 ? 202.212 237.925 122.201 1.00 19.54  ? 488  GLU B N   1 
ATOM   3234  C CA  . GLU A 1 456 ? 202.964 236.822 121.583 1.00 19.54  ? 488  GLU B CA  1 
ATOM   3235  C C   . GLU A 1 456 ? 203.275 235.721 122.590 1.00 19.54  ? 488  GLU B C   1 
ATOM   3236  O O   . GLU A 1 456 ? 203.363 235.976 123.785 1.00 19.54  ? 488  GLU B O   1 
ATOM   3237  C CB  . GLU A 1 456 ? 204.302 237.305 121.009 1.00 25.75  ? 488  GLU B CB  1 
ATOM   3238  C CG  . GLU A 1 456 ? 204.222 238.492 120.043 1.00 25.75  ? 488  GLU B CG  1 
ATOM   3239  C CD  . GLU A 1 456 ? 204.365 239.844 120.752 1.00 25.75  ? 488  GLU B CD  1 
ATOM   3240  O OE1 . GLU A 1 456 ? 205.485 240.154 121.206 1.00 25.75  ? 488  GLU B OE1 1 
ATOM   3241  O OE2 . GLU A 1 456 ? 203.379 240.604 120.849 1.00 25.75  ? 488  GLU B OE2 1 
ATOM   3242  N N   . TYR A 1 457 ? 203.509 234.499 122.116 1.00 16.63  ? 489  TYR B N   1 
ATOM   3243  C CA  . TYR A 1 457 ? 204.011 233.409 122.948 1.00 16.63  ? 489  TYR B CA  1 
ATOM   3244  C C   . TYR A 1 457 ? 205.547 233.491 123.048 1.00 16.63  ? 489  TYR B C   1 
ATOM   3245  O O   . TYR A 1 457 ? 206.268 233.266 122.079 1.00 16.63  ? 489  TYR B O   1 
ATOM   3246  C CB  . TYR A 1 457 ? 203.512 232.071 122.409 1.00 22.32  ? 489  TYR B CB  1 
ATOM   3247  C CG  . TYR A 1 457 ? 202.032 232.047 122.062 1.00 22.32  ? 489  TYR B CG  1 
ATOM   3248  C CD1 . TYR A 1 457 ? 201.070 231.804 123.054 1.00 22.32  ? 489  TYR B CD1 1 
ATOM   3249  C CD2 . TYR A 1 457 ? 201.617 232.210 120.730 1.00 22.32  ? 489  TYR B CD2 1 
ATOM   3250  C CE1 . TYR A 1 457 ? 199.710 231.661 122.709 1.00 22.32  ? 489  TYR B CE1 1 
ATOM   3251  C CE2 . TYR A 1 457 ? 200.272 232.006 120.371 1.00 22.32  ? 489  TYR B CE2 1 
ATOM   3252  C CZ  . TYR A 1 457 ? 199.322 231.695 121.358 1.00 22.32  ? 489  TYR B CZ  1 
ATOM   3253  O OH  . TYR A 1 457 ? 198.071 231.335 120.991 1.00 22.32  ? 489  TYR B OH  1 
ATOM   3254  N N   . LYS A 1 458 ? 206.063 233.866 124.212 1.00 16.39  ? 490  LYS B N   1 
ATOM   3255  C CA  . LYS A 1 458 ? 207.467 234.077 124.489 1.00 16.39  ? 490  LYS B CA  1 
ATOM   3256  C C   . LYS A 1 458 ? 208.096 232.838 125.028 1.00 16.39  ? 490  LYS B C   1 
ATOM   3257  O O   . LYS A 1 458 ? 207.453 232.064 125.708 1.00 16.39  ? 490  LYS B O   1 
ATOM   3258  C CB  . LYS A 1 458 ? 207.627 235.178 125.528 1.00 23.44  ? 490  LYS B CB  1 
ATOM   3259  C CG  . LYS A 1 458 ? 206.994 236.514 125.178 1.00 23.44  ? 490  LYS B CG  1 
ATOM   3260  C CD  . LYS A 1 458 ? 207.622 237.151 123.952 1.00 23.44  ? 490  LYS B CD  1 
ATOM   3261  C CE  . LYS A 1 458 ? 207.124 238.580 123.761 1.00 23.44  ? 490  LYS B CE  1 
ATOM   3262  N NZ  . LYS A 1 458 ? 207.674 239.214 122.523 1.00 23.44  ? 490  LYS B NZ  1 
ATOM   3263  N N   . VAL A 1 459 ? 209.374 232.666 124.825 1.00 17.31  ? 491  VAL B N   1 
ATOM   3264  C CA  . VAL A 1 459 ? 209.993 231.515 125.441 1.00 17.31  ? 491  VAL B CA  1 
ATOM   3265  C C   . VAL A 1 459 ? 210.261 231.771 126.910 1.00 17.31  ? 491  VAL B C   1 
ATOM   3266  O O   . VAL A 1 459 ? 210.854 232.784 127.271 1.00 17.31  ? 491  VAL B O   1 
ATOM   3267  C CB  . VAL A 1 459 ? 211.296 231.155 124.708 1.00 24.38  ? 491  VAL B CB  1 
ATOM   3268  C CG1 . VAL A 1 459 ? 212.040 230.017 125.417 1.00 24.38  ? 491  VAL B CG1 1 
ATOM   3269  C CG2 . VAL A 1 459 ? 210.945 230.716 123.318 1.00 24.38  ? 491  VAL B CG2 1 
ATOM   3270  N N   . ILE A 1 460 ? 209.834 230.836 127.742 1.00 24.06  ? 492  ILE B N   1 
ATOM   3271  C CA  . ILE A 1 460 ? 210.062 230.873 129.173 1.00 24.06  ? 492  ILE B CA  1 
ATOM   3272  C C   . ILE A 1 460 ? 211.324 230.097 129.420 1.00 24.06  ? 492  ILE B C   1 
ATOM   3273  O O   . ILE A 1 460 ? 212.161 230.451 130.258 1.00 24.06  ? 492  ILE B O   1 
ATOM   3274  C CB  . ILE A 1 460 ? 208.944 230.208 129.983 1.00 34.20  ? 492  ILE B CB  1 
ATOM   3275  C CG1 . ILE A 1 460 ? 207.657 230.947 129.806 1.00 34.20  ? 492  ILE B CG1 1 
ATOM   3276  C CG2 . ILE A 1 460 ? 209.355 230.196 131.451 1.00 34.20  ? 492  ILE B CG2 1 
ATOM   3277  C CD1 . ILE A 1 460 ? 206.412 230.223 130.376 1.00 34.20  ? 492  ILE B CD1 1 
ATOM   3278  N N   . GLY A 1 461 ? 211.410 228.972 128.736 1.00 52.02  ? 493  GLY B N   1 
ATOM   3279  C CA  . GLY A 1 461 ? 212.531 228.088 128.926 1.00 52.02  ? 493  GLY B CA  1 
ATOM   3280  C C   . GLY A 1 461 ? 212.352 226.782 128.205 1.00 52.02  ? 493  GLY B C   1 
ATOM   3281  O O   . GLY A 1 461 ? 211.470 226.651 127.361 1.00 52.02  ? 493  GLY B O   1 
ATOM   3282  N N   . SER A 1 462 ? 213.162 225.800 128.566 1.00 28.08  ? 494  SER B N   1 
ATOM   3283  C CA  . SER A 1 462 ? 213.134 224.507 127.864 1.00 28.08  ? 494  SER B CA  1 
ATOM   3284  C C   . SER A 1 462 ? 213.078 223.301 128.783 1.00 28.08  ? 494  SER B C   1 
ATOM   3285  O O   . SER A 1 462 ? 213.217 223.422 130.008 1.00 28.08  ? 494  SER B O   1 
ATOM   3286  C CB  . SER A 1 462 ? 214.357 224.358 126.991 1.00 37.40  ? 494  SER B CB  1 
ATOM   3287  O OG  . SER A 1 462 ? 215.522 224.239 127.767 1.00 37.40  ? 494  SER B OG  1 
ATOM   3288  N N   . TRP A 1 463 ? 212.785 222.130 128.211 1.00 24.98  ? 495  TRP B N   1 
ATOM   3289  C CA  . TRP A 1 463 ? 212.771 220.891 128.971 1.00 24.98  ? 495  TRP B CA  1 
ATOM   3290  C C   . TRP A 1 463 ? 213.322 219.679 128.240 1.00 24.98  ? 495  TRP B C   1 
ATOM   3291  O O   . TRP A 1 463 ? 212.973 219.399 127.092 1.00 24.98  ? 495  TRP B O   1 
ATOM   3292  C CB  . TRP A 1 463 ? 211.359 220.621 129.436 1.00 33.44  ? 495  TRP B CB  1 
ATOM   3293  C CG  . TRP A 1 463 ? 211.121 219.442 130.311 1.00 33.44  ? 495  TRP B CG  1 
ATOM   3294  C CD1 . TRP A 1 463 ? 211.036 219.460 131.654 1.00 33.44  ? 495  TRP B CD1 1 
ATOM   3295  C CD2 . TRP A 1 463 ? 210.851 218.072 129.934 1.00 33.44  ? 495  TRP B CD2 1 
ATOM   3296  N NE1 . TRP A 1 463 ? 210.613 218.239 132.120 1.00 33.44  ? 495  TRP B NE1 1 
ATOM   3297  C CE2 . TRP A 1 463 ? 210.429 217.362 131.090 1.00 33.44  ? 495  TRP B CE2 1 
ATOM   3298  C CE3 . TRP A 1 463 ? 210.875 217.373 128.719 1.00 33.44  ? 495  TRP B CE3 1 
ATOM   3299  C CZ2 . TRP A 1 463 ? 209.975 216.046 131.042 1.00 33.44  ? 495  TRP B CZ2 1 
ATOM   3300  C CZ3 . TRP A 1 463 ? 210.462 216.035 128.664 1.00 33.44  ? 495  TRP B CZ3 1 
ATOM   3301  C CH2 . TRP A 1 463 ? 209.989 215.376 129.813 1.00 33.44  ? 495  TRP B CH2 1 
ATOM   3302  N N   . THR A 1 464 ? 214.127 218.915 128.973 1.00 27.07  ? 496  THR B N   1 
ATOM   3303  C CA  . THR A 1 464 ? 214.632 217.603 128.582 1.00 27.07  ? 496  THR B CA  1 
ATOM   3304  C C   . THR A 1 464 ? 214.687 216.747 129.822 1.00 27.07  ? 496  THR B C   1 
ATOM   3305  O O   . THR A 1 464 ? 215.764 216.579 130.402 1.00 27.07  ? 496  THR B O   1 
ATOM   3306  C CB  . THR A 1 464 ? 216.047 217.652 127.990 1.00 37.06  ? 496  THR B CB  1 
ATOM   3307  O OG1 . THR A 1 464 ? 216.922 218.248 128.939 1.00 37.06  ? 496  THR B OG1 1 
ATOM   3308  C CG2 . THR A 1 464 ? 216.066 218.453 126.715 1.00 37.06  ? 496  THR B CG2 1 
ATOM   3309  N N   . ASP A 1 465 ? 213.529 216.331 130.318 1.00 28.14  ? 497  ASP B N   1 
ATOM   3310  C CA  . ASP A 1 465 ? 213.372 215.597 131.581 1.00 28.14  ? 497  ASP B CA  1 
ATOM   3311  C C   . ASP A 1 465 ? 213.759 216.436 132.798 1.00 28.14  ? 497  ASP B C   1 
ATOM   3312  O O   . ASP A 1 465 ? 213.888 215.929 133.912 1.00 28.14  ? 497  ASP B O   1 
ATOM   3313  C CB  . ASP A 1 465 ? 214.150 214.286 131.538 1.00 35.83  ? 497  ASP B CB  1 
ATOM   3314  C CG  . ASP A 1 465 ? 213.573 213.333 130.494 1.00 35.83  ? 497  ASP B CG  1 
ATOM   3315  O OD1 . ASP A 1 465 ? 212.368 213.180 130.447 1.00 35.83  ? 497  ASP B OD1 1 
ATOM   3316  O OD2 . ASP A 1 465 ? 214.334 212.779 129.739 1.00 35.83  ? 497  ASP B OD2 1 
ATOM   3317  N N   . HIS A 1 466 ? 213.933 217.718 132.561 1.00 30.17  ? 498  HIS B N   1 
ATOM   3318  C CA  . HIS A 1 466 ? 214.265 218.721 133.547 1.00 30.17  ? 498  HIS B CA  1 
ATOM   3319  C C   . HIS A 1 466 ? 213.909 220.096 133.029 1.00 30.17  ? 498  HIS B C   1 
ATOM   3320  O O   . HIS A 1 466 ? 214.118 220.385 131.848 1.00 30.17  ? 498  HIS B O   1 
ATOM   3321  C CB  . HIS A 1 466 ? 215.749 218.701 133.875 1.00 40.07  ? 498  HIS B CB  1 
ATOM   3322  C CG  . HIS A 1 466 ? 216.084 219.630 134.968 1.00 40.07  ? 498  HIS B CG  1 
ATOM   3323  N ND1 . HIS A 1 466 ? 215.811 219.355 136.286 1.00 40.07  ? 498  HIS B ND1 1 
ATOM   3324  C CD2 . HIS A 1 466 ? 216.635 220.851 134.944 1.00 40.07  ? 498  HIS B CD2 1 
ATOM   3325  C CE1 . HIS A 1 466 ? 216.198 220.376 137.029 1.00 40.07  ? 498  HIS B CE1 1 
ATOM   3326  N NE2 . HIS A 1 466 ? 216.699 221.295 136.236 1.00 40.07  ? 498  HIS B NE2 1 
ATOM   3327  N N   . LEU A 1 467 ? 213.366 220.953 133.892 1.00 32.24  ? 499  LEU B N   1 
ATOM   3328  C CA  . LEU A 1 467 ? 213.049 222.322 133.494 1.00 32.24  ? 499  LEU B CA  1 
ATOM   3329  C C   . LEU A 1 467 ? 214.142 223.342 133.665 1.00 32.24  ? 499  LEU B C   1 
ATOM   3330  O O   . LEU A 1 467 ? 214.769 223.462 134.719 1.00 32.24  ? 499  LEU B O   1 
ATOM   3331  C CB  . LEU A 1 467 ? 211.851 222.848 134.278 1.00 45.82  ? 499  LEU B CB  1 
ATOM   3332  C CG  . LEU A 1 467 ? 210.515 222.228 133.998 1.00 45.82  ? 499  LEU B CG  1 
ATOM   3333  C CD1 . LEU A 1 467 ? 209.550 222.692 134.976 1.00 45.82  ? 499  LEU B CD1 1 
ATOM   3334  C CD2 . LEU A 1 467 ? 210.019 222.676 132.607 1.00 45.82  ? 499  LEU B CD2 1 
ATOM   3335  N N   . HIS A 1 468 ? 214.190 224.221 132.685 1.00 31.28  ? 500  HIS B N   1 
ATOM   3336  C CA  . HIS A 1 468 ? 215.081 225.354 132.636 1.00 31.28  ? 500  HIS B CA  1 
ATOM   3337  C C   . HIS A 1 468 ? 214.286 226.625 132.355 1.00 31.28  ? 500  HIS B C   1 
ATOM   3338  O O   . HIS A 1 468 ? 214.408 227.182 131.264 1.00 31.28  ? 500  HIS B O   1 
ATOM   3339  C CB  . HIS A 1 468 ? 216.091 225.138 131.509 1.00 41.55  ? 500  HIS B CB  1 
ATOM   3340  C CG  . HIS A 1 468 ? 216.941 223.910 131.658 1.00 41.55  ? 500  HIS B CG  1 
ATOM   3341  N ND1 . HIS A 1 468 ? 218.058 223.868 132.466 1.00 41.55  ? 500  HIS B ND1 1 
ATOM   3342  C CD2 . HIS A 1 468 ? 216.829 222.674 131.106 1.00 41.55  ? 500  HIS B CD2 1 
ATOM   3343  C CE1 . HIS A 1 468 ? 218.609 222.671 132.392 1.00 41.55  ? 500  HIS B CE1 1 
ATOM   3344  N NE2 . HIS A 1 468 ? 217.886 221.924 131.575 1.00 41.55  ? 500  HIS B NE2 1 
ATOM   3345  N N   . LEU A 1 469 ? 213.429 227.041 133.308 1.00 26.36  ? 501  LEU B N   1 
ATOM   3346  C CA  . LEU A 1 469 ? 212.516 228.180 133.113 1.00 26.36  ? 501  LEU B CA  1 
ATOM   3347  C C   . LEU A 1 469 ? 212.910 229.434 133.871 1.00 26.36  ? 501  LEU B C   1 
ATOM   3348  O O   . LEU A 1 469 ? 213.368 229.345 135.014 1.00 26.36  ? 501  LEU B O   1 
ATOM   3349  C CB  . LEU A 1 469 ? 211.120 227.818 133.626 1.00 37.47  ? 501  LEU B CB  1 
ATOM   3350  C CG  . LEU A 1 469 ? 210.464 226.578 133.067 1.00 37.47  ? 501  LEU B CG  1 
ATOM   3351  C CD1 . LEU A 1 469 ? 209.072 226.444 133.690 1.00 37.47  ? 501  LEU B CD1 1 
ATOM   3352  C CD2 . LEU A 1 469 ? 210.413 226.594 131.580 1.00 37.47  ? 501  LEU B CD2 1 
ATOM   3353  N N   . ARG A 1 470 ? 212.629 230.607 133.285 1.00 28.13  ? 502  ARG B N   1 
ATOM   3354  C CA  . ARG A 1 470 ? 212.819 231.878 133.990 1.00 28.13  ? 502  ARG B CA  1 
ATOM   3355  C C   . ARG A 1 470 ? 211.621 232.828 133.751 1.00 28.13  ? 502  ARG B C   1 
ATOM   3356  O O   . ARG A 1 470 ? 211.188 232.985 132.609 1.00 28.13  ? 502  ARG B O   1 
ATOM   3357  C CB  . ARG A 1 470 ? 214.088 232.562 133.502 1.00 39.51  ? 502  ARG B CB  1 
ATOM   3358  C CG  . ARG A 1 470 ? 215.381 231.787 133.746 1.00 39.51  ? 502  ARG B CG  1 
ATOM   3359  C CD  . ARG A 1 470 ? 215.757 231.705 135.177 1.00 39.51  ? 502  ARG B CD  1 
ATOM   3360  N NE  . ARG A 1 470 ? 217.025 231.029 135.337 1.00 39.51  ? 502  ARG B NE  1 
ATOM   3361  C CZ  . ARG A 1 470 ? 217.192 229.685 135.418 1.00 39.51  ? 502  ARG B CZ  1 
ATOM   3362  N NH1 . ARG A 1 470 ? 218.415 229.196 135.562 1.00 39.51  ? 502  ARG B NH1 1 
ATOM   3363  N NH2 . ARG A 1 470 ? 216.164 228.853 135.357 1.00 39.51  ? 502  ARG B NH2 1 
ATOM   3364  N N   . ILE A 1 471 ? 211.129 233.503 134.821 1.00 21.14  ? 503  ILE B N   1 
ATOM   3365  C CA  . ILE A 1 471 ? 210.022 234.481 134.782 1.00 21.14  ? 503  ILE B CA  1 
ATOM   3366  C C   . ILE A 1 471 ? 210.606 235.864 135.059 1.00 21.14  ? 503  ILE B C   1 
ATOM   3367  O O   . ILE A 1 471 ? 211.402 236.045 135.987 1.00 21.14  ? 503  ILE B O   1 
ATOM   3368  C CB  . ILE A 1 471 ? 208.855 234.115 135.808 1.00 30.05  ? 503  ILE B CB  1 
ATOM   3369  C CG1 . ILE A 1 471 ? 208.254 232.603 135.529 1.00 30.05  ? 503  ILE B CG1 1 
ATOM   3370  C CG2 . ILE A 1 471 ? 207.656 235.190 135.778 1.00 30.05  ? 503  ILE B CG2 1 
ATOM   3371  C CD1 . ILE A 1 471 ? 207.606 232.367 134.104 1.00 30.05  ? 503  ILE B CD1 1 
ATOM   3372  N N   . GLN A 1 481 ? 203.321 239.113 134.105 1.00 62.17  ? 513  GLN B N   1 
ATOM   3373  C CA  . GLN A 1 481 ? 203.603 237.674 134.217 1.00 62.17  ? 513  GLN B CA  1 
ATOM   3374  C C   . GLN A 1 481 ? 202.988 237.012 135.476 1.00 62.17  ? 513  GLN B C   1 
ATOM   3375  O O   . GLN A 1 481 ? 202.975 235.775 135.568 1.00 62.17  ? 513  GLN B O   1 
ATOM   3376  C CB  . GLN A 1 481 ? 205.148 237.396 134.224 1.00 86.65  ? 513  GLN B CB  1 
ATOM   3377  C CG  . GLN A 1 481 ? 205.941 237.772 132.913 1.00 86.65  ? 513  GLN B CG  1 
ATOM   3378  C CD  . GLN A 1 481 ? 207.499 237.371 132.949 1.00 86.65  ? 513  GLN B CD  1 
ATOM   3379  O OE1 . GLN A 1 481 ? 208.275 237.826 133.818 1.00 86.65  ? 513  GLN B OE1 1 
ATOM   3380  N NE2 . GLN A 1 481 ? 207.917 236.484 131.968 1.00 86.65  ? 513  GLN B NE2 1 
ATOM   3381  N N   . GLN A 1 482 ? 202.575 237.879 136.410 1.00 63.60  ? 514  GLN B N   1 
ATOM   3382  C CA  . GLN A 1 482 ? 202.170 237.618 137.794 1.00 63.60  ? 514  GLN B CA  1 
ATOM   3383  C C   . GLN A 1 482 ? 200.654 237.446 137.879 1.00 63.60  ? 514  GLN B C   1 
ATOM   3384  O O   . GLN A 1 482 ? 199.871 238.322 137.504 1.00 63.60  ? 514  GLN B O   1 
ATOM   3385  C CB  . GLN A 1 482 ? 202.671 238.751 138.714 1.00 86.44  ? 514  GLN B CB  1 
ATOM   3386  C CG  . GLN A 1 482 ? 202.089 238.664 140.141 1.00 86.44  ? 514  GLN B CG  1 
ATOM   3387  C CD  . GLN A 1 482 ? 202.801 239.529 141.178 1.00 86.44  ? 514  GLN B CD  1 
ATOM   3388  O OE1 . GLN A 1 482 ? 203.968 239.864 141.077 1.00 86.44  ? 514  GLN B OE1 1 
ATOM   3389  N NE2 . GLN A 1 482 ? 202.136 239.905 142.247 1.00 86.44  ? 514  GLN B NE2 1 
ATOM   3390  N N   . LEU A 1 483 ? 200.270 236.266 138.346 1.00 52.96  ? 515  LEU B N   1 
ATOM   3391  C CA  . LEU A 1 483 ? 199.023 235.583 138.012 1.00 52.96  ? 515  LEU B CA  1 
ATOM   3392  C C   . LEU A 1 483 ? 198.701 234.532 139.129 1.00 52.96  ? 515  LEU B C   1 
ATOM   3393  O O   . LEU A 1 483 ? 199.544 234.315 140.009 1.00 52.96  ? 515  LEU B O   1 
ATOM   3394  C CB  . LEU A 1 483 ? 199.266 234.998 136.603 1.00 75.27  ? 515  LEU B CB  1 
ATOM   3395  C CG  . LEU A 1 483 ? 199.295 235.967 135.410 1.00 75.27  ? 515  LEU B CG  1 
ATOM   3396  C CD1 . LEU A 1 483 ? 199.773 235.224 134.177 1.00 75.27  ? 515  LEU B CD1 1 
ATOM   3397  C CD2 . LEU A 1 483 ? 197.918 236.564 135.151 1.00 75.27  ? 515  LEU B CD2 1 
ATOM   3398  N N   . PRO A 1 484 ? 197.482 233.950 139.205 1.00 51.96  ? 516  PRO B N   1 
ATOM   3399  C CA  . PRO A 1 484 ? 196.948 233.340 140.440 1.00 51.96  ? 516  PRO B CA  1 
ATOM   3400  C C   . PRO A 1 484 ? 197.515 231.944 140.759 1.00 51.96  ? 516  PRO B C   1 
ATOM   3401  O O   . PRO A 1 484 ? 198.315 231.410 140.001 1.00 51.96  ? 516  PRO B O   1 
ATOM   3402  C CB  . PRO A 1 484 ? 195.434 233.320 140.224 1.00 88.79  ? 516  PRO B CB  1 
ATOM   3403  C CG  . PRO A 1 484 ? 195.305 233.088 138.720 1.00 88.79  ? 516  PRO B CG  1 
ATOM   3404  C CD  . PRO A 1 484 ? 196.446 233.949 138.175 1.00 88.79  ? 516  PRO B CD  1 
ATOM   3405  N N   . ARG A 1 485 ? 197.144 231.345 141.904 1.00 39.72  ? 517  ARG B N   1 
ATOM   3406  C CA  . ARG A 1 485 ? 197.824 230.137 142.431 1.00 39.72  ? 517  ARG B CA  1 
ATOM   3407  C C   . ARG A 1 485 ? 196.873 229.005 142.854 1.00 39.72  ? 517  ARG B C   1 
ATOM   3408  O O   . ARG A 1 485 ? 195.790 229.256 143.372 1.00 39.72  ? 517  ARG B O   1 
ATOM   3409  C CB  . ARG A 1 485 ? 198.827 230.552 143.525 1.00 55.78  ? 517  ARG B CB  1 
ATOM   3410  C CG  . ARG A 1 485 ? 199.831 231.584 142.970 1.00 55.78  ? 517  ARG B CG  1 
ATOM   3411  C CD  . ARG A 1 485 ? 200.916 231.977 143.966 1.00 55.78  ? 517  ARG B CD  1 
ATOM   3412  N NE  . ARG A 1 485 ? 201.877 232.913 143.347 1.00 55.78  ? 517  ARG B NE  1 
ATOM   3413  C CZ  . ARG A 1 485 ? 201.746 234.217 143.190 1.00 55.78  ? 517  ARG B CZ  1 
ATOM   3414  N NH1 . ARG A 1 485 ? 202.695 234.900 142.619 1.00 55.78  ? 517  ARG B NH1 1 
ATOM   3415  N NH2 . ARG A 1 485 ? 200.700 234.874 143.598 1.00 55.78  ? 517  ARG B NH2 1 
ATOM   3416  N N   . SER A 1 486 ? 197.273 227.757 142.597 1.00 37.48  ? 518  SER B N   1 
ATOM   3417  C CA  . SER A 1 486 ? 196.362 226.597 142.471 1.00 37.48  ? 518  SER B CA  1 
ATOM   3418  C C   . SER A 1 486 ? 196.837 225.478 143.382 1.00 37.48  ? 518  SER B C   1 
ATOM   3419  O O   . SER A 1 486 ? 197.664 224.659 143.012 1.00 37.48  ? 518  SER B O   1 
ATOM   3420  C CB  . SER A 1 486 ? 196.333 226.149 141.012 1.00 49.92  ? 518  SER B CB  1 
ATOM   3421  O OG  . SER A 1 486 ? 196.101 227.266 140.186 1.00 49.92  ? 518  SER B OG  1 
ATOM   3422  N N   . ILE A 1 487 ? 196.357 225.471 144.618 1.00 46.32  ? 519  ILE B N   1 
ATOM   3423  C CA  . ILE A 1 487 ? 197.144 224.898 145.714 1.00 46.32  ? 519  ILE B CA  1 
ATOM   3424  C C   . ILE A 1 487 ? 196.429 224.089 146.803 1.00 46.32  ? 519  ILE B C   1 
ATOM   3425  O O   . ILE A 1 487 ? 197.117 223.561 147.672 1.00 46.32  ? 519  ILE B O   1 
ATOM   3426  C CB  . ILE A 1 487 ? 197.965 226.060 146.330 1.00 65.84  ? 519  ILE B CB  1 
ATOM   3427  C CG1 . ILE A 1 487 ? 197.137 227.223 146.925 1.00 65.84  ? 519  ILE B CG1 1 
ATOM   3428  C CG2 . ILE A 1 487 ? 198.896 226.661 145.264 1.00 65.84  ? 519  ILE B CG2 1 
ATOM   3429  C CD1 . ILE A 1 487 ? 197.946 228.252 147.716 1.00 65.84  ? 519  ILE B CD1 1 
ATOM   3430  N N   . CYS A 1 488 ? 195.113 223.899 146.764 1.00 65.87  ? 520  CYS B N   1 
ATOM   3431  C CA  . CYS A 1 488 ? 194.375 223.218 147.847 1.00 65.87  ? 520  CYS B CA  1 
ATOM   3432  C C   . CYS A 1 488 ? 194.462 223.961 149.200 1.00 65.87  ? 520  CYS B C   1 
ATOM   3433  O O   . CYS A 1 488 ? 194.511 225.187 149.223 1.00 65.87  ? 520  CYS B O   1 
ATOM   3434  C CB  . CYS A 1 488 ? 194.741 221.728 147.952 1.00 87.74  ? 520  CYS B CB  1 
ATOM   3435  S SG  . CYS A 1 488 ? 193.376 220.769 148.657 1.00 87.74  ? 520  CYS B SG  1 
ATOM   3436  N N   . SER A 1 489 ? 194.413 223.230 150.318 1.00 71.84  ? 521  SER B N   1 
ATOM   3437  C CA  . SER A 1 489 ? 194.332 223.772 151.675 1.00 71.84  ? 521  SER B CA  1 
ATOM   3438  C C   . SER A 1 489 ? 195.442 224.770 151.986 1.00 71.84  ? 521  SER B C   1 
ATOM   3439  O O   . SER A 1 489 ? 196.581 224.626 151.546 1.00 71.84  ? 521  SER B O   1 
ATOM   3440  C CB  . SER A 1 489 ? 194.393 222.643 152.699 1.00 95.69  ? 521  SER B CB  1 
ATOM   3441  O OG  . SER A 1 489 ? 193.294 221.773 152.540 1.00 95.69  ? 521  SER B OG  1 
ATOM   3442  N N   . LEU A 1 490 ? 195.101 225.786 152.768 1.00 71.84  ? 522  LEU B N   1 
ATOM   3443  C CA  . LEU A 1 490 ? 196.046 226.810 153.194 1.00 71.84  ? 522  LEU B CA  1 
ATOM   3444  C C   . LEU A 1 490 ? 196.768 226.392 154.476 1.00 71.84  ? 522  LEU B C   1 
ATOM   3445  O O   . LEU A 1 490 ? 196.190 225.654 155.271 1.00 71.84  ? 522  LEU B O   1 
ATOM   3446  C CB  . LEU A 1 490 ? 195.313 228.139 153.381 1.00 105.52 ? 522  LEU B CB  1 
ATOM   3447  C CG  . LEU A 1 490 ? 194.550 228.596 152.129 1.00 105.52 ? 522  LEU B CG  1 
ATOM   3448  C CD1 . LEU A 1 490 ? 193.938 229.964 152.398 1.00 105.52 ? 522  LEU B CD1 1 
ATOM   3449  C CD2 . LEU A 1 490 ? 195.451 228.701 150.899 1.00 105.52 ? 522  LEU B CD2 1 
ATOM   3450  N N   . PRO A 1 491 ? 198.010 226.843 154.702 1.00 81.89  ? 523  PRO B N   1 
ATOM   3451  C CA  . PRO A 1 491 ? 198.757 226.595 155.931 1.00 81.89  ? 523  PRO B CA  1 
ATOM   3452  C C   . PRO A 1 491 ? 198.004 226.935 157.221 1.00 81.89  ? 523  PRO B C   1 
ATOM   3453  O O   . PRO A 1 491 ? 197.035 227.693 157.226 1.00 81.89  ? 523  PRO B O   1 
ATOM   3454  C CB  . PRO A 1 491 ? 200.027 227.437 155.815 1.00 139.93 ? 523  PRO B CB  1 
ATOM   3455  C CG  . PRO A 1 491 ? 200.245 227.519 154.312 1.00 139.93 ? 523  PRO B CG  1 
ATOM   3456  C CD  . PRO A 1 491 ? 198.827 227.590 153.764 1.00 139.93 ? 523  PRO B CD  1 
ATOM   3457  N N   . CYS A 1 492 ? 198.489 226.383 158.332 1.00 90.70  ? 524  CYS B N   1 
ATOM   3458  C CA  . CYS A 1 492 ? 197.776 226.315 159.607 1.00 90.70  ? 524  CYS B CA  1 
ATOM   3459  C C   . CYS A 1 492 ? 198.554 226.954 160.767 1.00 90.70  ? 524  CYS B C   1 
ATOM   3460  O O   . CYS A 1 492 ? 199.785 226.933 160.807 1.00 90.70  ? 524  CYS B O   1 
ATOM   3461  C CB  . CYS A 1 492 ? 197.505 224.846 159.917 1.00 117.53 ? 524  CYS B CB  1 
ATOM   3462  S SG  . CYS A 1 492 ? 196.827 223.858 158.568 1.00 117.53 ? 524  CYS B SG  1 
ATOM   3463  N N   . GLN A 1 493 ? 197.844 227.492 161.748 1.00 90.52  ? 525  GLN B N   1 
ATOM   3464  C CA  . GLN A 1 493 ? 198.430 228.169 162.907 1.00 90.52  ? 525  GLN B CA  1 
ATOM   3465  C C   . GLN A 1 493 ? 199.198 227.233 163.849 1.00 90.52  ? 525  GLN B C   1 
ATOM   3466  O O   . GLN A 1 493 ? 199.038 226.011 163.786 1.00 90.52  ? 525  GLN B O   1 
ATOM   3467  C CB  . GLN A 1 493 ? 197.301 228.864 163.685 1.00 123.03 ? 525  GLN B CB  1 
ATOM   3468  C CG  . GLN A 1 493 ? 196.643 229.993 162.885 1.00 123.03 ? 525  GLN B CG  1 
ATOM   3469  C CD  . GLN A 1 493 ? 197.612 231.103 162.493 1.00 123.03 ? 525  GLN B CD  1 
ATOM   3470  O OE1 . GLN A 1 493 ? 198.648 231.324 163.101 1.00 123.03 ? 525  GLN B OE1 1 
ATOM   3471  N NE2 . GLN A 1 493 ? 197.323 231.844 161.452 1.00 123.03 ? 525  GLN B NE2 1 
ATOM   3472  N N   . PRO A 1 494 ? 200.005 227.760 164.782 1.00 88.37  ? 526  PRO B N   1 
ATOM   3473  C CA  . PRO A 1 494 ? 200.442 227.005 165.952 1.00 88.37  ? 526  PRO B CA  1 
ATOM   3474  C C   . PRO A 1 494 ? 199.250 226.339 166.642 1.00 88.37  ? 526  PRO B C   1 
ATOM   3475  O O   . PRO A 1 494 ? 198.170 226.921 166.734 1.00 88.37  ? 526  PRO B O   1 
ATOM   3476  C CB  . PRO A 1 494 ? 201.119 228.016 166.874 1.00 151.00 ? 526  PRO B CB  1 
ATOM   3477  C CG  . PRO A 1 494 ? 201.589 229.101 165.910 1.00 151.00 ? 526  PRO B CG  1 
ATOM   3478  C CD  . PRO A 1 494 ? 200.484 229.126 164.859 1.00 151.00 ? 526  PRO B CD  1 
ATOM   3479  N N   . GLY A 1 495 ? 199.419 225.091 167.068 1.00 88.93  ? 527  GLY B N   1 
ATOM   3480  C CA  . GLY A 1 495 ? 198.349 224.283 167.653 1.00 88.93  ? 527  GLY B CA  1 
ATOM   3481  C C   . GLY A 1 495 ? 197.345 223.707 166.648 1.00 88.93  ? 527  GLY B C   1 
ATOM   3482  O O   . GLY A 1 495 ? 196.673 222.734 166.975 1.00 88.93  ? 527  GLY B O   1 
ATOM   3483  N N   . GLU A 1 496 ? 197.236 224.220 165.424 1.00 92.27  ? 528  GLU B N   1 
ATOM   3484  C CA  . GLU A 1 496 ? 196.357 223.642 164.400 1.00 92.27  ? 528  GLU B CA  1 
ATOM   3485  C C   . GLU A 1 496 ? 196.962 222.379 163.792 1.00 92.27  ? 528  GLU B C   1 
ATOM   3486  O O   . GLU A 1 496 ? 197.548 222.403 162.709 1.00 92.27  ? 528  GLU B O   1 
ATOM   3487  C CB  . GLU A 1 496 ? 195.985 224.682 163.347 1.00 121.60 ? 528  GLU B CB  1 
ATOM   3488  C CG  . GLU A 1 496 ? 195.008 225.696 163.938 1.00 121.60 ? 528  GLU B CG  1 
ATOM   3489  C CD  . GLU A 1 496 ? 194.490 226.693 162.895 1.00 121.60 ? 528  GLU B CD  1 
ATOM   3490  O OE1 . GLU A 1 496 ? 195.155 226.917 161.859 1.00 121.60 ? 528  GLU B OE1 1 
ATOM   3491  O OE2 . GLU A 1 496 ? 193.430 227.307 163.153 1.00 121.60 ? 528  GLU B OE2 1 
ATOM   3492  N N   . ARG A 1 497 ? 196.852 221.259 164.506 1.00 91.51  ? 529  ARG B N   1 
ATOM   3493  C CA  . ARG A 1 497 ? 197.278 219.960 163.997 1.00 91.51  ? 529  ARG B CA  1 
ATOM   3494  C C   . ARG A 1 497 ? 196.489 219.606 162.728 1.00 91.51  ? 529  ARG B C   1 
ATOM   3495  O O   . ARG A 1 497 ? 195.279 219.398 162.744 1.00 91.51  ? 529  ARG B O   1 
ATOM   3496  C CB  . ARG A 1 497 ? 197.235 218.885 165.094 1.00 128.52 ? 529  ARG B CB  1 
ATOM   3497  C CG  . ARG A 1 497 ? 195.850 218.564 165.690 1.00 128.52 ? 529  ARG B CG  1 
ATOM   3498  C CD  . ARG A 1 497 ? 195.796 217.200 166.389 1.00 128.52 ? 529  ARG B CD  1 
ATOM   3499  N NE  . ARG A 1 497 ? 196.202 216.084 165.500 1.00 128.52 ? 529  ARG B NE  1 
ATOM   3500  C CZ  . ARG A 1 497 ? 196.217 214.793 165.785 1.00 128.52 ? 529  ARG B CZ  1 
ATOM   3501  N NH1 . ARG A 1 497 ? 196.669 213.945 164.920 1.00 128.52 ? 529  ARG B NH1 1 
ATOM   3502  N NH2 . ARG A 1 497 ? 195.833 214.333 166.932 1.00 128.52 ? 529  ARG B NH2 1 
ATOM   3503  N N   . LYS A 1 498 ? 197.180 219.544 161.594 1.00 92.07  ? 530  LYS B N   1 
ATOM   3504  C CA  . LYS A 1 498 ? 196.574 219.151 160.326 1.00 92.07  ? 530  LYS B CA  1 
ATOM   3505  C C   . LYS A 1 498 ? 195.931 217.776 160.470 1.00 92.07  ? 530  LYS B C   1 
ATOM   3506  O O   . LYS A 1 498 ? 196.528 216.860 161.030 1.00 92.07  ? 530  LYS B O   1 
ATOM   3507  C CB  . LYS A 1 498 ? 197.601 219.141 159.186 1.00 131.70 ? 530  LYS B CB  1 
ATOM   3508  C CG  . LYS A 1 498 ? 197.982 220.537 158.696 1.00 131.70 ? 530  LYS B CG  1 
ATOM   3509  C CD  . LYS A 1 498 ? 198.883 220.448 157.456 1.00 131.70 ? 530  LYS B CD  1 
ATOM   3510  C CE  . LYS A 1 498 ? 199.276 221.843 156.948 1.00 131.70 ? 530  LYS B CE  1 
ATOM   3511  N NZ  . LYS A 1 498 ? 200.071 221.774 155.690 1.00 131.70 ? 530  LYS B NZ  1 
ATOM   3512  N N   . LYS A 1 499 ? 194.734 217.617 159.925 1.00 91.04  ? 531  LYS B N   1 
ATOM   3513  C CA  . LYS A 1 499 ? 194.181 216.314 159.549 1.00 91.04  ? 531  LYS B CA  1 
ATOM   3514  C C   . LYS A 1 499 ? 194.176 216.273 158.037 1.00 91.04  ? 531  LYS B C   1 
ATOM   3515  O O   . LYS A 1 499 ? 193.736 217.242 157.428 1.00 91.04  ? 531  LYS B O   1 
ATOM   3516  C CB  . LYS A 1 499 ? 192.761 216.132 160.095 1.00 130.23 ? 531  LYS B CB  1 
ATOM   3517  C CG  . LYS A 1 499 ? 192.579 216.498 161.567 1.00 130.23 ? 531  LYS B CG  1 
ATOM   3518  C CD  . LYS A 1 499 ? 193.456 215.730 162.559 1.00 130.23 ? 531  LYS B CD  1 
ATOM   3519  C CE  . LYS A 1 499 ? 193.290 216.284 163.980 1.00 130.23 ? 531  LYS B CE  1 
ATOM   3520  N NZ  . LYS A 1 499 ? 191.915 216.106 164.512 1.00 130.23 ? 531  LYS B NZ  1 
ATOM   3521  N N   . THR A 1 500 ? 194.674 215.222 157.406 1.00 89.09  ? 532  THR B N   1 
ATOM   3522  C CA  . THR A 1 500 ? 194.646 215.141 155.937 1.00 89.09  ? 532  THR B CA  1 
ATOM   3523  C C   . THR A 1 500 ? 193.195 215.205 155.453 1.00 89.09  ? 532  THR B C   1 
ATOM   3524  O O   . THR A 1 500 ? 192.307 214.603 156.055 1.00 89.09  ? 532  THR B O   1 
ATOM   3525  C CB  . THR A 1 500 ? 195.325 213.858 155.434 1.00 121.95 ? 532  THR B CB  1 
ATOM   3526  O OG1 . THR A 1 500 ? 196.587 213.695 156.042 1.00 121.95 ? 532  THR B OG1 1 
ATOM   3527  C CG2 . THR A 1 500 ? 195.572 213.863 153.929 1.00 121.95 ? 532  THR B CG2 1 
ATOM   3528  N N   . VAL A 1 501 ? 192.929 215.953 154.384 1.00 87.16  ? 533  VAL B N   1 
ATOM   3529  C CA  . VAL A 1 501 ? 191.639 215.887 153.683 1.00 87.16  ? 533  VAL B CA  1 
ATOM   3530  C C   . VAL A 1 501 ? 191.605 214.536 152.981 1.00 87.16  ? 533  VAL B C   1 
ATOM   3531  O O   . VAL A 1 501 ? 192.408 214.305 152.081 1.00 87.16  ? 533  VAL B O   1 
ATOM   3532  C CB  . VAL A 1 501 ? 191.513 217.064 152.704 1.00 122.74 ? 533  VAL B CB  1 
ATOM   3533  C CG1 . VAL A 1 501 ? 190.516 216.853 151.561 1.00 122.74 ? 533  VAL B CG1 1 
ATOM   3534  C CG2 . VAL A 1 501 ? 191.102 218.335 153.450 1.00 122.74 ? 533  VAL B CG2 1 
ATOM   3535  N N   . LYS A 1 502 ? 190.741 213.618 153.429 1.00 82.50  ? 534  LYS B N   1 
ATOM   3536  C CA  . LYS A 1 502 ? 190.773 212.197 153.033 1.00 82.50  ? 534  LYS B CA  1 
ATOM   3537  C C   . LYS A 1 502 ? 192.213 211.650 153.132 1.00 82.50  ? 534  LYS B C   1 
ATOM   3538  O O   . LYS A 1 502 ? 192.882 211.867 154.138 1.00 82.50  ? 534  LYS B O   1 
ATOM   3539  C CB  . LYS A 1 502 ? 190.088 212.059 151.659 1.00 118.01 ? 534  LYS B CB  1 
ATOM   3540  C CG  . LYS A 1 502 ? 189.605 210.631 151.385 1.00 118.01 ? 534  LYS B CG  1 
ATOM   3541  C CD  . LYS A 1 502 ? 189.148 210.516 149.934 1.00 118.01 ? 534  LYS B CD  1 
ATOM   3542  C CE  . LYS A 1 502 ? 188.625 209.109 149.667 1.00 118.01 ? 534  LYS B CE  1 
ATOM   3543  N NZ  . LYS A 1 502 ? 188.207 208.940 148.259 1.00 118.01 ? 534  LYS B NZ  1 
ATOM   3544  N N   . GLY A 1 503 ? 192.717 210.992 152.091 1.00 81.06  ? 535  GLY B N   1 
ATOM   3545  C CA  . GLY A 1 503 ? 194.139 210.690 151.917 1.00 81.06  ? 535  GLY B CA  1 
ATOM   3546  C C   . GLY A 1 503 ? 194.858 211.657 150.969 1.00 81.06  ? 535  GLY B C   1 
ATOM   3547  O O   . GLY A 1 503 ? 195.963 211.349 150.531 1.00 81.06  ? 535  GLY B O   1 
ATOM   3548  N N   . MET A 1 504 ? 194.245 212.785 150.595 1.00 82.11  ? 536  MET B N   1 
ATOM   3549  C CA  . MET A 1 504 ? 194.710 213.641 149.497 1.00 82.11  ? 536  MET B CA  1 
ATOM   3550  C C   . MET A 1 504 ? 196.004 214.368 149.880 1.00 82.11  ? 536  MET B C   1 
ATOM   3551  O O   . MET A 1 504 ? 195.973 215.230 150.762 1.00 82.11  ? 536  MET B O   1 
ATOM   3552  C CB  . MET A 1 504 ? 193.630 214.644 149.066 1.00 114.23 ? 536  MET B CB  1 
ATOM   3553  C CG  . MET A 1 504 ? 192.261 214.008 148.796 1.00 114.23 ? 536  MET B CG  1 
ATOM   3554  S SD  . MET A 1 504 ? 192.270 212.337 148.089 1.00 114.23 ? 536  MET B SD  1 
ATOM   3555  C CE  . MET A 1 504 ? 193.012 212.694 146.472 1.00 114.23 ? 536  MET B CE  1 
ATOM   3556  N N   . PRO A 1 505 ? 197.146 214.056 149.242 1.00 81.93  ? 537  PRO B N   1 
ATOM   3557  C CA  . PRO A 1 505 ? 198.455 214.453 149.751 1.00 81.93  ? 537  PRO B CA  1 
ATOM   3558  C C   . PRO A 1 505 ? 198.613 215.954 149.974 1.00 81.93  ? 537  PRO B C   1 
ATOM   3559  O O   . PRO A 1 505 ? 199.241 216.379 150.938 1.00 81.93  ? 537  PRO B O   1 
ATOM   3560  C CB  . PRO A 1 505 ? 199.461 213.970 148.708 1.00 30.00  ? 537  PRO B CB  1 
ATOM   3561  C CG  . PRO A 1 505 ? 198.773 212.775 148.069 1.00 30.00  ? 537  PRO B CG  1 
ATOM   3562  C CD  . PRO A 1 505 ? 197.303 213.167 148.096 1.00 30.00  ? 537  PRO B CD  1 
ATOM   3563  N N   . CYS A 1 506 ? 198.038 216.763 149.089 1.00 87.61  ? 538  CYS B N   1 
ATOM   3564  C CA  . CYS A 1 506 ? 198.209 218.209 149.094 1.00 87.61  ? 538  CYS B CA  1 
ATOM   3565  C C   . CYS A 1 506 ? 197.167 218.970 149.942 1.00 87.61  ? 538  CYS B C   1 
ATOM   3566  O O   . CYS A 1 506 ? 197.084 220.193 149.840 1.00 87.61  ? 538  CYS B O   1 
ATOM   3567  C CB  . CYS A 1 506 ? 198.264 218.689 147.640 1.00 116.69 ? 538  CYS B CB  1 
ATOM   3568  S SG  . CYS A 1 506 ? 196.695 218.693 146.741 1.00 116.69 ? 538  CYS B SG  1 
ATOM   3569  N N   . CYS A 1 507 ? 196.358 218.283 150.756 1.00 91.28  ? 539  CYS B N   1 
ATOM   3570  C CA  . CYS A 1 507 ? 195.165 218.874 151.361 1.00 91.28  ? 539  CYS B CA  1 
ATOM   3571  C C   . CYS A 1 507 ? 194.947 218.445 152.818 1.00 91.28  ? 539  CYS B C   1 
ATOM   3572  O O   . CYS A 1 507 ? 195.246 217.324 153.224 1.00 91.28  ? 539  CYS B O   1 
ATOM   3573  C CB  . CYS A 1 507 ? 193.960 218.462 150.518 1.00 121.58 ? 539  CYS B CB  1 
ATOM   3574  S SG  . CYS A 1 507 ? 194.007 218.843 148.755 1.00 121.58 ? 539  CYS B SG  1 
ATOM   3575  N N   . TRP A 1 508 ? 194.360 219.331 153.613 1.00 91.84  ? 540  TRP B N   1 
ATOM   3576  C CA  . TRP A 1 508 ? 194.152 219.140 155.043 1.00 91.84  ? 540  TRP B CA  1 
ATOM   3577  C C   . TRP A 1 508 ? 193.086 220.067 155.627 1.00 91.84  ? 540  TRP B C   1 
ATOM   3578  O O   . TRP A 1 508 ? 192.701 221.080 155.040 1.00 91.84  ? 540  TRP B O   1 
ATOM   3579  C CB  . TRP A 1 508 ? 195.466 219.387 155.784 1.00 122.96 ? 540  TRP B CB  1 
ATOM   3580  C CG  . TRP A 1 508 ? 196.029 220.729 155.486 1.00 122.96 ? 540  TRP B CG  1 
ATOM   3581  C CD1 . TRP A 1 508 ? 195.650 221.886 156.067 1.00 122.96 ? 540  TRP B CD1 1 
ATOM   3582  C CD2 . TRP A 1 508 ? 196.976 221.091 154.449 1.00 122.96 ? 540  TRP B CD2 1 
ATOM   3583  N NE1 . TRP A 1 508 ? 196.315 222.931 155.467 1.00 122.96 ? 540  TRP B NE1 1 
ATOM   3584  C CE2 . TRP A 1 508 ? 197.156 222.502 154.478 1.00 122.96 ? 540  TRP B CE2 1 
ATOM   3585  C CE3 . TRP A 1 508 ? 197.716 220.365 153.497 1.00 122.96 ? 540  TRP B CE3 1 
ATOM   3586  C CZ2 . TRP A 1 508 ? 198.042 223.165 153.627 1.00 122.96 ? 540  TRP B CZ2 1 
ATOM   3587  C CZ3 . TRP A 1 508 ? 198.585 221.028 152.613 1.00 122.96 ? 540  TRP B CZ3 1 
ATOM   3588  C CH2 . TRP A 1 508 ? 198.746 222.422 152.671 1.00 122.96 ? 540  TRP B CH2 1 
ATOM   3589  N N   . HIS A 1 509 ? 192.678 219.722 156.836 1.00 91.51  ? 541  HIS B N   1 
ATOM   3590  C CA  . HIS A 1 509 ? 191.933 220.539 157.775 1.00 91.51  ? 541  HIS B CA  1 
ATOM   3591  C C   . HIS A 1 509 ? 192.900 221.028 158.848 1.00 91.51  ? 541  HIS B C   1 
ATOM   3592  O O   . HIS A 1 509 ? 193.600 220.217 159.450 1.00 91.51  ? 541  HIS B O   1 
ATOM   3593  C CB  . HIS A 1 509 ? 190.853 219.662 158.405 1.00 121.55 ? 541  HIS B CB  1 
ATOM   3594  C CG  . HIS A 1 509 ? 190.046 218.907 157.391 1.00 121.55 ? 541  HIS B CG  1 
ATOM   3595  N ND1 . HIS A 1 509 ? 189.095 219.473 156.546 1.00 121.55 ? 541  HIS B ND1 1 
ATOM   3596  C CD2 . HIS A 1 509 ? 190.130 217.572 157.141 1.00 121.55 ? 541  HIS B CD2 1 
ATOM   3597  C CE1 . HIS A 1 509 ? 188.599 218.457 155.828 1.00 121.55 ? 541  HIS B CE1 1 
ATOM   3598  N NE2 . HIS A 1 509 ? 189.202 217.306 156.164 1.00 121.55 ? 541  HIS B NE2 1 
ATOM   3599  N N   . CYS A 1 510 ? 192.974 222.334 159.083 1.00 92.62  ? 542  CYS B N   1 
ATOM   3600  C CA  . CYS A 1 510 ? 193.869 222.948 160.068 1.00 92.62  ? 542  CYS B CA  1 
ATOM   3601  C C   . CYS A 1 510 ? 193.313 222.849 161.500 1.00 92.62  ? 542  CYS B C   1 
ATOM   3602  O O   . CYS A 1 510 ? 192.922 223.851 162.093 1.00 92.62  ? 542  CYS B O   1 
ATOM   3603  C CB  . CYS A 1 510 ? 194.092 224.414 159.673 1.00 120.02 ? 542  CYS B CB  1 
ATOM   3604  S SG  . CYS A 1 510 ? 195.034 224.711 158.163 1.00 120.02 ? 542  CYS B SG  1 
ATOM   3605  N N   . GLU A 1 511 ? 193.190 221.648 162.057 1.00 90.63  ? 543  GLU B N   1 
ATOM   3606  C CA  . GLU A 1 511 ? 192.374 221.472 163.259 1.00 90.63  ? 543  GLU B CA  1 
ATOM   3607  C C   . GLU A 1 511 ? 193.090 221.890 164.550 1.00 90.63  ? 543  GLU B C   1 
ATOM   3608  O O   . GLU A 1 511 ? 194.101 221.293 164.914 1.00 90.63  ? 543  GLU B O   1 
ATOM   3609  C CB  . GLU A 1 511 ? 191.846 220.046 163.351 1.00 119.44 ? 543  GLU B CB  1 
ATOM   3610  C CG  . GLU A 1 511 ? 190.981 219.744 162.120 1.00 119.44 ? 543  GLU B CG  1 
ATOM   3611  C CD  . GLU A 1 511 ? 190.095 218.508 162.286 1.00 119.44 ? 543  GLU B CD  1 
ATOM   3612  O OE1 . GLU A 1 511 ? 190.168 217.830 163.336 1.00 119.44 ? 543  GLU B OE1 1 
ATOM   3613  O OE2 . GLU A 1 511 ? 189.330 218.201 161.347 1.00 119.44 ? 543  GLU B OE2 1 
ATOM   3614  N N   . PRO A 1 512 ? 192.567 222.887 165.283 1.00 90.73  ? 544  PRO B N   1 
ATOM   3615  C CA  . PRO A 1 512 ? 193.166 223.348 166.521 1.00 90.73  ? 544  PRO B CA  1 
ATOM   3616  C C   . PRO A 1 512 ? 193.132 222.248 167.575 1.00 90.73  ? 544  PRO B C   1 
ATOM   3617  O O   . PRO A 1 512 ? 192.127 221.573 167.790 1.00 90.73  ? 544  PRO B O   1 
ATOM   3618  C CB  . PRO A 1 512 ? 192.390 224.592 166.934 1.00 155.04 ? 544  PRO B CB  1 
ATOM   3619  C CG  . PRO A 1 512 ? 191.020 224.374 166.313 1.00 155.04 ? 544  PRO B CG  1 
ATOM   3620  C CD  . PRO A 1 512 ? 191.344 223.629 165.024 1.00 155.04 ? 544  PRO B CD  1 
ATOM   3621  N N   . CYS A 1 513 ? 194.270 222.058 168.221 1.00 90.83  ? 545  CYS B N   1 
ATOM   3622  C CA  . CYS A 1 513 ? 194.428 221.149 169.339 1.00 90.83  ? 545  CYS B CA  1 
ATOM   3623  C C   . CYS A 1 513 ? 193.652 221.634 170.586 1.00 90.83  ? 545  CYS B C   1 
ATOM   3624  O O   . CYS A 1 513 ? 193.184 222.772 170.649 1.00 90.83  ? 545  CYS B O   1 
ATOM   3625  C CB  . CYS A 1 513 ? 195.929 220.941 169.525 1.00 117.70 ? 545  CYS B CB  1 
ATOM   3626  S SG  . CYS A 1 513 ? 196.336 219.851 170.881 1.00 117.70 ? 545  CYS B SG  1 
ATOM   3627  N N   . THR A 1 514 ? 193.459 220.753 171.569 1.00 88.78  ? 546  THR B N   1 
ATOM   3628  C CA  . THR A 1 514 ? 192.397 220.861 172.583 1.00 88.78  ? 546  THR B CA  1 
ATOM   3629  C C   . THR A 1 514 ? 192.811 220.331 173.956 1.00 88.78  ? 546  THR B C   1 
ATOM   3630  O O   . THR A 1 514 ? 193.747 219.545 174.082 1.00 88.78  ? 546  THR B O   1 
ATOM   3631  C CB  . THR A 1 514 ? 191.154 220.078 172.132 1.00 121.53 ? 546  THR B CB  1 
ATOM   3632  O OG1 . THR A 1 514 ? 191.472 218.713 171.946 1.00 121.53 ? 546  THR B OG1 1 
ATOM   3633  C CG2 . THR A 1 514 ? 190.562 220.586 170.821 1.00 121.53 ? 546  THR B CG2 1 
ATOM   3634  N N   . GLY A 1 515 ? 192.083 220.720 175.005 1.00 86.53  ? 547  GLY B N   1 
ATOM   3635  C CA  . GLY A 1 515 ? 192.262 220.179 176.357 1.00 86.53  ? 547  GLY B CA  1 
ATOM   3636  C C   . GLY A 1 515 ? 193.693 220.342 176.852 1.00 86.53  ? 547  GLY B C   1 
ATOM   3637  O O   . GLY A 1 515 ? 194.331 221.362 176.599 1.00 86.53  ? 547  GLY B O   1 
ATOM   3638  N N   . TYR A 1 516 ? 194.236 219.325 177.511 1.00 89.04  ? 548  TYR B N   1 
ATOM   3639  C CA  . TYR A 1 516 ? 195.634 219.319 177.940 1.00 89.04  ? 548  TYR B CA  1 
ATOM   3640  C C   . TYR A 1 516 ? 196.614 218.944 176.825 1.00 89.04  ? 548  TYR B C   1 
ATOM   3641  O O   . TYR A 1 516 ? 197.780 218.700 177.107 1.00 89.04  ? 548  TYR B O   1 
ATOM   3642  C CB  . TYR A 1 516 ? 195.819 218.472 179.202 1.00 119.52 ? 548  TYR B CB  1 
ATOM   3643  C CG  . TYR A 1 516 ? 195.104 219.098 180.370 1.00 119.52 ? 548  TYR B CG  1 
ATOM   3644  C CD1 . TYR A 1 516 ? 193.741 218.822 180.560 1.00 119.52 ? 548  TYR B CD1 1 
ATOM   3645  C CD2 . TYR A 1 516 ? 195.771 220.022 181.198 1.00 119.52 ? 548  TYR B CD2 1 
ATOM   3646  C CE1 . TYR A 1 516 ? 193.021 219.512 181.542 1.00 119.52 ? 548  TYR B CE1 1 
ATOM   3647  C CE2 . TYR A 1 516 ? 195.051 220.707 182.194 1.00 119.52 ? 548  TYR B CE2 1 
ATOM   3648  C CZ  . TYR A 1 516 ? 193.671 220.471 182.342 1.00 119.52 ? 548  TYR B CZ  1 
ATOM   3649  O OH  . TYR A 1 516 ? 192.950 221.183 183.237 1.00 119.52 ? 548  TYR B OH  1 
ATOM   3650  N N   . GLN A 1 517 ? 196.208 218.894 175.561 1.00 91.15  ? 549  GLN B N   1 
ATOM   3651  C CA  . GLN A 1 517 ? 197.143 218.571 174.497 1.00 91.15  ? 549  GLN B CA  1 
ATOM   3652  C C   . GLN A 1 517 ? 197.954 219.769 173.988 1.00 91.15  ? 549  GLN B C   1 
ATOM   3653  O O   . GLN A 1 517 ? 197.457 220.889 173.874 1.00 91.15  ? 549  GLN B O   1 
ATOM   3654  C CB  . GLN A 1 517 ? 196.441 217.818 173.381 1.00 123.89 ? 549  GLN B CB  1 
ATOM   3655  C CG  . GLN A 1 517 ? 195.781 216.520 173.837 1.00 123.89 ? 549  GLN B CG  1 
ATOM   3656  C CD  . GLN A 1 517 ? 195.896 215.450 172.765 1.00 123.89 ? 549  GLN B CD  1 
ATOM   3657  O OE1 . GLN A 1 517 ? 195.809 215.715 171.577 1.00 123.89 ? 549  GLN B OE1 1 
ATOM   3658  N NE2 . GLN A 1 517 ? 196.110 214.210 173.133 1.00 123.89 ? 549  GLN B NE2 1 
ATOM   3659  N N   . TYR A 1 518 ? 199.212 219.499 173.657 1.00 91.11  ? 550  TYR B N   1 
ATOM   3660  C CA  . TYR A 1 518 ? 200.174 220.406 173.044 1.00 91.11  ? 550  TYR B CA  1 
ATOM   3661  C C   . TYR A 1 518 ? 200.823 219.721 171.832 1.00 91.11  ? 550  TYR B C   1 
ATOM   3662  O O   . TYR A 1 518 ? 200.904 218.495 171.741 1.00 91.11  ? 550  TYR B O   1 
ATOM   3663  C CB  . TYR A 1 518 ? 201.228 220.835 174.059 1.00 122.30 ? 550  TYR B CB  1 
ATOM   3664  C CG  . TYR A 1 518 ? 202.228 219.735 174.307 1.00 122.30 ? 550  TYR B CG  1 
ATOM   3665  C CD1 . TYR A 1 518 ? 201.862 218.632 175.096 1.00 122.30 ? 550  TYR B CD1 1 
ATOM   3666  C CD2 . TYR A 1 518 ? 203.434 219.717 173.584 1.00 122.30 ? 550  TYR B CD2 1 
ATOM   3667  C CE1 . TYR A 1 518 ? 202.684 217.495 175.144 1.00 122.30 ? 550  TYR B CE1 1 
ATOM   3668  C CE2 . TYR A 1 518 ? 204.270 218.589 173.644 1.00 122.30 ? 550  TYR B CE2 1 
ATOM   3669  C CZ  . TYR A 1 518 ? 203.885 217.470 174.411 1.00 122.30 ? 550  TYR B CZ  1 
ATOM   3670  O OH  . TYR A 1 518 ? 204.658 216.355 174.433 1.00 122.30 ? 550  TYR B OH  1 
ATOM   3671  N N   . GLN A 1 519 ? 201.183 220.514 170.836 1.00 91.98  ? 551  GLN B N   1 
ATOM   3672  C CA  . GLN A 1 519 ? 201.577 220.064 169.515 1.00 91.98  ? 551  GLN B CA  1 
ATOM   3673  C C   . GLN A 1 519 ? 202.926 219.351 169.541 1.00 91.98  ? 551  GLN B C   1 
ATOM   3674  O O   . GLN A 1 519 ? 203.847 219.757 170.249 1.00 91.98  ? 551  GLN B O   1 
ATOM   3675  C CB  . GLN A 1 519 ? 201.570 221.254 168.553 1.00 125.02 ? 551  GLN B CB  1 
ATOM   3676  C CG  . GLN A 1 519 ? 201.746 220.799 167.100 1.00 125.02 ? 551  GLN B CG  1 
ATOM   3677  C CD  . GLN A 1 519 ? 201.587 221.924 166.091 1.00 125.02 ? 551  GLN B CD  1 
ATOM   3678  O OE1 . GLN A 1 519 ? 201.500 223.103 166.407 1.00 125.02 ? 551  GLN B OE1 1 
ATOM   3679  N NE2 . GLN A 1 519 ? 201.540 221.586 164.825 1.00 125.02 ? 551  GLN B NE2 1 
ATOM   3680  N N   . VAL A 1 520 ? 203.042 218.312 168.718 1.00 88.80  ? 552  VAL B N   1 
ATOM   3681  C CA  . VAL A 1 520 ? 204.263 217.509 168.560 1.00 88.80  ? 552  VAL B CA  1 
ATOM   3682  C C   . VAL A 1 520 ? 204.646 217.296 167.093 1.00 88.80  ? 552  VAL B C   1 
ATOM   3683  O O   . VAL A 1 520 ? 205.780 216.928 166.803 1.00 88.80  ? 552  VAL B O   1 
ATOM   3684  C CB  . VAL A 1 520 ? 204.123 216.158 169.279 1.00 125.05 ? 552  VAL B CB  1 
ATOM   3685  C CG1 . VAL A 1 520 ? 203.866 216.336 170.778 1.00 125.05 ? 552  VAL B CG1 1 
ATOM   3686  C CG2 . VAL A 1 520 ? 203.004 215.295 168.689 1.00 125.05 ? 552  VAL B CG2 1 
ATOM   3687  N N   . ASP A 1 521 ? 203.722 217.524 166.160 1.00 88.16  ? 553  ASP B N   1 
ATOM   3688  C CA  . ASP A 1 521 ? 203.953 217.482 164.718 1.00 88.16  ? 553  ASP B CA  1 
ATOM   3689  C C   . ASP A 1 521 ? 202.937 218.408 164.032 1.00 88.16  ? 553  ASP B C   1 
ATOM   3690  O O   . ASP A 1 521 ? 201.859 218.673 164.566 1.00 88.16  ? 553  ASP B O   1 
ATOM   3691  C CB  . ASP A 1 521 ? 203.937 216.005 164.252 1.00 112.26 ? 553  ASP B CB  1 
ATOM   3692  C CG  . ASP A 1 521 ? 204.258 215.751 162.774 1.00 112.26 ? 553  ASP B CG  1 
ATOM   3693  O OD1 . ASP A 1 521 ? 204.531 216.714 162.029 1.00 112.26 ? 553  ASP B OD1 1 
ATOM   3694  O OD2 . ASP A 1 521 ? 204.207 214.578 162.354 1.00 112.26 ? 553  ASP B OD2 1 
ATOM   3695  N N   . ARG A 1 522 ? 203.244 218.898 162.833 1.00 87.62  ? 554  ARG B N   1 
ATOM   3696  C CA  . ARG A 1 522 ? 202.311 219.636 161.973 1.00 87.62  ? 554  ARG B CA  1 
ATOM   3697  C C   . ARG A 1 522 ? 200.942 218.968 161.882 1.00 87.62  ? 554  ARG B C   1 
ATOM   3698  O O   . ARG A 1 522 ? 199.948 219.686 161.858 1.00 87.62  ? 554  ARG B O   1 
ATOM   3699  C CB  . ARG A 1 522 ? 202.937 219.759 160.578 1.00 123.06 ? 554  ARG B CB  1 
ATOM   3700  C CG  . ARG A 1 522 ? 202.105 220.562 159.564 1.00 123.06 ? 554  ARG B CG  1 
ATOM   3701  C CD  . ARG A 1 522 ? 202.016 222.062 159.874 1.00 123.06 ? 554  ARG B CD  1 
ATOM   3702  N NE  . ARG A 1 522 ? 201.005 222.401 160.900 1.00 123.06 ? 554  ARG B NE  1 
ATOM   3703  C CZ  . ARG A 1 522 ? 200.823 223.599 161.433 1.00 123.06 ? 554  ARG B CZ  1 
ATOM   3704  N NH1 . ARG A 1 522 ? 199.868 223.811 162.284 1.00 123.06 ? 554  ARG B NH1 1 
ATOM   3705  N NH2 . ARG A 1 522 ? 201.558 224.617 161.116 1.00 123.06 ? 554  ARG B NH2 1 
ATOM   3706  N N   . TYR A 1 523 ? 200.892 217.643 161.864 1.00 90.14  ? 555  TYR B N   1 
ATOM   3707  C CA  . TYR A 1 523 ? 199.671 216.841 161.869 1.00 90.14  ? 555  TYR B CA  1 
ATOM   3708  C C   . TYR A 1 523 ? 199.243 216.330 163.249 1.00 90.14  ? 555  TYR B C   1 
ATOM   3709  O O   . TYR A 1 523 ? 198.170 215.734 163.351 1.00 90.14  ? 555  TYR B O   1 
ATOM   3710  C CB  . TYR A 1 523 ? 199.824 215.676 160.883 1.00 120.99 ? 555  TYR B CB  1 
ATOM   3711  C CG  . TYR A 1 523 ? 199.579 216.093 159.456 1.00 120.99 ? 555  TYR B CG  1 
ATOM   3712  C CD1 . TYR A 1 523 ? 200.569 216.797 158.746 1.00 120.99 ? 555  TYR B CD1 1 
ATOM   3713  C CD2 . TYR A 1 523 ? 198.339 215.813 158.851 1.00 120.99 ? 555  TYR B CD2 1 
ATOM   3714  C CE1 . TYR A 1 523 ? 200.313 217.229 157.430 1.00 120.99 ? 555  TYR B CE1 1 
ATOM   3715  C CE2 . TYR A 1 523 ? 198.071 216.277 157.554 1.00 120.99 ? 555  TYR B CE2 1 
ATOM   3716  C CZ  . TYR A 1 523 ? 199.056 216.982 156.840 1.00 120.99 ? 555  TYR B CZ  1 
ATOM   3717  O OH  . TYR A 1 523 ? 198.775 217.416 155.585 1.00 120.99 ? 555  TYR B OH  1 
ATOM   3718  N N   . THR A 1 524 ? 200.006 216.533 164.327 1.00 91.13  ? 556  THR B N   1 
ATOM   3719  C CA  . THR A 1 524 ? 199.772 215.806 165.586 1.00 91.13  ? 556  THR B CA  1 
ATOM   3720  C C   . THR A 1 524 ? 199.950 216.654 166.834 1.00 91.13  ? 556  THR B C   1 
ATOM   3721  O O   . THR A 1 524 ? 200.866 217.462 166.960 1.00 91.13  ? 556  THR B O   1 
ATOM   3722  C CB  . THR A 1 524 ? 200.611 214.521 165.674 1.00 124.75 ? 556  THR B CB  1 
ATOM   3723  O OG1 . THR A 1 524 ? 200.437 213.748 164.516 1.00 124.75 ? 556  THR B OG1 1 
ATOM   3724  C CG2 . THR A 1 524 ? 200.223 213.623 166.847 1.00 124.75 ? 556  THR B CG2 1 
ATOM   3725  N N   . CYS A 1 525 ? 199.093 216.405 167.815 1.00 92.59  ? 557  CYS B N   1 
ATOM   3726  C CA  . CYS A 1 525 ? 199.129 216.994 169.144 1.00 92.59  ? 557  CYS B CA  1 
ATOM   3727  C C   . CYS A 1 525 ? 198.955 215.886 170.187 1.00 92.59  ? 557  CYS B C   1 
ATOM   3728  O O   . CYS A 1 525 ? 198.339 214.865 169.882 1.00 92.59  ? 557  CYS B O   1 
ATOM   3729  C CB  . CYS A 1 525 ? 198.025 218.046 169.200 1.00 119.98 ? 557  CYS B CB  1 
ATOM   3730  S SG  . CYS A 1 525 ? 198.203 219.263 170.494 1.00 119.98 ? 557  CYS B SG  1 
ATOM   3731  N N   . LYS A 1 526 ? 199.529 216.036 171.383 1.00 91.57  ? 558  LYS B N   1 
ATOM   3732  C CA  . LYS A 1 526 ? 199.547 214.987 172.414 1.00 91.57  ? 558  LYS B CA  1 
ATOM   3733  C C   . LYS A 1 526 ? 199.364 215.573 173.794 1.00 91.57  ? 558  LYS B C   1 
ATOM   3734  O O   . LYS A 1 526 ? 199.626 216.748 174.013 1.00 91.57  ? 558  LYS B O   1 
ATOM   3735  C CB  . LYS A 1 526 ? 200.853 214.187 172.348 1.00 130.98 ? 558  LYS B CB  1 
ATOM   3736  C CG  . LYS A 1 526 ? 200.895 213.316 171.088 1.00 130.98 ? 558  LYS B CG  1 
ATOM   3737  C CD  . LYS A 1 526 ? 202.115 212.395 171.098 1.00 130.98 ? 558  LYS B CD  1 
ATOM   3738  C CE  . LYS A 1 526 ? 202.138 211.573 169.807 1.00 130.98 ? 558  LYS B CE  1 
ATOM   3739  N NZ  . LYS A 1 526 ? 203.338 210.706 169.744 1.00 130.98 ? 558  LYS B NZ  1 
ATOM   3740  N N   . THR A 1 527 ? 198.871 214.777 174.729 1.00 90.27  ? 559  THR B N   1 
ATOM   3741  C CA  . THR A 1 527 ? 198.522 215.276 176.056 1.00 90.27  ? 559  THR B CA  1 
ATOM   3742  C C   . THR A 1 527 ? 199.768 215.608 176.858 1.00 90.27  ? 559  THR B C   1 
ATOM   3743  O O   . THR A 1 527 ? 200.671 214.788 177.010 1.00 90.27  ? 559  THR B O   1 
ATOM   3744  C CB  . THR A 1 527 ? 197.612 214.313 176.819 1.00 123.57 ? 559  THR B CB  1 
ATOM   3745  O OG1 . THR A 1 527 ? 196.633 213.782 175.953 1.00 123.57 ? 559  THR B OG1 1 
ATOM   3746  C CG2 . THR A 1 527 ? 196.842 215.058 177.904 1.00 123.57 ? 559  THR B CG2 1 
ATOM   3747  N N   . CYS A 1 528 ? 199.800 216.820 177.388 1.00 89.88  ? 560  CYS B N   1 
ATOM   3748  C CA  . CYS A 1 528 ? 200.791 217.255 178.346 1.00 89.88  ? 560  CYS B CA  1 
ATOM   3749  C C   . CYS A 1 528 ? 200.661 216.462 179.659 1.00 89.88  ? 560  CYS B C   1 
ATOM   3750  O O   . CYS A 1 528 ? 199.535 216.203 180.100 1.00 89.88  ? 560  CYS B O   1 
ATOM   3751  C CB  . CYS A 1 528 ? 200.568 218.743 178.577 1.00 116.47 ? 560  CYS B CB  1 
ATOM   3752  S SG  . CYS A 1 528 ? 201.690 219.450 179.768 1.00 116.47 ? 560  CYS B SG  1 
ATOM   3753  N N   . PRO A 1 529 ? 201.775 216.068 180.301 1.00 89.47  ? 561  PRO B N   1 
ATOM   3754  C CA  . PRO A 1 529 ? 201.739 215.388 181.588 1.00 89.47  ? 561  PRO B CA  1 
ATOM   3755  C C   . PRO A 1 529 ? 201.079 216.222 182.686 1.00 89.47  ? 561  PRO B C   1 
ATOM   3756  O O   . PRO A 1 529 ? 200.596 217.338 182.497 1.00 89.47  ? 561  PRO B O   1 
ATOM   3757  C CB  . PRO A 1 529 ? 203.187 215.031 181.943 1.00 152.88 ? 561  PRO B CB  1 
ATOM   3758  C CG  . PRO A 1 529 ? 203.950 215.197 180.639 1.00 152.88 ? 561  PRO B CG  1 
ATOM   3759  C CD  . PRO A 1 529 ? 203.148 216.232 179.859 1.00 152.88 ? 561  PRO B CD  1 
ATOM   3760  N N   . TYR A 1 530 ? 201.013 215.633 183.869 1.00 84.24  ? 562  TYR B N   1 
ATOM   3761  C CA  . TYR A 1 530 ? 200.347 216.250 185.002 1.00 84.24  ? 562  TYR B CA  1 
ATOM   3762  C C   . TYR A 1 530 ? 201.056 217.493 185.529 1.00 84.24  ? 562  TYR B C   1 
ATOM   3763  O O   . TYR A 1 530 ? 200.397 218.370 186.067 1.00 84.24  ? 562  TYR B O   1 
ATOM   3764  C CB  . TYR A 1 530 ? 200.134 215.179 186.052 1.00 113.07 ? 562  TYR B CB  1 
ATOM   3765  C CG  . TYR A 1 530 ? 198.927 214.375 185.650 1.00 113.07 ? 562  TYR B CG  1 
ATOM   3766  C CD1 . TYR A 1 530 ? 197.644 214.868 185.949 1.00 113.07 ? 562  TYR B CD1 1 
ATOM   3767  C CD2 . TYR A 1 530 ? 199.083 213.248 184.829 1.00 113.07 ? 562  TYR B CD2 1 
ATOM   3768  C CE1 . TYR A 1 530 ? 196.507 214.215 185.446 1.00 113.07 ? 562  TYR B CE1 1 
ATOM   3769  C CE2 . TYR A 1 530 ? 197.947 212.607 184.310 1.00 113.07 ? 562  TYR B CE2 1 
ATOM   3770  C CZ  . TYR A 1 530 ? 196.660 213.088 184.619 1.00 113.07 ? 562  TYR B CZ  1 
ATOM   3771  O OH  . TYR A 1 530 ? 195.567 212.473 184.104 1.00 113.07 ? 562  TYR B OH  1 
ATOM   3772  N N   . ASP A 1 531 ? 202.359 217.622 185.301 1.00 82.55  ? 563  ASP B N   1 
ATOM   3773  C CA  . ASP A 1 531 ? 203.152 218.798 185.672 1.00 82.55  ? 563  ASP B CA  1 
ATOM   3774  C C   . ASP A 1 531 ? 202.611 220.129 185.126 1.00 82.55  ? 563  ASP B C   1 
ATOM   3775  O O   . ASP A 1 531 ? 202.816 221.189 185.729 1.00 82.55  ? 563  ASP B O   1 
ATOM   3776  C CB  . ASP A 1 531 ? 204.599 218.602 185.180 1.00 105.12 ? 563  ASP B CB  1 
ATOM   3777  C CG  . ASP A 1 531 ? 204.789 218.330 183.675 1.00 105.12 ? 563  ASP B CG  1 
ATOM   3778  O OD1 . ASP A 1 531 ? 203.799 218.207 182.927 1.00 105.12 ? 563  ASP B OD1 1 
ATOM   3779  O OD2 . ASP A 1 531 ? 205.965 218.230 183.261 1.00 105.12 ? 563  ASP B OD2 1 
ATOM   3780  N N   . MET A 1 532 ? 201.958 220.098 183.969 1.00 89.19  ? 564  MET B N   1 
ATOM   3781  C CA  . MET A 1 532 ? 201.738 221.291 183.174 1.00 89.19  ? 564  MET B CA  1 
ATOM   3782  C C   . MET A 1 532 ? 200.392 221.296 182.439 1.00 89.19  ? 564  MET B C   1 
ATOM   3783  O O   . MET A 1 532 ? 199.774 220.271 182.166 1.00 89.19  ? 564  MET B O   1 
ATOM   3784  C CB  . MET A 1 532 ? 202.931 221.457 182.233 1.00 124.08 ? 564  MET B CB  1 
ATOM   3785  C CG  . MET A 1 532 ? 204.241 221.795 182.923 1.00 124.08 ? 564  MET B CG  1 
ATOM   3786  S SD  . MET A 1 532 ? 205.430 222.549 181.810 1.00 124.08 ? 564  MET B SD  1 
ATOM   3787  C CE  . MET A 1 532 ? 205.923 221.080 180.878 1.00 124.08 ? 564  MET B CE  1 
ATOM   3788  N N   . ARG A 1 533 ? 199.929 222.503 182.125 1.00 88.25  ? 565  ARG B N   1 
ATOM   3789  C CA  . ARG A 1 533 ? 198.782 222.853 181.285 1.00 88.25  ? 565  ARG B CA  1 
ATOM   3790  C C   . ARG A 1 533 ? 199.310 223.481 179.989 1.00 88.25  ? 565  ARG B C   1 
ATOM   3791  O O   . ARG A 1 533 ? 200.306 224.195 180.049 1.00 88.25  ? 565  ARG B O   1 
ATOM   3792  C CB  . ARG A 1 533 ? 197.814 223.765 182.061 1.00 123.94 ? 565  ARG B CB  1 
ATOM   3793  C CG  . ARG A 1 533 ? 197.054 223.151 183.249 1.00 123.94 ? 565  ARG B CG  1 
ATOM   3794  C CD  . ARG A 1 533 ? 196.263 224.179 184.039 1.00 123.94 ? 565  ARG B CD  1 
ATOM   3795  N NE  . ARG A 1 533 ? 197.166 225.149 184.655 1.00 123.94 ? 565  ARG B NE  1 
ATOM   3796  C CZ  . ARG A 1 533 ? 196.834 226.174 185.407 1.00 123.94 ? 565  ARG B CZ  1 
ATOM   3797  N NH1 . ARG A 1 533 ? 197.757 226.932 185.897 1.00 123.94 ? 565  ARG B NH1 1 
ATOM   3798  N NH2 . ARG A 1 533 ? 195.601 226.485 185.678 1.00 123.94 ? 565  ARG B NH2 1 
ATOM   3799  N N   . PRO A 1 534 ? 198.774 223.179 178.798 1.00 90.41  ? 566  PRO B N   1 
ATOM   3800  C CA  . PRO A 1 534 ? 199.367 223.643 177.541 1.00 90.41  ? 566  PRO B CA  1 
ATOM   3801  C C   . PRO A 1 534 ? 199.646 225.148 177.468 1.00 90.41  ? 566  PRO B C   1 
ATOM   3802  O O   . PRO A 1 534 ? 198.916 225.965 178.032 1.00 90.41  ? 566  PRO B O   1 
ATOM   3803  C CB  . PRO A 1 534 ? 198.395 223.223 176.444 1.00 154.49 ? 566  PRO B CB  1 
ATOM   3804  C CG  . PRO A 1 534 ? 197.847 221.928 177.020 1.00 154.49 ? 566  PRO B CG  1 
ATOM   3805  C CD  . PRO A 1 534 ? 197.737 222.204 178.518 1.00 154.49 ? 566  PRO B CD  1 
ATOM   3806  N N   . THR A 1 535 ? 200.656 225.521 176.682 1.00 89.16  ? 567  THR B N   1 
ATOM   3807  C CA  . THR A 1 535 ? 200.738 226.871 176.108 1.00 89.16  ? 567  THR B CA  1 
ATOM   3808  C C   . THR A 1 535 ? 199.452 227.138 175.319 1.00 89.16  ? 567  THR B C   1 
ATOM   3809  O O   . THR A 1 535 ? 198.992 226.234 174.625 1.00 89.16  ? 567  THR B O   1 
ATOM   3810  C CB  . THR A 1 535 ? 201.920 226.969 175.128 1.00 122.05 ? 567  THR B CB  1 
ATOM   3811  O OG1 . THR A 1 535 ? 201.750 225.971 174.161 1.00 122.05 ? 567  THR B OG1 1 
ATOM   3812  C CG2 . THR A 1 535 ? 203.303 226.735 175.729 1.00 122.05 ? 567  THR B CG2 1 
ATOM   3813  N N   . GLU A 1 536 ? 198.901 228.346 175.321 1.00 85.24  ? 568  GLU B N   1 
ATOM   3814  C CA  . GLU A 1 536 ? 197.736 228.677 174.476 1.00 85.24  ? 568  GLU B CA  1 
ATOM   3815  C C   . GLU A 1 536 ? 198.008 228.462 172.980 1.00 85.24  ? 568  GLU B C   1 
ATOM   3816  O O   . GLU A 1 536 ? 197.169 227.926 172.265 1.00 85.24  ? 568  GLU B O   1 
ATOM   3817  C CB  . GLU A 1 536 ? 197.247 230.113 174.744 1.00 112.34 ? 568  GLU B CB  1 
ATOM   3818  C CG  . GLU A 1 536 ? 198.150 231.252 174.243 1.00 112.34 ? 568  GLU B CG  1 
ATOM   3819  C CD  . GLU A 1 536 ? 199.333 231.493 175.180 1.00 112.34 ? 568  GLU B CD  1 
ATOM   3820  O OE1 . GLU A 1 536 ? 199.534 230.744 176.164 1.00 112.34 ? 568  GLU B OE1 1 
ATOM   3821  O OE2 . GLU A 1 536 ? 199.994 232.541 175.027 1.00 112.34 ? 568  GLU B OE2 1 
ATOM   3822  N N   . ASN A 1 537 ? 199.225 228.767 172.520 1.00 87.91  ? 569  ASN B N   1 
ATOM   3823  C CA  . ASN A 1 537 ? 199.692 228.479 171.162 1.00 87.91  ? 569  ASN B CA  1 
ATOM   3824  C C   . ASN A 1 537 ? 199.842 226.975 170.899 1.00 87.91  ? 569  ASN B C   1 
ATOM   3825  O O   . ASN A 1 537 ? 200.142 226.554 169.786 1.00 87.91  ? 569  ASN B O   1 
ATOM   3826  C CB  . ASN A 1 537 ? 201.049 229.172 170.955 1.00 116.94 ? 569  ASN B CB  1 
ATOM   3827  C CG  . ASN A 1 537 ? 200.998 230.683 171.034 1.00 116.94 ? 569  ASN B CG  1 
ATOM   3828  O OD1 . ASN A 1 537 ? 199.954 231.310 170.960 1.00 116.94 ? 569  ASN B OD1 1 
ATOM   3829  N ND2 . ASN A 1 537 ? 202.132 231.319 171.143 1.00 116.94 ? 569  ASN B ND2 1 
ATOM   3830  N N   . ARG A 1 538 ? 199.729 226.169 171.958 1.00 88.77  ? 570  ARG B N   1 
ATOM   3831  C CA  . ARG A 1 538 ? 199.980 224.722 172.024 1.00 88.77  ? 570  ARG B CA  1 
ATOM   3832  C C   . ARG A 1 538 ? 201.347 224.312 171.484 1.00 88.77  ? 570  ARG B C   1 
ATOM   3833  O O   . ARG A 1 538 ? 201.577 223.144 171.241 1.00 88.77  ? 570  ARG B O   1 
ATOM   3834  C CB  . ARG A 1 538 ? 198.774 223.973 171.445 1.00 124.67 ? 570  ARG B CB  1 
ATOM   3835  C CG  . ARG A 1 538 ? 197.551 224.249 172.334 1.00 124.67 ? 570  ARG B CG  1 
ATOM   3836  C CD  . ARG A 1 538 ? 196.297 223.578 171.796 1.00 124.67 ? 570  ARG B CD  1 
ATOM   3837  N NE  . ARG A 1 538 ? 195.116 224.020 172.544 1.00 124.67 ? 570  ARG B NE  1 
ATOM   3838  C CZ  . ARG A 1 538 ? 194.683 223.566 173.698 1.00 124.67 ? 570  ARG B CZ  1 
ATOM   3839  N NH1 . ARG A 1 538 ? 193.633 224.088 174.250 1.00 124.67 ? 570  ARG B NH1 1 
ATOM   3840  N NH2 . ARG A 1 538 ? 195.277 222.596 174.328 1.00 124.67 ? 570  ARG B NH2 1 
ATOM   3841  N N   . THR A 1 539 ? 202.287 225.239 171.386 1.00 90.19  ? 571  THR B N   1 
ATOM   3842  C CA  . THR A 1 539 ? 203.696 224.987 171.072 1.00 90.19  ? 571  THR B CA  1 
ATOM   3843  C C   . THR A 1 539 ? 204.366 224.069 172.092 1.00 90.19  ? 571  THR B C   1 
ATOM   3844  O O   . THR A 1 539 ? 205.304 223.351 171.761 1.00 90.19  ? 571  THR B O   1 
ATOM   3845  C CB  . THR A 1 539 ? 204.448 226.323 171.050 1.00 123.46 ? 571  THR B CB  1 
ATOM   3846  O OG1 . THR A 1 539 ? 204.146 227.083 172.202 1.00 123.46 ? 571  THR B OG1 1 
ATOM   3847  C CG2 . THR A 1 539 ? 204.059 227.165 169.840 1.00 123.46 ? 571  THR B CG2 1 
ATOM   3848  N N   . GLY A 1 540 ? 203.878 224.063 173.327 1.00 89.51  ? 572  GLY B N   1 
ATOM   3849  C CA  . GLY A 1 540 ? 204.401 223.259 174.416 1.00 89.51  ? 572  GLY B CA  1 
ATOM   3850  C C   . GLY A 1 540 ? 203.454 223.286 175.600 1.00 89.51  ? 572  GLY B C   1 
ATOM   3851  O O   . GLY A 1 540 ? 202.234 223.398 175.452 1.00 89.51  ? 572  GLY B O   1 
ATOM   3852  N N   . CYS A 1 541 ? 204.008 223.242 176.802 1.00 91.34  ? 573  CYS B N   1 
ATOM   3853  C CA  . CYS A 1 541 ? 203.227 223.200 178.029 1.00 91.34  ? 573  CYS B CA  1 
ATOM   3854  C C   . CYS A 1 541 ? 203.865 224.044 179.142 1.00 91.34  ? 573  CYS B C   1 
ATOM   3855  O O   . CYS A 1 541 ? 205.053 224.364 179.078 1.00 91.34  ? 573  CYS B O   1 
ATOM   3856  C CB  . CYS A 1 541 ? 203.019 221.727 178.374 1.00 118.36 ? 573  CYS B CB  1 
ATOM   3857  S SG  . CYS A 1 541 ? 201.541 221.406 179.332 1.00 118.36 ? 573  CYS B SG  1 
ATOM   3858  N N   . ARG A 1 542 ? 203.059 224.466 180.120 1.00 89.98  ? 574  ARG B N   1 
ATOM   3859  C CA  . ARG A 1 542 ? 203.412 225.423 181.180 1.00 89.98  ? 574  ARG B CA  1 
ATOM   3860  C C   . ARG A 1 542 ? 202.945 224.920 182.544 1.00 89.98  ? 574  ARG B C   1 
ATOM   3861  O O   . ARG A 1 542 ? 201.861 224.354 182.606 1.00 89.98  ? 574  ARG B O   1 
ATOM   3862  C CB  . ARG A 1 542 ? 202.763 226.783 180.899 1.00 30.00  ? 574  ARG B CB  1 
ATOM   3863  C CG  . ARG A 1 542 ? 203.226 227.396 179.579 1.00 30.00  ? 574  ARG B CG  1 
ATOM   3864  C CD  . ARG A 1 542 ? 202.587 228.761 179.378 1.00 30.00  ? 574  ARG B CD  1 
ATOM   3865  N NE  . ARG A 1 542 ? 202.952 229.330 178.068 1.00 30.00  ? 574  ARG B NE  1 
ATOM   3866  C CZ  . ARG A 1 542 ? 202.149 229.926 177.210 1.00 30.00  ? 574  ARG B CZ  1 
ATOM   3867  N NH1 . ARG A 1 542 ? 202.556 230.251 176.020 1.00 30.00  ? 574  ARG B NH1 1 
ATOM   3868  N NH2 . ARG A 1 542 ? 200.911 230.180 177.501 1.00 30.00  ? 574  ARG B NH2 1 
ATOM   3869  N N   . PRO A 1 543 ? 203.682 225.147 183.637 1.00 87.87  ? 575  PRO B N   1 
ATOM   3870  C CA  . PRO A 1 543 ? 203.314 224.723 184.987 1.00 87.87  ? 575  PRO B CA  1 
ATOM   3871  C C   . PRO A 1 543 ? 201.835 224.853 185.304 1.00 87.87  ? 575  PRO B C   1 
ATOM   3872  O O   . PRO A 1 543 ? 201.228 225.905 185.106 1.00 87.87  ? 575  PRO B O   1 
ATOM   3873  C CB  . PRO A 1 543 ? 204.161 225.586 185.913 1.00 150.15 ? 575  PRO B CB  1 
ATOM   3874  C CG  . PRO A 1 543 ? 205.446 225.728 185.109 1.00 150.15 ? 575  PRO B CG  1 
ATOM   3875  C CD  . PRO A 1 543 ? 204.954 225.844 183.671 1.00 150.15 ? 575  PRO B CD  1 
ATOM   3876  N N   . ILE A 1 544 ? 201.261 223.783 185.839 1.00 87.57  ? 576  ILE B N   1 
ATOM   3877  C CA  . ILE A 1 544 ? 200.043 223.902 186.628 1.00 87.57  ? 576  ILE B CA  1 
ATOM   3878  C C   . ILE A 1 544 ? 200.397 224.775 187.841 1.00 87.57  ? 576  ILE B C   1 
ATOM   3879  O O   . ILE A 1 544 ? 201.329 224.426 188.567 1.00 87.57  ? 576  ILE B O   1 
ATOM   3880  C CB  . ILE A 1 544 ? 199.567 222.512 187.087 1.00 124.47 ? 576  ILE B CB  1 
ATOM   3881  C CG1 . ILE A 1 544 ? 199.310 221.531 185.929 1.00 124.47 ? 576  ILE B CG1 1 
ATOM   3882  C CG2 . ILE A 1 544 ? 198.310 222.641 187.949 1.00 124.47 ? 576  ILE B CG2 1 
ATOM   3883  C CD1 . ILE A 1 544 ? 198.076 221.807 185.077 1.00 124.47 ? 576  ILE B CD1 1 
ATOM   3884  N N   . PRO A 1 545 ? 199.721 225.904 188.093 1.00 85.26  ? 577  PRO B N   1 
ATOM   3885  C CA  . PRO A 1 545 ? 199.907 226.648 189.332 1.00 85.26  ? 577  PRO B CA  1 
ATOM   3886  C C   . PRO A 1 545 ? 199.517 225.772 190.517 1.00 85.26  ? 577  PRO B C   1 
ATOM   3887  O O   . PRO A 1 545 ? 198.452 225.143 190.486 1.00 85.26  ? 577  PRO B O   1 
ATOM   3888  C CB  . PRO A 1 545 ? 199.011 227.882 189.231 1.00 145.69 ? 577  PRO B CB  1 
ATOM   3889  C CG  . PRO A 1 545 ? 198.777 228.013 187.728 1.00 145.69 ? 577  PRO B CG  1 
ATOM   3890  C CD  . PRO A 1 545 ? 198.753 226.567 187.250 1.00 145.69 ? 577  PRO B CD  1 
ATOM   3891  N N   . ILE A 1 546 ? 200.364 225.715 191.547 1.00 84.46  ? 578  ILE B N   1 
ATOM   3892  C CA  . ILE A 1 546 ? 200.058 224.884 192.696 1.00 84.46  ? 578  ILE B CA  1 
ATOM   3893  C C   . ILE A 1 546 ? 199.551 225.668 193.878 1.00 84.46  ? 578  ILE B C   1 
ATOM   3894  O O   . ILE A 1 546 ? 200.153 226.654 194.301 1.00 84.46  ? 578  ILE B O   1 
ATOM   3895  C CB  . ILE A 1 546 ? 201.290 224.049 193.085 1.00 120.05 ? 578  ILE B CB  1 
ATOM   3896  C CG1 . ILE A 1 546 ? 201.794 223.258 191.838 1.00 120.05 ? 578  ILE B CG1 1 
ATOM   3897  C CG2 . ILE A 1 546 ? 200.984 223.107 194.245 1.00 120.05 ? 578  ILE B CG2 1 
ATOM   3898  C CD1 . ILE A 1 546 ? 200.784 222.313 191.185 1.00 120.05 ? 578  ILE B CD1 1 
ATOM   3899  N N   . ILE A 1 547 ? 198.439 225.199 194.389 1.00 82.48  ? 579  ILE B N   1 
ATOM   3900  C CA  . ILE A 1 547 ? 197.733 225.723 195.523 1.00 82.48  ? 579  ILE B CA  1 
ATOM   3901  C C   . ILE A 1 547 ? 198.325 225.196 196.802 1.00 82.48  ? 579  ILE B C   1 
ATOM   3902  O O   . ILE A 1 547 ? 198.686 224.030 196.887 1.00 82.48  ? 579  ILE B O   1 
ATOM   3903  C CB  . ILE A 1 547 ? 196.235 225.370 195.443 1.00 30.00  ? 579  ILE B CB  1 
ATOM   3904  C CG1 . ILE A 1 547 ? 195.581 226.088 194.261 1.00 30.00  ? 579  ILE B CG1 1 
ATOM   3905  C CG2 . ILE A 1 547 ? 195.534 225.727 196.744 1.00 30.00  ? 579  ILE B CG2 1 
ATOM   3906  C CD1 . ILE A 1 547 ? 194.184 225.600 193.949 1.00 30.00  ? 579  ILE B CD1 1 
ATOM   3907  N N   . LYS A 1 548 ? 198.503 226.063 197.771 1.00 82.64  ? 580  LYS B N   1 
ATOM   3908  C CA  . LYS A 1 548 ? 199.009 225.642 199.059 1.00 82.64  ? 580  LYS B CA  1 
ATOM   3909  C C   . LYS A 1 548 ? 197.928 225.931 200.060 1.00 82.64  ? 580  LYS B C   1 
ATOM   3910  O O   . LYS A 1 548 ? 197.115 226.830 199.844 1.00 82.64  ? 580  LYS B O   1 
ATOM   3911  C CB  . LYS A 1 548 ? 200.288 226.398 199.416 1.00 118.21 ? 580  LYS B CB  1 
ATOM   3912  C CG  . LYS A 1 548 ? 201.456 226.100 198.492 1.00 118.21 ? 580  LYS B CG  1 
ATOM   3913  C CD  . LYS A 1 548 ? 202.650 227.026 198.728 1.00 118.21 ? 580  LYS B CD  1 
ATOM   3914  C CE  . LYS A 1 548 ? 203.359 226.781 200.074 1.00 118.21 ? 580  LYS B CE  1 
ATOM   3915  N NZ  . LYS A 1 548 ? 204.637 227.543 200.158 1.00 118.21 ? 580  LYS B NZ  1 
ATOM   3916  N N   . LEU A 1 549 ? 197.906 225.218 201.167 1.00 82.44  ? 581  LEU B N   1 
ATOM   3917  C CA  . LEU A 1 549 ? 196.948 225.604 202.168 1.00 82.44  ? 581  LEU B CA  1 
ATOM   3918  C C   . LEU A 1 549 ? 197.527 226.786 202.878 1.00 82.44  ? 581  LEU B C   1 
ATOM   3919  O O   . LEU A 1 549 ? 198.637 226.723 203.405 1.00 82.44  ? 581  LEU B O   1 
ATOM   3920  C CB  . LEU A 1 549 ? 196.664 224.465 203.146 1.00 117.18 ? 581  LEU B CB  1 
ATOM   3921  C CG  . LEU A 1 549 ? 195.701 224.786 204.332 1.00 117.18 ? 581  LEU B CG  1 
ATOM   3922  C CD1 . LEU A 1 549 ? 194.293 225.157 203.848 1.00 117.18 ? 581  LEU B CD1 1 
ATOM   3923  C CD2 . LEU A 1 549 ? 195.616 223.553 205.209 1.00 117.18 ? 581  LEU B CD2 1 
ATOM   3924  N N   . GLU A 1 550 ? 196.788 227.872 202.850 1.00 86.29  ? 582  GLU B N   1 
ATOM   3925  C CA  . GLU A 1 550 ? 197.229 229.089 203.461 1.00 86.29  ? 582  GLU B CA  1 
ATOM   3926  C C   . GLU A 1 550 ? 196.615 229.182 204.826 1.00 86.29  ? 582  GLU B C   1 
ATOM   3927  O O   . GLU A 1 550 ? 195.399 229.177 204.973 1.00 86.29  ? 582  GLU B O   1 
ATOM   3928  C CB  . GLU A 1 550 ? 196.847 230.282 202.596 1.00 113.72 ? 582  GLU B CB  1 
ATOM   3929  C CG  . GLU A 1 550 ? 197.344 231.606 203.091 1.00 113.72 ? 582  GLU B CG  1 
ATOM   3930  C CD  . GLU A 1 550 ? 196.948 232.729 202.206 1.00 113.72 ? 582  GLU B CD  1 
ATOM   3931  O OE1 . GLU A 1 550 ? 196.144 232.514 201.335 1.00 113.72 ? 582  GLU B OE1 1 
ATOM   3932  O OE2 . GLU A 1 550 ? 197.470 233.802 202.373 1.00 113.72 ? 582  GLU B OE2 1 
ATOM   3933  N N   . TRP A 1 551 ? 197.457 229.334 205.814 1.00 88.31  ? 583  TRP B N   1 
ATOM   3934  C CA  . TRP A 1 551 ? 197.064 229.413 207.207 1.00 88.31  ? 583  TRP B CA  1 
ATOM   3935  C C   . TRP A 1 551 ? 196.345 230.713 207.509 1.00 88.31  ? 583  TRP B C   1 
ATOM   3936  O O   . TRP A 1 551 ? 195.608 230.830 208.482 1.00 88.31  ? 583  TRP B O   1 
ATOM   3937  C CB  . TRP A 1 551 ? 198.317 229.247 208.038 1.00 118.23 ? 583  TRP B CB  1 
ATOM   3938  C CG  . TRP A 1 551 ? 199.378 230.158 207.587 1.00 118.23 ? 583  TRP B CG  1 
ATOM   3939  C CD1 . TRP A 1 551 ? 199.607 231.424 207.978 1.00 118.23 ? 583  TRP B CD1 1 
ATOM   3940  C CD2 . TRP A 1 551 ? 200.375 229.862 206.579 1.00 118.23 ? 583  TRP B CD2 1 
ATOM   3941  N NE1 . TRP A 1 551 ? 200.668 231.943 207.289 1.00 118.23 ? 583  TRP B NE1 1 
ATOM   3942  C CE2 . TRP A 1 551 ? 201.145 231.000 206.428 1.00 118.23 ? 583  TRP B CE2 1 
ATOM   3943  C CE3 . TRP A 1 551 ? 200.658 228.726 205.795 1.00 118.23 ? 583  TRP B CE3 1 
ATOM   3944  C CZ2 . TRP A 1 551 ? 202.188 231.061 205.528 1.00 118.23 ? 583  TRP B CZ2 1 
ATOM   3945  C CZ3 . TRP A 1 551 ? 201.691 228.789 204.894 1.00 118.23 ? 583  TRP B CZ3 1 
ATOM   3946  C CH2 . TRP A 1 551 ? 202.443 229.923 204.761 1.00 118.23 ? 583  TRP B CH2 1 
ATOM   3947  N N   . GLY A 1 552 ? 196.508 231.654 206.604 1.00 86.05  ? 584  GLY B N   1 
ATOM   3948  C CA  . GLY A 1 552 ? 195.888 232.952 206.656 1.00 86.05  ? 584  GLY B CA  1 
ATOM   3949  C C   . GLY A 1 552 ? 194.672 233.047 205.742 1.00 86.05  ? 584  GLY B C   1 
ATOM   3950  O O   . GLY A 1 552 ? 194.166 234.149 205.508 1.00 86.05  ? 584  GLY B O   1 
ATOM   3951  N N   . SER A 1 553 ? 194.183 231.923 205.213 1.00 87.66  ? 585  SER B N   1 
ATOM   3952  C CA  . SER A 1 553 ? 193.035 232.017 204.328 1.00 87.66  ? 585  SER B CA  1 
ATOM   3953  C C   . SER A 1 553 ? 191.874 232.457 205.208 1.00 87.66  ? 585  SER B C   1 
ATOM   3954  O O   . SER A 1 553 ? 191.911 232.206 206.416 1.00 87.66  ? 585  SER B O   1 
ATOM   3955  C CB  . SER A 1 553 ? 192.685 230.665 203.712 1.00 116.76 ? 585  SER B CB  1 
ATOM   3956  O OG  . SER A 1 553 ? 192.041 229.807 204.633 1.00 116.76 ? 585  SER B OG  1 
ATOM   3957  N N   . PRO A 1 554 ? 190.751 232.943 204.641 1.00 88.29  ? 586  PRO B N   1 
ATOM   3958  C CA  . PRO A 1 554 ? 189.553 233.367 205.348 1.00 88.29  ? 586  PRO B CA  1 
ATOM   3959  C C   . PRO A 1 554 ? 188.983 232.321 206.286 1.00 88.29  ? 586  PRO B C   1 
ATOM   3960  O O   . PRO A 1 554 ? 188.186 232.659 207.158 1.00 88.29  ? 586  PRO B O   1 
ATOM   3961  C CB  . PRO A 1 554 ? 188.572 233.662 204.210 1.00 150.87 ? 586  PRO B CB  1 
ATOM   3962  C CG  . PRO A 1 554 ? 189.439 234.044 203.046 1.00 150.87 ? 586  PRO B CG  1 
ATOM   3963  C CD  . PRO A 1 554 ? 190.685 233.203 203.176 1.00 150.87 ? 586  PRO B CD  1 
ATOM   3964  N N   . TRP A 1 555 ? 189.332 231.054 206.096 1.00 89.84  ? 587  TRP B N   1 
ATOM   3965  C CA  . TRP A 1 555 ? 188.797 230.041 206.967 1.00 89.84  ? 587  TRP B CA  1 
ATOM   3966  C C   . TRP A 1 555 ? 189.886 229.521 207.889 1.00 89.84  ? 587  TRP B C   1 
ATOM   3967  O O   . TRP A 1 555 ? 189.638 229.239 209.059 1.00 89.84  ? 587  TRP B O   1 
ATOM   3968  C CB  . TRP A 1 555 ? 188.255 228.917 206.119 1.00 120.28 ? 587  TRP B CB  1 
ATOM   3969  C CG  . TRP A 1 555 ? 187.303 229.447 205.180 1.00 120.28 ? 587  TRP B CG  1 
ATOM   3970  C CD1 . TRP A 1 555 ? 185.982 229.654 205.354 1.00 120.28 ? 587  TRP B CD1 1 
ATOM   3971  C CD2 . TRP A 1 555 ? 187.611 229.882 203.860 1.00 120.28 ? 587  TRP B CD2 1 
ATOM   3972  N NE1 . TRP A 1 555 ? 185.450 230.194 204.230 1.00 120.28 ? 587  TRP B NE1 1 
ATOM   3973  C CE2 . TRP A 1 555 ? 186.440 230.340 203.306 1.00 120.28 ? 587  TRP B CE2 1 
ATOM   3974  C CE3 . TRP A 1 555 ? 188.780 229.914 203.114 1.00 120.28 ? 587  TRP B CE3 1 
ATOM   3975  C CZ2 . TRP A 1 555 ? 186.394 230.835 202.038 1.00 120.28 ? 587  TRP B CZ2 1 
ATOM   3976  C CZ3 . TRP A 1 555 ? 188.734 230.402 201.848 1.00 120.28 ? 587  TRP B CZ3 1 
ATOM   3977  C CH2 . TRP A 1 555 ? 187.574 230.855 201.318 1.00 120.28 ? 587  TRP B CH2 1 
ATOM   3978  N N   . ALA A 1 556 ? 191.119 229.433 207.383 1.00 91.29  ? 588  ALA B N   1 
ATOM   3979  C CA  . ALA A 1 556 ? 192.248 228.921 208.155 1.00 91.29  ? 588  ALA B CA  1 
ATOM   3980  C C   . ALA A 1 556 ? 192.547 229.808 209.340 1.00 91.29  ? 588  ALA B C   1 
ATOM   3981  O O   . ALA A 1 556 ? 192.942 229.320 210.403 1.00 91.29  ? 588  ALA B O   1 
ATOM   3982  C CB  . ALA A 1 556 ? 193.465 228.798 207.296 1.00 123.33 ? 588  ALA B CB  1 
ATOM   3983  N N   . VAL A 1 557 ? 192.287 231.100 209.190 1.00 92.39  ? 589  VAL B N   1 
ATOM   3984  C CA  . VAL A 1 557 ? 192.532 232.009 210.281 1.00 92.39  ? 589  VAL B CA  1 
ATOM   3985  C C   . VAL A 1 557 ? 191.710 231.699 211.507 1.00 92.39  ? 589  VAL B C   1 
ATOM   3986  O O   . VAL A 1 557 ? 192.094 232.083 212.606 1.00 92.39  ? 589  VAL B O   1 
ATOM   3987  C CB  . VAL A 1 557 ? 192.270 233.482 209.901 1.00 130.11 ? 589  VAL B CB  1 
ATOM   3988  C CG1 . VAL A 1 557 ? 193.258 233.924 208.910 1.00 130.11 ? 589  VAL B CG1 1 
ATOM   3989  C CG2 . VAL A 1 557 ? 190.850 233.629 209.319 1.00 130.11 ? 589  VAL B CG2 1 
ATOM   3990  N N   . LEU A 1 558 ? 190.543 231.083 211.373 1.00 91.65  ? 590  LEU B N   1 
ATOM   3991  C CA  . LEU A 1 558 ? 189.810 230.862 212.582 1.00 91.65  ? 590  LEU B CA  1 
ATOM   3992  C C   . LEU A 1 558 ? 190.601 229.968 213.544 1.00 91.65  ? 590  LEU B C   1 
ATOM   3993  O O   . LEU A 1 558 ? 191.044 230.473 214.576 1.00 91.65  ? 590  LEU B O   1 
ATOM   3994  C CB  . LEU A 1 558 ? 188.389 230.356 212.260 1.00 130.27 ? 590  LEU B CB  1 
ATOM   3995  C CG  . LEU A 1 558 ? 187.511 229.956 213.452 1.00 130.27 ? 590  LEU B CG  1 
ATOM   3996  C CD1 . LEU A 1 558 ? 187.269 231.173 214.356 1.00 130.27 ? 590  LEU B CD1 1 
ATOM   3997  C CD2 . LEU A 1 558 ? 186.196 229.378 212.944 1.00 130.27 ? 590  LEU B CD2 1 
ATOM   3998  N N   . PRO A 1 559 ? 190.924 228.693 213.232 1.00 94.76  ? 591  PRO B N   1 
ATOM   3999  C CA  . PRO A 1 559 ? 191.711 227.852 214.095 1.00 94.76  ? 591  PRO B CA  1 
ATOM   4000  C C   . PRO A 1 559 ? 193.116 228.364 214.271 1.00 94.76  ? 591  PRO B C   1 
ATOM   4001  O O   . PRO A 1 559 ? 193.716 228.156 215.325 1.00 94.76  ? 591  PRO B O   1 
ATOM   4002  C CB  . PRO A 1 559 ? 191.702 226.507 213.379 1.00 161.92 ? 591  PRO B CB  1 
ATOM   4003  C CG  . PRO A 1 559 ? 191.402 226.831 211.957 1.00 161.92 ? 591  PRO B CG  1 
ATOM   4004  C CD  . PRO A 1 559 ? 190.478 228.018 212.016 1.00 161.92 ? 591  PRO B CD  1 
ATOM   4005  N N   . LEU A 1 560 ? 193.619 229.161 213.322 1.00 95.11  ? 592  LEU B N   1 
ATOM   4006  C CA  . LEU A 1 560 ? 194.951 229.677 213.497 1.00 95.11  ? 592  LEU B CA  1 
ATOM   4007  C C   . LEU A 1 560 ? 194.999 230.477 214.767 1.00 95.11  ? 592  LEU B C   1 
ATOM   4008  O O   . LEU A 1 560 ? 195.984 230.433 215.498 1.00 95.11  ? 592  LEU B O   1 
ATOM   4009  C CB  . LEU A 1 560 ? 195.324 230.638 212.367 1.00 135.18 ? 592  LEU B CB  1 
ATOM   4010  C CG  . LEU A 1 560 ? 196.756 231.225 212.365 1.00 135.18 ? 592  LEU B CG  1 
ATOM   4011  C CD1 . LEU A 1 560 ? 197.789 230.119 212.169 1.00 135.18 ? 592  LEU B CD1 1 
ATOM   4012  C CD2 . LEU A 1 560 ? 196.852 232.282 211.281 1.00 135.18 ? 592  LEU B CD2 1 
ATOM   4013  N N   . PHE A 1 561 ? 193.941 231.236 215.041 1.00 95.34  ? 593  PHE B N   1 
ATOM   4014  C CA  . PHE A 1 561 ? 193.967 232.036 216.234 1.00 95.34  ? 593  PHE B CA  1 
ATOM   4015  C C   . PHE A 1 561 ? 193.259 231.348 217.382 1.00 95.34  ? 593  PHE B C   1 
ATOM   4016  O O   . PHE A 1 561 ? 193.621 231.582 218.535 1.00 95.34  ? 593  PHE B O   1 
ATOM   4017  C CB  . PHE A 1 561 ? 193.373 233.415 215.967 1.00 128.93 ? 593  PHE B CB  1 
ATOM   4018  C CG  . PHE A 1 561 ? 194.223 234.260 215.014 1.00 128.93 ? 593  PHE B CG  1 
ATOM   4019  C CD1 . PHE A 1 561 ? 195.439 234.796 215.428 1.00 128.93 ? 593  PHE B CD1 1 
ATOM   4020  C CD2 . PHE A 1 561 ? 193.812 234.506 213.705 1.00 128.93 ? 593  PHE B CD2 1 
ATOM   4021  C CE1 . PHE A 1 561 ? 196.212 235.550 214.561 1.00 128.93 ? 593  PHE B CE1 1 
ATOM   4022  C CE2 . PHE A 1 561 ? 194.584 235.257 212.843 1.00 128.93 ? 593  PHE B CE2 1 
ATOM   4023  C CZ  . PHE A 1 561 ? 195.782 235.778 213.270 1.00 128.93 ? 593  PHE B CZ  1 
ATOM   4024  N N   . LEU A 1 562 ? 192.286 230.475 217.109 1.00 95.80  ? 594  LEU B N   1 
ATOM   4025  C CA  . LEU A 1 562 ? 191.593 229.849 218.222 1.00 95.80  ? 594  LEU B CA  1 
ATOM   4026  C C   . LEU A 1 562 ? 192.540 228.948 218.961 1.00 95.80  ? 594  LEU B C   1 
ATOM   4027  O O   . LEU A 1 562 ? 192.463 228.833 220.182 1.00 95.80  ? 594  LEU B O   1 
ATOM   4028  C CB  . LEU A 1 562 ? 190.423 228.976 217.785 1.00 136.17 ? 594  LEU B CB  1 
ATOM   4029  C CG  . LEU A 1 562 ? 189.199 229.637 217.168 1.00 136.17 ? 594  LEU B CG  1 
ATOM   4030  C CD1 . LEU A 1 562 ? 188.284 228.519 216.688 1.00 136.17 ? 594  LEU B CD1 1 
ATOM   4031  C CD2 . LEU A 1 562 ? 188.500 230.530 218.170 1.00 136.17 ? 594  LEU B CD2 1 
ATOM   4032  N N   . ALA A 1 563 ? 193.422 228.276 218.223 1.00 96.23  ? 595  ALA B N   1 
ATOM   4033  C CA  . ALA A 1 563 ? 194.376 227.375 218.820 1.00 96.23  ? 595  ALA B CA  1 
ATOM   4034  C C   . ALA A 1 563 ? 195.323 228.130 219.729 1.00 96.23  ? 595  ALA B C   1 
ATOM   4035  O O   . ALA A 1 563 ? 195.720 227.611 220.768 1.00 96.23  ? 595  ALA B O   1 
ATOM   4036  C CB  . ALA A 1 563 ? 195.143 226.651 217.747 1.00 130.00 ? 595  ALA B CB  1 
ATOM   4037  N N   . VAL A 1 564 ? 195.664 229.360 219.359 1.00 97.10  ? 596  VAL B N   1 
ATOM   4038  C CA  . VAL A 1 564 ? 196.559 230.186 220.143 1.00 97.10  ? 596  VAL B CA  1 
ATOM   4039  C C   . VAL A 1 564 ? 195.871 230.581 221.419 1.00 97.10  ? 596  VAL B C   1 
ATOM   4040  O O   . VAL A 1 564 ? 196.480 230.560 222.491 1.00 97.10  ? 596  VAL B O   1 
ATOM   4041  C CB  . VAL A 1 564 ? 196.987 231.423 219.360 1.00 136.74 ? 596  VAL B CB  1 
ATOM   4042  C CG1 . VAL A 1 564 ? 197.787 232.371 220.253 1.00 136.74 ? 596  VAL B CG1 1 
ATOM   4043  C CG2 . VAL A 1 564 ? 197.804 230.967 218.176 1.00 136.74 ? 596  VAL B CG2 1 
ATOM   4044  N N   . VAL A 1 565 ? 194.600 230.947 221.296 1.00 97.23  ? 597  VAL B N   1 
ATOM   4045  C CA  . VAL A 1 565 ? 193.808 231.303 222.448 1.00 97.23  ? 597  VAL B CA  1 
ATOM   4046  C C   . VAL A 1 565 ? 193.699 230.102 223.353 1.00 97.23  ? 597  VAL B C   1 
ATOM   4047  O O   . VAL A 1 565 ? 193.763 230.245 224.573 1.00 97.23  ? 597  VAL B O   1 
ATOM   4048  C CB  . VAL A 1 565 ? 192.409 231.776 222.045 1.00 136.92 ? 597  VAL B CB  1 
ATOM   4049  C CG1 . VAL A 1 565 ? 191.525 231.938 223.291 1.00 136.92 ? 597  VAL B CG1 1 
ATOM   4050  C CG2 . VAL A 1 565 ? 192.536 233.092 221.311 1.00 136.92 ? 597  VAL B CG2 1 
ATOM   4051  N N   . GLY A 1 566 ? 193.494 228.930 222.759 1.00 97.10  ? 598  GLY B N   1 
ATOM   4052  C CA  . GLY A 1 566 ? 193.394 227.687 223.478 1.00 97.10  ? 598  GLY B CA  1 
ATOM   4053  C C   . GLY A 1 566 ? 194.661 227.441 224.280 1.00 97.10  ? 598  GLY B C   1 
ATOM   4054  O O   . GLY A 1 566 ? 194.581 227.110 225.470 1.00 97.10  ? 598  GLY B O   1 
ATOM   4055  N N   . ILE A 1 567 ? 195.830 227.641 223.662 1.00 97.78  ? 599  ILE B N   1 
ATOM   4056  C CA  . ILE A 1 567 ? 197.079 227.483 224.383 1.00 97.78  ? 599  ILE B CA  1 
ATOM   4057  C C   . ILE A 1 567 ? 197.180 228.505 225.492 1.00 97.78  ? 599  ILE B C   1 
ATOM   4058  O O   . ILE A 1 567 ? 197.595 228.158 226.596 1.00 97.78  ? 599  ILE B O   1 
ATOM   4059  C CB  . ILE A 1 567 ? 198.319 227.611 223.463 1.00 138.98 ? 599  ILE B CB  1 
ATOM   4060  C CG1 . ILE A 1 567 ? 198.394 226.436 222.423 1.00 138.98 ? 599  ILE B CG1 1 
ATOM   4061  C CG2 . ILE A 1 567 ? 199.597 227.691 224.312 1.00 138.98 ? 599  ILE B CG2 1 
ATOM   4062  C CD1 . ILE A 1 567 ? 198.590 225.039 222.984 1.00 138.98 ? 599  ILE B CD1 1 
ATOM   4063  N N   . ALA A 1 568 ? 196.825 229.759 225.222 1.00 97.63  ? 600  ALA B N   1 
ATOM   4064  C CA  . ALA A 1 568 ? 196.911 230.767 226.257 1.00 97.63  ? 600  ALA B CA  1 
ATOM   4065  C C   . ALA A 1 568 ? 196.006 230.443 227.439 1.00 97.63  ? 600  ALA B C   1 
ATOM   4066  O O   . ALA A 1 568 ? 196.405 230.624 228.596 1.00 97.63  ? 600  ALA B O   1 
ATOM   4067  C CB  . ALA A 1 568 ? 196.526 232.112 225.680 1.00 131.89 ? 600  ALA B CB  1 
ATOM   4068  N N   . ALA A 1 569 ? 194.795 229.947 227.160 1.00 97.00  ? 601  ALA B N   1 
ATOM   4069  C CA  . ALA A 1 569 ? 193.864 229.579 228.209 1.00 97.00  ? 601  ALA B CA  1 
ATOM   4070  C C   . ALA A 1 569 ? 194.389 228.399 228.988 1.00 97.00  ? 601  ALA B C   1 
ATOM   4071  O O   . ALA A 1 569 ? 194.290 228.362 230.218 1.00 97.00  ? 601  ALA B O   1 
ATOM   4072  C CB  . ALA A 1 569 ? 192.514 229.232 227.616 1.00 131.04 ? 601  ALA B CB  1 
ATOM   4073  N N   . THR A 1 570 ? 194.999 227.458 228.273 1.00 96.91  ? 602  THR B N   1 
ATOM   4074  C CA  . THR A 1 570 ? 195.536 226.270 228.885 1.00 96.91  ? 602  THR B CA  1 
ATOM   4075  C C   . THR A 1 570 ? 196.659 226.663 229.807 1.00 96.91  ? 602  THR B C   1 
ATOM   4076  O O   . THR A 1 570 ? 196.738 226.158 230.922 1.00 96.91  ? 602  THR B O   1 
ATOM   4077  C CB  . THR A 1 570 ? 196.072 225.276 227.832 1.00 132.66 ? 602  THR B CB  1 
ATOM   4078  O OG1 . THR A 1 570 ? 195.015 224.894 226.948 1.00 132.66 ? 602  THR B OG1 1 
ATOM   4079  C CG2 . THR A 1 570 ? 196.600 224.003 228.530 1.00 132.66 ? 602  THR B CG2 1 
ATOM   4080  N N   . LEU A 1 571 ? 197.535 227.557 229.354 1.00 97.16  ? 603  LEU B N   1 
ATOM   4081  C CA  . LEU A 1 571 ? 198.644 227.963 230.177 1.00 97.16  ? 603  LEU B CA  1 
ATOM   4082  C C   . LEU A 1 571 ? 198.163 228.750 231.380 1.00 97.16  ? 603  LEU B C   1 
ATOM   4083  O O   . LEU A 1 571 ? 198.645 228.525 232.479 1.00 97.16  ? 603  LEU B O   1 
ATOM   4084  C CB  . LEU A 1 571 ? 199.669 228.721 229.351 1.00 138.10 ? 603  LEU B CB  1 
ATOM   4085  C CG  . LEU A 1 571 ? 200.437 227.862 228.293 1.00 138.10 ? 603  LEU B CG  1 
ATOM   4086  C CD1 . LEU A 1 571 ? 201.262 228.784 227.440 1.00 138.10 ? 603  LEU B CD1 1 
ATOM   4087  C CD2 . LEU A 1 571 ? 201.341 226.810 228.982 1.00 138.10 ? 603  LEU B CD2 1 
ATOM   4088  N N   . PHE A 1 572 ? 197.121 229.573 231.240 1.00 97.14  ? 604  PHE B N   1 
ATOM   4089  C CA  . PHE A 1 572 ? 196.592 230.296 232.398 1.00 97.14  ? 604  PHE B CA  1 
ATOM   4090  C C   . PHE A 1 572 ? 196.290 229.270 233.492 1.00 97.14  ? 604  PHE B C   1 
ATOM   4091  O O   . PHE A 1 572 ? 196.670 229.440 234.668 1.00 97.14  ? 604  PHE B O   1 
ATOM   4092  C CB  . PHE A 1 572 ? 195.320 231.057 232.001 1.00 131.37 ? 604  PHE B CB  1 
ATOM   4093  C CG  . PHE A 1 572 ? 194.613 231.806 233.101 1.00 131.37 ? 604  PHE B CG  1 
ATOM   4094  C CD1 . PHE A 1 572 ? 195.041 233.065 233.505 1.00 131.37 ? 604  PHE B CD1 1 
ATOM   4095  C CD2 . PHE A 1 572 ? 193.497 231.257 233.721 1.00 131.37 ? 604  PHE B CD2 1 
ATOM   4096  C CE1 . PHE A 1 572 ? 194.372 233.754 234.503 1.00 131.37 ? 604  PHE B CE1 1 
ATOM   4097  C CE2 . PHE A 1 572 ? 192.831 231.946 234.715 1.00 131.37 ? 604  PHE B CE2 1 
ATOM   4098  C CZ  . PHE A 1 572 ? 193.269 233.194 235.105 1.00 131.37 ? 604  PHE B CZ  1 
ATOM   4099  N N   . VAL A 1 573 ? 195.618 228.191 233.084 1.00 95.36  ? 605  VAL B N   1 
ATOM   4100  C CA  . VAL A 1 573 ? 195.293 227.108 233.983 1.00 95.36  ? 605  VAL B CA  1 
ATOM   4101  C C   . VAL A 1 573 ? 196.548 226.404 234.502 1.00 95.36  ? 605  VAL B C   1 
ATOM   4102  O O   . VAL A 1 573 ? 196.666 226.180 235.706 1.00 95.36  ? 605  VAL B O   1 
ATOM   4103  C CB  . VAL A 1 573 ? 194.385 226.092 233.258 1.00 134.29 ? 605  VAL B CB  1 
ATOM   4104  C CG1 . VAL A 1 573 ? 194.203 224.835 234.091 1.00 134.29 ? 605  VAL B CG1 1 
ATOM   4105  C CG2 . VAL A 1 573 ? 193.010 226.767 232.921 1.00 134.29 ? 605  VAL B CG2 1 
ATOM   4106  N N   . VAL A 1 574 ? 197.504 226.105 233.632 1.00 94.67  ? 606  VAL B N   1 
ATOM   4107  C CA  . VAL A 1 574 ? 198.707 225.418 234.071 1.00 94.67  ? 606  VAL B CA  1 
ATOM   4108  C C   . VAL A 1 574 ? 199.478 226.219 235.081 1.00 94.67  ? 606  VAL B C   1 
ATOM   4109  O O   . VAL A 1 574 ? 199.951 225.650 236.058 1.00 94.67  ? 606  VAL B O   1 
ATOM   4110  C CB  . VAL A 1 574 ? 199.640 225.091 232.895 1.00 133.32 ? 606  VAL B CB  1 
ATOM   4111  C CG1 . VAL A 1 574 ? 201.001 224.576 233.400 1.00 133.32 ? 606  VAL B CG1 1 
ATOM   4112  C CG2 . VAL A 1 574 ? 198.989 224.026 232.028 1.00 133.32 ? 606  VAL B CG2 1 
ATOM   4113  N N   . ILE A 1 575 ? 199.621 227.515 234.862 1.00 94.89  ? 607  ILE B N   1 
ATOM   4114  C CA  . ILE A 1 575 ? 200.373 228.338 235.775 1.00 94.89  ? 607  ILE B CA  1 
ATOM   4115  C C   . ILE A 1 575 ? 199.719 228.323 237.131 1.00 94.89  ? 607  ILE B C   1 
ATOM   4116  O O   . ILE A 1 575 ? 200.422 228.214 238.138 1.00 94.89  ? 607  ILE B O   1 
ATOM   4117  C CB  . ILE A 1 575 ? 200.487 229.781 235.248 1.00 30.00  ? 607  ILE B CB  1 
ATOM   4118  C CG1 . ILE A 1 575 ? 201.337 229.819 233.976 1.00 30.00  ? 607  ILE B CG1 1 
ATOM   4119  C CG2 . ILE A 1 575 ? 201.074 230.693 236.314 1.00 30.00  ? 607  ILE B CG2 1 
ATOM   4120  C CD1 . ILE A 1 575 ? 201.285 231.143 233.248 1.00 30.00  ? 607  ILE B CD1 1 
ATOM   4121  N N   . THR A 1 576 ? 198.393 228.432 237.179 1.00 93.43  ? 608  THR B N   1 
ATOM   4122  C CA  . THR A 1 576 ? 197.723 228.375 238.462 1.00 93.43  ? 608  THR B CA  1 
ATOM   4123  C C   . THR A 1 576 ? 197.987 227.032 239.128 1.00 93.43  ? 608  THR B C   1 
ATOM   4124  O O   . THR A 1 576 ? 198.326 226.977 240.307 1.00 93.43  ? 608  THR B O   1 
ATOM   4125  C CB  . THR A 1 576 ? 196.212 228.582 238.317 1.00 127.90 ? 608  THR B CB  1 
ATOM   4126  O OG1 . THR A 1 576 ? 195.968 229.881 237.768 1.00 127.90 ? 608  THR B OG1 1 
ATOM   4127  C CG2 . THR A 1 576 ? 195.546 228.470 239.704 1.00 127.90 ? 608  THR B CG2 1 
ATOM   4128  N N   . PHE A 1 577 ? 197.880 225.945 238.384 1.00 92.82  ? 609  PHE B N   1 
ATOM   4129  C CA  . PHE A 1 577 ? 198.113 224.648 238.983 1.00 92.82  ? 609  PHE B CA  1 
ATOM   4130  C C   . PHE A 1 577 ? 199.532 224.511 239.497 1.00 92.82  ? 609  PHE B C   1 
ATOM   4131  O O   . PHE A 1 577 ? 199.735 223.988 240.590 1.00 92.82  ? 609  PHE B O   1 
ATOM   4132  C CB  . PHE A 1 577 ? 197.736 223.553 238.001 1.00 125.52 ? 609  PHE B CB  1 
ATOM   4133  C CG  . PHE A 1 577 ? 196.288 223.192 238.113 1.00 125.52 ? 609  PHE B CG  1 
ATOM   4134  C CD1 . PHE A 1 577 ? 195.265 223.939 237.574 1.00 125.52 ? 609  PHE B CD1 1 
ATOM   4135  C CD2 . PHE A 1 577 ? 195.966 222.063 238.789 1.00 125.52 ? 609  PHE B CD2 1 
ATOM   4136  C CE1 . PHE A 1 577 ? 193.966 223.547 237.736 1.00 125.52 ? 609  PHE B CE1 1 
ATOM   4137  C CE2 . PHE A 1 577 ? 194.665 221.665 238.959 1.00 125.52 ? 609  PHE B CE2 1 
ATOM   4138  C CZ  . PHE A 1 577 ? 193.660 222.416 238.428 1.00 125.52 ? 609  PHE B CZ  1 
ATOM   4139  N N   . VAL A 1 578 ? 200.509 225.025 238.754 1.00 91.85  ? 610  VAL B N   1 
ATOM   4140  C CA  . VAL A 1 578 ? 201.888 224.951 239.196 1.00 91.85  ? 610  VAL B CA  1 
ATOM   4141  C C   . VAL A 1 578 ? 202.111 225.770 240.467 1.00 91.85  ? 610  VAL B C   1 
ATOM   4142  O O   . VAL A 1 578 ? 202.726 225.288 241.424 1.00 91.85  ? 610  VAL B O   1 
ATOM   4143  C CB  . VAL A 1 578 ? 202.858 225.391 238.085 1.00 129.35 ? 610  VAL B CB  1 
ATOM   4144  C CG1 . VAL A 1 578 ? 204.291 225.510 238.635 1.00 129.35 ? 610  VAL B CG1 1 
ATOM   4145  C CG2 . VAL A 1 578 ? 202.834 224.347 236.973 1.00 129.35 ? 610  VAL B CG2 1 
ATOM   4146  N N   . ARG A 1 579 ? 201.566 226.989 240.517 1.00 92.15  ? 611  ARG B N   1 
ATOM   4147  C CA  . ARG A 1 579 ? 201.728 227.843 241.690 1.00 92.15  ? 611  ARG B CA  1 
ATOM   4148  C C   . ARG A 1 579 ? 201.151 227.183 242.929 1.00 92.15  ? 611  ARG B C   1 
ATOM   4149  O O   . ARG A 1 579 ? 201.686 227.318 244.031 1.00 92.15  ? 611  ARG B O   1 
ATOM   4150  C CB  . ARG A 1 579 ? 201.034 229.180 241.487 1.00 129.42 ? 611  ARG B CB  1 
ATOM   4151  C CG  . ARG A 1 579 ? 201.702 230.128 240.518 1.00 129.42 ? 611  ARG B CG  1 
ATOM   4152  C CD  . ARG A 1 579 ? 200.871 231.331 240.292 1.00 129.42 ? 611  ARG B CD  1 
ATOM   4153  N NE  . ARG A 1 579 ? 201.521 232.277 239.396 1.00 129.42 ? 611  ARG B NE  1 
ATOM   4154  C CZ  . ARG A 1 579 ? 200.936 233.365 238.846 1.00 129.42 ? 611  ARG B CZ  1 
ATOM   4155  N NH1 . ARG A 1 579 ? 201.642 234.152 238.048 1.00 129.42 ? 611  ARG B NH1 1 
ATOM   4156  N NH2 . ARG A 1 579 ? 199.674 233.645 239.094 1.00 129.42 ? 611  ARG B NH2 1 
ATOM   4157  N N   . TYR A 1 580 ? 200.084 226.426 242.731 1.00 89.97  ? 612  TYR B N   1 
ATOM   4158  C CA  . TYR A 1 580 ? 199.378 225.736 243.780 1.00 89.97  ? 612  TYR B CA  1 
ATOM   4159  C C   . TYR A 1 580 ? 199.648 224.216 243.822 1.00 89.97  ? 612  TYR B C   1 
ATOM   4160  O O   . TYR A 1 580 ? 198.899 223.472 244.453 1.00 89.97  ? 612  TYR B O   1 
ATOM   4161  C CB  . TYR A 1 580 ? 197.897 226.088 243.654 1.00 120.77 ? 612  TYR B CB  1 
ATOM   4162  C CG  . TYR A 1 580 ? 197.639 227.583 243.980 1.00 120.77 ? 612  TYR B CG  1 
ATOM   4163  C CD1 . TYR A 1 580 ? 197.404 227.962 245.278 1.00 120.77 ? 612  TYR B CD1 1 
ATOM   4164  C CD2 . TYR A 1 580 ? 197.634 228.566 242.980 1.00 120.77 ? 612  TYR B CD2 1 
ATOM   4165  C CE1 . TYR A 1 580 ? 197.184 229.292 245.571 1.00 120.77 ? 612  TYR B CE1 1 
ATOM   4166  C CE2 . TYR A 1 580 ? 197.411 229.878 243.274 1.00 120.77 ? 612  TYR B CE2 1 
ATOM   4167  C CZ  . TYR A 1 580 ? 197.188 230.245 244.573 1.00 120.77 ? 612  TYR B CZ  1 
ATOM   4168  O OH  . TYR A 1 580 ? 196.983 231.568 244.881 1.00 120.77 ? 612  TYR B OH  1 
ATOM   4169  N N   . ASN A 1 581 ? 200.777 223.747 243.264 1.00 86.67  ? 613  ASN B N   1 
ATOM   4170  C CA  . ASN A 1 581 ? 201.069 222.306 243.261 1.00 86.67  ? 613  ASN B CA  1 
ATOM   4171  C C   . ASN A 1 581 ? 201.077 221.614 244.613 1.00 86.67  ? 613  ASN B C   1 
ATOM   4172  O O   . ASN A 1 581 ? 200.749 220.434 244.690 1.00 86.67  ? 613  ASN B O   1 
ATOM   4173  C CB  . ASN A 1 581 ? 202.433 222.004 242.651 1.00 115.29 ? 613  ASN B CB  1 
ATOM   4174  C CG  . ASN A 1 581 ? 202.512 221.959 241.173 1.00 115.29 ? 613  ASN B CG  1 
ATOM   4175  O OD1 . ASN A 1 581 ? 201.526 221.730 240.457 1.00 115.29 ? 613  ASN B OD1 1 
ATOM   4176  N ND2 . ASN A 1 581 ? 203.714 222.145 240.677 1.00 115.29 ? 613  ASN B ND2 1 
ATOM   4177  N N   . ASP A 1 582 ? 201.472 222.296 245.679 1.00 84.70  ? 614  ASP B N   1 
ATOM   4178  C CA  . ASP A 1 582 ? 201.533 221.665 246.997 1.00 84.70  ? 614  ASP B CA  1 
ATOM   4179  C C   . ASP A 1 582 ? 200.340 222.022 247.879 1.00 84.70  ? 614  ASP B C   1 
ATOM   4180  O O   . ASP A 1 582 ? 200.349 221.761 249.087 1.00 84.70  ? 614  ASP B O   1 
ATOM   4181  C CB  . ASP A 1 582 ? 202.853 222.021 247.688 1.00 107.86 ? 614  ASP B CB  1 
ATOM   4182  C CG  . ASP A 1 582 ? 204.085 221.346 247.034 1.00 107.86 ? 614  ASP B CG  1 
ATOM   4183  O OD1 . ASP A 1 582 ? 204.077 220.124 246.894 1.00 107.86 ? 614  ASP B OD1 1 
ATOM   4184  O OD2 . ASP A 1 582 ? 205.002 222.048 246.677 1.00 107.86 ? 614  ASP B OD2 1 
ATOM   4185  N N   . THR A 1 583 ? 199.317 222.620 247.276 1.00 85.97  ? 615  THR B N   1 
ATOM   4186  C CA  . THR A 1 583 ? 198.103 223.017 247.964 1.00 85.97  ? 615  THR B CA  1 
ATOM   4187  C C   . THR A 1 583 ? 197.051 221.905 247.724 1.00 85.97  ? 615  THR B C   1 
ATOM   4188  O O   . THR A 1 583 ? 196.884 221.481 246.574 1.00 85.97  ? 615  THR B O   1 
ATOM   4189  C CB  . THR A 1 583 ? 197.621 224.400 247.450 1.00 117.68 ? 615  THR B CB  1 
ATOM   4190  O OG1 . THR A 1 583 ? 198.634 225.383 247.701 1.00 117.68 ? 615  THR B OG1 1 
ATOM   4191  C CG2 . THR A 1 583 ? 196.383 224.861 248.172 1.00 117.68 ? 615  THR B CG2 1 
ATOM   4192  N N   . PRO A 1 584 ? 196.304 221.431 248.757 1.00 84.14  ? 616  PRO B N   1 
ATOM   4193  C CA  . PRO A 1 584 ? 195.291 220.379 248.684 1.00 84.14  ? 616  PRO B CA  1 
ATOM   4194  C C   . PRO A 1 584 ? 194.281 220.539 247.558 1.00 84.14  ? 616  PRO B C   1 
ATOM   4195  O O   . PRO A 1 584 ? 193.853 219.553 246.963 1.00 84.14  ? 616  PRO B O   1 
ATOM   4196  C CB  . PRO A 1 584 ? 194.605 220.513 250.043 1.00 143.78 ? 616  PRO B CB  1 
ATOM   4197  C CG  . PRO A 1 584 ? 195.679 221.003 250.960 1.00 143.78 ? 616  PRO B CG  1 
ATOM   4198  C CD  . PRO A 1 584 ? 196.501 221.951 250.139 1.00 143.78 ? 616  PRO B CD  1 
ATOM   4199  N N   . ILE A 1 585 ? 193.944 221.767 247.186 1.00 83.87  ? 617  ILE B N   1 
ATOM   4200  C CA  . ILE A 1 585 ? 192.986 221.960 246.102 1.00 83.87  ? 617  ILE B CA  1 
ATOM   4201  C C   . ILE A 1 585 ? 193.466 221.366 244.770 1.00 83.87  ? 617  ILE B C   1 
ATOM   4202  O O   . ILE A 1 585 ? 192.657 221.114 243.875 1.00 83.87  ? 617  ILE B O   1 
ATOM   4203  C CB  . ILE A 1 585 ? 192.590 223.436 245.971 1.00 119.21 ? 617  ILE B CB  1 
ATOM   4204  C CG1 . ILE A 1 585 ? 191.305 223.537 245.072 1.00 119.21 ? 617  ILE B CG1 1 
ATOM   4205  C CG2 . ILE A 1 585 ? 193.746 224.272 245.434 1.00 119.21 ? 617  ILE B CG2 1 
ATOM   4206  C CD1 . ILE A 1 585 ? 190.546 224.857 245.130 1.00 119.21 ? 617  ILE B CD1 1 
ATOM   4207  N N   . VAL A 1 586 ? 194.780 221.212 244.615 1.00 86.49  ? 618  VAL B N   1 
ATOM   4208  C CA  . VAL A 1 586 ? 195.369 220.604 243.438 1.00 86.49  ? 618  VAL B CA  1 
ATOM   4209  C C   . VAL A 1 586 ? 195.671 219.136 243.696 1.00 86.49  ? 618  VAL B C   1 
ATOM   4210  O O   . VAL A 1 586 ? 195.350 218.264 242.887 1.00 86.49  ? 618  VAL B O   1 
ATOM   4211  C CB  . VAL A 1 586 ? 196.679 221.326 243.016 1.00 121.80 ? 618  VAL B CB  1 
ATOM   4212  C CG1 . VAL A 1 586 ? 197.361 220.557 241.873 1.00 121.80 ? 618  VAL B CG1 1 
ATOM   4213  C CG2 . VAL A 1 586 ? 196.351 222.763 242.553 1.00 121.80 ? 618  VAL B CG2 1 
ATOM   4214  N N   . LYS A 1 587 ? 196.278 218.856 244.841 1.00 84.50  ? 619  LYS B N   1 
ATOM   4215  C CA  . LYS A 1 587 ? 196.709 217.499 245.150 1.00 84.50  ? 619  LYS B CA  1 
ATOM   4216  C C   . LYS A 1 587 ? 195.541 216.516 245.181 1.00 84.50  ? 619  LYS B C   1 
ATOM   4217  O O   . LYS A 1 587 ? 195.666 215.366 244.758 1.00 84.50  ? 619  LYS B O   1 
ATOM   4218  C CB  . LYS A 1 587 ? 197.430 217.477 246.490 1.00 120.87 ? 619  LYS B CB  1 
ATOM   4219  C CG  . LYS A 1 587 ? 198.777 218.193 246.483 1.00 120.87 ? 619  LYS B CG  1 
ATOM   4220  C CD  . LYS A 1 587 ? 199.577 217.940 247.762 1.00 120.87 ? 619  LYS B CD  1 
ATOM   4221  C CE  . LYS A 1 587 ? 198.972 218.640 248.983 1.00 120.87 ? 619  LYS B CE  1 
ATOM   4222  N NZ  . LYS A 1 587 ? 199.855 218.517 250.184 1.00 120.87 ? 619  LYS B NZ  1 
ATOM   4223  N N   . ALA A 1 588 ? 194.390 216.990 245.642 1.00 79.74  ? 620  ALA B N   1 
ATOM   4224  C CA  . ALA A 1 588 ? 193.179 216.207 245.798 1.00 79.74  ? 620  ALA B CA  1 
ATOM   4225  C C   . ALA A 1 588 ? 192.647 215.562 244.535 1.00 79.74  ? 620  ALA B C   1 
ATOM   4226  O O   . ALA A 1 588 ? 192.001 214.519 244.620 1.00 79.74  ? 620  ALA B O   1 
ATOM   4227  C CB  . ALA A 1 588 ? 192.094 217.093 246.339 1.00 107.72 ? 620  ALA B CB  1 
ATOM   4228  N N   . SER A 1 589 ? 192.836 216.185 243.375 1.00 82.98  ? 621  SER B N   1 
ATOM   4229  C CA  . SER A 1 589 ? 192.287 215.625 242.149 1.00 82.98  ? 621  SER B CA  1 
ATOM   4230  C C   . SER A 1 589 ? 193.267 214.661 241.491 1.00 82.98  ? 621  SER B C   1 
ATOM   4231  O O   . SER A 1 589 ? 192.951 213.991 240.492 1.00 82.98  ? 621  SER B O   1 
ATOM   4232  C CB  . SER A 1 589 ? 191.922 216.735 241.186 1.00 110.53 ? 621  SER B CB  1 
ATOM   4233  O OG  . SER A 1 589 ? 193.057 217.402 240.713 1.00 110.53 ? 621  SER B OG  1 
ATOM   4234  N N   . GLY A 1 590 ? 194.477 214.615 242.033 1.00 84.05  ? 622  GLY B N   1 
ATOM   4235  C CA  . GLY A 1 590 ? 195.570 213.850 241.502 1.00 84.05  ? 622  GLY B CA  1 
ATOM   4236  C C   . GLY A 1 590 ? 196.430 214.839 240.771 1.00 84.05  ? 622  GLY B C   1 
ATOM   4237  O O   . GLY A 1 590 ? 196.110 215.242 239.647 1.00 84.05  ? 622  GLY B O   1 
ATOM   4238  N N   . ARG A 1 591 ? 197.529 215.244 241.391 1.00 87.35  ? 623  ARG B N   1 
ATOM   4239  C CA  . ARG A 1 591 ? 198.348 216.274 240.790 1.00 87.35  ? 623  ARG B CA  1 
ATOM   4240  C C   . ARG A 1 591 ? 198.938 215.811 239.472 1.00 87.35  ? 623  ARG B C   1 
ATOM   4241  O O   . ARG A 1 591 ? 199.002 216.575 238.502 1.00 87.35  ? 623  ARG B O   1 
ATOM   4242  C CB  . ARG A 1 591 ? 199.450 216.681 241.744 1.00 122.68 ? 623  ARG B CB  1 
ATOM   4243  C CG  . ARG A 1 591 ? 200.293 217.816 241.264 1.00 122.68 ? 623  ARG B CG  1 
ATOM   4244  C CD  . ARG A 1 591 ? 201.160 218.335 242.326 1.00 122.68 ? 623  ARG B CD  1 
ATOM   4245  N NE  . ARG A 1 591 ? 202.236 217.418 242.717 1.00 122.68 ? 623  ARG B NE  1 
ATOM   4246  C CZ  . ARG A 1 591 ? 203.051 217.610 243.789 1.00 122.68 ? 623  ARG B CZ  1 
ATOM   4247  N NH1 . ARG A 1 591 ? 204.032 216.755 244.040 1.00 122.68 ? 623  ARG B NH1 1 
ATOM   4248  N NH2 . ARG A 1 591 ? 202.867 218.657 244.572 1.00 122.68 ? 623  ARG B NH2 1 
ATOM   4249  N N   . GLU A 1 592 ? 199.356 214.559 239.443 1.00 90.00  ? 624  GLU B N   1 
ATOM   4250  C CA  . GLU A 1 592 ? 199.953 213.950 238.278 1.00 90.00  ? 624  GLU B CA  1 
ATOM   4251  C C   . GLU A 1 592 ? 198.900 213.700 237.196 1.00 90.00  ? 624  GLU B C   1 
ATOM   4252  O O   . GLU A 1 592 ? 199.185 213.802 236.002 1.00 90.00  ? 624  GLU B O   1 
ATOM   4253  C CB  . GLU A 1 592 ? 200.674 212.691 238.703 1.00 118.61 ? 624  GLU B CB  1 
ATOM   4254  C CG  . GLU A 1 592 ? 201.849 212.958 239.652 1.00 118.61 ? 624  GLU B CG  1 
ATOM   4255  C CD  . GLU A 1 592 ? 201.406 213.210 241.082 1.00 118.61 ? 624  GLU B CD  1 
ATOM   4256  O OE1 . GLU A 1 592 ? 200.227 213.040 241.364 1.00 118.61 ? 624  GLU B OE1 1 
ATOM   4257  O OE2 . GLU A 1 592 ? 202.222 213.603 241.880 1.00 118.61 ? 624  GLU B OE2 1 
ATOM   4258  N N   . LEU A 1 593 ? 197.677 213.364 237.613 1.00 91.54  ? 625  LEU B N   1 
ATOM   4259  C CA  . LEU A 1 593 ? 196.623 213.143 236.639 1.00 91.54  ? 625  LEU B CA  1 
ATOM   4260  C C   . LEU A 1 593 ? 196.292 214.476 235.978 1.00 91.54  ? 625  LEU B C   1 
ATOM   4261  O O   . LEU A 1 593 ? 196.082 214.544 234.760 1.00 91.54  ? 625  LEU B O   1 
ATOM   4262  C CB  . LEU A 1 593 ? 195.361 212.579 237.312 1.00 130.11 ? 625  LEU B CB  1 
ATOM   4263  C CG  . LEU A 1 593 ? 195.444 211.129 237.912 1.00 130.11 ? 625  LEU B CG  1 
ATOM   4264  C CD1 . LEU A 1 593 ? 194.154 210.846 238.682 1.00 130.11 ? 625  LEU B CD1 1 
ATOM   4265  C CD2 . LEU A 1 593 ? 195.625 210.067 236.799 1.00 130.11 ? 625  LEU B CD2 1 
ATOM   4266  N N   . SER A 1 594 ? 196.301 215.551 236.776 1.00 93.00  ? 626  SER B N   1 
ATOM   4267  C CA  . SER A 1 594 ? 196.033 216.874 236.251 1.00 93.00  ? 626  SER B CA  1 
ATOM   4268  C C   . SER A 1 594 ? 197.119 217.232 235.259 1.00 93.00  ? 626  SER B C   1 
ATOM   4269  O O   . SER A 1 594 ? 196.834 217.649 234.141 1.00 93.00  ? 626  SER B O   1 
ATOM   4270  C CB  . SER A 1 594 ? 195.978 217.898 237.356 1.00 123.87 ? 626  SER B CB  1 
ATOM   4271  O OG  . SER A 1 594 ? 195.714 219.161 236.834 1.00 123.87 ? 626  SER B OG  1 
ATOM   4272  N N   . TYR A 1 595 ? 198.376 216.955 235.621 1.00 94.86  ? 627  TYR B N   1 
ATOM   4273  C CA  . TYR A 1 595 ? 199.496 217.212 234.730 1.00 94.86  ? 627  TYR B CA  1 
ATOM   4274  C C   . TYR A 1 595 ? 199.289 216.592 233.372 1.00 94.86  ? 627  TYR B C   1 
ATOM   4275  O O   . TYR A 1 595 ? 199.453 217.268 232.347 1.00 94.86  ? 627  TYR B O   1 
ATOM   4276  C CB  . TYR A 1 595 ? 200.790 216.668 235.350 1.00 127.33 ? 627  TYR B CB  1 
ATOM   4277  C CG  . TYR A 1 595 ? 201.998 216.621 234.428 1.00 127.33 ? 627  TYR B CG  1 
ATOM   4278  C CD1 . TYR A 1 595 ? 202.753 217.746 234.163 1.00 127.33 ? 627  TYR B CD1 1 
ATOM   4279  C CD2 . TYR A 1 595 ? 202.350 215.402 233.859 1.00 127.33 ? 627  TYR B CD2 1 
ATOM   4280  C CE1 . TYR A 1 595 ? 203.855 217.651 233.326 1.00 127.33 ? 627  TYR B CE1 1 
ATOM   4281  C CE2 . TYR A 1 595 ? 203.441 215.307 233.029 1.00 127.33 ? 627  TYR B CE2 1 
ATOM   4282  C CZ  . TYR A 1 595 ? 204.195 216.425 232.761 1.00 127.33 ? 627  TYR B CZ  1 
ATOM   4283  O OH  . TYR A 1 595 ? 205.294 216.336 231.936 1.00 127.33 ? 627  TYR B OH  1 
ATOM   4284  N N   . VAL A 1 596 ? 198.919 215.313 233.334 1.00 95.62  ? 628  VAL B N   1 
ATOM   4285  C CA  . VAL A 1 596 ? 198.766 214.698 232.038 1.00 95.62  ? 628  VAL B CA  1 
ATOM   4286  C C   . VAL A 1 596 ? 197.574 215.288 231.290 1.00 95.62  ? 628  VAL B C   1 
ATOM   4287  O O   . VAL A 1 596 ? 197.685 215.521 230.080 1.00 95.62  ? 628  VAL B O   1 
ATOM   4288  C CB  . VAL A 1 596 ? 198.620 213.174 232.120 1.00 134.65 ? 628  VAL B CB  1 
ATOM   4289  C CG1 . VAL A 1 596 ? 198.334 212.631 230.700 1.00 134.65 ? 628  VAL B CG1 1 
ATOM   4290  C CG2 . VAL A 1 596 ? 199.894 212.567 232.696 1.00 134.65 ? 628  VAL B CG2 1 
ATOM   4291  N N   . LEU A 1 597 ? 196.444 215.527 231.963 1.00 94.96  ? 629  LEU B N   1 
ATOM   4292  C CA  . LEU A 1 597 ? 195.296 216.094 231.269 1.00 94.96  ? 629  LEU B CA  1 
ATOM   4293  C C   . LEU A 1 597 ? 195.607 217.455 230.697 1.00 94.96  ? 629  LEU B C   1 
ATOM   4294  O O   . LEU A 1 597 ? 195.229 217.736 229.555 1.00 94.96  ? 629  LEU B O   1 
ATOM   4295  C CB  . LEU A 1 597 ? 194.120 216.242 232.237 1.00 134.97 ? 629  LEU B CB  1 
ATOM   4296  C CG  . LEU A 1 597 ? 193.388 214.969 232.645 1.00 134.97 ? 629  LEU B CG  1 
ATOM   4297  C CD1 . LEU A 1 597 ? 192.494 215.255 233.841 1.00 134.97 ? 629  LEU B CD1 1 
ATOM   4298  C CD2 . LEU A 1 597 ? 192.489 214.509 231.471 1.00 134.97 ? 629  LEU B CD2 1 
ATOM   4299  N N   . LEU A 1 598 ? 196.315 218.287 231.437 1.00 96.66  ? 630  LEU B N   1 
ATOM   4300  C CA  . LEU A 1 598 ? 196.635 219.598 230.929 1.00 96.66  ? 630  LEU B CA  1 
ATOM   4301  C C   . LEU A 1 598 ? 197.597 219.502 229.766 1.00 96.66  ? 630  LEU B C   1 
ATOM   4302  O O   . LEU A 1 598 ? 197.458 220.251 228.794 1.00 96.66  ? 630  LEU B O   1 
ATOM   4303  C CB  . LEU A 1 598 ? 197.150 220.475 232.068 1.00 137.39 ? 630  LEU B CB  1 
ATOM   4304  C CG  . LEU A 1 598 ? 196.058 220.873 233.107 1.00 137.39 ? 630  LEU B CG  1 
ATOM   4305  C CD1 . LEU A 1 598 ? 196.682 221.520 234.351 1.00 137.39 ? 630  LEU B CD1 1 
ATOM   4306  C CD2 . LEU A 1 598 ? 195.087 221.870 232.460 1.00 137.39 ? 630  LEU B CD2 1 
ATOM   4307  N N   . ALA A 1 599 ? 198.559 218.574 229.831 1.00 95.91  ? 631  ALA B N   1 
ATOM   4308  C CA  . ALA A 1 599 ? 199.476 218.385 228.720 1.00 95.91  ? 631  ALA B CA  1 
ATOM   4309  C C   . ALA A 1 599 ? 198.703 217.940 227.485 1.00 95.91  ? 631  ALA B C   1 
ATOM   4310  O O   . ALA A 1 599 ? 198.973 218.398 226.373 1.00 95.91  ? 631  ALA B O   1 
ATOM   4311  C CB  . ALA A 1 599 ? 200.528 217.351 229.076 1.00 129.57 ? 631  ALA B CB  1 
ATOM   4312  N N   . GLY A 1 600 ? 197.696 217.092 227.696 1.00 95.87  ? 632  GLY B N   1 
ATOM   4313  C CA  . GLY A 1 600 ? 196.860 216.590 226.624 1.00 95.87  ? 632  GLY B CA  1 
ATOM   4314  C C   . GLY A 1 600 ? 196.129 217.720 225.928 1.00 95.87  ? 632  GLY B C   1 
ATOM   4315  O O   . GLY A 1 600 ? 196.170 217.804 224.699 1.00 95.87  ? 632  GLY B O   1 
ATOM   4316  N N   . ILE A 1 601 ? 195.526 218.606 226.723 1.00 96.37  ? 633  ILE B N   1 
ATOM   4317  C CA  . ILE A 1 601 ? 194.769 219.757 226.260 1.00 96.37  ? 633  ILE B CA  1 
ATOM   4318  C C   . ILE A 1 601 ? 195.671 220.698 225.480 1.00 96.37  ? 633  ILE B C   1 
ATOM   4319  O O   . ILE A 1 601 ? 195.284 221.209 224.423 1.00 96.37  ? 633  ILE B O   1 
ATOM   4320  C CB  . ILE A 1 601 ? 194.153 220.469 227.477 1.00 136.98 ? 633  ILE B CB  1 
ATOM   4321  C CG1 . ILE A 1 601 ? 193.048 219.565 228.098 1.00 136.98 ? 633  ILE B CG1 1 
ATOM   4322  C CG2 . ILE A 1 601 ? 193.619 221.816 227.109 1.00 136.98 ? 633  ILE B CG2 1 
ATOM   4323  C CD1 . ILE A 1 601 ? 192.578 219.971 229.495 1.00 136.98 ? 633  ILE B CD1 1 
ATOM   4324  N N   . PHE A 1 602 ? 196.868 220.945 226.010 1.00 97.14  ? 634  PHE B N   1 
ATOM   4325  C CA  . PHE A 1 602 ? 197.834 221.807 225.363 1.00 97.14  ? 634  PHE B CA  1 
ATOM   4326  C C   . PHE A 1 602 ? 198.130 221.267 223.981 1.00 97.14  ? 634  PHE B C   1 
ATOM   4327  O O   . PHE A 1 602 ? 198.077 221.996 222.986 1.00 97.14  ? 634  PHE B O   1 
ATOM   4328  C CB  . PHE A 1 602 ? 199.139 221.802 226.158 1.00 131.37 ? 634  PHE B CB  1 
ATOM   4329  C CG  . PHE A 1 602 ? 200.224 222.658 225.624 1.00 131.37 ? 634  PHE B CG  1 
ATOM   4330  C CD1 . PHE A 1 602 ? 201.101 222.178 224.655 1.00 131.37 ? 634  PHE B CD1 1 
ATOM   4331  C CD2 . PHE A 1 602 ? 200.375 223.964 226.078 1.00 131.37 ? 634  PHE B CD2 1 
ATOM   4332  C CE1 . PHE A 1 602 ? 202.096 222.976 224.160 1.00 131.37 ? 634  PHE B CE1 1 
ATOM   4333  C CE2 . PHE A 1 602 ? 201.388 224.756 225.585 1.00 131.37 ? 634  PHE B CE2 1 
ATOM   4334  C CZ  . PHE A 1 602 ? 202.242 224.269 224.629 1.00 131.37 ? 634  PHE B CZ  1 
ATOM   4335  N N   . LEU A 1 603 ? 198.421 219.973 223.911 1.00 95.34  ? 635  LEU B N   1 
ATOM   4336  C CA  . LEU A 1 603 ? 198.731 219.364 222.650 1.00 95.34  ? 635  LEU B CA  1 
ATOM   4337  C C   . LEU A 1 603 ? 197.538 219.355 221.734 1.00 95.34  ? 635  LEU B C   1 
ATOM   4338  O O   . LEU A 1 603 ? 197.689 219.586 220.538 1.00 95.34  ? 635  LEU B O   1 
ATOM   4339  C CB  . LEU A 1 603 ? 199.271 217.965 222.870 1.00 135.51 ? 635  LEU B CB  1 
ATOM   4340  C CG  . LEU A 1 603 ? 200.667 217.898 223.531 1.00 135.51 ? 635  LEU B CG  1 
ATOM   4341  C CD1 . LEU A 1 603 ? 200.956 216.464 223.888 1.00 135.51 ? 635  LEU B CD1 1 
ATOM   4342  C CD2 . LEU A 1 603 ? 201.751 218.448 222.570 1.00 135.51 ? 635  LEU B CD2 1 
ATOM   4343  N N   . CYS A 1 604 ? 196.328 219.171 222.257 1.00 95.29  ? 636  CYS B N   1 
ATOM   4344  C CA  . CYS A 1 604 ? 195.170 219.192 221.381 1.00 95.29  ? 636  CYS B CA  1 
ATOM   4345  C C   . CYS A 1 604 ? 195.190 220.471 220.574 1.00 95.29  ? 636  CYS B C   1 
ATOM   4346  O O   . CYS A 1 604 ? 195.079 220.448 219.348 1.00 95.29  ? 636  CYS B O   1 
ATOM   4347  C CB  . CYS A 1 604 ? 193.874 219.245 222.160 1.00 126.92 ? 636  CYS B CB  1 
ATOM   4348  S SG  . CYS A 1 604 ? 193.469 217.843 223.180 1.00 126.92 ? 636  CYS B SG  1 
ATOM   4349  N N   . TYR A 1 605 ? 195.416 221.592 221.252 1.00 96.77  ? 637  TYR B N   1 
ATOM   4350  C CA  . TYR A 1 605 ? 195.423 222.856 220.547 1.00 96.77  ? 637  TYR B CA  1 
ATOM   4351  C C   . TYR A 1 605 ? 196.676 223.036 219.693 1.00 96.77  ? 637  TYR B C   1 
ATOM   4352  O O   . TYR A 1 605 ? 196.611 223.583 218.589 1.00 96.77  ? 637  TYR B O   1 
ATOM   4353  C CB  . TYR A 1 605 ? 195.353 223.994 221.536 1.00 129.89 ? 637  TYR B CB  1 
ATOM   4354  C CG  . TYR A 1 605 ? 194.081 224.121 222.279 1.00 129.89 ? 637  TYR B CG  1 
ATOM   4355  C CD1 . TYR A 1 605 ? 192.901 224.410 221.622 1.00 129.89 ? 637  TYR B CD1 1 
ATOM   4356  C CD2 . TYR A 1 605 ? 194.095 223.973 223.651 1.00 129.89 ? 637  TYR B CD2 1 
ATOM   4357  C CE1 . TYR A 1 605 ? 191.744 224.572 222.354 1.00 129.89 ? 637  TYR B CE1 1 
ATOM   4358  C CE2 . TYR A 1 605 ? 192.942 224.138 224.363 1.00 129.89 ? 637  TYR B CE2 1 
ATOM   4359  C CZ  . TYR A 1 605 ? 191.776 224.441 223.712 1.00 129.89 ? 637  TYR B CZ  1 
ATOM   4360  O OH  . TYR A 1 605 ? 190.652 224.630 224.426 1.00 129.89 ? 637  TYR B OH  1 
ATOM   4361  N N   . ALA A 1 606 ? 197.828 222.569 220.175 1.00 95.35  ? 638  ALA B N   1 
ATOM   4362  C CA  . ALA A 1 606 ? 199.048 222.722 219.400 1.00 95.35  ? 638  ALA B CA  1 
ATOM   4363  C C   . ALA A 1 606 ? 198.927 221.969 218.082 1.00 95.35  ? 638  ALA B C   1 
ATOM   4364  O O   . ALA A 1 606 ? 199.394 222.432 217.035 1.00 95.35  ? 638  ALA B O   1 
ATOM   4365  C CB  . ALA A 1 606 ? 200.246 222.210 220.182 1.00 128.81 ? 638  ALA B CB  1 
ATOM   4366  N N   . THR A 1 607 ? 198.259 220.826 218.144 1.00 93.52  ? 639  THR B N   1 
ATOM   4367  C CA  . THR A 1 607 ? 198.057 219.961 217.014 1.00 93.52  ? 639  THR B CA  1 
ATOM   4368  C C   . THR A 1 607 ? 197.212 220.661 215.975 1.00 93.52  ? 639  THR B C   1 
ATOM   4369  O O   . THR A 1 607 ? 197.582 220.689 214.800 1.00 93.52  ? 639  THR B O   1 
ATOM   4370  C CB  . THR A 1 607 ? 197.337 218.665 217.458 1.00 128.02 ? 639  THR B CB  1 
ATOM   4371  O OG1 . THR A 1 607 ? 198.133 217.981 218.445 1.00 128.02 ? 639  THR B OG1 1 
ATOM   4372  C CG2 . THR A 1 607 ? 197.135 217.729 216.265 1.00 128.02 ? 639  THR B CG2 1 
ATOM   4373  N N   . THR A 1 608 ? 196.116 221.277 216.410 1.00 93.92  ? 640  THR B N   1 
ATOM   4374  C CA  . THR A 1 608 ? 195.220 221.936 215.483 1.00 93.92  ? 640  THR B CA  1 
ATOM   4375  C C   . THR A 1 608 ? 195.862 223.134 214.844 1.00 93.92  ? 640  THR B C   1 
ATOM   4376  O O   . THR A 1 608 ? 195.650 223.419 213.666 1.00 93.92  ? 640  THR B O   1 
ATOM   4377  C CB  . THR A 1 608 ? 193.942 222.353 216.196 1.00 128.57 ? 640  THR B CB  1 
ATOM   4378  O OG1 . THR A 1 608 ? 194.236 223.217 217.270 1.00 128.57 ? 640  THR B OG1 1 
ATOM   4379  C CG2 . THR A 1 608 ? 193.302 221.175 216.712 1.00 128.57 ? 640  THR B CG2 1 
ATOM   4380  N N   . PHE A 1 609 ? 196.715 223.812 215.585 1.00 94.86  ? 641  PHE B N   1 
ATOM   4381  C CA  . PHE A 1 609 ? 197.412 224.952 215.032 1.00 94.86  ? 641  PHE B CA  1 
ATOM   4382  C C   . PHE A 1 609 ? 198.266 224.445 213.873 1.00 94.86  ? 641  PHE B C   1 
ATOM   4383  O O   . PHE A 1 609 ? 198.214 224.964 212.756 1.00 94.86  ? 641  PHE B O   1 
ATOM   4384  C CB  . PHE A 1 609 ? 198.294 225.594 216.101 1.00 128.28 ? 641  PHE B CB  1 
ATOM   4385  C CG  . PHE A 1 609 ? 199.019 226.826 215.699 1.00 128.28 ? 641  PHE B CG  1 
ATOM   4386  C CD1 . PHE A 1 609 ? 198.360 228.051 215.660 1.00 128.28 ? 641  PHE B CD1 1 
ATOM   4387  C CD2 . PHE A 1 609 ? 200.371 226.786 215.383 1.00 128.28 ? 641  PHE B CD2 1 
ATOM   4388  C CE1 . PHE A 1 609 ? 199.031 229.197 215.321 1.00 128.28 ? 641  PHE B CE1 1 
ATOM   4389  C CE2 . PHE A 1 609 ? 201.044 227.943 215.038 1.00 128.28 ? 641  PHE B CE2 1 
ATOM   4390  C CZ  . PHE A 1 609 ? 200.368 229.152 215.010 1.00 128.28 ? 641  PHE B CZ  1 
ATOM   4391  N N   . LEU A 1 610 ? 199.002 223.364 214.130 1.00 92.57  ? 642  LEU B N   1 
ATOM   4392  C CA  . LEU A 1 610 ? 199.907 222.803 213.150 1.00 92.57  ? 642  LEU B CA  1 
ATOM   4393  C C   . LEU A 1 610 ? 199.219 222.079 211.989 1.00 92.57  ? 642  LEU B C   1 
ATOM   4394  O O   . LEU A 1 610 ? 199.821 221.948 210.922 1.00 92.57  ? 642  LEU B O   1 
ATOM   4395  C CB  . LEU A 1 610 ? 200.908 221.885 213.858 1.00 131.57 ? 642  LEU B CB  1 
ATOM   4396  C CG  . LEU A 1 610 ? 201.917 222.595 214.847 1.00 131.57 ? 642  LEU B CG  1 
ATOM   4397  C CD1 . LEU A 1 610 ? 202.695 221.531 215.597 1.00 131.57 ? 642  LEU B CD1 1 
ATOM   4398  C CD2 . LEU A 1 610 ? 202.889 223.521 214.076 1.00 131.57 ? 642  LEU B CD2 1 
ATOM   4399  N N   . MET A 1 611 ? 197.948 221.701 212.120 1.00 89.98  ? 643  MET B N   1 
ATOM   4400  C CA  . MET A 1 611 ? 197.236 221.048 211.019 1.00 89.98  ? 643  MET B CA  1 
ATOM   4401  C C   . MET A 1 611 ? 197.127 221.931 209.791 1.00 89.98  ? 643  MET B C   1 
ATOM   4402  O O   . MET A 1 611 ? 196.811 221.429 208.716 1.00 89.98  ? 643  MET B O   1 
ATOM   4403  C CB  . MET A 1 611 ? 195.823 220.663 211.395 1.00 125.18 ? 643  MET B CB  1 
ATOM   4404  C CG  . MET A 1 611 ? 195.662 219.551 212.370 1.00 125.18 ? 643  MET B CG  1 
ATOM   4405  S SD  . MET A 1 611 ? 193.952 219.287 212.743 1.00 125.18 ? 643  MET B SD  1 
ATOM   4406  C CE  . MET A 1 611 ? 193.977 218.400 214.288 1.00 125.18 ? 643  MET B CE  1 
ATOM   4407  N N   . ILE A 1 612 ? 197.333 223.236 209.946 1.00 91.23  ? 644  ILE B N   1 
ATOM   4408  C CA  . ILE A 1 612 ? 197.261 224.148 208.818 1.00 91.23  ? 644  ILE B CA  1 
ATOM   4409  C C   . ILE A 1 612 ? 198.641 224.727 208.495 1.00 91.23  ? 644  ILE B C   1 
ATOM   4410  O O   . ILE A 1 612 ? 198.743 225.736 207.795 1.00 91.23  ? 644  ILE B O   1 
ATOM   4411  C CB  . ILE A 1 612 ? 196.213 225.266 209.069 1.00 129.67 ? 644  ILE B CB  1 
ATOM   4412  C CG1 . ILE A 1 612 ? 196.577 226.068 210.344 1.00 129.67 ? 644  ILE B CG1 1 
ATOM   4413  C CG2 . ILE A 1 612 ? 194.811 224.655 209.171 1.00 129.67 ? 644  ILE B CG2 1 
ATOM   4414  C CD1 . ILE A 1 612 ? 195.772 227.355 210.573 1.00 129.67 ? 644  ILE B CD1 1 
ATOM   4415  N N   . ALA A 1 613 ? 199.693 224.085 209.019 1.00 90.97  ? 645  ALA B N   1 
ATOM   4416  C CA  . ALA A 1 613 ? 201.087 224.469 208.808 1.00 90.97  ? 645  ALA B CA  1 
ATOM   4417  C C   . ALA A 1 613 ? 201.528 224.205 207.381 1.00 90.97  ? 645  ALA B C   1 
ATOM   4418  O O   . ALA A 1 613 ? 201.063 223.263 206.738 1.00 90.97  ? 645  ALA B O   1 
ATOM   4419  C CB  . ALA A 1 613 ? 202.006 223.720 209.755 1.00 122.90 ? 645  ALA B CB  1 
ATOM   4420  N N   . GLU A 1 614 ? 202.469 225.015 206.913 1.00 89.04  ? 646  GLU B N   1 
ATOM   4421  C CA  . GLU A 1 614 ? 203.015 224.879 205.577 1.00 89.04  ? 646  GLU B CA  1 
ATOM   4422  C C   . GLU A 1 614 ? 203.576 223.462 205.353 1.00 89.04  ? 646  GLU B C   1 
ATOM   4423  O O   . GLU A 1 614 ? 204.330 222.961 206.203 1.00 89.04  ? 646  GLU B O   1 
ATOM   4424  C CB  . GLU A 1 614 ? 204.123 225.902 205.370 1.00 117.35 ? 646  GLU B CB  1 
ATOM   4425  C CG  . GLU A 1 614 ? 204.627 225.994 203.955 1.00 117.35 ? 646  GLU B CG  1 
ATOM   4426  C CD  . GLU A 1 614 ? 205.664 227.036 203.797 1.00 117.35 ? 646  GLU B CD  1 
ATOM   4427  O OE1 . GLU A 1 614 ? 206.137 227.527 204.787 1.00 117.35 ? 646  GLU B OE1 1 
ATOM   4428  O OE2 . GLU A 1 614 ? 205.957 227.395 202.674 1.00 117.35 ? 646  GLU B OE2 1 
ATOM   4429  N N   . PRO A 1 615 ? 203.227 222.791 204.232 1.00 88.19  ? 647  PRO B N   1 
ATOM   4430  C CA  . PRO A 1 615 ? 203.679 221.462 203.880 1.00 88.19  ? 647  PRO B CA  1 
ATOM   4431  C C   . PRO A 1 615 ? 205.183 221.331 203.856 1.00 88.19  ? 647  PRO B C   1 
ATOM   4432  O O   . PRO A 1 615 ? 205.881 222.184 203.310 1.00 88.19  ? 647  PRO B O   1 
ATOM   4433  C CB  . PRO A 1 615 ? 203.121 221.284 202.466 1.00 150.70 ? 647  PRO B CB  1 
ATOM   4434  C CG  . PRO A 1 615 ? 201.902 222.158 202.424 1.00 150.70 ? 647  PRO B CG  1 
ATOM   4435  C CD  . PRO A 1 615 ? 202.251 223.357 203.265 1.00 150.70 ? 647  PRO B CD  1 
ATOM   4436  N N   . ASP A 1 616 ? 205.640 220.242 204.445 1.00 88.30  ? 648  ASP B N   1 
ATOM   4437  C CA  . ASP A 1 616 ? 207.028 219.823 204.563 1.00 88.30  ? 648  ASP B CA  1 
ATOM   4438  C C   . ASP A 1 616 ? 207.010 218.368 204.979 1.00 88.30  ? 648  ASP B C   1 
ATOM   4439  O O   . ASP A 1 616 ? 205.944 217.824 205.279 1.00 88.30  ? 648  ASP B O   1 
ATOM   4440  C CB  . ASP A 1 616 ? 207.781 220.692 205.595 1.00 112.44 ? 648  ASP B CB  1 
ATOM   4441  C CG  . ASP A 1 616 ? 209.346 220.687 205.456 1.00 112.44 ? 648  ASP B CG  1 
ATOM   4442  O OD1 . ASP A 1 616 ? 209.874 219.705 204.955 1.00 112.44 ? 648  ASP B OD1 1 
ATOM   4443  O OD2 . ASP A 1 616 ? 209.976 221.625 205.876 1.00 112.44 ? 648  ASP B OD2 1 
ATOM   4444  N N   . LEU A 1 617 ? 208.166 217.755 205.100 1.00 87.94  ? 649  LEU B N   1 
ATOM   4445  C CA  . LEU A 1 617 ? 208.175 216.390 205.582 1.00 87.94  ? 649  LEU B CA  1 
ATOM   4446  C C   . LEU A 1 617 ? 208.148 216.411 207.086 1.00 87.94  ? 649  LEU B C   1 
ATOM   4447  O O   . LEU A 1 617 ? 207.574 215.521 207.716 1.00 87.94  ? 649  LEU B O   1 
ATOM   4448  C CB  . LEU A 1 617 ? 209.400 215.639 205.073 1.00 124.99 ? 649  LEU B CB  1 
ATOM   4449  C CG  . LEU A 1 617 ? 209.491 215.438 203.545 1.00 124.99 ? 649  LEU B CG  1 
ATOM   4450  C CD1 . LEU A 1 617 ? 210.821 214.775 203.218 1.00 124.99 ? 649  LEU B CD1 1 
ATOM   4451  C CD2 . LEU A 1 617 ? 208.325 214.576 203.049 1.00 124.99 ? 649  LEU B CD2 1 
ATOM   4452  N N   . GLY A 1 618 ? 208.756 217.444 207.671 1.00 88.85  ? 650  GLY B N   1 
ATOM   4453  C CA  . GLY A 1 618 ? 208.765 217.566 209.115 1.00 88.85  ? 650  GLY B CA  1 
ATOM   4454  C C   . GLY A 1 618 ? 207.331 217.765 209.562 1.00 88.85  ? 650  GLY B C   1 
ATOM   4455  O O   . GLY A 1 618 ? 206.891 217.189 210.563 1.00 88.85  ? 650  GLY B O   1 
ATOM   4456  N N   . THR A 1 619 ? 206.591 218.542 208.759 1.00 90.54  ? 651  THR B N   1 
ATOM   4457  C CA  . THR A 1 619 ? 205.193 218.835 209.026 1.00 90.54  ? 651  THR B CA  1 
ATOM   4458  C C   . THR A 1 619 ? 204.366 217.545 208.994 1.00 90.54  ? 651  THR B C   1 
ATOM   4459  O O   . THR A 1 619 ? 203.586 217.328 209.922 1.00 90.54  ? 651  THR B O   1 
ATOM   4460  C CB  . THR A 1 619 ? 204.592 219.871 208.009 1.00 123.94 ? 651  THR B CB  1 
ATOM   4461  O OG1 . THR A 1 619 ? 205.299 221.138 208.075 1.00 123.94 ? 651  THR B OG1 1 
ATOM   4462  C CG2 . THR A 1 619 ? 203.109 220.126 208.344 1.00 123.94 ? 651  THR B CG2 1 
ATOM   4463  N N   . CYS A 1 620 ? 204.563 216.660 207.965 1.00 90.67  ? 652  CYS B N   1 
ATOM   4464  C CA  . CYS A 1 620 ? 203.831 215.402 207.825 1.00 90.67  ? 652  CYS B CA  1 
ATOM   4465  C C   . CYS A 1 620 ? 204.094 214.453 208.981 1.00 90.67  ? 652  CYS B C   1 
ATOM   4466  O O   . CYS A 1 620 ? 203.156 213.844 209.517 1.00 90.67  ? 652  CYS B O   1 
ATOM   4467  C CB  . CYS A 1 620 ? 204.245 214.678 206.522 1.00 117.49 ? 652  CYS B CB  1 
ATOM   4468  S SG  . CYS A 1 620 ? 203.644 215.398 205.021 1.00 117.49 ? 652  CYS B SG  1 
ATOM   4469  N N   . SER A 1 621 ? 205.342 214.308 209.376 1.00 90.34  ? 653  SER B N   1 
ATOM   4470  C CA  . SER A 1 621 ? 205.596 213.351 210.424 1.00 90.34  ? 653  SER B CA  1 
ATOM   4471  C C   . SER A 1 621 ? 205.056 213.810 211.749 1.00 90.34  ? 653  SER B C   1 
ATOM   4472  O O   . SER A 1 621 ? 204.470 213.013 212.498 1.00 90.34  ? 653  SER B O   1 
ATOM   4473  C CB  . SER A 1 621 ? 207.071 213.053 210.509 1.00 120.33 ? 653  SER B CB  1 
ATOM   4474  O OG  . SER A 1 621 ? 207.501 212.382 209.347 1.00 120.33 ? 653  SER B OG  1 
ATOM   4475  N N   . LEU A 1 622 ? 205.204 215.090 212.046 1.00 91.52  ? 654  LEU B N   1 
ATOM   4476  C CA  . LEU A 1 622 ? 204.693 215.553 213.300 1.00 91.52  ? 654  LEU B CA  1 
ATOM   4477  C C   . LEU A 1 622 ? 203.195 215.613 213.244 1.00 91.52  ? 654  LEU B C   1 
ATOM   4478  O O   . LEU A 1 622 ? 202.525 215.339 214.238 1.00 91.52  ? 654  LEU B O   1 
ATOM   4479  C CB  . LEU A 1 622 ? 205.298 216.897 213.647 1.00 130.08 ? 654  LEU B CB  1 
ATOM   4480  C CG  . LEU A 1 622 ? 206.811 216.876 213.976 1.00 130.08 ? 654  LEU B CG  1 
ATOM   4481  C CD1 . LEU A 1 622 ? 207.296 218.305 214.081 1.00 130.08 ? 654  LEU B CD1 1 
ATOM   4482  C CD2 . LEU A 1 622 ? 207.070 216.117 215.318 1.00 130.08 ? 654  LEU B CD2 1 
ATOM   4483  N N   . ARG A 1 623 ? 202.639 215.946 212.090 1.00 90.11  ? 655  ARG B N   1 
ATOM   4484  C CA  . ARG A 1 623 ? 201.216 216.013 212.012 1.00 90.11  ? 655  ARG B CA  1 
ATOM   4485  C C   . ARG A 1 623 ? 200.640 214.653 212.275 1.00 90.11  ? 655  ARG B C   1 
ATOM   4486  O O   . ARG A 1 623 ? 199.743 214.530 213.094 1.00 90.11  ? 655  ARG B O   1 
ATOM   4487  C CB  . ARG A 1 623 ? 200.768 216.549 210.662 1.00 126.55 ? 655  ARG B CB  1 
ATOM   4488  C CG  . ARG A 1 623 ? 199.271 216.663 210.460 1.00 126.55 ? 655  ARG B CG  1 
ATOM   4489  C CD  . ARG A 1 623 ? 198.950 217.422 209.228 1.00 126.55 ? 655  ARG B CD  1 
ATOM   4490  N NE  . ARG A 1 623 ? 197.517 217.431 208.948 1.00 126.55 ? 655  ARG B NE  1 
ATOM   4491  C CZ  . ARG A 1 623 ? 196.927 218.147 207.967 1.00 126.55 ? 655  ARG B CZ  1 
ATOM   4492  N NH1 . ARG A 1 623 ? 195.625 218.061 207.776 1.00 126.55 ? 655  ARG B NH1 1 
ATOM   4493  N NH2 . ARG A 1 623 ? 197.643 218.932 207.193 1.00 126.55 ? 655  ARG B NH2 1 
ATOM   4494  N N   . ARG A 1 624 ? 201.161 213.604 211.657 1.00 88.14  ? 656  ARG B N   1 
ATOM   4495  C CA  . ARG A 1 624 ? 200.518 212.329 211.874 1.00 88.14  ? 656  ARG B CA  1 
ATOM   4496  C C   . ARG A 1 624 ? 200.647 211.836 213.303 1.00 88.14  ? 656  ARG B C   1 
ATOM   4497  O O   . ARG A 1 624 ? 199.668 211.338 213.880 1.00 88.14  ? 656  ARG B O   1 
ATOM   4498  C CB  . ARG A 1 624 ? 201.097 211.268 210.982 1.00 123.79 ? 656  ARG B CB  1 
ATOM   4499  C CG  . ARG A 1 624 ? 200.805 211.371 209.510 1.00 123.79 ? 656  ARG B CG  1 
ATOM   4500  C CD  . ARG A 1 624 ? 201.434 210.235 208.871 1.00 123.79 ? 656  ARG B CD  1 
ATOM   4501  N NE  . ARG A 1 624 ? 201.408 210.238 207.435 1.00 123.79 ? 656  ARG B NE  1 
ATOM   4502  C CZ  . ARG A 1 624 ? 201.700 209.145 206.704 1.00 123.79 ? 656  ARG B CZ  1 
ATOM   4503  N NH1 . ARG A 1 624 ? 201.733 209.161 205.394 1.00 123.79 ? 656  ARG B NH1 1 
ATOM   4504  N NH2 . ARG A 1 624 ? 201.955 208.010 207.291 1.00 123.79 ? 656  ARG B NH2 1 
ATOM   4505  N N   . ILE A 1 625 ? 201.808 212.047 213.933 1.00 89.87  ? 657  ILE B N   1 
ATOM   4506  C CA  . ILE A 1 625 ? 201.946 211.507 215.270 1.00 89.87  ? 657  ILE B CA  1 
ATOM   4507  C C   . ILE A 1 625 ? 201.018 212.275 216.194 1.00 89.87  ? 657  ILE B C   1 
ATOM   4508  O O   . ILE A 1 625 ? 200.406 211.688 217.093 1.00 89.87  ? 657  ILE B O   1 
ATOM   4509  C CB  . ILE A 1 625 ? 203.428 211.539 215.758 1.00 127.74 ? 657  ILE B CB  1 
ATOM   4510  C CG1 . ILE A 1 625 ? 203.681 210.587 216.964 1.00 127.74 ? 657  ILE B CG1 1 
ATOM   4511  C CG2 . ILE A 1 625 ? 203.836 212.894 216.200 1.00 127.74 ? 657  ILE B CG2 1 
ATOM   4512  C CD1 . ILE A 1 625 ? 203.545 209.099 216.662 1.00 127.74 ? 657  ILE B CD1 1 
ATOM   4513  N N   . PHE A 1 626 ? 200.848 213.570 215.938 1.00 90.87  ? 658  PHE B N   1 
ATOM   4514  C CA  . PHE A 1 626 ? 199.971 214.331 216.769 1.00 90.87  ? 658  PHE B CA  1 
ATOM   4515  C C   . PHE A 1 626 ? 198.518 214.338 216.344 1.00 90.87  ? 658  PHE B C   1 
ATOM   4516  O O   . PHE A 1 626 ? 197.665 214.631 217.173 1.00 90.87  ? 658  PHE B O   1 
ATOM   4517  C CB  . PHE A 1 626 ? 200.513 215.730 216.980 1.00 122.89 ? 658  PHE B CB  1 
ATOM   4518  C CG  . PHE A 1 626 ? 201.672 215.695 217.894 1.00 122.89 ? 658  PHE B CG  1 
ATOM   4519  C CD1 . PHE A 1 626 ? 201.459 215.469 219.247 1.00 122.89 ? 658  PHE B CD1 1 
ATOM   4520  C CD2 . PHE A 1 626 ? 202.965 215.849 217.444 1.00 122.89 ? 658  PHE B CD2 1 
ATOM   4521  C CE1 . PHE A 1 626 ? 202.508 215.388 220.117 1.00 122.89 ? 658  PHE B CE1 1 
ATOM   4522  C CE2 . PHE A 1 626 ? 204.020 215.769 218.318 1.00 122.89 ? 658  PHE B CE2 1 
ATOM   4523  C CZ  . PHE A 1 626 ? 203.791 215.535 219.654 1.00 122.89 ? 658  PHE B CZ  1 
ATOM   4524  N N   . LEU A 1 627 ? 198.162 213.920 215.122 1.00 85.72  ? 659  LEU B N   1 
ATOM   4525  C CA  . LEU A 1 627 ? 196.729 213.881 214.842 1.00 85.72  ? 659  LEU B CA  1 
ATOM   4526  C C   . LEU A 1 627 ? 196.179 212.841 215.795 1.00 85.72  ? 659  LEU B C   1 
ATOM   4527  O O   . LEU A 1 627 ? 195.100 212.987 216.368 1.00 85.72  ? 659  LEU B O   1 
ATOM   4528  C CB  . LEU A 1 627 ? 196.358 213.437 213.403 1.00 121.84 ? 659  LEU B CB  1 
ATOM   4529  C CG  . LEU A 1 627 ? 196.701 214.367 212.185 1.00 121.84 ? 659  LEU B CG  1 
ATOM   4530  C CD1 . LEU A 1 627 ? 196.282 213.650 210.888 1.00 121.84 ? 659  LEU B CD1 1 
ATOM   4531  C CD2 . LEU A 1 627 ? 196.059 215.720 212.346 1.00 121.84 ? 659  LEU B CD2 1 
ATOM   4532  N N   . GLY A 1 628 ? 196.971 211.792 215.998 1.00 88.17  ? 660  GLY B N   1 
ATOM   4533  C CA  . GLY A 1 628 ? 196.629 210.755 216.944 1.00 88.17  ? 660  GLY B CA  1 
ATOM   4534  C C   . GLY A 1 628 ? 196.724 211.291 218.377 1.00 88.17  ? 660  GLY B C   1 
ATOM   4535  O O   . GLY A 1 628 ? 195.714 211.368 219.086 1.00 88.17  ? 660  GLY B O   1 
ATOM   4536  N N   . LEU A 1 629 ? 197.917 211.715 218.801 1.00 92.38  ? 661  LEU B N   1 
ATOM   4537  C CA  . LEU A 1 629 ? 198.123 212.080 220.199 1.00 92.38  ? 661  LEU B CA  1 
ATOM   4538  C C   . LEU A 1 629 ? 197.283 213.245 220.679 1.00 92.38  ? 661  LEU B C   1 
ATOM   4539  O O   . LEU A 1 629 ? 196.772 213.231 221.805 1.00 92.38  ? 661  LEU B O   1 
ATOM   4540  C CB  . LEU A 1 629 ? 199.591 212.411 220.425 1.00 131.30 ? 661  LEU B CB  1 
ATOM   4541  C CG  . LEU A 1 629 ? 200.571 211.261 220.314 1.00 131.30 ? 661  LEU B CG  1 
ATOM   4542  C CD1 . LEU A 1 629 ? 201.969 211.835 220.351 1.00 131.30 ? 661  LEU B CD1 1 
ATOM   4543  C CD2 . LEU A 1 629 ? 200.351 210.269 221.442 1.00 131.30 ? 661  LEU B CD2 1 
ATOM   4544  N N   . GLY A 1 630 ? 197.023 214.212 219.810 1.00 92.64  ? 662  GLY B N   1 
ATOM   4545  C CA  . GLY A 1 630 ? 196.254 215.395 220.145 1.00 92.64  ? 662  GLY B CA  1 
ATOM   4546  C C   . GLY A 1 630 ? 194.814 215.037 220.499 1.00 92.64  ? 662  GLY B C   1 
ATOM   4547  O O   . GLY A 1 630 ? 194.080 215.865 221.023 1.00 92.64  ? 662  GLY B O   1 
ATOM   4548  N N   . MET A 1 631 ? 194.384 213.827 220.173 1.00 92.63  ? 663  MET B N   1 
ATOM   4549  C CA  . MET A 1 631 ? 193.063 213.366 220.509 1.00 92.63  ? 663  MET B CA  1 
ATOM   4550  C C   . MET A 1 631 ? 193.133 212.309 221.640 1.00 92.63  ? 663  MET B C   1 
ATOM   4551  O O   . MET A 1 631 ? 192.367 212.361 222.614 1.00 92.63  ? 663  MET B O   1 
ATOM   4552  C CB  . MET A 1 631 ? 192.392 212.823 219.247 1.00 128.87 ? 663  MET B CB  1 
ATOM   4553  C CG  . MET A 1 631 ? 190.962 212.438 219.436 1.00 128.87 ? 663  MET B CG  1 
ATOM   4554  S SD  . MET A 1 631 ? 190.164 211.811 217.962 1.00 128.87 ? 663  MET B SD  1 
ATOM   4555  C CE  . MET A 1 631 ? 188.696 211.119 218.737 1.00 128.87 ? 663  MET B CE  1 
ATOM   4556  N N   . SER A 1 632 ? 194.042 211.340 221.483 1.00 94.23  ? 664  SER B N   1 
ATOM   4557  C CA  . SER A 1 632 ? 194.144 210.206 222.391 1.00 94.23  ? 664  SER B CA  1 
ATOM   4558  C C   . SER A 1 632 ? 194.731 210.468 223.743 1.00 94.23  ? 664  SER B C   1 
ATOM   4559  O O   . SER A 1 632 ? 194.424 209.732 224.676 1.00 94.23  ? 664  SER B O   1 
ATOM   4560  C CB  . SER A 1 632 ? 195.019 209.151 221.803 1.00 125.51 ? 664  SER B CB  1 
ATOM   4561  O OG  . SER A 1 632 ? 196.316 209.609 221.724 1.00 125.51 ? 664  SER B OG  1 
ATOM   4562  N N   . ILE A 1 633 ? 195.560 211.489 223.903 1.00 95.58  ? 665  ILE B N   1 
ATOM   4563  C CA  . ILE A 1 633 ? 196.120 211.689 225.226 1.00 95.58  ? 665  ILE B CA  1 
ATOM   4564  C C   . ILE A 1 633 ? 195.012 212.058 226.169 1.00 95.58  ? 665  ILE B C   1 
ATOM   4565  O O   . ILE A 1 633 ? 194.950 211.546 227.289 1.00 95.58  ? 665  ILE B O   1 
ATOM   4566  C CB  . ILE A 1 633 ? 197.236 212.742 225.266 1.00 135.85 ? 665  ILE B CB  1 
ATOM   4567  C CG1 . ILE A 1 633 ? 198.465 212.193 224.492 1.00 135.85 ? 665  ILE B CG1 1 
ATOM   4568  C CG2 . ILE A 1 633 ? 197.591 213.090 226.768 1.00 135.85 ? 665  ILE B CG2 1 
ATOM   4569  C CD1 . ILE A 1 633 ? 199.530 213.219 224.201 1.00 135.85 ? 665  ILE B CD1 1 
ATOM   4570  N N   . SER A 1 634 ? 194.132 212.950 225.723 1.00 94.82  ? 666  SER B N   1 
ATOM   4571  C CA  . SER A 1 634 ? 193.038 213.378 226.555 1.00 94.82  ? 666  SER B CA  1 
ATOM   4572  C C   . SER A 1 634 ? 192.155 212.218 226.911 1.00 94.82  ? 666  SER B C   1 
ATOM   4573  O O   . SER A 1 634 ? 191.767 212.070 228.071 1.00 94.82  ? 666  SER B O   1 
ATOM   4574  C CB  . SER A 1 634 ? 192.209 214.404 225.818 1.00 126.30 ? 666  SER B CB  1 
ATOM   4575  O OG  . SER A 1 634 ? 192.938 215.576 225.608 1.00 126.30 ? 666  SER B OG  1 
ATOM   4576  N N   . TYR A 1 635 ? 191.886 211.331 225.973 1.00 95.27  ? 667  TYR B N   1 
ATOM   4577  C CA  . TYR A 1 635 ? 191.011 210.272 226.388 1.00 95.27  ? 667  TYR B CA  1 
ATOM   4578  C C   . TYR A 1 635 ? 191.724 209.281 227.259 1.00 95.27  ? 667  TYR B C   1 
ATOM   4579  O O   . TYR A 1 635 ? 191.158 208.811 228.241 1.00 95.27  ? 667  TYR B O   1 
ATOM   4580  C CB  . TYR A 1 635 ? 190.403 209.606 225.197 1.00 127.88 ? 667  TYR B CB  1 
ATOM   4581  C CG  . TYR A 1 635 ? 189.589 210.537 224.503 1.00 127.88 ? 667  TYR B CG  1 
ATOM   4582  C CD1 . TYR A 1 635 ? 188.528 211.137 225.138 1.00 127.88 ? 667  TYR B CD1 1 
ATOM   4583  C CD2 . TYR A 1 635 ? 189.913 210.868 223.236 1.00 127.88 ? 667  TYR B CD2 1 
ATOM   4584  C CE1 . TYR A 1 635 ? 187.814 212.060 224.498 1.00 127.88 ? 667  TYR B CE1 1 
ATOM   4585  C CE2 . TYR A 1 635 ? 189.181 211.794 222.599 1.00 127.88 ? 667  TYR B CE2 1 
ATOM   4586  C CZ  . TYR A 1 635 ? 188.150 212.389 223.213 1.00 127.88 ? 667  TYR B CZ  1 
ATOM   4587  O OH  . TYR A 1 635 ? 187.443 213.320 222.528 1.00 127.88 ? 667  TYR B OH  1 
ATOM   4588  N N   . ALA A 1 636 ? 192.991 208.996 226.989 1.00 96.10  ? 668  ALA B N   1 
ATOM   4589  C CA  . ALA A 1 636 ? 193.658 208.021 227.826 1.00 96.10  ? 668  ALA B CA  1 
ATOM   4590  C C   . ALA A 1 636 ? 193.674 208.498 229.266 1.00 96.10  ? 668  ALA B C   1 
ATOM   4591  O O   . ALA A 1 636 ? 193.438 207.719 230.198 1.00 96.10  ? 668  ALA B O   1 
ATOM   4592  C CB  . ALA A 1 636 ? 195.081 207.799 227.341 1.00 129.83 ? 668  ALA B CB  1 
ATOM   4593  N N   . ALA A 1 637 ? 193.914 209.794 229.456 1.00 94.98  ? 669  ALA B N   1 
ATOM   4594  C CA  . ALA A 1 637 ? 193.944 210.347 230.785 1.00 94.98  ? 669  ALA B CA  1 
ATOM   4595  C C   . ALA A 1 637 ? 192.557 210.316 231.432 1.00 94.98  ? 669  ALA B C   1 
ATOM   4596  O O   . ALA A 1 637 ? 192.424 209.976 232.619 1.00 94.98  ? 669  ALA B O   1 
ATOM   4597  C CB  . ALA A 1 637 ? 194.501 211.743 230.699 1.00 128.31 ? 669  ALA B CB  1 
ATOM   4598  N N   . LEU A 1 638 ? 191.508 210.596 230.651 1.00 93.70  ? 670  LEU B N   1 
ATOM   4599  C CA  . LEU A 1 638 ? 190.168 210.550 231.194 1.00 93.70  ? 670  LEU B CA  1 
ATOM   4600  C C   . LEU A 1 638 ? 189.797 209.157 231.592 1.00 93.70  ? 670  LEU B C   1 
ATOM   4601  O O   . LEU A 1 638 ? 189.126 208.967 232.609 1.00 93.70  ? 670  LEU B O   1 
ATOM   4602  C CB  . LEU A 1 638 ? 189.148 211.061 230.188 1.00 133.18 ? 670  LEU B CB  1 
ATOM   4603  C CG  . LEU A 1 638 ? 189.140 212.548 229.903 1.00 133.18 ? 670  LEU B CG  1 
ATOM   4604  C CD1 . LEU A 1 638 ? 188.257 212.795 228.702 1.00 133.18 ? 670  LEU B CD1 1 
ATOM   4605  C CD2 . LEU A 1 638 ? 188.590 213.319 231.125 1.00 133.18 ? 670  LEU B CD2 1 
ATOM   4606  N N   . LEU A 1 639 ? 190.225 208.170 230.822 1.00 94.41  ? 671  LEU B N   1 
ATOM   4607  C CA  . LEU A 1 639 ? 189.887 206.814 231.161 1.00 94.41  ? 671  LEU B CA  1 
ATOM   4608  C C   . LEU A 1 639 ? 190.511 206.410 232.453 1.00 94.41  ? 671  LEU B C   1 
ATOM   4609  O O   . LEU A 1 639 ? 189.848 205.819 233.303 1.00 94.41  ? 671  LEU B O   1 
ATOM   4610  C CB  . LEU A 1 639 ? 190.433 205.849 230.108 1.00 134.19 ? 671  LEU B CB  1 
ATOM   4611  C CG  . LEU A 1 639 ? 189.802 205.892 228.775 1.00 134.19 ? 671  LEU B CG  1 
ATOM   4612  C CD1 . LEU A 1 639 ? 190.564 205.082 227.817 1.00 134.19 ? 671  LEU B CD1 1 
ATOM   4613  C CD2 . LEU A 1 639 ? 188.482 205.379 228.854 1.00 134.19 ? 671  LEU B CD2 1 
ATOM   4614  N N   . THR A 1 640 ? 191.767 206.777 232.657 1.00 93.28  ? 672  THR B N   1 
ATOM   4615  C CA  . THR A 1 640 ? 192.421 206.366 233.870 1.00 93.28  ? 672  THR B CA  1 
ATOM   4616  C C   . THR A 1 640 ? 191.720 206.956 235.065 1.00 93.28  ? 672  THR B C   1 
ATOM   4617  O O   . THR A 1 640 ? 191.400 206.246 236.018 1.00 93.28  ? 672  THR B O   1 
ATOM   4618  C CB  . THR A 1 640 ? 193.888 206.814 233.861 1.00 127.69 ? 672  THR B CB  1 
ATOM   4619  O OG1 . THR A 1 640 ? 194.565 206.198 232.760 1.00 127.69 ? 672  THR B OG1 1 
ATOM   4620  C CG2 . THR A 1 640 ? 194.574 206.408 235.142 1.00 127.69 ? 672  THR B CG2 1 
ATOM   4621  N N   . LYS A 1 641 ? 191.429 208.249 235.009 1.00 89.87  ? 673  LYS B N   1 
ATOM   4622  C CA  . LYS A 1 641 ? 190.822 208.881 236.158 1.00 89.87  ? 673  LYS B CA  1 
ATOM   4623  C C   . LYS A 1 641 ? 189.392 208.434 236.374 1.00 89.87  ? 673  LYS B C   1 
ATOM   4624  O O   . LYS A 1 641 ? 188.963 208.221 237.516 1.00 89.87  ? 673  LYS B O   1 
ATOM   4625  C CB  . LYS A 1 641 ? 190.900 210.392 236.031 1.00 128.55 ? 673  LYS B CB  1 
ATOM   4626  C CG  . LYS A 1 641 ? 190.333 211.136 237.223 1.00 128.55 ? 673  LYS B CG  1 
ATOM   4627  C CD  . LYS A 1 641 ? 190.634 212.625 237.134 1.00 128.55 ? 673  LYS B CD  1 
ATOM   4628  C CE  . LYS A 1 641 ? 189.931 213.392 238.234 1.00 128.55 ? 673  LYS B CE  1 
ATOM   4629  N NZ  . LYS A 1 641 ? 190.466 213.106 239.597 1.00 128.55 ? 673  LYS B NZ  1 
ATOM   4630  N N   . THR A 1 642 ? 188.635 208.311 235.294 1.00 90.05  ? 674  THR B N   1 
ATOM   4631  C CA  . THR A 1 642 ? 187.242 207.964 235.404 1.00 90.05  ? 674  THR B CA  1 
ATOM   4632  C C   . THR A 1 642 ? 187.143 206.561 235.956 1.00 90.05  ? 674  THR B C   1 
ATOM   4633  O O   . THR A 1 642 ? 186.270 206.271 236.782 1.00 90.05  ? 674  THR B O   1 
ATOM   4634  C CB  . THR A 1 642 ? 186.525 208.046 234.056 1.00 123.27 ? 674  THR B CB  1 
ATOM   4635  O OG1 . THR A 1 642 ? 186.673 209.353 233.521 1.00 123.27 ? 674  THR B OG1 1 
ATOM   4636  C CG2 . THR A 1 642 ? 185.032 207.819 234.296 1.00 123.27 ? 674  THR B CG2 1 
ATOM   4637  N N   . ASN A 1 643 ? 188.020 205.673 235.482 1.00 88.99  ? 675  ASN B N   1 
ATOM   4638  C CA  . ASN A 1 643 ? 188.015 204.313 235.942 1.00 88.99  ? 675  ASN B CA  1 
ATOM   4639  C C   . ASN A 1 643 ? 188.368 204.283 237.417 1.00 88.99  ? 675  ASN B C   1 
ATOM   4640  O O   . ASN A 1 643 ? 187.706 203.592 238.186 1.00 88.99  ? 675  ASN B O   1 
ATOM   4641  C CB  . ASN A 1 643 ? 188.987 203.493 235.131 1.00 118.37 ? 675  ASN B CB  1 
ATOM   4642  C CG  . ASN A 1 643 ? 188.895 202.022 235.349 1.00 118.37 ? 675  ASN B CG  1 
ATOM   4643  O OD1 . ASN A 1 643 ? 187.818 201.424 235.236 1.00 118.37 ? 675  ASN B OD1 1 
ATOM   4644  N ND2 . ASN A 1 643 ? 190.013 201.407 235.638 1.00 118.37 ? 675  ASN B ND2 1 
ATOM   4645  N N   . ARG A 1 644 ? 189.326 205.111 237.874 1.00 87.11  ? 676  ARG B N   1 
ATOM   4646  C CA  . ARG A 1 644 ? 189.629 205.079 239.299 1.00 87.11  ? 676  ARG B CA  1 
ATOM   4647  C C   . ARG A 1 644 ? 188.386 205.400 240.105 1.00 87.11  ? 676  ARG B C   1 
ATOM   4648  O O   . ARG A 1 644 ? 188.083 204.713 241.081 1.00 87.11  ? 676  ARG B O   1 
ATOM   4649  C CB  . ARG A 1 644 ? 190.672 206.107 239.698 1.00 122.34 ? 676  ARG B CB  1 
ATOM   4650  C CG  . ARG A 1 644 ? 192.065 205.869 239.232 1.00 122.34 ? 676  ARG B CG  1 
ATOM   4651  C CD  . ARG A 1 644 ? 192.990 206.898 239.734 1.00 122.34 ? 676  ARG B CD  1 
ATOM   4652  N NE  . ARG A 1 644 ? 193.427 206.620 241.102 1.00 122.34 ? 676  ARG B NE  1 
ATOM   4653  C CZ  . ARG A 1 644 ? 193.005 207.205 242.235 1.00 122.34 ? 676  ARG B CZ  1 
ATOM   4654  N NH1 . ARG A 1 644 ? 193.581 206.796 243.338 1.00 122.34 ? 676  ARG B NH1 1 
ATOM   4655  N NH2 . ARG A 1 644 ? 192.067 208.138 242.255 1.00 122.34 ? 676  ARG B NH2 1 
ATOM   4656  N N   . ILE A 1 645 ? 187.610 206.382 239.650 1.00 84.42  ? 677  ILE B N   1 
ATOM   4657  C CA  . ILE A 1 645 ? 186.398 206.748 240.362 1.00 84.42  ? 677  ILE B CA  1 
ATOM   4658  C C   . ILE A 1 645 ? 185.406 205.608 240.376 1.00 84.42  ? 677  ILE B C   1 
ATOM   4659  O O   . ILE A 1 645 ? 184.843 205.275 241.425 1.00 84.42  ? 677  ILE B O   1 
ATOM   4660  C CB  . ILE A 1 645 ? 185.729 207.983 239.712 1.00 119.99 ? 677  ILE B CB  1 
ATOM   4661  C CG1 . ILE A 1 645 ? 186.622 209.241 239.938 1.00 119.99 ? 677  ILE B CG1 1 
ATOM   4662  C CG2 . ILE A 1 645 ? 184.289 208.171 240.228 1.00 119.99 ? 677  ILE B CG2 1 
ATOM   4663  C CD1 . ILE A 1 645 ? 186.232 210.481 239.108 1.00 119.99 ? 677  ILE B CD1 1 
ATOM   4664  N N   . TYR A 1 646 ? 185.196 204.993 239.226 1.00 85.17  ? 678  TYR B N   1 
ATOM   4665  C CA  . TYR A 1 646 ? 184.251 203.912 239.156 1.00 85.17  ? 678  TYR B CA  1 
ATOM   4666  C C   . TYR A 1 646 ? 184.649 202.745 240.036 1.00 85.17  ? 678  TYR B C   1 
ATOM   4667  O O   . TYR A 1 646 ? 183.803 202.187 240.742 1.00 85.17  ? 678  TYR B O   1 
ATOM   4668  C CB  . TYR A 1 646 ? 184.062 203.443 237.738 1.00 114.32 ? 678  TYR B CB  1 
ATOM   4669  C CG  . TYR A 1 646 ? 183.055 202.393 237.681 1.00 114.32 ? 678  TYR B CG  1 
ATOM   4670  C CD1 . TYR A 1 646 ? 181.740 202.696 237.983 1.00 114.32 ? 678  TYR B CD1 1 
ATOM   4671  C CD2 . TYR A 1 646 ? 183.415 201.127 237.320 1.00 114.32 ? 678  TYR B CD2 1 
ATOM   4672  C CE1 . TYR A 1 646 ? 180.803 201.721 237.936 1.00 114.32 ? 678  TYR B CE1 1 
ATOM   4673  C CE2 . TYR A 1 646 ? 182.467 200.151 237.254 1.00 114.32 ? 678  TYR B CE2 1 
ATOM   4674  C CZ  . TYR A 1 646 ? 181.164 200.443 237.556 1.00 114.32 ? 678  TYR B CZ  1 
ATOM   4675  O OH  . TYR A 1 646 ? 180.206 199.460 237.481 1.00 114.32 ? 678  TYR B OH  1 
ATOM   4676  N N   . ARG A 1 647 ? 185.925 202.356 239.989 1.00 84.86  ? 679  ARG B N   1 
ATOM   4677  C CA  . ARG A 1 647 ? 186.395 201.232 240.771 1.00 84.86  ? 679  ARG B CA  1 
ATOM   4678  C C   . ARG A 1 647 ? 186.255 201.491 242.256 1.00 84.86  ? 679  ARG B C   1 
ATOM   4679  O O   . ARG A 1 647 ? 185.871 200.586 242.991 1.00 84.86  ? 679  ARG B O   1 
ATOM   4680  C CB  . ARG A 1 647 ? 187.850 200.910 240.476 1.00 119.18 ? 679  ARG B CB  1 
ATOM   4681  C CG  . ARG A 1 647 ? 188.128 200.307 239.102 1.00 119.18 ? 679  ARG B CG  1 
ATOM   4682  C CD  . ARG A 1 647 ? 189.561 199.971 238.944 1.00 119.18 ? 679  ARG B CD  1 
ATOM   4683  N NE  . ARG A 1 647 ? 189.939 198.851 239.808 1.00 119.18 ? 679  ARG B NE  1 
ATOM   4684  C CZ  . ARG A 1 647 ? 191.194 198.546 240.222 1.00 119.18 ? 679  ARG B CZ  1 
ATOM   4685  N NH1 . ARG A 1 647 ? 191.397 197.514 241.005 1.00 119.18 ? 679  ARG B NH1 1 
ATOM   4686  N NH2 . ARG A 1 647 ? 192.239 199.250 239.878 1.00 119.18 ? 679  ARG B NH2 1 
ATOM   4687  N N   . ILE A 1 648 ? 186.526 202.712 242.709 1.00 82.20  ? 680  ILE B N   1 
ATOM   4688  C CA  . ILE A 1 648 ? 186.401 203.021 244.128 1.00 82.20  ? 680  ILE B CA  1 
ATOM   4689  C C   . ILE A 1 648 ? 184.953 202.898 244.531 1.00 82.20  ? 680  ILE B C   1 
ATOM   4690  O O   . ILE A 1 648 ? 184.626 202.345 245.587 1.00 82.20  ? 680  ILE B O   1 
ATOM   4691  C CB  . ILE A 1 648 ? 186.894 204.435 244.435 1.00 116.83 ? 680  ILE B CB  1 
ATOM   4692  C CG1 . ILE A 1 648 ? 188.374 204.491 244.210 1.00 116.83 ? 680  ILE B CG1 1 
ATOM   4693  C CG2 . ILE A 1 648 ? 186.551 204.800 245.898 1.00 116.83 ? 680  ILE B CG2 1 
ATOM   4694  C CD1 . ILE A 1 648 ? 188.972 205.895 244.133 1.00 116.83 ? 680  ILE B CD1 1 
ATOM   4695  N N   . PHE A 1 649 ? 184.078 203.460 243.700 1.00 78.96  ? 681  PHE B N   1 
ATOM   4696  C CA  . PHE A 1 649 ? 182.661 203.437 243.943 1.00 78.96  ? 681  PHE B CA  1 
ATOM   4697  C C   . PHE A 1 649 ? 182.102 202.026 244.064 1.00 78.96  ? 681  PHE B C   1 
ATOM   4698  O O   . PHE A 1 649 ? 181.402 201.724 245.039 1.00 78.96  ? 681  PHE B O   1 
ATOM   4699  C CB  . PHE A 1 649 ? 181.981 204.205 242.824 1.00 106.78 ? 681  PHE B CB  1 
ATOM   4700  C CG  . PHE A 1 649 ? 180.538 204.095 242.788 1.00 106.78 ? 681  PHE B CG  1 
ATOM   4701  C CD1 . PHE A 1 649 ? 179.742 204.718 243.713 1.00 106.78 ? 681  PHE B CD1 1 
ATOM   4702  C CD2 . PHE A 1 649 ? 179.950 203.379 241.768 1.00 106.78 ? 681  PHE B CD2 1 
ATOM   4703  C CE1 . PHE A 1 649 ? 178.383 204.606 243.628 1.00 106.78 ? 681  PHE B CE1 1 
ATOM   4704  C CE2 . PHE A 1 649 ? 178.603 203.279 241.682 1.00 106.78 ? 681  PHE B CE2 1 
ATOM   4705  C CZ  . PHE A 1 649 ? 177.816 203.890 242.616 1.00 106.78 ? 681  PHE B CZ  1 
ATOM   4706  N N   . GLU A 1 650 ? 182.431 201.150 243.119 1.00 78.79  ? 682  GLU B N   1 
ATOM   4707  C CA  . GLU A 1 650 ? 181.937 199.785 243.192 1.00 78.79  ? 682  GLU B CA  1 
ATOM   4708  C C   . GLU A 1 650 ? 182.647 198.963 244.260 1.00 78.79  ? 682  GLU B C   1 
ATOM   4709  O O   . GLU A 1 650 ? 182.031 198.121 244.912 1.00 78.79  ? 682  GLU B O   1 
ATOM   4710  C CB  . GLU A 1 650 ? 182.099 199.077 241.856 1.00 103.84 ? 682  GLU B CB  1 
ATOM   4711  C CG  . GLU A 1 650 ? 181.236 199.585 240.761 1.00 103.84 ? 682  GLU B CG  1 
ATOM   4712  C CD  . GLU A 1 650 ? 179.731 199.430 240.973 1.00 103.84 ? 682  GLU B CD  1 
ATOM   4713  O OE1 . GLU A 1 650 ? 179.283 198.375 241.373 1.00 103.84 ? 682  GLU B OE1 1 
ATOM   4714  O OE2 . GLU A 1 650 ? 179.015 200.368 240.727 1.00 103.84 ? 682  GLU B OE2 1 
ATOM   4715  N N   . GLN A 1 651 ? 183.935 199.213 244.489 1.00 77.25  ? 683  GLN B N   1 
ATOM   4716  C CA  . GLN A 1 651 ? 184.686 198.443 245.461 1.00 77.25  ? 683  GLN B CA  1 
ATOM   4717  C C   . GLN A 1 651 ? 184.127 198.644 246.838 1.00 77.25  ? 683  GLN B C   1 
ATOM   4718  O O   . GLN A 1 651 ? 183.945 197.668 247.567 1.00 77.25  ? 683  GLN B O   1 
ATOM   4719  C CB  . GLN A 1 651 ? 186.146 198.874 245.432 1.00 105.00 ? 683  GLN B CB  1 
ATOM   4720  C CG  . GLN A 1 651 ? 187.099 198.187 246.377 1.00 105.00 ? 683  GLN B CG  1 
ATOM   4721  C CD  . GLN A 1 651 ? 187.305 196.761 246.130 1.00 105.00 ? 683  GLN B CD  1 
ATOM   4722  O OE1 . GLN A 1 651 ? 186.815 196.169 245.151 1.00 105.00 ? 683  GLN B OE1 1 
ATOM   4723  N NE2 . GLN A 1 651 ? 188.077 196.184 247.018 1.00 105.00 ? 683  GLN B NE2 1 
ATOM   4724  N N   . GLY A 1 652 ? 183.698 199.867 247.132 1.00 72.62  ? 684  GLY B N   1 
ATOM   4725  C CA  . GLY A 1 652 ? 183.149 200.221 248.427 1.00 72.62  ? 684  GLY B CA  1 
ATOM   4726  C C   . GLY A 1 652 ? 181.844 199.495 248.752 1.00 72.62  ? 684  GLY B C   1 
ATOM   4727  O O   . GLY A 1 652 ? 181.394 199.513 249.898 1.00 72.62  ? 684  GLY B O   1 
ATOM   4728  N N   . LYS A 1 653 ? 181.223 198.854 247.759 1.00 72.66  ? 685  LYS B N   1 
ATOM   4729  C CA  . LYS A 1 653 ? 179.997 198.129 248.001 1.00 72.66  ? 685  LYS B CA  1 
ATOM   4730  C C   . LYS A 1 653 ? 180.304 196.752 248.580 1.00 72.66  ? 685  LYS B C   1 
ATOM   4731  O O   . LYS A 1 653 ? 179.419 196.108 249.147 1.00 72.66  ? 685  LYS B O   1 
ATOM   4732  C CB  . LYS A 1 653 ? 179.228 197.918 246.707 1.00 103.93 ? 685  LYS B CB  1 
ATOM   4733  C CG  . LYS A 1 653 ? 178.684 199.154 246.036 1.00 103.93 ? 685  LYS B CG  1 
ATOM   4734  C CD  . LYS A 1 653 ? 177.994 198.724 244.770 1.00 103.93 ? 685  LYS B CD  1 
ATOM   4735  C CE  . LYS A 1 653 ? 177.459 199.857 243.936 1.00 103.93 ? 685  LYS B CE  1 
ATOM   4736  N NZ  . LYS A 1 653 ? 176.837 199.301 242.692 1.00 103.93 ? 685  LYS B NZ  1 
ATOM   4737  N N   . ARG A 1 654 ? 181.535 196.256 248.362 1.00 75.36  ? 686  ARG B N   1 
ATOM   4738  C CA  . ARG A 1 654 ? 181.907 194.922 248.820 1.00 75.36  ? 686  ARG B CA  1 
ATOM   4739  C C   . ARG A 1 654 ? 183.031 194.925 249.859 1.00 75.36  ? 686  ARG B C   1 
ATOM   4740  O O   . ARG A 1 654 ? 183.094 194.032 250.706 1.00 75.36  ? 686  ARG B O   1 
ATOM   4741  C CB  . ARG A 1 654 ? 182.310 194.025 247.647 1.00 105.84 ? 686  ARG B CB  1 
ATOM   4742  C CG  . ARG A 1 654 ? 183.599 194.407 246.905 1.00 105.84 ? 686  ARG B CG  1 
ATOM   4743  C CD  . ARG A 1 654 ? 183.893 193.490 245.786 1.00 105.84 ? 686  ARG B CD  1 
ATOM   4744  N NE  . ARG A 1 654 ? 185.150 193.845 245.133 1.00 105.84 ? 686  ARG B NE  1 
ATOM   4745  C CZ  . ARG A 1 654 ? 185.791 193.133 244.198 1.00 105.84 ? 686  ARG B CZ  1 
ATOM   4746  N NH1 . ARG A 1 654 ? 186.907 193.640 243.738 1.00 105.84 ? 686  ARG B NH1 1 
ATOM   4747  N NH2 . ARG A 1 654 ? 185.329 191.976 243.759 1.00 105.84 ? 686  ARG B NH2 1 
ATOM   4748  N N   . SER A 1 655 ? 183.943 195.896 249.776 1.00 73.78  ? 687  SER B N   1 
ATOM   4749  C CA  . SER A 1 655 ? 185.105 195.919 250.649 1.00 73.78  ? 687  SER B CA  1 
ATOM   4750  C C   . SER A 1 655 ? 185.646 197.301 250.907 1.00 73.78  ? 687  SER B C   1 
ATOM   4751  O O   . SER A 1 655 ? 185.592 198.196 250.067 1.00 73.78  ? 687  SER B O   1 
ATOM   4752  C CB  . SER A 1 655 ? 186.225 195.067 250.117 1.00 98.27  ? 687  SER B CB  1 
ATOM   4753  O OG  . SER A 1 655 ? 187.350 195.144 250.974 1.00 98.27  ? 687  SER B OG  1 
ATOM   4754  N N   . VAL A 1 656 ? 186.195 197.456 252.093 1.00 70.22  ? 688  VAL B N   1 
ATOM   4755  C CA  . VAL A 1 656 ? 186.814 198.698 252.496 1.00 70.22  ? 688  VAL B CA  1 
ATOM   4756  C C   . VAL A 1 656 ? 188.185 198.894 251.865 1.00 70.22  ? 688  VAL B C   1 
ATOM   4757  O O   . VAL A 1 656 ? 188.694 200.015 251.825 1.00 70.22  ? 688  VAL B O   1 
ATOM   4758  C CB  . VAL A 1 656 ? 186.917 198.766 254.029 1.00 98.89  ? 688  VAL B CB  1 
ATOM   4759  C CG1 . VAL A 1 656 ? 185.518 198.677 254.623 1.00 98.89  ? 688  VAL B CG1 1 
ATOM   4760  C CG2 . VAL A 1 656 ? 187.812 197.629 254.564 1.00 98.89  ? 688  VAL B CG2 1 
ATOM   4761  N N   . SER A 1 657 ? 188.816 197.806 251.426 1.00 72.18  ? 689  SER B N   1 
ATOM   4762  C CA  . SER A 1 657 ? 190.136 197.931 250.840 1.00 72.18  ? 689  SER B CA  1 
ATOM   4763  C C   . SER A 1 657 ? 190.060 198.715 249.543 1.00 72.18  ? 689  SER B C   1 
ATOM   4764  O O   . SER A 1 657 ? 189.216 198.449 248.684 1.00 72.18  ? 689  SER B O   1 
ATOM   4765  C CB  . SER A 1 657 ? 190.734 196.566 250.570 1.00 96.14  ? 689  SER B CB  1 
ATOM   4766  O OG  . SER A 1 657 ? 190.954 195.854 251.764 1.00 96.14  ? 689  SER B OG  1 
ATOM   4767  N N   . ALA A 1 658 ? 191.028 199.598 249.336 1.00 64.83  ? 690  ALA B N   1 
ATOM   4768  C CA  . ALA A 1 658 ? 191.076 200.358 248.102 1.00 64.83  ? 690  ALA B CA  1 
ATOM   4769  C C   . ALA A 1 658 ? 191.276 199.385 246.957 1.00 64.83  ? 690  ALA B C   1 
ATOM   4770  O O   . ALA A 1 658 ? 191.893 198.340 247.165 1.00 64.83  ? 690  ALA B O   1 
ATOM   4771  C CB  . ALA A 1 658 ? 192.203 201.373 248.129 1.00 87.58  ? 690  ALA B CB  1 
ATOM   4772  N N   . PRO A 1 659 ? 190.778 199.659 245.745 1.00 70.90  ? 691  PRO B N   1 
ATOM   4773  C CA  . PRO A 1 659 ? 190.994 198.801 244.612 1.00 70.90  ? 691  PRO B CA  1 
ATOM   4774  C C   . PRO A 1 659 ? 192.506 198.632 244.441 1.00 70.90  ? 691  PRO B C   1 
ATOM   4775  O O   . PRO A 1 659 ? 193.270 199.595 244.538 1.00 70.90  ? 691  PRO B O   1 
ATOM   4776  C CB  . PRO A 1 659 ? 190.349 199.603 243.477 1.00 121.15 ? 691  PRO B CB  1 
ATOM   4777  C CG  . PRO A 1 659 ? 189.318 200.469 244.144 1.00 121.15 ? 691  PRO B CG  1 
ATOM   4778  C CD  . PRO A 1 659 ? 189.914 200.837 245.477 1.00 121.15 ? 691  PRO B CD  1 
ATOM   4779  N N   . ARG A 1 660 ? 192.940 197.409 244.159 1.00 76.76  ? 692  ARG B N   1 
ATOM   4780  C CA  . ARG A 1 660 ? 194.365 197.192 244.030 1.00 76.76  ? 692  ARG B CA  1 
ATOM   4781  C C   . ARG A 1 660 ? 194.858 197.881 242.777 1.00 76.76  ? 692  ARG B C   1 
ATOM   4782  O O   . ARG A 1 660 ? 194.160 197.920 241.755 1.00 76.76  ? 692  ARG B O   1 
ATOM   4783  C CB  . ARG A 1 660 ? 194.712 195.712 244.010 1.00 107.80 ? 692  ARG B CB  1 
ATOM   4784  C CG  . ARG A 1 660 ? 196.203 195.424 244.130 1.00 107.80 ? 692  ARG B CG  1 
ATOM   4785  C CD  . ARG A 1 660 ? 196.503 193.995 244.189 1.00 107.80 ? 692  ARG B CD  1 
ATOM   4786  N NE  . ARG A 1 660 ? 197.941 193.779 244.275 1.00 107.80 ? 692  ARG B NE  1 
ATOM   4787  C CZ  . ARG A 1 660 ? 198.558 192.582 244.291 1.00 107.80 ? 692  ARG B CZ  1 
ATOM   4788  N NH1 . ARG A 1 660 ? 199.878 192.535 244.370 1.00 107.80 ? 692  ARG B NH1 1 
ATOM   4789  N NH2 . ARG A 1 660 ? 197.861 191.465 244.228 1.00 107.80 ? 692  ARG B NH2 1 
ATOM   4790  N N   . PHE A 1 661 ? 196.070 198.428 242.868 1.00 73.38  ? 693  PHE B N   1 
ATOM   4791  C CA  . PHE A 1 661 ? 196.743 199.134 241.785 1.00 73.38  ? 693  PHE B CA  1 
ATOM   4792  C C   . PHE A 1 661 ? 196.055 200.447 241.421 1.00 73.38  ? 693  PHE B C   1 
ATOM   4793  O O   . PHE A 1 661 ? 196.283 200.964 240.326 1.00 73.38  ? 693  PHE B O   1 
ATOM   4794  C CB  . PHE A 1 661 ? 196.809 198.287 240.503 1.00 99.23  ? 693  PHE B CB  1 
ATOM   4795  C CG  . PHE A 1 661 ? 197.346 196.895 240.657 1.00 99.23  ? 693  PHE B CG  1 
ATOM   4796  C CD1 . PHE A 1 661 ? 198.666 196.653 240.998 1.00 99.23  ? 693  PHE B CD1 1 
ATOM   4797  C CD2 . PHE A 1 661 ? 196.504 195.812 240.459 1.00 99.23  ? 693  PHE B CD2 1 
ATOM   4798  C CE1 . PHE A 1 661 ? 199.128 195.360 241.132 1.00 99.23  ? 693  PHE B CE1 1 
ATOM   4799  C CE2 . PHE A 1 661 ? 196.963 194.526 240.589 1.00 99.23  ? 693  PHE B CE2 1 
ATOM   4800  C CZ  . PHE A 1 661 ? 198.275 194.298 240.924 1.00 99.23  ? 693  PHE B CZ  1 
ATOM   4801  N N   . ILE A 1 662 ? 195.270 201.022 242.342 1.00 76.94  ? 694  ILE B N   1 
ATOM   4802  C CA  . ILE A 1 662 ? 194.635 202.317 242.114 1.00 76.94  ? 694  ILE B CA  1 
ATOM   4803  C C   . ILE A 1 662 ? 195.583 203.477 242.464 1.00 76.94  ? 694  ILE B C   1 
ATOM   4804  O O   . ILE A 1 662 ? 195.291 204.657 242.224 1.00 76.94  ? 694  ILE B O   1 
ATOM   4805  C CB  . ILE A 1 662 ? 193.295 202.388 242.836 1.00 109.36 ? 694  ILE B CB  1 
ATOM   4806  C CG1 . ILE A 1 662 ? 192.457 203.427 242.160 1.00 109.36 ? 694  ILE B CG1 1 
ATOM   4807  C CG2 . ILE A 1 662 ? 193.483 202.705 244.342 1.00 109.36 ? 694  ILE B CG2 1 
ATOM   4808  C CD1 . ILE A 1 662 ? 191.042 203.339 242.444 1.00 109.36 ? 694  ILE B CD1 1 
ATOM   4809  N N   . SER A 1 663 ? 196.701 203.123 243.076 1.00 82.35  ? 695  SER B N   1 
ATOM   4810  C CA  . SER A 1 663 ? 197.781 204.033 243.433 1.00 82.35  ? 695  SER B CA  1 
ATOM   4811  C C   . SER A 1 663 ? 198.298 204.696 242.167 1.00 82.35  ? 695  SER B C   1 
ATOM   4812  O O   . SER A 1 663 ? 198.368 204.017 241.133 1.00 82.35  ? 695  SER B O   1 
ATOM   4813  C CB  . SER A 1 663 ? 198.923 203.249 244.065 1.00 109.69 ? 695  SER B CB  1 
ATOM   4814  O OG  . SER A 1 663 ? 200.071 204.053 244.245 1.00 109.69 ? 695  SER B OG  1 
ATOM   4815  N N   . PRO A 1 664 ? 198.719 205.985 242.194 1.00 84.16  ? 696  PRO B N   1 
ATOM   4816  C CA  . PRO A 1 664 ? 199.239 206.717 241.052 1.00 84.16  ? 696  PRO B CA  1 
ATOM   4817  C C   . PRO A 1 664 ? 200.443 206.016 240.465 1.00 84.16  ? 696  PRO B C   1 
ATOM   4818  O O   . PRO A 1 664 ? 200.674 206.065 239.257 1.00 84.16  ? 696  PRO B O   1 
ATOM   4819  C CB  . PRO A 1 664 ? 199.607 208.083 241.645 1.00 143.81 ? 696  PRO B CB  1 
ATOM   4820  C CG  . PRO A 1 664 ? 199.752 207.844 243.129 1.00 143.81 ? 696  PRO B CG  1 
ATOM   4821  C CD  . PRO A 1 664 ? 198.720 206.774 243.449 1.00 143.81 ? 696  PRO B CD  1 
ATOM   4822  N N   . ALA A 1 665 ? 201.126 205.211 241.286 1.00 86.77  ? 697  ALA B N   1 
ATOM   4823  C CA  . ALA A 1 665 ? 202.289 204.490 240.823 1.00 86.77  ? 697  ALA B CA  1 
ATOM   4824  C C   . ALA A 1 665 ? 201.945 203.596 239.632 1.00 86.77  ? 697  ALA B C   1 
ATOM   4825  O O   . ALA A 1 665 ? 202.787 203.382 238.757 1.00 86.77  ? 697  ALA B O   1 
ATOM   4826  C CB  . ALA A 1 665 ? 202.850 203.653 241.955 1.00 117.22 ? 697  ALA B CB  1 
ATOM   4827  N N   . SER A 1 666 ? 200.724 203.042 239.612 1.00 88.20  ? 698  SER B N   1 
ATOM   4828  C CA  . SER A 1 666 ? 200.294 202.188 238.516 1.00 88.20  ? 698  SER B CA  1 
ATOM   4829  C C   . SER A 1 666 ? 199.365 202.932 237.561 1.00 88.20  ? 698  SER B C   1 
ATOM   4830  O O   . SER A 1 666 ? 199.351 202.655 236.355 1.00 88.20  ? 698  SER B O   1 
ATOM   4831  C CB  . SER A 1 666 ? 199.565 200.968 239.048 1.00 117.48 ? 698  SER B CB  1 
ATOM   4832  O OG  . SER A 1 666 ? 200.405 200.142 239.808 1.00 117.48 ? 698  SER B OG  1 
ATOM   4833  N N   . GLN A 1 667 ? 198.606 203.896 238.084 1.00 90.11  ? 699  GLN B N   1 
ATOM   4834  C CA  . GLN A 1 667 ? 197.614 204.575 237.261 1.00 90.11  ? 699  GLN B CA  1 
ATOM   4835  C C   . GLN A 1 667 ? 198.240 205.451 236.207 1.00 90.11  ? 699  GLN B C   1 
ATOM   4836  O O   . GLN A 1 667 ? 197.723 205.568 235.092 1.00 90.11  ? 699  GLN B O   1 
ATOM   4837  C CB  . GLN A 1 667 ? 196.691 205.388 238.147 1.00 122.48 ? 699  GLN B CB  1 
ATOM   4838  C CG  . GLN A 1 667 ? 195.842 204.539 239.037 1.00 122.48 ? 699  GLN B CG  1 
ATOM   4839  C CD  . GLN A 1 667 ? 194.829 203.764 238.287 1.00 122.48 ? 699  GLN B CD  1 
ATOM   4840  O OE1 . GLN A 1 667 ? 194.116 204.332 237.474 1.00 122.48 ? 699  GLN B OE1 1 
ATOM   4841  N NE2 . GLN A 1 667 ? 194.745 202.471 238.515 1.00 122.48 ? 699  GLN B NE2 1 
ATOM   4842  N N   . LEU A 1 668 ? 199.369 206.062 236.527 1.00 92.81  ? 700  LEU B N   1 
ATOM   4843  C CA  . LEU A 1 668 ? 199.985 206.899 235.534 1.00 92.81  ? 700  LEU B CA  1 
ATOM   4844  C C   . LEU A 1 668 ? 200.487 206.010 234.413 1.00 92.81  ? 700  LEU B C   1 
ATOM   4845  O O   . LEU A 1 668 ? 200.307 206.332 233.237 1.00 92.81  ? 700  LEU B O   1 
ATOM   4846  C CB  . LEU A 1 668 ? 201.099 207.702 236.191 1.00 131.92 ? 700  LEU B CB  1 
ATOM   4847  C CG  . LEU A 1 668 ? 200.605 208.750 237.234 1.00 131.92 ? 700  LEU B CG  1 
ATOM   4848  C CD1 . LEU A 1 668 ? 201.813 209.303 237.983 1.00 131.92 ? 700  LEU B CD1 1 
ATOM   4849  C CD2 . LEU A 1 668 ? 199.798 209.891 236.532 1.00 131.92 ? 700  LEU B CD2 1 
ATOM   4850  N N   . ALA A 1 669 ? 201.035 204.840 234.763 1.00 93.01  ? 701  ALA B N   1 
ATOM   4851  C CA  . ALA A 1 669 ? 201.502 203.918 233.748 1.00 93.01  ? 701  ALA B CA  1 
ATOM   4852  C C   . ALA A 1 669 ? 200.344 203.520 232.857 1.00 93.01  ? 701  ALA B C   1 
ATOM   4853  O O   . ALA A 1 669 ? 200.481 203.535 231.644 1.00 93.01  ? 701  ALA B O   1 
ATOM   4854  C CB  . ALA A 1 669 ? 202.126 202.688 234.373 1.00 125.65 ? 701  ALA B CB  1 
ATOM   4855  N N   . ILE A 1 670 ? 199.147 203.328 233.410 1.00 92.70  ? 702  ILE B N   1 
ATOM   4856  C CA  . ILE A 1 670 ? 198.042 202.939 232.542 1.00 92.70  ? 702  ILE B CA  1 
ATOM   4857  C C   . ILE A 1 670 ? 197.823 203.981 231.485 1.00 92.70  ? 702  ILE B C   1 
ATOM   4858  O O   . ILE A 1 670 ? 197.658 203.641 230.307 1.00 92.70  ? 702  ILE B O   1 
ATOM   4859  C CB  . ILE A 1 670 ? 196.721 202.756 233.307 1.00 131.76 ? 702  ILE B CB  1 
ATOM   4860  C CG1 . ILE A 1 670 ? 196.832 201.526 234.214 1.00 131.76 ? 702  ILE B CG1 1 
ATOM   4861  C CG2 . ILE A 1 670 ? 195.516 202.666 232.306 1.00 131.76 ? 702  ILE B CG2 1 
ATOM   4862  C CD1 . ILE A 1 670 ? 195.719 201.404 235.236 1.00 131.76 ? 702  ILE B CD1 1 
ATOM   4863  N N   . THR A 1 671 ? 197.824 205.245 231.884 1.00 94.32  ? 703  THR B N   1 
ATOM   4864  C CA  . THR A 1 671 ? 197.614 206.286 230.902 1.00 94.32  ? 703  THR B CA  1 
ATOM   4865  C C   . THR A 1 671 ? 198.690 206.220 229.831 1.00 94.32  ? 703  THR B C   1 
ATOM   4866  O O   . THR A 1 671 ? 198.394 206.269 228.631 1.00 94.32  ? 703  THR B O   1 
ATOM   4867  C CB  . THR A 1 671 ? 197.657 207.687 231.540 1.00 129.11 ? 703  THR B CB  1 
ATOM   4868  O OG1 . THR A 1 671 ? 196.627 207.820 232.514 1.00 129.11 ? 703  THR B OG1 1 
ATOM   4869  C CG2 . THR A 1 671 ? 197.425 208.712 230.482 1.00 129.11 ? 703  THR B CG2 1 
ATOM   4870  N N   . PHE A 1 672 ? 199.943 206.066 230.248 1.00 94.58  ? 704  PHE B N   1 
ATOM   4871  C CA  . PHE A 1 672 ? 201.025 206.071 229.282 1.00 94.58  ? 704  PHE B CA  1 
ATOM   4872  C C   . PHE A 1 672 ? 201.035 204.834 228.404 1.00 94.58  ? 704  PHE B C   1 
ATOM   4873  O O   . PHE A 1 672 ? 201.451 204.906 227.248 1.00 94.58  ? 704  PHE B O   1 
ATOM   4874  C CB  . PHE A 1 672 ? 202.358 206.270 229.979 1.00 127.90 ? 704  PHE B CB  1 
ATOM   4875  C CG  . PHE A 1 672 ? 202.489 207.678 230.488 1.00 127.90 ? 704  PHE B CG  1 
ATOM   4876  C CD1 . PHE A 1 672 ? 202.582 208.749 229.605 1.00 127.90 ? 704  PHE B CD1 1 
ATOM   4877  C CD2 . PHE A 1 672 ? 202.476 207.946 231.843 1.00 127.90 ? 704  PHE B CD2 1 
ATOM   4878  C CE1 . PHE A 1 672 ? 202.661 210.043 230.072 1.00 127.90 ? 704  PHE B CE1 1 
ATOM   4879  C CE2 . PHE A 1 672 ? 202.555 209.237 232.313 1.00 127.90 ? 704  PHE B CE2 1 
ATOM   4880  C CZ  . PHE A 1 672 ? 202.648 210.287 231.426 1.00 127.90 ? 704  PHE B CZ  1 
ATOM   4881  N N   . SER A 1 673 ? 200.560 203.716 228.922 1.00 95.46  ? 705  SER B N   1 
ATOM   4882  C CA  . SER A 1 673 ? 200.473 202.496 228.150 1.00 95.46  ? 705  SER B CA  1 
ATOM   4883  C C   . SER A 1 673 ? 199.466 202.687 227.044 1.00 95.46  ? 705  SER B C   1 
ATOM   4884  O O   . SER A 1 673 ? 199.757 202.367 225.895 1.00 95.46  ? 705  SER B O   1 
ATOM   4885  C CB  . SER A 1 673 ? 200.083 201.309 229.034 1.00 30.00  ? 705  SER B CB  1 
ATOM   4886  O OG  . SER A 1 673 ? 198.796 201.493 229.595 1.00 30.00  ? 705  SER B OG  1 
ATOM   4887  N N   . LEU A 1 674 ? 198.313 203.266 227.361 1.00 95.54  ? 706  LEU B N   1 
ATOM   4888  C CA  . LEU A 1 674 ? 197.302 203.481 226.340 1.00 95.54  ? 706  LEU B CA  1 
ATOM   4889  C C   . LEU A 1 674 ? 197.859 204.391 225.252 1.00 95.54  ? 706  LEU B C   1 
ATOM   4890  O O   . LEU A 1 674 ? 197.599 204.181 224.055 1.00 95.54  ? 706  LEU B O   1 
ATOM   4891  C CB  . LEU A 1 674 ? 196.068 204.120 226.972 1.00 135.80 ? 706  LEU B CB  1 
ATOM   4892  C CG  . LEU A 1 674 ? 195.248 203.248 227.952 1.00 135.80 ? 706  LEU B CG  1 
ATOM   4893  C CD1 . LEU A 1 674 ? 194.209 204.129 228.627 1.00 135.80 ? 706  LEU B CD1 1 
ATOM   4894  C CD2 . LEU A 1 674 ? 194.570 202.108 227.210 1.00 135.80 ? 706  LEU B CD2 1 
ATOM   4895  N N   . ILE A 1 675 ? 198.669 205.371 225.663 1.00 95.22  ? 707  ILE B N   1 
ATOM   4896  C CA  . ILE A 1 675 ? 199.304 206.271 224.717 1.00 95.22  ? 707  ILE B CA  1 
ATOM   4897  C C   . ILE A 1 675 ? 200.275 205.486 223.838 1.00 95.22  ? 707  ILE B C   1 
ATOM   4898  O O   . ILE A 1 675 ? 200.264 205.664 222.617 1.00 95.22  ? 707  ILE B O   1 
ATOM   4899  C CB  . ILE A 1 675 ? 200.017 207.448 225.432 1.00 135.34 ? 707  ILE B CB  1 
ATOM   4900  C CG1 . ILE A 1 675 ? 198.937 208.371 226.096 1.00 135.34 ? 707  ILE B CG1 1 
ATOM   4901  C CG2 . ILE A 1 675 ? 200.885 208.230 224.423 1.00 135.34 ? 707  ILE B CG2 1 
ATOM   4902  C CD1 . ILE A 1 675 ? 199.466 209.405 227.094 1.00 135.34 ? 707  ILE B CD1 1 
ATOM   4903  N N   . SER A 1 676 ? 201.089 204.617 224.437 1.00 93.90  ? 708  SER B N   1 
ATOM   4904  C CA  . SER A 1 676 ? 202.025 203.817 223.672 1.00 93.90  ? 708  SER B CA  1 
ATOM   4905  C C   . SER A 1 676 ? 201.321 202.866 222.732 1.00 93.90  ? 708  SER B C   1 
ATOM   4906  O O   . SER A 1 676 ? 201.777 202.658 221.608 1.00 93.90  ? 708  SER B O   1 
ATOM   4907  C CB  . SER A 1 676 ? 202.957 203.045 224.580 1.00 125.07 ? 708  SER B CB  1 
ATOM   4908  O OG  . SER A 1 676 ? 203.822 203.907 225.273 1.00 125.07 ? 708  SER B OG  1 
ATOM   4909  N N   . LEU A 1 677 ? 200.170 202.336 223.122 1.00 93.43  ? 709  LEU B N   1 
ATOM   4910  C CA  . LEU A 1 677 ? 199.501 201.425 222.219 1.00 93.43  ? 709  LEU B CA  1 
ATOM   4911  C C   . LEU A 1 677 ? 199.158 202.166 220.948 1.00 93.43  ? 709  LEU B C   1 
ATOM   4912  O O   . LEU A 1 677 ? 199.339 201.642 219.837 1.00 93.43  ? 709  LEU B O   1 
ATOM   4913  C CB  . LEU A 1 677 ? 198.212 200.895 222.842 1.00 132.80 ? 709  LEU B CB  1 
ATOM   4914  C CG  . LEU A 1 677 ? 198.345 199.962 224.063 1.00 132.80 ? 709  LEU B CG  1 
ATOM   4915  C CD1 . LEU A 1 677 ? 196.959 199.697 224.618 1.00 132.80 ? 709  LEU B CD1 1 
ATOM   4916  C CD2 . LEU A 1 677 ? 199.039 198.669 223.686 1.00 132.80 ? 709  LEU B CD2 1 
ATOM   4917  N N   . GLN A 1 678 ? 198.730 203.416 221.083 1.00 92.46  ? 710  GLN B N   1 
ATOM   4918  C CA  . GLN A 1 678 ? 198.458 204.146 219.877 1.00 92.46  ? 710  GLN B CA  1 
ATOM   4919  C C   . GLN A 1 678 ? 199.751 204.456 219.143 1.00 92.46  ? 710  GLN B C   1 
ATOM   4920  O O   . GLN A 1 678 ? 199.802 204.325 217.923 1.00 92.46  ? 710  GLN B O   1 
ATOM   4921  C CB  . GLN A 1 678 ? 197.773 205.454 220.123 1.00 125.67 ? 710  GLN B CB  1 
ATOM   4922  C CG  . GLN A 1 678 ? 197.322 206.079 218.834 1.00 125.67 ? 710  GLN B CG  1 
ATOM   4923  C CD  . GLN A 1 678 ? 196.586 207.282 219.059 1.00 125.67 ? 710  GLN B CD  1 
ATOM   4924  O OE1 . GLN A 1 678 ? 197.022 208.048 219.915 1.00 125.67 ? 710  GLN B OE1 1 
ATOM   4925  N NE2 . GLN A 1 678 ? 195.485 207.476 218.339 1.00 125.67 ? 710  GLN B NE2 1 
ATOM   4926  N N   . LEU A 1 679 ? 200.829 204.787 219.865 1.00 92.17  ? 711  LEU B N   1 
ATOM   4927  C CA  . LEU A 1 679 ? 202.055 205.159 219.172 1.00 92.17  ? 711  LEU B CA  1 
ATOM   4928  C C   . LEU A 1 679 ? 202.512 204.023 218.309 1.00 92.17  ? 711  LEU B C   1 
ATOM   4929  O O   . LEU A 1 679 ? 202.989 204.240 217.194 1.00 92.17  ? 711  LEU B O   1 
ATOM   4930  C CB  . LEU A 1 679 ? 203.213 205.441 220.145 1.00 131.01 ? 711  LEU B CB  1 
ATOM   4931  C CG  . LEU A 1 679 ? 203.131 206.677 221.056 1.00 131.01 ? 711  LEU B CG  1 
ATOM   4932  C CD1 . LEU A 1 679 ? 204.297 206.647 222.044 1.00 131.01 ? 711  LEU B CD1 1 
ATOM   4933  C CD2 . LEU A 1 679 ? 203.196 207.927 220.249 1.00 131.01 ? 711  LEU B CD2 1 
ATOM   4934  N N   . LEU A 1 680 ? 202.354 202.811 218.804 1.00 91.78  ? 712  LEU B N   1 
ATOM   4935  C CA  . LEU A 1 680 ? 202.758 201.660 218.045 1.00 91.78  ? 712  LEU B CA  1 
ATOM   4936  C C   . LEU A 1 680 ? 201.886 201.512 216.806 1.00 91.78  ? 712  LEU B C   1 
ATOM   4937  O O   . LEU A 1 680 ? 202.401 201.235 215.718 1.00 91.78  ? 712  LEU B O   1 
ATOM   4938  C CB  . LEU A 1 680 ? 202.650 200.436 218.948 1.00 130.45 ? 712  LEU B CB  1 
ATOM   4939  C CG  . LEU A 1 680 ? 203.655 200.391 220.144 1.00 130.45 ? 712  LEU B CG  1 
ATOM   4940  C CD1 . LEU A 1 680 ? 203.254 199.260 221.079 1.00 130.45 ? 712  LEU B CD1 1 
ATOM   4941  C CD2 . LEU A 1 680 ? 205.091 200.195 219.641 1.00 130.45 ? 712  LEU B CD2 1 
ATOM   4942  N N   . GLY A 1 681 ? 200.577 201.743 216.941 1.00 89.18  ? 713  GLY B N   1 
ATOM   4943  C CA  . GLY A 1 681 ? 199.690 201.671 215.787 1.00 89.18  ? 713  GLY B CA  1 
ATOM   4944  C C   . GLY A 1 681 ? 200.040 202.739 214.749 1.00 89.18  ? 713  GLY B C   1 
ATOM   4945  O O   . GLY A 1 681 ? 199.964 202.502 213.537 1.00 89.18  ? 713  GLY B O   1 
ATOM   4946  N N   . ILE A 1 682 ? 200.457 203.909 215.226 1.00 89.47  ? 714  ILE B N   1 
ATOM   4947  C CA  . ILE A 1 682 ? 200.815 205.007 214.348 1.00 89.47  ? 714  ILE B CA  1 
ATOM   4948  C C   . ILE A 1 682 ? 202.080 204.624 213.611 1.00 89.47  ? 714  ILE B C   1 
ATOM   4949  O O   . ILE A 1 682 ? 202.190 204.838 212.401 1.00 89.47  ? 714  ILE B O   1 
ATOM   4950  C CB  . ILE A 1 682 ? 201.015 206.336 215.087 1.00 127.17 ? 714  ILE B CB  1 
ATOM   4951  C CG1 . ILE A 1 682 ? 199.683 206.801 215.708 1.00 127.17 ? 714  ILE B CG1 1 
ATOM   4952  C CG2 . ILE A 1 682 ? 201.466 207.363 214.032 1.00 127.17 ? 714  ILE B CG2 1 
ATOM   4953  C CD1 . ILE A 1 682 ? 199.801 207.952 216.723 1.00 127.17 ? 714  ILE B CD1 1 
ATOM   4954  N N   . CYS A 1 683 ? 203.038 204.052 214.336 1.00 89.64  ? 715  CYS B N   1 
ATOM   4955  C CA  . CYS A 1 683 ? 204.278 203.641 213.724 1.00 89.64  ? 715  CYS B CA  1 
ATOM   4956  C C   . CYS A 1 683 ? 203.964 202.695 212.589 1.00 89.64  ? 715  CYS B C   1 
ATOM   4957  O O   . CYS A 1 683 ? 204.529 202.836 211.508 1.00 89.64  ? 715  CYS B O   1 
ATOM   4958  C CB  . CYS A 1 683 ? 205.189 202.973 214.736 1.00 119.40 ? 715  CYS B CB  1 
ATOM   4959  S SG  . CYS A 1 683 ? 205.804 204.111 215.992 1.00 119.40 ? 715  CYS B SG  1 
ATOM   4960  N N   . VAL A 1 684 ? 203.000 201.797 212.782 1.00 88.66  ? 716  VAL B N   1 
ATOM   4961  C CA  . VAL A 1 684 ? 202.646 200.919 211.691 1.00 88.66  ? 716  VAL B CA  1 
ATOM   4962  C C   . VAL A 1 684 ? 202.142 201.732 210.527 1.00 88.66  ? 716  VAL B C   1 
ATOM   4963  O O   . VAL A 1 684 ? 202.587 201.522 209.402 1.00 88.66  ? 716  VAL B O   1 
ATOM   4964  C CB  . VAL A 1 684 ? 201.569 199.905 212.091 1.00 124.85 ? 716  VAL B CB  1 
ATOM   4965  C CG1 . VAL A 1 684 ? 201.065 199.153 210.848 1.00 124.85 ? 716  VAL B CG1 1 
ATOM   4966  C CG2 . VAL A 1 684 ? 202.157 198.940 213.094 1.00 124.85 ? 716  VAL B CG2 1 
ATOM   4967  N N   . TRP A 1 685 ? 201.287 202.717 210.776 1.00 82.88  ? 717  TRP B N   1 
ATOM   4968  C CA  . TRP A 1 685 ? 200.802 203.510 209.661 1.00 82.88  ? 717  TRP B CA  1 
ATOM   4969  C C   . TRP A 1 685 ? 201.948 204.176 208.910 1.00 82.88  ? 717  TRP B C   1 
ATOM   4970  O O   . TRP A 1 685 ? 201.934 204.221 207.675 1.00 82.88  ? 717  TRP B O   1 
ATOM   4971  C CB  . TRP A 1 685 ? 199.756 204.519 210.106 1.00 110.96 ? 717  TRP B CB  1 
ATOM   4972  C CG  . TRP A 1 685 ? 198.465 203.837 210.371 1.00 110.96 ? 717  TRP B CG  1 
ATOM   4973  C CD1 . TRP A 1 685 ? 197.855 203.664 211.571 1.00 110.96 ? 717  TRP B CD1 1 
ATOM   4974  C CD2 . TRP A 1 685 ? 197.609 203.193 209.390 1.00 110.96 ? 717  TRP B CD2 1 
ATOM   4975  N NE1 . TRP A 1 685 ? 196.690 202.953 211.408 1.00 110.96 ? 717  TRP B NE1 1 
ATOM   4976  C CE2 . TRP A 1 685 ? 196.532 202.655 210.081 1.00 110.96 ? 717  TRP B CE2 1 
ATOM   4977  C CE3 . TRP A 1 685 ? 197.677 203.027 207.998 1.00 110.96 ? 717  TRP B CE3 1 
ATOM   4978  C CZ2 . TRP A 1 685 ? 195.528 201.954 209.439 1.00 110.96 ? 717  TRP B CZ2 1 
ATOM   4979  C CZ3 . TRP A 1 685 ? 196.663 202.327 207.362 1.00 110.96 ? 717  TRP B CZ3 1 
ATOM   4980  C CH2 . TRP A 1 685 ? 195.620 201.804 208.070 1.00 110.96 ? 717  TRP B CH2 1 
ATOM   4981  N N   . PHE A 1 686 ? 202.970 204.629 209.632 1.00 87.23  ? 718  PHE B N   1 
ATOM   4982  C CA  . PHE A 1 686 ? 204.125 205.216 208.971 1.00 87.23  ? 718  PHE B CA  1 
ATOM   4983  C C   . PHE A 1 686 ? 204.870 204.183 208.151 1.00 87.23  ? 718  PHE B C   1 
ATOM   4984  O O   . PHE A 1 686 ? 205.446 204.508 207.119 1.00 87.23  ? 718  PHE B O   1 
ATOM   4985  C CB  . PHE A 1 686 ? 205.142 205.788 209.950 1.00 117.96 ? 718  PHE B CB  1 
ATOM   4986  C CG  . PHE A 1 686 ? 204.853 207.110 210.521 1.00 117.96 ? 718  PHE B CG  1 
ATOM   4987  C CD1 . PHE A 1 686 ? 204.955 208.228 209.734 1.00 117.96 ? 718  PHE B CD1 1 
ATOM   4988  C CD2 . PHE A 1 686 ? 204.520 207.272 211.849 1.00 117.96 ? 718  PHE B CD2 1 
ATOM   4989  C CE1 . PHE A 1 686 ? 204.735 209.463 210.269 1.00 117.96 ? 718  PHE B CE1 1 
ATOM   4990  C CE2 . PHE A 1 686 ? 204.300 208.529 212.375 1.00 117.96 ? 718  PHE B CE2 1 
ATOM   4991  C CZ  . PHE A 1 686 ? 204.408 209.614 211.588 1.00 117.96 ? 718  PHE B CZ  1 
ATOM   4992  N N   . VAL A 1 687 ? 204.926 202.956 208.633 1.00 87.74  ? 719  VAL B N   1 
ATOM   4993  C CA  . VAL A 1 687 ? 205.626 201.902 207.931 1.00 87.74  ? 719  VAL B CA  1 
ATOM   4994  C C   . VAL A 1 687 ? 204.924 201.482 206.656 1.00 87.74  ? 719  VAL B C   1 
ATOM   4995  O O   . VAL A 1 687 ? 205.574 201.285 205.627 1.00 87.74  ? 719  VAL B O   1 
ATOM   4996  C CB  . VAL A 1 687 ? 205.829 200.682 208.849 1.00 123.56 ? 719  VAL B CB  1 
ATOM   4997  C CG1 . VAL A 1 687 ? 206.384 199.486 208.064 1.00 123.56 ? 719  VAL B CG1 1 
ATOM   4998  C CG2 . VAL A 1 687 ? 206.815 201.065 209.945 1.00 123.56 ? 719  VAL B CG2 1 
ATOM   4999  N N   . VAL A 1 688 ? 203.612 201.317 206.720 1.00 86.77  ? 720  VAL B N   1 
ATOM   5000  C CA  . VAL A 1 688 ? 202.891 200.874 205.540 1.00 86.77  ? 720  VAL B CA  1 
ATOM   5001  C C   . VAL A 1 688 ? 202.782 201.974 204.492 1.00 86.77  ? 720  VAL B C   1 
ATOM   5002  O O   . VAL A 1 688 ? 202.810 201.689 203.296 1.00 86.77  ? 720  VAL B O   1 
ATOM   5003  C CB  . VAL A 1 688 ? 201.497 200.309 205.905 1.00 122.19 ? 720  VAL B CB  1 
ATOM   5004  C CG1 . VAL A 1 688 ? 201.675 199.144 206.868 1.00 122.19 ? 720  VAL B CG1 1 
ATOM   5005  C CG2 . VAL A 1 688 ? 200.624 201.363 206.531 1.00 122.19 ? 720  VAL B CG2 1 
ATOM   5006  N N   . ASP A 1 689 ? 202.654 203.225 204.921 1.00 82.58  ? 721  ASP B N   1 
ATOM   5007  C CA  . ASP A 1 689 ? 202.560 204.316 203.978 1.00 82.58  ? 721  ASP B CA  1 
ATOM   5008  C C   . ASP A 1 689 ? 203.155 205.587 204.618 1.00 82.58  ? 721  ASP B C   1 
ATOM   5009  O O   . ASP A 1 689 ? 202.402 206.342 205.239 1.00 82.58  ? 721  ASP B O   1 
ATOM   5010  C CB  . ASP A 1 689 ? 201.098 204.517 203.586 1.00 105.16 ? 721  ASP B CB  1 
ATOM   5011  C CG  . ASP A 1 689 ? 200.915 205.501 202.468 1.00 105.16 ? 721  ASP B CG  1 
ATOM   5012  O OD1 . ASP A 1 689 ? 201.900 206.031 202.016 1.00 105.16 ? 721  ASP B OD1 1 
ATOM   5013  O OD2 . ASP A 1 689 ? 199.792 205.695 202.042 1.00 105.16 ? 721  ASP B OD2 1 
ATOM   5014  N N   . PRO A 1 690 ? 204.490 205.822 204.476 1.00 85.34  ? 722  PRO B N   1 
ATOM   5015  C CA  . PRO A 1 690 ? 205.334 206.878 205.067 1.00 85.34  ? 722  PRO B CA  1 
ATOM   5016  C C   . PRO A 1 690 ? 204.972 208.306 204.668 1.00 85.34  ? 722  PRO B C   1 
ATOM   5017  O O   . PRO A 1 690 ? 204.301 208.540 203.659 1.00 85.34  ? 722  PRO B O   1 
ATOM   5018  C CB  . PRO A 1 690 ? 206.736 206.546 204.539 1.00 145.83 ? 722  PRO B CB  1 
ATOM   5019  C CG  . PRO A 1 690 ? 206.690 205.090 204.159 1.00 145.83 ? 722  PRO B CG  1 
ATOM   5020  C CD  . PRO A 1 690 ? 205.290 204.843 203.680 1.00 145.83 ? 722  PRO B CD  1 
ATOM   5021  N N   . SER A 1 691 ? 205.409 209.259 205.491 1.00 82.60  ? 723  SER B N   1 
ATOM   5022  C CA  . SER A 1 691 ? 205.180 210.675 205.253 1.00 82.60  ? 723  SER B CA  1 
ATOM   5023  C C   . SER A 1 691 ? 205.786 211.174 203.964 1.00 82.60  ? 723  SER B C   1 
ATOM   5024  O O   . SER A 1 691 ? 206.971 210.955 203.704 1.00 82.60  ? 723  SER B O   1 
ATOM   5025  C CB  . SER A 1 691 ? 205.882 211.460 206.334 1.00 110.02 ? 723  SER B CB  1 
ATOM   5026  O OG  . SER A 1 691 ? 205.365 211.218 207.590 1.00 110.02 ? 723  SER B OG  1 
ATOM   5027  N N   . HIS A 1 692 ? 204.993 211.917 203.209 1.00 83.62  ? 724  HIS B N   1 
ATOM   5028  C CA  . HIS A 1 692 ? 205.442 212.553 201.989 1.00 83.62  ? 724  HIS B CA  1 
ATOM   5029  C C   . HIS A 1 692 ? 204.758 213.891 201.766 1.00 83.62  ? 724  HIS B C   1 
ATOM   5030  O O   . HIS A 1 692 ? 203.546 214.022 201.965 1.00 83.62  ? 724  HIS B O   1 
ATOM   5031  C CB  . HIS A 1 692 ? 205.196 211.682 200.753 1.00 111.07 ? 724  HIS B CB  1 
ATOM   5032  C CG  . HIS A 1 692 ? 205.965 210.392 200.676 1.00 111.07 ? 724  HIS B CG  1 
ATOM   5033  N ND1 . HIS A 1 692 ? 205.595 209.244 201.343 1.00 111.07 ? 724  HIS B ND1 1 
ATOM   5034  C CD2 . HIS A 1 692 ? 207.092 210.084 200.001 1.00 111.07 ? 724  HIS B CD2 1 
ATOM   5035  C CE1 . HIS A 1 692 ? 206.456 208.288 201.077 1.00 111.07 ? 724  HIS B CE1 1 
ATOM   5036  N NE2 . HIS A 1 692 ? 207.377 208.766 200.260 1.00 111.07 ? 724  HIS B NE2 1 
ATOM   5037  N N   . SER A 1 693 ? 205.519 214.849 201.264 1.00 85.17  ? 725  SER B N   1 
ATOM   5038  C CA  . SER A 1 693 ? 204.993 216.136 200.841 1.00 85.17  ? 725  SER B CA  1 
ATOM   5039  C C   . SER A 1 693 ? 204.848 215.971 199.343 1.00 85.17  ? 725  SER B C   1 
ATOM   5040  O O   . SER A 1 693 ? 205.827 215.652 198.661 1.00 85.17  ? 725  SER B O   1 
ATOM   5041  C CB  . SER A 1 693 ? 205.931 217.267 201.208 1.00 113.44 ? 725  SER B CB  1 
ATOM   5042  O OG  . SER A 1 693 ? 205.468 218.483 200.694 1.00 113.44 ? 725  SER B OG  1 
ATOM   5043  N N   . VAL A 1 694 ? 203.622 216.048 198.845 1.00 85.18  ? 726  VAL B N   1 
ATOM   5044  C CA  . VAL A 1 694 ? 203.378 215.740 197.445 1.00 85.18  ? 726  VAL B CA  1 
ATOM   5045  C C   . VAL A 1 694 ? 202.576 216.786 196.727 1.00 85.18  ? 726  VAL B C   1 
ATOM   5046  O O   . VAL A 1 694 ? 201.888 217.597 197.348 1.00 85.18  ? 726  VAL B O   1 
ATOM   5047  C CB  . VAL A 1 694 ? 202.593 214.420 197.330 1.00 119.95 ? 726  VAL B CB  1 
ATOM   5048  C CG1 . VAL A 1 694 ? 203.385 213.291 197.992 1.00 119.95 ? 726  VAL B CG1 1 
ATOM   5049  C CG2 . VAL A 1 694 ? 201.184 214.591 197.964 1.00 119.95 ? 726  VAL B CG2 1 
ATOM   5050  N N   . VAL A 1 695 ? 202.610 216.738 195.407 1.00 82.38  ? 727  VAL B N   1 
ATOM   5051  C CA  . VAL A 1 695 ? 201.751 217.623 194.670 1.00 82.38  ? 727  VAL B CA  1 
ATOM   5052  C C   . VAL A 1 695 ? 200.731 216.846 193.876 1.00 82.38  ? 727  VAL B C   1 
ATOM   5053  O O   . VAL A 1 695 ? 201.058 215.957 193.091 1.00 82.38  ? 727  VAL B O   1 
ATOM   5054  C CB  . VAL A 1 695 ? 202.532 218.565 193.767 1.00 116.01 ? 727  VAL B CB  1 
ATOM   5055  C CG1 . VAL A 1 695 ? 201.570 219.427 192.996 1.00 116.01 ? 727  VAL B CG1 1 
ATOM   5056  C CG2 . VAL A 1 695 ? 203.409 219.446 194.609 1.00 116.01 ? 727  VAL B CG2 1 
ATOM   5057  N N   . ASP A 1 696 ? 199.495 217.201 194.138 1.00 78.26  ? 728  ASP B N   1 
ATOM   5058  C CA  . ASP A 1 696 ? 198.311 216.663 193.527 1.00 78.26  ? 728  ASP B CA  1 
ATOM   5059  C C   . ASP A 1 696 ? 198.042 217.418 192.256 1.00 78.26  ? 728  ASP B C   1 
ATOM   5060  O O   . ASP A 1 696 ? 197.871 218.631 192.286 1.00 78.26  ? 728  ASP B O   1 
ATOM   5061  C CB  . ASP A 1 696 ? 197.144 216.799 194.485 1.00 99.66  ? 728  ASP B CB  1 
ATOM   5062  C CG  . ASP A 1 696 ? 195.858 216.194 193.998 1.00 99.66  ? 728  ASP B CG  1 
ATOM   5063  O OD1 . ASP A 1 696 ? 195.635 216.131 192.771 1.00 99.66  ? 728  ASP B OD1 1 
ATOM   5064  O OD2 . ASP A 1 696 ? 195.095 215.751 194.856 1.00 99.66  ? 728  ASP B OD2 1 
ATOM   5065  N N   . PHE A 1 697 ? 198.083 216.803 191.089 1.00 76.60  ? 729  PHE B N   1 
ATOM   5066  C CA  . PHE A 1 697 ? 197.688 217.537 189.885 1.00 76.60  ? 729  PHE B CA  1 
ATOM   5067  C C   . PHE A 1 697 ? 196.241 217.243 189.535 1.00 76.60  ? 729  PHE B C   1 
ATOM   5068  O O   . PHE A 1 697 ? 195.534 218.084 188.999 1.00 76.60  ? 729  PHE B O   1 
ATOM   5069  C CB  . PHE A 1 697 ? 198.633 217.156 188.762 1.00 103.59 ? 729  PHE B CB  1 
ATOM   5070  C CG  . PHE A 1 697 ? 200.067 217.566 189.025 1.00 103.59 ? 729  PHE B CG  1 
ATOM   5071  C CD1 . PHE A 1 697 ? 200.446 218.915 188.906 1.00 103.59 ? 729  PHE B CD1 1 
ATOM   5072  C CD2 . PHE A 1 697 ? 201.027 216.599 189.362 1.00 103.59 ? 729  PHE B CD2 1 
ATOM   5073  C CE1 . PHE A 1 697 ? 201.790 219.287 189.073 1.00 103.59 ? 729  PHE B CE1 1 
ATOM   5074  C CE2 . PHE A 1 697 ? 202.367 216.974 189.551 1.00 103.59 ? 729  PHE B CE2 1 
ATOM   5075  C CZ  . PHE A 1 697 ? 202.749 218.318 189.404 1.00 103.59 ? 729  PHE B CZ  1 
ATOM   5076  N N   . GLN A 1 698 ? 195.812 216.028 189.833 1.00 68.44  ? 730  GLN B N   1 
ATOM   5077  C CA  . GLN A 1 698 ? 194.620 215.394 189.326 1.00 68.44  ? 730  GLN B CA  1 
ATOM   5078  C C   . GLN A 1 698 ? 193.353 216.030 189.869 1.00 68.44  ? 730  GLN B C   1 
ATOM   5079  O O   . GLN A 1 698 ? 192.328 215.977 189.191 1.00 68.44  ? 730  GLN B O   1 
ATOM   5080  C CB  . GLN A 1 698 ? 194.664 213.908 189.710 1.00 93.02  ? 730  GLN B CB  1 
ATOM   5081  C CG  . GLN A 1 698 ? 195.809 213.147 189.021 1.00 93.02  ? 730  GLN B CG  1 
ATOM   5082  C CD  . GLN A 1 698 ? 197.220 213.472 189.518 1.00 93.02  ? 730  GLN B CD  1 
ATOM   5083  O OE1 . GLN A 1 698 ? 197.453 213.922 190.633 1.00 93.02  ? 730  GLN B OE1 1 
ATOM   5084  N NE2 . GLN A 1 698 ? 198.229 213.289 188.701 1.00 93.02  ? 730  GLN B NE2 1 
ATOM   5085  N N   . ASP A 1 699 ? 193.385 216.635 191.058 1.00 66.68  ? 731  ASP B N   1 
ATOM   5086  C CA  . ASP A 1 699 ? 192.132 217.075 191.652 1.00 66.68  ? 731  ASP B CA  1 
ATOM   5087  C C   . ASP A 1 699 ? 191.405 218.172 190.887 1.00 66.68  ? 731  ASP B C   1 
ATOM   5088  O O   . ASP A 1 699 ? 190.178 218.134 190.792 1.00 66.68  ? 731  ASP B O   1 
ATOM   5089  C CB  . ASP A 1 699 ? 192.398 217.556 193.080 1.00 84.91  ? 731  ASP B CB  1 
ATOM   5090  C CG  . ASP A 1 699 ? 191.146 217.781 193.896 1.00 84.91  ? 731  ASP B CG  1 
ATOM   5091  O OD1 . ASP A 1 699 ? 190.471 216.813 194.204 1.00 84.91  ? 731  ASP B OD1 1 
ATOM   5092  O OD2 . ASP A 1 699 ? 190.861 218.914 194.243 1.00 84.91  ? 731  ASP B OD2 1 
ATOM   5093  N N   . GLN A 1 700 ? 192.127 219.119 190.300 1.00 69.19  ? 732  GLN B N   1 
ATOM   5094  C CA  . GLN A 1 700 ? 191.444 220.191 189.599 1.00 69.19  ? 732  GLN B CA  1 
ATOM   5095  C C   . GLN A 1 700 ? 191.845 220.282 188.146 1.00 69.19  ? 732  GLN B C   1 
ATOM   5096  O O   . GLN A 1 700 ? 191.979 221.384 187.598 1.00 69.19  ? 732  GLN B O   1 
ATOM   5097  C CB  . GLN A 1 700 ? 191.600 221.543 190.304 1.00 94.04  ? 732  GLN B CB  1 
ATOM   5098  C CG  . GLN A 1 700 ? 191.042 221.575 191.727 1.00 94.04  ? 732  GLN B CG  1 
ATOM   5099  C CD  . GLN A 1 700 ? 189.544 221.380 191.756 1.00 94.04  ? 732  GLN B CD  1 
ATOM   5100  O OE1 . GLN A 1 700 ? 188.797 222.069 191.051 1.00 94.04  ? 732  GLN B OE1 1 
ATOM   5101  N NE2 . GLN A 1 700 ? 189.095 220.427 192.552 1.00 94.04  ? 732  GLN B NE2 1 
ATOM   5102  N N   . ARG A 1 701 ? 192.125 219.149 187.472 1.00 71.67  ? 733  ARG B N   1 
ATOM   5103  C CA  . ARG A 1 701 ? 192.372 219.103 186.006 1.00 71.67  ? 733  ARG B CA  1 
ATOM   5104  C C   . ARG A 1 701 ? 191.061 219.418 185.282 1.00 71.67  ? 733  ARG B C   1 
ATOM   5105  O O   . ARG A 1 701 ? 190.339 218.532 184.831 1.00 71.67  ? 733  ARG B O   1 
ATOM   5106  C CB  . ARG A 1 701 ? 192.983 217.757 185.540 1.00 100.65 ? 733  ARG B CB  1 
ATOM   5107  C CG  . ARG A 1 701 ? 194.472 217.599 185.885 1.00 100.65 ? 733  ARG B CG  1 
ATOM   5108  C CD  . ARG A 1 701 ? 195.490 218.246 184.922 1.00 100.65 ? 733  ARG B CD  1 
ATOM   5109  N NE  . ARG A 1 701 ? 195.973 217.344 183.847 1.00 100.65 ? 733  ARG B NE  1 
ATOM   5110  C CZ  . ARG A 1 701 ? 197.127 217.409 183.191 1.00 100.65 ? 733  ARG B CZ  1 
ATOM   5111  N NH1 . ARG A 1 701 ? 197.431 216.542 182.271 1.00 100.65 ? 733  ARG B NH1 1 
ATOM   5112  N NH2 . ARG A 1 701 ? 198.014 218.330 183.427 1.00 100.65 ? 733  ARG B NH2 1 
ATOM   5113  N N   . THR A 1 702 ? 190.732 220.703 185.245 1.00 76.31  ? 734  THR B N   1 
ATOM   5114  C CA  . THR A 1 702 ? 189.504 221.243 184.720 1.00 76.31  ? 734  THR B CA  1 
ATOM   5115  C C   . THR A 1 702 ? 189.447 221.296 183.217 1.00 76.31  ? 734  THR B C   1 
ATOM   5116  O O   . THR A 1 702 ? 190.423 221.018 182.529 1.00 76.31  ? 734  THR B O   1 
ATOM   5117  C CB  . THR A 1 702 ? 189.279 222.643 185.273 1.00 104.46 ? 734  THR B CB  1 
ATOM   5118  O OG1 . THR A 1 702 ? 187.967 223.086 184.882 1.00 104.46 ? 734  THR B OG1 1 
ATOM   5119  C CG2 . THR A 1 702 ? 190.352 223.586 184.737 1.00 104.46 ? 734  THR B CG2 1 
ATOM   5120  N N   . LEU A 1 703 ? 188.293 221.688 182.704 1.00 77.20  ? 735  LEU B N   1 
ATOM   5121  C CA  . LEU A 1 703 ? 188.073 221.748 181.266 1.00 77.20  ? 735  LEU B CA  1 
ATOM   5122  C C   . LEU A 1 703 ? 188.912 222.803 180.576 1.00 77.20  ? 735  LEU B C   1 
ATOM   5123  O O   . LEU A 1 703 ? 189.284 222.638 179.416 1.00 77.20  ? 735  LEU B O   1 
ATOM   5124  C CB  . LEU A 1 703 ? 186.599 222.011 180.985 1.00 109.73 ? 735  LEU B CB  1 
ATOM   5125  C CG  . LEU A 1 703 ? 185.625 220.880 181.370 1.00 109.73 ? 735  LEU B CG  1 
ATOM   5126  C CD1 . LEU A 1 703 ? 184.209 221.385 181.190 1.00 109.73 ? 735  LEU B CD1 1 
ATOM   5127  C CD2 . LEU A 1 703 ? 185.860 219.641 180.502 1.00 109.73 ? 735  LEU B CD2 1 
ATOM   5128  N N   . ASP A 1 704 ? 189.177 223.901 181.265 1.00 79.52  ? 736  ASP B N   1 
ATOM   5129  C CA  . ASP A 1 704 ? 190.003 224.963 180.728 1.00 79.52  ? 736  ASP B CA  1 
ATOM   5130  C C   . ASP A 1 704 ? 191.310 224.968 181.507 1.00 79.52  ? 736  ASP B C   1 
ATOM   5131  O O   . ASP A 1 704 ? 191.336 225.517 182.613 1.00 79.52  ? 736  ASP B O   1 
ATOM   5132  C CB  . ASP A 1 704 ? 189.309 226.302 180.816 1.00 101.26 ? 736  ASP B CB  1 
ATOM   5133  C CG  . ASP A 1 704 ? 190.156 227.469 180.246 1.00 101.26 ? 736  ASP B CG  1 
ATOM   5134  O OD1 . ASP A 1 704 ? 191.394 227.387 180.146 1.00 101.26 ? 736  ASP B OD1 1 
ATOM   5135  O OD2 . ASP A 1 704 ? 189.546 228.456 179.902 1.00 101.26 ? 736  ASP B OD2 1 
ATOM   5136  N N   . PRO A 1 705 ? 192.389 224.363 180.947 1.00 79.05  ? 737  PRO B N   1 
ATOM   5137  C CA  . PRO A 1 705 ? 193.703 224.160 181.556 1.00 79.05  ? 737  PRO B CA  1 
ATOM   5138  C C   . PRO A 1 705 ? 194.376 225.384 182.144 1.00 79.05  ? 737  PRO B C   1 
ATOM   5139  O O   . PRO A 1 705 ? 195.229 225.241 183.015 1.00 79.05  ? 737  PRO B O   1 
ATOM   5140  C CB  . PRO A 1 705 ? 194.618 223.652 180.444 1.00 135.08 ? 737  PRO B CB  1 
ATOM   5141  C CG  . PRO A 1 705 ? 193.685 222.917 179.514 1.00 135.08 ? 737  PRO B CG  1 
ATOM   5142  C CD  . PRO A 1 705 ? 192.392 223.708 179.647 1.00 135.08 ? 737  PRO B CD  1 
ATOM   5143  N N   . ARG A 1 706 ? 194.023 226.593 181.710 1.00 78.77  ? 738  ARG B N   1 
ATOM   5144  C CA  . ARG A 1 706 ? 194.571 227.807 182.327 1.00 78.77  ? 738  ARG B CA  1 
ATOM   5145  C C   . ARG A 1 706 ? 194.184 227.893 183.792 1.00 78.77  ? 738  ARG B C   1 
ATOM   5146  O O   . ARG A 1 706 ? 194.897 228.499 184.590 1.00 78.77  ? 738  ARG B O   1 
ATOM   5147  C CB  . ARG A 1 706 ? 194.023 229.029 181.601 1.00 110.63 ? 738  ARG B CB  1 
ATOM   5148  C CG  . ARG A 1 706 ? 194.379 229.024 180.109 1.00 110.63 ? 738  ARG B CG  1 
ATOM   5149  C CD  . ARG A 1 706 ? 193.738 230.221 179.410 1.00 110.63 ? 738  ARG B CD  1 
ATOM   5150  N NE  . ARG A 1 706 ? 192.264 230.144 179.426 1.00 110.63 ? 738  ARG B NE  1 
ATOM   5151  C CZ  . ARG A 1 706 ? 191.446 231.143 179.148 1.00 110.63 ? 738  ARG B CZ  1 
ATOM   5152  N NH1 . ARG A 1 706 ? 190.161 230.972 179.155 1.00 110.63 ? 738  ARG B NH1 1 
ATOM   5153  N NH2 . ARG A 1 706 ? 191.881 232.333 178.856 1.00 110.63 ? 738  ARG B NH2 1 
ATOM   5154  N N   . PHE A 1 707 ? 193.077 227.246 184.153 1.00 79.56  ? 739  PHE B N   1 
ATOM   5155  C CA  . PHE A 1 707 ? 192.531 227.287 185.475 1.00 79.56  ? 739  PHE B CA  1 
ATOM   5156  C C   . PHE A 1 707 ? 192.755 225.973 186.170 1.00 79.56  ? 739  PHE B C   1 
ATOM   5157  O O   . PHE A 1 707 ? 192.139 225.698 187.202 1.00 79.56  ? 739  PHE B O   1 
ATOM   5158  C CB  . PHE A 1 707 ? 191.072 227.624 185.378 1.00 107.59 ? 739  PHE B CB  1 
ATOM   5159  C CG  . PHE A 1 707 ? 190.946 228.895 184.690 1.00 107.59 ? 739  PHE B CG  1 
ATOM   5160  C CD1 . PHE A 1 707 ? 191.247 230.088 185.311 1.00 107.59 ? 739  PHE B CD1 1 
ATOM   5161  C CD2 . PHE A 1 707 ? 190.572 228.904 183.382 1.00 107.59 ? 739  PHE B CD2 1 
ATOM   5162  C CE1 . PHE A 1 707 ? 191.163 231.266 184.613 1.00 107.59 ? 739  PHE B CE1 1 
ATOM   5163  C CE2 . PHE A 1 707 ? 190.481 230.065 182.680 1.00 107.59 ? 739  PHE B CE2 1 
ATOM   5164  C CZ  . PHE A 1 707 ? 190.777 231.252 183.288 1.00 107.59 ? 739  PHE B CZ  1 
ATOM   5165  N N   . ALA A 1 708 ? 193.599 225.129 185.582 1.00 82.83  ? 740  ALA B N   1 
ATOM   5166  C CA  . ALA A 1 708 ? 193.909 223.876 186.214 1.00 82.83  ? 740  ALA B CA  1 
ATOM   5167  C C   . ALA A 1 708 ? 194.741 224.210 187.403 1.00 82.83  ? 740  ALA B C   1 
ATOM   5168  O O   . ALA A 1 708 ? 195.670 225.021 187.309 1.00 82.83  ? 740  ALA B O   1 
ATOM   5169  C CB  . ALA A 1 708 ? 194.645 222.942 185.278 1.00 111.90 ? 740  ALA B CB  1 
ATOM   5170  N N   . ARG A 1 709 ? 194.479 223.536 188.495 1.00 82.14  ? 741  ARG B N   1 
ATOM   5171  C CA  . ARG A 1 709 ? 195.272 223.790 189.684 1.00 82.14  ? 741  ARG B CA  1 
ATOM   5172  C C   . ARG A 1 709 ? 195.693 222.525 190.372 1.00 82.14  ? 741  ARG B C   1 
ATOM   5173  O O   . ARG A 1 709 ? 194.919 221.582 190.504 1.00 82.14  ? 741  ARG B O   1 
ATOM   5174  C CB  . ARG A 1 709 ? 194.507 224.668 190.660 1.00 115.36 ? 741  ARG B CB  1 
ATOM   5175  C CG  . ARG A 1 709 ? 194.199 226.085 190.158 1.00 115.36 ? 741  ARG B CG  1 
ATOM   5176  C CD  . ARG A 1 709 ? 195.431 226.917 190.076 1.00 115.36 ? 741  ARG B CD  1 
ATOM   5177  N NE  . ARG A 1 709 ? 195.147 228.283 189.668 1.00 115.36 ? 741  ARG B NE  1 
ATOM   5178  C CZ  . ARG A 1 709 ? 195.079 228.725 188.384 1.00 115.36 ? 741  ARG B CZ  1 
ATOM   5179  N NH1 . ARG A 1 709 ? 194.803 230.004 188.153 1.00 115.36 ? 741  ARG B NH1 1 
ATOM   5180  N NH2 . ARG A 1 709 ? 195.289 227.916 187.367 1.00 115.36 ? 741  ARG B NH2 1 
ATOM   5181  N N   . GLY A 1 710 ? 196.935 222.496 190.801 1.00 83.26  ? 742  GLY B N   1 
ATOM   5182  C CA  . GLY A 1 710 ? 197.375 221.354 191.550 1.00 83.26  ? 742  GLY B CA  1 
ATOM   5183  C C   . GLY A 1 710 ? 197.417 221.790 192.983 1.00 83.26  ? 742  GLY B C   1 
ATOM   5184  O O   . GLY A 1 710 ? 197.178 222.963 193.265 1.00 83.26  ? 742  GLY B O   1 
ATOM   5185  N N   . VAL A 1 711 ? 197.712 220.874 193.880 1.00 84.42  ? 743  VAL B N   1 
ATOM   5186  C CA  . VAL A 1 711 ? 197.787 221.197 195.292 1.00 84.42  ? 743  VAL B CA  1 
ATOM   5187  C C   . VAL A 1 711 ? 199.022 220.630 195.970 1.00 84.42  ? 743  VAL B C   1 
ATOM   5188  O O   . VAL A 1 711 ? 199.311 219.440 195.850 1.00 84.42  ? 743  VAL B O   1 
ATOM   5189  C CB  . VAL A 1 711 ? 196.534 220.672 196.040 1.00 118.88 ? 743  VAL B CB  1 
ATOM   5190  C CG1 . VAL A 1 711 ? 196.628 221.019 197.508 1.00 118.88 ? 743  VAL B CG1 1 
ATOM   5191  C CG2 . VAL A 1 711 ? 195.261 221.256 195.440 1.00 118.88 ? 743  VAL B CG2 1 
ATOM   5192  N N   . LEU A 1 712 ? 199.704 221.453 196.751 1.00 86.73  ? 744  LEU B N   1 
ATOM   5193  C CA  . LEU A 1 712 ? 200.811 220.966 197.546 1.00 86.73  ? 744  LEU B CA  1 
ATOM   5194  C C   . LEU A 1 712 ? 200.222 220.612 198.890 1.00 86.73  ? 744  LEU B C   1 
ATOM   5195  O O   . LEU A 1 712 ? 199.736 221.469 199.635 1.00 86.73  ? 744  LEU B O   1 
ATOM   5196  C CB  . LEU A 1 712 ? 201.903 222.013 197.739 1.00 123.27 ? 744  LEU B CB  1 
ATOM   5197  C CG  . LEU A 1 712 ? 203.096 221.588 198.648 1.00 123.27 ? 744  LEU B CG  1 
ATOM   5198  C CD1 . LEU A 1 712 ? 203.873 220.428 198.033 1.00 123.27 ? 744  LEU B CD1 1 
ATOM   5199  C CD2 . LEU A 1 712 ? 203.988 222.788 198.875 1.00 123.27 ? 744  LEU B CD2 1 
ATOM   5200  N N   . LYS A 1 713 ? 200.246 219.339 199.189 1.00 85.10  ? 745  LYS B N   1 
ATOM   5201  C CA  . LYS A 1 713 ? 199.606 218.827 200.381 1.00 85.10  ? 745  LYS B CA  1 
ATOM   5202  C C   . LYS A 1 713 ? 200.468 217.769 201.037 1.00 85.10  ? 745  LYS B C   1 
ATOM   5203  O O   . LYS A 1 713 ? 201.369 217.232 200.383 1.00 85.10  ? 745  LYS B O   1 
ATOM   5204  C CB  . LYS A 1 713 ? 198.239 218.225 200.007 1.00 121.73 ? 745  LYS B CB  1 
ATOM   5205  C CG  . LYS A 1 713 ? 198.331 216.973 199.130 1.00 121.73 ? 745  LYS B CG  1 
ATOM   5206  C CD  . LYS A 1 713 ? 196.964 216.494 198.662 1.00 121.73 ? 745  LYS B CD  1 
ATOM   5207  C CE  . LYS A 1 713 ? 197.063 215.090 198.056 1.00 121.73 ? 745  LYS B CE  1 
ATOM   5208  N NZ  . LYS A 1 713 ? 195.763 214.624 197.440 1.00 121.73 ? 745  LYS B NZ  1 
ATOM   5209  N N   . CYS A 1 714 ? 200.212 217.483 202.338 1.00 88.07  ? 746  CYS B N   1 
ATOM   5210  C CA  . CYS A 1 714 ? 200.812 216.339 203.009 1.00 88.07  ? 746  CYS B CA  1 
ATOM   5211  C C   . CYS A 1 714 ? 199.960 215.150 202.546 1.00 88.07  ? 746  CYS B C   1 
ATOM   5212  O O   . CYS A 1 714 ? 198.717 215.169 202.610 1.00 88.07  ? 746  CYS B O   1 
ATOM   5213  C CB  . CYS A 1 714 ? 200.844 216.447 204.544 1.00 114.13 ? 746  CYS B CB  1 
ATOM   5214  S SG  . CYS A 1 714 ? 201.669 215.021 205.274 1.00 114.13 ? 746  CYS B SG  1 
ATOM   5215  N N   . ASP A 1 715 ? 200.616 214.108 202.086 1.00 84.21  ? 747  ASP B N   1 
ATOM   5216  C CA  . ASP A 1 715 ? 199.892 212.988 201.530 1.00 84.21  ? 747  ASP B CA  1 
ATOM   5217  C C   . ASP A 1 715 ? 199.371 212.060 202.606 1.00 84.21  ? 747  ASP B C   1 
ATOM   5218  O O   . ASP A 1 715 ? 199.899 210.967 202.819 1.00 84.21  ? 747  ASP B O   1 
ATOM   5219  C CB  . ASP A 1 715 ? 200.806 212.175 200.613 1.00 107.23 ? 747  ASP B CB  1 
ATOM   5220  C CG  . ASP A 1 715 ? 200.052 211.192 199.726 1.00 107.23 ? 747  ASP B CG  1 
ATOM   5221  O OD1 . ASP A 1 715 ? 198.842 211.299 199.658 1.00 107.23 ? 747  ASP B OD1 1 
ATOM   5222  O OD2 . ASP A 1 715 ? 200.683 210.376 199.083 1.00 107.23 ? 747  ASP B OD2 1 
ATOM   5223  N N   . ILE A 1 716 ? 198.347 212.490 203.309 1.00 81.82  ? 748  ILE B N   1 
ATOM   5224  C CA  . ILE A 1 716 ? 197.837 211.614 204.327 1.00 81.82  ? 748  ILE B CA  1 
ATOM   5225  C C   . ILE A 1 716 ? 196.551 211.063 203.769 1.00 81.82  ? 748  ILE B C   1 
ATOM   5226  O O   . ILE A 1 716 ? 195.588 211.793 203.530 1.00 81.82  ? 748  ILE B O   1 
ATOM   5227  C CB  . ILE A 1 716 ? 197.590 212.308 205.665 1.00 116.29 ? 748  ILE B CB  1 
ATOM   5228  C CG1 . ILE A 1 716 ? 198.880 212.985 206.129 1.00 116.29 ? 748  ILE B CG1 1 
ATOM   5229  C CG2 . ILE A 1 716 ? 197.217 211.192 206.706 1.00 116.29 ? 748  ILE B CG2 1 
ATOM   5230  C CD1 . ILE A 1 716 ? 198.741 213.919 207.340 1.00 116.29 ? 748  ILE B CD1 1 
ATOM   5231  N N   . SER A 1 717 ? 196.563 209.771 203.546 1.00 82.59  ? 749  SER B N   1 
ATOM   5232  C CA  . SER A 1 717 ? 195.448 209.054 202.982 1.00 82.59  ? 749  SER B CA  1 
ATOM   5233  C C   . SER A 1 717 ? 194.301 209.140 203.926 1.00 82.59  ? 749  SER B C   1 
ATOM   5234  O O   . SER A 1 717 ? 194.512 209.160 205.138 1.00 82.59  ? 749  SER B O   1 
ATOM   5235  C CB  . SER A 1 717 ? 195.802 207.605 202.762 1.00 110.01 ? 749  SER B CB  1 
ATOM   5236  O OG  . SER A 1 717 ? 194.676 206.869 202.353 1.00 110.01 ? 749  SER B OG  1 
ATOM   5237  N N   . ASP A 1 718 ? 193.088 209.153 203.408 1.00 81.71  ? 750  ASP B N   1 
ATOM   5238  C CA  . ASP A 1 718 ? 191.944 209.197 204.273 1.00 81.71  ? 750  ASP B CA  1 
ATOM   5239  C C   . ASP A 1 718 ? 191.846 207.939 205.100 1.00 81.71  ? 750  ASP B C   1 
ATOM   5240  O O   . ASP A 1 718 ? 191.221 207.932 206.161 1.00 81.71  ? 750  ASP B O   1 
ATOM   5241  C CB  . ASP A 1 718 ? 190.706 209.418 203.440 1.00 104.05 ? 750  ASP B CB  1 
ATOM   5242  C CG  . ASP A 1 718 ? 190.635 208.383 202.380 1.00 104.05 ? 750  ASP B CG  1 
ATOM   5243  O OD1 . ASP A 1 718 ? 191.563 208.364 201.578 1.00 104.05 ? 750  ASP B OD1 1 
ATOM   5244  O OD2 . ASP A 1 718 ? 189.704 207.623 202.343 1.00 104.05 ? 750  ASP B OD2 1 
ATOM   5245  N N   . LEU A 1 719 ? 192.489 206.861 204.665 1.00 81.87  ? 751  LEU B N   1 
ATOM   5246  C CA  . LEU A 1 719 ? 192.432 205.678 205.478 1.00 81.87  ? 751  LEU B CA  1 
ATOM   5247  C C   . LEU A 1 719 ? 193.100 205.947 206.806 1.00 81.87  ? 751  LEU B C   1 
ATOM   5248  O O   . LEU A 1 719 ? 192.533 205.621 207.851 1.00 81.87  ? 751  LEU B O   1 
ATOM   5249  C CB  . LEU A 1 719 ? 193.122 204.502 204.781 1.00 116.37 ? 751  LEU B CB  1 
ATOM   5250  C CG  . LEU A 1 719 ? 193.224 203.173 205.588 1.00 116.37 ? 751  LEU B CG  1 
ATOM   5251  C CD1 . LEU A 1 719 ? 191.847 202.640 205.955 1.00 116.37 ? 751  LEU B CD1 1 
ATOM   5252  C CD2 . LEU A 1 719 ? 193.980 202.156 204.745 1.00 116.37 ? 751  LEU B CD2 1 
ATOM   5253  N N   . SER A 1 720 ? 194.289 206.554 206.781 1.00 81.67  ? 752  SER B N   1 
ATOM   5254  C CA  . SER A 1 720 ? 194.981 206.834 208.014 1.00 81.67  ? 752  SER B CA  1 
ATOM   5255  C C   . SER A 1 720 ? 194.457 208.108 208.639 1.00 81.67  ? 752  SER B C   1 
ATOM   5256  O O   . SER A 1 720 ? 194.427 208.229 209.858 1.00 81.67  ? 752  SER B O   1 
ATOM   5257  C CB  . SER A 1 720 ? 196.477 206.909 207.806 1.00 108.78 ? 752  SER B CB  1 
ATOM   5258  O OG  . SER A 1 720 ? 196.831 207.994 207.019 1.00 108.78 ? 752  SER B OG  1 
ATOM   5259  N N   . LEU A 1 721 ? 193.872 209.023 207.860 1.00 83.65  ? 753  LEU B N   1 
ATOM   5260  C CA  . LEU A 1 721 ? 193.362 210.199 208.541 1.00 83.65  ? 753  LEU B CA  1 
ATOM   5261  C C   . LEU A 1 721 ? 192.318 209.727 209.505 1.00 83.65  ? 753  LEU B C   1 
ATOM   5262  O O   . LEU A 1 721 ? 192.261 210.196 210.633 1.00 83.65  ? 753  LEU B O   1 
ATOM   5263  C CB  . LEU A 1 721 ? 192.709 211.234 207.602 1.00 118.90 ? 753  LEU B CB  1 
ATOM   5264  C CG  . LEU A 1 721 ? 193.627 212.048 206.671 1.00 118.90 ? 753  LEU B CG  1 
ATOM   5265  C CD1 . LEU A 1 721 ? 192.816 212.822 205.669 1.00 118.90 ? 753  LEU B CD1 1 
ATOM   5266  C CD2 . LEU A 1 721 ? 194.427 213.037 207.516 1.00 118.90 ? 753  LEU B CD2 1 
ATOM   5267  N N   . ILE A 1 722 ? 191.532 208.746 209.094 1.00 84.82  ? 754  ILE B N   1 
ATOM   5268  C CA  . ILE A 1 722 ? 190.538 208.238 209.983 1.00 84.82  ? 754  ILE B CA  1 
ATOM   5269  C C   . ILE A 1 722 ? 191.110 207.230 210.967 1.00 84.82  ? 754  ILE B C   1 
ATOM   5270  O O   . ILE A 1 722 ? 190.813 207.313 212.152 1.00 84.82  ? 754  ILE B O   1 
ATOM   5271  C CB  . ILE A 1 722 ? 189.370 207.632 209.204 1.00 120.56 ? 754  ILE B CB  1 
ATOM   5272  C CG1 . ILE A 1 722 ? 188.737 208.729 208.254 1.00 120.56 ? 754  ILE B CG1 1 
ATOM   5273  C CG2 . ILE A 1 722 ? 188.318 207.047 210.175 1.00 120.56 ? 754  ILE B CG2 1 
ATOM   5274  C CD1 . ILE A 1 722 ? 188.253 210.013 208.909 1.00 120.56 ? 754  ILE B CD1 1 
ATOM   5275  N N   . CYS A 1 723 ? 191.942 206.287 210.544 1.00 84.50  ? 755  CYS B N   1 
ATOM   5276  C CA  . CYS A 1 723 ? 192.408 205.287 211.499 1.00 84.50  ? 755  CYS B CA  1 
ATOM   5277  C C   . CYS A 1 723 ? 193.239 205.891 212.645 1.00 84.50  ? 755  CYS B C   1 
ATOM   5278  O O   . CYS A 1 723 ? 193.199 205.392 213.783 1.00 84.50  ? 755  CYS B O   1 
ATOM   5279  C CB  . CYS A 1 723 ? 193.204 204.208 210.788 1.00 112.55 ? 755  CYS B CB  1 
ATOM   5280  S SG  . CYS A 1 723 ? 192.200 203.205 209.658 1.00 112.55 ? 755  CYS B SG  1 
ATOM   5281  N N   . LEU A 1 724 ? 193.920 207.010 212.379 1.00 84.37  ? 756  LEU B N   1 
ATOM   5282  C CA  . LEU A 1 724 ? 194.730 207.710 213.367 1.00 84.37  ? 756  LEU B CA  1 
ATOM   5283  C C   . LEU A 1 724 ? 193.859 208.392 214.410 1.00 84.37  ? 756  LEU B C   1 
ATOM   5284  O O   . LEU A 1 724 ? 194.350 208.788 215.465 1.00 84.37  ? 756  LEU B O   1 
ATOM   5285  C CB  . LEU A 1 724 ? 195.593 208.782 212.681 1.00 119.92 ? 756  LEU B CB  1 
ATOM   5286  C CG  . LEU A 1 724 ? 196.742 208.294 211.715 1.00 119.92 ? 756  LEU B CG  1 
ATOM   5287  C CD1 . LEU A 1 724 ? 197.311 209.512 210.954 1.00 119.92 ? 756  LEU B CD1 1 
ATOM   5288  C CD2 . LEU A 1 724 ? 197.847 207.643 212.492 1.00 119.92 ? 756  LEU B CD2 1 
ATOM   5289  N N   . LEU A 1 725 ? 192.592 208.585 214.079 1.00 88.47  ? 757  LEU B N   1 
ATOM   5290  C CA  . LEU A 1 725 ? 191.605 209.202 214.929 1.00 88.47  ? 757  LEU B CA  1 
ATOM   5291  C C   . LEU A 1 725 ? 190.717 208.117 215.526 1.00 88.47  ? 757  LEU B C   1 
ATOM   5292  O O   . LEU A 1 725 ? 190.187 208.286 216.617 1.00 88.47  ? 757  LEU B O   1 
ATOM   5293  C CB  . LEU A 1 725 ? 190.815 210.187 214.085 1.00 125.75 ? 757  LEU B CB  1 
ATOM   5294  C CG  . LEU A 1 725 ? 191.667 211.326 213.456 1.00 125.75 ? 757  LEU B CG  1 
ATOM   5295  C CD1 . LEU A 1 725 ? 190.797 212.109 212.477 1.00 125.75 ? 757  LEU B CD1 1 
ATOM   5296  C CD2 . LEU A 1 725 ? 192.219 212.272 214.562 1.00 125.75 ? 757  LEU B CD2 1 
ATOM   5297  N N   . GLY A 1 726 ? 190.573 207.002 214.809 1.00 89.83  ? 758  GLY B N   1 
ATOM   5298  C CA  . GLY A 1 726 ? 189.745 205.865 215.183 1.00 89.83  ? 758  GLY B CA  1 
ATOM   5299  C C   . GLY A 1 726 ? 190.185 205.277 216.508 1.00 89.83  ? 758  GLY B C   1 
ATOM   5300  O O   . GLY A 1 726 ? 189.384 205.130 217.423 1.00 89.83  ? 758  GLY B O   1 
ATOM   5301  N N   . TYR A 1 727 ? 191.467 204.967 216.647 1.00 92.09  ? 759  TYR B N   1 
ATOM   5302  C CA  . TYR A 1 727 ? 191.910 204.425 217.935 1.00 92.09  ? 759  TYR B CA  1 
ATOM   5303  C C   . TYR A 1 727 ? 191.520 205.374 219.055 1.00 92.09  ? 759  TYR B C   1 
ATOM   5304  O O   . TYR A 1 727 ? 191.045 204.962 220.121 1.00 92.09  ? 759  TYR B O   1 
ATOM   5305  C CB  . TYR A 1 727 ? 193.417 204.206 217.992 1.00 123.61 ? 759  TYR B CB  1 
ATOM   5306  C CG  . TYR A 1 727 ? 193.900 203.672 219.361 1.00 123.61 ? 759  TYR B CG  1 
ATOM   5307  C CD1 . TYR A 1 727 ? 193.872 202.313 219.629 1.00 123.61 ? 759  TYR B CD1 1 
ATOM   5308  C CD2 . TYR A 1 727 ? 194.347 204.543 220.346 1.00 123.61 ? 759  TYR B CD2 1 
ATOM   5309  C CE1 . TYR A 1 727 ? 194.297 201.835 220.865 1.00 123.61 ? 759  TYR B CE1 1 
ATOM   5310  C CE2 . TYR A 1 727 ? 194.768 204.053 221.572 1.00 123.61 ? 759  TYR B CE2 1 
ATOM   5311  C CZ  . TYR A 1 727 ? 194.744 202.720 221.831 1.00 123.61 ? 759  TYR B CZ  1 
ATOM   5312  O OH  . TYR A 1 727 ? 195.157 202.254 223.054 1.00 123.61 ? 759  TYR B OH  1 
ATOM   5313  N N   . SER A 1 728 ? 191.785 206.654 218.829 1.00 91.52  ? 760  SER B N   1 
ATOM   5314  C CA  . SER A 1 728 ? 191.536 207.660 219.825 1.00 91.52  ? 760  SER B CA  1 
ATOM   5315  C C   . SER A 1 728 ? 190.045 207.689 220.128 1.00 91.52  ? 760  SER B C   1 
ATOM   5316  O O   . SER A 1 728 ? 189.645 207.713 221.292 1.00 91.52  ? 760  SER B O   1 
ATOM   5317  C CB  . SER A 1 728 ? 191.940 209.004 219.282 1.00 121.90 ? 760  SER B CB  1 
ATOM   5318  O OG  . SER A 1 728 ? 193.298 209.085 218.971 1.00 121.90 ? 760  SER B OG  1 
ATOM   5319  N N   . MET A 1 729 ? 189.224 207.573 219.086 1.00 90.34  ? 761  MET B N   1 
ATOM   5320  C CA  . MET A 1 729 ? 187.786 207.532 219.223 1.00 90.34  ? 761  MET B CA  1 
ATOM   5321  C C   . MET A 1 729 ? 187.404 206.383 220.110 1.00 90.34  ? 761  MET B C   1 
ATOM   5322  O O   . MET A 1 729 ? 186.548 206.516 220.960 1.00 90.34  ? 761  MET B O   1 
ATOM   5323  C CB  . MET A 1 729 ? 187.102 207.339 217.886 1.00 125.68 ? 761  MET B CB  1 
ATOM   5324  C CG  . MET A 1 729 ? 185.587 207.265 217.953 1.00 125.68 ? 761  MET B CG  1 
ATOM   5325  S SD  . MET A 1 729 ? 184.858 206.670 216.440 1.00 125.68 ? 761  MET B SD  1 
ATOM   5326  C CE  . MET A 1 729 ? 185.287 204.907 216.552 1.00 125.68 ? 761  MET B CE  1 
ATOM   5327  N N   . LEU A 1 730 ? 188.036 205.251 219.952 1.00 93.67  ? 762  LEU B N   1 
ATOM   5328  C CA  . LEU A 1 730 ? 187.668 204.126 220.770 1.00 93.67  ? 762  LEU B CA  1 
ATOM   5329  C C   . LEU A 1 730 ? 187.959 204.408 222.239 1.00 93.67  ? 762  LEU B C   1 
ATOM   5330  O O   . LEU A 1 730 ? 187.225 203.933 223.122 1.00 93.67  ? 762  LEU B O   1 
ATOM   5331  C CB  . LEU A 1 730 ? 188.393 202.890 220.271 1.00 133.14 ? 762  LEU B CB  1 
ATOM   5332  C CG  . LEU A 1 730 ? 187.962 202.412 218.856 1.00 133.14 ? 762  LEU B CG  1 
ATOM   5333  C CD1 . LEU A 1 730 ? 188.894 201.310 218.408 1.00 133.14 ? 762  LEU B CD1 1 
ATOM   5334  C CD2 . LEU A 1 730 ? 186.508 201.920 218.859 1.00 133.14 ? 762  LEU B CD2 1 
ATOM   5335  N N   . LEU A 1 731 ? 189.009 205.181 222.523 1.00 94.69  ? 763  LEU B N   1 
ATOM   5336  C CA  . LEU A 1 731 ? 189.292 205.530 223.907 1.00 94.69  ? 763  LEU B CA  1 
ATOM   5337  C C   . LEU A 1 731 ? 188.164 206.446 224.385 1.00 94.69  ? 763  LEU B C   1 
ATOM   5338  O O   . LEU A 1 731 ? 187.711 206.347 225.524 1.00 94.69  ? 763  LEU B O   1 
ATOM   5339  C CB  . LEU A 1 731 ? 190.602 206.307 224.042 1.00 134.59 ? 763  LEU B CB  1 
ATOM   5340  C CG  . LEU A 1 731 ? 191.924 205.619 223.691 1.00 134.59 ? 763  LEU B CG  1 
ATOM   5341  C CD1 . LEU A 1 731 ? 192.999 206.691 223.767 1.00 134.59 ? 763  LEU B CD1 1 
ATOM   5342  C CD2 . LEU A 1 731 ? 192.253 204.472 224.633 1.00 134.59 ? 763  LEU B CD2 1 
ATOM   5343  N N   . MET A 1 732 ? 187.710 207.331 223.494 1.00 92.87  ? 764  MET B N   1 
ATOM   5344  C CA  . MET A 1 732 ? 186.614 208.268 223.747 1.00 92.87  ? 764  MET B CA  1 
ATOM   5345  C C   . MET A 1 732 ? 185.330 207.503 224.031 1.00 92.87  ? 764  MET B C   1 
ATOM   5346  O O   . MET A 1 732 ? 184.545 207.867 224.917 1.00 92.87  ? 764  MET B O   1 
ATOM   5347  C CB  . MET A 1 732 ? 186.394 209.162 222.537 1.00 129.20 ? 764  MET B CB  1 
ATOM   5348  C CG  . MET A 1 732 ? 185.337 210.206 222.665 1.00 129.20 ? 764  MET B CG  1 
ATOM   5349  S SD  . MET A 1 732 ? 184.998 210.977 221.129 1.00 129.20 ? 764  MET B SD  1 
ATOM   5350  C CE  . MET A 1 732 ? 183.915 209.742 220.406 1.00 129.20 ? 764  MET B CE  1 
ATOM   5351  N N   . VAL A 1 733 ? 185.110 206.443 223.270 1.00 93.37  ? 765  VAL B N   1 
ATOM   5352  C CA  . VAL A 1 733 ? 183.946 205.608 223.436 1.00 93.37  ? 765  VAL B CA  1 
ATOM   5353  C C   . VAL A 1 733 ? 184.028 204.938 224.775 1.00 93.37  ? 765  VAL B C   1 
ATOM   5354  O O   . VAL A 1 733 ? 183.033 204.860 225.491 1.00 93.37  ? 765  VAL B O   1 
ATOM   5355  C CB  . VAL A 1 733 ? 183.833 204.560 222.321 1.00 131.49 ? 765  VAL B CB  1 
ATOM   5356  C CG1 . VAL A 1 733 ? 182.715 203.559 222.637 1.00 131.49 ? 765  VAL B CG1 1 
ATOM   5357  C CG2 . VAL A 1 733 ? 183.530 205.270 221.006 1.00 131.49 ? 765  VAL B CG2 1 
ATOM   5358  N N   . THR A 1 734 ? 185.206 204.454 225.115 1.00 94.39  ? 766  THR B N   1 
ATOM   5359  C CA  . THR A 1 734 ? 185.409 203.797 226.375 1.00 94.39  ? 766  THR B CA  1 
ATOM   5360  C C   . THR A 1 734 ? 185.157 204.798 227.506 1.00 94.39  ? 766  THR B C   1 
ATOM   5361  O O   . THR A 1 734 ? 184.525 204.450 228.503 1.00 94.39  ? 766  THR B O   1 
ATOM   5362  C CB  . THR A 1 734 ? 186.812 203.193 226.449 1.00 129.21 ? 766  THR B CB  1 
ATOM   5363  O OG1 . THR A 1 734 ? 186.991 202.260 225.372 1.00 129.21 ? 766  THR B OG1 1 
ATOM   5364  C CG2 . THR A 1 734 ? 186.928 202.441 227.754 1.00 129.21 ? 766  THR B CG2 1 
ATOM   5365  N N   . CYS A 1 735 ? 185.615 206.048 227.338 1.00 93.82  ? 767  CYS B N   1 
ATOM   5366  C CA  . CYS A 1 735 ? 185.417 207.091 228.339 1.00 93.82  ? 767  CYS B CA  1 
ATOM   5367  C C   . CYS A 1 735 ? 183.939 207.313 228.535 1.00 93.82  ? 767  CYS B C   1 
ATOM   5368  O O   . CYS A 1 735 ? 183.480 207.466 229.669 1.00 93.82  ? 767  CYS B O   1 
ATOM   5369  C CB  . CYS A 1 735 ? 185.987 208.444 227.890 1.00 124.97 ? 767  CYS B CB  1 
ATOM   5370  S SG  . CYS A 1 735 ? 187.734 208.591 227.775 1.00 124.97 ? 767  CYS B SG  1 
ATOM   5371  N N   . THR A 1 736 ? 183.191 207.313 227.427 1.00 92.64  ? 768  THR B N   1 
ATOM   5372  C CA  . THR A 1 736 ? 181.756 207.510 227.469 1.00 92.64  ? 768  THR B CA  1 
ATOM   5373  C C   . THR A 1 736 ? 181.146 206.369 228.264 1.00 92.64  ? 768  THR B C   1 
ATOM   5374  O O   . THR A 1 736 ? 180.310 206.595 229.139 1.00 92.64  ? 768  THR B O   1 
ATOM   5375  C CB  . THR A 1 736 ? 181.152 207.568 226.049 1.00 126.81 ? 768  THR B CB  1 
ATOM   5376  O OG1 . THR A 1 736 ? 181.738 208.664 225.320 1.00 126.81 ? 768  THR B OG1 1 
ATOM   5377  C CG2 . THR A 1 736 ? 179.652 207.791 226.144 1.00 126.81 ? 768  THR B CG2 1 
ATOM   5378  N N   . VAL A 1 737 ? 181.600 205.152 228.005 1.00 93.02  ? 769  VAL B N   1 
ATOM   5379  C CA  . VAL A 1 737 ? 181.092 204.016 228.732 1.00 93.02  ? 769  VAL B CA  1 
ATOM   5380  C C   . VAL A 1 737 ? 181.395 204.136 230.202 1.00 93.02  ? 769  VAL B C   1 
ATOM   5381  O O   . VAL A 1 737 ? 180.537 203.811 231.023 1.00 93.02  ? 769  VAL B O   1 
ATOM   5382  C CB  . VAL A 1 737 ? 181.648 202.705 228.180 1.00 130.99 ? 769  VAL B CB  1 
ATOM   5383  C CG1 . VAL A 1 737 ? 181.283 201.551 229.105 1.00 130.99 ? 769  VAL B CG1 1 
ATOM   5384  C CG2 . VAL A 1 737 ? 181.057 202.476 226.798 1.00 130.99 ? 769  VAL B CG2 1 
ATOM   5385  N N   . TYR A 1 738 ? 182.595 204.565 230.560 1.00 90.71  ? 770  TYR B N   1 
ATOM   5386  C CA  . TYR A 1 738 ? 182.880 204.703 231.966 1.00 90.71  ? 770  TYR B CA  1 
ATOM   5387  C C   . TYR A 1 738 ? 181.964 205.753 232.555 1.00 90.71  ? 770  TYR B C   1 
ATOM   5388  O O   . TYR A 1 738 ? 181.410 205.555 233.633 1.00 90.71  ? 770  TYR B O   1 
ATOM   5389  C CB  . TYR A 1 738 ? 184.316 205.096 232.218 1.00 121.76 ? 770  TYR B CB  1 
ATOM   5390  C CG  . TYR A 1 738 ? 185.333 204.100 231.865 1.00 121.76 ? 770  TYR B CG  1 
ATOM   5391  C CD1 . TYR A 1 738 ? 185.003 202.797 231.518 1.00 121.76 ? 770  TYR B CD1 1 
ATOM   5392  C CD2 . TYR A 1 738 ? 186.643 204.473 231.931 1.00 121.76 ? 770  TYR B CD2 1 
ATOM   5393  C CE1 . TYR A 1 738 ? 185.989 201.912 231.237 1.00 121.76 ? 770  TYR B CE1 1 
ATOM   5394  C CE2 . TYR A 1 738 ? 187.616 203.578 231.655 1.00 121.76 ? 770  TYR B CE2 1 
ATOM   5395  C CZ  . TYR A 1 738 ? 187.298 202.303 231.307 1.00 121.76 ? 770  TYR B CZ  1 
ATOM   5396  O OH  . TYR A 1 738 ? 188.285 201.392 231.022 1.00 121.76 ? 770  TYR B OH  1 
ATOM   5397  N N   . ALA A 1 739 ? 181.719 206.845 231.822 1.00 88.58  ? 771  ALA B N   1 
ATOM   5398  C CA  . ALA A 1 739 ? 180.851 207.902 232.324 1.00 88.58  ? 771  ALA B CA  1 
ATOM   5399  C C   . ALA A 1 739 ? 179.454 207.348 232.649 1.00 88.58  ? 771  ALA B C   1 
ATOM   5400  O O   . ALA A 1 739 ? 178.822 207.770 233.637 1.00 88.58  ? 771  ALA B O   1 
ATOM   5401  C CB  . ALA A 1 739 ? 180.746 209.036 231.314 1.00 119.67 ? 771  ALA B CB  1 
ATOM   5402  N N   . ILE A 1 740 ? 178.999 206.391 231.824 1.00 89.32  ? 772  ILE B N   1 
ATOM   5403  C CA  . ILE A 1 740 ? 177.725 205.707 231.996 1.00 89.32  ? 772  ILE B CA  1 
ATOM   5404  C C   . ILE A 1 740 ? 177.793 204.807 233.234 1.00 89.32  ? 772  ILE B C   1 
ATOM   5405  O O   . ILE A 1 740 ? 176.882 204.812 234.070 1.00 89.32  ? 772  ILE B O   1 
ATOM   5406  C CB  . ILE A 1 740 ? 177.353 204.884 230.740 1.00 126.95 ? 772  ILE B CB  1 
ATOM   5407  C CG1 . ILE A 1 740 ? 177.075 205.853 229.555 1.00 126.95 ? 772  ILE B CG1 1 
ATOM   5408  C CG2 . ILE A 1 740 ? 176.127 204.010 231.029 1.00 126.95 ? 772  ILE B CG2 1 
ATOM   5409  C CD1 . ILE A 1 740 ? 176.999 205.192 228.178 1.00 126.95 ? 772  ILE B CD1 1 
ATOM   5410  N N   . LYS A 1 741 ? 178.889 204.048 233.370 1.00 86.41  ? 773  LYS B N   1 
ATOM   5411  C CA  . LYS A 1 741 ? 179.092 203.161 234.517 1.00 86.41  ? 773  LYS B CA  1 
ATOM   5412  C C   . LYS A 1 741 ? 179.062 203.958 235.819 1.00 86.41  ? 773  LYS B C   1 
ATOM   5413  O O   . LYS A 1 741 ? 178.525 203.513 236.834 1.00 86.41  ? 773  LYS B O   1 
ATOM   5414  C CB  . LYS A 1 741 ? 180.420 202.404 234.421 1.00 123.60 ? 773  LYS B CB  1 
ATOM   5415  C CG  . LYS A 1 741 ? 180.518 201.309 233.380 1.00 123.60 ? 773  LYS B CG  1 
ATOM   5416  C CD  . LYS A 1 741 ? 181.907 200.640 233.451 1.00 123.60 ? 773  LYS B CD  1 
ATOM   5417  C CE  . LYS A 1 741 ? 182.040 199.475 232.475 1.00 123.60 ? 773  LYS B CE  1 
ATOM   5418  N NZ  . LYS A 1 741 ? 183.384 198.818 232.560 1.00 123.60 ? 773  LYS B NZ  1 
ATOM   5419  N N   . THR A 1 742 ? 179.558 205.176 235.755 1.00 83.10  ? 774  THR B N   1 
ATOM   5420  C CA  . THR A 1 742 ? 179.635 206.091 236.866 1.00 83.10  ? 774  THR B CA  1 
ATOM   5421  C C   . THR A 1 742 ? 178.377 206.917 237.143 1.00 83.10  ? 774  THR B C   1 
ATOM   5422  O O   . THR A 1 742 ? 178.394 207.789 238.010 1.00 83.10  ? 774  THR B O   1 
ATOM   5423  C CB  . THR A 1 742 ? 180.814 207.056 236.694 1.00 113.76 ? 774  THR B CB  1 
ATOM   5424  O OG1 . THR A 1 742 ? 180.739 207.666 235.402 1.00 113.76 ? 774  THR B OG1 1 
ATOM   5425  C CG2 . THR A 1 742 ? 182.150 206.357 236.856 1.00 113.76 ? 774  THR B CG2 1 
ATOM   5426  N N   . ARG A 1 743 ? 177.257 206.662 236.470 1.00 79.97  ? 775  ARG B N   1 
ATOM   5427  C CA  . ARG A 1 743 ? 176.065 207.469 236.753 1.00 79.97  ? 775  ARG B CA  1 
ATOM   5428  C C   . ARG A 1 743 ? 175.599 207.397 238.214 1.00 79.97  ? 775  ARG B C   1 
ATOM   5429  O O   . ARG A 1 743 ? 175.016 208.355 238.722 1.00 79.97  ? 775  ARG B O   1 
ATOM   5430  C CB  . ARG A 1 743 ? 174.894 207.058 235.879 1.00 112.31 ? 775  ARG B CB  1 
ATOM   5431  C CG  . ARG A 1 743 ? 174.997 207.453 234.434 1.00 112.31 ? 775  ARG B CG  1 
ATOM   5432  C CD  . ARG A 1 743 ? 173.865 206.910 233.640 1.00 112.31 ? 775  ARG B CD  1 
ATOM   5433  N NE  . ARG A 1 743 ? 173.927 205.455 233.545 1.00 112.31 ? 775  ARG B NE  1 
ATOM   5434  C CZ  . ARG A 1 743 ? 172.935 204.658 233.077 1.00 112.31 ? 775  ARG B CZ  1 
ATOM   5435  N NH1 . ARG A 1 743 ? 173.117 203.348 233.038 1.00 112.31 ? 775  ARG B NH1 1 
ATOM   5436  N NH2 . ARG A 1 743 ? 171.793 205.176 232.658 1.00 112.31 ? 775  ARG B NH2 1 
ATOM   5437  N N   . GLY A 1 744 ? 175.878 206.294 238.913 1.00 73.59  ? 776  GLY B N   1 
ATOM   5438  C CA  . GLY A 1 744 ? 175.462 206.152 240.306 1.00 73.59  ? 776  GLY B CA  1 
ATOM   5439  C C   . GLY A 1 744 ? 176.458 206.756 241.305 1.00 73.59  ? 776  GLY B C   1 
ATOM   5440  O O   . GLY A 1 744 ? 176.232 206.697 242.517 1.00 73.59  ? 776  GLY B O   1 
ATOM   5441  N N   . VAL A 1 745 ? 177.553 207.321 240.806 1.00 71.29  ? 777  VAL B N   1 
ATOM   5442  C CA  . VAL A 1 745 ? 178.590 207.881 241.649 1.00 71.29  ? 777  VAL B CA  1 
ATOM   5443  C C   . VAL A 1 745 ? 178.138 209.198 242.291 1.00 71.29  ? 777  VAL B C   1 
ATOM   5444  O O   . VAL A 1 745 ? 177.668 210.092 241.585 1.00 71.29  ? 777  VAL B O   1 
ATOM   5445  C CB  . VAL A 1 745 ? 179.858 208.115 240.818 1.00 100.39 ? 777  VAL B CB  1 
ATOM   5446  C CG1 . VAL A 1 745 ? 180.899 208.799 241.605 1.00 100.39 ? 777  VAL B CG1 1 
ATOM   5447  C CG2 . VAL A 1 745 ? 180.401 206.795 240.394 1.00 100.39 ? 777  VAL B CG2 1 
ATOM   5448  N N   . PRO A 1 746 ? 178.241 209.343 243.623 1.00 66.53  ? 778  PRO B N   1 
ATOM   5449  C CA  . PRO A 1 746 ? 177.871 210.510 244.400 1.00 66.53  ? 778  PRO B CA  1 
ATOM   5450  C C   . PRO A 1 746 ? 178.835 211.676 244.238 1.00 66.53  ? 778  PRO B C   1 
ATOM   5451  O O   . PRO A 1 746 ? 179.994 211.507 243.855 1.00 66.53  ? 778  PRO B O   1 
ATOM   5452  C CB  . PRO A 1 746 ? 177.859 209.969 245.833 1.00 113.69 ? 778  PRO B CB  1 
ATOM   5453  C CG  . PRO A 1 746 ? 178.846 208.854 245.829 1.00 113.69 ? 778  PRO B CG  1 
ATOM   5454  C CD  . PRO A 1 746 ? 178.711 208.222 244.462 1.00 113.69 ? 778  PRO B CD  1 
ATOM   5455  N N   . GLU A 1 747 ? 178.363 212.831 244.669 1.00 59.44  ? 779  GLU B N   1 
ATOM   5456  C CA  . GLU A 1 747 ? 179.043 214.125 244.669 1.00 59.44  ? 779  GLU B CA  1 
ATOM   5457  C C   . GLU A 1 747 ? 180.282 214.191 245.565 1.00 59.44  ? 779  GLU B C   1 
ATOM   5458  O O   . GLU A 1 747 ? 181.024 215.174 245.544 1.00 59.44  ? 779  GLU B O   1 
ATOM   5459  C CB  . GLU A 1 747 ? 178.035 215.201 245.063 1.00 78.34  ? 779  GLU B CB  1 
ATOM   5460  C CG  . GLU A 1 747 ? 176.892 215.380 244.045 1.00 78.34  ? 779  GLU B CG  1 
ATOM   5461  C CD  . GLU A 1 747 ? 175.803 214.321 244.155 1.00 78.34  ? 779  GLU B CD  1 
ATOM   5462  O OE1 . GLU A 1 747 ? 175.848 213.543 245.090 1.00 78.34  ? 779  GLU B OE1 1 
ATOM   5463  O OE2 . GLU A 1 747 ? 174.961 214.265 243.294 1.00 78.34  ? 779  GLU B OE2 1 
ATOM   5464  N N   . THR A 1 748 ? 180.486 213.160 246.384 1.00 56.44  ? 780  THR B N   1 
ATOM   5465  C CA  . THR A 1 748 ? 181.630 213.083 247.276 1.00 56.44  ? 780  THR B CA  1 
ATOM   5466  C C   . THR A 1 748 ? 182.899 212.824 246.463 1.00 56.44  ? 780  THR B C   1 
ATOM   5467  O O   . THR A 1 748 ? 184.013 213.014 246.956 1.00 56.44  ? 780  THR B O   1 
ATOM   5468  C CB  . THR A 1 748 ? 181.445 211.966 248.311 1.00 77.26  ? 780  THR B CB  1 
ATOM   5469  O OG1 . THR A 1 748 ? 181.391 210.701 247.646 1.00 77.26  ? 780  THR B OG1 1 
ATOM   5470  C CG2 . THR A 1 748 ? 180.131 212.187 249.043 1.00 77.26  ? 780  THR B CG2 1 
ATOM   5471  N N   . PHE A 1 749 ? 182.732 212.401 245.210 1.00 56.54  ? 781  PHE B N   1 
ATOM   5472  C CA  . PHE A 1 749 ? 183.852 212.238 244.311 1.00 56.54  ? 781  PHE B CA  1 
ATOM   5473  C C   . PHE A 1 749 ? 183.940 213.582 243.613 1.00 56.54  ? 781  PHE B C   1 
ATOM   5474  O O   . PHE A 1 749 ? 183.092 213.920 242.781 1.00 56.54  ? 781  PHE B O   1 
ATOM   5475  C CB  . PHE A 1 749 ? 183.612 211.104 243.338 1.00 76.46  ? 781  PHE B CB  1 
ATOM   5476  C CG  . PHE A 1 749 ? 183.660 209.739 243.923 1.00 76.46  ? 781  PHE B CG  1 
ATOM   5477  C CD1 . PHE A 1 749 ? 182.544 209.169 244.497 1.00 76.46  ? 781  PHE B CD1 1 
ATOM   5478  C CD2 . PHE A 1 749 ? 184.826 208.998 243.860 1.00 76.46  ? 781  PHE B CD2 1 
ATOM   5479  C CE1 . PHE A 1 749 ? 182.589 207.880 244.994 1.00 76.46  ? 781  PHE B CE1 1 
ATOM   5480  C CE2 . PHE A 1 749 ? 184.875 207.722 244.347 1.00 76.46  ? 781  PHE B CE2 1 
ATOM   5481  C CZ  . PHE A 1 749 ? 183.755 207.156 244.912 1.00 76.46  ? 781  PHE B CZ  1 
ATOM   5482  N N   . ASN A 1 750 ? 185.000 214.319 243.909 1.00 61.64  ? 782  ASN B N   1 
ATOM   5483  C CA  . ASN A 1 750 ? 185.123 215.712 243.500 1.00 61.64  ? 782  ASN B CA  1 
ATOM   5484  C C   . ASN A 1 750 ? 184.971 215.985 242.008 1.00 61.64  ? 782  ASN B C   1 
ATOM   5485  O O   . ASN A 1 750 ? 184.379 216.997 241.626 1.00 61.64  ? 782  ASN B O   1 
ATOM   5486  C CB  . ASN A 1 750 ? 186.489 216.225 243.913 1.00 81.99  ? 782  ASN B CB  1 
ATOM   5487  C CG  . ASN A 1 750 ? 186.690 216.381 245.385 1.00 81.99  ? 782  ASN B CG  1 
ATOM   5488  O OD1 . ASN A 1 750 ? 185.764 216.330 246.196 1.00 81.99  ? 782  ASN B OD1 1 
ATOM   5489  N ND2 . ASN A 1 750 ? 187.927 216.594 245.749 1.00 81.99  ? 782  ASN B ND2 1 
ATOM   5490  N N   . GLU A 1 751 ? 185.481 215.102 241.161 1.00 74.21  ? 783  GLU B N   1 
ATOM   5491  C CA  . GLU A 1 751 ? 185.398 215.330 239.723 1.00 74.21  ? 783  GLU B CA  1 
ATOM   5492  C C   . GLU A 1 751 ? 184.406 214.420 239.001 1.00 74.21  ? 783  GLU B C   1 
ATOM   5493  O O   . GLU A 1 751 ? 184.317 214.454 237.772 1.00 74.21  ? 783  GLU B O   1 
ATOM   5494  C CB  . GLU A 1 751 ? 186.776 215.164 239.097 1.00 97.80  ? 783  GLU B CB  1 
ATOM   5495  C CG  . GLU A 1 751 ? 187.823 216.203 239.556 1.00 97.80  ? 783  GLU B CG  1 
ATOM   5496  C CD  . GLU A 1 751 ? 188.463 215.898 240.910 1.00 97.80  ? 783  GLU B CD  1 
ATOM   5497  O OE1 . GLU A 1 751 ? 188.787 214.749 241.153 1.00 97.80  ? 783  GLU B OE1 1 
ATOM   5498  O OE2 . GLU A 1 751 ? 188.664 216.810 241.672 1.00 97.80  ? 783  GLU B OE2 1 
ATOM   5499  N N   . ALA A 1 752 ? 183.651 213.607 239.737 1.00 81.49  ? 784  ALA B N   1 
ATOM   5500  C CA  . ALA A 1 752 ? 182.791 212.627 239.074 1.00 81.49  ? 784  ALA B CA  1 
ATOM   5501  C C   . ALA A 1 752 ? 181.731 213.243 238.192 1.00 81.49  ? 784  ALA B C   1 
ATOM   5502  O O   . ALA A 1 752 ? 181.392 212.691 237.145 1.00 81.49  ? 784  ALA B O   1 
ATOM   5503  C CB  . ALA A 1 752 ? 182.111 211.745 240.094 1.00 110.09 ? 784  ALA B CB  1 
ATOM   5504  N N   . LYS A 1 753 ? 181.202 214.376 238.590 1.00 85.05  ? 785  LYS B N   1 
ATOM   5505  C CA  . LYS A 1 753 ? 180.146 214.956 237.817 1.00 85.05  ? 785  LYS B CA  1 
ATOM   5506  C C   . LYS A 1 753 ? 180.685 215.676 236.582 1.00 85.05  ? 785  LYS B C   1 
ATOM   5507  O O   . LYS A 1 753 ? 180.351 215.239 235.474 1.00 85.05  ? 785  LYS B O   1 
ATOM   5508  C CB  . LYS A 1 753 ? 179.272 215.836 238.712 1.00 121.66 ? 785  LYS B CB  1 
ATOM   5509  C CG  . LYS A 1 753 ? 178.600 215.054 239.873 1.00 121.66 ? 785  LYS B CG  1 
ATOM   5510  C CD  . LYS A 1 753 ? 177.617 213.971 239.404 1.00 121.66 ? 785  LYS B CD  1 
ATOM   5511  C CE  . LYS A 1 753 ? 176.959 213.275 240.603 1.00 121.66 ? 785  LYS B CE  1 
ATOM   5512  N NZ  . LYS A 1 753 ? 176.016 212.185 240.185 1.00 121.66 ? 785  LYS B NZ  1 
ATOM   5513  N N   . PRO A 1 754 ? 181.604 216.673 236.671 1.00 88.69  ? 786  PRO B N   1 
ATOM   5514  C CA  . PRO A 1 754 ? 182.062 217.409 235.516 1.00 88.69  ? 786  PRO B CA  1 
ATOM   5515  C C   . PRO A 1 754 ? 182.702 216.506 234.479 1.00 88.69  ? 786  PRO B C   1 
ATOM   5516  O O   . PRO A 1 754 ? 182.657 216.840 233.303 1.00 88.69  ? 786  PRO B O   1 
ATOM   5517  C CB  . PRO A 1 754 ? 183.047 218.415 236.112 1.00 151.55 ? 786  PRO B CB  1 
ATOM   5518  C CG  . PRO A 1 754 ? 183.448 217.846 237.430 1.00 151.55 ? 786  PRO B CG  1 
ATOM   5519  C CD  . PRO A 1 754 ? 182.213 217.152 237.937 1.00 151.55 ? 786  PRO B CD  1 
ATOM   5520  N N   . ILE A 1 755 ? 183.237 215.341 234.865 1.00 89.54  ? 787  ILE B N   1 
ATOM   5521  C CA  . ILE A 1 755 ? 183.778 214.463 233.845 1.00 89.54  ? 787  ILE B CA  1 
ATOM   5522  C C   . ILE A 1 755 ? 182.650 213.963 232.957 1.00 89.54  ? 787  ILE B C   1 
ATOM   5523  O O   . ILE A 1 755 ? 182.831 213.799 231.744 1.00 89.54  ? 787  ILE B O   1 
ATOM   5524  C CB  . ILE A 1 755 ? 184.558 213.264 234.418 1.00 127.27 ? 787  ILE B CB  1 
ATOM   5525  C CG1 . ILE A 1 755 ? 185.858 213.756 235.093 1.00 127.27 ? 787  ILE B CG1 1 
ATOM   5526  C CG2 . ILE A 1 755 ? 184.878 212.267 233.276 1.00 127.27 ? 787  ILE B CG2 1 
ATOM   5527  C CD1 . ILE A 1 755 ? 186.577 212.713 235.939 1.00 127.27 ? 787  ILE B CD1 1 
ATOM   5528  N N   . GLY A 1 756 ? 181.510 213.616 233.562 1.00 89.61  ? 788  GLY B N   1 
ATOM   5529  C CA  . GLY A 1 756 ? 180.402 213.097 232.789 1.00 89.61  ? 788  GLY B CA  1 
ATOM   5530  C C   . GLY A 1 756 ? 179.971 214.157 231.811 1.00 89.61  ? 788  GLY B C   1 
ATOM   5531  O O   . GLY A 1 756 ? 179.734 213.866 230.635 1.00 89.61  ? 788  GLY B O   1 
ATOM   5532  N N   . PHE A 1 757 ? 179.995 215.400 232.274 1.00 91.26  ? 789  PHE B N   1 
ATOM   5533  C CA  . PHE A 1 757 ? 179.594 216.503 231.436 1.00 91.26  ? 789  PHE B CA  1 
ATOM   5534  C C   . PHE A 1 757 ? 180.567 216.738 230.317 1.00 91.26  ? 789  PHE B C   1 
ATOM   5535  O O   . PHE A 1 757 ? 180.144 217.038 229.188 1.00 91.26  ? 789  PHE B O   1 
ATOM   5536  C CB  . PHE A 1 757 ? 179.395 217.743 232.255 1.00 123.41 ? 789  PHE B CB  1 
ATOM   5537  C CG  . PHE A 1 757 ? 178.150 217.638 233.012 1.00 123.41 ? 789  PHE B CG  1 
ATOM   5538  C CD1 . PHE A 1 757 ? 176.938 217.909 232.408 1.00 123.41 ? 789  PHE B CD1 1 
ATOM   5539  C CD2 . PHE A 1 757 ? 178.164 217.239 234.318 1.00 123.41 ? 789  PHE B CD2 1 
ATOM   5540  C CE1 . PHE A 1 757 ? 175.762 217.775 233.104 1.00 123.41 ? 789  PHE B CE1 1 
ATOM   5541  C CE2 . PHE A 1 757 ? 177.007 217.096 235.023 1.00 123.41 ? 789  PHE B CE2 1 
ATOM   5542  C CZ  . PHE A 1 757 ? 175.795 217.364 234.417 1.00 123.41 ? 789  PHE B CZ  1 
ATOM   5543  N N   . THR A 1 758 ? 181.866 216.572 230.578 1.00 93.14  ? 790  THR B N   1 
ATOM   5544  C CA  . THR A 1 758 ? 182.765 216.774 229.481 1.00 93.14  ? 790  THR B CA  1 
ATOM   5545  C C   . THR A 1 758 ? 182.496 215.743 228.439 1.00 93.14  ? 790  THR B C   1 
ATOM   5546  O O   . THR A 1 758 ? 182.447 216.091 227.264 1.00 93.14  ? 790  THR B O   1 
ATOM   5547  C CB  . THR A 1 758 ? 184.264 216.659 229.849 1.00 127.50 ? 790  THR B CB  1 
ATOM   5548  O OG1 . THR A 1 758 ? 184.532 215.402 230.460 1.00 127.50 ? 790  THR B OG1 1 
ATOM   5549  C CG2 . THR A 1 758 ? 184.671 217.712 230.733 1.00 127.50 ? 790  THR B CG2 1 
ATOM   5550  N N   . MET A 1 759 ? 182.210 214.504 228.834 1.00 92.93  ? 791  MET B N   1 
ATOM   5551  C CA  . MET A 1 759 ? 181.944 213.517 227.809 1.00 92.93  ? 791  MET B CA  1 
ATOM   5552  C C   . MET A 1 759 ? 180.621 213.708 227.098 1.00 92.93  ? 791  MET B C   1 
ATOM   5553  O O   . MET A 1 759 ? 180.531 213.497 225.882 1.00 92.93  ? 791  MET B O   1 
ATOM   5554  C CB  . MET A 1 759 ? 182.029 212.110 228.364 1.00 129.29 ? 791  MET B CB  1 
ATOM   5555  C CG  . MET A 1 759 ? 183.433 211.688 228.753 1.00 129.29 ? 791  MET B CG  1 
ATOM   5556  S SD  . MET A 1 759 ? 184.663 212.003 227.424 1.00 129.29 ? 791  MET B SD  1 
ATOM   5557  C CE  . MET A 1 759 ? 184.018 211.091 226.034 1.00 129.29 ? 791  MET B CE  1 
ATOM   5558  N N   . TYR A 1 760 ? 179.621 214.233 227.800 1.00 93.34  ? 792  TYR B N   1 
ATOM   5559  C CA  . TYR A 1 760 ? 178.327 214.420 227.177 1.00 93.34  ? 792  TYR B CA  1 
ATOM   5560  C C   . TYR A 1 760 ? 178.494 215.325 225.976 1.00 93.34  ? 792  TYR B C   1 
ATOM   5561  O O   . TYR A 1 760 ? 177.887 215.091 224.931 1.00 93.34  ? 792  TYR B O   1 
ATOM   5562  C CB  . TYR A 1 760 ? 177.322 215.080 228.134 1.00 125.29 ? 792  TYR B CB  1 
ATOM   5563  C CG  . TYR A 1 760 ? 176.895 214.280 229.368 1.00 125.29 ? 792  TYR B CG  1 
ATOM   5564  C CD1 . TYR A 1 760 ? 177.022 212.901 229.444 1.00 125.29 ? 792  TYR B CD1 1 
ATOM   5565  C CD2 . TYR A 1 760 ? 176.366 214.971 230.449 1.00 125.29 ? 792  TYR B CD2 1 
ATOM   5566  C CE1 . TYR A 1 760 ? 176.635 212.244 230.593 1.00 125.29 ? 792  TYR B CE1 1 
ATOM   5567  C CE2 . TYR A 1 760 ? 175.988 214.316 231.589 1.00 125.29 ? 792  TYR B CE2 1 
ATOM   5568  C CZ  . TYR A 1 760 ? 176.120 212.961 231.667 1.00 125.29 ? 792  TYR B CZ  1 
ATOM   5569  O OH  . TYR A 1 760 ? 175.742 212.297 232.811 1.00 125.29 ? 792  TYR B OH  1 
ATOM   5570  N N   . THR A 1 761 ? 179.319 216.361 226.120 1.00 93.37  ? 793  THR B N   1 
ATOM   5571  C CA  . THR A 1 761 ? 179.552 217.263 225.005 1.00 93.37  ? 793  THR B CA  1 
ATOM   5572  C C   . THR A 1 761 ? 180.665 216.770 224.069 1.00 93.37  ? 793  THR B C   1 
ATOM   5573  O O   . THR A 1 761 ? 180.487 216.738 222.847 1.00 93.37  ? 793  THR B O   1 
ATOM   5574  C CB  . THR A 1 761 ? 179.880 218.684 225.505 1.00 127.81 ? 793  THR B CB  1 
ATOM   5575  O OG1 . THR A 1 761 ? 178.781 219.192 226.274 1.00 127.81 ? 793  THR B OG1 1 
ATOM   5576  C CG2 . THR A 1 761 ? 180.116 219.607 224.324 1.00 127.81 ? 793  THR B CG2 1 
ATOM   5577  N N   . THR A 1 762 ? 181.779 216.327 224.630 1.00 92.74  ? 794  THR B N   1 
ATOM   5578  C CA  . THR A 1 762 ? 182.972 215.955 223.880 1.00 92.74  ? 794  THR B CA  1 
ATOM   5579  C C   . THR A 1 762 ? 182.703 214.905 222.841 1.00 92.74  ? 794  THR B C   1 
ATOM   5580  O O   . THR A 1 762 ? 183.218 214.991 221.722 1.00 92.74  ? 794  THR B O   1 
ATOM   5581  C CB  . THR A 1 762 ? 184.082 215.425 224.808 1.00 126.95 ? 794  THR B CB  1 
ATOM   5582  O OG1 . THR A 1 762 ? 184.477 216.433 225.721 1.00 126.95 ? 794  THR B OG1 1 
ATOM   5583  C CG2 . THR A 1 762 ? 185.258 215.023 224.026 1.00 126.95 ? 794  THR B CG2 1 
ATOM   5584  N N   . CYS A 1 763 ? 181.914 213.901 223.181 1.00 93.42  ? 795  CYS B N   1 
ATOM   5585  C CA  . CYS A 1 763 ? 181.667 212.850 222.227 1.00 93.42  ? 795  CYS B CA  1 
ATOM   5586  C C   . CYS A 1 763 ? 180.909 213.347 221.003 1.00 93.42  ? 795  CYS B C   1 
ATOM   5587  O O   . CYS A 1 763 ? 181.011 212.753 219.939 1.00 93.42  ? 795  CYS B O   1 
ATOM   5588  C CB  . CYS A 1 763 ? 180.892 211.714 222.884 1.00 124.43 ? 795  CYS B CB  1 
ATOM   5589  S SG  . CYS A 1 763 ? 179.231 212.172 223.418 1.00 124.43 ? 795  CYS B SG  1 
ATOM   5590  N N   . ILE A 1 764 ? 180.187 214.453 221.119 1.00 93.44  ? 796  ILE B N   1 
ATOM   5591  C CA  . ILE A 1 764 ? 179.412 214.961 220.013 1.00 93.44  ? 796  ILE B CA  1 
ATOM   5592  C C   . ILE A 1 764 ? 180.318 215.814 219.186 1.00 93.44  ? 796  ILE B C   1 
ATOM   5593  O O   . ILE A 1 764 ? 180.295 215.773 217.953 1.00 93.44  ? 796  ILE B O   1 
ATOM   5594  C CB  . ILE A 1 764 ? 178.207 215.771 220.487 1.00 132.81 ? 796  ILE B CB  1 
ATOM   5595  C CG1 . ILE A 1 764 ? 177.313 214.884 221.416 1.00 132.81 ? 796  ILE B CG1 1 
ATOM   5596  C CG2 . ILE A 1 764 ? 177.434 216.319 219.278 1.00 132.81 ? 796  ILE B CG2 1 
ATOM   5597  C CD1 . ILE A 1 764 ? 176.828 213.548 220.831 1.00 132.81 ? 796  ILE B CD1 1 
ATOM   5598  N N   . VAL A 1 765 ? 181.148 216.586 219.870 1.00 92.96  ? 797  VAL B N   1 
ATOM   5599  C CA  . VAL A 1 765 ? 182.075 217.440 219.172 1.00 92.96  ? 797  VAL B CA  1 
ATOM   5600  C C   . VAL A 1 765 ? 182.900 216.566 218.272 1.00 92.96  ? 797  VAL B C   1 
ATOM   5601  O O   . VAL A 1 765 ? 183.122 216.879 217.092 1.00 92.96  ? 797  VAL B O   1 
ATOM   5602  C CB  . VAL A 1 765 ? 183.009 218.137 220.184 1.00 130.91 ? 797  VAL B CB  1 
ATOM   5603  C CG1 . VAL A 1 765 ? 184.131 218.812 219.492 1.00 130.91 ? 797  VAL B CG1 1 
ATOM   5604  C CG2 . VAL A 1 765 ? 182.229 219.163 220.989 1.00 130.91 ? 797  VAL B CG2 1 
ATOM   5605  N N   . TRP A 1 766 ? 183.360 215.458 218.820 1.00 91.11  ? 798  TRP B N   1 
ATOM   5606  C CA  . TRP A 1 766 ? 184.107 214.597 217.989 1.00 91.11  ? 798  TRP B CA  1 
ATOM   5607  C C   . TRP A 1 766 ? 183.316 213.910 216.923 1.00 91.11  ? 798  TRP B C   1 
ATOM   5608  O O   . TRP A 1 766 ? 183.664 213.983 215.759 1.00 91.11  ? 798  TRP B O   1 
ATOM   5609  C CB  . TRP A 1 766 ? 184.805 213.499 218.715 1.00 121.98 ? 798  TRP B CB  1 
ATOM   5610  C CG  . TRP A 1 766 ? 185.457 212.757 217.677 1.00 121.98 ? 798  TRP B CG  1 
ATOM   5611  C CD1 . TRP A 1 766 ? 185.148 211.537 217.174 1.00 121.98 ? 798  TRP B CD1 1 
ATOM   5612  C CD2 . TRP A 1 766 ? 186.528 213.259 216.886 1.00 121.98 ? 798  TRP B CD2 1 
ATOM   5613  N NE1 . TRP A 1 766 ? 185.955 211.260 216.122 1.00 121.98 ? 798  TRP B NE1 1 
ATOM   5614  C CE2 . TRP A 1 766 ? 186.800 212.312 215.931 1.00 121.98 ? 798  TRP B CE2 1 
ATOM   5615  C CE3 . TRP A 1 766 ? 187.264 214.449 216.902 1.00 121.98 ? 798  TRP B CE3 1 
ATOM   5616  C CZ2 . TRP A 1 766 ? 187.763 212.506 214.996 1.00 121.98 ? 798  TRP B CZ2 1 
ATOM   5617  C CZ3 . TRP A 1 766 ? 188.217 214.636 215.971 1.00 121.98 ? 798  TRP B CZ3 1 
ATOM   5618  C CH2 . TRP A 1 766 ? 188.461 213.705 215.049 1.00 121.98 ? 798  TRP B CH2 1 
ATOM   5619  N N   . LEU A 1 767 ? 182.230 213.248 217.272 1.00 91.01  ? 799  LEU B N   1 
ATOM   5620  C CA  . LEU A 1 767 ? 181.560 212.439 216.280 1.00 91.01  ? 799  LEU B CA  1 
ATOM   5621  C C   . LEU A 1 767 ? 181.043 213.239 215.114 1.00 91.01  ? 799  LEU B C   1 
ATOM   5622  O O   . LEU A 1 767 ? 181.021 212.740 213.988 1.00 91.01  ? 799  LEU B O   1 
ATOM   5623  C CB  . LEU A 1 767 ? 180.459 211.641 216.954 1.00 129.36 ? 799  LEU B CB  1 
ATOM   5624  C CG  . LEU A 1 767 ? 180.968 210.525 217.914 1.00 129.36 ? 799  LEU B CG  1 
ATOM   5625  C CD1 . LEU A 1 767 ? 179.792 209.984 218.704 1.00 129.36 ? 799  LEU B CD1 1 
ATOM   5626  C CD2 . LEU A 1 767 ? 181.648 209.376 217.125 1.00 129.36 ? 799  LEU B CD2 1 
ATOM   5627  N N   . ALA A 1 768 ? 180.733 214.514 215.333 1.00 91.05  ? 800  ALA B N   1 
ATOM   5628  C CA  . ALA A 1 768 ? 180.282 215.408 214.279 1.00 91.05  ? 800  ALA B CA  1 
ATOM   5629  C C   . ALA A 1 768 ? 181.325 215.494 213.155 1.00 91.05  ? 800  ALA B C   1 
ATOM   5630  O O   . ALA A 1 768 ? 180.998 215.836 212.009 1.00 91.05  ? 800  ALA B O   1 
ATOM   5631  C CB  . ALA A 1 768 ? 180.031 216.783 214.853 1.00 123.00 ? 800  ALA B CB  1 
ATOM   5632  N N   . PHE A 1 769 ? 182.581 215.217 213.492 1.00 90.24  ? 801  PHE B N   1 
ATOM   5633  C CA  . PHE A 1 769 ? 183.688 215.250 212.577 1.00 90.24  ? 801  PHE B CA  1 
ATOM   5634  C C   . PHE A 1 769 ? 183.480 214.344 211.397 1.00 90.24  ? 801  PHE B C   1 
ATOM   5635  O O   . PHE A 1 769 ? 183.804 214.697 210.266 1.00 90.24  ? 801  PHE B O   1 
ATOM   5636  C CB  . PHE A 1 769 ? 184.984 214.817 213.258 1.00 122.04 ? 801  PHE B CB  1 
ATOM   5637  C CG  . PHE A 1 769 ? 186.052 214.690 212.296 1.00 122.04 ? 801  PHE B CG  1 
ATOM   5638  C CD1 . PHE A 1 769 ? 186.652 215.775 211.806 1.00 122.04 ? 801  PHE B CD1 1 
ATOM   5639  C CD2 . PHE A 1 769 ? 186.441 213.451 211.848 1.00 122.04 ? 801  PHE B CD2 1 
ATOM   5640  C CE1 . PHE A 1 769 ? 187.606 215.663 210.853 1.00 122.04 ? 801  PHE B CE1 1 
ATOM   5641  C CE2 . PHE A 1 769 ? 187.411 213.321 210.910 1.00 122.04 ? 801  PHE B CE2 1 
ATOM   5642  C CZ  . PHE A 1 769 ? 187.994 214.432 210.403 1.00 122.04 ? 801  PHE B CZ  1 
ATOM   5643  N N   . ILE A 1 770 ? 183.043 213.118 211.643 1.00 87.01  ? 802  ILE B N   1 
ATOM   5644  C CA  . ILE A 1 770 ? 182.991 212.186 210.546 1.00 87.01  ? 802  ILE B CA  1 
ATOM   5645  C C   . ILE A 1 770 ? 182.024 212.616 209.454 1.00 87.01  ? 802  ILE B C   1 
ATOM   5646  O O   . ILE A 1 770 ? 182.453 212.737 208.306 1.00 87.01  ? 802  ILE B O   1 
ATOM   5647  C CB  . ILE A 1 770 ? 182.754 210.738 211.065 1.00 123.67 ? 802  ILE B CB  1 
ATOM   5648  C CG1 . ILE A 1 770 ? 183.978 210.240 211.891 1.00 123.67 ? 802  ILE B CG1 1 
ATOM   5649  C CG2 . ILE A 1 770 ? 182.405 209.799 209.919 1.00 123.67 ? 802  ILE B CG2 1 
ATOM   5650  C CD1 . ILE A 1 770 ? 185.278 210.028 211.117 1.00 123.67 ? 802  ILE B CD1 1 
ATOM   5651  N N   . PRO A 1 771 ? 180.731 212.889 209.713 1.00 89.83  ? 803  PRO B N   1 
ATOM   5652  C CA  . PRO A 1 771 ? 179.813 213.333 208.693 1.00 89.83  ? 803  PRO B CA  1 
ATOM   5653  C C   . PRO A 1 771 ? 180.325 214.533 207.912 1.00 89.83  ? 803  PRO B C   1 
ATOM   5654  O O   . PRO A 1 771 ? 180.172 214.574 206.689 1.00 89.83  ? 803  PRO B O   1 
ATOM   5655  C CB  . PRO A 1 771 ? 178.590 213.738 209.527 1.00 153.50 ? 803  PRO B CB  1 
ATOM   5656  C CG  . PRO A 1 771 ? 178.642 212.832 210.712 1.00 153.50 ? 803  PRO B CG  1 
ATOM   5657  C CD  . PRO A 1 771 ? 180.101 212.709 211.035 1.00 153.50 ? 803  PRO B CD  1 
ATOM   5658  N N   . ILE A 1 772 ? 181.016 215.460 208.575 1.00 89.66  ? 804  ILE B N   1 
ATOM   5659  C CA  . ILE A 1 772 ? 181.500 216.616 207.857 1.00 89.66  ? 804  ILE B CA  1 
ATOM   5660  C C   . ILE A 1 772 ? 182.682 216.246 206.997 1.00 89.66  ? 804  ILE B C   1 
ATOM   5661  O O   . ILE A 1 772 ? 182.764 216.628 205.827 1.00 89.66  ? 804  ILE B O   1 
ATOM   5662  C CB  . ILE A 1 772 ? 181.886 217.738 208.805 1.00 127.44 ? 804  ILE B CB  1 
ATOM   5663  C CG1 . ILE A 1 772 ? 180.640 218.226 209.556 1.00 127.44 ? 804  ILE B CG1 1 
ATOM   5664  C CG2 . ILE A 1 772 ? 182.499 218.910 207.948 1.00 127.44 ? 804  ILE B CG2 1 
ATOM   5665  C CD1 . ILE A 1 772 ? 180.952 219.110 210.751 1.00 127.44 ? 804  ILE B CD1 1 
ATOM   5666  N N   . PHE A 1 773 ? 183.610 215.499 207.568 1.00 85.99  ? 805  PHE B N   1 
ATOM   5667  C CA  . PHE A 1 773 ? 184.789 215.117 206.848 1.00 85.99  ? 805  PHE B CA  1 
ATOM   5668  C C   . PHE A 1 773 ? 184.414 214.430 205.568 1.00 85.99  ? 805  PHE B C   1 
ATOM   5669  O O   . PHE A 1 773 ? 184.919 214.752 204.491 1.00 85.99  ? 805  PHE B O   1 
ATOM   5670  C CB  . PHE A 1 773 ? 185.614 214.159 207.670 1.00 116.29 ? 805  PHE B CB  1 
ATOM   5671  C CG  . PHE A 1 773 ? 186.767 213.665 206.936 1.00 116.29 ? 805  PHE B CG  1 
ATOM   5672  C CD1 . PHE A 1 773 ? 187.917 214.401 206.848 1.00 116.29 ? 805  PHE B CD1 1 
ATOM   5673  C CD2 . PHE A 1 773 ? 186.703 212.459 206.294 1.00 116.29 ? 805  PHE B CD2 1 
ATOM   5674  C CE1 . PHE A 1 773 ? 188.988 213.923 206.136 1.00 116.29 ? 805  PHE B CE1 1 
ATOM   5675  C CE2 . PHE A 1 773 ? 187.750 211.974 205.583 1.00 116.29 ? 805  PHE B CE2 1 
ATOM   5676  C CZ  . PHE A 1 773 ? 188.901 212.701 205.502 1.00 116.29 ? 805  PHE B CZ  1 
ATOM   5677  N N   . PHE A 1 774 ? 183.521 213.466 205.656 1.00 85.72  ? 806  PHE B N   1 
ATOM   5678  C CA  . PHE A 1 774 ? 183.172 212.780 204.444 1.00 85.72  ? 806  PHE B CA  1 
ATOM   5679  C C   . PHE A 1 774 ? 182.292 213.617 203.533 1.00 85.72  ? 806  PHE B C   1 
ATOM   5680  O O   . PHE A 1 774 ? 182.539 213.685 202.327 1.00 85.72  ? 806  PHE B O   1 
ATOM   5681  C CB  . PHE A 1 774 ? 182.532 211.452 204.771 1.00 115.92 ? 806  PHE B CB  1 
ATOM   5682  C CG  . PHE A 1 774 ? 183.557 210.477 205.180 1.00 115.92 ? 806  PHE B CG  1 
ATOM   5683  C CD1 . PHE A 1 774 ? 184.322 209.844 204.221 1.00 115.92 ? 806  PHE B CD1 1 
ATOM   5684  C CD2 . PHE A 1 774 ? 183.791 210.203 206.502 1.00 115.92 ? 806  PHE B CD2 1 
ATOM   5685  C CE1 . PHE A 1 774 ? 185.294 208.953 204.577 1.00 115.92 ? 806  PHE B CE1 1 
ATOM   5686  C CE2 . PHE A 1 774 ? 184.776 209.302 206.869 1.00 115.92 ? 806  PHE B CE2 1 
ATOM   5687  C CZ  . PHE A 1 774 ? 185.522 208.681 205.901 1.00 115.92 ? 806  PHE B CZ  1 
ATOM   5688  N N   . GLY A 1 775 ? 181.320 214.337 204.079 1.00 84.92  ? 807  GLY B N   1 
ATOM   5689  C CA  . GLY A 1 775 ? 180.408 215.117 203.258 1.00 84.92  ? 807  GLY B CA  1 
ATOM   5690  C C   . GLY A 1 775 ? 181.122 216.169 202.422 1.00 84.92  ? 807  GLY B C   1 
ATOM   5691  O O   . GLY A 1 775 ? 180.738 216.447 201.284 1.00 84.92  ? 807  GLY B O   1 
ATOM   5692  N N   . THR A 1 776 ? 182.207 216.702 202.951 1.00 84.18  ? 808  THR B N   1 
ATOM   5693  C CA  . THR A 1 776 ? 182.967 217.733 202.281 1.00 84.18  ? 808  THR B CA  1 
ATOM   5694  C C   . THR A 1 776 ? 184.115 217.190 201.432 1.00 84.18  ? 808  THR B C   1 
ATOM   5695  O O   . THR A 1 776 ? 184.840 217.963 200.801 1.00 84.18  ? 808  THR B O   1 
ATOM   5696  C CB  . THR A 1 776 ? 183.480 218.751 203.311 1.00 115.23 ? 808  THR B CB  1 
ATOM   5697  O OG1 . THR A 1 776 ? 184.340 218.118 204.266 1.00 115.23 ? 808  THR B OG1 1 
ATOM   5698  C CG2 . THR A 1 776 ? 182.302 219.381 204.045 1.00 115.23 ? 808  THR B CG2 1 
ATOM   5699  N N   . SER A 1 777 ? 184.243 215.863 201.348 1.00 75.12  ? 809  SER B N   1 
ATOM   5700  C CA  . SER A 1 777 ? 185.323 215.190 200.624 1.00 75.12  ? 809  SER B CA  1 
ATOM   5701  C C   . SER A 1 777 ? 185.273 215.370 199.118 1.00 75.12  ? 809  SER B C   1 
ATOM   5702  O O   . SER A 1 777 ? 186.219 215.003 198.419 1.00 75.12  ? 809  SER B O   1 
ATOM   5703  C CB  . SER A 1 777 ? 185.306 213.699 200.904 1.00 100.06 ? 809  SER B CB  1 
ATOM   5704  O OG  . SER A 1 777 ? 184.175 213.082 200.326 1.00 100.06 ? 809  SER B OG  1 
ATOM   5705  N N   . GLN A 1 778 ? 184.139 215.819 198.599 1.00 75.78  ? 810  GLN B N   1 
ATOM   5706  C CA  . GLN A 1 778 ? 183.988 216.016 197.172 1.00 75.78  ? 810  GLN B CA  1 
ATOM   5707  C C   . GLN A 1 778 ? 184.170 217.474 196.748 1.00 75.78  ? 810  GLN B C   1 
ATOM   5708  O O   . GLN A 1 778 ? 184.056 217.791 195.563 1.00 75.78  ? 810  GLN B O   1 
ATOM   5709  C CB  . GLN A 1 778 ? 182.614 215.513 196.731 1.00 103.00 ? 810  GLN B CB  1 
ATOM   5710  C CG  . GLN A 1 778 ? 182.385 214.047 197.059 1.00 103.00 ? 810  GLN B CG  1 
ATOM   5711  C CD  . GLN A 1 778 ? 183.397 213.145 196.415 1.00 103.00 ? 810  GLN B CD  1 
ATOM   5712  O OE1 . GLN A 1 778 ? 183.538 213.119 195.189 1.00 103.00 ? 810  GLN B OE1 1 
ATOM   5713  N NE2 . GLN A 1 778 ? 184.130 212.406 197.241 1.00 103.00 ? 810  GLN B NE2 1 
ATOM   5714  N N   . SER A 1 779 ? 184.403 218.376 197.704 1.00 76.90  ? 811  SER B N   1 
ATOM   5715  C CA  . SER A 1 779 ? 184.516 219.796 197.372 1.00 76.90  ? 811  SER B CA  1 
ATOM   5716  C C   . SER A 1 779 ? 185.878 220.223 196.847 1.00 76.90  ? 811  SER B C   1 
ATOM   5717  O O   . SER A 1 779 ? 186.915 219.823 197.359 1.00 76.90  ? 811  SER B O   1 
ATOM   5718  C CB  . SER A 1 779 ? 184.186 220.659 198.562 1.00 102.43 ? 811  SER B CB  1 
ATOM   5719  O OG  . SER A 1 779 ? 184.403 222.016 198.246 1.00 102.43 ? 811  SER B OG  1 
ATOM   5720  N N   . ALA A 1 780 ? 185.893 221.154 195.892 1.00 70.15  ? 812  ALA B N   1 
ATOM   5721  C CA  . ALA A 1 780 ? 187.150 221.722 195.377 1.00 70.15  ? 812  ALA B CA  1 
ATOM   5722  C C   . ALA A 1 780 ? 187.924 222.426 196.493 1.00 70.15  ? 812  ALA B C   1 
ATOM   5723  O O   . ALA A 1 780 ? 189.144 222.578 196.435 1.00 70.15  ? 812  ALA B O   1 
ATOM   5724  C CB  . ALA A 1 780 ? 186.882 222.705 194.251 1.00 94.77  ? 812  ALA B CB  1 
ATOM   5725  N N   . ASP A 1 781 ? 187.186 222.875 197.496 1.00 77.89  ? 813  ASP B N   1 
ATOM   5726  C CA  . ASP A 1 781 ? 187.703 223.580 198.648 1.00 77.89  ? 813  ASP B CA  1 
ATOM   5727  C C   . ASP A 1 781 ? 188.008 222.678 199.830 1.00 77.89  ? 813  ASP B C   1 
ATOM   5728  O O   . ASP A 1 781 ? 188.403 223.166 200.898 1.00 77.89  ? 813  ASP B O   1 
ATOM   5729  C CB  . ASP A 1 781 ? 186.724 224.632 199.098 1.00 99.18  ? 813  ASP B CB  1 
ATOM   5730  C CG  . ASP A 1 781 ? 186.629 225.869 198.224 1.00 99.18  ? 813  ASP B CG  1 
ATOM   5731  O OD1 . ASP A 1 781 ? 187.504 226.142 197.441 1.00 99.18  ? 813  ASP B OD1 1 
ATOM   5732  O OD2 . ASP A 1 781 ? 185.700 226.609 198.443 1.00 99.18  ? 813  ASP B OD2 1 
ATOM   5733  N N   . LYS A 1 782 ? 187.915 221.362 199.637 1.00 82.19  ? 814  LYS B N   1 
ATOM   5734  C CA  . LYS A 1 782 ? 188.098 220.419 200.724 1.00 82.19  ? 814  LYS B CA  1 
ATOM   5735  C C   . LYS A 1 782 ? 189.431 220.574 201.404 1.00 82.19  ? 814  LYS B C   1 
ATOM   5736  O O   . LYS A 1 782 ? 189.543 220.327 202.600 1.00 82.19  ? 814  LYS B O   1 
ATOM   5737  C CB  . LYS A 1 782 ? 187.904 218.995 200.246 1.00 117.57 ? 814  LYS B CB  1 
ATOM   5738  C CG  . LYS A 1 782 ? 188.929 218.466 199.291 1.00 117.57 ? 814  LYS B CG  1 
ATOM   5739  C CD  . LYS A 1 782 ? 188.496 217.098 198.852 1.00 117.57 ? 814  LYS B CD  1 
ATOM   5740  C CE  . LYS A 1 782 ? 189.345 216.517 197.737 1.00 117.57 ? 814  LYS B CE  1 
ATOM   5741  N NZ  . LYS A 1 782 ? 189.068 217.194 196.462 1.00 117.57 ? 814  LYS B NZ  1 
ATOM   5742  N N   . LEU A 1 783 ? 190.450 221.063 200.698 1.00 81.58  ? 815  LEU B N   1 
ATOM   5743  C CA  . LEU A 1 783 ? 191.751 221.243 201.308 1.00 81.58  ? 815  LEU B CA  1 
ATOM   5744  C C   . LEU A 1 783 ? 191.635 222.042 202.595 1.00 81.58  ? 815  LEU B C   1 
ATOM   5745  O O   . LEU A 1 783 ? 192.285 221.717 203.597 1.00 81.58  ? 815  LEU B O   1 
ATOM   5746  C CB  . LEU A 1 783 ? 192.672 222.017 200.355 1.00 115.95 ? 815  LEU B CB  1 
ATOM   5747  C CG  . LEU A 1 783 ? 194.126 222.317 200.843 1.00 115.95 ? 815  LEU B CG  1 
ATOM   5748  C CD1 . LEU A 1 783 ? 194.912 221.017 201.043 1.00 115.95 ? 815  LEU B CD1 1 
ATOM   5749  C CD2 . LEU A 1 783 ? 194.795 223.261 199.835 1.00 115.95 ? 815  LEU B CD2 1 
ATOM   5750  N N   . TYR A 1 784 ? 190.803 223.090 202.600 1.00 87.00  ? 816  TYR B N   1 
ATOM   5751  C CA  . TYR A 1 784 ? 190.716 223.860 203.817 1.00 87.00  ? 816  TYR B CA  1 
ATOM   5752  C C   . TYR A 1 784 ? 189.495 223.439 204.586 1.00 87.00  ? 816  TYR B C   1 
ATOM   5753  O O   . TYR A 1 784 ? 189.486 223.525 205.809 1.00 87.00  ? 816  TYR B O   1 
ATOM   5754  C CB  . TYR A 1 784 ? 190.673 225.390 203.579 1.00 116.78 ? 816  TYR B CB  1 
ATOM   5755  C CG  . TYR A 1 784 ? 189.421 225.977 202.888 1.00 116.78 ? 816  TYR B CG  1 
ATOM   5756  C CD1 . TYR A 1 784 ? 188.251 226.221 203.611 1.00 116.78 ? 816  TYR B CD1 1 
ATOM   5757  C CD2 . TYR A 1 784 ? 189.470 226.320 201.561 1.00 116.78 ? 816  TYR B CD2 1 
ATOM   5758  C CE1 . TYR A 1 784 ? 187.146 226.762 202.990 1.00 116.78 ? 816  TYR B CE1 1 
ATOM   5759  C CE2 . TYR A 1 784 ? 188.369 226.877 200.954 1.00 116.78 ? 816  TYR B CE2 1 
ATOM   5760  C CZ  . TYR A 1 784 ? 187.202 227.092 201.659 1.00 116.78 ? 816  TYR B CZ  1 
ATOM   5761  O OH  . TYR A 1 784 ? 186.065 227.609 201.031 1.00 116.78 ? 816  TYR B OH  1 
ATOM   5762  N N   . ILE A 1 785 ? 188.482 222.913 203.914 1.00 87.89  ? 817  ILE B N   1 
ATOM   5763  C CA  . ILE A 1 785 ? 187.274 222.602 204.649 1.00 87.89  ? 817  ILE B CA  1 
ATOM   5764  C C   . ILE A 1 785 ? 187.499 221.413 205.556 1.00 87.89  ? 817  ILE B C   1 
ATOM   5765  O O   . ILE A 1 785 ? 187.117 221.445 206.728 1.00 87.89  ? 817  ILE B O   1 
ATOM   5766  C CB  . ILE A 1 785 ? 186.094 222.319 203.720 1.00 124.92 ? 817  ILE B CB  1 
ATOM   5767  C CG1 . ILE A 1 785 ? 185.765 223.581 202.952 1.00 124.92 ? 817  ILE B CG1 1 
ATOM   5768  C CG2 . ILE A 1 785 ? 184.896 221.875 204.557 1.00 124.92 ? 817  ILE B CG2 1 
ATOM   5769  C CD1 . ILE A 1 785 ? 184.846 223.381 201.794 1.00 124.92 ? 817  ILE B CD1 1 
ATOM   5770  N N   . GLN A 1 786 ? 188.101 220.350 205.035 1.00 87.61  ? 818  GLN B N   1 
ATOM   5771  C CA  . GLN A 1 786 ? 188.329 219.192 205.863 1.00 87.61  ? 818  GLN B CA  1 
ATOM   5772  C C   . GLN A 1 786 ? 189.378 219.485 206.917 1.00 87.61  ? 818  GLN B C   1 
ATOM   5773  O O   . GLN A 1 786 ? 189.285 218.983 208.044 1.00 87.61  ? 818  GLN B O   1 
ATOM   5774  C CB  . GLN A 1 786 ? 188.746 217.989 205.035 1.00 119.08 ? 818  GLN B CB  1 
ATOM   5775  C CG  . GLN A 1 786 ? 187.658 217.413 204.160 1.00 119.08 ? 818  GLN B CG  1 
ATOM   5776  C CD  . GLN A 1 786 ? 188.177 216.241 203.397 1.00 119.08 ? 818  GLN B CD  1 
ATOM   5777  O OE1 . GLN A 1 786 ? 189.291 216.274 202.858 1.00 119.08 ? 818  GLN B OE1 1 
ATOM   5778  N NE2 . GLN A 1 786 ? 187.414 215.178 203.366 1.00 119.08 ? 818  GLN B NE2 1 
ATOM   5779  N N   . THR A 1 787 ? 190.372 220.302 206.576 1.00 89.30  ? 819  THR B N   1 
ATOM   5780  C CA  . THR A 1 787 ? 191.408 220.568 207.543 1.00 89.30  ? 819  THR B CA  1 
ATOM   5781  C C   . THR A 1 787 ? 190.827 221.331 208.708 1.00 89.30  ? 819  THR B C   1 
ATOM   5782  O O   . THR A 1 787 ? 191.106 220.977 209.860 1.00 89.30  ? 819  THR B O   1 
ATOM   5783  C CB  . THR A 1 787 ? 192.603 221.361 206.984 1.00 122.24 ? 819  THR B CB  1 
ATOM   5784  O OG1 . THR A 1 787 ? 193.216 220.651 205.891 1.00 122.24 ? 819  THR B OG1 1 
ATOM   5785  C CG2 . THR A 1 787 ? 193.644 221.470 208.111 1.00 122.24 ? 819  THR B CG2 1 
ATOM   5786  N N   . THR A 1 788 ? 189.987 222.348 208.438 1.00 91.29  ? 820  THR B N   1 
ATOM   5787  C CA  . THR A 1 788 ? 189.455 223.112 209.542 1.00 91.29  ? 820  THR B CA  1 
ATOM   5788  C C   . THR A 1 788 ? 188.387 222.319 210.274 1.00 91.29  ? 820  THR B C   1 
ATOM   5789  O O   . THR A 1 788 ? 188.211 222.472 211.480 1.00 91.29  ? 820  THR B O   1 
ATOM   5790  C CB  . THR A 1 788 ? 188.889 224.480 209.109 1.00 124.97 ? 820  THR B CB  1 
ATOM   5791  O OG1 . THR A 1 788 ? 187.823 224.287 208.178 1.00 124.97 ? 820  THR B OG1 1 
ATOM   5792  C CG2 . THR A 1 788 ? 190.013 225.348 208.466 1.00 124.97 ? 820  THR B CG2 1 
ATOM   5793  N N   . THR A 1 789 ? 187.729 221.388 209.603 1.00 91.01  ? 821  THR B N   1 
ATOM   5794  C CA  . THR A 1 789 ? 186.755 220.567 210.292 1.00 91.01  ? 821  THR B CA  1 
ATOM   5795  C C   . THR A 1 789 ? 187.471 219.805 211.399 1.00 91.01  ? 821  THR B C   1 
ATOM   5796  O O   . THR A 1 789 ? 186.974 219.709 212.535 1.00 91.01  ? 821  THR B O   1 
ATOM   5797  C CB  . THR A 1 789 ? 186.092 219.579 209.323 1.00 124.58 ? 821  THR B CB  1 
ATOM   5798  O OG1 . THR A 1 789 ? 185.373 220.305 208.321 1.00 124.58 ? 821  THR B OG1 1 
ATOM   5799  C CG2 . THR A 1 789 ? 185.161 218.651 210.047 1.00 124.58 ? 821  THR B CG2 1 
ATOM   5800  N N   . LEU A 1 790 ? 188.640 219.257 211.061 1.00 91.28  ? 822  LEU B N   1 
ATOM   5801  C CA  . LEU A 1 790 ? 189.426 218.507 212.012 1.00 91.28  ? 822  LEU B CA  1 
ATOM   5802  C C   . LEU A 1 790 ? 190.011 219.408 213.085 1.00 91.28  ? 822  LEU B C   1 
ATOM   5803  O O   . LEU A 1 790 ? 189.989 219.052 214.270 1.00 91.28  ? 822  LEU B O   1 
ATOM   5804  C CB  . LEU A 1 790 ? 190.523 217.715 211.278 1.00 129.74 ? 822  LEU B CB  1 
ATOM   5805  C CG  . LEU A 1 790 ? 191.410 216.753 212.122 1.00 129.74 ? 822  LEU B CG  1 
ATOM   5806  C CD1 . LEU A 1 790 ? 190.588 215.737 212.872 1.00 129.74 ? 822  LEU B CD1 1 
ATOM   5807  C CD2 . LEU A 1 790 ? 192.347 216.016 211.175 1.00 129.74 ? 822  LEU B CD2 1 
ATOM   5808  N N   . THR A 1 791 ? 190.489 220.597 212.711 1.00 93.02  ? 823  THR B N   1 
ATOM   5809  C CA  . THR A 1 791 ? 191.053 221.446 213.736 1.00 93.02  ? 823  THR B CA  1 
ATOM   5810  C C   . THR A 1 791 ? 190.007 221.876 214.718 1.00 93.02  ? 823  THR B C   1 
ATOM   5811  O O   . THR A 1 791 ? 190.267 221.933 215.923 1.00 93.02  ? 823  THR B O   1 
ATOM   5812  C CB  . THR A 1 791 ? 191.618 222.766 213.184 1.00 127.33 ? 823  THR B CB  1 
ATOM   5813  O OG1 . THR A 1 791 ? 190.601 223.441 212.481 1.00 127.33 ? 823  THR B OG1 1 
ATOM   5814  C CG2 . THR A 1 791 ? 192.798 222.567 212.322 1.00 127.33 ? 823  THR B CG2 1 
ATOM   5815  N N   . VAL A 1 792 ? 188.804 222.133 214.223 1.00 94.10  ? 824  VAL B N   1 
ATOM   5816  C CA  . VAL A 1 792 ? 187.772 222.608 215.095 1.00 94.10  ? 824  VAL B CA  1 
ATOM   5817  C C   . VAL A 1 792 ? 187.348 221.556 216.087 1.00 94.10  ? 824  VAL B C   1 
ATOM   5818  O O   . VAL A 1 792 ? 187.299 221.868 217.274 1.00 94.10  ? 824  VAL B O   1 
ATOM   5819  C CB  . VAL A 1 792 ? 186.583 223.171 214.289 1.00 132.51 ? 824  VAL B CB  1 
ATOM   5820  C CG1 . VAL A 1 792 ? 185.411 223.476 215.204 1.00 132.51 ? 824  VAL B CG1 1 
ATOM   5821  C CG2 . VAL A 1 792 ? 187.022 224.488 213.602 1.00 132.51 ? 824  VAL B CG2 1 
ATOM   5822  N N   . SER A 1 793 ? 187.102 220.310 215.678 1.00 93.50  ? 825  SER B N   1 
ATOM   5823  C CA  . SER A 1 793 ? 186.692 219.376 216.722 1.00 93.50  ? 825  SER B CA  1 
ATOM   5824  C C   . SER A 1 793 ? 187.801 219.082 217.727 1.00 93.50  ? 825  SER B C   1 
ATOM   5825  O O   . SER A 1 793 ? 187.516 218.896 218.912 1.00 93.50  ? 825  SER B O   1 
ATOM   5826  C CB  . SER A 1 793 ? 186.107 218.080 216.185 1.00 124.54 ? 825  SER B CB  1 
ATOM   5827  O OG  . SER A 1 793 ? 184.848 218.290 215.585 1.00 124.54 ? 825  SER B OG  1 
ATOM   5828  N N   . VAL A 1 794 ? 189.067 219.035 217.304 1.00 93.66  ? 826  VAL B N   1 
ATOM   5829  C CA  . VAL A 1 794 ? 190.100 218.747 218.292 1.00 93.66  ? 826  VAL B CA  1 
ATOM   5830  C C   . VAL A 1 794 ? 190.234 219.896 219.295 1.00 93.66  ? 826  VAL B C   1 
ATOM   5831  O O   . VAL A 1 794 ? 190.335 219.651 220.508 1.00 93.66  ? 826  VAL B O   1 
ATOM   5832  C CB  . VAL A 1 794 ? 191.434 218.390 217.618 1.00 131.89 ? 826  VAL B CB  1 
ATOM   5833  C CG1 . VAL A 1 794 ? 192.580 218.286 218.669 1.00 131.89 ? 826  VAL B CG1 1 
ATOM   5834  C CG2 . VAL A 1 794 ? 191.274 217.062 216.886 1.00 131.89 ? 826  VAL B CG2 1 
ATOM   5835  N N   . SER A 1 795 ? 190.216 221.141 218.808 1.00 94.98  ? 827  SER B N   1 
ATOM   5836  C CA  . SER A 1 795 ? 190.315 222.274 219.704 1.00 94.98  ? 827  SER B CA  1 
ATOM   5837  C C   . SER A 1 795 ? 189.087 222.349 220.597 1.00 94.98  ? 827  SER B C   1 
ATOM   5838  O O   . SER A 1 795 ? 189.195 222.662 221.785 1.00 94.98  ? 827  SER B O   1 
ATOM   5839  C CB  . SER A 1 795 ? 190.418 223.584 218.929 1.00 126.51 ? 827  SER B CB  1 
ATOM   5840  O OG  . SER A 1 795 ? 191.635 223.724 218.221 1.00 126.51 ? 827  SER B OG  1 
ATOM   5841  N N   . LEU A 1 796 ? 187.906 222.058 220.055 1.00 94.88  ? 828  LEU B N   1 
ATOM   5842  C CA  . LEU A 1 796 ? 186.732 222.130 220.885 1.00 94.88  ? 828  LEU B CA  1 
ATOM   5843  C C   . LEU A 1 796 ? 186.740 221.085 221.964 1.00 94.88  ? 828  LEU B C   1 
ATOM   5844  O O   . LEU A 1 796 ? 186.395 221.395 223.096 1.00 94.88  ? 828  LEU B O   1 
ATOM   5845  C CB  . LEU A 1 796 ? 185.467 221.985 220.064 1.00 134.86 ? 828  LEU B CB  1 
ATOM   5846  C CG  . LEU A 1 796 ? 185.064 223.122 219.146 1.00 134.86 ? 828  LEU B CG  1 
ATOM   5847  C CD1 . LEU A 1 796 ? 183.905 222.631 218.309 1.00 134.86 ? 828  LEU B CD1 1 
ATOM   5848  C CD2 . LEU A 1 796 ? 184.654 224.346 219.945 1.00 134.86 ? 828  LEU B CD2 1 
ATOM   5849  N N   . SER A 1 797 ? 187.202 219.876 221.682 1.00 93.90  ? 829  SER B N   1 
ATOM   5850  C CA  . SER A 1 797 ? 187.212 218.876 222.731 1.00 93.90  ? 829  SER B CA  1 
ATOM   5851  C C   . SER A 1 797 ? 188.123 219.326 223.867 1.00 93.90  ? 829  SER B C   1 
ATOM   5852  O O   . SER A 1 797 ? 187.809 219.136 225.052 1.00 93.90  ? 829  SER B O   1 
ATOM   5853  C CB  . SER A 1 797 ? 187.693 217.557 222.172 1.00 125.07 ? 829  SER B CB  1 
ATOM   5854  O OG  . SER A 1 797 ? 186.771 217.029 221.251 1.00 125.07 ? 829  SER B OG  1 
ATOM   5855  N N   . ALA A 1 798 ? 189.255 219.940 223.512 1.00 95.63  ? 830  ALA B N   1 
ATOM   5856  C CA  . ALA A 1 798 ? 190.182 220.443 224.504 1.00 95.63  ? 830  ALA B CA  1 
ATOM   5857  C C   . ALA A 1 798 ? 189.519 221.519 225.356 1.00 95.63  ? 830  ALA B C   1 
ATOM   5858  O O   . ALA A 1 798 ? 189.657 221.529 226.588 1.00 95.63  ? 830  ALA B O   1 
ATOM   5859  C CB  . ALA A 1 798 ? 191.375 220.977 223.781 1.00 129.19 ? 830  ALA B CB  1 
ATOM   5860  N N   . SER A 1 799 ? 188.724 222.363 224.692 1.00 95.91  ? 831  SER B N   1 
ATOM   5861  C CA  . SER A 1 799 ? 187.962 223.429 225.318 1.00 95.91  ? 831  SER B CA  1 
ATOM   5862  C C   . SER A 1 799 ? 186.924 222.865 226.261 1.00 95.91  ? 831  SER B C   1 
ATOM   5863  O O   . SER A 1 799 ? 186.733 223.394 227.360 1.00 95.91  ? 831  SER B O   1 
ATOM   5864  C CB  . SER A 1 799 ? 187.297 224.302 224.275 1.00 127.75 ? 831  SER B CB  1 
ATOM   5865  O OG  . SER A 1 799 ? 186.587 225.346 224.875 1.00 127.75 ? 831  SER B OG  1 
ATOM   5866  N N   . VAL A 1 800 ? 186.266 221.778 225.857 1.00 95.45  ? 832  VAL B N   1 
ATOM   5867  C CA  . VAL A 1 800 ? 185.240 221.182 226.689 1.00 95.45  ? 832  VAL B CA  1 
ATOM   5868  C C   . VAL A 1 800 ? 185.873 220.719 227.989 1.00 95.45  ? 832  VAL B C   1 
ATOM   5869  O O   . VAL A 1 800 ? 185.323 220.975 229.071 1.00 95.45  ? 832  VAL B O   1 
ATOM   5870  C CB  . VAL A 1 800 ? 184.554 219.982 225.981 1.00 134.42 ? 832  VAL B CB  1 
ATOM   5871  C CG1 . VAL A 1 800 ? 183.640 219.263 226.949 1.00 134.42 ? 832  VAL B CG1 1 
ATOM   5872  C CG2 . VAL A 1 800 ? 183.736 220.456 224.788 1.00 134.42 ? 832  VAL B CG2 1 
ATOM   5873  N N   . SER A 1 801 ? 187.028 220.062 227.895 1.00 93.77  ? 833  SER B N   1 
ATOM   5874  C CA  . SER A 1 801 ? 187.688 219.583 229.091 1.00 93.77  ? 833  SER B CA  1 
ATOM   5875  C C   . SER A 1 801 ? 188.044 220.742 230.000 1.00 93.77  ? 833  SER B C   1 
ATOM   5876  O O   . SER A 1 801 ? 187.781 220.708 231.207 1.00 93.77  ? 833  SER B O   1 
ATOM   5877  C CB  . SER A 1 801 ? 188.927 218.806 228.735 1.00 124.90 ? 833  SER B CB  1 
ATOM   5878  O OG  . SER A 1 801 ? 189.549 218.311 229.888 1.00 124.90 ? 833  SER B OG  1 
ATOM   5879  N N   . LEU A 1 802 ? 188.590 221.820 229.441 1.00 95.65  ? 834  LEU B N   1 
ATOM   5880  C CA  . LEU A 1 802 ? 188.910 222.920 230.322 1.00 95.65  ? 834  LEU B CA  1 
ATOM   5881  C C   . LEU A 1 802 ? 187.667 223.551 230.932 1.00 95.65  ? 834  LEU B C   1 
ATOM   5882  O O   . LEU A 1 802 ? 187.622 223.824 232.137 1.00 95.65  ? 834  LEU B O   1 
ATOM   5883  C CB  . LEU A 1 802 ? 189.664 224.021 229.576 1.00 135.95 ? 834  LEU B CB  1 
ATOM   5884  C CG  . LEU A 1 802 ? 191.083 223.738 229.117 1.00 135.95 ? 834  LEU B CG  1 
ATOM   5885  C CD1 . LEU A 1 802 ? 191.560 224.898 228.221 1.00 135.95 ? 834  LEU B CD1 1 
ATOM   5886  C CD2 . LEU A 1 802 ? 192.029 223.609 230.338 1.00 135.95 ? 834  LEU B CD2 1 
ATOM   5887  N N   . GLY A 1 803 ? 186.604 223.704 230.151 1.00 93.13  ? 835  GLY B N   1 
ATOM   5888  C CA  . GLY A 1 803 ? 185.420 224.377 230.655 1.00 93.13  ? 835  GLY B CA  1 
ATOM   5889  C C   . GLY A 1 803 ? 184.799 223.716 231.879 1.00 93.13  ? 835  GLY B C   1 
ATOM   5890  O O   . GLY A 1 803 ? 184.303 224.413 232.767 1.00 93.13  ? 835  GLY B O   1 
ATOM   5891  N N   . MET A 1 804 ? 184.785 222.383 231.927 1.00 91.49  ? 836  MET B N   1 
ATOM   5892  C CA  . MET A 1 804 ? 184.210 221.715 233.092 1.00 91.49  ? 836  MET B CA  1 
ATOM   5893  C C   . MET A 1 804 ? 185.201 221.298 234.174 1.00 91.49  ? 836  MET B C   1 
ATOM   5894  O O   . MET A 1 804 ? 184.841 221.261 235.352 1.00 91.49  ? 836  MET B O   1 
ATOM   5895  C CB  . MET A 1 804 ? 183.418 220.498 232.677 1.00 127.28 ? 836  MET B CB  1 
ATOM   5896  C CG  . MET A 1 804 ? 182.164 220.774 231.877 1.00 127.28 ? 836  MET B CG  1 
ATOM   5897  S SD  . MET A 1 804 ? 180.985 221.875 232.738 1.00 127.28 ? 836  MET B SD  1 
ATOM   5898  C CE  . MET A 1 804 ? 180.439 220.915 234.159 1.00 127.28 ? 836  MET B CE  1 
ATOM   5899  N N   . LEU A 1 805 ? 186.424 220.930 233.795 1.00 91.51  ? 837  LEU B N   1 
ATOM   5900  C CA  . LEU A 1 805 ? 187.379 220.407 234.758 1.00 91.51  ? 837  LEU B CA  1 
ATOM   5901  C C   . LEU A 1 805 ? 188.400 221.399 235.279 1.00 91.51  ? 837  LEU B C   1 
ATOM   5902  O O   . LEU A 1 805 ? 189.004 221.154 236.325 1.00 91.51  ? 837  LEU B O   1 
ATOM   5903  C CB  . LEU A 1 805 ? 188.115 219.223 234.123 1.00 130.07 ? 837  LEU B CB  1 
ATOM   5904  C CG  . LEU A 1 805 ? 187.230 218.039 233.691 1.00 130.07 ? 837  LEU B CG  1 
ATOM   5905  C CD1 . LEU A 1 805 ? 188.083 217.024 232.956 1.00 130.07 ? 837  LEU B CD1 1 
ATOM   5906  C CD2 . LEU A 1 805 ? 186.576 217.372 234.902 1.00 130.07 ? 837  LEU B CD2 1 
ATOM   5907  N N   . TYR A 1 806 ? 188.660 222.480 234.549 1.00 92.91  ? 838  TYR B N   1 
ATOM   5908  C CA  . TYR A 1 806 ? 189.716 223.374 234.967 1.00 92.91  ? 838  TYR B CA  1 
ATOM   5909  C C   . TYR A 1 806 ? 189.344 224.819 235.156 1.00 92.91  ? 838  TYR B C   1 
ATOM   5910  O O   . TYR A 1 806 ? 189.580 225.382 236.217 1.00 92.91  ? 838  TYR B O   1 
ATOM   5911  C CB  . TYR A 1 806 ? 190.845 223.272 233.982 1.00 124.71 ? 838  TYR B CB  1 
ATOM   5912  C CG  . TYR A 1 806 ? 191.489 221.927 234.020 1.00 124.71 ? 838  TYR B CG  1 
ATOM   5913  C CD1 . TYR A 1 806 ? 192.351 221.706 235.031 1.00 124.71 ? 838  TYR B CD1 1 
ATOM   5914  C CD2 . TYR A 1 806 ? 191.223 220.916 233.096 1.00 124.71 ? 838  TYR B CD2 1 
ATOM   5915  C CE1 . TYR A 1 806 ? 192.965 220.525 235.174 1.00 124.71 ? 838  TYR B CE1 1 
ATOM   5916  C CE2 . TYR A 1 806 ? 191.853 219.701 233.236 1.00 124.71 ? 838  TYR B CE2 1 
ATOM   5917  C CZ  . TYR A 1 806 ? 192.730 219.529 234.299 1.00 124.71 ? 838  TYR B CZ  1 
ATOM   5918  O OH  . TYR A 1 806 ? 193.359 218.368 234.503 1.00 124.71 ? 838  TYR B OH  1 
ATOM   5919  N N   . MET A 1 807 ? 188.721 225.433 234.174 1.00 89.81  ? 839  MET B N   1 
ATOM   5920  C CA  . MET A 1 807 ? 188.443 226.858 234.269 1.00 89.81  ? 839  MET B CA  1 
ATOM   5921  C C   . MET A 1 807 ? 187.784 227.313 235.587 1.00 89.81  ? 839  MET B C   1 
ATOM   5922  O O   . MET A 1 807 ? 188.302 228.248 236.209 1.00 89.81  ? 839  MET B O   1 
ATOM   5923  C CB  . MET A 1 807 ? 187.654 227.324 233.051 1.00 124.95 ? 839  MET B CB  1 
ATOM   5924  C CG  . MET A 1 807 ? 188.465 227.343 231.792 1.00 124.95 ? 839  MET B CG  1 
ATOM   5925  S SD  . MET A 1 807 ? 187.502 227.817 230.351 1.00 124.95 ? 839  MET B SD  1 
ATOM   5926  C CE  . MET A 1 807 ? 188.748 227.776 229.062 1.00 124.95 ? 839  MET B CE  1 
ATOM   5927  N N   . PRO A 1 808 ? 186.659 226.722 236.059 1.00 89.37  ? 840  PRO B N   1 
ATOM   5928  C CA  . PRO A 1 808 ? 186.005 227.114 237.294 1.00 89.37  ? 840  PRO B CA  1 
ATOM   5929  C C   . PRO A 1 808 ? 186.809 226.732 238.527 1.00 89.37  ? 840  PRO B C   1 
ATOM   5930  O O   . PRO A 1 808 ? 186.556 227.241 239.625 1.00 89.37  ? 840  PRO B O   1 
ATOM   5931  C CB  . PRO A 1 808 ? 184.676 226.347 237.236 1.00 152.71 ? 840  PRO B CB  1 
ATOM   5932  C CG  . PRO A 1 808 ? 184.957 225.139 236.366 1.00 152.71 ? 840  PRO B CG  1 
ATOM   5933  C CD  . PRO A 1 808 ? 185.948 225.613 235.336 1.00 152.71 ? 840  PRO B CD  1 
ATOM   5934  N N   . LYS A 1 809 ? 187.768 225.822 238.360 1.00 88.95  ? 841  LYS B N   1 
ATOM   5935  C CA  . LYS A 1 809 ? 188.513 225.370 239.497 1.00 88.95  ? 841  LYS B CA  1 
ATOM   5936  C C   . LYS A 1 809 ? 189.634 226.335 239.668 1.00 88.95  ? 841  LYS B C   1 
ATOM   5937  O O   . LYS A 1 809 ? 189.940 226.712 240.787 1.00 88.95  ? 841  LYS B O   1 
ATOM   5938  C CB  . LYS A 1 809 ? 189.032 223.953 239.285 1.00 127.24 ? 841  LYS B CB  1 
ATOM   5939  C CG  . LYS A 1 809 ? 187.926 222.894 239.019 1.00 127.24 ? 841  LYS B CG  1 
ATOM   5940  C CD  . LYS A 1 809 ? 186.801 222.872 240.072 1.00 127.24 ? 841  LYS B CD  1 
ATOM   5941  C CE  . LYS A 1 809 ? 187.277 222.414 241.449 1.00 127.24 ? 841  LYS B CE  1 
ATOM   5942  N NZ  . LYS A 1 809 ? 186.141 222.298 242.406 1.00 127.24 ? 841  LYS B NZ  1 
ATOM   5943  N N   . VAL A 1 810 ? 190.166 226.806 238.550 1.00 90.64  ? 842  VAL B N   1 
ATOM   5944  C CA  . VAL A 1 810 ? 191.226 227.781 238.533 1.00 90.64  ? 842  VAL B CA  1 
ATOM   5945  C C   . VAL A 1 810 ? 190.716 229.055 239.091 1.00 90.64  ? 842  VAL B C   1 
ATOM   5946  O O   . VAL A 1 810 ? 191.381 229.683 239.907 1.00 90.64  ? 842  VAL B O   1 
ATOM   5947  C CB  . VAL A 1 810 ? 191.779 227.969 237.130 1.00 127.64 ? 842  VAL B CB  1 
ATOM   5948  C CG1 . VAL A 1 810 ? 192.721 229.166 237.035 1.00 127.64 ? 842  VAL B CG1 1 
ATOM   5949  C CG2 . VAL A 1 810 ? 192.536 226.764 236.831 1.00 127.64 ? 842  VAL B CG2 1 
ATOM   5950  N N   . TYR A 1 811 ? 189.508 229.450 238.707 1.00 90.14  ? 843  TYR B N   1 
ATOM   5951  C CA  . TYR A 1 811 ? 189.008 230.669 239.288 1.00 90.14  ? 843  TYR B CA  1 
ATOM   5952  C C   . TYR A 1 811 ? 189.095 230.579 240.808 1.00 90.14  ? 843  TYR B C   1 
ATOM   5953  O O   . TYR A 1 811 ? 189.655 231.465 241.451 1.00 90.14  ? 843  TYR B O   1 
ATOM   5954  C CB  . TYR A 1 811 ? 187.579 230.983 238.860 1.00 120.99 ? 843  TYR B CB  1 
ATOM   5955  C CG  . TYR A 1 811 ? 187.091 232.174 239.613 1.00 120.99 ? 843  TYR B CG  1 
ATOM   5956  C CD1 . TYR A 1 811 ? 187.492 233.452 239.253 1.00 120.99 ? 843  TYR B CD1 1 
ATOM   5957  C CD2 . TYR A 1 811 ? 186.284 231.987 240.694 1.00 120.99 ? 843  TYR B CD2 1 
ATOM   5958  C CE1 . TYR A 1 811 ? 187.096 234.528 240.007 1.00 120.99 ? 843  TYR B CE1 1 
ATOM   5959  C CE2 . TYR A 1 811 ? 185.890 233.044 241.433 1.00 120.99 ? 843  TYR B CE2 1 
ATOM   5960  C CZ  . TYR A 1 811 ? 186.295 234.311 241.110 1.00 120.99 ? 843  TYR B CZ  1 
ATOM   5961  O OH  . TYR A 1 811 ? 185.935 235.356 241.920 1.00 120.99 ? 843  TYR B OH  1 
ATOM   5962  N N   . ILE A 1 812 ? 188.603 229.503 241.400 1.00 87.37  ? 844  ILE B N   1 
ATOM   5963  C CA  . ILE A 1 812 ? 188.704 229.421 242.844 1.00 87.37  ? 844  ILE B CA  1 
ATOM   5964  C C   . ILE A 1 812 ? 190.154 229.278 243.330 1.00 87.37  ? 844  ILE B C   1 
ATOM   5965  O O   . ILE A 1 812 ? 190.581 230.002 244.229 1.00 87.37  ? 844  ILE B O   1 
ATOM   5966  C CB  . ILE A 1 812 ? 187.841 228.268 243.386 1.00 124.18 ? 844  ILE B CB  1 
ATOM   5967  C CG1 . ILE A 1 812 ? 186.317 228.529 243.072 1.00 124.18 ? 844  ILE B CG1 1 
ATOM   5968  C CG2 . ILE A 1 812 ? 188.071 228.070 244.894 1.00 124.18 ? 844  ILE B CG2 1 
ATOM   5969  C CD1 . ILE A 1 812 ? 185.705 229.814 243.666 1.00 124.18 ? 844  ILE B CD1 1 
ATOM   5970  N N   . ILE A 1 813 ? 190.966 228.451 242.682 1.00 87.36  ? 845  ILE B N   1 
ATOM   5971  C CA  . ILE A 1 813 ? 192.322 228.230 243.169 1.00 87.36  ? 845  ILE B CA  1 
ATOM   5972  C C   . ILE A 1 813 ? 193.105 229.535 243.216 1.00 87.36  ? 845  ILE B C   1 
ATOM   5973  O O   . ILE A 1 813 ? 193.789 229.826 244.205 1.00 87.36  ? 845  ILE B O   1 
ATOM   5974  C CB  . ILE A 1 813 ? 193.100 227.254 242.246 1.00 124.17 ? 845  ILE B CB  1 
ATOM   5975  C CG1 . ILE A 1 813 ? 192.526 225.848 242.295 1.00 124.17 ? 845  ILE B CG1 1 
ATOM   5976  C CG2 . ILE A 1 813 ? 194.544 227.193 242.735 1.00 124.17 ? 845  ILE B CG2 1 
ATOM   5977  C CD1 . ILE A 1 813 ? 192.993 224.918 241.171 1.00 124.17 ? 845  ILE B CD1 1 
ATOM   5978  N N   . LEU A 1 814 ? 193.007 230.313 242.147 1.00 88.68  ? 846  LEU B N   1 
ATOM   5979  C CA  . LEU A 1 814 ? 193.732 231.557 242.023 1.00 88.68  ? 846  LEU B CA  1 
ATOM   5980  C C   . LEU A 1 814 ? 193.110 232.753 242.758 1.00 88.68  ? 846  LEU B C   1 
ATOM   5981  O O   . LEU A 1 814 ? 193.842 233.594 243.286 1.00 88.68  ? 846  LEU B O   1 
ATOM   5982  C CB  . LEU A 1 814 ? 193.858 231.900 240.536 1.00 126.05 ? 846  LEU B CB  1 
ATOM   5983  C CG  . LEU A 1 814 ? 194.702 233.137 240.150 1.00 126.05 ? 846  LEU B CG  1 
ATOM   5984  C CD1 . LEU A 1 814 ? 196.164 232.960 240.637 1.00 126.05 ? 846  LEU B CD1 1 
ATOM   5985  C CD2 . LEU A 1 814 ? 194.657 233.289 238.623 1.00 126.05 ? 846  LEU B CD2 1 
ATOM   5986  N N   . PHE A 1 815 ? 191.774 232.876 242.773 1.00 89.53  ? 847  PHE B N   1 
ATOM   5987  C CA  . PHE A 1 815 ? 191.160 234.062 243.362 1.00 89.53  ? 847  PHE B CA  1 
ATOM   5988  C C   . PHE A 1 815 ? 190.554 233.893 244.753 1.00 89.53  ? 847  PHE B C   1 
ATOM   5989  O O   . PHE A 1 815 ? 190.245 234.897 245.398 1.00 89.53  ? 847  PHE B O   1 
ATOM   5990  C CB  . PHE A 1 815 ? 190.093 234.604 242.416 1.00 121.08 ? 847  PHE B CB  1 
ATOM   5991  C CG  . PHE A 1 815 ? 190.670 235.088 241.113 1.00 121.08 ? 847  PHE B CG  1 
ATOM   5992  C CD1 . PHE A 1 815 ? 191.210 236.355 240.985 1.00 121.08 ? 847  PHE B CD1 1 
ATOM   5993  C CD2 . PHE A 1 815 ? 190.668 234.273 240.014 1.00 121.08 ? 847  PHE B CD2 1 
ATOM   5994  C CE1 . PHE A 1 815 ? 191.732 236.776 239.775 1.00 121.08 ? 847  PHE B CE1 1 
ATOM   5995  C CE2 . PHE A 1 815 ? 191.177 234.676 238.813 1.00 121.08 ? 847  PHE B CE2 1 
ATOM   5996  C CZ  . PHE A 1 815 ? 191.714 235.930 238.686 1.00 121.08 ? 847  PHE B CZ  1 
ATOM   5997  N N   . HIS A 1 816 ? 190.418 232.664 245.255 1.00 86.86  ? 848  HIS B N   1 
ATOM   5998  C CA  . HIS A 1 816 ? 189.813 232.440 246.563 1.00 86.86  ? 848  HIS B CA  1 
ATOM   5999  C C   . HIS A 1 816 ? 190.595 231.522 247.496 1.00 86.86  ? 848  HIS B C   1 
ATOM   6000  O O   . HIS A 1 816 ? 190.146 230.410 247.758 1.00 86.86  ? 848  HIS B O   1 
ATOM   6001  C CB  . HIS A 1 816 ? 188.419 231.883 246.376 1.00 115.37 ? 848  HIS B CB  1 
ATOM   6002  C CG  . HIS A 1 816 ? 187.515 232.842 245.789 1.00 115.37 ? 848  HIS B CG  1 
ATOM   6003  N ND1 . HIS A 1 816 ? 186.835 233.749 246.554 1.00 115.37 ? 848  HIS B ND1 1 
ATOM   6004  C CD2 . HIS A 1 816 ? 187.191 233.094 244.519 1.00 115.37 ? 848  HIS B CD2 1 
ATOM   6005  C CE1 . HIS A 1 816 ? 186.099 234.516 245.776 1.00 115.37 ? 848  HIS B CE1 1 
ATOM   6006  N NE2 . HIS A 1 816 ? 186.286 234.147 244.522 1.00 115.37 ? 848  HIS B NE2 1 
ATOM   6007  N N   . PRO A 1 817 ? 191.735 231.965 248.068 1.00 81.32  ? 849  PRO B N   1 
ATOM   6008  C CA  . PRO A 1 817 ? 192.615 231.185 248.923 1.00 81.32  ? 849  PRO B CA  1 
ATOM   6009  C C   . PRO A 1 817 ? 191.897 230.543 250.108 1.00 81.32  ? 849  PRO B C   1 
ATOM   6010  O O   . PRO A 1 817 ? 192.295 229.469 250.565 1.00 81.32  ? 849  PRO B O   1 
ATOM   6011  C CB  . PRO A 1 817 ? 193.612 232.240 249.423 1.00 138.96 ? 849  PRO B CB  1 
ATOM   6012  C CG  . PRO A 1 817 ? 193.632 233.285 248.345 1.00 138.96 ? 849  PRO B CG  1 
ATOM   6013  C CD  . PRO A 1 817 ? 192.203 233.352 247.849 1.00 138.96 ? 849  PRO B CD  1 
ATOM   6014  N N   . GLU A 1 818 ? 190.796 231.149 250.580 1.00 77.75  ? 850  GLU B N   1 
ATOM   6015  C CA  . GLU A 1 818 ? 190.079 230.603 251.722 1.00 77.75  ? 850  GLU B CA  1 
ATOM   6016  C C   . GLU A 1 818 ? 189.360 229.309 251.355 1.00 77.75  ? 850  GLU B C   1 
ATOM   6017  O O   . GLU A 1 818 ? 188.901 228.570 252.226 1.00 77.75  ? 850  GLU B O   1 
ATOM   6018  C CB  . GLU A 1 818 ? 189.066 231.635 252.254 1.00 102.47 ? 850  GLU B CB  1 
ATOM   6019  C CG  . GLU A 1 818 ? 187.818 231.864 251.371 1.00 102.47 ? 850  GLU B CG  1 
ATOM   6020  C CD  . GLU A 1 818 ? 188.020 232.822 250.210 1.00 102.47 ? 850  GLU B CD  1 
ATOM   6021  O OE1 . GLU A 1 818 ? 189.125 233.321 250.081 1.00 102.47 ? 850  GLU B OE1 1 
ATOM   6022  O OE2 . GLU A 1 818 ? 187.073 233.038 249.436 1.00 102.47 ? 850  GLU B OE2 1 
ATOM   6023  N N   . GLN A 1 819 ? 189.229 229.060 250.056 1.00 76.63  ? 851  GLN B N   1 
ATOM   6024  C CA  . GLN A 1 819 ? 188.558 227.902 249.526 1.00 76.63  ? 851  GLN B CA  1 
ATOM   6025  C C   . GLN A 1 819 ? 189.565 226.884 249.031 1.00 76.63  ? 851  GLN B C   1 
ATOM   6026  O O   . GLN A 1 819 ? 189.183 225.890 248.406 1.00 76.63  ? 851  GLN B O   1 
ATOM   6027  C CB  . GLN A 1 819 ? 187.614 228.301 248.390 1.00 104.15 ? 851  GLN B CB  1 
ATOM   6028  C CG  . GLN A 1 819 ? 186.504 229.223 248.820 1.00 104.15 ? 851  GLN B CG  1 
ATOM   6029  C CD  . GLN A 1 819 ? 185.557 229.621 247.736 1.00 104.15 ? 851  GLN B CD  1 
ATOM   6030  O OE1 . GLN A 1 819 ? 185.080 228.793 246.953 1.00 104.15 ? 851  GLN B OE1 1 
ATOM   6031  N NE2 . GLN A 1 819 ? 185.266 230.925 247.687 1.00 104.15 ? 851  GLN B NE2 1 
ATOM   6032  N N   . ASN A 1 820 ? 190.860 227.090 249.292 1.00 74.79  ? 852  ASN B N   1 
ATOM   6033  C CA  . ASN A 1 820 ? 191.796 226.110 248.784 1.00 74.79  ? 852  ASN B CA  1 
ATOM   6034  C C   . ASN A 1 820 ? 191.927 224.945 249.727 1.00 74.79  ? 852  ASN B C   1 
ATOM   6035  O O   . ASN A 1 820 ? 192.827 224.845 250.563 1.00 74.79  ? 852  ASN B O   1 
ATOM   6036  C CB  . ASN A 1 820 ? 193.116 226.712 248.404 1.00 99.48  ? 852  ASN B CB  1 
ATOM   6037  C CG  . ASN A 1 820 ? 192.963 227.553 247.183 1.00 99.48  ? 852  ASN B CG  1 
ATOM   6038  O OD1 . ASN A 1 820 ? 191.964 227.406 246.486 1.00 99.48  ? 852  ASN B OD1 1 
ATOM   6039  N ND2 . ASN A 1 820 ? 193.923 228.373 246.889 1.00 99.48  ? 852  ASN B ND2 1 
ATOM   6040  N N   . VAL A 1 821 ? 190.974 224.061 249.535 1.00 75.68  ? 853  VAL B N   1 
ATOM   6041  C CA  . VAL A 1 821 ? 190.727 222.868 250.310 1.00 75.68  ? 853  VAL B CA  1 
ATOM   6042  C C   . VAL A 1 821 ? 190.691 221.756 249.274 1.00 75.68  ? 853  VAL B C   1 
ATOM   6043  O O   . VAL A 1 821 ? 190.391 222.045 248.117 1.00 75.68  ? 853  VAL B O   1 
ATOM   6044  C CB  . VAL A 1 821 ? 189.354 223.016 251.021 1.00 106.57 ? 853  VAL B CB  1 
ATOM   6045  C CG1 . VAL A 1 821 ? 189.377 224.270 251.892 1.00 106.57 ? 853  VAL B CG1 1 
ATOM   6046  C CG2 . VAL A 1 821 ? 188.210 223.018 249.978 1.00 106.57 ? 853  VAL B CG2 1 
ATOM   6047  N N   . PRO A 1 822 ? 190.822 220.476 249.628 1.00 62.16  ? 854  PRO B N   1 
ATOM   6048  C CA  . PRO A 1 822 ? 190.837 219.366 248.682 1.00 62.16  ? 854  PRO B CA  1 
ATOM   6049  C C   . PRO A 1 822 ? 189.466 218.980 248.073 1.00 62.16  ? 854  PRO B C   1 
ATOM   6050  O O   . PRO A 1 822 ? 188.986 217.859 248.270 1.00 62.16  ? 854  PRO B O   1 
ATOM   6051  C CB  . PRO A 1 822 ? 191.410 218.243 249.568 1.00 106.22 ? 854  PRO B CB  1 
ATOM   6052  C CG  . PRO A 1 822 ? 190.935 218.559 250.951 1.00 106.22 ? 854  PRO B CG  1 
ATOM   6053  C CD  . PRO A 1 822 ? 190.982 220.070 251.045 1.00 106.22 ? 854  PRO B CD  1 
ATOM   6054  N N   . LYS A 1 823 ? 188.881 219.944 247.322 1.00 55.47  ? 855  LYS B N   1 
ATOM   6055  C CA  . LYS A 1 823 ? 187.589 219.930 246.623 1.00 55.47  ? 855  LYS B CA  1 
ATOM   6056  C C   . LYS A 1 823 ? 187.350 221.330 246.064 1.00 55.47  ? 855  LYS B C   1 
ATOM   6057  O O   . LYS A 1 823 ? 187.042 221.494 244.873 1.00 55.47  ? 855  LYS B O   1 
ATOM   6058  C CB  . LYS A 1 823 ? 186.377 219.497 247.531 1.00 79.35  ? 855  LYS B CB  1 
ATOM   6059  C CG  . LYS A 1 823 ? 184.934 219.425 246.779 1.00 79.35  ? 855  LYS B CG  1 
ATOM   6060  C CD  . LYS A 1 823 ? 183.772 218.832 247.685 1.00 79.35  ? 855  LYS B CD  1 
ATOM   6061  C CE  . LYS A 1 823 ? 182.376 218.779 246.927 1.00 79.35  ? 855  LYS B CE  1 
ATOM   6062  N NZ  . LYS A 1 823 ? 181.285 218.159 247.764 1.00 79.35  ? 855  LYS B NZ  1 
ATOM   6063  N N   . LYS B 2 5   ? 191.962 183.216 91.572  1.00 148.14 ? 23   LYS C N   1 
ATOM   6064  C CA  . LYS B 2 5   ? 191.415 183.906 90.401  1.00 24.63  ? 23   LYS C CA  1 
ATOM   6065  C C   . LYS B 2 5   ? 189.871 183.883 90.388  1.00 24.63  ? 23   LYS C C   1 
ATOM   6066  O O   . LYS B 2 5   ? 189.240 184.891 90.034  1.00 24.63  ? 23   LYS C O   1 
ATOM   6067  C CB  . LYS B 2 5   ? 191.987 183.299 89.076  1.00 180.21 ? 23   LYS C CB  1 
ATOM   6068  C CG  . LYS B 2 5   ? 193.544 183.562 88.794  1.00 180.21 ? 23   LYS C CG  1 
ATOM   6069  C CD  . LYS B 2 5   ? 194.039 182.916 87.416  1.00 180.21 ? 23   LYS C CD  1 
ATOM   6070  C CE  . LYS B 2 5   ? 195.575 183.174 87.126  1.00 180.21 ? 23   LYS C CE  1 
ATOM   6071  N NZ  . LYS B 2 5   ? 196.035 182.530 85.836  1.00 180.21 ? 23   LYS C NZ  1 
ATOM   6072  N N   . LYS B 2 6   ? 189.268 182.724 90.735  1.00 40.29  ? 24   LYS C N   1 
ATOM   6073  C CA  . LYS B 2 6   ? 187.820 182.497 90.764  1.00 40.29  ? 24   LYS C CA  1 
ATOM   6074  C C   . LYS B 2 6   ? 187.383 182.487 92.200  1.00 40.29  ? 24   LYS C C   1 
ATOM   6075  O O   . LYS B 2 6   ? 188.127 182.037 93.064  1.00 40.29  ? 24   LYS C O   1 
ATOM   6076  C CB  . LYS B 2 6   ? 187.477 181.178 90.093  1.00 54.65  ? 24   LYS C CB  1 
ATOM   6077  C CG  . LYS B 2 6   ? 187.998 181.043 88.652  1.00 54.65  ? 24   LYS C CG  1 
ATOM   6078  C CD  . LYS B 2 6   ? 187.376 182.072 87.707  1.00 54.65  ? 24   LYS C CD  1 
ATOM   6079  C CE  . LYS B 2 6   ? 187.827 181.851 86.270  1.00 54.65  ? 24   LYS C CE  1 
ATOM   6080  N NZ  . LYS B 2 6   ? 187.271 182.884 85.347  1.00 54.65  ? 24   LYS C NZ  1 
ATOM   6081  N N   . VAL B 2 7   ? 186.183 182.987 92.468  1.00 40.29  ? 25   VAL C N   1 
ATOM   6082  C CA  . VAL B 2 7   ? 185.730 183.019 93.843  1.00 40.29  ? 25   VAL C CA  1 
ATOM   6083  C C   . VAL B 2 7   ? 184.394 182.340 94.068  1.00 40.29  ? 25   VAL C C   1 
ATOM   6084  O O   . VAL B 2 7   ? 183.674 182.658 95.024  1.00 40.29  ? 25   VAL C O   1 
ATOM   6085  C CB  . VAL B 2 7   ? 185.662 184.467 94.338  1.00 56.74  ? 25   VAL C CB  1 
ATOM   6086  C CG1 . VAL B 2 7   ? 187.034 185.054 94.294  1.00 56.74  ? 25   VAL C CG1 1 
ATOM   6087  C CG2 . VAL B 2 7   ? 184.679 185.264 93.548  1.00 56.74  ? 25   VAL C CG2 1 
ATOM   6088  N N   . LEU B 2 8   ? 183.992 181.473 93.141  1.00 40.29  ? 26   LEU C N   1 
ATOM   6089  C CA  . LEU B 2 8   ? 182.683 180.836 93.267  1.00 40.29  ? 26   LEU C CA  1 
ATOM   6090  C C   . LEU B 2 8   ? 181.654 181.915 93.455  1.00 40.29  ? 26   LEU C C   1 
ATOM   6091  O O   . LEU B 2 8   ? 180.816 181.811 94.342  1.00 40.29  ? 26   LEU C O   1 
ATOM   6092  C CB  . LEU B 2 8   ? 182.598 179.935 94.521  1.00 57.27  ? 26   LEU C CB  1 
ATOM   6093  C CG  . LEU B 2 8   ? 183.589 178.807 94.648  1.00 57.27  ? 26   LEU C CG  1 
ATOM   6094  C CD1 . LEU B 2 8   ? 183.462 178.169 96.036  1.00 57.27  ? 26   LEU C CD1 1 
ATOM   6095  C CD2 . LEU B 2 8   ? 183.309 177.763 93.600  1.00 57.27  ? 26   LEU C CD2 1 
ATOM   6096  N N   . THR B 2 9   ? 181.706 182.960 92.648  1.00 40.29  ? 27   THR C N   1 
ATOM   6097  C CA  . THR B 2 9   ? 180.801 184.035 92.900  1.00 40.29  ? 27   THR C CA  1 
ATOM   6098  C C   . THR B 2 9   ? 179.387 183.532 92.882  1.00 40.29  ? 27   THR C C   1 
ATOM   6099  O O   . THR B 2 9   ? 178.958 182.882 91.926  1.00 40.29  ? 27   THR C O   1 
ATOM   6100  C CB  . THR B 2 9   ? 180.905 185.134 91.822  1.00 55.15  ? 27   THR C CB  1 
ATOM   6101  O OG1 . THR B 2 9   ? 182.256 185.595 91.693  1.00 55.15  ? 27   THR C OG1 1 
ATOM   6102  C CG2 . THR B 2 9   ? 180.053 186.317 92.265  1.00 55.15  ? 27   THR C CG2 1 
ATOM   6103  N N   . LEU B 2 10  ? 178.654 183.861 93.925  1.00 40.29  ? 28   LEU C N   1 
ATOM   6104  C CA  . LEU B 2 10  ? 177.254 183.492 93.979  1.00 40.29  ? 28   LEU C CA  1 
ATOM   6105  C C   . LEU B 2 10  ? 176.474 184.776 94.049  1.00 40.29  ? 28   LEU C C   1 
ATOM   6106  O O   . LEU B 2 10  ? 176.918 185.724 94.708  1.00 40.29  ? 28   LEU C O   1 
ATOM   6107  C CB  . LEU B 2 10  ? 176.911 182.631 95.197  1.00 57.27  ? 28   LEU C CB  1 
ATOM   6108  C CG  . LEU B 2 10  ? 177.672 181.339 95.419  1.00 57.27  ? 28   LEU C CG  1 
ATOM   6109  C CD1 . LEU B 2 10  ? 177.188 180.756 96.744  1.00 57.27  ? 28   LEU C CD1 1 
ATOM   6110  C CD2 . LEU B 2 10  ? 177.475 180.364 94.268  1.00 57.27  ? 28   LEU C CD2 1 
ATOM   6111  N N   . GLU B 2 11  ? 175.322 184.804 93.406  1.00 40.29  ? 29   GLU C N   1 
ATOM   6112  C CA  . GLU B 2 11  ? 174.426 185.946 93.446  1.00 40.29  ? 29   GLU C CA  1 
ATOM   6113  C C   . GLU B 2 11  ? 173.628 185.978 94.740  1.00 40.29  ? 29   GLU C C   1 
ATOM   6114  O O   . GLU B 2 11  ? 173.353 184.936 95.332  1.00 40.29  ? 29   GLU C O   1 
ATOM   6115  C CB  . GLU B 2 11  ? 173.484 185.882 92.237  1.00 53.10  ? 29   GLU C CB  1 
ATOM   6116  C CG  . GLU B 2 11  ? 172.425 184.751 92.310  1.00 53.10  ? 29   GLU C CG  1 
ATOM   6117  C CD  . GLU B 2 11  ? 173.006 183.395 91.929  1.00 53.10  ? 29   GLU C CD  1 
ATOM   6118  O OE1 . GLU B 2 11  ? 174.149 183.370 91.524  1.00 53.10  ? 29   GLU C OE1 1 
ATOM   6119  O OE2 . GLU B 2 11  ? 172.345 182.389 92.077  1.00 53.10  ? 29   GLU C OE2 1 
ATOM   6120  N N   . GLY B 2 12  ? 173.196 187.164 95.146  1.00 40.29  ? 30   GLY C N   1 
ATOM   6121  C CA  . GLY B 2 12  ? 172.360 187.276 96.328  1.00 40.29  ? 30   GLY C CA  1 
ATOM   6122  C C   . GLY B 2 12  ? 172.078 188.721 96.705  1.00 40.29  ? 30   GLY C C   1 
ATOM   6123  O O   . GLY B 2 12  ? 172.559 189.650 96.054  1.00 40.29  ? 30   GLY C O   1 
ATOM   6124  N N   . ASP B 2 13  ? 171.288 188.891 97.767  1.00 40.29  ? 31   ASP C N   1 
ATOM   6125  C CA  . ASP B 2 13  ? 170.874 190.181 98.302  1.00 40.29  ? 31   ASP C CA  1 
ATOM   6126  C C   . ASP B 2 13  ? 171.933 190.652 99.277  1.00 40.29  ? 31   ASP C C   1 
ATOM   6127  O O   . ASP B 2 13  ? 172.166 191.848 99.456  1.00 40.29  ? 31   ASP C O   1 
ATOM   6128  C CB  . ASP B 2 13  ? 169.541 190.029 99.027  1.00 51.30  ? 31   ASP C CB  1 
ATOM   6129  C CG  . ASP B 2 13  ? 168.409 189.629 98.120  1.00 51.30  ? 31   ASP C CG  1 
ATOM   6130  O OD1 . ASP B 2 13  ? 168.020 190.416 97.287  1.00 51.30  ? 31   ASP C OD1 1 
ATOM   6131  O OD2 . ASP B 2 13  ? 167.953 188.496 98.243  1.00 51.30  ? 31   ASP C OD2 1 
ATOM   6132  N N   . LEU B 2 14  ? 172.573 189.684 99.913  1.00 40.29  ? 32   LEU C N   1 
ATOM   6133  C CA  . LEU B 2 14  ? 173.632 189.929 100.863 1.00 40.29  ? 32   LEU C CA  1 
ATOM   6134  C C   . LEU B 2 14  ? 174.713 188.981 100.453 1.00 40.29  ? 32   LEU C C   1 
ATOM   6135  O O   . LEU B 2 14  ? 174.417 187.837 100.130 1.00 40.29  ? 32   LEU C O   1 
ATOM   6136  C CB  . LEU B 2 14  ? 173.186 189.669 102.292 1.00 57.27  ? 32   LEU C CB  1 
ATOM   6137  C CG  . LEU B 2 14  ? 174.183 190.023 103.397 1.00 57.27  ? 32   LEU C CG  1 
ATOM   6138  C CD1 . LEU B 2 14  ? 173.378 190.442 104.610 1.00 57.27  ? 32   LEU C CD1 1 
ATOM   6139  C CD2 . LEU B 2 14  ? 175.090 188.822 103.741 1.00 57.27  ? 32   LEU C CD2 1 
ATOM   6140  N N   . VAL B 2 15  ? 175.940 189.445 100.410 1.00 40.29  ? 33   VAL C N   1 
ATOM   6141  C CA  . VAL B 2 15  ? 177.014 188.592 99.970  1.00 40.29  ? 33   VAL C CA  1 
ATOM   6142  C C   . VAL B 2 15  ? 177.981 188.255 101.065 1.00 40.29  ? 33   VAL C C   1 
ATOM   6143  O O   . VAL B 2 15  ? 178.526 189.142 101.716 1.00 40.29  ? 33   VAL C O   1 
ATOM   6144  C CB  . VAL B 2 15  ? 177.737 189.296 98.825  1.00 56.74  ? 33   VAL C CB  1 
ATOM   6145  C CG1 . VAL B 2 15  ? 178.896 188.491 98.343  1.00 56.74  ? 33   VAL C CG1 1 
ATOM   6146  C CG2 . VAL B 2 15  ? 176.725 189.522 97.692  1.00 56.74  ? 33   VAL C CG2 1 
ATOM   6147  N N   . LEU B 2 16  ? 178.197 186.970 101.272 1.00 40.29  ? 34   LEU C N   1 
ATOM   6148  C CA  . LEU B 2 16  ? 179.149 186.555 102.274 1.00 40.29  ? 34   LEU C CA  1 
ATOM   6149  C C   . LEU B 2 16  ? 180.433 186.108 101.653 1.00 40.29  ? 34   LEU C C   1 
ATOM   6150  O O   . LEU B 2 16  ? 180.495 185.172 100.863 1.00 40.29  ? 34   LEU C O   1 
ATOM   6151  C CB  . LEU B 2 16  ? 178.595 185.439 103.149 1.00 57.27  ? 34   LEU C CB  1 
ATOM   6152  C CG  . LEU B 2 16  ? 177.383 185.788 104.026 1.00 57.27  ? 34   LEU C CG  1 
ATOM   6153  C CD1 . LEU B 2 16  ? 176.908 184.530 104.720 1.00 57.27  ? 34   LEU C CD1 1 
ATOM   6154  C CD2 . LEU B 2 16  ? 177.786 186.844 105.083 1.00 57.27  ? 34   LEU C CD2 1 
ATOM   6155  N N   . GLY B 2 17  ? 181.486 186.752 102.042 1.00 40.29  ? 35   GLY C N   1 
ATOM   6156  C CA  . GLY B 2 17  ? 182.749 186.353 101.511 1.00 40.29  ? 35   GLY C CA  1 
ATOM   6157  C C   . GLY B 2 17  ? 183.240 185.208 102.362 1.00 40.29  ? 35   GLY C C   1 
ATOM   6158  O O   . GLY B 2 17  ? 182.598 184.837 103.353 1.00 40.29  ? 35   GLY C O   1 
ATOM   6159  N N   . GLY B 2 18  ? 184.397 184.698 102.033 1.00 40.29  ? 36   GLY C N   1 
ATOM   6160  C CA  . GLY B 2 18  ? 184.960 183.614 102.800 1.00 40.29  ? 36   GLY C CA  1 
ATOM   6161  C C   . GLY B 2 18  ? 186.313 183.229 102.285 1.00 40.29  ? 36   GLY C C   1 
ATOM   6162  O O   . GLY B 2 18  ? 186.763 183.787 101.293 1.00 40.29  ? 36   GLY C O   1 
ATOM   6163  N N   . LEU B 2 19  ? 186.972 182.309 102.967 1.00 40.29  ? 37   LEU C N   1 
ATOM   6164  C CA  . LEU B 2 19  ? 188.322 181.926 102.555 1.00 40.29  ? 37   LEU C CA  1 
ATOM   6165  C C   . LEU B 2 19  ? 188.723 180.498 102.927 1.00 40.29  ? 37   LEU C C   1 
ATOM   6166  O O   . LEU B 2 19  ? 188.820 180.128 104.112 1.00 40.29  ? 37   LEU C O   1 
ATOM   6167  C CB  . LEU B 2 19  ? 189.280 182.930 103.196 1.00 57.27  ? 37   LEU C CB  1 
ATOM   6168  C CG  . LEU B 2 19  ? 190.753 182.789 102.948 1.00 57.27  ? 37   LEU C CG  1 
ATOM   6169  C CD1 . LEU B 2 19  ? 191.069 183.000 101.555 1.00 57.27  ? 37   LEU C CD1 1 
ATOM   6170  C CD2 . LEU B 2 19  ? 191.450 183.801 103.722 1.00 57.27  ? 37   LEU C CD2 1 
ATOM   6171  N N   . PHE B 2 20  ? 189.016 179.713 101.901 1.00 40.29  ? 38   PHE C N   1 
ATOM   6172  C CA  . PHE B 2 20  ? 189.369 178.312 102.046 1.00 40.29  ? 38   PHE C CA  1 
ATOM   6173  C C   . PHE B 2 20  ? 190.696 177.994 101.400 1.00 40.29  ? 38   PHE C C   1 
ATOM   6174  O O   . PHE B 2 20  ? 191.032 178.581 100.376 1.00 40.29  ? 38   PHE C O   1 
ATOM   6175  C CB  . PHE B 2 20  ? 188.277 177.460 101.421 1.00 54.49  ? 38   PHE C CB  1 
ATOM   6176  C CG  . PHE B 2 20  ? 186.991 177.469 102.180 1.00 54.49  ? 38   PHE C CG  1 
ATOM   6177  C CD1 . PHE B 2 20  ? 186.182 178.588 102.265 1.00 54.49  ? 38   PHE C CD1 1 
ATOM   6178  C CD2 . PHE B 2 20  ? 186.555 176.314 102.772 1.00 54.49  ? 38   PHE C CD2 1 
ATOM   6179  C CE1 . PHE B 2 20  ? 185.027 178.559 102.950 1.00 54.49  ? 38   PHE C CE1 1 
ATOM   6180  C CE2 . PHE B 2 20  ? 185.366 176.279 103.450 1.00 54.49  ? 38   PHE C CE2 1 
ATOM   6181  C CZ  . PHE B 2 20  ? 184.613 177.403 103.547 1.00 54.49  ? 38   PHE C CZ  1 
ATOM   6182  N N   . PRO B 2 21  ? 191.452 177.016 101.902 1.00 40.29  ? 39   PRO C N   1 
ATOM   6183  C CA  . PRO B 2 21  ? 192.701 176.541 101.350 1.00 40.29  ? 39   PRO C CA  1 
ATOM   6184  C C   . PRO B 2 21  ? 192.472 175.625 100.176 1.00 40.29  ? 39   PRO C C   1 
ATOM   6185  O O   . PRO B 2 21  ? 192.777 174.440 100.221 1.00 40.29  ? 39   PRO C O   1 
ATOM   6186  C CB  . PRO B 2 21  ? 193.323 175.798 102.521 1.00 68.85  ? 39   PRO C CB  1 
ATOM   6187  C CG  . PRO B 2 21  ? 192.149 175.255 103.251 1.00 68.85  ? 39   PRO C CG  1 
ATOM   6188  C CD  . PRO B 2 21  ? 191.068 176.330 103.133 1.00 68.85  ? 39   PRO C CD  1 
ATOM   6189  N N   . VAL B 2 22  ? 191.945 176.167 99.097  1.00 40.29  ? 40   VAL C N   1 
ATOM   6190  C CA  . VAL B 2 22  ? 191.698 175.310 97.955  1.00 40.29  ? 40   VAL C CA  1 
ATOM   6191  C C   . VAL B 2 22  ? 192.999 174.710 97.534  1.00 40.29  ? 40   VAL C C   1 
ATOM   6192  O O   . VAL B 2 22  ? 193.083 173.500 97.328  1.00 40.29  ? 40   VAL C O   1 
ATOM   6193  C CB  . VAL B 2 22  ? 191.166 176.088 96.759  1.00 56.74  ? 40   VAL C CB  1 
ATOM   6194  C CG1 . VAL B 2 22  ? 191.122 175.207 95.522  1.00 56.74  ? 40   VAL C CG1 1 
ATOM   6195  C CG2 . VAL B 2 22  ? 189.856 176.584 97.072  1.00 56.74  ? 40   VAL C CG2 1 
ATOM   6196  N N   . HIS B 2 23  ? 194.026 175.536 97.451  1.00 40.29  ? 41   HIS C N   1 
ATOM   6197  C CA  . HIS B 2 23  ? 195.317 174.998 97.101  1.00 40.29  ? 41   HIS C CA  1 
ATOM   6198  C C   . HIS B 2 23  ? 196.259 174.930 98.266  1.00 40.29  ? 41   HIS C C   1 
ATOM   6199  O O   . HIS B 2 23  ? 196.149 175.676 99.246  1.00 40.29  ? 41   HIS C O   1 
ATOM   6200  C CB  . HIS B 2 23  ? 195.990 175.758 95.981  1.00 53.51  ? 41   HIS C CB  1 
ATOM   6201  C CG  . HIS B 2 23  ? 195.288 175.683 94.690  1.00 53.51  ? 41   HIS C CG  1 
ATOM   6202  N ND1 . HIS B 2 23  ? 194.376 176.616 94.305  1.00 53.51  ? 41   HIS C ND1 1 
ATOM   6203  C CD2 . HIS B 2 23  ? 195.352 174.786 93.685  1.00 53.51  ? 41   HIS C CD2 1 
ATOM   6204  C CE1 . HIS B 2 23  ? 193.911 176.318 93.125  1.00 53.51  ? 41   HIS C CE1 1 
ATOM   6205  N NE2 . HIS B 2 23  ? 194.479 175.207 92.713  1.00 53.51  ? 41   HIS C NE2 1 
ATOM   6206  N N   . GLN B 2 24  ? 197.200 174.028 98.103  1.00 40.29  ? 42   GLN C N   1 
ATOM   6207  C CA  . GLN B 2 24  ? 198.310 173.801 98.981  1.00 40.29  ? 42   GLN C CA  1 
ATOM   6208  C C   . GLN B 2 24  ? 199.302 174.899 98.708  1.00 40.29  ? 42   GLN C C   1 
ATOM   6209  O O   . GLN B 2 24  ? 199.093 175.716 97.815  1.00 40.29  ? 42   GLN C O   1 
ATOM   6210  C CB  . GLN B 2 24  ? 198.929 172.450 98.639  1.00 54.76  ? 42   GLN C CB  1 
ATOM   6211  C CG  . GLN B 2 24  ? 198.030 171.279 98.899  1.00 54.76  ? 42   GLN C CG  1 
ATOM   6212  C CD  . GLN B 2 24  ? 198.593 169.974 98.424  1.00 54.76  ? 42   GLN C CD  1 
ATOM   6213  O OE1 . GLN B 2 24  ? 199.796 169.751 98.609  1.00 54.76  ? 42   GLN C OE1 1 
ATOM   6214  N NE2 . GLN B 2 24  ? 197.784 169.102 97.814  1.00 54.76  ? 42   GLN C NE2 1 
ATOM   6215  N N   . LYS B 2 25  ? 200.374 174.969 99.464  1.00 40.29  ? 43   LYS C N   1 
ATOM   6216  C CA  . LYS B 2 25  ? 201.358 175.988 99.140  1.00 40.29  ? 43   LYS C CA  1 
ATOM   6217  C C   . LYS B 2 25  ? 202.158 175.553 97.923  1.00 40.29  ? 43   LYS C C   1 
ATOM   6218  O O   . LYS B 2 25  ? 202.515 174.381 97.806  1.00 40.29  ? 43   LYS C O   1 
ATOM   6219  C CB  . LYS B 2 25  ? 202.344 176.212 100.285 1.00 55.94  ? 43   LYS C CB  1 
ATOM   6220  C CG  . LYS B 2 25  ? 201.793 176.828 101.519 1.00 55.94  ? 43   LYS C CG  1 
ATOM   6221  C CD  . LYS B 2 25  ? 202.906 177.035 102.535 1.00 55.94  ? 43   LYS C CD  1 
ATOM   6222  C CE  . LYS B 2 25  ? 202.420 177.767 103.769 1.00 55.94  ? 43   LYS C CE  1 
ATOM   6223  N NZ  . LYS B 2 25  ? 203.492 177.895 104.788 1.00 55.94  ? 43   LYS C NZ  1 
ATOM   6224  N N   . GLY B 2 26  ? 202.518 176.499 97.060  1.00 35.72  ? 44   GLY C N   1 
ATOM   6225  C CA  . GLY B 2 26  ? 203.413 176.226 95.930  1.00 35.72  ? 44   GLY C CA  1 
ATOM   6226  C C   . GLY B 2 26  ? 204.850 176.568 96.333  1.00 35.72  ? 44   GLY C C   1 
ATOM   6227  O O   . GLY B 2 26  ? 205.801 176.523 95.530  1.00 35.72  ? 44   GLY C O   1 
ATOM   6228  N N   . GLY B 2 27  ? 204.985 176.928 97.605  1.00 46.56  ? 45   GLY C N   1 
ATOM   6229  C CA  . GLY B 2 27  ? 206.230 177.323 98.215  1.00 46.56  ? 45   GLY C CA  1 
ATOM   6230  C C   . GLY B 2 27  ? 206.807 178.500 97.442  1.00 46.56  ? 45   GLY C C   1 
ATOM   6231  O O   . GLY B 2 27  ? 206.136 179.536 97.307  1.00 46.56  ? 45   GLY C O   1 
ATOM   6232  N N   . PRO B 2 28  ? 208.108 178.455 97.093  1.00 50.02  ? 46   PRO C N   1 
ATOM   6233  C CA  . PRO B 2 28  ? 208.818 179.441 96.310  1.00 50.02  ? 46   PRO C CA  1 
ATOM   6234  C C   . PRO B 2 28  ? 208.754 179.184 94.805  1.00 50.02  ? 46   PRO C C   1 
ATOM   6235  O O   . PRO B 2 28  ? 209.400 179.900 94.042  1.00 50.02  ? 46   PRO C O   1 
ATOM   6236  C CB  . PRO B 2 28  ? 210.247 179.271 96.823  1.00 85.47  ? 46   PRO C CB  1 
ATOM   6237  C CG  . PRO B 2 28  ? 210.361 177.784 97.082  1.00 85.47  ? 46   PRO C CG  1 
ATOM   6238  C CD  . PRO B 2 28  ? 208.986 177.360 97.587  1.00 85.47  ? 46   PRO C CD  1 
ATOM   6239  N N   . ALA B 2 29  ? 208.089 178.102 94.377  1.00 55.03  ? 47   ALA C N   1 
ATOM   6240  C CA  . ALA B 2 29  ? 208.127 177.743 92.964  1.00 55.03  ? 47   ALA C CA  1 
ATOM   6241  C C   . ALA B 2 29  ? 206.976 178.391 92.226  1.00 55.03  ? 47   ALA C C   1 
ATOM   6242  O O   . ALA B 2 29  ? 207.144 178.971 91.153  1.00 55.03  ? 47   ALA C O   1 
ATOM   6243  C CB  . ALA B 2 29  ? 208.062 176.237 92.810  1.00 74.34  ? 47   ALA C CB  1 
ATOM   6244  N N   . GLU B 2 30  ? 205.815 178.289 92.842  1.00 48.24  ? 48   GLU C N   1 
ATOM   6245  C CA  . GLU B 2 30  ? 204.553 178.809 92.358  1.00 48.24  ? 48   GLU C CA  1 
ATOM   6246  C C   . GLU B 2 30  ? 203.875 179.347 93.567  1.00 48.24  ? 48   GLU C C   1 
ATOM   6247  O O   . GLU B 2 30  ? 204.156 178.904 94.668  1.00 48.24  ? 48   GLU C O   1 
ATOM   6248  C CB  . GLU B 2 30  ? 203.683 177.721 91.726  1.00 63.58  ? 48   GLU C CB  1 
ATOM   6249  C CG  . GLU B 2 30  ? 204.150 177.175 90.379  1.00 63.58  ? 48   GLU C CG  1 
ATOM   6250  C CD  . GLU B 2 30  ? 203.943 178.156 89.236  1.00 63.58  ? 48   GLU C CD  1 
ATOM   6251  O OE1 . GLU B 2 30  ? 203.274 179.152 89.435  1.00 63.58  ? 48   GLU C OE1 1 
ATOM   6252  O OE2 . GLU B 2 30  ? 204.429 177.894 88.158  1.00 63.58  ? 48   GLU C OE2 1 
ATOM   6253  N N   . ASP B 2 31  ? 202.950 180.259 93.446  1.00 44.33  ? 49   ASP C N   1 
ATOM   6254  C CA  . ASP B 2 31  ? 202.342 180.585 94.725  1.00 44.33  ? 49   ASP C CA  1 
ATOM   6255  C C   . ASP B 2 31  ? 201.530 179.422 95.304  1.00 44.33  ? 49   ASP C C   1 
ATOM   6256  O O   . ASP B 2 31  ? 201.600 179.172 96.516  1.00 44.33  ? 49   ASP C O   1 
ATOM   6257  C CB  . ASP B 2 31  ? 201.392 181.768 94.612  1.00 56.45  ? 49   ASP C CB  1 
ATOM   6258  C CG  . ASP B 2 31  ? 202.037 183.079 94.405  1.00 56.45  ? 49   ASP C CG  1 
ATOM   6259  O OD1 . ASP B 2 31  ? 203.228 183.221 94.573  1.00 56.45  ? 49   ASP C OD1 1 
ATOM   6260  O OD2 . ASP B 2 31  ? 201.296 183.981 94.108  1.00 56.45  ? 49   ASP C OD2 1 
ATOM   6261  N N   . CYS B 2 32  ? 200.793 178.678 94.437  1.00 35.64  ? 50   CYS C N   1 
ATOM   6262  C CA  . CYS B 2 32  ? 199.857 177.630 94.816  1.00 35.64  ? 50   CYS C CA  1 
ATOM   6263  C C   . CYS B 2 32  ? 200.359 176.261 94.391  1.00 35.64  ? 50   CYS C C   1 
ATOM   6264  O O   . CYS B 2 32  ? 200.912 176.087 93.297  1.00 35.64  ? 50   CYS C O   1 
ATOM   6265  C CB  . CYS B 2 32  ? 198.465 177.896 94.203  1.00 46.18  ? 50   CYS C CB  1 
ATOM   6266  S SG  . CYS B 2 32  ? 197.682 179.501 94.687  1.00 46.18  ? 50   CYS C SG  1 
ATOM   6267  N N   . GLY B 2 33  ? 200.143 175.309 95.265  1.00 40.29  ? 51   GLY C N   1 
ATOM   6268  C CA  . GLY B 2 33  ? 200.462 173.922 95.072  1.00 40.29  ? 51   GLY C CA  1 
ATOM   6269  C C   . GLY B 2 33  ? 199.210 173.279 94.536  1.00 40.29  ? 51   GLY C C   1 
ATOM   6270  O O   . GLY B 2 33  ? 198.345 173.994 94.036  1.00 40.29  ? 51   GLY C O   1 
ATOM   6271  N N   . PRO B 2 34  ? 199.116 171.950 94.566  1.00 40.29  ? 52   PRO C N   1 
ATOM   6272  C CA  . PRO B 2 34  ? 198.005 171.142 94.112  1.00 40.29  ? 52   PRO C CA  1 
ATOM   6273  C C   . PRO B 2 34  ? 196.837 171.420 95.016  1.00 40.29  ? 52   PRO C C   1 
ATOM   6274  O O   . PRO B 2 34  ? 197.025 171.999 96.085  1.00 40.29  ? 52   PRO C O   1 
ATOM   6275  C CB  . PRO B 2 34  ? 198.510 169.708 94.274  1.00 68.85  ? 52   PRO C CB  1 
ATOM   6276  C CG  . PRO B 2 34  ? 200.019 169.827 94.373  1.00 68.85  ? 52   PRO C CG  1 
ATOM   6277  C CD  . PRO B 2 34  ? 200.265 171.153 95.043  1.00 68.85  ? 52   PRO C CD  1 
ATOM   6278  N N   . VAL B 2 35  ? 195.655 171.051 94.591  1.00 40.29  ? 53   VAL C N   1 
ATOM   6279  C CA  . VAL B 2 35  ? 194.488 171.240 95.439  1.00 40.29  ? 53   VAL C CA  1 
ATOM   6280  C C   . VAL B 2 35  ? 194.509 170.345 96.670  1.00 40.29  ? 53   VAL C C   1 
ATOM   6281  O O   . VAL B 2 35  ? 195.075 169.255 96.658  1.00 40.29  ? 53   VAL C O   1 
ATOM   6282  C CB  . VAL B 2 35  ? 193.164 170.993 94.683  1.00 56.74  ? 53   VAL C CB  1 
ATOM   6283  C CG1 . VAL B 2 35  ? 193.028 171.984 93.537  1.00 56.74  ? 53   VAL C CG1 1 
ATOM   6284  C CG2 . VAL B 2 35  ? 193.093 169.531 94.179  1.00 56.74  ? 53   VAL C CG2 1 
ATOM   6285  N N   . ASN B 2 36  ? 193.880 170.820 97.732  1.00 40.29  ? 54   ASN C N   1 
ATOM   6286  C CA  . ASN B 2 36  ? 193.672 170.058 98.950  1.00 40.29  ? 54   ASN C CA  1 
ATOM   6287  C C   . ASN B 2 36  ? 192.334 169.360 98.902  1.00 40.29  ? 54   ASN C C   1 
ATOM   6288  O O   . ASN B 2 36  ? 191.289 169.987 99.121  1.00 40.29  ? 54   ASN C O   1 
ATOM   6289  C CB  . ASN B 2 36  ? 193.662 170.932 100.169 1.00 52.18  ? 54   ASN C CB  1 
ATOM   6290  C CG  . ASN B 2 36  ? 194.930 171.454 100.589 1.00 52.18  ? 54   ASN C CG  1 
ATOM   6291  O OD1 . ASN B 2 36  ? 195.834 170.656 100.844 1.00 52.18  ? 54   ASN C OD1 1 
ATOM   6292  N ND2 . ASN B 2 36  ? 195.049 172.743 100.704 1.00 52.18  ? 54   ASN C ND2 1 
ATOM   6293  N N   . GLU B 2 37  ? 192.313 168.060 98.681  1.00 40.29  ? 55   GLU C N   1 
ATOM   6294  C CA  . GLU B 2 37  ? 191.009 167.445 98.526  1.00 40.29  ? 55   GLU C CA  1 
ATOM   6295  C C   . GLU B 2 37  ? 190.200 167.497 99.803  1.00 40.29  ? 55   GLU C C   1 
ATOM   6296  O O   . GLU B 2 37  ? 189.038 167.904 99.800  1.00 40.29  ? 55   GLU C O   1 
ATOM   6297  C CB  . GLU B 2 37  ? 191.166 165.973 98.145  1.00 54.07  ? 55   GLU C CB  1 
ATOM   6298  C CG  . GLU B 2 37  ? 191.802 165.738 96.798  1.00 54.07  ? 55   GLU C CG  1 
ATOM   6299  C CD  . GLU B 2 37  ? 193.289 165.848 96.859  1.00 54.07  ? 55   GLU C CD  1 
ATOM   6300  O OE1 . GLU B 2 37  ? 193.808 166.016 97.952  1.00 54.07  ? 55   GLU C OE1 1 
ATOM   6301  O OE2 . GLU B 2 37  ? 193.910 165.786 95.835  1.00 54.07  ? 55   GLU C OE2 1 
ATOM   6302  N N   . HIS B 2 38  ? 190.838 167.205 100.923 1.00 40.29  ? 56   HIS C N   1 
ATOM   6303  C CA  . HIS B 2 38  ? 190.079 167.158 102.155 1.00 40.29  ? 56   HIS C CA  1 
ATOM   6304  C C   . HIS B 2 38  ? 190.042 168.482 102.890 1.00 40.29  ? 56   HIS C C   1 
ATOM   6305  O O   . HIS B 2 38  ? 189.091 168.768 103.613 1.00 40.29  ? 56   HIS C O   1 
ATOM   6306  C CB  . HIS B 2 38  ? 190.669 166.092 103.071 1.00 51.84  ? 56   HIS C CB  1 
ATOM   6307  C CG  . HIS B 2 38  ? 190.537 164.697 102.534 1.00 51.84  ? 56   HIS C CG  1 
ATOM   6308  N ND1 . HIS B 2 38  ? 189.326 164.050 102.438 1.00 51.84  ? 56   HIS C ND1 1 
ATOM   6309  C CD2 . HIS B 2 38  ? 191.461 163.834 102.049 1.00 51.84  ? 56   HIS C CD2 1 
ATOM   6310  C CE1 . HIS B 2 38  ? 189.508 162.849 101.927 1.00 51.84  ? 56   HIS C CE1 1 
ATOM   6311  N NE2 . HIS B 2 38  ? 190.796 162.689 101.680 1.00 51.84  ? 56   HIS C NE2 1 
ATOM   6312  N N   . ARG B 2 39  ? 191.071 169.300 102.715 1.00 40.29  ? 57   ARG C N   1 
ATOM   6313  C CA  . ARG B 2 39  ? 191.128 170.543 103.463 1.00 40.29  ? 57   ARG C CA  1 
ATOM   6314  C C   . ARG B 2 39  ? 190.501 171.711 102.738 1.00 40.29  ? 57   ARG C C   1 
ATOM   6315  O O   . ARG B 2 39  ? 190.073 172.683 103.367 1.00 40.29  ? 57   ARG C O   1 
ATOM   6316  C CB  . ARG B 2 39  ? 192.558 170.891 103.830 1.00 58.90  ? 57   ARG C CB  1 
ATOM   6317  C CG  . ARG B 2 39  ? 193.201 170.000 104.862 1.00 58.90  ? 57   ARG C CG  1 
ATOM   6318  C CD  . ARG B 2 39  ? 194.515 170.545 105.275 1.00 58.90  ? 57   ARG C CD  1 
ATOM   6319  N NE  . ARG B 2 39  ? 195.473 170.461 104.171 1.00 58.90  ? 57   ARG C NE  1 
ATOM   6320  C CZ  . ARG B 2 39  ? 196.295 169.410 103.921 1.00 58.90  ? 57   ARG C CZ  1 
ATOM   6321  N NH1 . ARG B 2 39  ? 197.077 169.435 102.860 1.00 58.90  ? 57   ARG C NH1 1 
ATOM   6322  N NH2 . ARG B 2 39  ? 196.320 168.361 104.720 1.00 58.90  ? 57   ARG C NH2 1 
ATOM   6323  N N   . GLY B 2 40  ? 190.493 171.639 101.414 1.00 40.29  ? 58   GLY C N   1 
ATOM   6324  C CA  . GLY B 2 40  ? 190.039 172.690 100.539 1.00 40.29  ? 58   GLY C CA  1 
ATOM   6325  C C   . GLY B 2 40  ? 188.681 172.389 99.948  1.00 40.29  ? 58   GLY C C   1 
ATOM   6326  O O   . GLY B 2 40  ? 187.670 172.985 100.335 1.00 40.29  ? 58   GLY C O   1 
ATOM   6327  N N   . ILE B 2 41  ? 188.686 171.526 98.940  1.00 40.29  ? 59   ILE C N   1 
ATOM   6328  C CA  . ILE B 2 41  ? 187.497 171.252 98.153  1.00 40.29  ? 59   ILE C CA  1 
ATOM   6329  C C   . ILE B 2 41  ? 186.370 170.580 98.882  1.00 40.29  ? 59   ILE C C   1 
ATOM   6330  O O   . ILE B 2 41  ? 185.231 170.993 98.713  1.00 40.29  ? 59   ILE C O   1 
ATOM   6331  C CB  . ILE B 2 41  ? 187.848 170.508 96.867  1.00 57.27  ? 59   ILE C CB  1 
ATOM   6332  C CG1 . ILE B 2 41  ? 188.643 171.513 95.978  1.00 57.27  ? 59   ILE C CG1 1 
ATOM   6333  C CG2 . ILE B 2 41  ? 186.564 169.953 96.160  1.00 57.27  ? 59   ILE C CG2 1 
ATOM   6334  C CD1 . ILE B 2 41  ? 189.308 170.936 94.772  1.00 57.27  ? 59   ILE C CD1 1 
ATOM   6335  N N   . GLN B 2 42  ? 186.617 169.552 99.668  1.00 40.29  ? 60   GLN C N   1 
ATOM   6336  C CA  . GLN B 2 42  ? 185.481 168.961 100.350 1.00 40.29  ? 60   GLN C CA  1 
ATOM   6337  C C   . GLN B 2 42  ? 184.856 169.960 101.308 1.00 40.29  ? 60   GLN C C   1 
ATOM   6338  O O   . GLN B 2 42  ? 183.634 169.978 101.484 1.00 40.29  ? 60   GLN C O   1 
ATOM   6339  C CB  . GLN B 2 42  ? 185.883 167.685 101.071 1.00 54.76  ? 60   GLN C CB  1 
ATOM   6340  C CG  . GLN B 2 42  ? 186.185 166.550 100.122 1.00 54.76  ? 60   GLN C CG  1 
ATOM   6341  C CD  . GLN B 2 42  ? 186.720 165.322 100.813 1.00 54.76  ? 60   GLN C CD  1 
ATOM   6342  O OE1 . GLN B 2 42  ? 186.950 165.296 102.042 1.00 54.76  ? 60   GLN C OE1 1 
ATOM   6343  N NE2 . GLN B 2 42  ? 186.917 164.273 100.026 1.00 54.76  ? 60   GLN C NE2 1 
ATOM   6344  N N   . ARG B 2 43  ? 185.672 170.805 101.927 1.00 40.29  ? 61   ARG C N   1 
ATOM   6345  C CA  . ARG B 2 43  ? 185.106 171.757 102.846 1.00 40.29  ? 61   ARG C CA  1 
ATOM   6346  C C   . ARG B 2 43  ? 184.339 172.815 102.068 1.00 40.29  ? 61   ARG C C   1 
ATOM   6347  O O   . ARG B 2 43  ? 183.230 173.182 102.449 1.00 40.29  ? 61   ARG C O   1 
ATOM   6348  C CB  . ARG B 2 43  ? 186.186 172.338 103.720 1.00 56.58  ? 61   ARG C CB  1 
ATOM   6349  C CG  . ARG B 2 43  ? 186.771 171.300 104.688 1.00 56.58  ? 61   ARG C CG  1 
ATOM   6350  C CD  . ARG B 2 43  ? 187.786 171.867 105.546 1.00 56.58  ? 61   ARG C CD  1 
ATOM   6351  N NE  . ARG B 2 43  ? 188.506 170.863 106.354 1.00 56.58  ? 61   ARG C NE  1 
ATOM   6352  C CZ  . ARG B 2 43  ? 189.754 171.043 106.861 1.00 56.58  ? 61   ARG C CZ  1 
ATOM   6353  N NH1 . ARG B 2 43  ? 190.326 170.109 107.615 1.00 56.58  ? 61   ARG C NH1 1 
ATOM   6354  N NH2 . ARG B 2 43  ? 190.423 172.145 106.572 1.00 56.58  ? 61   ARG C NH2 1 
ATOM   6355  N N   . LEU B 2 44  ? 184.858 173.256 100.934 1.00 40.29  ? 62   LEU C N   1 
ATOM   6356  C CA  . LEU B 2 44  ? 184.083 174.205 100.166 1.00 40.29  ? 62   LEU C CA  1 
ATOM   6357  C C   . LEU B 2 44  ? 182.823 173.629 99.641  1.00 40.29  ? 62   LEU C C   1 
ATOM   6358  O O   . LEU B 2 44  ? 181.811 174.317 99.555  1.00 40.29  ? 62   LEU C O   1 
ATOM   6359  C CB  . LEU B 2 44  ? 184.808 174.693 98.930  1.00 57.27  ? 62   LEU C CB  1 
ATOM   6360  C CG  . LEU B 2 44  ? 185.886 175.650 99.090  1.00 57.27  ? 62   LEU C CG  1 
ATOM   6361  C CD1 . LEU B 2 44  ? 186.594 175.788 97.822  1.00 57.27  ? 62   LEU C CD1 1 
ATOM   6362  C CD2 . LEU B 2 44  ? 185.286 176.962 99.402  1.00 57.27  ? 62   LEU C CD2 1 
ATOM   6363  N N   . GLU B 2 45  ? 182.859 172.387 99.222  1.00 40.29  ? 63   GLU C N   1 
ATOM   6364  C CA  . GLU B 2 45  ? 181.660 171.893 98.637  1.00 40.29  ? 63   GLU C CA  1 
ATOM   6365  C C   . GLU B 2 45  ? 180.631 171.780 99.741  1.00 40.29  ? 63   GLU C C   1 
ATOM   6366  O O   . GLU B 2 45  ? 179.470 172.107 99.529  1.00 40.29  ? 63   GLU C O   1 
ATOM   6367  C CB  . GLU B 2 45  ? 181.890 170.578 97.931  1.00 51.51  ? 63   GLU C CB  1 
ATOM   6368  C CG  . GLU B 2 45  ? 180.769 170.220 97.008  1.00 51.51  ? 63   GLU C CG  1 
ATOM   6369  C CD  . GLU B 2 45  ? 180.669 171.184 95.808  1.00 51.51  ? 63   GLU C CD  1 
ATOM   6370  O OE1 . GLU B 2 45  ? 181.657 171.845 95.511  1.00 51.51  ? 63   GLU C OE1 1 
ATOM   6371  O OE2 . GLU B 2 45  ? 179.613 171.298 95.230  1.00 51.51  ? 63   GLU C OE2 1 
ATOM   6372  N N   . ALA B 2 46  ? 181.048 171.369 100.943 1.00 40.29  ? 64   ALA C N   1 
ATOM   6373  C CA  . ALA B 2 46  ? 180.110 171.282 102.039 1.00 40.29  ? 64   ALA C CA  1 
ATOM   6374  C C   . ALA B 2 46  ? 179.533 172.644 102.342 1.00 40.29  ? 64   ALA C C   1 
ATOM   6375  O O   . ALA B 2 46  ? 178.338 172.772 102.623 1.00 40.29  ? 64   ALA C O   1 
ATOM   6376  C CB  . ALA B 2 46  ? 180.792 170.746 103.253 1.00 54.43  ? 64   ALA C CB  1 
ATOM   6377  N N   . MET B 2 47  ? 180.377 173.661 102.256 1.00 40.29  ? 65   MET C N   1 
ATOM   6378  C CA  . MET B 2 47  ? 179.948 175.013 102.452 1.00 40.29  ? 65   MET C CA  1 
ATOM   6379  C C   . MET B 2 47  ? 178.869 175.322 101.464 1.00 40.29  ? 65   MET C C   1 
ATOM   6380  O O   . MET B 2 47  ? 177.813 175.804 101.847 1.00 40.29  ? 65   MET C O   1 
ATOM   6381  C CB  . MET B 2 47  ? 181.097 175.969 102.229 1.00 56.05  ? 65   MET C CB  1 
ATOM   6382  C CG  . MET B 2 47  ? 180.735 177.418 102.260 1.00 56.05  ? 65   MET C CG  1 
ATOM   6383  S SD  . MET B 2 47  ? 181.998 178.424 101.528 1.00 56.05  ? 65   MET C SD  1 
ATOM   6384  C CE  . MET B 2 47  ? 181.866 177.944 99.791  1.00 56.05  ? 65   MET C CE  1 
ATOM   6385  N N   . LEU B 2 48  ? 179.127 175.043 100.193 1.00 40.29  ? 66   LEU C N   1 
ATOM   6386  C CA  . LEU B 2 48  ? 178.162 175.337 99.166  1.00 40.29  ? 66   LEU C CA  1 
ATOM   6387  C C   . LEU B 2 48  ? 176.899 174.548 99.347  1.00 40.29  ? 66   LEU C C   1 
ATOM   6388  O O   . LEU B 2 48  ? 175.812 175.100 99.200  1.00 40.29  ? 66   LEU C O   1 
ATOM   6389  C CB  . LEU B 2 48  ? 178.724 175.004 97.782  1.00 57.27  ? 66   LEU C CB  1 
ATOM   6390  C CG  . LEU B 2 48  ? 179.852 175.897 97.234  1.00 57.27  ? 66   LEU C CG  1 
ATOM   6391  C CD1 . LEU B 2 48  ? 180.425 175.259 95.966  1.00 57.27  ? 66   LEU C CD1 1 
ATOM   6392  C CD2 . LEU B 2 48  ? 179.298 177.288 96.903  1.00 57.27  ? 66   LEU C CD2 1 
ATOM   6393  N N   . PHE B 2 49  ? 177.004 173.287 99.758  1.00 40.29  ? 67   PHE C N   1 
ATOM   6394  C CA  . PHE B 2 49  ? 175.808 172.496 99.928  1.00 40.29  ? 67   PHE C CA  1 
ATOM   6395  C C   . PHE B 2 49  ? 174.960 173.178 100.973 1.00 40.29  ? 67   PHE C C   1 
ATOM   6396  O O   . PHE B 2 49  ? 173.755 173.372 100.785 1.00 40.29  ? 67   PHE C O   1 
ATOM   6397  C CB  . PHE B 2 49  ? 176.147 171.090 100.453 1.00 54.49  ? 67   PHE C CB  1 
ATOM   6398  C CG  . PHE B 2 49  ? 176.831 170.085 99.518  1.00 54.49  ? 67   PHE C CG  1 
ATOM   6399  C CD1 . PHE B 2 49  ? 176.691 170.102 98.143  1.00 54.49  ? 67   PHE C CD1 1 
ATOM   6400  C CD2 . PHE B 2 49  ? 177.633 169.086 100.071 1.00 54.49  ? 67   PHE C CD2 1 
ATOM   6401  C CE1 . PHE B 2 49  ? 177.333 169.150 97.364  1.00 54.49  ? 67   PHE C CE1 1 
ATOM   6402  C CE2 . PHE B 2 49  ? 178.269 168.153 99.303  1.00 54.49  ? 67   PHE C CE2 1 
ATOM   6403  C CZ  . PHE B 2 49  ? 178.120 168.179 97.945  1.00 54.49  ? 67   PHE C CZ  1 
ATOM   6404  N N   . ALA B 2 50  ? 175.594 173.597 102.057 1.00 40.29  ? 68   ALA C N   1 
ATOM   6405  C CA  . ALA B 2 50  ? 174.883 174.278 103.101 1.00 40.29  ? 68   ALA C CA  1 
ATOM   6406  C C   . ALA B 2 50  ? 174.362 175.632 102.643 1.00 40.29  ? 68   ALA C C   1 
ATOM   6407  O O   . ALA B 2 50  ? 173.227 175.974 102.952 1.00 40.29  ? 68   ALA C O   1 
ATOM   6408  C CB  . ALA B 2 50  ? 175.783 174.412 104.282 1.00 54.43  ? 68   ALA C CB  1 
ATOM   6409  N N   . LEU B 2 51  ? 175.121 176.375 101.847 1.00 40.29  ? 69   LEU C N   1 
ATOM   6410  C CA  . LEU B 2 51  ? 174.644 177.675 101.407 1.00 40.29  ? 69   LEU C CA  1 
ATOM   6411  C C   . LEU B 2 51  ? 173.427 177.545 100.517 1.00 40.29  ? 69   LEU C C   1 
ATOM   6412  O O   . LEU B 2 51  ? 172.497 178.355 100.613 1.00 40.29  ? 69   LEU C O   1 
ATOM   6413  C CB  . LEU B 2 51  ? 175.744 178.440 100.670 1.00 57.27  ? 69   LEU C CB  1 
ATOM   6414  C CG  . LEU B 2 51  ? 176.949 178.941 101.525 1.00 57.27  ? 69   LEU C CG  1 
ATOM   6415  C CD1 . LEU B 2 51  ? 178.028 179.468 100.579 1.00 57.27  ? 69   LEU C CD1 1 
ATOM   6416  C CD2 . LEU B 2 51  ? 176.502 180.047 102.504 1.00 57.27  ? 69   LEU C CD2 1 
ATOM   6417  N N   . ASP B 2 52  ? 173.395 176.515 99.680  1.00 40.29  ? 70   ASP C N   1 
ATOM   6418  C CA  . ASP B 2 52  ? 172.245 176.320 98.821  1.00 40.29  ? 70   ASP C CA  1 
ATOM   6419  C C   . ASP B 2 52  ? 171.059 175.914 99.669  1.00 40.29  ? 70   ASP C C   1 
ATOM   6420  O O   . ASP B 2 52  ? 169.942 176.377 99.428  1.00 40.29  ? 70   ASP C O   1 
ATOM   6421  C CB  . ASP B 2 52  ? 172.530 175.259 97.760  1.00 51.30  ? 70   ASP C CB  1 
ATOM   6422  C CG  . ASP B 2 52  ? 173.498 175.738 96.652  1.00 51.30  ? 70   ASP C CG  1 
ATOM   6423  O OD1 . ASP B 2 52  ? 173.687 176.920 96.506  1.00 51.30  ? 70   ASP C OD1 1 
ATOM   6424  O OD2 . ASP B 2 52  ? 174.031 174.915 95.938  1.00 51.30  ? 70   ASP C OD2 1 
ATOM   6425  N N   . ARG B 2 53  ? 171.302 175.097 100.699 1.00 40.29  ? 71   ARG C N   1 
ATOM   6426  C CA  . ARG B 2 53  ? 170.239 174.683 101.595 1.00 40.29  ? 71   ARG C CA  1 
ATOM   6427  C C   . ARG B 2 53  ? 169.701 175.886 102.353 1.00 40.29  ? 71   ARG C C   1 
ATOM   6428  O O   . ARG B 2 53  ? 168.504 175.955 102.615 1.00 40.29  ? 71   ARG C O   1 
ATOM   6429  C CB  . ARG B 2 53  ? 170.725 173.635 102.590 1.00 56.58  ? 71   ARG C CB  1 
ATOM   6430  C CG  . ARG B 2 53  ? 171.059 172.230 102.026 1.00 56.58  ? 71   ARG C CG  1 
ATOM   6431  C CD  . ARG B 2 53  ? 169.865 171.445 101.633 1.00 56.58  ? 71   ARG C CD  1 
ATOM   6432  N NE  . ARG B 2 53  ? 168.971 171.208 102.766 1.00 56.58  ? 71   ARG C NE  1 
ATOM   6433  C CZ  . ARG B 2 53  ? 167.749 170.648 102.687 1.00 56.58  ? 71   ARG C CZ  1 
ATOM   6434  N NH1 . ARG B 2 53  ? 167.013 170.514 103.781 1.00 56.58  ? 71   ARG C NH1 1 
ATOM   6435  N NH2 . ARG B 2 53  ? 167.284 170.233 101.530 1.00 56.58  ? 71   ARG C NH2 1 
ATOM   6436  N N   . ILE B 2 54  ? 170.580 176.826 102.714 1.00 40.29  ? 72   ILE C N   1 
ATOM   6437  C CA  . ILE B 2 54  ? 170.166 178.035 103.408 1.00 40.29  ? 72   ILE C CA  1 
ATOM   6438  C C   . ILE B 2 54  ? 169.319 178.879 102.489 1.00 40.29  ? 72   ILE C C   1 
ATOM   6439  O O   . ILE B 2 54  ? 168.238 179.295 102.873 1.00 40.29  ? 72   ILE C O   1 
ATOM   6440  C CB  . ILE B 2 54  ? 171.354 178.866 103.934 1.00 57.27  ? 72   ILE C CB  1 
ATOM   6441  C CG1 . ILE B 2 54  ? 172.048 178.086 105.063 1.00 57.27  ? 72   ILE C CG1 1 
ATOM   6442  C CG2 . ILE B 2 54  ? 170.828 180.251 104.452 1.00 57.27  ? 72   ILE C CG2 1 
ATOM   6443  C CD1 . ILE B 2 54  ? 173.422 178.583 105.476 1.00 57.27  ? 72   ILE C CD1 1 
ATOM   6444  N N   . ASN B 2 55  ? 169.738 179.065 101.247 1.00 40.29  ? 73   ASN C N   1 
ATOM   6445  C CA  . ASN B 2 55  ? 168.944 179.875 100.339 1.00 40.29  ? 73   ASN C CA  1 
ATOM   6446  C C   . ASN B 2 55  ? 167.583 179.249 100.065 1.00 40.29  ? 73   ASN C C   1 
ATOM   6447  O O   . ASN B 2 55  ? 166.599 179.957 99.848  1.00 40.29  ? 73   ASN C O   1 
ATOM   6448  C CB  . ASN B 2 55  ? 169.717 180.129 99.065  1.00 53.59  ? 73   ASN C CB  1 
ATOM   6449  C CG  . ASN B 2 55  ? 170.764 181.189 99.260  1.00 53.59  ? 73   ASN C CG  1 
ATOM   6450  O OD1 . ASN B 2 55  ? 170.576 182.055 100.116 1.00 53.59  ? 73   ASN C OD1 1 
ATOM   6451  N ND2 . ASN B 2 55  ? 171.842 181.144 98.515  1.00 53.59  ? 73   ASN C ND2 1 
ATOM   6452  N N   . ARG B 2 56  ? 167.513 177.927 100.138 1.00 40.29  ? 74   ARG C N   1 
ATOM   6453  C CA  . ARG B 2 56  ? 166.285 177.182 99.942  1.00 40.29  ? 74   ARG C CA  1 
ATOM   6454  C C   . ARG B 2 56  ? 165.524 176.906 101.252 1.00 40.29  ? 74   ARG C C   1 
ATOM   6455  O O   . ARG B 2 56  ? 164.508 176.207 101.237 1.00 40.29  ? 74   ARG C O   1 
ATOM   6456  C CB  . ARG B 2 56  ? 166.618 175.866 99.271  1.00 53.91  ? 74   ARG C CB  1 
ATOM   6457  C CG  . ARG B 2 56  ? 167.165 176.010 97.867  1.00 53.91  ? 74   ARG C CG  1 
ATOM   6458  C CD  . ARG B 2 56  ? 167.713 174.739 97.348  1.00 53.91  ? 74   ARG C CD  1 
ATOM   6459  N NE  . ARG B 2 56  ? 166.687 173.719 97.165  1.00 53.91  ? 74   ARG C NE  1 
ATOM   6460  C CZ  . ARG B 2 56  ? 166.928 172.431 96.838  1.00 53.91  ? 74   ARG C CZ  1 
ATOM   6461  N NH1 . ARG B 2 56  ? 165.915 171.592 96.700  1.00 53.91  ? 74   ARG C NH1 1 
ATOM   6462  N NH2 . ARG B 2 56  ? 168.163 172.008 96.654  1.00 53.91  ? 74   ARG C NH2 1 
ATOM   6463  N N   . ASP B 2 57  ? 166.031 177.404 102.383 1.00 40.29  ? 75   ASP C N   1 
ATOM   6464  C CA  . ASP B 2 57  ? 165.453 177.197 103.704 1.00 40.29  ? 75   ASP C CA  1 
ATOM   6465  C C   . ASP B 2 57  ? 164.235 178.113 103.910 1.00 40.29  ? 75   ASP C C   1 
ATOM   6466  O O   . ASP B 2 57  ? 164.342 179.323 103.720 1.00 40.29  ? 75   ASP C O   1 
ATOM   6467  C CB  . ASP B 2 57  ? 166.494 177.423 104.809 1.00 51.30  ? 75   ASP C CB  1 
ATOM   6468  C CG  . ASP B 2 57  ? 166.000 177.086 106.210 1.00 51.30  ? 75   ASP C CG  1 
ATOM   6469  O OD1 . ASP B 2 57  ? 164.932 177.556 106.576 1.00 51.30  ? 75   ASP C OD1 1 
ATOM   6470  O OD2 . ASP B 2 57  ? 166.674 176.363 106.910 1.00 51.30  ? 75   ASP C OD2 1 
ATOM   6471  N N   . PRO B 2 58  ? 163.030 177.584 104.171 1.00 40.29  ? 76   PRO C N   1 
ATOM   6472  C CA  . PRO B 2 58  ? 161.803 178.348 104.336 1.00 40.29  ? 76   PRO C CA  1 
ATOM   6473  C C   . PRO B 2 58  ? 161.743 179.220 105.600 1.00 40.29  ? 76   PRO C C   1 
ATOM   6474  O O   . PRO B 2 58  ? 160.861 180.073 105.712 1.00 40.29  ? 76   PRO C O   1 
ATOM   6475  C CB  . PRO B 2 58  ? 160.734 177.245 104.371 1.00 68.85  ? 76   PRO C CB  1 
ATOM   6476  C CG  . PRO B 2 58  ? 161.456 176.011 104.870 1.00 68.85  ? 76   PRO C CG  1 
ATOM   6477  C CD  . PRO B 2 58  ? 162.862 176.120 104.333 1.00 68.85  ? 76   PRO C CD  1 
ATOM   6478  N N   . HIS B 2 59  ? 162.632 178.985 106.568 1.00 40.29  ? 77   HIS C N   1 
ATOM   6479  C CA  . HIS B 2 59  ? 162.570 179.735 107.815 1.00 40.29  ? 77   HIS C CA  1 
ATOM   6480  C C   . HIS B 2 59  ? 163.772 180.638 108.049 1.00 40.29  ? 77   HIS C C   1 
ATOM   6481  O O   . HIS B 2 59  ? 163.644 181.679 108.693 1.00 40.29  ? 77   HIS C O   1 
ATOM   6482  C CB  . HIS B 2 59  ? 162.501 178.763 108.984 1.00 54.79  ? 77   HIS C CB  1 
ATOM   6483  C CG  . HIS B 2 59  ? 161.352 177.865 108.911 1.00 54.79  ? 77   HIS C CG  1 
ATOM   6484  N ND1 . HIS B 2 59  ? 160.060 178.288 109.090 1.00 54.79  ? 77   HIS C ND1 1 
ATOM   6485  C CD2 . HIS B 2 59  ? 161.291 176.544 108.668 1.00 54.79  ? 77   HIS C CD2 1 
ATOM   6486  C CE1 . HIS B 2 59  ? 159.247 177.261 108.953 1.00 54.79  ? 77   HIS C CE1 1 
ATOM   6487  N NE2 . HIS B 2 59  ? 159.972 176.187 108.697 1.00 54.79  ? 77   HIS C NE2 1 
ATOM   6488  N N   . LEU B 2 60  ? 164.926 180.248 107.526 1.00 40.29  ? 78   LEU C N   1 
ATOM   6489  C CA  . LEU B 2 60  ? 166.159 180.997 107.733 1.00 40.29  ? 78   LEU C CA  1 
ATOM   6490  C C   . LEU B 2 60  ? 166.465 181.900 106.566 1.00 40.29  ? 78   LEU C C   1 
ATOM   6491  O O   . LEU B 2 60  ? 166.748 181.433 105.469 1.00 40.29  ? 78   LEU C O   1 
ATOM   6492  C CB  . LEU B 2 60  ? 167.321 180.021 107.942 1.00 57.27  ? 78   LEU C CB  1 
ATOM   6493  C CG  . LEU B 2 60  ? 168.731 180.605 108.060 1.00 57.27  ? 78   LEU C CG  1 
ATOM   6494  C CD1 . LEU B 2 60  ? 168.832 181.502 109.254 1.00 57.27  ? 78   LEU C CD1 1 
ATOM   6495  C CD2 . LEU B 2 60  ? 169.702 179.442 108.164 1.00 57.27  ? 78   LEU C CD2 1 
ATOM   6496  N N   . LEU B 2 61  ? 166.453 183.203 106.819 1.00 40.29  ? 79   LEU C N   1 
ATOM   6497  C CA  . LEU B 2 61  ? 166.662 184.193 105.790 1.00 40.29  ? 79   LEU C CA  1 
ATOM   6498  C C   . LEU B 2 61  ? 165.820 184.015 104.531 1.00 40.29  ? 79   LEU C C   1 
ATOM   6499  O O   . LEU B 2 61  ? 166.346 184.159 103.431 1.00 40.29  ? 79   LEU C O   1 
ATOM   6500  C CB  . LEU B 2 61  ? 168.129 184.167 105.360 1.00 57.27  ? 79   LEU C CB  1 
ATOM   6501  C CG  . LEU B 2 61  ? 169.169 184.482 106.401 1.00 57.27  ? 79   LEU C CG  1 
ATOM   6502  C CD1 . LEU B 2 61  ? 170.486 184.265 105.788 1.00 57.27  ? 79   LEU C CD1 1 
ATOM   6503  C CD2 . LEU B 2 61  ? 169.054 185.913 106.849 1.00 57.27  ? 79   LEU C CD2 1 
ATOM   6504  N N   . PRO B 2 62  ? 164.490 183.866 104.616 1.00 40.29  ? 80   PRO C N   1 
ATOM   6505  C CA  . PRO B 2 62  ? 163.636 183.691 103.458 1.00 40.29  ? 80   PRO C CA  1 
ATOM   6506  C C   . PRO B 2 62  ? 163.664 184.922 102.538 1.00 40.29  ? 80   PRO C C   1 
ATOM   6507  O O   . PRO B 2 62  ? 163.370 184.821 101.349 1.00 40.29  ? 80   PRO C O   1 
ATOM   6508  C CB  . PRO B 2 62  ? 162.253 183.477 104.096 1.00 68.85  ? 80   PRO C CB  1 
ATOM   6509  C CG  . PRO B 2 62  ? 162.348 184.124 105.473 1.00 68.85  ? 80   PRO C CG  1 
ATOM   6510  C CD  . PRO B 2 62  ? 163.775 183.898 105.908 1.00 68.85  ? 80   PRO C CD  1 
ATOM   6511  N N   . GLY B 2 63  ? 164.037 186.081 103.098 1.00 40.29  ? 81   GLY C N   1 
ATOM   6512  C CA  . GLY B 2 63  ? 164.109 187.330 102.356 1.00 40.29  ? 81   GLY C CA  1 
ATOM   6513  C C   . GLY B 2 63  ? 165.520 187.722 101.916 1.00 40.29  ? 81   GLY C C   1 
ATOM   6514  O O   . GLY B 2 63  ? 165.735 188.840 101.416 1.00 40.29  ? 81   GLY C O   1 
ATOM   6515  N N   . VAL B 2 64  ? 166.511 186.863 102.182 1.00 40.29  ? 82   VAL C N   1 
ATOM   6516  C CA  . VAL B 2 64  ? 167.875 187.220 101.822 1.00 40.29  ? 82   VAL C CA  1 
ATOM   6517  C C   . VAL B 2 64  ? 168.565 186.108 101.076 1.00 40.29  ? 82   VAL C C   1 
ATOM   6518  O O   . VAL B 2 64  ? 169.006 185.130 101.677 1.00 40.29  ? 82   VAL C O   1 
ATOM   6519  C CB  . VAL B 2 64  ? 168.725 187.506 103.075 1.00 56.74  ? 82   VAL C CB  1 
ATOM   6520  C CG1 . VAL B 2 64  ? 170.157 187.916 102.677 1.00 56.74  ? 82   VAL C CG1 1 
ATOM   6521  C CG2 . VAL B 2 64  ? 168.056 188.536 103.932 1.00 56.74  ? 82   VAL C CG2 1 
ATOM   6522  N N   . ARG B 2 65  ? 168.779 186.280 99.795  1.00 40.29  ? 83   ARG C N   1 
ATOM   6523  C CA  . ARG B 2 65  ? 169.520 185.249 99.122  1.00 40.29  ? 83   ARG C CA  1 
ATOM   6524  C C   . ARG B 2 65  ? 170.977 185.541 99.434  1.00 40.29  ? 83   ARG C C   1 
ATOM   6525  O O   . ARG B 2 65  ? 171.427 186.685 99.290  1.00 40.29  ? 83   ARG C O   1 
ATOM   6526  C CB  . ARG B 2 65  ? 169.224 185.260 97.643  1.00 56.58  ? 83   ARG C CB  1 
ATOM   6527  C CG  . ARG B 2 65  ? 169.855 184.152 96.837  1.00 56.58  ? 83   ARG C CG  1 
ATOM   6528  C CD  . ARG B 2 65  ? 169.380 184.219 95.446  1.00 56.58  ? 83   ARG C CD  1 
ATOM   6529  N NE  . ARG B 2 65  ? 169.947 183.190 94.606  1.00 56.58  ? 83   ARG C NE  1 
ATOM   6530  C CZ  . ARG B 2 65  ? 169.479 181.936 94.463  1.00 56.58  ? 83   ARG C CZ  1 
ATOM   6531  N NH1 . ARG B 2 65  ? 170.095 181.135 93.616  1.00 56.58  ? 83   ARG C NH1 1 
ATOM   6532  N NH2 . ARG B 2 65  ? 168.424 181.511 95.143  1.00 56.58  ? 83   ARG C NH2 1 
ATOM   6533  N N   . LEU B 2 66  ? 171.723 184.537 99.854  1.00 40.29  ? 84   LEU C N   1 
ATOM   6534  C CA  . LEU B 2 66  ? 173.118 184.756 100.164 1.00 40.29  ? 84   LEU C CA  1 
ATOM   6535  C C   . LEU B 2 66  ? 174.025 184.461 99.003  1.00 40.29  ? 84   LEU C C   1 
ATOM   6536  O O   . LEU B 2 66  ? 174.061 183.339 98.480  1.00 40.29  ? 84   LEU C O   1 
ATOM   6537  C CB  . LEU B 2 66  ? 173.552 183.885 101.342 1.00 57.27  ? 84   LEU C CB  1 
ATOM   6538  C CG  . LEU B 2 66  ? 172.843 184.122 102.675 1.00 57.27  ? 84   LEU C CG  1 
ATOM   6539  C CD1 . LEU B 2 66  ? 173.336 183.064 103.674 1.00 57.27  ? 84   LEU C CD1 1 
ATOM   6540  C CD2 . LEU B 2 66  ? 173.150 185.539 103.180 1.00 57.27  ? 84   LEU C CD2 1 
ATOM   6541  N N   . GLY B 2 67  ? 174.752 185.492 98.607  1.00 40.29  ? 85   GLY C N   1 
ATOM   6542  C CA  . GLY B 2 67  ? 175.686 185.417 97.521  1.00 40.29  ? 85   GLY C CA  1 
ATOM   6543  C C   . GLY B 2 67  ? 177.016 185.150 98.157  1.00 40.29  ? 85   GLY C C   1 
ATOM   6544  O O   . GLY B 2 67  ? 177.078 184.944 99.377  1.00 40.29  ? 85   GLY C O   1 
ATOM   6545  N N   . ALA B 2 68  ? 178.085 185.156 97.378  1.00 40.29  ? 86   ALA C N   1 
ATOM   6546  C CA  . ALA B 2 68  ? 179.363 184.885 98.000  1.00 40.29  ? 86   ALA C CA  1 
ATOM   6547  C C   . ALA B 2 68  ? 180.568 185.294 97.196  1.00 40.29  ? 86   ALA C C   1 
ATOM   6548  O O   . ALA B 2 68  ? 180.534 185.339 95.966  1.00 40.29  ? 86   ALA C O   1 
ATOM   6549  C CB  . ALA B 2 68  ? 179.487 183.414 98.309  1.00 54.43  ? 86   ALA C CB  1 
ATOM   6550  N N   . HIS B 2 69  ? 181.659 185.509 97.919  1.00 40.29  ? 87   HIS C N   1 
ATOM   6551  C CA  . HIS B 2 69  ? 182.995 185.706 97.345  1.00 40.29  ? 87   HIS C CA  1 
ATOM   6552  C C   . HIS B 2 69  ? 183.957 184.867 98.135  1.00 40.29  ? 87   HIS C C   1 
ATOM   6553  O O   . HIS B 2 69  ? 184.466 185.326 99.168  1.00 40.29  ? 87   HIS C O   1 
ATOM   6554  C CB  . HIS B 2 69  ? 183.498 187.151 97.380  1.00 53.51  ? 87   HIS C CB  1 
ATOM   6555  C CG  . HIS B 2 69  ? 182.711 188.129 96.607  1.00 53.51  ? 87   HIS C CG  1 
ATOM   6556  N ND1 . HIS B 2 69  ? 182.657 188.114 95.240  1.00 53.51  ? 87   HIS C ND1 1 
ATOM   6557  C CD2 . HIS B 2 69  ? 181.998 189.199 96.998  1.00 53.51  ? 87   HIS C CD2 1 
ATOM   6558  C CE1 . HIS B 2 69  ? 181.920 189.120 94.820  1.00 53.51  ? 87   HIS C CE1 1 
ATOM   6559  N NE2 . HIS B 2 69  ? 181.510 189.799 95.868  1.00 53.51  ? 87   HIS C NE2 1 
ATOM   6560  N N   . ILE B 2 70  ? 184.177 183.650 97.693  1.00 40.29  ? 88   ILE C N   1 
ATOM   6561  C CA  . ILE B 2 70  ? 184.978 182.754 98.469  1.00 40.29  ? 88   ILE C CA  1 
ATOM   6562  C C   . ILE B 2 70  ? 186.333 182.672 97.845  1.00 40.29  ? 88   ILE C C   1 
ATOM   6563  O O   . ILE B 2 70  ? 186.505 182.249 96.715  1.00 40.29  ? 88   ILE C O   1 
ATOM   6564  C CB  . ILE B 2 70  ? 184.332 181.406 98.545  1.00 57.27  ? 88   ILE C CB  1 
ATOM   6565  C CG1 . ILE B 2 70  ? 182.840 181.573 98.998  1.00 57.27  ? 88   ILE C CG1 1 
ATOM   6566  C CG2 . ILE B 2 70  ? 185.126 180.553 99.528  1.00 57.27  ? 88   ILE C CG2 1 
ATOM   6567  C CD1 . ILE B 2 70  ? 182.597 182.234 100.337 1.00 57.27  ? 88   ILE C CD1 1 
ATOM   6568  N N   . LEU B 2 71  ? 187.286 183.042 98.615  1.00 40.29  ? 89   LEU C N   1 
ATOM   6569  C CA  . LEU B 2 71  ? 188.630 183.214 98.206  1.00 40.29  ? 89   LEU C CA  1 
ATOM   6570  C C   . LEU B 2 71  ? 189.478 181.986 98.407  1.00 40.29  ? 89   LEU C C   1 
ATOM   6571  O O   . LEU B 2 71  ? 189.158 181.107 99.221  1.00 40.29  ? 89   LEU C O   1 
ATOM   6572  C CB  . LEU B 2 71  ? 189.093 184.358 99.043  1.00 57.27  ? 89   LEU C CB  1 
ATOM   6573  C CG  . LEU B 2 71  ? 188.231 185.635 98.943  1.00 57.27  ? 89   LEU C CG  1 
ATOM   6574  C CD1 . LEU B 2 71  ? 188.748 186.579 99.952  1.00 57.27  ? 89   LEU C CD1 1 
ATOM   6575  C CD2 . LEU B 2 71  ? 188.227 186.199 97.536  1.00 57.27  ? 89   LEU C CD2 1 
ATOM   6576  N N   . ASP B 2 72  ? 190.544 181.907 97.619  1.00 40.29  ? 90   ASP C N   1 
ATOM   6577  C CA  . ASP B 2 72  ? 191.512 180.823 97.689  1.00 40.29  ? 90   ASP C CA  1 
ATOM   6578  C C   . ASP B 2 72  ? 192.693 181.225 98.527  1.00 40.29  ? 90   ASP C C   1 
ATOM   6579  O O   . ASP B 2 72  ? 193.543 181.994 98.086  1.00 40.29  ? 90   ASP C O   1 
ATOM   6580  C CB  . ASP B 2 72  ? 192.033 180.459 96.308  1.00 51.30  ? 90   ASP C CB  1 
ATOM   6581  C CG  . ASP B 2 72  ? 192.998 179.236 96.308  1.00 51.30  ? 90   ASP C CG  1 
ATOM   6582  O OD1 . ASP B 2 72  ? 193.325 178.647 97.377  1.00 51.30  ? 90   ASP C OD1 1 
ATOM   6583  O OD2 . ASP B 2 72  ? 193.363 178.861 95.223  1.00 51.30  ? 90   ASP C OD2 1 
ATOM   6584  N N   . SER B 2 73  ? 192.803 180.707 99.726  1.00 40.29  ? 91   SER C N   1 
ATOM   6585  C CA  . SER B 2 73  ? 193.912 181.186 100.554 1.00 40.29  ? 91   SER C CA  1 
ATOM   6586  C C   . SER B 2 73  ? 195.278 180.814 99.996  1.00 40.29  ? 91   SER C C   1 
ATOM   6587  O O   . SER B 2 73  ? 196.274 181.383 100.450 1.00 40.29  ? 91   SER C O   1 
ATOM   6588  C CB  . SER B 2 73  ? 193.852 180.639 101.963 1.00 53.66  ? 91   SER C CB  1 
ATOM   6589  O OG  . SER B 2 73  ? 194.251 179.315 101.998 1.00 53.66  ? 91   SER C OG  1 
ATOM   6590  N N   . CYS B 2 74  ? 195.376 179.783 99.095  1.00 40.29  ? 92   CYS C N   1 
ATOM   6591  C CA  . CYS B 2 74  ? 196.596 179.271 98.465  1.00 40.29  ? 92   CYS C CA  1 
ATOM   6592  C C   . CYS B 2 74  ? 197.548 178.749 99.579  1.00 40.29  ? 92   CYS C C   1 
ATOM   6593  O O   . CYS B 2 74  ? 198.739 178.500 99.373  1.00 40.29  ? 92   CYS C O   1 
ATOM   6594  C CB  . CYS B 2 74  ? 197.177 180.417 97.571  1.00 52.21  ? 92   CYS C CB  1 
ATOM   6595  S SG  . CYS B 2 74  ? 198.509 180.073 96.505  1.00 52.21  ? 92   CYS C SG  1 
ATOM   6596  N N   . SER B 2 75  ? 196.974 178.627 100.784 1.00 40.29  ? 93   SER C N   1 
ATOM   6597  C CA  . SER B 2 75  ? 197.615 178.256 102.023 1.00 40.29  ? 93   SER C CA  1 
ATOM   6598  C C   . SER B 2 75  ? 198.740 179.233 102.377 1.00 40.29  ? 93   SER C C   1 
ATOM   6599  O O   . SER B 2 75  ? 199.655 178.886 103.125 1.00 40.29  ? 93   SER C O   1 
ATOM   6600  C CB  . SER B 2 75  ? 198.133 176.833 101.948 1.00 53.66  ? 93   SER C CB  1 
ATOM   6601  O OG  . SER B 2 75  ? 197.083 175.908 101.764 1.00 53.66  ? 93   SER C OG  1 
ATOM   6602  N N   . LYS B 2 76  ? 198.615 180.493 101.941 1.00 40.29  ? 94   LYS C N   1 
ATOM   6603  C CA  . LYS B 2 76  ? 199.617 181.512 102.223 1.00 40.29  ? 94   LYS C CA  1 
ATOM   6604  C C   . LYS B 2 76  ? 198.981 182.776 102.794 1.00 40.29  ? 94   LYS C C   1 
ATOM   6605  O O   . LYS B 2 76  ? 197.820 183.097 102.528 1.00 40.29  ? 94   LYS C O   1 
ATOM   6606  C CB  . LYS B 2 76  ? 200.442 181.835 100.960 1.00 57.63  ? 94   LYS C CB  1 
ATOM   6607  C CG  . LYS B 2 76  ? 201.306 180.648 100.457 1.00 57.63  ? 94   LYS C CG  1 
ATOM   6608  C CD  . LYS B 2 76  ? 202.230 180.968 99.234  1.00 57.63  ? 94   LYS C CD  1 
ATOM   6609  C CE  . LYS B 2 76  ? 203.546 181.682 99.646  1.00 57.63  ? 94   LYS C CE  1 
ATOM   6610  N NZ  . LYS B 2 76  ? 204.586 181.788 98.494  1.00 57.63  ? 94   LYS C NZ  1 
ATOM   6611  N N   . ASP B 2 77  ? 199.760 183.507 103.575 1.00 40.29  ? 95   ASP C N   1 
ATOM   6612  C CA  . ASP B 2 77  ? 199.310 184.741 104.180 1.00 40.29  ? 95   ASP C CA  1 
ATOM   6613  C C   . ASP B 2 77  ? 199.208 185.861 103.166 1.00 40.29  ? 95   ASP C C   1 
ATOM   6614  O O   . ASP B 2 77  ? 198.311 186.706 103.238 1.00 40.29  ? 95   ASP C O   1 
ATOM   6615  C CB  . ASP B 2 77  ? 200.302 185.074 105.275 1.00 51.30  ? 95   ASP C CB  1 
ATOM   6616  C CG  . ASP B 2 77  ? 201.738 185.061 104.709 1.00 51.30  ? 95   ASP C CG  1 
ATOM   6617  O OD1 . ASP B 2 77  ? 201.912 184.595 103.563 1.00 51.30  ? 95   ASP C OD1 1 
ATOM   6618  O OD2 . ASP B 2 77  ? 202.631 185.475 105.390 1.00 51.30  ? 95   ASP C OD2 1 
ATOM   6619  N N   . THR B 2 78  ? 200.089 185.814 102.188 1.00 40.29  ? 96   THR C N   1 
ATOM   6620  C CA  . THR B 2 78  ? 200.114 186.812 101.148 1.00 40.29  ? 96   THR C CA  1 
ATOM   6621  C C   . THR B 2 78  ? 198.808 186.793 100.398 1.00 40.29  ? 96   THR C C   1 
ATOM   6622  O O   . THR B 2 78  ? 198.184 187.840 100.229 1.00 40.29  ? 96   THR C O   1 
ATOM   6623  C CB  . THR B 2 78  ? 201.289 186.570 100.187 1.00 55.15  ? 96   THR C CB  1 
ATOM   6624  O OG1 . THR B 2 78  ? 202.526 186.712 100.903 1.00 55.15  ? 96   THR C OG1 1 
ATOM   6625  C CG2 . THR B 2 78  ? 201.241 187.558 99.041  1.00 55.15  ? 96   THR C CG2 1 
ATOM   6626  N N   . HIS B 2 79  ? 198.354 185.604 100.017 1.00 40.29  ? 97   HIS C N   1 
ATOM   6627  C CA  . HIS B 2 79  ? 197.099 185.491 99.308  1.00 40.29  ? 97   HIS C CA  1 
ATOM   6628  C C   . HIS B 2 79  ? 195.941 185.774 100.184 1.00 40.29  ? 97   HIS C C   1 
ATOM   6629  O O   . HIS B 2 79  ? 194.990 186.440 99.771  1.00 40.29  ? 97   HIS C O   1 
ATOM   6630  C CB  . HIS B 2 79  ? 196.949 184.128 98.666  1.00 53.51  ? 97   HIS C CB  1 
ATOM   6631  C CG  . HIS B 2 79  ? 197.553 184.110 97.373  1.00 53.51  ? 97   HIS C CG  1 
ATOM   6632  N ND1 . HIS B 2 79  ? 196.868 184.554 96.262  1.00 53.51  ? 97   HIS C ND1 1 
ATOM   6633  C CD2 . HIS B 2 79  ? 198.794 183.782 96.951  1.00 53.51  ? 97   HIS C CD2 1 
ATOM   6634  C CE1 . HIS B 2 79  ? 197.662 184.489 95.206  1.00 53.51  ? 97   HIS C CE1 1 
ATOM   6635  N NE2 . HIS B 2 79  ? 198.833 184.033 95.594  1.00 53.51  ? 97   HIS C NE2 1 
ATOM   6636  N N   . ALA B 2 80  ? 196.019 185.371 101.438 1.00 40.29  ? 98   ALA C N   1 
ATOM   6637  C CA  . ALA B 2 80  ? 194.897 185.643 102.275 1.00 40.29  ? 98   ALA C CA  1 
ATOM   6638  C C   . ALA B 2 80  ? 194.600 187.121 102.307 1.00 40.29  ? 98   ALA C C   1 
ATOM   6639  O O   . ALA B 2 80  ? 193.438 187.499 102.237 1.00 40.29  ? 98   ALA C O   1 
ATOM   6640  C CB  . ALA B 2 80  ? 195.182 185.169 103.664 1.00 54.43  ? 98   ALA C CB  1 
ATOM   6641  N N   . LEU B 2 81  ? 195.611 187.984 102.324 1.00 40.29  ? 99   LEU C N   1 
ATOM   6642  C CA  . LEU B 2 81  ? 195.244 189.384 102.365 1.00 40.29  ? 99   LEU C CA  1 
ATOM   6643  C C   . LEU B 2 81  ? 195.065 189.987 100.996 1.00 40.29  ? 99   LEU C C   1 
ATOM   6644  O O   . LEU B 2 81  ? 194.203 190.855 100.818 1.00 40.29  ? 99   LEU C O   1 
ATOM   6645  C CB  . LEU B 2 81  ? 196.246 190.196 103.148 1.00 57.27  ? 99   LEU C CB  1 
ATOM   6646  C CG  . LEU B 2 81  ? 196.443 189.774 104.602 1.00 57.27  ? 99   LEU C CG  1 
ATOM   6647  C CD1 . LEU B 2 81  ? 197.433 190.757 105.245 1.00 57.27  ? 99   LEU C CD1 1 
ATOM   6648  C CD2 . LEU B 2 81  ? 195.115 189.700 105.359 1.00 57.27  ? 99   LEU C CD2 1 
ATOM   6649  N N   . GLU B 2 82  ? 195.787 189.505 99.983  1.00 40.29  ? 100  GLU C N   1 
ATOM   6650  C CA  . GLU B 2 82  ? 195.576 190.098 98.676  1.00 40.29  ? 100  GLU C CA  1 
ATOM   6651  C C   . GLU B 2 82  ? 194.137 189.881 98.299  1.00 40.29  ? 100  GLU C C   1 
ATOM   6652  O O   . GLU B 2 82  ? 193.484 190.762 97.737  1.00 40.29  ? 100  GLU C O   1 
ATOM   6653  C CB  . GLU B 2 82  ? 196.431 189.440 97.584  1.00 53.10  ? 100  GLU C CB  1 
ATOM   6654  C CG  . GLU B 2 82  ? 197.905 189.740 97.599  1.00 53.10  ? 100  GLU C CG  1 
ATOM   6655  C CD  . GLU B 2 82  ? 198.671 188.974 96.572  1.00 53.10  ? 100  GLU C CD  1 
ATOM   6656  O OE1 . GLU B 2 82  ? 198.069 188.219 95.850  1.00 53.10  ? 100  GLU C OE1 1 
ATOM   6657  O OE2 . GLU B 2 82  ? 199.866 189.143 96.503  1.00 53.10  ? 100  GLU C OE2 1 
ATOM   6658  N N   . GLN B 2 83  ? 193.627 188.709 98.637  1.00 40.29  ? 101  GLN C N   1 
ATOM   6659  C CA  . GLN B 2 83  ? 192.279 188.394 98.309  1.00 40.29  ? 101  GLN C CA  1 
ATOM   6660  C C   . GLN B 2 83  ? 191.277 188.852 99.373  1.00 40.29  ? 101  GLN C C   1 
ATOM   6661  O O   . GLN B 2 83  ? 190.190 189.294 99.027  1.00 40.29  ? 101  GLN C O   1 
ATOM   6662  C CB  . GLN B 2 83  ? 192.175 186.892 98.082  1.00 54.76  ? 101  GLN C CB  1 
ATOM   6663  C CG  . GLN B 2 83  ? 192.945 186.363 96.864  1.00 54.76  ? 101  GLN C CG  1 
ATOM   6664  C CD  . GLN B 2 83  ? 192.749 184.860 96.721  1.00 54.76  ? 101  GLN C CD  1 
ATOM   6665  O OE1 . GLN B 2 83  ? 191.572 184.398 96.708  1.00 54.76  ? 101  GLN C OE1 1 
ATOM   6666  N NE2 . GLN B 2 83  ? 193.844 184.098 96.632  1.00 54.76  ? 101  GLN C NE2 1 
ATOM   6667  N N   . ALA B 2 84  ? 191.606 188.831 100.675 1.00 40.29  ? 102  ALA C N   1 
ATOM   6668  C CA  . ALA B 2 84  ? 190.609 189.239 101.674 1.00 40.29  ? 102  ALA C CA  1 
ATOM   6669  C C   . ALA B 2 84  ? 190.205 190.664 101.457 1.00 40.29  ? 102  ALA C C   1 
ATOM   6670  O O   . ALA B 2 84  ? 189.036 191.024 101.616 1.00 40.29  ? 102  ALA C O   1 
ATOM   6671  C CB  . ALA B 2 84  ? 191.123 189.089 103.087 1.00 54.43  ? 102  ALA C CB  1 
ATOM   6672  N N   . LEU B 2 85  ? 191.159 191.464 101.014 1.00 40.29  ? 103  LEU C N   1 
ATOM   6673  C CA  . LEU B 2 85  ? 190.953 192.863 100.773 1.00 40.29  ? 103  LEU C CA  1 
ATOM   6674  C C   . LEU B 2 85  ? 189.916 193.084 99.677  1.00 40.29  ? 103  LEU C C   1 
ATOM   6675  O O   . LEU B 2 85  ? 189.330 194.164 99.582  1.00 40.29  ? 103  LEU C O   1 
ATOM   6676  C CB  . LEU B 2 85  ? 192.286 193.512 100.415 1.00 57.27  ? 103  LEU C CB  1 
ATOM   6677  C CG  . LEU B 2 85  ? 192.339 195.061 100.358 1.00 57.27  ? 103  LEU C CG  1 
ATOM   6678  C CD1 . LEU B 2 85  ? 191.972 195.695 101.743 1.00 57.27  ? 103  LEU C CD1 1 
ATOM   6679  C CD2 . LEU B 2 85  ? 193.751 195.469 99.941  1.00 57.27  ? 103  LEU C CD2 1 
ATOM   6680  N N   . ASP B 2 86  ? 189.705 192.087 98.816  1.00 40.29  ? 104  ASP C N   1 
ATOM   6681  C CA  . ASP B 2 86  ? 188.774 192.176 97.712  1.00 40.29  ? 104  ASP C CA  1 
ATOM   6682  C C   . ASP B 2 86  ? 187.359 192.264 98.246  1.00 40.29  ? 104  ASP C C   1 
ATOM   6683  O O   . ASP B 2 86  ? 186.460 192.756 97.568  1.00 40.29  ? 104  ASP C O   1 
ATOM   6684  C CB  . ASP B 2 86  ? 188.897 190.967 96.782  1.00 51.71  ? 104  ASP C CB  1 
ATOM   6685  C CG  . ASP B 2 86  ? 188.247 191.191 95.400  1.00 51.71  ? 104  ASP C CG  1 
ATOM   6686  O OD1 . ASP B 2 86  ? 188.691 192.083 94.695  1.00 51.71  ? 104  ASP C OD1 1 
ATOM   6687  O OD2 . ASP B 2 86  ? 187.337 190.477 95.048  1.00 51.71  ? 104  ASP C OD2 1 
ATOM   6688  N N   . PHE B 2 87  ? 187.131 191.802 99.477  1.00 40.29  ? 105  PHE C N   1 
ATOM   6689  C CA  . PHE B 2 87  ? 185.791 191.843 100.000 1.00 40.29  ? 105  PHE C CA  1 
ATOM   6690  C C   . PHE B 2 87  ? 185.528 193.203 100.588 1.00 40.29  ? 105  PHE C C   1 
ATOM   6691  O O   . PHE B 2 87  ? 184.395 193.570 100.894 1.00 40.29  ? 105  PHE C O   1 
ATOM   6692  C CB  . PHE B 2 87  ? 185.568 190.781 101.054 1.00 54.49  ? 105  PHE C CB  1 
ATOM   6693  C CG  . PHE B 2 87  ? 184.138 190.690 101.427 1.00 54.49  ? 105  PHE C CG  1 
ATOM   6694  C CD1 . PHE B 2 87  ? 183.208 190.142 100.562 1.00 54.49  ? 105  PHE C CD1 1 
ATOM   6695  C CD2 . PHE B 2 87  ? 183.707 191.180 102.639 1.00 54.49  ? 105  PHE C CD2 1 
ATOM   6696  C CE1 . PHE B 2 87  ? 181.877 190.092 100.908 1.00 54.49  ? 105  PHE C CE1 1 
ATOM   6697  C CE2 . PHE B 2 87  ? 182.381 191.130 102.988 1.00 54.49  ? 105  PHE C CE2 1 
ATOM   6698  C CZ  . PHE B 2 87  ? 181.466 190.585 102.120 1.00 54.49  ? 105  PHE C CZ  1 
ATOM   6699  N N   . VAL B 2 88  ? 186.584 193.974 100.754 1.00 40.29  ? 106  VAL C N   1 
ATOM   6700  C CA  . VAL B 2 88  ? 186.430 195.287 101.285 1.00 40.29  ? 106  VAL C CA  1 
ATOM   6701  C C   . VAL B 2 88  ? 186.103 196.134 100.078 1.00 40.29  ? 106  VAL C C   1 
ATOM   6702  O O   . VAL B 2 88  ? 185.133 196.888 100.064 1.00 40.29  ? 106  VAL C O   1 
ATOM   6703  C CB  . VAL B 2 88  ? 187.718 195.737 101.965 1.00 56.74  ? 106  VAL C CB  1 
ATOM   6704  C CG1 . VAL B 2 88  ? 187.584 197.154 102.428 1.00 56.74  ? 106  VAL C CG1 1 
ATOM   6705  C CG2 . VAL B 2 88  ? 188.026 194.771 103.115 1.00 56.74  ? 106  VAL C CG2 1 
ATOM   6706  N N   . ARG B 2 89  ? 186.888 195.933 99.020  1.00 40.29  ? 107  ARG C N   1 
ATOM   6707  C CA  . ARG B 2 89  ? 186.712 196.639 97.762  1.00 40.29  ? 107  ARG C CA  1 
ATOM   6708  C C   . ARG B 2 89  ? 185.300 196.408 97.230  1.00 40.29  ? 107  ARG C C   1 
ATOM   6709  O O   . ARG B 2 89  ? 184.645 197.334 96.751  1.00 40.29  ? 107  ARG C O   1 
ATOM   6710  C CB  . ARG B 2 89  ? 187.718 196.148 96.739  1.00 54.42  ? 107  ARG C CB  1 
ATOM   6711  C CG  . ARG B 2 89  ? 187.728 196.905 95.428  1.00 54.42  ? 107  ARG C CG  1 
ATOM   6712  C CD  . ARG B 2 89  ? 188.672 196.293 94.453  1.00 54.42  ? 107  ARG C CD  1 
ATOM   6713  N NE  . ARG B 2 89  ? 188.232 194.959 94.016  1.00 54.42  ? 107  ARG C NE  1 
ATOM   6714  C CZ  . ARG B 2 89  ? 187.304 194.708 93.070  1.00 54.42  ? 107  ARG C CZ  1 
ATOM   6715  N NH1 . ARG B 2 89  ? 187.041 193.452 92.792  1.00 54.42  ? 107  ARG C NH1 1 
ATOM   6716  N NH2 . ARG B 2 89  ? 186.679 195.686 92.431  1.00 54.42  ? 107  ARG C NH2 1 
ATOM   6717  N N   . ALA B 2 90  ? 184.822 195.170 97.369  1.00 40.29  ? 108  ALA C N   1 
ATOM   6718  C CA  . ALA B 2 90  ? 183.490 194.738 96.950  1.00 40.29  ? 108  ALA C CA  1 
ATOM   6719  C C   . ALA B 2 90  ? 182.311 195.463 97.648  1.00 40.29  ? 108  ALA C C   1 
ATOM   6720  O O   . ALA B 2 90  ? 181.189 195.405 97.131  1.00 40.29  ? 108  ALA C O   1 
ATOM   6721  C CB  . ALA B 2 90  ? 183.332 193.244 97.215  1.00 54.43  ? 108  ALA C CB  1 
ATOM   6722  N N   . SER B 2 91  ? 182.531 196.048 98.856  1.00 40.29  ? 109  SER C N   1 
ATOM   6723  C CA  . SER B 2 91  ? 181.527 196.715 99.679  1.00 40.29  ? 109  SER C CA  1 
ATOM   6724  C C   . SER B 2 91  ? 182.253 197.627 100.670 1.00 40.29  ? 109  SER C C   1 
ATOM   6725  O O   . SER B 2 91  ? 181.915 198.807 100.831 1.00 40.29  ? 109  SER C O   1 
ATOM   6726  C CB  . SER B 2 91  ? 180.641 195.680 100.410 1.00 53.66  ? 109  SER C CB  1 
ATOM   6727  O OG  . SER B 2 91  ? 179.694 196.308 101.222 1.00 53.66  ? 109  SER C OG  1 
ATOM   6728  N N   . VAL B 2 121 ? 182.110 187.428 106.916 1.00 40.29  ? 139  VAL C N   1 
ATOM   6729  C CA  . VAL B 2 121 ? 183.051 186.577 106.190 1.00 40.29  ? 139  VAL C CA  1 
ATOM   6730  C C   . VAL B 2 121 ? 183.244 185.239 106.934 1.00 40.29  ? 139  VAL C C   1 
ATOM   6731  O O   . VAL B 2 121 ? 183.438 185.223 108.162 1.00 40.29  ? 139  VAL C O   1 
ATOM   6732  C CB  . VAL B 2 121 ? 184.450 187.327 105.988 1.00 56.74  ? 139  VAL C CB  1 
ATOM   6733  C CG1 . VAL B 2 121 ? 185.590 186.388 105.313 1.00 56.74  ? 139  VAL C CG1 1 
ATOM   6734  C CG2 . VAL B 2 121 ? 184.259 188.616 105.030 1.00 56.74  ? 139  VAL C CG2 1 
ATOM   6735  N N   . ILE B 2 122 ? 183.193 184.115 106.175 1.00 40.29  ? 140  ILE C N   1 
ATOM   6736  C CA  . ILE B 2 122 ? 183.396 182.760 106.696 1.00 40.29  ? 140  ILE C CA  1 
ATOM   6737  C C   . ILE B 2 122 ? 184.710 182.231 106.189 1.00 40.29  ? 140  ILE C C   1 
ATOM   6738  O O   . ILE B 2 122 ? 184.856 181.904 105.013 1.00 40.29  ? 140  ILE C O   1 
ATOM   6739  C CB  . ILE B 2 122 ? 182.260 181.853 106.247 1.00 57.27  ? 140  ILE C CB  1 
ATOM   6740  C CG1 . ILE B 2 122 ? 180.924 182.468 106.768 1.00 57.27  ? 140  ILE C CG1 1 
ATOM   6741  C CG2 . ILE B 2 122 ? 182.510 180.416 106.778 1.00 57.27  ? 140  ILE C CG2 1 
ATOM   6742  C CD1 . ILE B 2 122 ? 179.726 181.844 106.262 1.00 57.27  ? 140  ILE C CD1 1 
ATOM   6743  N N   . GLY B 2 123 ? 185.657 182.064 107.062 1.00 40.29  ? 141  GLY C N   1 
ATOM   6744  C CA  . GLY B 2 123 ? 186.940 181.655 106.556 1.00 40.29  ? 141  GLY C CA  1 
ATOM   6745  C C   . GLY B 2 123 ? 187.991 181.561 107.616 1.00 40.29  ? 141  GLY C C   1 
ATOM   6746  O O   . GLY B 2 123 ? 187.883 182.145 108.696 1.00 40.29  ? 141  GLY C O   1 
ATOM   6747  N N   . GLY B 2 124 ? 189.069 180.901 107.246 1.00 40.29  ? 142  GLY C N   1 
ATOM   6748  C CA  . GLY B 2 124 ? 190.134 180.683 108.172 1.00 40.29  ? 142  GLY C CA  1 
ATOM   6749  C C   . GLY B 2 124 ? 190.137 179.179 108.207 1.00 40.29  ? 142  GLY C C   1 
ATOM   6750  O O   . GLY B 2 124 ? 189.126 178.573 108.521 1.00 40.29  ? 142  GLY C O   1 
ATOM   6751  N N   . SER B 2 125 ? 191.237 178.548 107.851 1.00 40.29  ? 143  SER C N   1 
ATOM   6752  C CA  . SER B 2 125 ? 191.314 177.113 107.964 1.00 40.29  ? 143  SER C CA  1 
ATOM   6753  C C   . SER B 2 125 ? 192.556 176.992 108.741 1.00 40.29  ? 143  SER C C   1 
ATOM   6754  O O   . SER B 2 125 ? 192.510 176.786 109.948 1.00 40.29  ? 143  SER C O   1 
ATOM   6755  C CB  . SER B 2 125 ? 191.454 176.490 106.613 1.00 53.66  ? 143  SER C CB  1 
ATOM   6756  O OG  . SER B 2 125 ? 192.489 177.099 105.871 1.00 53.66  ? 143  SER C OG  1 
ATOM   6757  N N   . TYR B 2 126 ? 193.693 177.146 108.086 1.00 40.29  ? 144  TYR C N   1 
ATOM   6758  C CA  . TYR B 2 126 ? 194.928 177.199 108.828 1.00 40.29  ? 144  TYR C CA  1 
ATOM   6759  C C   . TYR B 2 126 ? 194.844 178.515 109.619 1.00 40.29  ? 144  TYR C C   1 
ATOM   6760  O O   . TYR B 2 126 ? 194.020 179.353 109.282 1.00 40.29  ? 144  TYR C O   1 
ATOM   6761  C CB  . TYR B 2 126 ? 196.099 177.140 107.870 1.00 54.08  ? 144  TYR C CB  1 
ATOM   6762  C CG  . TYR B 2 126 ? 197.434 177.265 108.532 1.00 54.08  ? 144  TYR C CG  1 
ATOM   6763  C CD1 . TYR B 2 126 ? 197.990 178.508 108.773 1.00 54.08  ? 144  TYR C CD1 1 
ATOM   6764  C CD2 . TYR B 2 126 ? 198.143 176.140 108.918 1.00 54.08  ? 144  TYR C CD2 1 
ATOM   6765  C CE1 . TYR B 2 126 ? 199.215 178.629 109.387 1.00 54.08  ? 144  TYR C CE1 1 
ATOM   6766  C CE2 . TYR B 2 126 ? 199.373 176.251 109.532 1.00 54.08  ? 144  TYR C CE2 1 
ATOM   6767  C CZ  . TYR B 2 126 ? 199.903 177.500 109.763 1.00 54.08  ? 144  TYR C CZ  1 
ATOM   6768  O OH  . TYR B 2 126 ? 201.128 177.627 110.372 1.00 54.08  ? 144  TYR C OH  1 
ATOM   6769  N N   . SER B 2 127 ? 195.656 178.730 110.650 1.00 40.29  ? 145  SER C N   1 
ATOM   6770  C CA  . SER B 2 127 ? 195.550 179.903 111.492 1.00 40.29  ? 145  SER C CA  1 
ATOM   6771  C C   . SER B 2 127 ? 196.294 181.154 111.082 1.00 40.29  ? 145  SER C C   1 
ATOM   6772  O O   . SER B 2 127 ? 195.785 182.252 111.293 1.00 40.29  ? 145  SER C O   1 
ATOM   6773  C CB  . SER B 2 127 ? 196.008 179.533 112.869 1.00 53.66  ? 145  SER C CB  1 
ATOM   6774  O OG  . SER B 2 127 ? 197.368 179.214 112.856 1.00 53.66  ? 145  SER C OG  1 
ATOM   6775  N N   . ASP B 2 128 ? 197.397 181.056 110.345 1.00 40.29  ? 146  ASP C N   1 
ATOM   6776  C CA  . ASP B 2 128 ? 198.095 182.304 110.026 1.00 40.29  ? 146  ASP C CA  1 
ATOM   6777  C C   . ASP B 2 128 ? 197.151 183.169 109.234 1.00 40.29  ? 146  ASP C C   1 
ATOM   6778  O O   . ASP B 2 128 ? 197.114 184.397 109.382 1.00 40.29  ? 146  ASP C O   1 
ATOM   6779  C CB  . ASP B 2 128 ? 199.315 182.068 109.159 1.00 51.30  ? 146  ASP C CB  1 
ATOM   6780  C CG  . ASP B 2 128 ? 200.453 181.328 109.861 1.00 51.30  ? 146  ASP C CG  1 
ATOM   6781  O OD1 . ASP B 2 128 ? 200.453 181.245 111.060 1.00 51.30  ? 146  ASP C OD1 1 
ATOM   6782  O OD2 . ASP B 2 128 ? 201.302 180.803 109.158 1.00 51.30  ? 146  ASP C OD2 1 
ATOM   6783  N N   . VAL B 2 129 ? 196.390 182.490 108.400 1.00 40.29  ? 147  VAL C N   1 
ATOM   6784  C CA  . VAL B 2 129 ? 195.401 183.076 107.565 1.00 40.29  ? 147  VAL C CA  1 
ATOM   6785  C C   . VAL B 2 129 ? 194.231 183.598 108.365 1.00 40.29  ? 147  VAL C C   1 
ATOM   6786  O O   . VAL B 2 129 ? 193.831 184.745 108.189 1.00 40.29  ? 147  VAL C O   1 
ATOM   6787  C CB  . VAL B 2 129 ? 194.952 182.022 106.553 1.00 56.74  ? 147  VAL C CB  1 
ATOM   6788  C CG1 . VAL B 2 129 ? 193.756 182.493 105.791 1.00 56.74  ? 147  VAL C CG1 1 
ATOM   6789  C CG2 . VAL B 2 129 ? 196.141 181.752 105.583 1.00 56.74  ? 147  VAL C CG2 1 
ATOM   6790  N N   . SER B 2 130 ? 193.678 182.817 109.289 1.00 40.29  ? 148  SER C N   1 
ATOM   6791  C CA  . SER B 2 130 ? 192.516 183.366 109.971 1.00 40.29  ? 148  SER C CA  1 
ATOM   6792  C C   . SER B 2 130 ? 192.854 184.621 110.772 1.00 40.29  ? 148  SER C C   1 
ATOM   6793  O O   . SER B 2 130 ? 192.046 185.559 110.832 1.00 40.29  ? 148  SER C O   1 
ATOM   6794  C CB  . SER B 2 130 ? 191.922 182.334 110.912 1.00 53.66  ? 148  SER C CB  1 
ATOM   6795  O OG  . SER B 2 130 ? 192.746 182.090 112.017 1.00 53.66  ? 148  SER C OG  1 
ATOM   6796  N N   . ILE B 2 131 ? 194.078 184.693 111.288 1.00 40.29  ? 149  ILE C N   1 
ATOM   6797  C CA  . ILE B 2 131 ? 194.476 185.854 112.064 1.00 40.29  ? 149  ILE C CA  1 
ATOM   6798  C C   . ILE B 2 131 ? 194.660 187.086 111.211 1.00 40.29  ? 149  ILE C C   1 
ATOM   6799  O O   . ILE B 2 131 ? 194.152 188.162 111.546 1.00 40.29  ? 149  ILE C O   1 
ATOM   6800  C CB  . ILE B 2 131 ? 195.807 185.600 112.815 1.00 57.27  ? 149  ILE C CB  1 
ATOM   6801  C CG1 . ILE B 2 131 ? 195.675 184.455 113.881 1.00 57.27  ? 149  ILE C CG1 1 
ATOM   6802  C CG2 . ILE B 2 131 ? 196.303 186.895 113.464 1.00 57.27  ? 149  ILE C CG2 1 
ATOM   6803  C CD1 . ILE B 2 131 ? 194.683 184.694 115.034 1.00 57.27  ? 149  ILE C CD1 1 
ATOM   6804  N N   . GLN B 2 132 ? 195.367 186.961 110.101 1.00 40.29  ? 150  GLN C N   1 
ATOM   6805  C CA  . GLN B 2 132 ? 195.598 188.167 109.355 1.00 40.29  ? 150  GLN C CA  1 
ATOM   6806  C C   . GLN B 2 132 ? 194.355 188.653 108.679 1.00 40.29  ? 150  GLN C C   1 
ATOM   6807  O O   . GLN B 2 132 ? 194.185 189.861 108.478 1.00 40.29  ? 150  GLN C O   1 
ATOM   6808  C CB  . GLN B 2 132 ? 196.745 187.991 108.384 1.00 54.76  ? 150  GLN C CB  1 
ATOM   6809  C CG  . GLN B 2 132 ? 198.038 187.761 109.078 1.00 54.76  ? 150  GLN C CG  1 
ATOM   6810  C CD  . GLN B 2 132 ? 198.315 188.851 110.090 1.00 54.76  ? 150  GLN C CD  1 
ATOM   6811  O OE1 . GLN B 2 132 ? 198.068 190.046 109.857 1.00 54.76  ? 150  GLN C OE1 1 
ATOM   6812  N NE2 . GLN B 2 132 ? 198.828 188.439 111.237 1.00 54.76  ? 150  GLN C NE2 1 
ATOM   6813  N N   . VAL B 2 133 ? 193.471 187.754 108.320 1.00 40.29  ? 151  VAL C N   1 
ATOM   6814  C CA  . VAL B 2 133 ? 192.264 188.215 107.704 1.00 40.29  ? 151  VAL C CA  1 
ATOM   6815  C C   . VAL B 2 133 ? 191.481 189.022 108.706 1.00 40.29  ? 151  VAL C C   1 
ATOM   6816  O O   . VAL B 2 133 ? 190.974 190.096 108.369 1.00 40.29  ? 151  VAL C O   1 
ATOM   6817  C CB  . VAL B 2 133 ? 191.481 187.057 107.145 1.00 56.74  ? 151  VAL C CB  1 
ATOM   6818  C CG1 . VAL B 2 133 ? 190.111 187.502 106.688 1.00 56.74  ? 151  VAL C CG1 1 
ATOM   6819  C CG2 . VAL B 2 133 ? 192.267 186.521 105.993 1.00 56.74  ? 151  VAL C CG2 1 
ATOM   6820  N N   . ALA B 2 134 ? 191.408 188.550 109.948 1.00 40.29  ? 152  ALA C N   1 
ATOM   6821  C CA  . ALA B 2 134 ? 190.695 189.299 110.962 1.00 40.29  ? 152  ALA C CA  1 
ATOM   6822  C C   . ALA B 2 134 ? 191.283 190.701 111.114 1.00 40.29  ? 152  ALA C C   1 
ATOM   6823  O O   . ALA B 2 134 ? 190.537 191.684 111.248 1.00 40.29  ? 152  ALA C O   1 
ATOM   6824  C CB  . ALA B 2 134 ? 190.762 188.559 112.286 1.00 54.43  ? 152  ALA C CB  1 
ATOM   6825  N N   . ASN B 2 135 ? 192.616 190.829 111.001 1.00 40.29  ? 153  ASN C N   1 
ATOM   6826  C CA  . ASN B 2 135 ? 193.214 192.153 111.125 1.00 40.29  ? 153  ASN C CA  1 
ATOM   6827  C C   . ASN B 2 135 ? 192.697 193.130 110.092 1.00 40.29  ? 153  ASN C C   1 
ATOM   6828  O O   . ASN B 2 135 ? 192.562 194.308 110.405 1.00 40.29  ? 153  ASN C O   1 
ATOM   6829  C CB  . ASN B 2 135 ? 194.725 192.117 111.045 1.00 53.59  ? 153  ASN C CB  1 
ATOM   6830  C CG  . ASN B 2 135 ? 195.392 191.717 112.278 1.00 53.59  ? 153  ASN C CG  1 
ATOM   6831  O OD1 . ASN B 2 135 ? 194.828 191.897 113.359 1.00 53.59  ? 153  ASN C OD1 1 
ATOM   6832  N ND2 . ASN B 2 135 ? 196.594 191.203 112.189 1.00 53.59  ? 153  ASN C ND2 1 
ATOM   6833  N N   . LEU B 2 136 ? 192.418 192.685 108.867 1.00 40.29  ? 154  LEU C N   1 
ATOM   6834  C CA  . LEU B 2 136 ? 191.845 193.643 107.927 1.00 40.29  ? 154  LEU C CA  1 
ATOM   6835  C C   . LEU B 2 136 ? 190.361 193.792 108.038 1.00 40.29  ? 154  LEU C C   1 
ATOM   6836  O O   . LEU B 2 136 ? 189.838 194.891 107.950 1.00 40.29  ? 154  LEU C O   1 
ATOM   6837  C CB  . LEU B 2 136 ? 192.047 193.284 106.442 1.00 57.27  ? 154  LEU C CB  1 
ATOM   6838  C CG  . LEU B 2 136 ? 193.404 193.384 105.824 1.00 57.27  ? 154  LEU C CG  1 
ATOM   6839  C CD1 . LEU B 2 136 ? 193.339 192.811 104.367 1.00 57.27  ? 154  LEU C CD1 1 
ATOM   6840  C CD2 . LEU B 2 136 ? 193.803 194.849 105.756 1.00 57.27  ? 154  LEU C CD2 1 
ATOM   6841  N N   . LEU B 2 137 ? 189.644 192.718 108.242 1.00 40.29  ? 155  LEU C N   1 
ATOM   6842  C CA  . LEU B 2 137 ? 188.205 192.856 108.166 1.00 40.29  ? 155  LEU C CA  1 
ATOM   6843  C C   . LEU B 2 137 ? 187.638 193.723 109.250 1.00 40.29  ? 155  LEU C C   1 
ATOM   6844  O O   . LEU B 2 137 ? 186.710 194.511 109.020 1.00 40.29  ? 155  LEU C O   1 
ATOM   6845  C CB  . LEU B 2 137 ? 187.563 191.500 108.211 1.00 57.27  ? 155  LEU C CB  1 
ATOM   6846  C CG  . LEU B 2 137 ? 187.806 190.606 107.026 1.00 57.27  ? 155  LEU C CG  1 
ATOM   6847  C CD1 . LEU B 2 137 ? 187.162 189.314 107.359 1.00 57.27  ? 155  LEU C CD1 1 
ATOM   6848  C CD2 . LEU B 2 137 ? 187.256 191.203 105.706 1.00 57.27  ? 155  LEU C CD2 1 
ATOM   6849  N N   . ARG B 2 138 ? 188.239 193.682 110.419 1.00 40.29  ? 156  ARG C N   1 
ATOM   6850  C CA  . ARG B 2 138 ? 187.718 194.483 111.498 1.00 40.29  ? 156  ARG C CA  1 
ATOM   6851  C C   . ARG B 2 138 ? 187.856 195.972 111.247 1.00 40.29  ? 156  ARG C C   1 
ATOM   6852  O O   . ARG B 2 138 ? 187.121 196.772 111.823 1.00 40.29  ? 156  ARG C O   1 
ATOM   6853  C CB  . ARG B 2 138 ? 188.428 194.174 112.777 1.00 56.58  ? 156  ARG C CB  1 
ATOM   6854  C CG  . ARG B 2 138 ? 189.901 194.597 112.837 1.00 56.58  ? 156  ARG C CG  1 
ATOM   6855  C CD  . ARG B 2 138 ? 190.437 194.211 114.126 1.00 56.58  ? 156  ARG C CD  1 
ATOM   6856  N NE  . ARG B 2 138 ? 189.789 194.989 115.159 1.00 56.58  ? 156  ARG C NE  1 
ATOM   6857  C CZ  . ARG B 2 138 ? 190.239 196.147 115.668 1.00 56.58  ? 156  ARG C CZ  1 
ATOM   6858  N NH1 . ARG B 2 138 ? 189.497 196.801 116.549 1.00 56.58  ? 156  ARG C NH1 1 
ATOM   6859  N NH2 . ARG B 2 138 ? 191.407 196.641 115.295 1.00 56.58  ? 156  ARG C NH2 1 
ATOM   6860  N N   . LEU B 2 139 ? 188.734 196.374 110.342 1.00 40.29  ? 157  LEU C N   1 
ATOM   6861  C CA  . LEU B 2 139 ? 188.977 197.779 110.133 1.00 40.29  ? 157  LEU C CA  1 
ATOM   6862  C C   . LEU B 2 139 ? 187.845 198.387 109.356 1.00 40.29  ? 157  LEU C C   1 
ATOM   6863  O O   . LEU B 2 139 ? 187.723 199.607 109.266 1.00 40.29  ? 157  LEU C O   1 
ATOM   6864  C CB  . LEU B 2 139 ? 190.259 197.979 109.333 1.00 57.27  ? 157  LEU C CB  1 
ATOM   6865  C CG  . LEU B 2 139 ? 191.563 197.491 109.959 1.00 57.27  ? 157  LEU C CG  1 
ATOM   6866  C CD1 . LEU B 2 139 ? 192.672 197.689 108.932 1.00 57.27  ? 157  LEU C CD1 1 
ATOM   6867  C CD2 . LEU B 2 139 ? 191.881 198.219 111.260 1.00 57.27  ? 157  LEU C CD2 1 
ATOM   6868  N N   . PHE B 2 140 ? 187.030 197.539 108.755 1.00 40.29  ? 158  PHE C N   1 
ATOM   6869  C CA  . PHE B 2 140 ? 185.937 197.995 107.948 1.00 40.29  ? 158  PHE C CA  1 
ATOM   6870  C C   . PHE B 2 140 ? 184.658 197.585 108.592 1.00 40.29  ? 158  PHE C C   1 
ATOM   6871  O O   . PHE B 2 140 ? 183.614 197.609 107.952 1.00 40.29  ? 158  PHE C O   1 
ATOM   6872  C CB  . PHE B 2 140 ? 186.060 197.381 106.592 1.00 54.49  ? 158  PHE C CB  1 
ATOM   6873  C CG  . PHE B 2 140 ? 187.356 197.678 106.087 1.00 54.49  ? 158  PHE C CG  1 
ATOM   6874  C CD1 . PHE B 2 140 ? 187.689 198.924 105.650 1.00 54.49  ? 158  PHE C CD1 1 
ATOM   6875  C CD2 . PHE B 2 140 ? 188.303 196.703 106.108 1.00 54.49  ? 158  PHE C CD2 1 
ATOM   6876  C CE1 . PHE B 2 140 ? 188.960 199.174 105.235 1.00 54.49  ? 158  PHE C CE1 1 
ATOM   6877  C CE2 . PHE B 2 140 ? 189.567 196.947 105.692 1.00 54.49  ? 158  PHE C CE2 1 
ATOM   6878  C CZ  . PHE B 2 140 ? 189.894 198.167 105.261 1.00 54.49  ? 158  PHE C CZ  1 
ATOM   6879  N N   . GLN B 2 141 ? 184.746 197.220 109.865 1.00 40.29  ? 159  GLN C N   1 
ATOM   6880  C CA  . GLN B 2 141 ? 183.634 196.741 110.647 1.00 40.29  ? 159  GLN C CA  1 
ATOM   6881  C C   . GLN B 2 141 ? 182.994 195.489 110.063 1.00 40.29  ? 159  GLN C C   1 
ATOM   6882  O O   . GLN B 2 141 ? 181.776 195.300 110.131 1.00 40.29  ? 159  GLN C O   1 
ATOM   6883  C CB  . GLN B 2 141 ? 182.587 197.856 110.755 1.00 54.76  ? 159  GLN C CB  1 
ATOM   6884  C CG  . GLN B 2 141 ? 183.080 199.073 111.438 1.00 54.76  ? 159  GLN C CG  1 
ATOM   6885  C CD  . GLN B 2 141 ? 183.307 198.816 112.874 1.00 54.76  ? 159  GLN C CD  1 
ATOM   6886  O OE1 . GLN B 2 141 ? 182.350 198.554 113.621 1.00 54.76  ? 159  GLN C OE1 1 
ATOM   6887  N NE2 . GLN B 2 141 ? 184.560 198.866 113.291 1.00 54.76  ? 159  GLN C NE2 1 
ATOM   6888  N N   . ILE B 2 142 ? 183.816 194.588 109.544 1.00 40.29  ? 160  ILE C N   1 
ATOM   6889  C CA  . ILE B 2 142 ? 183.325 193.353 108.981 1.00 40.29  ? 160  ILE C CA  1 
ATOM   6890  C C   . ILE B 2 142 ? 183.657 192.190 109.918 1.00 40.29  ? 160  ILE C C   1 
ATOM   6891  O O   . ILE B 2 142 ? 184.832 191.992 110.212 1.00 40.29  ? 160  ILE C O   1 
ATOM   6892  C CB  . ILE B 2 142 ? 183.981 193.098 107.614 1.00 57.27  ? 160  ILE C CB  1 
ATOM   6893  C CG1 . ILE B 2 142 ? 183.657 194.241 106.658 1.00 57.27  ? 160  ILE C CG1 1 
ATOM   6894  C CG2 . ILE B 2 142 ? 183.518 191.751 107.071 1.00 57.27  ? 160  ILE C CG2 1 
ATOM   6895  C CD1 . ILE B 2 142 ? 184.487 194.248 105.377 1.00 57.27  ? 160  ILE C CD1 1 
ATOM   6896  N N   . PRO B 2 143 ? 182.666 191.440 110.444 1.00 40.29  ? 161  PRO C N   1 
ATOM   6897  C CA  . PRO B 2 143 ? 182.862 190.311 111.332 1.00 40.29  ? 161  PRO C CA  1 
ATOM   6898  C C   . PRO B 2 143 ? 183.382 189.115 110.566 1.00 40.29  ? 161  PRO C C   1 
ATOM   6899  O O   . PRO B 2 143 ? 183.046 188.949 109.385 1.00 40.29  ? 161  PRO C O   1 
ATOM   6900  C CB  . PRO B 2 143 ? 181.461 190.054 111.883 1.00 68.85  ? 161  PRO C CB  1 
ATOM   6901  C CG  . PRO B 2 143 ? 180.543 190.510 110.785 1.00 68.85  ? 161  PRO C CG  1 
ATOM   6902  C CD  . PRO B 2 143 ? 181.256 191.701 110.125 1.00 68.85  ? 161  PRO C CD  1 
ATOM   6903  N N   . GLN B 2 144 ? 184.103 188.251 111.264 1.00 40.29  ? 162  GLN C N   1 
ATOM   6904  C CA  . GLN B 2 144 ? 184.596 187.015 110.679 1.00 40.29  ? 162  GLN C CA  1 
ATOM   6905  C C   . GLN B 2 144 ? 184.353 185.798 111.552 1.00 40.29  ? 162  GLN C C   1 
ATOM   6906  O O   . GLN B 2 144 ? 184.643 185.817 112.746 1.00 40.29  ? 162  GLN C O   1 
ATOM   6907  C CB  . GLN B 2 144 ? 186.090 187.123 110.472 1.00 54.76  ? 162  GLN C CB  1 
ATOM   6908  C CG  . GLN B 2 144 ? 186.732 185.927 109.807 1.00 54.76  ? 162  GLN C CG  1 
ATOM   6909  C CD  . GLN B 2 144 ? 188.173 186.115 109.739 1.00 54.76  ? 162  GLN C CD  1 
ATOM   6910  O OE1 . GLN B 2 144 ? 188.636 187.217 109.986 1.00 54.76  ? 162  GLN C OE1 1 
ATOM   6911  N NE2 . GLN B 2 144 ? 188.922 185.068 109.448 1.00 54.76  ? 162  GLN C NE2 1 
ATOM   6912  N N   . ILE B 2 145 ? 183.885 184.724 110.957 1.00 40.29  ? 163  ILE C N   1 
ATOM   6913  C CA  . ILE B 2 145 ? 183.745 183.495 111.711 1.00 40.29  ? 163  ILE C CA  1 
ATOM   6914  C C   . ILE B 2 145 ? 184.712 182.477 111.136 1.00 40.29  ? 163  ILE C C   1 
ATOM   6915  O O   . ILE B 2 145 ? 184.770 182.329 109.909 1.00 40.29  ? 163  ILE C O   1 
ATOM   6916  C CB  . ILE B 2 145 ? 182.285 182.997 111.687 1.00 57.27  ? 163  ILE C CB  1 
ATOM   6917  C CG1 . ILE B 2 145 ? 182.124 181.770 112.573 1.00 57.27  ? 163  ILE C CG1 1 
ATOM   6918  C CG2 . ILE B 2 145 ? 181.879 182.633 110.270 1.00 57.27  ? 163  ILE C CG2 1 
ATOM   6919  C CD1 . ILE B 2 145 ? 180.686 181.429 112.932 1.00 57.27  ? 163  ILE C CD1 1 
ATOM   6920  N N   . SER B 2 146 ? 185.498 181.809 111.981 1.00 40.29  ? 164  SER C N   1 
ATOM   6921  C CA  . SER B 2 146 ? 186.376 180.794 111.430 1.00 40.29  ? 164  SER C CA  1 
ATOM   6922  C C   . SER B 2 146 ? 185.509 179.590 111.249 1.00 40.29  ? 164  SER C C   1 
ATOM   6923  O O   . SER B 2 146 ? 184.488 179.446 111.931 1.00 40.29  ? 164  SER C O   1 
ATOM   6924  C CB  . SER B 2 146 ? 187.540 180.411 112.325 1.00 53.66  ? 164  SER C CB  1 
ATOM   6925  O OG  . SER B 2 146 ? 187.117 179.673 113.434 1.00 53.66  ? 164  SER C OG  1 
ATOM   6926  N N   . TYR B 2 147 ? 185.917 178.664 110.404 1.00 40.29  ? 165  TYR C N   1 
ATOM   6927  C CA  . TYR B 2 147 ? 185.122 177.454 110.294 1.00 40.29  ? 165  TYR C CA  1 
ATOM   6928  C C   . TYR B 2 147 ? 185.975 176.311 110.711 1.00 40.29  ? 165  TYR C C   1 
ATOM   6929  O O   . TYR B 2 147 ? 185.482 175.257 111.087 1.00 40.29  ? 165  TYR C O   1 
ATOM   6930  C CB  . TYR B 2 147 ? 184.587 177.252 108.888 1.00 54.08  ? 165  TYR C CB  1 
ATOM   6931  C CG  . TYR B 2 147 ? 185.639 177.040 107.896 1.00 54.08  ? 165  TYR C CG  1 
ATOM   6932  C CD1 . TYR B 2 147 ? 186.118 175.786 107.652 1.00 54.08  ? 165  TYR C CD1 1 
ATOM   6933  C CD2 . TYR B 2 147 ? 186.157 178.102 107.239 1.00 54.08  ? 165  TYR C CD2 1 
ATOM   6934  C CE1 . TYR B 2 147 ? 187.132 175.613 106.753 1.00 54.08  ? 165  TYR C CE1 1 
ATOM   6935  C CE2 . TYR B 2 147 ? 187.164 177.909 106.349 1.00 54.08  ? 165  TYR C CE2 1 
ATOM   6936  C CZ  . TYR B 2 147 ? 187.648 176.690 106.114 1.00 54.08  ? 165  TYR C CZ  1 
ATOM   6937  O OH  . TYR B 2 147 ? 188.674 176.557 105.228 1.00 54.08  ? 165  TYR C OH  1 
ATOM   6938  N N   . ALA B 2 148 ? 187.278 176.504 110.635 1.00 40.29  ? 166  ALA C N   1 
ATOM   6939  C CA  . ALA B 2 148 ? 188.172 175.441 110.978 1.00 40.29  ? 166  ALA C CA  1 
ATOM   6940  C C   . ALA B 2 148 ? 189.294 175.915 111.873 1.00 40.29  ? 166  ALA C C   1 
ATOM   6941  O O   . ALA B 2 148 ? 189.815 175.095 112.646 1.00 40.29  ? 166  ALA C O   1 
ATOM   6942  C CB  . ALA B 2 148 ? 188.688 174.793 109.718 1.00 54.43  ? 166  ALA C CB  1 
ATOM   6943  N N   . SER B 2 149 ? 189.695 177.192 111.767 1.00 40.29  ? 167  SER C N   1 
ATOM   6944  C CA  . SER B 2 149 ? 190.795 177.680 112.602 1.00 40.29  ? 167  SER C CA  1 
ATOM   6945  C C   . SER B 2 149 ? 190.388 177.748 114.057 1.00 40.29  ? 167  SER C C   1 
ATOM   6946  O O   . SER B 2 149 ? 189.326 178.290 114.411 1.00 40.29  ? 167  SER C O   1 
ATOM   6947  C CB  . SER B 2 149 ? 191.303 179.043 112.197 1.00 53.66  ? 167  SER C CB  1 
ATOM   6948  O OG  . SER B 2 149 ? 192.266 179.510 113.137 1.00 53.66  ? 167  SER C OG  1 
ATOM   6949  N N   . THR B 2 150 ? 191.185 177.161 114.936 1.00 40.29  ? 168  THR C N   1 
ATOM   6950  C CA  . THR B 2 150 ? 190.829 177.144 116.356 1.00 40.29  ? 168  THR C CA  1 
ATOM   6951  C C   . THR B 2 150 ? 191.533 178.225 117.148 1.00 40.29  ? 168  THR C C   1 
ATOM   6952  O O   . THR B 2 150 ? 190.960 178.710 118.107 1.00 40.29  ? 168  THR C O   1 
ATOM   6953  C CB  . THR B 2 150 ? 191.134 175.789 116.986 1.00 55.15  ? 168  THR C CB  1 
ATOM   6954  O OG1 . THR B 2 150 ? 192.517 175.647 117.202 1.00 55.15  ? 168  THR C OG1 1 
ATOM   6955  C CG2 . THR B 2 150 ? 190.695 174.617 116.120 1.00 55.15  ? 168  THR C CG2 1 
ATOM   6956  N N   . SER B 2 151 ? 192.756 178.584 116.748 1.00 40.29  ? 169  SER C N   1 
ATOM   6957  C CA  . SER B 2 151 ? 193.792 179.100 117.643 1.00 40.29  ? 169  SER C CA  1 
ATOM   6958  C C   . SER B 2 151 ? 193.333 180.043 118.744 1.00 40.29  ? 169  SER C C   1 
ATOM   6959  O O   . SER B 2 151 ? 192.666 181.052 118.521 1.00 40.29  ? 169  SER C O   1 
ATOM   6960  C CB  . SER B 2 151 ? 194.917 179.773 116.868 1.00 53.66  ? 169  SER C CB  1 
ATOM   6961  O OG  . SER B 2 151 ? 195.939 180.159 117.772 1.00 53.66  ? 169  SER C OG  1 
ATOM   6962  N N   . ALA B 2 152 ? 193.820 179.760 119.946 1.00 40.29  ? 170  ALA C N   1 
ATOM   6963  C CA  . ALA B 2 152 ? 193.568 180.559 121.127 1.00 40.29  ? 170  ALA C CA  1 
ATOM   6964  C C   . ALA B 2 152 ? 194.028 182.001 120.983 1.00 40.29  ? 170  ALA C C   1 
ATOM   6965  O O   . ALA B 2 152 ? 193.551 182.834 121.749 1.00 40.29  ? 170  ALA C O   1 
ATOM   6966  C CB  . ALA B 2 152 ? 194.266 179.895 122.310 1.00 54.43  ? 170  ALA C CB  1 
ATOM   6967  N N   . LYS B 2 153 ? 194.891 182.355 120.015 1.00 40.29  ? 171  LYS C N   1 
ATOM   6968  C CA  . LYS B 2 153 ? 195.298 183.740 119.948 1.00 40.29  ? 171  LYS C CA  1 
ATOM   6969  C C   . LYS B 2 153 ? 194.094 184.556 119.547 1.00 40.29  ? 171  LYS C C   1 
ATOM   6970  O O   . LYS B 2 153 ? 193.943 185.728 119.926 1.00 40.29  ? 171  LYS C O   1 
ATOM   6971  C CB  . LYS B 2 153 ? 196.409 183.927 118.935 1.00 54.27  ? 171  LYS C CB  1 
ATOM   6972  C CG  . LYS B 2 153 ? 197.688 183.252 119.332 1.00 54.27  ? 171  LYS C CG  1 
ATOM   6973  C CD  . LYS B 2 153 ? 198.813 183.550 118.361 1.00 54.27  ? 171  LYS C CD  1 
ATOM   6974  C CE  . LYS B 2 153 ? 200.060 182.729 118.700 1.00 54.27  ? 171  LYS C CE  1 
ATOM   6975  N NZ  . LYS B 2 153 ? 199.912 181.294 118.250 1.00 54.27  ? 171  LYS C NZ  1 
ATOM   6976  N N   . LEU B 2 154 ? 193.189 183.933 118.802 1.00 40.29  ? 172  LEU C N   1 
ATOM   6977  C CA  . LEU B 2 154 ? 192.023 184.609 118.331 1.00 40.29  ? 172  LEU C CA  1 
ATOM   6978  C C   . LEU B 2 154 ? 190.979 184.488 119.422 1.00 40.29  ? 172  LEU C C   1 
ATOM   6979  O O   . LEU B 2 154 ? 190.002 183.758 119.326 1.00 40.29  ? 172  LEU C O   1 
ATOM   6980  C CB  . LEU B 2 154 ? 191.578 183.976 117.003 1.00 57.27  ? 172  LEU C CB  1 
ATOM   6981  C CG  . LEU B 2 154 ? 190.489 184.683 116.186 1.00 57.27  ? 172  LEU C CG  1 
ATOM   6982  C CD1 . LEU B 2 154 ? 190.909 186.082 115.784 1.00 57.27  ? 172  LEU C CD1 1 
ATOM   6983  C CD2 . LEU B 2 154 ? 190.181 183.871 114.947 1.00 57.27  ? 172  LEU C CD2 1 
ATOM   6984  N N   . SER B 2 155 ? 191.350 184.940 120.599 1.00 40.29  ? 173  SER C N   1 
ATOM   6985  C CA  . SER B 2 155 ? 190.507 185.212 121.745 1.00 40.29  ? 173  SER C CA  1 
ATOM   6986  C C   . SER B 2 155 ? 190.690 186.678 122.127 1.00 40.29  ? 173  SER C C   1 
ATOM   6987  O O   . SER B 2 155 ? 189.891 187.231 122.880 1.00 40.29  ? 173  SER C O   1 
ATOM   6988  C CB  . SER B 2 155 ? 190.920 184.316 122.907 1.00 53.66  ? 173  SER C CB  1 
ATOM   6989  O OG  . SER B 2 155 ? 192.271 184.535 123.250 1.00 53.66  ? 173  SER C OG  1 
ATOM   6990  N N   . ASP B 2 156 ? 191.750 187.316 121.609 1.00 40.29  ? 174  ASP C N   1 
ATOM   6991  C CA  . ASP B 2 156 ? 192.115 188.647 122.036 1.00 40.29  ? 174  ASP C CA  1 
ATOM   6992  C C   . ASP B 2 156 ? 191.344 189.722 121.311 1.00 40.29  ? 174  ASP C C   1 
ATOM   6993  O O   . ASP B 2 156 ? 191.791 190.263 120.291 1.00 40.29  ? 174  ASP C O   1 
ATOM   6994  C CB  . ASP B 2 156 ? 193.601 188.878 121.814 1.00 51.30  ? 174  ASP C CB  1 
ATOM   6995  C CG  . ASP B 2 156 ? 194.065 190.220 122.316 1.00 51.30  ? 174  ASP C CG  1 
ATOM   6996  O OD1 . ASP B 2 156 ? 193.233 191.011 122.778 1.00 51.30  ? 174  ASP C OD1 1 
ATOM   6997  O OD2 . ASP B 2 156 ? 195.243 190.483 122.213 1.00 51.30  ? 174  ASP C OD2 1 
ATOM   6998  N N   . LYS B 2 157 ? 190.236 190.120 121.904 1.00 40.29  ? 175  LYS C N   1 
ATOM   6999  C CA  . LYS B 2 157 ? 189.368 191.080 121.259 1.00 40.29  ? 175  LYS C CA  1 
ATOM   7000  C C   . LYS B 2 157 ? 189.932 192.489 121.212 1.00 40.29  ? 175  LYS C C   1 
ATOM   7001  O O   . LYS B 2 157 ? 189.301 193.385 120.661 1.00 40.29  ? 175  LYS C O   1 
ATOM   7002  C CB  . LYS B 2 157 ? 187.977 191.096 121.862 1.00 57.63  ? 175  LYS C CB  1 
ATOM   7003  C CG  . LYS B 2 157 ? 187.192 189.826 121.586 1.00 57.63  ? 175  LYS C CG  1 
ATOM   7004  C CD  . LYS B 2 157 ? 185.711 190.020 121.813 1.00 57.63  ? 175  LYS C CD  1 
ATOM   7005  C CE  . LYS B 2 157 ? 185.382 190.315 123.256 1.00 57.63  ? 175  LYS C CE  1 
ATOM   7006  N NZ  . LYS B 2 157 ? 183.930 190.364 123.478 1.00 57.63  ? 175  LYS C NZ  1 
ATOM   7007  N N   . SER B 2 158 ? 191.088 192.731 121.835 1.00 40.29  ? 176  SER C N   1 
ATOM   7008  C CA  . SER B 2 158 ? 191.658 194.067 121.753 1.00 40.29  ? 176  SER C CA  1 
ATOM   7009  C C   . SER B 2 158 ? 192.341 194.229 120.402 1.00 40.29  ? 176  SER C C   1 
ATOM   7010  O O   . SER B 2 158 ? 192.703 195.336 119.992 1.00 40.29  ? 176  SER C O   1 
ATOM   7011  C CB  . SER B 2 158 ? 192.666 194.327 122.843 1.00 53.66  ? 176  SER C CB  1 
ATOM   7012  O OG  . SER B 2 158 ? 193.853 193.633 122.610 1.00 53.66  ? 176  SER C OG  1 
ATOM   7013  N N   . ARG B 2 159 ? 192.570 193.109 119.724 1.00 40.29  ? 177  ARG C N   1 
ATOM   7014  C CA  . ARG B 2 159 ? 193.221 193.096 118.439 1.00 40.29  ? 177  ARG C CA  1 
ATOM   7015  C C   . ARG B 2 159 ? 192.294 192.548 117.379 1.00 40.29  ? 177  ARG C C   1 
ATOM   7016  O O   . ARG B 2 159 ? 192.358 192.943 116.215 1.00 40.29  ? 177  ARG C O   1 
ATOM   7017  C CB  . ARG B 2 159 ? 194.484 192.266 118.504 1.00 56.58  ? 177  ARG C CB  1 
ATOM   7018  C CG  . ARG B 2 159 ? 195.602 192.881 119.314 1.00 56.58  ? 177  ARG C CG  1 
ATOM   7019  C CD  . ARG B 2 159 ? 196.775 191.988 119.401 1.00 56.58  ? 177  ARG C CD  1 
ATOM   7020  N NE  . ARG B 2 159 ? 197.926 192.654 120.032 1.00 56.58  ? 177  ARG C NE  1 
ATOM   7021  C CZ  . ARG B 2 159 ? 198.172 192.749 121.367 1.00 56.58  ? 177  ARG C CZ  1 
ATOM   7022  N NH1 . ARG B 2 159 ? 199.255 193.382 121.793 1.00 56.58  ? 177  ARG C NH1 1 
ATOM   7023  N NH2 . ARG B 2 159 ? 197.361 192.221 122.270 1.00 56.58  ? 177  ARG C NH2 1 
ATOM   7024  N N   . TYR B 2 160 ? 191.433 191.635 117.789 1.00 40.29  ? 178  TYR C N   1 
ATOM   7025  C CA  . TYR B 2 160 ? 190.539 190.956 116.889 1.00 40.29  ? 178  TYR C CA  1 
ATOM   7026  C C   . TYR B 2 160 ? 189.160 191.040 117.456 1.00 40.29  ? 178  TYR C C   1 
ATOM   7027  O O   . TYR B 2 160 ? 188.717 190.116 118.097 1.00 40.29  ? 178  TYR C O   1 
ATOM   7028  C CB  . TYR B 2 160 ? 190.910 189.501 116.799 1.00 54.08  ? 178  TYR C CB  1 
ATOM   7029  C CG  . TYR B 2 160 ? 192.320 189.314 116.557 1.00 54.08  ? 178  TYR C CG  1 
ATOM   7030  C CD1 . TYR B 2 160 ? 192.878 189.559 115.343 1.00 54.08  ? 178  TYR C CD1 1 
ATOM   7031  C CD2 . TYR B 2 160 ? 193.090 188.907 117.610 1.00 54.08  ? 178  TYR C CD2 1 
ATOM   7032  C CE1 . TYR B 2 160 ? 194.218 189.389 115.195 1.00 54.08  ? 178  TYR C CE1 1 
ATOM   7033  C CE2 . TYR B 2 160 ? 194.415 188.737 117.467 1.00 54.08  ? 178  TYR C CE2 1 
ATOM   7034  C CZ  . TYR B 2 160 ? 194.988 188.980 116.261 1.00 54.08  ? 178  TYR C CZ  1 
ATOM   7035  O OH  . TYR B 2 160 ? 196.344 188.808 116.122 1.00 54.08  ? 178  TYR C OH  1 
ATOM   7036  N N   . ASP B 2 161 ? 188.471 192.124 117.315 1.00 40.29  ? 179  ASP C N   1 
ATOM   7037  C CA  . ASP B 2 161 ? 187.239 192.201 118.061 1.00 40.29  ? 179  ASP C CA  1 
ATOM   7038  C C   . ASP B 2 161 ? 186.088 191.425 117.479 1.00 40.29  ? 179  ASP C C   1 
ATOM   7039  O O   . ASP B 2 161 ? 185.478 190.591 118.147 1.00 40.29  ? 179  ASP C O   1 
ATOM   7040  C CB  . ASP B 2 161 ? 186.887 193.666 118.242 1.00 51.30  ? 179  ASP C CB  1 
ATOM   7041  C CG  . ASP B 2 161 ? 186.921 194.437 116.942 1.00 51.30  ? 179  ASP C CG  1 
ATOM   7042  O OD1 . ASP B 2 161 ? 187.161 193.843 115.899 1.00 51.30  ? 179  ASP C OD1 1 
ATOM   7043  O OD2 . ASP B 2 161 ? 186.834 195.631 116.987 1.00 51.30  ? 179  ASP C OD2 1 
ATOM   7044  N N   . TYR B 2 162 ? 185.800 191.647 116.232 1.00 40.29  ? 180  TYR C N   1 
ATOM   7045  C CA  . TYR B 2 162 ? 184.617 191.040 115.684 1.00 40.29  ? 180  TYR C CA  1 
ATOM   7046  C C   . TYR B 2 162 ? 184.803 189.657 115.132 1.00 40.29  ? 180  TYR C C   1 
ATOM   7047  O O   . TYR B 2 162 ? 184.789 189.482 113.909 1.00 40.29  ? 180  TYR C O   1 
ATOM   7048  C CB  . TYR B 2 162 ? 184.039 191.906 114.584 1.00 54.08  ? 180  TYR C CB  1 
ATOM   7049  C CG  . TYR B 2 162 ? 183.643 193.272 114.975 1.00 54.08  ? 180  TYR C CG  1 
ATOM   7050  C CD1 . TYR B 2 162 ? 183.438 193.644 116.298 1.00 54.08  ? 180  TYR C CD1 1 
ATOM   7051  C CD2 . TYR B 2 162 ? 183.508 194.196 113.979 1.00 54.08  ? 180  TYR C CD2 1 
ATOM   7052  C CE1 . TYR B 2 162 ? 183.108 194.926 116.588 1.00 54.08  ? 180  TYR C CE1 1 
ATOM   7053  C CE2 . TYR B 2 162 ? 183.179 195.465 114.289 1.00 54.08  ? 180  TYR C CE2 1 
ATOM   7054  C CZ  . TYR B 2 162 ? 182.981 195.839 115.585 1.00 54.08  ? 180  TYR C CZ  1 
ATOM   7055  O OH  . TYR B 2 162 ? 182.652 197.146 115.875 1.00 54.08  ? 180  TYR C OH  1 
ATOM   7056  N N   . PHE B 2 163 ? 184.956 188.668 115.990 1.00 40.29  ? 181  PHE C N   1 
ATOM   7057  C CA  . PHE B 2 163 ? 185.110 187.329 115.435 1.00 40.29  ? 181  PHE C CA  1 
ATOM   7058  C C   . PHE B 2 163 ? 184.483 186.226 116.265 1.00 40.29  ? 181  PHE C C   1 
ATOM   7059  O O   . PHE B 2 163 ? 184.269 186.313 117.486 1.00 40.29  ? 181  PHE C O   1 
ATOM   7060  C CB  . PHE B 2 163 ? 186.567 186.898 115.287 1.00 54.49  ? 181  PHE C CB  1 
ATOM   7061  C CG  . PHE B 2 163 ? 187.098 186.616 116.573 1.00 54.49  ? 181  PHE C CG  1 
ATOM   7062  C CD1 . PHE B 2 163 ? 187.531 187.598 117.335 1.00 54.49  ? 181  PHE C CD1 1 
ATOM   7063  C CD2 . PHE B 2 163 ? 187.089 185.321 117.074 1.00 54.49  ? 181  PHE C CD2 1 
ATOM   7064  C CE1 . PHE B 2 163 ? 187.964 187.347 118.601 1.00 54.49  ? 181  PHE C CE1 1 
ATOM   7065  C CE2 . PHE B 2 163 ? 187.498 185.081 118.324 1.00 54.49  ? 181  PHE C CE2 1 
ATOM   7066  C CZ  . PHE B 2 163 ? 187.936 186.102 119.085 1.00 54.49  ? 181  PHE C CZ  1 
ATOM   7067  N N   . ALA B 2 164 ? 184.285 185.115 115.589 1.00 40.29  ? 182  ALA C N   1 
ATOM   7068  C CA  . ALA B 2 164 ? 183.841 183.915 116.260 1.00 40.29  ? 182  ALA C CA  1 
ATOM   7069  C C   . ALA B 2 164 ? 184.610 182.719 115.739 1.00 40.29  ? 182  ALA C C   1 
ATOM   7070  O O   . ALA B 2 164 ? 185.064 182.707 114.596 1.00 40.29  ? 182  ALA C O   1 
ATOM   7071  C CB  . ALA B 2 164 ? 182.349 183.735 116.084 1.00 54.43  ? 182  ALA C CB  1 
ATOM   7072  N N   . ARG B 2 165 ? 184.883 181.745 116.609 1.00 40.29  ? 183  ARG C N   1 
ATOM   7073  C CA  . ARG B 2 165 ? 185.588 180.509 116.265 1.00 40.29  ? 183  ARG C CA  1 
ATOM   7074  C C   . ARG B 2 165 ? 184.589 179.379 116.293 1.00 40.29  ? 183  ARG C C   1 
ATOM   7075  O O   . ARG B 2 165 ? 184.125 179.014 117.366 1.00 40.29  ? 183  ARG C O   1 
ATOM   7076  C CB  . ARG B 2 165 ? 186.682 180.180 117.288 1.00 56.58  ? 183  ARG C CB  1 
ATOM   7077  C CG  . ARG B 2 165 ? 187.886 181.117 117.269 1.00 56.58  ? 183  ARG C CG  1 
ATOM   7078  C CD  . ARG B 2 165 ? 188.588 181.007 118.622 1.00 56.58  ? 183  ARG C CD  1 
ATOM   7079  N NE  . ARG B 2 165 ? 187.782 181.671 119.672 1.00 56.58  ? 183  ARG C NE  1 
ATOM   7080  C CZ  . ARG B 2 165 ? 188.114 181.845 120.932 1.00 56.58  ? 183  ARG C CZ  1 
ATOM   7081  N NH1 . ARG B 2 165 ? 187.438 182.649 121.695 1.00 56.58  ? 183  ARG C NH1 1 
ATOM   7082  N NH2 . ARG B 2 165 ? 189.127 181.229 121.456 1.00 56.58  ? 183  ARG C NH2 1 
ATOM   7083  N N   . THR B 2 166 ? 184.296 178.763 115.153 1.00 40.29  ? 184  THR C N   1 
ATOM   7084  C CA  . THR B 2 166 ? 183.340 177.638 115.159 1.00 40.29  ? 184  THR C CA  1 
ATOM   7085  C C   . THR B 2 166 ? 183.848 176.459 116.001 1.00 40.29  ? 184  THR C C   1 
ATOM   7086  O O   . THR B 2 166 ? 183.060 175.659 116.495 1.00 40.29  ? 184  THR C O   1 
ATOM   7087  C CB  . THR B 2 166 ? 182.976 177.210 113.733 1.00 55.15  ? 184  THR C CB  1 
ATOM   7088  O OG1 . THR B 2 166 ? 182.420 178.304 113.047 1.00 55.15  ? 184  THR C OG1 1 
ATOM   7089  C CG2 . THR B 2 166 ? 181.895 176.135 113.702 1.00 55.15  ? 184  THR C CG2 1 
ATOM   7090  N N   . VAL B 2 167 ? 185.161 176.370 116.208 1.00 40.29  ? 185  VAL C N   1 
ATOM   7091  C CA  . VAL B 2 167 ? 185.805 175.297 116.958 1.00 40.29  ? 185  VAL C CA  1 
ATOM   7092  C C   . VAL B 2 167 ? 186.629 175.879 118.104 1.00 40.29  ? 185  VAL C C   1 
ATOM   7093  O O   . VAL B 2 167 ? 187.465 176.748 117.852 1.00 40.29  ? 185  VAL C O   1 
ATOM   7094  C CB  . VAL B 2 167 ? 186.692 174.479 116.021 1.00 56.74  ? 185  VAL C CB  1 
ATOM   7095  C CG1 . VAL B 2 167 ? 187.288 173.279 116.753 1.00 56.74  ? 185  VAL C CG1 1 
ATOM   7096  C CG2 . VAL B 2 167 ? 185.894 173.966 114.825 1.00 56.74  ? 185  VAL C CG2 1 
ATOM   7097  N N   . PRO B 2 168 ? 186.453 175.408 119.344 1.00 40.29  ? 186  PRO C N   1 
ATOM   7098  C CA  . PRO B 2 168 ? 187.189 175.933 120.479 1.00 40.29  ? 186  PRO C CA  1 
ATOM   7099  C C   . PRO B 2 168 ? 188.637 175.429 120.463 1.00 40.29  ? 186  PRO C C   1 
ATOM   7100  O O   . PRO B 2 168 ? 188.871 174.242 120.239 1.00 40.29  ? 186  PRO C O   1 
ATOM   7101  C CB  . PRO B 2 168 ? 186.426 175.458 121.710 1.00 68.85  ? 186  PRO C CB  1 
ATOM   7102  C CG  . PRO B 2 168 ? 185.770 174.162 121.248 1.00 68.85  ? 186  PRO C CG  1 
ATOM   7103  C CD  . PRO B 2 168 ? 185.544 174.356 119.752 1.00 68.85  ? 186  PRO C CD  1 
ATOM   7104  N N   . PRO B 2 169 ? 189.637 176.287 120.681 1.00 40.29  ? 187  PRO C N   1 
ATOM   7105  C CA  . PRO B 2 169 ? 191.027 175.876 120.675 1.00 40.29  ? 187  PRO C CA  1 
ATOM   7106  C C   . PRO B 2 169 ? 191.341 174.877 121.767 1.00 40.29  ? 187  PRO C C   1 
ATOM   7107  O O   . PRO B 2 169 ? 190.691 174.815 122.799 1.00 40.29  ? 187  PRO C O   1 
ATOM   7108  C CB  . PRO B 2 169 ? 191.868 177.142 120.766 1.00 68.85  ? 187  PRO C CB  1 
ATOM   7109  C CG  . PRO B 2 169 ? 190.881 178.268 121.080 1.00 68.85  ? 187  PRO C CG  1 
ATOM   7110  C CD  . PRO B 2 169 ? 189.502 177.720 120.754 1.00 68.85  ? 187  PRO C CD  1 
ATOM   7111  N N   . ASP B 2 170 ? 192.397 174.112 121.546 1.00 40.29  ? 188  ASP C N   1 
ATOM   7112  C CA  . ASP B 2 170 ? 192.733 172.974 122.395 1.00 40.29  ? 188  ASP C CA  1 
ATOM   7113  C C   . ASP B 2 170 ? 192.967 173.339 123.863 1.00 40.29  ? 188  ASP C C   1 
ATOM   7114  O O   . ASP B 2 170 ? 192.818 172.471 124.720 1.00 40.29  ? 188  ASP C O   1 
ATOM   7115  C CB  . ASP B 2 170 ? 193.900 172.182 121.791 1.00 51.30  ? 188  ASP C CB  1 
ATOM   7116  C CG  . ASP B 2 170 ? 195.224 172.931 121.643 1.00 51.30  ? 188  ASP C CG  1 
ATOM   7117  O OD1 . ASP B 2 170 ? 195.290 174.141 121.948 1.00 51.30  ? 188  ASP C OD1 1 
ATOM   7118  O OD2 . ASP B 2 170 ? 196.177 172.279 121.152 1.00 51.30  ? 188  ASP C OD2 1 
ATOM   7119  N N   . PHE B 2 171 ? 193.184 174.620 124.180 1.00 40.29  ? 189  PHE C N   1 
ATOM   7120  C CA  . PHE B 2 171 ? 193.110 175.134 125.544 1.00 40.29  ? 189  PHE C CA  1 
ATOM   7121  C C   . PHE B 2 171 ? 191.912 174.545 126.312 1.00 40.29  ? 189  PHE C C   1 
ATOM   7122  O O   . PHE B 2 171 ? 192.062 174.193 127.476 1.00 40.29  ? 189  PHE C O   1 
ATOM   7123  C CB  . PHE B 2 171 ? 193.028 176.673 125.524 1.00 54.49  ? 189  PHE C CB  1 
ATOM   7124  C CG  . PHE B 2 171 ? 191.601 177.162 125.577 1.00 54.49  ? 189  PHE C CG  1 
ATOM   7125  C CD1 . PHE B 2 171 ? 190.850 177.152 124.404 1.00 54.49  ? 189  PHE C CD1 1 
ATOM   7126  C CD2 . PHE B 2 171 ? 190.960 177.361 126.811 1.00 54.49  ? 189  PHE C CD2 1 
ATOM   7127  C CE1 . PHE B 2 171 ? 189.454 177.272 124.446 1.00 54.49  ? 189  PHE C CE1 1 
ATOM   7128  C CE2 . PHE B 2 171 ? 189.567 177.516 126.858 1.00 54.49  ? 189  PHE C CE2 1 
ATOM   7129  C CZ  . PHE B 2 171 ? 188.811 177.454 125.678 1.00 54.49  ? 189  PHE C CZ  1 
ATOM   7130  N N   . PHE B 2 172 ? 190.730 174.404 125.689 1.00 40.29  ? 190  PHE C N   1 
ATOM   7131  C CA  . PHE B 2 172 ? 189.531 174.026 126.431 1.00 40.29  ? 190  PHE C CA  1 
ATOM   7132  C C   . PHE B 2 172 ? 189.702 172.653 127.066 1.00 40.29  ? 190  PHE C C   1 
ATOM   7133  O O   . PHE B 2 172 ? 189.086 172.352 128.083 1.00 40.29  ? 190  PHE C O   1 
ATOM   7134  C CB  . PHE B 2 172 ? 188.292 174.025 125.523 1.00 54.49  ? 190  PHE C CB  1 
ATOM   7135  C CG  . PHE B 2 172 ? 188.106 172.741 124.742 1.00 54.49  ? 190  PHE C CG  1 
ATOM   7136  C CD1 . PHE B 2 172 ? 187.565 171.597 125.357 1.00 54.49  ? 190  PHE C CD1 1 
ATOM   7137  C CD2 . PHE B 2 172 ? 188.517 172.665 123.406 1.00 54.49  ? 190  PHE C CD2 1 
ATOM   7138  C CE1 . PHE B 2 172 ? 187.544 170.369 124.677 1.00 54.49  ? 190  PHE C CE1 1 
ATOM   7139  C CE2 . PHE B 2 172 ? 188.497 171.442 122.718 1.00 54.49  ? 190  PHE C CE2 1 
ATOM   7140  C CZ  . PHE B 2 172 ? 188.039 170.287 123.365 1.00 54.49  ? 190  PHE C CZ  1 
ATOM   7141  N N   . GLN B 2 173 ? 190.528 171.801 126.464 1.00 40.29  ? 191  GLN C N   1 
ATOM   7142  C CA  . GLN B 2 173 ? 190.672 170.417 126.877 1.00 40.29  ? 191  GLN C CA  1 
ATOM   7143  C C   . GLN B 2 173 ? 191.153 170.337 128.315 1.00 40.29  ? 191  GLN C C   1 
ATOM   7144  O O   . GLN B 2 173 ? 190.750 169.434 129.038 1.00 40.29  ? 191  GLN C O   1 
ATOM   7145  C CB  . GLN B 2 173 ? 191.605 169.682 125.911 1.00 54.76  ? 191  GLN C CB  1 
ATOM   7146  C CG  . GLN B 2 173 ? 191.027 169.716 124.495 1.00 54.76  ? 191  GLN C CG  1 
ATOM   7147  C CD  . GLN B 2 173 ? 191.919 169.122 123.420 1.00 54.76  ? 191  GLN C CD  1 
ATOM   7148  O OE1 . GLN B 2 173 ? 192.752 168.258 123.640 1.00 54.76  ? 191  GLN C OE1 1 
ATOM   7149  N NE2 . GLN B 2 173 ? 191.729 169.540 122.195 1.00 54.76  ? 191  GLN C NE2 1 
ATOM   7150  N N   . ALA B 2 174 ? 191.893 171.347 128.767 1.00 40.29  ? 192  ALA C N   1 
ATOM   7151  C CA  . ALA B 2 174 ? 192.242 171.550 130.159 1.00 40.29  ? 192  ALA C CA  1 
ATOM   7152  C C   . ALA B 2 174 ? 191.101 171.227 131.119 1.00 40.29  ? 192  ALA C C   1 
ATOM   7153  O O   . ALA B 2 174 ? 191.304 170.553 132.121 1.00 40.29  ? 192  ALA C O   1 
ATOM   7154  C CB  . ALA B 2 174 ? 192.584 173.029 130.301 1.00 54.43  ? 192  ALA C CB  1 
ATOM   7155  N N   . LYS B 2 175 ? 189.898 171.690 130.787 1.00 40.29  ? 193  LYS C N   1 
ATOM   7156  C CA  . LYS B 2 175 ? 188.705 171.585 131.617 1.00 40.29  ? 193  LYS C CA  1 
ATOM   7157  C C   . LYS B 2 175 ? 188.360 170.120 131.807 1.00 40.29  ? 193  LYS C C   1 
ATOM   7158  O O   . LYS B 2 175 ? 188.343 169.604 132.917 1.00 40.29  ? 193  LYS C O   1 
ATOM   7159  C CB  . LYS B 2 175 ? 187.559 172.331 130.924 1.00 57.63  ? 193  LYS C CB  1 
ATOM   7160  C CG  . LYS B 2 175 ? 187.871 173.795 130.561 1.00 57.63  ? 193  LYS C CG  1 
ATOM   7161  C CD  . LYS B 2 175 ? 186.804 174.335 129.598 1.00 57.63  ? 193  LYS C CD  1 
ATOM   7162  C CE  . LYS B 2 175 ? 187.165 175.721 129.051 1.00 57.63  ? 193  LYS C CE  1 
ATOM   7163  N NZ  . LYS B 2 175 ? 186.068 176.277 128.215 1.00 57.63  ? 193  LYS C NZ  1 
ATOM   7164  N N   . ALA B 2 176 ? 188.207 169.426 130.694 1.00 40.29  ? 194  ALA C N   1 
ATOM   7165  C CA  . ALA B 2 176 ? 187.993 168.003 130.701 1.00 40.29  ? 194  ALA C CA  1 
ATOM   7166  C C   . ALA B 2 176 ? 189.129 167.268 131.391 1.00 40.29  ? 194  ALA C C   1 
ATOM   7167  O O   . ALA B 2 176 ? 188.885 166.399 132.214 1.00 40.29  ? 194  ALA C O   1 
ATOM   7168  C CB  . ALA B 2 176 ? 187.827 167.548 129.255 1.00 54.43  ? 194  ALA C CB  1 
ATOM   7169  N N   . MET B 2 177 ? 190.368 167.627 131.093 1.00 40.29  ? 195  MET C N   1 
ATOM   7170  C CA  . MET B 2 177 ? 191.537 166.958 131.629 1.00 40.29  ? 195  MET C CA  1 
ATOM   7171  C C   . MET B 2 177 ? 191.535 167.032 133.139 1.00 40.29  ? 195  MET C C   1 
ATOM   7172  O O   . MET B 2 177 ? 191.579 166.017 133.821 1.00 40.29  ? 195  MET C O   1 
ATOM   7173  C CB  . MET B 2 177 ? 192.782 167.623 131.059 1.00 56.05  ? 195  MET C CB  1 
ATOM   7174  C CG  . MET B 2 177 ? 192.932 167.294 129.579 1.00 56.05  ? 195  MET C CG  1 
ATOM   7175  S SD  . MET B 2 177 ? 193.800 168.573 128.654 1.00 56.05  ? 195  MET C SD  1 
ATOM   7176  C CE  . MET B 2 177 ? 194.211 167.617 127.174 1.00 56.05  ? 195  MET C CE  1 
ATOM   7177  N N   . ALA B 2 178 ? 191.391 168.232 133.666 1.00 40.29  ? 196  ALA C N   1 
ATOM   7178  C CA  . ALA B 2 178 ? 191.296 168.429 135.086 1.00 40.29  ? 196  ALA C CA  1 
ATOM   7179  C C   . ALA B 2 178 ? 190.115 167.636 135.659 1.00 40.29  ? 196  ALA C C   1 
ATOM   7180  O O   . ALA B 2 178 ? 190.230 166.976 136.686 1.00 40.29  ? 196  ALA C O   1 
ATOM   7181  C CB  . ALA B 2 178 ? 191.200 169.934 135.319 1.00 54.43  ? 196  ALA C CB  1 
ATOM   7182  N N   . GLU B 2 179 ? 188.983 167.615 134.971 1.00 40.29  ? 197  GLU C N   1 
ATOM   7183  C CA  . GLU B 2 179 ? 187.843 166.844 135.444 1.00 40.29  ? 197  GLU C CA  1 
ATOM   7184  C C   . GLU B 2 179 ? 188.073 165.346 135.416 1.00 40.29  ? 197  GLU C C   1 
ATOM   7185  O O   . GLU B 2 179 ? 187.606 164.653 136.318 1.00 40.29  ? 197  GLU C O   1 
ATOM   7186  C CB  . GLU B 2 179 ? 186.603 167.223 134.657 1.00 53.10  ? 197  GLU C CB  1 
ATOM   7187  C CG  . GLU B 2 179 ? 186.183 168.599 135.172 1.00 53.10  ? 197  GLU C CG  1 
ATOM   7188  C CD  . GLU B 2 179 ? 184.914 169.109 134.518 1.00 53.10  ? 197  GLU C CD  1 
ATOM   7189  O OE1 . GLU B 2 179 ? 184.225 168.310 133.853 1.00 53.10  ? 197  GLU C OE1 1 
ATOM   7190  O OE2 . GLU B 2 179 ? 184.602 170.300 134.745 1.00 53.10  ? 197  GLU C OE2 1 
ATOM   7191  N N   . ILE B 2 180 ? 188.840 164.831 134.466 1.00 40.29  ? 198  ILE C N   1 
ATOM   7192  C CA  . ILE B 2 180 ? 189.180 163.411 134.452 1.00 40.29  ? 198  ILE C CA  1 
ATOM   7193  C C   . ILE B 2 180 ? 190.008 163.057 135.675 1.00 40.29  ? 198  ILE C C   1 
ATOM   7194  O O   . ILE B 2 180 ? 189.782 162.069 136.370 1.00 40.29  ? 198  ILE C O   1 
ATOM   7195  C CB  . ILE B 2 180 ? 189.933 163.108 133.153 1.00 57.27  ? 198  ILE C CB  1 
ATOM   7196  C CG1 . ILE B 2 180 ? 188.902 163.056 132.012 1.00 57.27  ? 198  ILE C CG1 1 
ATOM   7197  C CG2 . ILE B 2 180 ? 190.731 161.796 133.230 1.00 57.27  ? 198  ILE C CG2 1 
ATOM   7198  C CD1 . ILE B 2 180 ? 189.531 163.141 130.624 1.00 57.27  ? 198  ILE C CD1 1 
ATOM   7199  N N   . LEU B 2 181 ? 190.959 163.909 135.986 1.00 40.29  ? 199  LEU C N   1 
ATOM   7200  C CA  . LEU B 2 181 ? 191.747 163.719 137.178 1.00 40.29  ? 199  LEU C CA  1 
ATOM   7201  C C   . LEU B 2 181 ? 190.833 163.765 138.396 1.00 40.29  ? 199  LEU C C   1 
ATOM   7202  O O   . LEU B 2 181 ? 190.918 162.896 139.268 1.00 40.29  ? 199  LEU C O   1 
ATOM   7203  C CB  . LEU B 2 181 ? 192.803 164.805 137.159 1.00 57.27  ? 199  LEU C CB  1 
ATOM   7204  C CG  . LEU B 2 181 ? 193.692 164.706 135.914 1.00 57.27  ? 199  LEU C CG  1 
ATOM   7205  C CD1 . LEU B 2 181 ? 194.556 165.941 135.814 1.00 57.27  ? 199  LEU C CD1 1 
ATOM   7206  C CD2 . LEU B 2 181 ? 194.591 163.490 135.972 1.00 57.27  ? 199  LEU C CD2 1 
ATOM   7207  N N   . ARG B 2 182 ? 189.846 164.675 138.415 1.00 40.29  ? 200  ARG C N   1 
ATOM   7208  C CA  . ARG B 2 182 ? 188.971 164.680 139.578 1.00 40.29  ? 200  ARG C CA  1 
ATOM   7209  C C   . ARG B 2 182 ? 188.135 163.406 139.665 1.00 40.29  ? 200  ARG C C   1 
ATOM   7210  O O   . ARG B 2 182 ? 187.979 162.843 140.743 1.00 40.29  ? 200  ARG C O   1 
ATOM   7211  C CB  . ARG B 2 182 ? 188.037 165.876 139.581 1.00 58.58  ? 200  ARG C CB  1 
ATOM   7212  C CG  . ARG B 2 182 ? 187.000 165.883 140.730 1.00 58.58  ? 200  ARG C CG  1 
ATOM   7213  C CD  . ARG B 2 182 ? 187.592 165.902 142.110 1.00 58.58  ? 200  ARG C CD  1 
ATOM   7214  N NE  . ARG B 2 182 ? 188.327 167.122 142.392 1.00 58.58  ? 200  ARG C NE  1 
ATOM   7215  C CZ  . ARG B 2 182 ? 187.768 168.275 142.822 1.00 58.58  ? 200  ARG C CZ  1 
ATOM   7216  N NH1 . ARG B 2 182 ? 188.535 169.303 143.070 1.00 58.58  ? 200  ARG C NH1 1 
ATOM   7217  N NH2 . ARG B 2 182 ? 186.461 168.378 143.001 1.00 58.58  ? 200  ARG C NH2 1 
ATOM   7218  N N   . PHE B 2 183 ? 187.657 162.911 138.532 1.00 40.29  ? 201  PHE C N   1 
ATOM   7219  C CA  . PHE B 2 183 ? 186.870 161.683 138.453 1.00 40.29  ? 201  PHE C CA  1 
ATOM   7220  C C   . PHE B 2 183 ? 187.557 160.533 139.138 1.00 40.29  ? 201  PHE C C   1 
ATOM   7221  O O   . PHE B 2 183 ? 186.959 159.798 139.922 1.00 40.29  ? 201  PHE C O   1 
ATOM   7222  C CB  . PHE B 2 183 ? 186.630 161.333 136.999 1.00 54.49  ? 201  PHE C CB  1 
ATOM   7223  C CG  . PHE B 2 183 ? 186.152 159.992 136.745 1.00 54.49  ? 201  PHE C CG  1 
ATOM   7224  C CD1 . PHE B 2 183 ? 184.839 159.625 136.848 1.00 54.49  ? 201  PHE C CD1 1 
ATOM   7225  C CD2 . PHE B 2 183 ? 187.089 159.052 136.357 1.00 54.49  ? 201  PHE C CD2 1 
ATOM   7226  C CE1 . PHE B 2 183 ? 184.479 158.325 136.554 1.00 54.49  ? 201  PHE C CE1 1 
ATOM   7227  C CE2 . PHE B 2 183 ? 186.745 157.782 136.072 1.00 54.49  ? 201  PHE C CE2 1 
ATOM   7228  C CZ  . PHE B 2 183 ? 185.439 157.410 136.160 1.00 54.49  ? 201  PHE C CZ  1 
ATOM   7229  N N   . PHE B 2 184 ? 188.842 160.421 138.823 1.00 40.29  ? 202  PHE C N   1 
ATOM   7230  C CA  . PHE B 2 184 ? 189.756 159.436 139.343 1.00 40.29  ? 202  PHE C CA  1 
ATOM   7231  C C   . PHE B 2 184 ? 190.213 159.687 140.764 1.00 40.29  ? 202  PHE C C   1 
ATOM   7232  O O   . PHE B 2 184 ? 191.003 158.904 141.282 1.00 40.29  ? 202  PHE C O   1 
ATOM   7233  C CB  . PHE B 2 184 ? 190.975 159.446 138.438 1.00 54.49  ? 202  PHE C CB  1 
ATOM   7234  C CG  . PHE B 2 184 ? 190.837 158.555 137.250 1.00 54.49  ? 202  PHE C CG  1 
ATOM   7235  C CD1 . PHE B 2 184 ? 190.657 157.180 137.443 1.00 54.49  ? 202  PHE C CD1 1 
ATOM   7236  C CD2 . PHE B 2 184 ? 190.995 159.067 135.957 1.00 54.49  ? 202  PHE C CD2 1 
ATOM   7237  C CE1 . PHE B 2 184 ? 190.632 156.316 136.340 1.00 54.49  ? 202  PHE C CE1 1 
ATOM   7238  C CE2 . PHE B 2 184 ? 190.976 158.200 134.856 1.00 54.49  ? 202  PHE C CE2 1 
ATOM   7239  C CZ  . PHE B 2 184 ? 190.797 156.822 135.044 1.00 54.49  ? 202  PHE C CZ  1 
ATOM   7240  N N   . ASN B 2 185 ? 189.766 160.791 141.351 1.00 40.29  ? 203  ASN C N   1 
ATOM   7241  C CA  . ASN B 2 185 ? 190.286 161.164 142.652 1.00 40.29  ? 203  ASN C CA  1 
ATOM   7242  C C   . ASN B 2 185 ? 191.731 161.400 142.324 1.00 40.29  ? 203  ASN C C   1 
ATOM   7243  O O   . ASN B 2 185 ? 192.521 161.794 143.177 1.00 40.29  ? 203  ASN C O   1 
ATOM   7244  C CB  . ASN B 2 185 ? 190.106 160.063 143.682 1.00 53.59  ? 203  ASN C CB  1 
ATOM   7245  C CG  . ASN B 2 185 ? 188.664 159.621 143.808 1.00 53.59  ? 203  ASN C CG  1 
ATOM   7246  O OD1 . ASN B 2 185 ? 187.817 159.989 142.995 1.00 53.59  ? 203  ASN C OD1 1 
ATOM   7247  N ND2 . ASN B 2 185 ? 188.377 158.823 144.829 1.00 53.59  ? 203  ASN C ND2 1 
ATOM   7248  N N   . TRP B 2 186 ? 192.082 161.158 141.069 1.00 40.29  ? 204  TRP C N   1 
ATOM   7249  C CA  . TRP B 2 186 ? 193.435 161.372 140.622 1.00 40.29  ? 204  TRP C CA  1 
ATOM   7250  C C   . TRP B 2 186 ? 193.724 162.843 140.747 1.00 40.29  ? 204  TRP C C   1 
ATOM   7251  O O   . TRP B 2 186 ? 192.861 163.672 140.486 1.00 40.29  ? 204  TRP C O   1 
ATOM   7252  C CB  . TRP B 2 186 ? 193.515 160.927 139.177 1.00 53.94  ? 204  TRP C CB  1 
ATOM   7253  N N   . THR B 2 187 ? 194.932 163.193 141.158 1.00 46.89  ? 205  THR C N   1 
ATOM   7254  C CA  . THR B 2 187 ? 195.237 164.599 141.374 1.00 46.89  ? 205  THR C CA  1 
ATOM   7255  C C   . THR B 2 187 ? 196.682 164.947 141.132 1.00 46.89  ? 205  THR C C   1 
ATOM   7256  O O   . THR B 2 187 ? 197.014 165.644 140.180 1.00 46.89  ? 205  THR C O   1 
ATOM   7257  C CB  . THR B 2 187 ? 194.938 164.995 142.828 1.00 64.19  ? 205  THR C CB  1 
ATOM   7258  O OG1 . THR B 2 187 ? 195.557 164.052 143.712 1.00 64.19  ? 205  THR C OG1 1 
ATOM   7259  C CG2 . THR B 2 187 ? 193.439 165.017 143.091 1.00 64.19  ? 205  THR C CG2 1 
ATOM   7260  N N   . TYR B 2 188 ? 197.549 164.475 142.002 1.00 48.81  ? 206  TYR C N   1 
ATOM   7261  C CA  . TYR B 2 188 ? 198.963 164.797 141.911 1.00 48.81  ? 206  TYR C CA  1 
ATOM   7262  C C   . TYR B 2 188 ? 199.599 164.062 140.733 1.00 48.81  ? 206  TYR C C   1 
ATOM   7263  O O   . TYR B 2 188 ? 199.467 162.844 140.655 1.00 48.81  ? 206  TYR C O   1 
ATOM   7264  C CB  . TYR B 2 188 ? 199.574 164.433 143.256 1.00 65.52  ? 206  TYR C CB  1 
ATOM   7265  C CG  . TYR B 2 188 ? 201.047 164.688 143.247 1.00 65.52  ? 206  TYR C CG  1 
ATOM   7266  C CD1 . TYR B 2 188 ? 201.891 163.686 142.766 1.00 65.52  ? 206  TYR C CD1 1 
ATOM   7267  C CD2 . TYR B 2 188 ? 201.557 165.947 143.587 1.00 65.52  ? 206  TYR C CD2 1 
ATOM   7268  C CE1 . TYR B 2 188 ? 203.258 163.932 142.615 1.00 65.52  ? 206  TYR C CE1 1 
ATOM   7269  C CE2 . TYR B 2 188 ? 202.940 166.182 143.499 1.00 65.52  ? 206  TYR C CE2 1 
ATOM   7270  C CZ  . TYR B 2 188 ? 203.795 165.162 143.036 1.00 65.52  ? 206  TYR C CZ  1 
ATOM   7271  O OH  . TYR B 2 188 ? 205.134 165.371 142.981 1.00 65.52  ? 206  TYR C OH  1 
ATOM   7272  N N   . VAL B 2 189 ? 200.223 164.775 139.784 1.00 40.29  ? 207  VAL C N   1 
ATOM   7273  C CA  . VAL B 2 189 ? 200.450 164.213 138.430 1.00 40.29  ? 207  VAL C CA  1 
ATOM   7274  C C   . VAL B 2 189 ? 201.521 164.920 137.587 1.00 40.29  ? 207  VAL C C   1 
ATOM   7275  O O   . VAL B 2 189 ? 201.648 166.134 137.635 1.00 40.29  ? 207  VAL C O   1 
ATOM   7276  C CB  . VAL B 2 189 ? 199.105 164.218 137.681 1.00 56.74  ? 207  VAL C CB  1 
ATOM   7277  C CG1 . VAL B 2 189 ? 198.540 165.626 137.475 1.00 56.74  ? 207  VAL C CG1 1 
ATOM   7278  C CG2 . VAL B 2 189 ? 199.167 163.524 136.320 1.00 56.74  ? 207  VAL C CG2 1 
ATOM   7279  N N   . SER B 2 190 ? 202.276 164.195 136.763 1.00 40.29  ? 208  SER C N   1 
ATOM   7280  C CA  . SER B 2 190 ? 203.236 164.802 135.817 1.00 40.29  ? 208  SER C CA  1 
ATOM   7281  C C   . SER B 2 190 ? 202.586 165.166 134.482 1.00 40.29  ? 208  SER C C   1 
ATOM   7282  O O   . SER B 2 190 ? 201.647 164.503 134.057 1.00 40.29  ? 208  SER C O   1 
ATOM   7283  C CB  . SER B 2 190 ? 204.409 163.862 135.564 1.00 53.09  ? 208  SER C CB  1 
ATOM   7284  O OG  . SER B 2 190 ? 205.047 163.520 136.775 1.00 53.09  ? 208  SER C OG  1 
ATOM   7285  N N   . THR B 2 191 ? 203.056 166.179 133.761 1.00 40.29  ? 209  THR C N   1 
ATOM   7286  C CA  . THR B 2 191 ? 202.379 166.625 132.528 1.00 40.29  ? 209  THR C CA  1 
ATOM   7287  C C   . THR B 2 191 ? 203.326 167.097 131.437 1.00 40.29  ? 209  THR C C   1 
ATOM   7288  O O   . THR B 2 191 ? 204.489 167.388 131.675 1.00 40.29  ? 209  THR C O   1 
ATOM   7289  C CB  . THR B 2 191 ? 201.344 167.720 132.799 1.00 55.15  ? 209  THR C CB  1 
ATOM   7290  O OG1 . THR B 2 191 ? 201.994 168.925 133.089 1.00 55.15  ? 209  THR C OG1 1 
ATOM   7291  C CG2 . THR B 2 191 ? 200.408 167.427 133.965 1.00 55.15  ? 209  THR C CG2 1 
ATOM   7292  N N   . VAL B 2 192 ? 202.848 167.139 130.202 1.00 40.29  ? 210  VAL C N   1 
ATOM   7293  C CA  . VAL B 2 192 ? 203.698 167.391 129.046 1.00 40.29  ? 210  VAL C CA  1 
ATOM   7294  C C   . VAL B 2 192 ? 202.960 168.185 127.984 1.00 40.29  ? 210  VAL C C   1 
ATOM   7295  O O   . VAL B 2 192 ? 201.785 167.942 127.723 1.00 40.29  ? 210  VAL C O   1 
ATOM   7296  C CB  . VAL B 2 192 ? 204.186 166.054 128.480 1.00 56.74  ? 210  VAL C CB  1 
ATOM   7297  C CG1 . VAL B 2 192 ? 205.089 166.269 127.276 1.00 56.74  ? 210  VAL C CG1 1 
ATOM   7298  C CG2 . VAL B 2 192 ? 204.989 165.245 129.499 1.00 56.74  ? 210  VAL C CG2 1 
ATOM   7299  N N   . ALA B 2 193 ? 203.667 169.088 127.317 1.00 40.29  ? 211  ALA C N   1 
ATOM   7300  C CA  . ALA B 2 193 ? 203.268 169.661 126.043 1.00 40.29  ? 211  ALA C CA  1 
ATOM   7301  C C   . ALA B 2 193 ? 204.214 169.185 124.944 1.00 40.29  ? 211  ALA C C   1 
ATOM   7302  O O   . ALA B 2 193 ? 205.365 168.849 125.200 1.00 40.29  ? 211  ALA C O   1 
ATOM   7303  C CB  . ALA B 2 193 ? 203.247 171.183 126.135 1.00 54.43  ? 211  ALA C CB  1 
ATOM   7304  N N   . SER B 2 194 ? 203.796 169.251 123.691 1.00 52.74  ? 212  SER C N   1 
ATOM   7305  C CA  . SER B 2 194 ? 204.758 169.347 122.592 1.00 52.74  ? 212  SER C CA  1 
ATOM   7306  C C   . SER B 2 194 ? 205.521 170.674 122.656 1.00 52.74  ? 212  SER C C   1 
ATOM   7307  O O   . SER B 2 194 ? 205.266 171.541 123.485 1.00 52.74  ? 212  SER C O   1 
ATOM   7308  C CB  . SER B 2 194 ? 204.022 169.232 121.265 1.00 70.25  ? 212  SER C CB  1 
ATOM   7309  O OG  . SER B 2 194 ? 202.999 170.200 121.229 1.00 70.25  ? 212  SER C OG  1 
ATOM   7310  N N   . GLU B 2 195 ? 206.430 170.898 121.720 1.00 62.75  ? 213  GLU C N   1 
ATOM   7311  C CA  . GLU B 2 195 ? 206.987 172.215 121.413 1.00 62.75  ? 213  GLU C CA  1 
ATOM   7312  C C   . GLU B 2 195 ? 205.919 173.213 120.923 1.00 62.75  ? 213  GLU C C   1 
ATOM   7313  O O   . GLU B 2 195 ? 206.223 174.379 120.687 1.00 62.75  ? 213  GLU C O   1 
ATOM   7314  C CB  . GLU B 2 195 ? 208.129 172.087 120.409 1.00 82.70  ? 213  GLU C CB  1 
ATOM   7315  C CG  . GLU B 2 195 ? 207.711 171.421 119.097 1.00 82.70  ? 213  GLU C CG  1 
ATOM   7316  C CD  . GLU B 2 195 ? 208.733 171.702 117.998 1.00 82.70  ? 213  GLU C CD  1 
ATOM   7317  O OE1 . GLU B 2 195 ? 208.864 172.860 117.557 1.00 82.70  ? 213  GLU C OE1 1 
ATOM   7318  O OE2 . GLU B 2 195 ? 209.348 170.742 117.492 1.00 82.70  ? 213  GLU C OE2 1 
ATOM   7319  N N   . GLY B 2 196 ? 204.662 172.787 120.815 1.00 59.17  ? 214  GLY C N   1 
ATOM   7320  C CA  . GLY B 2 196 ? 203.543 173.637 120.470 1.00 59.17  ? 214  GLY C CA  1 
ATOM   7321  C C   . GLY B 2 196 ? 203.402 174.835 121.385 1.00 59.17  ? 214  GLY C C   1 
ATOM   7322  O O   . GLY B 2 196 ? 203.405 174.716 122.603 1.00 59.17  ? 214  GLY C O   1 
ATOM   7323  N N   . ASP B 2 197 ? 203.174 175.987 120.792 1.00 60.02  ? 215  ASP C N   1 
ATOM   7324  C CA  . ASP B 2 197 ? 202.580 177.128 121.470 1.00 60.02  ? 215  ASP C CA  1 
ATOM   7325  C C   . ASP B 2 197 ? 201.130 176.835 121.848 1.00 60.02  ? 215  ASP C C   1 
ATOM   7326  O O   . ASP B 2 197 ? 200.670 177.195 122.925 1.00 60.02  ? 215  ASP C O   1 
ATOM   7327  C CB  . ASP B 2 197 ? 202.655 178.352 120.558 1.00 77.04  ? 215  ASP C CB  1 
ATOM   7328  C CG  . ASP B 2 197 ? 201.991 178.181 119.185 1.00 77.04  ? 215  ASP C CG  1 
ATOM   7329  O OD1 . ASP B 2 197 ? 201.770 177.037 118.726 1.00 77.04  ? 215  ASP C OD1 1 
ATOM   7330  O OD2 . ASP B 2 197 ? 201.671 179.222 118.576 1.00 77.04  ? 215  ASP C OD2 1 
ATOM   7331  N N   . TYR B 2 198 ? 200.418 176.077 121.026 1.00 55.55  ? 216  TYR C N   1 
ATOM   7332  C CA  . TYR B 2 198 ? 199.189 175.415 121.435 1.00 55.55  ? 216  TYR C CA  1 
ATOM   7333  C C   . TYR B 2 198 ? 199.458 174.495 122.636 1.00 55.55  ? 216  TYR C C   1 
ATOM   7334  O O   . TYR B 2 198 ? 198.663 174.422 123.561 1.00 55.55  ? 216  TYR C O   1 
ATOM   7335  C CB  . TYR B 2 198 ? 198.652 174.646 120.230 1.00 74.56  ? 216  TYR C CB  1 
ATOM   7336  C CG  . TYR B 2 198 ? 199.592 173.574 119.729 1.00 74.56  ? 216  TYR C CG  1 
ATOM   7337  C CD1 . TYR B 2 198 ? 199.606 172.319 120.357 1.00 74.56  ? 216  TYR C CD1 1 
ATOM   7338  C CD2 . TYR B 2 198 ? 200.483 173.846 118.677 1.00 74.56  ? 216  TYR C CD2 1 
ATOM   7339  C CE1 . TYR B 2 198 ? 200.537 171.347 119.961 1.00 74.56  ? 216  TYR C CE1 1 
ATOM   7340  C CE2 . TYR B 2 198 ? 201.395 172.863 118.254 1.00 74.56  ? 216  TYR C CE2 1 
ATOM   7341  C CZ  . TYR B 2 198 ? 201.434 171.615 118.907 1.00 74.56  ? 216  TYR C CZ  1 
ATOM   7342  O OH  . TYR B 2 198 ? 202.387 170.700 118.585 1.00 74.56  ? 216  TYR C OH  1 
ATOM   7343  N N   . GLY B 2 199 ? 200.632 173.867 122.681 1.00 45.62  ? 217  GLY C N   1 
ATOM   7344  C CA  . GLY B 2 199 ? 201.099 173.071 123.808 1.00 45.62  ? 217  GLY C CA  1 
ATOM   7345  C C   . GLY B 2 199 ? 201.215 173.935 125.059 1.00 45.62  ? 217  GLY C C   1 
ATOM   7346  O O   . GLY B 2 199 ? 200.611 173.621 126.076 1.00 45.62  ? 217  GLY C O   1 
ATOM   7347  N N   . GLU B 2 200 ? 201.900 175.070 124.971 1.00 47.99  ? 218  GLU C N   1 
ATOM   7348  C CA  . GLU B 2 200 ? 201.958 176.050 126.061 1.00 47.99  ? 218  GLU C CA  1 
ATOM   7349  C C   . GLU B 2 200 ? 200.566 176.481 126.476 1.00 47.99  ? 218  GLU C C   1 
ATOM   7350  O O   . GLU B 2 200 ? 200.240 176.504 127.649 1.00 47.99  ? 218  GLU C O   1 
ATOM   7351  C CB  . GLU B 2 200 ? 202.670 177.330 125.623 1.00 63.25  ? 218  GLU C CB  1 
ATOM   7352  C CG  . GLU B 2 200 ? 204.109 177.121 125.179 1.00 63.25  ? 218  GLU C CG  1 
ATOM   7353  C CD  . GLU B 2 200 ? 204.597 178.222 124.232 1.00 63.25  ? 218  GLU C CD  1 
ATOM   7354  O OE1 . GLU B 2 200 ? 204.025 179.332 124.213 1.00 63.25  ? 218  GLU C OE1 1 
ATOM   7355  O OE2 . GLU B 2 200 ? 205.563 177.952 123.486 1.00 63.25  ? 218  GLU C OE2 1 
ATOM   7356  N N   . THR B 2 201 ? 199.727 176.786 125.499 1.00 40.97  ? 219  THR C N   1 
ATOM   7357  C CA  . THR B 2 201 ? 198.372 177.258 125.717 1.00 40.97  ? 219  THR C CA  1 
ATOM   7358  C C   . THR B 2 201 ? 197.581 176.241 126.509 1.00 40.97  ? 219  THR C C   1 
ATOM   7359  O O   . THR B 2 201 ? 196.975 176.570 127.519 1.00 40.97  ? 219  THR C O   1 
ATOM   7360  C CB  . THR B 2 201 ? 197.692 177.474 124.370 1.00 56.08  ? 219  THR C CB  1 
ATOM   7361  O OG1 . THR B 2 201 ? 198.391 178.432 123.615 1.00 56.08  ? 219  THR C OG1 1 
ATOM   7362  C CG2 . THR B 2 201 ? 196.253 177.936 124.509 1.00 56.08  ? 219  THR C CG2 1 
ATOM   7363  N N   . GLY B 2 202 ? 197.603 174.992 126.063 1.00 40.29  ? 220  GLY C N   1 
ATOM   7364  C CA  . GLY B 2 202 ? 196.946 173.900 126.742 1.00 40.29  ? 220  GLY C CA  1 
ATOM   7365  C C   . GLY B 2 202 ? 197.536 173.681 128.123 1.00 40.29  ? 220  GLY C C   1 
ATOM   7366  O O   . GLY B 2 202 ? 196.790 173.487 129.073 1.00 40.29  ? 220  GLY C O   1 
ATOM   7367  N N   . ILE B 2 203 ? 198.854 173.759 128.273 1.00 40.29  ? 221  ILE C N   1 
ATOM   7368  C CA  . ILE B 2 203 ? 199.499 173.549 129.562 1.00 40.29  ? 221  ILE C CA  1 
ATOM   7369  C C   . ILE B 2 203 ? 199.151 174.663 130.530 1.00 40.29  ? 221  ILE C C   1 
ATOM   7370  O O   . ILE B 2 203 ? 198.706 174.373 131.633 1.00 40.29  ? 221  ILE C O   1 
ATOM   7371  C CB  . ILE B 2 203 ? 201.011 173.379 129.365 1.00 57.27  ? 221  ILE C CB  1 
ATOM   7372  C CG1 . ILE B 2 203 ? 201.326 171.933 128.937 1.00 57.27  ? 221  ILE C CG1 1 
ATOM   7373  C CG2 . ILE B 2 203 ? 201.834 173.752 130.599 1.00 57.27  ? 221  ILE C CG2 1 
ATOM   7374  C CD1 . ILE B 2 203 ? 201.114 170.840 129.992 1.00 57.27  ? 221  ILE C CD1 1 
ATOM   7375  N N   . GLU B 2 204 ? 199.268 175.922 130.120 1.00 40.29  ? 222  GLU C N   1 
ATOM   7376  C CA  . GLU B 2 204 ? 198.804 176.996 130.958 1.00 40.29  ? 222  GLU C CA  1 
ATOM   7377  C C   . GLU B 2 204 ? 197.351 176.793 131.281 1.00 40.29  ? 222  GLU C C   1 
ATOM   7378  O O   . GLU B 2 204 ? 196.937 176.970 132.429 1.00 40.29  ? 222  GLU C O   1 
ATOM   7379  C CB  . GLU B 2 204 ? 198.962 178.322 130.239 1.00 54.07  ? 222  GLU C CB  1 
ATOM   7380  C CG  . GLU B 2 204 ? 200.382 178.776 130.067 1.00 54.07  ? 222  GLU C CG  1 
ATOM   7381  C CD  . GLU B 2 204 ? 200.474 179.985 129.204 1.00 54.07  ? 222  GLU C CD  1 
ATOM   7382  O OE1 . GLU B 2 204 ? 199.466 180.376 128.663 1.00 54.07  ? 222  GLU C OE1 1 
ATOM   7383  O OE2 . GLU B 2 204 ? 201.545 180.525 129.078 1.00 54.07  ? 222  GLU C OE2 1 
ATOM   7384  N N   . ALA B 2 205 ? 196.506 176.501 130.296 1.00 40.29  ? 223  ALA C N   1 
ATOM   7385  C CA  . ALA B 2 205 ? 195.079 176.378 130.551 1.00 40.29  ? 223  ALA C CA  1 
ATOM   7386  C C   . ALA B 2 205 ? 194.817 175.251 131.549 1.00 40.29  ? 223  ALA C C   1 
ATOM   7387  O O   . ALA B 2 205 ? 194.032 175.382 132.484 1.00 40.29  ? 223  ALA C O   1 
ATOM   7388  C CB  . ALA B 2 205 ? 194.359 176.146 129.224 1.00 54.43  ? 223  ALA C CB  1 
ATOM   7389  N N   . PHE B 2 206 ? 195.524 174.147 131.370 1.00 40.29  ? 224  PHE C N   1 
ATOM   7390  C CA  . PHE B 2 206 ? 195.446 173.012 132.242 1.00 40.29  ? 224  PHE C CA  1 
ATOM   7391  C C   . PHE B 2 206 ? 195.862 173.388 133.647 1.00 40.29  ? 224  PHE C C   1 
ATOM   7392  O O   . PHE B 2 206 ? 195.124 173.100 134.571 1.00 40.29  ? 224  PHE C O   1 
ATOM   7393  C CB  . PHE B 2 206 ? 196.283 171.877 131.684 1.00 54.49  ? 224  PHE C CB  1 
ATOM   7394  C CG  . PHE B 2 206 ? 196.266 170.741 132.658 1.00 54.49  ? 224  PHE C CG  1 
ATOM   7395  C CD1 . PHE B 2 206 ? 195.098 169.970 132.801 1.00 54.49  ? 224  PHE C CD1 1 
ATOM   7396  C CD2 . PHE B 2 206 ? 197.343 170.583 133.540 1.00 54.49  ? 224  PHE C CD2 1 
ATOM   7397  C CE1 . PHE B 2 206 ? 195.014 169.018 133.824 1.00 54.49  ? 224  PHE C CE1 1 
ATOM   7398  C CE2 . PHE B 2 206 ? 197.260 169.625 134.558 1.00 54.49  ? 224  PHE C CE2 1 
ATOM   7399  C CZ  . PHE B 2 206 ? 196.103 168.845 134.695 1.00 54.49  ? 224  PHE C CZ  1 
ATOM   7400  N N   . GLU B 2 207 ? 196.978 174.079 133.823 1.00 40.29  ? 225  GLU C N   1 
ATOM   7401  C CA  . GLU B 2 207 ? 197.378 174.562 135.136 1.00 40.29  ? 225  GLU C CA  1 
ATOM   7402  C C   . GLU B 2 207 ? 196.278 175.386 135.785 1.00 40.29  ? 225  GLU C C   1 
ATOM   7403  O O   . GLU B 2 207 ? 195.978 175.202 136.964 1.00 40.29  ? 225  GLU C O   1 
ATOM   7404  C CB  . GLU B 2 207 ? 198.585 175.476 135.007 1.00 53.10  ? 225  GLU C CB  1 
ATOM   7405  C CG  . GLU B 2 207 ? 199.855 174.764 134.559 1.00 53.10  ? 225  GLU C CG  1 
ATOM   7406  C CD  . GLU B 2 207 ? 200.855 175.749 133.932 1.00 53.10  ? 225  GLU C CD  1 
ATOM   7407  O OE1 . GLU B 2 207 ? 200.681 176.982 134.060 1.00 53.10  ? 225  GLU C OE1 1 
ATOM   7408  O OE2 . GLU B 2 207 ? 201.876 175.286 133.389 1.00 53.10  ? 225  GLU C OE2 1 
ATOM   7409  N N   . LEU B 2 208 ? 195.611 176.267 135.055 1.00 40.29  ? 226  LEU C N   1 
ATOM   7410  C CA  . LEU B 2 208 ? 194.529 177.040 135.643 1.00 40.29  ? 226  LEU C CA  1 
ATOM   7411  C C   . LEU B 2 208 ? 193.395 176.137 136.125 1.00 40.29  ? 226  LEU C C   1 
ATOM   7412  O O   . LEU B 2 208 ? 193.005 176.179 137.292 1.00 40.29  ? 226  LEU C O   1 
ATOM   7413  C CB  . LEU B 2 208 ? 194.049 178.058 134.611 1.00 57.27  ? 226  LEU C CB  1 
ATOM   7414  C CG  . LEU B 2 208 ? 195.107 179.145 134.378 1.00 57.27  ? 226  LEU C CG  1 
ATOM   7415  C CD1 . LEU B 2 208 ? 194.925 179.787 133.006 1.00 57.27  ? 226  LEU C CD1 1 
ATOM   7416  C CD2 . LEU B 2 208 ? 194.976 180.228 135.445 1.00 57.27  ? 226  LEU C CD2 1 
ATOM   7417  N N   . GLU B 2 209 ? 192.894 175.276 135.251 1.00 40.29  ? 227  GLU C N   1 
ATOM   7418  C CA  . GLU B 2 209 ? 191.805 174.361 135.589 1.00 40.29  ? 227  GLU C CA  1 
ATOM   7419  C C   . GLU B 2 209 ? 192.185 173.394 136.707 1.00 40.29  ? 227  GLU C C   1 
ATOM   7420  O O   . GLU B 2 209 ? 191.370 173.050 137.569 1.00 40.29  ? 227  GLU C O   1 
ATOM   7421  C CB  . GLU B 2 209 ? 191.420 173.557 134.339 1.00 53.10  ? 227  GLU C CB  1 
ATOM   7422  C CG  . GLU B 2 209 ? 190.795 174.426 133.242 1.00 53.10  ? 227  GLU C CG  1 
ATOM   7423  C CD  . GLU B 2 209 ? 189.621 175.262 133.758 1.00 53.10  ? 227  GLU C CD  1 
ATOM   7424  O OE1 . GLU B 2 209 ? 188.793 174.741 134.540 1.00 53.10  ? 227  GLU C OE1 1 
ATOM   7425  O OE2 . GLU B 2 209 ? 189.534 176.452 133.389 1.00 53.10  ? 227  GLU C OE2 1 
ATOM   7426  N N   . ALA B 2 210 ? 193.441 172.978 136.706 1.00 40.29  ? 228  ALA C N   1 
ATOM   7427  C CA  . ALA B 2 210 ? 194.005 172.099 137.694 1.00 40.29  ? 228  ALA C CA  1 
ATOM   7428  C C   . ALA B 2 210 ? 194.015 172.784 139.042 1.00 40.29  ? 228  ALA C C   1 
ATOM   7429  O O   . ALA B 2 210 ? 193.479 172.238 140.009 1.00 40.29  ? 228  ALA C O   1 
ATOM   7430  C CB  . ALA B 2 210 ? 195.417 171.707 137.251 1.00 54.43  ? 228  ALA C CB  1 
ATOM   7431  N N   . ARG B 2 211 ? 194.541 174.011 139.120 1.00 42.42  ? 229  ARG C N   1 
ATOM   7432  C CA  . ARG B 2 211 ? 194.600 174.656 140.408 1.00 42.42  ? 229  ARG C CA  1 
ATOM   7433  C C   . ARG B 2 211 ? 193.214 174.881 140.942 1.00 42.42  ? 229  ARG C C   1 
ATOM   7434  O O   . ARG B 2 211 ? 192.971 174.673 142.125 1.00 42.42  ? 229  ARG C O   1 
ATOM   7435  C CB  . ARG B 2 211 ? 195.360 175.958 140.365 1.00 62.02  ? 229  ARG C CB  1 
ATOM   7436  C CG  . ARG B 2 211 ? 196.858 175.803 140.226 1.00 62.02  ? 229  ARG C CG  1 
ATOM   7437  C CD  . ARG B 2 211 ? 197.556 177.071 140.511 1.00 62.02  ? 229  ARG C CD  1 
ATOM   7438  N NE  . ARG B 2 211 ? 197.232 178.119 139.552 1.00 62.02  ? 229  ARG C NE  1 
ATOM   7439  C CZ  . ARG B 2 211 ? 197.879 178.350 138.388 1.00 62.02  ? 229  ARG C CZ  1 
ATOM   7440  N NH1 . ARG B 2 211 ? 197.490 179.340 137.621 1.00 62.02  ? 229  ARG C NH1 1 
ATOM   7441  N NH2 . ARG B 2 211 ? 198.896 177.616 138.013 1.00 62.02  ? 229  ARG C NH2 1 
ATOM   7442  N N   . ALA B 2 212 ? 192.270 175.220 140.066 1.00 40.29  ? 230  ALA C N   1 
ATOM   7443  C CA  . ALA B 2 212 ? 190.903 175.457 140.491 1.00 40.29  ? 230  ALA C CA  1 
ATOM   7444  C C   . ALA B 2 212 ? 190.329 174.229 141.184 1.00 40.29  ? 230  ALA C C   1 
ATOM   7445  O O   . ALA B 2 212 ? 189.535 174.340 142.120 1.00 40.29  ? 230  ALA C O   1 
ATOM   7446  C CB  . ALA B 2 212 ? 190.039 175.818 139.299 1.00 54.43  ? 230  ALA C CB  1 
ATOM   7447  N N   . ARG B 2 213 ? 190.751 173.055 140.737 1.00 40.29  ? 231  ARG C N   1 
ATOM   7448  C CA  . ARG B 2 213 ? 190.295 171.794 141.277 1.00 40.29  ? 231  ARG C CA  1 
ATOM   7449  C C   . ARG B 2 213 ? 191.282 171.163 142.258 1.00 40.29  ? 231  ARG C C   1 
ATOM   7450  O O   . ARG B 2 213 ? 191.138 169.991 142.625 1.00 40.29  ? 231  ARG C O   1 
ATOM   7451  C CB  . ARG B 2 213 ? 189.996 170.850 140.147 1.00 56.58  ? 231  ARG C CB  1 
ATOM   7452  C CG  . ARG B 2 213 ? 188.801 171.259 139.323 1.00 56.58  ? 231  ARG C CG  1 
ATOM   7453  C CD  . ARG B 2 213 ? 188.776 170.528 138.066 1.00 56.58  ? 231  ARG C CD  1 
ATOM   7454  N NE  . ARG B 2 213 ? 187.640 170.851 137.219 1.00 56.58  ? 231  ARG C NE  1 
ATOM   7455  C CZ  . ARG B 2 213 ? 187.541 171.972 136.462 1.00 56.58  ? 231  ARG C CZ  1 
ATOM   7456  N NH1 . ARG B 2 213 ? 186.481 172.169 135.681 1.00 56.58  ? 231  ARG C NH1 1 
ATOM   7457  N NH2 . ARG B 2 213 ? 188.504 172.877 136.494 1.00 56.58  ? 231  ARG C NH2 1 
ATOM   7458  N N   . ASN B 2 214 ? 192.264 171.941 142.707 1.00 44.37  ? 232  ASN C N   1 
ATOM   7459  C CA  . ASN B 2 214 ? 193.291 171.510 143.642 1.00 44.37  ? 232  ASN C CA  1 
ATOM   7460  C C   . ASN B 2 214 ? 194.107 170.330 143.150 1.00 44.37  ? 232  ASN C C   1 
ATOM   7461  O O   . ASN B 2 214 ? 194.471 169.431 143.911 1.00 44.37  ? 232  ASN C O   1 
ATOM   7462  C CB  . ASN B 2 214 ? 192.664 171.193 144.981 1.00 59.97  ? 232  ASN C CB  1 
ATOM   7463  C CG  . ASN B 2 214 ? 191.995 172.386 145.561 1.00 59.97  ? 232  ASN C CG  1 
ATOM   7464  O OD1 . ASN B 2 214 ? 192.539 173.497 145.538 1.00 59.97  ? 232  ASN C OD1 1 
ATOM   7465  N ND2 . ASN B 2 214 ? 190.813 172.191 146.088 1.00 59.97  ? 232  ASN C ND2 1 
ATOM   7466  N N   . ILE B 2 215 ? 194.421 170.360 141.876 1.00 48.21  ? 233  ILE C N   1 
ATOM   7467  C CA  . ILE B 2 215 ? 195.232 169.366 141.227 1.00 48.21  ? 233  ILE C CA  1 
ATOM   7468  C C   . ILE B 2 215 ? 196.627 169.966 141.018 1.00 48.21  ? 233  ILE C C   1 
ATOM   7469  O O   . ILE B 2 215 ? 196.760 171.062 140.464 1.00 48.21  ? 233  ILE C O   1 
ATOM   7470  C CB  . ILE B 2 215 ? 194.596 168.960 139.903 1.00 68.52  ? 233  ILE C CB  1 
ATOM   7471  C CG1 . ILE B 2 215 ? 193.208 168.334 140.167 1.00 68.52  ? 233  ILE C CG1 1 
ATOM   7472  C CG2 . ILE B 2 215 ? 195.533 168.025 139.132 1.00 68.52  ? 233  ILE C CG2 1 
ATOM   7473  C CD1 . ILE B 2 215 ? 192.344 168.180 138.934 1.00 68.52  ? 233  ILE C CD1 1 
ATOM   7474  N N   . CYS B 2 216 ? 197.655 169.263 141.509 1.00 52.62  ? 234  CYS C N   1 
ATOM   7475  C CA  . CYS B 2 216 ? 199.056 169.645 141.520 1.00 52.62  ? 234  CYS C CA  1 
ATOM   7476  C C   . CYS B 2 216 ? 199.853 168.943 140.429 1.00 52.62  ? 234  CYS C C   1 
ATOM   7477  O O   . CYS B 2 216 ? 199.731 167.724 140.236 1.00 52.62  ? 234  CYS C O   1 
ATOM   7478  C CB  . CYS B 2 216 ? 199.670 169.352 142.889 1.00 68.19  ? 234  CYS C CB  1 
ATOM   7479  S SG  . CYS B 2 216 ? 201.419 169.793 143.062 1.00 68.19  ? 234  CYS C SG  1 
ATOM   7480  N N   . VAL B 2 217 ? 200.704 169.714 139.763 1.00 39.62  ? 235  VAL C N   1 
ATOM   7481  C CA  . VAL B 2 217 ? 201.728 169.190 138.869 1.00 39.62  ? 235  VAL C CA  1 
ATOM   7482  C C   . VAL B 2 217 ? 202.877 168.638 139.684 1.00 39.62  ? 235  VAL C C   1 
ATOM   7483  O O   . VAL B 2 217 ? 203.563 169.372 140.384 1.00 39.62  ? 235  VAL C O   1 
ATOM   7484  C CB  . VAL B 2 217 ? 202.224 170.260 137.888 1.00 55.79  ? 235  VAL C CB  1 
ATOM   7485  C CG1 . VAL B 2 217 ? 203.425 169.776 137.074 1.00 55.79  ? 235  VAL C CG1 1 
ATOM   7486  C CG2 . VAL B 2 217 ? 201.101 170.612 136.908 1.00 55.79  ? 235  VAL C CG2 1 
ATOM   7487  N N   . ALA B 2 218 ? 203.130 167.351 139.542 1.00 40.29  ? 236  ALA C N   1 
ATOM   7488  C CA  . ALA B 2 218 ? 204.338 166.710 140.004 1.00 40.29  ? 236  ALA C CA  1 
ATOM   7489  C C   . ALA B 2 218 ? 205.572 167.297 139.307 1.00 40.29  ? 236  ALA C C   1 
ATOM   7490  O O   . ALA B 2 218 ? 206.523 167.720 139.962 1.00 40.29  ? 236  ALA C O   1 
ATOM   7491  C CB  . ALA B 2 218 ? 204.189 165.212 139.731 1.00 54.43  ? 236  ALA C CB  1 
ATOM   7492  N N   . THR B 2 219 ? 205.561 167.336 137.974 1.00 40.29  ? 237  THR C N   1 
ATOM   7493  C CA  . THR B 2 219 ? 206.577 167.987 137.133 1.00 40.29  ? 237  THR C CA  1 
ATOM   7494  C C   . THR B 2 219 ? 206.062 168.088 135.696 1.00 40.29  ? 237  THR C C   1 
ATOM   7495  O O   . THR B 2 219 ? 205.086 167.414 135.356 1.00 40.29  ? 237  THR C O   1 
ATOM   7496  C CB  . THR B 2 219 ? 207.911 167.223 137.189 1.00 55.15  ? 237  THR C CB  1 
ATOM   7497  O OG1 . THR B 2 219 ? 208.887 167.917 136.452 1.00 55.15  ? 237  THR C OG1 1 
ATOM   7498  C CG2 . THR B 2 219 ? 207.825 165.796 136.654 1.00 55.15  ? 237  THR C CG2 1 
ATOM   7499  N N   . SER B 2 220 ? 206.682 168.904 134.839 1.00 40.29  ? 238  SER C N   1 
ATOM   7500  C CA  . SER B 2 220 ? 206.271 169.020 133.437 1.00 40.29  ? 238  SER C CA  1 
ATOM   7501  C C   . SER B 2 220 ? 207.321 169.576 132.475 1.00 40.29  ? 238  SER C C   1 
ATOM   7502  O O   . SER B 2 220 ? 208.312 170.171 132.898 1.00 40.29  ? 238  SER C O   1 
ATOM   7503  C CB  . SER B 2 220 ? 205.012 169.884 133.352 1.00 53.66  ? 238  SER C CB  1 
ATOM   7504  O OG  . SER B 2 220 ? 205.309 171.204 133.766 1.00 53.66  ? 238  SER C OG  1 
ATOM   7505  N N   . GLU B 2 221 ? 207.101 169.393 131.166 1.00 40.29  ? 239  GLU C N   1 
ATOM   7506  C CA  . GLU B 2 221 ? 207.949 169.953 130.098 1.00 40.29  ? 239  GLU C CA  1 
ATOM   7507  C C   . GLU B 2 221 ? 207.277 170.030 128.715 1.00 40.29  ? 239  GLU C C   1 
ATOM   7508  O O   . GLU B 2 221 ? 206.284 169.355 128.445 1.00 40.29  ? 239  GLU C O   1 
ATOM   7509  C CB  . GLU B 2 221 ? 209.245 169.139 129.981 1.00 53.10  ? 239  GLU C CB  1 
ATOM   7510  C CG  . GLU B 2 221 ? 209.038 167.679 129.557 1.00 53.10  ? 239  GLU C CG  1 
ATOM   7511  C CD  . GLU B 2 221 ? 210.222 166.835 130.036 1.00 53.10  ? 239  GLU C CD  1 
ATOM   7512  O OE1 . GLU B 2 221 ? 211.377 167.149 129.675 1.00 53.10  ? 239  GLU C OE1 1 
ATOM   7513  O OE2 . GLU B 2 221 ? 210.005 165.879 130.810 1.00 53.10  ? 239  GLU C OE2 1 
ATOM   7514  N N   . LYS B 2 222 ? 207.855 170.839 127.820 1.00 43.32  ? 240  LYS C N   1 
ATOM   7515  C CA  . LYS B 2 222 ? 207.581 170.827 126.373 1.00 43.32  ? 240  LYS C CA  1 
ATOM   7516  C C   . LYS B 2 222 ? 208.491 169.846 125.635 1.00 43.32  ? 240  LYS C C   1 
ATOM   7517  O O   . LYS B 2 222 ? 209.582 169.537 126.104 1.00 43.32  ? 240  LYS C O   1 
ATOM   7518  C CB  . LYS B 2 222 ? 207.743 172.222 125.768 1.00 61.96  ? 240  LYS C CB  1 
ATOM   7519  C CG  . LYS B 2 222 ? 206.608 173.160 126.195 1.00 61.96  ? 240  LYS C CG  1 
ATOM   7520  C CD  . LYS B 2 222 ? 206.707 174.518 125.495 1.00 61.96  ? 240  LYS C CD  1 
ATOM   7521  C CE  . LYS B 2 222 ? 206.221 174.423 124.046 1.00 61.96  ? 240  LYS C CE  1 
ATOM   7522  N NZ  . LYS B 2 222 ? 206.743 175.524 123.193 1.00 61.96  ? 240  LYS C NZ  1 
ATOM   7523  N N   . VAL B 2 223 ? 208.069 169.407 124.452 1.00 50.71  ? 241  VAL C N   1 
ATOM   7524  C CA  . VAL B 2 223 ? 208.705 168.309 123.706 1.00 50.71  ? 241  VAL C CA  1 
ATOM   7525  C C   . VAL B 2 223 ? 208.887 168.641 122.228 1.00 50.71  ? 241  VAL C C   1 
ATOM   7526  O O   . VAL B 2 223 ? 207.918 168.687 121.477 1.00 50.71  ? 241  VAL C O   1 
ATOM   7527  C CB  . VAL B 2 223 ? 207.858 167.033 123.887 1.00 71.41  ? 241  VAL C CB  1 
ATOM   7528  C CG1 . VAL B 2 223 ? 208.312 165.826 123.063 1.00 71.41  ? 241  VAL C CG1 1 
ATOM   7529  C CG2 . VAL B 2 223 ? 207.881 166.613 125.356 1.00 71.41  ? 241  VAL C CG2 1 
ATOM   7530  N N   . GLY B 2 224 ? 210.128 168.845 121.787 1.00 63.74  ? 242  GLY C N   1 
ATOM   7531  C CA  . GLY B 2 224 ? 210.450 169.052 120.376 1.00 63.74  ? 242  GLY C CA  1 
ATOM   7532  C C   . GLY B 2 224 ? 210.084 167.864 119.489 1.00 63.74  ? 242  GLY C C   1 
ATOM   7533  O O   . GLY B 2 224 ? 210.324 166.721 119.853 1.00 63.74  ? 242  GLY C O   1 
ATOM   7534  N N   . ARG B 2 225 ? 209.604 168.147 118.280 1.00 77.46  ? 243  ARG C N   1 
ATOM   7535  C CA  . ARG B 2 225 ? 209.653 167.222 117.141 1.00 77.46  ? 243  ARG C CA  1 
ATOM   7536  C C   . ARG B 2 225 ? 211.109 166.965 116.768 1.00 77.46  ? 243  ARG C C   1 
ATOM   7537  O O   . ARG B 2 225 ? 211.522 165.834 116.529 1.00 77.46  ? 243  ARG C O   1 
ATOM   7538  C CB  . ARG B 2 225 ? 208.953 167.855 115.923 1.00 108.79 ? 243  ARG C CB  1 
ATOM   7539  C CG  . ARG B 2 225 ? 207.474 168.217 116.121 1.00 108.79 ? 243  ARG C CG  1 
ATOM   7540  C CD  . ARG B 2 225 ? 207.001 169.230 115.076 1.00 108.79 ? 243  ARG C CD  1 
ATOM   7541  N NE  . ARG B 2 225 ? 207.669 170.527 115.271 1.00 108.79 ? 243  ARG C NE  1 
ATOM   7542  C CZ  . ARG B 2 225 ? 207.587 171.602 114.517 1.00 108.79 ? 243  ARG C CZ  1 
ATOM   7543  N NH1 . ARG B 2 225 ? 208.214 172.685 114.854 1.00 108.79 ? 243  ARG C NH1 1 
ATOM   7544  N NH2 . ARG B 2 225 ? 206.883 171.623 113.429 1.00 108.79 ? 243  ARG C NH2 1 
ATOM   7545  N N   . ALA B 2 226 ? 211.885 168.045 116.722 1.00 96.98  ? 244  ALA C N   1 
ATOM   7546  C CA  . ALA B 2 226 ? 213.247 168.102 116.207 1.00 96.98  ? 244  ALA C CA  1 
ATOM   7547  C C   . ALA B 2 226 ? 214.317 167.714 117.252 1.00 96.98  ? 244  ALA C C   1 
ATOM   7548  O O   . ALA B 2 226 ? 215.256 168.471 117.507 1.00 96.98  ? 244  ALA C O   1 
ATOM   7549  C CB  . ALA B 2 226 ? 213.442 169.504 115.612 1.00 131.02 ? 244  ALA C CB  1 
ATOM   7550  N N   . MET B 2 227 ? 214.180 166.543 117.880 1.00 87.42  ? 245  MET C N   1 
ATOM   7551  C CA  . MET B 2 227 ? 215.117 166.057 118.879 1.00 87.42  ? 245  MET C CA  1 
ATOM   7552  C C   . MET B 2 227 ? 215.276 164.556 118.695 1.00 87.42  ? 245  MET C C   1 
ATOM   7553  O O   . MET B 2 227 ? 214.428 163.913 118.071 1.00 87.42  ? 245  MET C O   1 
ATOM   7554  C CB  . MET B 2 227 ? 214.680 166.438 120.286 1.00 121.62 ? 245  MET C CB  1 
ATOM   7555  C CG  . MET B 2 227 ? 213.413 165.825 120.764 1.00 121.62 ? 245  MET C CG  1 
ATOM   7556  S SD  . MET B 2 227 ? 212.972 166.425 122.394 1.00 121.62 ? 245  MET C SD  1 
ATOM   7557  C CE  . MET B 2 227 ? 211.728 165.284 122.836 1.00 121.62 ? 245  MET C CE  1 
ATOM   7558  N N   . SER B 2 228 ? 216.364 164.007 119.214 1.00 79.56  ? 246  SER C N   1 
ATOM   7559  C CA  . SER B 2 228 ? 216.662 162.590 119.076 1.00 79.56  ? 246  SER C CA  1 
ATOM   7560  C C   . SER B 2 228 ? 215.714 161.715 119.862 1.00 79.56  ? 246  SER C C   1 
ATOM   7561  O O   . SER B 2 228 ? 215.100 162.158 120.834 1.00 79.56  ? 246  SER C O   1 
ATOM   7562  C CB  . SER B 2 228 ? 218.078 162.339 119.538 1.00 105.97 ? 246  SER C CB  1 
ATOM   7563  O OG  . SER B 2 228 ? 218.196 162.553 120.920 1.00 105.97 ? 246  SER C OG  1 
ATOM   7564  N N   . ARG B 2 229 ? 215.668 160.422 119.514 1.00 64.47  ? 247  ARG C N   1 
ATOM   7565  C CA  . ARG B 2 229 ? 214.765 159.517 120.213 1.00 64.47  ? 247  ARG C CA  1 
ATOM   7566  C C   . ARG B 2 229 ? 215.116 159.471 121.690 1.00 64.47  ? 247  ARG C C   1 
ATOM   7567  O O   . ARG B 2 229 ? 214.241 159.295 122.534 1.00 64.47  ? 247  ARG C O   1 
ATOM   7568  C CB  . ARG B 2 229 ? 214.858 158.101 119.672 1.00 90.54  ? 247  ARG C CB  1 
ATOM   7569  C CG  . ARG B 2 229 ? 216.137 157.340 120.030 1.00 90.54  ? 247  ARG C CG  1 
ATOM   7570  C CD  . ARG B 2 229 ? 216.193 156.021 119.397 1.00 90.54  ? 247  ARG C CD  1 
ATOM   7571  N NE  . ARG B 2 229 ? 217.372 155.279 119.838 1.00 90.54  ? 247  ARG C NE  1 
ATOM   7572  C CZ  . ARG B 2 229 ? 218.613 155.373 119.307 1.00 90.54  ? 247  ARG C CZ  1 
ATOM   7573  N NH1 . ARG B 2 229 ? 219.592 154.644 119.817 1.00 90.54  ? 247  ARG C NH1 1 
ATOM   7574  N NH2 . ARG B 2 229 ? 218.856 156.182 118.293 1.00 90.54  ? 247  ARG C NH2 1 
ATOM   7575  N N   . ALA B 2 230 ? 216.400 159.659 121.996 1.00 74.08  ? 248  ALA C N   1 
ATOM   7576  C CA  . ALA B 2 230 ? 216.894 159.660 123.353 1.00 74.08  ? 248  ALA C CA  1 
ATOM   7577  C C   . ALA B 2 230 ? 216.294 160.801 124.150 1.00 74.08  ? 248  ALA C C   1 
ATOM   7578  O O   . ALA B 2 230 ? 216.137 160.695 125.365 1.00 74.08  ? 248  ALA C O   1 
ATOM   7579  C CB  . ALA B 2 230 ? 218.397 159.768 123.357 1.00 100.08 ? 248  ALA C CB  1 
ATOM   7580  N N   . ALA B 2 231 ? 216.024 161.927 123.495 1.00 72.35  ? 249  ALA C N   1 
ATOM   7581  C CA  . ALA B 2 231 ? 215.453 163.062 124.167 1.00 72.35  ? 249  ALA C CA  1 
ATOM   7582  C C   . ALA B 2 231 ? 214.021 162.740 124.559 1.00 72.35  ? 249  ALA C C   1 
ATOM   7583  O O   . ALA B 2 231 ? 213.555 163.166 125.616 1.00 72.35  ? 249  ALA C O   1 
ATOM   7584  C CB  . ALA B 2 231 ? 215.542 164.266 123.283 1.00 97.74  ? 249  ALA C CB  1 
ATOM   7585  N N   . PHE B 2 232 ? 213.345 161.949 123.721 1.00 66.38  ? 250  PHE C N   1 
ATOM   7586  C CA  . PHE B 2 232 ? 211.968 161.538 124.004 1.00 66.38  ? 250  PHE C CA  1 
ATOM   7587  C C   . PHE B 2 232 ? 212.004 160.559 125.164 1.00 66.38  ? 250  PHE C C   1 
ATOM   7588  O O   . PHE B 2 232 ? 211.129 160.575 126.039 1.00 66.38  ? 250  PHE C O   1 
ATOM   7589  C CB  . PHE B 2 232 ? 211.314 160.899 122.784 1.00 89.77  ? 250  PHE C CB  1 
ATOM   7590  C CG  . PHE B 2 232 ? 210.908 161.873 121.734 1.00 89.77  ? 250  PHE C CG  1 
ATOM   7591  C CD1 . PHE B 2 232 ? 211.786 162.280 120.772 1.00 89.77  ? 250  PHE C CD1 1 
ATOM   7592  C CD2 . PHE B 2 232 ? 209.633 162.347 121.685 1.00 89.77  ? 250  PHE C CD2 1 
ATOM   7593  C CE1 . PHE B 2 232 ? 211.402 163.157 119.798 1.00 89.77  ? 250  PHE C CE1 1 
ATOM   7594  C CE2 . PHE B 2 232 ? 209.224 163.229 120.718 1.00 89.77  ? 250  PHE C CE2 1 
ATOM   7595  C CZ  . PHE B 2 232 ? 210.115 163.643 119.769 1.00 89.77  ? 250  PHE C CZ  1 
ATOM   7596  N N   . GLU B 2 233 ? 213.035 159.710 125.182 1.00 69.40  ? 251  GLU C N   1 
ATOM   7597  C CA  . GLU B 2 233 ? 213.205 158.791 126.290 1.00 69.40  ? 251  GLU C CA  1 
ATOM   7598  C C   . GLU B 2 233 ? 213.501 159.590 127.533 1.00 69.40  ? 251  GLU C C   1 
ATOM   7599  O O   . GLU B 2 233 ? 213.004 159.257 128.598 1.00 69.40  ? 251  GLU C O   1 
ATOM   7600  C CB  . GLU B 2 233 ? 214.341 157.807 126.072 1.00 91.46  ? 251  GLU C CB  1 
ATOM   7601  C CG  . GLU B 2 233 ? 214.155 156.781 125.027 1.00 91.46  ? 251  GLU C CG  1 
ATOM   7602  C CD  . GLU B 2 233 ? 215.408 155.943 124.839 1.00 91.46  ? 251  GLU C CD  1 
ATOM   7603  O OE1 . GLU B 2 233 ? 216.444 156.265 125.439 1.00 91.46  ? 251  GLU C OE1 1 
ATOM   7604  O OE2 . GLU B 2 233 ? 215.337 154.989 124.087 1.00 91.46  ? 251  GLU C OE2 1 
ATOM   7605  N N   . GLY B 2 234 ? 214.281 160.666 127.401 1.00 73.56  ? 252  GLY C N   1 
ATOM   7606  C CA  . GLY B 2 234 ? 214.627 161.513 128.524 1.00 73.56  ? 252  GLY C CA  1 
ATOM   7607  C C   . GLY B 2 234 ? 213.381 162.107 129.158 1.00 73.56  ? 252  GLY C C   1 
ATOM   7608  O O   . GLY B 2 234 ? 213.283 162.137 130.387 1.00 73.56  ? 252  GLY C O   1 
ATOM   7609  N N   . VAL B 2 235 ? 212.438 162.558 128.341 1.00 68.83  ? 253  VAL C N   1 
ATOM   7610  C CA  . VAL B 2 235 ? 211.150 163.043 128.824 1.00 68.83  ? 253  VAL C CA  1 
ATOM   7611  C C   . VAL B 2 235 ? 210.453 161.939 129.608 1.00 68.83  ? 253  VAL C C   1 
ATOM   7612  O O   . VAL B 2 235 ? 210.025 162.149 130.744 1.00 68.83  ? 253  VAL C O   1 
ATOM   7613  C CB  . VAL B 2 235 ? 210.298 163.503 127.634 1.00 96.93  ? 253  VAL C CB  1 
ATOM   7614  C CG1 . VAL B 2 235 ? 208.859 163.827 128.018 1.00 96.93  ? 253  VAL C CG1 1 
ATOM   7615  C CG2 . VAL B 2 235 ? 210.895 164.732 126.956 1.00 96.93  ? 253  VAL C CG2 1 
ATOM   7616  N N   . VAL B 2 236 ? 210.382 160.726 129.047 1.00 65.87  ? 254  VAL C N   1 
ATOM   7617  C CA  . VAL B 2 236 ? 209.709 159.656 129.747 1.00 65.87  ? 254  VAL C CA  1 
ATOM   7618  C C   . VAL B 2 236 ? 210.443 159.333 131.040 1.00 65.87  ? 254  VAL C C   1 
ATOM   7619  O O   . VAL B 2 236 ? 209.804 159.075 132.055 1.00 65.87  ? 254  VAL C O   1 
ATOM   7620  C CB  . VAL B 2 236 ? 209.562 158.400 128.878 1.00 92.76  ? 254  VAL C CB  1 
ATOM   7621  C CG1 . VAL B 2 236 ? 208.990 157.245 129.727 1.00 92.76  ? 254  VAL C CG1 1 
ATOM   7622  C CG2 . VAL B 2 236 ? 208.644 158.695 127.687 1.00 92.76  ? 254  VAL C CG2 1 
ATOM   7623  N N   . ARG B 2 237 ? 211.766 159.297 131.019 1.00 68.08  ? 255  ARG C N   1 
ATOM   7624  C CA  . ARG B 2 237 ? 212.471 159.000 132.233 1.00 68.08  ? 255  ARG C CA  1 
ATOM   7625  C C   . ARG B 2 237 ? 212.171 160.068 133.263 1.00 68.08  ? 255  ARG C C   1 
ATOM   7626  O O   . ARG B 2 237 ? 211.892 159.743 134.408 1.00 68.08  ? 255  ARG C O   1 
ATOM   7627  C CB  . ARG B 2 237 ? 213.965 158.900 131.998 1.00 95.61  ? 255  ARG C CB  1 
ATOM   7628  C CG  . ARG B 2 237 ? 214.415 157.667 131.203 1.00 95.61  ? 255  ARG C CG  1 
ATOM   7629  C CD  . ARG B 2 237 ? 215.905 157.565 131.118 1.00 95.61  ? 255  ARG C CD  1 
ATOM   7630  N NE  . ARG B 2 237 ? 216.322 156.433 130.282 1.00 95.61  ? 255  ARG C NE  1 
ATOM   7631  C CZ  . ARG B 2 237 ? 216.663 156.495 128.968 1.00 95.61  ? 255  ARG C CZ  1 
ATOM   7632  N NH1 . ARG B 2 237 ? 216.978 155.401 128.303 1.00 95.61  ? 255  ARG C NH1 1 
ATOM   7633  N NH2 . ARG B 2 237 ? 216.688 157.622 128.312 1.00 95.61  ? 255  ARG C NH2 1 
ATOM   7634  N N   . ALA B 2 238 ? 212.195 161.336 132.878 1.00 66.45  ? 256  ALA C N   1 
ATOM   7635  C CA  . ALA B 2 238 ? 211.944 162.430 133.796 1.00 66.45  ? 256  ALA C CA  1 
ATOM   7636  C C   . ALA B 2 238 ? 210.606 162.262 134.523 1.00 66.45  ? 256  ALA C C   1 
ATOM   7637  O O   . ALA B 2 238 ? 210.552 162.434 135.739 1.00 66.45  ? 256  ALA C O   1 
ATOM   7638  C CB  . ALA B 2 238 ? 212.042 163.744 133.028 1.00 89.77  ? 256  ALA C CB  1 
ATOM   7639  N N   . LEU B 2 239 ? 209.564 161.811 133.823 1.00 58.35  ? 257  LEU C N   1 
ATOM   7640  C CA  . LEU B 2 239 ? 208.316 161.382 134.460 1.00 58.35  ? 257  LEU C CA  1 
ATOM   7641  C C   . LEU B 2 239 ? 208.594 160.274 135.473 1.00 58.35  ? 257  LEU C C   1 
ATOM   7642  O O   . LEU B 2 239 ? 208.309 160.408 136.664 1.00 58.35  ? 257  LEU C O   1 
ATOM   7643  C CB  . LEU B 2 239 ? 207.350 160.891 133.370 1.00 82.94  ? 257  LEU C CB  1 
ATOM   7644  C CG  . LEU B 2 239 ? 205.983 160.318 133.805 1.00 82.94  ? 257  LEU C CG  1 
ATOM   7645  C CD1 . LEU B 2 239 ? 205.237 161.458 134.489 1.00 82.94  ? 257  LEU C CD1 1 
ATOM   7646  C CD2 . LEU B 2 239 ? 205.027 159.796 132.732 1.00 82.94  ? 257  LEU C CD2 1 
ATOM   7647  N N   . LEU B 2 240 ? 209.189 159.180 135.002 1.00 66.88  ? 258  LEU C N   1 
ATOM   7648  C CA  . LEU B 2 240 ? 209.424 158.004 135.825 1.00 66.88  ? 258  LEU C CA  1 
ATOM   7649  C C   . LEU B 2 240 ? 210.396 158.257 136.979 1.00 66.88  ? 258  LEU C C   1 
ATOM   7650  O O   . LEU B 2 240 ? 210.432 157.502 137.950 1.00 66.88  ? 258  LEU C O   1 
ATOM   7651  C CB  . LEU B 2 240 ? 209.999 156.899 134.937 1.00 95.06  ? 258  LEU C CB  1 
ATOM   7652  C CG  . LEU B 2 240 ? 209.098 156.368 133.767 1.00 95.06  ? 258  LEU C CG  1 
ATOM   7653  C CD1 . LEU B 2 240 ? 209.949 155.420 132.937 1.00 95.06  ? 258  LEU C CD1 1 
ATOM   7654  C CD2 . LEU B 2 240 ? 207.817 155.666 134.283 1.00 95.06  ? 258  LEU C CD2 1 
ATOM   7655  N N   . GLN B 2 241 ? 211.162 159.333 136.896 1.00 73.04  ? 259  GLN C N   1 
ATOM   7656  C CA  . GLN B 2 241 ? 212.135 159.691 137.911 1.00 73.04  ? 259  GLN C CA  1 
ATOM   7657  C C   . GLN B 2 241 ? 211.526 160.361 139.126 1.00 73.04  ? 259  GLN C C   1 
ATOM   7658  O O   . GLN B 2 241 ? 212.221 160.551 140.124 1.00 73.04  ? 259  GLN C O   1 
ATOM   7659  C CB  . GLN B 2 241 ? 213.230 160.575 137.329 1.00 99.27  ? 259  GLN C CB  1 
ATOM   7660  C CG  . GLN B 2 241 ? 214.190 159.869 136.380 1.00 99.27  ? 259  GLN C CG  1 
ATOM   7661  C CD  . GLN B 2 241 ? 215.032 160.845 135.631 1.00 99.27  ? 259  GLN C CD  1 
ATOM   7662  O OE1 . GLN B 2 241 ? 214.799 162.053 135.707 1.00 99.27  ? 259  GLN C OE1 1 
ATOM   7663  N NE2 . GLN B 2 241 ? 216.011 160.349 134.895 1.00 99.27  ? 259  GLN C NE2 1 
ATOM   7664  N N   . LYS B 2 242 ? 210.240 160.736 139.070 1.00 67.91  ? 260  LYS C N   1 
ATOM   7665  C CA  . LYS B 2 242 ? 209.512 161.368 140.181 1.00 67.91  ? 260  LYS C CA  1 
ATOM   7666  C C   . LYS B 2 242 ? 208.244 160.587 140.545 1.00 67.91  ? 260  LYS C C   1 
ATOM   7667  O O   . LYS B 2 242 ? 207.133 161.096 140.394 1.00 67.91  ? 260  LYS C O   1 
ATOM   7668  C CB  . LYS B 2 242 ? 209.270 162.843 139.835 1.00 97.14  ? 260  LYS C CB  1 
ATOM   7669  C CG  . LYS B 2 242 ? 208.927 163.642 141.098 1.00 97.14  ? 260  LYS C CG  1 
ATOM   7670  C CD  . LYS B 2 242 ? 208.801 165.132 140.784 1.00 97.14  ? 260  LYS C CD  1 
ATOM   7671  C CE  . LYS B 2 242 ? 208.655 165.933 142.079 1.00 97.14  ? 260  LYS C CE  1 
ATOM   7672  N NZ  . LYS B 2 242 ? 208.633 167.391 141.830 1.00 97.14  ? 260  LYS C NZ  1 
ATOM   7673  N N   . PRO B 2 243 ? 208.375 159.334 141.007 1.00 74.76  ? 261  PRO C N   1 
ATOM   7674  C CA  . PRO B 2 243 ? 207.231 158.474 141.194 1.00 74.76  ? 261  PRO C CA  1 
ATOM   7675  C C   . PRO B 2 243 ? 206.505 158.716 142.500 1.00 74.76  ? 261  PRO C C   1 
ATOM   7676  O O   . PRO B 2 243 ? 206.430 157.830 143.344 1.00 74.76  ? 261  PRO C O   1 
ATOM   7677  C CB  . PRO B 2 243 ? 207.869 157.094 141.202 1.00 127.75 ? 261  PRO C CB  1 
ATOM   7678  C CG  . PRO B 2 243 ? 209.203 157.325 141.839 1.00 127.75 ? 261  PRO C CG  1 
ATOM   7679  C CD  . PRO B 2 243 ? 209.653 158.665 141.316 1.00 127.75 ? 261  PRO C CD  1 
ATOM   7680  N N   . SER B 2 244 ? 206.001 159.928 142.694 1.00 66.84  ? 262  SER C N   1 
ATOM   7681  C CA  . SER B 2 244 ? 205.203 160.208 143.889 1.00 66.84  ? 262  SER C CA  1 
ATOM   7682  C C   . SER B 2 244 ? 203.777 159.835 143.520 1.00 66.84  ? 262  SER C C   1 
ATOM   7683  O O   . SER B 2 244 ? 202.899 159.628 144.352 1.00 66.84  ? 262  SER C O   1 
ATOM   7684  C CB  . SER B 2 244 ? 205.316 161.657 144.303 1.00 89.03  ? 262  SER C CB  1 
ATOM   7685  O OG  . SER B 2 244 ? 206.615 161.986 144.704 1.00 89.03  ? 262  SER C OG  1 
ATOM   7686  N N   . ALA B 2 245 ? 203.495 159.908 142.223 1.00 62.44  ? 263  ALA C N   1 
ATOM   7687  C CA  . ALA B 2 245 ? 202.384 159.367 141.484 1.00 62.44  ? 263  ALA C CA  1 
ATOM   7688  C C   . ALA B 2 245 ? 203.018 158.843 140.191 1.00 62.44  ? 263  ALA C C   1 
ATOM   7689  O O   . ALA B 2 245 ? 204.073 159.325 139.771 1.00 62.44  ? 263  ALA C O   1 
ATOM   7690  C CB  . ALA B 2 245 ? 201.351 160.463 141.249 1.00 84.35  ? 263  ALA C CB  1 
ATOM   7691  N N   . ARG B 2 246 ? 202.444 157.801 139.603 1.00 47.89  ? 264  ARG C N   1 
ATOM   7692  C CA  . ARG B 2 246 ? 203.077 157.072 138.491 1.00 47.89  ? 264  ARG C CA  1 
ATOM   7693  C C   . ARG B 2 246 ? 202.179 157.130 137.267 1.00 47.89  ? 264  ARG C C   1 
ATOM   7694  O O   . ARG B 2 246 ? 201.696 156.118 136.772 1.00 47.89  ? 264  ARG C O   1 
ATOM   7695  C CB  . ARG B 2 246 ? 203.461 155.649 138.911 1.00 67.26  ? 264  ARG C CB  1 
ATOM   7696  C CG  . ARG B 2 246 ? 204.597 155.588 139.941 1.00 67.26  ? 264  ARG C CG  1 
ATOM   7697  C CD  . ARG B 2 246 ? 204.162 155.887 141.375 1.00 67.26  ? 264  ARG C CD  1 
ATOM   7698  N NE  . ARG B 2 246 ? 205.059 155.240 142.336 1.00 67.26  ? 264  ARG C NE  1 
ATOM   7699  C CZ  . ARG B 2 246 ? 205.039 155.314 143.652 1.00 67.26  ? 264  ARG C CZ  1 
ATOM   7700  N NH1 . ARG B 2 246 ? 205.936 154.688 144.348 1.00 67.26  ? 264  ARG C NH1 1 
ATOM   7701  N NH2 . ARG B 2 246 ? 204.144 155.992 144.305 1.00 67.26  ? 264  ARG C NH2 1 
ATOM   7702  N N   . VAL B 2 247 ? 201.872 158.356 136.882 1.00 40.29  ? 265  VAL C N   1 
ATOM   7703  C CA  . VAL B 2 247 ? 200.820 158.687 135.936 1.00 40.29  ? 265  VAL C CA  1 
ATOM   7704  C C   . VAL B 2 247 ? 201.090 160.071 135.339 1.00 40.29  ? 265  VAL C C   1 
ATOM   7705  O O   . VAL B 2 247 ? 201.750 160.891 135.982 1.00 40.29  ? 265  VAL C O   1 
ATOM   7706  C CB  . VAL B 2 247 ? 199.442 158.649 136.631 1.00 56.74  ? 265  VAL C CB  1 
ATOM   7707  C CG1 . VAL B 2 247 ? 198.985 157.268 137.100 1.00 56.74  ? 265  VAL C CG1 1 
ATOM   7708  C CG2 . VAL B 2 247 ? 199.370 159.553 137.865 1.00 56.74  ? 265  VAL C CG2 1 
ATOM   7709  N N   . ALA B 2 248 ? 200.586 160.361 134.135 1.00 40.29  ? 266  ALA C N   1 
ATOM   7710  C CA  . ALA B 2 248 ? 200.862 161.642 133.472 1.00 40.29  ? 266  ALA C CA  1 
ATOM   7711  C C   . ALA B 2 248 ? 199.849 162.093 132.402 1.00 40.29  ? 266  ALA C C   1 
ATOM   7712  O O   . ALA B 2 248 ? 198.978 161.332 132.000 1.00 40.29  ? 266  ALA C O   1 
ATOM   7713  C CB  . ALA B 2 248 ? 202.268 161.578 132.870 1.00 54.43  ? 266  ALA C CB  1 
ATOM   7714  N N   . VAL B 2 249 ? 199.946 163.329 131.902 1.00 40.29  ? 267  VAL C N   1 
ATOM   7715  C CA  . VAL B 2 249 ? 199.025 163.855 130.872 1.00 40.29  ? 267  VAL C CA  1 
ATOM   7716  C C   . VAL B 2 249 ? 199.740 164.704 129.828 1.00 40.29  ? 267  VAL C C   1 
ATOM   7717  O O   . VAL B 2 249 ? 200.738 165.351 130.130 1.00 40.29  ? 267  VAL C O   1 
ATOM   7718  C CB  . VAL B 2 249 ? 197.860 164.648 131.492 1.00 56.74  ? 267  VAL C CB  1 
ATOM   7719  C CG1 . VAL B 2 249 ? 196.785 165.005 130.456 1.00 56.74  ? 267  VAL C CG1 1 
ATOM   7720  C CG2 . VAL B 2 249 ? 197.156 163.878 132.614 1.00 56.74  ? 267  VAL C CG2 1 
ATOM   7721  N N   . LEU B 2 250 ? 199.253 164.679 128.594 1.00 40.29  ? 268  LEU C N   1 
ATOM   7722  C CA  . LEU B 2 250 ? 199.921 165.209 127.429 1.00 40.29  ? 268  LEU C CA  1 
ATOM   7723  C C   . LEU B 2 250 ? 199.046 166.153 126.592 1.00 40.29  ? 268  LEU C C   1 
ATOM   7724  O O   . LEU B 2 250 ? 197.974 165.782 126.141 1.00 40.29  ? 268  LEU C O   1 
ATOM   7725  C CB  . LEU B 2 250 ? 200.355 163.979 126.631 1.00 57.27  ? 268  LEU C CB  1 
ATOM   7726  C CG  . LEU B 2 250 ? 200.991 164.332 125.290 1.00 57.27  ? 268  LEU C CG  1 
ATOM   7727  C CD1 . LEU B 2 250 ? 202.303 165.082 125.482 1.00 57.27  ? 268  LEU C CD1 1 
ATOM   7728  C CD2 . LEU B 2 250 ? 201.265 163.056 124.500 1.00 57.27  ? 268  LEU C CD2 1 
ATOM   7729  N N   . PHE B 2 251 ? 199.588 167.312 126.248 1.00 40.29  ? 269  PHE C N   1 
ATOM   7730  C CA  . PHE B 2 251 ? 199.228 168.114 125.088 1.00 40.29  ? 269  PHE C CA  1 
ATOM   7731  C C   . PHE B 2 251 ? 200.247 167.878 123.989 1.00 40.29  ? 269  PHE C C   1 
ATOM   7732  O O   . PHE B 2 251 ? 201.442 167.817 124.242 1.00 40.29  ? 269  PHE C O   1 
ATOM   7733  C CB  . PHE B 2 251 ? 199.190 169.601 125.434 1.00 54.49  ? 269  PHE C CB  1 
ATOM   7734  C CG  . PHE B 2 251 ? 197.808 170.070 125.816 1.00 54.49  ? 269  PHE C CG  1 
ATOM   7735  C CD1 . PHE B 2 251 ? 196.849 170.309 124.816 1.00 54.49  ? 269  PHE C CD1 1 
ATOM   7736  C CD2 . PHE B 2 251 ? 197.473 170.266 127.164 1.00 54.49  ? 269  PHE C CD2 1 
ATOM   7737  C CE1 . PHE B 2 251 ? 195.566 170.759 125.168 1.00 54.49  ? 269  PHE C CE1 1 
ATOM   7738  C CE2 . PHE B 2 251 ? 196.192 170.727 127.510 1.00 54.49  ? 269  PHE C CE2 1 
ATOM   7739  C CZ  . PHE B 2 251 ? 195.239 170.987 126.514 1.00 54.49  ? 269  PHE C CZ  1 
ATOM   7740  N N   . THR B 2 252 ? 199.809 167.712 122.750 1.00 40.29  ? 270  THR C N   1 
ATOM   7741  C CA  . THR B 2 252 ? 200.707 167.213 121.707 1.00 40.29  ? 270  THR C CA  1 
ATOM   7742  C C   . THR B 2 252 ? 200.181 167.464 120.313 1.00 40.29  ? 270  THR C C   1 
ATOM   7743  O O   . THR B 2 252 ? 199.051 167.916 120.149 1.00 40.29  ? 270  THR C O   1 
ATOM   7744  C CB  . THR B 2 252 ? 200.897 165.709 121.915 1.00 55.15  ? 270  THR C CB  1 
ATOM   7745  O OG1 . THR B 2 252 ? 201.974 165.214 121.173 1.00 55.15  ? 270  THR C OG1 1 
ATOM   7746  C CG2 . THR B 2 252 ? 199.665 164.883 121.543 1.00 55.15  ? 270  THR C CG2 1 
ATOM   7747  N N   . ARG B 2 253 ? 200.986 167.131 119.312 1.00 40.29  ? 271  ARG C N   1 
ATOM   7748  C CA  . ARG B 2 253 ? 200.498 166.724 117.999 1.00 40.29  ? 271  ARG C CA  1 
ATOM   7749  C C   . ARG B 2 253 ? 201.151 165.385 117.668 1.00 40.29  ? 271  ARG C C   1 
ATOM   7750  O O   . ARG B 2 253 ? 202.211 165.043 118.185 1.00 40.29  ? 271  ARG C O   1 
ATOM   7751  C CB  . ARG B 2 253 ? 200.698 167.808 116.940 1.00 55.75  ? 271  ARG C CB  1 
ATOM   7752  C CG  . ARG B 2 253 ? 199.856 169.065 117.207 1.00 55.75  ? 271  ARG C CG  1 
ATOM   7753  C CD  . ARG B 2 253 ? 198.339 168.853 117.139 1.00 55.75  ? 271  ARG C CD  1 
ATOM   7754  N NE  . ARG B 2 253 ? 197.616 170.123 117.355 1.00 55.75  ? 271  ARG C NE  1 
ATOM   7755  C CZ  . ARG B 2 253 ? 197.198 170.668 118.484 1.00 55.75  ? 271  ARG C CZ  1 
ATOM   7756  N NH1 . ARG B 2 253 ? 196.603 171.817 118.470 1.00 55.75  ? 271  ARG C NH1 1 
ATOM   7757  N NH2 . ARG B 2 253 ? 197.339 170.138 119.663 1.00 55.75  ? 271  ARG C NH2 1 
ATOM   7758  N N   . SER B 2 254 ? 200.421 164.564 116.928 1.00 40.29  ? 272  SER C N   1 
ATOM   7759  C CA  . SER B 2 254 ? 200.595 163.111 116.921 1.00 40.29  ? 272  SER C CA  1 
ATOM   7760  C C   . SER B 2 254 ? 201.998 162.623 116.557 1.00 40.29  ? 272  SER C C   1 
ATOM   7761  O O   . SER B 2 254 ? 202.418 161.570 117.021 1.00 40.29  ? 272  SER C O   1 
ATOM   7762  C CB  . SER B 2 254 ? 199.584 162.516 115.947 1.00 53.66  ? 272  SER C CB  1 
ATOM   7763  O OG  . SER B 2 254 ? 199.854 162.938 114.624 1.00 53.66  ? 272  SER C OG  1 
ATOM   7764  N N   . GLU B 2 255 ? 202.745 163.381 115.765 1.00 40.29  ? 273  GLU C N   1 
ATOM   7765  C CA  . GLU B 2 255 ? 204.130 163.108 115.414 1.00 40.29  ? 273  GLU C CA  1 
ATOM   7766  C C   . GLU B 2 255 ? 205.021 163.022 116.652 1.00 40.29  ? 273  GLU C C   1 
ATOM   7767  O O   . GLU B 2 255 ? 205.950 162.219 116.712 1.00 40.29  ? 273  GLU C O   1 
ATOM   7768  C CB  . GLU B 2 255 ? 204.623 164.184 114.428 1.00 54.07  ? 273  GLU C CB  1 
ATOM   7769  C CG  . GLU B 2 255 ? 204.813 165.623 114.953 1.00 54.07  ? 273  GLU C CG  1 
ATOM   7770  C CD  . GLU B 2 255 ? 203.550 166.498 115.031 1.00 54.07  ? 273  GLU C CD  1 
ATOM   7771  O OE1 . GLU B 2 255 ? 202.423 165.966 115.069 1.00 54.07  ? 273  GLU C OE1 1 
ATOM   7772  O OE2 . GLU B 2 255 ? 203.687 167.741 115.000 1.00 54.07  ? 273  GLU C OE2 1 
ATOM   7773  N N   . ASP B 2 256 ? 204.701 163.807 117.674 1.00 43.33  ? 274  ASP C N   1 
ATOM   7774  C CA  . ASP B 2 256 ? 205.374 163.745 118.954 1.00 43.33  ? 274  ASP C CA  1 
ATOM   7775  C C   . ASP B 2 256 ? 204.817 162.583 119.759 1.00 43.33  ? 274  ASP C C   1 
ATOM   7776  O O   . ASP B 2 256 ? 205.576 161.775 120.287 1.00 43.33  ? 274  ASP C O   1 
ATOM   7777  C CB  . ASP B 2 256 ? 205.176 165.061 119.705 1.00 55.18  ? 274  ASP C CB  1 
ATOM   7778  C CG  . ASP B 2 256 ? 205.640 166.278 118.910 1.00 55.18  ? 274  ASP C CG  1 
ATOM   7779  O OD1 . ASP B 2 256 ? 206.669 166.157 118.224 1.00 55.18  ? 274  ASP C OD1 1 
ATOM   7780  O OD2 . ASP B 2 256 ? 204.987 167.338 119.018 1.00 55.18  ? 274  ASP C OD2 1 
ATOM   7781  N N   . ALA B 2 257 ? 203.489 162.460 119.814 1.00 40.29  ? 275  ALA C N   1 
ATOM   7782  C CA  . ALA B 2 257 ? 202.831 161.387 120.551 1.00 40.29  ? 275  ALA C CA  1 
ATOM   7783  C C   . ALA B 2 257 ? 203.356 160.013 120.129 1.00 40.29  ? 275  ALA C C   1 
ATOM   7784  O O   . ALA B 2 257 ? 203.595 159.155 120.969 1.00 40.29  ? 275  ALA C O   1 
ATOM   7785  C CB  . ALA B 2 257 ? 201.325 161.493 120.334 1.00 54.43  ? 275  ALA C CB  1 
ATOM   7786  N N   . ARG B 2 258 ? 203.623 159.840 118.838 1.00 41.55  ? 276  ARG C N   1 
ATOM   7787  C CA  . ARG B 2 258 ? 204.296 158.675 118.293 1.00 41.55  ? 276  ARG C CA  1 
ATOM   7788  C C   . ARG B 2 258 ? 205.606 158.400 118.990 1.00 41.55  ? 276  ARG C C   1 
ATOM   7789  O O   . ARG B 2 258 ? 205.774 157.326 119.551 1.00 41.55  ? 276  ARG C O   1 
ATOM   7790  C CB  . ARG B 2 258 ? 204.501 158.922 116.806 1.00 58.36  ? 276  ARG C CB  1 
ATOM   7791  C CG  . ARG B 2 258 ? 205.355 157.832 116.149 1.00 58.36  ? 276  ARG C CG  1 
ATOM   7792  C CD  . ARG B 2 258 ? 205.462 158.057 114.640 1.00 58.36  ? 276  ARG C CD  1 
ATOM   7793  N NE  . ARG B 2 258 ? 204.143 158.235 114.005 1.00 58.36  ? 276  ARG C NE  1 
ATOM   7794  C CZ  . ARG B 2 258 ? 203.149 157.373 113.982 1.00 58.36  ? 276  ARG C CZ  1 
ATOM   7795  N NH1 . ARG B 2 258 ? 201.993 157.725 113.522 1.00 58.36  ? 276  ARG C NH1 1 
ATOM   7796  N NH2 . ARG B 2 258 ? 203.261 156.157 114.425 1.00 58.36  ? 276  ARG C NH2 1 
ATOM   7797  N N   . GLU B 2 259 ? 206.557 159.324 118.933 1.00 46.70  ? 277  GLU C N   1 
ATOM   7798  C CA  . GLU B 2 259 ? 207.881 159.009 119.447 1.00 46.70  ? 277  GLU C CA  1 
ATOM   7799  C C   . GLU B 2 259 ? 207.895 158.947 120.970 1.00 46.70  ? 277  GLU C C   1 
ATOM   7800  O O   . GLU B 2 259 ? 208.578 158.115 121.559 1.00 46.70  ? 277  GLU C O   1 
ATOM   7801  C CB  . GLU B 2 259 ? 208.926 159.986 118.912 1.00 61.55  ? 277  GLU C CB  1 
ATOM   7802  C CG  . GLU B 2 259 ? 210.346 159.566 119.331 1.00 61.55  ? 277  GLU C CG  1 
ATOM   7803  C CD  . GLU B 2 259 ? 210.684 158.108 118.975 1.00 61.55  ? 277  GLU C CD  1 
ATOM   7804  O OE1 . GLU B 2 259 ? 210.258 157.646 117.892 1.00 61.55  ? 277  GLU C OE1 1 
ATOM   7805  O OE2 . GLU B 2 259 ? 211.383 157.426 119.760 1.00 61.55  ? 277  GLU C OE2 1 
ATOM   7806  N N   . LEU B 2 260 ? 207.066 159.750 121.621 1.00 40.29  ? 278  LEU C N   1 
ATOM   7807  C CA  . LEU B 2 260 ? 206.818 159.598 123.042 1.00 40.29  ? 278  LEU C CA  1 
ATOM   7808  C C   . LEU B 2 260 ? 206.307 158.202 123.358 1.00 40.29  ? 278  LEU C C   1 
ATOM   7809  O O   . LEU B 2 260 ? 206.829 157.520 124.239 1.00 40.29  ? 278  LEU C O   1 
ATOM   7810  C CB  . LEU B 2 260 ? 205.774 160.628 123.463 1.00 57.27  ? 278  LEU C CB  1 
ATOM   7811  C CG  . LEU B 2 260 ? 206.302 162.063 123.437 1.00 57.27  ? 278  LEU C CG  1 
ATOM   7812  C CD1 . LEU B 2 260 ? 205.135 163.036 123.566 1.00 57.27  ? 278  LEU C CD1 1 
ATOM   7813  C CD2 . LEU B 2 260 ? 207.278 162.293 124.593 1.00 57.27  ? 278  LEU C CD2 1 
ATOM   7814  N N   . LEU B 2 261 ? 205.297 157.723 122.646 1.00 40.29  ? 279  LEU C N   1 
ATOM   7815  C CA  . LEU B 2 261 ? 204.759 156.404 122.912 1.00 40.29  ? 279  LEU C CA  1 
ATOM   7816  C C   . LEU B 2 261 ? 205.765 155.306 122.543 1.00 40.29  ? 279  LEU C C   1 
ATOM   7817  O O   . LEU B 2 261 ? 205.854 154.271 123.212 1.00 40.29  ? 279  LEU C O   1 
ATOM   7818  C CB  . LEU B 2 261 ? 203.435 156.278 122.164 1.00 57.27  ? 279  LEU C CB  1 
ATOM   7819  C CG  . LEU B 2 261 ? 202.790 154.914 122.380 1.00 57.27  ? 279  LEU C CG  1 
ATOM   7820  C CD1 . LEU B 2 261 ? 202.406 154.637 123.829 1.00 57.27  ? 279  LEU C CD1 1 
ATOM   7821  C CD2 . LEU B 2 261 ? 201.545 154.792 121.520 1.00 57.27  ? 279  LEU C CD2 1 
ATOM   7822  N N   . ALA B 2 262 ? 206.574 155.527 121.513 1.00 48.95  ? 280  ALA C N   1 
ATOM   7823  C CA  . ALA B 2 262 ? 207.666 154.615 121.215 1.00 48.95  ? 280  ALA C CA  1 
ATOM   7824  C C   . ALA B 2 262 ? 208.692 154.575 122.355 1.00 48.95  ? 280  ALA C C   1 
ATOM   7825  O O   . ALA B 2 262 ? 209.092 153.488 122.766 1.00 48.95  ? 280  ALA C O   1 
ATOM   7826  C CB  . ALA B 2 262 ? 208.293 155.016 119.883 1.00 66.13  ? 280  ALA C CB  1 
ATOM   7827  N N   . ALA B 2 263 ? 209.061 155.721 122.937 1.00 51.43  ? 281  ALA C N   1 
ATOM   7828  C CA  . ALA B 2 263 ? 210.002 155.753 124.033 1.00 51.43  ? 281  ALA C CA  1 
ATOM   7829  C C   . ALA B 2 263 ? 209.438 155.028 125.243 1.00 51.43  ? 281  ALA C C   1 
ATOM   7830  O O   . ALA B 2 263 ? 210.125 154.199 125.840 1.00 51.43  ? 281  ALA C O   1 
ATOM   7831  C CB  . ALA B 2 263 ? 210.326 157.182 124.393 1.00 69.48  ? 281  ALA C CB  1 
ATOM   7832  N N   . SER B 2 264 ? 208.166 155.283 125.560 1.00 47.12  ? 282  SER C N   1 
ATOM   7833  C CA  . SER B 2 264 ? 207.429 154.594 126.620 1.00 47.12  ? 282  SER C CA  1 
ATOM   7834  C C   . SER B 2 264 ? 207.529 153.079 126.460 1.00 47.12  ? 282  SER C C   1 
ATOM   7835  O O   . SER B 2 264 ? 207.896 152.357 127.387 1.00 47.12  ? 282  SER C O   1 
ATOM   7836  C CB  . SER B 2 264 ? 205.966 155.046 126.575 1.00 62.76  ? 282  SER C CB  1 
ATOM   7837  O OG  . SER B 2 264 ? 205.151 154.218 127.375 1.00 62.76  ? 282  SER C OG  1 
ATOM   7838  N N   . GLN B 2 265 ? 207.302 152.600 125.242 1.00 51.95  ? 283  GLN C N   1 
ATOM   7839  C CA  . GLN B 2 265 ? 207.329 151.181 124.975 1.00 51.95  ? 283  GLN C CA  1 
ATOM   7840  C C   . GLN B 2 265 ? 208.751 150.626 125.086 1.00 51.95  ? 283  GLN C C   1 
ATOM   7841  O O   . GLN B 2 265 ? 208.964 149.593 125.716 1.00 51.95  ? 283  GLN C O   1 
ATOM   7842  C CB  . GLN B 2 265 ? 206.810 150.924 123.565 1.00 70.61  ? 283  GLN C CB  1 
ATOM   7843  C CG  . GLN B 2 265 ? 206.575 149.456 123.181 1.00 70.61  ? 283  GLN C CG  1 
ATOM   7844  C CD  . GLN B 2 265 ? 205.406 148.814 123.924 1.00 70.61  ? 283  GLN C CD  1 
ATOM   7845  O OE1 . GLN B 2 265 ? 204.253 149.224 123.738 1.00 70.61  ? 283  GLN C OE1 1 
ATOM   7846  N NE2 . GLN B 2 265 ? 205.691 147.834 124.761 1.00 70.61  ? 283  GLN C NE2 1 
ATOM   7847  N N   . ARG B 2 266 ? 209.749 151.348 124.559 1.00 56.77  ? 284  ARG C N   1 
ATOM   7848  C CA  . ARG B 2 266 ? 211.138 150.877 124.588 1.00 56.77  ? 284  ARG C CA  1 
ATOM   7849  C C   . ARG B 2 266 ? 211.693 150.762 125.981 1.00 56.77  ? 284  ARG C C   1 
ATOM   7850  O O   . ARG B 2 266 ? 212.449 149.844 126.297 1.00 56.77  ? 284  ARG C O   1 
ATOM   7851  C CB  . ARG B 2 266 ? 212.081 151.795 123.833 1.00 79.73  ? 284  ARG C CB  1 
ATOM   7852  C CG  . ARG B 2 266 ? 212.008 151.760 122.340 1.00 79.73  ? 284  ARG C CG  1 
ATOM   7853  C CD  . ARG B 2 266 ? 213.189 152.455 121.752 1.00 79.73  ? 284  ARG C CD  1 
ATOM   7854  N NE  . ARG B 2 266 ? 213.222 153.887 122.074 1.00 79.73  ? 284  ARG C NE  1 
ATOM   7855  C CZ  . ARG B 2 266 ? 212.628 154.859 121.353 1.00 79.73  ? 284  ARG C CZ  1 
ATOM   7856  N NH1 . ARG B 2 266 ? 212.740 156.099 121.734 1.00 79.73  ? 284  ARG C NH1 1 
ATOM   7857  N NH2 . ARG B 2 266 ? 211.945 154.606 120.259 1.00 79.73  ? 284  ARG C NH2 1 
ATOM   7858  N N   . LEU B 2 267 ? 211.294 151.687 126.824 1.00 58.21  ? 285  LEU C N   1 
ATOM   7859  C CA  . LEU B 2 267 ? 211.760 151.760 128.187 1.00 58.21  ? 285  LEU C CA  1 
ATOM   7860  C C   . LEU B 2 267 ? 210.972 150.867 129.117 1.00 58.21  ? 285  LEU C C   1 
ATOM   7861  O O   . LEU B 2 267 ? 211.252 150.843 130.316 1.00 58.21  ? 285  LEU C O   1 
ATOM   7862  C CB  . LEU B 2 267 ? 211.614 153.201 128.691 1.00 82.74  ? 285  LEU C CB  1 
ATOM   7863  C CG  . LEU B 2 267 ? 212.461 154.297 127.988 1.00 82.74  ? 285  LEU C CG  1 
ATOM   7864  C CD1 . LEU B 2 267 ? 212.017 155.647 128.513 1.00 82.74  ? 285  LEU C CD1 1 
ATOM   7865  C CD2 . LEU B 2 267 ? 213.922 154.101 128.248 1.00 82.74  ? 285  LEU C CD2 1 
ATOM   7866  N N   . ASN B 2 268 ? 209.946 150.177 128.603 1.00 60.04  ? 286  ASN C N   1 
ATOM   7867  C CA  . ASN B 2 268 ? 209.073 149.370 129.434 1.00 60.04  ? 286  ASN C CA  1 
ATOM   7868  C C   . ASN B 2 268 ? 208.514 150.248 130.540 1.00 60.04  ? 286  ASN C C   1 
ATOM   7869  O O   . ASN B 2 268 ? 208.439 149.839 131.703 1.00 60.04  ? 286  ASN C O   1 
ATOM   7870  C CB  . ASN B 2 268 ? 209.811 148.174 130.011 1.00 79.86  ? 286  ASN C CB  1 
ATOM   7871  C CG  . ASN B 2 268 ? 210.309 147.247 128.956 1.00 79.86  ? 286  ASN C CG  1 
ATOM   7872  O OD1 . ASN B 2 268 ? 209.600 146.919 127.997 1.00 79.86  ? 286  ASN C OD1 1 
ATOM   7873  N ND2 . ASN B 2 268 ? 211.532 146.807 129.110 1.00 79.86  ? 286  ASN C ND2 1 
ATOM   7874  N N   . ALA B 2 269 ? 208.081 151.462 130.188 1.00 52.10  ? 287  ALA C N   1 
ATOM   7875  C CA  . ALA B 2 269 ? 207.591 152.468 131.121 1.00 52.10  ? 287  ALA C CA  1 
ATOM   7876  C C   . ALA B 2 269 ? 206.287 152.044 131.819 1.00 52.10  ? 287  ALA C C   1 
ATOM   7877  O O   . ALA B 2 269 ? 205.297 151.714 131.166 1.00 52.10  ? 287  ALA C O   1 
ATOM   7878  C CB  . ALA B 2 269 ? 207.414 153.778 130.350 1.00 70.38  ? 287  ALA C CB  1 
ATOM   7879  N N   . SER B 2 270 ? 206.279 152.090 133.152 1.00 46.45  ? 288  SER C N   1 
ATOM   7880  C CA  . SER B 2 270 ? 205.128 151.723 133.975 1.00 46.45  ? 288  SER C CA  1 
ATOM   7881  C C   . SER B 2 270 ? 204.433 152.960 134.537 1.00 46.45  ? 288  SER C C   1 
ATOM   7882  O O   . SER B 2 270 ? 204.874 153.570 135.509 1.00 46.45  ? 288  SER C O   1 
ATOM   7883  C CB  . SER B 2 270 ? 205.565 150.771 135.081 1.00 61.87  ? 288  SER C CB  1 
ATOM   7884  O OG  . SER B 2 270 ? 204.424 150.371 135.812 1.00 61.87  ? 288  SER C OG  1 
ATOM   7885  N N   . PHE B 2 271 ? 203.347 153.346 133.884 1.00 40.29  ? 289  PHE C N   1 
ATOM   7886  C CA  . PHE B 2 271 ? 202.473 154.443 134.267 1.00 40.29  ? 289  PHE C CA  1 
ATOM   7887  C C   . PHE B 2 271 ? 201.157 154.321 133.503 1.00 40.29  ? 289  PHE C C   1 
ATOM   7888  O O   . PHE B 2 271 ? 201.013 153.465 132.633 1.00 40.29  ? 289  PHE C O   1 
ATOM   7889  C CB  . PHE B 2 271 ? 203.151 155.805 134.021 1.00 54.49  ? 289  PHE C CB  1 
ATOM   7890  C CG  . PHE B 2 271 ? 203.357 156.228 132.587 1.00 54.49  ? 289  PHE C CG  1 
ATOM   7891  C CD1 . PHE B 2 271 ? 204.166 155.468 131.723 1.00 54.49  ? 289  PHE C CD1 1 
ATOM   7892  C CD2 . PHE B 2 271 ? 202.811 157.439 132.136 1.00 54.49  ? 289  PHE C CD2 1 
ATOM   7893  C CE1 . PHE B 2 271 ? 204.400 155.905 130.412 1.00 54.49  ? 289  PHE C CE1 1 
ATOM   7894  C CE2 . PHE B 2 271 ? 203.083 157.893 130.834 1.00 54.49  ? 289  PHE C CE2 1 
ATOM   7895  C CZ  . PHE B 2 271 ? 203.860 157.117 129.964 1.00 54.49  ? 289  PHE C CZ  1 
ATOM   7896  N N   . THR B 2 272 ? 200.189 155.169 133.804 1.00 40.29  ? 290  THR C N   1 
ATOM   7897  C CA  . THR B 2 272 ? 199.028 155.388 132.930 1.00 40.29  ? 290  THR C CA  1 
ATOM   7898  C C   . THR B 2 272 ? 198.945 156.860 132.569 1.00 40.29  ? 290  THR C C   1 
ATOM   7899  O O   . THR B 2 272 ? 199.399 157.709 133.339 1.00 40.29  ? 290  THR C O   1 
ATOM   7900  C CB  . THR B 2 272 ? 197.714 154.882 133.541 1.00 55.15  ? 290  THR C CB  1 
ATOM   7901  O OG1 . THR B 2 272 ? 197.482 155.445 134.806 1.00 55.15  ? 290  THR C OG1 1 
ATOM   7902  C CG2 . THR B 2 272 ? 197.713 153.372 133.708 1.00 55.15  ? 290  THR C CG2 1 
ATOM   7903  N N   . TRP B 2 273 ? 198.410 157.203 131.405 1.00 40.29  ? 291  TRP C N   1 
ATOM   7904  C CA  . TRP B 2 273 ? 198.460 158.582 130.943 1.00 40.29  ? 291  TRP C CA  1 
ATOM   7905  C C   . TRP B 2 273 ? 197.353 158.984 129.984 1.00 40.29  ? 291  TRP C C   1 
ATOM   7906  O O   . TRP B 2 273 ? 196.633 158.154 129.462 1.00 40.29  ? 291  TRP C O   1 
ATOM   7907  C CB  . TRP B 2 273 ? 199.827 158.844 130.330 1.00 53.94  ? 291  TRP C CB  1 
ATOM   7908  C CG  . TRP B 2 273 ? 200.148 157.979 129.164 1.00 53.94  ? 291  TRP C CG  1 
ATOM   7909  C CD1 . TRP B 2 273 ? 199.982 158.339 127.876 1.00 53.94  ? 291  TRP C CD1 1 
ATOM   7910  C CD2 . TRP B 2 273 ? 200.660 156.613 129.133 1.00 53.94  ? 291  TRP C CD2 1 
ATOM   7911  N NE1 . TRP B 2 273 ? 200.375 157.306 127.055 1.00 53.94  ? 291  TRP C NE1 1 
ATOM   7912  C CE2 . TRP B 2 273 ? 200.839 156.234 127.775 1.00 53.94  ? 291  TRP C CE2 1 
ATOM   7913  C CE3 . TRP B 2 273 ? 201.045 155.673 130.107 1.00 53.94  ? 291  TRP C CE3 1 
ATOM   7914  C CZ2 . TRP B 2 273 ? 201.397 155.006 127.401 1.00 53.94  ? 291  TRP C CZ2 1 
ATOM   7915  C CZ3 . TRP B 2 273 ? 201.631 154.449 129.743 1.00 53.94  ? 291  TRP C CZ3 1 
ATOM   7916  C CH2 . TRP B 2 273 ? 201.820 154.119 128.398 1.00 53.94  ? 291  TRP C CH2 1 
ATOM   7917  N N   . VAL B 2 274 ? 197.175 160.281 129.775 1.00 40.29  ? 292  VAL C N   1 
ATOM   7918  C CA  . VAL B 2 274 ? 196.076 160.803 128.956 1.00 40.29  ? 292  VAL C CA  1 
ATOM   7919  C C   . VAL B 2 274 ? 196.556 161.877 128.010 1.00 40.29  ? 292  VAL C C   1 
ATOM   7920  O O   . VAL B 2 274 ? 197.508 162.580 128.320 1.00 40.29  ? 292  VAL C O   1 
ATOM   7921  C CB  . VAL B 2 274 ? 194.927 161.283 129.854 1.00 56.74  ? 292  VAL C CB  1 
ATOM   7922  C CG1 . VAL B 2 274 ? 193.829 162.067 129.133 1.00 56.74  ? 292  VAL C CG1 1 
ATOM   7923  C CG2 . VAL B 2 274 ? 194.287 160.073 130.526 1.00 56.74  ? 292  VAL C CG2 1 
ATOM   7924  N N   . ALA B 2 275 ? 195.899 162.033 126.866 1.00 40.29  ? 293  ALA C N   1 
ATOM   7925  C CA  . ALA B 2 275 ? 196.281 163.048 125.902 1.00 40.29  ? 293  ALA C CA  1 
ATOM   7926  C C   . ALA B 2 275 ? 195.131 163.895 125.368 1.00 40.29  ? 293  ALA C C   1 
ATOM   7927  O O   . ALA B 2 275 ? 194.005 163.433 125.173 1.00 40.29  ? 293  ALA C O   1 
ATOM   7928  C CB  . ALA B 2 275 ? 197.053 162.404 124.756 1.00 54.43  ? 293  ALA C CB  1 
ATOM   7929  N N   . SER B 2 276 ? 195.504 165.132 125.056 1.00 40.29  ? 294  SER C N   1 
ATOM   7930  C CA  . SER B 2 276 ? 194.812 166.050 124.167 1.00 40.29  ? 294  SER C CA  1 
ATOM   7931  C C   . SER B 2 276 ? 194.478 165.394 122.843 1.00 40.29  ? 294  SER C C   1 
ATOM   7932  O O   . SER B 2 276 ? 195.236 164.547 122.378 1.00 40.29  ? 294  SER C O   1 
ATOM   7933  C CB  . SER B 2 276 ? 195.750 167.212 123.836 1.00 53.66  ? 294  SER C CB  1 
ATOM   7934  O OG  . SER B 2 276 ? 196.880 166.731 123.116 1.00 53.66  ? 294  SER C OG  1 
ATOM   7935  N N   . ASP B 2 277 ? 193.468 165.886 122.147 1.00 40.29  ? 295  ASP C N   1 
ATOM   7936  C CA  . ASP B 2 277 ? 193.066 165.306 120.873 1.00 40.29  ? 295  ASP C CA  1 
ATOM   7937  C C   . ASP B 2 277 ? 194.071 165.571 119.741 1.00 40.29  ? 295  ASP C C   1 
ATOM   7938  O O   . ASP B 2 277 ? 193.989 164.957 118.679 1.00 40.29  ? 295  ASP C O   1 
ATOM   7939  C CB  . ASP B 2 277 ? 191.655 165.736 120.503 1.00 51.30  ? 295  ASP C CB  1 
ATOM   7940  C CG  . ASP B 2 277 ? 191.490 167.207 120.164 1.00 51.30  ? 295  ASP C CG  1 
ATOM   7941  O OD1 . ASP B 2 277 ? 192.508 167.929 120.085 1.00 51.30  ? 295  ASP C OD1 1 
ATOM   7942  O OD2 . ASP B 2 277 ? 190.334 167.656 120.040 1.00 51.30  ? 295  ASP C OD2 1 
ATOM   7943  N N   . GLY B 2 278 ? 195.101 166.383 119.992 1.00 40.29  ? 296  GLY C N   1 
ATOM   7944  C CA  . GLY B 2 278 ? 196.318 166.396 119.185 1.00 40.29  ? 296  GLY C CA  1 
ATOM   7945  C C   . GLY B 2 278 ? 196.987 165.020 119.083 1.00 40.29  ? 296  GLY C C   1 
ATOM   7946  O O   . GLY B 2 278 ? 197.726 164.750 118.145 1.00 40.29  ? 296  GLY C O   1 
ATOM   7947  N N   . TRP B 2 279 ? 196.665 164.134 120.017 1.00 40.29  ? 297  TRP C N   1 
ATOM   7948  C CA  . TRP B 2 279 ? 196.664 162.701 119.815 1.00 40.29  ? 297  TRP C CA  1 
ATOM   7949  C C   . TRP B 2 279 ? 195.371 162.115 120.392 1.00 40.29  ? 297  TRP C C   1 
ATOM   7950  O O   . TRP B 2 279 ? 195.341 161.538 121.468 1.00 40.29  ? 297  TRP C O   1 
ATOM   7951  C CB  . TRP B 2 279 ? 197.925 162.033 120.354 1.00 53.94  ? 297  TRP C CB  1 
ATOM   7952  C CG  . TRP B 2 279 ? 197.803 160.551 120.238 1.00 53.94  ? 297  TRP C CG  1 
ATOM   7953  C CD1 . TRP B 2 279 ? 197.569 159.899 119.084 1.00 53.94  ? 297  TRP C CD1 1 
ATOM   7954  C CD2 . TRP B 2 279 ? 197.623 159.562 121.289 1.00 53.94  ? 297  TRP C CD2 1 
ATOM   7955  N NE1 . TRP B 2 279 ? 197.159 158.613 119.356 1.00 53.94  ? 297  TRP C NE1 1 
ATOM   7956  C CE2 . TRP B 2 279 ? 197.139 158.362 120.700 1.00 53.94  ? 297  TRP C CE2 1 
ATOM   7957  C CE3 . TRP B 2 279 ? 197.772 159.571 122.687 1.00 53.94  ? 297  TRP C CE3 1 
ATOM   7958  C CZ2 . TRP B 2 279 ? 196.756 157.254 121.457 1.00 53.94  ? 297  TRP C CZ2 1 
ATOM   7959  C CZ3 . TRP B 2 279 ? 197.436 158.443 123.459 1.00 53.94  ? 297  TRP C CZ3 1 
ATOM   7960  C CH2 . TRP B 2 279 ? 196.918 157.292 122.846 1.00 53.94  ? 297  TRP C CH2 1 
ATOM   7961  N N   . GLY B 2 280 ? 194.271 162.318 119.671 1.00 40.29  ? 298  GLY C N   1 
ATOM   7962  C CA  . GLY B 2 280 ? 192.981 161.685 119.930 1.00 40.29  ? 298  GLY C CA  1 
ATOM   7963  C C   . GLY B 2 280 ? 192.760 160.509 118.987 1.00 40.29  ? 298  GLY C C   1 
ATOM   7964  O O   . GLY B 2 280 ? 192.951 160.660 117.784 1.00 40.29  ? 298  GLY C O   1 
ATOM   7965  N N   . ALA B 2 281 ? 192.355 159.347 119.499 1.00 19.07  ? 299  ALA C N   1 
ATOM   7966  C CA  . ALA B 2 281 ? 192.280 158.116 118.710 1.00 19.07  ? 299  ALA C CA  1 
ATOM   7967  C C   . ALA B 2 281 ? 193.620 157.860 118.024 1.00 19.07  ? 299  ALA C C   1 
ATOM   7968  O O   . ALA B 2 281 ? 194.583 157.558 118.722 1.00 19.07  ? 299  ALA C O   1 
ATOM   7969  C CB  . ALA B 2 281 ? 191.051 158.117 117.787 1.00 25.76  ? 299  ALA C CB  1 
ATOM   7970  N N   . LEU B 2 282 ? 193.729 158.029 116.707 1.00 40.29  ? 300  LEU C N   1 
ATOM   7971  C CA  . LEU B 2 282 ? 195.016 157.961 116.019 1.00 40.29  ? 300  LEU C CA  1 
ATOM   7972  C C   . LEU B 2 282 ? 195.706 156.635 116.317 1.00 40.29  ? 300  LEU C C   1 
ATOM   7973  O O   . LEU B 2 282 ? 196.754 156.521 116.949 1.00 40.29  ? 300  LEU C O   1 
ATOM   7974  C CB  . LEU B 2 282 ? 195.835 159.211 116.345 1.00 57.27  ? 300  LEU C CB  1 
ATOM   7975  C CG  . LEU B 2 282 ? 195.399 160.402 115.494 1.00 57.27  ? 300  LEU C CG  1 
ATOM   7976  C CD1 . LEU B 2 282 ? 195.763 161.702 116.199 1.00 57.27  ? 300  LEU C CD1 1 
ATOM   7977  C CD2 . LEU B 2 282 ? 196.107 160.366 114.143 1.00 57.27  ? 300  LEU C CD2 1 
ATOM   7978  N N   . GLU B 2 283 ? 195.047 155.626 115.789 1.00 40.29  ? 301  GLU C N   1 
ATOM   7979  C CA  . GLU B 2 283 ? 195.451 154.236 115.678 1.00 40.29  ? 301  GLU C CA  1 
ATOM   7980  C C   . GLU B 2 283 ? 196.886 154.132 115.138 1.00 40.29  ? 301  GLU C C   1 
ATOM   7981  O O   . GLU B 2 283 ? 197.669 153.263 115.506 1.00 40.29  ? 301  GLU C O   1 
ATOM   7982  C CB  . GLU B 2 283 ? 194.490 153.562 114.682 1.00 53.75  ? 301  GLU C CB  1 
ATOM   7983  C CG  . GLU B 2 283 ? 192.981 153.613 115.016 1.00 53.75  ? 301  GLU C CG  1 
ATOM   7984  C CD  . GLU B 2 283 ? 192.289 154.994 114.905 1.00 53.75  ? 301  GLU C CD  1 
ATOM   7985  O OE1 . GLU B 2 283 ? 192.823 155.907 114.235 1.00 53.75  ? 301  GLU C OE1 1 
ATOM   7986  O OE2 . GLU B 2 283 ? 191.204 155.169 115.496 1.00 53.75  ? 301  GLU C OE2 1 
ATOM   7987  N N   . SER B 2 284 ? 197.239 155.087 114.280 1.00 40.29  ? 302  SER C N   1 
ATOM   7988  C CA  . SER B 2 284 ? 198.551 155.255 113.678 1.00 40.29  ? 302  SER C CA  1 
ATOM   7989  C C   . SER B 2 284 ? 199.657 155.430 114.709 1.00 40.29  ? 302  SER C C   1 
ATOM   7990  O O   . SER B 2 284 ? 200.759 154.929 114.514 1.00 40.29  ? 302  SER C O   1 
ATOM   7991  C CB  . SER B 2 284 ? 198.488 156.491 112.782 1.00 53.66  ? 302  SER C CB  1 
ATOM   7992  O OG  . SER B 2 284 ? 198.185 157.638 113.559 1.00 53.66  ? 302  SER C OG  1 
ATOM   7993  N N   . VAL B 2 285 ? 199.409 156.141 115.804 1.00 40.29  ? 303  VAL C N   1 
ATOM   7994  C CA  . VAL B 2 285 ? 200.394 156.331 116.872 1.00 40.29  ? 303  VAL C CA  1 
ATOM   7995  C C   . VAL B 2 285 ? 200.586 155.033 117.650 1.00 40.29  ? 303  VAL C C   1 
ATOM   7996  O O   . VAL B 2 285 ? 201.719 154.642 117.912 1.00 40.29  ? 303  VAL C O   1 
ATOM   7997  C CB  . VAL B 2 285 ? 199.952 157.497 117.767 1.00 56.74  ? 303  VAL C CB  1 
ATOM   7998  C CG1 . VAL B 2 285 ? 200.600 157.538 119.151 1.00 56.74  ? 303  VAL C CG1 1 
ATOM   7999  C CG2 . VAL B 2 285 ? 200.264 158.811 117.048 1.00 56.74  ? 303  VAL C CG2 1 
ATOM   8000  N N   . VAL B 2 286 ? 199.497 154.333 117.967 1.00 40.29  ? 304  VAL C N   1 
ATOM   8001  C CA  . VAL B 2 286 ? 199.496 153.124 118.816 1.00 40.29  ? 304  VAL C CA  1 
ATOM   8002  C C   . VAL B 2 286 ? 199.954 151.837 118.114 1.00 40.29  ? 304  VAL C C   1 
ATOM   8003  O O   . VAL B 2 286 ? 199.927 150.771 118.718 1.00 40.29  ? 304  VAL C O   1 
ATOM   8004  C CB  . VAL B 2 286 ? 198.136 152.939 119.514 1.00 56.74  ? 304  VAL C CB  1 
ATOM   8005  C CG1 . VAL B 2 286 ? 197.828 154.147 120.401 1.00 56.74  ? 304  VAL C CG1 1 
ATOM   8006  C CG2 . VAL B 2 286 ? 196.998 152.808 118.518 1.00 56.74  ? 304  VAL C CG2 1 
ATOM   8007  N N   . ALA B 2 287 ? 200.417 151.905 116.864 1.00 40.29  ? 305  ALA C N   1 
ATOM   8008  C CA  . ALA B 2 287 ? 200.824 150.733 116.083 1.00 40.29  ? 305  ALA C CA  1 
ATOM   8009  C C   . ALA B 2 287 ? 202.199 150.136 116.476 1.00 40.29  ? 305  ALA C C   1 
ATOM   8010  O O   . ALA B 2 287 ? 202.329 148.928 116.661 1.00 40.29  ? 305  ALA C O   1 
ATOM   8011  C CB  . ALA B 2 287 ? 200.797 151.141 114.608 1.00 54.43  ? 305  ALA C CB  1 
ATOM   8012  N N   . GLY B 2 288 ? 203.220 150.978 116.663 1.00 40.87  ? 306  GLY C N   1 
ATOM   8013  C CA  . GLY B 2 288 ? 204.553 150.591 117.155 1.00 40.87  ? 306  GLY C CA  1 
ATOM   8014  C C   . GLY B 2 288 ? 204.603 150.146 118.621 1.00 40.87  ? 306  GLY C C   1 
ATOM   8015  O O   . GLY B 2 288 ? 205.627 149.633 119.075 1.00 40.87  ? 306  GLY C O   1 
ATOM   8016  N N   . SER B 2 289 ? 203.517 150.344 119.365 1.00 40.29  ? 307  SER C N   1 
ATOM   8017  C CA  . SER B 2 289 ? 203.495 150.299 120.830 1.00 40.29  ? 307  SER C CA  1 
ATOM   8018  C C   . SER B 2 289 ? 202.093 149.992 121.369 1.00 40.29  ? 307  SER C C   1 
ATOM   8019  O O   . SER B 2 289 ? 201.658 150.572 122.366 1.00 40.29  ? 307  SER C O   1 
ATOM   8020  C CB  . SER B 2 289 ? 203.952 151.647 121.390 1.00 53.66  ? 307  SER C CB  1 
ATOM   8021  O OG  . SER B 2 289 ? 205.263 152.012 121.016 1.00 53.66  ? 307  SER C OG  1 
ATOM   8022  N N   . GLU B 2 290 ? 201.352 149.106 120.698 1.00 40.29  ? 308  GLU C N   1 
ATOM   8023  C CA  . GLU B 2 290 ? 200.010 148.721 121.088 1.00 40.29  ? 308  GLU C CA  1 
ATOM   8024  C C   . GLU B 2 290 ? 199.911 148.369 122.572 1.00 40.29  ? 308  GLU C C   1 
ATOM   8025  O O   . GLU B 2 290 ? 198.916 148.691 123.219 1.00 40.29  ? 308  GLU C O   1 
ATOM   8026  C CB  . GLU B 2 290 ? 199.588 147.521 120.225 1.00 53.01  ? 308  GLU C CB  1 
ATOM   8027  C CG  . GLU B 2 290 ? 198.200 147.105 120.377 1.00 53.01  ? 308  GLU C CG  1 
ATOM   8028  C CD  . GLU B 2 290 ? 197.771 145.954 119.481 1.00 53.01  ? 308  GLU C CD  1 
ATOM   8029  O OE1 . GLU B 2 290 ? 198.374 144.909 119.582 1.00 53.01  ? 308  GLU C OE1 1 
ATOM   8030  O OE2 . GLU B 2 290 ? 196.859 146.122 118.670 1.00 53.01  ? 308  GLU C OE2 1 
ATOM   8031  N N   . GLY B 2 291 ? 200.913 147.669 123.105 1.00 43.23  ? 309  GLY C N   1 
ATOM   8032  C CA  . GLY B 2 291 ? 200.918 147.274 124.510 1.00 43.23  ? 309  GLY C CA  1 
ATOM   8033  C C   . GLY B 2 291 ? 200.979 148.468 125.470 1.00 43.23  ? 309  GLY C C   1 
ATOM   8034  O O   . GLY B 2 291 ? 200.118 148.645 126.328 1.00 43.23  ? 309  GLY C O   1 
ATOM   8035  N N   . ALA B 2 292 ? 201.980 149.336 125.328 1.00 40.29  ? 310  ALA C N   1 
ATOM   8036  C CA  . ALA B 2 292 ? 202.102 150.527 126.165 1.00 40.29  ? 310  ALA C CA  1 
ATOM   8037  C C   . ALA B 2 292 ? 200.865 151.424 126.019 1.00 40.29  ? 310  ALA C C   1 
ATOM   8038  O O   . ALA B 2 292 ? 200.374 151.964 127.006 1.00 40.29  ? 310  ALA C O   1 
ATOM   8039  C CB  . ALA B 2 292 ? 203.386 151.281 125.802 1.00 54.43  ? 310  ALA C CB  1 
ATOM   8040  N N   . ALA B 2 293 ? 200.301 151.506 124.811 1.00 40.29  ? 311  ALA C N   1 
ATOM   8041  C CA  . ALA B 2 293 ? 199.116 152.302 124.521 1.00 40.29  ? 311  ALA C CA  1 
ATOM   8042  C C   . ALA B 2 293 ? 197.886 151.940 125.365 1.00 40.29  ? 311  ALA C C   1 
ATOM   8043  O O   . ALA B 2 293 ? 196.945 152.726 125.407 1.00 40.29  ? 311  ALA C O   1 
ATOM   8044  C CB  . ALA B 2 293 ? 198.788 152.146 123.038 1.00 54.43  ? 311  ALA C CB  1 
ATOM   8045  N N   . GLU B 2 294 ? 197.857 150.784 126.034 1.00 40.29  ? 312  GLU C N   1 
ATOM   8046  C CA  . GLU B 2 294 ? 196.680 150.405 126.787 1.00 40.29  ? 312  GLU C CA  1 
ATOM   8047  C C   . GLU B 2 294 ? 196.394 151.335 127.945 1.00 40.29  ? 312  GLU C C   1 
ATOM   8048  O O   . GLU B 2 294 ? 195.239 151.613 128.240 1.00 40.29  ? 312  GLU C O   1 
ATOM   8049  C CB  . GLU B 2 294 ? 196.859 149.041 127.449 1.00 53.10  ? 312  GLU C CB  1 
ATOM   8050  C CG  . GLU B 2 294 ? 196.891 147.888 126.572 1.00 53.10  ? 312  GLU C CG  1 
ATOM   8051  C CD  . GLU B 2 294 ? 197.190 146.588 127.355 1.00 53.10  ? 312  GLU C CD  1 
ATOM   8052  O OE1 . GLU B 2 294 ? 197.375 146.680 128.541 1.00 53.10  ? 312  GLU C OE1 1 
ATOM   8053  O OE2 . GLU B 2 294 ? 197.248 145.515 126.779 1.00 53.10  ? 312  GLU C OE2 1 
ATOM   8054  N N   . GLY B 2 295 ? 197.438 151.798 128.632 1.00 40.29  ? 313  GLY C N   1 
ATOM   8055  C CA  . GLY B 2 295 ? 197.332 152.532 129.891 1.00 40.29  ? 313  GLY C CA  1 
ATOM   8056  C C   . GLY B 2 295 ? 196.827 153.962 129.722 1.00 40.29  ? 313  GLY C C   1 
ATOM   8057  O O   . GLY B 2 295 ? 197.319 154.852 130.411 1.00 40.29  ? 313  GLY C O   1 
ATOM   8058  N N   . ALA B 2 296 ? 195.927 154.222 128.771 1.00 40.29  ? 314  ALA C N   1 
ATOM   8059  C CA  . ALA B 2 296 ? 195.624 155.577 128.377 1.00 40.29  ? 314  ALA C CA  1 
ATOM   8060  C C   . ALA B 2 296 ? 194.218 155.845 127.852 1.00 40.29  ? 314  ALA C C   1 
ATOM   8061  O O   . ALA B 2 296 ? 193.527 154.995 127.280 1.00 40.29  ? 314  ALA C O   1 
ATOM   8062  C CB  . ALA B 2 296 ? 196.692 156.029 127.372 1.00 54.43  ? 314  ALA C CB  1 
ATOM   8063  N N   . ILE B 2 297 ? 193.840 157.111 128.007 1.00 40.29  ? 315  ILE C N   1 
ATOM   8064  C CA  . ILE B 2 297 ? 192.643 157.727 127.448 1.00 40.29  ? 315  ILE C CA  1 
ATOM   8065  C C   . ILE B 2 297 ? 193.032 158.922 126.595 1.00 40.29  ? 315  ILE C C   1 
ATOM   8066  O O   . ILE B 2 297 ? 193.999 159.623 126.867 1.00 40.29  ? 315  ILE C O   1 
ATOM   8067  C CB  . ILE B 2 297 ? 191.651 158.100 128.563 1.00 57.27  ? 315  ILE C CB  1 
ATOM   8068  C CG1 . ILE B 2 297 ? 190.878 156.835 128.947 1.00 57.27  ? 315  ILE C CG1 1 
ATOM   8069  C CG2 . ILE B 2 297 ? 190.669 159.236 128.215 1.00 57.27  ? 315  ILE C CG2 1 
ATOM   8070  C CD1 . ILE B 2 297 ? 190.253 156.895 130.339 1.00 57.27  ? 315  ILE C CD1 1 
ATOM   8071  N N   . THR B 2 298 ? 192.233 159.186 125.577 1.00 40.29  ? 316  THR C N   1 
ATOM   8072  C CA  . THR B 2 298 ? 192.328 160.422 124.823 1.00 40.29  ? 316  THR C CA  1 
ATOM   8073  C C   . THR B 2 298 ? 190.970 161.073 124.746 1.00 40.29  ? 316  THR C C   1 
ATOM   8074  O O   . THR B 2 298 ? 189.936 160.408 124.683 1.00 40.29  ? 316  THR C O   1 
ATOM   8075  C CB  . THR B 2 298 ? 192.905 160.223 123.421 1.00 55.15  ? 316  THR C CB  1 
ATOM   8076  O OG1 . THR B 2 298 ? 192.013 159.514 122.591 1.00 55.15  ? 316  THR C OG1 1 
ATOM   8077  C CG2 . THR B 2 298 ? 194.211 159.438 123.432 1.00 55.15  ? 316  THR C CG2 1 
ATOM   8078  N N   . ILE B 2 299 ? 190.995 162.393 124.704 1.00 40.29  ? 317  ILE C N   1 
ATOM   8079  C CA  . ILE B 2 299 ? 189.894 163.149 124.139 1.00 40.29  ? 317  ILE C CA  1 
ATOM   8080  C C   . ILE B 2 299 ? 189.970 163.129 122.613 1.00 40.29  ? 317  ILE C C   1 
ATOM   8081  O O   . ILE B 2 299 ? 191.044 163.084 122.024 1.00 40.29  ? 317  ILE C O   1 
ATOM   8082  C CB  . ILE B 2 299 ? 189.875 164.576 124.708 1.00 57.27  ? 317  ILE C CB  1 
ATOM   8083  C CG1 . ILE B 2 299 ? 188.810 165.453 124.019 1.00 57.27  ? 317  ILE C CG1 1 
ATOM   8084  C CG2 . ILE B 2 299 ? 191.262 165.229 124.612 1.00 57.27  ? 317  ILE C CG2 1 
ATOM   8085  C CD1 . ILE B 2 299 ? 188.411 166.676 124.851 1.00 57.27  ? 317  ILE C CD1 1 
ATOM   8086  N N   . GLU B 2 300 ? 188.823 163.226 121.967 1.00 40.29  ? 318  GLU C N   1 
ATOM   8087  C CA  . GLU B 2 300 ? 188.690 163.818 120.648 1.00 40.29  ? 318  GLU C CA  1 
ATOM   8088  C C   . GLU B 2 300 ? 187.529 164.786 120.717 1.00 40.29  ? 318  GLU C C   1 
ATOM   8089  O O   . GLU B 2 300 ? 186.586 164.544 121.458 1.00 40.29  ? 318  GLU C O   1 
ATOM   8090  C CB  . GLU B 2 300 ? 188.481 162.757 119.565 1.00 53.10  ? 318  GLU C CB  1 
ATOM   8091  C CG  . GLU B 2 300 ? 188.406 163.312 118.146 1.00 53.10  ? 318  GLU C CG  1 
ATOM   8092  C CD  . GLU B 2 300 ? 189.700 163.959 117.651 1.00 53.10  ? 318  GLU C CD  1 
ATOM   8093  O OE1 . GLU B 2 300 ? 190.743 163.770 118.305 1.00 53.10  ? 318  GLU C OE1 1 
ATOM   8094  O OE2 . GLU B 2 300 ? 189.679 164.586 116.568 1.00 53.10  ? 318  GLU C OE2 1 
ATOM   8095  N N   . LEU B 2 301 ? 187.505 165.845 119.933 1.00 40.29  ? 319  LEU C N   1 
ATOM   8096  C CA  . LEU B 2 301 ? 186.227 166.445 119.617 1.00 40.29  ? 319  LEU C CA  1 
ATOM   8097  C C   . LEU B 2 301 ? 185.359 165.399 118.916 1.00 40.29  ? 319  LEU C C   1 
ATOM   8098  O O   . LEU B 2 301 ? 185.779 164.732 117.976 1.00 40.29  ? 319  LEU C O   1 
ATOM   8099  C CB  . LEU B 2 301 ? 186.461 167.720 118.817 1.00 57.27  ? 319  LEU C CB  1 
ATOM   8100  C CG  . LEU B 2 301 ? 185.285 168.701 118.894 1.00 57.27  ? 319  LEU C CG  1 
ATOM   8101  C CD1 . LEU B 2 301 ? 185.766 170.073 118.427 1.00 57.27  ? 319  LEU C CD1 1 
ATOM   8102  C CD2 . LEU B 2 301 ? 184.078 168.269 118.063 1.00 57.27  ? 319  LEU C CD2 1 
ATOM   8103  N N   . ALA B 2 302 ? 184.166 165.186 119.447 1.00 40.29  ? 320  ALA C N   1 
ATOM   8104  C CA  . ALA B 2 302 ? 183.254 164.158 119.052 1.00 40.29  ? 320  ALA C CA  1 
ATOM   8105  C C   . ALA B 2 302 ? 182.863 164.370 117.616 1.00 40.29  ? 320  ALA C C   1 
ATOM   8106  O O   . ALA B 2 302 ? 182.616 165.492 117.194 1.00 40.29  ? 320  ALA C O   1 
ATOM   8107  C CB  . ALA B 2 302 ? 182.070 164.155 119.982 1.00 54.43  ? 320  ALA C CB  1 
ATOM   8108  N N   . SER B 2 303 ? 182.799 163.283 116.873 1.00 40.29  ? 321  SER C N   1 
ATOM   8109  C CA  . SER B 2 303 ? 182.466 163.323 115.466 1.00 40.29  ? 321  SER C CA  1 
ATOM   8110  C C   . SER B 2 303 ? 181.020 163.067 115.144 1.00 40.29  ? 321  SER C C   1 
ATOM   8111  O O   . SER B 2 303 ? 180.467 162.023 115.497 1.00 40.29  ? 321  SER C O   1 
ATOM   8112  C CB  . SER B 2 303 ? 183.298 162.306 114.735 1.00 53.66  ? 321  SER C CB  1 
ATOM   8113  O OG  . SER B 2 303 ? 182.875 162.178 113.419 1.00 53.66  ? 321  SER C OG  1 
ATOM   8114  N N   . TYR B 2 304 ? 180.417 164.010 114.440 1.00 40.29  ? 322  TYR C N   1 
ATOM   8115  C CA  . TYR B 2 304 ? 179.036 163.912 114.020 1.00 40.29  ? 322  TYR C CA  1 
ATOM   8116  C C   . TYR B 2 304 ? 178.944 164.216 112.539 1.00 40.29  ? 322  TYR C C   1 
ATOM   8117  O O   . TYR B 2 304 ? 178.417 165.267 112.178 1.00 40.29  ? 322  TYR C O   1 
ATOM   8118  C CB  . TYR B 2 304 ? 178.218 164.921 114.783 1.00 54.08  ? 322  TYR C CB  1 
ATOM   8119  C CG  . TYR B 2 304 ? 178.422 164.793 116.210 1.00 54.08  ? 322  TYR C CG  1 
ATOM   8120  C CD1 . TYR B 2 304 ? 177.798 163.807 116.908 1.00 54.08  ? 322  TYR C CD1 1 
ATOM   8121  C CD2 . TYR B 2 304 ? 179.274 165.669 116.845 1.00 54.08  ? 322  TYR C CD2 1 
ATOM   8122  C CE1 . TYR B 2 304 ? 178.009 163.697 118.256 1.00 54.08  ? 322  TYR C CE1 1 
ATOM   8123  C CE2 . TYR B 2 304 ? 179.478 165.575 118.171 1.00 54.08  ? 322  TYR C CE2 1 
ATOM   8124  C CZ  . TYR B 2 304 ? 178.833 164.578 118.892 1.00 54.08  ? 322  TYR C CZ  1 
ATOM   8125  O OH  . TYR B 2 304 ? 179.014 164.479 120.252 1.00 54.08  ? 322  TYR C OH  1 
ATOM   8126  N N   . PRO B 2 305 ? 179.429 163.338 111.649 1.00 40.29  ? 323  PRO C N   1 
ATOM   8127  C CA  . PRO B 2 305 ? 179.563 163.594 110.237 1.00 40.29  ? 323  PRO C CA  1 
ATOM   8128  C C   . PRO B 2 305 ? 178.191 163.826 109.667 1.00 40.29  ? 323  PRO C C   1 
ATOM   8129  O O   . PRO B 2 305 ? 177.236 163.184 110.100 1.00 40.29  ? 323  PRO C O   1 
ATOM   8130  C CB  . PRO B 2 305 ? 180.138 162.280 109.695 1.00 68.85  ? 323  PRO C CB  1 
ATOM   8131  C CG  . PRO B 2 305 ? 180.722 161.594 110.896 1.00 68.85  ? 323  PRO C CG  1 
ATOM   8132  C CD  . PRO B 2 305 ? 179.792 161.966 112.024 1.00 68.85  ? 323  PRO C CD  1 
ATOM   8133  N N   . ILE B 2 306 ? 178.116 164.662 108.652 1.00 40.29  ? 324  ILE C N   1 
ATOM   8134  C CA  . ILE B 2 306 ? 176.854 164.900 107.990 1.00 40.29  ? 324  ILE C CA  1 
ATOM   8135  C C   . ILE B 2 306 ? 176.703 163.932 106.844 1.00 40.29  ? 324  ILE C C   1 
ATOM   8136  O O   . ILE B 2 306 ? 177.261 164.154 105.762 1.00 40.29  ? 324  ILE C O   1 
ATOM   8137  C CB  . ILE B 2 306 ? 176.811 166.348 107.471 1.00 57.27  ? 324  ILE C CB  1 
ATOM   8138  C CG1 . ILE B 2 306 ? 176.943 167.297 108.658 1.00 57.27  ? 324  ILE C CG1 1 
ATOM   8139  C CG2 . ILE B 2 306 ? 175.552 166.592 106.705 1.00 57.27  ? 324  ILE C CG2 1 
ATOM   8140  C CD1 . ILE B 2 306 ? 177.145 168.734 108.282 1.00 57.27  ? 324  ILE C CD1 1 
ATOM   8141  N N   . SER B 2 307 ? 175.862 162.917 107.045 1.00 40.29  ? 325  SER C N   1 
ATOM   8142  C CA  . SER B 2 307 ? 175.680 161.861 106.066 1.00 40.29  ? 325  SER C CA  1 
ATOM   8143  C C   . SER B 2 307 ? 174.986 162.383 104.830 1.00 40.29  ? 325  SER C C   1 
ATOM   8144  O O   . SER B 2 307 ? 175.235 161.901 103.722 1.00 40.29  ? 325  SER C O   1 
ATOM   8145  C CB  . SER B 2 307 ? 174.868 160.749 106.676 1.00 53.66  ? 325  SER C CB  1 
ATOM   8146  O OG  . SER B 2 307 ? 173.572 161.189 106.947 1.00 53.66  ? 325  SER C OG  1 
ATOM   8147  N N   . ASP B 2 308 ? 174.203 163.446 104.995 1.00 40.29  ? 326  ASP C N   1 
ATOM   8148  C CA  . ASP B 2 308 ? 173.508 164.038 103.869 1.00 40.29  ? 326  ASP C CA  1 
ATOM   8149  C C   . ASP B 2 308 ? 174.489 164.618 102.881 1.00 40.29  ? 326  ASP C C   1 
ATOM   8150  O O   . ASP B 2 308 ? 174.239 164.627 101.679 1.00 40.29  ? 326  ASP C O   1 
ATOM   8151  C CB  . ASP B 2 308 ? 172.606 165.194 104.311 1.00 51.30  ? 326  ASP C CB  1 
ATOM   8152  C CG  . ASP B 2 308 ? 171.398 164.786 105.125 1.00 51.30  ? 326  ASP C CG  1 
ATOM   8153  O OD1 . ASP B 2 308 ? 171.100 163.626 105.221 1.00 51.30  ? 326  ASP C OD1 1 
ATOM   8154  O OD2 . ASP B 2 308 ? 170.742 165.665 105.610 1.00 51.30  ? 326  ASP C OD2 1 
ATOM   8155  N N   . PHE B 2 309 ? 175.596 165.155 103.379 1.00 40.29  ? 327  PHE C N   1 
ATOM   8156  C CA  . PHE B 2 309 ? 176.539 165.797 102.512 1.00 40.29  ? 327  PHE C CA  1 
ATOM   8157  C C   . PHE B 2 309 ? 177.453 164.758 101.966 1.00 40.29  ? 327  PHE C C   1 
ATOM   8158  O O   . PHE B 2 309 ? 177.927 164.878 100.841 1.00 40.29  ? 327  PHE C O   1 
ATOM   8159  C CB  . PHE B 2 309 ? 177.276 166.909 103.218 1.00 54.49  ? 327  PHE C CB  1 
ATOM   8160  C CG  . PHE B 2 309 ? 176.434 168.168 103.461 1.00 54.49  ? 327  PHE C CG  1 
ATOM   8161  C CD1 . PHE B 2 309 ? 175.024 168.210 103.363 1.00 54.49  ? 327  PHE C CD1 1 
ATOM   8162  C CD2 . PHE B 2 309 ? 177.068 169.337 103.751 1.00 54.49  ? 327  PHE C CD2 1 
ATOM   8163  C CE1 . PHE B 2 309 ? 174.343 169.371 103.568 1.00 54.49  ? 327  PHE C CE1 1 
ATOM   8164  C CE2 . PHE B 2 309 ? 176.374 170.480 103.934 1.00 54.49  ? 327  PHE C CE2 1 
ATOM   8165  C CZ  . PHE B 2 309 ? 175.016 170.504 103.850 1.00 54.49  ? 327  PHE C CZ  1 
ATOM   8166  N N   . ALA B 2 310 ? 177.697 163.704 102.743 1.00 40.29  ? 328  ALA C N   1 
ATOM   8167  C CA  . ALA B 2 310 ? 178.526 162.646 102.221 1.00 40.29  ? 328  ALA C CA  1 
ATOM   8168  C C   . ALA B 2 310 ? 177.847 162.065 101.009 1.00 40.29  ? 328  ALA C C   1 
ATOM   8169  O O   . ALA B 2 310 ? 178.495 161.727 100.020 1.00 40.29  ? 328  ALA C O   1 
ATOM   8170  C CB  . ALA B 2 310 ? 178.740 161.550 103.239 1.00 54.43  ? 328  ALA C CB  1 
ATOM   8171  N N   . SER B 2 311 ? 176.520 161.966 101.088 1.00 40.29  ? 329  SER C N   1 
ATOM   8172  C CA  . SER B 2 311 ? 175.714 161.460 100.007 1.00 40.29  ? 329  SER C CA  1 
ATOM   8173  C C   . SER B 2 311 ? 175.782 162.400 98.826  1.00 40.29  ? 329  SER C C   1 
ATOM   8174  O O   . SER B 2 311 ? 176.029 161.966 97.694  1.00 40.29  ? 329  SER C O   1 
ATOM   8175  C CB  . SER B 2 311 ? 174.284 161.314 100.464 1.00 53.66  ? 329  SER C CB  1 
ATOM   8176  O OG  . SER B 2 311 ? 173.470 160.835 99.435  1.00 53.66  ? 329  SER C OG  1 
ATOM   8177  N N   . TYR B 2 312 ? 175.631 163.702 99.085  1.00 40.29  ? 330  TYR C N   1 
ATOM   8178  C CA  . TYR B 2 312 ? 175.660 164.658 98.003  1.00 40.29  ? 330  TYR C CA  1 
ATOM   8179  C C   . TYR B 2 312 ? 177.011 164.646 97.313  1.00 40.29  ? 330  TYR C C   1 
ATOM   8180  O O   . TYR B 2 312 ? 177.082 164.703 96.087  1.00 40.29  ? 330  TYR C O   1 
ATOM   8181  C CB  . TYR B 2 312 ? 175.444 166.074 98.526  1.00 54.08  ? 330  TYR C CB  1 
ATOM   8182  C CG  . TYR B 2 312 ? 174.128 166.399 99.165  1.00 54.08  ? 330  TYR C CG  1 
ATOM   8183  C CD1 . TYR B 2 312 ? 172.997 165.614 98.992  1.00 54.08  ? 330  TYR C CD1 1 
ATOM   8184  C CD2 . TYR B 2 312 ? 174.058 167.543 99.942  1.00 54.08  ? 330  TYR C CD2 1 
ATOM   8185  C CE1 . TYR B 2 312 ? 171.819 165.982 99.606  1.00 54.08  ? 330  TYR C CE1 1 
ATOM   8186  C CE2 . TYR B 2 312 ? 172.888 167.909 100.541 1.00 54.08  ? 330  TYR C CE2 1 
ATOM   8187  C CZ  . TYR B 2 312 ? 171.771 167.135 100.382 1.00 54.08  ? 330  TYR C CZ  1 
ATOM   8188  O OH  . TYR B 2 312 ? 170.589 167.508 100.975 1.00 54.08  ? 330  TYR C OH  1 
ATOM   8189  N N   . PHE B 2 313 ? 178.095 164.560 98.088  1.00 40.29  ? 331  PHE C N   1 
ATOM   8190  C CA  . PHE B 2 313 ? 179.413 164.583 97.496  1.00 40.29  ? 331  PHE C CA  1 
ATOM   8191  C C   . PHE B 2 313 ? 179.647 163.270 96.746  1.00 40.29  ? 331  PHE C C   1 
ATOM   8192  O O   . PHE B 2 313 ? 180.127 163.273 95.620  1.00 40.29  ? 331  PHE C O   1 
ATOM   8193  C CB  . PHE B 2 313 ? 180.524 164.780 98.500  1.00 54.49  ? 331  PHE C CB  1 
ATOM   8194  C CG  . PHE B 2 313 ? 181.807 165.300 97.831  1.00 54.49  ? 331  PHE C CG  1 
ATOM   8195  C CD1 . PHE B 2 313 ? 182.623 164.515 97.024  1.00 54.49  ? 331  PHE C CD1 1 
ATOM   8196  C CD2 . PHE B 2 313 ? 182.144 166.640 97.969  1.00 54.49  ? 331  PHE C CD2 1 
ATOM   8197  C CE1 . PHE B 2 313 ? 183.741 165.042 96.419  1.00 54.49  ? 331  PHE C CE1 1 
ATOM   8198  C CE2 . PHE B 2 313 ? 183.272 167.159 97.362  1.00 54.49  ? 331  PHE C CE2 1 
ATOM   8199  C CZ  . PHE B 2 313 ? 184.064 166.361 96.595  1.00 54.49  ? 331  PHE C CZ  1 
ATOM   8200  N N   . GLN B 2 314 ? 179.269 162.124 97.326  1.00 40.29  ? 332  GLN C N   1 
ATOM   8201  C CA  . GLN B 2 314 ? 179.532 160.845 96.667  1.00 40.29  ? 332  GLN C CA  1 
ATOM   8202  C C   . GLN B 2 314 ? 178.887 160.772 95.296  1.00 40.29  ? 332  GLN C C   1 
ATOM   8203  O O   . GLN B 2 314 ? 179.480 160.237 94.368  1.00 40.29  ? 332  GLN C O   1 
ATOM   8204  C CB  . GLN B 2 314 ? 179.001 159.659 97.497  1.00 54.76  ? 332  GLN C CB  1 
ATOM   8205  C CG  . GLN B 2 314 ? 179.281 158.240 96.877  1.00 54.76  ? 332  GLN C CG  1 
ATOM   8206  C CD  . GLN B 2 314 ? 180.750 157.836 96.851  1.00 54.76  ? 332  GLN C CD  1 
ATOM   8207  O OE1 . GLN B 2 314 ? 181.280 157.357 97.874  1.00 54.76  ? 332  GLN C OE1 1 
ATOM   8208  N NE2 . GLN B 2 314 ? 181.395 158.060 95.711  1.00 54.76  ? 332  GLN C NE2 1 
ATOM   8209  N N   . SER B 2 315 ? 177.692 161.334 95.157  1.00 40.29  ? 333  SER C N   1 
ATOM   8210  C CA  . SER B 2 315 ? 176.957 161.337 93.896  1.00 40.29  ? 333  SER C CA  1 
ATOM   8211  C C   . SER B 2 315 ? 177.260 162.560 93.022  1.00 40.29  ? 333  SER C C   1 
ATOM   8212  O O   . SER B 2 315 ? 176.665 162.734 91.946  1.00 40.29  ? 333  SER C O   1 
ATOM   8213  C CB  . SER B 2 315 ? 175.462 161.277 94.159  1.00 53.66  ? 333  SER C CB  1 
ATOM   8214  O OG  . SER B 2 315 ? 175.082 160.054 94.742  1.00 53.66  ? 333  SER C OG  1 
ATOM   8215  N N   . LEU B 2 316 ? 178.139 163.433 93.501  1.00 40.29  ? 334  LEU C N   1 
ATOM   8216  C CA  . LEU B 2 316 ? 178.488 164.671 92.842  1.00 40.29  ? 334  LEU C CA  1 
ATOM   8217  C C   . LEU B 2 316 ? 179.215 164.371 91.563  1.00 40.29  ? 334  LEU C C   1 
ATOM   8218  O O   . LEU B 2 316 ? 180.108 163.533 91.523  1.00 40.29  ? 334  LEU C O   1 
ATOM   8219  C CB  . LEU B 2 316 ? 179.416 165.486 93.745  1.00 57.27  ? 334  LEU C CB  1 
ATOM   8220  C CG  . LEU B 2 316 ? 179.729 166.940 93.411  1.00 57.27  ? 334  LEU C CG  1 
ATOM   8221  C CD1 . LEU B 2 316 ? 178.504 167.807 93.624  1.00 57.27  ? 334  LEU C CD1 1 
ATOM   8222  C CD2 . LEU B 2 316 ? 180.890 167.382 94.288  1.00 57.27  ? 334  LEU C CD2 1 
ATOM   8223  N N   . ASP B 2 317 ? 178.893 165.102 90.510  1.00 40.29  ? 335  ASP C N   1 
ATOM   8224  C CA  . ASP B 2 317 ? 179.573 164.878 89.248  1.00 40.29  ? 335  ASP C CA  1 
ATOM   8225  C C   . ASP B 2 317 ? 179.810 166.231 88.537  1.00 40.29  ? 335  ASP C C   1 
ATOM   8226  O O   . ASP B 2 317 ? 179.060 166.586 87.611  1.00 40.29  ? 335  ASP C O   1 
ATOM   8227  C CB  . ASP B 2 317 ? 178.737 163.924 88.401  1.00 51.71  ? 335  ASP C CB  1 
ATOM   8228  C CG  . ASP B 2 317 ? 179.441 163.375 87.192  1.00 51.71  ? 335  ASP C CG  1 
ATOM   8229  O OD1 . ASP B 2 317 ? 180.652 163.165 87.267  1.00 51.71  ? 335  ASP C OD1 1 
ATOM   8230  O OD2 . ASP B 2 317 ? 178.768 163.067 86.233  1.00 51.71  ? 335  ASP C OD2 1 
ATOM   8231  N N   . PRO B 2 318 ? 180.844 166.999 88.978  1.00 40.29  ? 336  PRO C N   1 
ATOM   8232  C CA  . PRO B 2 318 ? 181.234 168.358 88.601  1.00 40.29  ? 336  PRO C CA  1 
ATOM   8233  C C   . PRO B 2 318 ? 181.610 168.526 87.143  1.00 40.29  ? 336  PRO C C   1 
ATOM   8234  O O   . PRO B 2 318 ? 181.965 169.621 86.708  1.00 40.29  ? 336  PRO C O   1 
ATOM   8235  C CB  . PRO B 2 318 ? 182.431 168.648 89.474  1.00 68.85  ? 336  PRO C CB  1 
ATOM   8236  C CG  . PRO B 2 318 ? 182.297 167.720 90.612  1.00 68.85  ? 336  PRO C CG  1 
ATOM   8237  C CD  . PRO B 2 318 ? 181.696 166.482 90.062  1.00 68.85  ? 336  PRO C CD  1 
ATOM   8238  N N   . TRP B 2 319 ? 181.712 167.422 86.424  1.00 44.93  ? 337  TRP C N   1 
ATOM   8239  C CA  . TRP B 2 319 ? 181.945 167.480 85.011  1.00 44.93  ? 337  TRP C CA  1 
ATOM   8240  C C   . TRP B 2 319 ? 180.779 168.243 84.425  1.00 44.93  ? 337  TRP C C   1 
ATOM   8241  O O   . TRP B 2 319 ? 180.948 169.161 83.615  1.00 44.93  ? 337  TRP C O   1 
ATOM   8242  C CB  . TRP B 2 319 ? 182.077 166.074 84.449  1.00 60.15  ? 337  TRP C CB  1 
ATOM   8243  C CG  . TRP B 2 319 ? 182.053 165.957 83.010  1.00 60.15  ? 337  TRP C CG  1 
ATOM   8244  C CD1 . TRP B 2 319 ? 181.160 165.233 82.299  1.00 60.15  ? 337  TRP C CD1 1 
ATOM   8245  C CD2 . TRP B 2 319 ? 182.909 166.584 82.053  1.00 60.15  ? 337  TRP C CD2 1 
ATOM   8246  N NE1 . TRP B 2 319 ? 181.423 165.340 80.976  1.00 60.15  ? 337  TRP C NE1 1 
ATOM   8247  C CE2 . TRP B 2 319 ? 182.491 166.169 80.808  1.00 60.15  ? 337  TRP C CE2 1 
ATOM   8248  C CE3 . TRP B 2 319 ? 183.972 167.449 82.148  1.00 60.15  ? 337  TRP C CE3 1 
ATOM   8249  C CZ2 . TRP B 2 319 ? 183.112 166.584 79.666  1.00 60.15  ? 337  TRP C CZ2 1 
ATOM   8250  C CZ3 . TRP B 2 319 ? 184.603 167.870 81.006  1.00 60.15  ? 337  TRP C CZ3 1 
ATOM   8251  C CH2 . TRP B 2 319 ? 184.188 167.447 79.794  1.00 60.15  ? 337  TRP C CH2 1 
ATOM   8252  N N   . ASN B 2 320 ? 179.580 167.899 84.904  1.00 43.97  ? 338  ASN C N   1 
ATOM   8253  C CA  . ASN B 2 320 ? 178.380 168.548 84.447  1.00 43.97  ? 338  ASN C CA  1 
ATOM   8254  C C   . ASN B 2 320 ? 178.068 169.690 85.397  1.00 43.97  ? 338  ASN C C   1 
ATOM   8255  O O   . ASN B 2 320 ? 177.777 170.817 84.984  1.00 43.97  ? 338  ASN C O   1 
ATOM   8256  C CB  . ASN B 2 320 ? 177.270 167.535 84.408  1.00 58.49  ? 338  ASN C CB  1 
ATOM   8257  C CG  . ASN B 2 320 ? 177.502 166.495 83.347  1.00 58.49  ? 338  ASN C CG  1 
ATOM   8258  O OD1 . ASN B 2 320 ? 178.037 166.764 82.265  1.00 58.49  ? 338  ASN C OD1 1 
ATOM   8259  N ND2 . ASN B 2 320 ? 177.123 165.288 83.651  1.00 58.49  ? 338  ASN C ND2 1 
ATOM   8260  N N   . ASN B 2 321 ? 178.236 169.440 86.692  1.00 40.29  ? 339  ASN C N   1 
ATOM   8261  C CA  . ASN B 2 321 ? 177.956 170.474 87.678  1.00 40.29  ? 339  ASN C CA  1 
ATOM   8262  C C   . ASN B 2 321 ? 179.203 171.331 87.905  1.00 40.29  ? 339  ASN C C   1 
ATOM   8263  O O   . ASN B 2 321 ? 179.832 171.314 88.966  1.00 40.29  ? 339  ASN C O   1 
ATOM   8264  C CB  . ASN B 2 321 ? 177.407 169.844 88.930  1.00 53.59  ? 339  ASN C CB  1 
ATOM   8265  C CG  . ASN B 2 321 ? 176.056 169.238 88.642  1.00 53.59  ? 339  ASN C CG  1 
ATOM   8266  O OD1 . ASN B 2 321 ? 175.249 169.806 87.893  1.00 53.59  ? 339  ASN C OD1 1 
ATOM   8267  N ND2 . ASN B 2 321 ? 175.788 168.100 89.214  1.00 53.59  ? 339  ASN C ND2 1 
ATOM   8268  N N   . SER B 2 322 ? 179.479 172.131 86.886  1.00 40.29  ? 340  SER C N   1 
ATOM   8269  C CA  . SER B 2 322 ? 180.682 172.934 86.644  1.00 40.29  ? 340  SER C CA  1 
ATOM   8270  C C   . SER B 2 322 ? 180.908 174.181 87.502  1.00 40.29  ? 340  SER C C   1 
ATOM   8271  O O   . SER B 2 322 ? 181.959 174.818 87.403  1.00 40.29  ? 340  SER C O   1 
ATOM   8272  C CB  . SER B 2 322 ? 180.672 173.365 85.197  1.00 53.66  ? 340  SER C CB  1 
ATOM   8273  O OG  . SER B 2 322 ? 179.613 174.257 84.955  1.00 53.66  ? 340  SER C OG  1 
ATOM   8274  N N   . ARG B 2 323 ? 179.932 174.560 88.315  1.00 40.29  ? 341  ARG C N   1 
ATOM   8275  C CA  . ARG B 2 323 ? 180.033 175.768 89.136  1.00 40.29  ? 341  ARG C CA  1 
ATOM   8276  C C   . ARG B 2 323 ? 181.344 175.919 89.904  1.00 40.29  ? 341  ARG C C   1 
ATOM   8277  O O   . ARG B 2 323 ? 181.830 177.038 90.056  1.00 40.29  ? 341  ARG C O   1 
ATOM   8278  C CB  . ARG B 2 323 ? 178.894 175.827 90.134  1.00 56.58  ? 341  ARG C CB  1 
ATOM   8279  C CG  . ARG B 2 323 ? 178.931 177.032 91.082  1.00 56.58  ? 341  ARG C CG  1 
ATOM   8280  C CD  . ARG B 2 323 ? 177.759 177.072 91.970  1.00 56.58  ? 341  ARG C CD  1 
ATOM   8281  N NE  . ARG B 2 323 ? 177.709 175.921 92.859  1.00 56.58  ? 341  ARG C NE  1 
ATOM   8282  C CZ  . ARG B 2 323 ? 176.692 175.637 93.704  1.00 56.58  ? 341  ARG C CZ  1 
ATOM   8283  N NH1 . ARG B 2 323 ? 176.718 174.571 94.454  1.00 56.58  ? 341  ARG C NH1 1 
ATOM   8284  N NH2 . ARG B 2 323 ? 175.644 176.400 93.809  1.00 56.58  ? 341  ARG C NH2 1 
ATOM   8285  N N   . ASN B 2 324 ? 181.875 174.833 90.457  1.00 40.29  ? 342  ASN C N   1 
ATOM   8286  C CA  . ASN B 2 324 ? 183.113 174.900 91.205  1.00 40.29  ? 342  ASN C CA  1 
ATOM   8287  C C   . ASN B 2 324 ? 184.316 174.640 90.279  1.00 40.29  ? 342  ASN C C   1 
ATOM   8288  O O   . ASN B 2 324 ? 184.605 173.484 89.945  1.00 40.29  ? 342  ASN C O   1 
ATOM   8289  C CB  . ASN B 2 324 ? 183.056 173.944 92.358  1.00 53.59  ? 342  ASN C CB  1 
ATOM   8290  C CG  . ASN B 2 324 ? 184.306 173.913 93.180  1.00 53.59  ? 342  ASN C CG  1 
ATOM   8291  O OD1 . ASN B 2 324 ? 185.411 174.325 92.756  1.00 53.59  ? 342  ASN C OD1 1 
ATOM   8292  N ND2 . ASN B 2 324 ? 184.168 173.400 94.377  1.00 53.59  ? 342  ASN C ND2 1 
ATOM   8293  N N   . PRO B 2 325 ? 185.107 175.673 89.946  1.00 40.29  ? 343  PRO C N   1 
ATOM   8294  C CA  . PRO B 2 325 ? 186.154 175.674 88.955  1.00 40.29  ? 343  PRO C CA  1 
ATOM   8295  C C   . PRO B 2 325 ? 187.361 174.845 89.313  1.00 40.29  ? 343  PRO C C   1 
ATOM   8296  O O   . PRO B 2 325 ? 188.202 174.586 88.455  1.00 40.29  ? 343  PRO C O   1 
ATOM   8297  C CB  . PRO B 2 325 ? 186.538 177.148 88.885  1.00 68.85  ? 343  PRO C CB  1 
ATOM   8298  C CG  . PRO B 2 325 ? 186.214 177.681 90.225  1.00 68.85  ? 343  PRO C CG  1 
ATOM   8299  C CD  . PRO B 2 325 ? 185.026 176.935 90.676  1.00 68.85  ? 343  PRO C CD  1 
ATOM   8300  N N   . TRP B 2 326 ? 187.485 174.420 90.563  1.00 40.29  ? 344  TRP C N   1 
ATOM   8301  C CA  . TRP B 2 326 ? 188.700 173.705 90.888  1.00 40.29  ? 344  TRP C CA  1 
ATOM   8302  C C   . TRP B 2 326 ? 188.496 172.209 90.809  1.00 40.29  ? 344  TRP C C   1 
ATOM   8303  O O   . TRP B 2 326 ? 189.424 171.421 91.052  1.00 40.29  ? 344  TRP C O   1 
ATOM   8304  C CB  . TRP B 2 326 ? 189.229 174.125 92.242  1.00 53.94  ? 344  TRP C CB  1 
ATOM   8305  C CG  . TRP B 2 326 ? 189.510 175.583 92.281  1.00 53.94  ? 344  TRP C CG  1 
ATOM   8306  C CD1 . TRP B 2 326 ? 190.585 176.227 91.769  1.00 53.94  ? 344  TRP C CD1 1 
ATOM   8307  C CD2 . TRP B 2 326 ? 188.720 176.585 92.926  1.00 53.94  ? 344  TRP C CD2 1 
ATOM   8308  N NE1 . TRP B 2 326 ? 190.496 177.568 92.038  1.00 53.94  ? 344  TRP C NE1 1 
ATOM   8309  C CE2 . TRP B 2 326 ? 189.365 177.796 92.742  1.00 53.94  ? 344  TRP C CE2 1 
ATOM   8310  C CE3 . TRP B 2 326 ? 187.551 176.552 93.642  1.00 53.94  ? 344  TRP C CE3 1 
ATOM   8311  C CZ2 . TRP B 2 326 ? 188.862 178.961 93.244  1.00 53.94  ? 344  TRP C CZ2 1 
ATOM   8312  C CZ3 . TRP B 2 326 ? 187.052 177.712 94.145  1.00 53.94  ? 344  TRP C CZ3 1 
ATOM   8313  C CH2 . TRP B 2 326 ? 187.681 178.895 93.950  1.00 53.94  ? 344  TRP C CH2 1 
ATOM   8314  N N   . PHE B 2 327 ? 187.303 171.802 90.395  1.00 40.29  ? 345  PHE C N   1 
ATOM   8315  C CA  . PHE B 2 327 ? 187.100 170.390 90.266  1.00 40.29  ? 345  PHE C CA  1 
ATOM   8316  C C   . PHE B 2 327 ? 187.864 169.767 89.153  1.00 40.29  ? 345  PHE C C   1 
ATOM   8317  O O   . PHE B 2 327 ? 188.257 168.618 89.266  1.00 40.29  ? 345  PHE C O   1 
ATOM   8318  C CB  . PHE B 2 327 ? 185.661 169.984 90.145  1.00 54.49  ? 345  PHE C CB  1 
ATOM   8319  C CG  . PHE B 2 327 ? 185.062 169.716 91.421  1.00 54.49  ? 345  PHE C CG  1 
ATOM   8320  C CD1 . PHE B 2 327 ? 185.419 168.571 92.110  1.00 54.49  ? 345  PHE C CD1 1 
ATOM   8321  C CD2 . PHE B 2 327 ? 184.153 170.521 91.933  1.00 54.49  ? 345  PHE C CD2 1 
ATOM   8322  C CE1 . PHE B 2 327 ? 184.859 168.270 93.305  1.00 54.49  ? 345  PHE C CE1 1 
ATOM   8323  C CE2 . PHE B 2 327 ? 183.568 170.237 93.142  1.00 54.49  ? 345  PHE C CE2 1 
ATOM   8324  C CZ  . PHE B 2 327 ? 183.931 169.107 93.828  1.00 54.49  ? 345  PHE C CZ  1 
ATOM   8325  N N   . ARG B 2 328 ? 188.179 170.478 88.090  1.00 40.29  ? 346  ARG C N   1 
ATOM   8326  C CA  . ARG B 2 328 ? 188.873 169.746 87.054  1.00 40.29  ? 346  ARG C CA  1 
ATOM   8327  C C   . ARG B 2 328 ? 190.172 169.142 87.612  1.00 40.29  ? 346  ARG C C   1 
ATOM   8328  O O   . ARG B 2 328 ? 190.451 167.967 87.363  1.00 40.29  ? 346  ARG C O   1 
ATOM   8329  C CB  . ARG B 2 328 ? 189.134 170.650 85.853  1.00 56.58  ? 346  ARG C CB  1 
ATOM   8330  C CG  . ARG B 2 328 ? 187.841 171.135 85.098  1.00 56.58  ? 346  ARG C CG  1 
ATOM   8331  C CD  . ARG B 2 328 ? 187.196 170.019 84.345  1.00 56.58  ? 346  ARG C CD  1 
ATOM   8332  N NE  . ARG B 2 328 ? 185.992 170.387 83.602  1.00 56.58  ? 346  ARG C NE  1 
ATOM   8333  C CZ  . ARG B 2 328 ? 184.718 170.307 84.077  1.00 56.58  ? 346  ARG C CZ  1 
ATOM   8334  N NH1 . ARG B 2 328 ? 183.697 170.579 83.261  1.00 56.58  ? 346  ARG C NH1 1 
ATOM   8335  N NH2 . ARG B 2 328 ? 184.496 169.937 85.324  1.00 56.58  ? 346  ARG C NH2 1 
ATOM   8336  N N   . GLU B 2 329 ? 190.916 169.883 88.449  1.00 40.29  ? 347  GLU C N   1 
ATOM   8337  C CA  . GLU B 2 329 ? 192.117 169.280 89.017  1.00 40.29  ? 347  GLU C CA  1 
ATOM   8338  C C   . GLU B 2 329 ? 191.763 168.153 89.970  1.00 40.29  ? 347  GLU C C   1 
ATOM   8339  O O   . GLU B 2 329 ? 192.434 167.115 89.981  1.00 40.29  ? 347  GLU C O   1 
ATOM   8340  C CB  . GLU B 2 329 ? 193.001 170.270 89.761  1.00 53.10  ? 347  GLU C CB  1 
ATOM   8341  C CG  . GLU B 2 329 ? 194.267 169.579 90.325  1.00 53.10  ? 347  GLU C CG  1 
ATOM   8342  C CD  . GLU B 2 329 ? 195.238 170.488 90.936  1.00 53.10  ? 347  GLU C CD  1 
ATOM   8343  O OE1 . GLU B 2 329 ? 195.395 171.573 90.453  1.00 53.10  ? 347  GLU C OE1 1 
ATOM   8344  O OE2 . GLU B 2 329 ? 195.839 170.106 91.921  1.00 53.10  ? 347  GLU C OE2 1 
ATOM   8345  N N   . PHE B 2 330 ? 190.725 168.367 90.782  1.00 40.29  ? 348  PHE C N   1 
ATOM   8346  C CA  . PHE B 2 330 ? 190.303 167.391 91.769  1.00 40.29  ? 348  PHE C CA  1 
ATOM   8347  C C   . PHE B 2 330 ? 190.016 166.070 91.092  1.00 40.29  ? 348  PHE C C   1 
ATOM   8348  O O   . PHE B 2 330 ? 190.476 165.026 91.535  1.00 40.29  ? 348  PHE C O   1 
ATOM   8349  C CB  . PHE B 2 330 ? 189.028 167.855 92.421  1.00 54.49  ? 348  PHE C CB  1 
ATOM   8350  C CG  . PHE B 2 330 ? 188.487 167.008 93.507  1.00 54.49  ? 348  PHE C CG  1 
ATOM   8351  C CD1 . PHE B 2 330 ? 188.880 167.227 94.808  1.00 54.49  ? 348  PHE C CD1 1 
ATOM   8352  C CD2 . PHE B 2 330 ? 187.587 165.991 93.258  1.00 54.49  ? 348  PHE C CD2 1 
ATOM   8353  C CE1 . PHE B 2 330 ? 188.379 166.474 95.832  1.00 54.49  ? 348  PHE C CE1 1 
ATOM   8354  C CE2 . PHE B 2 330 ? 187.100 165.232 94.298  1.00 54.49  ? 348  PHE C CE2 1 
ATOM   8355  C CZ  . PHE B 2 330 ? 187.495 165.480 95.577  1.00 54.49  ? 348  PHE C CZ  1 
ATOM   8356  N N   . TRP B 2 331 ? 189.252 166.103 90.007  1.00 40.29  ? 349  TRP C N   1 
ATOM   8357  C CA  . TRP B 2 331 ? 188.884 164.894 89.290  1.00 40.29  ? 349  TRP C CA  1 
ATOM   8358  C C   . TRP B 2 331 ? 190.070 164.139 88.809  1.00 40.29  ? 349  TRP C C   1 
ATOM   8359  O O   . TRP B 2 331 ? 190.147 162.931 89.021  1.00 40.29  ? 349  TRP C O   1 
ATOM   8360  C CB  . TRP B 2 331 ? 188.137 165.242 88.043  1.00 53.89  ? 349  TRP C CB  1 
ATOM   8361  C CG  . TRP B 2 331 ? 186.722 165.441 88.147  1.00 53.89  ? 349  TRP C CG  1 
ATOM   8362  C CD1 . TRP B 2 331 ? 186.070 166.408 88.771  1.00 53.89  ? 349  TRP C CD1 1 
ATOM   8363  C CD2 . TRP B 2 331 ? 185.743 164.667 87.510  1.00 53.89  ? 349  TRP C CD2 1 
ATOM   8364  N NE1 . TRP B 2 331 ? 184.761 166.282 88.570  1.00 53.89  ? 349  TRP C NE1 1 
ATOM   8365  C CE2 . TRP B 2 331 ? 184.543 165.236 87.791  1.00 53.89  ? 349  TRP C CE2 1 
ATOM   8366  C CE3 . TRP B 2 331 ? 185.783 163.566 86.724  1.00 53.89  ? 349  TRP C CE3 1 
ATOM   8367  C CZ2 . TRP B 2 331 ? 183.391 164.737 87.307  1.00 53.89  ? 349  TRP C CZ2 1 
ATOM   8368  C CZ3 . TRP B 2 331 ? 184.625 163.097 86.234  1.00 53.89  ? 349  TRP C CZ3 1 
ATOM   8369  C CH2 . TRP B 2 331 ? 183.474 163.656 86.511  1.00 53.89  ? 349  TRP C CH2 1 
ATOM   8370  N N   . GLU B 2 332 ? 191.019 164.865 88.216  1.00 43.09  ? 350  GLU C N   1 
ATOM   8371  C CA  . GLU B 2 332 ? 192.217 164.281 87.634  1.00 43.09  ? 350  GLU C CA  1 
ATOM   8372  C C   . GLU B 2 332 ? 193.084 163.580 88.655  1.00 43.09  ? 350  GLU C C   1 
ATOM   8373  O O   . GLU B 2 332 ? 193.734 162.569 88.357  1.00 43.09  ? 350  GLU C O   1 
ATOM   8374  C CB  . GLU B 2 332 ? 193.018 165.372 86.933  1.00 56.79  ? 350  GLU C CB  1 
ATOM   8375  C CG  . GLU B 2 332 ? 192.345 165.914 85.686  1.00 56.79  ? 350  GLU C CG  1 
ATOM   8376  C CD  . GLU B 2 332 ? 193.115 167.009 85.019  1.00 56.79  ? 350  GLU C CD  1 
ATOM   8377  O OE1 . GLU B 2 332 ? 193.971 167.556 85.664  1.00 56.79  ? 350  GLU C OE1 1 
ATOM   8378  O OE2 . GLU B 2 332 ? 192.893 167.264 83.843  1.00 56.79  ? 350  GLU C OE2 1 
ATOM   8379  N N   . GLN B 2 333 ? 193.126 164.119 89.868  1.00 42.38  ? 351  GLN C N   1 
ATOM   8380  C CA  . GLN B 2 333 ? 193.937 163.486 90.881  1.00 42.38  ? 351  GLN C CA  1 
ATOM   8381  C C   . GLN B 2 333 ? 193.153 162.522 91.786  1.00 42.38  ? 351  GLN C C   1 
ATOM   8382  O O   . GLN B 2 333 ? 193.751 161.604 92.353  1.00 42.38  ? 351  GLN C O   1 
ATOM   8383  C CB  . GLN B 2 333 ? 194.636 164.555 91.710  1.00 57.60  ? 351  GLN C CB  1 
ATOM   8384  C CG  . GLN B 2 333 ? 195.536 165.451 90.883  1.00 57.60  ? 351  GLN C CG  1 
ATOM   8385  C CD  . GLN B 2 333 ? 196.590 164.676 90.135  1.00 57.60  ? 351  GLN C CD  1 
ATOM   8386  O OE1 . GLN B 2 333 ? 197.344 163.881 90.705  1.00 57.60  ? 351  GLN C OE1 1 
ATOM   8387  N NE2 . GLN B 2 333 ? 196.642 164.902 88.833  1.00 57.60  ? 351  GLN C NE2 1 
ATOM   8388  N N   . ARG B 2 334 ? 191.830 162.714 91.924  1.00 46.92  ? 352  ARG C N   1 
ATOM   8389  C CA  . ARG B 2 334 ? 191.014 161.859 92.783  1.00 46.92  ? 352  ARG C CA  1 
ATOM   8390  C C   . ARG B 2 334 ? 190.808 160.513 92.108  1.00 46.92  ? 352  ARG C C   1 
ATOM   8391  O O   . ARG B 2 334 ? 190.887 159.459 92.743  1.00 46.92  ? 352  ARG C O   1 
ATOM   8392  C CB  . ARG B 2 334 ? 189.657 162.509 93.080  1.00 65.90  ? 352  ARG C CB  1 
ATOM   8393  C CG  . ARG B 2 334 ? 188.729 161.720 94.017  1.00 65.90  ? 352  ARG C CG  1 
ATOM   8394  C CD  . ARG B 2 334 ? 189.322 161.588 95.395  1.00 65.90  ? 352  ARG C CD  1 
ATOM   8395  N NE  . ARG B 2 334 ? 188.537 160.749 96.298  1.00 65.90  ? 352  ARG C NE  1 
ATOM   8396  C CZ  . ARG B 2 334 ? 189.021 160.243 97.466  1.00 65.90  ? 352  ARG C CZ  1 
ATOM   8397  N NH1 . ARG B 2 334 ? 188.287 159.436 98.225  1.00 65.90  ? 352  ARG C NH1 1 
ATOM   8398  N NH2 . ARG B 2 334 ? 190.253 160.545 97.859  1.00 65.90  ? 352  ARG C NH2 1 
ATOM   8399  N N   . PHE B 2 335 ? 190.547 160.559 90.813  1.00 50.59  ? 353  PHE C N   1 
ATOM   8400  C CA  . PHE B 2 335 ? 190.411 159.392 89.980  1.00 50.59  ? 353  PHE C CA  1 
ATOM   8401  C C   . PHE B 2 335 ? 191.675 159.516 89.155  1.00 50.59  ? 353  PHE C C   1 
ATOM   8402  O O   . PHE B 2 335 ? 191.989 160.615 88.726  1.00 50.59  ? 353  PHE C O   1 
ATOM   8403  C CB  . PHE B 2 335 ? 189.174 159.470 89.073  1.00 68.42  ? 353  PHE C CB  1 
ATOM   8404  C CG  . PHE B 2 335 ? 188.985 158.235 88.270  1.00 68.42  ? 353  PHE C CG  1 
ATOM   8405  C CD1 . PHE B 2 335 ? 189.725 158.043 87.155  1.00 68.42  ? 353  PHE C CD1 1 
ATOM   8406  C CD2 . PHE B 2 335 ? 188.122 157.229 88.668  1.00 68.42  ? 353  PHE C CD2 1 
ATOM   8407  C CE1 . PHE B 2 335 ? 189.640 156.905 86.435  1.00 68.42  ? 353  PHE C CE1 1 
ATOM   8408  C CE2 . PHE B 2 335 ? 188.014 156.082 87.950  1.00 68.42  ? 353  PHE C CE2 1 
ATOM   8409  C CZ  . PHE B 2 335 ? 188.779 155.914 86.830  1.00 68.42  ? 353  PHE C CZ  1 
ATOM   8410  N N   . ARG B 2 336 ? 192.429 158.470 88.881  1.00 55.78  ? 354  ARG C N   1 
ATOM   8411  C CA  . ARG B 2 336 ? 193.605 158.835 88.104  1.00 55.78  ? 354  ARG C CA  1 
ATOM   8412  C C   . ARG B 2 336 ? 193.242 158.886 86.612  1.00 55.78  ? 354  ARG C C   1 
ATOM   8413  O O   . ARG B 2 336 ? 193.093 157.845 85.964  1.00 55.78  ? 354  ARG C O   1 
ATOM   8414  C CB  . ARG B 2 336 ? 194.738 157.855 88.341  1.00 78.34  ? 354  ARG C CB  1 
ATOM   8415  C CG  . ARG B 2 336 ? 196.066 158.240 87.691  1.00 78.34  ? 354  ARG C CG  1 
ATOM   8416  C CD  . ARG B 2 336 ? 196.713 159.384 88.412  1.00 78.34  ? 354  ARG C CD  1 
ATOM   8417  N NE  . ARG B 2 336 ? 198.035 159.671 87.897  1.00 78.34  ? 354  ARG C NE  1 
ATOM   8418  C CZ  . ARG B 2 336 ? 198.854 160.637 88.368  1.00 78.34  ? 354  ARG C CZ  1 
ATOM   8419  N NH1 . ARG B 2 336 ? 200.046 160.807 87.818  1.00 78.34  ? 354  ARG C NH1 1 
ATOM   8420  N NH2 . ARG B 2 336 ? 198.477 161.407 89.372  1.00 78.34  ? 354  ARG C NH2 1 
ATOM   8421  N N   . CYS B 2 337 ? 193.111 160.127 86.091  1.00 58.38  ? 355  CYS C N   1 
ATOM   8422  C CA  . CYS B 2 337 ? 192.660 160.465 84.733  1.00 58.38  ? 355  CYS C CA  1 
ATOM   8423  C C   . CYS B 2 337 ? 193.176 161.842 84.302  1.00 58.38  ? 355  CYS C C   1 
ATOM   8424  O O   . CYS B 2 337 ? 194.026 162.438 84.951  1.00 58.38  ? 355  CYS C O   1 
ATOM   8425  C CB  . CYS B 2 337 ? 191.118 160.385 84.621  1.00 75.65  ? 355  CYS C CB  1 
ATOM   8426  S SG  . CYS B 2 337 ? 190.179 161.520 85.715  1.00 75.65  ? 355  CYS C SG  1 
ATOM   8427  N N   . SER B 2 338 ? 192.707 162.287 83.134  1.00 64.02  ? 356  SER C N   1 
ATOM   8428  C CA  . SER B 2 338 ? 193.040 163.600 82.592  1.00 64.02  ? 356  SER C CA  1 
ATOM   8429  C C   . SER B 2 338 ? 191.880 164.204 81.797  1.00 64.02  ? 356  SER C C   1 
ATOM   8430  O O   . SER B 2 338 ? 191.222 163.509 81.012  1.00 64.02  ? 356  SER C O   1 
ATOM   8431  C CB  . SER B 2 338 ? 194.249 163.520 81.703  1.00 85.27  ? 356  SER C CB  1 
ATOM   8432  O OG  . SER B 2 338 ? 194.486 164.761 81.089  1.00 85.27  ? 356  SER C OG  1 
ATOM   8433  N N   . PHE B 2 339 ? 191.639 165.509 81.941  1.00 57.95  ? 357  PHE C N   1 
ATOM   8434  C CA  . PHE B 2 339 ? 190.623 166.124 81.094  1.00 57.95  ? 357  PHE C CA  1 
ATOM   8435  C C   . PHE B 2 339 ? 191.186 166.679 79.798  1.00 57.95  ? 357  PHE C C   1 
ATOM   8436  O O   . PHE B 2 339 ? 190.423 167.116 78.943  1.00 57.95  ? 357  PHE C O   1 
ATOM   8437  C CB  . PHE B 2 339 ? 189.814 167.232 81.782  1.00 78.37  ? 357  PHE C CB  1 
ATOM   8438  C CG  . PHE B 2 339 ? 188.691 166.789 82.685  1.00 78.37  ? 357  PHE C CG  1 
ATOM   8439  C CD1 . PHE B 2 339 ? 187.555 166.220 82.111  1.00 78.37  ? 357  PHE C CD1 1 
ATOM   8440  C CD2 . PHE B 2 339 ? 188.712 166.950 84.064  1.00 78.37  ? 357  PHE C CD2 1 
ATOM   8441  C CE1 . PHE B 2 339 ? 186.500 165.826 82.886  1.00 78.37  ? 357  PHE C CE1 1 
ATOM   8442  C CE2 . PHE B 2 339 ? 187.618 166.567 84.812  1.00 78.37  ? 357  PHE C CE2 1 
ATOM   8443  C CZ  . PHE B 2 339 ? 186.520 166.010 84.225  1.00 78.37  ? 357  PHE C CZ  1 
ATOM   8444  N N   . ARG B 2 340 ? 192.499 166.594 79.584  1.00 68.49  ? 358  ARG C N   1 
ATOM   8445  C CA  . ARG B 2 340 ? 193.084 167.154 78.360  1.00 68.49  ? 358  ARG C CA  1 
ATOM   8446  C C   . ARG B 2 340 ? 192.493 166.510 77.104  1.00 68.49  ? 358  ARG C C   1 
ATOM   8447  O O   . ARG B 2 340 ? 192.295 167.170 76.084  1.00 68.49  ? 358  ARG C O   1 
ATOM   8448  C CB  . ARG B 2 340 ? 194.595 166.995 78.356  1.00 96.19  ? 358  ARG C CB  1 
ATOM   8449  C CG  . ARG B 2 340 ? 195.299 167.647 77.166  1.00 96.19  ? 358  ARG C CG  1 
ATOM   8450  C CD  . ARG B 2 340 ? 196.785 167.641 77.318  1.00 96.19  ? 358  ARG C CD  1 
ATOM   8451  N NE  . ARG B 2 340 ? 197.342 166.289 77.274  1.00 96.19  ? 358  ARG C NE  1 
ATOM   8452  C CZ  . ARG B 2 340 ? 198.597 165.943 77.642  1.00 96.19  ? 358  ARG C CZ  1 
ATOM   8453  N NH1 . ARG B 2 340 ? 198.978 164.681 77.536  1.00 96.19  ? 358  ARG C NH1 1 
ATOM   8454  N NH2 . ARG B 2 340 ? 199.443 166.850 78.102  1.00 96.19  ? 358  ARG C NH2 1 
ATOM   8455  N N   . GLN B 2 341 ? 192.242 165.207 77.186  1.00 71.67  ? 359  GLN C N   1 
ATOM   8456  C CA  . GLN B 2 341 ? 191.668 164.403 76.119  1.00 71.67  ? 359  GLN C CA  1 
ATOM   8457  C C   . GLN B 2 341 ? 190.234 164.035 76.444  1.00 71.67  ? 359  GLN C C   1 
ATOM   8458  O O   . GLN B 2 341 ? 189.686 163.125 75.825  1.00 71.67  ? 359  GLN C O   1 
ATOM   8459  C CB  . GLN B 2 341 ? 192.408 163.083 75.924  1.00 97.41  ? 359  GLN C CB  1 
ATOM   8460  C CG  . GLN B 2 341 ? 193.798 163.149 75.374  1.00 97.41  ? 359  GLN C CG  1 
ATOM   8461  C CD  . GLN B 2 341 ? 194.835 163.489 76.404  1.00 97.41  ? 359  GLN C CD  1 
ATOM   8462  O OE1 . GLN B 2 341 ? 195.630 164.412 76.174  1.00 97.41  ? 359  GLN C OE1 1 
ATOM   8463  N NE2 . GLN B 2 341 ? 194.851 162.768 77.535  1.00 97.41  ? 359  GLN C NE2 1 
ATOM   8464  N N   . ARG B 2 342 ? 189.648 164.679 77.455  1.00 71.31  ? 360  ARG C N   1 
ATOM   8465  C CA  . ARG B 2 342 ? 188.335 164.302 77.954  1.00 71.31  ? 360  ARG C CA  1 
ATOM   8466  C C   . ARG B 2 342 ? 188.328 162.841 78.419  1.00 71.31  ? 360  ARG C C   1 
ATOM   8467  O O   . ARG B 2 342 ? 187.363 162.120 78.158  1.00 71.31  ? 360  ARG C O   1 
ATOM   8468  C CB  . ARG B 2 342 ? 187.266 164.470 76.874  1.00 104.25 ? 360  ARG C CB  1 
ATOM   8469  C CG  . ARG B 2 342 ? 187.091 165.867 76.331  1.00 104.25 ? 360  ARG C CG  1 
ATOM   8470  C CD  . ARG B 2 342 ? 186.177 165.870 75.147  1.00 104.25 ? 360  ARG C CD  1 
ATOM   8471  N NE  . ARG B 2 342 ? 184.792 165.501 75.457  1.00 104.25 ? 360  ARG C NE  1 
ATOM   8472  C CZ  . ARG B 2 342 ? 183.826 166.334 75.898  1.00 104.25 ? 360  ARG C CZ  1 
ATOM   8473  N NH1 . ARG B 2 342 ? 182.610 165.858 76.112  1.00 104.25 ? 360  ARG C NH1 1 
ATOM   8474  N NH2 . ARG B 2 342 ? 184.077 167.612 76.106  1.00 104.25 ? 360  ARG C NH2 1 
ATOM   8475  N N   . ASP B 2 343 ? 189.383 162.391 79.130  1.00 68.34  ? 361  ASP C N   1 
ATOM   8476  C CA  . ASP B 2 343 ? 189.384 161.009 79.624  1.00 68.34  ? 361  ASP C CA  1 
ATOM   8477  C C   . ASP B 2 343 ? 188.647 160.903 80.967  1.00 68.34  ? 361  ASP C C   1 
ATOM   8478  O O   . ASP B 2 343 ? 187.897 159.955 81.167  1.00 68.34  ? 361  ASP C O   1 
ATOM   8479  C CB  . ASP B 2 343 ? 190.811 160.462 79.829  1.00 87.02  ? 361  ASP C CB  1 
ATOM   8480  C CG  . ASP B 2 343 ? 191.659 160.309 78.561  1.00 87.02  ? 361  ASP C CG  1 
ATOM   8481  O OD1 . ASP B 2 343 ? 191.238 159.659 77.632  1.00 87.02  ? 361  ASP C OD1 1 
ATOM   8482  O OD2 . ASP B 2 343 ? 192.767 160.831 78.566  1.00 87.02  ? 361  ASP C OD2 1 
ATOM   8483  N N   . CYS B 2 344 ? 188.749 161.952 81.842  1.00 65.00  ? 362  CYS C N   1 
ATOM   8484  C CA  . CYS B 2 344 ? 188.073 162.034 83.146  1.00 65.00  ? 362  CYS C CA  1 
ATOM   8485  C C   . CYS B 2 344 ? 186.582 162.138 82.913  1.00 65.00  ? 362  CYS C C   1 
ATOM   8486  O O   . CYS B 2 344 ? 185.775 161.653 83.694  1.00 65.00  ? 362  CYS C O   1 
ATOM   8487  C CB  . CYS B 2 344 ? 188.526 163.254 83.982  1.00 84.23  ? 362  CYS C CB  1 
ATOM   8488  S SG  . CYS B 2 344 ? 190.081 163.246 84.661  1.00 84.23  ? 362  CYS C SG  1 
ATOM   8489  N N   . ALA B 2 345 ? 186.214 162.661 81.763  1.00 60.95  ? 363  ALA C N   1 
ATOM   8490  C CA  . ALA B 2 345 ? 184.825 162.811 81.390  1.00 60.95  ? 363  ALA C CA  1 
ATOM   8491  C C   . ALA B 2 345 ? 184.131 161.444 81.379  1.00 60.95  ? 363  ALA C C   1 
ATOM   8492  O O   . ALA B 2 345 ? 182.919 161.354 81.572  1.00 60.95  ? 363  ALA C O   1 
ATOM   8493  C CB  . ALA B 2 345 ? 184.728 163.473 80.030  1.00 82.34  ? 363  ALA C CB  1 
ATOM   8494  N N   . ALA B 2 346 ? 184.894 160.371 81.109  1.00 67.54  ? 364  ALA C N   1 
ATOM   8495  C CA  . ALA B 2 346 ? 184.383 159.012 81.036  1.00 67.54  ? 364  ALA C CA  1 
ATOM   8496  C C   . ALA B 2 346 ? 184.360 158.317 82.397  1.00 67.54  ? 364  ALA C C   1 
ATOM   8497  O O   . ALA B 2 346 ? 183.934 157.163 82.504  1.00 67.54  ? 364  ALA C O   1 
ATOM   8498  C CB  . ALA B 2 346 ? 185.242 158.200 80.089  1.00 91.24  ? 364  ALA C CB  1 
ATOM   8499  N N   . HIS B 2 347 ? 184.838 158.990 83.432  1.00 66.46  ? 365  HIS C N   1 
ATOM   8500  C CA  . HIS B 2 347 ? 184.938 158.397 84.749  1.00 66.46  ? 365  HIS C CA  1 
ATOM   8501  C C   . HIS B 2 347 ? 184.254 159.279 85.748  1.00 66.46  ? 365  HIS C C   1 
ATOM   8502  O O   . HIS B 2 347 ? 184.898 160.102 86.390  1.00 66.46  ? 365  HIS C O   1 
ATOM   8503  C CB  . HIS B 2 347 ? 186.391 158.267 85.159  1.00 88.27  ? 365  HIS C CB  1 
ATOM   8504  C CG  . HIS B 2 347 ? 187.187 157.523 84.201  1.00 88.27  ? 365  HIS C CG  1 
ATOM   8505  N ND1 . HIS B 2 347 ? 187.025 156.180 83.978  1.00 88.27  ? 365  HIS C ND1 1 
ATOM   8506  C CD2 . HIS B 2 347 ? 188.193 157.920 83.408  1.00 88.27  ? 365  HIS C CD2 1 
ATOM   8507  C CE1 . HIS B 2 347 ? 187.891 155.786 83.073  1.00 88.27  ? 365  HIS C CE1 1 
ATOM   8508  N NE2 . HIS B 2 347 ? 188.619 156.823 82.713  1.00 88.27  ? 365  HIS C NE2 1 
ATOM   8509  N N   . SER B 2 348 ? 182.959 159.072 85.924  1.00 59.05  ? 366  SER C N   1 
ATOM   8510  C CA  . SER B 2 348 ? 182.147 159.969 86.729  1.00 59.05  ? 366  SER C CA  1 
ATOM   8511  C C   . SER B 2 348 ? 182.813 160.111 88.077  1.00 59.05  ? 366  SER C C   1 
ATOM   8512  O O   . SER B 2 348 ? 183.379 159.153 88.602  1.00 59.05  ? 366  SER C O   1 
ATOM   8513  C CB  . SER B 2 348 ? 180.754 159.405 86.876  1.00 78.65  ? 366  SER C CB  1 
ATOM   8514  O OG  . SER B 2 348 ? 180.133 159.256 85.627  1.00 78.65  ? 366  SER C OG  1 
ATOM   8515  N N   . LEU B 2 349 ? 182.744 161.295 88.684  1.00 45.41  ? 367  LEU C N   1 
ATOM   8516  C CA  . LEU B 2 349 ? 183.516 161.486 89.922  1.00 45.41  ? 367  LEU C CA  1 
ATOM   8517  C C   . LEU B 2 349 ? 183.143 160.480 90.998  1.00 45.41  ? 367  LEU C C   1 
ATOM   8518  O O   . LEU B 2 349 ? 184.014 159.986 91.728  1.00 45.41  ? 367  LEU C O   1 
ATOM   8519  C CB  . LEU B 2 349 ? 183.353 162.896 90.493  1.00 64.54  ? 367  LEU C CB  1 
ATOM   8520  C CG  . LEU B 2 349 ? 184.266 163.279 91.699  1.00 64.54  ? 367  LEU C CG  1 
ATOM   8521  C CD1 . LEU B 2 349 ? 185.775 163.198 91.277  1.00 64.54  ? 367  LEU C CD1 1 
ATOM   8522  C CD2 . LEU B 2 349 ? 183.901 164.700 92.151  1.00 64.54  ? 367  LEU C CD2 1 
ATOM   8523  N N   . ARG B 2 350 ? 181.865 160.100 91.014  1.00 48.20  ? 368  ARG C N   1 
ATOM   8524  C CA  . ARG B 2 350 ? 181.261 159.164 91.958  1.00 48.20  ? 368  ARG C CA  1 
ATOM   8525  C C   . ARG B 2 350 ? 181.880 157.766 91.903  1.00 48.20  ? 368  ARG C C   1 
ATOM   8526  O O   . ARG B 2 350 ? 181.598 156.921 92.752  1.00 48.20  ? 368  ARG C O   1 
ATOM   8527  C CB  . ARG B 2 350 ? 179.768 159.069 91.695  1.00 67.69  ? 368  ARG C CB  1 
ATOM   8528  C CG  . ARG B 2 350 ? 179.364 158.406 90.391  1.00 67.69  ? 368  ARG C CG  1 
ATOM   8529  C CD  . ARG B 2 350 ? 177.889 158.272 90.306  1.00 67.69  ? 368  ARG C CD  1 
ATOM   8530  N NE  . ARG B 2 350 ? 177.241 159.585 90.233  1.00 67.69  ? 368  ARG C NE  1 
ATOM   8531  C CZ  . ARG B 2 350 ? 176.908 160.267 89.115  1.00 67.69  ? 368  ARG C CZ  1 
ATOM   8532  N NH1 . ARG B 2 350 ? 176.354 161.459 89.246  1.00 67.69  ? 368  ARG C NH1 1 
ATOM   8533  N NH2 . ARG B 2 350 ? 177.124 159.770 87.913  1.00 67.69  ? 368  ARG C NH2 1 
ATOM   8534  N N   . ALA B 2 351 ? 182.674 157.510 90.866  1.00 56.04  ? 369  ALA C N   1 
ATOM   8535  C CA  . ALA B 2 351 ? 183.386 156.268 90.670  1.00 56.04  ? 369  ALA C CA  1 
ATOM   8536  C C   . ALA B 2 351 ? 184.367 156.023 91.813  1.00 56.04  ? 369  ALA C C   1 
ATOM   8537  O O   . ALA B 2 351 ? 184.676 154.876 92.137  1.00 56.04  ? 369  ALA C O   1 
ATOM   8538  C CB  . ALA B 2 351 ? 184.145 156.310 89.349  1.00 75.71  ? 369  ALA C CB  1 
ATOM   8539  N N   . VAL B 2 352 ? 184.910 157.098 92.390  1.00 52.42  ? 370  VAL C N   1 
ATOM   8540  C CA  . VAL B 2 352 ? 185.875 156.959 93.457  1.00 52.42  ? 370  VAL C CA  1 
ATOM   8541  C C   . VAL B 2 352 ? 185.102 157.007 94.787  1.00 52.42  ? 370  VAL C C   1 
ATOM   8542  O O   . VAL B 2 352 ? 184.310 157.929 94.976  1.00 52.42  ? 370  VAL C O   1 
ATOM   8543  C CB  . VAL B 2 352 ? 186.912 158.091 93.427  1.00 73.82  ? 370  VAL C CB  1 
ATOM   8544  C CG1 . VAL B 2 352 ? 187.929 157.889 94.558  1.00 73.82  ? 370  VAL C CG1 1 
ATOM   8545  C CG2 . VAL B 2 352 ? 187.558 158.143 92.095  1.00 73.82  ? 370  VAL C CG2 1 
ATOM   8546  N N   . PRO B 2 353 ? 185.284 156.055 95.715  1.00 44.90  ? 371  PRO C N   1 
ATOM   8547  C CA  . PRO B 2 353 ? 184.631 156.036 97.014  1.00 44.90  ? 371  PRO C CA  1 
ATOM   8548  C C   . PRO B 2 353 ? 184.893 157.328 97.782  1.00 44.90  ? 371  PRO C C   1 
ATOM   8549  O O   . PRO B 2 353 ? 186.010 157.860 97.761  1.00 44.90  ? 371  PRO C O   1 
ATOM   8550  C CB  . PRO B 2 353 ? 185.317 154.848 97.703  1.00 76.72  ? 371  PRO C CB  1 
ATOM   8551  C CG  . PRO B 2 353 ? 185.728 153.942 96.569  1.00 76.72  ? 371  PRO C CG  1 
ATOM   8552  C CD  . PRO B 2 353 ? 186.125 154.872 95.441  1.00 76.72  ? 371  PRO C CD  1 
ATOM   8553  N N   . PHE B 2 354 ? 183.873 157.815 98.471  1.00 40.29  ? 372  PHE C N   1 
ATOM   8554  C CA  . PHE B 2 354 ? 183.948 159.054 99.232  1.00 40.29  ? 372  PHE C CA  1 
ATOM   8555  C C   . PHE B 2 354 ? 183.960 158.885 100.739 1.00 40.29  ? 372  PHE C C   1 
ATOM   8556  O O   . PHE B 2 354 ? 183.188 158.114 101.313 1.00 40.29  ? 372  PHE C O   1 
ATOM   8557  C CB  . PHE B 2 354 ? 182.761 159.955 98.888  1.00 54.49  ? 372  PHE C CB  1 
ATOM   8558  C CG  . PHE B 2 354 ? 182.768 161.209 99.634  1.00 54.49  ? 372  PHE C CG  1 
ATOM   8559  C CD1 . PHE B 2 354 ? 183.553 162.242 99.219  1.00 54.49  ? 372  PHE C CD1 1 
ATOM   8560  C CD2 . PHE B 2 354 ? 182.016 161.361 100.774 1.00 54.49  ? 372  PHE C CD2 1 
ATOM   8561  C CE1 . PHE B 2 354 ? 183.586 163.404 99.915  1.00 54.49  ? 372  PHE C CE1 1 
ATOM   8562  C CE2 . PHE B 2 354 ? 182.065 162.519 101.461 1.00 54.49  ? 372  PHE C CE2 1 
ATOM   8563  C CZ  . PHE B 2 354 ? 182.845 163.548 101.025 1.00 54.49  ? 372  PHE C CZ  1 
ATOM   8564  N N   . GLU B 2 355 ? 184.802 159.679 101.385 1.00 40.29  ? 373  GLU C N   1 
ATOM   8565  C CA  . GLU B 2 355 ? 184.867 159.772 102.826 1.00 40.29  ? 373  GLU C CA  1 
ATOM   8566  C C   . GLU B 2 355 ? 185.031 161.237 103.165 1.00 40.29  ? 373  GLU C C   1 
ATOM   8567  O O   . GLU B 2 355 ? 185.588 161.998 102.376 1.00 40.29  ? 373  GLU C O   1 
ATOM   8568  C CB  . GLU B 2 355 ? 186.041 158.976 103.383 1.00 52.43  ? 373  GLU C CB  1 
ATOM   8569  C CG  . GLU B 2 355 ? 187.410 159.505 102.961 1.00 52.43  ? 373  GLU C CG  1 
ATOM   8570  C CD  . GLU B 2 355 ? 188.547 158.671 103.474 1.00 52.43  ? 373  GLU C CD  1 
ATOM   8571  O OE1 . GLU B 2 355 ? 188.706 158.590 104.669 1.00 52.43  ? 373  GLU C OE1 1 
ATOM   8572  O OE2 . GLU B 2 355 ? 189.259 158.115 102.671 1.00 52.43  ? 373  GLU C OE2 1 
ATOM   8573  N N   . GLN B 2 356 ? 184.609 161.621 104.358 1.00 40.29  ? 374  GLN C N   1 
ATOM   8574  C CA  . GLN B 2 356 ? 184.737 163.002 104.792 1.00 40.29  ? 374  GLN C CA  1 
ATOM   8575  C C   . GLN B 2 356 ? 185.213 163.098 106.206 1.00 40.29  ? 374  GLN C C   1 
ATOM   8576  O O   . GLN B 2 356 ? 184.952 162.211 107.016 1.00 40.29  ? 374  GLN C O   1 
ATOM   8577  C CB  . GLN B 2 356 ? 183.396 163.714 104.686 1.00 54.76  ? 374  GLN C CB  1 
ATOM   8578  C CG  . GLN B 2 356 ? 182.292 163.120 105.540 1.00 54.76  ? 374  GLN C CG  1 
ATOM   8579  C CD  . GLN B 2 356 ? 180.952 163.719 105.222 1.00 54.76  ? 374  GLN C CD  1 
ATOM   8580  O OE1 . GLN B 2 356 ? 180.778 164.330 104.167 1.00 54.76  ? 374  GLN C OE1 1 
ATOM   8581  N NE2 . GLN B 2 356 ? 179.984 163.526 106.099 1.00 54.76  ? 374  GLN C NE2 1 
ATOM   8582  N N   . GLU B 2 357 ? 185.857 164.207 106.512 1.00 40.29  ? 375  GLU C N   1 
ATOM   8583  C CA  . GLU B 2 357 ? 186.253 164.487 107.866 1.00 40.29  ? 375  GLU C CA  1 
ATOM   8584  C C   . GLU B 2 357 ? 185.037 164.971 108.621 1.00 40.29  ? 375  GLU C C   1 
ATOM   8585  O O   . GLU B 2 357 ? 184.178 165.653 108.057 1.00 40.29  ? 375  GLU C O   1 
ATOM   8586  C CB  . GLU B 2 357 ? 187.344 165.555 107.906 1.00 53.10  ? 375  GLU C CB  1 
ATOM   8587  C CG  . GLU B 2 357 ? 188.667 165.165 107.266 1.00 53.10  ? 375  GLU C CG  1 
ATOM   8588  C CD  . GLU B 2 357 ? 189.683 166.270 107.394 1.00 53.10  ? 375  GLU C CD  1 
ATOM   8589  O OE1 . GLU B 2 357 ? 189.323 167.299 107.928 1.00 53.10  ? 375  GLU C OE1 1 
ATOM   8590  O OE2 . GLU B 2 357 ? 190.800 166.096 106.969 1.00 53.10  ? 375  GLU C OE2 1 
ATOM   8591  N N   . SER B 2 358 ? 185.033 164.745 109.932 1.00 40.29  ? 376  SER C N   1 
ATOM   8592  C CA  . SER B 2 358 ? 183.969 165.175 110.843 1.00 40.29  ? 376  SER C CA  1 
ATOM   8593  C C   . SER B 2 358 ? 183.880 166.676 110.912 1.00 40.29  ? 376  SER C C   1 
ATOM   8594  O O   . SER B 2 358 ? 182.843 167.239 111.246 1.00 40.29  ? 376  SER C O   1 
ATOM   8595  C CB  . SER B 2 358 ? 184.280 164.691 112.226 1.00 53.66  ? 376  SER C CB  1 
ATOM   8596  O OG  . SER B 2 358 ? 185.416 165.353 112.720 1.00 53.66  ? 376  SER C OG  1 
ATOM   8597  N N   . LYS B 2 359 ? 184.949 167.304 110.470 1.00 40.29  ? 377  LYS C N   1 
ATOM   8598  C CA  . LYS B 2 359 ? 185.198 168.720 110.436 1.00 40.29  ? 377  LYS C CA  1 
ATOM   8599  C C   . LYS B 2 359 ? 184.120 169.403 109.603 1.00 40.29  ? 377  LYS C C   1 
ATOM   8600  O O   . LYS B 2 359 ? 183.856 170.600 109.758 1.00 40.29  ? 377  LYS C O   1 
ATOM   8601  C CB  . LYS B 2 359 ? 186.561 168.971 109.802 1.00 57.63  ? 377  LYS C CB  1 
ATOM   8602  C CG  . LYS B 2 359 ? 187.152 170.333 110.024 1.00 57.63  ? 377  LYS C CG  1 
ATOM   8603  C CD  . LYS B 2 359 ? 187.801 170.463 111.434 1.00 57.63  ? 377  LYS C CD  1 
ATOM   8604  C CE  . LYS B 2 359 ? 188.354 171.835 111.577 1.00 57.63  ? 377  LYS C CE  1 
ATOM   8605  N NZ  . LYS B 2 359 ? 189.203 172.079 112.801 1.00 57.63  ? 377  LYS C NZ  1 
ATOM   8606  N N   . ILE B 2 360 ? 183.492 168.635 108.718 1.00 40.29  ? 378  ILE C N   1 
ATOM   8607  C CA  . ILE B 2 360 ? 182.447 169.110 107.842 1.00 40.29  ? 378  ILE C CA  1 
ATOM   8608  C C   . ILE B 2 360 ? 181.331 169.781 108.615 1.00 40.29  ? 378  ILE C C   1 
ATOM   8609  O O   . ILE B 2 360 ? 180.667 170.680 108.101 1.00 40.29  ? 378  ILE C O   1 
ATOM   8610  C CB  . ILE B 2 360 ? 181.850 167.923 107.047 1.00 57.27  ? 378  ILE C CB  1 
ATOM   8611  C CG1 . ILE B 2 360 ? 180.991 168.468 105.900 1.00 57.27  ? 378  ILE C CG1 1 
ATOM   8612  C CG2 . ILE B 2 360 ? 181.036 166.930 107.968 1.00 57.27  ? 378  ILE C CG2 1 
ATOM   8613  C CD1 . ILE B 2 360 ? 180.554 167.432 104.866 1.00 57.27  ? 378  ILE C CD1 1 
ATOM   8614  N N   . MET B 2 361 ? 181.121 169.364 109.852 1.00 40.29  ? 379  MET C N   1 
ATOM   8615  C CA  . MET B 2 361 ? 180.068 169.924 110.646 1.00 40.29  ? 379  MET C CA  1 
ATOM   8616  C C   . MET B 2 361 ? 180.360 171.347 111.033 1.00 40.29  ? 379  MET C C   1 
ATOM   8617  O O   . MET B 2 361 ? 179.438 172.115 111.285 1.00 40.29  ? 379  MET C O   1 
ATOM   8618  C CB  . MET B 2 361 ? 179.850 169.025 111.832 1.00 56.05  ? 379  MET C CB  1 
ATOM   8619  C CG  . MET B 2 361 ? 180.937 169.060 112.842 1.00 56.05  ? 379  MET C CG  1 
ATOM   8620  S SD  . MET B 2 361 ? 180.743 167.725 113.970 1.00 56.05  ? 379  MET C SD  1 
ATOM   8621  C CE  . MET B 2 361 ? 182.324 167.701 114.686 1.00 56.05  ? 379  MET C CE  1 
ATOM   8622  N N   . PHE B 2 362 ? 181.622 171.718 111.180 1.00 40.29  ? 380  PHE C N   1 
ATOM   8623  C CA  . PHE B 2 362 ? 181.943 173.094 111.491 1.00 40.29  ? 380  PHE C CA  1 
ATOM   8624  C C   . PHE B 2 362 ? 181.799 173.949 110.265 1.00 40.29  ? 380  PHE C C   1 
ATOM   8625  O O   . PHE B 2 362 ? 181.414 175.103 110.371 1.00 40.29  ? 380  PHE C O   1 
ATOM   8626  C CB  . PHE B 2 362 ? 183.361 173.190 111.990 1.00 54.49  ? 380  PHE C CB  1 
ATOM   8627  C CG  . PHE B 2 362 ? 183.626 172.213 113.084 1.00 54.49  ? 380  PHE C CG  1 
ATOM   8628  C CD1 . PHE B 2 362 ? 182.896 172.265 114.278 1.00 54.49  ? 380  PHE C CD1 1 
ATOM   8629  C CD2 . PHE B 2 362 ? 184.605 171.242 112.884 1.00 54.49  ? 380  PHE C CD2 1 
ATOM   8630  C CE1 . PHE B 2 362 ? 183.224 171.392 115.320 1.00 54.49  ? 380  PHE C CE1 1 
ATOM   8631  C CE2 . PHE B 2 362 ? 184.919 170.353 113.917 1.00 54.49  ? 380  PHE C CE2 1 
ATOM   8632  C CZ  . PHE B 2 362 ? 184.253 170.462 115.141 1.00 54.49  ? 380  PHE C CZ  1 
ATOM   8633  N N   . VAL B 2 363 ? 182.047 173.374 109.089 1.00 40.29  ? 381  VAL C N   1 
ATOM   8634  C CA  . VAL B 2 363 ? 181.921 174.143 107.875 1.00 40.29  ? 381  VAL C CA  1 
ATOM   8635  C C   . VAL B 2 363 ? 180.468 174.571 107.788 1.00 40.29  ? 381  VAL C C   1 
ATOM   8636  O O   . VAL B 2 363 ? 180.147 175.713 107.426 1.00 40.29  ? 381  VAL C O   1 
ATOM   8637  C CB  . VAL B 2 363 ? 182.288 173.298 106.648 1.00 56.74  ? 381  VAL C CB  1 
ATOM   8638  C CG1 . VAL B 2 363 ? 181.977 174.056 105.383 1.00 56.74  ? 381  VAL C CG1 1 
ATOM   8639  C CG2 . VAL B 2 363 ? 183.756 172.919 106.700 1.00 56.74  ? 381  VAL C CG2 1 
ATOM   8640  N N   . VAL B 2 364 ? 179.603 173.616 108.086 1.00 40.29  ? 382  VAL C N   1 
ATOM   8641  C CA  . VAL B 2 364 ? 178.190 173.836 108.053 1.00 40.29  ? 382  VAL C CA  1 
ATOM   8642  C C   . VAL B 2 364 ? 177.733 174.715 109.202 1.00 40.29  ? 382  VAL C C   1 
ATOM   8643  O O   . VAL B 2 364 ? 176.967 175.653 108.992 1.00 40.29  ? 382  VAL C O   1 
ATOM   8644  C CB  . VAL B 2 364 ? 177.476 172.501 108.014 1.00 56.74  ? 382  VAL C CB  1 
ATOM   8645  C CG1 . VAL B 2 364 ? 175.975 172.684 108.115 1.00 56.74  ? 382  VAL C CG1 1 
ATOM   8646  C CG2 . VAL B 2 364 ? 177.869 171.846 106.706 1.00 56.74  ? 382  VAL C CG2 1 
ATOM   8647  N N   . ASN B 2 365 ? 178.209 174.475 110.413 1.00 40.29  ? 383  ASN C N   1 
ATOM   8648  C CA  . ASN B 2 365 ? 177.760 175.330 111.479 1.00 40.29  ? 383  ASN C CA  1 
ATOM   8649  C C   . ASN B 2 365 ? 178.188 176.759 111.226 1.00 40.29  ? 383  ASN C C   1 
ATOM   8650  O O   . ASN B 2 365 ? 177.448 177.674 111.566 1.00 40.29  ? 383  ASN C O   1 
ATOM   8651  C CB  . ASN B 2 365 ? 178.297 174.875 112.814 1.00 53.59  ? 383  ASN C CB  1 
ATOM   8652  C CG  . ASN B 2 365 ? 177.649 173.651 113.313 1.00 53.59  ? 383  ASN C CG  1 
ATOM   8653  O OD1 . ASN B 2 365 ? 176.540 173.307 112.903 1.00 53.59  ? 383  ASN C OD1 1 
ATOM   8654  N ND2 . ASN B 2 365 ? 178.319 172.964 114.204 1.00 53.59  ? 383  ASN C ND2 1 
ATOM   8655  N N   . ALA B 2 366 ? 179.363 176.984 110.626 1.00 40.29  ? 384  ALA C N   1 
ATOM   8656  C CA  . ALA B 2 366 ? 179.794 178.346 110.382 1.00 40.29  ? 384  ALA C CA  1 
ATOM   8657  C C   . ALA B 2 366 ? 178.848 179.067 109.428 1.00 40.29  ? 384  ALA C C   1 
ATOM   8658  O O   . ALA B 2 366 ? 178.469 180.220 109.674 1.00 40.29  ? 384  ALA C O   1 
ATOM   8659  C CB  . ALA B 2 366 ? 181.196 178.352 109.818 1.00 54.43  ? 384  ALA C CB  1 
ATOM   8660  N N   . VAL B 2 367 ? 178.367 178.378 108.385 1.00 40.29  ? 385  VAL C N   1 
ATOM   8661  C CA  . VAL B 2 367 ? 177.465 179.072 107.474 1.00 40.29  ? 385  VAL C CA  1 
ATOM   8662  C C   . VAL B 2 367 ? 176.097 179.269 108.090 1.00 40.29  ? 385  VAL C C   1 
ATOM   8663  O O   . VAL B 2 367 ? 175.467 180.306 107.859 1.00 40.29  ? 385  VAL C O   1 
ATOM   8664  C CB  . VAL B 2 367 ? 177.330 178.378 106.093 1.00 56.74  ? 385  VAL C CB  1 
ATOM   8665  C CG1 . VAL B 2 367 ? 178.670 178.272 105.373 1.00 56.74  ? 385  VAL C CG1 1 
ATOM   8666  C CG2 . VAL B 2 367 ? 176.815 177.054 106.222 1.00 56.74  ? 385  VAL C CG2 1 
ATOM   8667  N N   . TYR B 2 368 ? 175.626 178.309 108.873 1.00 40.29  ? 386  TYR C N   1 
ATOM   8668  C CA  . TYR B 2 368 ? 174.333 178.489 109.470 1.00 40.29  ? 386  TYR C CA  1 
ATOM   8669  C C   . TYR B 2 368 ? 174.378 179.498 110.574 1.00 40.29  ? 386  TYR C C   1 
ATOM   8670  O O   . TYR B 2 368 ? 173.432 180.262 110.732 1.00 40.29  ? 386  TYR C O   1 
ATOM   8671  C CB  . TYR B 2 368 ? 173.775 177.167 109.946 1.00 54.08  ? 386  TYR C CB  1 
ATOM   8672  C CG  . TYR B 2 368 ? 173.123 176.415 108.854 1.00 54.08  ? 386  TYR C CG  1 
ATOM   8673  C CD1 . TYR B 2 368 ? 171.794 176.638 108.625 1.00 54.08  ? 386  TYR C CD1 1 
ATOM   8674  C CD2 . TYR B 2 368 ? 173.800 175.510 108.092 1.00 54.08  ? 386  TYR C CD2 1 
ATOM   8675  C CE1 . TYR B 2 368 ? 171.139 175.961 107.631 1.00 54.08  ? 386  TYR C CE1 1 
ATOM   8676  C CE2 . TYR B 2 368 ? 173.154 174.837 107.097 1.00 54.08  ? 386  TYR C CE2 1 
ATOM   8677  C CZ  . TYR B 2 368 ? 171.828 175.061 106.868 1.00 54.08  ? 386  TYR C CZ  1 
ATOM   8678  O OH  . TYR B 2 368 ? 171.202 174.385 105.868 1.00 54.08  ? 386  TYR C OH  1 
ATOM   8679  N N   . ALA B 2 369 ? 175.455 179.524 111.347 1.00 40.29  ? 387  ALA C N   1 
ATOM   8680  C CA  . ALA B 2 369 ? 175.568 180.468 112.429 1.00 40.29  ? 387  ALA C CA  1 
ATOM   8681  C C   . ALA B 2 369 ? 175.626 181.864 111.871 1.00 40.29  ? 387  ALA C C   1 
ATOM   8682  O O   . ALA B 2 369 ? 175.013 182.778 112.428 1.00 40.29  ? 387  ALA C O   1 
ATOM   8683  C CB  . ALA B 2 369 ? 176.786 180.161 113.269 1.00 54.43  ? 387  ALA C CB  1 
ATOM   8684  N N   . MET B 2 370 ? 176.326 182.048 110.747 1.00 40.29  ? 388  MET C N   1 
ATOM   8685  C CA  . MET B 2 370 ? 176.381 183.373 110.183 1.00 40.29  ? 388  MET C CA  1 
ATOM   8686  C C   . MET B 2 370 ? 175.021 183.729 109.633 1.00 40.29  ? 388  MET C C   1 
ATOM   8687  O O   . MET B 2 370 ? 174.546 184.842 109.848 1.00 40.29  ? 388  MET C O   1 
ATOM   8688  C CB  . MET B 2 370 ? 177.449 183.449 109.102 1.00 56.05  ? 388  MET C CB  1 
ATOM   8689  C CG  . MET B 2 370 ? 177.683 184.852 108.489 1.00 56.05  ? 388  MET C CG  1 
ATOM   8690  S SD  . MET B 2 370 ? 178.235 186.110 109.679 1.00 56.05  ? 388  MET C SD  1 
ATOM   8691  C CE  . MET B 2 370 ? 179.960 185.680 109.961 1.00 56.05  ? 388  MET C CE  1 
ATOM   8692  N N   . ALA B 2 371 ? 174.365 182.784 108.957 1.00 40.29  ? 389  ALA C N   1 
ATOM   8693  C CA  . ALA B 2 371 ? 173.066 183.063 108.394 1.00 40.29  ? 389  ALA C CA  1 
ATOM   8694  C C   . ALA B 2 371 ? 172.070 183.398 109.474 1.00 40.29  ? 389  ALA C C   1 
ATOM   8695  O O   . ALA B 2 371 ? 171.226 184.277 109.307 1.00 40.29  ? 389  ALA C O   1 
ATOM   8696  C CB  . ALA B 2 371 ? 172.595 181.875 107.612 1.00 54.43  ? 389  ALA C CB  1 
ATOM   8697  N N   . HIS B 2 372 ? 172.169 182.717 110.598 1.00 40.29  ? 390  HIS C N   1 
ATOM   8698  C CA  . HIS B 2 372 ? 171.273 182.957 111.691 1.00 40.29  ? 390  HIS C CA  1 
ATOM   8699  C C   . HIS B 2 372 ? 171.551 184.317 112.271 1.00 40.29  ? 390  HIS C C   1 
ATOM   8700  O O   . HIS B 2 372 ? 170.627 185.080 112.542 1.00 40.29  ? 390  HIS C O   1 
ATOM   8701  C CB  . HIS B 2 372 ? 171.368 181.876 112.723 1.00 53.51  ? 390  HIS C CB  1 
ATOM   8702  C CG  . HIS B 2 372 ? 170.355 182.004 113.742 1.00 53.51  ? 390  HIS C CG  1 
ATOM   8703  N ND1 . HIS B 2 372 ? 169.021 181.759 113.484 1.00 53.51  ? 390  HIS C ND1 1 
ATOM   8704  C CD2 . HIS B 2 372 ? 170.433 182.354 115.033 1.00 53.51  ? 390  HIS C CD2 1 
ATOM   8705  C CE1 . HIS B 2 372 ? 168.323 181.961 114.575 1.00 53.51  ? 390  HIS C CE1 1 
ATOM   8706  N NE2 . HIS B 2 372 ? 169.151 182.338 115.533 1.00 53.51  ? 390  HIS C NE2 1 
ATOM   8707  N N   . ALA B 2 373 ? 172.817 184.668 112.434 1.00 40.29  ? 391  ALA C N   1 
ATOM   8708  C CA  . ALA B 2 373 ? 173.109 185.979 112.950 1.00 40.29  ? 391  ALA C CA  1 
ATOM   8709  C C   . ALA B 2 373 ? 172.519 187.042 112.034 1.00 40.29  ? 391  ALA C C   1 
ATOM   8710  O O   . ALA B 2 373 ? 171.976 188.045 112.503 1.00 40.29  ? 391  ALA C O   1 
ATOM   8711  C CB  . ALA B 2 373 ? 174.593 186.160 113.048 1.00 54.43  ? 391  ALA C CB  1 
ATOM   8712  N N   . LEU B 2 374 ? 172.582 186.804 110.721 1.00 40.29  ? 392  LEU C N   1 
ATOM   8713  C CA  . LEU B 2 374 ? 172.018 187.739 109.775 1.00 40.29  ? 392  LEU C CA  1 
ATOM   8714  C C   . LEU B 2 374 ? 170.516 187.761 109.913 1.00 40.29  ? 392  LEU C C   1 
ATOM   8715  O O   . LEU B 2 374 ? 169.902 188.822 109.831 1.00 40.29  ? 392  LEU C O   1 
ATOM   8716  C CB  . LEU B 2 374 ? 172.342 187.337 108.343 1.00 57.27  ? 392  LEU C CB  1 
ATOM   8717  C CG  . LEU B 2 374 ? 173.774 187.407 107.885 1.00 57.27  ? 392  LEU C CG  1 
ATOM   8718  C CD1 . LEU B 2 374 ? 173.821 186.785 106.513 1.00 57.27  ? 392  LEU C CD1 1 
ATOM   8719  C CD2 . LEU B 2 374 ? 174.270 188.836 107.879 1.00 57.27  ? 392  LEU C CD2 1 
ATOM   8720  N N   . HIS B 2 375 ? 169.929 186.603 110.159 1.00 40.29  ? 393  HIS C N   1 
ATOM   8721  C CA  . HIS B 2 375 ? 168.501 186.452 110.312 1.00 40.29  ? 393  HIS C CA  1 
ATOM   8722  C C   . HIS B 2 375 ? 168.022 187.276 111.478 1.00 40.29  ? 393  HIS C C   1 
ATOM   8723  O O   . HIS B 2 375 ? 167.048 188.027 111.357 1.00 40.29  ? 393  HIS C O   1 
ATOM   8724  C CB  . HIS B 2 375 ? 168.168 184.983 110.534 1.00 53.51  ? 393  HIS C CB  1 
ATOM   8725  C CG  . HIS B 2 375 ? 166.765 184.663 110.597 1.00 53.51  ? 393  HIS C CG  1 
ATOM   8726  N ND1 . HIS B 2 375 ? 165.974 184.538 109.469 1.00 53.51  ? 393  HIS C ND1 1 
ATOM   8727  C CD2 . HIS B 2 375 ? 165.965 184.439 111.654 1.00 53.51  ? 393  HIS C CD2 1 
ATOM   8728  C CE1 . HIS B 2 375 ? 164.739 184.255 109.847 1.00 53.51  ? 393  HIS C CE1 1 
ATOM   8729  N NE2 . HIS B 2 375 ? 164.712 184.187 111.165 1.00 53.51  ? 393  HIS C NE2 1 
ATOM   8730  N N   . ASN B 2 376 ? 168.715 187.167 112.602 1.00 40.29  ? 394  ASN C N   1 
ATOM   8731  C CA  . ASN B 2 376 ? 168.320 187.900 113.777 1.00 40.29  ? 394  ASN C CA  1 
ATOM   8732  C C   . ASN B 2 376 ? 168.601 189.370 113.601 1.00 40.29  ? 394  ASN C C   1 
ATOM   8733  O O   . ASN B 2 376 ? 167.839 190.204 114.099 1.00 40.29  ? 394  ASN C O   1 
ATOM   8734  C CB  . ASN B 2 376 ? 168.991 187.323 114.966 1.00 53.59  ? 394  ASN C CB  1 
ATOM   8735  C CG  . ASN B 2 376 ? 168.431 186.022 115.253 1.00 53.59  ? 394  ASN C CG  1 
ATOM   8736  O OD1 . ASN B 2 376 ? 167.271 185.738 114.899 1.00 53.59  ? 394  ASN C OD1 1 
ATOM   8737  N ND2 . ASN B 2 376 ? 169.216 185.194 115.859 1.00 53.59  ? 394  ASN C ND2 1 
ATOM   8738  N N   . MET B 2 377 ? 169.654 189.692 112.854 1.00 40.29  ? 395  MET C N   1 
ATOM   8739  C CA  . MET B 2 377 ? 169.936 191.060 112.541 1.00 40.29  ? 395  MET C CA  1 
ATOM   8740  C C   . MET B 2 377 ? 168.805 191.652 111.751 1.00 40.29  ? 395  MET C C   1 
ATOM   8741  O O   . MET B 2 377 ? 168.391 192.775 112.025 1.00 40.29  ? 395  MET C O   1 
ATOM   8742  C CB  . MET B 2 377 ? 171.215 191.172 111.761 1.00 56.05  ? 395  MET C CB  1 
ATOM   8743  C CG  . MET B 2 377 ? 171.460 192.506 111.285 1.00 56.05  ? 395  MET C CG  1 
ATOM   8744  S SD  . MET B 2 377 ? 171.690 193.696 112.467 1.00 56.05  ? 395  MET C SD  1 
ATOM   8745  C CE  . MET B 2 377 ? 173.334 193.695 112.525 1.00 56.05  ? 395  MET C CE  1 
ATOM   8746  N N   . HIS B 2 378 ? 168.268 190.892 110.801 1.00 40.29  ? 396  HIS C N   1 
ATOM   8747  C CA  . HIS B 2 378 ? 167.153 191.379 110.025 1.00 40.29  ? 396  HIS C CA  1 
ATOM   8748  C C   . HIS B 2 378 ? 165.914 191.448 110.884 1.00 40.29  ? 396  HIS C C   1 
ATOM   8749  O O   . HIS B 2 378 ? 165.155 192.402 110.804 1.00 40.29  ? 396  HIS C O   1 
ATOM   8750  C CB  . HIS B 2 378 ? 166.887 190.507 108.801 1.00 53.51  ? 396  HIS C CB  1 
ATOM   8751  C CG  . HIS B 2 378 ? 167.853 190.726 107.692 1.00 53.51  ? 396  HIS C CG  1 
ATOM   8752  N ND1 . HIS B 2 378 ? 169.107 190.168 107.674 1.00 53.51  ? 396  HIS C ND1 1 
ATOM   8753  C CD2 . HIS B 2 378 ? 167.743 191.450 106.558 1.00 53.51  ? 396  HIS C CD2 1 
ATOM   8754  C CE1 . HIS B 2 378 ? 169.732 190.536 106.577 1.00 53.51  ? 396  HIS C CE1 1 
ATOM   8755  N NE2 . HIS B 2 378 ? 168.923 191.315 105.880 1.00 53.51  ? 396  HIS C NE2 1 
ATOM   8756  N N   . ARG B 2 379 ? 165.707 190.516 111.787 1.00 40.29  ? 397  ARG C N   1 
ATOM   8757  C CA  . ARG B 2 379 ? 164.516 190.676 112.590 1.00 40.29  ? 397  ARG C CA  1 
ATOM   8758  C C   . ARG B 2 379 ? 164.608 191.985 113.397 1.00 40.29  ? 397  ARG C C   1 
ATOM   8759  O O   . ARG B 2 379 ? 163.606 192.675 113.581 1.00 40.29  ? 397  ARG C O   1 
ATOM   8760  C CB  . ARG B 2 379 ? 164.304 189.475 113.504 1.00 55.54  ? 397  ARG C CB  1 
ATOM   8761  C CG  . ARG B 2 379 ? 163.898 188.201 112.744 1.00 55.54  ? 397  ARG C CG  1 
ATOM   8762  C CD  . ARG B 2 379 ? 163.370 187.103 113.608 1.00 55.54  ? 397  ARG C CD  1 
ATOM   8763  N NE  . ARG B 2 379 ? 164.376 186.358 114.400 1.00 55.54  ? 397  ARG C NE  1 
ATOM   8764  C CZ  . ARG B 2 379 ? 164.050 185.459 115.364 1.00 55.54  ? 397  ARG C CZ  1 
ATOM   8765  N NH1 . ARG B 2 379 ? 165.003 184.813 116.003 1.00 55.54  ? 397  ARG C NH1 1 
ATOM   8766  N NH2 . ARG B 2 379 ? 162.787 185.222 115.664 1.00 55.54  ? 397  ARG C NH2 1 
ATOM   8767  N N   . ALA B 2 380 ? 165.810 192.328 113.877 1.00 40.29  ? 398  ALA C N   1 
ATOM   8768  C CA  . ALA B 2 380 ? 166.029 193.568 114.620 1.00 40.29  ? 398  ALA C CA  1 
ATOM   8769  C C   . ALA B 2 380 ? 166.015 194.855 113.760 1.00 40.29  ? 398  ALA C C   1 
ATOM   8770  O O   . ALA B 2 380 ? 165.479 195.881 114.189 1.00 40.29  ? 398  ALA C O   1 
ATOM   8771  C CB  . ALA B 2 380 ? 167.367 193.480 115.325 1.00 54.43  ? 398  ALA C CB  1 
ATOM   8772  N N   . LEU B 2 381 ? 166.602 194.811 112.557 1.00 40.29  ? 399  LEU C N   1 
ATOM   8773  C CA  . LEU B 2 381 ? 166.709 195.989 111.665 1.00 40.29  ? 399  LEU C CA  1 
ATOM   8774  C C   . LEU B 2 381 ? 165.680 196.107 110.523 1.00 40.29  ? 399  LEU C C   1 
ATOM   8775  O O   . LEU B 2 381 ? 165.473 197.209 110.010 1.00 40.29  ? 399  LEU C O   1 
ATOM   8776  C CB  . LEU B 2 381 ? 168.123 196.069 111.045 1.00 57.27  ? 399  LEU C CB  1 
ATOM   8777  C CG  . LEU B 2 381 ? 169.223 196.857 111.835 1.00 57.27  ? 399  LEU C CG  1 
ATOM   8778  C CD1 . LEU B 2 381 ? 169.365 196.279 113.255 1.00 57.27  ? 399  LEU C CD1 1 
ATOM   8779  C CD2 . LEU B 2 381 ? 170.556 196.780 111.027 1.00 57.27  ? 399  LEU C CD2 1 
ATOM   8780  N N   . CYS B 2 382 ? 165.039 194.973 110.150 1.00 43.13  ? 400  CYS C N   1 
ATOM   8781  C CA  . CYS B 2 382 ? 164.071 194.840 109.064 1.00 43.13  ? 400  CYS C CA  1 
ATOM   8782  C C   . CYS B 2 382 ? 162.892 193.991 109.611 1.00 43.13  ? 400  CYS C C   1 
ATOM   8783  O O   . CYS B 2 382 ? 162.410 193.062 108.970 1.00 43.13  ? 400  CYS C O   1 
ATOM   8784  C CB  . CYS B 2 382 ? 164.814 194.114 107.893 1.00 55.89  ? 400  CYS C CB  1 
ATOM   8785  S SG  . CYS B 2 382 ? 163.957 193.991 106.322 1.00 55.89  ? 400  CYS C SG  1 
ATOM   8786  N N   . PRO B 2 383 ? 162.273 194.438 110.744 1.00 47.58  ? 401  PRO C N   1 
ATOM   8787  C CA  . PRO B 2 383 ? 161.281 193.709 111.532 1.00 47.58  ? 401  PRO C CA  1 
ATOM   8788  C C   . PRO B 2 383 ? 159.936 193.480 110.890 1.00 47.58  ? 401  PRO C C   1 
ATOM   8789  O O   . PRO B 2 383 ? 159.159 192.643 111.344 1.00 47.58  ? 401  PRO C O   1 
ATOM   8790  C CB  . PRO B 2 383 ? 161.063 194.641 112.732 1.00 81.30  ? 401  PRO C CB  1 
ATOM   8791  C CG  . PRO B 2 383 ? 161.411 196.024 112.218 1.00 81.30  ? 401  PRO C CG  1 
ATOM   8792  C CD  . PRO B 2 383 ? 162.548 195.794 111.291 1.00 81.30  ? 401  PRO C CD  1 
ATOM   8793  N N   . ASN B 2 384 ? 159.626 194.259 109.876 1.00 52.01  ? 402  ASN C N   1 
ATOM   8794  C CA  . ASN B 2 384 ? 158.328 194.187 109.259 1.00 52.01  ? 402  ASN C CA  1 
ATOM   8795  C C   . ASN B 2 384 ? 158.387 193.908 107.780 1.00 52.01  ? 402  ASN C C   1 
ATOM   8796  O O   . ASN B 2 384 ? 157.397 194.101 107.072 1.00 52.01  ? 402  ASN C O   1 
ATOM   8797  C CB  . ASN B 2 384 ? 157.645 195.497 109.524 1.00 69.18  ? 402  ASN C CB  1 
ATOM   8798  C CG  . ASN B 2 384 ? 158.454 196.619 108.921 1.00 69.18  ? 402  ASN C CG  1 
ATOM   8799  O OD1 . ASN B 2 384 ? 159.510 196.376 108.283 1.00 69.18  ? 402  ASN C OD1 1 
ATOM   8800  N ND2 . ASN B 2 384 ? 158.005 197.833 109.115 1.00 69.18  ? 402  ASN C ND2 1 
ATOM   8801  N N   . THR B 2 385 ? 159.535 193.469 107.302 1.00 52.20  ? 403  THR C N   1 
ATOM   8802  C CA  . THR B 2 385 ? 159.684 193.249 105.882 1.00 52.20  ? 403  THR C CA  1 
ATOM   8803  C C   . THR B 2 385 ? 160.225 191.848 105.608 1.00 52.20  ? 403  THR C C   1 
ATOM   8804  O O   . THR B 2 385 ? 161.031 191.307 106.362 1.00 52.20  ? 403  THR C O   1 
ATOM   8805  C CB  . THR B 2 385 ? 160.492 194.417 105.295 1.00 71.46  ? 403  THR C CB  1 
ATOM   8806  O OG1 . THR B 2 385 ? 159.767 195.641 105.517 1.00 71.46  ? 403  THR C OG1 1 
ATOM   8807  C CG2 . THR B 2 385 ? 160.769 194.280 103.824 1.00 71.46  ? 403  THR C CG2 1 
ATOM   8808  N N   . THR B 2 386 ? 159.736 191.248 104.526 1.00 48.24  ? 404  THR C N   1 
ATOM   8809  C CA  . THR B 2 386 ? 160.043 189.879 104.115 1.00 48.24  ? 404  THR C CA  1 
ATOM   8810  C C   . THR B 2 386 ? 161.150 189.763 103.075 1.00 48.24  ? 404  THR C C   1 
ATOM   8811  O O   . THR B 2 386 ? 161.398 188.683 102.529 1.00 48.24  ? 404  THR C O   1 
ATOM   8812  C CB  . THR B 2 386 ? 158.768 189.232 103.569 1.00 66.04  ? 404  THR C CB  1 
ATOM   8813  O OG1 . THR B 2 386 ? 158.288 190.018 102.466 1.00 66.04  ? 404  THR C OG1 1 
ATOM   8814  C CG2 . THR B 2 386 ? 157.706 189.190 104.658 1.00 66.04  ? 404  THR C CG2 1 
ATOM   8815  N N   . ARG B 2 387 ? 161.788 190.883 102.796 1.00 49.56  ? 405  ARG C N   1 
ATOM   8816  C CA  . ARG B 2 387 ? 162.890 191.012 101.857 1.00 49.56  ? 405  ARG C CA  1 
ATOM   8817  C C   . ARG B 2 387 ? 163.972 191.857 102.501 1.00 49.56  ? 405  ARG C C   1 
ATOM   8818  O O   . ARG B 2 387 ? 163.676 192.730 103.301 1.00 49.56  ? 405  ARG C O   1 
ATOM   8819  C CB  . ARG B 2 387 ? 162.437 191.661 100.559 1.00 69.60  ? 405  ARG C CB  1 
ATOM   8820  C CG  . ARG B 2 387 ? 161.394 190.867 99.769  1.00 69.60  ? 405  ARG C CG  1 
ATOM   8821  C CD  . ARG B 2 387 ? 161.966 189.623 99.180  1.00 69.60  ? 405  ARG C CD  1 
ATOM   8822  N NE  . ARG B 2 387 ? 161.002 188.919 98.365  1.00 69.60  ? 405  ARG C NE  1 
ATOM   8823  C CZ  . ARG B 2 387 ? 160.107 188.008 98.819  1.00 69.60  ? 405  ARG C CZ  1 
ATOM   8824  N NH1 . ARG B 2 387 ? 159.286 187.429 97.953  1.00 69.60  ? 405  ARG C NH1 1 
ATOM   8825  N NH2 . ARG B 2 387 ? 160.032 187.684 100.102 1.00 69.60  ? 405  ARG C NH2 1 
ATOM   8826  N N   . LEU B 2 388 ? 165.217 191.669 102.098 1.00 49.73  ? 406  LEU C N   1 
ATOM   8827  C CA  . LEU B 2 388 ? 166.287 192.487 102.673 1.00 49.73  ? 406  LEU C CA  1 
ATOM   8828  C C   . LEU B 2 388 ? 165.986 193.993 102.538 1.00 49.73  ? 406  LEU C C   1 
ATOM   8829  O O   . LEU B 2 388 ? 165.592 194.465 101.466 1.00 49.73  ? 406  LEU C O   1 
ATOM   8830  C CB  . LEU B 2 388 ? 167.632 192.173 101.977 1.00 70.68  ? 406  LEU C CB  1 
ATOM   8831  C CG  . LEU B 2 388 ? 168.920 192.873 102.572 1.00 70.68  ? 406  LEU C CG  1 
ATOM   8832  C CD1 . LEU B 2 388 ? 170.095 191.921 102.493 1.00 70.68  ? 406  LEU C CD1 1 
ATOM   8833  C CD2 . LEU B 2 388 ? 169.274 194.144 101.757 1.00 70.68  ? 406  LEU C CD2 1 
ATOM   8834  N N   . CYS B 2 389 ? 166.180 194.722 103.666 1.00 56.59  ? 407  CYS C N   1 
ATOM   8835  C CA  . CYS B 2 389 ? 165.980 196.153 103.863 1.00 56.59  ? 407  CYS C CA  1 
ATOM   8836  C C   . CYS B 2 389 ? 167.290 196.897 103.681 1.00 56.59  ? 407  CYS C C   1 
ATOM   8837  O O   . CYS B 2 389 ? 168.375 196.391 103.993 1.00 56.59  ? 407  CYS C O   1 
ATOM   8838  C CB  . CYS B 2 389 ? 165.430 196.498 105.281 1.00 73.33  ? 407  CYS C CB  1 
ATOM   8839  S SG  . CYS B 2 389 ? 163.762 195.906 105.672 1.00 73.33  ? 407  CYS C SG  1 
ATOM   8840  N N   . ASP B 2 390 ? 167.163 198.186 103.390 1.00 59.00  ? 408  ASP C N   1 
ATOM   8841  C CA  . ASP B 2 390 ? 168.301 199.072 103.192 1.00 59.00  ? 408  ASP C CA  1 
ATOM   8842  C C   . ASP B 2 390 ? 169.212 199.184 104.415 1.00 59.00  ? 408  ASP C C   1 
ATOM   8843  O O   . ASP B 2 390 ? 170.394 199.518 104.314 1.00 59.00  ? 408  ASP C O   1 
ATOM   8844  C CB  . ASP B 2 390 ? 167.814 200.443 102.777 1.00 75.13  ? 408  ASP C CB  1 
ATOM   8845  C CG  . ASP B 2 390 ? 167.258 200.435 101.356 1.00 75.13  ? 408  ASP C CG  1 
ATOM   8846  O OD1 . ASP B 2 390 ? 167.514 199.488 100.607 1.00 75.13  ? 408  ASP C OD1 1 
ATOM   8847  O OD2 . ASP B 2 390 ? 166.567 201.359 101.030 1.00 75.13  ? 408  ASP C OD2 1 
ATOM   8848  N N   . ALA B 2 391 ? 168.667 198.853 105.571 1.00 57.67  ? 409  ALA C N   1 
ATOM   8849  C CA  . ALA B 2 391 ? 169.357 198.879 106.848 1.00 57.67  ? 409  ALA C CA  1 
ATOM   8850  C C   . ALA B 2 391 ? 170.591 197.969 106.831 1.00 57.67  ? 409  ALA C C   1 
ATOM   8851  O O   . ALA B 2 391 ? 171.535 198.168 107.607 1.00 57.67  ? 409  ALA C O   1 
ATOM   8852  C CB  . ALA B 2 391 ? 168.401 198.437 107.939 1.00 77.91  ? 409  ALA C CB  1 
ATOM   8853  N N   . MET B 2 392 ? 170.548 196.935 105.985 1.00 54.31  ? 410  MET C N   1 
ATOM   8854  C CA  . MET B 2 392 ? 171.628 195.978 105.859 1.00 54.31  ? 410  MET C CA  1 
ATOM   8855  C C   . MET B 2 392 ? 172.504 196.170 104.640 1.00 54.31  ? 410  MET C C   1 
ATOM   8856  O O   . MET B 2 392 ? 173.308 195.295 104.314 1.00 54.31  ? 410  MET C O   1 
ATOM   8857  C CB  . MET B 2 392 ? 171.085 194.566 105.930 1.00 75.56  ? 410  MET C CB  1 
ATOM   8858  C CG  . MET B 2 392 ? 170.600 194.218 107.299 1.00 75.56  ? 410  MET C CG  1 
ATOM   8859  S SD  . MET B 2 392 ? 171.930 194.313 108.496 1.00 75.56  ? 410  MET C SD  1 
ATOM   8860  C CE  . MET B 2 392 ? 173.012 192.926 108.083 1.00 75.56  ? 410  MET C CE  1 
ATOM   8861  N N   . ARG B 2 393 ? 172.364 197.302 103.959 1.00 54.63  ? 411  ARG C N   1 
ATOM   8862  C CA  . ARG B 2 393 ? 173.234 197.572 102.842 1.00 54.63  ? 411  ARG C CA  1 
ATOM   8863  C C   . ARG B 2 393 ? 174.640 197.948 103.344 1.00 54.63  ? 411  ARG C C   1 
ATOM   8864  O O   . ARG B 2 393 ? 175.615 197.562 102.702 1.00 54.63  ? 411  ARG C O   1 
ATOM   8865  C CB  . ARG B 2 393 ? 172.710 198.701 101.976 1.00 76.72  ? 411  ARG C CB  1 
ATOM   8866  C CG  . ARG B 2 393 ? 171.368 198.465 101.424 1.00 76.72  ? 411  ARG C CG  1 
ATOM   8867  C CD  . ARG B 2 393 ? 171.204 197.480 100.366 1.00 76.72  ? 411  ARG C CD  1 
ATOM   8868  N NE  . ARG B 2 393 ? 169.793 197.517 99.942  1.00 76.72  ? 411  ARG C NE  1 
ATOM   8869  C CZ  . ARG B 2 393 ? 169.157 196.661 99.140  1.00 76.72  ? 411  ARG C CZ  1 
ATOM   8870  N NH1 . ARG B 2 393 ? 167.884 196.907 98.918  1.00 76.72  ? 411  ARG C NH1 1 
ATOM   8871  N NH2 . ARG B 2 393 ? 169.765 195.619 98.594  1.00 76.72  ? 411  ARG C NH2 1 
ATOM   8872  N N   . PRO B 2 394 ? 174.808 198.761 104.426 1.00 48.86  ? 412  PRO C N   1 
ATOM   8873  C CA  . PRO B 2 394 ? 176.084 199.160 104.946 1.00 48.86  ? 412  PRO C CA  1 
ATOM   8874  C C   . PRO B 2 394 ? 176.657 198.019 105.735 1.00 48.86  ? 412  PRO C C   1 
ATOM   8875  O O   . PRO B 2 394 ? 175.946 197.077 106.086 1.00 48.86  ? 412  PRO C O   1 
ATOM   8876  C CB  . PRO B 2 394 ? 175.750 200.359 105.826 1.00 83.49  ? 412  PRO C CB  1 
ATOM   8877  C CG  . PRO B 2 394 ? 174.396 200.063 106.349 1.00 83.49  ? 412  PRO C CG  1 
ATOM   8878  C CD  . PRO B 2 394 ? 173.687 199.326 105.251 1.00 83.49  ? 412  PRO C CD  1 
ATOM   8879  N N   . VAL B 2 395 ? 177.920 198.119 106.051 1.00 40.29  ? 413  VAL C N   1 
ATOM   8880  C CA  . VAL B 2 395 ? 178.511 197.159 106.942 1.00 40.29  ? 413  VAL C CA  1 
ATOM   8881  C C   . VAL B 2 395 ? 178.125 197.559 108.365 1.00 40.29  ? 413  VAL C C   1 
ATOM   8882  O O   . VAL B 2 395 ? 178.289 198.715 108.748 1.00 40.29  ? 413  VAL C O   1 
ATOM   8883  C CB  . VAL B 2 395 ? 180.025 197.129 106.729 1.00 56.74  ? 413  VAL C CB  1 
ATOM   8884  C CG1 . VAL B 2 395 ? 180.634 196.223 107.689 1.00 56.74  ? 413  VAL C CG1 1 
ATOM   8885  C CG2 . VAL B 2 395 ? 180.331 196.678 105.298 1.00 56.74  ? 413  VAL C CG2 1 
ATOM   8886  N N   . ASN B 2 396 ? 177.599 196.609 109.135 1.00 40.29  ? 414  ASN C N   1 
ATOM   8887  C CA  . ASN B 2 396 ? 177.118 196.894 110.483 1.00 40.29  ? 414  ASN C CA  1 
ATOM   8888  C C   . ASN B 2 396 ? 178.016 196.606 111.714 1.00 40.29  ? 414  ASN C C   1 
ATOM   8889  O O   . ASN B 2 396 ? 177.551 196.803 112.845 1.00 40.29  ? 414  ASN C O   1 
ATOM   8890  C CB  . ASN B 2 396 ? 175.759 196.229 110.629 1.00 53.59  ? 414  ASN C CB  1 
ATOM   8891  C CG  . ASN B 2 396 ? 174.595 197.001 109.955 1.00 53.59  ? 414  ASN C CG  1 
ATOM   8892  O OD1 . ASN B 2 396 ? 174.048 197.929 110.573 1.00 53.59  ? 414  ASN C OD1 1 
ATOM   8893  N ND2 . ASN B 2 396 ? 174.226 196.663 108.756 1.00 53.59  ? 414  ASN C ND2 1 
ATOM   8894  N N   . GLY B 2 397 ? 179.272 196.175 111.556 1.00 40.29  ? 415  GLY C N   1 
ATOM   8895  C CA  . GLY B 2 397 ? 180.129 196.031 112.719 1.00 40.29  ? 415  GLY C CA  1 
ATOM   8896  C C   . GLY B 2 397 ? 179.628 195.156 113.830 1.00 40.29  ? 415  GLY C C   1 
ATOM   8897  O O   . GLY B 2 397 ? 179.137 194.035 113.629 1.00 40.29  ? 415  GLY C O   1 
ATOM   8898  N N   . ARG B 2 398 ? 179.700 195.762 115.008 1.00 40.29  ? 416  ARG C N   1 
ATOM   8899  C CA  . ARG B 2 398 ? 179.330 195.223 116.295 1.00 40.29  ? 416  ARG C CA  1 
ATOM   8900  C C   . ARG B 2 398 ? 177.871 194.871 116.355 1.00 40.29  ? 416  ARG C C   1 
ATOM   8901  O O   . ARG B 2 398 ? 177.465 193.997 117.124 1.00 40.29  ? 416  ARG C O   1 
ATOM   8902  C CB  . ARG B 2 398 ? 179.623 196.246 117.376 1.00 56.58  ? 416  ARG C CB  1 
ATOM   8903  C CG  . ARG B 2 398 ? 178.748 197.489 117.298 1.00 56.58  ? 416  ARG C CG  1 
ATOM   8904  C CD  . ARG B 2 398 ? 179.192 198.552 118.215 1.00 56.58  ? 416  ARG C CD  1 
ATOM   8905  N NE  . ARG B 2 398 ? 178.298 199.709 118.145 1.00 56.58  ? 416  ARG C NE  1 
ATOM   8906  C CZ  . ARG B 2 398 ? 178.366 200.710 117.230 1.00 56.58  ? 416  ARG C CZ  1 
ATOM   8907  N NH1 . ARG B 2 398 ? 177.481 201.692 117.275 1.00 56.58  ? 416  ARG C NH1 1 
ATOM   8908  N NH2 . ARG B 2 398 ? 179.301 200.713 116.299 1.00 56.58  ? 416  ARG C NH2 1 
ATOM   8909  N N   . ARG B 2 399 ? 177.062 195.515 115.518 1.00 40.29  ? 417  ARG C N   1 
ATOM   8910  C CA  . ARG B 2 399 ? 175.658 195.233 115.589 1.00 40.29  ? 417  ARG C CA  1 
ATOM   8911  C C   . ARG B 2 399 ? 175.480 193.785 115.197 1.00 40.29  ? 417  ARG C C   1 
ATOM   8912  O O   . ARG B 2 399 ? 174.582 193.125 115.680 1.00 40.29  ? 417  ARG C O   1 
ATOM   8913  C CB  . ARG B 2 399 ? 174.866 196.137 114.692 1.00 56.58  ? 417  ARG C CB  1 
ATOM   8914  C CG  . ARG B 2 399 ? 174.773 197.558 115.053 1.00 56.58  ? 417  ARG C CG  1 
ATOM   8915  C CD  . ARG B 2 399 ? 174.086 198.268 113.960 1.00 56.58  ? 417  ARG C CD  1 
ATOM   8916  N NE  . ARG B 2 399 ? 173.861 199.655 114.251 1.00 56.58  ? 417  ARG C NE  1 
ATOM   8917  C CZ  . ARG B 2 399 ? 173.497 200.580 113.341 1.00 56.58  ? 417  ARG C CZ  1 
ATOM   8918  N NH1 . ARG B 2 399 ? 173.291 201.827 113.730 1.00 56.58  ? 417  ARG C NH1 1 
ATOM   8919  N NH2 . ARG B 2 399 ? 173.348 200.260 112.068 1.00 56.58  ? 417  ARG C NH2 1 
ATOM   8920  N N   . LEU B 2 400 ? 176.302 193.282 114.280 1.00 40.29  ? 418  LEU C N   1 
ATOM   8921  C CA  . LEU B 2 400 ? 176.222 191.879 113.987 1.00 40.29  ? 418  LEU C CA  1 
ATOM   8922  C C   . LEU B 2 400 ? 177.000 191.161 115.028 1.00 40.29  ? 418  LEU C C   1 
ATOM   8923  O O   . LEU B 2 400 ? 176.498 190.278 115.732 1.00 40.29  ? 418  LEU C O   1 
ATOM   8924  C CB  . LEU B 2 400 ? 176.844 191.546 112.621 1.00 57.27  ? 418  LEU C CB  1 
ATOM   8925  C CG  . LEU B 2 400 ? 176.075 191.924 111.399 1.00 57.27  ? 418  LEU C CG  1 
ATOM   8926  C CD1 . LEU B 2 400 ? 176.945 191.835 110.186 1.00 57.27  ? 418  LEU C CD1 1 
ATOM   8927  C CD2 . LEU B 2 400 ? 174.922 190.885 111.221 1.00 57.27  ? 418  LEU C CD2 1 
ATOM   8928  N N   . TYR B 2 401 ? 178.224 191.599 115.216 1.00 40.29  ? 419  TYR C N   1 
ATOM   8929  C CA  . TYR B 2 401 ? 179.061 190.811 116.065 1.00 40.29  ? 419  TYR C CA  1 
ATOM   8930  C C   . TYR B 2 401 ? 178.641 190.601 117.520 1.00 40.29  ? 419  TYR C C   1 
ATOM   8931  O O   . TYR B 2 401 ? 178.602 189.461 117.988 1.00 40.29  ? 419  TYR C O   1 
ATOM   8932  C CB  . TYR B 2 401 ? 180.471 191.307 116.027 1.00 54.08  ? 419  TYR C CB  1 
ATOM   8933  C CG  . TYR B 2 401 ? 181.235 190.527 116.907 1.00 54.08  ? 419  TYR C CG  1 
ATOM   8934  C CD1 . TYR B 2 401 ? 181.468 189.247 116.555 1.00 54.08  ? 419  TYR C CD1 1 
ATOM   8935  C CD2 . TYR B 2 401 ? 181.721 191.047 118.083 1.00 54.08  ? 419  TYR C CD2 1 
ATOM   8936  C CE1 . TYR B 2 401 ? 182.165 188.468 117.342 1.00 54.08  ? 419  TYR C CE1 1 
ATOM   8937  C CE2 . TYR B 2 401 ? 182.474 190.250 118.893 1.00 54.08  ? 419  TYR C CE2 1 
ATOM   8938  C CZ  . TYR B 2 401 ? 182.709 188.955 118.521 1.00 54.08  ? 419  TYR C CZ  1 
ATOM   8939  O OH  . TYR B 2 401 ? 183.504 188.137 119.304 1.00 54.08  ? 419  TYR C OH  1 
ATOM   8940  N N   . LYS B 2 402 ? 178.336 191.655 118.257 1.00 40.29  ? 420  LYS C N   1 
ATOM   8941  C CA  . LYS B 2 402 ? 178.026 191.433 119.652 1.00 40.29  ? 420  LYS C CA  1 
ATOM   8942  C C   . LYS B 2 402 ? 176.576 191.034 119.827 1.00 40.29  ? 420  LYS C C   1 
ATOM   8943  O O   . LYS B 2 402 ? 176.248 190.262 120.727 1.00 40.29  ? 420  LYS C O   1 
ATOM   8944  C CB  . LYS B 2 402 ? 178.362 192.656 120.521 1.00 55.09  ? 420  LYS C CB  1 
ATOM   8945  C CG  . LYS B 2 402 ? 177.415 193.874 120.402 1.00 55.09  ? 420  LYS C CG  1 
ATOM   8946  C CD  . LYS B 2 402 ? 177.854 195.013 121.297 1.00 55.09  ? 420  LYS C CD  1 
ATOM   8947  C CE  . LYS B 2 402 ? 177.059 196.331 121.047 1.00 55.09  ? 420  LYS C CE  1 
ATOM   8948  N NZ  . LYS B 2 402 ? 175.580 196.231 121.343 1.00 55.09  ? 420  LYS C NZ  1 
ATOM   8949  N N   . ASP B 2 403 ? 175.701 191.552 118.973 1.00 40.29  ? 421  ASP C N   1 
ATOM   8950  C CA  . ASP B 2 403 ? 174.286 191.251 119.161 1.00 40.29  ? 421  ASP C CA  1 
ATOM   8951  C C   . ASP B 2 403 ? 173.733 190.008 118.476 1.00 40.29  ? 421  ASP C C   1 
ATOM   8952  O O   . ASP B 2 403 ? 172.781 189.419 118.996 1.00 40.29  ? 421  ASP C O   1 
ATOM   8953  C CB  . ASP B 2 403 ? 173.430 192.465 118.830 1.00 51.30  ? 421  ASP C CB  1 
ATOM   8954  C CG  . ASP B 2 403 ? 173.684 193.585 119.831 1.00 51.30  ? 421  ASP C CG  1 
ATOM   8955  O OD1 . ASP B 2 403 ? 173.418 193.377 120.989 1.00 51.30  ? 421  ASP C OD1 1 
ATOM   8956  O OD2 . ASP B 2 403 ? 174.173 194.634 119.466 1.00 51.30  ? 421  ASP C OD2 1 
ATOM   8957  N N   . PHE B 2 404 ? 174.255 189.597 117.321 1.00 40.29  ? 422  PHE C N   1 
ATOM   8958  C CA  . PHE B 2 404 ? 173.632 188.456 116.668 1.00 40.29  ? 422  PHE C CA  1 
ATOM   8959  C C   . PHE B 2 404 ? 174.570 187.278 116.429 1.00 40.29  ? 422  PHE C C   1 
ATOM   8960  O O   . PHE B 2 404 ? 174.129 186.133 116.425 1.00 40.29  ? 422  PHE C O   1 
ATOM   8961  C CB  . PHE B 2 404 ? 172.993 188.938 115.380 1.00 54.49  ? 422  PHE C CB  1 
ATOM   8962  C CG  . PHE B 2 404 ? 172.052 190.036 115.668 1.00 54.49  ? 422  PHE C CG  1 
ATOM   8963  C CD1 . PHE B 2 404 ? 170.898 189.830 116.360 1.00 54.49  ? 422  PHE C CD1 1 
ATOM   8964  C CD2 . PHE B 2 404 ? 172.356 191.287 115.310 1.00 54.49  ? 422  PHE C CD2 1 
ATOM   8965  C CE1 . PHE B 2 404 ? 170.076 190.870 116.668 1.00 54.49  ? 422  PHE C CE1 1 
ATOM   8966  C CE2 . PHE B 2 404 ? 171.558 192.336 115.619 1.00 54.49  ? 422  PHE C CE2 1 
ATOM   8967  C CZ  . PHE B 2 404 ? 170.420 192.132 116.293 1.00 54.49  ? 422  PHE C CZ  1 
ATOM   8968  N N   . VAL B 2 405 ? 175.853 187.548 116.235 1.00 40.29  ? 423  VAL C N   1 
ATOM   8969  C CA  . VAL B 2 405 ? 176.833 186.507 115.910 1.00 40.29  ? 423  VAL C CA  1 
ATOM   8970  C C   . VAL B 2 405 ? 177.091 185.524 117.027 1.00 40.29  ? 423  VAL C C   1 
ATOM   8971  O O   . VAL B 2 405 ? 177.249 184.333 116.776 1.00 40.29  ? 423  VAL C O   1 
ATOM   8972  C CB  . VAL B 2 405 ? 178.158 187.123 115.437 1.00 56.74  ? 423  VAL C CB  1 
ATOM   8973  C CG1 . VAL B 2 405 ? 179.264 186.059 115.291 1.00 56.74  ? 423  VAL C CG1 1 
ATOM   8974  C CG2 . VAL B 2 405 ? 177.925 187.800 114.060 1.00 56.74  ? 423  VAL C CG2 1 
ATOM   8975  N N   . LEU B 2 406 ? 177.205 186.005 118.245 1.00 40.29  ? 424  LEU C N   1 
ATOM   8976  C CA  . LEU B 2 406 ? 177.525 185.098 119.331 1.00 40.29  ? 424  LEU C CA  1 
ATOM   8977  C C   . LEU B 2 406 ? 176.259 184.453 119.886 1.00 40.29  ? 424  LEU C C   1 
ATOM   8978  O O   . LEU B 2 406 ? 176.233 183.300 120.359 1.00 40.29  ? 424  LEU C O   1 
ATOM   8979  C CB  . LEU B 2 406 ? 178.251 185.909 120.400 1.00 57.27  ? 424  LEU C CB  1 
ATOM   8980  C CG  . LEU B 2 406 ? 179.573 186.604 119.904 1.00 57.27  ? 424  LEU C CG  1 
ATOM   8981  C CD1 . LEU B 2 406 ? 180.106 187.472 120.996 1.00 57.27  ? 424  LEU C CD1 1 
ATOM   8982  C CD2 . LEU B 2 406 ? 180.601 185.577 119.516 1.00 57.27  ? 424  LEU C CD2 1 
ATOM   8983  N N   . ASN B 2 407 ? 175.157 185.172 119.729 1.00 40.29  ? 425  ASN C N   1 
ATOM   8984  C CA  . ASN B 2 407 ? 173.866 184.778 120.252 1.00 40.29  ? 425  ASN C CA  1 
ATOM   8985  C C   . ASN B 2 407 ? 173.127 183.847 119.312 1.00 40.29  ? 425  ASN C C   1 
ATOM   8986  O O   . ASN B 2 407 ? 172.088 184.177 118.741 1.00 40.29  ? 425  ASN C O   1 
ATOM   8987  C CB  . ASN B 2 407 ? 173.066 186.016 120.530 1.00 53.59  ? 425  ASN C CB  1 
ATOM   8988  C CG  . ASN B 2 407 ? 173.715 186.821 121.582 1.00 53.59  ? 425  ASN C CG  1 
ATOM   8989  O OD1 . ASN B 2 407 ? 174.217 186.281 122.578 1.00 53.59  ? 425  ASN C OD1 1 
ATOM   8990  N ND2 . ASN B 2 407 ? 173.738 188.103 121.395 1.00 53.59  ? 425  ASN C ND2 1 
ATOM   8991  N N   . VAL B 2 408 ? 173.687 182.669 119.187 1.00 40.29  ? 426  VAL C N   1 
ATOM   8992  C CA  . VAL B 2 408 ? 173.223 181.596 118.331 1.00 40.29  ? 426  VAL C CA  1 
ATOM   8993  C C   . VAL B 2 408 ? 172.923 180.400 119.200 1.00 40.29  ? 426  VAL C C   1 
ATOM   8994  O O   . VAL B 2 408 ? 173.683 180.149 120.118 1.00 40.29  ? 426  VAL C O   1 
ATOM   8995  C CB  . VAL B 2 408 ? 174.307 181.256 117.285 1.00 56.74  ? 426  VAL C CB  1 
ATOM   8996  C CG1 . VAL B 2 408 ? 173.884 180.061 116.425 1.00 56.74  ? 426  VAL C CG1 1 
ATOM   8997  C CG2 . VAL B 2 408 ? 174.544 182.498 116.396 1.00 56.74  ? 426  VAL C CG2 1 
ATOM   8998  N N   . LYS B 2 409 ? 171.791 179.729 119.039 1.00 40.29  ? 427  LYS C N   1 
ATOM   8999  C CA  . LYS B 2 409 ? 171.486 178.645 119.978 1.00 40.29  ? 427  LYS C CA  1 
ATOM   9000  C C   . LYS B 2 409 ? 170.509 177.622 119.448 1.00 40.29  ? 427  LYS C C   1 
ATOM   9001  O O   . LYS B 2 409 ? 169.302 177.799 119.578 1.00 40.29  ? 427  LYS C O   1 
ATOM   9002  C CB  . LYS B 2 409 ? 170.904 179.207 121.284 1.00 54.73  ? 427  LYS C CB  1 
ATOM   9003  C CG  . LYS B 2 409 ? 171.825 180.093 122.105 1.00 54.73  ? 427  LYS C CG  1 
ATOM   9004  C CD  . LYS B 2 409 ? 171.696 179.816 123.592 1.00 54.73  ? 427  LYS C CD  1 
ATOM   9005  C CE  . LYS B 2 409 ? 172.906 180.346 124.344 1.00 54.73  ? 427  LYS C CE  1 
ATOM   9006  N NZ  . LYS B 2 409 ? 172.922 179.906 125.766 1.00 54.73  ? 427  LYS C NZ  1 
ATOM   9007  N N   . PHE B 2 410 ? 171.021 176.536 118.885 1.00 40.29  ? 428  PHE C N   1 
ATOM   9008  C CA  . PHE B 2 410 ? 170.147 175.492 118.391 1.00 40.29  ? 428  PHE C CA  1 
ATOM   9009  C C   . PHE B 2 410 ? 170.847 174.187 118.212 1.00 40.29  ? 428  PHE C C   1 
ATOM   9010  O O   . PHE B 2 410 ? 171.973 173.990 118.668 1.00 40.29  ? 428  PHE C O   1 
ATOM   9011  C CB  . PHE B 2 410 ? 169.582 175.859 117.016 1.00 54.49  ? 428  PHE C CB  1 
ATOM   9012  C CG  . PHE B 2 410 ? 169.081 177.259 116.920 1.00 54.49  ? 428  PHE C CG  1 
ATOM   9013  C CD1 . PHE B 2 410 ? 169.939 178.289 116.583 1.00 54.49  ? 428  PHE C CD1 1 
ATOM   9014  C CD2 . PHE B 2 410 ? 167.755 177.547 117.179 1.00 54.49  ? 428  PHE C CD2 1 
ATOM   9015  C CE1 . PHE B 2 410 ? 169.484 179.584 116.510 1.00 54.49  ? 428  PHE C CE1 1 
ATOM   9016  C CE2 . PHE B 2 410 ? 167.291 178.841 117.104 1.00 54.49  ? 428  PHE C CE2 1 
ATOM   9017  C CZ  . PHE B 2 410 ? 168.157 179.860 116.770 1.00 54.49  ? 428  PHE C CZ  1 
ATOM   9018  N N   . ASP B 2 411 ? 170.164 173.281 117.541 1.00 40.29  ? 429  ASP C N   1 
ATOM   9019  C CA  . ASP B 2 411 ? 170.777 172.028 117.226 1.00 40.29  ? 429  ASP C CA  1 
ATOM   9020  C C   . ASP B 2 411 ? 171.174 172.190 115.792 1.00 40.29  ? 429  ASP C C   1 
ATOM   9021  O O   . ASP B 2 411 ? 170.447 172.778 114.996 1.00 40.29  ? 429  ASP C O   1 
ATOM   9022  C CB  . ASP B 2 411 ? 169.782 170.896 117.373 1.00 51.30  ? 429  ASP C CB  1 
ATOM   9023  C CG  . ASP B 2 411 ? 169.127 170.884 118.729 1.00 51.30  ? 429  ASP C CG  1 
ATOM   9024  O OD1 . ASP B 2 411 ? 169.698 171.477 119.668 1.00 51.30  ? 429  ASP C OD1 1 
ATOM   9025  O OD2 . ASP B 2 411 ? 168.043 170.282 118.857 1.00 51.30  ? 429  ASP C OD2 1 
ATOM   9026  N N   . ALA B 2 412 ? 172.337 171.678 115.453 1.00 40.29  ? 430  ALA C N   1 
ATOM   9027  C CA  . ALA B 2 412 ? 172.829 171.833 114.095 1.00 40.29  ? 430  ALA C CA  1 
ATOM   9028  C C   . ALA B 2 412 ? 172.008 171.002 113.107 1.00 40.29  ? 430  ALA C C   1 
ATOM   9029  O O   . ALA B 2 412 ? 171.635 169.859 113.403 1.00 40.29  ? 430  ALA C O   1 
ATOM   9030  C CB  . ALA B 2 412 ? 174.282 171.445 114.014 1.00 54.43  ? 430  ALA C CB  1 
ATOM   9031  N N   . PRO B 2 413 ? 171.731 171.537 111.907 1.00 40.29  ? 431  PRO C N   1 
ATOM   9032  C CA  . PRO B 2 413 ? 170.981 170.878 110.884 1.00 40.29  ? 431  PRO C CA  1 
ATOM   9033  C C   . PRO B 2 413 ? 171.808 169.734 110.411 1.00 40.29  ? 431  PRO C C   1 
ATOM   9034  O O   . PRO B 2 413 ? 173.034 169.807 110.422 1.00 40.29  ? 431  PRO C O   1 
ATOM   9035  C CB  . PRO B 2 413 ? 170.815 171.957 109.814 1.00 68.85  ? 431  PRO C CB  1 
ATOM   9036  C CG  . PRO B 2 413 ? 171.983 172.878 110.027 1.00 68.85  ? 431  PRO C CG  1 
ATOM   9037  C CD  . PRO B 2 413 ? 172.239 172.865 111.516 1.00 68.85  ? 431  PRO C CD  1 
ATOM   9038  N N   . PHE B 2 414 ? 171.138 168.681 110.005 1.00 40.29  ? 432  PHE C N   1 
ATOM   9039  C CA  . PHE B 2 414 ? 171.735 167.473 109.456 1.00 40.29  ? 432  PHE C CA  1 
ATOM   9040  C C   . PHE B 2 414 ? 172.557 166.712 110.501 1.00 40.29  ? 432  PHE C C   1 
ATOM   9041  O O   . PHE B 2 414 ? 173.184 165.700 110.180 1.00 40.29  ? 432  PHE C O   1 
ATOM   9042  C CB  . PHE B 2 414 ? 172.688 167.796 108.322 1.00 54.49  ? 432  PHE C CB  1 
ATOM   9043  C CG  . PHE B 2 414 ? 172.272 168.844 107.375 1.00 54.49  ? 432  PHE C CG  1 
ATOM   9044  C CD1 . PHE B 2 414 ? 171.185 168.713 106.554 1.00 54.49  ? 432  PHE C CD1 1 
ATOM   9045  C CD2 . PHE B 2 414 ? 173.003 170.010 107.331 1.00 54.49  ? 432  PHE C CD2 1 
ATOM   9046  C CE1 . PHE B 2 414 ? 170.832 169.737 105.706 1.00 54.49  ? 432  PHE C CE1 1 
ATOM   9047  C CE2 . PHE B 2 414 ? 172.664 171.027 106.499 1.00 54.49  ? 432  PHE C CE2 1 
ATOM   9048  C CZ  . PHE B 2 414 ? 171.578 170.904 105.685 1.00 54.49  ? 432  PHE C CZ  1 
ATOM   9049  N N   . ARG B 2 415 ? 172.507 167.146 111.759 1.00 40.29  ? 433  ARG C N   1 
ATOM   9050  C CA  . ARG B 2 415 ? 173.187 166.483 112.836 1.00 40.29  ? 433  ARG C CA  1 
ATOM   9051  C C   . ARG B 2 415 ? 172.418 165.214 113.128 1.00 40.29  ? 433  ARG C C   1 
ATOM   9052  O O   . ARG B 2 415 ? 171.205 165.211 112.942 1.00 40.29  ? 433  ARG C O   1 
ATOM   9053  C CB  . ARG B 2 415 ? 173.181 167.380 114.051 1.00 56.58  ? 433  ARG C CB  1 
ATOM   9054  C CG  . ARG B 2 415 ? 173.901 166.885 115.222 1.00 56.58  ? 433  ARG C CG  1 
ATOM   9055  C CD  . ARG B 2 415 ? 173.915 167.841 116.279 1.00 56.58  ? 433  ARG C CD  1 
ATOM   9056  N NE  . ARG B 2 415 ? 174.553 167.290 117.414 1.00 56.58  ? 433  ARG C NE  1 
ATOM   9057  C CZ  . ARG B 2 415 ? 175.875 167.271 117.634 1.00 56.58  ? 433  ARG C CZ  1 
ATOM   9058  N NH1 . ARG B 2 415 ? 176.358 166.726 118.732 1.00 56.58  ? 433  ARG C NH1 1 
ATOM   9059  N NH2 . ARG B 2 415 ? 176.710 167.788 116.752 1.00 56.58  ? 433  ARG C NH2 1 
ATOM   9060  N N   . PRO B 2 416 ? 173.055 164.121 113.568 1.00 48.31  ? 434  PRO C N   1 
ATOM   9061  C CA  . PRO B 2 416 ? 172.355 162.925 113.970 1.00 48.31  ? 434  PRO C CA  1 
ATOM   9062  C C   . PRO B 2 416 ? 171.303 163.313 115.005 1.00 48.31  ? 434  PRO C C   1 
ATOM   9063  O O   . PRO B 2 416 ? 171.585 164.045 115.951 1.00 48.31  ? 434  PRO C O   1 
ATOM   9064  C CB  . PRO B 2 416 ? 173.496 162.085 114.558 1.00 82.55  ? 434  PRO C CB  1 
ATOM   9065  C CG  . PRO B 2 416 ? 174.726 162.525 113.773 1.00 82.55  ? 434  PRO C CG  1 
ATOM   9066  C CD  . PRO B 2 416 ? 174.539 163.999 113.563 1.00 82.55  ? 434  PRO C CD  1 
ATOM   9067  N N   . ALA B 2 417 ? 170.101 162.765 114.824 1.00 54.27  ? 435  ALA C N   1 
ATOM   9068  C CA  . ALA B 2 417 ? 168.919 163.067 115.634 1.00 54.27  ? 435  ALA C CA  1 
ATOM   9069  C C   . ALA B 2 417 ? 169.054 162.697 117.094 1.00 54.27  ? 435  ALA C C   1 
ATOM   9070  O O   . ALA B 2 417 ? 168.315 163.196 117.938 1.00 54.27  ? 435  ALA C O   1 
ATOM   9071  C CB  . ALA B 2 417 ? 167.711 162.347 115.065 1.00 73.32  ? 435  ALA C CB  1 
ATOM   9072  N N   . ASP B 2 418 ? 169.948 161.781 117.391 1.00 57.70  ? 436  ASP C N   1 
ATOM   9073  C CA  . ASP B 2 418 ? 170.148 161.319 118.742 1.00 57.70  ? 436  ASP C CA  1 
ATOM   9074  C C   . ASP B 2 418 ? 170.874 162.311 119.640 1.00 57.70  ? 436  ASP C C   1 
ATOM   9075  O O   . ASP B 2 418 ? 170.882 162.146 120.864 1.00 57.70  ? 436  ASP C O   1 
ATOM   9076  C CB  . ASP B 2 418 ? 170.920 160.015 118.675 1.00 73.47  ? 436  ASP C CB  1 
ATOM   9077  C CG  . ASP B 2 418 ? 172.165 160.225 117.878 1.00 73.47  ? 436  ASP C CG  1 
ATOM   9078  O OD1 . ASP B 2 418 ? 172.008 160.380 116.676 1.00 73.47  ? 436  ASP C OD1 1 
ATOM   9079  O OD2 . ASP B 2 418 ? 173.239 160.260 118.417 1.00 73.47  ? 436  ASP C OD2 1 
ATOM   9080  N N   . THR B 2 419 ? 171.527 163.309 119.061 1.00 52.52  ? 437  THR C N   1 
ATOM   9081  C CA  . THR B 2 419 ? 172.316 164.202 119.893 1.00 52.52  ? 437  THR C CA  1 
ATOM   9082  C C   . THR B 2 419 ? 172.209 165.694 119.637 1.00 52.52  ? 437  THR C C   1 
ATOM   9083  O O   . THR B 2 419 ? 171.558 166.162 118.704 1.00 52.52  ? 437  THR C O   1 
ATOM   9084  C CB  . THR B 2 419 ? 173.754 163.742 119.862 1.00 71.89  ? 437  THR C CB  1 
ATOM   9085  O OG1 . THR B 2 419 ? 174.505 164.506 120.825 1.00 71.89  ? 437  THR C OG1 1 
ATOM   9086  C CG2 . THR B 2 419 ? 174.305 163.860 118.480 1.00 71.89  ? 437  THR C CG2 1 
ATOM   9087  N N   . HIS B 2 420 ? 172.883 166.453 120.502 1.00 47.03  ? 438  HIS C N   1 
ATOM   9088  C CA  . HIS B 2 420 ? 172.851 167.917 120.463 1.00 47.03  ? 438  HIS C CA  1 
ATOM   9089  C C   . HIS B 2 420 ? 174.204 168.578 120.662 1.00 47.03  ? 438  HIS C C   1 
ATOM   9090  O O   . HIS B 2 420 ? 175.034 168.095 121.430 1.00 47.03  ? 438  HIS C O   1 
ATOM   9091  C CB  . HIS B 2 420 ? 171.933 168.432 121.565 1.00 62.47  ? 438  HIS C CB  1 
ATOM   9092  C CG  . HIS B 2 420 ? 170.541 168.010 121.419 1.00 62.47  ? 438  HIS C CG  1 
ATOM   9093  N ND1 . HIS B 2 420 ? 169.618 168.739 120.716 1.00 62.47  ? 438  HIS C ND1 1 
ATOM   9094  C CD2 . HIS B 2 420 ? 169.892 166.919 121.880 1.00 62.47  ? 438  HIS C CD2 1 
ATOM   9095  C CE1 . HIS B 2 420 ? 168.459 168.127 120.753 1.00 62.47  ? 438  HIS C CE1 1 
ATOM   9096  N NE2 . HIS B 2 420 ? 168.594 167.013 121.458 1.00 62.47  ? 438  HIS C NE2 1 
ATOM   9097  N N   . ASN B 2 421 ? 174.387 169.728 120.020 1.00 40.29  ? 439  ASN C N   1 
ATOM   9098  C CA  . ASN B 2 421 ? 175.576 170.525 120.231 1.00 40.29  ? 439  ASN C CA  1 
ATOM   9099  C C   . ASN B 2 421 ? 175.353 171.951 120.702 1.00 40.29  ? 439  ASN C C   1 
ATOM   9100  O O   . ASN B 2 421 ? 176.332 172.640 120.976 1.00 40.29  ? 439  ASN C O   1 
ATOM   9101  C CB  . ASN B 2 421 ? 176.408 170.496 118.993 1.00 53.59  ? 439  ASN C CB  1 
ATOM   9102  C CG  . ASN B 2 421 ? 175.641 170.913 117.748 1.00 53.59  ? 439  ASN C CG  1 
ATOM   9103  O OD1 . ASN B 2 421 ? 174.393 171.135 117.733 1.00 53.59  ? 439  ASN C OD1 1 
ATOM   9104  N ND2 . ASN B 2 421 ? 176.383 170.996 116.682 1.00 53.59  ? 439  ASN C ND2 1 
ATOM   9105  N N   . GLU B 2 422 ? 174.095 172.380 120.861 1.00 40.29  ? 440  GLU C N   1 
ATOM   9106  C CA  . GLU B 2 422 ? 173.810 173.734 121.328 1.00 40.29  ? 440  GLU C CA  1 
ATOM   9107  C C   . GLU B 2 422 ? 174.772 174.738 120.727 1.00 40.29  ? 440  GLU C C   1 
ATOM   9108  O O   . GLU B 2 422 ? 175.569 175.346 121.458 1.00 40.29  ? 440  GLU C O   1 
ATOM   9109  C CB  . GLU B 2 422 ? 173.880 173.809 122.849 1.00 53.10  ? 440  GLU C CB  1 
ATOM   9110  C CG  . GLU B 2 422 ? 172.859 172.975 123.605 1.00 53.10  ? 440  GLU C CG  1 
ATOM   9111  C CD  . GLU B 2 422 ? 171.442 173.505 123.474 1.00 53.10  ? 440  GLU C CD  1 
ATOM   9112  O OE1 . GLU B 2 422 ? 171.273 174.574 122.930 1.00 53.10  ? 440  GLU C OE1 1 
ATOM   9113  O OE2 . GLU B 2 422 ? 170.541 172.852 123.942 1.00 53.10  ? 440  GLU C OE2 1 
ATOM   9114  N N   . VAL B 2 423 ? 174.734 174.910 119.404 1.00 40.29  ? 441  VAL C N   1 
ATOM   9115  C CA  . VAL B 2 423 ? 175.755 175.764 118.829 1.00 40.29  ? 441  VAL C CA  1 
ATOM   9116  C C   . VAL B 2 423 ? 175.496 177.134 119.352 1.00 40.29  ? 441  VAL C C   1 
ATOM   9117  O O   . VAL B 2 423 ? 174.410 177.663 119.162 1.00 40.29  ? 441  VAL C O   1 
ATOM   9118  C CB  . VAL B 2 423 ? 175.672 175.817 117.291 1.00 56.74  ? 441  VAL C CB  1 
ATOM   9119  C CG1 . VAL B 2 423 ? 176.715 176.801 116.708 1.00 56.74  ? 441  VAL C CG1 1 
ATOM   9120  C CG2 . VAL B 2 423 ? 175.832 174.407 116.726 1.00 56.74  ? 441  VAL C CG2 1 
ATOM   9121  N N   . ARG B 2 424 ? 176.516 177.668 120.007 1.00 40.29  ? 442  ARG C N   1 
ATOM   9122  C CA  . ARG B 2 424 ? 176.581 178.939 120.693 1.00 40.29  ? 442  ARG C CA  1 
ATOM   9123  C C   . ARG B 2 424 ? 178.015 179.355 120.770 1.00 40.29  ? 442  ARG C C   1 
ATOM   9124  O O   . ARG B 2 424 ? 178.904 178.499 120.653 1.00 40.29  ? 442  ARG C O   1 
ATOM   9125  C CB  . ARG B 2 424 ? 176.137 178.795 122.137 1.00 54.67  ? 442  ARG C CB  1 
ATOM   9126  C CG  . ARG B 2 424 ? 174.706 178.496 122.433 1.00 54.67  ? 442  ARG C CG  1 
ATOM   9127  C CD  . ARG B 2 424 ? 174.546 178.154 123.832 1.00 54.67  ? 442  ARG C CD  1 
ATOM   9128  N NE  . ARG B 2 424 ? 175.173 176.864 124.124 1.00 54.67  ? 442  ARG C NE  1 
ATOM   9129  C CZ  . ARG B 2 424 ? 175.436 176.381 125.364 1.00 54.67  ? 442  ARG C CZ  1 
ATOM   9130  N NH1 . ARG B 2 424 ? 175.981 175.182 125.498 1.00 54.67  ? 442  ARG C NH1 1 
ATOM   9131  N NH2 . ARG B 2 424 ? 175.147 177.093 126.438 1.00 54.67  ? 442  ARG C NH2 1 
ATOM   9132  N N   . PHE B 2 425 ? 178.243 180.635 121.032 1.00 40.29  ? 443  PHE C N   1 
ATOM   9133  C CA  . PHE B 2 425 ? 179.578 181.111 121.296 1.00 40.29  ? 443  PHE C CA  1 
ATOM   9134  C C   . PHE B 2 425 ? 179.564 181.861 122.596 1.00 40.29  ? 443  PHE C C   1 
ATOM   9135  O O   . PHE B 2 425 ? 178.553 182.468 122.955 1.00 40.29  ? 443  PHE C O   1 
ATOM   9136  C CB  . PHE B 2 425 ? 180.012 182.067 120.227 1.00 54.49  ? 443  PHE C CB  1 
ATOM   9137  C CG  . PHE B 2 425 ? 179.988 181.481 118.918 1.00 54.49  ? 443  PHE C CG  1 
ATOM   9138  C CD1 . PHE B 2 425 ? 178.827 181.525 118.159 1.00 54.49  ? 443  PHE C CD1 1 
ATOM   9139  C CD2 . PHE B 2 425 ? 181.083 180.867 118.412 1.00 54.49  ? 443  PHE C CD2 1 
ATOM   9140  C CE1 . PHE B 2 425 ? 178.782 180.951 116.934 1.00 54.49  ? 443  PHE C CE1 1 
ATOM   9141  C CE2 . PHE B 2 425 ? 181.042 180.295 117.191 1.00 54.49  ? 443  PHE C CE2 1 
ATOM   9142  C CZ  . PHE B 2 425 ? 179.895 180.326 116.444 1.00 54.49  ? 443  PHE C CZ  1 
ATOM   9143  N N   . ASP B 2 426 ? 180.683 181.880 123.290 1.00 40.29  ? 444  ASP C N   1 
ATOM   9144  C CA  . ASP B 2 426 ? 180.743 182.716 124.471 1.00 40.29  ? 444  ASP C CA  1 
ATOM   9145  C C   . ASP B 2 426 ? 181.051 184.130 124.007 1.00 40.29  ? 444  ASP C C   1 
ATOM   9146  O O   . ASP B 2 426 ? 181.042 184.426 122.808 1.00 40.29  ? 444  ASP C O   1 
ATOM   9147  C CB  . ASP B 2 426 ? 181.778 182.258 125.505 1.00 51.30  ? 444  ASP C CB  1 
ATOM   9148  C CG  . ASP B 2 426 ? 183.197 182.443 125.081 1.00 51.30  ? 444  ASP C CG  1 
ATOM   9149  O OD1 . ASP B 2 426 ? 183.427 183.005 124.026 1.00 51.30  ? 444  ASP C OD1 1 
ATOM   9150  O OD2 . ASP B 2 426 ? 184.067 182.069 125.811 1.00 51.30  ? 444  ASP C OD2 1 
ATOM   9151  N N   . ARG B 2 427 ? 181.306 185.017 124.953 1.00 40.29  ? 445  ARG C N   1 
ATOM   9152  C CA  . ARG B 2 427 ? 181.524 186.419 124.650 1.00 40.29  ? 445  ARG C CA  1 
ATOM   9153  C C   . ARG B 2 427 ? 182.786 186.696 123.840 1.00 40.29  ? 445  ARG C C   1 
ATOM   9154  O O   . ARG B 2 427 ? 182.974 187.818 123.358 1.00 40.29  ? 445  ARG C O   1 
ATOM   9155  C CB  . ARG B 2 427 ? 181.532 187.243 125.917 1.00 54.41  ? 445  ARG C CB  1 
ATOM   9156  C CG  . ARG B 2 427 ? 182.677 187.019 126.852 1.00 54.41  ? 445  ARG C CG  1 
ATOM   9157  C CD  . ARG B 2 427 ? 182.457 187.790 128.092 1.00 54.41  ? 445  ARG C CD  1 
ATOM   9158  N NE  . ARG B 2 427 ? 183.535 187.651 129.044 1.00 54.41  ? 445  ARG C NE  1 
ATOM   9159  C CZ  . ARG B 2 427 ? 183.673 186.645 129.937 1.00 54.41  ? 445  ARG C CZ  1 
ATOM   9160  N NH1 . ARG B 2 427 ? 184.702 186.648 130.766 1.00 54.41  ? 445  ARG C NH1 1 
ATOM   9161  N NH2 . ARG B 2 427 ? 182.797 185.662 129.991 1.00 54.41  ? 445  ARG C NH2 1 
ATOM   9162  N N   . PHE B 2 428 ? 183.682 185.723 123.744 1.00 40.29  ? 446  PHE C N   1 
ATOM   9163  C CA  . PHE B 2 428 ? 184.917 185.873 123.017 1.00 40.29  ? 446  PHE C CA  1 
ATOM   9164  C C   . PHE B 2 428 ? 184.848 185.131 121.709 1.00 40.29  ? 446  PHE C C   1 
ATOM   9165  O O   . PHE B 2 428 ? 185.867 184.953 121.049 1.00 40.29  ? 446  PHE C O   1 
ATOM   9166  C CB  . PHE B 2 428 ? 186.060 185.266 123.792 1.00 54.49  ? 446  PHE C CB  1 
ATOM   9167  C CG  . PHE B 2 428 ? 186.228 185.851 125.074 1.00 54.49  ? 446  PHE C CG  1 
ATOM   9168  C CD1 . PHE B 2 428 ? 186.853 187.051 125.225 1.00 54.49  ? 446  PHE C CD1 1 
ATOM   9169  C CD2 . PHE B 2 428 ? 185.754 185.189 126.168 1.00 54.49  ? 446  PHE C CD2 1 
ATOM   9170  C CE1 . PHE B 2 428 ? 187.001 187.587 126.463 1.00 54.49  ? 446  PHE C CE1 1 
ATOM   9171  C CE2 . PHE B 2 428 ? 185.903 185.707 127.397 1.00 54.49  ? 446  PHE C CE2 1 
ATOM   9172  C CZ  . PHE B 2 428 ? 186.527 186.912 127.553 1.00 54.49  ? 446  PHE C CZ  1 
ATOM   9173  N N   . GLY B 2 429 ? 183.683 184.611 121.355 1.00 40.29  ? 447  GLY C N   1 
ATOM   9174  C CA  . GLY B 2 429 ? 183.619 183.870 120.125 1.00 40.29  ? 447  GLY C CA  1 
ATOM   9175  C C   . GLY B 2 429 ? 184.065 182.439 120.295 1.00 40.29  ? 447  GLY C C   1 
ATOM   9176  O O   . GLY B 2 429 ? 184.365 181.755 119.323 1.00 40.29  ? 447  GLY C O   1 
ATOM   9177  N N   . ASP B 2 430 ? 184.180 181.917 121.511 1.00 40.29  ? 448  ASP C N   1 
ATOM   9178  C CA  . ASP B 2 430 ? 184.513 180.505 121.662 1.00 40.29  ? 448  ASP C CA  1 
ATOM   9179  C C   . ASP B 2 430 ? 183.301 179.644 121.322 1.00 40.29  ? 448  ASP C C   1 
ATOM   9180  O O   . ASP B 2 430 ? 182.318 179.644 122.061 1.00 40.29  ? 448  ASP C O   1 
ATOM   9181  C CB  . ASP B 2 430 ? 185.002 180.196 123.075 1.00 51.30  ? 448  ASP C CB  1 
ATOM   9182  C CG  . ASP B 2 430 ? 185.703 178.838 123.109 1.00 51.30  ? 448  ASP C CG  1 
ATOM   9183  O OD1 . ASP B 2 430 ? 186.507 178.584 122.194 1.00 51.30  ? 448  ASP C OD1 1 
ATOM   9184  O OD2 . ASP B 2 430 ? 185.469 178.057 124.059 1.00 51.30  ? 448  ASP C OD2 1 
ATOM   9185  N N   . GLY B 2 431 ? 183.349 178.917 120.210 1.00 40.29  ? 449  GLY C N   1 
ATOM   9186  C CA  . GLY B 2 431 ? 182.285 178.005 119.811 1.00 40.29  ? 449  GLY C CA  1 
ATOM   9187  C C   . GLY B 2 431 ? 182.190 176.834 120.777 1.00 40.29  ? 449  GLY C C   1 
ATOM   9188  O O   . GLY B 2 431 ? 183.121 176.047 120.916 1.00 40.29  ? 449  GLY C O   1 
ATOM   9189  N N   . ILE B 2 432 ? 181.060 176.717 121.455 1.00 40.29  ? 450  ILE C N   1 
ATOM   9190  C CA  . ILE B 2 432 ? 180.833 175.691 122.474 1.00 40.29  ? 450  ILE C CA  1 
ATOM   9191  C C   . ILE B 2 432 ? 180.607 174.325 121.792 1.00 40.29  ? 450  ILE C C   1 
ATOM   9192  O O   . ILE B 2 432 ? 179.942 174.273 120.757 1.00 40.29  ? 450  ILE C O   1 
ATOM   9193  C CB  . ILE B 2 432 ? 179.677 176.140 123.389 1.00 57.27  ? 450  ILE C CB  1 
ATOM   9194  C CG1 . ILE B 2 432 ? 179.921 177.583 123.907 1.00 57.27  ? 450  ILE C CG1 1 
ATOM   9195  C CG2 . ILE B 2 432 ? 179.556 175.145 124.549 1.00 57.27  ? 450  ILE C CG2 1 
ATOM   9196  C CD1 . ILE B 2 432 ? 178.874 178.136 124.875 1.00 57.27  ? 450  ILE C CD1 1 
ATOM   9197  N N   . GLY B 2 433 ? 181.172 173.225 122.314 1.00 40.29  ? 451  GLY C N   1 
ATOM   9198  C CA  . GLY B 2 433 ? 181.293 171.956 121.566 1.00 40.29  ? 451  GLY C CA  1 
ATOM   9199  C C   . GLY B 2 433 ? 181.104 170.653 122.357 1.00 40.29  ? 451  GLY C C   1 
ATOM   9200  O O   . GLY B 2 433 ? 180.474 170.618 123.413 1.00 40.29  ? 451  GLY C O   1 
ATOM   9201  N N   . ARG B 2 434 ? 181.579 169.535 121.796 1.00 40.29  ? 452  ARG C N   1 
ATOM   9202  C CA  . ARG B 2 434 ? 181.352 168.171 122.301 1.00 40.29  ? 452  ARG C CA  1 
ATOM   9203  C C   . ARG B 2 434 ? 182.573 167.306 122.103 1.00 40.29  ? 452  ARG C C   1 
ATOM   9204  O O   . ARG B 2 434 ? 183.206 167.376 121.058 1.00 40.29  ? 452  ARG C O   1 
ATOM   9205  C CB  . ARG B 2 434 ? 180.214 167.516 121.511 1.00 53.44  ? 452  ARG C CB  1 
ATOM   9206  C CG  . ARG B 2 434 ? 178.849 168.174 121.693 1.00 53.44  ? 452  ARG C CG  1 
ATOM   9207  C CD  . ARG B 2 434 ? 178.331 167.953 123.106 1.00 53.44  ? 452  ARG C CD  1 
ATOM   9208  N NE  . ARG B 2 434 ? 177.050 168.640 123.286 1.00 53.44  ? 452  ARG C NE  1 
ATOM   9209  C CZ  . ARG B 2 434 ? 176.849 169.752 123.962 1.00 53.44  ? 452  ARG C CZ  1 
ATOM   9210  N NH1 . ARG B 2 434 ? 175.638 170.116 124.247 1.00 53.44  ? 452  ARG C NH1 1 
ATOM   9211  N NH2 . ARG B 2 434 ? 177.834 170.496 124.369 1.00 53.44  ? 452  ARG C NH2 1 
ATOM   9212  N N   . TYR B 2 435 ? 182.889 166.436 123.051 1.00 40.29  ? 453  TYR C N   1 
ATOM   9213  C CA  . TYR B 2 435 ? 184.170 165.735 123.008 1.00 40.29  ? 453  TYR C CA  1 
ATOM   9214  C C   . TYR B 2 435 ? 184.065 164.313 123.515 1.00 40.29  ? 453  TYR C C   1 
ATOM   9215  O O   . TYR B 2 435 ? 183.462 164.074 124.554 1.00 40.29  ? 453  TYR C O   1 
ATOM   9216  C CB  . TYR B 2 435 ? 185.225 166.521 123.783 1.00 54.08  ? 453  TYR C CB  1 
ATOM   9217  C CG  . TYR B 2 435 ? 185.514 167.865 123.168 1.00 54.08  ? 453  TYR C CG  1 
ATOM   9218  C CD1 . TYR B 2 435 ? 185.630 167.992 121.780 1.00 54.08  ? 453  TYR C CD1 1 
ATOM   9219  C CD2 . TYR B 2 435 ? 185.463 169.012 123.971 1.00 54.08  ? 453  TYR C CD2 1 
ATOM   9220  C CE1 . TYR B 2 435 ? 185.675 169.266 121.196 1.00 54.08  ? 453  TYR C CE1 1 
ATOM   9221  C CE2 . TYR B 2 435 ? 185.524 170.290 123.396 1.00 54.08  ? 453  TYR C CE2 1 
ATOM   9222  C CZ  . TYR B 2 435 ? 185.641 170.413 122.005 1.00 54.08  ? 453  TYR C CZ  1 
ATOM   9223  O OH  . TYR B 2 435 ? 185.740 171.646 121.453 1.00 54.08  ? 453  TYR C OH  1 
ATOM   9224  N N   . ASN B 2 436 ? 184.663 163.357 122.819 1.00 40.29  ? 454  ASN C N   1 
ATOM   9225  C CA  . ASN B 2 436 ? 184.601 161.975 123.238 1.00 40.29  ? 454  ASN C CA  1 
ATOM   9226  C C   . ASN B 2 436 ? 185.782 161.653 124.096 1.00 40.29  ? 454  ASN C C   1 
ATOM   9227  O O   . ASN B 2 436 ? 186.923 162.000 123.766 1.00 40.29  ? 454  ASN C O   1 
ATOM   9228  C CB  . ASN B 2 436 ? 184.531 161.010 122.082 1.00 53.59  ? 454  ASN C CB  1 
ATOM   9229  C CG  . ASN B 2 436 ? 183.252 161.062 121.342 1.00 53.59  ? 454  ASN C CG  1 
ATOM   9230  O OD1 . ASN B 2 436 ? 182.173 161.343 121.883 1.00 53.59  ? 454  ASN C OD1 1 
ATOM   9231  N ND2 . ASN B 2 436 ? 183.333 160.757 120.080 1.00 53.59  ? 454  ASN C ND2 1 
ATOM   9232  N N   . ILE B 2 437 ? 185.513 160.992 125.205 1.00 40.29  ? 455  ILE C N   1 
ATOM   9233  C CA  . ILE B 2 437 ? 186.568 160.578 126.091 1.00 40.29  ? 455  ILE C CA  1 
ATOM   9234  C C   . ILE B 2 437 ? 186.637 159.076 126.014 1.00 40.29  ? 455  ILE C C   1 
ATOM   9235  O O   . ILE B 2 437 ? 185.667 158.371 126.321 1.00 40.29  ? 455  ILE C O   1 
ATOM   9236  C CB  . ILE B 2 437 ? 186.307 161.059 127.511 1.00 57.27  ? 455  ILE C CB  1 
ATOM   9237  C CG1 . ILE B 2 437 ? 186.045 162.593 127.523 1.00 57.27  ? 455  ILE C CG1 1 
ATOM   9238  C CG2 . ILE B 2 437 ? 187.479 160.691 128.347 1.00 57.27  ? 455  ILE C CG2 1 
ATOM   9239  C CD1 . ILE B 2 437 ? 187.144 163.478 127.016 1.00 57.27  ? 455  ILE C CD1 1 
ATOM   9240  N N   . PHE B 2 438 ? 187.752 158.505 125.607 1.00 40.29  ? 456  PHE C N   1 
ATOM   9241  C CA  . PHE B 2 438 ? 187.772 157.079 125.304 1.00 40.29  ? 456  PHE C CA  1 
ATOM   9242  C C   . PHE B 2 438 ? 189.138 156.489 125.551 1.00 40.29  ? 456  PHE C C   1 
ATOM   9243  O O   . PHE B 2 438 ? 190.138 157.199 125.519 1.00 40.29  ? 456  PHE C O   1 
ATOM   9244  C CB  . PHE B 2 438 ? 187.338 156.881 123.858 1.00 54.49  ? 456  PHE C CB  1 
ATOM   9245  C CG  . PHE B 2 438 ? 188.080 157.719 122.884 1.00 54.49  ? 456  PHE C CG  1 
ATOM   9246  C CD1 . PHE B 2 438 ? 187.606 159.006 122.619 1.00 54.49  ? 456  PHE C CD1 1 
ATOM   9247  C CD2 . PHE B 2 438 ? 189.205 157.217 122.235 1.00 54.49  ? 456  PHE C CD2 1 
ATOM   9248  C CE1 . PHE B 2 438 ? 188.251 159.809 121.681 1.00 54.49  ? 456  PHE C CE1 1 
ATOM   9249  C CE2 . PHE B 2 438 ? 189.825 158.003 121.261 1.00 54.49  ? 456  PHE C CE2 1 
ATOM   9250  C CZ  . PHE B 2 438 ? 189.358 159.300 120.985 1.00 54.49  ? 456  PHE C CZ  1 
ATOM   9251  N N   . THR B 2 439 ? 189.182 155.185 125.808 1.00 40.29  ? 457  THR C N   1 
ATOM   9252  C CA  . THR B 2 439 ? 190.434 154.515 126.131 1.00 40.29  ? 457  THR C CA  1 
ATOM   9253  C C   . THR B 2 439 ? 190.845 153.491 125.118 1.00 40.29  ? 457  THR C C   1 
ATOM   9254  O O   . THR B 2 439 ? 190.045 153.075 124.286 1.00 40.29  ? 457  THR C O   1 
ATOM   9255  C CB  . THR B 2 439 ? 190.320 153.820 127.492 1.00 55.15  ? 457  THR C CB  1 
ATOM   9256  O OG1 . THR B 2 439 ? 191.599 153.350 127.886 1.00 55.15  ? 457  THR C OG1 1 
ATOM   9257  C CG2 . THR B 2 439 ? 189.353 152.628 127.413 1.00 55.15  ? 457  THR C CG2 1 
ATOM   9258  N N   . TYR B 2 440 ? 192.109 153.069 125.106 1.00 40.29  ? 458  TYR C N   1 
ATOM   9259  C CA  . TYR B 2 440 ? 192.584 152.014 124.212 1.00 40.29  ? 458  TYR C CA  1 
ATOM   9260  C C   . TYR B 2 440 ? 192.585 150.656 124.913 1.00 40.29  ? 458  TYR C C   1 
ATOM   9261  O O   . TYR B 2 440 ? 193.399 150.397 125.795 1.00 40.29  ? 458  TYR C O   1 
ATOM   9262  C CB  . TYR B 2 440 ? 193.978 152.382 123.731 1.00 54.08  ? 458  TYR C CB  1 
ATOM   9263  C CG  . TYR B 2 440 ? 194.460 151.554 122.568 1.00 54.08  ? 458  TYR C CG  1 
ATOM   9264  C CD1 . TYR B 2 440 ? 193.743 151.570 121.359 1.00 54.08  ? 458  TYR C CD1 1 
ATOM   9265  C CD2 . TYR B 2 440 ? 195.659 150.832 122.662 1.00 54.08  ? 458  TYR C CD2 1 
ATOM   9266  C CE1 . TYR B 2 440 ? 194.271 150.950 120.220 1.00 54.08  ? 458  TYR C CE1 1 
ATOM   9267  C CE2 . TYR B 2 440 ? 196.195 150.213 121.523 1.00 54.08  ? 458  TYR C CE2 1 
ATOM   9268  C CZ  . TYR B 2 440 ? 195.515 150.302 120.291 1.00 54.08  ? 458  TYR C CZ  1 
ATOM   9269  O OH  . TYR B 2 440 ? 196.047 149.749 119.176 1.00 54.08  ? 458  TYR C OH  1 
ATOM   9270  N N   . LEU B 2 441 ? 191.650 149.789 124.543 1.00 40.29  ? 459  LEU C N   1 
ATOM   9271  C CA  . LEU B 2 441 ? 191.452 148.527 125.213 1.00 40.29  ? 459  LEU C CA  1 
ATOM   9272  C C   . LEU B 2 441 ? 192.337 147.416 124.752 1.00 40.29  ? 459  LEU C C   1 
ATOM   9273  O O   . LEU B 2 441 ? 192.576 147.237 123.557 1.00 40.29  ? 459  LEU C O   1 
ATOM   9274  C CB  . LEU B 2 441 ? 190.038 148.013 124.981 1.00 57.27  ? 459  LEU C CB  1 
ATOM   9275  C CG  . LEU B 2 441 ? 188.874 148.845 125.459 1.00 57.27  ? 459  LEU C CG  1 
ATOM   9276  C CD1 . LEU B 2 441 ? 187.625 148.129 125.016 1.00 57.27  ? 459  LEU C CD1 1 
ATOM   9277  C CD2 . LEU B 2 441 ? 188.897 149.021 126.988 1.00 57.27  ? 459  LEU C CD2 1 
ATOM   9278  N N   . ARG B 2 442 ? 192.685 146.576 125.714 1.00 40.29  ? 460  ARG C N   1 
ATOM   9279  C CA  . ARG B 2 442 ? 193.388 145.349 125.457 1.00 40.29  ? 460  ARG C CA  1 
ATOM   9280  C C   . ARG B 2 442 ? 192.450 144.437 124.728 1.00 40.29  ? 460  ARG C C   1 
ATOM   9281  O O   . ARG B 2 442 ? 191.271 144.339 125.065 1.00 40.29  ? 460  ARG C O   1 
ATOM   9282  C CB  . ARG B 2 442 ? 193.801 144.651 126.736 1.00 58.86  ? 460  ARG C CB  1 
ATOM   9283  C CG  . ARG B 2 442 ? 194.552 143.322 126.534 1.00 58.86  ? 460  ARG C CG  1 
ATOM   9284  C CD  . ARG B 2 442 ? 194.956 142.720 127.812 1.00 58.86  ? 460  ARG C CD  1 
ATOM   9285  N NE  . ARG B 2 442 ? 195.932 143.528 128.495 1.00 58.86  ? 460  ARG C NE  1 
ATOM   9286  C CZ  . ARG B 2 442 ? 196.316 143.382 129.780 1.00 58.86  ? 460  ARG C CZ  1 
ATOM   9287  N NH1 . ARG B 2 442 ? 197.200 144.232 130.273 1.00 58.86  ? 460  ARG C NH1 1 
ATOM   9288  N NH2 . ARG B 2 442 ? 195.817 142.416 130.540 1.00 58.86  ? 460  ARG C NH2 1 
ATOM   9289  N N   . ALA B 2 443 ? 192.975 143.722 123.776 1.00 54.42  ? 461  ALA C N   1 
ATOM   9290  C CA  . ALA B 2 443 ? 192.210 142.761 123.036 1.00 54.42  ? 461  ALA C CA  1 
ATOM   9291  C C   . ALA B 2 443 ? 193.004 141.485 122.959 1.00 54.42  ? 461  ALA C C   1 
ATOM   9292  O O   . ALA B 2 443 ? 193.748 141.251 122.018 1.00 54.42  ? 461  ALA C O   1 
ATOM   9293  C CB  . ALA B 2 443 ? 191.881 143.277 121.657 1.00 73.52  ? 461  ALA C CB  1 
ATOM   9294  N N   . GLY B 2 444 ? 192.857 140.619 123.950 1.00 62.95  ? 462  GLY C N   1 
ATOM   9295  C CA  . GLY B 2 444 ? 193.681 139.411 123.976 1.00 62.95  ? 462  GLY C CA  1 
ATOM   9296  C C   . GLY B 2 444 ? 193.338 138.482 122.807 1.00 62.95  ? 462  GLY C C   1 
ATOM   9297  O O   . GLY B 2 444 ? 194.113 137.595 122.445 1.00 62.95  ? 462  GLY C O   1 
ATOM   9298  N N   . SER B 2 445 ? 192.168 138.714 122.225 1.00 74.25  ? 463  SER C N   1 
ATOM   9299  C CA  . SER B 2 445 ? 191.607 137.995 121.103 1.00 74.25  ? 463  SER C CA  1 
ATOM   9300  C C   . SER B 2 445 ? 191.660 138.784 119.789 1.00 74.25  ? 463  SER C C   1 
ATOM   9301  O O   . SER B 2 445 ? 191.014 138.398 118.810 1.00 74.25  ? 463  SER C O   1 
ATOM   9302  C CB  . SER B 2 445 ? 190.166 137.657 121.415 1.00 98.90  ? 463  SER C CB  1 
ATOM   9303  O OG  . SER B 2 445 ? 189.412 138.831 121.617 1.00 98.90  ? 463  SER C OG  1 
ATOM   9304  N N   . GLY B 2 446 ? 192.388 139.902 119.747 1.00 70.37  ? 464  GLY C N   1 
ATOM   9305  C CA  . GLY B 2 446 ? 192.390 140.708 118.528 1.00 70.37  ? 464  GLY C CA  1 
ATOM   9306  C C   . GLY B 2 446 ? 193.232 141.966 118.647 1.00 70.37  ? 464  GLY C C   1 
ATOM   9307  O O   . GLY B 2 446 ? 194.206 142.012 119.391 1.00 70.37  ? 464  GLY C O   1 
ATOM   9308  N N   . ARG B 2 447 ? 192.926 142.951 117.816 1.00 60.53  ? 465  ARG C N   1 
ATOM   9309  C CA  . ARG B 2 447 ? 193.672 144.199 117.832 1.00 60.53  ? 465  ARG C CA  1 
ATOM   9310  C C   . ARG B 2 447 ? 193.091 145.080 118.893 1.00 60.53  ? 465  ARG C C   1 
ATOM   9311  O O   . ARG B 2 447 ? 191.895 145.000 119.176 1.00 60.53  ? 465  ARG C O   1 
ATOM   9312  C CB  . ARG B 2 447 ? 193.632 144.878 116.475 1.00 88.49  ? 465  ARG C CB  1 
ATOM   9313  C CG  . ARG B 2 447 ? 194.324 144.105 115.350 1.00 88.49  ? 465  ARG C CG  1 
ATOM   9314  C CD  . ARG B 2 447 ? 195.805 144.424 115.267 1.00 88.49  ? 465  ARG C CD  1 
ATOM   9315  N NE  . ARG B 2 447 ? 196.570 143.987 116.437 1.00 88.49  ? 465  ARG C NE  1 
ATOM   9316  C CZ  . ARG B 2 447 ? 197.032 142.736 116.682 1.00 88.49  ? 465  ARG C CZ  1 
ATOM   9317  N NH1 . ARG B 2 447 ? 197.716 142.521 117.800 1.00 88.49  ? 465  ARG C NH1 1 
ATOM   9318  N NH2 . ARG B 2 447 ? 196.811 141.744 115.831 1.00 88.49  ? 465  ARG C NH2 1 
ATOM   9319  N N   . TYR B 2 448 ? 193.924 145.914 119.487 1.00 43.48  ? 466  TYR C N   1 
ATOM   9320  C CA  . TYR B 2 448 ? 193.456 146.773 120.548 1.00 43.48  ? 466  TYR C CA  1 
ATOM   9321  C C   . TYR B 2 448 ? 192.610 147.854 119.943 1.00 43.48  ? 466  TYR C C   1 
ATOM   9322  O O   . TYR B 2 448 ? 192.883 148.321 118.833 1.00 43.48  ? 466  TYR C O   1 
ATOM   9323  C CB  . TYR B 2 448 ? 194.623 147.318 121.304 1.00 58.36  ? 466  TYR C CB  1 
ATOM   9324  C CG  . TYR B 2 448 ? 195.385 146.325 122.142 1.00 58.36  ? 466  TYR C CG  1 
ATOM   9325  C CD1 . TYR B 2 448 ? 195.364 144.916 121.940 1.00 58.36  ? 466  TYR C CD1 1 
ATOM   9326  C CD2 . TYR B 2 448 ? 196.166 146.823 123.109 1.00 58.36  ? 466  TYR C CD2 1 
ATOM   9327  C CE1 . TYR B 2 448 ? 196.120 144.107 122.733 1.00 58.36  ? 466  TYR C CE1 1 
ATOM   9328  C CE2 . TYR B 2 448 ? 196.906 145.993 123.852 1.00 58.36  ? 466  TYR C CE2 1 
ATOM   9329  C CZ  . TYR B 2 448 ? 196.892 144.679 123.692 1.00 58.36  ? 466  TYR C CZ  1 
ATOM   9330  O OH  . TYR B 2 448 ? 197.645 143.936 124.543 1.00 58.36  ? 466  TYR C OH  1 
ATOM   9331  N N   . ARG B 2 449 ? 191.563 148.258 120.664 1.00 40.29  ? 467  ARG C N   1 
ATOM   9332  C CA  . ARG B 2 449 ? 190.513 149.117 120.116 1.00 40.29  ? 467  ARG C CA  1 
ATOM   9333  C C   . ARG B 2 449 ? 190.171 150.272 121.026 1.00 40.29  ? 467  ARG C C   1 
ATOM   9334  O O   . ARG B 2 449 ? 190.111 150.126 122.241 1.00 40.29  ? 467  ARG C O   1 
ATOM   9335  C CB  . ARG B 2 449 ? 189.276 148.286 119.758 1.00 56.58  ? 467  ARG C CB  1 
ATOM   9336  C CG  . ARG B 2 449 ? 188.484 147.792 120.974 1.00 56.58  ? 467  ARG C CG  1 
ATOM   9337  C CD  . ARG B 2 449 ? 187.272 146.982 120.508 1.00 56.58  ? 467  ARG C CD  1 
ATOM   9338  N NE  . ARG B 2 449 ? 186.312 146.776 121.603 1.00 56.58  ? 467  ARG C NE  1 
ATOM   9339  C CZ  . ARG B 2 449 ? 185.356 147.604 121.978 1.00 56.58  ? 467  ARG C CZ  1 
ATOM   9340  N NH1 . ARG B 2 449 ? 184.659 147.351 123.037 1.00 56.58  ? 467  ARG C NH1 1 
ATOM   9341  N NH2 . ARG B 2 449 ? 185.071 148.701 121.345 1.00 56.58  ? 467  ARG C NH2 1 
ATOM   9342  N N   . TYR B 2 450 ? 189.937 151.436 120.444 1.00 40.29  ? 468  TYR C N   1 
ATOM   9343  C CA  . TYR B 2 450 ? 189.411 152.536 121.225 1.00 40.29  ? 468  TYR C CA  1 
ATOM   9344  C C   . TYR B 2 450 ? 187.993 152.219 121.682 1.00 40.29  ? 468  TYR C C   1 
ATOM   9345  O O   . TYR B 2 450 ? 187.207 151.624 120.946 1.00 40.29  ? 468  TYR C O   1 
ATOM   9346  C CB  . TYR B 2 450 ? 189.499 153.856 120.466 1.00 54.08  ? 468  TYR C CB  1 
ATOM   9347  C CG  . TYR B 2 450 ? 190.927 154.260 120.170 1.00 54.08  ? 468  TYR C CG  1 
ATOM   9348  C CD1 . TYR B 2 450 ? 191.824 154.506 121.226 1.00 54.08  ? 468  TYR C CD1 1 
ATOM   9349  C CD2 . TYR B 2 450 ? 191.376 154.349 118.840 1.00 54.08  ? 468  TYR C CD2 1 
ATOM   9350  C CE1 . TYR B 2 450 ? 193.180 154.773 120.951 1.00 54.08  ? 468  TYR C CE1 1 
ATOM   9351  C CE2 . TYR B 2 450 ? 192.722 154.638 118.570 1.00 54.08  ? 468  TYR C CE2 1 
ATOM   9352  C CZ  . TYR B 2 450 ? 193.634 154.807 119.621 1.00 54.08  ? 468  TYR C CZ  1 
ATOM   9353  O OH  . TYR B 2 450 ? 194.931 155.065 119.342 1.00 54.08  ? 468  TYR C OH  1 
ATOM   9354  N N   . GLN B 2 451 ? 187.657 152.633 122.894 1.00 40.29  ? 469  GLN C N   1 
ATOM   9355  C CA  . GLN B 2 451 ? 186.340 152.501 123.472 1.00 40.29  ? 469  GLN C CA  1 
ATOM   9356  C C   . GLN B 2 451 ? 185.871 153.698 124.233 1.00 40.29  ? 469  GLN C C   1 
ATOM   9357  O O   . GLN B 2 451 ? 186.488 154.132 125.209 1.00 40.29  ? 469  GLN C O   1 
ATOM   9358  C CB  . GLN B 2 451 ? 186.300 151.294 124.387 1.00 52.28  ? 469  GLN C CB  1 
ATOM   9359  C CG  . GLN B 2 451 ? 185.015 151.124 125.203 1.00 52.28  ? 469  GLN C CG  1 
ATOM   9360  C CD  . GLN B 2 451 ? 183.767 150.866 124.370 1.00 52.28  ? 469  GLN C CD  1 
ATOM   9361  O OE1 . GLN B 2 451 ? 183.675 149.941 123.544 1.00 52.28  ? 469  GLN C OE1 1 
ATOM   9362  N NE2 . GLN B 2 451 ? 182.765 151.710 124.580 1.00 52.28  ? 469  GLN C NE2 1 
ATOM   9363  N N   . LYS B 2 452 ? 184.735 154.221 123.821 1.00 40.29  ? 470  LYS C N   1 
ATOM   9364  C CA  . LYS B 2 452 ? 184.206 155.366 124.509 1.00 40.29  ? 470  LYS C CA  1 
ATOM   9365  C C   . LYS B 2 452 ? 183.980 155.011 125.943 1.00 40.29  ? 470  LYS C C   1 
ATOM   9366  O O   . LYS B 2 452 ? 183.297 154.034 126.246 1.00 40.29  ? 470  LYS C O   1 
ATOM   9367  C CB  . LYS B 2 452 ? 182.922 155.834 123.848 1.00 57.63  ? 470  LYS C CB  1 
ATOM   9368  C CG  . LYS B 2 452 ? 182.347 157.102 124.422 1.00 57.63  ? 470  LYS C CG  1 
ATOM   9369  C CD  . LYS B 2 452 ? 181.130 157.537 123.636 1.00 57.63  ? 470  LYS C CD  1 
ATOM   9370  C CE  . LYS B 2 452 ? 180.529 158.825 124.169 1.00 57.63  ? 470  LYS C CE  1 
ATOM   9371  N NZ  . LYS B 2 452 ? 179.340 159.221 123.374 1.00 57.63  ? 470  LYS C NZ  1 
ATOM   9372  N N   . VAL B 2 453 ? 184.522 155.826 126.829 1.00 40.29  ? 471  VAL C N   1 
ATOM   9373  C CA  . VAL B 2 453 ? 184.352 155.618 128.243 1.00 40.29  ? 471  VAL C CA  1 
ATOM   9374  C C   . VAL B 2 453 ? 183.220 156.551 128.591 1.00 40.29  ? 471  VAL C C   1 
ATOM   9375  O O   . VAL B 2 453 ? 182.364 156.275 129.441 1.00 40.29  ? 471  VAL C O   1 
ATOM   9376  C CB  . VAL B 2 453 ? 185.638 155.906 129.031 1.00 56.74  ? 471  VAL C CB  1 
ATOM   9377  C CG1 . VAL B 2 453 ? 185.378 155.750 130.528 1.00 56.74  ? 471  VAL C CG1 1 
ATOM   9378  C CG2 . VAL B 2 453 ? 186.723 154.936 128.610 1.00 56.74  ? 471  VAL C CG2 1 
ATOM   9379  N N   . GLY B 2 454 ? 183.259 157.701 127.938 1.00 40.29  ? 472  GLY C N   1 
ATOM   9380  C CA  . GLY B 2 454 ? 182.293 158.737 128.147 1.00 40.29  ? 472  GLY C CA  1 
ATOM   9381  C C   . GLY B 2 454 ? 182.554 159.931 127.258 1.00 40.29  ? 472  GLY C C   1 
ATOM   9382  O O   . GLY B 2 454 ? 182.979 159.804 126.104 1.00 40.29  ? 472  GLY C O   1 
ATOM   9383  N N   . TYR B 2 455 ? 182.162 161.085 127.740 1.00 40.29  ? 473  TYR C N   1 
ATOM   9384  C CA  . TYR B 2 455 ? 182.240 162.280 126.926 1.00 40.29  ? 473  TYR C CA  1 
ATOM   9385  C C   . TYR B 2 455 ? 182.399 163.505 127.785 1.00 40.29  ? 473  TYR C C   1 
ATOM   9386  O O   . TYR B 2 455 ? 182.207 163.468 129.008 1.00 40.29  ? 473  TYR C O   1 
ATOM   9387  C CB  . TYR B 2 455 ? 180.982 162.450 126.083 1.00 54.08  ? 473  TYR C CB  1 
ATOM   9388  C CG  . TYR B 2 455 ? 179.804 162.874 126.863 1.00 54.08  ? 473  TYR C CG  1 
ATOM   9389  C CD1 . TYR B 2 455 ? 179.054 161.975 127.567 1.00 54.08  ? 473  TYR C CD1 1 
ATOM   9390  C CD2 . TYR B 2 455 ? 179.485 164.223 126.885 1.00 54.08  ? 473  TYR C CD2 1 
ATOM   9391  C CE1 . TYR B 2 455 ? 177.978 162.428 128.290 1.00 54.08  ? 473  TYR C CE1 1 
ATOM   9392  C CE2 . TYR B 2 455 ? 178.430 164.667 127.600 1.00 54.08  ? 473  TYR C CE2 1 
ATOM   9393  C CZ  . TYR B 2 455 ? 177.672 163.773 128.306 1.00 54.08  ? 473  TYR C CZ  1 
ATOM   9394  O OH  . TYR B 2 455 ? 176.599 164.228 129.027 1.00 54.08  ? 473  TYR C OH  1 
ATOM   9395  N N   . TRP B 2 456 ? 182.777 164.597 127.154 1.00 40.29  ? 474  TRP C N   1 
ATOM   9396  C CA  . TRP B 2 456 ? 182.808 165.893 127.777 1.00 40.29  ? 474  TRP C CA  1 
ATOM   9397  C C   . TRP B 2 456 ? 181.971 166.836 126.955 1.00 40.29  ? 474  TRP C C   1 
ATOM   9398  O O   . TRP B 2 456 ? 181.815 166.676 125.742 1.00 40.29  ? 474  TRP C O   1 
ATOM   9399  C CB  . TRP B 2 456 ? 184.240 166.376 127.937 1.00 51.10  ? 474  TRP C CB  1 
ATOM   9400  C CG  . TRP B 2 456 ? 184.412 167.328 129.063 1.00 51.10  ? 474  TRP C CG  1 
ATOM   9401  C CD1 . TRP B 2 456 ? 184.624 166.926 130.321 1.00 51.10  ? 474  TRP C CD1 1 
ATOM   9402  C CD2 . TRP B 2 456 ? 184.393 168.781 129.120 1.00 51.10  ? 474  TRP C CD2 1 
ATOM   9403  N NE1 . TRP B 2 456 ? 184.697 168.007 131.164 1.00 51.10  ? 474  TRP C NE1 1 
ATOM   9404  C CE2 . TRP B 2 456 ? 184.642 169.175 130.466 1.00 51.10  ? 474  TRP C CE2 1 
ATOM   9405  C CE3 . TRP B 2 456 ? 184.245 169.808 128.178 1.00 51.10  ? 474  TRP C CE3 1 
ATOM   9406  C CZ2 . TRP B 2 456 ? 184.742 170.503 130.862 1.00 51.10  ? 474  TRP C CZ2 1 
ATOM   9407  C CZ3 . TRP B 2 456 ? 184.324 171.157 128.563 1.00 51.10  ? 474  TRP C CZ3 1 
ATOM   9408  C CH2 . TRP B 2 456 ? 184.561 171.504 129.902 1.00 51.10  ? 474  TRP C CH2 1 
ATOM   9409  N N   . ALA B 2 457 ? 181.430 167.823 127.635 1.00 40.29  ? 475  ALA C N   1 
ATOM   9410  C CA  . ALA B 2 457 ? 180.634 168.841 126.995 1.00 40.29  ? 475  ALA C CA  1 
ATOM   9411  C C   . ALA B 2 457 ? 180.919 170.185 127.653 1.00 40.29  ? 475  ALA C C   1 
ATOM   9412  O O   . ALA B 2 457 ? 181.496 171.058 127.015 1.00 40.29  ? 475  ALA C O   1 
ATOM   9413  C CB  . ALA B 2 457 ? 179.177 168.382 127.040 1.00 54.43  ? 475  ALA C CB  1 
ATOM   9414  N N   . GLU B 2 458 ? 180.624 170.333 128.946 1.00 40.29  ? 476  GLU C N   1 
ATOM   9415  C CA  . GLU B 2 458 ? 180.995 171.529 129.673 1.00 40.29  ? 476  GLU C CA  1 
ATOM   9416  C C   . GLU B 2 458 ? 181.483 170.906 130.923 1.00 40.29  ? 476  GLU C C   1 
ATOM   9417  O O   . GLU B 2 458 ? 182.124 171.546 131.749 1.00 40.29  ? 476  GLU C O   1 
ATOM   9418  C CB  . GLU B 2 458 ? 179.811 172.432 129.923 1.00 51.99  ? 476  GLU C CB  1 
ATOM   9419  C CG  . GLU B 2 458 ? 179.093 172.873 128.658 1.00 51.99  ? 476  GLU C CG  1 
ATOM   9420  C CD  . GLU B 2 458 ? 178.315 171.748 128.008 1.00 51.99  ? 476  GLU C CD  1 
ATOM   9421  O OE1 . GLU B 2 458 ? 177.865 170.841 128.736 1.00 51.99  ? 476  GLU C OE1 1 
ATOM   9422  O OE2 . GLU B 2 458 ? 178.153 171.768 126.771 1.00 51.99  ? 476  GLU C OE2 1 
ATOM   9423  N N   . GLY B 2 459 ? 181.159 169.637 131.080 1.00 40.29  ? 477  GLY C N   1 
ATOM   9424  C CA  . GLY B 2 459 ? 181.639 168.890 132.204 1.00 40.29  ? 477  GLY C CA  1 
ATOM   9425  C C   . GLY B 2 459 ? 181.725 167.471 131.703 1.00 40.29  ? 477  GLY C C   1 
ATOM   9426  O O   . GLY B 2 459 ? 181.252 167.191 130.587 1.00 40.29  ? 477  GLY C O   1 
ATOM   9427  N N   . LEU B 2 460 ? 182.302 166.607 132.536 1.00 40.29  ? 478  LEU C N   1 
ATOM   9428  C CA  . LEU B 2 460 ? 182.581 165.191 132.262 1.00 40.29  ? 478  LEU C CA  1 
ATOM   9429  C C   . LEU B 2 460 ? 181.622 164.112 132.760 1.00 40.29  ? 478  LEU C C   1 
ATOM   9430  O O   . LEU B 2 460 ? 181.184 164.134 133.910 1.00 40.29  ? 478  LEU C O   1 
ATOM   9431  C CB  . LEU B 2 460 ? 183.914 164.878 132.960 1.00 57.27  ? 478  LEU C CB  1 
ATOM   9432  C CG  . LEU B 2 460 ? 184.530 163.503 132.785 1.00 57.27  ? 478  LEU C CG  1 
ATOM   9433  C CD1 . LEU B 2 460 ? 185.016 163.310 131.332 1.00 57.27  ? 478  LEU C CD1 1 
ATOM   9434  C CD2 . LEU B 2 460 ? 185.638 163.403 133.735 1.00 57.27  ? 478  LEU C CD2 1 
ATOM   9435  N N   . THR B 2 461 ? 181.394 163.104 131.905 1.00 40.29  ? 479  THR C N   1 
ATOM   9436  C CA  . THR B 2 461 ? 180.688 161.867 132.261 1.00 40.29  ? 479  THR C CA  1 
ATOM   9437  C C   . THR B 2 461 ? 181.529 160.653 131.850 1.00 40.29  ? 479  THR C C   1 
ATOM   9438  O O   . THR B 2 461 ? 181.938 160.586 130.694 1.00 40.29  ? 479  THR C O   1 
ATOM   9439  C CB  . THR B 2 461 ? 179.320 161.779 131.571 1.00 55.15  ? 479  THR C CB  1 
ATOM   9440  O OG1 . THR B 2 461 ? 178.500 162.870 131.989 1.00 55.15  ? 479  THR C OG1 1 
ATOM   9441  C CG2 . THR B 2 461 ? 178.622 160.466 131.894 1.00 55.15  ? 479  THR C CG2 1 
ATOM   9442  N N   . LEU B 2 462 ? 181.765 159.682 132.763 1.00 40.29  ? 480  LEU C N   1 
ATOM   9443  C CA  . LEU B 2 462 ? 182.537 158.460 132.424 1.00 40.29  ? 480  LEU C CA  1 
ATOM   9444  C C   . LEU B 2 462 ? 182.035 157.162 133.073 1.00 40.29  ? 480  LEU C C   1 
ATOM   9445  O O   . LEU B 2 462 ? 181.772 157.128 134.277 1.00 40.29  ? 480  LEU C O   1 
ATOM   9446  C CB  . LEU B 2 462 ? 184.003 158.603 132.860 1.00 57.27  ? 480  LEU C CB  1 
ATOM   9447  C CG  . LEU B 2 462 ? 184.853 159.666 132.187 1.00 57.27  ? 480  LEU C CG  1 
ATOM   9448  C CD1 . LEU B 2 462 ? 186.189 159.760 132.917 1.00 57.27  ? 480  LEU C CD1 1 
ATOM   9449  C CD2 . LEU B 2 462 ? 185.082 159.358 130.745 1.00 57.27  ? 480  LEU C CD2 1 
ATOM   9450  N N   . ASP B 2 463 ? 181.967 156.076 132.284 1.00 40.29  ? 481  ASP C N   1 
ATOM   9451  C CA  . ASP B 2 463 ? 181.640 154.729 132.774 1.00 40.29  ? 481  ASP C CA  1 
ATOM   9452  C C   . ASP B 2 463 ? 182.904 153.937 133.142 1.00 40.29  ? 481  ASP C C   1 
ATOM   9453  O O   . ASP B 2 463 ? 183.604 153.410 132.271 1.00 40.29  ? 481  ASP C O   1 
ATOM   9454  C CB  . ASP B 2 463 ? 180.819 153.961 131.744 1.00 51.30  ? 481  ASP C CB  1 
ATOM   9455  C CG  . ASP B 2 463 ? 180.383 152.573 132.221 1.00 51.30  ? 481  ASP C CG  1 
ATOM   9456  O OD1 . ASP B 2 463 ? 180.949 152.043 133.186 1.00 51.30  ? 481  ASP C OD1 1 
ATOM   9457  O OD2 . ASP B 2 463 ? 179.477 152.042 131.630 1.00 51.30  ? 481  ASP C OD2 1 
ATOM   9458  N N   . THR B 2 464 ? 183.136 153.778 134.442 1.00 42.01  ? 482  THR C N   1 
ATOM   9459  C CA  . THR B 2 464 ? 184.345 153.192 135.012 1.00 42.01  ? 482  THR C CA  1 
ATOM   9460  C C   . THR B 2 464 ? 184.546 151.737 134.612 1.00 42.01  ? 482  THR C C   1 
ATOM   9461  O O   . THR B 2 464 ? 185.654 151.199 134.677 1.00 42.01  ? 482  THR C O   1 
ATOM   9462  C CB  . THR B 2 464 ? 184.293 153.238 136.557 1.00 57.51  ? 482  THR C CB  1 
ATOM   9463  O OG1 . THR B 2 464 ? 184.027 154.574 136.984 1.00 57.51  ? 482  THR C OG1 1 
ATOM   9464  C CG2 . THR B 2 464 ? 185.680 152.827 137.149 1.00 57.51  ? 482  THR C CG2 1 
ATOM   9465  N N   . SER B 2 465 ? 183.474 151.053 134.246 1.00 42.36  ? 483  SER C N   1 
ATOM   9466  C CA  . SER B 2 465 ? 183.574 149.632 133.946 1.00 42.36  ? 483  SER C CA  1 
ATOM   9467  C C   . SER B 2 465 ? 184.362 149.397 132.675 1.00 42.36  ? 483  SER C C   1 
ATOM   9468  O O   . SER B 2 465 ? 184.773 148.276 132.369 1.00 42.36  ? 483  SER C O   1 
ATOM   9469  C CB  . SER B 2 465 ? 182.209 149.004 133.803 1.00 56.42  ? 483  SER C CB  1 
ATOM   9470  O OG  . SER B 2 465 ? 181.572 149.444 132.648 1.00 56.42  ? 483  SER C OG  1 
ATOM   9471  N N   . LEU B 2 466 ? 184.564 150.457 131.914 1.00 40.29  ? 484  LEU C N   1 
ATOM   9472  C CA  . LEU B 2 466 ? 185.267 150.380 130.672 1.00 40.29  ? 484  LEU C CA  1 
ATOM   9473  C C   . LEU B 2 466 ? 186.722 150.750 130.816 1.00 40.29  ? 484  LEU C C   1 
ATOM   9474  O O   . LEU B 2 466 ? 187.421 150.845 129.812 1.00 40.29  ? 484  LEU C O   1 
ATOM   9475  C CB  . LEU B 2 466 ? 184.577 151.297 129.683 1.00 56.70  ? 484  LEU C CB  1 
ATOM   9476  C CG  . LEU B 2 466 ? 183.098 150.951 129.410 1.00 56.70  ? 484  LEU C CG  1 
ATOM   9477  C CD1 . LEU B 2 466 ? 182.529 152.000 128.523 1.00 56.70  ? 484  LEU C CD1 1 
ATOM   9478  C CD2 . LEU B 2 466 ? 182.966 149.566 128.754 1.00 56.70  ? 484  LEU C CD2 1 
ATOM   9479  N N   . ILE B 2 467 ? 187.191 150.981 132.043 1.00 40.59  ? 485  ILE C N   1 
ATOM   9480  C CA  . ILE B 2 467 ? 188.578 151.360 132.226 1.00 40.59  ? 485  ILE C CA  1 
ATOM   9481  C C   . ILE B 2 467 ? 189.438 150.161 132.694 1.00 40.59  ? 485  ILE C C   1 
ATOM   9482  O O   . ILE B 2 467 ? 189.312 149.699 133.830 1.00 40.59  ? 485  ILE C O   1 
ATOM   9483  C CB  . ILE B 2 467 ? 188.680 152.503 133.231 1.00 57.69  ? 485  ILE C CB  1 
ATOM   9484  C CG1 . ILE B 2 467 ? 187.854 153.700 132.718 1.00 57.69  ? 485  ILE C CG1 1 
ATOM   9485  C CG2 . ILE B 2 467 ? 190.130 152.876 133.395 1.00 57.69  ? 485  ILE C CG2 1 
ATOM   9486  C CD1 . ILE B 2 467 ? 187.720 154.839 133.712 1.00 57.69  ? 485  ILE C CD1 1 
ATOM   9487  N N   . PRO B 2 468 ? 190.403 149.691 131.891 1.00 45.52  ? 486  PRO C N   1 
ATOM   9488  C CA  . PRO B 2 468 ? 191.256 148.539 132.148 1.00 45.52  ? 486  PRO C CA  1 
ATOM   9489  C C   . PRO B 2 468 ? 192.109 148.597 133.412 1.00 45.52  ? 486  PRO C C   1 
ATOM   9490  O O   . PRO B 2 468 ? 192.651 147.578 133.823 1.00 45.52  ? 486  PRO C O   1 
ATOM   9491  C CB  . PRO B 2 468 ? 192.182 148.534 130.930 1.00 77.78  ? 486  PRO C CB  1 
ATOM   9492  C CG  . PRO B 2 468 ? 191.424 149.234 129.859 1.00 77.78  ? 486  PRO C CG  1 
ATOM   9493  C CD  . PRO B 2 468 ? 190.615 150.276 130.549 1.00 77.78  ? 486  PRO C CD  1 
ATOM   9494  N N   . TRP B 2 469 ? 192.326 149.782 133.961 1.00 43.81  ? 487  TRP C N   1 
ATOM   9495  C CA  . TRP B 2 469 ? 193.115 149.934 135.173 1.00 43.81  ? 487  TRP C CA  1 
ATOM   9496  C C   . TRP B 2 469 ? 192.300 150.505 136.312 1.00 43.81  ? 487  TRP C C   1 
ATOM   9497  O O   . TRP B 2 469 ? 192.876 151.002 137.278 1.00 43.81  ? 487  TRP C O   1 
ATOM   9498  C CB  . TRP B 2 469 ? 194.287 150.860 134.946 1.00 58.65  ? 487  TRP C CB  1 
ATOM   9499  C CG  . TRP B 2 469 ? 193.858 152.144 134.475 1.00 58.65  ? 487  TRP C CG  1 
ATOM   9500  C CD1 . TRP B 2 469 ? 193.508 153.207 135.215 1.00 58.65  ? 487  TRP C CD1 1 
ATOM   9501  C CD2 . TRP B 2 469 ? 193.679 152.522 133.136 1.00 58.65  ? 487  TRP C CD2 1 
ATOM   9502  N NE1 . TRP B 2 469 ? 193.148 154.229 134.412 1.00 58.65  ? 487  TRP C NE1 1 
ATOM   9503  C CE2 . TRP B 2 469 ? 193.246 153.829 133.144 1.00 58.65  ? 487  TRP C CE2 1 
ATOM   9504  C CE3 . TRP B 2 469 ? 193.838 151.871 131.943 1.00 58.65  ? 487  TRP C CE3 1 
ATOM   9505  C CZ2 . TRP B 2 469 ? 192.976 154.492 132.010 1.00 58.65  ? 487  TRP C CZ2 1 
ATOM   9506  C CZ3 . TRP B 2 469 ? 193.544 152.533 130.801 1.00 58.65  ? 487  TRP C CZ3 1 
ATOM   9507  C CH2 . TRP B 2 469 ? 193.128 153.807 130.829 1.00 58.65  ? 487  TRP C CH2 1 
ATOM   9508  N N   . ALA B 2 470 ? 190.981 150.570 136.164 1.00 49.77  ? 488  ALA C N   1 
ATOM   9509  C CA  . ALA B 2 470 ? 190.193 151.157 137.236 1.00 49.77  ? 488  ALA C CA  1 
ATOM   9510  C C   . ALA B 2 470 ? 188.878 150.427 137.451 1.00 49.77  ? 488  ALA C C   1 
ATOM   9511  O O   . ALA B 2 470 ? 188.281 150.540 138.526 1.00 49.77  ? 488  ALA C O   1 
ATOM   9512  C CB  . ALA B 2 470 ? 189.948 152.620 136.969 1.00 67.24  ? 488  ALA C CB  1 
ATOM   9513  N N   . SER B 2 471 ? 188.403 149.707 136.438 1.00 55.77  ? 489  SER C N   1 
ATOM   9514  C CA  . SER B 2 471 ? 187.173 148.960 136.570 1.00 55.77  ? 489  SER C CA  1 
ATOM   9515  C C   . SER B 2 471 ? 187.482 148.120 137.796 1.00 55.77  ? 489  SER C C   1 
ATOM   9516  O O   . SER B 2 471 ? 188.567 147.567 137.841 1.00 55.77  ? 489  SER C O   1 
ATOM   9517  C CB  . SER B 2 471 ? 186.955 148.118 135.329 1.00 74.28  ? 489  SER C CB  1 
ATOM   9518  O OG  . SER B 2 471 ? 185.816 147.315 135.437 1.00 74.28  ? 489  SER C OG  1 
ATOM   9519  N N   . PRO B 2 472 ? 186.588 147.918 138.771 1.00 64.16  ? 490  PRO C N   1 
ATOM   9520  C CA  . PRO B 2 472 ? 186.890 147.236 140.030 1.00 64.16  ? 490  PRO C CA  1 
ATOM   9521  C C   . PRO B 2 472 ? 187.687 145.933 139.951 1.00 64.16  ? 490  PRO C C   1 
ATOM   9522  O O   . PRO B 2 472 ? 188.582 145.719 140.771 1.00 64.16  ? 490  PRO C O   1 
ATOM   9523  C CB  . PRO B 2 472 ? 185.477 146.955 140.553 1.00 109.64 ? 490  PRO C CB  1 
ATOM   9524  C CG  . PRO B 2 472 ? 184.651 148.109 140.022 1.00 109.64 ? 490  PRO C CG  1 
ATOM   9525  C CD  . PRO B 2 472 ? 185.197 148.378 138.634 1.00 109.64 ? 490  PRO C CD  1 
ATOM   9526  N N   . SER B 2 473 ? 187.451 145.095 138.945 1.00 63.92  ? 491  SER C N   1 
ATOM   9527  C CA  . SER B 2 473 ? 188.172 143.829 138.841 1.00 63.92  ? 491  SER C CA  1 
ATOM   9528  C C   . SER B 2 473 ? 189.623 144.019 138.431 1.00 63.92  ? 491  SER C C   1 
ATOM   9529  O O   . SER B 2 473 ? 190.449 143.110 138.546 1.00 63.92  ? 491  SER C O   1 
ATOM   9530  C CB  . SER B 2 473 ? 187.475 142.930 137.850 1.00 85.68  ? 491  SER C CB  1 
ATOM   9531  O OG  . SER B 2 473 ? 187.553 143.460 136.561 1.00 85.68  ? 491  SER C OG  1 
ATOM   9532  N N   . ALA B 2 474 ? 189.923 145.204 137.925 1.00 65.28  ? 492  ALA C N   1 
ATOM   9533  C CA  . ALA B 2 474 ? 191.235 145.595 137.463 1.00 65.28  ? 492  ALA C CA  1 
ATOM   9534  C C   . ALA B 2 474 ? 192.072 146.159 138.598 1.00 65.28  ? 492  ALA C C   1 
ATOM   9535  O O   . ALA B 2 474 ? 193.266 146.416 138.429 1.00 65.28  ? 492  ALA C O   1 
ATOM   9536  C CB  . ALA B 2 474 ? 191.123 146.644 136.368 1.00 88.19  ? 492  ALA C CB  1 
ATOM   9537  N N   . GLY B 2 475 ? 191.454 146.386 139.751 1.00 63.39  ? 493  GLY C N   1 
ATOM   9538  C CA  . GLY B 2 475 ? 192.166 147.018 140.830 1.00 63.39  ? 493  GLY C CA  1 
ATOM   9539  C C   . GLY B 2 475 ? 192.101 148.538 140.658 1.00 63.39  ? 493  GLY C C   1 
ATOM   9540  O O   . GLY B 2 475 ? 191.422 149.048 139.772 1.00 63.39  ? 493  GLY C O   1 
ATOM   9541  N N   . PRO B 2 476 ? 192.718 149.291 141.565 1.00 57.25  ? 494  PRO C N   1 
ATOM   9542  C CA  . PRO B 2 476 ? 192.776 150.740 141.602 1.00 57.25  ? 494  PRO C CA  1 
ATOM   9543  C C   . PRO B 2 476 ? 193.754 151.334 140.598 1.00 57.25  ? 494  PRO C C   1 
ATOM   9544  O O   . PRO B 2 476 ? 194.678 150.661 140.146 1.00 57.25  ? 494  PRO C O   1 
ATOM   9545  C CB  . PRO B 2 476 ? 193.251 151.003 143.028 1.00 97.83  ? 494  PRO C CB  1 
ATOM   9546  C CG  . PRO B 2 476 ? 194.110 149.809 143.355 1.00 97.83  ? 494  PRO C CG  1 
ATOM   9547  C CD  . PRO B 2 476 ? 193.443 148.637 142.667 1.00 97.83  ? 494  PRO C CD  1 
ATOM   9548  N N   . LEU B 2 477 ? 193.599 152.625 140.360 1.00 45.55  ? 495  LEU C N   1 
ATOM   9549  C CA  . LEU B 2 477 ? 194.535 153.424 139.588 1.00 45.55  ? 495  LEU C CA  1 
ATOM   9550  C C   . LEU B 2 477 ? 195.881 153.439 140.346 1.00 45.55  ? 495  LEU C C   1 
ATOM   9551  O O   . LEU B 2 477 ? 195.860 153.403 141.579 1.00 45.55  ? 495  LEU C O   1 
ATOM   9552  C CB  . LEU B 2 477 ? 194.014 154.879 139.519 1.00 64.74  ? 495  LEU C CB  1 
ATOM   9553  C CG  . LEU B 2 477 ? 194.818 155.950 138.682 1.00 64.74  ? 495  LEU C CG  1 
ATOM   9554  C CD1 . LEU B 2 477 ? 194.698 155.730 137.181 1.00 64.74  ? 495  LEU C CD1 1 
ATOM   9555  C CD2 . LEU B 2 477 ? 194.337 157.292 139.033 1.00 64.74  ? 495  LEU C CD2 1 
ATOM   9556  N N   . PRO B 2 478 ? 197.050 153.456 139.663 1.00 41.40  ? 496  PRO C N   1 
ATOM   9557  C CA  . PRO B 2 478 ? 198.376 153.617 140.234 1.00 41.40  ? 496  PRO C CA  1 
ATOM   9558  C C   . PRO B 2 478 ? 198.403 154.920 140.998 1.00 41.40  ? 496  PRO C C   1 
ATOM   9559  O O   . PRO B 2 478 ? 197.560 155.778 140.767 1.00 41.40  ? 496  PRO C O   1 
ATOM   9560  C CB  . PRO B 2 478 ? 199.294 153.620 139.015 1.00 70.74  ? 496  PRO C CB  1 
ATOM   9561  C CG  . PRO B 2 478 ? 198.539 152.851 137.982 1.00 70.74  ? 496  PRO C CG  1 
ATOM   9562  C CD  . PRO B 2 478 ? 197.095 153.198 138.210 1.00 70.74  ? 496  PRO C CD  1 
ATOM   9563  N N   . ALA B 2 479 ? 199.345 155.069 141.921 1.00 40.29  ? 497  ALA C N   1 
ATOM   9564  C CA  . ALA B 2 479 ? 199.322 156.242 142.770 1.00 40.29  ? 497  ALA C CA  1 
ATOM   9565  C C   . ALA B 2 479 ? 199.112 157.506 141.982 1.00 40.29  ? 497  ALA C C   1 
ATOM   9566  O O   . ALA B 2 479 ? 199.786 157.796 140.995 1.00 40.29  ? 497  ALA C O   1 
ATOM   9567  C CB  . ALA B 2 479 ? 200.627 156.350 143.538 1.00 54.43  ? 497  ALA C CB  1 
ATOM   9568  N N   . SER B 2 480 ? 198.144 158.269 142.465 1.00 43.96  ? 498  SER C N   1 
ATOM   9569  C CA  . SER B 2 480 ? 197.722 159.519 141.879 1.00 43.96  ? 498  SER C CA  1 
ATOM   9570  C C   . SER B 2 480 ? 197.472 160.514 142.987 1.00 43.96  ? 498  SER C C   1 
ATOM   9571  O O   . SER B 2 480 ? 197.035 161.659 142.779 1.00 43.96  ? 498  SER C O   1 
ATOM   9572  C CB  . SER B 2 480 ? 196.456 159.263 141.163 1.00 58.55  ? 498  SER C CB  1 
ATOM   9573  O OG  . SER B 2 480 ? 195.479 158.882 142.085 1.00 58.55  ? 498  SER C OG  1 
ATOM   9574  N N   . ARG B 2 481 ? 197.789 160.155 144.238 1.00 56.30  ? 499  ARG C N   1 
ATOM   9575  C CA  . ARG B 2 481 ? 197.528 160.920 145.456 1.00 56.30  ? 499  ARG C CA  1 
ATOM   9576  C C   . ARG B 2 481 ? 198.751 160.906 146.359 1.00 56.30  ? 499  ARG C C   1 
ATOM   9577  O O   . ARG B 2 481 ? 199.626 160.055 146.214 1.00 56.30  ? 499  ARG C O   1 
ATOM   9578  C CB  . ARG B 2 481 ? 196.335 160.314 146.210 1.00 79.07  ? 499  ARG C CB  1 
ATOM   9579  C CG  . ARG B 2 481 ? 195.027 160.333 145.411 1.00 79.07  ? 499  ARG C CG  1 
ATOM   9580  C CD  . ARG B 2 481 ? 193.839 159.898 146.277 1.00 79.07  ? 499  ARG C CD  1 
ATOM   9581  N NE  . ARG B 2 481 ? 193.483 160.901 147.302 1.00 79.07  ? 499  ARG C NE  1 
ATOM   9582  C CZ  . ARG B 2 481 ? 192.610 161.878 147.194 1.00 79.07  ? 499  ARG C CZ  1 
ATOM   9583  N NH1 . ARG B 2 481 ? 192.323 162.608 148.223 1.00 79.07  ? 499  ARG C NH1 1 
ATOM   9584  N NH2 . ARG B 2 481 ? 192.005 162.151 146.079 1.00 79.07  ? 499  ARG C NH2 1 
ATOM   9585  N N   . CYS B 2 482 ? 198.762 161.808 147.326 1.00 70.77  ? 500  CYS C N   1 
ATOM   9586  C CA  . CYS B 2 482 ? 199.738 161.816 148.404 1.00 70.77  ? 500  CYS C CA  1 
ATOM   9587  C C   . CYS B 2 482 ? 199.064 161.946 149.770 1.00 70.77  ? 500  CYS C C   1 
ATOM   9588  O O   . CYS B 2 482 ? 199.096 161.015 150.572 1.00 70.77  ? 500  CYS C O   1 
ATOM   9589  C CB  . CYS B 2 482 ? 200.721 162.963 148.185 1.00 91.71  ? 500  CYS C CB  1 
ATOM   9590  S SG  . CYS B 2 482 ? 202.013 162.711 146.954 1.00 91.71  ? 500  CYS C SG  1 
ATOM   9591  N N   . SER B 2 483 ? 198.464 163.103 150.039 1.00 75.44  ? 501  SER C N   1 
ATOM   9592  C CA  . SER B 2 483 ? 197.941 163.446 151.357 1.00 75.44  ? 501  SER C CA  1 
ATOM   9593  C C   . SER B 2 483 ? 196.732 164.367 151.277 1.00 75.44  ? 501  SER C C   1 
ATOM   9594  O O   . SER B 2 483 ? 196.518 165.089 150.306 1.00 75.44  ? 501  SER C O   1 
ATOM   9595  C CB  . SER B 2 483 ? 199.041 164.078 152.207 1.00 100.48 ? 501  SER C CB  1 
ATOM   9596  O OG  . SER B 2 483 ? 199.511 165.287 151.645 1.00 100.48 ? 501  SER C OG  1 
ATOM   9597  N N   . GLU B 2 484 ? 195.912 164.308 152.316 1.00 72.15  ? 502  GLU C N   1 
ATOM   9598  C CA  . GLU B 2 484 ? 194.628 164.999 152.408 1.00 72.15  ? 502  GLU C CA  1 
ATOM   9599  C C   . GLU B 2 484 ? 194.775 166.479 152.782 1.00 72.15  ? 502  GLU C C   1 
ATOM   9600  O O   . GLU B 2 484 ? 195.846 166.901 153.225 1.00 72.15  ? 502  GLU C O   1 
ATOM   9601  C CB  . GLU B 2 484 ? 193.787 164.244 153.451 1.00 95.09  ? 502  GLU C CB  1 
ATOM   9602  C CG  . GLU B 2 484 ? 193.465 162.811 153.003 1.00 95.09  ? 502  GLU C CG  1 
ATOM   9603  C CD  . GLU B 2 484 ? 192.872 162.761 151.585 1.00 95.09  ? 502  GLU C CD  1 
ATOM   9604  O OE1 . GLU B 2 484 ? 191.853 163.441 151.337 1.00 95.09  ? 502  GLU C OE1 1 
ATOM   9605  O OE2 . GLU B 2 484 ? 193.424 162.066 150.705 1.00 95.09  ? 502  GLU C OE2 1 
ATOM   9606  N N   . PRO B 2 485 ? 193.696 167.277 152.682 1.00 71.76  ? 503  PRO C N   1 
ATOM   9607  C CA  . PRO B 2 485 ? 193.593 168.590 153.313 1.00 71.76  ? 503  PRO C CA  1 
ATOM   9608  C C   . PRO B 2 485 ? 193.505 168.468 154.849 1.00 71.76  ? 503  PRO C C   1 
ATOM   9609  O O   . PRO B 2 485 ? 192.509 168.820 155.480 1.00 71.76  ? 503  PRO C O   1 
ATOM   9610  C CB  . PRO B 2 485 ? 192.380 169.259 152.658 1.00 122.62 ? 503  PRO C CB  1 
ATOM   9611  C CG  . PRO B 2 485 ? 191.482 168.080 152.318 1.00 122.62 ? 503  PRO C CG  1 
ATOM   9612  C CD  . PRO B 2 485 ? 192.481 166.997 151.928 1.00 122.62 ? 503  PRO C CD  1 
ATOM   9613  N N   . CYS B 2 486 ? 194.580 167.974 155.458 1.00 75.14  ? 504  CYS C N   1 
ATOM   9614  C CA  . CYS B 2 486 ? 194.842 168.008 156.896 1.00 75.14  ? 504  CYS C CA  1 
ATOM   9615  C C   . CYS B 2 486 ? 195.169 169.458 157.317 1.00 75.14  ? 504  CYS C C   1 
ATOM   9616  O O   . CYS B 2 486 ? 196.304 169.907 157.174 1.00 75.14  ? 504  CYS C O   1 
ATOM   9617  C CB  . CYS B 2 486 ? 195.974 167.005 157.153 1.00 97.37  ? 504  CYS C CB  1 
ATOM   9618  S SG  . CYS B 2 486 ? 196.688 166.999 158.810 1.00 97.37  ? 504  CYS C SG  1 
ATOM   9619  N N   . LEU B 2 487 ? 194.145 170.212 157.741 1.00 75.89  ? 505  LEU C N   1 
ATOM   9620  C CA  . LEU B 2 487 ? 194.146 171.683 157.910 1.00 75.89  ? 505  LEU C CA  1 
ATOM   9621  C C   . LEU B 2 487 ? 193.435 172.119 159.211 1.00 75.89  ? 505  LEU C C   1 
ATOM   9622  O O   . LEU B 2 487 ? 192.675 173.088 159.244 1.00 75.89  ? 505  LEU C O   1 
ATOM   9623  C CB  . LEU B 2 487 ? 193.493 172.343 156.674 1.00 107.87 ? 505  LEU C CB  1 
ATOM   9624  C CG  . LEU B 2 487 ? 194.160 172.063 155.319 1.00 107.87 ? 505  LEU C CG  1 
ATOM   9625  C CD1 . LEU B 2 487 ? 193.294 172.594 154.183 1.00 107.87 ? 505  LEU C CD1 1 
ATOM   9626  C CD2 . LEU B 2 487 ? 195.523 172.726 155.206 1.00 107.87 ? 505  LEU C CD2 1 
ATOM   9627  N N   . GLN B 2 488 ? 193.597 171.331 160.264 1.00 75.45  ? 506  GLN C N   1 
ATOM   9628  C CA  . GLN B 2 488 ? 192.712 171.283 161.424 1.00 75.45  ? 506  GLN C CA  1 
ATOM   9629  C C   . GLN B 2 488 ? 193.518 170.935 162.685 1.00 75.45  ? 506  GLN C C   1 
ATOM   9630  O O   . GLN B 2 488 ? 194.640 171.397 162.842 1.00 75.45  ? 506  GLN C O   1 
ATOM   9631  C CB  . GLN B 2 488 ? 191.527 170.346 161.088 1.00 105.16 ? 506  GLN C CB  1 
ATOM   9632  C CG  . GLN B 2 488 ? 191.862 168.937 160.544 1.00 105.16 ? 506  GLN C CG  1 
ATOM   9633  C CD  . GLN B 2 488 ? 192.081 167.865 161.604 1.00 105.16 ? 506  GLN C CD  1 
ATOM   9634  O OE1 . GLN B 2 488 ? 191.497 167.868 162.676 1.00 105.16 ? 506  GLN C OE1 1 
ATOM   9635  N NE2 . GLN B 2 488 ? 192.934 166.900 161.352 1.00 105.16 ? 506  GLN C NE2 1 
ATOM   9636  N N   . ASN B 2 489 ? 192.969 170.155 163.613 1.00 81.85  ? 507  ASN C N   1 
ATOM   9637  C CA  . ASN B 2 489 ? 193.663 169.727 164.834 1.00 81.85  ? 507  ASN C CA  1 
ATOM   9638  C C   . ASN B 2 489 ? 194.990 169.007 164.527 1.00 81.85  ? 507  ASN C C   1 
ATOM   9639  O O   . ASN B 2 489 ? 195.977 169.157 165.244 1.00 81.85  ? 507  ASN C O   1 
ATOM   9640  C CB  . ASN B 2 489 ? 192.718 168.834 165.652 1.00 108.88 ? 507  ASN C CB  1 
ATOM   9641  C CG  . ASN B 2 489 ? 191.330 169.428 165.821 1.00 108.88 ? 507  ASN C CG  1 
ATOM   9642  O OD1 . ASN B 2 489 ? 191.082 170.277 166.661 1.00 108.88 ? 507  ASN C OD1 1 
ATOM   9643  N ND2 . ASN B 2 489 ? 190.383 169.013 165.016 1.00 108.88 ? 507  ASN C ND2 1 
ATOM   9644  N N   . GLU B 2 490 ? 195.031 168.276 163.414 1.00 86.21  ? 508  GLU C N   1 
ATOM   9645  C CA  . GLU B 2 490 ? 196.264 168.060 162.671 1.00 86.21  ? 508  GLU C CA  1 
ATOM   9646  C C   . GLU B 2 490 ? 196.331 169.003 161.481 1.00 86.21  ? 508  GLU C C   1 
ATOM   9647  O O   . GLU B 2 490 ? 195.338 169.256 160.802 1.00 86.21  ? 508  GLU C O   1 
ATOM   9648  C CB  . GLU B 2 490 ? 196.415 166.632 162.162 1.00 113.62 ? 508  GLU C CB  1 
ATOM   9649  C CG  . GLU B 2 490 ? 196.353 165.555 163.235 1.00 113.62 ? 508  GLU C CG  1 
ATOM   9650  C CD  . GLU B 2 490 ? 196.857 164.228 162.671 1.00 113.62 ? 508  GLU C CD  1 
ATOM   9651  O OE1 . GLU B 2 490 ? 198.053 164.114 162.341 1.00 113.62 ? 508  GLU C OE1 1 
ATOM   9652  O OE2 . GLU B 2 490 ? 196.043 163.285 162.555 1.00 113.62 ? 508  GLU C OE2 1 
ATOM   9653  N N   . VAL B 2 491 ? 197.542 169.452 161.202 1.00 79.06  ? 509  VAL C N   1 
ATOM   9654  C CA  . VAL B 2 491 ? 197.943 170.376 160.145 1.00 79.06  ? 509  VAL C CA  1 
ATOM   9655  C C   . VAL B 2 491 ? 199.076 169.747 159.341 1.00 79.06  ? 509  VAL C C   1 
ATOM   9656  O O   . VAL B 2 491 ? 199.727 168.811 159.802 1.00 79.06  ? 509  VAL C O   1 
ATOM   9657  C CB  . VAL B 2 491 ? 198.403 171.710 160.742 1.00 111.33 ? 509  VAL C CB  1 
ATOM   9658  C CG1 . VAL B 2 491 ? 197.220 172.534 161.225 1.00 111.33 ? 509  VAL C CG1 1 
ATOM   9659  C CG2 . VAL B 2 491 ? 199.400 171.524 161.890 1.00 111.33 ? 509  VAL C CG2 1 
ATOM   9660  N N   . LYS B 2 492 ? 199.309 170.199 158.112 1.00 73.68  ? 510  LYS C N   1 
ATOM   9661  C CA  . LYS B 2 492 ? 200.340 169.610 157.262 1.00 73.68  ? 510  LYS C CA  1 
ATOM   9662  C C   . LYS B 2 492 ? 201.759 169.752 157.848 1.00 73.68  ? 510  LYS C C   1 
ATOM   9663  O O   . LYS B 2 492 ? 202.015 170.611 158.685 1.00 73.68  ? 510  LYS C O   1 
ATOM   9664  C CB  . LYS B 2 492 ? 200.213 170.170 155.838 1.00 105.39 ? 510  LYS C CB  1 
ATOM   9665  C CG  . LYS B 2 492 ? 199.338 169.245 154.983 1.00 105.39 ? 510  LYS C CG  1 
ATOM   9666  C CD  . LYS B 2 492 ? 199.099 169.800 153.572 1.00 105.39 ? 510  LYS C CD  1 
ATOM   9667  C CE  . LYS B 2 492 ? 198.763 168.656 152.610 1.00 105.39 ? 510  LYS C CE  1 
ATOM   9668  N NZ  . LYS B 2 492 ? 198.562 169.155 151.229 1.00 105.39 ? 510  LYS C NZ  1 
ATOM   9669  N N   . SER B 2 493 ? 202.698 168.906 157.424 1.00 68.72  ? 511  SER C N   1 
ATOM   9670  C CA  . SER B 2 493 ? 204.130 169.142 157.642 1.00 68.72  ? 511  SER C CA  1 
ATOM   9671  C C   . SER B 2 493 ? 204.633 170.260 156.729 1.00 68.72  ? 511  SER C C   1 
ATOM   9672  O O   . SER B 2 493 ? 203.854 170.863 156.004 1.00 68.72  ? 511  SER C O   1 
ATOM   9673  C CB  . SER B 2 493 ? 204.929 167.847 157.461 1.00 91.53  ? 511  SER C CB  1 
ATOM   9674  O OG  . SER B 2 493 ? 205.162 167.496 156.107 1.00 91.53  ? 511  SER C OG  1 
ATOM   9675  N N   . VAL B 2 494 ? 205.937 170.539 156.746 1.00 76.35  ? 512  VAL C N   1 
ATOM   9676  C CA  . VAL B 2 494 ? 206.591 171.456 155.792 1.00 76.35  ? 512  VAL C CA  1 
ATOM   9677  C C   . VAL B 2 494 ? 207.719 170.773 155.007 1.00 76.35  ? 512  VAL C C   1 
ATOM   9678  O O   . VAL B 2 494 ? 208.723 171.392 154.664 1.00 76.35  ? 512  VAL C O   1 
ATOM   9679  C CB  . VAL B 2 494 ? 206.989 172.806 156.415 1.00 110.66 ? 512  VAL C CB  1 
ATOM   9680  C CG1 . VAL B 2 494 ? 205.761 173.557 156.915 1.00 110.66 ? 512  VAL C CG1 1 
ATOM   9681  C CG2 . VAL B 2 494 ? 207.986 172.679 157.565 1.00 110.66 ? 512  VAL C CG2 1 
ATOM   9682  N N   . GLN B 2 495 ? 207.562 169.475 154.727 1.00 81.19  ? 513  GLN C N   1 
ATOM   9683  C CA  . GLN B 2 495 ? 208.518 168.659 153.966 1.00 81.19  ? 513  GLN C CA  1 
ATOM   9684  C C   . GLN B 2 495 ? 208.990 169.393 152.688 1.00 81.19  ? 513  GLN C C   1 
ATOM   9685  O O   . GLN B 2 495 ? 208.157 169.688 151.830 1.00 81.19  ? 513  GLN C O   1 
ATOM   9686  C CB  . GLN B 2 495 ? 207.852 167.299 153.653 1.00 113.16 ? 513  GLN C CB  1 
ATOM   9687  C CG  . GLN B 2 495 ? 208.515 166.474 152.534 1.00 113.16 ? 513  GLN C CG  1 
ATOM   9688  C CD  . GLN B 2 495 ? 209.952 166.063 152.846 1.00 113.16 ? 513  GLN C CD  1 
ATOM   9689  O OE1 . GLN B 2 495 ? 210.255 165.559 153.914 1.00 113.16 ? 513  GLN C OE1 1 
ATOM   9690  N NE2 . GLN B 2 495 ? 210.891 166.245 151.946 1.00 113.16 ? 513  GLN C NE2 1 
ATOM   9691  N N   . PRO B 2 496 ? 210.290 169.694 152.516 1.00 81.31  ? 514  PRO C N   1 
ATOM   9692  C CA  . PRO B 2 496 ? 210.754 170.333 151.301 1.00 81.31  ? 514  PRO C CA  1 
ATOM   9693  C C   . PRO B 2 496 ? 210.395 169.523 150.071 1.00 81.31  ? 514  PRO C C   1 
ATOM   9694  O O   . PRO B 2 496 ? 210.370 168.290 150.109 1.00 81.31  ? 514  PRO C O   1 
ATOM   9695  C CB  . PRO B 2 496 ? 212.272 170.375 151.500 1.00 165.95 ? 514  PRO C CB  1 
ATOM   9696  C CG  . PRO B 2 496 ? 212.458 170.372 152.997 1.00 165.95 ? 514  PRO C CG  1 
ATOM   9697  C CD  . PRO B 2 496 ? 211.337 169.522 153.541 1.00 165.95 ? 514  PRO C CD  1 
ATOM   9698  N N   . GLY B 2 497 ? 210.086 170.206 148.974 1.00 80.42  ? 515  GLY C N   1 
ATOM   9699  C CA  . GLY B 2 497 ? 209.786 169.540 147.707 1.00 80.42  ? 515  GLY C CA  1 
ATOM   9700  C C   . GLY B 2 497 ? 208.347 169.049 147.631 1.00 80.42  ? 515  GLY C C   1 
ATOM   9701  O O   . GLY B 2 497 ? 207.533 169.532 146.837 1.00 80.42  ? 515  GLY C O   1 
ATOM   9702  N N   . GLU B 2 498 ? 207.992 168.058 148.433 1.00 88.12  ? 516  GLU C N   1 
ATOM   9703  C CA  . GLU B 2 498 ? 206.670 167.430 148.407 1.00 88.12  ? 516  GLU C CA  1 
ATOM   9704  C C   . GLU B 2 498 ? 205.571 168.300 149.066 1.00 88.12  ? 516  GLU C C   1 
ATOM   9705  O O   . GLU B 2 498 ? 204.826 167.829 149.917 1.00 88.12  ? 516  GLU C O   1 
ATOM   9706  C CB  . GLU B 2 498 ? 206.802 165.994 148.971 1.00 118.26 ? 516  GLU C CB  1 
ATOM   9707  C CG  . GLU B 2 498 ? 206.794 164.967 147.826 1.00 118.26 ? 516  GLU C CG  1 
ATOM   9708  C CD  . GLU B 2 498 ? 206.486 163.544 148.315 1.00 118.26 ? 516  GLU C CD  1 
ATOM   9709  O OE1 . GLU B 2 498 ? 207.084 163.098 149.318 1.00 118.26 ? 516  GLU C OE1 1 
ATOM   9710  O OE2 . GLU B 2 498 ? 205.655 162.865 147.677 1.00 118.26 ? 516  GLU C OE2 1 
ATOM   9711  N N   . VAL B 2 499 ? 205.409 169.564 148.644 1.00 96.33  ? 517  VAL C N   1 
ATOM   9712  C CA  . VAL B 2 499 ? 204.410 170.482 149.205 1.00 96.33  ? 517  VAL C CA  1 
ATOM   9713  C C   . VAL B 2 499 ? 202.985 169.957 149.036 1.00 96.33  ? 517  VAL C C   1 
ATOM   9714  O O   . VAL B 2 499 ? 202.211 169.874 149.994 1.00 96.33  ? 517  VAL C O   1 
ATOM   9715  C CB  . VAL B 2 499 ? 204.565 171.887 148.598 1.00 139.62 ? 517  VAL C CB  1 
ATOM   9716  C CG1 . VAL B 2 499 ? 203.425 172.797 149.067 1.00 139.62 ? 517  VAL C CG1 1 
ATOM   9717  C CG2 . VAL B 2 499 ? 205.919 172.437 149.017 1.00 139.62 ? 517  VAL C CG2 1 
ATOM   9718  N N   . CYS B 2 500 ? 202.681 169.470 147.822 1.00 101.33 ? 518  CYS C N   1 
ATOM   9719  C CA  . CYS B 2 500 ? 201.402 168.935 147.401 1.00 101.33 ? 518  CYS C CA  1 
ATOM   9720  C C   . CYS B 2 500 ? 201.242 167.545 147.985 1.00 101.33 ? 518  CYS C C   1 
ATOM   9721  O O   . CYS B 2 500 ? 200.178 166.933 147.885 1.00 101.33 ? 518  CYS C O   1 
ATOM   9722  C CB  . CYS B 2 500 ? 201.364 168.833 145.865 1.00 131.31 ? 518  CYS C CB  1 
ATOM   9723  S SG  . CYS B 2 500 ? 201.491 170.402 144.991 1.00 131.31 ? 518  CYS C SG  1 
ATOM   9724  N N   . CYS B 2 501 ? 202.254 167.045 148.698 1.00 100.81 ? 519  CYS C N   1 
ATOM   9725  C CA  . CYS B 2 501 ? 202.309 165.757 149.362 1.00 100.81 ? 519  CYS C CA  1 
ATOM   9726  C C   . CYS B 2 501 ? 202.702 165.889 150.844 1.00 100.81 ? 519  CYS C C   1 
ATOM   9727  O O   . CYS B 2 501 ? 203.134 164.904 151.444 1.00 100.81 ? 519  CYS C O   1 
ATOM   9728  C CB  . CYS B 2 501 ? 203.291 164.895 148.569 1.00 130.63 ? 519  CYS C CB  1 
ATOM   9729  S SG  . CYS B 2 501 ? 202.812 164.572 146.860 1.00 130.63 ? 519  CYS C SG  1 
ATOM   9730  N N   . TRP B 2 502 ? 202.575 167.076 151.455 1.00 89.23  ? 520  TRP C N   1 
ATOM   9731  C CA  . TRP B 2 502 ? 202.952 167.279 152.854 1.00 89.23  ? 520  TRP C CA  1 
ATOM   9732  C C   . TRP B 2 502 ? 202.226 166.301 153.769 1.00 89.23  ? 520  TRP C C   1 
ATOM   9733  O O   . TRP B 2 502 ? 201.037 166.032 153.597 1.00 89.23  ? 520  TRP C O   1 
ATOM   9734  C CB  . TRP B 2 502 ? 202.683 168.721 153.302 1.00 119.46 ? 520  TRP C CB  1 
ATOM   9735  C CG  . TRP B 2 502 ? 203.719 169.745 152.978 1.00 119.46 ? 520  TRP C CG  1 
ATOM   9736  C CD1 . TRP B 2 502 ? 204.956 169.481 152.515 1.00 119.46 ? 520  TRP C CD1 1 
ATOM   9737  C CD2 . TRP B 2 502 ? 203.670 171.202 153.146 1.00 119.46 ? 520  TRP C CD2 1 
ATOM   9738  N NE1 . TRP B 2 502 ? 205.670 170.648 152.405 1.00 119.46 ? 520  TRP C NE1 1 
ATOM   9739  C CE2 . TRP B 2 502 ? 204.930 171.745 152.759 1.00 119.46 ? 520  TRP C CE2 1 
ATOM   9740  C CE3 . TRP B 2 502 ? 202.712 172.130 153.604 1.00 119.46 ? 520  TRP C CE3 1 
ATOM   9741  C CZ2 . TRP B 2 502 ? 205.234 173.108 152.825 1.00 119.46 ? 520  TRP C CZ2 1 
ATOM   9742  C CZ3 . TRP B 2 502 ? 203.015 173.502 153.704 1.00 119.46 ? 520  TRP C CZ3 1 
ATOM   9743  C CH2 . TRP B 2 502 ? 204.267 173.997 153.311 1.00 119.46 ? 520  TRP C CH2 1 
ATOM   9744  N N   . LEU B 2 503 ? 202.961 165.784 154.747 1.00 80.38  ? 521  LEU C N   1 
ATOM   9745  C CA  . LEU B 2 503 ? 202.480 164.818 155.732 1.00 80.38  ? 521  LEU C CA  1 
ATOM   9746  C C   . LEU B 2 503 ? 201.400 165.463 156.617 1.00 80.38  ? 521  LEU C C   1 
ATOM   9747  O O   . LEU B 2 503 ? 201.284 166.680 156.631 1.00 80.38  ? 521  LEU C O   1 
ATOM   9748  C CB  . LEU B 2 503 ? 203.673 164.312 156.572 1.00 114.25 ? 521  LEU C CB  1 
ATOM   9749  C CG  . LEU B 2 503 ? 204.970 164.004 155.791 1.00 114.25 ? 521  LEU C CG  1 
ATOM   9750  C CD1 . LEU B 2 503 ? 206.069 163.553 156.746 1.00 114.25 ? 521  LEU C CD1 1 
ATOM   9751  C CD2 . LEU B 2 503 ? 204.761 162.925 154.737 1.00 114.25 ? 521  LEU C CD2 1 
ATOM   9752  N N   . CYS B 2 504 ? 200.644 164.693 157.395 1.00 83.89  ? 522  CYS C N   1 
ATOM   9753  C CA  . CYS B 2 504 ? 199.682 165.235 158.365 1.00 83.89  ? 522  CYS C CA  1 
ATOM   9754  C C   . CYS B 2 504 ? 200.228 165.098 159.796 1.00 83.89  ? 522  CYS C C   1 
ATOM   9755  O O   . CYS B 2 504 ? 200.714 164.023 160.157 1.00 83.89  ? 522  CYS C O   1 
ATOM   9756  C CB  . CYS B 2 504 ? 198.349 164.520 158.153 1.00 108.71 ? 522  CYS C CB  1 
ATOM   9757  S SG  . CYS B 2 504 ? 196.991 165.036 159.232 1.00 108.71 ? 522  CYS C SG  1 
ATOM   9758  N N   . ILE B 2 505 ? 200.233 166.191 160.571 1.00 77.92  ? 523  ILE C N   1 
ATOM   9759  C CA  . ILE B 2 505 ? 200.912 166.303 161.869 1.00 77.92  ? 523  ILE C CA  1 
ATOM   9760  C C   . ILE B 2 505 ? 200.023 167.033 162.901 1.00 77.92  ? 523  ILE C C   1 
ATOM   9761  O O   . ILE B 2 505 ? 199.564 168.142 162.638 1.00 77.92  ? 523  ILE C O   1 
ATOM   9762  C CB  . ILE B 2 505 ? 202.284 166.999 161.683 1.00 114.84 ? 523  ILE C CB  1 
ATOM   9763  C CG1 . ILE B 2 505 ? 203.197 166.114 160.796 1.00 114.84 ? 523  ILE C CG1 1 
ATOM   9764  C CG2 . ILE B 2 505 ? 202.948 167.279 163.039 1.00 114.84 ? 523  ILE C CG2 1 
ATOM   9765  C CD1 . ILE B 2 505 ? 204.655 166.562 160.675 1.00 114.84 ? 523  ILE C CD1 1 
ATOM   9766  N N   . PRO B 2 506 ? 199.814 166.498 164.117 1.00 82.27  ? 524  PRO C N   1 
ATOM   9767  C CA  . PRO B 2 506 ? 199.107 167.196 165.192 1.00 82.27  ? 524  PRO C CA  1 
ATOM   9768  C C   . PRO B 2 506 ? 199.810 168.469 165.679 1.00 82.27  ? 524  PRO C C   1 
ATOM   9769  O O   . PRO B 2 506 ? 201.038 168.511 165.778 1.00 82.27  ? 524  PRO C O   1 
ATOM   9770  C CB  . PRO B 2 506 ? 198.999 166.193 166.345 1.00 140.58 ? 524  PRO C CB  1 
ATOM   9771  C CG  . PRO B 2 506 ? 199.277 164.836 165.713 1.00 140.58 ? 524  PRO C CG  1 
ATOM   9772  C CD  . PRO B 2 506 ? 200.211 165.175 164.561 1.00 140.58 ? 524  PRO C CD  1 
ATOM   9773  N N   . CYS B 2 507 ? 199.028 169.470 166.088 1.00 84.59  ? 525  CYS C N   1 
ATOM   9774  C CA  . CYS B 2 507 ? 199.504 170.543 166.972 1.00 84.59  ? 525  CYS C CA  1 
ATOM   9775  C C   . CYS B 2 507 ? 199.597 170.071 168.446 1.00 84.59  ? 525  CYS C C   1 
ATOM   9776  O O   . CYS B 2 507 ? 199.478 168.883 168.758 1.00 84.59  ? 525  CYS C O   1 
ATOM   9777  C CB  . CYS B 2 507 ? 198.585 171.764 166.795 1.00 109.62 ? 525  CYS C CB  1 
ATOM   9778  S SG  . CYS B 2 507 ? 198.821 172.682 165.250 1.00 109.62 ? 525  CYS C SG  1 
ATOM   9779  N N   . GLN B 2 508 ? 199.832 171.002 169.367 1.00 69.21  ? 526  GLN C N   1 
ATOM   9780  C CA  . GLN B 2 508 ? 199.947 170.796 170.814 1.00 69.21  ? 526  GLN C CA  1 
ATOM   9781  C C   . GLN B 2 508 ? 198.859 171.522 171.617 1.00 69.21  ? 526  GLN C C   1 
ATOM   9782  O O   . GLN B 2 508 ? 198.300 172.517 171.163 1.00 69.21  ? 526  GLN C O   1 
ATOM   9783  C CB  . GLN B 2 508 ? 201.386 171.069 171.265 1.00 94.07  ? 526  GLN C CB  1 
ATOM   9784  C CG  . GLN B 2 508 ? 202.285 169.874 170.927 1.00 94.07  ? 526  GLN C CG  1 
ATOM   9785  C CD  . GLN B 2 508 ? 201.848 168.597 171.645 1.00 94.07  ? 526  GLN C CD  1 
ATOM   9786  O OE1 . GLN B 2 508 ? 202.073 168.418 172.830 1.00 94.07  ? 526  GLN C OE1 1 
ATOM   9787  N NE2 . GLN B 2 508 ? 201.174 167.683 170.988 1.00 94.07  ? 526  GLN C NE2 1 
ATOM   9788  N N   . PRO B 2 509 ? 198.475 170.970 172.783 1.00 62.64  ? 527  PRO C N   1 
ATOM   9789  C CA  . PRO B 2 509 ? 197.137 171.120 173.368 1.00 62.64  ? 527  PRO C CA  1 
ATOM   9790  C C   . PRO B 2 509 ? 196.844 172.449 174.080 1.00 62.64  ? 527  PRO C C   1 
ATOM   9791  O O   . PRO B 2 509 ? 196.259 172.504 175.156 1.00 62.64  ? 527  PRO C O   1 
ATOM   9792  C CB  . PRO B 2 509 ? 196.995 169.903 174.275 1.00 107.04 ? 527  PRO C CB  1 
ATOM   9793  C CG  . PRO B 2 509 ? 198.413 169.669 174.765 1.00 107.04 ? 527  PRO C CG  1 
ATOM   9794  C CD  . PRO B 2 509 ? 199.201 169.932 173.497 1.00 107.04 ? 527  PRO C CD  1 
ATOM   9795  N N   . TYR B 2 510 ? 197.232 173.557 173.469 1.00 63.94  ? 528  TYR C N   1 
ATOM   9796  C CA  . TYR B 2 510 ? 197.044 174.923 173.960 1.00 63.94  ? 528  TYR C CA  1 
ATOM   9797  C C   . TYR B 2 510 ? 196.871 175.936 172.809 1.00 63.94  ? 528  TYR C C   1 
ATOM   9798  O O   . TYR B 2 510 ? 196.711 177.131 173.036 1.00 63.94  ? 528  TYR C O   1 
ATOM   9799  C CB  . TYR B 2 510 ? 198.221 175.265 174.889 1.00 88.61  ? 528  TYR C CB  1 
ATOM   9800  C CG  . TYR B 2 510 ? 199.603 174.856 174.398 1.00 88.61  ? 528  TYR C CG  1 
ATOM   9801  C CD1 . TYR B 2 510 ? 200.371 175.736 173.615 1.00 88.61  ? 528  TYR C CD1 1 
ATOM   9802  C CD2 . TYR B 2 510 ? 200.118 173.587 174.733 1.00 88.61  ? 528  TYR C CD2 1 
ATOM   9803  C CE1 . TYR B 2 510 ? 201.638 175.346 173.149 1.00 88.61  ? 528  TYR C CE1 1 
ATOM   9804  C CE2 . TYR B 2 510 ? 201.394 173.202 174.285 1.00 88.61  ? 528  TYR C CE2 1 
ATOM   9805  C CZ  . TYR B 2 510 ? 202.152 174.077 173.481 1.00 88.61  ? 528  TYR C CZ  1 
ATOM   9806  O OH  . TYR B 2 510 ? 203.373 173.704 173.025 1.00 88.61  ? 528  TYR C OH  1 
ATOM   9807  N N   . GLU B 2 511 ? 196.899 175.473 171.561 1.00 67.41  ? 529  GLU C N   1 
ATOM   9808  C CA  . GLU B 2 511 ? 197.060 176.318 170.376 1.00 67.41  ? 529  GLU C CA  1 
ATOM   9809  C C   . GLU B 2 511 ? 195.752 176.463 169.562 1.00 67.41  ? 529  GLU C C   1 
ATOM   9810  O O   . GLU B 2 511 ? 194.702 175.933 169.934 1.00 67.41  ? 529  GLU C O   1 
ATOM   9811  C CB  . GLU B 2 511 ? 198.229 175.757 169.538 1.00 88.84  ? 529  GLU C CB  1 
ATOM   9812  C CG  . GLU B 2 511 ? 199.537 175.576 170.320 1.00 88.84  ? 529  GLU C CG  1 
ATOM   9813  C CD  . GLU B 2 511 ? 200.641 174.890 169.500 1.00 88.84  ? 529  GLU C CD  1 
ATOM   9814  O OE1 . GLU B 2 511 ? 200.403 173.818 168.895 1.00 88.84  ? 529  GLU C OE1 1 
ATOM   9815  O OE2 . GLU B 2 511 ? 201.778 175.414 169.503 1.00 88.84  ? 529  GLU C OE2 1 
ATOM   9816  N N   . TYR B 2 512 ? 195.804 177.218 168.464 1.00 72.62  ? 530  TYR C N   1 
ATOM   9817  C CA  . TYR B 2 512 ? 194.723 177.422 167.498 1.00 72.62  ? 530  TYR C CA  1 
ATOM   9818  C C   . TYR B 2 512 ? 195.253 177.604 166.082 1.00 72.62  ? 530  TYR C C   1 
ATOM   9819  O O   . TYR B 2 512 ? 196.417 177.948 165.899 1.00 72.62  ? 530  TYR C O   1 
ATOM   9820  C CB  . TYR B 2 512 ? 193.865 178.617 167.900 1.00 97.48  ? 530  TYR C CB  1 
ATOM   9821  C CG  . TYR B 2 512 ? 194.402 180.011 167.654 1.00 97.48  ? 530  TYR C CG  1 
ATOM   9822  C CD1 . TYR B 2 512 ? 195.208 180.635 168.621 1.00 97.48  ? 530  TYR C CD1 1 
ATOM   9823  C CD2 . TYR B 2 512 ? 193.966 180.736 166.532 1.00 97.48  ? 530  TYR C CD2 1 
ATOM   9824  C CE1 . TYR B 2 512 ? 195.537 181.996 168.496 1.00 97.48  ? 530  TYR C CE1 1 
ATOM   9825  C CE2 . TYR B 2 512 ? 194.314 182.090 166.389 1.00 97.48  ? 530  TYR C CE2 1 
ATOM   9826  C CZ  . TYR B 2 512 ? 195.081 182.729 167.383 1.00 97.48  ? 530  TYR C CZ  1 
ATOM   9827  O OH  . TYR B 2 512 ? 195.366 184.051 167.278 1.00 97.48  ? 530  TYR C OH  1 
ATOM   9828  N N   . ARG B 2 513 ? 194.413 177.360 165.076 1.00 72.08  ? 531  ARG C N   1 
ATOM   9829  C CA  . ARG B 2 513 ? 194.843 177.281 163.683 1.00 72.08  ? 531  ARG C CA  1 
ATOM   9830  C C   . ARG B 2 513 ? 195.733 178.457 163.241 1.00 72.08  ? 531  ARG C C   1 
ATOM   9831  O O   . ARG B 2 513 ? 195.348 179.623 163.366 1.00 72.08  ? 531  ARG C O   1 
ATOM   9832  C CB  . ARG B 2 513 ? 193.596 177.182 162.813 1.00 101.23 ? 531  ARG C CB  1 
ATOM   9833  N N   . LEU B 2 514 ? 196.918 178.138 162.705 1.00 70.19  ? 532  LEU C N   1 
ATOM   9834  C CA  . LEU B 2 514 ? 197.897 179.090 162.175 1.00 70.19  ? 532  LEU C CA  1 
ATOM   9835  C C   . LEU B 2 514 ? 198.636 178.470 160.981 1.00 70.19  ? 532  LEU C C   1 
ATOM   9836  O O   . LEU B 2 514 ? 199.357 177.493 161.135 1.00 70.19  ? 532  LEU C O   1 
ATOM   9837  C CB  . LEU B 2 514 ? 198.873 179.477 163.295 1.00 103.09 ? 532  LEU C CB  1 
ATOM   9838  C CG  . LEU B 2 514 ? 199.985 180.438 162.856 1.00 103.09 ? 532  LEU C CG  1 
ATOM   9839  C CD1 . LEU B 2 514 ? 199.410 181.815 162.546 1.00 103.09 ? 532  LEU C CD1 1 
ATOM   9840  C CD2 . LEU B 2 514 ? 201.042 180.580 163.954 1.00 103.09 ? 532  LEU C CD2 1 
ATOM   9841  N N   . ASP B 2 515 ? 198.493 179.055 159.795 1.00 68.60  ? 533  ASP C N   1 
ATOM   9842  C CA  . ASP B 2 515 ? 198.950 178.450 158.537 1.00 68.60  ? 533  ASP C CA  1 
ATOM   9843  C C   . ASP B 2 515 ? 198.238 177.117 158.233 1.00 68.60  ? 533  ASP C C   1 
ATOM   9844  O O   . ASP B 2 515 ? 197.348 176.660 158.951 1.00 68.60  ? 533  ASP C O   1 
ATOM   9845  C CB  . ASP B 2 515 ? 200.489 178.312 158.506 1.00 88.05  ? 533  ASP C CB  1 
ATOM   9846  C CG  . ASP B 2 515 ? 201.248 179.532 159.042 1.00 88.05  ? 533  ASP C CG  1 
ATOM   9847  O OD1 . ASP B 2 515 ? 200.776 180.671 158.831 1.00 88.05  ? 533  ASP C OD1 1 
ATOM   9848  O OD2 . ASP B 2 515 ? 202.347 179.373 159.615 1.00 88.05  ? 533  ASP C OD2 1 
ATOM   9849  N N   . GLU B 2 516 ? 198.624 176.464 157.144 1.00 68.45  ? 534  GLU C N   1 
ATOM   9850  C CA  . GLU B 2 516 ? 198.225 175.092 156.829 1.00 68.45  ? 534  GLU C CA  1 
ATOM   9851  C C   . GLU B 2 516 ? 199.023 174.030 157.606 1.00 68.45  ? 534  GLU C C   1 
ATOM   9852  O O   . GLU B 2 516 ? 198.730 172.844 157.484 1.00 68.45  ? 534  GLU C O   1 
ATOM   9853  C CB  . GLU B 2 516 ? 198.308 174.864 155.308 1.00 90.21  ? 534  GLU C CB  1 
ATOM   9854  C CG  . GLU B 2 516 ? 199.721 174.818 154.710 1.00 90.21  ? 534  GLU C CG  1 
ATOM   9855  C CD  . GLU B 2 516 ? 200.250 176.183 154.236 1.00 90.21  ? 534  GLU C CD  1 
ATOM   9856  O OE1 . GLU B 2 516 ? 200.144 177.180 154.980 1.00 90.21  ? 534  GLU C OE1 1 
ATOM   9857  O OE2 . GLU B 2 516 ? 200.778 176.262 153.107 1.00 90.21  ? 534  GLU C OE2 1 
ATOM   9858  N N   . PHE B 2 517 ? 200.038 174.435 158.379 1.00 69.68  ? 535  PHE C N   1 
ATOM   9859  C CA  . PHE B 2 517 ? 201.067 173.529 158.900 1.00 69.68  ? 535  PHE C CA  1 
ATOM   9860  C C   . PHE B 2 517 ? 201.430 173.699 160.395 1.00 69.68  ? 535  PHE C C   1 
ATOM   9861  O O   . PHE B 2 517 ? 202.276 172.959 160.898 1.00 69.68  ? 535  PHE C O   1 
ATOM   9862  C CB  . PHE B 2 517 ? 202.313 173.645 158.010 1.00 97.18  ? 535  PHE C CB  1 
ATOM   9863  C CG  . PHE B 2 517 ? 203.051 174.961 158.142 1.00 97.18  ? 535  PHE C CG  1 
ATOM   9864  C CD1 . PHE B 2 517 ? 203.973 175.145 159.188 1.00 97.18  ? 535  PHE C CD1 1 
ATOM   9865  C CD2 . PHE B 2 517 ? 202.841 175.985 157.207 1.00 97.18  ? 535  PHE C CD2 1 
ATOM   9866  C CE1 . PHE B 2 517 ? 204.671 176.353 159.314 1.00 97.18  ? 535  PHE C CE1 1 
ATOM   9867  C CE2 . PHE B 2 517 ? 203.552 177.191 157.325 1.00 97.18  ? 535  PHE C CE2 1 
ATOM   9868  C CZ  . PHE B 2 517 ? 204.459 177.377 158.380 1.00 97.18  ? 535  PHE C CZ  1 
ATOM   9869  N N   . THR B 2 518 ? 200.842 174.653 161.134 1.00 73.07  ? 536  THR C N   1 
ATOM   9870  C CA  . THR B 2 518 ? 201.129 174.860 162.572 1.00 73.07  ? 536  THR C CA  1 
ATOM   9871  C C   . THR B 2 518 ? 199.916 175.440 163.338 1.00 73.07  ? 536  THR C C   1 
ATOM   9872  O O   . THR B 2 518 ? 198.788 175.395 162.849 1.00 73.07  ? 536  THR C O   1 
ATOM   9873  C CB  . THR B 2 518 ? 202.433 175.673 162.731 1.00 102.17 ? 536  THR C CB  1 
ATOM   9874  O OG1 . THR B 2 518 ? 202.893 175.615 164.063 1.00 102.17 ? 536  THR C OG1 1 
ATOM   9875  C CG2 . THR B 2 518 ? 202.316 177.145 162.351 1.00 102.17 ? 536  THR C CG2 1 
ATOM   9876  N N   . CYS B 2 519 ? 200.112 175.909 164.573 1.00 74.86  ? 537  CYS C N   1 
ATOM   9877  C CA  . CYS B 2 519 ? 199.083 176.550 165.386 1.00 74.86  ? 537  CYS C CA  1 
ATOM   9878  C C   . CYS B 2 519 ? 199.673 177.660 166.272 1.00 74.86  ? 537  CYS C C   1 
ATOM   9879  O O   . CYS B 2 519 ? 200.752 177.515 166.841 1.00 74.86  ? 537  CYS C O   1 
ATOM   9880  C CB  . CYS B 2 519 ? 198.367 175.511 166.248 1.00 97.01  ? 537  CYS C CB  1 
ATOM   9881  S SG  . CYS B 2 519 ? 197.470 174.202 165.391 1.00 97.01  ? 537  CYS C SG  1 
ATOM   9882  N N   . ALA B 2 520 ? 198.953 178.761 166.426 1.00 70.93  ? 538  ALA C N   1 
ATOM   9883  C CA  . ALA B 2 520 ? 199.257 179.860 167.327 1.00 70.93  ? 538  ALA C CA  1 
ATOM   9884  C C   . ALA B 2 520 ? 198.936 179.461 168.769 1.00 70.93  ? 538  ALA C C   1 
ATOM   9885  O O   . ALA B 2 520 ? 197.891 178.879 169.019 1.00 70.93  ? 538  ALA C O   1 
ATOM   9886  C CB  . ALA B 2 520 ? 198.416 181.067 166.906 1.00 95.82  ? 538  ALA C CB  1 
ATOM   9887  N N   . ASP B 2 521 ? 199.784 179.798 169.733 1.00 76.79  ? 539  ASP C N   1 
ATOM   9888  C CA  . ASP B 2 521 ? 199.455 179.668 171.161 1.00 76.79  ? 539  ASP C CA  1 
ATOM   9889  C C   . ASP B 2 521 ? 198.261 180.579 171.516 1.00 76.79  ? 539  ASP C C   1 
ATOM   9890  O O   . ASP B 2 521 ? 198.255 181.766 171.172 1.00 76.79  ? 539  ASP C O   1 
ATOM   9891  C CB  . ASP B 2 521 ? 200.716 180.012 171.973 1.00 97.78  ? 539  ASP C CB  1 
ATOM   9892  C CG  . ASP B 2 521 ? 200.600 179.819 173.489 1.00 97.78  ? 539  ASP C CG  1 
ATOM   9893  O OD1 . ASP B 2 521 ? 199.671 179.129 173.949 1.00 97.78  ? 539  ASP C OD1 1 
ATOM   9894  O OD2 . ASP B 2 521 ? 201.484 180.329 174.216 1.00 97.78  ? 539  ASP C OD2 1 
ATOM   9895  N N   . CYS B 2 522 ? 197.231 180.041 172.170 1.00 84.65  ? 540  CYS C N   1 
ATOM   9896  C CA  . CYS B 2 522 ? 196.069 180.821 172.597 1.00 84.65  ? 540  CYS C CA  1 
ATOM   9897  C C   . CYS B 2 522 ? 196.388 181.702 173.813 1.00 84.65  ? 540  CYS C C   1 
ATOM   9898  O O   . CYS B 2 522 ? 197.521 181.783 174.293 1.00 84.65  ? 540  CYS C O   1 
ATOM   9899  C CB  . CYS B 2 522 ? 194.926 179.861 172.959 1.00 112.75 ? 540  CYS C CB  1 
ATOM   9900  S SG  . CYS B 2 522 ? 194.494 178.775 171.586 1.00 112.75 ? 540  CYS C SG  1 
ATOM   9901  N N   . GLY B 2 523 ? 195.349 182.319 174.383 1.00 78.62  ? 541  GLY C N   1 
ATOM   9902  C CA  . GLY B 2 523 ? 195.377 182.638 175.804 1.00 78.62  ? 541  GLY C CA  1 
ATOM   9903  C C   . GLY B 2 523 ? 195.512 181.367 176.651 1.00 78.62  ? 541  GLY C C   1 
ATOM   9904  O O   . GLY B 2 523 ? 195.502 180.239 176.161 1.00 78.62  ? 541  GLY C O   1 
ATOM   9905  N N   . LEU B 2 524 ? 195.607 181.559 177.954 1.00 65.05  ? 542  LEU C N   1 
ATOM   9906  C CA  . LEU B 2 524 ? 195.611 180.484 178.944 1.00 65.05  ? 542  LEU C CA  1 
ATOM   9907  C C   . LEU B 2 524 ? 194.334 179.640 178.956 1.00 65.05  ? 542  LEU C C   1 
ATOM   9908  O O   . LEU B 2 524 ? 193.222 180.164 179.046 1.00 65.05  ? 542  LEU C O   1 
ATOM   9909  C CB  . LEU B 2 524 ? 195.860 181.070 180.344 1.00 95.54  ? 542  LEU C CB  1 
ATOM   9910  C CG  . LEU B 2 524 ? 195.879 180.065 181.560 1.00 95.54  ? 542  LEU C CG  1 
ATOM   9911  C CD1 . LEU B 2 524 ? 197.056 179.078 181.450 1.00 95.54  ? 542  LEU C CD1 1 
ATOM   9912  C CD2 . LEU B 2 524 ? 196.003 180.871 182.861 1.00 95.54  ? 542  LEU C CD2 1 
ATOM   9913  N N   . GLY B 2 525 ? 194.506 178.333 178.900 1.00 63.23  ? 543  GLY C N   1 
ATOM   9914  C CA  . GLY B 2 525 ? 193.429 177.361 178.830 1.00 63.23  ? 543  GLY C CA  1 
ATOM   9915  C C   . GLY B 2 525 ? 193.874 176.155 178.016 1.00 63.23  ? 543  GLY C C   1 
ATOM   9916  O O   . GLY B 2 525 ? 194.949 176.155 177.412 1.00 63.23  ? 543  GLY C O   1 
ATOM   9917  N N   . TYR B 2 526 ? 193.077 175.101 178.012 1.00 68.68  ? 544  TYR C N   1 
ATOM   9918  C CA  . TYR B 2 526 ? 193.432 173.887 177.275 1.00 68.68  ? 544  TYR C CA  1 
ATOM   9919  C C   . TYR B 2 526 ? 192.924 174.017 175.865 1.00 68.68  ? 544  TYR C C   1 
ATOM   9920  O O   . TYR B 2 526 ? 191.730 174.228 175.658 1.00 68.68  ? 544  TYR C O   1 
ATOM   9921  C CB  . TYR B 2 526 ? 192.824 172.649 177.901 1.00 95.18  ? 544  TYR C CB  1 
ATOM   9922  C CG  . TYR B 2 526 ? 193.149 171.413 177.145 1.00 95.18  ? 544  TYR C CG  1 
ATOM   9923  C CD1 . TYR B 2 526 ? 192.319 170.997 176.106 1.00 95.18  ? 544  TYR C CD1 1 
ATOM   9924  C CD2 . TYR B 2 526 ? 194.279 170.699 177.460 1.00 95.18  ? 544  TYR C CD2 1 
ATOM   9925  C CE1 . TYR B 2 526 ? 192.620 169.872 175.395 1.00 95.18  ? 544  TYR C CE1 1 
ATOM   9926  C CE2 . TYR B 2 526 ? 194.572 169.557 176.754 1.00 95.18  ? 544  TYR C CE2 1 
ATOM   9927  C CZ  . TYR B 2 526 ? 193.735 169.147 175.713 1.00 95.18  ? 544  TYR C CZ  1 
ATOM   9928  O OH  . TYR B 2 526 ? 194.030 168.007 175.002 1.00 95.18  ? 544  TYR C OH  1 
ATOM   9929  N N   . TRP B 2 527 ? 193.804 173.835 174.881 1.00 73.99  ? 545  TRP C N   1 
ATOM   9930  C CA  . TRP B 2 527 ? 193.500 173.857 173.445 1.00 73.99  ? 545  TRP C CA  1 
ATOM   9931  C C   . TRP B 2 527 ? 192.430 174.907 173.025 1.00 73.99  ? 545  TRP C C   1 
ATOM   9932  O O   . TRP B 2 527 ? 191.477 174.549 172.329 1.00 73.99  ? 545  TRP C O   1 
ATOM   9933  C CB  . TRP B 2 527 ? 193.165 172.404 173.050 1.00 102.70 ? 545  TRP C CB  1 
ATOM   9934  C CG  . TRP B 2 527 ? 192.911 172.113 171.605 1.00 102.70 ? 545  TRP C CG  1 
ATOM   9935  C CD1 . TRP B 2 527 ? 191.728 171.706 171.093 1.00 102.70 ? 545  TRP C CD1 1 
ATOM   9936  C CD2 . TRP B 2 527 ? 193.820 172.207 170.470 1.00 102.70 ? 545  TRP C CD2 1 
ATOM   9937  N NE1 . TRP B 2 527 ? 191.831 171.581 169.725 1.00 102.70 ? 545  TRP C NE1 1 
ATOM   9938  C CE2 . TRP B 2 527 ? 193.092 171.899 169.285 1.00 102.70 ? 545  TRP C CE2 1 
ATOM   9939  C CE3 . TRP B 2 527 ? 195.178 172.541 170.312 1.00 102.70 ? 545  TRP C CE3 1 
ATOM   9940  C CZ2 . TRP B 2 527 ? 193.665 171.959 168.010 1.00 102.70 ? 545  TRP C CZ2 1 
ATOM   9941  C CZ3 . TRP B 2 527 ? 195.771 172.584 169.036 1.00 102.70 ? 545  TRP C CZ3 1 
ATOM   9942  C CH2 . TRP B 2 527 ? 195.017 172.305 167.884 1.00 102.70 ? 545  TRP C CH2 1 
ATOM   9943  N N   . PRO B 2 528 ? 192.481 176.184 173.477 1.00 76.11  ? 546  PRO C N   1 
ATOM   9944  C CA  . PRO B 2 528 ? 191.311 177.076 173.408 1.00 76.11  ? 546  PRO C CA  1 
ATOM   9945  C C   . PRO B 2 528 ? 190.747 177.421 172.025 1.00 76.11  ? 546  PRO C C   1 
ATOM   9946  O O   . PRO B 2 528 ? 189.711 178.085 171.962 1.00 76.11  ? 546  PRO C O   1 
ATOM   9947  C CB  . PRO B 2 528 ? 191.724 178.372 174.106 1.00 130.06 ? 546  PRO C CB  1 
ATOM   9948  C CG  . PRO B 2 528 ? 192.807 177.918 175.065 1.00 130.06 ? 546  PRO C CG  1 
ATOM   9949  C CD  . PRO B 2 528 ? 193.516 176.820 174.287 1.00 130.06 ? 546  PRO C CD  1 
ATOM   9950  N N   . ASN B 2 529 ? 191.414 177.064 170.922 1.00 80.69  ? 547  ASN C N   1 
ATOM   9951  C CA  . ASN B 2 529 ? 191.081 177.547 169.578 1.00 80.69  ? 547  ASN C CA  1 
ATOM   9952  C C   . ASN B 2 529 ? 190.921 179.091 169.553 1.00 80.69  ? 547  ASN C C   1 
ATOM   9953  O O   . ASN B 2 529 ? 189.949 179.630 169.021 1.00 80.69  ? 547  ASN C O   1 
ATOM   9954  C CB  . ASN B 2 529 ? 189.896 176.761 168.990 1.00 109.05 ? 547  ASN C CB  1 
ATOM   9955  C CG  . ASN B 2 529 ? 189.716 176.993 167.498 1.00 109.05 ? 547  ASN C CG  1 
ATOM   9956  O OD1 . ASN B 2 529 ? 190.605 177.424 166.780 1.00 109.05 ? 547  ASN C OD1 1 
ATOM   9957  N ND2 . ASN B 2 529 ? 188.556 176.701 166.967 1.00 109.05 ? 547  ASN C ND2 1 
ATOM   9958  N N   . ALA B 2 530 ? 191.851 179.791 170.221 1.00 76.49  ? 548  ALA C N   1 
ATOM   9959  C CA  . ALA B 2 530 ? 191.813 181.191 170.645 1.00 76.49  ? 548  ALA C CA  1 
ATOM   9960  C C   . ALA B 2 530 ? 190.690 181.490 171.645 1.00 76.49  ? 548  ALA C C   1 
ATOM   9961  O O   . ALA B 2 530 ? 190.966 181.930 172.766 1.00 76.49  ? 548  ALA C O   1 
ATOM   9962  C CB  . ALA B 2 530 ? 191.805 182.135 169.442 1.00 103.33 ? 548  ALA C CB  1 
ATOM   9963  N N   . ASP B 2 547 ? 186.035 172.151 193.154 1.00 183.64 ? 565  ASP C N   1 
ATOM   9964  C CA  . ASP B 2 547 ? 185.189 172.455 194.306 1.00 183.64 ? 565  ASP C CA  1 
ATOM   9965  C C   . ASP B 2 547 ? 183.985 171.478 194.488 1.00 183.64 ? 565  ASP C C   1 
ATOM   9966  O O   . ASP B 2 547 ? 183.075 171.748 195.283 1.00 183.64 ? 565  ASP C O   1 
ATOM   9967  C CB  . ASP B 2 547 ? 184.720 173.960 194.230 1.00 233.84 ? 565  ASP C CB  1 
ATOM   9968  C CG  . ASP B 2 547 ? 183.863 174.370 192.959 1.00 233.84 ? 565  ASP C CG  1 
ATOM   9969  O OD1 . ASP B 2 547 ? 183.759 173.575 192.052 1.00 233.84 ? 565  ASP C OD1 1 
ATOM   9970  O OD2 . ASP B 2 547 ? 183.364 175.463 192.949 1.00 233.84 ? 565  ASP C OD2 1 
ATOM   9971  N N   . ALA B 2 548 ? 184.029 170.274 193.856 1.00 189.55 ? 566  ALA C N   1 
ATOM   9972  C CA  . ALA B 2 548 ? 182.947 169.264 193.873 1.00 189.55 ? 566  ALA C CA  1 
ATOM   9973  C C   . ALA B 2 548 ? 182.561 168.809 195.272 1.00 189.55 ? 566  ALA C C   1 
ATOM   9974  O O   . ALA B 2 548 ? 181.398 168.527 195.545 1.00 189.55 ? 566  ALA C O   1 
ATOM   9975  C CB  . ALA B 2 548 ? 183.365 168.040 193.079 1.00 256.07 ? 566  ALA C CB  1 
ATOM   9976  N N   . TRP B 2 549 ? 183.538 168.741 196.159 1.00 189.35 ? 567  TRP C N   1 
ATOM   9977  C CA  . TRP B 2 549 ? 183.282 168.313 197.513 1.00 189.35 ? 567  TRP C CA  1 
ATOM   9978  C C   . TRP B 2 549 ? 183.364 169.483 198.483 1.00 189.35 ? 567  TRP C C   1 
ATOM   9979  O O   . TRP B 2 549 ? 183.443 169.264 199.689 1.00 189.35 ? 567  TRP C O   1 
ATOM   9980  C CB  . TRP B 2 549 ? 184.278 167.227 197.924 1.00 253.51 ? 567  TRP C CB  1 
ATOM   9981  C CG  . TRP B 2 549 ? 184.184 165.936 197.125 1.00 253.51 ? 567  TRP C CG  1 
ATOM   9982  C CD1 . TRP B 2 549 ? 183.185 165.539 196.281 1.00 253.51 ? 567  TRP C CD1 1 
ATOM   9983  C CD2 . TRP B 2 549 ? 185.159 164.864 197.113 1.00 253.51 ? 567  TRP C CD2 1 
ATOM   9984  N NE1 . TRP B 2 549 ? 183.476 164.312 195.752 1.00 253.51 ? 567  TRP C NE1 1 
ATOM   9985  C CE2 . TRP B 2 549 ? 184.677 163.883 196.251 1.00 253.51 ? 567  TRP C CE2 1 
ATOM   9986  C CE3 . TRP B 2 549 ? 186.385 164.662 197.761 1.00 253.51 ? 567  TRP C CE3 1 
ATOM   9987  C CZ2 . TRP B 2 549 ? 185.373 162.713 196.012 1.00 253.51 ? 567  TRP C CZ2 1 
ATOM   9988  C CZ3 . TRP B 2 549 ? 187.083 163.488 197.521 1.00 253.51 ? 567  TRP C CZ3 1 
ATOM   9989  C CH2 . TRP B 2 549 ? 186.590 162.540 196.670 1.00 253.51 ? 567  TRP C CH2 1 
ATOM   9990  N N   . ALA B 2 550 ? 183.267 170.723 197.970 1.00 193.73 ? 568  ALA C N   1 
ATOM   9991  C CA  . ALA B 2 550 ? 183.352 171.959 198.761 1.00 193.73 ? 568  ALA C CA  1 
ATOM   9992  C C   . ALA B 2 550 ? 182.213 172.059 199.747 1.00 193.73 ? 568  ALA C C   1 
ATOM   9993  O O   . ALA B 2 550 ? 182.292 172.762 200.754 1.00 193.73 ? 568  ALA C O   1 
ATOM   9994  C CB  . ALA B 2 550 ? 183.345 173.175 197.870 1.00 261.72 ? 568  ALA C CB  1 
ATOM   9995  N N   . VAL B 2 551 ? 181.168 171.324 199.476 1.00 195.86 ? 569  VAL C N   1 
ATOM   9996  C CA  . VAL B 2 551 ? 180.020 171.273 200.333 1.00 195.86 ? 569  VAL C CA  1 
ATOM   9997  C C   . VAL B 2 551 ? 180.407 170.656 201.677 1.00 195.86 ? 569  VAL C C   1 
ATOM   9998  O O   . VAL B 2 551 ? 179.760 170.919 202.699 1.00 195.86 ? 569  VAL C O   1 
ATOM   9999  C CB  . VAL B 2 551 ? 178.922 170.458 199.633 1.00 283.87 ? 569  VAL C CB  1 
ATOM   10000 C CG1 . VAL B 2 551 ? 178.538 171.164 198.337 1.00 283.87 ? 569  VAL C CG1 1 
ATOM   10001 C CG2 . VAL B 2 551 ? 179.421 169.021 199.313 1.00 283.87 ? 569  VAL C CG2 1 
ATOM   10002 N N   . GLY B 2 552 ? 181.444 169.811 201.660 1.00 190.03 ? 570  GLY C N   1 
ATOM   10003 C CA  . GLY B 2 552 ? 181.978 169.148 202.822 1.00 190.03 ? 570  GLY C CA  1 
ATOM   10004 C C   . GLY B 2 552 ? 182.387 170.158 203.876 1.00 190.03 ? 570  GLY C C   1 
ATOM   10005 O O   . GLY B 2 552 ? 181.829 170.128 204.979 1.00 190.03 ? 570  GLY C O   1 
ATOM   10006 N N   . PRO B 2 553 ? 183.406 171.008 203.613 1.00 178.38 ? 571  PRO C N   1 
ATOM   10007 C CA  . PRO B 2 553 ? 183.859 172.047 204.495 1.00 178.38 ? 571  PRO C CA  1 
ATOM   10008 C C   . PRO B 2 553 ? 182.822 173.095 204.813 1.00 178.38 ? 571  PRO C C   1 
ATOM   10009 O O   . PRO B 2 553 ? 182.823 173.628 205.917 1.00 178.38 ? 571  PRO C O   1 
ATOM   10010 C CB  . PRO B 2 553 ? 185.039 172.621 203.757 1.00 364.07 ? 571  PRO C CB  1 
ATOM   10011 C CG  . PRO B 2 553 ? 184.908 172.220 202.380 1.00 364.07 ? 571  PRO C CG  1 
ATOM   10012 C CD  . PRO B 2 553 ? 184.230 170.874 202.423 1.00 364.07 ? 571  PRO C CD  1 
ATOM   10013 N N   . VAL B 2 554 ? 181.856 173.328 203.930 1.00 183.82 ? 572  VAL C N   1 
ATOM   10014 C CA  . VAL B 2 554 ? 180.857 174.300 204.312 1.00 183.82 ? 572  VAL C CA  1 
ATOM   10015 C C   . VAL B 2 554 ? 180.020 173.704 205.415 1.00 183.82 ? 572  VAL C C   1 
ATOM   10016 O O   . VAL B 2 554 ? 179.716 174.377 206.411 1.00 183.82 ? 572  VAL C O   1 
ATOM   10017 C CB  . VAL B 2 554 ? 179.987 174.721 203.121 1.00 266.42 ? 572  VAL C CB  1 
ATOM   10018 C CG1 . VAL B 2 554 ? 178.811 175.603 203.584 1.00 266.42 ? 572  VAL C CG1 1 
ATOM   10019 C CG2 . VAL B 2 554 ? 180.853 175.502 202.144 1.00 266.42 ? 572  VAL C CG2 1 
ATOM   10020 N N   . THR B 2 555 ? 179.631 172.447 205.223 1.00 180.98 ? 573  THR C N   1 
ATOM   10021 C CA  . THR B 2 555 ? 178.801 171.761 206.175 1.00 180.98 ? 573  THR C CA  1 
ATOM   10022 C C   . THR B 2 555 ? 179.499 171.591 207.503 1.00 180.98 ? 573  THR C C   1 
ATOM   10023 O O   . THR B 2 555 ? 178.933 171.928 208.545 1.00 180.98 ? 573  THR C O   1 
ATOM   10024 C CB  . THR B 2 555 ? 178.411 170.365 205.642 1.00 253.06 ? 573  THR C CB  1 
ATOM   10025 O OG1 . THR B 2 555 ? 177.677 170.504 204.417 1.00 253.06 ? 573  THR C OG1 1 
ATOM   10026 C CG2 . THR B 2 555 ? 177.543 169.640 206.666 1.00 253.06 ? 573  THR C CG2 1 
ATOM   10027 N N   . ILE B 2 556 ? 180.747 171.134 207.493 1.00 181.89 ? 574  ILE C N   1 
ATOM   10028 C CA  . ILE B 2 556 ? 181.401 170.934 208.770 1.00 181.89 ? 574  ILE C CA  1 
ATOM   10029 C C   . ILE B 2 556 ? 181.709 172.234 209.459 1.00 181.89 ? 574  ILE C C   1 
ATOM   10030 O O   . ILE B 2 556 ? 181.704 172.283 210.687 1.00 181.89 ? 574  ILE C O   1 
ATOM   10031 C CB  . ILE B 2 556 ? 182.680 170.083 208.677 1.00 268.06 ? 574  ILE C CB  1 
ATOM   10032 C CG1 . ILE B 2 556 ? 183.110 169.634 210.102 1.00 268.06 ? 574  ILE C CG1 1 
ATOM   10033 C CG2 . ILE B 2 556 ? 183.746 170.792 207.981 1.00 268.06 ? 574  ILE C CG2 1 
ATOM   10034 C CD1 . ILE B 2 556 ? 184.201 168.628 210.146 1.00 268.06 ? 574  ILE C CD1 1 
ATOM   10035 N N   . ALA B 2 557 ? 182.068 173.279 208.716 1.00 181.76 ? 575  ALA C N   1 
ATOM   10036 C CA  . ALA B 2 557 ? 182.372 174.517 209.373 1.00 181.76 ? 575  ALA C CA  1 
ATOM   10037 C C   . ALA B 2 557 ? 181.155 175.058 210.073 1.00 181.76 ? 575  ALA C C   1 
ATOM   10038 O O   . ALA B 2 557 ? 181.254 175.496 211.224 1.00 181.76 ? 575  ALA C O   1 
ATOM   10039 C CB  . ALA B 2 557 ? 182.886 175.507 208.355 1.00 245.55 ? 575  ALA C CB  1 
ATOM   10040 N N   . CYS B 2 558 ? 180.000 174.961 209.422 1.00 179.06 ? 576  CYS C N   1 
ATOM   10041 C CA  . CYS B 2 558 ? 178.794 175.482 210.011 1.00 179.06 ? 576  CYS C CA  1 
ATOM   10042 C C   . CYS B 2 558 ? 178.410 174.663 211.236 1.00 179.06 ? 576  CYS C C   1 
ATOM   10043 O O   . CYS B 2 558 ? 178.075 175.228 212.284 1.00 179.06 ? 576  CYS C O   1 
ATOM   10044 C CB  . CYS B 2 558 ? 177.696 175.475 208.966 1.00 240.02 ? 576  CYS C CB  1 
ATOM   10045 S SG  . CYS B 2 558 ? 178.022 176.659 207.619 1.00 240.02 ? 576  CYS C SG  1 
ATOM   10046 N N   . LEU B 2 559 ? 178.513 173.332 211.130 1.00 179.77 ? 577  LEU C N   1 
ATOM   10047 C CA  . LEU B 2 559 ? 178.164 172.469 212.244 1.00 179.77 ? 577  LEU C CA  1 
ATOM   10048 C C   . LEU B 2 559 ? 179.116 172.665 213.392 1.00 179.77 ? 577  LEU C C   1 
ATOM   10049 O O   . LEU B 2 559 ? 178.700 172.642 214.556 1.00 179.77 ? 577  LEU C O   1 
ATOM   10050 C CB  . LEU B 2 559 ? 178.218 171.006 211.825 1.00 264.04 ? 577  LEU C CB  1 
ATOM   10051 C CG  . LEU B 2 559 ? 177.166 170.522 210.829 1.00 264.04 ? 577  LEU C CG  1 
ATOM   10052 C CD1 . LEU B 2 559 ? 177.543 169.118 210.409 1.00 264.04 ? 577  LEU C CD1 1 
ATOM   10053 C CD2 . LEU B 2 559 ? 175.774 170.553 211.452 1.00 264.04 ? 577  LEU C CD2 1 
ATOM   10054 N N   . GLY B 2 560 ? 180.394 172.877 213.073 1.00 176.57 ? 578  GLY C N   1 
ATOM   10055 C CA  . GLY B 2 560 ? 181.413 173.102 214.062 1.00 176.57 ? 578  GLY C CA  1 
ATOM   10056 C C   . GLY B 2 560 ? 181.037 174.324 214.860 1.00 176.57 ? 578  GLY C C   1 
ATOM   10057 O O   . GLY B 2 560 ? 181.034 174.278 216.093 1.00 176.57 ? 578  GLY C O   1 
ATOM   10058 N N   . ALA B 2 561 ? 180.721 175.426 214.173 1.00 175.03 ? 579  ALA C N   1 
ATOM   10059 C CA  . ALA B 2 561 ? 180.372 176.651 214.867 1.00 175.03 ? 579  ALA C CA  1 
ATOM   10060 C C   . ALA B 2 561 ? 179.149 176.478 215.754 1.00 175.03 ? 579  ALA C C   1 
ATOM   10061 O O   . ALA B 2 561 ? 179.154 176.943 216.900 1.00 175.03 ? 579  ALA C O   1 
ATOM   10062 C CB  . ALA B 2 561 ? 180.097 177.741 213.865 1.00 236.46 ? 579  ALA C CB  1 
ATOM   10063 N N   . LEU B 2 562 ? 178.143 175.736 215.284 1.00 172.47 ? 580  LEU C N   1 
ATOM   10064 C CA  . LEU B 2 562 ? 176.964 175.548 216.102 1.00 172.47 ? 580  LEU C CA  1 
ATOM   10065 C C   . LEU B 2 562 ? 177.269 174.747 217.341 1.00 172.47 ? 580  LEU C C   1 
ATOM   10066 O O   . LEU B 2 562 ? 176.909 175.152 218.445 1.00 172.47 ? 580  LEU C O   1 
ATOM   10067 C CB  . LEU B 2 562 ? 175.905 174.784 215.306 1.00 253.32 ? 580  LEU C CB  1 
ATOM   10068 C CG  . LEU B 2 562 ? 175.241 175.508 214.147 1.00 253.32 ? 580  LEU C CG  1 
ATOM   10069 C CD1 . LEU B 2 562 ? 174.421 174.499 213.346 1.00 253.32 ? 580  LEU C CD1 1 
ATOM   10070 C CD2 . LEU B 2 562 ? 174.339 176.612 214.681 1.00 253.32 ? 580  LEU C CD2 1 
ATOM   10071 N N   . ALA B 2 563 ? 178.020 173.660 217.186 1.00 163.46 ? 581  ALA C N   1 
ATOM   10072 C CA  . ALA B 2 563 ? 178.334 172.823 218.324 1.00 163.46 ? 581  ALA C CA  1 
ATOM   10073 C C   . ALA B 2 563 ? 179.197 173.562 219.328 1.00 163.46 ? 581  ALA C C   1 
ATOM   10074 O O   . ALA B 2 563 ? 179.007 173.429 220.543 1.00 163.46 ? 581  ALA C O   1 
ATOM   10075 C CB  . ALA B 2 563 ? 179.042 171.571 217.859 1.00 220.83 ? 581  ALA C CB  1 
ATOM   10076 N N   . THR B 2 564 ? 180.110 174.379 218.809 1.00 165.33 ? 582  THR C N   1 
ATOM   10077 C CA  . THR B 2 564 ? 181.052 175.149 219.592 1.00 165.33 ? 582  THR C CA  1 
ATOM   10078 C C   . THR B 2 564 ? 180.347 176.114 220.495 1.00 165.33 ? 582  THR C C   1 
ATOM   10079 O O   . THR B 2 564 ? 180.666 176.210 221.686 1.00 165.33 ? 582  THR C O   1 
ATOM   10080 C CB  . THR B 2 564 ? 181.998 175.898 218.627 1.00 231.18 ? 582  THR C CB  1 
ATOM   10081 O OG1 . THR B 2 564 ? 182.737 174.950 217.904 1.00 231.18 ? 582  THR C OG1 1 
ATOM   10082 C CG2 . THR B 2 564 ? 182.916 176.804 219.307 1.00 231.18 ? 582  THR C CG2 1 
ATOM   10083 N N   . LEU B 2 565 ? 179.366 176.802 219.958 1.00 172.44 ? 583  LEU C N   1 
ATOM   10084 C CA  . LEU B 2 565 ? 178.682 177.770 220.756 1.00 172.44 ? 583  LEU C CA  1 
ATOM   10085 C C   . LEU B 2 565 ? 177.583 177.116 221.610 1.00 172.44 ? 583  LEU C C   1 
ATOM   10086 O O   . LEU B 2 565 ? 177.264 177.622 222.695 1.00 172.44 ? 583  LEU C O   1 
ATOM   10087 C CB  . LEU B 2 565 ? 178.180 178.860 219.830 1.00 253.28 ? 583  LEU C CB  1 
ATOM   10088 C CG  . LEU B 2 565 ? 179.326 179.627 219.021 1.00 253.28 ? 583  LEU C CG  1 
ATOM   10089 C CD1 . LEU B 2 565 ? 178.662 180.633 218.105 1.00 253.28 ? 583  LEU C CD1 1 
ATOM   10090 C CD2 . LEU B 2 565 ? 180.355 180.302 219.962 1.00 253.28 ? 583  LEU C CD2 1 
ATOM   10091 N N   . PHE B 2 566 ? 177.038 175.957 221.183 1.00 171.32 ? 584  PHE C N   1 
ATOM   10092 C CA  . PHE B 2 566 ? 176.031 175.284 222.001 1.00 171.32 ? 584  PHE C CA  1 
ATOM   10093 C C   . PHE B 2 566 ? 176.698 174.908 223.312 1.00 171.32 ? 584  PHE C C   1 
ATOM   10094 O O   . PHE B 2 566 ? 176.118 175.068 224.386 1.00 171.32 ? 584  PHE C O   1 
ATOM   10095 C CB  . PHE B 2 566 ? 175.522 173.983 221.355 1.00 238.94 ? 584  PHE C CB  1 
ATOM   10096 C CG  . PHE B 2 566 ? 174.639 174.101 220.121 1.00 238.94 ? 584  PHE C CG  1 
ATOM   10097 C CD1 . PHE B 2 566 ? 173.885 175.233 219.824 1.00 238.94 ? 584  PHE C CD1 1 
ATOM   10098 C CD2 . PHE B 2 566 ? 174.581 173.033 219.236 1.00 238.94 ? 584  PHE C CD2 1 
ATOM   10099 C CE1 . PHE B 2 566 ? 173.110 175.275 218.685 1.00 238.94 ? 584  PHE C CE1 1 
ATOM   10100 C CE2 . PHE B 2 566 ? 173.811 173.084 218.107 1.00 238.94 ? 584  PHE C CE2 1 
ATOM   10101 C CZ  . PHE B 2 566 ? 173.075 174.203 217.832 1.00 238.94 ? 584  PHE C CZ  1 
ATOM   10102 N N   . VAL B 2 567 ? 177.941 174.436 223.212 1.00 166.01 ? 585  VAL C N   1 
ATOM   10103 C CA  . VAL B 2 567 ? 178.742 174.085 224.363 1.00 166.01 ? 585  VAL C CA  1 
ATOM   10104 C C   . VAL B 2 567 ? 179.225 175.316 225.133 1.00 166.01 ? 585  VAL C C   1 
ATOM   10105 O O   . VAL B 2 567 ? 179.183 175.328 226.362 1.00 166.01 ? 585  VAL C O   1 
ATOM   10106 C CB  . VAL B 2 567 ? 179.902 173.182 223.956 1.00 240.61 ? 585  VAL C CB  1 
ATOM   10107 C CG1 . VAL B 2 567 ? 180.814 172.975 225.113 1.00 240.61 ? 585  VAL C CG1 1 
ATOM   10108 C CG2 . VAL B 2 567 ? 179.341 171.844 223.505 1.00 240.61 ? 585  VAL C CG2 1 
ATOM   10109 N N   . LEU B 2 568 ? 179.670 176.373 224.454 1.00 165.56 ? 586  LEU C N   1 
ATOM   10110 C CA  . LEU B 2 568 ? 180.119 177.544 225.192 1.00 165.56 ? 586  LEU C CA  1 
ATOM   10111 C C   . LEU B 2 568 ? 179.058 178.022 226.134 1.00 165.56 ? 586  LEU C C   1 
ATOM   10112 O O   . LEU B 2 568 ? 179.349 178.319 227.290 1.00 165.56 ? 586  LEU C O   1 
ATOM   10113 C CB  . LEU B 2 568 ? 180.435 178.699 224.254 1.00 243.17 ? 586  LEU C CB  1 
ATOM   10114 C CG  . LEU B 2 568 ? 180.892 180.034 224.895 1.00 243.17 ? 586  LEU C CG  1 
ATOM   10115 C CD1 . LEU B 2 568 ? 182.173 179.859 225.712 1.00 243.17 ? 586  LEU C CD1 1 
ATOM   10116 C CD2 . LEU B 2 568 ? 181.105 181.036 223.781 1.00 243.17 ? 586  LEU C CD2 1 
ATOM   10117 N N   . GLY B 2 569 ? 177.810 178.015 225.685 1.00 162.64 ? 587  GLY C N   1 
ATOM   10118 C CA  . GLY B 2 569 ? 176.706 178.466 226.508 1.00 162.64 ? 587  GLY C CA  1 
ATOM   10119 C C   . GLY B 2 569 ? 176.520 177.627 227.772 1.00 162.64 ? 587  GLY C C   1 
ATOM   10120 O O   . GLY B 2 569 ? 175.895 178.085 228.734 1.00 162.64 ? 587  GLY C O   1 
ATOM   10121 N N   . VAL B 2 570 ? 177.047 176.406 227.784 1.00 161.62 ? 588  VAL C N   1 
ATOM   10122 C CA  . VAL B 2 570 ? 176.956 175.546 228.936 1.00 161.62 ? 588  VAL C CA  1 
ATOM   10123 C C   . VAL B 2 570 ? 178.001 176.045 229.913 1.00 161.62 ? 588  VAL C C   1 
ATOM   10124 O O   . VAL B 2 570 ? 177.722 176.298 231.085 1.00 161.62 ? 588  VAL C O   1 
ATOM   10125 C CB  . VAL B 2 570 ? 177.233 174.070 228.544 1.00 234.24 ? 588  VAL C CB  1 
ATOM   10126 C CG1 . VAL B 2 570 ? 177.276 173.218 229.750 1.00 234.24 ? 588  VAL C CG1 1 
ATOM   10127 C CG2 . VAL B 2 570 ? 176.169 173.584 227.584 1.00 234.24 ? 588  VAL C CG2 1 
ATOM   10128 N N   . PHE B 2 571 ? 179.201 176.258 229.409 1.00 156.93 ? 589  PHE C N   1 
ATOM   10129 C CA  . PHE B 2 571 ? 180.270 176.703 230.279 1.00 156.93 ? 589  PHE C CA  1 
ATOM   10130 C C   . PHE B 2 571 ? 180.019 178.092 230.836 1.00 156.93 ? 589  PHE C C   1 
ATOM   10131 O O   . PHE B 2 571 ? 180.313 178.345 231.998 1.00 156.93 ? 589  PHE C O   1 
ATOM   10132 C CB  . PHE B 2 571 ? 181.587 176.685 229.543 1.00 218.87 ? 589  PHE C CB  1 
ATOM   10133 C CG  . PHE B 2 571 ? 182.146 175.317 229.365 1.00 218.87 ? 589  PHE C CG  1 
ATOM   10134 C CD1 . PHE B 2 571 ? 182.733 174.676 230.437 1.00 218.87 ? 589  PHE C CD1 1 
ATOM   10135 C CD2 . PHE B 2 571 ? 182.102 174.660 228.143 1.00 218.87 ? 589  PHE C CD2 1 
ATOM   10136 C CE1 . PHE B 2 571 ? 183.266 173.419 230.302 1.00 218.87 ? 589  PHE C CE1 1 
ATOM   10137 C CE2 . PHE B 2 571 ? 182.649 173.381 228.014 1.00 218.87 ? 589  PHE C CE2 1 
ATOM   10138 C CZ  . PHE B 2 571 ? 183.224 172.767 229.085 1.00 218.87 ? 589  PHE C CZ  1 
ATOM   10139 N N   . VAL B 2 572 ? 179.475 178.978 230.014 1.00 156.80 ? 590  VAL C N   1 
ATOM   10140 C CA  . VAL B 2 572 ? 179.184 180.340 230.420 1.00 156.80 ? 590  VAL C CA  1 
ATOM   10141 C C   . VAL B 2 572 ? 178.027 180.381 231.420 1.00 156.80 ? 590  VAL C C   1 
ATOM   10142 O O   . VAL B 2 572 ? 178.095 181.091 232.430 1.00 156.80 ? 590  VAL C O   1 
ATOM   10143 C CB  . VAL B 2 572 ? 178.916 181.228 229.195 1.00 227.26 ? 590  VAL C CB  1 
ATOM   10144 C CG1 . VAL B 2 572 ? 178.426 182.616 229.623 1.00 227.26 ? 590  VAL C CG1 1 
ATOM   10145 C CG2 . VAL B 2 572 ? 180.224 181.354 228.404 1.00 227.26 ? 590  VAL C CG2 1 
ATOM   10146 N N   . ARG B 2 573 ? 176.954 179.605 231.178 1.00 149.95 ? 591  ARG C N   1 
ATOM   10147 C CA  . ARG B 2 573 ? 175.830 179.578 232.106 1.00 149.95 ? 591  ARG C CA  1 
ATOM   10148 C C   . ARG B 2 573 ? 176.326 179.171 233.489 1.00 149.95 ? 591  ARG C C   1 
ATOM   10149 O O   . ARG B 2 573 ? 175.823 179.649 234.513 1.00 149.95 ? 591  ARG C O   1 
ATOM   10150 C CB  . ARG B 2 573 ? 174.745 178.614 231.642 1.00 210.59 ? 591  ARG C CB  1 
ATOM   10151 C CG  . ARG B 2 573 ? 173.515 178.495 232.562 1.00 210.59 ? 591  ARG C CG  1 
ATOM   10152 C CD  . ARG B 2 573 ? 172.739 179.781 232.623 1.00 210.59 ? 591  ARG C CD  1 
ATOM   10153 N NE  . ARG B 2 573 ? 171.601 179.699 233.512 1.00 210.59 ? 591  ARG C NE  1 
ATOM   10154 C CZ  . ARG B 2 573 ? 171.643 179.871 234.851 1.00 210.59 ? 591  ARG C CZ  1 
ATOM   10155 N NH1 . ARG B 2 573 ? 170.521 179.791 235.550 1.00 210.59 ? 591  ARG C NH1 1 
ATOM   10156 N NH2 . ARG B 2 573 ? 172.790 180.118 235.468 1.00 210.59 ? 591  ARG C NH2 1 
ATOM   10157 N N   . HIS B 2 574 ? 177.357 178.327 233.501 1.00 154.42 ? 592  HIS C N   1 
ATOM   10158 C CA  . HIS B 2 574 ? 177.994 177.814 234.689 1.00 154.42 ? 592  HIS C CA  1 
ATOM   10159 C C   . HIS B 2 574 ? 179.246 178.578 235.157 1.00 154.42 ? 592  HIS C C   1 
ATOM   10160 O O   . HIS B 2 574 ? 180.014 178.062 235.963 1.00 154.42 ? 592  HIS C O   1 
ATOM   10161 C CB  . HIS B 2 574 ? 178.251 176.322 234.493 1.00 209.99 ? 592  HIS C CB  1 
ATOM   10162 C CG  . HIS B 2 574 ? 176.978 175.549 234.569 1.00 209.99 ? 592  HIS C CG  1 
ATOM   10163 N ND1 . HIS B 2 574 ? 176.396 175.212 235.786 1.00 209.99 ? 592  HIS C ND1 1 
ATOM   10164 C CD2 . HIS B 2 574 ? 176.137 175.082 233.616 1.00 209.99 ? 592  HIS C CD2 1 
ATOM   10165 C CE1 . HIS B 2 574 ? 175.272 174.557 235.565 1.00 209.99 ? 592  HIS C CE1 1 
ATOM   10166 N NE2 . HIS B 2 574 ? 175.093 174.468 234.262 1.00 209.99 ? 592  HIS C NE2 1 
ATOM   10167 N N   . ASN B 2 575 ? 179.409 179.858 234.777 1.00 157.53 ? 593  ASN C N   1 
ATOM   10168 C CA  . ASN B 2 575 ? 180.566 180.628 235.260 1.00 157.53 ? 593  ASN C CA  1 
ATOM   10169 C C   . ASN B 2 575 ? 180.642 180.718 236.781 1.00 157.53 ? 593  ASN C C   1 
ATOM   10170 O O   . ASN B 2 575 ? 181.725 180.826 237.352 1.00 157.53 ? 593  ASN C O   1 
ATOM   10171 C CB  . ASN B 2 575 ? 180.599 182.039 234.701 1.00 212.90 ? 593  ASN C CB  1 
ATOM   10172 C CG  . ASN B 2 575 ? 181.099 182.153 233.288 1.00 212.90 ? 593  ASN C CG  1 
ATOM   10173 O OD1 . ASN B 2 575 ? 181.807 181.276 232.780 1.00 212.90 ? 593  ASN C OD1 1 
ATOM   10174 N ND2 . ASN B 2 575 ? 180.760 183.251 232.657 1.00 212.90 ? 593  ASN C ND2 1 
ATOM   10175 N N   . ALA B 2 576 ? 179.494 180.709 237.451 1.00 165.84 ? 594  ALA C N   1 
ATOM   10176 C CA  . ALA B 2 576 ? 179.445 180.787 238.906 1.00 165.84 ? 594  ALA C CA  1 
ATOM   10177 C C   . ALA B 2 576 ? 179.535 179.407 239.585 1.00 165.84 ? 594  ALA C C   1 
ATOM   10178 O O   . ALA B 2 576 ? 179.452 179.311 240.815 1.00 165.84 ? 594  ALA C O   1 
ATOM   10179 C CB  . ALA B 2 576 ? 178.168 181.474 239.342 1.00 224.04 ? 594  ALA C CB  1 
ATOM   10180 N N   . THR B 2 577 ? 179.606 178.347 238.792 1.00 168.47 ? 595  THR C N   1 
ATOM   10181 C CA  . THR B 2 577 ? 179.656 176.971 239.267 1.00 168.47 ? 595  THR C CA  1 
ATOM   10182 C C   . THR B 2 577 ? 181.157 176.603 239.384 1.00 168.47 ? 595  THR C C   1 
ATOM   10183 O O   . THR B 2 577 ? 181.939 177.044 238.538 1.00 168.47 ? 595  THR C O   1 
ATOM   10184 C CB  . THR B 2 577 ? 178.897 176.048 238.259 1.00 235.57 ? 595  THR C CB  1 
ATOM   10185 O OG1 . THR B 2 577 ? 177.522 176.461 238.151 1.00 235.57 ? 595  THR C OG1 1 
ATOM   10186 C CG2 . THR B 2 577 ? 178.880 174.591 238.654 1.00 235.57 ? 595  THR C CG2 1 
ATOM   10187 N N   . PRO B 2 578 ? 181.592 175.752 240.349 1.00 172.58 ? 596  PRO C N   1 
ATOM   10188 C CA  . PRO B 2 578 ? 182.967 175.283 240.532 1.00 172.58 ? 596  PRO C CA  1 
ATOM   10189 C C   . PRO B 2 578 ? 183.645 174.752 239.269 1.00 172.58 ? 596  PRO C C   1 
ATOM   10190 O O   . PRO B 2 578 ? 184.860 174.863 239.108 1.00 172.58 ? 596  PRO C O   1 
ATOM   10191 C CB  . PRO B 2 578 ? 182.791 174.178 241.574 1.00 294.90 ? 596  PRO C CB  1 
ATOM   10192 C CG  . PRO B 2 578 ? 181.605 174.628 242.392 1.00 294.90 ? 596  PRO C CG  1 
ATOM   10193 C CD  . PRO B 2 578 ? 180.669 175.272 241.421 1.00 294.90 ? 596  PRO C CD  1 
ATOM   10194 N N   . VAL B 2 579 ? 182.877 174.245 238.321 1.00 166.04 ? 597  VAL C N   1 
ATOM   10195 C CA  . VAL B 2 579 ? 183.471 173.730 237.104 1.00 166.04 ? 597  VAL C CA  1 
ATOM   10196 C C   . VAL B 2 579 ? 184.197 174.853 236.328 1.00 166.04 ? 597  VAL C C   1 
ATOM   10197 O O   . VAL B 2 579 ? 185.160 174.592 235.591 1.00 166.04 ? 597  VAL C O   1 
ATOM   10198 C CB  . VAL B 2 579 ? 182.368 173.075 236.241 1.00 233.82 ? 597  VAL C CB  1 
ATOM   10199 C CG1 . VAL B 2 579 ? 181.736 171.897 237.019 1.00 233.82 ? 597  VAL C CG1 1 
ATOM   10200 C CG2 . VAL B 2 579 ? 181.322 174.128 235.876 1.00 233.82 ? 597  VAL C CG2 1 
ATOM   10201 N N   . VAL B 2 580 ? 183.731 176.098 236.469 1.00 163.82 ? 598  VAL C N   1 
ATOM   10202 C CA  . VAL B 2 580 ? 184.384 177.211 235.820 1.00 163.82 ? 598  VAL C CA  1 
ATOM   10203 C C   . VAL B 2 580 ? 185.317 177.875 236.803 1.00 163.82 ? 598  VAL C C   1 
ATOM   10204 O O   . VAL B 2 580 ? 186.408 178.282 236.434 1.00 163.82 ? 598  VAL C O   1 
ATOM   10205 C CB  . VAL B 2 580 ? 183.424 178.243 235.227 1.00 230.70 ? 598  VAL C CB  1 
ATOM   10206 C CG1 . VAL B 2 580 ? 184.237 179.437 234.679 1.00 230.70 ? 598  VAL C CG1 1 
ATOM   10207 C CG2 . VAL B 2 580 ? 182.631 177.627 234.077 1.00 230.70 ? 598  VAL C CG2 1 
ATOM   10208 N N   . LYS B 2 581 ? 184.916 177.999 238.061 1.00 170.55 ? 599  LYS C N   1 
ATOM   10209 C CA  . LYS B 2 581 ? 185.781 178.681 239.028 1.00 170.55 ? 599  LYS C CA  1 
ATOM   10210 C C   . LYS B 2 581 ? 187.154 178.010 239.136 1.00 170.55 ? 599  LYS C C   1 
ATOM   10211 O O   . LYS B 2 581 ? 188.172 178.675 239.324 1.00 170.55 ? 599  LYS C O   1 
ATOM   10212 C CB  . LYS B 2 581 ? 185.130 178.732 240.398 1.00 253.61 ? 599  LYS C CB  1 
ATOM   10213 C CG  . LYS B 2 581 ? 183.953 179.669 240.485 1.00 253.61 ? 599  LYS C CG  1 
ATOM   10214 C CD  . LYS B 2 581 ? 183.310 179.621 241.856 1.00 253.61 ? 599  LYS C CD  1 
ATOM   10215 C CE  . LYS B 2 581 ? 182.244 180.679 241.979 1.00 253.61 ? 599  LYS C CE  1 
ATOM   10216 N NZ  . LYS B 2 581 ? 181.492 180.570 243.256 1.00 253.61 ? 599  LYS C NZ  1 
ATOM   10217 N N   . ALA B 2 582 ? 187.178 176.689 238.982 1.00 165.54 ? 600  ALA C N   1 
ATOM   10218 C CA  . ALA B 2 582 ? 188.383 175.879 239.032 1.00 165.54 ? 600  ALA C CA  1 
ATOM   10219 C C   . ALA B 2 582 ? 189.118 175.842 237.687 1.00 165.54 ? 600  ALA C C   1 
ATOM   10220 O O   . ALA B 2 582 ? 190.097 175.103 237.533 1.00 165.54 ? 600  ALA C O   1 
ATOM   10221 C CB  . ALA B 2 582 ? 188.027 174.463 239.432 1.00 223.64 ? 600  ALA C CB  1 
ATOM   10222 N N   . SER B 2 583 ? 188.600 176.540 236.678 1.00 159.63 ? 601  SER C N   1 
ATOM   10223 C CA  . SER B 2 583 ? 189.181 176.523 235.349 1.00 159.63 ? 601  SER C CA  1 
ATOM   10224 C C   . SER B 2 583 ? 189.808 177.854 234.930 1.00 159.63 ? 601  SER C C   1 
ATOM   10225 O O   . SER B 2 583 ? 189.378 178.951 235.305 1.00 159.63 ? 601  SER C O   1 
ATOM   10226 C CB  . SER B 2 583 ? 188.127 176.204 234.309 1.00 213.98 ? 601  SER C CB  1 
ATOM   10227 O OG  . SER B 2 583 ? 187.555 174.933 234.452 1.00 213.98 ? 601  SER C OG  1 
ATOM   10228 N N   . GLY B 2 584 ? 190.764 177.779 234.011 1.00 164.69 ? 602  GLY C N   1 
ATOM   10229 C CA  . GLY B 2 584 ? 191.329 178.980 233.403 1.00 164.69 ? 602  GLY C CA  1 
ATOM   10230 C C   . GLY B 2 584 ? 190.326 179.446 232.370 1.00 164.69 ? 602  GLY C C   1 
ATOM   10231 O O   . GLY B 2 584 ? 190.534 179.274 231.175 1.00 164.69 ? 602  GLY C O   1 
ATOM   10232 N N   . ARG B 2 585 ? 189.212 179.983 232.838 1.00 162.95 ? 603  ARG C N   1 
ATOM   10233 C CA  . ARG B 2 585 ? 188.063 180.291 232.009 1.00 162.95 ? 603  ARG C CA  1 
ATOM   10234 C C   . ARG B 2 585 ? 188.366 181.196 230.841 1.00 162.95 ? 603  ARG C C   1 
ATOM   10235 O O   . ARG B 2 585 ? 187.832 180.983 229.757 1.00 162.95 ? 603  ARG C O   1 
ATOM   10236 C CB  . ARG B 2 585 ? 186.988 180.912 232.870 1.00 238.23 ? 603  ARG C CB  1 
ATOM   10237 C CG  . ARG B 2 585 ? 187.310 182.270 233.444 1.00 238.23 ? 603  ARG C CG  1 
ATOM   10238 C CD  . ARG B 2 585 ? 186.307 182.700 234.439 1.00 238.23 ? 603  ARG C CD  1 
ATOM   10239 N NE  . ARG B 2 585 ? 186.613 184.038 234.953 1.00 238.23 ? 603  ARG C NE  1 
ATOM   10240 C CZ  . ARG B 2 585 ? 187.447 184.334 235.986 1.00 238.23 ? 603  ARG C CZ  1 
ATOM   10241 N NH1 . ARG B 2 585 ? 187.641 185.603 236.311 1.00 238.23 ? 603  ARG C NH1 1 
ATOM   10242 N NH2 . ARG B 2 585 ? 188.063 183.387 236.672 1.00 238.23 ? 603  ARG C NH2 1 
ATOM   10243 N N   . GLU B 2 586 ? 189.295 182.133 230.979 1.00 155.62 ? 604  GLU C N   1 
ATOM   10244 C CA  . GLU B 2 586 ? 189.565 182.976 229.833 1.00 155.62 ? 604  GLU C CA  1 
ATOM   10245 C C   . GLU B 2 586 ? 190.178 182.125 228.719 1.00 155.62 ? 604  GLU C C   1 
ATOM   10246 O O   . GLU B 2 586 ? 189.951 182.361 227.528 1.00 155.62 ? 604  GLU C O   1 
ATOM   10247 C CB  . GLU B 2 586 ? 190.515 184.111 230.195 1.00 208.85 ? 604  GLU C CB  1 
ATOM   10248 C CG  . GLU B 2 586 ? 190.004 185.113 231.267 1.00 208.85 ? 604  GLU C CG  1 
ATOM   10249 C CD  . GLU B 2 586 ? 190.230 184.658 232.712 1.00 208.85 ? 604  GLU C CD  1 
ATOM   10250 O OE1 . GLU B 2 586 ? 190.414 183.477 232.928 1.00 208.85 ? 604  GLU C OE1 1 
ATOM   10251 O OE2 . GLU B 2 586 ? 190.257 185.495 233.583 1.00 208.85 ? 604  GLU C OE2 1 
ATOM   10252 N N   . LEU B 2 587 ? 190.975 181.135 229.111 1.00 158.66 ? 605  LEU C N   1 
ATOM   10253 C CA  . LEU B 2 587 ? 191.648 180.250 228.193 1.00 158.66 ? 605  LEU C CA  1 
ATOM   10254 C C   . LEU B 2 587 ? 190.725 179.167 227.747 1.00 158.66 ? 605  LEU C C   1 
ATOM   10255 O O   . LEU B 2 587 ? 190.804 178.665 226.637 1.00 158.66 ? 605  LEU C O   1 
ATOM   10256 C CB  . LEU B 2 587 ? 192.894 179.693 228.845 1.00 225.51 ? 605  LEU C CB  1 
ATOM   10257 C CG  . LEU B 2 587 ? 193.979 180.660 229.088 1.00 225.51 ? 605  LEU C CG  1 
ATOM   10258 C CD1 . LEU B 2 587 ? 194.913 180.082 230.052 1.00 225.51 ? 605  LEU C CD1 1 
ATOM   10259 C CD2 . LEU B 2 587 ? 194.757 180.901 227.803 1.00 225.51 ? 605  LEU C CD2 1 
ATOM   10260 N N   . CYS B 2 588 ? 189.793 178.811 228.594 1.00 164.07 ? 606  CYS C N   1 
ATOM   10261 C CA  . CYS B 2 588 ? 188.862 177.792 228.203 1.00 164.07 ? 606  CYS C CA  1 
ATOM   10262 C C   . CYS B 2 588 ? 188.124 178.328 227.006 1.00 164.07 ? 606  CYS C C   1 
ATOM   10263 O O   . CYS B 2 588 ? 187.832 177.610 226.046 1.00 164.07 ? 606  CYS C O   1 
ATOM   10264 C CB  . CYS B 2 588 ? 187.850 177.542 229.296 1.00 218.54 ? 606  CYS C CB  1 
ATOM   10265 S SG  . CYS B 2 588 ? 188.561 176.829 230.722 1.00 218.54 ? 606  CYS C SG  1 
ATOM   10266 N N   . TYR B 2 589 ? 187.828 179.618 227.084 1.00 168.80 ? 607  TYR C N   1 
ATOM   10267 C CA  . TYR B 2 589 ? 187.126 180.328 226.063 1.00 168.80 ? 607  TYR C CA  1 
ATOM   10268 C C   . TYR B 2 589 ? 188.042 180.644 224.880 1.00 168.80 ? 607  TYR C C   1 
ATOM   10269 O O   . TYR B 2 589 ? 187.580 180.600 223.736 1.00 168.80 ? 607  TYR C O   1 
ATOM   10270 C CB  . TYR B 2 589 ? 186.477 181.555 226.704 1.00 233.94 ? 607  TYR C CB  1 
ATOM   10271 C CG  . TYR B 2 589 ? 185.408 181.172 227.808 1.00 233.94 ? 607  TYR C CG  1 
ATOM   10272 C CD1 . TYR B 2 589 ? 184.779 179.914 227.813 1.00 233.94 ? 607  TYR C CD1 1 
ATOM   10273 C CD2 . TYR B 2 589 ? 185.086 182.075 228.838 1.00 233.94 ? 607  TYR C CD2 1 
ATOM   10274 C CE1 . TYR B 2 589 ? 183.881 179.591 228.776 1.00 233.94 ? 607  TYR C CE1 1 
ATOM   10275 C CE2 . TYR B 2 589 ? 184.154 181.712 229.823 1.00 233.94 ? 607  TYR C CE2 1 
ATOM   10276 C CZ  . TYR B 2 589 ? 183.560 180.459 229.770 1.00 233.94 ? 607  TYR C CZ  1 
ATOM   10277 O OH  . TYR B 2 589 ? 182.643 180.063 230.696 1.00 233.94 ? 607  TYR C OH  1 
ATOM   10278 N N   . ILE B 2 590 ? 189.350 180.877 225.097 1.00 162.12 ? 608  ILE C N   1 
ATOM   10279 C CA  . ILE B 2 590 ? 190.187 181.160 223.937 1.00 162.12 ? 608  ILE C CA  1 
ATOM   10280 C C   . ILE B 2 590 ? 190.287 179.857 223.145 1.00 162.12 ? 608  ILE C C   1 
ATOM   10281 O O   . ILE B 2 590 ? 190.256 179.869 221.918 1.00 162.12 ? 608  ILE C O   1 
ATOM   10282 C CB  . ILE B 2 590 ? 191.628 181.666 224.286 1.00 238.93 ? 608  ILE C CB  1 
ATOM   10283 C CG1 . ILE B 2 590 ? 192.175 182.453 223.077 1.00 238.93 ? 608  ILE C CG1 1 
ATOM   10284 C CG2 . ILE B 2 590 ? 192.655 180.470 224.557 1.00 238.93 ? 608  ILE C CG2 1 
ATOM   10285 C CD1 . ILE B 2 590 ? 193.473 183.237 223.313 1.00 238.93 ? 608  ILE C CD1 1 
ATOM   10286 N N   . LEU B 2 591 ? 190.355 178.729 223.860 1.00 157.92 ? 609  LEU C N   1 
ATOM   10287 C CA  . LEU B 2 591 ? 190.409 177.411 223.267 1.00 157.92 ? 609  LEU C CA  1 
ATOM   10288 C C   . LEU B 2 591 ? 189.144 177.037 222.540 1.00 157.92 ? 609  LEU C C   1 
ATOM   10289 O O   . LEU B 2 591 ? 189.196 176.623 221.387 1.00 157.92 ? 609  LEU C O   1 
ATOM   10290 C CB  . LEU B 2 591 ? 190.766 176.405 224.377 1.00 231.95 ? 609  LEU C CB  1 
ATOM   10291 C CG  . LEU B 2 591 ? 190.686 174.889 224.086 1.00 231.95 ? 609  LEU C CG  1 
ATOM   10292 C CD1 . LEU B 2 591 ? 191.822 174.122 224.765 1.00 231.95 ? 609  LEU C CD1 1 
ATOM   10293 C CD2 . LEU B 2 591 ? 189.378 174.366 224.697 1.00 231.95 ? 609  LEU C CD2 1 
ATOM   10294 N N   . LEU B 2 592 ? 187.984 177.262 223.145 1.00 164.51 ? 610  LEU C N   1 
ATOM   10295 C CA  . LEU B 2 592 ? 186.719 176.925 222.501 1.00 164.51 ? 610  LEU C CA  1 
ATOM   10296 C C   . LEU B 2 592 ? 186.549 177.739 221.238 1.00 164.51 ? 610  LEU C C   1 
ATOM   10297 O O   . LEU B 2 592 ? 186.179 177.221 220.163 1.00 164.51 ? 610  LEU C O   1 
ATOM   10298 C CB  . LEU B 2 592 ? 185.557 177.161 223.472 1.00 241.63 ? 610  LEU C CB  1 
ATOM   10299 C CG  . LEU B 2 592 ? 184.145 176.810 222.962 1.00 241.63 ? 610  LEU C CG  1 
ATOM   10300 C CD1 . LEU B 2 592 ? 183.282 176.336 224.132 1.00 241.63 ? 610  LEU C CD1 1 
ATOM   10301 C CD2 . LEU B 2 592 ? 183.507 178.069 222.326 1.00 241.63 ? 610  LEU C CD2 1 
ATOM   10302 N N   . GLY B 2 593 ? 186.905 179.010 221.352 1.00 165.00 ? 611  GLY C N   1 
ATOM   10303 C CA  . GLY B 2 593 ? 186.791 179.959 220.289 1.00 165.00 ? 611  GLY C CA  1 
ATOM   10304 C C   . GLY B 2 593 ? 187.623 179.556 219.095 1.00 165.00 ? 611  GLY C C   1 
ATOM   10305 O O   . GLY B 2 593 ? 187.400 180.089 218.019 1.00 165.00 ? 611  GLY C O   1 
ATOM   10306 N N   . GLY B 2 594 ? 188.584 178.642 219.264 1.00 164.13 ? 612  GLY C N   1 
ATOM   10307 C CA  . GLY B 2 594 ? 189.416 178.195 218.186 1.00 164.13 ? 612  GLY C CA  1 
ATOM   10308 C C   . GLY B 2 594 ? 188.606 177.497 217.136 1.00 164.13 ? 612  GLY C C   1 
ATOM   10309 O O   . GLY B 2 594 ? 188.953 177.561 215.962 1.00 164.13 ? 612  GLY C O   1 
ATOM   10310 N N   . VAL B 2 595 ? 187.525 176.813 217.530 1.00 163.34 ? 613  VAL C N   1 
ATOM   10311 C CA  . VAL B 2 595 ? 186.692 176.124 216.561 1.00 163.34 ? 613  VAL C CA  1 
ATOM   10312 C C   . VAL B 2 595 ? 185.816 177.142 215.902 1.00 163.34 ? 613  VAL C C   1 
ATOM   10313 O O   . VAL B 2 595 ? 185.505 177.039 214.714 1.00 163.34 ? 613  VAL C O   1 
ATOM   10314 C CB  . VAL B 2 595 ? 185.886 174.982 217.146 1.00 236.74 ? 613  VAL C CB  1 
ATOM   10315 C CG1 . VAL B 2 595 ? 184.937 174.401 216.065 1.00 236.74 ? 613  VAL C CG1 1 
ATOM   10316 C CG2 . VAL B 2 595 ? 186.824 173.953 217.562 1.00 236.74 ? 613  VAL C CG2 1 
ATOM   10317 N N   . PHE B 2 596 ? 185.334 178.085 216.686 1.00 164.14 ? 614  PHE C N   1 
ATOM   10318 C CA  . PHE B 2 596 ? 184.522 179.107 216.068 1.00 164.14 ? 614  PHE C CA  1 
ATOM   10319 C C   . PHE B 2 596 ? 185.404 179.822 215.035 1.00 164.14 ? 614  PHE C C   1 
ATOM   10320 O O   . PHE B 2 596 ? 184.951 180.180 213.943 1.00 164.14 ? 614  PHE C O   1 
ATOM   10321 C CB  . PHE B 2 596 ? 183.909 180.071 217.048 1.00 228.93 ? 614  PHE C CB  1 
ATOM   10322 C CG  . PHE B 2 596 ? 183.001 180.944 216.334 1.00 228.93 ? 614  PHE C CG  1 
ATOM   10323 C CD1 . PHE B 2 596 ? 181.772 180.460 215.925 1.00 228.93 ? 614  PHE C CD1 1 
ATOM   10324 C CD2 . PHE B 2 596 ? 183.343 182.234 216.029 1.00 228.93 ? 614  PHE C CD2 1 
ATOM   10325 C CE1 . PHE B 2 596 ? 180.913 181.257 215.220 1.00 228.93 ? 614  PHE C CE1 1 
ATOM   10326 C CE2 . PHE B 2 596 ? 182.475 183.030 215.330 1.00 228.93 ? 614  PHE C CE2 1 
ATOM   10327 C CZ  . PHE B 2 596 ? 181.262 182.537 214.923 1.00 228.93 ? 614  PHE C CZ  1 
ATOM   10328 N N   . LEU B 2 597 ? 186.662 180.080 215.403 1.00 162.02 ? 615  LEU C N   1 
ATOM   10329 C CA  . LEU B 2 597 ? 187.592 180.670 214.480 1.00 162.02 ? 615  LEU C CA  1 
ATOM   10330 C C   . LEU B 2 597 ? 187.834 179.713 213.336 1.00 162.02 ? 615  LEU C C   1 
ATOM   10331 O O   . LEU B 2 597 ? 187.862 180.152 212.202 1.00 162.02 ? 615  LEU C O   1 
ATOM   10332 C CB  . LEU B 2 597 ? 188.929 181.003 215.145 1.00 237.97 ? 615  LEU C CB  1 
ATOM   10333 C CG  . LEU B 2 597 ? 188.954 182.146 216.158 1.00 237.97 ? 615  LEU C CG  1 
ATOM   10334 C CD1 . LEU B 2 597 ? 190.315 182.143 216.881 1.00 237.97 ? 615  LEU C CD1 1 
ATOM   10335 C CD2 . LEU B 2 597 ? 188.751 183.469 215.434 1.00 237.97 ? 615  LEU C CD2 1 
ATOM   10336 N N   . CYS B 2 598 ? 187.907 178.395 213.565 1.00 162.84 ? 616  CYS C N   1 
ATOM   10337 C CA  . CYS B 2 598 ? 188.115 177.478 212.448 1.00 162.84 ? 616  CYS C CA  1 
ATOM   10338 C C   . CYS B 2 598 ? 187.021 177.705 211.422 1.00 162.84 ? 616  CYS C C   1 
ATOM   10339 O O   . CYS B 2 598 ? 187.290 177.746 210.218 1.00 162.84 ? 616  CYS C O   1 
ATOM   10340 C CB  . CYS B 2 598 ? 188.077 176.019 212.882 1.00 216.90 ? 616  CYS C CB  1 
ATOM   10341 S SG  . CYS B 2 598 ? 189.472 175.470 213.900 1.00 216.90 ? 616  CYS C SG  1 
ATOM   10342 N N   . TYR B 2 599 ? 185.789 177.869 211.898 1.00 169.20 ? 617  TYR C N   1 
ATOM   10343 C CA  . TYR B 2 599 ? 184.667 178.207 211.034 1.00 169.20 ? 617  TYR C CA  1 
ATOM   10344 C C   . TYR B 2 599 ? 184.900 179.498 210.273 1.00 169.20 ? 617  TYR C C   1 
ATOM   10345 O O   . TYR B 2 599 ? 184.756 179.552 209.051 1.00 169.20 ? 617  TYR C O   1 
ATOM   10346 C CB  . TYR B 2 599 ? 183.394 178.288 211.866 1.00 234.50 ? 617  TYR C CB  1 
ATOM   10347 C CG  . TYR B 2 599 ? 182.265 179.059 211.242 1.00 234.50 ? 617  TYR C CG  1 
ATOM   10348 C CD1 . TYR B 2 599 ? 181.452 178.542 210.271 1.00 234.50 ? 617  TYR C CD1 1 
ATOM   10349 C CD2 . TYR B 2 599 ? 182.048 180.338 211.709 1.00 234.50 ? 617  TYR C CD2 1 
ATOM   10350 C CE1 . TYR B 2 599 ? 180.429 179.284 209.757 1.00 234.50 ? 617  TYR C CE1 1 
ATOM   10351 C CE2 . TYR B 2 599 ? 181.036 181.088 211.198 1.00 234.50 ? 617  TYR C CE2 1 
ATOM   10352 C CZ  . TYR B 2 599 ? 180.222 180.564 210.216 1.00 234.50 ? 617  TYR C CZ  1 
ATOM   10353 O OH  . TYR B 2 599 ? 179.199 181.321 209.698 1.00 234.50 ? 617  TYR C OH  1 
ATOM   10354 N N   . CYS B 2 600 ? 185.281 180.538 210.984 1.00 173.00 ? 618  CYS C N   1 
ATOM   10355 C CA  . CYS B 2 600 ? 185.478 181.826 210.356 1.00 173.00 ? 618  CYS C CA  1 
ATOM   10356 C C   . CYS B 2 600 ? 186.587 181.769 209.307 1.00 173.00 ? 618  CYS C C   1 
ATOM   10357 O O   . CYS B 2 600 ? 186.461 182.320 208.202 1.00 173.00 ? 618  CYS C O   1 
ATOM   10358 C CB  . CYS B 2 600 ? 185.888 182.832 211.418 1.00 231.90 ? 618  CYS C CB  1 
ATOM   10359 S SG  . CYS B 2 600 ? 184.602 183.164 212.611 1.00 231.90 ? 618  CYS C SG  1 
ATOM   10360 N N   . MET B 2 601 ? 187.658 181.071 209.667 1.00 167.49 ? 619  MET C N   1 
ATOM   10361 C CA  . MET B 2 601 ? 188.837 180.907 208.862 1.00 167.49 ? 619  MET C CA  1 
ATOM   10362 C C   . MET B 2 601 ? 188.506 180.091 207.641 1.00 167.49 ? 619  MET C C   1 
ATOM   10363 O O   . MET B 2 601 ? 188.958 180.421 206.558 1.00 167.49 ? 619  MET C O   1 
ATOM   10364 C CB  . MET B 2 601 ? 189.948 180.291 209.702 1.00 239.34 ? 619  MET C CB  1 
ATOM   10365 C CG  . MET B 2 601 ? 190.479 181.253 210.792 1.00 239.34 ? 619  MET C CG  1 
ATOM   10366 S SD  . MET B 2 601 ? 191.941 180.687 211.673 1.00 239.34 ? 619  MET C SD  1 
ATOM   10367 C CE  . MET B 2 601 ? 191.475 179.280 212.659 1.00 239.34 ? 619  MET C CE  1 
ATOM   10368 N N   . THR B 2 602 ? 187.620 179.112 207.786 1.00 168.60 ? 620  THR C N   1 
ATOM   10369 C CA  . THR B 2 602 ? 187.201 178.299 206.666 1.00 168.60 ? 620  THR C CA  1 
ATOM   10370 C C   . THR B 2 602 ? 186.600 179.137 205.592 1.00 168.60 ? 620  THR C C   1 
ATOM   10371 O O   . THR B 2 602 ? 186.878 178.943 204.413 1.00 168.60 ? 620  THR C O   1 
ATOM   10372 C CB  . THR B 2 602 ? 186.188 177.231 207.084 1.00 235.75 ? 620  THR C CB  1 
ATOM   10373 O OG1 . THR B 2 602 ? 186.832 176.313 207.976 1.00 235.75 ? 620  THR C OG1 1 
ATOM   10374 C CG2 . THR B 2 602 ? 185.641 176.533 205.847 1.00 235.75 ? 620  THR C CG2 1 
ATOM   10375 N N   . PHE B 2 603 ? 185.767 180.079 205.974 1.00 174.45 ? 621  PHE C N   1 
ATOM   10376 C CA  . PHE B 2 603 ? 185.188 180.906 204.951 1.00 174.45 ? 621  PHE C CA  1 
ATOM   10377 C C   . PHE B 2 603 ? 186.266 181.835 204.360 1.00 174.45 ? 621  PHE C C   1 
ATOM   10378 O O   . PHE B 2 603 ? 186.316 182.034 203.149 1.00 174.45 ? 621  PHE C O   1 
ATOM   10379 C CB  . PHE B 2 603 ? 183.926 181.556 205.484 1.00 243.31 ? 621  PHE C CB  1 
ATOM   10380 C CG  . PHE B 2 603 ? 182.833 180.475 205.509 1.00 243.31 ? 621  PHE C CG  1 
ATOM   10381 C CD1 . PHE B 2 603 ? 182.058 180.203 204.387 1.00 243.31 ? 621  PHE C CD1 1 
ATOM   10382 C CD2 . PHE B 2 603 ? 182.620 179.705 206.632 1.00 243.31 ? 621  PHE C CD2 1 
ATOM   10383 C CE1 . PHE B 2 603 ? 181.112 179.185 204.405 1.00 243.31 ? 621  PHE C CE1 1 
ATOM   10384 C CE2 . PHE B 2 603 ? 181.690 178.695 206.641 1.00 243.31 ? 621  PHE C CE2 1 
ATOM   10385 C CZ  . PHE B 2 603 ? 180.942 178.433 205.545 1.00 243.31 ? 621  PHE C CZ  1 
ATOM   10386 N N   . ILE B 2 604 ? 187.206 182.310 205.173 1.00 179.97 ? 622  ILE C N   1 
ATOM   10387 C CA  . ILE B 2 604 ? 188.295 183.134 204.639 1.00 179.97 ? 622  ILE C CA  1 
ATOM   10388 C C   . ILE B 2 604 ? 189.129 182.313 203.645 1.00 179.97 ? 622  ILE C C   1 
ATOM   10389 O O   . ILE B 2 604 ? 189.500 182.801 202.580 1.00 179.97 ? 622  ILE C O   1 
ATOM   10390 C CB  . ILE B 2 604 ? 189.204 183.722 205.737 1.00 265.23 ? 622  ILE C CB  1 
ATOM   10391 C CG1 . ILE B 2 604 ? 188.400 184.752 206.553 1.00 265.23 ? 622  ILE C CG1 1 
ATOM   10392 C CG2 . ILE B 2 604 ? 190.466 184.391 205.091 1.00 265.23 ? 622  ILE C CG2 1 
ATOM   10393 C CD1 . ILE B 2 604 ? 189.061 185.197 207.842 1.00 265.23 ? 622  ILE C CD1 1 
ATOM   10394 N N   . PHE B 2 605 ? 189.356 181.041 203.957 1.00 176.74 ? 623  PHE C N   1 
ATOM   10395 C CA  . PHE B 2 605 ? 190.156 180.112 203.166 1.00 176.74 ? 623  PHE C CA  1 
ATOM   10396 C C   . PHE B 2 605 ? 189.602 179.926 201.764 1.00 176.74 ? 623  PHE C C   1 
ATOM   10397 O O   . PHE B 2 605 ? 190.300 179.384 200.903 1.00 176.74 ? 623  PHE C O   1 
ATOM   10398 C CB  . PHE B 2 605 ? 190.167 178.692 203.760 1.00 246.50 ? 623  PHE C CB  1 
ATOM   10399 C CG  . PHE B 2 605 ? 190.863 178.432 205.093 1.00 246.50 ? 623  PHE C CG  1 
ATOM   10400 C CD1 . PHE B 2 605 ? 191.712 179.326 205.714 1.00 246.50 ? 623  PHE C CD1 1 
ATOM   10401 C CD2 . PHE B 2 605 ? 190.649 177.216 205.728 1.00 246.50 ? 623  PHE C CD2 1 
ATOM   10402 C CE1 . PHE B 2 605 ? 192.313 178.992 206.932 1.00 246.50 ? 623  PHE C CE1 1 
ATOM   10403 C CE2 . PHE B 2 605 ? 191.225 176.893 206.909 1.00 246.50 ? 623  PHE C CE2 1 
ATOM   10404 C CZ  . PHE B 2 605 ? 192.064 177.781 207.520 1.00 246.50 ? 623  PHE C CZ  1 
ATOM   10405 N N   . ILE B 2 606 ? 188.332 180.264 201.540 1.00 192.95 ? 624  ILE C N   1 
ATOM   10406 C CA  . ILE B 2 606 ? 187.729 180.061 200.243 1.00 192.95 ? 624  ILE C CA  1 
ATOM   10407 C C   . ILE B 2 606 ? 187.407 181.399 199.576 1.00 192.95 ? 624  ILE C C   1 
ATOM   10408 O O   . ILE B 2 606 ? 186.709 181.445 198.561 1.00 192.95 ? 624  ILE C O   1 
ATOM   10409 C CB  . ILE B 2 606 ? 186.483 179.161 200.368 1.00 284.36 ? 624  ILE C CB  1 
ATOM   10410 C CG1 . ILE B 2 606 ? 185.421 179.823 201.241 1.00 284.36 ? 624  ILE C CG1 1 
ATOM   10411 C CG2 . ILE B 2 606 ? 186.932 177.845 201.015 1.00 284.36 ? 624  ILE C CG2 1 
ATOM   10412 C CD1 . ILE B 2 606 ? 184.051 179.165 201.241 1.00 284.36 ? 624  ILE C CD1 1 
ATOM   10413 N N   . ALA B 2 607 ? 187.921 182.485 200.155 1.00 202.79 ? 625  ALA C N   1 
ATOM   10414 C CA  . ALA B 2 607 ? 187.745 183.834 199.644 1.00 202.79 ? 625  ALA C CA  1 
ATOM   10415 C C   . ALA B 2 607 ? 188.495 183.964 198.340 1.00 202.79 ? 625  ALA C C   1 
ATOM   10416 O O   . ALA B 2 607 ? 189.518 183.307 198.154 1.00 202.79 ? 625  ALA C O   1 
ATOM   10417 C CB  . ALA B 2 607 ? 188.260 184.856 200.645 1.00 273.96 ? 625  ALA C CB  1 
ATOM   10418 N N   . LYS B 2 608 ? 188.030 184.809 197.420 1.00 201.66 ? 626  LYS C N   1 
ATOM   10419 C CA  . LYS B 2 608 ? 188.805 184.959 196.199 1.00 201.66 ? 626  LYS C CA  1 
ATOM   10420 C C   . LYS B 2 608 ? 190.231 185.328 196.615 1.00 201.66 ? 626  LYS C C   1 
ATOM   10421 O O   . LYS B 2 608 ? 190.396 186.271 197.385 1.00 201.66 ? 626  LYS C O   1 
ATOM   10422 C CB  . LYS B 2 608 ? 188.228 186.030 195.287 1.00 299.87 ? 626  LYS C CB  1 
ATOM   10423 C CG  . LYS B 2 608 ? 188.965 186.145 193.960 1.00 299.87 ? 626  LYS C CG  1 
ATOM   10424 C CD  . LYS B 2 608 ? 188.311 187.151 193.034 1.00 299.87 ? 626  LYS C CD  1 
ATOM   10425 C CE  . LYS B 2 608 ? 189.054 187.234 191.705 1.00 299.87 ? 626  LYS C CE  1 
ATOM   10426 N NZ  . LYS B 2 608 ? 188.430 188.222 190.778 1.00 299.87 ? 626  LYS C NZ  1 
ATOM   10427 N N   . PRO B 2 609 ? 191.268 184.596 196.169 1.00 200.08 ? 627  PRO C N   1 
ATOM   10428 C CA  . PRO B 2 609 ? 192.661 184.809 196.510 1.00 200.08 ? 627  PRO C CA  1 
ATOM   10429 C C   . PRO B 2 609 ? 193.306 186.160 196.228 1.00 200.08 ? 627  PRO C C   1 
ATOM   10430 O O   . PRO B 2 609 ? 193.400 186.633 195.094 1.00 200.08 ? 627  PRO C O   1 
ATOM   10431 C CB  . PRO B 2 609 ? 193.335 183.759 195.617 1.00 341.89 ? 627  PRO C CB  1 
ATOM   10432 C CG  . PRO B 2 609 ? 192.353 182.692 195.444 1.00 341.89 ? 627  PRO C CG  1 
ATOM   10433 C CD  . PRO B 2 609 ? 191.038 183.389 195.360 1.00 341.89 ? 627  PRO C CD  1 
ATOM   10434 N N   . SER B 2 610 ? 193.944 186.649 197.277 1.00 196.63 ? 628  SER C N   1 
ATOM   10435 C CA  . SER B 2 610 ? 194.738 187.860 197.338 1.00 196.63 ? 628  SER C CA  1 
ATOM   10436 C C   . SER B 2 610 ? 195.631 187.680 198.559 1.00 196.63 ? 628  SER C C   1 
ATOM   10437 O O   . SER B 2 610 ? 195.381 186.783 199.383 1.00 196.63 ? 628  SER C O   1 
ATOM   10438 C CB  . SER B 2 610 ? 193.864 189.089 197.430 1.00 261.90 ? 628  SER C CB  1 
ATOM   10439 O OG  . SER B 2 610 ? 193.228 189.151 198.654 1.00 261.90 ? 628  SER C OG  1 
ATOM   10440 N N   . THR B 2 611 ? 196.616 188.551 198.740 1.00 203.54 ? 629  THR C N   1 
ATOM   10441 C CA  . THR B 2 611 ? 197.488 188.435 199.899 1.00 203.54 ? 629  THR C CA  1 
ATOM   10442 C C   . THR B 2 611 ? 196.785 188.814 201.185 1.00 203.54 ? 629  THR C C   1 
ATOM   10443 O O   . THR B 2 611 ? 197.163 188.380 202.286 1.00 203.54 ? 629  THR C O   1 
ATOM   10444 C CB  . THR B 2 611 ? 198.740 189.281 199.705 1.00 278.63 ? 629  THR C CB  1 
ATOM   10445 O OG1 . THR B 2 611 ? 198.357 190.639 199.480 1.00 278.63 ? 629  THR C OG1 1 
ATOM   10446 C CG2 . THR B 2 611 ? 199.511 188.751 198.531 1.00 278.63 ? 629  THR C CG2 1 
ATOM   10447 N N   . ALA B 2 612 ? 195.677 189.539 201.016 1.00 206.93 ? 630  ALA C N   1 
ATOM   10448 C CA  . ALA B 2 612 ? 194.803 190.015 202.075 1.00 206.93 ? 630  ALA C CA  1 
ATOM   10449 C C   . ALA B 2 612 ? 194.216 188.860 202.850 1.00 206.93 ? 630  ALA C C   1 
ATOM   10450 O O   . ALA B 2 612 ? 193.801 189.020 203.997 1.00 206.93 ? 630  ALA C O   1 
ATOM   10451 C CB  . ALA B 2 612 ? 193.668 190.848 201.502 1.00 279.55 ? 630  ALA C CB  1 
ATOM   10452 N N   . VAL B 2 613 ? 194.077 187.723 202.182 1.00 204.22 ? 631  VAL C N   1 
ATOM   10453 C CA  . VAL B 2 613 ? 193.504 186.553 202.806 1.00 204.22 ? 631  VAL C CA  1 
ATOM   10454 C C   . VAL B 2 613 ? 194.454 185.342 202.946 1.00 204.22 ? 631  VAL C C   1 
ATOM   10455 O O   . VAL B 2 613 ? 194.281 184.576 203.904 1.00 204.22 ? 631  VAL C O   1 
ATOM   10456 C CB  . VAL B 2 613 ? 192.171 186.184 202.104 1.00 295.99 ? 631  VAL C CB  1 
ATOM   10457 C CG1 . VAL B 2 613 ? 191.165 187.319 202.318 1.00 295.99 ? 631  VAL C CG1 1 
ATOM   10458 C CG2 . VAL B 2 613 ? 192.386 185.971 200.591 1.00 295.99 ? 631  VAL C CG2 1 
ATOM   10459 N N   . CYS B 2 614 ? 195.455 185.129 202.012 1.00 207.58 ? 632  CYS C N   1 
ATOM   10460 C CA  . CYS B 2 614 ? 196.315 183.946 202.080 1.00 207.58 ? 632  CYS C CA  1 
ATOM   10461 C C   . CYS B 2 614 ? 197.300 184.044 203.247 1.00 207.58 ? 632  CYS C C   1 
ATOM   10462 O O   . CYS B 2 614 ? 197.733 183.018 203.792 1.00 207.58 ? 632  CYS C O   1 
ATOM   10463 C CB  . CYS B 2 614 ? 197.117 183.758 200.770 1.00 268.99 ? 632  CYS C CB  1 
ATOM   10464 S SG  . CYS B 2 614 ? 198.474 184.929 200.518 1.00 268.99 ? 632  CYS C SG  1 
ATOM   10465 N N   . THR B 2 615 ? 197.636 185.261 203.670 1.00 206.42 ? 633  THR C N   1 
ATOM   10466 C CA  . THR B 2 615 ? 198.553 185.357 204.780 1.00 206.42 ? 633  THR C CA  1 
ATOM   10467 C C   . THR B 2 615 ? 197.817 184.852 206.005 1.00 206.42 ? 633  THR C C   1 
ATOM   10468 O O   . THR B 2 615 ? 198.354 184.070 206.792 1.00 206.42 ? 633  THR C O   1 
ATOM   10469 C CB  . THR B 2 615 ? 199.063 186.789 205.006 1.00 282.57 ? 633  THR C CB  1 
ATOM   10470 O OG1 . THR B 2 615 ? 199.721 187.270 203.819 1.00 282.57 ? 633  THR C OG1 1 
ATOM   10471 C CG2 . THR B 2 615 ? 200.102 186.747 206.124 1.00 282.57 ? 633  THR C CG2 1 
ATOM   10472 N N   . LEU B 2 616 ? 196.553 185.270 206.129 1.00 201.75 ? 634  LEU C N   1 
ATOM   10473 C CA  . LEU B 2 616 ? 195.715 184.894 207.248 1.00 201.75 ? 634  LEU C CA  1 
ATOM   10474 C C   . LEU B 2 616 ? 195.495 183.408 207.214 1.00 201.75 ? 634  LEU C C   1 
ATOM   10475 O O   . LEU B 2 616 ? 195.486 182.754 208.255 1.00 201.75 ? 634  LEU C O   1 
ATOM   10476 C CB  . LEU B 2 616 ? 194.335 185.548 207.146 1.00 286.76 ? 634  LEU C CB  1 
ATOM   10477 C CG  . LEU B 2 616 ? 194.250 187.054 207.266 1.00 286.76 ? 634  LEU C CG  1 
ATOM   10478 C CD1 . LEU B 2 616 ? 192.805 187.471 206.957 1.00 286.76 ? 634  LEU C CD1 1 
ATOM   10479 C CD2 . LEU B 2 616 ? 194.673 187.502 208.661 1.00 286.76 ? 634  LEU C CD2 1 
ATOM   10480 N N   . ARG B 2 617 ? 195.330 182.869 206.011 1.00 198.62 ? 635  ARG C N   1 
ATOM   10481 C CA  . ARG B 2 617 ? 195.125 181.453 205.835 1.00 198.62 ? 635  ARG C CA  1 
ATOM   10482 C C   . ARG B 2 617 ? 196.253 180.659 206.418 1.00 198.62 ? 635  ARG C C   1 
ATOM   10483 O O   . ARG B 2 617 ? 196.032 179.732 207.189 1.00 198.62 ? 635  ARG C O   1 
ATOM   10484 C CB  . ARG B 2 617 ? 195.058 181.132 204.370 1.00 290.38 ? 635  ARG C CB  1 
ATOM   10485 C CG  . ARG B 2 617 ? 194.956 179.692 204.004 1.00 290.38 ? 635  ARG C CG  1 
ATOM   10486 C CD  . ARG B 2 617 ? 195.200 179.546 202.582 1.00 290.38 ? 635  ARG C CD  1 
ATOM   10487 N NE  . ARG B 2 617 ? 196.549 180.033 202.236 1.00 290.38 ? 635  ARG C NE  1 
ATOM   10488 C CZ  . ARG B 2 617 ? 197.697 179.366 202.407 1.00 290.38 ? 635  ARG C CZ  1 
ATOM   10489 N NH1 . ARG B 2 617 ? 198.825 179.964 202.075 1.00 290.38 ? 635  ARG C NH1 1 
ATOM   10490 N NH2 . ARG B 2 617 ? 197.706 178.143 202.891 1.00 290.38 ? 635  ARG C NH2 1 
ATOM   10491 N N   . ARG B 2 618 ? 197.474 181.034 206.087 1.00 187.01 ? 636  ARG C N   1 
ATOM   10492 C CA  . ARG B 2 618 ? 198.595 180.301 206.620 1.00 187.01 ? 636  ARG C CA  1 
ATOM   10493 C C   . ARG B 2 618 ? 198.696 180.497 208.136 1.00 187.01 ? 636  ARG C C   1 
ATOM   10494 O O   . ARG B 2 618 ? 198.909 179.554 208.888 1.00 187.01 ? 636  ARG C O   1 
ATOM   10495 C CB  . ARG B 2 618 ? 199.862 180.725 205.899 1.00 262.64 ? 636  ARG C CB  1 
ATOM   10496 C CG  . ARG B 2 618 ? 201.166 180.080 206.359 1.00 262.64 ? 636  ARG C CG  1 
ATOM   10497 C CD  . ARG B 2 618 ? 201.219 178.584 206.219 1.00 262.64 ? 636  ARG C CD  1 
ATOM   10498 N NE  . ARG B 2 618 ? 201.243 178.126 204.834 1.00 262.64 ? 636  ARG C NE  1 
ATOM   10499 C CZ  . ARG B 2 618 ? 201.084 176.841 204.440 1.00 262.64 ? 636  ARG C CZ  1 
ATOM   10500 N NH1 . ARG B 2 618 ? 201.141 176.548 203.153 1.00 262.64 ? 636  ARG C NH1 1 
ATOM   10501 N NH2 . ARG B 2 618 ? 200.879 175.885 205.321 1.00 262.64 ? 636  ARG C NH2 1 
ATOM   10502 N N   . LEU B 2 619 ? 198.444 181.706 208.614 1.00 187.93 ? 637  LEU C N   1 
ATOM   10503 C CA  . LEU B 2 619 ? 198.508 181.990 210.041 1.00 187.93 ? 637  LEU C CA  1 
ATOM   10504 C C   . LEU B 2 619 ? 197.439 181.270 210.813 1.00 187.93 ? 637  LEU C C   1 
ATOM   10505 O O   . LEU B 2 619 ? 197.624 180.901 211.981 1.00 187.93 ? 637  LEU C O   1 
ATOM   10506 C CB  . LEU B 2 619 ? 198.368 183.483 210.247 1.00 276.03 ? 637  LEU C CB  1 
ATOM   10507 C CG  . LEU B 2 619 ? 199.536 184.280 209.788 1.00 276.03 ? 637  LEU C CG  1 
ATOM   10508 C CD1 . LEU B 2 619 ? 199.156 185.748 209.752 1.00 276.03 ? 637  LEU C CD1 1 
ATOM   10509 C CD2 . LEU B 2 619 ? 200.705 184.032 210.765 1.00 276.03 ? 637  LEU C CD2 1 
ATOM   10510 N N   . GLY B 2 620 ? 196.334 181.018 210.149 1.00 189.33 ? 638  GLY C N   1 
ATOM   10511 C CA  . GLY B 2 620 ? 195.189 180.347 210.689 1.00 189.33 ? 638  GLY C CA  1 
ATOM   10512 C C   . GLY B 2 620 ? 195.477 178.901 211.040 1.00 189.33 ? 638  GLY C C   1 
ATOM   10513 O O   . GLY B 2 620 ? 194.733 178.272 211.802 1.00 189.33 ? 638  GLY C O   1 
ATOM   10514 N N   . LEU B 2 621 ? 196.581 178.373 210.516 1.00 178.81 ? 639  LEU C N   1 
ATOM   10515 C CA  . LEU B 2 621 ? 196.951 177.003 210.748 1.00 178.81 ? 639  LEU C CA  1 
ATOM   10516 C C   . LEU B 2 621 ? 197.821 176.929 211.987 1.00 178.81 ? 639  LEU C C   1 
ATOM   10517 O O   . LEU B 2 621 ? 198.192 175.850 212.452 1.00 178.81 ? 639  LEU C O   1 
ATOM   10518 C CB  . LEU B 2 621 ? 197.640 176.489 209.493 1.00 254.15 ? 639  LEU C CB  1 
ATOM   10519 C CG  . LEU B 2 621 ? 196.779 176.549 208.215 1.00 254.15 ? 639  LEU C CG  1 
ATOM   10520 C CD1 . LEU B 2 621 ? 197.642 176.145 207.038 1.00 254.15 ? 639  LEU C CD1 1 
ATOM   10521 C CD2 . LEU B 2 621 ? 195.530 175.663 208.354 1.00 254.15 ? 639  LEU C CD2 1 
ATOM   10522 N N   . GLY B 2 622 ? 198.102 178.099 212.533 1.00 174.42 ? 640  GLY C N   1 
ATOM   10523 C CA  . GLY B 2 622 ? 198.802 178.304 213.770 1.00 174.42 ? 640  GLY C CA  1 
ATOM   10524 C C   . GLY B 2 622 ? 197.683 178.580 214.753 1.00 174.42 ? 640  GLY C C   1 
ATOM   10525 O O   . GLY B 2 622 ? 197.472 177.816 215.704 1.00 174.42 ? 640  GLY C O   1 
ATOM   10526 N N   . THR B 2 623 ? 196.922 179.636 214.443 1.00 172.51 ? 641  THR C N   1 
ATOM   10527 C CA  . THR B 2 623 ? 195.823 180.168 215.238 1.00 172.51 ? 641  THR C CA  1 
ATOM   10528 C C   . THR B 2 623 ? 194.907 179.114 215.787 1.00 172.51 ? 641  THR C C   1 
ATOM   10529 O O   . THR B 2 623 ? 194.579 179.120 216.973 1.00 172.51 ? 641  THR C O   1 
ATOM   10530 C CB  . THR B 2 623 ? 194.922 181.084 214.398 1.00 241.22 ? 641  THR C CB  1 
ATOM   10531 O OG1 . THR B 2 623 ? 195.684 182.171 213.852 1.00 241.22 ? 641  THR C OG1 1 
ATOM   10532 C CG2 . THR B 2 623 ? 193.809 181.649 215.265 1.00 241.22 ? 641  THR C CG2 1 
ATOM   10533 N N   . ALA B 2 624 ? 194.483 178.166 214.964 1.00 167.51 ? 642  ALA C N   1 
ATOM   10534 C CA  . ALA B 2 624 ? 193.516 177.220 215.476 1.00 167.51 ? 642  ALA C CA  1 
ATOM   10535 C C   . ALA B 2 624 ? 194.004 176.530 216.737 1.00 167.51 ? 642  ALA C C   1 
ATOM   10536 O O   . ALA B 2 624 ? 193.208 176.303 217.642 1.00 167.51 ? 642  ALA C O   1 
ATOM   10537 C CB  . ALA B 2 624 ? 193.219 176.172 214.422 1.00 226.30 ? 642  ALA C CB  1 
ATOM   10538 N N   . PHE B 2 625 ? 195.291 176.192 216.821 1.00 167.39 ? 643  PHE C N   1 
ATOM   10539 C CA  . PHE B 2 625 ? 195.791 175.494 217.993 1.00 167.39 ? 643  PHE C CA  1 
ATOM   10540 C C   . PHE B 2 625 ? 196.619 176.356 218.887 1.00 167.39 ? 643  PHE C C   1 
ATOM   10541 O O   . PHE B 2 625 ? 196.810 176.041 220.080 1.00 167.39 ? 643  PHE C O   1 
ATOM   10542 C CB  . PHE B 2 625 ? 196.440 174.183 217.610 1.00 233.46 ? 643  PHE C CB  1 
ATOM   10543 C CG  . PHE B 2 625 ? 195.404 173.190 217.302 1.00 233.46 ? 643  PHE C CG  1 
ATOM   10544 C CD1 . PHE B 2 625 ? 194.830 173.083 216.055 1.00 233.46 ? 643  PHE C CD1 1 
ATOM   10545 C CD2 . PHE B 2 625 ? 194.982 172.339 218.303 1.00 233.46 ? 643  PHE C CD2 1 
ATOM   10546 C CE1 . PHE B 2 625 ? 193.828 172.150 215.830 1.00 233.46 ? 643  PHE C CE1 1 
ATOM   10547 C CE2 . PHE B 2 625 ? 194.010 171.421 218.082 1.00 233.46 ? 643  PHE C CE2 1 
ATOM   10548 C CZ  . PHE B 2 625 ? 193.422 171.321 216.854 1.00 233.46 ? 643  PHE C CZ  1 
ATOM   10549 N N   . SER B 2 626 ? 196.942 177.563 218.401 1.00 171.73 ? 644  SER C N   1 
ATOM   10550 C CA  . SER B 2 626 ? 197.639 178.480 219.261 1.00 171.73 ? 644  SER C CA  1 
ATOM   10551 C C   . SER B 2 626 ? 196.639 178.762 220.365 1.00 171.73 ? 644  SER C C   1 
ATOM   10552 O O   . SER B 2 626 ? 197.039 179.005 221.495 1.00 171.73 ? 644  SER C O   1 
ATOM   10553 C CB  . SER B 2 626 ? 198.027 179.770 218.565 1.00 230.19 ? 644  SER C CB  1 
ATOM   10554 O OG  . SER B 2 626 ? 196.913 180.566 218.352 1.00 230.19 ? 644  SER C OG  1 
ATOM   10555 N N   . VAL B 2 627 ? 195.334 178.626 220.056 1.00 166.13 ? 645  VAL C N   1 
ATOM   10556 C CA  . VAL B 2 627 ? 194.326 178.734 221.078 1.00 166.13 ? 645  VAL C CA  1 
ATOM   10557 C C   . VAL B 2 627 ? 193.791 177.339 221.507 1.00 166.13 ? 645  VAL C C   1 
ATOM   10558 O O   . VAL B 2 627 ? 193.684 177.066 222.710 1.00 166.13 ? 645  VAL C O   1 
ATOM   10559 C CB  . VAL B 2 627 ? 193.200 179.644 220.595 1.00 233.95 ? 645  VAL C CB  1 
ATOM   10560 C CG1 . VAL B 2 627 ? 193.810 180.952 220.189 1.00 233.95 ? 645  VAL C CG1 1 
ATOM   10561 C CG2 . VAL B 2 627 ? 192.377 179.071 219.512 1.00 233.95 ? 645  VAL C CG2 1 
ATOM   10562 N N   . CYS B 2 628 ? 193.514 176.412 220.548 1.00 158.05 ? 646  CYS C N   1 
ATOM   10563 C CA  . CYS B 2 628 ? 192.924 175.127 220.921 1.00 158.05 ? 646  CYS C CA  1 
ATOM   10564 C C   . CYS B 2 628 ? 193.821 174.172 221.675 1.00 158.05 ? 646  CYS C C   1 
ATOM   10565 O O   . CYS B 2 628 ? 193.314 173.188 222.213 1.00 158.05 ? 646  CYS C O   1 
ATOM   10566 C CB  . CYS B 2 628 ? 192.358 174.309 219.746 1.00 210.52 ? 646  CYS C CB  1 
ATOM   10567 S SG  . CYS B 2 628 ? 190.903 174.944 218.950 1.00 210.52 ? 646  CYS C SG  1 
ATOM   10568 N N   . TYR B 2 629 ? 195.141 174.333 221.640 1.00 163.16 ? 647  TYR C N   1 
ATOM   10569 C CA  . TYR B 2 629 ? 195.949 173.434 222.431 1.00 163.16 ? 647  TYR C CA  1 
ATOM   10570 C C   . TYR B 2 629 ? 196.366 174.159 223.690 1.00 163.16 ? 647  TYR C C   1 
ATOM   10571 O O   . TYR B 2 629 ? 196.294 173.628 224.798 1.00 163.16 ? 647  TYR C O   1 
ATOM   10572 C CB  . TYR B 2 629 ? 197.266 173.012 221.771 1.00 226.12 ? 647  TYR C CB  1 
ATOM   10573 C CG  . TYR B 2 629 ? 197.866 171.916 222.594 1.00 226.12 ? 647  TYR C CG  1 
ATOM   10574 C CD1 . TYR B 2 629 ? 198.570 172.157 223.779 1.00 226.12 ? 647  TYR C CD1 1 
ATOM   10575 C CD2 . TYR B 2 629 ? 197.608 170.646 222.215 1.00 226.12 ? 647  TYR C CD2 1 
ATOM   10576 C CE1 . TYR B 2 629 ? 198.963 171.102 224.535 1.00 226.12 ? 647  TYR C CE1 1 
ATOM   10577 C CE2 . TYR B 2 629 ? 198.039 169.610 222.967 1.00 226.12 ? 647  TYR C CE2 1 
ATOM   10578 C CZ  . TYR B 2 629 ? 198.694 169.847 224.121 1.00 226.12 ? 647  TYR C CZ  1 
ATOM   10579 O OH  . TYR B 2 629 ? 199.122 168.807 224.843 1.00 226.12 ? 647  TYR C OH  1 
ATOM   10580 N N   . SER B 2 630 ? 196.766 175.398 223.496 1.00 162.98 ? 648  SER C N   1 
ATOM   10581 C CA  . SER B 2 630 ? 197.412 176.194 224.519 1.00 162.98 ? 648  SER C CA  1 
ATOM   10582 C C   . SER B 2 630 ? 196.657 176.442 225.795 1.00 162.98 ? 648  SER C C   1 
ATOM   10583 O O   . SER B 2 630 ? 197.275 176.544 226.852 1.00 162.98 ? 648  SER C O   1 
ATOM   10584 C CB  . SER B 2 630 ? 197.649 177.518 223.947 1.00 218.47 ? 648  SER C CB  1 
ATOM   10585 O OG  . SER B 2 630 ? 196.410 178.118 223.765 1.00 218.47 ? 648  SER C OG  1 
ATOM   10586 N N   . ALA B 2 631 ? 195.334 176.426 225.788 1.00 161.40 ? 649  ALA C N   1 
ATOM   10587 C CA  . ALA B 2 631 ? 194.664 176.625 227.080 1.00 161.40 ? 649  ALA C CA  1 
ATOM   10588 C C   . ALA B 2 631 ? 195.005 175.491 228.065 1.00 161.40 ? 649  ALA C C   1 
ATOM   10589 O O   . ALA B 2 631 ? 194.875 175.650 229.288 1.00 161.40 ? 649  ALA C O   1 
ATOM   10590 C CB  . ALA B 2 631 ? 193.185 176.707 226.922 1.00 218.04 ? 649  ALA C CB  1 
ATOM   10591 N N   . LEU B 2 632 ? 195.451 174.343 227.541 1.00 159.62 ? 650  LEU C N   1 
ATOM   10592 C CA  . LEU B 2 632 ? 195.812 173.201 228.359 1.00 159.62 ? 650  LEU C CA  1 
ATOM   10593 C C   . LEU B 2 632 ? 197.007 173.516 229.211 1.00 159.62 ? 650  LEU C C   1 
ATOM   10594 O O   . LEU B 2 632 ? 197.248 172.859 230.220 1.00 159.62 ? 650  LEU C O   1 
ATOM   10595 C CB  . LEU B 2 632 ? 196.140 171.975 227.492 1.00 226.88 ? 650  LEU C CB  1 
ATOM   10596 C CG  . LEU B 2 632 ? 194.957 171.299 226.755 1.00 226.88 ? 650  LEU C CG  1 
ATOM   10597 C CD1 . LEU B 2 632 ? 195.486 170.308 225.729 1.00 226.88 ? 650  LEU C CD1 1 
ATOM   10598 C CD2 . LEU B 2 632 ? 194.095 170.531 227.781 1.00 226.88 ? 650  LEU C CD2 1 
ATOM   10599 N N   . LEU B 2 633 ? 197.799 174.487 228.803 1.00 164.89 ? 651  LEU C N   1 
ATOM   10600 C CA  . LEU B 2 633 ? 198.999 174.846 229.518 1.00 164.89 ? 651  LEU C CA  1 
ATOM   10601 C C   . LEU B 2 633 ? 198.689 175.202 230.959 1.00 164.89 ? 651  LEU C C   1 
ATOM   10602 O O   . LEU B 2 633 ? 199.337 174.689 231.871 1.00 164.89 ? 651  LEU C O   1 
ATOM   10603 C CB  . LEU B 2 633 ? 199.648 176.038 228.809 1.00 242.19 ? 651  LEU C CB  1 
ATOM   10604 C CG  . LEU B 2 633 ? 201.040 176.551 229.301 1.00 242.19 ? 651  LEU C CG  1 
ATOM   10605 C CD1 . LEU B 2 633 ? 201.752 177.184 228.105 1.00 242.19 ? 651  LEU C CD1 1 
ATOM   10606 C CD2 . LEU B 2 633 ? 200.890 177.625 230.418 1.00 242.19 ? 651  LEU C CD2 1 
ATOM   10607 N N   . THR B 2 634 ? 197.684 176.060 231.187 1.00 158.88 ? 652  THR C N   1 
ATOM   10608 C CA  . THR B 2 634 ? 197.428 176.465 232.557 1.00 158.88 ? 652  THR C CA  1 
ATOM   10609 C C   . THR B 2 634 ? 196.493 175.523 233.241 1.00 158.88 ? 652  THR C C   1 
ATOM   10610 O O   . THR B 2 634 ? 196.484 175.434 234.472 1.00 158.88 ? 652  THR C O   1 
ATOM   10611 C CB  . THR B 2 634 ? 196.814 177.856 232.651 1.00 222.16 ? 652  THR C CB  1 
ATOM   10612 O OG1 . THR B 2 634 ? 195.544 177.844 232.010 1.00 222.16 ? 652  THR C OG1 1 
ATOM   10613 C CG2 . THR B 2 634 ? 197.712 178.849 231.987 1.00 222.16 ? 652  THR C CG2 1 
ATOM   10614 N N   . LYS B 2 635 ? 195.706 174.780 232.470 1.00 161.96 ? 653  LYS C N   1 
ATOM   10615 C CA  . LYS B 2 635 ? 194.846 173.842 233.154 1.00 161.96 ? 653  LYS C CA  1 
ATOM   10616 C C   . LYS B 2 635 ? 195.761 172.811 233.769 1.00 161.96 ? 653  LYS C C   1 
ATOM   10617 O O   . LYS B 2 635 ? 195.627 172.448 234.942 1.00 161.96 ? 653  LYS C O   1 
ATOM   10618 C CB  . LYS B 2 635 ? 193.891 173.172 232.183 1.00 240.83 ? 653  LYS C CB  1 
ATOM   10619 C CG  . LYS B 2 635 ? 192.851 174.087 231.610 1.00 240.83 ? 653  LYS C CG  1 
ATOM   10620 C CD  . LYS B 2 635 ? 191.957 173.340 230.668 1.00 240.83 ? 653  LYS C CD  1 
ATOM   10621 C CE  . LYS B 2 635 ? 191.023 174.265 229.960 1.00 240.83 ? 653  LYS C CE  1 
ATOM   10622 N NZ  . LYS B 2 635 ? 190.041 173.530 229.100 1.00 240.83 ? 653  LYS C NZ  1 
ATOM   10623 N N   . THR B 2 636 ? 196.753 172.404 232.981 1.00 164.42 ? 654  THR C N   1 
ATOM   10624 C CA  . THR B 2 636 ? 197.704 171.423 233.392 1.00 164.42 ? 654  THR C CA  1 
ATOM   10625 C C   . THR B 2 636 ? 198.554 171.965 234.487 1.00 164.42 ? 654  THR C C   1 
ATOM   10626 O O   . THR B 2 636 ? 198.805 171.273 235.465 1.00 164.42 ? 654  THR C O   1 
ATOM   10627 C CB  . THR B 2 636 ? 198.631 171.029 232.245 1.00 229.90 ? 654  THR C CB  1 
ATOM   10628 O OG1 . THR B 2 636 ? 197.875 170.519 231.171 1.00 229.90 ? 654  THR C OG1 1 
ATOM   10629 C CG2 . THR B 2 636 ? 199.548 169.958 232.722 1.00 229.90 ? 654  THR C CG2 1 
ATOM   10630 N N   . ASN B 2 637 ? 199.029 173.197 234.344 1.00 165.01 ? 655  ASN C N   1 
ATOM   10631 C CA  . ASN B 2 637 ? 199.894 173.776 235.337 1.00 165.01 ? 655  ASN C CA  1 
ATOM   10632 C C   . ASN B 2 637 ? 199.249 173.822 236.710 1.00 165.01 ? 655  ASN C C   1 
ATOM   10633 O O   . ASN B 2 637 ? 199.880 173.446 237.692 1.00 165.01 ? 655  ASN C O   1 
ATOM   10634 C CB  . ASN B 2 637 ? 200.328 175.180 234.913 1.00 30.00  ? 655  ASN C CB  1 
ATOM   10635 C CG  . ASN B 2 637 ? 201.300 175.164 233.749 1.00 30.00  ? 655  ASN C CG  1 
ATOM   10636 O OD1 . ASN B 2 637 ? 201.982 174.168 233.509 1.00 30.00  ? 655  ASN C OD1 1 
ATOM   10637 N ND2 . ASN B 2 637 ? 201.368 176.271 233.019 1.00 30.00  ? 655  ASN C ND2 1 
ATOM   10638 N N   . ARG B 2 638 ? 197.998 174.322 236.804 1.00 163.33 ? 656  ARG C N   1 
ATOM   10639 C CA  . ARG B 2 638 ? 197.437 174.427 238.142 1.00 163.33 ? 656  ARG C CA  1 
ATOM   10640 C C   . ARG B 2 638 ? 197.173 173.063 238.777 1.00 163.33 ? 656  ARG C C   1 
ATOM   10641 O O   . ARG B 2 638 ? 197.289 172.924 239.997 1.00 163.33 ? 656  ARG C O   1 
ATOM   10642 C CB  . ARG B 2 638 ? 196.155 175.264 238.182 1.00 238.79 ? 656  ARG C CB  1 
ATOM   10643 C CG  . ARG B 2 638 ? 194.886 174.677 237.542 1.00 238.79 ? 656  ARG C CG  1 
ATOM   10644 C CD  . ARG B 2 638 ? 193.691 175.582 237.751 1.00 238.79 ? 656  ARG C CD  1 
ATOM   10645 N NE  . ARG B 2 638 ? 193.393 175.721 239.184 1.00 238.79 ? 656  ARG C NE  1 
ATOM   10646 C CZ  . ARG B 2 638 ? 192.697 174.824 239.929 1.00 238.79 ? 656  ARG C CZ  1 
ATOM   10647 N NH1 . ARG B 2 638 ? 192.529 174.994 241.220 1.00 238.79 ? 656  ARG C NH1 1 
ATOM   10648 N NH2 . ARG B 2 638 ? 192.185 173.756 239.406 1.00 238.79 ? 656  ARG C NH2 1 
ATOM   10649 N N   . ILE B 2 639 ? 196.879 172.042 237.969 1.00 163.05 ? 657  ILE C N   1 
ATOM   10650 C CA  . ILE B 2 639 ? 196.652 170.699 238.509 1.00 163.05 ? 657  ILE C CA  1 
ATOM   10651 C C   . ILE B 2 639 ? 197.984 169.942 238.823 1.00 163.05 ? 657  ILE C C   1 
ATOM   10652 O O   . ILE B 2 639 ? 198.100 169.336 239.888 1.00 163.05 ? 657  ILE C O   1 
ATOM   10653 C CB  . ILE B 2 639 ? 195.727 169.883 237.554 1.00 240.30 ? 657  ILE C CB  1 
ATOM   10654 C CG1 . ILE B 2 639 ? 194.312 170.574 237.387 1.00 240.30 ? 657  ILE C CG1 1 
ATOM   10655 C CG2 . ILE B 2 639 ? 195.541 168.444 238.054 1.00 240.30 ? 657  ILE C CG2 1 
ATOM   10656 C CD1 . ILE B 2 639 ? 193.478 170.756 238.661 1.00 240.30 ? 657  ILE C CD1 1 
ATOM   10657 N N   . ALA B 2 640 ? 198.982 169.984 237.900 1.00 160.60 ? 658  ALA C N   1 
ATOM   10658 C CA  . ALA B 2 640 ? 200.291 169.323 237.964 1.00 160.60 ? 658  ALA C CA  1 
ATOM   10659 C C   . ALA B 2 640 ? 201.126 169.890 239.115 1.00 160.60 ? 658  ALA C C   1 
ATOM   10660 O O   . ALA B 2 640 ? 202.179 169.341 239.470 1.00 160.60 ? 658  ALA C O   1 
ATOM   10661 C CB  . ALA B 2 640 ? 201.051 169.500 236.620 1.00 216.96 ? 658  ALA C CB  1 
ATOM   10662 N N   . ILE B 2 656 ? 201.318 186.347 240.392 1.00 172.42 ? 674  ILE C N   1 
ATOM   10663 C CA  . ILE B 2 656 ? 201.464 185.055 239.702 1.00 172.42 ? 674  ILE C CA  1 
ATOM   10664 C C   . ILE B 2 656 ? 200.438 183.967 240.168 1.00 172.42 ? 674  ILE C C   1 
ATOM   10665 O O   . ILE B 2 656 ? 200.703 182.761 240.047 1.00 172.42 ? 674  ILE C O   1 
ATOM   10666 C CB  . ILE B 2 656 ? 202.972 184.533 239.772 1.00 254.11 ? 674  ILE C CB  1 
ATOM   10667 C CG1 . ILE B 2 656 ? 203.468 184.277 241.336 1.00 254.11 ? 674  ILE C CG1 1 
ATOM   10668 C CG2 . ILE B 2 656 ? 203.967 185.523 238.964 1.00 254.11 ? 674  ILE C CG2 1 
ATOM   10669 C CD1 . ILE B 2 656 ? 204.830 183.527 241.493 1.00 254.11 ? 674  ILE C CD1 1 
ATOM   10670 N N   . SER B 2 657 ? 199.251 184.412 240.658 1.00 176.99 ? 675  SER C N   1 
ATOM   10671 C CA  . SER B 2 657 ? 198.091 183.620 241.097 1.00 176.99 ? 675  SER C CA  1 
ATOM   10672 C C   . SER B 2 657 ? 197.415 183.100 239.828 1.00 176.99 ? 675  SER C C   1 
ATOM   10673 O O   . SER B 2 657 ? 197.717 183.628 238.758 1.00 176.99 ? 675  SER C O   1 
ATOM   10674 C CB  . SER B 2 657 ? 197.154 184.520 241.889 1.00 237.25 ? 675  SER C CB  1 
ATOM   10675 O OG  . SER B 2 657 ? 196.502 185.437 241.046 1.00 237.25 ? 675  SER C OG  1 
ATOM   10676 N N   . PRO B 2 658 ? 196.468 182.148 239.870 1.00 176.18 ? 676  PRO C N   1 
ATOM   10677 C CA  . PRO B 2 658 ? 195.794 181.629 238.693 1.00 176.18 ? 676  PRO C CA  1 
ATOM   10678 C C   . PRO B 2 658 ? 195.297 182.722 237.754 1.00 176.18 ? 676  PRO C C   1 
ATOM   10679 O O   . PRO B 2 658 ? 195.365 182.556 236.543 1.00 176.18 ? 676  PRO C O   1 
ATOM   10680 C CB  . PRO B 2 658 ? 194.643 180.838 239.309 1.00 359.58 ? 676  PRO C CB  1 
ATOM   10681 C CG  . PRO B 2 658 ? 195.205 180.356 240.630 1.00 359.58 ? 676  PRO C CG  1 
ATOM   10682 C CD  . PRO B 2 658 ? 196.042 181.513 241.135 1.00 359.58 ? 676  PRO C CD  1 
ATOM   10683 N N   . ALA B 2 659 ? 194.834 183.860 238.270 1.00 170.60 ? 677  ALA C N   1 
ATOM   10684 C CA  . ALA B 2 659 ? 194.389 184.907 237.361 1.00 170.60 ? 677  ALA C CA  1 
ATOM   10685 C C   . ALA B 2 659 ? 195.554 185.434 236.508 1.00 170.60 ? 677  ALA C C   1 
ATOM   10686 O O   . ALA B 2 659 ? 195.362 185.821 235.345 1.00 170.60 ? 677  ALA C O   1 
ATOM   10687 C CB  . ALA B 2 659 ? 193.759 186.036 238.144 1.00 230.47 ? 677  ALA C CB  1 
ATOM   10688 N N   . SER B 2 660 ? 196.759 185.491 237.094 1.00 179.63 ? 678  SER C N   1 
ATOM   10689 C CA  . SER B 2 660 ? 197.912 186.012 236.390 1.00 179.63 ? 678  SER C CA  1 
ATOM   10690 C C   . SER B 2 660 ? 198.488 184.929 235.529 1.00 179.63 ? 678  SER C C   1 
ATOM   10691 O O   . SER B 2 660 ? 198.994 185.198 234.448 1.00 179.63 ? 678  SER C O   1 
ATOM   10692 C CB  . SER B 2 660 ? 198.972 186.498 237.353 1.00 239.26 ? 678  SER C CB  1 
ATOM   10693 O OG  . SER B 2 660 ? 198.557 187.616 238.086 1.00 239.26 ? 678  SER C OG  1 
ATOM   10694 N N   . GLN B 2 661 ? 198.341 183.685 235.966 1.00 179.60 ? 679  GLN C N   1 
ATOM   10695 C CA  . GLN B 2 661 ? 198.874 182.553 235.228 1.00 179.60 ? 679  GLN C CA  1 
ATOM   10696 C C   . GLN B 2 661 ? 198.151 182.492 233.889 1.00 179.60 ? 679  GLN C C   1 
ATOM   10697 O O   . GLN B 2 661 ? 198.758 182.233 232.840 1.00 179.60 ? 679  GLN C O   1 
ATOM   10698 C CB  . GLN B 2 661 ? 198.660 181.281 236.043 1.00 250.32 ? 679  GLN C CB  1 
ATOM   10699 C CG  . GLN B 2 661 ? 199.509 181.231 237.319 1.00 250.32 ? 679  GLN C CG  1 
ATOM   10700 C CD  . GLN B 2 661 ? 199.109 180.118 238.281 1.00 250.32 ? 679  GLN C CD  1 
ATOM   10701 O OE1 . GLN B 2 661 ? 198.511 179.106 237.890 1.00 250.32 ? 679  GLN C OE1 1 
ATOM   10702 N NE2 . GLN B 2 661 ? 199.420 180.318 239.557 1.00 250.32 ? 679  GLN C NE2 1 
ATOM   10703 N N   . VAL B 2 662 ? 196.858 182.803 233.930 1.00 175.68 ? 680  VAL C N   1 
ATOM   10704 C CA  . VAL B 2 662 ? 196.045 182.861 232.743 1.00 175.68 ? 680  VAL C CA  1 
ATOM   10705 C C   . VAL B 2 662 ? 196.489 183.994 231.845 1.00 175.68 ? 680  VAL C C   1 
ATOM   10706 O O   . VAL B 2 662 ? 196.672 183.786 230.647 1.00 175.68 ? 680  VAL C O   1 
ATOM   10707 C CB  . VAL B 2 662 ? 194.570 183.037 233.130 1.00 254.62 ? 680  VAL C CB  1 
ATOM   10708 C CG1 . VAL B 2 662 ? 193.749 183.339 231.948 1.00 254.62 ? 680  VAL C CG1 1 
ATOM   10709 C CG2 . VAL B 2 662 ? 194.044 181.734 233.729 1.00 254.62 ? 680  VAL C CG2 1 
ATOM   10710 N N   . ALA B 2 663 ? 196.691 185.185 232.413 1.00 177.01 ? 681  ALA C N   1 
ATOM   10711 C CA  . ALA B 2 663 ? 197.126 186.312 231.613 1.00 177.01 ? 681  ALA C CA  1 
ATOM   10712 C C   . ALA B 2 663 ? 198.469 186.041 230.952 1.00 177.01 ? 681  ALA C C   1 
ATOM   10713 O O   . ALA B 2 663 ? 198.688 186.417 229.794 1.00 177.01 ? 681  ALA C O   1 
ATOM   10714 C CB  . ALA B 2 663 ? 197.215 187.544 232.481 1.00 239.13 ? 681  ALA C CB  1 
ATOM   10715 N N   . ILE B 2 664 ? 199.348 185.345 231.666 1.00 179.33 ? 682  ILE C N   1 
ATOM   10716 C CA  . ILE B 2 664 ? 200.652 185.017 231.149 1.00 179.33 ? 682  ILE C CA  1 
ATOM   10717 C C   . ILE B 2 664 ? 200.500 184.090 229.978 1.00 179.33 ? 682  ILE C C   1 
ATOM   10718 O O   . ILE B 2 664 ? 201.126 184.302 228.939 1.00 179.33 ? 682  ILE C O   1 
ATOM   10719 C CB  . ILE B 2 664 ? 201.531 184.403 232.246 1.00 254.89 ? 682  ILE C CB  1 
ATOM   10720 C CG1 . ILE B 2 664 ? 201.845 185.518 233.301 1.00 254.89 ? 682  ILE C CG1 1 
ATOM   10721 C CG2 . ILE B 2 664 ? 202.821 183.820 231.611 1.00 254.89 ? 682  ILE C CG2 1 
ATOM   10722 C CD1 . ILE B 2 664 ? 202.389 185.023 234.645 1.00 254.89 ? 682  ILE C CD1 1 
ATOM   10723 N N   . CYS B 2 665 ? 199.665 183.071 230.116 1.00 182.77 ? 683  CYS C N   1 
ATOM   10724 C CA  . CYS B 2 665 ? 199.464 182.168 229.015 1.00 182.77 ? 683  CYS C CA  1 
ATOM   10725 C C   . CYS B 2 665 ? 198.918 182.900 227.812 1.00 182.77 ? 683  CYS C C   1 
ATOM   10726 O O   . CYS B 2 665 ? 199.346 182.627 226.690 1.00 182.77 ? 683  CYS C O   1 
ATOM   10727 C CB  . CYS B 2 665 ? 198.520 181.076 229.362 1.00 244.99 ? 683  CYS C CB  1 
ATOM   10728 S SG  . CYS B 2 665 ? 198.334 179.849 228.050 1.00 244.99 ? 683  CYS C SG  1 
ATOM   10729 N N   . LEU B 2 666 ? 197.956 183.789 228.017 1.00 185.49 ? 684  LEU C N   1 
ATOM   10730 C CA  . LEU B 2 666 ? 197.371 184.488 226.891 1.00 185.49 ? 684  LEU C CA  1 
ATOM   10731 C C   . LEU B 2 666 ? 198.434 185.294 226.177 1.00 185.49 ? 684  LEU C C   1 
ATOM   10732 O O   . LEU B 2 666 ? 198.487 185.317 224.940 1.00 185.49 ? 684  LEU C O   1 
ATOM   10733 C CB  . LEU B 2 666 ? 196.261 185.408 227.409 1.00 263.65 ? 684  LEU C CB  1 
ATOM   10734 C CG  . LEU B 2 666 ? 194.996 184.697 227.960 1.00 263.65 ? 684  LEU C CG  1 
ATOM   10735 C CD1 . LEU B 2 666 ? 194.123 185.687 228.706 1.00 263.65 ? 684  LEU C CD1 1 
ATOM   10736 C CD2 . LEU B 2 666 ? 194.192 184.108 226.818 1.00 263.65 ? 684  LEU C CD2 1 
ATOM   10737 N N   . ALA B 2 667 ? 199.314 185.923 226.944 1.00 193.88 ? 685  ALA C N   1 
ATOM   10738 C CA  . ALA B 2 667 ? 200.387 186.683 226.350 1.00 193.88 ? 685  ALA C CA  1 
ATOM   10739 C C   . ALA B 2 667 ? 201.327 185.794 225.547 1.00 193.88 ? 685  ALA C C   1 
ATOM   10740 O O   . ALA B 2 667 ? 201.780 186.191 224.470 1.00 193.88 ? 685  ALA C O   1 
ATOM   10741 C CB  . ALA B 2 667 ? 201.158 187.396 227.435 1.00 261.92 ? 685  ALA C CB  1 
ATOM   10742 N N   . LEU B 2 668 ? 201.604 184.587 226.045 1.00 187.94 ? 686  LEU C N   1 
ATOM   10743 C CA  . LEU B 2 668 ? 202.497 183.677 225.344 1.00 187.94 ? 686  LEU C CA  1 
ATOM   10744 C C   . LEU B 2 668 ? 201.892 183.228 224.034 1.00 187.94 ? 686  LEU C C   1 
ATOM   10745 O O   . LEU B 2 668 ? 202.592 183.135 223.015 1.00 187.94 ? 686  LEU C O   1 
ATOM   10746 C CB  . LEU B 2 668 ? 202.777 182.431 226.192 1.00 267.13 ? 686  LEU C CB  1 
ATOM   10747 C CG  . LEU B 2 668 ? 203.613 182.615 227.479 1.00 267.13 ? 686  LEU C CG  1 
ATOM   10748 C CD1 . LEU B 2 668 ? 203.582 181.305 228.275 1.00 267.13 ? 686  LEU C CD1 1 
ATOM   10749 C CD2 . LEU B 2 668 ? 205.049 182.998 227.133 1.00 267.13 ? 686  LEU C CD2 1 
ATOM   10750 N N   . ILE B 2 669 ? 200.578 183.007 224.036 1.00 194.58 ? 687  ILE C N   1 
ATOM   10751 C CA  . ILE B 2 669 ? 199.904 182.555 222.835 1.00 194.58 ? 687  ILE C CA  1 
ATOM   10752 C C   . ILE B 2 669 ? 200.005 183.597 221.756 1.00 194.58 ? 687  ILE C C   1 
ATOM   10753 O O   . ILE B 2 669 ? 200.403 183.291 220.618 1.00 194.58 ? 687  ILE C O   1 
ATOM   10754 C CB  . ILE B 2 669 ? 198.393 182.319 223.110 1.00 286.77 ? 687  ILE C CB  1 
ATOM   10755 C CG1 . ILE B 2 669 ? 198.206 181.114 224.051 1.00 286.77 ? 687  ILE C CG1 1 
ATOM   10756 C CG2 . ILE B 2 669 ? 197.622 182.112 221.761 1.00 286.77 ? 687  ILE C CG2 1 
ATOM   10757 C CD1 . ILE B 2 669 ? 196.793 180.985 224.663 1.00 286.77 ? 687  ILE C CD1 1 
ATOM   10758 N N   . SER B 2 670 ? 199.683 184.836 222.114 1.00 206.10 ? 688  SER C N   1 
ATOM   10759 C CA  . SER B 2 670 ? 199.721 185.879 221.127 1.00 206.10 ? 688  SER C CA  1 
ATOM   10760 C C   . SER B 2 670 ? 201.139 186.159 220.708 1.00 206.10 ? 688  SER C C   1 
ATOM   10761 O O   . SER B 2 670 ? 201.409 186.295 219.517 1.00 206.10 ? 688  SER C O   1 
ATOM   10762 C CB  . SER B 2 670 ? 199.081 187.144 221.663 1.00 276.27 ? 688  SER C CB  1 
ATOM   10763 O OG  . SER B 2 670 ? 197.699 186.979 221.868 1.00 276.27 ? 688  SER C OG  1 
ATOM   10764 N N   . GLY B 2 671 ? 202.067 186.156 221.657 1.00 204.56 ? 689  GLY C N   1 
ATOM   10765 C CA  . GLY B 2 671 ? 203.440 186.466 221.362 1.00 204.56 ? 689  GLY C CA  1 
ATOM   10766 C C   . GLY B 2 671 ? 204.020 185.550 220.309 1.00 204.56 ? 689  GLY C C   1 
ATOM   10767 O O   . GLY B 2 671 ? 204.542 186.020 219.292 1.00 204.56 ? 689  GLY C O   1 
ATOM   10768 N N   . GLN B 2 672 ? 203.946 184.246 220.526 1.00 195.52 ? 690  GLN C N   1 
ATOM   10769 C CA  . GLN B 2 672 ? 204.583 183.389 219.554 1.00 195.52 ? 690  GLN C CA  1 
ATOM   10770 C C   . GLN B 2 672 ? 203.931 183.441 218.181 1.00 195.52 ? 690  GLN C C   1 
ATOM   10771 O O   . GLN B 2 672 ? 204.628 183.380 217.154 1.00 195.52 ? 690  GLN C O   1 
ATOM   10772 C CB  . GLN B 2 672 ? 204.633 181.958 220.052 1.00 272.51 ? 690  GLN C CB  1 
ATOM   10773 C CG  . GLN B 2 672 ? 205.408 181.065 219.139 1.00 272.51 ? 690  GLN C CG  1 
ATOM   10774 C CD  . GLN B 2 672 ? 206.875 181.435 219.022 1.00 272.51 ? 690  GLN C CD  1 
ATOM   10775 O OE1 . GLN B 2 672 ? 207.596 181.482 220.024 1.00 272.51 ? 690  GLN C OE1 1 
ATOM   10776 N NE2 . GLN B 2 672 ? 207.327 181.712 217.798 1.00 272.51 ? 690  GLN C NE2 1 
ATOM   10777 N N   . LEU B 2 673 ? 202.608 183.550 218.115 1.00 200.42 ? 691  LEU C N   1 
ATOM   10778 C CA  . LEU B 2 673 ? 202.035 183.573 216.789 1.00 200.42 ? 691  LEU C CA  1 
ATOM   10779 C C   . LEU B 2 673 ? 202.382 184.879 216.102 1.00 200.42 ? 691  LEU C C   1 
ATOM   10780 O O   . LEU B 2 673 ? 202.660 184.873 214.908 1.00 200.42 ? 691  LEU C O   1 
ATOM   10781 C CB  . LEU B 2 673 ? 200.529 183.303 216.784 1.00 284.87 ? 691  LEU C CB  1 
ATOM   10782 C CG  . LEU B 2 673 ? 199.835 183.170 215.333 1.00 284.87 ? 691  LEU C CG  1 
ATOM   10783 C CD1 . LEU B 2 673 ? 200.488 182.035 214.476 1.00 284.87 ? 691  LEU C CD1 1 
ATOM   10784 C CD2 . LEU B 2 673 ? 198.378 182.835 215.516 1.00 284.87 ? 691  LEU C CD2 1 
ATOM   10785 N N   . LEU B 2 674 ? 202.426 185.987 216.847 1.00 206.42 ? 692  LEU C N   1 
ATOM   10786 C CA  . LEU B 2 674 ? 202.766 187.281 216.282 1.00 206.42 ? 692  LEU C CA  1 
ATOM   10787 C C   . LEU B 2 674 ? 204.173 187.287 215.714 1.00 206.42 ? 692  LEU C C   1 
ATOM   10788 O O   . LEU B 2 674 ? 204.438 188.002 214.743 1.00 206.42 ? 692  LEU C O   1 
ATOM   10789 C CB  . LEU B 2 674 ? 202.590 188.381 217.318 1.00 293.39 ? 692  LEU C CB  1 
ATOM   10790 C CG  . LEU B 2 674 ? 201.125 188.728 217.699 1.00 293.39 ? 692  LEU C CG  1 
ATOM   10791 C CD1 . LEU B 2 674 ? 201.146 189.628 218.918 1.00 293.39 ? 692  LEU C CD1 1 
ATOM   10792 C CD2 . LEU B 2 674 ? 200.433 189.446 216.532 1.00 293.39 ? 692  LEU C CD2 1 
ATOM   10793 N N   . ILE B 2 675 ? 205.086 186.503 216.292 1.00 207.83 ? 693  ILE C N   1 
ATOM   10794 C CA  . ILE B 2 675 ? 206.414 186.428 215.710 1.00 207.83 ? 693  ILE C CA  1 
ATOM   10795 C C   . ILE B 2 675 ? 206.257 185.873 214.313 1.00 207.83 ? 693  ILE C C   1 
ATOM   10796 O O   . ILE B 2 675 ? 206.807 186.410 213.348 1.00 207.83 ? 693  ILE C O   1 
ATOM   10797 C CB  . ILE B 2 675 ? 207.356 185.523 216.527 1.00 306.29 ? 693  ILE C CB  1 
ATOM   10798 C CG1 . ILE B 2 675 ? 207.664 186.193 217.879 1.00 306.29 ? 693  ILE C CG1 1 
ATOM   10799 C CG2 . ILE B 2 675 ? 208.614 185.202 215.714 1.00 306.29 ? 693  ILE C CG2 1 
ATOM   10800 C CD1 . ILE B 2 675 ? 208.338 185.287 218.905 1.00 306.29 ? 693  ILE C CD1 1 
ATOM   10801 N N   . VAL B 2 676 ? 205.463 184.824 214.198 1.00 205.77 ? 694  VAL C N   1 
ATOM   10802 C CA  . VAL B 2 676 ? 205.234 184.251 212.893 1.00 205.77 ? 694  VAL C CA  1 
ATOM   10803 C C   . VAL B 2 676 ? 204.496 185.247 211.998 1.00 205.77 ? 694  VAL C C   1 
ATOM   10804 O O   . VAL B 2 676 ? 204.833 185.378 210.822 1.00 205.77 ? 694  VAL C O   1 
ATOM   10805 C CB  . VAL B 2 676 ? 204.490 182.920 212.974 1.00 289.77 ? 694  VAL C CB  1 
ATOM   10806 C CG1 . VAL B 2 676 ? 204.147 182.441 211.563 1.00 289.77 ? 694  VAL C CG1 1 
ATOM   10807 C CG2 . VAL B 2 676 ? 205.368 181.914 213.702 1.00 289.77 ? 694  VAL C CG2 1 
ATOM   10808 N N   . VAL B 2 677 ? 203.533 185.984 212.541 1.00 201.24 ? 695  VAL C N   1 
ATOM   10809 C CA  . VAL B 2 677 ? 202.807 186.930 211.718 1.00 201.24 ? 695  VAL C CA  1 
ATOM   10810 C C   . VAL B 2 677 ? 203.786 187.858 211.073 1.00 201.24 ? 695  VAL C C   1 
ATOM   10811 O O   . VAL B 2 677 ? 203.803 187.964 209.849 1.00 201.24 ? 695  VAL C O   1 
ATOM   10812 C CB  . VAL B 2 677 ? 201.836 187.788 212.559 1.00 283.39 ? 695  VAL C CB  1 
ATOM   10813 C CG1 . VAL B 2 677 ? 201.252 188.897 211.731 1.00 283.39 ? 695  VAL C CG1 1 
ATOM   10814 C CG2 . VAL B 2 677 ? 200.731 186.936 213.114 1.00 283.39 ? 695  VAL C CG2 1 
ATOM   10815 N N   . ALA B 2 678 ? 204.725 188.384 211.848 1.00 204.61 ? 696  ALA C N   1 
ATOM   10816 C CA  . ALA B 2 678 ? 205.710 189.298 211.306 1.00 204.61 ? 696  ALA C CA  1 
ATOM   10817 C C   . ALA B 2 678 ? 206.482 188.667 210.157 1.00 204.61 ? 696  ALA C C   1 
ATOM   10818 O O   . ALA B 2 678 ? 206.873 189.353 209.215 1.00 204.61 ? 696  ALA C O   1 
ATOM   10819 C CB  . ALA B 2 678 ? 206.677 189.709 212.390 1.00 276.42 ? 696  ALA C CB  1 
ATOM   10820 N N   . TRP B 2 679 ? 206.731 187.362 210.243 1.00 206.78 ? 697  TRP C N   1 
ATOM   10821 C CA  . TRP B 2 679 ? 207.456 186.659 209.210 1.00 206.78 ? 697  TRP C CA  1 
ATOM   10822 C C   . TRP B 2 679 ? 206.650 186.444 207.941 1.00 206.78 ? 697  TRP C C   1 
ATOM   10823 O O   . TRP B 2 679 ? 207.222 186.319 206.862 1.00 206.78 ? 697  TRP C O   1 
ATOM   10824 C CB  . TRP B 2 679 ? 207.855 185.267 209.682 1.00 287.02 ? 697  TRP C CB  1 
ATOM   10825 C CG  . TRP B 2 679 ? 208.800 185.225 210.800 1.00 287.02 ? 697  TRP C CG  1 
ATOM   10826 C CD1 . TRP B 2 679 ? 209.527 186.250 211.308 1.00 287.02 ? 697  TRP C CD1 1 
ATOM   10827 C CD2 . TRP B 2 679 ? 209.154 184.063 211.573 1.00 287.02 ? 697  TRP C CD2 1 
ATOM   10828 N NE1 . TRP B 2 679 ? 210.307 185.805 212.334 1.00 287.02 ? 697  TRP C NE1 1 
ATOM   10829 C CE2 . TRP B 2 679 ? 210.092 184.470 212.507 1.00 287.02 ? 697  TRP C CE2 1 
ATOM   10830 C CE3 . TRP B 2 679 ? 208.760 182.730 211.544 1.00 287.02 ? 697  TRP C CE3 1 
ATOM   10831 C CZ2 . TRP B 2 679 ? 210.649 183.596 213.407 1.00 287.02 ? 697  TRP C CZ2 1 
ATOM   10832 C CZ3 . TRP B 2 679 ? 209.324 181.861 212.448 1.00 287.02 ? 697  TRP C CZ3 1 
ATOM   10833 C CH2 . TRP B 2 679 ? 210.239 182.280 213.353 1.00 287.02 ? 697  TRP C CH2 1 
ATOM   10834 N N   . LEU B 2 680 ? 205.331 186.368 208.048 1.00 200.10 ? 698  LEU C N   1 
ATOM   10835 C CA  . LEU B 2 680 ? 204.552 186.076 206.859 1.00 200.10 ? 698  LEU C CA  1 
ATOM   10836 C C   . LEU B 2 680 ? 203.934 187.291 206.200 1.00 200.10 ? 698  LEU C C   1 
ATOM   10837 O O   . LEU B 2 680 ? 203.757 187.313 204.981 1.00 200.10 ? 698  LEU C O   1 
ATOM   10838 C CB  . LEU B 2 680 ? 203.490 185.047 207.191 1.00 284.41 ? 698  LEU C CB  1 
ATOM   10839 C CG  . LEU B 2 680 ? 204.030 183.694 207.736 1.00 284.41 ? 698  LEU C CG  1 
ATOM   10840 C CD1 . LEU B 2 680 ? 202.850 182.806 208.012 1.00 284.41 ? 698  LEU C CD1 1 
ATOM   10841 C CD2 . LEU B 2 680 ? 205.022 183.021 206.754 1.00 284.41 ? 698  LEU C CD2 1 
ATOM   10842 N N   . VAL B 2 681 ? 203.681 188.339 206.968 1.00 197.61 ? 699  VAL C N   1 
ATOM   10843 C CA  . VAL B 2 681 ? 203.053 189.551 206.434 1.00 197.61 ? 699  VAL C CA  1 
ATOM   10844 C C   . VAL B 2 681 ? 204.019 190.324 205.557 1.00 197.61 ? 699  VAL C C   1 
ATOM   10845 O O   . VAL B 2 681 ? 203.652 191.317 204.935 1.00 197.61 ? 699  VAL C O   1 
ATOM   10846 C CB  . VAL B 2 681 ? 202.499 190.471 207.542 1.00 278.28 ? 699  VAL C CB  1 
ATOM   10847 C CG1 . VAL B 2 681 ? 201.443 189.746 208.342 1.00 278.28 ? 699  VAL C CG1 1 
ATOM   10848 C CG2 . VAL B 2 681 ? 203.624 190.939 208.430 1.00 278.28 ? 699  VAL C CG2 1 
ATOM   10849 N N   . VAL B 2 682 ? 205.262 189.882 205.552 1.00 207.67 ? 700  VAL C N   1 
ATOM   10850 C CA  . VAL B 2 682 ? 206.326 190.480 204.792 1.00 207.67 ? 700  VAL C CA  1 
ATOM   10851 C C   . VAL B 2 682 ? 206.684 189.662 203.560 1.00 207.67 ? 700  VAL C C   1 
ATOM   10852 O O   . VAL B 2 682 ? 207.654 189.982 202.871 1.00 207.67 ? 700  VAL C O   1 
ATOM   10853 C CB  . VAL B 2 682 ? 207.576 190.618 205.670 1.00 292.45 ? 700  VAL C CB  1 
ATOM   10854 C CG1 . VAL B 2 682 ? 207.278 191.493 206.854 1.00 292.45 ? 700  VAL C CG1 1 
ATOM   10855 C CG2 . VAL B 2 682 ? 208.014 189.255 206.147 1.00 292.45 ? 700  VAL C CG2 1 
ATOM   10856 N N   . GLU B 2 683 ? 205.932 188.602 203.278 1.00 213.43 ? 701  GLU C N   1 
ATOM   10857 C CA  . GLU B 2 683 ? 206.225 187.797 202.103 1.00 213.43 ? 701  GLU C CA  1 
ATOM   10858 C C   . GLU B 2 683 ? 205.623 188.445 200.861 1.00 213.43 ? 701  GLU C C   1 
ATOM   10859 O O   . GLU B 2 683 ? 204.423 188.706 200.804 1.00 213.43 ? 701  GLU C O   1 
ATOM   10860 C CB  . GLU B 2 683 ? 205.671 186.388 202.278 1.00 286.43 ? 701  GLU C CB  1 
ATOM   10861 C CG  . GLU B 2 683 ? 206.380 185.524 203.318 1.00 286.43 ? 701  GLU C CG  1 
ATOM   10862 C CD  . GLU B 2 683 ? 207.729 185.050 202.874 1.00 286.43 ? 701  GLU C CD  1 
ATOM   10863 O OE1 . GLU B 2 683 ? 208.039 185.229 201.719 1.00 286.43 ? 701  GLU C OE1 1 
ATOM   10864 O OE2 . GLU B 2 683 ? 208.448 184.499 203.671 1.00 286.43 ? 701  GLU C OE2 1 
ATOM   10865 N N   . ALA B 2 684 ? 206.473 188.743 199.882 1.00 221.28 ? 702  ALA C N   1 
ATOM   10866 C CA  . ALA B 2 684 ? 206.034 189.409 198.660 1.00 221.28 ? 702  ALA C CA  1 
ATOM   10867 C C   . ALA B 2 684 ? 205.169 188.561 197.703 1.00 221.28 ? 702  ALA C C   1 
ATOM   10868 O O   . ALA B 2 684 ? 204.226 189.107 197.136 1.00 221.28 ? 702  ALA C O   1 
ATOM   10869 C CB  . ALA B 2 684 ? 207.233 189.965 197.896 1.00 298.94 ? 702  ALA C CB  1 
ATOM   10870 N N   . PRO B 2 685 ? 205.467 187.267 197.414 1.00 211.58 ? 703  PRO C N   1 
ATOM   10871 C CA  . PRO B 2 685 ? 204.709 186.483 196.448 1.00 211.58 ? 703  PRO C CA  1 
ATOM   10872 C C   . PRO B 2 685 ? 203.243 186.400 196.847 1.00 211.58 ? 703  PRO C C   1 
ATOM   10873 O O   . PRO B 2 685 ? 202.931 186.104 198.008 1.00 211.58 ? 703  PRO C O   1 
ATOM   10874 C CB  . PRO B 2 685 ? 205.390 185.112 196.507 1.00 361.54 ? 703  PRO C CB  1 
ATOM   10875 C CG  . PRO B 2 685 ? 206.785 185.402 197.022 1.00 361.54 ? 703  PRO C CG  1 
ATOM   10876 C CD  . PRO B 2 685 ? 206.595 186.538 198.019 1.00 361.54 ? 703  PRO C CD  1 
ATOM   10877 N N   . GLY B 2 686 ? 202.356 186.597 195.863 1.00 218.29 ? 704  GLY C N   1 
ATOM   10878 C CA  . GLY B 2 686 ? 200.917 186.562 196.088 1.00 218.29 ? 704  GLY C CA  1 
ATOM   10879 C C   . GLY B 2 686 ? 200.193 185.500 195.276 1.00 218.29 ? 704  GLY C C   1 
ATOM   10880 O O   . GLY B 2 686 ? 200.749 184.427 194.998 1.00 218.29 ? 704  GLY C O   1 
ATOM   10881 N N   . THR B 2 687 ? 198.934 185.804 194.930 1.00 223.20 ? 705  THR C N   1 
ATOM   10882 C CA  . THR B 2 687 ? 198.018 184.910 194.224 1.00 223.20 ? 705  THR C CA  1 
ATOM   10883 C C   . THR B 2 687 ? 198.150 185.041 192.728 1.00 223.20 ? 705  THR C C   1 
ATOM   10884 O O   . THR B 2 687 ? 198.815 185.959 192.241 1.00 223.20 ? 705  THR C O   1 
ATOM   10885 C CB  . THR B 2 687 ? 196.572 185.152 194.678 1.00 312.09 ? 705  THR C CB  1 
ATOM   10886 O OG1 . THR B 2 687 ? 196.103 186.488 194.347 1.00 312.09 ? 705  THR C OG1 1 
ATOM   10887 C CG2 . THR B 2 687 ? 196.586 185.001 196.112 1.00 312.09 ? 705  THR C CG2 1 
ATOM   10888 N N   . GLY B 2 688 ? 197.527 184.119 191.984 1.00 215.62 ? 706  GLY C N   1 
ATOM   10889 C CA  . GLY B 2 688 ? 197.657 184.200 190.528 1.00 215.62 ? 706  GLY C CA  1 
ATOM   10890 C C   . GLY B 2 688 ? 197.235 182.957 189.745 1.00 215.62 ? 706  GLY C C   1 
ATOM   10891 O O   . GLY B 2 688 ? 196.453 182.120 190.203 1.00 215.62 ? 706  GLY C O   1 
ATOM   10892 N N   . LYS B 2 689 ? 197.681 182.898 188.494 1.00 204.20 ? 707  LYS C N   1 
ATOM   10893 C CA  . LYS B 2 689 ? 197.363 181.794 187.596 1.00 204.20 ? 707  LYS C CA  1 
ATOM   10894 C C   . LYS B 2 689 ? 198.632 181.141 187.046 1.00 204.20 ? 707  LYS C C   1 
ATOM   10895 O O   . LYS B 2 689 ? 198.631 180.544 185.961 1.00 204.20 ? 707  LYS C O   1 
ATOM   10896 C CB  . LYS B 2 689 ? 196.446 182.250 186.467 1.00 303.65 ? 707  LYS C CB  1 
ATOM   10897 C CG  . LYS B 2 689 ? 195.069 182.721 186.940 1.00 303.65 ? 707  LYS C CG  1 
ATOM   10898 C CD  . LYS B 2 689 ? 194.154 183.081 185.770 1.00 303.65 ? 707  LYS C CD  1 
ATOM   10899 C CE  . LYS B 2 689 ? 192.790 183.567 186.256 1.00 303.65 ? 707  LYS C CE  1 
ATOM   10900 N NZ  . LYS B 2 689 ? 191.908 183.975 185.124 1.00 303.65 ? 707  LYS C NZ  1 
ATOM   10901 N N   . GLU B 2 690 ? 199.693 181.166 187.845 1.00 209.84 ? 708  GLU C N   1 
ATOM   10902 C CA  . GLU B 2 690 ? 200.914 180.487 187.445 1.00 209.84 ? 708  GLU C CA  1 
ATOM   10903 C C   . GLU B 2 690 ? 200.552 179.108 186.935 1.00 209.84 ? 708  GLU C C   1 
ATOM   10904 O O   . GLU B 2 690 ? 201.080 178.662 185.921 1.00 209.84 ? 708  GLU C O   1 
ATOM   10905 C CB  . GLU B 2 690 ? 201.862 180.381 188.628 1.00 276.55 ? 708  GLU C CB  1 
ATOM   10906 C CG  . GLU B 2 690 ? 202.079 181.689 189.375 1.00 276.55 ? 708  GLU C CG  1 
ATOM   10907 C CD  . GLU B 2 690 ? 200.921 182.054 190.287 1.00 276.55 ? 708  GLU C CD  1 
ATOM   10908 O OE1 . GLU B 2 690 ? 200.042 181.198 190.511 1.00 276.55 ? 708  GLU C OE1 1 
ATOM   10909 O OE2 . GLU B 2 690 ? 200.894 183.197 190.787 1.00 276.55 ? 708  GLU C OE2 1 
ATOM   10910 N N   . THR B 2 691 ? 199.659 178.421 187.636 1.00 215.66 ? 709  THR C N   1 
ATOM   10911 C CA  . THR B 2 691 ? 199.184 177.116 187.172 1.00 215.66 ? 709  THR C CA  1 
ATOM   10912 C C   . THR B 2 691 ? 200.296 176.217 186.670 1.00 215.66 ? 709  THR C C   1 
ATOM   10913 O O   . THR B 2 691 ? 201.325 176.071 187.328 1.00 215.66 ? 709  THR C O   1 
ATOM   10914 C CB  . THR B 2 691 ? 198.148 177.269 186.046 1.00 301.55 ? 709  THR C CB  1 
ATOM   10915 O OG1 . THR B 2 691 ? 198.740 177.952 184.935 1.00 301.55 ? 709  THR C OG1 1 
ATOM   10916 C CG2 . THR B 2 691 ? 196.946 178.059 186.537 1.00 301.55 ? 709  THR C CG2 1 
ATOM   10917 N N   . ALA B 2 692 ? 200.087 175.609 185.505 1.00 215.74 ? 710  ALA C N   1 
ATOM   10918 C CA  . ALA B 2 692 ? 201.096 174.714 184.936 1.00 215.74 ? 710  ALA C CA  1 
ATOM   10919 C C   . ALA B 2 692 ? 200.952 174.522 183.431 1.00 215.74 ? 710  ALA C C   1 
ATOM   10920 O O   . ALA B 2 692 ? 199.837 174.442 182.919 1.00 215.74 ? 710  ALA C O   1 
ATOM   10921 C CB  . ALA B 2 692 ? 201.041 173.360 185.636 1.00 291.45 ? 710  ALA C CB  1 
ATOM   10922 N N   . PRO B 2 693 ? 202.068 174.508 182.673 1.00 208.28 ? 711  PRO C N   1 
ATOM   10923 C CA  . PRO B 2 693 ? 201.977 174.180 181.258 1.00 208.28 ? 711  PRO C CA  1 
ATOM   10924 C C   . PRO B 2 693 ? 201.255 172.832 181.090 1.00 208.28 ? 711  PRO C C   1 
ATOM   10925 O O   . PRO B 2 693 ? 200.817 172.487 179.993 1.00 208.28 ? 711  PRO C O   1 
ATOM   10926 C CB  . PRO B 2 693 ? 203.420 174.192 180.745 1.00 355.90 ? 711  PRO C CB  1 
ATOM   10927 C CG  . PRO B 2 693 ? 204.261 173.931 181.992 1.00 355.90 ? 711  PRO C CG  1 
ATOM   10928 C CD  . PRO B 2 693 ? 203.455 174.597 183.100 1.00 355.90 ? 711  PRO C CD  1 
ATOM   10929 N N   . GLU B 2 694 ? 201.083 172.106 182.203 1.00 208.13 ? 712  GLU C N   1 
ATOM   10930 C CA  . GLU B 2 694 ? 200.367 170.863 182.282 1.00 208.13 ? 712  GLU C CA  1 
ATOM   10931 C C   . GLU B 2 694 ? 198.993 171.222 182.766 1.00 208.13 ? 712  GLU C C   1 
ATOM   10932 O O   . GLU B 2 694 ? 198.835 172.246 183.420 1.00 208.13 ? 712  GLU C O   1 
ATOM   10933 C CB  . GLU B 2 694 ? 201.027 169.910 183.267 1.00 274.30 ? 712  GLU C CB  1 
ATOM   10934 C CG  . GLU B 2 694 ? 202.420 169.483 182.889 1.00 274.30 ? 712  GLU C CG  1 
ATOM   10935 C CD  . GLU B 2 694 ? 203.002 168.530 183.878 1.00 274.30 ? 712  GLU C CD  1 
ATOM   10936 O OE1 . GLU B 2 694 ? 202.364 168.289 184.875 1.00 274.30 ? 712  GLU C OE1 1 
ATOM   10937 O OE2 . GLU B 2 694 ? 204.080 168.042 183.647 1.00 274.30 ? 712  GLU C OE2 1 
ATOM   10938 N N   . ARG B 2 695 ? 197.992 170.402 182.460 1.00 206.76 ? 713  ARG C N   1 
ATOM   10939 C CA  . ARG B 2 695 ? 196.603 170.581 182.917 1.00 206.76 ? 713  ARG C CA  1 
ATOM   10940 C C   . ARG B 2 695 ? 195.925 171.752 182.196 1.00 206.76 ? 713  ARG C C   1 
ATOM   10941 O O   . ARG B 2 695 ? 194.893 171.581 181.547 1.00 206.76 ? 713  ARG C O   1 
ATOM   10942 C CB  . ARG B 2 695 ? 196.542 170.850 184.418 1.00 302.28 ? 713  ARG C CB  1 
ATOM   10943 C CG  . ARG B 2 695 ? 197.054 169.740 185.299 1.00 302.28 ? 713  ARG C CG  1 
ATOM   10944 C CD  . ARG B 2 695 ? 197.035 170.149 186.719 1.00 302.28 ? 713  ARG C CD  1 
ATOM   10945 N NE  . ARG B 2 695 ? 197.643 169.150 187.585 1.00 302.28 ? 713  ARG C NE  1 
ATOM   10946 C CZ  . ARG B 2 695 ? 197.773 169.263 188.928 1.00 302.28 ? 713  ARG C CZ  1 
ATOM   10947 N NH1 . ARG B 2 695 ? 198.359 168.326 189.631 1.00 302.28 ? 713  ARG C NH1 1 
ATOM   10948 N NH2 . ARG B 2 695 ? 197.324 170.307 189.578 1.00 302.28 ? 713  ARG C NH2 1 
ATOM   10949 N N   . ARG B 2 696 ? 196.537 172.939 182.193 1.00 203.23 ? 714  ARG C N   1 
ATOM   10950 C CA  . ARG B 2 696 ? 196.102 174.210 181.589 1.00 203.23 ? 714  ARG C CA  1 
ATOM   10951 C C   . ARG B 2 696 ? 194.796 174.775 182.135 1.00 203.23 ? 714  ARG C C   1 
ATOM   10952 O O   . ARG B 2 696 ? 194.758 175.955 182.466 1.00 203.23 ? 714  ARG C O   1 
ATOM   10953 C CB  . ARG B 2 696 ? 196.079 174.120 180.059 1.00 285.42 ? 714  ARG C CB  1 
ATOM   10954 C CG  . ARG B 2 696 ? 197.443 173.834 179.422 1.00 285.42 ? 714  ARG C CG  1 
ATOM   10955 C CD  . ARG B 2 696 ? 198.405 175.016 179.554 1.00 285.42 ? 714  ARG C CD  1 
ATOM   10956 N NE  . ARG B 2 696 ? 199.612 174.785 178.745 1.00 285.42 ? 714  ARG C NE  1 
ATOM   10957 C CZ  . ARG B 2 696 ? 200.212 175.616 177.913 1.00 285.42 ? 714  ARG C CZ  1 
ATOM   10958 N NH1 . ARG B 2 696 ? 201.270 175.234 177.262 1.00 285.42 ? 714  ARG C NH1 1 
ATOM   10959 N NH2 . ARG B 2 696 ? 199.795 176.831 177.714 1.00 285.42 ? 714  ARG C NH2 1 
ATOM   10960 N N   . GLU B 2 697 ? 193.736 173.986 182.282 1.00 199.67 ? 715  GLU C N   1 
ATOM   10961 C CA  . GLU B 2 697 ? 192.474 174.507 182.817 1.00 199.67 ? 715  GLU C CA  1 
ATOM   10962 C C   . GLU B 2 697 ? 192.444 174.470 184.336 1.00 199.67 ? 715  GLU C C   1 
ATOM   10963 O O   . GLU B 2 697 ? 191.704 173.706 184.957 1.00 199.67 ? 715  GLU C O   1 
ATOM   10964 C CB  . GLU B 2 697 ? 191.287 173.740 182.260 1.00 263.15 ? 715  GLU C CB  1 
ATOM   10965 C CG  . GLU B 2 697 ? 191.078 173.980 180.813 1.00 263.15 ? 715  GLU C CG  1 
ATOM   10966 C CD  . GLU B 2 697 ? 190.624 175.367 180.531 1.00 263.15 ? 715  GLU C CD  1 
ATOM   10967 O OE1 . GLU B 2 697 ? 190.118 175.993 181.421 1.00 263.15 ? 715  GLU C OE1 1 
ATOM   10968 O OE2 . GLU B 2 697 ? 190.818 175.826 179.432 1.00 263.15 ? 715  GLU C OE2 1 
ATOM   10969 N N   . VAL B 2 698 ? 193.292 175.308 184.909 1.00 204.75 ? 716  VAL C N   1 
ATOM   10970 C CA  . VAL B 2 698 ? 193.486 175.462 186.336 1.00 204.75 ? 716  VAL C CA  1 
ATOM   10971 C C   . VAL B 2 698 ? 193.184 176.930 186.616 1.00 204.75 ? 716  VAL C C   1 
ATOM   10972 O O   . VAL B 2 698 ? 193.834 177.803 186.042 1.00 204.75 ? 716  VAL C O   1 
ATOM   10973 C CB  . VAL B 2 698 ? 194.942 175.111 186.680 1.00 296.75 ? 716  VAL C CB  1 
ATOM   10974 C CG1 . VAL B 2 698 ? 195.178 175.239 188.170 1.00 296.75 ? 716  VAL C CG1 1 
ATOM   10975 C CG2 . VAL B 2 698 ? 195.271 173.714 186.176 1.00 296.75 ? 716  VAL C CG2 1 
ATOM   10976 N N   . VAL B 2 699 ? 192.180 177.226 187.437 1.00 197.05 ? 717  VAL C N   1 
ATOM   10977 C CA  . VAL B 2 699 ? 191.791 178.624 187.570 1.00 197.05 ? 717  VAL C CA  1 
ATOM   10978 C C   . VAL B 2 699 ? 191.721 179.201 188.980 1.00 197.05 ? 717  VAL C C   1 
ATOM   10979 O O   . VAL B 2 699 ? 190.994 178.688 189.835 1.00 197.05 ? 717  VAL C O   1 
ATOM   10980 C CB  . VAL B 2 699 ? 190.415 178.810 186.875 1.00 277.49 ? 717  VAL C CB  1 
ATOM   10981 C CG1 . VAL B 2 699 ? 189.927 180.251 186.996 1.00 277.49 ? 717  VAL C CG1 1 
ATOM   10982 C CG2 . VAL B 2 699 ? 190.532 178.412 185.392 1.00 277.49 ? 717  VAL C CG2 1 
ATOM   10983 N N   . THR B 2 700 ? 192.418 180.331 189.153 1.00 203.76 ? 718  THR C N   1 
ATOM   10984 C CA  . THR B 2 700 ? 192.451 181.151 190.372 1.00 203.76 ? 718  THR C CA  1 
ATOM   10985 C C   . THR B 2 700 ? 193.100 180.488 191.597 1.00 203.76 ? 718  THR C C   1 
ATOM   10986 O O   . THR B 2 700 ? 192.431 179.864 192.424 1.00 203.76 ? 718  THR C O   1 
ATOM   10987 C CB  . THR B 2 700 ? 191.027 181.677 190.681 1.00 278.93 ? 718  THR C CB  1 
ATOM   10988 O OG1 . THR B 2 700 ? 190.547 182.425 189.549 1.00 278.93 ? 718  THR C OG1 1 
ATOM   10989 C CG2 . THR B 2 700 ? 191.046 182.589 191.860 1.00 278.93 ? 718  THR C CG2 1 
ATOM   10990 N N   . LEU B 2 701 ? 194.423 180.625 191.703 1.00 200.31 ? 719  LEU C N   1 
ATOM   10991 C CA  . LEU B 2 701 ? 195.197 179.998 192.762 1.00 200.31 ? 719  LEU C CA  1 
ATOM   10992 C C   . LEU B 2 701 ? 195.425 180.877 193.983 1.00 200.31 ? 719  LEU C C   1 
ATOM   10993 O O   . LEU B 2 701 ? 195.504 182.106 193.897 1.00 200.31 ? 719  LEU C O   1 
ATOM   10994 C CB  . LEU B 2 701 ? 196.588 179.645 192.261 1.00 294.21 ? 719  LEU C CB  1 
ATOM   10995 C CG  . LEU B 2 701 ? 196.712 178.746 191.056 1.00 294.21 ? 719  LEU C CG  1 
ATOM   10996 C CD1 . LEU B 2 701 ? 198.187 178.653 190.756 1.00 294.21 ? 719  LEU C CD1 1 
ATOM   10997 C CD2 . LEU B 2 701 ? 196.077 177.366 191.323 1.00 294.21 ? 719  LEU C CD2 1 
ATOM   10998 N N   . ARG B 2 702 ? 195.641 180.201 195.108 1.00 191.14 ? 720  ARG C N   1 
ATOM   10999 C CA  . ARG B 2 702 ? 195.975 180.780 196.406 1.00 191.14 ? 720  ARG C CA  1 
ATOM   11000 C C   . ARG B 2 702 ? 197.466 181.082 196.323 1.00 191.14 ? 720  ARG C C   1 
ATOM   11001 O O   . ARG B 2 702 ? 198.118 180.547 195.428 1.00 191.14 ? 720  ARG C O   1 
ATOM   11002 C CB  . ARG B 2 702 ? 195.608 179.813 197.526 1.00 279.44 ? 720  ARG C CB  1 
ATOM   11003 C CG  . ARG B 2 702 ? 195.667 180.338 198.983 1.00 279.44 ? 720  ARG C CG  1 
ATOM   11004 C CD  . ARG B 2 702 ? 194.570 181.354 199.270 1.00 279.44 ? 720  ARG C CD  1 
ATOM   11005 N NE  . ARG B 2 702 ? 193.241 180.764 199.078 1.00 279.44 ? 720  ARG C NE  1 
ATOM   11006 C CZ  . ARG B 2 702 ? 192.072 181.446 199.003 1.00 279.44 ? 720  ARG C CZ  1 
ATOM   11007 N NH1 . ARG B 2 702 ? 190.953 180.848 198.742 1.00 279.44 ? 720  ARG C NH1 1 
ATOM   11008 N NH2 . ARG B 2 702 ? 191.996 182.716 199.158 1.00 279.44 ? 720  ARG C NH2 1 
ATOM   11009 N N   . CYS B 2 703 ? 198.001 181.962 197.205 1.00 198.98 ? 721  CYS C N   1 
ATOM   11010 C CA  . CYS B 2 703 ? 199.374 182.468 197.143 1.00 198.98 ? 721  CYS C CA  1 
ATOM   11011 C C   . CYS B 2 703 ? 200.432 181.385 196.991 1.00 198.98 ? 721  CYS C C   1 
ATOM   11012 O O   . CYS B 2 703 ? 200.449 180.337 197.656 1.00 198.98 ? 721  CYS C O   1 
ATOM   11013 C CB  . CYS B 2 703 ? 199.729 183.341 198.365 1.00 257.85 ? 721  CYS C CB  1 
ATOM   11014 S SG  . CYS B 2 703 ? 198.801 184.826 198.534 1.00 257.85 ? 721  CYS C SG  1 
ATOM   11015 N N   . ASN B 2 704 ? 201.386 181.706 196.138 1.00 198.02 ? 722  ASN C N   1 
ATOM   11016 C CA  . ASN B 2 704 ? 202.417 180.780 195.723 1.00 198.02 ? 722  ASN C CA  1 
ATOM   11017 C C   . ASN B 2 704 ? 203.539 180.552 196.715 1.00 198.02 ? 722  ASN C C   1 
ATOM   11018 O O   . ASN B 2 704 ? 204.689 180.936 196.508 1.00 198.02 ? 722  ASN C O   1 
ATOM   11019 C CB  . ASN B 2 704 ? 202.959 181.258 194.395 1.00 267.62 ? 722  ASN C CB  1 
ATOM   11020 C CG  . ASN B 2 704 ? 201.924 181.142 193.276 1.00 267.62 ? 722  ASN C CG  1 
ATOM   11021 O OD1 . ASN B 2 704 ? 201.328 180.080 193.041 1.00 267.62 ? 722  ASN C OD1 1 
ATOM   11022 N ND2 . ASN B 2 704 ? 201.692 182.237 192.609 1.00 267.62 ? 722  ASN C ND2 1 
ATOM   11023 N N   . HIS B 2 705 ? 203.164 179.843 197.769 1.00 196.07 ? 723  HIS C N   1 
ATOM   11024 C CA  . HIS B 2 705 ? 204.010 179.427 198.881 1.00 196.07 ? 723  HIS C CA  1 
ATOM   11025 C C   . HIS B 2 705 ? 203.855 177.937 199.078 1.00 196.07 ? 723  HIS C C   1 
ATOM   11026 O O   . HIS B 2 705 ? 203.682 177.430 200.202 1.00 196.07 ? 723  HIS C O   1 
ATOM   11027 C CB  . HIS B 2 705 ? 203.669 180.199 200.140 1.00 266.63 ? 723  HIS C CB  1 
ATOM   11028 C CG  . HIS B 2 705 ? 203.974 181.612 199.977 1.00 266.63 ? 723  HIS C CG  1 
ATOM   11029 N ND1 . HIS B 2 705 ? 205.246 182.115 200.112 1.00 266.63 ? 723  HIS C ND1 1 
ATOM   11030 C CD2 . HIS B 2 705 ? 203.196 182.637 199.631 1.00 266.63 ? 723  HIS C CD2 1 
ATOM   11031 C CE1 . HIS B 2 705 ? 205.232 183.400 199.870 1.00 266.63 ? 723  HIS C CE1 1 
ATOM   11032 N NE2 . HIS B 2 705 ? 203.991 183.755 199.565 1.00 266.63 ? 723  HIS C NE2 1 
ATOM   11033 N N   . ARG B 2 706 ? 203.849 177.239 197.948 1.00 194.50 ? 724  ARG C N   1 
ATOM   11034 C CA  . ARG B 2 706 ? 203.717 175.814 197.965 1.00 194.50 ? 724  ARG C CA  1 
ATOM   11035 C C   . ARG B 2 706 ? 204.885 175.196 198.654 1.00 194.50 ? 724  ARG C C   1 
ATOM   11036 O O   . ARG B 2 706 ? 206.040 175.489 198.351 1.00 194.50 ? 724  ARG C O   1 
ATOM   11037 C CB  . ARG B 2 706 ? 203.602 175.251 196.561 1.00 273.16 ? 724  ARG C CB  1 
ATOM   11038 C CG  . ARG B 2 706 ? 203.569 173.769 196.559 1.00 273.16 ? 724  ARG C CG  1 
ATOM   11039 C CD  . ARG B 2 706 ? 203.263 173.146 195.292 1.00 273.16 ? 724  ARG C CD  1 
ATOM   11040 N NE  . ARG B 2 706 ? 203.503 171.710 195.396 1.00 273.16 ? 724  ARG C NE  1 
ATOM   11041 C CZ  . ARG B 2 706 ? 203.185 170.793 194.470 1.00 273.16 ? 724  ARG C CZ  1 
ATOM   11042 N NH1 . ARG B 2 706 ? 203.487 169.523 194.683 1.00 273.16 ? 724  ARG C NH1 1 
ATOM   11043 N NH2 . ARG B 2 706 ? 202.585 171.152 193.356 1.00 273.16 ? 724  ARG C NH2 1 
ATOM   11044 N N   . ASP B 2 707 ? 204.560 174.347 199.608 1.00 192.35 ? 725  ASP C N   1 
ATOM   11045 C CA  . ASP B 2 707 ? 205.509 173.611 200.396 1.00 192.35 ? 725  ASP C CA  1 
ATOM   11046 C C   . ASP B 2 707 ? 206.543 174.562 201.008 1.00 192.35 ? 725  ASP C C   1 
ATOM   11047 O O   . ASP B 2 707 ? 207.713 174.198 201.162 1.00 192.35 ? 725  ASP C O   1 
ATOM   11048 C CB  . ASP B 2 707 ? 206.191 172.570 199.501 1.00 246.88 ? 725  ASP C CB  1 
ATOM   11049 C CG  . ASP B 2 707 ? 205.168 171.610 198.769 1.00 246.88 ? 725  ASP C CG  1 
ATOM   11050 O OD1 . ASP B 2 707 ? 204.113 171.309 199.271 1.00 246.88 ? 725  ASP C OD1 1 
ATOM   11051 O OD2 . ASP B 2 707 ? 205.459 171.236 197.658 1.00 246.88 ? 725  ASP C OD2 1 
ATOM   11052 N N   . ALA B 2 708 ? 206.127 175.765 201.414 1.00 183.71 ? 726  ALA C N   1 
ATOM   11053 C CA  . ALA B 2 708 ? 207.088 176.663 202.007 1.00 183.71 ? 726  ALA C CA  1 
ATOM   11054 C C   . ALA B 2 708 ? 207.315 176.262 203.439 1.00 183.71 ? 726  ALA C C   1 
ATOM   11055 O O   . ALA B 2 708 ? 206.410 176.367 204.266 1.00 183.71 ? 726  ALA C O   1 
ATOM   11056 C CB  . ALA B 2 708 ? 206.614 178.095 201.918 1.00 248.18 ? 726  ALA C CB  1 
ATOM   11057 N N   . SER B 2 709 ? 208.575 176.014 203.772 1.00 178.77 ? 727  SER C N   1 
ATOM   11058 C CA  . SER B 2 709 ? 209.037 175.524 205.069 1.00 178.77 ? 727  SER C CA  1 
ATOM   11059 C C   . SER B 2 709 ? 208.743 176.457 206.223 1.00 178.77 ? 727  SER C C   1 
ATOM   11060 O O   . SER B 2 709 ? 208.812 176.068 207.390 1.00 178.77 ? 727  SER C O   1 
ATOM   11061 C CB  . SER B 2 709 ? 210.520 175.267 204.996 1.00 239.63 ? 727  SER C CB  1 
ATOM   11062 O OG  . SER B 2 709 ? 211.215 176.464 204.806 1.00 239.63 ? 727  SER C OG  1 
ATOM   11063 N N   . MET B 2 710 ? 208.346 177.677 205.907 1.00 177.75 ? 728  MET C N   1 
ATOM   11064 C CA  . MET B 2 710 ? 207.963 178.653 206.903 1.00 177.75 ? 728  MET C CA  1 
ATOM   11065 C C   . MET B 2 710 ? 206.748 178.129 207.673 1.00 177.75 ? 728  MET C C   1 
ATOM   11066 O O   . MET B 2 710 ? 206.527 178.506 208.824 1.00 177.75 ? 728  MET C O   1 
ATOM   11067 C CB  . MET B 2 710 ? 207.638 179.986 206.243 1.00 254.00 ? 728  MET C CB  1 
ATOM   11068 C CG  . MET B 2 710 ? 208.832 180.734 205.675 1.00 254.00 ? 728  MET C CG  1 
ATOM   11069 S SD  . MET B 2 710 ? 210.077 181.135 206.927 1.00 254.00 ? 728  MET C SD  1 
ATOM   11070 C CE  . MET B 2 710 ? 209.210 182.326 207.940 1.00 254.00 ? 728  MET C CE  1 
ATOM   11071 N N   . LEU B 2 711 ? 206.000 177.196 207.065 1.00 179.43 ? 729  LEU C N   1 
ATOM   11072 C CA  . LEU B 2 711 ? 204.816 176.583 207.650 1.00 179.43 ? 729  LEU C CA  1 
ATOM   11073 C C   . LEU B 2 711 ? 205.193 175.759 208.863 1.00 179.43 ? 729  LEU C C   1 
ATOM   11074 O O   . LEU B 2 711 ? 204.360 175.492 209.738 1.00 179.43 ? 729  LEU C O   1 
ATOM   11075 C CB  . LEU B 2 711 ? 204.089 175.692 206.618 1.00 255.03 ? 729  LEU C CB  1 
ATOM   11076 C CG  . LEU B 2 711 ? 204.806 174.366 206.129 1.00 255.03 ? 729  LEU C CG  1 
ATOM   11077 C CD1 . LEU B 2 711 ? 204.485 173.150 207.064 1.00 255.03 ? 729  LEU C CD1 1 
ATOM   11078 C CD2 . LEU B 2 711 ? 204.336 174.044 204.683 1.00 255.03 ? 729  LEU C CD2 1 
ATOM   11079 N N   . GLY B 2 712 ? 206.448 175.337 208.931 1.00 182.89 ? 730  GLY C N   1 
ATOM   11080 C CA  . GLY B 2 712 ? 206.910 174.532 210.027 1.00 182.89 ? 730  GLY C CA  1 
ATOM   11081 C C   . GLY B 2 712 ? 206.884 175.344 211.310 1.00 182.89 ? 730  GLY C C   1 
ATOM   11082 O O   . GLY B 2 712 ? 206.884 174.772 212.402 1.00 182.89 ? 730  GLY C O   1 
ATOM   11083 N N   . SER B 2 713 ? 206.830 176.678 211.196 1.00 179.03 ? 731  SER C N   1 
ATOM   11084 C CA  . SER B 2 713 ? 206.782 177.538 212.358 1.00 179.03 ? 731  SER C CA  1 
ATOM   11085 C C   . SER B 2 713 ? 205.418 177.472 213.017 1.00 179.03 ? 731  SER C C   1 
ATOM   11086 O O   . SER B 2 713 ? 205.269 177.806 214.192 1.00 179.03 ? 731  SER C O   1 
ATOM   11087 C CB  . SER B 2 713 ? 207.075 178.965 211.974 1.00 238.46 ? 731  SER C CB  1 
ATOM   11088 O OG  . SER B 2 713 ? 206.043 179.510 211.206 1.00 238.46 ? 731  SER C OG  1 
ATOM   11089 N N   . LEU B 2 714 ? 204.413 177.014 212.282 1.00 174.25 ? 732  LEU C N   1 
ATOM   11090 C CA  . LEU B 2 714 ? 203.082 176.945 212.825 1.00 174.25 ? 732  LEU C CA  1 
ATOM   11091 C C   . LEU B 2 714 ? 203.014 175.635 213.556 1.00 174.25 ? 732  LEU C C   1 
ATOM   11092 O O   . LEU B 2 714 ? 202.435 175.535 214.640 1.00 174.25 ? 732  LEU C O   1 
ATOM   11093 C CB  . LEU B 2 714 ? 202.093 176.969 211.677 1.00 255.93 ? 732  LEU C CB  1 
ATOM   11094 C CG  . LEU B 2 714 ? 202.145 178.226 210.802 1.00 255.93 ? 732  LEU C CG  1 
ATOM   11095 C CD1 . LEU B 2 714 ? 201.341 177.982 209.648 1.00 255.93 ? 732  LEU C CD1 1 
ATOM   11096 C CD2 . LEU B 2 714 ? 201.586 179.451 211.523 1.00 255.93 ? 732  LEU C CD2 1 
ATOM   11097 N N   . ALA B 2 715 ? 203.655 174.621 212.960 1.00 182.42 ? 733  ALA C N   1 
ATOM   11098 C CA  . ALA B 2 715 ? 203.671 173.318 213.593 1.00 182.42 ? 733  ALA C CA  1 
ATOM   11099 C C   . ALA B 2 715 ? 204.396 173.453 214.913 1.00 182.42 ? 733  ALA C C   1 
ATOM   11100 O O   . ALA B 2 715 ? 203.965 172.906 215.935 1.00 182.42 ? 733  ALA C O   1 
ATOM   11101 C CB  . ALA B 2 715 ? 204.346 172.292 212.701 1.00 246.44 ? 733  ALA C CB  1 
ATOM   11102 N N   . TYR B 2 716 ? 205.455 174.253 214.893 1.00 186.99 ? 734  TYR C N   1 
ATOM   11103 C CA  . TYR B 2 716 ? 206.231 174.566 216.055 1.00 186.99 ? 734  TYR C CA  1 
ATOM   11104 C C   . TYR B 2 716 ? 205.402 175.212 217.106 1.00 186.99 ? 734  TYR C C   1 
ATOM   11105 O O   . TYR B 2 716 ? 205.383 174.772 218.243 1.00 186.99 ? 734  TYR C O   1 
ATOM   11106 C CB  . TYR B 2 716 ? 207.390 175.460 215.715 1.00 259.15 ? 734  TYR C CB  1 
ATOM   11107 C CG  . TYR B 2 716 ? 208.032 176.044 216.911 1.00 259.15 ? 734  TYR C CG  1 
ATOM   11108 C CD1 . TYR B 2 716 ? 208.836 175.294 217.738 1.00 259.15 ? 734  TYR C CD1 1 
ATOM   11109 C CD2 . TYR B 2 716 ? 207.818 177.381 217.171 1.00 259.15 ? 734  TYR C CD2 1 
ATOM   11110 C CE1 . TYR B 2 716 ? 209.426 175.894 218.824 1.00 259.15 ? 734  TYR C CE1 1 
ATOM   11111 C CE2 . TYR B 2 716 ? 208.402 177.973 218.242 1.00 259.15 ? 734  TYR C CE2 1 
ATOM   11112 C CZ  . TYR B 2 716 ? 209.207 177.248 219.066 1.00 259.15 ? 734  TYR C CZ  1 
ATOM   11113 O OH  . TYR B 2 716 ? 209.810 177.860 220.143 1.00 259.15 ? 734  TYR C OH  1 
ATOM   11114 N N   . ASN B 2 717 ? 204.638 176.226 216.737 1.00 180.45 ? 735  ASN C N   1 
ATOM   11115 C CA  . ASN B 2 717 ? 203.872 176.911 217.746 1.00 180.45 ? 735  ASN C CA  1 
ATOM   11116 C C   . ASN B 2 717 ? 202.959 175.949 218.488 1.00 180.45 ? 735  ASN C C   1 
ATOM   11117 O O   . ASN B 2 717 ? 202.716 176.115 219.685 1.00 180.45 ? 735  ASN C O   1 
ATOM   11118 C CB  . ASN B 2 717 ? 203.030 177.979 217.106 1.00 243.88 ? 735  ASN C CB  1 
ATOM   11119 C CG  . ASN B 2 717 ? 203.848 179.060 216.584 1.00 243.88 ? 735  ASN C CG  1 
ATOM   11120 O OD1 . ASN B 2 717 ? 205.044 179.139 216.868 1.00 243.88 ? 735  ASN C OD1 1 
ATOM   11121 N ND2 . ASN B 2 717 ? 203.253 179.923 215.829 1.00 243.88 ? 735  ASN C ND2 1 
ATOM   11122 N N   . VAL B 2 718 ? 202.449 174.931 217.802 1.00 181.76 ? 736  VAL C N   1 
ATOM   11123 C CA  . VAL B 2 718 ? 201.584 173.999 218.491 1.00 181.76 ? 736  VAL C CA  1 
ATOM   11124 C C   . VAL B 2 718 ? 202.386 173.050 219.380 1.00 181.76 ? 736  VAL C C   1 
ATOM   11125 O O   . VAL B 2 718 ? 202.045 172.900 220.559 1.00 181.76 ? 736  VAL C O   1 
ATOM   11126 C CB  . VAL B 2 718 ? 200.745 173.187 217.502 1.00 263.43 ? 736  VAL C CB  1 
ATOM   11127 C CG1 . VAL B 2 718 ? 199.905 172.126 218.260 1.00 263.43 ? 736  VAL C CG1 1 
ATOM   11128 C CG2 . VAL B 2 718 ? 199.887 174.131 216.720 1.00 263.43 ? 736  VAL C CG2 1 
ATOM   11129 N N   . LEU B 2 719 ? 203.471 172.470 218.830 1.00 193.14 ? 737  LEU C N   1 
ATOM   11130 C CA  . LEU B 2 719 ? 204.337 171.480 219.497 1.00 193.14 ? 737  LEU C CA  1 
ATOM   11131 C C   . LEU B 2 719 ? 205.093 172.064 220.657 1.00 193.14 ? 737  LEU C C   1 
ATOM   11132 O O   . LEU B 2 719 ? 205.375 171.379 221.657 1.00 193.14 ? 737  LEU C O   1 
ATOM   11133 C CB  . LEU B 2 719 ? 205.270 170.832 218.474 1.00 283.68 ? 737  LEU C CB  1 
ATOM   11134 C CG  . LEU B 2 719 ? 204.546 169.903 217.463 1.00 283.68 ? 737  LEU C CG  1 
ATOM   11135 C CD1 . LEU B 2 719 ? 205.500 169.497 216.349 1.00 283.68 ? 737  LEU C CD1 1 
ATOM   11136 C CD2 . LEU B 2 719 ? 204.023 168.618 218.202 1.00 283.68 ? 737  LEU C CD2 1 
ATOM   11137 N N   . LEU B 2 720 ? 205.285 173.363 220.592 1.00 196.58 ? 738  LEU C N   1 
ATOM   11138 C CA  . LEU B 2 720 ? 205.899 174.130 221.630 1.00 196.58 ? 738  LEU C CA  1 
ATOM   11139 C C   . LEU B 2 720 ? 205.169 173.865 222.937 1.00 196.58 ? 738  LEU C C   1 
ATOM   11140 O O   . LEU B 2 720 ? 205.784 173.925 224.001 1.00 196.58 ? 738  LEU C O   1 
ATOM   11141 C CB  . LEU B 2 720 ? 205.855 175.604 221.239 1.00 288.73 ? 738  LEU C CB  1 
ATOM   11142 C CG  . LEU B 2 720 ? 206.431 176.624 222.203 1.00 288.73 ? 738  LEU C CG  1 
ATOM   11143 C CD1 . LEU B 2 720 ? 207.907 176.328 222.481 1.00 288.73 ? 738  LEU C CD1 1 
ATOM   11144 C CD2 . LEU B 2 720 ? 206.250 178.008 221.548 1.00 288.73 ? 738  LEU C CD2 1 
ATOM   11145 N N   . ILE B 2 721 ? 203.847 173.667 222.898 1.00 200.20 ? 739  ILE C N   1 
ATOM   11146 C CA  . ILE B 2 721 ? 203.154 173.341 224.115 1.00 200.20 ? 739  ILE C CA  1 
ATOM   11147 C C   . ILE B 2 721 ? 202.828 171.840 224.069 1.00 200.20 ? 739  ILE C C   1 
ATOM   11148 O O   . ILE B 2 721 ? 202.985 171.121 225.054 1.00 200.20 ? 739  ILE C O   1 
ATOM   11149 C CB  . ILE B 2 721 ? 201.873 174.169 224.313 1.00 295.05 ? 739  ILE C CB  1 
ATOM   11150 C CG1 . ILE B 2 721 ? 202.241 175.667 224.378 1.00 295.05 ? 739  ILE C CG1 1 
ATOM   11151 C CG2 . ILE B 2 721 ? 201.213 173.746 225.647 1.00 295.05 ? 739  ILE C CG2 1 
ATOM   11152 C CD1 . ILE B 2 721 ? 201.062 176.616 224.358 1.00 295.05 ? 739  ILE C CD1 1 
ATOM   11153 N N   . ALA B 2 722 ? 202.326 171.370 222.925 1.00 207.20 ? 740  ALA C N   1 
ATOM   11154 C CA  . ALA B 2 722 ? 201.819 170.007 222.790 1.00 207.20 ? 740  ALA C CA  1 
ATOM   11155 C C   . ALA B 2 722 ? 202.774 168.845 223.000 1.00 207.20 ? 740  ALA C C   1 
ATOM   11156 O O   . ALA B 2 722 ? 202.333 167.783 223.432 1.00 207.20 ? 740  ALA C O   1 
ATOM   11157 C CB  . ALA B 2 722 ? 201.174 169.857 221.425 1.00 279.92 ? 740  ALA C CB  1 
ATOM   11158 N N   . LEU B 2 723 ? 204.035 168.973 222.643 1.00 210.74 ? 741  LEU C N   1 
ATOM   11159 C CA  . LEU B 2 723 ? 204.938 167.850 222.811 1.00 210.74 ? 741  LEU C CA  1 
ATOM   11160 C C   . LEU B 2 723 ? 205.995 168.173 223.853 1.00 210.74 ? 741  LEU C C   1 
ATOM   11161 O O   . LEU B 2 723 ? 206.369 167.351 224.697 1.00 210.74 ? 741  LEU C O   1 
ATOM   11162 C CB  . LEU B 2 723 ? 205.562 167.526 221.450 1.00 309.53 ? 741  LEU C CB  1 
ATOM   11163 C CG  . LEU B 2 723 ? 206.520 166.324 221.332 1.00 309.53 ? 741  LEU C CG  1 
ATOM   11164 C CD1 . LEU B 2 723 ? 205.788 165.026 221.685 1.00 309.53 ? 741  LEU C CD1 1 
ATOM   11165 C CD2 . LEU B 2 723 ? 207.031 166.265 219.895 1.00 309.53 ? 741  LEU C CD2 1 
ATOM   11166 N N   . CYS B 2 724 ? 206.427 169.420 223.828 1.00 211.87 ? 742  CYS C N   1 
ATOM   11167 C CA  . CYS B 2 724 ? 207.553 169.905 224.600 1.00 211.87 ? 742  CYS C CA  1 
ATOM   11168 C C   . CYS B 2 724 ? 207.308 170.058 226.090 1.00 211.87 ? 742  CYS C C   1 
ATOM   11169 O O   . CYS B 2 724 ? 208.247 170.367 226.830 1.00 211.87 ? 742  CYS C O   1 
ATOM   11170 C CB  . CYS B 2 724 ? 207.952 171.265 224.065 1.00 284.00 ? 742  CYS C CB  1 
ATOM   11171 S SG  . CYS B 2 724 ? 208.486 171.250 222.345 1.00 284.00 ? 742  CYS C SG  1 
ATOM   11172 N N   . THR B 2 725 ? 206.059 169.917 226.527 1.00 217.61 ? 743  THR C N   1 
ATOM   11173 C CA  . THR B 2 725 ? 205.733 170.073 227.937 1.00 217.61 ? 743  THR C CA  1 
ATOM   11174 C C   . THR B 2 725 ? 205.250 168.771 228.575 1.00 217.61 ? 743  THR C C   1 
ATOM   11175 O O   . THR B 2 725 ? 204.858 168.762 229.756 1.00 217.61 ? 743  THR C O   1 
ATOM   11176 C CB  . THR B 2 725 ? 204.660 171.142 228.197 1.00 304.28 ? 743  THR C CB  1 
ATOM   11177 O OG1 . THR B 2 725 ? 203.418 170.768 227.607 1.00 304.28 ? 743  THR C OG1 1 
ATOM   11178 C CG2 . THR B 2 725 ? 205.090 172.483 227.627 1.00 304.28 ? 743  THR C CG2 1 
ATOM   11179 N N   . LEU B 2 726 ? 205.290 167.648 227.845 1.00 216.58 ? 744  LEU C N   1 
ATOM   11180 C CA  . LEU B 2 726 ? 204.692 166.417 228.371 1.00 216.58 ? 744  LEU C CA  1 
ATOM   11181 C C   . LEU B 2 726 ? 205.541 165.659 229.370 1.00 216.58 ? 744  LEU C C   1 
ATOM   11182 O O   . LEU B 2 726 ? 205.984 164.535 229.143 1.00 216.58 ? 744  LEU C O   1 
ATOM   11183 C CB  . LEU B 2 726 ? 204.324 165.463 227.231 1.00 318.11 ? 744  LEU C CB  1 
ATOM   11184 C CG  . LEU B 2 726 ? 203.289 165.970 226.199 1.00 318.11 ? 744  LEU C CG  1 
ATOM   11185 C CD1 . LEU B 2 726 ? 203.139 164.927 225.106 1.00 318.11 ? 744  LEU C CD1 1 
ATOM   11186 C CD2 . LEU B 2 726 ? 201.929 166.230 226.858 1.00 318.11 ? 744  LEU C CD2 1 
ATOM   11187 N N   . TYR B 2 727 ? 205.721 166.312 230.503 1.00 216.86 ? 745  TYR C N   1 
ATOM   11188 C CA  . TYR B 2 727 ? 206.400 165.824 231.679 1.00 216.86 ? 745  TYR C CA  1 
ATOM   11189 C C   . TYR B 2 727 ? 205.258 165.943 232.653 1.00 216.86 ? 745  TYR C C   1 
ATOM   11190 O O   . TYR B 2 727 ? 205.102 165.221 233.639 1.00 216.86 ? 745  TYR C O   1 
ATOM   11191 C CB  . TYR B 2 727 ? 207.517 166.766 232.072 1.00 300.55 ? 745  TYR C CB  1 
ATOM   11192 C CG  . TYR B 2 727 ? 208.272 167.152 230.889 1.00 300.55 ? 745  TYR C CG  1 
ATOM   11193 C CD1 . TYR B 2 727 ? 208.950 166.242 230.114 1.00 300.55 ? 745  TYR C CD1 1 
ATOM   11194 C CD2 . TYR B 2 727 ? 208.201 168.462 230.522 1.00 300.55 ? 745  TYR C CD2 1 
ATOM   11195 C CE1 . TYR B 2 727 ? 209.554 166.676 228.957 1.00 300.55 ? 745  TYR C CE1 1 
ATOM   11196 C CE2 . TYR B 2 727 ? 208.794 168.882 229.404 1.00 300.55 ? 745  TYR C CE2 1 
ATOM   11197 C CZ  . TYR B 2 727 ? 209.461 168.001 228.605 1.00 300.55 ? 745  TYR C CZ  1 
ATOM   11198 O OH  . TYR B 2 727 ? 210.025 168.469 227.451 1.00 300.55 ? 745  TYR C OH  1 
ATOM   11199 N N   . ALA B 2 728 ? 204.390 166.892 232.284 1.00 212.69 ? 746  ALA C N   1 
ATOM   11200 C CA  . ALA B 2 728 ? 203.278 167.353 233.073 1.00 212.69 ? 746  ALA C CA  1 
ATOM   11201 C C   . ALA B 2 728 ? 202.109 166.412 232.978 1.00 212.69 ? 746  ALA C C   1 
ATOM   11202 O O   . ALA B 2 728 ? 201.118 166.583 233.669 1.00 212.69 ? 746  ALA C O   1 
ATOM   11203 C CB  . ALA B 2 728 ? 202.881 168.732 232.624 1.00 287.33 ? 746  ALA C CB  1 
ATOM   11204 N N   . PHE B 2 729 ? 202.255 165.357 232.181 1.00 202.24 ? 747  PHE C N   1 
ATOM   11205 C CA  . PHE B 2 729 ? 201.244 164.329 231.982 1.00 202.24 ? 747  PHE C CA  1 
ATOM   11206 C C   . PHE B 2 729 ? 200.945 163.666 233.321 1.00 202.24 ? 747  PHE C C   1 
ATOM   11207 O O   . PHE B 2 729 ? 199.841 163.141 233.532 1.00 202.24 ? 747  PHE C O   1 
ATOM   11208 C CB  . PHE B 2 729 ? 201.720 163.280 230.987 1.00 273.50 ? 747  PHE C CB  1 
ATOM   11209 C CG  . PHE B 2 729 ? 202.729 162.374 231.579 1.00 273.50 ? 747  PHE C CG  1 
ATOM   11210 C CD1 . PHE B 2 729 ? 202.343 161.208 232.241 1.00 273.50 ? 747  PHE C CD1 1 
ATOM   11211 C CD2 . PHE B 2 729 ? 204.059 162.677 231.502 1.00 273.50 ? 747  PHE C CD2 1 
ATOM   11212 C CE1 . PHE B 2 729 ? 203.270 160.391 232.812 1.00 273.50 ? 747  PHE C CE1 1 
ATOM   11213 C CE2 . PHE B 2 729 ? 204.987 161.863 232.073 1.00 273.50 ? 747  PHE C CE2 1 
ATOM   11214 C CZ  . PHE B 2 729 ? 204.597 160.718 232.732 1.00 273.50 ? 747  PHE C CZ  1 
ATOM   11215 N N   . LYS B 2 730 ? 201.896 163.810 234.270 1.00 197.12 ? 748  LYS C N   1 
ATOM   11216 C CA  . LYS B 2 730 ? 201.853 163.295 235.629 1.00 197.12 ? 748  LYS C CA  1 
ATOM   11217 C C   . LYS B 2 730 ? 200.655 163.876 236.385 1.00 197.12 ? 748  LYS C C   1 
ATOM   11218 O O   . LYS B 2 730 ? 200.259 163.356 237.427 1.00 197.12 ? 748  LYS C O   1 
ATOM   11219 C CB  . LYS B 2 730 ? 203.123 163.682 236.389 1.00 293.12 ? 748  LYS C CB  1 
ATOM   11220 C CG  . LYS B 2 730 ? 203.211 165.193 236.699 1.00 293.12 ? 748  LYS C CG  1 
ATOM   11221 C CD  . LYS B 2 730 ? 204.485 165.583 237.413 1.00 293.12 ? 748  LYS C CD  1 
ATOM   11222 C CE  . LYS B 2 730 ? 204.457 167.077 237.752 1.00 293.12 ? 748  LYS C CE  1 
ATOM   11223 N NZ  . LYS B 2 730 ? 205.682 167.519 238.456 1.00 293.12 ? 748  LYS C NZ  1 
ATOM   11224 N N   . THR B 2 731 ? 200.056 164.935 235.829 1.00 183.12 ? 749  THR C N   1 
ATOM   11225 C CA  . THR B 2 731 ? 198.917 165.662 236.360 1.00 183.12 ? 749  THR C CA  1 
ATOM   11226 C C   . THR B 2 731 ? 197.735 164.728 236.559 1.00 183.12 ? 749  THR C C   1 
ATOM   11227 O O   . THR B 2 731 ? 196.891 164.954 237.422 1.00 183.12 ? 749  THR C O   1 
ATOM   11228 C CB  . THR B 2 731 ? 198.537 166.799 235.385 1.00 250.67 ? 749  THR C CB  1 
ATOM   11229 O OG1 . THR B 2 731 ? 197.703 167.718 236.028 1.00 250.67 ? 749  THR C OG1 1 
ATOM   11230 C CG2 . THR B 2 731 ? 197.815 166.269 234.133 1.00 250.67 ? 749  THR C CG2 1 
ATOM   11231 N N   . ARG B 2 732 ? 197.712 163.625 235.820 1.00 181.70 ? 750  ARG C N   1 
ATOM   11232 C CA  . ARG B 2 732 ? 196.652 162.634 235.907 1.00 181.70 ? 750  ARG C CA  1 
ATOM   11233 C C   . ARG B 2 732 ? 196.600 161.961 237.271 1.00 181.70 ? 750  ARG C C   1 
ATOM   11234 O O   . ARG B 2 732 ? 195.628 161.285 237.599 1.00 181.70 ? 750  ARG C O   1 
ATOM   11235 C CB  . ARG B 2 732 ? 196.815 161.572 234.834 1.00 255.18 ? 750  ARG C CB  1 
ATOM   11236 C CG  . ARG B 2 732 ? 198.009 160.655 234.992 1.00 255.18 ? 750  ARG C CG  1 
ATOM   11237 C CD  . ARG B 2 732 ? 198.136 159.745 233.845 1.00 255.18 ? 750  ARG C CD  1 
ATOM   11238 N NE  . ARG B 2 732 ? 198.573 160.434 232.635 1.00 255.18 ? 750  ARG C NE  1 
ATOM   11239 C CZ  . ARG B 2 732 ? 198.515 159.905 231.388 1.00 255.18 ? 750  ARG C CZ  1 
ATOM   11240 N NH1 . ARG B 2 732 ? 198.950 160.595 230.351 1.00 255.18 ? 750  ARG C NH1 1 
ATOM   11241 N NH2 . ARG B 2 732 ? 198.024 158.694 231.204 1.00 255.18 ? 750  ARG C NH2 1 
ATOM   11242 N N   . LYS B 2 733 ? 197.685 162.073 238.037 1.00 190.81 ? 751  LYS C N   1 
ATOM   11243 C CA  . LYS B 2 733 ? 197.802 161.481 239.354 1.00 190.81 ? 751  LYS C CA  1 
ATOM   11244 C C   . LYS B 2 733 ? 197.408 162.471 240.456 1.00 190.81 ? 751  LYS C C   1 
ATOM   11245 O O   . LYS B 2 733 ? 197.399 162.117 241.637 1.00 190.81 ? 751  LYS C O   1 
ATOM   11246 C CB  . LYS B 2 733 ? 199.244 161.029 239.571 1.00 283.74 ? 751  LYS C CB  1 
ATOM   11247 C CG  . LYS B 2 733 ? 199.705 159.948 238.595 1.00 283.74 ? 751  LYS C CG  1 
ATOM   11248 C CD  . LYS B 2 733 ? 201.159 159.548 238.829 1.00 283.74 ? 751  LYS C CD  1 
ATOM   11249 C CE  . LYS B 2 733 ? 201.617 158.485 237.822 1.00 283.74 ? 751  LYS C CE  1 
ATOM   11250 N NZ  . LYS B 2 733 ? 203.049 158.104 238.019 1.00 283.74 ? 751  LYS C NZ  1 
ATOM   11251 N N   . CYS B 2 734 ? 197.134 163.720 240.077 1.00 185.27 ? 752  CYS C N   1 
ATOM   11252 C CA  . CYS B 2 734 ? 196.818 164.779 241.017 1.00 185.27 ? 752  CYS C CA  1 
ATOM   11253 C C   . CYS B 2 734 ? 195.464 164.651 241.683 1.00 185.27 ? 752  CYS C C   1 
ATOM   11254 O O   . CYS B 2 734 ? 194.448 164.656 240.994 1.00 185.27 ? 752  CYS C O   1 
ATOM   11255 C CB  . CYS B 2 734 ? 196.793 166.120 240.340 1.00 248.34 ? 752  CYS C CB  1 
ATOM   11256 S SG  . CYS B 2 734 ? 196.362 167.459 241.476 1.00 248.34 ? 752  CYS C SG  1 
ATOM   11257 N N   . PRO B 2 735 ? 195.378 164.658 243.023 1.00 188.71 ? 753  PRO C N   1 
ATOM   11258 C CA  . PRO B 2 735 ? 194.151 164.494 243.778 1.00 188.71 ? 753  PRO C CA  1 
ATOM   11259 C C   . PRO B 2 735 ? 193.269 165.732 243.819 1.00 188.71 ? 753  PRO C C   1 
ATOM   11260 O O   . PRO B 2 735 ? 192.988 166.269 244.889 1.00 188.71 ? 753  PRO C O   1 
ATOM   11261 C CB  . PRO B 2 735 ? 194.683 164.139 245.169 1.00 322.47 ? 753  PRO C CB  1 
ATOM   11262 C CG  . PRO B 2 735 ? 195.984 164.890 245.268 1.00 322.47 ? 753  PRO C CG  1 
ATOM   11263 C CD  . PRO B 2 735 ? 196.583 164.805 243.874 1.00 322.47 ? 753  PRO C CD  1 
ATOM   11264 N N   . GLU B 2 736 ? 192.841 166.173 242.648 1.00 195.76 ? 754  GLU C N   1 
ATOM   11265 C CA  . GLU B 2 736 ? 191.924 167.288 242.518 1.00 195.76 ? 754  GLU C CA  1 
ATOM   11266 C C   . GLU B 2 736 ? 190.980 167.033 241.371 1.00 195.76 ? 754  GLU C C   1 
ATOM   11267 O O   . GLU B 2 736 ? 191.394 167.035 240.218 1.00 195.76 ? 754  GLU C O   1 
ATOM   11268 C CB  . GLU B 2 736 ? 192.642 168.619 242.279 1.00 262.72 ? 754  GLU C CB  1 
ATOM   11269 C CG  . GLU B 2 736 ? 191.647 169.799 242.174 1.00 262.72 ? 754  GLU C CG  1 
ATOM   11270 C CD  . GLU B 2 736 ? 192.258 171.160 242.029 1.00 262.72 ? 754  GLU C CD  1 
ATOM   11271 O OE1 . GLU B 2 736 ? 193.451 171.288 242.102 1.00 262.72 ? 754  GLU C OE1 1 
ATOM   11272 O OE2 . GLU B 2 736 ? 191.494 172.094 241.841 1.00 262.72 ? 754  GLU C OE2 1 
ATOM   11273 N N   . ASN B 2 737 ? 189.703 166.800 241.675 1.00 197.27 ? 755  ASN C N   1 
ATOM   11274 C CA  . ASN B 2 737 ? 188.734 166.551 240.621 1.00 197.27 ? 755  ASN C CA  1 
ATOM   11275 C C   . ASN B 2 737 ? 189.292 165.609 239.575 1.00 197.27 ? 755  ASN C C   1 
ATOM   11276 O O   . ASN B 2 737 ? 189.492 166.020 238.424 1.00 197.27 ? 755  ASN C O   1 
ATOM   11277 C CB  . ASN B 2 737 ? 188.231 167.838 240.018 1.00 262.41 ? 755  ASN C CB  1 
ATOM   11278 C CG  . ASN B 2 737 ? 186.998 167.624 239.173 1.00 262.41 ? 755  ASN C CG  1 
ATOM   11279 O OD1 . ASN B 2 737 ? 186.342 166.569 239.211 1.00 262.41 ? 755  ASN C OD1 1 
ATOM   11280 N ND2 . ASN B 2 737 ? 186.641 168.630 238.442 1.00 262.41 ? 755  ASN C ND2 1 
ATOM   11281 N N   . PHE B 2 738 ? 189.509 164.344 239.953 1.00 211.71 ? 756  PHE C N   1 
ATOM   11282 C CA  . PHE B 2 738 ? 190.146 163.400 239.054 1.00 211.71 ? 756  PHE C CA  1 
ATOM   11283 C C   . PHE B 2 738 ? 189.492 163.246 237.721 1.00 211.71 ? 756  PHE C C   1 
ATOM   11284 O O   . PHE B 2 738 ? 190.164 162.927 236.747 1.00 211.71 ? 756  PHE C O   1 
ATOM   11285 C CB  . PHE B 2 738 ? 190.299 162.014 239.649 1.00 295.28 ? 756  PHE C CB  1 
ATOM   11286 C CG  . PHE B 2 738 ? 191.557 161.811 240.411 1.00 295.28 ? 756  PHE C CG  1 
ATOM   11287 C CD1 . PHE B 2 738 ? 192.768 161.859 239.727 1.00 295.28 ? 756  PHE C CD1 1 
ATOM   11288 C CD2 . PHE B 2 738 ? 191.577 161.551 241.766 1.00 295.28 ? 756  PHE C CD2 1 
ATOM   11289 C CE1 . PHE B 2 738 ? 193.940 161.655 240.362 1.00 295.28 ? 756  PHE C CE1 1 
ATOM   11290 C CE2 . PHE B 2 738 ? 192.784 161.336 242.408 1.00 295.28 ? 756  PHE C CE2 1 
ATOM   11291 C CZ  . PHE B 2 738 ? 193.967 161.391 241.696 1.00 295.28 ? 756  PHE C CZ  1 
ATOM   11292 N N   . ASN B 2 739 ? 188.200 163.480 237.597 1.00 219.11 ? 757  ASN C N   1 
ATOM   11293 C CA  . ASN B 2 739 ? 187.655 163.313 236.270 1.00 219.11 ? 757  ASN C CA  1 
ATOM   11294 C C   . ASN B 2 739 ? 188.405 164.227 235.295 1.00 219.11 ? 757  ASN C C   1 
ATOM   11295 O O   . ASN B 2 739 ? 188.681 163.850 234.154 1.00 219.11 ? 757  ASN C O   1 
ATOM   11296 C CB  . ASN B 2 739 ? 186.190 163.662 236.278 1.00 296.13 ? 757  ASN C CB  1 
ATOM   11297 C CG  . ASN B 2 739 ? 185.382 162.639 236.969 1.00 296.13 ? 757  ASN C CG  1 
ATOM   11298 O OD1 . ASN B 2 739 ? 185.797 161.485 237.121 1.00 296.13 ? 757  ASN C OD1 1 
ATOM   11299 N ND2 . ASN B 2 739 ? 184.227 163.028 237.416 1.00 296.13 ? 757  ASN C ND2 1 
ATOM   11300 N N   . GLU B 2 740 ? 188.789 165.412 235.750 1.00 212.05 ? 758  GLU C N   1 
ATOM   11301 C CA  . GLU B 2 740 ? 189.471 166.306 234.863 1.00 212.05 ? 758  GLU C CA  1 
ATOM   11302 C C   . GLU B 2 740 ? 190.944 166.038 234.924 1.00 212.05 ? 758  GLU C C   1 
ATOM   11303 O O   . GLU B 2 740 ? 191.611 166.013 233.898 1.00 212.05 ? 758  GLU C O   1 
ATOM   11304 C CB  . GLU B 2 740 ? 189.220 167.737 235.268 1.00 279.46 ? 758  GLU C CB  1 
ATOM   11305 C CG  . GLU B 2 740 ? 187.808 168.142 235.151 1.00 279.46 ? 758  GLU C CG  1 
ATOM   11306 C CD  . GLU B 2 740 ? 187.613 169.541 235.563 1.00 279.46 ? 758  GLU C CD  1 
ATOM   11307 O OE1 . GLU B 2 740 ? 188.580 170.245 235.708 1.00 279.46 ? 758  GLU C OE1 1 
ATOM   11308 O OE2 . GLU B 2 740 ? 186.484 169.930 235.766 1.00 279.46 ? 758  GLU C OE2 1 
ATOM   11309 N N   . ALA B 2 741 ? 191.478 165.761 236.114 1.00 219.43 ? 759  ALA C N   1 
ATOM   11310 C CA  . ALA B 2 741 ? 192.925 165.589 236.184 1.00 219.43 ? 759  ALA C CA  1 
ATOM   11311 C C   . ALA B 2 741 ? 193.364 164.434 235.295 1.00 219.43 ? 759  ALA C C   1 
ATOM   11312 O O   . ALA B 2 741 ? 194.363 164.545 234.566 1.00 219.43 ? 759  ALA C O   1 
ATOM   11313 C CB  . ALA B 2 741 ? 193.383 165.342 237.617 1.00 296.44 ? 759  ALA C CB  1 
ATOM   11314 N N   . LYS B 2 742 ? 192.576 163.348 235.279 1.00 217.27 ? 760  LYS C N   1 
ATOM   11315 C CA  . LYS B 2 742 ? 192.932 162.211 234.469 1.00 217.27 ? 760  LYS C CA  1 
ATOM   11316 C C   . LYS B 2 742 ? 192.897 162.585 233.019 1.00 217.27 ? 760  LYS C C   1 
ATOM   11317 O O   . LYS B 2 742 ? 193.874 162.353 232.301 1.00 217.27 ? 760  LYS C O   1 
ATOM   11318 C CB  . LYS B 2 742 ? 191.997 161.045 234.741 1.00 310.79 ? 760  LYS C CB  1 
ATOM   11319 C CG  . LYS B 2 742 ? 192.206 160.393 236.081 1.00 310.79 ? 760  LYS C CG  1 
ATOM   11320 C CD  . LYS B 2 742 ? 191.233 159.255 236.292 1.00 310.79 ? 760  LYS C CD  1 
ATOM   11321 C CE  . LYS B 2 742 ? 191.475 158.553 237.628 1.00 310.79 ? 760  LYS C CE  1 
ATOM   11322 N NZ  . LYS B 2 742 ? 190.498 157.447 237.860 1.00 310.79 ? 760  LYS C NZ  1 
ATOM   11323 N N   . PHE B 2 743 ? 191.863 163.306 232.609 1.00 226.79 ? 761  PHE C N   1 
ATOM   11324 C CA  . PHE B 2 743 ? 191.795 163.701 231.235 1.00 226.79 ? 761  PHE C CA  1 
ATOM   11325 C C   . PHE B 2 743 ? 192.835 164.711 230.849 1.00 226.79 ? 761  PHE C C   1 
ATOM   11326 O O   . PHE B 2 743 ? 193.350 164.637 229.762 1.00 226.79 ? 761  PHE C O   1 
ATOM   11327 C CB  . PHE B 2 743 ? 190.417 164.141 230.876 1.00 316.31 ? 761  PHE C CB  1 
ATOM   11328 C CG  . PHE B 2 743 ? 189.557 163.004 230.539 1.00 316.31 ? 761  PHE C CG  1 
ATOM   11329 C CD1 . PHE B 2 743 ? 188.993 162.190 231.497 1.00 316.31 ? 761  PHE C CD1 1 
ATOM   11330 C CD2 . PHE B 2 743 ? 189.283 162.759 229.218 1.00 316.31 ? 761  PHE C CD2 1 
ATOM   11331 C CE1 . PHE B 2 743 ? 188.189 161.151 231.133 1.00 316.31 ? 761  PHE C CE1 1 
ATOM   11332 C CE2 . PHE B 2 743 ? 188.479 161.727 228.846 1.00 316.31 ? 761  PHE C CE2 1 
ATOM   11333 C CZ  . PHE B 2 743 ? 187.928 160.915 229.804 1.00 316.31 ? 761  PHE C CZ  1 
ATOM   11334 N N   . ILE B 2 744 ? 193.247 165.618 231.704 1.00 229.07 ? 762  ILE C N   1 
ATOM   11335 C CA  . ILE B 2 744 ? 194.253 166.536 231.194 1.00 229.07 ? 762  ILE C CA  1 
ATOM   11336 C C   . ILE B 2 744 ? 195.484 165.708 230.836 1.00 229.07 ? 762  ILE C C   1 
ATOM   11337 O O   . ILE B 2 744 ? 196.080 165.870 229.766 1.00 229.07 ? 762  ILE C O   1 
ATOM   11338 C CB  . ILE B 2 744 ? 194.649 167.606 232.222 1.00 337.60 ? 762  ILE C CB  1 
ATOM   11339 C CG1 . ILE B 2 744 ? 193.467 168.555 232.500 1.00 337.60 ? 762  ILE C CG1 1 
ATOM   11340 C CG2 . ILE B 2 744 ? 195.804 168.426 231.635 1.00 337.60 ? 762  ILE C CG2 1 
ATOM   11341 C CD1 . ILE B 2 744 ? 193.653 169.445 233.735 1.00 337.60 ? 762  ILE C CD1 1 
ATOM   11342 N N   . GLY B 2 745 ? 195.886 164.793 231.709 1.00 236.89 ? 763  GLY C N   1 
ATOM   11343 C CA  . GLY B 2 745 ? 197.049 164.005 231.349 1.00 236.89 ? 763  GLY C CA  1 
ATOM   11344 C C   . GLY B 2 745 ? 196.808 163.195 230.060 1.00 236.89 ? 763  GLY C C   1 
ATOM   11345 O O   . GLY B 2 745 ? 197.697 163.078 229.207 1.00 236.89 ? 763  GLY C O   1 
ATOM   11346 N N   . PHE B 2 746 ? 195.584 162.690 229.874 1.00 242.94 ? 764  PHE C N   1 
ATOM   11347 C CA  . PHE B 2 746 ? 195.264 161.890 228.699 1.00 242.94 ? 764  PHE C CA  1 
ATOM   11348 C C   . PHE B 2 746 ? 195.208 162.710 227.419 1.00 242.94 ? 764  PHE C C   1 
ATOM   11349 O O   . PHE B 2 746 ? 195.720 162.279 226.370 1.00 242.94 ? 764  PHE C O   1 
ATOM   11350 C CB  . PHE B 2 746 ? 193.852 161.298 228.797 1.00 338.83 ? 764  PHE C CB  1 
ATOM   11351 C CG  . PHE B 2 746 ? 193.551 160.352 229.921 1.00 338.83 ? 764  PHE C CG  1 
ATOM   11352 C CD1 . PHE B 2 746 ? 194.536 159.697 230.639 1.00 338.83 ? 764  PHE C CD1 1 
ATOM   11353 C CD2 . PHE B 2 746 ? 192.219 160.139 230.275 1.00 338.83 ? 764  PHE C CD2 1 
ATOM   11354 C CE1 . PHE B 2 746 ? 194.200 158.850 231.672 1.00 338.83 ? 764  PHE C CE1 1 
ATOM   11355 C CE2 . PHE B 2 746 ? 191.885 159.300 231.297 1.00 338.83 ? 764  PHE C CE2 1 
ATOM   11356 C CZ  . PHE B 2 746 ? 192.874 158.650 231.996 1.00 338.83 ? 764  PHE C CZ  1 
ATOM   11357 N N   . THR B 2 747 ? 194.561 163.869 227.503 1.00 243.31 ? 765  THR C N   1 
ATOM   11358 C CA  . THR B 2 747 ? 194.266 164.680 226.361 1.00 243.31 ? 765  THR C CA  1 
ATOM   11359 C C   . THR B 2 747 ? 195.415 165.517 225.928 1.00 243.31 ? 765  THR C C   1 
ATOM   11360 O O   . THR B 2 747 ? 195.554 165.777 224.739 1.00 243.31 ? 765  THR C O   1 
ATOM   11361 C CB  . THR B 2 747 ? 193.070 165.601 226.624 1.00 340.21 ? 765  THR C CB  1 
ATOM   11362 O OG1 . THR B 2 747 ? 193.388 166.505 227.679 1.00 340.21 ? 765  THR C OG1 1 
ATOM   11363 C CG2 . THR B 2 747 ? 191.861 164.760 227.038 1.00 340.21 ? 765  THR C CG2 1 
ATOM   11364 N N   . MET B 2 748 ? 196.336 165.884 226.804 1.00 244.86 ? 766  MET C N   1 
ATOM   11365 C CA  . MET B 2 748 ? 197.437 166.644 226.257 1.00 244.86 ? 766  MET C CA  1 
ATOM   11366 C C   . MET B 2 748 ? 198.170 165.806 225.223 1.00 244.86 ? 766  MET C C   1 
ATOM   11367 O O   . MET B 2 748 ? 198.476 166.277 224.119 1.00 244.86 ? 766  MET C O   1 
ATOM   11368 C CB  . MET B 2 748 ? 198.430 167.035 227.322 1.00 340.65 ? 766  MET C CB  1 
ATOM   11369 C CG  . MET B 2 748 ? 198.028 168.083 228.262 1.00 340.65 ? 766  MET C CG  1 
ATOM   11370 S SD  . MET B 2 748 ? 199.412 168.566 229.273 1.00 340.65 ? 766  MET C SD  1 
ATOM   11371 C CE  . MET B 2 748 ? 199.615 167.169 230.369 1.00 340.65 ? 766  MET C CE  1 
ATOM   11372 N N   . TYR B 2 749 ? 198.429 164.555 225.599 1.00 257.10 ? 767  TYR C N   1 
ATOM   11373 C CA  . TYR B 2 749 ? 199.113 163.577 224.769 1.00 257.10 ? 767  TYR C CA  1 
ATOM   11374 C C   . TYR B 2 749 ? 198.292 163.207 223.549 1.00 257.10 ? 767  TYR C C   1 
ATOM   11375 O O   . TYR B 2 749 ? 198.779 163.256 222.411 1.00 257.10 ? 767  TYR C O   1 
ATOM   11376 C CB  . TYR B 2 749 ? 199.418 162.344 225.608 1.00 356.32 ? 767  TYR C CB  1 
ATOM   11377 C CG  . TYR B 2 749 ? 200.044 161.207 224.867 1.00 356.32 ? 767  TYR C CG  1 
ATOM   11378 C CD1 . TYR B 2 749 ? 201.384 161.239 224.546 1.00 356.32 ? 767  TYR C CD1 1 
ATOM   11379 C CD2 . TYR B 2 749 ? 199.274 160.112 224.527 1.00 356.32 ? 767  TYR C CD2 1 
ATOM   11380 C CE1 . TYR B 2 749 ? 201.957 160.186 223.889 1.00 356.32 ? 767  TYR C CE1 1 
ATOM   11381 C CE2 . TYR B 2 749 ? 199.846 159.056 223.872 1.00 356.32 ? 767  TYR C CE2 1 
ATOM   11382 C CZ  . TYR B 2 749 ? 201.186 159.090 223.555 1.00 356.32 ? 767  TYR C CZ  1 
ATOM   11383 O OH  . TYR B 2 749 ? 201.765 158.034 222.896 1.00 356.32 ? 767  TYR C OH  1 
ATOM   11384 N N   . THR B 2 750 ? 197.026 162.869 223.785 1.00 256.08 ? 768  THR C N   1 
ATOM   11385 C CA  . THR B 2 750 ? 196.150 162.442 222.720 1.00 256.08 ? 768  THR C CA  1 
ATOM   11386 C C   . THR B 2 750 ? 195.984 163.554 221.704 1.00 256.08 ? 768  THR C C   1 
ATOM   11387 O O   . THR B 2 750 ? 196.003 163.290 220.503 1.00 256.08 ? 768  THR C O   1 
ATOM   11388 C CB  . THR B 2 750 ? 194.775 162.016 223.274 1.00 358.07 ? 768  THR C CB  1 
ATOM   11389 O OG1 . THR B 2 750 ? 194.935 160.915 224.188 1.00 358.07 ? 768  THR C OG1 1 
ATOM   11390 C CG2 . THR B 2 750 ? 193.871 161.586 222.150 1.00 358.07 ? 768  THR C CG2 1 
ATOM   11391 N N   . THR B 2 751 ? 195.811 164.786 222.174 1.00 250.90 ? 769  THR C N   1 
ATOM   11392 C CA  . THR B 2 751 ? 195.632 165.932 221.316 1.00 250.90 ? 769  THR C CA  1 
ATOM   11393 C C   . THR B 2 751 ? 196.860 166.146 220.468 1.00 250.90 ? 769  THR C C   1 
ATOM   11394 O O   . THR B 2 751 ? 196.759 166.347 219.256 1.00 250.90 ? 769  THR C O   1 
ATOM   11395 C CB  . THR B 2 751 ? 195.334 167.191 222.127 1.00 350.83 ? 769  THR C CB  1 
ATOM   11396 O OG1 . THR B 2 751 ? 194.116 167.005 222.845 1.00 350.83 ? 769  THR C OG1 1 
ATOM   11397 C CG2 . THR B 2 751 ? 195.224 168.362 221.194 1.00 350.83 ? 769  THR C CG2 1 
ATOM   11398 N N   . CYS B 2 752 ? 198.055 166.045 221.057 1.00 260.61 ? 770  CYS C N   1 
ATOM   11399 C CA  . CYS B 2 752 ? 199.248 166.224 220.251 1.00 260.61 ? 770  CYS C CA  1 
ATOM   11400 C C   . CYS B 2 752 ? 199.180 165.279 219.063 1.00 260.61 ? 770  CYS C C   1 
ATOM   11401 O O   . CYS B 2 752 ? 199.471 165.678 217.932 1.00 260.61 ? 770  CYS C O   1 
ATOM   11402 C CB  . CYS B 2 752 ? 200.522 165.930 221.038 1.00 349.33 ? 770  CYS C CB  1 
ATOM   11403 S SG  . CYS B 2 752 ? 202.047 166.252 220.094 1.00 349.33 ? 770  CYS C SG  1 
ATOM   11404 N N   . ILE B 2 753 ? 198.821 164.025 219.326 1.00 263.92 ? 771  ILE C N   1 
ATOM   11405 C CA  . ILE B 2 753 ? 198.716 163.024 218.284 1.00 263.92 ? 771  ILE C CA  1 
ATOM   11406 C C   . ILE B 2 753 ? 197.619 163.345 217.275 1.00 263.92 ? 771  ILE C C   1 
ATOM   11407 O O   . ILE B 2 753 ? 197.847 163.201 216.073 1.00 263.92 ? 771  ILE C O   1 
ATOM   11408 C CB  . ILE B 2 753 ? 198.507 161.633 218.882 1.00 388.96 ? 771  ILE C CB  1 
ATOM   11409 C CG1 . ILE B 2 753 ? 199.789 161.242 219.632 1.00 388.96 ? 771  ILE C CG1 1 
ATOM   11410 C CG2 . ILE B 2 753 ? 198.159 160.624 217.759 1.00 388.96 ? 771  ILE C CG2 1 
ATOM   11411 C CD1 . ILE B 2 753 ? 199.660 160.056 220.522 1.00 388.96 ? 771  ILE C CD1 1 
ATOM   11412 N N   . ILE B 2 754 ? 196.440 163.761 217.736 1.00 264.54 ? 772  ILE C N   1 
ATOM   11413 C CA  . ILE B 2 754 ? 195.351 164.067 216.817 1.00 264.54 ? 772  ILE C CA  1 
ATOM   11414 C C   . ILE B 2 754 ? 195.752 165.167 215.877 1.00 264.54 ? 772  ILE C C   1 
ATOM   11415 O O   . ILE B 2 754 ? 195.540 165.080 214.668 1.00 264.54 ? 772  ILE C O   1 
ATOM   11416 C CB  . ILE B 2 754 ? 194.099 164.562 217.579 1.00 389.87 ? 772  ILE C CB  1 
ATOM   11417 C CG1 . ILE B 2 754 ? 193.491 163.435 218.408 1.00 389.87 ? 772  ILE C CG1 1 
ATOM   11418 C CG2 . ILE B 2 754 ? 193.050 165.137 216.571 1.00 389.87 ? 772  ILE C CG2 1 
ATOM   11419 C CD1 . ILE B 2 754 ? 192.485 163.913 219.448 1.00 389.87 ? 772  ILE C CD1 1 
ATOM   11420 N N   . TRP B 2 755 ? 196.310 166.221 216.427 1.00 260.44 ? 773  TRP C N   1 
ATOM   11421 C CA  . TRP B 2 755 ? 196.724 167.322 215.607 1.00 260.44 ? 773  TRP C CA  1 
ATOM   11422 C C   . TRP B 2 755 ? 197.797 166.896 214.611 1.00 260.44 ? 773  TRP C C   1 
ATOM   11423 O O   . TRP B 2 755 ? 197.696 167.214 213.417 1.00 260.44 ? 773  TRP C O   1 
ATOM   11424 C CB  . TRP B 2 755 ? 197.139 168.499 216.459 1.00 361.50 ? 773  TRP C CB  1 
ATOM   11425 C CG  . TRP B 2 755 ? 197.730 169.523 215.648 1.00 361.50 ? 773  TRP C CG  1 
ATOM   11426 C CD1 . TRP B 2 755 ? 197.117 170.479 214.916 1.00 361.50 ? 773  TRP C CD1 1 
ATOM   11427 C CD2 . TRP B 2 755 ? 199.119 169.711 215.475 1.00 361.50 ? 773  TRP C CD2 1 
ATOM   11428 N NE1 . TRP B 2 755 ? 198.048 171.237 214.278 1.00 361.50 ? 773  TRP C NE1 1 
ATOM   11429 C CE2 . TRP B 2 755 ? 199.282 170.777 214.615 1.00 361.50 ? 773  TRP C CE2 1 
ATOM   11430 C CE3 . TRP B 2 755 ? 200.226 169.068 215.978 1.00 361.50 ? 773  TRP C CE3 1 
ATOM   11431 C CZ2 . TRP B 2 755 ? 200.512 171.209 214.244 1.00 361.50 ? 773  TRP C CZ2 1 
ATOM   11432 C CZ3 . TRP B 2 755 ? 201.444 169.501 215.610 1.00 361.50 ? 773  TRP C CZ3 1 
ATOM   11433 C CH2 . TRP B 2 755 ? 201.599 170.532 214.777 1.00 361.50 ? 773  TRP C CH2 1 
ATOM   11434 N N   . LEU B 2 756 ? 198.793 166.134 215.074 1.00 262.67 ? 774  LEU C N   1 
ATOM   11435 C CA  . LEU B 2 756 ? 199.837 165.668 214.185 1.00 262.67 ? 774  LEU C CA  1 
ATOM   11436 C C   . LEU B 2 756 ? 199.264 164.805 213.088 1.00 262.67 ? 774  LEU C C   1 
ATOM   11437 O O   . LEU B 2 756 ? 199.749 164.837 211.967 1.00 262.67 ? 774  LEU C O   1 
ATOM   11438 C CB  . LEU B 2 756 ? 200.896 164.868 214.958 1.00 385.80 ? 774  LEU C CB  1 
ATOM   11439 C CG  . LEU B 2 756 ? 201.865 165.666 215.862 1.00 385.80 ? 774  LEU C CG  1 
ATOM   11440 C CD1 . LEU B 2 756 ? 202.629 164.720 216.779 1.00 385.80 ? 774  LEU C CD1 1 
ATOM   11441 C CD2 . LEU B 2 756 ? 202.868 166.398 214.960 1.00 385.80 ? 774  LEU C CD2 1 
ATOM   11442 N N   . ALA B 2 757 ? 198.230 164.029 213.381 1.00 264.52 ? 775  ALA C N   1 
ATOM   11443 C CA  . ALA B 2 757 ? 197.619 163.205 212.359 1.00 264.52 ? 775  ALA C CA  1 
ATOM   11444 C C   . ALA B 2 757 ? 197.069 164.053 211.198 1.00 264.52 ? 775  ALA C C   1 
ATOM   11445 O O   . ALA B 2 757 ? 197.141 163.637 210.038 1.00 264.52 ? 775  ALA C O   1 
ATOM   11446 C CB  . ALA B 2 757 ? 196.500 162.380 212.967 1.00 357.35 ? 775  ALA C CB  1 
ATOM   11447 N N   . PHE B 2 758 ? 196.529 165.238 211.505 1.00 266.53 ? 776  PHE C N   1 
ATOM   11448 C CA  . PHE B 2 758 ? 195.980 166.125 210.473 1.00 266.53 ? 776  PHE C CA  1 
ATOM   11449 C C   . PHE B 2 758 ? 197.049 166.889 209.698 1.00 266.53 ? 776  PHE C C   1 
ATOM   11450 O O   . PHE B 2 758 ? 196.933 167.104 208.484 1.00 266.53 ? 776  PHE C O   1 
ATOM   11451 C CB  . PHE B 2 758 ? 195.029 167.145 211.084 1.00 371.74 ? 776  PHE C CB  1 
ATOM   11452 C CG  . PHE B 2 758 ? 193.696 166.611 211.449 1.00 371.74 ? 776  PHE C CG  1 
ATOM   11453 C CD1 . PHE B 2 758 ? 192.737 166.436 210.476 1.00 371.74 ? 776  PHE C CD1 1 
ATOM   11454 C CD2 . PHE B 2 758 ? 193.379 166.300 212.746 1.00 371.74 ? 776  PHE C CD2 1 
ATOM   11455 C CE1 . PHE B 2 758 ? 191.492 165.970 210.787 1.00 371.74 ? 776  PHE C CE1 1 
ATOM   11456 C CE2 . PHE B 2 758 ? 192.123 165.824 213.065 1.00 371.74 ? 776  PHE C CE2 1 
ATOM   11457 C CZ  . PHE B 2 758 ? 191.182 165.663 212.088 1.00 371.74 ? 776  PHE C CZ  1 
ATOM   11458 N N   . LEU B 2 759 ? 198.104 167.258 210.404 1.00 263.42 ? 777  LEU C N   1 
ATOM   11459 C CA  . LEU B 2 759 ? 199.188 168.078 209.886 1.00 263.42 ? 777  LEU C CA  1 
ATOM   11460 C C   . LEU B 2 759 ? 199.747 167.805 208.466 1.00 263.42 ? 777  LEU C C   1 
ATOM   11461 O O   . LEU B 2 759 ? 199.837 168.783 207.717 1.00 263.42 ? 777  LEU C O   1 
ATOM   11462 C CB  . LEU B 2 759 ? 200.345 168.066 210.907 1.00 386.90 ? 777  LEU C CB  1 
ATOM   11463 C CG  . LEU B 2 759 ? 201.644 168.836 210.552 1.00 386.90 ? 777  LEU C CG  1 
ATOM   11464 C CD1 . LEU B 2 759 ? 201.370 170.330 210.390 1.00 386.90 ? 777  LEU C CD1 1 
ATOM   11465 C CD2 . LEU B 2 759 ? 202.650 168.591 211.665 1.00 386.90 ? 777  LEU C CD2 1 
ATOM   11466 N N   . PRO B 2 760 ? 200.027 166.548 208.006 1.00 262.67 ? 778  PRO C N   1 
ATOM   11467 C CA  . PRO B 2 760 ? 200.672 166.193 206.745 1.00 262.67 ? 778  PRO C CA  1 
ATOM   11468 C C   . PRO B 2 760 ? 199.996 166.753 205.525 1.00 262.67 ? 778  PRO C C   1 
ATOM   11469 O O   . PRO B 2 760 ? 200.629 166.871 204.473 1.00 262.67 ? 778  PRO C O   1 
ATOM   11470 C CB  . PRO B 2 760 ? 200.600 164.667 206.728 1.00 536.10 ? 778  PRO C CB  1 
ATOM   11471 C CG  . PRO B 2 760 ? 200.530 164.291 208.160 1.00 536.10 ? 778  PRO C CG  1 
ATOM   11472 C CD  . PRO B 2 760 ? 199.702 165.358 208.790 1.00 536.10 ? 778  PRO C CD  1 
ATOM   11473 N N   . ILE B 2 761 ? 198.738 167.186 205.637 1.00 258.12 ? 779  ILE C N   1 
ATOM   11474 C CA  . ILE B 2 761 ? 198.081 167.716 204.452 1.00 258.12 ? 779  ILE C CA  1 
ATOM   11475 C C   . ILE B 2 761 ? 198.872 168.897 203.884 1.00 258.12 ? 779  ILE C C   1 
ATOM   11476 O O   . ILE B 2 761 ? 198.814 169.168 202.685 1.00 258.12 ? 779  ILE C O   1 
ATOM   11477 C CB  . ILE B 2 761 ? 196.618 168.102 204.725 1.00 380.41 ? 779  ILE C CB  1 
ATOM   11478 C CG1 . ILE B 2 761 ? 196.514 169.244 205.785 1.00 380.41 ? 779  ILE C CG1 1 
ATOM   11479 C CG2 . ILE B 2 761 ? 195.881 166.839 205.172 1.00 380.41 ? 779  ILE C CG2 1 
ATOM   11480 C CD1 . ILE B 2 761 ? 195.113 169.835 205.943 1.00 380.41 ? 779  ILE C CD1 1 
ATOM   11481 N N   . PHE B 2 762 ? 199.751 169.504 204.703 1.00 255.98 ? 780  PHE C N   1 
ATOM   11482 C CA  . PHE B 2 762 ? 200.559 170.622 204.257 1.00 255.98 ? 780  PHE C CA  1 
ATOM   11483 C C   . PHE B 2 762 ? 201.402 170.302 203.030 1.00 255.98 ? 780  PHE C C   1 
ATOM   11484 O O   . PHE B 2 762 ? 201.776 171.219 202.299 1.00 255.98 ? 780  PHE C O   1 
ATOM   11485 C CB  . PHE B 2 762 ? 201.507 171.104 205.359 1.00 357.02 ? 780  PHE C CB  1 
ATOM   11486 C CG  . PHE B 2 762 ? 202.754 170.235 205.645 1.00 357.02 ? 780  PHE C CG  1 
ATOM   11487 C CD1 . PHE B 2 762 ? 203.913 170.380 204.902 1.00 357.02 ? 780  PHE C CD1 1 
ATOM   11488 C CD2 . PHE B 2 762 ? 202.788 169.350 206.699 1.00 357.02 ? 780  PHE C CD2 1 
ATOM   11489 C CE1 . PHE B 2 762 ? 205.049 169.654 205.204 1.00 357.02 ? 780  PHE C CE1 1 
ATOM   11490 C CE2 . PHE B 2 762 ? 203.906 168.621 207.006 1.00 357.02 ? 780  PHE C CE2 1 
ATOM   11491 C CZ  . PHE B 2 762 ? 205.045 168.773 206.257 1.00 357.02 ? 780  PHE C CZ  1 
ATOM   11492 N N   . TYR B 2 763 ? 201.748 169.039 202.800 1.00 257.18 ? 781  TYR C N   1 
ATOM   11493 C CA  . TYR B 2 763 ? 202.498 168.752 201.594 1.00 257.18 ? 781  TYR C CA  1 
ATOM   11494 C C   . TYR B 2 763 ? 201.710 167.746 200.801 1.00 257.18 ? 781  TYR C C   1 
ATOM   11495 O O   . TYR B 2 763 ? 201.719 167.753 199.572 1.00 257.18 ? 781  TYR C O   1 
ATOM   11496 C CB  . TYR B 2 763 ? 203.875 168.196 201.893 1.00 356.43 ? 781  TYR C CB  1 
ATOM   11497 C CG  . TYR B 2 763 ? 203.873 166.825 202.475 1.00 356.43 ? 781  TYR C CG  1 
ATOM   11498 C CD1 . TYR B 2 763 ? 203.734 166.648 203.814 1.00 356.43 ? 781  TYR C CD1 1 
ATOM   11499 C CD2 . TYR B 2 763 ? 203.985 165.729 201.644 1.00 356.43 ? 781  TYR C CD2 1 
ATOM   11500 C CE1 . TYR B 2 763 ? 203.735 165.406 204.358 1.00 356.43 ? 781  TYR C CE1 1 
ATOM   11501 C CE2 . TYR B 2 763 ? 203.987 164.467 202.178 1.00 356.43 ? 781  TYR C CE2 1 
ATOM   11502 C CZ  . TYR B 2 763 ? 203.866 164.309 203.550 1.00 356.43 ? 781  TYR C CZ  1 
ATOM   11503 O OH  . TYR B 2 763 ? 203.871 163.048 204.097 1.00 356.43 ? 781  TYR C OH  1 
ATOM   11504 N N   . VAL B 2 764 ? 200.906 166.950 201.490 1.00 257.33 ? 782  VAL C N   1 
ATOM   11505 C CA  . VAL B 2 764 ? 200.219 165.850 200.838 1.00 257.33 ? 782  VAL C CA  1 
ATOM   11506 C C   . VAL B 2 764 ? 199.264 166.332 199.779 1.00 257.33 ? 782  VAL C C   1 
ATOM   11507 O O   . VAL B 2 764 ? 199.118 165.704 198.732 1.00 257.33 ? 782  VAL C O   1 
ATOM   11508 C CB  . VAL B 2 764 ? 199.470 164.957 201.854 1.00 372.96 ? 782  VAL C CB  1 
ATOM   11509 C CG1 . VAL B 2 764 ? 198.575 163.942 201.152 1.00 372.96 ? 782  VAL C CG1 1 
ATOM   11510 C CG2 . VAL B 2 764 ? 200.473 164.226 202.711 1.00 372.96 ? 782  VAL C CG2 1 
ATOM   11511 N N   . THR B 2 765 ? 198.569 167.414 200.056 1.00 235.42 ? 783  THR C N   1 
ATOM   11512 C CA  . THR B 2 765 ? 197.562 167.903 199.155 1.00 235.42 ? 783  THR C CA  1 
ATOM   11513 C C   . THR B 2 765 ? 198.040 169.036 198.247 1.00 235.42 ? 783  THR C C   1 
ATOM   11514 O O   . THR B 2 765 ? 197.258 169.580 197.465 1.00 235.42 ? 783  THR C O   1 
ATOM   11515 C CB  . THR B 2 765 ? 196.372 168.376 199.983 1.00 329.18 ? 783  THR C CB  1 
ATOM   11516 O OG1 . THR B 2 765 ? 196.794 169.455 200.851 1.00 329.18 ? 783  THR C OG1 1 
ATOM   11517 C CG2 . THR B 2 765 ? 195.868 167.251 200.852 1.00 329.18 ? 783  THR C CG2 1 
ATOM   11518 N N   . SER B 2 766 ? 199.323 169.382 198.287 1.00 225.45 ? 784  SER C N   1 
ATOM   11519 C CA  . SER B 2 766 ? 199.786 170.551 197.548 1.00 225.45 ? 784  SER C CA  1 
ATOM   11520 C C   . SER B 2 766 ? 199.717 170.450 196.027 1.00 225.45 ? 784  SER C C   1 
ATOM   11521 O O   . SER B 2 766 ? 199.783 171.468 195.331 1.00 225.45 ? 784  SER C O   1 
ATOM   11522 C CB  . SER B 2 766 ? 201.156 170.947 198.030 1.00 302.20 ? 784  SER C CB  1 
ATOM   11523 O OG  . SER B 2 766 ? 202.141 170.018 197.721 1.00 302.20 ? 784  SER C OG  1 
ATOM   11524 N N   . SER B 2 767 ? 199.548 169.244 195.499 1.00 215.36 ? 785  SER C N   1 
ATOM   11525 C CA  . SER B 2 767 ? 199.447 169.028 194.069 1.00 215.36 ? 785  SER C CA  1 
ATOM   11526 C C   . SER B 2 767 ? 198.107 169.469 193.456 1.00 215.36 ? 785  SER C C   1 
ATOM   11527 O O   . SER B 2 767 ? 197.992 169.542 192.225 1.00 215.36 ? 785  SER C O   1 
ATOM   11528 C CB  . SER B 2 767 ? 199.649 167.565 193.750 1.00 288.68 ? 785  SER C CB  1 
ATOM   11529 O OG  . SER B 2 767 ? 198.563 166.788 194.186 1.00 288.68 ? 785  SER C OG  1 
ATOM   11530 N N   . ASP B 2 768 ? 197.074 169.704 194.276 1.00 207.92 ? 786  ASP C N   1 
ATOM   11531 C CA  . ASP B 2 768 ? 195.753 170.068 193.750 1.00 207.92 ? 786  ASP C CA  1 
ATOM   11532 C C   . ASP B 2 768 ? 195.058 171.094 194.622 1.00 207.92 ? 786  ASP C C   1 
ATOM   11533 O O   . ASP B 2 768 ? 194.677 170.807 195.757 1.00 207.92 ? 786  ASP C O   1 
ATOM   11534 C CB  . ASP B 2 768 ? 194.879 168.837 193.500 1.00 266.87 ? 786  ASP C CB  1 
ATOM   11535 C CG  . ASP B 2 768 ? 193.474 169.181 192.902 1.00 266.87 ? 786  ASP C CG  1 
ATOM   11536 O OD1 . ASP B 2 768 ? 192.947 170.269 193.198 1.00 266.87 ? 786  ASP C OD1 1 
ATOM   11537 O OD2 . ASP B 2 768 ? 192.942 168.371 192.177 1.00 266.87 ? 786  ASP C OD2 1 
ATOM   11538 N N   . TYR B 2 769 ? 194.934 172.304 194.077 1.00 198.71 ? 787  TYR C N   1 
ATOM   11539 C CA  . TYR B 2 769 ? 194.403 173.464 194.771 1.00 198.71 ? 787  TYR C CA  1 
ATOM   11540 C C   . TYR B 2 769 ? 192.944 173.339 195.199 1.00 198.71 ? 787  TYR C C   1 
ATOM   11541 O O   . TYR B 2 769 ? 192.539 173.951 196.200 1.00 198.71 ? 787  TYR C O   1 
ATOM   11542 C CB  . TYR B 2 769 ? 194.629 174.692 193.883 1.00 275.39 ? 787  TYR C CB  1 
ATOM   11543 C CG  . TYR B 2 769 ? 193.614 175.005 192.772 1.00 275.39 ? 787  TYR C CG  1 
ATOM   11544 C CD1 . TYR B 2 769 ? 193.562 174.264 191.600 1.00 275.39 ? 787  TYR C CD1 1 
ATOM   11545 C CD2 . TYR B 2 769 ? 192.731 176.052 192.948 1.00 275.39 ? 787  TYR C CD2 1 
ATOM   11546 C CE1 . TYR B 2 769 ? 192.651 174.606 190.609 1.00 275.39 ? 787  TYR C CE1 1 
ATOM   11547 C CE2 . TYR B 2 769 ? 191.857 176.395 191.951 1.00 275.39 ? 787  TYR C CE2 1 
ATOM   11548 C CZ  . TYR B 2 769 ? 191.824 175.679 190.773 1.00 275.39 ? 787  TYR C CZ  1 
ATOM   11549 O OH  . TYR B 2 769 ? 190.947 176.060 189.760 1.00 275.39 ? 787  TYR C OH  1 
ATOM   11550 N N   . ARG B 2 770 ? 192.141 172.540 194.494 1.00 187.24 ? 788  ARG C N   1 
ATOM   11551 C CA  . ARG B 2 770 ? 190.766 172.429 194.918 1.00 187.24 ? 788  ARG C CA  1 
ATOM   11552 C C   . ARG B 2 770 ? 190.723 171.421 196.022 1.00 187.24 ? 788  ARG C C   1 
ATOM   11553 O O   . ARG B 2 770 ? 189.979 171.575 197.005 1.00 187.24 ? 788  ARG C O   1 
ATOM   11554 C CB  . ARG B 2 770 ? 189.854 172.011 193.786 1.00 273.74 ? 788  ARG C CB  1 
ATOM   11555 C CG  . ARG B 2 770 ? 189.676 173.030 192.687 1.00 273.74 ? 788  ARG C CG  1 
ATOM   11556 C CD  . ARG B 2 770 ? 189.000 174.255 193.182 1.00 273.74 ? 788  ARG C CD  1 
ATOM   11557 N NE  . ARG B 2 770 ? 188.618 175.130 192.108 1.00 273.74 ? 788  ARG C NE  1 
ATOM   11558 C CZ  . ARG B 2 770 ? 188.070 176.351 192.265 1.00 273.74 ? 788  ARG C CZ  1 
ATOM   11559 N NH1 . ARG B 2 770 ? 187.761 177.068 191.199 1.00 273.74 ? 788  ARG C NH1 1 
ATOM   11560 N NH2 . ARG B 2 770 ? 187.840 176.833 193.473 1.00 273.74 ? 788  ARG C NH2 1 
ATOM   11561 N N   . VAL B 2 771 ? 191.564 170.410 195.889 1.00 196.64 ? 789  VAL C N   1 
ATOM   11562 C CA  . VAL B 2 771 ? 191.602 169.382 196.895 1.00 196.64 ? 789  VAL C CA  1 
ATOM   11563 C C   . VAL B 2 771 ? 192.160 169.898 198.192 1.00 196.64 ? 789  VAL C C   1 
ATOM   11564 O O   . VAL B 2 771 ? 191.565 169.656 199.246 1.00 196.64 ? 789  VAL C O   1 
ATOM   11565 C CB  . VAL B 2 771 ? 192.425 168.187 196.427 1.00 285.00 ? 789  VAL C CB  1 
ATOM   11566 C CG1 . VAL B 2 771 ? 192.648 167.180 197.570 1.00 285.00 ? 789  VAL C CG1 1 
ATOM   11567 C CG2 . VAL B 2 771 ? 191.678 167.520 195.296 1.00 285.00 ? 789  VAL C CG2 1 
ATOM   11568 N N   . GLN B 2 772 ? 193.278 170.617 198.165 1.00 195.62 ? 790  GLN C N   1 
ATOM   11569 C CA  . GLN B 2 772 ? 193.784 171.044 199.440 1.00 195.62 ? 790  GLN C CA  1 
ATOM   11570 C C   . GLN B 2 772 ? 192.969 172.118 200.066 1.00 195.62 ? 790  GLN C C   1 
ATOM   11571 O O   . GLN B 2 772 ? 192.948 172.209 201.291 1.00 195.62 ? 790  GLN C O   1 
ATOM   11572 C CB  . GLN B 2 772 ? 195.208 171.509 199.392 1.00 272.65 ? 790  GLN C CB  1 
ATOM   11573 C CG  . GLN B 2 772 ? 195.531 172.736 198.742 1.00 272.65 ? 790  GLN C CG  1 
ATOM   11574 C CD  . GLN B 2 772 ? 196.997 172.883 198.860 1.00 272.65 ? 790  GLN C CD  1 
ATOM   11575 O OE1 . GLN B 2 772 ? 197.613 172.073 199.592 1.00 272.65 ? 790  GLN C OE1 1 
ATOM   11576 N NE2 . GLN B 2 772 ? 197.587 173.866 198.191 1.00 272.65 ? 790  GLN C NE2 1 
ATOM   11577 N N   . THR B 2 773 ? 192.264 172.925 199.278 1.00 189.43 ? 791  THR C N   1 
ATOM   11578 C CA  . THR B 2 773 ? 191.464 173.919 199.933 1.00 189.43 ? 791  THR C CA  1 
ATOM   11579 C C   . THR B 2 773 ? 190.356 173.203 200.657 1.00 189.43 ? 791  THR C C   1 
ATOM   11580 O O   . THR B 2 773 ? 190.068 173.489 201.818 1.00 189.43 ? 791  THR C O   1 
ATOM   11581 C CB  . THR B 2 773 ? 190.849 174.936 198.967 1.00 264.87 ? 791  THR C CB  1 
ATOM   11582 O OG1 . THR B 2 773 ? 191.883 175.627 198.256 1.00 264.87 ? 791  THR C OG1 1 
ATOM   11583 C CG2 . THR B 2 773 ? 190.050 175.955 199.797 1.00 264.87 ? 791  THR C CG2 1 
ATOM   11584 N N   . THR B 2 774 ? 189.742 172.238 199.985 1.00 183.99 ? 792  THR C N   1 
ATOM   11585 C CA  . THR B 2 774 ? 188.623 171.534 200.555 1.00 183.99 ? 792  THR C CA  1 
ATOM   11586 C C   . THR B 2 774 ? 189.084 170.791 201.804 1.00 183.99 ? 792  THR C C   1 
ATOM   11587 O O   . THR B 2 774 ? 188.393 170.772 202.832 1.00 183.99 ? 792  THR C O   1 
ATOM   11588 C CB  . THR B 2 774 ? 188.039 170.549 199.506 1.00 257.27 ? 792  THR C CB  1 
ATOM   11589 O OG1 . THR B 2 774 ? 187.627 171.288 198.333 1.00 257.27 ? 792  THR C OG1 1 
ATOM   11590 C CG2 . THR B 2 774 ? 186.811 169.825 200.060 1.00 257.27 ? 792  THR C CG2 1 
ATOM   11591 N N   . THR B 2 775 ? 190.254 170.160 201.699 1.00 190.42 ? 793  THR C N   1 
ATOM   11592 C CA  . THR B 2 775 ? 190.819 169.359 202.761 1.00 190.42 ? 793  THR C CA  1 
ATOM   11593 C C   . THR B 2 775 ? 191.207 170.170 203.967 1.00 190.42 ? 793  THR C C   1 
ATOM   11594 O O   . THR B 2 775 ? 190.879 169.783 205.090 1.00 190.42 ? 793  THR C O   1 
ATOM   11595 C CB  . THR B 2 775 ? 192.075 168.610 202.277 1.00 266.26 ? 793  THR C CB  1 
ATOM   11596 O OG1 . THR B 2 775 ? 191.729 167.749 201.180 1.00 266.26 ? 793  THR C OG1 1 
ATOM   11597 C CG2 . THR B 2 775 ? 192.648 167.759 203.423 1.00 266.26 ? 793  THR C CG2 1 
ATOM   11598 N N   . MET B 2 776 ? 191.879 171.306 203.785 1.00 184.87 ? 794  MET C N   1 
ATOM   11599 C CA  . MET B 2 776 ? 192.286 172.039 204.956 1.00 184.87 ? 794  MET C CA  1 
ATOM   11600 C C   . MET B 2 776 ? 191.077 172.650 205.584 1.00 184.87 ? 794  MET C C   1 
ATOM   11601 O O   . MET B 2 776 ? 190.973 172.772 206.792 1.00 184.87 ? 794  MET C O   1 
ATOM   11602 C CB  . MET B 2 776 ? 193.285 173.128 204.596 1.00 257.20 ? 794  MET C CB  1 
ATOM   11603 C CG  . MET B 2 776 ? 192.668 174.342 203.877 1.00 257.20 ? 794  MET C CG  1 
ATOM   11604 S SD  . MET B 2 776 ? 193.861 175.483 203.215 1.00 257.20 ? 794  MET C SD  1 
ATOM   11605 C CE  . MET B 2 776 ? 194.513 176.191 204.690 1.00 257.20 ? 794  MET C CE  1 
ATOM   11606 N N   . CYS B 2 777 ? 190.081 172.979 204.789 1.00 180.16 ? 795  CYS C N   1 
ATOM   11607 C CA  . CYS B 2 777 ? 188.933 173.559 205.402 1.00 180.16 ? 795  CYS C CA  1 
ATOM   11608 C C   . CYS B 2 777 ? 188.277 172.553 206.348 1.00 180.16 ? 795  CYS C C   1 
ATOM   11609 O O   . CYS B 2 777 ? 187.950 172.882 207.500 1.00 180.16 ? 795  CYS C O   1 
ATOM   11610 C CB  . CYS B 2 777 ? 187.981 174.011 204.328 1.00 241.49 ? 795  CYS C CB  1 
ATOM   11611 S SG  . CYS B 2 777 ? 188.488 175.457 203.361 1.00 241.49 ? 795  CYS C SG  1 
ATOM   11612 N N   . VAL B 2 778 ? 188.151 171.298 205.896 1.00 182.95 ? 796  VAL C N   1 
ATOM   11613 C CA  . VAL B 2 778 ? 187.545 170.294 206.746 1.00 182.95 ? 796  VAL C CA  1 
ATOM   11614 C C   . VAL B 2 778 ? 188.423 169.944 207.915 1.00 182.95 ? 796  VAL C C   1 
ATOM   11615 O O   . VAL B 2 778 ? 187.932 169.839 209.037 1.00 182.95 ? 796  VAL C O   1 
ATOM   11616 C CB  . VAL B 2 778 ? 187.232 168.989 205.991 1.00 265.16 ? 796  VAL C CB  1 
ATOM   11617 C CG1 . VAL B 2 778 ? 186.748 167.887 206.991 1.00 265.16 ? 796  VAL C CG1 1 
ATOM   11618 C CG2 . VAL B 2 778 ? 186.169 169.242 204.969 1.00 265.16 ? 796  VAL C CG2 1 
ATOM   11619 N N   . SER B 2 779 ? 189.714 169.743 207.669 1.00 185.67 ? 797  SER C N   1 
ATOM   11620 C CA  . SER B 2 779 ? 190.618 169.345 208.722 1.00 185.67 ? 797  SER C CA  1 
ATOM   11621 C C   . SER B 2 779 ? 190.710 170.396 209.785 1.00 185.67 ? 797  SER C C   1 
ATOM   11622 O O   . SER B 2 779 ? 190.703 170.097 210.973 1.00 185.67 ? 797  SER C O   1 
ATOM   11623 C CB  . SER B 2 779 ? 191.995 169.080 208.152 1.00 248.88 ? 797  SER C CB  1 
ATOM   11624 O OG  . SER B 2 779 ? 191.988 167.947 207.323 1.00 248.88 ? 797  SER C OG  1 
ATOM   11625 N N   . VAL B 2 780 ? 190.713 171.655 209.414 1.00 186.27 ? 798  VAL C N   1 
ATOM   11626 C CA  . VAL B 2 780 ? 190.818 172.656 210.437 1.00 186.27 ? 798  VAL C CA  1 
ATOM   11627 C C   . VAL B 2 780 ? 189.572 172.636 211.330 1.00 186.27 ? 798  VAL C C   1 
ATOM   11628 O O   . VAL B 2 780 ? 189.698 172.608 212.562 1.00 186.27 ? 798  VAL C O   1 
ATOM   11629 C CB  . VAL B 2 780 ? 191.098 174.012 209.751 1.00 269.97 ? 798  VAL C CB  1 
ATOM   11630 C CG1 . VAL B 2 780 ? 191.031 175.174 210.710 1.00 269.97 ? 798  VAL C CG1 1 
ATOM   11631 C CG2 . VAL B 2 780 ? 192.514 173.953 209.144 1.00 269.97 ? 798  VAL C CG2 1 
ATOM   11632 N N   . SER B 2 781 ? 188.375 172.584 210.736 1.00 188.71 ? 799  SER C N   1 
ATOM   11633 C CA  . SER B 2 781 ? 187.166 172.550 211.555 1.00 188.71 ? 799  SER C CA  1 
ATOM   11634 C C   . SER B 2 781 ? 187.088 171.289 212.389 1.00 188.71 ? 799  SER C C   1 
ATOM   11635 O O   . SER B 2 781 ? 186.819 171.329 213.598 1.00 188.71 ? 799  SER C O   1 
ATOM   11636 C CB  . SER B 2 781 ? 185.922 172.617 210.690 1.00 252.96 ? 799  SER C CB  1 
ATOM   11637 O OG  . SER B 2 781 ? 184.751 172.597 211.491 1.00 252.96 ? 799  SER C OG  1 
ATOM   11638 N N   . LEU B 2 782 ? 187.367 170.158 211.761 1.00 191.27 ? 800  LEU C N   1 
ATOM   11639 C CA  . LEU B 2 782 ? 187.234 168.908 212.442 1.00 191.27 ? 800  LEU C CA  1 
ATOM   11640 C C   . LEU B 2 782 ? 188.249 168.744 213.526 1.00 191.27 ? 800  LEU C C   1 
ATOM   11641 O O   . LEU B 2 782 ? 187.898 168.403 214.651 1.00 191.27 ? 800  LEU C O   1 
ATOM   11642 C CB  . LEU B 2 782 ? 187.418 167.763 211.455 1.00 280.93 ? 800  LEU C CB  1 
ATOM   11643 C CG  . LEU B 2 782 ? 187.277 166.345 212.000 1.00 280.93 ? 800  LEU C CG  1 
ATOM   11644 C CD1 . LEU B 2 782 ? 185.888 166.121 212.613 1.00 280.93 ? 800  LEU C CD1 1 
ATOM   11645 C CD2 . LEU B 2 782 ? 187.495 165.392 210.851 1.00 280.93 ? 800  LEU C CD2 1 
ATOM   11646 N N   . SER B 2 783 ? 189.497 169.076 213.250 1.00 188.82 ? 801  SER C N   1 
ATOM   11647 C CA  . SER B 2 783 ? 190.532 168.866 214.223 1.00 188.82 ? 801  SER C CA  1 
ATOM   11648 C C   . SER B 2 783 ? 190.219 169.640 215.459 1.00 188.82 ? 801  SER C C   1 
ATOM   11649 O O   . SER B 2 783 ? 190.293 169.107 216.568 1.00 188.82 ? 801  SER C O   1 
ATOM   11650 C CB  . SER B 2 783 ? 191.856 169.319 213.670 1.00 253.10 ? 801  SER C CB  1 
ATOM   11651 O OG  . SER B 2 783 ? 192.883 169.104 214.590 1.00 253.10 ? 801  SER C OG  1 
ATOM   11652 N N   . GLY B 2 784 ? 189.805 170.888 215.291 1.00 189.43 ? 802  GLY C N   1 
ATOM   11653 C CA  . GLY B 2 784 ? 189.483 171.683 216.441 1.00 189.43 ? 802  GLY C CA  1 
ATOM   11654 C C   . GLY B 2 784 ? 188.358 171.035 217.247 1.00 189.43 ? 802  GLY C C   1 
ATOM   11655 O O   . GLY B 2 784 ? 188.491 170.868 218.463 1.00 189.43 ? 802  GLY C O   1 
ATOM   11656 N N   . SER B 2 785 ? 187.267 170.626 216.586 1.00 190.96 ? 803  SER C N   1 
ATOM   11657 C CA  . SER B 2 785 ? 186.139 170.043 217.305 1.00 190.96 ? 803  SER C CA  1 
ATOM   11658 C C   . SER B 2 785 ? 186.474 168.731 218.012 1.00 190.96 ? 803  SER C C   1 
ATOM   11659 O O   . SER B 2 785 ? 186.072 168.514 219.170 1.00 190.96 ? 803  SER C O   1 
ATOM   11660 C CB  . SER B 2 785 ? 185.006 169.779 216.327 1.00 255.97 ? 803  SER C CB  1 
ATOM   11661 O OG  . SER B 2 785 ? 184.454 170.968 215.823 1.00 255.97 ? 803  SER C OG  1 
ATOM   11662 N N   . VAL B 2 786 ? 187.267 167.885 217.356 1.00 185.39 ? 804  VAL C N   1 
ATOM   11663 C CA  . VAL B 2 786 ? 187.622 166.597 217.921 1.00 185.39 ? 804  VAL C CA  1 
ATOM   11664 C C   . VAL B 2 786 ? 188.413 166.813 219.177 1.00 185.39 ? 804  VAL C C   1 
ATOM   11665 O O   . VAL B 2 786 ? 188.186 166.162 220.199 1.00 185.39 ? 804  VAL C O   1 
ATOM   11666 C CB  . VAL B 2 786 ? 188.475 165.761 216.937 1.00 268.69 ? 804  VAL C CB  1 
ATOM   11667 C CG1 . VAL B 2 786 ? 189.010 164.511 217.632 1.00 268.69 ? 804  VAL C CG1 1 
ATOM   11668 C CG2 . VAL B 2 786 ? 187.639 165.342 215.741 1.00 268.69 ? 804  VAL C CG2 1 
ATOM   11669 N N   . VAL B 2 787 ? 189.345 167.733 219.103 1.00 185.39 ? 805  VAL C N   1 
ATOM   11670 C CA  . VAL B 2 787 ? 190.154 168.047 220.234 1.00 185.39 ? 805  VAL C CA  1 
ATOM   11671 C C   . VAL B 2 787 ? 189.388 168.675 221.373 1.00 185.39 ? 805  VAL C C   1 
ATOM   11672 O O   . VAL B 2 787 ? 189.579 168.287 222.521 1.00 185.39 ? 805  VAL C O   1 
ATOM   11673 C CB  . VAL B 2 787 ? 191.311 168.925 219.817 1.00 268.69 ? 805  VAL C CB  1 
ATOM   11674 C CG1 . VAL B 2 787 ? 192.040 169.442 221.068 1.00 268.69 ? 805  VAL C CG1 1 
ATOM   11675 C CG2 . VAL B 2 787 ? 192.223 168.054 218.924 1.00 268.69 ? 805  VAL C CG2 1 
ATOM   11676 N N   . LEU B 2 788 ? 188.482 169.607 221.111 1.00 187.70 ? 806  LEU C N   1 
ATOM   11677 C CA  . LEU B 2 788 ? 187.835 170.227 222.250 1.00 187.70 ? 806  LEU C CA  1 
ATOM   11678 C C   . LEU B 2 788 ? 187.116 169.197 223.093 1.00 187.70 ? 806  LEU C C   1 
ATOM   11679 O O   . LEU B 2 788 ? 187.281 169.162 224.327 1.00 187.70 ? 806  LEU C O   1 
ATOM   11680 C CB  . LEU B 2 788 ? 186.734 171.203 221.820 1.00 275.69 ? 806  LEU C CB  1 
ATOM   11681 C CG  . LEU B 2 788 ? 187.077 172.497 221.078 1.00 275.69 ? 806  LEU C CG  1 
ATOM   11682 C CD1 . LEU B 2 788 ? 185.747 173.220 220.756 1.00 275.69 ? 806  LEU C CD1 1 
ATOM   11683 C CD2 . LEU B 2 788 ? 187.964 173.345 221.873 1.00 275.69 ? 806  LEU C CD2 1 
ATOM   11684 N N   . GLY B 2 789 ? 186.473 168.254 222.413 1.00 188.45 ? 807  GLY C N   1 
ATOM   11685 C CA  . GLY B 2 789 ? 185.691 167.235 223.068 1.00 188.45 ? 807  GLY C CA  1 
ATOM   11686 C C   . GLY B 2 789 ? 186.527 166.279 223.889 1.00 188.45 ? 807  GLY C C   1 
ATOM   11687 O O   . GLY B 2 789 ? 186.006 165.568 224.755 1.00 188.45 ? 807  GLY C O   1 
ATOM   11688 N N   . CYS B 2 790 ? 187.829 166.264 223.659 1.00 185.84 ? 808  CYS C N   1 
ATOM   11689 C CA  . CYS B 2 790 ? 188.675 165.346 224.358 1.00 185.84 ? 808  CYS C CA  1 
ATOM   11690 C C   . CYS B 2 790 ? 188.666 165.650 225.842 1.00 185.84 ? 808  CYS C C   1 
ATOM   11691 O O   . CYS B 2 790 ? 188.722 164.733 226.657 1.00 185.84 ? 808  CYS C O   1 
ATOM   11692 C CB  . CYS B 2 790 ? 190.091 165.413 223.799 1.00 249.11 ? 808  CYS C CB  1 
ATOM   11693 S SG  . CYS B 2 790 ? 190.239 164.763 222.128 1.00 249.11 ? 808  CYS C SG  1 
ATOM   11694 N N   . LEU B 2 791 ? 188.620 166.937 226.211 1.00 180.84 ? 809  LEU C N   1 
ATOM   11695 C CA  . LEU B 2 791 ? 188.623 167.293 227.626 1.00 180.84 ? 809  LEU C CA  1 
ATOM   11696 C C   . LEU B 2 791 ? 187.246 167.722 228.057 1.00 180.84 ? 809  LEU C C   1 
ATOM   11697 O O   . LEU B 2 791 ? 186.921 167.704 229.249 1.00 180.84 ? 809  LEU C O   1 
ATOM   11698 C CB  . LEU B 2 791 ? 189.680 168.345 227.973 1.00 265.61 ? 809  LEU C CB  1 
ATOM   11699 C CG  . LEU B 2 791 ? 189.806 168.750 229.521 1.00 265.61 ? 809  LEU C CG  1 
ATOM   11700 C CD1 . LEU B 2 791 ? 190.111 167.523 230.402 1.00 265.61 ? 809  LEU C CD1 1 
ATOM   11701 C CD2 . LEU B 2 791 ? 190.954 169.737 229.674 1.00 265.61 ? 809  LEU C CD2 1 
ATOM   11702 N N   . PHE B 2 792 ? 186.425 168.149 227.107 1.00 183.99 ? 810  PHE C N   1 
ATOM   11703 C CA  . PHE B 2 792 ? 185.120 168.562 227.518 1.00 183.99 ? 810  PHE C CA  1 
ATOM   11704 C C   . PHE B 2 792 ? 184.376 167.351 228.008 1.00 183.99 ? 810  PHE C C   1 
ATOM   11705 O O   . PHE B 2 792 ? 183.506 167.486 228.849 1.00 183.99 ? 810  PHE C O   1 
ATOM   11706 C CB  . PHE B 2 792 ? 184.313 169.196 226.412 1.00 256.62 ? 810  PHE C CB  1 
ATOM   11707 C CG  . PHE B 2 792 ? 184.731 170.536 225.963 1.00 256.62 ? 810  PHE C CG  1 
ATOM   11708 C CD1 . PHE B 2 792 ? 185.692 171.296 226.622 1.00 256.62 ? 810  PHE C CD1 1 
ATOM   11709 C CD2 . PHE B 2 792 ? 184.115 171.079 224.869 1.00 256.62 ? 810  PHE C CD2 1 
ATOM   11710 C CE1 . PHE B 2 792 ? 186.014 172.543 226.167 1.00 256.62 ? 810  PHE C CE1 1 
ATOM   11711 C CE2 . PHE B 2 792 ? 184.434 172.332 224.430 1.00 256.62 ? 810  PHE C CE2 1 
ATOM   11712 C CZ  . PHE B 2 792 ? 185.389 173.058 225.077 1.00 256.62 ? 810  PHE C CZ  1 
ATOM   11713 N N   . ALA B 2 793 ? 184.702 166.151 227.516 1.00 177.15 ? 811  ALA C N   1 
ATOM   11714 C CA  . ALA B 2 793 ? 184.008 164.964 227.976 1.00 177.15 ? 811  ALA C CA  1 
ATOM   11715 C C   . ALA B 2 793 ? 183.784 164.975 229.520 1.00 177.15 ? 811  ALA C C   1 
ATOM   11716 O O   . ALA B 2 793 ? 182.617 164.915 229.921 1.00 177.15 ? 811  ALA C O   1 
ATOM   11717 C CB  . ALA B 2 793 ? 184.759 163.715 227.481 1.00 239.32 ? 811  ALA C CB  1 
ATOM   11718 N N   . PRO B 2 794 ? 184.801 165.011 230.429 1.00 177.49 ? 812  PRO C N   1 
ATOM   11719 C CA  . PRO B 2 794 ? 184.569 165.106 231.859 1.00 177.49 ? 812  PRO C CA  1 
ATOM   11720 C C   . PRO B 2 794 ? 183.993 166.439 232.303 1.00 177.49 ? 812  PRO C C   1 
ATOM   11721 O O   . PRO B 2 794 ? 183.278 166.491 233.306 1.00 177.49 ? 812  PRO C O   1 
ATOM   11722 C CB  . PRO B 2 794 ? 185.966 164.934 232.445 1.00 362.26 ? 812  PRO C CB  1 
ATOM   11723 C CG  . PRO B 2 794 ? 186.875 165.321 231.349 1.00 362.26 ? 812  PRO C CG  1 
ATOM   11724 C CD  . PRO B 2 794 ? 186.199 164.824 230.092 1.00 362.26 ? 812  PRO C CD  1 
ATOM   11725 N N   . LYS B 2 795 ? 184.208 167.517 231.537 1.00 171.05 ? 813  LYS C N   1 
ATOM   11726 C CA  . LYS B 2 795 ? 183.658 168.775 232.018 1.00 171.05 ? 813  LYS C CA  1 
ATOM   11727 C C   . LYS B 2 795 ? 182.154 168.776 231.894 1.00 171.05 ? 813  LYS C C   1 
ATOM   11728 O O   . LYS B 2 795 ? 181.438 169.220 232.796 1.00 171.05 ? 813  LYS C O   1 
ATOM   11729 C CB  . LYS B 2 795 ? 184.146 169.960 231.193 1.00 254.35 ? 813  LYS C CB  1 
ATOM   11730 C CG  . LYS B 2 795 ? 185.653 170.291 231.208 1.00 254.35 ? 813  LYS C CG  1 
ATOM   11731 C CD  . LYS B 2 795 ? 186.188 170.633 232.585 1.00 254.35 ? 813  LYS C CD  1 
ATOM   11732 C CE  . LYS B 2 795 ? 185.637 171.958 233.160 1.00 254.35 ? 813  LYS C CE  1 
ATOM   11733 N NZ  . LYS B 2 795 ? 186.289 172.304 234.463 1.00 254.35 ? 813  LYS C NZ  1 
ATOM   11734 N N   . LEU B 2 796 ? 181.693 168.251 230.772 1.00 165.02 ? 814  LEU C N   1 
ATOM   11735 C CA  . LEU B 2 796 ? 180.296 168.200 230.440 1.00 165.02 ? 814  LEU C CA  1 
ATOM   11736 C C   . LEU B 2 796 ? 179.667 167.044 231.155 1.00 165.02 ? 814  LEU C C   1 
ATOM   11737 O O   . LEU B 2 796 ? 178.512 167.114 231.556 1.00 165.02 ? 814  LEU C O   1 
ATOM   11738 C CB  . LEU B 2 796 ? 180.123 168.124 228.922 1.00 242.38 ? 814  LEU C CB  1 
ATOM   11739 C CG  . LEU B 2 796 ? 180.604 169.390 228.134 1.00 242.38 ? 814  LEU C CG  1 
ATOM   11740 C CD1 . LEU B 2 796 ? 180.510 169.115 226.644 1.00 242.38 ? 814  LEU C CD1 1 
ATOM   11741 C CD2 . LEU B 2 796 ? 179.745 170.628 228.498 1.00 242.38 ? 814  LEU C CD2 1 
ATOM   11742 N N   . HIS B 2 797 ? 180.423 165.985 231.428 1.00 167.37 ? 815  HIS C N   1 
ATOM   11743 C CA  . HIS B 2 797 ? 179.811 164.944 232.208 1.00 167.37 ? 815  HIS C CA  1 
ATOM   11744 C C   . HIS B 2 797 ? 179.329 165.532 233.520 1.00 167.37 ? 815  HIS C C   1 
ATOM   11745 O O   . HIS B 2 797 ? 178.175 165.364 233.911 1.00 167.37 ? 815  HIS C O   1 
ATOM   11746 C CB  . HIS B 2 797 ? 180.789 163.794 232.457 1.00 30.00  ? 815  HIS C CB  1 
ATOM   11747 C CG  . HIS B 2 797 ? 181.268 163.127 231.206 1.00 30.00  ? 815  HIS C CG  1 
ATOM   11748 N ND1 . HIS B 2 797 ? 180.446 162.361 230.407 1.00 30.00  ? 815  HIS C ND1 1 
ATOM   11749 C CD2 . HIS B 2 797 ? 182.486 163.112 230.615 1.00 30.00  ? 815  HIS C CD2 1 
ATOM   11750 C CE1 . HIS B 2 797 ? 181.137 161.902 229.379 1.00 30.00  ? 815  HIS C CE1 1 
ATOM   11751 N NE2 . HIS B 2 797 ? 182.377 162.342 229.480 1.00 30.00  ? 815  HIS C NE2 1 
ATOM   11752 N N   . ILE B 2 798 ? 180.195 166.269 234.200 1.00 168.65 ? 816  ILE C N   1 
ATOM   11753 C CA  . ILE B 2 798 ? 179.783 166.808 235.474 1.00 168.65 ? 816  ILE C CA  1 
ATOM   11754 C C   . ILE B 2 798 ? 178.665 167.839 235.302 1.00 168.65 ? 816  ILE C C   1 
ATOM   11755 O O   . ILE B 2 798 ? 177.622 167.762 235.960 1.00 168.65 ? 816  ILE C O   1 
ATOM   11756 C CB  . ILE B 2 798 ? 180.981 167.471 236.184 1.00 248.55 ? 816  ILE C CB  1 
ATOM   11757 C CG1 . ILE B 2 798 ? 182.027 166.377 236.557 1.00 248.55 ? 816  ILE C CG1 1 
ATOM   11758 C CG2 . ILE B 2 798 ? 180.487 168.231 237.452 1.00 248.55 ? 816  ILE C CG2 1 
ATOM   11759 C CD1 . ILE B 2 798 ? 183.396 166.916 236.984 1.00 248.55 ? 816  ILE C CD1 1 
ATOM   11760 N N   . ILE B 2 799 ? 178.825 168.772 234.366 1.00 170.18 ? 817  ILE C N   1 
ATOM   11761 C CA  . ILE B 2 799 ? 177.827 169.819 234.217 1.00 170.18 ? 817  ILE C CA  1 
ATOM   11762 C C   . ILE B 2 799 ? 176.457 169.338 233.763 1.00 170.18 ? 817  ILE C C   1 
ATOM   11763 O O   . ILE B 2 799 ? 175.433 169.789 234.284 1.00 170.18 ? 817  ILE C O   1 
ATOM   11764 C CB  . ILE B 2 799 ? 178.279 170.875 233.193 1.00 250.81 ? 817  ILE C CB  1 
ATOM   11765 C CG1 . ILE B 2 799 ? 179.482 171.617 233.711 1.00 250.81 ? 817  ILE C CG1 1 
ATOM   11766 C CG2 . ILE B 2 799 ? 177.135 171.866 232.989 1.00 250.81 ? 817  ILE C CG2 1 
ATOM   11767 C CD1 . ILE B 2 799 ? 180.219 172.476 232.641 1.00 250.81 ? 817  ILE C CD1 1 
ATOM   11768 N N   . LEU B 2 800 ? 176.426 168.473 232.761 1.00 170.19 ? 818  LEU C N   1 
ATOM   11769 C CA  . LEU B 2 800 ? 175.178 168.049 232.175 1.00 170.19 ? 818  LEU C CA  1 
ATOM   11770 C C   . LEU B 2 800 ? 174.539 166.852 232.867 1.00 170.19 ? 818  LEU C C   1 
ATOM   11771 O O   . LEU B 2 800 ? 173.315 166.716 232.834 1.00 170.19 ? 818  LEU C O   1 
ATOM   11772 C CB  . LEU B 2 800 ? 175.422 167.686 230.702 1.00 249.97 ? 818  LEU C CB  1 
ATOM   11773 C CG  . LEU B 2 800 ? 176.000 168.805 229.768 1.00 249.97 ? 818  LEU C CG  1 
ATOM   11774 C CD1 . LEU B 2 800 ? 176.227 168.200 228.389 1.00 249.97 ? 818  LEU C CD1 1 
ATOM   11775 C CD2 . LEU B 2 800 ? 175.071 170.013 229.690 1.00 249.97 ? 818  LEU C CD2 1 
ATOM   11776 N N   . PHE B 2 801 ? 175.329 165.973 233.494 1.00 174.72 ? 819  PHE C N   1 
ATOM   11777 C CA  . PHE B 2 801 ? 174.740 164.777 234.096 1.00 174.72 ? 819  PHE C CA  1 
ATOM   11778 C C   . PHE B 2 801 ? 174.664 164.743 235.642 1.00 174.72 ? 819  PHE C C   1 
ATOM   11779 O O   . PHE B 2 801 ? 173.943 163.890 236.171 1.00 174.72 ? 819  PHE C O   1 
ATOM   11780 C CB  . PHE B 2 801 ? 175.491 163.550 233.580 1.00 243.69 ? 819  PHE C CB  1 
ATOM   11781 C CG  . PHE B 2 801 ? 175.365 163.379 232.089 1.00 243.69 ? 819  PHE C CG  1 
ATOM   11782 C CD1 . PHE B 2 801 ? 176.205 164.062 231.249 1.00 243.69 ? 819  PHE C CD1 1 
ATOM   11783 C CD2 . PHE B 2 801 ? 174.434 162.531 231.531 1.00 243.69 ? 819  PHE C CD2 1 
ATOM   11784 C CE1 . PHE B 2 801 ? 176.135 163.933 229.890 1.00 243.69 ? 819  PHE C CE1 1 
ATOM   11785 C CE2 . PHE B 2 801 ? 174.353 162.387 230.158 1.00 243.69 ? 819  PHE C CE2 1 
ATOM   11786 C CZ  . PHE B 2 801 ? 175.209 163.095 229.338 1.00 243.69 ? 819  PHE C CZ  1 
ATOM   11787 N N   . GLN B 2 802 ? 175.369 165.662 236.377 1.00 178.66 ? 820  GLN C N   1 
ATOM   11788 C CA  . GLN B 2 802 ? 175.387 165.711 237.846 1.00 178.66 ? 820  GLN C CA  1 
ATOM   11789 C C   . GLN B 2 802 ? 174.765 167.042 238.269 1.00 178.66 ? 820  GLN C C   1 
ATOM   11790 O O   . GLN B 2 802 ? 173.983 167.114 239.225 1.00 178.66 ? 820  GLN C O   1 
ATOM   11791 C CB  . GLN B 2 802 ? 176.837 165.565 238.425 1.00 249.01 ? 820  GLN C CB  1 
ATOM   11792 C CG  . GLN B 2 802 ? 177.584 164.187 238.108 1.00 249.01 ? 820  GLN C CG  1 
ATOM   11793 C CD  . GLN B 2 802 ? 179.023 164.059 238.807 1.00 249.01 ? 820  GLN C CD  1 
ATOM   11794 O OE1 . GLN B 2 802 ? 179.757 165.055 238.966 1.00 249.01 ? 820  GLN C OE1 1 
ATOM   11795 N NE2 . GLN B 2 802 ? 179.398 162.787 239.248 1.00 249.01 ? 820  GLN C NE2 1 
HETATM 11796 O O1  . E7P C 3 .   ? 199.451 220.145 110.804 1.00 20.00  ? 1001 E7P B O1  1 
HETATM 11797 O O2  . E7P C 3 .   ? 200.275 222.352 110.400 1.00 20.00  ? 1001 E7P B O2  1 
HETATM 11798 C C1  . E7P C 3 .   ? 200.291 221.442 113.020 1.00 20.00  ? 1001 E7P B C1  1 
HETATM 11799 C C   . E7P C 3 .   ? 198.626 219.447 114.947 1.00 20.00  ? 1001 E7P B C   1 
HETATM 11800 C CA  . E7P C 3 .   ? 198.430 219.867 113.510 1.00 20.00  ? 1001 E7P B CA  1 
HETATM 11801 C C2  . E7P C 3 .   ? 198.819 221.326 113.359 1.00 20.00  ? 1001 E7P B C2  1 
HETATM 11802 O O   . E7P C 3 .   ? 199.778 219.355 115.423 1.00 20.00  ? 1001 E7P B O   1 
HETATM 11803 O OXT . E7P C 3 .   ? 197.625 219.192 115.650 1.00 20.00  ? 1001 E7P B OXT 1 
HETATM 11804 N N   . E7P C 3 .   ? 197.033 219.734 113.189 1.00 20.00  ? 1001 E7P B N   1 
HETATM 11805 P P   . E7P C 3 .   ? 200.484 221.130 111.215 1.00 20.00  ? 1001 E7P B P   1 
HETATM 11806 O O3  . E7P C 3 .   ? 201.865 220.622 110.936 1.00 20.00  ? 1001 E7P B O3  1 
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