data_8W8W
# 
_entry.id   8W8W 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8W8W         pdb_00008w8w 10.2210/pdb8w8w/pdb 
WWPDB D_1300038484 ?            ?                   
EMDB  EMD-37359    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-03-19 ? 
2 'EM metadata'     1 0 2025-03-19 ? 
3 FSC               1 0 2025-03-19 ? 
4 'Half map'        1 0 2025-03-19 1 
5 'Half map'        1 0 2025-03-19 2 
6 Image             1 0 2025-03-19 ? 
7 'Primary map'     1 0 2025-03-19 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 FSC               repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 'Half map'        repository 'Initial release' ? ? 
6 6 Image             repository 'Initial release' ? ? 
7 7 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8W8W 
_pdbx_database_status.recvd_initial_deposition_date   2023-09-04 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBC 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure of alpha-MSH-MC3R-Gs_Nb35 complex' 
_pdbx_database_related.db_id          EMD-37359 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              honglihu@cuhk.edu.cn 
_pdbx_contact_author.name_first         Hongli 
_pdbx_contact_author.name_last          Hu 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-3658-272X 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Chen, Q.' 1 ? 
'Fu, J.'   2 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Structure basis of ligand selectivity and signal transduction  in human melanocortin-3 receptor' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Jingpeng, F.' 1 ? 
primary 'Hongli, H.'   2 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Soluble cytochrome b562,Melanocortin receptor 3,Fusion protein'       67048.805 1 ? ? ? ? 
2 polymer     man 'Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1'     41729.582 1 ? ? ? ? 
3 polymer     man 'Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2'    7861.143  1 ? ? ? ? 
4 polymer     man Nanobody35                                                             17352.498 1 ? ? ? ? 
5 polymer     syn alpha-MSH                                                              1626.856  1 ? ? ? ? 
6 polymer     man 'Guanine nucleotide-binding protein G(s) subunit alpha isoforms short' 44326.160 1 ? ? ? ? 
7 non-polymer syn 'CALCIUM ION'                                                          40.078    1 ? ? ? ? 
# 
loop_
_entity_name_com.entity_id 
_entity_name_com.name 
1 'Cytochrome b-562,MC3-R'                        
2 'Transducin beta chain 1'                       
3 'G gamma-I'                                     
6 'Adenylate cyclase-stimulating G alpha protein' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;DYKDDDDKGSADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVG
QIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLLVPRGSNASCCLPSVQPTLPNGSEHLQAPFFSNQSSSAFCEQVF
IKPEVFLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNI
FDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFIVYSESKMVIVCLITMFFAM
MLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTA
HFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILCGCNGMNLGVFTLEDFVGDWEQTAAYNLDQVLEQGGVSSLLQNLA
VSVTPIQRIVRSGENALKIDIHVIIPYEGLSADQMAQIEEVFKVVYPVDDHHFKVILPYGTLVIDGVTPNMLNYFGRPYE
GIAVFDGKKITVTGTLWNGNKIIDERLITPDGSMLFRVTINS
;
;DYKDDDDKGSADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVG
QIDDALKLANEGKVKEAQAAAEQLKTTRNAYIQKYLLVPRGSNASCCLPSVQPTLPNGSEHLQAPFFSNQSSSAFCEQVF
IKPEVFLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNI
FDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFIVYSESKMVIVCLITMFFAM
MLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTA
HFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILCGCNGMNLGVFTLEDFVGDWEQTAAYNLDQVLEQGGVSSLLQNLA
VSVTPIQRIVRSGENALKIDIHVIIPYEGLSADQMAQIEEVFKVVYPVDDHHFKVILPYGTLVIDGVTPNMLNYFGRPYE
GIAVFDGKKITVTGTLWNGNKIIDERLITPDGSMLFRVTINS
;
R ? 
2 'polypeptide(L)' no no 
;MHHHHHHLEVLFQGPGSSGSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMH
WGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGH
TGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTF
TGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKA
DRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWNGSSGGGGSGGGGSSGVSGWRLFKKIS
;
;MHHHHHHLEVLFQGPGSSGSELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMH
WGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGH
TGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTF
TGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKA
DRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWNGSSGGGGSGGGGSSGVSGWRLFKKIS
;
B ? 
3 'polypeptide(L)' no no MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL 
MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL G ? 
4 'polypeptide(L)' no no 
;MKYLLPTAAAGLLLLAAQPAMAQVQLQESGGGLVQPGGSLRLSCAASGFTFSNYKMNWVRQAPGKGLEWVSDISQSGASI
SYTGSVKGRFTISRDNAKNTLYLQMNSLKPEDTAVYYCARCPAPFTRDCFDVTSTTYAYRGQGTQVTVSSHHHHHHEPEA
;
;MKYLLPTAAAGLLLLAAQPAMAQVQLQESGGGLVQPGGSLRLSCAASGFTFSNYKMNWVRQAPGKGLEWVSDISQSGASI
SYTGSVKGRFTISRDNAKNTLYLQMNSLKPEDTAVYYCARCPAPFTRDCFDVTSTTYAYRGQGTQVTVSSHHHHHHEPEA
;
N ? 
5 'polypeptide(L)' no no SYSMEHFRWGKPV SYSMEHFRWGKPV L ? 
6 'polypeptide(L)' no no 
;MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGDSEKATKVQD
IKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDC
AQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYN
MVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRV
TRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL
;
;MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGDSEKATKVQD
IKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDC
AQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYN
MVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRV
TRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL
;
A ? 
# 
_pdbx_entity_nonpoly.entity_id   7 
_pdbx_entity_nonpoly.name        'CALCIUM ION' 
_pdbx_entity_nonpoly.comp_id     CA 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   ASP n 
1 2   TYR n 
1 3   LYS n 
1 4   ASP n 
1 5   ASP n 
1 6   ASP n 
1 7   ASP n 
1 8   LYS n 
1 9   GLY n 
1 10  SER n 
1 11  ALA n 
1 12  ASP n 
1 13  LEU n 
1 14  GLU n 
1 15  ASP n 
1 16  ASN n 
1 17  TRP n 
1 18  GLU n 
1 19  THR n 
1 20  LEU n 
1 21  ASN n 
1 22  ASP n 
1 23  ASN n 
1 24  LEU n 
1 25  LYS n 
1 26  VAL n 
1 27  ILE n 
1 28  GLU n 
1 29  LYS n 
1 30  ALA n 
1 31  ASP n 
1 32  ASN n 
1 33  ALA n 
1 34  ALA n 
1 35  GLN n 
1 36  VAL n 
1 37  LYS n 
1 38  ASP n 
1 39  ALA n 
1 40  LEU n 
1 41  THR n 
1 42  LYS n 
1 43  MET n 
1 44  ARG n 
1 45  ALA n 
1 46  ALA n 
1 47  ALA n 
1 48  LEU n 
1 49  ASP n 
1 50  ALA n 
1 51  GLN n 
1 52  LYS n 
1 53  ALA n 
1 54  THR n 
1 55  PRO n 
1 56  PRO n 
1 57  LYS n 
1 58  LEU n 
1 59  GLU n 
1 60  ASP n 
1 61  LYS n 
1 62  SER n 
1 63  PRO n 
1 64  ASP n 
1 65  SER n 
1 66  PRO n 
1 67  GLU n 
1 68  MET n 
1 69  LYS n 
1 70  ASP n 
1 71  PHE n 
1 72  ARG n 
1 73  HIS n 
1 74  GLY n 
1 75  PHE n 
1 76  ASP n 
1 77  ILE n 
1 78  LEU n 
1 79  VAL n 
1 80  GLY n 
1 81  GLN n 
1 82  ILE n 
1 83  ASP n 
1 84  ASP n 
1 85  ALA n 
1 86  LEU n 
1 87  LYS n 
1 88  LEU n 
1 89  ALA n 
1 90  ASN n 
1 91  GLU n 
1 92  GLY n 
1 93  LYS n 
1 94  VAL n 
1 95  LYS n 
1 96  GLU n 
1 97  ALA n 
1 98  GLN n 
1 99  ALA n 
1 100 ALA n 
1 101 ALA n 
1 102 GLU n 
1 103 GLN n 
1 104 LEU n 
1 105 LYS n 
1 106 THR n 
1 107 THR n 
1 108 ARG n 
1 109 ASN n 
1 110 ALA n 
1 111 TYR n 
1 112 ILE n 
1 113 GLN n 
1 114 LYS n 
1 115 TYR n 
1 116 LEU n 
1 117 LEU n 
1 118 VAL n 
1 119 PRO n 
1 120 ARG n 
1 121 GLY n 
1 122 SER n 
1 123 ASN n 
1 124 ALA n 
1 125 SER n 
1 126 CYS n 
1 127 CYS n 
1 128 LEU n 
1 129 PRO n 
1 130 SER n 
1 131 VAL n 
1 132 GLN n 
1 133 PRO n 
1 134 THR n 
1 135 LEU n 
1 136 PRO n 
1 137 ASN n 
1 138 GLY n 
1 139 SER n 
1 140 GLU n 
1 141 HIS n 
1 142 LEU n 
1 143 GLN n 
1 144 ALA n 
1 145 PRO n 
1 146 PHE n 
1 147 PHE n 
1 148 SER n 
1 149 ASN n 
1 150 GLN n 
1 151 SER n 
1 152 SER n 
1 153 SER n 
1 154 ALA n 
1 155 PHE n 
1 156 CYS n 
1 157 GLU n 
1 158 GLN n 
1 159 VAL n 
1 160 PHE n 
1 161 ILE n 
1 162 LYS n 
1 163 PRO n 
1 164 GLU n 
1 165 VAL n 
1 166 PHE n 
1 167 LEU n 
1 168 SER n 
1 169 LEU n 
1 170 GLY n 
1 171 ILE n 
1 172 VAL n 
1 173 SER n 
1 174 LEU n 
1 175 LEU n 
1 176 GLU n 
1 177 ASN n 
1 178 ILE n 
1 179 LEU n 
1 180 VAL n 
1 181 ILE n 
1 182 LEU n 
1 183 ALA n 
1 184 VAL n 
1 185 VAL n 
1 186 ARG n 
1 187 ASN n 
1 188 GLY n 
1 189 ASN n 
1 190 LEU n 
1 191 HIS n 
1 192 SER n 
1 193 PRO n 
1 194 MET n 
1 195 TYR n 
1 196 PHE n 
1 197 PHE n 
1 198 LEU n 
1 199 CYS n 
1 200 SER n 
1 201 LEU n 
1 202 ALA n 
1 203 VAL n 
1 204 ALA n 
1 205 ASP n 
1 206 MET n 
1 207 LEU n 
1 208 VAL n 
1 209 SER n 
1 210 VAL n 
1 211 SER n 
1 212 ASN n 
1 213 ALA n 
1 214 LEU n 
1 215 GLU n 
1 216 THR n 
1 217 ILE n 
1 218 MET n 
1 219 ILE n 
1 220 ALA n 
1 221 ILE n 
1 222 VAL n 
1 223 HIS n 
1 224 SER n 
1 225 ASP n 
1 226 TYR n 
1 227 LEU n 
1 228 THR n 
1 229 PHE n 
1 230 GLU n 
1 231 ASP n 
1 232 GLN n 
1 233 PHE n 
1 234 ILE n 
1 235 GLN n 
1 236 HIS n 
1 237 MET n 
1 238 ASP n 
1 239 ASN n 
1 240 ILE n 
1 241 PHE n 
1 242 ASP n 
1 243 SER n 
1 244 MET n 
1 245 ILE n 
1 246 CYS n 
1 247 ILE n 
1 248 SER n 
1 249 LEU n 
1 250 VAL n 
1 251 ALA n 
1 252 SER n 
1 253 ILE n 
1 254 CYS n 
1 255 ASN n 
1 256 LEU n 
1 257 LEU n 
1 258 ALA n 
1 259 ILE n 
1 260 ALA n 
1 261 VAL n 
1 262 ASP n 
1 263 ARG n 
1 264 TYR n 
1 265 VAL n 
1 266 THR n 
1 267 ILE n 
1 268 PHE n 
1 269 TYR n 
1 270 ALA n 
1 271 LEU n 
1 272 ARG n 
1 273 TYR n 
1 274 HIS n 
1 275 SER n 
1 276 ILE n 
1 277 MET n 
1 278 THR n 
1 279 VAL n 
1 280 ARG n 
1 281 LYS n 
1 282 ALA n 
1 283 LEU n 
1 284 THR n 
1 285 LEU n 
1 286 ILE n 
1 287 VAL n 
1 288 ALA n 
1 289 ILE n 
1 290 TRP n 
1 291 VAL n 
1 292 CYS n 
1 293 CYS n 
1 294 GLY n 
1 295 VAL n 
1 296 CYS n 
1 297 GLY n 
1 298 VAL n 
1 299 VAL n 
1 300 PHE n 
1 301 ILE n 
1 302 VAL n 
1 303 TYR n 
1 304 SER n 
1 305 GLU n 
1 306 SER n 
1 307 LYS n 
1 308 MET n 
1 309 VAL n 
1 310 ILE n 
1 311 VAL n 
1 312 CYS n 
1 313 LEU n 
1 314 ILE n 
1 315 THR n 
1 316 MET n 
1 317 PHE n 
1 318 PHE n 
1 319 ALA n 
1 320 MET n 
1 321 MET n 
1 322 LEU n 
1 323 LEU n 
1 324 MET n 
1 325 GLY n 
1 326 THR n 
1 327 LEU n 
1 328 TYR n 
1 329 VAL n 
1 330 HIS n 
1 331 MET n 
1 332 PHE n 
1 333 LEU n 
1 334 PHE n 
1 335 ALA n 
1 336 ARG n 
1 337 LEU n 
1 338 HIS n 
1 339 VAL n 
1 340 LYS n 
1 341 ARG n 
1 342 ILE n 
1 343 ALA n 
1 344 ALA n 
1 345 LEU n 
1 346 PRO n 
1 347 PRO n 
1 348 ALA n 
1 349 ASP n 
1 350 GLY n 
1 351 VAL n 
1 352 ALA n 
1 353 PRO n 
1 354 GLN n 
1 355 GLN n 
1 356 HIS n 
1 357 SER n 
1 358 CYS n 
1 359 MET n 
1 360 LYS n 
1 361 GLY n 
1 362 ALA n 
1 363 VAL n 
1 364 THR n 
1 365 ILE n 
1 366 THR n 
1 367 ILE n 
1 368 LEU n 
1 369 LEU n 
1 370 GLY n 
1 371 VAL n 
1 372 PHE n 
1 373 ILE n 
1 374 PHE n 
1 375 CYS n 
1 376 TRP n 
1 377 ALA n 
1 378 PRO n 
1 379 PHE n 
1 380 PHE n 
1 381 LEU n 
1 382 HIS n 
1 383 LEU n 
1 384 VAL n 
1 385 LEU n 
1 386 ILE n 
1 387 ILE n 
1 388 THR n 
1 389 CYS n 
1 390 PRO n 
1 391 THR n 
1 392 ASN n 
1 393 PRO n 
1 394 TYR n 
1 395 CYS n 
1 396 ILE n 
1 397 CYS n 
1 398 TYR n 
1 399 THR n 
1 400 ALA n 
1 401 HIS n 
1 402 PHE n 
1 403 ASN n 
1 404 THR n 
1 405 TYR n 
1 406 LEU n 
1 407 VAL n 
1 408 LEU n 
1 409 ILE n 
1 410 MET n 
1 411 CYS n 
1 412 ASN n 
1 413 SER n 
1 414 VAL n 
1 415 ILE n 
1 416 ASP n 
1 417 PRO n 
1 418 LEU n 
1 419 ILE n 
1 420 TYR n 
1 421 ALA n 
1 422 PHE n 
1 423 ARG n 
1 424 SER n 
1 425 LEU n 
1 426 GLU n 
1 427 LEU n 
1 428 ARG n 
1 429 ASN n 
1 430 THR n 
1 431 PHE n 
1 432 ARG n 
1 433 GLU n 
1 434 ILE n 
1 435 LEU n 
1 436 CYS n 
1 437 GLY n 
1 438 CYS n 
1 439 ASN n 
1 440 GLY n 
1 441 MET n 
1 442 ASN n 
1 443 LEU n 
1 444 GLY n 
1 445 VAL n 
1 446 PHE n 
1 447 THR n 
1 448 LEU n 
1 449 GLU n 
1 450 ASP n 
1 451 PHE n 
1 452 VAL n 
1 453 GLY n 
1 454 ASP n 
1 455 TRP n 
1 456 GLU n 
1 457 GLN n 
1 458 THR n 
1 459 ALA n 
1 460 ALA n 
1 461 TYR n 
1 462 ASN n 
1 463 LEU n 
1 464 ASP n 
1 465 GLN n 
1 466 VAL n 
1 467 LEU n 
1 468 GLU n 
1 469 GLN n 
1 470 GLY n 
1 471 GLY n 
1 472 VAL n 
1 473 SER n 
1 474 SER n 
1 475 LEU n 
1 476 LEU n 
1 477 GLN n 
1 478 ASN n 
1 479 LEU n 
1 480 ALA n 
1 481 VAL n 
1 482 SER n 
1 483 VAL n 
1 484 THR n 
1 485 PRO n 
1 486 ILE n 
1 487 GLN n 
1 488 ARG n 
1 489 ILE n 
1 490 VAL n 
1 491 ARG n 
1 492 SER n 
1 493 GLY n 
1 494 GLU n 
1 495 ASN n 
1 496 ALA n 
1 497 LEU n 
1 498 LYS n 
1 499 ILE n 
1 500 ASP n 
1 501 ILE n 
1 502 HIS n 
1 503 VAL n 
1 504 ILE n 
1 505 ILE n 
1 506 PRO n 
1 507 TYR n 
1 508 GLU n 
1 509 GLY n 
1 510 LEU n 
1 511 SER n 
1 512 ALA n 
1 513 ASP n 
1 514 GLN n 
1 515 MET n 
1 516 ALA n 
1 517 GLN n 
1 518 ILE n 
1 519 GLU n 
1 520 GLU n 
1 521 VAL n 
1 522 PHE n 
1 523 LYS n 
1 524 VAL n 
1 525 VAL n 
1 526 TYR n 
1 527 PRO n 
1 528 VAL n 
1 529 ASP n 
1 530 ASP n 
1 531 HIS n 
1 532 HIS n 
1 533 PHE n 
1 534 LYS n 
1 535 VAL n 
1 536 ILE n 
1 537 LEU n 
1 538 PRO n 
1 539 TYR n 
1 540 GLY n 
1 541 THR n 
1 542 LEU n 
1 543 VAL n 
1 544 ILE n 
1 545 ASP n 
1 546 GLY n 
1 547 VAL n 
1 548 THR n 
1 549 PRO n 
1 550 ASN n 
1 551 MET n 
1 552 LEU n 
1 553 ASN n 
1 554 TYR n 
1 555 PHE n 
1 556 GLY n 
1 557 ARG n 
1 558 PRO n 
1 559 TYR n 
1 560 GLU n 
1 561 GLY n 
1 562 ILE n 
1 563 ALA n 
1 564 VAL n 
1 565 PHE n 
1 566 ASP n 
1 567 GLY n 
1 568 LYS n 
1 569 LYS n 
1 570 ILE n 
1 571 THR n 
1 572 VAL n 
1 573 THR n 
1 574 GLY n 
1 575 THR n 
1 576 LEU n 
1 577 TRP n 
1 578 ASN n 
1 579 GLY n 
1 580 ASN n 
1 581 LYS n 
1 582 ILE n 
1 583 ILE n 
1 584 ASP n 
1 585 GLU n 
1 586 ARG n 
1 587 LEU n 
1 588 ILE n 
1 589 THR n 
1 590 PRO n 
1 591 ASP n 
1 592 GLY n 
1 593 SER n 
1 594 MET n 
1 595 LEU n 
1 596 PHE n 
1 597 ARG n 
1 598 VAL n 
1 599 THR n 
1 600 ILE n 
1 601 ASN n 
1 602 SER n 
2 1   MET n 
2 2   HIS n 
2 3   HIS n 
2 4   HIS n 
2 5   HIS n 
2 6   HIS n 
2 7   HIS n 
2 8   LEU n 
2 9   GLU n 
2 10  VAL n 
2 11  LEU n 
2 12  PHE n 
2 13  GLN n 
2 14  GLY n 
2 15  PRO n 
2 16  GLY n 
2 17  SER n 
2 18  SER n 
2 19  GLY n 
2 20  SER n 
2 21  GLU n 
2 22  LEU n 
2 23  ASP n 
2 24  GLN n 
2 25  LEU n 
2 26  ARG n 
2 27  GLN n 
2 28  GLU n 
2 29  ALA n 
2 30  GLU n 
2 31  GLN n 
2 32  LEU n 
2 33  LYS n 
2 34  ASN n 
2 35  GLN n 
2 36  ILE n 
2 37  ARG n 
2 38  ASP n 
2 39  ALA n 
2 40  ARG n 
2 41  LYS n 
2 42  ALA n 
2 43  CYS n 
2 44  ALA n 
2 45  ASP n 
2 46  ALA n 
2 47  THR n 
2 48  LEU n 
2 49  SER n 
2 50  GLN n 
2 51  ILE n 
2 52  THR n 
2 53  ASN n 
2 54  ASN n 
2 55  ILE n 
2 56  ASP n 
2 57  PRO n 
2 58  VAL n 
2 59  GLY n 
2 60  ARG n 
2 61  ILE n 
2 62  GLN n 
2 63  MET n 
2 64  ARG n 
2 65  THR n 
2 66  ARG n 
2 67  ARG n 
2 68  THR n 
2 69  LEU n 
2 70  ARG n 
2 71  GLY n 
2 72  HIS n 
2 73  LEU n 
2 74  ALA n 
2 75  LYS n 
2 76  ILE n 
2 77  TYR n 
2 78  ALA n 
2 79  MET n 
2 80  HIS n 
2 81  TRP n 
2 82  GLY n 
2 83  THR n 
2 84  ASP n 
2 85  SER n 
2 86  ARG n 
2 87  LEU n 
2 88  LEU n 
2 89  VAL n 
2 90  SER n 
2 91  ALA n 
2 92  SER n 
2 93  GLN n 
2 94  ASP n 
2 95  GLY n 
2 96  LYS n 
2 97  LEU n 
2 98  ILE n 
2 99  ILE n 
2 100 TRP n 
2 101 ASP n 
2 102 SER n 
2 103 TYR n 
2 104 THR n 
2 105 THR n 
2 106 ASN n 
2 107 LYS n 
2 108 VAL n 
2 109 HIS n 
2 110 ALA n 
2 111 ILE n 
2 112 PRO n 
2 113 LEU n 
2 114 ARG n 
2 115 SER n 
2 116 SER n 
2 117 TRP n 
2 118 VAL n 
2 119 MET n 
2 120 THR n 
2 121 CYS n 
2 122 ALA n 
2 123 TYR n 
2 124 ALA n 
2 125 PRO n 
2 126 SER n 
2 127 GLY n 
2 128 ASN n 
2 129 TYR n 
2 130 VAL n 
2 131 ALA n 
2 132 CYS n 
2 133 GLY n 
2 134 GLY n 
2 135 LEU n 
2 136 ASP n 
2 137 ASN n 
2 138 ILE n 
2 139 CYS n 
2 140 SER n 
2 141 ILE n 
2 142 TYR n 
2 143 ASN n 
2 144 LEU n 
2 145 LYS n 
2 146 THR n 
2 147 ARG n 
2 148 GLU n 
2 149 GLY n 
2 150 ASN n 
2 151 VAL n 
2 152 ARG n 
2 153 VAL n 
2 154 SER n 
2 155 ARG n 
2 156 GLU n 
2 157 LEU n 
2 158 ALA n 
2 159 GLY n 
2 160 HIS n 
2 161 THR n 
2 162 GLY n 
2 163 TYR n 
2 164 LEU n 
2 165 SER n 
2 166 CYS n 
2 167 CYS n 
2 168 ARG n 
2 169 PHE n 
2 170 LEU n 
2 171 ASP n 
2 172 ASP n 
2 173 ASN n 
2 174 GLN n 
2 175 ILE n 
2 176 VAL n 
2 177 THR n 
2 178 SER n 
2 179 SER n 
2 180 GLY n 
2 181 ASP n 
2 182 THR n 
2 183 THR n 
2 184 CYS n 
2 185 ALA n 
2 186 LEU n 
2 187 TRP n 
2 188 ASP n 
2 189 ILE n 
2 190 GLU n 
2 191 THR n 
2 192 GLY n 
2 193 GLN n 
2 194 GLN n 
2 195 THR n 
2 196 THR n 
2 197 THR n 
2 198 PHE n 
2 199 THR n 
2 200 GLY n 
2 201 HIS n 
2 202 THR n 
2 203 GLY n 
2 204 ASP n 
2 205 VAL n 
2 206 MET n 
2 207 SER n 
2 208 LEU n 
2 209 SER n 
2 210 LEU n 
2 211 ALA n 
2 212 PRO n 
2 213 ASP n 
2 214 THR n 
2 215 ARG n 
2 216 LEU n 
2 217 PHE n 
2 218 VAL n 
2 219 SER n 
2 220 GLY n 
2 221 ALA n 
2 222 CYS n 
2 223 ASP n 
2 224 ALA n 
2 225 SER n 
2 226 ALA n 
2 227 LYS n 
2 228 LEU n 
2 229 TRP n 
2 230 ASP n 
2 231 VAL n 
2 232 ARG n 
2 233 GLU n 
2 234 GLY n 
2 235 MET n 
2 236 CYS n 
2 237 ARG n 
2 238 GLN n 
2 239 THR n 
2 240 PHE n 
2 241 THR n 
2 242 GLY n 
2 243 HIS n 
2 244 GLU n 
2 245 SER n 
2 246 ASP n 
2 247 ILE n 
2 248 ASN n 
2 249 ALA n 
2 250 ILE n 
2 251 CYS n 
2 252 PHE n 
2 253 PHE n 
2 254 PRO n 
2 255 ASN n 
2 256 GLY n 
2 257 ASN n 
2 258 ALA n 
2 259 PHE n 
2 260 ALA n 
2 261 THR n 
2 262 GLY n 
2 263 SER n 
2 264 ASP n 
2 265 ASP n 
2 266 ALA n 
2 267 THR n 
2 268 CYS n 
2 269 ARG n 
2 270 LEU n 
2 271 PHE n 
2 272 ASP n 
2 273 LEU n 
2 274 ARG n 
2 275 ALA n 
2 276 ASP n 
2 277 GLN n 
2 278 GLU n 
2 279 LEU n 
2 280 MET n 
2 281 THR n 
2 282 TYR n 
2 283 SER n 
2 284 HIS n 
2 285 ASP n 
2 286 ASN n 
2 287 ILE n 
2 288 ILE n 
2 289 CYS n 
2 290 GLY n 
2 291 ILE n 
2 292 THR n 
2 293 SER n 
2 294 VAL n 
2 295 SER n 
2 296 PHE n 
2 297 SER n 
2 298 LYS n 
2 299 SER n 
2 300 GLY n 
2 301 ARG n 
2 302 LEU n 
2 303 LEU n 
2 304 LEU n 
2 305 ALA n 
2 306 GLY n 
2 307 TYR n 
2 308 ASP n 
2 309 ASP n 
2 310 PHE n 
2 311 ASN n 
2 312 CYS n 
2 313 ASN n 
2 314 VAL n 
2 315 TRP n 
2 316 ASP n 
2 317 ALA n 
2 318 LEU n 
2 319 LYS n 
2 320 ALA n 
2 321 ASP n 
2 322 ARG n 
2 323 ALA n 
2 324 GLY n 
2 325 VAL n 
2 326 LEU n 
2 327 ALA n 
2 328 GLY n 
2 329 HIS n 
2 330 ASP n 
2 331 ASN n 
2 332 ARG n 
2 333 VAL n 
2 334 SER n 
2 335 CYS n 
2 336 LEU n 
2 337 GLY n 
2 338 VAL n 
2 339 THR n 
2 340 ASP n 
2 341 ASP n 
2 342 GLY n 
2 343 MET n 
2 344 ALA n 
2 345 VAL n 
2 346 ALA n 
2 347 THR n 
2 348 GLY n 
2 349 SER n 
2 350 TRP n 
2 351 ASP n 
2 352 SER n 
2 353 PHE n 
2 354 LEU n 
2 355 LYS n 
2 356 ILE n 
2 357 TRP n 
2 358 ASN n 
2 359 GLY n 
2 360 SER n 
2 361 SER n 
2 362 GLY n 
2 363 GLY n 
2 364 GLY n 
2 365 GLY n 
2 366 SER n 
2 367 GLY n 
2 368 GLY n 
2 369 GLY n 
2 370 GLY n 
2 371 SER n 
2 372 SER n 
2 373 GLY n 
2 374 VAL n 
2 375 SER n 
2 376 GLY n 
2 377 TRP n 
2 378 ARG n 
2 379 LEU n 
2 380 PHE n 
2 381 LYS n 
2 382 LYS n 
2 383 ILE n 
2 384 SER n 
3 1   MET n 
3 2   ALA n 
3 3   SER n 
3 4   ASN n 
3 5   ASN n 
3 6   THR n 
3 7   ALA n 
3 8   SER n 
3 9   ILE n 
3 10  ALA n 
3 11  GLN n 
3 12  ALA n 
3 13  ARG n 
3 14  LYS n 
3 15  LEU n 
3 16  VAL n 
3 17  GLU n 
3 18  GLN n 
3 19  LEU n 
3 20  LYS n 
3 21  MET n 
3 22  GLU n 
3 23  ALA n 
3 24  ASN n 
3 25  ILE n 
3 26  ASP n 
3 27  ARG n 
3 28  ILE n 
3 29  LYS n 
3 30  VAL n 
3 31  SER n 
3 32  LYS n 
3 33  ALA n 
3 34  ALA n 
3 35  ALA n 
3 36  ASP n 
3 37  LEU n 
3 38  MET n 
3 39  ALA n 
3 40  TYR n 
3 41  CYS n 
3 42  GLU n 
3 43  ALA n 
3 44  HIS n 
3 45  ALA n 
3 46  LYS n 
3 47  GLU n 
3 48  ASP n 
3 49  PRO n 
3 50  LEU n 
3 51  LEU n 
3 52  THR n 
3 53  PRO n 
3 54  VAL n 
3 55  PRO n 
3 56  ALA n 
3 57  SER n 
3 58  GLU n 
3 59  ASN n 
3 60  PRO n 
3 61  PHE n 
3 62  ARG n 
3 63  GLU n 
3 64  LYS n 
3 65  LYS n 
3 66  PHE n 
3 67  PHE n 
3 68  CYS n 
3 69  ALA n 
3 70  ILE n 
3 71  LEU n 
4 1   MET n 
4 2   LYS n 
4 3   TYR n 
4 4   LEU n 
4 5   LEU n 
4 6   PRO n 
4 7   THR n 
4 8   ALA n 
4 9   ALA n 
4 10  ALA n 
4 11  GLY n 
4 12  LEU n 
4 13  LEU n 
4 14  LEU n 
4 15  LEU n 
4 16  ALA n 
4 17  ALA n 
4 18  GLN n 
4 19  PRO n 
4 20  ALA n 
4 21  MET n 
4 22  ALA n 
4 23  GLN n 
4 24  VAL n 
4 25  GLN n 
4 26  LEU n 
4 27  GLN n 
4 28  GLU n 
4 29  SER n 
4 30  GLY n 
4 31  GLY n 
4 32  GLY n 
4 33  LEU n 
4 34  VAL n 
4 35  GLN n 
4 36  PRO n 
4 37  GLY n 
4 38  GLY n 
4 39  SER n 
4 40  LEU n 
4 41  ARG n 
4 42  LEU n 
4 43  SER n 
4 44  CYS n 
4 45  ALA n 
4 46  ALA n 
4 47  SER n 
4 48  GLY n 
4 49  PHE n 
4 50  THR n 
4 51  PHE n 
4 52  SER n 
4 53  ASN n 
4 54  TYR n 
4 55  LYS n 
4 56  MET n 
4 57  ASN n 
4 58  TRP n 
4 59  VAL n 
4 60  ARG n 
4 61  GLN n 
4 62  ALA n 
4 63  PRO n 
4 64  GLY n 
4 65  LYS n 
4 66  GLY n 
4 67  LEU n 
4 68  GLU n 
4 69  TRP n 
4 70  VAL n 
4 71  SER n 
4 72  ASP n 
4 73  ILE n 
4 74  SER n 
4 75  GLN n 
4 76  SER n 
4 77  GLY n 
4 78  ALA n 
4 79  SER n 
4 80  ILE n 
4 81  SER n 
4 82  TYR n 
4 83  THR n 
4 84  GLY n 
4 85  SER n 
4 86  VAL n 
4 87  LYS n 
4 88  GLY n 
4 89  ARG n 
4 90  PHE n 
4 91  THR n 
4 92  ILE n 
4 93  SER n 
4 94  ARG n 
4 95  ASP n 
4 96  ASN n 
4 97  ALA n 
4 98  LYS n 
4 99  ASN n 
4 100 THR n 
4 101 LEU n 
4 102 TYR n 
4 103 LEU n 
4 104 GLN n 
4 105 MET n 
4 106 ASN n 
4 107 SER n 
4 108 LEU n 
4 109 LYS n 
4 110 PRO n 
4 111 GLU n 
4 112 ASP n 
4 113 THR n 
4 114 ALA n 
4 115 VAL n 
4 116 TYR n 
4 117 TYR n 
4 118 CYS n 
4 119 ALA n 
4 120 ARG n 
4 121 CYS n 
4 122 PRO n 
4 123 ALA n 
4 124 PRO n 
4 125 PHE n 
4 126 THR n 
4 127 ARG n 
4 128 ASP n 
4 129 CYS n 
4 130 PHE n 
4 131 ASP n 
4 132 VAL n 
4 133 THR n 
4 134 SER n 
4 135 THR n 
4 136 THR n 
4 137 TYR n 
4 138 ALA n 
4 139 TYR n 
4 140 ARG n 
4 141 GLY n 
4 142 GLN n 
4 143 GLY n 
4 144 THR n 
4 145 GLN n 
4 146 VAL n 
4 147 THR n 
4 148 VAL n 
4 149 SER n 
4 150 SER n 
4 151 HIS n 
4 152 HIS n 
4 153 HIS n 
4 154 HIS n 
4 155 HIS n 
4 156 HIS n 
4 157 GLU n 
4 158 PRO n 
4 159 GLU n 
4 160 ALA n 
5 1   SER n 
5 2   TYR n 
5 3   SER n 
5 4   MET n 
5 5   GLU n 
5 6   HIS n 
5 7   PHE n 
5 8   ARG n 
5 9   TRP n 
5 10  GLY n 
5 11  LYS n 
5 12  PRO n 
5 13  VAL n 
6 1   MET n 
6 2   GLY n 
6 3   CYS n 
6 4   LEU n 
6 5   GLY n 
6 6   ASN n 
6 7   SER n 
6 8   LYS n 
6 9   THR n 
6 10  GLU n 
6 11  ASP n 
6 12  GLN n 
6 13  ARG n 
6 14  ASN n 
6 15  GLU n 
6 16  GLU n 
6 17  LYS n 
6 18  ALA n 
6 19  GLN n 
6 20  ARG n 
6 21  GLU n 
6 22  ALA n 
6 23  ASN n 
6 24  LYS n 
6 25  LYS n 
6 26  ILE n 
6 27  GLU n 
6 28  LYS n 
6 29  GLN n 
6 30  LEU n 
6 31  GLN n 
6 32  LYS n 
6 33  ASP n 
6 34  LYS n 
6 35  GLN n 
6 36  VAL n 
6 37  TYR n 
6 38  ARG n 
6 39  ALA n 
6 40  THR n 
6 41  HIS n 
6 42  ARG n 
6 43  LEU n 
6 44  LEU n 
6 45  LEU n 
6 46  LEU n 
6 47  GLY n 
6 48  ALA n 
6 49  GLY n 
6 50  GLU n 
6 51  SER n 
6 52  GLY n 
6 53  LYS n 
6 54  SER n 
6 55  THR n 
6 56  ILE n 
6 57  VAL n 
6 58  LYS n 
6 59  GLN n 
6 60  MET n 
6 61  ARG n 
6 62  ILE n 
6 63  LEU n 
6 64  HIS n 
6 65  VAL n 
6 66  ASN n 
6 67  GLY n 
6 68  PHE n 
6 69  ASN n 
6 70  GLY n 
6 71  ASP n 
6 72  SER n 
6 73  GLU n 
6 74  LYS n 
6 75  ALA n 
6 76  THR n 
6 77  LYS n 
6 78  VAL n 
6 79  GLN n 
6 80  ASP n 
6 81  ILE n 
6 82  LYS n 
6 83  ASN n 
6 84  ASN n 
6 85  LEU n 
6 86  LYS n 
6 87  GLU n 
6 88  ALA n 
6 89  ILE n 
6 90  GLU n 
6 91  THR n 
6 92  ILE n 
6 93  VAL n 
6 94  ALA n 
6 95  ALA n 
6 96  MET n 
6 97  SER n 
6 98  ASN n 
6 99  LEU n 
6 100 VAL n 
6 101 PRO n 
6 102 PRO n 
6 103 VAL n 
6 104 GLU n 
6 105 LEU n 
6 106 ALA n 
6 107 ASN n 
6 108 PRO n 
6 109 GLU n 
6 110 ASN n 
6 111 GLN n 
6 112 PHE n 
6 113 ARG n 
6 114 VAL n 
6 115 ASP n 
6 116 TYR n 
6 117 ILE n 
6 118 LEU n 
6 119 SER n 
6 120 VAL n 
6 121 MET n 
6 122 ASN n 
6 123 VAL n 
6 124 PRO n 
6 125 ASP n 
6 126 PHE n 
6 127 ASP n 
6 128 PHE n 
6 129 PRO n 
6 130 PRO n 
6 131 GLU n 
6 132 PHE n 
6 133 TYR n 
6 134 GLU n 
6 135 HIS n 
6 136 ALA n 
6 137 LYS n 
6 138 ALA n 
6 139 LEU n 
6 140 TRP n 
6 141 GLU n 
6 142 ASP n 
6 143 GLU n 
6 144 GLY n 
6 145 VAL n 
6 146 ARG n 
6 147 ALA n 
6 148 CYS n 
6 149 TYR n 
6 150 GLU n 
6 151 ARG n 
6 152 SER n 
6 153 ASN n 
6 154 GLU n 
6 155 TYR n 
6 156 GLN n 
6 157 LEU n 
6 158 ILE n 
6 159 ASP n 
6 160 CYS n 
6 161 ALA n 
6 162 GLN n 
6 163 TYR n 
6 164 PHE n 
6 165 LEU n 
6 166 ASP n 
6 167 LYS n 
6 168 ILE n 
6 169 ASP n 
6 170 VAL n 
6 171 ILE n 
6 172 LYS n 
6 173 GLN n 
6 174 ALA n 
6 175 ASP n 
6 176 TYR n 
6 177 VAL n 
6 178 PRO n 
6 179 SER n 
6 180 ASP n 
6 181 GLN n 
6 182 ASP n 
6 183 LEU n 
6 184 LEU n 
6 185 ARG n 
6 186 CYS n 
6 187 ARG n 
6 188 VAL n 
6 189 LEU n 
6 190 THR n 
6 191 SER n 
6 192 GLY n 
6 193 ILE n 
6 194 PHE n 
6 195 GLU n 
6 196 THR n 
6 197 LYS n 
6 198 PHE n 
6 199 GLN n 
6 200 VAL n 
6 201 ASP n 
6 202 LYS n 
6 203 VAL n 
6 204 ASN n 
6 205 PHE n 
6 206 HIS n 
6 207 MET n 
6 208 PHE n 
6 209 ASP n 
6 210 VAL n 
6 211 GLY n 
6 212 GLY n 
6 213 GLN n 
6 214 ARG n 
6 215 ASP n 
6 216 GLU n 
6 217 ARG n 
6 218 ARG n 
6 219 LYS n 
6 220 TRP n 
6 221 ILE n 
6 222 GLN n 
6 223 CYS n 
6 224 PHE n 
6 225 ASN n 
6 226 ASP n 
6 227 VAL n 
6 228 THR n 
6 229 ALA n 
6 230 ILE n 
6 231 ILE n 
6 232 PHE n 
6 233 VAL n 
6 234 VAL n 
6 235 ALA n 
6 236 SER n 
6 237 SER n 
6 238 SER n 
6 239 TYR n 
6 240 ASN n 
6 241 MET n 
6 242 VAL n 
6 243 ILE n 
6 244 ARG n 
6 245 GLU n 
6 246 ASP n 
6 247 ASN n 
6 248 GLN n 
6 249 THR n 
6 250 ASN n 
6 251 ARG n 
6 252 LEU n 
6 253 GLN n 
6 254 GLU n 
6 255 ALA n 
6 256 LEU n 
6 257 ASN n 
6 258 LEU n 
6 259 PHE n 
6 260 LYS n 
6 261 SER n 
6 262 ILE n 
6 263 TRP n 
6 264 ASN n 
6 265 ASN n 
6 266 ARG n 
6 267 TRP n 
6 268 LEU n 
6 269 ARG n 
6 270 THR n 
6 271 ILE n 
6 272 SER n 
6 273 VAL n 
6 274 ILE n 
6 275 LEU n 
6 276 PHE n 
6 277 LEU n 
6 278 ASN n 
6 279 LYS n 
6 280 GLN n 
6 281 ASP n 
6 282 LEU n 
6 283 LEU n 
6 284 ALA n 
6 285 GLU n 
6 286 LYS n 
6 287 VAL n 
6 288 LEU n 
6 289 ALA n 
6 290 GLY n 
6 291 LYS n 
6 292 SER n 
6 293 LYS n 
6 294 ILE n 
6 295 GLU n 
6 296 ASP n 
6 297 TYR n 
6 298 PHE n 
6 299 PRO n 
6 300 GLU n 
6 301 PHE n 
6 302 ALA n 
6 303 ARG n 
6 304 TYR n 
6 305 THR n 
6 306 THR n 
6 307 PRO n 
6 308 GLU n 
6 309 ASP n 
6 310 ALA n 
6 311 THR n 
6 312 PRO n 
6 313 GLU n 
6 314 PRO n 
6 315 GLY n 
6 316 GLU n 
6 317 ASP n 
6 318 PRO n 
6 319 ARG n 
6 320 VAL n 
6 321 THR n 
6 322 ARG n 
6 323 ALA n 
6 324 LYS n 
6 325 TYR n 
6 326 PHE n 
6 327 ILE n 
6 328 ARG n 
6 329 ASP n 
6 330 GLU n 
6 331 PHE n 
6 332 LEU n 
6 333 ARG n 
6 334 ILE n 
6 335 SER n 
6 336 THR n 
6 337 ALA n 
6 338 SER n 
6 339 GLY n 
6 340 ASP n 
6 341 GLY n 
6 342 ARG n 
6 343 HIS n 
6 344 TYR n 
6 345 CYS n 
6 346 TYR n 
6 347 PRO n 
6 348 HIS n 
6 349 PHE n 
6 350 THR n 
6 351 CYS n 
6 352 ALA n 
6 353 VAL n 
6 354 ASP n 
6 355 THR n 
6 356 GLU n 
6 357 ASN n 
6 358 ILE n 
6 359 ARG n 
6 360 ARG n 
6 361 VAL n 
6 362 PHE n 
6 363 ASN n 
6 364 ASP n 
6 365 CYS n 
6 366 ARG n 
6 367 ASP n 
6 368 ILE n 
6 369 ILE n 
6 370 GLN n 
6 371 ARG n 
6 372 MET n 
6 373 HIS n 
6 374 LEU n 
6 375 ARG n 
6 376 GLN n 
6 377 TYR n 
6 378 GLU n 
6 379 LEU n 
6 380 LEU n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1   122 ?            ? cybC               ? ? ? ? ? ? 'Escherichia coli'  562   ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda' 7108    ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
1 2 sample 'Biological sequence' 123 444 human        ? MC3R               ? ? ? ? ? ? 'Homo sapiens'      9606  ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda' 7108    ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
1 3 sample 'Biological sequence' 445 602 human        ? ?                  ? ? ? ? ? ? 'Homo sapiens'      9606  ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda' 7108    ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1   384 'Norway rat' ? Gnb1               ? ? ? ? ? ? 'Rattus norvegicus' 10116 ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda' 7108    ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1   71  cattle       ? GNG2               ? ? ? ? ? ? 'Bos taurus'        9913  ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda' 7108    ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
4 1 sample 'Biological sequence' 1   160 ?            ? ?                  ? ? ? ? ? ? 'Lama glama'        9844  ? ? ? ? ? ? ? ? 
Eschenbachia            1408200 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
6 1 sample 'Biological sequence' 1   380 human        ? 'GNAS, GNAS1, GSP' ? ? ? ? ? ? 'Homo sapiens'      9606  ? ? ? ? ? ? ? ? 
'Spodoptera frugiperda' 7108    ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
_pdbx_entity_src_syn.entity_id              5 
_pdbx_entity_src_syn.pdbx_src_id            1 
_pdbx_entity_src_syn.pdbx_alt_source_flag   sample 
_pdbx_entity_src_syn.pdbx_beg_seq_num       1 
_pdbx_entity_src_syn.pdbx_end_seq_num       13 
_pdbx_entity_src_syn.organism_scientific    'Homo sapiens' 
_pdbx_entity_src_syn.organism_common_name   ? 
_pdbx_entity_src_syn.ncbi_taxonomy_id       9606 
_pdbx_entity_src_syn.details                ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CA  non-polymer         . 'CALCIUM ION'   ? 'Ca 2'           40.078  
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   ASP 1   -120 ?   ?   ?   R . n 
A 1 2   TYR 2   -119 ?   ?   ?   R . n 
A 1 3   LYS 3   -118 ?   ?   ?   R . n 
A 1 4   ASP 4   -117 ?   ?   ?   R . n 
A 1 5   ASP 5   -116 ?   ?   ?   R . n 
A 1 6   ASP 6   -115 ?   ?   ?   R . n 
A 1 7   ASP 7   -114 ?   ?   ?   R . n 
A 1 8   LYS 8   -113 ?   ?   ?   R . n 
A 1 9   GLY 9   -112 ?   ?   ?   R . n 
A 1 10  SER 10  -111 ?   ?   ?   R . n 
A 1 11  ALA 11  -110 ?   ?   ?   R . n 
A 1 12  ASP 12  -109 ?   ?   ?   R . n 
A 1 13  LEU 13  -108 ?   ?   ?   R . n 
A 1 14  GLU 14  -107 ?   ?   ?   R . n 
A 1 15  ASP 15  -106 ?   ?   ?   R . n 
A 1 16  ASN 16  -105 ?   ?   ?   R . n 
A 1 17  TRP 17  -104 ?   ?   ?   R . n 
A 1 18  GLU 18  -103 ?   ?   ?   R . n 
A 1 19  THR 19  -102 ?   ?   ?   R . n 
A 1 20  LEU 20  -101 ?   ?   ?   R . n 
A 1 21  ASN 21  -100 ?   ?   ?   R . n 
A 1 22  ASP 22  -99  ?   ?   ?   R . n 
A 1 23  ASN 23  -98  ?   ?   ?   R . n 
A 1 24  LEU 24  -97  ?   ?   ?   R . n 
A 1 25  LYS 25  -96  ?   ?   ?   R . n 
A 1 26  VAL 26  -95  ?   ?   ?   R . n 
A 1 27  ILE 27  -94  ?   ?   ?   R . n 
A 1 28  GLU 28  -93  ?   ?   ?   R . n 
A 1 29  LYS 29  -92  ?   ?   ?   R . n 
A 1 30  ALA 30  -91  ?   ?   ?   R . n 
A 1 31  ASP 31  -90  ?   ?   ?   R . n 
A 1 32  ASN 32  -89  ?   ?   ?   R . n 
A 1 33  ALA 33  -88  ?   ?   ?   R . n 
A 1 34  ALA 34  -87  ?   ?   ?   R . n 
A 1 35  GLN 35  -86  ?   ?   ?   R . n 
A 1 36  VAL 36  -85  ?   ?   ?   R . n 
A 1 37  LYS 37  -84  ?   ?   ?   R . n 
A 1 38  ASP 38  -83  ?   ?   ?   R . n 
A 1 39  ALA 39  -82  ?   ?   ?   R . n 
A 1 40  LEU 40  -81  ?   ?   ?   R . n 
A 1 41  THR 41  -80  ?   ?   ?   R . n 
A 1 42  LYS 42  -79  ?   ?   ?   R . n 
A 1 43  MET 43  -78  ?   ?   ?   R . n 
A 1 44  ARG 44  -77  ?   ?   ?   R . n 
A 1 45  ALA 45  -76  ?   ?   ?   R . n 
A 1 46  ALA 46  -75  ?   ?   ?   R . n 
A 1 47  ALA 47  -74  ?   ?   ?   R . n 
A 1 48  LEU 48  -73  ?   ?   ?   R . n 
A 1 49  ASP 49  -72  ?   ?   ?   R . n 
A 1 50  ALA 50  -71  ?   ?   ?   R . n 
A 1 51  GLN 51  -70  ?   ?   ?   R . n 
A 1 52  LYS 52  -69  ?   ?   ?   R . n 
A 1 53  ALA 53  -68  ?   ?   ?   R . n 
A 1 54  THR 54  -67  ?   ?   ?   R . n 
A 1 55  PRO 55  -66  ?   ?   ?   R . n 
A 1 56  PRO 56  -65  ?   ?   ?   R . n 
A 1 57  LYS 57  -64  ?   ?   ?   R . n 
A 1 58  LEU 58  -63  ?   ?   ?   R . n 
A 1 59  GLU 59  -62  ?   ?   ?   R . n 
A 1 60  ASP 60  -61  ?   ?   ?   R . n 
A 1 61  LYS 61  -60  ?   ?   ?   R . n 
A 1 62  SER 62  -59  ?   ?   ?   R . n 
A 1 63  PRO 63  -58  ?   ?   ?   R . n 
A 1 64  ASP 64  -57  ?   ?   ?   R . n 
A 1 65  SER 65  -56  ?   ?   ?   R . n 
A 1 66  PRO 66  -55  ?   ?   ?   R . n 
A 1 67  GLU 67  -54  ?   ?   ?   R . n 
A 1 68  MET 68  -53  ?   ?   ?   R . n 
A 1 69  LYS 69  -52  ?   ?   ?   R . n 
A 1 70  ASP 70  -51  ?   ?   ?   R . n 
A 1 71  PHE 71  -50  ?   ?   ?   R . n 
A 1 72  ARG 72  -49  ?   ?   ?   R . n 
A 1 73  HIS 73  -48  ?   ?   ?   R . n 
A 1 74  GLY 74  -47  ?   ?   ?   R . n 
A 1 75  PHE 75  -46  ?   ?   ?   R . n 
A 1 76  ASP 76  -45  ?   ?   ?   R . n 
A 1 77  ILE 77  -44  ?   ?   ?   R . n 
A 1 78  LEU 78  -43  ?   ?   ?   R . n 
A 1 79  VAL 79  -42  ?   ?   ?   R . n 
A 1 80  GLY 80  -41  ?   ?   ?   R . n 
A 1 81  GLN 81  -40  ?   ?   ?   R . n 
A 1 82  ILE 82  -39  ?   ?   ?   R . n 
A 1 83  ASP 83  -38  ?   ?   ?   R . n 
A 1 84  ASP 84  -37  ?   ?   ?   R . n 
A 1 85  ALA 85  -36  ?   ?   ?   R . n 
A 1 86  LEU 86  -35  ?   ?   ?   R . n 
A 1 87  LYS 87  -34  ?   ?   ?   R . n 
A 1 88  LEU 88  -33  ?   ?   ?   R . n 
A 1 89  ALA 89  -32  ?   ?   ?   R . n 
A 1 90  ASN 90  -31  ?   ?   ?   R . n 
A 1 91  GLU 91  -30  ?   ?   ?   R . n 
A 1 92  GLY 92  -29  ?   ?   ?   R . n 
A 1 93  LYS 93  -28  ?   ?   ?   R . n 
A 1 94  VAL 94  -27  ?   ?   ?   R . n 
A 1 95  LYS 95  -26  ?   ?   ?   R . n 
A 1 96  GLU 96  -25  ?   ?   ?   R . n 
A 1 97  ALA 97  -24  ?   ?   ?   R . n 
A 1 98  GLN 98  -23  ?   ?   ?   R . n 
A 1 99  ALA 99  -22  ?   ?   ?   R . n 
A 1 100 ALA 100 -21  ?   ?   ?   R . n 
A 1 101 ALA 101 -20  ?   ?   ?   R . n 
A 1 102 GLU 102 -19  ?   ?   ?   R . n 
A 1 103 GLN 103 -18  ?   ?   ?   R . n 
A 1 104 LEU 104 -17  ?   ?   ?   R . n 
A 1 105 LYS 105 -16  ?   ?   ?   R . n 
A 1 106 THR 106 -15  ?   ?   ?   R . n 
A 1 107 THR 107 -14  ?   ?   ?   R . n 
A 1 108 ARG 108 -13  ?   ?   ?   R . n 
A 1 109 ASN 109 -12  ?   ?   ?   R . n 
A 1 110 ALA 110 -11  ?   ?   ?   R . n 
A 1 111 TYR 111 -10  ?   ?   ?   R . n 
A 1 112 ILE 112 -9   ?   ?   ?   R . n 
A 1 113 GLN 113 -8   ?   ?   ?   R . n 
A 1 114 LYS 114 -7   ?   ?   ?   R . n 
A 1 115 TYR 115 -6   ?   ?   ?   R . n 
A 1 116 LEU 116 -5   ?   ?   ?   R . n 
A 1 117 LEU 117 -4   ?   ?   ?   R . n 
A 1 118 VAL 118 -3   ?   ?   ?   R . n 
A 1 119 PRO 119 -2   ?   ?   ?   R . n 
A 1 120 ARG 120 -1   ?   ?   ?   R . n 
A 1 121 GLY 121 0    ?   ?   ?   R . n 
A 1 122 SER 122 1    ?   ?   ?   R . n 
A 1 123 ASN 123 2    ?   ?   ?   R . n 
A 1 124 ALA 124 3    ?   ?   ?   R . n 
A 1 125 SER 125 4    ?   ?   ?   R . n 
A 1 126 CYS 126 5    ?   ?   ?   R . n 
A 1 127 CYS 127 6    ?   ?   ?   R . n 
A 1 128 LEU 128 7    ?   ?   ?   R . n 
A 1 129 PRO 129 8    ?   ?   ?   R . n 
A 1 130 SER 130 9    ?   ?   ?   R . n 
A 1 131 VAL 131 10   ?   ?   ?   R . n 
A 1 132 GLN 132 11   ?   ?   ?   R . n 
A 1 133 PRO 133 12   ?   ?   ?   R . n 
A 1 134 THR 134 13   ?   ?   ?   R . n 
A 1 135 LEU 135 14   ?   ?   ?   R . n 
A 1 136 PRO 136 15   ?   ?   ?   R . n 
A 1 137 ASN 137 16   ?   ?   ?   R . n 
A 1 138 GLY 138 17   ?   ?   ?   R . n 
A 1 139 SER 139 18   ?   ?   ?   R . n 
A 1 140 GLU 140 19   ?   ?   ?   R . n 
A 1 141 HIS 141 20   ?   ?   ?   R . n 
A 1 142 LEU 142 21   ?   ?   ?   R . n 
A 1 143 GLN 143 22   ?   ?   ?   R . n 
A 1 144 ALA 144 23   ?   ?   ?   R . n 
A 1 145 PRO 145 24   ?   ?   ?   R . n 
A 1 146 PHE 146 25   ?   ?   ?   R . n 
A 1 147 PHE 147 26   ?   ?   ?   R . n 
A 1 148 SER 148 27   ?   ?   ?   R . n 
A 1 149 ASN 149 28   ?   ?   ?   R . n 
A 1 150 GLN 150 29   ?   ?   ?   R . n 
A 1 151 SER 151 30   ?   ?   ?   R . n 
A 1 152 SER 152 31   ?   ?   ?   R . n 
A 1 153 SER 153 32   ?   ?   ?   R . n 
A 1 154 ALA 154 33   ?   ?   ?   R . n 
A 1 155 PHE 155 34   ?   ?   ?   R . n 
A 1 156 CYS 156 35   ?   ?   ?   R . n 
A 1 157 GLU 157 36   ?   ?   ?   R . n 
A 1 158 GLN 158 37   ?   ?   ?   R . n 
A 1 159 VAL 159 38   38  VAL VAL R . n 
A 1 160 PHE 160 39   39  PHE PHE R . n 
A 1 161 ILE 161 40   40  ILE ILE R . n 
A 1 162 LYS 162 41   41  LYS LYS R . n 
A 1 163 PRO 163 42   42  PRO PRO R . n 
A 1 164 GLU 164 43   43  GLU GLU R . n 
A 1 165 VAL 165 44   44  VAL VAL R . n 
A 1 166 PHE 166 45   45  PHE PHE R . n 
A 1 167 LEU 167 46   46  LEU LEU R . n 
A 1 168 SER 168 47   47  SER SER R . n 
A 1 169 LEU 169 48   48  LEU LEU R . n 
A 1 170 GLY 170 49   49  GLY GLY R . n 
A 1 171 ILE 171 50   50  ILE ILE R . n 
A 1 172 VAL 172 51   51  VAL VAL R . n 
A 1 173 SER 173 52   52  SER SER R . n 
A 1 174 LEU 174 53   53  LEU LEU R . n 
A 1 175 LEU 175 54   54  LEU LEU R . n 
A 1 176 GLU 176 55   55  GLU GLU R . n 
A 1 177 ASN 177 56   56  ASN ASN R . n 
A 1 178 ILE 178 57   57  ILE ILE R . n 
A 1 179 LEU 179 58   58  LEU LEU R . n 
A 1 180 VAL 180 59   59  VAL VAL R . n 
A 1 181 ILE 181 60   60  ILE ILE R . n 
A 1 182 LEU 182 61   61  LEU LEU R . n 
A 1 183 ALA 183 62   62  ALA ALA R . n 
A 1 184 VAL 184 63   63  VAL VAL R . n 
A 1 185 VAL 185 64   64  VAL VAL R . n 
A 1 186 ARG 186 65   65  ARG ARG R . n 
A 1 187 ASN 187 66   66  ASN ASN R . n 
A 1 188 GLY 188 67   67  GLY GLY R . n 
A 1 189 ASN 189 68   68  ASN ASN R . n 
A 1 190 LEU 190 69   69  LEU LEU R . n 
A 1 191 HIS 191 70   70  HIS HIS R . n 
A 1 192 SER 192 71   71  SER SER R . n 
A 1 193 PRO 193 72   72  PRO PRO R . n 
A 1 194 MET 194 73   73  MET MET R . n 
A 1 195 TYR 195 74   74  TYR TYR R . n 
A 1 196 PHE 196 75   75  PHE PHE R . n 
A 1 197 PHE 197 76   76  PHE PHE R . n 
A 1 198 LEU 198 77   77  LEU LEU R . n 
A 1 199 CYS 199 78   78  CYS CYS R . n 
A 1 200 SER 200 79   79  SER SER R . n 
A 1 201 LEU 201 80   80  LEU LEU R . n 
A 1 202 ALA 202 81   81  ALA ALA R . n 
A 1 203 VAL 203 82   82  VAL VAL R . n 
A 1 204 ALA 204 83   83  ALA ALA R . n 
A 1 205 ASP 205 84   84  ASP ASP R . n 
A 1 206 MET 206 85   85  MET MET R . n 
A 1 207 LEU 207 86   86  LEU LEU R . n 
A 1 208 VAL 208 87   87  VAL VAL R . n 
A 1 209 SER 209 88   88  SER SER R . n 
A 1 210 VAL 210 89   89  VAL VAL R . n 
A 1 211 SER 211 90   90  SER SER R . n 
A 1 212 ASN 212 91   91  ASN ASN R . n 
A 1 213 ALA 213 92   92  ALA ALA R . n 
A 1 214 LEU 214 93   93  LEU LEU R . n 
A 1 215 GLU 215 94   94  GLU GLU R . n 
A 1 216 THR 216 95   95  THR THR R . n 
A 1 217 ILE 217 96   96  ILE ILE R . n 
A 1 218 MET 218 97   97  MET MET R . n 
A 1 219 ILE 219 98   98  ILE ILE R . n 
A 1 220 ALA 220 99   99  ALA ALA R . n 
A 1 221 ILE 221 100  100 ILE ILE R . n 
A 1 222 VAL 222 101  101 VAL VAL R . n 
A 1 223 HIS 223 102  102 HIS HIS R . n 
A 1 224 SER 224 103  103 SER SER R . n 
A 1 225 ASP 225 104  104 ASP ASP R . n 
A 1 226 TYR 226 105  105 TYR TYR R . n 
A 1 227 LEU 227 106  106 LEU LEU R . n 
A 1 228 THR 228 107  107 THR THR R . n 
A 1 229 PHE 229 108  108 PHE PHE R . n 
A 1 230 GLU 230 109  109 GLU GLU R . n 
A 1 231 ASP 231 110  110 ASP ASP R . n 
A 1 232 GLN 232 111  111 GLN GLN R . n 
A 1 233 PHE 233 112  112 PHE PHE R . n 
A 1 234 ILE 234 113  113 ILE ILE R . n 
A 1 235 GLN 235 114  114 GLN GLN R . n 
A 1 236 HIS 236 115  115 HIS HIS R . n 
A 1 237 MET 237 116  116 MET MET R . n 
A 1 238 ASP 238 117  117 ASP ASP R . n 
A 1 239 ASN 239 118  118 ASN ASN R . n 
A 1 240 ILE 240 119  119 ILE ILE R . n 
A 1 241 PHE 241 120  120 PHE PHE R . n 
A 1 242 ASP 242 121  121 ASP ASP R . n 
A 1 243 SER 243 122  122 SER SER R . n 
A 1 244 MET 244 123  123 MET MET R . n 
A 1 245 ILE 245 124  124 ILE ILE R . n 
A 1 246 CYS 246 125  125 CYS CYS R . n 
A 1 247 ILE 247 126  126 ILE ILE R . n 
A 1 248 SER 248 127  127 SER SER R . n 
A 1 249 LEU 249 128  128 LEU LEU R . n 
A 1 250 VAL 250 129  129 VAL VAL R . n 
A 1 251 ALA 251 130  130 ALA ALA R . n 
A 1 252 SER 252 131  131 SER SER R . n 
A 1 253 ILE 253 132  132 ILE ILE R . n 
A 1 254 CYS 254 133  133 CYS CYS R . n 
A 1 255 ASN 255 134  134 ASN ASN R . n 
A 1 256 LEU 256 135  135 LEU LEU R . n 
A 1 257 LEU 257 136  136 LEU LEU R . n 
A 1 258 ALA 258 137  137 ALA ALA R . n 
A 1 259 ILE 259 138  138 ILE ILE R . n 
A 1 260 ALA 260 139  139 ALA ALA R . n 
A 1 261 VAL 261 140  140 VAL VAL R . n 
A 1 262 ASP 262 141  141 ASP ASP R . n 
A 1 263 ARG 263 142  142 ARG ARG R . n 
A 1 264 TYR 264 143  143 TYR TYR R . n 
A 1 265 VAL 265 144  144 VAL VAL R . n 
A 1 266 THR 266 145  145 THR THR R . n 
A 1 267 ILE 267 146  146 ILE ILE R . n 
A 1 268 PHE 268 147  147 PHE PHE R . n 
A 1 269 TYR 269 148  148 TYR TYR R . n 
A 1 270 ALA 270 149  149 ALA ALA R . n 
A 1 271 LEU 271 150  150 LEU LEU R . n 
A 1 272 ARG 272 151  151 ARG ARG R . n 
A 1 273 TYR 273 152  152 TYR TYR R . n 
A 1 274 HIS 274 153  153 HIS HIS R . n 
A 1 275 SER 275 154  154 SER SER R . n 
A 1 276 ILE 276 155  155 ILE ILE R . n 
A 1 277 MET 277 156  156 MET MET R . n 
A 1 278 THR 278 157  157 THR THR R . n 
A 1 279 VAL 279 158  158 VAL VAL R . n 
A 1 280 ARG 280 159  159 ARG ARG R . n 
A 1 281 LYS 281 160  160 LYS LYS R . n 
A 1 282 ALA 282 161  161 ALA ALA R . n 
A 1 283 LEU 283 162  162 LEU LEU R . n 
A 1 284 THR 284 163  163 THR THR R . n 
A 1 285 LEU 285 164  164 LEU LEU R . n 
A 1 286 ILE 286 165  165 ILE ILE R . n 
A 1 287 VAL 287 166  166 VAL VAL R . n 
A 1 288 ALA 288 167  167 ALA ALA R . n 
A 1 289 ILE 289 168  168 ILE ILE R . n 
A 1 290 TRP 290 169  169 TRP TRP R . n 
A 1 291 VAL 291 170  170 VAL VAL R . n 
A 1 292 CYS 292 171  171 CYS CYS R . n 
A 1 293 CYS 293 172  172 CYS CYS R . n 
A 1 294 GLY 294 173  173 GLY GLY R . n 
A 1 295 VAL 295 174  174 VAL VAL R . n 
A 1 296 CYS 296 175  175 CYS CYS R . n 
A 1 297 GLY 297 176  176 GLY GLY R . n 
A 1 298 VAL 298 177  177 VAL VAL R . n 
A 1 299 VAL 299 178  178 VAL VAL R . n 
A 1 300 PHE 300 179  179 PHE PHE R . n 
A 1 301 ILE 301 180  180 ILE ILE R . n 
A 1 302 VAL 302 181  181 VAL VAL R . n 
A 1 303 TYR 303 182  182 TYR TYR R . n 
A 1 304 SER 304 183  183 SER SER R . n 
A 1 305 GLU 305 184  184 GLU GLU R . n 
A 1 306 SER 306 185  185 SER SER R . n 
A 1 307 LYS 307 186  186 LYS LYS R . n 
A 1 308 MET 308 187  187 MET MET R . n 
A 1 309 VAL 309 188  188 VAL VAL R . n 
A 1 310 ILE 310 189  189 ILE ILE R . n 
A 1 311 VAL 311 190  190 VAL VAL R . n 
A 1 312 CYS 312 191  191 CYS CYS R . n 
A 1 313 LEU 313 192  192 LEU LEU R . n 
A 1 314 ILE 314 193  193 ILE ILE R . n 
A 1 315 THR 315 194  194 THR THR R . n 
A 1 316 MET 316 195  195 MET MET R . n 
A 1 317 PHE 317 196  196 PHE PHE R . n 
A 1 318 PHE 318 197  197 PHE PHE R . n 
A 1 319 ALA 319 198  198 ALA ALA R . n 
A 1 320 MET 320 199  199 MET MET R . n 
A 1 321 MET 321 200  200 MET MET R . n 
A 1 322 LEU 322 201  201 LEU LEU R . n 
A 1 323 LEU 323 202  202 LEU LEU R . n 
A 1 324 MET 324 203  203 MET MET R . n 
A 1 325 GLY 325 204  204 GLY GLY R . n 
A 1 326 THR 326 205  205 THR THR R . n 
A 1 327 LEU 327 206  206 LEU LEU R . n 
A 1 328 TYR 328 207  207 TYR TYR R . n 
A 1 329 VAL 329 208  208 VAL VAL R . n 
A 1 330 HIS 330 209  209 HIS HIS R . n 
A 1 331 MET 331 210  210 MET MET R . n 
A 1 332 PHE 332 211  211 PHE PHE R . n 
A 1 333 LEU 333 212  212 LEU LEU R . n 
A 1 334 PHE 334 213  213 PHE PHE R . n 
A 1 335 ALA 335 214  214 ALA ALA R . n 
A 1 336 ARG 336 215  215 ARG ARG R . n 
A 1 337 LEU 337 216  216 LEU LEU R . n 
A 1 338 HIS 338 217  217 HIS HIS R . n 
A 1 339 VAL 339 218  218 VAL VAL R . n 
A 1 340 LYS 340 219  219 LYS LYS R . n 
A 1 341 ARG 341 220  220 ARG ARG R . n 
A 1 342 ILE 342 221  221 ILE ILE R . n 
A 1 343 ALA 343 222  222 ALA ALA R . n 
A 1 344 ALA 344 223  223 ALA ALA R . n 
A 1 345 LEU 345 224  224 LEU LEU R . n 
A 1 346 PRO 346 225  ?   ?   ?   R . n 
A 1 347 PRO 347 226  ?   ?   ?   R . n 
A 1 348 ALA 348 227  ?   ?   ?   R . n 
A 1 349 ASP 349 228  ?   ?   ?   R . n 
A 1 350 GLY 350 229  ?   ?   ?   R . n 
A 1 351 VAL 351 230  ?   ?   ?   R . n 
A 1 352 ALA 352 231  ?   ?   ?   R . n 
A 1 353 PRO 353 232  ?   ?   ?   R . n 
A 1 354 GLN 354 233  ?   ?   ?   R . n 
A 1 355 GLN 355 234  ?   ?   ?   R . n 
A 1 356 HIS 356 235  ?   ?   ?   R . n 
A 1 357 SER 357 236  ?   ?   ?   R . n 
A 1 358 CYS 358 237  ?   ?   ?   R . n 
A 1 359 MET 359 238  238 MET MET R . n 
A 1 360 LYS 360 239  239 LYS LYS R . n 
A 1 361 GLY 361 240  240 GLY GLY R . n 
A 1 362 ALA 362 241  241 ALA ALA R . n 
A 1 363 VAL 363 242  242 VAL VAL R . n 
A 1 364 THR 364 243  243 THR THR R . n 
A 1 365 ILE 365 244  244 ILE ILE R . n 
A 1 366 THR 366 245  245 THR THR R . n 
A 1 367 ILE 367 246  246 ILE ILE R . n 
A 1 368 LEU 368 247  247 LEU LEU R . n 
A 1 369 LEU 369 248  248 LEU LEU R . n 
A 1 370 GLY 370 249  249 GLY GLY R . n 
A 1 371 VAL 371 250  250 VAL VAL R . n 
A 1 372 PHE 372 251  251 PHE PHE R . n 
A 1 373 ILE 373 252  252 ILE ILE R . n 
A 1 374 PHE 374 253  253 PHE PHE R . n 
A 1 375 CYS 375 254  254 CYS CYS R . n 
A 1 376 TRP 376 255  255 TRP TRP R . n 
A 1 377 ALA 377 256  256 ALA ALA R . n 
A 1 378 PRO 378 257  257 PRO PRO R . n 
A 1 379 PHE 379 258  258 PHE PHE R . n 
A 1 380 PHE 380 259  259 PHE PHE R . n 
A 1 381 LEU 381 260  260 LEU LEU R . n 
A 1 382 HIS 382 261  261 HIS HIS R . n 
A 1 383 LEU 383 262  262 LEU LEU R . n 
A 1 384 VAL 384 263  263 VAL VAL R . n 
A 1 385 LEU 385 264  264 LEU LEU R . n 
A 1 386 ILE 386 265  265 ILE ILE R . n 
A 1 387 ILE 387 266  266 ILE ILE R . n 
A 1 388 THR 388 267  267 THR THR R . n 
A 1 389 CYS 389 268  268 CYS CYS R . n 
A 1 390 PRO 390 269  269 PRO PRO R . n 
A 1 391 THR 391 270  270 THR THR R . n 
A 1 392 ASN 392 271  271 ASN ASN R . n 
A 1 393 PRO 393 272  272 PRO PRO R . n 
A 1 394 TYR 394 273  273 TYR TYR R . n 
A 1 395 CYS 395 274  274 CYS CYS R . n 
A 1 396 ILE 396 275  275 ILE ILE R . n 
A 1 397 CYS 397 276  276 CYS CYS R . n 
A 1 398 TYR 398 277  277 TYR TYR R . n 
A 1 399 THR 399 278  278 THR THR R . n 
A 1 400 ALA 400 279  279 ALA ALA R . n 
A 1 401 HIS 401 280  280 HIS HIS R . n 
A 1 402 PHE 402 281  281 PHE PHE R . n 
A 1 403 ASN 403 282  282 ASN ASN R . n 
A 1 404 THR 404 283  283 THR THR R . n 
A 1 405 TYR 405 284  284 TYR TYR R . n 
A 1 406 LEU 406 285  285 LEU LEU R . n 
A 1 407 VAL 407 286  286 VAL VAL R . n 
A 1 408 LEU 408 287  287 LEU LEU R . n 
A 1 409 ILE 409 288  288 ILE ILE R . n 
A 1 410 MET 410 289  289 MET MET R . n 
A 1 411 CYS 411 290  290 CYS CYS R . n 
A 1 412 ASN 412 291  291 ASN ASN R . n 
A 1 413 SER 413 292  292 SER SER R . n 
A 1 414 VAL 414 293  293 VAL VAL R . n 
A 1 415 ILE 415 294  294 ILE ILE R . n 
A 1 416 ASP 416 295  295 ASP ASP R . n 
A 1 417 PRO 417 296  296 PRO PRO R . n 
A 1 418 LEU 418 297  297 LEU LEU R . n 
A 1 419 ILE 419 298  298 ILE ILE R . n 
A 1 420 TYR 420 299  299 TYR TYR R . n 
A 1 421 ALA 421 300  300 ALA ALA R . n 
A 1 422 PHE 422 301  301 PHE PHE R . n 
A 1 423 ARG 423 302  302 ARG ARG R . n 
A 1 424 SER 424 303  303 SER SER R . n 
A 1 425 LEU 425 304  304 LEU LEU R . n 
A 1 426 GLU 426 305  305 GLU GLU R . n 
A 1 427 LEU 427 306  306 LEU LEU R . n 
A 1 428 ARG 428 307  307 ARG ARG R . n 
A 1 429 ASN 429 308  308 ASN ASN R . n 
A 1 430 THR 430 309  309 THR THR R . n 
A 1 431 PHE 431 310  310 PHE PHE R . n 
A 1 432 ARG 432 311  ?   ?   ?   R . n 
A 1 433 GLU 433 312  ?   ?   ?   R . n 
A 1 434 ILE 434 313  ?   ?   ?   R . n 
A 1 435 LEU 435 314  ?   ?   ?   R . n 
A 1 436 CYS 436 315  ?   ?   ?   R . n 
A 1 437 GLY 437 316  ?   ?   ?   R . n 
A 1 438 CYS 438 317  ?   ?   ?   R . n 
A 1 439 ASN 439 318  ?   ?   ?   R . n 
A 1 440 GLY 440 319  ?   ?   ?   R . n 
A 1 441 MET 441 320  ?   ?   ?   R . n 
A 1 442 ASN 442 321  ?   ?   ?   R . n 
A 1 443 LEU 443 322  ?   ?   ?   R . n 
A 1 444 GLY 444 323  ?   ?   ?   R . n 
A 1 445 VAL 445 324  ?   ?   ?   R . n 
A 1 446 PHE 446 325  ?   ?   ?   R . n 
A 1 447 THR 447 326  ?   ?   ?   R . n 
A 1 448 LEU 448 327  ?   ?   ?   R . n 
A 1 449 GLU 449 328  ?   ?   ?   R . n 
A 1 450 ASP 450 329  ?   ?   ?   R . n 
A 1 451 PHE 451 330  ?   ?   ?   R . n 
A 1 452 VAL 452 331  ?   ?   ?   R . n 
A 1 453 GLY 453 332  ?   ?   ?   R . n 
A 1 454 ASP 454 333  ?   ?   ?   R . n 
A 1 455 TRP 455 334  ?   ?   ?   R . n 
A 1 456 GLU 456 335  ?   ?   ?   R . n 
A 1 457 GLN 457 336  ?   ?   ?   R . n 
A 1 458 THR 458 337  ?   ?   ?   R . n 
A 1 459 ALA 459 338  ?   ?   ?   R . n 
A 1 460 ALA 460 339  ?   ?   ?   R . n 
A 1 461 TYR 461 340  ?   ?   ?   R . n 
A 1 462 ASN 462 341  ?   ?   ?   R . n 
A 1 463 LEU 463 342  ?   ?   ?   R . n 
A 1 464 ASP 464 343  ?   ?   ?   R . n 
A 1 465 GLN 465 344  ?   ?   ?   R . n 
A 1 466 VAL 466 345  ?   ?   ?   R . n 
A 1 467 LEU 467 346  ?   ?   ?   R . n 
A 1 468 GLU 468 347  ?   ?   ?   R . n 
A 1 469 GLN 469 348  ?   ?   ?   R . n 
A 1 470 GLY 470 349  ?   ?   ?   R . n 
A 1 471 GLY 471 350  ?   ?   ?   R . n 
A 1 472 VAL 472 351  ?   ?   ?   R . n 
A 1 473 SER 473 352  ?   ?   ?   R . n 
A 1 474 SER 474 353  ?   ?   ?   R . n 
A 1 475 LEU 475 354  ?   ?   ?   R . n 
A 1 476 LEU 476 355  ?   ?   ?   R . n 
A 1 477 GLN 477 356  ?   ?   ?   R . n 
A 1 478 ASN 478 357  ?   ?   ?   R . n 
A 1 479 LEU 479 358  ?   ?   ?   R . n 
A 1 480 ALA 480 359  ?   ?   ?   R . n 
A 1 481 VAL 481 360  ?   ?   ?   R . n 
A 1 482 SER 482 361  ?   ?   ?   R . n 
A 1 483 VAL 483 362  ?   ?   ?   R . n 
A 1 484 THR 484 363  ?   ?   ?   R . n 
A 1 485 PRO 485 364  ?   ?   ?   R . n 
A 1 486 ILE 486 365  ?   ?   ?   R . n 
A 1 487 GLN 487 366  ?   ?   ?   R . n 
A 1 488 ARG 488 367  ?   ?   ?   R . n 
A 1 489 ILE 489 368  ?   ?   ?   R . n 
A 1 490 VAL 490 369  ?   ?   ?   R . n 
A 1 491 ARG 491 370  ?   ?   ?   R . n 
A 1 492 SER 492 371  ?   ?   ?   R . n 
A 1 493 GLY 493 372  ?   ?   ?   R . n 
A 1 494 GLU 494 373  ?   ?   ?   R . n 
A 1 495 ASN 495 374  ?   ?   ?   R . n 
A 1 496 ALA 496 375  ?   ?   ?   R . n 
A 1 497 LEU 497 376  ?   ?   ?   R . n 
A 1 498 LYS 498 377  ?   ?   ?   R . n 
A 1 499 ILE 499 378  ?   ?   ?   R . n 
A 1 500 ASP 500 379  ?   ?   ?   R . n 
A 1 501 ILE 501 380  ?   ?   ?   R . n 
A 1 502 HIS 502 381  ?   ?   ?   R . n 
A 1 503 VAL 503 382  ?   ?   ?   R . n 
A 1 504 ILE 504 383  ?   ?   ?   R . n 
A 1 505 ILE 505 384  ?   ?   ?   R . n 
A 1 506 PRO 506 385  ?   ?   ?   R . n 
A 1 507 TYR 507 386  ?   ?   ?   R . n 
A 1 508 GLU 508 387  ?   ?   ?   R . n 
A 1 509 GLY 509 388  ?   ?   ?   R . n 
A 1 510 LEU 510 389  ?   ?   ?   R . n 
A 1 511 SER 511 390  ?   ?   ?   R . n 
A 1 512 ALA 512 391  ?   ?   ?   R . n 
A 1 513 ASP 513 392  ?   ?   ?   R . n 
A 1 514 GLN 514 393  ?   ?   ?   R . n 
A 1 515 MET 515 394  ?   ?   ?   R . n 
A 1 516 ALA 516 395  ?   ?   ?   R . n 
A 1 517 GLN 517 396  ?   ?   ?   R . n 
A 1 518 ILE 518 397  ?   ?   ?   R . n 
A 1 519 GLU 519 398  ?   ?   ?   R . n 
A 1 520 GLU 520 399  ?   ?   ?   R . n 
A 1 521 VAL 521 400  ?   ?   ?   R . n 
A 1 522 PHE 522 401  ?   ?   ?   R . n 
A 1 523 LYS 523 402  ?   ?   ?   R . n 
A 1 524 VAL 524 403  ?   ?   ?   R . n 
A 1 525 VAL 525 404  ?   ?   ?   R . n 
A 1 526 TYR 526 405  ?   ?   ?   R . n 
A 1 527 PRO 527 406  ?   ?   ?   R . n 
A 1 528 VAL 528 407  ?   ?   ?   R . n 
A 1 529 ASP 529 408  ?   ?   ?   R . n 
A 1 530 ASP 530 409  ?   ?   ?   R . n 
A 1 531 HIS 531 410  ?   ?   ?   R . n 
A 1 532 HIS 532 411  ?   ?   ?   R . n 
A 1 533 PHE 533 412  ?   ?   ?   R . n 
A 1 534 LYS 534 413  ?   ?   ?   R . n 
A 1 535 VAL 535 414  ?   ?   ?   R . n 
A 1 536 ILE 536 415  ?   ?   ?   R . n 
A 1 537 LEU 537 416  ?   ?   ?   R . n 
A 1 538 PRO 538 417  ?   ?   ?   R . n 
A 1 539 TYR 539 418  ?   ?   ?   R . n 
A 1 540 GLY 540 419  ?   ?   ?   R . n 
A 1 541 THR 541 420  ?   ?   ?   R . n 
A 1 542 LEU 542 421  ?   ?   ?   R . n 
A 1 543 VAL 543 422  ?   ?   ?   R . n 
A 1 544 ILE 544 423  ?   ?   ?   R . n 
A 1 545 ASP 545 424  ?   ?   ?   R . n 
A 1 546 GLY 546 425  ?   ?   ?   R . n 
A 1 547 VAL 547 426  ?   ?   ?   R . n 
A 1 548 THR 548 427  ?   ?   ?   R . n 
A 1 549 PRO 549 428  ?   ?   ?   R . n 
A 1 550 ASN 550 429  ?   ?   ?   R . n 
A 1 551 MET 551 430  ?   ?   ?   R . n 
A 1 552 LEU 552 431  ?   ?   ?   R . n 
A 1 553 ASN 553 432  ?   ?   ?   R . n 
A 1 554 TYR 554 433  ?   ?   ?   R . n 
A 1 555 PHE 555 434  ?   ?   ?   R . n 
A 1 556 GLY 556 435  ?   ?   ?   R . n 
A 1 557 ARG 557 436  ?   ?   ?   R . n 
A 1 558 PRO 558 437  ?   ?   ?   R . n 
A 1 559 TYR 559 438  ?   ?   ?   R . n 
A 1 560 GLU 560 439  ?   ?   ?   R . n 
A 1 561 GLY 561 440  ?   ?   ?   R . n 
A 1 562 ILE 562 441  ?   ?   ?   R . n 
A 1 563 ALA 563 442  ?   ?   ?   R . n 
A 1 564 VAL 564 443  ?   ?   ?   R . n 
A 1 565 PHE 565 444  ?   ?   ?   R . n 
A 1 566 ASP 566 445  ?   ?   ?   R . n 
A 1 567 GLY 567 446  ?   ?   ?   R . n 
A 1 568 LYS 568 447  ?   ?   ?   R . n 
A 1 569 LYS 569 448  ?   ?   ?   R . n 
A 1 570 ILE 570 449  ?   ?   ?   R . n 
A 1 571 THR 571 450  ?   ?   ?   R . n 
A 1 572 VAL 572 451  ?   ?   ?   R . n 
A 1 573 THR 573 452  ?   ?   ?   R . n 
A 1 574 GLY 574 453  ?   ?   ?   R . n 
A 1 575 THR 575 454  ?   ?   ?   R . n 
A 1 576 LEU 576 455  ?   ?   ?   R . n 
A 1 577 TRP 577 456  ?   ?   ?   R . n 
A 1 578 ASN 578 457  ?   ?   ?   R . n 
A 1 579 GLY 579 458  ?   ?   ?   R . n 
A 1 580 ASN 580 459  ?   ?   ?   R . n 
A 1 581 LYS 581 460  ?   ?   ?   R . n 
A 1 582 ILE 582 461  ?   ?   ?   R . n 
A 1 583 ILE 583 462  ?   ?   ?   R . n 
A 1 584 ASP 584 463  ?   ?   ?   R . n 
A 1 585 GLU 585 464  ?   ?   ?   R . n 
A 1 586 ARG 586 465  ?   ?   ?   R . n 
A 1 587 LEU 587 466  ?   ?   ?   R . n 
A 1 588 ILE 588 467  ?   ?   ?   R . n 
A 1 589 THR 589 468  ?   ?   ?   R . n 
A 1 590 PRO 590 469  ?   ?   ?   R . n 
A 1 591 ASP 591 470  ?   ?   ?   R . n 
A 1 592 GLY 592 471  ?   ?   ?   R . n 
A 1 593 SER 593 472  ?   ?   ?   R . n 
A 1 594 MET 594 473  ?   ?   ?   R . n 
A 1 595 LEU 595 474  ?   ?   ?   R . n 
A 1 596 PHE 596 475  ?   ?   ?   R . n 
A 1 597 ARG 597 476  ?   ?   ?   R . n 
A 1 598 VAL 598 477  ?   ?   ?   R . n 
A 1 599 THR 599 478  ?   ?   ?   R . n 
A 1 600 ILE 600 479  ?   ?   ?   R . n 
A 1 601 ASN 601 480  ?   ?   ?   R . n 
A 1 602 SER 602 481  ?   ?   ?   R . n 
B 2 1   MET 1   -17  ?   ?   ?   B . n 
B 2 2   HIS 2   -16  ?   ?   ?   B . n 
B 2 3   HIS 3   -15  ?   ?   ?   B . n 
B 2 4   HIS 4   -14  ?   ?   ?   B . n 
B 2 5   HIS 5   -13  ?   ?   ?   B . n 
B 2 6   HIS 6   -12  ?   ?   ?   B . n 
B 2 7   HIS 7   -11  ?   ?   ?   B . n 
B 2 8   LEU 8   -10  ?   ?   ?   B . n 
B 2 9   GLU 9   -9   ?   ?   ?   B . n 
B 2 10  VAL 10  -8   ?   ?   ?   B . n 
B 2 11  LEU 11  -7   ?   ?   ?   B . n 
B 2 12  PHE 12  -6   ?   ?   ?   B . n 
B 2 13  GLN 13  -5   ?   ?   ?   B . n 
B 2 14  GLY 14  -4   ?   ?   ?   B . n 
B 2 15  PRO 15  -3   ?   ?   ?   B . n 
B 2 16  GLY 16  -2   ?   ?   ?   B . n 
B 2 17  SER 17  -1   ?   ?   ?   B . n 
B 2 18  SER 18  0    ?   ?   ?   B . n 
B 2 19  GLY 19  1    ?   ?   ?   B . n 
B 2 20  SER 20  2    ?   ?   ?   B . n 
B 2 21  GLU 21  3    3   GLU GLU B . n 
B 2 22  LEU 22  4    4   LEU LEU B . n 
B 2 23  ASP 23  5    5   ASP ASP B . n 
B 2 24  GLN 24  6    6   GLN GLN B . n 
B 2 25  LEU 25  7    7   LEU LEU B . n 
B 2 26  ARG 26  8    8   ARG ARG B . n 
B 2 27  GLN 27  9    9   GLN GLN B . n 
B 2 28  GLU 28  10   10  GLU GLU B . n 
B 2 29  ALA 29  11   11  ALA ALA B . n 
B 2 30  GLU 30  12   12  GLU GLU B . n 
B 2 31  GLN 31  13   13  GLN GLN B . n 
B 2 32  LEU 32  14   14  LEU LEU B . n 
B 2 33  LYS 33  15   15  LYS LYS B . n 
B 2 34  ASN 34  16   16  ASN ASN B . n 
B 2 35  GLN 35  17   17  GLN GLN B . n 
B 2 36  ILE 36  18   18  ILE ILE B . n 
B 2 37  ARG 37  19   19  ARG ARG B . n 
B 2 38  ASP 38  20   20  ASP ASP B . n 
B 2 39  ALA 39  21   21  ALA ALA B . n 
B 2 40  ARG 40  22   22  ARG ARG B . n 
B 2 41  LYS 41  23   23  LYS LYS B . n 
B 2 42  ALA 42  24   24  ALA ALA B . n 
B 2 43  CYS 43  25   25  CYS CYS B . n 
B 2 44  ALA 44  26   26  ALA ALA B . n 
B 2 45  ASP 45  27   27  ASP ASP B . n 
B 2 46  ALA 46  28   28  ALA ALA B . n 
B 2 47  THR 47  29   29  THR THR B . n 
B 2 48  LEU 48  30   30  LEU LEU B . n 
B 2 49  SER 49  31   31  SER SER B . n 
B 2 50  GLN 50  32   32  GLN GLN B . n 
B 2 51  ILE 51  33   33  ILE ILE B . n 
B 2 52  THR 52  34   34  THR THR B . n 
B 2 53  ASN 53  35   35  ASN ASN B . n 
B 2 54  ASN 54  36   36  ASN ASN B . n 
B 2 55  ILE 55  37   37  ILE ILE B . n 
B 2 56  ASP 56  38   38  ASP ASP B . n 
B 2 57  PRO 57  39   39  PRO PRO B . n 
B 2 58  VAL 58  40   40  VAL VAL B . n 
B 2 59  GLY 59  41   41  GLY GLY B . n 
B 2 60  ARG 60  42   42  ARG ARG B . n 
B 2 61  ILE 61  43   43  ILE ILE B . n 
B 2 62  GLN 62  44   44  GLN GLN B . n 
B 2 63  MET 63  45   45  MET MET B . n 
B 2 64  ARG 64  46   46  ARG ARG B . n 
B 2 65  THR 65  47   47  THR THR B . n 
B 2 66  ARG 66  48   48  ARG ARG B . n 
B 2 67  ARG 67  49   49  ARG ARG B . n 
B 2 68  THR 68  50   50  THR THR B . n 
B 2 69  LEU 69  51   51  LEU LEU B . n 
B 2 70  ARG 70  52   52  ARG ARG B . n 
B 2 71  GLY 71  53   53  GLY GLY B . n 
B 2 72  HIS 72  54   54  HIS HIS B . n 
B 2 73  LEU 73  55   55  LEU LEU B . n 
B 2 74  ALA 74  56   56  ALA ALA B . n 
B 2 75  LYS 75  57   57  LYS LYS B . n 
B 2 76  ILE 76  58   58  ILE ILE B . n 
B 2 77  TYR 77  59   59  TYR TYR B . n 
B 2 78  ALA 78  60   60  ALA ALA B . n 
B 2 79  MET 79  61   61  MET MET B . n 
B 2 80  HIS 80  62   62  HIS HIS B . n 
B 2 81  TRP 81  63   63  TRP TRP B . n 
B 2 82  GLY 82  64   64  GLY GLY B . n 
B 2 83  THR 83  65   65  THR THR B . n 
B 2 84  ASP 84  66   66  ASP ASP B . n 
B 2 85  SER 85  67   67  SER SER B . n 
B 2 86  ARG 86  68   68  ARG ARG B . n 
B 2 87  LEU 87  69   69  LEU LEU B . n 
B 2 88  LEU 88  70   70  LEU LEU B . n 
B 2 89  VAL 89  71   71  VAL VAL B . n 
B 2 90  SER 90  72   72  SER SER B . n 
B 2 91  ALA 91  73   73  ALA ALA B . n 
B 2 92  SER 92  74   74  SER SER B . n 
B 2 93  GLN 93  75   75  GLN GLN B . n 
B 2 94  ASP 94  76   76  ASP ASP B . n 
B 2 95  GLY 95  77   77  GLY GLY B . n 
B 2 96  LYS 96  78   78  LYS LYS B . n 
B 2 97  LEU 97  79   79  LEU LEU B . n 
B 2 98  ILE 98  80   80  ILE ILE B . n 
B 2 99  ILE 99  81   81  ILE ILE B . n 
B 2 100 TRP 100 82   82  TRP TRP B . n 
B 2 101 ASP 101 83   83  ASP ASP B . n 
B 2 102 SER 102 84   84  SER SER B . n 
B 2 103 TYR 103 85   85  TYR TYR B . n 
B 2 104 THR 104 86   86  THR THR B . n 
B 2 105 THR 105 87   87  THR THR B . n 
B 2 106 ASN 106 88   88  ASN ASN B . n 
B 2 107 LYS 107 89   89  LYS LYS B . n 
B 2 108 VAL 108 90   90  VAL VAL B . n 
B 2 109 HIS 109 91   91  HIS HIS B . n 
B 2 110 ALA 110 92   92  ALA ALA B . n 
B 2 111 ILE 111 93   93  ILE ILE B . n 
B 2 112 PRO 112 94   94  PRO PRO B . n 
B 2 113 LEU 113 95   95  LEU LEU B . n 
B 2 114 ARG 114 96   96  ARG ARG B . n 
B 2 115 SER 115 97   97  SER SER B . n 
B 2 116 SER 116 98   98  SER SER B . n 
B 2 117 TRP 117 99   99  TRP TRP B . n 
B 2 118 VAL 118 100  100 VAL VAL B . n 
B 2 119 MET 119 101  101 MET MET B . n 
B 2 120 THR 120 102  102 THR THR B . n 
B 2 121 CYS 121 103  103 CYS CYS B . n 
B 2 122 ALA 122 104  104 ALA ALA B . n 
B 2 123 TYR 123 105  105 TYR TYR B . n 
B 2 124 ALA 124 106  106 ALA ALA B . n 
B 2 125 PRO 125 107  107 PRO PRO B . n 
B 2 126 SER 126 108  108 SER SER B . n 
B 2 127 GLY 127 109  109 GLY GLY B . n 
B 2 128 ASN 128 110  110 ASN ASN B . n 
B 2 129 TYR 129 111  111 TYR TYR B . n 
B 2 130 VAL 130 112  112 VAL VAL B . n 
B 2 131 ALA 131 113  113 ALA ALA B . n 
B 2 132 CYS 132 114  114 CYS CYS B . n 
B 2 133 GLY 133 115  115 GLY GLY B . n 
B 2 134 GLY 134 116  116 GLY GLY B . n 
B 2 135 LEU 135 117  117 LEU LEU B . n 
B 2 136 ASP 136 118  118 ASP ASP B . n 
B 2 137 ASN 137 119  119 ASN ASN B . n 
B 2 138 ILE 138 120  120 ILE ILE B . n 
B 2 139 CYS 139 121  121 CYS CYS B . n 
B 2 140 SER 140 122  122 SER SER B . n 
B 2 141 ILE 141 123  123 ILE ILE B . n 
B 2 142 TYR 142 124  124 TYR TYR B . n 
B 2 143 ASN 143 125  125 ASN ASN B . n 
B 2 144 LEU 144 126  126 LEU LEU B . n 
B 2 145 LYS 145 127  127 LYS LYS B . n 
B 2 146 THR 146 128  128 THR THR B . n 
B 2 147 ARG 147 129  129 ARG ARG B . n 
B 2 148 GLU 148 130  130 GLU GLU B . n 
B 2 149 GLY 149 131  131 GLY GLY B . n 
B 2 150 ASN 150 132  132 ASN ASN B . n 
B 2 151 VAL 151 133  133 VAL VAL B . n 
B 2 152 ARG 152 134  134 ARG ARG B . n 
B 2 153 VAL 153 135  135 VAL VAL B . n 
B 2 154 SER 154 136  136 SER SER B . n 
B 2 155 ARG 155 137  137 ARG ARG B . n 
B 2 156 GLU 156 138  138 GLU GLU B . n 
B 2 157 LEU 157 139  139 LEU LEU B . n 
B 2 158 ALA 158 140  140 ALA ALA B . n 
B 2 159 GLY 159 141  141 GLY GLY B . n 
B 2 160 HIS 160 142  142 HIS HIS B . n 
B 2 161 THR 161 143  143 THR THR B . n 
B 2 162 GLY 162 144  144 GLY GLY B . n 
B 2 163 TYR 163 145  145 TYR TYR B . n 
B 2 164 LEU 164 146  146 LEU LEU B . n 
B 2 165 SER 165 147  147 SER SER B . n 
B 2 166 CYS 166 148  148 CYS CYS B . n 
B 2 167 CYS 167 149  149 CYS CYS B . n 
B 2 168 ARG 168 150  150 ARG ARG B . n 
B 2 169 PHE 169 151  151 PHE PHE B . n 
B 2 170 LEU 170 152  152 LEU LEU B . n 
B 2 171 ASP 171 153  153 ASP ASP B . n 
B 2 172 ASP 172 154  154 ASP ASP B . n 
B 2 173 ASN 173 155  155 ASN ASN B . n 
B 2 174 GLN 174 156  156 GLN GLN B . n 
B 2 175 ILE 175 157  157 ILE ILE B . n 
B 2 176 VAL 176 158  158 VAL VAL B . n 
B 2 177 THR 177 159  159 THR THR B . n 
B 2 178 SER 178 160  160 SER SER B . n 
B 2 179 SER 179 161  161 SER SER B . n 
B 2 180 GLY 180 162  162 GLY GLY B . n 
B 2 181 ASP 181 163  163 ASP ASP B . n 
B 2 182 THR 182 164  164 THR THR B . n 
B 2 183 THR 183 165  165 THR THR B . n 
B 2 184 CYS 184 166  166 CYS CYS B . n 
B 2 185 ALA 185 167  167 ALA ALA B . n 
B 2 186 LEU 186 168  168 LEU LEU B . n 
B 2 187 TRP 187 169  169 TRP TRP B . n 
B 2 188 ASP 188 170  170 ASP ASP B . n 
B 2 189 ILE 189 171  171 ILE ILE B . n 
B 2 190 GLU 190 172  172 GLU GLU B . n 
B 2 191 THR 191 173  173 THR THR B . n 
B 2 192 GLY 192 174  174 GLY GLY B . n 
B 2 193 GLN 193 175  175 GLN GLN B . n 
B 2 194 GLN 194 176  176 GLN GLN B . n 
B 2 195 THR 195 177  177 THR THR B . n 
B 2 196 THR 196 178  178 THR THR B . n 
B 2 197 THR 197 179  179 THR THR B . n 
B 2 198 PHE 198 180  180 PHE PHE B . n 
B 2 199 THR 199 181  181 THR THR B . n 
B 2 200 GLY 200 182  182 GLY GLY B . n 
B 2 201 HIS 201 183  183 HIS HIS B . n 
B 2 202 THR 202 184  184 THR THR B . n 
B 2 203 GLY 203 185  185 GLY GLY B . n 
B 2 204 ASP 204 186  186 ASP ASP B . n 
B 2 205 VAL 205 187  187 VAL VAL B . n 
B 2 206 MET 206 188  188 MET MET B . n 
B 2 207 SER 207 189  189 SER SER B . n 
B 2 208 LEU 208 190  190 LEU LEU B . n 
B 2 209 SER 209 191  191 SER SER B . n 
B 2 210 LEU 210 192  192 LEU LEU B . n 
B 2 211 ALA 211 193  193 ALA ALA B . n 
B 2 212 PRO 212 194  194 PRO PRO B . n 
B 2 213 ASP 213 195  195 ASP ASP B . n 
B 2 214 THR 214 196  196 THR THR B . n 
B 2 215 ARG 215 197  197 ARG ARG B . n 
B 2 216 LEU 216 198  198 LEU LEU B . n 
B 2 217 PHE 217 199  199 PHE PHE B . n 
B 2 218 VAL 218 200  200 VAL VAL B . n 
B 2 219 SER 219 201  201 SER SER B . n 
B 2 220 GLY 220 202  202 GLY GLY B . n 
B 2 221 ALA 221 203  203 ALA ALA B . n 
B 2 222 CYS 222 204  204 CYS CYS B . n 
B 2 223 ASP 223 205  205 ASP ASP B . n 
B 2 224 ALA 224 206  206 ALA ALA B . n 
B 2 225 SER 225 207  207 SER SER B . n 
B 2 226 ALA 226 208  208 ALA ALA B . n 
B 2 227 LYS 227 209  209 LYS LYS B . n 
B 2 228 LEU 228 210  210 LEU LEU B . n 
B 2 229 TRP 229 211  211 TRP TRP B . n 
B 2 230 ASP 230 212  212 ASP ASP B . n 
B 2 231 VAL 231 213  213 VAL VAL B . n 
B 2 232 ARG 232 214  214 ARG ARG B . n 
B 2 233 GLU 233 215  215 GLU GLU B . n 
B 2 234 GLY 234 216  216 GLY GLY B . n 
B 2 235 MET 235 217  217 MET MET B . n 
B 2 236 CYS 236 218  218 CYS CYS B . n 
B 2 237 ARG 237 219  219 ARG ARG B . n 
B 2 238 GLN 238 220  220 GLN GLN B . n 
B 2 239 THR 239 221  221 THR THR B . n 
B 2 240 PHE 240 222  222 PHE PHE B . n 
B 2 241 THR 241 223  223 THR THR B . n 
B 2 242 GLY 242 224  224 GLY GLY B . n 
B 2 243 HIS 243 225  225 HIS HIS B . n 
B 2 244 GLU 244 226  226 GLU GLU B . n 
B 2 245 SER 245 227  227 SER SER B . n 
B 2 246 ASP 246 228  228 ASP ASP B . n 
B 2 247 ILE 247 229  229 ILE ILE B . n 
B 2 248 ASN 248 230  230 ASN ASN B . n 
B 2 249 ALA 249 231  231 ALA ALA B . n 
B 2 250 ILE 250 232  232 ILE ILE B . n 
B 2 251 CYS 251 233  233 CYS CYS B . n 
B 2 252 PHE 252 234  234 PHE PHE B . n 
B 2 253 PHE 253 235  235 PHE PHE B . n 
B 2 254 PRO 254 236  236 PRO PRO B . n 
B 2 255 ASN 255 237  237 ASN ASN B . n 
B 2 256 GLY 256 238  238 GLY GLY B . n 
B 2 257 ASN 257 239  239 ASN ASN B . n 
B 2 258 ALA 258 240  240 ALA ALA B . n 
B 2 259 PHE 259 241  241 PHE PHE B . n 
B 2 260 ALA 260 242  242 ALA ALA B . n 
B 2 261 THR 261 243  243 THR THR B . n 
B 2 262 GLY 262 244  244 GLY GLY B . n 
B 2 263 SER 263 245  245 SER SER B . n 
B 2 264 ASP 264 246  246 ASP ASP B . n 
B 2 265 ASP 265 247  247 ASP ASP B . n 
B 2 266 ALA 266 248  248 ALA ALA B . n 
B 2 267 THR 267 249  249 THR THR B . n 
B 2 268 CYS 268 250  250 CYS CYS B . n 
B 2 269 ARG 269 251  251 ARG ARG B . n 
B 2 270 LEU 270 252  252 LEU LEU B . n 
B 2 271 PHE 271 253  253 PHE PHE B . n 
B 2 272 ASP 272 254  254 ASP ASP B . n 
B 2 273 LEU 273 255  255 LEU LEU B . n 
B 2 274 ARG 274 256  256 ARG ARG B . n 
B 2 275 ALA 275 257  257 ALA ALA B . n 
B 2 276 ASP 276 258  258 ASP ASP B . n 
B 2 277 GLN 277 259  259 GLN GLN B . n 
B 2 278 GLU 278 260  260 GLU GLU B . n 
B 2 279 LEU 279 261  261 LEU LEU B . n 
B 2 280 MET 280 262  262 MET MET B . n 
B 2 281 THR 281 263  263 THR THR B . n 
B 2 282 TYR 282 264  264 TYR TYR B . n 
B 2 283 SER 283 265  265 SER SER B . n 
B 2 284 HIS 284 266  266 HIS HIS B . n 
B 2 285 ASP 285 267  267 ASP ASP B . n 
B 2 286 ASN 286 268  268 ASN ASN B . n 
B 2 287 ILE 287 269  269 ILE ILE B . n 
B 2 288 ILE 288 270  270 ILE ILE B . n 
B 2 289 CYS 289 271  271 CYS CYS B . n 
B 2 290 GLY 290 272  272 GLY GLY B . n 
B 2 291 ILE 291 273  273 ILE ILE B . n 
B 2 292 THR 292 274  274 THR THR B . n 
B 2 293 SER 293 275  275 SER SER B . n 
B 2 294 VAL 294 276  276 VAL VAL B . n 
B 2 295 SER 295 277  277 SER SER B . n 
B 2 296 PHE 296 278  278 PHE PHE B . n 
B 2 297 SER 297 279  279 SER SER B . n 
B 2 298 LYS 298 280  280 LYS LYS B . n 
B 2 299 SER 299 281  281 SER SER B . n 
B 2 300 GLY 300 282  282 GLY GLY B . n 
B 2 301 ARG 301 283  283 ARG ARG B . n 
B 2 302 LEU 302 284  284 LEU LEU B . n 
B 2 303 LEU 303 285  285 LEU LEU B . n 
B 2 304 LEU 304 286  286 LEU LEU B . n 
B 2 305 ALA 305 287  287 ALA ALA B . n 
B 2 306 GLY 306 288  288 GLY GLY B . n 
B 2 307 TYR 307 289  289 TYR TYR B . n 
B 2 308 ASP 308 290  290 ASP ASP B . n 
B 2 309 ASP 309 291  291 ASP ASP B . n 
B 2 310 PHE 310 292  292 PHE PHE B . n 
B 2 311 ASN 311 293  293 ASN ASN B . n 
B 2 312 CYS 312 294  294 CYS CYS B . n 
B 2 313 ASN 313 295  295 ASN ASN B . n 
B 2 314 VAL 314 296  296 VAL VAL B . n 
B 2 315 TRP 315 297  297 TRP TRP B . n 
B 2 316 ASP 316 298  298 ASP ASP B . n 
B 2 317 ALA 317 299  299 ALA ALA B . n 
B 2 318 LEU 318 300  300 LEU LEU B . n 
B 2 319 LYS 319 301  301 LYS LYS B . n 
B 2 320 ALA 320 302  302 ALA ALA B . n 
B 2 321 ASP 321 303  303 ASP ASP B . n 
B 2 322 ARG 322 304  304 ARG ARG B . n 
B 2 323 ALA 323 305  305 ALA ALA B . n 
B 2 324 GLY 324 306  306 GLY GLY B . n 
B 2 325 VAL 325 307  307 VAL VAL B . n 
B 2 326 LEU 326 308  308 LEU LEU B . n 
B 2 327 ALA 327 309  309 ALA ALA B . n 
B 2 328 GLY 328 310  310 GLY GLY B . n 
B 2 329 HIS 329 311  311 HIS HIS B . n 
B 2 330 ASP 330 312  312 ASP ASP B . n 
B 2 331 ASN 331 313  313 ASN ASN B . n 
B 2 332 ARG 332 314  314 ARG ARG B . n 
B 2 333 VAL 333 315  315 VAL VAL B . n 
B 2 334 SER 334 316  316 SER SER B . n 
B 2 335 CYS 335 317  317 CYS CYS B . n 
B 2 336 LEU 336 318  318 LEU LEU B . n 
B 2 337 GLY 337 319  319 GLY GLY B . n 
B 2 338 VAL 338 320  320 VAL VAL B . n 
B 2 339 THR 339 321  321 THR THR B . n 
B 2 340 ASP 340 322  322 ASP ASP B . n 
B 2 341 ASP 341 323  323 ASP ASP B . n 
B 2 342 GLY 342 324  324 GLY GLY B . n 
B 2 343 MET 343 325  325 MET MET B . n 
B 2 344 ALA 344 326  326 ALA ALA B . n 
B 2 345 VAL 345 327  327 VAL VAL B . n 
B 2 346 ALA 346 328  328 ALA ALA B . n 
B 2 347 THR 347 329  329 THR THR B . n 
B 2 348 GLY 348 330  330 GLY GLY B . n 
B 2 349 SER 349 331  331 SER SER B . n 
B 2 350 TRP 350 332  332 TRP TRP B . n 
B 2 351 ASP 351 333  333 ASP ASP B . n 
B 2 352 SER 352 334  334 SER SER B . n 
B 2 353 PHE 353 335  335 PHE PHE B . n 
B 2 354 LEU 354 336  336 LEU LEU B . n 
B 2 355 LYS 355 337  337 LYS LYS B . n 
B 2 356 ILE 356 338  338 ILE ILE B . n 
B 2 357 TRP 357 339  339 TRP TRP B . n 
B 2 358 ASN 358 340  340 ASN ASN B . n 
B 2 359 GLY 359 341  ?   ?   ?   B . n 
B 2 360 SER 360 342  ?   ?   ?   B . n 
B 2 361 SER 361 343  ?   ?   ?   B . n 
B 2 362 GLY 362 344  ?   ?   ?   B . n 
B 2 363 GLY 363 345  ?   ?   ?   B . n 
B 2 364 GLY 364 346  ?   ?   ?   B . n 
B 2 365 GLY 365 347  ?   ?   ?   B . n 
B 2 366 SER 366 348  ?   ?   ?   B . n 
B 2 367 GLY 367 349  ?   ?   ?   B . n 
B 2 368 GLY 368 350  ?   ?   ?   B . n 
B 2 369 GLY 369 351  ?   ?   ?   B . n 
B 2 370 GLY 370 352  ?   ?   ?   B . n 
B 2 371 SER 371 353  ?   ?   ?   B . n 
B 2 372 SER 372 354  ?   ?   ?   B . n 
B 2 373 GLY 373 355  ?   ?   ?   B . n 
B 2 374 VAL 374 356  ?   ?   ?   B . n 
B 2 375 SER 375 357  ?   ?   ?   B . n 
B 2 376 GLY 376 358  ?   ?   ?   B . n 
B 2 377 TRP 377 359  ?   ?   ?   B . n 
B 2 378 ARG 378 360  ?   ?   ?   B . n 
B 2 379 LEU 379 361  ?   ?   ?   B . n 
B 2 380 PHE 380 362  ?   ?   ?   B . n 
B 2 381 LYS 381 363  ?   ?   ?   B . n 
B 2 382 LYS 382 364  ?   ?   ?   B . n 
B 2 383 ILE 383 365  ?   ?   ?   B . n 
B 2 384 SER 384 366  ?   ?   ?   B . n 
C 3 1   MET 1   1    ?   ?   ?   G . n 
C 3 2   ALA 2   2    ?   ?   ?   G . n 
C 3 3   SER 3   3    ?   ?   ?   G . n 
C 3 4   ASN 4   4    ?   ?   ?   G . n 
C 3 5   ASN 5   5    ?   ?   ?   G . n 
C 3 6   THR 6   6    6   THR THR G . n 
C 3 7   ALA 7   7    7   ALA ALA G . n 
C 3 8   SER 8   8    8   SER SER G . n 
C 3 9   ILE 9   9    9   ILE ILE G . n 
C 3 10  ALA 10  10   10  ALA ALA G . n 
C 3 11  GLN 11  11   11  GLN GLN G . n 
C 3 12  ALA 12  12   12  ALA ALA G . n 
C 3 13  ARG 13  13   13  ARG ARG G . n 
C 3 14  LYS 14  14   14  LYS LYS G . n 
C 3 15  LEU 15  15   15  LEU LEU G . n 
C 3 16  VAL 16  16   16  VAL VAL G . n 
C 3 17  GLU 17  17   17  GLU GLU G . n 
C 3 18  GLN 18  18   18  GLN GLN G . n 
C 3 19  LEU 19  19   19  LEU LEU G . n 
C 3 20  LYS 20  20   20  LYS LYS G . n 
C 3 21  MET 21  21   21  MET MET G . n 
C 3 22  GLU 22  22   22  GLU GLU G . n 
C 3 23  ALA 23  23   23  ALA ALA G . n 
C 3 24  ASN 24  24   24  ASN ASN G . n 
C 3 25  ILE 25  25   25  ILE ILE G . n 
C 3 26  ASP 26  26   26  ASP ASP G . n 
C 3 27  ARG 27  27   27  ARG ARG G . n 
C 3 28  ILE 28  28   28  ILE ILE G . n 
C 3 29  LYS 29  29   29  LYS LYS G . n 
C 3 30  VAL 30  30   30  VAL VAL G . n 
C 3 31  SER 31  31   31  SER SER G . n 
C 3 32  LYS 32  32   32  LYS LYS G . n 
C 3 33  ALA 33  33   33  ALA ALA G . n 
C 3 34  ALA 34  34   34  ALA ALA G . n 
C 3 35  ALA 35  35   35  ALA ALA G . n 
C 3 36  ASP 36  36   36  ASP ASP G . n 
C 3 37  LEU 37  37   37  LEU LEU G . n 
C 3 38  MET 38  38   38  MET MET G . n 
C 3 39  ALA 39  39   39  ALA ALA G . n 
C 3 40  TYR 40  40   40  TYR TYR G . n 
C 3 41  CYS 41  41   41  CYS CYS G . n 
C 3 42  GLU 42  42   42  GLU GLU G . n 
C 3 43  ALA 43  43   43  ALA ALA G . n 
C 3 44  HIS 44  44   44  HIS HIS G . n 
C 3 45  ALA 45  45   45  ALA ALA G . n 
C 3 46  LYS 46  46   46  LYS LYS G . n 
C 3 47  GLU 47  47   47  GLU GLU G . n 
C 3 48  ASP 48  48   48  ASP ASP G . n 
C 3 49  PRO 49  49   49  PRO PRO G . n 
C 3 50  LEU 50  50   50  LEU LEU G . n 
C 3 51  LEU 51  51   51  LEU LEU G . n 
C 3 52  THR 52  52   52  THR THR G . n 
C 3 53  PRO 53  53   53  PRO PRO G . n 
C 3 54  VAL 54  54   54  VAL VAL G . n 
C 3 55  PRO 55  55   55  PRO PRO G . n 
C 3 56  ALA 56  56   56  ALA ALA G . n 
C 3 57  SER 57  57   57  SER SER G . n 
C 3 58  GLU 58  58   58  GLU GLU G . n 
C 3 59  ASN 59  59   59  ASN ASN G . n 
C 3 60  PRO 60  60   60  PRO PRO G . n 
C 3 61  PHE 61  61   61  PHE PHE G . n 
C 3 62  ARG 62  62   62  ARG ARG G . n 
C 3 63  GLU 63  63   ?   ?   ?   G . n 
C 3 64  LYS 64  64   ?   ?   ?   G . n 
C 3 65  LYS 65  65   ?   ?   ?   G . n 
C 3 66  PHE 66  66   ?   ?   ?   G . n 
C 3 67  PHE 67  67   ?   ?   ?   G . n 
C 3 68  CYS 68  68   ?   ?   ?   G . n 
C 3 69  ALA 69  69   ?   ?   ?   G . n 
C 3 70  ILE 70  70   ?   ?   ?   G . n 
C 3 71  LEU 71  71   ?   ?   ?   G . n 
D 4 1   MET 1   -21  ?   ?   ?   N . n 
D 4 2   LYS 2   -20  ?   ?   ?   N . n 
D 4 3   TYR 3   -19  ?   ?   ?   N . n 
D 4 4   LEU 4   -18  ?   ?   ?   N . n 
D 4 5   LEU 5   -17  ?   ?   ?   N . n 
D 4 6   PRO 6   -16  ?   ?   ?   N . n 
D 4 7   THR 7   -15  ?   ?   ?   N . n 
D 4 8   ALA 8   -14  ?   ?   ?   N . n 
D 4 9   ALA 9   -13  ?   ?   ?   N . n 
D 4 10  ALA 10  -12  ?   ?   ?   N . n 
D 4 11  GLY 11  -11  ?   ?   ?   N . n 
D 4 12  LEU 12  -10  ?   ?   ?   N . n 
D 4 13  LEU 13  -9   ?   ?   ?   N . n 
D 4 14  LEU 14  -8   ?   ?   ?   N . n 
D 4 15  LEU 15  -7   ?   ?   ?   N . n 
D 4 16  ALA 16  -6   ?   ?   ?   N . n 
D 4 17  ALA 17  -5   ?   ?   ?   N . n 
D 4 18  GLN 18  -4   ?   ?   ?   N . n 
D 4 19  PRO 19  -3   ?   ?   ?   N . n 
D 4 20  ALA 20  -2   ?   ?   ?   N . n 
D 4 21  MET 21  -1   ?   ?   ?   N . n 
D 4 22  ALA 22  0    ?   ?   ?   N . n 
D 4 23  GLN 23  1    1   GLN GLN N . n 
D 4 24  VAL 24  2    2   VAL VAL N . n 
D 4 25  GLN 25  3    3   GLN GLN N . n 
D 4 26  LEU 26  4    4   LEU LEU N . n 
D 4 27  GLN 27  5    5   GLN GLN N . n 
D 4 28  GLU 28  6    6   GLU GLU N . n 
D 4 29  SER 29  7    7   SER SER N . n 
D 4 30  GLY 30  8    8   GLY GLY N . n 
D 4 31  GLY 31  9    9   GLY GLY N . n 
D 4 32  GLY 32  10   10  GLY GLY N . n 
D 4 33  LEU 33  11   11  LEU LEU N . n 
D 4 34  VAL 34  12   12  VAL VAL N . n 
D 4 35  GLN 35  13   13  GLN GLN N . n 
D 4 36  PRO 36  14   14  PRO PRO N . n 
D 4 37  GLY 37  15   15  GLY GLY N . n 
D 4 38  GLY 38  16   16  GLY GLY N . n 
D 4 39  SER 39  17   17  SER SER N . n 
D 4 40  LEU 40  18   18  LEU LEU N . n 
D 4 41  ARG 41  19   19  ARG ARG N . n 
D 4 42  LEU 42  20   20  LEU LEU N . n 
D 4 43  SER 43  21   21  SER SER N . n 
D 4 44  CYS 44  22   22  CYS CYS N . n 
D 4 45  ALA 45  23   23  ALA ALA N . n 
D 4 46  ALA 46  24   24  ALA ALA N . n 
D 4 47  SER 47  25   25  SER SER N . n 
D 4 48  GLY 48  26   26  GLY GLY N . n 
D 4 49  PHE 49  27   27  PHE PHE N . n 
D 4 50  THR 50  28   28  THR THR N . n 
D 4 51  PHE 51  29   29  PHE PHE N . n 
D 4 52  SER 52  30   30  SER SER N . n 
D 4 53  ASN 53  31   31  ASN ASN N . n 
D 4 54  TYR 54  32   32  TYR TYR N . n 
D 4 55  LYS 55  33   33  LYS LYS N . n 
D 4 56  MET 56  34   34  MET MET N . n 
D 4 57  ASN 57  35   35  ASN ASN N . n 
D 4 58  TRP 58  36   36  TRP TRP N . n 
D 4 59  VAL 59  37   37  VAL VAL N . n 
D 4 60  ARG 60  38   38  ARG ARG N . n 
D 4 61  GLN 61  39   39  GLN GLN N . n 
D 4 62  ALA 62  40   40  ALA ALA N . n 
D 4 63  PRO 63  41   41  PRO PRO N . n 
D 4 64  GLY 64  42   42  GLY GLY N . n 
D 4 65  LYS 65  43   43  LYS LYS N . n 
D 4 66  GLY 66  44   44  GLY GLY N . n 
D 4 67  LEU 67  45   45  LEU LEU N . n 
D 4 68  GLU 68  46   46  GLU GLU N . n 
D 4 69  TRP 69  47   47  TRP TRP N . n 
D 4 70  VAL 70  48   48  VAL VAL N . n 
D 4 71  SER 71  49   49  SER SER N . n 
D 4 72  ASP 72  50   50  ASP ASP N . n 
D 4 73  ILE 73  51   51  ILE ILE N . n 
D 4 74  SER 74  52   52  SER SER N . n 
D 4 75  GLN 75  53   53  GLN GLN N . n 
D 4 76  SER 76  54   54  SER SER N . n 
D 4 77  GLY 77  55   55  GLY GLY N . n 
D 4 78  ALA 78  56   56  ALA ALA N . n 
D 4 79  SER 79  57   57  SER SER N . n 
D 4 80  ILE 80  58   58  ILE ILE N . n 
D 4 81  SER 81  59   59  SER SER N . n 
D 4 82  TYR 82  60   60  TYR TYR N . n 
D 4 83  THR 83  61   61  THR THR N . n 
D 4 84  GLY 84  62   62  GLY GLY N . n 
D 4 85  SER 85  63   63  SER SER N . n 
D 4 86  VAL 86  64   64  VAL VAL N . n 
D 4 87  LYS 87  65   65  LYS LYS N . n 
D 4 88  GLY 88  66   66  GLY GLY N . n 
D 4 89  ARG 89  67   67  ARG ARG N . n 
D 4 90  PHE 90  68   68  PHE PHE N . n 
D 4 91  THR 91  69   69  THR THR N . n 
D 4 92  ILE 92  70   70  ILE ILE N . n 
D 4 93  SER 93  71   71  SER SER N . n 
D 4 94  ARG 94  72   72  ARG ARG N . n 
D 4 95  ASP 95  73   73  ASP ASP N . n 
D 4 96  ASN 96  74   74  ASN ASN N . n 
D 4 97  ALA 97  75   75  ALA ALA N . n 
D 4 98  LYS 98  76   76  LYS LYS N . n 
D 4 99  ASN 99  77   77  ASN ASN N . n 
D 4 100 THR 100 78   78  THR THR N . n 
D 4 101 LEU 101 79   79  LEU LEU N . n 
D 4 102 TYR 102 80   80  TYR TYR N . n 
D 4 103 LEU 103 81   81  LEU LEU N . n 
D 4 104 GLN 104 82   82  GLN GLN N . n 
D 4 105 MET 105 83   83  MET MET N . n 
D 4 106 ASN 106 84   84  ASN ASN N . n 
D 4 107 SER 107 85   85  SER SER N . n 
D 4 108 LEU 108 86   86  LEU LEU N . n 
D 4 109 LYS 109 87   87  LYS LYS N . n 
D 4 110 PRO 110 88   88  PRO PRO N . n 
D 4 111 GLU 111 89   89  GLU GLU N . n 
D 4 112 ASP 112 90   90  ASP ASP N . n 
D 4 113 THR 113 91   91  THR THR N . n 
D 4 114 ALA 114 92   92  ALA ALA N . n 
D 4 115 VAL 115 93   93  VAL VAL N . n 
D 4 116 TYR 116 94   94  TYR TYR N . n 
D 4 117 TYR 117 95   95  TYR TYR N . n 
D 4 118 CYS 118 96   96  CYS CYS N . n 
D 4 119 ALA 119 97   97  ALA ALA N . n 
D 4 120 ARG 120 98   98  ARG ARG N . n 
D 4 121 CYS 121 99   99  CYS CYS N . n 
D 4 122 PRO 122 100  100 PRO PRO N . n 
D 4 123 ALA 123 101  101 ALA ALA N . n 
D 4 124 PRO 124 102  102 PRO PRO N . n 
D 4 125 PHE 125 103  103 PHE PHE N . n 
D 4 126 THR 126 104  104 THR THR N . n 
D 4 127 ARG 127 105  105 ARG ARG N . n 
D 4 128 ASP 128 106  106 ASP ASP N . n 
D 4 129 CYS 129 107  107 CYS CYS N . n 
D 4 130 PHE 130 108  108 PHE PHE N . n 
D 4 131 ASP 131 109  109 ASP ASP N . n 
D 4 132 VAL 132 110  110 VAL VAL N . n 
D 4 133 THR 133 111  111 THR THR N . n 
D 4 134 SER 134 112  112 SER SER N . n 
D 4 135 THR 135 113  113 THR THR N . n 
D 4 136 THR 136 114  114 THR THR N . n 
D 4 137 TYR 137 115  115 TYR TYR N . n 
D 4 138 ALA 138 116  116 ALA ALA N . n 
D 4 139 TYR 139 117  117 TYR TYR N . n 
D 4 140 ARG 140 118  118 ARG ARG N . n 
D 4 141 GLY 141 119  119 GLY GLY N . n 
D 4 142 GLN 142 120  120 GLN GLN N . n 
D 4 143 GLY 143 121  121 GLY GLY N . n 
D 4 144 THR 144 122  122 THR THR N . n 
D 4 145 GLN 145 123  123 GLN GLN N . n 
D 4 146 VAL 146 124  124 VAL VAL N . n 
D 4 147 THR 147 125  125 THR THR N . n 
D 4 148 VAL 148 126  126 VAL VAL N . n 
D 4 149 SER 149 127  ?   ?   ?   N . n 
D 4 150 SER 150 128  ?   ?   ?   N . n 
D 4 151 HIS 151 129  ?   ?   ?   N . n 
D 4 152 HIS 152 130  ?   ?   ?   N . n 
D 4 153 HIS 153 131  ?   ?   ?   N . n 
D 4 154 HIS 154 132  ?   ?   ?   N . n 
D 4 155 HIS 155 133  ?   ?   ?   N . n 
D 4 156 HIS 156 134  ?   ?   ?   N . n 
D 4 157 GLU 157 135  ?   ?   ?   N . n 
D 4 158 PRO 158 136  ?   ?   ?   N . n 
D 4 159 GLU 159 137  ?   ?   ?   N . n 
D 4 160 ALA 160 138  ?   ?   ?   N . n 
E 5 1   SER 1   1    1   SER SER L . n 
E 5 2   TYR 2   2    2   TYR TYR L . n 
E 5 3   SER 3   3    3   SER SER L . n 
E 5 4   MET 4   4    4   MET MET L . n 
E 5 5   GLU 5   5    5   GLU GLU L . n 
E 5 6   HIS 6   6    6   HIS HIS L . n 
E 5 7   PHE 7   7    7   PHE PHE L . n 
E 5 8   ARG 8   8    8   ARG ARG L . n 
E 5 9   TRP 9   9    9   TRP TRP L . n 
E 5 10  GLY 10  10   10  GLY GLY L . n 
E 5 11  LYS 11  11   11  LYS LYS L . n 
E 5 12  PRO 12  12   12  PRO PRO L . n 
E 5 13  VAL 13  13   13  VAL VAL L . n 
F 6 1   MET 1   1    ?   ?   ?   A . n 
F 6 2   GLY 2   2    ?   ?   ?   A . n 
F 6 3   CYS 3   3    ?   ?   ?   A . n 
F 6 4   LEU 4   4    ?   ?   ?   A . n 
F 6 5   GLY 5   5    ?   ?   ?   A . n 
F 6 6   ASN 6   6    ?   ?   ?   A . n 
F 6 7   SER 7   7    ?   ?   ?   A . n 
F 6 8   LYS 8   8    ?   ?   ?   A . n 
F 6 9   THR 9   9    ?   ?   ?   A . n 
F 6 10  GLU 10  10   ?   ?   ?   A . n 
F 6 11  ASP 11  11   ?   ?   ?   A . n 
F 6 12  GLN 12  12   ?   ?   ?   A . n 
F 6 13  ARG 13  13   ?   ?   ?   A . n 
F 6 14  ASN 14  14   ?   ?   ?   A . n 
F 6 15  GLU 15  15   15  GLU GLU A . n 
F 6 16  GLU 16  16   16  GLU GLU A . n 
F 6 17  LYS 17  17   17  LYS LYS A . n 
F 6 18  ALA 18  18   18  ALA ALA A . n 
F 6 19  GLN 19  19   19  GLN GLN A . n 
F 6 20  ARG 20  20   20  ARG ARG A . n 
F 6 21  GLU 21  21   21  GLU GLU A . n 
F 6 22  ALA 22  22   22  ALA ALA A . n 
F 6 23  ASN 23  23   23  ASN ASN A . n 
F 6 24  LYS 24  24   24  LYS LYS A . n 
F 6 25  LYS 25  25   25  LYS LYS A . n 
F 6 26  ILE 26  26   26  ILE ILE A . n 
F 6 27  GLU 27  27   27  GLU GLU A . n 
F 6 28  LYS 28  28   28  LYS LYS A . n 
F 6 29  GLN 29  29   29  GLN GLN A . n 
F 6 30  LEU 30  30   30  LEU LEU A . n 
F 6 31  GLN 31  31   31  GLN GLN A . n 
F 6 32  LYS 32  32   32  LYS LYS A . n 
F 6 33  ASP 33  33   33  ASP ASP A . n 
F 6 34  LYS 34  34   34  LYS LYS A . n 
F 6 35  GLN 35  35   35  GLN GLN A . n 
F 6 36  VAL 36  36   36  VAL VAL A . n 
F 6 37  TYR 37  37   37  TYR TYR A . n 
F 6 38  ARG 38  38   38  ARG ARG A . n 
F 6 39  ALA 39  39   39  ALA ALA A . n 
F 6 40  THR 40  40   40  THR THR A . n 
F 6 41  HIS 41  41   41  HIS HIS A . n 
F 6 42  ARG 42  42   42  ARG ARG A . n 
F 6 43  LEU 43  43   43  LEU LEU A . n 
F 6 44  LEU 44  44   44  LEU LEU A . n 
F 6 45  LEU 45  45   45  LEU LEU A . n 
F 6 46  LEU 46  46   46  LEU LEU A . n 
F 6 47  GLY 47  47   47  GLY GLY A . n 
F 6 48  ALA 48  48   48  ALA ALA A . n 
F 6 49  GLY 49  49   49  GLY GLY A . n 
F 6 50  GLU 50  64   ?   ?   ?   A . n 
F 6 51  SER 51  65   ?   ?   ?   A . n 
F 6 52  GLY 52  66   ?   ?   ?   A . n 
F 6 53  LYS 53  67   ?   ?   ?   A . n 
F 6 54  SER 54  68   ?   ?   ?   A . n 
F 6 55  THR 55  69   ?   ?   ?   A . n 
F 6 56  ILE 56  70   ?   ?   ?   A . n 
F 6 57  VAL 57  71   ?   ?   ?   A . n 
F 6 58  LYS 58  72   ?   ?   ?   A . n 
F 6 59  GLN 59  73   ?   ?   ?   A . n 
F 6 60  MET 60  74   ?   ?   ?   A . n 
F 6 61  ARG 61  75   ?   ?   ?   A . n 
F 6 62  ILE 62  76   ?   ?   ?   A . n 
F 6 63  LEU 63  77   ?   ?   ?   A . n 
F 6 64  HIS 64  78   ?   ?   ?   A . n 
F 6 65  VAL 65  79   ?   ?   ?   A . n 
F 6 66  ASN 66  80   ?   ?   ?   A . n 
F 6 67  GLY 67  81   ?   ?   ?   A . n 
F 6 68  PHE 68  82   ?   ?   ?   A . n 
F 6 69  ASN 69  83   ?   ?   ?   A . n 
F 6 70  GLY 70  84   ?   ?   ?   A . n 
F 6 71  ASP 71  85   ?   ?   ?   A . n 
F 6 72  SER 72  86   ?   ?   ?   A . n 
F 6 73  GLU 73  87   ?   ?   ?   A . n 
F 6 74  LYS 74  88   ?   ?   ?   A . n 
F 6 75  ALA 75  89   ?   ?   ?   A . n 
F 6 76  THR 76  90   ?   ?   ?   A . n 
F 6 77  LYS 77  91   ?   ?   ?   A . n 
F 6 78  VAL 78  92   ?   ?   ?   A . n 
F 6 79  GLN 79  93   ?   ?   ?   A . n 
F 6 80  ASP 80  94   ?   ?   ?   A . n 
F 6 81  ILE 81  95   ?   ?   ?   A . n 
F 6 82  LYS 82  96   ?   ?   ?   A . n 
F 6 83  ASN 83  97   ?   ?   ?   A . n 
F 6 84  ASN 84  98   ?   ?   ?   A . n 
F 6 85  LEU 85  99   ?   ?   ?   A . n 
F 6 86  LYS 86  100  ?   ?   ?   A . n 
F 6 87  GLU 87  101  ?   ?   ?   A . n 
F 6 88  ALA 88  102  ?   ?   ?   A . n 
F 6 89  ILE 89  103  ?   ?   ?   A . n 
F 6 90  GLU 90  104  ?   ?   ?   A . n 
F 6 91  THR 91  105  ?   ?   ?   A . n 
F 6 92  ILE 92  106  ?   ?   ?   A . n 
F 6 93  VAL 93  107  ?   ?   ?   A . n 
F 6 94  ALA 94  108  ?   ?   ?   A . n 
F 6 95  ALA 95  109  ?   ?   ?   A . n 
F 6 96  MET 96  110  ?   ?   ?   A . n 
F 6 97  SER 97  111  ?   ?   ?   A . n 
F 6 98  ASN 98  112  ?   ?   ?   A . n 
F 6 99  LEU 99  113  ?   ?   ?   A . n 
F 6 100 VAL 100 114  ?   ?   ?   A . n 
F 6 101 PRO 101 115  ?   ?   ?   A . n 
F 6 102 PRO 102 116  ?   ?   ?   A . n 
F 6 103 VAL 103 117  ?   ?   ?   A . n 
F 6 104 GLU 104 118  ?   ?   ?   A . n 
F 6 105 LEU 105 119  ?   ?   ?   A . n 
F 6 106 ALA 106 120  ?   ?   ?   A . n 
F 6 107 ASN 107 121  ?   ?   ?   A . n 
F 6 108 PRO 108 122  ?   ?   ?   A . n 
F 6 109 GLU 109 123  ?   ?   ?   A . n 
F 6 110 ASN 110 124  ?   ?   ?   A . n 
F 6 111 GLN 111 125  ?   ?   ?   A . n 
F 6 112 PHE 112 126  ?   ?   ?   A . n 
F 6 113 ARG 113 127  ?   ?   ?   A . n 
F 6 114 VAL 114 128  ?   ?   ?   A . n 
F 6 115 ASP 115 129  ?   ?   ?   A . n 
F 6 116 TYR 116 130  ?   ?   ?   A . n 
F 6 117 ILE 117 131  ?   ?   ?   A . n 
F 6 118 LEU 118 132  ?   ?   ?   A . n 
F 6 119 SER 119 133  ?   ?   ?   A . n 
F 6 120 VAL 120 134  ?   ?   ?   A . n 
F 6 121 MET 121 135  ?   ?   ?   A . n 
F 6 122 ASN 122 136  ?   ?   ?   A . n 
F 6 123 VAL 123 137  ?   ?   ?   A . n 
F 6 124 PRO 124 138  ?   ?   ?   A . n 
F 6 125 ASP 125 139  ?   ?   ?   A . n 
F 6 126 PHE 126 140  ?   ?   ?   A . n 
F 6 127 ASP 127 141  ?   ?   ?   A . n 
F 6 128 PHE 128 142  ?   ?   ?   A . n 
F 6 129 PRO 129 143  ?   ?   ?   A . n 
F 6 130 PRO 130 144  ?   ?   ?   A . n 
F 6 131 GLU 131 145  ?   ?   ?   A . n 
F 6 132 PHE 132 146  ?   ?   ?   A . n 
F 6 133 TYR 133 147  ?   ?   ?   A . n 
F 6 134 GLU 134 148  ?   ?   ?   A . n 
F 6 135 HIS 135 149  ?   ?   ?   A . n 
F 6 136 ALA 136 150  ?   ?   ?   A . n 
F 6 137 LYS 137 151  ?   ?   ?   A . n 
F 6 138 ALA 138 152  ?   ?   ?   A . n 
F 6 139 LEU 139 153  ?   ?   ?   A . n 
F 6 140 TRP 140 154  ?   ?   ?   A . n 
F 6 141 GLU 141 155  ?   ?   ?   A . n 
F 6 142 ASP 142 156  ?   ?   ?   A . n 
F 6 143 GLU 143 157  ?   ?   ?   A . n 
F 6 144 GLY 144 158  ?   ?   ?   A . n 
F 6 145 VAL 145 159  ?   ?   ?   A . n 
F 6 146 ARG 146 160  ?   ?   ?   A . n 
F 6 147 ALA 147 161  ?   ?   ?   A . n 
F 6 148 CYS 148 162  ?   ?   ?   A . n 
F 6 149 TYR 149 163  ?   ?   ?   A . n 
F 6 150 GLU 150 164  ?   ?   ?   A . n 
F 6 151 ARG 151 165  ?   ?   ?   A . n 
F 6 152 SER 152 166  ?   ?   ?   A . n 
F 6 153 ASN 153 167  ?   ?   ?   A . n 
F 6 154 GLU 154 168  ?   ?   ?   A . n 
F 6 155 TYR 155 169  ?   ?   ?   A . n 
F 6 156 GLN 156 170  ?   ?   ?   A . n 
F 6 157 LEU 157 171  ?   ?   ?   A . n 
F 6 158 ILE 158 172  ?   ?   ?   A . n 
F 6 159 ASP 159 173  ?   ?   ?   A . n 
F 6 160 CYS 160 174  ?   ?   ?   A . n 
F 6 161 ALA 161 175  ?   ?   ?   A . n 
F 6 162 GLN 162 176  ?   ?   ?   A . n 
F 6 163 TYR 163 177  ?   ?   ?   A . n 
F 6 164 PHE 164 178  ?   ?   ?   A . n 
F 6 165 LEU 165 179  ?   ?   ?   A . n 
F 6 166 ASP 166 180  ?   ?   ?   A . n 
F 6 167 LYS 167 181  ?   ?   ?   A . n 
F 6 168 ILE 168 182  ?   ?   ?   A . n 
F 6 169 ASP 169 183  ?   ?   ?   A . n 
F 6 170 VAL 170 184  ?   ?   ?   A . n 
F 6 171 ILE 171 185  ?   ?   ?   A . n 
F 6 172 LYS 172 186  ?   ?   ?   A . n 
F 6 173 GLN 173 187  ?   ?   ?   A . n 
F 6 174 ALA 174 188  ?   ?   ?   A . n 
F 6 175 ASP 175 189  ?   ?   ?   A . n 
F 6 176 TYR 176 190  ?   ?   ?   A . n 
F 6 177 VAL 177 191  ?   ?   ?   A . n 
F 6 178 PRO 178 192  ?   ?   ?   A . n 
F 6 179 SER 179 193  ?   ?   ?   A . n 
F 6 180 ASP 180 194  ?   ?   ?   A . n 
F 6 181 GLN 181 195  ?   ?   ?   A . n 
F 6 182 ASP 182 196  ?   ?   ?   A . n 
F 6 183 LEU 183 197  ?   ?   ?   A . n 
F 6 184 LEU 184 198  ?   ?   ?   A . n 
F 6 185 ARG 185 199  ?   ?   ?   A . n 
F 6 186 CYS 186 200  ?   ?   ?   A . n 
F 6 187 ARG 187 201  ?   ?   ?   A . n 
F 6 188 VAL 188 202  ?   ?   ?   A . n 
F 6 189 LEU 189 203  ?   ?   ?   A . n 
F 6 190 THR 190 204  ?   ?   ?   A . n 
F 6 191 SER 191 205  ?   ?   ?   A . n 
F 6 192 GLY 192 206  ?   ?   ?   A . n 
F 6 193 ILE 193 207  ?   ?   ?   A . n 
F 6 194 PHE 194 208  208 PHE PHE A . n 
F 6 195 GLU 195 209  209 GLU GLU A . n 
F 6 196 THR 196 210  210 THR THR A . n 
F 6 197 LYS 197 211  211 LYS LYS A . n 
F 6 198 PHE 198 212  212 PHE PHE A . n 
F 6 199 GLN 199 213  213 GLN GLN A . n 
F 6 200 VAL 200 214  214 VAL VAL A . n 
F 6 201 ASP 201 215  215 ASP ASP A . n 
F 6 202 LYS 202 216  216 LYS LYS A . n 
F 6 203 VAL 203 217  217 VAL VAL A . n 
F 6 204 ASN 204 218  218 ASN ASN A . n 
F 6 205 PHE 205 219  219 PHE PHE A . n 
F 6 206 HIS 206 220  220 HIS HIS A . n 
F 6 207 MET 207 221  221 MET MET A . n 
F 6 208 PHE 208 222  222 PHE PHE A . n 
F 6 209 ASP 209 223  223 ASP ASP A . n 
F 6 210 VAL 210 224  224 VAL VAL A . n 
F 6 211 GLY 211 225  225 GLY GLY A . n 
F 6 212 GLY 212 226  226 GLY GLY A . n 
F 6 213 GLN 213 227  227 GLN GLN A . n 
F 6 214 ARG 214 228  228 ARG ARG A . n 
F 6 215 ASP 215 229  229 ASP ASP A . n 
F 6 216 GLU 216 230  230 GLU GLU A . n 
F 6 217 ARG 217 231  231 ARG ARG A . n 
F 6 218 ARG 218 232  232 ARG ARG A . n 
F 6 219 LYS 219 233  233 LYS LYS A . n 
F 6 220 TRP 220 234  234 TRP TRP A . n 
F 6 221 ILE 221 235  235 ILE ILE A . n 
F 6 222 GLN 222 236  236 GLN GLN A . n 
F 6 223 CYS 223 237  237 CYS CYS A . n 
F 6 224 PHE 224 238  238 PHE PHE A . n 
F 6 225 ASN 225 239  239 ASN ASN A . n 
F 6 226 ASP 226 240  240 ASP ASP A . n 
F 6 227 VAL 227 241  241 VAL VAL A . n 
F 6 228 THR 228 242  242 THR THR A . n 
F 6 229 ALA 229 243  243 ALA ALA A . n 
F 6 230 ILE 230 244  244 ILE ILE A . n 
F 6 231 ILE 231 245  245 ILE ILE A . n 
F 6 232 PHE 232 246  246 PHE PHE A . n 
F 6 233 VAL 233 247  247 VAL VAL A . n 
F 6 234 VAL 234 248  248 VAL VAL A . n 
F 6 235 ALA 235 249  249 ALA ALA A . n 
F 6 236 SER 236 250  ?   ?   ?   A . n 
F 6 237 SER 237 251  ?   ?   ?   A . n 
F 6 238 SER 238 252  ?   ?   ?   A . n 
F 6 239 TYR 239 253  ?   ?   ?   A . n 
F 6 240 ASN 240 254  ?   ?   ?   A . n 
F 6 241 MET 241 255  ?   ?   ?   A . n 
F 6 242 VAL 242 256  ?   ?   ?   A . n 
F 6 243 ILE 243 257  ?   ?   ?   A . n 
F 6 244 ARG 244 258  ?   ?   ?   A . n 
F 6 245 GLU 245 259  ?   ?   ?   A . n 
F 6 246 ASP 246 260  ?   ?   ?   A . n 
F 6 247 ASN 247 261  ?   ?   ?   A . n 
F 6 248 GLN 248 262  ?   ?   ?   A . n 
F 6 249 THR 249 263  ?   ?   ?   A . n 
F 6 250 ASN 250 264  264 ASN ASN A . n 
F 6 251 ARG 251 265  265 ARG ARG A . n 
F 6 252 LEU 252 266  266 LEU LEU A . n 
F 6 253 GLN 253 267  267 GLN GLN A . n 
F 6 254 GLU 254 268  268 GLU GLU A . n 
F 6 255 ALA 255 269  269 ALA ALA A . n 
F 6 256 LEU 256 270  270 LEU LEU A . n 
F 6 257 ASN 257 271  271 ASN ASN A . n 
F 6 258 LEU 258 272  272 LEU LEU A . n 
F 6 259 PHE 259 273  273 PHE PHE A . n 
F 6 260 LYS 260 274  274 LYS LYS A . n 
F 6 261 SER 261 275  275 SER SER A . n 
F 6 262 ILE 262 276  276 ILE ILE A . n 
F 6 263 TRP 263 277  277 TRP TRP A . n 
F 6 264 ASN 264 278  278 ASN ASN A . n 
F 6 265 ASN 265 279  279 ASN ASN A . n 
F 6 266 ARG 266 280  280 ARG ARG A . n 
F 6 267 TRP 267 281  281 TRP TRP A . n 
F 6 268 LEU 268 282  282 LEU LEU A . n 
F 6 269 ARG 269 283  283 ARG ARG A . n 
F 6 270 THR 270 284  284 THR THR A . n 
F 6 271 ILE 271 285  285 ILE ILE A . n 
F 6 272 SER 272 286  286 SER SER A . n 
F 6 273 VAL 273 287  287 VAL VAL A . n 
F 6 274 ILE 274 288  288 ILE ILE A . n 
F 6 275 LEU 275 289  289 LEU LEU A . n 
F 6 276 PHE 276 290  290 PHE PHE A . n 
F 6 277 LEU 277 291  291 LEU LEU A . n 
F 6 278 ASN 278 292  292 ASN ASN A . n 
F 6 279 LYS 279 293  293 LYS LYS A . n 
F 6 280 GLN 280 294  294 GLN GLN A . n 
F 6 281 ASP 281 295  ?   ?   ?   A . n 
F 6 282 LEU 282 296  ?   ?   ?   A . n 
F 6 283 LEU 283 297  ?   ?   ?   A . n 
F 6 284 ALA 284 298  ?   ?   ?   A . n 
F 6 285 GLU 285 299  ?   ?   ?   A . n 
F 6 286 LYS 286 300  ?   ?   ?   A . n 
F 6 287 VAL 287 301  ?   ?   ?   A . n 
F 6 288 LEU 288 302  ?   ?   ?   A . n 
F 6 289 ALA 289 303  ?   ?   ?   A . n 
F 6 290 GLY 290 304  ?   ?   ?   A . n 
F 6 291 LYS 291 305  ?   ?   ?   A . n 
F 6 292 SER 292 306  ?   ?   ?   A . n 
F 6 293 LYS 293 307  ?   ?   ?   A . n 
F 6 294 ILE 294 308  308 ILE ILE A . n 
F 6 295 GLU 295 309  309 GLU GLU A . n 
F 6 296 ASP 296 310  310 ASP ASP A . n 
F 6 297 TYR 297 311  311 TYR TYR A . n 
F 6 298 PHE 298 312  312 PHE PHE A . n 
F 6 299 PRO 299 313  313 PRO PRO A . n 
F 6 300 GLU 300 314  314 GLU GLU A . n 
F 6 301 PHE 301 315  315 PHE PHE A . n 
F 6 302 ALA 302 316  316 ALA ALA A . n 
F 6 303 ARG 303 317  317 ARG ARG A . n 
F 6 304 TYR 304 318  318 TYR TYR A . n 
F 6 305 THR 305 319  319 THR THR A . n 
F 6 306 THR 306 320  320 THR THR A . n 
F 6 307 PRO 307 321  ?   ?   ?   A . n 
F 6 308 GLU 308 322  ?   ?   ?   A . n 
F 6 309 ASP 309 323  ?   ?   ?   A . n 
F 6 310 ALA 310 324  ?   ?   ?   A . n 
F 6 311 THR 311 325  ?   ?   ?   A . n 
F 6 312 PRO 312 326  ?   ?   ?   A . n 
F 6 313 GLU 313 327  ?   ?   ?   A . n 
F 6 314 PRO 314 328  ?   ?   ?   A . n 
F 6 315 GLY 315 329  ?   ?   ?   A . n 
F 6 316 GLU 316 330  ?   ?   ?   A . n 
F 6 317 ASP 317 331  331 ASP ASP A . n 
F 6 318 PRO 318 332  332 PRO PRO A . n 
F 6 319 ARG 319 333  333 ARG ARG A . n 
F 6 320 VAL 320 334  334 VAL VAL A . n 
F 6 321 THR 321 335  335 THR THR A . n 
F 6 322 ARG 322 336  336 ARG ARG A . n 
F 6 323 ALA 323 337  337 ALA ALA A . n 
F 6 324 LYS 324 338  338 LYS LYS A . n 
F 6 325 TYR 325 339  339 TYR TYR A . n 
F 6 326 PHE 326 340  340 PHE PHE A . n 
F 6 327 ILE 327 341  341 ILE ILE A . n 
F 6 328 ARG 328 342  342 ARG ARG A . n 
F 6 329 ASP 329 343  343 ASP ASP A . n 
F 6 330 GLU 330 344  344 GLU GLU A . n 
F 6 331 PHE 331 345  345 PHE PHE A . n 
F 6 332 LEU 332 346  346 LEU LEU A . n 
F 6 333 ARG 333 347  347 ARG ARG A . n 
F 6 334 ILE 334 348  348 ILE ILE A . n 
F 6 335 SER 335 349  349 SER SER A . n 
F 6 336 THR 336 350  350 THR THR A . n 
F 6 337 ALA 337 351  351 ALA ALA A . n 
F 6 338 SER 338 352  352 SER SER A . n 
F 6 339 GLY 339 353  353 GLY GLY A . n 
F 6 340 ASP 340 354  354 ASP ASP A . n 
F 6 341 GLY 341 355  355 GLY GLY A . n 
F 6 342 ARG 342 356  356 ARG ARG A . n 
F 6 343 HIS 343 357  357 HIS HIS A . n 
F 6 344 TYR 344 358  358 TYR TYR A . n 
F 6 345 CYS 345 359  359 CYS CYS A . n 
F 6 346 TYR 346 360  360 TYR TYR A . n 
F 6 347 PRO 347 361  361 PRO PRO A . n 
F 6 348 HIS 348 362  362 HIS HIS A . n 
F 6 349 PHE 349 363  363 PHE PHE A . n 
F 6 350 THR 350 364  364 THR THR A . n 
F 6 351 CYS 351 365  365 CYS CYS A . n 
F 6 352 ALA 352 366  366 ALA ALA A . n 
F 6 353 VAL 353 367  367 VAL VAL A . n 
F 6 354 ASP 354 368  368 ASP ASP A . n 
F 6 355 THR 355 369  369 THR THR A . n 
F 6 356 GLU 356 370  370 GLU GLU A . n 
F 6 357 ASN 357 371  371 ASN ASN A . n 
F 6 358 ILE 358 372  372 ILE ILE A . n 
F 6 359 ARG 359 373  373 ARG ARG A . n 
F 6 360 ARG 360 374  374 ARG ARG A . n 
F 6 361 VAL 361 375  375 VAL VAL A . n 
F 6 362 PHE 362 376  376 PHE PHE A . n 
F 6 363 ASN 363 377  377 ASN ASN A . n 
F 6 364 ASP 364 378  378 ASP ASP A . n 
F 6 365 CYS 365 379  379 CYS CYS A . n 
F 6 366 ARG 366 380  380 ARG ARG A . n 
F 6 367 ASP 367 381  381 ASP ASP A . n 
F 6 368 ILE 368 382  382 ILE ILE A . n 
F 6 369 ILE 369 383  383 ILE ILE A . n 
F 6 370 GLN 370 384  384 GLN GLN A . n 
F 6 371 ARG 371 385  385 ARG ARG A . n 
F 6 372 MET 372 386  386 MET MET A . n 
F 6 373 HIS 373 387  387 HIS HIS A . n 
F 6 374 LEU 374 388  388 LEU LEU A . n 
F 6 375 ARG 375 389  389 ARG ARG A . n 
F 6 376 GLN 376 390  390 GLN GLN A . n 
F 6 377 TYR 377 391  391 TYR TYR A . n 
F 6 378 GLU 378 392  392 GLU GLU A . n 
F 6 379 LEU 379 393  393 LEU LEU A . n 
F 6 380 LEU 380 394  394 LEU LEU A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        CA 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   CA 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
_pdbx_nonpoly_scheme.asym_id         G 
_pdbx_nonpoly_scheme.entity_id       7 
_pdbx_nonpoly_scheme.mon_id          CA 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     501 
_pdbx_nonpoly_scheme.auth_seq_num    401 
_pdbx_nonpoly_scheme.pdb_mon_id      CA 
_pdbx_nonpoly_scheme.auth_mon_id     CA 
_pdbx_nonpoly_scheme.pdb_strand_id   R 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1   1 Y 1 R ASN 68  ? CG  ? A ASN 189 CG  
2   1 Y 1 R ASN 68  ? OD1 ? A ASN 189 OD1 
3   1 Y 1 R ASN 68  ? ND2 ? A ASN 189 ND2 
4   1 Y 1 R LYS 219 ? CG  ? A LYS 340 CG  
5   1 Y 1 R LYS 219 ? CD  ? A LYS 340 CD  
6   1 Y 1 R LYS 219 ? CE  ? A LYS 340 CE  
7   1 Y 1 R LYS 219 ? NZ  ? A LYS 340 NZ  
8   1 Y 1 B ARG 46  ? CG  ? B ARG 64  CG  
9   1 Y 1 B ARG 46  ? CD  ? B ARG 64  CD  
10  1 Y 1 B ARG 46  ? NE  ? B ARG 64  NE  
11  1 Y 1 B ARG 46  ? CZ  ? B ARG 64  CZ  
12  1 Y 1 B ARG 46  ? NH1 ? B ARG 64  NH1 
13  1 Y 1 B ARG 46  ? NH2 ? B ARG 64  NH2 
14  1 Y 1 A LYS 17  ? CG  ? F LYS 17  CG  
15  1 Y 1 A LYS 17  ? CD  ? F LYS 17  CD  
16  1 Y 1 A LYS 17  ? CE  ? F LYS 17  CE  
17  1 Y 1 A LYS 17  ? NZ  ? F LYS 17  NZ  
18  1 Y 1 A LYS 28  ? CG  ? F LYS 28  CG  
19  1 Y 1 A LYS 28  ? CD  ? F LYS 28  CD  
20  1 Y 1 A LYS 28  ? CE  ? F LYS 28  CE  
21  1 Y 1 A LYS 28  ? NZ  ? F LYS 28  NZ  
22  1 Y 1 A GLU 209 ? CG  ? F GLU 195 CG  
23  1 Y 1 A GLU 209 ? CD  ? F GLU 195 CD  
24  1 Y 1 A GLU 209 ? OE1 ? F GLU 195 OE1 
25  1 Y 1 A GLU 209 ? OE2 ? F GLU 195 OE2 
26  1 Y 1 A THR 210 ? OG1 ? F THR 196 OG1 
27  1 Y 1 A THR 210 ? CG2 ? F THR 196 CG2 
28  1 Y 1 A ARG 228 ? CG  ? F ARG 214 CG  
29  1 Y 1 A ARG 228 ? CD  ? F ARG 214 CD  
30  1 Y 1 A ARG 228 ? NE  ? F ARG 214 NE  
31  1 Y 1 A ARG 228 ? CZ  ? F ARG 214 CZ  
32  1 Y 1 A ARG 228 ? NH1 ? F ARG 214 NH1 
33  1 Y 1 A ARG 228 ? NH2 ? F ARG 214 NH2 
34  1 Y 1 A ASP 229 ? CG  ? F ASP 215 CG  
35  1 Y 1 A ASP 229 ? OD1 ? F ASP 215 OD1 
36  1 Y 1 A ASP 229 ? OD2 ? F ASP 215 OD2 
37  1 Y 1 A ASP 240 ? CG  ? F ASP 226 CG  
38  1 Y 1 A ASP 240 ? OD1 ? F ASP 226 OD1 
39  1 Y 1 A ASP 240 ? OD2 ? F ASP 226 OD2 
40  1 Y 1 A LYS 293 ? CG  ? F LYS 279 CG  
41  1 Y 1 A LYS 293 ? CD  ? F LYS 279 CD  
42  1 Y 1 A LYS 293 ? CE  ? F LYS 279 CE  
43  1 Y 1 A LYS 293 ? NZ  ? F LYS 279 NZ  
44  1 Y 1 A GLN 294 ? CG  ? F GLN 280 CG  
45  1 Y 1 A GLN 294 ? CD  ? F GLN 280 CD  
46  1 Y 1 A GLN 294 ? OE1 ? F GLN 280 OE1 
47  1 Y 1 A GLN 294 ? NE2 ? F GLN 280 NE2 
48  1 Y 1 A ILE 308 ? CG1 ? F ILE 294 CG1 
49  1 Y 1 A ILE 308 ? CG2 ? F ILE 294 CG2 
50  1 Y 1 A ILE 308 ? CD1 ? F ILE 294 CD1 
51  1 Y 1 A GLU 309 ? CG  ? F GLU 295 CG  
52  1 Y 1 A GLU 309 ? CD  ? F GLU 295 CD  
53  1 Y 1 A GLU 309 ? OE1 ? F GLU 295 OE1 
54  1 Y 1 A GLU 309 ? OE2 ? F GLU 295 OE2 
55  1 Y 1 A ASP 310 ? CG  ? F ASP 296 CG  
56  1 Y 1 A ASP 310 ? OD1 ? F ASP 296 OD1 
57  1 Y 1 A ASP 310 ? OD2 ? F ASP 296 OD2 
58  1 Y 1 A TYR 311 ? CG  ? F TYR 297 CG  
59  1 Y 1 A TYR 311 ? CD1 ? F TYR 297 CD1 
60  1 Y 1 A TYR 311 ? CD2 ? F TYR 297 CD2 
61  1 Y 1 A TYR 311 ? CE1 ? F TYR 297 CE1 
62  1 Y 1 A TYR 311 ? CE2 ? F TYR 297 CE2 
63  1 Y 1 A TYR 311 ? CZ  ? F TYR 297 CZ  
64  1 Y 1 A TYR 311 ? OH  ? F TYR 297 OH  
65  1 Y 1 A ARG 317 ? CG  ? F ARG 303 CG  
66  1 Y 1 A ARG 317 ? CD  ? F ARG 303 CD  
67  1 Y 1 A ARG 317 ? NE  ? F ARG 303 NE  
68  1 Y 1 A ARG 317 ? CZ  ? F ARG 303 CZ  
69  1 Y 1 A ARG 317 ? NH1 ? F ARG 303 NH1 
70  1 Y 1 A ARG 317 ? NH2 ? F ARG 303 NH2 
71  1 Y 1 A ASP 331 ? CG  ? F ASP 317 CG  
72  1 Y 1 A ASP 331 ? OD1 ? F ASP 317 OD1 
73  1 Y 1 A ASP 331 ? OD2 ? F ASP 317 OD2 
74  1 Y 1 A ARG 333 ? CG  ? F ARG 319 CG  
75  1 Y 1 A ARG 333 ? CD  ? F ARG 319 CD  
76  1 Y 1 A ARG 333 ? NE  ? F ARG 319 NE  
77  1 Y 1 A ARG 333 ? CZ  ? F ARG 319 CZ  
78  1 Y 1 A ARG 333 ? NH1 ? F ARG 319 NH1 
79  1 Y 1 A ARG 333 ? NH2 ? F ARG 319 NH2 
80  1 Y 1 A ARG 336 ? CG  ? F ARG 322 CG  
81  1 Y 1 A ARG 336 ? CD  ? F ARG 322 CD  
82  1 Y 1 A ARG 336 ? NE  ? F ARG 322 NE  
83  1 Y 1 A ARG 336 ? CZ  ? F ARG 322 CZ  
84  1 Y 1 A ARG 336 ? NH1 ? F ARG 322 NH1 
85  1 Y 1 A ARG 336 ? NH2 ? F ARG 322 NH2 
86  1 Y 1 A ASP 343 ? CG  ? F ASP 329 CG  
87  1 Y 1 A ASP 343 ? OD1 ? F ASP 329 OD1 
88  1 Y 1 A ASP 343 ? OD2 ? F ASP 329 OD2 
89  1 Y 1 A ARG 347 ? CG  ? F ARG 333 CG  
90  1 Y 1 A ARG 347 ? CD  ? F ARG 333 CD  
91  1 Y 1 A ARG 347 ? NE  ? F ARG 333 NE  
92  1 Y 1 A ARG 347 ? CZ  ? F ARG 333 CZ  
93  1 Y 1 A ARG 347 ? NH1 ? F ARG 333 NH1 
94  1 Y 1 A ARG 347 ? NH2 ? F ARG 333 NH2 
95  1 Y 1 A ASP 354 ? CG  ? F ASP 340 CG  
96  1 Y 1 A ASP 354 ? OD1 ? F ASP 340 OD1 
97  1 Y 1 A ASP 354 ? OD2 ? F ASP 340 OD2 
98  1 Y 1 A VAL 367 ? CG1 ? F VAL 353 CG1 
99  1 Y 1 A VAL 367 ? CG2 ? F VAL 353 CG2 
100 1 Y 1 A ASP 368 ? CG  ? F ASP 354 CG  
101 1 Y 1 A ASP 368 ? OD1 ? F ASP 354 OD1 
102 1 Y 1 A ASP 368 ? OD2 ? F ASP 354 OD2 
103 1 Y 1 A THR 369 ? OG1 ? F THR 355 OG1 
104 1 Y 1 A THR 369 ? CG2 ? F THR 355 CG2 
105 1 Y 1 A GLU 370 ? CG  ? F GLU 356 CG  
106 1 Y 1 A GLU 370 ? CD  ? F GLU 356 CD  
107 1 Y 1 A GLU 370 ? OE1 ? F GLU 356 OE1 
108 1 Y 1 A GLU 370 ? OE2 ? F GLU 356 OE2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8W8W 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8W8W 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8W8W 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8W8W 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            . 
_refine.ls_d_res_low                             ? 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.006 ? 7810  ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.646 ? 10586 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 5.008 ? 1056  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.047 ? 1210  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.006 ? 1342  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8W8W 
_struct.title                        'Cryo-EM structure of alpha-MSH-MC3R-Gs_Nb35 complex' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8W8W 
_struct_keywords.text            'alpha-MSH, MC3R, MEMBRANE PROTEIN' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 4 ? 
E N N 5 ? 
F N N 6 ? 
G N N 7 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP C562_ECOLX  P0ABE7 ?        1 
;ADLEDNMETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLAN
EGKVKEAQAAAEQLKTTRNAYHQKY
;
23  
2 UNP MC3R_HUMAN  P41968 ?        1 
;NASCCLPSVQPTLPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLA
VADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKA
LTLIVAIWVCCGVCGVVFIVYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKGA
VTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILCGCNGMN
LG
;
2   
3 PDB 8W8W        8W8W   ?        1 ? 445 
4 UNP GBB1_RAT    P54311 ?        2 
;SELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLII
WDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSS
GDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAF
ATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVT
DDGMAVATGSWDSFLKIWN
;
2   
5 UNP GBG2_BOVIN  P63212 ?        3 MASNNTASIAQARKLVEQLKMEANIDRIKVSKAAADLMAYCEAHAKEDPLLTPVPASENPFREKKFFCAIL 1   
6 PDB 8W8W        8W8W   ?        4 ? 1   
7 PDB 8W8W        8W8W   ?        5 ? 1   
8 UNP GNAS2_HUMAN P63092 P63092-2 6 
;MGCLGNSKTEDQRNEEKAQREANKKIEKQLQKDKQVYRATHRLLLLGAGESGKSTIVKQMRILHVNGFNGDSEKATKVQD
IKNNLKEAIETIVAAMSNLVPPVELANPENQFRVDYILSVMNVPDFDFPPEFYEHAKALWEDEGVRACYERSNEYQLIDC
AQYFLDKIDVIKQADYVPSDQDLLRCRVLTSGIFETKFQVDKVNFHMFDVGGQRDERRKWIQCFNDVTAIIFVVASSSYN
MVIREDNQTNRLQEALNLFKSIWNNRWLRTISVILFLNKQDLLAEKVLAGKSKIEDYFPEFARYTTPEDATPEPGEDPRV
TRAKYFIRDEFLRISTASGDGRHYCYPHFTCAVDTENIRRVFNDCRDIIQRMHLRQYELL
;
1   
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8W8W R 11  ? 115 ? P0ABE7 23  ? 127 ? -110 -6  
2 2 8W8W R 123 ? 444 ? P41968 2   ? 323 ? 2    323 
3 3 8W8W R 445 ? 602 ? 8W8W   324 ? 481 ? 324  481 
4 4 8W8W B 20  ? 358 ? P54311 2   ? 340 ? 2    340 
5 5 8W8W G 1   ? 71  ? P63212 1   ? 71  ? 1    71  
6 6 8W8W N 1   ? 160 ? 8W8W   -21 ? 138 ? -21  138 
7 7 8W8W L 1   ? 13  ? 8W8W   1   ? 13  ? 1    13  
8 8 8W8W A 1   ? 380 ? P63092 1   ? 380 ? 1    394 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 8W8W ASP R 1   ? UNP P0ABE7 ?   ?   'expression tag'        -120 1  
1 8W8W TYR R 2   ? UNP P0ABE7 ?   ?   'expression tag'        -119 2  
1 8W8W LYS R 3   ? UNP P0ABE7 ?   ?   'expression tag'        -118 3  
1 8W8W ASP R 4   ? UNP P0ABE7 ?   ?   'expression tag'        -117 4  
1 8W8W ASP R 5   ? UNP P0ABE7 ?   ?   'expression tag'        -116 5  
1 8W8W ASP R 6   ? UNP P0ABE7 ?   ?   'expression tag'        -115 6  
1 8W8W ASP R 7   ? UNP P0ABE7 ?   ?   'expression tag'        -114 7  
1 8W8W LYS R 8   ? UNP P0ABE7 ?   ?   'expression tag'        -113 8  
1 8W8W GLY R 9   ? UNP P0ABE7 ?   ?   'expression tag'        -112 9  
1 8W8W SER R 10  ? UNP P0ABE7 ?   ?   'expression tag'        -111 10 
1 8W8W TRP R 17  ? UNP P0ABE7 MET 29  conflict                -104 11 
1 8W8W ILE R 112 ? UNP P0ABE7 HIS 124 conflict                -9   12 
1 8W8W LEU R 116 ? UNP P0ABE7 ?   ?   linker                  -5   13 
1 8W8W LEU R 117 ? UNP P0ABE7 ?   ?   linker                  -4   14 
1 8W8W VAL R 118 ? UNP P0ABE7 ?   ?   linker                  -3   15 
1 8W8W PRO R 119 ? UNP P0ABE7 ?   ?   linker                  -2   16 
1 8W8W ARG R 120 ? UNP P0ABE7 ?   ?   linker                  -1   17 
1 8W8W GLY R 121 ? UNP P0ABE7 ?   ?   linker                  0    18 
1 8W8W SER R 122 ? UNP P0ABE7 ?   ?   linker                  1    19 
4 8W8W MET B 1   ? UNP P54311 ?   ?   'initiating methionine' -17  20 
4 8W8W HIS B 2   ? UNP P54311 ?   ?   'expression tag'        -16  21 
4 8W8W HIS B 3   ? UNP P54311 ?   ?   'expression tag'        -15  22 
4 8W8W HIS B 4   ? UNP P54311 ?   ?   'expression tag'        -14  23 
4 8W8W HIS B 5   ? UNP P54311 ?   ?   'expression tag'        -13  24 
4 8W8W HIS B 6   ? UNP P54311 ?   ?   'expression tag'        -12  25 
4 8W8W HIS B 7   ? UNP P54311 ?   ?   'expression tag'        -11  26 
4 8W8W LEU B 8   ? UNP P54311 ?   ?   'expression tag'        -10  27 
4 8W8W GLU B 9   ? UNP P54311 ?   ?   'expression tag'        -9   28 
4 8W8W VAL B 10  ? UNP P54311 ?   ?   'expression tag'        -8   29 
4 8W8W LEU B 11  ? UNP P54311 ?   ?   'expression tag'        -7   30 
4 8W8W PHE B 12  ? UNP P54311 ?   ?   'expression tag'        -6   31 
4 8W8W GLN B 13  ? UNP P54311 ?   ?   'expression tag'        -5   32 
4 8W8W GLY B 14  ? UNP P54311 ?   ?   'expression tag'        -4   33 
4 8W8W PRO B 15  ? UNP P54311 ?   ?   'expression tag'        -3   34 
4 8W8W GLY B 16  ? UNP P54311 ?   ?   'expression tag'        -2   35 
4 8W8W SER B 17  ? UNP P54311 ?   ?   'expression tag'        -1   36 
4 8W8W SER B 18  ? UNP P54311 ?   ?   'expression tag'        0    37 
4 8W8W GLY B 19  ? UNP P54311 ?   ?   'expression tag'        1    38 
4 8W8W GLY B 359 ? UNP P54311 ?   ?   'expression tag'        341  39 
4 8W8W SER B 360 ? UNP P54311 ?   ?   'expression tag'        342  40 
4 8W8W SER B 361 ? UNP P54311 ?   ?   'expression tag'        343  41 
4 8W8W GLY B 362 ? UNP P54311 ?   ?   'expression tag'        344  42 
4 8W8W GLY B 363 ? UNP P54311 ?   ?   'expression tag'        345  43 
4 8W8W GLY B 364 ? UNP P54311 ?   ?   'expression tag'        346  44 
4 8W8W GLY B 365 ? UNP P54311 ?   ?   'expression tag'        347  45 
4 8W8W SER B 366 ? UNP P54311 ?   ?   'expression tag'        348  46 
4 8W8W GLY B 367 ? UNP P54311 ?   ?   'expression tag'        349  47 
4 8W8W GLY B 368 ? UNP P54311 ?   ?   'expression tag'        350  48 
4 8W8W GLY B 369 ? UNP P54311 ?   ?   'expression tag'        351  49 
4 8W8W GLY B 370 ? UNP P54311 ?   ?   'expression tag'        352  50 
4 8W8W SER B 371 ? UNP P54311 ?   ?   'expression tag'        353  51 
4 8W8W SER B 372 ? UNP P54311 ?   ?   'expression tag'        354  52 
4 8W8W GLY B 373 ? UNP P54311 ?   ?   'expression tag'        355  53 
4 8W8W VAL B 374 ? UNP P54311 ?   ?   'expression tag'        356  54 
4 8W8W SER B 375 ? UNP P54311 ?   ?   'expression tag'        357  55 
4 8W8W GLY B 376 ? UNP P54311 ?   ?   'expression tag'        358  56 
4 8W8W TRP B 377 ? UNP P54311 ?   ?   'expression tag'        359  57 
4 8W8W ARG B 378 ? UNP P54311 ?   ?   'expression tag'        360  58 
4 8W8W LEU B 379 ? UNP P54311 ?   ?   'expression tag'        361  59 
4 8W8W PHE B 380 ? UNP P54311 ?   ?   'expression tag'        362  60 
4 8W8W LYS B 381 ? UNP P54311 ?   ?   'expression tag'        363  61 
4 8W8W LYS B 382 ? UNP P54311 ?   ?   'expression tag'        364  62 
4 8W8W ILE B 383 ? UNP P54311 ?   ?   'expression tag'        365  63 
4 8W8W SER B 384 ? UNP P54311 ?   ?   'expression tag'        366  64 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   hexameric 
_pdbx_struct_assembly.oligomeric_count     6 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 LYS A 162 ? ARG A 186 ? LYS R 41  ARG R 65  1 ? 25 
HELX_P HELX_P2  AA2 SER A 192 ? VAL A 222 ? SER R 71  VAL R 101 1 ? 31 
HELX_P HELX_P3  AA3 GLN A 232 ? TYR A 269 ? GLN R 111 TYR R 148 1 ? 38 
HELX_P HELX_P4  AA4 THR A 278 ? TYR A 303 ? THR R 157 TYR R 182 1 ? 26 
HELX_P HELX_P5  AA5 ILE A 310 ? ALA A 343 ? ILE R 189 ALA R 222 1 ? 34 
HELX_P HELX_P6  AA6 LYS A 360 ? CYS A 389 ? LYS R 239 CYS R 268 1 ? 30 
HELX_P HELX_P7  AA7 HIS A 401 ? TYR A 420 ? HIS R 280 TYR R 299 1 ? 20 
HELX_P HELX_P8  AA8 SER A 424 ? PHE A 431 ? SER R 303 PHE R 310 1 ? 8  
HELX_P HELX_P9  AA9 LEU B 22  ? CYS B 43  ? LEU B 4   CYS B 25  1 ? 22 
HELX_P HELX_P10 AB1 THR B 47  ? THR B 52  ? THR B 29  THR B 34  1 ? 6  
HELX_P HELX_P11 AB2 ILE C 9   ? ASN C 24  ? ILE G 9   ASN G 24  1 ? 16 
HELX_P HELX_P12 AB3 LYS C 29  ? HIS C 44  ? LYS G 29  HIS G 44  1 ? 16 
HELX_P HELX_P13 AB4 ALA C 45  ? ASP C 48  ? ALA G 45  ASP G 48  5 ? 4  
HELX_P HELX_P14 AB5 THR D 50  ? TYR D 54  ? THR N 28  TYR N 32  5 ? 5  
HELX_P HELX_P15 AB6 LYS D 109 ? THR D 113 ? LYS N 87  THR N 91  5 ? 5  
HELX_P HELX_P16 AB7 GLU F 16  ? ALA F 39  ? GLU A 16  ALA A 39  1 ? 24 
HELX_P HELX_P17 AB8 TRP F 220 ? PHE F 224 ? TRP A 234 PHE A 238 5 ? 5  
HELX_P HELX_P18 AB9 ARG F 251 ? ASN F 264 ? ARG A 265 ASN A 278 1 ? 14 
HELX_P HELX_P19 AC1 PHE F 298 ? TYR F 304 ? PHE A 312 TYR A 318 5 ? 7  
HELX_P HELX_P20 AC2 PRO F 318 ? THR F 336 ? PRO A 332 THR A 350 1 ? 19 
HELX_P HELX_P21 AC3 GLU F 356 ? TYR F 377 ? GLU A 370 TYR A 391 1 ? 22 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? D CYS 44  SG  ? ? ? 1_555 D CYS 118 SG ? ? N CYS 22  N CYS 96  1_555 ? ? ? ? ? ? ? 2.189 ? ? 
disulf2 disulf ? ? D CYS 121 SG  ? ? ? 1_555 D CYS 129 SG ? ? N CYS 99  N CYS 107 1_555 ? ? ? ? ? ? ? 1.896 ? ? 
metalc1 metalc ? ? A GLU 215 OE2 ? ? ? 1_555 G CA  .   CA ? ? R GLU 94  R CA  501 1_555 ? ? ? ? ? ? ? 2.882 ? ? 
metalc2 metalc ? ? A ASP 238 OD1 ? ? ? 1_555 G CA  .   CA ? ? R ASP 117 R CA  501 1_555 ? ? ? ? ? ? ? 2.341 ? ? 
metalc3 metalc ? ? A ASP 242 OD1 ? ? ? 1_555 G CA  .   CA ? ? R ASP 121 R CA  501 1_555 ? ? ? ? ? ? ? 2.737 ? ? 
metalc4 metalc ? ? A ASP 242 OD2 ? ? ? 1_555 G CA  .   CA ? ? R ASP 121 R CA  501 1_555 ? ? ? ? ? ? ? 2.255 ? ? 
metalc5 metalc ? ? G CA  .   CA  ? ? ? 1_555 E GLU 5   O  ? ? R CA  501 L GLU 5   1_555 ? ? ? ? ? ? ? 3.178 ? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
metalc ? ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  OE2 ? A GLU 215 ? R GLU 94  ? 1_555 CA ? G CA . ? R CA 501 ? 1_555 OD1 ? A ASP 238 ? R ASP 117 ? 1_555 81.8  ? 
2  OE2 ? A GLU 215 ? R GLU 94  ? 1_555 CA ? G CA . ? R CA 501 ? 1_555 OD1 ? A ASP 242 ? R ASP 121 ? 1_555 61.9  ? 
3  OD1 ? A ASP 238 ? R ASP 117 ? 1_555 CA ? G CA . ? R CA 501 ? 1_555 OD1 ? A ASP 242 ? R ASP 121 ? 1_555 92.6  ? 
4  OE2 ? A GLU 215 ? R GLU 94  ? 1_555 CA ? G CA . ? R CA 501 ? 1_555 OD2 ? A ASP 242 ? R ASP 121 ? 1_555 111.1 ? 
5  OD1 ? A ASP 238 ? R ASP 117 ? 1_555 CA ? G CA . ? R CA 501 ? 1_555 OD2 ? A ASP 242 ? R ASP 121 ? 1_555 87.3  ? 
6  OD1 ? A ASP 242 ? R ASP 121 ? 1_555 CA ? G CA . ? R CA 501 ? 1_555 OD2 ? A ASP 242 ? R ASP 121 ? 1_555 50.9  ? 
7  OE2 ? A GLU 215 ? R GLU 94  ? 1_555 CA ? G CA . ? R CA 501 ? 1_555 O   ? E GLU 5   ? L GLU 5   ? 1_555 55.4  ? 
8  OD1 ? A ASP 238 ? R ASP 117 ? 1_555 CA ? G CA . ? R CA 501 ? 1_555 O   ? E GLU 5   ? L GLU 5   ? 1_555 99.0  ? 
9  OD1 ? A ASP 242 ? R ASP 121 ? 1_555 CA ? G CA . ? R CA 501 ? 1_555 O   ? E GLU 5   ? L GLU 5   ? 1_555 113.2 ? 
10 OD2 ? A ASP 242 ? R ASP 121 ? 1_555 CA ? G CA . ? R CA 501 ? 1_555 O   ? E GLU 5   ? L GLU 5   ? 1_555 163.5 ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS D 44  ? CYS D 118 ? CYS N 22 ? 1_555 CYS N 96  ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS D 121 ? CYS D 129 ? CYS N 99 ? 1_555 CYS N 107 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 4 ? 
AA3 ? 4 ? 
AA4 ? 4 ? 
AA5 ? 4 ? 
AA6 ? 4 ? 
AA7 ? 4 ? 
AA8 ? 4 ? 
AA9 ? 6 ? 
AB1 ? 6 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA8 3 4 ? anti-parallel 
AA9 1 2 ? parallel      
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AA9 4 5 ? anti-parallel 
AA9 5 6 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? parallel      
AB1 3 4 ? parallel      
AB1 4 5 ? parallel      
AB1 5 6 ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ARG B 64  ? LEU B 69  ? ARG B 46  LEU B 51  
AA1 2 LEU B 354 ? ASN B 358 ? LEU B 336 ASN B 340 
AA1 3 VAL B 345 ? SER B 349 ? VAL B 327 SER B 331 
AA1 4 VAL B 333 ? VAL B 338 ? VAL B 315 VAL B 320 
AA2 1 ILE B 76  ? TRP B 81  ? ILE B 58  TRP B 63  
AA2 2 LEU B 87  ? SER B 92  ? LEU B 69  SER B 74  
AA2 3 LYS B 96  ? ASP B 101 ? LYS B 78  ASP B 83  
AA2 4 LYS B 107 ? PRO B 112 ? LYS B 89  PRO B 94  
AA3 1 VAL B 118 ? TYR B 123 ? VAL B 100 TYR B 105 
AA3 2 TYR B 129 ? GLY B 134 ? TYR B 111 GLY B 116 
AA3 3 CYS B 139 ? ASN B 143 ? CYS B 121 ASN B 125 
AA3 4 ARG B 152 ? LEU B 157 ? ARG B 134 LEU B 139 
AA4 1 LEU B 164 ? PHE B 169 ? LEU B 146 PHE B 151 
AA4 2 GLN B 174 ? SER B 179 ? GLN B 156 SER B 161 
AA4 3 CYS B 184 ? ASP B 188 ? CYS B 166 ASP B 170 
AA4 4 GLN B 193 ? PHE B 198 ? GLN B 175 PHE B 180 
AA5 1 VAL B 205 ? LEU B 210 ? VAL B 187 LEU B 192 
AA5 2 LEU B 216 ? ALA B 221 ? LEU B 198 ALA B 203 
AA5 3 ALA B 226 ? ASP B 230 ? ALA B 208 ASP B 212 
AA5 4 MET B 235 ? PHE B 240 ? MET B 217 PHE B 222 
AA6 1 ILE B 247 ? PHE B 252 ? ILE B 229 PHE B 234 
AA6 2 ALA B 258 ? SER B 263 ? ALA B 240 SER B 245 
AA6 3 CYS B 268 ? ASP B 272 ? CYS B 250 ASP B 254 
AA6 4 GLN B 277 ? TYR B 282 ? GLN B 259 TYR B 264 
AA7 1 ILE B 291 ? PHE B 296 ? ILE B 273 PHE B 278 
AA7 2 LEU B 302 ? TYR B 307 ? LEU B 284 TYR B 289 
AA7 3 CYS B 312 ? ASP B 316 ? CYS B 294 ASP B 298 
AA7 4 ARG B 322 ? LEU B 326 ? ARG B 304 LEU B 308 
AA8 1 GLN D 25  ? SER D 29  ? GLN N 3   SER N 7   
AA8 2 LEU D 40  ? SER D 47  ? LEU N 18  SER N 25  
AA8 3 THR D 100 ? MET D 105 ? THR N 78  MET N 83  
AA8 4 PHE D 90  ? ASP D 95  ? PHE N 68  ASP N 73  
AA9 1 GLY D 32  ? LEU D 33  ? GLY N 10  LEU N 11  
AA9 2 THR D 144 ? THR D 147 ? THR N 122 THR N 125 
AA9 3 ALA D 114 ? ARG D 120 ? ALA N 92  ARG N 98  
AA9 4 MET D 56  ? GLN D 61  ? MET N 34  GLN N 39  
AA9 5 LEU D 67  ? ILE D 73  ? LEU N 45  ILE N 51  
AA9 6 ILE D 80  ? TYR D 82  ? ILE N 58  TYR N 60  
AB1 1 GLU F 195 ? VAL F 200 ? GLU A 209 VAL A 214 
AB1 2 VAL F 203 ? PHE F 208 ? VAL A 217 PHE A 222 
AB1 3 HIS F 41  ? LEU F 44  ? HIS A 41  LEU A 44  
AB1 4 ALA F 229 ? VAL F 234 ? ALA A 243 VAL A 248 
AB1 5 SER F 272 ? LEU F 277 ? SER A 286 LEU A 291 
AB1 6 CYS F 345 ? PHE F 349 ? CYS A 359 PHE A 363 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N ARG B 66  ? N ARG B 48  O ILE B 356 ? O ILE B 338 
AA1 2 3 O TRP B 357 ? O TRP B 339 N VAL B 345 ? N VAL B 327 
AA1 3 4 O ALA B 346 ? O ALA B 328 N GLY B 337 ? N GLY B 319 
AA2 1 2 N ALA B 78  ? N ALA B 60  O ALA B 91  ? O ALA B 73  
AA2 2 3 N LEU B 88  ? N LEU B 70  O TRP B 100 ? O TRP B 82  
AA2 3 4 N ILE B 99  ? N ILE B 81  O VAL B 108 ? O VAL B 90  
AA3 1 2 N MET B 119 ? N MET B 101 O GLY B 133 ? O GLY B 115 
AA3 2 3 N VAL B 130 ? N VAL B 112 O TYR B 142 ? O TYR B 124 
AA3 3 4 N CYS B 139 ? N CYS B 121 O LEU B 157 ? O LEU B 139 
AA4 1 2 N SER B 165 ? N SER B 147 O SER B 178 ? O SER B 160 
AA4 2 3 N ILE B 175 ? N ILE B 157 O TRP B 187 ? O TRP B 169 
AA4 3 4 N LEU B 186 ? N LEU B 168 O THR B 195 ? O THR B 177 
AA5 1 2 N MET B 206 ? N MET B 188 O GLY B 220 ? O GLY B 202 
AA5 2 3 N PHE B 217 ? N PHE B 199 O TRP B 229 ? O TRP B 211 
AA5 3 4 N ALA B 226 ? N ALA B 208 O PHE B 240 ? O PHE B 222 
AA6 1 2 N ASN B 248 ? N ASN B 230 O GLY B 262 ? O GLY B 244 
AA6 2 3 N PHE B 259 ? N PHE B 241 O PHE B 271 ? O PHE B 253 
AA6 3 4 N LEU B 270 ? N LEU B 252 O LEU B 279 ? O LEU B 261 
AA7 1 2 N THR B 292 ? N THR B 274 O GLY B 306 ? O GLY B 288 
AA7 2 3 N ALA B 305 ? N ALA B 287 O ASN B 313 ? O ASN B 295 
AA7 3 4 N VAL B 314 ? N VAL B 296 O ALA B 323 ? O ALA B 305 
AA8 1 2 N SER D 29  ? N SER N 7   O SER D 43  ? O SER N 21  
AA8 2 3 N LEU D 40  ? N LEU N 18  O MET D 105 ? O MET N 83  
AA8 3 4 O GLN D 104 ? O GLN N 82  N THR D 91  ? N THR N 69  
AA9 1 2 N GLY D 32  ? N GLY N 10  O THR D 147 ? O THR N 125 
AA9 2 3 O THR D 144 ? O THR N 122 N TYR D 116 ? N TYR N 94  
AA9 3 4 O VAL D 115 ? O VAL N 93  N GLN D 61  ? N GLN N 39  
AA9 4 5 N ARG D 60  ? N ARG N 38  O GLU D 68  ? O GLU N 46  
AA9 5 6 N ASP D 72  ? N ASP N 50  O SER D 81  ? O SER N 59  
AB1 1 2 N PHE F 198 ? N PHE A 212 O PHE F 205 ? O PHE A 219 
AB1 2 3 O HIS F 206 ? O HIS A 220 N LEU F 43  ? N LEU A 43  
AB1 3 4 N LEU F 44  ? N LEU A 44  O ILE F 231 ? O ILE A 245 
AB1 4 5 N ILE F 230 ? N ILE A 244 O ILE F 274 ? O ILE A 288 
AB1 5 6 N LEU F 277 ? N LEU A 291 O HIS F 348 ? O HIS A 362 
# 
_pdbx_entry_details.entry_id                   8W8W 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_close_contact.id               1 
_pdbx_validate_close_contact.PDB_model_num    1 
_pdbx_validate_close_contact.auth_atom_id_1   OG 
_pdbx_validate_close_contact.auth_asym_id_1   B 
_pdbx_validate_close_contact.auth_comp_id_1   SER 
_pdbx_validate_close_contact.auth_seq_id_1    245 
_pdbx_validate_close_contact.PDB_ins_code_1   ? 
_pdbx_validate_close_contact.label_alt_id_1   ? 
_pdbx_validate_close_contact.auth_atom_id_2   OD1 
_pdbx_validate_close_contact.auth_asym_id_2   B 
_pdbx_validate_close_contact.auth_comp_id_2   ASP 
_pdbx_validate_close_contact.auth_seq_id_2    247 
_pdbx_validate_close_contact.PDB_ins_code_2   ? 
_pdbx_validate_close_contact.label_alt_id_2   ? 
_pdbx_validate_close_contact.dist             2.11 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 HIS R 102 ? ? -130.08 -38.22  
2  1 SER R 103 ? ? -131.31 -37.68  
3  1 TYR R 152 ? ? -67.76  -176.75 
4  1 HIS R 153 ? ? 62.19   -10.23  
5  1 SER R 185 ? ? -141.50 10.22   
6  1 ALA R 223 ? ? -94.63  53.07   
7  1 CYS R 268 ? ? -159.57 85.54   
8  1 THR R 278 ? ? -81.74  49.43   
9  1 THR B 34  ? ? -92.92  30.24   
10 1 ASN B 36  ? ? -99.74  35.33   
11 1 LEU B 117 ? ? -66.64  2.80    
12 1 LYS B 127 ? ? -93.20  55.00   
13 1 THR B 164 ? ? 70.18   33.73   
14 1 PHE B 292 ? ? 81.08   3.42    
15 1 PHE N 103 ? ? 68.16   -4.17   
16 1 GLU L 5   ? ? -129.84 -169.34 
17 1 TRP L 9   ? ? 82.66   27.13   
18 1 ALA A 48  ? ? -169.62 -168.33 
19 1 SER A 352 ? ? -140.88 42.50   
20 1 ASP A 354 ? ? 67.15   -0.54   
21 1 VAL A 367 ? ? -69.33  1.87    
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8W8W 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8W8W 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.9 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               107777 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               'MULTIPLE SOURCES' 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'The complex of alpha -MSH coupled MC3R-Gas' 
_em_entity_assembly.details              
;Cryo-EM structure of the agonist a-MSH bound to the active melanocortin-3 receptor (MC3R) in complex with the heterotrimeric Gs protein at 2.9 A resolution.
;
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1,2,3,4,5,6 
# 
_em_imaging.entry_id                        8W8W 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1200 
_em_imaging.nominal_defocus_max             1800 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8W8W 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8W8W 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 R ASP -120 ? A ASP 1   
2   1 Y 1 R TYR -119 ? A TYR 2   
3   1 Y 1 R LYS -118 ? A LYS 3   
4   1 Y 1 R ASP -117 ? A ASP 4   
5   1 Y 1 R ASP -116 ? A ASP 5   
6   1 Y 1 R ASP -115 ? A ASP 6   
7   1 Y 1 R ASP -114 ? A ASP 7   
8   1 Y 1 R LYS -113 ? A LYS 8   
9   1 Y 1 R GLY -112 ? A GLY 9   
10  1 Y 1 R SER -111 ? A SER 10  
11  1 Y 1 R ALA -110 ? A ALA 11  
12  1 Y 1 R ASP -109 ? A ASP 12  
13  1 Y 1 R LEU -108 ? A LEU 13  
14  1 Y 1 R GLU -107 ? A GLU 14  
15  1 Y 1 R ASP -106 ? A ASP 15  
16  1 Y 1 R ASN -105 ? A ASN 16  
17  1 Y 1 R TRP -104 ? A TRP 17  
18  1 Y 1 R GLU -103 ? A GLU 18  
19  1 Y 1 R THR -102 ? A THR 19  
20  1 Y 1 R LEU -101 ? A LEU 20  
21  1 Y 1 R ASN -100 ? A ASN 21  
22  1 Y 1 R ASP -99  ? A ASP 22  
23  1 Y 1 R ASN -98  ? A ASN 23  
24  1 Y 1 R LEU -97  ? A LEU 24  
25  1 Y 1 R LYS -96  ? A LYS 25  
26  1 Y 1 R VAL -95  ? A VAL 26  
27  1 Y 1 R ILE -94  ? A ILE 27  
28  1 Y 1 R GLU -93  ? A GLU 28  
29  1 Y 1 R LYS -92  ? A LYS 29  
30  1 Y 1 R ALA -91  ? A ALA 30  
31  1 Y 1 R ASP -90  ? A ASP 31  
32  1 Y 1 R ASN -89  ? A ASN 32  
33  1 Y 1 R ALA -88  ? A ALA 33  
34  1 Y 1 R ALA -87  ? A ALA 34  
35  1 Y 1 R GLN -86  ? A GLN 35  
36  1 Y 1 R VAL -85  ? A VAL 36  
37  1 Y 1 R LYS -84  ? A LYS 37  
38  1 Y 1 R ASP -83  ? A ASP 38  
39  1 Y 1 R ALA -82  ? A ALA 39  
40  1 Y 1 R LEU -81  ? A LEU 40  
41  1 Y 1 R THR -80  ? A THR 41  
42  1 Y 1 R LYS -79  ? A LYS 42  
43  1 Y 1 R MET -78  ? A MET 43  
44  1 Y 1 R ARG -77  ? A ARG 44  
45  1 Y 1 R ALA -76  ? A ALA 45  
46  1 Y 1 R ALA -75  ? A ALA 46  
47  1 Y 1 R ALA -74  ? A ALA 47  
48  1 Y 1 R LEU -73  ? A LEU 48  
49  1 Y 1 R ASP -72  ? A ASP 49  
50  1 Y 1 R ALA -71  ? A ALA 50  
51  1 Y 1 R GLN -70  ? A GLN 51  
52  1 Y 1 R LYS -69  ? A LYS 52  
53  1 Y 1 R ALA -68  ? A ALA 53  
54  1 Y 1 R THR -67  ? A THR 54  
55  1 Y 1 R PRO -66  ? A PRO 55  
56  1 Y 1 R PRO -65  ? A PRO 56  
57  1 Y 1 R LYS -64  ? A LYS 57  
58  1 Y 1 R LEU -63  ? A LEU 58  
59  1 Y 1 R GLU -62  ? A GLU 59  
60  1 Y 1 R ASP -61  ? A ASP 60  
61  1 Y 1 R LYS -60  ? A LYS 61  
62  1 Y 1 R SER -59  ? A SER 62  
63  1 Y 1 R PRO -58  ? A PRO 63  
64  1 Y 1 R ASP -57  ? A ASP 64  
65  1 Y 1 R SER -56  ? A SER 65  
66  1 Y 1 R PRO -55  ? A PRO 66  
67  1 Y 1 R GLU -54  ? A GLU 67  
68  1 Y 1 R MET -53  ? A MET 68  
69  1 Y 1 R LYS -52  ? A LYS 69  
70  1 Y 1 R ASP -51  ? A ASP 70  
71  1 Y 1 R PHE -50  ? A PHE 71  
72  1 Y 1 R ARG -49  ? A ARG 72  
73  1 Y 1 R HIS -48  ? A HIS 73  
74  1 Y 1 R GLY -47  ? A GLY 74  
75  1 Y 1 R PHE -46  ? A PHE 75  
76  1 Y 1 R ASP -45  ? A ASP 76  
77  1 Y 1 R ILE -44  ? A ILE 77  
78  1 Y 1 R LEU -43  ? A LEU 78  
79  1 Y 1 R VAL -42  ? A VAL 79  
80  1 Y 1 R GLY -41  ? A GLY 80  
81  1 Y 1 R GLN -40  ? A GLN 81  
82  1 Y 1 R ILE -39  ? A ILE 82  
83  1 Y 1 R ASP -38  ? A ASP 83  
84  1 Y 1 R ASP -37  ? A ASP 84  
85  1 Y 1 R ALA -36  ? A ALA 85  
86  1 Y 1 R LEU -35  ? A LEU 86  
87  1 Y 1 R LYS -34  ? A LYS 87  
88  1 Y 1 R LEU -33  ? A LEU 88  
89  1 Y 1 R ALA -32  ? A ALA 89  
90  1 Y 1 R ASN -31  ? A ASN 90  
91  1 Y 1 R GLU -30  ? A GLU 91  
92  1 Y 1 R GLY -29  ? A GLY 92  
93  1 Y 1 R LYS -28  ? A LYS 93  
94  1 Y 1 R VAL -27  ? A VAL 94  
95  1 Y 1 R LYS -26  ? A LYS 95  
96  1 Y 1 R GLU -25  ? A GLU 96  
97  1 Y 1 R ALA -24  ? A ALA 97  
98  1 Y 1 R GLN -23  ? A GLN 98  
99  1 Y 1 R ALA -22  ? A ALA 99  
100 1 Y 1 R ALA -21  ? A ALA 100 
101 1 Y 1 R ALA -20  ? A ALA 101 
102 1 Y 1 R GLU -19  ? A GLU 102 
103 1 Y 1 R GLN -18  ? A GLN 103 
104 1 Y 1 R LEU -17  ? A LEU 104 
105 1 Y 1 R LYS -16  ? A LYS 105 
106 1 Y 1 R THR -15  ? A THR 106 
107 1 Y 1 R THR -14  ? A THR 107 
108 1 Y 1 R ARG -13  ? A ARG 108 
109 1 Y 1 R ASN -12  ? A ASN 109 
110 1 Y 1 R ALA -11  ? A ALA 110 
111 1 Y 1 R TYR -10  ? A TYR 111 
112 1 Y 1 R ILE -9   ? A ILE 112 
113 1 Y 1 R GLN -8   ? A GLN 113 
114 1 Y 1 R LYS -7   ? A LYS 114 
115 1 Y 1 R TYR -6   ? A TYR 115 
116 1 Y 1 R LEU -5   ? A LEU 116 
117 1 Y 1 R LEU -4   ? A LEU 117 
118 1 Y 1 R VAL -3   ? A VAL 118 
119 1 Y 1 R PRO -2   ? A PRO 119 
120 1 Y 1 R ARG -1   ? A ARG 120 
121 1 Y 1 R GLY 0    ? A GLY 121 
122 1 Y 1 R SER 1    ? A SER 122 
123 1 Y 1 R ASN 2    ? A ASN 123 
124 1 Y 1 R ALA 3    ? A ALA 124 
125 1 Y 1 R SER 4    ? A SER 125 
126 1 Y 1 R CYS 5    ? A CYS 126 
127 1 Y 1 R CYS 6    ? A CYS 127 
128 1 Y 1 R LEU 7    ? A LEU 128 
129 1 Y 1 R PRO 8    ? A PRO 129 
130 1 Y 1 R SER 9    ? A SER 130 
131 1 Y 1 R VAL 10   ? A VAL 131 
132 1 Y 1 R GLN 11   ? A GLN 132 
133 1 Y 1 R PRO 12   ? A PRO 133 
134 1 Y 1 R THR 13   ? A THR 134 
135 1 Y 1 R LEU 14   ? A LEU 135 
136 1 Y 1 R PRO 15   ? A PRO 136 
137 1 Y 1 R ASN 16   ? A ASN 137 
138 1 Y 1 R GLY 17   ? A GLY 138 
139 1 Y 1 R SER 18   ? A SER 139 
140 1 Y 1 R GLU 19   ? A GLU 140 
141 1 Y 1 R HIS 20   ? A HIS 141 
142 1 Y 1 R LEU 21   ? A LEU 142 
143 1 Y 1 R GLN 22   ? A GLN 143 
144 1 Y 1 R ALA 23   ? A ALA 144 
145 1 Y 1 R PRO 24   ? A PRO 145 
146 1 Y 1 R PHE 25   ? A PHE 146 
147 1 Y 1 R PHE 26   ? A PHE 147 
148 1 Y 1 R SER 27   ? A SER 148 
149 1 Y 1 R ASN 28   ? A ASN 149 
150 1 Y 1 R GLN 29   ? A GLN 150 
151 1 Y 1 R SER 30   ? A SER 151 
152 1 Y 1 R SER 31   ? A SER 152 
153 1 Y 1 R SER 32   ? A SER 153 
154 1 Y 1 R ALA 33   ? A ALA 154 
155 1 Y 1 R PHE 34   ? A PHE 155 
156 1 Y 1 R CYS 35   ? A CYS 156 
157 1 Y 1 R GLU 36   ? A GLU 157 
158 1 Y 1 R GLN 37   ? A GLN 158 
159 1 Y 1 R PRO 225  ? A PRO 346 
160 1 Y 1 R PRO 226  ? A PRO 347 
161 1 Y 1 R ALA 227  ? A ALA 348 
162 1 Y 1 R ASP 228  ? A ASP 349 
163 1 Y 1 R GLY 229  ? A GLY 350 
164 1 Y 1 R VAL 230  ? A VAL 351 
165 1 Y 1 R ALA 231  ? A ALA 352 
166 1 Y 1 R PRO 232  ? A PRO 353 
167 1 Y 1 R GLN 233  ? A GLN 354 
168 1 Y 1 R GLN 234  ? A GLN 355 
169 1 Y 1 R HIS 235  ? A HIS 356 
170 1 Y 1 R SER 236  ? A SER 357 
171 1 Y 1 R CYS 237  ? A CYS 358 
172 1 Y 1 R ARG 311  ? A ARG 432 
173 1 Y 1 R GLU 312  ? A GLU 433 
174 1 Y 1 R ILE 313  ? A ILE 434 
175 1 Y 1 R LEU 314  ? A LEU 435 
176 1 Y 1 R CYS 315  ? A CYS 436 
177 1 Y 1 R GLY 316  ? A GLY 437 
178 1 Y 1 R CYS 317  ? A CYS 438 
179 1 Y 1 R ASN 318  ? A ASN 439 
180 1 Y 1 R GLY 319  ? A GLY 440 
181 1 Y 1 R MET 320  ? A MET 441 
182 1 Y 1 R ASN 321  ? A ASN 442 
183 1 Y 1 R LEU 322  ? A LEU 443 
184 1 Y 1 R GLY 323  ? A GLY 444 
185 1 Y 1 R VAL 324  ? A VAL 445 
186 1 Y 1 R PHE 325  ? A PHE 446 
187 1 Y 1 R THR 326  ? A THR 447 
188 1 Y 1 R LEU 327  ? A LEU 448 
189 1 Y 1 R GLU 328  ? A GLU 449 
190 1 Y 1 R ASP 329  ? A ASP 450 
191 1 Y 1 R PHE 330  ? A PHE 451 
192 1 Y 1 R VAL 331  ? A VAL 452 
193 1 Y 1 R GLY 332  ? A GLY 453 
194 1 Y 1 R ASP 333  ? A ASP 454 
195 1 Y 1 R TRP 334  ? A TRP 455 
196 1 Y 1 R GLU 335  ? A GLU 456 
197 1 Y 1 R GLN 336  ? A GLN 457 
198 1 Y 1 R THR 337  ? A THR 458 
199 1 Y 1 R ALA 338  ? A ALA 459 
200 1 Y 1 R ALA 339  ? A ALA 460 
201 1 Y 1 R TYR 340  ? A TYR 461 
202 1 Y 1 R ASN 341  ? A ASN 462 
203 1 Y 1 R LEU 342  ? A LEU 463 
204 1 Y 1 R ASP 343  ? A ASP 464 
205 1 Y 1 R GLN 344  ? A GLN 465 
206 1 Y 1 R VAL 345  ? A VAL 466 
207 1 Y 1 R LEU 346  ? A LEU 467 
208 1 Y 1 R GLU 347  ? A GLU 468 
209 1 Y 1 R GLN 348  ? A GLN 469 
210 1 Y 1 R GLY 349  ? A GLY 470 
211 1 Y 1 R GLY 350  ? A GLY 471 
212 1 Y 1 R VAL 351  ? A VAL 472 
213 1 Y 1 R SER 352  ? A SER 473 
214 1 Y 1 R SER 353  ? A SER 474 
215 1 Y 1 R LEU 354  ? A LEU 475 
216 1 Y 1 R LEU 355  ? A LEU 476 
217 1 Y 1 R GLN 356  ? A GLN 477 
218 1 Y 1 R ASN 357  ? A ASN 478 
219 1 Y 1 R LEU 358  ? A LEU 479 
220 1 Y 1 R ALA 359  ? A ALA 480 
221 1 Y 1 R VAL 360  ? A VAL 481 
222 1 Y 1 R SER 361  ? A SER 482 
223 1 Y 1 R VAL 362  ? A VAL 483 
224 1 Y 1 R THR 363  ? A THR 484 
225 1 Y 1 R PRO 364  ? A PRO 485 
226 1 Y 1 R ILE 365  ? A ILE 486 
227 1 Y 1 R GLN 366  ? A GLN 487 
228 1 Y 1 R ARG 367  ? A ARG 488 
229 1 Y 1 R ILE 368  ? A ILE 489 
230 1 Y 1 R VAL 369  ? A VAL 490 
231 1 Y 1 R ARG 370  ? A ARG 491 
232 1 Y 1 R SER 371  ? A SER 492 
233 1 Y 1 R GLY 372  ? A GLY 493 
234 1 Y 1 R GLU 373  ? A GLU 494 
235 1 Y 1 R ASN 374  ? A ASN 495 
236 1 Y 1 R ALA 375  ? A ALA 496 
237 1 Y 1 R LEU 376  ? A LEU 497 
238 1 Y 1 R LYS 377  ? A LYS 498 
239 1 Y 1 R ILE 378  ? A ILE 499 
240 1 Y 1 R ASP 379  ? A ASP 500 
241 1 Y 1 R ILE 380  ? A ILE 501 
242 1 Y 1 R HIS 381  ? A HIS 502 
243 1 Y 1 R VAL 382  ? A VAL 503 
244 1 Y 1 R ILE 383  ? A ILE 504 
245 1 Y 1 R ILE 384  ? A ILE 505 
246 1 Y 1 R PRO 385  ? A PRO 506 
247 1 Y 1 R TYR 386  ? A TYR 507 
248 1 Y 1 R GLU 387  ? A GLU 508 
249 1 Y 1 R GLY 388  ? A GLY 509 
250 1 Y 1 R LEU 389  ? A LEU 510 
251 1 Y 1 R SER 390  ? A SER 511 
252 1 Y 1 R ALA 391  ? A ALA 512 
253 1 Y 1 R ASP 392  ? A ASP 513 
254 1 Y 1 R GLN 393  ? A GLN 514 
255 1 Y 1 R MET 394  ? A MET 515 
256 1 Y 1 R ALA 395  ? A ALA 516 
257 1 Y 1 R GLN 396  ? A GLN 517 
258 1 Y 1 R ILE 397  ? A ILE 518 
259 1 Y 1 R GLU 398  ? A GLU 519 
260 1 Y 1 R GLU 399  ? A GLU 520 
261 1 Y 1 R VAL 400  ? A VAL 521 
262 1 Y 1 R PHE 401  ? A PHE 522 
263 1 Y 1 R LYS 402  ? A LYS 523 
264 1 Y 1 R VAL 403  ? A VAL 524 
265 1 Y 1 R VAL 404  ? A VAL 525 
266 1 Y 1 R TYR 405  ? A TYR 526 
267 1 Y 1 R PRO 406  ? A PRO 527 
268 1 Y 1 R VAL 407  ? A VAL 528 
269 1 Y 1 R ASP 408  ? A ASP 529 
270 1 Y 1 R ASP 409  ? A ASP 530 
271 1 Y 1 R HIS 410  ? A HIS 531 
272 1 Y 1 R HIS 411  ? A HIS 532 
273 1 Y 1 R PHE 412  ? A PHE 533 
274 1 Y 1 R LYS 413  ? A LYS 534 
275 1 Y 1 R VAL 414  ? A VAL 535 
276 1 Y 1 R ILE 415  ? A ILE 536 
277 1 Y 1 R LEU 416  ? A LEU 537 
278 1 Y 1 R PRO 417  ? A PRO 538 
279 1 Y 1 R TYR 418  ? A TYR 539 
280 1 Y 1 R GLY 419  ? A GLY 540 
281 1 Y 1 R THR 420  ? A THR 541 
282 1 Y 1 R LEU 421  ? A LEU 542 
283 1 Y 1 R VAL 422  ? A VAL 543 
284 1 Y 1 R ILE 423  ? A ILE 544 
285 1 Y 1 R ASP 424  ? A ASP 545 
286 1 Y 1 R GLY 425  ? A GLY 546 
287 1 Y 1 R VAL 426  ? A VAL 547 
288 1 Y 1 R THR 427  ? A THR 548 
289 1 Y 1 R PRO 428  ? A PRO 549 
290 1 Y 1 R ASN 429  ? A ASN 550 
291 1 Y 1 R MET 430  ? A MET 551 
292 1 Y 1 R LEU 431  ? A LEU 552 
293 1 Y 1 R ASN 432  ? A ASN 553 
294 1 Y 1 R TYR 433  ? A TYR 554 
295 1 Y 1 R PHE 434  ? A PHE 555 
296 1 Y 1 R GLY 435  ? A GLY 556 
297 1 Y 1 R ARG 436  ? A ARG 557 
298 1 Y 1 R PRO 437  ? A PRO 558 
299 1 Y 1 R TYR 438  ? A TYR 559 
300 1 Y 1 R GLU 439  ? A GLU 560 
301 1 Y 1 R GLY 440  ? A GLY 561 
302 1 Y 1 R ILE 441  ? A ILE 562 
303 1 Y 1 R ALA 442  ? A ALA 563 
304 1 Y 1 R VAL 443  ? A VAL 564 
305 1 Y 1 R PHE 444  ? A PHE 565 
306 1 Y 1 R ASP 445  ? A ASP 566 
307 1 Y 1 R GLY 446  ? A GLY 567 
308 1 Y 1 R LYS 447  ? A LYS 568 
309 1 Y 1 R LYS 448  ? A LYS 569 
310 1 Y 1 R ILE 449  ? A ILE 570 
311 1 Y 1 R THR 450  ? A THR 571 
312 1 Y 1 R VAL 451  ? A VAL 572 
313 1 Y 1 R THR 452  ? A THR 573 
314 1 Y 1 R GLY 453  ? A GLY 574 
315 1 Y 1 R THR 454  ? A THR 575 
316 1 Y 1 R LEU 455  ? A LEU 576 
317 1 Y 1 R TRP 456  ? A TRP 577 
318 1 Y 1 R ASN 457  ? A ASN 578 
319 1 Y 1 R GLY 458  ? A GLY 579 
320 1 Y 1 R ASN 459  ? A ASN 580 
321 1 Y 1 R LYS 460  ? A LYS 581 
322 1 Y 1 R ILE 461  ? A ILE 582 
323 1 Y 1 R ILE 462  ? A ILE 583 
324 1 Y 1 R ASP 463  ? A ASP 584 
325 1 Y 1 R GLU 464  ? A GLU 585 
326 1 Y 1 R ARG 465  ? A ARG 586 
327 1 Y 1 R LEU 466  ? A LEU 587 
328 1 Y 1 R ILE 467  ? A ILE 588 
329 1 Y 1 R THR 468  ? A THR 589 
330 1 Y 1 R PRO 469  ? A PRO 590 
331 1 Y 1 R ASP 470  ? A ASP 591 
332 1 Y 1 R GLY 471  ? A GLY 592 
333 1 Y 1 R SER 472  ? A SER 593 
334 1 Y 1 R MET 473  ? A MET 594 
335 1 Y 1 R LEU 474  ? A LEU 595 
336 1 Y 1 R PHE 475  ? A PHE 596 
337 1 Y 1 R ARG 476  ? A ARG 597 
338 1 Y 1 R VAL 477  ? A VAL 598 
339 1 Y 1 R THR 478  ? A THR 599 
340 1 Y 1 R ILE 479  ? A ILE 600 
341 1 Y 1 R ASN 480  ? A ASN 601 
342 1 Y 1 R SER 481  ? A SER 602 
343 1 Y 1 B MET -17  ? B MET 1   
344 1 Y 1 B HIS -16  ? B HIS 2   
345 1 Y 1 B HIS -15  ? B HIS 3   
346 1 Y 1 B HIS -14  ? B HIS 4   
347 1 Y 1 B HIS -13  ? B HIS 5   
348 1 Y 1 B HIS -12  ? B HIS 6   
349 1 Y 1 B HIS -11  ? B HIS 7   
350 1 Y 1 B LEU -10  ? B LEU 8   
351 1 Y 1 B GLU -9   ? B GLU 9   
352 1 Y 1 B VAL -8   ? B VAL 10  
353 1 Y 1 B LEU -7   ? B LEU 11  
354 1 Y 1 B PHE -6   ? B PHE 12  
355 1 Y 1 B GLN -5   ? B GLN 13  
356 1 Y 1 B GLY -4   ? B GLY 14  
357 1 Y 1 B PRO -3   ? B PRO 15  
358 1 Y 1 B GLY -2   ? B GLY 16  
359 1 Y 1 B SER -1   ? B SER 17  
360 1 Y 1 B SER 0    ? B SER 18  
361 1 Y 1 B GLY 1    ? B GLY 19  
362 1 Y 1 B SER 2    ? B SER 20  
363 1 Y 1 B GLY 341  ? B GLY 359 
364 1 Y 1 B SER 342  ? B SER 360 
365 1 Y 1 B SER 343  ? B SER 361 
366 1 Y 1 B GLY 344  ? B GLY 362 
367 1 Y 1 B GLY 345  ? B GLY 363 
368 1 Y 1 B GLY 346  ? B GLY 364 
369 1 Y 1 B GLY 347  ? B GLY 365 
370 1 Y 1 B SER 348  ? B SER 366 
371 1 Y 1 B GLY 349  ? B GLY 367 
372 1 Y 1 B GLY 350  ? B GLY 368 
373 1 Y 1 B GLY 351  ? B GLY 369 
374 1 Y 1 B GLY 352  ? B GLY 370 
375 1 Y 1 B SER 353  ? B SER 371 
376 1 Y 1 B SER 354  ? B SER 372 
377 1 Y 1 B GLY 355  ? B GLY 373 
378 1 Y 1 B VAL 356  ? B VAL 374 
379 1 Y 1 B SER 357  ? B SER 375 
380 1 Y 1 B GLY 358  ? B GLY 376 
381 1 Y 1 B TRP 359  ? B TRP 377 
382 1 Y 1 B ARG 360  ? B ARG 378 
383 1 Y 1 B LEU 361  ? B LEU 379 
384 1 Y 1 B PHE 362  ? B PHE 380 
385 1 Y 1 B LYS 363  ? B LYS 381 
386 1 Y 1 B LYS 364  ? B LYS 382 
387 1 Y 1 B ILE 365  ? B ILE 383 
388 1 Y 1 B SER 366  ? B SER 384 
389 1 Y 1 G MET 1    ? C MET 1   
390 1 Y 1 G ALA 2    ? C ALA 2   
391 1 Y 1 G SER 3    ? C SER 3   
392 1 Y 1 G ASN 4    ? C ASN 4   
393 1 Y 1 G ASN 5    ? C ASN 5   
394 1 Y 1 G GLU 63   ? C GLU 63  
395 1 Y 1 G LYS 64   ? C LYS 64  
396 1 Y 1 G LYS 65   ? C LYS 65  
397 1 Y 1 G PHE 66   ? C PHE 66  
398 1 Y 1 G PHE 67   ? C PHE 67  
399 1 Y 1 G CYS 68   ? C CYS 68  
400 1 Y 1 G ALA 69   ? C ALA 69  
401 1 Y 1 G ILE 70   ? C ILE 70  
402 1 Y 1 G LEU 71   ? C LEU 71  
403 1 Y 1 N MET -21  ? D MET 1   
404 1 Y 1 N LYS -20  ? D LYS 2   
405 1 Y 1 N TYR -19  ? D TYR 3   
406 1 Y 1 N LEU -18  ? D LEU 4   
407 1 Y 1 N LEU -17  ? D LEU 5   
408 1 Y 1 N PRO -16  ? D PRO 6   
409 1 Y 1 N THR -15  ? D THR 7   
410 1 Y 1 N ALA -14  ? D ALA 8   
411 1 Y 1 N ALA -13  ? D ALA 9   
412 1 Y 1 N ALA -12  ? D ALA 10  
413 1 Y 1 N GLY -11  ? D GLY 11  
414 1 Y 1 N LEU -10  ? D LEU 12  
415 1 Y 1 N LEU -9   ? D LEU 13  
416 1 Y 1 N LEU -8   ? D LEU 14  
417 1 Y 1 N LEU -7   ? D LEU 15  
418 1 Y 1 N ALA -6   ? D ALA 16  
419 1 Y 1 N ALA -5   ? D ALA 17  
420 1 Y 1 N GLN -4   ? D GLN 18  
421 1 Y 1 N PRO -3   ? D PRO 19  
422 1 Y 1 N ALA -2   ? D ALA 20  
423 1 Y 1 N MET -1   ? D MET 21  
424 1 Y 1 N ALA 0    ? D ALA 22  
425 1 Y 1 N SER 127  ? D SER 149 
426 1 Y 1 N SER 128  ? D SER 150 
427 1 Y 1 N HIS 129  ? D HIS 151 
428 1 Y 1 N HIS 130  ? D HIS 152 
429 1 Y 1 N HIS 131  ? D HIS 153 
430 1 Y 1 N HIS 132  ? D HIS 154 
431 1 Y 1 N HIS 133  ? D HIS 155 
432 1 Y 1 N HIS 134  ? D HIS 156 
433 1 Y 1 N GLU 135  ? D GLU 157 
434 1 Y 1 N PRO 136  ? D PRO 158 
435 1 Y 1 N GLU 137  ? D GLU 159 
436 1 Y 1 N ALA 138  ? D ALA 160 
437 1 Y 1 A MET 1    ? F MET 1   
438 1 Y 1 A GLY 2    ? F GLY 2   
439 1 Y 1 A CYS 3    ? F CYS 3   
440 1 Y 1 A LEU 4    ? F LEU 4   
441 1 Y 1 A GLY 5    ? F GLY 5   
442 1 Y 1 A ASN 6    ? F ASN 6   
443 1 Y 1 A SER 7    ? F SER 7   
444 1 Y 1 A LYS 8    ? F LYS 8   
445 1 Y 1 A THR 9    ? F THR 9   
446 1 Y 1 A GLU 10   ? F GLU 10  
447 1 Y 1 A ASP 11   ? F ASP 11  
448 1 Y 1 A GLN 12   ? F GLN 12  
449 1 Y 1 A ARG 13   ? F ARG 13  
450 1 Y 1 A ASN 14   ? F ASN 14  
451 1 Y 1 A GLU 64   ? F GLU 50  
452 1 Y 1 A SER 65   ? F SER 51  
453 1 Y 1 A GLY 66   ? F GLY 52  
454 1 Y 1 A LYS 67   ? F LYS 53  
455 1 Y 1 A SER 68   ? F SER 54  
456 1 Y 1 A THR 69   ? F THR 55  
457 1 Y 1 A ILE 70   ? F ILE 56  
458 1 Y 1 A VAL 71   ? F VAL 57  
459 1 Y 1 A LYS 72   ? F LYS 58  
460 1 Y 1 A GLN 73   ? F GLN 59  
461 1 Y 1 A MET 74   ? F MET 60  
462 1 Y 1 A ARG 75   ? F ARG 61  
463 1 Y 1 A ILE 76   ? F ILE 62  
464 1 Y 1 A LEU 77   ? F LEU 63  
465 1 Y 1 A HIS 78   ? F HIS 64  
466 1 Y 1 A VAL 79   ? F VAL 65  
467 1 Y 1 A ASN 80   ? F ASN 66  
468 1 Y 1 A GLY 81   ? F GLY 67  
469 1 Y 1 A PHE 82   ? F PHE 68  
470 1 Y 1 A ASN 83   ? F ASN 69  
471 1 Y 1 A GLY 84   ? F GLY 70  
472 1 Y 1 A ASP 85   ? F ASP 71  
473 1 Y 1 A SER 86   ? F SER 72  
474 1 Y 1 A GLU 87   ? F GLU 73  
475 1 Y 1 A LYS 88   ? F LYS 74  
476 1 Y 1 A ALA 89   ? F ALA 75  
477 1 Y 1 A THR 90   ? F THR 76  
478 1 Y 1 A LYS 91   ? F LYS 77  
479 1 Y 1 A VAL 92   ? F VAL 78  
480 1 Y 1 A GLN 93   ? F GLN 79  
481 1 Y 1 A ASP 94   ? F ASP 80  
482 1 Y 1 A ILE 95   ? F ILE 81  
483 1 Y 1 A LYS 96   ? F LYS 82  
484 1 Y 1 A ASN 97   ? F ASN 83  
485 1 Y 1 A ASN 98   ? F ASN 84  
486 1 Y 1 A LEU 99   ? F LEU 85  
487 1 Y 1 A LYS 100  ? F LYS 86  
488 1 Y 1 A GLU 101  ? F GLU 87  
489 1 Y 1 A ALA 102  ? F ALA 88  
490 1 Y 1 A ILE 103  ? F ILE 89  
491 1 Y 1 A GLU 104  ? F GLU 90  
492 1 Y 1 A THR 105  ? F THR 91  
493 1 Y 1 A ILE 106  ? F ILE 92  
494 1 Y 1 A VAL 107  ? F VAL 93  
495 1 Y 1 A ALA 108  ? F ALA 94  
496 1 Y 1 A ALA 109  ? F ALA 95  
497 1 Y 1 A MET 110  ? F MET 96  
498 1 Y 1 A SER 111  ? F SER 97  
499 1 Y 1 A ASN 112  ? F ASN 98  
500 1 Y 1 A LEU 113  ? F LEU 99  
501 1 Y 1 A VAL 114  ? F VAL 100 
502 1 Y 1 A PRO 115  ? F PRO 101 
503 1 Y 1 A PRO 116  ? F PRO 102 
504 1 Y 1 A VAL 117  ? F VAL 103 
505 1 Y 1 A GLU 118  ? F GLU 104 
506 1 Y 1 A LEU 119  ? F LEU 105 
507 1 Y 1 A ALA 120  ? F ALA 106 
508 1 Y 1 A ASN 121  ? F ASN 107 
509 1 Y 1 A PRO 122  ? F PRO 108 
510 1 Y 1 A GLU 123  ? F GLU 109 
511 1 Y 1 A ASN 124  ? F ASN 110 
512 1 Y 1 A GLN 125  ? F GLN 111 
513 1 Y 1 A PHE 126  ? F PHE 112 
514 1 Y 1 A ARG 127  ? F ARG 113 
515 1 Y 1 A VAL 128  ? F VAL 114 
516 1 Y 1 A ASP 129  ? F ASP 115 
517 1 Y 1 A TYR 130  ? F TYR 116 
518 1 Y 1 A ILE 131  ? F ILE 117 
519 1 Y 1 A LEU 132  ? F LEU 118 
520 1 Y 1 A SER 133  ? F SER 119 
521 1 Y 1 A VAL 134  ? F VAL 120 
522 1 Y 1 A MET 135  ? F MET 121 
523 1 Y 1 A ASN 136  ? F ASN 122 
524 1 Y 1 A VAL 137  ? F VAL 123 
525 1 Y 1 A PRO 138  ? F PRO 124 
526 1 Y 1 A ASP 139  ? F ASP 125 
527 1 Y 1 A PHE 140  ? F PHE 126 
528 1 Y 1 A ASP 141  ? F ASP 127 
529 1 Y 1 A PHE 142  ? F PHE 128 
530 1 Y 1 A PRO 143  ? F PRO 129 
531 1 Y 1 A PRO 144  ? F PRO 130 
532 1 Y 1 A GLU 145  ? F GLU 131 
533 1 Y 1 A PHE 146  ? F PHE 132 
534 1 Y 1 A TYR 147  ? F TYR 133 
535 1 Y 1 A GLU 148  ? F GLU 134 
536 1 Y 1 A HIS 149  ? F HIS 135 
537 1 Y 1 A ALA 150  ? F ALA 136 
538 1 Y 1 A LYS 151  ? F LYS 137 
539 1 Y 1 A ALA 152  ? F ALA 138 
540 1 Y 1 A LEU 153  ? F LEU 139 
541 1 Y 1 A TRP 154  ? F TRP 140 
542 1 Y 1 A GLU 155  ? F GLU 141 
543 1 Y 1 A ASP 156  ? F ASP 142 
544 1 Y 1 A GLU 157  ? F GLU 143 
545 1 Y 1 A GLY 158  ? F GLY 144 
546 1 Y 1 A VAL 159  ? F VAL 145 
547 1 Y 1 A ARG 160  ? F ARG 146 
548 1 Y 1 A ALA 161  ? F ALA 147 
549 1 Y 1 A CYS 162  ? F CYS 148 
550 1 Y 1 A TYR 163  ? F TYR 149 
551 1 Y 1 A GLU 164  ? F GLU 150 
552 1 Y 1 A ARG 165  ? F ARG 151 
553 1 Y 1 A SER 166  ? F SER 152 
554 1 Y 1 A ASN 167  ? F ASN 153 
555 1 Y 1 A GLU 168  ? F GLU 154 
556 1 Y 1 A TYR 169  ? F TYR 155 
557 1 Y 1 A GLN 170  ? F GLN 156 
558 1 Y 1 A LEU 171  ? F LEU 157 
559 1 Y 1 A ILE 172  ? F ILE 158 
560 1 Y 1 A ASP 173  ? F ASP 159 
561 1 Y 1 A CYS 174  ? F CYS 160 
562 1 Y 1 A ALA 175  ? F ALA 161 
563 1 Y 1 A GLN 176  ? F GLN 162 
564 1 Y 1 A TYR 177  ? F TYR 163 
565 1 Y 1 A PHE 178  ? F PHE 164 
566 1 Y 1 A LEU 179  ? F LEU 165 
567 1 Y 1 A ASP 180  ? F ASP 166 
568 1 Y 1 A LYS 181  ? F LYS 167 
569 1 Y 1 A ILE 182  ? F ILE 168 
570 1 Y 1 A ASP 183  ? F ASP 169 
571 1 Y 1 A VAL 184  ? F VAL 170 
572 1 Y 1 A ILE 185  ? F ILE 171 
573 1 Y 1 A LYS 186  ? F LYS 172 
574 1 Y 1 A GLN 187  ? F GLN 173 
575 1 Y 1 A ALA 188  ? F ALA 174 
576 1 Y 1 A ASP 189  ? F ASP 175 
577 1 Y 1 A TYR 190  ? F TYR 176 
578 1 Y 1 A VAL 191  ? F VAL 177 
579 1 Y 1 A PRO 192  ? F PRO 178 
580 1 Y 1 A SER 193  ? F SER 179 
581 1 Y 1 A ASP 194  ? F ASP 180 
582 1 Y 1 A GLN 195  ? F GLN 181 
583 1 Y 1 A ASP 196  ? F ASP 182 
584 1 Y 1 A LEU 197  ? F LEU 183 
585 1 Y 1 A LEU 198  ? F LEU 184 
586 1 Y 1 A ARG 199  ? F ARG 185 
587 1 Y 1 A CYS 200  ? F CYS 186 
588 1 Y 1 A ARG 201  ? F ARG 187 
589 1 Y 1 A VAL 202  ? F VAL 188 
590 1 Y 1 A LEU 203  ? F LEU 189 
591 1 Y 1 A THR 204  ? F THR 190 
592 1 Y 1 A SER 205  ? F SER 191 
593 1 Y 1 A GLY 206  ? F GLY 192 
594 1 Y 1 A ILE 207  ? F ILE 193 
595 1 Y 1 A SER 250  ? F SER 236 
596 1 Y 1 A SER 251  ? F SER 237 
597 1 Y 1 A SER 252  ? F SER 238 
598 1 Y 1 A TYR 253  ? F TYR 239 
599 1 Y 1 A ASN 254  ? F ASN 240 
600 1 Y 1 A MET 255  ? F MET 241 
601 1 Y 1 A VAL 256  ? F VAL 242 
602 1 Y 1 A ILE 257  ? F ILE 243 
603 1 Y 1 A ARG 258  ? F ARG 244 
604 1 Y 1 A GLU 259  ? F GLU 245 
605 1 Y 1 A ASP 260  ? F ASP 246 
606 1 Y 1 A ASN 261  ? F ASN 247 
607 1 Y 1 A GLN 262  ? F GLN 248 
608 1 Y 1 A THR 263  ? F THR 249 
609 1 Y 1 A ASP 295  ? F ASP 281 
610 1 Y 1 A LEU 296  ? F LEU 282 
611 1 Y 1 A LEU 297  ? F LEU 283 
612 1 Y 1 A ALA 298  ? F ALA 284 
613 1 Y 1 A GLU 299  ? F GLU 285 
614 1 Y 1 A LYS 300  ? F LYS 286 
615 1 Y 1 A VAL 301  ? F VAL 287 
616 1 Y 1 A LEU 302  ? F LEU 288 
617 1 Y 1 A ALA 303  ? F ALA 289 
618 1 Y 1 A GLY 304  ? F GLY 290 
619 1 Y 1 A LYS 305  ? F LYS 291 
620 1 Y 1 A SER 306  ? F SER 292 
621 1 Y 1 A LYS 307  ? F LYS 293 
622 1 Y 1 A PRO 321  ? F PRO 307 
623 1 Y 1 A GLU 322  ? F GLU 308 
624 1 Y 1 A ASP 323  ? F ASP 309 
625 1 Y 1 A ALA 324  ? F ALA 310 
626 1 Y 1 A THR 325  ? F THR 311 
627 1 Y 1 A PRO 326  ? F PRO 312 
628 1 Y 1 A GLU 327  ? F GLU 313 
629 1 Y 1 A PRO 328  ? F PRO 314 
630 1 Y 1 A GLY 329  ? F GLY 315 
631 1 Y 1 A GLU 330  ? F GLU 316 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CA  CA   CA N N 74  
CYS N    N  N N 75  
CYS CA   C  N R 76  
CYS C    C  N N 77  
CYS O    O  N N 78  
CYS CB   C  N N 79  
CYS SG   S  N N 80  
CYS OXT  O  N N 81  
CYS H    H  N N 82  
CYS H2   H  N N 83  
CYS HA   H  N N 84  
CYS HB2  H  N N 85  
CYS HB3  H  N N 86  
CYS HG   H  N N 87  
CYS HXT  H  N N 88  
GLN N    N  N N 89  
GLN CA   C  N S 90  
GLN C    C  N N 91  
GLN O    O  N N 92  
GLN CB   C  N N 93  
GLN CG   C  N N 94  
GLN CD   C  N N 95  
GLN OE1  O  N N 96  
GLN NE2  N  N N 97  
GLN OXT  O  N N 98  
GLN H    H  N N 99  
GLN H2   H  N N 100 
GLN HA   H  N N 101 
GLN HB2  H  N N 102 
GLN HB3  H  N N 103 
GLN HG2  H  N N 104 
GLN HG3  H  N N 105 
GLN HE21 H  N N 106 
GLN HE22 H  N N 107 
GLN HXT  H  N N 108 
GLU N    N  N N 109 
GLU CA   C  N S 110 
GLU C    C  N N 111 
GLU O    O  N N 112 
GLU CB   C  N N 113 
GLU CG   C  N N 114 
GLU CD   C  N N 115 
GLU OE1  O  N N 116 
GLU OE2  O  N N 117 
GLU OXT  O  N N 118 
GLU H    H  N N 119 
GLU H2   H  N N 120 
GLU HA   H  N N 121 
GLU HB2  H  N N 122 
GLU HB3  H  N N 123 
GLU HG2  H  N N 124 
GLU HG3  H  N N 125 
GLU HE2  H  N N 126 
GLU HXT  H  N N 127 
GLY N    N  N N 128 
GLY CA   C  N N 129 
GLY C    C  N N 130 
GLY O    O  N N 131 
GLY OXT  O  N N 132 
GLY H    H  N N 133 
GLY H2   H  N N 134 
GLY HA2  H  N N 135 
GLY HA3  H  N N 136 
GLY HXT  H  N N 137 
HIS N    N  N N 138 
HIS CA   C  N S 139 
HIS C    C  N N 140 
HIS O    O  N N 141 
HIS CB   C  N N 142 
HIS CG   C  Y N 143 
HIS ND1  N  Y N 144 
HIS CD2  C  Y N 145 
HIS CE1  C  Y N 146 
HIS NE2  N  Y N 147 
HIS OXT  O  N N 148 
HIS H    H  N N 149 
HIS H2   H  N N 150 
HIS HA   H  N N 151 
HIS HB2  H  N N 152 
HIS HB3  H  N N 153 
HIS HD1  H  N N 154 
HIS HD2  H  N N 155 
HIS HE1  H  N N 156 
HIS HE2  H  N N 157 
HIS HXT  H  N N 158 
ILE N    N  N N 159 
ILE CA   C  N S 160 
ILE C    C  N N 161 
ILE O    O  N N 162 
ILE CB   C  N S 163 
ILE CG1  C  N N 164 
ILE CG2  C  N N 165 
ILE CD1  C  N N 166 
ILE OXT  O  N N 167 
ILE H    H  N N 168 
ILE H2   H  N N 169 
ILE HA   H  N N 170 
ILE HB   H  N N 171 
ILE HG12 H  N N 172 
ILE HG13 H  N N 173 
ILE HG21 H  N N 174 
ILE HG22 H  N N 175 
ILE HG23 H  N N 176 
ILE HD11 H  N N 177 
ILE HD12 H  N N 178 
ILE HD13 H  N N 179 
ILE HXT  H  N N 180 
LEU N    N  N N 181 
LEU CA   C  N S 182 
LEU C    C  N N 183 
LEU O    O  N N 184 
LEU CB   C  N N 185 
LEU CG   C  N N 186 
LEU CD1  C  N N 187 
LEU CD2  C  N N 188 
LEU OXT  O  N N 189 
LEU H    H  N N 190 
LEU H2   H  N N 191 
LEU HA   H  N N 192 
LEU HB2  H  N N 193 
LEU HB3  H  N N 194 
LEU HG   H  N N 195 
LEU HD11 H  N N 196 
LEU HD12 H  N N 197 
LEU HD13 H  N N 198 
LEU HD21 H  N N 199 
LEU HD22 H  N N 200 
LEU HD23 H  N N 201 
LEU HXT  H  N N 202 
LYS N    N  N N 203 
LYS CA   C  N S 204 
LYS C    C  N N 205 
LYS O    O  N N 206 
LYS CB   C  N N 207 
LYS CG   C  N N 208 
LYS CD   C  N N 209 
LYS CE   C  N N 210 
LYS NZ   N  N N 211 
LYS OXT  O  N N 212 
LYS H    H  N N 213 
LYS H2   H  N N 214 
LYS HA   H  N N 215 
LYS HB2  H  N N 216 
LYS HB3  H  N N 217 
LYS HG2  H  N N 218 
LYS HG3  H  N N 219 
LYS HD2  H  N N 220 
LYS HD3  H  N N 221 
LYS HE2  H  N N 222 
LYS HE3  H  N N 223 
LYS HZ1  H  N N 224 
LYS HZ2  H  N N 225 
LYS HZ3  H  N N 226 
LYS HXT  H  N N 227 
MET N    N  N N 228 
MET CA   C  N S 229 
MET C    C  N N 230 
MET O    O  N N 231 
MET CB   C  N N 232 
MET CG   C  N N 233 
MET SD   S  N N 234 
MET CE   C  N N 235 
MET OXT  O  N N 236 
MET H    H  N N 237 
MET H2   H  N N 238 
MET HA   H  N N 239 
MET HB2  H  N N 240 
MET HB3  H  N N 241 
MET HG2  H  N N 242 
MET HG3  H  N N 243 
MET HE1  H  N N 244 
MET HE2  H  N N 245 
MET HE3  H  N N 246 
MET HXT  H  N N 247 
PHE N    N  N N 248 
PHE CA   C  N S 249 
PHE C    C  N N 250 
PHE O    O  N N 251 
PHE CB   C  N N 252 
PHE CG   C  Y N 253 
PHE CD1  C  Y N 254 
PHE CD2  C  Y N 255 
PHE CE1  C  Y N 256 
PHE CE2  C  Y N 257 
PHE CZ   C  Y N 258 
PHE OXT  O  N N 259 
PHE H    H  N N 260 
PHE H2   H  N N 261 
PHE HA   H  N N 262 
PHE HB2  H  N N 263 
PHE HB3  H  N N 264 
PHE HD1  H  N N 265 
PHE HD2  H  N N 266 
PHE HE1  H  N N 267 
PHE HE2  H  N N 268 
PHE HZ   H  N N 269 
PHE HXT  H  N N 270 
PRO N    N  N N 271 
PRO CA   C  N S 272 
PRO C    C  N N 273 
PRO O    O  N N 274 
PRO CB   C  N N 275 
PRO CG   C  N N 276 
PRO CD   C  N N 277 
PRO OXT  O  N N 278 
PRO H    H  N N 279 
PRO HA   H  N N 280 
PRO HB2  H  N N 281 
PRO HB3  H  N N 282 
PRO HG2  H  N N 283 
PRO HG3  H  N N 284 
PRO HD2  H  N N 285 
PRO HD3  H  N N 286 
PRO HXT  H  N N 287 
SER N    N  N N 288 
SER CA   C  N S 289 
SER C    C  N N 290 
SER O    O  N N 291 
SER CB   C  N N 292 
SER OG   O  N N 293 
SER OXT  O  N N 294 
SER H    H  N N 295 
SER H2   H  N N 296 
SER HA   H  N N 297 
SER HB2  H  N N 298 
SER HB3  H  N N 299 
SER HG   H  N N 300 
SER HXT  H  N N 301 
THR N    N  N N 302 
THR CA   C  N S 303 
THR C    C  N N 304 
THR O    O  N N 305 
THR CB   C  N R 306 
THR OG1  O  N N 307 
THR CG2  C  N N 308 
THR OXT  O  N N 309 
THR H    H  N N 310 
THR H2   H  N N 311 
THR HA   H  N N 312 
THR HB   H  N N 313 
THR HG1  H  N N 314 
THR HG21 H  N N 315 
THR HG22 H  N N 316 
THR HG23 H  N N 317 
THR HXT  H  N N 318 
TRP N    N  N N 319 
TRP CA   C  N S 320 
TRP C    C  N N 321 
TRP O    O  N N 322 
TRP CB   C  N N 323 
TRP CG   C  Y N 324 
TRP CD1  C  Y N 325 
TRP CD2  C  Y N 326 
TRP NE1  N  Y N 327 
TRP CE2  C  Y N 328 
TRP CE3  C  Y N 329 
TRP CZ2  C  Y N 330 
TRP CZ3  C  Y N 331 
TRP CH2  C  Y N 332 
TRP OXT  O  N N 333 
TRP H    H  N N 334 
TRP H2   H  N N 335 
TRP HA   H  N N 336 
TRP HB2  H  N N 337 
TRP HB3  H  N N 338 
TRP HD1  H  N N 339 
TRP HE1  H  N N 340 
TRP HE3  H  N N 341 
TRP HZ2  H  N N 342 
TRP HZ3  H  N N 343 
TRP HH2  H  N N 344 
TRP HXT  H  N N 345 
TYR N    N  N N 346 
TYR CA   C  N S 347 
TYR C    C  N N 348 
TYR O    O  N N 349 
TYR CB   C  N N 350 
TYR CG   C  Y N 351 
TYR CD1  C  Y N 352 
TYR CD2  C  Y N 353 
TYR CE1  C  Y N 354 
TYR CE2  C  Y N 355 
TYR CZ   C  Y N 356 
TYR OH   O  N N 357 
TYR OXT  O  N N 358 
TYR H    H  N N 359 
TYR H2   H  N N 360 
TYR HA   H  N N 361 
TYR HB2  H  N N 362 
TYR HB3  H  N N 363 
TYR HD1  H  N N 364 
TYR HD2  H  N N 365 
TYR HE1  H  N N 366 
TYR HE2  H  N N 367 
TYR HH   H  N N 368 
TYR HXT  H  N N 369 
VAL N    N  N N 370 
VAL CA   C  N S 371 
VAL C    C  N N 372 
VAL O    O  N N 373 
VAL CB   C  N N 374 
VAL CG1  C  N N 375 
VAL CG2  C  N N 376 
VAL OXT  O  N N 377 
VAL H    H  N N 378 
VAL H2   H  N N 379 
VAL HA   H  N N 380 
VAL HB   H  N N 381 
VAL HG11 H  N N 382 
VAL HG12 H  N N 383 
VAL HG13 H  N N 384 
VAL HG21 H  N N 385 
VAL HG22 H  N N 386 
VAL HG23 H  N N 387 
VAL HXT  H  N N 388 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-09-04 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8W8W 
_em_admin.last_update        2025-03-19 
_em_admin.map_release_date   2025-03-19 
_em_admin.title              'Cryo-EM structure of alpha-MSH-MC3R-Gs_Nb35 complex' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          7108 
_em_entity_assembly_recombinant.organism             'Spodoptera frugiperda' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_entity_assembly_synthetic.cell                 ? 
_em_entity_assembly_synthetic.cellular_location    ? 
_em_entity_assembly_synthetic.entity_assembly_id   1 
_em_entity_assembly_synthetic.id                   1 
_em_entity_assembly_synthetic.ncbi_tax_id          9606 
_em_entity_assembly_synthetic.organ                ? 
_em_entity_assembly_synthetic.organelle            ? 
_em_entity_assembly_synthetic.organism             'Homo sapiens' 
_em_entity_assembly_synthetic.strain               ? 
_em_entity_assembly_synthetic.tissue               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         1 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'MODEL REFINEMENT'              ? 1  ? ? ? PHENIX 1.20.1_4487: 
'IMAGE ACQUISITION'             ? 2  1 1 1 ?      ?            
'PARTICLE SELECTION'            ? 3  1 1 1 ?      ?            
'VOLUME SELECTION'              ? 4  1 1 1 ?      ?            
CLASSIFICATION                  ? 5  1 1 1 ?      ?            
MASKING                         ? 6  1 1 1 ?      ?            
RECONSTRUCTION                  ? 7  1 1 1 ?      ?            
'INITIAL EULER ASSIGNMENT'      ? 8  1 1 1 ?      ?            
'FINAL EULER ASSIGNMENT'        ? 9  1 1 1 ?      ?            
'CTF CORRECTION'                ? 10 1 1 1 ?      ?            
'LAYERLINE INDEXING'            ? 11 1 1 1 ?      ?            
'DIFFRACTION INDEXING'          ? 12 1 1 1 ?      ?            
'MODEL FITTING'                 ? 13 1 1 1 ?      ?            
'SERIES ALIGNMENT'              ? 14 1 1 1 ?      ?            
'MOLECULAR REPLACEMENT'         ? 15 1 1 1 ?      ?            
'LATTICE DISTORTION CORRECTION' ? 16 1 1 1 ?      ?            
'SYMMETRY DETERMINATION'        ? 17 1 1 1 ?      ?            
'CRYSTALLOGRAPHY MERGING'       ? 18 1 1 1 ?      ?            
OTHER                           ? 19 1 1 1 ?      ?            
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Other government' ? 'Shenzhen Science and Technology Innovation Committee' 1 
'Other private'    ? 'Ganghong Young Scholar Development Fund'              2 
# 
_atom_sites.entry_id                    8W8W 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
CA 
N  
O  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . VAL A 1 159 ? 114.883 137.377 97.419  1.00 94.63  ? 38  VAL R N   1 
ATOM   2    C  CA  . VAL A 1 159 ? 115.896 138.106 96.669  1.00 95.91  ? 38  VAL R CA  1 
ATOM   3    C  C   . VAL A 1 159 ? 116.045 139.508 97.240  1.00 96.92  ? 38  VAL R C   1 
ATOM   4    O  O   . VAL A 1 159 ? 117.105 140.123 97.142  1.00 97.07  ? 38  VAL R O   1 
ATOM   5    C  CB  . VAL A 1 159 ? 115.552 138.160 95.171  1.00 95.96  ? 38  VAL R CB  1 
ATOM   6    C  CG1 . VAL A 1 159 ? 116.766 138.587 94.357  1.00 94.63  ? 38  VAL R CG1 1 
ATOM   7    C  CG2 . VAL A 1 159 ? 115.036 136.813 94.700  1.00 95.44  ? 38  VAL R CG2 1 
ATOM   8    N  N   . PHE A 1 160 ? 114.970 140.006 97.844  1.00 94.30  ? 39  PHE R N   1 
ATOM   9    C  CA  . PHE A 1 160 ? 114.955 141.358 98.386  1.00 92.77  ? 39  PHE R CA  1 
ATOM   10   C  C   . PHE A 1 160 ? 114.492 141.297 99.831  1.00 92.60  ? 39  PHE R C   1 
ATOM   11   O  O   . PHE A 1 160 ? 113.466 140.678 100.129 1.00 92.59  ? 39  PHE R O   1 
ATOM   12   C  CB  . PHE A 1 160 ? 114.037 142.267 97.560  1.00 92.76  ? 39  PHE R CB  1 
ATOM   13   C  CG  . PHE A 1 160 ? 113.823 143.624 98.165  1.00 94.03  ? 39  PHE R CG  1 
ATOM   14   C  CD1 . PHE A 1 160 ? 114.817 144.585 98.113  1.00 93.88  ? 39  PHE R CD1 1 
ATOM   15   C  CD2 . PHE A 1 160 ? 112.624 143.939 98.782  1.00 92.94  ? 39  PHE R CD2 1 
ATOM   16   C  CE1 . PHE A 1 160 ? 114.622 145.835 98.668  1.00 93.76  ? 39  PHE R CE1 1 
ATOM   17   C  CE2 . PHE A 1 160 ? 112.422 145.186 99.339  1.00 92.14  ? 39  PHE R CE2 1 
ATOM   18   C  CZ  . PHE A 1 160 ? 113.422 146.136 99.282  1.00 93.47  ? 39  PHE R CZ  1 
ATOM   19   N  N   . ILE A 1 161 ? 115.245 141.938 100.719 1.00 90.46  ? 40  ILE R N   1 
ATOM   20   C  CA  . ILE A 1 161 ? 114.937 141.983 102.142 1.00 91.04  ? 40  ILE R CA  1 
ATOM   21   C  C   . ILE A 1 161 ? 114.484 143.391 102.492 1.00 92.42  ? 40  ILE R C   1 
ATOM   22   O  O   . ILE A 1 161 ? 115.073 144.376 102.033 1.00 90.43  ? 40  ILE R O   1 
ATOM   23   C  CB  . ILE A 1 161 ? 116.145 141.556 102.999 1.00 90.14  ? 40  ILE R CB  1 
ATOM   24   C  CG1 . ILE A 1 161 ? 116.412 140.062 102.826 1.00 90.25  ? 40  ILE R CG1 1 
ATOM   25   C  CG2 . ILE A 1 161 ? 115.925 141.892 104.464 1.00 89.94  ? 40  ILE R CG2 1 
ATOM   26   C  CD1 . ILE A 1 161 ? 115.614 139.192 103.764 1.00 90.32  ? 40  ILE R CD1 1 
ATOM   27   N  N   . LYS A 1 162 ? 113.426 143.481 103.296 1.00 98.34  ? 41  LYS R N   1 
ATOM   28   C  CA  . LYS A 1 162 ? 112.868 144.747 103.746 1.00 97.28  ? 41  LYS R CA  1 
ATOM   29   C  C   . LYS A 1 162 ? 113.941 145.557 104.459 1.00 98.93  ? 41  LYS R C   1 
ATOM   30   O  O   . LYS A 1 162 ? 114.745 144.990 105.208 1.00 99.67  ? 41  LYS R O   1 
ATOM   31   C  CB  . LYS A 1 162 ? 111.688 144.506 104.686 1.00 97.10  ? 41  LYS R CB  1 
ATOM   32   C  CG  . LYS A 1 162 ? 110.531 143.752 104.064 1.00 98.39  ? 41  LYS R CG  1 
ATOM   33   C  CD  . LYS A 1 162 ? 109.447 143.485 105.095 1.00 99.10  ? 41  LYS R CD  1 
ATOM   34   C  CE  . LYS A 1 162 ? 108.281 142.721 104.491 1.00 99.30  ? 41  LYS R CE  1 
ATOM   35   N  NZ  . LYS A 1 162 ? 107.219 142.449 105.500 1.00 98.61  ? 41  LYS R NZ  1 
ATOM   36   N  N   . PRO A 1 163 ? 113.995 146.876 104.253 1.00 98.57  ? 42  PRO R N   1 
ATOM   37   C  CA  . PRO A 1 163 ? 114.977 147.692 104.982 1.00 96.85  ? 42  PRO R CA  1 
ATOM   38   C  C   . PRO A 1 163 ? 114.799 147.649 106.487 1.00 96.74  ? 42  PRO R C   1 
ATOM   39   O  O   . PRO A 1 163 ? 115.770 147.897 107.212 1.00 95.78  ? 42  PRO R O   1 
ATOM   40   C  CB  . PRO A 1 163 ? 114.733 149.107 104.439 1.00 95.46  ? 42  PRO R CB  1 
ATOM   41   C  CG  . PRO A 1 163 ? 114.026 148.908 103.140 1.00 96.59  ? 42  PRO R CG  1 
ATOM   42   C  CD  . PRO A 1 163 ? 113.193 147.681 103.318 1.00 97.18  ? 42  PRO R CD  1 
ATOM   43   N  N   . GLU A 1 164 ? 113.603 147.326 106.975 1.00 94.88  ? 43  GLU R N   1 
ATOM   44   C  CA  . GLU A 1 164 ? 113.307 147.356 108.413 1.00 94.34  ? 43  GLU R CA  1 
ATOM   45   C  C   . GLU A 1 164 ? 114.141 146.332 109.178 1.00 93.22  ? 43  GLU R C   1 
ATOM   46   O  O   . GLU A 1 164 ? 114.525 146.568 110.327 1.00 92.19  ? 43  GLU R O   1 
ATOM   47   C  CB  . GLU A 1 164 ? 111.812 147.123 108.638 1.00 92.34  ? 43  GLU R CB  1 
ATOM   48   C  CG  . GLU A 1 164 ? 110.936 148.279 108.202 1.00 92.81  ? 43  GLU R CG  1 
ATOM   49   C  CD  . GLU A 1 164 ? 110.342 148.067 106.826 1.00 93.89  ? 43  GLU R CD  1 
ATOM   50   O  OE1 . GLU A 1 164 ? 111.118 147.900 105.863 1.00 94.28  ? 43  GLU R OE1 1 
ATOM   51   O  OE2 . GLU A 1 164 ? 109.100 148.066 106.705 1.00 94.26  ? 43  GLU R OE2 1 
ATOM   52   N  N   . VAL A 1 165 ? 114.417 145.188 108.553 1.00 87.18  ? 44  VAL R N   1 
ATOM   53   C  CA  . VAL A 1 165 ? 115.076 144.073 109.226 1.00 87.14  ? 44  VAL R CA  1 
ATOM   54   C  C   . VAL A 1 165 ? 116.475 144.467 109.679 1.00 87.46  ? 44  VAL R C   1 
ATOM   55   O  O   . VAL A 1 165 ? 116.862 144.210 110.825 1.00 86.34  ? 44  VAL R O   1 
ATOM   56   C  CB  . VAL A 1 165 ? 115.126 142.837 108.314 1.00 86.60  ? 44  VAL R CB  1 
ATOM   57   C  CG1 . VAL A 1 165 ? 115.932 141.736 108.968 1.00 86.93  ? 44  VAL R CG1 1 
ATOM   58   C  CG2 . VAL A 1 165 ? 113.719 142.360 107.999 1.00 86.92  ? 44  VAL R CG2 1 
ATOM   59   N  N   . PHE A 1 166 ? 117.243 145.096 108.786 1.00 80.54  ? 45  PHE R N   1 
ATOM   60   C  CA  . PHE A 1 166 ? 118.587 145.530 109.152 1.00 78.83  ? 45  PHE R CA  1 
ATOM   61   C  C   . PHE A 1 166 ? 118.544 146.570 110.264 1.00 81.09  ? 45  PHE R C   1 
ATOM   62   O  O   . PHE A 1 166 ? 119.318 146.495 111.226 1.00 81.14  ? 45  PHE R O   1 
ATOM   63   C  CB  . PHE A 1 166 ? 119.313 146.080 107.926 1.00 77.47  ? 45  PHE R CB  1 
ATOM   64   C  CG  . PHE A 1 166 ? 119.538 145.061 106.846 1.00 77.81  ? 45  PHE R CG  1 
ATOM   65   C  CD1 . PHE A 1 166 ? 120.582 144.160 106.932 1.00 75.31  ? 45  PHE R CD1 1 
ATOM   66   C  CD2 . PHE A 1 166 ? 118.705 145.007 105.742 1.00 79.65  ? 45  PHE R CD2 1 
ATOM   67   C  CE1 . PHE A 1 166 ? 120.791 143.227 105.943 1.00 76.80  ? 45  PHE R CE1 1 
ATOM   68   C  CE2 . PHE A 1 166 ? 118.911 144.073 104.749 1.00 78.62  ? 45  PHE R CE2 1 
ATOM   69   C  CZ  . PHE A 1 166 ? 119.955 143.181 104.851 1.00 78.09  ? 45  PHE R CZ  1 
ATOM   70   N  N   . LEU A 1 167 ? 117.630 147.538 110.160 1.00 84.91  ? 46  LEU R N   1 
ATOM   71   C  CA  . LEU A 1 167 ? 117.463 148.519 111.227 1.00 84.31  ? 46  LEU R CA  1 
ATOM   72   C  C   . LEU A 1 167 ? 116.998 147.860 112.517 1.00 84.81  ? 46  LEU R C   1 
ATOM   73   O  O   . LEU A 1 167 ? 117.427 148.247 113.609 1.00 85.01  ? 46  LEU R O   1 
ATOM   74   C  CB  . LEU A 1 167 ? 116.473 149.602 110.804 1.00 82.10  ? 46  LEU R CB  1 
ATOM   75   C  CG  . LEU A 1 167 ? 116.773 150.390 109.534 1.00 82.73  ? 46  LEU R CG  1 
ATOM   76   C  CD1 . LEU A 1 167 ? 115.502 150.616 108.742 1.00 84.29  ? 46  LEU R CD1 1 
ATOM   77   C  CD2 . LEU A 1 167 ? 117.402 151.710 109.908 1.00 83.03  ? 46  LEU R CD2 1 
ATOM   78   N  N   . SER A 1 168 ? 116.105 146.874 112.413 1.00 81.51  ? 47  SER R N   1 
ATOM   79   C  CA  . SER A 1 168 ? 115.609 146.200 113.608 1.00 80.58  ? 47  SER R CA  1 
ATOM   80   C  C   . SER A 1 168 ? 116.728 145.469 114.338 1.00 81.31  ? 47  SER R C   1 
ATOM   81   O  O   . SER A 1 168 ? 116.789 145.496 115.571 1.00 82.56  ? 47  SER R O   1 
ATOM   82   C  CB  . SER A 1 168 ? 114.489 145.230 113.237 1.00 82.48  ? 47  SER R CB  1 
ATOM   83   O  OG  . SER A 1 168 ? 114.302 144.261 114.252 1.00 83.33  ? 47  SER R OG  1 
ATOM   84   N  N   . LEU A 1 169 ? 117.619 144.808 113.597 1.00 74.95  ? 48  LEU R N   1 
ATOM   85   C  CA  . LEU A 1 169 ? 118.716 144.089 114.237 1.00 75.18  ? 48  LEU R CA  1 
ATOM   86   C  C   . LEU A 1 169 ? 119.789 145.046 114.745 1.00 75.99  ? 48  LEU R C   1 
ATOM   87   O  O   . LEU A 1 169 ? 120.439 144.775 115.767 1.00 75.39  ? 48  LEU R O   1 
ATOM   88   C  CB  . LEU A 1 169 ? 119.317 143.080 113.264 1.00 72.88  ? 48  LEU R CB  1 
ATOM   89   C  CG  . LEU A 1 169 ? 118.418 141.913 112.864 1.00 73.95  ? 48  LEU R CG  1 
ATOM   90   C  CD1 . LEU A 1 169 ? 119.000 141.168 111.678 1.00 72.10  ? 48  LEU R CD1 1 
ATOM   91   C  CD2 . LEU A 1 169 ? 118.221 140.979 114.039 1.00 73.70  ? 48  LEU R CD2 1 
ATOM   92   N  N   . GLY A 1 170 ? 119.990 146.167 114.045 1.00 75.75  ? 49  GLY R N   1 
ATOM   93   C  CA  . GLY A 1 170 ? 121.059 147.079 114.415 1.00 74.84  ? 49  GLY R CA  1 
ATOM   94   C  C   . GLY A 1 170 ? 120.895 147.653 115.808 1.00 76.22  ? 49  GLY R C   1 
ATOM   95   O  O   . GLY A 1 170 ? 121.840 147.674 116.597 1.00 78.07  ? 49  GLY R O   1 
ATOM   96   N  N   . ILE A 1 171 ? 119.688 148.113 116.135 1.00 75.96  ? 50  ILE R N   1 
ATOM   97   C  CA  . ILE A 1 171 ? 119.471 148.750 117.431 1.00 76.13  ? 50  ILE R CA  1 
ATOM   98   C  C   . ILE A 1 171 ? 119.578 147.734 118.564 1.00 76.22  ? 50  ILE R C   1 
ATOM   99   O  O   . ILE A 1 171 ? 120.141 148.030 119.626 1.00 78.03  ? 50  ILE R O   1 
ATOM   100  C  CB  . ILE A 1 171 ? 118.122 149.495 117.441 1.00 77.41  ? 50  ILE R CB  1 
ATOM   101  C  CG1 . ILE A 1 171 ? 116.953 148.522 117.259 1.00 78.03  ? 50  ILE R CG1 1 
ATOM   102  C  CG2 . ILE A 1 171 ? 118.108 150.581 116.372 1.00 74.95  ? 50  ILE R CG2 1 
ATOM   103  C  CD1 . ILE A 1 171 ? 115.674 149.175 116.778 1.00 76.46  ? 50  ILE R CD1 1 
ATOM   104  N  N   . VAL A 1 172 ? 119.062 146.521 118.358 1.00 70.73  ? 51  VAL R N   1 
ATOM   105  C  CA  . VAL A 1 172 ? 119.118 145.505 119.405 1.00 73.55  ? 51  VAL R CA  1 
ATOM   106  C  C   . VAL A 1 172 ? 120.562 145.106 119.684 1.00 74.13  ? 51  VAL R C   1 
ATOM   107  O  O   . VAL A 1 172 ? 120.987 145.019 120.844 1.00 73.04  ? 51  VAL R O   1 
ATOM   108  C  CB  . VAL A 1 172 ? 118.262 144.286 119.023 1.00 71.15  ? 51  VAL R CB  1 
ATOM   109  C  CG1 . VAL A 1 172 ? 118.230 143.294 120.168 1.00 69.84  ? 51  VAL R CG1 1 
ATOM   110  C  CG2 . VAL A 1 172 ? 116.857 144.722 118.659 1.00 71.37  ? 51  VAL R CG2 1 
ATOM   111  N  N   . SER A 1 173 ? 121.341 144.858 118.626 1.00 70.62  ? 52  SER R N   1 
ATOM   112  C  CA  . SER A 1 173 ? 122.740 144.503 118.834 1.00 69.05  ? 52  SER R CA  1 
ATOM   113  C  C   . SER A 1 173 ? 123.521 145.663 119.440 1.00 68.92  ? 52  SER R C   1 
ATOM   114  O  O   . SER A 1 173 ? 124.398 145.451 120.287 1.00 73.24  ? 52  SER R O   1 
ATOM   115  C  CB  . SER A 1 173 ? 123.376 144.076 117.524 1.00 66.59  ? 52  SER R CB  1 
ATOM   116  O  OG  . SER A 1 173 ? 123.381 145.170 116.639 1.00 69.68  ? 52  SER R OG  1 
ATOM   117  N  N   . LEU A 1 174 ? 123.233 146.894 119.005 1.00 65.99  ? 53  LEU R N   1 
ATOM   118  C  CA  . LEU A 1 174 ? 123.833 148.073 119.618 1.00 68.87  ? 53  LEU R CA  1 
ATOM   119  C  C   . LEU A 1 174 ? 123.616 148.077 121.122 1.00 71.19  ? 53  LEU R C   1 
ATOM   120  O  O   . LEU A 1 174 ? 124.565 148.219 121.903 1.00 70.10  ? 53  LEU R O   1 
ATOM   121  C  CB  . LEU A 1 174 ? 123.228 149.334 119.000 1.00 69.77  ? 53  LEU R CB  1 
ATOM   122  C  CG  . LEU A 1 174 ? 124.033 150.629 118.968 1.00 70.38  ? 53  LEU R CG  1 
ATOM   123  C  CD1 . LEU A 1 174 ? 125.289 150.450 118.168 1.00 68.36  ? 53  LEU R CD1 1 
ATOM   124  C  CD2 . LEU A 1 174 ? 123.188 151.752 118.392 1.00 69.89  ? 53  LEU R CD2 1 
ATOM   125  N  N   . LEU A 1 175 ? 122.360 147.912 121.541 1.00 69.29  ? 54  LEU R N   1 
ATOM   126  C  CA  . LEU A 1 175 ? 122.037 147.943 122.962 1.00 69.21  ? 54  LEU R CA  1 
ATOM   127  C  C   . LEU A 1 175 ? 122.761 146.833 123.710 1.00 71.14  ? 54  LEU R C   1 
ATOM   128  O  O   . LEU A 1 175 ? 123.352 147.067 124.771 1.00 71.56  ? 54  LEU R O   1 
ATOM   129  C  CB  . LEU A 1 175 ? 120.524 147.826 123.153 1.00 69.06  ? 54  LEU R CB  1 
ATOM   130  C  CG  . LEU A 1 175 ? 119.722 149.117 123.352 1.00 71.75  ? 54  LEU R CG  1 
ATOM   131  C  CD1 . LEU A 1 175 ? 119.924 149.670 124.755 1.00 70.74  ? 54  LEU R CD1 1 
ATOM   132  C  CD2 . LEU A 1 175 ? 120.090 150.158 122.306 1.00 69.75  ? 54  LEU R CD2 1 
ATOM   133  N  N   . GLU A 1 176 ? 122.748 145.617 123.156 1.00 66.24  ? 55  GLU R N   1 
ATOM   134  C  CA  . GLU A 1 176 ? 123.338 144.480 123.858 1.00 61.39  ? 55  GLU R CA  1 
ATOM   135  C  C   . GLU A 1 176 ? 124.840 144.654 124.037 1.00 60.32  ? 55  GLU R C   1 
ATOM   136  O  O   . GLU A 1 176 ? 125.376 144.450 125.133 1.00 61.09  ? 55  GLU R O   1 
ATOM   137  C  CB  . GLU A 1 176 ? 123.036 143.190 123.103 1.00 62.01  ? 55  GLU R CB  1 
ATOM   138  C  CG  . GLU A 1 176 ? 121.607 142.726 123.228 1.00 65.94  ? 55  GLU R CG  1 
ATOM   139  C  CD  . GLU A 1 176 ? 121.396 141.362 122.623 1.00 67.77  ? 55  GLU R CD  1 
ATOM   140  O  OE1 . GLU A 1 176 ? 122.401 140.660 122.400 1.00 66.96  ? 55  GLU R OE1 1 
ATOM   141  O  OE2 . GLU A 1 176 ? 120.232 140.991 122.368 1.00 68.18  ? 55  GLU R OE2 1 
ATOM   142  N  N   . ASN A 1 177 ? 125.542 145.039 122.971 1.00 59.64  ? 56  ASN R N   1 
ATOM   143  C  CA  . ASN A 1 177 ? 126.993 145.152 123.062 1.00 60.34  ? 56  ASN R CA  1 
ATOM   144  C  C   . ASN A 1 177 ? 127.419 146.368 123.881 1.00 65.34  ? 56  ASN R C   1 
ATOM   145  O  O   . ASN A 1 177 ? 128.436 146.311 124.587 1.00 68.14  ? 56  ASN R O   1 
ATOM   146  C  CB  . ASN A 1 177 ? 127.592 145.184 121.660 1.00 59.63  ? 56  ASN R CB  1 
ATOM   147  C  CG  . ASN A 1 177 ? 127.275 143.930 120.870 1.00 60.57  ? 56  ASN R CG  1 
ATOM   148  O  OD1 . ASN A 1 177 ? 126.668 143.987 119.807 1.00 62.55  ? 56  ASN R OD1 1 
ATOM   149  N  ND2 . ASN A 1 177 ? 127.686 142.786 121.393 1.00 59.92  ? 56  ASN R ND2 1 
ATOM   150  N  N   . ILE A 1 178 ? 126.651 147.461 123.831 1.00 69.29  ? 57  ILE R N   1 
ATOM   151  C  CA  . ILE A 1 178 ? 126.922 148.591 124.714 1.00 68.52  ? 57  ILE R CA  1 
ATOM   152  C  C   . ILE A 1 178 ? 126.757 148.173 126.169 1.00 66.52  ? 57  ILE R C   1 
ATOM   153  O  O   . ILE A 1 178 ? 127.567 148.537 127.029 1.00 64.94  ? 57  ILE R O   1 
ATOM   154  C  CB  . ILE A 1 178 ? 126.011 149.781 124.355 1.00 68.51  ? 57  ILE R CB  1 
ATOM   155  C  CG1 . ILE A 1 178 ? 126.604 150.576 123.192 1.00 68.41  ? 57  ILE R CG1 1 
ATOM   156  C  CG2 . ILE A 1 178 ? 125.802 150.690 125.553 1.00 68.52  ? 57  ILE R CG2 1 
ATOM   157  C  CD1 . ILE A 1 178 ? 127.880 151.300 123.539 1.00 66.78  ? 57  ILE R CD1 1 
ATOM   158  N  N   . LEU A 1 179 ? 125.710 147.397 126.466 1.00 67.24  ? 58  LEU R N   1 
ATOM   159  C  CA  . LEU A 1 179 ? 125.499 146.926 127.831 1.00 67.55  ? 58  LEU R CA  1 
ATOM   160  C  C   . LEU A 1 179 ? 126.637 146.016 128.278 1.00 66.70  ? 58  LEU R C   1 
ATOM   161  O  O   . LEU A 1 179 ? 127.069 146.076 129.433 1.00 69.46  ? 58  LEU R O   1 
ATOM   162  C  CB  . LEU A 1 179 ? 124.152 146.207 127.925 1.00 70.29  ? 58  LEU R CB  1 
ATOM   163  C  CG  . LEU A 1 179 ? 123.366 146.111 129.241 1.00 68.25  ? 58  LEU R CG  1 
ATOM   164  C  CD1 . LEU A 1 179 ? 122.055 145.377 129.002 1.00 67.99  ? 58  LEU R CD1 1 
ATOM   165  C  CD2 . LEU A 1 179 ? 124.143 145.430 130.355 1.00 67.01  ? 58  LEU R CD2 1 
ATOM   166  N  N   . VAL A 1 180 ? 127.133 145.163 127.380 1.00 66.13  ? 59  VAL R N   1 
ATOM   167  C  CA  . VAL A 1 180 ? 128.253 144.288 127.726 1.00 68.13  ? 59  VAL R CA  1 
ATOM   168  C  C   . VAL A 1 180 ? 129.490 145.114 128.064 1.00 65.94  ? 59  VAL R C   1 
ATOM   169  O  O   . VAL A 1 180 ? 130.164 144.876 129.078 1.00 68.00  ? 59  VAL R O   1 
ATOM   170  C  CB  . VAL A 1 180 ? 128.534 143.295 126.582 1.00 67.14  ? 59  VAL R CB  1 
ATOM   171  C  CG1 . VAL A 1 180 ? 129.879 142.617 126.778 1.00 66.49  ? 59  VAL R CG1 1 
ATOM   172  C  CG2 . VAL A 1 180 ? 127.429 142.264 126.493 1.00 64.50  ? 59  VAL R CG2 1 
ATOM   173  N  N   . ILE A 1 181 ? 129.802 146.102 127.222 1.00 66.61  ? 60  ILE R N   1 
ATOM   174  C  CA  . ILE A 1 181 ? 130.968 146.946 127.475 1.00 66.73  ? 60  ILE R CA  1 
ATOM   175  C  C   . ILE A 1 181 ? 130.811 147.690 128.794 1.00 70.78  ? 60  ILE R C   1 
ATOM   176  O  O   . ILE A 1 181 ? 131.763 147.810 129.575 1.00 69.27  ? 60  ILE R O   1 
ATOM   177  C  CB  . ILE A 1 181 ? 131.196 147.914 126.299 1.00 66.23  ? 60  ILE R CB  1 
ATOM   178  C  CG1 . ILE A 1 181 ? 131.719 147.157 125.081 1.00 68.74  ? 60  ILE R CG1 1 
ATOM   179  C  CG2 . ILE A 1 181 ? 132.178 148.997 126.685 1.00 67.05  ? 60  ILE R CG2 1 
ATOM   180  C  CD1 . ILE A 1 181 ? 132.022 148.039 123.900 1.00 66.97  ? 60  ILE R CD1 1 
ATOM   181  N  N   . LEU A 1 182 ? 129.607 148.197 129.068 1.00 77.14  ? 61  LEU R N   1 
ATOM   182  C  CA  . LEU A 1 182 ? 129.370 148.914 130.317 1.00 73.58  ? 61  LEU R CA  1 
ATOM   183  C  C   . LEU A 1 182 ? 129.558 148.000 131.521 1.00 71.68  ? 61  LEU R C   1 
ATOM   184  O  O   . LEU A 1 182 ? 130.234 148.364 132.488 1.00 75.97  ? 61  LEU R O   1 
ATOM   185  C  CB  . LEU A 1 182 ? 127.965 149.517 130.316 1.00 74.45  ? 61  LEU R CB  1 
ATOM   186  C  CG  . LEU A 1 182 ? 127.764 150.801 129.509 1.00 74.39  ? 61  LEU R CG  1 
ATOM   187  C  CD1 . LEU A 1 182 ? 126.383 151.374 129.763 1.00 72.91  ? 61  LEU R CD1 1 
ATOM   188  C  CD2 . LEU A 1 182 ? 128.839 151.819 129.840 1.00 71.69  ? 61  LEU R CD2 1 
ATOM   189  N  N   . ALA A 1 183 ? 128.974 146.799 131.472 1.00 76.89  ? 62  ALA R N   1 
ATOM   190  C  CA  . ALA A 1 183 ? 129.077 145.875 132.596 1.00 78.44  ? 62  ALA R CA  1 
ATOM   191  C  C   . ALA A 1 183 ? 130.517 145.468 132.856 1.00 77.94  ? 62  ALA R C   1 
ATOM   192  O  O   . ALA A 1 183 ? 130.900 145.253 134.010 1.00 78.63  ? 62  ALA R O   1 
ATOM   193  C  CB  . ALA A 1 183 ? 128.216 144.637 132.349 1.00 77.03  ? 62  ALA R CB  1 
ATOM   194  N  N   . VAL A 1 184 ? 131.329 145.345 131.806 1.00 78.42  ? 63  VAL R N   1 
ATOM   195  C  CA  . VAL A 1 184 ? 132.750 145.104 132.035 1.00 78.80  ? 63  VAL R CA  1 
ATOM   196  C  C   . VAL A 1 184 ? 133.406 146.334 132.652 1.00 78.33  ? 63  VAL R C   1 
ATOM   197  O  O   . VAL A 1 184 ? 134.234 146.221 133.562 1.00 78.16  ? 63  VAL R O   1 
ATOM   198  C  CB  . VAL A 1 184 ? 133.450 144.677 130.733 1.00 78.48  ? 63  VAL R CB  1 
ATOM   199  C  CG1 . VAL A 1 184 ? 134.936 144.500 130.972 1.00 77.62  ? 63  VAL R CG1 1 
ATOM   200  C  CG2 . VAL A 1 184 ? 132.847 143.390 130.208 1.00 76.82  ? 63  VAL R CG2 1 
ATOM   201  N  N   . VAL A 1 185 ? 133.045 147.528 132.174 1.00 83.21  ? 64  VAL R N   1 
ATOM   202  C  CA  . VAL A 1 185 ? 133.660 148.755 132.679 1.00 84.38  ? 64  VAL R CA  1 
ATOM   203  C  C   . VAL A 1 185 ? 133.203 149.050 134.104 1.00 83.34  ? 64  VAL R C   1 
ATOM   204  O  O   . VAL A 1 185 ? 133.992 149.505 134.941 1.00 81.60  ? 64  VAL R O   1 
ATOM   205  C  CB  . VAL A 1 185 ? 133.367 149.927 131.726 1.00 84.07  ? 64  VAL R CB  1 
ATOM   206  C  CG1 . VAL A 1 185 ? 133.609 151.258 132.417 1.00 82.49  ? 64  VAL R CG1 1 
ATOM   207  C  CG2 . VAL A 1 185 ? 134.229 149.815 130.479 1.00 82.54  ? 64  VAL R CG2 1 
ATOM   208  N  N   . ARG A 1 186 ? 131.938 148.766 134.417 1.00 87.80  ? 65  ARG R N   1 
ATOM   209  C  CA  . ARG A 1 186 ? 131.363 149.051 135.727 1.00 87.19  ? 65  ARG R CA  1 
ATOM   210  C  C   . ARG A 1 186 ? 131.793 148.046 136.786 1.00 89.11  ? 65  ARG R C   1 
ATOM   211  O  O   . ARG A 1 186 ? 131.128 147.906 137.818 1.00 89.39  ? 65  ARG R O   1 
ATOM   212  C  CB  . ARG A 1 186 ? 129.838 149.098 135.637 1.00 85.04  ? 65  ARG R CB  1 
ATOM   213  C  CG  . ARG A 1 186 ? 129.296 150.450 135.215 1.00 84.87  ? 65  ARG R CG  1 
ATOM   214  C  CD  . ARG A 1 186 ? 128.836 151.261 136.415 1.00 87.02  ? 65  ARG R CD  1 
ATOM   215  N  NE  . ARG A 1 186 ? 127.475 150.922 136.809 1.00 89.83  ? 65  ARG R NE  1 
ATOM   216  C  CZ  . ARG A 1 186 ? 126.385 151.367 136.199 1.00 89.69  ? 65  ARG R CZ  1 
ATOM   217  N  NH1 . ARG A 1 186 ? 126.458 152.183 135.160 1.00 85.71  ? 65  ARG R NH1 1 
ATOM   218  N  NH2 . ARG A 1 186 ? 125.191 150.985 136.643 1.00 88.93  ? 65  ARG R NH2 1 
ATOM   219  N  N   . ASN A 1 187 ? 132.885 147.341 136.521 1.00 90.98  ? 66  ASN R N   1 
ATOM   220  C  CA  . ASN A 1 187 ? 133.512 146.418 137.455 1.00 88.88  ? 66  ASN R CA  1 
ATOM   221  C  C   . ASN A 1 187 ? 135.010 146.670 137.343 1.00 90.82  ? 66  ASN R C   1 
ATOM   222  O  O   . ASN A 1 187 ? 135.434 147.724 136.855 1.00 91.78  ? 66  ASN R O   1 
ATOM   223  C  CB  . ASN A 1 187 ? 133.105 144.970 137.151 1.00 91.87  ? 66  ASN R CB  1 
ATOM   224  C  CG  . ASN A 1 187 ? 132.586 144.246 138.371 1.00 92.46  ? 66  ASN R CG  1 
ATOM   225  O  OD1 . ASN A 1 187 ? 132.700 144.739 139.493 1.00 90.35  ? 66  ASN R OD1 1 
ATOM   226  N  ND2 . ASN A 1 187 ? 132.010 143.068 138.161 1.00 91.79  ? 66  ASN R ND2 1 
ATOM   227  N  N   . GLY A 1 188 ? 135.821 145.732 137.829 1.00 93.73  ? 67  GLY R N   1 
ATOM   228  C  CA  . GLY A 1 188 ? 137.264 145.844 137.708 1.00 94.11  ? 67  GLY R CA  1 
ATOM   229  C  C   . GLY A 1 188 ? 137.713 146.344 136.348 1.00 96.04  ? 67  GLY R C   1 
ATOM   230  O  O   . GLY A 1 188 ? 137.448 145.709 135.324 1.00 95.41  ? 67  GLY R O   1 
ATOM   231  N  N   . ASN A 1 189 ? 138.383 147.499 136.330 1.00 94.85  ? 68  ASN R N   1 
ATOM   232  C  CA  . ASN A 1 189 ? 138.697 148.158 135.066 1.00 93.97  ? 68  ASN R CA  1 
ATOM   233  C  C   . ASN A 1 189 ? 139.692 147.351 134.243 1.00 94.99  ? 68  ASN R C   1 
ATOM   234  O  O   . ASN A 1 189 ? 139.646 147.370 133.007 1.00 95.56  ? 68  ASN R O   1 
ATOM   235  C  CB  . ASN A 1 189 ? 139.237 149.564 135.330 1.00 94.77  ? 68  ASN R CB  1 
ATOM   236  N  N   . LEU A 1 190 ? 140.601 146.642 134.907 1.00 90.74  ? 69  LEU R N   1 
ATOM   237  C  CA  . LEU A 1 190 ? 141.615 145.852 134.219 1.00 92.08  ? 69  LEU R CA  1 
ATOM   238  C  C   . LEU A 1 190 ? 141.470 144.387 134.601 1.00 90.19  ? 69  LEU R C   1 
ATOM   239  O  O   . LEU A 1 190 ? 142.454 143.735 134.965 1.00 89.05  ? 69  LEU R O   1 
ATOM   240  C  CB  . LEU A 1 190 ? 143.020 146.365 134.543 1.00 91.30  ? 69  LEU R CB  1 
ATOM   241  C  CG  . LEU A 1 190 ? 143.745 147.063 133.390 1.00 90.90  ? 69  LEU R CG  1 
ATOM   242  C  CD1 . LEU A 1 190 ? 143.131 148.428 133.114 1.00 88.37  ? 69  LEU R CD1 1 
ATOM   243  C  CD2 . LEU A 1 190 ? 145.232 147.186 133.679 1.00 90.62  ? 69  LEU R CD2 1 
ATOM   244  N  N   . HIS A 1 191 ? 140.237 143.879 134.515 1.00 83.73  ? 70  HIS R N   1 
ATOM   245  C  CA  . HIS A 1 191 ? 139.859 142.575 135.047 1.00 84.55  ? 70  HIS R CA  1 
ATOM   246  C  C   . HIS A 1 191 ? 140.904 141.490 134.806 1.00 86.78  ? 70  HIS R C   1 
ATOM   247  O  O   . HIS A 1 191 ? 141.517 140.977 135.749 1.00 87.61  ? 70  HIS R O   1 
ATOM   248  C  CB  . HIS A 1 191 ? 138.539 142.147 134.401 1.00 83.86  ? 70  HIS R CB  1 
ATOM   249  C  CG  . HIS A 1 191 ? 137.351 142.243 135.301 1.00 84.73  ? 70  HIS R CG  1 
ATOM   250  N  ND1 . HIS A 1 191 ? 137.238 141.511 136.462 1.00 86.53  ? 70  HIS R ND1 1 
ATOM   251  C  CD2 . HIS A 1 191 ? 136.198 142.940 135.180 1.00 83.75  ? 70  HIS R CD2 1 
ATOM   252  C  CE1 . HIS A 1 191 ? 136.077 141.777 137.034 1.00 87.06  ? 70  HIS R CE1 1 
ATOM   253  N  NE2 . HIS A 1 191 ? 135.427 142.640 136.275 1.00 87.34  ? 70  HIS R NE2 1 
ATOM   254  N  N   . SER A 1 192 ? 141.133 141.153 133.542 1.00 75.31  ? 71  SER R N   1 
ATOM   255  C  CA  . SER A 1 192 ? 141.937 139.998 133.171 1.00 72.90  ? 71  SER R CA  1 
ATOM   256  C  C   . SER A 1 192 ? 142.078 139.965 131.658 1.00 72.23  ? 71  SER R C   1 
ATOM   257  O  O   . SER A 1 192 ? 141.359 140.688 130.960 1.00 73.12  ? 71  SER R O   1 
ATOM   258  C  CB  . SER A 1 192 ? 141.288 138.705 133.672 1.00 73.12  ? 71  SER R CB  1 
ATOM   259  O  OG  . SER A 1 192 ? 141.550 138.497 135.048 1.00 73.02  ? 71  SER R OG  1 
ATOM   260  N  N   . PRO A 1 193 ? 142.983 139.155 131.105 1.00 61.33  ? 72  PRO R N   1 
ATOM   261  C  CA  . PRO A 1 193 ? 142.981 138.961 129.648 1.00 60.61  ? 72  PRO R CA  1 
ATOM   262  C  C   . PRO A 1 193 ? 141.705 138.324 129.133 1.00 57.32  ? 72  PRO R C   1 
ATOM   263  O  O   . PRO A 1 193 ? 141.423 138.422 127.936 1.00 57.46  ? 72  PRO R O   1 
ATOM   264  C  CB  . PRO A 1 193 ? 144.197 138.058 129.412 1.00 58.52  ? 72  PRO R CB  1 
ATOM   265  C  CG  . PRO A 1 193 ? 145.082 138.324 130.569 1.00 59.76  ? 72  PRO R CG  1 
ATOM   266  C  CD  . PRO A 1 193 ? 144.175 138.563 131.733 1.00 59.93  ? 72  PRO R CD  1 
ATOM   267  N  N   . MET A 1 194 ? 140.926 137.675 129.997 1.00 57.94  ? 73  MET R N   1 
ATOM   268  C  CA  . MET A 1 194 ? 139.711 137.005 129.551 1.00 55.75  ? 73  MET R CA  1 
ATOM   269  C  C   . MET A 1 194 ? 138.660 137.999 129.076 1.00 56.60  ? 73  MET R C   1 
ATOM   270  O  O   . MET A 1 194 ? 137.938 137.727 128.111 1.00 59.16  ? 73  MET R O   1 
ATOM   271  C  CB  . MET A 1 194 ? 139.159 136.132 130.677 1.00 59.29  ? 73  MET R CB  1 
ATOM   272  C  CG  . MET A 1 194 ? 137.679 135.813 130.563 1.00 61.89  ? 73  MET R CG  1 
ATOM   273  S  SD  . MET A 1 194 ? 137.044 134.856 131.954 1.00 72.16  ? 73  MET R SD  1 
ATOM   274  C  CE  . MET A 1 194 ? 138.551 134.123 132.590 1.00 55.38  ? 73  MET R CE  1 
ATOM   275  N  N   . TYR A 1 195 ? 138.554 139.153 129.736 1.00 59.04  ? 74  TYR R N   1 
ATOM   276  C  CA  . TYR A 1 195 ? 137.482 140.100 129.446 1.00 59.25  ? 74  TYR R CA  1 
ATOM   277  C  C   . TYR A 1 195 ? 137.859 141.150 128.413 1.00 57.09  ? 74  TYR R C   1 
ATOM   278  O  O   . TYR A 1 195 ? 136.966 141.777 127.831 1.00 57.70  ? 74  TYR R O   1 
ATOM   279  C  CB  . TYR A 1 195 ? 137.033 140.791 130.732 1.00 60.10  ? 74  TYR R CB  1 
ATOM   280  C  CG  . TYR A 1 195 ? 136.323 139.864 131.686 1.00 60.43  ? 74  TYR R CG  1 
ATOM   281  C  CD1 . TYR A 1 195 ? 135.026 139.444 131.437 1.00 61.05  ? 74  TYR R CD1 1 
ATOM   282  C  CD2 . TYR A 1 195 ? 136.953 139.400 132.829 1.00 60.03  ? 74  TYR R CD2 1 
ATOM   283  C  CE1 . TYR A 1 195 ? 134.375 138.595 132.302 1.00 62.27  ? 74  TYR R CE1 1 
ATOM   284  C  CE2 . TYR A 1 195 ? 136.310 138.550 133.701 1.00 62.43  ? 74  TYR R CE2 1 
ATOM   285  C  CZ  . TYR A 1 195 ? 135.020 138.150 133.433 1.00 64.11  ? 74  TYR R CZ  1 
ATOM   286  O  OH  . TYR A 1 195 ? 134.372 137.303 134.300 1.00 64.23  ? 74  TYR R OH  1 
ATOM   287  N  N   . PHE A 1 196 ? 139.151 141.343 128.154 1.00 53.72  ? 75  PHE R N   1 
ATOM   288  C  CA  . PHE A 1 196 ? 139.556 142.234 127.076 1.00 53.93  ? 75  PHE R CA  1 
ATOM   289  C  C   . PHE A 1 196 ? 139.096 141.699 125.727 1.00 54.65  ? 75  PHE R C   1 
ATOM   290  O  O   . PHE A 1 196 ? 138.652 142.463 124.860 1.00 54.98  ? 75  PHE R O   1 
ATOM   291  C  CB  . PHE A 1 196 ? 141.069 142.424 127.105 1.00 53.85  ? 75  PHE R CB  1 
ATOM   292  C  CG  . PHE A 1 196 ? 141.568 143.106 128.349 1.00 60.42  ? 75  PHE R CG  1 
ATOM   293  C  CD1 . PHE A 1 196 ? 140.715 143.876 129.122 1.00 57.52  ? 75  PHE R CD1 1 
ATOM   294  C  CD2 . PHE A 1 196 ? 142.887 142.978 128.745 1.00 61.03  ? 75  PHE R CD2 1 
ATOM   295  C  CE1 . PHE A 1 196 ? 141.162 144.500 130.262 1.00 56.16  ? 75  PHE R CE1 1 
ATOM   296  C  CE2 . PHE A 1 196 ? 143.343 143.606 129.887 1.00 58.36  ? 75  PHE R CE2 1 
ATOM   297  C  CZ  . PHE A 1 196 ? 142.476 144.367 130.645 1.00 59.30  ? 75  PHE R CZ  1 
ATOM   298  N  N   . PHE A 1 197 ? 139.179 140.381 125.539 1.00 46.95  ? 76  PHE R N   1 
ATOM   299  C  CA  . PHE A 1 197 ? 138.710 139.769 124.302 1.00 37.28  ? 76  PHE R CA  1 
ATOM   300  C  C   . PHE A 1 197 ? 137.199 139.876 124.171 1.00 39.71  ? 76  PHE R C   1 
ATOM   301  O  O   . PHE A 1 197 ? 136.682 140.078 123.068 1.00 46.57  ? 76  PHE R O   1 
ATOM   302  C  CB  . PHE A 1 197 ? 139.159 138.314 124.242 1.00 35.39  ? 76  PHE R CB  1 
ATOM   303  C  CG  . PHE A 1 197 ? 140.640 138.150 124.103 1.00 39.80  ? 76  PHE R CG  1 
ATOM   304  C  CD1 . PHE A 1 197 ? 141.304 138.646 123.002 1.00 40.26  ? 76  PHE R CD1 1 
ATOM   305  C  CD2 . PHE A 1 197 ? 141.367 137.501 125.072 1.00 35.95  ? 76  PHE R CD2 1 
ATOM   306  C  CE1 . PHE A 1 197 ? 142.664 138.496 122.874 1.00 35.87  ? 76  PHE R CE1 1 
ATOM   307  C  CE2 . PHE A 1 197 ? 142.724 137.352 124.950 1.00 37.62  ? 76  PHE R CE2 1 
ATOM   308  C  CZ  . PHE A 1 197 ? 143.374 137.847 123.851 1.00 37.20  ? 76  PHE R CZ  1 
ATOM   309  N  N   . LEU A 1 198 ? 136.472 139.749 125.282 1.00 39.11  ? 77  LEU R N   1 
ATOM   310  C  CA  . LEU A 1 198 ? 135.027 139.950 125.240 1.00 40.22  ? 77  LEU R CA  1 
ATOM   311  C  C   . LEU A 1 198 ? 134.681 141.377 124.837 1.00 45.98  ? 77  LEU R C   1 
ATOM   312  O  O   . LEU A 1 198 ? 133.783 141.599 124.017 1.00 49.11  ? 77  LEU R O   1 
ATOM   313  C  CB  . LEU A 1 198 ? 134.410 139.618 126.596 1.00 41.84  ? 77  LEU R CB  1 
ATOM   314  C  CG  . LEU A 1 198 ? 134.278 138.138 126.942 1.00 45.72  ? 77  LEU R CG  1 
ATOM   315  C  CD1 . LEU A 1 198 ? 133.450 137.970 128.193 1.00 47.68  ? 77  LEU R CD1 1 
ATOM   316  C  CD2 . LEU A 1 198 ? 133.655 137.382 125.795 1.00 43.91  ? 77  LEU R CD2 1 
ATOM   317  N  N   . CYS A 1 199 ? 135.392 142.358 125.398 1.00 49.64  ? 78  CYS R N   1 
ATOM   318  C  CA  . CYS A 1 199 ? 135.147 143.748 125.029 1.00 46.41  ? 78  CYS R CA  1 
ATOM   319  C  C   . CYS A 1 199 ? 135.441 143.993 123.553 1.00 46.80  ? 78  CYS R C   1 
ATOM   320  O  O   . CYS A 1 199 ? 134.672 144.676 122.866 1.00 54.01  ? 78  CYS R O   1 
ATOM   321  C  CB  . CYS A 1 199 ? 135.982 144.678 125.904 1.00 46.90  ? 78  CYS R CB  1 
ATOM   322  S  SG  . CYS A 1 199 ? 135.169 145.170 127.432 1.00 60.87  ? 78  CYS R SG  1 
ATOM   323  N  N   . SER A 1 200 ? 136.549 143.445 123.046 1.00 36.66  ? 79  SER R N   1 
ATOM   324  C  CA  . SER A 1 200 ? 136.879 143.629 121.635 1.00 36.82  ? 79  SER R CA  1 
ATOM   325  C  C   . SER A 1 200 ? 135.841 142.976 120.727 1.00 40.15  ? 79  SER R C   1 
ATOM   326  O  O   . SER A 1 200 ? 135.471 143.539 119.688 1.00 40.39  ? 79  SER R O   1 
ATOM   327  C  CB  . SER A 1 200 ? 138.268 143.074 121.348 1.00 38.97  ? 79  SER R CB  1 
ATOM   328  O  OG  . SER A 1 200 ? 139.174 143.471 122.353 1.00 44.07  ? 79  SER R OG  1 
ATOM   329  N  N   . LEU A 1 201 ? 135.365 141.785 121.094 1.00 42.08  ? 80  LEU R N   1 
ATOM   330  C  CA  . LEU A 1 201 ? 134.325 141.135 120.305 1.00 40.50  ? 80  LEU R CA  1 
ATOM   331  C  C   . LEU A 1 201 ? 133.042 141.954 120.311 1.00 46.23  ? 80  LEU R C   1 
ATOM   332  O  O   . LEU A 1 201 ? 132.349 142.046 119.290 1.00 52.42  ? 80  LEU R O   1 
ATOM   333  C  CB  . LEU A 1 201 ? 134.071 139.725 120.834 1.00 40.49  ? 80  LEU R CB  1 
ATOM   334  C  CG  . LEU A 1 201 ? 132.998 138.888 120.140 1.00 39.62  ? 80  LEU R CG  1 
ATOM   335  C  CD1 . LEU A 1 201 ? 133.328 138.698 118.679 1.00 37.32  ? 80  LEU R CD1 1 
ATOM   336  C  CD2 . LEU A 1 201 ? 132.854 137.553 120.830 1.00 38.28  ? 80  LEU R CD2 1 
ATOM   337  N  N   . ALA A 1 202 ? 132.708 142.557 121.455 1.00 43.43  ? 81  ALA R N   1 
ATOM   338  C  CA  . ALA A 1 202 ? 131.536 143.425 121.516 1.00 43.94  ? 81  ALA R CA  1 
ATOM   339  C  C   . ALA A 1 202 ? 131.696 144.631 120.600 1.00 45.00  ? 81  ALA R C   1 
ATOM   340  O  O   . ALA A 1 202 ? 130.748 145.030 119.912 1.00 44.71  ? 81  ALA R O   1 
ATOM   341  C  CB  . ALA A 1 202 ? 131.289 143.870 122.956 1.00 46.94  ? 81  ALA R CB  1 
ATOM   342  N  N   . VAL A 1 203 ? 132.893 145.218 120.571 1.00 47.22  ? 82  VAL R N   1 
ATOM   343  C  CA  . VAL A 1 203 ? 133.140 146.351 119.680 1.00 47.71  ? 82  VAL R CA  1 
ATOM   344  C  C   . VAL A 1 203 ? 132.979 145.934 118.223 1.00 49.47  ? 82  VAL R C   1 
ATOM   345  O  O   . VAL A 1 203 ? 132.398 146.667 117.416 1.00 51.92  ? 82  VAL R O   1 
ATOM   346  C  CB  . VAL A 1 203 ? 134.532 146.950 119.942 1.00 46.51  ? 82  VAL R CB  1 
ATOM   347  C  CG1 . VAL A 1 203 ? 134.831 148.034 118.932 1.00 44.42  ? 82  VAL R CG1 1 
ATOM   348  C  CG2 . VAL A 1 203 ? 134.611 147.505 121.344 1.00 49.49  ? 82  VAL R CG2 1 
ATOM   349  N  N   . ALA A 1 204 ? 133.504 144.760 117.860 1.00 51.27  ? 83  ALA R N   1 
ATOM   350  C  CA  . ALA A 1 204 ? 133.403 144.293 116.477 1.00 44.84  ? 83  ALA R CA  1 
ATOM   351  C  C   . ALA A 1 204 ? 131.955 144.031 116.073 1.00 44.54  ? 83  ALA R C   1 
ATOM   352  O  O   . ALA A 1 204 ? 131.542 144.369 114.956 1.00 48.93  ? 83  ALA R O   1 
ATOM   353  C  CB  . ALA A 1 204 ? 134.246 143.036 116.289 1.00 44.26  ? 83  ALA R CB  1 
ATOM   354  N  N   . ASP A 1 205 ? 131.169 143.423 116.965 1.00 44.36  ? 84  ASP R N   1 
ATOM   355  C  CA  . ASP A 1 205 ? 129.749 143.219 116.683 1.00 47.87  ? 84  ASP R CA  1 
ATOM   356  C  C   . ASP A 1 205 ? 129.021 144.547 116.506 1.00 53.92  ? 84  ASP R C   1 
ATOM   357  O  O   . ASP A 1 205 ? 128.200 144.707 115.586 1.00 54.47  ? 84  ASP R O   1 
ATOM   358  C  CB  . ASP A 1 205 ? 129.106 142.419 117.811 1.00 48.05  ? 84  ASP R CB  1 
ATOM   359  C  CG  . ASP A 1 205 ? 129.715 141.048 117.975 1.00 54.42  ? 84  ASP R CG  1 
ATOM   360  O  OD1 . ASP A 1 205 ? 130.297 140.530 117.001 1.00 54.89  ? 84  ASP R OD1 1 
ATOM   361  O  OD2 . ASP A 1 205 ? 129.601 140.481 119.080 1.00 56.06  ? 84  ASP R OD2 1 
ATOM   362  N  N   . MET A 1 206 ? 129.308 145.510 117.384 1.00 56.83  ? 85  MET R N   1 
ATOM   363  C  CA  . MET A 1 206 ? 128.697 146.828 117.277 1.00 52.17  ? 85  MET R CA  1 
ATOM   364  C  C   . MET A 1 206 ? 129.053 147.494 115.955 1.00 53.15  ? 85  MET R C   1 
ATOM   365  O  O   . MET A 1 206 ? 128.198 148.111 115.313 1.00 59.99  ? 85  MET R O   1 
ATOM   366  C  CB  . MET A 1 206 ? 129.146 147.687 118.456 1.00 54.47  ? 85  MET R CB  1 
ATOM   367  C  CG  . MET A 1 206 ? 128.350 148.941 118.666 1.00 57.46  ? 85  MET R CG  1 
ATOM   368  S  SD  . MET A 1 206 ? 129.082 150.037 119.892 1.00 70.36  ? 85  MET R SD  1 
ATOM   369  C  CE  . MET A 1 206 ? 130.037 148.884 120.868 1.00 57.42  ? 85  MET R CE  1 
ATOM   370  N  N   . LEU A 1 207 ? 130.315 147.384 115.538 1.00 53.31  ? 86  LEU R N   1 
ATOM   371  C  CA  . LEU A 1 207 ? 130.740 147.971 114.273 1.00 53.77  ? 86  LEU R CA  1 
ATOM   372  C  C   . LEU A 1 207 ? 130.028 147.329 113.091 1.00 57.04  ? 86  LEU R C   1 
ATOM   373  O  O   . LEU A 1 207 ? 129.593 148.028 112.167 1.00 60.68  ? 86  LEU R O   1 
ATOM   374  C  CB  . LEU A 1 207 ? 132.253 147.838 114.119 1.00 55.58  ? 86  LEU R CB  1 
ATOM   375  C  CG  . LEU A 1 207 ? 132.910 148.705 113.050 1.00 57.86  ? 86  LEU R CG  1 
ATOM   376  C  CD1 . LEU A 1 207 ? 132.606 150.173 113.289 1.00 57.48  ? 86  LEU R CD1 1 
ATOM   377  C  CD2 . LEU A 1 207 ? 134.409 148.458 113.012 1.00 59.63  ? 86  LEU R CD2 1 
ATOM   378  N  N   . VAL A 1 208 ? 129.897 145.999 113.100 1.00 57.89  ? 87  VAL R N   1 
ATOM   379  C  CA  . VAL A 1 208 ? 129.174 145.317 112.026 1.00 57.25  ? 87  VAL R CA  1 
ATOM   380  C  C   . VAL A 1 208 ? 127.755 145.861 111.919 1.00 60.18  ? 87  VAL R C   1 
ATOM   381  O  O   . VAL A 1 208 ? 127.293 146.247 110.834 1.00 58.33  ? 87  VAL R O   1 
ATOM   382  C  CB  . VAL A 1 208 ? 129.165 143.795 112.263 1.00 56.87  ? 87  VAL R CB  1 
ATOM   383  C  CG1 . VAL A 1 208 ? 128.020 143.152 111.508 1.00 59.84  ? 87  VAL R CG1 1 
ATOM   384  C  CG2 . VAL A 1 208 ? 130.470 143.171 111.845 1.00 57.78  ? 87  VAL R CG2 1 
ATOM   385  N  N   . SER A 1 209 ? 127.049 145.916 113.054 1.00 63.76  ? 88  SER R N   1 
ATOM   386  C  CA  . SER A 1 209 ? 125.654 146.350 113.030 1.00 63.89  ? 88  SER R CA  1 
ATOM   387  C  C   . SER A 1 209 ? 125.516 147.808 112.610 1.00 65.29  ? 88  SER R C   1 
ATOM   388  O  O   . SER A 1 209 ? 124.634 148.147 111.812 1.00 66.04  ? 88  SER R O   1 
ATOM   389  C  CB  . SER A 1 209 ? 125.015 146.139 114.393 1.00 62.84  ? 88  SER R CB  1 
ATOM   390  O  OG  . SER A 1 209 ? 124.506 144.825 114.517 1.00 65.44  ? 88  SER R OG  1 
ATOM   391  N  N   . VAL A 1 210 ? 126.364 148.687 113.148 1.00 65.65  ? 89  VAL R N   1 
ATOM   392  C  CA  . VAL A 1 210 ? 126.278 150.104 112.811 1.00 63.76  ? 89  VAL R CA  1 
ATOM   393  C  C   . VAL A 1 210 ? 126.530 150.310 111.325 1.00 67.98  ? 89  VAL R C   1 
ATOM   394  O  O   . VAL A 1 210 ? 125.793 151.040 110.650 1.00 70.56  ? 89  VAL R O   1 
ATOM   395  C  CB  . VAL A 1 210 ? 127.260 150.922 113.669 1.00 65.34  ? 89  VAL R CB  1 
ATOM   396  C  CG1 . VAL A 1 210 ? 127.656 152.202 112.958 1.00 68.78  ? 89  VAL R CG1 1 
ATOM   397  C  CG2 . VAL A 1 210 ? 126.646 151.242 115.005 1.00 66.27  ? 89  VAL R CG2 1 
ATOM   398  N  N   . SER A 1 211 ? 127.571 149.665 110.789 1.00 66.20  ? 90  SER R N   1 
ATOM   399  C  CA  . SER A 1 211 ? 127.893 149.839 109.379 1.00 65.68  ? 90  SER R CA  1 
ATOM   400  C  C   . SER A 1 211 ? 126.748 149.367 108.496 1.00 69.11  ? 90  SER R C   1 
ATOM   401  O  O   . SER A 1 211 ? 126.343 150.066 107.557 1.00 68.46  ? 90  SER R O   1 
ATOM   402  C  CB  . SER A 1 211 ? 129.176 149.086 109.044 1.00 65.27  ? 90  SER R CB  1 
ATOM   403  O  OG  . SER A 1 211 ? 130.276 149.646 109.733 1.00 68.14  ? 90  SER R OG  1 
ATOM   404  N  N   . ASN A 1 212 ? 126.196 148.186 108.794 1.00 73.42  ? 91  ASN R N   1 
ATOM   405  C  CA  . ASN A 1 212 ? 125.126 147.661 107.953 1.00 70.71  ? 91  ASN R CA  1 
ATOM   406  C  C   . ASN A 1 212 ? 123.871 148.521 108.042 1.00 71.86  ? 91  ASN R C   1 
ATOM   407  O  O   . ASN A 1 212 ? 123.223 148.780 107.023 1.00 72.20  ? 91  ASN R O   1 
ATOM   408  C  CB  . ASN A 1 212 ? 124.824 146.214 108.327 1.00 69.19  ? 91  ASN R CB  1 
ATOM   409  C  CG  . ASN A 1 212 ? 125.674 145.230 107.555 1.00 72.02  ? 91  ASN R CG  1 
ATOM   410  O  OD1 . ASN A 1 212 ? 125.388 144.918 106.400 1.00 71.61  ? 91  ASN R OD1 1 
ATOM   411  N  ND2 . ASN A 1 212 ? 126.730 144.738 108.187 1.00 70.61  ? 91  ASN R ND2 1 
ATOM   412  N  N   . ALA A 1 213 ? 123.516 148.989 109.243 1.00 76.68  ? 92  ALA R N   1 
ATOM   413  C  CA  . ALA A 1 213 ? 122.322 149.819 109.384 1.00 77.39  ? 92  ALA R CA  1 
ATOM   414  C  C   . ALA A 1 213 ? 122.479 151.162 108.676 1.00 78.42  ? 92  ALA R C   1 
ATOM   415  O  O   . ALA A 1 213 ? 121.539 151.645 108.031 1.00 78.78  ? 92  ALA R O   1 
ATOM   416  C  CB  . ALA A 1 213 ? 122.000 150.025 110.862 1.00 75.45  ? 92  ALA R CB  1 
ATOM   417  N  N   . LEU A 1 214 ? 123.655 151.785 108.786 1.00 77.69  ? 93  LEU R N   1 
ATOM   418  C  CA  . LEU A 1 214 ? 123.879 153.053 108.099 1.00 77.29  ? 93  LEU R CA  1 
ATOM   419  C  C   . LEU A 1 214 ? 123.835 152.878 106.587 1.00 77.16  ? 93  LEU R C   1 
ATOM   420  O  O   . LEU A 1 214 ? 123.244 153.701 105.873 1.00 79.54  ? 93  LEU R O   1 
ATOM   421  C  CB  . LEU A 1 214 ? 125.215 153.653 108.532 1.00 79.51  ? 93  LEU R CB  1 
ATOM   422  C  CG  . LEU A 1 214 ? 125.197 154.689 109.657 1.00 78.62  ? 93  LEU R CG  1 
ATOM   423  C  CD1 . LEU A 1 214 ? 124.197 154.321 110.736 1.00 76.73  ? 93  LEU R CD1 1 
ATOM   424  C  CD2 . LEU A 1 214 ? 126.588 154.823 110.250 1.00 77.76  ? 93  LEU R CD2 1 
ATOM   425  N  N   . GLU A 1 215 ? 124.449 151.810 106.073 1.00 76.51  ? 94  GLU R N   1 
ATOM   426  C  CA  . GLU A 1 215 ? 124.360 151.562 104.640 1.00 78.57  ? 94  GLU R CA  1 
ATOM   427  C  C   . GLU A 1 215 ? 122.927 151.271 104.214 1.00 80.44  ? 94  GLU R C   1 
ATOM   428  O  O   . GLU A 1 215 ? 122.524 151.633 103.105 1.00 80.11  ? 94  GLU R O   1 
ATOM   429  C  CB  . GLU A 1 215 ? 125.284 150.414 104.244 1.00 79.74  ? 94  GLU R CB  1 
ATOM   430  C  CG  . GLU A 1 215 ? 125.776 150.489 102.817 1.00 77.66  ? 94  GLU R CG  1 
ATOM   431  C  CD  . GLU A 1 215 ? 126.275 149.160 102.321 1.00 76.34  ? 94  GLU R CD  1 
ATOM   432  O  OE1 . GLU A 1 215 ? 126.143 148.170 103.064 1.00 78.79  ? 94  GLU R OE1 1 
ATOM   433  O  OE2 . GLU A 1 215 ? 126.800 149.101 101.192 1.00 74.22  ? 94  GLU R OE2 1 
ATOM   434  N  N   . THR A 1 216 ? 122.137 150.634 105.081 1.00 83.20  ? 95  THR R N   1 
ATOM   435  C  CA  . THR A 1 216 ? 120.732 150.406 104.763 1.00 83.47  ? 95  THR R CA  1 
ATOM   436  C  C   . THR A 1 216 ? 119.962 151.716 104.657 1.00 85.81  ? 95  THR R C   1 
ATOM   437  O  O   . THR A 1 216 ? 119.164 151.897 103.729 1.00 85.25  ? 95  THR R O   1 
ATOM   438  C  CB  . THR A 1 216 ? 120.094 149.504 105.815 1.00 83.37  ? 95  THR R CB  1 
ATOM   439  O  OG1 . THR A 1 216 ? 121.050 148.532 106.254 1.00 85.05  ? 95  THR R OG1 1 
ATOM   440  C  CG2 . THR A 1 216 ? 118.889 148.792 105.237 1.00 84.17  ? 95  THR R CG2 1 
ATOM   441  N  N   . ILE A 1 217 ? 120.175 152.639 105.601 1.00 92.05  ? 96  ILE R N   1 
ATOM   442  C  CA  . ILE A 1 217 ? 119.463 153.914 105.514 1.00 91.48  ? 96  ILE R CA  1 
ATOM   443  C  C   . ILE A 1 217 ? 119.914 154.694 104.287 1.00 91.64  ? 96  ILE R C   1 
ATOM   444  O  O   . ILE A 1 217 ? 119.105 155.385 103.657 1.00 91.36  ? 96  ILE R O   1 
ATOM   445  C  CB  . ILE A 1 217 ? 119.606 154.758 106.800 1.00 90.93  ? 96  ILE R CB  1 
ATOM   446  C  CG1 . ILE A 1 217 ? 120.941 155.504 106.847 1.00 90.99  ? 96  ILE R CG1 1 
ATOM   447  C  CG2 . ILE A 1 217 ? 119.412 153.908 108.032 1.00 90.34  ? 96  ILE R CG2 1 
ATOM   448  C  CD1 . ILE A 1 217 ? 121.025 156.538 107.946 1.00 90.58  ? 96  ILE R CD1 1 
ATOM   449  N  N   . MET A 1 218 ? 121.193 154.595 103.913 1.00 94.27  ? 97  MET R N   1 
ATOM   450  C  CA  . MET A 1 218 ? 121.641 155.301 102.717 1.00 92.92  ? 97  MET R CA  1 
ATOM   451  C  C   . MET A 1 218 ? 121.049 154.683 101.454 1.00 94.62  ? 97  MET R C   1 
ATOM   452  O  O   . MET A 1 218 ? 120.701 155.402 100.511 1.00 95.07  ? 97  MET R O   1 
ATOM   453  C  CB  . MET A 1 218 ? 123.165 155.317 102.645 1.00 91.65  ? 97  MET R CB  1 
ATOM   454  C  CG  . MET A 1 218 ? 123.691 156.017 101.411 1.00 93.09  ? 97  MET R CG  1 
ATOM   455  S  SD  . MET A 1 218 ? 124.170 157.720 101.746 1.00 96.94  ? 97  MET R SD  1 
ATOM   456  C  CE  . MET A 1 218 ? 125.331 158.011 100.415 1.00 94.49  ? 97  MET R CE  1 
ATOM   457  N  N   . ILE A 1 219 ? 120.925 153.355 101.418 1.00 98.72  ? 98  ILE R N   1 
ATOM   458  C  CA  . ILE A 1 219 ? 120.264 152.695 100.294 1.00 98.69  ? 98  ILE R CA  1 
ATOM   459  C  C   . ILE A 1 219 ? 118.816 153.152 100.192 1.00 98.89  ? 98  ILE R C   1 
ATOM   460  O  O   . ILE A 1 219 ? 118.318 153.465 99.104  1.00 97.21  ? 98  ILE R O   1 
ATOM   461  C  CB  . ILE A 1 219 ? 120.362 151.166 100.436 1.00 98.41  ? 98  ILE R CB  1 
ATOM   462  C  CG1 . ILE A 1 219 ? 121.729 150.677 99.983  1.00 96.85  ? 98  ILE R CG1 1 
ATOM   463  C  CG2 . ILE A 1 219 ? 119.288 150.481 99.611  1.00 98.90  ? 98  ILE R CG2 1 
ATOM   464  C  CD1 . ILE A 1 219 ? 121.999 151.008 98.553  1.00 97.24  ? 98  ILE R CD1 1 
ATOM   465  N  N   . ALA A 1 220 ? 118.118 153.199 101.328 1.00 105.90 ? 99  ALA R N   1 
ATOM   466  C  CA  . ALA A 1 220 ? 116.712 153.585 101.311 1.00 106.09 ? 99  ALA R CA  1 
ATOM   467  C  C   . ALA A 1 220 ? 116.528 155.051 100.935 1.00 106.93 ? 99  ALA R C   1 
ATOM   468  O  O   . ALA A 1 220 ? 115.528 155.402 100.298 1.00 106.28 ? 99  ALA R O   1 
ATOM   469  C  CB  . ALA A 1 220 ? 116.073 153.299 102.669 1.00 104.59 ? 99  ALA R CB  1 
ATOM   470  N  N   . ILE A 1 221 ? 117.473 155.919 101.312 1.00 105.78 ? 100 ILE R N   1 
ATOM   471  C  CA  . ILE A 1 221 ? 117.321 157.347 101.039 1.00 104.92 ? 100 ILE R CA  1 
ATOM   472  C  C   . ILE A 1 221 ? 117.318 157.606 99.537  1.00 106.78 ? 100 ILE R C   1 
ATOM   473  O  O   . ILE A 1 221 ? 116.453 158.319 99.016  1.00 106.95 ? 100 ILE R O   1 
ATOM   474  C  CB  . ILE A 1 221 ? 118.421 158.153 101.754 1.00 104.44 ? 100 ILE R CB  1 
ATOM   475  C  CG1 . ILE A 1 221 ? 117.990 158.484 103.183 1.00 104.96 ? 100 ILE R CG1 1 
ATOM   476  C  CG2 . ILE A 1 221 ? 118.717 159.439 101.012 1.00 105.77 ? 100 ILE R CG2 1 
ATOM   477  C  CD1 . ILE A 1 221 ? 119.008 159.291 103.954 1.00 104.83 ? 100 ILE R CD1 1 
ATOM   478  N  N   . VAL A 1 222 ? 118.274 157.024 98.814  1.00 111.51 ? 101 VAL R N   1 
ATOM   479  C  CA  . VAL A 1 222 ? 118.290 157.162 97.361  1.00 111.32 ? 101 VAL R CA  1 
ATOM   480  C  C   . VAL A 1 222 ? 117.907 155.832 96.710  1.00 111.30 ? 101 VAL R C   1 
ATOM   481  O  O   . VAL A 1 222 ? 118.682 154.870 96.685  1.00 111.62 ? 101 VAL R O   1 
ATOM   482  C  CB  . VAL A 1 222 ? 119.640 157.738 96.863  1.00 110.75 ? 101 VAL R CB  1 
ATOM   483  C  CG1 . VAL A 1 222 ? 120.067 158.886 97.755  1.00 110.88 ? 101 VAL R CG1 1 
ATOM   484  C  CG2 . VAL A 1 222 ? 120.775 156.716 96.846  1.00 109.69 ? 101 VAL R CG2 1 
ATOM   485  N  N   . HIS A 1 223 ? 116.661 155.746 96.252  1.00 115.65 ? 102 HIS R N   1 
ATOM   486  C  CA  . HIS A 1 223 ? 116.224 154.590 95.481  1.00 115.80 ? 102 HIS R CA  1 
ATOM   487  C  C   . HIS A 1 223 ? 115.529 155.027 94.198  1.00 115.98 ? 102 HIS R C   1 
ATOM   488  O  O   . HIS A 1 223 ? 115.697 154.396 93.149  1.00 115.70 ? 102 HIS R O   1 
ATOM   489  C  CB  . HIS A 1 223 ? 115.306 153.699 96.323  1.00 115.13 ? 102 HIS R CB  1 
ATOM   490  C  CG  . HIS A 1 223 ? 114.096 154.403 96.852  1.00 115.98 ? 102 HIS R CG  1 
ATOM   491  N  ND1 . HIS A 1 223 ? 114.156 155.304 97.893  1.00 115.26 ? 102 HIS R ND1 1 
ATOM   492  C  CD2 . HIS A 1 223 ? 112.794 154.332 96.490  1.00 116.15 ? 102 HIS R CD2 1 
ATOM   493  C  CE1 . HIS A 1 223 ? 112.943 155.762 98.146  1.00 115.73 ? 102 HIS R CE1 1 
ATOM   494  N  NE2 . HIS A 1 223 ? 112.098 155.187 97.309  1.00 116.32 ? 102 HIS R NE2 1 
ATOM   495  N  N   . SER A 1 224 ? 114.749 156.099 94.270  1.00 125.02 ? 103 SER R N   1 
ATOM   496  C  CA  . SER A 1 224 ? 114.074 156.627 93.089  1.00 126.03 ? 103 SER R CA  1 
ATOM   497  C  C   . SER A 1 224 ? 114.244 158.128 92.911  1.00 126.11 ? 103 SER R C   1 
ATOM   498  O  O   . SER A 1 224 ? 114.393 158.590 91.777  1.00 124.92 ? 103 SER R O   1 
ATOM   499  C  CB  . SER A 1 224 ? 112.576 156.282 93.141  1.00 124.98 ? 103 SER R CB  1 
ATOM   500  O  OG  . SER A 1 224 ? 112.374 154.879 93.150  1.00 124.03 ? 103 SER R OG  1 
ATOM   501  N  N   . ASP A 1 225 ? 114.237 158.899 93.996  1.00 127.13 ? 104 ASP R N   1 
ATOM   502  C  CA  . ASP A 1 225 ? 114.210 160.352 93.914  1.00 126.47 ? 104 ASP R CA  1 
ATOM   503  C  C   . ASP A 1 225 ? 115.256 160.954 94.841  1.00 127.26 ? 104 ASP R C   1 
ATOM   504  O  O   . ASP A 1 225 ? 115.827 160.272 95.696  1.00 126.70 ? 104 ASP R O   1 
ATOM   505  C  CB  . ASP A 1 225 ? 112.823 160.908 94.265  1.00 125.91 ? 104 ASP R CB  1 
ATOM   506  C  CG  . ASP A 1 225 ? 112.183 160.183 95.430  1.00 126.26 ? 104 ASP R CG  1 
ATOM   507  O  OD1 . ASP A 1 225 ? 112.611 159.051 95.735  1.00 125.79 ? 104 ASP R OD1 1 
ATOM   508  O  OD2 . ASP A 1 225 ? 111.253 160.746 96.044  1.00 126.51 ? 104 ASP R OD2 1 
ATOM   509  N  N   . TYR A 1 226 ? 115.493 162.254 94.652  1.00 127.31 ? 105 TYR R N   1 
ATOM   510  C  CA  . TYR A 1 226 ? 116.467 163.024 95.427  1.00 127.30 ? 105 TYR R CA  1 
ATOM   511  C  C   . TYR A 1 226 ? 117.869 162.421 95.305  1.00 127.74 ? 105 TYR R C   1 
ATOM   512  O  O   . TYR A 1 226 ? 118.461 161.936 96.272  1.00 127.90 ? 105 TYR R O   1 
ATOM   513  C  CB  . TYR A 1 226 ? 116.040 163.145 96.895  1.00 126.56 ? 105 TYR R CB  1 
ATOM   514  C  CG  . TYR A 1 226 ? 116.974 164.002 97.719  1.00 126.72 ? 105 TYR R CG  1 
ATOM   515  C  CD1 . TYR A 1 226 ? 117.336 165.274 97.295  1.00 126.77 ? 105 TYR R CD1 1 
ATOM   516  C  CD2 . TYR A 1 226 ? 117.506 163.534 98.912  1.00 126.55 ? 105 TYR R CD2 1 
ATOM   517  C  CE1 . TYR A 1 226 ? 118.195 166.060 98.040  1.00 127.13 ? 105 TYR R CE1 1 
ATOM   518  C  CE2 . TYR A 1 226 ? 118.366 164.313 99.665  1.00 127.32 ? 105 TYR R CE2 1 
ATOM   519  C  CZ  . TYR A 1 226 ? 118.706 165.575 99.224  1.00 127.61 ? 105 TYR R CZ  1 
ATOM   520  O  OH  . TYR A 1 226 ? 119.561 166.354 99.969  1.00 126.51 ? 105 TYR R OH  1 
ATOM   521  N  N   . LEU A 1 227 ? 118.388 162.451 94.082  1.00 124.54 ? 106 LEU R N   1 
ATOM   522  C  CA  . LEU A 1 227 ? 119.746 161.990 93.837  1.00 124.96 ? 106 LEU R CA  1 
ATOM   523  C  C   . LEU A 1 227 ? 120.755 162.942 94.467  1.00 125.36 ? 106 LEU R C   1 
ATOM   524  O  O   . LEU A 1 227 ? 120.595 164.165 94.419  1.00 124.66 ? 106 LEU R O   1 
ATOM   525  C  CB  . LEU A 1 227 ? 120.005 161.875 92.335  1.00 124.85 ? 106 LEU R CB  1 
ATOM   526  C  CG  . LEU A 1 227 ? 121.404 161.420 91.917  1.00 124.79 ? 106 LEU R CG  1 
ATOM   527  C  CD1 . LEU A 1 227 ? 121.435 159.914 91.725  1.00 124.02 ? 106 LEU R CD1 1 
ATOM   528  C  CD2 . LEU A 1 227 ? 121.848 162.139 90.653  1.00 124.37 ? 106 LEU R CD2 1 
ATOM   529  N  N   . THR A 1 228 ? 121.799 162.372 95.070  1.00 123.86 ? 107 THR R N   1 
ATOM   530  C  CA  . THR A 1 228 ? 122.879 163.185 95.619  1.00 124.69 ? 107 THR R CA  1 
ATOM   531  C  C   . THR A 1 228 ? 123.869 163.579 94.529  1.00 123.42 ? 107 THR R C   1 
ATOM   532  O  O   . THR A 1 228 ? 124.059 164.766 94.243  1.00 122.75 ? 107 THR R O   1 
ATOM   533  C  CB  . THR A 1 228 ? 123.588 162.428 96.745  1.00 123.71 ? 107 THR R CB  1 
ATOM   534  O  OG1 . THR A 1 228 ? 124.103 161.190 96.239  1.00 123.01 ? 107 THR R OG1 1 
ATOM   535  C  CG2 . THR A 1 228 ? 122.622 162.144 97.886  1.00 122.06 ? 107 THR R CG2 1 
ATOM   536  N  N   . PHE A 1 229 ? 124.507 162.589 93.910  1.00 123.09 ? 108 PHE R N   1 
ATOM   537  C  CA  . PHE A 1 229 ? 125.386 162.809 92.773  1.00 123.20 ? 108 PHE R CA  1 
ATOM   538  C  C   . PHE A 1 229 ? 125.194 161.663 91.794  1.00 123.51 ? 108 PHE R C   1 
ATOM   539  O  O   . PHE A 1 229 ? 124.621 160.624 92.130  1.00 123.55 ? 108 PHE R O   1 
ATOM   540  C  CB  . PHE A 1 229 ? 126.857 162.920 93.191  1.00 124.43 ? 108 PHE R CB  1 
ATOM   541  C  CG  . PHE A 1 229 ? 127.735 163.562 92.152  1.00 124.39 ? 108 PHE R CG  1 
ATOM   542  C  CD1 . PHE A 1 229 ? 127.655 164.923 91.905  1.00 123.72 ? 108 PHE R CD1 1 
ATOM   543  C  CD2 . PHE A 1 229 ? 128.636 162.804 91.421  1.00 123.62 ? 108 PHE R CD2 1 
ATOM   544  C  CE1 . PHE A 1 229 ? 128.459 165.517 90.950  1.00 123.35 ? 108 PHE R CE1 1 
ATOM   545  C  CE2 . PHE A 1 229 ? 129.442 163.392 90.464  1.00 123.09 ? 108 PHE R CE2 1 
ATOM   546  C  CZ  . PHE A 1 229 ? 129.353 164.750 90.228  1.00 123.22 ? 108 PHE R CZ  1 
ATOM   547  N  N   . GLU A 1 230 ? 125.678 161.861 90.568  1.00 123.95 ? 109 GLU R N   1 
ATOM   548  C  CA  . GLU A 1 230 ? 125.372 160.913 89.503  1.00 124.39 ? 109 GLU R CA  1 
ATOM   549  C  C   . GLU A 1 230 ? 126.181 159.628 89.647  1.00 124.42 ? 109 GLU R C   1 
ATOM   550  O  O   . GLU A 1 230 ? 125.618 158.548 89.857  1.00 123.83 ? 109 GLU R O   1 
ATOM   551  C  CB  . GLU A 1 230 ? 125.619 161.561 88.140  1.00 123.04 ? 109 GLU R CB  1 
ATOM   552  C  CG  . GLU A 1 230 ? 124.575 161.208 87.096  1.00 122.86 ? 109 GLU R CG  1 
ATOM   553  C  CD  . GLU A 1 230 ? 124.960 159.993 86.274  1.00 123.13 ? 109 GLU R CD  1 
ATOM   554  O  OE1 . GLU A 1 230 ? 126.125 159.920 85.829  1.00 123.82 ? 109 GLU R OE1 1 
ATOM   555  O  OE2 . GLU A 1 230 ? 124.100 159.109 86.076  1.00 123.06 ? 109 GLU R OE2 1 
ATOM   556  N  N   . ASP A 1 231 ? 127.509 159.721 89.540  1.00 121.36 ? 110 ASP R N   1 
ATOM   557  C  CA  . ASP A 1 231 ? 128.324 158.516 89.477  1.00 122.08 ? 110 ASP R CA  1 
ATOM   558  C  C   . ASP A 1 231 ? 129.659 158.591 90.204  1.00 122.00 ? 110 ASP R C   1 
ATOM   559  O  O   . ASP A 1 231 ? 130.474 157.679 90.032  1.00 122.17 ? 110 ASP R O   1 
ATOM   560  C  CB  . ASP A 1 231 ? 128.579 158.134 88.009  1.00 121.16 ? 110 ASP R CB  1 
ATOM   561  C  CG  . ASP A 1 231 ? 127.486 157.253 87.437  1.00 121.24 ? 110 ASP R CG  1 
ATOM   562  O  OD1 . ASP A 1 231 ? 126.818 156.545 88.220  1.00 120.62 ? 110 ASP R OD1 1 
ATOM   563  O  OD2 . ASP A 1 231 ? 127.295 157.269 86.203  1.00 120.69 ? 110 ASP R OD2 1 
ATOM   564  N  N   . GLN A 1 232 ? 129.925 159.627 90.994  1.00 119.48 ? 111 GLN R N   1 
ATOM   565  C  CA  . GLN A 1 232 ? 131.224 159.758 91.646  1.00 120.34 ? 111 GLN R CA  1 
ATOM   566  C  C   . GLN A 1 232 ? 131.151 159.777 93.164  1.00 119.85 ? 111 GLN R C   1 
ATOM   567  O  O   . GLN A 1 232 ? 131.942 159.097 93.819  1.00 120.05 ? 111 GLN R O   1 
ATOM   568  C  CB  . GLN A 1 232 ? 131.934 161.026 91.159  1.00 119.89 ? 111 GLN R CB  1 
ATOM   569  C  CG  . GLN A 1 232 ? 133.437 161.028 91.388  1.00 119.43 ? 111 GLN R CG  1 
ATOM   570  C  CD  . GLN A 1 232 ? 133.909 162.251 92.149  1.00 120.34 ? 111 GLN R CD  1 
ATOM   571  O  OE1 . GLN A 1 232 ? 133.178 163.231 92.286  1.00 120.54 ? 111 GLN R OE1 1 
ATOM   572  N  NE2 . GLN A 1 232 ? 135.142 162.202 92.640  1.00 119.92 ? 111 GLN R NE2 1 
ATOM   573  N  N   . PHE A 1 233 ? 130.228 160.544 93.746  1.00 116.99 ? 112 PHE R N   1 
ATOM   574  C  CA  . PHE A 1 233 ? 130.139 160.611 95.201  1.00 117.80 ? 112 PHE R CA  1 
ATOM   575  C  C   . PHE A 1 233 ? 129.521 159.342 95.776  1.00 118.86 ? 112 PHE R C   1 
ATOM   576  O  O   . PHE A 1 233 ? 129.935 158.868 96.845  1.00 118.18 ? 112 PHE R O   1 
ATOM   577  C  CB  . PHE A 1 233 ? 129.333 161.841 95.612  1.00 117.07 ? 112 PHE R CB  1 
ATOM   578  C  CG  . PHE A 1 233 ? 129.050 161.919 97.081  1.00 118.26 ? 112 PHE R CG  1 
ATOM   579  C  CD1 . PHE A 1 233 ? 130.063 162.199 97.981  1.00 117.71 ? 112 PHE R CD1 1 
ATOM   580  C  CD2 . PHE A 1 233 ? 127.767 161.718 97.562  1.00 117.82 ? 112 PHE R CD2 1 
ATOM   581  C  CE1 . PHE A 1 233 ? 129.804 162.274 99.334  1.00 116.70 ? 112 PHE R CE1 1 
ATOM   582  C  CE2 . PHE A 1 233 ? 127.502 161.792 98.912  1.00 117.78 ? 112 PHE R CE2 1 
ATOM   583  C  CZ  . PHE A 1 233 ? 128.522 162.071 99.800  1.00 117.09 ? 112 PHE R CZ  1 
ATOM   584  N  N   . ILE A 1 234 ? 128.533 158.775 95.079  1.00 116.66 ? 113 ILE R N   1 
ATOM   585  C  CA  . ILE A 1 234 ? 127.887 157.561 95.561  1.00 115.87 ? 113 ILE R CA  1 
ATOM   586  C  C   . ILE A 1 234 ? 128.873 156.399 95.587  1.00 114.72 ? 113 ILE R C   1 
ATOM   587  O  O   . ILE A 1 234 ? 128.830 155.560 96.494  1.00 114.30 ? 113 ILE R O   1 
ATOM   588  C  CB  . ILE A 1 234 ? 126.639 157.251 94.710  1.00 115.42 ? 113 ILE R CB  1 
ATOM   589  C  CG1 . ILE A 1 234 ? 125.829 156.118 95.338  1.00 115.28 ? 113 ILE R CG1 1 
ATOM   590  C  CG2 . ILE A 1 234 ? 127.011 156.938 93.270  1.00 114.67 ? 113 ILE R CG2 1 
ATOM   591  C  CD1 . ILE A 1 234 ? 125.589 156.305 96.811  1.00 115.36 ? 113 ILE R CD1 1 
ATOM   592  N  N   . GLN A 1 235 ? 129.789 156.339 94.617  1.00 109.17 ? 114 GLN R N   1 
ATOM   593  C  CA  . GLN A 1 235 ? 130.823 155.310 94.635  1.00 109.33 ? 114 GLN R CA  1 
ATOM   594  C  C   . GLN A 1 235 ? 131.729 155.460 95.850  1.00 109.39 ? 114 GLN R C   1 
ATOM   595  O  O   . GLN A 1 235 ? 132.093 154.467 96.494  1.00 109.08 ? 114 GLN R O   1 
ATOM   596  C  CB  . GLN A 1 235 ? 131.640 155.374 93.346  1.00 108.08 ? 114 GLN R CB  1 
ATOM   597  C  CG  . GLN A 1 235 ? 132.846 154.461 93.330  1.00 109.57 ? 114 GLN R CG  1 
ATOM   598  C  CD  . GLN A 1 235 ? 133.245 154.069 91.926  1.00 110.64 ? 114 GLN R CD  1 
ATOM   599  O  OE1 . GLN A 1 235 ? 132.607 154.473 90.956  1.00 110.68 ? 114 GLN R OE1 1 
ATOM   600  N  NE2 . GLN A 1 235 ? 134.301 153.273 91.809  1.00 110.04 ? 114 GLN R NE2 1 
ATOM   601  N  N   . HIS A 1 236 ? 132.104 156.698 96.178  1.00 108.34 ? 115 HIS R N   1 
ATOM   602  C  CA  . HIS A 1 236 ? 132.944 156.929 97.347  1.00 108.26 ? 115 HIS R CA  1 
ATOM   603  C  C   . HIS A 1 236 ? 132.236 156.505 98.625  1.00 106.67 ? 115 HIS R C   1 
ATOM   604  O  O   . HIS A 1 236 ? 132.836 155.852 99.487  1.00 107.37 ? 115 HIS R O   1 
ATOM   605  C  CB  . HIS A 1 236 ? 133.352 158.400 97.417  1.00 108.53 ? 115 HIS R CB  1 
ATOM   606  C  CG  . HIS A 1 236 ? 134.392 158.784 96.411  1.00 109.02 ? 115 HIS R CG  1 
ATOM   607  N  ND1 . HIS A 1 236 ? 135.596 158.123 96.298  1.00 108.71 ? 115 HIS R ND1 1 
ATOM   608  C  CD2 . HIS A 1 236 ? 134.406 159.756 95.470  1.00 107.53 ? 115 HIS R CD2 1 
ATOM   609  C  CE1 . HIS A 1 236 ? 136.308 158.674 95.331  1.00 107.76 ? 115 HIS R CE1 1 
ATOM   610  N  NE2 . HIS A 1 236 ? 135.608 159.667 94.812  1.00 107.17 ? 115 HIS R NE2 1 
ATOM   611  N  N   . MET A 1 237 ? 130.954 156.852 98.763  1.00 100.34 ? 116 MET R N   1 
ATOM   612  C  CA  . MET A 1 237 ? 130.220 156.445 99.958  1.00 100.56 ? 116 MET R CA  1 
ATOM   613  C  C   . MET A 1 237 ? 130.086 154.928 100.040 1.00 103.30 ? 116 MET R C   1 
ATOM   614  O  O   . MET A 1 237 ? 130.206 154.342 101.126 1.00 103.79 ? 116 MET R O   1 
ATOM   615  C  CB  . MET A 1 237 ? 128.848 157.111 99.982  1.00 100.77 ? 116 MET R CB  1 
ATOM   616  C  CG  . MET A 1 237 ? 128.893 158.573 100.370 1.00 102.97 ? 116 MET R CG  1 
ATOM   617  S  SD  . MET A 1 237 ? 130.156 158.921 101.609 1.00 111.95 ? 116 MET R SD  1 
ATOM   618  C  CE  . MET A 1 237 ? 129.205 159.830 102.826 1.00 102.48 ? 116 MET R CE  1 
ATOM   619  N  N   . ASP A 1 238 ? 129.836 154.275 98.903  1.00 96.95  ? 117 ASP R N   1 
ATOM   620  C  CA  . ASP A 1 238 ? 129.748 152.819 98.886  1.00 92.77  ? 117 ASP R CA  1 
ATOM   621  C  C   . ASP A 1 238 ? 131.050 152.190 99.362  1.00 92.81  ? 117 ASP R C   1 
ATOM   622  O  O   . ASP A 1 238 ? 131.044 151.282 100.202 1.00 95.06  ? 117 ASP R O   1 
ATOM   623  C  CB  . ASP A 1 238 ? 129.396 152.342 97.478  1.00 92.12  ? 117 ASP R CB  1 
ATOM   624  C  CG  . ASP A 1 238 ? 128.940 150.905 97.446  1.00 91.86  ? 117 ASP R CG  1 
ATOM   625  O  OD1 . ASP A 1 238 ? 128.515 150.386 98.497  1.00 92.92  ? 117 ASP R OD1 1 
ATOM   626  O  OD2 . ASP A 1 238 ? 129.001 150.292 96.361  1.00 92.98  ? 117 ASP R OD2 1 
ATOM   627  N  N   . ASN A 1 239 ? 132.181 152.671 98.843  1.00 89.97  ? 118 ASN R N   1 
ATOM   628  C  CA  . ASN A 1 239 ? 133.469 152.155 99.291  1.00 89.79  ? 118 ASN R CA  1 
ATOM   629  C  C   . ASN A 1 239 ? 133.665 152.389 100.784 1.00 89.56  ? 118 ASN R C   1 
ATOM   630  O  O   . ASN A 1 239 ? 134.160 151.510 101.502 1.00 89.09  ? 118 ASN R O   1 
ATOM   631  C  CB  . ASN A 1 239 ? 134.599 152.811 98.501  1.00 90.82  ? 118 ASN R CB  1 
ATOM   632  C  CG  . ASN A 1 239 ? 134.752 152.234 97.117  1.00 90.80  ? 118 ASN R CG  1 
ATOM   633  O  OD1 . ASN A 1 239 ? 133.789 152.149 96.359  1.00 91.21  ? 118 ASN R OD1 1 
ATOM   634  N  ND2 . ASN A 1 239 ? 135.971 151.840 96.773  1.00 91.37  ? 118 ASN R ND2 1 
ATOM   635  N  N   . ILE A 1 240 ? 133.275 153.572 101.266 1.00 90.66  ? 119 ILE R N   1 
ATOM   636  C  CA  . ILE A 1 240 ? 133.493 153.925 102.666 1.00 91.60  ? 119 ILE R CA  1 
ATOM   637  C  C   . ILE A 1 240 ? 132.722 152.987 103.585 1.00 90.18  ? 119 ILE R C   1 
ATOM   638  O  O   . ILE A 1 240 ? 133.238 152.547 104.618 1.00 90.97  ? 119 ILE R O   1 
ATOM   639  C  CB  . ILE A 1 240 ? 133.118 155.399 102.910 1.00 91.40  ? 119 ILE R CB  1 
ATOM   640  C  CG1 . ILE A 1 240 ? 134.148 156.331 102.269 1.00 91.19  ? 119 ILE R CG1 1 
ATOM   641  C  CG2 . ILE A 1 240 ? 133.002 155.687 104.396 1.00 90.41  ? 119 ILE R CG2 1 
ATOM   642  C  CD1 . ILE A 1 240 ? 135.573 155.819 102.320 1.00 89.78  ? 119 ILE R CD1 1 
ATOM   643  N  N   . PHE A 1 241 ? 131.474 152.669 103.235 1.00 80.80  ? 120 PHE R N   1 
ATOM   644  C  CA  . PHE A 1 241 ? 130.710 151.757 104.084 1.00 79.41  ? 120 PHE R CA  1 
ATOM   645  C  C   . PHE A 1 241 ? 131.203 150.318 103.958 1.00 82.04  ? 120 PHE R C   1 
ATOM   646  O  O   . PHE A 1 241 ? 131.304 149.598 104.964 1.00 82.89  ? 120 PHE R O   1 
ATOM   647  C  CB  . PHE A 1 241 ? 129.221 151.840 103.761 1.00 80.54  ? 120 PHE R CB  1 
ATOM   648  C  CG  . PHE A 1 241 ? 128.605 153.171 104.067 1.00 81.50  ? 120 PHE R CG  1 
ATOM   649  C  CD1 . PHE A 1 241 ? 128.592 153.655 105.360 1.00 81.50  ? 120 PHE R CD1 1 
ATOM   650  C  CD2 . PHE A 1 241 ? 128.001 153.917 103.072 1.00 82.90  ? 120 PHE R CD2 1 
ATOM   651  C  CE1 . PHE A 1 241 ? 128.017 154.873 105.652 1.00 82.57  ? 120 PHE R CE1 1 
ATOM   652  C  CE2 . PHE A 1 241 ? 127.424 155.136 103.357 1.00 82.78  ? 120 PHE R CE2 1 
ATOM   653  C  CZ  . PHE A 1 241 ? 127.431 155.614 104.649 1.00 82.86  ? 120 PHE R CZ  1 
ATOM   654  N  N   . ASP A 1 242 ? 131.513 149.876 102.737 1.00 77.24  ? 121 ASP R N   1 
ATOM   655  C  CA  . ASP A 1 242 ? 131.878 148.478 102.544 1.00 72.48  ? 121 ASP R CA  1 
ATOM   656  C  C   . ASP A 1 242 ? 133.213 148.143 103.194 1.00 74.32  ? 121 ASP R C   1 
ATOM   657  O  O   . ASP A 1 242 ? 133.389 147.027 103.701 1.00 76.44  ? 121 ASP R O   1 
ATOM   658  C  CB  . ASP A 1 242 ? 131.897 148.145 101.055 1.00 70.11  ? 121 ASP R CB  1 
ATOM   659  C  CG  . ASP A 1 242 ? 130.507 148.069 100.463 1.00 73.66  ? 121 ASP R CG  1 
ATOM   660  O  OD1 . ASP A 1 242 ? 129.531 148.144 101.233 1.00 74.35  ? 121 ASP R OD1 1 
ATOM   661  O  OD2 . ASP A 1 242 ? 130.385 147.931 99.231  1.00 74.50  ? 121 ASP R OD2 1 
ATOM   662  N  N   . SER A 1 243 ? 134.160 149.084 103.209 1.00 71.39  ? 122 SER R N   1 
ATOM   663  C  CA  . SER A 1 243 ? 135.419 148.824 103.897 1.00 70.27  ? 122 SER R CA  1 
ATOM   664  C  C   . SER A 1 243 ? 135.196 148.621 105.391 1.00 70.57  ? 122 SER R C   1 
ATOM   665  O  O   . SER A 1 243 ? 135.802 147.732 106.003 1.00 70.54  ? 122 SER R O   1 
ATOM   666  C  CB  . SER A 1 243 ? 136.401 149.966 103.645 1.00 70.58  ? 122 SER R CB  1 
ATOM   667  O  OG  . SER A 1 243 ? 136.124 151.066 104.487 1.00 73.28  ? 122 SER R OG  1 
ATOM   668  N  N   . MET A 1 244 ? 134.326 149.432 105.994 1.00 64.70  ? 123 MET R N   1 
ATOM   669  C  CA  . MET A 1 244 ? 134.027 149.267 107.412 1.00 64.20  ? 123 MET R CA  1 
ATOM   670  C  C   . MET A 1 244 ? 133.384 147.917 107.683 1.00 65.59  ? 123 MET R C   1 
ATOM   671  O  O   . MET A 1 244 ? 133.744 147.232 108.652 1.00 68.56  ? 123 MET R O   1 
ATOM   672  C  CB  . MET A 1 244 ? 133.123 150.398 107.895 1.00 65.88  ? 123 MET R CB  1 
ATOM   673  C  CG  . MET A 1 244 ? 133.804 151.751 107.948 1.00 67.97  ? 123 MET R CG  1 
ATOM   674  S  SD  . MET A 1 244 ? 132.639 153.123 107.955 1.00 76.16  ? 123 MET R SD  1 
ATOM   675  C  CE  . MET A 1 244 ? 131.241 152.391 108.796 1.00 66.83  ? 123 MET R CE  1 
ATOM   676  N  N   . ILE A 1 245 ? 132.442 147.506 106.828 1.00 64.41  ? 124 ILE R N   1 
ATOM   677  C  CA  . ILE A 1 245 ? 131.810 146.199 107.013 1.00 62.48  ? 124 ILE R CA  1 
ATOM   678  C  C   . ILE A 1 245 ? 132.846 145.083 106.937 1.00 62.41  ? 124 ILE R C   1 
ATOM   679  O  O   . ILE A 1 245 ? 132.841 144.158 107.758 1.00 64.05  ? 124 ILE R O   1 
ATOM   680  C  CB  . ILE A 1 245 ? 130.685 145.979 105.988 1.00 62.21  ? 124 ILE R CB  1 
ATOM   681  C  CG1 . ILE A 1 245 ? 129.686 147.129 106.019 1.00 63.13  ? 124 ILE R CG1 1 
ATOM   682  C  CG2 . ILE A 1 245 ? 129.970 144.686 106.286 1.00 62.20  ? 124 ILE R CG2 1 
ATOM   683  C  CD1 . ILE A 1 245 ? 128.648 147.050 104.933 1.00 60.31  ? 124 ILE R CD1 1 
ATOM   684  N  N   . CYS A 1 246 ? 133.753 145.151 105.958 1.00 58.26  ? 125 CYS R N   1 
ATOM   685  C  CA  . CYS A 1 246 ? 134.748 144.092 105.794 1.00 56.44  ? 125 CYS R CA  1 
ATOM   686  C  C   . CYS A 1 246 ? 135.688 144.012 106.993 1.00 55.93  ? 125 CYS R C   1 
ATOM   687  O  O   . CYS A 1 246 ? 135.972 142.916 107.505 1.00 58.14  ? 125 CYS R O   1 
ATOM   688  C  CB  . CYS A 1 246 ? 135.539 144.315 104.508 1.00 57.69  ? 125 CYS R CB  1 
ATOM   689  S  SG  . CYS A 1 246 ? 136.442 142.871 103.927 1.00 60.21  ? 125 CYS R SG  1 
ATOM   690  N  N   . ILE A 1 247 ? 136.200 145.159 107.448 1.00 56.15  ? 126 ILE R N   1 
ATOM   691  C  CA  . ILE A 1 247 ? 137.142 145.116 108.563 1.00 55.61  ? 126 ILE R CA  1 
ATOM   692  C  C   . ILE A 1 247 ? 136.448 144.612 109.821 1.00 50.90  ? 126 ILE R C   1 
ATOM   693  O  O   . ILE A 1 247 ? 137.029 143.843 110.595 1.00 52.90  ? 126 ILE R O   1 
ATOM   694  C  CB  . ILE A 1 247 ? 137.827 146.480 108.789 1.00 57.27  ? 126 ILE R CB  1 
ATOM   695  C  CG1 . ILE A 1 247 ? 136.903 147.490 109.461 1.00 57.14  ? 126 ILE R CG1 1 
ATOM   696  C  CG2 . ILE A 1 247 ? 138.373 147.045 107.492 1.00 55.73  ? 126 ILE R CG2 1 
ATOM   697  C  CD1 . ILE A 1 247 ? 137.647 148.640 110.083 1.00 58.28  ? 126 ILE R CD1 1 
ATOM   698  N  N   . SER A 1 248 ? 135.186 145.002 110.030 1.00 47.90  ? 127 SER R N   1 
ATOM   699  C  CA  . SER A 1 248 ? 134.468 144.524 111.204 1.00 46.41  ? 127 SER R CA  1 
ATOM   700  C  C   . SER A 1 248 ? 134.205 143.027 111.121 1.00 50.85  ? 127 SER R C   1 
ATOM   701  O  O   . SER A 1 248 ? 134.249 142.329 112.139 1.00 56.81  ? 127 SER R O   1 
ATOM   702  C  CB  . SER A 1 248 ? 133.167 145.297 111.358 1.00 51.19  ? 127 SER R CB  1 
ATOM   703  O  OG  . SER A 1 248 ? 132.407 145.229 110.169 1.00 52.97  ? 127 SER R OG  1 
ATOM   704  N  N   . LEU A 1 249 ? 133.948 142.513 109.916 1.00 46.81  ? 128 LEU R N   1 
ATOM   705  C  CA  . LEU A 1 249 ? 133.755 141.076 109.724 1.00 43.43  ? 128 LEU R CA  1 
ATOM   706  C  C   . LEU A 1 249 ? 134.998 140.291 110.135 1.00 41.40  ? 128 LEU R C   1 
ATOM   707  O  O   . LEU A 1 249 ? 134.933 139.354 110.950 1.00 44.53  ? 128 LEU R O   1 
ATOM   708  C  CB  . LEU A 1 249 ? 133.432 140.818 108.254 1.00 42.27  ? 128 LEU R CB  1 
ATOM   709  C  CG  . LEU A 1 249 ? 132.530 139.685 107.797 1.00 44.33  ? 128 LEU R CG  1 
ATOM   710  C  CD1 . LEU A 1 249 ? 131.097 140.070 108.046 1.00 46.67  ? 128 LEU R CD1 1 
ATOM   711  C  CD2 . LEU A 1 249 ? 132.761 139.416 106.328 1.00 39.34  ? 128 LEU R CD2 1 
ATOM   712  N  N   . VAL A 1 250 ? 136.148 140.674 109.580 1.00 38.25  ? 129 VAL R N   1 
ATOM   713  C  CA  . VAL A 1 250 ? 137.381 139.957 109.889 1.00 37.06  ? 129 VAL R CA  1 
ATOM   714  C  C   . VAL A 1 250 ? 137.724 140.093 111.369 1.00 37.06  ? 129 VAL R C   1 
ATOM   715  O  O   . VAL A 1 250 ? 138.187 139.135 112.001 1.00 38.14  ? 129 VAL R O   1 
ATOM   716  C  CB  . VAL A 1 250 ? 138.530 140.441 108.987 1.00 38.82  ? 129 VAL R CB  1 
ATOM   717  C  CG1 . VAL A 1 250 ? 139.750 139.574 109.190 1.00 40.24  ? 129 VAL R CG1 1 
ATOM   718  C  CG2 . VAL A 1 250 ? 138.110 140.408 107.533 1.00 35.58  ? 129 VAL R CG2 1 
ATOM   719  N  N   . ALA A 1 251 ? 137.500 141.277 111.949 1.00 38.29  ? 130 ALA R N   1 
ATOM   720  C  CA  . ALA A 1 251 ? 137.790 141.469 113.366 1.00 33.10  ? 130 ALA R CA  1 
ATOM   721  C  C   . ALA A 1 251 ? 136.900 140.598 114.243 1.00 36.36  ? 130 ALA R C   1 
ATOM   722  O  O   . ALA A 1 251 ? 137.357 140.057 115.257 1.00 43.48  ? 130 ALA R O   1 
ATOM   723  C  CB  . ALA A 1 251 ? 137.635 142.940 113.739 1.00 30.95  ? 130 ALA R CB  1 
ATOM   724  N  N   . SER A 1 252 ? 135.626 140.454 113.875 1.00 28.49  ? 131 SER R N   1 
ATOM   725  C  CA  . SER A 1 252 ? 134.723 139.595 114.632 1.00 27.12  ? 131 SER R CA  1 
ATOM   726  C  C   . SER A 1 252 ? 135.216 138.154 114.638 1.00 34.76  ? 131 SER R C   1 
ATOM   727  O  O   . SER A 1 252 ? 135.281 137.506 115.695 1.00 38.56  ? 131 SER R O   1 
ATOM   728  C  CB  . SER A 1 252 ? 133.319 139.682 114.041 1.00 27.65  ? 131 SER R CB  1 
ATOM   729  O  OG  . SER A 1 252 ? 132.337 139.314 114.986 1.00 40.20  ? 131 SER R OG  1 
ATOM   730  N  N   . ILE A 1 253 ? 135.594 137.640 113.464 1.00 33.46  ? 132 ILE R N   1 
ATOM   731  C  CA  . ILE A 1 253 ? 136.062 136.254 113.397 1.00 26.48  ? 132 ILE R CA  1 
ATOM   732  C  C   . ILE A 1 253 ? 137.354 136.080 114.194 1.00 30.86  ? 132 ILE R C   1 
ATOM   733  O  O   . ILE A 1 253 ? 137.534 135.084 114.915 1.00 38.14  ? 132 ILE R O   1 
ATOM   734  C  CB  . ILE A 1 253 ? 136.232 135.814 111.933 1.00 23.49  ? 132 ILE R CB  1 
ATOM   735  C  CG1 . ILE A 1 253 ? 134.897 135.862 111.202 1.00 27.55  ? 132 ILE R CG1 1 
ATOM   736  C  CG2 . ILE A 1 253 ? 136.757 134.410 111.862 1.00 24.88  ? 132 ILE R CG2 1 
ATOM   737  C  CD1 . ILE A 1 253 ? 134.951 135.266 109.822 1.00 30.04  ? 132 ILE R CD1 1 
ATOM   738  N  N   . CYS A 1 254 ? 138.268 137.047 114.089 1.00 28.10  ? 133 CYS R N   1 
ATOM   739  C  CA  . CYS A 1 254 ? 139.545 136.947 114.792 1.00 23.41  ? 133 CYS R CA  1 
ATOM   740  C  C   . CYS A 1 254 ? 139.356 136.959 116.304 1.00 23.84  ? 133 CYS R C   1 
ATOM   741  O  O   . CYS A 1 254 ? 140.052 136.239 117.028 1.00 22.87  ? 133 CYS R O   1 
ATOM   742  C  CB  . CYS A 1 254 ? 140.467 138.087 114.366 1.00 31.22  ? 133 CYS R CB  1 
ATOM   743  S  SG  . CYS A 1 254 ? 141.260 137.870 112.768 1.00 39.65  ? 133 CYS R SG  1 
ATOM   744  N  N   . ASN A 1 255 ? 138.432 137.781 116.804 1.00 22.25  ? 134 ASN R N   1 
ATOM   745  C  CA  . ASN A 1 255 ? 138.189 137.820 118.242 1.00 19.93  ? 134 ASN R CA  1 
ATOM   746  C  C   . ASN A 1 255 ? 137.526 136.540 118.730 1.00 24.04  ? 134 ASN R C   1 
ATOM   747  O  O   . ASN A 1 255 ? 137.814 136.067 119.841 1.00 30.68  ? 134 ASN R O   1 
ATOM   748  C  CB  . ASN A 1 255 ? 137.344 139.038 118.595 1.00 26.53  ? 134 ASN R CB  1 
ATOM   749  C  CG  . ASN A 1 255 ? 138.096 140.334 118.413 1.00 33.52  ? 134 ASN R CG  1 
ATOM   750  O  OD1 . ASN A 1 255 ? 138.964 140.676 119.212 1.00 32.46  ? 134 ASN R OD1 1 
ATOM   751  N  ND2 . ASN A 1 255 ? 137.775 141.060 117.354 1.00 33.32  ? 134 ASN R ND2 1 
ATOM   752  N  N   . LEU A 1 256 ? 136.647 135.954 117.911 1.00 22.06  ? 135 LEU R N   1 
ATOM   753  C  CA  . LEU A 1 256 ? 136.072 134.658 118.265 1.00 19.64  ? 135 LEU R CA  1 
ATOM   754  C  C   . LEU A 1 256 ? 137.152 133.590 118.401 1.00 15.55  ? 135 LEU R C   1 
ATOM   755  O  O   . LEU A 1 256 ? 137.093 132.753 119.306 1.00 11.90  ? 135 LEU R O   1 
ATOM   756  C  CB  . LEU A 1 256 ? 135.037 134.234 117.226 1.00 22.69  ? 135 LEU R CB  1 
ATOM   757  C  CG  . LEU A 1 256 ? 133.643 134.838 117.357 1.00 23.66  ? 135 LEU R CG  1 
ATOM   758  C  CD1 . LEU A 1 256 ? 132.835 134.557 116.114 1.00 25.12  ? 135 LEU R CD1 1 
ATOM   759  C  CD2 . LEU A 1 256 ? 132.945 134.300 118.579 1.00 24.42  ? 135 LEU R CD2 1 
ATOM   760  N  N   . LEU A 1 257 ? 138.138 133.592 117.505 1.00 13.00  ? 136 LEU R N   1 
ATOM   761  C  CA  . LEU A 1 257 ? 139.217 132.610 117.620 1.00 10.11  ? 136 LEU R CA  1 
ATOM   762  C  C   . LEU A 1 257 ? 140.135 132.908 118.806 1.00 15.57  ? 136 LEU R C   1 
ATOM   763  O  O   . LEU A 1 257 ? 140.646 131.982 119.453 1.00 24.93  ? 136 LEU R O   1 
ATOM   764  C  CB  . LEU A 1 257 ? 140.016 132.555 116.322 1.00 11.58  ? 136 LEU R CB  1 
ATOM   765  C  CG  . LEU A 1 257 ? 141.300 131.731 116.334 1.00 18.34  ? 136 LEU R CG  1 
ATOM   766  C  CD1 . LEU A 1 257 ? 141.005 130.284 116.633 1.00 20.33  ? 136 LEU R CD1 1 
ATOM   767  C  CD2 . LEU A 1 257 ? 142.024 131.854 115.014 1.00 22.46  ? 136 LEU R CD2 1 
ATOM   768  N  N   . ALA A 1 258 ? 140.370 134.190 119.100 1.00 31.52  ? 137 ALA R N   1 
ATOM   769  C  CA  . ALA A 1 258 ? 141.247 134.556 120.211 1.00 16.51  ? 137 ALA R CA  1 
ATOM   770  C  C   . ALA A 1 258 ? 140.671 134.122 121.550 1.00 11.06  ? 137 ALA R C   1 
ATOM   771  O  O   . ALA A 1 258 ? 141.412 133.676 122.434 1.00 25.21  ? 137 ALA R O   1 
ATOM   772  C  CB  . ALA A 1 258 ? 141.502 136.059 120.206 1.00 17.04  ? 137 ALA R CB  1 
ATOM   773  N  N   . ILE A 1 259 ? 139.355 134.251 121.725 1.00 5.57   ? 138 ILE R N   1 
ATOM   774  C  CA  . ILE A 1 259 ? 138.726 133.769 122.955 1.00 10.58  ? 138 ILE R CA  1 
ATOM   775  C  C   . ILE A 1 259 ? 139.004 132.280 123.153 1.00 19.78  ? 138 ILE R C   1 
ATOM   776  O  O   . ILE A 1 259 ? 139.355 131.832 124.253 1.00 27.46  ? 138 ILE R O   1 
ATOM   777  C  CB  . ILE A 1 259 ? 137.216 134.058 122.933 1.00 18.22  ? 138 ILE R CB  1 
ATOM   778  C  CG1 . ILE A 1 259 ? 136.954 135.552 123.089 1.00 18.13  ? 138 ILE R CG1 1 
ATOM   779  C  CG2 . ILE A 1 259 ? 136.508 133.284 124.015 1.00 13.41  ? 138 ILE R CG2 1 
ATOM   780  C  CD1 . ILE A 1 259 ? 135.533 135.947 122.821 1.00 12.15  ? 138 ILE R CD1 1 
ATOM   781  N  N   . ALA A 1 260 ? 138.853 131.493 122.084 1.00 22.70  ? 139 ALA R N   1 
ATOM   782  C  CA  . ALA A 1 260 ? 139.055 130.050 122.173 1.00 9.54   ? 139 ALA R CA  1 
ATOM   783  C  C   . ALA A 1 260 ? 140.495 129.705 122.510 1.00 8.75   ? 139 ALA R C   1 
ATOM   784  O  O   . ALA A 1 260 ? 140.750 128.798 123.308 1.00 18.39  ? 139 ALA R O   1 
ATOM   785  C  CB  . ALA A 1 260 ? 138.646 129.383 120.863 1.00 12.90  ? 139 ALA R CB  1 
ATOM   786  N  N   . VAL A 1 261 ? 141.453 130.402 121.903 1.00 10.72  ? 140 VAL R N   1 
ATOM   787  C  CA  . VAL A 1 261 ? 142.854 130.129 122.220 1.00 7.51   ? 140 VAL R CA  1 
ATOM   788  C  C   . VAL A 1 261 ? 143.152 130.468 123.678 1.00 19.48  ? 140 VAL R C   1 
ATOM   789  O  O   . VAL A 1 261 ? 143.909 129.760 124.356 1.00 21.87  ? 140 VAL R O   1 
ATOM   790  C  CB  . VAL A 1 261 ? 143.786 130.884 121.259 1.00 0.00   ? 140 VAL R CB  1 
ATOM   791  C  CG1 . VAL A 1 261 ? 145.216 130.561 121.576 1.00 10.85  ? 140 VAL R CG1 1 
ATOM   792  C  CG2 . VAL A 1 261 ? 143.492 130.501 119.841 1.00 8.92   ? 140 VAL R CG2 1 
ATOM   793  N  N   . ASP A 1 262 ? 142.566 131.554 124.188 1.00 20.15  ? 141 ASP R N   1 
ATOM   794  C  CA  . ASP A 1 262 ? 142.773 131.903 125.591 1.00 10.68  ? 141 ASP R CA  1 
ATOM   795  C  C   . ASP A 1 262 ? 142.227 130.825 126.521 1.00 9.04   ? 141 ASP R C   1 
ATOM   796  O  O   . ASP A 1 262 ? 142.884 130.448 127.498 1.00 15.32  ? 141 ASP R O   1 
ATOM   797  C  CB  . ASP A 1 262 ? 142.126 133.252 125.892 1.00 18.67  ? 141 ASP R CB  1 
ATOM   798  C  CG  . ASP A 1 262 ? 142.429 133.745 127.286 1.00 31.19  ? 141 ASP R CG  1 
ATOM   799  O  OD1 . ASP A 1 262 ? 143.446 134.436 127.466 1.00 35.87  ? 141 ASP R OD1 1 
ATOM   800  O  OD2 . ASP A 1 262 ? 141.645 133.450 128.206 1.00 32.00  ? 141 ASP R OD2 1 
ATOM   801  N  N   . ARG A 1 263 ? 141.025 130.316 126.231 1.00 17.03  ? 142 ARG R N   1 
ATOM   802  C  CA  . ARG A 1 263 ? 140.463 129.236 127.043 1.00 10.50  ? 142 ARG R CA  1 
ATOM   803  C  C   . ARG A 1 263 ? 141.341 127.991 126.995 1.00 4.49   ? 142 ARG R C   1 
ATOM   804  O  O   . ARG A 1 263 ? 141.570 127.334 128.019 1.00 7.96   ? 142 ARG R O   1 
ATOM   805  C  CB  . ARG A 1 263 ? 139.056 128.896 126.567 1.00 6.70   ? 142 ARG R CB  1 
ATOM   806  C  CG  . ARG A 1 263 ? 138.066 130.017 126.650 1.00 0.36   ? 142 ARG R CG  1 
ATOM   807  C  CD  . ARG A 1 263 ? 136.688 129.492 126.381 1.00 7.94   ? 142 ARG R CD  1 
ATOM   808  N  NE  . ARG A 1 263 ? 135.655 130.459 126.716 1.00 16.75  ? 142 ARG R NE  1 
ATOM   809  C  CZ  . ARG A 1 263 ? 134.355 130.209 126.671 1.00 24.34  ? 142 ARG R CZ  1 
ATOM   810  N  NH1 . ARG A 1 263 ? 133.892 129.029 126.305 1.00 22.03  ? 142 ARG R NH1 1 
ATOM   811  N  NH2 . ARG A 1 263 ? 133.498 131.167 127.004 1.00 23.17  ? 142 ARG R NH2 1 
ATOM   812  N  N   . TYR A 1 264 ? 141.832 127.650 125.806 1.00 14.24  ? 143 TYR R N   1 
ATOM   813  C  CA  . TYR A 1 264 ? 142.709 126.497 125.660 1.00 9.24   ? 143 TYR R CA  1 
ATOM   814  C  C   . TYR A 1 264 ? 143.949 126.644 126.522 1.00 8.19   ? 143 TYR R C   1 
ATOM   815  O  O   . TYR A 1 264 ? 144.371 125.692 127.182 1.00 10.65  ? 143 TYR R O   1 
ATOM   816  C  CB  . TYR A 1 264 ? 143.089 126.331 124.189 1.00 5.90   ? 143 TYR R CB  1 
ATOM   817  C  CG  . TYR A 1 264 ? 143.769 125.033 123.854 1.00 11.02  ? 143 TYR R CG  1 
ATOM   818  C  CD1 . TYR A 1 264 ? 143.033 123.898 123.560 1.00 9.42   ? 143 TYR R CD1 1 
ATOM   819  C  CD2 . TYR A 1 264 ? 145.148 124.943 123.819 1.00 13.06  ? 143 TYR R CD2 1 
ATOM   820  C  CE1 . TYR A 1 264 ? 143.650 122.716 123.250 1.00 7.62   ? 143 TYR R CE1 1 
ATOM   821  C  CE2 . TYR A 1 264 ? 145.771 123.763 123.510 1.00 13.34  ? 143 TYR R CE2 1 
ATOM   822  C  CZ  . TYR A 1 264 ? 145.016 122.655 123.230 1.00 14.71  ? 143 TYR R CZ  1 
ATOM   823  O  OH  . TYR A 1 264 ? 145.639 121.475 122.923 1.00 21.98  ? 143 TYR R OH  1 
ATOM   824  N  N   . VAL A 1 265 ? 144.545 127.835 126.530 1.00 18.44  ? 144 VAL R N   1 
ATOM   825  C  CA  . VAL A 1 265 ? 145.776 128.043 127.285 1.00 14.85  ? 144 VAL R CA  1 
ATOM   826  C  C   . VAL A 1 265 ? 145.510 127.994 128.786 1.00 8.60   ? 144 VAL R C   1 
ATOM   827  O  O   . VAL A 1 265 ? 146.322 127.467 129.551 1.00 8.06   ? 144 VAL R O   1 
ATOM   828  C  CB  . VAL A 1 265 ? 146.441 129.360 126.852 1.00 19.55  ? 144 VAL R CB  1 
ATOM   829  C  CG1 . VAL A 1 265 ? 147.499 129.781 127.843 1.00 20.89  ? 144 VAL R CG1 1 
ATOM   830  C  CG2 . VAL A 1 265 ? 147.050 129.199 125.477 1.00 9.47   ? 144 VAL R CG2 1 
ATOM   831  N  N   . THR A 1 266 ? 144.373 128.532 129.238 1.00 13.89  ? 145 THR R N   1 
ATOM   832  C  CA  . THR A 1 266 ? 144.054 128.430 130.661 1.00 5.58   ? 145 THR R CA  1 
ATOM   833  C  C   . THR A 1 266 ? 143.889 126.981 131.091 1.00 10.58  ? 145 THR R C   1 
ATOM   834  O  O   . THR A 1 266 ? 144.371 126.590 132.157 1.00 17.26  ? 145 THR R O   1 
ATOM   835  C  CB  . THR A 1 266 ? 142.789 129.210 131.012 1.00 7.06   ? 145 THR R CB  1 
ATOM   836  O  OG1 . THR A 1 266 ? 141.655 128.621 130.372 1.00 10.20  ? 145 THR R OG1 1 
ATOM   837  C  CG2 . THR A 1 266 ? 142.911 130.648 130.612 1.00 16.17  ? 145 THR R CG2 1 
ATOM   838  N  N   . ILE A 1 267 ? 143.201 126.166 130.288 1.00 23.00  ? 146 ILE R N   1 
ATOM   839  C  CA  . ILE A 1 267 ? 142.941 124.790 130.716 1.00 12.32  ? 146 ILE R CA  1 
ATOM   840  C  C   . ILE A 1 267 ? 144.193 123.929 130.611 1.00 9.19   ? 146 ILE R C   1 
ATOM   841  O  O   . ILE A 1 267 ? 144.500 123.153 131.519 1.00 18.04  ? 146 ILE R O   1 
ATOM   842  C  CB  . ILE A 1 267 ? 141.781 124.175 129.919 1.00 8.99   ? 146 ILE R CB  1 
ATOM   843  C  CG1 . ILE A 1 267 ? 140.459 124.799 130.338 1.00 15.89  ? 146 ILE R CG1 1 
ATOM   844  C  CG2 . ILE A 1 267 ? 141.733 122.690 130.136 1.00 5.04   ? 146 ILE R CG2 1 
ATOM   845  C  CD1 . ILE A 1 267 ? 139.416 124.698 129.284 1.00 14.86  ? 146 ILE R CD1 1 
ATOM   846  N  N   . PHE A 1 268 ? 144.929 124.031 129.513 1.00 10.01  ? 147 PHE R N   1 
ATOM   847  C  CA  . PHE A 1 268 ? 145.977 123.058 129.243 1.00 12.06  ? 147 PHE R CA  1 
ATOM   848  C  C   . PHE A 1 268 ? 147.354 123.474 129.735 1.00 12.39  ? 147 PHE R C   1 
ATOM   849  O  O   . PHE A 1 268 ? 148.301 122.700 129.582 1.00 14.48  ? 147 PHE R O   1 
ATOM   850  C  CB  . PHE A 1 268 ? 146.022 122.742 127.748 1.00 12.99  ? 147 PHE R CB  1 
ATOM   851  C  CG  . PHE A 1 268 ? 145.030 121.694 127.341 1.00 18.12  ? 147 PHE R CG  1 
ATOM   852  C  CD1 . PHE A 1 268 ? 145.369 120.361 127.360 1.00 14.55  ? 147 PHE R CD1 1 
ATOM   853  C  CD2 . PHE A 1 268 ? 143.745 122.043 126.981 1.00 9.52   ? 147 PHE R CD2 1 
ATOM   854  C  CE1 . PHE A 1 268 ? 144.461 119.412 127.009 1.00 8.94   ? 147 PHE R CE1 1 
ATOM   855  C  CE2 . PHE A 1 268 ? 142.837 121.094 126.635 1.00 8.11   ? 147 PHE R CE2 1 
ATOM   856  C  CZ  . PHE A 1 268 ? 143.194 119.779 126.649 1.00 12.42  ? 147 PHE R CZ  1 
ATOM   857  N  N   . TYR A 1 269 ? 147.543 124.721 130.165 1.00 16.03  ? 148 TYR R N   1 
ATOM   858  C  CA  . TYR A 1 269 ? 148.805 125.208 130.744 1.00 15.10  ? 148 TYR R CA  1 
ATOM   859  C  C   . TYR A 1 269 ? 148.341 125.967 131.923 1.00 22.32  ? 148 TYR R C   1 
ATOM   860  O  O   . TYR A 1 269 ? 148.529 127.160 131.967 1.00 26.10  ? 148 TYR R O   1 
ATOM   861  C  CB  . TYR A 1 269 ? 149.539 126.153 129.828 1.00 6.56   ? 148 TYR R CB  1 
ATOM   862  C  CG  . TYR A 1 269 ? 149.953 125.562 128.509 1.00 19.08  ? 148 TYR R CG  1 
ATOM   863  C  CD1 . TYR A 1 269 ? 149.114 125.623 127.409 1.00 20.45  ? 148 TYR R CD1 1 
ATOM   864  C  CD2 . TYR A 1 269 ? 151.186 124.950 128.359 1.00 22.76  ? 148 TYR R CD2 1 
ATOM   865  C  CE1 . TYR A 1 269 ? 149.486 125.079 126.199 1.00 16.96  ? 148 TYR R CE1 1 
ATOM   866  C  CE2 . TYR A 1 269 ? 151.568 124.405 127.153 1.00 20.54  ? 148 TYR R CE2 1 
ATOM   867  C  CZ  . TYR A 1 269 ? 150.712 124.473 126.079 1.00 21.24  ? 148 TYR R CZ  1 
ATOM   868  O  OH  . TYR A 1 269 ? 151.086 123.932 124.876 1.00 25.61  ? 148 TYR R OH  1 
ATOM   869  N  N   . ALA A 1 270 ? 147.755 125.298 132.906 1.00 17.31  ? 149 ALA R N   1 
ATOM   870  C  CA  . ALA A 1 270 ? 147.105 125.967 134.023 1.00 19.55  ? 149 ALA R CA  1 
ATOM   871  C  C   . ALA A 1 270 ? 147.979 126.598 135.096 1.00 29.17  ? 149 ALA R C   1 
ATOM   872  O  O   . ALA A 1 270 ? 147.622 127.627 135.656 1.00 31.70  ? 149 ALA R O   1 
ATOM   873  C  CB  . ALA A 1 270 ? 146.159 124.966 134.651 1.00 3.28   ? 149 ALA R CB  1 
ATOM   874  N  N   . LEU A 1 271 ? 149.111 125.995 135.399 1.00 24.94  ? 150 LEU R N   1 
ATOM   875  C  CA  . LEU A 1 271 ? 149.958 126.498 136.445 1.00 8.28   ? 150 LEU R CA  1 
ATOM   876  C  C   . LEU A 1 271 ? 150.910 127.534 135.904 1.00 20.30  ? 150 LEU R C   1 
ATOM   877  O  O   . LEU A 1 271 ? 151.327 128.421 136.635 1.00 32.77  ? 150 LEU R O   1 
ATOM   878  C  CB  . LEU A 1 271 ? 150.713 125.328 137.061 1.00 14.08  ? 150 LEU R CB  1 
ATOM   879  C  CG  . LEU A 1 271 ? 149.954 124.254 137.844 1.00 11.62  ? 150 LEU R CG  1 
ATOM   880  C  CD1 . LEU A 1 271 ? 150.909 123.191 138.352 1.00 11.66  ? 150 LEU R CD1 1 
ATOM   881  C  CD2 . LEU A 1 271 ? 149.191 124.857 139.005 1.00 10.64  ? 150 LEU R CD2 1 
ATOM   882  N  N   . ARG A 1 272 ? 151.239 127.456 134.621 1.00 23.26  ? 151 ARG R N   1 
ATOM   883  C  CA  . ARG A 1 272 ? 152.156 128.407 133.997 1.00 13.83  ? 151 ARG R CA  1 
ATOM   884  C  C   . ARG A 1 272 ? 151.466 129.530 133.249 1.00 18.50  ? 151 ARG R C   1 
ATOM   885  O  O   . ARG A 1 272 ? 152.138 130.333 132.647 1.00 31.06  ? 151 ARG R O   1 
ATOM   886  C  CB  . ARG A 1 272 ? 153.101 127.674 133.065 1.00 19.18  ? 151 ARG R CB  1 
ATOM   887  C  CG  . ARG A 1 272 ? 154.122 126.803 133.768 1.00 25.47  ? 151 ARG R CG  1 
ATOM   888  C  CD  . ARG A 1 272 ? 155.441 127.535 133.935 1.00 28.80  ? 151 ARG R CD  1 
ATOM   889  N  NE  . ARG A 1 272 ? 155.812 128.268 132.730 1.00 36.14  ? 151 ARG R NE  1 
ATOM   890  C  CZ  . ARG A 1 272 ? 156.536 129.382 132.725 1.00 36.37  ? 151 ARG R CZ  1 
ATOM   891  N  NH1 . ARG A 1 272 ? 156.972 129.896 133.865 1.00 30.83  ? 151 ARG R NH1 1 
ATOM   892  N  NH2 . ARG A 1 272 ? 156.823 129.982 131.579 1.00 29.83  ? 151 ARG R NH2 1 
ATOM   893  N  N   . TYR A 1 273 ? 150.144 129.605 133.261 1.00 21.10  ? 152 TYR R N   1 
ATOM   894  C  CA  . TYR A 1 273 ? 149.422 130.716 132.660 1.00 12.56  ? 152 TYR R CA  1 
ATOM   895  C  C   . TYR A 1 273 ? 149.794 131.858 133.556 1.00 33.53  ? 152 TYR R C   1 
ATOM   896  O  O   . TYR A 1 273 ? 150.580 131.657 134.473 1.00 40.22  ? 152 TYR R O   1 
ATOM   897  C  CB  . TYR A 1 273 ? 147.946 130.437 132.720 1.00 16.27  ? 152 TYR R CB  1 
ATOM   898  C  CG  . TYR A 1 273 ? 147.032 131.433 132.061 1.00 25.37  ? 152 TYR R CG  1 
ATOM   899  C  CD1 . TYR A 1 273 ? 147.002 131.580 130.684 1.00 32.47  ? 152 TYR R CD1 1 
ATOM   900  C  CD2 . TYR A 1 273 ? 146.159 132.193 132.816 1.00 19.80  ? 152 TYR R CD2 1 
ATOM   901  C  CE1 . TYR A 1 273 ? 146.145 132.479 130.082 1.00 27.58  ? 152 TYR R CE1 1 
ATOM   902  C  CE2 . TYR A 1 273 ? 145.303 133.094 132.226 1.00 18.43  ? 152 TYR R CE2 1 
ATOM   903  C  CZ  . TYR A 1 273 ? 145.300 133.234 130.860 1.00 25.82  ? 152 TYR R CZ  1 
ATOM   904  O  OH  . TYR A 1 273 ? 144.441 134.133 130.278 1.00 25.53  ? 152 TYR R OH  1 
ATOM   905  N  N   . HIS A 1 274 ? 149.273 133.059 133.370 1.00 24.01  ? 153 HIS R N   1 
ATOM   906  C  CA  . HIS A 1 274 ? 149.580 134.139 134.314 1.00 18.40  ? 153 HIS R CA  1 
ATOM   907  C  C   . HIS A 1 274 ? 151.050 134.429 134.305 1.00 22.66  ? 153 HIS R C   1 
ATOM   908  O  O   . HIS A 1 274 ? 151.472 135.414 134.879 1.00 30.20  ? 153 HIS R O   1 
ATOM   909  C  CB  . HIS A 1 274 ? 149.143 133.782 135.723 1.00 15.68  ? 153 HIS R CB  1 
ATOM   910  C  CG  . HIS A 1 274 ? 147.732 134.159 136.036 1.00 20.51  ? 153 HIS R CG  1 
ATOM   911  N  ND1 . HIS A 1 274 ? 146.904 133.363 136.795 1.00 15.39  ? 153 HIS R ND1 1 
ATOM   912  C  CD2 . HIS A 1 274 ? 147.004 135.248 135.700 1.00 29.13  ? 153 HIS R CD2 1 
ATOM   913  C  CE1 . HIS A 1 274 ? 145.724 133.943 136.909 1.00 19.84  ? 153 HIS R CE1 1 
ATOM   914  N  NE2 . HIS A 1 274 ? 145.759 135.088 136.253 1.00 25.05  ? 153 HIS R NE2 1 
ATOM   915  N  N   . SER A 1 275 ? 151.839 133.586 133.660 1.00 20.10  ? 154 SER R N   1 
ATOM   916  C  CA  . SER A 1 275 ? 153.261 133.794 133.532 1.00 17.86  ? 154 SER R CA  1 
ATOM   917  C  C   . SER A 1 275 ? 153.594 133.609 132.078 1.00 25.74  ? 154 SER R C   1 
ATOM   918  O  O   . SER A 1 275 ? 154.757 133.632 131.703 1.00 36.71  ? 154 SER R O   1 
ATOM   919  C  CB  . SER A 1 275 ? 154.028 132.792 134.365 1.00 18.77  ? 154 SER R CB  1 
ATOM   920  O  OG  . SER A 1 275 ? 153.298 132.428 135.518 1.00 28.18  ? 154 SER R OG  1 
ATOM   921  N  N   . ILE A 1 276 ? 152.580 133.393 131.252 1.00 30.04  ? 155 ILE R N   1 
ATOM   922  C  CA  . ILE A 1 276 ? 152.769 133.249 129.821 1.00 28.64  ? 155 ILE R CA  1 
ATOM   923  C  C   . ILE A 1 276 ? 151.776 134.162 129.144 1.00 31.78  ? 155 ILE R C   1 
ATOM   924  O  O   . ILE A 1 276 ? 152.011 134.601 128.030 1.00 38.75  ? 155 ILE R O   1 
ATOM   925  C  CB  . ILE A 1 276 ? 152.563 131.809 129.314 1.00 26.41  ? 155 ILE R CB  1 
ATOM   926  C  CG1 . ILE A 1 276 ? 151.132 131.339 129.569 1.00 29.46  ? 155 ILE R CG1 1 
ATOM   927  C  CG2 . ILE A 1 276 ? 153.561 130.864 129.963 1.00 30.39  ? 155 ILE R CG2 1 
ATOM   928  C  CD1 . ILE A 1 276 ? 150.890 129.895 129.187 1.00 29.61  ? 155 ILE R CD1 1 
ATOM   929  N  N   . MET A 1 277 ? 150.668 134.465 129.805 1.00 36.82  ? 156 MET R N   1 
ATOM   930  C  CA  . MET A 1 277 ? 149.720 135.410 129.244 1.00 38.15  ? 156 MET R CA  1 
ATOM   931  C  C   . MET A 1 277 ? 149.394 136.518 130.221 1.00 42.24  ? 156 MET R C   1 
ATOM   932  O  O   . MET A 1 277 ? 148.569 136.339 131.111 1.00 44.51  ? 156 MET R O   1 
ATOM   933  C  CB  . MET A 1 277 ? 148.432 134.724 128.852 1.00 35.62  ? 156 MET R CB  1 
ATOM   934  C  CG  . MET A 1 277 ? 147.296 135.683 128.534 1.00 40.53  ? 156 MET R CG  1 
ATOM   935  S  SD  . MET A 1 277 ? 147.212 136.126 126.790 1.00 61.66  ? 156 MET R SD  1 
ATOM   936  C  CE  . MET A 1 277 ? 146.389 134.683 126.120 1.00 41.38  ? 156 MET R CE  1 
ATOM   937  N  N   . THR A 1 278 ? 150.019 137.678 130.044 1.00 50.16  ? 157 THR R N   1 
ATOM   938  C  CA  . THR A 1 278 ? 149.764 138.802 130.930 1.00 49.77  ? 157 THR R CA  1 
ATOM   939  C  C   . THR A 1 278 ? 148.837 139.802 130.242 1.00 51.33  ? 157 THR R C   1 
ATOM   940  O  O   . THR A 1 278 ? 148.445 139.628 129.086 1.00 57.20  ? 157 THR R O   1 
ATOM   941  C  CB  . THR A 1 278 ? 151.082 139.456 131.337 1.00 52.36  ? 157 THR R CB  1 
ATOM   942  O  OG1 . THR A 1 278 ? 151.871 139.695 130.167 1.00 56.25  ? 157 THR R OG1 1 
ATOM   943  C  CG2 . THR A 1 278 ? 151.858 138.538 132.253 1.00 48.27  ? 157 THR R CG2 1 
ATOM   944  N  N   . VAL A 1 279 ? 148.481 140.863 130.970 1.00 55.72  ? 158 VAL R N   1 
ATOM   945  C  CA  . VAL A 1 279 ? 147.605 141.890 130.408 1.00 61.62  ? 158 VAL R CA  1 
ATOM   946  C  C   . VAL A 1 279 ? 148.307 142.639 129.280 1.00 60.11  ? 158 VAL R C   1 
ATOM   947  O  O   . VAL A 1 279 ? 147.680 143.023 128.283 1.00 58.57  ? 158 VAL R O   1 
ATOM   948  C  CB  . VAL A 1 279 ? 147.123 142.844 131.517 1.00 63.23  ? 158 VAL R CB  1 
ATOM   949  C  CG1 . VAL A 1 279 ? 146.819 144.219 130.956 1.00 58.15  ? 158 VAL R CG1 1 
ATOM   950  C  CG2 . VAL A 1 279 ? 145.896 142.274 132.206 1.00 62.71  ? 158 VAL R CG2 1 
ATOM   951  N  N   . ARG A 1 280 ? 149.618 142.847 129.410 1.00 56.14  ? 159 ARG R N   1 
ATOM   952  C  CA  . ARG A 1 280 ? 150.366 143.512 128.350 1.00 55.65  ? 159 ARG R CA  1 
ATOM   953  C  C   . ARG A 1 280 ? 150.292 142.726 127.051 1.00 58.23  ? 159 ARG R C   1 
ATOM   954  O  O   . ARG A 1 280 ? 150.101 143.306 125.976 1.00 61.32  ? 159 ARG R O   1 
ATOM   955  C  CB  . ARG A 1 280 ? 151.816 143.703 128.780 1.00 57.91  ? 159 ARG R CB  1 
ATOM   956  C  CG  . ARG A 1 280 ? 152.532 144.833 128.068 1.00 59.18  ? 159 ARG R CG  1 
ATOM   957  C  CD  . ARG A 1 280 ? 153.646 145.397 128.934 1.00 58.67  ? 159 ARG R CD  1 
ATOM   958  N  NE  . ARG A 1 280 ? 154.460 146.374 128.221 1.00 62.63  ? 159 ARG R NE  1 
ATOM   959  C  CZ  . ARG A 1 280 ? 154.089 147.623 127.977 1.00 64.11  ? 159 ARG R CZ  1 
ATOM   960  N  NH1 . ARG A 1 280 ? 152.904 148.078 128.350 1.00 63.00  ? 159 ARG R NH1 1 
ATOM   961  N  NH2 . ARG A 1 280 ? 154.927 148.435 127.338 1.00 60.93  ? 159 ARG R NH2 1 
ATOM   962  N  N   . LYS A 1 281 ? 150.422 141.401 127.131 1.00 53.36  ? 160 LYS R N   1 
ATOM   963  C  CA  . LYS A 1 281 ? 150.340 140.579 125.930 1.00 51.07  ? 160 LYS R CA  1 
ATOM   964  C  C   . LYS A 1 281 ? 148.921 140.520 125.376 1.00 49.27  ? 160 LYS R C   1 
ATOM   965  O  O   . LYS A 1 281 ? 148.739 140.499 124.154 1.00 50.85  ? 160 LYS R O   1 
ATOM   966  C  CB  . LYS A 1 281 ? 150.880 139.183 126.220 1.00 51.07  ? 160 LYS R CB  1 
ATOM   967  C  CG  . LYS A 1 281 ? 152.394 139.139 126.250 1.00 53.25  ? 160 LYS R CG  1 
ATOM   968  C  CD  . LYS A 1 281 ? 152.916 138.112 127.231 1.00 54.19  ? 160 LYS R CD  1 
ATOM   969  C  CE  . LYS A 1 281 ? 153.616 136.974 126.511 1.00 52.17  ? 160 LYS R CE  1 
ATOM   970  N  NZ  . LYS A 1 281 ? 154.582 136.272 127.395 1.00 52.10  ? 160 LYS R NZ  1 
ATOM   971  N  N   . ALA A 1 282 ? 147.907 140.526 126.242 1.00 48.02  ? 161 ALA R N   1 
ATOM   972  C  CA  . ALA A 1 282 ? 146.533 140.593 125.756 1.00 48.92  ? 161 ALA R CA  1 
ATOM   973  C  C   . ALA A 1 282 ? 146.291 141.870 124.964 1.00 54.68  ? 161 ALA R C   1 
ATOM   974  O  O   . ALA A 1 282 ? 145.701 141.834 123.876 1.00 60.07  ? 161 ALA R O   1 
ATOM   975  C  CB  . ALA A 1 282 ? 145.552 140.498 126.920 1.00 48.67  ? 161 ALA R CB  1 
ATOM   976  N  N   . LEU A 1 283 ? 146.753 143.010 125.482 1.00 56.92  ? 162 LEU R N   1 
ATOM   977  C  CA  . LEU A 1 283 ? 146.542 144.268 124.771 1.00 51.08  ? 162 LEU R CA  1 
ATOM   978  C  C   . LEU A 1 283 ? 147.359 144.329 123.486 1.00 49.93  ? 162 LEU R C   1 
ATOM   979  O  O   . LEU A 1 283 ? 146.861 144.792 122.451 1.00 55.04  ? 162 LEU R O   1 
ATOM   980  C  CB  . LEU A 1 283 ? 146.870 145.446 125.682 1.00 51.85  ? 162 LEU R CB  1 
ATOM   981  C  CG  . LEU A 1 283 ? 145.935 145.620 126.879 1.00 55.10  ? 162 LEU R CG  1 
ATOM   982  C  CD1 . LEU A 1 283 ? 146.095 146.994 127.492 1.00 55.60  ? 162 LEU R CD1 1 
ATOM   983  C  CD2 . LEU A 1 283 ? 144.494 145.393 126.472 1.00 54.25  ? 162 LEU R CD2 1 
ATOM   984  N  N   . THR A 1 284 ? 148.612 143.864 123.524 1.00 46.81  ? 163 THR R N   1 
ATOM   985  C  CA  . THR A 1 284 ? 149.433 143.912 122.323 1.00 50.45  ? 163 THR R CA  1 
ATOM   986  C  C   . THR A 1 284 ? 148.981 142.909 121.273 1.00 53.63  ? 163 THR R C   1 
ATOM   987  O  O   . THR A 1 284 ? 149.381 143.029 120.111 1.00 51.94  ? 163 THR R O   1 
ATOM   988  C  CB  . THR A 1 284 ? 150.905 143.673 122.652 1.00 49.12  ? 163 THR R CB  1 
ATOM   989  O  OG1 . THR A 1 284 ? 151.703 144.050 121.526 1.00 53.57  ? 163 THR R OG1 1 
ATOM   990  C  CG2 . THR A 1 284 ? 151.160 142.218 122.923 1.00 48.61  ? 163 THR R CG2 1 
ATOM   991  N  N   . LEU A 1 285 ? 148.175 141.916 121.649 1.00 55.05  ? 164 LEU R N   1 
ATOM   992  C  CA  . LEU A 1 285 ? 147.584 141.039 120.648 1.00 49.39  ? 164 LEU R CA  1 
ATOM   993  C  C   . LEU A 1 285 ? 146.271 141.591 120.116 1.00 48.60  ? 164 LEU R C   1 
ATOM   994  O  O   . LEU A 1 285 ? 145.983 141.444 118.926 1.00 55.22  ? 164 LEU R O   1 
ATOM   995  C  CB  . LEU A 1 285 ? 147.376 139.639 121.224 1.00 48.15  ? 164 LEU R CB  1 
ATOM   996  C  CG  . LEU A 1 285 ? 148.639 138.774 121.220 1.00 53.66  ? 164 LEU R CG  1 
ATOM   997  C  CD1 . LEU A 1 285 ? 148.555 137.678 122.262 1.00 55.63  ? 164 LEU R CD1 1 
ATOM   998  C  CD2 . LEU A 1 285 ? 148.885 138.187 119.845 1.00 49.92  ? 164 LEU R CD2 1 
ATOM   999  N  N   . ILE A 1 286 ? 145.474 142.238 120.967 1.00 45.07  ? 165 ILE R N   1 
ATOM   1000 C  CA  . ILE A 1 286 ? 144.224 142.838 120.505 1.00 44.99  ? 165 ILE R CA  1 
ATOM   1001 C  C   . ILE A 1 286 ? 144.502 143.945 119.493 1.00 48.49  ? 165 ILE R C   1 
ATOM   1002 O  O   . ILE A 1 286 ? 143.848 144.034 118.442 1.00 46.80  ? 165 ILE R O   1 
ATOM   1003 C  CB  . ILE A 1 286 ? 143.411 143.363 121.698 1.00 44.15  ? 165 ILE R CB  1 
ATOM   1004 C  CG1 . ILE A 1 286 ? 142.812 142.201 122.482 1.00 44.84  ? 165 ILE R CG1 1 
ATOM   1005 C  CG2 . ILE A 1 286 ? 142.330 144.307 121.225 1.00 42.83  ? 165 ILE R CG2 1 
ATOM   1006 C  CD1 . ILE A 1 286 ? 142.051 142.629 123.693 1.00 45.67  ? 165 ILE R CD1 1 
ATOM   1007 N  N   . VAL A 1 287 ? 145.475 144.809 119.794 1.00 54.08  ? 166 VAL R N   1 
ATOM   1008 C  CA  . VAL A 1 287 ? 145.771 145.908 118.880 1.00 50.52  ? 166 VAL R CA  1 
ATOM   1009 C  C   . VAL A 1 287 ? 146.308 145.375 117.556 1.00 47.87  ? 166 VAL R C   1 
ATOM   1010 O  O   . VAL A 1 287 ? 145.987 145.904 116.486 1.00 52.71  ? 166 VAL R O   1 
ATOM   1011 C  CB  . VAL A 1 287 ? 146.735 146.919 119.533 1.00 49.48  ? 166 VAL R CB  1 
ATOM   1012 C  CG1 . VAL A 1 287 ? 148.066 146.279 119.862 1.00 51.91  ? 166 VAL R CG1 1 
ATOM   1013 C  CG2 . VAL A 1 287 ? 146.936 148.118 118.628 1.00 51.89  ? 166 VAL R CG2 1 
ATOM   1014 N  N   . ALA A 1 288 ? 147.116 144.315 117.599 1.00 43.14  ? 167 ALA R N   1 
ATOM   1015 C  CA  . ALA A 1 288 ? 147.606 143.709 116.366 1.00 47.07  ? 167 ALA R CA  1 
ATOM   1016 C  C   . ALA A 1 288 ? 146.468 143.093 115.561 1.00 48.41  ? 167 ALA R C   1 
ATOM   1017 O  O   . ALA A 1 288 ? 146.438 143.209 114.330 1.00 47.74  ? 167 ALA R O   1 
ATOM   1018 C  CB  . ALA A 1 288 ? 148.671 142.662 116.682 1.00 48.04  ? 167 ALA R CB  1 
ATOM   1019 N  N   . ILE A 1 289 ? 145.529 142.428 116.239 1.00 49.12  ? 168 ILE R N   1 
ATOM   1020 C  CA  . ILE A 1 289 ? 144.365 141.872 115.555 1.00 46.10  ? 168 ILE R CA  1 
ATOM   1021 C  C   . ILE A 1 289 ? 143.641 142.967 114.792 1.00 47.83  ? 168 ILE R C   1 
ATOM   1022 O  O   . ILE A 1 289 ? 143.342 142.828 113.601 1.00 48.47  ? 168 ILE R O   1 
ATOM   1023 C  CB  . ILE A 1 289 ? 143.422 141.186 116.561 1.00 44.79  ? 168 ILE R CB  1 
ATOM   1024 C  CG1 . ILE A 1 289 ? 143.898 139.777 116.902 1.00 43.62  ? 168 ILE R CG1 1 
ATOM   1025 C  CG2 . ILE A 1 289 ? 142.007 141.128 116.021 1.00 43.36  ? 168 ILE R CG2 1 
ATOM   1026 C  CD1 . ILE A 1 289 ? 143.134 139.163 118.047 1.00 42.90  ? 168 ILE R CD1 1 
ATOM   1027 N  N   . TRP A 1 290 ? 143.373 144.089 115.465 1.00 51.70  ? 169 TRP R N   1 
ATOM   1028 C  CA  . TRP A 1 290 ? 142.593 145.148 114.829 1.00 47.37  ? 169 TRP R CA  1 
ATOM   1029 C  C   . TRP A 1 290 ? 143.367 145.824 113.701 1.00 47.19  ? 169 TRP R C   1 
ATOM   1030 O  O   . TRP A 1 290 ? 142.787 146.157 112.663 1.00 48.92  ? 169 TRP R O   1 
ATOM   1031 C  CB  . TRP A 1 290 ? 142.146 146.166 115.869 1.00 42.91  ? 169 TRP R CB  1 
ATOM   1032 C  CG  . TRP A 1 290 ? 140.854 145.804 116.513 1.00 43.14  ? 169 TRP R CG  1 
ATOM   1033 C  CD1 . TRP A 1 290 ? 140.684 145.221 117.727 1.00 45.68  ? 169 TRP R CD1 1 
ATOM   1034 C  CD2 . TRP A 1 290 ? 139.545 146.004 115.977 1.00 44.94  ? 169 TRP R CD2 1 
ATOM   1035 N  NE1 . TRP A 1 290 ? 139.349 145.045 117.987 1.00 44.46  ? 169 TRP R NE1 1 
ATOM   1036 C  CE2 . TRP A 1 290 ? 138.629 145.519 116.925 1.00 45.88  ? 169 TRP R CE2 1 
ATOM   1037 C  CE3 . TRP A 1 290 ? 139.058 146.544 114.787 1.00 42.99  ? 169 TRP R CE3 1 
ATOM   1038 C  CZ2 . TRP A 1 290 ? 137.259 145.560 116.723 1.00 46.50  ? 169 TRP R CZ2 1 
ATOM   1039 C  CZ3 . TRP A 1 290 ? 137.700 146.584 114.588 1.00 44.10  ? 169 TRP R CZ3 1 
ATOM   1040 C  CH2 . TRP A 1 290 ? 136.815 146.096 115.549 1.00 48.43  ? 169 TRP R CH2 1 
ATOM   1041 N  N   . VAL A 1 291 ? 144.676 146.024 113.872 1.00 51.05  ? 170 VAL R N   1 
ATOM   1042 C  CA  . VAL A 1 291 ? 145.476 146.646 112.818 1.00 51.85  ? 170 VAL R CA  1 
ATOM   1043 C  C   . VAL A 1 291 ? 145.499 145.768 111.572 1.00 52.76  ? 170 VAL R C   1 
ATOM   1044 O  O   . VAL A 1 291 ? 145.265 146.241 110.450 1.00 57.04  ? 170 VAL R O   1 
ATOM   1045 C  CB  . VAL A 1 291 ? 146.900 146.934 113.327 1.00 53.33  ? 170 VAL R CB  1 
ATOM   1046 C  CG1 . VAL A 1 291 ? 147.868 147.046 112.164 1.00 52.79  ? 170 VAL R CG1 1 
ATOM   1047 C  CG2 . VAL A 1 291 ? 146.921 148.199 114.166 1.00 52.29  ? 170 VAL R CG2 1 
ATOM   1048 N  N   . CYS A 1 292 ? 145.785 144.474 111.748 1.00 53.66  ? 171 CYS R N   1 
ATOM   1049 C  CA  . CYS A 1 292 ? 145.825 143.566 110.606 1.00 53.95  ? 171 CYS R CA  1 
ATOM   1050 C  C   . CYS A 1 292 ? 144.461 143.458 109.937 1.00 56.84  ? 171 CYS R C   1 
ATOM   1051 O  O   . CYS A 1 292 ? 144.367 143.439 108.704 1.00 56.80  ? 171 CYS R O   1 
ATOM   1052 C  CB  . CYS A 1 292 ? 146.316 142.189 111.047 1.00 57.49  ? 171 CYS R CB  1 
ATOM   1053 S  SG  . CYS A 1 292 ? 147.974 142.175 111.752 1.00 71.00  ? 171 CYS R SG  1 
ATOM   1054 N  N   . CYS A 1 293 ? 143.389 143.396 110.734 1.00 57.02  ? 172 CYS R N   1 
ATOM   1055 C  CA  . CYS A 1 293 ? 142.048 143.314 110.169 1.00 52.80  ? 172 CYS R CA  1 
ATOM   1056 C  C   . CYS A 1 293 ? 141.705 144.557 109.361 1.00 55.69  ? 172 CYS R C   1 
ATOM   1057 O  O   . CYS A 1 293 ? 141.142 144.452 108.268 1.00 58.45  ? 172 CYS R O   1 
ATOM   1058 C  CB  . CYS A 1 293 ? 141.027 143.102 111.283 1.00 50.92  ? 172 CYS R CB  1 
ATOM   1059 S  SG  . CYS A 1 293 ? 141.066 141.452 111.991 1.00 63.94  ? 172 CYS R SG  1 
ATOM   1060 N  N   . GLY A 1 294 ? 142.032 145.742 109.877 1.00 57.49  ? 173 GLY R N   1 
ATOM   1061 C  CA  . GLY A 1 294 ? 141.742 146.959 109.137 1.00 57.28  ? 173 GLY R CA  1 
ATOM   1062 C  C   . GLY A 1 294 ? 142.513 147.050 107.835 1.00 59.06  ? 173 GLY R C   1 
ATOM   1063 O  O   . GLY A 1 294 ? 141.950 147.399 106.789 1.00 61.35  ? 173 GLY R O   1 
ATOM   1064 N  N   . VAL A 1 295 ? 143.808 146.732 107.875 1.00 60.54  ? 174 VAL R N   1 
ATOM   1065 C  CA  . VAL A 1 295 ? 144.607 146.766 106.654 1.00 60.31  ? 174 VAL R CA  1 
ATOM   1066 C  C   . VAL A 1 295 ? 144.045 145.790 105.629 1.00 63.97  ? 174 VAL R C   1 
ATOM   1067 O  O   . VAL A 1 295 ? 143.873 146.128 104.450 1.00 67.79  ? 174 VAL R O   1 
ATOM   1068 C  CB  . VAL A 1 295 ? 146.082 146.463 106.965 1.00 60.20  ? 174 VAL R CB  1 
ATOM   1069 C  CG1 . VAL A 1 295 ? 146.846 146.198 105.681 1.00 59.91  ? 174 VAL R CG1 1 
ATOM   1070 C  CG2 . VAL A 1 295 ? 146.705 147.611 107.735 1.00 62.27  ? 174 VAL R CG2 1 
ATOM   1071 N  N   . CYS A 1 296 ? 143.735 144.566 106.068 1.00 65.90  ? 175 CYS R N   1 
ATOM   1072 C  CA  . CYS A 1 296 ? 143.207 143.564 105.152 1.00 63.90  ? 175 CYS R CA  1 
ATOM   1073 C  C   . CYS A 1 296 ? 141.870 143.996 104.572 1.00 66.02  ? 175 CYS R C   1 
ATOM   1074 O  O   . CYS A 1 296 ? 141.616 143.798 103.383 1.00 70.52  ? 175 CYS R O   1 
ATOM   1075 C  CB  . CYS A 1 296 ? 143.071 142.219 105.863 1.00 64.45  ? 175 CYS R CB  1 
ATOM   1076 S  SG  . CYS A 1 296 ? 144.612 141.297 106.021 1.00 72.80  ? 175 CYS R SG  1 
ATOM   1077 N  N   . GLY A 1 297 ? 140.999 144.580 105.394 1.00 64.86  ? 176 GLY R N   1 
ATOM   1078 C  CA  . GLY A 1 297 ? 139.702 145.005 104.892 1.00 63.33  ? 176 GLY R CA  1 
ATOM   1079 C  C   . GLY A 1 297 ? 139.811 146.088 103.838 1.00 66.87  ? 176 GLY R C   1 
ATOM   1080 O  O   . GLY A 1 297 ? 139.169 146.017 102.786 1.00 69.34  ? 176 GLY R O   1 
ATOM   1081 N  N   . VAL A 1 298 ? 140.634 147.105 104.100 1.00 71.70  ? 177 VAL R N   1 
ATOM   1082 C  CA  . VAL A 1 298 ? 140.792 148.173 103.115 1.00 70.57  ? 177 VAL R CA  1 
ATOM   1083 C  C   . VAL A 1 298 ? 141.396 147.626 101.827 1.00 70.71  ? 177 VAL R C   1 
ATOM   1084 O  O   . VAL A 1 298 ? 140.942 147.958 100.723 1.00 73.15  ? 177 VAL R O   1 
ATOM   1085 C  CB  . VAL A 1 298 ? 141.630 149.327 103.693 1.00 73.08  ? 177 VAL R CB  1 
ATOM   1086 C  CG1 . VAL A 1 298 ? 141.828 150.403 102.645 1.00 71.57  ? 177 VAL R CG1 1 
ATOM   1087 C  CG2 . VAL A 1 298 ? 140.953 149.908 104.918 1.00 71.12  ? 177 VAL R CG2 1 
ATOM   1088 N  N   . VAL A 1 299 ? 142.415 146.766 101.940 1.00 70.47  ? 178 VAL R N   1 
ATOM   1089 C  CA  . VAL A 1 299 ? 143.054 146.218 100.745 1.00 70.75  ? 178 VAL R CA  1 
ATOM   1090 C  C   . VAL A 1 299 ? 142.080 145.350 99.955  1.00 74.48  ? 178 VAL R C   1 
ATOM   1091 O  O   . VAL A 1 299 ? 142.042 145.403 98.720  1.00 75.02  ? 178 VAL R O   1 
ATOM   1092 C  CB  . VAL A 1 299 ? 144.324 145.439 101.127 1.00 69.24  ? 178 VAL R CB  1 
ATOM   1093 C  CG1 . VAL A 1 299 ? 144.841 144.664 99.936  1.00 71.65  ? 178 VAL R CG1 1 
ATOM   1094 C  CG2 . VAL A 1 299 ? 145.381 146.388 101.634 1.00 71.03  ? 178 VAL R CG2 1 
ATOM   1095 N  N   . PHE A 1 300 ? 141.285 144.531 100.648 1.00 77.60  ? 179 PHE R N   1 
ATOM   1096 C  CA  . PHE A 1 300 ? 140.305 143.689 99.970  1.00 74.58  ? 179 PHE R CA  1 
ATOM   1097 C  C   . PHE A 1 300 ? 139.280 144.534 99.234  1.00 73.61  ? 179 PHE R C   1 
ATOM   1098 O  O   . PHE A 1 300 ? 138.961 144.271 98.070  1.00 75.09  ? 179 PHE R O   1 
ATOM   1099 C  CB  . PHE A 1 300 ? 139.598 142.781 100.978 1.00 71.13  ? 179 PHE R CB  1 
ATOM   1100 C  CG  . PHE A 1 300 ? 140.446 141.665 101.502 1.00 71.15  ? 179 PHE R CG  1 
ATOM   1101 C  CD1 . PHE A 1 300 ? 141.536 141.207 100.790 1.00 72.91  ? 179 PHE R CD1 1 
ATOM   1102 C  CD2 . PHE A 1 300 ? 140.145 141.068 102.710 1.00 70.33  ? 179 PHE R CD2 1 
ATOM   1103 C  CE1 . PHE A 1 300 ? 142.311 140.181 101.276 1.00 73.10  ? 179 PHE R CE1 1 
ATOM   1104 C  CE2 . PHE A 1 300 ? 140.916 140.045 103.200 1.00 71.81  ? 179 PHE R CE2 1 
ATOM   1105 C  CZ  . PHE A 1 300 ? 142.000 139.599 102.482 1.00 73.55  ? 179 PHE R CZ  1 
ATOM   1106 N  N   . ILE A 1 301 ? 138.753 145.561 99.901  1.00 76.81  ? 180 ILE R N   1 
ATOM   1107 C  CA  . ILE A 1 301 ? 137.673 146.343 99.314  1.00 75.95  ? 180 ILE R CA  1 
ATOM   1108 C  C   . ILE A 1 301 ? 138.174 147.152 98.124  1.00 77.67  ? 180 ILE R C   1 
ATOM   1109 O  O   . ILE A 1 301 ? 137.468 147.301 97.120  1.00 78.92  ? 180 ILE R O   1 
ATOM   1110 C  CB  . ILE A 1 301 ? 137.030 147.234 100.389 1.00 79.21  ? 180 ILE R CB  1 
ATOM   1111 C  CG1 . ILE A 1 301 ? 135.950 146.448 101.133 1.00 78.80  ? 180 ILE R CG1 1 
ATOM   1112 C  CG2 . ILE A 1 301 ? 136.473 148.510 99.779  1.00 80.56  ? 180 ILE R CG2 1 
ATOM   1113 C  CD1 . ILE A 1 301 ? 134.749 146.125 100.300 1.00 77.90  ? 180 ILE R CD1 1 
ATOM   1114 N  N   . VAL A 1 302 ? 139.397 147.679 98.207  1.00 85.15  ? 181 VAL R N   1 
ATOM   1115 C  CA  . VAL A 1 302 ? 139.936 148.463 97.097  1.00 86.99  ? 181 VAL R CA  1 
ATOM   1116 C  C   . VAL A 1 302 ? 140.037 147.607 95.839  1.00 85.99  ? 181 VAL R C   1 
ATOM   1117 O  O   . VAL A 1 302 ? 139.634 148.026 94.747  1.00 86.68  ? 181 VAL R O   1 
ATOM   1118 C  CB  . VAL A 1 302 ? 141.296 149.072 97.477  1.00 84.49  ? 181 VAL R CB  1 
ATOM   1119 C  CG1 . VAL A 1 302 ? 142.060 149.475 96.234  1.00 83.68  ? 181 VAL R CG1 1 
ATOM   1120 C  CG2 . VAL A 1 302 ? 141.100 150.268 98.386  1.00 83.93  ? 181 VAL R CG2 1 
ATOM   1121 N  N   . TYR A 1 303 ? 140.559 146.388 95.974  1.00 85.88  ? 182 TYR R N   1 
ATOM   1122 C  CA  . TYR A 1 303 ? 140.711 145.467 94.854  1.00 86.52  ? 182 TYR R CA  1 
ATOM   1123 C  C   . TYR A 1 303 ? 139.566 144.466 94.766  1.00 87.58  ? 182 TYR R C   1 
ATOM   1124 O  O   . TYR A 1 303 ? 139.754 143.349 94.275  1.00 88.94  ? 182 TYR R O   1 
ATOM   1125 C  CB  . TYR A 1 303 ? 142.045 144.732 94.949  1.00 86.89  ? 182 TYR R CB  1 
ATOM   1126 C  CG  . TYR A 1 303 ? 143.238 145.649 94.900  1.00 87.91  ? 182 TYR R CG  1 
ATOM   1127 C  CD1 . TYR A 1 303 ? 143.222 146.794 94.121  1.00 87.84  ? 182 TYR R CD1 1 
ATOM   1128 C  CD2 . TYR A 1 303 ? 144.381 145.372 95.633  1.00 86.86  ? 182 TYR R CD2 1 
ATOM   1129 C  CE1 . TYR A 1 303 ? 144.308 147.639 94.072  1.00 86.57  ? 182 TYR R CE1 1 
ATOM   1130 C  CE2 . TYR A 1 303 ? 145.472 146.210 95.589  1.00 88.36  ? 182 TYR R CE2 1 
ATOM   1131 C  CZ  . TYR A 1 303 ? 145.430 147.341 94.807  1.00 87.99  ? 182 TYR R CZ  1 
ATOM   1132 O  OH  . TYR A 1 303 ? 146.515 148.181 94.761  1.00 88.65  ? 182 TYR R OH  1 
ATOM   1133 N  N   . SER A 1 304 ? 138.377 144.849 95.231  1.00 88.58  ? 183 SER R N   1 
ATOM   1134 C  CA  . SER A 1 304 ? 137.230 143.953 95.215  1.00 87.81  ? 183 SER R CA  1 
ATOM   1135 C  C   . SER A 1 304 ? 136.694 143.698 93.819  1.00 88.95  ? 183 SER R C   1 
ATOM   1136 O  O   . SER A 1 304 ? 135.864 142.800 93.653  1.00 90.97  ? 183 SER R O   1 
ATOM   1137 C  CB  . SER A 1 304 ? 136.111 144.523 96.079  1.00 88.59  ? 183 SER R CB  1 
ATOM   1138 O  OG  . SER A 1 304 ? 134.881 143.894 95.781  1.00 89.05  ? 183 SER R OG  1 
ATOM   1139 N  N   . GLU A 1 305 ? 137.139 144.460 92.824  1.00 102.60 ? 184 GLU R N   1 
ATOM   1140 C  CA  . GLU A 1 305 ? 136.556 144.406 91.490  1.00 104.03 ? 184 GLU R CA  1 
ATOM   1141 C  C   . GLU A 1 305 ? 136.711 143.032 90.854  1.00 104.82 ? 184 GLU R C   1 
ATOM   1142 O  O   . GLU A 1 305 ? 135.716 142.345 90.607  1.00 105.30 ? 184 GLU R O   1 
ATOM   1143 C  CB  . GLU A 1 305 ? 137.186 145.475 90.596  1.00 104.49 ? 184 GLU R CB  1 
ATOM   1144 C  CG  . GLU A 1 305 ? 137.492 146.785 91.312  1.00 104.77 ? 184 GLU R CG  1 
ATOM   1145 C  CD  . GLU A 1 305 ? 136.272 147.390 91.980  1.00 105.21 ? 184 GLU R CD  1 
ATOM   1146 O  OE1 . GLU A 1 305 ? 135.167 147.299 91.407  1.00 105.62 ? 184 GLU R OE1 1 
ATOM   1147 O  OE2 . GLU A 1 305 ? 136.419 147.960 93.080  1.00 103.89 ? 184 GLU R OE2 1 
ATOM   1148 N  N   . SER A 1 306 ? 137.948 142.619 90.581  1.00 112.55 ? 185 SER R N   1 
ATOM   1149 C  CA  . SER A 1 306 ? 138.161 141.344 89.911  1.00 113.39 ? 185 SER R CA  1 
ATOM   1150 C  C   . SER A 1 306 ? 139.368 140.574 90.435  1.00 112.07 ? 185 SER R C   1 
ATOM   1151 O  O   . SER A 1 306 ? 139.753 139.572 89.820  1.00 112.37 ? 185 SER R O   1 
ATOM   1152 C  CB  . SER A 1 306 ? 138.309 141.559 88.399  1.00 112.58 ? 185 SER R CB  1 
ATOM   1153 O  OG  . SER A 1 306 ? 137.295 142.415 87.903  1.00 112.39 ? 185 SER R OG  1 
ATOM   1154 N  N   . LYS A 1 307 ? 139.974 140.992 91.541  1.00 96.77  ? 186 LYS R N   1 
ATOM   1155 C  CA  . LYS A 1 307 ? 141.190 140.339 91.993  1.00 97.82  ? 186 LYS R CA  1 
ATOM   1156 C  C   . LYS A 1 307 ? 140.864 138.982 92.615  1.00 97.72  ? 186 LYS R C   1 
ATOM   1157 O  O   . LYS A 1 307 ? 139.713 138.542 92.663  1.00 97.31  ? 186 LYS R O   1 
ATOM   1158 C  CB  . LYS A 1 307 ? 141.942 141.230 92.980  1.00 97.41  ? 186 LYS R CB  1 
ATOM   1159 C  CG  . LYS A 1 307 ? 143.457 141.207 92.791  1.00 99.75  ? 186 LYS R CG  1 
ATOM   1160 C  CD  . LYS A 1 307 ? 144.191 141.854 93.955  1.00 99.15  ? 186 LYS R CD  1 
ATOM   1161 C  CE  . LYS A 1 307 ? 145.695 141.648 93.842  1.00 97.53  ? 186 LYS R CE  1 
ATOM   1162 N  NZ  . LYS A 1 307 ? 146.432 142.195 95.014  1.00 97.04  ? 186 LYS R NZ  1 
ATOM   1163 N  N   . MET A 1 308 ? 141.911 138.303 93.082  1.00 91.43  ? 187 MET R N   1 
ATOM   1164 C  CA  . MET A 1 308 ? 141.783 137.046 93.802  1.00 88.99  ? 187 MET R CA  1 
ATOM   1165 C  C   . MET A 1 308 ? 141.633 137.250 95.304  1.00 87.23  ? 187 MET R C   1 
ATOM   1166 O  O   . MET A 1 308 ? 141.851 136.309 96.075  1.00 86.51  ? 187 MET R O   1 
ATOM   1167 C  CB  . MET A 1 308 ? 142.980 136.141 93.500  1.00 89.02  ? 187 MET R CB  1 
ATOM   1168 C  CG  . MET A 1 308 ? 144.277 136.555 94.180  1.00 89.18  ? 187 MET R CG  1 
ATOM   1169 S  SD  . MET A 1 308 ? 145.350 135.150 94.528  1.00 92.92  ? 187 MET R SD  1 
ATOM   1170 C  CE  . MET A 1 308 ? 145.314 134.300 92.953  1.00 88.30  ? 187 MET R CE  1 
ATOM   1171 N  N   . VAL A 1 309 ? 141.252 138.454 95.736  1.00 83.27  ? 188 VAL R N   1 
ATOM   1172 C  CA  . VAL A 1 309 ? 140.989 138.710 97.142  1.00 82.23  ? 188 VAL R CA  1 
ATOM   1173 C  C   . VAL A 1 309 ? 139.810 137.906 97.665  1.00 81.99  ? 188 VAL R C   1 
ATOM   1174 O  O   . VAL A 1 309 ? 139.601 137.846 98.877  1.00 82.93  ? 188 VAL R O   1 
ATOM   1175 C  CB  . VAL A 1 309 ? 140.751 140.215 97.384  1.00 82.78  ? 188 VAL R CB  1 
ATOM   1176 C  CG1 . VAL A 1 309 ? 141.939 141.020 96.900  1.00 83.38  ? 188 VAL R CG1 1 
ATOM   1177 C  CG2 . VAL A 1 309 ? 139.481 140.660 96.697  1.00 83.55  ? 188 VAL R CG2 1 
ATOM   1178 N  N   . ILE A 1 310 ? 139.017 137.307 96.776  1.00 77.28  ? 189 ILE R N   1 
ATOM   1179 C  CA  . ILE A 1 310 ? 138.014 136.343 97.212  1.00 77.49  ? 189 ILE R CA  1 
ATOM   1180 C  C   . ILE A 1 310 ? 138.683 135.059 97.689  1.00 78.71  ? 189 ILE R C   1 
ATOM   1181 O  O   . ILE A 1 310 ? 138.313 134.499 98.727  1.00 77.80  ? 189 ILE R O   1 
ATOM   1182 C  CB  . ILE A 1 310 ? 137.011 136.072 96.079  1.00 76.07  ? 189 ILE R CB  1 
ATOM   1183 C  CG1 . ILE A 1 310 ? 136.116 137.288 95.858  1.00 74.94  ? 189 ILE R CG1 1 
ATOM   1184 C  CG2 . ILE A 1 310 ? 136.181 134.855 96.396  1.00 77.31  ? 189 ILE R CG2 1 
ATOM   1185 C  CD1 . ILE A 1 310 ? 135.155 137.124 94.709  1.00 76.02  ? 189 ILE R CD1 1 
ATOM   1186 N  N   . VAL A 1 311 ? 139.684 134.580 96.947  1.00 77.94  ? 190 VAL R N   1 
ATOM   1187 C  CA  . VAL A 1 311 ? 140.388 133.360 97.335  1.00 75.13  ? 190 VAL R CA  1 
ATOM   1188 C  C   . VAL A 1 311 ? 141.100 133.556 98.666  1.00 73.58  ? 190 VAL R C   1 
ATOM   1189 O  O   . VAL A 1 311 ? 141.126 132.656 99.512  1.00 73.84  ? 190 VAL R O   1 
ATOM   1190 C  CB  . VAL A 1 311 ? 141.363 132.929 96.225  1.00 75.49  ? 190 VAL R CB  1 
ATOM   1191 C  CG1 . VAL A 1 311 ? 142.300 131.851 96.727  1.00 73.53  ? 190 VAL R CG1 1 
ATOM   1192 C  CG2 . VAL A 1 311 ? 140.594 132.442 95.014  1.00 75.99  ? 190 VAL R CG2 1 
ATOM   1193 N  N   . CYS A 1 312 ? 141.684 134.734 98.876  1.00 71.94  ? 191 CYS R N   1 
ATOM   1194 C  CA  . CYS A 1 312 ? 142.305 135.032 100.158 1.00 72.06  ? 191 CYS R CA  1 
ATOM   1195 C  C   . CYS A 1 312 ? 141.288 135.259 101.264 1.00 71.29  ? 191 CYS R C   1 
ATOM   1196 O  O   . CYS A 1 312 ? 141.676 135.309 102.433 1.00 71.69  ? 191 CYS R O   1 
ATOM   1197 C  CB  . CYS A 1 312 ? 143.203 136.263 100.039 1.00 72.40  ? 191 CYS R CB  1 
ATOM   1198 S  SG  . CYS A 1 312 ? 143.978 136.472 98.426  1.00 83.99  ? 191 CYS R SG  1 
ATOM   1199 N  N   . LEU A 1 313 ? 140.007 135.398 100.932 1.00 66.20  ? 192 LEU R N   1 
ATOM   1200 C  CA  . LEU A 1 313 ? 138.988 135.707 101.924 1.00 61.04  ? 192 LEU R CA  1 
ATOM   1201 C  C   . LEU A 1 313 ? 138.250 134.482 102.430 1.00 61.59  ? 192 LEU R C   1 
ATOM   1202 O  O   . LEU A 1 313 ? 137.762 134.495 103.563 1.00 63.64  ? 192 LEU R O   1 
ATOM   1203 C  CB  . LEU A 1 313 ? 137.973 136.697 101.346 1.00 63.41  ? 192 LEU R CB  1 
ATOM   1204 C  CG  . LEU A 1 313 ? 137.142 137.513 102.331 1.00 64.01  ? 192 LEU R CG  1 
ATOM   1205 C  CD1 . LEU A 1 313 ? 137.980 137.928 103.515 1.00 64.01  ? 192 LEU R CD1 1 
ATOM   1206 C  CD2 . LEU A 1 313 ? 136.561 138.723 101.640 1.00 64.74  ? 192 LEU R CD2 1 
ATOM   1207 N  N   . ILE A 1 314 ? 138.150 133.428 101.628 1.00 58.69  ? 193 ILE R N   1 
ATOM   1208 C  CA  . ILE A 1 314 ? 137.432 132.230 102.045 1.00 57.54  ? 193 ILE R CA  1 
ATOM   1209 C  C   . ILE A 1 314 ? 138.351 131.252 102.769 1.00 57.90  ? 193 ILE R C   1 
ATOM   1210 O  O   . ILE A 1 314 ? 138.001 130.747 103.839 1.00 57.96  ? 193 ILE R O   1 
ATOM   1211 C  CB  . ILE A 1 314 ? 136.723 131.590 100.830 1.00 56.45  ? 193 ILE R CB  1 
ATOM   1212 C  CG1 . ILE A 1 314 ? 137.708 130.929 99.872  1.00 54.69  ? 193 ILE R CG1 1 
ATOM   1213 C  CG2 . ILE A 1 314 ? 135.924 132.635 100.087 1.00 59.52  ? 193 ILE R CG2 1 
ATOM   1214 C  CD1 . ILE A 1 314 ? 137.158 130.720 98.487  1.00 57.72  ? 193 ILE R CD1 1 
ATOM   1215 N  N   . THR A 1 315 ? 139.555 131.014 102.235 1.00 56.04  ? 194 THR R N   1 
ATOM   1216 C  CA  . THR A 1 315 ? 140.487 130.093 102.879 1.00 54.36  ? 194 THR R CA  1 
ATOM   1217 C  C   . THR A 1 315 ? 140.744 130.507 104.317 1.00 53.87  ? 194 THR R C   1 
ATOM   1218 O  O   . THR A 1 315 ? 140.629 129.688 105.237 1.00 54.06  ? 194 THR R O   1 
ATOM   1219 C  CB  . THR A 1 315 ? 141.800 130.031 102.104 1.00 51.96  ? 194 THR R CB  1 
ATOM   1220 O  OG1 . THR A 1 315 ? 142.458 131.298 102.186 1.00 56.78  ? 194 THR R OG1 1 
ATOM   1221 C  CG2 . THR A 1 315 ? 141.547 129.686 100.651 1.00 51.65  ? 194 THR R CG2 1 
ATOM   1222 N  N   . MET A 1 316 ? 141.056 131.789 104.530 1.00 49.53  ? 195 MET R N   1 
ATOM   1223 C  CA  . MET A 1 316 ? 141.162 132.344 105.872 1.00 47.81  ? 195 MET R CA  1 
ATOM   1224 C  C   . MET A 1 316 ? 140.052 131.805 106.761 1.00 48.81  ? 195 MET R C   1 
ATOM   1225 O  O   . MET A 1 316 ? 140.318 131.090 107.736 1.00 52.73  ? 195 MET R O   1 
ATOM   1226 C  CB  . MET A 1 316 ? 141.100 133.873 105.809 1.00 49.37  ? 195 MET R CB  1 
ATOM   1227 C  CG  . MET A 1 316 ? 142.422 134.562 105.532 1.00 51.81  ? 195 MET R CG  1 
ATOM   1228 S  SD  . MET A 1 316 ? 142.259 136.357 105.383 1.00 58.38  ? 195 MET R SD  1 
ATOM   1229 C  CE  . MET A 1 316 ? 141.943 136.839 107.075 1.00 46.59  ? 195 MET R CE  1 
ATOM   1230 N  N   . PHE A 1 317 ? 138.797 132.059 106.374 1.00 39.63  ? 196 PHE R N   1 
ATOM   1231 C  CA  . PHE A 1 317 ? 137.672 131.643 107.203 1.00 36.17  ? 196 PHE R CA  1 
ATOM   1232 C  C   . PHE A 1 317 ? 137.745 130.159 107.496 1.00 41.13  ? 196 PHE R C   1 
ATOM   1233 O  O   . PHE A 1 317 ? 137.700 129.742 108.660 1.00 46.91  ? 196 PHE R O   1 
ATOM   1234 C  CB  . PHE A 1 317 ? 136.346 131.974 106.526 1.00 37.01  ? 196 PHE R CB  1 
ATOM   1235 C  CG  . PHE A 1 317 ? 135.155 131.309 107.166 1.00 39.31  ? 196 PHE R CG  1 
ATOM   1236 C  CD1 . PHE A 1 317 ? 134.654 131.761 108.370 1.00 33.18  ? 196 PHE R CD1 1 
ATOM   1237 C  CD2 . PHE A 1 317 ? 134.533 130.236 106.558 1.00 41.30  ? 196 PHE R CD2 1 
ATOM   1238 C  CE1 . PHE A 1 317 ? 133.562 131.156 108.951 1.00 30.61  ? 196 PHE R CE1 1 
ATOM   1239 C  CE2 . PHE A 1 317 ? 133.442 129.630 107.140 1.00 37.25  ? 196 PHE R CE2 1 
ATOM   1240 C  CZ  . PHE A 1 317 ? 132.959 130.090 108.335 1.00 33.65  ? 196 PHE R CZ  1 
ATOM   1241 N  N   . PHE A 1 318 ? 137.920 129.347 106.451 1.00 39.87  ? 197 PHE R N   1 
ATOM   1242 C  CA  . PHE A 1 318 ? 137.958 127.907 106.654 1.00 38.00  ? 197 PHE R CA  1 
ATOM   1243 C  C   . PHE A 1 318 ? 139.016 127.552 107.680 1.00 41.66  ? 197 PHE R C   1 
ATOM   1244 O  O   . PHE A 1 318 ? 138.726 126.882 108.679 1.00 42.72  ? 197 PHE R O   1 
ATOM   1245 C  CB  . PHE A 1 318 ? 138.202 127.191 105.328 1.00 35.35  ? 197 PHE R CB  1 
ATOM   1246 C  CG  . PHE A 1 318 ? 136.980 127.102 104.459 1.00 43.60  ? 197 PHE R CG  1 
ATOM   1247 C  CD1 . PHE A 1 318 ? 135.741 127.488 104.942 1.00 46.66  ? 197 PHE R CD1 1 
ATOM   1248 C  CD2 . PHE A 1 318 ? 137.068 126.646 103.159 1.00 45.59  ? 197 PHE R CD2 1 
ATOM   1249 C  CE1 . PHE A 1 318 ? 134.611 127.413 104.148 1.00 43.93  ? 197 PHE R CE1 1 
ATOM   1250 C  CE2 . PHE A 1 318 ? 135.939 126.570 102.361 1.00 46.83  ? 197 PHE R CE2 1 
ATOM   1251 C  CZ  . PHE A 1 318 ? 134.710 126.956 102.859 1.00 43.35  ? 197 PHE R CZ  1 
ATOM   1252 N  N   . ALA A 1 319 ? 140.226 128.090 107.508 1.00 33.53  ? 198 ALA R N   1 
ATOM   1253 C  CA  . ALA A 1 319 ? 141.286 127.816 108.467 1.00 33.64  ? 198 ALA R CA  1 
ATOM   1254 C  C   . ALA A 1 319 ? 140.828 128.170 109.869 1.00 31.30  ? 198 ALA R C   1 
ATOM   1255 O  O   . ALA A 1 319 ? 140.834 127.324 110.770 1.00 31.87  ? 198 ALA R O   1 
ATOM   1256 C  CB  . ALA A 1 319 ? 142.547 128.592 108.095 1.00 34.92  ? 198 ALA R CB  1 
ATOM   1257 N  N   . MET A 1 320 ? 140.322 129.390 110.043 1.00 33.67  ? 199 MET R N   1 
ATOM   1258 C  CA  . MET A 1 320 ? 139.876 129.807 111.363 1.00 29.43  ? 199 MET R CA  1 
ATOM   1259 C  C   . MET A 1 320 ? 138.791 128.877 111.875 1.00 29.29  ? 199 MET R C   1 
ATOM   1260 O  O   . MET A 1 320 ? 138.860 128.407 113.017 1.00 38.07  ? 199 MET R O   1 
ATOM   1261 C  CB  . MET A 1 320 ? 139.381 131.248 111.314 1.00 27.74  ? 199 MET R CB  1 
ATOM   1262 C  CG  . MET A 1 320 ? 140.508 132.248 111.195 1.00 34.10  ? 199 MET R CG  1 
ATOM   1263 S  SD  . MET A 1 320 ? 140.195 133.817 111.997 1.00 53.45  ? 199 MET R SD  1 
ATOM   1264 C  CE  . MET A 1 320 ? 141.158 134.885 110.940 1.00 33.68  ? 199 MET R CE  1 
ATOM   1265 N  N   . MET A 1 321 ? 137.824 128.535 111.017 1.00 28.97  ? 200 MET R N   1 
ATOM   1266 C  CA  . MET A 1 321 ? 136.786 127.599 111.426 1.00 27.65  ? 200 MET R CA  1 
ATOM   1267 C  C   . MET A 1 321 ? 137.414 126.319 111.946 1.00 35.27  ? 200 MET R C   1 
ATOM   1268 O  O   . MET A 1 321 ? 137.156 125.904 113.084 1.00 37.79  ? 200 MET R O   1 
ATOM   1269 C  CB  . MET A 1 321 ? 135.847 127.292 110.260 1.00 29.11  ? 200 MET R CB  1 
ATOM   1270 C  CG  . MET A 1 321 ? 134.693 126.376 110.630 1.00 33.77  ? 200 MET R CG  1 
ATOM   1271 S  SD  . MET A 1 321 ? 133.512 126.093 109.300 1.00 49.18  ? 200 MET R SD  1 
ATOM   1272 C  CE  . MET A 1 321 ? 132.575 127.610 109.347 1.00 35.50  ? 200 MET R CE  1 
ATOM   1273 N  N   . LEU A 1 322 ? 138.319 125.731 111.155 1.00 27.62  ? 201 LEU R N   1 
ATOM   1274 C  CA  . LEU A 1 322 ? 138.963 124.492 111.567 1.00 24.09  ? 201 LEU R CA  1 
ATOM   1275 C  C   . LEU A 1 322 ? 139.544 124.642 112.957 1.00 24.32  ? 201 LEU R C   1 
ATOM   1276 O  O   . LEU A 1 322 ? 139.292 123.815 113.840 1.00 19.39  ? 201 LEU R O   1 
ATOM   1277 C  CB  . LEU A 1 322 ? 140.052 124.100 110.571 1.00 23.20  ? 201 LEU R CB  1 
ATOM   1278 C  CG  . LEU A 1 322 ? 139.647 123.148 109.447 1.00 26.06  ? 201 LEU R CG  1 
ATOM   1279 C  CD1 . LEU A 1 322 ? 140.749 123.065 108.412 1.00 29.70  ? 201 LEU R CD1 1 
ATOM   1280 C  CD2 . LEU A 1 322 ? 139.330 121.774 109.994 1.00 22.31  ? 201 LEU R CD2 1 
ATOM   1281 N  N   . LEU A 1 323 ? 140.253 125.751 113.193 1.00 26.38  ? 202 LEU R N   1 
ATOM   1282 C  CA  . LEU A 1 323 ? 140.910 125.936 114.477 1.00 16.56  ? 202 LEU R CA  1 
ATOM   1283 C  C   . LEU A 1 323 ? 139.909 125.813 115.608 1.00 11.75  ? 202 LEU R C   1 
ATOM   1284 O  O   . LEU A 1 323 ? 140.078 124.982 116.507 1.00 24.78  ? 202 LEU R O   1 
ATOM   1285 C  CB  . LEU A 1 323 ? 141.617 127.285 114.521 1.00 21.07  ? 202 LEU R CB  1 
ATOM   1286 C  CG  . LEU A 1 323 ? 143.142 127.224 114.509 1.00 26.97  ? 202 LEU R CG  1 
ATOM   1287 C  CD1 . LEU A 1 323 ? 143.733 128.571 114.878 1.00 24.56  ? 202 LEU R CD1 1 
ATOM   1288 C  CD2 . LEU A 1 323 ? 143.641 126.143 115.451 1.00 24.70  ? 202 LEU R CD2 1 
ATOM   1289 N  N   . MET A 1 324 ? 138.812 126.569 115.539 1.00 10.59  ? 203 MET R N   1 
ATOM   1290 C  CA  . MET A 1 324 ? 137.838 126.488 116.616 1.00 14.19  ? 203 MET R CA  1 
ATOM   1291 C  C   . MET A 1 324 ? 137.334 125.066 116.753 1.00 16.32  ? 203 MET R C   1 
ATOM   1292 O  O   . MET A 1 324 ? 137.369 124.486 117.844 1.00 26.09  ? 203 MET R O   1 
ATOM   1293 C  CB  . MET A 1 324 ? 136.680 127.453 116.378 1.00 16.13  ? 203 MET R CB  1 
ATOM   1294 C  CG  . MET A 1 324 ? 137.056 128.915 116.478 1.00 17.64  ? 203 MET R CG  1 
ATOM   1295 S  SD  . MET A 1 324 ? 135.675 130.007 116.104 1.00 41.47  ? 203 MET R SD  1 
ATOM   1296 C  CE  . MET A 1 324 ? 134.640 129.805 117.548 1.00 13.52  ? 203 MET R CE  1 
ATOM   1297 N  N   . GLY A 1 325 ? 136.976 124.449 115.627 1.00 16.11  ? 204 GLY R N   1 
ATOM   1298 C  CA  . GLY A 1 325 ? 136.438 123.104 115.676 1.00 19.13  ? 204 GLY R CA  1 
ATOM   1299 C  C   . GLY A 1 325 ? 137.381 122.134 116.352 1.00 17.32  ? 204 GLY R C   1 
ATOM   1300 O  O   . GLY A 1 325 ? 136.946 121.208 117.034 1.00 18.90  ? 204 GLY R O   1 
ATOM   1301 N  N   . THR A 1 326 ? 138.686 122.346 116.196 1.00 14.22  ? 205 THR R N   1 
ATOM   1302 C  CA  . THR A 1 326 ? 139.631 121.502 116.911 1.00 6.73   ? 205 THR R CA  1 
ATOM   1303 C  C   . THR A 1 326 ? 139.651 121.865 118.385 1.00 13.02  ? 205 THR R C   1 
ATOM   1304 O  O   . THR A 1 326 ? 139.336 121.035 119.245 1.00 18.28  ? 205 THR R O   1 
ATOM   1305 C  CB  . THR A 1 326 ? 141.027 121.629 116.306 1.00 11.65  ? 205 THR R CB  1 
ATOM   1306 O  OG1 . THR A 1 326 ? 141.001 121.191 114.946 1.00 22.49  ? 205 THR R OG1 1 
ATOM   1307 C  CG2 . THR A 1 326 ? 142.006 120.782 117.074 1.00 14.50  ? 205 THR R CG2 1 
ATOM   1308 N  N   . LEU A 1 327 ? 139.945 123.131 118.688 1.00 16.31  ? 206 LEU R N   1 
ATOM   1309 C  CA  . LEU A 1 327 ? 140.268 123.514 120.056 1.00 5.12   ? 206 LEU R CA  1 
ATOM   1310 C  C   . LEU A 1 327 ? 139.165 123.082 121.001 1.00 9.61   ? 206 LEU R C   1 
ATOM   1311 O  O   . LEU A 1 327 ? 139.364 122.214 121.857 1.00 20.73  ? 206 LEU R O   1 
ATOM   1312 C  CB  . LEU A 1 327 ? 140.487 125.025 120.142 1.00 8.70   ? 206 LEU R CB  1 
ATOM   1313 C  CG  . LEU A 1 327 ? 141.681 125.622 119.400 1.00 15.43  ? 206 LEU R CG  1 
ATOM   1314 C  CD1 . LEU A 1 327 ? 141.799 127.080 119.730 1.00 14.92  ? 206 LEU R CD1 1 
ATOM   1315 C  CD2 . LEU A 1 327 ? 142.964 124.904 119.738 1.00 11.68  ? 206 LEU R CD2 1 
ATOM   1316 N  N   . TYR A 1 328 ? 137.967 123.623 120.793 1.00 10.89  ? 207 TYR R N   1 
ATOM   1317 C  CA  . TYR A 1 328 ? 136.845 123.317 121.664 1.00 4.91   ? 207 TYR R CA  1 
ATOM   1318 C  C   . TYR A 1 328 ? 136.610 121.821 121.761 1.00 11.86  ? 207 TYR R C   1 
ATOM   1319 O  O   . TYR A 1 328 ? 136.419 121.294 122.862 1.00 28.66  ? 207 TYR R O   1 
ATOM   1320 C  CB  . TYR A 1 328 ? 135.598 124.034 121.167 1.00 7.62   ? 207 TYR R CB  1 
ATOM   1321 C  CG  . TYR A 1 328 ? 135.539 125.475 121.607 1.00 17.97  ? 207 TYR R CG  1 
ATOM   1322 C  CD1 . TYR A 1 328 ? 135.615 125.813 122.948 1.00 19.15  ? 207 TYR R CD1 1 
ATOM   1323 C  CD2 . TYR A 1 328 ? 135.418 126.497 120.686 1.00 11.62  ? 207 TYR R CD2 1 
ATOM   1324 C  CE1 . TYR A 1 328 ? 135.567 127.124 123.353 1.00 14.71  ? 207 TYR R CE1 1 
ATOM   1325 C  CE2 . TYR A 1 328 ? 135.370 127.808 121.087 1.00 16.00  ? 207 TYR R CE2 1 
ATOM   1326 C  CZ  . TYR A 1 328 ? 135.445 128.115 122.419 1.00 14.21  ? 207 TYR R CZ  1 
ATOM   1327 O  OH  . TYR A 1 328 ? 135.394 129.423 122.822 1.00 20.59  ? 207 TYR R OH  1 
ATOM   1328 N  N   . VAL A 1 329 ? 136.683 121.105 120.637 1.00 16.25  ? 208 VAL R N   1 
ATOM   1329 C  CA  . VAL A 1 329 ? 136.437 119.665 120.684 1.00 17.98  ? 208 VAL R CA  1 
ATOM   1330 C  C   . VAL A 1 329 ? 137.428 119.000 121.626 1.00 13.85  ? 208 VAL R C   1 
ATOM   1331 O  O   . VAL A 1 329 ? 137.040 118.266 122.543 1.00 10.12  ? 208 VAL R O   1 
ATOM   1332 C  CB  . VAL A 1 329 ? 136.488 119.054 119.272 1.00 14.65  ? 208 VAL R CB  1 
ATOM   1333 C  CG1 . VAL A 1 329 ? 136.912 117.601 119.332 1.00 15.07  ? 208 VAL R CG1 1 
ATOM   1334 C  CG2 . VAL A 1 329 ? 135.135 119.167 118.609 1.00 8.62   ? 208 VAL R CG2 1 
ATOM   1335 N  N   . HIS A 1 330 ? 138.715 119.319 121.472 1.00 9.79   ? 209 HIS R N   1 
ATOM   1336 C  CA  . HIS A 1 330 ? 139.713 118.778 122.383 1.00 10.06  ? 209 HIS R CA  1 
ATOM   1337 C  C   . HIS A 1 330 ? 139.352 119.107 123.822 1.00 8.83   ? 209 HIS R C   1 
ATOM   1338 O  O   . HIS A 1 330 ? 139.312 118.218 124.680 1.00 19.14  ? 209 HIS R O   1 
ATOM   1339 C  CB  . HIS A 1 330 ? 141.095 119.319 122.034 1.00 14.62  ? 209 HIS R CB  1 
ATOM   1340 C  CG  . HIS A 1 330 ? 142.214 118.597 122.712 1.00 17.58  ? 209 HIS R CG  1 
ATOM   1341 N  ND1 . HIS A 1 330 ? 143.534 118.946 122.538 1.00 17.45  ? 209 HIS R ND1 1 
ATOM   1342 C  CD2 . HIS A 1 330 ? 142.212 117.547 123.563 1.00 17.46  ? 209 HIS R CD2 1 
ATOM   1343 C  CE1 . HIS A 1 330 ? 144.298 118.139 123.250 1.00 14.27  ? 209 HIS R CE1 1 
ATOM   1344 N  NE2 . HIS A 1 330 ? 143.520 117.281 123.882 1.00 21.19  ? 209 HIS R NE2 1 
ATOM   1345 N  N   . MET A 1 331 ? 139.008 120.371 124.086 1.00 8.11   ? 210 MET R N   1 
ATOM   1346 C  CA  . MET A 1 331 ? 138.632 120.762 125.437 1.00 13.64  ? 210 MET R CA  1 
ATOM   1347 C  C   . MET A 1 331 ? 137.548 119.841 125.964 1.00 12.83  ? 210 MET R C   1 
ATOM   1348 O  O   . MET A 1 331 ? 137.690 119.243 127.036 1.00 23.56  ? 210 MET R O   1 
ATOM   1349 C  CB  . MET A 1 331 ? 138.157 122.214 125.460 1.00 11.99  ? 210 MET R CB  1 
ATOM   1350 C  CG  . MET A 1 331 ? 139.226 123.240 125.785 1.00 12.46  ? 210 MET R CG  1 
ATOM   1351 S  SD  . MET A 1 331 ? 138.542 124.901 125.799 1.00 31.63  ? 210 MET R SD  1 
ATOM   1352 C  CE  . MET A 1 331 ? 139.384 125.633 124.408 1.00 11.10  ? 210 MET R CE  1 
ATOM   1353 N  N   . PHE A 1 332 ? 136.498 119.633 125.168 1.00 10.41  ? 211 PHE R N   1 
ATOM   1354 C  CA  . PHE A 1 332 ? 135.394 118.802 125.624 1.00 14.34  ? 211 PHE R CA  1 
ATOM   1355 C  C   . PHE A 1 332 ? 135.878 117.405 125.963 1.00 17.74  ? 211 PHE R C   1 
ATOM   1356 O  O   . PHE A 1 332 ? 135.572 116.876 127.037 1.00 28.33  ? 211 PHE R O   1 
ATOM   1357 C  CB  . PHE A 1 332 ? 134.299 118.744 124.565 1.00 16.19  ? 211 PHE R CB  1 
ATOM   1358 C  CG  . PHE A 1 332 ? 133.173 117.824 124.916 1.00 18.98  ? 211 PHE R CG  1 
ATOM   1359 C  CD1 . PHE A 1 332 ? 132.443 118.020 126.068 1.00 15.83  ? 211 PHE R CD1 1 
ATOM   1360 C  CD2 . PHE A 1 332 ? 132.847 116.761 124.096 1.00 20.36  ? 211 PHE R CD2 1 
ATOM   1361 C  CE1 . PHE A 1 332 ? 131.412 117.177 126.389 1.00 23.42  ? 211 PHE R CE1 1 
ATOM   1362 C  CE2 . PHE A 1 332 ? 131.816 115.916 124.416 1.00 18.09  ? 211 PHE R CE2 1 
ATOM   1363 C  CZ  . PHE A 1 332 ? 131.098 116.124 125.559 1.00 20.65  ? 211 PHE R CZ  1 
ATOM   1364 N  N   . LEU A 1 333 ? 136.690 116.812 125.087 1.00 10.67  ? 212 LEU R N   1 
ATOM   1365 C  CA  . LEU A 1 333 ? 137.148 115.457 125.354 1.00 11.38  ? 212 LEU R CA  1 
ATOM   1366 C  C   . LEU A 1 333 ? 137.906 115.406 126.667 1.00 13.79  ? 212 LEU R C   1 
ATOM   1367 O  O   . LEU A 1 333 ? 137.678 114.509 127.488 1.00 22.00  ? 212 LEU R O   1 
ATOM   1368 C  CB  . LEU A 1 333 ? 138.011 114.948 124.202 1.00 17.54  ? 212 LEU R CB  1 
ATOM   1369 C  CG  . LEU A 1 333 ? 137.281 114.654 122.888 1.00 16.10  ? 212 LEU R CG  1 
ATOM   1370 C  CD1 . LEU A 1 333 ? 138.179 113.888 121.940 1.00 10.32  ? 212 LEU R CD1 1 
ATOM   1371 C  CD2 . LEU A 1 333 ? 135.992 113.900 123.130 1.00 10.15  ? 212 LEU R CD2 1 
ATOM   1372 N  N   . PHE A 1 334 ? 138.746 116.410 126.921 1.00 14.49  ? 213 PHE R N   1 
ATOM   1373 C  CA  . PHE A 1 334 ? 139.487 116.450 128.175 1.00 8.13   ? 213 PHE R CA  1 
ATOM   1374 C  C   . PHE A 1 334 ? 138.533 116.450 129.355 1.00 10.52  ? 213 PHE R C   1 
ATOM   1375 O  O   . PHE A 1 334 ? 138.688 115.663 130.294 1.00 16.19  ? 213 PHE R O   1 
ATOM   1376 C  CB  . PHE A 1 334 ? 140.379 117.685 128.202 1.00 6.77   ? 213 PHE R CB  1 
ATOM   1377 C  CG  . PHE A 1 334 ? 141.402 117.671 129.288 1.00 18.72  ? 213 PHE R CG  1 
ATOM   1378 C  CD1 . PHE A 1 334 ? 142.178 116.555 129.511 1.00 16.17  ? 213 PHE R CD1 1 
ATOM   1379 C  CD2 . PHE A 1 334 ? 141.600 118.785 130.080 1.00 19.02  ? 213 PHE R CD2 1 
ATOM   1380 C  CE1 . PHE A 1 334 ? 143.119 116.550 130.504 1.00 17.44  ? 213 PHE R CE1 1 
ATOM   1381 C  CE2 . PHE A 1 334 ? 142.538 118.779 131.064 1.00 10.64  ? 213 PHE R CE2 1 
ATOM   1382 C  CZ  . PHE A 1 334 ? 143.298 117.662 131.277 1.00 14.10  ? 213 PHE R CZ  1 
ATOM   1383 N  N   . ALA A 1 335 ? 137.498 117.287 129.289 1.00 7.65   ? 214 ALA R N   1 
ATOM   1384 C  CA  . ALA A 1 335 ? 136.548 117.363 130.386 1.00 3.82   ? 214 ALA R CA  1 
ATOM   1385 C  C   . ALA A 1 335 ? 135.934 116.004 130.657 1.00 12.40  ? 214 ALA R C   1 
ATOM   1386 O  O   . ALA A 1 335 ? 135.744 115.622 131.816 1.00 23.89  ? 214 ALA R O   1 
ATOM   1387 C  CB  . ALA A 1 335 ? 135.468 118.395 130.075 1.00 10.40  ? 214 ALA R CB  1 
ATOM   1388 N  N   . ARG A 1 336 ? 135.677 115.231 129.600 1.00 12.72  ? 215 ARG R N   1 
ATOM   1389 C  CA  . ARG A 1 336 ? 135.070 113.920 129.787 1.00 18.13  ? 215 ARG R CA  1 
ATOM   1390 C  C   . ARG A 1 336 ? 135.956 113.028 130.643 1.00 19.60  ? 215 ARG R C   1 
ATOM   1391 O  O   . ARG A 1 336 ? 135.466 112.346 131.550 1.00 18.05  ? 215 ARG R O   1 
ATOM   1392 C  CB  . ARG A 1 336 ? 134.791 113.277 128.434 1.00 20.06  ? 215 ARG R CB  1 
ATOM   1393 C  CG  . ARG A 1 336 ? 133.486 113.717 127.816 1.00 20.09  ? 215 ARG R CG  1 
ATOM   1394 C  CD  . ARG A 1 336 ? 132.752 112.539 127.219 1.00 23.20  ? 215 ARG R CD  1 
ATOM   1395 N  NE  . ARG A 1 336 ? 133.673 111.596 126.600 1.00 27.59  ? 215 ARG R NE  1 
ATOM   1396 C  CZ  . ARG A 1 336 ? 133.394 110.322 126.365 1.00 29.69  ? 215 ARG R CZ  1 
ATOM   1397 N  NH1 . ARG A 1 336 ? 132.221 109.802 126.682 1.00 24.74  ? 215 ARG R NH1 1 
ATOM   1398 N  NH2 . ARG A 1 336 ? 134.316 109.551 125.797 1.00 27.70  ? 215 ARG R NH2 1 
ATOM   1399 N  N   . LEU A 1 337 ? 137.268 113.053 130.395 1.00 16.96  ? 216 LEU R N   1 
ATOM   1400 C  CA  . LEU A 1 337 ? 138.193 112.293 131.226 1.00 16.79  ? 216 LEU R CA  1 
ATOM   1401 C  C   . LEU A 1 337 ? 138.000 112.627 132.695 1.00 20.16  ? 216 LEU R C   1 
ATOM   1402 O  O   . LEU A 1 337 ? 137.925 111.728 133.538 1.00 29.53  ? 216 LEU R O   1 
ATOM   1403 C  CB  . LEU A 1 337 ? 139.632 112.576 130.804 1.00 18.52  ? 216 LEU R CB  1 
ATOM   1404 C  CG  . LEU A 1 337 ? 140.370 111.476 130.050 1.00 21.34  ? 216 LEU R CG  1 
ATOM   1405 C  CD1 . LEU A 1 337 ? 141.557 112.053 129.306 1.00 19.33  ? 216 LEU R CD1 1 
ATOM   1406 C  CD2 . LEU A 1 337 ? 140.820 110.405 131.015 1.00 21.21  ? 216 LEU R CD2 1 
ATOM   1407 N  N   . HIS A 1 338 ? 137.868 113.916 133.017 1.00 17.20  ? 217 HIS R N   1 
ATOM   1408 C  CA  . HIS A 1 338 ? 137.682 114.302 134.409 1.00 12.82  ? 217 HIS R CA  1 
ATOM   1409 C  C   . HIS A 1 338 ? 136.411 113.691 134.975 1.00 16.68  ? 217 HIS R C   1 
ATOM   1410 O  O   . HIS A 1 338 ? 136.415 113.170 136.094 1.00 34.29  ? 217 HIS R O   1 
ATOM   1411 C  CB  . HIS A 1 338 ? 137.659 115.822 134.537 1.00 17.77  ? 217 HIS R CB  1 
ATOM   1412 C  CG  . HIS A 1 338 ? 139.019 116.439 134.595 1.00 22.35  ? 217 HIS R CG  1 
ATOM   1413 N  ND1 . HIS A 1 338 ? 139.282 117.705 134.126 1.00 25.82  ? 217 HIS R ND1 1 
ATOM   1414 C  CD2 . HIS A 1 338 ? 140.194 115.960 135.064 1.00 23.86  ? 217 HIS R CD2 1 
ATOM   1415 C  CE1 . HIS A 1 338 ? 140.560 117.981 134.306 1.00 26.46  ? 217 HIS R CE1 1 
ATOM   1416 N  NE2 . HIS A 1 338 ? 141.136 116.940 134.876 1.00 22.03  ? 217 HIS R NE2 1 
ATOM   1417 N  N   . VAL A 1 339 ? 135.324 113.701 134.201 1.00 14.82  ? 218 VAL R N   1 
ATOM   1418 C  CA  . VAL A 1 339 ? 134.093 113.080 134.675 1.00 18.88  ? 218 VAL R CA  1 
ATOM   1419 C  C   . VAL A 1 339 ? 134.342 111.615 134.988 1.00 20.93  ? 218 VAL R C   1 
ATOM   1420 O  O   . VAL A 1 339 ? 133.863 111.089 135.998 1.00 27.85  ? 218 VAL R O   1 
ATOM   1421 C  CB  . VAL A 1 339 ? 132.962 113.251 133.643 1.00 25.63  ? 218 VAL R CB  1 
ATOM   1422 C  CG1 . VAL A 1 339 ? 131.731 112.489 134.084 1.00 24.41  ? 218 VAL R CG1 1 
ATOM   1423 C  CG2 . VAL A 1 339 ? 132.622 114.707 133.450 1.00 19.76  ? 218 VAL R CG2 1 
ATOM   1424 N  N   . LYS A 1 340 ? 135.137 110.947 134.152 1.00 20.20  ? 219 LYS R N   1 
ATOM   1425 C  CA  . LYS A 1 340 ? 135.380 109.525 134.335 1.00 21.00  ? 219 LYS R CA  1 
ATOM   1426 C  C   . LYS A 1 340 ? 136.141 109.232 135.617 1.00 25.82  ? 219 LYS R C   1 
ATOM   1427 O  O   . LYS A 1 340 ? 136.149 108.083 136.065 1.00 31.83  ? 219 LYS R O   1 
ATOM   1428 C  CB  . LYS A 1 340 ? 136.140 108.969 133.132 1.00 26.27  ? 219 LYS R CB  1 
ATOM   1429 N  N   . ARG A 1 341 ? 136.778 110.236 136.217 1.00 24.89  ? 220 ARG R N   1 
ATOM   1430 C  CA  . ARG A 1 341 ? 137.458 110.068 137.491 1.00 23.51  ? 220 ARG R CA  1 
ATOM   1431 C  C   . ARG A 1 341 ? 136.694 110.680 138.652 1.00 27.26  ? 220 ARG R C   1 
ATOM   1432 O  O   . ARG A 1 341 ? 137.136 110.556 139.797 1.00 40.17  ? 220 ARG R O   1 
ATOM   1433 C  CB  . ARG A 1 341 ? 138.866 110.666 137.429 1.00 19.48  ? 220 ARG R CB  1 
ATOM   1434 C  CG  . ARG A 1 341 ? 139.524 110.552 136.078 1.00 24.97  ? 220 ARG R CG  1 
ATOM   1435 C  CD  . ARG A 1 341 ? 141.011 110.816 136.171 1.00 31.71  ? 220 ARG R CD  1 
ATOM   1436 N  NE  . ARG A 1 341 ? 141.294 112.033 136.920 1.00 39.67  ? 220 ARG R NE  1 
ATOM   1437 C  CZ  . ARG A 1 341 ? 142.431 112.711 136.853 1.00 34.96  ? 220 ARG R CZ  1 
ATOM   1438 N  NH1 . ARG A 1 341 ? 143.426 112.319 136.075 1.00 28.66  ? 220 ARG R NH1 1 
ATOM   1439 N  NH2 . ARG A 1 341 ? 142.573 113.812 137.584 1.00 29.39  ? 220 ARG R NH2 1 
ATOM   1440 N  N   . ILE A 1 342 ? 135.566 111.333 138.396 1.00 20.33  ? 221 ILE R N   1 
ATOM   1441 C  CA  . ILE A 1 342 ? 134.750 111.911 139.452 1.00 24.37  ? 221 ILE R CA  1 
ATOM   1442 C  C   . ILE A 1 342 ? 133.561 111.021 139.783 1.00 29.88  ? 221 ILE R C   1 
ATOM   1443 O  O   . ILE A 1 342 ? 133.187 110.886 140.948 1.00 30.74  ? 221 ILE R O   1 
ATOM   1444 C  CB  . ILE A 1 342 ? 134.292 113.331 139.055 1.00 23.66  ? 221 ILE R CB  1 
ATOM   1445 C  CG1 . ILE A 1 342 ? 135.435 114.330 139.204 1.00 18.81  ? 221 ILE R CG1 1 
ATOM   1446 C  CG2 . ILE A 1 342 ? 133.105 113.774 139.880 1.00 22.98  ? 221 ILE R CG2 1 
ATOM   1447 C  CD1 . ILE A 1 342 ? 135.150 115.654 138.550 1.00 16.65  ? 221 ILE R CD1 1 
ATOM   1448 N  N   . ALA A 1 343 ? 132.964 110.395 138.769 1.00 40.84  ? 222 ALA R N   1 
ATOM   1449 C  CA  . ALA A 1 343 ? 131.850 109.489 139.007 1.00 41.28  ? 222 ALA R CA  1 
ATOM   1450 C  C   . ALA A 1 343 ? 132.296 108.184 139.649 1.00 44.32  ? 222 ALA R C   1 
ATOM   1451 O  O   . ALA A 1 343 ? 131.459 107.463 140.200 1.00 49.11  ? 222 ALA R O   1 
ATOM   1452 C  CB  . ALA A 1 343 ? 131.115 109.203 137.699 1.00 40.47  ? 222 ALA R CB  1 
ATOM   1453 N  N   . ALA A 1 344 ? 133.584 107.863 139.587 1.00 43.06  ? 223 ALA R N   1 
ATOM   1454 C  CA  . ALA A 1 344 ? 134.120 106.667 140.236 1.00 46.59  ? 223 ALA R CA  1 
ATOM   1455 C  C   . ALA A 1 344 ? 134.676 106.974 141.626 1.00 49.50  ? 223 ALA R C   1 
ATOM   1456 O  O   . ALA A 1 344 ? 135.817 106.643 141.941 1.00 51.22  ? 223 ALA R O   1 
ATOM   1457 C  CB  . ALA A 1 344 ? 135.185 106.034 139.351 1.00 44.42  ? 223 ALA R CB  1 
ATOM   1458 N  N   . LEU A 1 345 ? 133.869 107.605 142.475 1.00 47.10  ? 224 LEU R N   1 
ATOM   1459 C  CA  . LEU A 1 345 ? 134.300 107.935 143.831 1.00 46.66  ? 224 LEU R CA  1 
ATOM   1460 C  C   . LEU A 1 345 ? 133.428 107.239 144.868 1.00 45.77  ? 224 LEU R C   1 
ATOM   1461 O  O   . LEU A 1 345 ? 133.449 107.594 146.046 1.00 45.48  ? 224 LEU R O   1 
ATOM   1462 C  CB  . LEU A 1 345 ? 134.269 109.448 144.064 1.00 46.78  ? 224 LEU R CB  1 
ATOM   1463 C  CG  . LEU A 1 345 ? 135.369 110.302 143.429 1.00 45.44  ? 224 LEU R CG  1 
ATOM   1464 C  CD1 . LEU A 1 345 ? 135.083 111.777 143.650 1.00 39.85  ? 224 LEU R CD1 1 
ATOM   1465 C  CD2 . LEU A 1 345 ? 136.739 109.933 143.969 1.00 42.21  ? 224 LEU R CD2 1 
ATOM   1466 N  N   . MET A 1 359 ? 124.182 115.502 128.616 1.00 35.45  ? 238 MET R N   1 
ATOM   1467 C  CA  . MET A 1 359 ? 125.479 116.047 128.996 1.00 37.68  ? 238 MET R CA  1 
ATOM   1468 C  C   . MET A 1 359 ? 125.469 117.568 128.889 1.00 39.40  ? 238 MET R C   1 
ATOM   1469 O  O   . MET A 1 359 ? 124.728 118.137 128.095 1.00 39.05  ? 238 MET R O   1 
ATOM   1470 C  CB  . MET A 1 359 ? 126.589 115.451 128.124 1.00 37.17  ? 238 MET R CB  1 
ATOM   1471 C  CG  . MET A 1 359 ? 127.990 115.573 128.705 1.00 34.09  ? 238 MET R CG  1 
ATOM   1472 S  SD  . MET A 1 359 ? 128.350 114.341 129.969 1.00 54.82  ? 238 MET R SD  1 
ATOM   1473 C  CE  . MET A 1 359 ? 129.686 113.434 129.200 1.00 36.69  ? 238 MET R CE  1 
ATOM   1474 N  N   . LYS A 1 360 ? 126.294 118.220 129.704 1.00 32.37  ? 239 LYS R N   1 
ATOM   1475 C  CA  . LYS A 1 360 ? 126.379 119.673 129.734 1.00 27.26  ? 239 LYS R CA  1 
ATOM   1476 C  C   . LYS A 1 360 ? 127.438 120.200 128.775 1.00 30.91  ? 239 LYS R C   1 
ATOM   1477 O  O   . LYS A 1 360 ? 127.181 121.134 128.006 1.00 35.43  ? 239 LYS R O   1 
ATOM   1478 C  CB  . LYS A 1 360 ? 126.676 120.138 131.162 1.00 24.69  ? 239 LYS R CB  1 
ATOM   1479 C  CG  . LYS A 1 360 ? 127.012 121.600 131.288 1.00 27.05  ? 239 LYS R CG  1 
ATOM   1480 C  CD  . LYS A 1 360 ? 127.100 122.010 132.740 1.00 31.33  ? 239 LYS R CD  1 
ATOM   1481 C  CE  . LYS A 1 360 ? 126.354 123.308 132.977 1.00 34.61  ? 239 LYS R CE  1 
ATOM   1482 N  NZ  . LYS A 1 360 ? 126.650 123.893 134.307 1.00 34.27  ? 239 LYS R NZ  1 
ATOM   1483 N  N   . GLY A 1 361 ? 128.632 119.611 128.810 1.00 28.44  ? 240 GLY R N   1 
ATOM   1484 C  CA  . GLY A 1 361 ? 129.695 120.067 127.936 1.00 19.56  ? 240 GLY R CA  1 
ATOM   1485 C  C   . GLY A 1 361 ? 129.360 119.887 126.472 1.00 24.05  ? 240 GLY R C   1 
ATOM   1486 O  O   . GLY A 1 361 ? 129.680 120.742 125.644 1.00 32.30  ? 240 GLY R O   1 
ATOM   1487 N  N   . ALA A 1 362 ? 128.711 118.772 126.133 1.00 28.51  ? 241 ALA R N   1 
ATOM   1488 C  CA  . ALA A 1 362 ? 128.322 118.533 124.749 1.00 24.87  ? 241 ALA R CA  1 
ATOM   1489 C  C   . ALA A 1 362 ? 127.333 119.581 124.271 1.00 22.71  ? 241 ALA R C   1 
ATOM   1490 O  O   . ALA A 1 362 ? 127.438 120.072 123.145 1.00 25.56  ? 241 ALA R O   1 
ATOM   1491 C  CB  . ALA A 1 362 ? 127.730 117.134 124.603 1.00 19.67  ? 241 ALA R CB  1 
ATOM   1492 N  N   . VAL A 1 363 ? 126.370 119.943 125.118 1.00 24.04  ? 242 VAL R N   1 
ATOM   1493 C  CA  . VAL A 1 363 ? 125.390 120.961 124.748 1.00 23.77  ? 242 VAL R CA  1 
ATOM   1494 C  C   . VAL A 1 363 ? 126.065 122.313 124.559 1.00 22.26  ? 242 VAL R C   1 
ATOM   1495 O  O   . VAL A 1 363 ? 125.776 123.035 123.599 1.00 25.03  ? 242 VAL R O   1 
ATOM   1496 C  CB  . VAL A 1 363 ? 124.268 121.021 125.800 1.00 19.99  ? 242 VAL R CB  1 
ATOM   1497 C  CG1 . VAL A 1 363 ? 123.612 122.382 125.810 1.00 19.89  ? 242 VAL R CG1 1 
ATOM   1498 C  CG2 . VAL A 1 363 ? 123.246 119.942 125.530 1.00 20.42  ? 242 VAL R CG2 1 
ATOM   1499 N  N   . THR A 1 364 ? 126.975 122.679 125.463 1.00 19.55  ? 243 THR R N   1 
ATOM   1500 C  CA  . THR A 1 364 ? 127.673 123.957 125.333 1.00 19.88  ? 243 THR R CA  1 
ATOM   1501 C  C   . THR A 1 364 ? 128.501 124.010 124.051 1.00 19.17  ? 243 THR R C   1 
ATOM   1502 O  O   . THR A 1 364 ? 128.473 125.008 123.316 1.00 27.04  ? 243 THR R O   1 
ATOM   1503 C  CB  . THR A 1 364 ? 128.556 124.185 126.559 1.00 21.56  ? 243 THR R CB  1 
ATOM   1504 O  OG1 . THR A 1 364 ? 127.755 124.101 127.742 1.00 22.40  ? 243 THR R OG1 1 
ATOM   1505 C  CG2 . THR A 1 364 ? 129.215 125.543 126.502 1.00 17.36  ? 243 THR R CG2 1 
ATOM   1506 N  N   . ILE A 1 365 ? 129.241 122.936 123.764 1.00 14.79  ? 244 ILE R N   1 
ATOM   1507 C  CA  . ILE A 1 365 ? 130.063 122.873 122.558 1.00 15.39  ? 244 ILE R CA  1 
ATOM   1508 C  C   . ILE A 1 365 ? 129.190 122.933 121.312 1.00 24.59  ? 244 ILE R C   1 
ATOM   1509 O  O   . ILE A 1 365 ? 129.534 123.593 120.322 1.00 25.09  ? 244 ILE R O   1 
ATOM   1510 C  CB  . ILE A 1 365 ? 130.935 121.603 122.587 1.00 19.13  ? 244 ILE R CB  1 
ATOM   1511 C  CG1 . ILE A 1 365 ? 131.904 121.597 121.411 1.00 26.74  ? 244 ILE R CG1 1 
ATOM   1512 C  CG2 . ILE A 1 365 ? 130.095 120.355 122.571 1.00 20.52  ? 244 ILE R CG2 1 
ATOM   1513 C  CD1 . ILE A 1 365 ? 132.990 120.566 121.530 1.00 24.69  ? 244 ILE R CD1 1 
ATOM   1514 N  N   . THR A 1 366 ? 128.053 122.236 121.336 1.00 27.93  ? 245 THR R N   1 
ATOM   1515 C  CA  . THR A 1 366 ? 127.128 122.273 120.213 1.00 20.30  ? 245 THR R CA  1 
ATOM   1516 C  C   . THR A 1 366 ? 126.615 123.685 119.982 1.00 20.39  ? 245 THR R C   1 
ATOM   1517 O  O   . THR A 1 366 ? 126.604 124.168 118.850 1.00 24.68  ? 245 THR R O   1 
ATOM   1518 C  CB  . THR A 1 366 ? 125.970 121.306 120.464 1.00 22.09  ? 245 THR R CB  1 
ATOM   1519 O  OG1 . THR A 1 366 ? 126.425 119.962 120.280 1.00 30.97  ? 245 THR R OG1 1 
ATOM   1520 C  CG2 . THR A 1 366 ? 124.827 121.571 119.509 1.00 20.70  ? 245 THR R CG2 1 
ATOM   1521 N  N   . ILE A 1 367 ? 126.218 124.378 121.050 1.00 21.29  ? 246 ILE R N   1 
ATOM   1522 C  CA  . ILE A 1 367 ? 125.723 125.744 120.899 1.00 16.07  ? 246 ILE R CA  1 
ATOM   1523 C  C   . ILE A 1 367 ? 126.790 126.626 120.265 1.00 16.53  ? 246 ILE R C   1 
ATOM   1524 O  O   . ILE A 1 367 ? 126.545 127.287 119.249 1.00 30.89  ? 246 ILE R O   1 
ATOM   1525 C  CB  . ILE A 1 367 ? 125.267 126.309 122.255 1.00 23.05  ? 246 ILE R CB  1 
ATOM   1526 C  CG1 . ILE A 1 367 ? 124.070 125.530 122.802 1.00 23.03  ? 246 ILE R CG1 1 
ATOM   1527 C  CG2 . ILE A 1 367 ? 124.941 127.782 122.130 1.00 20.04  ? 246 ILE R CG2 1 
ATOM   1528 C  CD1 . ILE A 1 367 ? 122.736 126.112 122.444 1.00 23.20  ? 246 ILE R CD1 1 
ATOM   1529 N  N   . LEU A 1 368 ? 128.005 126.607 120.819 1.00 14.02  ? 247 LEU R N   1 
ATOM   1530 C  CA  . LEU A 1 368 ? 129.058 127.484 120.308 1.00 19.82  ? 247 LEU R CA  1 
ATOM   1531 C  C   . LEU A 1 368 ? 129.362 127.198 118.842 1.00 20.70  ? 247 LEU R C   1 
ATOM   1532 O  O   . LEU A 1 368 ? 129.268 128.090 117.985 1.00 22.07  ? 247 LEU R O   1 
ATOM   1533 C  CB  . LEU A 1 368 ? 130.332 127.335 121.145 1.00 17.16  ? 247 LEU R CB  1 
ATOM   1534 C  CG  . LEU A 1 368 ? 130.346 127.797 122.601 1.00 17.87  ? 247 LEU R CG  1 
ATOM   1535 C  CD1 . LEU A 1 368 ? 131.686 127.501 123.222 1.00 16.79  ? 247 LEU R CD1 1 
ATOM   1536 C  CD2 . LEU A 1 368 ? 130.046 129.266 122.694 1.00 18.39  ? 247 LEU R CD2 1 
ATOM   1537 N  N   . LEU A 1 369 ? 129.699 125.948 118.524 1.00 21.12  ? 248 LEU R N   1 
ATOM   1538 C  CA  . LEU A 1 369 ? 130.138 125.646 117.168 1.00 23.34  ? 248 LEU R CA  1 
ATOM   1539 C  C   . LEU A 1 369 ? 128.992 125.762 116.172 1.00 22.08  ? 248 LEU R C   1 
ATOM   1540 O  O   . LEU A 1 369 ? 129.177 126.292 115.074 1.00 25.81  ? 248 LEU R O   1 
ATOM   1541 C  CB  . LEU A 1 369 ? 130.774 124.259 117.119 1.00 20.80  ? 248 LEU R CB  1 
ATOM   1542 C  CG  . LEU A 1 369 ? 132.007 124.105 118.011 1.00 21.57  ? 248 LEU R CG  1 
ATOM   1543 C  CD1 . LEU A 1 369 ? 132.627 122.734 117.870 1.00 19.70  ? 248 LEU R CD1 1 
ATOM   1544 C  CD2 . LEU A 1 369 ? 133.017 125.177 117.701 1.00 20.82  ? 248 LEU R CD2 1 
ATOM   1545 N  N   . GLY A 1 370 ? 127.802 125.278 116.526 1.00 18.86  ? 249 GLY R N   1 
ATOM   1546 C  CA  . GLY A 1 370 ? 126.680 125.385 115.619 1.00 14.30  ? 249 GLY R CA  1 
ATOM   1547 C  C   . GLY A 1 370 ? 126.327 126.821 115.303 1.00 23.31  ? 249 GLY R C   1 
ATOM   1548 O  O   . GLY A 1 370 ? 126.050 127.155 114.152 1.00 30.62  ? 249 GLY R O   1 
ATOM   1549 N  N   . VAL A 1 371 ? 126.345 127.699 116.308 1.00 23.33  ? 250 VAL R N   1 
ATOM   1550 C  CA  . VAL A 1 371 ? 126.108 129.109 116.024 1.00 20.33  ? 250 VAL R CA  1 
ATOM   1551 C  C   . VAL A 1 371 ? 127.168 129.631 115.067 1.00 22.13  ? 250 VAL R C   1 
ATOM   1552 O  O   . VAL A 1 371 ? 126.852 130.286 114.068 1.00 27.05  ? 250 VAL R O   1 
ATOM   1553 C  CB  . VAL A 1 371 ? 126.060 129.921 117.328 1.00 20.23  ? 250 VAL R CB  1 
ATOM   1554 C  CG1 . VAL A 1 371 ? 126.271 131.393 117.046 1.00 25.62  ? 250 VAL R CG1 1 
ATOM   1555 C  CG2 . VAL A 1 371 ? 124.733 129.703 118.020 1.00 21.28  ? 250 VAL R CG2 1 
ATOM   1556 N  N   . PHE A 1 372 ? 128.437 129.297 115.321 1.00 23.75  ? 251 PHE R N   1 
ATOM   1557 C  CA  . PHE A 1 372 ? 129.505 129.801 114.461 1.00 23.11  ? 251 PHE R CA  1 
ATOM   1558 C  C   . PHE A 1 372 ? 129.286 129.399 113.005 1.00 24.10  ? 251 PHE R C   1 
ATOM   1559 O  O   . PHE A 1 372 ? 129.193 130.259 112.120 1.00 29.13  ? 251 PHE R O   1 
ATOM   1560 C  CB  . PHE A 1 372 ? 130.863 129.307 114.954 1.00 26.55  ? 251 PHE R CB  1 
ATOM   1561 C  CG  . PHE A 1 372 ? 132.025 129.906 114.219 1.00 29.04  ? 251 PHE R CG  1 
ATOM   1562 C  CD1 . PHE A 1 372 ? 132.561 131.114 114.620 1.00 32.50  ? 251 PHE R CD1 1 
ATOM   1563 C  CD2 . PHE A 1 372 ? 132.586 129.267 113.136 1.00 26.64  ? 251 PHE R CD2 1 
ATOM   1564 C  CE1 . PHE A 1 372 ? 133.626 131.674 113.952 1.00 28.54  ? 251 PHE R CE1 1 
ATOM   1565 C  CE2 . PHE A 1 372 ? 133.653 129.827 112.468 1.00 27.25  ? 251 PHE R CE2 1 
ATOM   1566 C  CZ  . PHE A 1 372 ? 134.172 131.029 112.879 1.00 27.79  ? 251 PHE R CZ  1 
ATOM   1567 N  N   . ILE A 1 373 ? 129.199 128.095 112.731 1.00 26.44  ? 252 ILE R N   1 
ATOM   1568 C  CA  . ILE A 1 373 ? 129.047 127.665 111.340 1.00 25.84  ? 252 ILE R CA  1 
ATOM   1569 C  C   . ILE A 1 373 ? 127.726 128.136 110.746 1.00 28.32  ? 252 ILE R C   1 
ATOM   1570 O  O   . ILE A 1 373 ? 127.712 128.727 109.665 1.00 33.86  ? 252 ILE R O   1 
ATOM   1571 C  CB  . ILE A 1 373 ? 129.251 126.146 111.150 1.00 27.46  ? 252 ILE R CB  1 
ATOM   1572 C  CG1 . ILE A 1 373 ? 130.554 125.634 111.777 1.00 28.01  ? 252 ILE R CG1 1 
ATOM   1573 C  CG2 . ILE A 1 373 ? 129.166 125.774 109.691 1.00 30.54  ? 252 ILE R CG2 1 
ATOM   1574 C  CD1 . ILE A 1 373 ? 130.440 124.830 113.004 1.00 27.88  ? 252 ILE R CD1 1 
ATOM   1575 N  N   . PHE A 1 374 ? 126.600 127.908 111.423 1.00 29.69  ? 253 PHE R N   1 
ATOM   1576 C  CA  . PHE A 1 374 ? 125.330 128.245 110.789 1.00 30.70  ? 253 PHE R CA  1 
ATOM   1577 C  C   . PHE A 1 374 ? 125.120 129.745 110.623 1.00 34.63  ? 253 PHE R C   1 
ATOM   1578 O  O   . PHE A 1 374 ? 124.221 130.143 109.878 1.00 37.33  ? 253 PHE R O   1 
ATOM   1579 C  CB  . PHE A 1 374 ? 124.165 127.633 111.564 1.00 31.08  ? 253 PHE R CB  1 
ATOM   1580 C  CG  . PHE A 1 374 ? 124.122 126.134 111.497 1.00 39.13  ? 253 PHE R CG  1 
ATOM   1581 C  CD1 . PHE A 1 374 ? 124.074 125.491 110.274 1.00 33.26  ? 253 PHE R CD1 1 
ATOM   1582 C  CD2 . PHE A 1 374 ? 124.103 125.369 112.648 1.00 34.02  ? 253 PHE R CD2 1 
ATOM   1583 C  CE1 . PHE A 1 374 ? 124.033 124.118 110.199 1.00 34.93  ? 253 PHE R CE1 1 
ATOM   1584 C  CE2 . PHE A 1 374 ? 124.059 123.993 112.578 1.00 31.96  ? 253 PHE R CE2 1 
ATOM   1585 C  CZ  . PHE A 1 374 ? 124.023 123.369 111.352 1.00 36.11  ? 253 PHE R CZ  1 
ATOM   1586 N  N   . CYS A 1 375 ? 125.921 130.589 111.273 1.00 34.19  ? 254 CYS R N   1 
ATOM   1587 C  CA  . CYS A 1 375 ? 125.817 132.020 111.027 1.00 25.18  ? 254 CYS R CA  1 
ATOM   1588 C  C   . CYS A 1 375 ? 126.861 132.552 110.058 1.00 32.54  ? 254 CYS R C   1 
ATOM   1589 O  O   . CYS A 1 375 ? 126.595 133.546 109.380 1.00 42.04  ? 254 CYS R O   1 
ATOM   1590 C  CB  . CYS A 1 375 ? 125.914 132.794 112.342 1.00 29.09  ? 254 CYS R CB  1 
ATOM   1591 S  SG  . CYS A 1 375 ? 124.404 132.757 113.323 1.00 45.63  ? 254 CYS R SG  1 
ATOM   1592 N  N   . TRP A 1 376 ? 128.034 131.927 109.950 1.00 36.72  ? 255 TRP R N   1 
ATOM   1593 C  CA  . TRP A 1 376 ? 129.065 132.463 109.068 1.00 30.54  ? 255 TRP R CA  1 
ATOM   1594 C  C   . TRP A 1 376 ? 129.233 131.699 107.762 1.00 34.17  ? 255 TRP R C   1 
ATOM   1595 O  O   . TRP A 1 376 ? 129.555 132.316 106.745 1.00 34.63  ? 255 TRP R O   1 
ATOM   1596 C  CB  . TRP A 1 376 ? 130.412 132.503 109.795 1.00 30.38  ? 255 TRP R CB  1 
ATOM   1597 C  CG  . TRP A 1 376 ? 130.472 133.519 110.893 1.00 36.82  ? 255 TRP R CG  1 
ATOM   1598 C  CD1 . TRP A 1 376 ? 130.340 133.287 112.226 1.00 34.61  ? 255 TRP R CD1 1 
ATOM   1599 C  CD2 . TRP A 1 376 ? 130.692 134.925 110.753 1.00 37.61  ? 255 TRP R CD2 1 
ATOM   1600 N  NE1 . TRP A 1 376 ? 130.455 134.458 112.925 1.00 34.52  ? 255 TRP R NE1 1 
ATOM   1601 C  CE2 . TRP A 1 376 ? 130.673 135.480 112.042 1.00 33.96  ? 255 TRP R CE2 1 
ATOM   1602 C  CE3 . TRP A 1 376 ? 130.899 135.769 109.661 1.00 33.75  ? 255 TRP R CE3 1 
ATOM   1603 C  CZ2 . TRP A 1 376 ? 130.852 136.837 112.271 1.00 32.25  ? 255 TRP R CZ2 1 
ATOM   1604 C  CZ3 . TRP A 1 376 ? 131.076 137.112 109.891 1.00 33.89  ? 255 TRP R CZ3 1 
ATOM   1605 C  CH2 . TRP A 1 376 ? 131.051 137.635 111.185 1.00 32.99  ? 255 TRP R CH2 1 
ATOM   1606 N  N   . ALA A 1 377 ? 129.036 130.382 107.758 1.00 39.03  ? 256 ALA R N   1 
ATOM   1607 C  CA  . ALA A 1 377 ? 129.345 129.574 106.581 1.00 37.58  ? 256 ALA R CA  1 
ATOM   1608 C  C   . ALA A 1 377 ? 128.505 129.867 105.342 1.00 42.97  ? 256 ALA R C   1 
ATOM   1609 O  O   . ALA A 1 377 ? 129.053 129.748 104.234 1.00 45.56  ? 256 ALA R O   1 
ATOM   1610 C  CB  . ALA A 1 377 ? 129.243 128.089 106.941 1.00 33.56  ? 256 ALA R CB  1 
ATOM   1611 N  N   . PRO A 1 378 ? 127.199 130.159 105.421 1.00 42.63  ? 257 PRO R N   1 
ATOM   1612 C  CA  . PRO A 1 378 ? 126.458 130.425 104.174 1.00 43.37  ? 257 PRO R CA  1 
ATOM   1613 C  C   . PRO A 1 378 ? 127.045 131.541 103.322 1.00 48.49  ? 257 PRO R C   1 
ATOM   1614 O  O   . PRO A 1 378 ? 127.113 131.400 102.094 1.00 54.59  ? 257 PRO R O   1 
ATOM   1615 C  CB  . PRO A 1 378 ? 125.056 130.774 104.681 1.00 43.42  ? 257 PRO R CB  1 
ATOM   1616 C  CG  . PRO A 1 378 ? 124.933 130.037 105.936 1.00 41.48  ? 257 PRO R CG  1 
ATOM   1617 C  CD  . PRO A 1 378 ? 126.284 130.052 106.570 1.00 39.78  ? 257 PRO R CD  1 
ATOM   1618 N  N   . PHE A 1 379 ? 127.496 132.638 103.936 1.00 44.64  ? 258 PHE R N   1 
ATOM   1619 C  CA  . PHE A 1 379 ? 128.066 133.736 103.162 1.00 40.17  ? 258 PHE R CA  1 
ATOM   1620 C  C   . PHE A 1 379 ? 129.337 133.306 102.433 1.00 42.96  ? 258 PHE R C   1 
ATOM   1621 O  O   . PHE A 1 379 ? 129.520 133.610 101.247 1.00 44.80  ? 258 PHE R O   1 
ATOM   1622 C  CB  . PHE A 1 379 ? 128.343 134.926 104.081 1.00 44.75  ? 258 PHE R CB  1 
ATOM   1623 C  CG  . PHE A 1 379 ? 129.049 136.064 103.406 1.00 44.70  ? 258 PHE R CG  1 
ATOM   1624 C  CD1 . PHE A 1 379 ? 128.383 136.871 102.507 1.00 47.63  ? 258 PHE R CD1 1 
ATOM   1625 C  CD2 . PHE A 1 379 ? 130.376 136.327 103.670 1.00 43.47  ? 258 PHE R CD2 1 
ATOM   1626 C  CE1 . PHE A 1 379 ? 129.027 137.907 101.885 1.00 45.68  ? 258 PHE R CE1 1 
ATOM   1627 C  CE2 . PHE A 1 379 ? 131.024 137.361 103.048 1.00 42.68  ? 258 PHE R CE2 1 
ATOM   1628 C  CZ  . PHE A 1 379 ? 130.347 138.152 102.156 1.00 47.92  ? 258 PHE R CZ  1 
ATOM   1629 N  N   . PHE A 1 380 ? 130.221 132.581 103.114 1.00 40.23  ? 259 PHE R N   1 
ATOM   1630 C  CA  . PHE A 1 380 ? 131.465 132.160 102.488 1.00 39.59  ? 259 PHE R CA  1 
ATOM   1631 C  C   . PHE A 1 380 ? 131.262 131.032 101.490 1.00 42.36  ? 259 PHE R C   1 
ATOM   1632 O  O   . PHE A 1 380 ? 132.040 130.913 100.541 1.00 48.77  ? 259 PHE R O   1 
ATOM   1633 C  CB  . PHE A 1 380 ? 132.477 131.763 103.558 1.00 35.73  ? 259 PHE R CB  1 
ATOM   1634 C  CG  . PHE A 1 380 ? 132.935 132.915 104.398 1.00 37.10  ? 259 PHE R CG  1 
ATOM   1635 C  CD1 . PHE A 1 380 ? 132.170 133.367 105.452 1.00 37.19  ? 259 PHE R CD1 1 
ATOM   1636 C  CD2 . PHE A 1 380 ? 134.118 133.565 104.117 1.00 36.64  ? 259 PHE R CD2 1 
ATOM   1637 C  CE1 . PHE A 1 380 ? 132.583 134.429 106.218 1.00 37.87  ? 259 PHE R CE1 1 
ATOM   1638 C  CE2 . PHE A 1 380 ? 134.531 134.628 104.879 1.00 37.58  ? 259 PHE R CE2 1 
ATOM   1639 C  CZ  . PHE A 1 380 ? 133.763 135.059 105.931 1.00 38.10  ? 259 PHE R CZ  1 
ATOM   1640 N  N   . LEU A 1 381 ? 130.218 130.225 101.655 1.00 46.33  ? 260 LEU R N   1 
ATOM   1641 C  CA  . LEU A 1 381 ? 129.849 129.279 100.612 1.00 50.44  ? 260 LEU R CA  1 
ATOM   1642 C  C   . LEU A 1 381 ? 129.326 129.994 99.375  1.00 52.73  ? 260 LEU R C   1 
ATOM   1643 O  O   . LEU A 1 381 ? 129.589 129.557 98.252  1.00 52.59  ? 260 LEU R O   1 
ATOM   1644 C  CB  . LEU A 1 381 ? 128.807 128.296 101.139 1.00 51.57  ? 260 LEU R CB  1 
ATOM   1645 C  CG  . LEU A 1 381 ? 129.209 126.825 101.149 1.00 53.76  ? 260 LEU R CG  1 
ATOM   1646 C  CD1 . LEU A 1 381 ? 128.058 125.984 101.649 1.00 53.19  ? 260 LEU R CD1 1 
ATOM   1647 C  CD2 . LEU A 1 381 ? 129.636 126.382 99.761  1.00 51.95  ? 260 LEU R CD2 1 
ATOM   1648 N  N   . HIS A 1 382 ? 128.599 131.096 99.561  1.00 57.54  ? 261 HIS R N   1 
ATOM   1649 C  CA  . HIS A 1 382 ? 128.231 131.940 98.429  1.00 53.82  ? 261 HIS R CA  1 
ATOM   1650 C  C   . HIS A 1 382 ? 129.474 132.485 97.737  1.00 53.69  ? 261 HIS R C   1 
ATOM   1651 O  O   . HIS A 1 382 ? 129.555 132.517 96.502  1.00 59.65  ? 261 HIS R O   1 
ATOM   1652 C  CB  . HIS A 1 382 ? 127.327 133.074 98.912  1.00 52.52  ? 261 HIS R CB  1 
ATOM   1653 C  CG  . HIS A 1 382 ? 127.219 134.222 97.958  1.00 57.73  ? 261 HIS R CG  1 
ATOM   1654 N  ND1 . HIS A 1 382 ? 126.201 134.329 97.037  1.00 59.61  ? 261 HIS R ND1 1 
ATOM   1655 C  CD2 . HIS A 1 382 ? 127.987 135.325 97.799  1.00 56.18  ? 261 HIS R CD2 1 
ATOM   1656 C  CE1 . HIS A 1 382 ? 126.354 135.440 96.342  1.00 56.19  ? 261 HIS R CE1 1 
ATOM   1657 N  NE2 . HIS A 1 382 ? 127.431 136.062 96.784  1.00 54.27  ? 261 HIS R NE2 1 
ATOM   1658 N  N   . LEU A 1 383 ? 130.454 132.924 98.527  1.00 53.49  ? 262 LEU R N   1 
ATOM   1659 C  CA  . LEU A 1 383 ? 131.700 133.434 97.958  1.00 54.20  ? 262 LEU R CA  1 
ATOM   1660 C  C   . LEU A 1 383 ? 132.428 132.357 97.161  1.00 56.20  ? 262 LEU R C   1 
ATOM   1661 O  O   . LEU A 1 383 ? 133.024 132.643 96.117  1.00 57.35  ? 262 LEU R O   1 
ATOM   1662 C  CB  . LEU A 1 383 ? 132.601 133.974 99.067  1.00 53.41  ? 262 LEU R CB  1 
ATOM   1663 C  CG  . LEU A 1 383 ? 132.551 135.477 99.318  1.00 52.40  ? 262 LEU R CG  1 
ATOM   1664 C  CD1 . LEU A 1 383 ? 133.450 135.843 100.474 1.00 52.80  ? 262 LEU R CD1 1 
ATOM   1665 C  CD2 . LEU A 1 383 ? 132.957 136.219 98.072  1.00 54.51  ? 262 LEU R CD2 1 
ATOM   1666 N  N   . VAL A 1 384 ? 132.416 131.119 97.654  1.00 61.42  ? 263 VAL R N   1 
ATOM   1667 C  CA  . VAL A 1 384 ? 133.002 130.011 96.903  1.00 61.02  ? 263 VAL R CA  1 
ATOM   1668 C  C   . VAL A 1 384 ? 132.234 129.775 95.608  1.00 62.53  ? 263 VAL R C   1 
ATOM   1669 O  O   . VAL A 1 384 ? 132.830 129.575 94.542  1.00 65.19  ? 263 VAL R O   1 
ATOM   1670 C  CB  . VAL A 1 384 ? 133.041 128.739 97.769  1.00 59.75  ? 263 VAL R CB  1 
ATOM   1671 C  CG1 . VAL A 1 384 ? 133.419 127.538 96.927  1.00 58.51  ? 263 VAL R CG1 1 
ATOM   1672 C  CG2 . VAL A 1 384 ? 134.007 128.906 98.920  1.00 61.63  ? 263 VAL R CG2 1 
ATOM   1673 N  N   . LEU A 1 385 ? 130.901 129.792 95.679  1.00 65.60  ? 264 LEU R N   1 
ATOM   1674 C  CA  . LEU A 1 385 ? 130.079 129.444 94.526  1.00 65.86  ? 264 LEU R CA  1 
ATOM   1675 C  C   . LEU A 1 385 ? 130.178 130.462 93.400  1.00 64.68  ? 264 LEU R C   1 
ATOM   1676 O  O   . LEU A 1 385 ? 130.162 130.069 92.231  1.00 67.30  ? 264 LEU R O   1 
ATOM   1677 C  CB  . LEU A 1 385 ? 128.619 129.282 94.951  1.00 66.74  ? 264 LEU R CB  1 
ATOM   1678 C  CG  . LEU A 1 385 ? 128.248 127.906 95.503  1.00 67.50  ? 264 LEU R CG  1 
ATOM   1679 C  CD1 . LEU A 1 385 ? 126.744 127.745 95.591  1.00 67.55  ? 264 LEU R CD1 1 
ATOM   1680 C  CD2 . LEU A 1 385 ? 128.856 126.809 94.652  1.00 66.24  ? 264 LEU R CD2 1 
ATOM   1681 N  N   . ILE A 1 386 ? 130.275 131.758 93.711  1.00 62.82  ? 265 ILE R N   1 
ATOM   1682 C  CA  . ILE A 1 386 ? 130.344 132.751 92.638  1.00 62.74  ? 265 ILE R CA  1 
ATOM   1683 C  C   . ILE A 1 386 ? 131.675 132.761 91.897  1.00 66.45  ? 265 ILE R C   1 
ATOM   1684 O  O   . ILE A 1 386 ? 131.783 133.434 90.860  1.00 68.47  ? 265 ILE R O   1 
ATOM   1685 C  CB  . ILE A 1 386 ? 130.052 134.187 93.124  1.00 62.80  ? 265 ILE R CB  1 
ATOM   1686 C  CG1 . ILE A 1 386 ? 131.297 134.825 93.733  1.00 62.58  ? 265 ILE R CG1 1 
ATOM   1687 C  CG2 . ILE A 1 386 ? 128.866 134.225 94.060  1.00 64.24  ? 265 ILE R CG2 1 
ATOM   1688 C  CD1 . ILE A 1 386 ? 131.057 136.202 94.272  1.00 63.66  ? 265 ILE R CD1 1 
ATOM   1689 N  N   . ILE A 1 387 ? 132.690 132.043 92.375  1.00 70.65  ? 266 ILE R N   1 
ATOM   1690 C  CA  . ILE A 1 387 ? 133.967 131.962 91.672  1.00 68.86  ? 266 ILE R CA  1 
ATOM   1691 C  C   . ILE A 1 387 ? 134.312 130.556 91.209  1.00 69.38  ? 266 ILE R C   1 
ATOM   1692 O  O   . ILE A 1 387 ? 135.215 130.407 90.373  1.00 69.71  ? 266 ILE R O   1 
ATOM   1693 C  CB  . ILE A 1 387 ? 135.129 132.528 92.517  1.00 66.65  ? 266 ILE R CB  1 
ATOM   1694 C  CG1 . ILE A 1 387 ? 135.690 131.454 93.446  1.00 68.53  ? 266 ILE R CG1 1 
ATOM   1695 C  CG2 . ILE A 1 387 ? 134.683 133.737 93.299  1.00 66.72  ? 266 ILE R CG2 1 
ATOM   1696 C  CD1 . ILE A 1 387 ? 137.072 131.754 93.955  1.00 67.48  ? 266 ILE R CD1 1 
ATOM   1697 N  N   . THR A 1 388 ? 133.648 129.517 91.716  1.00 75.33  ? 267 THR R N   1 
ATOM   1698 C  CA  . THR A 1 388 ? 133.939 128.173 91.227  1.00 75.39  ? 267 THR R CA  1 
ATOM   1699 C  C   . THR A 1 388 ? 133.120 127.817 89.993  1.00 76.15  ? 267 THR R C   1 
ATOM   1700 O  O   . THR A 1 388 ? 133.645 127.200 89.060  1.00 76.98  ? 267 THR R O   1 
ATOM   1701 C  CB  . THR A 1 388 ? 133.694 127.136 92.326  1.00 74.21  ? 267 THR R CB  1 
ATOM   1702 O  OG1 . THR A 1 388 ? 132.393 127.331 92.890  1.00 72.67  ? 267 THR R OG1 1 
ATOM   1703 C  CG2 . THR A 1 388 ? 134.744 127.257 93.415  1.00 74.15  ? 267 THR R CG2 1 
ATOM   1704 N  N   . CYS A 1 389 ? 131.845 128.190 89.970  1.00 84.81  ? 268 CYS R N   1 
ATOM   1705 C  CA  . CYS A 1 389 ? 130.979 127.933 88.829  1.00 85.52  ? 268 CYS R CA  1 
ATOM   1706 C  C   . CYS A 1 389 ? 129.785 128.878 88.865  1.00 87.19  ? 268 CYS R C   1 
ATOM   1707 O  O   . CYS A 1 389 ? 128.720 128.518 89.381  1.00 86.55  ? 268 CYS R O   1 
ATOM   1708 C  CB  . CYS A 1 389 ? 130.518 126.476 88.822  1.00 86.53  ? 268 CYS R CB  1 
ATOM   1709 S  SG  . CYS A 1 389 ? 130.213 125.797 90.461  1.00 93.40  ? 268 CYS R SG  1 
ATOM   1710 N  N   . PRO A 1 390 ? 129.922 130.090 88.325  1.00 88.07  ? 269 PRO R N   1 
ATOM   1711 C  CA  . PRO A 1 390 ? 128.854 131.088 88.425  1.00 86.69  ? 269 PRO R CA  1 
ATOM   1712 C  C   . PRO A 1 390 ? 127.751 130.950 87.389  1.00 88.20  ? 269 PRO R C   1 
ATOM   1713 O  O   . PRO A 1 390 ? 126.892 131.832 87.313  1.00 87.35  ? 269 PRO R O   1 
ATOM   1714 C  CB  . PRO A 1 390 ? 129.609 132.416 88.225  1.00 86.49  ? 269 PRO R CB  1 
ATOM   1715 C  CG  . PRO A 1 390 ? 131.063 132.051 87.967  1.00 86.90  ? 269 PRO R CG  1 
ATOM   1716 C  CD  . PRO A 1 390 ? 131.090 130.612 87.605  1.00 86.24  ? 269 PRO R CD  1 
ATOM   1717 N  N   . THR A 1 391 ? 127.743 129.885 86.590  1.00 99.60  ? 270 THR R N   1 
ATOM   1718 C  CA  . THR A 1 391 ? 126.781 129.748 85.508  1.00 99.07  ? 270 THR R CA  1 
ATOM   1719 C  C   . THR A 1 391 ? 125.899 128.511 85.608  1.00 98.73  ? 270 THR R C   1 
ATOM   1720 O  O   . THR A 1 391 ? 124.971 128.377 84.802  1.00 99.22  ? 270 THR R O   1 
ATOM   1721 C  CB  . THR A 1 391 ? 127.503 129.734 84.152  1.00 98.28  ? 270 THR R CB  1 
ATOM   1722 O  OG1 . THR A 1 391 ? 128.632 128.854 84.218  1.00 96.96  ? 270 THR R OG1 1 
ATOM   1723 C  CG2 . THR A 1 391 ? 127.980 131.131 83.792  1.00 97.25  ? 270 THR R CG2 1 
ATOM   1724 N  N   . ASN A 1 392 ? 126.152 127.612 86.552  1.00 105.33 ? 271 ASN R N   1 
ATOM   1725 C  CA  . ASN A 1 392 ? 125.298 126.444 86.697  1.00 107.02 ? 271 ASN R CA  1 
ATOM   1726 C  C   . ASN A 1 392 ? 123.905 126.872 87.154  1.00 107.27 ? 271 ASN R C   1 
ATOM   1727 O  O   . ASN A 1 392 ? 123.777 127.766 87.998  1.00 107.74 ? 271 ASN R O   1 
ATOM   1728 C  CB  . ASN A 1 392 ? 125.895 125.454 87.698  1.00 106.02 ? 271 ASN R CB  1 
ATOM   1729 C  CG  . ASN A 1 392 ? 127.027 124.640 87.108  1.00 105.77 ? 271 ASN R CG  1 
ATOM   1730 O  OD1 . ASN A 1 392 ? 127.765 125.116 86.246  1.00 105.81 ? 271 ASN R OD1 1 
ATOM   1731 N  ND2 . ASN A 1 392 ? 127.171 123.405 87.571  1.00 105.27 ? 271 ASN R ND2 1 
ATOM   1732 N  N   . PRO A 1 393 ? 122.845 126.269 86.613  1.00 112.08 ? 272 PRO R N   1 
ATOM   1733 C  CA  . PRO A 1 393 ? 121.489 126.650 87.042  1.00 112.20 ? 272 PRO R CA  1 
ATOM   1734 C  C   . PRO A 1 393 ? 121.234 126.439 88.523  1.00 111.45 ? 272 PRO R C   1 
ATOM   1735 O  O   . PRO A 1 393 ? 120.411 127.154 89.107  1.00 110.49 ? 272 PRO R O   1 
ATOM   1736 C  CB  . PRO A 1 393 ? 120.586 125.754 86.182  1.00 111.82 ? 272 PRO R CB  1 
ATOM   1737 C  CG  . PRO A 1 393 ? 121.419 125.399 85.000  1.00 111.83 ? 272 PRO R CG  1 
ATOM   1738 C  CD  . PRO A 1 393 ? 122.829 125.309 85.498  1.00 110.87 ? 272 PRO R CD  1 
ATOM   1739 N  N   . TYR A 1 394 ? 121.900 125.472 89.148  1.00 107.72 ? 273 TYR R N   1 
ATOM   1740 C  CA  . TYR A 1 394 ? 121.744 125.244 90.577  1.00 107.45 ? 273 TYR R CA  1 
ATOM   1741 C  C   . TYR A 1 394 ? 122.720 126.054 91.418  1.00 106.87 ? 273 TYR R C   1 
ATOM   1742 O  O   . TYR A 1 394 ? 122.552 126.120 92.640  1.00 107.88 ? 273 TYR R O   1 
ATOM   1743 C  CB  . TYR A 1 394 ? 121.901 123.753 90.895  1.00 107.79 ? 273 TYR R CB  1 
ATOM   1744 C  CG  . TYR A 1 394 ? 120.789 122.901 90.329  1.00 108.59 ? 273 TYR R CG  1 
ATOM   1745 C  CD1 . TYR A 1 394 ? 119.465 123.147 90.662  1.00 109.06 ? 273 TYR R CD1 1 
ATOM   1746 C  CD2 . TYR A 1 394 ? 121.062 121.861 89.453  1.00 108.62 ? 273 TYR R CD2 1 
ATOM   1747 C  CE1 . TYR A 1 394 ? 118.445 122.378 90.146  1.00 109.02 ? 273 TYR R CE1 1 
ATOM   1748 C  CE2 . TYR A 1 394 ? 120.048 121.086 88.931  1.00 109.76 ? 273 TYR R CE2 1 
ATOM   1749 C  CZ  . TYR A 1 394 ? 118.742 121.348 89.281  1.00 110.17 ? 273 TYR R CZ  1 
ATOM   1750 O  OH  . TYR A 1 394 ? 117.726 120.578 88.764  1.00 108.61 ? 273 TYR R OH  1 
ATOM   1751 N  N   . CYS A 1 395 ? 123.725 126.670 90.802  1.00 98.62  ? 274 CYS R N   1 
ATOM   1752 C  CA  . CYS A 1 395 ? 124.626 127.572 91.505  1.00 98.46  ? 274 CYS R CA  1 
ATOM   1753 C  C   . CYS A 1 395 ? 124.154 129.017 91.467  1.00 98.30  ? 274 CYS R C   1 
ATOM   1754 O  O   . CYS A 1 395 ? 124.801 129.879 92.066  1.00 99.67  ? 274 CYS R O   1 
ATOM   1755 C  CB  . CYS A 1 395 ? 126.039 127.476 90.925  1.00 97.79  ? 274 CYS R CB  1 
ATOM   1756 S  SG  . CYS A 1 395 ? 126.936 125.993 91.408  1.00 96.75  ? 274 CYS R SG  1 
ATOM   1757 N  N   . ILE A 1 396 ? 123.057 129.303 90.769  1.00 96.71  ? 275 ILE R N   1 
ATOM   1758 C  CA  . ILE A 1 396 ? 122.428 130.615 90.845  1.00 96.48  ? 275 ILE R CA  1 
ATOM   1759 C  C   . ILE A 1 396 ? 121.214 130.606 91.769  1.00 95.91  ? 275 ILE R C   1 
ATOM   1760 O  O   . ILE A 1 396 ? 120.765 131.682 92.192  1.00 95.27  ? 275 ILE R O   1 
ATOM   1761 C  CB  . ILE A 1 396 ? 122.067 131.137 89.432  1.00 96.62  ? 275 ILE R CB  1 
ATOM   1762 C  CG1 . ILE A 1 396 ? 120.825 130.455 88.830  1.00 98.17  ? 275 ILE R CG1 1 
ATOM   1763 C  CG2 . ILE A 1 396 ? 123.253 130.985 88.496  1.00 95.01  ? 275 ILE R CG2 1 
ATOM   1764 C  CD1 . ILE A 1 396 ? 119.466 131.043 89.221  1.00 96.70  ? 275 ILE R CD1 1 
ATOM   1765 N  N   . CYS A 1 397 ? 120.671 129.432 92.091  1.00 87.27  ? 276 CYS R N   1 
ATOM   1766 C  CA  . CYS A 1 397 ? 119.595 129.341 93.067  1.00 87.03  ? 276 CYS R CA  1 
ATOM   1767 C  C   . CYS A 1 397 ? 120.101 129.478 94.495  1.00 86.94  ? 276 CYS R C   1 
ATOM   1768 O  O   . CYS A 1 397 ? 119.304 129.758 95.397  1.00 85.49  ? 276 CYS R O   1 
ATOM   1769 C  CB  . CYS A 1 397 ? 118.847 128.017 92.905  1.00 87.49  ? 276 CYS R CB  1 
ATOM   1770 S  SG  . CYS A 1 397 ? 117.430 127.824 94.008  1.00 88.33  ? 276 CYS R SG  1 
ATOM   1771 N  N   . TYR A 1 398 ? 121.398 129.277 94.721  1.00 73.00  ? 277 TYR R N   1 
ATOM   1772 C  CA  . TYR A 1 398 ? 121.991 129.553 96.021  1.00 69.70  ? 277 TYR R CA  1 
ATOM   1773 C  C   . TYR A 1 398 ? 122.431 131.006 96.134  1.00 71.65  ? 277 TYR R C   1 
ATOM   1774 O  O   . TYR A 1 398 ? 122.116 131.677 97.120  1.00 71.66  ? 277 TYR R O   1 
ATOM   1775 C  CB  . TYR A 1 398 ? 123.183 128.629 96.277  1.00 68.49  ? 277 TYR R CB  1 
ATOM   1776 C  CG  . TYR A 1 398 ? 123.771 128.805 97.655  1.00 66.82  ? 277 TYR R CG  1 
ATOM   1777 C  CD1 . TYR A 1 398 ? 123.258 128.115 98.739  1.00 68.01  ? 277 TYR R CD1 1 
ATOM   1778 C  CD2 . TYR A 1 398 ? 124.824 129.674 97.876  1.00 67.72  ? 277 TYR R CD2 1 
ATOM   1779 C  CE1 . TYR A 1 398 ? 123.785 128.277 99.996  1.00 67.54  ? 277 TYR R CE1 1 
ATOM   1780 C  CE2 . TYR A 1 398 ? 125.354 129.843 99.131  1.00 67.77  ? 277 TYR R CE2 1 
ATOM   1781 C  CZ  . TYR A 1 398 ? 124.833 129.141 100.185 1.00 66.59  ? 277 TYR R CZ  1 
ATOM   1782 O  OH  . TYR A 1 398 ? 125.362 129.304 101.439 1.00 65.50  ? 277 TYR R OH  1 
ATOM   1783 N  N   . THR A 1 399 ? 123.154 131.506 95.134  1.00 77.47  ? 278 THR R N   1 
ATOM   1784 C  CA  . THR A 1 399 ? 123.599 132.891 95.150  1.00 72.96  ? 278 THR R CA  1 
ATOM   1785 C  C   . THR A 1 399 ? 122.480 133.802 94.674  1.00 73.74  ? 278 THR R C   1 
ATOM   1786 O  O   . THR A 1 399 ? 122.685 134.649 93.801  1.00 76.13  ? 278 THR R O   1 
ATOM   1787 C  CB  . THR A 1 399 ? 124.836 133.077 94.273  1.00 73.10  ? 278 THR R CB  1 
ATOM   1788 O  OG1 . THR A 1 399 ? 124.433 133.261 92.912  1.00 76.37  ? 278 THR R OG1 1 
ATOM   1789 C  CG2 . THR A 1 399 ? 125.741 131.865 94.362  1.00 73.00  ? 278 THR R CG2 1 
ATOM   1790 N  N   . ALA A 1 400 ? 121.292 133.625 95.243  1.00 75.84  ? 279 ALA R N   1 
ATOM   1791 C  CA  . ALA A 1 400 ? 120.183 134.543 95.052  1.00 76.34  ? 279 ALA R CA  1 
ATOM   1792 C  C   . ALA A 1 400 ? 119.602 135.023 96.368  1.00 75.74  ? 279 ALA R C   1 
ATOM   1793 O  O   . ALA A 1 400 ? 118.830 135.987 96.367  1.00 76.03  ? 279 ALA R O   1 
ATOM   1794 C  CB  . ALA A 1 400 ? 119.072 133.891 94.217  1.00 75.32  ? 279 ALA R CB  1 
ATOM   1795 N  N   . HIS A 1 401 ? 119.948 134.386 97.482  1.00 68.18  ? 280 HIS R N   1 
ATOM   1796 C  CA  . HIS A 1 401 ? 119.568 134.826 98.819  1.00 68.35  ? 280 HIS R CA  1 
ATOM   1797 C  C   . HIS A 1 401 ? 120.716 135.540 99.513  1.00 66.30  ? 280 HIS R C   1 
ATOM   1798 O  O   . HIS A 1 401 ? 120.890 135.408 100.724 1.00 70.41  ? 280 HIS R O   1 
ATOM   1799 C  CB  . HIS A 1 401 ? 119.099 133.640 99.653  1.00 67.33  ? 280 HIS R CB  1 
ATOM   1800 C  CG  . HIS A 1 401 ? 118.003 132.847 99.015  1.00 67.87  ? 280 HIS R CG  1 
ATOM   1801 N  ND1 . HIS A 1 401 ? 116.677 133.213 99.093  1.00 68.05  ? 280 HIS R ND1 1 
ATOM   1802 C  CD2 . HIS A 1 401 ? 118.036 131.703 98.292  1.00 68.00  ? 280 HIS R CD2 1 
ATOM   1803 C  CE1 . HIS A 1 401 ? 115.941 132.331 98.442  1.00 68.60  ? 280 HIS R CE1 1 
ATOM   1804 N  NE2 . HIS A 1 401 ? 116.741 131.405 97.947  1.00 70.25  ? 280 HIS R NE2 1 
ATOM   1805 N  N   . PHE A 1 402 ? 121.519 136.295 98.759  1.00 59.69  ? 281 PHE R N   1 
ATOM   1806 C  CA  . PHE A 1 402 ? 122.680 136.971 99.332  1.00 58.57  ? 281 PHE R CA  1 
ATOM   1807 C  C   . PHE A 1 402 ? 122.285 137.854 100.509 1.00 60.62  ? 281 PHE R C   1 
ATOM   1808 O  O   . PHE A 1 402 ? 123.013 137.942 101.507 1.00 60.56  ? 281 PHE R O   1 
ATOM   1809 C  CB  . PHE A 1 402 ? 123.375 137.789 98.245  1.00 59.39  ? 281 PHE R CB  1 
ATOM   1810 C  CG  . PHE A 1 402 ? 124.462 138.686 98.754  1.00 60.35  ? 281 PHE R CG  1 
ATOM   1811 C  CD1 . PHE A 1 402 ? 125.665 138.162 99.184  1.00 60.00  ? 281 PHE R CD1 1 
ATOM   1812 C  CD2 . PHE A 1 402 ? 124.289 140.055 98.784  1.00 59.35  ? 281 PHE R CD2 1 
ATOM   1813 C  CE1 . PHE A 1 402 ? 126.665 138.985 99.643  1.00 59.40  ? 281 PHE R CE1 1 
ATOM   1814 C  CE2 . PHE A 1 402 ? 125.286 140.878 99.244  1.00 58.43  ? 281 PHE R CE2 1 
ATOM   1815 C  CZ  . PHE A 1 402 ? 126.475 140.342 99.674  1.00 59.01  ? 281 PHE R CZ  1 
ATOM   1816 N  N   . ASN A 1 403 ? 121.127 138.505 100.420 1.00 59.86  ? 282 ASN R N   1 
ATOM   1817 C  CA  . ASN A 1 403 ? 120.677 139.354 101.515 1.00 60.65  ? 282 ASN R CA  1 
ATOM   1818 C  C   . ASN A 1 403 ? 120.323 138.530 102.746 1.00 58.87  ? 282 ASN R C   1 
ATOM   1819 O  O   . ASN A 1 403 ? 120.586 138.951 103.878 1.00 64.46  ? 282 ASN R O   1 
ATOM   1820 C  CB  . ASN A 1 403 ? 119.490 140.196 101.061 1.00 63.51  ? 282 ASN R CB  1 
ATOM   1821 C  CG  . ASN A 1 403 ? 119.903 141.347 100.179 1.00 61.53  ? 282 ASN R CG  1 
ATOM   1822 O  OD1 . ASN A 1 403 ? 119.529 141.414 99.013  1.00 63.13  ? 282 ASN R OD1 1 
ATOM   1823 N  ND2 . ASN A 1 403 ? 120.682 142.261 100.732 1.00 60.13  ? 282 ASN R ND2 1 
ATOM   1824 N  N   . THR A 1 404 ? 119.731 137.355 102.551 1.00 54.37  ? 283 THR R N   1 
ATOM   1825 C  CA  . THR A 1 404 ? 119.456 136.462 103.668 1.00 59.49  ? 283 THR R CA  1 
ATOM   1826 C  C   . THR A 1 404 ? 120.725 136.000 104.372 1.00 59.00  ? 283 THR R C   1 
ATOM   1827 O  O   . THR A 1 404 ? 120.688 135.743 105.578 1.00 57.60  ? 283 THR R O   1 
ATOM   1828 C  CB  . THR A 1 404 ? 118.661 135.247 103.188 1.00 59.52  ? 283 THR R CB  1 
ATOM   1829 O  OG1 . THR A 1 404 ? 117.533 135.689 102.426 1.00 60.21  ? 283 THR R OG1 1 
ATOM   1830 C  CG2 . THR A 1 404 ? 118.165 134.437 104.370 1.00 55.99  ? 283 THR R CG2 1 
ATOM   1831 N  N   . TYR A 1 405 ? 121.840 135.901 103.653 1.00 58.89  ? 284 TYR R N   1 
ATOM   1832 C  CA  . TYR A 1 405 ? 123.120 135.552 104.251 1.00 52.11  ? 284 TYR R CA  1 
ATOM   1833 C  C   . TYR A 1 405 ? 123.792 136.745 104.909 1.00 55.11  ? 284 TYR R C   1 
ATOM   1834 O  O   . TYR A 1 405 ? 124.585 136.564 105.837 1.00 60.66  ? 284 TYR R O   1 
ATOM   1835 C  CB  . TYR A 1 405 ? 124.054 134.959 103.196 1.00 53.49  ? 284 TYR R CB  1 
ATOM   1836 C  CG  . TYR A 1 405 ? 123.418 133.887 102.346 1.00 55.87  ? 284 TYR R CG  1 
ATOM   1837 C  CD1 . TYR A 1 405 ? 122.388 133.102 102.836 1.00 55.97  ? 284 TYR R CD1 1 
ATOM   1838 C  CD2 . TYR A 1 405 ? 123.845 133.664 101.051 1.00 57.65  ? 284 TYR R CD2 1 
ATOM   1839 C  CE1 . TYR A 1 405 ? 121.801 132.137 102.064 1.00 55.77  ? 284 TYR R CE1 1 
ATOM   1840 C  CE2 . TYR A 1 405 ? 123.267 132.695 100.272 1.00 58.52  ? 284 TYR R CE2 1 
ATOM   1841 C  CZ  . TYR A 1 405 ? 122.244 131.936 100.785 1.00 60.08  ? 284 TYR R CZ  1 
ATOM   1842 O  OH  . TYR A 1 405 ? 121.660 130.965 100.011 1.00 64.51  ? 284 TYR R OH  1 
ATOM   1843 N  N   . LEU A 1 406 ? 123.509 137.961 104.435 1.00 55.79  ? 285 LEU R N   1 
ATOM   1844 C  CA  . LEU A 1 406 ? 123.945 139.147 105.165 1.00 54.18  ? 285 LEU R CA  1 
ATOM   1845 C  C   . LEU A 1 406 ? 123.156 139.333 106.453 1.00 54.33  ? 285 LEU R C   1 
ATOM   1846 O  O   . LEU A 1 406 ? 123.654 139.951 107.399 1.00 54.78  ? 285 LEU R O   1 
ATOM   1847 C  CB  . LEU A 1 406 ? 123.803 140.394 104.298 1.00 54.64  ? 285 LEU R CB  1 
ATOM   1848 C  CG  . LEU A 1 406 ? 124.855 140.667 103.229 1.00 55.58  ? 285 LEU R CG  1 
ATOM   1849 C  CD1 . LEU A 1 406 ? 124.793 142.121 102.848 1.00 55.91  ? 285 LEU R CD1 1 
ATOM   1850 C  CD2 . LEU A 1 406 ? 126.240 140.298 103.713 1.00 56.30  ? 285 LEU R CD2 1 
ATOM   1851 N  N   . VAL A 1 407 ? 121.917 138.841 106.493 1.00 52.31  ? 286 VAL R N   1 
ATOM   1852 C  CA  . VAL A 1 407 ? 121.105 138.969 107.701 1.00 49.03  ? 286 VAL R CA  1 
ATOM   1853 C  C   . VAL A 1 407 ? 121.641 138.070 108.810 1.00 52.90  ? 286 VAL R C   1 
ATOM   1854 O  O   . VAL A 1 407 ? 121.656 138.453 109.988 1.00 56.81  ? 286 VAL R O   1 
ATOM   1855 C  CB  . VAL A 1 407 ? 119.629 138.665 107.387 1.00 49.32  ? 286 VAL R CB  1 
ATOM   1856 C  CG1 . VAL A 1 407 ? 118.830 138.543 108.663 1.00 52.22  ? 286 VAL R CG1 1 
ATOM   1857 C  CG2 . VAL A 1 407 ? 119.040 139.750 106.516 1.00 51.15  ? 286 VAL R CG2 1 
ATOM   1858 N  N   . LEU A 1 408 ? 122.084 136.861 108.458 1.00 48.11  ? 287 LEU R N   1 
ATOM   1859 C  CA  . LEU A 1 408 ? 122.533 135.911 109.469 1.00 43.25  ? 287 LEU R CA  1 
ATOM   1860 C  C   . LEU A 1 408 ? 123.775 136.403 110.199 1.00 43.57  ? 287 LEU R C   1 
ATOM   1861 O  O   . LEU A 1 408 ? 123.986 136.057 111.364 1.00 50.89  ? 287 LEU R O   1 
ATOM   1862 C  CB  . LEU A 1 408 ? 122.796 134.551 108.826 1.00 45.27  ? 287 LEU R CB  1 
ATOM   1863 C  CG  . LEU A 1 408 ? 121.580 133.798 108.286 1.00 43.96  ? 287 LEU R CG  1 
ATOM   1864 C  CD1 . LEU A 1 408 ? 122.012 132.563 107.533 1.00 42.62  ? 287 LEU R CD1 1 
ATOM   1865 C  CD2 . LEU A 1 408 ? 120.639 133.428 109.408 1.00 44.90  ? 287 LEU R CD2 1 
ATOM   1866 N  N   . ILE A 1 409 ? 124.597 137.222 109.547 1.00 42.00  ? 288 ILE R N   1 
ATOM   1867 C  CA  . ILE A 1 409 ? 125.788 137.754 110.201 1.00 41.92  ? 288 ILE R CA  1 
ATOM   1868 C  C   . ILE A 1 409 ? 125.405 138.740 111.301 1.00 46.17  ? 288 ILE R C   1 
ATOM   1869 O  O   . ILE A 1 409 ? 125.986 138.733 112.395 1.00 47.78  ? 288 ILE R O   1 
ATOM   1870 C  CB  . ILE A 1 409 ? 126.716 138.383 109.150 1.00 40.79  ? 288 ILE R CB  1 
ATOM   1871 C  CG1 . ILE A 1 409 ? 127.554 137.291 108.483 1.00 41.11  ? 288 ILE R CG1 1 
ATOM   1872 C  CG2 . ILE A 1 409 ? 127.587 139.453 109.775 1.00 43.19  ? 288 ILE R CG2 1 
ATOM   1873 C  CD1 . ILE A 1 409 ? 128.273 137.732 107.239 1.00 41.45  ? 288 ILE R CD1 1 
ATOM   1874 N  N   . MET A 1 410 ? 124.410 139.591 111.041 1.00 54.77  ? 289 MET R N   1 
ATOM   1875 C  CA  . MET A 1 410 ? 123.906 140.476 112.087 1.00 51.73  ? 289 MET R CA  1 
ATOM   1876 C  C   . MET A 1 410 ? 123.179 139.695 113.172 1.00 49.43  ? 289 MET R C   1 
ATOM   1877 O  O   . MET A 1 410 ? 123.212 140.085 114.344 1.00 50.77  ? 289 MET R O   1 
ATOM   1878 C  CB  . MET A 1 410 ? 122.992 141.537 111.481 1.00 49.09  ? 289 MET R CB  1 
ATOM   1879 C  CG  . MET A 1 410 ? 123.544 142.166 110.216 1.00 49.10  ? 289 MET R CG  1 
ATOM   1880 S  SD  . MET A 1 410 ? 122.571 143.565 109.651 1.00 59.08  ? 289 MET R SD  1 
ATOM   1881 C  CE  . MET A 1 410 ? 122.497 144.533 111.149 1.00 56.93  ? 289 MET R CE  1 
ATOM   1882 N  N   . CYS A 1 411 ? 122.532 138.587 112.807 1.00 44.92  ? 290 CYS R N   1 
ATOM   1883 C  CA  . CYS A 1 411 ? 121.967 137.698 113.820 1.00 44.29  ? 290 CYS R CA  1 
ATOM   1884 C  C   . CYS A 1 411 ? 123.057 137.148 114.734 1.00 45.70  ? 290 CYS R C   1 
ATOM   1885 O  O   . CYS A 1 411 ? 122.865 137.034 115.950 1.00 52.79  ? 290 CYS R O   1 
ATOM   1886 C  CB  . CYS A 1 411 ? 121.203 136.557 113.153 1.00 45.95  ? 290 CYS R CB  1 
ATOM   1887 S  SG  . CYS A 1 411 ? 119.466 136.903 112.848 1.00 62.19  ? 290 CYS R SG  1 
ATOM   1888 N  N   . ASN A 1 412 ? 124.203 136.787 114.160 1.00 42.70  ? 291 ASN R N   1 
ATOM   1889 C  CA  . ASN A 1 412 ? 125.336 136.350 114.969 1.00 41.15  ? 291 ASN R CA  1 
ATOM   1890 C  C   . ASN A 1 412 ? 125.827 137.464 115.880 1.00 42.41  ? 291 ASN R C   1 
ATOM   1891 O  O   . ASN A 1 412 ? 126.184 137.220 117.037 1.00 42.82  ? 291 ASN R O   1 
ATOM   1892 C  CB  . ASN A 1 412 ? 126.474 135.880 114.073 1.00 42.68  ? 291 ASN R CB  1 
ATOM   1893 C  CG  . ASN A 1 412 ? 127.707 135.516 114.857 1.00 49.58  ? 291 ASN R CG  1 
ATOM   1894 O  OD1 . ASN A 1 412 ? 128.823 135.844 114.465 1.00 54.18  ? 291 ASN R OD1 1 
ATOM   1895 N  ND2 . ASN A 1 412 ? 127.516 134.827 115.972 1.00 46.23  ? 291 ASN R ND2 1 
ATOM   1896 N  N   . SER A 1 413 ? 125.900 138.688 115.356 1.00 52.95  ? 292 SER R N   1 
ATOM   1897 C  CA  . SER A 1 413 ? 126.303 139.820 116.185 1.00 48.06  ? 292 SER R CA  1 
ATOM   1898 C  C   . SER A 1 413 ? 125.328 140.043 117.331 1.00 47.31  ? 292 SER R C   1 
ATOM   1899 O  O   . SER A 1 413 ? 125.725 140.511 118.402 1.00 50.44  ? 292 SER R O   1 
ATOM   1900 C  CB  . SER A 1 413 ? 126.419 141.081 115.335 1.00 48.08  ? 292 SER R CB  1 
ATOM   1901 O  OG  . SER A 1 413 ? 126.327 142.240 116.138 1.00 52.27  ? 292 SER R OG  1 
ATOM   1902 N  N   . VAL A 1 414 ? 124.049 139.732 117.119 1.00 50.96  ? 293 VAL R N   1 
ATOM   1903 C  CA  . VAL A 1 414 ? 123.071 139.808 118.202 1.00 50.18  ? 293 VAL R CA  1 
ATOM   1904 C  C   . VAL A 1 414 ? 123.310 138.702 119.225 1.00 49.04  ? 293 VAL R C   1 
ATOM   1905 O  O   . VAL A 1 414 ? 123.282 138.943 120.435 1.00 52.45  ? 293 VAL R O   1 
ATOM   1906 C  CB  . VAL A 1 414 ? 121.641 139.750 117.636 1.00 49.28  ? 293 VAL R CB  1 
ATOM   1907 C  CG1 . VAL A 1 414 ? 120.654 139.400 118.724 1.00 46.20  ? 293 VAL R CG1 1 
ATOM   1908 C  CG2 . VAL A 1 414 ? 121.269 141.070 116.991 1.00 51.19  ? 293 VAL R CG2 1 
ATOM   1909 N  N   . ILE A 1 415 ? 123.560 137.480 118.757 1.00 43.63  ? 294 ILE R N   1 
ATOM   1910 C  CA  . ILE A 1 415 ? 123.598 136.325 119.653 1.00 39.54  ? 294 ILE R CA  1 
ATOM   1911 C  C   . ILE A 1 415 ? 124.911 136.237 120.437 1.00 38.50  ? 294 ILE R C   1 
ATOM   1912 O  O   . ILE A 1 415 ? 124.940 135.666 121.531 1.00 40.54  ? 294 ILE R O   1 
ATOM   1913 C  CB  . ILE A 1 415 ? 123.328 135.043 118.843 1.00 41.80  ? 294 ILE R CB  1 
ATOM   1914 C  CG1 . ILE A 1 415 ? 121.900 135.058 118.297 1.00 44.78  ? 294 ILE R CG1 1 
ATOM   1915 C  CG2 . ILE A 1 415 ? 123.536 133.800 119.681 1.00 41.17  ? 294 ILE R CG2 1 
ATOM   1916 C  CD1 . ILE A 1 415 ? 121.606 133.956 117.315 1.00 43.49  ? 294 ILE R CD1 1 
ATOM   1917 N  N   . ASP A 1 416 ? 125.999 136.810 119.927 1.00 44.47  ? 295 ASP R N   1 
ATOM   1918 C  CA  . ASP A 1 416 ? 127.306 136.653 120.570 1.00 44.45  ? 295 ASP R CA  1 
ATOM   1919 C  C   . ASP A 1 416 ? 127.346 137.063 122.039 1.00 49.55  ? 295 ASP R C   1 
ATOM   1920 O  O   . ASP A 1 416 ? 127.889 136.295 122.848 1.00 50.17  ? 295 ASP R O   1 
ATOM   1921 C  CB  . ASP A 1 416 ? 128.368 137.428 119.780 1.00 43.91  ? 295 ASP R CB  1 
ATOM   1922 C  CG  . ASP A 1 416 ? 128.938 136.630 118.641 1.00 49.00  ? 295 ASP R CG  1 
ATOM   1923 O  OD1 . ASP A 1 416 ? 128.807 135.392 118.661 1.00 46.38  ? 295 ASP R OD1 1 
ATOM   1924 O  OD2 . ASP A 1 416 ? 129.518 137.242 117.723 1.00 49.98  ? 295 ASP R OD2 1 
ATOM   1925 N  N   . PRO A 1 417 ? 126.828 138.225 122.459 1.00 51.47  ? 296 PRO R N   1 
ATOM   1926 C  CA  . PRO A 1 417 ? 126.876 138.555 123.893 1.00 45.42  ? 296 PRO R CA  1 
ATOM   1927 C  C   . PRO A 1 417 ? 126.034 137.639 124.760 1.00 43.99  ? 296 PRO R C   1 
ATOM   1928 O  O   . PRO A 1 417 ? 126.195 137.657 125.985 1.00 44.68  ? 296 PRO R O   1 
ATOM   1929 C  CB  . PRO A 1 417 ? 126.359 139.996 123.940 1.00 47.79  ? 296 PRO R CB  1 
ATOM   1930 C  CG  . PRO A 1 417 ? 125.574 140.155 122.711 1.00 47.11  ? 296 PRO R CG  1 
ATOM   1931 C  CD  . PRO A 1 417 ? 126.280 139.349 121.680 1.00 47.76  ? 296 PRO R CD  1 
ATOM   1932 N  N   . LEU A 1 418 ? 125.131 136.855 124.172 1.00 48.15  ? 297 LEU R N   1 
ATOM   1933 C  CA  . LEU A 1 418 ? 124.283 135.961 124.950 1.00 46.05  ? 297 LEU R CA  1 
ATOM   1934 C  C   . LEU A 1 418 ? 125.033 134.715 125.404 1.00 44.78  ? 297 LEU R C   1 
ATOM   1935 O  O   . LEU A 1 418 ? 124.778 134.202 126.498 1.00 45.69  ? 297 LEU R O   1 
ATOM   1936 C  CB  . LEU A 1 418 ? 123.059 135.561 124.130 1.00 46.47  ? 297 LEU R CB  1 
ATOM   1937 C  CG  . LEU A 1 418 ? 121.710 136.160 124.511 1.00 45.78  ? 297 LEU R CG  1 
ATOM   1938 C  CD1 . LEU A 1 418 ? 121.642 137.613 124.100 1.00 44.03  ? 297 LEU R CD1 1 
ATOM   1939 C  CD2 . LEU A 1 418 ? 120.598 135.367 123.859 1.00 46.52  ? 297 LEU R CD2 1 
ATOM   1940 N  N   . ILE A 1 419 ? 125.951 134.207 124.583 1.00 38.50  ? 298 ILE R N   1 
ATOM   1941 C  CA  . ILE A 1 419 ? 126.615 132.937 124.846 1.00 38.28  ? 298 ILE R CA  1 
ATOM   1942 C  C   . ILE A 1 419 ? 128.042 133.106 125.323 1.00 36.49  ? 298 ILE R C   1 
ATOM   1943 O  O   . ILE A 1 419 ? 128.702 132.101 125.613 1.00 38.08  ? 298 ILE R O   1 
ATOM   1944 C  CB  . ILE A 1 419 ? 126.575 132.015 123.612 1.00 39.64  ? 298 ILE R CB  1 
ATOM   1945 C  CG1 . ILE A 1 419 ? 127.476 132.555 122.505 1.00 38.92  ? 298 ILE R CG1 1 
ATOM   1946 C  CG2 . ILE A 1 419 ? 125.152 131.848 123.116 1.00 36.22  ? 298 ILE R CG2 1 
ATOM   1947 C  CD1 . ILE A 1 419 ? 127.425 131.750 121.239 1.00 35.56  ? 298 ILE R CD1 1 
ATOM   1948 N  N   . TYR A 1 420 ? 128.547 134.331 125.416 1.00 33.53  ? 299 TYR R N   1 
ATOM   1949 C  CA  . TYR A 1 420 ? 129.908 134.555 125.885 1.00 36.79  ? 299 TYR R CA  1 
ATOM   1950 C  C   . TYR A 1 420 ? 129.966 135.380 127.159 1.00 41.14  ? 299 TYR R C   1 
ATOM   1951 O  O   . TYR A 1 420 ? 130.591 134.956 128.135 1.00 42.61  ? 299 TYR R O   1 
ATOM   1952 C  CB  . TYR A 1 420 ? 130.745 135.227 124.786 1.00 34.80  ? 299 TYR R CB  1 
ATOM   1953 C  CG  . TYR A 1 420 ? 131.310 134.249 123.785 1.00 32.29  ? 299 TYR R CG  1 
ATOM   1954 C  CD1 . TYR A 1 420 ? 132.340 133.398 124.130 1.00 31.64  ? 299 TYR R CD1 1 
ATOM   1955 C  CD2 . TYR A 1 420 ? 130.800 134.169 122.500 1.00 32.97  ? 299 TYR R CD2 1 
ATOM   1956 C  CE1 . TYR A 1 420 ? 132.847 132.503 123.230 1.00 39.28  ? 299 TYR R CE1 1 
ATOM   1957 C  CE2 . TYR A 1 420 ? 131.302 133.274 121.593 1.00 30.92  ? 299 TYR R CE2 1 
ATOM   1958 C  CZ  . TYR A 1 420 ? 132.327 132.443 121.963 1.00 37.30  ? 299 TYR R CZ  1 
ATOM   1959 O  OH  . TYR A 1 420 ? 132.843 131.546 121.060 1.00 31.58  ? 299 TYR R OH  1 
ATOM   1960 N  N   . ALA A 1 421 ? 129.331 136.549 127.181 1.00 54.81  ? 300 ALA R N   1 
ATOM   1961 C  CA  . ALA A 1 421 ? 129.379 137.415 128.350 1.00 53.03  ? 300 ALA R CA  1 
ATOM   1962 C  C   . ALA A 1 421 ? 128.206 137.184 129.291 1.00 54.17  ? 300 ALA R C   1 
ATOM   1963 O  O   . ALA A 1 421 ? 128.364 137.281 130.511 1.00 59.15  ? 300 ALA R O   1 
ATOM   1964 C  CB  . ALA A 1 421 ? 129.416 138.881 127.920 1.00 54.92  ? 300 ALA R CB  1 
ATOM   1965 N  N   . PHE A 1 422 ? 127.029 136.877 128.754 1.00 56.77  ? 301 PHE R N   1 
ATOM   1966 C  CA  . PHE A 1 422 ? 125.876 136.620 129.604 1.00 57.22  ? 301 PHE R CA  1 
ATOM   1967 C  C   . PHE A 1 422 ? 126.019 135.345 130.419 1.00 58.43  ? 301 PHE R C   1 
ATOM   1968 O  O   . PHE A 1 422 ? 125.216 135.123 131.329 1.00 60.39  ? 301 PHE R O   1 
ATOM   1969 C  CB  . PHE A 1 422 ? 124.602 136.548 128.763 1.00 59.72  ? 301 PHE R CB  1 
ATOM   1970 C  CG  . PHE A 1 422 ? 123.339 136.568 129.575 1.00 63.62  ? 301 PHE R CG  1 
ATOM   1971 C  CD1 . PHE A 1 422 ? 122.922 137.728 130.207 1.00 61.86  ? 301 PHE R CD1 1 
ATOM   1972 C  CD2 . PHE A 1 422 ? 122.567 135.425 129.708 1.00 63.75  ? 301 PHE R CD2 1 
ATOM   1973 C  CE1 . PHE A 1 422 ? 121.761 137.748 130.956 1.00 62.36  ? 301 PHE R CE1 1 
ATOM   1974 C  CE2 . PHE A 1 422 ? 121.402 135.440 130.456 1.00 62.21  ? 301 PHE R CE2 1 
ATOM   1975 C  CZ  . PHE A 1 422 ? 121.000 136.603 131.081 1.00 60.76  ? 301 PHE R CZ  1 
ATOM   1976 N  N   . ARG A 1 423 ? 127.001 134.501 130.117 1.00 53.83  ? 302 ARG R N   1 
ATOM   1977 C  CA  . ARG A 1 423 ? 127.188 133.280 130.882 1.00 57.17  ? 302 ARG R CA  1 
ATOM   1978 C  C   . ARG A 1 423 ? 128.179 133.442 132.024 1.00 58.36  ? 302 ARG R C   1 
ATOM   1979 O  O   . ARG A 1 423 ? 128.383 132.492 132.785 1.00 56.23  ? 302 ARG R O   1 
ATOM   1980 C  CB  . ARG A 1 423 ? 127.641 132.142 129.965 1.00 53.47  ? 302 ARG R CB  1 
ATOM   1981 C  CG  . ARG A 1 423 ? 127.060 132.204 128.570 1.00 54.09  ? 302 ARG R CG  1 
ATOM   1982 C  CD  . ARG A 1 423 ? 125.634 131.700 128.511 1.00 52.95  ? 302 ARG R CD  1 
ATOM   1983 N  NE  . ARG A 1 423 ? 125.420 130.483 129.280 1.00 52.77  ? 302 ARG R NE  1 
ATOM   1984 C  CZ  . ARG A 1 423 ? 124.559 130.379 130.281 1.00 56.52  ? 302 ARG R CZ  1 
ATOM   1985 N  NH1 . ARG A 1 423 ? 123.831 131.409 130.676 1.00 59.79  ? 302 ARG R NH1 1 
ATOM   1986 N  NH2 . ARG A 1 423 ? 124.421 129.212 130.901 1.00 52.37  ? 302 ARG R NH2 1 
ATOM   1987 N  N   . SER A 1 424 ? 128.789 134.613 132.167 1.00 73.73  ? 303 SER R N   1 
ATOM   1988 C  CA  . SER A 1 424 ? 129.689 134.871 133.281 1.00 75.72  ? 303 SER R CA  1 
ATOM   1989 C  C   . SER A 1 424 ? 128.895 135.376 134.477 1.00 77.53  ? 303 SER R C   1 
ATOM   1990 O  O   . SER A 1 424 ? 128.136 136.342 134.364 1.00 77.01  ? 303 SER R O   1 
ATOM   1991 C  CB  . SER A 1 424 ? 130.753 135.888 132.880 1.00 74.65  ? 303 SER R CB  1 
ATOM   1992 O  OG  . SER A 1 424 ? 131.425 136.388 134.019 1.00 75.82  ? 303 SER R OG  1 
ATOM   1993 N  N   . LEU A 1 425 ? 129.071 134.719 135.625 1.00 88.86  ? 304 LEU R N   1 
ATOM   1994 C  CA  . LEU A 1 425 ? 128.290 135.073 136.808 1.00 88.45  ? 304 LEU R CA  1 
ATOM   1995 C  C   . LEU A 1 425 ? 128.620 136.476 137.303 1.00 89.92  ? 304 LEU R C   1 
ATOM   1996 O  O   . LEU A 1 425 ? 127.726 137.205 137.743 1.00 89.93  ? 304 LEU R O   1 
ATOM   1997 C  CB  . LEU A 1 425 ? 128.518 134.048 137.916 1.00 89.59  ? 304 LEU R CB  1 
ATOM   1998 C  CG  . LEU A 1 425 ? 127.359 133.080 138.156 1.00 90.07  ? 304 LEU R CG  1 
ATOM   1999 C  CD1 . LEU A 1 425 ? 126.206 133.796 138.840 1.00 90.54  ? 304 LEU R CD1 1 
ATOM   2000 C  CD2 . LEU A 1 425 ? 126.899 132.445 136.857 1.00 87.32  ? 304 LEU R CD2 1 
ATOM   2001 N  N   . GLU A 1 426 ? 129.894 136.868 137.256 1.00 91.67  ? 305 GLU R N   1 
ATOM   2002 C  CA  . GLU A 1 426 ? 130.267 138.207 137.700 1.00 90.37  ? 305 GLU R CA  1 
ATOM   2003 C  C   . GLU A 1 426 ? 129.665 139.283 136.804 1.00 88.56  ? 305 GLU R C   1 
ATOM   2004 O  O   . GLU A 1 426 ? 129.135 140.283 137.301 1.00 89.61  ? 305 GLU R O   1 
ATOM   2005 C  CB  . GLU A 1 426 ? 131.786 138.337 137.746 1.00 90.45  ? 305 GLU R CB  1 
ATOM   2006 C  CG  . GLU A 1 426 ? 132.497 137.054 138.112 1.00 90.30  ? 305 GLU R CG  1 
ATOM   2007 C  CD  . GLU A 1 426 ? 133.946 137.285 138.472 1.00 92.47  ? 305 GLU R CD  1 
ATOM   2008 O  OE1 . GLU A 1 426 ? 134.326 138.458 138.674 1.00 93.56  ? 305 GLU R OE1 1 
ATOM   2009 O  OE2 . GLU A 1 426 ? 134.707 136.298 138.550 1.00 91.87  ? 305 GLU R OE2 1 
ATOM   2010 N  N   . LEU A 1 427 ? 129.740 139.102 135.484 1.00 85.26  ? 306 LEU R N   1 
ATOM   2011 C  CA  . LEU A 1 427 ? 129.132 140.069 134.576 1.00 85.68  ? 306 LEU R CA  1 
ATOM   2012 C  C   . LEU A 1 427 ? 127.619 140.093 134.729 1.00 88.06  ? 306 LEU R C   1 
ATOM   2013 O  O   . LEU A 1 427 ? 127.004 141.165 134.729 1.00 90.07  ? 306 LEU R O   1 
ATOM   2014 C  CB  . LEU A 1 427 ? 129.513 139.755 133.131 1.00 85.07  ? 306 LEU R CB  1 
ATOM   2015 C  CG  . LEU A 1 427 ? 130.969 139.976 132.726 1.00 86.75  ? 306 LEU R CG  1 
ATOM   2016 C  CD1 . LEU A 1 427 ? 131.057 140.201 131.233 1.00 85.68  ? 306 LEU R CD1 1 
ATOM   2017 C  CD2 . LEU A 1 427 ? 131.574 141.143 133.478 1.00 88.28  ? 306 LEU R CD2 1 
ATOM   2018 N  N   . ARG A 1 428 ? 126.998 138.921 134.863 1.00 89.12  ? 307 ARG R N   1 
ATOM   2019 C  CA  . ARG A 1 428 ? 125.553 138.874 135.045 1.00 89.38  ? 307 ARG R CA  1 
ATOM   2020 C  C   . ARG A 1 428 ? 125.137 139.516 136.361 1.00 90.07  ? 307 ARG R C   1 
ATOM   2021 O  O   . ARG A 1 428 ? 124.026 140.046 136.471 1.00 90.40  ? 307 ARG R O   1 
ATOM   2022 C  CB  . ARG A 1 428 ? 125.067 137.428 134.974 1.00 85.51  ? 307 ARG R CB  1 
ATOM   2023 C  CG  . ARG A 1 428 ? 123.631 137.290 134.536 1.00 86.08  ? 307 ARG R CG  1 
ATOM   2024 C  CD  . ARG A 1 428 ? 123.172 135.853 134.618 1.00 87.43  ? 307 ARG R CD  1 
ATOM   2025 N  NE  . ARG A 1 428 ? 124.213 134.923 134.203 1.00 86.11  ? 307 ARG R NE  1 
ATOM   2026 C  CZ  . ARG A 1 428 ? 124.218 133.632 134.497 1.00 87.84  ? 307 ARG R CZ  1 
ATOM   2027 N  NH1 . ARG A 1 428 ? 123.252 133.084 135.214 1.00 87.84  ? 307 ARG R NH1 1 
ATOM   2028 N  NH2 . ARG A 1 428 ? 125.214 132.869 134.058 1.00 86.54  ? 307 ARG R NH2 1 
ATOM   2029 N  N   . ASN A 1 429 ? 126.009 139.472 137.367 1.00 97.81  ? 308 ASN R N   1 
ATOM   2030 C  CA  . ASN A 1 429 ? 125.742 140.122 138.644 1.00 98.37  ? 308 ASN R CA  1 
ATOM   2031 C  C   . ASN A 1 429 ? 125.958 141.628 138.572 1.00 98.66  ? 308 ASN R C   1 
ATOM   2032 O  O   . ASN A 1 429 ? 125.288 142.379 139.290 1.00 100.65 ? 308 ASN R O   1 
ATOM   2033 C  CB  . ASN A 1 429 ? 126.629 139.506 139.729 1.00 98.65  ? 308 ASN R CB  1 
ATOM   2034 C  CG  . ASN A 1 429 ? 126.442 140.161 141.080 1.00 99.02  ? 308 ASN R CG  1 
ATOM   2035 O  OD1 . ASN A 1 429 ? 127.339 140.836 141.584 1.00 96.74  ? 308 ASN R OD1 1 
ATOM   2036 N  ND2 . ASN A 1 429 ? 125.274 139.961 141.677 1.00 98.85  ? 308 ASN R ND2 1 
ATOM   2037 N  N   . THR A 1 430 ? 126.884 142.084 137.724 1.00 97.71  ? 309 THR R N   1 
ATOM   2038 C  CA  . THR A 1 430 ? 127.138 143.517 137.611 1.00 97.59  ? 309 THR R CA  1 
ATOM   2039 C  C   . THR A 1 430 ? 125.908 144.261 137.106 1.00 98.67  ? 309 THR R C   1 
ATOM   2040 O  O   . THR A 1 430 ? 125.573 145.336 137.616 1.00 101.69 ? 309 THR R O   1 
ATOM   2041 C  CB  . THR A 1 430 ? 128.332 143.774 136.693 1.00 98.33  ? 309 THR R CB  1 
ATOM   2042 O  OG1 . THR A 1 430 ? 129.491 143.117 137.217 1.00 98.87  ? 309 THR R OG1 1 
ATOM   2043 C  CG2 . THR A 1 430 ? 128.612 145.261 136.600 1.00 97.35  ? 309 THR R CG2 1 
ATOM   2044 N  N   . PHE A 1 431 ? 125.219 143.709 136.111 1.00 93.15  ? 310 PHE R N   1 
ATOM   2045 C  CA  . PHE A 1 431 ? 123.968 144.306 135.655 1.00 95.03  ? 310 PHE R CA  1 
ATOM   2046 C  C   . PHE A 1 431 ? 122.784 143.423 136.038 1.00 94.65  ? 310 PHE R C   1 
ATOM   2047 O  O   . PHE A 1 431 ? 121.661 143.903 136.185 1.00 94.43  ? 310 PHE R O   1 
ATOM   2048 C  CB  . PHE A 1 431 ? 123.993 144.551 134.141 1.00 94.52  ? 310 PHE R CB  1 
ATOM   2049 C  CG  . PHE A 1 431 ? 123.893 143.301 133.309 1.00 96.42  ? 310 PHE R CG  1 
ATOM   2050 C  CD1 . PHE A 1 431 ? 122.658 142.779 132.956 1.00 95.18  ? 310 PHE R CD1 1 
ATOM   2051 C  CD2 . PHE A 1 431 ? 125.035 142.665 132.856 1.00 96.22  ? 310 PHE R CD2 1 
ATOM   2052 C  CE1 . PHE A 1 431 ? 122.567 141.638 132.189 1.00 95.21  ? 310 PHE R CE1 1 
ATOM   2053 C  CE2 . PHE A 1 431 ? 124.950 141.523 132.084 1.00 94.97  ? 310 PHE R CE2 1 
ATOM   2054 C  CZ  . PHE A 1 431 ? 123.716 141.009 131.751 1.00 95.49  ? 310 PHE R CZ  1 
ATOM   2055 N  N   . GLU B 2 21  ? 137.305 122.452 199.061 1.00 107.01 ? 3   GLU B N   1 
ATOM   2056 C  CA  . GLU B 2 21  ? 138.053 122.324 197.817 1.00 107.87 ? 3   GLU B CA  1 
ATOM   2057 C  C   . GLU B 2 21  ? 137.413 123.149 196.707 1.00 107.57 ? 3   GLU B C   1 
ATOM   2058 O  O   . GLU B 2 21  ? 137.215 124.353 196.854 1.00 107.42 ? 3   GLU B O   1 
ATOM   2059 C  CB  . GLU B 2 21  ? 138.148 120.855 197.393 1.00 107.59 ? 3   GLU B CB  1 
ATOM   2060 C  CG  . GLU B 2 21  ? 138.653 119.916 198.478 1.00 107.22 ? 3   GLU B CG  1 
ATOM   2061 C  CD  . GLU B 2 21  ? 140.120 120.131 198.811 1.00 109.23 ? 3   GLU B CD  1 
ATOM   2062 O  OE1 . GLU B 2 21  ? 140.882 120.548 197.914 1.00 109.26 ? 3   GLU B OE1 1 
ATOM   2063 O  OE2 . GLU B 2 21  ? 140.512 119.882 199.971 1.00 108.30 ? 3   GLU B OE2 1 
ATOM   2064 N  N   . LEU B 2 22  ? 137.095 122.489 195.592 1.00 107.65 ? 4   LEU B N   1 
ATOM   2065 C  CA  . LEU B 2 22  ? 136.488 123.179 194.460 1.00 107.20 ? 4   LEU B CA  1 
ATOM   2066 C  C   . LEU B 2 22  ? 135.006 123.458 194.689 1.00 107.30 ? 4   LEU B C   1 
ATOM   2067 O  O   . LEU B 2 22  ? 134.480 124.467 194.202 1.00 107.80 ? 4   LEU B O   1 
ATOM   2068 C  CB  . LEU B 2 22  ? 136.681 122.359 193.185 1.00 105.86 ? 4   LEU B CB  1 
ATOM   2069 C  CG  . LEU B 2 22  ? 137.629 122.956 192.143 1.00 106.86 ? 4   LEU B CG  1 
ATOM   2070 C  CD1 . LEU B 2 22  ? 137.580 122.169 190.844 1.00 106.08 ? 4   LEU B CD1 1 
ATOM   2071 C  CD2 . LEU B 2 22  ? 137.295 124.415 191.899 1.00 108.01 ? 4   LEU B CD2 1 
ATOM   2072 N  N   . ASP B 2 23  ? 134.318 122.577 195.418 1.00 108.60 ? 5   ASP B N   1 
ATOM   2073 C  CA  . ASP B 2 23  ? 132.871 122.703 195.569 1.00 109.05 ? 5   ASP B CA  1 
ATOM   2074 C  C   . ASP B 2 23  ? 132.492 123.974 196.321 1.00 109.14 ? 5   ASP B C   1 
ATOM   2075 O  O   . ASP B 2 23  ? 131.580 124.702 195.908 1.00 109.60 ? 5   ASP B O   1 
ATOM   2076 C  CB  . ASP B 2 23  ? 132.316 121.468 196.277 1.00 108.50 ? 5   ASP B CB  1 
ATOM   2077 C  CG  . ASP B 2 23  ? 132.867 120.177 195.706 1.00 108.82 ? 5   ASP B CG  1 
ATOM   2078 O  OD1 . ASP B 2 23  ? 133.186 120.150 194.498 1.00 108.78 ? 5   ASP B OD1 1 
ATOM   2079 O  OD2 . ASP B 2 23  ? 132.981 119.189 196.462 1.00 108.43 ? 5   ASP B OD2 1 
ATOM   2080 N  N   . GLN B 2 24  ? 133.182 124.260 197.428 1.00 107.45 ? 6   GLN B N   1 
ATOM   2081 C  CA  . GLN B 2 24  ? 132.876 125.465 198.192 1.00 108.21 ? 6   GLN B CA  1 
ATOM   2082 C  C   . GLN B 2 24  ? 133.170 126.719 197.382 1.00 107.45 ? 6   GLN B C   1 
ATOM   2083 O  O   . GLN B 2 24  ? 132.399 127.685 197.416 1.00 106.98 ? 6   GLN B O   1 
ATOM   2084 C  CB  . GLN B 2 24  ? 133.666 125.476 199.499 1.00 107.95 ? 6   GLN B CB  1 
ATOM   2085 C  CG  . GLN B 2 24  ? 134.041 124.100 200.008 1.00 108.09 ? 6   GLN B CG  1 
ATOM   2086 C  CD  . GLN B 2 24  ? 134.342 124.095 201.490 1.00 108.36 ? 6   GLN B CD  1 
ATOM   2087 O  OE1 . GLN B 2 24  ? 133.436 124.169 202.319 1.00 109.34 ? 6   GLN B OE1 1 
ATOM   2088 N  NE2 . GLN B 2 24  ? 135.622 124.013 201.833 1.00 108.02 ? 6   GLN B NE2 1 
ATOM   2089 N  N   . LEU B 2 25  ? 134.285 126.723 196.649 1.00 104.56 ? 7   LEU B N   1 
ATOM   2090 C  CA  . LEU B 2 25  ? 134.632 127.885 195.838 1.00 103.38 ? 7   LEU B CA  1 
ATOM   2091 C  C   . LEU B 2 25  ? 133.601 128.123 194.743 1.00 103.54 ? 7   LEU B C   1 
ATOM   2092 O  O   . LEU B 2 25  ? 133.220 129.269 194.477 1.00 104.25 ? 7   LEU B O   1 
ATOM   2093 C  CB  . LEU B 2 25  ? 136.026 127.704 195.241 1.00 103.21 ? 7   LEU B CB  1 
ATOM   2094 C  CG  . LEU B 2 25  ? 137.155 127.991 196.230 1.00 103.33 ? 7   LEU B CG  1 
ATOM   2095 C  CD1 . LEU B 2 25  ? 138.513 127.775 195.590 1.00 103.91 ? 7   LEU B CD1 1 
ATOM   2096 C  CD2 . LEU B 2 25  ? 137.028 129.404 196.771 1.00 102.74 ? 7   LEU B CD2 1 
ATOM   2097 N  N   . ARG B 2 26  ? 133.126 127.054 194.104 1.00 97.16  ? 8   ARG B N   1 
ATOM   2098 C  CA  . ARG B 2 26  ? 132.127 127.223 193.055 1.00 96.67  ? 8   ARG B CA  1 
ATOM   2099 C  C   . ARG B 2 26  ? 130.781 127.650 193.630 1.00 97.74  ? 8   ARG B C   1 
ATOM   2100 O  O   . ARG B 2 26  ? 130.060 128.443 193.011 1.00 98.14  ? 8   ARG B O   1 
ATOM   2101 C  CB  . ARG B 2 26  ? 132.004 125.935 192.245 1.00 96.80  ? 8   ARG B CB  1 
ATOM   2102 C  CG  . ARG B 2 26  ? 133.236 125.650 191.399 1.00 96.88  ? 8   ARG B CG  1 
ATOM   2103 C  CD  . ARG B 2 26  ? 133.095 124.365 190.611 1.00 97.88  ? 8   ARG B CD  1 
ATOM   2104 N  NE  . ARG B 2 26  ? 134.184 124.188 189.659 1.00 98.86  ? 8   ARG B NE  1 
ATOM   2105 C  CZ  . ARG B 2 26  ? 134.300 123.153 188.839 1.00 97.64  ? 8   ARG B CZ  1 
ATOM   2106 N  NH1 . ARG B 2 26  ? 133.413 122.172 188.836 1.00 94.29  ? 8   ARG B NH1 1 
ATOM   2107 N  NH2 . ARG B 2 26  ? 135.329 123.104 187.998 1.00 97.78  ? 8   ARG B NH2 1 
ATOM   2108 N  N   . GLN B 2 27  ? 130.429 127.155 194.820 1.00 104.09 ? 9   GLN B N   1 
ATOM   2109 C  CA  . GLN B 2 27  ? 129.216 127.632 195.480 1.00 105.58 ? 9   GLN B CA  1 
ATOM   2110 C  C   . GLN B 2 27  ? 129.317 129.117 195.804 1.00 106.18 ? 9   GLN B C   1 
ATOM   2111 O  O   . GLN B 2 27  ? 128.355 129.874 195.614 1.00 105.62 ? 9   GLN B O   1 
ATOM   2112 C  CB  . GLN B 2 27  ? 128.956 126.825 196.752 1.00 103.95 ? 9   GLN B CB  1 
ATOM   2113 C  CG  . GLN B 2 27  ? 127.847 125.800 196.626 1.00 105.12 ? 9   GLN B CG  1 
ATOM   2114 C  CD  . GLN B 2 27  ? 126.578 126.386 196.048 1.00 106.51 ? 9   GLN B CD  1 
ATOM   2115 O  OE1 . GLN B 2 27  ? 126.014 127.331 196.595 1.00 105.87 ? 9   GLN B OE1 1 
ATOM   2116 N  NE2 . GLN B 2 27  ? 126.119 125.824 194.938 1.00 105.32 ? 9   GLN B NE2 1 
ATOM   2117 N  N   . GLU B 2 28  ? 130.478 129.552 196.296 1.00 103.36 ? 10  GLU B N   1 
ATOM   2118 C  CA  . GLU B 2 28  ? 130.684 130.967 196.579 1.00 101.71 ? 10  GLU B CA  1 
ATOM   2119 C  C   . GLU B 2 28  ? 130.586 131.801 195.309 1.00 100.98 ? 10  GLU B C   1 
ATOM   2120 O  O   . GLU B 2 28  ? 130.010 132.895 195.318 1.00 101.85 ? 10  GLU B O   1 
ATOM   2121 C  CB  . GLU B 2 28  ? 132.040 131.168 197.250 1.00 102.00 ? 10  GLU B CB  1 
ATOM   2122 C  CG  . GLU B 2 28  ? 132.258 132.553 197.816 1.00 102.15 ? 10  GLU B CG  1 
ATOM   2123 C  CD  . GLU B 2 28  ? 133.449 132.610 198.750 1.00 102.93 ? 10  GLU B CD  1 
ATOM   2124 O  OE1 . GLU B 2 28  ? 134.148 131.583 198.886 1.00 102.91 ? 10  GLU B OE1 1 
ATOM   2125 O  OE2 . GLU B 2 28  ? 133.684 133.679 199.349 1.00 102.94 ? 10  GLU B OE2 1 
ATOM   2126 N  N   . ALA B 2 29  ? 131.152 131.302 194.207 1.00 100.95 ? 11  ALA B N   1 
ATOM   2127 C  CA  . ALA B 2 29  ? 131.069 132.023 192.942 1.00 101.25 ? 11  ALA B CA  1 
ATOM   2128 C  C   . ALA B 2 29  ? 129.627 132.147 192.468 1.00 101.56 ? 11  ALA B C   1 
ATOM   2129 O  O   . ALA B 2 29  ? 129.219 133.205 191.974 1.00 102.32 ? 11  ALA B O   1 
ATOM   2130 C  CB  . ALA B 2 29  ? 131.926 131.331 191.884 1.00 101.37 ? 11  ALA B CB  1 
ATOM   2131 N  N   . GLU B 2 30  ? 128.839 131.078 192.608 1.00 98.25  ? 12  GLU B N   1 
ATOM   2132 C  CA  . GLU B 2 30  ? 127.431 131.149 192.220 1.00 98.95  ? 12  GLU B CA  1 
ATOM   2133 C  C   . GLU B 2 30  ? 126.662 132.136 193.093 1.00 98.99  ? 12  GLU B C   1 
ATOM   2134 O  O   . GLU B 2 30  ? 125.812 132.889 192.596 1.00 99.16  ? 12  GLU B O   1 
ATOM   2135 C  CB  . GLU B 2 30  ? 126.795 129.762 192.289 1.00 98.70  ? 12  GLU B CB  1 
ATOM   2136 C  CG  . GLU B 2 30  ? 127.199 128.845 191.147 1.00 100.19 ? 12  GLU B CG  1 
ATOM   2137 C  CD  . GLU B 2 30  ? 127.086 129.515 189.790 1.00 101.07 ? 12  GLU B CD  1 
ATOM   2138 O  OE1 . GLU B 2 30  ? 126.043 130.145 189.518 1.00 99.57  ? 12  GLU B OE1 1 
ATOM   2139 O  OE2 . GLU B 2 30  ? 128.044 129.411 188.994 1.00 100.80 ? 12  GLU B OE2 1 
ATOM   2140 N  N   . GLN B 2 31  ? 126.950 132.149 194.397 1.00 95.56  ? 13  GLN B N   1 
ATOM   2141 C  CA  . GLN B 2 31  ? 126.299 133.110 195.284 1.00 95.22  ? 13  GLN B CA  1 
ATOM   2142 C  C   . GLN B 2 31  ? 126.654 134.544 194.906 1.00 95.10  ? 13  GLN B C   1 
ATOM   2143 O  O   . GLN B 2 31  ? 125.786 135.426 194.894 1.00 94.59  ? 13  GLN B O   1 
ATOM   2144 C  CB  . GLN B 2 31  ? 126.687 132.827 196.734 1.00 95.35  ? 13  GLN B CB  1 
ATOM   2145 C  CG  . GLN B 2 31  ? 126.116 133.824 197.728 1.00 96.34  ? 13  GLN B CG  1 
ATOM   2146 C  CD  . GLN B 2 31  ? 127.155 134.328 198.707 1.00 98.16  ? 13  GLN B CD  1 
ATOM   2147 O  OE1 . GLN B 2 31  ? 127.500 133.644 199.671 1.00 98.25  ? 13  GLN B OE1 1 
ATOM   2148 N  NE2 . GLN B 2 31  ? 127.662 135.531 198.465 1.00 96.40  ? 13  GLN B NE2 1 
ATOM   2149 N  N   . LEU B 2 32  ? 127.927 134.796 194.597 1.00 91.11  ? 14  LEU B N   1 
ATOM   2150 C  CA  . LEU B 2 32  ? 128.339 136.138 194.199 1.00 88.68  ? 14  LEU B CA  1 
ATOM   2151 C  C   . LEU B 2 32  ? 127.683 136.549 192.888 1.00 88.21  ? 14  LEU B C   1 
ATOM   2152 O  O   . LEU B 2 32  ? 127.278 137.705 192.725 1.00 91.22  ? 14  LEU B O   1 
ATOM   2153 C  CB  . LEU B 2 32  ? 129.860 136.211 194.084 1.00 91.09  ? 14  LEU B CB  1 
ATOM   2154 C  CG  . LEU B 2 32  ? 130.612 136.466 195.389 1.00 90.96  ? 14  LEU B CG  1 
ATOM   2155 C  CD1 . LEU B 2 32  ? 132.042 135.990 195.277 1.00 90.77  ? 14  LEU B CD1 1 
ATOM   2156 C  CD2 . LEU B 2 32  ? 130.563 137.936 195.752 1.00 89.85  ? 14  LEU B CD2 1 
ATOM   2157 N  N   . LYS B 2 33  ? 127.576 135.616 191.938 1.00 83.19  ? 15  LYS B N   1 
ATOM   2158 C  CA  . LYS B 2 33  ? 126.898 135.920 190.683 1.00 83.78  ? 15  LYS B CA  1 
ATOM   2159 C  C   . LYS B 2 33  ? 125.438 136.283 190.921 1.00 85.87  ? 15  LYS B C   1 
ATOM   2160 O  O   . LYS B 2 33  ? 124.919 137.229 190.315 1.00 86.17  ? 15  LYS B O   1 
ATOM   2161 C  CB  . LYS B 2 33  ? 127.002 134.734 189.727 1.00 83.92  ? 15  LYS B CB  1 
ATOM   2162 C  CG  . LYS B 2 33  ? 128.379 134.537 189.127 1.00 87.40  ? 15  LYS B CG  1 
ATOM   2163 C  CD  . LYS B 2 33  ? 128.297 133.761 187.826 1.00 88.68  ? 15  LYS B CD  1 
ATOM   2164 C  CE  . LYS B 2 33  ? 129.677 133.450 187.278 1.00 87.06  ? 15  LYS B CE  1 
ATOM   2165 N  NZ  . LYS B 2 33  ? 130.345 132.374 188.054 1.00 88.21  ? 15  LYS B NZ  1 
ATOM   2166 N  N   . ASN B 2 34  ? 124.759 135.541 191.799 1.00 85.54  ? 16  ASN B N   1 
ATOM   2167 C  CA  . ASN B 2 34  ? 123.368 135.860 192.108 1.00 82.78  ? 16  ASN B CA  1 
ATOM   2168 C  C   . ASN B 2 34  ? 123.244 137.228 192.769 1.00 83.48  ? 16  ASN B C   1 
ATOM   2169 O  O   . ASN B 2 34  ? 122.321 137.993 192.463 1.00 83.12  ? 16  ASN B O   1 
ATOM   2170 C  CB  . ASN B 2 34  ? 122.765 134.777 192.998 1.00 83.05  ? 16  ASN B CB  1 
ATOM   2171 C  CG  . ASN B 2 34  ? 122.012 133.735 192.205 1.00 84.56  ? 16  ASN B CG  1 
ATOM   2172 O  OD1 . ASN B 2 34  ? 122.279 133.527 191.023 1.00 82.58  ? 16  ASN B OD1 1 
ATOM   2173 N  ND2 . ASN B 2 34  ? 121.062 133.071 192.852 1.00 84.71  ? 16  ASN B ND2 1 
ATOM   2174 N  N   . GLN B 2 35  ? 124.161 137.554 193.684 1.00 82.70  ? 17  GLN B N   1 
ATOM   2175 C  CA  . GLN B 2 35  ? 124.123 138.867 194.322 1.00 82.38  ? 17  GLN B CA  1 
ATOM   2176 C  C   . GLN B 2 35  ? 124.330 139.983 193.305 1.00 82.36  ? 17  GLN B C   1 
ATOM   2177 O  O   . GLN B 2 35  ? 123.645 141.012 193.352 1.00 84.34  ? 17  GLN B O   1 
ATOM   2178 C  CB  . GLN B 2 35  ? 125.174 138.952 195.426 1.00 83.88  ? 17  GLN B CB  1 
ATOM   2179 C  CG  . GLN B 2 35  ? 125.109 140.231 196.238 1.00 83.02  ? 17  GLN B CG  1 
ATOM   2180 C  CD  . GLN B 2 35  ? 126.047 140.213 197.426 1.00 84.74  ? 17  GLN B CD  1 
ATOM   2181 O  OE1 . GLN B 2 35  ? 126.691 139.204 197.707 1.00 85.73  ? 17  GLN B OE1 1 
ATOM   2182 N  NE2 . GLN B 2 35  ? 126.126 141.334 198.132 1.00 83.93  ? 17  GLN B NE2 1 
ATOM   2183 N  N   . ILE B 2 36  ? 125.274 139.798 192.379 1.00 77.92  ? 18  ILE B N   1 
ATOM   2184 C  CA  . ILE B 2 36  ? 125.512 140.802 191.345 1.00 74.73  ? 18  ILE B CA  1 
ATOM   2185 C  C   . ILE B 2 36  ? 124.272 140.977 190.479 1.00 74.82  ? 18  ILE B C   1 
ATOM   2186 O  O   . ILE B 2 36  ? 123.876 142.105 190.153 1.00 76.76  ? 18  ILE B O   1 
ATOM   2187 C  CB  . ILE B 2 36  ? 126.741 140.419 190.502 1.00 75.90  ? 18  ILE B CB  1 
ATOM   2188 C  CG1 . ILE B 2 36  ? 128.014 140.516 191.337 1.00 74.29  ? 18  ILE B CG1 1 
ATOM   2189 C  CG2 . ILE B 2 36  ? 126.852 141.309 189.283 1.00 76.40  ? 18  ILE B CG2 1 
ATOM   2190 C  CD1 . ILE B 2 36  ? 129.268 140.236 190.553 1.00 74.72  ? 18  ILE B CD1 1 
ATOM   2191 N  N   . ARG B 2 37  ? 123.636 139.867 190.096 1.00 73.46  ? 19  ARG B N   1 
ATOM   2192 C  CA  . ARG B 2 37  ? 122.434 139.949 189.273 1.00 73.11  ? 19  ARG B CA  1 
ATOM   2193 C  C   . ARG B 2 37  ? 121.310 140.674 190.001 1.00 73.51  ? 19  ARG B C   1 
ATOM   2194 O  O   . ARG B 2 37  ? 120.589 141.478 189.400 1.00 73.62  ? 19  ARG B O   1 
ATOM   2195 C  CB  . ARG B 2 37  ? 121.986 138.550 188.858 1.00 75.17  ? 19  ARG B CB  1 
ATOM   2196 C  CG  . ARG B 2 37  ? 120.706 138.525 188.046 1.00 75.29  ? 19  ARG B CG  1 
ATOM   2197 C  CD  . ARG B 2 37  ? 120.220 137.103 187.833 1.00 74.53  ? 19  ARG B CD  1 
ATOM   2198 N  NE  . ARG B 2 37  ? 121.251 136.264 187.236 1.00 77.43  ? 19  ARG B NE  1 
ATOM   2199 C  CZ  . ARG B 2 37  ? 121.674 135.117 187.749 1.00 79.69  ? 19  ARG B CZ  1 
ATOM   2200 N  NH1 . ARG B 2 37  ? 121.160 134.628 188.865 1.00 77.32  ? 19  ARG B NH1 1 
ATOM   2201 N  NH2 . ARG B 2 37  ? 122.635 134.442 187.125 1.00 77.51  ? 19  ARG B NH2 1 
ATOM   2202 N  N   . ASP B 2 38  ? 121.138 140.401 191.295 1.00 73.83  ? 20  ASP B N   1 
ATOM   2203 C  CA  . ASP B 2 38  ? 120.089 141.078 192.053 1.00 73.10  ? 20  ASP B CA  1 
ATOM   2204 C  C   . ASP B 2 38  ? 120.376 142.568 192.196 1.00 73.78  ? 20  ASP B C   1 
ATOM   2205 O  O   . ASP B 2 38  ? 119.461 143.396 192.100 1.00 73.53  ? 20  ASP B O   1 
ATOM   2206 C  CB  . ASP B 2 38  ? 119.926 140.424 193.423 1.00 73.69  ? 20  ASP B CB  1 
ATOM   2207 C  CG  . ASP B 2 38  ? 118.903 139.308 193.413 1.00 76.12  ? 20  ASP B CG  1 
ATOM   2208 O  OD1 . ASP B 2 38  ? 118.035 139.309 192.515 1.00 77.21  ? 20  ASP B OD1 1 
ATOM   2209 O  OD2 . ASP B 2 38  ? 118.965 138.431 194.300 1.00 74.84  ? 20  ASP B OD2 1 
ATOM   2210 N  N   . ALA B 2 39  ? 121.638 142.931 192.429 1.00 74.44  ? 21  ALA B N   1 
ATOM   2211 C  CA  . ALA B 2 39  ? 121.994 144.345 192.499 1.00 71.47  ? 21  ALA B CA  1 
ATOM   2212 C  C   . ALA B 2 39  ? 121.718 145.046 191.176 1.00 71.06  ? 21  ALA B C   1 
ATOM   2213 O  O   . ALA B 2 39  ? 121.219 146.176 191.157 1.00 69.88  ? 21  ALA B O   1 
ATOM   2214 C  CB  . ALA B 2 39  ? 123.461 144.500 192.895 1.00 71.18  ? 21  ALA B CB  1 
ATOM   2215 N  N   . ARG B 2 40  ? 122.041 144.392 190.058 1.00 66.99  ? 22  ARG B N   1 
ATOM   2216 C  CA  . ARG B 2 40  ? 121.756 144.979 188.752 1.00 64.07  ? 22  ARG B CA  1 
ATOM   2217 C  C   . ARG B 2 40  ? 120.257 145.119 188.518 1.00 65.18  ? 22  ARG B C   1 
ATOM   2218 O  O   . ARG B 2 40  ? 119.803 146.123 187.961 1.00 66.65  ? 22  ARG B O   1 
ATOM   2219 C  CB  . ARG B 2 40  ? 122.391 144.139 187.648 1.00 62.12  ? 22  ARG B CB  1 
ATOM   2220 C  CG  . ARG B 2 40  ? 123.889 144.289 187.556 1.00 63.62  ? 22  ARG B CG  1 
ATOM   2221 C  CD  . ARG B 2 40  ? 124.424 143.650 186.296 1.00 62.34  ? 22  ARG B CD  1 
ATOM   2222 N  NE  . ARG B 2 40  ? 125.765 143.118 186.495 1.00 63.41  ? 22  ARG B NE  1 
ATOM   2223 C  CZ  . ARG B 2 40  ? 126.476 142.513 185.556 1.00 66.09  ? 22  ARG B CZ  1 
ATOM   2224 N  NH1 . ARG B 2 40  ? 126.008 142.355 184.329 1.00 67.06  ? 22  ARG B NH1 1 
ATOM   2225 N  NH2 . ARG B 2 40  ? 127.688 142.055 185.854 1.00 66.76  ? 22  ARG B NH2 1 
ATOM   2226 N  N   . LYS B 2 41  ? 119.473 144.118 188.924 1.00 70.61  ? 23  LYS B N   1 
ATOM   2227 C  CA  . LYS B 2 41  ? 118.024 144.200 188.778 1.00 69.43  ? 23  LYS B CA  1 
ATOM   2228 C  C   . LYS B 2 41  ? 117.415 145.291 189.648 1.00 69.18  ? 23  LYS B C   1 
ATOM   2229 O  O   . LYS B 2 41  ? 116.385 145.861 189.275 1.00 68.61  ? 23  LYS B O   1 
ATOM   2230 C  CB  . LYS B 2 41  ? 117.387 142.850 189.107 1.00 70.05  ? 23  LYS B CB  1 
ATOM   2231 C  CG  . LYS B 2 41  ? 115.871 142.851 189.085 1.00 70.57  ? 23  LYS B CG  1 
ATOM   2232 C  CD  . LYS B 2 41  ? 115.339 142.636 187.681 1.00 71.10  ? 23  LYS B CD  1 
ATOM   2233 C  CE  . LYS B 2 41  ? 114.162 141.680 187.681 1.00 71.49  ? 23  LYS B CE  1 
ATOM   2234 N  NZ  . LYS B 2 41  ? 113.487 141.630 189.007 1.00 71.28  ? 23  LYS B NZ  1 
ATOM   2235 N  N   . ALA B 2 42  ? 118.027 145.602 190.792 1.00 71.20  ? 24  ALA B N   1 
ATOM   2236 C  CA  . ALA B 2 42  ? 117.520 146.687 191.625 1.00 70.81  ? 24  ALA B CA  1 
ATOM   2237 C  C   . ALA B 2 42  ? 117.665 148.053 190.964 1.00 70.03  ? 24  ALA B C   1 
ATOM   2238 O  O   . ALA B 2 42  ? 116.976 148.996 191.365 1.00 67.42  ? 24  ALA B O   1 
ATOM   2239 C  CB  . ALA B 2 42  ? 118.232 146.689 192.976 1.00 68.92  ? 24  ALA B CB  1 
ATOM   2240 N  N   . CYS B 2 43  ? 118.542 148.183 189.971 1.00 70.36  ? 25  CYS B N   1 
ATOM   2241 C  CA  . CYS B 2 43  ? 118.765 149.448 189.287 1.00 66.32  ? 25  CYS B CA  1 
ATOM   2242 C  C   . CYS B 2 43  ? 117.931 149.605 188.025 1.00 66.70  ? 25  CYS B C   1 
ATOM   2243 O  O   . CYS B 2 43  ? 117.910 150.696 187.451 1.00 68.81  ? 25  CYS B O   1 
ATOM   2244 C  CB  . CYS B 2 43  ? 120.246 149.600 188.926 1.00 66.33  ? 25  CYS B CB  1 
ATOM   2245 S  SG  . CYS B 2 43  ? 121.369 149.595 190.334 1.00 71.44  ? 25  CYS B SG  1 
ATOM   2246 N  N   . ALA B 2 44  ? 117.241 148.555 187.580 1.00 73.99  ? 26  ALA B N   1 
ATOM   2247 C  CA  . ALA B 2 44  ? 116.450 148.618 186.352 1.00 74.66  ? 26  ALA B CA  1 
ATOM   2248 C  C   . ALA B 2 44  ? 115.157 149.386 186.624 1.00 76.62  ? 26  ALA B C   1 
ATOM   2249 O  O   . ALA B 2 44  ? 114.058 148.833 186.698 1.00 78.56  ? 26  ALA B O   1 
ATOM   2250 C  CB  . ALA B 2 44  ? 116.172 147.219 185.822 1.00 75.18  ? 26  ALA B CB  1 
ATOM   2251 N  N   . ASP B 2 45  ? 115.314 150.701 186.785 1.00 73.70  ? 27  ASP B N   1 
ATOM   2252 C  CA  . ASP B 2 45  ? 114.165 151.566 187.033 1.00 73.07  ? 27  ASP B CA  1 
ATOM   2253 C  C   . ASP B 2 45  ? 113.222 151.575 185.838 1.00 74.38  ? 27  ASP B C   1 
ATOM   2254 O  O   . ASP B 2 45  ? 112.003 151.442 185.989 1.00 74.31  ? 27  ASP B O   1 
ATOM   2255 C  CB  . ASP B 2 45  ? 114.647 152.981 187.352 1.00 73.16  ? 27  ASP B CB  1 
ATOM   2256 C  CG  . ASP B 2 45  ? 113.544 153.866 187.894 1.00 78.08  ? 27  ASP B CG  1 
ATOM   2257 O  OD1 . ASP B 2 45  ? 112.410 153.376 188.065 1.00 78.92  ? 27  ASP B OD1 1 
ATOM   2258 O  OD2 . ASP B 2 45  ? 113.812 155.059 188.145 1.00 77.35  ? 27  ASP B OD2 1 
ATOM   2259 N  N   . ALA B 2 46  ? 113.774 151.728 184.639 1.00 73.95  ? 28  ALA B N   1 
ATOM   2260 C  CA  . ALA B 2 46  ? 113.000 151.740 183.409 1.00 72.62  ? 28  ALA B CA  1 
ATOM   2261 C  C   . ALA B 2 46  ? 113.920 151.313 182.276 1.00 73.07  ? 28  ALA B C   1 
ATOM   2262 O  O   . ALA B 2 46  ? 115.091 150.995 182.491 1.00 76.11  ? 28  ALA B O   1 
ATOM   2263 C  CB  . ALA B 2 46  ? 112.387 153.118 183.152 1.00 71.52  ? 28  ALA B CB  1 
ATOM   2264 N  N   . THR B 2 47  ? 113.385 151.300 181.063 1.00 66.18  ? 29  THR B N   1 
ATOM   2265 C  CA  . THR B 2 47  ? 114.156 150.921 179.893 1.00 65.38  ? 29  THR B CA  1 
ATOM   2266 C  C   . THR B 2 47  ? 114.458 152.145 179.041 1.00 66.90  ? 29  THR B C   1 
ATOM   2267 O  O   . THR B 2 47  ? 113.807 153.185 179.155 1.00 65.11  ? 29  THR B O   1 
ATOM   2268 C  CB  . THR B 2 47  ? 113.416 149.874 179.056 1.00 65.20  ? 29  THR B CB  1 
ATOM   2269 O  OG1 . THR B 2 47  ? 112.239 150.457 178.495 1.00 66.71  ? 29  THR B OG1 1 
ATOM   2270 C  CG2 . THR B 2 47  ? 113.025 148.692 179.914 1.00 64.31  ? 29  THR B CG2 1 
ATOM   2271 N  N   . LEU B 2 48  ? 115.474 152.007 178.185 1.00 62.02  ? 30  LEU B N   1 
ATOM   2272 C  CA  . LEU B 2 48  ? 115.813 153.083 177.262 1.00 58.60  ? 30  LEU B CA  1 
ATOM   2273 C  C   . LEU B 2 48  ? 114.670 153.370 176.302 1.00 58.30  ? 30  LEU B C   1 
ATOM   2274 O  O   . LEU B 2 48  ? 114.478 154.520 175.897 1.00 64.26  ? 30  LEU B O   1 
ATOM   2275 C  CB  . LEU B 2 48  ? 117.084 152.732 176.488 1.00 57.89  ? 30  LEU B CB  1 
ATOM   2276 C  CG  . LEU B 2 48  ? 117.612 153.721 175.446 1.00 57.58  ? 30  LEU B CG  1 
ATOM   2277 C  CD1 . LEU B 2 48  ? 118.021 155.017 176.098 1.00 57.45  ? 30  LEU B CD1 1 
ATOM   2278 C  CD2 . LEU B 2 48  ? 118.785 153.130 174.700 1.00 53.75  ? 30  LEU B CD2 1 
ATOM   2279 N  N   . SER B 2 49  ? 113.898 152.346 175.935 1.00 57.29  ? 31  SER B N   1 
ATOM   2280 C  CA  . SER B 2 49  ? 112.810 152.544 174.984 1.00 60.03  ? 31  SER B CA  1 
ATOM   2281 C  C   . SER B 2 49  ? 111.720 153.446 175.550 1.00 62.26  ? 31  SER B C   1 
ATOM   2282 O  O   . SER B 2 49  ? 111.174 154.289 174.831 1.00 63.01  ? 31  SER B O   1 
ATOM   2283 C  CB  . SER B 2 49  ? 112.229 151.196 174.567 1.00 62.05  ? 31  SER B CB  1 
ATOM   2284 O  OG  . SER B 2 49  ? 113.184 150.432 173.855 1.00 62.03  ? 31  SER B OG  1 
ATOM   2285 N  N   . GLN B 2 50  ? 111.376 153.282 176.829 1.00 63.86  ? 32  GLN B N   1 
ATOM   2286 C  CA  . GLN B 2 50  ? 110.329 154.109 177.419 1.00 64.61  ? 32  GLN B CA  1 
ATOM   2287 C  C   . GLN B 2 50  ? 110.751 155.563 177.584 1.00 64.96  ? 32  GLN B C   1 
ATOM   2288 O  O   . GLN B 2 50  ? 109.885 156.440 177.650 1.00 64.21  ? 32  GLN B O   1 
ATOM   2289 C  CB  . GLN B 2 50  ? 109.902 153.546 178.774 1.00 62.62  ? 32  GLN B CB  1 
ATOM   2290 C  CG  . GLN B 2 50  ? 109.600 152.064 178.765 1.00 64.01  ? 32  GLN B CG  1 
ATOM   2291 C  CD  . GLN B 2 50  ? 109.335 151.512 180.152 1.00 65.51  ? 32  GLN B CD  1 
ATOM   2292 O  OE1 . GLN B 2 50  ? 109.643 152.150 181.157 1.00 64.73  ? 32  GLN B OE1 1 
ATOM   2293 N  NE2 . GLN B 2 50  ? 108.759 150.320 180.212 1.00 63.57  ? 32  GLN B NE2 1 
ATOM   2294 N  N   . ILE B 2 51  ? 112.049 155.837 177.657 1.00 65.14  ? 33  ILE B N   1 
ATOM   2295 C  CA  . ILE B 2 51  ? 112.529 157.205 177.826 1.00 64.01  ? 33  ILE B CA  1 
ATOM   2296 C  C   . ILE B 2 51  ? 112.648 157.920 176.488 1.00 64.39  ? 33  ILE B C   1 
ATOM   2297 O  O   . ILE B 2 51  ? 112.295 159.096 176.372 1.00 64.90  ? 33  ILE B O   1 
ATOM   2298 C  CB  . ILE B 2 51  ? 113.870 157.194 178.584 1.00 62.28  ? 33  ILE B CB  1 
ATOM   2299 C  CG1 . ILE B 2 51  ? 113.720 156.415 179.890 1.00 61.90  ? 33  ILE B CG1 1 
ATOM   2300 C  CG2 . ILE B 2 51  ? 114.341 158.609 178.852 1.00 60.22  ? 33  ILE B CG2 1 
ATOM   2301 C  CD1 . ILE B 2 51  ? 114.795 156.695 180.896 1.00 60.34  ? 33  ILE B CD1 1 
ATOM   2302 N  N   . THR B 2 52  ? 113.138 157.225 175.465 1.00 59.31  ? 34  THR B N   1 
ATOM   2303 C  CA  . THR B 2 52  ? 113.212 157.760 174.116 1.00 59.11  ? 34  THR B CA  1 
ATOM   2304 C  C   . THR B 2 52  ? 111.988 157.406 173.285 1.00 62.60  ? 34  THR B C   1 
ATOM   2305 O  O   . THR B 2 52  ? 112.101 157.250 172.065 1.00 63.33  ? 34  THR B O   1 
ATOM   2306 C  CB  . THR B 2 52  ? 114.476 157.262 173.419 1.00 58.99  ? 34  THR B CB  1 
ATOM   2307 O  OG1 . THR B 2 52  ? 114.260 155.936 172.928 1.00 58.48  ? 34  THR B OG1 1 
ATOM   2308 C  CG2 . THR B 2 52  ? 115.635 157.250 174.386 1.00 53.78  ? 34  THR B CG2 1 
ATOM   2309 N  N   . ASN B 2 53  ? 110.826 157.256 173.924 1.00 70.30  ? 35  ASN B N   1 
ATOM   2310 C  CA  . ASN B 2 53  ? 109.613 156.915 173.190 1.00 70.71  ? 35  ASN B CA  1 
ATOM   2311 C  C   . ASN B 2 53  ? 109.049 158.125 172.456 1.00 71.96  ? 35  ASN B C   1 
ATOM   2312 O  O   . ASN B 2 53  ? 108.527 157.999 171.343 1.00 69.01  ? 35  ASN B O   1 
ATOM   2313 C  CB  . ASN B 2 53  ? 108.572 156.337 174.146 1.00 69.10  ? 35  ASN B CB  1 
ATOM   2314 C  CG  . ASN B 2 53  ? 107.510 155.532 173.435 1.00 72.34  ? 35  ASN B CG  1 
ATOM   2315 O  OD1 . ASN B 2 53  ? 107.422 155.544 172.209 1.00 74.33  ? 35  ASN B OD1 1 
ATOM   2316 N  ND2 . ASN B 2 53  ? 106.693 154.826 174.203 1.00 70.69  ? 35  ASN B ND2 1 
ATOM   2317 N  N   . ASN B 2 54  ? 109.147 159.307 173.060 1.00 77.21  ? 36  ASN B N   1 
ATOM   2318 C  CA  . ASN B 2 54  ? 108.589 160.535 172.497 1.00 76.67  ? 36  ASN B CA  1 
ATOM   2319 C  C   . ASN B 2 54  ? 109.650 161.376 171.802 1.00 76.59  ? 36  ASN B C   1 
ATOM   2320 O  O   . ASN B 2 54  ? 109.608 162.608 171.840 1.00 77.80  ? 36  ASN B O   1 
ATOM   2321 C  CB  . ASN B 2 54  ? 107.890 161.342 173.585 1.00 76.59  ? 36  ASN B CB  1 
ATOM   2322 C  CG  . ASN B 2 54  ? 106.676 160.630 174.147 1.00 79.69  ? 36  ASN B CG  1 
ATOM   2323 O  OD1 . ASN B 2 54  ? 106.587 160.387 175.350 1.00 81.44  ? 36  ASN B OD1 1 
ATOM   2324 N  ND2 . ASN B 2 54  ? 105.735 160.286 173.276 1.00 78.66  ? 36  ASN B ND2 1 
ATOM   2325 N  N   . ILE B 2 55  ? 110.616 160.728 171.160 1.00 70.24  ? 37  ILE B N   1 
ATOM   2326 C  CA  . ILE B 2 55  ? 111.691 161.397 170.440 1.00 70.53  ? 37  ILE B CA  1 
ATOM   2327 C  C   . ILE B 2 55  ? 111.401 161.292 168.950 1.00 69.36  ? 37  ILE B C   1 
ATOM   2328 O  O   . ILE B 2 55  ? 110.998 160.231 168.460 1.00 67.81  ? 37  ILE B O   1 
ATOM   2329 C  CB  . ILE B 2 55  ? 113.063 160.787 170.797 1.00 69.41  ? 37  ILE B CB  1 
ATOM   2330 C  CG1 . ILE B 2 55  ? 113.659 161.500 172.006 1.00 67.39  ? 37  ILE B CG1 1 
ATOM   2331 C  CG2 . ILE B 2 55  ? 114.025 160.852 169.625 1.00 68.81  ? 37  ILE B CG2 1 
ATOM   2332 C  CD1 . ILE B 2 55  ? 113.780 162.985 171.828 1.00 67.60  ? 37  ILE B CD1 1 
ATOM   2333 N  N   . ASP B 2 56  ? 111.577 162.399 168.236 1.00 65.23  ? 38  ASP B N   1 
ATOM   2334 C  CA  . ASP B 2 56  ? 111.334 162.407 166.802 1.00 64.42  ? 38  ASP B CA  1 
ATOM   2335 C  C   . ASP B 2 56  ? 112.303 161.458 166.103 1.00 65.99  ? 38  ASP B C   1 
ATOM   2336 O  O   . ASP B 2 56  ? 113.512 161.517 166.359 1.00 67.22  ? 38  ASP B O   1 
ATOM   2337 C  CB  . ASP B 2 56  ? 111.488 163.820 166.245 1.00 66.53  ? 38  ASP B CB  1 
ATOM   2338 C  CG  . ASP B 2 56  ? 110.518 164.113 165.118 1.00 68.71  ? 38  ASP B CG  1 
ATOM   2339 O  OD1 . ASP B 2 56  ? 109.375 163.614 165.172 1.00 69.42  ? 38  ASP B OD1 1 
ATOM   2340 O  OD2 . ASP B 2 56  ? 110.899 164.839 164.176 1.00 68.02  ? 38  ASP B OD2 1 
ATOM   2341 N  N   . PRO B 2 57  ? 111.823 160.580 165.229 1.00 61.69  ? 39  PRO B N   1 
ATOM   2342 C  CA  . PRO B 2 57  ? 112.719 159.629 164.566 1.00 59.95  ? 39  PRO B CA  1 
ATOM   2343 C  C   . PRO B 2 57  ? 113.692 160.320 163.626 1.00 60.39  ? 39  PRO B C   1 
ATOM   2344 O  O   . PRO B 2 57  ? 113.453 161.421 163.129 1.00 63.52  ? 39  PRO B O   1 
ATOM   2345 C  CB  . PRO B 2 57  ? 111.764 158.714 163.794 1.00 59.81  ? 39  PRO B CB  1 
ATOM   2346 C  CG  . PRO B 2 57  ? 110.500 159.463 163.695 1.00 60.87  ? 39  PRO B CG  1 
ATOM   2347 C  CD  . PRO B 2 57  ? 110.412 160.322 164.908 1.00 60.21  ? 39  PRO B CD  1 
ATOM   2348 N  N   . VAL B 2 58  ? 114.821 159.646 163.396 1.00 53.66  ? 40  VAL B N   1 
ATOM   2349 C  CA  . VAL B 2 58  ? 115.848 160.186 162.510 1.00 54.60  ? 40  VAL B CA  1 
ATOM   2350 C  C   . VAL B 2 58  ? 115.309 160.323 161.091 1.00 58.01  ? 40  VAL B C   1 
ATOM   2351 O  O   . VAL B 2 58  ? 115.559 161.323 160.408 1.00 57.75  ? 40  VAL B O   1 
ATOM   2352 C  CB  . VAL B 2 58  ? 117.109 159.303 162.565 1.00 52.43  ? 40  VAL B CB  1 
ATOM   2353 C  CG1 . VAL B 2 58  ? 117.818 159.285 161.233 1.00 54.25  ? 40  VAL B CG1 1 
ATOM   2354 C  CG2 . VAL B 2 58  ? 118.043 159.799 163.639 1.00 48.83  ? 40  VAL B CG2 1 
ATOM   2355 N  N   . GLY B 2 59  ? 114.554 159.332 160.632 1.00 64.08  ? 41  GLY B N   1 
ATOM   2356 C  CA  . GLY B 2 59  ? 114.003 159.366 159.294 1.00 62.97  ? 41  GLY B CA  1 
ATOM   2357 C  C   . GLY B 2 59  ? 114.593 158.299 158.399 1.00 64.81  ? 41  GLY B C   1 
ATOM   2358 O  O   . GLY B 2 59  ? 114.657 157.126 158.778 1.00 65.46  ? 41  GLY B O   1 
ATOM   2359 N  N   . ARG B 2 60  ? 115.017 158.691 157.204 1.00 55.35  ? 42  ARG B N   1 
ATOM   2360 C  CA  . ARG B 2 60  ? 115.682 157.796 156.272 1.00 52.38  ? 42  ARG B CA  1 
ATOM   2361 C  C   . ARG B 2 60  ? 117.056 158.363 155.969 1.00 51.56  ? 42  ARG B C   1 
ATOM   2362 O  O   . ARG B 2 60  ? 117.174 159.525 155.571 1.00 56.44  ? 42  ARG B O   1 
ATOM   2363 C  CB  . ARG B 2 60  ? 114.874 157.633 154.986 1.00 53.08  ? 42  ARG B CB  1 
ATOM   2364 C  CG  . ARG B 2 60  ? 115.305 156.462 154.123 1.00 53.39  ? 42  ARG B CG  1 
ATOM   2365 C  CD  . ARG B 2 60  ? 114.134 155.915 153.317 1.00 56.65  ? 42  ARG B CD  1 
ATOM   2366 N  NE  . ARG B 2 60  ? 113.696 156.839 152.278 1.00 57.33  ? 42  ARG B NE  1 
ATOM   2367 C  CZ  . ARG B 2 60  ? 112.628 157.619 152.368 1.00 58.09  ? 42  ARG B CZ  1 
ATOM   2368 N  NH1 . ARG B 2 60  ? 111.860 157.618 153.445 1.00 55.48  ? 42  ARG B NH1 1 
ATOM   2369 N  NH2 . ARG B 2 60  ? 112.323 158.423 151.353 1.00 57.10  ? 42  ARG B NH2 1 
ATOM   2370 N  N   . ILE B 2 61  ? 118.086 157.552 156.162 1.00 39.17  ? 43  ILE B N   1 
ATOM   2371 C  CA  . ILE B 2 61  ? 119.468 157.980 156.002 1.00 40.00  ? 43  ILE B CA  1 
ATOM   2372 C  C   . ILE B 2 61  ? 119.995 157.352 154.722 1.00 44.36  ? 43  ILE B C   1 
ATOM   2373 O  O   . ILE B 2 61  ? 120.148 156.128 154.638 1.00 40.18  ? 43  ILE B O   1 
ATOM   2374 C  CB  . ILE B 2 61  ? 120.324 157.592 157.212 1.00 37.26  ? 43  ILE B CB  1 
ATOM   2375 C  CG1 . ILE B 2 61  ? 119.859 158.350 158.453 1.00 38.34  ? 43  ILE B CG1 1 
ATOM   2376 C  CG2 . ILE B 2 61  ? 121.780 157.861 156.942 1.00 36.07  ? 43  ILE B CG2 1 
ATOM   2377 C  CD1 . ILE B 2 61  ? 120.316 159.777 158.508 1.00 39.88  ? 43  ILE B CD1 1 
ATOM   2378 N  N   . GLN B 2 62  ? 120.274 158.188 153.726 1.00 42.33  ? 44  GLN B N   1 
ATOM   2379 C  CA  . GLN B 2 62  ? 120.780 157.746 152.435 1.00 42.03  ? 44  GLN B CA  1 
ATOM   2380 C  C   . GLN B 2 62  ? 122.183 158.292 152.233 1.00 42.07  ? 44  GLN B C   1 
ATOM   2381 O  O   . GLN B 2 62  ? 122.422 159.486 152.431 1.00 44.03  ? 44  GLN B O   1 
ATOM   2382 C  CB  . GLN B 2 62  ? 119.855 158.195 151.301 1.00 40.97  ? 44  GLN B CB  1 
ATOM   2383 C  CG  . GLN B 2 62  ? 118.956 157.087 150.773 1.00 46.38  ? 44  GLN B CG  1 
ATOM   2384 C  CD  . GLN B 2 62  ? 117.553 157.560 150.450 1.00 48.90  ? 44  GLN B CD  1 
ATOM   2385 O  OE1 . GLN B 2 62  ? 117.268 158.756 150.463 1.00 48.38  ? 44  GLN B OE1 1 
ATOM   2386 N  NE2 . GLN B 2 62  ? 116.667 156.617 150.163 1.00 43.97  ? 44  GLN B NE2 1 
ATOM   2387 N  N   . MET B 2 63  ? 123.105 157.417 151.848 1.00 33.75  ? 45  MET B N   1 
ATOM   2388 C  CA  . MET B 2 63  ? 124.500 157.775 151.656 1.00 28.46  ? 45  MET B CA  1 
ATOM   2389 C  C   . MET B 2 63  ? 124.943 157.336 150.271 1.00 30.03  ? 45  MET B C   1 
ATOM   2390 O  O   . MET B 2 63  ? 124.413 156.374 149.712 1.00 36.67  ? 45  MET B O   1 
ATOM   2391 C  CB  . MET B 2 63  ? 125.399 157.129 152.713 1.00 33.38  ? 45  MET B CB  1 
ATOM   2392 C  CG  . MET B 2 63  ? 125.845 158.069 153.811 1.00 31.75  ? 45  MET B CG  1 
ATOM   2393 S  SD  . MET B 2 63  ? 126.302 157.218 155.321 1.00 45.14  ? 45  MET B SD  1 
ATOM   2394 C  CE  . MET B 2 63  ? 125.277 158.075 156.499 1.00 33.15  ? 45  MET B CE  1 
ATOM   2395 N  N   . ARG B 2 64  ? 125.920 158.049 149.721 1.00 21.70  ? 46  ARG B N   1 
ATOM   2396 C  CA  . ARG B 2 64  ? 126.404 157.789 148.375 1.00 25.69  ? 46  ARG B CA  1 
ATOM   2397 C  C   . ARG B 2 64  ? 127.917 157.653 148.385 1.00 20.23  ? 46  ARG B C   1 
ATOM   2398 O  O   . ARG B 2 64  ? 128.611 158.432 149.037 1.00 20.01  ? 46  ARG B O   1 
ATOM   2399 C  CB  . ARG B 2 64  ? 125.985 158.907 147.417 1.00 27.60  ? 46  ARG B CB  1 
ATOM   2400 N  N   . THR B 2 65  ? 128.423 156.668 147.649 1.00 13.22  ? 47  THR B N   1 
ATOM   2401 C  CA  . THR B 2 65  ? 129.860 156.442 147.563 1.00 11.43  ? 47  THR B CA  1 
ATOM   2402 C  C   . THR B 2 65  ? 130.518 157.615 146.855 1.00 22.36  ? 47  THR B C   1 
ATOM   2403 O  O   . THR B 2 65  ? 130.284 157.842 145.665 1.00 31.26  ? 47  THR B O   1 
ATOM   2404 C  CB  . THR B 2 65  ? 130.155 155.146 146.819 1.00 13.48  ? 47  THR B CB  1 
ATOM   2405 O  OG1 . THR B 2 65  ? 129.167 154.167 147.145 1.00 21.69  ? 47  THR B OG1 1 
ATOM   2406 C  CG2 . THR B 2 65  ? 131.519 154.621 147.191 1.00 14.65  ? 47  THR B CG2 1 
ATOM   2407 N  N   . ARG B 2 66  ? 131.351 158.357 147.580 1.00 20.49  ? 48  ARG B N   1 
ATOM   2408 C  CA  . ARG B 2 66  ? 132.141 159.413 146.962 1.00 16.60  ? 48  ARG B CA  1 
ATOM   2409 C  C   . ARG B 2 66  ? 133.340 158.835 146.222 1.00 19.62  ? 48  ARG B C   1 
ATOM   2410 O  O   . ARG B 2 66  ? 133.484 159.021 145.011 1.00 32.99  ? 48  ARG B O   1 
ATOM   2411 C  CB  . ARG B 2 66  ? 132.595 160.416 148.021 1.00 21.24  ? 48  ARG B CB  1 
ATOM   2412 C  CG  . ARG B 2 66  ? 131.467 161.099 148.746 1.00 20.84  ? 48  ARG B CG  1 
ATOM   2413 C  CD  . ARG B 2 66  ? 130.359 161.479 147.791 1.00 26.58  ? 48  ARG B CD  1 
ATOM   2414 N  NE  . ARG B 2 66  ? 129.266 162.164 148.467 1.00 37.89  ? 48  ARG B NE  1 
ATOM   2415 C  CZ  . ARG B 2 66  ? 128.106 162.460 147.900 1.00 34.94  ? 48  ARG B CZ  1 
ATOM   2416 N  NH1 . ARG B 2 66  ? 127.854 162.149 146.640 1.00 32.72  ? 48  ARG B NH1 1 
ATOM   2417 N  NH2 . ARG B 2 66  ? 127.175 163.083 148.615 1.00 28.11  ? 48  ARG B NH2 1 
ATOM   2418 N  N   . ARG B 2 67  ? 134.202 158.116 146.933 1.00 15.74  ? 49  ARG B N   1 
ATOM   2419 C  CA  . ARG B 2 67  ? 135.430 157.582 146.369 1.00 15.03  ? 49  ARG B CA  1 
ATOM   2420 C  C   . ARG B 2 67  ? 135.470 156.068 146.504 1.00 18.33  ? 49  ARG B C   1 
ATOM   2421 O  O   . ARG B 2 67  ? 134.899 155.494 147.434 1.00 23.79  ? 49  ARG B O   1 
ATOM   2422 C  CB  . ARG B 2 67  ? 136.656 158.177 147.056 1.00 15.43  ? 49  ARG B CB  1 
ATOM   2423 C  CG  . ARG B 2 67  ? 136.563 159.658 147.321 1.00 14.09  ? 49  ARG B CG  1 
ATOM   2424 C  CD  . ARG B 2 67  ? 137.215 160.430 146.200 1.00 24.46  ? 49  ARG B CD  1 
ATOM   2425 N  NE  . ARG B 2 67  ? 137.376 161.842 146.515 1.00 30.02  ? 49  ARG B NE  1 
ATOM   2426 C  CZ  . ARG B 2 67  ? 136.495 162.781 146.207 1.00 28.96  ? 49  ARG B CZ  1 
ATOM   2427 N  NH1 . ARG B 2 67  ? 135.360 162.487 145.598 1.00 27.01  ? 49  ARG B NH1 1 
ATOM   2428 N  NH2 . ARG B 2 67  ? 136.759 164.044 146.520 1.00 22.95  ? 49  ARG B NH2 1 
ATOM   2429 N  N   . THR B 2 68  ? 136.153 155.432 145.557 1.00 11.36  ? 50  THR B N   1 
ATOM   2430 C  CA  . THR B 2 68  ? 136.498 154.021 145.625 1.00 8.39   ? 50  THR B CA  1 
ATOM   2431 C  C   . THR B 2 68  ? 138.002 153.894 145.454 1.00 23.05  ? 50  THR B C   1 
ATOM   2432 O  O   . THR B 2 68  ? 138.563 154.390 144.473 1.00 25.35  ? 50  THR B O   1 
ATOM   2433 C  CB  . THR B 2 68  ? 135.777 153.206 144.553 1.00 11.31  ? 50  THR B CB  1 
ATOM   2434 O  OG1 . THR B 2 68  ? 134.372 153.202 144.821 1.00 20.71  ? 50  THR B OG1 1 
ATOM   2435 C  CG2 . THR B 2 68  ? 136.283 151.780 144.544 1.00 12.49  ? 50  THR B CG2 1 
ATOM   2436 N  N   . LEU B 2 69  ? 138.650 153.240 146.409 1.00 20.68  ? 51  LEU B N   1 
ATOM   2437 C  CA  . LEU B 2 69  ? 140.096 153.087 146.433 1.00 14.13  ? 51  LEU B CA  1 
ATOM   2438 C  C   . LEU B 2 69  ? 140.436 151.652 146.055 1.00 13.14  ? 51  LEU B C   1 
ATOM   2439 O  O   . LEU B 2 69  ? 139.992 150.709 146.727 1.00 20.84  ? 51  LEU B O   1 
ATOM   2440 C  CB  . LEU B 2 69  ? 140.651 153.451 147.809 1.00 11.06  ? 51  LEU B CB  1 
ATOM   2441 C  CG  . LEU B 2 69  ? 139.955 154.594 148.557 1.00 6.91   ? 51  LEU B CG  1 
ATOM   2442 C  CD1 . LEU B 2 69  ? 140.283 154.558 150.025 1.00 13.42  ? 51  LEU B CD1 1 
ATOM   2443 C  CD2 . LEU B 2 69  ? 140.331 155.935 147.995 1.00 12.99  ? 51  LEU B CD2 1 
ATOM   2444 N  N   . ARG B 2 70  ? 141.217 151.504 144.977 1.00 11.80  ? 52  ARG B N   1 
ATOM   2445 C  CA  . ARG B 2 70  ? 141.575 150.221 144.367 1.00 12.89  ? 52  ARG B CA  1 
ATOM   2446 C  C   . ARG B 2 70  ? 143.092 150.120 144.241 1.00 17.98  ? 52  ARG B C   1 
ATOM   2447 O  O   . ARG B 2 70  ? 143.672 150.680 143.310 1.00 24.41  ? 52  ARG B O   1 
ATOM   2448 C  CB  . ARG B 2 70  ? 140.951 150.065 142.986 1.00 11.36  ? 52  ARG B CB  1 
ATOM   2449 C  CG  . ARG B 2 70  ? 139.565 150.619 142.808 1.00 20.09  ? 52  ARG B CG  1 
ATOM   2450 C  CD  . ARG B 2 70  ? 139.153 150.513 141.350 1.00 25.58  ? 52  ARG B CD  1 
ATOM   2451 N  NE  . ARG B 2 70  ? 137.806 151.012 141.114 1.00 29.63  ? 52  ARG B NE  1 
ATOM   2452 C  CZ  . ARG B 2 70  ? 137.502 152.291 140.955 1.00 28.76  ? 52  ARG B CZ  1 
ATOM   2453 N  NH1 . ARG B 2 70  ? 138.429 153.233 141.007 1.00 20.29  ? 52  ARG B NH1 1 
ATOM   2454 N  NH2 . ARG B 2 70  ? 136.235 152.635 140.738 1.00 26.83  ? 52  ARG B NH2 1 
ATOM   2455 N  N   . GLY B 2 71  ? 143.743 149.427 145.167 1.00 22.94  ? 53  GLY B N   1 
ATOM   2456 C  CA  . GLY B 2 71  ? 145.149 149.129 144.992 1.00 11.58  ? 53  GLY B CA  1 
ATOM   2457 C  C   . GLY B 2 71  ? 145.587 147.798 145.561 1.00 20.38  ? 53  GLY B C   1 
ATOM   2458 O  O   . GLY B 2 71  ? 146.760 147.436 145.454 1.00 24.07  ? 53  GLY B O   1 
ATOM   2459 N  N   . HIS B 2 72  ? 144.659 147.057 146.157 1.00 22.32  ? 54  HIS B N   1 
ATOM   2460 C  CA  . HIS B 2 72  ? 144.974 145.854 146.916 1.00 12.89  ? 54  HIS B CA  1 
ATOM   2461 C  C   . HIS B 2 72  ? 144.664 144.615 146.087 1.00 10.58  ? 54  HIS B C   1 
ATOM   2462 O  O   . HIS B 2 72  ? 143.666 144.574 145.364 1.00 15.15  ? 54  HIS B O   1 
ATOM   2463 C  CB  . HIS B 2 72  ? 144.184 145.815 148.229 1.00 18.91  ? 54  HIS B CB  1 
ATOM   2464 C  CG  . HIS B 2 72  ? 144.796 146.610 149.344 1.00 18.73  ? 54  HIS B CG  1 
ATOM   2465 N  ND1 . HIS B 2 72  ? 146.142 146.584 149.631 1.00 20.33  ? 54  HIS B ND1 1 
ATOM   2466 C  CD2 . HIS B 2 72  ? 144.237 147.439 150.256 1.00 9.66   ? 54  HIS B CD2 1 
ATOM   2467 C  CE1 . HIS B 2 72  ? 146.387 147.368 150.664 1.00 1.28   ? 54  HIS B CE1 1 
ATOM   2468 N  NE2 . HIS B 2 72  ? 145.248 147.900 151.061 1.00 0.00   ? 54  HIS B NE2 1 
ATOM   2469 N  N   . LEU B 2 73  ? 145.528 143.606 146.192 1.00 13.86  ? 55  LEU B N   1 
ATOM   2470 C  CA  . LEU B 2 73  ? 145.350 142.383 145.417 1.00 14.64  ? 55  LEU B CA  1 
ATOM   2471 C  C   . LEU B 2 73  ? 144.459 141.377 146.133 1.00 18.20  ? 55  LEU B C   1 
ATOM   2472 O  O   . LEU B 2 73  ? 143.668 140.680 145.491 1.00 26.02  ? 55  LEU B O   1 
ATOM   2473 C  CB  . LEU B 2 73  ? 146.707 141.751 145.115 1.00 14.53  ? 55  LEU B CB  1 
ATOM   2474 C  CG  . LEU B 2 73  ? 147.781 142.662 144.535 1.00 19.31  ? 55  LEU B CG  1 
ATOM   2475 C  CD1 . LEU B 2 73  ? 149.104 141.950 144.500 1.00 14.89  ? 55  LEU B CD1 1 
ATOM   2476 C  CD2 . LEU B 2 73  ? 147.385 143.116 143.157 1.00 23.16  ? 55  LEU B CD2 1 
ATOM   2477 N  N   . ALA B 2 74  ? 144.573 141.282 147.450 1.00 10.55  ? 56  ALA B N   1 
ATOM   2478 C  CA  . ALA B 2 74  ? 143.820 140.335 148.252 1.00 9.83   ? 56  ALA B CA  1 
ATOM   2479 C  C   . ALA B 2 74  ? 142.823 141.076 149.136 1.00 15.78  ? 56  ALA B C   1 
ATOM   2480 O  O   . ALA B 2 74  ? 142.701 142.299 149.086 1.00 17.67  ? 56  ALA B O   1 
ATOM   2481 C  CB  . ALA B 2 74  ? 144.766 139.476 149.086 1.00 10.66  ? 56  ALA B CB  1 
ATOM   2482 N  N   . LYS B 2 75  ? 142.117 140.313 149.965 1.00 17.17  ? 57  LYS B N   1 
ATOM   2483 C  CA  . LYS B 2 75  ? 141.085 140.868 150.828 1.00 16.56  ? 57  LYS B CA  1 
ATOM   2484 C  C   . LYS B 2 75  ? 141.675 141.820 151.862 1.00 24.43  ? 57  LYS B C   1 
ATOM   2485 O  O   . LYS B 2 75  ? 142.824 141.682 152.284 1.00 32.88  ? 57  LYS B O   1 
ATOM   2486 C  CB  . LYS B 2 75  ? 140.328 139.742 151.527 1.00 7.54   ? 57  LYS B CB  1 
ATOM   2487 C  CG  . LYS B 2 75  ? 141.206 138.805 152.328 1.00 1.96   ? 57  LYS B CG  1 
ATOM   2488 C  CD  . LYS B 2 75  ? 140.390 137.711 152.978 1.00 18.06  ? 57  LYS B CD  1 
ATOM   2489 C  CE  . LYS B 2 75  ? 141.248 136.802 153.831 1.00 17.96  ? 57  LYS B CE  1 
ATOM   2490 N  NZ  . LYS B 2 75  ? 141.894 135.731 153.035 1.00 16.50  ? 57  LYS B NZ  1 
ATOM   2491 N  N   . ILE B 2 76  ? 140.870 142.795 152.269 1.00 11.29  ? 58  ILE B N   1 
ATOM   2492 C  CA  . ILE B 2 76  ? 141.278 143.825 153.219 1.00 15.37  ? 58  ILE B CA  1 
ATOM   2493 C  C   . ILE B 2 76  ? 140.811 143.418 154.605 1.00 11.63  ? 58  ILE B C   1 
ATOM   2494 O  O   . ILE B 2 76  ? 139.651 143.031 154.788 1.00 12.58  ? 58  ILE B O   1 
ATOM   2495 C  CB  . ILE B 2 76  ? 140.705 145.198 152.832 1.00 16.02  ? 58  ILE B CB  1 
ATOM   2496 C  CG1 . ILE B 2 76  ? 141.183 145.603 151.447 1.00 3.85   ? 58  ILE B CG1 1 
ATOM   2497 C  CG2 . ILE B 2 76  ? 141.100 146.246 153.842 1.00 4.68   ? 58  ILE B CG2 1 
ATOM   2498 C  CD1 . ILE B 2 76  ? 140.913 147.010 151.136 1.00 6.62   ? 58  ILE B CD1 1 
ATOM   2499 N  N   . TYR B 2 77  ? 141.707 143.512 155.587 1.00 11.61  ? 59  TYR B N   1 
ATOM   2500 C  CA  . TYR B 2 77  ? 141.364 143.124 156.950 1.00 7.16   ? 59  TYR B CA  1 
ATOM   2501 C  C   . TYR B 2 77  ? 141.180 144.282 157.914 1.00 10.82  ? 59  TYR B C   1 
ATOM   2502 O  O   . TYR B 2 77  ? 140.420 144.143 158.870 1.00 12.97  ? 59  TYR B O   1 
ATOM   2503 C  CB  . TYR B 2 77  ? 142.420 142.169 157.515 1.00 9.09   ? 59  TYR B CB  1 
ATOM   2504 C  CG  . TYR B 2 77  ? 141.920 140.754 157.696 1.00 15.46  ? 59  TYR B CG  1 
ATOM   2505 C  CD1 . TYR B 2 77  ? 141.823 139.883 156.627 1.00 19.36  ? 59  TYR B CD1 1 
ATOM   2506 C  CD2 . TYR B 2 77  ? 141.552 140.291 158.950 1.00 8.39   ? 59  TYR B CD2 1 
ATOM   2507 C  CE1 . TYR B 2 77  ? 141.365 138.599 156.801 1.00 6.91   ? 59  TYR B CE1 1 
ATOM   2508 C  CE2 . TYR B 2 77  ? 141.101 139.015 159.131 1.00 15.08  ? 59  TYR B CE2 1 
ATOM   2509 C  CZ  . TYR B 2 77  ? 141.010 138.170 158.055 1.00 16.76  ? 59  TYR B CZ  1 
ATOM   2510 O  OH  . TYR B 2 77  ? 140.553 136.889 158.235 1.00 22.08  ? 59  TYR B OH  1 
ATOM   2511 N  N   . ALA B 2 78  ? 141.835 145.417 157.697 1.00 13.55  ? 60  ALA B N   1 
ATOM   2512 C  CA  . ALA B 2 78  ? 141.716 146.520 158.633 1.00 9.44   ? 60  ALA B CA  1 
ATOM   2513 C  C   . ALA B 2 78  ? 141.948 147.843 157.922 1.00 5.26   ? 60  ALA B C   1 
ATOM   2514 O  O   . ALA B 2 78  ? 142.543 147.900 156.847 1.00 20.17  ? 60  ALA B O   1 
ATOM   2515 C  CB  . ALA B 2 78  ? 142.696 146.360 159.793 1.00 12.33  ? 60  ALA B CB  1 
ATOM   2516 N  N   . MET B 2 79  ? 141.441 148.908 158.537 1.00 0.00   ? 61  MET B N   1 
ATOM   2517 C  CA  . MET B 2 79  ? 141.710 150.277 158.130 1.00 0.00   ? 61  MET B CA  1 
ATOM   2518 C  C   . MET B 2 79  ? 141.612 151.157 159.361 1.00 8.15   ? 61  MET B C   1 
ATOM   2519 O  O   . MET B 2 79  ? 141.100 150.742 160.401 1.00 25.56  ? 61  MET B O   1 
ATOM   2520 C  CB  . MET B 2 79  ? 140.758 150.768 157.027 1.00 12.51  ? 61  MET B CB  1 
ATOM   2521 C  CG  . MET B 2 79  ? 139.287 150.932 157.410 1.00 11.71  ? 61  MET B CG  1 
ATOM   2522 S  SD  . MET B 2 79  ? 138.192 151.662 156.181 1.00 26.96  ? 61  MET B SD  1 
ATOM   2523 C  CE  . MET B 2 79  ? 138.572 153.396 156.314 1.00 14.34  ? 61  MET B CE  1 
ATOM   2524 N  N   . HIS B 2 80  ? 142.129 152.374 159.242 1.00 12.83  ? 62  HIS B N   1 
ATOM   2525 C  CA  . HIS B 2 80  ? 142.110 153.315 160.351 1.00 15.75  ? 62  HIS B CA  1 
ATOM   2526 C  C   . HIS B 2 80  ? 142.315 154.715 159.800 1.00 10.87  ? 62  HIS B C   1 
ATOM   2527 O  O   . HIS B 2 80  ? 143.177 154.923 158.950 1.00 20.43  ? 62  HIS B O   1 
ATOM   2528 C  CB  . HIS B 2 80  ? 143.188 152.966 161.381 1.00 19.92  ? 62  HIS B CB  1 
ATOM   2529 C  CG  . HIS B 2 80  ? 142.937 153.538 162.741 1.00 16.41  ? 62  HIS B CG  1 
ATOM   2530 N  ND1 . HIS B 2 80  ? 143.902 154.209 163.452 1.00 13.09  ? 62  HIS B ND1 1 
ATOM   2531 C  CD2 . HIS B 2 80  ? 141.831 153.542 163.516 1.00 24.86  ? 62  HIS B CD2 1 
ATOM   2532 C  CE1 . HIS B 2 80  ? 143.402 154.607 164.605 1.00 10.51  ? 62  HIS B CE1 1 
ATOM   2533 N  NE2 . HIS B 2 80  ? 142.146 154.214 164.669 1.00 13.40  ? 62  HIS B NE2 1 
ATOM   2534 N  N   . TRP B 2 81  ? 141.518 155.662 160.273 1.00 15.64  ? 63  TRP B N   1 
ATOM   2535 C  CA  . TRP B 2 81  ? 141.623 157.039 159.830 1.00 16.47  ? 63  TRP B CA  1 
ATOM   2536 C  C   . TRP B 2 81  ? 142.716 157.765 160.596 1.00 16.10  ? 63  TRP B C   1 
ATOM   2537 O  O   . TRP B 2 81  ? 143.004 157.456 161.752 1.00 14.67  ? 63  TRP B O   1 
ATOM   2538 C  CB  . TRP B 2 81  ? 140.303 157.782 160.040 1.00 20.92  ? 63  TRP B CB  1 
ATOM   2539 C  CG  . TRP B 2 81  ? 139.243 157.545 159.016 1.00 12.80  ? 63  TRP B CG  1 
ATOM   2540 C  CD1 . TRP B 2 81  ? 138.206 156.684 159.112 1.00 14.91  ? 63  TRP B CD1 1 
ATOM   2541 C  CD2 . TRP B 2 81  ? 139.097 158.208 157.759 1.00 22.03  ? 63  TRP B CD2 1 
ATOM   2542 N  NE1 . TRP B 2 81  ? 137.426 156.750 157.994 1.00 6.85   ? 63  TRP B NE1 1 
ATOM   2543 C  CE2 . TRP B 2 81  ? 137.953 157.682 157.143 1.00 27.25  ? 63  TRP B CE2 1 
ATOM   2544 C  CE3 . TRP B 2 81  ? 139.830 159.188 157.089 1.00 21.00  ? 63  TRP B CE3 1 
ATOM   2545 C  CZ2 . TRP B 2 81  ? 137.521 158.100 155.891 1.00 27.65  ? 63  TRP B CZ2 1 
ATOM   2546 C  CZ3 . TRP B 2 81  ? 139.400 159.599 155.851 1.00 21.38  ? 63  TRP B CZ3 1 
ATOM   2547 C  CH2 . TRP B 2 81  ? 138.257 159.058 155.264 1.00 19.91  ? 63  TRP B CH2 1 
ATOM   2548 N  N   . GLY B 2 82  ? 143.311 158.755 159.942 1.00 20.02  ? 64  GLY B N   1 
ATOM   2549 C  CA  . GLY B 2 82  ? 144.193 159.672 160.625 1.00 16.52  ? 64  GLY B CA  1 
ATOM   2550 C  C   . GLY B 2 82  ? 143.418 160.683 161.433 1.00 16.81  ? 64  GLY B C   1 
ATOM   2551 O  O   . GLY B 2 82  ? 142.207 160.827 161.304 1.00 22.09  ? 64  GLY B O   1 
ATOM   2552 N  N   . THR B 2 83  ? 144.136 161.398 162.295 1.00 15.04  ? 65  THR B N   1 
ATOM   2553 C  CA  . THR B 2 83  ? 143.486 162.393 163.136 1.00 19.53  ? 65  THR B CA  1 
ATOM   2554 C  C   . THR B 2 83  ? 143.156 163.665 162.363 1.00 25.46  ? 65  THR B C   1 
ATOM   2555 O  O   . THR B 2 83  ? 142.348 164.473 162.829 1.00 26.10  ? 65  THR B O   1 
ATOM   2556 C  CB  . THR B 2 83  ? 144.371 162.691 164.347 1.00 19.74  ? 65  THR B CB  1 
ATOM   2557 O  OG1 . THR B 2 83  ? 144.707 161.459 164.986 1.00 24.34  ? 65  THR B OG1 1 
ATOM   2558 C  CG2 . THR B 2 83  ? 143.650 163.545 165.357 1.00 19.90  ? 65  THR B CG2 1 
ATOM   2559 N  N   . ASP B 2 84  ? 143.737 163.849 161.182 1.00 23.28  ? 66  ASP B N   1 
ATOM   2560 C  CA  . ASP B 2 84  ? 143.395 164.980 160.335 1.00 17.87  ? 66  ASP B CA  1 
ATOM   2561 C  C   . ASP B 2 84  ? 142.183 164.712 159.457 1.00 21.14  ? 66  ASP B C   1 
ATOM   2562 O  O   . ASP B 2 84  ? 141.772 165.607 158.712 1.00 26.62  ? 66  ASP B O   1 
ATOM   2563 C  CB  . ASP B 2 84  ? 144.590 165.375 159.465 1.00 19.70  ? 66  ASP B CB  1 
ATOM   2564 C  CG  . ASP B 2 84  ? 145.045 164.262 158.541 1.00 25.27  ? 66  ASP B CG  1 
ATOM   2565 O  OD1 . ASP B 2 84  ? 144.453 163.170 158.563 1.00 24.10  ? 66  ASP B OD1 1 
ATOM   2566 O  OD2 . ASP B 2 84  ? 146.011 164.484 157.786 1.00 30.68  ? 66  ASP B OD2 1 
ATOM   2567 N  N   . SER B 2 85  ? 141.619 163.506 159.517 1.00 18.23  ? 67  SER B N   1 
ATOM   2568 C  CA  . SER B 2 85  ? 140.399 163.126 158.816 1.00 16.57  ? 67  SER B CA  1 
ATOM   2569 C  C   . SER B 2 85  ? 140.550 163.151 157.302 1.00 21.92  ? 67  SER B C   1 
ATOM   2570 O  O   . SER B 2 85  ? 139.553 163.200 156.583 1.00 26.84  ? 67  SER B O   1 
ATOM   2571 C  CB  . SER B 2 85  ? 139.226 164.010 159.240 1.00 21.98  ? 67  SER B CB  1 
ATOM   2572 O  OG  . SER B 2 85  ? 138.913 163.809 160.603 1.00 24.42  ? 67  SER B OG  1 
ATOM   2573 N  N   . ARG B 2 86  ? 141.775 163.110 156.797 1.00 29.64  ? 68  ARG B N   1 
ATOM   2574 C  CA  . ARG B 2 86  ? 142.028 163.102 155.362 1.00 21.18  ? 68  ARG B CA  1 
ATOM   2575 C  C   . ARG B 2 86  ? 142.800 161.882 154.890 1.00 19.92  ? 68  ARG B C   1 
ATOM   2576 O  O   . ARG B 2 86  ? 142.446 161.301 153.864 1.00 14.06  ? 68  ARG B O   1 
ATOM   2577 C  CB  . ARG B 2 86  ? 142.790 164.364 154.957 1.00 14.27  ? 68  ARG B CB  1 
ATOM   2578 C  CG  . ARG B 2 86  ? 143.220 164.361 153.524 1.00 19.09  ? 68  ARG B CG  1 
ATOM   2579 C  CD  . ARG B 2 86  ? 144.008 165.595 153.187 1.00 24.83  ? 68  ARG B CD  1 
ATOM   2580 N  NE  . ARG B 2 86  ? 144.236 165.701 151.752 1.00 23.43  ? 68  ARG B NE  1 
ATOM   2581 C  CZ  . ARG B 2 86  ? 144.301 166.846 151.089 1.00 23.18  ? 68  ARG B CZ  1 
ATOM   2582 N  NH1 . ARG B 2 86  ? 144.170 168.007 151.706 1.00 22.20  ? 68  ARG B NH1 1 
ATOM   2583 N  NH2 . ARG B 2 86  ? 144.500 166.824 149.776 1.00 22.89  ? 68  ARG B NH2 1 
ATOM   2584 N  N   . LEU B 2 87  ? 143.840 161.474 155.617 1.00 18.66  ? 69  LEU B N   1 
ATOM   2585 C  CA  . LEU B 2 87  ? 144.670 160.334 155.258 1.00 13.17  ? 69  LEU B CA  1 
ATOM   2586 C  C   . LEU B 2 87  ? 144.224 159.097 156.022 1.00 15.38  ? 69  LEU B C   1 
ATOM   2587 O  O   . LEU B 2 87  ? 143.724 159.191 157.143 1.00 16.29  ? 69  LEU B O   1 
ATOM   2588 C  CB  . LEU B 2 87  ? 146.143 160.608 155.556 1.00 13.60  ? 69  LEU B CB  1 
ATOM   2589 C  CG  . LEU B 2 87  ? 146.883 161.733 154.837 1.00 17.69  ? 69  LEU B CG  1 
ATOM   2590 C  CD1 . LEU B 2 87  ? 148.239 161.930 155.460 1.00 17.44  ? 69  LEU B CD1 1 
ATOM   2591 C  CD2 . LEU B 2 87  ? 147.027 161.427 153.375 1.00 15.82  ? 69  LEU B CD2 1 
ATOM   2592 N  N   . LEU B 2 88  ? 144.408 157.932 155.405 1.00 17.58  ? 70  LEU B N   1 
ATOM   2593 C  CA  . LEU B 2 88  ? 143.969 156.694 156.038 1.00 8.45   ? 70  LEU B CA  1 
ATOM   2594 C  C   . LEU B 2 88  ? 144.862 155.536 155.612 1.00 8.78   ? 70  LEU B C   1 
ATOM   2595 O  O   . LEU B 2 88  ? 145.350 155.495 154.487 1.00 20.18  ? 70  LEU B O   1 
ATOM   2596 C  CB  . LEU B 2 88  ? 142.496 156.406 155.712 1.00 12.59  ? 70  LEU B CB  1 
ATOM   2597 C  CG  . LEU B 2 88  ? 142.042 156.180 154.273 1.00 18.72  ? 70  LEU B CG  1 
ATOM   2598 C  CD1 . LEU B 2 88  ? 142.347 154.772 153.827 1.00 11.91  ? 70  LEU B CD1 1 
ATOM   2599 C  CD2 . LEU B 2 88  ? 140.574 156.475 154.120 1.00 16.18  ? 70  LEU B CD2 1 
ATOM   2600 N  N   . VAL B 2 89  ? 145.061 154.588 156.522 1.00 10.53  ? 71  VAL B N   1 
ATOM   2601 C  CA  . VAL B 2 89  ? 145.903 153.420 156.282 1.00 9.98   ? 71  VAL B CA  1 
ATOM   2602 C  C   . VAL B 2 89  ? 145.013 152.193 156.141 1.00 6.05   ? 71  VAL B C   1 
ATOM   2603 O  O   . VAL B 2 89  ? 143.946 152.109 156.749 1.00 23.96  ? 71  VAL B O   1 
ATOM   2604 C  CB  . VAL B 2 89  ? 146.942 153.242 157.414 1.00 16.78  ? 71  VAL B CB  1 
ATOM   2605 C  CG1 . VAL B 2 89  ? 146.262 152.983 158.739 1.00 11.03  ? 71  VAL B CG1 1 
ATOM   2606 C  CG2 . VAL B 2 89  ? 147.929 152.145 157.088 1.00 11.07  ? 71  VAL B CG2 1 
ATOM   2607 N  N   . SER B 2 90  ? 145.435 151.250 155.301 1.00 0.00   ? 72  SER B N   1 
ATOM   2608 C  CA  . SER B 2 90  ? 144.684 150.016 155.118 1.00 2.76   ? 72  SER B CA  1 
ATOM   2609 C  C   . SER B 2 90  ? 145.638 148.845 154.936 1.00 6.93   ? 72  SER B C   1 
ATOM   2610 O  O   . SER B 2 90  ? 146.732 148.991 154.387 1.00 13.36  ? 72  SER B O   1 
ATOM   2611 C  CB  . SER B 2 90  ? 143.725 150.106 153.931 1.00 6.73   ? 72  SER B CB  1 
ATOM   2612 O  OG  . SER B 2 90  ? 144.426 150.267 152.715 1.00 22.46  ? 72  SER B OG  1 
ATOM   2613 N  N   . ALA B 2 91  ? 145.195 147.676 155.399 1.00 2.80   ? 73  ALA B N   1 
ATOM   2614 C  CA  . ALA B 2 91  ? 146.001 146.464 155.455 1.00 10.48  ? 73  ALA B CA  1 
ATOM   2615 C  C   . ALA B 2 91  ? 145.345 145.358 154.645 1.00 9.62   ? 73  ALA B C   1 
ATOM   2616 O  O   . ALA B 2 91  ? 144.149 145.084 154.809 1.00 15.65  ? 73  ALA B O   1 
ATOM   2617 C  CB  . ALA B 2 91  ? 146.189 145.994 156.896 1.00 5.65   ? 73  ALA B CB  1 
ATOM   2618 N  N   . SER B 2 92  ? 146.131 144.712 153.789 1.00 2.98   ? 74  SER B N   1 
ATOM   2619 C  CA  . SER B 2 92  ? 145.634 143.616 152.981 1.00 2.52   ? 74  SER B CA  1 
ATOM   2620 C  C   . SER B 2 92  ? 146.597 142.443 153.033 1.00 14.36  ? 74  SER B C   1 
ATOM   2621 O  O   . SER B 2 92  ? 147.821 142.605 153.127 1.00 12.54  ? 74  SER B O   1 
ATOM   2622 C  CB  . SER B 2 92  ? 145.410 144.030 151.532 1.00 11.86  ? 74  SER B CB  1 
ATOM   2623 O  OG  . SER B 2 92  ? 144.645 143.062 150.842 1.00 12.32  ? 74  SER B OG  1 
ATOM   2624 N  N   . GLN B 2 93  ? 146.006 141.257 152.919 1.00 14.01  ? 75  GLN B N   1 
ATOM   2625 C  CA  . GLN B 2 93  ? 146.655 139.978 153.146 1.00 13.80  ? 75  GLN B CA  1 
ATOM   2626 C  C   . GLN B 2 93  ? 147.467 139.491 151.957 1.00 15.52  ? 75  GLN B C   1 
ATOM   2627 O  O   . GLN B 2 93  ? 147.953 138.358 151.981 1.00 17.06  ? 75  GLN B O   1 
ATOM   2628 C  CB  . GLN B 2 93  ? 145.608 138.933 153.522 1.00 14.59  ? 75  GLN B CB  1 
ATOM   2629 C  CG  . GLN B 2 93  ? 145.118 139.059 154.946 1.00 18.53  ? 75  GLN B CG  1 
ATOM   2630 C  CD  . GLN B 2 93  ? 144.827 137.727 155.566 1.00 14.86  ? 75  GLN B CD  1 
ATOM   2631 O  OE1 . GLN B 2 93  ? 144.723 136.727 154.871 1.00 21.22  ? 75  GLN B OE1 1 
ATOM   2632 N  NE2 . GLN B 2 93  ? 144.694 137.700 156.880 1.00 8.98   ? 75  GLN B NE2 1 
ATOM   2633 N  N   . ASP B 2 94  ? 147.608 140.303 150.914 1.00 13.27  ? 76  ASP B N   1 
ATOM   2634 C  CA  . ASP B 2 94  ? 148.675 140.089 149.951 1.00 6.30   ? 76  ASP B CA  1 
ATOM   2635 C  C   . ASP B 2 94  ? 150.023 140.506 150.506 1.00 11.05  ? 76  ASP B C   1 
ATOM   2636 O  O   . ASP B 2 94  ? 151.047 140.254 149.866 1.00 21.29  ? 76  ASP B O   1 
ATOM   2637 C  CB  . ASP B 2 94  ? 148.392 140.844 148.651 1.00 11.24  ? 76  ASP B CB  1 
ATOM   2638 C  CG  . ASP B 2 94  ? 147.913 142.258 148.884 1.00 19.54  ? 76  ASP B CG  1 
ATOM   2639 O  OD1 . ASP B 2 94  ? 146.726 142.434 149.198 1.00 28.93  ? 76  ASP B OD1 1 
ATOM   2640 O  OD2 . ASP B 2 94  ? 148.711 143.199 148.739 1.00 17.87  ? 76  ASP B OD2 1 
ATOM   2641 N  N   . GLY B 2 95  ? 150.036 141.123 151.681 1.00 7.25   ? 77  GLY B N   1 
ATOM   2642 C  CA  . GLY B 2 95  ? 151.238 141.616 152.297 1.00 3.91   ? 77  GLY B CA  1 
ATOM   2643 C  C   . GLY B 2 95  ? 151.447 143.102 152.170 1.00 10.48  ? 77  GLY B C   1 
ATOM   2644 O  O   . GLY B 2 95  ? 152.599 143.537 152.098 1.00 12.48  ? 77  GLY B O   1 
ATOM   2645 N  N   . LYS B 2 96  ? 150.380 143.900 152.156 1.00 13.84  ? 78  LYS B N   1 
ATOM   2646 C  CA  . LYS B 2 96  ? 150.504 145.301 151.780 1.00 5.86   ? 78  LYS B CA  1 
ATOM   2647 C  C   . LYS B 2 96  ? 149.863 146.211 152.813 1.00 3.72   ? 78  LYS B C   1 
ATOM   2648 O  O   . LYS B 2 96  ? 148.803 145.898 153.363 1.00 13.44  ? 78  LYS B O   1 
ATOM   2649 C  CB  . LYS B 2 96  ? 149.868 145.553 150.407 1.00 14.36  ? 78  LYS B CB  1 
ATOM   2650 C  CG  . LYS B 2 96  ? 150.479 146.698 149.613 1.00 14.32  ? 78  LYS B CG  1 
ATOM   2651 C  CD  . LYS B 2 96  ? 151.988 146.644 149.611 1.00 17.66  ? 78  LYS B CD  1 
ATOM   2652 C  CE  . LYS B 2 96  ? 152.510 145.696 148.566 1.00 14.19  ? 78  LYS B CE  1 
ATOM   2653 N  NZ  . LYS B 2 96  ? 153.911 146.026 148.220 1.00 15.84  ? 78  LYS B NZ  1 
ATOM   2654 N  N   . LEU B 2 97  ? 150.516 147.349 153.058 1.00 8.06   ? 79  LEU B N   1 
ATOM   2655 C  CA  . LEU B 2 97  ? 149.990 148.424 153.894 1.00 9.03   ? 79  LEU B CA  1 
ATOM   2656 C  C   . LEU B 2 97  ? 150.007 149.701 153.065 1.00 13.22  ? 79  LEU B C   1 
ATOM   2657 O  O   . LEU B 2 97  ? 151.076 150.245 152.789 1.00 7.78   ? 79  LEU B O   1 
ATOM   2658 C  CB  . LEU B 2 97  ? 150.836 148.579 155.157 1.00 12.89  ? 79  LEU B CB  1 
ATOM   2659 C  CG  . LEU B 2 97  ? 150.229 148.870 156.524 1.00 12.77  ? 79  LEU B CG  1 
ATOM   2660 C  CD1 . LEU B 2 97  ? 149.347 147.739 156.978 1.00 14.12  ? 79  LEU B CD1 1 
ATOM   2661 C  CD2 . LEU B 2 97  ? 151.348 149.084 157.507 1.00 9.63   ? 79  LEU B CD2 1 
ATOM   2662 N  N   . ILE B 2 98  ? 148.836 150.190 152.668 1.00 14.14  ? 80  ILE B N   1 
ATOM   2663 C  CA  . ILE B 2 98  ? 148.743 151.335 151.764 1.00 8.76   ? 80  ILE B CA  1 
ATOM   2664 C  C   . ILE B 2 98  ? 148.171 152.524 152.518 1.00 6.49   ? 80  ILE B C   1 
ATOM   2665 O  O   . ILE B 2 98  ? 147.171 152.390 153.231 1.00 17.65  ? 80  ILE B O   1 
ATOM   2666 C  CB  . ILE B 2 98  ? 147.900 151.023 150.515 1.00 7.29   ? 80  ILE B CB  1 
ATOM   2667 C  CG1 . ILE B 2 98  ? 148.517 149.881 149.713 1.00 10.64  ? 80  ILE B CG1 1 
ATOM   2668 C  CG2 . ILE B 2 98  ? 147.835 152.229 149.617 1.00 9.11   ? 80  ILE B CG2 1 
ATOM   2669 C  CD1 . ILE B 2 98  ? 147.900 149.691 148.362 1.00 5.36   ? 80  ILE B CD1 1 
ATOM   2670 N  N   . ILE B 2 99  ? 148.803 153.686 152.355 1.00 7.35   ? 81  ILE B N   1 
ATOM   2671 C  CA  . ILE B 2 99  ? 148.350 154.943 152.944 1.00 6.37   ? 81  ILE B CA  1 
ATOM   2672 C  C   . ILE B 2 99  ? 147.776 155.804 151.829 1.00 12.44  ? 81  ILE B C   1 
ATOM   2673 O  O   . ILE B 2 99  ? 148.465 156.098 150.847 1.00 13.72  ? 81  ILE B O   1 
ATOM   2674 C  CB  . ILE B 2 99  ? 149.490 155.669 153.670 1.00 7.17   ? 81  ILE B CB  1 
ATOM   2675 C  CG1 . ILE B 2 99  ? 150.043 154.796 154.791 1.00 8.66   ? 81  ILE B CG1 1 
ATOM   2676 C  CG2 . ILE B 2 99  ? 149.015 156.995 154.210 1.00 4.80   ? 81  ILE B CG2 1 
ATOM   2677 C  CD1 . ILE B 2 99  ? 151.149 155.428 155.550 1.00 9.15   ? 81  ILE B CD1 1 
ATOM   2678 N  N   . TRP B 2 100 ? 146.518 156.211 151.978 1.00 15.94  ? 82  TRP B N   1 
ATOM   2679 C  CA  . TRP B 2 100 ? 145.786 156.932 150.950 1.00 8.29   ? 82  TRP B CA  1 
ATOM   2680 C  C   . TRP B 2 100 ? 145.433 158.337 151.404 1.00 14.83  ? 82  TRP B C   1 
ATOM   2681 O  O   . TRP B 2 100 ? 145.162 158.580 152.585 1.00 27.02  ? 82  TRP B O   1 
ATOM   2682 C  CB  . TRP B 2 100 ? 144.472 156.254 150.572 1.00 2.76   ? 82  TRP B CB  1 
ATOM   2683 C  CG  . TRP B 2 100 ? 144.457 154.780 150.536 1.00 13.56  ? 82  TRP B CG  1 
ATOM   2684 C  CD1 . TRP B 2 100 ? 144.438 153.934 151.598 1.00 7.98   ? 82  TRP B CD1 1 
ATOM   2685 C  CD2 . TRP B 2 100 ? 144.387 153.963 149.368 1.00 16.39  ? 82  TRP B CD2 1 
ATOM   2686 N  NE1 . TRP B 2 100 ? 144.390 152.636 151.166 1.00 5.09   ? 82  TRP B NE1 1 
ATOM   2687 C  CE2 . TRP B 2 100 ? 144.356 152.626 149.798 1.00 14.99  ? 82  TRP B CE2 1 
ATOM   2688 C  CE3 . TRP B 2 100 ? 144.359 154.231 147.998 1.00 4.27   ? 82  TRP B CE3 1 
ATOM   2689 C  CZ2 . TRP B 2 100 ? 144.301 151.562 148.910 1.00 4.76   ? 82  TRP B CZ2 1 
ATOM   2690 C  CZ3 . TRP B 2 100 ? 144.304 153.176 147.123 1.00 11.62  ? 82  TRP B CZ3 1 
ATOM   2691 C  CH2 . TRP B 2 100 ? 144.277 151.857 147.580 1.00 8.30   ? 82  TRP B CH2 1 
ATOM   2692 N  N   . ASP B 2 101 ? 145.419 159.247 150.436 1.00 17.93  ? 83  ASP B N   1 
ATOM   2693 C  CA  . ASP B 2 101 ? 144.725 160.520 150.552 1.00 16.94  ? 83  ASP B CA  1 
ATOM   2694 C  C   . ASP B 2 101 ? 143.298 160.317 150.061 1.00 21.23  ? 83  ASP B C   1 
ATOM   2695 O  O   . ASP B 2 101 ? 143.081 159.989 148.893 1.00 29.23  ? 83  ASP B O   1 
ATOM   2696 C  CB  . ASP B 2 101 ? 145.428 161.598 149.736 1.00 22.62  ? 83  ASP B CB  1 
ATOM   2697 C  CG  . ASP B 2 101 ? 144.972 162.987 150.097 1.00 30.11  ? 83  ASP B CG  1 
ATOM   2698 O  OD1 . ASP B 2 101 ? 143.792 163.161 150.450 1.00 24.78  ? 83  ASP B OD1 1 
ATOM   2699 O  OD2 . ASP B 2 101 ? 145.799 163.914 150.031 1.00 37.78  ? 83  ASP B OD2 1 
ATOM   2700 N  N   . SER B 2 102 ? 142.331 160.496 150.955 1.00 19.67  ? 84  SER B N   1 
ATOM   2701 C  CA  . SER B 2 102 ? 140.948 160.188 150.620 1.00 14.80  ? 84  SER B CA  1 
ATOM   2702 C  C   . SER B 2 102 ? 140.308 161.254 149.740 1.00 25.89  ? 84  SER B C   1 
ATOM   2703 O  O   . SER B 2 102 ? 139.400 160.939 148.965 1.00 28.97  ? 84  SER B O   1 
ATOM   2704 C  CB  . SER B 2 102 ? 140.147 159.990 151.902 1.00 18.67  ? 84  SER B CB  1 
ATOM   2705 O  OG  . SER B 2 102 ? 140.421 161.014 152.831 1.00 25.63  ? 84  SER B OG  1 
ATOM   2706 N  N   . TYR B 2 103 ? 140.755 162.508 149.841 1.00 29.02  ? 85  TYR B N   1 
ATOM   2707 C  CA  . TYR B 2 103 ? 140.192 163.561 149.003 1.00 16.74  ? 85  TYR B CA  1 
ATOM   2708 C  C   . TYR B 2 103 ? 140.493 163.310 147.532 1.00 26.33  ? 85  TYR B C   1 
ATOM   2709 O  O   . TYR B 2 103 ? 139.585 163.285 146.695 1.00 34.74  ? 85  TYR B O   1 
ATOM   2710 C  CB  . TYR B 2 103 ? 140.742 164.922 149.421 1.00 21.27  ? 85  TYR B CB  1 
ATOM   2711 C  CG  . TYR B 2 103 ? 140.262 165.451 150.750 1.00 25.13  ? 85  TYR B CG  1 
ATOM   2712 C  CD1 . TYR B 2 103 ? 139.492 164.684 151.597 1.00 18.85  ? 85  TYR B CD1 1 
ATOM   2713 C  CD2 . TYR B 2 103 ? 140.594 166.730 151.156 1.00 25.02  ? 85  TYR B CD2 1 
ATOM   2714 C  CE1 . TYR B 2 103 ? 139.071 165.174 152.804 1.00 22.71  ? 85  TYR B CE1 1 
ATOM   2715 C  CE2 . TYR B 2 103 ? 140.176 167.226 152.359 1.00 20.16  ? 85  TYR B CE2 1 
ATOM   2716 C  CZ  . TYR B 2 103 ? 139.414 166.446 153.178 1.00 22.21  ? 85  TYR B CZ  1 
ATOM   2717 O  OH  . TYR B 2 103 ? 138.996 166.943 154.385 1.00 33.76  ? 85  TYR B OH  1 
ATOM   2718 N  N   . THR B 2 104 ? 141.767 163.103 147.203 1.00 30.27  ? 86  THR B N   1 
ATOM   2719 C  CA  . THR B 2 104 ? 142.234 163.009 145.828 1.00 22.04  ? 86  THR B CA  1 
ATOM   2720 C  C   . THR B 2 104 ? 142.477 161.581 145.356 1.00 19.10  ? 86  THR B C   1 
ATOM   2721 O  O   . THR B 2 104 ? 142.891 161.393 144.212 1.00 24.82  ? 86  THR B O   1 
ATOM   2722 C  CB  . THR B 2 104 ? 143.521 163.814 145.662 1.00 23.89  ? 86  THR B CB  1 
ATOM   2723 O  OG1 . THR B 2 104 ? 144.616 163.072 146.199 1.00 24.49  ? 86  THR B OG1 1 
ATOM   2724 C  CG2 . THR B 2 104 ? 143.422 165.127 146.396 1.00 28.96  ? 86  THR B CG2 1 
ATOM   2725 N  N   . THR B 2 105 ? 142.250 160.580 146.206 1.00 27.70  ? 87  THR B N   1 
ATOM   2726 C  CA  . THR B 2 105 ? 142.398 159.163 145.869 1.00 24.03  ? 87  THR B CA  1 
ATOM   2727 C  C   . THR B 2 105 ? 143.843 158.785 145.545 1.00 25.70  ? 87  THR B C   1 
ATOM   2728 O  O   . THR B 2 105 ? 144.097 157.734 144.952 1.00 30.46  ? 87  THR B O   1 
ATOM   2729 C  CB  . THR B 2 105 ? 141.469 158.771 144.715 1.00 25.37  ? 87  THR B CB  1 
ATOM   2730 O  OG1 . THR B 2 105 ? 140.257 159.523 144.815 1.00 33.58  ? 87  THR B OG1 1 
ATOM   2731 C  CG2 . THR B 2 105 ? 141.118 157.303 144.778 1.00 24.74  ? 87  THR B CG2 1 
ATOM   2732 N  N   . ASN B 2 106 ? 144.806 159.611 145.937 1.00 21.90  ? 88  ASN B N   1 
ATOM   2733 C  CA  . ASN B 2 106 ? 146.203 159.313 145.673 1.00 21.08  ? 88  ASN B CA  1 
ATOM   2734 C  C   . ASN B 2 106 ? 146.693 158.222 146.619 1.00 24.01  ? 88  ASN B C   1 
ATOM   2735 O  O   . ASN B 2 106 ? 145.985 157.779 147.521 1.00 34.46  ? 88  ASN B O   1 
ATOM   2736 C  CB  . ASN B 2 106 ? 147.050 160.572 145.819 1.00 27.25  ? 88  ASN B CB  1 
ATOM   2737 C  CG  . ASN B 2 106 ? 147.051 161.420 144.572 1.00 31.48  ? 88  ASN B CG  1 
ATOM   2738 O  OD1 . ASN B 2 106 ? 146.973 160.907 143.460 1.00 31.85  ? 88  ASN B OD1 1 
ATOM   2739 N  ND2 . ASN B 2 106 ? 147.131 162.727 144.748 1.00 31.63  ? 88  ASN B ND2 1 
ATOM   2740 N  N   . LYS B 2 107 ? 147.925 157.776 146.397 1.00 24.36  ? 89  LYS B N   1 
ATOM   2741 C  CA  . LYS B 2 107 ? 148.624 156.872 147.298 1.00 20.32  ? 89  LYS B CA  1 
ATOM   2742 C  C   . LYS B 2 107 ? 149.856 157.587 147.820 1.00 21.85  ? 89  LYS B C   1 
ATOM   2743 O  O   . LYS B 2 107 ? 150.638 158.123 147.033 1.00 33.55  ? 89  LYS B O   1 
ATOM   2744 C  CB  . LYS B 2 107 ? 149.036 155.581 146.596 1.00 17.57  ? 89  LYS B CB  1 
ATOM   2745 C  CG  . LYS B 2 107 ? 147.911 154.616 146.304 1.00 18.91  ? 89  LYS B CG  1 
ATOM   2746 C  CD  . LYS B 2 107 ? 148.456 153.357 145.668 1.00 18.41  ? 89  LYS B CD  1 
ATOM   2747 C  CE  . LYS B 2 107 ? 147.382 152.575 144.960 1.00 20.32  ? 89  LYS B CE  1 
ATOM   2748 N  NZ  . LYS B 2 107 ? 146.659 153.407 143.978 1.00 28.51  ? 89  LYS B NZ  1 
ATOM   2749 N  N   . VAL B 2 108 ? 150.030 157.602 149.135 1.00 15.62  ? 90  VAL B N   1 
ATOM   2750 C  CA  . VAL B 2 108 ? 151.161 158.279 149.759 1.00 12.14  ? 90  VAL B CA  1 
ATOM   2751 C  C   . VAL B 2 108 ? 152.309 157.318 150.023 1.00 14.26  ? 90  VAL B C   1 
ATOM   2752 O  O   . VAL B 2 108 ? 153.455 157.608 149.689 1.00 23.98  ? 90  VAL B O   1 
ATOM   2753 C  CB  . VAL B 2 108 ? 150.711 158.991 151.053 1.00 12.92  ? 90  VAL B CB  1 
ATOM   2754 C  CG1 . VAL B 2 108 ? 151.809 159.880 151.565 1.00 12.69  ? 90  VAL B CG1 1 
ATOM   2755 C  CG2 . VAL B 2 108 ? 149.467 159.800 150.794 1.00 10.68  ? 90  VAL B CG2 1 
ATOM   2756 N  N   . HIS B 2 109 ? 152.016 156.166 150.621 1.00 14.61  ? 91  HIS B N   1 
ATOM   2757 C  CA  . HIS B 2 109 ? 153.000 155.128 150.881 1.00 3.19   ? 91  HIS B CA  1 
ATOM   2758 C  C   . HIS B 2 109 ? 152.397 153.777 150.542 1.00 7.45   ? 91  HIS B C   1 
ATOM   2759 O  O   . HIS B 2 109 ? 151.184 153.584 150.632 1.00 13.38  ? 91  HIS B O   1 
ATOM   2760 C  CB  . HIS B 2 109 ? 153.453 155.094 152.345 1.00 14.22  ? 91  HIS B CB  1 
ATOM   2761 C  CG  . HIS B 2 109 ? 154.168 156.324 152.804 1.00 14.10  ? 91  HIS B CG  1 
ATOM   2762 N  ND1 . HIS B 2 109 ? 153.643 157.179 153.747 1.00 10.90  ? 91  HIS B ND1 1 
ATOM   2763 C  CD2 . HIS B 2 109 ? 155.383 156.822 152.483 1.00 13.45  ? 91  HIS B CD2 1 
ATOM   2764 C  CE1 . HIS B 2 109 ? 154.494 158.162 153.971 1.00 12.17  ? 91  HIS B CE1 1 
ATOM   2765 N  NE2 . HIS B 2 109 ? 155.559 157.968 153.218 1.00 14.32  ? 91  HIS B NE2 1 
ATOM   2766 N  N   . ALA B 2 110 ? 153.263 152.838 150.174 1.00 20.48  ? 92  ALA B N   1 
ATOM   2767 C  CA  . ALA B 2 110 ? 152.907 151.426 150.054 1.00 16.19  ? 92  ALA B CA  1 
ATOM   2768 C  C   . ALA B 2 110 ? 154.037 150.628 150.687 1.00 20.78  ? 92  ALA B C   1 
ATOM   2769 O  O   . ALA B 2 110 ? 155.149 150.599 150.155 1.00 18.92  ? 92  ALA B O   1 
ATOM   2770 C  CB  . ALA B 2 110 ? 152.689 151.017 148.600 1.00 9.15   ? 92  ALA B CB  1 
ATOM   2771 N  N   . ILE B 2 111 ? 153.760 150.002 151.823 1.00 16.98  ? 93  ILE B N   1 
ATOM   2772 C  CA  . ILE B 2 111 ? 154.754 149.344 152.663 1.00 17.16  ? 93  ILE B CA  1 
ATOM   2773 C  C   . ILE B 2 111 ? 154.577 147.836 152.525 1.00 11.81  ? 93  ILE B C   1 
ATOM   2774 O  O   . ILE B 2 111 ? 153.471 147.324 152.755 1.00 2.58   ? 93  ILE B O   1 
ATOM   2775 C  CB  . ILE B 2 111 ? 154.631 149.784 154.131 1.00 15.36  ? 93  ILE B CB  1 
ATOM   2776 C  CG1 . ILE B 2 111 ? 154.337 151.279 154.208 1.00 11.22  ? 93  ILE B CG1 1 
ATOM   2777 C  CG2 . ILE B 2 111 ? 155.894 149.463 154.892 1.00 12.89  ? 93  ILE B CG2 1 
ATOM   2778 C  CD1 . ILE B 2 111 ? 154.002 151.760 155.576 1.00 11.86  ? 93  ILE B CD1 1 
ATOM   2779 N  N   . PRO B 2 112 ? 155.613 147.099 152.129 1.00 18.78  ? 94  PRO B N   1 
ATOM   2780 C  CA  . PRO B 2 112 ? 155.550 145.639 152.118 1.00 19.30  ? 94  PRO B CA  1 
ATOM   2781 C  C   . PRO B 2 112 ? 155.941 145.036 153.457 1.00 24.23  ? 94  PRO B C   1 
ATOM   2782 O  O   . PRO B 2 112 ? 156.828 145.520 154.162 1.00 23.72  ? 94  PRO B O   1 
ATOM   2783 C  CB  . PRO B 2 112 ? 156.575 145.273 151.039 1.00 12.78  ? 94  PRO B CB  1 
ATOM   2784 C  CG  . PRO B 2 112 ? 157.596 146.326 151.167 1.00 8.75   ? 94  PRO B CG  1 
ATOM   2785 C  CD  . PRO B 2 112 ? 156.870 147.589 151.539 1.00 14.56  ? 94  PRO B CD  1 
ATOM   2786 N  N   . LEU B 2 113 ? 155.266 143.945 153.795 1.00 12.25  ? 95  LEU B N   1 
ATOM   2787 C  CA  . LEU B 2 113 ? 155.401 143.312 155.093 1.00 9.54   ? 95  LEU B CA  1 
ATOM   2788 C  C   . LEU B 2 113 ? 156.136 141.985 154.962 1.00 18.44  ? 95  LEU B C   1 
ATOM   2789 O  O   . LEU B 2 113 ? 156.033 141.299 153.944 1.00 24.52  ? 95  LEU B O   1 
ATOM   2790 C  CB  . LEU B 2 113 ? 154.027 143.086 155.728 1.00 10.60  ? 95  LEU B CB  1 
ATOM   2791 C  CG  . LEU B 2 113 ? 153.000 144.209 155.625 1.00 2.56   ? 95  LEU B CG  1 
ATOM   2792 C  CD1 . LEU B 2 113 ? 151.667 143.739 156.132 1.00 1.81   ? 95  LEU B CD1 1 
ATOM   2793 C  CD2 . LEU B 2 113 ? 153.450 145.411 156.400 1.00 7.57   ? 95  LEU B CD2 1 
ATOM   2794 N  N   . ARG B 2 114 ? 156.882 141.630 156.011 1.00 13.26  ? 96  ARG B N   1 
ATOM   2795 C  CA  . ARG B 2 114 ? 157.571 140.344 156.026 1.00 13.28  ? 96  ARG B CA  1 
ATOM   2796 C  C   . ARG B 2 114 ? 156.596 139.177 156.079 1.00 18.43  ? 96  ARG B C   1 
ATOM   2797 O  O   . ARG B 2 114 ? 156.894 138.101 155.550 1.00 27.00  ? 96  ARG B O   1 
ATOM   2798 C  CB  . ARG B 2 114 ? 158.527 140.267 157.211 1.00 11.43  ? 96  ARG B CB  1 
ATOM   2799 C  CG  . ARG B 2 114 ? 159.719 141.182 157.107 1.00 17.00  ? 96  ARG B CG  1 
ATOM   2800 C  CD  . ARG B 2 114 ? 160.590 141.110 158.350 1.00 20.69  ? 96  ARG B CD  1 
ATOM   2801 N  NE  . ARG B 2 114 ? 161.188 139.794 158.546 1.00 30.78  ? 96  ARG B NE  1 
ATOM   2802 C  CZ  . ARG B 2 114 ? 162.307 139.378 157.968 1.00 29.34  ? 96  ARG B CZ  1 
ATOM   2803 N  NH1 . ARG B 2 114 ? 163.001 140.161 157.159 1.00 22.51  ? 96  ARG B NH1 1 
ATOM   2804 N  NH2 . ARG B 2 114 ? 162.748 138.149 158.218 1.00 25.05  ? 96  ARG B NH2 1 
ATOM   2805 N  N   . SER B 2 115 ? 155.443 139.358 156.716 1.00 9.09   ? 97  SER B N   1 
ATOM   2806 C  CA  . SER B 2 115 ? 154.435 138.316 156.833 1.00 8.62   ? 97  SER B CA  1 
ATOM   2807 C  C   . SER B 2 115 ? 153.173 138.759 156.111 1.00 15.02  ? 97  SER B C   1 
ATOM   2808 O  O   . SER B 2 115 ? 152.695 139.876 156.318 1.00 14.77  ? 97  SER B O   1 
ATOM   2809 C  CB  . SER B 2 115 ? 154.136 138.009 158.297 1.00 13.91  ? 97  SER B CB  1 
ATOM   2810 O  OG  . SER B 2 115 ? 153.636 136.692 158.452 1.00 26.40  ? 97  SER B OG  1 
ATOM   2811 N  N   . SER B 2 116 ? 152.636 137.878 155.271 1.00 11.77  ? 98  SER B N   1 
ATOM   2812 C  CA  . SER B 2 116 ? 151.498 138.202 154.423 1.00 3.29   ? 98  SER B CA  1 
ATOM   2813 C  C   . SER B 2 116 ? 150.160 138.063 155.128 1.00 6.45   ? 98  SER B C   1 
ATOM   2814 O  O   . SER B 2 116 ? 149.132 138.393 154.533 1.00 12.42  ? 98  SER B O   1 
ATOM   2815 C  CB  . SER B 2 116 ? 151.512 137.307 153.183 1.00 10.71  ? 98  SER B CB  1 
ATOM   2816 O  OG  . SER B 2 116 ? 150.394 137.557 152.349 1.00 13.35  ? 98  SER B OG  1 
ATOM   2817 N  N   . TRP B 2 117 ? 150.138 137.574 156.362 1.00 14.30  ? 99  TRP B N   1 
ATOM   2818 C  CA  . TRP B 2 117 ? 148.904 137.311 157.093 1.00 10.07  ? 99  TRP B CA  1 
ATOM   2819 C  C   . TRP B 2 117 ? 148.781 138.378 158.173 1.00 19.19  ? 99  TRP B C   1 
ATOM   2820 O  O   . TRP B 2 117 ? 149.170 138.181 159.320 1.00 16.12  ? 99  TRP B O   1 
ATOM   2821 C  CB  . TRP B 2 117 ? 148.926 135.886 157.663 1.00 12.65  ? 99  TRP B CB  1 
ATOM   2822 C  CG  . TRP B 2 117 ? 149.322 134.888 156.619 1.00 18.65  ? 99  TRP B CG  1 
ATOM   2823 C  CD1 . TRP B 2 117 ? 150.545 134.306 156.457 1.00 14.21  ? 99  TRP B CD1 1 
ATOM   2824 C  CD2 . TRP B 2 117 ? 148.497 134.386 155.568 1.00 8.32   ? 99  TRP B CD2 1 
ATOM   2825 N  NE1 . TRP B 2 117 ? 150.527 133.470 155.371 1.00 6.81   ? 99  TRP B NE1 1 
ATOM   2826 C  CE2 . TRP B 2 117 ? 149.280 133.505 154.809 1.00 8.79   ? 99  TRP B CE2 1 
ATOM   2827 C  CE3 . TRP B 2 117 ? 147.171 134.597 155.198 1.00 4.02   ? 99  TRP B CE3 1 
ATOM   2828 C  CZ2 . TRP B 2 117 ? 148.781 132.843 153.707 1.00 11.46  ? 99  TRP B CZ2 1 
ATOM   2829 C  CZ3 . TRP B 2 117 ? 146.681 133.938 154.109 1.00 8.64   ? 99  TRP B CZ3 1 
ATOM   2830 C  CH2 . TRP B 2 117 ? 147.479 133.070 153.375 1.00 14.00  ? 99  TRP B CH2 1 
ATOM   2831 N  N   . VAL B 2 118 ? 148.231 139.525 157.786 1.00 20.65  ? 100 VAL B N   1 
ATOM   2832 C  CA  . VAL B 2 118 ? 148.105 140.692 158.648 1.00 10.29  ? 100 VAL B CA  1 
ATOM   2833 C  C   . VAL B 2 118 ? 146.627 140.909 158.931 1.00 18.01  ? 100 VAL B C   1 
ATOM   2834 O  O   . VAL B 2 118 ? 145.810 140.952 158.005 1.00 16.31  ? 100 VAL B O   1 
ATOM   2835 C  CB  . VAL B 2 118 ? 148.750 141.936 158.009 1.00 7.07   ? 100 VAL B CB  1 
ATOM   2836 C  CG1 . VAL B 2 118 ? 148.447 141.995 156.534 1.00 13.02  ? 100 VAL B CG1 1 
ATOM   2837 C  CG2 . VAL B 2 118 ? 148.280 143.195 158.689 1.00 13.31  ? 100 VAL B CG2 1 
ATOM   2838 N  N   . MET B 2 119 ? 146.286 141.037 160.211 1.00 15.29  ? 101 MET B N   1 
ATOM   2839 C  CA  . MET B 2 119 ? 144.906 141.100 160.650 1.00 9.45   ? 101 MET B CA  1 
ATOM   2840 C  C   . MET B 2 119 ? 144.500 142.451 161.216 1.00 9.60   ? 101 MET B C   1 
ATOM   2841 O  O   . MET B 2 119 ? 143.314 142.649 161.489 1.00 18.31  ? 101 MET B O   1 
ATOM   2842 C  CB  . MET B 2 119 ? 144.645 140.017 161.706 1.00 14.30  ? 101 MET B CB  1 
ATOM   2843 C  CG  . MET B 2 119 ? 144.503 138.613 161.148 1.00 15.62  ? 101 MET B CG  1 
ATOM   2844 S  SD  . MET B 2 119 ? 144.807 137.353 162.387 1.00 28.07  ? 101 MET B SD  1 
ATOM   2845 C  CE  . MET B 2 119 ? 143.261 136.463 162.350 1.00 22.75  ? 101 MET B CE  1 
ATOM   2846 N  N   . THR B 2 120 ? 145.435 143.379 161.400 1.00 5.04   ? 102 THR B N   1 
ATOM   2847 C  CA  . THR B 2 120 ? 145.109 144.661 162.007 1.00 5.91   ? 102 THR B CA  1 
ATOM   2848 C  C   . THR B 2 120 ? 146.130 145.710 161.597 1.00 15.45  ? 102 THR B C   1 
ATOM   2849 O  O   . THR B 2 120 ? 147.238 145.390 161.161 1.00 21.18  ? 102 THR B O   1 
ATOM   2850 C  CB  . THR B 2 120 ? 145.050 144.558 163.531 1.00 12.22  ? 102 THR B CB  1 
ATOM   2851 O  OG1 . THR B 2 120 ? 144.754 145.844 164.079 1.00 18.34  ? 102 THR B OG1 1 
ATOM   2852 C  CG2 . THR B 2 120 ? 146.368 144.078 164.084 1.00 3.65   ? 102 THR B CG2 1 
ATOM   2853 N  N   . CYS B 2 121 ? 145.733 146.974 161.748 1.00 14.19  ? 103 CYS B N   1 
ATOM   2854 C  CA  . CYS B 2 121 ? 146.604 148.119 161.517 1.00 4.15   ? 103 CYS B CA  1 
ATOM   2855 C  C   . CYS B 2 121 ? 146.105 149.291 162.350 1.00 5.11   ? 103 CYS B C   1 
ATOM   2856 O  O   . CYS B 2 121 ? 144.960 149.313 162.799 1.00 14.74  ? 103 CYS B O   1 
ATOM   2857 C  CB  . CYS B 2 121 ? 146.675 148.497 160.032 1.00 4.79   ? 103 CYS B CB  1 
ATOM   2858 S  SG  . CYS B 2 121 ? 145.161 149.113 159.318 1.00 6.74   ? 103 CYS B SG  1 
ATOM   2859 N  N   . ALA B 2 122 ? 146.984 150.266 162.558 1.00 9.94   ? 104 ALA B N   1 
ATOM   2860 C  CA  . ALA B 2 122 ? 146.655 151.437 163.353 1.00 0.01   ? 104 ALA B CA  1 
ATOM   2861 C  C   . ALA B 2 122 ? 147.461 152.627 162.862 1.00 13.20  ? 104 ALA B C   1 
ATOM   2862 O  O   . ALA B 2 122 ? 148.492 152.478 162.209 1.00 20.38  ? 104 ALA B O   1 
ATOM   2863 C  CB  . ALA B 2 122 ? 146.919 151.208 164.840 1.00 0.00   ? 104 ALA B CB  1 
ATOM   2864 N  N   . TYR B 2 123 ? 146.974 153.815 163.200 1.00 18.51  ? 105 TYR B N   1 
ATOM   2865 C  CA  . TYR B 2 123 ? 147.583 155.086 162.842 1.00 0.94   ? 105 TYR B CA  1 
ATOM   2866 C  C   . TYR B 2 123 ? 147.901 155.839 164.123 1.00 10.04  ? 105 TYR B C   1 
ATOM   2867 O  O   . TYR B 2 123 ? 147.041 155.954 164.999 1.00 20.82  ? 105 TYR B O   1 
ATOM   2868 C  CB  . TYR B 2 123 ? 146.627 155.904 161.976 1.00 4.62   ? 105 TYR B CB  1 
ATOM   2869 C  CG  . TYR B 2 123 ? 147.243 156.619 160.803 1.00 16.36  ? 105 TYR B CG  1 
ATOM   2870 C  CD1 . TYR B 2 123 ? 148.474 157.245 160.907 1.00 18.88  ? 105 TYR B CD1 1 
ATOM   2871 C  CD2 . TYR B 2 123 ? 146.584 156.682 159.593 1.00 16.11  ? 105 TYR B CD2 1 
ATOM   2872 C  CE1 . TYR B 2 123 ? 149.031 157.898 159.835 1.00 15.63  ? 105 TYR B CE1 1 
ATOM   2873 C  CE2 . TYR B 2 123 ? 147.133 157.332 158.520 1.00 17.99  ? 105 TYR B CE2 1 
ATOM   2874 C  CZ  . TYR B 2 123 ? 148.351 157.940 158.645 1.00 19.93  ? 105 TYR B CZ  1 
ATOM   2875 O  OH  . TYR B 2 123 ? 148.895 158.591 157.571 1.00 20.22  ? 105 TYR B OH  1 
ATOM   2876 N  N   . ALA B 2 124 ? 149.120 156.346 164.239 1.00 4.53   ? 106 ALA B N   1 
ATOM   2877 C  CA  . ALA B 2 124 ? 149.472 157.108 165.428 1.00 4.15   ? 106 ALA B CA  1 
ATOM   2878 C  C   . ALA B 2 124 ? 148.665 158.402 165.472 1.00 19.33  ? 106 ALA B C   1 
ATOM   2879 O  O   . ALA B 2 124 ? 148.400 159.005 164.429 1.00 26.72  ? 106 ALA B O   1 
ATOM   2880 C  CB  . ALA B 2 124 ? 150.962 157.418 165.454 1.00 0.00   ? 106 ALA B CB  1 
ATOM   2881 N  N   . PRO B 2 125 ? 148.237 158.845 166.657 1.00 16.52  ? 107 PRO B N   1 
ATOM   2882 C  CA  . PRO B 2 125 ? 147.477 160.103 166.728 1.00 13.09  ? 107 PRO B CA  1 
ATOM   2883 C  C   . PRO B 2 125 ? 148.253 161.310 166.231 1.00 15.55  ? 107 PRO B C   1 
ATOM   2884 O  O   . PRO B 2 125 ? 147.641 162.277 165.764 1.00 19.22  ? 107 PRO B O   1 
ATOM   2885 C  CB  . PRO B 2 125 ? 147.126 160.218 168.218 1.00 14.61  ? 107 PRO B CB  1 
ATOM   2886 C  CG  . PRO B 2 125 ? 148.022 159.270 168.913 1.00 15.04  ? 107 PRO B CG  1 
ATOM   2887 C  CD  . PRO B 2 125 ? 148.325 158.177 167.963 1.00 16.66  ? 107 PRO B CD  1 
ATOM   2888 N  N   . SER B 2 126 ? 149.580 161.289 166.316 1.00 18.16  ? 108 SER B N   1 
ATOM   2889 C  CA  . SER B 2 126 ? 150.399 162.350 165.750 1.00 15.33  ? 108 SER B CA  1 
ATOM   2890 C  C   . SER B 2 126 ? 150.642 162.181 164.258 1.00 14.41  ? 108 SER B C   1 
ATOM   2891 O  O   . SER B 2 126 ? 151.075 163.137 163.607 1.00 21.15  ? 108 SER B O   1 
ATOM   2892 C  CB  . SER B 2 126 ? 151.740 162.421 166.476 1.00 23.34  ? 108 SER B CB  1 
ATOM   2893 O  OG  . SER B 2 126 ? 152.516 161.268 166.213 1.00 23.35  ? 108 SER B OG  1 
ATOM   2894 N  N   . GLY B 2 127 ? 150.372 161.003 163.704 1.00 10.40  ? 109 GLY B N   1 
ATOM   2895 C  CA  . GLY B 2 127 ? 150.550 160.758 162.291 1.00 12.39  ? 109 GLY B CA  1 
ATOM   2896 C  C   . GLY B 2 127 ? 151.955 160.417 161.867 1.00 21.12  ? 109 GLY B C   1 
ATOM   2897 O  O   . GLY B 2 127 ? 152.233 160.410 160.665 1.00 23.82  ? 109 GLY B O   1 
ATOM   2898 N  N   . ASN B 2 128 ? 152.852 160.134 162.809 1.00 23.62  ? 110 ASN B N   1 
ATOM   2899 C  CA  . ASN B 2 128 ? 154.246 159.867 162.488 1.00 13.61  ? 110 ASN B CA  1 
ATOM   2900 C  C   . ASN B 2 128 ? 154.565 158.390 162.350 1.00 15.74  ? 110 ASN B C   1 
ATOM   2901 O  O   . ASN B 2 128 ? 155.555 158.053 161.697 1.00 31.95  ? 110 ASN B O   1 
ATOM   2902 C  CB  . ASN B 2 128 ? 155.163 160.455 163.559 1.00 20.61  ? 110 ASN B CB  1 
ATOM   2903 C  CG  . ASN B 2 128 ? 155.177 161.961 163.556 1.00 23.52  ? 110 ASN B CG  1 
ATOM   2904 O  OD1 . ASN B 2 128 ? 154.858 162.598 162.555 1.00 22.09  ? 110 ASN B OD1 1 
ATOM   2905 N  ND2 . ASN B 2 128 ? 155.550 162.545 164.683 1.00 20.10  ? 110 ASN B ND2 1 
ATOM   2906 N  N   . TYR B 2 129 ? 153.771 157.508 162.950 1.00 18.06  ? 111 TYR B N   1 
ATOM   2907 C  CA  . TYR B 2 129 ? 154.032 156.077 162.953 1.00 6.14   ? 111 TYR B CA  1 
ATOM   2908 C  C   . TYR B 2 129 ? 152.808 155.329 162.457 1.00 7.18   ? 111 TYR B C   1 
ATOM   2909 O  O   . TYR B 2 129 ? 151.712 155.876 162.366 1.00 18.26  ? 111 TYR B O   1 
ATOM   2910 C  CB  . TYR B 2 129 ? 154.407 155.570 164.351 1.00 21.29  ? 111 TYR B CB  1 
ATOM   2911 C  CG  . TYR B 2 129 ? 155.674 156.159 164.903 1.00 18.02  ? 111 TYR B CG  1 
ATOM   2912 C  CD1 . TYR B 2 129 ? 156.908 155.664 164.533 1.00 14.67  ? 111 TYR B CD1 1 
ATOM   2913 C  CD2 . TYR B 2 129 ? 155.635 157.209 165.795 1.00 22.30  ? 111 TYR B CD2 1 
ATOM   2914 C  CE1 . TYR B 2 129 ? 158.066 156.204 165.033 1.00 22.67  ? 111 TYR B CE1 1 
ATOM   2915 C  CE2 . TYR B 2 129 ? 156.787 157.756 166.300 1.00 25.29  ? 111 TYR B CE2 1 
ATOM   2916 C  CZ  . TYR B 2 129 ? 157.999 157.250 165.917 1.00 26.17  ? 111 TYR B CZ  1 
ATOM   2917 O  OH  . TYR B 2 129 ? 159.151 157.795 166.426 1.00 29.53  ? 111 TYR B OH  1 
ATOM   2918 N  N   . VAL B 2 130 ? 153.018 154.057 162.135 1.00 9.88   ? 112 VAL B N   1 
ATOM   2919 C  CA  . VAL B 2 130 ? 151.941 153.139 161.775 1.00 8.69   ? 112 VAL B CA  1 
ATOM   2920 C  C   . VAL B 2 130 ? 152.285 151.770 162.350 1.00 13.67  ? 112 VAL B C   1 
ATOM   2921 O  O   . VAL B 2 130 ? 153.456 151.410 162.462 1.00 22.51  ? 112 VAL B O   1 
ATOM   2922 C  CB  . VAL B 2 130 ? 151.729 153.096 160.239 1.00 4.77   ? 112 VAL B CB  1 
ATOM   2923 C  CG1 . VAL B 2 130 ? 151.061 151.834 159.807 1.00 17.75  ? 112 VAL B CG1 1 
ATOM   2924 C  CG2 . VAL B 2 130 ? 150.879 154.251 159.800 1.00 6.99   ? 112 VAL B CG2 1 
ATOM   2925 N  N   . ALA B 2 131 ? 151.270 151.007 162.750 1.00 8.43   ? 113 ALA B N   1 
ATOM   2926 C  CA  . ALA B 2 131 ? 151.499 149.683 163.314 1.00 4.26   ? 113 ALA B CA  1 
ATOM   2927 C  C   . ALA B 2 131 ? 150.686 148.636 162.575 1.00 11.09  ? 113 ALA B C   1 
ATOM   2928 O  O   . ALA B 2 131 ? 149.666 148.941 161.960 1.00 20.17  ? 113 ALA B O   1 
ATOM   2929 C  CB  . ALA B 2 131 ? 151.155 149.629 164.798 1.00 7.30   ? 113 ALA B CB  1 
ATOM   2930 N  N   . CYS B 2 132 ? 151.162 147.394 162.627 1.00 13.22  ? 114 CYS B N   1 
ATOM   2931 C  CA  . CYS B 2 132 ? 150.411 146.272 162.076 1.00 8.09   ? 114 CYS B CA  1 
ATOM   2932 C  C   . CYS B 2 132 ? 150.814 144.985 162.785 1.00 16.04  ? 114 CYS B C   1 
ATOM   2933 O  O   . CYS B 2 132 ? 151.824 144.926 163.483 1.00 15.44  ? 114 CYS B O   1 
ATOM   2934 C  CB  . CYS B 2 132 ? 150.604 146.150 160.559 1.00 4.58   ? 114 CYS B CB  1 
ATOM   2935 S  SG  . CYS B 2 132 ? 152.204 145.542 160.024 1.00 21.96  ? 114 CYS B SG  1 
ATOM   2936 N  N   . GLY B 2 133 ? 149.998 143.952 162.613 1.00 12.22  ? 115 GLY B N   1 
ATOM   2937 C  CA  . GLY B 2 133 ? 150.290 142.656 163.200 1.00 0.00   ? 115 GLY B CA  1 
ATOM   2938 C  C   . GLY B 2 133 ? 149.387 141.603 162.605 1.00 6.64   ? 115 GLY B C   1 
ATOM   2939 O  O   . GLY B 2 133 ? 148.492 141.901 161.819 1.00 12.43  ? 115 GLY B O   1 
ATOM   2940 N  N   . GLY B 2 134 ? 149.626 140.354 162.993 1.00 5.09   ? 116 GLY B N   1 
ATOM   2941 C  CA  . GLY B 2 134 ? 148.817 139.263 162.479 1.00 3.33   ? 116 GLY B CA  1 
ATOM   2942 C  C   . GLY B 2 134 ? 149.197 137.887 162.979 1.00 8.70   ? 116 GLY B C   1 
ATOM   2943 O  O   . GLY B 2 134 ? 149.590 137.732 164.135 1.00 18.14  ? 116 GLY B O   1 
ATOM   2944 N  N   . LEU B 2 135 ? 149.101 136.877 162.111 1.00 9.50   ? 117 LEU B N   1 
ATOM   2945 C  CA  . LEU B 2 135 ? 149.382 135.487 162.469 1.00 13.63  ? 117 LEU B CA  1 
ATOM   2946 C  C   . LEU B 2 135 ? 150.838 135.224 162.809 1.00 14.39  ? 117 LEU B C   1 
ATOM   2947 O  O   . LEU B 2 135 ? 151.190 134.070 163.051 1.00 21.13  ? 117 LEU B O   1 
ATOM   2948 C  CB  . LEU B 2 135 ? 148.977 134.544 161.340 1.00 8.15   ? 117 LEU B CB  1 
ATOM   2949 C  CG  . LEU B 2 135 ? 147.508 134.195 161.140 1.00 12.42  ? 117 LEU B CG  1 
ATOM   2950 C  CD1 . LEU B 2 135 ? 147.386 133.362 159.898 1.00 11.36  ? 117 LEU B CD1 1 
ATOM   2951 C  CD2 . LEU B 2 135 ? 146.956 133.450 162.325 1.00 17.83  ? 117 LEU B CD2 1 
ATOM   2952 N  N   . ASP B 2 136 ? 151.692 136.234 162.813 1.00 10.15  ? 118 ASP B N   1 
ATOM   2953 C  CA  . ASP B 2 136 ? 153.082 136.082 163.209 1.00 2.07   ? 118 ASP B CA  1 
ATOM   2954 C  C   . ASP B 2 136 ? 153.323 136.397 164.678 1.00 12.91  ? 118 ASP B C   1 
ATOM   2955 O  O   . ASP B 2 136 ? 154.459 136.260 165.141 1.00 19.37  ? 118 ASP B O   1 
ATOM   2956 C  CB  . ASP B 2 136 ? 153.964 136.962 162.323 1.00 11.14  ? 118 ASP B CB  1 
ATOM   2957 C  CG  . ASP B 2 136 ? 153.460 138.388 162.226 1.00 22.21  ? 118 ASP B CG  1 
ATOM   2958 O  OD1 . ASP B 2 136 ? 153.810 139.221 163.081 1.00 21.66  ? 118 ASP B OD1 1 
ATOM   2959 O  OD2 . ASP B 2 136 ? 152.721 138.680 161.267 1.00 26.17  ? 118 ASP B OD2 1 
ATOM   2960 N  N   . ASN B 2 137 ? 152.282 136.799 165.414 1.00 5.09   ? 119 ASN B N   1 
ATOM   2961 C  CA  . ASN B 2 137 ? 152.315 137.073 166.849 1.00 6.27   ? 119 ASN B CA  1 
ATOM   2962 C  C   . ASN B 2 137 ? 153.161 138.286 167.214 1.00 18.87  ? 119 ASN B C   1 
ATOM   2963 O  O   . ASN B 2 137 ? 153.581 138.413 168.364 1.00 24.34  ? 119 ASN B O   1 
ATOM   2964 C  CB  . ASN B 2 137 ? 152.807 135.859 167.648 1.00 4.33   ? 119 ASN B CB  1 
ATOM   2965 C  CG  . ASN B 2 137 ? 152.027 134.595 167.346 1.00 16.03  ? 119 ASN B CG  1 
ATOM   2966 O  OD1 . ASN B 2 137 ? 150.973 134.636 166.727 1.00 25.54  ? 119 ASN B OD1 1 
ATOM   2967 N  ND2 . ASN B 2 137 ? 152.551 133.461 167.785 1.00 16.99  ? 119 ASN B ND2 1 
ATOM   2968 N  N   . ILE B 2 138 ? 153.410 139.199 166.275 1.00 12.70  ? 120 ILE B N   1 
ATOM   2969 C  CA  . ILE B 2 138 ? 154.344 140.306 166.466 1.00 12.73  ? 120 ILE B CA  1 
ATOM   2970 C  C   . ILE B 2 138 ? 153.685 141.598 166.006 1.00 12.17  ? 120 ILE B C   1 
ATOM   2971 O  O   . ILE B 2 138 ? 152.939 141.602 165.023 1.00 17.32  ? 120 ILE B O   1 
ATOM   2972 C  CB  . ILE B 2 138 ? 155.664 140.063 165.698 1.00 16.68  ? 120 ILE B CB  1 
ATOM   2973 C  CG1 . ILE B 2 138 ? 156.459 138.934 166.339 1.00 13.87  ? 120 ILE B CG1 1 
ATOM   2974 C  CG2 . ILE B 2 138 ? 156.519 141.302 165.658 1.00 14.99  ? 120 ILE B CG2 1 
ATOM   2975 C  CD1 . ILE B 2 138 ? 157.814 138.760 165.750 1.00 17.53  ? 120 ILE B CD1 1 
ATOM   2976 N  N   . CYS B 2 139 ? 153.953 142.694 166.721 1.00 17.79  ? 121 CYS B N   1 
ATOM   2977 C  CA  . CYS B 2 139 ? 153.488 144.024 166.333 1.00 14.74  ? 121 CYS B CA  1 
ATOM   2978 C  C   . CYS B 2 139 ? 154.647 144.816 165.739 1.00 17.95  ? 121 CYS B C   1 
ATOM   2979 O  O   . CYS B 2 139 ? 155.660 145.029 166.405 1.00 16.93  ? 121 CYS B O   1 
ATOM   2980 C  CB  . CYS B 2 139 ? 152.899 144.772 167.526 1.00 9.59   ? 121 CYS B CB  1 
ATOM   2981 S  SG  . CYS B 2 139 ? 151.706 146.043 167.085 1.00 22.08  ? 121 CYS B SG  1 
ATOM   2982 N  N   . SER B 2 140 ? 154.492 145.266 164.499 1.00 16.24  ? 122 SER B N   1 
ATOM   2983 C  CA  . SER B 2 140 ? 155.531 145.998 163.791 1.00 11.47  ? 122 SER B CA  1 
ATOM   2984 C  C   . SER B 2 140 ? 155.151 147.467 163.706 1.00 15.66  ? 122 SER B C   1 
ATOM   2985 O  O   . SER B 2 140 ? 154.035 147.798 163.292 1.00 27.54  ? 122 SER B O   1 
ATOM   2986 C  CB  . SER B 2 140 ? 155.743 145.427 162.390 1.00 18.61  ? 122 SER B CB  1 
ATOM   2987 O  OG  . SER B 2 140 ? 156.212 144.095 162.441 1.00 20.01  ? 122 SER B OG  1 
ATOM   2988 N  N   . ILE B 2 141 ? 156.086 148.333 164.096 1.00 17.34  ? 123 ILE B N   1 
ATOM   2989 C  CA  . ILE B 2 141 ? 155.913 149.781 164.119 1.00 15.40  ? 123 ILE B CA  1 
ATOM   2990 C  C   . ILE B 2 141 ? 156.839 150.376 163.070 1.00 17.82  ? 123 ILE B C   1 
ATOM   2991 O  O   . ILE B 2 141 ? 158.061 150.183 163.136 1.00 28.70  ? 123 ILE B O   1 
ATOM   2992 C  CB  . ILE B 2 141 ? 156.225 150.368 165.504 1.00 17.19  ? 123 ILE B CB  1 
ATOM   2993 C  CG1 . ILE B 2 141 ? 155.641 149.495 166.620 1.00 16.95  ? 123 ILE B CG1 1 
ATOM   2994 C  CG2 . ILE B 2 141 ? 155.748 151.797 165.603 1.00 15.56  ? 123 ILE B CG2 1 
ATOM   2995 C  CD1 . ILE B 2 141 ? 154.205 149.757 166.934 1.00 14.17  ? 123 ILE B CD1 1 
ATOM   2996 N  N   . TYR B 2 142 ? 156.255 151.114 162.125 1.00 14.63  ? 124 TYR B N   1 
ATOM   2997 C  CA  . TYR B 2 142 ? 156.942 151.731 161.000 1.00 15.02  ? 124 TYR B CA  1 
ATOM   2998 C  C   . TYR B 2 142 ? 156.959 153.242 161.156 1.00 22.27  ? 124 TYR B C   1 
ATOM   2999 O  O   . TYR B 2 142 ? 155.950 153.850 161.527 1.00 27.10  ? 124 TYR B O   1 
ATOM   3000 C  CB  . TYR B 2 142 ? 156.259 151.390 159.676 1.00 12.19  ? 124 TYR B CB  1 
ATOM   3001 C  CG  . TYR B 2 142 ? 156.070 149.923 159.427 1.00 17.70  ? 124 TYR B CG  1 
ATOM   3002 C  CD1 . TYR B 2 142 ? 157.057 149.175 158.817 1.00 16.61  ? 124 TYR B CD1 1 
ATOM   3003 C  CD2 . TYR B 2 142 ? 154.905 149.283 159.805 1.00 19.99  ? 124 TYR B CD2 1 
ATOM   3004 C  CE1 . TYR B 2 142 ? 156.888 147.839 158.590 1.00 18.82  ? 124 TYR B CE1 1 
ATOM   3005 C  CE2 . TYR B 2 142 ? 154.731 147.946 159.585 1.00 14.31  ? 124 TYR B CE2 1 
ATOM   3006 C  CZ  . TYR B 2 142 ? 155.727 147.229 158.975 1.00 20.62  ? 124 TYR B CZ  1 
ATOM   3007 O  OH  . TYR B 2 142 ? 155.561 145.888 158.750 1.00 25.16  ? 124 TYR B OH  1 
ATOM   3008 N  N   . ASN B 2 143 ? 158.103 153.834 160.831 1.00 23.34  ? 125 ASN B N   1 
ATOM   3009 C  CA  . ASN B 2 143 ? 158.335 155.269 160.934 1.00 21.30  ? 125 ASN B CA  1 
ATOM   3010 C  C   . ASN B 2 143 ? 158.000 155.916 159.597 1.00 28.15  ? 125 ASN B C   1 
ATOM   3011 O  O   . ASN B 2 143 ? 158.650 155.637 158.588 1.00 41.09  ? 125 ASN B O   1 
ATOM   3012 C  CB  . ASN B 2 143 ? 159.787 155.531 161.316 1.00 27.70  ? 125 ASN B CB  1 
ATOM   3013 C  CG  . ASN B 2 143 ? 160.004 156.911 161.866 1.00 35.11  ? 125 ASN B CG  1 
ATOM   3014 O  OD1 . ASN B 2 143 ? 159.103 157.743 161.858 1.00 36.69  ? 125 ASN B OD1 1 
ATOM   3015 N  ND2 . ASN B 2 143 ? 161.209 157.169 162.350 1.00 33.16  ? 125 ASN B ND2 1 
ATOM   3016 N  N   . LEU B 2 144 ? 156.988 156.781 159.584 1.00 26.26  ? 126 LEU B N   1 
ATOM   3017 C  CA  . LEU B 2 144 ? 156.601 157.442 158.344 1.00 21.85  ? 126 LEU B CA  1 
ATOM   3018 C  C   . LEU B 2 144 ? 157.459 158.670 158.068 1.00 30.46  ? 126 LEU B C   1 
ATOM   3019 O  O   . LEU B 2 144 ? 157.784 158.955 156.912 1.00 32.32  ? 126 LEU B O   1 
ATOM   3020 C  CB  . LEU B 2 144 ? 155.125 157.830 158.395 1.00 16.73  ? 126 LEU B CB  1 
ATOM   3021 C  CG  . LEU B 2 144 ? 154.078 156.727 158.483 1.00 12.84  ? 126 LEU B CG  1 
ATOM   3022 C  CD1 . LEU B 2 144 ? 152.734 157.294 158.178 1.00 16.69  ? 126 LEU B CD1 1 
ATOM   3023 C  CD2 . LEU B 2 144 ? 154.383 155.618 157.530 1.00 21.92  ? 126 LEU B CD2 1 
ATOM   3024 N  N   . LYS B 2 145 ? 157.833 159.406 159.112 1.00 35.43  ? 127 LYS B N   1 
ATOM   3025 C  CA  . LYS B 2 145 ? 158.592 160.650 158.967 1.00 38.37  ? 127 LYS B CA  1 
ATOM   3026 C  C   . LYS B 2 145 ? 160.094 160.390 159.073 1.00 42.47  ? 127 LYS B C   1 
ATOM   3027 O  O   . LYS B 2 145 ? 160.803 160.985 159.880 1.00 43.46  ? 127 LYS B O   1 
ATOM   3028 C  CB  . LYS B 2 145 ? 158.147 161.669 160.010 1.00 38.13  ? 127 LYS B CB  1 
ATOM   3029 C  CG  . LYS B 2 145 ? 156.684 162.101 159.953 1.00 39.89  ? 127 LYS B CG  1 
ATOM   3030 C  CD  . LYS B 2 145 ? 156.318 162.829 158.684 1.00 37.98  ? 127 LYS B CD  1 
ATOM   3031 C  CE  . LYS B 2 145 ? 154.887 163.281 158.740 1.00 37.43  ? 127 LYS B CE  1 
ATOM   3032 N  NZ  . LYS B 2 145 ? 154.517 163.977 157.483 1.00 38.13  ? 127 LYS B NZ  1 
ATOM   3033 N  N   . THR B 2 146 ? 160.578 159.482 158.233 1.00 63.80  ? 128 THR B N   1 
ATOM   3034 C  CA  . THR B 2 146 ? 161.982 159.102 158.289 1.00 66.66  ? 128 THR B CA  1 
ATOM   3035 C  C   . THR B 2 146 ? 162.866 160.252 157.823 1.00 70.17  ? 128 THR B C   1 
ATOM   3036 O  O   . THR B 2 146 ? 162.512 160.998 156.905 1.00 69.76  ? 128 THR B O   1 
ATOM   3037 C  CB  . THR B 2 146 ? 162.231 157.864 157.431 1.00 68.04  ? 128 THR B CB  1 
ATOM   3038 O  OG1 . THR B 2 146 ? 161.465 156.768 157.939 1.00 64.62  ? 128 THR B OG1 1 
ATOM   3039 C  CG2 . THR B 2 146 ? 163.691 157.471 157.459 1.00 68.54  ? 128 THR B CG2 1 
ATOM   3040 N  N   . ARG B 2 147 ? 164.023 160.399 158.475 1.00 94.49  ? 129 ARG B N   1 
ATOM   3041 C  CA  . ARG B 2 147 ? 164.997 161.406 158.065 1.00 96.58  ? 129 ARG B CA  1 
ATOM   3042 C  C   . ARG B 2 147 ? 165.414 161.221 156.611 1.00 96.07  ? 129 ARG B C   1 
ATOM   3043 O  O   . ARG B 2 147 ? 165.702 162.196 155.908 1.00 95.77  ? 129 ARG B O   1 
ATOM   3044 C  CB  . ARG B 2 147 ? 166.218 161.343 158.982 1.00 96.67  ? 129 ARG B CB  1 
ATOM   3045 C  CG  . ARG B 2 147 ? 167.262 162.413 158.723 1.00 96.57  ? 129 ARG B CG  1 
ATOM   3046 C  CD  . ARG B 2 147 ? 168.454 162.232 159.647 1.00 95.51  ? 129 ARG B CD  1 
ATOM   3047 N  NE  . ARG B 2 147 ? 169.499 163.215 159.389 1.00 97.66  ? 129 ARG B NE  1 
ATOM   3048 C  CZ  . ARG B 2 147 ? 169.822 164.198 160.218 1.00 97.57  ? 129 ARG B CZ  1 
ATOM   3049 N  NH1 . ARG B 2 147 ? 169.197 164.362 161.373 1.00 96.10  ? 129 ARG B NH1 1 
ATOM   3050 N  NH2 . ARG B 2 147 ? 170.797 165.036 159.880 1.00 96.76  ? 129 ARG B NH2 1 
ATOM   3051 N  N   . GLU B 2 148 ? 165.457 159.976 156.145 1.00 99.20  ? 130 GLU B N   1 
ATOM   3052 C  CA  . GLU B 2 148 ? 165.823 159.669 154.770 1.00 99.81  ? 130 GLU B CA  1 
ATOM   3053 C  C   . GLU B 2 148 ? 164.624 159.624 153.833 1.00 99.34  ? 130 GLU B C   1 
ATOM   3054 O  O   . GLU B 2 148 ? 164.807 159.438 152.626 1.00 99.93  ? 130 GLU B O   1 
ATOM   3055 C  CB  . GLU B 2 148 ? 166.568 158.331 154.713 1.00 100.54 ? 130 GLU B CB  1 
ATOM   3056 C  CG  . GLU B 2 148 ? 167.786 158.262 155.617 1.00 99.74  ? 130 GLU B CG  1 
ATOM   3057 C  CD  . GLU B 2 148 ? 169.008 158.909 154.999 1.00 101.36 ? 130 GLU B CD  1 
ATOM   3058 O  OE1 . GLU B 2 148 ? 168.982 159.188 153.782 1.00 100.35 ? 130 GLU B OE1 1 
ATOM   3059 O  OE2 . GLU B 2 148 ? 169.994 159.141 155.730 1.00 102.12 ? 130 GLU B OE2 1 
ATOM   3060 N  N   . GLY B 2 149 ? 163.409 159.787 154.353 1.00 94.67  ? 131 GLY B N   1 
ATOM   3061 C  CA  . GLY B 2 149 ? 162.226 159.758 153.518 1.00 95.31  ? 131 GLY B CA  1 
ATOM   3062 C  C   . GLY B 2 149 ? 161.754 158.382 153.117 1.00 96.18  ? 131 GLY B C   1 
ATOM   3063 O  O   . GLY B 2 149 ? 160.948 158.265 152.189 1.00 94.10  ? 131 GLY B O   1 
ATOM   3064 N  N   . ASN B 2 150 ? 162.230 157.332 153.783 1.00 76.08  ? 132 ASN B N   1 
ATOM   3065 C  CA  . ASN B 2 150 ? 161.887 155.953 153.451 1.00 74.17  ? 132 ASN B CA  1 
ATOM   3066 C  C   . ASN B 2 150 ? 161.253 155.289 154.665 1.00 69.69  ? 132 ASN B C   1 
ATOM   3067 O  O   . ASN B 2 150 ? 161.828 155.305 155.757 1.00 68.86  ? 132 ASN B O   1 
ATOM   3068 C  CB  . ASN B 2 150 ? 163.126 155.177 153.000 1.00 73.20  ? 132 ASN B CB  1 
ATOM   3069 C  CG  . ASN B 2 150 ? 162.809 154.134 151.949 1.00 72.02  ? 132 ASN B CG  1 
ATOM   3070 O  OD1 . ASN B 2 150 ? 161.815 154.243 151.232 1.00 73.01  ? 132 ASN B OD1 1 
ATOM   3071 N  ND2 . ASN B 2 150 ? 163.651 153.114 151.856 1.00 70.08  ? 132 ASN B ND2 1 
ATOM   3072 N  N   . VAL B 2 151 ? 160.081 154.691 154.470 1.00 50.73  ? 133 VAL B N   1 
ATOM   3073 C  CA  . VAL B 2 151 ? 159.369 154.027 155.557 1.00 43.85  ? 133 VAL B CA  1 
ATOM   3074 C  C   . VAL B 2 151 ? 160.146 152.773 155.943 1.00 44.98  ? 133 VAL B C   1 
ATOM   3075 O  O   . VAL B 2 151 ? 160.301 151.856 155.133 1.00 47.83  ? 133 VAL B O   1 
ATOM   3076 C  CB  . VAL B 2 151 ? 157.932 153.689 155.159 1.00 40.14  ? 133 VAL B CB  1 
ATOM   3077 C  CG1 . VAL B 2 151 ? 157.067 153.580 156.382 1.00 41.13  ? 133 VAL B CG1 1 
ATOM   3078 C  CG2 . VAL B 2 151 ? 157.393 154.748 154.234 1.00 42.11  ? 133 VAL B CG2 1 
ATOM   3079 N  N   . ARG B 2 152 ? 160.627 152.726 157.183 1.00 41.90  ? 134 ARG B N   1 
ATOM   3080 C  CA  . ARG B 2 152 ? 161.431 151.620 157.677 1.00 42.56  ? 134 ARG B CA  1 
ATOM   3081 C  C   . ARG B 2 152 ? 160.865 151.118 158.995 1.00 39.44  ? 134 ARG B C   1 
ATOM   3082 O  O   . ARG B 2 152 ? 160.294 151.886 159.771 1.00 38.57  ? 134 ARG B O   1 
ATOM   3083 C  CB  . ARG B 2 152 ? 162.892 152.033 157.868 1.00 43.41  ? 134 ARG B CB  1 
ATOM   3084 C  CG  . ARG B 2 152 ? 163.122 153.000 159.016 1.00 43.49  ? 134 ARG B CG  1 
ATOM   3085 C  CD  . ARG B 2 152 ? 164.596 153.089 159.361 1.00 44.14  ? 134 ARG B CD  1 
ATOM   3086 N  NE  . ARG B 2 152 ? 165.386 153.543 158.224 1.00 49.82  ? 134 ARG B NE  1 
ATOM   3087 C  CZ  . ARG B 2 152 ? 165.976 154.728 158.146 1.00 51.56  ? 134 ARG B CZ  1 
ATOM   3088 N  NH1 . ARG B 2 152 ? 165.907 155.601 159.137 1.00 48.59  ? 134 ARG B NH1 1 
ATOM   3089 N  NH2 . ARG B 2 152 ? 166.654 155.044 157.047 1.00 48.69  ? 134 ARG B NH2 1 
ATOM   3090 N  N   . VAL B 2 153 ? 161.043 149.823 159.247 1.00 33.78  ? 135 VAL B N   1 
ATOM   3091 C  CA  . VAL B 2 153 ? 160.518 149.199 160.459 1.00 30.37  ? 135 VAL B CA  1 
ATOM   3092 C  C   . VAL B 2 153 ? 161.266 149.775 161.654 1.00 28.13  ? 135 VAL B C   1 
ATOM   3093 O  O   . VAL B 2 153 ? 162.451 149.498 161.853 1.00 34.27  ? 135 VAL B O   1 
ATOM   3094 C  CB  . VAL B 2 153 ? 160.642 147.674 160.414 1.00 23.97  ? 135 VAL B CB  1 
ATOM   3095 C  CG1 . VAL B 2 153 ? 159.798 147.050 161.500 1.00 22.94  ? 135 VAL B CG1 1 
ATOM   3096 C  CG2 . VAL B 2 153 ? 160.225 147.156 159.065 1.00 27.24  ? 135 VAL B CG2 1 
ATOM   3097 N  N   . SER B 2 154 ? 160.574 150.587 162.448 1.00 20.60  ? 136 SER B N   1 
ATOM   3098 C  CA  . SER B 2 154 ? 161.193 151.162 163.631 1.00 22.09  ? 136 SER B CA  1 
ATOM   3099 C  C   . SER B 2 154 ? 161.325 150.132 164.743 1.00 30.93  ? 136 SER B C   1 
ATOM   3100 O  O   . SER B 2 154 ? 162.342 150.098 165.444 1.00 37.20  ? 136 SER B O   1 
ATOM   3101 C  CB  . SER B 2 154 ? 160.385 152.367 164.103 1.00 29.35  ? 136 SER B CB  1 
ATOM   3102 O  OG  . SER B 2 154 ? 160.730 152.734 165.425 1.00 32.91  ? 136 SER B OG  1 
ATOM   3103 N  N   . ARG B 2 155 ? 160.317 149.277 164.919 1.00 28.03  ? 137 ARG B N   1 
ATOM   3104 C  CA  . ARG B 2 155 ? 160.313 148.393 166.079 1.00 22.00  ? 137 ARG B CA  1 
ATOM   3105 C  C   . ARG B 2 155 ? 159.505 147.136 165.796 1.00 23.27  ? 137 ARG B C   1 
ATOM   3106 O  O   . ARG B 2 155 ? 158.560 147.156 165.008 1.00 31.21  ? 137 ARG B O   1 
ATOM   3107 C  CB  . ARG B 2 155 ? 159.753 149.120 167.306 1.00 24.54  ? 137 ARG B CB  1 
ATOM   3108 C  CG  . ARG B 2 155 ? 159.800 148.336 168.596 1.00 27.75  ? 137 ARG B CG  1 
ATOM   3109 C  CD  . ARG B 2 155 ? 161.168 148.390 169.226 1.00 28.85  ? 137 ARG B CD  1 
ATOM   3110 N  NE  . ARG B 2 155 ? 161.652 149.757 169.349 1.00 33.07  ? 137 ARG B NE  1 
ATOM   3111 C  CZ  . ARG B 2 155 ? 162.877 150.081 169.734 1.00 35.60  ? 137 ARG B CZ  1 
ATOM   3112 N  NH1 . ARG B 2 155 ? 163.768 149.157 170.051 1.00 36.32  ? 137 ARG B NH1 1 
ATOM   3113 N  NH2 . ARG B 2 155 ? 163.219 151.364 169.799 1.00 30.76  ? 137 ARG B NH2 1 
ATOM   3114 N  N   . GLU B 2 156 ? 159.887 146.041 166.454 1.00 26.64  ? 138 GLU B N   1 
ATOM   3115 C  CA  . GLU B 2 156 ? 159.135 144.790 166.432 1.00 24.88  ? 138 GLU B CA  1 
ATOM   3116 C  C   . GLU B 2 156 ? 158.920 144.323 167.863 1.00 26.98  ? 138 GLU B C   1 
ATOM   3117 O  O   . GLU B 2 156 ? 159.888 144.048 168.579 1.00 25.11  ? 138 GLU B O   1 
ATOM   3118 C  CB  . GLU B 2 156 ? 159.863 143.715 165.626 1.00 16.49  ? 138 GLU B CB  1 
ATOM   3119 C  CG  . GLU B 2 156 ? 159.773 143.906 164.134 1.00 27.99  ? 138 GLU B CG  1 
ATOM   3120 C  CD  . GLU B 2 156 ? 159.800 142.599 163.381 1.00 34.74  ? 138 GLU B CD  1 
ATOM   3121 O  OE1 . GLU B 2 156 ? 160.675 141.762 163.679 1.00 36.74  ? 138 GLU B OE1 1 
ATOM   3122 O  OE2 . GLU B 2 156 ? 158.950 142.408 162.486 1.00 32.41  ? 138 GLU B OE2 1 
ATOM   3123 N  N   . LEU B 2 157 ? 157.660 144.223 168.271 1.00 24.49  ? 139 LEU B N   1 
ATOM   3124 C  CA  . LEU B 2 157 ? 157.287 143.847 169.626 1.00 19.55  ? 139 LEU B CA  1 
ATOM   3125 C  C   . LEU B 2 157 ? 156.798 142.405 169.619 1.00 23.48  ? 139 LEU B C   1 
ATOM   3126 O  O   . LEU B 2 157 ? 155.808 142.085 168.950 1.00 31.02  ? 139 LEU B O   1 
ATOM   3127 C  CB  . LEU B 2 157 ? 156.204 144.778 170.167 1.00 18.56  ? 139 LEU B CB  1 
ATOM   3128 C  CG  . LEU B 2 157 ? 156.353 146.283 169.944 1.00 20.18  ? 139 LEU B CG  1 
ATOM   3129 C  CD1 . LEU B 2 157 ? 155.001 146.952 170.000 1.00 19.48  ? 139 LEU B CD1 1 
ATOM   3130 C  CD2 . LEU B 2 157 ? 157.278 146.893 170.965 1.00 22.54  ? 139 LEU B CD2 1 
ATOM   3131 N  N   . ALA B 2 158 ? 157.481 141.546 170.374 1.00 17.68  ? 140 ALA B N   1 
ATOM   3132 C  CA  . ALA B 2 158 ? 157.250 140.104 170.351 1.00 22.78  ? 140 ALA B CA  1 
ATOM   3133 C  C   . ALA B 2 158 ? 157.164 139.576 171.779 1.00 27.07  ? 140 ALA B C   1 
ATOM   3134 O  O   . ALA B 2 158 ? 158.191 139.314 172.407 1.00 27.61  ? 140 ALA B O   1 
ATOM   3135 C  CB  . ALA B 2 158 ? 158.356 139.400 169.577 1.00 20.14  ? 140 ALA B CB  1 
ATOM   3136 N  N   . GLY B 2 159 ? 155.948 139.452 172.304 1.00 30.30  ? 141 GLY B N   1 
ATOM   3137 C  CA  . GLY B 2 159 ? 155.738 138.799 173.582 1.00 25.77  ? 141 GLY B CA  1 
ATOM   3138 C  C   . GLY B 2 159 ? 154.417 138.067 173.715 1.00 28.06  ? 141 GLY B C   1 
ATOM   3139 O  O   . GLY B 2 159 ? 154.091 137.561 174.790 1.00 28.75  ? 141 GLY B O   1 
ATOM   3140 N  N   . HIS B 2 160 ? 153.648 138.002 172.637 1.00 25.38  ? 142 HIS B N   1 
ATOM   3141 C  CA  . HIS B 2 160 ? 152.357 137.335 172.634 1.00 18.86  ? 142 HIS B CA  1 
ATOM   3142 C  C   . HIS B 2 160 ? 152.531 135.908 172.133 1.00 16.70  ? 142 HIS B C   1 
ATOM   3143 O  O   . HIS B 2 160 ? 153.441 135.615 171.357 1.00 28.78  ? 142 HIS B O   1 
ATOM   3144 C  CB  . HIS B 2 160 ? 151.354 138.081 171.749 1.00 21.05  ? 142 HIS B CB  1 
ATOM   3145 C  CG  . HIS B 2 160 ? 150.644 139.213 172.434 1.00 30.74  ? 142 HIS B CG  1 
ATOM   3146 N  ND1 . HIS B 2 160 ? 149.968 139.062 173.624 1.00 22.74  ? 142 HIS B ND1 1 
ATOM   3147 C  CD2 . HIS B 2 160 ? 150.482 140.508 172.076 1.00 26.13  ? 142 HIS B CD2 1 
ATOM   3148 C  CE1 . HIS B 2 160 ? 149.432 140.217 173.975 1.00 11.78  ? 142 HIS B CE1 1 
ATOM   3149 N  NE2 . HIS B 2 160 ? 149.729 141.110 173.053 1.00 16.06  ? 142 HIS B NE2 1 
ATOM   3150 N  N   . THR B 2 161 ? 151.656 135.015 172.593 1.00 12.22  ? 143 THR B N   1 
ATOM   3151 C  CA  . THR B 2 161 ? 151.685 133.617 172.181 1.00 11.04  ? 143 THR B CA  1 
ATOM   3152 C  C   . THR B 2 161 ? 150.549 133.276 171.224 1.00 17.83  ? 143 THR B C   1 
ATOM   3153 O  O   . THR B 2 161 ? 150.239 132.100 171.028 1.00 28.73  ? 143 THR B O   1 
ATOM   3154 C  CB  . THR B 2 161 ? 151.649 132.698 173.401 1.00 12.34  ? 143 THR B CB  1 
ATOM   3155 O  OG1 . THR B 2 161 ? 150.717 133.206 174.357 1.00 20.20  ? 143 THR B OG1 1 
ATOM   3156 C  CG2 . THR B 2 161 ? 153.014 132.622 174.045 1.00 17.00  ? 143 THR B CG2 1 
ATOM   3157 N  N   . GLY B 2 162 ? 149.927 134.283 170.625 1.00 18.11  ? 144 GLY B N   1 
ATOM   3158 C  CA  . GLY B 2 162 ? 148.878 134.063 169.651 1.00 0.00   ? 144 GLY B CA  1 
ATOM   3159 C  C   . GLY B 2 162 ? 148.719 135.288 168.786 1.00 6.70   ? 144 GLY B C   1 
ATOM   3160 O  O   . GLY B 2 162 ? 149.146 136.386 169.149 1.00 17.45  ? 144 GLY B O   1 
ATOM   3161 N  N   . TYR B 2 163 ? 148.074 135.087 167.638 1.00 6.02   ? 145 TYR B N   1 
ATOM   3162 C  CA  . TYR B 2 163 ? 147.938 136.133 166.634 1.00 7.35   ? 145 TYR B CA  1 
ATOM   3163 C  C   . TYR B 2 163 ? 147.353 137.401 167.241 1.00 16.83  ? 145 TYR B C   1 
ATOM   3164 O  O   . TYR B 2 163 ? 146.538 137.351 168.163 1.00 25.77  ? 145 TYR B O   1 
ATOM   3165 C  CB  . TYR B 2 163 ? 147.052 135.643 165.487 1.00 0.00   ? 145 TYR B CB  1 
ATOM   3166 C  CG  . TYR B 2 163 ? 145.624 135.368 165.882 1.00 9.93   ? 145 TYR B CG  1 
ATOM   3167 C  CD1 . TYR B 2 163 ? 145.246 134.133 166.377 1.00 13.86  ? 145 TYR B CD1 1 
ATOM   3168 C  CD2 . TYR B 2 163 ? 144.652 136.337 165.752 1.00 11.59  ? 145 TYR B CD2 1 
ATOM   3169 C  CE1 . TYR B 2 163 ? 143.950 133.879 166.735 1.00 11.25  ? 145 TYR B CE1 1 
ATOM   3170 C  CE2 . TYR B 2 163 ? 143.352 136.092 166.112 1.00 9.40   ? 145 TYR B CE2 1 
ATOM   3171 C  CZ  . TYR B 2 163 ? 143.007 134.862 166.601 1.00 17.53  ? 145 TYR B CZ  1 
ATOM   3172 O  OH  . TYR B 2 163 ? 141.707 134.620 166.960 1.00 20.79  ? 145 TYR B OH  1 
ATOM   3173 N  N   . LEU B 2 164 ? 147.782 138.548 166.722 1.00 6.73   ? 146 LEU B N   1 
ATOM   3174 C  CA  . LEU B 2 164 ? 147.248 139.827 167.166 1.00 9.00   ? 146 LEU B CA  1 
ATOM   3175 C  C   . LEU B 2 164 ? 145.950 140.163 166.451 1.00 7.08   ? 146 LEU B C   1 
ATOM   3176 O  O   . LEU B 2 164 ? 145.867 140.087 165.224 1.00 9.92   ? 146 LEU B O   1 
ATOM   3177 C  CB  . LEU B 2 164 ? 148.259 140.943 166.938 1.00 13.40  ? 146 LEU B CB  1 
ATOM   3178 C  CG  . LEU B 2 164 ? 149.305 141.142 168.018 1.00 16.23  ? 146 LEU B CG  1 
ATOM   3179 C  CD1 . LEU B 2 164 ? 150.577 140.471 167.629 1.00 21.34  ? 146 LEU B CD1 1 
ATOM   3180 C  CD2 . LEU B 2 164 ? 149.513 142.617 168.205 1.00 12.23  ? 146 LEU B CD2 1 
ATOM   3181 N  N   . SER B 2 165 ? 144.945 140.562 167.226 1.00 3.35   ? 147 SER B N   1 
ATOM   3182 C  CA  . SER B 2 165 ? 143.648 140.939 166.689 1.00 4.15   ? 147 SER B CA  1 
ATOM   3183 C  C   . SER B 2 165 ? 143.458 142.441 166.571 1.00 15.80  ? 147 SER B C   1 
ATOM   3184 O  O   . SER B 2 165 ? 142.732 142.889 165.679 1.00 17.53  ? 147 SER B O   1 
ATOM   3185 C  CB  . SER B 2 165 ? 142.528 140.377 167.564 1.00 7.97   ? 147 SER B CB  1 
ATOM   3186 O  OG  . SER B 2 165 ? 142.509 138.968 167.540 1.00 15.81  ? 147 SER B OG  1 
ATOM   3187 N  N   . CYS B 2 166 ? 144.074 143.228 167.450 1.00 15.51  ? 148 CYS B N   1 
ATOM   3188 C  CA  . CYS B 2 166 ? 143.884 144.669 167.445 1.00 10.02  ? 148 CYS B CA  1 
ATOM   3189 C  C   . CYS B 2 166 ? 145.099 145.333 168.065 1.00 8.87   ? 148 CYS B C   1 
ATOM   3190 O  O   . CYS B 2 166 ? 145.862 144.708 168.800 1.00 8.18   ? 148 CYS B O   1 
ATOM   3191 C  CB  . CYS B 2 166 ? 142.612 145.070 168.195 1.00 13.45  ? 148 CYS B CB  1 
ATOM   3192 S  SG  . CYS B 2 166 ? 141.804 146.560 167.576 1.00 28.07  ? 148 CYS B SG  1 
ATOM   3193 N  N   . CYS B 2 167 ? 145.274 146.611 167.736 1.00 15.95  ? 149 CYS B N   1 
ATOM   3194 C  CA  . CYS B 2 167 ? 146.304 147.456 168.320 1.00 11.96  ? 149 CYS B CA  1 
ATOM   3195 C  C   . CYS B 2 167 ? 145.836 148.896 168.224 1.00 11.93  ? 149 CYS B C   1 
ATOM   3196 O  O   . CYS B 2 167 ? 145.159 149.273 167.267 1.00 23.00  ? 149 CYS B O   1 
ATOM   3197 C  CB  . CYS B 2 167 ? 147.665 147.284 167.630 1.00 15.09  ? 149 CYS B CB  1 
ATOM   3198 S  SG  . CYS B 2 167 ? 147.643 147.232 165.830 1.00 21.12  ? 149 CYS B SG  1 
ATOM   3199 N  N   . ARG B 2 168 ? 146.188 149.698 169.225 1.00 11.96  ? 150 ARG B N   1 
ATOM   3200 C  CA  . ARG B 2 168 ? 145.730 151.081 169.290 1.00 8.80   ? 150 ARG B CA  1 
ATOM   3201 C  C   . ARG B 2 168 ? 146.790 151.915 169.986 1.00 11.05  ? 150 ARG B C   1 
ATOM   3202 O  O   . ARG B 2 168 ? 147.131 151.641 171.137 1.00 16.07  ? 150 ARG B O   1 
ATOM   3203 C  CB  . ARG B 2 168 ? 144.395 151.189 170.033 1.00 12.67  ? 150 ARG B CB  1 
ATOM   3204 C  CG  . ARG B 2 168 ? 143.161 150.793 169.231 1.00 13.32  ? 150 ARG B CG  1 
ATOM   3205 C  CD  . ARG B 2 168 ? 142.872 151.790 168.129 1.00 17.35  ? 150 ARG B CD  1 
ATOM   3206 N  NE  . ARG B 2 168 ? 141.897 151.300 167.165 1.00 11.27  ? 150 ARG B NE  1 
ATOM   3207 C  CZ  . ARG B 2 168 ? 142.199 150.628 166.065 1.00 7.36   ? 150 ARG B CZ  1 
ATOM   3208 N  NH1 . ARG B 2 168 ? 143.443 150.293 165.779 1.00 18.83  ? 150 ARG B NH1 1 
ATOM   3209 N  NH2 . ARG B 2 168 ? 141.228 150.289 165.226 1.00 7.34   ? 150 ARG B NH2 1 
ATOM   3210 N  N   . PHE B 2 169 ? 147.295 152.934 169.298 1.00 19.61  ? 151 PHE B N   1 
ATOM   3211 C  CA  . PHE B 2 169 ? 148.294 153.822 169.876 1.00 14.81  ? 151 PHE B CA  1 
ATOM   3212 C  C   . PHE B 2 169 ? 147.670 154.700 170.952 1.00 15.43  ? 151 PHE B C   1 
ATOM   3213 O  O   . PHE B 2 169 ? 146.652 155.353 170.718 1.00 23.17  ? 151 PHE B O   1 
ATOM   3214 C  CB  . PHE B 2 169 ? 148.895 154.716 168.796 1.00 7.22   ? 151 PHE B CB  1 
ATOM   3215 C  CG  . PHE B 2 169 ? 150.050 154.120 168.050 1.00 8.73   ? 151 PHE B CG  1 
ATOM   3216 C  CD1 . PHE B 2 169 ? 151.332 154.229 168.535 1.00 9.94   ? 151 PHE B CD1 1 
ATOM   3217 C  CD2 . PHE B 2 169 ? 149.859 153.516 166.827 1.00 12.38  ? 151 PHE B CD2 1 
ATOM   3218 C  CE1 . PHE B 2 169 ? 152.389 153.710 167.833 1.00 6.28   ? 151 PHE B CE1 1 
ATOM   3219 C  CE2 . PHE B 2 169 ? 150.915 153.000 166.126 1.00 6.67   ? 151 PHE B CE2 1 
ATOM   3220 C  CZ  . PHE B 2 169 ? 152.177 153.095 166.627 1.00 0.00   ? 151 PHE B CZ  1 
ATOM   3221 N  N   . LEU B 2 170 ? 148.290 154.735 172.129 1.00 12.47  ? 152 LEU B N   1 
ATOM   3222 C  CA  . LEU B 2 170 ? 147.921 155.735 173.125 1.00 19.20  ? 152 LEU B CA  1 
ATOM   3223 C  C   . LEU B 2 170 ? 148.627 157.054 172.844 1.00 27.27  ? 152 LEU B C   1 
ATOM   3224 O  O   . LEU B 2 170 ? 148.002 158.118 172.851 1.00 28.30  ? 152 LEU B O   1 
ATOM   3225 C  CB  . LEU B 2 170 ? 148.264 155.240 174.530 1.00 17.58  ? 152 LEU B CB  1 
ATOM   3226 C  CG  . LEU B 2 170 ? 147.179 154.497 175.298 1.00 16.60  ? 152 LEU B CG  1 
ATOM   3227 C  CD1 . LEU B 2 170 ? 147.043 153.110 174.753 1.00 17.12  ? 152 LEU B CD1 1 
ATOM   3228 C  CD2 . LEU B 2 170 ? 147.517 154.450 176.763 1.00 21.16  ? 152 LEU B CD2 1 
ATOM   3229 N  N   . ASP B 2 171 ? 149.930 156.994 172.606 1.00 25.38  ? 153 ASP B N   1 
ATOM   3230 C  CA  . ASP B 2 171 ? 150.715 158.124 172.141 1.00 17.51  ? 153 ASP B CA  1 
ATOM   3231 C  C   . ASP B 2 171 ? 151.849 157.561 171.291 1.00 22.80  ? 153 ASP B C   1 
ATOM   3232 O  O   . ASP B 2 171 ? 151.783 156.417 170.833 1.00 31.00  ? 153 ASP B O   1 
ATOM   3233 C  CB  . ASP B 2 171 ? 151.163 158.995 173.331 1.00 20.01  ? 153 ASP B CB  1 
ATOM   3234 C  CG  . ASP B 2 171 ? 152.250 158.357 174.166 1.00 30.97  ? 153 ASP B CG  1 
ATOM   3235 O  OD1 . ASP B 2 171 ? 153.348 158.100 173.638 1.00 32.91  ? 153 ASP B OD1 1 
ATOM   3236 O  OD2 . ASP B 2 171 ? 152.024 158.152 175.375 1.00 34.83  ? 153 ASP B OD2 1 
ATOM   3237 N  N   . ASP B 2 172 ? 152.883 158.364 171.056 1.00 24.83  ? 154 ASP B N   1 
ATOM   3238 C  CA  . ASP B 2 172 ? 153.990 157.925 170.215 1.00 25.32  ? 154 ASP B CA  1 
ATOM   3239 C  C   . ASP B 2 172 ? 154.880 156.887 170.886 1.00 26.30  ? 154 ASP B C   1 
ATOM   3240 O  O   . ASP B 2 172 ? 155.723 156.294 170.209 1.00 27.79  ? 154 ASP B O   1 
ATOM   3241 C  CB  . ASP B 2 172 ? 154.837 159.129 169.797 1.00 24.09  ? 154 ASP B CB  1 
ATOM   3242 C  CG  . ASP B 2 172 ? 154.531 159.599 168.392 1.00 30.27  ? 154 ASP B CG  1 
ATOM   3243 O  OD1 . ASP B 2 172 ? 153.546 159.118 167.797 1.00 34.76  ? 154 ASP B OD1 1 
ATOM   3244 O  OD2 . ASP B 2 172 ? 155.278 160.453 167.879 1.00 31.44  ? 154 ASP B OD2 1 
ATOM   3245 N  N   . ASN B 2 173 ? 154.722 156.654 172.187 1.00 25.84  ? 155 ASN B N   1 
ATOM   3246 C  CA  . ASN B 2 173 ? 155.579 155.734 172.915 1.00 23.20  ? 155 ASN B CA  1 
ATOM   3247 C  C   . ASN B 2 173 ? 154.838 154.585 173.582 1.00 30.36  ? 155 ASN B C   1 
ATOM   3248 O  O   . ASN B 2 173 ? 155.492 153.677 174.102 1.00 33.04  ? 155 ASN B O   1 
ATOM   3249 C  CB  . ASN B 2 173 ? 156.384 156.490 173.981 1.00 27.95  ? 155 ASN B CB  1 
ATOM   3250 C  CG  . ASN B 2 173 ? 157.543 155.680 174.516 1.00 36.20  ? 155 ASN B CG  1 
ATOM   3251 O  OD1 . ASN B 2 173 ? 158.508 155.411 173.805 1.00 35.42  ? 155 ASN B OD1 1 
ATOM   3252 N  ND2 . ASN B 2 173 ? 157.451 155.283 175.778 1.00 30.24  ? 155 ASN B ND2 1 
ATOM   3253 N  N   . GLN B 2 174 ? 153.510 154.585 173.586 1.00 30.91  ? 156 GLN B N   1 
ATOM   3254 C  CA  . GLN B 2 174 ? 152.741 153.516 174.198 1.00 20.79  ? 156 GLN B CA  1 
ATOM   3255 C  C   . GLN B 2 174 ? 151.735 152.972 173.200 1.00 23.96  ? 156 GLN B C   1 
ATOM   3256 O  O   . GLN B 2 174 ? 151.226 153.704 172.352 1.00 27.11  ? 156 GLN B O   1 
ATOM   3257 C  CB  . GLN B 2 174 ? 152.018 153.995 175.450 1.00 18.34  ? 156 GLN B CB  1 
ATOM   3258 C  CG  . GLN B 2 174 ? 152.875 154.854 176.344 1.00 23.33  ? 156 GLN B CG  1 
ATOM   3259 C  CD  . GLN B 2 174 ? 152.749 154.478 177.793 1.00 32.58  ? 156 GLN B CD  1 
ATOM   3260 O  OE1 . GLN B 2 174 ? 151.713 154.700 178.414 1.00 35.54  ? 156 GLN B OE1 1 
ATOM   3261 N  NE2 . GLN B 2 174 ? 153.804 153.893 178.344 1.00 33.07  ? 156 GLN B NE2 1 
ATOM   3262 N  N   . ILE B 2 175 ? 151.458 151.678 173.305 1.00 18.42  ? 157 ILE B N   1 
ATOM   3263 C  CA  . ILE B 2 175 ? 150.510 151.013 172.420 1.00 16.08  ? 157 ILE B CA  1 
ATOM   3264 C  C   . ILE B 2 175 ? 149.880 149.851 173.177 1.00 14.62  ? 157 ILE B C   1 
ATOM   3265 O  O   . ILE B 2 175 ? 150.546 149.162 173.953 1.00 19.15  ? 157 ILE B O   1 
ATOM   3266 C  CB  . ILE B 2 175 ? 151.195 150.566 171.107 1.00 9.19   ? 157 ILE B CB  1 
ATOM   3267 C  CG1 . ILE B 2 175 ? 150.176 150.017 170.115 1.00 1.24   ? 157 ILE B CG1 1 
ATOM   3268 C  CG2 . ILE B 2 175 ? 152.284 149.559 171.373 1.00 24.66  ? 157 ILE B CG2 1 
ATOM   3269 C  CD1 . ILE B 2 175 ? 150.745 149.686 168.791 1.00 3.48   ? 157 ILE B CD1 1 
ATOM   3270 N  N   . VAL B 2 176 ? 148.581 149.656 172.972 1.00 15.59  ? 158 VAL B N   1 
ATOM   3271 C  CA  . VAL B 2 176 ? 147.833 148.555 173.564 1.00 19.71  ? 158 VAL B CA  1 
ATOM   3272 C  C   . VAL B 2 176 ? 147.543 147.549 172.463 1.00 20.19  ? 158 VAL B C   1 
ATOM   3273 O  O   . VAL B 2 176 ? 147.044 147.919 171.397 1.00 14.55  ? 158 VAL B O   1 
ATOM   3274 C  CB  . VAL B 2 176 ? 146.527 149.038 174.227 1.00 13.22  ? 158 VAL B CB  1 
ATOM   3275 C  CG1 . VAL B 2 176 ? 145.576 147.892 174.417 1.00 15.93  ? 158 VAL B CG1 1 
ATOM   3276 C  CG2 . VAL B 2 176 ? 146.804 149.660 175.566 1.00 16.21  ? 158 VAL B CG2 1 
ATOM   3277 N  N   . THR B 2 177 ? 147.863 146.284 172.713 1.00 20.48  ? 159 THR B N   1 
ATOM   3278 C  CA  . THR B 2 177 ? 147.587 145.209 171.773 1.00 16.55  ? 159 THR B CA  1 
ATOM   3279 C  C   . THR B 2 177 ? 146.681 144.170 172.418 1.00 7.34   ? 159 THR B C   1 
ATOM   3280 O  O   . THR B 2 177 ? 146.627 144.035 173.639 1.00 12.03  ? 159 THR B O   1 
ATOM   3281 C  CB  . THR B 2 177 ? 148.878 144.533 171.280 1.00 21.15  ? 159 THR B CB  1 
ATOM   3282 O  OG1 . THR B 2 177 ? 149.458 143.764 172.336 1.00 27.47  ? 159 THR B OG1 1 
ATOM   3283 C  CG2 . THR B 2 177 ? 149.883 145.561 170.810 1.00 17.90  ? 159 THR B CG2 1 
ATOM   3284 N  N   . SER B 2 178 ? 145.952 143.446 171.575 1.00 10.70  ? 160 SER B N   1 
ATOM   3285 C  CA  . SER B 2 178 ? 145.128 142.323 171.996 1.00 9.30   ? 160 SER B CA  1 
ATOM   3286 C  C   . SER B 2 178 ? 145.479 141.115 171.148 1.00 11.95  ? 160 SER B C   1 
ATOM   3287 O  O   . SER B 2 178 ? 145.731 141.241 169.949 1.00 6.92   ? 160 SER B O   1 
ATOM   3288 C  CB  . SER B 2 178 ? 143.638 142.632 171.873 1.00 9.89   ? 160 SER B CB  1 
ATOM   3289 O  OG  . SER B 2 178 ? 143.268 142.844 170.532 1.00 4.59   ? 160 SER B OG  1 
ATOM   3290 N  N   . SER B 2 179 ? 145.490 139.945 171.767 1.00 15.67  ? 161 SER B N   1 
ATOM   3291 C  CA  . SER B 2 179 ? 146.006 138.753 171.120 1.00 7.21   ? 161 SER B CA  1 
ATOM   3292 C  C   . SER B 2 179 ? 144.997 137.623 171.214 1.00 9.48   ? 161 SER B C   1 
ATOM   3293 O  O   . SER B 2 179 ? 144.063 137.657 172.014 1.00 15.18  ? 161 SER B O   1 
ATOM   3294 C  CB  . SER B 2 179 ? 147.333 138.320 171.741 1.00 10.48  ? 161 SER B CB  1 
ATOM   3295 O  OG  . SER B 2 179 ? 147.818 137.134 171.145 1.00 18.34  ? 161 SER B OG  1 
ATOM   3296 N  N   . GLY B 2 180 ? 145.204 136.619 170.377 1.00 5.50   ? 162 GLY B N   1 
ATOM   3297 C  CA  . GLY B 2 180 ? 144.435 135.399 170.407 1.00 7.26   ? 162 GLY B CA  1 
ATOM   3298 C  C   . GLY B 2 180 ? 144.805 134.434 171.505 1.00 11.00  ? 162 GLY B C   1 
ATOM   3299 O  O   . GLY B 2 180 ? 144.171 133.388 171.629 1.00 12.87  ? 162 GLY B O   1 
ATOM   3300 N  N   . ASP B 2 181 ? 145.819 134.743 172.309 1.00 13.50  ? 163 ASP B N   1 
ATOM   3301 C  CA  . ASP B 2 181 ? 146.151 133.957 173.485 1.00 9.75   ? 163 ASP B CA  1 
ATOM   3302 C  C   . ASP B 2 181 ? 145.359 134.385 174.715 1.00 16.29  ? 163 ASP B C   1 
ATOM   3303 O  O   . ASP B 2 181 ? 145.762 134.068 175.839 1.00 14.10  ? 163 ASP B O   1 
ATOM   3304 C  CB  . ASP B 2 181 ? 147.653 134.027 173.763 1.00 7.23   ? 163 ASP B CB  1 
ATOM   3305 C  CG  . ASP B 2 181 ? 148.122 135.413 174.150 1.00 14.36  ? 163 ASP B CG  1 
ATOM   3306 O  OD1 . ASP B 2 181 ? 147.320 136.356 174.127 1.00 21.09  ? 163 ASP B OD1 1 
ATOM   3307 O  OD2 . ASP B 2 181 ? 149.313 135.565 174.478 1.00 21.84  ? 163 ASP B OD2 1 
ATOM   3308 N  N   . THR B 2 182 ? 144.250 135.105 174.516 1.00 11.27  ? 164 THR B N   1 
ATOM   3309 C  CA  . THR B 2 182 ? 143.306 135.509 175.561 1.00 17.14  ? 164 THR B CA  1 
ATOM   3310 C  C   . THR B 2 182 ? 143.875 136.565 176.506 1.00 18.31  ? 164 THR B C   1 
ATOM   3311 O  O   . THR B 2 182 ? 143.540 136.583 177.690 1.00 22.59  ? 164 THR B O   1 
ATOM   3312 C  CB  . THR B 2 182 ? 142.800 134.306 176.367 1.00 15.14  ? 164 THR B CB  1 
ATOM   3313 O  OG1 . THR B 2 182 ? 143.840 133.830 177.226 1.00 17.49  ? 164 THR B OG1 1 
ATOM   3314 C  CG2 . THR B 2 182 ? 142.367 133.179 175.450 1.00 5.04   ? 164 THR B CG2 1 
ATOM   3315 N  N   . THR B 2 183 ? 144.720 137.467 176.009 1.00 11.59  ? 165 THR B N   1 
ATOM   3316 C  CA  . THR B 2 183 ? 145.314 138.504 176.843 1.00 9.98   ? 165 THR B CA  1 
ATOM   3317 C  C   . THR B 2 183 ? 145.370 139.819 176.080 1.00 14.22  ? 165 THR B C   1 
ATOM   3318 O  O   . THR B 2 183 ? 145.351 139.848 174.850 1.00 12.73  ? 165 THR B O   1 
ATOM   3319 C  CB  . THR B 2 183 ? 146.735 138.143 177.307 1.00 14.52  ? 165 THR B CB  1 
ATOM   3320 O  OG1 . THR B 2 183 ? 147.517 137.730 176.183 1.00 22.43  ? 165 THR B OG1 1 
ATOM   3321 C  CG2 . THR B 2 183 ? 146.709 137.034 178.331 1.00 18.80  ? 165 THR B CG2 1 
ATOM   3322 N  N   . CYS B 2 184 ? 145.437 140.914 176.833 1.00 24.81  ? 166 CYS B N   1 
ATOM   3323 C  CA  . CYS B 2 184 ? 145.775 142.219 176.289 1.00 15.97  ? 166 CYS B CA  1 
ATOM   3324 C  C   . CYS B 2 184 ? 147.072 142.694 176.931 1.00 19.69  ? 166 CYS B C   1 
ATOM   3325 O  O   . CYS B 2 184 ? 147.469 142.208 177.987 1.00 24.41  ? 166 CYS B O   1 
ATOM   3326 C  CB  . CYS B 2 184 ? 144.660 143.240 176.530 1.00 20.76  ? 166 CYS B CB  1 
ATOM   3327 S  SG  . CYS B 2 184 ? 143.044 142.800 175.868 1.00 30.86  ? 166 CYS B SG  1 
ATOM   3328 N  N   . ALA B 2 185 ? 147.739 143.653 176.295 1.00 22.59  ? 167 ALA B N   1 
ATOM   3329 C  CA  . ALA B 2 185 ? 149.032 144.098 176.796 1.00 18.15  ? 167 ALA B CA  1 
ATOM   3330 C  C   . ALA B 2 185 ? 149.254 145.570 176.486 1.00 25.51  ? 167 ALA B C   1 
ATOM   3331 O  O   . ALA B 2 185 ? 148.750 146.092 175.491 1.00 23.27  ? 167 ALA B O   1 
ATOM   3332 C  CB  . ALA B 2 185 ? 150.170 143.271 176.199 1.00 10.69  ? 167 ALA B CB  1 
ATOM   3333 N  N   . LEU B 2 186 ? 150.026 146.228 177.349 1.00 25.90  ? 168 LEU B N   1 
ATOM   3334 C  CA  . LEU B 2 186 ? 150.483 147.596 177.131 1.00 18.41  ? 168 LEU B CA  1 
ATOM   3335 C  C   . LEU B 2 186 ? 151.997 147.588 176.979 1.00 22.02  ? 168 LEU B C   1 
ATOM   3336 O  O   . LEU B 2 186 ? 152.699 146.997 177.802 1.00 26.03  ? 168 LEU B O   1 
ATOM   3337 C  CB  . LEU B 2 186 ? 150.070 148.507 178.288 1.00 19.73  ? 168 LEU B CB  1 
ATOM   3338 C  CG  . LEU B 2 186 ? 150.572 149.951 178.278 1.00 22.75  ? 168 LEU B CG  1 
ATOM   3339 C  CD1 . LEU B 2 186 ? 149.741 150.810 177.359 1.00 18.01  ? 168 LEU B CD1 1 
ATOM   3340 C  CD2 . LEU B 2 186 ? 150.562 150.525 179.674 1.00 24.23  ? 168 LEU B CD2 1 
ATOM   3341 N  N   . TRP B 2 187 ? 152.498 148.239 175.936 1.00 22.59  ? 169 TRP B N   1 
ATOM   3342 C  CA  . TRP B 2 187 ? 153.903 148.153 175.573 1.00 19.24  ? 169 TRP B CA  1 
ATOM   3343 C  C   . TRP B 2 187 ? 154.620 149.475 175.808 1.00 28.61  ? 169 TRP B C   1 
ATOM   3344 O  O   . TRP B 2 187 ? 154.018 150.495 176.142 1.00 31.77  ? 169 TRP B O   1 
ATOM   3345 C  CB  . TRP B 2 187 ? 154.059 147.735 174.110 1.00 15.73  ? 169 TRP B CB  1 
ATOM   3346 C  CG  . TRP B 2 187 ? 153.510 146.393 173.792 1.00 19.10  ? 169 TRP B CG  1 
ATOM   3347 C  CD1 . TRP B 2 187 ? 152.230 146.094 173.455 1.00 20.37  ? 169 TRP B CD1 1 
ATOM   3348 C  CD2 . TRP B 2 187 ? 154.231 145.161 173.759 1.00 24.71  ? 169 TRP B CD2 1 
ATOM   3349 N  NE1 . TRP B 2 187 ? 152.102 144.751 173.223 1.00 20.98  ? 169 TRP B NE1 1 
ATOM   3350 C  CE2 . TRP B 2 187 ? 153.321 144.155 173.401 1.00 23.61  ? 169 TRP B CE2 1 
ATOM   3351 C  CE3 . TRP B 2 187 ? 155.561 144.811 173.999 1.00 22.40  ? 169 TRP B CE3 1 
ATOM   3352 C  CZ2 . TRP B 2 187 ? 153.694 142.826 173.280 1.00 20.66  ? 169 TRP B CZ2 1 
ATOM   3353 C  CZ3 . TRP B 2 187 ? 155.926 143.495 173.875 1.00 20.76  ? 169 TRP B CZ3 1 
ATOM   3354 C  CH2 . TRP B 2 187 ? 154.998 142.518 173.519 1.00 21.36  ? 169 TRP B CH2 1 
ATOM   3355 N  N   . ASP B 2 188 ? 155.937 149.434 175.622 1.00 35.87  ? 170 ASP B N   1 
ATOM   3356 C  CA  . ASP B 2 188 ? 156.808 150.605 175.699 1.00 31.58  ? 170 ASP B CA  1 
ATOM   3357 C  C   . ASP B 2 188 ? 157.729 150.545 174.486 1.00 34.00  ? 170 ASP B C   1 
ATOM   3358 O  O   . ASP B 2 188 ? 158.709 149.799 174.485 1.00 44.17  ? 170 ASP B O   1 
ATOM   3359 C  CB  . ASP B 2 188 ? 157.597 150.622 177.000 1.00 33.81  ? 170 ASP B CB  1 
ATOM   3360 C  CG  . ASP B 2 188 ? 158.355 151.912 177.205 1.00 40.47  ? 170 ASP B CG  1 
ATOM   3361 O  OD1 . ASP B 2 188 ? 158.291 152.791 176.323 1.00 37.99  ? 170 ASP B OD1 1 
ATOM   3362 O  OD2 . ASP B 2 188 ? 159.009 152.057 178.256 1.00 45.70  ? 170 ASP B OD2 1 
ATOM   3363 N  N   . ILE B 2 189 ? 157.420 151.335 173.459 1.00 28.98  ? 171 ILE B N   1 
ATOM   3364 C  CA  . ILE B 2 189 ? 158.087 151.171 172.172 1.00 27.80  ? 171 ILE B CA  1 
ATOM   3365 C  C   . ILE B 2 189 ? 159.563 151.541 172.249 1.00 34.77  ? 171 ILE B C   1 
ATOM   3366 O  O   . ILE B 2 189 ? 160.382 150.995 171.501 1.00 36.86  ? 171 ILE B O   1 
ATOM   3367 C  CB  . ILE B 2 189 ? 157.348 151.981 171.095 1.00 29.07  ? 171 ILE B CB  1 
ATOM   3368 C  CG1 . ILE B 2 189 ? 155.839 151.816 171.264 1.00 29.57  ? 171 ILE B CG1 1 
ATOM   3369 C  CG2 . ILE B 2 189 ? 157.768 151.529 169.720 1.00 30.18  ? 171 ILE B CG2 1 
ATOM   3370 C  CD1 . ILE B 2 189 ? 155.039 152.181 170.048 1.00 25.84  ? 171 ILE B CD1 1 
ATOM   3371 N  N   . GLU B 2 190 ? 159.937 152.463 173.139 1.00 41.23  ? 172 GLU B N   1 
ATOM   3372 C  CA  . GLU B 2 190 ? 161.343 152.843 173.257 1.00 38.19  ? 172 GLU B CA  1 
ATOM   3373 C  C   . GLU B 2 190 ? 162.206 151.662 173.677 1.00 43.12  ? 172 GLU B C   1 
ATOM   3374 O  O   . GLU B 2 190 ? 163.297 151.460 173.134 1.00 48.47  ? 172 GLU B O   1 
ATOM   3375 C  CB  . GLU B 2 190 ? 161.498 153.992 174.250 1.00 39.01  ? 172 GLU B CB  1 
ATOM   3376 C  CG  . GLU B 2 190 ? 161.924 155.302 173.614 1.00 45.68  ? 172 GLU B CG  1 
ATOM   3377 C  CD  . GLU B 2 190 ? 161.980 156.446 174.609 1.00 50.30  ? 172 GLU B CD  1 
ATOM   3378 O  OE1 . GLU B 2 190 ? 161.500 156.271 175.748 1.00 48.28  ? 172 GLU B OE1 1 
ATOM   3379 O  OE2 . GLU B 2 190 ? 162.499 157.522 174.249 1.00 46.89  ? 172 GLU B OE2 1 
ATOM   3380 N  N   . THR B 2 191 ? 161.739 150.870 174.642 1.00 43.91  ? 173 THR B N   1 
ATOM   3381 C  CA  . THR B 2 191 ? 162.464 149.694 175.100 1.00 41.98  ? 173 THR B CA  1 
ATOM   3382 C  C   . THR B 2 191 ? 161.913 148.391 174.541 1.00 41.48  ? 173 THR B C   1 
ATOM   3383 O  O   . THR B 2 191 ? 162.591 147.365 174.632 1.00 46.04  ? 173 THR B O   1 
ATOM   3384 C  CB  . THR B 2 191 ? 162.457 149.620 176.630 1.00 44.78  ? 173 THR B CB  1 
ATOM   3385 O  OG1 . THR B 2 191 ? 161.302 148.897 177.067 1.00 43.14  ? 173 THR B OG1 1 
ATOM   3386 C  CG2 . THR B 2 191 ? 162.429 151.008 177.229 1.00 46.10  ? 173 THR B CG2 1 
ATOM   3387 N  N   . GLY B 2 192 ? 160.715 148.403 173.970 1.00 40.37  ? 174 GLY B N   1 
ATOM   3388 C  CA  . GLY B 2 192 ? 160.140 147.201 173.397 1.00 39.42  ? 174 GLY B CA  1 
ATOM   3389 C  C   . GLY B 2 192 ? 159.800 146.125 174.401 1.00 37.31  ? 174 GLY B C   1 
ATOM   3390 O  O   . GLY B 2 192 ? 159.958 144.936 174.102 1.00 38.65  ? 174 GLY B O   1 
ATOM   3391 N  N   . GLN B 2 193 ? 159.323 146.507 175.581 1.00 37.08  ? 175 GLN B N   1 
ATOM   3392 C  CA  . GLN B 2 193 ? 158.978 145.563 176.631 1.00 35.64  ? 175 GLN B CA  1 
ATOM   3393 C  C   . GLN B 2 193 ? 157.539 145.779 177.068 1.00 36.36  ? 175 GLN B C   1 
ATOM   3394 O  O   . GLN B 2 193 ? 157.027 146.898 177.036 1.00 38.98  ? 175 GLN B O   1 
ATOM   3395 C  CB  . GLN B 2 193 ? 159.906 145.702 177.847 1.00 35.87  ? 175 GLN B CB  1 
ATOM   3396 C  CG  . GLN B 2 193 ? 161.321 145.191 177.629 1.00 40.74  ? 175 GLN B CG  1 
ATOM   3397 C  CD  . GLN B 2 193 ? 161.365 143.719 177.278 1.00 48.52  ? 175 GLN B CD  1 
ATOM   3398 O  OE1 . GLN B 2 193 ? 160.481 142.950 177.656 1.00 46.56  ? 175 GLN B OE1 1 
ATOM   3399 N  NE2 . GLN B 2 193 ? 162.396 143.318 176.544 1.00 45.42  ? 175 GLN B NE2 1 
ATOM   3400 N  N   . GLN B 2 194 ? 156.890 144.693 177.475 1.00 29.55  ? 176 GLN B N   1 
ATOM   3401 C  CA  . GLN B 2 194 ? 155.554 144.784 178.045 1.00 28.00  ? 176 GLN B CA  1 
ATOM   3402 C  C   . GLN B 2 194 ? 155.615 145.461 179.404 1.00 28.83  ? 176 GLN B C   1 
ATOM   3403 O  O   . GLN B 2 194 ? 156.464 145.131 180.236 1.00 32.38  ? 176 GLN B O   1 
ATOM   3404 C  CB  . GLN B 2 194 ? 154.946 143.394 178.190 1.00 25.72  ? 176 GLN B CB  1 
ATOM   3405 C  CG  . GLN B 2 194 ? 153.853 143.061 177.215 1.00 29.83  ? 176 GLN B CG  1 
ATOM   3406 C  CD  . GLN B 2 194 ? 153.594 141.578 177.160 1.00 37.79  ? 176 GLN B CD  1 
ATOM   3407 O  OE1 . GLN B 2 194 ? 154.273 140.802 177.821 1.00 34.51  ? 176 GLN B OE1 1 
ATOM   3408 N  NE2 . GLN B 2 194 ? 152.616 141.173 176.369 1.00 36.34  ? 176 GLN B NE2 1 
ATOM   3409 N  N   . THR B 2 195 ? 154.708 146.404 179.636 1.00 26.14  ? 177 THR B N   1 
ATOM   3410 C  CA  . THR B 2 195 ? 154.599 147.064 180.929 1.00 26.78  ? 177 THR B CA  1 
ATOM   3411 C  C   . THR B 2 195 ? 153.530 146.440 181.812 1.00 30.42  ? 177 THR B C   1 
ATOM   3412 O  O   . THR B 2 195 ? 153.770 146.216 183.002 1.00 36.23  ? 177 THR B O   1 
ATOM   3413 C  CB  . THR B 2 195 ? 154.311 148.554 180.740 1.00 29.82  ? 177 THR B CB  1 
ATOM   3414 O  OG1 . THR B 2 195 ? 155.467 149.193 180.189 1.00 31.96  ? 177 THR B OG1 1 
ATOM   3415 C  CG2 . THR B 2 195 ? 153.977 149.208 182.064 1.00 30.97  ? 177 THR B CG2 1 
ATOM   3416 N  N   . THR B 2 196 ? 152.360 146.134 181.258 1.00 26.91  ? 178 THR B N   1 
ATOM   3417 C  CA  . THR B 2 196 ? 151.330 145.442 182.014 1.00 28.77  ? 178 THR B CA  1 
ATOM   3418 C  C   . THR B 2 196 ? 150.541 144.531 181.089 1.00 25.71  ? 178 THR B C   1 
ATOM   3419 O  O   . THR B 2 196 ? 150.450 144.766 179.881 1.00 28.55  ? 178 THR B O   1 
ATOM   3420 C  CB  . THR B 2 196 ? 150.392 146.419 182.731 1.00 28.32  ? 178 THR B CB  1 
ATOM   3421 O  OG1 . THR B 2 196 ? 149.767 147.276 181.770 1.00 32.16  ? 178 THR B OG1 1 
ATOM   3422 C  CG2 . THR B 2 196 ? 151.146 147.253 183.726 1.00 26.03  ? 178 THR B CG2 1 
ATOM   3423 N  N   . THR B 2 197 ? 149.980 143.478 181.679 1.00 20.40  ? 179 THR B N   1 
ATOM   3424 C  CA  . THR B 2 197 ? 149.189 142.479 180.979 1.00 24.56  ? 179 THR B CA  1 
ATOM   3425 C  C   . THR B 2 197 ? 147.810 142.393 181.614 1.00 24.81  ? 179 THR B C   1 
ATOM   3426 O  O   . THR B 2 197 ? 147.676 142.430 182.839 1.00 27.49  ? 179 THR B O   1 
ATOM   3427 C  CB  . THR B 2 197 ? 149.866 141.112 181.020 1.00 28.84  ? 179 THR B CB  1 
ATOM   3428 O  OG1 . THR B 2 197 ? 151.139 141.195 180.375 1.00 28.95  ? 179 THR B OG1 1 
ATOM   3429 C  CG2 . THR B 2 197 ? 149.021 140.082 180.306 1.00 27.50  ? 179 THR B CG2 1 
ATOM   3430 N  N   . PHE B 2 198 ? 146.790 142.283 180.772 1.00 24.20  ? 180 PHE B N   1 
ATOM   3431 C  CA  . PHE B 2 198 ? 145.393 142.261 181.185 1.00 20.11  ? 180 PHE B CA  1 
ATOM   3432 C  C   . PHE B 2 198 ? 144.840 140.881 180.858 1.00 29.13  ? 180 PHE B C   1 
ATOM   3433 O  O   . PHE B 2 198 ? 144.585 140.571 179.687 1.00 30.49  ? 180 PHE B O   1 
ATOM   3434 C  CB  . PHE B 2 198 ? 144.606 143.360 180.478 1.00 24.06  ? 180 PHE B CB  1 
ATOM   3435 C  CG  . PHE B 2 198 ? 145.264 144.713 180.526 1.00 25.46  ? 180 PHE B CG  1 
ATOM   3436 C  CD1 . PHE B 2 198 ? 145.094 145.541 181.614 1.00 28.74  ? 180 PHE B CD1 1 
ATOM   3437 C  CD2 . PHE B 2 198 ? 146.037 145.159 179.478 1.00 22.05  ? 180 PHE B CD2 1 
ATOM   3438 C  CE1 . PHE B 2 198 ? 145.687 146.774 181.653 1.00 25.78  ? 180 PHE B CE1 1 
ATOM   3439 C  CE2 . PHE B 2 198 ? 146.634 146.392 179.521 1.00 21.42  ? 180 PHE B CE2 1 
ATOM   3440 C  CZ  . PHE B 2 198 ? 146.458 147.198 180.607 1.00 22.19  ? 180 PHE B CZ  1 
ATOM   3441 N  N   . THR B 2 199 ? 144.662 140.056 181.894 1.00 26.82  ? 181 THR B N   1 
ATOM   3442 C  CA  . THR B 2 199 ? 144.385 138.622 181.760 1.00 26.46  ? 181 THR B CA  1 
ATOM   3443 C  C   . THR B 2 199 ? 143.155 138.255 182.584 1.00 24.04  ? 181 THR B C   1 
ATOM   3444 O  O   . THR B 2 199 ? 143.273 137.962 183.774 1.00 27.69  ? 181 THR B O   1 
ATOM   3445 C  CB  . THR B 2 199 ? 145.589 137.785 182.203 1.00 25.78  ? 181 THR B CB  1 
ATOM   3446 O  OG1 . THR B 2 199 ? 145.642 137.753 183.632 1.00 27.97  ? 181 THR B OG1 1 
ATOM   3447 C  CG2 . THR B 2 199 ? 146.885 138.363 181.686 1.00 27.10  ? 181 THR B CG2 1 
ATOM   3448 N  N   . GLY B 2 200 ? 141.981 138.274 181.960 1.00 28.94  ? 182 GLY B N   1 
ATOM   3449 C  CA  . GLY B 2 200 ? 140.810 137.689 182.581 1.00 22.12  ? 182 GLY B CA  1 
ATOM   3450 C  C   . GLY B 2 200 ? 139.903 136.933 181.633 1.00 24.17  ? 182 GLY B C   1 
ATOM   3451 O  O   . GLY B 2 200 ? 138.985 136.242 182.076 1.00 29.57  ? 182 GLY B O   1 
ATOM   3452 N  N   . HIS B 2 201 ? 140.162 137.027 180.333 1.00 18.61  ? 183 HIS B N   1 
ATOM   3453 C  CA  . HIS B 2 201 ? 139.285 136.438 179.333 1.00 9.64   ? 183 HIS B CA  1 
ATOM   3454 C  C   . HIS B 2 201 ? 139.564 134.948 179.189 1.00 19.83  ? 183 HIS B C   1 
ATOM   3455 O  O   . HIS B 2 201 ? 140.669 134.476 179.463 1.00 32.49  ? 183 HIS B O   1 
ATOM   3456 C  CB  . HIS B 2 201 ? 139.471 137.125 177.979 1.00 9.75   ? 183 HIS B CB  1 
ATOM   3457 C  CG  . HIS B 2 201 ? 138.671 138.381 177.808 1.00 28.11  ? 183 HIS B CG  1 
ATOM   3458 N  ND1 . HIS B 2 201 ? 137.294 138.390 177.771 1.00 24.44  ? 183 HIS B ND1 1 
ATOM   3459 C  CD2 . HIS B 2 201 ? 139.056 139.666 177.639 1.00 19.80  ? 183 HIS B CD2 1 
ATOM   3460 C  CE1 . HIS B 2 201 ? 136.867 139.627 177.596 1.00 10.93  ? 183 HIS B CE1 1 
ATOM   3461 N  NE2 . HIS B 2 201 ? 137.916 140.420 177.514 1.00 12.61  ? 183 HIS B NE2 1 
ATOM   3462 N  N   . THR B 2 202 ? 138.550 134.203 178.750 1.00 15.96  ? 184 THR B N   1 
ATOM   3463 C  CA  . THR B 2 202 ? 138.693 132.774 178.500 1.00 12.18  ? 184 THR B CA  1 
ATOM   3464 C  C   . THR B 2 202 ? 138.534 132.426 177.024 1.00 16.72  ? 184 THR B C   1 
ATOM   3465 O  O   . THR B 2 202 ? 138.285 131.266 176.689 1.00 24.97  ? 184 THR B O   1 
ATOM   3466 C  CB  . THR B 2 202 ? 137.698 131.969 179.339 1.00 21.30  ? 184 THR B CB  1 
ATOM   3467 O  OG1 . THR B 2 202 ? 136.441 131.890 178.659 1.00 30.65  ? 184 THR B OG1 1 
ATOM   3468 C  CG2 . THR B 2 202 ? 137.496 132.604 180.697 1.00 15.89  ? 184 THR B CG2 1 
ATOM   3469 N  N   . GLY B 2 203 ? 138.668 133.409 176.137 1.00 13.75  ? 185 GLY B N   1 
ATOM   3470 C  CA  . GLY B 2 203 ? 138.645 133.170 174.710 1.00 8.24   ? 185 GLY B CA  1 
ATOM   3471 C  C   . GLY B 2 203 ? 139.485 134.221 174.021 1.00 15.61  ? 185 GLY B C   1 
ATOM   3472 O  O   . GLY B 2 203 ? 139.959 135.167 174.649 1.00 26.93  ? 185 GLY B O   1 
ATOM   3473 N  N   . ASP B 2 204 ? 139.673 134.040 172.717 1.00 13.21  ? 186 ASP B N   1 
ATOM   3474 C  CA  . ASP B 2 204 ? 140.409 135.012 171.919 1.00 5.65   ? 186 ASP B CA  1 
ATOM   3475 C  C   . ASP B 2 204 ? 139.827 136.396 172.119 1.00 11.31  ? 186 ASP B C   1 
ATOM   3476 O  O   . ASP B 2 204 ? 138.611 136.566 172.102 1.00 30.07  ? 186 ASP B O   1 
ATOM   3477 C  CB  . ASP B 2 204 ? 140.327 134.654 170.436 1.00 15.38  ? 186 ASP B CB  1 
ATOM   3478 C  CG  . ASP B 2 204 ? 141.239 133.529 170.049 1.00 30.04  ? 186 ASP B CG  1 
ATOM   3479 O  OD1 . ASP B 2 204 ? 141.667 132.769 170.937 1.00 34.64  ? 186 ASP B OD1 1 
ATOM   3480 O  OD2 . ASP B 2 204 ? 141.519 133.400 168.841 1.00 26.29  ? 186 ASP B OD2 1 
ATOM   3481 N  N   . VAL B 2 205 ? 140.688 137.385 172.307 1.00 5.16   ? 187 VAL B N   1 
ATOM   3482 C  CA  . VAL B 2 205 ? 140.252 138.775 172.324 1.00 12.05  ? 187 VAL B CA  1 
ATOM   3483 C  C   . VAL B 2 205 ? 140.221 139.270 170.887 1.00 9.82   ? 187 VAL B C   1 
ATOM   3484 O  O   . VAL B 2 205 ? 141.216 139.169 170.164 1.00 7.74   ? 187 VAL B O   1 
ATOM   3485 C  CB  . VAL B 2 205 ? 141.170 139.640 173.203 1.00 12.00  ? 187 VAL B CB  1 
ATOM   3486 C  CG1 . VAL B 2 205 ? 140.634 141.039 173.295 1.00 9.49   ? 187 VAL B CG1 1 
ATOM   3487 C  CG2 . VAL B 2 205 ? 141.272 139.058 174.577 1.00 0.00   ? 187 VAL B CG2 1 
ATOM   3488 N  N   . MET B 2 206 ? 139.069 139.781 170.463 1.00 6.52   ? 188 MET B N   1 
ATOM   3489 C  CA  . MET B 2 206 ? 138.843 140.110 169.064 1.00 7.70   ? 188 MET B CA  1 
ATOM   3490 C  C   . MET B 2 206 ? 138.972 141.594 168.752 1.00 9.32   ? 188 MET B C   1 
ATOM   3491 O  O   . MET B 2 206 ? 139.400 141.942 167.650 1.00 13.01  ? 188 MET B O   1 
ATOM   3492 C  CB  . MET B 2 206 ? 137.458 139.622 168.631 1.00 15.09  ? 188 MET B CB  1 
ATOM   3493 C  CG  . MET B 2 206 ? 137.244 138.121 168.744 1.00 1.12   ? 188 MET B CG  1 
ATOM   3494 S  SD  . MET B 2 206 ? 138.547 137.150 167.975 1.00 25.44  ? 188 MET B SD  1 
ATOM   3495 C  CE  . MET B 2 206 ? 138.415 137.699 166.285 1.00 8.40   ? 188 MET B CE  1 
ATOM   3496 N  N   . SER B 2 207 ? 138.619 142.477 169.683 1.00 11.11  ? 189 SER B N   1 
ATOM   3497 C  CA  . SER B 2 207 ? 138.683 143.907 169.437 1.00 3.45   ? 189 SER B CA  1 
ATOM   3498 C  C   . SER B 2 207 ? 138.892 144.640 170.752 1.00 9.35   ? 189 SER B C   1 
ATOM   3499 O  O   . SER B 2 207 ? 138.605 144.114 171.826 1.00 22.20  ? 189 SER B O   1 
ATOM   3500 C  CB  . SER B 2 207 ? 137.410 144.409 168.753 1.00 10.35  ? 189 SER B CB  1 
ATOM   3501 O  OG  . SER B 2 207 ? 137.448 145.810 168.552 1.00 23.15  ? 189 SER B OG  1 
ATOM   3502 N  N   . LEU B 2 208 ? 139.400 145.867 170.652 1.00 8.41   ? 190 LEU B N   1 
ATOM   3503 C  CA  . LEU B 2 208 ? 139.533 146.759 171.794 1.00 9.00   ? 190 LEU B CA  1 
ATOM   3504 C  C   . LEU B 2 208 ? 139.255 148.183 171.340 1.00 6.89   ? 190 LEU B C   1 
ATOM   3505 O  O   . LEU B 2 208 ? 139.327 148.502 170.154 1.00 12.89  ? 190 LEU B O   1 
ATOM   3506 C  CB  . LEU B 2 208 ? 140.920 146.657 172.458 1.00 18.22  ? 190 LEU B CB  1 
ATOM   3507 C  CG  . LEU B 2 208 ? 142.204 147.050 171.725 1.00 10.12  ? 190 LEU B CG  1 
ATOM   3508 C  CD1 . LEU B 2 208 ? 142.613 148.467 172.044 1.00 17.49  ? 190 LEU B CD1 1 
ATOM   3509 C  CD2 . LEU B 2 208 ? 143.299 146.132 172.126 1.00 6.76   ? 190 LEU B CD2 1 
ATOM   3510 N  N   . SER B 2 209 ? 138.923 149.040 172.301 1.00 4.91   ? 191 SER B N   1 
ATOM   3511 C  CA  . SER B 2 209 ? 138.531 150.411 172.005 1.00 9.44   ? 191 SER B CA  1 
ATOM   3512 C  C   . SER B 2 209 ? 138.964 151.307 173.151 1.00 10.69  ? 191 SER B C   1 
ATOM   3513 O  O   . SER B 2 209 ? 138.550 151.095 174.291 1.00 19.18  ? 191 SER B O   1 
ATOM   3514 C  CB  . SER B 2 209 ? 137.023 150.508 171.792 1.00 21.36  ? 191 SER B CB  1 
ATOM   3515 O  OG  . SER B 2 209 ? 136.683 151.661 171.046 1.00 26.86  ? 191 SER B OG  1 
ATOM   3516 N  N   . LEU B 2 210 ? 139.772 152.315 172.847 1.00 17.77  ? 192 LEU B N   1 
ATOM   3517 C  CA  . LEU B 2 210 ? 140.286 153.215 173.865 1.00 17.91  ? 192 LEU B CA  1 
ATOM   3518 C  C   . LEU B 2 210 ? 139.271 154.293 174.207 1.00 17.18  ? 192 LEU B C   1 
ATOM   3519 O  O   . LEU B 2 210 ? 138.460 154.700 173.373 1.00 20.88  ? 192 LEU B O   1 
ATOM   3520 C  CB  . LEU B 2 210 ? 141.576 153.874 173.396 1.00 15.52  ? 192 LEU B CB  1 
ATOM   3521 C  CG  . LEU B 2 210 ? 142.869 153.086 173.482 1.00 14.73  ? 192 LEU B CG  1 
ATOM   3522 C  CD1 . LEU B 2 210 ? 143.865 153.713 172.558 1.00 17.58  ? 192 LEU B CD1 1 
ATOM   3523 C  CD2 . LEU B 2 210 ? 143.376 153.103 174.900 1.00 18.30  ? 192 LEU B CD2 1 
ATOM   3524 N  N   . ALA B 2 211 ? 139.333 154.766 175.445 1.00 26.18  ? 193 ALA B N   1 
ATOM   3525 C  CA  . ALA B 2 211 ? 138.449 155.826 175.881 1.00 30.19  ? 193 ALA B CA  1 
ATOM   3526 C  C   . ALA B 2 211 ? 138.878 157.153 175.269 1.00 41.98  ? 193 ALA B C   1 
ATOM   3527 O  O   . ALA B 2 211 ? 140.022 157.307 174.838 1.00 45.95  ? 193 ALA B O   1 
ATOM   3528 C  CB  . ALA B 2 211 ? 138.446 155.929 177.401 1.00 29.88  ? 193 ALA B CB  1 
ATOM   3529 N  N   . PRO B 2 212 ? 137.967 158.126 175.199 1.00 46.69  ? 194 PRO B N   1 
ATOM   3530 C  CA  . PRO B 2 212 ? 138.384 159.472 174.778 1.00 39.98  ? 194 PRO B CA  1 
ATOM   3531 C  C   . PRO B 2 212 ? 139.511 160.043 175.622 1.00 42.02  ? 194 PRO B C   1 
ATOM   3532 O  O   . PRO B 2 212 ? 140.405 160.707 175.086 1.00 43.68  ? 194 PRO B O   1 
ATOM   3533 C  CB  . PRO B 2 212 ? 137.092 160.283 174.918 1.00 40.11  ? 194 PRO B CB  1 
ATOM   3534 C  CG  . PRO B 2 212 ? 136.015 159.289 174.676 1.00 40.26  ? 194 PRO B CG  1 
ATOM   3535 C  CD  . PRO B 2 212 ? 136.500 157.993 175.251 1.00 39.21  ? 194 PRO B CD  1 
ATOM   3536 N  N   . ASP B 2 213 ? 139.502 159.791 176.931 1.00 47.89  ? 195 ASP B N   1 
ATOM   3537 C  CA  . ASP B 2 213 ? 140.565 160.246 177.817 1.00 50.06  ? 195 ASP B CA  1 
ATOM   3538 C  C   . ASP B 2 213 ? 141.758 159.299 177.868 1.00 53.53  ? 195 ASP B C   1 
ATOM   3539 O  O   . ASP B 2 213 ? 142.778 159.653 178.469 1.00 55.75  ? 195 ASP B O   1 
ATOM   3540 C  CB  . ASP B 2 213 ? 140.008 160.446 179.227 1.00 50.50  ? 195 ASP B CB  1 
ATOM   3541 C  CG  . ASP B 2 213 ? 139.453 159.165 179.820 1.00 56.84  ? 195 ASP B CG  1 
ATOM   3542 O  OD1 . ASP B 2 213 ? 139.429 158.137 179.114 1.00 52.73  ? 195 ASP B OD1 1 
ATOM   3543 O  OD2 . ASP B 2 213 ? 139.036 159.184 180.996 1.00 57.79  ? 195 ASP B OD2 1 
ATOM   3544 N  N   . THR B 2 214 ? 141.656 158.118 177.253 1.00 50.02  ? 196 THR B N   1 
ATOM   3545 C  CA  . THR B 2 214 ? 142.725 157.111 177.232 1.00 49.98  ? 196 THR B CA  1 
ATOM   3546 C  C   . THR B 2 214 ? 143.182 156.737 178.638 1.00 46.94  ? 196 THR B C   1 
ATOM   3547 O  O   . THR B 2 214 ? 144.363 156.486 178.880 1.00 44.99  ? 196 THR B O   1 
ATOM   3548 C  CB  . THR B 2 214 ? 143.918 157.563 176.387 1.00 50.40  ? 196 THR B CB  1 
ATOM   3549 O  OG1 . THR B 2 214 ? 144.543 158.695 177.002 1.00 55.37  ? 196 THR B OG1 1 
ATOM   3550 C  CG2 . THR B 2 214 ? 143.475 157.925 174.978 1.00 46.76  ? 196 THR B CG2 1 
ATOM   3551 N  N   . ARG B 2 215 ? 142.236 156.691 179.577 1.00 49.02  ? 197 ARG B N   1 
ATOM   3552 C  CA  . ARG B 2 215 ? 142.499 156.175 180.910 1.00 50.31  ? 197 ARG B CA  1 
ATOM   3553 C  C   . ARG B 2 215 ? 141.949 154.775 181.128 1.00 50.88  ? 197 ARG B C   1 
ATOM   3554 O  O   . ARG B 2 215 ? 142.453 154.060 181.997 1.00 49.96  ? 197 ARG B O   1 
ATOM   3555 C  CB  . ARG B 2 215 ? 141.910 157.110 181.975 1.00 48.18  ? 197 ARG B CB  1 
ATOM   3556 C  CG  . ARG B 2 215 ? 142.708 158.373 182.203 1.00 46.83  ? 197 ARG B CG  1 
ATOM   3557 C  CD  . ARG B 2 215 ? 143.668 158.204 183.361 1.00 52.63  ? 197 ARG B CD  1 
ATOM   3558 N  NE  . ARG B 2 215 ? 142.973 158.134 184.640 1.00 56.91  ? 197 ARG B NE  1 
ATOM   3559 C  CZ  . ARG B 2 215 ? 143.570 158.190 185.822 1.00 54.59  ? 197 ARG B CZ  1 
ATOM   3560 N  NH1 . ARG B 2 215 ? 144.881 158.331 185.928 1.00 53.76  ? 197 ARG B NH1 1 
ATOM   3561 N  NH2 . ARG B 2 215 ? 142.833 158.099 186.926 1.00 50.83  ? 197 ARG B NH2 1 
ATOM   3562 N  N   . LEU B 2 216 ? 140.934 154.374 180.368 1.00 38.82  ? 198 LEU B N   1 
ATOM   3563 C  CA  . LEU B 2 216 ? 140.374 153.035 180.404 1.00 33.51  ? 198 LEU B CA  1 
ATOM   3564 C  C   . LEU B 2 216 ? 140.179 152.551 178.978 1.00 31.46  ? 198 LEU B C   1 
ATOM   3565 O  O   . LEU B 2 216 ? 140.250 153.326 178.024 1.00 39.00  ? 198 LEU B O   1 
ATOM   3566 C  CB  . LEU B 2 216 ? 139.034 152.997 181.150 1.00 37.78  ? 198 LEU B CB  1 
ATOM   3567 C  CG  . LEU B 2 216 ? 138.823 153.852 182.395 1.00 39.02  ? 198 LEU B CG  1 
ATOM   3568 C  CD1 . LEU B 2 216 ? 137.348 154.070 182.615 1.00 36.45  ? 198 LEU B CD1 1 
ATOM   3569 C  CD2 . LEU B 2 216 ? 139.438 153.189 183.601 1.00 35.67  ? 198 LEU B CD2 1 
ATOM   3570 N  N   . PHE B 2 217 ? 139.937 151.253 178.831 1.00 16.25  ? 199 PHE B N   1 
ATOM   3571 C  CA  . PHE B 2 217 ? 139.522 150.723 177.538 1.00 10.61  ? 199 PHE B CA  1 
ATOM   3572 C  C   . PHE B 2 217 ? 138.671 149.485 177.766 1.00 19.12  ? 199 PHE B C   1 
ATOM   3573 O  O   . PHE B 2 217 ? 138.550 148.994 178.883 1.00 22.94  ? 199 PHE B O   1 
ATOM   3574 C  CB  . PHE B 2 217 ? 140.722 150.450 176.607 1.00 14.52  ? 199 PHE B CB  1 
ATOM   3575 C  CG  . PHE B 2 217 ? 141.652 149.365 177.071 1.00 21.53  ? 199 PHE B CG  1 
ATOM   3576 C  CD1 . PHE B 2 217 ? 142.554 149.590 178.089 1.00 22.48  ? 199 PHE B CD1 1 
ATOM   3577 C  CD2 . PHE B 2 217 ? 141.652 148.131 176.453 1.00 20.32  ? 199 PHE B CD2 1 
ATOM   3578 C  CE1 . PHE B 2 217 ? 143.406 148.601 178.500 1.00 15.95  ? 199 PHE B CE1 1 
ATOM   3579 C  CE2 . PHE B 2 217 ? 142.503 147.137 176.863 1.00 16.96  ? 199 PHE B CE2 1 
ATOM   3580 C  CZ  . PHE B 2 217 ? 143.381 147.372 177.883 1.00 16.64  ? 199 PHE B CZ  1 
ATOM   3581 N  N   . VAL B 2 218 ? 138.031 149.017 176.701 1.00 19.57  ? 200 VAL B N   1 
ATOM   3582 C  CA  . VAL B 2 218 ? 137.184 147.834 176.770 1.00 12.20  ? 200 VAL B CA  1 
ATOM   3583 C  C   . VAL B 2 218 ? 137.681 146.820 175.757 1.00 14.64  ? 200 VAL B C   1 
ATOM   3584 O  O   . VAL B 2 218 ? 138.257 147.171 174.726 1.00 15.88  ? 200 VAL B O   1 
ATOM   3585 C  CB  . VAL B 2 218 ? 135.690 148.145 176.525 1.00 14.17  ? 200 VAL B CB  1 
ATOM   3586 C  CG1 . VAL B 2 218 ? 135.058 148.738 177.759 1.00 12.14  ? 200 VAL B CG1 1 
ATOM   3587 C  CG2 . VAL B 2 218 ? 135.514 149.064 175.333 1.00 15.53  ? 200 VAL B CG2 1 
ATOM   3588 N  N   . SER B 2 219 ? 137.454 145.549 176.062 1.00 22.85  ? 201 SER B N   1 
ATOM   3589 C  CA  . SER B 2 219 ? 137.794 144.458 175.162 1.00 8.44   ? 201 SER B CA  1 
ATOM   3590 C  C   . SER B 2 219 ? 136.621 143.500 175.047 1.00 11.97  ? 201 SER B C   1 
ATOM   3591 O  O   . SER B 2 219 ? 135.862 143.309 175.998 1.00 22.10  ? 201 SER B O   1 
ATOM   3592 C  CB  . SER B 2 219 ? 139.023 143.698 175.640 1.00 14.52  ? 201 SER B CB  1 
ATOM   3593 O  OG  . SER B 2 219 ? 138.680 142.800 176.675 1.00 24.03  ? 201 SER B OG  1 
ATOM   3594 N  N   . GLY B 2 220 ? 136.479 142.909 173.871 1.00 7.34   ? 202 GLY B N   1 
ATOM   3595 C  CA  . GLY B 2 220 ? 135.492 141.866 173.636 1.00 10.31  ? 202 GLY B CA  1 
ATOM   3596 C  C   . GLY B 2 220 ? 136.193 140.601 173.187 1.00 17.76  ? 202 GLY B C   1 
ATOM   3597 O  O   . GLY B 2 220 ? 137.196 140.665 172.483 1.00 18.89  ? 202 GLY B O   1 
ATOM   3598 N  N   . ALA B 2 221 ? 135.666 139.451 173.601 1.00 17.79  ? 203 ALA B N   1 
ATOM   3599 C  CA  . ALA B 2 221 ? 136.360 138.195 173.369 1.00 1.67   ? 203 ALA B CA  1 
ATOM   3600 C  C   . ALA B 2 221 ? 135.383 137.120 172.917 1.00 4.43   ? 203 ALA B C   1 
ATOM   3601 O  O   . ALA B 2 221 ? 134.177 137.344 172.812 1.00 15.08  ? 203 ALA B O   1 
ATOM   3602 C  CB  . ALA B 2 221 ? 137.118 137.748 174.617 1.00 4.97   ? 203 ALA B CB  1 
ATOM   3603 N  N   . CYS B 2 222 ? 135.929 135.936 172.650 1.00 10.71  ? 204 CYS B N   1 
ATOM   3604 C  CA  . CYS B 2 222 ? 135.181 134.793 172.150 1.00 13.53  ? 204 CYS B CA  1 
ATOM   3605 C  C   . CYS B 2 222 ? 134.533 133.967 173.255 1.00 15.48  ? 204 CYS B C   1 
ATOM   3606 O  O   . CYS B 2 222 ? 134.177 132.813 173.015 1.00 22.67  ? 204 CYS B O   1 
ATOM   3607 C  CB  . CYS B 2 222 ? 136.090 133.896 171.310 1.00 15.14  ? 204 CYS B CB  1 
ATOM   3608 S  SG  . CYS B 2 222 ? 136.477 134.524 169.673 1.00 24.93  ? 204 CYS B SG  1 
ATOM   3609 N  N   . ASP B 2 223 ? 134.392 134.517 174.456 1.00 19.45  ? 205 ASP B N   1 
ATOM   3610 C  CA  . ASP B 2 223 ? 133.589 133.905 175.503 1.00 13.23  ? 205 ASP B CA  1 
ATOM   3611 C  C   . ASP B 2 223 ? 132.250 134.603 175.682 1.00 17.86  ? 205 ASP B C   1 
ATOM   3612 O  O   . ASP B 2 223 ? 131.558 134.345 176.671 1.00 17.14  ? 205 ASP B O   1 
ATOM   3613 C  CB  . ASP B 2 223 ? 134.354 133.891 176.824 1.00 11.06  ? 205 ASP B CB  1 
ATOM   3614 C  CG  . ASP B 2 223 ? 134.925 135.239 177.180 1.00 24.42  ? 205 ASP B CG  1 
ATOM   3615 O  OD1 . ASP B 2 223 ? 135.150 136.042 176.268 1.00 23.13  ? 205 ASP B OD1 1 
ATOM   3616 O  OD2 . ASP B 2 223 ? 135.150 135.505 178.375 1.00 32.58  ? 205 ASP B OD2 1 
ATOM   3617 N  N   . ALA B 2 224 ? 131.878 135.482 174.747 1.00 11.69  ? 206 ALA B N   1 
ATOM   3618 C  CA  . ALA B 2 224 ? 130.625 136.237 174.788 1.00 5.63   ? 206 ALA B CA  1 
ATOM   3619 C  C   . ALA B 2 224 ? 130.576 137.193 175.977 1.00 27.34  ? 206 ALA B C   1 
ATOM   3620 O  O   . ALA B 2 224 ? 129.534 137.376 176.604 1.00 36.17  ? 206 ALA B O   1 
ATOM   3621 C  CB  . ALA B 2 224 ? 129.413 135.308 174.796 1.00 6.12   ? 206 ALA B CB  1 
ATOM   3622 N  N   . SER B 2 225 ? 131.708 137.819 176.285 1.00 14.38  ? 207 SER B N   1 
ATOM   3623 C  CA  . SER B 2 225 ? 131.779 138.777 177.376 1.00 11.98  ? 207 SER B CA  1 
ATOM   3624 C  C   . SER B 2 225 ? 132.669 139.937 176.964 1.00 21.87  ? 207 SER B C   1 
ATOM   3625 O  O   . SER B 2 225 ? 133.472 139.829 176.037 1.00 25.52  ? 207 SER B O   1 
ATOM   3626 C  CB  . SER B 2 225 ? 132.311 138.141 178.663 1.00 13.01  ? 207 SER B CB  1 
ATOM   3627 O  OG  . SER B 2 225 ? 133.707 138.327 178.783 1.00 18.61  ? 207 SER B OG  1 
ATOM   3628 N  N   . ALA B 2 226 ? 132.508 141.060 177.661 1.00 24.64  ? 208 ALA B N   1 
ATOM   3629 C  CA  . ALA B 2 226 ? 133.343 142.233 177.464 1.00 10.33  ? 208 ALA B CA  1 
ATOM   3630 C  C   . ALA B 2 226 ? 133.843 142.716 178.814 1.00 16.43  ? 208 ALA B C   1 
ATOM   3631 O  O   . ALA B 2 226 ? 133.165 142.569 179.829 1.00 20.81  ? 208 ALA B O   1 
ATOM   3632 C  CB  . ALA B 2 226 ? 132.590 143.352 176.757 1.00 11.92  ? 208 ALA B CB  1 
ATOM   3633 N  N   . LYS B 2 227 ? 135.042 143.282 178.823 1.00 21.79  ? 209 LYS B N   1 
ATOM   3634 C  CA  . LYS B 2 227 ? 135.693 143.662 180.069 1.00 22.69  ? 209 LYS B CA  1 
ATOM   3635 C  C   . LYS B 2 227 ? 136.260 145.068 179.979 1.00 23.17  ? 209 LYS B C   1 
ATOM   3636 O  O   . LYS B 2 227 ? 136.815 145.455 178.947 1.00 27.12  ? 209 LYS B O   1 
ATOM   3637 C  CB  . LYS B 2 227 ? 136.805 142.679 180.432 1.00 14.50  ? 209 LYS B CB  1 
ATOM   3638 C  CG  . LYS B 2 227 ? 136.293 141.324 180.848 1.00 14.30  ? 209 LYS B CG  1 
ATOM   3639 C  CD  . LYS B 2 227 ? 137.406 140.418 181.292 1.00 16.51  ? 209 LYS B CD  1 
ATOM   3640 C  CE  . LYS B 2 227 ? 136.850 139.151 181.900 1.00 21.05  ? 209 LYS B CE  1 
ATOM   3641 N  NZ  . LYS B 2 227 ? 136.138 139.399 183.177 1.00 25.51  ? 209 LYS B NZ  1 
ATOM   3642 N  N   . LEU B 2 228 ? 136.133 145.817 181.075 1.00 20.86  ? 210 LEU B N   1 
ATOM   3643 C  CA  . LEU B 2 228 ? 136.653 147.176 181.175 1.00 25.81  ? 210 LEU B CA  1 
ATOM   3644 C  C   . LEU B 2 228 ? 137.953 147.159 181.969 1.00 25.60  ? 210 LEU B C   1 
ATOM   3645 O  O   . LEU B 2 228 ? 137.980 146.684 183.106 1.00 25.67  ? 210 LEU B O   1 
ATOM   3646 C  CB  . LEU B 2 228 ? 135.631 148.099 181.836 1.00 28.27  ? 210 LEU B CB  1 
ATOM   3647 C  CG  . LEU B 2 228 ? 136.000 149.560 182.092 1.00 26.11  ? 210 LEU B CG  1 
ATOM   3648 C  CD1 . LEU B 2 228 ? 135.835 150.385 180.843 1.00 17.33  ? 210 LEU B CD1 1 
ATOM   3649 C  CD2 . LEU B 2 228 ? 135.150 150.128 183.203 1.00 26.89  ? 210 LEU B CD2 1 
ATOM   3650 N  N   . TRP B 2 229 ? 139.018 147.691 181.375 1.00 29.67  ? 211 TRP B N   1 
ATOM   3651 C  CA  . TRP B 2 229 ? 140.353 147.677 181.950 1.00 22.95  ? 211 TRP B CA  1 
ATOM   3652 C  C   . TRP B 2 229 ? 140.814 149.090 182.271 1.00 34.37  ? 211 TRP B C   1 
ATOM   3653 O  O   . TRP B 2 229 ? 140.608 150.019 181.481 1.00 36.40  ? 211 TRP B O   1 
ATOM   3654 C  CB  . TRP B 2 229 ? 141.358 147.040 180.996 1.00 20.03  ? 211 TRP B CB  1 
ATOM   3655 C  CG  . TRP B 2 229 ? 140.947 145.723 180.469 1.00 29.07  ? 211 TRP B CG  1 
ATOM   3656 C  CD1 . TRP B 2 229 ? 140.355 145.470 179.274 1.00 23.25  ? 211 TRP B CD1 1 
ATOM   3657 C  CD2 . TRP B 2 229 ? 141.107 144.461 181.114 1.00 23.84  ? 211 TRP B CD2 1 
ATOM   3658 N  NE1 . TRP B 2 229 ? 140.131 144.127 179.133 1.00 22.42  ? 211 TRP B NE1 1 
ATOM   3659 C  CE2 . TRP B 2 229 ? 140.586 143.485 180.253 1.00 25.29  ? 211 TRP B CE2 1 
ATOM   3660 C  CE3 . TRP B 2 229 ? 141.640 144.063 182.340 1.00 19.69  ? 211 TRP B CE3 1 
ATOM   3661 C  CZ2 . TRP B 2 229 ? 140.576 142.139 180.578 1.00 27.63  ? 211 TRP B CZ2 1 
ATOM   3662 C  CZ3 . TRP B 2 229 ? 141.631 142.732 182.658 1.00 26.00  ? 211 TRP B CZ3 1 
ATOM   3663 C  CH2 . TRP B 2 229 ? 141.102 141.784 181.784 1.00 26.47  ? 211 TRP B CH2 1 
ATOM   3664 N  N   . ASP B 2 230 ? 141.455 149.226 183.428 1.00 48.08  ? 212 ASP B N   1 
ATOM   3665 C  CA  . ASP B 2 230 ? 142.099 150.460 183.853 1.00 46.03  ? 212 ASP B CA  1 
ATOM   3666 C  C   . ASP B 2 230 ? 143.570 150.403 183.458 1.00 48.37  ? 212 ASP B C   1 
ATOM   3667 O  O   . ASP B 2 230 ? 144.315 149.555 183.955 1.00 50.38  ? 212 ASP B O   1 
ATOM   3668 C  CB  . ASP B 2 230 ? 141.943 150.636 185.362 1.00 50.28  ? 212 ASP B CB  1 
ATOM   3669 C  CG  . ASP B 2 230 ? 142.630 151.874 185.883 1.00 53.31  ? 212 ASP B CG  1 
ATOM   3670 O  OD1 . ASP B 2 230 ? 143.850 151.821 186.118 1.00 52.72  ? 212 ASP B OD1 1 
ATOM   3671 O  OD2 . ASP B 2 230 ? 141.950 152.900 186.076 1.00 55.12  ? 212 ASP B OD2 1 
ATOM   3672 N  N   . VAL B 2 231 ? 143.984 151.300 182.561 1.00 50.71  ? 213 VAL B N   1 
ATOM   3673 C  CA  . VAL B 2 231 ? 145.319 151.212 181.975 1.00 51.90  ? 213 VAL B CA  1 
ATOM   3674 C  C   . VAL B 2 231 ? 146.393 151.417 183.033 1.00 52.29  ? 213 VAL B C   1 
ATOM   3675 O  O   . VAL B 2 231 ? 147.385 150.680 183.080 1.00 54.77  ? 213 VAL B O   1 
ATOM   3676 C  CB  . VAL B 2 231 ? 145.466 152.227 180.827 1.00 50.56  ? 213 VAL B CB  1 
ATOM   3677 C  CG1 . VAL B 2 231 ? 146.885 152.244 180.322 1.00 50.19  ? 213 VAL B CG1 1 
ATOM   3678 C  CG2 . VAL B 2 231 ? 144.517 151.897 179.705 1.00 51.66  ? 213 VAL B CG2 1 
ATOM   3679 N  N   . ARG B 2 232 ? 146.219 152.419 183.896 1.00 60.68  ? 214 ARG B N   1 
ATOM   3680 C  CA  . ARG B 2 232 ? 147.289 152.790 184.817 1.00 60.99  ? 214 ARG B CA  1 
ATOM   3681 C  C   . ARG B 2 232 ? 147.496 151.738 185.900 1.00 64.72  ? 214 ARG B C   1 
ATOM   3682 O  O   . ARG B 2 232 ? 148.630 151.501 186.327 1.00 68.21  ? 214 ARG B O   1 
ATOM   3683 C  CB  . ARG B 2 232 ? 146.994 154.152 185.440 1.00 63.73  ? 214 ARG B CB  1 
ATOM   3684 C  CG  . ARG B 2 232 ? 146.838 155.274 184.425 1.00 63.48  ? 214 ARG B CG  1 
ATOM   3685 C  CD  . ARG B 2 232 ? 148.102 156.116 184.318 1.00 65.61  ? 214 ARG B CD  1 
ATOM   3686 N  NE  . ARG B 2 232 ? 149.215 155.369 183.741 1.00 70.80  ? 214 ARG B NE  1 
ATOM   3687 C  CZ  . ARG B 2 232 ? 149.397 155.178 182.441 1.00 69.42  ? 214 ARG B CZ  1 
ATOM   3688 N  NH1 . ARG B 2 232 ? 148.555 155.667 181.545 1.00 65.85  ? 214 ARG B NH1 1 
ATOM   3689 N  NH2 . ARG B 2 232 ? 150.450 154.477 182.029 1.00 64.49  ? 214 ARG B NH2 1 
ATOM   3690 N  N   . GLU B 2 233 ? 146.421 151.096 186.358 1.00 67.50  ? 215 GLU B N   1 
ATOM   3691 C  CA  . GLU B 2 233 ? 146.528 150.107 187.422 1.00 67.00  ? 215 GLU B CA  1 
ATOM   3692 C  C   . GLU B 2 233 ? 146.514 148.667 186.928 1.00 66.66  ? 215 GLU B C   1 
ATOM   3693 O  O   . GLU B 2 233 ? 146.884 147.770 187.690 1.00 67.19  ? 215 GLU B O   1 
ATOM   3694 C  CB  . GLU B 2 233 ? 145.400 150.297 188.439 1.00 68.52  ? 215 GLU B CB  1 
ATOM   3695 C  CG  . GLU B 2 233 ? 145.747 151.253 189.564 1.00 71.38  ? 215 GLU B CG  1 
ATOM   3696 C  CD  . GLU B 2 233 ? 147.053 150.894 190.249 1.00 74.84  ? 215 GLU B CD  1 
ATOM   3697 O  OE1 . GLU B 2 233 ? 147.226 149.716 190.627 1.00 71.55  ? 215 GLU B OE1 1 
ATOM   3698 O  OE2 . GLU B 2 233 ? 147.909 151.790 190.409 1.00 75.58  ? 215 GLU B OE2 1 
ATOM   3699 N  N   . GLY B 2 234 ? 146.104 148.425 185.689 1.00 63.49  ? 216 GLY B N   1 
ATOM   3700 C  CA  . GLY B 2 234 ? 146.175 147.094 185.106 1.00 60.79  ? 216 GLY B CA  1 
ATOM   3701 C  C   . GLY B 2 234 ? 145.268 146.049 185.717 1.00 62.02  ? 216 GLY B C   1 
ATOM   3702 O  O   . GLY B 2 234 ? 145.681 144.895 185.877 1.00 64.56  ? 216 GLY B O   1 
ATOM   3703 N  N   . MET B 2 235 ? 144.038 146.416 186.048 1.00 55.08  ? 217 MET B N   1 
ATOM   3704 C  CA  . MET B 2 235 ? 143.058 145.501 186.615 1.00 55.55  ? 217 MET B CA  1 
ATOM   3705 C  C   . MET B 2 235 ? 141.800 145.505 185.754 1.00 54.95  ? 217 MET B C   1 
ATOM   3706 O  O   . MET B 2 235 ? 141.712 146.212 184.751 1.00 56.86  ? 217 MET B O   1 
ATOM   3707 C  CB  . MET B 2 235 ? 142.733 145.882 188.062 1.00 55.11  ? 217 MET B CB  1 
ATOM   3708 C  CG  . MET B 2 235 ? 142.110 147.252 188.212 1.00 57.17  ? 217 MET B CG  1 
ATOM   3709 S  SD  . MET B 2 235 ? 142.781 148.170 189.606 1.00 73.02  ? 217 MET B SD  1 
ATOM   3710 C  CE  . MET B 2 235 ? 141.792 149.662 189.538 1.00 56.89  ? 217 MET B CE  1 
ATOM   3711 N  N   . CYS B 2 236 ? 140.821 144.698 186.150 1.00 45.35  ? 218 CYS B N   1 
ATOM   3712 C  CA  . CYS B 2 236 ? 139.521 144.646 185.493 1.00 43.16  ? 218 CYS B CA  1 
ATOM   3713 C  C   . CYS B 2 236 ? 138.479 145.191 186.456 1.00 43.35  ? 218 CYS B C   1 
ATOM   3714 O  O   . CYS B 2 236 ? 138.350 144.694 187.577 1.00 44.84  ? 218 CYS B O   1 
ATOM   3715 C  CB  . CYS B 2 236 ? 139.171 143.219 185.072 1.00 42.15  ? 218 CYS B CB  1 
ATOM   3716 S  SG  . CYS B 2 236 ? 137.699 143.063 184.048 1.00 30.00  ? 218 CYS B SG  1 
ATOM   3717 N  N   . ARG B 2 237 ? 137.733 146.200 186.017 1.00 45.56  ? 219 ARG B N   1 
ATOM   3718 C  CA  . ARG B 2 237 ? 136.756 146.865 186.870 1.00 46.13  ? 219 ARG B CA  1 
ATOM   3719 C  C   . ARG B 2 237 ? 135.335 146.354 186.679 1.00 43.99  ? 219 ARG B C   1 
ATOM   3720 O  O   . ARG B 2 237 ? 134.606 146.200 187.661 1.00 44.42  ? 219 ARG B O   1 
ATOM   3721 C  CB  . ARG B 2 237 ? 136.793 148.374 186.626 1.00 42.41  ? 219 ARG B CB  1 
ATOM   3722 C  CG  . ARG B 2 237 ? 138.091 149.020 187.053 1.00 44.65  ? 219 ARG B CG  1 
ATOM   3723 C  CD  . ARG B 2 237 ? 138.041 150.518 186.856 1.00 46.30  ? 219 ARG B CD  1 
ATOM   3724 N  NE  . ARG B 2 237 ? 139.295 151.150 187.241 1.00 49.69  ? 219 ARG B NE  1 
ATOM   3725 C  CZ  . ARG B 2 237 ? 139.617 151.476 188.484 1.00 49.76  ? 219 ARG B CZ  1 
ATOM   3726 N  NH1 . ARG B 2 237 ? 138.795 151.246 189.494 1.00 46.08  ? 219 ARG B NH1 1 
ATOM   3727 N  NH2 . ARG B 2 237 ? 140.794 152.050 188.721 1.00 49.32  ? 219 ARG B NH2 1 
ATOM   3728 N  N   . GLN B 2 238 ? 134.912 146.098 185.443 1.00 33.07  ? 220 GLN B N   1 
ATOM   3729 C  CA  . GLN B 2 238 ? 133.562 145.630 185.181 1.00 33.21  ? 220 GLN B CA  1 
ATOM   3730 C  C   . GLN B 2 238 ? 133.577 144.591 184.073 1.00 36.96  ? 220 GLN B C   1 
ATOM   3731 O  O   . GLN B 2 238 ? 134.428 144.623 183.180 1.00 39.08  ? 220 GLN B O   1 
ATOM   3732 C  CB  . GLN B 2 238 ? 132.631 146.783 184.794 1.00 35.60  ? 220 GLN B CB  1 
ATOM   3733 C  CG  . GLN B 2 238 ? 132.427 147.813 185.884 1.00 38.85  ? 220 GLN B CG  1 
ATOM   3734 C  CD  . GLN B 2 238 ? 131.750 149.064 185.384 1.00 37.60  ? 220 GLN B CD  1 
ATOM   3735 O  OE1 . GLN B 2 238 ? 130.900 149.010 184.506 1.00 34.82  ? 220 GLN B OE1 1 
ATOM   3736 N  NE2 . GLN B 2 238 ? 132.125 150.203 185.943 1.00 37.39  ? 220 GLN B NE2 1 
ATOM   3737 N  N   . THR B 2 239 ? 132.615 143.671 184.141 1.00 35.99  ? 221 THR B N   1 
ATOM   3738 C  CA  . THR B 2 239 ? 132.395 142.650 183.126 1.00 30.16  ? 221 THR B CA  1 
ATOM   3739 C  C   . THR B 2 239 ? 130.943 142.712 182.679 1.00 29.75  ? 221 THR B C   1 
ATOM   3740 O  O   . THR B 2 239 ? 130.038 142.800 183.513 1.00 30.85  ? 221 THR B O   1 
ATOM   3741 C  CB  . THR B 2 239 ? 132.715 141.249 183.653 1.00 29.38  ? 221 THR B CB  1 
ATOM   3742 O  OG1 . THR B 2 239 ? 133.945 141.276 184.385 1.00 32.37  ? 221 THR B OG1 1 
ATOM   3743 C  CG2 . THR B 2 239 ? 132.839 140.265 182.511 1.00 25.63  ? 221 THR B CG2 1 
ATOM   3744 N  N   . PHE B 2 240 ? 130.725 142.660 181.369 1.00 21.90  ? 222 PHE B N   1 
ATOM   3745 C  CA  . PHE B 2 240 ? 129.398 142.767 180.775 1.00 18.27  ? 222 PHE B CA  1 
ATOM   3746 C  C   . PHE B 2 240 ? 129.136 141.520 179.947 1.00 22.58  ? 222 PHE B C   1 
ATOM   3747 O  O   . PHE B 2 240 ? 129.921 141.192 179.052 1.00 30.06  ? 222 PHE B O   1 
ATOM   3748 C  CB  . PHE B 2 240 ? 129.285 144.024 179.910 1.00 20.80  ? 222 PHE B CB  1 
ATOM   3749 C  CG  . PHE B 2 240 ? 129.738 145.282 180.599 1.00 27.79  ? 222 PHE B CG  1 
ATOM   3750 C  CD1 . PHE B 2 240 ? 131.064 145.668 180.565 1.00 22.22  ? 222 PHE B CD1 1 
ATOM   3751 C  CD2 . PHE B 2 240 ? 128.835 146.081 181.272 1.00 28.57  ? 222 PHE B CD2 1 
ATOM   3752 C  CE1 . PHE B 2 240 ? 131.475 146.811 181.193 1.00 21.22  ? 222 PHE B CE1 1 
ATOM   3753 C  CE2 . PHE B 2 240 ? 129.247 147.224 181.900 1.00 20.70  ? 222 PHE B CE2 1 
ATOM   3754 C  CZ  . PHE B 2 240 ? 130.566 147.589 181.859 1.00 22.44  ? 222 PHE B CZ  1 
ATOM   3755 N  N   . THR B 2 241 ? 128.035 140.832 180.243 1.00 25.17  ? 223 THR B N   1 
ATOM   3756 C  CA  . THR B 2 241 ? 127.667 139.583 179.576 1.00 26.43  ? 223 THR B CA  1 
ATOM   3757 C  C   . THR B 2 241 ? 126.206 139.670 179.151 1.00 29.84  ? 223 THR B C   1 
ATOM   3758 O  O   . THR B 2 241 ? 125.308 139.407 179.953 1.00 36.34  ? 223 THR B O   1 
ATOM   3759 C  CB  . THR B 2 241 ? 127.880 138.376 180.486 1.00 26.09  ? 223 THR B CB  1 
ATOM   3760 O  OG1 . THR B 2 241 ? 127.167 138.568 181.713 1.00 19.88  ? 223 THR B OG1 1 
ATOM   3761 C  CG2 . THR B 2 241 ? 129.349 138.170 180.788 1.00 24.81  ? 223 THR B CG2 1 
ATOM   3762 N  N   . GLY B 2 242 ? 125.962 140.040 177.901 1.00 24.88  ? 224 GLY B N   1 
ATOM   3763 C  CA  . GLY B 2 242 ? 124.622 139.961 177.366 1.00 17.95  ? 224 GLY B CA  1 
ATOM   3764 C  C   . GLY B 2 242 ? 124.535 139.148 176.093 1.00 20.84  ? 224 GLY B C   1 
ATOM   3765 O  O   . GLY B 2 242 ? 123.497 138.550 175.805 1.00 28.89  ? 224 GLY B O   1 
ATOM   3766 N  N   . HIS B 2 243 ? 125.625 139.096 175.336 1.00 16.79  ? 225 HIS B N   1 
ATOM   3767 C  CA  . HIS B 2 243 ? 125.612 138.427 174.048 1.00 9.74   ? 225 HIS B CA  1 
ATOM   3768 C  C   . HIS B 2 243 ? 125.574 136.914 174.236 1.00 23.41  ? 225 HIS B C   1 
ATOM   3769 O  O   . HIS B 2 243 ? 125.800 136.389 175.329 1.00 33.72  ? 225 HIS B O   1 
ATOM   3770 C  CB  . HIS B 2 243 ? 126.832 138.830 173.224 1.00 17.55  ? 225 HIS B CB  1 
ATOM   3771 C  CG  . HIS B 2 243 ? 126.698 140.162 172.551 1.00 27.16  ? 225 HIS B CG  1 
ATOM   3772 N  ND1 . HIS B 2 243 ? 125.866 140.372 171.475 1.00 25.62  ? 225 HIS B ND1 1 
ATOM   3773 C  CD2 . HIS B 2 243 ? 127.298 141.348 172.798 1.00 18.19  ? 225 HIS B CD2 1 
ATOM   3774 C  CE1 . HIS B 2 243 ? 125.957 141.630 171.091 1.00 13.13  ? 225 HIS B CE1 1 
ATOM   3775 N  NE2 . HIS B 2 243 ? 126.818 142.244 171.877 1.00 13.22  ? 225 HIS B NE2 1 
ATOM   3776 N  N   . GLU B 2 244 ? 125.288 136.205 173.143 1.00 24.26  ? 226 GLU B N   1 
ATOM   3777 C  CA  . GLU B 2 244 ? 125.190 134.752 173.162 1.00 25.01  ? 226 GLU B CA  1 
ATOM   3778 C  C   . GLU B 2 244 ? 126.326 134.043 172.441 1.00 24.17  ? 226 GLU B C   1 
ATOM   3779 O  O   . GLU B 2 244 ? 126.452 132.825 172.583 1.00 31.31  ? 226 GLU B O   1 
ATOM   3780 C  CB  . GLU B 2 244 ? 123.857 134.300 172.550 1.00 17.36  ? 226 GLU B CB  1 
ATOM   3781 C  CG  . GLU B 2 244 ? 122.660 134.583 173.428 1.00 29.10  ? 226 GLU B CG  1 
ATOM   3782 C  CD  . GLU B 2 244 ? 121.364 134.665 172.651 1.00 35.49  ? 226 GLU B CD  1 
ATOM   3783 O  OE1 . GLU B 2 244 ? 121.341 134.242 171.480 1.00 29.92  ? 226 GLU B OE1 1 
ATOM   3784 O  OE2 . GLU B 2 244 ? 120.363 135.150 173.216 1.00 33.29  ? 226 GLU B OE2 1 
ATOM   3785 N  N   . SER B 2 245 ? 127.151 134.753 171.680 1.00 14.72  ? 227 SER B N   1 
ATOM   3786 C  CA  . SER B 2 245 ? 128.232 134.130 170.932 1.00 6.04   ? 227 SER B CA  1 
ATOM   3787 C  C   . SER B 2 245 ? 129.419 135.085 170.909 1.00 19.76  ? 227 SER B C   1 
ATOM   3788 O  O   . SER B 2 245 ? 129.421 136.111 171.592 1.00 34.41  ? 227 SER B O   1 
ATOM   3789 C  CB  . SER B 2 245 ? 127.759 133.746 169.529 1.00 12.56  ? 227 SER B CB  1 
ATOM   3790 O  OG  . SER B 2 245 ? 128.613 132.781 168.960 1.00 18.64  ? 227 SER B OG  1 
ATOM   3791 N  N   . ASP B 2 246 ? 130.433 134.743 170.115 1.00 15.65  ? 228 ASP B N   1 
ATOM   3792 C  CA  . ASP B 2 246 ? 131.679 135.500 170.094 1.00 10.14  ? 228 ASP B CA  1 
ATOM   3793 C  C   . ASP B 2 246 ? 131.447 136.943 169.678 1.00 13.06  ? 228 ASP B C   1 
ATOM   3794 O  O   . ASP B 2 246 ? 130.697 137.221 168.743 1.00 18.30  ? 228 ASP B O   1 
ATOM   3795 C  CB  . ASP B 2 246 ? 132.670 134.845 169.138 1.00 4.95   ? 228 ASP B CB  1 
ATOM   3796 C  CG  . ASP B 2 246 ? 132.599 133.340 169.175 1.00 25.90  ? 228 ASP B CG  1 
ATOM   3797 O  OD1 . ASP B 2 246 ? 132.704 132.775 170.279 1.00 28.92  ? 228 ASP B OD1 1 
ATOM   3798 O  OD2 . ASP B 2 246 ? 132.427 132.716 168.108 1.00 26.71  ? 228 ASP B OD2 1 
ATOM   3799 N  N   . ILE B 2 247 ? 132.111 137.862 170.374 1.00 11.32  ? 229 ILE B N   1 
ATOM   3800 C  CA  . ILE B 2 247 ? 132.032 139.289 170.082 1.00 7.45   ? 229 ILE B CA  1 
ATOM   3801 C  C   . ILE B 2 247 ? 133.155 139.642 169.120 1.00 12.94  ? 229 ILE B C   1 
ATOM   3802 O  O   . ILE B 2 247 ? 134.326 139.371 169.398 1.00 14.47  ? 229 ILE B O   1 
ATOM   3803 C  CB  . ILE B 2 247 ? 132.129 140.122 171.366 1.00 6.14   ? 229 ILE B CB  1 
ATOM   3804 C  CG1 . ILE B 2 247 ? 130.868 139.956 172.203 1.00 6.49   ? 229 ILE B CG1 1 
ATOM   3805 C  CG2 . ILE B 2 247 ? 132.362 141.578 171.040 1.00 12.66  ? 229 ILE B CG2 1 
ATOM   3806 C  CD1 . ILE B 2 247 ? 130.950 140.623 173.528 1.00 9.92   ? 229 ILE B CD1 1 
ATOM   3807 N  N   . ASN B 2 248 ? 132.802 140.245 167.985 1.00 11.29  ? 230 ASN B N   1 
ATOM   3808 C  CA  . ASN B 2 248 ? 133.759 140.529 166.925 1.00 8.56   ? 230 ASN B CA  1 
ATOM   3809 C  C   . ASN B 2 248 ? 134.273 141.958 166.934 1.00 17.29  ? 230 ASN B C   1 
ATOM   3810 O  O   . ASN B 2 248 ? 135.421 142.188 166.551 1.00 13.16  ? 230 ASN B O   1 
ATOM   3811 C  CB  . ASN B 2 248 ? 133.127 140.248 165.562 1.00 6.99   ? 230 ASN B CB  1 
ATOM   3812 C  CG  . ASN B 2 248 ? 132.779 138.804 165.374 1.00 13.81  ? 230 ASN B CG  1 
ATOM   3813 O  OD1 . ASN B 2 248 ? 133.538 137.919 165.750 1.00 25.40  ? 230 ASN B OD1 1 
ATOM   3814 N  ND2 . ASN B 2 248 ? 131.626 138.550 164.781 1.00 10.02  ? 230 ASN B ND2 1 
ATOM   3815 N  N   . ALA B 2 249 ? 133.454 142.919 167.352 1.00 15.87  ? 231 ALA B N   1 
ATOM   3816 C  CA  . ALA B 2 249 ? 133.805 144.326 167.300 1.00 9.35   ? 231 ALA B CA  1 
ATOM   3817 C  C   . ALA B 2 249 ? 133.314 145.022 168.557 1.00 9.89   ? 231 ALA B C   1 
ATOM   3818 O  O   . ALA B 2 249 ? 132.408 144.545 169.240 1.00 15.55  ? 231 ALA B O   1 
ATOM   3819 C  CB  . ALA B 2 249 ? 133.213 144.999 166.069 1.00 1.39   ? 231 ALA B CB  1 
ATOM   3820 N  N   . ILE B 2 250 ? 133.928 146.163 168.855 1.00 11.98  ? 232 ILE B N   1 
ATOM   3821 C  CA  . ILE B 2 250 ? 133.570 146.966 170.019 1.00 8.10   ? 232 ILE B CA  1 
ATOM   3822 C  C   . ILE B 2 250 ? 133.969 148.411 169.743 1.00 9.76   ? 232 ILE B C   1 
ATOM   3823 O  O   . ILE B 2 250 ? 134.979 148.676 169.087 1.00 16.44  ? 232 ILE B O   1 
ATOM   3824 C  CB  . ILE B 2 250 ? 134.217 146.401 171.307 1.00 10.94  ? 232 ILE B CB  1 
ATOM   3825 C  CG1 . ILE B 2 250 ? 133.495 146.906 172.548 1.00 9.05   ? 232 ILE B CG1 1 
ATOM   3826 C  CG2 . ILE B 2 250 ? 135.678 146.735 171.394 1.00 12.40  ? 232 ILE B CG2 1 
ATOM   3827 C  CD1 . ILE B 2 250 ? 133.749 146.079 173.744 1.00 4.86   ? 232 ILE B CD1 1 
ATOM   3828 N  N   . CYS B 2 251 ? 133.148 149.344 170.220 1.00 11.95  ? 233 CYS B N   1 
ATOM   3829 C  CA  . CYS B 2 251 ? 133.360 150.769 170.011 1.00 13.09  ? 233 CYS B CA  1 
ATOM   3830 C  C   . CYS B 2 251 ? 132.907 151.517 171.254 1.00 13.69  ? 233 CYS B C   1 
ATOM   3831 O  O   . CYS B 2 251 ? 132.083 151.027 172.021 1.00 24.11  ? 233 CYS B O   1 
ATOM   3832 C  CB  . CYS B 2 251 ? 132.600 151.278 168.778 1.00 8.09   ? 233 CYS B CB  1 
ATOM   3833 S  SG  . CYS B 2 251 ? 133.380 152.657 167.921 1.00 32.29  ? 233 CYS B SG  1 
ATOM   3834 N  N   . PHE B 2 252 ? 133.445 152.717 171.440 1.00 13.71  ? 234 PHE B N   1 
ATOM   3835 C  CA  . PHE B 2 252 ? 133.148 153.556 172.592 1.00 15.15  ? 234 PHE B CA  1 
ATOM   3836 C  C   . PHE B 2 252 ? 132.238 154.708 172.185 1.00 20.01  ? 234 PHE B C   1 
ATOM   3837 O  O   . PHE B 2 252 ? 132.426 155.309 171.125 1.00 23.84  ? 234 PHE B O   1 
ATOM   3838 C  CB  . PHE B 2 252 ? 134.435 154.113 173.200 1.00 17.44  ? 234 PHE B CB  1 
ATOM   3839 C  CG  . PHE B 2 252 ? 134.679 153.701 174.622 1.00 16.02  ? 234 PHE B CG  1 
ATOM   3840 C  CD1 . PHE B 2 252 ? 133.769 153.992 175.608 1.00 19.67  ? 234 PHE B CD1 1 
ATOM   3841 C  CD2 . PHE B 2 252 ? 135.837 153.040 174.973 1.00 10.14  ? 234 PHE B CD2 1 
ATOM   3842 C  CE1 . PHE B 2 252 ? 134.004 153.621 176.910 1.00 19.58  ? 234 PHE B CE1 1 
ATOM   3843 C  CE2 . PHE B 2 252 ? 136.070 152.674 176.268 1.00 8.50   ? 234 PHE B CE2 1 
ATOM   3844 C  CZ  . PHE B 2 252 ? 135.155 152.965 177.237 1.00 10.63  ? 234 PHE B CZ  1 
ATOM   3845 N  N   . PHE B 2 253 ? 131.261 155.018 173.036 1.00 17.24  ? 235 PHE B N   1 
ATOM   3846 C  CA  . PHE B 2 253 ? 130.378 156.154 172.812 1.00 16.41  ? 235 PHE B CA  1 
ATOM   3847 C  C   . PHE B 2 253 ? 131.170 157.463 172.874 1.00 29.64  ? 235 PHE B C   1 
ATOM   3848 O  O   . PHE B 2 253 ? 132.209 157.534 173.534 1.00 29.82  ? 235 PHE B O   1 
ATOM   3849 C  CB  . PHE B 2 253 ? 129.267 156.166 173.859 1.00 13.17  ? 235 PHE B CB  1 
ATOM   3850 C  CG  . PHE B 2 253 ? 128.048 156.948 173.459 1.00 21.70  ? 235 PHE B CG  1 
ATOM   3851 C  CD1 . PHE B 2 253 ? 127.148 156.437 172.550 1.00 25.15  ? 235 PHE B CD1 1 
ATOM   3852 C  CD2 . PHE B 2 253 ? 127.794 158.189 174.009 1.00 21.94  ? 235 PHE B CD2 1 
ATOM   3853 C  CE1 . PHE B 2 253 ? 126.032 157.154 172.191 1.00 21.94  ? 235 PHE B CE1 1 
ATOM   3854 C  CE2 . PHE B 2 253 ? 126.681 158.909 173.651 1.00 22.23  ? 235 PHE B CE2 1 
ATOM   3855 C  CZ  . PHE B 2 253 ? 125.800 158.391 172.742 1.00 23.05  ? 235 PHE B CZ  1 
ATOM   3856 N  N   . PRO B 2 254 ? 130.704 158.512 172.183 1.00 27.49  ? 236 PRO B N   1 
ATOM   3857 C  CA  . PRO B 2 254 ? 131.453 159.779 172.164 1.00 20.18  ? 236 PRO B CA  1 
ATOM   3858 C  C   . PRO B 2 254 ? 131.814 160.367 173.521 1.00 22.06  ? 236 PRO B C   1 
ATOM   3859 O  O   . PRO B 2 254 ? 132.896 160.948 173.641 1.00 26.46  ? 236 PRO B O   1 
ATOM   3860 C  CB  . PRO B 2 254 ? 130.507 160.696 171.387 1.00 19.04  ? 236 PRO B CB  1 
ATOM   3861 C  CG  . PRO B 2 254 ? 129.886 159.800 170.412 1.00 13.20  ? 236 PRO B CG  1 
ATOM   3862 C  CD  . PRO B 2 254 ? 129.731 158.462 171.076 1.00 19.32  ? 236 PRO B CD  1 
ATOM   3863 N  N   . ASN B 2 255 ? 130.964 160.264 174.537 1.00 18.41  ? 237 ASN B N   1 
ATOM   3864 C  CA  . ASN B 2 255 ? 131.328 160.803 175.842 1.00 21.38  ? 237 ASN B CA  1 
ATOM   3865 C  C   . ASN B 2 255 ? 132.001 159.778 176.749 1.00 31.35  ? 237 ASN B C   1 
ATOM   3866 O  O   . ASN B 2 255 ? 132.389 160.126 177.867 1.00 32.48  ? 237 ASN B O   1 
ATOM   3867 C  CB  . ASN B 2 255 ? 130.103 161.406 176.542 1.00 19.95  ? 237 ASN B CB  1 
ATOM   3868 C  CG  . ASN B 2 255 ? 129.041 160.385 176.859 1.00 30.02  ? 237 ASN B CG  1 
ATOM   3869 O  OD1 . ASN B 2 255 ? 129.096 159.254 176.401 1.00 35.01  ? 237 ASN B OD1 1 
ATOM   3870 N  ND2 . ASN B 2 255 ? 128.057 160.786 177.650 1.00 33.44  ? 237 ASN B ND2 1 
ATOM   3871 N  N   . GLY B 2 256 ? 132.167 158.539 176.293 1.00 25.59  ? 238 GLY B N   1 
ATOM   3872 C  CA  . GLY B 2 256 ? 132.907 157.553 177.052 1.00 20.02  ? 238 GLY B CA  1 
ATOM   3873 C  C   . GLY B 2 256 ? 132.179 156.945 178.225 1.00 24.05  ? 238 GLY B C   1 
ATOM   3874 O  O   . GLY B 2 256 ? 132.828 156.400 179.121 1.00 28.23  ? 238 GLY B O   1 
ATOM   3875 N  N   . ASN B 2 257 ? 130.849 157.020 178.256 1.00 22.31  ? 239 ASN B N   1 
ATOM   3876 C  CA  . ASN B 2 257 ? 130.055 156.456 179.341 1.00 23.54  ? 239 ASN B CA  1 
ATOM   3877 C  C   . ASN B 2 257 ? 129.163 155.315 178.870 1.00 28.53  ? 239 ASN B C   1 
ATOM   3878 O  O   . ASN B 2 257 ? 128.212 154.951 179.565 1.00 27.46  ? 239 ASN B O   1 
ATOM   3879 C  CB  . ASN B 2 257 ? 129.216 157.547 180.003 1.00 26.97  ? 239 ASN B CB  1 
ATOM   3880 C  CG  . ASN B 2 257 ? 130.018 158.389 180.975 1.00 35.07  ? 239 ASN B CG  1 
ATOM   3881 O  OD1 . ASN B 2 257 ? 130.915 157.890 181.649 1.00 36.40  ? 239 ASN B OD1 1 
ATOM   3882 N  ND2 . ASN B 2 257 ? 129.697 159.673 181.050 1.00 28.24  ? 239 ASN B ND2 1 
ATOM   3883 N  N   . ALA B 2 258 ? 129.448 154.755 177.700 1.00 29.61  ? 240 ALA B N   1 
ATOM   3884 C  CA  . ALA B 2 258 ? 128.707 153.633 177.140 1.00 16.69  ? 240 ALA B CA  1 
ATOM   3885 C  C   . ALA B 2 258 ? 129.547 153.057 176.012 1.00 21.44  ? 240 ALA B C   1 
ATOM   3886 O  O   . ALA B 2 258 ? 130.550 153.644 175.605 1.00 22.79  ? 240 ALA B O   1 
ATOM   3887 C  CB  . ALA B 2 258 ? 127.326 154.054 176.644 1.00 11.52  ? 240 ALA B CB  1 
ATOM   3888 N  N   . PHE B 2 259 ? 129.140 151.892 175.522 1.00 15.81  ? 241 PHE B N   1 
ATOM   3889 C  CA  . PHE B 2 259 ? 129.850 151.277 174.406 1.00 6.33   ? 241 PHE B CA  1 
ATOM   3890 C  C   . PHE B 2 259 ? 128.925 150.290 173.708 1.00 9.97   ? 241 PHE B C   1 
ATOM   3891 O  O   . PHE B 2 259 ? 127.867 149.934 174.222 1.00 16.52  ? 241 PHE B O   1 
ATOM   3892 C  CB  . PHE B 2 259 ? 131.170 150.629 174.862 1.00 7.40   ? 241 PHE B CB  1 
ATOM   3893 C  CG  . PHE B 2 259 ? 131.011 149.454 175.774 1.00 20.29  ? 241 PHE B CG  1 
ATOM   3894 C  CD1 . PHE B 2 259 ? 130.943 149.628 177.141 1.00 18.11  ? 241 PHE B CD1 1 
ATOM   3895 C  CD2 . PHE B 2 259 ? 130.971 148.169 175.269 1.00 22.99  ? 241 PHE B CD2 1 
ATOM   3896 C  CE1 . PHE B 2 259 ? 130.810 148.551 177.973 1.00 14.61  ? 241 PHE B CE1 1 
ATOM   3897 C  CE2 . PHE B 2 259 ? 130.839 147.091 176.106 1.00 15.19  ? 241 PHE B CE2 1 
ATOM   3898 C  CZ  . PHE B 2 259 ? 130.762 147.282 177.455 1.00 13.89  ? 241 PHE B CZ  1 
ATOM   3899 N  N   . ALA B 2 260 ? 129.323 149.879 172.505 1.00 11.18  ? 242 ALA B N   1 
ATOM   3900 C  CA  . ALA B 2 260 ? 128.506 149.022 171.658 1.00 8.80   ? 242 ALA B CA  1 
ATOM   3901 C  C   . ALA B 2 260 ? 129.295 147.805 171.206 1.00 12.65  ? 242 ALA B C   1 
ATOM   3902 O  O   . ALA B 2 260 ? 130.484 147.903 170.902 1.00 14.85  ? 242 ALA B O   1 
ATOM   3903 C  CB  . ALA B 2 260 ? 127.995 149.772 170.436 1.00 12.41  ? 242 ALA B CB  1 
ATOM   3904 N  N   . THR B 2 261 ? 128.617 146.662 171.150 1.00 15.33  ? 243 THR B N   1 
ATOM   3905 C  CA  . THR B 2 261 ? 129.232 145.386 170.811 1.00 10.20  ? 243 THR B CA  1 
ATOM   3906 C  C   . THR B 2 261 ? 128.440 144.704 169.709 1.00 8.22   ? 243 THR B C   1 
ATOM   3907 O  O   . THR B 2 261 ? 127.208 144.746 169.708 1.00 25.90  ? 243 THR B O   1 
ATOM   3908 C  CB  . THR B 2 261 ? 129.299 144.454 172.034 1.00 22.84  ? 243 THR B CB  1 
ATOM   3909 O  OG1 . THR B 2 261 ? 127.981 144.221 172.537 1.00 20.27  ? 243 THR B OG1 1 
ATOM   3910 C  CG2 . THR B 2 261 ? 130.155 145.042 173.139 1.00 17.50  ? 243 THR B CG2 1 
ATOM   3911 N  N   . GLY B 2 262 ? 129.144 144.071 168.787 1.00 5.61   ? 244 GLY B N   1 
ATOM   3912 C  CA  . GLY B 2 262 ? 128.507 143.257 167.763 1.00 14.97  ? 244 GLY B CA  1 
ATOM   3913 C  C   . GLY B 2 262 ? 129.104 141.869 167.736 1.00 15.16  ? 244 GLY B C   1 
ATOM   3914 O  O   . GLY B 2 262 ? 130.312 141.705 167.857 1.00 21.21  ? 244 GLY B O   1 
ATOM   3915 N  N   . SER B 2 263 ? 128.243 140.866 167.574 1.00 13.46  ? 245 SER B N   1 
ATOM   3916 C  CA  . SER B 2 263 ? 128.661 139.486 167.789 1.00 11.50  ? 245 SER B CA  1 
ATOM   3917 C  C   . SER B 2 263 ? 128.098 138.590 166.693 1.00 13.43  ? 245 SER B C   1 
ATOM   3918 O  O   . SER B 2 263 ? 127.526 139.059 165.707 1.00 17.37  ? 245 SER B O   1 
ATOM   3919 C  CB  . SER B 2 263 ? 128.230 139.006 169.178 1.00 14.62  ? 245 SER B CB  1 
ATOM   3920 O  OG  . SER B 2 263 ? 126.826 139.046 169.305 1.00 29.32  ? 245 SER B OG  1 
ATOM   3921 N  N   . ASP B 2 264 ? 128.266 137.279 166.884 1.00 22.80  ? 246 ASP B N   1 
ATOM   3922 C  CA  . ASP B 2 264 ? 127.873 136.253 165.922 1.00 19.71  ? 246 ASP B CA  1 
ATOM   3923 C  C   . ASP B 2 264 ? 126.408 135.852 166.007 1.00 14.43  ? 246 ASP B C   1 
ATOM   3924 O  O   . ASP B 2 264 ? 125.928 135.167 165.103 1.00 23.39  ? 246 ASP B O   1 
ATOM   3925 C  CB  . ASP B 2 264 ? 128.725 135.001 166.110 1.00 14.41  ? 246 ASP B CB  1 
ATOM   3926 C  CG  . ASP B 2 264 ? 129.953 134.998 165.243 1.00 27.44  ? 246 ASP B CG  1 
ATOM   3927 O  OD1 . ASP B 2 264 ? 129.959 135.702 164.217 1.00 22.80  ? 246 ASP B OD1 1 
ATOM   3928 O  OD2 . ASP B 2 264 ? 130.915 134.285 165.583 1.00 33.87  ? 246 ASP B OD2 1 
ATOM   3929 N  N   . ASP B 2 265 ? 125.691 136.229 167.059 1.00 6.75   ? 247 ASP B N   1 
ATOM   3930 C  CA  . ASP B 2 265 ? 124.269 135.930 167.133 1.00 5.40   ? 247 ASP B CA  1 
ATOM   3931 C  C   . ASP B 2 265 ? 123.423 136.889 166.309 1.00 21.03  ? 247 ASP B C   1 
ATOM   3932 O  O   . ASP B 2 265 ? 122.195 136.873 166.449 1.00 23.53  ? 247 ASP B O   1 
ATOM   3933 C  CB  . ASP B 2 265 ? 123.790 135.940 168.583 1.00 14.08  ? 247 ASP B CB  1 
ATOM   3934 C  CG  . ASP B 2 265 ? 124.418 137.038 169.389 1.00 20.70  ? 247 ASP B CG  1 
ATOM   3935 O  OD1 . ASP B 2 265 ? 125.595 137.334 169.150 1.00 23.45  ? 247 ASP B OD1 1 
ATOM   3936 O  OD2 . ASP B 2 265 ? 123.740 137.605 170.264 1.00 22.96  ? 247 ASP B OD2 1 
ATOM   3937 N  N   . ALA B 2 266 ? 124.056 137.719 165.474 1.00 21.79  ? 248 ALA B N   1 
ATOM   3938 C  CA  . ALA B 2 266 ? 123.374 138.633 164.558 1.00 16.43  ? 248 ALA B CA  1 
ATOM   3939 C  C   . ALA B 2 266 ? 122.658 139.755 165.299 1.00 25.97  ? 248 ALA B C   1 
ATOM   3940 O  O   . ALA B 2 266 ? 121.583 140.190 164.891 1.00 36.02  ? 248 ALA B O   1 
ATOM   3941 C  CB  . ALA B 2 266 ? 122.398 137.890 163.646 1.00 15.93  ? 248 ALA B CB  1 
ATOM   3942 N  N   . THR B 2 267 ? 123.250 140.230 166.393 1.00 14.92  ? 249 THR B N   1 
ATOM   3943 C  CA  . THR B 2 267 ? 122.701 141.353 167.137 1.00 16.71  ? 249 THR B CA  1 
ATOM   3944 C  C   . THR B 2 267 ? 123.823 142.308 167.503 1.00 18.68  ? 249 THR B C   1 
ATOM   3945 O  O   . THR B 2 267 ? 124.995 141.934 167.535 1.00 22.21  ? 249 THR B O   1 
ATOM   3946 C  CB  . THR B 2 267 ? 121.982 140.921 168.421 1.00 14.53  ? 249 THR B CB  1 
ATOM   3947 O  OG1 . THR B 2 267 ? 122.921 140.305 169.306 1.00 23.35  ? 249 THR B OG1 1 
ATOM   3948 C  CG2 . THR B 2 267 ? 120.875 139.946 168.128 1.00 17.24  ? 249 THR B CG2 1 
ATOM   3949 N  N   . CYS B 2 268 ? 123.448 143.555 167.770 1.00 22.84  ? 250 CYS B N   1 
ATOM   3950 C  CA  . CYS B 2 268 ? 124.319 144.500 168.450 1.00 10.99  ? 250 CYS B CA  1 
ATOM   3951 C  C   . CYS B 2 268 ? 123.692 144.847 169.790 1.00 12.87  ? 250 CYS B C   1 
ATOM   3952 O  O   . CYS B 2 268 ? 122.486 144.705 169.981 1.00 20.16  ? 250 CYS B O   1 
ATOM   3953 C  CB  . CYS B 2 268 ? 124.544 145.778 167.630 1.00 14.76  ? 250 CYS B CB  1 
ATOM   3954 S  SG  . CYS B 2 268 ? 125.200 145.539 165.974 1.00 22.96  ? 250 CYS B SG  1 
ATOM   3955 N  N   . ARG B 2 269 ? 124.517 145.297 170.725 1.00 10.76  ? 251 ARG B N   1 
ATOM   3956 C  CA  . ARG B 2 269 ? 124.012 145.681 172.035 1.00 14.35  ? 251 ARG B CA  1 
ATOM   3957 C  C   . ARG B 2 269 ? 124.769 146.892 172.550 1.00 17.53  ? 251 ARG B C   1 
ATOM   3958 O  O   . ARG B 2 269 ? 125.944 147.090 172.240 1.00 21.03  ? 251 ARG B O   1 
ATOM   3959 C  CB  . ARG B 2 269 ? 124.115 144.535 173.044 1.00 19.93  ? 251 ARG B CB  1 
ATOM   3960 C  CG  . ARG B 2 269 ? 122.928 143.601 173.049 1.00 19.52  ? 251 ARG B CG  1 
ATOM   3961 C  CD  . ARG B 2 269 ? 123.296 142.252 173.619 1.00 15.58  ? 251 ARG B CD  1 
ATOM   3962 N  NE  . ARG B 2 269 ? 122.136 141.400 173.839 1.00 19.39  ? 251 ARG B NE  1 
ATOM   3963 C  CZ  . ARG B 2 269 ? 121.786 140.396 173.050 1.00 24.35  ? 251 ARG B CZ  1 
ATOM   3964 N  NH1 . ARG B 2 269 ? 122.467 140.109 171.956 1.00 19.91  ? 251 ARG B NH1 1 
ATOM   3965 N  NH2 . ARG B 2 269 ? 120.728 139.659 173.369 1.00 25.79  ? 251 ARG B NH2 1 
ATOM   3966 N  N   . LEU B 2 270 ? 124.080 147.696 173.353 1.00 11.12  ? 252 LEU B N   1 
ATOM   3967 C  CA  . LEU B 2 270 ? 124.646 148.900 173.944 1.00 10.76  ? 252 LEU B CA  1 
ATOM   3968 C  C   . LEU B 2 270 ? 124.674 148.750 175.457 1.00 19.67  ? 252 LEU B C   1 
ATOM   3969 O  O   . LEU B 2 270 ? 123.649 148.445 176.072 1.00 18.29  ? 252 LEU B O   1 
ATOM   3970 C  CB  . LEU B 2 270 ? 123.844 150.137 173.536 1.00 20.75  ? 252 LEU B CB  1 
ATOM   3971 C  CG  . LEU B 2 270 ? 124.100 151.471 174.236 1.00 26.36  ? 252 LEU B CG  1 
ATOM   3972 C  CD1 . LEU B 2 270 ? 124.994 152.341 173.399 1.00 16.68  ? 252 LEU B CD1 1 
ATOM   3973 C  CD2 . LEU B 2 270 ? 122.794 152.177 174.510 1.00 18.60  ? 252 LEU B CD2 1 
ATOM   3974 N  N   . PHE B 2 271 ? 125.848 148.971 176.047 1.00 19.99  ? 253 PHE B N   1 
ATOM   3975 C  CA  . PHE B 2 271 ? 126.079 148.820 177.474 1.00 19.75  ? 253 PHE B CA  1 
ATOM   3976 C  C   . PHE B 2 271 ? 126.447 150.162 178.085 1.00 22.86  ? 253 PHE B C   1 
ATOM   3977 O  O   . PHE B 2 271 ? 127.101 150.989 177.447 1.00 30.34  ? 253 PHE B O   1 
ATOM   3978 C  CB  . PHE B 2 271 ? 127.198 147.811 177.749 1.00 15.36  ? 253 PHE B CB  1 
ATOM   3979 C  CG  . PHE B 2 271 ? 126.878 146.416 177.311 1.00 19.65  ? 253 PHE B CG  1 
ATOM   3980 C  CD1 . PHE B 2 271 ? 127.170 145.994 176.034 1.00 25.73  ? 253 PHE B CD1 1 
ATOM   3981 C  CD2 . PHE B 2 271 ? 126.288 145.523 178.181 1.00 20.01  ? 253 PHE B CD2 1 
ATOM   3982 C  CE1 . PHE B 2 271 ? 126.872 144.712 175.635 1.00 19.58  ? 253 PHE B CE1 1 
ATOM   3983 C  CE2 . PHE B 2 271 ? 125.991 144.245 177.781 1.00 18.74  ? 253 PHE B CE2 1 
ATOM   3984 C  CZ  . PHE B 2 271 ? 126.281 143.840 176.509 1.00 12.29  ? 253 PHE B CZ  1 
ATOM   3985 N  N   . ASP B 2 272 ? 126.028 150.364 179.333 1.00 24.48  ? 254 ASP B N   1 
ATOM   3986 C  CA  . ASP B 2 272 ? 126.296 151.582 180.087 1.00 29.80  ? 254 ASP B CA  1 
ATOM   3987 C  C   . ASP B 2 272 ? 127.261 151.281 181.223 1.00 28.50  ? 254 ASP B C   1 
ATOM   3988 O  O   . ASP B 2 272 ? 127.015 150.377 182.023 1.00 36.41  ? 254 ASP B O   1 
ATOM   3989 C  CB  . ASP B 2 272 ? 125.001 152.175 180.647 1.00 33.64  ? 254 ASP B CB  1 
ATOM   3990 C  CG  . ASP B 2 272 ? 125.221 153.503 181.361 1.00 46.05  ? 254 ASP B CG  1 
ATOM   3991 O  OD1 . ASP B 2 272 ? 126.373 153.981 181.411 1.00 41.79  ? 254 ASP B OD1 1 
ATOM   3992 O  OD2 . ASP B 2 272 ? 124.240 154.076 181.873 1.00 46.65  ? 254 ASP B OD2 1 
ATOM   3993 N  N   . LEU B 2 273 ? 128.350 152.045 181.299 1.00 32.26  ? 255 LEU B N   1 
ATOM   3994 C  CA  . LEU B 2 273 ? 129.360 151.798 182.323 1.00 34.08  ? 255 LEU B CA  1 
ATOM   3995 C  C   . LEU B 2 273 ? 128.835 152.097 183.720 1.00 35.88  ? 255 LEU B C   1 
ATOM   3996 O  O   . LEU B 2 273 ? 129.124 151.358 184.666 1.00 40.22  ? 255 LEU B O   1 
ATOM   3997 C  CB  . LEU B 2 273 ? 130.610 152.631 182.049 1.00 34.92  ? 255 LEU B CB  1 
ATOM   3998 C  CG  . LEU B 2 273 ? 131.357 152.448 180.734 1.00 31.09  ? 255 LEU B CG  1 
ATOM   3999 C  CD1 . LEU B 2 273 ? 132.734 153.032 180.870 1.00 31.99  ? 255 LEU B CD1 1 
ATOM   4000 C  CD2 . LEU B 2 273 ? 131.440 150.999 180.359 1.00 30.03  ? 255 LEU B CD2 1 
ATOM   4001 N  N   . ARG B 2 274 ? 128.084 153.187 183.879 1.00 43.94  ? 256 ARG B N   1 
ATOM   4002 C  CA  . ARG B 2 274 ? 127.656 153.599 185.212 1.00 44.67  ? 256 ARG B CA  1 
ATOM   4003 C  C   . ARG B 2 274 ? 126.498 152.762 185.741 1.00 45.00  ? 256 ARG B C   1 
ATOM   4004 O  O   . ARG B 2 274 ? 126.420 152.523 186.949 1.00 46.63  ? 256 ARG B O   1 
ATOM   4005 C  CB  . ARG B 2 274 ? 127.288 155.083 185.210 1.00 45.13  ? 256 ARG B CB  1 
ATOM   4006 C  CG  . ARG B 2 274 ? 128.496 156.005 185.303 1.00 44.59  ? 256 ARG B CG  1 
ATOM   4007 C  CD  . ARG B 2 274 ? 128.099 157.464 185.189 1.00 43.31  ? 256 ARG B CD  1 
ATOM   4008 N  NE  . ARG B 2 274 ? 127.432 157.747 183.926 1.00 47.17  ? 256 ARG B NE  1 
ATOM   4009 C  CZ  . ARG B 2 274 ? 126.650 158.795 183.712 1.00 48.76  ? 256 ARG B CZ  1 
ATOM   4010 N  NH1 . ARG B 2 274 ? 126.417 159.687 184.660 1.00 45.53  ? 256 ARG B NH1 1 
ATOM   4011 N  NH2 . ARG B 2 274 ? 126.085 158.950 182.518 1.00 47.51  ? 256 ARG B NH2 1 
ATOM   4012 N  N   . ALA B 2 275 ? 125.589 152.320 184.871 1.00 44.63  ? 257 ALA B N   1 
ATOM   4013 C  CA  . ALA B 2 275 ? 124.522 151.425 185.300 1.00 45.80  ? 257 ALA B CA  1 
ATOM   4014 C  C   . ALA B 2 275 ? 124.953 149.968 185.300 1.00 46.67  ? 257 ALA B C   1 
ATOM   4015 O  O   . ALA B 2 275 ? 124.270 149.137 185.907 1.00 50.19  ? 257 ALA B O   1 
ATOM   4016 C  CB  . ALA B 2 275 ? 123.291 151.596 184.410 1.00 47.30  ? 257 ALA B CB  1 
ATOM   4017 N  N   . ASP B 2 276 ? 126.059 149.645 184.629 1.00 43.93  ? 258 ASP B N   1 
ATOM   4018 C  CA  . ASP B 2 276 ? 126.673 148.318 184.683 1.00 42.72  ? 258 ASP B CA  1 
ATOM   4019 C  C   . ASP B 2 276 ? 125.762 147.235 184.110 1.00 41.46  ? 258 ASP B C   1 
ATOM   4020 O  O   . ASP B 2 276 ? 125.726 146.110 184.609 1.00 49.26  ? 258 ASP B O   1 
ATOM   4021 C  CB  . ASP B 2 276 ? 127.090 147.970 186.114 1.00 42.12  ? 258 ASP B CB  1 
ATOM   4022 C  CG  . ASP B 2 276 ? 128.202 146.944 186.167 1.00 48.78  ? 258 ASP B CG  1 
ATOM   4023 O  OD1 . ASP B 2 276 ? 129.054 146.936 185.258 1.00 51.38  ? 258 ASP B OD1 1 
ATOM   4024 O  OD2 . ASP B 2 276 ? 128.230 146.143 187.123 1.00 50.17  ? 258 ASP B OD2 1 
ATOM   4025 N  N   . GLN B 2 277 ? 125.029 147.560 183.047 1.00 32.82  ? 259 GLN B N   1 
ATOM   4026 C  CA  . GLN B 2 277 ? 124.176 146.569 182.404 1.00 34.06  ? 259 GLN B CA  1 
ATOM   4027 C  C   . GLN B 2 277 ? 123.824 147.033 180.997 1.00 37.00  ? 259 GLN B C   1 
ATOM   4028 O  O   . GLN B 2 277 ? 124.100 148.166 180.605 1.00 46.29  ? 259 GLN B O   1 
ATOM   4029 C  CB  . GLN B 2 277 ? 122.913 146.298 183.226 1.00 35.54  ? 259 GLN B CB  1 
ATOM   4030 C  CG  . GLN B 2 277 ? 122.016 147.493 183.398 1.00 36.74  ? 259 GLN B CG  1 
ATOM   4031 C  CD  . GLN B 2 277 ? 121.083 147.349 184.576 1.00 39.05  ? 259 GLN B CD  1 
ATOM   4032 O  OE1 . GLN B 2 277 ? 119.985 146.812 184.450 1.00 37.40  ? 259 GLN B OE1 1 
ATOM   4033 N  NE2 . GLN B 2 277 ? 121.514 147.835 185.732 1.00 40.30  ? 259 GLN B NE2 1 
ATOM   4034 N  N   . GLU B 2 278 ? 123.204 146.128 180.246 1.00 32.07  ? 260 GLU B N   1 
ATOM   4035 C  CA  . GLU B 2 278 ? 122.868 146.361 178.849 1.00 27.83  ? 260 GLU B CA  1 
ATOM   4036 C  C   . GLU B 2 278 ? 121.587 147.174 178.721 1.00 32.07  ? 260 GLU B C   1 
ATOM   4037 O  O   . GLU B 2 278 ? 120.615 146.944 179.446 1.00 37.48  ? 260 GLU B O   1 
ATOM   4038 C  CB  . GLU B 2 278 ? 122.721 145.020 178.129 1.00 28.80  ? 260 GLU B CB  1 
ATOM   4039 C  CG  . GLU B 2 278 ? 121.855 145.037 176.896 1.00 36.26  ? 260 GLU B CG  1 
ATOM   4040 C  CD  . GLU B 2 278 ? 121.205 143.697 176.632 1.00 41.83  ? 260 GLU B CD  1 
ATOM   4041 O  OE1 . GLU B 2 278 ? 121.648 142.693 177.224 1.00 33.92  ? 260 GLU B OE1 1 
ATOM   4042 O  OE2 . GLU B 2 278 ? 120.243 143.650 175.839 1.00 42.42  ? 260 GLU B OE2 1 
ATOM   4043 N  N   . LEU B 2 279 ? 121.584 148.122 177.782 1.00 25.62  ? 261 LEU B N   1 
ATOM   4044 C  CA  . LEU B 2 279 ? 120.479 149.057 177.600 1.00 26.53  ? 261 LEU B CA  1 
ATOM   4045 C  C   . LEU B 2 279 ? 119.618 148.755 176.383 1.00 25.80  ? 261 LEU B C   1 
ATOM   4046 O  O   . LEU B 2 279 ? 118.391 148.750 176.486 1.00 32.02  ? 261 LEU B O   1 
ATOM   4047 C  CB  . LEU B 2 279 ? 121.014 150.492 177.490 1.00 33.22  ? 261 LEU B CB  1 
ATOM   4048 C  CG  . LEU B 2 279 ? 121.550 151.200 178.730 1.00 29.90  ? 261 LEU B CG  1 
ATOM   4049 C  CD1 . LEU B 2 279 ? 121.589 152.691 178.499 1.00 29.04  ? 261 LEU B CD1 1 
ATOM   4050 C  CD2 . LEU B 2 279 ? 120.701 150.879 179.924 1.00 30.59  ? 261 LEU B CD2 1 
ATOM   4051 N  N   . MET B 2 280 ? 120.227 148.521 175.224 1.00 24.03  ? 262 MET B N   1 
ATOM   4052 C  CA  . MET B 2 280 ? 119.499 148.387 173.972 1.00 24.02  ? 262 MET B CA  1 
ATOM   4053 C  C   . MET B 2 280 ? 120.060 147.227 173.167 1.00 23.32  ? 262 MET B C   1 
ATOM   4054 O  O   . MET B 2 280 ? 121.253 146.928 173.235 1.00 30.97  ? 262 MET B O   1 
ATOM   4055 C  CB  . MET B 2 280 ? 119.583 149.672 173.140 1.00 29.23  ? 262 MET B CB  1 
ATOM   4056 C  CG  . MET B 2 280 ? 118.503 149.827 172.079 1.00 28.66  ? 262 MET B CG  1 
ATOM   4057 S  SD  . MET B 2 280 ? 117.134 150.892 172.554 1.00 39.31  ? 262 MET B SD  1 
ATOM   4058 C  CE  . MET B 2 280 ? 115.816 149.695 172.692 1.00 33.02  ? 262 MET B CE  1 
ATOM   4059 N  N   . THR B 2 281 ? 119.183 146.588 172.393 1.00 19.52  ? 263 THR B N   1 
ATOM   4060 C  CA  . THR B 2 281 ? 119.544 145.529 171.459 1.00 19.41  ? 263 THR B CA  1 
ATOM   4061 C  C   . THR B 2 281 ? 119.087 145.912 170.059 1.00 22.45  ? 263 THR B C   1 
ATOM   4062 O  O   . THR B 2 281 ? 117.910 146.221 169.848 1.00 21.81  ? 263 THR B O   1 
ATOM   4063 C  CB  . THR B 2 281 ? 118.911 144.194 171.851 1.00 19.21  ? 263 THR B CB  1 
ATOM   4064 O  OG1 . THR B 2 281 ? 119.095 143.966 173.251 1.00 26.76  ? 263 THR B OG1 1 
ATOM   4065 C  CG2 . THR B 2 281 ? 119.538 143.060 171.070 1.00 16.07  ? 263 THR B CG2 1 
ATOM   4066 N  N   . TYR B 2 282 ? 120.010 145.872 169.107 1.00 15.52  ? 264 TYR B N   1 
ATOM   4067 C  CA  . TYR B 2 282 ? 119.751 146.222 167.715 1.00 9.66   ? 264 TYR B CA  1 
ATOM   4068 C  C   . TYR B 2 282 ? 119.791 144.935 166.902 1.00 17.01  ? 264 TYR B C   1 
ATOM   4069 O  O   . TYR B 2 282 ? 120.869 144.435 166.565 1.00 25.64  ? 264 TYR B O   1 
ATOM   4070 C  CB  . TYR B 2 282 ? 120.767 147.246 167.219 1.00 16.85  ? 264 TYR B CB  1 
ATOM   4071 C  CG  . TYR B 2 282 ? 120.989 148.387 168.185 1.00 24.29  ? 264 TYR B CG  1 
ATOM   4072 C  CD1 . TYR B 2 282 ? 120.069 149.409 168.300 1.00 20.52  ? 264 TYR B CD1 1 
ATOM   4073 C  CD2 . TYR B 2 282 ? 122.114 148.433 168.990 1.00 21.51  ? 264 TYR B CD2 1 
ATOM   4074 C  CE1 . TYR B 2 282 ? 120.263 150.433 169.183 1.00 17.25  ? 264 TYR B CE1 1 
ATOM   4075 C  CE2 . TYR B 2 282 ? 122.313 149.455 169.875 1.00 12.58  ? 264 TYR B CE2 1 
ATOM   4076 C  CZ  . TYR B 2 282 ? 121.384 150.450 169.970 1.00 15.74  ? 264 TYR B CZ  1 
ATOM   4077 O  OH  . TYR B 2 282 ? 121.580 151.477 170.852 1.00 26.15  ? 264 TYR B OH  1 
ATOM   4078 N  N   . SER B 2 283 ? 118.607 144.401 166.600 1.00 26.05  ? 265 SER B N   1 
ATOM   4079 C  CA  . SER B 2 283 ? 118.460 143.129 165.909 1.00 25.54  ? 265 SER B CA  1 
ATOM   4080 C  C   . SER B 2 283 ? 117.214 143.158 165.040 1.00 33.52  ? 265 SER B C   1 
ATOM   4081 O  O   . SER B 2 283 ? 116.263 143.892 165.310 1.00 38.61  ? 265 SER B O   1 
ATOM   4082 C  CB  . SER B 2 283 ? 118.356 141.968 166.891 1.00 31.17  ? 265 SER B CB  1 
ATOM   4083 O  OG  . SER B 2 283 ? 117.158 142.053 167.638 1.00 36.60  ? 265 SER B OG  1 
ATOM   4084 N  N   . HIS B 2 284 ? 117.220 142.322 164.005 1.00 47.11  ? 266 HIS B N   1 
ATOM   4085 C  CA  . HIS B 2 284 ? 116.094 142.194 163.093 1.00 46.92  ? 266 HIS B CA  1 
ATOM   4086 C  C   . HIS B 2 284 ? 115.852 140.721 162.801 1.00 48.76  ? 266 HIS B C   1 
ATOM   4087 O  O   . HIS B 2 284 ? 116.750 139.887 162.927 1.00 51.52  ? 266 HIS B O   1 
ATOM   4088 C  CB  . HIS B 2 284 ? 116.334 142.960 161.788 1.00 48.11  ? 266 HIS B CB  1 
ATOM   4089 C  CG  . HIS B 2 284 ? 115.082 143.279 161.035 1.00 51.57  ? 266 HIS B CG  1 
ATOM   4090 N  ND1 . HIS B 2 284 ? 114.867 142.864 159.739 1.00 51.36  ? 266 HIS B ND1 1 
ATOM   4091 C  CD2 . HIS B 2 284 ? 113.975 143.969 161.397 1.00 50.32  ? 266 HIS B CD2 1 
ATOM   4092 C  CE1 . HIS B 2 284 ? 113.684 143.287 159.334 1.00 53.08  ? 266 HIS B CE1 1 
ATOM   4093 N  NE2 . HIS B 2 284 ? 113.122 143.960 160.322 1.00 55.11  ? 266 HIS B NE2 1 
ATOM   4094 N  N   . ASP B 2 285 ? 114.620 140.407 162.403 1.00 53.13  ? 267 ASP B N   1 
ATOM   4095 C  CA  . ASP B 2 285 ? 114.245 139.017 162.169 1.00 54.02  ? 267 ASP B CA  1 
ATOM   4096 C  C   . ASP B 2 285 ? 114.852 138.446 160.894 1.00 52.16  ? 267 ASP B C   1 
ATOM   4097 O  O   . ASP B 2 285 ? 114.983 137.225 160.782 1.00 53.85  ? 267 ASP B O   1 
ATOM   4098 C  CB  . ASP B 2 285 ? 112.724 138.888 162.119 1.00 52.71  ? 267 ASP B CB  1 
ATOM   4099 C  CG  . ASP B 2 285 ? 112.126 138.559 163.467 1.00 56.75  ? 267 ASP B CG  1 
ATOM   4100 O  OD1 . ASP B 2 285 ? 112.200 137.383 163.878 1.00 58.13  ? 267 ASP B OD1 1 
ATOM   4101 O  OD2 . ASP B 2 285 ? 111.583 139.475 164.119 1.00 57.79  ? 267 ASP B OD2 1 
ATOM   4102 N  N   . ASN B 2 286 ? 115.215 139.291 159.935 1.00 51.49  ? 268 ASN B N   1 
ATOM   4103 C  CA  . ASN B 2 286 ? 115.758 138.843 158.662 1.00 52.45  ? 268 ASN B CA  1 
ATOM   4104 C  C   . ASN B 2 286 ? 117.278 138.868 158.617 1.00 52.86  ? 268 ASN B C   1 
ATOM   4105 O  O   . ASN B 2 286 ? 117.856 138.550 157.574 1.00 49.21  ? 268 ASN B O   1 
ATOM   4106 C  CB  . ASN B 2 286 ? 115.202 139.702 157.525 1.00 52.12  ? 268 ASN B CB  1 
ATOM   4107 C  CG  . ASN B 2 286 ? 113.722 139.487 157.307 1.00 55.05  ? 268 ASN B CG  1 
ATOM   4108 O  OD1 . ASN B 2 286 ? 112.951 139.400 158.260 1.00 55.84  ? 268 ASN B OD1 1 
ATOM   4109 N  ND2 . ASN B 2 286 ? 113.315 139.400 156.046 1.00 57.17  ? 268 ASN B ND2 1 
ATOM   4110 N  N   . ILE B 2 287 ? 117.935 139.242 159.709 1.00 42.31  ? 269 ILE B N   1 
ATOM   4111 C  CA  . ILE B 2 287 ? 119.390 139.298 159.780 1.00 40.26  ? 269 ILE B CA  1 
ATOM   4112 C  C   . ILE B 2 287 ? 119.850 138.074 160.557 1.00 39.76  ? 269 ILE B C   1 
ATOM   4113 O  O   . ILE B 2 287 ? 119.572 137.947 161.753 1.00 41.17  ? 269 ILE B O   1 
ATOM   4114 C  CB  . ILE B 2 287 ? 119.878 140.597 160.435 1.00 40.12  ? 269 ILE B CB  1 
ATOM   4115 C  CG1 . ILE B 2 287 ? 119.186 141.804 159.801 1.00 43.17  ? 269 ILE B CG1 1 
ATOM   4116 C  CG2 . ILE B 2 287 ? 121.378 140.728 160.295 1.00 33.33  ? 269 ILE B CG2 1 
ATOM   4117 C  CD1 . ILE B 2 287 ? 119.723 143.127 160.264 1.00 37.69  ? 269 ILE B CD1 1 
ATOM   4118 N  N   . ILE B 2 288 ? 120.542 137.164 159.878 1.00 32.95  ? 270 ILE B N   1 
ATOM   4119 C  CA  . ILE B 2 288 ? 120.981 135.917 160.489 1.00 27.03  ? 270 ILE B CA  1 
ATOM   4120 C  C   . ILE B 2 288 ? 122.469 135.713 160.237 1.00 30.12  ? 270 ILE B C   1 
ATOM   4121 O  O   . ILE B 2 288 ? 122.959 134.580 160.225 1.00 40.90  ? 270 ILE B O   1 
ATOM   4122 C  CB  . ILE B 2 288 ? 120.153 134.722 159.977 1.00 29.93  ? 270 ILE B CB  1 
ATOM   4123 C  CG1 . ILE B 2 288 ? 120.339 134.531 158.472 1.00 30.68  ? 270 ILE B CG1 1 
ATOM   4124 C  CG2 . ILE B 2 288 ? 118.683 134.891 160.325 1.00 27.73  ? 270 ILE B CG2 1 
ATOM   4125 C  CD1 . ILE B 2 288 ? 120.693 133.121 158.079 1.00 30.71  ? 270 ILE B CD1 1 
ATOM   4126 N  N   . CYS B 2 289 ? 123.196 136.805 160.031 1.00 16.31  ? 271 CYS B N   1 
ATOM   4127 C  CA  . CYS B 2 289 ? 124.640 136.771 159.870 1.00 16.99  ? 271 CYS B CA  1 
ATOM   4128 C  C   . CYS B 2 289 ? 125.292 137.598 160.971 1.00 22.24  ? 271 CYS B C   1 
ATOM   4129 O  O   . CYS B 2 289 ? 124.650 138.433 161.607 1.00 23.53  ? 271 CYS B O   1 
ATOM   4130 C  CB  . CYS B 2 289 ? 125.063 137.292 158.491 1.00 22.21  ? 271 CYS B CB  1 
ATOM   4131 S  SG  . CYS B 2 289 ? 124.475 138.947 158.100 1.00 37.05  ? 271 CYS B SG  1 
ATOM   4132 N  N   . GLY B 2 290 ? 126.576 137.357 161.194 1.00 15.87  ? 272 GLY B N   1 
ATOM   4133 C  CA  . GLY B 2 290 ? 127.275 138.045 162.253 1.00 11.87  ? 272 GLY B CA  1 
ATOM   4134 C  C   . GLY B 2 290 ? 127.714 139.443 161.873 1.00 15.65  ? 272 GLY B C   1 
ATOM   4135 O  O   . GLY B 2 290 ? 127.908 139.770 160.708 1.00 16.83  ? 272 GLY B O   1 
ATOM   4136 N  N   . ILE B 2 291 ? 127.883 140.272 162.895 1.00 12.98  ? 273 ILE B N   1 
ATOM   4137 C  CA  . ILE B 2 291 ? 128.369 141.637 162.737 1.00 0.00   ? 273 ILE B CA  1 
ATOM   4138 C  C   . ILE B 2 291 ? 129.888 141.620 162.813 1.00 11.55  ? 273 ILE B C   1 
ATOM   4139 O  O   . ILE B 2 291 ? 130.466 141.076 163.757 1.00 23.51  ? 273 ILE B O   1 
ATOM   4140 C  CB  . ILE B 2 291 ? 127.774 142.558 163.812 1.00 8.82   ? 273 ILE B CB  1 
ATOM   4141 C  CG1 . ILE B 2 291 ? 126.297 142.800 163.552 1.00 12.58  ? 273 ILE B CG1 1 
ATOM   4142 C  CG2 . ILE B 2 291 ? 128.483 143.884 163.828 1.00 11.43  ? 273 ILE B CG2 1 
ATOM   4143 C  CD1 . ILE B 2 291 ? 125.390 141.854 164.243 1.00 13.81  ? 273 ILE B CD1 1 
ATOM   4144 N  N   . THR B 2 292 ? 130.538 142.211 161.816 1.00 12.14  ? 274 THR B N   1 
ATOM   4145 C  CA  . THR B 2 292 ? 131.990 142.189 161.725 1.00 0.00   ? 274 THR B CA  1 
ATOM   4146 C  C   . THR B 2 292 ? 132.660 143.465 162.218 1.00 10.00  ? 274 THR B C   1 
ATOM   4147 O  O   . THR B 2 292 ? 133.862 143.441 162.496 1.00 20.29  ? 274 THR B O   1 
ATOM   4148 C  CB  . THR B 2 292 ? 132.420 141.936 160.278 1.00 7.22   ? 274 THR B CB  1 
ATOM   4149 O  OG1 . THR B 2 292 ? 131.898 142.967 159.438 1.00 12.14  ? 274 THR B OG1 1 
ATOM   4150 C  CG2 . THR B 2 292 ? 131.885 140.624 159.800 1.00 5.96   ? 274 THR B CG2 1 
ATOM   4151 N  N   . SER B 2 293 ? 131.923 144.568 162.332 1.00 7.85   ? 275 SER B N   1 
ATOM   4152 C  CA  . SER B 2 293 ? 132.495 145.855 162.689 1.00 1.98   ? 275 SER B CA  1 
ATOM   4153 C  C   . SER B 2 293 ? 131.377 146.790 163.113 1.00 8.57   ? 275 SER B C   1 
ATOM   4154 O  O   . SER B 2 293 ? 130.261 146.703 162.604 1.00 10.83  ? 275 SER B O   1 
ATOM   4155 C  CB  . SER B 2 293 ? 133.272 146.450 161.521 1.00 5.02   ? 275 SER B CB  1 
ATOM   4156 O  OG  . SER B 2 293 ? 132.658 146.101 160.298 1.00 16.51  ? 275 SER B OG  1 
ATOM   4157 N  N   . VAL B 2 294 ? 131.682 147.673 164.064 1.00 14.49  ? 276 VAL B N   1 
ATOM   4158 C  CA  . VAL B 2 294 ? 130.743 148.689 164.524 1.00 11.00  ? 276 VAL B CA  1 
ATOM   4159 C  C   . VAL B 2 294 ? 131.480 150.015 164.636 1.00 10.71  ? 276 VAL B C   1 
ATOM   4160 O  O   . VAL B 2 294 ? 132.698 150.055 164.820 1.00 21.57  ? 276 VAL B O   1 
ATOM   4161 C  CB  . VAL B 2 294 ? 130.075 148.332 165.878 1.00 6.17   ? 276 VAL B CB  1 
ATOM   4162 C  CG1 . VAL B 2 294 ? 129.200 147.112 165.750 1.00 10.63  ? 276 VAL B CG1 1 
ATOM   4163 C  CG2 . VAL B 2 294 ? 131.106 148.119 166.944 1.00 9.17   ? 276 VAL B CG2 1 
ATOM   4164 N  N   . SER B 2 295 ? 130.727 151.106 164.520 1.00 10.34  ? 277 SER B N   1 
ATOM   4165 C  CA  . SER B 2 295 ? 131.266 152.444 164.714 1.00 9.19   ? 277 SER B CA  1 
ATOM   4166 C  C   . SER B 2 295 ? 130.126 153.375 165.084 1.00 10.97  ? 277 SER B C   1 
ATOM   4167 O  O   . SER B 2 295 ? 128.954 153.055 164.891 1.00 14.17  ? 277 SER B O   1 
ATOM   4168 C  CB  . SER B 2 295 ? 131.992 152.953 163.471 1.00 13.60  ? 277 SER B CB  1 
ATOM   4169 O  OG  . SER B 2 295 ? 132.466 154.271 163.671 1.00 22.91  ? 277 SER B OG  1 
ATOM   4170 N  N   . PHE B 2 296 ? 130.487 154.527 165.632 1.00 10.62  ? 278 PHE B N   1 
ATOM   4171 C  CA  . PHE B 2 296 ? 129.534 155.534 166.074 1.00 9.74   ? 278 PHE B CA  1 
ATOM   4172 C  C   . PHE B 2 296 ? 129.772 156.822 165.302 1.00 24.20  ? 278 PHE B C   1 
ATOM   4173 O  O   . PHE B 2 296 ? 130.919 157.216 165.080 1.00 30.05  ? 278 PHE B O   1 
ATOM   4174 C  CB  . PHE B 2 296 ? 129.674 155.811 167.575 1.00 9.88   ? 278 PHE B CB  1 
ATOM   4175 C  CG  . PHE B 2 296 ? 128.698 155.068 168.433 1.00 15.95  ? 278 PHE B CG  1 
ATOM   4176 C  CD1 . PHE B 2 296 ? 127.356 155.380 168.407 1.00 22.25  ? 278 PHE B CD1 1 
ATOM   4177 C  CD2 . PHE B 2 296 ? 129.131 154.071 169.285 1.00 15.44  ? 278 PHE B CD2 1 
ATOM   4178 C  CE1 . PHE B 2 296 ? 126.462 154.700 169.205 1.00 19.74  ? 278 PHE B CE1 1 
ATOM   4179 C  CE2 . PHE B 2 296 ? 128.244 153.393 170.082 1.00 16.07  ? 278 PHE B CE2 1 
ATOM   4180 C  CZ  . PHE B 2 296 ? 126.908 153.707 170.043 1.00 15.89  ? 278 PHE B CZ  1 
ATOM   4181 N  N   . SER B 2 297 ? 128.691 157.482 164.902 1.00 19.05  ? 279 SER B N   1 
ATOM   4182 C  CA  . SER B 2 297 ? 128.811 158.783 164.270 1.00 9.51   ? 279 SER B CA  1 
ATOM   4183 C  C   . SER B 2 297 ? 129.200 159.829 165.313 1.00 15.13  ? 279 SER B C   1 
ATOM   4184 O  O   . SER B 2 297 ? 129.381 159.532 166.494 1.00 18.22  ? 279 SER B O   1 
ATOM   4185 C  CB  . SER B 2 297 ? 127.515 159.146 163.557 1.00 20.88  ? 279 SER B CB  1 
ATOM   4186 O  OG  . SER B 2 297 ? 126.448 159.284 164.473 1.00 29.12  ? 279 SER B OG  1 
ATOM   4187 N  N   . LYS B 2 298 ? 129.330 161.079 164.866 1.00 21.54  ? 280 LYS B N   1 
ATOM   4188 C  CA  . LYS B 2 298 ? 129.970 162.102 165.689 1.00 14.32  ? 280 LYS B CA  1 
ATOM   4189 C  C   . LYS B 2 298 ? 129.176 162.400 166.953 1.00 17.53  ? 280 LYS B C   1 
ATOM   4190 O  O   . LYS B 2 298 ? 129.760 162.625 168.017 1.00 24.41  ? 280 LYS B O   1 
ATOM   4191 C  CB  . LYS B 2 298 ? 130.171 163.379 164.877 1.00 23.07  ? 280 LYS B CB  1 
ATOM   4192 C  CG  . LYS B 2 298 ? 130.807 164.501 165.662 1.00 25.66  ? 280 LYS B CG  1 
ATOM   4193 C  CD  . LYS B 2 298 ? 131.444 165.525 164.758 1.00 23.36  ? 280 LYS B CD  1 
ATOM   4194 C  CE  . LYS B 2 298 ? 132.330 166.466 165.547 1.00 23.10  ? 280 LYS B CE  1 
ATOM   4195 N  NZ  . LYS B 2 298 ? 133.450 165.750 166.208 1.00 19.82  ? 280 LYS B NZ  1 
ATOM   4196 N  N   . SER B 2 299 ? 127.851 162.429 166.859 1.00 22.67  ? 281 SER B N   1 
ATOM   4197 C  CA  . SER B 2 299 ? 127.018 162.741 168.011 1.00 24.47  ? 281 SER B CA  1 
ATOM   4198 C  C   . SER B 2 299 ? 126.556 161.511 168.771 1.00 27.69  ? 281 SER B C   1 
ATOM   4199 O  O   . SER B 2 299 ? 125.933 161.656 169.826 1.00 28.17  ? 281 SER B O   1 
ATOM   4200 C  CB  . SER B 2 299 ? 125.795 163.541 167.578 1.00 23.69  ? 281 SER B CB  1 
ATOM   4201 O  OG  . SER B 2 299 ? 125.295 163.065 166.347 1.00 30.68  ? 281 SER B OG  1 
ATOM   4202 N  N   . GLY B 2 300 ? 126.848 160.314 168.273 1.00 26.45  ? 282 GLY B N   1 
ATOM   4203 C  CA  . GLY B 2 300 ? 126.357 159.100 168.881 1.00 19.72  ? 282 GLY B CA  1 
ATOM   4204 C  C   . GLY B 2 300 ? 124.913 158.781 168.587 1.00 24.90  ? 282 GLY B C   1 
ATOM   4205 O  O   . GLY B 2 300 ? 124.343 157.914 169.253 1.00 36.74  ? 282 GLY B O   1 
ATOM   4206 N  N   . ARG B 2 301 ? 124.297 159.455 167.622 1.00 24.65  ? 283 ARG B N   1 
ATOM   4207 C  CA  . ARG B 2 301 ? 122.903 159.211 167.284 1.00 23.55  ? 283 ARG B CA  1 
ATOM   4208 C  C   . ARG B 2 301 ? 122.733 158.116 166.249 1.00 27.04  ? 283 ARG B C   1 
ATOM   4209 O  O   . ARG B 2 301 ? 121.631 157.579 166.109 1.00 33.51  ? 283 ARG B O   1 
ATOM   4210 C  CB  . ARG B 2 301 ? 122.256 160.499 166.773 1.00 28.01  ? 283 ARG B CB  1 
ATOM   4211 C  CG  . ARG B 2 301 ? 120.756 160.423 166.557 1.00 26.45  ? 283 ARG B CG  1 
ATOM   4212 C  CD  . ARG B 2 301 ? 120.027 159.989 167.804 1.00 23.64  ? 283 ARG B CD  1 
ATOM   4213 N  NE  . ARG B 2 301 ? 118.741 159.386 167.487 1.00 26.09  ? 283 ARG B NE  1 
ATOM   4214 C  CZ  . ARG B 2 301 ? 117.614 160.064 167.332 1.00 30.61  ? 283 ARG B CZ  1 
ATOM   4215 N  NH1 . ARG B 2 301 ? 117.578 161.378 167.457 1.00 25.00  ? 283 ARG B NH1 1 
ATOM   4216 N  NH2 . ARG B 2 301 ? 116.497 159.407 167.043 1.00 35.23  ? 283 ARG B NH2 1 
ATOM   4217 N  N   . LEU B 2 302 ? 123.790 157.766 165.532 1.00 18.05  ? 284 LEU B N   1 
ATOM   4218 C  CA  . LEU B 2 302 ? 123.749 156.686 164.563 1.00 19.31  ? 284 LEU B CA  1 
ATOM   4219 C  C   . LEU B 2 302 ? 124.792 155.647 164.932 1.00 17.07  ? 284 LEU B C   1 
ATOM   4220 O  O   . LEU B 2 302 ? 125.848 155.969 165.475 1.00 15.57  ? 284 LEU B O   1 
ATOM   4221 C  CB  . LEU B 2 302 ? 123.998 157.188 163.132 1.00 26.20  ? 284 LEU B CB  1 
ATOM   4222 C  CG  . LEU B 2 302 ? 123.031 158.190 162.495 1.00 21.51  ? 284 LEU B CG  1 
ATOM   4223 C  CD1 . LEU B 2 302 ? 123.530 158.574 161.127 1.00 17.68  ? 284 LEU B CD1 1 
ATOM   4224 C  CD2 . LEU B 2 302 ? 121.630 157.632 162.408 1.00 15.21  ? 284 LEU B CD2 1 
ATOM   4225 N  N   . LEU B 2 303 ? 124.474 154.393 164.645 1.00 23.87  ? 285 LEU B N   1 
ATOM   4226 C  CA  . LEU B 2 303 ? 125.361 153.265 164.896 1.00 23.64  ? 285 LEU B CA  1 
ATOM   4227 C  C   . LEU B 2 303 ? 125.538 152.523 163.578 1.00 17.77  ? 285 LEU B C   1 
ATOM   4228 O  O   . LEU B 2 303 ? 124.579 151.960 163.046 1.00 15.52  ? 285 LEU B O   1 
ATOM   4229 C  CB  . LEU B 2 303 ? 124.789 152.364 165.990 1.00 12.64  ? 285 LEU B CB  1 
ATOM   4230 C  CG  . LEU B 2 303 ? 125.492 151.059 166.355 1.00 16.26  ? 285 LEU B CG  1 
ATOM   4231 C  CD1 . LEU B 2 303 ? 126.961 151.272 166.633 1.00 13.39  ? 285 LEU B CD1 1 
ATOM   4232 C  CD2 . LEU B 2 303 ? 124.816 150.455 167.547 1.00 14.84  ? 285 LEU B CD2 1 
ATOM   4233 N  N   . LEU B 2 304 ? 126.749 152.550 163.043 1.00 8.51   ? 286 LEU B N   1 
ATOM   4234 C  CA  . LEU B 2 304 ? 127.059 151.909 161.776 1.00 5.13   ? 286 LEU B CA  1 
ATOM   4235 C  C   . LEU B 2 304 ? 127.565 150.503 162.054 1.00 16.64  ? 286 LEU B C   1 
ATOM   4236 O  O   . LEU B 2 304 ? 128.417 150.315 162.923 1.00 18.97  ? 286 LEU B O   1 
ATOM   4237 C  CB  . LEU B 2 304 ? 128.116 152.708 161.011 1.00 15.63  ? 286 LEU B CB  1 
ATOM   4238 C  CG  . LEU B 2 304 ? 127.882 154.062 160.328 1.00 17.38  ? 286 LEU B CG  1 
ATOM   4239 C  CD1 . LEU B 2 304 ? 127.105 153.880 159.056 1.00 15.55  ? 286 LEU B CD1 1 
ATOM   4240 C  CD2 . LEU B 2 304 ? 127.215 155.084 161.226 1.00 10.06  ? 286 LEU B CD2 1 
ATOM   4241 N  N   . ALA B 2 305 ? 127.050 149.519 161.324 1.00 18.21  ? 287 ALA B N   1 
ATOM   4242 C  CA  . ALA B 2 305 ? 127.420 148.135 161.588 1.00 6.89   ? 287 ALA B CA  1 
ATOM   4243 C  C   . ALA B 2 305 ? 127.590 147.372 160.287 1.00 13.55  ? 287 ALA B C   1 
ATOM   4244 O  O   . ALA B 2 305 ? 126.667 147.333 159.476 1.00 29.83  ? 287 ALA B O   1 
ATOM   4245 C  CB  . ALA B 2 305 ? 126.364 147.452 162.458 1.00 8.10   ? 287 ALA B CB  1 
ATOM   4246 N  N   . GLY B 2 306 ? 128.751 146.751 160.100 1.00 7.19   ? 288 GLY B N   1 
ATOM   4247 C  CA  . GLY B 2 306 ? 128.991 145.929 158.930 1.00 6.30   ? 288 GLY B CA  1 
ATOM   4248 C  C   . GLY B 2 306 ? 128.671 144.467 159.183 1.00 10.54  ? 288 GLY B C   1 
ATOM   4249 O  O   . GLY B 2 306 ? 128.837 143.966 160.283 1.00 15.95  ? 288 GLY B O   1 
ATOM   4250 N  N   . TYR B 2 307 ? 128.225 143.774 158.137 1.00 16.93  ? 289 TYR B N   1 
ATOM   4251 C  CA  . TYR B 2 307 ? 127.717 142.414 158.263 1.00 4.49   ? 289 TYR B CA  1 
ATOM   4252 C  C   . TYR B 2 307 ? 128.383 141.495 157.250 1.00 7.77   ? 289 TYR B C   1 
ATOM   4253 O  O   . TYR B 2 307 ? 129.164 141.923 156.400 1.00 6.51   ? 289 TYR B O   1 
ATOM   4254 C  CB  . TYR B 2 307 ? 126.196 142.368 158.078 1.00 5.98   ? 289 TYR B CB  1 
ATOM   4255 C  CG  . TYR B 2 307 ? 125.413 143.062 159.163 1.00 13.90  ? 289 TYR B CG  1 
ATOM   4256 C  CD1 . TYR B 2 307 ? 125.357 144.439 159.233 1.00 11.56  ? 289 TYR B CD1 1 
ATOM   4257 C  CD2 . TYR B 2 307 ? 124.721 142.338 160.108 1.00 14.14  ? 289 TYR B CD2 1 
ATOM   4258 C  CE1 . TYR B 2 307 ? 124.650 145.072 160.217 1.00 7.38   ? 289 TYR B CE1 1 
ATOM   4259 C  CE2 . TYR B 2 307 ? 124.008 142.966 161.091 1.00 12.79  ? 289 TYR B CE2 1 
ATOM   4260 C  CZ  . TYR B 2 307 ? 123.978 144.333 161.142 1.00 12.11  ? 289 TYR B CZ  1 
ATOM   4261 O  OH  . TYR B 2 307 ? 123.262 144.962 162.129 1.00 25.85  ? 289 TYR B OH  1 
ATOM   4262 N  N   . ASP B 2 308 ? 128.057 140.206 157.358 1.00 19.55  ? 290 ASP B N   1 
ATOM   4263 C  CA  . ASP B 2 308 ? 128.554 139.165 156.463 1.00 17.16  ? 290 ASP B CA  1 
ATOM   4264 C  C   . ASP B 2 308 ? 127.744 139.029 155.180 1.00 21.17  ? 290 ASP B C   1 
ATOM   4265 O  O   . ASP B 2 308 ? 128.214 138.381 154.241 1.00 19.32  ? 290 ASP B O   1 
ATOM   4266 C  CB  . ASP B 2 308 ? 128.565 137.817 157.186 1.00 15.58  ? 290 ASP B CB  1 
ATOM   4267 C  CG  . ASP B 2 308 ? 129.759 137.654 158.098 1.00 27.33  ? 290 ASP B CG  1 
ATOM   4268 O  OD1 . ASP B 2 308 ? 130.773 138.333 157.869 1.00 30.64  ? 290 ASP B OD1 1 
ATOM   4269 O  OD2 . ASP B 2 308 ? 129.687 136.846 159.043 1.00 25.23  ? 290 ASP B OD2 1 
ATOM   4270 N  N   . ASP B 2 309 ? 126.543 139.607 155.114 1.00 21.07  ? 291 ASP B N   1 
ATOM   4271 C  CA  . ASP B 2 309 ? 125.739 139.612 153.901 1.00 17.49  ? 291 ASP B CA  1 
ATOM   4272 C  C   . ASP B 2 309 ? 126.118 140.737 152.952 1.00 19.36  ? 291 ASP B C   1 
ATOM   4273 O  O   . ASP B 2 309 ? 125.320 141.091 152.078 1.00 26.98  ? 291 ASP B O   1 
ATOM   4274 C  CB  . ASP B 2 309 ? 124.252 139.691 154.249 1.00 19.56  ? 291 ASP B CB  1 
ATOM   4275 C  CG  . ASP B 2 309 ? 123.893 140.953 154.989 1.00 24.98  ? 291 ASP B CG  1 
ATOM   4276 O  OD1 . ASP B 2 309 ? 124.790 141.776 155.238 1.00 24.46  ? 291 ASP B OD1 1 
ATOM   4277 O  OD2 . ASP B 2 309 ? 122.706 141.127 155.329 1.00 32.14  ? 291 ASP B OD2 1 
ATOM   4278 N  N   . PHE B 2 310 ? 127.307 141.305 153.139 1.00 17.04  ? 292 PHE B N   1 
ATOM   4279 C  CA  . PHE B 2 310 ? 128.032 142.220 152.262 1.00 12.85  ? 292 PHE B CA  1 
ATOM   4280 C  C   . PHE B 2 310 ? 127.574 143.671 152.357 1.00 17.28  ? 292 PHE B C   1 
ATOM   4281 O  O   . PHE B 2 310 ? 128.099 144.495 151.609 1.00 18.76  ? 292 PHE B O   1 
ATOM   4282 C  CB  . PHE B 2 310 ? 127.973 141.807 150.783 1.00 15.35  ? 292 PHE B CB  1 
ATOM   4283 C  CG  . PHE B 2 310 ? 128.350 140.376 150.521 1.00 16.20  ? 292 PHE B CG  1 
ATOM   4284 C  CD1 . PHE B 2 310 ? 129.062 139.640 151.445 1.00 17.56  ? 292 PHE B CD1 1 
ATOM   4285 C  CD2 . PHE B 2 310 ? 127.995 139.770 149.335 1.00 18.29  ? 292 PHE B CD2 1 
ATOM   4286 C  CE1 . PHE B 2 310 ? 129.403 138.330 151.194 1.00 20.55  ? 292 PHE B CE1 1 
ATOM   4287 C  CE2 . PHE B 2 310 ? 128.337 138.465 149.080 1.00 22.19  ? 292 PHE B CE2 1 
ATOM   4288 C  CZ  . PHE B 2 310 ? 129.041 137.744 150.011 1.00 23.59  ? 292 PHE B CZ  1 
ATOM   4289 N  N   . ASN B 2 311 ? 126.640 144.027 153.234 1.00 15.10  ? 293 ASN B N   1 
ATOM   4290 C  CA  . ASN B 2 311 ? 126.215 145.416 153.338 1.00 25.24  ? 293 ASN B CA  1 
ATOM   4291 C  C   . ASN B 2 311 ? 126.131 145.852 154.792 1.00 19.47  ? 293 ASN B C   1 
ATOM   4292 O  O   . ASN B 2 311 ? 125.908 145.039 155.689 1.00 14.70  ? 293 ASN B O   1 
ATOM   4293 C  CB  . ASN B 2 311 ? 124.865 145.662 152.635 1.00 17.11  ? 293 ASN B CB  1 
ATOM   4294 C  CG  . ASN B 2 311 ? 123.782 144.718 153.080 1.00 21.53  ? 293 ASN B CG  1 
ATOM   4295 O  OD1 . ASN B 2 311 ? 123.461 144.631 154.260 1.00 22.91  ? 293 ASN B OD1 1 
ATOM   4296 N  ND2 . ASN B 2 311 ? 123.189 144.018 152.126 1.00 26.28  ? 293 ASN B ND2 1 
ATOM   4297 N  N   . CYS B 2 312 ? 126.312 147.150 155.013 1.00 14.70  ? 294 CYS B N   1 
ATOM   4298 C  CA  . CYS B 2 312 ? 126.247 147.741 156.339 1.00 10.00  ? 294 CYS B CA  1 
ATOM   4299 C  C   . CYS B 2 312 ? 124.859 148.300 156.608 1.00 13.99  ? 294 CYS B C   1 
ATOM   4300 O  O   . CYS B 2 312 ? 124.100 148.603 155.692 1.00 20.65  ? 294 CYS B O   1 
ATOM   4301 C  CB  . CYS B 2 312 ? 127.287 148.851 156.491 1.00 2.08   ? 294 CYS B CB  1 
ATOM   4302 S  SG  . CYS B 2 312 ? 128.779 148.604 155.536 1.00 39.77  ? 294 CYS B SG  1 
ATOM   4303 N  N   . ASN B 2 313 ? 124.541 148.451 157.886 1.00 15.92  ? 295 ASN B N   1 
ATOM   4304 C  CA  . ASN B 2 313 ? 123.276 149.022 158.318 1.00 15.36  ? 295 ASN B CA  1 
ATOM   4305 C  C   . ASN B 2 313 ? 123.530 150.204 159.240 1.00 15.38  ? 295 ASN B C   1 
ATOM   4306 O  O   . ASN B 2 313 ? 124.561 150.281 159.914 1.00 20.62  ? 295 ASN B O   1 
ATOM   4307 C  CB  . ASN B 2 313 ? 122.403 147.998 159.040 1.00 12.79  ? 295 ASN B CB  1 
ATOM   4308 C  CG  . ASN B 2 313 ? 121.801 146.987 158.106 1.00 22.01  ? 295 ASN B CG  1 
ATOM   4309 O  OD1 . ASN B 2 313 ? 122.076 146.992 156.913 1.00 29.71  ? 295 ASN B OD1 1 
ATOM   4310 N  ND2 . ASN B 2 313 ? 120.978 146.105 158.643 1.00 23.08  ? 295 ASN B ND2 1 
ATOM   4311 N  N   . VAL B 2 314 ? 122.575 151.126 159.255 1.00 9.61   ? 296 VAL B N   1 
ATOM   4312 C  CA  . VAL B 2 314 ? 122.600 152.294 160.122 1.00 12.37  ? 296 VAL B CA  1 
ATOM   4313 C  C   . VAL B 2 314 ? 121.458 152.150 161.113 1.00 15.81  ? 296 VAL B C   1 
ATOM   4314 O  O   . VAL B 2 314 ? 120.305 151.961 160.714 1.00 20.54  ? 296 VAL B O   1 
ATOM   4315 C  CB  . VAL B 2 314 ? 122.478 153.596 159.314 1.00 11.15  ? 296 VAL B CB  1 
ATOM   4316 C  CG1 . VAL B 2 314 ? 122.455 154.794 160.227 1.00 14.26  ? 296 VAL B CG1 1 
ATOM   4317 C  CG2 . VAL B 2 314 ? 123.613 153.708 158.323 1.00 11.81  ? 296 VAL B CG2 1 
ATOM   4318 N  N   . TRP B 2 315 ? 121.776 152.219 162.398 1.00 13.46  ? 297 TRP B N   1 
ATOM   4319 C  CA  . TRP B 2 315 ? 120.806 152.037 163.461 1.00 11.16  ? 297 TRP B CA  1 
ATOM   4320 C  C   . TRP B 2 315 ? 120.635 153.340 164.220 1.00 14.63  ? 297 TRP B C   1 
ATOM   4321 O  O   . TRP B 2 315 ? 121.608 154.047 164.476 1.00 24.52  ? 297 TRP B O   1 
ATOM   4322 C  CB  . TRP B 2 315 ? 121.251 150.935 164.427 1.00 23.50  ? 297 TRP B CB  1 
ATOM   4323 C  CG  . TRP B 2 315 ? 121.280 149.572 163.821 1.00 19.32  ? 297 TRP B CG  1 
ATOM   4324 C  CD1 . TRP B 2 315 ? 122.347 148.952 163.250 1.00 14.59  ? 297 TRP B CD1 1 
ATOM   4325 C  CD2 . TRP B 2 315 ? 120.187 148.659 163.726 1.00 13.98  ? 297 TRP B CD2 1 
ATOM   4326 N  NE1 . TRP B 2 315 ? 121.986 147.713 162.802 1.00 10.98  ? 297 TRP B NE1 1 
ATOM   4327 C  CE2 . TRP B 2 315 ? 120.661 147.510 163.081 1.00 11.47  ? 297 TRP B CE2 1 
ATOM   4328 C  CE3 . TRP B 2 315 ? 118.852 148.704 164.124 1.00 17.74  ? 297 TRP B CE3 1 
ATOM   4329 C  CZ2 . TRP B 2 315 ? 119.850 146.418 162.824 1.00 14.52  ? 297 TRP B CZ2 1 
ATOM   4330 C  CZ3 . TRP B 2 315 ? 118.055 147.620 163.871 1.00 20.89  ? 297 TRP B CZ3 1 
ATOM   4331 C  CH2 . TRP B 2 315 ? 118.552 146.494 163.225 1.00 15.85  ? 297 TRP B CH2 1 
ATOM   4332 N  N   . ASP B 2 316 ? 119.400 153.650 164.576 1.00 19.69  ? 298 ASP B N   1 
ATOM   4333 C  CA  . ASP B 2 316 ? 119.100 154.781 165.446 1.00 15.45  ? 298 ASP B CA  1 
ATOM   4334 C  C   . ASP B 2 316 ? 119.366 154.340 166.879 1.00 26.40  ? 298 ASP B C   1 
ATOM   4335 O  O   . ASP B 2 316 ? 118.529 153.689 167.504 1.00 34.53  ? 298 ASP B O   1 
ATOM   4336 C  CB  . ASP B 2 316 ? 117.659 155.225 165.248 1.00 16.10  ? 298 ASP B CB  1 
ATOM   4337 C  CG  . ASP B 2 316 ? 117.311 156.446 166.045 1.00 24.45  ? 298 ASP B CG  1 
ATOM   4338 O  OD1 . ASP B 2 316 ? 118.217 157.044 166.647 1.00 26.95  ? 298 ASP B OD1 1 
ATOM   4339 O  OD2 . ASP B 2 316 ? 116.124 156.818 166.066 1.00 30.88  ? 298 ASP B OD2 1 
ATOM   4340 N  N   . ALA B 2 317 ? 120.535 154.708 167.410 1.00 27.06  ? 299 ALA B N   1 
ATOM   4341 C  CA  . ALA B 2 317 ? 120.987 154.165 168.688 1.00 24.27  ? 299 ALA B CA  1 
ATOM   4342 C  C   . ALA B 2 317 ? 120.041 154.498 169.834 1.00 25.32  ? 299 ALA B C   1 
ATOM   4343 O  O   . ALA B 2 317 ? 120.011 153.777 170.835 1.00 27.67  ? 299 ALA B O   1 
ATOM   4344 C  CB  . ALA B 2 317 ? 122.390 154.675 169.002 1.00 16.93  ? 299 ALA B CB  1 
ATOM   4345 N  N   . LEU B 2 318 ? 119.274 155.576 169.724 1.00 32.05  ? 300 LEU B N   1 
ATOM   4346 C  CA  . LEU B 2 318 ? 118.337 155.948 170.776 1.00 33.39  ? 300 LEU B CA  1 
ATOM   4347 C  C   . LEU B 2 318 ? 116.985 155.265 170.644 1.00 33.25  ? 300 LEU B C   1 
ATOM   4348 O  O   . LEU B 2 318 ? 116.207 155.280 171.601 1.00 35.37  ? 300 LEU B O   1 
ATOM   4349 C  CB  . LEU B 2 318 ? 118.124 157.464 170.790 1.00 34.52  ? 300 LEU B CB  1 
ATOM   4350 C  CG  . LEU B 2 318 ? 119.188 158.371 171.395 1.00 33.36  ? 300 LEU B CG  1 
ATOM   4351 C  CD1 . LEU B 2 318 ? 118.551 159.680 171.782 1.00 36.03  ? 300 LEU B CD1 1 
ATOM   4352 C  CD2 . LEU B 2 318 ? 119.844 157.727 172.592 1.00 31.51  ? 300 LEU B CD2 1 
ATOM   4353 N  N   . LYS B 2 319 ? 116.684 154.677 169.490 1.00 31.50  ? 301 LYS B N   1 
ATOM   4354 C  CA  . LYS B 2 319 ? 115.391 154.060 169.248 1.00 30.87  ? 301 LYS B CA  1 
ATOM   4355 C  C   . LYS B 2 319 ? 115.479 152.652 168.686 1.00 32.39  ? 301 LYS B C   1 
ATOM   4356 O  O   . LYS B 2 319 ? 114.444 151.985 168.595 1.00 35.24  ? 301 LYS B O   1 
ATOM   4357 C  CB  . LYS B 2 319 ? 114.555 154.922 168.290 1.00 32.86  ? 301 LYS B CB  1 
ATOM   4358 C  CG  . LYS B 2 319 ? 114.294 156.331 168.783 1.00 31.12  ? 301 LYS B CG  1 
ATOM   4359 C  CD  . LYS B 2 319 ? 113.363 157.076 167.849 1.00 36.75  ? 301 LYS B CD  1 
ATOM   4360 C  CE  . LYS B 2 319 ? 111.946 156.549 167.940 1.00 38.77  ? 301 LYS B CE  1 
ATOM   4361 N  NZ  . LYS B 2 319 ? 111.257 157.030 169.160 1.00 38.69  ? 301 LYS B NZ  1 
ATOM   4362 N  N   . ALA B 2 320 ? 116.665 152.184 168.303 1.00 26.86  ? 302 ALA B N   1 
ATOM   4363 C  CA  . ALA B 2 320 ? 116.876 150.809 167.859 1.00 23.84  ? 302 ALA B CA  1 
ATOM   4364 C  C   . ALA B 2 320 ? 116.041 150.481 166.628 1.00 29.46  ? 302 ALA B C   1 
ATOM   4365 O  O   . ALA B 2 320 ? 115.482 149.390 166.510 1.00 37.13  ? 302 ALA B O   1 
ATOM   4366 C  CB  . ALA B 2 320 ? 116.590 149.814 168.982 1.00 26.70  ? 302 ALA B CB  1 
ATOM   4367 N  N   . ASP B 2 321 ? 115.960 151.430 165.702 1.00 27.07  ? 303 ASP B N   1 
ATOM   4368 C  CA  . ASP B 2 321 ? 115.240 151.254 164.451 1.00 20.62  ? 303 ASP B CA  1 
ATOM   4369 C  C   . ASP B 2 321 ? 116.183 151.539 163.297 1.00 17.86  ? 303 ASP B C   1 
ATOM   4370 O  O   . ASP B 2 321 ? 116.859 152.569 163.289 1.00 31.03  ? 303 ASP B O   1 
ATOM   4371 C  CB  . ASP B 2 321 ? 114.024 152.175 164.386 1.00 22.30  ? 303 ASP B CB  1 
ATOM   4372 C  CG  . ASP B 2 321 ? 112.763 151.508 164.900 1.00 35.65  ? 303 ASP B CG  1 
ATOM   4373 O  OD1 . ASP B 2 321 ? 112.387 150.450 164.353 1.00 38.35  ? 303 ASP B OD1 1 
ATOM   4374 O  OD2 . ASP B 2 321 ? 112.147 152.039 165.848 1.00 36.91  ? 303 ASP B OD2 1 
ATOM   4375 N  N   . ARG B 2 322 ? 116.229 150.630 162.331 1.00 16.13  ? 304 ARG B N   1 
ATOM   4376 C  CA  . ARG B 2 322 ? 117.100 150.810 161.182 1.00 17.98  ? 304 ARG B CA  1 
ATOM   4377 C  C   . ARG B 2 322 ? 116.719 152.067 160.419 1.00 29.66  ? 304 ARG B C   1 
ATOM   4378 O  O   . ARG B 2 322 ? 115.539 152.356 160.210 1.00 35.33  ? 304 ARG B O   1 
ATOM   4379 C  CB  . ARG B 2 322 ? 117.017 149.601 160.260 1.00 14.99  ? 304 ARG B CB  1 
ATOM   4380 C  CG  . ARG B 2 322 ? 118.340 149.163 159.708 1.00 20.20  ? 304 ARG B CG  1 
ATOM   4381 C  CD  . ARG B 2 322 ? 118.269 147.722 159.281 1.00 26.15  ? 304 ARG B CD  1 
ATOM   4382 N  NE  . ARG B 2 322 ? 117.753 147.576 157.928 1.00 28.80  ? 304 ARG B NE  1 
ATOM   4383 C  CZ  . ARG B 2 322 ? 117.319 146.435 157.411 1.00 33.83  ? 304 ARG B CZ  1 
ATOM   4384 N  NH1 . ARG B 2 322 ? 117.300 145.319 158.119 1.00 29.12  ? 304 ARG B NH1 1 
ATOM   4385 N  NH2 . ARG B 2 322 ? 116.891 146.414 156.153 1.00 32.53  ? 304 ARG B NH2 1 
ATOM   4386 N  N   . ALA B 2 323 ? 117.730 152.818 159.997 1.00 29.31  ? 305 ALA B N   1 
ATOM   4387 C  CA  . ALA B 2 323 ? 117.516 154.069 159.298 1.00 20.53  ? 305 ALA B CA  1 
ATOM   4388 C  C   . ALA B 2 323 ? 118.213 154.137 157.951 1.00 23.72  ? 305 ALA B C   1 
ATOM   4389 O  O   . ALA B 2 323 ? 118.095 155.156 157.269 1.00 42.78  ? 305 ALA B O   1 
ATOM   4390 C  CB  . ALA B 2 323 ? 117.973 155.246 160.168 1.00 20.01  ? 305 ALA B CB  1 
ATOM   4391 N  N   . GLY B 2 324 ? 118.934 153.104 157.543 1.00 12.74  ? 306 GLY B N   1 
ATOM   4392 C  CA  . GLY B 2 324 ? 119.597 153.152 156.257 1.00 14.37  ? 306 GLY B CA  1 
ATOM   4393 C  C   . GLY B 2 324 ? 120.464 151.938 156.043 1.00 14.05  ? 306 GLY B C   1 
ATOM   4394 O  O   . GLY B 2 324 ? 120.779 151.194 156.968 1.00 25.49  ? 306 GLY B O   1 
ATOM   4395 N  N   . VAL B 2 325 ? 120.870 151.768 154.789 1.00 14.12  ? 307 VAL B N   1 
ATOM   4396 C  CA  . VAL B 2 325 ? 121.661 150.630 154.344 1.00 12.53  ? 307 VAL B CA  1 
ATOM   4397 C  C   . VAL B 2 325 ? 122.786 151.145 153.460 1.00 19.97  ? 307 VAL B C   1 
ATOM   4398 O  O   . VAL B 2 325 ? 122.587 152.072 152.668 1.00 25.07  ? 307 VAL B O   1 
ATOM   4399 C  CB  . VAL B 2 325 ? 120.791 149.606 153.584 1.00 14.16  ? 307 VAL B CB  1 
ATOM   4400 C  CG1 . VAL B 2 325 ? 121.641 148.511 152.983 1.00 14.33  ? 307 VAL B CG1 1 
ATOM   4401 C  CG2 . VAL B 2 325 ? 119.745 149.012 154.502 1.00 20.34  ? 307 VAL B CG2 1 
ATOM   4402 N  N   . LEU B 2 326 ? 123.971 150.558 153.604 1.00 16.86  ? 308 LEU B N   1 
ATOM   4403 C  CA  . LEU B 2 326 ? 125.138 150.857 152.778 1.00 8.99   ? 308 LEU B CA  1 
ATOM   4404 C  C   . LEU B 2 326 ? 125.459 149.587 151.999 1.00 12.72  ? 308 LEU B C   1 
ATOM   4405 O  O   . LEU B 2 326 ? 126.159 148.703 152.498 1.00 12.78  ? 308 LEU B O   1 
ATOM   4406 C  CB  . LEU B 2 326 ? 126.323 151.300 153.621 1.00 8.46   ? 308 LEU B CB  1 
ATOM   4407 C  CG  . LEU B 2 326 ? 126.481 152.743 154.085 1.00 9.62   ? 308 LEU B CG  1 
ATOM   4408 C  CD1 . LEU B 2 326 ? 125.420 153.110 155.081 1.00 10.13  ? 308 LEU B CD1 1 
ATOM   4409 C  CD2 . LEU B 2 326 ? 127.842 152.907 154.704 1.00 9.44   ? 308 LEU B CD2 1 
ATOM   4410 N  N   . ALA B 2 327 ? 124.950 149.501 150.772 1.00 18.10  ? 309 ALA B N   1 
ATOM   4411 C  CA  . ALA B 2 327 ? 125.054 148.307 149.936 1.00 18.10  ? 309 ALA B CA  1 
ATOM   4412 C  C   . ALA B 2 327 ? 125.891 148.624 148.702 1.00 15.25  ? 309 ALA B C   1 
ATOM   4413 O  O   . ALA B 2 327 ? 125.369 149.125 147.707 1.00 20.08  ? 309 ALA B O   1 
ATOM   4414 C  CB  . ALA B 2 327 ? 123.676 147.809 149.549 1.00 13.18  ? 309 ALA B CB  1 
ATOM   4415 N  N   . GLY B 2 328 ? 127.190 148.343 148.767 1.00 19.56  ? 310 GLY B N   1 
ATOM   4416 C  CA  . GLY B 2 328 ? 128.057 148.572 147.630 1.00 14.31  ? 310 GLY B CA  1 
ATOM   4417 C  C   . GLY B 2 328 ? 129.181 147.576 147.434 1.00 18.20  ? 310 GLY B C   1 
ATOM   4418 O  O   . GLY B 2 328 ? 129.966 147.709 146.494 1.00 22.41  ? 310 GLY B O   1 
ATOM   4419 N  N   . HIS B 2 329 ? 129.276 146.572 148.298 1.00 17.29  ? 311 HIS B N   1 
ATOM   4420 C  CA  . HIS B 2 329 ? 130.390 145.635 148.285 1.00 19.00  ? 311 HIS B CA  1 
ATOM   4421 C  C   . HIS B 2 329 ? 129.927 144.270 147.797 1.00 16.59  ? 311 HIS B C   1 
ATOM   4422 O  O   . HIS B 2 329 ? 128.764 143.895 147.957 1.00 17.83  ? 311 HIS B O   1 
ATOM   4423 C  CB  . HIS B 2 329 ? 131.020 145.508 149.677 1.00 21.00  ? 311 HIS B CB  1 
ATOM   4424 C  CG  . HIS B 2 329 ? 131.825 146.701 150.094 1.00 19.87  ? 311 HIS B CG  1 
ATOM   4425 N  ND1 . HIS B 2 329 ? 133.084 146.961 149.600 1.00 18.07  ? 311 HIS B ND1 1 
ATOM   4426 C  CD2 . HIS B 2 329 ? 131.552 147.698 150.967 1.00 11.65  ? 311 HIS B CD2 1 
ATOM   4427 C  CE1 . HIS B 2 329 ? 133.550 148.066 150.147 1.00 6.19   ? 311 HIS B CE1 1 
ATOM   4428 N  NE2 . HIS B 2 329 ? 132.639 148.535 150.978 1.00 6.51   ? 311 HIS B NE2 1 
ATOM   4429 N  N   . ASP B 2 330 ? 130.848 143.533 147.185 1.00 15.80  ? 312 ASP B N   1 
ATOM   4430 C  CA  . ASP B 2 330 ? 130.547 142.229 146.612 1.00 18.72  ? 312 ASP B CA  1 
ATOM   4431 C  C   . ASP B 2 330 ? 131.073 141.069 147.446 1.00 26.93  ? 312 ASP B C   1 
ATOM   4432 O  O   . ASP B 2 330 ? 130.864 139.914 147.071 1.00 24.28  ? 312 ASP B O   1 
ATOM   4433 C  CB  . ASP B 2 330 ? 131.109 142.135 145.190 1.00 19.31  ? 312 ASP B CB  1 
ATOM   4434 C  CG  . ASP B 2 330 ? 130.204 142.787 144.158 1.00 31.92  ? 312 ASP B CG  1 
ATOM   4435 O  OD1 . ASP B 2 330 ? 129.009 142.429 144.096 1.00 29.85  ? 312 ASP B OD1 1 
ATOM   4436 O  OD2 . ASP B 2 330 ? 130.686 143.661 143.408 1.00 34.37  ? 312 ASP B OD2 1 
ATOM   4437 N  N   . ASN B 2 331 ? 131.750 141.342 148.559 1.00 22.99  ? 313 ASN B N   1 
ATOM   4438 C  CA  . ASN B 2 331 ? 132.177 140.307 149.486 1.00 9.35   ? 313 ASN B CA  1 
ATOM   4439 C  C   . ASN B 2 331 ? 132.005 140.829 150.905 1.00 17.54  ? 313 ASN B C   1 
ATOM   4440 O  O   . ASN B 2 331 ? 131.595 141.971 151.123 1.00 21.66  ? 313 ASN B O   1 
ATOM   4441 C  CB  . ASN B 2 331 ? 133.619 139.870 149.219 1.00 10.43  ? 313 ASN B CB  1 
ATOM   4442 C  CG  . ASN B 2 331 ? 133.839 138.395 149.481 1.00 18.47  ? 313 ASN B CG  1 
ATOM   4443 O  OD1 . ASN B 2 331 ? 133.184 137.800 150.328 1.00 20.45  ? 313 ASN B OD1 1 
ATOM   4444 N  ND2 . ASN B 2 331 ? 134.765 137.798 148.750 1.00 19.11  ? 313 ASN B ND2 1 
ATOM   4445 N  N   . ARG B 2 332 ? 132.322 139.969 151.871 1.00 20.54  ? 314 ARG B N   1 
ATOM   4446 C  CA  . ARG B 2 332 ? 132.081 140.252 153.280 1.00 9.65   ? 314 ARG B CA  1 
ATOM   4447 C  C   . ARG B 2 332 ? 132.780 141.534 153.714 1.00 7.02   ? 314 ARG B C   1 
ATOM   4448 O  O   . ARG B 2 332 ? 133.926 141.790 153.343 1.00 3.32   ? 314 ARG B O   1 
ATOM   4449 C  CB  . ARG B 2 332 ? 132.562 139.063 154.115 1.00 9.84   ? 314 ARG B CB  1 
ATOM   4450 C  CG  . ARG B 2 332 ? 132.804 139.347 155.572 1.00 9.69   ? 314 ARG B CG  1 
ATOM   4451 C  CD  . ARG B 2 332 ? 133.778 138.359 156.163 1.00 0.00   ? 314 ARG B CD  1 
ATOM   4452 N  NE  . ARG B 2 332 ? 133.366 137.933 157.492 1.00 10.16  ? 314 ARG B NE  1 
ATOM   4453 C  CZ  . ARG B 2 332 ? 133.946 136.967 158.191 1.00 16.45  ? 314 ARG B CZ  1 
ATOM   4454 N  NH1 . ARG B 2 332 ? 134.987 136.305 157.724 1.00 15.57  ? 314 ARG B NH1 1 
ATOM   4455 N  NH2 . ARG B 2 332 ? 133.467 136.659 159.390 1.00 11.92  ? 314 ARG B NH2 1 
ATOM   4456 N  N   . VAL B 2 333 ? 132.076 142.351 154.493 1.00 7.29   ? 315 VAL B N   1 
ATOM   4457 C  CA  . VAL B 2 333 ? 132.626 143.613 154.976 1.00 16.90  ? 315 VAL B CA  1 
ATOM   4458 C  C   . VAL B 2 333 ? 133.459 143.337 156.219 1.00 13.47  ? 315 VAL B C   1 
ATOM   4459 O  O   . VAL B 2 333 ? 132.957 142.800 157.209 1.00 17.05  ? 315 VAL B O   1 
ATOM   4460 C  CB  . VAL B 2 333 ? 131.513 144.628 155.273 1.00 11.18  ? 315 VAL B CB  1 
ATOM   4461 C  CG1 . VAL B 2 333 ? 132.063 146.037 155.268 1.00 1.64   ? 315 VAL B CG1 1 
ATOM   4462 C  CG2 . VAL B 2 333 ? 130.408 144.500 154.269 1.00 15.26  ? 315 VAL B CG2 1 
ATOM   4463 N  N   . SER B 2 334 ? 134.731 143.718 156.177 1.00 0.00   ? 316 SER B N   1 
ATOM   4464 C  CA  . SER B 2 334 ? 135.658 143.439 157.261 1.00 0.00   ? 316 SER B CA  1 
ATOM   4465 C  C   . SER B 2 334 ? 135.911 144.633 158.172 1.00 15.64  ? 316 SER B C   1 
ATOM   4466 O  O   . SER B 2 334 ? 136.021 144.457 159.385 1.00 22.39  ? 316 SER B O   1 
ATOM   4467 C  CB  . SER B 2 334 ? 136.986 142.933 156.696 1.00 9.24   ? 316 SER B CB  1 
ATOM   4468 O  OG  . SER B 2 334 ? 137.301 143.551 155.469 1.00 0.20   ? 316 SER B OG  1 
ATOM   4469 N  N   . CYS B 2 335 ? 136.000 145.844 157.630 1.00 19.08  ? 317 CYS B N   1 
ATOM   4470 C  CA  . CYS B 2 335 ? 136.351 147.023 158.406 1.00 5.46   ? 317 CYS B CA  1 
ATOM   4471 C  C   . CYS B 2 335 ? 135.356 148.148 158.144 1.00 11.50  ? 317 CYS B C   1 
ATOM   4472 O  O   . CYS B 2 335 ? 134.577 148.114 157.191 1.00 19.13  ? 317 CYS B O   1 
ATOM   4473 C  CB  . CYS B 2 335 ? 137.782 147.473 158.102 1.00 0.00   ? 317 CYS B CB  1 
ATOM   4474 S  SG  . CYS B 2 335 ? 138.136 147.773 156.368 1.00 29.10  ? 317 CYS B SG  1 
ATOM   4475 N  N   . LEU B 2 336 ? 135.381 149.147 159.025 1.00 16.82  ? 318 LEU B N   1 
ATOM   4476 C  CA  . LEU B 2 336 ? 134.399 150.224 159.037 1.00 4.81   ? 318 LEU B CA  1 
ATOM   4477 C  C   . LEU B 2 336 ? 134.861 151.340 159.968 1.00 11.18  ? 318 LEU B C   1 
ATOM   4478 O  O   . LEU B 2 336 ? 135.167 151.074 161.131 1.00 25.36  ? 318 LEU B O   1 
ATOM   4479 C  CB  . LEU B 2 336 ? 133.046 149.671 159.486 1.00 8.90   ? 318 LEU B CB  1 
ATOM   4480 C  CG  . LEU B 2 336 ? 131.762 150.470 159.336 1.00 12.41  ? 318 LEU B CG  1 
ATOM   4481 C  CD1 . LEU B 2 336 ? 130.720 149.594 158.725 1.00 12.18  ? 318 LEU B CD1 1 
ATOM   4482 C  CD2 . LEU B 2 336 ? 131.299 150.940 160.668 1.00 0.00   ? 318 LEU B CD2 1 
ATOM   4483 N  N   . GLY B 2 337 ? 134.897 152.582 159.500 1.00 0.00   ? 319 GLY B N   1 
ATOM   4484 C  CA  . GLY B 2 337 ? 135.386 153.674 160.326 1.00 0.00   ? 319 GLY B CA  1 
ATOM   4485 C  C   . GLY B 2 337 ? 134.767 155.003 159.964 1.00 6.58   ? 319 GLY B C   1 
ATOM   4486 O  O   . GLY B 2 337 ? 134.380 155.234 158.819 1.00 23.41  ? 319 GLY B O   1 
ATOM   4487 N  N   . VAL B 2 338 ? 134.691 155.891 160.954 1.00 5.38   ? 320 VAL B N   1 
ATOM   4488 C  CA  . VAL B 2 338 ? 134.109 157.222 160.814 1.00 6.56   ? 320 VAL B CA  1 
ATOM   4489 C  C   . VAL B 2 338 ? 135.177 158.246 161.167 1.00 10.21  ? 320 VAL B C   1 
ATOM   4490 O  O   . VAL B 2 338 ? 135.962 158.033 162.095 1.00 15.85  ? 320 VAL B O   1 
ATOM   4491 C  CB  . VAL B 2 338 ? 132.861 157.403 161.710 1.00 8.14   ? 320 VAL B CB  1 
ATOM   4492 C  CG1 . VAL B 2 338 ? 132.233 158.766 161.501 1.00 11.03  ? 320 VAL B CG1 1 
ATOM   4493 C  CG2 . VAL B 2 338 ? 131.837 156.323 161.445 1.00 8.55   ? 320 VAL B CG2 1 
ATOM   4494 N  N   . THR B 2 339 ? 135.210 159.355 160.428 1.00 17.73  ? 321 THR B N   1 
ATOM   4495 C  CA  . THR B 2 339 ? 136.248 160.361 160.615 1.00 16.75  ? 321 THR B CA  1 
ATOM   4496 C  C   . THR B 2 339 ? 136.058 161.117 161.926 1.00 18.18  ? 321 THR B C   1 
ATOM   4497 O  O   . THR B 2 339 ? 134.993 161.096 162.545 1.00 25.93  ? 321 THR B O   1 
ATOM   4498 C  CB  . THR B 2 339 ? 136.266 161.361 159.460 1.00 15.18  ? 321 THR B CB  1 
ATOM   4499 O  OG1 . THR B 2 339 ? 134.972 161.944 159.312 1.00 23.80  ? 321 THR B OG1 1 
ATOM   4500 C  CG2 . THR B 2 339 ? 136.647 160.696 158.174 1.00 17.63  ? 321 THR B CG2 1 
ATOM   4501 N  N   . ASP B 2 340 ? 137.124 161.803 162.346 1.00 24.60  ? 322 ASP B N   1 
ATOM   4502 C  CA  . ASP B 2 340 ? 137.091 162.559 163.590 1.00 22.85  ? 322 ASP B CA  1 
ATOM   4503 C  C   . ASP B 2 340 ? 136.292 163.848 163.476 1.00 20.90  ? 322 ASP B C   1 
ATOM   4504 O  O   . ASP B 2 340 ? 135.874 164.387 164.503 1.00 30.31  ? 322 ASP B O   1 
ATOM   4505 C  CB  . ASP B 2 340 ? 138.509 162.878 164.057 1.00 21.82  ? 322 ASP B CB  1 
ATOM   4506 C  CG  . ASP B 2 340 ? 139.244 161.657 164.558 1.00 30.26  ? 322 ASP B CG  1 
ATOM   4507 O  OD1 . ASP B 2 340 ? 138.587 160.626 164.813 1.00 28.43  ? 322 ASP B OD1 1 
ATOM   4508 O  OD2 . ASP B 2 340 ? 140.483 161.730 164.690 1.00 28.76  ? 322 ASP B OD2 1 
ATOM   4509 N  N   . ASP B 2 341 ? 136.088 164.369 162.271 1.00 14.76  ? 323 ASP B N   1 
ATOM   4510 C  CA  . ASP B 2 341 ? 135.146 165.462 162.075 1.00 21.91  ? 323 ASP B CA  1 
ATOM   4511 C  C   . ASP B 2 341 ? 133.768 164.968 161.660 1.00 25.12  ? 323 ASP B C   1 
ATOM   4512 O  O   . ASP B 2 341 ? 132.856 165.781 161.500 1.00 30.98  ? 323 ASP B O   1 
ATOM   4513 C  CB  . ASP B 2 341 ? 135.680 166.465 161.046 1.00 20.72  ? 323 ASP B CB  1 
ATOM   4514 C  CG  . ASP B 2 341 ? 136.000 165.830 159.716 1.00 31.64  ? 323 ASP B CG  1 
ATOM   4515 O  OD1 . ASP B 2 341 ? 136.120 164.595 159.658 1.00 31.32  ? 323 ASP B OD1 1 
ATOM   4516 O  OD2 . ASP B 2 341 ? 136.134 166.570 158.722 1.00 34.15  ? 323 ASP B OD2 1 
ATOM   4517 N  N   . GLY B 2 342 ? 133.598 163.659 161.502 1.00 21.94  ? 324 GLY B N   1 
ATOM   4518 C  CA  . GLY B 2 342 ? 132.292 163.076 161.283 1.00 24.45  ? 324 GLY B CA  1 
ATOM   4519 C  C   . GLY B 2 342 ? 131.721 163.274 159.907 1.00 23.91  ? 324 GLY B C   1 
ATOM   4520 O  O   . GLY B 2 342 ? 130.505 163.205 159.744 1.00 33.19  ? 324 GLY B O   1 
ATOM   4521 N  N   . MET B 2 343 ? 132.559 163.506 158.904 1.00 22.41  ? 325 MET B N   1 
ATOM   4522 C  CA  . MET B 2 343 ? 132.094 163.932 157.596 1.00 23.53  ? 325 MET B CA  1 
ATOM   4523 C  C   . MET B 2 343 ? 132.192 162.840 156.540 1.00 25.50  ? 325 MET B C   1 
ATOM   4524 O  O   . MET B 2 343 ? 131.750 163.053 155.410 1.00 32.78  ? 325 MET B O   1 
ATOM   4525 C  CB  . MET B 2 343 ? 132.879 165.179 157.166 1.00 26.14  ? 325 MET B CB  1 
ATOM   4526 C  CG  . MET B 2 343 ? 132.349 165.922 155.957 1.00 30.10  ? 325 MET B CG  1 
ATOM   4527 S  SD  . MET B 2 343 ? 131.524 167.447 156.428 1.00 46.69  ? 325 MET B SD  1 
ATOM   4528 C  CE  . MET B 2 343 ? 132.828 168.262 157.331 1.00 26.97  ? 325 MET B CE  1 
ATOM   4529 N  N   . ALA B 2 344 ? 132.729 161.671 156.874 1.00 18.92  ? 326 ALA B N   1 
ATOM   4530 C  CA  . ALA B 2 344 ? 132.791 160.581 155.913 1.00 10.05  ? 326 ALA B CA  1 
ATOM   4531 C  C   . ALA B 2 344 ? 132.895 159.258 156.652 1.00 17.78  ? 326 ALA B C   1 
ATOM   4532 O  O   . ALA B 2 344 ? 133.306 159.204 157.812 1.00 24.46  ? 326 ALA B O   1 
ATOM   4533 C  CB  . ALA B 2 344 ? 133.968 160.741 154.953 1.00 16.29  ? 326 ALA B CB  1 
ATOM   4534 N  N   . VAL B 2 345 ? 132.521 158.189 155.954 1.00 18.57  ? 327 VAL B N   1 
ATOM   4535 C  CA  . VAL B 2 345 ? 132.616 156.825 156.462 1.00 8.84   ? 327 VAL B CA  1 
ATOM   4536 C  C   . VAL B 2 345 ? 133.398 156.004 155.451 1.00 7.63   ? 327 VAL B C   1 
ATOM   4537 O  O   . VAL B 2 345 ? 133.116 156.067 154.255 1.00 19.14  ? 327 VAL B O   1 
ATOM   4538 C  CB  . VAL B 2 345 ? 131.226 156.203 156.695 1.00 12.06  ? 327 VAL B CB  1 
ATOM   4539 C  CG1 . VAL B 2 345 ? 131.346 154.856 157.365 1.00 10.68  ? 327 VAL B CG1 1 
ATOM   4540 C  CG2 . VAL B 2 345 ? 130.378 157.119 157.524 1.00 17.52  ? 327 VAL B CG2 1 
ATOM   4541 N  N   . ALA B 2 346 ? 134.373 155.236 155.915 1.00 6.44   ? 328 ALA B N   1 
ATOM   4542 C  CA  . ALA B 2 346 ? 135.130 154.349 155.046 1.00 1.49   ? 328 ALA B CA  1 
ATOM   4543 C  C   . ALA B 2 346 ? 134.825 152.908 155.413 1.00 11.50  ? 328 ALA B C   1 
ATOM   4544 O  O   . ALA B 2 346 ? 134.816 152.557 156.594 1.00 20.87  ? 328 ALA B O   1 
ATOM   4545 C  CB  . ALA B 2 346 ? 136.629 154.616 155.152 1.00 0.61   ? 328 ALA B CB  1 
ATOM   4546 N  N   . THR B 2 347 ? 134.543 152.085 154.407 1.00 11.79  ? 329 THR B N   1 
ATOM   4547 C  CA  . THR B 2 347 ? 134.334 150.657 154.611 1.00 10.61  ? 329 THR B CA  1 
ATOM   4548 C  C   . THR B 2 347 ? 135.199 149.879 153.637 1.00 8.93   ? 329 THR B C   1 
ATOM   4549 O  O   . THR B 2 347 ? 135.165 150.137 152.432 1.00 17.01  ? 329 THR B O   1 
ATOM   4550 C  CB  . THR B 2 347 ? 132.864 150.243 154.431 1.00 12.82  ? 329 THR B CB  1 
ATOM   4551 O  OG1 . THR B 2 347 ? 132.547 150.179 153.039 1.00 15.51  ? 329 THR B OG1 1 
ATOM   4552 C  CG2 . THR B 2 347 ? 131.922 151.204 155.126 1.00 15.82  ? 329 THR B CG2 1 
ATOM   4553 N  N   . GLY B 2 348 ? 135.980 148.943 154.163 1.00 10.76  ? 330 GLY B N   1 
ATOM   4554 C  CA  . GLY B 2 348 ? 136.696 147.985 153.353 1.00 9.42   ? 330 GLY B CA  1 
ATOM   4555 C  C   . GLY B 2 348 ? 135.965 146.658 153.321 1.00 8.25   ? 330 GLY B C   1 
ATOM   4556 O  O   . GLY B 2 348 ? 134.999 146.435 154.037 1.00 5.25   ? 330 GLY B O   1 
ATOM   4557 N  N   . SER B 2 349 ? 136.439 145.766 152.461 1.00 13.80  ? 331 SER B N   1 
ATOM   4558 C  CA  . SER B 2 349 ? 135.738 144.506 152.273 1.00 6.15   ? 331 SER B CA  1 
ATOM   4559 C  C   . SER B 2 349 ? 136.685 143.473 151.692 1.00 8.48   ? 331 SER B C   1 
ATOM   4560 O  O   . SER B 2 349 ? 137.803 143.779 151.282 1.00 17.02  ? 331 SER B O   1 
ATOM   4561 C  CB  . SER B 2 349 ? 134.515 144.679 151.377 1.00 11.13  ? 331 SER B CB  1 
ATOM   4562 O  OG  . SER B 2 349 ? 133.781 143.477 151.277 1.00 21.11  ? 331 SER B OG  1 
ATOM   4563 N  N   . TRP B 2 350 ? 136.207 142.237 151.664 1.00 12.15  ? 332 TRP B N   1 
ATOM   4564 C  CA  . TRP B 2 350 ? 136.977 141.094 151.204 1.00 13.13  ? 332 TRP B CA  1 
ATOM   4565 C  C   . TRP B 2 350 ? 137.123 141.046 149.689 1.00 22.33  ? 332 TRP B C   1 
ATOM   4566 O  O   . TRP B 2 350 ? 137.821 140.164 149.180 1.00 24.82  ? 332 TRP B O   1 
ATOM   4567 C  CB  . TRP B 2 350 ? 136.334 139.803 151.711 1.00 6.70   ? 332 TRP B CB  1 
ATOM   4568 C  CG  . TRP B 2 350 ? 136.814 139.373 153.063 1.00 10.52  ? 332 TRP B CG  1 
ATOM   4569 C  CD1 . TRP B 2 350 ? 137.433 140.142 153.994 1.00 12.61  ? 332 TRP B CD1 1 
ATOM   4570 C  CD2 . TRP B 2 350 ? 136.714 138.064 153.629 1.00 16.42  ? 332 TRP B CD2 1 
ATOM   4571 N  NE1 . TRP B 2 350 ? 137.726 139.400 155.106 1.00 11.53  ? 332 TRP B NE1 1 
ATOM   4572 C  CE2 . TRP B 2 350 ? 137.295 138.117 154.906 1.00 19.79  ? 332 TRP B CE2 1 
ATOM   4573 C  CE3 . TRP B 2 350 ? 136.190 136.851 153.179 1.00 14.85  ? 332 TRP B CE3 1 
ATOM   4574 C  CZ2 . TRP B 2 350 ? 137.369 137.003 155.739 1.00 11.50  ? 332 TRP B CZ2 1 
ATOM   4575 C  CZ3 . TRP B 2 350 ? 136.265 135.750 154.007 1.00 13.69  ? 332 TRP B CZ3 1 
ATOM   4576 C  CH2 . TRP B 2 350 ? 136.850 135.834 155.271 1.00 6.40   ? 332 TRP B CH2 1 
ATOM   4577 N  N   . ASP B 2 351 ? 136.478 141.954 148.959 1.00 13.76  ? 333 ASP B N   1 
ATOM   4578 C  CA  . ASP B 2 351 ? 136.661 142.089 147.522 1.00 7.98   ? 333 ASP B CA  1 
ATOM   4579 C  C   . ASP B 2 351 ? 137.771 143.072 147.165 1.00 12.57  ? 333 ASP B C   1 
ATOM   4580 O  O   . ASP B 2 351 ? 137.964 143.365 145.982 1.00 16.51  ? 333 ASP B O   1 
ATOM   4581 C  CB  . ASP B 2 351 ? 135.347 142.504 146.862 1.00 14.17  ? 333 ASP B CB  1 
ATOM   4582 C  CG  . ASP B 2 351 ? 134.844 143.830 147.353 1.00 23.13  ? 333 ASP B CG  1 
ATOM   4583 O  OD1 . ASP B 2 351 ? 135.308 144.279 148.409 1.00 24.24  ? 333 ASP B OD1 1 
ATOM   4584 O  OD2 . ASP B 2 351 ? 133.977 144.430 146.690 1.00 28.12  ? 333 ASP B OD2 1 
ATOM   4585 N  N   . SER B 2 352 ? 138.487 143.587 148.168 1.00 13.16  ? 334 SER B N   1 
ATOM   4586 C  CA  . SER B 2 352 ? 139.724 144.357 148.021 1.00 10.85  ? 334 SER B CA  1 
ATOM   4587 C  C   . SER B 2 352 ? 139.494 145.785 147.541 1.00 17.78  ? 334 SER B C   1 
ATOM   4588 O  O   . SER B 2 352 ? 140.370 146.376 146.909 1.00 19.43  ? 334 SER B O   1 
ATOM   4589 C  CB  . SER B 2 352 ? 140.718 143.650 147.101 1.00 7.18   ? 334 SER B CB  1 
ATOM   4590 O  OG  . SER B 2 352 ? 140.265 143.650 145.764 1.00 24.92  ? 334 SER B OG  1 
ATOM   4591 N  N   . PHE B 2 353 ? 138.346 146.376 147.859 1.00 8.94   ? 335 PHE B N   1 
ATOM   4592 C  CA  . PHE B 2 353 ? 138.079 147.767 147.525 1.00 15.68  ? 335 PHE B CA  1 
ATOM   4593 C  C   . PHE B 2 353 ? 137.644 148.508 148.773 1.00 12.14  ? 335 PHE B C   1 
ATOM   4594 O  O   . PHE B 2 353 ? 136.875 147.975 149.576 1.00 9.96   ? 335 PHE B O   1 
ATOM   4595 C  CB  . PHE B 2 353 ? 136.992 147.900 146.450 1.00 20.02  ? 335 PHE B CB  1 
ATOM   4596 C  CG  . PHE B 2 353 ? 137.352 147.264 145.145 1.00 18.61  ? 335 PHE B CG  1 
ATOM   4597 C  CD1 . PHE B 2 353 ? 138.550 147.555 144.530 1.00 14.22  ? 335 PHE B CD1 1 
ATOM   4598 C  CD2 . PHE B 2 353 ? 136.497 146.366 144.541 1.00 15.59  ? 335 PHE B CD2 1 
ATOM   4599 C  CE1 . PHE B 2 353 ? 138.888 146.967 143.345 1.00 10.58  ? 335 PHE B CE1 1 
ATOM   4600 C  CE2 . PHE B 2 353 ? 136.833 145.777 143.357 1.00 18.01  ? 335 PHE B CE2 1 
ATOM   4601 C  CZ  . PHE B 2 353 ? 138.029 146.079 142.757 1.00 19.70  ? 335 PHE B CZ  1 
ATOM   4602 N  N   . LEU B 2 354 ? 138.125 149.737 148.936 1.00 13.55  ? 336 LEU B N   1 
ATOM   4603 C  CA  . LEU B 2 354 ? 137.627 150.594 150.002 1.00 9.66   ? 336 LEU B CA  1 
ATOM   4604 C  C   . LEU B 2 354 ? 136.667 151.615 149.418 1.00 8.92   ? 336 LEU B C   1 
ATOM   4605 O  O   . LEU B 2 354 ? 136.856 152.079 148.297 1.00 19.19  ? 336 LEU B O   1 
ATOM   4606 C  CB  . LEU B 2 354 ? 138.756 151.312 150.737 1.00 12.26  ? 336 LEU B CB  1 
ATOM   4607 C  CG  . LEU B 2 354 ? 139.756 150.492 151.537 1.00 11.85  ? 336 LEU B CG  1 
ATOM   4608 C  CD1 . LEU B 2 354 ? 141.100 150.534 150.867 1.00 17.65  ? 336 LEU B CD1 1 
ATOM   4609 C  CD2 . LEU B 2 354 ? 139.840 151.035 152.943 1.00 9.99   ? 336 LEU B CD2 1 
ATOM   4610 N  N   . LYS B 2 355 ? 135.630 151.954 150.169 1.00 8.03   ? 337 LYS B N   1 
ATOM   4611 C  CA  . LYS B 2 355 ? 134.618 152.879 149.688 1.00 9.33   ? 337 LYS B CA  1 
ATOM   4612 C  C   . LYS B 2 355 ? 134.352 153.942 150.736 1.00 16.53  ? 337 LYS B C   1 
ATOM   4613 O  O   . LYS B 2 355 ? 134.291 153.642 151.930 1.00 19.55  ? 337 LYS B O   1 
ATOM   4614 C  CB  . LYS B 2 355 ? 133.331 152.150 149.345 1.00 6.27   ? 337 LYS B CB  1 
ATOM   4615 C  CG  . LYS B 2 355 ? 133.489 151.199 148.199 1.00 8.00   ? 337 LYS B CG  1 
ATOM   4616 C  CD  . LYS B 2 355 ? 132.169 150.730 147.674 1.00 10.44  ? 337 LYS B CD  1 
ATOM   4617 C  CE  . LYS B 2 355 ? 132.383 149.895 146.441 1.00 13.67  ? 337 LYS B CE  1 
ATOM   4618 N  NZ  . LYS B 2 355 ? 131.094 149.569 145.799 1.00 20.13  ? 337 LYS B NZ  1 
ATOM   4619 N  N   . ILE B 2 356 ? 134.182 155.182 150.284 1.00 10.91  ? 338 ILE B N   1 
ATOM   4620 C  CA  . ILE B 2 356 ? 133.959 156.317 151.169 1.00 10.80  ? 338 ILE B CA  1 
ATOM   4621 C  C   . ILE B 2 356 ? 132.581 156.893 150.890 1.00 12.23  ? 338 ILE B C   1 
ATOM   4622 O  O   . ILE B 2 356 ? 132.264 157.228 149.747 1.00 21.85  ? 338 ILE B O   1 
ATOM   4623 C  CB  . ILE B 2 356 ? 135.052 157.381 151.001 1.00 11.71  ? 338 ILE B CB  1 
ATOM   4624 C  CG1 . ILE B 2 356 ? 136.411 156.757 151.298 1.00 7.38   ? 338 ILE B CG1 1 
ATOM   4625 C  CG2 . ILE B 2 356 ? 134.785 158.565 151.905 1.00 12.88  ? 338 ILE B CG2 1 
ATOM   4626 C  CD1 . ILE B 2 356 ? 137.513 157.731 151.343 1.00 16.25  ? 338 ILE B CD1 1 
ATOM   4627 N  N   . TRP B 2 357 ? 131.773 157.009 151.938 1.00 16.72  ? 339 TRP B N   1 
ATOM   4628 C  CA  . TRP B 2 357 ? 130.371 157.384 151.864 1.00 13.06  ? 339 TRP B CA  1 
ATOM   4629 C  C   . TRP B 2 357 ? 130.146 158.675 152.632 1.00 16.74  ? 339 TRP B C   1 
ATOM   4630 O  O   . TRP B 2 357 ? 130.804 158.938 153.643 1.00 24.72  ? 339 TRP B O   1 
ATOM   4631 C  CB  . TRP B 2 357 ? 129.460 156.290 152.436 1.00 5.74   ? 339 TRP B CB  1 
ATOM   4632 C  CG  . TRP B 2 357 ? 129.844 154.897 152.055 1.00 9.33   ? 339 TRP B CG  1 
ATOM   4633 C  CD1 . TRP B 2 357 ? 130.950 154.213 152.454 1.00 13.22  ? 339 TRP B CD1 1 
ATOM   4634 C  CD2 . TRP B 2 357 ? 129.111 154.011 151.209 1.00 16.89  ? 339 TRP B CD2 1 
ATOM   4635 N  NE1 . TRP B 2 357 ? 130.961 152.963 151.901 1.00 14.40  ? 339 TRP B NE1 1 
ATOM   4636 C  CE2 . TRP B 2 357 ? 129.840 152.812 151.132 1.00 14.64  ? 339 TRP B CE2 1 
ATOM   4637 C  CE3 . TRP B 2 357 ? 127.910 154.115 150.505 1.00 12.78  ? 339 TRP B CE3 1 
ATOM   4638 C  CZ2 . TRP B 2 357 ? 129.410 151.729 150.383 1.00 8.48   ? 339 TRP B CZ2 1 
ATOM   4639 C  CZ3 . TRP B 2 357 ? 127.486 153.040 149.762 1.00 16.34  ? 339 TRP B CZ3 1 
ATOM   4640 C  CH2 . TRP B 2 357 ? 128.233 151.862 149.705 1.00 19.09  ? 339 TRP B CH2 1 
ATOM   4641 N  N   . ASN B 2 358 ? 129.200 159.468 152.150 1.00 20.41  ? 340 ASN B N   1 
ATOM   4642 C  CA  . ASN B 2 358 ? 128.956 160.790 152.697 1.00 24.56  ? 340 ASN B CA  1 
ATOM   4643 C  C   . ASN B 2 358 ? 127.472 161.134 152.674 1.00 28.37  ? 340 ASN B C   1 
ATOM   4644 O  O   . ASN B 2 358 ? 126.726 160.640 151.840 1.00 34.83  ? 340 ASN B O   1 
ATOM   4645 C  CB  . ASN B 2 358 ? 129.752 161.825 151.914 1.00 19.86  ? 340 ASN B CB  1 
ATOM   4646 C  CG  . ASN B 2 358 ? 129.781 163.167 152.589 1.00 25.65  ? 340 ASN B CG  1 
ATOM   4647 O  OD1 . ASN B 2 358 ? 129.739 163.253 153.811 1.00 30.07  ? 340 ASN B OD1 1 
ATOM   4648 N  ND2 . ASN B 2 358 ? 129.859 164.226 151.799 1.00 29.62  ? 340 ASN B ND2 1 
ATOM   4649 N  N   . THR C 3 6   ? 145.081 121.764 193.179 1.00 106.85 ? 6   THR G N   1 
ATOM   4650 C  CA  . THR C 3 6   ? 145.894 122.940 192.893 1.00 108.78 ? 6   THR G CA  1 
ATOM   4651 C  C   . THR C 3 6   ? 145.857 123.277 191.409 1.00 108.72 ? 6   THR G C   1 
ATOM   4652 O  O   . THR C 3 6   ? 146.075 124.424 191.016 1.00 107.34 ? 6   THR G O   1 
ATOM   4653 C  CB  . THR C 3 6   ? 147.358 122.737 193.326 1.00 108.95 ? 6   THR G CB  1 
ATOM   4654 O  OG1 . THR C 3 6   ? 147.936 121.661 192.576 1.00 109.00 ? 6   THR G OG1 1 
ATOM   4655 C  CG2 . THR C 3 6   ? 147.437 122.414 194.811 1.00 107.63 ? 6   THR G CG2 1 
ATOM   4656 N  N   . ALA C 3 7   ? 145.583 122.262 190.587 1.00 109.63 ? 7   ALA G N   1 
ATOM   4657 C  CA  . ALA C 3 7   ? 145.550 122.462 189.142 1.00 109.09 ? 7   ALA G CA  1 
ATOM   4658 C  C   . ALA C 3 7   ? 144.420 123.398 188.733 1.00 109.05 ? 7   ALA G C   1 
ATOM   4659 O  O   . ALA C 3 7   ? 144.593 124.235 187.840 1.00 107.85 ? 7   ALA G O   1 
ATOM   4660 C  CB  . ALA C 3 7   ? 145.418 121.117 188.430 1.00 107.54 ? 7   ALA G CB  1 
ATOM   4661 N  N   . SER C 3 8   ? 143.258 123.274 189.370 1.00 106.59 ? 8   SER G N   1 
ATOM   4662 C  CA  . SER C 3 8   ? 142.086 124.053 188.992 1.00 105.69 ? 8   SER G CA  1 
ATOM   4663 C  C   . SER C 3 8   ? 141.397 124.625 190.222 1.00 105.73 ? 8   SER G C   1 
ATOM   4664 O  O   . SER C 3 8   ? 140.168 124.741 190.268 1.00 106.23 ? 8   SER G O   1 
ATOM   4665 C  CB  . SER C 3 8   ? 141.112 123.213 188.168 1.00 105.33 ? 8   SER G CB  1 
ATOM   4666 O  OG  . SER C 3 8   ? 141.014 121.898 188.685 1.00 104.45 ? 8   SER G OG  1 
ATOM   4667 N  N   . ILE C 3 9   ? 142.175 124.992 191.239 1.00 105.46 ? 9   ILE G N   1 
ATOM   4668 C  CA  . ILE C 3 9   ? 141.636 125.695 192.390 1.00 106.50 ? 9   ILE G CA  1 
ATOM   4669 C  C   . ILE C 3 9   ? 142.164 127.123 192.500 1.00 106.92 ? 9   ILE G C   1 
ATOM   4670 O  O   . ILE C 3 9   ? 141.492 127.971 193.098 1.00 105.92 ? 9   ILE G O   1 
ATOM   4671 C  CB  . ILE C 3 9   ? 141.895 124.917 193.698 1.00 106.21 ? 9   ILE G CB  1 
ATOM   4672 C  CG1 . ILE C 3 9   ? 143.311 125.182 194.214 1.00 106.20 ? 9   ILE G CG1 1 
ATOM   4673 C  CG2 . ILE C 3 9   ? 141.653 123.432 193.491 1.00 106.20 ? 9   ILE G CG2 1 
ATOM   4674 C  CD1 . ILE C 3 9   ? 143.464 124.965 195.701 1.00 105.76 ? 9   ILE G CD1 1 
ATOM   4675 N  N   . ALA C 3 10  ? 143.343 127.415 191.948 1.00 108.11 ? 10  ALA G N   1 
ATOM   4676 C  CA  . ALA C 3 10  ? 143.805 128.797 191.907 1.00 107.52 ? 10  ALA G CA  1 
ATOM   4677 C  C   . ALA C 3 10  ? 142.904 129.642 191.018 1.00 106.52 ? 10  ALA G C   1 
ATOM   4678 O  O   . ALA C 3 10  ? 142.630 130.808 191.326 1.00 106.46 ? 10  ALA G O   1 
ATOM   4679 C  CB  . ALA C 3 10  ? 145.252 128.855 191.422 1.00 106.80 ? 10  ALA G CB  1 
ATOM   4680 N  N   . GLN C 3 11  ? 142.432 129.064 189.913 1.00 103.24 ? 11  GLN G N   1 
ATOM   4681 C  CA  . GLN C 3 11  ? 141.489 129.768 189.054 1.00 103.67 ? 11  GLN G CA  1 
ATOM   4682 C  C   . GLN C 3 11  ? 140.192 130.068 189.796 1.00 105.63 ? 11  GLN G C   1 
ATOM   4683 O  O   . GLN C 3 11  ? 139.621 131.153 189.646 1.00 104.98 ? 11  GLN G O   1 
ATOM   4684 C  CB  . GLN C 3 11  ? 141.216 128.945 187.797 1.00 101.73 ? 11  GLN G CB  1 
ATOM   4685 C  CG  . GLN C 3 11  ? 142.401 128.109 187.343 1.00 103.48 ? 11  GLN G CG  1 
ATOM   4686 C  CD  . GLN C 3 11  ? 143.580 128.953 186.896 1.00 105.15 ? 11  GLN G CD  1 
ATOM   4687 O  OE1 . GLN C 3 11  ? 144.569 129.090 187.616 1.00 105.82 ? 11  GLN G OE1 1 
ATOM   4688 N  NE2 . GLN C 3 11  ? 143.483 129.519 185.698 1.00 104.37 ? 11  GLN G NE2 1 
ATOM   4689 N  N   . ALA C 3 12  ? 139.712 129.119 190.603 1.00 107.30 ? 12  ALA G N   1 
ATOM   4690 C  CA  . ALA C 3 12  ? 138.504 129.359 191.385 1.00 105.65 ? 12  ALA G CA  1 
ATOM   4691 C  C   . ALA C 3 12  ? 138.717 130.456 192.424 1.00 104.84 ? 12  ALA G C   1 
ATOM   4692 O  O   . ALA C 3 12  ? 137.835 131.297 192.634 1.00 104.97 ? 12  ALA G O   1 
ATOM   4693 C  CB  . ALA C 3 12  ? 138.044 128.064 192.050 1.00 104.48 ? 12  ALA G CB  1 
ATOM   4694 N  N   . ARG C 3 13  ? 139.877 130.466 193.085 1.00 100.53 ? 13  ARG G N   1 
ATOM   4695 C  CA  . ARG C 3 13  ? 140.166 131.528 194.045 1.00 102.35 ? 13  ARG G CA  1 
ATOM   4696 C  C   . ARG C 3 13  ? 140.214 132.889 193.361 1.00 102.65 ? 13  ARG G C   1 
ATOM   4697 O  O   . ARG C 3 13  ? 139.671 133.874 193.877 1.00 102.06 ? 13  ARG G O   1 
ATOM   4698 C  CB  . ARG C 3 13  ? 141.488 131.249 194.761 1.00 102.83 ? 13  ARG G CB  1 
ATOM   4699 C  CG  . ARG C 3 13  ? 141.427 130.130 195.784 1.00 103.08 ? 13  ARG G CG  1 
ATOM   4700 C  CD  . ARG C 3 13  ? 140.994 130.639 197.149 1.00 102.47 ? 13  ARG G CD  1 
ATOM   4701 N  NE  . ARG C 3 13  ? 140.115 129.688 197.818 1.00 103.21 ? 13  ARG G NE  1 
ATOM   4702 C  CZ  . ARG C 3 13  ? 139.721 129.783 199.081 1.00 103.80 ? 13  ARG G CZ  1 
ATOM   4703 N  NH1 . ARG C 3 13  ? 140.119 130.779 199.856 1.00 102.16 ? 13  ARG G NH1 1 
ATOM   4704 N  NH2 . ARG C 3 13  ? 138.907 128.857 199.578 1.00 103.74 ? 13  ARG G NH2 1 
ATOM   4705 N  N   . LYS C 3 14  ? 140.862 132.960 192.195 1.00 96.92  ? 14  LYS G N   1 
ATOM   4706 C  CA  . LYS C 3 14  ? 140.934 134.221 191.466 1.00 96.42  ? 14  LYS G CA  1 
ATOM   4707 C  C   . LYS C 3 14  ? 139.555 134.670 191.005 1.00 97.22  ? 14  LYS G C   1 
ATOM   4708 O  O   . LYS C 3 14  ? 139.236 135.863 191.056 1.00 98.39  ? 14  LYS G O   1 
ATOM   4709 C  CB  . LYS C 3 14  ? 141.883 134.085 190.277 1.00 97.12  ? 14  LYS G CB  1 
ATOM   4710 C  CG  . LYS C 3 14  ? 143.347 133.994 190.669 1.00 97.66  ? 14  LYS G CG  1 
ATOM   4711 C  CD  . LYS C 3 14  ? 144.255 134.353 189.506 1.00 97.68  ? 14  LYS G CD  1 
ATOM   4712 C  CE  . LYS C 3 14  ? 144.003 133.450 188.314 1.00 96.98  ? 14  LYS G CE  1 
ATOM   4713 N  NZ  . LYS C 3 14  ? 145.012 133.665 187.244 1.00 98.53  ? 14  LYS G NZ  1 
ATOM   4714 N  N   . LEU C 3 15  ? 138.722 133.732 190.550 1.00 96.98  ? 15  LEU G N   1 
ATOM   4715 C  CA  . LEU C 3 15  ? 137.366 134.084 190.143 1.00 96.44  ? 15  LEU G CA  1 
ATOM   4716 C  C   . LEU C 3 15  ? 136.556 134.609 191.318 1.00 95.23  ? 15  LEU G C   1 
ATOM   4717 O  O   . LEU C 3 15  ? 135.819 135.591 191.182 1.00 96.77  ? 15  LEU G O   1 
ATOM   4718 C  CB  . LEU C 3 15  ? 136.673 132.878 189.513 1.00 97.20  ? 15  LEU G CB  1 
ATOM   4719 C  CG  . LEU C 3 15  ? 135.352 133.172 188.802 1.00 96.58  ? 15  LEU G CG  1 
ATOM   4720 C  CD1 . LEU C 3 15  ? 135.507 134.343 187.847 1.00 95.21  ? 15  LEU G CD1 1 
ATOM   4721 C  CD2 . LEU C 3 15  ? 134.855 131.942 188.064 1.00 97.01  ? 15  LEU G CD2 1 
ATOM   4722 N  N   . VAL C 3 16  ? 136.680 133.969 192.482 1.00 95.26  ? 16  VAL G N   1 
ATOM   4723 C  CA  . VAL C 3 16  ? 135.949 134.429 193.659 1.00 96.96  ? 16  VAL G CA  1 
ATOM   4724 C  C   . VAL C 3 16  ? 136.411 135.824 194.062 1.00 94.71  ? 16  VAL G C   1 
ATOM   4725 O  O   . VAL C 3 16  ? 135.594 136.691 194.392 1.00 95.07  ? 16  VAL G O   1 
ATOM   4726 C  CB  . VAL C 3 16  ? 136.100 133.419 194.810 1.00 97.31  ? 16  VAL G CB  1 
ATOM   4727 C  CG1 . VAL C 3 16  ? 135.930 134.104 196.155 1.00 96.35  ? 16  VAL G CG1 1 
ATOM   4728 C  CG2 . VAL C 3 16  ? 135.089 132.300 194.655 1.00 96.55  ? 16  VAL G CG2 1 
ATOM   4729 N  N   . GLU C 3 17  ? 137.723 136.068 194.032 1.00 87.54  ? 17  GLU G N   1 
ATOM   4730 C  CA  . GLU C 3 17  ? 138.232 137.392 194.378 1.00 89.44  ? 17  GLU G CA  1 
ATOM   4731 C  C   . GLU C 3 17  ? 137.744 138.452 193.396 1.00 90.18  ? 17  GLU G C   1 
ATOM   4732 O  O   . GLU C 3 17  ? 137.347 139.554 193.802 1.00 89.72  ? 17  GLU G O   1 
ATOM   4733 C  CB  . GLU C 3 17  ? 139.759 137.367 194.422 1.00 90.03  ? 17  GLU G CB  1 
ATOM   4734 C  CG  . GLU C 3 17  ? 140.364 138.368 195.386 1.00 91.45  ? 17  GLU G CG  1 
ATOM   4735 C  CD  . GLU C 3 17  ? 140.050 138.041 196.831 1.00 92.59  ? 17  GLU G CD  1 
ATOM   4736 O  OE1 . GLU C 3 17  ? 140.120 136.850 197.200 1.00 91.40  ? 17  GLU G OE1 1 
ATOM   4737 O  OE2 . GLU C 3 17  ? 139.733 138.975 197.597 1.00 91.88  ? 17  GLU G OE2 1 
ATOM   4738 N  N   . GLN C 3 18  ? 137.773 138.139 192.098 1.00 82.99  ? 18  GLN G N   1 
ATOM   4739 C  CA  . GLN C 3 18  ? 137.321 139.094 191.093 1.00 80.08  ? 18  GLN G CA  1 
ATOM   4740 C  C   . GLN C 3 18  ? 135.838 139.400 191.249 1.00 80.90  ? 18  GLN G C   1 
ATOM   4741 O  O   . GLN C 3 18  ? 135.426 140.561 191.158 1.00 81.74  ? 18  GLN G O   1 
ATOM   4742 C  CB  . GLN C 3 18  ? 137.619 138.558 189.693 1.00 79.71  ? 18  GLN G CB  1 
ATOM   4743 C  CG  . GLN C 3 18  ? 137.130 139.446 188.562 1.00 79.72  ? 18  GLN G CG  1 
ATOM   4744 C  CD  . GLN C 3 18  ? 137.919 140.732 188.444 1.00 80.07  ? 18  GLN G CD  1 
ATOM   4745 O  OE1 . GLN C 3 18  ? 139.121 140.761 188.700 1.00 81.10  ? 18  GLN G OE1 1 
ATOM   4746 N  NE2 . GLN C 3 18  ? 137.246 141.804 188.050 1.00 79.60  ? 18  GLN G NE2 1 
ATOM   4747 N  N   . LEU C 3 19  ? 135.020 138.374 191.493 1.00 87.25  ? 19  LEU G N   1 
ATOM   4748 C  CA  . LEU C 3 19  ? 133.593 138.603 191.693 1.00 83.98  ? 19  LEU G CA  1 
ATOM   4749 C  C   . LEU C 3 19  ? 133.337 139.405 192.961 1.00 83.90  ? 19  LEU G C   1 
ATOM   4750 O  O   . LEU C 3 19  ? 132.430 140.244 192.998 1.00 87.82  ? 19  LEU G O   1 
ATOM   4751 C  CB  . LEU C 3 19  ? 132.848 137.272 191.732 1.00 84.86  ? 19  LEU G CB  1 
ATOM   4752 C  CG  . LEU C 3 19  ? 132.828 136.477 190.426 1.00 87.58  ? 19  LEU G CG  1 
ATOM   4753 C  CD1 . LEU C 3 19  ? 131.668 135.513 190.408 1.00 86.50  ? 19  LEU G CD1 1 
ATOM   4754 C  CD2 . LEU C 3 19  ? 132.759 137.402 189.230 1.00 87.11  ? 19  LEU G CD2 1 
ATOM   4755 N  N   . LYS C 3 20  ? 134.126 139.165 194.010 1.00 83.96  ? 20  LYS G N   1 
ATOM   4756 C  CA  . LYS C 3 20  ? 134.000 139.952 195.231 1.00 86.28  ? 20  LYS G CA  1 
ATOM   4757 C  C   . LYS C 3 20  ? 134.268 141.423 194.959 1.00 84.79  ? 20  LYS G C   1 
ATOM   4758 O  O   . LYS C 3 20  ? 133.474 142.293 195.334 1.00 84.84  ? 20  LYS G O   1 
ATOM   4759 C  CB  . LYS C 3 20  ? 134.968 139.431 196.293 1.00 86.54  ? 20  LYS G CB  1 
ATOM   4760 C  CG  . LYS C 3 20  ? 134.430 138.313 197.163 1.00 86.07  ? 20  LYS G CG  1 
ATOM   4761 C  CD  . LYS C 3 20  ? 135.542 137.745 198.029 1.00 84.93  ? 20  LYS G CD  1 
ATOM   4762 C  CE  . LYS C 3 20  ? 135.058 136.579 198.868 1.00 86.63  ? 20  LYS G CE  1 
ATOM   4763 N  NZ  . LYS C 3 20  ? 136.201 135.825 199.450 1.00 86.20  ? 20  LYS G NZ  1 
ATOM   4764 N  N   . MET C 3 21  ? 135.386 141.722 194.300 1.00 77.83  ? 21  MET G N   1 
ATOM   4765 C  CA  . MET C 3 21  ? 135.748 143.112 194.060 1.00 76.61  ? 21  MET G CA  1 
ATOM   4766 C  C   . MET C 3 21  ? 134.945 143.747 192.933 1.00 76.87  ? 21  MET G C   1 
ATOM   4767 O  O   . MET C 3 21  ? 135.026 144.964 192.749 1.00 76.97  ? 21  MET G O   1 
ATOM   4768 C  CB  . MET C 3 21  ? 137.249 143.219 193.778 1.00 77.26  ? 21  MET G CB  1 
ATOM   4769 C  CG  . MET C 3 21  ? 137.650 143.154 192.322 1.00 78.26  ? 21  MET G CG  1 
ATOM   4770 S  SD  . MET C 3 21  ? 139.382 143.623 192.135 1.00 87.92  ? 21  MET G SD  1 
ATOM   4771 C  CE  . MET C 3 21  ? 139.382 144.334 190.495 1.00 76.24  ? 21  MET G CE  1 
ATOM   4772 N  N   . GLU C 3 22  ? 134.176 142.960 192.182 1.00 71.72  ? 22  GLU G N   1 
ATOM   4773 C  CA  . GLU C 3 22  ? 133.234 143.505 191.215 1.00 69.17  ? 22  GLU G CA  1 
ATOM   4774 C  C   . GLU C 3 22  ? 131.838 143.702 191.786 1.00 69.14  ? 22  GLU G C   1 
ATOM   4775 O  O   . GLU C 3 22  ? 131.060 144.480 191.225 1.00 69.97  ? 22  GLU G O   1 
ATOM   4776 C  CB  . GLU C 3 22  ? 133.136 142.587 189.994 1.00 68.30  ? 22  GLU G CB  1 
ATOM   4777 C  CG  . GLU C 3 22  ? 134.212 142.803 188.956 1.00 69.26  ? 22  GLU G CG  1 
ATOM   4778 C  CD  . GLU C 3 22  ? 133.990 141.963 187.719 1.00 71.35  ? 22  GLU G CD  1 
ATOM   4779 O  OE1 . GLU C 3 22  ? 132.826 141.593 187.461 1.00 69.74  ? 22  GLU G OE1 1 
ATOM   4780 O  OE2 . GLU C 3 22  ? 134.975 141.672 187.008 1.00 69.84  ? 22  GLU G OE2 1 
ATOM   4781 N  N   . ALA C 3 23  ? 131.494 143.010 192.872 1.00 79.80  ? 23  ALA G N   1 
ATOM   4782 C  CA  . ALA C 3 23  ? 130.167 143.158 193.454 1.00 79.85  ? 23  ALA G CA  1 
ATOM   4783 C  C   . ALA C 3 23  ? 130.046 144.375 194.359 1.00 82.27  ? 23  ALA G C   1 
ATOM   4784 O  O   . ALA C 3 23  ? 128.924 144.778 194.677 1.00 84.12  ? 23  ALA G O   1 
ATOM   4785 C  CB  . ALA C 3 23  ? 129.789 141.903 194.242 1.00 79.54  ? 23  ALA G CB  1 
ATOM   4786 N  N   . ASN C 3 24  ? 131.159 144.972 194.777 1.00 85.33  ? 24  ASN G N   1 
ATOM   4787 C  CA  . ASN C 3 24  ? 131.128 146.150 195.637 1.00 84.50  ? 24  ASN G CA  1 
ATOM   4788 C  C   . ASN C 3 24  ? 131.560 147.352 194.805 1.00 84.84  ? 24  ASN G C   1 
ATOM   4789 O  O   . ASN C 3 24  ? 132.706 147.798 194.861 1.00 86.66  ? 24  ASN G O   1 
ATOM   4790 C  CB  . ASN C 3 24  ? 132.032 145.963 196.862 1.00 85.72  ? 24  ASN G CB  1 
ATOM   4791 C  CG  . ASN C 3 24  ? 131.539 144.876 197.795 1.00 87.28  ? 24  ASN G CG  1 
ATOM   4792 O  OD1 . ASN C 3 24  ? 132.197 143.852 197.976 1.00 88.31  ? 24  ASN G OD1 1 
ATOM   4793 N  ND2 . ASN C 3 24  ? 130.378 145.097 198.400 1.00 85.70  ? 24  ASN G ND2 1 
ATOM   4794 N  N   . ILE C 3 25  ? 130.613 147.891 194.038 1.00 79.48  ? 25  ILE G N   1 
ATOM   4795 C  CA  . ILE C 3 25  ? 130.771 149.143 193.309 1.00 79.34  ? 25  ILE G CA  1 
ATOM   4796 C  C   . ILE C 3 25  ? 129.430 149.863 193.358 1.00 80.91  ? 25  ILE G C   1 
ATOM   4797 O  O   . ILE C 3 25  ? 128.404 149.285 193.721 1.00 81.40  ? 25  ILE G O   1 
ATOM   4798 C  CB  . ILE C 3 25  ? 131.227 148.952 191.843 1.00 78.41  ? 25  ILE G CB  1 
ATOM   4799 C  CG1 . ILE C 3 25  ? 130.057 148.542 190.953 1.00 79.44  ? 25  ILE G CG1 1 
ATOM   4800 C  CG2 . ILE C 3 25  ? 132.350 147.934 191.724 1.00 79.56  ? 25  ILE G CG2 1 
ATOM   4801 C  CD1 . ILE C 3 25  ? 130.439 148.405 189.502 1.00 77.82  ? 25  ILE G CD1 1 
ATOM   4802 N  N   . ASP C 3 26  ? 129.443 151.137 192.988 1.00 80.78  ? 26  ASP G N   1 
ATOM   4803 C  CA  . ASP C 3 26  ? 128.245 151.960 193.029 1.00 79.62  ? 26  ASP G CA  1 
ATOM   4804 C  C   . ASP C 3 26  ? 127.601 152.019 191.651 1.00 78.51  ? 26  ASP G C   1 
ATOM   4805 O  O   . ASP C 3 26  ? 128.284 152.204 190.641 1.00 79.13  ? 26  ASP G O   1 
ATOM   4806 C  CB  . ASP C 3 26  ? 128.569 153.370 193.524 1.00 79.07  ? 26  ASP G CB  1 
ATOM   4807 C  CG  . ASP C 3 26  ? 128.598 153.461 195.038 1.00 81.64  ? 26  ASP G CG  1 
ATOM   4808 O  OD1 . ASP C 3 26  ? 129.200 152.573 195.678 1.00 81.89  ? 26  ASP G OD1 1 
ATOM   4809 O  OD2 . ASP C 3 26  ? 128.017 154.419 195.589 1.00 82.05  ? 26  ASP G OD2 1 
ATOM   4810 N  N   . ARG C 3 27  ? 126.284 151.856 191.619 1.00 65.95  ? 27  ARG G N   1 
ATOM   4811 C  CA  . ARG C 3 27  ? 125.517 151.866 190.386 1.00 63.85  ? 27  ARG G CA  1 
ATOM   4812 C  C   . ARG C 3 27  ? 124.420 152.916 190.474 1.00 65.64  ? 27  ARG G C   1 
ATOM   4813 O  O   . ARG C 3 27  ? 123.902 153.206 191.556 1.00 66.34  ? 27  ARG G O   1 
ATOM   4814 C  CB  . ARG C 3 27  ? 124.889 150.498 190.110 1.00 64.83  ? 27  ARG G CB  1 
ATOM   4815 C  CG  . ARG C 3 27  ? 125.874 149.400 189.757 1.00 66.98  ? 27  ARG G CG  1 
ATOM   4816 C  CD  . ARG C 3 27  ? 125.190 148.042 189.768 1.00 66.23  ? 27  ARG G CD  1 
ATOM   4817 N  NE  . ARG C 3 27  ? 126.141 146.940 189.688 1.00 68.74  ? 27  ARG G NE  1 
ATOM   4818 C  CZ  . ARG C 3 27  ? 126.845 146.478 190.711 1.00 66.20  ? 27  ARG G CZ  1 
ATOM   4819 N  NH1 . ARG C 3 27  ? 126.739 147.005 191.918 1.00 63.89  ? 27  ARG G NH1 1 
ATOM   4820 N  NH2 . ARG C 3 27  ? 127.679 145.461 190.518 1.00 63.06  ? 27  ARG G NH2 1 
ATOM   4821 N  N   . ILE C 3 28  ? 124.070 153.484 189.326 1.00 62.74  ? 28  ILE G N   1 
ATOM   4822 C  CA  . ILE C 3 28  ? 122.983 154.447 189.232 1.00 61.86  ? 28  ILE G CA  1 
ATOM   4823 C  C   . ILE C 3 28  ? 121.853 153.821 188.428 1.00 61.90  ? 28  ILE G C   1 
ATOM   4824 O  O   . ILE C 3 28  ? 122.038 152.841 187.702 1.00 63.90  ? 28  ILE G O   1 
ATOM   4825 C  CB  . ILE C 3 28  ? 123.434 155.783 188.605 1.00 61.31  ? 28  ILE G CB  1 
ATOM   4826 C  CG1 . ILE C 3 28  ? 123.883 155.577 187.158 1.00 60.82  ? 28  ILE G CG1 1 
ATOM   4827 C  CG2 . ILE C 3 28  ? 124.551 156.400 189.421 1.00 58.93  ? 28  ILE G CG2 1 
ATOM   4828 C  CD1 . ILE C 3 28  ? 124.061 156.855 186.385 1.00 57.92  ? 28  ILE G CD1 1 
ATOM   4829 N  N   . LYS C 3 29  ? 120.665 154.397 188.568 1.00 60.10  ? 29  LYS G N   1 
ATOM   4830 C  CA  . LYS C 3 29  ? 119.489 153.850 187.910 1.00 61.04  ? 29  LYS G CA  1 
ATOM   4831 C  C   . LYS C 3 29  ? 119.608 153.972 186.396 1.00 59.94  ? 29  LYS G C   1 
ATOM   4832 O  O   . LYS C 3 29  ? 120.308 154.840 185.874 1.00 63.17  ? 29  LYS G O   1 
ATOM   4833 C  CB  . LYS C 3 29  ? 118.230 154.565 188.394 1.00 62.41  ? 29  LYS G CB  1 
ATOM   4834 C  CG  . LYS C 3 29  ? 117.975 154.424 189.879 1.00 61.97  ? 29  LYS G CG  1 
ATOM   4835 C  CD  . LYS C 3 29  ? 116.915 153.374 190.152 1.00 64.64  ? 29  LYS G CD  1 
ATOM   4836 C  CE  . LYS C 3 29  ? 116.766 153.112 191.638 1.00 64.97  ? 29  LYS G CE  1 
ATOM   4837 N  NZ  . LYS C 3 29  ? 118.013 152.545 192.220 1.00 66.56  ? 29  LYS G NZ  1 
ATOM   4838 N  N   . VAL C 3 30  ? 118.913 153.079 185.689 1.00 59.37  ? 30  VAL G N   1 
ATOM   4839 C  CA  . VAL C 3 30  ? 118.931 153.092 184.229 1.00 58.81  ? 30  VAL G CA  1 
ATOM   4840 C  C   . VAL C 3 30  ? 118.334 154.382 183.690 1.00 58.63  ? 30  VAL G C   1 
ATOM   4841 O  O   . VAL C 3 30  ? 118.734 154.864 182.623 1.00 59.79  ? 30  VAL G O   1 
ATOM   4842 C  CB  . VAL C 3 30  ? 118.190 151.856 183.682 1.00 59.60  ? 30  VAL G CB  1 
ATOM   4843 C  CG1 . VAL C 3 30  ? 118.149 151.880 182.170 1.00 56.73  ? 30  VAL G CG1 1 
ATOM   4844 C  CG2 . VAL C 3 30  ? 118.853 150.588 184.169 1.00 59.85  ? 30  VAL G CG2 1 
ATOM   4845 N  N   . SER C 3 31  ? 117.370 154.960 184.408 1.00 62.71  ? 31  SER G N   1 
ATOM   4846 C  CA  . SER C 3 31  ? 116.748 156.195 183.947 1.00 60.88  ? 31  SER G CA  1 
ATOM   4847 C  C   . SER C 3 31  ? 117.768 157.317 183.833 1.00 59.03  ? 31  SER G C   1 
ATOM   4848 O  O   . SER C 3 31  ? 117.769 158.065 182.850 1.00 62.20  ? 31  SER G O   1 
ATOM   4849 C  CB  . SER C 3 31  ? 115.617 156.597 184.892 1.00 61.92  ? 31  SER G CB  1 
ATOM   4850 O  OG  . SER C 3 31  ? 114.469 155.800 184.676 1.00 64.12  ? 31  SER G OG  1 
ATOM   4851 N  N   . LYS C 3 32  ? 118.650 157.443 184.825 1.00 55.28  ? 32  LYS G N   1 
ATOM   4852 C  CA  . LYS C 3 32  ? 119.653 158.501 184.791 1.00 56.06  ? 32  LYS G CA  1 
ATOM   4853 C  C   . LYS C 3 32  ? 120.606 158.327 183.613 1.00 56.11  ? 32  LYS G C   1 
ATOM   4854 O  O   . LYS C 3 32  ? 120.926 159.296 182.915 1.00 61.22  ? 32  LYS G O   1 
ATOM   4855 C  CB  . LYS C 3 32  ? 120.419 158.525 186.111 1.00 54.02  ? 32  LYS G CB  1 
ATOM   4856 C  CG  . LYS C 3 32  ? 120.970 159.882 186.486 1.00 59.25  ? 32  LYS G CG  1 
ATOM   4857 C  CD  . LYS C 3 32  ? 121.378 159.917 187.946 1.00 61.74  ? 32  LYS G CD  1 
ATOM   4858 C  CE  . LYS C 3 32  ? 122.714 160.618 188.131 1.00 62.19  ? 32  LYS G CE  1 
ATOM   4859 N  NZ  . LYS C 3 32  ? 122.679 162.026 187.654 1.00 61.29  ? 32  LYS G NZ  1 
ATOM   4860 N  N   . ALA C 3 33  ? 121.058 157.097 183.368 1.00 51.15  ? 33  ALA G N   1 
ATOM   4861 C  CA  . ALA C 3 33  ? 121.974 156.845 182.261 1.00 48.80  ? 33  ALA G CA  1 
ATOM   4862 C  C   . ALA C 3 33  ? 121.313 157.103 180.914 1.00 52.32  ? 33  ALA G C   1 
ATOM   4863 O  O   . ALA C 3 33  ? 121.931 157.683 180.012 1.00 55.69  ? 33  ALA G O   1 
ATOM   4864 C  CB  . ALA C 3 33  ? 122.495 155.414 182.335 1.00 47.68  ? 33  ALA G CB  1 
ATOM   4865 N  N   . ALA C 3 34  ? 120.062 156.668 180.752 1.00 52.22  ? 34  ALA G N   1 
ATOM   4866 C  CA  . ALA C 3 34  ? 119.355 156.905 179.496 1.00 52.08  ? 34  ALA G CA  1 
ATOM   4867 C  C   . ALA C 3 34  ? 119.119 158.391 179.268 1.00 49.97  ? 34  ALA G C   1 
ATOM   4868 O  O   . ALA C 3 34  ? 119.269 158.887 178.144 1.00 50.29  ? 34  ALA G O   1 
ATOM   4869 C  CB  . ALA C 3 34  ? 118.035 156.140 179.486 1.00 51.58  ? 34  ALA G CB  1 
ATOM   4870 N  N   . ALA C 3 35  ? 118.759 159.123 180.324 1.00 45.31  ? 35  ALA G N   1 
ATOM   4871 C  CA  . ALA C 3 35  ? 118.588 160.564 180.200 1.00 44.97  ? 35  ALA G CA  1 
ATOM   4872 C  C   . ALA C 3 35  ? 119.894 161.242 179.815 1.00 49.15  ? 35  ALA G C   1 
ATOM   4873 O  O   . ALA C 3 35  ? 119.903 162.152 178.982 1.00 57.19  ? 35  ALA G O   1 
ATOM   4874 C  CB  . ALA C 3 35  ? 118.050 161.141 181.506 1.00 43.97  ? 35  ALA G CB  1 
ATOM   4875 N  N   . ASP C 3 36  ? 121.010 160.814 180.410 1.00 45.68  ? 36  ASP G N   1 
ATOM   4876 C  CA  . ASP C 3 36  ? 122.295 161.423 180.082 1.00 40.85  ? 36  ASP G CA  1 
ATOM   4877 C  C   . ASP C 3 36  ? 122.694 161.153 178.635 1.00 40.10  ? 36  ASP G C   1 
ATOM   4878 O  O   . ASP C 3 36  ? 123.182 162.055 177.944 1.00 46.67  ? 36  ASP G O   1 
ATOM   4879 C  CB  . ASP C 3 36  ? 123.371 160.922 181.040 1.00 44.95  ? 36  ASP G CB  1 
ATOM   4880 C  CG  . ASP C 3 36  ? 123.205 161.477 182.438 1.00 46.98  ? 36  ASP G CG  1 
ATOM   4881 O  OD1 . ASP C 3 36  ? 122.148 162.078 182.713 1.00 49.38  ? 36  ASP G OD1 1 
ATOM   4882 O  OD2 . ASP C 3 36  ? 124.128 161.314 183.262 1.00 45.75  ? 36  ASP G OD2 1 
ATOM   4883 N  N   . LEU C 3 37  ? 122.505 159.921 178.158 1.00 35.52  ? 37  LEU G N   1 
ATOM   4884 C  CA  . LEU C 3 37  ? 122.832 159.624 176.765 1.00 37.23  ? 37  LEU G CA  1 
ATOM   4885 C  C   . LEU C 3 37  ? 121.955 160.419 175.808 1.00 41.62  ? 37  LEU G C   1 
ATOM   4886 O  O   . LEU C 3 37  ? 122.442 160.953 174.802 1.00 43.61  ? 37  LEU G O   1 
ATOM   4887 C  CB  . LEU C 3 37  ? 122.696 158.129 176.494 1.00 37.42  ? 37  LEU G CB  1 
ATOM   4888 C  CG  . LEU C 3 37  ? 123.993 157.333 176.389 1.00 41.75  ? 37  LEU G CG  1 
ATOM   4889 C  CD1 . LEU C 3 37  ? 124.690 157.242 177.731 1.00 46.29  ? 37  LEU G CD1 1 
ATOM   4890 C  CD2 . LEU C 3 37  ? 123.702 155.959 175.851 1.00 40.76  ? 37  LEU G CD2 1 
ATOM   4891 N  N   . MET C 3 38  ? 120.656 160.513 176.107 1.00 42.41  ? 38  MET G N   1 
ATOM   4892 C  CA  . MET C 3 38  ? 119.753 161.292 175.267 1.00 40.14  ? 38  MET G CA  1 
ATOM   4893 C  C   . MET C 3 38  ? 120.151 162.764 175.247 1.00 41.82  ? 38  MET G C   1 
ATOM   4894 O  O   . MET C 3 38  ? 120.125 163.408 174.192 1.00 46.07  ? 38  MET G O   1 
ATOM   4895 C  CB  . MET C 3 38  ? 118.321 161.128 175.770 1.00 41.34  ? 38  MET G CB  1 
ATOM   4896 C  CG  . MET C 3 38  ? 117.296 161.963 175.040 1.00 48.26  ? 38  MET G CG  1 
ATOM   4897 S  SD  . MET C 3 38  ? 115.620 161.691 175.632 1.00 54.68  ? 38  MET G SD  1 
ATOM   4898 C  CE  . MET C 3 38  ? 115.684 162.527 177.208 1.00 41.48  ? 38  MET G CE  1 
ATOM   4899 N  N   . ALA C 3 39  ? 120.526 163.311 176.405 1.00 33.98  ? 39  ALA G N   1 
ATOM   4900 C  CA  . ALA C 3 39  ? 120.932 164.709 176.473 1.00 35.10  ? 39  ALA G CA  1 
ATOM   4901 C  C   . ALA C 3 39  ? 122.210 164.961 175.684 1.00 37.72  ? 39  ALA G C   1 
ATOM   4902 O  O   . ALA C 3 39  ? 122.329 165.985 175.001 1.00 40.97  ? 39  ALA G O   1 
ATOM   4903 C  CB  . ALA C 3 39  ? 121.109 165.132 177.928 1.00 39.27  ? 39  ALA G CB  1 
ATOM   4904 N  N   . TYR C 3 40  ? 123.183 164.050 175.771 1.00 32.73  ? 40  TYR G N   1 
ATOM   4905 C  CA  . TYR C 3 40  ? 124.391 164.209 174.967 1.00 24.72  ? 40  TYR G CA  1 
ATOM   4906 C  C   . TYR C 3 40  ? 124.063 164.183 173.484 1.00 29.86  ? 40  TYR G C   1 
ATOM   4907 O  O   . TYR C 3 40  ? 124.583 164.989 172.708 1.00 37.46  ? 40  TYR G O   1 
ATOM   4908 C  CB  . TYR C 3 40  ? 125.416 163.127 175.295 1.00 28.86  ? 40  TYR G CB  1 
ATOM   4909 C  CG  . TYR C 3 40  ? 126.710 163.297 174.532 1.00 28.54  ? 40  TYR G CG  1 
ATOM   4910 C  CD1 . TYR C 3 40  ? 126.862 162.788 173.252 1.00 31.18  ? 40  TYR G CD1 1 
ATOM   4911 C  CD2 . TYR C 3 40  ? 127.773 163.982 175.088 1.00 31.16  ? 40  TYR G CD2 1 
ATOM   4912 C  CE1 . TYR C 3 40  ? 128.031 162.956 172.555 1.00 30.92  ? 40  TYR G CE1 1 
ATOM   4913 C  CE2 . TYR C 3 40  ? 128.950 164.147 174.399 1.00 31.88  ? 40  TYR G CE2 1 
ATOM   4914 C  CZ  . TYR C 3 40  ? 129.074 163.635 173.135 1.00 31.16  ? 40  TYR G CZ  1 
ATOM   4915 O  OH  . TYR C 3 40  ? 130.252 163.807 172.449 1.00 29.46  ? 40  TYR G OH  1 
ATOM   4916 N  N   . CYS C 3 41  ? 123.208 163.248 173.064 1.00 41.05  ? 41  CYS G N   1 
ATOM   4917 C  CA  . CYS C 3 41  ? 122.862 163.169 171.648 1.00 37.32  ? 41  CYS G CA  1 
ATOM   4918 C  C   . CYS C 3 41  ? 122.162 164.438 171.183 1.00 33.58  ? 41  CYS G C   1 
ATOM   4919 O  O   . CYS C 3 41  ? 122.386 164.904 170.062 1.00 34.14  ? 41  CYS G O   1 
ATOM   4920 C  CB  . CYS C 3 41  ? 121.987 161.946 171.386 1.00 33.68  ? 41  CYS G CB  1 
ATOM   4921 S  SG  . CYS C 3 41  ? 122.890 160.501 170.832 1.00 39.24  ? 41  CYS G SG  1 
ATOM   4922 N  N   . GLU C 3 42  ? 121.306 165.007 172.032 1.00 42.69  ? 42  GLU G N   1 
ATOM   4923 C  CA  . GLU C 3 42  ? 120.572 166.211 171.655 1.00 41.02  ? 42  GLU G CA  1 
ATOM   4924 C  C   . GLU C 3 42  ? 121.479 167.436 171.606 1.00 42.15  ? 42  GLU G C   1 
ATOM   4925 O  O   . GLU C 3 42  ? 121.289 168.319 170.764 1.00 45.72  ? 42  GLU G O   1 
ATOM   4926 C  CB  . GLU C 3 42  ? 119.412 166.431 172.624 1.00 42.47  ? 42  GLU G CB  1 
ATOM   4927 C  CG  . GLU C 3 42  ? 118.706 167.764 172.495 1.00 45.79  ? 42  GLU G CG  1 
ATOM   4928 C  CD  . GLU C 3 42  ? 119.124 168.747 173.569 1.00 49.14  ? 42  GLU G CD  1 
ATOM   4929 O  OE1 . GLU C 3 42  ? 119.538 168.300 174.658 1.00 44.92  ? 42  GLU G OE1 1 
ATOM   4930 O  OE2 . GLU C 3 42  ? 119.032 169.969 173.329 1.00 51.40  ? 42  GLU G OE2 1 
ATOM   4931 N  N   . ALA C 3 43  ? 122.474 167.510 172.493 1.00 39.33  ? 43  ALA G N   1 
ATOM   4932 C  CA  . ALA C 3 43  ? 123.308 168.706 172.550 1.00 36.71  ? 43  ALA G CA  1 
ATOM   4933 C  C   . ALA C 3 43  ? 124.275 168.802 171.375 1.00 41.43  ? 43  ALA G C   1 
ATOM   4934 O  O   . ALA C 3 43  ? 124.848 169.869 171.140 1.00 45.78  ? 43  ALA G O   1 
ATOM   4935 C  CB  . ALA C 3 43  ? 124.083 168.746 173.864 1.00 36.85  ? 43  ALA G CB  1 
ATOM   4936 N  N   . HIS C 3 44  ? 124.481 167.712 170.636 1.00 42.79  ? 44  HIS G N   1 
ATOM   4937 C  CA  . HIS C 3 44  ? 125.430 167.676 169.529 1.00 40.05  ? 44  HIS G CA  1 
ATOM   4938 C  C   . HIS C 3 44  ? 124.761 167.292 168.215 1.00 42.50  ? 44  HIS G C   1 
ATOM   4939 O  O   . HIS C 3 44  ? 125.406 166.740 167.323 1.00 40.86  ? 44  HIS G O   1 
ATOM   4940 C  CB  . HIS C 3 44  ? 126.574 166.711 169.830 1.00 35.67  ? 44  HIS G CB  1 
ATOM   4941 C  CG  . HIS C 3 44  ? 127.359 167.063 171.053 1.00 37.11  ? 44  HIS G CG  1 
ATOM   4942 N  ND1 . HIS C 3 44  ? 128.698 167.377 171.011 1.00 40.61  ? 44  HIS G ND1 1 
ATOM   4943 C  CD2 . HIS C 3 44  ? 126.994 167.148 172.352 1.00 40.34  ? 44  HIS G CD2 1 
ATOM   4944 C  CE1 . HIS C 3 44  ? 129.125 167.640 172.232 1.00 43.49  ? 44  HIS G CE1 1 
ATOM   4945 N  NE2 . HIS C 3 44  ? 128.110 167.508 173.065 1.00 42.33  ? 44  HIS G NE2 1 
ATOM   4946 N  N   . ALA C 3 45  ? 123.464 167.571 168.087 1.00 43.99  ? 45  ALA G N   1 
ATOM   4947 C  CA  . ALA C 3 45  ? 122.723 167.186 166.894 1.00 41.50  ? 45  ALA G CA  1 
ATOM   4948 C  C   . ALA C 3 45  ? 123.110 168.010 165.675 1.00 46.05  ? 45  ALA G C   1 
ATOM   4949 O  O   . ALA C 3 45  ? 123.077 167.496 164.552 1.00 45.70  ? 45  ALA G O   1 
ATOM   4950 C  CB  . ALA C 3 45  ? 121.223 167.314 167.147 1.00 45.72  ? 45  ALA G CB  1 
ATOM   4951 N  N   . LYS C 3 46  ? 123.467 169.276 165.869 1.00 52.19  ? 46  LYS G N   1 
ATOM   4952 C  CA  . LYS C 3 46  ? 123.759 170.186 164.771 1.00 49.25  ? 46  LYS G CA  1 
ATOM   4953 C  C   . LYS C 3 46  ? 125.209 170.130 164.310 1.00 49.20  ? 46  LYS G C   1 
ATOM   4954 O  O   . LYS C 3 46  ? 125.586 170.889 163.414 1.00 50.96  ? 46  LYS G O   1 
ATOM   4955 C  CB  . LYS C 3 46  ? 123.403 171.617 165.174 1.00 46.39  ? 46  LYS G CB  1 
ATOM   4956 C  CG  . LYS C 3 46  ? 121.953 171.793 165.582 1.00 51.58  ? 46  LYS G CG  1 
ATOM   4957 C  CD  . LYS C 3 46  ? 121.015 171.482 164.425 1.00 53.23  ? 46  LYS G CD  1 
ATOM   4958 C  CE  . LYS C 3 46  ? 119.555 171.576 164.841 1.00 52.22  ? 46  LYS G CE  1 
ATOM   4959 N  NZ  . LYS C 3 46  ? 119.009 170.266 165.287 1.00 50.11  ? 46  LYS G NZ  1 
ATOM   4960 N  N   . GLU C 3 47  ? 126.032 169.266 164.900 1.00 46.46  ? 47  GLU G N   1 
ATOM   4961 C  CA  . GLU C 3 47  ? 127.414 169.092 164.478 1.00 41.44  ? 47  GLU G CA  1 
ATOM   4962 C  C   . GLU C 3 47  ? 127.677 167.699 163.922 1.00 44.74  ? 47  GLU G C   1 
ATOM   4963 O  O   . GLU C 3 47  ? 128.829 167.262 163.886 1.00 48.68  ? 47  GLU G O   1 
ATOM   4964 C  CB  . GLU C 3 47  ? 128.367 169.378 165.636 1.00 41.18  ? 47  GLU G CB  1 
ATOM   4965 C  CG  . GLU C 3 47  ? 127.930 170.502 166.543 1.00 41.48  ? 47  GLU G CG  1 
ATOM   4966 C  CD  . GLU C 3 47  ? 128.703 170.518 167.841 1.00 48.90  ? 47  GLU G CD  1 
ATOM   4967 O  OE1 . GLU C 3 47  ? 129.839 170.000 167.862 1.00 49.90  ? 47  GLU G OE1 1 
ATOM   4968 O  OE2 . GLU C 3 47  ? 128.178 171.046 168.842 1.00 50.53  ? 47  GLU G OE2 1 
ATOM   4969 N  N   . ASP C 3 48  ? 126.638 166.992 163.489 1.00 34.13  ? 48  ASP G N   1 
ATOM   4970 C  CA  . ASP C 3 48  ? 126.801 165.659 162.919 1.00 32.69  ? 48  ASP G CA  1 
ATOM   4971 C  C   . ASP C 3 48  ? 126.545 165.720 161.421 1.00 37.03  ? 48  ASP G C   1 
ATOM   4972 O  O   . ASP C 3 48  ? 125.382 165.750 160.991 1.00 36.43  ? 48  ASP G O   1 
ATOM   4973 C  CB  . ASP C 3 48  ? 125.848 164.668 163.590 1.00 32.77  ? 48  ASP G CB  1 
ATOM   4974 C  CG  . ASP C 3 48  ? 126.273 163.225 163.400 1.00 34.18  ? 48  ASP G CG  1 
ATOM   4975 O  OD1 . ASP C 3 48  ? 127.253 162.979 162.667 1.00 35.44  ? 48  ASP G OD1 1 
ATOM   4976 O  OD2 . ASP C 3 48  ? 125.623 162.333 163.984 1.00 22.54  ? 48  ASP G OD2 1 
ATOM   4977 N  N   . PRO C 3 49  ? 127.588 165.750 160.588 1.00 36.96  ? 49  PRO G N   1 
ATOM   4978 C  CA  . PRO C 3 49  ? 127.372 165.813 159.136 1.00 30.72  ? 49  PRO G CA  1 
ATOM   4979 C  C   . PRO C 3 49  ? 126.624 164.629 158.557 1.00 35.01  ? 49  PRO G C   1 
ATOM   4980 O  O   . PRO C 3 49  ? 125.966 164.784 157.524 1.00 40.51  ? 49  PRO G O   1 
ATOM   4981 C  CB  . PRO C 3 49  ? 128.798 165.896 158.589 1.00 30.45  ? 49  PRO G CB  1 
ATOM   4982 C  CG  . PRO C 3 49  ? 129.560 166.536 159.676 1.00 34.19  ? 49  PRO G CG  1 
ATOM   4983 C  CD  . PRO C 3 49  ? 128.996 165.982 160.938 1.00 32.10  ? 49  PRO G CD  1 
ATOM   4984 N  N   . LEU C 3 50  ? 126.723 163.443 159.158 1.00 36.48  ? 50  LEU G N   1 
ATOM   4985 C  CA  . LEU C 3 50  ? 125.980 162.299 158.643 1.00 29.83  ? 50  LEU G CA  1 
ATOM   4986 C  C   . LEU C 3 50  ? 124.510 162.350 159.034 1.00 30.50  ? 50  LEU G C   1 
ATOM   4987 O  O   . LEU C 3 50  ? 123.654 161.896 158.270 1.00 41.89  ? 50  LEU G O   1 
ATOM   4988 C  CB  . LEU C 3 50  ? 126.611 160.995 159.128 1.00 27.88  ? 50  LEU G CB  1 
ATOM   4989 C  CG  . LEU C 3 50  ? 128.081 160.757 158.777 1.00 30.95  ? 50  LEU G CG  1 
ATOM   4990 C  CD1 . LEU C 3 50  ? 128.586 159.513 159.468 1.00 33.19  ? 50  LEU G CD1 1 
ATOM   4991 C  CD2 . LEU C 3 50  ? 128.292 160.650 157.283 1.00 24.31  ? 50  LEU G CD2 1 
ATOM   4992 N  N   . LEU C 3 51  ? 124.200 162.883 160.212 1.00 32.35  ? 51  LEU G N   1 
ATOM   4993 C  CA  . LEU C 3 51  ? 122.813 163.039 160.632 1.00 36.89  ? 51  LEU G CA  1 
ATOM   4994 C  C   . LEU C 3 51  ? 122.134 164.198 159.914 1.00 38.93  ? 51  LEU G C   1 
ATOM   4995 O  O   . LEU C 3 51  ? 120.982 164.077 159.487 1.00 47.88  ? 51  LEU G O   1 
ATOM   4996 C  CB  . LEU C 3 51  ? 122.754 163.249 162.143 1.00 41.13  ? 51  LEU G CB  1 
ATOM   4997 C  CG  . LEU C 3 51  ? 121.441 163.040 162.880 1.00 34.20  ? 51  LEU G CG  1 
ATOM   4998 C  CD1 . LEU C 3 51  ? 121.124 161.575 162.911 1.00 39.24  ? 51  LEU G CD1 1 
ATOM   4999 C  CD2 . LEU C 3 51  ? 121.550 163.588 164.281 1.00 32.06  ? 51  LEU G CD2 1 
ATOM   5000 N  N   . THR C 3 52  ? 122.827 165.326 159.782 1.00 45.89  ? 52  THR G N   1 
ATOM   5001 C  CA  . THR C 3 52  ? 122.288 166.538 159.167 1.00 51.69  ? 52  THR G CA  1 
ATOM   5002 C  C   . THR C 3 52  ? 123.260 166.982 158.084 1.00 54.01  ? 52  THR G C   1 
ATOM   5003 O  O   . THR C 3 52  ? 124.178 167.771 158.347 1.00 51.18  ? 52  THR G O   1 
ATOM   5004 C  CB  . THR C 3 52  ? 122.077 167.635 160.208 1.00 53.61  ? 52  THR G CB  1 
ATOM   5005 O  OG1 . THR C 3 52  ? 121.216 167.148 161.243 1.00 51.31  ? 52  THR G OG1 1 
ATOM   5006 C  CG2 . THR C 3 52  ? 121.449 168.860 159.577 1.00 50.63  ? 52  THR G CG2 1 
ATOM   5007 N  N   . PRO C 3 53  ? 123.095 166.491 156.856 1.00 58.06  ? 53  PRO G N   1 
ATOM   5008 C  CA  . PRO C 3 53  ? 124.115 166.716 155.825 1.00 59.76  ? 53  PRO G CA  1 
ATOM   5009 C  C   . PRO C 3 53  ? 124.359 168.194 155.553 1.00 62.89  ? 53  PRO G C   1 
ATOM   5010 O  O   . PRO C 3 53  ? 123.446 169.019 155.608 1.00 61.20  ? 53  PRO G O   1 
ATOM   5011 C  CB  . PRO C 3 53  ? 123.539 166.001 154.599 1.00 58.15  ? 53  PRO G CB  1 
ATOM   5012 C  CG  . PRO C 3 53  ? 122.629 164.968 155.161 1.00 56.41  ? 53  PRO G CG  1 
ATOM   5013 C  CD  . PRO C 3 53  ? 122.043 165.567 156.401 1.00 55.21  ? 53  PRO G CD  1 
ATOM   5014 N  N   . VAL C 3 54  ? 125.618 168.513 155.268 1.00 73.87  ? 54  VAL G N   1 
ATOM   5015 C  CA  . VAL C 3 54  ? 126.092 169.878 155.058 1.00 72.96  ? 54  VAL G CA  1 
ATOM   5016 C  C   . VAL C 3 54  ? 125.846 170.293 153.611 1.00 74.89  ? 54  VAL G C   1 
ATOM   5017 O  O   . VAL C 3 54  ? 125.648 169.428 152.746 1.00 72.63  ? 54  VAL G O   1 
ATOM   5018 C  CB  . VAL C 3 54  ? 127.583 170.000 155.418 1.00 73.01  ? 54  VAL G CB  1 
ATOM   5019 C  CG1 . VAL C 3 54  ? 127.767 170.052 156.924 1.00 72.16  ? 54  VAL G CG1 1 
ATOM   5020 C  CG2 . VAL C 3 54  ? 128.363 168.845 154.822 1.00 70.14  ? 54  VAL G CG2 1 
ATOM   5021 N  N   . PRO C 3 55  ? 125.843 171.591 153.302 1.00 84.48  ? 55  PRO G N   1 
ATOM   5022 C  CA  . PRO C 3 55  ? 125.716 172.020 151.905 1.00 81.96  ? 55  PRO G CA  1 
ATOM   5023 C  C   . PRO C 3 55  ? 126.891 171.547 151.062 1.00 82.43  ? 55  PRO G C   1 
ATOM   5024 O  O   . PRO C 3 55  ? 127.983 171.275 151.562 1.00 84.17  ? 55  PRO G O   1 
ATOM   5025 C  CB  . PRO C 3 55  ? 125.687 173.548 152.003 1.00 81.83  ? 55  PRO G CB  1 
ATOM   5026 C  CG  . PRO C 3 55  ? 125.227 173.829 153.381 1.00 82.15  ? 55  PRO G CG  1 
ATOM   5027 C  CD  . PRO C 3 55  ? 125.768 172.728 154.234 1.00 83.06  ? 55  PRO G CD  1 
ATOM   5028 N  N   . ALA C 3 56  ? 126.650 171.462 149.751 1.00 84.33  ? 56  ALA G N   1 
ATOM   5029 C  CA  . ALA C 3 56  ? 127.640 170.904 148.837 1.00 85.26  ? 56  ALA G CA  1 
ATOM   5030 C  C   . ALA C 3 56  ? 128.922 171.722 148.785 1.00 86.41  ? 56  ALA G C   1 
ATOM   5031 O  O   . ALA C 3 56  ? 129.941 171.221 148.298 1.00 85.30  ? 56  ALA G O   1 
ATOM   5032 C  CB  . ALA C 3 56  ? 127.050 170.782 147.433 1.00 85.89  ? 56  ALA G CB  1 
ATOM   5033 N  N   . SER C 3 57  ? 128.900 172.968 149.262 1.00 84.71  ? 57  SER G N   1 
ATOM   5034 C  CA  . SER C 3 57  ? 130.123 173.764 149.284 1.00 83.75  ? 57  SER G CA  1 
ATOM   5035 C  C   . SER C 3 57  ? 131.061 173.308 150.394 1.00 84.07  ? 57  SER G C   1 
ATOM   5036 O  O   . SER C 3 57  ? 132.286 173.338 150.229 1.00 82.37  ? 57  SER G O   1 
ATOM   5037 C  CB  . SER C 3 57  ? 129.788 175.245 149.446 1.00 84.31  ? 57  SER G CB  1 
ATOM   5038 O  OG  . SER C 3 57  ? 130.967 176.027 149.515 1.00 83.70  ? 57  SER G OG  1 
ATOM   5039 N  N   . GLU C 3 58  ? 130.509 172.882 151.528 1.00 74.68  ? 58  GLU G N   1 
ATOM   5040 C  CA  . GLU C 3 58  ? 131.307 172.500 152.686 1.00 74.15  ? 58  GLU G CA  1 
ATOM   5041 C  C   . GLU C 3 58  ? 131.625 171.011 152.740 1.00 72.23  ? 58  GLU G C   1 
ATOM   5042 O  O   . GLU C 3 58  ? 132.254 170.566 153.703 1.00 73.11  ? 58  GLU G O   1 
ATOM   5043 C  CB  . GLU C 3 58  ? 130.598 172.920 153.975 1.00 73.80  ? 58  GLU G CB  1 
ATOM   5044 C  CG  . GLU C 3 58  ? 130.451 174.421 154.131 1.00 75.69  ? 58  GLU G CG  1 
ATOM   5045 C  CD  . GLU C 3 58  ? 129.259 174.805 154.979 1.00 77.20  ? 58  GLU G CD  1 
ATOM   5046 O  OE1 . GLU C 3 58  ? 128.127 174.792 154.455 1.00 74.89  ? 58  GLU G OE1 1 
ATOM   5047 O  OE2 . GLU C 3 58  ? 129.454 175.124 156.170 1.00 76.13  ? 58  GLU G OE2 1 
ATOM   5048 N  N   . ASN C 3 59  ? 131.210 170.237 151.748 1.00 52.81  ? 59  ASN G N   1 
ATOM   5049 C  CA  . ASN C 3 59  ? 131.589 168.834 151.677 1.00 50.69  ? 59  ASN G CA  1 
ATOM   5050 C  C   . ASN C 3 59  ? 132.961 168.716 151.026 1.00 52.43  ? 59  ASN G C   1 
ATOM   5051 O  O   . ASN C 3 59  ? 133.111 169.091 149.859 1.00 52.41  ? 59  ASN G O   1 
ATOM   5052 C  CB  . ASN C 3 59  ? 130.562 168.049 150.876 1.00 51.06  ? 59  ASN G CB  1 
ATOM   5053 C  CG  . ASN C 3 59  ? 130.736 166.554 151.005 1.00 54.55  ? 59  ASN G CG  1 
ATOM   5054 O  OD1 . ASN C 3 59  ? 131.182 166.056 152.036 1.00 48.94  ? 59  ASN G OD1 1 
ATOM   5055 N  ND2 . ASN C 3 59  ? 130.391 165.828 149.954 1.00 52.86  ? 59  ASN G ND2 1 
ATOM   5056 N  N   . PRO C 3 60  ? 133.982 168.220 151.731 1.00 48.44  ? 60  PRO G N   1 
ATOM   5057 C  CA  . PRO C 3 60  ? 135.306 168.078 151.115 1.00 40.54  ? 60  PRO G CA  1 
ATOM   5058 C  C   . PRO C 3 60  ? 135.419 166.925 150.135 1.00 40.17  ? 60  PRO G C   1 
ATOM   5059 O  O   . PRO C 3 60  ? 136.410 166.863 149.397 1.00 41.84  ? 60  PRO G O   1 
ATOM   5060 C  CB  . PRO C 3 60  ? 136.202 167.855 152.335 1.00 36.00  ? 60  PRO G CB  1 
ATOM   5061 C  CG  . PRO C 3 60  ? 135.301 167.090 153.228 1.00 37.47  ? 60  PRO G CG  1 
ATOM   5062 C  CD  . PRO C 3 60  ? 134.071 167.942 153.172 1.00 44.87  ? 60  PRO G CD  1 
ATOM   5063 N  N   . PHE C 3 61  ? 134.444 166.019 150.099 1.00 35.19  ? 61  PHE G N   1 
ATOM   5064 C  CA  . PHE C 3 61  ? 134.468 164.861 149.216 1.00 36.32  ? 61  PHE G CA  1 
ATOM   5065 C  C   . PHE C 3 61  ? 133.549 165.027 148.012 1.00 40.74  ? 61  PHE G C   1 
ATOM   5066 O  O   . PHE C 3 61  ? 133.143 164.029 147.411 1.00 39.56  ? 61  PHE G O   1 
ATOM   5067 C  CB  . PHE C 3 61  ? 134.088 163.600 149.993 1.00 35.64  ? 61  PHE G CB  1 
ATOM   5068 C  CG  . PHE C 3 61  ? 135.091 163.200 151.032 1.00 31.52  ? 61  PHE G CG  1 
ATOM   5069 C  CD1 . PHE C 3 61  ? 136.203 162.462 150.688 1.00 30.91  ? 61  PHE G CD1 1 
ATOM   5070 C  CD2 . PHE C 3 61  ? 134.918 163.562 152.355 1.00 29.70  ? 61  PHE G CD2 1 
ATOM   5071 C  CE1 . PHE C 3 61  ? 137.124 162.099 151.638 1.00 33.44  ? 61  PHE G CE1 1 
ATOM   5072 C  CE2 . PHE C 3 61  ? 135.837 163.200 153.309 1.00 33.08  ? 61  PHE G CE2 1 
ATOM   5073 C  CZ  . PHE C 3 61  ? 136.941 162.466 152.951 1.00 35.07  ? 61  PHE G CZ  1 
ATOM   5074 N  N   . ARG C 3 62  ? 133.208 166.262 147.659 1.00 48.67  ? 62  ARG G N   1 
ATOM   5075 C  CA  . ARG C 3 62  ? 132.308 166.547 146.544 1.00 46.32  ? 62  ARG G CA  1 
ATOM   5076 C  C   . ARG C 3 62  ? 132.796 165.938 145.235 1.00 44.49  ? 62  ARG G C   1 
ATOM   5077 O  O   . ARG C 3 62  ? 132.085 165.949 144.231 1.00 45.60  ? 62  ARG G O   1 
ATOM   5078 C  CB  . ARG C 3 62  ? 132.149 168.056 146.383 1.00 44.63  ? 62  ARG G CB  1 
ATOM   5079 C  CG  . ARG C 3 62  ? 133.420 168.814 146.708 1.00 43.14  ? 62  ARG G CG  1 
ATOM   5080 C  CD  . ARG C 3 62  ? 133.203 170.315 146.747 1.00 46.10  ? 62  ARG G CD  1 
ATOM   5081 N  NE  . ARG C 3 62  ? 134.097 170.982 147.689 1.00 51.62  ? 62  ARG G NE  1 
ATOM   5082 C  CZ  . ARG C 3 62  ? 135.419 171.028 147.584 1.00 50.90  ? 62  ARG G CZ  1 
ATOM   5083 N  NH1 . ARG C 3 62  ? 136.056 170.464 146.571 1.00 48.58  ? 62  ARG G NH1 1 
ATOM   5084 N  NH2 . ARG C 3 62  ? 136.121 171.665 148.517 1.00 48.36  ? 62  ARG G NH2 1 
ATOM   5085 N  N   . GLN D 4 23  ? 123.884 135.371 180.432 1.00 41.30  ? 1   GLN N N   1 
ATOM   5086 C  CA  . GLN D 4 23  ? 125.115 134.595 180.413 1.00 41.22  ? 1   GLN N CA  1 
ATOM   5087 C  C   . GLN D 4 23  ? 124.842 133.166 179.994 1.00 44.37  ? 1   GLN N C   1 
ATOM   5088 O  O   . GLN D 4 23  ? 123.878 132.561 180.449 1.00 45.08  ? 1   GLN N O   1 
ATOM   5089 C  CB  . GLN D 4 23  ? 125.788 134.610 181.780 1.00 39.74  ? 1   GLN N CB  1 
ATOM   5090 C  CG  . GLN D 4 23  ? 127.193 134.062 181.749 1.00 40.13  ? 1   GLN N CG  1 
ATOM   5091 C  CD  . GLN D 4 23  ? 127.841 134.046 183.108 1.00 47.70  ? 1   GLN N CD  1 
ATOM   5092 O  OE1 . GLN D 4 23  ? 127.219 134.400 184.108 1.00 47.37  ? 1   GLN N OE1 1 
ATOM   5093 N  NE2 . GLN D 4 23  ? 129.100 133.632 183.155 1.00 48.47  ? 1   GLN N NE2 1 
ATOM   5094 N  N   . VAL D 4 24  ? 125.694 132.626 179.126 1.00 39.79  ? 2   VAL N N   1 
ATOM   5095 C  CA  . VAL D 4 24  ? 125.503 131.268 178.632 1.00 37.21  ? 2   VAL N CA  1 
ATOM   5096 C  C   . VAL D 4 24  ? 125.800 130.292 179.761 1.00 38.16  ? 2   VAL N C   1 
ATOM   5097 O  O   . VAL D 4 24  ? 126.925 130.233 180.268 1.00 41.50  ? 2   VAL N O   1 
ATOM   5098 C  CB  . VAL D 4 24  ? 126.390 130.998 177.411 1.00 32.56  ? 2   VAL N CB  1 
ATOM   5099 C  CG1 . VAL D 4 24  ? 126.298 129.542 176.994 1.00 31.49  ? 2   VAL N CG1 1 
ATOM   5100 C  CG2 . VAL D 4 24  ? 125.994 131.901 176.265 1.00 34.06  ? 2   VAL N CG2 1 
ATOM   5101 N  N   . GLN D 4 25  ? 124.792 129.523 180.162 1.00 41.51  ? 3   GLN N N   1 
ATOM   5102 C  CA  . GLN D 4 25  ? 124.950 128.536 181.219 1.00 39.03  ? 3   GLN N CA  1 
ATOM   5103 C  C   . GLN D 4 25  ? 124.414 127.196 180.749 1.00 41.40  ? 3   GLN N C   1 
ATOM   5104 O  O   . GLN D 4 25  ? 123.315 127.126 180.193 1.00 46.74  ? 3   GLN N O   1 
ATOM   5105 C  CB  . GLN D 4 25  ? 124.224 128.963 182.493 1.00 41.69  ? 3   GLN N CB  1 
ATOM   5106 C  CG  . GLN D 4 25  ? 124.824 130.169 183.172 1.00 46.14  ? 3   GLN N CG  1 
ATOM   5107 C  CD  . GLN D 4 25  ? 124.135 130.495 184.473 1.00 51.02  ? 3   GLN N CD  1 
ATOM   5108 O  OE1 . GLN D 4 25  ? 123.630 129.607 185.159 1.00 51.58  ? 3   GLN N OE1 1 
ATOM   5109 N  NE2 . GLN D 4 25  ? 124.100 131.775 184.821 1.00 48.57  ? 3   GLN N NE2 1 
ATOM   5110 N  N   . LEU D 4 26  ? 125.195 126.140 180.964 1.00 38.48  ? 4   LEU N N   1 
ATOM   5111 C  CA  . LEU D 4 26  ? 124.749 124.767 180.772 1.00 36.74  ? 4   LEU N CA  1 
ATOM   5112 C  C   . LEU D 4 26  ? 125.041 124.003 182.052 1.00 35.72  ? 4   LEU N C   1 
ATOM   5113 O  O   . LEU D 4 26  ? 126.155 124.080 182.576 1.00 36.22  ? 4   LEU N O   1 
ATOM   5114 C  CB  . LEU D 4 26  ? 125.450 124.108 179.581 1.00 33.57  ? 4   LEU N CB  1 
ATOM   5115 C  CG  . LEU D 4 26  ? 125.345 124.804 178.223 1.00 35.53  ? 4   LEU N CG  1 
ATOM   5116 C  CD1 . LEU D 4 26  ? 126.693 124.900 177.584 1.00 30.90  ? 4   LEU N CD1 1 
ATOM   5117 C  CD2 . LEU D 4 26  ? 124.413 124.056 177.311 1.00 37.14  ? 4   LEU N CD2 1 
ATOM   5118 N  N   . GLN D 4 27  ? 124.049 123.280 182.566 1.00 33.29  ? 5   GLN N N   1 
ATOM   5119 C  CA  . GLN D 4 27  ? 124.195 122.560 183.826 1.00 34.38  ? 5   GLN N CA  1 
ATOM   5120 C  C   . GLN D 4 27  ? 123.733 121.125 183.641 1.00 36.84  ? 5   GLN N C   1 
ATOM   5121 O  O   . GLN D 4 27  ? 122.587 120.886 183.251 1.00 39.23  ? 5   GLN N O   1 
ATOM   5122 C  CB  . GLN D 4 27  ? 123.404 123.238 184.944 1.00 37.65  ? 5   GLN N CB  1 
ATOM   5123 C  CG  . GLN D 4 27  ? 124.218 124.229 185.752 1.00 40.37  ? 5   GLN N CG  1 
ATOM   5124 C  CD  . GLN D 4 27  ? 123.354 125.191 186.536 1.00 45.36  ? 5   GLN N CD  1 
ATOM   5125 O  OE1 . GLN D 4 27  ? 122.165 125.343 186.260 1.00 45.53  ? 5   GLN N OE1 1 
ATOM   5126 N  NE2 . GLN D 4 27  ? 123.947 125.846 187.525 1.00 47.55  ? 5   GLN N NE2 1 
ATOM   5127 N  N   . GLU D 4 28  ? 124.615 120.177 183.939 1.00 39.27  ? 6   GLU N N   1 
ATOM   5128 C  CA  . GLU D 4 28  ? 124.343 118.762 183.744 1.00 36.72  ? 6   GLU N CA  1 
ATOM   5129 C  C   . GLU D 4 28  ? 123.929 118.103 185.051 1.00 43.21  ? 6   GLU N C   1 
ATOM   5130 O  O   . GLU D 4 28  ? 124.391 118.471 186.133 1.00 49.07  ? 6   GLU N O   1 
ATOM   5131 C  CB  . GLU D 4 28  ? 125.566 118.046 183.177 1.00 37.70  ? 6   GLU N CB  1 
ATOM   5132 C  CG  . GLU D 4 28  ? 125.951 118.495 181.792 1.00 40.70  ? 6   GLU N CG  1 
ATOM   5133 C  CD  . GLU D 4 28  ? 126.864 119.689 181.820 1.00 42.25  ? 6   GLU N CD  1 
ATOM   5134 O  OE1 . GLU D 4 28  ? 127.237 120.123 182.925 1.00 46.33  ? 6   GLU N OE1 1 
ATOM   5135 O  OE2 . GLU D 4 28  ? 127.206 120.201 180.739 1.00 45.81  ? 6   GLU N OE2 1 
ATOM   5136 N  N   . SER D 4 29  ? 123.048 117.115 184.933 1.00 42.88  ? 7   SER N N   1 
ATOM   5137 C  CA  . SER D 4 29  ? 122.575 116.335 186.064 1.00 46.65  ? 7   SER N CA  1 
ATOM   5138 C  C   . SER D 4 29  ? 122.438 114.883 185.634 1.00 49.56  ? 7   SER N C   1 
ATOM   5139 O  O   . SER D 4 29  ? 122.400 114.565 184.443 1.00 46.42  ? 7   SER N O   1 
ATOM   5140 C  CB  . SER D 4 29  ? 121.241 116.865 186.599 1.00 46.16  ? 7   SER N CB  1 
ATOM   5141 O  OG  . SER D 4 29  ? 120.217 116.734 185.631 1.00 52.26  ? 7   SER N OG  1 
ATOM   5142 N  N   . GLY D 4 30  ? 122.370 114.004 186.618 1.00 56.42  ? 8   GLY N N   1 
ATOM   5143 C  CA  . GLY D 4 30  ? 122.349 112.577 186.346 1.00 55.17  ? 8   GLY N CA  1 
ATOM   5144 C  C   . GLY D 4 30  ? 123.743 111.987 186.325 1.00 57.77  ? 8   GLY N C   1 
ATOM   5145 O  O   . GLY D 4 30  ? 124.725 112.640 185.977 1.00 62.08  ? 8   GLY N O   1 
ATOM   5146 N  N   . GLY D 4 31  ? 123.831 110.724 186.716 1.00 59.83  ? 9   GLY N N   1 
ATOM   5147 C  CA  . GLY D 4 31  ? 125.097 110.033 186.760 1.00 60.64  ? 9   GLY N CA  1 
ATOM   5148 C  C   . GLY D 4 31  ? 125.289 109.338 188.083 1.00 64.08  ? 9   GLY N C   1 
ATOM   5149 O  O   . GLY D 4 31  ? 124.365 109.217 188.894 1.00 65.45  ? 9   GLY N O   1 
ATOM   5150 N  N   . GLY D 4 32  ? 126.511 108.868 188.311 1.00 66.32  ? 10  GLY N N   1 
ATOM   5151 C  CA  . GLY D 4 32  ? 126.820 108.140 189.523 1.00 66.40  ? 10  GLY N CA  1 
ATOM   5152 C  C   . GLY D 4 32  ? 127.510 106.817 189.265 1.00 69.05  ? 10  GLY N C   1 
ATOM   5153 O  O   . GLY D 4 32  ? 128.151 106.634 188.227 1.00 67.99  ? 10  GLY N O   1 
ATOM   5154 N  N   . LEU D 4 33  ? 127.380 105.884 190.202 1.00 73.32  ? 11  LEU N N   1 
ATOM   5155 C  CA  . LEU D 4 33  ? 128.053 104.594 190.141 1.00 72.79  ? 11  LEU N CA  1 
ATOM   5156 C  C   . LEU D 4 33  ? 127.047 103.511 189.779 1.00 74.83  ? 11  LEU N C   1 
ATOM   5157 O  O   . LEU D 4 33  ? 125.984 103.414 190.400 1.00 77.31  ? 11  LEU N O   1 
ATOM   5158 C  CB  . LEU D 4 33  ? 128.724 104.274 191.476 1.00 73.36  ? 11  LEU N CB  1 
ATOM   5159 C  CG  . LEU D 4 33  ? 129.223 102.848 191.686 1.00 74.70  ? 11  LEU N CG  1 
ATOM   5160 C  CD1 . LEU D 4 33  ? 130.677 102.727 191.271 1.00 73.59  ? 11  LEU N CD1 1 
ATOM   5161 C  CD2 . LEU D 4 33  ? 129.046 102.446 193.139 1.00 73.78  ? 11  LEU N CD2 1 
ATOM   5162 N  N   . VAL D 4 34  ? 127.381 102.704 188.770 1.00 75.52  ? 12  VAL N N   1 
ATOM   5163 C  CA  . VAL D 4 34  ? 126.516 101.626 188.312 1.00 75.95  ? 12  VAL N CA  1 
ATOM   5164 C  C   . VAL D 4 34  ? 127.350 100.379 188.056 1.00 77.31  ? 12  VAL N C   1 
ATOM   5165 O  O   . VAL D 4 34  ? 128.557 100.443 187.820 1.00 78.29  ? 12  VAL N O   1 
ATOM   5166 C  CB  . VAL D 4 34  ? 125.734 102.000 187.034 1.00 76.50  ? 12  VAL N CB  1 
ATOM   5167 C  CG1 . VAL D 4 34  ? 124.500 102.806 187.386 1.00 77.82  ? 12  VAL N CG1 1 
ATOM   5168 C  CG2 . VAL D 4 34  ? 126.622 102.767 186.079 1.00 76.35  ? 12  VAL N CG2 1 
ATOM   5169 N  N   . GLN D 4 35  ? 126.682 99.233  188.111 1.00 85.75  ? 13  GLN N N   1 
ATOM   5170 C  CA  . GLN D 4 35  ? 127.293 97.975  187.728 1.00 85.57  ? 13  GLN N CA  1 
ATOM   5171 C  C   . GLN D 4 35  ? 127.261 97.827  186.213 1.00 87.87  ? 13  GLN N C   1 
ATOM   5172 O  O   . GLN D 4 35  ? 126.451 98.466  185.537 1.00 88.94  ? 13  GLN N O   1 
ATOM   5173 C  CB  . GLN D 4 35  ? 126.562 96.814  188.392 1.00 85.31  ? 13  GLN N CB  1 
ATOM   5174 C  CG  . GLN D 4 35  ? 126.592 96.853  189.908 1.00 87.64  ? 13  GLN N CG  1 
ATOM   5175 C  CD  . GLN D 4 35  ? 127.989 96.678  190.466 1.00 89.32  ? 13  GLN N CD  1 
ATOM   5176 O  OE1 . GLN D 4 35  ? 128.565 95.593  190.400 1.00 89.15  ? 13  GLN N OE1 1 
ATOM   5177 N  NE2 . GLN D 4 35  ? 128.543 97.750  191.020 1.00 88.13  ? 13  GLN N NE2 1 
ATOM   5178 N  N   . PRO D 4 36  ? 128.149 97.012  185.646 1.00 88.10  ? 14  PRO N N   1 
ATOM   5179 C  CA  . PRO D 4 36  ? 128.110 96.790  184.197 1.00 86.91  ? 14  PRO N CA  1 
ATOM   5180 C  C   . PRO D 4 36  ? 126.767 96.224  183.763 1.00 86.46  ? 14  PRO N C   1 
ATOM   5181 O  O   . PRO D 4 36  ? 126.174 95.386  184.443 1.00 86.24  ? 14  PRO N O   1 
ATOM   5182 C  CB  . PRO D 4 36  ? 129.252 95.795  183.953 1.00 86.21  ? 14  PRO N CB  1 
ATOM   5183 C  CG  . PRO D 4 36  ? 129.698 95.339  185.302 1.00 88.40  ? 14  PRO N CG  1 
ATOM   5184 C  CD  . PRO D 4 36  ? 129.340 96.410  186.264 1.00 86.61  ? 14  PRO N CD  1 
ATOM   5185 N  N   . GLY D 4 37  ? 126.289 96.698  182.616 1.00 80.76  ? 15  GLY N N   1 
ATOM   5186 C  CA  . GLY D 4 37  ? 124.976 96.350  182.125 1.00 79.61  ? 15  GLY N CA  1 
ATOM   5187 C  C   . GLY D 4 37  ? 123.863 97.276  182.559 1.00 81.47  ? 15  GLY N C   1 
ATOM   5188 O  O   . GLY D 4 37  ? 122.721 97.086  182.125 1.00 82.17  ? 15  GLY N O   1 
ATOM   5189 N  N   . GLY D 4 38  ? 124.155 98.274  183.396 1.00 77.10  ? 16  GLY N N   1 
ATOM   5190 C  CA  . GLY D 4 38  ? 123.130 99.169  183.891 1.00 75.64  ? 16  GLY N CA  1 
ATOM   5191 C  C   . GLY D 4 38  ? 122.812 100.308 182.941 1.00 72.26  ? 16  GLY N C   1 
ATOM   5192 O  O   . GLY D 4 38  ? 123.496 100.545 181.949 1.00 71.27  ? 16  GLY N O   1 
ATOM   5193 N  N   . SER D 4 39  ? 121.749 101.035 183.273 1.00 61.69  ? 17  SER N N   1 
ATOM   5194 C  CA  . SER D 4 39  ? 121.236 102.112 182.440 1.00 61.12  ? 17  SER N CA  1 
ATOM   5195 C  C   . SER D 4 39  ? 121.178 103.414 183.226 1.00 62.14  ? 17  SER N C   1 
ATOM   5196 O  O   . SER D 4 39  ? 120.756 103.436 184.387 1.00 63.85  ? 17  SER N O   1 
ATOM   5197 C  CB  . SER D 4 39  ? 119.846 101.773 181.895 1.00 61.92  ? 17  SER N CB  1 
ATOM   5198 O  OG  . SER D 4 39  ? 119.850 100.521 181.231 1.00 64.73  ? 17  SER N OG  1 
ATOM   5199 N  N   . LEU D 4 40  ? 121.594 104.497 182.574 1.00 53.47  ? 18  LEU N N   1 
ATOM   5200 C  CA  . LEU D 4 40  ? 121.617 105.832 183.146 1.00 46.42  ? 18  LEU N CA  1 
ATOM   5201 C  C   . LEU D 4 40  ? 121.044 106.802 182.126 1.00 49.53  ? 18  LEU N C   1 
ATOM   5202 O  O   . LEU D 4 40  ? 120.943 106.492 180.938 1.00 55.28  ? 18  LEU N O   1 
ATOM   5203 C  CB  . LEU D 4 40  ? 123.037 106.250 183.529 1.00 45.66  ? 18  LEU N CB  1 
ATOM   5204 C  CG  . LEU D 4 40  ? 123.736 105.471 184.635 1.00 50.56  ? 18  LEU N CG  1 
ATOM   5205 C  CD1 . LEU D 4 40  ? 125.173 105.922 184.779 1.00 50.37  ? 18  LEU N CD1 1 
ATOM   5206 C  CD2 . LEU D 4 40  ? 122.981 105.655 185.936 1.00 50.20  ? 18  LEU N CD2 1 
ATOM   5207 N  N   . ARG D 4 41  ? 120.662 107.986 182.599 1.00 45.47  ? 19  ARG N N   1 
ATOM   5208 C  CA  . ARG D 4 41  ? 120.116 109.020 181.721 1.00 44.21  ? 19  ARG N CA  1 
ATOM   5209 C  C   . ARG D 4 41  ? 120.699 110.364 182.145 1.00 46.70  ? 19  ARG N C   1 
ATOM   5210 O  O   . ARG D 4 41  ? 120.244 110.962 183.123 1.00 50.35  ? 19  ARG N O   1 
ATOM   5211 C  CB  . ARG D 4 41  ? 118.595 109.042 181.764 1.00 38.59  ? 19  ARG N CB  1 
ATOM   5212 C  CG  . ARG D 4 41  ? 117.976 109.650 180.528 1.00 38.44  ? 19  ARG N CG  1 
ATOM   5213 C  CD  . ARG D 4 41  ? 116.540 110.054 180.758 1.00 40.30  ? 19  ARG N CD  1 
ATOM   5214 N  NE  . ARG D 4 41  ? 116.021 110.832 179.641 1.00 42.32  ? 19  ARG N NE  1 
ATOM   5215 C  CZ  . ARG D 4 41  ? 115.139 110.383 178.760 1.00 45.06  ? 19  ARG N CZ  1 
ATOM   5216 N  NH1 . ARG D 4 41  ? 114.645 109.160 178.840 1.00 46.95  ? 19  ARG N NH1 1 
ATOM   5217 N  NH2 . ARG D 4 41  ? 114.741 111.181 177.775 1.00 39.61  ? 19  ARG N NH2 1 
ATOM   5218 N  N   . LEU D 4 42  ? 121.697 110.834 181.403 1.00 37.01  ? 20  LEU N N   1 
ATOM   5219 C  CA  . LEU D 4 42  ? 122.273 112.144 181.659 1.00 36.39  ? 20  LEU N CA  1 
ATOM   5220 C  C   . LEU D 4 42  ? 121.394 113.224 181.052 1.00 38.51  ? 20  LEU N C   1 
ATOM   5221 O  O   . LEU D 4 42  ? 120.866 113.060 179.951 1.00 38.02  ? 20  LEU N O   1 
ATOM   5222 C  CB  . LEU D 4 42  ? 123.682 112.237 181.077 1.00 36.93  ? 20  LEU N CB  1 
ATOM   5223 C  CG  . LEU D 4 42  ? 124.649 111.091 181.352 1.00 36.26  ? 20  LEU N CG  1 
ATOM   5224 C  CD1 . LEU D 4 42  ? 126.005 111.392 180.757 1.00 33.70  ? 20  LEU N CD1 1 
ATOM   5225 C  CD2 . LEU D 4 42  ? 124.767 110.827 182.836 1.00 36.63  ? 20  LEU N CD2 1 
ATOM   5226 N  N   . SER D 4 43  ? 121.246 114.336 181.772 1.00 40.43  ? 21  SER N N   1 
ATOM   5227 C  CA  . SER D 4 43  ? 120.449 115.469 181.328 1.00 42.05  ? 21  SER N CA  1 
ATOM   5228 C  C   . SER D 4 43  ? 121.290 116.733 181.397 1.00 40.53  ? 21  SER N C   1 
ATOM   5229 O  O   . SER D 4 43  ? 122.205 116.837 182.213 1.00 44.56  ? 21  SER N O   1 
ATOM   5230 C  CB  . SER D 4 43  ? 119.189 115.630 182.183 1.00 38.94  ? 21  SER N CB  1 
ATOM   5231 O  OG  . SER D 4 43  ? 118.468 116.788 181.818 1.00 38.57  ? 21  SER N OG  1 
ATOM   5232 N  N   . CYS D 4 44  ? 120.979 117.694 180.531 1.00 29.80  ? 22  CYS N N   1 
ATOM   5233 C  CA  . CYS D 4 44  ? 121.721 118.952 180.458 1.00 27.63  ? 22  CYS N CA  1 
ATOM   5234 C  C   . CYS D 4 44  ? 120.721 120.067 180.209 1.00 29.19  ? 22  CYS N C   1 
ATOM   5235 O  O   . CYS D 4 44  ? 120.080 120.095 179.155 1.00 32.61  ? 22  CYS N O   1 
ATOM   5236 C  CB  . CYS D 4 44  ? 122.783 118.901 179.357 1.00 35.19  ? 22  CYS N CB  1 
ATOM   5237 S  SG  . CYS D 4 44  ? 123.860 120.340 179.170 1.00 46.40  ? 22  CYS N SG  1 
ATOM   5238 N  N   . ALA D 4 45  ? 120.578 120.969 181.177 1.00 38.12  ? 23  ALA N N   1 
ATOM   5239 C  CA  . ALA D 4 45  ? 119.652 122.091 181.094 1.00 34.48  ? 23  ALA N CA  1 
ATOM   5240 C  C   . ALA D 4 45  ? 120.418 123.353 180.730 1.00 33.17  ? 23  ALA N C   1 
ATOM   5241 O  O   . ALA D 4 45  ? 121.418 123.685 181.372 1.00 34.71  ? 23  ALA N O   1 
ATOM   5242 C  CB  . ALA D 4 45  ? 118.910 122.289 182.415 1.00 33.19  ? 23  ALA N CB  1 
ATOM   5243 N  N   . ALA D 4 46  ? 119.943 124.054 179.708 1.00 33.10  ? 24  ALA N N   1 
ATOM   5244 C  CA  . ALA D 4 46  ? 120.651 125.185 179.133 1.00 35.15  ? 24  ALA N CA  1 
ATOM   5245 C  C   . ALA D 4 46  ? 119.838 126.458 179.305 1.00 39.86  ? 24  ALA N C   1 
ATOM   5246 O  O   . ALA D 4 46  ? 118.607 126.434 179.230 1.00 42.74  ? 24  ALA N O   1 
ATOM   5247 C  CB  . ALA D 4 46  ? 120.935 124.950 177.653 1.00 37.76  ? 24  ALA N CB  1 
ATOM   5248 N  N   . SER D 4 47  ? 120.534 127.569 179.533 1.00 38.39  ? 25  SER N N   1 
ATOM   5249 C  CA  . SER D 4 47  ? 119.892 128.867 179.648 1.00 38.71  ? 25  SER N CA  1 
ATOM   5250 C  C   . SER D 4 47  ? 120.861 129.937 179.172 1.00 43.15  ? 25  SER N C   1 
ATOM   5251 O  O   . SER D 4 47  ? 122.073 129.717 179.094 1.00 46.02  ? 25  SER N O   1 
ATOM   5252 C  CB  . SER D 4 47  ? 119.437 129.148 181.082 1.00 40.01  ? 25  SER N CB  1 
ATOM   5253 O  OG  . SER D 4 47  ? 120.545 129.342 181.939 1.00 43.39  ? 25  SER N OG  1 
ATOM   5254 N  N   . GLY D 4 48  ? 120.309 131.101 178.842 1.00 35.34  ? 26  GLY N N   1 
ATOM   5255 C  CA  . GLY D 4 48  ? 121.092 132.226 178.386 1.00 29.63  ? 26  GLY N CA  1 
ATOM   5256 C  C   . GLY D 4 48  ? 121.207 132.375 176.886 1.00 34.84  ? 26  GLY N C   1 
ATOM   5257 O  O   . GLY D 4 48  ? 121.935 133.262 176.429 1.00 37.98  ? 26  GLY N O   1 
ATOM   5258 N  N   . PHE D 4 49  ? 120.518 131.544 176.109 1.00 32.52  ? 27  PHE N N   1 
ATOM   5259 C  CA  . PHE D 4 49  ? 120.587 131.611 174.655 1.00 23.96  ? 27  PHE N CA  1 
ATOM   5260 C  C   . PHE D 4 49  ? 119.370 130.900 174.077 1.00 24.05  ? 27  PHE N C   1 
ATOM   5261 O  O   . PHE D 4 49  ? 118.601 130.258 174.793 1.00 28.06  ? 27  PHE N O   1 
ATOM   5262 C  CB  . PHE D 4 49  ? 121.903 131.019 174.123 1.00 18.09  ? 27  PHE N CB  1 
ATOM   5263 C  CG  . PHE D 4 49  ? 122.072 129.552 174.390 1.00 30.74  ? 27  PHE N CG  1 
ATOM   5264 C  CD1 . PHE D 4 49  ? 122.400 129.093 175.649 1.00 34.72  ? 27  PHE N CD1 1 
ATOM   5265 C  CD2 . PHE D 4 49  ? 121.917 128.633 173.377 1.00 28.85  ? 27  PHE N CD2 1 
ATOM   5266 C  CE1 . PHE D 4 49  ? 122.552 127.753 175.889 1.00 26.83  ? 27  PHE N CE1 1 
ATOM   5267 C  CE2 . PHE D 4 49  ? 122.069 127.294 173.617 1.00 25.56  ? 27  PHE N CE2 1 
ATOM   5268 C  CZ  . PHE D 4 49  ? 122.388 126.855 174.871 1.00 23.07  ? 27  PHE N CZ  1 
ATOM   5269 N  N   . THR D 4 50  ? 119.196 131.042 172.765 1.00 28.78  ? 28  THR N N   1 
ATOM   5270 C  CA  . THR D 4 50  ? 118.080 130.429 172.051 1.00 28.58  ? 28  THR N CA  1 
ATOM   5271 C  C   . THR D 4 50  ? 118.447 128.994 171.702 1.00 27.31  ? 28  THR N C   1 
ATOM   5272 O  O   . THR D 4 50  ? 119.255 128.756 170.803 1.00 25.89  ? 28  THR N O   1 
ATOM   5273 C  CB  . THR D 4 50  ? 117.747 131.227 170.797 1.00 28.26  ? 28  THR N CB  1 
ATOM   5274 O  OG1 . THR D 4 50  ? 117.924 132.622 171.061 1.00 38.02  ? 28  THR N OG1 1 
ATOM   5275 C  CG2 . THR D 4 50  ? 116.309 130.983 170.377 1.00 23.97  ? 28  THR N CG2 1 
ATOM   5276 N  N   . PHE D 4 51  ? 117.830 128.039 172.399 1.00 28.30  ? 29  PHE N N   1 
ATOM   5277 C  CA  . PHE D 4 51  ? 118.273 126.650 172.346 1.00 24.12  ? 29  PHE N CA  1 
ATOM   5278 C  C   . PHE D 4 51  ? 118.153 126.052 170.950 1.00 27.49  ? 29  PHE N C   1 
ATOM   5279 O  O   . PHE D 4 51  ? 118.960 125.194 170.578 1.00 31.81  ? 29  PHE N O   1 
ATOM   5280 C  CB  . PHE D 4 51  ? 117.469 125.826 173.352 1.00 26.73  ? 29  PHE N CB  1 
ATOM   5281 C  CG  . PHE D 4 51  ? 118.024 124.457 173.608 1.00 29.55  ? 29  PHE N CG  1 
ATOM   5282 C  CD1 . PHE D 4 51  ? 119.230 124.294 174.250 1.00 33.39  ? 29  PHE N CD1 1 
ATOM   5283 C  CD2 . PHE D 4 51  ? 117.326 123.331 173.224 1.00 31.72  ? 29  PHE N CD2 1 
ATOM   5284 C  CE1 . PHE D 4 51  ? 119.731 123.037 174.487 1.00 35.27  ? 29  PHE N CE1 1 
ATOM   5285 C  CE2 . PHE D 4 51  ? 117.828 122.078 173.457 1.00 25.40  ? 29  PHE N CE2 1 
ATOM   5286 C  CZ  . PHE D 4 51  ? 119.029 121.931 174.089 1.00 26.51  ? 29  PHE N CZ  1 
ATOM   5287 N  N   . SER D 4 52  ? 117.174 126.495 170.162 1.00 22.53  ? 30  SER N N   1 
ATOM   5288 C  CA  . SER D 4 52  ? 116.818 125.828 168.916 1.00 18.70  ? 30  SER N CA  1 
ATOM   5289 C  C   . SER D 4 52  ? 117.584 126.321 167.696 1.00 13.17  ? 30  SER N C   1 
ATOM   5290 O  O   . SER D 4 52  ? 117.402 125.759 166.615 1.00 22.33  ? 30  SER N O   1 
ATOM   5291 C  CB  . SER D 4 52  ? 115.324 125.982 168.658 1.00 18.74  ? 30  SER N CB  1 
ATOM   5292 O  OG  . SER D 4 52  ? 114.597 125.800 169.854 1.00 21.70  ? 30  SER N OG  1 
ATOM   5293 N  N   . ASN D 4 53  ? 118.418 127.346 167.822 1.00 16.05  ? 31  ASN N N   1 
ATOM   5294 C  CA  . ASN D 4 53  ? 119.234 127.811 166.709 1.00 20.87  ? 31  ASN N CA  1 
ATOM   5295 C  C   . ASN D 4 53  ? 120.580 127.112 166.629 1.00 23.32  ? 31  ASN N C   1 
ATOM   5296 O  O   . ASN D 4 53  ? 121.328 127.355 165.679 1.00 23.67  ? 31  ASN N O   1 
ATOM   5297 C  CB  . ASN D 4 53  ? 119.476 129.320 166.803 1.00 23.62  ? 31  ASN N CB  1 
ATOM   5298 C  CG  . ASN D 4 53  ? 118.199 130.115 166.945 1.00 32.57  ? 31  ASN N CG  1 
ATOM   5299 O  OD1 . ASN D 4 53  ? 117.117 129.648 166.599 1.00 34.77  ? 31  ASN N OD1 1 
ATOM   5300 N  ND2 . ASN D 4 53  ? 118.321 131.332 167.450 1.00 29.57  ? 31  ASN N ND2 1 
ATOM   5301 N  N   . TYR D 4 54  ? 120.907 126.261 167.599 1.00 17.39  ? 32  TYR N N   1 
ATOM   5302 C  CA  . TYR D 4 54  ? 122.244 125.713 167.752 1.00 14.55  ? 32  TYR N CA  1 
ATOM   5303 C  C   . TYR D 4 54  ? 122.213 124.195 167.686 1.00 20.86  ? 32  TYR N C   1 
ATOM   5304 O  O   . TYR D 4 54  ? 121.200 123.563 167.993 1.00 22.16  ? 32  TYR N O   1 
ATOM   5305 C  CB  . TYR D 4 54  ? 122.873 126.136 169.087 1.00 17.25  ? 32  TYR N CB  1 
ATOM   5306 C  CG  . TYR D 4 54  ? 123.052 127.622 169.263 1.00 15.22  ? 32  TYR N CG  1 
ATOM   5307 C  CD1 . TYR D 4 54  ? 124.217 128.250 168.875 1.00 12.96  ? 32  TYR N CD1 1 
ATOM   5308 C  CD2 . TYR D 4 54  ? 122.058 128.391 169.835 1.00 12.21  ? 32  TYR N CD2 1 
ATOM   5309 C  CE1 . TYR D 4 54  ? 124.377 129.600 169.041 1.00 19.53  ? 32  TYR N CE1 1 
ATOM   5310 C  CE2 . TYR D 4 54  ? 122.209 129.739 170.000 1.00 10.52  ? 32  TYR N CE2 1 
ATOM   5311 C  CZ  . TYR D 4 54  ? 123.369 130.340 169.605 1.00 24.16  ? 32  TYR N CZ  1 
ATOM   5312 O  OH  . TYR D 4 54  ? 123.522 131.694 169.776 1.00 28.42  ? 32  TYR N OH  1 
ATOM   5313 N  N   . LYS D 4 55  ? 123.342 123.623 167.286 1.00 20.86  ? 33  LYS N N   1 
ATOM   5314 C  CA  . LYS D 4 55  ? 123.586 122.193 167.360 1.00 11.13  ? 33  LYS N CA  1 
ATOM   5315 C  C   . LYS D 4 55  ? 124.202 121.858 168.710 1.00 18.08  ? 33  LYS N C   1 
ATOM   5316 O  O   . LYS D 4 55  ? 124.950 122.654 169.278 1.00 24.09  ? 33  LYS N O   1 
ATOM   5317 C  CB  . LYS D 4 55  ? 124.512 121.761 166.225 1.00 18.42  ? 33  LYS N CB  1 
ATOM   5318 C  CG  . LYS D 4 55  ? 125.049 120.361 166.335 1.00 23.24  ? 33  LYS N CG  1 
ATOM   5319 C  CD  . LYS D 4 55  ? 126.278 120.180 165.491 1.00 24.52  ? 33  LYS N CD  1 
ATOM   5320 C  CE  . LYS D 4 55  ? 125.914 119.850 164.068 1.00 26.76  ? 33  LYS N CE  1 
ATOM   5321 N  NZ  . LYS D 4 55  ? 127.130 119.618 163.248 1.00 29.78  ? 33  LYS N NZ  1 
ATOM   5322 N  N   . MET D 4 56  ? 123.877 120.678 169.235 1.00 18.87  ? 34  MET N N   1 
ATOM   5323 C  CA  . MET D 4 56  ? 124.304 120.320 170.580 1.00 16.30  ? 34  MET N CA  1 
ATOM   5324 C  C   . MET D 4 56  ? 125.061 118.999 170.561 1.00 14.70  ? 34  MET N C   1 
ATOM   5325 O  O   . MET D 4 56  ? 124.811 118.139 169.716 1.00 31.74  ? 34  MET N O   1 
ATOM   5326 C  CB  . MET D 4 56  ? 123.108 120.235 171.529 1.00 21.14  ? 34  MET N CB  1 
ATOM   5327 C  CG  . MET D 4 56  ? 122.400 121.565 171.749 1.00 21.92  ? 34  MET N CG  1 
ATOM   5328 S  SD  . MET D 4 56  ? 123.241 122.707 172.851 1.00 27.92  ? 34  MET N SD  1 
ATOM   5329 C  CE  . MET D 4 56  ? 123.296 121.759 174.358 1.00 16.10  ? 34  MET N CE  1 
ATOM   5330 N  N   . ASN D 4 57  ? 126.007 118.844 171.486 1.00 13.22  ? 35  ASN N N   1 
ATOM   5331 C  CA  . ASN D 4 57  ? 126.891 117.688 171.484 1.00 11.25  ? 35  ASN N CA  1 
ATOM   5332 C  C   . ASN D 4 57  ? 127.075 117.154 172.895 1.00 12.18  ? 35  ASN N C   1 
ATOM   5333 O  O   . ASN D 4 57  ? 126.883 117.862 173.883 1.00 20.21  ? 35  ASN N O   1 
ATOM   5334 C  CB  . ASN D 4 57  ? 128.270 118.021 170.895 1.00 7.67   ? 35  ASN N CB  1 
ATOM   5335 C  CG  . ASN D 4 57  ? 128.203 119.046 169.797 1.00 16.55  ? 35  ASN N CG  1 
ATOM   5336 O  OD1 . ASN D 4 57  ? 127.568 118.831 168.774 1.00 23.22  ? 35  ASN N OD1 1 
ATOM   5337 N  ND2 . ASN D 4 57  ? 128.860 120.171 170.000 1.00 24.20  ? 35  ASN N ND2 1 
ATOM   5338 N  N   . TRP D 4 58  ? 127.466 115.886 172.964 1.00 18.43  ? 36  TRP N N   1 
ATOM   5339 C  CA  . TRP D 4 58  ? 127.923 115.236 174.184 1.00 12.79  ? 36  TRP N CA  1 
ATOM   5340 C  C   . TRP D 4 58  ? 129.384 114.866 174.005 1.00 14.96  ? 36  TRP N C   1 
ATOM   5341 O  O   . TRP D 4 58  ? 129.745 114.232 173.006 1.00 19.09  ? 36  TRP N O   1 
ATOM   5342 C  CB  . TRP D 4 58  ? 127.106 113.982 174.504 1.00 4.70   ? 36  TRP N CB  1 
ATOM   5343 C  CG  . TRP D 4 58  ? 125.825 114.256 175.189 1.00 5.01   ? 36  TRP N CG  1 
ATOM   5344 C  CD1 . TRP D 4 58  ? 124.594 114.249 174.632 1.00 16.20  ? 36  TRP N CD1 1 
ATOM   5345 C  CD2 . TRP D 4 58  ? 125.640 114.588 176.569 1.00 19.60  ? 36  TRP N CD2 1 
ATOM   5346 N  NE1 . TRP D 4 58  ? 123.648 114.556 175.570 1.00 19.68  ? 36  TRP N NE1 1 
ATOM   5347 C  CE2 . TRP D 4 58  ? 124.267 114.769 176.771 1.00 20.64  ? 36  TRP N CE2 1 
ATOM   5348 C  CE3 . TRP D 4 58  ? 126.504 114.750 177.652 1.00 25.08  ? 36  TRP N CE3 1 
ATOM   5349 C  CZ2 . TRP D 4 58  ? 123.734 115.101 178.009 1.00 19.80  ? 36  TRP N CZ2 1 
ATOM   5350 C  CZ3 . TRP D 4 58  ? 125.971 115.080 178.878 1.00 19.46  ? 36  TRP N CZ3 1 
ATOM   5351 C  CH2 . TRP D 4 58  ? 124.603 115.253 179.046 1.00 16.85  ? 36  TRP N CH2 1 
ATOM   5352 N  N   . VAL D 4 59  ? 130.205 115.253 174.980 1.00 25.10  ? 37  VAL N N   1 
ATOM   5353 C  CA  . VAL D 4 59  ? 131.650 115.086 174.970 1.00 26.84  ? 37  VAL N CA  1 
ATOM   5354 C  C   . VAL D 4 59  ? 132.020 114.415 176.285 1.00 27.41  ? 37  VAL N C   1 
ATOM   5355 O  O   . VAL D 4 59  ? 131.308 114.555 177.280 1.00 34.30  ? 37  VAL N O   1 
ATOM   5356 C  CB  . VAL D 4 59  ? 132.351 116.462 174.794 1.00 27.18  ? 37  VAL N CB  1 
ATOM   5357 C  CG1 . VAL D 4 59  ? 133.791 116.433 175.219 1.00 30.53  ? 37  VAL N CG1 1 
ATOM   5358 C  CG2 . VAL D 4 59  ? 132.243 116.936 173.359 1.00 20.97  ? 37  VAL N CG2 1 
ATOM   5359 N  N   . ARG D 4 60  ? 133.107 113.646 176.293 1.00 27.06  ? 38  ARG N N   1 
ATOM   5360 C  CA  . ARG D 4 60  ? 133.524 112.996 177.527 1.00 35.44  ? 38  ARG N CA  1 
ATOM   5361 C  C   . ARG D 4 60  ? 135.032 113.050 177.678 1.00 37.82  ? 38  ARG N C   1 
ATOM   5362 O  O   . ARG D 4 60  ? 135.772 113.089 176.695 1.00 40.87  ? 38  ARG N O   1 
ATOM   5363 C  CB  . ARG D 4 60  ? 133.064 111.537 177.603 1.00 40.13  ? 38  ARG N CB  1 
ATOM   5364 C  CG  . ARG D 4 60  ? 133.563 110.646 176.484 1.00 35.65  ? 38  ARG N CG  1 
ATOM   5365 C  CD  . ARG D 4 60  ? 133.132 109.216 176.711 1.00 39.22  ? 38  ARG N CD  1 
ATOM   5366 N  NE  . ARG D 4 60  ? 133.628 108.310 175.684 1.00 44.24  ? 38  ARG N NE  1 
ATOM   5367 C  CZ  . ARG D 4 60  ? 133.341 107.018 175.626 1.00 43.53  ? 38  ARG N CZ  1 
ATOM   5368 N  NH1 . ARG D 4 60  ? 132.567 106.441 176.529 1.00 40.21  ? 38  ARG N NH1 1 
ATOM   5369 N  NH2 . ARG D 4 60  ? 133.845 106.284 174.639 1.00 41.05  ? 38  ARG N NH2 1 
ATOM   5370 N  N   . GLN D 4 61  ? 135.473 113.050 178.932 1.00 43.59  ? 39  GLN N N   1 
ATOM   5371 C  CA  . GLN D 4 61  ? 136.885 113.031 179.299 1.00 45.66  ? 39  GLN N CA  1 
ATOM   5372 C  C   . GLN D 4 61  ? 137.119 111.853 180.231 1.00 50.03  ? 39  GLN N C   1 
ATOM   5373 O  O   . GLN D 4 61  ? 136.614 111.841 181.358 1.00 51.98  ? 39  GLN N O   1 
ATOM   5374 C  CB  . GLN D 4 61  ? 137.300 114.333 179.971 1.00 43.69  ? 39  GLN N CB  1 
ATOM   5375 C  CG  . GLN D 4 61  ? 138.784 114.440 180.200 1.00 48.16  ? 39  GLN N CG  1 
ATOM   5376 C  CD  . GLN D 4 61  ? 139.143 115.621 181.051 1.00 49.30  ? 39  GLN N CD  1 
ATOM   5377 O  OE1 . GLN D 4 61  ? 138.615 115.791 182.148 1.00 49.72  ? 39  GLN N OE1 1 
ATOM   5378 N  NE2 . GLN D 4 61  ? 140.043 116.455 180.552 1.00 48.05  ? 39  GLN N NE2 1 
ATOM   5379 N  N   . ALA D 4 62  ? 137.863 110.863 179.759 1.00 57.98  ? 40  ALA N N   1 
ATOM   5380 C  CA  . ALA D 4 62  ? 138.183 109.698 180.560 1.00 54.69  ? 40  ALA N CA  1 
ATOM   5381 C  C   . ALA D 4 62  ? 139.291 110.034 181.547 1.00 57.80  ? 40  ALA N C   1 
ATOM   5382 O  O   . ALA D 4 62  ? 140.059 110.972 181.330 1.00 59.58  ? 40  ALA N O   1 
ATOM   5383 C  CB  . ALA D 4 62  ? 138.602 108.548 179.654 1.00 54.31  ? 40  ALA N CB  1 
ATOM   5384 N  N   . PRO D 4 63  ? 139.397 109.293 182.653 1.00 67.34  ? 41  PRO N N   1 
ATOM   5385 C  CA  . PRO D 4 63  ? 140.490 109.546 183.602 1.00 68.59  ? 41  PRO N CA  1 
ATOM   5386 C  C   . PRO D 4 63  ? 141.805 109.009 183.060 1.00 68.12  ? 41  PRO N C   1 
ATOM   5387 O  O   . PRO D 4 63  ? 142.028 107.796 183.008 1.00 67.12  ? 41  PRO N O   1 
ATOM   5388 C  CB  . PRO D 4 63  ? 140.038 108.800 184.866 1.00 65.82  ? 41  PRO N CB  1 
ATOM   5389 C  CG  . PRO D 4 63  ? 138.931 107.910 184.468 1.00 66.91  ? 41  PRO N CG  1 
ATOM   5390 C  CD  . PRO D 4 63  ? 138.570 108.140 183.045 1.00 67.00  ? 41  PRO N CD  1 
ATOM   5391 N  N   . GLY D 4 64  ? 142.681 109.920 182.645 1.00 67.86  ? 42  GLY N N   1 
ATOM   5392 C  CA  . GLY D 4 64  ? 143.970 109.580 182.075 1.00 66.82  ? 42  GLY N CA  1 
ATOM   5393 C  C   . GLY D 4 64  ? 144.190 110.085 180.664 1.00 68.92  ? 42  GLY N C   1 
ATOM   5394 O  O   . GLY D 4 64  ? 145.347 110.211 180.240 1.00 69.69  ? 42  GLY N O   1 
ATOM   5395 N  N   . LYS D 4 65  ? 143.127 110.386 179.918 1.00 57.94  ? 43  LYS N N   1 
ATOM   5396 C  CA  . LYS D 4 65  ? 143.279 110.812 178.533 1.00 57.48  ? 43  LYS N CA  1 
ATOM   5397 C  C   . LYS D 4 65  ? 142.606 112.154 178.280 1.00 59.13  ? 43  LYS N C   1 
ATOM   5398 O  O   . LYS D 4 65  ? 142.167 112.822 179.221 1.00 60.34  ? 43  LYS N O   1 
ATOM   5399 C  CB  . LYS D 4 65  ? 142.721 109.754 177.580 1.00 55.77  ? 43  LYS N CB  1 
ATOM   5400 C  CG  . LYS D 4 65  ? 142.615 108.364 178.178 1.00 56.82  ? 43  LYS N CG  1 
ATOM   5401 C  CD  . LYS D 4 65  ? 141.465 107.584 177.566 1.00 58.27  ? 43  LYS N CD  1 
ATOM   5402 C  CE  . LYS D 4 65  ? 141.142 106.346 178.383 1.00 60.96  ? 43  LYS N CE  1 
ATOM   5403 N  NZ  . LYS D 4 65  ? 140.282 105.387 177.637 1.00 58.26  ? 43  LYS N NZ  1 
ATOM   5404 N  N   . GLY D 4 66  ? 142.532 112.561 177.011 1.00 47.06  ? 44  GLY N N   1 
ATOM   5405 C  CA  . GLY D 4 66  ? 141.967 113.843 176.650 1.00 41.92  ? 44  GLY N CA  1 
ATOM   5406 C  C   . GLY D 4 66  ? 140.475 113.775 176.380 1.00 40.36  ? 44  GLY N C   1 
ATOM   5407 O  O   . GLY D 4 66  ? 139.833 112.733 176.489 1.00 45.30  ? 44  GLY N O   1 
ATOM   5408 N  N   . LEU D 4 67  ? 139.921 114.930 176.026 1.00 30.83  ? 45  LEU N N   1 
ATOM   5409 C  CA  . LEU D 4 67  ? 138.498 115.020 175.746 1.00 29.24  ? 45  LEU N CA  1 
ATOM   5410 C  C   . LEU D 4 67  ? 138.165 114.289 174.456 1.00 33.27  ? 45  LEU N C   1 
ATOM   5411 O  O   . LEU D 4 67  ? 138.895 114.375 173.467 1.00 39.14  ? 45  LEU N O   1 
ATOM   5412 C  CB  . LEU D 4 67  ? 138.065 116.480 175.653 1.00 32.25  ? 45  LEU N CB  1 
ATOM   5413 C  CG  . LEU D 4 67  ? 137.950 117.222 176.981 1.00 31.11  ? 45  LEU N CG  1 
ATOM   5414 C  CD1 . LEU D 4 67  ? 138.543 118.597 176.850 1.00 29.25  ? 45  LEU N CD1 1 
ATOM   5415 C  CD2 . LEU D 4 67  ? 136.510 117.300 177.439 1.00 29.70  ? 45  LEU N CD2 1 
ATOM   5416 N  N   . GLU D 4 68  ? 137.050 113.568 174.469 1.00 36.71  ? 46  GLU N N   1 
ATOM   5417 C  CA  . GLU D 4 68  ? 136.635 112.735 173.354 1.00 32.22  ? 46  GLU N CA  1 
ATOM   5418 C  C   . GLU D 4 68  ? 135.194 113.053 172.998 1.00 29.83  ? 46  GLU N C   1 
ATOM   5419 O  O   . GLU D 4 68  ? 134.357 113.235 173.883 1.00 34.89  ? 46  GLU N O   1 
ATOM   5420 C  CB  . GLU D 4 68  ? 136.776 111.252 173.696 1.00 30.36  ? 46  GLU N CB  1 
ATOM   5421 C  CG  . GLU D 4 68  ? 137.242 110.382 172.550 1.00 34.97  ? 46  GLU N CG  1 
ATOM   5422 C  CD  . GLU D 4 68  ? 136.737 108.956 172.657 1.00 42.21  ? 46  GLU N CD  1 
ATOM   5423 O  OE1 . GLU D 4 68  ? 137.028 108.297 173.675 1.00 40.70  ? 46  GLU N OE1 1 
ATOM   5424 O  OE2 . GLU D 4 68  ? 136.054 108.493 171.722 1.00 38.92  ? 46  GLU N OE2 1 
ATOM   5425 N  N   . TRP D 4 69  ? 134.916 113.118 171.702 1.00 18.72  ? 47  TRP N N   1 
ATOM   5426 C  CA  . TRP D 4 69  ? 133.580 113.411 171.207 1.00 13.01  ? 47  TRP N CA  1 
ATOM   5427 C  C   . TRP D 4 69  ? 132.723 112.157 171.247 1.00 25.49  ? 47  TRP N C   1 
ATOM   5428 O  O   . TRP D 4 69  ? 133.167 111.078 170.850 1.00 30.12  ? 47  TRP N O   1 
ATOM   5429 C  CB  . TRP D 4 69  ? 133.669 113.952 169.783 1.00 15.66  ? 47  TRP N CB  1 
ATOM   5430 C  CG  . TRP D 4 69  ? 132.371 114.179 169.095 1.00 13.13  ? 47  TRP N CG  1 
ATOM   5431 C  CD1 . TRP D 4 69  ? 131.565 115.260 169.217 1.00 16.74  ? 47  TRP N CD1 1 
ATOM   5432 C  CD2 . TRP D 4 69  ? 131.748 113.319 168.136 1.00 21.48  ? 47  TRP N CD2 1 
ATOM   5433 N  NE1 . TRP D 4 69  ? 130.468 115.124 168.414 1.00 22.01  ? 47  TRP N NE1 1 
ATOM   5434 C  CE2 . TRP D 4 69  ? 130.558 113.937 167.739 1.00 22.43  ? 47  TRP N CE2 1 
ATOM   5435 C  CE3 . TRP D 4 69  ? 132.076 112.080 167.586 1.00 20.26  ? 47  TRP N CE3 1 
ATOM   5436 C  CZ2 . TRP D 4 69  ? 129.698 113.361 166.819 1.00 18.83  ? 47  TRP N CZ2 1 
ATOM   5437 C  CZ3 . TRP D 4 69  ? 131.221 111.515 166.680 1.00 14.90  ? 47  TRP N CZ3 1 
ATOM   5438 C  CH2 . TRP D 4 69  ? 130.050 112.152 166.304 1.00 14.58  ? 47  TRP N CH2 1 
ATOM   5439 N  N   . VAL D 4 70  ? 131.492 112.298 171.731 1.00 22.40  ? 48  VAL N N   1 
ATOM   5440 C  CA  . VAL D 4 70  ? 130.574 111.174 171.890 1.00 9.72   ? 48  VAL N CA  1 
ATOM   5441 C  C   . VAL D 4 70  ? 129.430 111.241 170.884 1.00 8.15   ? 48  VAL N C   1 
ATOM   5442 O  O   . VAL D 4 70  ? 129.219 110.308 170.113 1.00 15.32  ? 48  VAL N O   1 
ATOM   5443 C  CB  . VAL D 4 70  ? 130.046 111.081 173.340 1.00 14.24  ? 48  VAL N CB  1 
ATOM   5444 C  CG1 . VAL D 4 70  ? 128.794 110.237 173.400 1.00 15.37  ? 48  VAL N CG1 1 
ATOM   5445 C  CG2 . VAL D 4 70  ? 131.100 110.500 174.246 1.00 17.11  ? 48  VAL N CG2 1 
ATOM   5446 N  N   . SER D 4 71  ? 128.682 112.339 170.870 1.00 19.73  ? 49  SER N N   1 
ATOM   5447 C  CA  . SER D 4 71  ? 127.476 112.347 170.046 1.00 11.47  ? 49  SER N CA  1 
ATOM   5448 C  C   . SER D 4 71  ? 127.103 113.773 169.686 1.00 14.37  ? 49  SER N C   1 
ATOM   5449 O  O   . SER D 4 71  ? 127.532 114.721 170.338 1.00 24.22  ? 49  SER N O   1 
ATOM   5450 C  CB  . SER D 4 71  ? 126.315 111.658 170.768 1.00 12.51  ? 49  SER N CB  1 
ATOM   5451 O  OG  . SER D 4 71  ? 125.262 111.350 169.879 1.00 20.91  ? 49  SER N OG  1 
ATOM   5452 N  N   . ASP D 4 72  ? 126.283 113.916 168.646 1.00 17.70  ? 50  ASP N N   1 
ATOM   5453 C  CA  . ASP D 4 72  ? 125.761 115.234 168.304 1.00 14.27  ? 50  ASP N CA  1 
ATOM   5454 C  C   . ASP D 4 72  ? 124.362 115.126 167.719 1.00 11.05  ? 50  ASP N C   1 
ATOM   5455 O  O   . ASP D 4 72  ? 124.003 114.118 167.107 1.00 30.36  ? 50  ASP N O   1 
ATOM   5456 C  CB  . ASP D 4 72  ? 126.718 115.991 167.365 1.00 15.40  ? 50  ASP N CB  1 
ATOM   5457 C  CG  . ASP D 4 72  ? 126.881 115.346 165.999 1.00 29.04  ? 50  ASP N CG  1 
ATOM   5458 O  OD1 . ASP D 4 72  ? 126.152 114.397 165.651 1.00 35.38  ? 50  ASP N OD1 1 
ATOM   5459 O  OD2 . ASP D 4 72  ? 127.756 115.813 165.244 1.00 33.40  ? 50  ASP N OD2 1 
ATOM   5460 N  N   . ILE D 4 73  ? 123.581 116.187 167.923 1.00 8.40   ? 51  ILE N N   1 
ATOM   5461 C  CA  . ILE D 4 73  ? 122.219 116.300 167.411 1.00 11.32  ? 51  ILE N CA  1 
ATOM   5462 C  C   . ILE D 4 73  ? 122.001 117.718 166.890 1.00 18.19  ? 51  ILE N C   1 
ATOM   5463 O  O   . ILE D 4 73  ? 122.512 118.694 167.454 1.00 21.73  ? 51  ILE N O   1 
ATOM   5464 C  CB  . ILE D 4 73  ? 121.168 115.920 168.479 1.00 18.29  ? 51  ILE N CB  1 
ATOM   5465 C  CG1 . ILE D 4 73  ? 119.821 115.619 167.832 1.00 16.78  ? 51  ILE N CG1 1 
ATOM   5466 C  CG2 . ILE D 4 73  ? 121.005 117.007 169.518 1.00 24.74  ? 51  ILE N CG2 1 
ATOM   5467 C  CD1 . ILE D 4 73  ? 118.795 115.132 168.807 1.00 23.95  ? 51  ILE N CD1 1 
ATOM   5468 N  N   . SER D 4 74  ? 121.239 117.823 165.806 1.00 20.69  ? 52  SER N N   1 
ATOM   5469 C  CA  . SER D 4 74  ? 121.097 119.056 165.048 1.00 22.59  ? 52  SER N CA  1 
ATOM   5470 C  C   . SER D 4 74  ? 120.054 119.967 165.689 1.00 33.74  ? 52  SER N C   1 
ATOM   5471 O  O   . SER D 4 74  ? 119.610 119.750 166.818 1.00 43.68  ? 52  SER N O   1 
ATOM   5472 C  CB  . SER D 4 74  ? 120.746 118.737 163.602 1.00 25.33  ? 52  SER N CB  1 
ATOM   5473 O  OG  . SER D 4 74  ? 120.937 119.870 162.778 1.00 35.75  ? 52  SER N OG  1 
ATOM   5474 N  N   . GLN D 4 75  ? 119.655 121.013 164.958 1.00 27.15  ? 53  GLN N N   1 
ATOM   5475 C  CA  . GLN D 4 75  ? 118.761 122.032 165.505 1.00 21.72  ? 53  GLN N CA  1 
ATOM   5476 C  C   . GLN D 4 75  ? 117.358 121.485 165.750 1.00 27.27  ? 53  GLN N C   1 
ATOM   5477 O  O   . GLN D 4 75  ? 116.689 121.881 166.710 1.00 24.62  ? 53  GLN N O   1 
ATOM   5478 C  CB  . GLN D 4 75  ? 118.709 123.229 164.559 1.00 20.96  ? 53  GLN N CB  1 
ATOM   5479 C  CG  . GLN D 4 75  ? 119.994 124.030 164.471 1.00 24.92  ? 53  GLN N CG  1 
ATOM   5480 C  CD  . GLN D 4 75  ? 121.076 123.362 163.640 1.00 26.81  ? 53  GLN N CD  1 
ATOM   5481 O  OE1 . GLN D 4 75  ? 121.230 122.144 163.658 1.00 21.41  ? 53  GLN N OE1 1 
ATOM   5482 N  NE2 . GLN D 4 75  ? 121.843 124.164 162.919 1.00 29.43  ? 53  GLN N NE2 1 
ATOM   5483 N  N   . SER D 4 76  ? 116.888 120.590 164.888 1.00 33.99  ? 54  SER N N   1 
ATOM   5484 C  CA  . SER D 4 76  ? 115.556 120.023 165.031 1.00 35.39  ? 54  SER N CA  1 
ATOM   5485 C  C   . SER D 4 76  ? 115.559 118.619 165.613 1.00 36.54  ? 54  SER N C   1 
ATOM   5486 O  O   . SER D 4 76  ? 114.533 118.188 166.149 1.00 40.14  ? 54  SER N O   1 
ATOM   5487 C  CB  . SER D 4 76  ? 114.842 119.996 163.674 1.00 34.88  ? 54  SER N CB  1 
ATOM   5488 O  OG  . SER D 4 76  ? 115.510 119.140 162.764 1.00 34.73  ? 54  SER N OG  1 
ATOM   5489 N  N   . GLY D 4 77  ? 116.676 117.908 165.531 1.00 29.97  ? 55  GLY N N   1 
ATOM   5490 C  CA  . GLY D 4 77  ? 116.737 116.529 165.947 1.00 27.44  ? 55  GLY N CA  1 
ATOM   5491 C  C   . GLY D 4 77  ? 116.640 115.520 164.830 1.00 32.31  ? 55  GLY N C   1 
ATOM   5492 O  O   . GLY D 4 77  ? 116.542 114.322 165.112 1.00 34.19  ? 55  GLY N O   1 
ATOM   5493 N  N   . ALA D 4 78  ? 116.655 115.961 163.572 1.00 34.84  ? 56  ALA N N   1 
ATOM   5494 C  CA  . ALA D 4 78  ? 116.594 115.019 162.461 1.00 33.05  ? 56  ALA N CA  1 
ATOM   5495 C  C   . ALA D 4 78  ? 117.925 114.305 162.260 1.00 33.27  ? 56  ALA N C   1 
ATOM   5496 O  O   . ALA D 4 78  ? 117.953 113.098 162.001 1.00 36.36  ? 56  ALA N O   1 
ATOM   5497 C  CB  . ALA D 4 78  ? 116.172 115.743 161.185 1.00 30.45  ? 56  ALA N CB  1 
ATOM   5498 N  N   . SER D 4 79  ? 119.035 115.028 162.378 1.00 27.83  ? 57  SER N N   1 
ATOM   5499 C  CA  . SER D 4 79  ? 120.364 114.468 162.178 1.00 26.33  ? 57  SER N CA  1 
ATOM   5500 C  C   . SER D 4 79  ? 120.974 114.090 163.520 1.00 29.18  ? 57  SER N C   1 
ATOM   5501 O  O   . SER D 4 79  ? 121.002 114.903 164.445 1.00 38.16  ? 57  SER N O   1 
ATOM   5502 C  CB  . SER D 4 79  ? 121.269 115.462 161.454 1.00 24.04  ? 57  SER N CB  1 
ATOM   5503 O  OG  . SER D 4 79  ? 120.688 115.887 160.240 1.00 31.90  ? 57  SER N OG  1 
ATOM   5504 N  N   . ILE D 4 80  ? 121.458 112.857 163.620 1.00 23.62  ? 58  ILE N N   1 
ATOM   5505 C  CA  . ILE D 4 80  ? 122.058 112.329 164.837 1.00 17.12  ? 58  ILE N CA  1 
ATOM   5506 C  C   . ILE D 4 80  ? 123.340 111.608 164.457 1.00 21.54  ? 58  ILE N C   1 
ATOM   5507 O  O   . ILE D 4 80  ? 123.375 110.876 163.465 1.00 32.38  ? 58  ILE N O   1 
ATOM   5508 C  CB  . ILE D 4 80  ? 121.103 111.373 165.575 1.00 17.44  ? 58  ILE N CB  1 
ATOM   5509 C  CG1 . ILE D 4 80  ? 119.778 112.057 165.876 1.00 18.52  ? 58  ILE N CG1 1 
ATOM   5510 C  CG2 . ILE D 4 80  ? 121.718 110.910 166.850 1.00 22.39  ? 58  ILE N CG2 1 
ATOM   5511 C  CD1 . ILE D 4 80  ? 118.915 111.291 166.835 1.00 23.35  ? 58  ILE N CD1 1 
ATOM   5512 N  N   . SER D 4 81  ? 124.397 111.816 165.234 1.00 19.24  ? 59  SER N N   1 
ATOM   5513 C  CA  . SER D 4 81  ? 125.653 111.132 164.969 1.00 14.69  ? 59  SER N CA  1 
ATOM   5514 C  C   . SER D 4 81  ? 126.251 110.629 166.270 1.00 18.68  ? 59  SER N C   1 
ATOM   5515 O  O   . SER D 4 81  ? 126.173 111.307 167.297 1.00 24.47  ? 59  SER N O   1 
ATOM   5516 C  CB  . SER D 4 81  ? 126.650 112.043 164.260 1.00 18.68  ? 59  SER N CB  1 
ATOM   5517 O  OG  . SER D 4 81  ? 126.003 112.818 163.274 1.00 31.22  ? 59  SER N OG  1 
ATOM   5518 N  N   . TYR D 4 82  ? 126.856 109.444 166.209 1.00 20.51  ? 60  TYR N N   1 
ATOM   5519 C  CA  . TYR D 4 82  ? 127.482 108.804 167.353 1.00 20.30  ? 60  TYR N CA  1 
ATOM   5520 C  C   . TYR D 4 82  ? 128.919 108.446 167.020 1.00 20.02  ? 60  TYR N C   1 
ATOM   5521 O  O   . TYR D 4 82  ? 129.258 108.186 165.865 1.00 22.81  ? 60  TYR N O   1 
ATOM   5522 C  CB  . TYR D 4 82  ? 126.760 107.523 167.770 1.00 18.35  ? 60  TYR N CB  1 
ATOM   5523 C  CG  . TYR D 4 82  ? 125.301 107.684 168.091 1.00 23.45  ? 60  TYR N CG  1 
ATOM   5524 C  CD1 . TYR D 4 82  ? 124.346 107.606 167.098 1.00 25.44  ? 60  TYR N CD1 1 
ATOM   5525 C  CD2 . TYR D 4 82  ? 124.878 107.891 169.391 1.00 20.89  ? 60  TYR N CD2 1 
ATOM   5526 C  CE1 . TYR D 4 82  ? 123.016 107.741 167.383 1.00 24.23  ? 60  TYR N CE1 1 
ATOM   5527 C  CE2 . TYR D 4 82  ? 123.545 108.027 169.685 1.00 23.63  ? 60  TYR N CE2 1 
ATOM   5528 C  CZ  . TYR D 4 82  ? 122.618 107.950 168.675 1.00 27.06  ? 60  TYR N CZ  1 
ATOM   5529 O  OH  . TYR D 4 82  ? 121.281 108.083 168.954 1.00 26.22  ? 60  TYR N OH  1 
ATOM   5530 N  N   . THR D 4 83  ? 129.760 108.428 168.047 1.00 22.85  ? 61  THR N N   1 
ATOM   5531 C  CA  . THR D 4 83  ? 131.090 107.872 167.891 1.00 22.89  ? 61  THR N CA  1 
ATOM   5532 C  C   . THR D 4 83  ? 130.983 106.365 167.713 1.00 35.03  ? 61  THR N C   1 
ATOM   5533 O  O   . THR D 4 83  ? 129.937 105.761 167.956 1.00 41.22  ? 61  THR N O   1 
ATOM   5534 C  CB  . THR D 4 83  ? 131.968 108.218 169.093 1.00 26.96  ? 61  THR N CB  1 
ATOM   5535 O  OG1 . THR D 4 83  ? 133.345 108.174 168.711 1.00 28.10  ? 61  THR N OG1 1 
ATOM   5536 C  CG2 . THR D 4 83  ? 131.739 107.253 170.228 1.00 22.84  ? 61  THR N CG2 1 
ATOM   5537 N  N   . GLY D 4 84  ? 132.076 105.753 167.265 1.00 37.80  ? 62  GLY N N   1 
ATOM   5538 C  CA  . GLY D 4 84  ? 132.018 104.344 166.909 1.00 30.03  ? 62  GLY N CA  1 
ATOM   5539 C  C   . GLY D 4 84  ? 131.643 103.450 168.075 1.00 22.04  ? 62  GLY N C   1 
ATOM   5540 O  O   . GLY D 4 84  ? 130.765 102.596 167.959 1.00 24.08  ? 62  GLY N O   1 
ATOM   5541 N  N   . SER D 4 85  ? 132.290 103.649 169.222 1.00 17.97  ? 63  SER N N   1 
ATOM   5542 C  CA  . SER D 4 85  ? 132.162 102.695 170.316 1.00 24.73  ? 63  SER N CA  1 
ATOM   5543 C  C   . SER D 4 85  ? 130.794 102.722 170.983 1.00 32.96  ? 63  SER N C   1 
ATOM   5544 O  O   . SER D 4 85  ? 130.409 101.730 171.608 1.00 35.21  ? 63  SER N O   1 
ATOM   5545 C  CB  . SER D 4 85  ? 133.253 102.946 171.354 1.00 29.06  ? 63  SER N CB  1 
ATOM   5546 O  OG  . SER D 4 85  ? 133.478 104.331 171.532 1.00 39.94  ? 63  SER N OG  1 
ATOM   5547 N  N   . VAL D 4 86  ? 130.050 103.824 170.874 1.00 39.74  ? 64  VAL N N   1 
ATOM   5548 C  CA  . VAL D 4 86  ? 128.739 103.939 171.504 1.00 33.83  ? 64  VAL N CA  1 
ATOM   5549 C  C   . VAL D 4 86  ? 127.601 103.707 170.525 1.00 34.96  ? 64  VAL N C   1 
ATOM   5550 O  O   . VAL D 4 86  ? 126.434 103.700 170.935 1.00 35.34  ? 64  VAL N O   1 
ATOM   5551 C  CB  . VAL D 4 86  ? 128.578 105.312 172.184 1.00 31.10  ? 64  VAL N CB  1 
ATOM   5552 C  CG1 . VAL D 4 86  ? 129.794 105.630 173.024 1.00 29.26  ? 64  VAL N CG1 1 
ATOM   5553 C  CG2 . VAL D 4 86  ? 128.350 106.389 171.148 1.00 21.36  ? 64  VAL N CG2 1 
ATOM   5554 N  N   . LYS D 4 87  ? 127.906 103.512 169.244 1.00 34.46  ? 65  LYS N N   1 
ATOM   5555 C  CA  . LYS D 4 87  ? 126.900 103.314 168.208 1.00 29.35  ? 65  LYS N CA  1 
ATOM   5556 C  C   . LYS D 4 87  ? 126.086 102.056 168.467 1.00 34.26  ? 65  LYS N C   1 
ATOM   5557 O  O   . LYS D 4 87  ? 126.604 100.941 168.361 1.00 33.71  ? 65  LYS N O   1 
ATOM   5558 C  CB  . LYS D 4 87  ? 127.565 103.232 166.834 1.00 25.35  ? 65  LYS N CB  1 
ATOM   5559 C  CG  . LYS D 4 87  ? 126.614 103.379 165.669 1.00 28.54  ? 65  LYS N CG  1 
ATOM   5560 C  CD  . LYS D 4 87  ? 127.003 104.550 164.792 1.00 30.07  ? 65  LYS N CD  1 
ATOM   5561 C  CE  . LYS D 4 87  ? 128.342 104.316 164.123 1.00 25.34  ? 65  LYS N CE  1 
ATOM   5562 N  NZ  . LYS D 4 87  ? 128.783 105.501 163.349 1.00 30.82  ? 65  LYS N NZ  1 
ATOM   5563 N  N   . GLY D 4 88  ? 124.807 102.227 168.805 1.00 36.44  ? 66  GLY N N   1 
ATOM   5564 C  CA  . GLY D 4 88  ? 123.890 101.123 169.024 1.00 33.85  ? 66  GLY N CA  1 
ATOM   5565 C  C   . GLY D 4 88  ? 123.328 101.067 170.430 1.00 33.72  ? 66  GLY N C   1 
ATOM   5566 O  O   . GLY D 4 88  ? 122.248 100.505 170.634 1.00 33.30  ? 66  GLY N O   1 
ATOM   5567 N  N   . ARG D 4 89  ? 124.034 101.641 171.401 1.00 38.32  ? 67  ARG N N   1 
ATOM   5568 C  CA  . ARG D 4 89  ? 123.612 101.547 172.789 1.00 35.28  ? 67  ARG N CA  1 
ATOM   5569 C  C   . ARG D 4 89  ? 123.563 102.879 173.533 1.00 36.99  ? 67  ARG N C   1 
ATOM   5570 O  O   . ARG D 4 89  ? 123.305 102.877 174.740 1.00 41.18  ? 67  ARG N O   1 
ATOM   5571 C  CB  . ARG D 4 89  ? 124.512 100.556 173.537 1.00 34.89  ? 67  ARG N CB  1 
ATOM   5572 C  CG  . ARG D 4 89  ? 125.875 101.075 173.891 1.00 39.70  ? 67  ARG N CG  1 
ATOM   5573 C  CD  . ARG D 4 89  ? 126.700 99.989  174.548 1.00 40.90  ? 67  ARG N CD  1 
ATOM   5574 N  NE  . ARG D 4 89  ? 127.763 100.554 175.366 1.00 38.10  ? 67  ARG N NE  1 
ATOM   5575 C  CZ  . ARG D 4 89  ? 128.914 101.002 174.891 1.00 41.33  ? 67  ARG N CZ  1 
ATOM   5576 N  NH1 . ARG D 4 89  ? 129.199 100.938 173.602 1.00 41.51  ? 67  ARG N NH1 1 
ATOM   5577 N  NH2 . ARG D 4 89  ? 129.800 101.529 175.729 1.00 41.13  ? 67  ARG N NH2 1 
ATOM   5578 N  N   . PHE D 4 90  ? 123.793 104.010 172.864 1.00 34.41  ? 68  PHE N N   1 
ATOM   5579 C  CA  . PHE D 4 90  ? 123.487 105.327 173.408 1.00 30.41  ? 68  PHE N CA  1 
ATOM   5580 C  C   . PHE D 4 90  ? 122.431 105.981 172.531 1.00 36.79  ? 68  PHE N C   1 
ATOM   5581 O  O   . PHE D 4 90  ? 122.327 105.681 171.340 1.00 36.01  ? 68  PHE N O   1 
ATOM   5582 C  CB  . PHE D 4 90  ? 124.711 106.245 173.466 1.00 24.78  ? 68  PHE N CB  1 
ATOM   5583 C  CG  . PHE D 4 90  ? 125.649 105.959 174.600 1.00 29.55  ? 68  PHE N CG  1 
ATOM   5584 C  CD1 . PHE D 4 90  ? 125.553 104.797 175.331 1.00 36.05  ? 68  PHE N CD1 1 
ATOM   5585 C  CD2 . PHE D 4 90  ? 126.651 106.855 174.920 1.00 33.43  ? 68  PHE N CD2 1 
ATOM   5586 C  CE1 . PHE D 4 90  ? 126.431 104.538 176.359 1.00 34.75  ? 68  PHE N CE1 1 
ATOM   5587 C  CE2 . PHE D 4 90  ? 127.527 106.597 175.948 1.00 34.49  ? 68  PHE N CE2 1 
ATOM   5588 C  CZ  . PHE D 4 90  ? 127.418 105.435 176.663 1.00 31.07  ? 68  PHE N CZ  1 
ATOM   5589 N  N   . THR D 4 91  ? 121.641 106.874 173.121 1.00 39.80  ? 69  THR N N   1 
ATOM   5590 C  CA  . THR D 4 91  ? 120.601 107.582 172.377 1.00 34.88  ? 69  THR N CA  1 
ATOM   5591 C  C   . THR D 4 91  ? 120.532 109.029 172.842 1.00 34.96  ? 69  THR N C   1 
ATOM   5592 O  O   . THR D 4 91  ? 120.310 109.287 174.025 1.00 39.78  ? 69  THR N O   1 
ATOM   5593 C  CB  . THR D 4 91  ? 119.242 106.902 172.550 1.00 40.24  ? 69  THR N CB  1 
ATOM   5594 O  OG1 . THR D 4 91  ? 119.417 105.481 172.550 1.00 40.34  ? 69  THR N OG1 1 
ATOM   5595 C  CG2 . THR D 4 91  ? 118.307 107.283 171.424 1.00 36.03  ? 69  THR N CG2 1 
ATOM   5596 N  N   . ILE D 4 92  ? 120.700 109.967 171.918 1.00 25.40  ? 70  ILE N N   1 
ATOM   5597 C  CA  . ILE D 4 92  ? 120.629 111.388 172.229 1.00 21.86  ? 70  ILE N CA  1 
ATOM   5598 C  C   . ILE D 4 92  ? 119.290 111.926 171.757 1.00 26.27  ? 70  ILE N C   1 
ATOM   5599 O  O   . ILE D 4 92  ? 118.719 111.456 170.770 1.00 34.08  ? 70  ILE N O   1 
ATOM   5600 C  CB  . ILE D 4 92  ? 121.802 112.167 171.596 1.00 22.81  ? 70  ILE N CB  1 
ATOM   5601 C  CG1 . ILE D 4 92  ? 121.891 113.582 172.170 1.00 24.95  ? 70  ILE N CG1 1 
ATOM   5602 C  CG2 . ILE D 4 92  ? 121.668 112.214 170.101 1.00 12.02  ? 70  ILE N CG2 1 
ATOM   5603 C  CD1 . ILE D 4 92  ? 122.941 114.446 171.526 1.00 19.82  ? 70  ILE N CD1 1 
ATOM   5604 N  N   . SER D 4 93  ? 118.767 112.905 172.494 1.00 30.43  ? 71  SER N N   1 
ATOM   5605 C  CA  . SER D 4 93  ? 117.552 113.608 172.113 1.00 26.17  ? 71  SER N CA  1 
ATOM   5606 C  C   . SER D 4 93  ? 117.579 114.999 172.726 1.00 27.81  ? 71  SER N C   1 
ATOM   5607 O  O   . SER D 4 93  ? 118.335 115.271 173.658 1.00 32.72  ? 71  SER N O   1 
ATOM   5608 C  CB  . SER D 4 93  ? 116.294 112.851 172.550 1.00 26.14  ? 71  SER N CB  1 
ATOM   5609 O  OG  . SER D 4 93  ? 116.515 112.146 173.754 1.00 28.53  ? 71  SER N OG  1 
ATOM   5610 N  N   . ARG D 4 94  ? 116.759 115.888 172.181 1.00 30.29  ? 72  ARG N N   1 
ATOM   5611 C  CA  . ARG D 4 94  ? 116.646 117.241 172.699 1.00 24.43  ? 72  ARG N CA  1 
ATOM   5612 C  C   . ARG D 4 94  ? 115.182 117.634 172.795 1.00 29.71  ? 72  ARG N C   1 
ATOM   5613 O  O   . ARG D 4 94  ? 114.372 117.282 171.933 1.00 32.54  ? 72  ARG N O   1 
ATOM   5614 C  CB  . ARG D 4 94  ? 117.424 118.239 171.831 1.00 18.42  ? 72  ARG N CB  1 
ATOM   5615 C  CG  . ARG D 4 94  ? 116.676 118.828 170.662 1.00 18.89  ? 72  ARG N CG  1 
ATOM   5616 C  CD  . ARG D 4 94  ? 117.637 119.451 169.673 1.00 23.74  ? 72  ARG N CD  1 
ATOM   5617 N  NE  . ARG D 4 94  ? 117.859 120.869 169.926 1.00 25.39  ? 72  ARG N NE  1 
ATOM   5618 C  CZ  . ARG D 4 94  ? 118.904 121.553 169.482 1.00 21.45  ? 72  ARG N CZ  1 
ATOM   5619 N  NH1 . ARG D 4 94  ? 119.850 120.978 168.765 1.00 20.05  ? 72  ARG N NH1 1 
ATOM   5620 N  NH2 . ARG D 4 94  ? 119.003 122.844 169.768 1.00 26.77  ? 72  ARG N NH2 1 
ATOM   5621 N  N   . ASP D 4 95  ? 114.844 118.334 173.870 1.00 33.47  ? 73  ASP N N   1 
ATOM   5622 C  CA  . ASP D 4 95  ? 113.524 118.916 174.067 1.00 33.77  ? 73  ASP N CA  1 
ATOM   5623 C  C   . ASP D 4 95  ? 113.683 120.427 173.966 1.00 35.22  ? 73  ASP N C   1 
ATOM   5624 O  O   . ASP D 4 95  ? 114.245 121.062 174.867 1.00 39.84  ? 73  ASP N O   1 
ATOM   5625 C  CB  . ASP D 4 95  ? 112.934 118.502 175.411 1.00 36.70  ? 73  ASP N CB  1 
ATOM   5626 C  CG  . ASP D 4 95  ? 111.430 118.623 175.447 1.00 39.49  ? 73  ASP N CG  1 
ATOM   5627 O  OD1 . ASP D 4 95  ? 110.839 119.000 174.415 1.00 37.06  ? 73  ASP N OD1 1 
ATOM   5628 O  OD2 . ASP D 4 95  ? 110.836 118.344 176.507 1.00 41.15  ? 73  ASP N OD2 1 
ATOM   5629 N  N   . ASN D 4 96  ? 113.212 120.992 172.855 1.00 27.62  ? 74  ASN N N   1 
ATOM   5630 C  CA  . ASN D 4 96  ? 113.400 122.411 172.597 1.00 29.77  ? 74  ASN N CA  1 
ATOM   5631 C  C   . ASN D 4 96  ? 112.436 123.274 173.396 1.00 38.38  ? 74  ASN N C   1 
ATOM   5632 O  O   . ASN D 4 96  ? 112.769 124.413 173.733 1.00 39.44  ? 74  ASN N O   1 
ATOM   5633 C  CB  . ASN D 4 96  ? 113.251 122.688 171.105 1.00 31.98  ? 74  ASN N CB  1 
ATOM   5634 C  CG  . ASN D 4 96  ? 114.447 122.226 170.311 1.00 30.97  ? 74  ASN N CG  1 
ATOM   5635 O  OD1 . ASN D 4 96  ? 115.547 122.117 170.841 1.00 29.37  ? 74  ASN N OD1 1 
ATOM   5636 N  ND2 . ASN D 4 96  ? 114.240 121.945 169.034 1.00 30.81  ? 74  ASN N ND2 1 
ATOM   5637 N  N   . ALA D 4 97  ? 111.237 122.767 173.686 1.00 44.17  ? 75  ALA N N   1 
ATOM   5638 C  CA  . ALA D 4 97  ? 110.289 123.531 174.489 1.00 40.91  ? 75  ALA N CA  1 
ATOM   5639 C  C   . ALA D 4 97  ? 110.783 123.692 175.918 1.00 41.09  ? 75  ALA N C   1 
ATOM   5640 O  O   . ALA D 4 97  ? 110.617 124.758 176.520 1.00 43.50  ? 75  ALA N O   1 
ATOM   5641 C  CB  . ALA D 4 97  ? 108.917 122.859 174.464 1.00 40.16  ? 75  ALA N CB  1 
ATOM   5642 N  N   . LYS D 4 98  ? 111.387 122.650 176.479 1.00 37.99  ? 76  LYS N N   1 
ATOM   5643 C  CA  . LYS D 4 98  ? 111.922 122.694 177.832 1.00 33.27  ? 76  LYS N CA  1 
ATOM   5644 C  C   . LYS D 4 98  ? 113.401 123.045 177.876 1.00 38.72  ? 76  LYS N C   1 
ATOM   5645 O  O   . LYS D 4 98  ? 113.956 123.161 178.973 1.00 44.62  ? 76  LYS N O   1 
ATOM   5646 C  CB  . LYS D 4 98  ? 111.695 121.355 178.534 1.00 34.54  ? 76  LYS N CB  1 
ATOM   5647 C  CG  . LYS D 4 98  ? 110.311 121.203 179.137 1.00 41.99  ? 76  LYS N CG  1 
ATOM   5648 C  CD  . LYS D 4 98  ? 110.153 119.857 179.824 1.00 40.52  ? 76  LYS N CD  1 
ATOM   5649 C  CE  . LYS D 4 98  ? 111.250 119.633 180.850 1.00 42.18  ? 76  LYS N CE  1 
ATOM   5650 N  NZ  . LYS D 4 98  ? 111.266 120.700 181.887 1.00 39.70  ? 76  LYS N NZ  1 
ATOM   5651 N  N   . ASN D 4 99  ? 114.048 123.208 176.721 1.00 34.21  ? 77  ASN N N   1 
ATOM   5652 C  CA  . ASN D 4 99  ? 115.445 123.633 176.631 1.00 32.55  ? 77  ASN N CA  1 
ATOM   5653 C  C   . ASN D 4 99  ? 116.372 122.660 177.360 1.00 37.81  ? 77  ASN N C   1 
ATOM   5654 O  O   . ASN D 4 99  ? 117.097 123.029 178.283 1.00 36.28  ? 77  ASN N O   1 
ATOM   5655 C  CB  . ASN D 4 99  ? 115.621 125.056 177.176 1.00 34.07  ? 77  ASN N CB  1 
ATOM   5656 C  CG  . ASN D 4 99  ? 115.000 126.108 176.288 1.00 35.47  ? 77  ASN N CG  1 
ATOM   5657 O  OD1 . ASN D 4 99  ? 114.713 125.863 175.122 1.00 38.28  ? 77  ASN N OD1 1 
ATOM   5658 N  ND2 . ASN D 4 99  ? 114.801 127.295 176.837 1.00 39.88  ? 77  ASN N ND2 1 
ATOM   5659 N  N   . THR D 4 100 ? 116.348 121.402 176.925 1.00 36.01  ? 78  THR N N   1 
ATOM   5660 C  CA  . THR D 4 100 ? 117.153 120.395 177.603 1.00 30.19  ? 78  THR N CA  1 
ATOM   5661 C  C   . THR D 4 100 ? 117.646 119.360 176.603 1.00 31.73  ? 78  THR N C   1 
ATOM   5662 O  O   . THR D 4 100 ? 117.037 119.151 175.553 1.00 31.09  ? 78  THR N O   1 
ATOM   5663 C  CB  . THR D 4 100 ? 116.364 119.727 178.736 1.00 28.50  ? 78  THR N CB  1 
ATOM   5664 O  OG1 . THR D 4 100 ? 117.222 118.851 179.473 1.00 31.06  ? 78  THR N OG1 1 
ATOM   5665 C  CG2 . THR D 4 100 ? 115.198 118.943 178.187 1.00 29.28  ? 78  THR N CG2 1 
ATOM   5666 N  N   . LEU D 4 101 ? 118.769 118.725 176.938 1.00 31.16  ? 79  LEU N N   1 
ATOM   5667 C  CA  . LEU D 4 101 ? 119.406 117.718 176.101 1.00 20.35  ? 79  LEU N CA  1 
ATOM   5668 C  C   . LEU D 4 101 ? 119.626 116.462 176.926 1.00 27.06  ? 79  LEU N C   1 
ATOM   5669 O  O   . LEU D 4 101 ? 119.850 116.537 178.134 1.00 33.10  ? 79  LEU N O   1 
ATOM   5670 C  CB  . LEU D 4 101 ? 120.738 118.222 175.552 1.00 20.69  ? 79  LEU N CB  1 
ATOM   5671 C  CG  . LEU D 4 101 ? 121.441 117.418 174.468 1.00 24.28  ? 79  LEU N CG  1 
ATOM   5672 C  CD1 . LEU D 4 101 ? 120.929 117.831 173.118 1.00 28.17  ? 79  LEU N CD1 1 
ATOM   5673 C  CD2 . LEU D 4 101 ? 122.930 117.628 174.551 1.00 21.58  ? 79  LEU N CD2 1 
ATOM   5674 N  N   . TYR D 4 102 ? 119.569 115.300 176.275 1.00 33.82  ? 80  TYR N N   1 
ATOM   5675 C  CA  . TYR D 4 102 ? 119.625 114.030 176.984 1.00 32.29  ? 80  TYR N CA  1 
ATOM   5676 C  C   . TYR D 4 102 ? 120.680 113.105 176.397 1.00 29.16  ? 80  TYR N C   1 
ATOM   5677 O  O   . TYR D 4 102 ? 121.150 113.279 175.272 1.00 18.85  ? 80  TYR N O   1 
ATOM   5678 C  CB  . TYR D 4 102 ? 118.283 113.302 176.955 1.00 30.17  ? 80  TYR N CB  1 
ATOM   5679 C  CG  . TYR D 4 102 ? 117.140 114.062 177.566 1.00 31.76  ? 80  TYR N CG  1 
ATOM   5680 C  CD1 . TYR D 4 102 ? 116.945 114.072 178.934 1.00 31.51  ? 80  TYR N CD1 1 
ATOM   5681 C  CD2 . TYR D 4 102 ? 116.237 114.741 176.771 1.00 29.35  ? 80  TYR N CD2 1 
ATOM   5682 C  CE1 . TYR D 4 102 ? 115.894 114.753 179.492 1.00 31.41  ? 80  TYR N CE1 1 
ATOM   5683 C  CE2 . TYR D 4 102 ? 115.185 115.420 177.318 1.00 33.19  ? 80  TYR N CE2 1 
ATOM   5684 C  CZ  . TYR D 4 102 ? 115.016 115.425 178.679 1.00 37.21  ? 80  TYR N CZ  1 
ATOM   5685 O  OH  . TYR D 4 102 ? 113.959 116.109 179.227 1.00 42.88  ? 80  TYR N OH  1 
ATOM   5686 N  N   . LEU D 4 103 ? 121.044 112.112 177.200 1.00 32.86  ? 81  LEU N N   1 
ATOM   5687 C  CA  . LEU D 4 103 ? 121.814 110.965 176.729 1.00 32.38  ? 81  LEU N CA  1 
ATOM   5688 C  C   . LEU D 4 103 ? 121.329 109.754 177.509 1.00 34.24  ? 81  LEU N C   1 
ATOM   5689 O  O   . LEU D 4 103 ? 121.550 109.669 178.720 1.00 36.15  ? 81  LEU N O   1 
ATOM   5690 C  CB  . LEU D 4 103 ? 123.311 111.177 176.917 1.00 32.82  ? 81  LEU N CB  1 
ATOM   5691 C  CG  . LEU D 4 103 ? 124.259 110.163 176.286 1.00 28.20  ? 81  LEU N CG  1 
ATOM   5692 C  CD1 . LEU D 4 103 ? 124.271 110.314 174.783 1.00 30.46  ? 81  LEU N CD1 1 
ATOM   5693 C  CD2 . LEU D 4 103 ? 125.650 110.334 176.841 1.00 25.06  ? 81  LEU N CD2 1 
ATOM   5694 N  N   . GLN D 4 104 ? 120.647 108.843 176.826 1.00 37.49  ? 82  GLN N N   1 
ATOM   5695 C  CA  . GLN D 4 104 ? 120.234 107.576 177.406 1.00 41.47  ? 82  GLN N CA  1 
ATOM   5696 C  C   . GLN D 4 104 ? 121.332 106.554 177.154 1.00 43.55  ? 82  GLN N C   1 
ATOM   5697 O  O   . GLN D 4 104 ? 121.640 106.246 175.998 1.00 46.44  ? 82  GLN N O   1 
ATOM   5698 C  CB  . GLN D 4 104 ? 118.915 107.109 176.800 1.00 37.79  ? 82  GLN N CB  1 
ATOM   5699 C  CG  . GLN D 4 104 ? 118.515 105.719 177.217 1.00 40.80  ? 82  GLN N CG  1 
ATOM   5700 C  CD  . GLN D 4 104 ? 117.965 105.678 178.619 1.00 41.34  ? 82  GLN N CD  1 
ATOM   5701 O  OE1 . GLN D 4 104 ? 116.814 106.030 178.853 1.00 41.76  ? 82  GLN N OE1 1 
ATOM   5702 N  NE2 . GLN D 4 104 ? 118.786 105.250 179.564 1.00 39.42  ? 82  GLN N NE2 1 
ATOM   5703 N  N   . MET D 4 105 ? 121.930 106.048 178.230 1.00 42.57  ? 83  MET N N   1 
ATOM   5704 C  CA  . MET D 4 105 ? 123.075 105.152 178.170 1.00 40.55  ? 83  MET N CA  1 
ATOM   5705 C  C   . MET D 4 105 ? 122.656 103.820 178.769 1.00 46.41  ? 83  MET N C   1 
ATOM   5706 O  O   . MET D 4 105 ? 122.529 103.705 179.990 1.00 51.24  ? 83  MET N O   1 
ATOM   5707 C  CB  . MET D 4 105 ? 124.248 105.733 178.955 1.00 47.35  ? 83  MET N CB  1 
ATOM   5708 C  CG  . MET D 4 105 ? 124.228 107.239 179.104 1.00 40.66  ? 83  MET N CG  1 
ATOM   5709 S  SD  . MET D 4 105 ? 125.483 107.835 180.250 1.00 47.46  ? 83  MET N SD  1 
ATOM   5710 C  CE  . MET D 4 105 ? 126.968 107.104 179.593 1.00 40.32  ? 83  MET N CE  1 
ATOM   5711 N  N   . ASN D 4 106 ? 122.452 102.810 177.933 1.00 50.17  ? 84  ASN N N   1 
ATOM   5712 C  CA  . ASN D 4 106 ? 122.147 101.481 178.437 1.00 53.79  ? 84  ASN N CA  1 
ATOM   5713 C  C   . ASN D 4 106 ? 123.179 100.484 177.927 1.00 51.29  ? 84  ASN N C   1 
ATOM   5714 O  O   . ASN D 4 106 ? 123.874 100.729 176.939 1.00 50.11  ? 84  ASN N O   1 
ATOM   5715 C  CB  . ASN D 4 106 ? 120.716 101.045 178.074 1.00 50.21  ? 84  ASN N CB  1 
ATOM   5716 C  CG  . ASN D 4 106 ? 120.341 101.376 176.653 1.00 48.65  ? 84  ASN N CG  1 
ATOM   5717 O  OD1 . ASN D 4 106 ? 121.198 101.604 175.809 1.00 53.13  ? 84  ASN N OD1 1 
ATOM   5718 N  ND2 . ASN D 4 106 ? 119.045 101.414 176.383 1.00 44.93  ? 84  ASN N ND2 1 
ATOM   5719 N  N   . SER D 4 107 ? 123.285 99.362  178.641 1.00 58.65  ? 85  SER N N   1 
ATOM   5720 C  CA  . SER D 4 107 ? 124.335 98.367  178.428 1.00 59.78  ? 85  SER N CA  1 
ATOM   5721 C  C   . SER D 4 107 ? 125.716 98.996  178.616 1.00 61.35  ? 85  SER N C   1 
ATOM   5722 O  O   . SER D 4 107 ? 126.525 99.078  177.693 1.00 61.30  ? 85  SER N O   1 
ATOM   5723 C  CB  . SER D 4 107 ? 124.208 97.710  177.050 1.00 59.63  ? 85  SER N CB  1 
ATOM   5724 O  OG  . SER D 4 107 ? 123.049 96.900  176.974 1.00 60.55  ? 85  SER N OG  1 
ATOM   5725 N  N   . LEU D 4 108 ? 125.967 99.450  179.840 1.00 62.52  ? 86  LEU N N   1 
ATOM   5726 C  CA  . LEU D 4 108 ? 127.203 100.152 180.150 1.00 62.10  ? 86  LEU N CA  1 
ATOM   5727 C  C   . LEU D 4 108 ? 128.344 99.172  180.389 1.00 63.59  ? 86  LEU N C   1 
ATOM   5728 O  O   . LEU D 4 108 ? 128.135 98.025  180.789 1.00 66.71  ? 86  LEU N O   1 
ATOM   5729 C  CB  . LEU D 4 108 ? 127.018 101.048 181.374 1.00 65.20  ? 86  LEU N CB  1 
ATOM   5730 C  CG  . LEU D 4 108 ? 126.390 102.426 181.144 1.00 61.56  ? 86  LEU N CG  1 
ATOM   5731 C  CD1 . LEU D 4 108 ? 126.564 103.296 182.367 1.00 63.00  ? 86  LEU N CD1 1 
ATOM   5732 C  CD2 . LEU D 4 108 ? 126.989 103.100 179.932 1.00 59.42  ? 86  LEU N CD2 1 
ATOM   5733 N  N   . LYS D 4 109 ? 129.558 99.641  180.143 1.00 63.78  ? 87  LYS N N   1 
ATOM   5734 C  CA  . LYS D 4 109 ? 130.779 98.860  180.255 1.00 62.99  ? 87  LYS N CA  1 
ATOM   5735 C  C   . LYS D 4 109 ? 131.741 99.567  181.194 1.00 64.13  ? 87  LYS N C   1 
ATOM   5736 O  O   . LYS D 4 109 ? 131.651 100.784 181.385 1.00 64.01  ? 87  LYS N O   1 
ATOM   5737 C  CB  . LYS D 4 109 ? 131.447 98.672  178.886 1.00 61.48  ? 87  LYS N CB  1 
ATOM   5738 C  CG  . LYS D 4 109 ? 130.526 98.166  177.802 1.00 60.96  ? 87  LYS N CG  1 
ATOM   5739 C  CD  . LYS D 4 109 ? 131.254 98.070  176.479 1.00 60.31  ? 87  LYS N CD  1 
ATOM   5740 C  CE  . LYS D 4 109 ? 130.403 97.370  175.440 1.00 62.39  ? 87  LYS N CE  1 
ATOM   5741 N  NZ  . LYS D 4 109 ? 131.214 96.900  174.288 1.00 64.88  ? 87  LYS N NZ  1 
ATOM   5742 N  N   . PRO D 4 110 ? 132.675 98.831  181.801 1.00 71.73  ? 88  PRO N N   1 
ATOM   5743 C  CA  . PRO D 4 110 ? 133.668 99.487  182.671 1.00 69.51  ? 88  PRO N CA  1 
ATOM   5744 C  C   . PRO D 4 110 ? 134.527 100.503 181.945 1.00 67.28  ? 88  PRO N C   1 
ATOM   5745 O  O   . PRO D 4 110 ? 135.150 101.344 182.600 1.00 66.74  ? 88  PRO N O   1 
ATOM   5746 C  CB  . PRO D 4 110 ? 134.518 98.325  183.204 1.00 67.27  ? 88  PRO N CB  1 
ATOM   5747 C  CG  . PRO D 4 110 ? 133.880 97.077  182.753 1.00 68.83  ? 88  PRO N CG  1 
ATOM   5748 C  CD  . PRO D 4 110 ? 132.696 97.364  181.903 1.00 70.97  ? 88  PRO N CD  1 
ATOM   5749 N  N   . GLU D 4 111 ? 134.600 100.437 180.616 1.00 64.51  ? 89  GLU N N   1 
ATOM   5750 C  CA  . GLU D 4 111 ? 135.328 101.431 179.838 1.00 63.63  ? 89  GLU N CA  1 
ATOM   5751 C  C   . GLU D 4 111 ? 134.636 102.790 179.860 1.00 66.96  ? 89  GLU N C   1 
ATOM   5752 O  O   . GLU D 4 111 ? 135.315 103.818 179.809 1.00 68.52  ? 89  GLU N O   1 
ATOM   5753 C  CB  . GLU D 4 111 ? 135.496 100.905 178.407 1.00 62.42  ? 89  GLU N CB  1 
ATOM   5754 C  CG  . GLU D 4 111 ? 136.475 101.631 177.482 1.00 64.20  ? 89  GLU N CG  1 
ATOM   5755 C  CD  . GLU D 4 111 ? 135.953 102.945 176.928 1.00 66.55  ? 89  GLU N CD  1 
ATOM   5756 O  OE1 . GLU D 4 111 ? 136.319 104.016 177.453 1.00 65.97  ? 89  GLU N OE1 1 
ATOM   5757 O  OE2 . GLU D 4 111 ? 135.174 102.904 175.953 1.00 66.24  ? 89  GLU N OE2 1 
ATOM   5758 N  N   . ASP D 4 112 ? 133.312 102.817 179.997 1.00 62.27  ? 90  ASP N N   1 
ATOM   5759 C  CA  . ASP D 4 112 ? 132.512 104.028 179.864 1.00 58.28  ? 90  ASP N CA  1 
ATOM   5760 C  C   . ASP D 4 112 ? 132.625 104.987 181.048 1.00 61.11  ? 90  ASP N C   1 
ATOM   5761 O  O   . ASP D 4 112 ? 131.859 105.952 181.098 1.00 60.11  ? 90  ASP N O   1 
ATOM   5762 C  CB  . ASP D 4 112 ? 131.042 103.658 179.665 1.00 56.52  ? 90  ASP N CB  1 
ATOM   5763 C  CG  . ASP D 4 112 ? 130.771 103.079 178.300 1.00 60.79  ? 90  ASP N CG  1 
ATOM   5764 O  OD1 . ASP D 4 112 ? 131.740 102.850 177.550 1.00 61.67  ? 90  ASP N OD1 1 
ATOM   5765 O  OD2 . ASP D 4 112 ? 129.589 102.850 177.973 1.00 63.66  ? 90  ASP N OD2 1 
ATOM   5766 N  N   . THR D 4 113 ? 133.534 104.763 181.996 1.00 62.07  ? 91  THR N N   1 
ATOM   5767 C  CA  . THR D 4 113 ? 133.648 105.653 183.145 1.00 59.62  ? 91  THR N CA  1 
ATOM   5768 C  C   . THR D 4 113 ? 134.459 106.887 182.773 1.00 59.23  ? 91  THR N C   1 
ATOM   5769 O  O   . THR D 4 113 ? 135.585 106.773 182.282 1.00 61.76  ? 91  THR N O   1 
ATOM   5770 C  CB  . THR D 4 113 ? 134.292 104.934 184.330 1.00 60.21  ? 91  THR N CB  1 
ATOM   5771 O  OG1 . THR D 4 113 ? 135.592 104.467 183.954 1.00 61.43  ? 91  THR N OG1 1 
ATOM   5772 C  CG2 . THR D 4 113 ? 133.456 103.751 184.765 1.00 57.01  ? 91  THR N CG2 1 
ATOM   5773 N  N   . ALA D 4 114 ? 133.891 108.064 183.019 1.00 51.82  ? 92  ALA N N   1 
ATOM   5774 C  CA  . ALA D 4 114 ? 134.498 109.318 182.584 1.00 47.62  ? 92  ALA N CA  1 
ATOM   5775 C  C   . ALA D 4 114 ? 133.674 110.471 183.135 1.00 49.84  ? 92  ALA N C   1 
ATOM   5776 O  O   . ALA D 4 114 ? 132.629 110.271 183.758 1.00 55.01  ? 92  ALA N O   1 
ATOM   5777 C  CB  . ALA D 4 114 ? 134.582 109.396 181.060 1.00 46.78  ? 92  ALA N CB  1 
ATOM   5778 N  N   . VAL D 4 115 ? 134.142 111.687 182.882 1.00 45.51  ? 93  VAL N N   1 
ATOM   5779 C  CA  . VAL D 4 115 ? 133.352 112.888 183.121 1.00 44.39  ? 93  VAL N CA  1 
ATOM   5780 C  C   . VAL D 4 115 ? 132.656 113.254 181.818 1.00 45.14  ? 93  VAL N C   1 
ATOM   5781 O  O   . VAL D 4 115 ? 133.278 113.240 180.752 1.00 44.50  ? 93  VAL N O   1 
ATOM   5782 C  CB  . VAL D 4 115 ? 134.236 114.039 183.622 1.00 44.67  ? 93  VAL N CB  1 
ATOM   5783 C  CG1 . VAL D 4 115 ? 133.396 115.257 183.931 1.00 42.45  ? 93  VAL N CG1 1 
ATOM   5784 C  CG2 . VAL D 4 115 ? 135.013 113.605 184.842 1.00 45.72  ? 93  VAL N CG2 1 
ATOM   5785 N  N   . TYR D 4 116 ? 131.363 113.553 181.890 1.00 37.15  ? 94  TYR N N   1 
ATOM   5786 C  CA  . TYR D 4 116 ? 130.558 113.819 180.708 1.00 34.57  ? 94  TYR N CA  1 
ATOM   5787 C  C   . TYR D 4 116 ? 130.109 115.272 180.700 1.00 39.69  ? 94  TYR N C   1 
ATOM   5788 O  O   . TYR D 4 116 ? 129.519 115.747 181.675 1.00 45.92  ? 94  TYR N O   1 
ATOM   5789 C  CB  . TYR D 4 116 ? 129.354 112.880 180.656 1.00 39.38  ? 94  TYR N CB  1 
ATOM   5790 C  CG  . TYR D 4 116 ? 129.720 111.492 180.188 1.00 43.59  ? 94  TYR N CG  1 
ATOM   5791 C  CD1 . TYR D 4 116 ? 130.217 110.552 181.074 1.00 43.95  ? 94  TYR N CD1 1 
ATOM   5792 C  CD2 . TYR D 4 116 ? 129.590 111.130 178.857 1.00 34.91  ? 94  TYR N CD2 1 
ATOM   5793 C  CE1 . TYR D 4 116 ? 130.567 109.292 180.653 1.00 41.39  ? 94  TYR N CE1 1 
ATOM   5794 C  CE2 . TYR D 4 116 ? 129.939 109.871 178.430 1.00 37.36  ? 94  TYR N CE2 1 
ATOM   5795 C  CZ  . TYR D 4 116 ? 130.425 108.957 179.333 1.00 40.50  ? 94  TYR N CZ  1 
ATOM   5796 O  OH  . TYR D 4 116 ? 130.774 107.697 178.913 1.00 39.82  ? 94  TYR N OH  1 
ATOM   5797 N  N   . TYR D 4 117 ? 130.403 115.972 179.604 1.00 35.11  ? 95  TYR N N   1 
ATOM   5798 C  CA  . TYR D 4 117 ? 130.041 117.366 179.416 1.00 32.40  ? 95  TYR N CA  1 
ATOM   5799 C  C   . TYR D 4 117 ? 129.082 117.515 178.243 1.00 36.02  ? 95  TYR N C   1 
ATOM   5800 O  O   . TYR D 4 117 ? 129.107 116.739 177.284 1.00 35.09  ? 95  TYR N O   1 
ATOM   5801 C  CB  . TYR D 4 117 ? 131.257 118.251 179.152 1.00 32.06  ? 95  TYR N CB  1 
ATOM   5802 C  CG  . TYR D 4 117 ? 132.460 117.984 180.016 1.00 35.35  ? 95  TYR N CG  1 
ATOM   5803 C  CD1 . TYR D 4 117 ? 133.431 117.082 179.624 1.00 32.06  ? 95  TYR N CD1 1 
ATOM   5804 C  CD2 . TYR D 4 117 ? 132.643 118.663 181.204 1.00 39.28  ? 95  TYR N CD2 1 
ATOM   5805 C  CE1 . TYR D 4 117 ? 134.532 116.850 180.402 1.00 32.21  ? 95  TYR N CE1 1 
ATOM   5806 C  CE2 . TYR D 4 117 ? 133.742 118.433 181.989 1.00 36.21  ? 95  TYR N CE2 1 
ATOM   5807 C  CZ  . TYR D 4 117 ? 134.681 117.527 181.584 1.00 34.39  ? 95  TYR N CZ  1 
ATOM   5808 O  OH  . TYR D 4 117 ? 135.782 117.299 182.369 1.00 39.85  ? 95  TYR N OH  1 
ATOM   5809 N  N   . CYS D 4 118 ? 128.251 118.540 178.335 1.00 31.97  ? 96  CYS N N   1 
ATOM   5810 C  CA  . CYS D 4 118 ? 127.257 118.894 177.331 1.00 21.15  ? 96  CYS N CA  1 
ATOM   5811 C  C   . CYS D 4 118 ? 127.743 120.170 176.658 1.00 25.55  ? 96  CYS N C   1 
ATOM   5812 O  O   . CYS D 4 118 ? 127.857 121.211 177.309 1.00 33.51  ? 96  CYS N O   1 
ATOM   5813 C  CB  . CYS D 4 118 ? 125.899 119.066 178.008 1.00 24.82  ? 96  CYS N CB  1 
ATOM   5814 S  SG  . CYS D 4 118 ? 124.607 119.945 177.151 1.00 43.32  ? 96  CYS N SG  1 
ATOM   5815 N  N   . ALA D 4 119 ? 128.056 120.088 175.368 1.00 19.08  ? 97  ALA N N   1 
ATOM   5816 C  CA  . ALA D 4 119 ? 128.723 121.168 174.659 1.00 9.44   ? 97  ALA N CA  1 
ATOM   5817 C  C   . ALA D 4 119 ? 127.821 121.766 173.587 1.00 15.51  ? 97  ALA N C   1 
ATOM   5818 O  O   . ALA D 4 119 ? 126.890 121.126 173.096 1.00 31.94  ? 97  ALA N O   1 
ATOM   5819 C  CB  . ALA D 4 119 ? 130.026 120.679 174.034 1.00 3.32   ? 97  ALA N CB  1 
ATOM   5820 N  N   . ARG D 4 120 ? 128.120 123.011 173.222 1.00 14.26  ? 98  ARG N N   1 
ATOM   5821 C  CA  . ARG D 4 120 ? 127.289 123.803 172.329 1.00 13.83  ? 98  ARG N CA  1 
ATOM   5822 C  C   . ARG D 4 120 ? 128.127 124.352 171.183 1.00 23.95  ? 98  ARG N C   1 
ATOM   5823 O  O   . ARG D 4 120 ? 129.296 124.696 171.362 1.00 27.19  ? 98  ARG N O   1 
ATOM   5824 C  CB  . ARG D 4 120 ? 126.622 124.953 173.093 1.00 19.65  ? 98  ARG N CB  1 
ATOM   5825 C  CG  . ARG D 4 120 ? 125.521 125.681 172.342 1.00 13.28  ? 98  ARG N CG  1 
ATOM   5826 C  CD  . ARG D 4 120 ? 125.428 127.131 172.778 1.00 17.15  ? 98  ARG N CD  1 
ATOM   5827 N  NE  . ARG D 4 120 ? 126.289 127.990 171.978 1.00 22.85  ? 98  ARG N NE  1 
ATOM   5828 C  CZ  . ARG D 4 120 ? 126.444 129.290 172.166 1.00 12.94  ? 98  ARG N CZ  1 
ATOM   5829 N  NH1 . ARG D 4 120 ? 125.800 129.930 173.121 1.00 10.16  ? 98  ARG N NH1 1 
ATOM   5830 N  NH2 . ARG D 4 120 ? 127.266 129.963 171.375 1.00 10.66  ? 98  ARG N NH2 1 
ATOM   5831 N  N   . CYS D 4 121 ? 127.514 124.440 170.004 1.00 22.93  ? 99  CYS N N   1 
ATOM   5832 C  CA  . CYS D 4 121 ? 128.208 124.957 168.834 1.00 15.14  ? 99  CYS N CA  1 
ATOM   5833 C  C   . CYS D 4 121 ? 128.572 126.427 169.037 1.00 23.34  ? 99  CYS N C   1 
ATOM   5834 O  O   . CYS D 4 121 ? 127.883 127.150 169.758 1.00 27.77  ? 99  CYS N O   1 
ATOM   5835 C  CB  . CYS D 4 121 ? 127.343 124.815 167.586 1.00 18.90  ? 99  CYS N CB  1 
ATOM   5836 S  SG  . CYS D 4 121 ? 127.685 123.413 166.485 1.00 49.56  ? 99  CYS N SG  1 
ATOM   5837 N  N   . PRO D 4 122 ? 129.663 126.893 168.424 1.00 27.61  ? 100 PRO N N   1 
ATOM   5838 C  CA  . PRO D 4 122 ? 130.065 128.292 168.634 1.00 16.46  ? 100 PRO N CA  1 
ATOM   5839 C  C   . PRO D 4 122 ? 129.063 129.314 168.126 1.00 24.07  ? 100 PRO N C   1 
ATOM   5840 O  O   . PRO D 4 122 ? 128.907 130.367 168.751 1.00 31.20  ? 100 PRO N O   1 
ATOM   5841 C  CB  . PRO D 4 122 ? 131.400 128.378 167.882 1.00 17.82  ? 100 PRO N CB  1 
ATOM   5842 C  CG  . PRO D 4 122 ? 131.867 126.991 167.761 1.00 8.88   ? 100 PRO N CG  1 
ATOM   5843 C  CD  . PRO D 4 122 ? 130.648 126.164 167.610 1.00 16.95  ? 100 PRO N CD  1 
ATOM   5844 N  N   . ALA D 4 123 ? 128.377 129.042 167.019 1.00 21.34  ? 101 ALA N N   1 
ATOM   5845 C  CA  . ALA D 4 123 ? 127.547 130.021 166.335 1.00 5.08   ? 101 ALA N CA  1 
ATOM   5846 C  C   . ALA D 4 123 ? 126.226 129.391 165.925 1.00 21.81  ? 101 ALA N C   1 
ATOM   5847 O  O   . ALA D 4 123 ? 126.150 128.170 165.750 1.00 32.42  ? 101 ALA N O   1 
ATOM   5848 C  CB  . ALA D 4 123 ? 128.256 130.575 165.092 1.00 9.80   ? 101 ALA N CB  1 
ATOM   5849 N  N   . PRO D 4 124 ? 125.173 130.189 165.766 1.00 27.29  ? 102 PRO N N   1 
ATOM   5850 C  CA  . PRO D 4 124 ? 123.879 129.637 165.362 1.00 17.45  ? 102 PRO N CA  1 
ATOM   5851 C  C   . PRO D 4 124 ? 123.777 129.441 163.859 1.00 21.36  ? 102 PRO N C   1 
ATOM   5852 O  O   . PRO D 4 124 ? 124.484 130.064 163.068 1.00 28.68  ? 102 PRO N O   1 
ATOM   5853 C  CB  . PRO D 4 124 ? 122.887 130.700 165.835 1.00 10.43  ? 102 PRO N CB  1 
ATOM   5854 C  CG  . PRO D 4 124 ? 123.639 131.944 165.752 1.00 15.70  ? 102 PRO N CG  1 
ATOM   5855 C  CD  . PRO D 4 124 ? 125.059 131.616 166.109 1.00 22.97  ? 102 PRO N CD  1 
ATOM   5856 N  N   . PHE D 4 125 ? 122.873 128.543 163.478 1.00 20.27  ? 103 PHE N N   1 
ATOM   5857 C  CA  . PHE D 4 125 ? 122.452 128.289 162.105 1.00 22.43  ? 103 PHE N CA  1 
ATOM   5858 C  C   . PHE D 4 125 ? 123.540 127.661 161.245 1.00 23.28  ? 103 PHE N C   1 
ATOM   5859 O  O   . PHE D 4 125 ? 123.269 127.323 160.091 1.00 27.70  ? 103 PHE N O   1 
ATOM   5860 C  CB  . PHE D 4 125 ? 121.953 129.561 161.403 1.00 22.57  ? 103 PHE N CB  1 
ATOM   5861 C  CG  . PHE D 4 125 ? 120.828 130.247 162.117 1.00 24.00  ? 103 PHE N CG  1 
ATOM   5862 C  CD1 . PHE D 4 125 ? 119.661 129.570 162.408 1.00 25.56  ? 103 PHE N CD1 1 
ATOM   5863 C  CD2 . PHE D 4 125 ? 120.935 131.571 162.490 1.00 18.49  ? 103 PHE N CD2 1 
ATOM   5864 C  CE1 . PHE D 4 125 ? 118.631 130.199 163.063 1.00 22.04  ? 103 PHE N CE1 1 
ATOM   5865 C  CE2 . PHE D 4 125 ? 119.912 132.198 163.146 1.00 23.86  ? 103 PHE N CE2 1 
ATOM   5866 C  CZ  . PHE D 4 125 ? 118.759 131.513 163.431 1.00 24.07  ? 103 PHE N CZ  1 
ATOM   5867 N  N   . THR D 4 126 ? 124.750 127.483 161.758 1.00 20.87  ? 104 THR N N   1 
ATOM   5868 C  CA  . THR D 4 126 ? 125.846 126.957 160.962 1.00 21.75  ? 104 THR N CA  1 
ATOM   5869 C  C   . THR D 4 126 ? 125.813 125.436 160.939 1.00 26.27  ? 104 THR N C   1 
ATOM   5870 O  O   . THR D 4 126 ? 125.178 124.788 161.773 1.00 29.67  ? 104 THR N O   1 
ATOM   5871 C  CB  . THR D 4 126 ? 127.193 127.436 161.500 1.00 21.50  ? 104 THR N CB  1 
ATOM   5872 O  OG1 . THR D 4 126 ? 127.406 126.897 162.808 1.00 22.02  ? 104 THR N OG1 1 
ATOM   5873 C  CG2 . THR D 4 126 ? 127.233 128.949 161.569 1.00 20.60  ? 104 THR N CG2 1 
ATOM   5874 N  N   . ARG D 4 127 ? 126.515 124.868 159.961 1.00 24.82  ? 105 ARG N N   1 
ATOM   5875 C  CA  . ARG D 4 127 ? 126.576 123.422 159.812 1.00 26.34  ? 105 ARG N CA  1 
ATOM   5876 C  C   . ARG D 4 127 ? 127.784 122.808 160.506 1.00 28.78  ? 105 ARG N C   1 
ATOM   5877 O  O   . ARG D 4 127 ? 127.735 121.637 160.895 1.00 31.42  ? 105 ARG N O   1 
ATOM   5878 C  CB  . ARG D 4 127 ? 126.586 123.051 158.326 1.00 24.83  ? 105 ARG N CB  1 
ATOM   5879 C  CG  . ARG D 4 127 ? 126.544 121.556 158.063 1.00 28.92  ? 105 ARG N CG  1 
ATOM   5880 C  CD  . ARG D 4 127 ? 125.581 121.193 156.950 1.00 28.92  ? 105 ARG N CD  1 
ATOM   5881 N  NE  . ARG D 4 127 ? 125.747 119.805 156.537 1.00 31.24  ? 105 ARG N NE  1 
ATOM   5882 C  CZ  . ARG D 4 127 ? 125.430 119.337 155.339 1.00 33.41  ? 105 ARG N CZ  1 
ATOM   5883 N  NH1 . ARG D 4 127 ? 124.920 120.121 154.404 1.00 29.86  ? 105 ARG N NH1 1 
ATOM   5884 N  NH2 . ARG D 4 127 ? 125.631 118.050 155.071 1.00 29.67  ? 105 ARG N NH2 1 
ATOM   5885 N  N   . ASP D 4 128 ? 128.855 123.570 160.687 1.00 22.92  ? 106 ASP N N   1 
ATOM   5886 C  CA  . ASP D 4 128 ? 130.072 123.067 161.303 1.00 17.05  ? 106 ASP N CA  1 
ATOM   5887 C  C   . ASP D 4 128 ? 130.125 123.419 162.785 1.00 24.15  ? 106 ASP N C   1 
ATOM   5888 O  O   . ASP D 4 128 ? 129.725 124.508 163.200 1.00 34.32  ? 106 ASP N O   1 
ATOM   5889 C  CB  . ASP D 4 128 ? 131.296 123.642 160.596 1.00 18.93  ? 106 ASP N CB  1 
ATOM   5890 C  CG  . ASP D 4 128 ? 131.240 125.145 160.477 1.00 28.64  ? 106 ASP N CG  1 
ATOM   5891 O  OD1 . ASP D 4 128 ? 130.157 125.680 160.179 1.00 27.22  ? 106 ASP N OD1 1 
ATOM   5892 O  OD2 . ASP D 4 128 ? 132.281 125.798 160.680 1.00 32.69  ? 106 ASP N OD2 1 
ATOM   5893 N  N   . CYS D 4 129 ? 130.633 122.485 163.584 1.00 23.31  ? 107 CYS N N   1 
ATOM   5894 C  CA  . CYS D 4 129 ? 130.844 122.694 165.014 1.00 23.65  ? 107 CYS N CA  1 
ATOM   5895 C  C   . CYS D 4 129 ? 132.346 122.639 165.265 1.00 23.81  ? 107 CYS N C   1 
ATOM   5896 O  O   . CYS D 4 129 ? 132.916 121.565 165.460 1.00 29.75  ? 107 CYS N O   1 
ATOM   5897 C  CB  . CYS D 4 129 ? 130.089 121.665 165.860 1.00 17.26  ? 107 CYS N CB  1 
ATOM   5898 S  SG  . CYS D 4 129 ? 128.282 121.779 165.730 1.00 43.26  ? 107 CYS N SG  1 
ATOM   5899 N  N   . PHE D 4 130 ? 132.981 123.806 165.254 1.00 21.04  ? 108 PHE N N   1 
ATOM   5900 C  CA  . PHE D 4 130 ? 134.399 123.929 165.548 1.00 15.87  ? 108 PHE N CA  1 
ATOM   5901 C  C   . PHE D 4 130 ? 134.637 123.985 167.054 1.00 18.23  ? 108 PHE N C   1 
ATOM   5902 O  O   . PHE D 4 130 ? 133.804 124.472 167.817 1.00 28.29  ? 108 PHE N O   1 
ATOM   5903 C  CB  . PHE D 4 130 ? 134.964 125.199 164.908 1.00 17.01  ? 108 PHE N CB  1 
ATOM   5904 C  CG  . PHE D 4 130 ? 135.769 124.970 163.658 1.00 18.54  ? 108 PHE N CG  1 
ATOM   5905 C  CD1 . PHE D 4 130 ? 137.029 124.413 163.718 1.00 15.96  ? 108 PHE N CD1 1 
ATOM   5906 C  CD2 . PHE D 4 130 ? 135.280 125.360 162.429 1.00 13.53  ? 108 PHE N CD2 1 
ATOM   5907 C  CE1 . PHE D 4 130 ? 137.769 124.225 162.572 1.00 13.14  ? 108 PHE N CE1 1 
ATOM   5908 C  CE2 . PHE D 4 130 ? 136.017 125.172 161.288 1.00 7.09   ? 108 PHE N CE2 1 
ATOM   5909 C  CZ  . PHE D 4 130 ? 137.260 124.609 161.361 1.00 14.55  ? 108 PHE N CZ  1 
ATOM   5910 N  N   . ASP D 4 131 ? 135.788 123.466 167.475 1.00 21.24  ? 109 ASP N N   1 
ATOM   5911 C  CA  . ASP D 4 131 ? 136.425 123.750 168.761 1.00 21.76  ? 109 ASP N CA  1 
ATOM   5912 C  C   . ASP D 4 131 ? 135.719 123.153 169.968 1.00 17.63  ? 109 ASP N C   1 
ATOM   5913 O  O   . ASP D 4 131 ? 136.000 123.562 171.093 1.00 23.63  ? 109 ASP N O   1 
ATOM   5914 C  CB  . ASP D 4 131 ? 136.571 125.258 168.983 1.00 19.32  ? 109 ASP N CB  1 
ATOM   5915 C  CG  . ASP D 4 131 ? 137.655 125.863 168.135 1.00 21.90  ? 109 ASP N CG  1 
ATOM   5916 O  OD1 . ASP D 4 131 ? 138.359 125.111 167.438 1.00 28.73  ? 109 ASP N OD1 1 
ATOM   5917 O  OD2 . ASP D 4 131 ? 137.806 127.093 168.170 1.00 18.82  ? 109 ASP N OD2 1 
ATOM   5918 N  N   . VAL D 4 132 ? 134.832 122.179 169.777 1.00 17.18  ? 110 VAL N N   1 
ATOM   5919 C  CA  . VAL D 4 132 ? 133.986 121.731 170.877 1.00 17.19  ? 110 VAL N CA  1 
ATOM   5920 C  C   . VAL D 4 132 ? 134.760 120.904 171.905 1.00 13.68  ? 110 VAL N C   1 
ATOM   5921 O  O   . VAL D 4 132 ? 134.462 120.963 173.103 1.00 18.84  ? 110 VAL N O   1 
ATOM   5922 C  CB  . VAL D 4 132 ? 132.774 120.983 170.305 1.00 7.65   ? 110 VAL N CB  1 
ATOM   5923 C  CG1 . VAL D 4 132 ? 132.185 120.083 171.326 1.00 17.60  ? 110 VAL N CG1 1 
ATOM   5924 C  CG2 . VAL D 4 132 ? 131.750 121.978 169.848 1.00 9.03   ? 110 VAL N CG2 1 
ATOM   5925 N  N   . THR D 4 133 ? 135.761 120.137 171.480 1.00 17.98  ? 111 THR N N   1 
ATOM   5926 C  CA  . THR D 4 133 ? 136.528 119.294 172.397 1.00 22.79  ? 111 THR N CA  1 
ATOM   5927 C  C   . THR D 4 133 ? 137.886 119.890 172.719 1.00 23.98  ? 111 THR N C   1 
ATOM   5928 O  O   . THR D 4 133 ? 138.869 119.162 172.861 1.00 28.26  ? 111 THR N O   1 
ATOM   5929 C  CB  . THR D 4 133 ? 136.696 117.887 171.834 1.00 24.53  ? 111 THR N CB  1 
ATOM   5930 O  OG1 . THR D 4 133 ? 137.574 117.926 170.706 1.00 29.00  ? 111 THR N OG1 1 
ATOM   5931 C  CG2 . THR D 4 133 ? 135.361 117.310 171.412 1.00 24.43  ? 111 THR N CG2 1 
ATOM   5932 N  N   . SER D 4 134 ? 137.972 121.210 172.842 1.00 25.67  ? 112 SER N N   1 
ATOM   5933 C  CA  . SER D 4 134 ? 139.225 121.861 173.178 1.00 15.07  ? 112 SER N CA  1 
ATOM   5934 C  C   . SER D 4 134 ? 139.462 121.821 174.682 1.00 19.92  ? 112 SER N C   1 
ATOM   5935 O  O   . SER D 4 134 ? 138.558 121.553 175.474 1.00 22.26  ? 112 SER N O   1 
ATOM   5936 C  CB  . SER D 4 134 ? 139.230 123.304 172.687 1.00 16.63  ? 112 SER N CB  1 
ATOM   5937 O  OG  . SER D 4 134 ? 139.400 123.354 171.287 1.00 23.20  ? 112 SER N OG  1 
ATOM   5938 N  N   . THR D 4 135 ? 140.709 122.091 175.068 1.00 20.79  ? 113 THR N N   1 
ATOM   5939 C  CA  . THR D 4 135 ? 141.069 122.078 176.481 1.00 20.73  ? 113 THR N CA  1 
ATOM   5940 C  C   . THR D 4 135 ? 140.304 123.140 177.254 1.00 23.30  ? 113 THR N C   1 
ATOM   5941 O  O   . THR D 4 135 ? 139.812 122.882 178.358 1.00 25.19  ? 113 THR N O   1 
ATOM   5942 C  CB  . THR D 4 135 ? 142.572 122.289 176.641 1.00 25.20  ? 113 THR N CB  1 
ATOM   5943 O  OG1 . THR D 4 135 ? 143.270 121.562 175.623 1.00 29.18  ? 113 THR N OG1 1 
ATOM   5944 C  CG2 . THR D 4 135 ? 143.031 121.810 177.999 1.00 24.23  ? 113 THR N CG2 1 
ATOM   5945 N  N   . THR D 4 136 ? 140.191 124.339 176.691 1.00 22.94  ? 114 THR N N   1 
ATOM   5946 C  CA  . THR D 4 136 ? 139.485 125.456 177.313 1.00 17.54  ? 114 THR N CA  1 
ATOM   5947 C  C   . THR D 4 136 ? 138.438 125.948 176.322 1.00 23.83  ? 114 THR N C   1 
ATOM   5948 O  O   . THR D 4 136 ? 138.728 126.784 175.466 1.00 29.64  ? 114 THR N O   1 
ATOM   5949 C  CB  . THR D 4 136 ? 140.450 126.566 177.701 1.00 22.76  ? 114 THR N CB  1 
ATOM   5950 O  OG1 . THR D 4 136 ? 141.488 126.028 178.526 1.00 26.97  ? 114 THR N OG1 1 
ATOM   5951 C  CG2 . THR D 4 136 ? 139.723 127.654 178.470 1.00 26.03  ? 114 THR N CG2 1 
ATOM   5952 N  N   . TYR D 4 137 ? 137.224 125.426 176.438 1.00 20.65  ? 115 TYR N N   1 
ATOM   5953 C  CA  . TYR D 4 137 ? 136.105 125.824 175.601 1.00 12.22  ? 115 TYR N CA  1 
ATOM   5954 C  C   . TYR D 4 137 ? 135.079 126.535 176.468 1.00 19.33  ? 115 TYR N C   1 
ATOM   5955 O  O   . TYR D 4 137 ? 134.903 126.191 177.639 1.00 25.24  ? 115 TYR N O   1 
ATOM   5956 C  CB  . TYR D 4 137 ? 135.484 124.613 174.907 1.00 16.49  ? 115 TYR N CB  1 
ATOM   5957 C  CG  . TYR D 4 137 ? 134.433 124.952 173.883 1.00 10.07  ? 115 TYR N CG  1 
ATOM   5958 C  CD1 . TYR D 4 137 ? 134.748 125.695 172.762 1.00 13.46  ? 115 TYR N CD1 1 
ATOM   5959 C  CD2 . TYR D 4 137 ? 133.126 124.530 174.040 1.00 13.69  ? 115 TYR N CD2 1 
ATOM   5960 C  CE1 . TYR D 4 137 ? 133.795 126.004 171.830 1.00 14.19  ? 115 TYR N CE1 1 
ATOM   5961 C  CE2 . TYR D 4 137 ? 132.173 124.839 173.115 1.00 13.07  ? 115 TYR N CE2 1 
ATOM   5962 C  CZ  . TYR D 4 137 ? 132.513 125.577 172.016 1.00 11.88  ? 115 TYR N CZ  1 
ATOM   5963 O  OH  . TYR D 4 137 ? 131.561 125.882 171.091 1.00 19.23  ? 115 TYR N OH  1 
ATOM   5964 N  N   . ALA D 4 138 ? 134.407 127.529 175.891 1.00 16.73  ? 116 ALA N N   1 
ATOM   5965 C  CA  . ALA D 4 138 ? 133.620 128.476 176.671 1.00 22.51  ? 116 ALA N CA  1 
ATOM   5966 C  C   . ALA D 4 138 ? 132.155 128.095 176.817 1.00 21.97  ? 116 ALA N C   1 
ATOM   5967 O  O   . ALA D 4 138 ? 131.525 128.478 177.807 1.00 24.28  ? 116 ALA N O   1 
ATOM   5968 C  CB  . ALA D 4 138 ? 133.716 129.868 176.047 1.00 17.58  ? 116 ALA N CB  1 
ATOM   5969 N  N   . TYR D 4 139 ? 131.594 127.346 175.876 1.00 22.68  ? 117 TYR N N   1 
ATOM   5970 C  CA  . TYR D 4 139 ? 130.161 127.079 175.832 1.00 18.35  ? 117 TYR N CA  1 
ATOM   5971 C  C   . TYR D 4 139 ? 129.851 125.614 176.117 1.00 20.81  ? 117 TYR N C   1 
ATOM   5972 O  O   . TYR D 4 139 ? 129.037 124.991 175.438 1.00 17.60  ? 117 TYR N O   1 
ATOM   5973 C  CB  . TYR D 4 139 ? 129.572 127.488 174.487 1.00 12.65  ? 117 TYR N CB  1 
ATOM   5974 C  CG  . TYR D 4 139 ? 130.030 128.831 173.979 1.00 19.67  ? 117 TYR N CG  1 
ATOM   5975 C  CD1 . TYR D 4 139 ? 129.671 130.002 174.626 1.00 21.27  ? 117 TYR N CD1 1 
ATOM   5976 C  CD2 . TYR D 4 139 ? 130.810 128.931 172.841 1.00 24.09  ? 117 TYR N CD2 1 
ATOM   5977 C  CE1 . TYR D 4 139 ? 130.080 131.223 174.158 1.00 11.03  ? 117 TYR N CE1 1 
ATOM   5978 C  CE2 . TYR D 4 139 ? 131.220 130.150 172.369 1.00 21.89  ? 117 TYR N CE2 1 
ATOM   5979 C  CZ  . TYR D 4 139 ? 130.854 131.288 173.030 1.00 15.17  ? 117 TYR N CZ  1 
ATOM   5980 O  OH  . TYR D 4 139 ? 131.270 132.498 172.550 1.00 18.01  ? 117 TYR N OH  1 
ATOM   5981 N  N   . ARG D 4 140 ? 130.503 125.047 177.125 1.00 20.18  ? 118 ARG N N   1 
ATOM   5982 C  CA  . ARG D 4 140 ? 130.190 123.711 177.598 1.00 20.74  ? 118 ARG N CA  1 
ATOM   5983 C  C   . ARG D 4 140 ? 130.120 123.719 179.117 1.00 24.48  ? 118 ARG N C   1 
ATOM   5984 O  O   . ARG D 4 140 ? 130.744 124.552 179.777 1.00 32.14  ? 118 ARG N O   1 
ATOM   5985 C  CB  . ARG D 4 140 ? 131.215 122.688 177.096 1.00 29.01  ? 118 ARG N CB  1 
ATOM   5986 C  CG  . ARG D 4 140 ? 132.513 122.632 177.844 1.00 24.64  ? 118 ARG N CG  1 
ATOM   5987 C  CD  . ARG D 4 140 ? 133.227 121.333 177.543 1.00 18.26  ? 118 ARG N CD  1 
ATOM   5988 N  NE  . ARG D 4 140 ? 134.665 121.466 177.715 1.00 20.04  ? 118 ARG N NE  1 
ATOM   5989 C  CZ  . ARG D 4 140 ? 135.542 121.398 176.726 1.00 18.91  ? 118 ARG N CZ  1 
ATOM   5990 N  NH1 . ARG D 4 140 ? 135.162 121.183 175.480 1.00 17.00  ? 118 ARG N NH1 1 
ATOM   5991 N  NH2 . ARG D 4 140 ? 136.833 121.551 176.995 1.00 19.14  ? 118 ARG N NH2 1 
ATOM   5992 N  N   . GLY D 4 141 ? 129.340 122.793 179.667 1.00 20.41  ? 119 GLY N N   1 
ATOM   5993 C  CA  . GLY D 4 141 ? 129.083 122.772 181.093 1.00 23.86  ? 119 GLY N CA  1 
ATOM   5994 C  C   . GLY D 4 141 ? 130.262 122.357 181.949 1.00 33.56  ? 119 GLY N C   1 
ATOM   5995 O  O   . GLY D 4 141 ? 131.411 122.400 181.503 1.00 31.40  ? 119 GLY N O   1 
ATOM   5996 N  N   . GLN D 4 142 ? 129.988 121.955 183.191 1.00 46.37  ? 120 GLN N N   1 
ATOM   5997 C  CA  . GLN D 4 142 ? 131.032 121.496 184.098 1.00 45.42  ? 120 GLN N CA  1 
ATOM   5998 C  C   . GLN D 4 142 ? 131.145 119.979 184.172 1.00 48.36  ? 120 GLN N C   1 
ATOM   5999 O  O   . GLN D 4 142 ? 132.181 119.476 184.616 1.00 47.03  ? 120 GLN N O   1 
ATOM   6000 C  CB  . GLN D 4 142 ? 130.798 122.051 185.505 1.00 45.72  ? 120 GLN N CB  1 
ATOM   6001 C  CG  . GLN D 4 142 ? 130.728 123.562 185.559 1.00 52.75  ? 120 GLN N CG  1 
ATOM   6002 C  CD  . GLN D 4 142 ? 132.024 124.193 186.019 1.00 55.66  ? 120 GLN N CD  1 
ATOM   6003 O  OE1 . GLN D 4 142 ? 133.085 123.575 185.955 1.00 55.35  ? 120 GLN N OE1 1 
ATOM   6004 N  NE2 . GLN D 4 142 ? 131.945 125.433 186.488 1.00 51.80  ? 120 GLN N NE2 1 
ATOM   6005 N  N   . GLY D 4 143 ? 130.119 119.247 183.756 1.00 46.89  ? 121 GLY N N   1 
ATOM   6006 C  CA  . GLY D 4 143 ? 130.199 117.812 183.600 1.00 42.57  ? 121 GLY N CA  1 
ATOM   6007 C  C   . GLY D 4 143 ? 129.697 117.059 184.820 1.00 45.77  ? 121 GLY N C   1 
ATOM   6008 O  O   . GLY D 4 143 ? 129.559 117.603 185.917 1.00 45.60  ? 121 GLY N O   1 
ATOM   6009 N  N   . THR D 4 144 ? 129.407 115.774 184.607 1.00 49.62  ? 122 THR N N   1 
ATOM   6010 C  CA  . THR D 4 144 ? 129.022 114.855 185.671 1.00 49.52  ? 122 THR N CA  1 
ATOM   6011 C  C   . THR D 4 144 ? 129.838 113.577 185.558 1.00 48.00  ? 122 THR N C   1 
ATOM   6012 O  O   . THR D 4 144 ? 130.129 113.113 184.454 1.00 49.42  ? 122 THR N O   1 
ATOM   6013 C  CB  . THR D 4 144 ? 127.523 114.517 185.626 1.00 47.89  ? 122 THR N CB  1 
ATOM   6014 O  OG1 . THR D 4 144 ? 127.196 113.900 184.377 1.00 44.56  ? 122 THR N OG1 1 
ATOM   6015 C  CG2 . THR D 4 144 ? 126.690 115.768 185.793 1.00 49.67  ? 122 THR N CG2 1 
ATOM   6016 N  N   . GLN D 4 145 ? 130.205 113.011 186.703 1.00 53.96  ? 123 GLN N N   1 
ATOM   6017 C  CA  . GLN D 4 145 ? 131.034 111.814 186.727 1.00 56.70  ? 123 GLN N CA  1 
ATOM   6018 C  C   . GLN D 4 145 ? 130.182 110.562 186.584 1.00 56.31  ? 123 GLN N C   1 
ATOM   6019 O  O   . GLN D 4 145 ? 129.108 110.453 187.180 1.00 56.45  ? 123 GLN N O   1 
ATOM   6020 C  CB  . GLN D 4 145 ? 131.834 111.746 188.026 1.00 52.28  ? 123 GLN N CB  1 
ATOM   6021 C  CG  . GLN D 4 145 ? 132.619 110.466 188.209 1.00 49.24  ? 123 GLN N CG  1 
ATOM   6022 C  CD  . GLN D 4 145 ? 134.013 110.556 187.632 1.00 55.54  ? 123 GLN N CD  1 
ATOM   6023 O  OE1 . GLN D 4 145 ? 134.696 111.567 187.778 1.00 59.02  ? 123 GLN N OE1 1 
ATOM   6024 N  NE2 . GLN D 4 145 ? 134.443 109.495 186.968 1.00 56.20  ? 123 GLN N NE2 1 
ATOM   6025 N  N   . VAL D 4 146 ? 130.667 109.613 185.785 1.00 57.30  ? 124 VAL N N   1 
ATOM   6026 C  CA  . VAL D 4 146 ? 130.024 108.319 185.607 1.00 57.76  ? 124 VAL N CA  1 
ATOM   6027 C  C   . VAL D 4 146 ? 131.067 107.244 185.873 1.00 60.85  ? 124 VAL N C   1 
ATOM   6028 O  O   . VAL D 4 146 ? 132.093 107.186 185.182 1.00 61.26  ? 124 VAL N O   1 
ATOM   6029 C  CB  . VAL D 4 146 ? 129.427 108.160 184.201 1.00 57.76  ? 124 VAL N CB  1 
ATOM   6030 C  CG1 . VAL D 4 146 ? 128.896 106.757 184.012 1.00 59.29  ? 124 VAL N CG1 1 
ATOM   6031 C  CG2 . VAL D 4 146 ? 128.330 109.177 183.975 1.00 56.23  ? 124 VAL N CG2 1 
ATOM   6032 N  N   . THR D 4 147 ? 130.809 106.401 186.870 1.00 65.01  ? 125 THR N N   1 
ATOM   6033 C  CA  . THR D 4 147 ? 131.688 105.302 187.240 1.00 65.27  ? 125 THR N CA  1 
ATOM   6034 C  C   . THR D 4 147 ? 130.960 103.989 187.008 1.00 66.44  ? 125 THR N C   1 
ATOM   6035 O  O   . THR D 4 147 ? 129.815 103.829 187.438 1.00 70.58  ? 125 THR N O   1 
ATOM   6036 C  CB  . THR D 4 147 ? 132.118 105.403 188.704 1.00 66.84  ? 125 THR N CB  1 
ATOM   6037 O  OG1 . THR D 4 147 ? 132.433 106.764 189.020 1.00 67.11  ? 125 THR N OG1 1 
ATOM   6038 C  CG2 . THR D 4 147 ? 133.333 104.534 188.963 1.00 65.61  ? 125 THR N CG2 1 
ATOM   6039 N  N   . VAL D 4 148 ? 131.617 103.057 186.328 1.00 65.88  ? 126 VAL N N   1 
ATOM   6040 C  CA  . VAL D 4 148 ? 131.017 101.757 186.058 1.00 68.42  ? 126 VAL N CA  1 
ATOM   6041 C  C   . VAL D 4 148 ? 131.928 100.640 186.548 1.00 68.04  ? 126 VAL N C   1 
ATOM   6042 O  O   . VAL D 4 148 ? 131.750 100.119 187.650 1.00 68.21  ? 126 VAL N O   1 
ATOM   6043 C  CB  . VAL D 4 148 ? 130.709 101.584 184.565 1.00 68.94  ? 126 VAL N CB  1 
ATOM   6044 C  CG1 . VAL D 4 148 ? 130.050 100.245 184.322 1.00 67.18  ? 126 VAL N CG1 1 
ATOM   6045 C  CG2 . VAL D 4 148 ? 129.824 102.710 184.070 1.00 67.84  ? 126 VAL N CG2 1 
ATOM   6046 N  N   . SER E 5 1   ? 125.300 153.848 85.155  1.00 113.78 ? 1   SER L N   1 
ATOM   6047 C  CA  . SER E 5 1   ? 124.950 154.268 86.506  1.00 115.14 ? 1   SER L CA  1 
ATOM   6048 C  C   . SER E 5 1   ? 125.475 153.286 87.547  1.00 115.35 ? 1   SER L C   1 
ATOM   6049 O  O   . SER E 5 1   ? 125.227 152.084 87.459  1.00 114.78 ? 1   SER L O   1 
ATOM   6050 C  CB  . SER E 5 1   ? 123.433 154.413 86.645  1.00 115.69 ? 1   SER L CB  1 
ATOM   6051 O  OG  . SER E 5 1   ? 123.070 154.707 87.982  1.00 115.60 ? 1   SER L OG  1 
ATOM   6052 N  N   . TYR E 5 2   ? 126.202 153.804 88.534  1.00 109.28 ? 2   TYR L N   1 
ATOM   6053 C  CA  . TYR E 5 2   ? 126.734 152.990 89.621  1.00 108.21 ? 2   TYR L CA  1 
ATOM   6054 C  C   . TYR E 5 2   ? 125.706 152.950 90.745  1.00 109.61 ? 2   TYR L C   1 
ATOM   6055 O  O   . TYR E 5 2   ? 125.538 153.930 91.479  1.00 110.03 ? 2   TYR L O   1 
ATOM   6056 C  CB  . TYR E 5 2   ? 128.068 153.545 90.113  1.00 107.41 ? 2   TYR L CB  1 
ATOM   6057 C  CG  . TYR E 5 2   ? 128.682 152.760 91.253  1.00 107.97 ? 2   TYR L CG  1 
ATOM   6058 C  CD1 . TYR E 5 2   ? 129.545 151.702 91.008  1.00 107.83 ? 2   TYR L CD1 1 
ATOM   6059 C  CD2 . TYR E 5 2   ? 128.398 153.078 92.574  1.00 108.20 ? 2   TYR L CD2 1 
ATOM   6060 C  CE1 . TYR E 5 2   ? 130.105 150.983 92.047  1.00 107.98 ? 2   TYR L CE1 1 
ATOM   6061 C  CE2 . TYR E 5 2   ? 128.951 152.365 93.616  1.00 107.46 ? 2   TYR L CE2 1 
ATOM   6062 C  CZ  . TYR E 5 2   ? 129.804 151.320 93.349  1.00 106.45 ? 2   TYR L CZ  1 
ATOM   6063 O  OH  . TYR E 5 2   ? 130.355 150.612 94.389  1.00 104.29 ? 2   TYR L OH  1 
ATOM   6064 N  N   . SER E 5 3   ? 125.018 151.821 90.880  1.00 109.98 ? 3   SER L N   1 
ATOM   6065 C  CA  . SER E 5 3   ? 124.050 151.633 91.949  1.00 108.55 ? 3   SER L CA  1 
ATOM   6066 C  C   . SER E 5 3   ? 124.717 150.985 93.155  1.00 107.94 ? 3   SER L C   1 
ATOM   6067 O  O   . SER E 5 3   ? 125.545 150.080 93.013  1.00 106.91 ? 3   SER L O   1 
ATOM   6068 C  CB  . SER E 5 3   ? 122.877 150.775 91.473  1.00 107.52 ? 3   SER L CB  1 
ATOM   6069 O  OG  . SER E 5 3   ? 122.548 151.068 90.127  1.00 107.11 ? 3   SER L OG  1 
ATOM   6070 N  N   . MET E 5 4   ? 124.355 151.460 94.341  1.00 99.25  ? 4   MET L N   1 
ATOM   6071 C  CA  . MET E 5 4   ? 124.900 150.931 95.579  1.00 97.08  ? 4   MET L CA  1 
ATOM   6072 C  C   . MET E 5 4   ? 124.068 149.739 96.038  1.00 97.79  ? 4   MET L C   1 
ATOM   6073 O  O   . MET E 5 4   ? 122.855 149.683 95.824  1.00 98.55  ? 4   MET L O   1 
ATOM   6074 C  CB  . MET E 5 4   ? 124.933 152.021 96.655  1.00 95.96  ? 4   MET L CB  1 
ATOM   6075 C  CG  . MET E 5 4   ? 125.670 151.630 97.923  1.00 97.64  ? 4   MET L CG  1 
ATOM   6076 S  SD  . MET E 5 4   ? 125.014 152.343 99.443  1.00 102.68 ? 4   MET L SD  1 
ATOM   6077 C  CE  . MET E 5 4   ? 125.822 153.933 99.453  1.00 97.27  ? 4   MET L CE  1 
ATOM   6078 N  N   . GLU E 5 5   ? 124.741 148.768 96.654  1.00 87.55  ? 5   GLU L N   1 
ATOM   6079 C  CA  . GLU E 5 5   ? 124.094 147.540 97.100  1.00 82.87  ? 5   GLU L CA  1 
ATOM   6080 C  C   . GLU E 5 5   ? 124.449 147.264 98.555  1.00 83.67  ? 5   GLU L C   1 
ATOM   6081 O  O   . GLU E 5 5   ? 125.011 148.131 99.229  1.00 86.10  ? 5   GLU L O   1 
ATOM   6082 C  CB  . GLU E 5 5   ? 124.491 146.369 96.200  1.00 83.35  ? 5   GLU L CB  1 
ATOM   6083 C  CG  . GLU E 5 5   ? 124.132 146.584 94.736  1.00 85.08  ? 5   GLU L CG  1 
ATOM   6084 C  CD  . GLU E 5 5   ? 124.102 145.298 93.937  1.00 86.65  ? 5   GLU L CD  1 
ATOM   6085 O  OE1 . GLU E 5 5   ? 123.218 144.455 94.194  1.00 86.30  ? 5   GLU L OE1 1 
ATOM   6086 O  OE2 . GLU E 5 5   ? 124.962 145.132 93.047  1.00 87.07  ? 5   GLU L OE2 1 
ATOM   6087 N  N   . HIS E 5 6   ? 124.123 146.076 99.059  1.00 71.99  ? 6   HIS L N   1 
ATOM   6088 C  CA  . HIS E 5 6   ? 124.228 145.830 100.491 1.00 69.66  ? 6   HIS L CA  1 
ATOM   6089 C  C   . HIS E 5 6   ? 125.605 145.370 100.945 1.00 67.80  ? 6   HIS L C   1 
ATOM   6090 O  O   . HIS E 5 6   ? 125.919 145.513 102.131 1.00 71.33  ? 6   HIS L O   1 
ATOM   6091 C  CB  . HIS E 5 6   ? 123.178 144.812 100.929 1.00 69.27  ? 6   HIS L CB  1 
ATOM   6092 C  CG  . HIS E 5 6   ? 121.953 145.442 101.504 1.00 69.59  ? 6   HIS L CG  1 
ATOM   6093 N  ND1 . HIS E 5 6   ? 120.709 145.300 100.931 1.00 71.68  ? 6   HIS L ND1 1 
ATOM   6094 C  CD2 . HIS E 5 6   ? 121.772 146.188 102.618 1.00 68.02  ? 6   HIS L CD2 1 
ATOM   6095 C  CE1 . HIS E 5 6   ? 119.816 145.945 101.659 1.00 71.39  ? 6   HIS L CE1 1 
ATOM   6096 N  NE2 . HIS E 5 6   ? 120.436 146.493 102.688 1.00 69.86  ? 6   HIS L NE2 1 
ATOM   6097 N  N   . PHE E 5 7   ? 126.426 144.836 100.049 1.00 63.40  ? 7   PHE L N   1 
ATOM   6098 C  CA  . PHE E 5 7   ? 127.807 144.480 100.354 1.00 62.68  ? 7   PHE L CA  1 
ATOM   6099 C  C   . PHE E 5 7   ? 128.441 144.013 99.054  1.00 66.23  ? 7   PHE L C   1 
ATOM   6100 O  O   . PHE E 5 7   ? 127.748 143.748 98.069  1.00 71.82  ? 7   PHE L O   1 
ATOM   6101 C  CB  . PHE E 5 7   ? 127.895 143.403 101.439 1.00 67.55  ? 7   PHE L CB  1 
ATOM   6102 C  CG  . PHE E 5 7   ? 129.267 143.220 102.012 1.00 64.25  ? 7   PHE L CG  1 
ATOM   6103 C  CD1 . PHE E 5 7   ? 130.111 144.292 102.185 1.00 64.90  ? 7   PHE L CD1 1 
ATOM   6104 C  CD2 . PHE E 5 7   ? 129.709 141.966 102.383 1.00 64.75  ? 7   PHE L CD2 1 
ATOM   6105 C  CE1 . PHE E 5 7   ? 131.371 144.114 102.710 1.00 67.86  ? 7   PHE L CE1 1 
ATOM   6106 C  CE2 . PHE E 5 7   ? 130.964 141.785 102.905 1.00 64.96  ? 7   PHE L CE2 1 
ATOM   6107 C  CZ  . PHE E 5 7   ? 131.795 142.858 103.069 1.00 67.28  ? 7   PHE L CZ  1 
ATOM   6108 N  N   . ARG E 5 8   ? 129.724 143.882 99.068  1.00 65.96  ? 8   ARG L N   1 
ATOM   6109 C  CA  . ARG E 5 8   ? 130.296 143.571 97.834  1.00 68.03  ? 8   ARG L CA  1 
ATOM   6110 C  C   . ARG E 5 8   ? 130.269 142.093 97.635  1.00 70.31  ? 8   ARG L C   1 
ATOM   6111 O  O   . ARG E 5 8   ? 130.096 141.366 98.571  1.00 69.64  ? 8   ARG L O   1 
ATOM   6112 C  CB  . ARG E 5 8   ? 131.657 144.202 97.766  1.00 68.31  ? 8   ARG L CB  1 
ATOM   6113 C  CG  . ARG E 5 8   ? 131.593 145.706 97.758  1.00 70.96  ? 8   ARG L CG  1 
ATOM   6114 C  CD  . ARG E 5 8   ? 132.970 146.290 97.615  1.00 69.32  ? 8   ARG L CD  1 
ATOM   6115 N  NE  . ARG E 5 8   ? 132.960 147.741 97.626  1.00 69.71  ? 8   ARG L NE  1 
ATOM   6116 C  CZ  . ARG E 5 8   ? 132.710 148.499 96.573  1.00 69.14  ? 8   ARG L CZ  1 
ATOM   6117 N  NH1 . ARG E 5 8   ? 132.450 147.959 95.404  1.00 70.40  ? 8   ARG L NH1 1 
ATOM   6118 N  NH2 . ARG E 5 8   ? 132.718 149.809 96.698  1.00 73.40  ? 8   ARG L NH2 1 
ATOM   6119 N  N   . TRP E 5 9   ? 130.333 141.644 96.406  1.00 66.99  ? 9   TRP L N   1 
ATOM   6120 C  CA  . TRP E 5 9   ? 130.390 140.256 96.066  1.00 64.67  ? 9   TRP L CA  1 
ATOM   6121 C  C   . TRP E 5 9   ? 129.059 139.547 96.027  1.00 65.79  ? 9   TRP L C   1 
ATOM   6122 O  O   . TRP E 5 9   ? 129.013 138.361 96.162  1.00 68.49  ? 9   TRP L O   1 
ATOM   6123 C  CB  . TRP E 5 9   ? 131.327 139.603 97.000  1.00 65.88  ? 9   TRP L CB  1 
ATOM   6124 C  CG  . TRP E 5 9   ? 132.661 140.134 96.982  1.00 68.69  ? 9   TRP L CG  1 
ATOM   6125 C  CD1 . TRP E 5 9   ? 133.470 140.273 95.910  1.00 67.70  ? 9   TRP L CD1 1 
ATOM   6126 C  CD2 . TRP E 5 9   ? 133.393 140.587 98.109  1.00 69.69  ? 9   TRP L CD2 1 
ATOM   6127 N  NE1 . TRP E 5 9   ? 134.668 140.805 96.296  1.00 67.19  ? 9   TRP L NE1 1 
ATOM   6128 C  CE2 . TRP E 5 9   ? 134.640 141.011 97.648  1.00 67.36  ? 9   TRP L CE2 1 
ATOM   6129 C  CE3 . TRP E 5 9   ? 133.107 140.686 99.466  1.00 66.03  ? 9   TRP L CE3 1 
ATOM   6130 C  CZ2 . TRP E 5 9   ? 135.595 141.518 98.487  1.00 65.90  ? 9   TRP L CZ2 1 
ATOM   6131 C  CZ3 . TRP E 5 9   ? 134.043 141.190 100.287 1.00 65.16  ? 9   TRP L CZ3 1 
ATOM   6132 C  CH2 . TRP E 5 9   ? 135.279 141.601 99.804  1.00 66.98  ? 9   TRP L CH2 1 
ATOM   6133 N  N   . GLY E 5 10  ? 127.988 140.248 95.760  1.00 65.85  ? 10  GLY L N   1 
ATOM   6134 C  CA  . GLY E 5 10  ? 126.696 139.645 95.699  1.00 65.93  ? 10  GLY L CA  1 
ATOM   6135 C  C   . GLY E 5 10  ? 126.196 139.216 94.363  1.00 67.31  ? 10  GLY L C   1 
ATOM   6136 O  O   . GLY E 5 10  ? 125.046 138.824 94.239  1.00 70.10  ? 10  GLY L O   1 
ATOM   6137 N  N   . LYS E 5 11  ? 127.040 139.259 93.351  1.00 70.15  ? 11  LYS L N   1 
ATOM   6138 C  CA  . LYS E 5 11  ? 126.674 138.808 92.019  1.00 72.29  ? 11  LYS L CA  1 
ATOM   6139 C  C   . LYS E 5 11  ? 127.953 138.548 91.350  1.00 72.28  ? 11  LYS L C   1 
ATOM   6140 O  O   . LYS E 5 11  ? 128.943 139.199 91.631  1.00 71.10  ? 11  LYS L O   1 
ATOM   6141 C  CB  . LYS E 5 11  ? 125.938 139.862 91.240  1.00 72.58  ? 11  LYS L CB  1 
ATOM   6142 C  CG  . LYS E 5 11  ? 124.562 140.213 91.774  1.00 71.31  ? 11  LYS L CG  1 
ATOM   6143 C  CD  . LYS E 5 11  ? 123.907 141.300 90.939  1.00 72.27  ? 11  LYS L CD  1 
ATOM   6144 C  CE  . LYS E 5 11  ? 122.521 141.633 91.459  1.00 69.89  ? 11  LYS L CE  1 
ATOM   6145 N  NZ  . LYS E 5 11  ? 121.877 142.711 90.670  1.00 68.87  ? 11  LYS L NZ  1 
ATOM   6146 N  N   . PRO E 5 12  ? 127.965 137.582 90.451  1.00 72.73  ? 12  PRO L N   1 
ATOM   6147 C  CA  . PRO E 5 12  ? 129.249 137.244 89.866  1.00 73.12  ? 12  PRO L CA  1 
ATOM   6148 C  C   . PRO E 5 12  ? 129.642 138.302 88.893  1.00 73.95  ? 12  PRO L C   1 
ATOM   6149 O  O   . PRO E 5 12  ? 129.440 138.089 87.710  1.00 71.28  ? 12  PRO L O   1 
ATOM   6150 C  CB  . PRO E 5 12  ? 128.959 135.970 89.104  1.00 73.75  ? 12  PRO L CB  1 
ATOM   6151 C  CG  . PRO E 5 12  ? 127.600 135.519 89.519  1.00 74.99  ? 12  PRO L CG  1 
ATOM   6152 C  CD  . PRO E 5 12  ? 126.876 136.754 89.926  1.00 73.53  ? 12  PRO L CD  1 
ATOM   6153 N  N   . VAL E 5 13  ? 130.177 139.426 89.348  1.00 83.10  ? 13  VAL L N   1 
ATOM   6154 C  CA  . VAL E 5 13  ? 130.672 140.469 88.428  1.00 84.32  ? 13  VAL L CA  1 
ATOM   6155 C  C   . VAL E 5 13  ? 131.919 140.054 87.641  1.00 83.79  ? 13  VAL L C   1 
ATOM   6156 O  O   . VAL E 5 13  ? 131.819 139.550 86.524  1.00 83.24  ? 13  VAL L O   1 
ATOM   6157 C  CB  . VAL E 5 13  ? 131.006 141.787 89.158  1.00 83.94  ? 13  VAL L CB  1 
ATOM   6158 C  CG1 . VAL E 5 13  ? 132.026 142.586 88.367  1.00 82.92  ? 13  VAL L CG1 1 
ATOM   6159 C  CG2 . VAL E 5 13  ? 129.747 142.601 89.393  1.00 82.26  ? 13  VAL L CG2 1 
ATOM   6160 N  N   . GLU F 6 15  ? 151.946 171.398 144.227 1.00 122.33 ? 15  GLU A N   1 
ATOM   6161 C  CA  . GLU F 6 15  ? 152.050 170.224 145.084 1.00 125.11 ? 15  GLU A CA  1 
ATOM   6162 C  C   . GLU F 6 15  ? 151.216 169.074 144.532 1.00 124.50 ? 15  GLU A C   1 
ATOM   6163 O  O   . GLU F 6 15  ? 151.442 167.915 144.873 1.00 124.78 ? 15  GLU A O   1 
ATOM   6164 C  CB  . GLU F 6 15  ? 151.614 170.558 146.513 1.00 125.31 ? 15  GLU A CB  1 
ATOM   6165 C  CG  . GLU F 6 15  ? 150.181 170.172 146.837 1.00 123.90 ? 15  GLU A CG  1 
ATOM   6166 C  CD  . GLU F 6 15  ? 149.187 171.258 146.485 1.00 126.98 ? 15  GLU A CD  1 
ATOM   6167 O  OE1 . GLU F 6 15  ? 149.523 172.139 145.665 1.00 129.00 ? 15  GLU A OE1 1 
ATOM   6168 O  OE2 . GLU F 6 15  ? 148.065 171.233 147.030 1.00 127.64 ? 15  GLU A OE2 1 
ATOM   6169 N  N   . GLU F 6 16  ? 150.241 169.403 143.681 1.00 119.82 ? 16  GLU A N   1 
ATOM   6170 C  CA  . GLU F 6 16  ? 149.464 168.361 143.019 1.00 117.32 ? 16  GLU A CA  1 
ATOM   6171 C  C   . GLU F 6 16  ? 150.324 167.573 142.042 1.00 116.91 ? 16  GLU A C   1 
ATOM   6172 O  O   . GLU F 6 16  ? 150.101 166.376 141.835 1.00 117.86 ? 16  GLU A O   1 
ATOM   6173 C  CB  . GLU F 6 16  ? 148.262 168.972 142.301 1.00 116.92 ? 16  GLU A CB  1 
ATOM   6174 C  CG  . GLU F 6 16  ? 147.211 169.550 143.227 1.00 118.13 ? 16  GLU A CG  1 
ATOM   6175 C  CD  . GLU F 6 16  ? 146.199 168.516 143.669 1.00 120.56 ? 16  GLU A CD  1 
ATOM   6176 O  OE1 . GLU F 6 16  ? 145.339 168.138 142.849 1.00 120.34 ? 16  GLU A OE1 1 
ATOM   6177 O  OE2 . GLU F 6 16  ? 146.261 168.084 144.838 1.00 120.08 ? 16  GLU A OE2 1 
ATOM   6178 N  N   . LYS F 6 17  ? 151.305 168.232 141.422 1.00 113.59 ? 17  LYS A N   1 
ATOM   6179 C  CA  . LYS F 6 17  ? 152.219 167.522 140.534 1.00 112.52 ? 17  LYS A CA  1 
ATOM   6180 C  C   . LYS F 6 17  ? 153.047 166.499 141.300 1.00 113.34 ? 17  LYS A C   1 
ATOM   6181 O  O   . LYS F 6 17  ? 153.228 165.366 140.837 1.00 113.88 ? 17  LYS A O   1 
ATOM   6182 C  CB  . LYS F 6 17  ? 153.125 168.519 139.811 1.00 111.90 ? 17  LYS A CB  1 
ATOM   6183 N  N   . ALA F 6 18  ? 153.552 166.875 142.477 1.00 104.27 ? 18  ALA A N   1 
ATOM   6184 C  CA  . ALA F 6 18  ? 154.329 165.938 143.279 1.00 105.50 ? 18  ALA A CA  1 
ATOM   6185 C  C   . ALA F 6 18  ? 153.479 164.771 143.763 1.00 103.42 ? 18  ALA A C   1 
ATOM   6186 O  O   . ALA F 6 18  ? 153.949 163.627 143.781 1.00 102.33 ? 18  ALA A O   1 
ATOM   6187 C  CB  . ALA F 6 18  ? 154.965 166.663 144.463 1.00 105.31 ? 18  ALA A CB  1 
ATOM   6188 N  N   . GLN F 6 19  ? 152.235 165.037 144.162 1.00 89.39  ? 19  GLN A N   1 
ATOM   6189 C  CA  . GLN F 6 19  ? 151.350 163.960 144.584 1.00 87.02  ? 19  GLN A CA  1 
ATOM   6190 C  C   . GLN F 6 19  ? 151.027 163.027 143.425 1.00 92.36  ? 19  GLN A C   1 
ATOM   6191 O  O   . GLN F 6 19  ? 150.987 161.802 143.598 1.00 98.38  ? 19  GLN A O   1 
ATOM   6192 C  CB  . GLN F 6 19  ? 150.074 164.539 145.187 1.00 86.47  ? 19  GLN A CB  1 
ATOM   6193 C  CG  . GLN F 6 19  ? 149.377 163.607 146.160 1.00 91.15  ? 19  GLN A CG  1 
ATOM   6194 C  CD  . GLN F 6 19  ? 148.189 164.252 146.834 1.00 92.26  ? 19  GLN A CD  1 
ATOM   6195 O  OE1 . GLN F 6 19  ? 147.212 163.584 147.164 1.00 94.48  ? 19  GLN A OE1 1 
ATOM   6196 N  NE2 . GLN F 6 19  ? 148.264 165.559 147.041 1.00 91.45  ? 19  GLN A NE2 1 
ATOM   6197 N  N   . ARG F 6 20  ? 150.803 163.585 142.234 1.00 87.52  ? 20  ARG A N   1 
ATOM   6198 C  CA  . ARG F 6 20  ? 150.567 162.753 141.059 1.00 81.96  ? 20  ARG A CA  1 
ATOM   6199 C  C   . ARG F 6 20  ? 151.783 161.893 140.744 1.00 83.79  ? 20  ARG A C   1 
ATOM   6200 O  O   . ARG F 6 20  ? 151.646 160.721 140.381 1.00 88.85  ? 20  ARG A O   1 
ATOM   6201 C  CB  . ARG F 6 20  ? 150.209 163.630 139.861 1.00 90.71  ? 20  ARG A CB  1 
ATOM   6202 C  CG  . ARG F 6 20  ? 148.758 164.095 139.811 1.00 91.54  ? 20  ARG A CG  1 
ATOM   6203 C  CD  . ARG F 6 20  ? 147.786 162.983 140.159 1.00 91.80  ? 20  ARG A CD  1 
ATOM   6204 N  NE  . ARG F 6 20  ? 147.901 161.847 139.250 1.00 94.77  ? 20  ARG A NE  1 
ATOM   6205 C  CZ  . ARG F 6 20  ? 147.011 160.869 139.159 1.00 95.53  ? 20  ARG A CZ  1 
ATOM   6206 N  NH1 . ARG F 6 20  ? 145.914 160.859 139.901 1.00 92.29  ? 20  ARG A NH1 1 
ATOM   6207 N  NH2 . ARG F 6 20  ? 147.227 159.872 138.305 1.00 93.63  ? 20  ARG A NH2 1 
ATOM   6208 N  N   . GLU F 6 21  ? 152.984 162.458 140.876 1.00 83.92  ? 21  GLU A N   1 
ATOM   6209 C  CA  . GLU F 6 21  ? 154.196 161.683 140.625 1.00 85.49  ? 21  GLU A CA  1 
ATOM   6210 C  C   . GLU F 6 21  ? 154.356 160.549 141.631 1.00 87.50  ? 21  GLU A C   1 
ATOM   6211 O  O   . GLU F 6 21  ? 154.713 159.422 141.259 1.00 91.14  ? 21  GLU A O   1 
ATOM   6212 C  CB  . GLU F 6 21  ? 155.417 162.601 140.654 1.00 85.54  ? 21  GLU A CB  1 
ATOM   6213 C  CG  . GLU F 6 21  ? 156.660 162.008 140.014 1.00 86.99  ? 21  GLU A CG  1 
ATOM   6214 C  CD  . GLU F 6 21  ? 156.648 162.089 138.496 1.00 93.32  ? 21  GLU A CD  1 
ATOM   6215 O  OE1 . GLU F 6 21  ? 155.585 162.384 137.910 1.00 93.42  ? 21  GLU A OE1 1 
ATOM   6216 O  OE2 . GLU F 6 21  ? 157.712 161.857 137.887 1.00 92.08  ? 21  GLU A OE2 1 
ATOM   6217 N  N   . ALA F 6 22  ? 154.106 160.828 142.911 1.00 85.05  ? 22  ALA A N   1 
ATOM   6218 C  CA  . ALA F 6 22  ? 154.205 159.780 143.922 1.00 79.58  ? 22  ALA A CA  1 
ATOM   6219 C  C   . ALA F 6 22  ? 153.192 158.674 143.666 1.00 76.44  ? 22  ALA A C   1 
ATOM   6220 O  O   . ALA F 6 22  ? 153.512 157.485 143.791 1.00 83.23  ? 22  ALA A O   1 
ATOM   6221 C  CB  . ALA F 6 22  ? 154.014 160.373 145.314 1.00 82.74  ? 22  ALA A CB  1 
ATOM   6222 N  N   . ASN F 6 23  ? 151.965 159.045 143.296 1.00 69.65  ? 23  ASN A N   1 
ATOM   6223 C  CA  . ASN F 6 23  ? 150.970 158.042 142.938 1.00 69.19  ? 23  ASN A CA  1 
ATOM   6224 C  C   . ASN F 6 23  ? 151.419 157.225 141.735 1.00 76.82  ? 23  ASN A C   1 
ATOM   6225 O  O   . ASN F 6 23  ? 151.178 156.015 141.676 1.00 83.56  ? 23  ASN A O   1 
ATOM   6226 C  CB  . ASN F 6 23  ? 149.629 158.713 142.660 1.00 72.09  ? 23  ASN A CB  1 
ATOM   6227 C  CG  . ASN F 6 23  ? 148.497 157.724 142.550 1.00 75.18  ? 23  ASN A CG  1 
ATOM   6228 O  OD1 . ASN F 6 23  ? 148.682 156.531 142.750 1.00 76.90  ? 23  ASN A OD1 1 
ATOM   6229 N  ND2 . ASN F 6 23  ? 147.314 158.217 142.226 1.00 79.92  ? 23  ASN A ND2 1 
ATOM   6230 N  N   . LYS F 6 24  ? 152.065 157.867 140.759 1.00 77.20  ? 24  LYS A N   1 
ATOM   6231 C  CA  . LYS F 6 24  ? 152.565 157.136 139.598 1.00 77.28  ? 24  LYS A CA  1 
ATOM   6232 C  C   . LYS F 6 24  ? 153.598 156.092 140.000 1.00 77.11  ? 24  LYS A C   1 
ATOM   6233 O  O   . LYS F 6 24  ? 153.549 154.949 139.531 1.00 84.26  ? 24  LYS A O   1 
ATOM   6234 C  CB  . LYS F 6 24  ? 153.165 158.104 138.582 1.00 78.87  ? 24  LYS A CB  1 
ATOM   6235 C  CG  . LYS F 6 24  ? 152.141 158.886 137.788 1.00 83.15  ? 24  LYS A CG  1 
ATOM   6236 C  CD  . LYS F 6 24  ? 151.266 157.965 136.961 1.00 82.70  ? 24  LYS A CD  1 
ATOM   6237 C  CE  . LYS F 6 24  ? 150.288 158.758 136.116 1.00 83.50  ? 24  LYS A CE  1 
ATOM   6238 N  NZ  . LYS F 6 24  ? 149.327 157.870 135.408 1.00 85.30  ? 24  LYS A NZ  1 
ATOM   6239 N  N   . LYS F 6 25  ? 154.547 156.466 140.861 1.00 67.26  ? 25  LYS A N   1 
ATOM   6240 C  CA  . LYS F 6 25  ? 155.545 155.494 141.304 1.00 68.14  ? 25  LYS A CA  1 
ATOM   6241 C  C   . LYS F 6 25  ? 154.897 154.343 142.067 1.00 70.07  ? 25  LYS A C   1 
ATOM   6242 O  O   . LYS F 6 25  ? 155.232 153.168 141.848 1.00 71.89  ? 25  LYS A O   1 
ATOM   6243 C  CB  . LYS F 6 25  ? 156.606 156.176 142.165 1.00 72.32  ? 25  LYS A CB  1 
ATOM   6244 C  CG  . LYS F 6 25  ? 157.787 156.715 141.386 1.00 77.73  ? 25  LYS A CG  1 
ATOM   6245 C  CD  . LYS F 6 25  ? 157.526 158.119 140.880 1.00 78.10  ? 25  LYS A CD  1 
ATOM   6246 C  CE  . LYS F 6 25  ? 158.583 158.556 139.886 1.00 75.88  ? 25  LYS A CE  1 
ATOM   6247 N  NZ  . LYS F 6 25  ? 158.577 157.701 138.672 1.00 78.18  ? 25  LYS A NZ  1 
ATOM   6248 N  N   . ILE F 6 26  ? 153.956 154.662 142.960 1.00 70.99  ? 26  ILE A N   1 
ATOM   6249 C  CA  . ILE F 6 26  ? 153.289 153.621 143.738 1.00 65.06  ? 26  ILE A CA  1 
ATOM   6250 C  C   . ILE F 6 26  ? 152.562 152.657 142.810 1.00 67.02  ? 26  ILE A C   1 
ATOM   6251 O  O   . ILE F 6 26  ? 152.653 151.434 142.960 1.00 73.45  ? 26  ILE A O   1 
ATOM   6252 C  CB  . ILE F 6 26  ? 152.329 154.246 144.765 1.00 70.93  ? 26  ILE A CB  1 
ATOM   6253 C  CG1 . ILE F 6 26  ? 153.083 155.087 145.794 1.00 69.55  ? 26  ILE A CG1 1 
ATOM   6254 C  CG2 . ILE F 6 26  ? 151.559 153.168 145.480 1.00 73.91  ? 26  ILE A CG2 1 
ATOM   6255 C  CD1 . ILE F 6 26  ? 154.246 154.383 146.417 1.00 71.29  ? 26  ILE A CD1 1 
ATOM   6256 N  N   . GLU F 6 27  ? 151.834 153.197 141.831 1.00 68.46  ? 27  GLU A N   1 
ATOM   6257 C  CA  . GLU F 6 27  ? 151.072 152.366 140.906 1.00 67.43  ? 27  GLU A CA  1 
ATOM   6258 C  C   . GLU F 6 27  ? 151.978 151.502 140.039 1.00 68.14  ? 27  GLU A C   1 
ATOM   6259 O  O   . GLU F 6 27  ? 151.651 150.340 139.765 1.00 67.49  ? 27  GLU A O   1 
ATOM   6260 C  CB  . GLU F 6 27  ? 150.189 153.250 140.032 1.00 67.31  ? 27  GLU A CB  1 
ATOM   6261 C  CG  . GLU F 6 27  ? 148.784 152.732 139.842 1.00 74.02  ? 27  GLU A CG  1 
ATOM   6262 C  CD  . GLU F 6 27  ? 147.883 153.091 140.998 1.00 82.83  ? 27  GLU A CD  1 
ATOM   6263 O  OE1 . GLU F 6 27  ? 146.735 152.602 141.038 1.00 88.32  ? 27  GLU A OE1 1 
ATOM   6264 O  OE2 . GLU F 6 27  ? 148.328 153.859 141.873 1.00 78.18  ? 27  GLU A OE2 1 
ATOM   6265 N  N   . LYS F 6 28  ? 153.109 152.054 139.594 1.00 71.80  ? 28  LYS A N   1 
ATOM   6266 C  CA  . LYS F 6 28  ? 154.056 151.271 138.808 1.00 64.92  ? 28  LYS A CA  1 
ATOM   6267 C  C   . LYS F 6 28  ? 154.597 150.097 139.607 1.00 72.03  ? 28  LYS A C   1 
ATOM   6268 O  O   . LYS F 6 28  ? 154.749 148.996 139.071 1.00 78.46  ? 28  LYS A O   1 
ATOM   6269 C  CB  . LYS F 6 28  ? 155.201 152.158 138.325 1.00 66.37  ? 28  LYS A CB  1 
ATOM   6270 N  N   . GLN F 6 29  ? 154.904 150.309 140.890 1.00 75.71  ? 29  GLN A N   1 
ATOM   6271 C  CA  . GLN F 6 29  ? 155.373 149.188 141.702 1.00 66.81  ? 29  GLN A CA  1 
ATOM   6272 C  C   . GLN F 6 29  ? 154.263 148.177 141.978 1.00 65.50  ? 29  GLN A C   1 
ATOM   6273 O  O   . GLN F 6 29  ? 154.523 146.967 142.016 1.00 70.78  ? 29  GLN A O   1 
ATOM   6274 C  CB  . GLN F 6 29  ? 155.966 149.691 143.014 1.00 70.79  ? 29  GLN A CB  1 
ATOM   6275 C  CG  . GLN F 6 29  ? 156.367 148.581 143.964 1.00 74.17  ? 29  GLN A CG  1 
ATOM   6276 C  CD  . GLN F 6 29  ? 157.681 147.932 143.580 1.00 77.91  ? 29  GLN A CD  1 
ATOM   6277 O  OE1 . GLN F 6 29  ? 158.652 148.613 143.256 1.00 80.22  ? 29  GLN A OE1 1 
ATOM   6278 N  NE2 . GLN F 6 29  ? 157.718 146.608 143.614 1.00 75.92  ? 29  GLN A NE2 1 
ATOM   6279 N  N   . LEU F 6 30  ? 153.032 148.646 142.182 1.00 66.08  ? 30  LEU A N   1 
ATOM   6280 C  CA  . LEU F 6 30  ? 151.926 147.733 142.458 1.00 64.60  ? 30  LEU A CA  1 
ATOM   6281 C  C   . LEU F 6 30  ? 151.636 146.831 141.266 1.00 65.42  ? 30  LEU A C   1 
ATOM   6282 O  O   . LEU F 6 30  ? 151.355 145.638 141.438 1.00 72.48  ? 30  LEU A O   1 
ATOM   6283 C  CB  . LEU F 6 30  ? 150.676 148.523 142.838 1.00 61.98  ? 30  LEU A CB  1 
ATOM   6284 C  CG  . LEU F 6 30  ? 150.651 149.177 144.216 1.00 58.55  ? 30  LEU A CG  1 
ATOM   6285 C  CD1 . LEU F 6 30  ? 149.255 149.643 144.538 1.00 64.85  ? 30  LEU A CD1 1 
ATOM   6286 C  CD2 . LEU F 6 30  ? 151.143 148.214 145.265 1.00 63.93  ? 30  LEU A CD2 1 
ATOM   6287 N  N   . GLN F 6 31  ? 151.680 147.382 140.050 1.00 71.55  ? 31  GLN A N   1 
ATOM   6288 C  CA  . GLN F 6 31  ? 151.413 146.558 138.872 1.00 73.62  ? 31  GLN A CA  1 
ATOM   6289 C  C   . GLN F 6 31  ? 152.493 145.504 138.664 1.00 69.06  ? 31  GLN A C   1 
ATOM   6290 O  O   . GLN F 6 31  ? 152.225 144.454 138.073 1.00 70.75  ? 31  GLN A O   1 
ATOM   6291 C  CB  . GLN F 6 31  ? 151.269 147.437 137.629 1.00 70.64  ? 31  GLN A CB  1 
ATOM   6292 C  CG  . GLN F 6 31  ? 152.483 147.449 136.717 1.00 74.59  ? 31  GLN A CG  1 
ATOM   6293 C  CD  . GLN F 6 31  ? 152.395 148.513 135.639 1.00 82.99  ? 31  GLN A CD  1 
ATOM   6294 O  OE1 . GLN F 6 31  ? 151.456 149.310 135.610 1.00 79.84  ? 31  GLN A OE1 1 
ATOM   6295 N  NE2 . GLN F 6 31  ? 153.379 148.534 134.749 1.00 77.16  ? 31  GLN A NE2 1 
ATOM   6296 N  N   . LYS F 6 32  ? 153.711 145.765 139.134 1.00 62.98  ? 32  LYS A N   1 
ATOM   6297 C  CA  . LYS F 6 32  ? 154.780 144.778 139.054 1.00 62.16  ? 32  LYS A CA  1 
ATOM   6298 C  C   . LYS F 6 32  ? 154.667 143.727 140.149 1.00 67.49  ? 32  LYS A C   1 
ATOM   6299 O  O   . LYS F 6 32  ? 155.000 142.560 139.920 1.00 69.03  ? 32  LYS A O   1 
ATOM   6300 C  CB  . LYS F 6 32  ? 156.133 145.485 139.119 1.00 64.87  ? 32  LYS A CB  1 
ATOM   6301 C  CG  . LYS F 6 32  ? 157.275 144.640 139.637 1.00 65.69  ? 32  LYS A CG  1 
ATOM   6302 C  CD  . LYS F 6 32  ? 158.608 145.356 139.490 1.00 67.03  ? 32  LYS A CD  1 
ATOM   6303 C  CE  . LYS F 6 32  ? 158.633 146.258 138.267 1.00 72.36  ? 32  LYS A CE  1 
ATOM   6304 N  NZ  . LYS F 6 32  ? 160.022 146.532 137.811 1.00 70.63  ? 32  LYS A NZ  1 
ATOM   6305 N  N   . ASP F 6 33  ? 154.202 144.116 141.338 1.00 71.91  ? 33  ASP A N   1 
ATOM   6306 C  CA  . ASP F 6 33  ? 153.988 143.153 142.416 1.00 65.44  ? 33  ASP A CA  1 
ATOM   6307 C  C   . ASP F 6 33  ? 152.810 142.227 142.140 1.00 68.12  ? 33  ASP A C   1 
ATOM   6308 O  O   . ASP F 6 33  ? 152.829 141.062 142.558 1.00 71.23  ? 33  ASP A O   1 
ATOM   6309 C  CB  . ASP F 6 33  ? 153.766 143.884 143.738 1.00 68.26  ? 33  ASP A CB  1 
ATOM   6310 C  CG  . ASP F 6 33  ? 155.018 143.958 144.577 1.00 80.77  ? 33  ASP A CG  1 
ATOM   6311 O  OD1 . ASP F 6 33  ? 155.921 143.123 144.374 1.00 85.81  ? 33  ASP A OD1 1 
ATOM   6312 O  OD2 . ASP F 6 33  ? 155.103 144.852 145.445 1.00 76.29  ? 33  ASP A OD2 1 
ATOM   6313 N  N   . LYS F 6 34  ? 151.777 142.726 141.458 1.00 61.19  ? 34  LYS A N   1 
ATOM   6314 C  CA  . LYS F 6 34  ? 150.623 141.894 141.138 1.00 56.77  ? 34  LYS A CA  1 
ATOM   6315 C  C   . LYS F 6 34  ? 151.001 140.728 140.236 1.00 68.44  ? 34  LYS A C   1 
ATOM   6316 O  O   . LYS F 6 34  ? 150.399 139.654 140.326 1.00 66.66  ? 34  LYS A O   1 
ATOM   6317 C  CB  . LYS F 6 34  ? 149.539 142.746 140.482 1.00 60.47  ? 34  LYS A CB  1 
ATOM   6318 C  CG  . LYS F 6 34  ? 148.255 142.017 140.163 1.00 56.90  ? 34  LYS A CG  1 
ATOM   6319 C  CD  . LYS F 6 34  ? 147.236 142.960 139.564 1.00 64.03  ? 34  LYS A CD  1 
ATOM   6320 C  CE  . LYS F 6 34  ? 145.952 142.230 139.219 1.00 70.51  ? 34  LYS A CE  1 
ATOM   6321 N  NZ  . LYS F 6 34  ? 144.934 143.141 138.626 1.00 71.57  ? 34  LYS A NZ  1 
ATOM   6322 N  N   . GLN F 6 35  ? 151.990 140.920 139.363 1.00 73.60  ? 35  GLN A N   1 
ATOM   6323 C  CA  . GLN F 6 35  ? 152.446 139.836 138.499 1.00 64.28  ? 35  GLN A CA  1 
ATOM   6324 C  C   . GLN F 6 35  ? 153.045 138.694 139.308 1.00 62.65  ? 35  GLN A C   1 
ATOM   6325 O  O   . GLN F 6 35  ? 152.782 137.520 139.026 1.00 68.19  ? 35  GLN A O   1 
ATOM   6326 C  CB  . GLN F 6 35  ? 153.461 140.371 137.490 1.00 65.17  ? 35  GLN A CB  1 
ATOM   6327 C  CG  . GLN F 6 35  ? 154.299 139.311 136.786 1.00 73.16  ? 35  GLN A CG  1 
ATOM   6328 C  CD  . GLN F 6 35  ? 153.510 138.478 135.792 1.00 78.85  ? 35  GLN A CD  1 
ATOM   6329 O  OE1 . GLN F 6 35  ? 152.326 138.717 135.552 1.00 78.54  ? 35  GLN A OE1 1 
ATOM   6330 N  NE2 . GLN F 6 35  ? 154.171 137.490 135.203 1.00 75.37  ? 35  GLN A NE2 1 
ATOM   6331 N  N   . VAL F 6 36  ? 153.862 139.014 140.309 1.00 54.61  ? 36  VAL A N   1 
ATOM   6332 C  CA  . VAL F 6 36  ? 154.452 137.975 141.144 1.00 53.42  ? 36  VAL A CA  1 
ATOM   6333 C  C   . VAL F 6 36  ? 153.402 137.330 142.040 1.00 55.44  ? 36  VAL A C   1 
ATOM   6334 O  O   . VAL F 6 36  ? 153.428 136.113 142.251 1.00 57.44  ? 36  VAL A O   1 
ATOM   6335 C  CB  . VAL F 6 36  ? 155.621 138.558 141.954 1.00 60.90  ? 36  VAL A CB  1 
ATOM   6336 C  CG1 . VAL F 6 36  ? 155.810 137.809 143.252 1.00 62.35  ? 36  VAL A CG1 1 
ATOM   6337 C  CG2 . VAL F 6 36  ? 156.895 138.516 141.139 1.00 65.31  ? 36  VAL A CG2 1 
ATOM   6338 N  N   . TYR F 6 37  ? 152.467 138.118 142.576 1.00 60.07  ? 37  TYR A N   1 
ATOM   6339 C  CA  . TYR F 6 37  ? 151.456 137.564 143.471 1.00 53.54  ? 37  TYR A CA  1 
ATOM   6340 C  C   . TYR F 6 37  ? 150.574 136.542 142.764 1.00 55.63  ? 37  TYR A C   1 
ATOM   6341 O  O   . TYR F 6 37  ? 150.250 135.496 143.332 1.00 63.94  ? 37  TYR A O   1 
ATOM   6342 C  CB  . TYR F 6 37  ? 150.604 138.690 144.051 1.00 53.01  ? 37  TYR A CB  1 
ATOM   6343 C  CG  . TYR F 6 37  ? 149.419 138.236 144.873 1.00 52.87  ? 37  TYR A CG  1 
ATOM   6344 C  CD1 . TYR F 6 37  ? 149.559 137.911 146.214 1.00 53.32  ? 37  TYR A CD1 1 
ATOM   6345 C  CD2 . TYR F 6 37  ? 148.156 138.152 144.312 1.00 53.93  ? 37  TYR A CD2 1 
ATOM   6346 C  CE1 . TYR F 6 37  ? 148.478 137.507 146.964 1.00 47.14  ? 37  TYR A CE1 1 
ATOM   6347 C  CE2 . TYR F 6 37  ? 147.073 137.746 145.054 1.00 51.97  ? 37  TYR A CE2 1 
ATOM   6348 C  CZ  . TYR F 6 37  ? 147.240 137.427 146.377 1.00 52.12  ? 37  TYR A CZ  1 
ATOM   6349 O  OH  . TYR F 6 37  ? 146.154 137.024 147.114 1.00 62.91  ? 37  TYR A OH  1 
ATOM   6350 N  N   . ARG F 6 38  ? 150.175 136.825 141.525 1.00 58.88  ? 38  ARG A N   1 
ATOM   6351 C  CA  . ARG F 6 38  ? 149.214 135.976 140.830 1.00 57.02  ? 38  ARG A CA  1 
ATOM   6352 C  C   . ARG F 6 38  ? 149.829 134.708 140.254 1.00 60.76  ? 38  ARG A C   1 
ATOM   6353 O  O   . ARG F 6 38  ? 149.097 133.754 139.978 1.00 66.10  ? 38  ARG A O   1 
ATOM   6354 C  CB  . ARG F 6 38  ? 148.535 136.765 139.714 1.00 55.32  ? 38  ARG A CB  1 
ATOM   6355 C  CG  . ARG F 6 38  ? 147.380 137.620 140.193 1.00 63.35  ? 38  ARG A CG  1 
ATOM   6356 C  CD  . ARG F 6 38  ? 146.285 137.704 139.153 1.00 66.06  ? 38  ARG A CD  1 
ATOM   6357 N  NE  . ARG F 6 38  ? 146.617 138.654 138.099 1.00 78.46  ? 38  ARG A NE  1 
ATOM   6358 C  CZ  . ARG F 6 38  ? 145.723 139.290 137.356 1.00 77.22  ? 38  ARG A CZ  1 
ATOM   6359 N  NH1 . ARG F 6 38  ? 144.427 139.088 137.511 1.00 74.13  ? 38  ARG A NH1 1 
ATOM   6360 N  NH2 . ARG F 6 38  ? 146.143 140.151 136.434 1.00 66.84  ? 38  ARG A NH2 1 
ATOM   6361 N  N   . ALA F 6 39  ? 151.145 134.665 140.077 1.00 55.75  ? 39  ALA A N   1 
ATOM   6362 C  CA  . ALA F 6 39  ? 151.818 133.516 139.493 1.00 51.66  ? 39  ALA A CA  1 
ATOM   6363 C  C   . ALA F 6 39  ? 152.351 132.549 140.541 1.00 61.64  ? 39  ALA A C   1 
ATOM   6364 O  O   . ALA F 6 39  ? 153.154 131.674 140.210 1.00 62.84  ? 39  ALA A O   1 
ATOM   6365 C  CB  . ALA F 6 39  ? 152.954 133.984 138.588 1.00 50.01  ? 39  ALA A CB  1 
ATOM   6366 N  N   . THR F 6 40  ? 151.928 132.692 141.793 1.00 61.58  ? 40  THR A N   1 
ATOM   6367 C  CA  . THR F 6 40  ? 152.385 131.863 142.895 1.00 56.62  ? 40  THR A CA  1 
ATOM   6368 C  C   . THR F 6 40  ? 151.191 131.164 143.528 1.00 54.48  ? 40  THR A C   1 
ATOM   6369 O  O   . THR F 6 40  ? 150.096 131.725 143.603 1.00 51.98  ? 40  THR A O   1 
ATOM   6370 C  CB  . THR F 6 40  ? 153.127 132.705 143.941 1.00 59.95  ? 40  THR A CB  1 
ATOM   6371 O  OG1 . THR F 6 40  ? 154.142 133.477 143.292 1.00 66.59  ? 40  THR A OG1 1 
ATOM   6372 C  CG2 . THR F 6 40  ? 153.778 131.828 144.988 1.00 62.98  ? 40  THR A CG2 1 
ATOM   6373 N  N   . HIS F 6 41  ? 151.405 129.930 143.973 1.00 55.11  ? 41  HIS A N   1 
ATOM   6374 C  CA  . HIS F 6 41  ? 150.351 129.101 144.540 1.00 52.48  ? 41  HIS A CA  1 
ATOM   6375 C  C   . HIS F 6 41  ? 150.612 128.887 146.021 1.00 50.69  ? 41  HIS A C   1 
ATOM   6376 O  O   . HIS F 6 41  ? 151.664 128.368 146.400 1.00 62.65  ? 41  HIS A O   1 
ATOM   6377 C  CB  . HIS F 6 41  ? 150.264 127.759 143.809 1.00 48.83  ? 41  HIS A CB  1 
ATOM   6378 C  CG  . HIS F 6 41  ? 150.023 127.892 142.339 1.00 54.09  ? 41  HIS A CG  1 
ATOM   6379 N  ND1 . HIS F 6 41  ? 151.042 127.881 141.414 1.00 55.67  ? 41  HIS A ND1 1 
ATOM   6380 C  CD2 . HIS F 6 41  ? 148.879 128.057 141.634 1.00 52.83  ? 41  HIS A CD2 1 
ATOM   6381 C  CE1 . HIS F 6 41  ? 150.536 128.026 140.203 1.00 58.16  ? 41  HIS A CE1 1 
ATOM   6382 N  NE2 . HIS F 6 41  ? 149.226 128.135 140.309 1.00 54.56  ? 41  HIS A NE2 1 
ATOM   6383 N  N   . ARG F 6 42  ? 149.648 129.272 146.850 1.00 39.82  ? 42  ARG A N   1 
ATOM   6384 C  CA  . ARG F 6 42  ? 149.780 129.221 148.297 1.00 45.95  ? 42  ARG A CA  1 
ATOM   6385 C  C   . ARG F 6 42  ? 149.048 128.009 148.852 1.00 50.39  ? 42  ARG A C   1 
ATOM   6386 O  O   . ARG F 6 42  ? 147.905 127.743 148.481 1.00 59.52  ? 42  ARG A O   1 
ATOM   6387 C  CB  . ARG F 6 42  ? 149.228 130.495 148.935 1.00 49.94  ? 42  ARG A CB  1 
ATOM   6388 C  CG  . ARG F 6 42  ? 149.979 131.753 148.565 1.00 46.94  ? 42  ARG A CG  1 
ATOM   6389 C  CD  . ARG F 6 42  ? 149.080 132.968 148.657 1.00 46.32  ? 42  ARG A CD  1 
ATOM   6390 N  NE  . ARG F 6 42  ? 148.256 133.125 147.466 1.00 54.60  ? 42  ARG A NE  1 
ATOM   6391 C  CZ  . ARG F 6 42  ? 148.689 133.618 146.314 1.00 60.44  ? 42  ARG A CZ  1 
ATOM   6392 N  NH1 . ARG F 6 42  ? 149.933 134.043 146.169 1.00 58.37  ? 42  ARG A NH1 1 
ATOM   6393 N  NH2 . ARG F 6 42  ? 147.855 133.681 145.282 1.00 49.74  ? 42  ARG A NH2 1 
ATOM   6394 N  N   . LEU F 6 43  ? 149.703 127.286 149.757 1.00 40.88  ? 43  LEU A N   1 
ATOM   6395 C  CA  . LEU F 6 43  ? 149.169 126.049 150.314 1.00 39.08  ? 43  LEU A CA  1 
ATOM   6396 C  C   . LEU F 6 43  ? 149.192 126.130 151.831 1.00 46.96  ? 43  LEU A C   1 
ATOM   6397 O  O   . LEU F 6 43  ? 150.103 126.728 152.407 1.00 56.70  ? 43  LEU A O   1 
ATOM   6398 C  CB  . LEU F 6 43  ? 149.982 124.843 149.842 1.00 49.45  ? 43  LEU A CB  1 
ATOM   6399 C  CG  . LEU F 6 43  ? 150.093 124.627 148.339 1.00 46.79  ? 43  LEU A CG  1 
ATOM   6400 C  CD1 . LEU F 6 43  ? 151.327 123.813 148.027 1.00 48.62  ? 43  LEU A CD1 1 
ATOM   6401 C  CD2 . LEU F 6 43  ? 148.859 123.933 147.839 1.00 46.88  ? 43  LEU A CD2 1 
ATOM   6402 N  N   . LEU F 6 44  ? 148.199 125.524 152.474 1.00 32.28  ? 44  LEU A N   1 
ATOM   6403 C  CA  . LEU F 6 44  ? 148.154 125.419 153.924 1.00 26.00  ? 44  LEU A CA  1 
ATOM   6404 C  C   . LEU F 6 44  ? 148.408 123.976 154.336 1.00 34.52  ? 44  LEU A C   1 
ATOM   6405 O  O   . LEU F 6 44  ? 147.947 123.044 153.679 1.00 64.63  ? 44  LEU A O   1 
ATOM   6406 C  CB  . LEU F 6 44  ? 146.802 125.896 154.460 1.00 34.06  ? 44  LEU A CB  1 
ATOM   6407 C  CG  . LEU F 6 44  ? 146.528 125.774 155.961 1.00 42.09  ? 44  LEU A CG  1 
ATOM   6408 C  CD1 . LEU F 6 44  ? 147.505 126.598 156.771 1.00 43.27  ? 44  LEU A CD1 1 
ATOM   6409 C  CD2 . LEU F 6 44  ? 145.103 126.168 156.284 1.00 31.57  ? 44  LEU A CD2 1 
ATOM   6410 N  N   . LEU F 6 45  ? 149.138 123.796 155.431 1.00 38.97  ? 45  LEU A N   1 
ATOM   6411 C  CA  . LEU F 6 45  ? 149.601 122.488 155.884 1.00 38.15  ? 45  LEU A CA  1 
ATOM   6412 C  C   . LEU F 6 45  ? 149.164 122.238 157.320 1.00 49.17  ? 45  LEU A C   1 
ATOM   6413 O  O   . LEU F 6 45  ? 149.972 121.975 158.210 1.00 68.46  ? 45  LEU A O   1 
ATOM   6414 C  CB  . LEU F 6 45  ? 151.116 122.355 155.741 1.00 41.06  ? 45  LEU A CB  1 
ATOM   6415 C  CG  . LEU F 6 45  ? 151.770 121.013 156.101 1.00 45.99  ? 45  LEU A CG  1 
ATOM   6416 C  CD1 . LEU F 6 45  ? 151.377 119.918 155.145 1.00 56.18  ? 45  LEU A CD1 1 
ATOM   6417 C  CD2 . LEU F 6 45  ? 153.273 121.145 156.167 1.00 55.08  ? 45  LEU A CD2 1 
ATOM   6418 N  N   . LEU F 6 46  ? 147.873 122.376 157.592 1.00 49.34  ? 46  LEU A N   1 
ATOM   6419 C  CA  . LEU F 6 46  ? 147.385 122.086 158.932 1.00 62.27  ? 46  LEU A CA  1 
ATOM   6420 C  C   . LEU F 6 46  ? 147.287 120.571 159.117 1.00 48.13  ? 46  LEU A C   1 
ATOM   6421 O  O   . LEU F 6 46  ? 147.606 119.786 158.224 1.00 41.87  ? 46  LEU A O   1 
ATOM   6422 C  CB  . LEU F 6 46  ? 146.063 122.805 159.195 1.00 63.15  ? 46  LEU A CB  1 
ATOM   6423 C  CG  . LEU F 6 46  ? 144.824 122.508 158.361 1.00 53.06  ? 46  LEU A CG  1 
ATOM   6424 C  CD1 . LEU F 6 46  ? 144.185 121.242 158.864 1.00 57.53  ? 46  LEU A CD1 1 
ATOM   6425 C  CD2 . LEU F 6 46  ? 143.858 123.641 158.444 1.00 51.33  ? 46  LEU A CD2 1 
ATOM   6426 N  N   . GLY F 6 47  ? 146.840 120.147 160.293 1.00 59.16  ? 47  GLY A N   1 
ATOM   6427 C  CA  . GLY F 6 47  ? 146.826 118.744 160.642 1.00 60.26  ? 47  GLY A CA  1 
ATOM   6428 C  C   . GLY F 6 47  ? 148.079 118.317 161.372 1.00 61.55  ? 47  GLY A C   1 
ATOM   6429 O  O   . GLY F 6 47  ? 148.036 118.034 162.573 1.00 65.22  ? 47  GLY A O   1 
ATOM   6430 N  N   . ALA F 6 48  ? 149.202 118.269 160.662 1.00 59.88  ? 48  ALA A N   1 
ATOM   6431 C  CA  . ALA F 6 48  ? 150.464 117.823 161.238 1.00 71.50  ? 48  ALA A CA  1 
ATOM   6432 C  C   . ALA F 6 48  ? 151.586 118.128 160.258 1.00 73.40  ? 48  ALA A C   1 
ATOM   6433 O  O   . ALA F 6 48  ? 151.406 118.866 159.287 1.00 72.55  ? 48  ALA A O   1 
ATOM   6434 C  CB  . ALA F 6 48  ? 150.440 116.328 161.579 1.00 67.92  ? 48  ALA A CB  1 
ATOM   6435 N  N   . GLY F 6 49  ? 152.753 117.563 160.540 1.00 79.15  ? 49  GLY A N   1 
ATOM   6436 C  CA  . GLY F 6 49  ? 153.884 117.654 159.640 1.00 77.69  ? 49  GLY A CA  1 
ATOM   6437 C  C   . GLY F 6 49  ? 154.367 116.278 159.239 1.00 78.66  ? 49  GLY A C   1 
ATOM   6438 O  O   . GLY F 6 49  ? 153.923 115.275 159.797 1.00 77.17  ? 49  GLY A O   1 
ATOM   6439 N  N   . PHE F 6 194 ? 155.147 129.961 160.156 1.00 72.36  ? 208 PHE A N   1 
ATOM   6440 C  CA  . PHE F 6 194 ? 156.219 129.369 159.406 1.00 65.71  ? 208 PHE A CA  1 
ATOM   6441 C  C   . PHE F 6 194 ? 155.951 129.226 157.922 1.00 60.06  ? 208 PHE A C   1 
ATOM   6442 O  O   . PHE F 6 194 ? 154.936 128.745 157.575 1.00 59.01  ? 208 PHE A O   1 
ATOM   6443 C  CB  . PHE F 6 194 ? 156.472 128.063 160.040 1.00 49.54  ? 208 PHE A CB  1 
ATOM   6444 C  CG  . PHE F 6 194 ? 156.775 128.157 161.497 1.00 59.10  ? 208 PHE A CG  1 
ATOM   6445 C  CD1 . PHE F 6 194 ? 157.825 128.923 161.948 1.00 58.87  ? 208 PHE A CD1 1 
ATOM   6446 C  CD2 . PHE F 6 194 ? 156.013 127.485 162.418 1.00 57.90  ? 208 PHE A CD2 1 
ATOM   6447 C  CE1 . PHE F 6 194 ? 158.108 129.021 163.289 1.00 55.76  ? 208 PHE A CE1 1 
ATOM   6448 C  CE2 . PHE F 6 194 ? 156.288 127.573 163.761 1.00 54.56  ? 208 PHE A CE2 1 
ATOM   6449 C  CZ  . PHE F 6 194 ? 157.337 128.343 164.198 1.00 64.78  ? 208 PHE A CZ  1 
ATOM   6450 N  N   . GLU F 6 195 ? 156.851 129.672 157.049 1.00 63.90  ? 209 GLU A N   1 
ATOM   6451 C  CA  . GLU F 6 195 ? 156.712 129.579 155.599 1.00 61.66  ? 209 GLU A CA  1 
ATOM   6452 C  C   . GLU F 6 195 ? 157.808 128.819 154.949 1.00 65.28  ? 209 GLU A C   1 
ATOM   6453 O  O   . GLU F 6 195 ? 158.808 128.574 155.561 1.00 72.19  ? 209 GLU A O   1 
ATOM   6454 C  CB  . GLU F 6 195 ? 156.780 130.912 154.969 1.00 59.07  ? 209 GLU A CB  1 
ATOM   6455 N  N   . THR F 6 196 ? 157.632 128.429 153.705 1.00 67.23  ? 210 THR A N   1 
ATOM   6456 C  CA  . THR F 6 196 ? 158.607 127.659 152.955 1.00 65.82  ? 210 THR A CA  1 
ATOM   6457 C  C   . THR F 6 196 ? 158.294 127.906 151.523 1.00 68.49  ? 210 THR A C   1 
ATOM   6458 O  O   . THR F 6 196 ? 157.185 127.724 151.103 1.00 68.32  ? 210 THR A O   1 
ATOM   6459 C  CB  . THR F 6 196 ? 158.572 126.161 153.205 1.00 57.89  ? 210 THR A CB  1 
ATOM   6460 N  N   . LYS F 6 197 ? 159.264 128.374 150.770 1.00 72.96  ? 211 LYS A N   1 
ATOM   6461 C  CA  . LYS F 6 197 ? 159.122 128.644 149.388 1.00 67.25  ? 211 LYS A CA  1 
ATOM   6462 C  C   . LYS F 6 197 ? 159.897 127.595 148.605 1.00 75.79  ? 211 LYS A C   1 
ATOM   6463 O  O   . LYS F 6 197 ? 161.097 127.568 148.696 1.00 80.74  ? 211 LYS A O   1 
ATOM   6464 C  CB  . LYS F 6 197 ? 159.710 129.994 149.162 1.00 59.74  ? 211 LYS A CB  1 
ATOM   6465 C  CG  . LYS F 6 197 ? 158.935 131.113 149.814 1.00 68.04  ? 211 LYS A CG  1 
ATOM   6466 C  CD  . LYS F 6 197 ? 159.608 132.447 149.558 1.00 74.17  ? 211 LYS A CD  1 
ATOM   6467 C  CE  . LYS F 6 197 ? 158.819 133.580 150.192 1.00 75.92  ? 211 LYS A CE  1 
ATOM   6468 N  NZ  . LYS F 6 197 ? 159.458 134.908 149.985 1.00 71.36  ? 211 LYS A NZ  1 
ATOM   6469 N  N   . PHE F 6 198 ? 159.230 126.722 147.852 1.00 72.83  ? 212 PHE A N   1 
ATOM   6470 C  CA  . PHE F 6 198 ? 159.860 125.694 147.036 1.00 67.32  ? 212 PHE A CA  1 
ATOM   6471 C  C   . PHE F 6 198 ? 159.284 125.775 145.631 1.00 71.52  ? 212 PHE A C   1 
ATOM   6472 O  O   . PHE F 6 198 ? 158.155 126.222 145.426 1.00 76.95  ? 212 PHE A O   1 
ATOM   6473 C  CB  . PHE F 6 198 ? 159.674 124.299 147.639 1.00 63.63  ? 212 PHE A CB  1 
ATOM   6474 C  CG  . PHE F 6 198 ? 158.262 123.792 147.595 1.00 64.20  ? 212 PHE A CG  1 
ATOM   6475 C  CD1 . PHE F 6 198 ? 157.347 124.169 148.555 1.00 71.10  ? 212 PHE A CD1 1 
ATOM   6476 C  CD2 . PHE F 6 198 ? 157.859 122.916 146.607 1.00 72.34  ? 212 PHE A CD2 1 
ATOM   6477 C  CE1 . PHE F 6 198 ? 156.053 123.695 148.522 1.00 73.74  ? 212 PHE A CE1 1 
ATOM   6478 C  CE2 . PHE F 6 198 ? 156.563 122.441 146.568 1.00 72.90  ? 212 PHE A CE2 1 
ATOM   6479 C  CZ  . PHE F 6 198 ? 155.661 122.828 147.529 1.00 71.06  ? 212 PHE A CZ  1 
ATOM   6480 N  N   . GLN F 6 199 ? 160.084 125.342 144.661 1.00 77.03  ? 213 GLN A N   1 
ATOM   6481 C  CA  . GLN F 6 199 ? 159.737 125.485 143.254 1.00 72.74  ? 213 GLN A CA  1 
ATOM   6482 C  C   . GLN F 6 199 ? 159.923 124.147 142.558 1.00 72.92  ? 213 GLN A C   1 
ATOM   6483 O  O   . GLN F 6 199 ? 160.963 123.505 142.719 1.00 77.20  ? 213 GLN A O   1 
ATOM   6484 C  CB  . GLN F 6 199 ? 160.606 126.561 142.596 1.00 71.99  ? 213 GLN A CB  1 
ATOM   6485 C  CG  . GLN F 6 199 ? 160.482 126.644 141.096 1.00 73.70  ? 213 GLN A CG  1 
ATOM   6486 C  CD  . GLN F 6 199 ? 161.463 127.624 140.492 1.00 79.75  ? 213 GLN A CD  1 
ATOM   6487 O  OE1 . GLN F 6 199 ? 162.191 127.296 139.558 1.00 79.42  ? 213 GLN A OE1 1 
ATOM   6488 N  NE2 . GLN F 6 199 ? 161.484 128.840 141.020 1.00 76.95  ? 213 GLN A NE2 1 
ATOM   6489 N  N   . VAL F 6 200 ? 158.917 123.730 141.796 1.00 72.48  ? 214 VAL A N   1 
ATOM   6490 C  CA  . VAL F 6 200 ? 158.941 122.457 141.088 1.00 75.84  ? 214 VAL A CA  1 
ATOM   6491 C  C   . VAL F 6 200 ? 158.559 122.698 139.636 1.00 74.94  ? 214 VAL A C   1 
ATOM   6492 O  O   . VAL F 6 200 ? 157.446 123.151 139.354 1.00 76.70  ? 214 VAL A O   1 
ATOM   6493 C  CB  . VAL F 6 200 ? 157.993 121.429 141.731 1.00 72.83  ? 214 VAL A CB  1 
ATOM   6494 C  CG1 . VAL F 6 200 ? 157.760 120.267 140.797 1.00 69.94  ? 214 VAL A CG1 1 
ATOM   6495 C  CG2 . VAL F 6 200 ? 158.568 120.941 143.036 1.00 77.94  ? 214 VAL A CG2 1 
ATOM   6496 N  N   . ASP F 6 201 ? 159.476 122.383 138.720 1.00 73.87  ? 215 ASP A N   1 
ATOM   6497 C  CA  . ASP F 6 201 ? 159.251 122.530 137.281 1.00 76.89  ? 215 ASP A CA  1 
ATOM   6498 C  C   . ASP F 6 201 ? 158.921 123.973 136.904 1.00 79.43  ? 215 ASP A C   1 
ATOM   6499 O  O   . ASP F 6 201 ? 158.006 124.239 136.123 1.00 78.50  ? 215 ASP A O   1 
ATOM   6500 C  CB  . ASP F 6 201 ? 158.157 121.578 136.797 1.00 79.39  ? 215 ASP A CB  1 
ATOM   6501 C  CG  . ASP F 6 201 ? 158.670 120.171 136.564 1.00 85.44  ? 215 ASP A CG  1 
ATOM   6502 O  OD1 . ASP F 6 201 ? 159.894 120.002 136.385 1.00 88.11  ? 215 ASP A OD1 1 
ATOM   6503 O  OD2 . ASP F 6 201 ? 157.849 119.231 136.561 1.00 82.06  ? 215 ASP A OD2 1 
ATOM   6504 N  N   . LYS F 6 202 ? 159.677 124.912 137.472 1.00 77.14  ? 216 LYS A N   1 
ATOM   6505 C  CA  . LYS F 6 202 ? 159.640 126.332 137.131 1.00 73.43  ? 216 LYS A CA  1 
ATOM   6506 C  C   . LYS F 6 202 ? 158.354 127.034 137.554 1.00 72.31  ? 216 LYS A C   1 
ATOM   6507 O  O   . LYS F 6 202 ? 158.044 128.111 137.038 1.00 74.46  ? 216 LYS A O   1 
ATOM   6508 C  CB  . LYS F 6 202 ? 159.875 126.554 135.633 1.00 76.77  ? 216 LYS A CB  1 
ATOM   6509 C  CG  . LYS F 6 202 ? 161.336 126.511 135.218 1.00 80.04  ? 216 LYS A CG  1 
ATOM   6510 C  CD  . LYS F 6 202 ? 161.474 126.427 133.708 1.00 79.87  ? 216 LYS A CD  1 
ATOM   6511 C  CE  . LYS F 6 202 ? 162.471 125.353 133.306 1.00 79.88  ? 216 LYS A CE  1 
ATOM   6512 N  NZ  . LYS F 6 202 ? 162.271 124.092 134.072 1.00 75.83  ? 216 LYS A NZ  1 
ATOM   6513 N  N   . VAL F 6 203 ? 157.592 126.468 138.485 1.00 67.92  ? 217 VAL A N   1 
ATOM   6514 C  CA  . VAL F 6 203 ? 156.443 127.144 139.075 1.00 70.14  ? 217 VAL A CA  1 
ATOM   6515 C  C   . VAL F 6 203 ? 156.614 127.144 140.587 1.00 71.97  ? 217 VAL A C   1 
ATOM   6516 O  O   . VAL F 6 203 ? 156.955 126.117 141.181 1.00 73.51  ? 217 VAL A O   1 
ATOM   6517 C  CB  . VAL F 6 203 ? 155.102 126.501 138.654 1.00 63.73  ? 217 VAL A CB  1 
ATOM   6518 C  CG1 . VAL F 6 203 ? 153.947 127.140 139.369 1.00 57.46  ? 217 VAL A CG1 1 
ATOM   6519 C  CG2 . VAL F 6 203 ? 154.906 126.576 137.155 1.00 66.06  ? 217 VAL A CG2 1 
ATOM   6520 N  N   . ASN F 6 204 ? 156.400 128.308 141.202 1.00 67.37  ? 218 ASN A N   1 
ATOM   6521 C  CA  . ASN F 6 204 ? 156.704 128.518 142.610 1.00 59.98  ? 218 ASN A CA  1 
ATOM   6522 C  C   . ASN F 6 204 ? 155.508 128.193 143.492 1.00 60.26  ? 218 ASN A C   1 
ATOM   6523 O  O   . ASN F 6 204 ? 154.370 128.543 143.172 1.00 60.96  ? 218 ASN A O   1 
ATOM   6524 C  CB  . ASN F 6 204 ? 157.139 129.962 142.857 1.00 65.45  ? 218 ASN A CB  1 
ATOM   6525 C  CG  . ASN F 6 204 ? 158.044 130.494 141.772 1.00 68.97  ? 218 ASN A CG  1 
ATOM   6526 O  OD1 . ASN F 6 204 ? 159.253 130.283 141.801 1.00 65.89  ? 218 ASN A OD1 1 
ATOM   6527 N  ND2 . ASN F 6 204 ? 157.464 131.196 140.811 1.00 67.64  ? 218 ASN A ND2 1 
ATOM   6528 N  N   . PHE F 6 205 ? 155.782 127.536 144.616 1.00 60.71  ? 219 PHE A N   1 
ATOM   6529 C  CA  . PHE F 6 205 ? 154.778 127.186 145.607 1.00 59.52  ? 219 PHE A CA  1 
ATOM   6530 C  C   . PHE F 6 205 ? 155.146 127.824 146.939 1.00 59.09  ? 219 PHE A C   1 
ATOM   6531 O  O   . PHE F 6 205 ? 156.322 128.010 147.255 1.00 68.72  ? 219 PHE A O   1 
ATOM   6532 C  CB  . PHE F 6 205 ? 154.657 125.668 145.774 1.00 56.34  ? 219 PHE A CB  1 
ATOM   6533 C  CG  . PHE F 6 205 ? 153.942 124.985 144.645 1.00 56.84  ? 219 PHE A CG  1 
ATOM   6534 C  CD1 . PHE F 6 205 ? 152.566 124.992 144.575 1.00 57.29  ? 219 PHE A CD1 1 
ATOM   6535 C  CD2 . PHE F 6 205 ? 154.649 124.325 143.661 1.00 56.51  ? 219 PHE A CD2 1 
ATOM   6536 C  CE1 . PHE F 6 205 ? 151.913 124.363 143.547 1.00 58.85  ? 219 PHE A CE1 1 
ATOM   6537 C  CE2 . PHE F 6 205 ? 153.996 123.696 142.630 1.00 55.57  ? 219 PHE A CE2 1 
ATOM   6538 C  CZ  . PHE F 6 205 ? 152.627 123.716 142.574 1.00 56.36  ? 219 PHE A CZ  1 
ATOM   6539 N  N   . HIS F 6 206 ? 154.125 128.155 147.725 1.00 57.64  ? 220 HIS A N   1 
ATOM   6540 C  CA  . HIS F 6 206 ? 154.312 128.847 148.997 1.00 58.09  ? 220 HIS A CA  1 
ATOM   6541 C  C   . HIS F 6 206 ? 153.496 128.141 150.067 1.00 59.70  ? 220 HIS A C   1 
ATOM   6542 O  O   . HIS F 6 206 ? 152.269 128.259 150.084 1.00 60.10  ? 220 HIS A O   1 
ATOM   6543 C  CB  . HIS F 6 206 ? 153.893 130.311 148.876 1.00 59.54  ? 220 HIS A CB  1 
ATOM   6544 C  CG  . HIS F 6 206 ? 154.499 131.206 149.909 1.00 67.38  ? 220 HIS A CG  1 
ATOM   6545 N  ND1 . HIS F 6 206 ? 154.201 132.548 149.994 1.00 65.89  ? 220 HIS A ND1 1 
ATOM   6546 C  CD2 . HIS F 6 206 ? 155.382 130.952 150.902 1.00 68.98  ? 220 HIS A CD2 1 
ATOM   6547 C  CE1 . HIS F 6 206 ? 154.874 133.083 150.995 1.00 65.63  ? 220 HIS A CE1 1 
ATOM   6548 N  NE2 . HIS F 6 206 ? 155.600 132.136 151.562 1.00 67.64  ? 220 HIS A NE2 1 
ATOM   6549 N  N   . MET F 6 207 ? 154.168 127.424 150.964 1.00 53.15  ? 221 MET A N   1 
ATOM   6550 C  CA  . MET F 6 207 ? 153.511 126.575 151.948 1.00 51.82  ? 221 MET A CA  1 
ATOM   6551 C  C   . MET F 6 207 ? 153.627 127.180 153.339 1.00 55.74  ? 221 MET A C   1 
ATOM   6552 O  O   . MET F 6 207 ? 154.705 127.617 153.744 1.00 65.66  ? 221 MET A O   1 
ATOM   6553 C  CB  . MET F 6 207 ? 154.115 125.174 151.944 1.00 59.84  ? 221 MET A CB  1 
ATOM   6554 C  CG  . MET F 6 207 ? 153.422 124.203 152.877 1.00 59.10  ? 221 MET A CG  1 
ATOM   6555 S  SD  . MET F 6 207 ? 153.204 122.575 152.153 1.00 81.63  ? 221 MET A SD  1 
ATOM   6556 C  CE  . MET F 6 207 ? 154.690 121.768 152.728 1.00 56.94  ? 221 MET A CE  1 
ATOM   6557 N  N   . PHE F 6 208 ? 152.515 127.193 154.073 1.00 47.07  ? 222 PHE A N   1 
ATOM   6558 C  CA  . PHE F 6 208 ? 152.452 127.766 155.411 1.00 45.10  ? 222 PHE A CA  1 
ATOM   6559 C  C   . PHE F 6 208 ? 152.097 126.694 156.427 1.00 47.35  ? 222 PHE A C   1 
ATOM   6560 O  O   . PHE F 6 208 ? 151.274 125.820 156.150 1.00 70.98  ? 222 PHE A O   1 
ATOM   6561 C  CB  . PHE F 6 208 ? 151.423 128.892 155.493 1.00 52.37  ? 222 PHE A CB  1 
ATOM   6562 C  CG  . PHE F 6 208 ? 151.515 129.881 154.379 1.00 61.14  ? 222 PHE A CG  1 
ATOM   6563 C  CD1 . PHE F 6 208 ? 152.515 130.832 154.365 1.00 57.29  ? 222 PHE A CD1 1 
ATOM   6564 C  CD2 . PHE F 6 208 ? 150.589 129.875 153.356 1.00 54.62  ? 222 PHE A CD2 1 
ATOM   6565 C  CE1 . PHE F 6 208 ? 152.598 131.746 153.347 1.00 52.97  ? 222 PHE A CE1 1 
ATOM   6566 C  CE2 . PHE F 6 208 ? 150.668 130.787 152.336 1.00 52.27  ? 222 PHE A CE2 1 
ATOM   6567 C  CZ  . PHE F 6 208 ? 151.673 131.724 152.331 1.00 57.77  ? 222 PHE A CZ  1 
ATOM   6568 N  N   . ASP F 6 209 ? 152.706 126.775 157.603 1.00 50.72  ? 223 ASP A N   1 
ATOM   6569 C  CA  . ASP F 6 209 ? 152.386 125.918 158.735 1.00 50.43  ? 223 ASP A CA  1 
ATOM   6570 C  C   . ASP F 6 209 ? 152.152 126.802 159.950 1.00 60.52  ? 223 ASP A C   1 
ATOM   6571 O  O   . ASP F 6 209 ? 152.924 127.724 160.204 1.00 70.07  ? 223 ASP A O   1 
ATOM   6572 C  CB  . ASP F 6 209 ? 153.512 124.925 159.003 1.00 48.99  ? 223 ASP A CB  1 
ATOM   6573 C  CG  . ASP F 6 209 ? 153.050 123.735 159.799 1.00 68.37  ? 223 ASP A CG  1 
ATOM   6574 O  OD1 . ASP F 6 209 ? 151.825 123.530 159.896 1.00 74.07  ? 223 ASP A OD1 1 
ATOM   6575 O  OD2 . ASP F 6 209 ? 153.912 123.002 160.326 1.00 74.64  ? 223 ASP A OD2 1 
ATOM   6576 N  N   . VAL F 6 210 ? 151.105 126.511 160.711 1.00 60.63  ? 224 VAL A N   1 
ATOM   6577 C  CA  . VAL F 6 210 ? 150.551 127.482 161.647 1.00 57.45  ? 224 VAL A CA  1 
ATOM   6578 C  C   . VAL F 6 210 ? 150.713 126.946 163.068 1.00 57.86  ? 224 VAL A C   1 
ATOM   6579 O  O   . VAL F 6 210 ? 149.820 127.070 163.913 1.00 58.09  ? 224 VAL A O   1 
ATOM   6580 C  CB  . VAL F 6 210 ? 149.087 127.791 161.270 1.00 60.01  ? 224 VAL A CB  1 
ATOM   6581 C  CG1 . VAL F 6 210 ? 148.141 126.745 161.829 1.00 58.88  ? 224 VAL A CG1 1 
ATOM   6582 C  CG2 . VAL F 6 210 ? 148.683 129.250 161.573 1.00 58.66  ? 224 VAL A CG2 1 
ATOM   6583 N  N   . GLY F 6 211 ? 151.839 126.297 163.326 1.00 54.10  ? 225 GLY A N   1 
ATOM   6584 C  CA  . GLY F 6 211 ? 152.054 125.612 164.586 1.00 65.76  ? 225 GLY A CA  1 
ATOM   6585 C  C   . GLY F 6 211 ? 152.186 126.453 165.842 1.00 64.72  ? 225 GLY A C   1 
ATOM   6586 O  O   . GLY F 6 211 ? 152.179 125.883 166.936 1.00 61.59  ? 225 GLY A O   1 
ATOM   6587 N  N   . GLY F 6 212 ? 152.302 127.772 165.746 1.00 46.22  ? 226 GLY A N   1 
ATOM   6588 C  CA  . GLY F 6 212 ? 152.555 128.571 166.929 1.00 50.48  ? 226 GLY A CA  1 
ATOM   6589 C  C   . GLY F 6 212 ? 151.354 129.114 167.672 1.00 52.21  ? 226 GLY A C   1 
ATOM   6590 O  O   . GLY F 6 212 ? 151.525 129.938 168.575 1.00 40.75  ? 226 GLY A O   1 
ATOM   6591 N  N   . GLN F 6 213 ? 150.143 128.681 167.334 1.00 54.78  ? 227 GLN A N   1 
ATOM   6592 C  CA  . GLN F 6 213 ? 148.915 129.252 167.861 1.00 51.25  ? 227 GLN A CA  1 
ATOM   6593 C  C   . GLN F 6 213 ? 148.326 128.365 168.957 1.00 59.13  ? 227 GLN A C   1 
ATOM   6594 O  O   . GLN F 6 213 ? 148.946 127.404 169.417 1.00 59.73  ? 227 GLN A O   1 
ATOM   6595 C  CB  . GLN F 6 213 ? 147.916 129.462 166.726 1.00 53.40  ? 227 GLN A CB  1 
ATOM   6596 C  CG  . GLN F 6 213 ? 148.453 130.268 165.571 1.00 54.16  ? 227 GLN A CG  1 
ATOM   6597 C  CD  . GLN F 6 213 ? 148.557 131.729 165.898 1.00 55.11  ? 227 GLN A CD  1 
ATOM   6598 O  OE1 . GLN F 6 213 ? 147.908 132.214 166.818 1.00 60.07  ? 227 GLN A OE1 1 
ATOM   6599 N  NE2 . GLN F 6 213 ? 149.383 132.444 165.154 1.00 51.08  ? 227 GLN A NE2 1 
ATOM   6600 N  N   . ARG F 6 214 ? 147.111 128.697 169.387 1.00 63.99  ? 228 ARG A N   1 
ATOM   6601 C  CA  . ARG F 6 214 ? 146.385 127.937 170.391 1.00 57.35  ? 228 ARG A CA  1 
ATOM   6602 C  C   . ARG F 6 214 ? 145.470 126.913 169.720 1.00 60.48  ? 228 ARG A C   1 
ATOM   6603 O  O   . ARG F 6 214 ? 145.459 126.750 168.499 1.00 64.13  ? 228 ARG A O   1 
ATOM   6604 C  CB  . ARG F 6 214 ? 145.590 128.877 171.301 1.00 49.32  ? 228 ARG A CB  1 
ATOM   6605 N  N   . ASP F 6 215 ? 144.678 126.223 170.539 1.00 62.58  ? 229 ASP A N   1 
ATOM   6606 C  CA  . ASP F 6 215 ? 143.897 125.083 170.076 1.00 64.74  ? 229 ASP A CA  1 
ATOM   6607 C  C   . ASP F 6 215 ? 142.526 125.460 169.533 1.00 62.02  ? 229 ASP A C   1 
ATOM   6608 O  O   . ASP F 6 215 ? 141.770 124.564 169.148 1.00 62.05  ? 229 ASP A O   1 
ATOM   6609 C  CB  . ASP F 6 215 ? 143.725 124.071 171.211 1.00 56.53  ? 229 ASP A CB  1 
ATOM   6610 N  N   . GLU F 6 216 ? 142.180 126.742 169.499 1.00 52.77  ? 230 GLU A N   1 
ATOM   6611 C  CA  . GLU F 6 216 ? 140.896 127.179 168.969 1.00 49.68  ? 230 GLU A CA  1 
ATOM   6612 C  C   . GLU F 6 216 ? 141.092 127.717 167.560 1.00 56.55  ? 230 GLU A C   1 
ATOM   6613 O  O   . GLU F 6 216 ? 141.759 128.736 167.364 1.00 67.05  ? 230 GLU A O   1 
ATOM   6614 C  CB  . GLU F 6 216 ? 140.272 128.233 169.875 1.00 58.24  ? 230 GLU A CB  1 
ATOM   6615 C  CG  . GLU F 6 216 ? 140.401 127.904 171.340 1.00 63.41  ? 230 GLU A CG  1 
ATOM   6616 C  CD  . GLU F 6 216 ? 139.100 127.440 171.949 1.00 68.70  ? 230 GLU A CD  1 
ATOM   6617 O  OE1 . GLU F 6 216 ? 139.115 127.011 173.118 1.00 63.70  ? 230 GLU A OE1 1 
ATOM   6618 O  OE2 . GLU F 6 216 ? 138.060 127.507 171.263 1.00 68.91  ? 230 GLU A OE2 1 
ATOM   6619 N  N   . ARG F 6 217 ? 140.490 127.040 166.586 1.00 50.19  ? 231 ARG A N   1 
ATOM   6620 C  CA  . ARG F 6 217 ? 140.775 127.266 165.181 1.00 46.90  ? 231 ARG A CA  1 
ATOM   6621 C  C   . ARG F 6 217 ? 139.750 128.126 164.465 1.00 52.79  ? 231 ARG A C   1 
ATOM   6622 O  O   . ARG F 6 217 ? 140.015 128.556 163.343 1.00 55.85  ? 231 ARG A O   1 
ATOM   6623 C  CB  . ARG F 6 217 ? 140.870 125.923 164.451 1.00 45.91  ? 231 ARG A CB  1 
ATOM   6624 C  CG  . ARG F 6 217 ? 142.258 125.375 164.337 1.00 54.63  ? 231 ARG A CG  1 
ATOM   6625 C  CD  . ARG F 6 217 ? 142.243 123.949 163.861 1.00 48.25  ? 231 ARG A CD  1 
ATOM   6626 N  NE  . ARG F 6 217 ? 142.200 123.009 164.970 1.00 47.62  ? 231 ARG A NE  1 
ATOM   6627 C  CZ  . ARG F 6 217 ? 143.144 122.113 165.219 1.00 57.39  ? 231 ARG A CZ  1 
ATOM   6628 N  NH1 . ARG F 6 217 ? 144.229 122.030 164.470 1.00 55.69  ? 231 ARG A NH1 1 
ATOM   6629 N  NH2 . ARG F 6 217 ? 142.994 121.280 166.242 1.00 57.86  ? 231 ARG A NH2 1 
ATOM   6630 N  N   . ARG F 6 218 ? 138.596 128.395 165.071 1.00 45.61  ? 232 ARG A N   1 
ATOM   6631 C  CA  . ARG F 6 218 ? 137.479 128.939 164.312 1.00 42.17  ? 232 ARG A CA  1 
ATOM   6632 C  C   . ARG F 6 218 ? 137.662 130.393 163.914 1.00 53.19  ? 232 ARG A C   1 
ATOM   6633 O  O   . ARG F 6 218 ? 136.853 130.900 163.131 1.00 60.86  ? 232 ARG A O   1 
ATOM   6634 C  CB  . ARG F 6 218 ? 136.181 128.784 165.099 1.00 44.97  ? 232 ARG A CB  1 
ATOM   6635 C  CG  . ARG F 6 218 ? 135.965 129.803 166.186 1.00 45.54  ? 232 ARG A CG  1 
ATOM   6636 C  CD  . ARG F 6 218 ? 135.339 129.150 167.394 1.00 49.00  ? 232 ARG A CD  1 
ATOM   6637 N  NE  . ARG F 6 218 ? 134.681 130.102 168.276 1.00 48.68  ? 232 ARG A NE  1 
ATOM   6638 C  CZ  . ARG F 6 218 ? 134.741 130.052 169.598 1.00 51.05  ? 232 ARG A CZ  1 
ATOM   6639 N  NH1 . ARG F 6 218 ? 135.445 129.126 170.223 1.00 46.44  ? 232 ARG A NH1 1 
ATOM   6640 N  NH2 . ARG F 6 218 ? 134.075 130.951 170.312 1.00 52.61  ? 232 ARG A NH2 1 
ATOM   6641 N  N   . LYS F 6 219 ? 138.688 131.076 164.415 1.00 59.20  ? 233 LYS A N   1 
ATOM   6642 C  CA  . LYS F 6 219 ? 138.876 132.496 164.147 1.00 49.28  ? 233 LYS A CA  1 
ATOM   6643 C  C   . LYS F 6 219 ? 140.002 132.781 163.169 1.00 48.90  ? 233 LYS A C   1 
ATOM   6644 O  O   . LYS F 6 219 ? 139.847 133.627 162.288 1.00 59.85  ? 233 LYS A O   1 
ATOM   6645 C  CB  . LYS F 6 219 ? 139.126 133.248 165.459 1.00 47.57  ? 233 LYS A CB  1 
ATOM   6646 C  CG  . LYS F 6 219 ? 137.860 133.555 166.229 1.00 52.52  ? 233 LYS A CG  1 
ATOM   6647 C  CD  . LYS F 6 219 ? 136.784 134.089 165.313 1.00 51.59  ? 233 LYS A CD  1 
ATOM   6648 C  CE  . LYS F 6 219 ? 135.506 134.358 166.067 1.00 53.30  ? 233 LYS A CE  1 
ATOM   6649 N  NZ  . LYS F 6 219 ? 134.441 134.843 165.157 1.00 58.56  ? 233 LYS A NZ  1 
ATOM   6650 N  N   . TRP F 6 220 ? 141.140 132.106 163.296 1.00 52.50  ? 234 TRP A N   1 
ATOM   6651 C  CA  . TRP F 6 220 ? 142.233 132.327 162.363 1.00 43.24  ? 234 TRP A CA  1 
ATOM   6652 C  C   . TRP F 6 220 ? 142.198 131.389 161.165 1.00 52.99  ? 234 TRP A C   1 
ATOM   6653 O  O   . TRP F 6 220 ? 143.071 131.493 160.300 1.00 58.95  ? 234 TRP A O   1 
ATOM   6654 C  CB  . TRP F 6 220 ? 143.588 132.206 163.071 1.00 36.94  ? 234 TRP A CB  1 
ATOM   6655 C  CG  . TRP F 6 220 ? 143.875 130.902 163.760 1.00 47.96  ? 234 TRP A CG  1 
ATOM   6656 C  CD1 . TRP F 6 220 ? 143.821 130.661 165.096 1.00 53.96  ? 234 TRP A CD1 1 
ATOM   6657 C  CD2 . TRP F 6 220 ? 144.317 129.678 163.154 1.00 53.57  ? 234 TRP A CD2 1 
ATOM   6658 N  NE1 . TRP F 6 220 ? 144.173 129.365 165.362 1.00 51.10  ? 234 TRP A NE1 1 
ATOM   6659 C  CE2 . TRP F 6 220 ? 144.480 128.740 164.185 1.00 47.92  ? 234 TRP A CE2 1 
ATOM   6660 C  CE3 . TRP F 6 220 ? 144.574 129.282 161.840 1.00 54.74  ? 234 TRP A CE3 1 
ATOM   6661 C  CZ2 . TRP F 6 220 ? 144.892 127.438 163.945 1.00 48.35  ? 234 TRP A CZ2 1 
ATOM   6662 C  CZ3 . TRP F 6 220 ? 144.976 127.987 161.606 1.00 38.32  ? 234 TRP A CZ3 1 
ATOM   6663 C  CH2 . TRP F 6 220 ? 145.121 127.080 162.651 1.00 39.12  ? 234 TRP A CH2 1 
ATOM   6664 N  N   . ILE F 6 221 ? 141.222 130.484 161.087 1.00 55.76  ? 235 ILE A N   1 
ATOM   6665 C  CA  . ILE F 6 221 ? 141.155 129.589 159.938 1.00 49.45  ? 235 ILE A CA  1 
ATOM   6666 C  C   . ILE F 6 221 ? 140.499 130.279 158.756 1.00 57.52  ? 235 ILE A C   1 
ATOM   6667 O  O   . ILE F 6 221 ? 140.698 129.872 157.608 1.00 68.10  ? 235 ILE A O   1 
ATOM   6668 C  CB  . ILE F 6 221 ? 140.414 128.290 160.302 1.00 54.03  ? 235 ILE A CB  1 
ATOM   6669 C  CG1 . ILE F 6 221 ? 140.770 127.170 159.327 1.00 48.61  ? 235 ILE A CG1 1 
ATOM   6670 C  CG2 . ILE F 6 221 ? 138.911 128.512 160.308 1.00 54.10  ? 235 ILE A CG2 1 
ATOM   6671 C  CD1 . ILE F 6 221 ? 142.059 126.484 159.628 1.00 52.64  ? 235 ILE A CD1 1 
ATOM   6672 N  N   . GLN F 6 222 ? 139.722 131.330 158.999 1.00 51.23  ? 236 GLN A N   1 
ATOM   6673 C  CA  . GLN F 6 222 ? 138.969 131.969 157.932 1.00 54.90  ? 236 GLN A CA  1 
ATOM   6674 C  C   . GLN F 6 222 ? 139.757 133.055 157.221 1.00 55.35  ? 236 GLN A C   1 
ATOM   6675 O  O   . GLN F 6 222 ? 139.194 133.752 156.375 1.00 71.06  ? 236 GLN A O   1 
ATOM   6676 C  CB  . GLN F 6 222 ? 137.657 132.543 158.465 1.00 53.92  ? 236 GLN A CB  1 
ATOM   6677 C  CG  . GLN F 6 222 ? 137.797 133.571 159.553 1.00 57.93  ? 236 GLN A CG  1 
ATOM   6678 C  CD  . GLN F 6 222 ? 136.491 133.800 160.273 1.00 62.21  ? 236 GLN A CD  1 
ATOM   6679 O  OE1 . GLN F 6 222 ? 135.659 132.901 160.367 1.00 57.40  ? 236 GLN A OE1 1 
ATOM   6680 N  NE2 . GLN F 6 222 ? 136.298 135.007 160.781 1.00 58.84  ? 236 GLN A NE2 1 
ATOM   6681 N  N   . CYS F 6 223 ? 141.034 133.221 157.548 1.00 47.18  ? 237 CYS A N   1 
ATOM   6682 C  CA  . CYS F 6 223 ? 141.930 134.063 156.775 1.00 56.12  ? 237 CYS A CA  1 
ATOM   6683 C  C   . CYS F 6 223 ? 142.714 133.265 155.746 1.00 54.43  ? 237 CYS A C   1 
ATOM   6684 O  O   . CYS F 6 223 ? 143.628 133.806 155.115 1.00 54.88  ? 237 CYS A O   1 
ATOM   6685 C  CB  . CYS F 6 223 ? 142.875 134.825 157.706 1.00 53.21  ? 237 CYS A CB  1 
ATOM   6686 S  SG  . CYS F 6 223 ? 144.178 133.848 158.440 1.00 67.57  ? 237 CYS A SG  1 
ATOM   6687 N  N   . PHE F 6 224 ? 142.377 131.991 155.568 1.00 56.04  ? 238 PHE A N   1 
ATOM   6688 C  CA  . PHE F 6 224 ? 142.971 131.103 154.577 1.00 50.23  ? 238 PHE A CA  1 
ATOM   6689 C  C   . PHE F 6 224 ? 141.932 130.702 153.546 1.00 49.49  ? 238 PHE A C   1 
ATOM   6690 O  O   . PHE F 6 224 ? 141.945 129.585 153.029 1.00 49.04  ? 238 PHE A O   1 
ATOM   6691 C  CB  . PHE F 6 224 ? 143.561 129.861 155.235 1.00 31.57  ? 238 PHE A CB  1 
ATOM   6692 C  CG  . PHE F 6 224 ? 144.785 130.129 156.053 1.00 37.46  ? 238 PHE A CG  1 
ATOM   6693 C  CD1 . PHE F 6 224 ? 146.021 130.237 155.456 1.00 45.81  ? 238 PHE A CD1 1 
ATOM   6694 C  CD2 . PHE F 6 224 ? 144.701 130.260 157.422 1.00 43.73  ? 238 PHE A CD2 1 
ATOM   6695 C  CE1 . PHE F 6 224 ? 147.141 130.477 156.207 1.00 47.80  ? 238 PHE A CE1 1 
ATOM   6696 C  CE2 . PHE F 6 224 ? 145.820 130.501 158.174 1.00 45.13  ? 238 PHE A CE2 1 
ATOM   6697 C  CZ  . PHE F 6 224 ? 147.039 130.610 157.567 1.00 49.85  ? 238 PHE A CZ  1 
ATOM   6698 N  N   . ASN F 6 225 ? 141.004 131.602 153.243 1.00 46.99  ? 239 ASN A N   1 
ATOM   6699 C  CA  . ASN F 6 225 ? 139.881 131.292 152.372 1.00 42.38  ? 239 ASN A CA  1 
ATOM   6700 C  C   . ASN F 6 225 ? 140.187 131.498 150.896 1.00 46.47  ? 239 ASN A C   1 
ATOM   6701 O  O   . ASN F 6 225 ? 139.362 131.139 150.053 1.00 55.07  ? 239 ASN A O   1 
ATOM   6702 C  CB  . ASN F 6 225 ? 138.667 132.132 152.763 1.00 43.97  ? 239 ASN A CB  1 
ATOM   6703 C  CG  . ASN F 6 225 ? 138.737 133.532 152.216 1.00 58.06  ? 239 ASN A CG  1 
ATOM   6704 O  OD1 . ASN F 6 225 ? 139.745 134.217 152.363 1.00 64.85  ? 239 ASN A OD1 1 
ATOM   6705 N  ND2 . ASN F 6 225 ? 137.663 133.968 151.572 1.00 50.44  ? 239 ASN A ND2 1 
ATOM   6706 N  N   . ASP F 6 226 ? 141.341 132.069 150.559 1.00 42.42  ? 240 ASP A N   1 
ATOM   6707 C  CA  . ASP F 6 226 ? 141.747 132.247 149.171 1.00 39.43  ? 240 ASP A CA  1 
ATOM   6708 C  C   . ASP F 6 226 ? 142.924 131.358 148.800 1.00 49.37  ? 240 ASP A C   1 
ATOM   6709 O  O   . ASP F 6 226 ? 143.515 131.540 147.731 1.00 60.99  ? 240 ASP A O   1 
ATOM   6710 C  CB  . ASP F 6 226 ? 142.089 133.712 148.903 1.00 47.84  ? 240 ASP A CB  1 
ATOM   6711 N  N   . VAL F 6 227 ? 143.282 130.406 149.659 1.00 45.61  ? 241 VAL A N   1 
ATOM   6712 C  CA  . VAL F 6 227 ? 144.394 129.509 149.390 1.00 36.49  ? 241 VAL A CA  1 
ATOM   6713 C  C   . VAL F 6 227 ? 143.978 128.497 148.327 1.00 46.53  ? 241 VAL A C   1 
ATOM   6714 O  O   . VAL F 6 227 ? 142.794 128.172 148.181 1.00 54.67  ? 241 VAL A O   1 
ATOM   6715 C  CB  . VAL F 6 227 ? 144.826 128.842 150.709 1.00 22.35  ? 241 VAL A CB  1 
ATOM   6716 C  CG1 . VAL F 6 227 ? 143.727 127.989 151.289 1.00 35.21  ? 241 VAL A CG1 1 
ATOM   6717 C  CG2 . VAL F 6 227 ? 146.098 128.062 150.529 1.00 43.07  ? 241 VAL A CG2 1 
ATOM   6718 N  N   . THR F 6 228 ? 144.948 128.018 147.540 1.00 40.40  ? 242 THR A N   1 
ATOM   6719 C  CA  . THR F 6 228 ? 144.589 127.142 146.426 1.00 48.51  ? 242 THR A CA  1 
ATOM   6720 C  C   . THR F 6 228 ? 144.174 125.752 146.893 1.00 45.26  ? 242 THR A C   1 
ATOM   6721 O  O   . THR F 6 228 ? 143.250 125.166 146.321 1.00 46.16  ? 242 THR A O   1 
ATOM   6722 C  CB  . THR F 6 228 ? 145.732 127.047 145.401 1.00 45.49  ? 242 THR A CB  1 
ATOM   6723 O  OG1 . THR F 6 228 ? 145.278 126.336 144.244 1.00 50.59  ? 242 THR A OG1 1 
ATOM   6724 C  CG2 . THR F 6 228 ? 146.924 126.317 145.947 1.00 46.25  ? 242 THR A CG2 1 
ATOM   6725 N  N   . ALA F 6 229 ? 144.816 125.219 147.928 1.00 42.68  ? 243 ALA A N   1 
ATOM   6726 C  CA  . ALA F 6 229 ? 144.488 123.900 148.436 1.00 40.59  ? 243 ALA A CA  1 
ATOM   6727 C  C   . ALA F 6 229 ? 144.903 123.813 149.891 1.00 43.02  ? 243 ALA A C   1 
ATOM   6728 O  O   . ALA F 6 229 ? 145.744 124.579 150.358 1.00 46.71  ? 243 ALA A O   1 
ATOM   6729 C  CB  . ALA F 6 229 ? 145.171 122.795 147.631 1.00 37.60  ? 243 ALA A CB  1 
ATOM   6730 N  N   . ILE F 6 230 ? 144.303 122.868 150.599 1.00 42.86  ? 244 ILE A N   1 
ATOM   6731 C  CA  . ILE F 6 230 ? 144.629 122.584 151.988 1.00 43.63  ? 244 ILE A CA  1 
ATOM   6732 C  C   . ILE F 6 230 ? 145.225 121.187 152.049 1.00 44.03  ? 244 ILE A C   1 
ATOM   6733 O  O   . ILE F 6 230 ? 144.610 120.227 151.577 1.00 65.66  ? 244 ILE A O   1 
ATOM   6734 C  CB  . ILE F 6 230 ? 143.381 122.688 152.881 1.00 43.74  ? 244 ILE A CB  1 
ATOM   6735 C  CG1 . ILE F 6 230 ? 142.962 124.143 153.065 1.00 45.01  ? 244 ILE A CG1 1 
ATOM   6736 C  CG2 . ILE F 6 230 ? 143.630 122.059 154.210 1.00 37.37  ? 244 ILE A CG2 1 
ATOM   6737 C  CD1 . ILE F 6 230 ? 141.688 124.308 153.850 1.00 39.19  ? 244 ILE A CD1 1 
ATOM   6738 N  N   . ILE F 6 231 ? 146.420 121.067 152.610 1.00 53.69  ? 245 ILE A N   1 
ATOM   6739 C  CA  . ILE F 6 231 ? 147.073 119.776 152.771 1.00 54.90  ? 245 ILE A CA  1 
ATOM   6740 C  C   . ILE F 6 231 ? 146.796 119.285 154.182 1.00 64.18  ? 245 ILE A C   1 
ATOM   6741 O  O   . ILE F 6 231 ? 147.226 119.906 155.158 1.00 81.66  ? 245 ILE A O   1 
ATOM   6742 C  CB  . ILE F 6 231 ? 148.582 119.866 152.500 1.00 58.20  ? 245 ILE A CB  1 
ATOM   6743 C  CG1 . ILE F 6 231 ? 148.839 120.433 151.110 1.00 63.51  ? 245 ILE A CG1 1 
ATOM   6744 C  CG2 . ILE F 6 231 ? 149.222 118.505 152.632 1.00 61.34  ? 245 ILE A CG2 1 
ATOM   6745 C  CD1 . ILE F 6 231 ? 150.292 120.560 150.778 1.00 64.30  ? 245 ILE A CD1 1 
ATOM   6746 N  N   . PHE F 6 232 ? 146.082 118.173 154.289 1.00 41.38  ? 246 PHE A N   1 
ATOM   6747 C  CA  . PHE F 6 232 ? 145.619 117.630 155.563 1.00 35.98  ? 246 PHE A CA  1 
ATOM   6748 C  C   . PHE F 6 232 ? 146.355 116.319 155.804 1.00 38.38  ? 246 PHE A C   1 
ATOM   6749 O  O   . PHE F 6 232 ? 146.142 115.342 155.082 1.00 60.69  ? 246 PHE A O   1 
ATOM   6750 C  CB  . PHE F 6 232 ? 144.109 117.436 155.533 1.00 36.31  ? 246 PHE A CB  1 
ATOM   6751 C  CG  . PHE F 6 232 ? 143.487 117.257 156.883 1.00 44.51  ? 246 PHE A CG  1 
ATOM   6752 C  CD1 . PHE F 6 232 ? 143.085 118.347 157.623 1.00 55.11  ? 246 PHE A CD1 1 
ATOM   6753 C  CD2 . PHE F 6 232 ? 143.287 115.996 157.405 1.00 48.77  ? 246 PHE A CD2 1 
ATOM   6754 C  CE1 . PHE F 6 232 ? 142.513 118.181 158.860 1.00 54.19  ? 246 PHE A CE1 1 
ATOM   6755 C  CE2 . PHE F 6 232 ? 142.713 115.831 158.641 1.00 45.26  ? 246 PHE A CE2 1 
ATOM   6756 C  CZ  . PHE F 6 232 ? 142.328 116.923 159.366 1.00 44.19  ? 246 PHE A CZ  1 
ATOM   6757 N  N   . VAL F 6 233 ? 147.222 116.288 156.807 1.00 45.99  ? 247 VAL A N   1 
ATOM   6758 C  CA  . VAL F 6 233 ? 147.977 115.085 157.138 1.00 50.26  ? 247 VAL A CA  1 
ATOM   6759 C  C   . VAL F 6 233 ? 147.337 114.425 158.351 1.00 54.71  ? 247 VAL A C   1 
ATOM   6760 O  O   . VAL F 6 233 ? 147.276 115.018 159.432 1.00 65.03  ? 247 VAL A O   1 
ATOM   6761 C  CB  . VAL F 6 233 ? 149.453 115.405 157.402 1.00 47.98  ? 247 VAL A CB  1 
ATOM   6762 C  CG1 . VAL F 6 233 ? 150.250 114.126 157.495 1.00 42.55  ? 247 VAL A CG1 1 
ATOM   6763 C  CG2 . VAL F 6 233 ? 150.002 116.287 156.307 1.00 56.77  ? 247 VAL A CG2 1 
ATOM   6764 N  N   . VAL F 6 234 ? 146.862 113.196 158.175 1.00 47.66  ? 248 VAL A N   1 
ATOM   6765 C  CA  . VAL F 6 234 ? 146.183 112.442 159.220 1.00 52.89  ? 248 VAL A CA  1 
ATOM   6766 C  C   . VAL F 6 234 ? 146.786 111.047 159.264 1.00 52.92  ? 248 VAL A C   1 
ATOM   6767 O  O   . VAL F 6 234 ? 146.895 110.382 158.229 1.00 58.47  ? 248 VAL A O   1 
ATOM   6768 C  CB  . VAL F 6 234 ? 144.667 112.382 158.979 1.00 55.95  ? 248 VAL A CB  1 
ATOM   6769 C  CG1 . VAL F 6 234 ? 144.370 111.649 157.693 1.00 50.25  ? 248 VAL A CG1 1 
ATOM   6770 C  CG2 . VAL F 6 234 ? 143.965 111.713 160.140 1.00 53.38  ? 248 VAL A CG2 1 
ATOM   6771 N  N   . ALA F 6 235 ? 147.179 110.606 160.455 1.00 47.20  ? 249 ALA A N   1 
ATOM   6772 C  CA  . ALA F 6 235 ? 147.750 109.274 160.624 1.00 51.37  ? 249 ALA A CA  1 
ATOM   6773 C  C   . ALA F 6 235 ? 146.668 108.240 160.906 1.00 59.00  ? 249 ALA A C   1 
ATOM   6774 O  O   . ALA F 6 235 ? 146.613 107.190 160.266 1.00 56.44  ? 249 ALA A O   1 
ATOM   6775 C  CB  . ALA F 6 235 ? 148.775 109.276 161.738 1.00 46.17  ? 249 ALA A CB  1 
ATOM   6776 N  N   . ASN F 6 250 ? 140.891 107.407 170.544 1.00 74.68  ? 264 ASN A N   1 
ATOM   6777 C  CA  . ASN F 6 250 ? 140.423 107.491 169.166 1.00 79.62  ? 264 ASN A CA  1 
ATOM   6778 C  C   . ASN F 6 250 ? 140.971 108.731 168.475 1.00 84.87  ? 264 ASN A C   1 
ATOM   6779 O  O   . ASN F 6 250 ? 140.297 109.757 168.398 1.00 78.62  ? 264 ASN A O   1 
ATOM   6780 C  CB  . ASN F 6 250 ? 138.895 107.500 169.114 1.00 79.95  ? 264 ASN A CB  1 
ATOM   6781 C  CG  . ASN F 6 250 ? 138.354 106.873 167.846 1.00 83.71  ? 264 ASN A CG  1 
ATOM   6782 O  OD1 . ASN F 6 250 ? 139.098 106.621 166.902 1.00 81.30  ? 264 ASN A OD1 1 
ATOM   6783 N  ND2 . ASN F 6 250 ? 137.054 106.619 167.818 1.00 85.16  ? 264 ASN A ND2 1 
ATOM   6784 N  N   . ARG F 6 251 ? 142.202 108.632 167.975 1.00 77.74  ? 265 ARG A N   1 
ATOM   6785 C  CA  . ARG F 6 251 ? 142.805 109.744 167.256 1.00 70.06  ? 265 ARG A CA  1 
ATOM   6786 C  C   . ARG F 6 251 ? 142.243 109.909 165.852 1.00 78.30  ? 265 ARG A C   1 
ATOM   6787 O  O   . ARG F 6 251 ? 142.367 110.994 165.277 1.00 81.59  ? 265 ARG A O   1 
ATOM   6788 C  CB  . ARG F 6 251 ? 144.321 109.561 167.182 1.00 72.57  ? 265 ARG A CB  1 
ATOM   6789 C  CG  . ARG F 6 251 ? 145.029 109.540 168.530 1.00 76.58  ? 265 ARG A CG  1 
ATOM   6790 C  CD  . ARG F 6 251 ? 144.902 110.862 169.264 1.00 75.37  ? 265 ARG A CD  1 
ATOM   6791 N  NE  . ARG F 6 251 ? 145.499 111.959 168.511 1.00 79.95  ? 265 ARG A NE  1 
ATOM   6792 C  CZ  . ARG F 6 251 ? 146.794 112.247 168.504 1.00 83.01  ? 265 ARG A CZ  1 
ATOM   6793 N  NH1 . ARG F 6 251 ? 147.664 111.551 169.218 1.00 81.21  ? 265 ARG A NH1 1 
ATOM   6794 N  NH2 . ARG F 6 251 ? 147.228 113.259 167.757 1.00 77.32  ? 265 ARG A NH2 1 
ATOM   6795 N  N   . LEU F 6 252 ? 141.638 108.865 165.287 1.00 71.06  ? 266 LEU A N   1 
ATOM   6796 C  CA  . LEU F 6 252 ? 141.064 108.937 163.948 1.00 65.00  ? 266 LEU A CA  1 
ATOM   6797 C  C   . LEU F 6 252 ? 139.757 109.711 163.903 1.00 68.27  ? 266 LEU A C   1 
ATOM   6798 O  O   . LEU F 6 252 ? 139.522 110.457 162.947 1.00 69.95  ? 266 LEU A O   1 
ATOM   6799 C  CB  . LEU F 6 252 ? 140.825 107.531 163.396 1.00 67.56  ? 266 LEU A CB  1 
ATOM   6800 C  CG  . LEU F 6 252 ? 141.692 107.053 162.232 1.00 65.82  ? 266 LEU A CG  1 
ATOM   6801 C  CD1 . LEU F 6 252 ? 141.043 105.866 161.557 1.00 63.07  ? 266 LEU A CD1 1 
ATOM   6802 C  CD2 . LEU F 6 252 ? 141.916 108.170 161.240 1.00 66.04  ? 266 LEU A CD2 1 
ATOM   6803 N  N   . GLN F 6 253 ? 138.896 109.540 164.906 1.00 68.25  ? 267 GLN A N   1 
ATOM   6804 C  CA  . GLN F 6 253 ? 137.627 110.257 164.904 1.00 68.24  ? 267 GLN A CA  1 
ATOM   6805 C  C   . GLN F 6 253 ? 137.830 111.756 165.064 1.00 69.53  ? 267 GLN A C   1 
ATOM   6806 O  O   . GLN F 6 253 ? 137.043 112.543 164.530 1.00 72.96  ? 267 GLN A O   1 
ATOM   6807 C  CB  . GLN F 6 253 ? 136.716 109.719 166.005 1.00 64.01  ? 267 GLN A CB  1 
ATOM   6808 C  CG  . GLN F 6 253 ? 135.286 110.217 165.923 1.00 66.34  ? 267 GLN A CG  1 
ATOM   6809 C  CD  . GLN F 6 253 ? 134.497 109.559 164.811 1.00 73.76  ? 267 GLN A CD  1 
ATOM   6810 O  OE1 . GLN F 6 253 ? 134.362 108.341 164.771 1.00 73.01  ? 267 GLN A OE1 1 
ATOM   6811 N  NE2 . GLN F 6 253 ? 133.965 110.368 163.907 1.00 68.83  ? 267 GLN A NE2 1 
ATOM   6812 N  N   . GLU F 6 254 ? 138.876 112.175 165.778 1.00 65.25  ? 268 GLU A N   1 
ATOM   6813 C  CA  . GLU F 6 254 ? 139.152 113.602 165.896 1.00 62.98  ? 268 GLU A CA  1 
ATOM   6814 C  C   . GLU F 6 254 ? 139.565 114.197 164.556 1.00 68.08  ? 268 GLU A C   1 
ATOM   6815 O  O   . GLU F 6 254 ? 139.141 115.304 164.203 1.00 65.97  ? 268 GLU A O   1 
ATOM   6816 C  CB  . GLU F 6 254 ? 140.226 113.841 166.952 1.00 62.96  ? 268 GLU A CB  1 
ATOM   6817 C  CG  . GLU F 6 254 ? 140.020 113.056 168.239 1.00 73.74  ? 268 GLU A CG  1 
ATOM   6818 C  CD  . GLU F 6 254 ? 138.627 113.215 168.830 1.00 78.49  ? 268 GLU A CD  1 
ATOM   6819 O  OE1 . GLU F 6 254 ? 138.117 114.354 168.873 1.00 77.88  ? 268 GLU A OE1 1 
ATOM   6820 O  OE2 . GLU F 6 254 ? 138.041 112.196 169.257 1.00 78.78  ? 268 GLU A OE2 1 
ATOM   6821 N  N   . ALA F 6 255 ? 140.385 113.473 163.789 1.00 62.61  ? 269 ALA A N   1 
ATOM   6822 C  CA  . ALA F 6 255 ? 140.744 113.926 162.450 1.00 48.81  ? 269 ALA A CA  1 
ATOM   6823 C  C   . ALA F 6 255 ? 139.531 113.944 161.529 1.00 52.84  ? 269 ALA A C   1 
ATOM   6824 O  O   . ALA F 6 255 ? 139.377 114.860 160.714 1.00 57.76  ? 269 ALA A O   1 
ATOM   6825 C  CB  . ALA F 6 255 ? 141.841 113.038 161.875 1.00 46.66  ? 269 ALA A CB  1 
ATOM   6826 N  N   . LEU F 6 256 ? 138.659 112.941 161.648 1.00 52.61  ? 270 LEU A N   1 
ATOM   6827 C  CA  . LEU F 6 256 ? 137.439 112.925 160.848 1.00 52.66  ? 270 LEU A CA  1 
ATOM   6828 C  C   . LEU F 6 256 ? 136.550 114.118 161.170 1.00 52.35  ? 270 LEU A C   1 
ATOM   6829 O  O   . LEU F 6 256 ? 135.993 114.747 160.266 1.00 57.15  ? 270 LEU A O   1 
ATOM   6830 C  CB  . LEU F 6 256 ? 136.680 111.619 161.078 1.00 52.37  ? 270 LEU A CB  1 
ATOM   6831 C  CG  . LEU F 6 256 ? 137.191 110.372 160.364 1.00 45.03  ? 270 LEU A CG  1 
ATOM   6832 C  CD1 . LEU F 6 256 ? 136.437 109.152 160.831 1.00 52.81  ? 270 LEU A CD1 1 
ATOM   6833 C  CD2 . LEU F 6 256 ? 137.042 110.534 158.882 1.00 49.75  ? 270 LEU A CD2 1 
ATOM   6834 N  N   . ASN F 6 257 ? 136.404 114.445 162.455 1.00 55.96  ? 271 ASN A N   1 
ATOM   6835 C  CA  . ASN F 6 257 ? 135.590 115.589 162.850 1.00 52.06  ? 271 ASN A CA  1 
ATOM   6836 C  C   . ASN F 6 257 ? 136.197 116.907 162.385 1.00 54.90  ? 271 ASN A C   1 
ATOM   6837 O  O   . ASN F 6 257 ? 135.465 117.806 161.956 1.00 55.51  ? 271 ASN A O   1 
ATOM   6838 C  CB  . ASN F 6 257 ? 135.406 115.600 164.364 1.00 60.22  ? 271 ASN A CB  1 
ATOM   6839 C  CG  . ASN F 6 257 ? 134.412 114.564 164.838 1.00 62.21  ? 271 ASN A CG  1 
ATOM   6840 O  OD1 . ASN F 6 257 ? 134.716 113.754 165.709 1.00 60.53  ? 271 ASN A OD1 1 
ATOM   6841 N  ND2 . ASN F 6 257 ? 133.216 114.588 164.272 1.00 59.34  ? 271 ASN A ND2 1 
ATOM   6842 N  N   . LEU F 6 258 ? 137.522 117.044 162.471 1.00 54.59  ? 272 LEU A N   1 
ATOM   6843 C  CA  . LEU F 6 258 ? 138.167 118.255 161.974 1.00 43.93  ? 272 LEU A CA  1 
ATOM   6844 C  C   . LEU F 6 258 ? 137.971 118.407 160.472 1.00 42.53  ? 272 LEU A C   1 
ATOM   6845 O  O   . LEU F 6 258 ? 137.700 119.509 159.982 1.00 49.94  ? 272 LEU A O   1 
ATOM   6846 C  CB  . LEU F 6 258 ? 139.651 118.236 162.329 1.00 46.83  ? 272 LEU A CB  1 
ATOM   6847 C  CG  . LEU F 6 258 ? 140.475 119.457 161.933 1.00 49.16  ? 272 LEU A CG  1 
ATOM   6848 C  CD1 . LEU F 6 258 ? 139.913 120.705 162.568 1.00 47.70  ? 272 LEU A CD1 1 
ATOM   6849 C  CD2 . LEU F 6 258 ? 141.911 119.259 162.340 1.00 49.72  ? 272 LEU A CD2 1 
ATOM   6850 N  N   . PHE F 6 259 ? 138.092 117.310 159.724 1.00 41.99  ? 273 PHE A N   1 
ATOM   6851 C  CA  . PHE F 6 259 ? 137.839 117.361 158.289 1.00 41.59  ? 273 PHE A CA  1 
ATOM   6852 C  C   . PHE F 6 259 ? 136.393 117.736 157.997 1.00 48.64  ? 273 PHE A C   1 
ATOM   6853 O  O   . PHE F 6 259 ? 136.120 118.524 157.086 1.00 45.79  ? 273 PHE A O   1 
ATOM   6854 C  CB  . PHE F 6 259 ? 138.189 116.015 157.655 1.00 41.05  ? 273 PHE A CB  1 
ATOM   6855 C  CG  . PHE F 6 259 ? 137.982 115.967 156.171 1.00 50.11  ? 273 PHE A CG  1 
ATOM   6856 C  CD1 . PHE F 6 259 ? 138.945 116.442 155.311 1.00 50.72  ? 273 PHE A CD1 1 
ATOM   6857 C  CD2 . PHE F 6 259 ? 136.827 115.434 155.637 1.00 50.28  ? 273 PHE A CD2 1 
ATOM   6858 C  CE1 . PHE F 6 259 ? 138.751 116.394 153.955 1.00 48.58  ? 273 PHE A CE1 1 
ATOM   6859 C  CE2 . PHE F 6 259 ? 136.634 115.389 154.282 1.00 35.46  ? 273 PHE A CE2 1 
ATOM   6860 C  CZ  . PHE F 6 259 ? 137.594 115.866 153.443 1.00 41.68  ? 273 PHE A CZ  1 
ATOM   6861 N  N   . LYS F 6 260 ? 135.451 117.186 158.763 1.00 52.52  ? 274 LYS A N   1 
ATOM   6862 C  CA  . LYS F 6 260 ? 134.041 117.468 158.519 1.00 44.58  ? 274 LYS A CA  1 
ATOM   6863 C  C   . LYS F 6 260 ? 133.702 118.921 158.821 1.00 54.06  ? 274 LYS A C   1 
ATOM   6864 O  O   . LYS F 6 260 ? 132.842 119.514 158.161 1.00 59.78  ? 274 LYS A O   1 
ATOM   6865 C  CB  . LYS F 6 260 ? 133.176 116.525 159.351 1.00 46.68  ? 274 LYS A CB  1 
ATOM   6866 C  CG  . LYS F 6 260 ? 131.689 116.779 159.250 1.00 49.88  ? 274 LYS A CG  1 
ATOM   6867 C  CD  . LYS F 6 260 ? 130.903 115.842 160.147 1.00 52.92  ? 274 LYS A CD  1 
ATOM   6868 C  CE  . LYS F 6 260 ? 131.547 114.471 160.230 1.00 59.62  ? 274 LYS A CE  1 
ATOM   6869 N  NZ  . LYS F 6 260 ? 131.436 113.878 161.590 1.00 61.77  ? 274 LYS A NZ  1 
ATOM   6870 N  N   . SER F 6 261 ? 134.351 119.513 159.824 1.00 52.66  ? 275 SER A N   1 
ATOM   6871 C  CA  . SER F 6 261 ? 134.101 120.920 160.121 1.00 44.29  ? 275 SER A CA  1 
ATOM   6872 C  C   . SER F 6 261 ? 134.789 121.854 159.132 1.00 42.13  ? 275 SER A C   1 
ATOM   6873 O  O   . SER F 6 261 ? 134.243 122.914 158.816 1.00 39.01  ? 275 SER A O   1 
ATOM   6874 C  CB  . SER F 6 261 ? 134.542 121.249 161.544 1.00 48.49  ? 275 SER A CB  1 
ATOM   6875 O  OG  . SER F 6 261 ? 135.945 121.166 161.668 1.00 58.98  ? 275 SER A OG  1 
ATOM   6876 N  N   . ILE F 6 262 ? 135.978 121.495 158.643 1.00 48.24  ? 276 ILE A N   1 
ATOM   6877 C  CA  . ILE F 6 262 ? 136.625 122.292 157.601 1.00 44.52  ? 276 ILE A CA  1 
ATOM   6878 C  C   . ILE F 6 262 ? 135.810 122.256 156.315 1.00 55.81  ? 276 ILE A C   1 
ATOM   6879 O  O   . ILE F 6 262 ? 135.619 123.282 155.654 1.00 57.08  ? 276 ILE A O   1 
ATOM   6880 C  CB  . ILE F 6 262 ? 138.062 121.794 157.364 1.00 38.83  ? 276 ILE A CB  1 
ATOM   6881 C  CG1 . ILE F 6 262 ? 138.997 122.310 158.447 1.00 48.93  ? 276 ILE A CG1 1 
ATOM   6882 C  CG2 . ILE F 6 262 ? 138.561 122.236 156.011 1.00 45.40  ? 276 ILE A CG2 1 
ATOM   6883 C  CD1 . ILE F 6 262 ? 140.390 121.786 158.317 1.00 48.76  ? 276 ILE A CD1 1 
ATOM   6884 N  N   . TRP F 6 263 ? 135.312 121.074 155.946 1.00 52.05  ? 277 TRP A N   1 
ATOM   6885 C  CA  . TRP F 6 263 ? 134.604 120.902 154.681 1.00 38.26  ? 277 TRP A CA  1 
ATOM   6886 C  C   . TRP F 6 263 ? 133.358 121.776 154.606 1.00 42.92  ? 277 TRP A C   1 
ATOM   6887 O  O   . TRP F 6 263 ? 133.083 122.385 153.566 1.00 52.33  ? 277 TRP A O   1 
ATOM   6888 C  CB  . TRP F 6 263 ? 134.242 119.427 154.505 1.00 46.08  ? 277 TRP A CB  1 
ATOM   6889 C  CG  . TRP F 6 263 ? 133.853 119.027 153.120 1.00 52.28  ? 277 TRP A CG  1 
ATOM   6890 C  CD1 . TRP F 6 263 ? 132.602 118.729 152.679 1.00 43.21  ? 277 TRP A CD1 1 
ATOM   6891 C  CD2 . TRP F 6 263 ? 134.725 118.855 151.998 1.00 52.57  ? 277 TRP A CD2 1 
ATOM   6892 N  NE1 . TRP F 6 263 ? 132.636 118.396 151.351 1.00 42.99  ? 277 TRP A NE1 1 
ATOM   6893 C  CE2 . TRP F 6 263 ? 133.930 118.465 150.910 1.00 47.69  ? 277 TRP A CE2 1 
ATOM   6894 C  CE3 . TRP F 6 263 ? 136.100 119.000 151.808 1.00 47.54  ? 277 TRP A CE3 1 
ATOM   6895 C  CZ2 . TRP F 6 263 ? 134.461 118.219 149.657 1.00 46.71  ? 277 TRP A CZ2 1 
ATOM   6896 C  CZ3 . TRP F 6 263 ? 136.621 118.756 150.565 1.00 42.49  ? 277 TRP A CZ3 1 
ATOM   6897 C  CH2 . TRP F 6 263 ? 135.808 118.372 149.506 1.00 43.03  ? 277 TRP A CH2 1 
ATOM   6898 N  N   . ASN F 6 264 ? 132.594 121.854 155.692 1.00 52.61  ? 278 ASN A N   1 
ATOM   6899 C  CA  . ASN F 6 264 ? 131.303 122.529 155.705 1.00 54.83  ? 278 ASN A CA  1 
ATOM   6900 C  C   . ASN F 6 264 ? 131.377 123.974 156.181 1.00 61.05  ? 278 ASN A C   1 
ATOM   6901 O  O   . ASN F 6 264 ? 130.333 124.590 156.404 1.00 67.37  ? 278 ASN A O   1 
ATOM   6902 C  CB  . ASN F 6 264 ? 130.316 121.761 156.580 1.00 50.59  ? 278 ASN A CB  1 
ATOM   6903 C  CG  . ASN F 6 264 ? 130.135 120.338 156.134 1.00 52.92  ? 278 ASN A CG  1 
ATOM   6904 O  OD1 . ASN F 6 264 ? 129.347 120.053 155.238 1.00 63.80  ? 278 ASN A OD1 1 
ATOM   6905 N  ND2 . ASN F 6 264 ? 130.853 119.428 156.766 1.00 50.97  ? 278 ASN A ND2 1 
ATOM   6906 N  N   . ASN F 6 265 ? 132.573 124.524 156.354 1.00 56.82  ? 279 ASN A N   1 
ATOM   6907 C  CA  . ASN F 6 265 ? 132.699 125.912 156.769 1.00 46.86  ? 279 ASN A CA  1 
ATOM   6908 C  C   . ASN F 6 265 ? 132.180 126.844 155.683 1.00 54.79  ? 279 ASN A C   1 
ATOM   6909 O  O   . ASN F 6 265 ? 132.295 126.566 154.490 1.00 57.92  ? 279 ASN A O   1 
ATOM   6910 C  CB  . ASN F 6 265 ? 134.151 126.250 157.081 1.00 50.99  ? 279 ASN A CB  1 
ATOM   6911 C  CG  . ASN F 6 265 ? 134.289 127.497 157.917 1.00 57.82  ? 279 ASN A CG  1 
ATOM   6912 O  OD1 . ASN F 6 265 ? 133.302 128.053 158.390 1.00 58.39  ? 279 ASN A OD1 1 
ATOM   6913 N  ND2 . ASN F 6 265 ? 135.519 127.950 158.100 1.00 65.64  ? 279 ASN A ND2 1 
ATOM   6914 N  N   . ARG F 6 266 ? 131.604 127.965 156.114 1.00 62.53  ? 280 ARG A N   1 
ATOM   6915 C  CA  . ARG F 6 266 ? 131.017 128.918 155.182 1.00 50.75  ? 280 ARG A CA  1 
ATOM   6916 C  C   . ARG F 6 266 ? 132.067 129.615 154.327 1.00 51.89  ? 280 ARG A C   1 
ATOM   6917 O  O   . ARG F 6 266 ? 131.782 129.984 153.184 1.00 63.53  ? 280 ARG A O   1 
ATOM   6918 C  CB  . ARG F 6 266 ? 130.190 129.948 155.950 1.00 54.81  ? 280 ARG A CB  1 
ATOM   6919 C  CG  . ARG F 6 266 ? 129.755 131.135 155.126 1.00 58.16  ? 280 ARG A CG  1 
ATOM   6920 C  CD  . ARG F 6 266 ? 128.467 131.752 155.643 1.00 63.67  ? 280 ARG A CD  1 
ATOM   6921 N  NE  . ARG F 6 266 ? 128.256 133.122 155.182 1.00 69.92  ? 280 ARG A NE  1 
ATOM   6922 C  CZ  . ARG F 6 266 ? 128.193 133.506 153.913 1.00 72.02  ? 280 ARG A CZ  1 
ATOM   6923 N  NH1 . ARG F 6 266 ? 128.314 132.643 152.916 1.00 63.28  ? 280 ARG A NH1 1 
ATOM   6924 N  NH2 . ARG F 6 266 ? 127.998 134.791 153.635 1.00 66.70  ? 280 ARG A NH2 1 
ATOM   6925 N  N   . TRP F 6 267 ? 133.281 129.788 154.843 1.00 47.65  ? 281 TRP A N   1 
ATOM   6926 C  CA  . TRP F 6 267 ? 134.319 130.509 154.124 1.00 44.88  ? 281 TRP A CA  1 
ATOM   6927 C  C   . TRP F 6 267 ? 135.311 129.600 153.418 1.00 56.82  ? 281 TRP A C   1 
ATOM   6928 O  O   . TRP F 6 267 ? 135.974 130.049 152.478 1.00 60.28  ? 281 TRP A O   1 
ATOM   6929 C  CB  . TRP F 6 267 ? 135.061 131.442 155.086 1.00 48.91  ? 281 TRP A CB  1 
ATOM   6930 C  CG  . TRP F 6 267 ? 134.115 132.298 155.858 1.00 57.11  ? 281 TRP A CG  1 
ATOM   6931 C  CD1 . TRP F 6 267 ? 133.859 132.240 157.191 1.00 56.68  ? 281 TRP A CD1 1 
ATOM   6932 C  CD2 . TRP F 6 267 ? 133.269 133.325 155.333 1.00 56.71  ? 281 TRP A CD2 1 
ATOM   6933 N  NE1 . TRP F 6 267 ? 132.914 133.171 157.533 1.00 55.09  ? 281 TRP A NE1 1 
ATOM   6934 C  CE2 . TRP F 6 267 ? 132.535 133.850 156.407 1.00 52.62  ? 281 TRP A CE2 1 
ATOM   6935 C  CE3 . TRP F 6 267 ? 133.065 133.852 154.057 1.00 51.75  ? 281 TRP A CE3 1 
ATOM   6936 C  CZ2 . TRP F 6 267 ? 131.616 134.873 156.244 1.00 51.00  ? 281 TRP A CZ2 1 
ATOM   6937 C  CZ3 . TRP F 6 267 ? 132.154 134.864 153.900 1.00 44.93  ? 281 TRP A CZ3 1 
ATOM   6938 C  CH2 . TRP F 6 267 ? 131.440 135.365 154.984 1.00 53.05  ? 281 TRP A CH2 1 
ATOM   6939 N  N   . LEU F 6 268 ? 135.425 128.342 153.838 1.00 62.07  ? 282 LEU A N   1 
ATOM   6940 C  CA  . LEU F 6 268 ? 136.266 127.355 153.176 1.00 51.39  ? 282 LEU A CA  1 
ATOM   6941 C  C   . LEU F 6 268 ? 135.434 126.371 152.364 1.00 53.71  ? 282 LEU A C   1 
ATOM   6942 O  O   . LEU F 6 268 ? 135.757 125.185 152.293 1.00 54.23  ? 282 LEU A O   1 
ATOM   6943 C  CB  . LEU F 6 268 ? 137.125 126.611 154.196 1.00 43.84  ? 282 LEU A CB  1 
ATOM   6944 C  CG  . LEU F 6 268 ? 137.761 127.437 155.311 1.00 40.79  ? 282 LEU A CG  1 
ATOM   6945 C  CD1 . LEU F 6 268 ? 138.150 126.544 156.462 1.00 39.74  ? 282 LEU A CD1 1 
ATOM   6946 C  CD2 . LEU F 6 268 ? 138.966 128.175 154.795 1.00 45.79  ? 282 LEU A CD2 1 
ATOM   6947 N  N   . ARG F 6 269 ? 134.356 126.854 151.751 1.00 52.39  ? 283 ARG A N   1 
ATOM   6948 C  CA  . ARG F 6 269 ? 133.423 126.007 151.027 1.00 50.41  ? 283 ARG A CA  1 
ATOM   6949 C  C   . ARG F 6 269 ? 133.766 125.858 149.553 1.00 59.58  ? 283 ARG A C   1 
ATOM   6950 O  O   . ARG F 6 269 ? 133.033 125.178 148.828 1.00 67.25  ? 283 ARG A O   1 
ATOM   6951 C  CB  . ARG F 6 269 ? 132.005 126.564 151.158 1.00 55.62  ? 283 ARG A CB  1 
ATOM   6952 C  CG  . ARG F 6 269 ? 130.926 125.510 151.244 1.00 65.35  ? 283 ARG A CG  1 
ATOM   6953 C  CD  . ARG F 6 269 ? 129.974 125.789 152.386 1.00 63.81  ? 283 ARG A CD  1 
ATOM   6954 N  NE  . ARG F 6 269 ? 129.046 126.865 152.061 1.00 67.25  ? 283 ARG A NE  1 
ATOM   6955 C  CZ  . ARG F 6 269 ? 128.126 127.338 152.888 1.00 69.21  ? 283 ARG A CZ  1 
ATOM   6956 N  NH1 . ARG F 6 269 ? 127.974 126.847 154.106 1.00 62.03  ? 283 ARG A NH1 1 
ATOM   6957 N  NH2 . ARG F 6 269 ? 127.338 128.329 152.483 1.00 69.36  ? 283 ARG A NH2 1 
ATOM   6958 N  N   . THR F 6 270 ? 134.837 126.495 149.086 1.00 46.78  ? 284 THR A N   1 
ATOM   6959 C  CA  . THR F 6 270 ? 135.334 126.306 147.731 1.00 43.28  ? 284 THR A CA  1 
ATOM   6960 C  C   . THR F 6 270 ? 136.812 125.944 147.706 1.00 50.28  ? 284 THR A C   1 
ATOM   6961 O  O   . THR F 6 270 ? 137.469 126.140 146.680 1.00 57.04  ? 284 THR A O   1 
ATOM   6962 C  CB  . THR F 6 270 ? 135.094 127.556 146.884 1.00 58.46  ? 284 THR A CB  1 
ATOM   6963 O  OG1 . THR F 6 270 ? 136.013 128.583 147.272 1.00 69.02  ? 284 THR A OG1 1 
ATOM   6964 C  CG2 . THR F 6 270 ? 133.678 128.068 147.057 1.00 54.42  ? 284 THR A CG2 1 
ATOM   6965 N  N   . ILE F 6 271 ? 137.349 125.425 148.806 1.00 53.61  ? 285 ILE A N   1 
ATOM   6966 C  CA  . ILE F 6 271 ? 138.751 125.035 148.909 1.00 51.49  ? 285 ILE A CA  1 
ATOM   6967 C  C   . ILE F 6 271 ? 138.849 123.522 148.807 1.00 53.07  ? 285 ILE A C   1 
ATOM   6968 O  O   . ILE F 6 271 ? 138.112 122.794 149.481 1.00 59.45  ? 285 ILE A O   1 
ATOM   6969 C  CB  . ILE F 6 271 ? 139.378 125.532 150.226 1.00 48.42  ? 285 ILE A CB  1 
ATOM   6970 C  CG1 . ILE F 6 271 ? 139.046 127.001 150.468 1.00 44.18  ? 285 ILE A CG1 1 
ATOM   6971 C  CG2 . ILE F 6 271 ? 140.874 125.341 150.207 1.00 45.14  ? 285 ILE A CG2 1 
ATOM   6972 C  CD1 . ILE F 6 271 ? 139.764 127.935 149.554 1.00 39.89  ? 285 ILE A CD1 1 
ATOM   6973 N  N   . SER F 6 272 ? 139.750 123.046 147.956 1.00 47.96  ? 286 SER A N   1 
ATOM   6974 C  CA  . SER F 6 272 ? 140.015 121.628 147.793 1.00 37.90  ? 286 SER A CA  1 
ATOM   6975 C  C   . SER F 6 272 ? 140.993 121.155 148.856 1.00 45.63  ? 286 SER A C   1 
ATOM   6976 O  O   . SER F 6 272 ? 141.752 121.940 149.423 1.00 57.75  ? 286 SER A O   1 
ATOM   6977 C  CB  . SER F 6 272 ? 140.576 121.338 146.402 1.00 45.98  ? 286 SER A CB  1 
ATOM   6978 O  OG  . SER F 6 272 ? 139.607 121.583 145.403 1.00 54.74  ? 286 SER A OG  1 
ATOM   6979 N  N   . VAL F 6 273 ? 140.970 119.854 149.125 1.00 38.79  ? 287 VAL A N   1 
ATOM   6980 C  CA  . VAL F 6 273 ? 141.788 119.253 150.170 1.00 39.31  ? 287 VAL A CA  1 
ATOM   6981 C  C   . VAL F 6 273 ? 142.637 118.153 149.554 1.00 32.77  ? 287 VAL A C   1 
ATOM   6982 O  O   . VAL F 6 273 ? 142.118 117.291 148.839 1.00 52.56  ? 287 VAL A O   1 
ATOM   6983 C  CB  . VAL F 6 273 ? 140.923 118.701 151.317 1.00 42.79  ? 287 VAL A CB  1 
ATOM   6984 C  CG1 . VAL F 6 273 ? 141.796 118.135 152.408 1.00 39.82  ? 287 VAL A CG1 1 
ATOM   6985 C  CG2 . VAL F 6 273 ? 140.035 119.783 151.876 1.00 39.95  ? 287 VAL A CG2 1 
ATOM   6986 N  N   . ILE F 6 274 ? 143.935 118.189 149.822 1.00 25.66  ? 288 ILE A N   1 
ATOM   6987 C  CA  . ILE F 6 274 ? 144.842 117.106 149.463 1.00 37.08  ? 288 ILE A CA  1 
ATOM   6988 C  C   . ILE F 6 274 ? 145.136 116.316 150.729 1.00 42.35  ? 288 ILE A C   1 
ATOM   6989 O  O   . ILE F 6 274 ? 145.788 116.822 151.644 1.00 58.12  ? 288 ILE A O   1 
ATOM   6990 C  CB  . ILE F 6 274 ? 146.138 117.645 148.841 1.00 44.46  ? 288 ILE A CB  1 
ATOM   6991 C  CG1 . ILE F 6 274 ? 145.834 118.516 147.627 1.00 40.66  ? 288 ILE A CG1 1 
ATOM   6992 C  CG2 . ILE F 6 274 ? 147.064 116.510 148.469 1.00 44.92  ? 288 ILE A CG2 1 
ATOM   6993 C  CD1 . ILE F 6 274 ? 147.028 119.248 147.111 1.00 39.37  ? 288 ILE A CD1 1 
ATOM   6994 N  N   . LEU F 6 275 ? 144.667 115.077 150.781 1.00 46.90  ? 289 LEU A N   1 
ATOM   6995 C  CA  . LEU F 6 275 ? 144.687 114.286 152.002 1.00 44.72  ? 289 LEU A CA  1 
ATOM   6996 C  C   . LEU F 6 275 ? 145.833 113.287 151.955 1.00 39.18  ? 289 LEU A C   1 
ATOM   6997 O  O   . LEU F 6 275 ? 145.946 112.516 151.001 1.00 57.99  ? 289 LEU A O   1 
ATOM   6998 C  CB  . LEU F 6 275 ? 143.352 113.566 152.187 1.00 48.45  ? 289 LEU A CB  1 
ATOM   6999 C  CG  . LEU F 6 275 ? 143.078 112.855 153.508 1.00 53.58  ? 289 LEU A CG  1 
ATOM   7000 C  CD1 . LEU F 6 275 ? 142.476 113.817 154.500 1.00 48.34  ? 289 LEU A CD1 1 
ATOM   7001 C  CD2 . LEU F 6 275 ? 142.147 111.690 153.271 1.00 50.43  ? 289 LEU A CD2 1 
ATOM   7002 N  N   . PHE F 6 276 ? 146.676 113.302 152.983 1.00 34.48  ? 290 PHE A N   1 
ATOM   7003 C  CA  . PHE F 6 276 ? 147.829 112.410 153.082 1.00 50.21  ? 290 PHE A CA  1 
ATOM   7004 C  C   . PHE F 6 276 ? 147.598 111.442 154.236 1.00 51.98  ? 290 PHE A C   1 
ATOM   7005 O  O   . PHE F 6 276 ? 147.721 111.823 155.402 1.00 63.26  ? 290 PHE A O   1 
ATOM   7006 C  CB  . PHE F 6 276 ? 149.121 113.192 153.297 1.00 55.20  ? 290 PHE A CB  1 
ATOM   7007 C  CG  . PHE F 6 276 ? 149.688 113.799 152.050 1.00 51.86  ? 290 PHE A CG  1 
ATOM   7008 C  CD1 . PHE F 6 276 ? 149.846 113.049 150.908 1.00 63.71  ? 290 PHE A CD1 1 
ATOM   7009 C  CD2 . PHE F 6 276 ? 150.095 115.113 152.034 1.00 54.53  ? 290 PHE A CD2 1 
ATOM   7010 C  CE1 . PHE F 6 276 ? 150.376 113.603 149.772 1.00 61.67  ? 290 PHE A CE1 1 
ATOM   7011 C  CE2 . PHE F 6 276 ? 150.626 115.667 150.899 1.00 58.70  ? 290 PHE A CE2 1 
ATOM   7012 C  CZ  . PHE F 6 276 ? 150.765 114.912 149.767 1.00 54.33  ? 290 PHE A CZ  1 
ATOM   7013 N  N   . LEU F 6 277 ? 147.279 110.189 153.922 1.00 56.87  ? 291 LEU A N   1 
ATOM   7014 C  CA  . LEU F 6 277 ? 147.146 109.161 154.948 1.00 54.73  ? 291 LEU A CA  1 
ATOM   7015 C  C   . LEU F 6 277 ? 148.531 108.650 155.313 1.00 54.56  ? 291 LEU A C   1 
ATOM   7016 O  O   . LEU F 6 277 ? 149.116 107.849 154.581 1.00 69.76  ? 291 LEU A O   1 
ATOM   7017 C  CB  . LEU F 6 277 ? 146.257 108.024 154.455 1.00 59.03  ? 291 LEU A CB  1 
ATOM   7018 C  CG  . LEU F 6 277 ? 144.781 108.304 154.165 1.00 55.50  ? 291 LEU A CG  1 
ATOM   7019 C  CD1 . LEU F 6 277 ? 144.113 107.093 153.552 1.00 61.25  ? 291 LEU A CD1 1 
ATOM   7020 C  CD2 . LEU F 6 277 ? 144.049 108.743 155.412 1.00 48.32  ? 291 LEU A CD2 1 
ATOM   7021 N  N   . ASN F 6 278 ? 149.055 109.098 156.449 1.00 52.77  ? 292 ASN A N   1 
ATOM   7022 C  CA  . ASN F 6 278 ? 150.454 108.862 156.783 1.00 62.41  ? 292 ASN A CA  1 
ATOM   7023 C  C   . ASN F 6 278 ? 150.715 107.487 157.376 1.00 68.00  ? 292 ASN A C   1 
ATOM   7024 O  O   . ASN F 6 278 ? 151.874 107.161 157.650 1.00 59.22  ? 292 ASN A O   1 
ATOM   7025 C  CB  . ASN F 6 278 ? 150.945 109.932 157.756 1.00 63.93  ? 292 ASN A CB  1 
ATOM   7026 C  CG  . ASN F 6 278 ? 152.296 110.474 157.376 1.00 66.55  ? 292 ASN A CG  1 
ATOM   7027 O  OD1 . ASN F 6 278 ? 152.618 110.588 156.197 1.00 65.96  ? 292 ASN A OD1 1 
ATOM   7028 N  ND2 . ASN F 6 278 ? 153.101 110.807 158.373 1.00 67.15  ? 292 ASN A ND2 1 
ATOM   7029 N  N   . LYS F 6 279 ? 149.684 106.682 157.588 1.00 78.99  ? 293 LYS A N   1 
ATOM   7030 C  CA  . LYS F 6 279 ? 149.830 105.359 158.183 1.00 83.47  ? 293 LYS A CA  1 
ATOM   7031 C  C   . LYS F 6 279 ? 149.869 104.320 157.069 1.00 88.54  ? 293 LYS A C   1 
ATOM   7032 O  O   . LYS F 6 279 ? 148.901 104.169 156.315 1.00 88.01  ? 293 LYS A O   1 
ATOM   7033 C  CB  . LYS F 6 279 ? 148.688 105.078 159.157 1.00 80.08  ? 293 LYS A CB  1 
ATOM   7034 N  N   . GLN F 6 280 ? 150.983 103.600 156.972 1.00 90.06  ? 294 GLN A N   1 
ATOM   7035 C  CA  . GLN F 6 280 ? 151.121 102.527 155.997 1.00 89.44  ? 294 GLN A CA  1 
ATOM   7036 C  C   . GLN F 6 280 ? 152.344 101.674 156.311 1.00 91.06  ? 294 GLN A C   1 
ATOM   7037 O  O   . GLN F 6 280 ? 152.888 101.733 157.415 1.00 86.18  ? 294 GLN A O   1 
ATOM   7038 C  CB  . GLN F 6 280 ? 151.216 103.091 154.576 1.00 86.46  ? 294 GLN A CB  1 
ATOM   7039 N  N   . ILE F 6 294 ? 140.512 97.106  165.366 1.00 111.82 ? 308 ILE A N   1 
ATOM   7040 C  CA  . ILE F 6 294 ? 140.150 98.114  164.378 1.00 114.89 ? 308 ILE A CA  1 
ATOM   7041 C  C   . ILE F 6 294 ? 138.639 98.150  164.201 1.00 113.78 ? 308 ILE A C   1 
ATOM   7042 O  O   . ILE F 6 294 ? 138.082 99.151  163.760 1.00 110.02 ? 308 ILE A O   1 
ATOM   7043 C  CB  . ILE F 6 294 ? 140.855 97.858  163.030 1.00 111.63 ? 308 ILE A CB  1 
ATOM   7044 N  N   . GLU F 6 295 ? 137.979 97.043  164.538 1.00 106.74 ? 309 GLU A N   1 
ATOM   7045 C  CA  . GLU F 6 295 ? 136.525 96.976  164.510 1.00 104.44 ? 309 GLU A CA  1 
ATOM   7046 C  C   . GLU F 6 295 ? 135.889 97.396  165.826 1.00 105.16 ? 309 GLU A C   1 
ATOM   7047 O  O   . GLU F 6 295 ? 134.669 97.585  165.873 1.00 106.89 ? 309 GLU A O   1 
ATOM   7048 C  CB  . GLU F 6 295 ? 136.062 95.558  164.158 1.00 103.31 ? 309 GLU A CB  1 
ATOM   7049 N  N   . ASP F 6 296 ? 136.678 97.540  166.890 1.00 96.78  ? 310 ASP A N   1 
ATOM   7050 C  CA  . ASP F 6 296 ? 136.129 97.971  168.170 1.00 96.69  ? 310 ASP A CA  1 
ATOM   7051 C  C   . ASP F 6 296 ? 135.763 99.449  168.148 1.00 97.80  ? 310 ASP A C   1 
ATOM   7052 O  O   . ASP F 6 296 ? 134.785 99.857  168.783 1.00 98.12  ? 310 ASP A O   1 
ATOM   7053 C  CB  . ASP F 6 296 ? 137.126 97.683  169.290 1.00 96.41  ? 310 ASP A CB  1 
ATOM   7054 N  N   . TYR F 6 297 ? 136.533 100.263 167.431 1.00 95.57  ? 311 TYR A N   1 
ATOM   7055 C  CA  . TYR F 6 297 ? 136.246 101.684 167.310 1.00 94.11  ? 311 TYR A CA  1 
ATOM   7056 C  C   . TYR F 6 297 ? 135.451 102.029 166.060 1.00 94.07  ? 311 TYR A C   1 
ATOM   7057 O  O   . TYR F 6 297 ? 134.842 103.101 166.015 1.00 97.53  ? 311 TYR A O   1 
ATOM   7058 C  CB  . TYR F 6 297 ? 137.549 102.488 167.325 1.00 90.38  ? 311 TYR A CB  1 
ATOM   7059 N  N   . PHE F 6 298 ? 135.443 101.161 165.050 1.00 88.65  ? 312 PHE A N   1 
ATOM   7060 C  CA  . PHE F 6 298 ? 134.673 101.384 163.828 1.00 90.04  ? 312 PHE A CA  1 
ATOM   7061 C  C   . PHE F 6 298 ? 133.896 100.118 163.500 1.00 91.17  ? 312 PHE A C   1 
ATOM   7062 O  O   . PHE F 6 298 ? 134.355 99.276  162.719 1.00 96.45  ? 312 PHE A O   1 
ATOM   7063 C  CB  . PHE F 6 298 ? 135.578 101.787 162.666 1.00 90.48  ? 312 PHE A CB  1 
ATOM   7064 C  CG  . PHE F 6 298 ? 136.090 103.191 162.763 1.00 89.60  ? 312 PHE A CG  1 
ATOM   7065 C  CD1 . PHE F 6 298 ? 135.278 104.260 162.447 1.00 89.98  ? 312 PHE A CD1 1 
ATOM   7066 C  CD2 . PHE F 6 298 ? 137.381 103.441 163.182 1.00 87.94  ? 312 PHE A CD2 1 
ATOM   7067 C  CE1 . PHE F 6 298 ? 135.744 105.548 162.543 1.00 90.05  ? 312 PHE A CE1 1 
ATOM   7068 C  CE2 . PHE F 6 298 ? 137.849 104.726 163.279 1.00 89.33  ? 312 PHE A CE2 1 
ATOM   7069 C  CZ  . PHE F 6 298 ? 137.030 105.781 162.960 1.00 90.30  ? 312 PHE A CZ  1 
ATOM   7070 N  N   . PRO F 6 299 ? 132.704 99.951  164.077 1.00 88.45  ? 313 PRO A N   1 
ATOM   7071 C  CA  . PRO F 6 299 ? 131.964 98.694  163.921 1.00 88.71  ? 313 PRO A CA  1 
ATOM   7072 C  C   . PRO F 6 299 ? 131.489 98.406  162.506 1.00 92.07  ? 313 PRO A C   1 
ATOM   7073 O  O   . PRO F 6 299 ? 131.120 97.262  162.223 1.00 91.19  ? 313 PRO A O   1 
ATOM   7074 C  CB  . PRO F 6 299 ? 130.765 98.875  164.869 1.00 87.28  ? 313 PRO A CB  1 
ATOM   7075 C  CG  . PRO F 6 299 ? 131.055 100.101 165.674 1.00 88.38  ? 313 PRO A CG  1 
ATOM   7076 C  CD  . PRO F 6 299 ? 131.943 100.947 164.842 1.00 92.57  ? 313 PRO A CD  1 
ATOM   7077 N  N   . GLU F 6 300 ? 131.477 99.391  161.614 1.00 90.80  ? 314 GLU A N   1 
ATOM   7078 C  CA  . GLU F 6 300 ? 131.062 99.176  160.236 1.00 87.76  ? 314 GLU A CA  1 
ATOM   7079 C  C   . GLU F 6 300 ? 132.103 98.426  159.420 1.00 88.77  ? 314 GLU A C   1 
ATOM   7080 O  O   . GLU F 6 300 ? 131.832 98.069  158.272 1.00 85.97  ? 314 GLU A O   1 
ATOM   7081 C  CB  . GLU F 6 300 ? 130.749 100.513 159.560 1.00 90.59  ? 314 GLU A CB  1 
ATOM   7082 C  CG  . GLU F 6 300 ? 130.067 101.524 160.464 1.00 92.78  ? 314 GLU A CG  1 
ATOM   7083 C  CD  . GLU F 6 300 ? 131.030 102.564 161.003 1.00 95.73  ? 314 GLU A CD  1 
ATOM   7084 O  OE1 . GLU F 6 300 ? 131.863 103.065 160.221 1.00 92.84  ? 314 GLU A OE1 1 
ATOM   7085 O  OE2 . GLU F 6 300 ? 130.956 102.877 162.209 1.00 94.25  ? 314 GLU A OE2 1 
ATOM   7086 N  N   . PHE F 6 301 ? 133.287 98.194  159.982 1.00 88.15  ? 315 PHE A N   1 
ATOM   7087 C  CA  . PHE F 6 301 ? 134.349 97.473  159.298 1.00 86.87  ? 315 PHE A CA  1 
ATOM   7088 C  C   . PHE F 6 301 ? 134.049 95.993  159.121 1.00 92.26  ? 315 PHE A C   1 
ATOM   7089 O  O   . PHE F 6 301 ? 134.627 95.366  158.228 1.00 96.60  ? 315 PHE A O   1 
ATOM   7090 C  CB  . PHE F 6 301 ? 135.659 97.636  160.066 1.00 85.17  ? 315 PHE A CB  1 
ATOM   7091 C  CG  . PHE F 6 301 ? 136.865 97.163  159.318 1.00 89.43  ? 315 PHE A CG  1 
ATOM   7092 C  CD1 . PHE F 6 301 ? 137.213 97.732  158.109 1.00 88.73  ? 315 PHE A CD1 1 
ATOM   7093 C  CD2 . PHE F 6 301 ? 137.656 96.153  159.828 1.00 88.16  ? 315 PHE A CD2 1 
ATOM   7094 C  CE1 . PHE F 6 301 ? 138.324 97.304  157.422 1.00 84.51  ? 315 PHE A CE1 1 
ATOM   7095 C  CE2 . PHE F 6 301 ? 138.768 95.721  159.144 1.00 91.72  ? 315 PHE A CE2 1 
ATOM   7096 C  CZ  . PHE F 6 301 ? 139.101 96.300  157.940 1.00 89.56  ? 315 PHE A CZ  1 
ATOM   7097 N  N   . ALA F 6 302 ? 133.168 95.419  159.941 1.00 93.64  ? 316 ALA A N   1 
ATOM   7098 C  CA  . ALA F 6 302 ? 132.926 93.984  159.867 1.00 91.93  ? 316 ALA A CA  1 
ATOM   7099 C  C   . ALA F 6 302 ? 132.216 93.603  158.575 1.00 93.44  ? 316 ALA A C   1 
ATOM   7100 O  O   . ALA F 6 302 ? 132.288 92.449  158.138 1.00 98.46  ? 316 ALA A O   1 
ATOM   7101 C  CB  . ALA F 6 302 ? 132.120 93.525  161.080 1.00 91.67  ? 316 ALA A CB  1 
ATOM   7102 N  N   . ARG F 6 303 ? 131.530 94.554  157.946 1.00 87.11  ? 317 ARG A N   1 
ATOM   7103 C  CA  . ARG F 6 303 ? 130.756 94.304  156.732 1.00 90.26  ? 317 ARG A CA  1 
ATOM   7104 C  C   . ARG F 6 303 ? 131.320 95.047  155.530 1.00 94.64  ? 317 ARG A C   1 
ATOM   7105 O  O   . ARG F 6 303 ? 130.601 95.315  154.565 1.00 97.32  ? 317 ARG A O   1 
ATOM   7106 C  CB  . ARG F 6 303 ? 129.295 94.681  156.952 1.00 89.06  ? 317 ARG A CB  1 
ATOM   7107 N  N   . TYR F 6 304 ? 132.603 95.393  155.563 1.00 88.32  ? 318 TYR A N   1 
ATOM   7108 C  CA  . TYR F 6 304 ? 133.247 96.148  154.495 1.00 86.91  ? 318 TYR A CA  1 
ATOM   7109 C  C   . TYR F 6 304 ? 134.173 95.221  153.726 1.00 89.20  ? 318 TYR A C   1 
ATOM   7110 O  O   . TYR F 6 304 ? 134.995 94.520  154.327 1.00 87.91  ? 318 TYR A O   1 
ATOM   7111 C  CB  . TYR F 6 304 ? 134.024 97.341  155.056 1.00 85.82  ? 318 TYR A CB  1 
ATOM   7112 C  CG  . TYR F 6 304 ? 134.808 98.103  154.015 1.00 84.94  ? 318 TYR A CG  1 
ATOM   7113 C  CD1 . TYR F 6 304 ? 134.198 99.072  153.236 1.00 85.44  ? 318 TYR A CD1 1 
ATOM   7114 C  CD2 . TYR F 6 304 ? 136.155 97.856  153.812 1.00 86.86  ? 318 TYR A CD2 1 
ATOM   7115 C  CE1 . TYR F 6 304 ? 134.904 99.767  152.283 1.00 85.42  ? 318 TYR A CE1 1 
ATOM   7116 C  CE2 . TYR F 6 304 ? 136.869 98.546  152.862 1.00 87.65  ? 318 TYR A CE2 1 
ATOM   7117 C  CZ  . TYR F 6 304 ? 136.237 99.501  152.100 1.00 86.22  ? 318 TYR A CZ  1 
ATOM   7118 O  OH  . TYR F 6 304 ? 136.940 100.199 151.149 1.00 85.97  ? 318 TYR A OH  1 
ATOM   7119 N  N   . THR F 6 305 ? 134.037 95.215  152.403 1.00 89.87  ? 319 THR A N   1 
ATOM   7120 C  CA  . THR F 6 305 ? 134.891 94.437  151.516 1.00 88.65  ? 319 THR A CA  1 
ATOM   7121 C  C   . THR F 6 305 ? 135.549 95.379  150.520 1.00 89.18  ? 319 THR A C   1 
ATOM   7122 O  O   . THR F 6 305 ? 134.873 96.217  149.917 1.00 90.28  ? 319 THR A O   1 
ATOM   7123 C  CB  . THR F 6 305 ? 134.094 93.362  150.773 1.00 92.06  ? 319 THR A CB  1 
ATOM   7124 O  OG1 . THR F 6 305 ? 133.341 93.969  149.716 1.00 98.19  ? 319 THR A OG1 1 
ATOM   7125 C  CG2 . THR F 6 305 ? 133.145 92.645  151.722 1.00 88.63  ? 319 THR A CG2 1 
ATOM   7126 N  N   . THR F 6 306 ? 136.859 95.237  150.352 1.00 92.89  ? 320 THR A N   1 
ATOM   7127 C  CA  . THR F 6 306 ? 137.624 96.113  149.472 1.00 94.71  ? 320 THR A CA  1 
ATOM   7128 C  C   . THR F 6 306 ? 137.166 96.012  148.022 1.00 93.50  ? 320 THR A C   1 
ATOM   7129 O  O   . THR F 6 306 ? 136.940 97.028  147.362 1.00 90.04  ? 320 THR A O   1 
ATOM   7130 C  CB  . THR F 6 306 ? 139.125 95.797  149.542 1.00 91.01  ? 320 THR A CB  1 
ATOM   7131 O  OG1 . THR F 6 306 ? 139.862 96.802  148.836 1.00 91.81  ? 320 THR A OG1 1 
ATOM   7132 C  CG2 . THR F 6 306 ? 139.409 94.446  148.927 1.00 93.82  ? 320 THR A CG2 1 
ATOM   7133 N  N   . ASP F 6 317 ? 149.538 91.059  152.678 1.00 110.79 ? 331 ASP A N   1 
ATOM   7134 C  CA  . ASP F 6 317 ? 148.237 90.486  153.001 1.00 111.04 ? 331 ASP A CA  1 
ATOM   7135 C  C   . ASP F 6 317 ? 147.117 91.438  152.605 1.00 111.71 ? 331 ASP A C   1 
ATOM   7136 O  O   . ASP F 6 317 ? 147.268 92.651  152.710 1.00 111.40 ? 331 ASP A O   1 
ATOM   7137 C  CB  . ASP F 6 317 ? 148.150 90.157  154.492 1.00 107.72 ? 331 ASP A CB  1 
ATOM   7138 N  N   . PRO F 6 318 ? 145.991 90.891  152.141 1.00 105.32 ? 332 PRO A N   1 
ATOM   7139 C  CA  . PRO F 6 318 ? 144.858 91.749  151.762 1.00 102.50 ? 332 PRO A CA  1 
ATOM   7140 C  C   . PRO F 6 318 ? 144.204 92.467  152.934 1.00 104.59 ? 332 PRO A C   1 
ATOM   7141 O  O   . PRO F 6 318 ? 143.449 93.421  152.704 1.00 107.14 ? 332 PRO A O   1 
ATOM   7142 C  CB  . PRO F 6 318 ? 143.885 90.768  151.096 1.00 102.35 ? 332 PRO A CB  1 
ATOM   7143 C  CG  . PRO F 6 318 ? 144.226 89.443  151.675 1.00 102.78 ? 332 PRO A CG  1 
ATOM   7144 C  CD  . PRO F 6 318 ? 145.701 89.461  151.937 1.00 103.36 ? 332 PRO A CD  1 
ATOM   7145 N  N   . ARG F 6 319 ? 144.463 92.045  154.173 1.00 101.93 ? 333 ARG A N   1 
ATOM   7146 C  CA  . ARG F 6 319 ? 143.873 92.705  155.332 1.00 100.41 ? 333 ARG A CA  1 
ATOM   7147 C  C   . ARG F 6 319 ? 144.329 94.152  155.478 1.00 100.56 ? 333 ARG A C   1 
ATOM   7148 O  O   . ARG F 6 319 ? 143.503 95.026  155.772 1.00 100.21 ? 333 ARG A O   1 
ATOM   7149 C  CB  . ARG F 6 319 ? 144.207 91.923  156.603 1.00 94.75  ? 333 ARG A CB  1 
ATOM   7150 N  N   . VAL F 6 320 ? 145.615 94.427  155.283 1.00 90.70  ? 334 VAL A N   1 
ATOM   7151 C  CA  . VAL F 6 320 ? 146.097 95.797  155.397 1.00 93.04  ? 334 VAL A CA  1 
ATOM   7152 C  C   . VAL F 6 320 ? 145.542 96.684  154.285 1.00 91.16  ? 334 VAL A C   1 
ATOM   7153 O  O   . VAL F 6 320 ? 145.227 97.852  154.531 1.00 93.25  ? 334 VAL A O   1 
ATOM   7154 C  CB  . VAL F 6 320 ? 147.637 95.831  155.437 1.00 92.99  ? 334 VAL A CB  1 
ATOM   7155 C  CG1 . VAL F 6 320 ? 148.238 95.301  154.149 1.00 93.51  ? 334 VAL A CG1 1 
ATOM   7156 C  CG2 . VAL F 6 320 ? 148.129 97.240  155.721 1.00 94.23  ? 334 VAL A CG2 1 
ATOM   7157 N  N   . THR F 6 321 ? 145.391 96.152  153.069 1.00 81.68  ? 335 THR A N   1 
ATOM   7158 C  CA  . THR F 6 321 ? 144.753 96.925  152.008 1.00 84.47  ? 335 THR A CA  1 
ATOM   7159 C  C   . THR F 6 321 ? 143.292 97.198  152.335 1.00 87.18  ? 335 THR A C   1 
ATOM   7160 O  O   . THR F 6 321 ? 142.781 98.293  152.067 1.00 89.81  ? 335 THR A O   1 
ATOM   7161 C  CB  . THR F 6 321 ? 144.874 96.202  150.670 1.00 81.95  ? 335 THR A CB  1 
ATOM   7162 O  OG1 . THR F 6 321 ? 143.852 95.207  150.572 1.00 89.78  ? 335 THR A OG1 1 
ATOM   7163 C  CG2 . THR F 6 321 ? 146.229 95.542  150.548 1.00 84.73  ? 335 THR A CG2 1 
ATOM   7164 N  N   . ARG F 6 322 ? 142.602 96.216  152.921 1.00 83.48  ? 336 ARG A N   1 
ATOM   7165 C  CA  . ARG F 6 322 ? 141.224 96.440  153.340 1.00 82.17  ? 336 ARG A CA  1 
ATOM   7166 C  C   . ARG F 6 322 ? 141.140 97.556  154.373 1.00 85.76  ? 336 ARG A C   1 
ATOM   7167 O  O   . ARG F 6 322 ? 140.265 98.424  154.288 1.00 86.69  ? 336 ARG A O   1 
ATOM   7168 C  CB  . ARG F 6 322 ? 140.625 95.147  153.890 1.00 80.62  ? 336 ARG A CB  1 
ATOM   7169 N  N   . ALA F 6 323 ? 142.056 97.562  155.345 1.00 75.55  ? 337 ALA A N   1 
ATOM   7170 C  CA  . ALA F 6 323 ? 142.050 98.621  156.353 1.00 73.25  ? 337 ALA A CA  1 
ATOM   7171 C  C   . ALA F 6 323 ? 142.331 99.989  155.736 1.00 80.32  ? 337 ALA A C   1 
ATOM   7172 O  O   . ALA F 6 323 ? 141.637 100.977 156.042 1.00 80.82  ? 337 ALA A O   1 
ATOM   7173 C  CB  . ALA F 6 323 ? 143.073 98.307  157.442 1.00 71.43  ? 337 ALA A CB  1 
ATOM   7174 N  N   . LYS F 6 324 ? 143.341 100.065 154.865 1.00 76.03  ? 338 LYS A N   1 
ATOM   7175 C  CA  . LYS F 6 324 ? 143.681 101.327 154.217 1.00 73.76  ? 338 LYS A CA  1 
ATOM   7176 C  C   . LYS F 6 324 ? 142.502 101.877 153.431 1.00 75.31  ? 338 LYS A C   1 
ATOM   7177 O  O   . LYS F 6 324 ? 142.178 103.071 153.521 1.00 77.82  ? 338 LYS A O   1 
ATOM   7178 C  CB  . LYS F 6 324 ? 144.871 101.130 153.282 1.00 72.99  ? 338 LYS A CB  1 
ATOM   7179 C  CG  . LYS F 6 324 ? 146.180 100.797 153.953 1.00 75.26  ? 338 LYS A CG  1 
ATOM   7180 C  CD  . LYS F 6 324 ? 147.340 101.096 153.023 1.00 76.33  ? 338 LYS A CD  1 
ATOM   7181 C  CE  . LYS F 6 324 ? 147.041 100.641 151.609 1.00 71.57  ? 338 LYS A CE  1 
ATOM   7182 N  NZ  . LYS F 6 324 ? 148.279 100.504 150.801 1.00 75.37  ? 338 LYS A NZ  1 
ATOM   7183 N  N   . TYR F 6 325 ? 141.847 101.019 152.651 1.00 68.35  ? 339 TYR A N   1 
ATOM   7184 C  CA  . TYR F 6 325 ? 140.745 101.498 151.833 1.00 66.60  ? 339 TYR A CA  1 
ATOM   7185 C  C   . TYR F 6 325 ? 139.515 101.795 152.673 1.00 66.87  ? 339 TYR A C   1 
ATOM   7186 O  O   . TYR F 6 325 ? 138.716 102.654 152.300 1.00 81.18  ? 339 TYR A O   1 
ATOM   7187 C  CB  . TYR F 6 325 ? 140.453 100.499 150.719 1.00 65.69  ? 339 TYR A CB  1 
ATOM   7188 C  CG  . TYR F 6 325 ? 141.407 100.682 149.566 1.00 68.25  ? 339 TYR A CG  1 
ATOM   7189 C  CD1 . TYR F 6 325 ? 141.184 101.655 148.610 1.00 70.77  ? 339 TYR A CD1 1 
ATOM   7190 C  CD2 . TYR F 6 325 ? 142.557 99.918  149.464 1.00 69.24  ? 339 TYR A CD2 1 
ATOM   7191 C  CE1 . TYR F 6 325 ? 142.061 101.845 147.570 1.00 72.38  ? 339 TYR A CE1 1 
ATOM   7192 C  CE2 . TYR F 6 325 ? 143.441 100.101 148.426 1.00 73.71  ? 339 TYR A CE2 1 
ATOM   7193 C  CZ  . TYR F 6 325 ? 143.188 101.068 147.481 1.00 75.98  ? 339 TYR A CZ  1 
ATOM   7194 O  OH  . TYR F 6 325 ? 144.061 101.263 146.439 1.00 74.37  ? 339 TYR A OH  1 
ATOM   7195 N  N   . PHE F 6 326 ? 139.373 101.152 153.834 1.00 61.99  ? 340 PHE A N   1 
ATOM   7196 C  CA  . PHE F 6 326 ? 138.309 101.545 154.751 1.00 67.82  ? 340 PHE A CA  1 
ATOM   7197 C  C   . PHE F 6 326 ? 138.498 102.977 155.233 1.00 74.91  ? 340 PHE A C   1 
ATOM   7198 O  O   . PHE F 6 326 ? 137.552 103.776 155.225 1.00 77.45  ? 340 PHE A O   1 
ATOM   7199 C  CB  . PHE F 6 326 ? 138.262 100.593 155.941 1.00 67.15  ? 340 PHE A CB  1 
ATOM   7200 C  CG  . PHE F 6 326 ? 137.190 100.921 156.928 1.00 66.88  ? 340 PHE A CG  1 
ATOM   7201 C  CD1 . PHE F 6 326 ? 135.872 101.005 156.530 1.00 72.47  ? 340 PHE A CD1 1 
ATOM   7202 C  CD2 . PHE F 6 326 ? 137.500 101.158 158.250 1.00 69.78  ? 340 PHE A CD2 1 
ATOM   7203 C  CE1 . PHE F 6 326 ? 134.883 101.310 157.433 1.00 72.41  ? 340 PHE A CE1 1 
ATOM   7204 C  CE2 . PHE F 6 326 ? 136.514 101.466 159.156 1.00 74.03  ? 340 PHE A CE2 1 
ATOM   7205 C  CZ  . PHE F 6 326 ? 135.202 101.540 158.746 1.00 73.16  ? 340 PHE A CZ  1 
ATOM   7206 N  N   . ILE F 6 327 ? 139.713 103.319 155.664 1.00 66.63  ? 341 ILE A N   1 
ATOM   7207 C  CA  . ILE F 6 327 ? 139.956 104.675 156.157 1.00 56.51  ? 341 ILE A CA  1 
ATOM   7208 C  C   . ILE F 6 327 ? 139.770 105.703 155.044 1.00 54.86  ? 341 ILE A C   1 
ATOM   7209 O  O   . ILE F 6 327 ? 139.128 106.755 155.235 1.00 67.25  ? 341 ILE A O   1 
ATOM   7210 C  CB  . ILE F 6 327 ? 141.355 104.754 156.787 1.00 61.86  ? 341 ILE A CB  1 
ATOM   7211 C  CG1 . ILE F 6 327 ? 141.480 103.730 157.914 1.00 57.09  ? 341 ILE A CG1 1 
ATOM   7212 C  CG2 . ILE F 6 327 ? 141.625 106.147 157.307 1.00 66.62  ? 341 ILE A CG2 1 
ATOM   7213 C  CD1 . ILE F 6 327 ? 142.886 103.525 158.395 1.00 57.89  ? 341 ILE A CD1 1 
ATOM   7214 N  N   . ARG F 6 328 ? 140.319 105.409 153.864 1.00 53.08  ? 342 ARG A N   1 
ATOM   7215 C  CA  . ARG F 6 328 ? 140.135 106.306 152.730 1.00 51.26  ? 342 ARG A CA  1 
ATOM   7216 C  C   . ARG F 6 328 ? 138.657 106.480 152.401 1.00 56.58  ? 342 ARG A C   1 
ATOM   7217 O  O   . ARG F 6 328 ? 138.213 107.585 152.073 1.00 60.90  ? 342 ARG A O   1 
ATOM   7218 C  CB  . ARG F 6 328 ? 140.901 105.776 151.520 1.00 56.29  ? 342 ARG A CB  1 
ATOM   7219 C  CG  . ARG F 6 328 ? 141.293 106.844 150.533 1.00 64.79  ? 342 ARG A CG  1 
ATOM   7220 C  CD  . ARG F 6 328 ? 141.345 106.299 149.125 1.00 62.05  ? 342 ARG A CD  1 
ATOM   7221 N  NE  . ARG F 6 328 ? 140.029 105.884 148.663 1.00 69.24  ? 342 ARG A NE  1 
ATOM   7222 C  CZ  . ARG F 6 328 ? 139.817 105.121 147.602 1.00 72.01  ? 342 ARG A CZ  1 
ATOM   7223 N  NH1 . ARG F 6 328 ? 140.816 104.693 146.850 1.00 70.00  ? 342 ARG A NH1 1 
ATOM   7224 N  NH2 . ARG F 6 328 ? 138.571 104.780 147.288 1.00 69.93  ? 342 ARG A NH2 1 
ATOM   7225 N  N   . ASP F 6 329 ? 137.876 105.399 152.498 1.00 58.50  ? 343 ASP A N   1 
ATOM   7226 C  CA  . ASP F 6 329 ? 136.455 105.476 152.192 1.00 55.06  ? 343 ASP A CA  1 
ATOM   7227 C  C   . ASP F 6 329 ? 135.696 106.287 153.226 1.00 58.68  ? 343 ASP A C   1 
ATOM   7228 O  O   . ASP F 6 329 ? 134.716 106.946 152.881 1.00 65.53  ? 343 ASP A O   1 
ATOM   7229 C  CB  . ASP F 6 329 ? 135.866 104.073 152.083 1.00 56.57  ? 343 ASP A CB  1 
ATOM   7230 N  N   . GLU F 6 330 ? 136.114 106.247 154.493 1.00 60.56  ? 344 GLU A N   1 
ATOM   7231 C  CA  . GLU F 6 330 ? 135.495 107.122 155.490 1.00 54.13  ? 344 GLU A CA  1 
ATOM   7232 C  C   . GLU F 6 330 ? 135.694 108.589 155.133 1.00 60.82  ? 344 GLU A C   1 
ATOM   7233 O  O   . GLU F 6 330 ? 134.735 109.382 155.131 1.00 62.25  ? 344 GLU A O   1 
ATOM   7234 C  CB  . GLU F 6 330 ? 136.071 106.841 156.874 1.00 48.84  ? 344 GLU A CB  1 
ATOM   7235 C  CG  . GLU F 6 330 ? 135.740 105.477 157.419 1.00 61.43  ? 344 GLU A CG  1 
ATOM   7236 C  CD  . GLU F 6 330 ? 134.319 105.387 157.917 1.00 74.66  ? 344 GLU A CD  1 
ATOM   7237 O  OE1 . GLU F 6 330 ? 134.064 105.804 159.064 1.00 77.59  ? 344 GLU A OE1 1 
ATOM   7238 O  OE2 . GLU F 6 330 ? 133.453 104.900 157.161 1.00 77.01  ? 344 GLU A OE2 1 
ATOM   7239 N  N   . PHE F 6 331 ? 136.932 108.968 154.809 1.00 55.02  ? 345 PHE A N   1 
ATOM   7240 C  CA  . PHE F 6 331 ? 137.166 110.364 154.443 1.00 43.40  ? 345 PHE A CA  1 
ATOM   7241 C  C   . PHE F 6 331 ? 136.413 110.753 153.170 1.00 44.39  ? 345 PHE A C   1 
ATOM   7242 O  O   . PHE F 6 331 ? 135.835 111.846 153.097 1.00 49.24  ? 345 PHE A O   1 
ATOM   7243 C  CB  . PHE F 6 331 ? 138.661 110.628 154.298 1.00 47.09  ? 345 PHE A CB  1 
ATOM   7244 C  CG  . PHE F 6 331 ? 139.354 110.865 155.609 1.00 55.21  ? 345 PHE A CG  1 
ATOM   7245 C  CD1 . PHE F 6 331 ? 139.342 112.114 156.195 1.00 48.68  ? 345 PHE A CD1 1 
ATOM   7246 C  CD2 . PHE F 6 331 ? 140.003 109.836 156.261 1.00 47.78  ? 345 PHE A CD2 1 
ATOM   7247 C  CE1 . PHE F 6 331 ? 139.966 112.331 157.392 1.00 38.38  ? 345 PHE A CE1 1 
ATOM   7248 C  CE2 . PHE F 6 331 ? 140.627 110.053 157.462 1.00 43.40  ? 345 PHE A CE2 1 
ATOM   7249 C  CZ  . PHE F 6 331 ? 140.609 111.301 158.025 1.00 42.42  ? 345 PHE A CZ  1 
ATOM   7250 N  N   . LEU F 6 332 ? 136.386 109.869 152.169 1.00 53.81  ? 346 LEU A N   1 
ATOM   7251 C  CA  . LEU F 6 332 ? 135.675 110.171 150.929 1.00 52.60  ? 346 LEU A CA  1 
ATOM   7252 C  C   . LEU F 6 332 ? 134.163 110.205 151.115 1.00 51.14  ? 346 LEU A C   1 
ATOM   7253 O  O   . LEU F 6 332 ? 133.478 110.956 150.415 1.00 49.35  ? 346 LEU A O   1 
ATOM   7254 C  CB  . LEU F 6 332 ? 136.045 109.157 149.851 1.00 47.51  ? 346 LEU A CB  1 
ATOM   7255 C  CG  . LEU F 6 332 ? 137.439 109.294 149.247 1.00 46.50  ? 346 LEU A CG  1 
ATOM   7256 C  CD1 . LEU F 6 332 ? 137.652 108.245 148.181 1.00 56.11  ? 346 LEU A CD1 1 
ATOM   7257 C  CD2 . LEU F 6 332 ? 137.643 110.678 148.677 1.00 50.09  ? 346 LEU A CD2 1 
ATOM   7258 N  N   . ARG F 6 333 ? 133.620 109.398 152.023 1.00 44.72  ? 347 ARG A N   1 
ATOM   7259 C  CA  . ARG F 6 333 ? 132.204 109.463 152.344 1.00 45.66  ? 347 ARG A CA  1 
ATOM   7260 C  C   . ARG F 6 333 ? 131.834 110.766 153.026 1.00 55.32  ? 347 ARG A C   1 
ATOM   7261 O  O   . ARG F 6 333 ? 130.720 111.256 152.826 1.00 58.17  ? 347 ARG A O   1 
ATOM   7262 C  CB  . ARG F 6 333 ? 131.805 108.286 153.234 1.00 41.06  ? 347 ARG A CB  1 
ATOM   7263 N  N   . ILE F 6 334 ? 132.726 111.329 153.838 1.00 63.37  ? 348 ILE A N   1 
ATOM   7264 C  CA  . ILE F 6 334 ? 132.474 112.691 154.305 1.00 56.48  ? 348 ILE A CA  1 
ATOM   7265 C  C   . ILE F 6 334 ? 132.529 113.698 153.155 1.00 48.98  ? 348 ILE A C   1 
ATOM   7266 O  O   . ILE F 6 334 ? 131.636 114.541 153.036 1.00 49.07  ? 348 ILE A O   1 
ATOM   7267 C  CB  . ILE F 6 334 ? 133.440 113.113 155.423 1.00 51.37  ? 348 ILE A CB  1 
ATOM   7268 C  CG1 . ILE F 6 334 ? 133.068 112.457 156.741 1.00 51.89  ? 348 ILE A CG1 1 
ATOM   7269 C  CG2 . ILE F 6 334 ? 133.386 114.608 155.622 1.00 46.81  ? 348 ILE A CG2 1 
ATOM   7270 C  CD1 . ILE F 6 334 ? 134.228 112.351 157.675 1.00 52.37  ? 348 ILE A CD1 1 
ATOM   7271 N  N   . SER F 6 335 ? 133.551 113.625 152.295 1.00 43.57  ? 349 SER A N   1 
ATOM   7272 C  CA  . SER F 6 335 ? 133.748 114.686 151.307 1.00 42.67  ? 349 SER A CA  1 
ATOM   7273 C  C   . SER F 6 335 ? 132.644 114.700 150.256 1.00 55.87  ? 349 SER A C   1 
ATOM   7274 O  O   . SER F 6 335 ? 132.087 115.759 149.949 1.00 62.98  ? 349 SER A O   1 
ATOM   7275 C  CB  . SER F 6 335 ? 135.111 114.543 150.639 1.00 50.41  ? 349 SER A CB  1 
ATOM   7276 O  OG  . SER F 6 335 ? 135.076 113.560 149.628 1.00 55.62  ? 349 SER A OG  1 
ATOM   7277 N  N   . THR F 6 336 ? 132.317 113.541 149.683 1.00 65.17  ? 350 THR A N   1 
ATOM   7278 C  CA  . THR F 6 336 ? 131.349 113.467 148.585 1.00 60.21  ? 350 THR A CA  1 
ATOM   7279 C  C   . THR F 6 336 ? 129.912 113.404 149.106 1.00 63.91  ? 350 THR A C   1 
ATOM   7280 O  O   . THR F 6 336 ? 129.134 112.517 148.762 1.00 65.56  ? 350 THR A O   1 
ATOM   7281 C  CB  . THR F 6 336 ? 131.632 112.263 147.698 1.00 57.26  ? 350 THR A CB  1 
ATOM   7282 O  OG1 . THR F 6 336 ? 131.119 111.085 148.327 1.00 53.07  ? 350 THR A OG1 1 
ATOM   7283 C  CG2 . THR F 6 336 ? 133.116 112.097 147.454 1.00 60.09  ? 350 THR A CG2 1 
ATOM   7284 N  N   . ALA F 6 337 ? 129.564 114.365 149.957 1.00 61.95  ? 351 ALA A N   1 
ATOM   7285 C  CA  . ALA F 6 337 ? 128.193 114.433 150.445 1.00 57.53  ? 351 ALA A CA  1 
ATOM   7286 C  C   . ALA F 6 337 ? 127.649 115.854 150.411 1.00 70.28  ? 351 ALA A C   1 
ATOM   7287 O  O   . ALA F 6 337 ? 126.432 116.052 150.341 1.00 73.76  ? 351 ALA A O   1 
ATOM   7288 C  CB  . ALA F 6 337 ? 128.106 113.870 151.862 1.00 50.27  ? 351 ALA A CB  1 
ATOM   7289 N  N   . SER F 6 338 ? 128.531 116.850 150.467 1.00 74.61  ? 352 SER A N   1 
ATOM   7290 C  CA  . SER F 6 338 ? 128.087 118.238 150.502 1.00 71.90  ? 352 SER A CA  1 
ATOM   7291 C  C   . SER F 6 338 ? 128.977 119.145 149.665 1.00 71.57  ? 352 SER A C   1 
ATOM   7292 O  O   . SER F 6 338 ? 129.305 120.256 150.090 1.00 80.90  ? 352 SER A O   1 
ATOM   7293 C  CB  . SER F 6 338 ? 128.041 118.738 151.945 1.00 64.48  ? 352 SER A CB  1 
ATOM   7294 O  OG  . SER F 6 338 ? 126.810 118.399 152.557 1.00 67.59  ? 352 SER A OG  1 
ATOM   7295 N  N   . GLY F 6 339 ? 129.366 118.697 148.476 1.00 65.43  ? 353 GLY A N   1 
ATOM   7296 C  CA  . GLY F 6 339 ? 130.325 119.444 147.688 1.00 67.61  ? 353 GLY A CA  1 
ATOM   7297 C  C   . GLY F 6 339 ? 129.734 120.510 146.790 1.00 76.06  ? 353 GLY A C   1 
ATOM   7298 O  O   . GLY F 6 339 ? 130.278 121.614 146.698 1.00 71.10  ? 353 GLY A O   1 
ATOM   7299 N  N   . ASP F 6 340 ? 128.634 120.175 146.108 1.00 79.87  ? 354 ASP A N   1 
ATOM   7300 C  CA  . ASP F 6 340 ? 127.990 121.019 145.102 1.00 71.54  ? 354 ASP A CA  1 
ATOM   7301 C  C   . ASP F 6 340 ? 128.866 121.189 143.866 1.00 67.71  ? 354 ASP A C   1 
ATOM   7302 O  O   . ASP F 6 340 ? 128.469 121.860 142.910 1.00 68.82  ? 354 ASP A O   1 
ATOM   7303 C  CB  . ASP F 6 340 ? 127.615 122.389 145.678 1.00 69.08  ? 354 ASP A CB  1 
ATOM   7304 N  N   . GLY F 6 341 ? 130.052 120.584 143.870 1.00 63.04  ? 355 GLY A N   1 
ATOM   7305 C  CA  . GLY F 6 341 ? 130.907 120.575 142.701 1.00 61.23  ? 355 GLY A CA  1 
ATOM   7306 C  C   . GLY F 6 341 ? 132.001 121.623 142.677 1.00 65.19  ? 355 GLY A C   1 
ATOM   7307 O  O   . GLY F 6 341 ? 132.660 121.798 141.652 1.00 69.26  ? 355 GLY A O   1 
ATOM   7308 N  N   . ARG F 6 342 ? 132.214 122.325 143.788 1.00 62.52  ? 356 ARG A N   1 
ATOM   7309 C  CA  . ARG F 6 342 ? 133.202 123.392 143.839 1.00 59.11  ? 356 ARG A CA  1 
ATOM   7310 C  C   . ARG F 6 342 ? 134.513 122.982 144.496 1.00 62.88  ? 356 ARG A C   1 
ATOM   7311 O  O   . ARG F 6 342 ? 135.485 123.737 144.419 1.00 70.72  ? 356 ARG A O   1 
ATOM   7312 C  CB  . ARG F 6 342 ? 132.630 124.607 144.567 1.00 61.08  ? 356 ARG A CB  1 
ATOM   7313 C  CG  . ARG F 6 342 ? 131.517 125.304 143.824 1.00 59.20  ? 356 ARG A CG  1 
ATOM   7314 C  CD  . ARG F 6 342 ? 130.906 126.375 144.689 1.00 67.03  ? 356 ARG A CD  1 
ATOM   7315 N  NE  . ARG F 6 342 ? 130.273 125.794 145.866 1.00 72.42  ? 356 ARG A NE  1 
ATOM   7316 C  CZ  . ARG F 6 342 ? 129.654 126.492 146.807 1.00 74.72  ? 356 ARG A CZ  1 
ATOM   7317 N  NH1 . ARG F 6 342 ? 129.566 127.810 146.745 1.00 74.91  ? 356 ARG A NH1 1 
ATOM   7318 N  NH2 . ARG F 6 342 ? 129.107 125.850 147.835 1.00 62.11  ? 356 ARG A NH2 1 
ATOM   7319 N  N   . HIS F 6 343 ? 134.571 121.822 145.146 1.00 43.29  ? 357 HIS A N   1 
ATOM   7320 C  CA  . HIS F 6 343 ? 135.828 121.339 145.691 1.00 41.06  ? 357 HIS A CA  1 
ATOM   7321 C  C   . HIS F 6 343 ? 135.787 119.824 145.795 1.00 45.22  ? 357 HIS A C   1 
ATOM   7322 O  O   . HIS F 6 343 ? 134.719 119.218 145.890 1.00 55.42  ? 357 HIS A O   1 
ATOM   7323 C  CB  . HIS F 6 343 ? 136.161 121.974 147.051 1.00 47.49  ? 357 HIS A CB  1 
ATOM   7324 C  CG  . HIS F 6 343 ? 135.151 121.723 148.131 1.00 44.25  ? 357 HIS A CG  1 
ATOM   7325 N  ND1 . HIS F 6 343 ? 133.932 122.359 148.191 1.00 56.77  ? 357 HIS A ND1 1 
ATOM   7326 C  CD2 . HIS F 6 343 ? 135.192 120.893 149.198 1.00 36.41  ? 357 HIS A CD2 1 
ATOM   7327 C  CE1 . HIS F 6 343 ? 133.267 121.935 149.249 1.00 48.68  ? 357 HIS A CE1 1 
ATOM   7328 N  NE2 . HIS F 6 343 ? 134.010 121.045 149.877 1.00 41.08  ? 357 HIS A NE2 1 
ATOM   7329 N  N   . TYR F 6 344 ? 136.972 119.218 145.766 1.00 43.71  ? 358 TYR A N   1 
ATOM   7330 C  CA  . TYR F 6 344 ? 137.107 117.770 145.795 1.00 43.34  ? 358 TYR A CA  1 
ATOM   7331 C  C   . TYR F 6 344 ? 138.195 117.392 146.788 1.00 49.60  ? 358 TYR A C   1 
ATOM   7332 O  O   . TYR F 6 344 ? 138.871 118.251 147.354 1.00 62.38  ? 358 TYR A O   1 
ATOM   7333 C  CB  . TYR F 6 344 ? 137.427 117.200 144.408 1.00 53.07  ? 358 TYR A CB  1 
ATOM   7334 C  CG  . TYR F 6 344 ? 136.476 117.641 143.320 1.00 58.38  ? 358 TYR A CG  1 
ATOM   7335 C  CD1 . TYR F 6 344 ? 136.666 118.838 142.651 1.00 61.85  ? 358 TYR A CD1 1 
ATOM   7336 C  CD2 . TYR F 6 344 ? 135.397 116.854 142.953 1.00 45.81  ? 358 TYR A CD2 1 
ATOM   7337 C  CE1 . TYR F 6 344 ? 135.804 119.246 141.663 1.00 53.76  ? 358 TYR A CE1 1 
ATOM   7338 C  CE2 . TYR F 6 344 ? 134.529 117.256 141.966 1.00 45.72  ? 358 TYR A CE2 1 
ATOM   7339 C  CZ  . TYR F 6 344 ? 134.741 118.450 141.324 1.00 54.69  ? 358 TYR A CZ  1 
ATOM   7340 O  OH  . TYR F 6 344 ? 133.883 118.857 140.336 1.00 63.06  ? 358 TYR A OH  1 
ATOM   7341 N  N   . CYS F 6 345 ? 138.356 116.089 146.992 1.00 53.08  ? 359 CYS A N   1 
ATOM   7342 C  CA  . CYS F 6 345 ? 139.349 115.538 147.902 1.00 43.70  ? 359 CYS A CA  1 
ATOM   7343 C  C   . CYS F 6 345 ? 140.252 114.577 147.143 1.00 52.50  ? 359 CYS A C   1 
ATOM   7344 O  O   . CYS F 6 345 ? 139.773 113.763 146.349 1.00 58.75  ? 359 CYS A O   1 
ATOM   7345 C  CB  . CYS F 6 345 ? 138.676 114.820 149.072 1.00 40.77  ? 359 CYS A CB  1 
ATOM   7346 S  SG  . CYS F 6 345 ? 139.759 114.428 150.452 1.00 70.50  ? 359 CYS A SG  1 
ATOM   7347 N  N   . TYR F 6 346 ? 141.558 114.670 147.392 1.00 42.53  ? 360 TYR A N   1 
ATOM   7348 C  CA  . TYR F 6 346 ? 142.566 113.889 146.675 1.00 48.34  ? 360 TYR A CA  1 
ATOM   7349 C  C   . TYR F 6 346 ? 143.404 113.109 147.677 1.00 46.93  ? 360 TYR A C   1 
ATOM   7350 O  O   . TYR F 6 346 ? 144.457 113.584 148.116 1.00 54.14  ? 360 TYR A O   1 
ATOM   7351 C  CB  . TYR F 6 346 ? 143.461 114.789 145.825 1.00 34.77  ? 360 TYR A CB  1 
ATOM   7352 C  CG  . TYR F 6 346 ? 142.722 115.705 144.882 1.00 35.57  ? 360 TYR A CG  1 
ATOM   7353 C  CD1 . TYR F 6 346 ? 142.380 115.291 143.607 1.00 47.58  ? 360 TYR A CD1 1 
ATOM   7354 C  CD2 . TYR F 6 346 ? 142.376 116.985 145.263 1.00 42.58  ? 360 TYR A CD2 1 
ATOM   7355 C  CE1 . TYR F 6 346 ? 141.708 116.123 142.747 1.00 49.22  ? 360 TYR A CE1 1 
ATOM   7356 C  CE2 . TYR F 6 346 ? 141.706 117.821 144.408 1.00 50.51  ? 360 TYR A CE2 1 
ATOM   7357 C  CZ  . TYR F 6 346 ? 141.373 117.386 143.153 1.00 53.65  ? 360 TYR A CZ  1 
ATOM   7358 O  OH  . TYR F 6 346 ? 140.701 118.225 142.302 1.00 56.33  ? 360 TYR A OH  1 
ATOM   7359 N  N   . PRO F 6 347 ? 142.984 111.900 148.045 1.00 50.39  ? 361 PRO A N   1 
ATOM   7360 C  CA  . PRO F 6 347 ? 143.706 111.141 149.073 1.00 50.96  ? 361 PRO A CA  1 
ATOM   7361 C  C   . PRO F 6 347 ? 144.890 110.353 148.535 1.00 54.32  ? 361 PRO A C   1 
ATOM   7362 O  O   . PRO F 6 347 ? 144.871 109.826 147.421 1.00 63.75  ? 361 PRO A O   1 
ATOM   7363 C  CB  . PRO F 6 347 ? 142.623 110.197 149.607 1.00 49.69  ? 361 PRO A CB  1 
ATOM   7364 C  CG  . PRO F 6 347 ? 141.745 109.973 148.455 1.00 53.15  ? 361 PRO A CG  1 
ATOM   7365 C  CD  . PRO F 6 347 ? 141.750 111.221 147.628 1.00 50.85  ? 361 PRO A CD  1 
ATOM   7366 N  N   . HIS F 6 348 ? 145.938 110.268 149.355 1.00 49.97  ? 362 HIS A N   1 
ATOM   7367 C  CA  . HIS F 6 348 ? 147.154 109.539 149.023 1.00 55.49  ? 362 HIS A CA  1 
ATOM   7368 C  C   . HIS F 6 348 ? 147.642 108.770 150.242 1.00 56.20  ? 362 HIS A C   1 
ATOM   7369 O  O   . HIS F 6 348 ? 147.309 109.099 151.380 1.00 63.67  ? 362 HIS A O   1 
ATOM   7370 C  CB  . HIS F 6 348 ? 148.273 110.472 148.539 1.00 55.40  ? 362 HIS A CB  1 
ATOM   7371 C  CG  . HIS F 6 348 ? 147.865 111.394 147.435 1.00 59.79  ? 362 HIS A CG  1 
ATOM   7372 N  ND1 . HIS F 6 348 ? 147.690 110.969 146.137 1.00 64.68  ? 362 HIS A ND1 1 
ATOM   7373 C  CD2 . HIS F 6 348 ? 147.615 112.724 147.433 1.00 54.92  ? 362 HIS A CD2 1 
ATOM   7374 C  CE1 . HIS F 6 348 ? 147.338 111.995 145.384 1.00 60.21  ? 362 HIS A CE1 1 
ATOM   7375 N  NE2 . HIS F 6 348 ? 147.288 113.072 146.146 1.00 58.05  ? 362 HIS A NE2 1 
ATOM   7376 N  N   . PHE F 6 349 ? 148.444 107.737 149.992 1.00 61.81  ? 363 PHE A N   1 
ATOM   7377 C  CA  . PHE F 6 349 ? 149.090 106.955 151.041 1.00 63.01  ? 363 PHE A CA  1 
ATOM   7378 C  C   . PHE F 6 349 ? 150.579 107.276 151.042 1.00 65.46  ? 363 PHE A C   1 
ATOM   7379 O  O   . PHE F 6 349 ? 151.249 107.109 150.018 1.00 73.40  ? 363 PHE A O   1 
ATOM   7380 C  CB  . PHE F 6 349 ? 148.880 105.456 150.829 1.00 66.22  ? 363 PHE A CB  1 
ATOM   7381 C  CG  . PHE F 6 349 ? 147.443 105.047 150.696 1.00 67.29  ? 363 PHE A CG  1 
ATOM   7382 C  CD1 . PHE F 6 349 ? 146.563 105.192 151.751 1.00 67.76  ? 363 PHE A CD1 1 
ATOM   7383 C  CD2 . PHE F 6 349 ? 146.979 104.485 149.523 1.00 69.57  ? 363 PHE A CD2 1 
ATOM   7384 C  CE1 . PHE F 6 349 ? 145.246 104.804 151.628 1.00 65.94  ? 363 PHE A CE1 1 
ATOM   7385 C  CE2 . PHE F 6 349 ? 145.662 104.097 149.398 1.00 69.85  ? 363 PHE A CE2 1 
ATOM   7386 C  CZ  . PHE F 6 349 ? 144.798 104.257 150.450 1.00 64.68  ? 363 PHE A CZ  1 
ATOM   7387 N  N   . THR F 6 350 ? 151.099 107.721 152.185 1.00 64.73  ? 364 THR A N   1 
ATOM   7388 C  CA  . THR F 6 350 ? 152.492 108.141 152.309 1.00 71.35  ? 364 THR A CA  1 
ATOM   7389 C  C   . THR F 6 350 ? 153.120 107.487 153.530 1.00 75.33  ? 364 THR A C   1 
ATOM   7390 O  O   . THR F 6 350 ? 152.656 107.699 154.653 1.00 78.33  ? 364 THR A O   1 
ATOM   7391 C  CB  . THR F 6 350 ? 152.600 109.663 152.427 1.00 78.36  ? 364 THR A CB  1 
ATOM   7392 O  OG1 . THR F 6 350 ? 152.021 110.088 153.665 1.00 75.76  ? 364 THR A OG1 1 
ATOM   7393 C  CG2 . THR F 6 350 ? 151.877 110.342 151.288 1.00 72.89  ? 364 THR A CG2 1 
ATOM   7394 N  N   . CYS F 6 351 ? 154.173 106.696 153.314 1.00 100.10 ? 365 CYS A N   1 
ATOM   7395 C  CA  . CYS F 6 351 ? 154.895 106.092 154.430 1.00 100.86 ? 365 CYS A CA  1 
ATOM   7396 C  C   . CYS F 6 351 ? 156.410 106.101 154.296 1.00 104.16 ? 365 CYS A C   1 
ATOM   7397 O  O   . CYS F 6 351 ? 157.090 105.906 155.307 1.00 105.11 ? 365 CYS A O   1 
ATOM   7398 C  CB  . CYS F 6 351 ? 154.440 104.642 154.632 1.00 100.04 ? 365 CYS A CB  1 
ATOM   7399 S  SG  . CYS F 6 351 ? 154.803 103.981 156.272 1.00 113.65 ? 365 CYS A SG  1 
ATOM   7400 N  N   . ALA F 6 352 ? 156.964 106.325 153.111 1.00 123.89 ? 366 ALA A N   1 
ATOM   7401 C  CA  . ALA F 6 352 ? 158.399 106.199 152.884 1.00 124.05 ? 366 ALA A CA  1 
ATOM   7402 C  C   . ALA F 6 352 ? 159.120 107.460 153.354 1.00 124.15 ? 366 ALA A C   1 
ATOM   7403 O  O   . ALA F 6 352 ? 158.586 108.276 154.112 1.00 123.66 ? 366 ALA A O   1 
ATOM   7404 C  CB  . ALA F 6 352 ? 158.676 105.902 151.413 1.00 121.59 ? 366 ALA A CB  1 
ATOM   7405 N  N   . VAL F 6 353 ? 160.367 107.622 152.912 1.00 125.12 ? 367 VAL A N   1 
ATOM   7406 C  CA  . VAL F 6 353 ? 161.163 108.811 153.201 1.00 124.76 ? 367 VAL A CA  1 
ATOM   7407 C  C   . VAL F 6 353 ? 160.593 110.014 152.458 1.00 126.19 ? 367 VAL A C   1 
ATOM   7408 O  O   . VAL F 6 353 ? 161.157 111.112 152.516 1.00 125.77 ? 367 VAL A O   1 
ATOM   7409 C  CB  . VAL F 6 353 ? 162.642 108.591 152.836 1.00 123.47 ? 367 VAL A CB  1 
ATOM   7410 N  N   . ASP F 6 354 ? 159.489 109.802 151.732 1.00 117.71 ? 368 ASP A N   1 
ATOM   7411 C  CA  . ASP F 6 354 ? 158.747 110.868 151.053 1.00 116.82 ? 368 ASP A CA  1 
ATOM   7412 C  C   . ASP F 6 354 ? 159.560 111.462 149.903 1.00 118.98 ? 368 ASP A C   1 
ATOM   7413 O  O   . ASP F 6 354 ? 159.658 112.681 149.747 1.00 120.28 ? 368 ASP A O   1 
ATOM   7414 C  CB  . ASP F 6 354 ? 158.307 111.957 152.036 1.00 115.29 ? 368 ASP A CB  1 
ATOM   7415 N  N   . THR F 6 355 ? 160.145 110.582 149.089 1.00 107.01 ? 369 THR A N   1 
ATOM   7416 C  CA  . THR F 6 355 ? 160.903 111.043 147.932 1.00 105.83 ? 369 THR A CA  1 
ATOM   7417 C  C   . THR F 6 355 ? 159.977 111.556 146.836 1.00 106.52 ? 369 THR A C   1 
ATOM   7418 O  O   . THR F 6 355 ? 160.394 112.335 145.971 1.00 106.59 ? 369 THR A O   1 
ATOM   7419 C  CB  . THR F 6 355 ? 161.787 109.914 147.402 1.00 105.95 ? 369 THR A CB  1 
ATOM   7420 N  N   . GLU F 6 356 ? 158.712 111.133 146.855 1.00 95.55  ? 370 GLU A N   1 
ATOM   7421 C  CA  . GLU F 6 356 ? 157.758 111.469 145.806 1.00 93.73  ? 370 GLU A CA  1 
ATOM   7422 C  C   . GLU F 6 356 ? 156.533 112.205 146.337 1.00 92.91  ? 370 GLU A C   1 
ATOM   7423 O  O   . GLU F 6 356 ? 155.458 112.122 145.737 1.00 91.05  ? 370 GLU A O   1 
ATOM   7424 C  CB  . GLU F 6 356 ? 157.327 110.207 145.061 1.00 88.47  ? 370 GLU A CB  1 
ATOM   7425 N  N   . ASN F 6 357 ? 156.667 112.922 147.453 1.00 86.55  ? 371 ASN A N   1 
ATOM   7426 C  CA  . ASN F 6 357 ? 155.530 113.638 148.016 1.00 79.17  ? 371 ASN A CA  1 
ATOM   7427 C  C   . ASN F 6 357 ? 155.380 115.048 147.470 1.00 79.95  ? 371 ASN A C   1 
ATOM   7428 O  O   . ASN F 6 357 ? 154.370 115.696 147.757 1.00 83.08  ? 371 ASN A O   1 
ATOM   7429 C  CB  . ASN F 6 357 ? 155.641 113.706 149.539 1.00 75.09  ? 371 ASN A CB  1 
ATOM   7430 C  CG  . ASN F 6 357 ? 155.001 112.522 150.220 1.00 79.99  ? 371 ASN A CG  1 
ATOM   7431 O  OD1 . ASN F 6 357 ? 154.369 111.689 149.577 1.00 82.90  ? 371 ASN A OD1 1 
ATOM   7432 N  ND2 . ASN F 6 357 ? 155.154 112.445 151.533 1.00 84.27  ? 371 ASN A ND2 1 
ATOM   7433 N  N   . ILE F 6 358 ? 156.343 115.540 146.701 1.00 73.23  ? 372 ILE A N   1 
ATOM   7434 C  CA  . ILE F 6 358 ? 156.280 116.885 146.148 1.00 70.82  ? 372 ILE A CA  1 
ATOM   7435 C  C   . ILE F 6 358 ? 155.666 116.891 144.755 1.00 71.77  ? 372 ILE A C   1 
ATOM   7436 O  O   . ILE F 6 358 ? 154.995 117.849 144.376 1.00 75.37  ? 372 ILE A O   1 
ATOM   7437 C  CB  . ILE F 6 358 ? 157.680 117.531 146.143 1.00 71.12  ? 372 ILE A CB  1 
ATOM   7438 C  CG1 . ILE F 6 358 ? 158.378 117.294 147.484 1.00 78.10  ? 372 ILE A CG1 1 
ATOM   7439 C  CG2 . ILE F 6 358 ? 157.569 119.013 145.888 1.00 64.74  ? 372 ILE A CG2 1 
ATOM   7440 C  CD1 . ILE F 6 358 ? 159.553 116.343 147.415 1.00 75.54  ? 372 ILE A CD1 1 
ATOM   7441 N  N   . ARG F 6 359 ? 155.886 115.829 143.976 1.00 70.52  ? 373 ARG A N   1 
ATOM   7442 C  CA  . ARG F 6 359 ? 155.232 115.725 142.678 1.00 67.14  ? 373 ARG A CA  1 
ATOM   7443 C  C   . ARG F 6 359 ? 153.737 115.496 142.826 1.00 66.17  ? 373 ARG A C   1 
ATOM   7444 O  O   . ARG F 6 359 ? 152.956 115.925 141.972 1.00 71.68  ? 373 ARG A O   1 
ATOM   7445 C  CB  . ARG F 6 359 ? 155.856 114.600 141.855 1.00 68.80  ? 373 ARG A CB  1 
ATOM   7446 C  CG  . ARG F 6 359 ? 157.343 114.761 141.607 1.00 75.12  ? 373 ARG A CG  1 
ATOM   7447 C  CD  . ARG F 6 359 ? 157.636 115.889 140.629 1.00 71.23  ? 373 ARG A CD  1 
ATOM   7448 N  NE  . ARG F 6 359 ? 156.563 116.068 139.660 1.00 78.83  ? 373 ARG A NE  1 
ATOM   7449 C  CZ  . ARG F 6 359 ? 156.705 116.674 138.489 1.00 76.38  ? 373 ARG A CZ  1 
ATOM   7450 N  NH1 . ARG F 6 359 ? 157.871 117.159 138.098 1.00 68.76  ? 373 ARG A NH1 1 
ATOM   7451 N  NH2 . ARG F 6 359 ? 155.649 116.794 137.690 1.00 69.18  ? 373 ARG A NH2 1 
ATOM   7452 N  N   . ARG F 6 360 ? 153.319 114.814 143.892 1.00 69.03  ? 374 ARG A N   1 
ATOM   7453 C  CA  . ARG F 6 360 ? 151.900 114.574 144.106 1.00 65.61  ? 374 ARG A CA  1 
ATOM   7454 C  C   . ARG F 6 360 ? 151.134 115.868 144.328 1.00 67.89  ? 374 ARG A C   1 
ATOM   7455 O  O   . ARG F 6 360 ? 150.084 116.066 143.711 1.00 74.76  ? 374 ARG A O   1 
ATOM   7456 C  CB  . ARG F 6 360 ? 151.706 113.627 145.288 1.00 68.76  ? 374 ARG A CB  1 
ATOM   7457 C  CG  . ARG F 6 360 ? 152.009 112.185 144.948 1.00 68.94  ? 374 ARG A CG  1 
ATOM   7458 C  CD  . ARG F 6 360 ? 151.452 111.228 145.981 1.00 69.72  ? 374 ARG A CD  1 
ATOM   7459 N  NE  . ARG F 6 360 ? 152.448 110.862 146.978 1.00 75.93  ? 374 ARG A NE  1 
ATOM   7460 C  CZ  . ARG F 6 360 ? 152.593 109.643 147.476 1.00 74.52  ? 374 ARG A CZ  1 
ATOM   7461 N  NH1 . ARG F 6 360 ? 151.828 108.640 147.082 1.00 71.70  ? 374 ARG A NH1 1 
ATOM   7462 N  NH2 . ARG F 6 360 ? 153.534 109.423 148.390 1.00 72.06  ? 374 ARG A NH2 1 
ATOM   7463 N  N   . VAL F 6 361 ? 151.652 116.759 145.173 1.00 59.24  ? 375 VAL A N   1 
ATOM   7464 C  CA  . VAL F 6 361 ? 151.010 118.052 145.385 1.00 61.40  ? 375 VAL A CA  1 
ATOM   7465 C  C   . VAL F 6 361 ? 150.959 118.842 144.084 1.00 67.10  ? 375 VAL A C   1 
ATOM   7466 O  O   . VAL F 6 361 ? 149.965 119.514 143.791 1.00 66.85  ? 375 VAL A O   1 
ATOM   7467 C  CB  . VAL F 6 361 ? 151.741 118.830 146.492 1.00 56.74  ? 375 VAL A CB  1 
ATOM   7468 C  CG1 . VAL F 6 361 ? 151.081 120.174 146.718 1.00 57.73  ? 375 VAL A CG1 1 
ATOM   7469 C  CG2 . VAL F 6 361 ? 151.765 118.020 147.770 1.00 57.90  ? 375 VAL A CG2 1 
ATOM   7470 N  N   . PHE F 6 362 ? 152.027 118.772 143.287 1.00 62.19  ? 376 PHE A N   1 
ATOM   7471 C  CA  . PHE F 6 362 ? 152.036 119.403 141.970 1.00 51.52  ? 376 PHE A CA  1 
ATOM   7472 C  C   . PHE F 6 362 ? 150.886 118.890 141.113 1.00 57.68  ? 376 PHE A C   1 
ATOM   7473 O  O   . PHE F 6 362 ? 150.128 119.673 140.523 1.00 62.98  ? 376 PHE A O   1 
ATOM   7474 C  CB  . PHE F 6 362 ? 153.382 119.131 141.295 1.00 57.00  ? 376 PHE A CB  1 
ATOM   7475 C  CG  . PHE F 6 362 ? 153.591 119.876 140.009 1.00 66.81  ? 376 PHE A CG  1 
ATOM   7476 C  CD1 . PHE F 6 362 ? 153.060 119.408 138.821 1.00 65.47  ? 376 PHE A CD1 1 
ATOM   7477 C  CD2 . PHE F 6 362 ? 154.340 121.033 139.983 1.00 65.14  ? 376 PHE A CD2 1 
ATOM   7478 C  CE1 . PHE F 6 362 ? 153.254 120.091 137.647 1.00 60.63  ? 376 PHE A CE1 1 
ATOM   7479 C  CE2 . PHE F 6 362 ? 154.537 121.713 138.807 1.00 63.32  ? 376 PHE A CE2 1 
ATOM   7480 C  CZ  . PHE F 6 362 ? 153.993 121.242 137.640 1.00 58.94  ? 376 PHE A CZ  1 
ATOM   7481 N  N   . ASN F 6 363 ? 150.737 117.568 141.040 1.00 61.37  ? 377 ASN A N   1 
ATOM   7482 C  CA  . ASN F 6 363 ? 149.710 116.980 140.193 1.00 61.32  ? 377 ASN A CA  1 
ATOM   7483 C  C   . ASN F 6 363 ? 148.308 117.341 140.660 1.00 62.67  ? 377 ASN A C   1 
ATOM   7484 O  O   . ASN F 6 363 ? 147.446 117.626 139.825 1.00 67.65  ? 377 ASN A O   1 
ATOM   7485 C  CB  . ASN F 6 363 ? 149.877 115.466 140.135 1.00 59.94  ? 377 ASN A CB  1 
ATOM   7486 C  CG  . ASN F 6 363 ? 151.111 115.050 139.371 1.00 65.05  ? 377 ASN A CG  1 
ATOM   7487 O  OD1 . ASN F 6 363 ? 151.521 115.720 138.428 1.00 65.75  ? 377 ASN A OD1 1 
ATOM   7488 N  ND2 . ASN F 6 363 ? 151.709 113.940 139.772 1.00 65.92  ? 377 ASN A ND2 1 
ATOM   7489 N  N   . ASP F 6 364 ? 148.046 117.333 141.971 1.00 52.80  ? 378 ASP A N   1 
ATOM   7490 C  CA  . ASP F 6 364 ? 146.693 117.682 142.408 1.00 47.29  ? 378 ASP A CA  1 
ATOM   7491 C  C   . ASP F 6 364 ? 146.420 119.176 142.304 1.00 54.67  ? 378 ASP A C   1 
ATOM   7492 O  O   . ASP F 6 364 ? 145.278 119.571 142.059 1.00 62.82  ? 378 ASP A O   1 
ATOM   7493 C  CB  . ASP F 6 364 ? 146.398 117.199 143.827 1.00 59.27  ? 378 ASP A CB  1 
ATOM   7494 C  CG  . ASP F 6 364 ? 147.035 115.871 144.144 1.00 71.49  ? 378 ASP A CG  1 
ATOM   7495 O  OD1 . ASP F 6 364 ? 146.522 114.834 143.678 1.00 75.76  ? 378 ASP A OD1 1 
ATOM   7496 O  OD2 . ASP F 6 364 ? 148.048 115.855 144.858 1.00 70.22  ? 378 ASP A OD2 1 
ATOM   7497 N  N   . CYS F 6 365 ? 147.436 120.027 142.470 1.00 56.77  ? 379 CYS A N   1 
ATOM   7498 C  CA  . CYS F 6 365 ? 147.228 121.450 142.239 1.00 48.22  ? 379 CYS A CA  1 
ATOM   7499 C  C   . CYS F 6 365 ? 146.993 121.767 140.772 1.00 55.91  ? 379 CYS A C   1 
ATOM   7500 O  O   . CYS F 6 365 ? 146.334 122.763 140.468 1.00 61.59  ? 379 CYS A O   1 
ATOM   7501 C  CB  . CYS F 6 365 ? 148.418 122.258 142.754 1.00 45.39  ? 379 CYS A CB  1 
ATOM   7502 S  SG  . CYS F 6 365 ? 148.495 122.383 144.543 1.00 69.28  ? 379 CYS A SG  1 
ATOM   7503 N  N   . ARG F 6 366 ? 147.523 120.956 139.855 1.00 59.48  ? 380 ARG A N   1 
ATOM   7504 C  CA  . ARG F 6 366 ? 147.184 121.138 138.447 1.00 52.67  ? 380 ARG A CA  1 
ATOM   7505 C  C   . ARG F 6 366 ? 145.742 120.730 138.172 1.00 49.25  ? 380 ARG A C   1 
ATOM   7506 O  O   . ARG F 6 366 ? 145.013 121.432 137.460 1.00 59.15  ? 380 ARG A O   1 
ATOM   7507 C  CB  . ARG F 6 366 ? 148.147 120.346 137.568 1.00 54.45  ? 380 ARG A CB  1 
ATOM   7508 C  CG  . ARG F 6 366 ? 147.645 120.137 136.167 1.00 48.86  ? 380 ARG A CG  1 
ATOM   7509 C  CD  . ARG F 6 366 ? 148.775 120.050 135.162 1.00 54.97  ? 380 ARG A CD  1 
ATOM   7510 N  NE  . ARG F 6 366 ? 149.797 119.082 135.536 1.00 63.65  ? 380 ARG A NE  1 
ATOM   7511 C  CZ  . ARG F 6 366 ? 149.613 117.770 135.598 1.00 66.63  ? 380 ARG A CZ  1 
ATOM   7512 N  NH1 . ARG F 6 366 ? 148.437 117.222 135.346 1.00 62.07  ? 380 ARG A NH1 1 
ATOM   7513 N  NH2 . ARG F 6 366 ? 150.636 116.987 135.923 1.00 62.81  ? 380 ARG A NH2 1 
ATOM   7514 N  N   . ASP F 6 367 ? 145.310 119.598 138.737 1.00 54.19  ? 381 ASP A N   1 
ATOM   7515 C  CA  . ASP F 6 367 ? 143.938 119.131 138.558 1.00 42.18  ? 381 ASP A CA  1 
ATOM   7516 C  C   . ASP F 6 367 ? 142.928 120.099 139.149 1.00 41.23  ? 381 ASP A C   1 
ATOM   7517 O  O   . ASP F 6 367 ? 141.847 120.280 138.586 1.00 61.45  ? 381 ASP A O   1 
ATOM   7518 C  CB  . ASP F 6 367 ? 143.757 117.759 139.199 1.00 48.90  ? 381 ASP A CB  1 
ATOM   7519 C  CG  . ASP F 6 367 ? 144.502 116.667 138.468 1.00 70.01  ? 381 ASP A CG  1 
ATOM   7520 O  OD1 . ASP F 6 367 ? 144.962 116.909 137.334 1.00 72.59  ? 381 ASP A OD1 1 
ATOM   7521 O  OD2 . ASP F 6 367 ? 144.624 115.558 139.027 1.00 71.37  ? 381 ASP A OD2 1 
ATOM   7522 N  N   . ILE F 6 368 ? 143.254 120.713 140.286 1.00 40.02  ? 382 ILE A N   1 
ATOM   7523 C  CA  . ILE F 6 368 ? 142.344 121.660 140.925 1.00 36.69  ? 382 ILE A CA  1 
ATOM   7524 C  C   . ILE F 6 368 ? 142.031 122.818 139.983 1.00 49.33  ? 382 ILE A C   1 
ATOM   7525 O  O   . ILE F 6 368 ? 140.866 123.175 139.766 1.00 50.59  ? 382 ILE A O   1 
ATOM   7526 C  CB  . ILE F 6 368 ? 142.953 122.155 142.249 1.00 39.42  ? 382 ILE A CB  1 
ATOM   7527 C  CG1 . ILE F 6 368 ? 142.789 121.098 143.339 1.00 40.32  ? 382 ILE A CG1 1 
ATOM   7528 C  CG2 . ILE F 6 368 ? 142.330 123.461 142.676 1.00 43.78  ? 382 ILE A CG2 1 
ATOM   7529 C  CD1 . ILE F 6 368 ? 143.737 121.249 144.486 1.00 38.44  ? 382 ILE A CD1 1 
ATOM   7530 N  N   . ILE F 6 369 ? 143.073 123.404 139.393 1.00 53.39  ? 383 ILE A N   1 
ATOM   7531 C  CA  . ILE F 6 369 ? 142.895 124.553 138.512 1.00 46.66  ? 383 ILE A CA  1 
ATOM   7532 C  C   . ILE F 6 369 ? 142.249 124.139 137.199 1.00 48.52  ? 383 ILE A C   1 
ATOM   7533 O  O   . ILE F 6 369 ? 141.403 124.860 136.655 1.00 55.35  ? 383 ILE A O   1 
ATOM   7534 C  CB  . ILE F 6 369 ? 144.244 125.256 138.292 1.00 48.77  ? 383 ILE A CB  1 
ATOM   7535 C  CG1 . ILE F 6 369 ? 144.703 125.901 139.594 1.00 51.86  ? 383 ILE A CG1 1 
ATOM   7536 C  CG2 . ILE F 6 369 ? 144.130 126.298 137.207 1.00 51.59  ? 383 ILE A CG2 1 
ATOM   7537 C  CD1 . ILE F 6 369 ? 146.178 125.955 139.742 1.00 46.65  ? 383 ILE A CD1 1 
ATOM   7538 N  N   . GLN F 6 370 ? 142.634 122.981 136.660 1.00 50.60  ? 384 GLN A N   1 
ATOM   7539 C  CA  . GLN F 6 370 ? 142.002 122.506 135.435 1.00 32.78  ? 384 GLN A CA  1 
ATOM   7540 C  C   . GLN F 6 370 ? 140.506 122.326 135.631 1.00 42.06  ? 384 GLN A C   1 
ATOM   7541 O  O   . GLN F 6 370 ? 139.707 122.749 134.794 1.00 61.42  ? 384 GLN A O   1 
ATOM   7542 C  CB  . GLN F 6 370 ? 142.649 121.203 134.980 1.00 31.59  ? 384 GLN A CB  1 
ATOM   7543 C  CG  . GLN F 6 370 ? 143.849 121.415 134.098 1.00 46.69  ? 384 GLN A CG  1 
ATOM   7544 C  CD  . GLN F 6 370 ? 144.568 120.137 133.767 1.00 51.62  ? 384 GLN A CD  1 
ATOM   7545 O  OE1 . GLN F 6 370 ? 144.170 119.059 134.195 1.00 49.08  ? 384 GLN A OE1 1 
ATOM   7546 N  NE2 . GLN F 6 370 ? 145.637 120.248 132.995 1.00 51.35  ? 384 GLN A NE2 1 
ATOM   7547 N  N   . ARG F 6 371 ? 140.104 121.713 136.746 1.00 53.09  ? 385 ARG A N   1 
ATOM   7548 C  CA  . ARG F 6 371 ? 138.684 121.528 137.012 1.00 38.96  ? 385 ARG A CA  1 
ATOM   7549 C  C   . ARG F 6 371 ? 137.974 122.851 137.241 1.00 45.55  ? 385 ARG A C   1 
ATOM   7550 O  O   . ARG F 6 371 ? 136.844 123.025 136.780 1.00 61.05  ? 385 ARG A O   1 
ATOM   7551 C  CB  . ARG F 6 371 ? 138.491 120.605 138.209 1.00 45.97  ? 385 ARG A CB  1 
ATOM   7552 C  CG  . ARG F 6 371 ? 138.427 119.147 137.834 1.00 49.78  ? 385 ARG A CG  1 
ATOM   7553 C  CD  . ARG F 6 371 ? 138.516 118.242 139.037 1.00 55.77  ? 385 ARG A CD  1 
ATOM   7554 N  NE  . ARG F 6 371 ? 139.299 117.052 138.738 1.00 60.33  ? 385 ARG A NE  1 
ATOM   7555 C  CZ  . ARG F 6 371 ? 139.157 115.884 139.347 1.00 59.28  ? 385 ARG A CZ  1 
ATOM   7556 N  NH1 . ARG F 6 371 ? 138.265 115.707 140.303 1.00 60.25  ? 385 ARG A NH1 1 
ATOM   7557 N  NH2 . ARG F 6 371 ? 139.935 114.868 138.988 1.00 55.08  ? 385 ARG A NH2 1 
ATOM   7558 N  N   . MET F 6 372 ? 138.610 123.793 137.939 1.00 50.71  ? 386 MET A N   1 
ATOM   7559 C  CA  . MET F 6 372 ? 137.979 125.091 138.163 1.00 57.77  ? 386 MET A CA  1 
ATOM   7560 C  C   . MET F 6 372 ? 137.725 125.821 136.850 1.00 62.52  ? 386 MET A C   1 
ATOM   7561 O  O   . MET F 6 372 ? 136.645 126.388 136.642 1.00 65.56  ? 386 MET A O   1 
ATOM   7562 C  CB  . MET F 6 372 ? 138.847 125.940 139.086 1.00 57.26  ? 386 MET A CB  1 
ATOM   7563 C  CG  . MET F 6 372 ? 138.327 127.341 139.303 1.00 62.52  ? 386 MET A CG  1 
ATOM   7564 S  SD  . MET F 6 372 ? 139.346 128.291 140.442 1.00 85.96  ? 386 MET A SD  1 
ATOM   7565 C  CE  . MET F 6 372 ? 140.770 128.600 139.406 1.00 66.11  ? 386 MET A CE  1 
ATOM   7566 N  N   . HIS F 6 373 ? 138.703 125.807 135.945 1.00 63.71  ? 387 HIS A N   1 
ATOM   7567 C  CA  . HIS F 6 373 ? 138.532 126.483 134.663 1.00 44.33  ? 387 HIS A CA  1 
ATOM   7568 C  C   . HIS F 6 373 ? 137.521 125.758 133.782 1.00 44.89  ? 387 HIS A C   1 
ATOM   7569 O  O   . HIS F 6 373 ? 136.676 126.395 133.150 1.00 60.15  ? 387 HIS A O   1 
ATOM   7570 C  CB  . HIS F 6 373 ? 139.877 126.610 133.957 1.00 44.82  ? 387 HIS A CB  1 
ATOM   7571 C  CG  . HIS F 6 373 ? 140.705 127.751 134.451 1.00 60.09  ? 387 HIS A CG  1 
ATOM   7572 N  ND1 . HIS F 6 373 ? 142.026 127.611 134.813 1.00 64.04  ? 387 HIS A ND1 1 
ATOM   7573 C  CD2 . HIS F 6 373 ? 140.397 129.052 134.650 1.00 59.49  ? 387 HIS A CD2 1 
ATOM   7574 C  CE1 . HIS F 6 373 ? 142.499 128.778 135.208 1.00 57.09  ? 387 HIS A CE1 1 
ATOM   7575 N  NE2 . HIS F 6 373 ? 141.530 129.670 135.119 1.00 59.74  ? 387 HIS A NE2 1 
ATOM   7576 N  N   . LEU F 6 374 ? 137.584 124.425 133.733 1.00 42.63  ? 388 LEU A N   1 
ATOM   7577 C  CA  . LEU F 6 374 ? 136.608 123.664 132.963 1.00 35.52  ? 388 LEU A CA  1 
ATOM   7578 C  C   . LEU F 6 374 ? 135.194 123.907 133.460 1.00 42.28  ? 388 LEU A C   1 
ATOM   7579 O  O   . LEU F 6 374 ? 134.254 123.938 132.662 1.00 53.99  ? 388 LEU A O   1 
ATOM   7580 C  CB  . LEU F 6 374 ? 136.928 122.172 133.027 1.00 43.08  ? 388 LEU A CB  1 
ATOM   7581 C  CG  . LEU F 6 374 ? 138.091 121.606 132.217 1.00 47.63  ? 388 LEU A CG  1 
ATOM   7582 C  CD1 . LEU F 6 374 ? 138.394 120.197 132.671 1.00 43.81  ? 388 LEU A CD1 1 
ATOM   7583 C  CD2 . LEU F 6 374 ? 137.770 121.625 130.744 1.00 53.83  ? 388 LEU A CD2 1 
ATOM   7584 N  N   . ARG F 6 375 ? 135.015 124.066 134.770 1.00 61.66  ? 389 ARG A N   1 
ATOM   7585 C  CA  . ARG F 6 375 ? 133.692 124.346 135.308 1.00 57.47  ? 389 ARG A CA  1 
ATOM   7586 C  C   . ARG F 6 375 ? 133.256 125.777 135.029 1.00 64.69  ? 389 ARG A C   1 
ATOM   7587 O  O   . ARG F 6 375 ? 132.064 126.026 134.827 1.00 74.02  ? 389 ARG A O   1 
ATOM   7588 C  CB  . ARG F 6 375 ? 133.672 124.063 136.809 1.00 63.35  ? 389 ARG A CB  1 
ATOM   7589 C  CG  . ARG F 6 375 ? 132.391 124.454 137.505 1.00 66.26  ? 389 ARG A CG  1 
ATOM   7590 C  CD  . ARG F 6 375 ? 132.640 124.840 138.954 1.00 64.34  ? 389 ARG A CD  1 
ATOM   7591 N  NE  . ARG F 6 375 ? 131.446 125.356 139.613 1.00 69.97  ? 389 ARG A NE  1 
ATOM   7592 C  CZ  . ARG F 6 375 ? 130.348 124.651 139.854 1.00 75.55  ? 389 ARG A CZ  1 
ATOM   7593 N  NH1 . ARG F 6 375 ? 130.244 123.382 139.494 1.00 69.63  ? 389 ARG A NH1 1 
ATOM   7594 N  NH2 . ARG F 6 375 ? 129.329 125.232 140.479 1.00 74.05  ? 389 ARG A NH2 1 
ATOM   7595 N  N   . GLN F 6 376 ? 134.193 126.728 135.006 1.00 67.32  ? 390 GLN A N   1 
ATOM   7596 C  CA  . GLN F 6 376 ? 133.824 128.098 134.662 1.00 62.87  ? 390 GLN A CA  1 
ATOM   7597 C  C   . GLN F 6 376 ? 133.389 128.229 133.206 1.00 66.84  ? 390 GLN A C   1 
ATOM   7598 O  O   . GLN F 6 376 ? 132.504 129.035 132.902 1.00 72.72  ? 390 GLN A O   1 
ATOM   7599 C  CB  . GLN F 6 376 ? 134.984 129.046 134.964 1.00 59.11  ? 390 GLN A CB  1 
ATOM   7600 C  CG  . GLN F 6 376 ? 135.136 130.184 133.986 1.00 63.38  ? 390 GLN A CG  1 
ATOM   7601 C  CD  . GLN F 6 376 ? 136.379 131.004 134.237 1.00 73.78  ? 390 GLN A CD  1 
ATOM   7602 O  OE1 . GLN F 6 376 ? 137.324 130.542 134.873 1.00 81.49  ? 390 GLN A OE1 1 
ATOM   7603 N  NE2 . GLN F 6 376 ? 136.389 132.229 133.732 1.00 67.66  ? 390 GLN A NE2 1 
ATOM   7604 N  N   . TYR F 6 377 ? 133.970 127.447 132.300 1.00 60.75  ? 391 TYR A N   1 
ATOM   7605 C  CA  . TYR F 6 377 ? 133.598 127.489 130.890 1.00 53.62  ? 391 TYR A CA  1 
ATOM   7606 C  C   . TYR F 6 377 ? 132.370 126.648 130.571 1.00 58.23  ? 391 TYR A C   1 
ATOM   7607 O  O   . TYR F 6 377 ? 132.080 126.441 129.390 1.00 63.87  ? 391 TYR A O   1 
ATOM   7608 C  CB  . TYR F 6 377 ? 134.768 127.031 130.016 1.00 47.50  ? 391 TYR A CB  1 
ATOM   7609 C  CG  . TYR F 6 377 ? 136.031 127.835 130.201 1.00 51.45  ? 391 TYR A CG  1 
ATOM   7610 C  CD1 . TYR F 6 377 ? 135.981 129.159 130.589 1.00 56.22  ? 391 TYR A CD1 1 
ATOM   7611 C  CD2 . TYR F 6 377 ? 137.270 127.268 129.985 1.00 50.29  ? 391 TYR A CD2 1 
ATOM   7612 C  CE1 . TYR F 6 377 ? 137.129 129.891 130.763 1.00 58.73  ? 391 TYR A CE1 1 
ATOM   7613 C  CE2 . TYR F 6 377 ? 138.422 127.995 130.154 1.00 52.14  ? 391 TYR A CE2 1 
ATOM   7614 C  CZ  . TYR F 6 377 ? 138.346 129.306 130.546 1.00 59.43  ? 391 TYR A CZ  1 
ATOM   7615 O  OH  . TYR F 6 377 ? 139.490 130.039 130.717 1.00 61.36  ? 391 TYR A OH  1 
ATOM   7616 N  N   . GLU F 6 378 ? 131.649 126.167 131.584 1.00 63.19  ? 392 GLU A N   1 
ATOM   7617 C  CA  . GLU F 6 378 ? 130.458 125.336 131.402 1.00 62.93  ? 392 GLU A CA  1 
ATOM   7618 C  C   . GLU F 6 378 ? 130.754 124.084 130.585 1.00 65.13  ? 392 GLU A C   1 
ATOM   7619 O  O   . GLU F 6 378 ? 129.957 123.676 129.742 1.00 68.51  ? 392 GLU A O   1 
ATOM   7620 C  CB  . GLU F 6 378 ? 129.317 126.130 130.763 1.00 68.38  ? 392 GLU A CB  1 
ATOM   7621 C  CG  . GLU F 6 378 ? 128.412 126.823 131.765 1.00 72.43  ? 392 GLU A CG  1 
ATOM   7622 C  CD  . GLU F 6 378 ? 128.231 128.295 131.467 1.00 80.12  ? 392 GLU A CD  1 
ATOM   7623 O  OE1 . GLU F 6 378 ? 128.073 128.647 130.280 1.00 77.04  ? 392 GLU A OE1 1 
ATOM   7624 O  OE2 . GLU F 6 378 ? 128.251 129.100 132.419 1.00 83.79  ? 392 GLU A OE2 1 
ATOM   7625 N  N   . LEU F 6 379 ? 131.899 123.459 130.840 1.00 65.28  ? 393 LEU A N   1 
ATOM   7626 C  CA  . LEU F 6 379 ? 132.344 122.288 130.104 1.00 61.88  ? 393 LEU A CA  1 
ATOM   7627 C  C   . LEU F 6 379 ? 132.451 121.051 130.981 1.00 66.02  ? 393 LEU A C   1 
ATOM   7628 O  O   . LEU F 6 379 ? 132.424 119.932 130.459 1.00 68.05  ? 393 LEU A O   1 
ATOM   7629 C  CB  . LEU F 6 379 ? 133.697 122.577 129.447 1.00 61.20  ? 393 LEU A CB  1 
ATOM   7630 C  CG  . LEU F 6 379 ? 133.890 122.249 127.973 1.00 69.06  ? 393 LEU A CG  1 
ATOM   7631 C  CD1 . LEU F 6 379 ? 132.833 122.925 127.136 1.00 64.38  ? 393 LEU A CD1 1 
ATOM   7632 C  CD2 . LEU F 6 379 ? 135.265 122.706 127.544 1.00 69.25  ? 393 LEU A CD2 1 
ATOM   7633 N  N   . LEU F 6 380 ? 132.575 121.221 132.292 1.00 72.80  ? 394 LEU A N   1 
ATOM   7634 C  CA  . LEU F 6 380 ? 132.645 120.108 133.228 1.00 68.89  ? 394 LEU A CA  1 
ATOM   7635 C  C   . LEU F 6 380 ? 131.328 119.980 133.973 1.00 78.53  ? 394 LEU A C   1 
ATOM   7636 O  O   . LEU F 6 380 ? 130.754 120.980 134.402 1.00 76.99  ? 394 LEU A O   1 
ATOM   7637 C  CB  . LEU F 6 380 ? 133.788 120.306 134.222 1.00 64.96  ? 394 LEU A CB  1 
ATOM   7638 C  CG  . LEU F 6 380 ? 134.257 119.093 135.022 1.00 61.06  ? 394 LEU A CG  1 
ATOM   7639 C  CD1 . LEU F 6 380 ? 135.065 118.170 134.150 1.00 65.15  ? 394 LEU A CD1 1 
ATOM   7640 C  CD2 . LEU F 6 380 ? 135.059 119.528 136.226 1.00 68.17  ? 394 LEU A CD2 1 
ATOM   7641 O  OXT . LEU F 6 380 ? 130.813 118.881 134.176 1.00 84.62  ? 394 LEU A OXT 1 
HETATM 7642 CA CA  . CA  G 7 .   ? 128.167 148.100 98.861  1.00 72.42  ? 501 CA  R CA  1 
# 
