data_8W5V
# 
_entry.id   8W5V 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8W5V         pdb_00008w5v 10.2210/pdb8w5v/pdb 
WWPDB D_1300040618 ?            ?                   
EMDB  EMD-37305    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-02-26 ? 
2 'EM metadata'     1 0 2025-02-26 ? 
3 'Half map'        1 0 2025-02-26 1 
4 'Half map'        1 0 2025-02-26 2 
5 Image             1 0 2025-02-26 ? 
6 'Primary map'     1 0 2025-02-26 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Half map'        repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 Image             repository 'Initial release' ? ? 
6 6 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8W5V 
_pdbx_database_status.recvd_initial_deposition_date   2023-08-27 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure of QbN10K-Ab40' 
_pdbx_database_related.db_id          EMD-37305 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              zhup@ibp.ac.cn 
_pdbx_contact_author.name_first         Ping 
_pdbx_contact_author.name_last          Zhu 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-2648-3170 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Bao, K.Y.' 1 ? 
'Li, R.H.'  2 ? 
'Hua, Z.L.' 3 ? 
'Hou, B.D.' 4 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Cell Rep' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2211-1247 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            44 
_citation.language                  ? 
_citation.page_first                115334 
_citation.page_last                 115334 
_citation.title                     
'Competition propels, rather than limits, the success of low-affinity B cells in the germinal center response.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.celrep.2025.115334 
_citation.pdbx_database_id_PubMed   39955776 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Li, R.'  1 ? 
primary 'Bao, K.' 2 ? 
primary 'Liu, C.' 3 ? 
primary 'Ma, X.'  4 ? 
primary 'Hua, Z.' 5 ? 
primary 'Zhu, P.' 6 ? 
primary 'Hou, B.' 7 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'Light chain of Ab40'     12671.184 1 ? ? ? ? 
2 polymer man 'Heavy chain of Ab40'     13224.450 1 ? ? ? ? 
3 polymer man 'Minor capsid protein A1' 14283.149 2 ? ? ? ? 
# 
_entity_name_com.entity_id   3 
_entity_name_com.name        'Qb coat protein' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;VHSDIVMSQSPSSLAVSIGEKVTLTCKSSQSLLFSSNQKNYLAWYQQNPGQSPKLLIYWASTRESGVPDRFTGSGSGTDF
TLTISSVKAEDLAIYYCQQYFRYPAFGGGTKLEIK
;
;VHSDIVMSQSPSSLAVSIGEKVTLTCKSSQSLLFSSNQKNYLAWYQQNPGQSPKLLIYWASTRESGVPDRFTGSGSGTDF
TLTISSVKAEDLAIYYCQQYFRYPAFGGGTKLEIK
;
L   ? 
2 'polypeptide(L)' no no 
;VHSEVQLQQSGPELVKSGTSVKLSCKASGYSFTDHSLHWVKQSHGESLEWIGYFSPNNGGTIYNQKFMGKATLTVDRSSS
TAYMDLHNLTSADSAVYFCSTGWDYGPFDSWGQGTTLTVSS
;
;VHSEVQLQQSGPELVKSGTSVKLSCKASGYSFTDHSLHWVKQSHGESLEWIGYFSPNNGGTIYNQKFMGKATLTVDRSSS
TAYMDLHNLTSADSAVYFCSTGWDYGPFDSWGQGTTLTVSS
;
H   ? 
3 'polypeptide(L)' no no 
;MAKLETVTLGKIGKDGKQTLVLNPRGVNPTNGVASLSQAGAVPALEKRVTVSVSQPSRNRKNYKVQVKIQNPTACTANGS
CDPSVTRQAYADVTFSFTQYSTDEERAFVRTELAALLASPLLIDAIDQLNPAY
;
;MAKLETVTLGKIGKDGKQTLVLNPRGVNPTNGVASLSQAGAVPALEKRVTVSVSQPSRNRKNYKVQVKIQNPTACTANGS
CDPSVTRQAYADVTFSFTQYSTDEERAFVRTELAALLASPLLIDAIDQLNPAY
;
C,c ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   VAL n 
1 2   HIS n 
1 3   SER n 
1 4   ASP n 
1 5   ILE n 
1 6   VAL n 
1 7   MET n 
1 8   SER n 
1 9   GLN n 
1 10  SER n 
1 11  PRO n 
1 12  SER n 
1 13  SER n 
1 14  LEU n 
1 15  ALA n 
1 16  VAL n 
1 17  SER n 
1 18  ILE n 
1 19  GLY n 
1 20  GLU n 
1 21  LYS n 
1 22  VAL n 
1 23  THR n 
1 24  LEU n 
1 25  THR n 
1 26  CYS n 
1 27  LYS n 
1 28  SER n 
1 29  SER n 
1 30  GLN n 
1 31  SER n 
1 32  LEU n 
1 33  LEU n 
1 34  PHE n 
1 35  SER n 
1 36  SER n 
1 37  ASN n 
1 38  GLN n 
1 39  LYS n 
1 40  ASN n 
1 41  TYR n 
1 42  LEU n 
1 43  ALA n 
1 44  TRP n 
1 45  TYR n 
1 46  GLN n 
1 47  GLN n 
1 48  ASN n 
1 49  PRO n 
1 50  GLY n 
1 51  GLN n 
1 52  SER n 
1 53  PRO n 
1 54  LYS n 
1 55  LEU n 
1 56  LEU n 
1 57  ILE n 
1 58  TYR n 
1 59  TRP n 
1 60  ALA n 
1 61  SER n 
1 62  THR n 
1 63  ARG n 
1 64  GLU n 
1 65  SER n 
1 66  GLY n 
1 67  VAL n 
1 68  PRO n 
1 69  ASP n 
1 70  ARG n 
1 71  PHE n 
1 72  THR n 
1 73  GLY n 
1 74  SER n 
1 75  GLY n 
1 76  SER n 
1 77  GLY n 
1 78  THR n 
1 79  ASP n 
1 80  PHE n 
1 81  THR n 
1 82  LEU n 
1 83  THR n 
1 84  ILE n 
1 85  SER n 
1 86  SER n 
1 87  VAL n 
1 88  LYS n 
1 89  ALA n 
1 90  GLU n 
1 91  ASP n 
1 92  LEU n 
1 93  ALA n 
1 94  ILE n 
1 95  TYR n 
1 96  TYR n 
1 97  CYS n 
1 98  GLN n 
1 99  GLN n 
1 100 TYR n 
1 101 PHE n 
1 102 ARG n 
1 103 TYR n 
1 104 PRO n 
1 105 ALA n 
1 106 PHE n 
1 107 GLY n 
1 108 GLY n 
1 109 GLY n 
1 110 THR n 
1 111 LYS n 
1 112 LEU n 
1 113 GLU n 
1 114 ILE n 
1 115 LYS n 
2 1   VAL n 
2 2   HIS n 
2 3   SER n 
2 4   GLU n 
2 5   VAL n 
2 6   GLN n 
2 7   LEU n 
2 8   GLN n 
2 9   GLN n 
2 10  SER n 
2 11  GLY n 
2 12  PRO n 
2 13  GLU n 
2 14  LEU n 
2 15  VAL n 
2 16  LYS n 
2 17  SER n 
2 18  GLY n 
2 19  THR n 
2 20  SER n 
2 21  VAL n 
2 22  LYS n 
2 23  LEU n 
2 24  SER n 
2 25  CYS n 
2 26  LYS n 
2 27  ALA n 
2 28  SER n 
2 29  GLY n 
2 30  TYR n 
2 31  SER n 
2 32  PHE n 
2 33  THR n 
2 34  ASP n 
2 35  HIS n 
2 36  SER n 
2 37  LEU n 
2 38  HIS n 
2 39  TRP n 
2 40  VAL n 
2 41  LYS n 
2 42  GLN n 
2 43  SER n 
2 44  HIS n 
2 45  GLY n 
2 46  GLU n 
2 47  SER n 
2 48  LEU n 
2 49  GLU n 
2 50  TRP n 
2 51  ILE n 
2 52  GLY n 
2 53  TYR n 
2 54  PHE n 
2 55  SER n 
2 56  PRO n 
2 57  ASN n 
2 58  ASN n 
2 59  GLY n 
2 60  GLY n 
2 61  THR n 
2 62  ILE n 
2 63  TYR n 
2 64  ASN n 
2 65  GLN n 
2 66  LYS n 
2 67  PHE n 
2 68  MET n 
2 69  GLY n 
2 70  LYS n 
2 71  ALA n 
2 72  THR n 
2 73  LEU n 
2 74  THR n 
2 75  VAL n 
2 76  ASP n 
2 77  ARG n 
2 78  SER n 
2 79  SER n 
2 80  SER n 
2 81  THR n 
2 82  ALA n 
2 83  TYR n 
2 84  MET n 
2 85  ASP n 
2 86  LEU n 
2 87  HIS n 
2 88  ASN n 
2 89  LEU n 
2 90  THR n 
2 91  SER n 
2 92  ALA n 
2 93  ASP n 
2 94  SER n 
2 95  ALA n 
2 96  VAL n 
2 97  TYR n 
2 98  PHE n 
2 99  CYS n 
2 100 SER n 
2 101 THR n 
2 102 GLY n 
2 103 TRP n 
2 104 ASP n 
2 105 TYR n 
2 106 GLY n 
2 107 PRO n 
2 108 PHE n 
2 109 ASP n 
2 110 SER n 
2 111 TRP n 
2 112 GLY n 
2 113 GLN n 
2 114 GLY n 
2 115 THR n 
2 116 THR n 
2 117 LEU n 
2 118 THR n 
2 119 VAL n 
2 120 SER n 
2 121 SER n 
3 1   MET n 
3 2   ALA n 
3 3   LYS n 
3 4   LEU n 
3 5   GLU n 
3 6   THR n 
3 7   VAL n 
3 8   THR n 
3 9   LEU n 
3 10  GLY n 
3 11  LYS n 
3 12  ILE n 
3 13  GLY n 
3 14  LYS n 
3 15  ASP n 
3 16  GLY n 
3 17  LYS n 
3 18  GLN n 
3 19  THR n 
3 20  LEU n 
3 21  VAL n 
3 22  LEU n 
3 23  ASN n 
3 24  PRO n 
3 25  ARG n 
3 26  GLY n 
3 27  VAL n 
3 28  ASN n 
3 29  PRO n 
3 30  THR n 
3 31  ASN n 
3 32  GLY n 
3 33  VAL n 
3 34  ALA n 
3 35  SER n 
3 36  LEU n 
3 37  SER n 
3 38  GLN n 
3 39  ALA n 
3 40  GLY n 
3 41  ALA n 
3 42  VAL n 
3 43  PRO n 
3 44  ALA n 
3 45  LEU n 
3 46  GLU n 
3 47  LYS n 
3 48  ARG n 
3 49  VAL n 
3 50  THR n 
3 51  VAL n 
3 52  SER n 
3 53  VAL n 
3 54  SER n 
3 55  GLN n 
3 56  PRO n 
3 57  SER n 
3 58  ARG n 
3 59  ASN n 
3 60  ARG n 
3 61  LYS n 
3 62  ASN n 
3 63  TYR n 
3 64  LYS n 
3 65  VAL n 
3 66  GLN n 
3 67  VAL n 
3 68  LYS n 
3 69  ILE n 
3 70  GLN n 
3 71  ASN n 
3 72  PRO n 
3 73  THR n 
3 74  ALA n 
3 75  CYS n 
3 76  THR n 
3 77  ALA n 
3 78  ASN n 
3 79  GLY n 
3 80  SER n 
3 81  CYS n 
3 82  ASP n 
3 83  PRO n 
3 84  SER n 
3 85  VAL n 
3 86  THR n 
3 87  ARG n 
3 88  GLN n 
3 89  ALA n 
3 90  TYR n 
3 91  ALA n 
3 92  ASP n 
3 93  VAL n 
3 94  THR n 
3 95  PHE n 
3 96  SER n 
3 97  PHE n 
3 98  THR n 
3 99  GLN n 
3 100 TYR n 
3 101 SER n 
3 102 THR n 
3 103 ASP n 
3 104 GLU n 
3 105 GLU n 
3 106 ARG n 
3 107 ALA n 
3 108 PHE n 
3 109 VAL n 
3 110 ARG n 
3 111 THR n 
3 112 GLU n 
3 113 LEU n 
3 114 ALA n 
3 115 ALA n 
3 116 LEU n 
3 117 LEU n 
3 118 ALA n 
3 119 SER n 
3 120 PRO n 
3 121 LEU n 
3 122 LEU n 
3 123 ILE n 
3 124 ASP n 
3 125 ALA n 
3 126 ILE n 
3 127 ASP n 
3 128 GLN n 
3 129 LEU n 
3 130 ASN n 
3 131 PRO n 
3 132 ALA n 
3 133 TYR n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 115 ? ? ? ? ? ? ? ? ? 'Mus musculus'            10090   ? ? ? ? ? ? ? ? 'Homo sapiens'     9606 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 121 ? ? ? ? ? ? ? ? ? 'Mus musculus'            10090   ? ? ? ? ? ? ? ? 'Homo sapiens'     9606 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 133 ? ? ? ? ? ? ? ? ? 'Escherichia phage Qbeta' 2789016 ? ? ? ? ? ? ? ? 'Escherichia coli' 562  
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   VAL 1   1   ?   ?   ?   L . n 
A 1 2   HIS 2   2   ?   ?   ?   L . n 
A 1 3   SER 3   3   ?   ?   ?   L . n 
A 1 4   ASP 4   4   ?   ?   ?   L . n 
A 1 5   ILE 5   5   5   ILE ILE L . n 
A 1 6   VAL 6   6   6   VAL VAL L . n 
A 1 7   MET 7   7   7   MET MET L . n 
A 1 8   SER 8   8   8   SER SER L . n 
A 1 9   GLN 9   9   9   GLN GLN L . n 
A 1 10  SER 10  10  10  SER SER L . n 
A 1 11  PRO 11  11  11  PRO PRO L . n 
A 1 12  SER 12  12  12  SER SER L . n 
A 1 13  SER 13  13  13  SER SER L . n 
A 1 14  LEU 14  14  14  LEU LEU L . n 
A 1 15  ALA 15  15  15  ALA ALA L . n 
A 1 16  VAL 16  16  16  VAL VAL L . n 
A 1 17  SER 17  17  17  SER SER L . n 
A 1 18  ILE 18  18  18  ILE ILE L . n 
A 1 19  GLY 19  19  19  GLY GLY L . n 
A 1 20  GLU 20  20  20  GLU GLU L . n 
A 1 21  LYS 21  21  21  LYS LYS L . n 
A 1 22  VAL 22  22  22  VAL VAL L . n 
A 1 23  THR 23  23  23  THR THR L . n 
A 1 24  LEU 24  24  24  LEU LEU L . n 
A 1 25  THR 25  25  25  THR THR L . n 
A 1 26  CYS 26  26  26  CYS CYS L . n 
A 1 27  LYS 27  27  27  LYS LYS L . n 
A 1 28  SER 28  28  28  SER SER L . n 
A 1 29  SER 29  29  29  SER SER L . n 
A 1 30  GLN 30  30  30  GLN GLN L . n 
A 1 31  SER 31  31  31  SER SER L . n 
A 1 32  LEU 32  32  32  LEU LEU L . n 
A 1 33  LEU 33  33  33  LEU LEU L . n 
A 1 34  PHE 34  34  34  PHE PHE L . n 
A 1 35  SER 35  35  35  SER SER L . n 
A 1 36  SER 36  36  36  SER SER L . n 
A 1 37  ASN 37  37  37  ASN ASN L . n 
A 1 38  GLN 38  38  38  GLN GLN L . n 
A 1 39  LYS 39  39  39  LYS LYS L . n 
A 1 40  ASN 40  40  40  ASN ASN L . n 
A 1 41  TYR 41  41  41  TYR TYR L . n 
A 1 42  LEU 42  42  42  LEU LEU L . n 
A 1 43  ALA 43  43  43  ALA ALA L . n 
A 1 44  TRP 44  44  44  TRP TRP L . n 
A 1 45  TYR 45  45  45  TYR TYR L . n 
A 1 46  GLN 46  46  46  GLN GLN L . n 
A 1 47  GLN 47  47  47  GLN GLN L . n 
A 1 48  ASN 48  48  48  ASN ASN L . n 
A 1 49  PRO 49  49  49  PRO PRO L . n 
A 1 50  GLY 50  50  50  GLY GLY L . n 
A 1 51  GLN 51  51  51  GLN GLN L . n 
A 1 52  SER 52  52  52  SER SER L . n 
A 1 53  PRO 53  53  53  PRO PRO L . n 
A 1 54  LYS 54  54  54  LYS LYS L . n 
A 1 55  LEU 55  55  55  LEU LEU L . n 
A 1 56  LEU 56  56  56  LEU LEU L . n 
A 1 57  ILE 57  57  57  ILE ILE L . n 
A 1 58  TYR 58  58  58  TYR TYR L . n 
A 1 59  TRP 59  59  59  TRP TRP L . n 
A 1 60  ALA 60  60  60  ALA ALA L . n 
A 1 61  SER 61  61  61  SER SER L . n 
A 1 62  THR 62  62  62  THR THR L . n 
A 1 63  ARG 63  63  63  ARG ARG L . n 
A 1 64  GLU 64  64  64  GLU GLU L . n 
A 1 65  SER 65  65  65  SER SER L . n 
A 1 66  GLY 66  66  66  GLY GLY L . n 
A 1 67  VAL 67  67  67  VAL VAL L . n 
A 1 68  PRO 68  68  68  PRO PRO L . n 
A 1 69  ASP 69  69  69  ASP ASP L . n 
A 1 70  ARG 70  70  70  ARG ARG L . n 
A 1 71  PHE 71  71  71  PHE PHE L . n 
A 1 72  THR 72  72  72  THR THR L . n 
A 1 73  GLY 73  73  73  GLY GLY L . n 
A 1 74  SER 74  74  74  SER SER L . n 
A 1 75  GLY 75  75  75  GLY GLY L . n 
A 1 76  SER 76  76  76  SER SER L . n 
A 1 77  GLY 77  77  77  GLY GLY L . n 
A 1 78  THR 78  78  78  THR THR L . n 
A 1 79  ASP 79  79  79  ASP ASP L . n 
A 1 80  PHE 80  80  80  PHE PHE L . n 
A 1 81  THR 81  81  81  THR THR L . n 
A 1 82  LEU 82  82  82  LEU LEU L . n 
A 1 83  THR 83  83  83  THR THR L . n 
A 1 84  ILE 84  84  84  ILE ILE L . n 
A 1 85  SER 85  85  85  SER SER L . n 
A 1 86  SER 86  86  86  SER SER L . n 
A 1 87  VAL 87  87  87  VAL VAL L . n 
A 1 88  LYS 88  88  88  LYS LYS L . n 
A 1 89  ALA 89  89  89  ALA ALA L . n 
A 1 90  GLU 90  90  90  GLU GLU L . n 
A 1 91  ASP 91  91  91  ASP ASP L . n 
A 1 92  LEU 92  92  92  LEU LEU L . n 
A 1 93  ALA 93  93  93  ALA ALA L . n 
A 1 94  ILE 94  94  94  ILE ILE L . n 
A 1 95  TYR 95  95  95  TYR TYR L . n 
A 1 96  TYR 96  96  96  TYR TYR L . n 
A 1 97  CYS 97  97  97  CYS CYS L . n 
A 1 98  GLN 98  98  98  GLN GLN L . n 
A 1 99  GLN 99  99  99  GLN GLN L . n 
A 1 100 TYR 100 100 100 TYR TYR L . n 
A 1 101 PHE 101 101 101 PHE PHE L . n 
A 1 102 ARG 102 102 102 ARG ARG L . n 
A 1 103 TYR 103 103 103 TYR TYR L . n 
A 1 104 PRO 104 104 104 PRO PRO L . n 
A 1 105 ALA 105 105 105 ALA ALA L . n 
A 1 106 PHE 106 106 106 PHE PHE L . n 
A 1 107 GLY 107 107 107 GLY GLY L . n 
A 1 108 GLY 108 108 108 GLY GLY L . n 
A 1 109 GLY 109 109 109 GLY GLY L . n 
A 1 110 THR 110 110 110 THR THR L . n 
A 1 111 LYS 111 111 ?   ?   ?   L . n 
A 1 112 LEU 112 112 ?   ?   ?   L . n 
A 1 113 GLU 113 113 ?   ?   ?   L . n 
A 1 114 ILE 114 114 ?   ?   ?   L . n 
A 1 115 LYS 115 115 ?   ?   ?   L . n 
B 2 1   VAL 1   1   ?   ?   ?   H . n 
B 2 2   HIS 2   2   ?   ?   ?   H . n 
B 2 3   SER 3   3   ?   ?   ?   H . n 
B 2 4   GLU 4   4   ?   ?   ?   H . n 
B 2 5   VAL 5   5   5   VAL VAL H . n 
B 2 6   GLN 6   6   6   GLN GLN H . n 
B 2 7   LEU 7   7   7   LEU LEU H . n 
B 2 8   GLN 8   8   8   GLN GLN H . n 
B 2 9   GLN 9   9   9   GLN GLN H . n 
B 2 10  SER 10  10  10  SER SER H . n 
B 2 11  GLY 11  11  11  GLY GLY H . n 
B 2 12  PRO 12  12  12  PRO PRO H . n 
B 2 13  GLU 13  13  13  GLU GLU H . n 
B 2 14  LEU 14  14  14  LEU LEU H . n 
B 2 15  VAL 15  15  15  VAL VAL H . n 
B 2 16  LYS 16  16  16  LYS LYS H . n 
B 2 17  SER 17  17  17  SER SER H . n 
B 2 18  GLY 18  18  18  GLY GLY H . n 
B 2 19  THR 19  19  19  THR THR H . n 
B 2 20  SER 20  20  20  SER SER H . n 
B 2 21  VAL 21  21  21  VAL VAL H . n 
B 2 22  LYS 22  22  22  LYS LYS H . n 
B 2 23  LEU 23  23  23  LEU LEU H . n 
B 2 24  SER 24  24  24  SER SER H . n 
B 2 25  CYS 25  25  25  CYS CYS H . n 
B 2 26  LYS 26  26  26  LYS LYS H . n 
B 2 27  ALA 27  27  27  ALA ALA H . n 
B 2 28  SER 28  28  28  SER SER H . n 
B 2 29  GLY 29  29  29  GLY GLY H . n 
B 2 30  TYR 30  30  30  TYR TYR H . n 
B 2 31  SER 31  31  31  SER SER H . n 
B 2 32  PHE 32  32  32  PHE PHE H . n 
B 2 33  THR 33  33  33  THR THR H . n 
B 2 34  ASP 34  34  34  ASP ASP H . n 
B 2 35  HIS 35  35  35  HIS HIS H . n 
B 2 36  SER 36  36  36  SER SER H . n 
B 2 37  LEU 37  37  37  LEU LEU H . n 
B 2 38  HIS 38  38  38  HIS HIS H . n 
B 2 39  TRP 39  39  39  TRP TRP H . n 
B 2 40  VAL 40  40  40  VAL VAL H . n 
B 2 41  LYS 41  41  41  LYS LYS H . n 
B 2 42  GLN 42  42  42  GLN GLN H . n 
B 2 43  SER 43  43  43  SER SER H . n 
B 2 44  HIS 44  44  44  HIS HIS H . n 
B 2 45  GLY 45  45  45  GLY GLY H . n 
B 2 46  GLU 46  46  46  GLU GLU H . n 
B 2 47  SER 47  47  47  SER SER H . n 
B 2 48  LEU 48  48  48  LEU LEU H . n 
B 2 49  GLU 49  49  49  GLU GLU H . n 
B 2 50  TRP 50  50  50  TRP TRP H . n 
B 2 51  ILE 51  51  51  ILE ILE H . n 
B 2 52  GLY 52  52  52  GLY GLY H . n 
B 2 53  TYR 53  53  53  TYR TYR H . n 
B 2 54  PHE 54  54  54  PHE PHE H . n 
B 2 55  SER 55  55  55  SER SER H . n 
B 2 56  PRO 56  56  56  PRO PRO H . n 
B 2 57  ASN 57  57  57  ASN ASN H . n 
B 2 58  ASN 58  58  58  ASN ASN H . n 
B 2 59  GLY 59  59  59  GLY GLY H . n 
B 2 60  GLY 60  60  60  GLY GLY H . n 
B 2 61  THR 61  61  61  THR THR H . n 
B 2 62  ILE 62  62  62  ILE ILE H . n 
B 2 63  TYR 63  63  63  TYR TYR H . n 
B 2 64  ASN 64  64  64  ASN ASN H . n 
B 2 65  GLN 65  65  65  GLN GLN H . n 
B 2 66  LYS 66  66  66  LYS LYS H . n 
B 2 67  PHE 67  67  67  PHE PHE H . n 
B 2 68  MET 68  68  68  MET MET H . n 
B 2 69  GLY 69  69  69  GLY GLY H . n 
B 2 70  LYS 70  70  70  LYS LYS H . n 
B 2 71  ALA 71  71  71  ALA ALA H . n 
B 2 72  THR 72  72  72  THR THR H . n 
B 2 73  LEU 73  73  73  LEU LEU H . n 
B 2 74  THR 74  74  74  THR THR H . n 
B 2 75  VAL 75  75  75  VAL VAL H . n 
B 2 76  ASP 76  76  76  ASP ASP H . n 
B 2 77  ARG 77  77  77  ARG ARG H . n 
B 2 78  SER 78  78  78  SER SER H . n 
B 2 79  SER 79  79  79  SER SER H . n 
B 2 80  SER 80  80  80  SER SER H . n 
B 2 81  THR 81  81  81  THR THR H . n 
B 2 82  ALA 82  82  82  ALA ALA H . n 
B 2 83  TYR 83  83  83  TYR TYR H . n 
B 2 84  MET 84  84  84  MET MET H . n 
B 2 85  ASP 85  85  85  ASP ASP H . n 
B 2 86  LEU 86  86  86  LEU LEU H . n 
B 2 87  HIS 87  87  87  HIS HIS H . n 
B 2 88  ASN 88  88  88  ASN ASN H . n 
B 2 89  LEU 89  89  89  LEU LEU H . n 
B 2 90  THR 90  90  90  THR THR H . n 
B 2 91  SER 91  91  91  SER SER H . n 
B 2 92  ALA 92  92  92  ALA ALA H . n 
B 2 93  ASP 93  93  93  ASP ASP H . n 
B 2 94  SER 94  94  94  SER SER H . n 
B 2 95  ALA 95  95  95  ALA ALA H . n 
B 2 96  VAL 96  96  96  VAL VAL H . n 
B 2 97  TYR 97  97  97  TYR TYR H . n 
B 2 98  PHE 98  98  98  PHE PHE H . n 
B 2 99  CYS 99  99  99  CYS CYS H . n 
B 2 100 SER 100 100 100 SER SER H . n 
B 2 101 THR 101 101 101 THR THR H . n 
B 2 102 GLY 102 102 102 GLY GLY H . n 
B 2 103 TRP 103 103 103 TRP TRP H . n 
B 2 104 ASP 104 104 104 ASP ASP H . n 
B 2 105 TYR 105 105 105 TYR TYR H . n 
B 2 106 GLY 106 106 106 GLY GLY H . n 
B 2 107 PRO 107 107 107 PRO PRO H . n 
B 2 108 PHE 108 108 108 PHE PHE H . n 
B 2 109 ASP 109 109 109 ASP ASP H . n 
B 2 110 SER 110 110 110 SER SER H . n 
B 2 111 TRP 111 111 111 TRP TRP H . n 
B 2 112 GLY 112 112 112 GLY GLY H . n 
B 2 113 GLN 113 113 113 GLN GLN H . n 
B 2 114 GLY 114 114 114 GLY GLY H . n 
B 2 115 THR 115 115 115 THR THR H . n 
B 2 116 THR 116 116 116 THR THR H . n 
B 2 117 LEU 117 117 117 LEU LEU H . n 
B 2 118 THR 118 118 ?   ?   ?   H . n 
B 2 119 VAL 119 119 ?   ?   ?   H . n 
B 2 120 SER 120 120 ?   ?   ?   H . n 
B 2 121 SER 121 121 ?   ?   ?   H . n 
C 3 1   MET 1   0   ?   ?   ?   C . n 
C 3 2   ALA 2   1   1   ALA ALA C . n 
C 3 3   LYS 3   2   2   LYS LYS C . n 
C 3 4   LEU 4   3   3   LEU LEU C . n 
C 3 5   GLU 5   4   4   GLU GLU C . n 
C 3 6   THR 6   5   5   THR THR C . n 
C 3 7   VAL 7   6   6   VAL VAL C . n 
C 3 8   THR 8   7   7   THR THR C . n 
C 3 9   LEU 9   8   8   LEU LEU C . n 
C 3 10  GLY 10  9   9   GLY GLY C . n 
C 3 11  LYS 11  10  10  LYS LYS C . n 
C 3 12  ILE 12  11  11  ILE ILE C . n 
C 3 13  GLY 13  12  12  GLY GLY C . n 
C 3 14  LYS 14  13  13  LYS LYS C . n 
C 3 15  ASP 15  14  14  ASP ASP C . n 
C 3 16  GLY 16  15  15  GLY GLY C . n 
C 3 17  LYS 17  16  16  LYS LYS C . n 
C 3 18  GLN 18  17  17  GLN GLN C . n 
C 3 19  THR 19  18  18  THR THR C . n 
C 3 20  LEU 20  19  19  LEU LEU C . n 
C 3 21  VAL 21  20  20  VAL VAL C . n 
C 3 22  LEU 22  21  21  LEU LEU C . n 
C 3 23  ASN 23  22  22  ASN ASN C . n 
C 3 24  PRO 24  23  23  PRO PRO C . n 
C 3 25  ARG 25  24  24  ARG ARG C . n 
C 3 26  GLY 26  25  25  GLY GLY C . n 
C 3 27  VAL 27  26  26  VAL VAL C . n 
C 3 28  ASN 28  27  27  ASN ASN C . n 
C 3 29  PRO 29  28  28  PRO PRO C . n 
C 3 30  THR 30  29  29  THR THR C . n 
C 3 31  ASN 31  30  30  ASN ASN C . n 
C 3 32  GLY 32  31  31  GLY GLY C . n 
C 3 33  VAL 33  32  32  VAL VAL C . n 
C 3 34  ALA 34  33  33  ALA ALA C . n 
C 3 35  SER 35  34  34  SER SER C . n 
C 3 36  LEU 36  35  35  LEU LEU C . n 
C 3 37  SER 37  36  36  SER SER C . n 
C 3 38  GLN 38  37  37  GLN GLN C . n 
C 3 39  ALA 39  38  38  ALA ALA C . n 
C 3 40  GLY 40  39  39  GLY GLY C . n 
C 3 41  ALA 41  40  40  ALA ALA C . n 
C 3 42  VAL 42  41  41  VAL VAL C . n 
C 3 43  PRO 43  42  42  PRO PRO C . n 
C 3 44  ALA 44  43  43  ALA ALA C . n 
C 3 45  LEU 45  44  44  LEU LEU C . n 
C 3 46  GLU 46  45  45  GLU GLU C . n 
C 3 47  LYS 47  46  46  LYS LYS C . n 
C 3 48  ARG 48  47  47  ARG ARG C . n 
C 3 49  VAL 49  48  48  VAL VAL C . n 
C 3 50  THR 50  49  49  THR THR C . n 
C 3 51  VAL 51  50  50  VAL VAL C . n 
C 3 52  SER 52  51  51  SER SER C . n 
C 3 53  VAL 53  52  52  VAL VAL C . n 
C 3 54  SER 54  53  53  SER SER C . n 
C 3 55  GLN 55  54  54  GLN GLN C . n 
C 3 56  PRO 56  55  55  PRO PRO C . n 
C 3 57  SER 57  56  ?   ?   ?   C . n 
C 3 58  ARG 58  57  ?   ?   ?   C . n 
C 3 59  ASN 59  58  ?   ?   ?   C . n 
C 3 60  ARG 60  59  ?   ?   ?   C . n 
C 3 61  LYS 61  60  ?   ?   ?   C . n 
C 3 62  ASN 62  61  61  ASN ASN C . n 
C 3 63  TYR 63  62  62  TYR TYR C . n 
C 3 64  LYS 64  63  63  LYS LYS C . n 
C 3 65  VAL 65  64  64  VAL VAL C . n 
C 3 66  GLN 66  65  65  GLN GLN C . n 
C 3 67  VAL 67  66  66  VAL VAL C . n 
C 3 68  LYS 68  67  67  LYS LYS C . n 
C 3 69  ILE 69  68  68  ILE ILE C . n 
C 3 70  GLN 70  69  69  GLN GLN C . n 
C 3 71  ASN 71  70  70  ASN ASN C . n 
C 3 72  PRO 72  71  71  PRO PRO C . n 
C 3 73  THR 73  72  72  THR THR C . n 
C 3 74  ALA 74  73  73  ALA ALA C . n 
C 3 75  CYS 75  74  74  CYS CYS C . n 
C 3 76  THR 76  75  75  THR THR C . n 
C 3 77  ALA 77  76  76  ALA ALA C . n 
C 3 78  ASN 78  77  77  ASN ASN C . n 
C 3 79  GLY 79  78  78  GLY GLY C . n 
C 3 80  SER 80  79  79  SER SER C . n 
C 3 81  CYS 81  80  80  CYS CYS C . n 
C 3 82  ASP 82  81  81  ASP ASP C . n 
C 3 83  PRO 83  82  82  PRO PRO C . n 
C 3 84  SER 84  83  83  SER SER C . n 
C 3 85  VAL 85  84  84  VAL VAL C . n 
C 3 86  THR 86  85  85  THR THR C . n 
C 3 87  ARG 87  86  86  ARG ARG C . n 
C 3 88  GLN 88  87  87  GLN GLN C . n 
C 3 89  ALA 89  88  88  ALA ALA C . n 
C 3 90  TYR 90  89  89  TYR TYR C . n 
C 3 91  ALA 91  90  90  ALA ALA C . n 
C 3 92  ASP 92  91  91  ASP ASP C . n 
C 3 93  VAL 93  92  92  VAL VAL C . n 
C 3 94  THR 94  93  93  THR THR C . n 
C 3 95  PHE 95  94  94  PHE PHE C . n 
C 3 96  SER 96  95  95  SER SER C . n 
C 3 97  PHE 97  96  96  PHE PHE C . n 
C 3 98  THR 98  97  97  THR THR C . n 
C 3 99  GLN 99  98  98  GLN GLN C . n 
C 3 100 TYR 100 99  99  TYR TYR C . n 
C 3 101 SER 101 100 100 SER SER C . n 
C 3 102 THR 102 101 101 THR THR C . n 
C 3 103 ASP 103 102 102 ASP ASP C . n 
C 3 104 GLU 104 103 103 GLU GLU C . n 
C 3 105 GLU 105 104 104 GLU GLU C . n 
C 3 106 ARG 106 105 105 ARG ARG C . n 
C 3 107 ALA 107 106 106 ALA ALA C . n 
C 3 108 PHE 108 107 107 PHE PHE C . n 
C 3 109 VAL 109 108 108 VAL VAL C . n 
C 3 110 ARG 110 109 109 ARG ARG C . n 
C 3 111 THR 111 110 110 THR THR C . n 
C 3 112 GLU 112 111 111 GLU GLU C . n 
C 3 113 LEU 113 112 112 LEU LEU C . n 
C 3 114 ALA 114 113 113 ALA ALA C . n 
C 3 115 ALA 115 114 114 ALA ALA C . n 
C 3 116 LEU 116 115 115 LEU LEU C . n 
C 3 117 LEU 117 116 116 LEU LEU C . n 
C 3 118 ALA 118 117 117 ALA ALA C . n 
C 3 119 SER 119 118 118 SER SER C . n 
C 3 120 PRO 120 119 119 PRO PRO C . n 
C 3 121 LEU 121 120 120 LEU LEU C . n 
C 3 122 LEU 122 121 121 LEU LEU C . n 
C 3 123 ILE 123 122 122 ILE ILE C . n 
C 3 124 ASP 124 123 123 ASP ASP C . n 
C 3 125 ALA 125 124 124 ALA ALA C . n 
C 3 126 ILE 126 125 125 ILE ILE C . n 
C 3 127 ASP 127 126 126 ASP ASP C . n 
C 3 128 GLN 128 127 127 GLN GLN C . n 
C 3 129 LEU 129 128 128 LEU LEU C . n 
C 3 130 ASN 130 129 129 ASN ASN C . n 
C 3 131 PRO 131 130 130 PRO PRO C . n 
C 3 132 ALA 132 131 131 ALA ALA C . n 
C 3 133 TYR 133 132 ?   ?   ?   C . n 
D 3 1   MET 1   0   ?   ?   ?   c . n 
D 3 2   ALA 2   1   1   ALA ALA c . n 
D 3 3   LYS 3   2   2   LYS LYS c . n 
D 3 4   LEU 4   3   3   LEU LEU c . n 
D 3 5   GLU 5   4   4   GLU GLU c . n 
D 3 6   THR 6   5   5   THR THR c . n 
D 3 7   VAL 7   6   6   VAL VAL c . n 
D 3 8   THR 8   7   7   THR THR c . n 
D 3 9   LEU 9   8   8   LEU LEU c . n 
D 3 10  GLY 10  9   9   GLY GLY c . n 
D 3 11  LYS 11  10  10  LYS LYS c . n 
D 3 12  ILE 12  11  11  ILE ILE c . n 
D 3 13  GLY 13  12  12  GLY GLY c . n 
D 3 14  LYS 14  13  13  LYS LYS c . n 
D 3 15  ASP 15  14  14  ASP ASP c . n 
D 3 16  GLY 16  15  15  GLY GLY c . n 
D 3 17  LYS 17  16  16  LYS LYS c . n 
D 3 18  GLN 18  17  17  GLN GLN c . n 
D 3 19  THR 19  18  18  THR THR c . n 
D 3 20  LEU 20  19  19  LEU LEU c . n 
D 3 21  VAL 21  20  20  VAL VAL c . n 
D 3 22  LEU 22  21  21  LEU LEU c . n 
D 3 23  ASN 23  22  22  ASN ASN c . n 
D 3 24  PRO 24  23  23  PRO PRO c . n 
D 3 25  ARG 25  24  24  ARG ARG c . n 
D 3 26  GLY 26  25  25  GLY GLY c . n 
D 3 27  VAL 27  26  26  VAL VAL c . n 
D 3 28  ASN 28  27  27  ASN ASN c . n 
D 3 29  PRO 29  28  28  PRO PRO c . n 
D 3 30  THR 30  29  29  THR THR c . n 
D 3 31  ASN 31  30  30  ASN ASN c . n 
D 3 32  GLY 32  31  31  GLY GLY c . n 
D 3 33  VAL 33  32  32  VAL VAL c . n 
D 3 34  ALA 34  33  33  ALA ALA c . n 
D 3 35  SER 35  34  34  SER SER c . n 
D 3 36  LEU 36  35  35  LEU LEU c . n 
D 3 37  SER 37  36  36  SER SER c . n 
D 3 38  GLN 38  37  37  GLN GLN c . n 
D 3 39  ALA 39  38  38  ALA ALA c . n 
D 3 40  GLY 40  39  39  GLY GLY c . n 
D 3 41  ALA 41  40  40  ALA ALA c . n 
D 3 42  VAL 42  41  41  VAL VAL c . n 
D 3 43  PRO 43  42  42  PRO PRO c . n 
D 3 44  ALA 44  43  43  ALA ALA c . n 
D 3 45  LEU 45  44  44  LEU LEU c . n 
D 3 46  GLU 46  45  45  GLU GLU c . n 
D 3 47  LYS 47  46  46  LYS LYS c . n 
D 3 48  ARG 48  47  47  ARG ARG c . n 
D 3 49  VAL 49  48  48  VAL VAL c . n 
D 3 50  THR 50  49  49  THR THR c . n 
D 3 51  VAL 51  50  50  VAL VAL c . n 
D 3 52  SER 52  51  51  SER SER c . n 
D 3 53  VAL 53  52  52  VAL VAL c . n 
D 3 54  SER 54  53  53  SER SER c . n 
D 3 55  GLN 55  54  54  GLN GLN c . n 
D 3 56  PRO 56  55  55  PRO PRO c . n 
D 3 57  SER 57  56  ?   ?   ?   c . n 
D 3 58  ARG 58  57  ?   ?   ?   c . n 
D 3 59  ASN 59  58  ?   ?   ?   c . n 
D 3 60  ARG 60  59  ?   ?   ?   c . n 
D 3 61  LYS 61  60  60  LYS LYS c . n 
D 3 62  ASN 62  61  61  ASN ASN c . n 
D 3 63  TYR 63  62  62  TYR TYR c . n 
D 3 64  LYS 64  63  63  LYS LYS c . n 
D 3 65  VAL 65  64  64  VAL VAL c . n 
D 3 66  GLN 66  65  65  GLN GLN c . n 
D 3 67  VAL 67  66  66  VAL VAL c . n 
D 3 68  LYS 68  67  67  LYS LYS c . n 
D 3 69  ILE 69  68  68  ILE ILE c . n 
D 3 70  GLN 70  69  69  GLN GLN c . n 
D 3 71  ASN 71  70  70  ASN ASN c . n 
D 3 72  PRO 72  71  71  PRO PRO c . n 
D 3 73  THR 73  72  72  THR THR c . n 
D 3 74  ALA 74  73  73  ALA ALA c . n 
D 3 75  CYS 75  74  74  CYS CYS c . n 
D 3 76  THR 76  75  75  THR THR c . n 
D 3 77  ALA 77  76  76  ALA ALA c . n 
D 3 78  ASN 78  77  77  ASN ASN c . n 
D 3 79  GLY 79  78  78  GLY GLY c . n 
D 3 80  SER 80  79  79  SER SER c . n 
D 3 81  CYS 81  80  80  CYS CYS c . n 
D 3 82  ASP 82  81  81  ASP ASP c . n 
D 3 83  PRO 83  82  82  PRO PRO c . n 
D 3 84  SER 84  83  83  SER SER c . n 
D 3 85  VAL 85  84  84  VAL VAL c . n 
D 3 86  THR 86  85  85  THR THR c . n 
D 3 87  ARG 87  86  86  ARG ARG c . n 
D 3 88  GLN 88  87  87  GLN GLN c . n 
D 3 89  ALA 89  88  88  ALA ALA c . n 
D 3 90  TYR 90  89  89  TYR TYR c . n 
D 3 91  ALA 91  90  90  ALA ALA c . n 
D 3 92  ASP 92  91  91  ASP ASP c . n 
D 3 93  VAL 93  92  92  VAL VAL c . n 
D 3 94  THR 94  93  93  THR THR c . n 
D 3 95  PHE 95  94  94  PHE PHE c . n 
D 3 96  SER 96  95  95  SER SER c . n 
D 3 97  PHE 97  96  96  PHE PHE c . n 
D 3 98  THR 98  97  97  THR THR c . n 
D 3 99  GLN 99  98  98  GLN GLN c . n 
D 3 100 TYR 100 99  99  TYR TYR c . n 
D 3 101 SER 101 100 100 SER SER c . n 
D 3 102 THR 102 101 101 THR THR c . n 
D 3 103 ASP 103 102 102 ASP ASP c . n 
D 3 104 GLU 104 103 103 GLU GLU c . n 
D 3 105 GLU 105 104 104 GLU GLU c . n 
D 3 106 ARG 106 105 105 ARG ARG c . n 
D 3 107 ALA 107 106 106 ALA ALA c . n 
D 3 108 PHE 108 107 107 PHE PHE c . n 
D 3 109 VAL 109 108 108 VAL VAL c . n 
D 3 110 ARG 110 109 109 ARG ARG c . n 
D 3 111 THR 111 110 110 THR THR c . n 
D 3 112 GLU 112 111 111 GLU GLU c . n 
D 3 113 LEU 113 112 112 LEU LEU c . n 
D 3 114 ALA 114 113 113 ALA ALA c . n 
D 3 115 ALA 115 114 114 ALA ALA c . n 
D 3 116 LEU 116 115 115 LEU LEU c . n 
D 3 117 LEU 117 116 116 LEU LEU c . n 
D 3 118 ALA 118 117 117 ALA ALA c . n 
D 3 119 SER 119 118 118 SER SER c . n 
D 3 120 PRO 120 119 119 PRO PRO c . n 
D 3 121 LEU 121 120 120 LEU LEU c . n 
D 3 122 LEU 122 121 121 LEU LEU c . n 
D 3 123 ILE 123 122 122 ILE ILE c . n 
D 3 124 ASP 124 123 123 ASP ASP c . n 
D 3 125 ALA 125 124 124 ALA ALA c . n 
D 3 126 ILE 126 125 125 ILE ILE c . n 
D 3 127 ASP 127 126 126 ASP ASP c . n 
D 3 128 GLN 128 127 127 GLN GLN c . n 
D 3 129 LEU 129 128 128 LEU LEU c . n 
D 3 130 ASN 130 129 129 ASN ASN c . n 
D 3 131 PRO 131 130 130 PRO PRO c . n 
D 3 132 ALA 132 131 131 ALA ALA c . n 
D 3 133 TYR 133 132 132 TYR TYR c . n 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8W5V 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8W5V 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8W5V 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 8W5V 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.002 ? 3654 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.525 ? 4969 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 4.183 ? 501  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.041 ? 574  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.005 ? 639  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8W5V 
_struct.title                        'Cryo-EM structure of QbN10K-Ab40' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8W5V 
_struct_keywords.text            'Qb, Antibody, cryo-EM, IMMUNE SYSTEM' 
_struct_keywords.pdbx_keywords   'IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 3 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 8W5V     8W5V   ? 1 ? 1 
2 PDB 8W5V     8W5V   ? 2 ? 1 
3 UNP A1_BPQBE Q8LTE1 ? 3 
;MAKLETVTLGNIGKDGKQTLVLNPRGVNPTNGVASLSQAGAVPALEKRVTVSVSQPSRNRKNYKVQVKIQNPTACTANGS
CDPSVTRQAYADVTFSFTQYSTDEERAFVRTELAALLASPLLIDAIDQLNPAY
;
1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8W5V L 1 ? 115 ? 8W5V   1 ? 115 ? 1 115 
2 2 8W5V H 1 ? 121 ? 8W5V   1 ? 121 ? 1 121 
3 3 8W5V C 1 ? 133 ? Q8LTE1 1 ? 133 ? 0 132 
4 3 8W5V c 1 ? 133 ? Q8LTE1 1 ? 133 ? 0 132 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
3 8W5V LYS C 11 ? UNP Q8LTE1 ASN 11 conflict 10 1 
4 8W5V LYS c 11 ? UNP Q8LTE1 ASN 11 conflict 10 2 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 AA1 THR C 102 ? LEU C 117 ? THR C 101 LEU C 116 1 ? 16 
HELX_P HELX_P2 AA2 SER C 119 ? GLN C 128 ? SER C 118 GLN C 127 1 ? 10 
HELX_P HELX_P3 AA3 THR D 102 ? LEU D 117 ? THR c 101 LEU c 116 1 ? 16 
HELX_P HELX_P4 AA4 SER D 119 ? GLN D 128 ? SER c 118 GLN c 127 1 ? 10 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_conn.id                            disulf1 
_struct_conn.conn_type_id                  disulf 
_struct_conn.pdbx_leaving_atom_flag        ? 
_struct_conn.pdbx_PDB_id                   ? 
_struct_conn.ptnr1_label_asym_id           B 
_struct_conn.ptnr1_label_comp_id           CYS 
_struct_conn.ptnr1_label_seq_id            25 
_struct_conn.ptnr1_label_atom_id           SG 
_struct_conn.pdbx_ptnr1_label_alt_id       ? 
_struct_conn.pdbx_ptnr1_PDB_ins_code       ? 
_struct_conn.pdbx_ptnr1_standard_comp_id   ? 
_struct_conn.ptnr1_symmetry                1_555 
_struct_conn.ptnr2_label_asym_id           B 
_struct_conn.ptnr2_label_comp_id           CYS 
_struct_conn.ptnr2_label_seq_id            99 
_struct_conn.ptnr2_label_atom_id           SG 
_struct_conn.pdbx_ptnr2_label_alt_id       ? 
_struct_conn.pdbx_ptnr2_PDB_ins_code       ? 
_struct_conn.ptnr1_auth_asym_id            H 
_struct_conn.ptnr1_auth_comp_id            CYS 
_struct_conn.ptnr1_auth_seq_id             25 
_struct_conn.ptnr2_auth_asym_id            H 
_struct_conn.ptnr2_auth_comp_id            CYS 
_struct_conn.ptnr2_auth_seq_id             99 
_struct_conn.ptnr2_symmetry                1_555 
_struct_conn.pdbx_ptnr3_label_atom_id      ? 
_struct_conn.pdbx_ptnr3_label_seq_id       ? 
_struct_conn.pdbx_ptnr3_label_comp_id      ? 
_struct_conn.pdbx_ptnr3_label_asym_id      ? 
_struct_conn.pdbx_ptnr3_label_alt_id       ? 
_struct_conn.pdbx_ptnr3_PDB_ins_code       ? 
_struct_conn.details                       ? 
_struct_conn.pdbx_dist_value               2.032 
_struct_conn.pdbx_value_order              ? 
_struct_conn.pdbx_role                     ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
_pdbx_modification_feature.ordinal                            1 
_pdbx_modification_feature.label_comp_id                      CYS 
_pdbx_modification_feature.label_asym_id                      B 
_pdbx_modification_feature.label_seq_id                       25 
_pdbx_modification_feature.label_alt_id                       ? 
_pdbx_modification_feature.modified_residue_label_comp_id     CYS 
_pdbx_modification_feature.modified_residue_label_asym_id     B 
_pdbx_modification_feature.modified_residue_label_seq_id      99 
_pdbx_modification_feature.modified_residue_label_alt_id      ? 
_pdbx_modification_feature.auth_comp_id                       CYS 
_pdbx_modification_feature.auth_asym_id                       H 
_pdbx_modification_feature.auth_seq_id                        25 
_pdbx_modification_feature.PDB_ins_code                       ? 
_pdbx_modification_feature.symmetry                           1_555 
_pdbx_modification_feature.modified_residue_auth_comp_id      CYS 
_pdbx_modification_feature.modified_residue_auth_asym_id      H 
_pdbx_modification_feature.modified_residue_auth_seq_id       99 
_pdbx_modification_feature.modified_residue_PDB_ins_code      ? 
_pdbx_modification_feature.modified_residue_symmetry          1_555 
_pdbx_modification_feature.comp_id_linking_atom               SG 
_pdbx_modification_feature.modified_residue_id_linking_atom   SG 
_pdbx_modification_feature.modified_residue_id                . 
_pdbx_modification_feature.ref_pcm_id                         . 
_pdbx_modification_feature.ref_comp_id                        . 
_pdbx_modification_feature.type                               None 
_pdbx_modification_feature.category                           'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 3  ? 
AA2 ? 4  ? 
AA3 ? 4  ? 
AA4 ? 5  ? 
AA5 ? 12 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1  2  ? anti-parallel 
AA1 2  3  ? anti-parallel 
AA2 1  2  ? anti-parallel 
AA2 2  3  ? anti-parallel 
AA2 3  4  ? anti-parallel 
AA3 1  2  ? anti-parallel 
AA3 2  3  ? anti-parallel 
AA3 3  4  ? anti-parallel 
AA4 1  2  ? anti-parallel 
AA4 2  3  ? anti-parallel 
AA4 3  4  ? anti-parallel 
AA4 4  5  ? anti-parallel 
AA5 1  2  ? anti-parallel 
AA5 2  3  ? anti-parallel 
AA5 3  4  ? anti-parallel 
AA5 4  5  ? anti-parallel 
AA5 5  6  ? anti-parallel 
AA5 6  7  ? anti-parallel 
AA5 7  8  ? anti-parallel 
AA5 8  9  ? anti-parallel 
AA5 9  10 ? anti-parallel 
AA5 10 11 ? anti-parallel 
AA5 11 12 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1  THR A 23  ? LYS A 27  ? THR L 23  LYS L 27  
AA1 2  ASP A 79  ? ILE A 84  ? ASP L 79  ILE L 84  
AA1 3  PHE A 71  ? SER A 74  ? PHE L 71  SER L 74  
AA2 1  THR A 62  ? ARG A 63  ? THR L 62  ARG L 63  
AA2 2  LYS A 54  ? TYR A 58  ? LYS L 54  TYR L 58  
AA2 3  LEU A 42  ? GLN A 47  ? LEU L 42  GLN L 47  
AA2 4  ILE A 94  ? GLN A 99  ? ILE L 94  GLN L 99  
AA3 1  GLN B 6   ? GLN B 9   ? GLN H 6   GLN H 9   
AA3 2  VAL B 21  ? SER B 28  ? VAL H 21  SER H 28  
AA3 3  THR B 81  ? LEU B 86  ? THR H 81  LEU H 86  
AA3 4  THR B 72  ? ASP B 76  ? THR H 72  ASP H 76  
AA4 1  ILE B 62  ? TYR B 63  ? ILE H 62  TYR H 63  
AA4 2  GLY B 52  ? PHE B 54  ? GLY H 52  PHE H 54  
AA4 3  SER B 36  ? HIS B 38  ? SER H 36  HIS H 38  
AA4 4  SER B 100 ? GLY B 102 ? SER H 100 GLY H 102 
AA4 5  PHE B 108 ? TRP B 111 ? PHE H 108 TRP H 111 
AA5 1  VAL C 7   ? ILE C 12  ? VAL C 6   ILE C 11  
AA5 2  GLN C 18  ? VAL C 27  ? GLN C 17  VAL C 26  
AA5 3  ALA C 34  ? SER C 37  ? ALA C 33  SER C 36  
AA5 4  ARG C 48  ? VAL C 53  ? ARG C 47  VAL C 52  
AA5 5  VAL C 65  ? CYS C 75  ? VAL C 64  CYS C 74  
AA5 6  SER C 84  ? PHE C 95  ? SER C 83  PHE C 94  
AA5 7  SER D 84  ? PHE D 95  ? SER c 83  PHE c 94  
AA5 8  VAL D 65  ? CYS D 75  ? VAL c 64  CYS c 74  
AA5 9  ARG D 48  ? VAL D 53  ? ARG c 47  VAL c 52  
AA5 10 VAL D 33  ? SER D 37  ? VAL c 32  SER c 36  
AA5 11 GLN D 18  ? ASN D 28  ? GLN c 17  ASN c 27  
AA5 12 VAL D 7   ? ILE D 12  ? VAL c 6   ILE c 11  
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1  2  N LEU A 24  ? N LEU L 24  O LEU A 82  ? O LEU L 82  
AA1 2  3  O THR A 83  ? O THR L 83  N THR A 72  ? N THR L 72  
AA2 1  2  O THR A 62  ? O THR L 62  N TYR A 58  ? N TYR L 58  
AA2 2  3  O LYS A 54  ? O LYS L 54  N GLN A 46  ? N GLN L 46  
AA2 3  4  N TYR A 45  ? N TYR L 45  O TYR A 96  ? O TYR L 96  
AA3 1  2  N GLN B 8   ? N GLN H 8   O LYS B 26  ? O LYS H 26  
AA3 2  3  N CYS B 25  ? N CYS H 25  O ALA B 82  ? O ALA H 82  
AA3 3  4  O THR B 81  ? O THR H 81  N ASP B 76  ? N ASP H 76  
AA4 1  2  O ILE B 62  ? O ILE H 62  N TYR B 53  ? N TYR H 53  
AA4 2  3  O PHE B 54  ? O PHE H 54  N LEU B 37  ? N LEU H 37  
AA4 3  4  N SER B 36  ? N SER H 36  O GLY B 102 ? O GLY H 102 
AA4 4  5  N THR B 101 ? N THR H 101 O ASP B 109 ? O ASP H 109 
AA5 1  2  N LEU C 9   ? N LEU C 8   O LEU C 20  ? O LEU C 19  
AA5 2  3  N ASN C 23  ? N ASN C 22  O SER C 37  ? O SER C 36  
AA5 3  4  N ALA C 34  ? N ALA C 33  O VAL C 51  ? O VAL C 50  
AA5 4  5  N SER C 52  ? N SER C 51  O GLN C 66  ? O GLN C 65  
AA5 5  6  N VAL C 65  ? N VAL C 64  O PHE C 95  ? O PHE C 94  
AA5 6  7  N THR C 94  ? N THR C 93  O ASP D 92  ? O ASP c 91  
AA5 7  8  O VAL D 93  ? O VAL c 92  N VAL D 67  ? N VAL c 66  
AA5 8  9  O GLN D 66  ? O GLN c 65  N SER D 52  ? N SER c 51  
AA5 9  10 O VAL D 51  ? O VAL c 50  N ALA D 34  ? N ALA c 33  
AA5 10 11 O SER D 37  ? O SER c 36  N ASN D 23  ? N ASN c 22  
AA5 11 12 O LEU D 22  ? O LEU c 21  N VAL D 7   ? N VAL c 6   
# 
_pdbx_entry_details.entry_id                   8W5V 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_close_contact.id               1 
_pdbx_validate_close_contact.PDB_model_num    1 
_pdbx_validate_close_contact.auth_atom_id_1   O 
_pdbx_validate_close_contact.auth_asym_id_1   c 
_pdbx_validate_close_contact.auth_comp_id_1   LEU 
_pdbx_validate_close_contact.auth_seq_id_1    8 
_pdbx_validate_close_contact.PDB_ins_code_1   ? 
_pdbx_validate_close_contact.label_alt_id_1   ? 
_pdbx_validate_close_contact.auth_atom_id_2   OG1 
_pdbx_validate_close_contact.auth_asym_id_2   c 
_pdbx_validate_close_contact.auth_comp_id_2   THR 
_pdbx_validate_close_contact.auth_seq_id_2    18 
_pdbx_validate_close_contact.PDB_ins_code_2   ? 
_pdbx_validate_close_contact.label_alt_id_2   ? 
_pdbx_validate_close_contact.dist             2.16 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ALA L 60  ? ? 68.82   -5.18   
2  1 SER L 86  ? ? 64.74   156.13  
3  1 ASP L 91  ? ? -140.06 30.47   
4  1 ALA L 93  ? ? 77.44   175.45  
5  1 ARG L 102 ? ? 57.13   -96.01  
6  1 SER H 17  ? ? 53.72   -150.03 
7  1 SER H 43  ? ? 54.73   -136.40 
8  1 SER H 47  ? ? 69.19   159.89  
9  1 ILE H 51  ? ? -121.95 -59.32  
10 1 LYS H 66  ? ? 47.45   24.79   
11 1 ALA C 40  ? ? 67.45   -5.59   
12 1 ALA c 40  ? ? 67.85   -5.12   
13 1 TYR c 99  ? ? -93.56  31.12   
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8W5V 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8W5V 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.4 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               802733 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Complex of QbN10K-Ab40' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1,2,3 
# 
_em_imaging.entry_id                        8W5V 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1200 
_em_imaging.nominal_defocus_max             1600 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8W5V 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8W5V 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 L VAL 1   ? A VAL 1   
2  1 Y 1 L HIS 2   ? A HIS 2   
3  1 Y 1 L SER 3   ? A SER 3   
4  1 Y 1 L ASP 4   ? A ASP 4   
5  1 Y 1 L LYS 111 ? A LYS 111 
6  1 Y 1 L LEU 112 ? A LEU 112 
7  1 Y 1 L GLU 113 ? A GLU 113 
8  1 Y 1 L ILE 114 ? A ILE 114 
9  1 Y 1 L LYS 115 ? A LYS 115 
10 1 Y 1 H VAL 1   ? B VAL 1   
11 1 Y 1 H HIS 2   ? B HIS 2   
12 1 Y 1 H SER 3   ? B SER 3   
13 1 Y 1 H GLU 4   ? B GLU 4   
14 1 Y 1 H THR 118 ? B THR 118 
15 1 Y 1 H VAL 119 ? B VAL 119 
16 1 Y 1 H SER 120 ? B SER 120 
17 1 Y 1 H SER 121 ? B SER 121 
18 1 Y 1 C MET 0   ? C MET 1   
19 1 Y 1 C SER 56  ? C SER 57  
20 1 Y 1 C ARG 57  ? C ARG 58  
21 1 Y 1 C ASN 58  ? C ASN 59  
22 1 Y 1 C ARG 59  ? C ARG 60  
23 1 Y 1 C LYS 60  ? C LYS 61  
24 1 Y 1 C TYR 132 ? C TYR 133 
25 1 Y 1 c MET 0   ? D MET 1   
26 1 Y 1 c SER 56  ? D SER 57  
27 1 Y 1 c ARG 57  ? D ARG 58  
28 1 Y 1 c ASN 58  ? D ASN 59  
29 1 Y 1 c ARG 59  ? D ARG 60  
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-08-27 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8W5V 
_em_admin.last_update        2025-02-26 
_em_admin.map_release_date   2025-02-26 
_em_admin.title              'Cryo-EM structure of QbN10K-Ab40' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          10088 
_em_entity_assembly_naturalsource.organism             Mus 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         60 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K2 SUMMIT (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ?      ?            
'MODEL REFINEMENT'         ? 2  ? ? ? PHENIX 1.19.2_4158: 
'IMAGE ACQUISITION'        ? 3  ? ? 1 ?      ?            
MASKING                    ? 4  ? ? ? ?      ?            
'CTF CORRECTION'           ? 5  1 ? ? ?      ?            
'LAYERLINE INDEXING'       ? 6  ? ? ? ?      ?            
'DIFFRACTION INDEXING'     ? 7  ? ? ? ?      ?            
'MODEL FITTING'            ? 8  ? ? ? ?      ?            
OTHER                      ? 9  ? ? ? ?      ?            
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ?      ?            
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ?      ?            
CLASSIFICATION             ? 12 1 ? ? ?      ?            
RECONSTRUCTION             ? 13 1 ? ? ?      ?            
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Natural Science Foundation of China (NSFC)' China 81991495    1 
'National Natural Science Foundation of China (NSFC)' China 32241029    2 
'Chinese Academy of Sciences'                         China XDB29050600 3 
'Chinese Academy of Sciences'                         China XDB37010100 4 
# 
_atom_sites.entry_id                    8W5V 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . ILE A 1 5   ? 108.295 102.279 131.537 1.00 86.15  ? 5   ILE L N   1 
ATOM 2    C CA  . ILE A 1 5   ? 109.459 103.106 131.830 1.00 86.15  ? 5   ILE L CA  1 
ATOM 3    C C   . ILE A 1 5   ? 109.216 103.896 133.110 1.00 86.15  ? 5   ILE L C   1 
ATOM 4    O O   . ILE A 1 5   ? 108.489 104.888 133.110 1.00 86.15  ? 5   ILE L O   1 
ATOM 5    C CB  . ILE A 1 5   ? 109.798 104.051 130.656 1.00 86.15  ? 5   ILE L CB  1 
ATOM 6    C CG1 . ILE A 1 5   ? 110.171 103.256 129.400 1.00 86.15  ? 5   ILE L CG1 1 
ATOM 7    C CG2 . ILE A 1 5   ? 110.932 104.990 131.035 1.00 86.15  ? 5   ILE L CG2 1 
ATOM 8    C CD1 . ILE A 1 5   ? 108.996 102.898 128.509 1.00 86.15  ? 5   ILE L CD1 1 
ATOM 9    N N   . VAL A 1 6   ? 109.824 103.447 134.204 1.00 88.57  ? 6   VAL L N   1 
ATOM 10   C CA  . VAL A 1 6   ? 109.683 104.123 135.488 1.00 88.57  ? 6   VAL L CA  1 
ATOM 11   C C   . VAL A 1 6   ? 110.548 105.375 135.487 1.00 88.57  ? 6   VAL L C   1 
ATOM 12   O O   . VAL A 1 6   ? 111.690 105.358 135.013 1.00 88.57  ? 6   VAL L O   1 
ATOM 13   C CB  . VAL A 1 6   ? 110.058 103.183 136.645 1.00 88.57  ? 6   VAL L CB  1 
ATOM 14   C CG1 . VAL A 1 6   ? 108.966 102.150 136.860 1.00 88.57  ? 6   VAL L CG1 1 
ATOM 15   C CG2 . VAL A 1 6   ? 111.387 102.499 136.369 1.00 88.57  ? 6   VAL L CG2 1 
ATOM 16   N N   . MET A 1 7   ? 110.001 106.470 136.010 1.00 85.68  ? 7   MET L N   1 
ATOM 17   C CA  . MET A 1 7   ? 110.676 107.765 136.033 1.00 85.68  ? 7   MET L CA  1 
ATOM 18   C C   . MET A 1 7   ? 110.831 108.181 137.494 1.00 85.68  ? 7   MET L C   1 
ATOM 19   O O   . MET A 1 7   ? 109.982 108.886 138.044 1.00 85.68  ? 7   MET L O   1 
ATOM 20   C CB  . MET A 1 7   ? 109.890 108.797 135.226 1.00 85.68  ? 7   MET L CB  1 
ATOM 21   C CG  . MET A 1 7   ? 110.064 108.661 133.721 1.00 85.68  ? 7   MET L CG  1 
ATOM 22   S SD  . MET A 1 7   ? 111.516 109.505 133.072 1.00 85.68  ? 7   MET L SD  1 
ATOM 23   C CE  . MET A 1 7   ? 111.434 111.044 133.976 1.00 85.68  ? 7   MET L CE  1 
ATOM 24   N N   . SER A 1 8   ? 111.918 107.737 138.121 1.00 89.90  ? 8   SER L N   1 
ATOM 25   C CA  . SER A 1 8   ? 112.172 108.076 139.514 1.00 89.90  ? 8   SER L CA  1 
ATOM 26   C C   . SER A 1 8   ? 112.580 109.538 139.639 1.00 89.90  ? 8   SER L C   1 
ATOM 27   O O   . SER A 1 8   ? 113.110 110.134 138.698 1.00 89.90  ? 8   SER L O   1 
ATOM 28   C CB  . SER A 1 8   ? 113.261 107.173 140.091 1.00 89.90  ? 8   SER L CB  1 
ATOM 29   O OG  . SER A 1 8   ? 113.580 107.545 141.420 1.00 89.90  ? 8   SER L OG  1 
ATOM 30   N N   . GLN A 1 9   ? 112.331 110.118 140.811 1.00 87.44  ? 9   GLN L N   1 
ATOM 31   C CA  . GLN A 1 9   ? 112.572 111.534 141.043 1.00 87.44  ? 9   GLN L CA  1 
ATOM 32   C C   . GLN A 1 9   ? 113.139 111.745 142.444 1.00 87.44  ? 9   GLN L C   1 
ATOM 33   O O   . GLN A 1 9   ? 113.447 110.796 143.171 1.00 87.44  ? 9   GLN L O   1 
ATOM 34   C CB  . GLN A 1 9   ? 111.284 112.347 140.854 1.00 87.44  ? 9   GLN L CB  1 
ATOM 35   C CG  . GLN A 1 9   ? 111.490 113.702 140.197 1.00 87.44  ? 9   GLN L CG  1 
ATOM 36   C CD  . GLN A 1 9   ? 110.204 114.493 140.080 1.00 87.44  ? 9   GLN L CD  1 
ATOM 37   O OE1 . GLN A 1 9   ? 109.114 113.925 140.052 1.00 87.44  ? 9   GLN L OE1 1 
ATOM 38   N NE2 . GLN A 1 9   ? 110.324 115.813 140.018 1.00 87.44  ? 9   GLN L NE2 1 
ATOM 39   N N   . SER A 1 10  ? 113.274 113.021 142.810 1.00 97.58  ? 10  SER L N   1 
ATOM 40   C CA  . SER A 1 10  ? 113.723 113.413 144.134 1.00 97.58  ? 10  SER L CA  1 
ATOM 41   C C   . SER A 1 10  ? 112.664 113.043 145.173 1.00 97.58  ? 10  SER L C   1 
ATOM 42   O O   . SER A 1 10  ? 111.504 112.801 144.827 1.00 97.58  ? 10  SER L O   1 
ATOM 43   C CB  . SER A 1 10  ? 114.004 114.918 144.152 1.00 97.58  ? 10  SER L CB  1 
ATOM 44   O OG  . SER A 1 10  ? 114.179 115.430 145.461 1.00 97.58  ? 10  SER L OG  1 
ATOM 45   N N   . PRO A 1 11  ? 113.049 112.961 146.462 1.00 100.19 ? 11  PRO L N   1 
ATOM 46   C CA  . PRO A 1 11  ? 112.056 112.707 147.518 1.00 100.19 ? 11  PRO L CA  1 
ATOM 47   C C   . PRO A 1 11  ? 110.861 113.651 147.482 1.00 100.19 ? 11  PRO L C   1 
ATOM 48   O O   . PRO A 1 11  ? 110.889 114.689 146.814 1.00 100.19 ? 11  PRO L O   1 
ATOM 49   C CB  . PRO A 1 11  ? 112.868 112.877 148.813 1.00 100.19 ? 11  PRO L CB  1 
ATOM 50   C CG  . PRO A 1 11  ? 114.236 113.383 148.380 1.00 100.19 ? 11  PRO L CG  1 
ATOM 51   C CD  . PRO A 1 11  ? 114.415 112.864 146.996 1.00 100.19 ? 11  PRO L CD  1 
ATOM 52   N N   . SER A 1 12  ? 109.811 113.291 148.225 1.00 102.24 ? 12  SER L N   1 
ATOM 53   C CA  . SER A 1 12  ? 108.492 113.880 148.007 1.00 102.24 ? 12  SER L CA  1 
ATOM 54   C C   . SER A 1 12  ? 108.480 115.383 148.262 1.00 102.24 ? 12  SER L C   1 
ATOM 55   O O   . SER A 1 12  ? 107.856 116.137 147.508 1.00 102.24 ? 12  SER L O   1 
ATOM 56   C CB  . SER A 1 12  ? 107.459 113.185 148.893 1.00 102.24 ? 12  SER L CB  1 
ATOM 57   O OG  . SER A 1 12  ? 107.694 113.465 150.262 1.00 102.24 ? 12  SER L OG  1 
ATOM 58   N N   . SER A 1 13  ? 109.149 115.841 149.317 1.00 107.21 ? 13  SER L N   1 
ATOM 59   C CA  . SER A 1 13  ? 109.018 117.224 149.749 1.00 107.21 ? 13  SER L CA  1 
ATOM 60   C C   . SER A 1 13  ? 110.379 117.835 150.052 1.00 107.21 ? 13  SER L C   1 
ATOM 61   O O   . SER A 1 13  ? 111.349 117.139 150.360 1.00 107.21 ? 13  SER L O   1 
ATOM 62   C CB  . SER A 1 13  ? 108.117 117.336 150.987 1.00 107.21 ? 13  SER L CB  1 
ATOM 63   O OG  . SER A 1 13  ? 108.271 118.595 151.619 1.00 107.21 ? 13  SER L OG  1 
ATOM 64   N N   . LEU A 1 14  ? 110.428 119.162 149.951 1.00 112.38 ? 14  LEU L N   1 
ATOM 65   C CA  . LEU A 1 14  ? 111.559 119.975 150.374 1.00 112.38 ? 14  LEU L CA  1 
ATOM 66   C C   . LEU A 1 14  ? 111.041 121.086 151.281 1.00 112.38 ? 14  LEU L C   1 
ATOM 67   O O   . LEU A 1 14  ? 109.837 121.208 151.522 1.00 112.38 ? 14  LEU L O   1 
ATOM 68   C CB  . LEU A 1 14  ? 112.319 120.552 149.172 1.00 112.38 ? 14  LEU L CB  1 
ATOM 69   C CG  . LEU A 1 14  ? 113.138 119.559 148.346 1.00 112.38 ? 14  LEU L CG  1 
ATOM 70   C CD1 . LEU A 1 14  ? 113.783 120.254 147.159 1.00 112.38 ? 14  LEU L CD1 1 
ATOM 71   C CD2 . LEU A 1 14  ? 114.188 118.884 149.212 1.00 112.38 ? 14  LEU L CD2 1 
ATOM 72   N N   . ALA A 1 15  ? 111.961 121.908 151.794 1.00 117.51 ? 15  ALA L N   1 
ATOM 73   C CA  . ALA A 1 15  ? 111.580 122.957 152.732 1.00 117.51 ? 15  ALA L CA  1 
ATOM 74   C C   . ALA A 1 15  ? 112.304 124.269 152.447 1.00 117.51 ? 15  ALA L C   1 
ATOM 75   O O   . ALA A 1 15  ? 112.602 125.029 153.375 1.00 117.51 ? 15  ALA L O   1 
ATOM 76   C CB  . ALA A 1 15  ? 111.839 122.523 154.176 1.00 117.51 ? 15  ALA L CB  1 
ATOM 77   N N   . VAL A 1 16  ? 112.597 124.553 151.178 1.00 123.75 ? 16  VAL L N   1 
ATOM 78   C CA  . VAL A 1 16  ? 113.230 125.817 150.828 1.00 123.75 ? 16  VAL L CA  1 
ATOM 79   C C   . VAL A 1 16  ? 112.226 126.951 150.981 1.00 123.75 ? 16  VAL L C   1 
ATOM 80   O O   . VAL A 1 16  ? 111.058 126.832 150.585 1.00 123.75 ? 16  VAL L O   1 
ATOM 81   C CB  . VAL A 1 16  ? 113.801 125.757 149.401 1.00 123.75 ? 16  VAL L CB  1 
ATOM 82   C CG1 . VAL A 1 16  ? 115.073 124.926 149.383 1.00 123.75 ? 16  VAL L CG1 1 
ATOM 83   C CG2 . VAL A 1 16  ? 112.773 125.180 148.441 1.00 123.75 ? 16  VAL L CG2 1 
ATOM 84   N N   . SER A 1 17  ? 112.674 128.063 151.567 1.00 129.05 ? 17  SER L N   1 
ATOM 85   C CA  . SER A 1 17  ? 111.790 129.171 151.907 1.00 129.05 ? 17  SER L CA  1 
ATOM 86   C C   . SER A 1 17  ? 111.946 130.359 150.967 1.00 129.05 ? 17  SER L C   1 
ATOM 87   O O   . SER A 1 17  ? 110.970 130.777 150.337 1.00 129.05 ? 17  SER L O   1 
ATOM 88   C CB  . SER A 1 17  ? 112.035 129.606 153.358 1.00 129.05 ? 17  SER L CB  1 
ATOM 89   O OG  . SER A 1 17  ? 113.083 130.556 153.434 1.00 129.05 ? 17  SER L OG  1 
ATOM 90   N N   . ILE A 1 18  ? 113.151 130.918 150.846 1.00 131.80 ? 18  ILE L N   1 
ATOM 91   C CA  . ILE A 1 18  ? 113.358 132.118 150.043 1.00 131.80 ? 18  ILE L CA  1 
ATOM 92   C C   . ILE A 1 18  ? 114.846 132.259 149.761 1.00 131.80 ? 18  ILE L C   1 
ATOM 93   O O   . ILE A 1 18  ? 115.688 131.896 150.588 1.00 131.80 ? 18  ILE L O   1 
ATOM 94   C CB  . ILE A 1 18  ? 112.783 133.373 150.752 1.00 131.80 ? 18  ILE L CB  1 
ATOM 95   C CG1 . ILE A 1 18  ? 112.717 134.562 149.791 1.00 131.80 ? 18  ILE L CG1 1 
ATOM 96   C CG2 . ILE A 1 18  ? 113.590 133.718 151.996 1.00 131.80 ? 18  ILE L CG2 1 
ATOM 97   C CD1 . ILE A 1 18  ? 111.743 134.374 148.655 1.00 131.80 ? 18  ILE L CD1 1 
ATOM 98   N N   . GLY A 1 19  ? 115.169 132.766 148.572 1.00 131.26 ? 19  GLY L N   1 
ATOM 99   C CA  . GLY A 1 19  ? 116.538 133.090 148.216 1.00 131.26 ? 19  GLY L CA  1 
ATOM 100  C C   . GLY A 1 19  ? 117.422 131.906 147.881 1.00 131.26 ? 19  GLY L C   1 
ATOM 101  O O   . GLY A 1 19  ? 118.437 132.059 147.195 1.00 131.26 ? 19  GLY L O   1 
ATOM 102  N N   . GLU A 1 20  ? 117.050 130.720 148.356 1.00 132.54 ? 20  GLU L N   1 
ATOM 103  C CA  . GLU A 1 20  ? 117.890 129.545 148.180 1.00 132.54 ? 20  GLU L CA  1 
ATOM 104  C C   . GLU A 1 20  ? 117.905 129.092 146.724 1.00 132.54 ? 20  GLU L C   1 
ATOM 105  O O   . GLU A 1 20  ? 116.883 129.127 146.032 1.00 132.54 ? 20  GLU L O   1 
ATOM 106  C CB  . GLU A 1 20  ? 117.404 128.409 149.079 1.00 132.54 ? 20  GLU L CB  1 
ATOM 107  C CG  . GLU A 1 20  ? 117.971 128.457 150.488 1.00 132.54 ? 20  GLU L CG  1 
ATOM 108  C CD  . GLU A 1 20  ? 116.952 128.066 151.539 1.00 132.54 ? 20  GLU L CD  1 
ATOM 109  O OE1 . GLU A 1 20  ? 115.812 127.726 151.163 1.00 132.54 ? 20  GLU L OE1 1 
ATOM 110  O OE2 . GLU A 1 20  ? 117.291 128.097 152.741 1.00 132.54 ? 20  GLU L OE2 1 
ATOM 111  N N   . LYS A 1 21  ? 119.080 128.664 146.264 1.00 125.77 ? 21  LYS L N   1 
ATOM 112  C CA  . LYS A 1 21  ? 119.253 128.154 144.903 1.00 125.77 ? 21  LYS L CA  1 
ATOM 113  C C   . LYS A 1 21  ? 118.901 126.666 144.873 1.00 125.77 ? 21  LYS L C   1 
ATOM 114  O O   . LYS A 1 21  ? 119.747 125.788 144.698 1.00 125.77 ? 21  LYS L O   1 
ATOM 115  C CB  . LYS A 1 21  ? 120.677 128.406 144.422 1.00 125.77 ? 21  LYS L CB  1 
ATOM 116  C CG  . LYS A 1 21  ? 120.864 128.303 142.917 1.00 125.77 ? 21  LYS L CG  1 
ATOM 117  C CD  . LYS A 1 21  ? 120.253 129.496 142.203 1.00 125.77 ? 21  LYS L CD  1 
ATOM 118  C CE  . LYS A 1 21  ? 120.751 130.806 142.789 1.00 125.77 ? 21  LYS L CE  1 
ATOM 119  N NZ  . LYS A 1 21  ? 120.370 131.972 141.946 1.00 125.77 ? 21  LYS L NZ  1 
ATOM 120  N N   . VAL A 1 22  ? 117.613 126.395 145.055 1.00 116.40 ? 22  VAL L N   1 
ATOM 121  C CA  . VAL A 1 22  ? 117.125 125.023 145.115 1.00 116.40 ? 22  VAL L CA  1 
ATOM 122  C C   . VAL A 1 22  ? 117.154 124.409 143.722 1.00 116.40 ? 22  VAL L C   1 
ATOM 123  O O   . VAL A 1 22  ? 116.865 125.075 142.720 1.00 116.40 ? 22  VAL L O   1 
ATOM 124  C CB  . VAL A 1 22  ? 115.714 124.975 145.732 1.00 116.40 ? 22  VAL L CB  1 
ATOM 125  C CG1 . VAL A 1 22  ? 114.707 125.691 144.848 1.00 116.40 ? 22  VAL L CG1 1 
ATOM 126  C CG2 . VAL A 1 22  ? 115.288 123.533 145.976 1.00 116.40 ? 22  VAL L CG2 1 
ATOM 127  N N   . THR A 1 23  ? 117.535 123.135 143.654 1.00 108.35 ? 23  THR L N   1 
ATOM 128  C CA  . THR A 1 23  ? 117.582 122.388 142.407 1.00 108.35 ? 23  THR L CA  1 
ATOM 129  C C   . THR A 1 23  ? 116.825 121.079 142.573 1.00 108.35 ? 23  THR L C   1 
ATOM 130  O O   . THR A 1 23  ? 116.833 120.470 143.646 1.00 108.35 ? 23  THR L O   1 
ATOM 131  C CB  . THR A 1 23  ? 119.024 122.091 141.965 1.00 108.35 ? 23  THR L CB  1 
ATOM 132  O OG1 . THR A 1 23  ? 119.583 121.072 142.804 1.00 108.35 ? 23  THR L OG1 1 
ATOM 133  C CG2 . THR A 1 23  ? 119.886 123.341 142.049 1.00 108.35 ? 23  THR L CG2 1 
ATOM 134  N N   . LEU A 1 24  ? 116.172 120.650 141.498 1.00 95.76  ? 24  LEU L N   1 
ATOM 135  C CA  . LEU A 1 24  ? 115.410 119.410 141.475 1.00 95.76  ? 24  LEU L CA  1 
ATOM 136  C C   . LEU A 1 24  ? 116.071 118.435 140.512 1.00 95.76  ? 24  LEU L C   1 
ATOM 137  O O   . LEU A 1 24  ? 116.375 118.796 139.370 1.00 95.76  ? 24  LEU L O   1 
ATOM 138  C CB  . LEU A 1 24  ? 113.960 119.666 141.062 1.00 95.76  ? 24  LEU L CB  1 
ATOM 139  C CG  . LEU A 1 24  ? 113.063 120.300 142.125 1.00 95.76  ? 24  LEU L CG  1 
ATOM 140  C CD1 . LEU A 1 24  ? 112.030 121.212 141.484 1.00 95.76  ? 24  LEU L CD1 1 
ATOM 141  C CD2 . LEU A 1 24  ? 112.390 119.227 142.963 1.00 95.76  ? 24  LEU L CD2 1 
ATOM 142  N N   . THR A 1 25  ? 116.291 117.208 140.971 1.00 93.31  ? 25  THR L N   1 
ATOM 143  C CA  . THR A 1 25  ? 116.968 116.188 140.186 1.00 93.31  ? 25  THR L CA  1 
ATOM 144  C C   . THR A 1 25  ? 116.004 115.065 139.828 1.00 93.31  ? 25  THR L C   1 
ATOM 145  O O   . THR A 1 25  ? 115.000 114.841 140.511 1.00 93.31  ? 25  THR L O   1 
ATOM 146  C CB  . THR A 1 25  ? 118.173 115.616 140.942 1.00 93.31  ? 25  THR L CB  1 
ATOM 147  O OG1 . THR A 1 25  ? 118.912 114.744 140.078 1.00 93.31  ? 25  THR L OG1 1 
ATOM 148  C CG2 . THR A 1 25  ? 117.721 114.844 142.172 1.00 93.31  ? 25  THR L CG2 1 
ATOM 149  N N   . CYS A 1 26  ? 116.315 114.369 138.738 1.00 89.09  ? 26  CYS L N   1 
ATOM 150  C CA  . CYS A 1 26  ? 115.495 113.268 138.258 1.00 89.09  ? 26  CYS L CA  1 
ATOM 151  C C   . CYS A 1 26  ? 116.385 112.225 137.600 1.00 89.09  ? 26  CYS L C   1 
ATOM 152  O O   . CYS A 1 26  ? 117.473 112.535 137.110 1.00 89.09  ? 26  CYS L O   1 
ATOM 153  C CB  . CYS A 1 26  ? 114.430 113.751 137.268 1.00 89.09  ? 26  CYS L CB  1 
ATOM 154  S SG  . CYS A 1 26  ? 113.652 112.429 136.325 1.00 89.09  ? 26  CYS L SG  1 
ATOM 155  N N   . LYS A 1 27  ? 115.910 110.981 137.596 1.00 92.39  ? 27  LYS L N   1 
ATOM 156  C CA  . LYS A 1 27  ? 116.636 109.865 137.008 1.00 92.39  ? 27  LYS L CA  1 
ATOM 157  C C   . LYS A 1 27  ? 115.693 109.041 136.146 1.00 92.39  ? 27  LYS L C   1 
ATOM 158  O O   . LYS A 1 27  ? 114.506 108.912 136.458 1.00 92.39  ? 27  LYS L O   1 
ATOM 159  C CB  . LYS A 1 27  ? 117.269 108.977 138.085 1.00 92.39  ? 27  LYS L CB  1 
ATOM 160  C CG  . LYS A 1 27  ? 118.723 109.302 138.383 1.00 92.39  ? 27  LYS L CG  1 
ATOM 161  C CD  . LYS A 1 27  ? 119.231 108.515 139.581 1.00 92.39  ? 27  LYS L CD  1 
ATOM 162  C CE  . LYS A 1 27  ? 118.410 108.807 140.826 1.00 92.39  ? 27  LYS L CE  1 
ATOM 163  N NZ  . LYS A 1 27  ? 118.590 110.209 141.293 1.00 92.39  ? 27  LYS L NZ  1 
ATOM 164  N N   . SER A 1 28  ? 116.228 108.483 135.066 1.00 89.39  ? 28  SER L N   1 
ATOM 165  C CA  . SER A 1 28  ? 115.462 107.670 134.136 1.00 89.39  ? 28  SER L CA  1 
ATOM 166  C C   . SER A 1 28  ? 115.988 106.241 134.125 1.00 89.39  ? 28  SER L C   1 
ATOM 167  O O   . SER A 1 28  ? 117.167 105.984 134.385 1.00 89.39  ? 28  SER L O   1 
ATOM 168  C CB  . SER A 1 28  ? 115.515 108.259 132.722 1.00 89.39  ? 28  SER L CB  1 
ATOM 169  O OG  . SER A 1 28  ? 114.840 107.424 131.798 1.00 89.39  ? 28  SER L OG  1 
ATOM 170  N N   . SER A 1 29  ? 115.092 105.308 133.818 1.00 89.05  ? 29  SER L N   1 
ATOM 171  C CA  . SER A 1 29  ? 115.424 103.891 133.770 1.00 89.05  ? 29  SER L CA  1 
ATOM 172  C C   . SER A 1 29  ? 115.981 103.454 132.422 1.00 89.05  ? 29  SER L C   1 
ATOM 173  O O   . SER A 1 29  ? 116.381 102.294 132.281 1.00 89.05  ? 29  SER L O   1 
ATOM 174  C CB  . SER A 1 29  ? 114.189 103.050 134.106 1.00 89.05  ? 29  SER L CB  1 
ATOM 175  O OG  . SER A 1 29  ? 114.356 101.709 133.681 1.00 89.05  ? 29  SER L OG  1 
ATOM 176  N N   . GLN A 1 30  ? 116.017 104.346 131.435 1.00 84.38  ? 30  GLN L N   1 
ATOM 177  C CA  . GLN A 1 30  ? 116.488 103.996 130.103 1.00 84.38  ? 30  GLN L CA  1 
ATOM 178  C C   . GLN A 1 30  ? 116.880 105.278 129.385 1.00 84.38  ? 30  GLN L C   1 
ATOM 179  O O   . GLN A 1 30  ? 116.246 106.321 129.567 1.00 84.38  ? 30  GLN L O   1 
ATOM 180  C CB  . GLN A 1 30  ? 115.414 103.222 129.327 1.00 84.38  ? 30  GLN L CB  1 
ATOM 181  C CG  . GLN A 1 30  ? 115.873 102.625 128.007 1.00 84.38  ? 30  GLN L CG  1 
ATOM 182  C CD  . GLN A 1 30  ? 115.680 103.568 126.840 1.00 84.38  ? 30  GLN L CD  1 
ATOM 183  O OE1 . GLN A 1 30  ? 114.769 104.395 126.842 1.00 84.38  ? 30  GLN L OE1 1 
ATOM 184  N NE2 . GLN A 1 30  ? 116.535 103.447 125.832 1.00 84.38  ? 30  GLN L NE2 1 
ATOM 185  N N   . SER A 1 31  ? 117.938 105.191 128.580 1.00 78.36  ? 31  SER L N   1 
ATOM 186  C CA  . SER A 1 31  ? 118.483 106.374 127.926 1.00 78.36  ? 31  SER L CA  1 
ATOM 187  C C   . SER A 1 31  ? 117.447 107.013 127.010 1.00 78.36  ? 31  SER L C   1 
ATOM 188  O O   . SER A 1 31  ? 116.752 106.329 126.255 1.00 78.36  ? 31  SER L O   1 
ATOM 189  C CB  . SER A 1 31  ? 119.736 106.010 127.130 1.00 78.36  ? 31  SER L CB  1 
ATOM 190  O OG  . SER A 1 31  ? 120.323 107.164 126.553 1.00 78.36  ? 31  SER L OG  1 
ATOM 191  N N   . LEU A 1 32  ? 117.357 108.341 127.073 1.00 70.31  ? 32  LEU L N   1 
ATOM 192  C CA  . LEU A 1 32  ? 116.324 109.092 126.374 1.00 70.31  ? 32  LEU L CA  1 
ATOM 193  C C   . LEU A 1 32  ? 116.835 109.750 125.097 1.00 70.31  ? 32  LEU L C   1 
ATOM 194  O O   . LEU A 1 32  ? 116.227 110.712 124.618 1.00 70.31  ? 32  LEU L O   1 
ATOM 195  C CB  . LEU A 1 32  ? 115.722 110.142 127.307 1.00 70.31  ? 32  LEU L CB  1 
ATOM 196  C CG  . LEU A 1 32  ? 114.848 109.575 128.425 1.00 70.31  ? 32  LEU L CG  1 
ATOM 197  C CD1 . LEU A 1 32  ? 114.488 110.654 129.424 1.00 70.31  ? 32  LEU L CD1 1 
ATOM 198  C CD2 . LEU A 1 32  ? 113.596 108.939 127.849 1.00 70.31  ? 32  LEU L CD2 1 
ATOM 199  N N   . LEU A 1 33  ? 117.938 109.255 124.538 1.00 64.73  ? 33  LEU L N   1 
ATOM 200  C CA  . LEU A 1 33  ? 118.443 109.751 123.258 1.00 64.73  ? 33  LEU L CA  1 
ATOM 201  C C   . LEU A 1 33  ? 117.755 109.021 122.102 1.00 64.73  ? 33  LEU L C   1 
ATOM 202  O O   . LEU A 1 33  ? 118.380 108.350 121.283 1.00 64.73  ? 33  LEU L O   1 
ATOM 203  C CB  . LEU A 1 33  ? 119.959 109.597 123.189 1.00 64.73  ? 33  LEU L CB  1 
ATOM 204  C CG  . LEU A 1 33  ? 120.834 110.738 123.714 1.00 64.73  ? 33  LEU L CG  1 
ATOM 205  C CD1 . LEU A 1 33  ? 120.639 111.989 122.874 1.00 64.73  ? 33  LEU L CD1 1 
ATOM 206  C CD2 . LEU A 1 33  ? 120.572 111.027 125.185 1.00 64.73  ? 33  LEU L CD2 1 
ATOM 207  N N   . PHE A 1 34  ? 116.429 109.164 122.058 1.00 59.68  ? 34  PHE L N   1 
ATOM 208  C CA  . PHE A 1 34  ? 115.639 108.462 121.051 1.00 59.68  ? 34  PHE L CA  1 
ATOM 209  C C   . PHE A 1 34  ? 115.898 109.009 119.653 1.00 59.68  ? 34  PHE L C   1 
ATOM 210  O O   . PHE A 1 34  ? 116.042 108.239 118.697 1.00 59.68  ? 34  PHE L O   1 
ATOM 211  C CB  . PHE A 1 34  ? 114.153 108.559 121.390 1.00 59.68  ? 34  PHE L CB  1 
ATOM 212  C CG  . PHE A 1 34  ? 113.720 107.634 122.488 1.00 59.68  ? 34  PHE L CG  1 
ATOM 213  C CD1 . PHE A 1 34  ? 113.722 106.264 122.296 1.00 59.68  ? 34  PHE L CD1 1 
ATOM 214  C CD2 . PHE A 1 34  ? 113.303 108.133 123.709 1.00 59.68  ? 34  PHE L CD2 1 
ATOM 215  C CE1 . PHE A 1 34  ? 113.322 105.409 123.303 1.00 59.68  ? 34  PHE L CE1 1 
ATOM 216  C CE2 . PHE A 1 34  ? 112.901 107.284 124.719 1.00 59.68  ? 34  PHE L CE2 1 
ATOM 217  C CZ  . PHE A 1 34  ? 112.911 105.920 124.516 1.00 59.68  ? 34  PHE L CZ  1 
ATOM 218  N N   . SER A 1 35  ? 115.958 110.330 119.514 1.00 52.78  ? 35  SER L N   1 
ATOM 219  C CA  . SER A 1 35  ? 116.093 110.945 118.203 1.00 52.78  ? 35  SER L CA  1 
ATOM 220  C C   . SER A 1 35  ? 117.448 110.621 117.585 1.00 52.78  ? 35  SER L C   1 
ATOM 221  O O   . SER A 1 35  ? 118.431 110.367 118.284 1.00 52.78  ? 35  SER L O   1 
ATOM 222  C CB  . SER A 1 35  ? 115.917 112.458 118.306 1.00 52.78  ? 35  SER L CB  1 
ATOM 223  O OG  . SER A 1 35  ? 116.961 113.036 119.066 1.00 52.78  ? 35  SER L OG  1 
ATOM 224  N N   . SER A 1 36  ? 117.486 110.621 116.249 1.00 53.10  ? 36  SER L N   1 
ATOM 225  C CA  . SER A 1 36  ? 118.738 110.359 115.546 1.00 53.10  ? 36  SER L CA  1 
ATOM 226  C C   . SER A 1 36  ? 119.781 111.414 115.887 1.00 53.10  ? 36  SER L C   1 
ATOM 227  O O   . SER A 1 36  ? 120.907 111.087 116.280 1.00 53.10  ? 36  SER L O   1 
ATOM 228  C CB  . SER A 1 36  ? 118.493 110.306 114.039 1.00 53.10  ? 36  SER L CB  1 
ATOM 229  O OG  . SER A 1 36  ? 119.671 109.929 113.348 1.00 53.10  ? 36  SER L OG  1 
ATOM 230  N N   . ASN A 1 37  ? 119.426 112.687 115.745 1.00 55.60  ? 37  ASN L N   1 
ATOM 231  C CA  . ASN A 1 37  ? 120.249 113.746 116.305 1.00 55.60  ? 37  ASN L CA  1 
ATOM 232  C C   . ASN A 1 37  ? 120.087 113.785 117.823 1.00 55.60  ? 37  ASN L C   1 
ATOM 233  O O   . ASN A 1 37  ? 119.071 113.350 118.373 1.00 55.60  ? 37  ASN L O   1 
ATOM 234  C CB  . ASN A 1 37  ? 119.902 115.096 115.669 1.00 55.60  ? 37  ASN L CB  1 
ATOM 235  C CG  . ASN A 1 37  ? 118.445 115.482 115.846 1.00 55.60  ? 37  ASN L CG  1 
ATOM 236  O OD1 . ASN A 1 37  ? 117.675 114.787 116.506 1.00 55.60  ? 37  ASN L OD1 1 
ATOM 237  N ND2 . ASN A 1 37  ? 118.061 116.605 115.253 1.00 55.60  ? 37  ASN L ND2 1 
ATOM 238  N N   . GLN A 1 38  ? 121.111 114.294 118.505 1.00 61.81  ? 38  GLN L N   1 
ATOM 239  C CA  . GLN A 1 38  ? 121.194 114.194 119.962 1.00 61.81  ? 38  GLN L CA  1 
ATOM 240  C C   . GLN A 1 38  ? 120.225 115.184 120.602 1.00 61.81  ? 38  GLN L C   1 
ATOM 241  O O   . GLN A 1 38  ? 120.583 116.298 120.993 1.00 61.81  ? 38  GLN L O   1 
ATOM 242  C CB  . GLN A 1 38  ? 122.624 114.432 120.434 1.00 61.81  ? 38  GLN L CB  1 
ATOM 243  C CG  . GLN A 1 38  ? 123.673 113.575 119.735 1.00 61.81  ? 38  GLN L CG  1 
ATOM 244  C CD  . GLN A 1 38  ? 123.151 112.206 119.337 1.00 61.81  ? 38  GLN L CD  1 
ATOM 245  O OE1 . GLN A 1 38  ? 122.800 111.389 120.189 1.00 61.81  ? 38  GLN L OE1 1 
ATOM 246  N NE2 . GLN A 1 38  ? 123.097 111.950 118.035 1.00 61.81  ? 38  GLN L NE2 1 
ATOM 247  N N   . LYS A 1 39  ? 118.968 114.757 120.723 1.00 55.09  ? 39  LYS L N   1 
ATOM 248  C CA  . LYS A 1 39  ? 117.914 115.562 121.326 1.00 55.09  ? 39  LYS L CA  1 
ATOM 249  C C   . LYS A 1 39  ? 117.187 114.736 122.377 1.00 55.09  ? 39  LYS L C   1 
ATOM 250  O O   . LYS A 1 39  ? 116.786 113.600 122.107 1.00 55.09  ? 39  LYS L O   1 
ATOM 251  C CB  . LYS A 1 39  ? 116.925 116.060 120.268 1.00 55.09  ? 39  LYS L CB  1 
ATOM 252  C CG  . LYS A 1 39  ? 116.927 117.565 120.070 1.00 55.09  ? 39  LYS L CG  1 
ATOM 253  C CD  . LYS A 1 39  ? 118.303 118.072 119.681 1.00 55.09  ? 39  LYS L CD  1 
ATOM 254  C CE  . LYS A 1 39  ? 118.334 119.588 119.607 1.00 55.09  ? 39  LYS L CE  1 
ATOM 255  N NZ  . LYS A 1 39  ? 119.715 120.105 119.408 1.00 55.09  ? 39  LYS L NZ  1 
ATOM 256  N N   . ASN A 1 40  ? 117.019 115.306 123.567 1.00 58.46  ? 40  ASN L N   1 
ATOM 257  C CA  . ASN A 1 40  ? 116.316 114.632 124.647 1.00 58.46  ? 40  ASN L CA  1 
ATOM 258  C C   . ASN A 1 40  ? 114.811 114.883 124.547 1.00 58.46  ? 40  ASN L C   1 
ATOM 259  O O   . ASN A 1 40  ? 114.351 115.810 123.877 1.00 58.46  ? 40  ASN L O   1 
ATOM 260  C CB  . ASN A 1 40  ? 116.846 115.099 126.000 1.00 58.46  ? 40  ASN L CB  1 
ATOM 261  C CG  . ASN A 1 40  ? 118.290 114.707 126.225 1.00 58.46  ? 40  ASN L CG  1 
ATOM 262  O OD1 . ASN A 1 40  ? 119.179 115.557 126.252 1.00 58.46  ? 40  ASN L OD1 1 
ATOM 263  N ND2 . ASN A 1 40  ? 118.532 113.413 126.387 1.00 58.46  ? 40  ASN L ND2 1 
ATOM 264  N N   . TYR A 1 41  ? 114.041 114.051 125.246 1.00 55.43  ? 41  TYR L N   1 
ATOM 265  C CA  . TYR A 1 41  ? 112.579 114.086 125.224 1.00 55.43  ? 41  TYR L CA  1 
ATOM 266  C C   . TYR A 1 41  ? 112.005 114.172 126.633 1.00 55.43  ? 41  TYR L C   1 
ATOM 267  O O   . TYR A 1 41  ? 111.159 113.369 127.030 1.00 55.43  ? 41  TYR L O   1 
ATOM 268  C CB  . TYR A 1 41  ? 111.974 112.871 124.520 1.00 55.43  ? 41  TYR L CB  1 
ATOM 269  C CG  . TYR A 1 41  ? 112.194 112.785 123.026 1.00 55.43  ? 41  TYR L CG  1 
ATOM 270  C CD1 . TYR A 1 41  ? 112.630 113.879 122.299 1.00 55.43  ? 41  TYR L CD1 1 
ATOM 271  C CD2 . TYR A 1 41  ? 111.920 111.614 122.337 1.00 55.43  ? 41  TYR L CD2 1 
ATOM 272  C CE1 . TYR A 1 41  ? 112.815 113.802 120.933 1.00 55.43  ? 41  TYR L CE1 1 
ATOM 273  C CE2 . TYR A 1 41  ? 112.098 111.528 120.973 1.00 55.43  ? 41  TYR L CE2 1 
ATOM 274  C CZ  . TYR A 1 41  ? 112.545 112.625 120.276 1.00 55.43  ? 41  TYR L CZ  1 
ATOM 275  O OH  . TYR A 1 41  ? 112.726 112.546 118.916 1.00 55.43  ? 41  TYR L OH  1 
ATOM 276  N N   . LEU A 1 42  ? 112.451 115.147 127.418 1.00 56.12  ? 42  LEU L N   1 
ATOM 277  C CA  . LEU A 1 42  ? 111.824 115.424 128.701 1.00 56.12  ? 42  LEU L CA  1 
ATOM 278  C C   . LEU A 1 42  ? 111.102 116.763 128.683 1.00 56.12  ? 42  LEU L C   1 
ATOM 279  O O   . LEU A 1 42  ? 111.331 117.614 127.820 1.00 56.12  ? 42  LEU L O   1 
ATOM 280  C CB  . LEU A 1 42  ? 112.836 115.414 129.847 1.00 56.12  ? 42  LEU L CB  1 
ATOM 281  C CG  . LEU A 1 42  ? 113.305 114.042 130.314 1.00 56.12  ? 42  LEU L CG  1 
ATOM 282  C CD1 . LEU A 1 42  ? 114.148 114.208 131.549 1.00 56.12  ? 42  LEU L CD1 1 
ATOM 283  C CD2 . LEU A 1 42  ? 112.117 113.144 130.599 1.00 56.12  ? 42  LEU L CD2 1 
ATOM 284  N N   . ALA A 1 43  ? 110.217 116.932 129.661 1.00 57.11  ? 43  ALA L N   1 
ATOM 285  C CA  . ALA A 1 43  ? 109.471 118.165 129.844 1.00 57.11  ? 43  ALA L CA  1 
ATOM 286  C C   . ALA A 1 43  ? 109.111 118.297 131.314 1.00 57.11  ? 43  ALA L C   1 
ATOM 287  O O   . ALA A 1 43  ? 108.807 117.301 131.974 1.00 57.11  ? 43  ALA L O   1 
ATOM 288  C CB  . ALA A 1 43  ? 108.206 118.196 128.980 1.00 57.11  ? 43  ALA L CB  1 
ATOM 289  N N   . TRP A 1 44  ? 109.147 119.525 131.819 1.00 62.31  ? 44  TRP L N   1 
ATOM 290  C CA  . TRP A 1 44  ? 108.877 119.809 133.221 1.00 62.31  ? 44  TRP L CA  1 
ATOM 291  C C   . TRP A 1 44  ? 107.561 120.562 133.345 1.00 62.31  ? 44  TRP L C   1 
ATOM 292  O O   . TRP A 1 44  ? 107.353 121.571 132.665 1.00 62.31  ? 44  TRP L O   1 
ATOM 293  C CB  . TRP A 1 44  ? 110.012 120.625 133.841 1.00 62.31  ? 44  TRP L CB  1 
ATOM 294  C CG  . TRP A 1 44  ? 111.267 119.843 134.061 1.00 62.31  ? 44  TRP L CG  1 
ATOM 295  C CD1 . TRP A 1 44  ? 112.310 119.709 133.194 1.00 62.31  ? 44  TRP L CD1 1 
ATOM 296  C CD2 . TRP A 1 44  ? 111.615 119.088 135.227 1.00 62.31  ? 44  TRP L CD2 1 
ATOM 297  N NE1 . TRP A 1 44  ? 113.285 118.917 133.746 1.00 62.31  ? 44  TRP L NE1 1 
ATOM 298  C CE2 . TRP A 1 44  ? 112.882 118.522 134.994 1.00 62.31  ? 44  TRP L CE2 1 
ATOM 299  C CE3 . TRP A 1 44  ? 110.976 118.835 136.443 1.00 62.31  ? 44  TRP L CE3 1 
ATOM 300  C CZ2 . TRP A 1 44  ? 113.523 117.720 135.932 1.00 62.31  ? 44  TRP L CZ2 1 
ATOM 301  C CZ3 . TRP A 1 44  ? 111.615 118.038 137.373 1.00 62.31  ? 44  TRP L CZ3 1 
ATOM 302  C CH2 . TRP A 1 44  ? 112.875 117.490 137.113 1.00 62.31  ? 44  TRP L CH2 1 
ATOM 303  N N   . TYR A 1 45  ? 106.682 120.073 134.214 1.00 61.66  ? 45  TYR L N   1 
ATOM 304  C CA  . TYR A 1 45  ? 105.401 120.707 134.479 1.00 61.66  ? 45  TYR L CA  1 
ATOM 305  C C   . TYR A 1 45  ? 105.323 121.122 135.940 1.00 61.66  ? 45  TYR L C   1 
ATOM 306  O O   . TYR A 1 45  ? 105.861 120.449 136.823 1.00 61.66  ? 45  TYR L O   1 
ATOM 307  C CB  . TYR A 1 45  ? 104.229 119.770 134.163 1.00 61.66  ? 45  TYR L CB  1 
ATOM 308  C CG  . TYR A 1 45  ? 104.174 119.279 132.737 1.00 61.66  ? 45  TYR L CG  1 
ATOM 309  C CD1 . TYR A 1 45  ? 104.883 118.156 132.344 1.00 61.66  ? 45  TYR L CD1 1 
ATOM 310  C CD2 . TYR A 1 45  ? 103.399 119.929 131.788 1.00 61.66  ? 45  TYR L CD2 1 
ATOM 311  C CE1 . TYR A 1 45  ? 104.832 117.699 131.046 1.00 61.66  ? 45  TYR L CE1 1 
ATOM 312  C CE2 . TYR A 1 45  ? 103.342 119.479 130.486 1.00 61.66  ? 45  TYR L CE2 1 
ATOM 313  C CZ  . TYR A 1 45  ? 104.060 118.363 130.122 1.00 61.66  ? 45  TYR L CZ  1 
ATOM 314  O OH  . TYR A 1 45  ? 104.008 117.908 128.826 1.00 61.66  ? 45  TYR L OH  1 
ATOM 315  N N   . GLN A 1 46  ? 104.646 122.239 136.188 1.00 69.80  ? 46  GLN L N   1 
ATOM 316  C CA  . GLN A 1 46  ? 104.321 122.676 137.537 1.00 69.80  ? 46  GLN L CA  1 
ATOM 317  C C   . GLN A 1 46  ? 102.812 122.838 137.647 1.00 69.80  ? 46  GLN L C   1 
ATOM 318  O O   . GLN A 1 46  ? 102.160 123.323 136.717 1.00 69.80  ? 46  GLN L O   1 
ATOM 319  C CB  . GLN A 1 46  ? 105.046 123.983 137.900 1.00 69.80  ? 46  GLN L CB  1 
ATOM 320  C CG  . GLN A 1 46  ? 104.384 125.262 137.417 1.00 69.80  ? 46  GLN L CG  1 
ATOM 321  C CD  . GLN A 1 46  ? 104.865 126.485 138.172 1.00 69.80  ? 46  GLN L CD  1 
ATOM 322  O OE1 . GLN A 1 46  ? 105.720 126.389 139.051 1.00 69.80  ? 46  GLN L OE1 1 
ATOM 323  N NE2 . GLN A 1 46  ? 104.314 127.645 137.834 1.00 69.80  ? 46  GLN L NE2 1 
ATOM 324  N N   . GLN A 1 47  ? 102.255 122.399 138.773 1.00 79.26  ? 47  GLN L N   1 
ATOM 325  C CA  . GLN A 1 47  ? 100.809 122.384 138.974 1.00 79.26  ? 47  GLN L CA  1 
ATOM 326  C C   . GLN A 1 47  ? 100.481 123.053 140.298 1.00 79.26  ? 47  GLN L C   1 
ATOM 327  O O   . GLN A 1 47  ? 100.821 122.527 141.361 1.00 79.26  ? 47  GLN L O   1 
ATOM 328  C CB  . GLN A 1 47  ? 100.259 120.959 138.952 1.00 79.26  ? 47  GLN L CB  1 
ATOM 329  C CG  . GLN A 1 47  ? 98.741  120.903 138.912 1.00 79.26  ? 47  GLN L CG  1 
ATOM 330  C CD  . GLN A 1 47  ? 98.174  119.751 139.711 1.00 79.26  ? 47  GLN L CD  1 
ATOM 331  O OE1 . GLN A 1 47  ? 98.912  118.904 140.212 1.00 79.26  ? 47  GLN L OE1 1 
ATOM 332  N NE2 . GLN A 1 47  ? 96.853  119.717 139.840 1.00 79.26  ? 47  GLN L NE2 1 
ATOM 333  N N   . ASN A 1 48  ? 99.806  124.196 140.234 1.00 86.10  ? 48  ASN L N   1 
ATOM 334  C CA  . ASN A 1 48  ? 99.274  124.800 141.440 1.00 86.10  ? 48  ASN L CA  1 
ATOM 335  C C   . ASN A 1 48  ? 98.188  123.898 142.026 1.00 86.10  ? 48  ASN L C   1 
ATOM 336  O O   . ASN A 1 48  ? 97.546  123.136 141.299 1.00 86.10  ? 48  ASN L O   1 
ATOM 337  C CB  . ASN A 1 48  ? 98.706  126.185 141.141 1.00 86.10  ? 48  ASN L CB  1 
ATOM 338  C CG  . ASN A 1 48  ? 99.789  127.213 140.872 1.00 86.10  ? 48  ASN L CG  1 
ATOM 339  O OD1 . ASN A 1 48  ? 99.931  127.703 139.752 1.00 86.10  ? 48  ASN L OD1 1 
ATOM 340  N ND2 . ASN A 1 48  ? 100.558 127.546 141.902 1.00 86.10  ? 48  ASN L ND2 1 
ATOM 341  N N   . PRO A 1 49  ? 97.970  123.956 143.343 1.00 90.86  ? 49  PRO L N   1 
ATOM 342  C CA  . PRO A 1 49  ? 96.997  123.041 143.963 1.00 90.86  ? 49  PRO L CA  1 
ATOM 343  C C   . PRO A 1 49  ? 95.571  123.227 143.473 1.00 90.86  ? 49  PRO L C   1 
ATOM 344  O O   . PRO A 1 49  ? 94.742  122.333 143.682 1.00 90.86  ? 49  PRO L O   1 
ATOM 345  C CB  . PRO A 1 49  ? 97.119  123.360 145.461 1.00 90.86  ? 49  PRO L CB  1 
ATOM 346  C CG  . PRO A 1 49  ? 97.736  124.720 145.519 1.00 90.86  ? 49  PRO L CG  1 
ATOM 347  C CD  . PRO A 1 49  ? 98.652  124.795 144.341 1.00 90.86  ? 49  PRO L CD  1 
ATOM 348  N N   . GLY A 1 50  ? 95.255  124.349 142.831 1.00 91.32  ? 50  GLY L N   1 
ATOM 349  C CA  . GLY A 1 50  ? 93.888  124.618 142.431 1.00 91.32  ? 50  GLY L CA  1 
ATOM 350  C C   . GLY A 1 50  ? 93.496  124.141 141.046 1.00 91.32  ? 50  GLY L C   1 
ATOM 351  O O   . GLY A 1 50  ? 92.517  123.404 140.900 1.00 91.32  ? 50  GLY L O   1 
ATOM 352  N N   . GLN A 1 51  ? 94.245  124.540 140.023 1.00 87.62  ? 51  GLN L N   1 
ATOM 353  C CA  . GLN A 1 51  ? 93.837  124.331 138.639 1.00 87.62  ? 51  GLN L CA  1 
ATOM 354  C C   . GLN A 1 51  ? 94.844  123.440 137.907 1.00 87.62  ? 51  GLN L C   1 
ATOM 355  O O   . GLN A 1 51  ? 95.770  122.884 138.503 1.00 87.62  ? 51  GLN L O   1 
ATOM 356  C CB  . GLN A 1 51  ? 93.650  125.678 137.934 1.00 87.62  ? 51  GLN L CB  1 
ATOM 357  C CG  . GLN A 1 51  ? 94.937  126.375 137.510 1.00 87.62  ? 51  GLN L CG  1 
ATOM 358  C CD  . GLN A 1 51  ? 95.744  126.891 138.684 1.00 87.62  ? 51  GLN L CD  1 
ATOM 359  O OE1 . GLN A 1 51  ? 95.207  127.127 139.766 1.00 87.62  ? 51  GLN L OE1 1 
ATOM 360  N NE2 . GLN A 1 51  ? 97.040  127.078 138.471 1.00 87.62  ? 51  GLN L NE2 1 
ATOM 361  N N   . SER A 1 52  ? 94.640  123.307 136.597 1.00 80.90  ? 52  SER L N   1 
ATOM 362  C CA  . SER A 1 52  ? 95.450  122.421 135.778 1.00 80.90  ? 52  SER L CA  1 
ATOM 363  C C   . SER A 1 52  ? 96.891  122.926 135.686 1.00 80.90  ? 52  SER L C   1 
ATOM 364  O O   . SER A 1 52  ? 97.145  124.127 135.811 1.00 80.90  ? 52  SER L O   1 
ATOM 365  C CB  . SER A 1 52  ? 94.851  122.306 134.380 1.00 80.90  ? 52  SER L CB  1 
ATOM 366  O OG  . SER A 1 52  ? 94.603  123.587 133.830 1.00 80.90  ? 52  SER L OG  1 
ATOM 367  N N   . PRO A 1 53  ? 97.849  122.030 135.467 1.00 72.59  ? 53  PRO L N   1 
ATOM 368  C CA  . PRO A 1 53  ? 99.255  122.438 135.407 1.00 72.59  ? 53  PRO L CA  1 
ATOM 369  C C   . PRO A 1 53  ? 99.589  123.162 134.109 1.00 72.59  ? 53  PRO L C   1 
ATOM 370  O O   . PRO A 1 53  ? 98.788  123.248 133.178 1.00 72.59  ? 53  PRO L O   1 
ATOM 371  C CB  . PRO A 1 53  ? 100.013 121.111 135.497 1.00 72.59  ? 53  PRO L CB  1 
ATOM 372  C CG  . PRO A 1 53  ? 99.071  120.113 134.970 1.00 72.59  ? 53  PRO L CG  1 
ATOM 373  C CD  . PRO A 1 53  ? 97.700  120.569 135.371 1.00 72.59  ? 53  PRO L CD  1 
ATOM 374  N N   . LYS A 1 54  ? 100.812 123.685 134.071 1.00 67.48  ? 54  LYS L N   1 
ATOM 375  C CA  . LYS A 1 54  ? 101.337 124.399 132.920 1.00 67.48  ? 54  LYS L CA  1 
ATOM 376  C C   . LYS A 1 54  ? 102.635 123.744 132.472 1.00 67.48  ? 54  LYS L C   1 
ATOM 377  O O   . LYS A 1 54  ? 103.234 122.945 133.197 1.00 67.48  ? 54  LYS L O   1 
ATOM 378  C CB  . LYS A 1 54  ? 101.584 125.880 133.239 1.00 67.48  ? 54  LYS L CB  1 
ATOM 379  C CG  . LYS A 1 54  ? 100.326 126.729 133.283 1.00 67.48  ? 54  LYS L CG  1 
ATOM 380  C CD  . LYS A 1 54  ? 99.712  126.734 134.673 1.00 67.48  ? 54  LYS L CD  1 
ATOM 381  C CE  . LYS A 1 54  ? 100.573 127.512 135.654 1.00 67.48  ? 54  LYS L CE  1 
ATOM 382  N NZ  . LYS A 1 54  ? 99.912  127.653 136.981 1.00 67.48  ? 54  LYS L NZ  1 
ATOM 383  N N   . LEU A 1 55  ? 103.065 124.090 131.264 1.00 58.91  ? 55  LEU L N   1 
ATOM 384  C CA  . LEU A 1 55  ? 104.318 123.600 130.709 1.00 58.91  ? 55  LEU L CA  1 
ATOM 385  C C   . LEU A 1 55  ? 105.399 124.657 130.892 1.00 58.91  ? 55  LEU L C   1 
ATOM 386  O O   . LEU A 1 55  ? 105.166 125.844 130.650 1.00 58.91  ? 55  LEU L O   1 
ATOM 387  C CB  . LEU A 1 55  ? 104.157 123.249 129.227 1.00 58.91  ? 55  LEU L CB  1 
ATOM 388  C CG  . LEU A 1 55  ? 105.299 122.540 128.495 1.00 58.91  ? 55  LEU L CG  1 
ATOM 389  C CD1 . LEU A 1 55  ? 104.737 121.721 127.355 1.00 58.91  ? 55  LEU L CD1 1 
ATOM 390  C CD2 . LEU A 1 55  ? 106.323 123.522 127.961 1.00 58.91  ? 55  LEU L CD2 1 
ATOM 391  N N   . LEU A 1 56  ? 106.582 124.220 131.323 1.00 59.70  ? 56  LEU L N   1 
ATOM 392  C CA  . LEU A 1 56  ? 107.684 125.129 131.612 1.00 59.70  ? 56  LEU L CA  1 
ATOM 393  C C   . LEU A 1 56  ? 108.850 124.957 130.647 1.00 59.70  ? 56  LEU L C   1 
ATOM 394  O O   . LEU A 1 56  ? 109.257 125.919 129.991 1.00 59.70  ? 56  LEU L O   1 
ATOM 395  C CB  . LEU A 1 56  ? 108.158 124.929 133.057 1.00 59.70  ? 56  LEU L CB  1 
ATOM 396  C CG  . LEU A 1 56  ? 107.214 125.411 134.157 1.00 59.70  ? 56  LEU L CG  1 
ATOM 397  C CD1 . LEU A 1 56  ? 107.854 125.230 135.523 1.00 59.70  ? 56  LEU L CD1 1 
ATOM 398  C CD2 . LEU A 1 56  ? 106.830 126.862 133.932 1.00 59.70  ? 56  LEU L CD2 1 
ATOM 399  N N   . ILE A 1 57  ? 109.403 123.751 130.541 1.00 56.40  ? 57  ILE L N   1 
ATOM 400  C CA  . ILE A 1 57  ? 110.587 123.490 129.730 1.00 56.40  ? 57  ILE L CA  1 
ATOM 401  C C   . ILE A 1 57  ? 110.350 122.224 128.921 1.00 56.40  ? 57  ILE L C   1 
ATOM 402  O O   . ILE A 1 57  ? 109.864 121.224 129.459 1.00 56.40  ? 57  ILE L O   1 
ATOM 403  C CB  . ILE A 1 57  ? 111.850 123.343 130.601 1.00 56.40  ? 57  ILE L CB  1 
ATOM 404  C CG1 . ILE A 1 57  ? 112.149 124.645 131.344 1.00 56.40  ? 57  ILE L CG1 1 
ATOM 405  C CG2 . ILE A 1 57  ? 113.044 122.931 129.758 1.00 56.40  ? 57  ILE L CG2 1 
ATOM 406  C CD1 . ILE A 1 57  ? 113.211 124.505 132.408 1.00 56.40  ? 57  ILE L CD1 1 
ATOM 407  N N   . TYR A 1 58  ? 110.689 122.266 127.634 1.00 52.67  ? 58  TYR L N   1 
ATOM 408  C CA  . TYR A 1 58  ? 110.671 121.083 126.788 1.00 52.67  ? 58  TYR L CA  1 
ATOM 409  C C   . TYR A 1 58  ? 112.028 120.934 126.114 1.00 52.67  ? 58  TYR L C   1 
ATOM 410  O O   . TYR A 1 58  ? 112.831 121.869 126.079 1.00 52.67  ? 58  TYR L O   1 
ATOM 411  C CB  . TYR A 1 58  ? 109.543 121.136 125.745 1.00 52.67  ? 58  TYR L CB  1 
ATOM 412  C CG  . TYR A 1 58  ? 109.481 122.406 124.929 1.00 52.67  ? 58  TYR L CG  1 
ATOM 413  C CD1 . TYR A 1 58  ? 108.791 123.516 125.389 1.00 52.67  ? 58  TYR L CD1 1 
ATOM 414  C CD2 . TYR A 1 58  ? 110.093 122.485 123.690 1.00 52.67  ? 58  TYR L CD2 1 
ATOM 415  C CE1 . TYR A 1 58  ? 108.726 124.675 124.642 1.00 52.67  ? 58  TYR L CE1 1 
ATOM 416  C CE2 . TYR A 1 58  ? 110.035 123.638 122.936 1.00 52.67  ? 58  TYR L CE2 1 
ATOM 417  C CZ  . TYR A 1 58  ? 109.349 124.729 123.416 1.00 52.67  ? 58  TYR L CZ  1 
ATOM 418  O OH  . TYR A 1 58  ? 109.288 125.881 122.667 1.00 52.67  ? 58  TYR L OH  1 
ATOM 419  N N   . TRP A 1 59  ? 112.279 119.733 125.593 1.00 50.20  ? 59  TRP L N   1 
ATOM 420  C CA  . TRP A 1 59  ? 113.584 119.283 125.110 1.00 50.20  ? 59  TRP L CA  1 
ATOM 421  C C   . TRP A 1 59  ? 114.646 119.292 126.203 1.00 50.20  ? 59  TRP L C   1 
ATOM 422  O O   . TRP A 1 59  ? 115.838 119.161 125.901 1.00 50.20  ? 59  TRP L O   1 
ATOM 423  C CB  . TRP A 1 59  ? 114.084 120.105 123.912 1.00 50.20  ? 59  TRP L CB  1 
ATOM 424  C CG  . TRP A 1 59  ? 113.128 120.214 122.761 1.00 50.20  ? 59  TRP L CG  1 
ATOM 425  C CD1 . TRP A 1 59  ? 112.693 121.363 122.175 1.00 50.20  ? 59  TRP L CD1 1 
ATOM 426  C CD2 . TRP A 1 59  ? 112.501 119.140 122.049 1.00 50.20  ? 59  TRP L CD2 1 
ATOM 427  N NE1 . TRP A 1 59  ? 111.830 121.077 121.149 1.00 50.20  ? 59  TRP L NE1 1 
ATOM 428  C CE2 . TRP A 1 59  ? 111.695 119.718 121.050 1.00 50.20  ? 59  TRP L CE2 1 
ATOM 429  C CE3 . TRP A 1 59  ? 112.539 117.748 122.160 1.00 50.20  ? 59  TRP L CE3 1 
ATOM 430  C CZ2 . TRP A 1 59  ? 110.935 118.955 120.170 1.00 50.20  ? 59  TRP L CZ2 1 
ATOM 431  C CZ3 . TRP A 1 59  ? 111.782 116.994 121.285 1.00 50.20  ? 59  TRP L CZ3 1 
ATOM 432  C CH2 . TRP A 1 59  ? 110.993 117.597 120.304 1.00 50.20  ? 59  TRP L CH2 1 
ATOM 433  N N   . ALA A 1 60  ? 114.242 119.468 127.461 1.00 56.83  ? 60  ALA L N   1 
ATOM 434  C CA  . ALA A 1 60  ? 115.073 119.469 128.663 1.00 56.83  ? 60  ALA L CA  1 
ATOM 435  C C   . ALA A 1 60  ? 116.004 120.670 128.757 1.00 56.83  ? 60  ALA L C   1 
ATOM 436  O O   . ALA A 1 60  ? 116.682 120.823 129.779 1.00 56.83  ? 60  ALA L O   1 
ATOM 437  C CB  . ALA A 1 60  ? 115.909 118.188 128.800 1.00 56.83  ? 60  ALA L CB  1 
ATOM 438  N N   . SER A 1 61  ? 116.068 121.529 127.738 1.00 60.55  ? 61  SER L N   1 
ATOM 439  C CA  . SER A 1 61  ? 116.907 122.716 127.814 1.00 60.55  ? 61  SER L CA  1 
ATOM 440  C C   . SER A 1 61  ? 116.295 123.956 127.178 1.00 60.55  ? 61  SER L C   1 
ATOM 441  O O   . SER A 1 61  ? 116.961 124.996 127.147 1.00 60.55  ? 61  SER L O   1 
ATOM 442  C CB  . SER A 1 61  ? 118.274 122.445 127.166 1.00 60.55  ? 61  SER L CB  1 
ATOM 443  O OG  . SER A 1 61  ? 119.073 123.616 127.159 1.00 60.55  ? 61  SER L OG  1 
ATOM 444  N N   . THR A 1 62  ? 115.065 123.893 126.676 1.00 61.33  ? 62  THR L N   1 
ATOM 445  C CA  . THR A 1 62  ? 114.444 125.008 125.972 1.00 61.33  ? 62  THR L CA  1 
ATOM 446  C C   . THR A 1 62  ? 113.285 125.544 126.801 1.00 61.33  ? 62  THR L C   1 
ATOM 447  O O   . THR A 1 62  ? 112.369 124.793 127.152 1.00 61.33  ? 62  THR L O   1 
ATOM 448  C CB  . THR A 1 62  ? 113.959 124.579 124.587 1.00 61.33  ? 62  THR L CB  1 
ATOM 449  O OG1 . THR A 1 62  ? 115.087 124.356 123.732 1.00 61.33  ? 62  THR L OG1 1 
ATOM 450  C CG2 . THR A 1 62  ? 113.073 125.652 123.977 1.00 61.33  ? 62  THR L CG2 1 
ATOM 451  N N   . ARG A 1 63  ? 113.328 126.836 127.108 1.00 76.65  ? 63  ARG L N   1 
ATOM 452  C CA  . ARG A 1 63  ? 112.263 127.475 127.864 1.00 76.65  ? 63  ARG L CA  1 
ATOM 453  C C   . ARG A 1 63  ? 111.063 127.756 126.969 1.00 76.65  ? 63  ARG L C   1 
ATOM 454  O O   . ARG A 1 63  ? 111.204 128.112 125.796 1.00 76.65  ? 63  ARG L O   1 
ATOM 455  C CB  . ARG A 1 63  ? 112.757 128.776 128.494 1.00 76.65  ? 63  ARG L CB  1 
ATOM 456  C CG  . ARG A 1 63  ? 113.780 128.578 129.598 1.00 76.65  ? 63  ARG L CG  1 
ATOM 457  C CD  . ARG A 1 63  ? 114.077 129.882 130.313 1.00 76.65  ? 63  ARG L CD  1 
ATOM 458  N NE  . ARG A 1 63  ? 114.693 130.852 129.417 1.00 76.65  ? 63  ARG L NE  1 
ATOM 459  C CZ  . ARG A 1 63  ? 115.998 130.950 129.203 1.00 76.65  ? 63  ARG L CZ  1 
ATOM 460  N NH1 . ARG A 1 63  ? 116.859 130.146 129.805 1.00 76.65  ? 63  ARG L NH1 1 
ATOM 461  N NH2 . ARG A 1 63  ? 116.450 131.876 128.361 1.00 76.65  ? 63  ARG L NH2 1 
ATOM 462  N N   . GLU A 1 64  ? 109.874 127.589 127.536 1.00 79.41  ? 64  GLU L N   1 
ATOM 463  C CA  . GLU A 1 64  ? 108.636 127.845 126.819 1.00 79.41  ? 64  GLU L CA  1 
ATOM 464  C C   . GLU A 1 64  ? 108.315 129.334 126.836 1.00 79.41  ? 64  GLU L C   1 
ATOM 465  O O   . GLU A 1 64  ? 108.675 130.056 127.770 1.00 79.41  ? 64  GLU L O   1 
ATOM 466  C CB  . GLU A 1 64  ? 107.485 127.048 127.434 1.00 79.41  ? 64  GLU L CB  1 
ATOM 467  C CG  . GLU A 1 64  ? 106.297 126.858 126.508 1.00 79.41  ? 64  GLU L CG  1 
ATOM 468  C CD  . GLU A 1 64  ? 105.186 127.847 126.783 1.00 79.41  ? 64  GLU L CD  1 
ATOM 469  O OE1 . GLU A 1 64  ? 105.043 128.270 127.949 1.00 79.41  ? 64  GLU L OE1 1 
ATOM 470  O OE2 . GLU A 1 64  ? 104.454 128.200 125.835 1.00 79.41  ? 64  GLU L OE2 1 
ATOM 471  N N   . SER A 1 65  ? 107.641 129.790 125.782 1.00 86.49  ? 65  SER L N   1 
ATOM 472  C CA  . SER A 1 65  ? 107.304 131.202 125.658 1.00 86.49  ? 65  SER L CA  1 
ATOM 473  C C   . SER A 1 65  ? 106.372 131.634 126.783 1.00 86.49  ? 65  SER L C   1 
ATOM 474  O O   . SER A 1 65  ? 105.402 130.941 127.104 1.00 86.49  ? 65  SER L O   1 
ATOM 475  C CB  . SER A 1 65  ? 106.656 131.470 124.300 1.00 86.49  ? 65  SER L CB  1 
ATOM 476  O OG  . SER A 1 65  ? 106.203 132.808 124.207 1.00 86.49  ? 65  SER L OG  1 
ATOM 477  N N   . GLY A 1 66  ? 106.665 132.787 127.377 1.00 92.13  ? 66  GLY L N   1 
ATOM 478  C CA  . GLY A 1 66  ? 105.877 133.281 128.486 1.00 92.13  ? 66  GLY L CA  1 
ATOM 479  C C   . GLY A 1 66  ? 106.320 132.797 129.846 1.00 92.13  ? 66  GLY L C   1 
ATOM 480  O O   . GLY A 1 66  ? 105.499 132.738 130.769 1.00 92.13  ? 66  GLY L O   1 
ATOM 481  N N   . VAL A 1 67  ? 107.592 132.446 130.003 1.00 91.19  ? 67  VAL L N   1 
ATOM 482  C CA  . VAL A 1 67  ? 108.118 131.944 131.270 1.00 91.19  ? 67  VAL L CA  1 
ATOM 483  C C   . VAL A 1 67  ? 109.262 132.848 131.715 1.00 91.19  ? 67  VAL L C   1 
ATOM 484  O O   . VAL A 1 67  ? 110.119 133.207 130.894 1.00 91.19  ? 67  VAL L O   1 
ATOM 485  C CB  . VAL A 1 67  ? 108.573 130.482 131.139 1.00 91.19  ? 67  VAL L CB  1 
ATOM 486  C CG1 . VAL A 1 67  ? 109.217 129.997 132.427 1.00 91.19  ? 67  VAL L CG1 1 
ATOM 487  C CG2 . VAL A 1 67  ? 107.396 129.594 130.768 1.00 91.19  ? 67  VAL L CG2 1 
ATOM 488  N N   . PRO A 1 68  ? 109.314 133.247 132.987 1.00 96.45  ? 68  PRO L N   1 
ATOM 489  C CA  . PRO A 1 68  ? 110.419 134.096 133.448 1.00 96.45  ? 68  PRO L CA  1 
ATOM 490  C C   . PRO A 1 68  ? 111.759 133.387 133.326 1.00 96.45  ? 68  PRO L C   1 
ATOM 491  O O   . PRO A 1 68  ? 111.850 132.159 133.394 1.00 96.45  ? 68  PRO L O   1 
ATOM 492  C CB  . PRO A 1 68  ? 110.066 134.381 134.913 1.00 96.45  ? 68  PRO L CB  1 
ATOM 493  C CG  . PRO A 1 68  ? 109.065 133.335 135.289 1.00 96.45  ? 68  PRO L CG  1 
ATOM 494  C CD  . PRO A 1 68  ? 108.309 133.025 134.039 1.00 96.45  ? 68  PRO L CD  1 
ATOM 495  N N   . ASP A 1 69  ? 112.812 134.186 133.141 1.00 96.75  ? 69  ASP L N   1 
ATOM 496  C CA  . ASP A 1 69  ? 114.147 133.658 132.891 1.00 96.75  ? 69  ASP L CA  1 
ATOM 497  C C   . ASP A 1 69  ? 114.764 132.994 134.116 1.00 96.75  ? 69  ASP L C   1 
ATOM 498  O O   . ASP A 1 69  ? 115.814 132.356 133.988 1.00 96.75  ? 69  ASP L O   1 
ATOM 499  C CB  . ASP A 1 69  ? 115.059 134.783 132.395 1.00 96.75  ? 69  ASP L CB  1 
ATOM 500  C CG  . ASP A 1 69  ? 116.276 134.269 131.648 1.00 96.75  ? 69  ASP L CG  1 
ATOM 501  O OD1 . ASP A 1 69  ? 116.384 133.042 131.444 1.00 96.75  ? 69  ASP L OD1 1 
ATOM 502  O OD2 . ASP A 1 69  ? 117.130 135.096 131.265 1.00 96.75  ? 69  ASP L OD2 1 
ATOM 503  N N   . ARG A 1 70  ? 114.147 133.123 135.292 1.00 103.85 ? 70  ARG L N   1 
ATOM 504  C CA  . ARG A 1 70  ? 114.714 132.533 136.500 1.00 103.85 ? 70  ARG L CA  1 
ATOM 505  C C   . ARG A 1 70  ? 114.788 131.012 136.428 1.00 103.85 ? 70  ARG L C   1 
ATOM 506  O O   . ARG A 1 70  ? 115.569 130.406 137.171 1.00 103.85 ? 70  ARG L O   1 
ATOM 507  C CB  . ARG A 1 70  ? 113.902 132.963 137.724 1.00 103.85 ? 70  ARG L CB  1 
ATOM 508  C CG  . ARG A 1 70  ? 112.525 132.331 137.809 1.00 103.85 ? 70  ARG L CG  1 
ATOM 509  C CD  . ARG A 1 70  ? 111.619 133.094 138.760 1.00 103.85 ? 70  ARG L CD  1 
ATOM 510  N NE  . ARG A 1 70  ? 111.256 134.405 138.235 1.00 103.85 ? 70  ARG L NE  1 
ATOM 511  C CZ  . ARG A 1 70  ? 110.144 135.056 138.549 1.00 103.85 ? 70  ARG L CZ  1 
ATOM 512  N NH1 . ARG A 1 70  ? 109.249 134.537 139.373 1.00 103.85 ? 70  ARG L NH1 1 
ATOM 513  N NH2 . ARG A 1 70  ? 109.923 136.255 138.019 1.00 103.85 ? 70  ARG L NH2 1 
ATOM 514  N N   . PHE A 1 71  ? 114.001 130.382 135.559 1.00 94.83  ? 71  PHE L N   1 
ATOM 515  C CA  . PHE A 1 71  ? 114.030 128.935 135.391 1.00 94.83  ? 71  PHE L CA  1 
ATOM 516  C C   . PHE A 1 71  ? 115.112 128.550 134.390 1.00 94.83  ? 71  PHE L C   1 
ATOM 517  O O   . PHE A 1 71  ? 115.314 129.243 133.388 1.00 94.83  ? 71  PHE L O   1 
ATOM 518  C CB  . PHE A 1 71  ? 112.670 128.419 134.919 1.00 94.83  ? 71  PHE L CB  1 
ATOM 519  C CG  . PHE A 1 71  ? 111.556 128.670 135.891 1.00 94.83  ? 71  PHE L CG  1 
ATOM 520  C CD1 . PHE A 1 71  ? 111.327 127.798 136.941 1.00 94.83  ? 71  PHE L CD1 1 
ATOM 521  C CD2 . PHE A 1 71  ? 110.737 129.776 135.754 1.00 94.83  ? 71  PHE L CD2 1 
ATOM 522  C CE1 . PHE A 1 71  ? 110.300 128.025 137.836 1.00 94.83  ? 71  PHE L CE1 1 
ATOM 523  C CE2 . PHE A 1 71  ? 109.709 130.009 136.646 1.00 94.83  ? 71  PHE L CE2 1 
ATOM 524  C CZ  . PHE A 1 71  ? 109.491 129.132 137.688 1.00 94.83  ? 71  PHE L CZ  1 
ATOM 525  N N   . THR A 1 72  ? 115.803 127.446 134.664 1.00 89.39  ? 72  THR L N   1 
ATOM 526  C CA  . THR A 1 72  ? 116.864 126.955 133.796 1.00 89.39  ? 72  THR L CA  1 
ATOM 527  C C   . THR A 1 72  ? 116.938 125.440 133.904 1.00 89.39  ? 72  THR L C   1 
ATOM 528  O O   . THR A 1 72  ? 116.878 124.886 135.004 1.00 89.39  ? 72  THR L O   1 
ATOM 529  C CB  . THR A 1 72  ? 118.221 127.576 134.162 1.00 89.39  ? 72  THR L CB  1 
ATOM 530  O OG1 . THR A 1 72  ? 118.136 129.003 134.073 1.00 89.39  ? 72  THR L OG1 1 
ATOM 531  C CG2 . THR A 1 72  ? 119.311 127.083 133.222 1.00 89.39  ? 72  THR L CG2 1 
ATOM 532  N N   . GLY A 1 73  ? 117.071 124.776 132.766 1.00 78.88  ? 73  GLY L N   1 
ATOM 533  C CA  . GLY A 1 73  ? 117.148 123.328 132.745 1.00 78.88  ? 73  GLY L CA  1 
ATOM 534  C C   . GLY A 1 73  ? 118.381 122.858 132.006 1.00 78.88  ? 73  GLY L C   1 
ATOM 535  O O   . GLY A 1 73  ? 118.778 123.426 130.987 1.00 78.88  ? 73  GLY L O   1 
ATOM 536  N N   . SER A 1 74  ? 118.991 121.805 132.542 1.00 82.08  ? 74  SER L N   1 
ATOM 537  C CA  . SER A 1 74  ? 120.130 121.151 131.920 1.00 82.08  ? 74  SER L CA  1 
ATOM 538  C C   . SER A 1 74  ? 119.905 119.647 131.939 1.00 82.08  ? 74  SER L C   1 
ATOM 539  O O   . SER A 1 74  ? 119.267 119.112 132.850 1.00 82.08  ? 74  SER L O   1 
ATOM 540  C CB  . SER A 1 74  ? 121.444 121.498 132.631 1.00 82.08  ? 74  SER L CB  1 
ATOM 541  O OG  . SER A 1 74  ? 121.378 121.182 134.010 1.00 82.08  ? 74  SER L OG  1 
ATOM 542  N N   . GLY A 1 75  ? 120.431 118.970 130.931 1.00 81.55  ? 75  GLY L N   1 
ATOM 543  C CA  . GLY A 1 75  ? 120.164 117.556 130.755 1.00 81.55  ? 75  GLY L CA  1 
ATOM 544  C C   . GLY A 1 75  ? 121.401 116.799 130.328 1.00 81.55  ? 75  GLY L C   1 
ATOM 545  O O   . GLY A 1 75  ? 122.363 117.371 129.810 1.00 81.55  ? 75  GLY L O   1 
ATOM 546  N N   . SER A 1 76  ? 121.362 115.488 130.558 1.00 83.20  ? 76  SER L N   1 
ATOM 547  C CA  . SER A 1 76  ? 122.429 114.584 130.149 1.00 83.20  ? 76  SER L CA  1 
ATOM 548  C C   . SER A 1 76  ? 121.820 113.335 129.529 1.00 83.20  ? 76  SER L C   1 
ATOM 549  O O   . SER A 1 76  ? 120.633 113.324 129.190 1.00 83.20  ? 76  SER L O   1 
ATOM 550  C CB  . SER A 1 76  ? 123.325 114.219 131.334 1.00 83.20  ? 76  SER L CB  1 
ATOM 551  O OG  . SER A 1 76  ? 122.561 113.739 132.424 1.00 83.20  ? 76  SER L OG  1 
ATOM 552  N N   . GLY A 1 77  ? 122.625 112.285 129.357 1.00 80.93  ? 77  GLY L N   1 
ATOM 553  C CA  . GLY A 1 77  ? 122.110 111.069 128.748 1.00 80.93  ? 77  GLY L CA  1 
ATOM 554  C C   . GLY A 1 77  ? 121.006 110.422 129.563 1.00 80.93  ? 77  GLY L C   1 
ATOM 555  O O   . GLY A 1 77  ? 119.963 110.040 129.027 1.00 80.93  ? 77  GLY L O   1 
ATOM 556  N N   . THR A 1 78  ? 121.219 110.289 130.875 1.00 84.60  ? 78  THR L N   1 
ATOM 557  C CA  . THR A 1 78  ? 120.241 109.626 131.726 1.00 84.60  ? 78  THR L CA  1 
ATOM 558  C C   . THR A 1 78  ? 120.044 110.277 133.089 1.00 84.60  ? 78  THR L C   1 
ATOM 559  O O   . THR A 1 78  ? 119.299 109.727 133.906 1.00 84.60  ? 78  THR L O   1 
ATOM 560  C CB  . THR A 1 78  ? 120.626 108.153 131.932 1.00 84.60  ? 78  THR L CB  1 
ATOM 561  O OG1 . THR A 1 78  ? 119.573 107.474 132.626 1.00 84.60  ? 78  THR L OG1 1 
ATOM 562  C CG2 . THR A 1 78  ? 121.908 108.048 132.741 1.00 84.60  ? 78  THR L CG2 1 
ATOM 563  N N   . ASP A 1 79  ? 120.676 111.416 133.367 1.00 87.42  ? 79  ASP L N   1 
ATOM 564  C CA  . ASP A 1 79  ? 120.564 112.080 134.666 1.00 87.42  ? 79  ASP L CA  1 
ATOM 565  C C   . ASP A 1 79  ? 120.266 113.555 134.413 1.00 87.42  ? 79  ASP L C   1 
ATOM 566  O O   . ASP A 1 79  ? 121.156 114.319 134.027 1.00 87.42  ? 79  ASP L O   1 
ATOM 567  C CB  . ASP A 1 79  ? 121.838 111.899 135.487 1.00 87.42  ? 79  ASP L CB  1 
ATOM 568  C CG  . ASP A 1 79  ? 121.690 112.390 136.917 1.00 87.42  ? 79  ASP L CG  1 
ATOM 569  O OD1 . ASP A 1 79  ? 120.607 112.903 137.270 1.00 87.42  ? 79  ASP L OD1 1 
ATOM 570  O OD2 . ASP A 1 79  ? 122.661 112.261 137.691 1.00 87.42  ? 79  ASP L OD2 1 
ATOM 571  N N   . PHE A 1 80  ? 119.020 113.953 134.640 1.00 80.76  ? 80  PHE L N   1 
ATOM 572  C CA  . PHE A 1 80  ? 118.558 115.304 134.367 1.00 80.76  ? 80  PHE L CA  1 
ATOM 573  C C   . PHE A 1 80  ? 118.309 116.060 135.667 1.00 80.76  ? 80  PHE L C   1 
ATOM 574  O O   . PHE A 1 80  ? 118.102 115.468 136.729 1.00 80.76  ? 80  PHE L O   1 
ATOM 575  C CB  . PHE A 1 80  ? 117.281 115.277 133.524 1.00 80.76  ? 80  PHE L CB  1 
ATOM 576  C CG  . PHE A 1 80  ? 117.411 114.495 132.247 1.00 80.76  ? 80  PHE L CG  1 
ATOM 577  C CD1 . PHE A 1 80  ? 117.305 113.113 132.246 1.00 80.76  ? 80  PHE L CD1 1 
ATOM 578  C CD2 . PHE A 1 80  ? 117.617 115.144 131.042 1.00 80.76  ? 80  PHE L CD2 1 
ATOM 579  C CE1 . PHE A 1 80  ? 117.416 112.396 131.073 1.00 80.76  ? 80  PHE L CE1 1 
ATOM 580  C CE2 . PHE A 1 80  ? 117.729 114.431 129.866 1.00 80.76  ? 80  PHE L CE2 1 
ATOM 581  C CZ  . PHE A 1 80  ? 117.627 113.056 129.881 1.00 80.76  ? 80  PHE L CZ  1 
ATOM 582  N N   . THR A 1 81  ? 118.327 117.387 135.567 1.00 85.98  ? 81  THR L N   1 
ATOM 583  C CA  . THR A 1 81  ? 118.135 118.248 136.724 1.00 85.98  ? 81  THR L CA  1 
ATOM 584  C C   . THR A 1 81  ? 117.441 119.534 136.296 1.00 85.98  ? 81  THR L C   1 
ATOM 585  O O   . THR A 1 81  ? 117.444 119.907 135.121 1.00 85.98  ? 81  THR L O   1 
ATOM 586  C CB  . THR A 1 81  ? 119.464 118.575 137.417 1.00 85.98  ? 81  THR L CB  1 
ATOM 587  O OG1 . THR A 1 81  ? 119.208 119.279 138.639 1.00 85.98  ? 81  THR L OG1 1 
ATOM 588  C CG2 . THR A 1 81  ? 120.338 119.433 136.520 1.00 85.98  ? 81  THR L CG2 1 
ATOM 589  N N   . LEU A 1 82  ? 116.837 120.206 137.275 1.00 89.16  ? 82  LEU L N   1 
ATOM 590  C CA  . LEU A 1 82  ? 116.152 121.476 137.065 1.00 89.16  ? 82  LEU L CA  1 
ATOM 591  C C   . LEU A 1 82  ? 116.573 122.436 138.165 1.00 89.16  ? 82  LEU L C   1 
ATOM 592  O O   . LEU A 1 82  ? 116.335 122.169 139.347 1.00 89.16  ? 82  LEU L O   1 
ATOM 593  C CB  . LEU A 1 82  ? 114.632 121.294 137.066 1.00 89.16  ? 82  LEU L CB  1 
ATOM 594  C CG  . LEU A 1 82  ? 113.796 122.568 137.210 1.00 89.16  ? 82  LEU L CG  1 
ATOM 595  C CD1 . LEU A 1 82  ? 114.061 123.523 136.057 1.00 89.16  ? 82  LEU L CD1 1 
ATOM 596  C CD2 . LEU A 1 82  ? 112.316 122.237 137.305 1.00 89.16  ? 82  LEU L CD2 1 
ATOM 597  N N   . THR A 1 83  ? 117.191 123.549 137.780 1.00 102.54 ? 83  THR L N   1 
ATOM 598  C CA  . THR A 1 83  ? 117.682 124.544 138.723 1.00 102.54 ? 83  THR L CA  1 
ATOM 599  C C   . THR A 1 83  ? 116.990 125.876 138.470 1.00 102.54 ? 83  THR L C   1 
ATOM 600  O O   . THR A 1 83  ? 116.833 126.294 137.318 1.00 102.54 ? 83  THR L O   1 
ATOM 601  C CB  . THR A 1 83  ? 119.207 124.694 138.630 1.00 102.54 ? 83  THR L CB  1 
ATOM 602  O OG1 . THR A 1 83  ? 119.655 125.676 139.572 1.00 102.54 ? 83  THR L OG1 1 
ATOM 603  C CG2 . THR A 1 83  ? 119.644 125.090 137.223 1.00 102.54 ? 83  THR L CG2 1 
ATOM 604  N N   . ILE A 1 84  ? 116.560 126.528 139.544 1.00 112.41 ? 84  ILE L N   1 
ATOM 605  C CA  . ILE A 1 84  ? 115.888 127.819 139.469 1.00 112.41 ? 84  ILE L CA  1 
ATOM 606  C C   . ILE A 1 84  ? 116.765 128.862 140.147 1.00 112.41 ? 84  ILE L C   1 
ATOM 607  O O   . ILE A 1 84  ? 117.282 128.631 141.247 1.00 112.41 ? 84  ILE L O   1 
ATOM 608  C CB  . ILE A 1 84  ? 114.489 127.757 140.108 1.00 112.41 ? 84  ILE L CB  1 
ATOM 609  C CG1 . ILE A 1 84  ? 113.850 129.146 140.144 1.00 112.41 ? 84  ILE L CG1 1 
ATOM 610  C CG2 . ILE A 1 84  ? 114.551 127.141 141.496 1.00 112.41 ? 84  ILE L CG2 1 
ATOM 611  C CD1 . ILE A 1 84  ? 112.402 129.136 140.573 1.00 112.41 ? 84  ILE L CD1 1 
ATOM 612  N N   . SER A 1 85  ? 116.943 130.007 139.487 1.00 119.60 ? 85  SER L N   1 
ATOM 613  C CA  . SER A 1 85  ? 117.796 131.079 139.999 1.00 119.60 ? 85  SER L CA  1 
ATOM 614  C C   . SER A 1 85  ? 117.074 131.758 141.160 1.00 119.60 ? 85  SER L C   1 
ATOM 615  O O   . SER A 1 85  ? 116.459 132.818 141.022 1.00 119.60 ? 85  SER L O   1 
ATOM 616  C CB  . SER A 1 85  ? 118.138 132.071 138.894 1.00 119.60 ? 85  SER L CB  1 
ATOM 617  O OG  . SER A 1 85  ? 118.855 133.179 139.409 1.00 119.60 ? 85  SER L OG  1 
ATOM 618  N N   . SER A 1 86  ? 117.154 131.111 142.327 1.00 125.79 ? 86  SER L N   1 
ATOM 619  C CA  . SER A 1 86  ? 116.468 131.516 143.552 1.00 125.79 ? 86  SER L CA  1 
ATOM 620  C C   . SER A 1 86  ? 114.953 131.425 143.399 1.00 125.79 ? 86  SER L C   1 
ATOM 621  O O   . SER A 1 86  ? 114.425 131.481 142.284 1.00 125.79 ? 86  SER L O   1 
ATOM 622  C CB  . SER A 1 86  ? 116.884 132.929 143.974 1.00 125.79 ? 86  SER L CB  1 
ATOM 623  O OG  . SER A 1 86  ? 118.163 132.922 144.584 1.00 125.79 ? 86  SER L OG  1 
ATOM 624  N N   . VAL A 1 87  ? 114.244 131.284 144.514 1.00 122.77 ? 87  VAL L N   1 
ATOM 625  C CA  . VAL A 1 87  ? 112.798 131.103 144.512 1.00 122.77 ? 87  VAL L CA  1 
ATOM 626  C C   . VAL A 1 87  ? 112.132 132.439 144.817 1.00 122.77 ? 87  VAL L C   1 
ATOM 627  O O   . VAL A 1 87  ? 112.545 133.157 145.735 1.00 122.77 ? 87  VAL L O   1 
ATOM 628  C CB  . VAL A 1 87  ? 112.371 130.010 145.509 1.00 122.77 ? 87  VAL L CB  1 
ATOM 629  C CG1 . VAL A 1 87  ? 112.783 130.366 146.927 1.00 122.77 ? 87  VAL L CG1 1 
ATOM 630  C CG2 . VAL A 1 87  ? 110.872 129.779 145.435 1.00 122.77 ? 87  VAL L CG2 1 
ATOM 631  N N   . LYS A 1 88  ? 111.126 132.788 144.021 1.00 118.40 ? 88  LYS L N   1 
ATOM 632  C CA  . LYS A 1 88  ? 110.383 134.026 144.178 1.00 118.40 ? 88  LYS L CA  1 
ATOM 633  C C   . LYS A 1 88  ? 109.151 133.790 145.048 1.00 118.40 ? 88  LYS L C   1 
ATOM 634  O O   . LYS A 1 88  ? 109.016 132.756 145.710 1.00 118.40 ? 88  LYS L O   1 
ATOM 635  C CB  . LYS A 1 88  ? 110.013 134.595 142.807 1.00 118.40 ? 88  LYS L CB  1 
ATOM 636  C CG  . LYS A 1 88  ? 111.205 135.042 141.976 1.00 118.40 ? 88  LYS L CG  1 
ATOM 637  C CD  . LYS A 1 88  ? 112.159 135.899 142.792 1.00 118.40 ? 88  LYS L CD  1 
ATOM 638  C CE  . LYS A 1 88  ? 113.587 135.767 142.291 1.00 118.40 ? 88  LYS L CE  1 
ATOM 639  N NZ  . LYS A 1 88  ? 114.293 134.621 142.923 1.00 118.40 ? 88  LYS L NZ  1 
ATOM 640  N N   . ALA A 1 89  ? 108.241 134.766 145.058 1.00 118.76 ? 89  ALA L N   1 
ATOM 641  C CA  . ALA A 1 89  ? 107.059 134.676 145.908 1.00 118.76 ? 89  ALA L CA  1 
ATOM 642  C C   . ALA A 1 89  ? 106.154 133.526 145.482 1.00 118.76 ? 89  ALA L C   1 
ATOM 643  O O   . ALA A 1 89  ? 105.735 132.711 146.312 1.00 118.76 ? 89  ALA L O   1 
ATOM 644  C CB  . ALA A 1 89  ? 106.296 136.000 145.885 1.00 118.76 ? 89  ALA L CB  1 
ATOM 645  N N   . GLU A 1 90  ? 105.844 133.439 144.191 1.00 115.60 ? 90  GLU L N   1 
ATOM 646  C CA  . GLU A 1 90  ? 104.953 132.406 143.665 1.00 115.60 ? 90  GLU L CA  1 
ATOM 647  C C   . GLU A 1 90  ? 105.768 131.453 142.795 1.00 115.60 ? 90  GLU L C   1 
ATOM 648  O O   . GLU A 1 90  ? 105.802 131.565 141.569 1.00 115.60 ? 90  GLU L O   1 
ATOM 649  C CB  . GLU A 1 90  ? 103.795 133.033 142.885 1.00 115.60 ? 90  GLU L CB  1 
ATOM 650  C CG  . GLU A 1 90  ? 102.754 133.714 143.757 1.00 115.60 ? 90  GLU L CG  1 
ATOM 651  C CD  . GLU A 1 90  ? 102.559 133.016 145.089 1.00 115.60 ? 90  GLU L CD  1 
ATOM 652  O OE1 . GLU A 1 90  ? 101.909 131.951 145.114 1.00 115.60 ? 90  GLU L OE1 1 
ATOM 653  O OE2 . GLU A 1 90  ? 103.050 133.537 146.113 1.00 115.60 ? 90  GLU L OE2 1 
ATOM 654  N N   . ASP A 1 91  ? 106.431 130.499 143.451 1.00 108.40 ? 91  ASP L N   1 
ATOM 655  C CA  . ASP A 1 91  ? 107.114 129.405 142.772 1.00 108.40 ? 91  ASP L CA  1 
ATOM 656  C C   . ASP A 1 91  ? 106.919 128.097 143.528 1.00 108.40 ? 91  ASP L C   1 
ATOM 657  O O   . ASP A 1 91  ? 107.790 127.220 143.500 1.00 108.40 ? 91  ASP L O   1 
ATOM 658  C CB  . ASP A 1 91  ? 108.604 129.703 142.599 1.00 108.40 ? 91  ASP L CB  1 
ATOM 659  C CG  . ASP A 1 91  ? 108.894 130.526 141.359 1.00 108.40 ? 91  ASP L CG  1 
ATOM 660  O OD1 . ASP A 1 91  ? 108.135 130.409 140.374 1.00 108.40 ? 91  ASP L OD1 1 
ATOM 661  O OD2 . ASP A 1 91  ? 109.882 131.291 141.368 1.00 108.40 ? 91  ASP L OD2 1 
ATOM 662  N N   . LEU A 1 92  ? 105.787 127.956 144.206 1.00 95.07  ? 92  LEU L N   1 
ATOM 663  C CA  . LEU A 1 92  ? 105.512 126.820 145.073 1.00 95.07  ? 92  LEU L CA  1 
ATOM 664  C C   . LEU A 1 92  ? 104.847 125.707 144.260 1.00 95.07  ? 92  LEU L C   1 
ATOM 665  O O   . LEU A 1 92  ? 104.920 125.695 143.028 1.00 95.07  ? 92  LEU L O   1 
ATOM 666  C CB  . LEU A 1 92  ? 104.657 127.267 146.265 1.00 95.07  ? 92  LEU L CB  1 
ATOM 667  C CG  . LEU A 1 92  ? 105.346 127.901 147.481 1.00 95.07  ? 92  LEU L CG  1 
ATOM 668  C CD1 . LEU A 1 92  ? 106.279 126.903 148.155 1.00 95.07  ? 92  LEU L CD1 1 
ATOM 669  C CD2 . LEU A 1 92  ? 106.087 129.186 147.127 1.00 95.07  ? 92  LEU L CD2 1 
ATOM 670  N N   . ALA A 1 93  ? 104.250 124.734 144.955 1.00 86.88  ? 93  ALA L N   1 
ATOM 671  C CA  . ALA A 1 93  ? 103.410 123.683 144.385 1.00 86.88  ? 93  ALA L CA  1 
ATOM 672  C C   . ALA A 1 93  ? 104.230 122.586 143.715 1.00 86.88  ? 93  ALA L C   1 
ATOM 673  O O   . ALA A 1 93  ? 105.457 122.682 143.619 1.00 86.88  ? 93  ALA L O   1 
ATOM 674  C CB  . ALA A 1 93  ? 102.392 124.269 143.403 1.00 86.88  ? 93  ALA L CB  1 
ATOM 675  N N   . ILE A 1 94  ? 103.548 121.541 143.251 1.00 78.43  ? 94  ILE L N   1 
ATOM 676  C CA  . ILE A 1 94  ? 104.197 120.306 142.823 1.00 78.43  ? 94  ILE L CA  1 
ATOM 677  C C   . ILE A 1 94  ? 104.805 120.490 141.440 1.00 78.43  ? 94  ILE L C   1 
ATOM 678  O O   . ILE A 1 94  ? 104.220 121.140 140.565 1.00 78.43  ? 94  ILE L O   1 
ATOM 679  C CB  . ILE A 1 94  ? 103.201 119.129 142.841 1.00 78.43  ? 94  ILE L CB  1 
ATOM 680  C CG1 . ILE A 1 94  ? 102.479 119.004 144.191 1.00 78.43  ? 94  ILE L CG1 1 
ATOM 681  C CG2 . ILE A 1 94  ? 103.904 117.822 142.514 1.00 78.43  ? 94  ILE L CG2 1 
ATOM 682  C CD1 . ILE A 1 94  ? 101.246 119.881 144.361 1.00 78.43  ? 94  ILE L CD1 1 
ATOM 683  N N   . TYR A 1 95  ? 105.985 119.908 141.239 1.00 76.12  ? 95  TYR L N   1 
ATOM 684  C CA  . TYR A 1 95  ? 106.672 119.908 139.954 1.00 76.12  ? 95  TYR L CA  1 
ATOM 685  C C   . TYR A 1 95  ? 106.754 118.482 139.428 1.00 76.12  ? 95  TYR L C   1 
ATOM 686  O O   . TYR A 1 95  ? 107.188 117.576 140.147 1.00 76.12  ? 95  TYR L O   1 
ATOM 687  C CB  . TYR A 1 95  ? 108.077 120.503 140.080 1.00 76.12  ? 95  TYR L CB  1 
ATOM 688  C CG  . TYR A 1 95  ? 108.107 122.010 140.182 1.00 76.12  ? 95  TYR L CG  1 
ATOM 689  C CD1 . TYR A 1 95  ? 107.471 122.670 141.224 1.00 76.12  ? 95  TYR L CD1 1 
ATOM 690  C CD2 . TYR A 1 95  ? 108.775 122.773 139.236 1.00 76.12  ? 95  TYR L CD2 1 
ATOM 691  C CE1 . TYR A 1 95  ? 107.498 124.046 141.319 1.00 76.12  ? 95  TYR L CE1 1 
ATOM 692  C CE2 . TYR A 1 95  ? 108.808 124.149 139.323 1.00 76.12  ? 95  TYR L CE2 1 
ATOM 693  C CZ  . TYR A 1 95  ? 108.167 124.780 140.366 1.00 76.12  ? 95  TYR L CZ  1 
ATOM 694  O OH  . TYR A 1 95  ? 108.198 126.152 140.455 1.00 76.12  ? 95  TYR L OH  1 
ATOM 695  N N   . TYR A 1 96  ? 106.345 118.287 138.179 1.00 70.70  ? 96  TYR L N   1 
ATOM 696  C CA  . TYR A 1 96  ? 106.326 116.974 137.552 1.00 70.70  ? 96  TYR L CA  1 
ATOM 697  C C   . TYR A 1 96  ? 107.327 116.908 136.405 1.00 70.70  ? 96  TYR L C   1 
ATOM 698  O O   . TYR A 1 96  ? 107.755 117.928 135.860 1.00 70.70  ? 96  TYR L O   1 
ATOM 699  C CB  . TYR A 1 96  ? 104.926 116.634 137.032 1.00 70.70  ? 96  TYR L CB  1 
ATOM 700  C CG  . TYR A 1 96  ? 103.913 116.359 138.116 1.00 70.70  ? 96  TYR L CG  1 
ATOM 701  C CD1 . TYR A 1 96  ? 104.189 115.465 139.139 1.00 70.70  ? 96  TYR L CD1 1 
ATOM 702  C CD2 . TYR A 1 96  ? 102.678 116.991 138.114 1.00 70.70  ? 96  TYR L CD2 1 
ATOM 703  C CE1 . TYR A 1 96  ? 103.266 115.209 140.131 1.00 70.70  ? 96  TYR L CE1 1 
ATOM 704  C CE2 . TYR A 1 96  ? 101.749 116.743 139.102 1.00 70.70  ? 96  TYR L CE2 1 
ATOM 705  C CZ  . TYR A 1 96  ? 102.048 115.851 140.108 1.00 70.70  ? 96  TYR L CZ  1 
ATOM 706  O OH  . TYR A 1 96  ? 101.124 115.600 141.096 1.00 70.70  ? 96  TYR L OH  1 
ATOM 707  N N   . CYS A 1 97  ? 107.692 115.680 136.045 1.00 65.20  ? 97  CYS L N   1 
ATOM 708  C CA  . CYS A 1 97  ? 108.559 115.412 134.908 1.00 65.20  ? 97  CYS L CA  1 
ATOM 709  C C   . CYS A 1 97  ? 107.930 114.322 134.052 1.00 65.20  ? 97  CYS L C   1 
ATOM 710  O O   . CYS A 1 97  ? 107.281 113.408 134.565 1.00 65.20  ? 97  CYS L O   1 
ATOM 711  C CB  . CYS A 1 97  ? 109.964 114.992 135.355 1.00 65.20  ? 97  CYS L CB  1 
ATOM 712  S SG  . CYS A 1 97  ? 110.022 113.446 136.285 1.00 65.20  ? 97  CYS L SG  1 
ATOM 713  N N   . GLN A 1 98  ? 108.124 114.429 132.739 1.00 57.45  ? 98  GLN L N   1 
ATOM 714  C CA  . GLN A 1 98  ? 107.470 113.526 131.804 1.00 57.45  ? 98  GLN L CA  1 
ATOM 715  C C   . GLN A 1 98  ? 108.373 113.275 130.607 1.00 57.45  ? 98  GLN L C   1 
ATOM 716  O O   . GLN A 1 98  ? 109.097 114.172 130.170 1.00 57.45  ? 98  GLN L O   1 
ATOM 717  C CB  . GLN A 1 98  ? 106.133 114.101 131.325 1.00 57.45  ? 98  GLN L CB  1 
ATOM 718  C CG  . GLN A 1 98  ? 105.343 113.171 130.420 1.00 57.45  ? 98  GLN L CG  1 
ATOM 719  C CD  . GLN A 1 98  ? 104.365 113.911 129.531 1.00 57.45  ? 98  GLN L CD  1 
ATOM 720  O OE1 . GLN A 1 98  ? 104.462 115.125 129.357 1.00 57.45  ? 98  GLN L OE1 1 
ATOM 721  N NE2 . GLN A 1 98  ? 103.412 113.181 128.964 1.00 57.45  ? 98  GLN L NE2 1 
ATOM 722  N N   . GLN A 1 99  ? 108.321 112.054 130.084 1.00 56.55  ? 99  GLN L N   1 
ATOM 723  C CA  . GLN A 1 99  ? 108.906 111.714 128.796 1.00 56.55  ? 99  GLN L CA  1 
ATOM 724  C C   . GLN A 1 99  ? 107.779 111.420 127.815 1.00 56.55  ? 99  GLN L C   1 
ATOM 725  O O   . GLN A 1 99  ? 106.783 110.785 128.174 1.00 56.55  ? 99  GLN L O   1 
ATOM 726  C CB  . GLN A 1 99  ? 109.859 110.520 128.915 1.00 56.55  ? 99  GLN L CB  1 
ATOM 727  C CG  . GLN A 1 99  ? 109.193 109.183 129.189 1.00 56.55  ? 99  GLN L CG  1 
ATOM 728  C CD  . GLN A 1 99  ? 108.993 108.369 127.928 1.00 56.55  ? 99  GLN L CD  1 
ATOM 729  O OE1 . GLN A 1 99  ? 109.715 108.538 126.947 1.00 56.55  ? 99  GLN L OE1 1 
ATOM 730  N NE2 . GLN A 1 99  ? 108.012 107.475 127.950 1.00 56.55  ? 99  GLN L NE2 1 
ATOM 731  N N   . TYR A 1 100 ? 107.920 111.904 126.584 1.00 52.93  ? 100 TYR L N   1 
ATOM 732  C CA  . TYR A 1 100 ? 106.819 111.915 125.625 1.00 52.93  ? 100 TYR L CA  1 
ATOM 733  C C   . TYR A 1 100 ? 107.221 111.250 124.315 1.00 52.93  ? 100 TYR L C   1 
ATOM 734  O O   . TYR A 1 100 ? 107.004 111.781 123.225 1.00 52.93  ? 100 TYR L O   1 
ATOM 735  C CB  . TYR A 1 100 ? 106.327 113.339 125.383 1.00 52.93  ? 100 TYR L CB  1 
ATOM 736  C CG  . TYR A 1 100 ? 107.429 114.364 125.259 1.00 52.93  ? 100 TYR L CG  1 
ATOM 737  C CD1 . TYR A 1 100 ? 108.006 114.648 124.031 1.00 52.93  ? 100 TYR L CD1 1 
ATOM 738  C CD2 . TYR A 1 100 ? 107.884 115.057 126.370 1.00 52.93  ? 100 TYR L CD2 1 
ATOM 739  C CE1 . TYR A 1 100 ? 109.009 115.587 123.915 1.00 52.93  ? 100 TYR L CE1 1 
ATOM 740  C CE2 . TYR A 1 100 ? 108.887 115.996 126.263 1.00 52.93  ? 100 TYR L CE2 1 
ATOM 741  C CZ  . TYR A 1 100 ? 109.445 116.257 125.034 1.00 52.93  ? 100 TYR L CZ  1 
ATOM 742  O OH  . TYR A 1 100 ? 110.444 117.194 124.924 1.00 52.93  ? 100 TYR L OH  1 
ATOM 743  N N   . PHE A 1 101 ? 107.811 110.063 124.405 1.00 58.77  ? 101 PHE L N   1 
ATOM 744  C CA  . PHE A 1 101 ? 108.061 109.224 123.243 1.00 58.77  ? 101 PHE L CA  1 
ATOM 745  C C   . PHE A 1 101 ? 107.464 107.847 123.487 1.00 58.77  ? 101 PHE L C   1 
ATOM 746  O O   . PHE A 1 101 ? 107.497 107.341 124.614 1.00 58.77  ? 101 PHE L O   1 
ATOM 747  C CB  . PHE A 1 101 ? 109.555 109.103 122.943 1.00 58.77  ? 101 PHE L CB  1 
ATOM 748  C CG  . PHE A 1 101 ? 109.853 108.571 121.572 1.00 58.77  ? 101 PHE L CG  1 
ATOM 749  C CD1 . PHE A 1 101 ? 109.475 109.279 120.444 1.00 58.77  ? 101 PHE L CD1 1 
ATOM 750  C CD2 . PHE A 1 101 ? 110.504 107.362 121.408 1.00 58.77  ? 101 PHE L CD2 1 
ATOM 751  C CE1 . PHE A 1 101 ? 109.746 108.794 119.182 1.00 58.77  ? 101 PHE L CE1 1 
ATOM 752  C CE2 . PHE A 1 101 ? 110.777 106.872 120.147 1.00 58.77  ? 101 PHE L CE2 1 
ATOM 753  C CZ  . PHE A 1 101 ? 110.397 107.589 119.033 1.00 58.77  ? 101 PHE L CZ  1 
ATOM 754  N N   . ARG A 1 102 ? 106.915 107.248 122.427 1.00 66.03  ? 102 ARG L N   1 
ATOM 755  C CA  . ARG A 1 102 ? 106.233 105.961 122.522 1.00 66.03  ? 102 ARG L CA  1 
ATOM 756  C C   . ARG A 1 102 ? 105.095 106.023 123.531 1.00 66.03  ? 102 ARG L C   1 
ATOM 757  O O   . ARG A 1 102 ? 103.985 106.454 123.201 1.00 66.03  ? 102 ARG L O   1 
ATOM 758  C CB  . ARG A 1 102 ? 107.215 104.845 122.894 1.00 66.03  ? 102 ARG L CB  1 
ATOM 759  C CG  . ARG A 1 102 ? 108.299 104.562 121.860 1.00 66.03  ? 102 ARG L CG  1 
ATOM 760  C CD  . ARG A 1 102 ? 107.721 104.005 120.563 1.00 66.03  ? 102 ARG L CD  1 
ATOM 761  N NE  . ARG A 1 102 ? 107.288 105.040 119.632 1.00 66.03  ? 102 ARG L NE  1 
ATOM 762  C CZ  . ARG A 1 102 ? 106.537 104.815 118.563 1.00 66.03  ? 102 ARG L CZ  1 
ATOM 763  N NH1 . ARG A 1 102 ? 106.116 103.599 118.258 1.00 66.03  ? 102 ARG L NH1 1 
ATOM 764  N NH2 . ARG A 1 102 ? 106.200 105.835 117.780 1.00 66.03  ? 102 ARG L NH2 1 
ATOM 765  N N   . TYR A 1 103 ? 105.360 105.599 124.762 1.00 64.86  ? 103 TYR L N   1 
ATOM 766  C CA  . TYR A 1 103 ? 104.349 105.598 125.811 1.00 64.86  ? 103 TYR L CA  1 
ATOM 767  C C   . TYR A 1 103 ? 104.706 106.631 126.869 1.00 64.86  ? 103 TYR L C   1 
ATOM 768  O O   . TYR A 1 103 ? 105.647 106.410 127.648 1.00 64.86  ? 103 TYR L O   1 
ATOM 769  C CB  . TYR A 1 103 ? 104.228 104.210 126.440 1.00 64.86  ? 103 TYR L CB  1 
ATOM 770  C CG  . TYR A 1 103 ? 103.472 103.221 125.583 1.00 64.86  ? 103 TYR L CG  1 
ATOM 771  C CD1 . TYR A 1 103 ? 104.074 102.049 125.145 1.00 64.86  ? 103 TYR L CD1 1 
ATOM 772  C CD2 . TYR A 1 103 ? 102.157 103.460 125.210 1.00 64.86  ? 103 TYR L CD2 1 
ATOM 773  C CE1 . TYR A 1 103 ? 103.387 101.143 124.361 1.00 64.86  ? 103 TYR L CE1 1 
ATOM 774  C CE2 . TYR A 1 103 ? 101.463 102.560 124.427 1.00 64.86  ? 103 TYR L CE2 1 
ATOM 775  C CZ  . TYR A 1 103 ? 102.082 101.404 124.005 1.00 64.86  ? 103 TYR L CZ  1 
ATOM 776  O OH  . TYR A 1 103 ? 101.392 100.506 123.225 1.00 64.86  ? 103 TYR L OH  1 
ATOM 777  N N   . PRO A 1 104 ? 104.007 107.762 126.935 1.00 57.50  ? 104 PRO L N   1 
ATOM 778  C CA  . PRO A 1 104 ? 104.311 108.756 127.969 1.00 57.50  ? 104 PRO L CA  1 
ATOM 779  C C   . PRO A 1 104 ? 104.053 108.207 129.361 1.00 57.50  ? 104 PRO L C   1 
ATOM 780  O O   . PRO A 1 104 ? 103.174 107.369 129.573 1.00 57.50  ? 104 PRO L O   1 
ATOM 781  C CB  . PRO A 1 104 ? 103.360 109.913 127.642 1.00 57.50  ? 104 PRO L CB  1 
ATOM 782  C CG  . PRO A 1 104 ? 102.972 109.703 126.215 1.00 57.50  ? 104 PRO L CG  1 
ATOM 783  C CD  . PRO A 1 104 ? 102.953 108.223 126.019 1.00 57.50  ? 104 PRO L CD  1 
ATOM 784  N N   . ALA A 1 105 ? 104.838 108.694 130.319 1.00 55.17  ? 105 ALA L N   1 
ATOM 785  C CA  . ALA A 1 105 ? 104.735 108.216 131.695 1.00 55.17  ? 105 ALA L CA  1 
ATOM 786  C C   . ALA A 1 105 ? 105.239 109.300 132.630 1.00 55.17  ? 105 ALA L C   1 
ATOM 787  O O   . ALA A 1 105 ? 106.415 109.671 132.569 1.00 55.17  ? 105 ALA L O   1 
ATOM 788  C CB  . ALA A 1 105 ? 105.529 106.926 131.885 1.00 55.17  ? 105 ALA L CB  1 
ATOM 789  N N   . PHE A 1 106 ? 104.359 109.799 133.491 1.00 58.44  ? 106 PHE L N   1 
ATOM 790  C CA  . PHE A 1 106 ? 104.729 110.787 134.495 1.00 58.44  ? 106 PHE L CA  1 
ATOM 791  C C   . PHE A 1 106 ? 105.386 110.079 135.677 1.00 58.44  ? 106 PHE L C   1 
ATOM 792  O O   . PHE A 1 106 ? 105.785 108.914 135.594 1.00 58.44  ? 106 PHE L O   1 
ATOM 793  C CB  . PHE A 1 106 ? 103.505 111.589 134.929 1.00 58.44  ? 106 PHE L CB  1 
ATOM 794  C CG  . PHE A 1 106 ? 102.917 112.442 133.844 1.00 58.44  ? 106 PHE L CG  1 
ATOM 795  C CD1 . PHE A 1 106 ? 102.081 111.894 132.888 1.00 58.44  ? 106 PHE L CD1 1 
ATOM 796  C CD2 . PHE A 1 106 ? 103.193 113.796 133.787 1.00 58.44  ? 106 PHE L CD2 1 
ATOM 797  C CE1 . PHE A 1 106 ? 101.537 112.678 131.894 1.00 58.44  ? 106 PHE L CE1 1 
ATOM 798  C CE2 . PHE A 1 106 ? 102.651 114.585 132.795 1.00 58.44  ? 106 PHE L CE2 1 
ATOM 799  C CZ  . PHE A 1 106 ? 101.822 114.025 131.847 1.00 58.44  ? 106 PHE L CZ  1 
ATOM 800  N N   . GLY A 1 107 ? 105.511 110.780 136.799 1.00 68.62  ? 107 GLY L N   1 
ATOM 801  C CA  . GLY A 1 107 ? 106.017 110.159 138.006 1.00 68.62  ? 107 GLY L CA  1 
ATOM 802  C C   . GLY A 1 107 ? 106.725 111.110 138.946 1.00 68.62  ? 107 GLY L C   1 
ATOM 803  O O   . GLY A 1 107 ? 107.540 111.931 138.516 1.00 68.62  ? 107 GLY L O   1 
ATOM 804  N N   . GLY A 1 108 ? 106.421 111.005 140.231 1.00 76.59  ? 108 GLY L N   1 
ATOM 805  C CA  . GLY A 1 108 ? 107.074 111.792 141.255 1.00 76.59  ? 108 GLY L CA  1 
ATOM 806  C C   . GLY A 1 108 ? 106.159 112.862 141.823 1.00 76.59  ? 108 GLY L C   1 
ATOM 807  O O   . GLY A 1 108 ? 104.944 112.875 141.606 1.00 76.59  ? 108 GLY L O   1 
ATOM 808  N N   . GLY A 1 109 ? 106.773 113.771 142.563 1.00 78.95  ? 109 GLY L N   1 
ATOM 809  C CA  . GLY A 1 109 ? 106.066 114.868 143.201 1.00 78.95  ? 109 GLY L CA  1 
ATOM 810  C C   . GLY A 1 109 ? 106.988 116.050 143.384 1.00 78.95  ? 109 GLY L C   1 
ATOM 811  O O   . GLY A 1 109 ? 107.915 116.257 142.595 1.00 78.95  ? 109 GLY L O   1 
ATOM 812  N N   . THR A 1 110 ? 106.734 116.830 144.431 1.00 80.36  ? 110 THR L N   1 
ATOM 813  C CA  . THR A 1 110 ? 107.532 118.015 144.725 1.00 80.36  ? 110 THR L CA  1 
ATOM 814  C C   . THR A 1 110 ? 108.976 117.646 145.044 1.00 80.36  ? 110 THR L C   1 
ATOM 815  O O   . THR A 1 110 ? 109.832 117.629 144.161 1.00 80.36  ? 110 THR L O   1 
ATOM 816  C CB  . THR A 1 110 ? 106.946 118.812 145.907 1.00 80.36  ? 110 THR L CB  1 
ATOM 817  O OG1 . THR A 1 110 ? 105.519 118.863 145.794 1.00 80.36  ? 110 THR L OG1 1 
ATOM 818  C CG2 . THR A 1 110 ? 107.500 120.228 145.925 1.00 80.36  ? 110 THR L CG2 1 
ATOM 819  N N   . VAL B 2 5   ? 94.896  127.638 120.763 1.00 97.78  ? 5   VAL H N   1 
ATOM 820  C CA  . VAL B 2 5   ? 93.691  126.831 120.898 1.00 97.78  ? 5   VAL H CA  1 
ATOM 821  C C   . VAL B 2 5   ? 93.366  126.622 122.374 1.00 97.78  ? 5   VAL H C   1 
ATOM 822  O O   . VAL B 2 5   ? 94.262  126.463 123.202 1.00 97.78  ? 5   VAL H O   1 
ATOM 823  C CB  . VAL B 2 5   ? 93.839  125.481 120.158 1.00 97.78  ? 5   VAL H CB  1 
ATOM 824  C CG1 . VAL B 2 5   ? 94.949  124.640 120.774 1.00 97.78  ? 5   VAL H CG1 1 
ATOM 825  C CG2 . VAL B 2 5   ? 92.521  124.720 120.155 1.00 97.78  ? 5   VAL H CG2 1 
ATOM 826  N N   . GLN B 2 6   ? 92.076  126.646 122.702 1.00 103.13 ? 6   GLN H N   1 
ATOM 827  C CA  . GLN B 2 6   ? 91.620  126.420 124.065 1.00 103.13 ? 6   GLN H CA  1 
ATOM 828  C C   . GLN B 2 6   ? 90.474  125.421 124.045 1.00 103.13 ? 6   GLN H C   1 
ATOM 829  O O   . GLN B 2 6   ? 89.638  125.438 123.137 1.00 103.13 ? 6   GLN H O   1 
ATOM 830  C CB  . GLN B 2 6   ? 91.201  127.740 124.740 1.00 103.13 ? 6   GLN H CB  1 
ATOM 831  C CG  . GLN B 2 6   ? 89.887  128.354 124.261 1.00 103.13 ? 6   GLN H CG  1 
ATOM 832  C CD  . GLN B 2 6   ? 88.668  127.769 124.951 1.00 103.13 ? 6   GLN H CD  1 
ATOM 833  O OE1 . GLN B 2 6   ? 88.536  127.844 126.172 1.00 103.13 ? 6   GLN H OE1 1 
ATOM 834  N NE2 . GLN B 2 6   ? 87.770  127.182 124.168 1.00 103.13 ? 6   GLN H NE2 1 
ATOM 835  N N   . LEU B 2 7   ? 90.451  124.541 125.043 1.00 97.80  ? 7   LEU H N   1 
ATOM 836  C CA  . LEU B 2 7   ? 89.419  123.523 125.158 1.00 97.80  ? 7   LEU H CA  1 
ATOM 837  C C   . LEU B 2 7   ? 88.973  123.425 126.608 1.00 97.80  ? 7   LEU H C   1 
ATOM 838  O O   . LEU B 2 7   ? 89.775  123.615 127.525 1.00 97.80  ? 7   LEU H O   1 
ATOM 839  C CB  . LEU B 2 7   ? 89.922  122.163 124.648 1.00 97.80  ? 7   LEU H CB  1 
ATOM 840  C CG  . LEU B 2 7   ? 91.184  121.560 125.275 1.00 97.80  ? 7   LEU H CG  1 
ATOM 841  C CD1 . LEU B 2 7   ? 90.864  120.685 126.480 1.00 97.80  ? 7   LEU H CD1 1 
ATOM 842  C CD2 . LEU B 2 7   ? 91.971  120.778 124.236 1.00 97.80  ? 7   LEU H CD2 1 
ATOM 843  N N   . GLN B 2 8   ? 87.690  123.134 126.809 1.00 103.62 ? 8   GLN H N   1 
ATOM 844  C CA  . GLN B 2 8   ? 87.120  123.005 128.141 1.00 103.62 ? 8   GLN H CA  1 
ATOM 845  C C   . GLN B 2 8   ? 86.265  121.748 128.216 1.00 103.62 ? 8   GLN H C   1 
ATOM 846  O O   . GLN B 2 8   ? 85.651  121.342 127.224 1.00 103.62 ? 8   GLN H O   1 
ATOM 847  C CB  . GLN B 2 8   ? 86.287  124.243 128.522 1.00 103.62 ? 8   GLN H CB  1 
ATOM 848  C CG  . GLN B 2 8   ? 84.943  124.374 127.818 1.00 103.62 ? 8   GLN H CG  1 
ATOM 849  C CD  . GLN B 2 8   ? 85.077  124.622 126.330 1.00 103.62 ? 8   GLN H CD  1 
ATOM 850  O OE1 . GLN B 2 8   ? 85.813  125.511 125.901 1.00 103.62 ? 8   GLN H OE1 1 
ATOM 851  N NE2 . GLN B 2 8   ? 84.362  123.839 125.534 1.00 103.62 ? 8   GLN H NE2 1 
ATOM 852  N N   . GLN B 2 9   ? 86.238  121.133 129.394 1.00 101.81 ? 9   GLN H N   1 
ATOM 853  C CA  . GLN B 2 9   ? 85.477  119.915 129.618 1.00 101.81 ? 9   GLN H CA  1 
ATOM 854  C C   . GLN B 2 9   ? 84.039  120.260 130.003 1.00 101.81 ? 9   GLN H C   1 
ATOM 855  O O   . GLN B 2 9   ? 83.651  121.428 130.071 1.00 101.81 ? 9   GLN H O   1 
ATOM 856  C CB  . GLN B 2 9   ? 86.151  119.063 130.692 1.00 101.81 ? 9   GLN H CB  1 
ATOM 857  C CG  . GLN B 2 9   ? 86.050  117.569 130.453 1.00 101.81 ? 9   GLN H CG  1 
ATOM 858  C CD  . GLN B 2 9   ? 87.050  116.783 131.273 1.00 101.81 ? 9   GLN H CD  1 
ATOM 859  O OE1 . GLN B 2 9   ? 87.835  117.354 132.028 1.00 101.81 ? 9   GLN H OE1 1 
ATOM 860  N NE2 . GLN B 2 9   ? 87.029  115.464 131.126 1.00 101.81 ? 9   GLN H NE2 1 
ATOM 861  N N   . SER B 2 10  ? 83.238  119.227 130.257 1.00 103.64 ? 10  SER H N   1 
ATOM 862  C CA  . SER B 2 10  ? 81.796  119.392 130.441 1.00 103.64 ? 10  SER H CA  1 
ATOM 863  C C   . SER B 2 10  ? 81.335  118.818 131.780 1.00 103.64 ? 10  SER H C   1 
ATOM 864  O O   . SER B 2 10  ? 80.865  117.680 131.849 1.00 103.64 ? 10  SER H O   1 
ATOM 865  C CB  . SER B 2 10  ? 81.043  118.742 129.281 1.00 103.64 ? 10  SER H CB  1 
ATOM 866  O OG  . SER B 2 10  ? 80.975  117.336 129.444 1.00 103.64 ? 10  SER H OG  1 
ATOM 867  N N   . GLY B 2 11  ? 81.470  119.611 132.841 1.00 106.23 ? 11  GLY H N   1 
ATOM 868  C CA  . GLY B 2 11  ? 80.685  119.441 134.043 1.00 106.23 ? 11  GLY H CA  1 
ATOM 869  C C   . GLY B 2 11  ? 81.097  118.304 134.956 1.00 106.23 ? 11  GLY H C   1 
ATOM 870  O O   . GLY B 2 11  ? 81.409  117.194 134.515 1.00 106.23 ? 11  GLY H O   1 
ATOM 871  N N   . PRO B 2 12  ? 81.094  118.567 136.263 1.00 108.46 ? 12  PRO H N   1 
ATOM 872  C CA  . PRO B 2 12  ? 81.228  117.475 137.235 1.00 108.46 ? 12  PRO H CA  1 
ATOM 873  C C   . PRO B 2 12  ? 80.074  116.490 137.117 1.00 108.46 ? 12  PRO H C   1 
ATOM 874  O O   . PRO B 2 12  ? 78.959  116.846 136.730 1.00 108.46 ? 12  PRO H O   1 
ATOM 875  C CB  . PRO B 2 12  ? 81.201  118.192 138.589 1.00 108.46 ? 12  PRO H CB  1 
ATOM 876  C CG  . PRO B 2 12  ? 81.538  119.618 138.310 1.00 108.46 ? 12  PRO H CG  1 
ATOM 877  C CD  . PRO B 2 12  ? 81.471  119.872 136.831 1.00 108.46 ? 12  PRO H CD  1 
ATOM 878  N N   . GLU B 2 13  ? 80.355  115.234 137.460 1.00 115.77 ? 13  GLU H N   1 
ATOM 879  C CA  . GLU B 2 13  ? 79.350  114.181 137.429 1.00 115.77 ? 13  GLU H CA  1 
ATOM 880  C C   . GLU B 2 13  ? 79.417  113.374 138.717 1.00 115.77 ? 13  GLU H C   1 
ATOM 881  O O   . GLU B 2 13  ? 80.468  113.278 139.355 1.00 115.77 ? 13  GLU H O   1 
ATOM 882  C CB  . GLU B 2 13  ? 79.538  113.253 136.222 1.00 115.77 ? 13  GLU H CB  1 
ATOM 883  C CG  . GLU B 2 13  ? 78.771  113.681 134.983 1.00 115.77 ? 13  GLU H CG  1 
ATOM 884  C CD  . GLU B 2 13  ? 78.474  112.520 134.057 1.00 115.77 ? 13  GLU H CD  1 
ATOM 885  O OE1 . GLU B 2 13  ? 78.883  111.384 134.376 1.00 115.77 ? 13  GLU H OE1 1 
ATOM 886  O OE2 . GLU B 2 13  ? 77.832  112.742 133.009 1.00 115.77 ? 13  GLU H OE2 1 
ATOM 887  N N   . LEU B 2 14  ? 78.278  112.793 139.092 1.00 122.93 ? 14  LEU H N   1 
ATOM 888  C CA  . LEU B 2 14  ? 78.163  111.962 140.291 1.00 122.93 ? 14  LEU H CA  1 
ATOM 889  C C   . LEU B 2 14  ? 77.427  110.681 139.909 1.00 122.93 ? 14  LEU H C   1 
ATOM 890  O O   . LEU B 2 14  ? 76.268  110.725 139.487 1.00 122.93 ? 14  LEU H O   1 
ATOM 891  C CB  . LEU B 2 14  ? 77.442  112.704 141.412 1.00 122.93 ? 14  LEU H CB  1 
ATOM 892  C CG  . LEU B 2 14  ? 77.534  112.078 142.806 1.00 122.93 ? 14  LEU H CG  1 
ATOM 893  C CD1 . LEU B 2 14  ? 78.929  111.531 143.065 1.00 122.93 ? 14  LEU H CD1 1 
ATOM 894  C CD2 . LEU B 2 14  ? 77.144  113.086 143.874 1.00 122.93 ? 14  LEU H CD2 1 
ATOM 895  N N   . VAL B 2 15  ? 78.101  109.546 140.060 1.00 127.74 ? 15  VAL H N   1 
ATOM 896  C CA  . VAL B 2 15  ? 77.548  108.247 139.696 1.00 127.74 ? 15  VAL H CA  1 
ATOM 897  C C   . VAL B 2 15  ? 77.612  107.329 140.909 1.00 127.74 ? 15  VAL H C   1 
ATOM 898  O O   . VAL B 2 15  ? 78.457  107.493 141.797 1.00 127.74 ? 15  VAL H O   1 
ATOM 899  C CB  . VAL B 2 15  ? 78.303  107.650 138.488 1.00 127.74 ? 15  VAL H CB  1 
ATOM 900  C CG1 . VAL B 2 15  ? 79.731  107.289 138.872 1.00 127.74 ? 15  VAL H CG1 1 
ATOM 901  C CG2 . VAL B 2 15  ? 77.562  106.450 137.919 1.00 127.74 ? 15  VAL H CG2 1 
ATOM 902  N N   . LYS B 2 16  ? 76.704  106.357 140.954 1.00 132.31 ? 16  LYS H N   1 
ATOM 903  C CA  . LYS B 2 16  ? 76.624  105.401 142.049 1.00 132.31 ? 16  LYS H CA  1 
ATOM 904  C C   . LYS B 2 16  ? 76.831  103.988 141.523 1.00 132.31 ? 16  LYS H C   1 
ATOM 905  O O   . LYS B 2 16  ? 76.451  103.674 140.390 1.00 132.31 ? 16  LYS H O   1 
ATOM 906  C CB  . LYS B 2 16  ? 75.276  105.499 142.775 1.00 132.31 ? 16  LYS H CB  1 
ATOM 907  C CG  . LYS B 2 16  ? 74.081  105.086 141.932 1.00 132.31 ? 16  LYS H CG  1 
ATOM 908  C CD  . LYS B 2 16  ? 72.867  104.794 142.798 1.00 132.31 ? 16  LYS H CD  1 
ATOM 909  C CE  . LYS B 2 16  ? 71.615  104.636 141.952 1.00 132.31 ? 16  LYS H CE  1 
ATOM 910  N NZ  . LYS B 2 16  ? 71.894  103.901 140.687 1.00 132.31 ? 16  LYS H NZ  1 
ATOM 911  N N   . SER B 2 17  ? 77.442  103.143 142.358 1.00 134.37 ? 17  SER H N   1 
ATOM 912  C CA  . SER B 2 17  ? 77.700  101.740 142.047 1.00 134.37 ? 17  SER H CA  1 
ATOM 913  C C   . SER B 2 17  ? 78.447  101.576 140.729 1.00 134.37 ? 17  SER H C   1 
ATOM 914  O O   . SER B 2 17  ? 79.227  102.449 140.337 1.00 134.37 ? 17  SER H O   1 
ATOM 915  C CB  . SER B 2 17  ? 76.389  100.948 142.011 1.00 134.37 ? 17  SER H CB  1 
ATOM 916  O OG  . SER B 2 17  ? 75.594  101.316 140.897 1.00 134.37 ? 17  SER H OG  1 
ATOM 917  N N   . GLY B 2 18  ? 78.217  100.459 140.043 1.00 133.47 ? 18  GLY H N   1 
ATOM 918  C CA  . GLY B 2 18  ? 78.868  100.207 138.774 1.00 133.47 ? 18  GLY H CA  1 
ATOM 919  C C   . GLY B 2 18  ? 77.940  100.324 137.583 1.00 133.47 ? 18  GLY H C   1 
ATOM 920  O O   . GLY B 2 18  ? 77.127  99.429  137.331 1.00 133.47 ? 18  GLY H O   1 
ATOM 921  N N   . THR B 2 19  ? 78.056  101.419 136.842 1.00 139.10 ? 19  THR H N   1 
ATOM 922  C CA  . THR B 2 19  ? 77.259  101.652 135.641 1.00 139.10 ? 19  THR H CA  1 
ATOM 923  C C   . THR B 2 19  ? 78.177  102.254 134.582 1.00 139.10 ? 19  THR H C   1 
ATOM 924  O O   . THR B 2 19  ? 79.405  102.203 134.707 1.00 139.10 ? 19  THR H O   1 
ATOM 925  C CB  . THR B 2 19  ? 76.046  102.554 135.941 1.00 139.10 ? 19  THR H CB  1 
ATOM 926  O OG1 . THR B 2 19  ? 76.498  103.819 136.439 1.00 139.10 ? 19  THR H OG1 1 
ATOM 927  C CG2 . THR B 2 19  ? 75.107  101.911 136.954 1.00 139.10 ? 19  THR H CG2 1 
ATOM 928  N N   . SER B 2 20  ? 77.585  102.818 133.534 1.00 136.70 ? 20  SER H N   1 
ATOM 929  C CA  . SER B 2 20  ? 78.324  103.482 132.471 1.00 136.70 ? 20  SER H CA  1 
ATOM 930  C C   . SER B 2 20  ? 78.195  104.992 132.622 1.00 136.70 ? 20  SER H C   1 
ATOM 931  O O   . SER B 2 20  ? 77.124  105.502 132.968 1.00 136.70 ? 20  SER H O   1 
ATOM 932  C CB  . SER B 2 20  ? 77.816  103.048 131.094 1.00 136.70 ? 20  SER H CB  1 
ATOM 933  O OG  . SER B 2 20  ? 78.263  101.741 130.777 1.00 136.70 ? 20  SER H OG  1 
ATOM 934  N N   . VAL B 2 21  ? 79.292  105.704 132.363 1.00 128.15 ? 21  VAL H N   1 
ATOM 935  C CA  . VAL B 2 21  ? 79.332  107.154 132.475 1.00 128.15 ? 21  VAL H CA  1 
ATOM 936  C C   . VAL B 2 21  ? 79.827  107.736 131.159 1.00 128.15 ? 21  VAL H C   1 
ATOM 937  O O   . VAL B 2 21  ? 80.446  107.053 130.340 1.00 128.15 ? 21  VAL H O   1 
ATOM 938  C CB  . VAL B 2 21  ? 80.223  107.632 133.643 1.00 128.15 ? 21  VAL H CB  1 
ATOM 939  C CG1 . VAL B 2 21  ? 79.770  107.005 134.949 1.00 128.15 ? 21  VAL H CG1 1 
ATOM 940  C CG2 . VAL B 2 21  ? 81.678  107.301 133.367 1.00 128.15 ? 21  VAL H CG2 1 
ATOM 941  N N   . LYS B 2 22  ? 79.542  109.021 130.964 1.00 119.72 ? 22  LYS H N   1 
ATOM 942  C CA  . LYS B 2 22  ? 79.859  109.730 129.727 1.00 119.72 ? 22  LYS H CA  1 
ATOM 943  C C   . LYS B 2 22  ? 80.742  110.928 130.061 1.00 119.72 ? 22  LYS H C   1 
ATOM 944  O O   . LYS B 2 22  ? 80.275  111.908 130.650 1.00 119.72 ? 22  LYS H O   1 
ATOM 945  C CB  . LYS B 2 22  ? 78.582  110.166 129.010 1.00 119.72 ? 22  LYS H CB  1 
ATOM 946  C CG  . LYS B 2 22  ? 77.846  109.045 128.284 1.00 119.72 ? 22  LYS H CG  1 
ATOM 947  C CD  . LYS B 2 22  ? 78.771  108.217 127.403 1.00 119.72 ? 22  LYS H CD  1 
ATOM 948  C CE  . LYS B 2 22  ? 79.434  109.071 126.330 1.00 119.72 ? 22  LYS H CE  1 
ATOM 949  N NZ  . LYS B 2 22  ? 78.594  109.175 125.106 1.00 119.72 ? 22  LYS H NZ  1 
ATOM 950  N N   . LEU B 2 23  ? 82.014  110.848 129.686 1.00 113.09 ? 23  LEU H N   1 
ATOM 951  C CA  . LEU B 2 23  ? 82.951  111.955 129.824 1.00 113.09 ? 23  LEU H CA  1 
ATOM 952  C C   . LEU B 2 23  ? 83.301  112.478 128.439 1.00 113.09 ? 23  LEU H C   1 
ATOM 953  O O   . LEU B 2 23  ? 83.699  111.704 127.563 1.00 113.09 ? 23  LEU H O   1 
ATOM 954  C CB  . LEU B 2 23  ? 84.218  111.520 130.563 1.00 113.09 ? 23  LEU H CB  1 
ATOM 955  C CG  . LEU B 2 23  ? 84.211  111.556 132.094 1.00 113.09 ? 23  LEU H CG  1 
ATOM 956  C CD1 . LEU B 2 23  ? 83.995  112.976 132.590 1.00 113.09 ? 23  LEU H CD1 1 
ATOM 957  C CD2 . LEU B 2 23  ? 83.171  110.613 132.681 1.00 113.09 ? 23  LEU H CD2 1 
ATOM 958  N N   . SER B 2 24  ? 83.156  113.787 128.243 1.00 105.57 ? 24  SER H N   1 
ATOM 959  C CA  . SER B 2 24  ? 83.366  114.400 126.941 1.00 105.57 ? 24  SER H CA  1 
ATOM 960  C C   . SER B 2 24  ? 84.306  115.589 127.065 1.00 105.57 ? 24  SER H C   1 
ATOM 961  O O   . SER B 2 24  ? 84.331  116.280 128.086 1.00 105.57 ? 24  SER H O   1 
ATOM 962  C CB  . SER B 2 24  ? 82.040  114.853 126.315 1.00 105.57 ? 24  SER H CB  1 
ATOM 963  O OG  . SER B 2 24  ? 81.579  116.051 126.912 1.00 105.57 ? 24  SER H OG  1 
ATOM 964  N N   . CYS B 2 25  ? 85.078  115.819 126.004 1.00 103.60 ? 25  CYS H N   1 
ATOM 965  C CA  . CYS B 2 25  ? 85.996  116.948 125.918 1.00 103.60 ? 25  CYS H CA  1 
ATOM 966  C C   . CYS B 2 25  ? 85.648  117.751 124.675 1.00 103.60 ? 25  CYS H C   1 
ATOM 967  O O   . CYS B 2 25  ? 85.707  117.225 123.559 1.00 103.60 ? 25  CYS H O   1 
ATOM 968  C CB  . CYS B 2 25  ? 87.452  116.477 125.865 1.00 103.60 ? 25  CYS H CB  1 
ATOM 969  S SG  . CYS B 2 25  ? 88.676  117.752 126.251 1.00 103.60 ? 25  CYS H SG  1 
ATOM 970  N N   . LYS B 2 26  ? 85.284  119.016 124.866 1.00 107.13 ? 26  LYS H N   1 
ATOM 971  C CA  . LYS B 2 26  ? 84.912  119.893 123.762 1.00 107.13 ? 26  LYS H CA  1 
ATOM 972  C C   . LYS B 2 26  ? 86.148  120.668 123.323 1.00 107.13 ? 26  LYS H C   1 
ATOM 973  O O   . LYS B 2 26  ? 86.666  121.502 124.072 1.00 107.13 ? 26  LYS H O   1 
ATOM 974  C CB  . LYS B 2 26  ? 83.785  120.835 124.176 1.00 107.13 ? 26  LYS H CB  1 
ATOM 975  C CG  . LYS B 2 26  ? 83.396  121.855 123.115 1.00 107.13 ? 26  LYS H CG  1 
ATOM 976  C CD  . LYS B 2 26  ? 83.127  121.194 121.772 1.00 107.13 ? 26  LYS H CD  1 
ATOM 977  C CE  . LYS B 2 26  ? 82.391  122.136 120.834 1.00 107.13 ? 26  LYS H CE  1 
ATOM 978  N NZ  . LYS B 2 26  ? 82.107  121.499 119.519 1.00 107.13 ? 26  LYS H NZ  1 
ATOM 979  N N   . ALA B 2 27  ? 86.618  120.394 122.111 1.00 102.92 ? 27  ALA H N   1 
ATOM 980  C CA  . ALA B 2 27  ? 87.795  121.042 121.552 1.00 102.92 ? 27  ALA H CA  1 
ATOM 981  C C   . ALA B 2 27  ? 87.372  121.969 120.423 1.00 102.92 ? 27  ALA H C   1 
ATOM 982  O O   . ALA B 2 27  ? 86.648  121.555 119.512 1.00 102.92 ? 27  ALA H O   1 
ATOM 983  C CB  . ALA B 2 27  ? 88.798  120.007 121.041 1.00 102.92 ? 27  ALA H CB  1 
ATOM 984  N N   . SER B 2 28  ? 87.823  123.219 120.486 1.00 100.54 ? 28  SER H N   1 
ATOM 985  C CA  . SER B 2 28  ? 87.477  124.216 119.483 1.00 100.54 ? 28  SER H CA  1 
ATOM 986  C C   . SER B 2 28  ? 88.712  125.029 119.132 1.00 100.54 ? 28  SER H C   1 
ATOM 987  O O   . SER B 2 28  ? 89.339  125.620 120.016 1.00 100.54 ? 28  SER H O   1 
ATOM 988  C CB  . SER B 2 28  ? 86.362  125.140 119.984 1.00 100.54 ? 28  SER H CB  1 
ATOM 989  O OG  . SER B 2 28  ? 86.811  125.937 121.067 1.00 100.54 ? 28  SER H OG  1 
ATOM 990  N N   . GLY B 2 29  ? 89.053  125.061 117.848 1.00 96.47  ? 29  GLY H N   1 
ATOM 991  C CA  . GLY B 2 29  ? 90.158  125.860 117.365 1.00 96.47  ? 29  GLY H CA  1 
ATOM 992  C C   . GLY B 2 29  ? 91.329  125.102 116.774 1.00 96.47  ? 29  GLY H C   1 
ATOM 993  O O   . GLY B 2 29  ? 92.356  125.726 116.482 1.00 96.47  ? 29  GLY H O   1 
ATOM 994  N N   . TYR B 2 30  ? 91.220  123.789 116.587 1.00 88.60  ? 30  TYR H N   1 
ATOM 995  C CA  . TYR B 2 30  ? 92.297  123.033 115.965 1.00 88.60  ? 30  TYR H CA  1 
ATOM 996  C C   . TYR B 2 30  ? 91.714  121.826 115.245 1.00 88.60  ? 30  TYR H C   1 
ATOM 997  O O   . TYR B 2 30  ? 90.590  121.398 115.516 1.00 88.60  ? 30  TYR H O   1 
ATOM 998  C CB  . TYR B 2 30  ? 93.353  122.601 116.991 1.00 88.60  ? 30  TYR H CB  1 
ATOM 999  C CG  . TYR B 2 30  ? 93.038  121.322 117.732 1.00 88.60  ? 30  TYR H CG  1 
ATOM 1000 C CD1 . TYR B 2 30  ? 92.225  121.330 118.855 1.00 88.60  ? 30  TYR H CD1 1 
ATOM 1001 C CD2 . TYR B 2 30  ? 93.578  120.108 117.324 1.00 88.60  ? 30  TYR H CD2 1 
ATOM 1002 C CE1 . TYR B 2 30  ? 91.944  120.165 119.539 1.00 88.60  ? 30  TYR H CE1 1 
ATOM 1003 C CE2 . TYR B 2 30  ? 93.301  118.938 118.002 1.00 88.60  ? 30  TYR H CE2 1 
ATOM 1004 C CZ  . TYR B 2 30  ? 92.484  118.973 119.109 1.00 88.60  ? 30  TYR H CZ  1 
ATOM 1005 O OH  . TYR B 2 30  ? 92.206  117.812 119.790 1.00 88.60  ? 30  TYR H OH  1 
ATOM 1006 N N   . SER B 2 31  ? 92.501  121.282 114.321 1.00 89.15  ? 31  SER H N   1 
ATOM 1007 C CA  . SER B 2 31  ? 92.085  120.171 113.480 1.00 89.15  ? 31  SER H CA  1 
ATOM 1008 C C   . SER B 2 31  ? 92.812  118.895 113.884 1.00 89.15  ? 31  SER H C   1 
ATOM 1009 O O   . SER B 2 31  ? 93.938  118.931 114.387 1.00 89.15  ? 31  SER H O   1 
ATOM 1010 C CB  . SER B 2 31  ? 92.352  120.472 112.003 1.00 89.15  ? 31  SER H CB  1 
ATOM 1011 O OG  . SER B 2 31  ? 93.708  120.824 111.793 1.00 89.15  ? 31  SER H OG  1 
ATOM 1012 N N   . PHE B 2 32  ? 92.154  117.762 113.647 1.00 89.93  ? 32  PHE H N   1 
ATOM 1013 C CA  . PHE B 2 32  ? 92.678  116.444 113.980 1.00 89.93  ? 32  PHE H CA  1 
ATOM 1014 C C   . PHE B 2 32  ? 93.635  115.896 112.926 1.00 89.93  ? 32  PHE H C   1 
ATOM 1015 O O   . PHE B 2 32  ? 93.895  114.687 112.921 1.00 89.93  ? 32  PHE H O   1 
ATOM 1016 C CB  . PHE B 2 32  ? 91.523  115.460 114.182 1.00 89.93  ? 32  PHE H CB  1 
ATOM 1017 C CG  . PHE B 2 32  ? 90.863  115.564 115.525 1.00 89.93  ? 32  PHE H CG  1 
ATOM 1018 C CD1 . PHE B 2 32  ? 91.616  115.566 116.685 1.00 89.93  ? 32  PHE H CD1 1 
ATOM 1019 C CD2 . PHE B 2 32  ? 89.486  115.664 115.627 1.00 89.93  ? 32  PHE H CD2 1 
ATOM 1020 C CE1 . PHE B 2 32  ? 91.008  115.660 117.921 1.00 89.93  ? 32  PHE H CE1 1 
ATOM 1021 C CE2 . PHE B 2 32  ? 88.873  115.761 116.859 1.00 89.93  ? 32  PHE H CE2 1 
ATOM 1022 C CZ  . PHE B 2 32  ? 89.635  115.759 118.007 1.00 89.93  ? 32  PHE H CZ  1 
ATOM 1023 N N   . THR B 2 33  ? 94.157  116.744 112.036 1.00 85.15  ? 33  THR H N   1 
ATOM 1024 C CA  . THR B 2 33  ? 94.976  116.247 110.934 1.00 85.15  ? 33  THR H CA  1 
ATOM 1025 C C   . THR B 2 33  ? 96.264  115.601 111.432 1.00 85.15  ? 33  THR H C   1 
ATOM 1026 O O   . THR B 2 33  ? 96.686  114.563 110.910 1.00 85.15  ? 33  THR H O   1 
ATOM 1027 C CB  . THR B 2 33  ? 95.278  117.379 109.948 1.00 85.15  ? 33  THR H CB  1 
ATOM 1028 O OG1 . THR B 2 33  ? 96.171  116.907 108.931 1.00 85.15  ? 33  THR H OG1 1 
ATOM 1029 C CG2 . THR B 2 33  ? 95.892  118.583 110.655 1.00 85.15  ? 33  THR H CG2 1 
ATOM 1030 N N   . ASP B 2 34  ? 96.906  116.197 112.436 1.00 75.95  ? 34  ASP H N   1 
ATOM 1031 C CA  . ASP B 2 34  ? 98.168  115.680 112.952 1.00 75.95  ? 34  ASP H CA  1 
ATOM 1032 C C   . ASP B 2 34  ? 98.228  115.606 114.471 1.00 75.95  ? 34  ASP H C   1 
ATOM 1033 O O   . ASP B 2 34  ? 98.967  114.765 114.996 1.00 75.95  ? 34  ASP H O   1 
ATOM 1034 C CB  . ASP B 2 34  ? 99.334  116.540 112.434 1.00 75.95  ? 34  ASP H CB  1 
ATOM 1035 C CG  . ASP B 2 34  ? 100.693 115.889 112.632 1.00 75.95  ? 34  ASP H CG  1 
ATOM 1036 O OD1 . ASP B 2 34  ? 101.105 115.661 113.787 1.00 75.95  ? 34  ASP H OD1 1 
ATOM 1037 O OD2 . ASP B 2 34  ? 101.357 115.600 111.615 1.00 75.95  ? 34  ASP H OD2 1 
ATOM 1038 N N   . HIS B 2 35  ? 97.453  116.412 115.190 1.00 69.91  ? 35  HIS H N   1 
ATOM 1039 C CA  . HIS B 2 35  ? 97.525  116.433 116.641 1.00 69.91  ? 35  HIS H CA  1 
ATOM 1040 C C   . HIS B 2 35  ? 96.949  115.150 117.234 1.00 69.91  ? 35  HIS H C   1 
ATOM 1041 O O   . HIS B 2 35  ? 96.155  114.442 116.610 1.00 69.91  ? 35  HIS H O   1 
ATOM 1042 C CB  . HIS B 2 35  ? 96.774  117.643 117.197 1.00 69.91  ? 35  HIS H CB  1 
ATOM 1043 C CG  . HIS B 2 35  ? 97.347  118.959 116.774 1.00 69.91  ? 35  HIS H CG  1 
ATOM 1044 N ND1 . HIS B 2 35  ? 97.364  119.376 115.460 1.00 69.91  ? 35  HIS H ND1 1 
ATOM 1045 C CD2 . HIS B 2 35  ? 97.920  119.953 117.492 1.00 69.91  ? 35  HIS H CD2 1 
ATOM 1046 C CE1 . HIS B 2 35  ? 97.924  120.570 115.387 1.00 69.91  ? 35  HIS H CE1 1 
ATOM 1047 N NE2 . HIS B 2 35  ? 98.270  120.943 116.606 1.00 69.91  ? 35  HIS H NE2 1 
ATOM 1048 N N   . SER B 2 36  ? 97.367  114.856 118.462 1.00 66.79  ? 36  SER H N   1 
ATOM 1049 C CA  . SER B 2 36  ? 96.869  113.717 119.217 1.00 66.79  ? 36  SER H CA  1 
ATOM 1050 C C   . SER B 2 36  ? 96.249  114.208 120.517 1.00 66.79  ? 36  SER H C   1 
ATOM 1051 O O   . SER B 2 36  ? 96.847  115.016 121.233 1.00 66.79  ? 36  SER H O   1 
ATOM 1052 C CB  . SER B 2 36  ? 97.988  112.715 119.515 1.00 66.79  ? 36  SER H CB  1 
ATOM 1053 O OG  . SER B 2 36  ? 99.017  113.314 120.282 1.00 66.79  ? 36  SER H OG  1 
ATOM 1054 N N   . LEU B 2 37  ? 95.052  113.714 120.819 1.00 68.64  ? 37  LEU H N   1 
ATOM 1055 C CA  . LEU B 2 37  ? 94.294  114.132 121.994 1.00 68.64  ? 37  LEU H CA  1 
ATOM 1056 C C   . LEU B 2 37  ? 94.464  113.072 123.075 1.00 68.64  ? 37  LEU H C   1 
ATOM 1057 O O   . LEU B 2 37  ? 93.959  111.954 122.941 1.00 68.64  ? 37  LEU H O   1 
ATOM 1058 C CB  . LEU B 2 37  ? 92.823  114.344 121.637 1.00 68.64  ? 37  LEU H CB  1 
ATOM 1059 C CG  . LEU B 2 37  ? 91.874  114.954 122.673 1.00 68.64  ? 37  LEU H CG  1 
ATOM 1060 C CD1 . LEU B 2 37  ? 90.732  115.663 121.967 1.00 68.64  ? 37  LEU H CD1 1 
ATOM 1061 C CD2 . LEU B 2 37  ? 91.320  113.901 123.621 1.00 68.64  ? 37  LEU H CD2 1 
ATOM 1062 N N   . HIS B 2 38  ? 95.168  113.429 124.145 1.00 69.01  ? 38  HIS H N   1 
ATOM 1063 C CA  . HIS B 2 38  ? 95.439  112.518 125.245 1.00 69.01  ? 38  HIS H CA  1 
ATOM 1064 C C   . HIS B 2 38  ? 94.335  112.597 126.296 1.00 69.01  ? 38  HIS H C   1 
ATOM 1065 O O   . HIS B 2 38  ? 93.499  113.502 126.295 1.00 69.01  ? 38  HIS H O   1 
ATOM 1066 C CB  . HIS B 2 38  ? 96.798  112.833 125.866 1.00 69.01  ? 38  HIS H CB  1 
ATOM 1067 C CG  . HIS B 2 38  ? 97.940  112.705 124.909 1.00 69.01  ? 38  HIS H CG  1 
ATOM 1068 N ND1 . HIS B 2 38  ? 98.559  111.502 124.646 1.00 69.01  ? 38  HIS H ND1 1 
ATOM 1069 C CD2 . HIS B 2 38  ? 98.565  113.626 124.138 1.00 69.01  ? 38  HIS H CD2 1 
ATOM 1070 C CE1 . HIS B 2 38  ? 99.523  111.689 123.762 1.00 69.01  ? 38  HIS H CE1 1 
ATOM 1071 N NE2 . HIS B 2 38  ? 99.548  112.969 123.438 1.00 69.01  ? 38  HIS H NE2 1 
ATOM 1072 N N   . TRP B 2 39  ? 94.339  111.626 127.206 1.00 80.84  ? 39  TRP H N   1 
ATOM 1073 C CA  . TRP B 2 39  ? 93.322  111.506 128.247 1.00 80.84  ? 39  TRP H CA  1 
ATOM 1074 C C   . TRP B 2 39  ? 93.966  111.213 129.597 1.00 80.84  ? 39  TRP H C   1 
ATOM 1075 O O   . TRP B 2 39  ? 93.581  110.286 130.311 1.00 80.84  ? 39  TRP H O   1 
ATOM 1076 C CB  . TRP B 2 39  ? 92.303  110.431 127.884 1.00 80.84  ? 39  TRP H CB  1 
ATOM 1077 C CG  . TRP B 2 39  ? 91.109  110.974 127.170 1.00 80.84  ? 39  TRP H CG  1 
ATOM 1078 C CD1 . TRP B 2 39  ? 90.784  110.786 125.861 1.00 80.84  ? 39  TRP H CD1 1 
ATOM 1079 C CD2 . TRP B 2 39  ? 90.081  111.801 127.725 1.00 80.84  ? 39  TRP H CD2 1 
ATOM 1080 N NE1 . TRP B 2 39  ? 89.616  111.443 125.564 1.00 80.84  ? 39  TRP H NE1 1 
ATOM 1081 C CE2 . TRP B 2 39  ? 89.164  112.075 126.693 1.00 80.84  ? 39  TRP H CE2 1 
ATOM 1082 C CE3 . TRP B 2 39  ? 89.847  112.337 128.994 1.00 80.84  ? 39  TRP H CE3 1 
ATOM 1083 C CZ2 . TRP B 2 39  ? 88.032  112.859 126.890 1.00 80.84  ? 39  TRP H CZ2 1 
ATOM 1084 C CZ3 . TRP B 2 39  ? 88.723  113.115 129.188 1.00 80.84  ? 39  TRP H CZ3 1 
ATOM 1085 C CH2 . TRP B 2 39  ? 87.830  113.369 128.142 1.00 80.84  ? 39  TRP H CH2 1 
ATOM 1086 N N   . VAL B 2 40  ? 94.977  112.007 129.956 1.00 75.19  ? 40  VAL H N   1 
ATOM 1087 C CA  . VAL B 2 40  ? 95.664  111.813 131.225 1.00 75.19  ? 40  VAL H CA  1 
ATOM 1088 C C   . VAL B 2 40  ? 94.693  112.004 132.391 1.00 75.19  ? 40  VAL H C   1 
ATOM 1089 O O   . VAL B 2 40  ? 93.751  112.803 132.327 1.00 75.19  ? 40  VAL H O   1 
ATOM 1090 C CB  . VAL B 2 40  ? 96.860  112.776 131.329 1.00 75.19  ? 40  VAL H CB  1 
ATOM 1091 C CG1 . VAL B 2 40  ? 96.387  114.220 131.366 1.00 75.19  ? 40  VAL H CG1 1 
ATOM 1092 C CG2 . VAL B 2 40  ? 97.711  112.460 132.547 1.00 75.19  ? 40  VAL H CG2 1 
ATOM 1093 N N   . LYS B 2 41  ? 94.915  111.242 133.463 1.00 80.67  ? 41  LYS H N   1 
ATOM 1094 C CA  . LYS B 2 41  ? 94.144  111.366 134.691 1.00 80.67  ? 41  LYS H CA  1 
ATOM 1095 C C   . LYS B 2 41  ? 95.098  111.547 135.861 1.00 80.67  ? 41  LYS H C   1 
ATOM 1096 O O   . LYS B 2 41  ? 96.256  111.128 135.807 1.00 80.67  ? 41  LYS H O   1 
ATOM 1097 C CB  . LYS B 2 41  ? 93.250  110.145 134.942 1.00 80.67  ? 41  LYS H CB  1 
ATOM 1098 C CG  . LYS B 2 41  ? 94.013  108.868 135.246 1.00 80.67  ? 41  LYS H CG  1 
ATOM 1099 C CD  . LYS B 2 41  ? 93.070  107.692 135.440 1.00 80.67  ? 41  LYS H CD  1 
ATOM 1100 C CE  . LYS B 2 41  ? 92.274  107.826 136.727 1.00 80.67  ? 41  LYS H CE  1 
ATOM 1101 N NZ  . LYS B 2 41  ? 93.144  107.736 137.932 1.00 80.67  ? 41  LYS H NZ  1 
ATOM 1102 N N   . GLN B 2 42  ? 94.600  112.178 136.923 1.00 87.77  ? 42  GLN H N   1 
ATOM 1103 C CA  . GLN B 2 42  ? 95.425  112.529 138.071 1.00 87.77  ? 42  GLN H CA  1 
ATOM 1104 C C   . GLN B 2 42  ? 95.085  111.730 139.322 1.00 87.77  ? 42  GLN H C   1 
ATOM 1105 O O   . GLN B 2 42  ? 95.865  111.741 140.279 1.00 87.77  ? 42  GLN H O   1 
ATOM 1106 C CB  . GLN B 2 42  ? 95.308  114.025 138.369 1.00 87.77  ? 42  GLN H CB  1 
ATOM 1107 C CG  . GLN B 2 42  ? 96.490  114.586 139.140 1.00 87.77  ? 42  GLN H CG  1 
ATOM 1108 C CD  . GLN B 2 42  ? 96.092  115.688 140.094 1.00 87.77  ? 42  GLN H CD  1 
ATOM 1109 O OE1 . GLN B 2 42  ? 96.695  116.761 140.108 1.00 87.77  ? 42  GLN H OE1 1 
ATOM 1110 N NE2 . GLN B 2 42  ? 95.065  115.435 140.893 1.00 87.77  ? 42  GLN H NE2 1 
ATOM 1111 N N   . SER B 2 43  ? 93.946  111.041 139.341 1.00 95.98  ? 43  SER H N   1 
ATOM 1112 C CA  . SER B 2 43  ? 93.408  110.424 140.560 1.00 95.98  ? 43  SER H CA  1 
ATOM 1113 C C   . SER B 2 43  ? 93.305  111.534 141.606 1.00 95.98  ? 43  SER H C   1 
ATOM 1114 O O   . SER B 2 43  ? 92.892  112.649 141.261 1.00 95.98  ? 43  SER H O   1 
ATOM 1115 C CB  . SER B 2 43  ? 94.252  109.219 140.955 1.00 95.98  ? 43  SER H CB  1 
ATOM 1116 O OG  . SER B 2 43  ? 93.773  108.634 142.154 1.00 95.98  ? 43  SER H OG  1 
ATOM 1117 N N   . HIS B 2 44  ? 93.698  111.303 142.857 1.00 104.32 ? 44  HIS H N   1 
ATOM 1118 C CA  . HIS B 2 44  ? 93.488  112.293 143.905 1.00 104.32 ? 44  HIS H CA  1 
ATOM 1119 C C   . HIS B 2 44  ? 94.803  112.638 144.584 1.00 104.32 ? 44  HIS H C   1 
ATOM 1120 O O   . HIS B 2 44  ? 95.578  111.745 144.939 1.00 104.32 ? 44  HIS H O   1 
ATOM 1121 C CB  . HIS B 2 44  ? 92.478  111.791 144.945 1.00 104.32 ? 44  HIS H CB  1 
ATOM 1122 C CG  . HIS B 2 44  ? 92.254  112.742 146.080 1.00 104.32 ? 44  HIS H CG  1 
ATOM 1123 N ND1 . HIS B 2 44  ? 93.164  112.916 147.100 1.00 104.32 ? 44  HIS H ND1 1 
ATOM 1124 C CD2 . HIS B 2 44  ? 91.223  113.578 146.350 1.00 104.32 ? 44  HIS H CD2 1 
ATOM 1125 C CE1 . HIS B 2 44  ? 92.703  113.815 147.951 1.00 104.32 ? 44  HIS H CE1 1 
ATOM 1126 N NE2 . HIS B 2 44  ? 91.527  114.232 147.519 1.00 104.32 ? 44  HIS H NE2 1 
ATOM 1127 N N   . GLY B 2 45  ? 95.043  113.935 144.760 1.00 105.33 ? 45  GLY H N   1 
ATOM 1128 C CA  . GLY B 2 45  ? 96.129  114.419 145.591 1.00 105.33 ? 45  GLY H CA  1 
ATOM 1129 C C   . GLY B 2 45  ? 97.516  114.328 144.990 1.00 105.33 ? 45  GLY H C   1 
ATOM 1130 O O   . GLY B 2 45  ? 98.118  115.351 144.650 1.00 105.33 ? 45  GLY H O   1 
ATOM 1131 N N   . GLU B 2 46  ? 98.035  113.111 144.855 1.00 104.01 ? 46  GLU H N   1 
ATOM 1132 C CA  . GLU B 2 46  ? 99.419  112.893 144.462 1.00 104.01 ? 46  GLU H CA  1 
ATOM 1133 C C   . GLU B 2 46  ? 99.482  111.983 143.246 1.00 104.01 ? 46  GLU H C   1 
ATOM 1134 O O   . GLU B 2 46  ? 98.652  111.081 143.092 1.00 104.01 ? 46  GLU H O   1 
ATOM 1135 C CB  . GLU B 2 46  ? 100.235 112.283 145.612 1.00 104.01 ? 46  GLU H CB  1 
ATOM 1136 C CG  . GLU B 2 46  ? 99.951  112.886 146.982 1.00 104.01 ? 46  GLU H CG  1 
ATOM 1137 C CD  . GLU B 2 46  ? 98.770  112.238 147.681 1.00 104.01 ? 46  GLU H CD  1 
ATOM 1138 O OE1 . GLU B 2 46  ? 98.043  111.458 147.031 1.00 104.01 ? 46  GLU H OE1 1 
ATOM 1139 O OE2 . GLU B 2 46  ? 98.568  112.511 148.883 1.00 104.01 ? 46  GLU H OE2 1 
ATOM 1140 N N   . SER B 2 47  ? 100.462 112.247 142.376 1.00 91.92  ? 47  SER H N   1 
ATOM 1141 C CA  . SER B 2 47  ? 100.759 111.432 141.201 1.00 91.92  ? 47  SER H CA  1 
ATOM 1142 C C   . SER B 2 47  ? 99.661  111.540 140.151 1.00 91.92  ? 47  SER H C   1 
ATOM 1143 O O   . SER B 2 47  ? 98.537  111.947 140.455 1.00 91.92  ? 47  SER H O   1 
ATOM 1144 C CB  . SER B 2 47  ? 100.978 109.967 141.591 1.00 91.92  ? 47  SER H CB  1 
ATOM 1145 O OG  . SER B 2 47  ? 99.741  109.299 141.774 1.00 91.92  ? 47  SER H OG  1 
ATOM 1146 N N   . LEU B 2 48  ? 99.986  111.198 138.907 1.00 78.11  ? 48  LEU H N   1 
ATOM 1147 C CA  . LEU B 2 48  ? 99.012  111.180 137.826 1.00 78.11  ? 48  LEU H CA  1 
ATOM 1148 C C   . LEU B 2 48  ? 99.385  110.080 136.843 1.00 78.11  ? 48  LEU H C   1 
ATOM 1149 O O   . LEU B 2 48  ? 100.552 109.703 136.716 1.00 78.11  ? 48  LEU H O   1 
ATOM 1150 C CB  . LEU B 2 48  ? 98.916  112.543 137.123 1.00 78.11  ? 48  LEU H CB  1 
ATOM 1151 C CG  . LEU B 2 48  ? 100.041 113.023 136.208 1.00 78.11  ? 48  LEU H CG  1 
ATOM 1152 C CD1 . LEU B 2 48  ? 99.547  114.182 135.364 1.00 78.11  ? 48  LEU H CD1 1 
ATOM 1153 C CD2 . LEU B 2 48  ? 101.244 113.453 137.025 1.00 78.11  ? 48  LEU H CD2 1 
ATOM 1154 N N   . GLU B 2 49  ? 98.374  109.565 136.146 1.00 81.96  ? 49  GLU H N   1 
ATOM 1155 C CA  . GLU B 2 49  ? 98.525  108.379 135.316 1.00 81.96  ? 49  GLU H CA  1 
ATOM 1156 C C   . GLU B 2 49  ? 98.016  108.644 133.908 1.00 81.96  ? 49  GLU H C   1 
ATOM 1157 O O   . GLU B 2 49  ? 97.168  109.512 133.686 1.00 81.96  ? 49  GLU H O   1 
ATOM 1158 C CB  . GLU B 2 49  ? 97.776  107.180 135.915 1.00 81.96  ? 49  GLU H CB  1 
ATOM 1159 C CG  . GLU B 2 49  ? 98.500  106.502 137.066 1.00 81.96  ? 49  GLU H CG  1 
ATOM 1160 C CD  . GLU B 2 49  ? 98.216  107.161 138.403 1.00 81.96  ? 49  GLU H CD  1 
ATOM 1161 O OE1 . GLU B 2 49  ? 97.028  107.382 138.719 1.00 81.96  ? 49  GLU H OE1 1 
ATOM 1162 O OE2 . GLU B 2 49  ? 99.181  107.456 139.139 1.00 81.96  ? 49  GLU H OE2 1 
ATOM 1163 N N   . TRP B 2 50  ? 98.543  107.877 132.959 1.00 74.40  ? 50  TRP H N   1 
ATOM 1164 C CA  . TRP B 2 50  ? 98.167  107.987 131.560 1.00 74.40  ? 50  TRP H CA  1 
ATOM 1165 C C   . TRP B 2 50  ? 97.097  106.954 131.210 1.00 74.40  ? 50  TRP H C   1 
ATOM 1166 O O   . TRP B 2 50  ? 97.007  105.885 131.819 1.00 74.40  ? 50  TRP H O   1 
ATOM 1167 C CB  . TRP B 2 50  ? 99.395  107.798 130.673 1.00 74.40  ? 50  TRP H CB  1 
ATOM 1168 C CG  . TRP B 2 50  ? 99.207  108.249 129.271 1.00 74.40  ? 50  TRP H CG  1 
ATOM 1169 C CD1 . TRP B 2 50  ? 98.929  109.512 128.848 1.00 74.40  ? 50  TRP H CD1 1 
ATOM 1170 C CD2 . TRP B 2 50  ? 99.280  107.437 128.096 1.00 74.40  ? 50  TRP H CD2 1 
ATOM 1171 N NE1 . TRP B 2 50  ? 98.826  109.540 127.480 1.00 74.40  ? 50  TRP H NE1 1 
ATOM 1172 C CE2 . TRP B 2 50  ? 99.037  108.277 126.995 1.00 74.40  ? 50  TRP H CE2 1 
ATOM 1173 C CE3 . TRP B 2 50  ? 99.529  106.081 127.869 1.00 74.40  ? 50  TRP H CE3 1 
ATOM 1174 C CZ2 . TRP B 2 50  ? 99.035  107.806 125.688 1.00 74.40  ? 50  TRP H CZ2 1 
ATOM 1175 C CZ3 . TRP B 2 50  ? 99.526  105.616 126.570 1.00 74.40  ? 50  TRP H CZ3 1 
ATOM 1176 C CH2 . TRP B 2 50  ? 99.280  106.476 125.496 1.00 74.40  ? 50  TRP H CH2 1 
ATOM 1177 N N   . ILE B 2 51  ? 96.280  107.283 130.209 1.00 77.67  ? 51  ILE H N   1 
ATOM 1178 C CA  . ILE B 2 51  ? 95.194  106.397 129.798 1.00 77.67  ? 51  ILE H CA  1 
ATOM 1179 C C   . ILE B 2 51  ? 95.331  106.017 128.329 1.00 77.67  ? 51  ILE H C   1 
ATOM 1180 O O   . ILE B 2 51  ? 95.427  104.832 127.992 1.00 77.67  ? 51  ILE H O   1 
ATOM 1181 C CB  . ILE B 2 51  ? 93.820  107.035 130.066 1.00 77.67  ? 51  ILE H CB  1 
ATOM 1182 C CG1 . ILE B 2 51  ? 93.549  107.106 131.569 1.00 77.67  ? 51  ILE H CG1 1 
ATOM 1183 C CG2 . ILE B 2 51  ? 92.723  106.247 129.369 1.00 77.67  ? 51  ILE H CG2 1 
ATOM 1184 C CD1 . ILE B 2 51  ? 92.270  107.830 131.920 1.00 77.67  ? 51  ILE H CD1 1 
ATOM 1185 N N   . GLY B 2 52  ? 95.326  107.006 127.446 1.00 77.85  ? 52  GLY H N   1 
ATOM 1186 C CA  . GLY B 2 52  ? 95.411  106.728 126.027 1.00 77.85  ? 52  GLY H CA  1 
ATOM 1187 C C   . GLY B 2 52  ? 95.282  107.999 125.218 1.00 77.85  ? 52  GLY H C   1 
ATOM 1188 O O   . GLY B 2 52  ? 95.200  109.106 125.759 1.00 77.85  ? 52  GLY H O   1 
ATOM 1189 N N   . TYR B 2 53  ? 95.266  107.816 123.899 1.00 77.04  ? 53  TYR H N   1 
ATOM 1190 C CA  . TYR B 2 53  ? 95.160  108.940 122.981 1.00 77.04  ? 53  TYR H CA  1 
ATOM 1191 C C   . TYR B 2 53  ? 94.542  108.465 121.675 1.00 77.04  ? 53  TYR H C   1 
ATOM 1192 O O   . TYR B 2 53  ? 94.459  107.266 121.399 1.00 77.04  ? 53  TYR H O   1 
ATOM 1193 C CB  . TYR B 2 53  ? 96.528  109.606 122.752 1.00 77.04  ? 53  TYR H CB  1 
ATOM 1194 C CG  . TYR B 2 53  ? 97.507  108.836 121.882 1.00 77.04  ? 53  TYR H CG  1 
ATOM 1195 C CD1 . TYR B 2 53  ? 97.394  108.831 120.497 1.00 77.04  ? 53  TYR H CD1 1 
ATOM 1196 C CD2 . TYR B 2 53  ? 98.556  108.130 122.450 1.00 77.04  ? 53  TYR H CD2 1 
ATOM 1197 C CE1 . TYR B 2 53  ? 98.289  108.137 119.710 1.00 77.04  ? 53  TYR H CE1 1 
ATOM 1198 C CE2 . TYR B 2 53  ? 99.456  107.434 121.670 1.00 77.04  ? 53  TYR H CE2 1 
ATOM 1199 C CZ  . TYR B 2 53  ? 99.317  107.440 120.301 1.00 77.04  ? 53  TYR H CZ  1 
ATOM 1200 O OH  . TYR B 2 53  ? 100.211 106.747 119.519 1.00 77.04  ? 53  TYR H OH  1 
ATOM 1201 N N   . PHE B 2 54  ? 94.102  109.431 120.871 1.00 79.39  ? 54  PHE H N   1 
ATOM 1202 C CA  . PHE B 2 54  ? 93.533  109.172 119.552 1.00 79.39  ? 54  PHE H CA  1 
ATOM 1203 C C   . PHE B 2 54  ? 94.247  110.058 118.541 1.00 79.39  ? 54  PHE H C   1 
ATOM 1204 O O   . PHE B 2 54  ? 94.105  111.285 118.578 1.00 79.39  ? 54  PHE H O   1 
ATOM 1205 C CB  . PHE B 2 54  ? 92.027  109.435 119.534 1.00 79.39  ? 54  PHE H CB  1 
ATOM 1206 C CG  . PHE B 2 54  ? 91.435  109.469 118.153 1.00 79.39  ? 54  PHE H CG  1 
ATOM 1207 C CD1 . PHE B 2 54  ? 91.118  108.295 117.493 1.00 79.39  ? 54  PHE H CD1 1 
ATOM 1208 C CD2 . PHE B 2 54  ? 91.198  110.675 117.514 1.00 79.39  ? 54  PHE H CD2 1 
ATOM 1209 C CE1 . PHE B 2 54  ? 90.576  108.322 116.223 1.00 79.39  ? 54  PHE H CE1 1 
ATOM 1210 C CE2 . PHE B 2 54  ? 90.657  110.707 116.245 1.00 79.39  ? 54  PHE H CE2 1 
ATOM 1211 C CZ  . PHE B 2 54  ? 90.345  109.529 115.599 1.00 79.39  ? 54  PHE H CZ  1 
ATOM 1212 N N   . SER B 2 55  ? 95.011  109.443 117.643 1.00 79.89  ? 55  SER H N   1 
ATOM 1213 C CA  . SER B 2 55  ? 95.686  110.160 116.568 1.00 79.89  ? 55  SER H CA  1 
ATOM 1214 C C   . SER B 2 55  ? 95.420  109.445 115.252 1.00 79.89  ? 55  SER H C   1 
ATOM 1215 O O   . SER B 2 55  ? 95.705  108.240 115.141 1.00 79.89  ? 55  SER H O   1 
ATOM 1216 C CB  . SER B 2 55  ? 97.188  110.254 116.830 1.00 79.89  ? 55  SER H CB  1 
ATOM 1217 O OG  . SER B 2 55  ? 97.786  108.973 116.790 1.00 79.89  ? 55  SER H OG  1 
ATOM 1218 N N   . PRO B 2 56  ? 94.873  110.122 114.240 1.00 83.50  ? 56  PRO H N   1 
ATOM 1219 C CA  . PRO B 2 56  ? 94.596  109.435 112.967 1.00 83.50  ? 56  PRO H CA  1 
ATOM 1220 C C   . PRO B 2 56  ? 95.840  108.926 112.261 1.00 83.50  ? 56  PRO H C   1 
ATOM 1221 O O   . PRO B 2 56  ? 95.739  108.007 111.438 1.00 83.50  ? 56  PRO H O   1 
ATOM 1222 C CB  . PRO B 2 56  ? 93.877  110.508 112.136 1.00 83.50  ? 56  PRO H CB  1 
ATOM 1223 C CG  . PRO B 2 56  ? 93.413  111.529 113.122 1.00 83.50  ? 56  PRO H CG  1 
ATOM 1224 C CD  . PRO B 2 56  ? 94.402  111.515 114.239 1.00 83.50  ? 56  PRO H CD  1 
ATOM 1225 N N   . ASN B 2 57  ? 97.010  109.489 112.550 1.00 83.58  ? 57  ASN H N   1 
ATOM 1226 C CA  . ASN B 2 57  ? 98.237  109.123 111.855 1.00 83.58  ? 57  ASN H CA  1 
ATOM 1227 C C   . ASN B 2 57  ? 99.020  108.018 112.553 1.00 83.58  ? 57  ASN H C   1 
ATOM 1228 O O   . ASN B 2 57  ? 100.103 107.657 112.080 1.00 83.58  ? 57  ASN H O   1 
ATOM 1229 C CB  . ASN B 2 57  ? 99.130  110.355 111.684 1.00 83.58  ? 57  ASN H CB  1 
ATOM 1230 C CG  . ASN B 2 57  ? 98.499  111.412 110.802 1.00 83.58  ? 57  ASN H CG  1 
ATOM 1231 O OD1 . ASN B 2 57  ? 97.283  111.433 110.614 1.00 83.58  ? 57  ASN H OD1 1 
ATOM 1232 N ND2 . ASN B 2 57  ? 99.324  112.294 110.252 1.00 83.58  ? 57  ASN H ND2 1 
ATOM 1233 N N   . ASN B 2 58  ? 98.509  107.473 113.659 1.00 82.94  ? 58  ASN H N   1 
ATOM 1234 C CA  . ASN B 2 58  ? 99.184  106.390 114.364 1.00 82.94  ? 58  ASN H CA  1 
ATOM 1235 C C   . ASN B 2 58  ? 98.238  105.256 114.739 1.00 82.94  ? 58  ASN H C   1 
ATOM 1236 O O   . ASN B 2 58  ? 98.637  104.357 115.488 1.00 82.94  ? 58  ASN H O   1 
ATOM 1237 C CB  . ASN B 2 58  ? 99.881  106.917 115.623 1.00 82.94  ? 58  ASN H CB  1 
ATOM 1238 C CG  . ASN B 2 58  ? 100.960 107.930 115.309 1.00 82.94  ? 58  ASN H CG  1 
ATOM 1239 O OD1 . ASN B 2 58  ? 100.840 109.106 115.649 1.00 82.94  ? 58  ASN H OD1 1 
ATOM 1240 N ND2 . ASN B 2 58  ? 102.024 107.479 114.656 1.00 82.94  ? 58  ASN H ND2 1 
ATOM 1241 N N   . GLY B 2 59  ? 97.003  105.272 114.246 1.00 87.15  ? 59  GLY H N   1 
ATOM 1242 C CA  . GLY B 2 59  ? 96.052  104.222 114.549 1.00 87.15  ? 59  GLY H CA  1 
ATOM 1243 C C   . GLY B 2 59  ? 94.843  104.719 115.314 1.00 87.15  ? 59  GLY H C   1 
ATOM 1244 O O   . GLY B 2 59  ? 93.711  104.320 115.028 1.00 87.15  ? 59  GLY H O   1 
ATOM 1245 N N   . GLY B 2 60  ? 95.070  105.592 116.292 1.00 88.38  ? 60  GLY H N   1 
ATOM 1246 C CA  . GLY B 2 60  ? 93.982  106.173 117.049 1.00 88.38  ? 60  GLY H CA  1 
ATOM 1247 C C   . GLY B 2 60  ? 93.326  105.254 118.052 1.00 88.38  ? 60  GLY H C   1 
ATOM 1248 O O   . GLY B 2 60  ? 92.269  105.603 118.589 1.00 88.38  ? 60  GLY H O   1 
ATOM 1249 N N   . THR B 2 61  ? 93.911  104.090 118.323 1.00 92.28  ? 61  THR H N   1 
ATOM 1250 C CA  . THR B 2 61  ? 93.338  103.136 119.265 1.00 92.28  ? 61  THR H CA  1 
ATOM 1251 C C   . THR B 2 61  ? 94.436  102.584 120.169 1.00 92.28  ? 61  THR H C   1 
ATOM 1252 O O   . THR B 2 61  ? 94.557  101.372 120.372 1.00 92.28  ? 61  THR H O   1 
ATOM 1253 C CB  . THR B 2 61  ? 92.600  102.015 118.528 1.00 92.28  ? 61  THR H CB  1 
ATOM 1254 O OG1 . THR B 2 61  ? 91.762  102.590 117.519 1.00 92.28  ? 61  THR H OG1 1 
ATOM 1255 C CG2 . THR B 2 61  ? 91.702  101.235 119.484 1.00 92.28  ? 61  THR H CG2 1 
ATOM 1256 N N   . ILE B 2 62  ? 95.269  103.471 120.701 1.00 87.31  ? 62  ILE H N   1 
ATOM 1257 C CA  . ILE B 2 62  ? 96.361  103.079 121.583 1.00 87.31  ? 62  ILE H CA  1 
ATOM 1258 C C   . ILE B 2 62  ? 95.940  103.330 123.023 1.00 87.31  ? 62  ILE H C   1 
ATOM 1259 O O   . ILE B 2 62  ? 95.542  104.445 123.380 1.00 87.31  ? 62  ILE H O   1 
ATOM 1260 C CB  . ILE B 2 62  ? 97.650  103.845 121.243 1.00 87.31  ? 62  ILE H CB  1 
ATOM 1261 C CG1 . ILE B 2 62  ? 98.082  103.562 119.803 1.00 87.31  ? 62  ILE H CG1 1 
ATOM 1262 C CG2 . ILE B 2 62  ? 98.757  103.474 122.215 1.00 87.31  ? 62  ILE H CG2 1 
ATOM 1263 C CD1 . ILE B 2 62  ? 97.622  104.602 118.802 1.00 87.31  ? 62  ILE H CD1 1 
ATOM 1264 N N   . TYR B 2 63  ? 96.023  102.292 123.851 1.00 93.96  ? 63  TYR H N   1 
ATOM 1265 C CA  . TYR B 2 63  ? 95.631  102.368 125.248 1.00 93.96  ? 63  TYR H CA  1 
ATOM 1266 C C   . TYR B 2 63  ? 96.815  102.030 126.142 1.00 93.96  ? 63  TYR H C   1 
ATOM 1267 O O   . TYR B 2 63  ? 97.669  101.211 125.788 1.00 93.96  ? 63  TYR H O   1 
ATOM 1268 C CB  . TYR B 2 63  ? 94.470  101.414 125.570 1.00 93.96  ? 63  TYR H CB  1 
ATOM 1269 C CG  . TYR B 2 63  ? 93.151  101.765 124.916 1.00 93.96  ? 63  TYR H CG  1 
ATOM 1270 C CD1 . TYR B 2 63  ? 92.033  102.053 125.685 1.00 93.96  ? 63  TYR H CD1 1 
ATOM 1271 C CD2 . TYR B 2 63  ? 93.016  101.785 123.535 1.00 93.96  ? 63  TYR H CD2 1 
ATOM 1272 C CE1 . TYR B 2 63  ? 90.825  102.368 125.099 1.00 93.96  ? 63  TYR H CE1 1 
ATOM 1273 C CE2 . TYR B 2 63  ? 91.811  102.100 122.940 1.00 93.96  ? 63  TYR H CE2 1 
ATOM 1274 C CZ  . TYR B 2 63  ? 90.719  102.389 123.726 1.00 93.96  ? 63  TYR H CZ  1 
ATOM 1275 O OH  . TYR B 2 63  ? 89.517  102.702 123.136 1.00 93.96  ? 63  TYR H OH  1 
ATOM 1276 N N   . ASN B 2 64  ? 96.859  102.674 127.303 1.00 94.93  ? 64  ASN H N   1 
ATOM 1277 C CA  . ASN B 2 64  ? 97.838  102.318 128.317 1.00 94.93  ? 64  ASN H CA  1 
ATOM 1278 C C   . ASN B 2 64  ? 97.555  100.913 128.834 1.00 94.93  ? 64  ASN H C   1 
ATOM 1279 O O   . ASN B 2 64  ? 96.426  100.421 128.771 1.00 94.93  ? 64  ASN H O   1 
ATOM 1280 C CB  . ASN B 2 64  ? 97.810  103.326 129.466 1.00 94.93  ? 64  ASN H CB  1 
ATOM 1281 C CG  . ASN B 2 64  ? 98.857  103.040 130.524 1.00 94.93  ? 64  ASN H CG  1 
ATOM 1282 O OD1 . ASN B 2 64  ? 100.006 103.467 130.408 1.00 94.93  ? 64  ASN H OD1 1 
ATOM 1283 N ND2 . ASN B 2 64  ? 98.463  102.319 131.566 1.00 94.93  ? 64  ASN H ND2 1 
ATOM 1284 N N   . GLN B 2 65  ? 98.602  100.260 129.334 1.00 108.19 ? 65  GLN H N   1 
ATOM 1285 C CA  . GLN B 2 65  ? 98.466  98.904  129.843 1.00 108.19 ? 65  GLN H CA  1 
ATOM 1286 C C   . GLN B 2 65  ? 97.426  98.848  130.959 1.00 108.19 ? 65  GLN H C   1 
ATOM 1287 O O   . GLN B 2 65  ? 97.121  99.854  131.604 1.00 108.19 ? 65  GLN H O   1 
ATOM 1288 C CB  . GLN B 2 65  ? 99.818  98.393  130.348 1.00 108.19 ? 65  GLN H CB  1 
ATOM 1289 C CG  . GLN B 2 65  ? 99.902  96.884  130.522 1.00 108.19 ? 65  GLN H CG  1 
ATOM 1290 C CD  . GLN B 2 65  ? 99.164  96.129  129.434 1.00 108.19 ? 65  GLN H CD  1 
ATOM 1291 O OE1 . GLN B 2 65  ? 98.029  95.693  129.627 1.00 108.19 ? 65  GLN H OE1 1 
ATOM 1292 N NE2 . GLN B 2 65  ? 99.805  95.971  128.283 1.00 108.19 ? 65  GLN H NE2 1 
ATOM 1293 N N   . LYS B 2 66  ? 96.859  97.653  131.151 1.00 109.59 ? 66  LYS H N   1 
ATOM 1294 C CA  . LYS B 2 66  ? 95.840  97.339  132.165 1.00 109.59 ? 66  LYS H CA  1 
ATOM 1295 C C   . LYS B 2 66  ? 94.700  98.360  132.206 1.00 109.59 ? 66  LYS H C   1 
ATOM 1296 O O   . LYS B 2 66  ? 94.019  98.493  133.227 1.00 109.59 ? 66  LYS H O   1 
ATOM 1297 C CB  . LYS B 2 66  ? 96.455  97.152  133.565 1.00 109.59 ? 66  LYS H CB  1 
ATOM 1298 C CG  . LYS B 2 66  ? 97.288  98.299  134.135 1.00 109.59 ? 66  LYS H CG  1 
ATOM 1299 C CD  . LYS B 2 66  ? 96.486  99.183  135.075 1.00 109.59 ? 66  LYS H CD  1 
ATOM 1300 C CE  . LYS B 2 66  ? 97.354  100.282 135.666 1.00 109.59 ? 66  LYS H CE  1 
ATOM 1301 N NZ  . LYS B 2 66  ? 96.595  101.147 136.609 1.00 109.59 ? 66  LYS H NZ  1 
ATOM 1302 N N   . PHE B 2 67  ? 94.453  99.062  131.098 1.00 109.47 ? 67  PHE H N   1 
ATOM 1303 C CA  . PHE B 2 67  ? 93.312  99.961  130.976 1.00 109.47 ? 67  PHE H CA  1 
ATOM 1304 C C   . PHE B 2 67  ? 92.400  99.633  129.803 1.00 109.47 ? 67  PHE H C   1 
ATOM 1305 O O   . PHE B 2 67  ? 91.433  100.367 129.573 1.00 109.47 ? 67  PHE H O   1 
ATOM 1306 C CB  . PHE B 2 67  ? 93.775  101.421 130.855 1.00 109.47 ? 67  PHE H CB  1 
ATOM 1307 C CG  . PHE B 2 67  ? 94.180  102.047 132.160 1.00 109.47 ? 67  PHE H CG  1 
ATOM 1308 C CD1 . PHE B 2 67  ? 93.823  101.468 133.364 1.00 109.47 ? 67  PHE H CD1 1 
ATOM 1309 C CD2 . PHE B 2 67  ? 94.904  103.226 132.181 1.00 109.47 ? 67  PHE H CD2 1 
ATOM 1310 C CE1 . PHE B 2 67  ? 94.189  102.046 134.563 1.00 109.47 ? 67  PHE H CE1 1 
ATOM 1311 C CE2 . PHE B 2 67  ? 95.273  103.808 133.378 1.00 109.47 ? 67  PHE H CE2 1 
ATOM 1312 C CZ  . PHE B 2 67  ? 94.915  103.217 134.570 1.00 109.47 ? 67  PHE H CZ  1 
ATOM 1313 N N   . MET B 2 68  ? 92.672  98.562  129.054 1.00 118.45 ? 68  MET H N   1 
ATOM 1314 C CA  . MET B 2 68  ? 91.803  98.214  127.934 1.00 118.45 ? 68  MET H CA  1 
ATOM 1315 C C   . MET B 2 68  ? 90.418  97.791  128.405 1.00 118.45 ? 68  MET H C   1 
ATOM 1316 O O   . MET B 2 68  ? 89.433  97.988  127.685 1.00 118.45 ? 68  MET H O   1 
ATOM 1317 C CB  . MET B 2 68  ? 92.436  97.104  127.094 1.00 118.45 ? 68  MET H CB  1 
ATOM 1318 C CG  . MET B 2 68  ? 93.559  97.572  126.183 1.00 118.45 ? 68  MET H CG  1 
ATOM 1319 S SD  . MET B 2 68  ? 95.073  97.960  127.077 1.00 118.45 ? 68  MET H SD  1 
ATOM 1320 C CE  . MET B 2 68  ? 95.655  96.315  127.477 1.00 118.45 ? 68  MET H CE  1 
ATOM 1321 N N   . GLY B 2 69  ? 90.323  97.205  129.599 1.00 120.87 ? 69  GLY H N   1 
ATOM 1322 C CA  . GLY B 2 69  ? 89.028  96.775  130.101 1.00 120.87 ? 69  GLY H CA  1 
ATOM 1323 C C   . GLY B 2 69  ? 88.101  97.929  130.435 1.00 120.87 ? 69  GLY H C   1 
ATOM 1324 O O   . GLY B 2 69  ? 86.889  97.844  130.217 1.00 120.87 ? 69  GLY H O   1 
ATOM 1325 N N   . LYS B 2 70  ? 88.651  99.021  130.967 1.00 120.72 ? 70  LYS H N   1 
ATOM 1326 C CA  . LYS B 2 70  ? 87.851  100.117 131.502 1.00 120.72 ? 70  LYS H CA  1 
ATOM 1327 C C   . LYS B 2 70  ? 88.052  101.415 130.727 1.00 120.72 ? 70  LYS H C   1 
ATOM 1328 O O   . LYS B 2 70  ? 88.015  102.501 131.310 1.00 120.72 ? 70  LYS H O   1 
ATOM 1329 C CB  . LYS B 2 70  ? 88.164  100.335 132.982 1.00 120.72 ? 70  LYS H CB  1 
ATOM 1330 C CG  . LYS B 2 70  ? 88.219  99.060  133.804 1.00 120.72 ? 70  LYS H CG  1 
ATOM 1331 C CD  . LYS B 2 70  ? 89.144  99.217  135.001 1.00 120.72 ? 70  LYS H CD  1 
ATOM 1332 C CE  . LYS B 2 70  ? 88.810  100.466 135.800 1.00 120.72 ? 70  LYS H CE  1 
ATOM 1333 N NZ  . LYS B 2 70  ? 89.593  100.542 137.064 1.00 120.72 ? 70  LYS H NZ  1 
ATOM 1334 N N   . ALA B 2 71  ? 88.265  101.329 129.416 1.00 113.35 ? 71  ALA H N   1 
ATOM 1335 C CA  . ALA B 2 71  ? 88.430  102.531 128.613 1.00 113.35 ? 71  ALA H CA  1 
ATOM 1336 C C   . ALA B 2 71  ? 87.934  102.279 127.198 1.00 113.35 ? 71  ALA H C   1 
ATOM 1337 O O   . ALA B 2 71  ? 88.017  101.160 126.682 1.00 113.35 ? 71  ALA H O   1 
ATOM 1338 C CB  . ALA B 2 71  ? 89.890  102.997 128.585 1.00 113.35 ? 71  ALA H CB  1 
ATOM 1339 N N   . THR B 2 72  ? 87.417  103.338 126.577 1.00 111.46 ? 72  THR H N   1 
ATOM 1340 C CA  . THR B 2 72  ? 86.965  103.285 125.188 1.00 111.46 ? 72  THR H CA  1 
ATOM 1341 C C   . THR B 2 72  ? 86.943  104.714 124.665 1.00 111.46 ? 72  THR H C   1 
ATOM 1342 O O   . THR B 2 72  ? 86.172  105.539 125.163 1.00 111.46 ? 72  THR H O   1 
ATOM 1343 C CB  . THR B 2 72  ? 85.588  102.639 125.078 1.00 111.46 ? 72  THR H CB  1 
ATOM 1344 O OG1 . THR B 2 72  ? 85.651  101.284 125.542 1.00 111.46 ? 72  THR H OG1 1 
ATOM 1345 C CG2 . THR B 2 72  ? 85.110  102.653 123.634 1.00 111.46 ? 72  THR H CG2 1 
ATOM 1346 N N   . LEU B 2 73  ? 87.778  105.003 123.672 1.00 101.15 ? 73  LEU H N   1 
ATOM 1347 C CA  . LEU B 2 73  ? 87.932  106.351 123.137 1.00 101.15 ? 73  LEU H CA  1 
ATOM 1348 C C   . LEU B 2 73  ? 87.289  106.426 121.759 1.00 101.15 ? 73  LEU H C   1 
ATOM 1349 O O   . LEU B 2 73  ? 87.683  105.695 120.844 1.00 101.15 ? 73  LEU H O   1 
ATOM 1350 C CB  . LEU B 2 73  ? 89.406  106.750 123.062 1.00 101.15 ? 73  LEU H CB  1 
ATOM 1351 C CG  . LEU B 2 73  ? 90.114  107.172 124.353 1.00 101.15 ? 73  LEU H CG  1 
ATOM 1352 C CD1 . LEU B 2 73  ? 90.356  105.993 125.284 1.00 101.15 ? 73  LEU H CD1 1 
ATOM 1353 C CD2 . LEU B 2 73  ? 91.423  107.871 124.028 1.00 101.15 ? 73  LEU H CD2 1 
ATOM 1354 N N   . THR B 2 74  ? 86.304  107.311 121.616 1.00 107.20 ? 74  THR H N   1 
ATOM 1355 C CA  . THR B 2 74  ? 85.648  107.572 120.343 1.00 107.20 ? 74  THR H CA  1 
ATOM 1356 C C   . THR B 2 74  ? 85.626  109.073 120.098 1.00 107.20 ? 74  THR H C   1 
ATOM 1357 O O   . THR B 2 74  ? 85.559  109.870 121.038 1.00 107.20 ? 74  THR H O   1 
ATOM 1358 C CB  . THR B 2 74  ? 84.212  107.024 120.306 1.00 107.20 ? 74  THR H CB  1 
ATOM 1359 O OG1 . THR B 2 74  ? 83.350  107.885 121.060 1.00 107.20 ? 74  THR H OG1 1 
ATOM 1360 C CG2 . THR B 2 74  ? 84.150  105.617 120.885 1.00 107.20 ? 74  THR H CG2 1 
ATOM 1361 N N   . VAL B 2 75  ? 85.687  109.456 118.825 1.00 106.90 ? 75  VAL H N   1 
ATOM 1362 C CA  . VAL B 2 75  ? 85.767  110.857 118.430 1.00 106.90 ? 75  VAL H CA  1 
ATOM 1363 C C   . VAL B 2 75  ? 84.776  111.110 117.304 1.00 106.90 ? 75  VAL H C   1 
ATOM 1364 O O   . VAL B 2 75  ? 84.699  110.326 116.352 1.00 106.90 ? 75  VAL H O   1 
ATOM 1365 C CB  . VAL B 2 75  ? 87.192  111.245 117.991 1.00 106.90 ? 75  VAL H CB  1 
ATOM 1366 C CG1 . VAL B 2 75  ? 87.215  112.658 117.433 1.00 106.90 ? 75  VAL H CG1 1 
ATOM 1367 C CG2 . VAL B 2 75  ? 88.158  111.120 119.157 1.00 106.90 ? 75  VAL H CG2 1 
ATOM 1368 N N   . ASP B 2 76  ? 84.022  112.201 117.414 1.00 114.71 ? 76  ASP H N   1 
ATOM 1369 C CA  . ASP B 2 76  ? 83.134  112.660 116.355 1.00 114.71 ? 76  ASP H CA  1 
ATOM 1370 C C   . ASP B 2 76  ? 83.827  113.792 115.607 1.00 114.71 ? 76  ASP H C   1 
ATOM 1371 O O   . ASP B 2 76  ? 84.066  114.862 116.177 1.00 114.71 ? 76  ASP H O   1 
ATOM 1372 C CB  . ASP B 2 76  ? 81.795  113.125 116.927 1.00 114.71 ? 76  ASP H CB  1 
ATOM 1373 C CG  . ASP B 2 76  ? 80.872  113.698 115.867 1.00 114.71 ? 76  ASP H CG  1 
ATOM 1374 O OD1 . ASP B 2 76  ? 81.022  113.336 114.681 1.00 114.71 ? 76  ASP H OD1 1 
ATOM 1375 O OD2 . ASP B 2 76  ? 79.995  114.514 116.221 1.00 114.71 ? 76  ASP H OD2 1 
ATOM 1376 N N   . ARG B 2 77  ? 84.146  113.556 114.334 1.00 110.45 ? 77  ARG H N   1 
ATOM 1377 C CA  . ARG B 2 77  ? 84.906  114.525 113.555 1.00 110.45 ? 77  ARG H CA  1 
ATOM 1378 C C   . ARG B 2 77  ? 84.079  115.731 113.130 1.00 110.45 ? 77  ARG H C   1 
ATOM 1379 O O   . ARG B 2 77  ? 84.638  116.822 112.975 1.00 110.45 ? 77  ARG H O   1 
ATOM 1380 C CB  . ARG B 2 77  ? 85.499  113.851 112.315 1.00 110.45 ? 77  ARG H CB  1 
ATOM 1381 C CG  . ARG B 2 77  ? 86.706  112.975 112.606 1.00 110.45 ? 77  ARG H CG  1 
ATOM 1382 C CD  . ARG B 2 77  ? 87.889  113.804 113.077 1.00 110.45 ? 77  ARG H CD  1 
ATOM 1383 N NE  . ARG B 2 77  ? 88.751  114.221 111.977 1.00 110.45 ? 77  ARG H NE  1 
ATOM 1384 C CZ  . ARG B 2 77  ? 89.568  113.414 111.313 1.00 110.45 ? 77  ARG H CZ  1 
ATOM 1385 N NH1 . ARG B 2 77  ? 89.672  112.131 111.618 1.00 110.45 ? 77  ARG H NH1 1 
ATOM 1386 N NH2 . ARG B 2 77  ? 90.303  113.908 110.321 1.00 110.45 ? 77  ARG H NH2 1 
ATOM 1387 N N   . SER B 2 78  ? 82.770  115.562 112.934 1.00 115.34 ? 78  SER H N   1 
ATOM 1388 C CA  . SER B 2 78  ? 81.941  116.668 112.464 1.00 115.34 ? 78  SER H CA  1 
ATOM 1389 C C   . SER B 2 78  ? 81.849  117.774 113.508 1.00 115.34 ? 78  SER H C   1 
ATOM 1390 O O   . SER B 2 78  ? 82.006  118.958 113.188 1.00 115.34 ? 78  SER H O   1 
ATOM 1391 C CB  . SER B 2 78  ? 80.549  116.158 112.095 1.00 115.34 ? 78  SER H CB  1 
ATOM 1392 O OG  . SER B 2 78  ? 79.792  115.859 113.255 1.00 115.34 ? 78  SER H OG  1 
ATOM 1393 N N   . SER B 2 79  ? 81.595  117.409 114.761 1.00 115.42 ? 79  SER H N   1 
ATOM 1394 C CA  . SER B 2 79  ? 81.439  118.379 115.836 1.00 115.42 ? 79  SER H CA  1 
ATOM 1395 C C   . SER B 2 79  ? 82.744  118.685 116.558 1.00 115.42 ? 79  SER H C   1 
ATOM 1396 O O   . SER B 2 79  ? 82.746  119.518 117.471 1.00 115.42 ? 79  SER H O   1 
ATOM 1397 C CB  . SER B 2 79  ? 80.398  117.884 116.845 1.00 115.42 ? 79  SER H CB  1 
ATOM 1398 O OG  . SER B 2 79  ? 80.824  116.684 117.467 1.00 115.42 ? 79  SER H OG  1 
ATOM 1399 N N   . SER B 2 80  ? 83.846  118.037 116.171 1.00 110.76 ? 80  SER H N   1 
ATOM 1400 C CA  . SER B 2 80  ? 85.150  118.231 116.808 1.00 110.76 ? 80  SER H CA  1 
ATOM 1401 C C   . SER B 2 80  ? 85.074  117.987 118.313 1.00 110.76 ? 80  SER H C   1 
ATOM 1402 O O   . SER B 2 80  ? 85.683  118.703 119.110 1.00 110.76 ? 80  SER H O   1 
ATOM 1403 C CB  . SER B 2 80  ? 85.711  119.623 116.509 1.00 110.76 ? 80  SER H CB  1 
ATOM 1404 O OG  . SER B 2 80  ? 85.161  120.591 117.385 1.00 110.76 ? 80  SER H OG  1 
ATOM 1405 N N   . THR B 2 81  ? 84.316  116.966 118.705 1.00 113.75 ? 81  THR H N   1 
ATOM 1406 C CA  . THR B 2 81  ? 84.132  116.607 120.103 1.00 113.75 ? 81  THR H CA  1 
ATOM 1407 C C   . THR B 2 81  ? 84.625  115.186 120.324 1.00 113.75 ? 81  THR H C   1 
ATOM 1408 O O   . THR B 2 81  ? 84.252  114.272 119.580 1.00 113.75 ? 81  THR H O   1 
ATOM 1409 C CB  . THR B 2 81  ? 82.661  116.728 120.515 1.00 113.75 ? 81  THR H CB  1 
ATOM 1410 O OG1 . THR B 2 81  ? 82.221  118.080 120.329 1.00 113.75 ? 81  THR H OG1 1 
ATOM 1411 C CG2 . THR B 2 81  ? 82.480  116.339 121.974 1.00 113.75 ? 81  THR H CG2 1 
ATOM 1412 N N   . ALA B 2 82  ? 85.461  115.002 121.343 1.00 108.74 ? 82  ALA H N   1 
ATOM 1413 C CA  . ALA B 2 82  ? 86.008  113.698 121.695 1.00 108.74 ? 82  ALA H CA  1 
ATOM 1414 C C   . ALA B 2 82  ? 85.492  113.310 123.071 1.00 108.74 ? 82  ALA H C   1 
ATOM 1415 O O   . ALA B 2 82  ? 85.662  114.063 124.036 1.00 108.74 ? 82  ALA H O   1 
ATOM 1416 C CB  . ALA B 2 82  ? 87.537  113.717 121.678 1.00 108.74 ? 82  ALA H CB  1 
ATOM 1417 N N   . TYR B 2 83  ? 84.869  112.138 123.161 1.00 112.47 ? 83  TYR H N   1 
ATOM 1418 C CA  . TYR B 2 83  ? 84.299  111.646 124.406 1.00 112.47 ? 83  TYR H CA  1 
ATOM 1419 C C   . TYR B 2 83  ? 84.698  110.193 124.622 1.00 112.47 ? 83  TYR H C   1 
ATOM 1420 O O   . TYR B 2 83  ? 84.740  109.402 123.675 1.00 112.47 ? 83  TYR H O   1 
ATOM 1421 C CB  . TYR B 2 83  ? 82.769  111.801 124.413 1.00 112.47 ? 83  TYR H CB  1 
ATOM 1422 C CG  . TYR B 2 83  ? 82.041  110.998 123.357 1.00 112.47 ? 83  TYR H CG  1 
ATOM 1423 C CD1 . TYR B 2 83  ? 81.795  111.535 122.101 1.00 112.47 ? 83  TYR H CD1 1 
ATOM 1424 C CD2 . TYR B 2 83  ? 81.583  109.715 123.622 1.00 112.47 ? 83  TYR H CD2 1 
ATOM 1425 C CE1 . TYR B 2 83  ? 81.126  110.812 121.133 1.00 112.47 ? 83  TYR H CE1 1 
ATOM 1426 C CE2 . TYR B 2 83  ? 80.911  108.984 122.660 1.00 112.47 ? 83  TYR H CE2 1 
ATOM 1427 C CZ  . TYR B 2 83  ? 80.686  109.538 121.417 1.00 112.47 ? 83  TYR H CZ  1 
ATOM 1428 O OH  . TYR B 2 83  ? 80.019  108.814 120.456 1.00 112.47 ? 83  TYR H OH  1 
ATOM 1429 N N   . MET B 2 84  ? 84.989  109.851 125.874 1.00 115.25 ? 84  MET H N   1 
ATOM 1430 C CA  . MET B 2 84  ? 85.470  108.530 126.245 1.00 115.25 ? 84  MET H CA  1 
ATOM 1431 C C   . MET B 2 84  ? 84.543  107.907 127.281 1.00 115.25 ? 84  MET H C   1 
ATOM 1432 O O   . MET B 2 84  ? 83.872  108.611 128.041 1.00 115.25 ? 84  MET H O   1 
ATOM 1433 C CB  . MET B 2 84  ? 86.908  108.602 126.780 1.00 115.25 ? 84  MET H CB  1 
ATOM 1434 C CG  . MET B 2 84  ? 87.076  109.452 128.028 1.00 115.25 ? 84  MET H CG  1 
ATOM 1435 S SD  . MET B 2 84  ? 87.026  108.498 129.553 1.00 115.25 ? 84  MET H SD  1 
ATOM 1436 C CE  . MET B 2 84  ? 88.366  107.345 129.270 1.00 115.25 ? 84  MET H CE  1 
ATOM 1437 N N   . ASP B 2 85  ? 84.513  106.577 127.302 1.00 122.80 ? 85  ASP H N   1 
ATOM 1438 C CA  . ASP B 2 85  ? 83.550  105.820 128.086 1.00 122.80 ? 85  ASP H CA  1 
ATOM 1439 C C   . ASP B 2 85  ? 84.235  105.037 129.199 1.00 122.80 ? 85  ASP H C   1 
ATOM 1440 O O   . ASP B 2 85  ? 85.418  104.697 129.118 1.00 122.80 ? 85  ASP H O   1 
ATOM 1441 C CB  . ASP B 2 85  ? 82.764  104.852 127.194 1.00 122.80 ? 85  ASP H CB  1 
ATOM 1442 C CG  . ASP B 2 85  ? 81.922  105.566 126.159 1.00 122.80 ? 85  ASP H CG  1 
ATOM 1443 O OD1 . ASP B 2 85  ? 81.528  106.722 126.411 1.00 122.80 ? 85  ASP H OD1 1 
ATOM 1444 O OD2 . ASP B 2 85  ? 81.654  104.972 125.094 1.00 122.80 ? 85  ASP H OD2 1 
ATOM 1445 N N   . LEU B 2 86  ? 83.464  104.755 130.246 1.00 131.19 ? 86  LEU H N   1 
ATOM 1446 C CA  . LEU B 2 86  ? 83.867  103.863 131.324 1.00 131.19 ? 86  LEU H CA  1 
ATOM 1447 C C   . LEU B 2 86  ? 82.815  102.774 131.483 1.00 131.19 ? 86  LEU H C   1 
ATOM 1448 O O   . LEU B 2 86  ? 81.619  103.025 131.307 1.00 131.19 ? 86  LEU H O   1 
ATOM 1449 C CB  . LEU B 2 86  ? 84.043  104.612 132.652 1.00 131.19 ? 86  LEU H CB  1 
ATOM 1450 C CG  . LEU B 2 86  ? 85.356  105.359 132.897 1.00 131.19 ? 86  LEU H CG  1 
ATOM 1451 C CD1 . LEU B 2 86  ? 85.421  106.632 132.078 1.00 131.19 ? 86  LEU H CD1 1 
ATOM 1452 C CD2 . LEU B 2 86  ? 85.530  105.664 134.376 1.00 131.19 ? 86  LEU H CD2 1 
ATOM 1453 N N   . HIS B 2 87  ? 83.264  101.565 131.814 1.00 134.51 ? 87  HIS H N   1 
ATOM 1454 C CA  . HIS B 2 87  ? 82.375  100.414 131.923 1.00 134.51 ? 87  HIS H CA  1 
ATOM 1455 C C   . HIS B 2 87  ? 82.106  100.008 133.367 1.00 134.51 ? 87  HIS H C   1 
ATOM 1456 O O   . HIS B 2 87  ? 80.945  99.900  133.773 1.00 134.51 ? 87  HIS H O   1 
ATOM 1457 C CB  . HIS B 2 87  ? 82.957  99.230  131.144 1.00 134.51 ? 87  HIS H CB  1 
ATOM 1458 C CG  . HIS B 2 87  ? 83.061  99.472  129.671 1.00 134.51 ? 87  HIS H CG  1 
ATOM 1459 N ND1 . HIS B 2 87  ? 82.577  100.613 129.068 1.00 134.51 ? 87  HIS H ND1 1 
ATOM 1460 C CD2 . HIS B 2 87  ? 83.595  98.721  128.679 1.00 134.51 ? 87  HIS H CD2 1 
ATOM 1461 C CE1 . HIS B 2 87  ? 82.808  100.555 127.769 1.00 134.51 ? 87  HIS H CE1 1 
ATOM 1462 N NE2 . HIS B 2 87  ? 83.424  99.417  127.506 1.00 134.51 ? 87  HIS H NE2 1 
ATOM 1463 N N   . ASN B 2 88  ? 83.153  99.781  134.154 1.00 139.36 ? 88  ASN H N   1 
ATOM 1464 C CA  . ASN B 2 88  ? 83.016  99.374  135.543 1.00 139.36 ? 88  ASN H CA  1 
ATOM 1465 C C   . ASN B 2 88  ? 83.504  100.490 136.457 1.00 139.36 ? 88  ASN H C   1 
ATOM 1466 O O   . ASN B 2 88  ? 84.440  101.222 136.124 1.00 139.36 ? 88  ASN H O   1 
ATOM 1467 C CB  . ASN B 2 88  ? 83.793  98.084  135.827 1.00 139.36 ? 88  ASN H CB  1 
ATOM 1468 C CG  . ASN B 2 88  ? 82.953  96.840  135.613 1.00 139.36 ? 88  ASN H CG  1 
ATOM 1469 O OD1 . ASN B 2 88  ? 81.748  96.925  135.376 1.00 139.36 ? 88  ASN H OD1 1 
ATOM 1470 N ND2 . ASN B 2 88  ? 83.587  95.676  135.695 1.00 139.36 ? 88  ASN H ND2 1 
ATOM 1471 N N   . LEU B 2 89  ? 82.856  100.614 137.617 1.00 135.86 ? 89  LEU H N   1 
ATOM 1472 C CA  . LEU B 2 89  ? 83.123  101.711 138.553 1.00 135.86 ? 89  LEU H CA  1 
ATOM 1473 C C   . LEU B 2 89  ? 83.259  101.129 139.959 1.00 135.86 ? 89  LEU H C   1 
ATOM 1474 O O   . LEU B 2 89  ? 82.271  100.990 140.684 1.00 135.86 ? 89  LEU H O   1 
ATOM 1475 C CB  . LEU B 2 89  ? 82.023  102.762 138.486 1.00 135.86 ? 89  LEU H CB  1 
ATOM 1476 C CG  . LEU B 2 89  ? 81.745  103.381 137.117 1.00 135.86 ? 89  LEU H CG  1 
ATOM 1477 C CD1 . LEU B 2 89  ? 80.411  104.105 137.126 1.00 135.86 ? 89  LEU H CD1 1 
ATOM 1478 C CD2 . LEU B 2 89  ? 82.869  104.322 136.716 1.00 135.86 ? 89  LEU H CD2 1 
ATOM 1479 N N   . THR B 2 90  ? 84.492  100.794 140.337 1.00 129.99 ? 90  THR H N   1 
ATOM 1480 C CA  . THR B 2 90  ? 84.806  100.358 141.691 1.00 129.99 ? 90  THR H CA  1 
ATOM 1481 C C   . THR B 2 90  ? 85.726  101.348 142.394 1.00 129.99 ? 90  THR H C   1 
ATOM 1482 O O   . THR B 2 90  ? 85.400  101.843 143.476 1.00 129.99 ? 90  THR H O   1 
ATOM 1483 C CB  . THR B 2 90  ? 85.442  98.962  141.668 1.00 129.99 ? 90  THR H CB  1 
ATOM 1484 O OG1 . THR B 2 90  ? 86.698  99.019  140.979 1.00 129.99 ? 90  THR H OG1 1 
ATOM 1485 C CG2 . THR B 2 90  ? 84.527  97.971  140.964 1.00 129.99 ? 90  THR H CG2 1 
ATOM 1486 N N   . SER B 2 91  ? 86.878  101.652 141.795 1.00 126.14 ? 91  SER H N   1 
ATOM 1487 C CA  . SER B 2 91  ? 87.774  102.678 142.302 1.00 126.14 ? 91  SER H CA  1 
ATOM 1488 C C   . SER B 2 91  ? 88.221  103.654 141.223 1.00 126.14 ? 91  SER H C   1 
ATOM 1489 O O   . SER B 2 91  ? 88.887  104.644 141.547 1.00 126.14 ? 91  SER H O   1 
ATOM 1490 C CB  . SER B 2 91  ? 89.010  102.042 142.957 1.00 126.14 ? 91  SER H CB  1 
ATOM 1491 O OG  . SER B 2 91  ? 88.651  101.310 144.115 1.00 126.14 ? 91  SER H OG  1 
ATOM 1492 N N   . ALA B 2 92  ? 87.888  103.400 139.955 1.00 120.65 ? 92  ALA H N   1 
ATOM 1493 C CA  . ALA B 2 92  ? 88.225  104.344 138.895 1.00 120.65 ? 92  ALA H CA  1 
ATOM 1494 C C   . ALA B 2 92  ? 87.481  105.661 139.072 1.00 120.65 ? 92  ALA H C   1 
ATOM 1495 O O   . ALA B 2 92  ? 88.057  106.737 138.876 1.00 120.65 ? 92  ALA H O   1 
ATOM 1496 C CB  . ALA B 2 92  ? 87.918  103.730 137.530 1.00 120.65 ? 92  ALA H CB  1 
ATOM 1497 N N   . ASP B 2 93  ? 86.201  105.598 139.444 1.00 126.96 ? 93  ASP H N   1 
ATOM 1498 C CA  . ASP B 2 93  ? 85.396  106.797 139.674 1.00 126.96 ? 93  ASP H CA  1 
ATOM 1499 C C   . ASP B 2 93  ? 85.767  107.394 141.033 1.00 126.96 ? 93  ASP H C   1 
ATOM 1500 O O   . ASP B 2 93  ? 84.999  107.381 141.997 1.00 126.96 ? 93  ASP H O   1 
ATOM 1501 C CB  . ASP B 2 93  ? 83.911  106.471 139.593 1.00 126.96 ? 93  ASP H CB  1 
ATOM 1502 C CG  . ASP B 2 93  ? 83.537  105.244 140.403 1.00 126.96 ? 93  ASP H CG  1 
ATOM 1503 O OD1 . ASP B 2 93  ? 84.437  104.435 140.711 1.00 126.96 ? 93  ASP H OD1 1 
ATOM 1504 O OD2 . ASP B 2 93  ? 82.343  105.094 140.739 1.00 126.96 ? 93  ASP H OD2 1 
ATOM 1505 N N   . SER B 2 94  ? 86.983  107.934 141.093 1.00 116.04 ? 94  SER H N   1 
ATOM 1506 C CA  . SER B 2 94  ? 87.537  108.451 142.336 1.00 116.04 ? 94  SER H CA  1 
ATOM 1507 C C   . SER B 2 94  ? 87.700  109.965 142.316 1.00 116.04 ? 94  SER H C   1 
ATOM 1508 O O   . SER B 2 94  ? 87.165  110.653 143.189 1.00 116.04 ? 94  SER H O   1 
ATOM 1509 C CB  . SER B 2 94  ? 88.882  107.774 142.629 1.00 116.04 ? 94  SER H CB  1 
ATOM 1510 O OG  . SER B 2 94  ? 88.709  106.393 142.892 1.00 116.04 ? 94  SER H OG  1 
ATOM 1511 N N   . ALA B 2 95  ? 88.423  110.508 141.344 1.00 105.33 ? 95  ALA H N   1 
ATOM 1512 C CA  . ALA B 2 95  ? 88.748  111.928 141.373 1.00 105.33 ? 95  ALA H CA  1 
ATOM 1513 C C   . ALA B 2 95  ? 88.891  112.437 139.941 1.00 105.33 ? 95  ALA H C   1 
ATOM 1514 O O   . ALA B 2 95  ? 88.443  111.790 138.989 1.00 105.33 ? 95  ALA H O   1 
ATOM 1515 C CB  . ALA B 2 95  ? 90.002  112.167 142.230 1.00 105.33 ? 95  ALA H CB  1 
ATOM 1516 N N   . VAL B 2 96  ? 89.521  113.605 139.798 1.00 95.09  ? 96  VAL H N   1 
ATOM 1517 C CA  . VAL B 2 96  ? 89.456  114.383 138.566 1.00 95.09  ? 96  VAL H CA  1 
ATOM 1518 C C   . VAL B 2 96  ? 90.148  113.662 137.412 1.00 95.09  ? 96  VAL H C   1 
ATOM 1519 O O   . VAL B 2 96  ? 91.164  112.975 137.586 1.00 95.09  ? 96  VAL H O   1 
ATOM 1520 C CB  . VAL B 2 96  ? 90.067  115.776 138.806 1.00 95.09  ? 96  VAL H CB  1 
ATOM 1521 C CG1 . VAL B 2 96  ? 91.552  115.668 139.121 1.00 95.09  ? 96  VAL H CG1 1 
ATOM 1522 C CG2 . VAL B 2 96  ? 89.839  116.681 137.611 1.00 95.09  ? 96  VAL H CG2 1 
ATOM 1523 N N   . TYR B 2 97  ? 89.573  113.810 136.218 1.00 90.24  ? 97  TYR H N   1 
ATOM 1524 C CA  . TYR B 2 97  ? 90.167  113.363 134.964 1.00 90.24  ? 97  TYR H CA  1 
ATOM 1525 C C   . TYR B 2 97  ? 90.477  114.588 134.116 1.00 90.24  ? 97  TYR H C   1 
ATOM 1526 O O   . TYR B 2 97  ? 89.690  115.539 134.088 1.00 90.24  ? 97  TYR H O   1 
ATOM 1527 C CB  . TYR B 2 97  ? 89.233  112.424 134.188 1.00 90.24  ? 97  TYR H CB  1 
ATOM 1528 C CG  . TYR B 2 97  ? 88.956  111.074 134.823 1.00 90.24  ? 97  TYR H CG  1 
ATOM 1529 C CD1 . TYR B 2 97  ? 89.342  110.791 136.125 1.00 90.24  ? 97  TYR H CD1 1 
ATOM 1530 C CD2 . TYR B 2 97  ? 88.301  110.081 134.108 1.00 90.24  ? 97  TYR H CD2 1 
ATOM 1531 C CE1 . TYR B 2 97  ? 89.085  109.560 136.696 1.00 90.24  ? 97  TYR H CE1 1 
ATOM 1532 C CE2 . TYR B 2 97  ? 88.040  108.847 134.670 1.00 90.24  ? 97  TYR H CE2 1 
ATOM 1533 C CZ  . TYR B 2 97  ? 88.435  108.593 135.964 1.00 90.24  ? 97  TYR H CZ  1 
ATOM 1534 O OH  . TYR B 2 97  ? 88.177  107.365 136.529 1.00 90.24  ? 97  TYR H OH  1 
ATOM 1535 N N   . PHE B 2 98  ? 91.613  114.567 133.428 1.00 79.87  ? 98  PHE H N   1 
ATOM 1536 C CA  . PHE B 2 98  ? 92.047  115.686 132.603 1.00 79.87  ? 98  PHE H CA  1 
ATOM 1537 C C   . PHE B 2 98  ? 91.945  115.338 131.123 1.00 79.87  ? 98  PHE H C   1 
ATOM 1538 O O   . PHE B 2 98  ? 91.804  114.176 130.734 1.00 79.87  ? 98  PHE H O   1 
ATOM 1539 C CB  . PHE B 2 98  ? 93.481  116.099 132.952 1.00 79.87  ? 98  PHE H CB  1 
ATOM 1540 C CG  . PHE B 2 98  ? 93.585  116.933 134.194 1.00 79.87  ? 98  PHE H CG  1 
ATOM 1541 C CD1 . PHE B 2 98  ? 93.276  118.281 134.165 1.00 79.87  ? 98  PHE H CD1 1 
ATOM 1542 C CD2 . PHE B 2 98  ? 93.993  116.371 135.390 1.00 79.87  ? 98  PHE H CD2 1 
ATOM 1543 C CE1 . PHE B 2 98  ? 93.372  119.051 135.304 1.00 79.87  ? 98  PHE H CE1 1 
ATOM 1544 C CE2 . PHE B 2 98  ? 94.090  117.136 136.533 1.00 79.87  ? 98  PHE H CE2 1 
ATOM 1545 C CZ  . PHE B 2 98  ? 93.779  118.478 136.490 1.00 79.87  ? 98  PHE H CZ  1 
ATOM 1546 N N   . CYS B 2 99  ? 92.017  116.378 130.296 1.00 77.60  ? 99  CYS H N   1 
ATOM 1547 C CA  . CYS B 2 99  ? 91.954  116.246 128.844 1.00 77.60  ? 99  CYS H CA  1 
ATOM 1548 C C   . CYS B 2 99  ? 93.019  117.149 128.245 1.00 77.60  ? 99  CYS H C   1 
ATOM 1549 O O   . CYS B 2 99  ? 93.046  118.349 128.532 1.00 77.60  ? 99  CYS H O   1 
ATOM 1550 C CB  . CYS B 2 99  ? 90.563  116.618 128.321 1.00 77.60  ? 99  CYS H CB  1 
ATOM 1551 S SG  . CYS B 2 99  ? 90.409  116.727 126.526 1.00 77.60  ? 99  CYS H SG  1 
ATOM 1552 N N   . SER B 2 100 ? 93.892  116.580 127.417 1.00 67.80  ? 100 SER H N   1 
ATOM 1553 C CA  . SER B 2 100 ? 95.060  117.289 126.915 1.00 67.80  ? 100 SER H CA  1 
ATOM 1554 C C   . SER B 2 100 ? 95.198  117.087 125.412 1.00 67.80  ? 100 SER H C   1 
ATOM 1555 O O   . SER B 2 100 ? 94.583  116.199 124.818 1.00 67.80  ? 100 SER H O   1 
ATOM 1556 C CB  . SER B 2 100 ? 96.337  116.826 127.626 1.00 67.80  ? 100 SER H CB  1 
ATOM 1557 O OG  . SER B 2 100 ? 97.489  117.237 126.913 1.00 67.80  ? 100 SER H OG  1 
ATOM 1558 N N   . THR B 2 101 ? 96.027  117.933 124.803 1.00 65.91  ? 101 THR H N   1 
ATOM 1559 C CA  . THR B 2 101 ? 96.301  117.862 123.375 1.00 65.91  ? 101 THR H CA  1 
ATOM 1560 C C   . THR B 2 101 ? 97.730  118.320 123.126 1.00 65.91  ? 101 THR H C   1 
ATOM 1561 O O   . THR B 2 101 ? 98.357  118.953 123.979 1.00 65.91  ? 101 THR H O   1 
ATOM 1562 C CB  . THR B 2 101 ? 95.318  118.714 122.564 1.00 65.91  ? 101 THR H CB  1 
ATOM 1563 O OG1 . THR B 2 101 ? 95.520  118.478 121.166 1.00 65.91  ? 101 THR H OG1 1 
ATOM 1564 C CG2 . THR B 2 101 ? 95.526  120.189 122.858 1.00 65.91  ? 101 THR H CG2 1 
ATOM 1565 N N   . GLY B 2 102 ? 98.241  117.988 121.947 1.00 63.16  ? 102 GLY H N   1 
ATOM 1566 C CA  . GLY B 2 102 ? 99.603  118.351 121.610 1.00 63.16  ? 102 GLY H CA  1 
ATOM 1567 C C   . GLY B 2 102 ? 99.969  117.848 120.232 1.00 63.16  ? 102 GLY H C   1 
ATOM 1568 O O   . GLY B 2 102 ? 99.129  117.329 119.494 1.00 63.16  ? 102 GLY H O   1 
ATOM 1569 N N   . TRP B 2 103 ? 101.246 118.011 119.892 1.00 55.81  ? 103 TRP H N   1 
ATOM 1570 C CA  . TRP B 2 103 ? 101.745 117.570 118.600 1.00 55.81  ? 103 TRP H CA  1 
ATOM 1571 C C   . TRP B 2 103 ? 101.851 116.046 118.567 1.00 55.81  ? 103 TRP H C   1 
ATOM 1572 O O   . TRP B 2 103 ? 101.515 115.347 119.526 1.00 55.81  ? 103 TRP H O   1 
ATOM 1573 C CB  . TRP B 2 103 ? 103.089 118.226 118.297 1.00 55.81  ? 103 TRP H CB  1 
ATOM 1574 C CG  . TRP B 2 103 ? 102.956 119.578 117.672 1.00 55.81  ? 103 TRP H CG  1 
ATOM 1575 C CD1 . TRP B 2 103 ? 103.283 120.776 118.232 1.00 55.81  ? 103 TRP H CD1 1 
ATOM 1576 C CD2 . TRP B 2 103 ? 102.461 119.869 116.361 1.00 55.81  ? 103 TRP H CD2 1 
ATOM 1577 N NE1 . TRP B 2 103 ? 103.020 121.797 117.353 1.00 55.81  ? 103 TRP H NE1 1 
ATOM 1578 C CE2 . TRP B 2 103 ? 102.515 121.266 116.195 1.00 55.81  ? 103 TRP H CE2 1 
ATOM 1579 C CE3 . TRP B 2 103 ? 101.977 119.085 115.311 1.00 55.81  ? 103 TRP H CE3 1 
ATOM 1580 C CZ2 . TRP B 2 103 ? 102.104 121.895 115.024 1.00 55.81  ? 103 TRP H CZ2 1 
ATOM 1581 C CZ3 . TRP B 2 103 ? 101.570 119.711 114.149 1.00 55.81  ? 103 TRP H CZ3 1 
ATOM 1582 C CH2 . TRP B 2 103 ? 101.636 121.101 114.015 1.00 55.81  ? 103 TRP H CH2 1 
ATOM 1583 N N   . ASP B 2 104 ? 102.329 115.528 117.432 1.00 60.76  ? 104 ASP H N   1 
ATOM 1584 C CA  . ASP B 2 104 ? 102.329 114.085 117.215 1.00 60.76  ? 104 ASP H CA  1 
ATOM 1585 C C   . ASP B 2 104 ? 103.216 113.372 118.230 1.00 60.76  ? 104 ASP H C   1 
ATOM 1586 O O   . ASP B 2 104 ? 102.816 112.356 118.810 1.00 60.76  ? 104 ASP H O   1 
ATOM 1587 C CB  . ASP B 2 104 ? 102.781 113.780 115.786 1.00 60.76  ? 104 ASP H CB  1 
ATOM 1588 C CG  . ASP B 2 104 ? 102.605 112.320 115.409 1.00 60.76  ? 104 ASP H CG  1 
ATOM 1589 O OD1 . ASP B 2 104 ? 102.158 111.522 116.258 1.00 60.76  ? 104 ASP H OD1 1 
ATOM 1590 O OD2 . ASP B 2 104 ? 102.914 111.970 114.251 1.00 60.76  ? 104 ASP H OD2 1 
ATOM 1591 N N   . TYR B 2 105 ? 104.420 113.895 118.467 1.00 56.26  ? 105 TYR H N   1 
ATOM 1592 C CA  . TYR B 2 105 ? 105.324 113.327 119.459 1.00 56.26  ? 105 TYR H CA  1 
ATOM 1593 C C   . TYR B 2 105 ? 105.843 114.372 120.437 1.00 56.26  ? 105 TYR H C   1 
ATOM 1594 O O   . TYR B 2 105 ? 106.719 114.059 121.250 1.00 56.26  ? 105 TYR H O   1 
ATOM 1595 C CB  . TYR B 2 105 ? 106.514 112.636 118.786 1.00 56.26  ? 105 TYR H CB  1 
ATOM 1596 C CG  . TYR B 2 105 ? 106.197 111.313 118.134 1.00 56.26  ? 105 TYR H CG  1 
ATOM 1597 C CD1 . TYR B 2 105 ? 106.074 110.158 118.890 1.00 56.26  ? 105 TYR H CD1 1 
ATOM 1598 C CD2 . TYR B 2 105 ? 106.046 111.215 116.758 1.00 56.26  ? 105 TYR H CD2 1 
ATOM 1599 C CE1 . TYR B 2 105 ? 105.793 108.945 118.297 1.00 56.26  ? 105 TYR H CE1 1 
ATOM 1600 C CE2 . TYR B 2 105 ? 105.766 110.006 116.156 1.00 56.26  ? 105 TYR H CE2 1 
ATOM 1601 C CZ  . TYR B 2 105 ? 105.640 108.875 116.930 1.00 56.26  ? 105 TYR H CZ  1 
ATOM 1602 O OH  . TYR B 2 105 ? 105.360 107.667 116.336 1.00 56.26  ? 105 TYR H OH  1 
ATOM 1603 N N   . GLY B 2 106 ? 105.336 115.599 120.380 1.00 52.61  ? 106 GLY H N   1 
ATOM 1604 C CA  . GLY B 2 106 ? 105.822 116.661 121.224 1.00 52.61  ? 106 GLY H CA  1 
ATOM 1605 C C   . GLY B 2 106 ? 105.177 116.656 122.593 1.00 52.61  ? 106 GLY H C   1 
ATOM 1606 O O   . GLY B 2 106 ? 104.411 115.754 122.944 1.00 52.61  ? 106 GLY H O   1 
ATOM 1607 N N   . PRO B 2 107 ? 105.479 117.673 123.396 1.00 54.60  ? 107 PRO H N   1 
ATOM 1608 C CA  . PRO B 2 107 ? 104.909 117.741 124.747 1.00 54.60  ? 107 PRO H CA  1 
ATOM 1609 C C   . PRO B 2 107 ? 103.438 118.119 124.736 1.00 54.60  ? 107 PRO H C   1 
ATOM 1610 O O   . PRO B 2 107 ? 102.864 118.378 123.674 1.00 54.60  ? 107 PRO H O   1 
ATOM 1611 C CB  . PRO B 2 107 ? 105.762 118.816 125.426 1.00 54.60  ? 107 PRO H CB  1 
ATOM 1612 C CG  . PRO B 2 107 ? 106.178 119.704 124.308 1.00 54.60  ? 107 PRO H CG  1 
ATOM 1613 C CD  . PRO B 2 107 ? 106.375 118.807 123.115 1.00 54.60  ? 107 PRO H CD  1 
ATOM 1614 N N   . PHE B 2 108 ? 102.821 118.154 125.913 1.00 58.07  ? 108 PHE H N   1 
ATOM 1615 C CA  . PHE B 2 108 ? 101.405 118.480 126.043 1.00 58.07  ? 108 PHE H CA  1 
ATOM 1616 C C   . PHE B 2 108 ? 101.271 119.997 126.109 1.00 58.07  ? 108 PHE H C   1 
ATOM 1617 O O   . PHE B 2 108 ? 101.685 120.622 127.090 1.00 58.07  ? 108 PHE H O   1 
ATOM 1618 C CB  . PHE B 2 108 ? 100.808 117.817 127.282 1.00 58.07  ? 108 PHE H CB  1 
ATOM 1619 C CG  . PHE B 2 108 ? 100.780 116.311 127.223 1.00 58.07  ? 108 PHE H CG  1 
ATOM 1620 C CD1 . PHE B 2 108 ? 101.207 115.628 126.097 1.00 58.07  ? 108 PHE H CD1 1 
ATOM 1621 C CD2 . PHE B 2 108 ? 100.323 115.578 128.305 1.00 58.07  ? 108 PHE H CD2 1 
ATOM 1622 C CE1 . PHE B 2 108 ? 101.182 114.249 126.054 1.00 58.07  ? 108 PHE H CE1 1 
ATOM 1623 C CE2 . PHE B 2 108 ? 100.293 114.200 128.265 1.00 58.07  ? 108 PHE H CE2 1 
ATOM 1624 C CZ  . PHE B 2 108 ? 100.722 113.535 127.138 1.00 58.07  ? 108 PHE H CZ  1 
ATOM 1625 N N   . ASP B 2 109 ? 100.684 120.589 125.068 1.00 63.23  ? 109 ASP H N   1 
ATOM 1626 C CA  . ASP B 2 109 ? 100.713 122.042 124.925 1.00 63.23  ? 109 ASP H CA  1 
ATOM 1627 C C   . ASP B 2 109 ? 99.780  122.723 125.918 1.00 63.23  ? 109 ASP H C   1 
ATOM 1628 O O   . ASP B 2 109 ? 100.227 123.467 126.799 1.00 63.23  ? 109 ASP H O   1 
ATOM 1629 C CB  . ASP B 2 109 ? 100.349 122.430 123.491 1.00 63.23  ? 109 ASP H CB  1 
ATOM 1630 C CG  . ASP B 2 109 ? 101.543 122.407 122.558 1.00 63.23  ? 109 ASP H CG  1 
ATOM 1631 O OD1 . ASP B 2 109 ? 102.688 122.400 123.056 1.00 63.23  ? 109 ASP H OD1 1 
ATOM 1632 O OD2 . ASP B 2 109 ? 101.336 122.398 121.326 1.00 63.23  ? 109 ASP H OD2 1 
ATOM 1633 N N   . SER B 2 110 ? 98.478  122.480 125.796 1.00 69.05  ? 110 SER H N   1 
ATOM 1634 C CA  . SER B 2 110 ? 97.478  123.189 126.582 1.00 69.05  ? 110 SER H CA  1 
ATOM 1635 C C   . SER B 2 110 ? 96.434  122.214 127.100 1.00 69.05  ? 110 SER H C   1 
ATOM 1636 O O   . SER B 2 110 ? 96.011  121.305 126.381 1.00 69.05  ? 110 SER H O   1 
ATOM 1637 C CB  . SER B 2 110 ? 96.799  124.282 125.751 1.00 69.05  ? 110 SER H CB  1 
ATOM 1638 O OG  . SER B 2 110 ? 96.376  123.775 124.498 1.00 69.05  ? 110 SER H OG  1 
ATOM 1639 N N   . TRP B 2 111 ? 96.018  122.410 128.350 1.00 69.45  ? 111 TRP H N   1 
ATOM 1640 C CA  . TRP B 2 111 ? 95.011  121.567 128.974 1.00 69.45  ? 111 TRP H CA  1 
ATOM 1641 C C   . TRP B 2 111 ? 93.798  122.405 129.350 1.00 69.45  ? 111 TRP H C   1 
ATOM 1642 O O   . TRP B 2 111 ? 93.888  123.627 129.498 1.00 69.45  ? 111 TRP H O   1 
ATOM 1643 C CB  . TRP B 2 111 ? 95.535  120.867 130.239 1.00 69.45  ? 111 TRP H CB  1 
ATOM 1644 C CG  . TRP B 2 111 ? 96.720  119.976 130.033 1.00 69.45  ? 111 TRP H CG  1 
ATOM 1645 C CD1 . TRP B 2 111 ? 97.451  119.831 128.894 1.00 69.45  ? 111 TRP H CD1 1 
ATOM 1646 C CD2 . TRP B 2 111 ? 97.271  119.054 130.981 1.00 69.45  ? 111 TRP H CD2 1 
ATOM 1647 N NE1 . TRP B 2 111 ? 98.447  118.909 129.085 1.00 69.45  ? 111 TRP H NE1 1 
ATOM 1648 C CE2 . TRP B 2 111 ? 98.354  118.411 130.356 1.00 69.45  ? 111 TRP H CE2 1 
ATOM 1649 C CE3 . TRP B 2 111 ? 96.960  118.720 132.300 1.00 69.45  ? 111 TRP H CE3 1 
ATOM 1650 C CZ2 . TRP B 2 111 ? 99.128  117.455 131.004 1.00 69.45  ? 111 TRP H CZ2 1 
ATOM 1651 C CZ3 . TRP B 2 111 ? 97.728  117.768 132.941 1.00 69.45  ? 111 TRP H CZ3 1 
ATOM 1652 C CH2 . TRP B 2 111 ? 98.801  117.148 132.294 1.00 69.45  ? 111 TRP H CH2 1 
ATOM 1653 N N   . GLY B 2 112 ? 92.659  121.733 129.502 1.00 82.93  ? 112 GLY H N   1 
ATOM 1654 C CA  . GLY B 2 112 ? 91.470  122.348 130.044 1.00 82.93  ? 112 GLY H CA  1 
ATOM 1655 C C   . GLY B 2 112 ? 91.222  121.898 131.476 1.00 82.93  ? 112 GLY H C   1 
ATOM 1656 O O   . GLY B 2 112 ? 91.879  121.002 131.997 1.00 82.93  ? 112 GLY H O   1 
ATOM 1657 N N   . GLN B 2 113 ? 90.253  122.549 132.115 1.00 94.66  ? 113 GLN H N   1 
ATOM 1658 C CA  . GLN B 2 113 ? 89.909  122.168 133.475 1.00 94.66  ? 113 GLN H CA  1 
ATOM 1659 C C   . GLN B 2 113 ? 89.293  120.772 133.485 1.00 94.66  ? 113 GLN H C   1 
ATOM 1660 O O   . GLN B 2 113 ? 88.685  120.321 132.510 1.00 94.66  ? 113 GLN H O   1 
ATOM 1661 C CB  . GLN B 2 113 ? 88.949  123.179 134.105 1.00 94.66  ? 113 GLN H CB  1 
ATOM 1662 C CG  . GLN B 2 113 ? 87.520  123.131 133.583 1.00 94.66  ? 113 GLN H CG  1 
ATOM 1663 C CD  . GLN B 2 113 ? 87.359  123.767 132.218 1.00 94.66  ? 113 GLN H CD  1 
ATOM 1664 O OE1 . GLN B 2 113 ? 88.320  124.265 131.631 1.00 94.66  ? 113 GLN H OE1 1 
ATOM 1665 N NE2 . GLN B 2 113 ? 86.134  123.760 131.708 1.00 94.66  ? 113 GLN H NE2 1 
ATOM 1666 N N   . GLY B 2 114 ? 89.468  120.079 134.605 1.00 95.18  ? 114 GLY H N   1 
ATOM 1667 C CA  . GLY B 2 114 ? 89.078  118.688 134.727 1.00 95.18  ? 114 GLY H CA  1 
ATOM 1668 C C   . GLY B 2 114 ? 87.798  118.520 135.523 1.00 95.18  ? 114 GLY H C   1 
ATOM 1669 O O   . GLY B 2 114 ? 87.571  119.215 136.515 1.00 95.18  ? 114 GLY H O   1 
ATOM 1670 N N   . THR B 2 115 ? 86.961  117.589 135.076 1.00 99.50  ? 115 THR H N   1 
ATOM 1671 C CA  . THR B 2 115 ? 85.756  117.245 135.811 1.00 99.50  ? 115 THR H CA  1 
ATOM 1672 C C   . THR B 2 115 ? 86.085  116.288 136.951 1.00 99.50  ? 115 THR H C   1 
ATOM 1673 O O   . THR B 2 115 ? 86.916  115.387 136.815 1.00 99.50  ? 115 THR H O   1 
ATOM 1674 C CB  . THR B 2 115 ? 84.726  116.608 134.881 1.00 99.50  ? 115 THR H CB  1 
ATOM 1675 O OG1 . THR B 2 115 ? 85.226  115.352 134.407 1.00 99.50  ? 115 THR H OG1 1 
ATOM 1676 C CG2 . THR B 2 115 ? 84.461  117.516 133.693 1.00 99.50  ? 115 THR H CG2 1 
ATOM 1677 N N   . THR B 2 116 ? 85.415  116.485 138.081 1.00 101.86 ? 116 THR H N   1 
ATOM 1678 C CA  . THR B 2 116 ? 85.638  115.682 139.272 1.00 101.86 ? 116 THR H CA  1 
ATOM 1679 C C   . THR B 2 116 ? 84.504  114.681 139.452 1.00 101.86 ? 116 THR H C   1 
ATOM 1680 O O   . THR B 2 116 ? 83.358  114.936 139.073 1.00 101.86 ? 116 THR H O   1 
ATOM 1681 C CB  . THR B 2 116 ? 85.762  116.563 140.520 1.00 101.86 ? 116 THR H CB  1 
ATOM 1682 O OG1 . THR B 2 116 ? 86.002  115.739 141.668 1.00 101.86 ? 116 THR H OG1 1 
ATOM 1683 C CG2 . THR B 2 116 ? 84.496  117.378 140.736 1.00 101.86 ? 116 THR H CG2 1 
ATOM 1684 N N   . LEU B 2 117 ? 84.841  113.529 140.022 1.00 103.17 ? 117 LEU H N   1 
ATOM 1685 C CA  . LEU B 2 117 ? 83.866  112.467 140.240 1.00 103.17 ? 117 LEU H CA  1 
ATOM 1686 C C   . LEU B 2 117 ? 83.689  112.183 141.728 1.00 103.17 ? 117 LEU H C   1 
ATOM 1687 O O   . LEU B 2 117 ? 82.861  111.360 142.119 1.00 103.17 ? 117 LEU H O   1 
ATOM 1688 C CB  . LEU B 2 117 ? 84.289  111.193 139.507 1.00 103.17 ? 117 LEU H CB  1 
ATOM 1689 C CG  . LEU B 2 117 ? 83.618  110.930 138.157 1.00 103.17 ? 117 LEU H CG  1 
ATOM 1690 C CD1 . LEU B 2 117 ? 83.922  112.048 137.174 1.00 103.17 ? 117 LEU H CD1 1 
ATOM 1691 C CD2 . LEU B 2 117 ? 84.051  109.588 137.594 1.00 103.17 ? 117 LEU H CD2 1 
ATOM 1692 N N   . ALA C 3 2   ? 115.986 141.429 105.622 1.00 73.98  ? 1   ALA C N   1 
ATOM 1693 C CA  . ALA C 3 2   ? 116.834 142.162 106.553 1.00 73.98  ? 1   ALA C CA  1 
ATOM 1694 C C   . ALA C 3 2   ? 118.131 142.592 105.881 1.00 73.98  ? 1   ALA C C   1 
ATOM 1695 O O   . ALA C 3 2   ? 118.646 141.897 105.006 1.00 73.98  ? 1   ALA C O   1 
ATOM 1696 C CB  . ALA C 3 2   ? 117.129 141.317 107.780 1.00 73.98  ? 1   ALA C CB  1 
ATOM 1697 N N   . LYS C 3 3   ? 118.655 143.742 106.294 1.00 74.06  ? 2   LYS C N   1 
ATOM 1698 C CA  . LYS C 3 3   ? 119.898 144.241 105.728 1.00 74.06  ? 2   LYS C CA  1 
ATOM 1699 C C   . LYS C 3 3   ? 121.076 143.391 106.190 1.00 74.06  ? 2   LYS C C   1 
ATOM 1700 O O   . LYS C 3 3   ? 121.034 142.749 107.242 1.00 74.06  ? 2   LYS C O   1 
ATOM 1701 C CB  . LYS C 3 3   ? 120.118 145.701 106.121 1.00 74.06  ? 2   LYS C CB  1 
ATOM 1702 C CG  . LYS C 3 3   ? 119.904 145.986 107.597 1.00 74.06  ? 2   LYS C CG  1 
ATOM 1703 C CD  . LYS C 3 3   ? 119.803 147.479 107.856 1.00 74.06  ? 2   LYS C CD  1 
ATOM 1704 C CE  . LYS C 3 3   ? 121.040 148.211 107.362 1.00 74.06  ? 2   LYS C CE  1 
ATOM 1705 N NZ  . LYS C 3 3   ? 122.166 148.114 108.330 1.00 74.06  ? 2   LYS C NZ  1 
ATOM 1706 N N   . LEU C 3 4   ? 122.132 143.387 105.382 1.00 69.93  ? 3   LEU C N   1 
ATOM 1707 C CA  . LEU C 3 4   ? 123.314 142.601 105.699 1.00 69.93  ? 3   LEU C CA  1 
ATOM 1708 C C   . LEU C 3 4   ? 123.993 143.132 106.955 1.00 69.93  ? 3   LEU C C   1 
ATOM 1709 O O   . LEU C 3 4   ? 124.049 144.342 107.189 1.00 69.93  ? 3   LEU C O   1 
ATOM 1710 C CB  . LEU C 3 4   ? 124.294 142.616 104.528 1.00 69.93  ? 3   LEU C CB  1 
ATOM 1711 C CG  . LEU C 3 4   ? 123.912 141.774 103.310 1.00 69.93  ? 3   LEU C CG  1 
ATOM 1712 C CD1 . LEU C 3 4   ? 124.832 142.079 102.140 1.00 69.93  ? 3   LEU C CD1 1 
ATOM 1713 C CD2 . LEU C 3 4   ? 123.944 140.294 103.650 1.00 69.93  ? 3   LEU C CD2 1 
ATOM 1714 N N   . GLU C 3 5   ? 124.512 142.212 107.764 1.00 68.61  ? 4   GLU C N   1 
ATOM 1715 C CA  . GLU C 3 5   ? 125.203 142.559 108.996 1.00 68.61  ? 4   GLU C CA  1 
ATOM 1716 C C   . GLU C 3 5   ? 126.214 141.466 109.307 1.00 68.61  ? 4   GLU C C   1 
ATOM 1717 O O   . GLU C 3 5   ? 126.193 140.386 108.713 1.00 68.61  ? 4   GLU C O   1 
ATOM 1718 C CB  . GLU C 3 5   ? 124.223 142.745 110.160 1.00 68.61  ? 4   GLU C CB  1 
ATOM 1719 C CG  . GLU C 3 5   ? 123.777 144.181 110.376 1.00 68.61  ? 4   GLU C CG  1 
ATOM 1720 C CD  . GLU C 3 5   ? 122.584 144.285 111.305 1.00 68.61  ? 4   GLU C CD  1 
ATOM 1721 O OE1 . GLU C 3 5   ? 122.113 143.235 111.789 1.00 68.61  ? 4   GLU C OE1 1 
ATOM 1722 O OE2 . GLU C 3 5   ? 122.118 145.417 111.550 1.00 68.61  ? 4   GLU C OE2 1 
ATOM 1723 N N   . THR C 3 6   ? 127.112 141.764 110.243 1.00 59.22  ? 5   THR C N   1 
ATOM 1724 C CA  . THR C 3 6   ? 128.116 140.790 110.650 1.00 59.22  ? 5   THR C CA  1 
ATOM 1725 C C   . THR C 3 6   ? 127.447 139.556 111.241 1.00 59.22  ? 5   THR C C   1 
ATOM 1726 O O   . THR C 3 6   ? 126.586 139.661 112.119 1.00 59.22  ? 5   THR C O   1 
ATOM 1727 C CB  . THR C 3 6   ? 129.074 141.412 111.665 1.00 59.22  ? 5   THR C CB  1 
ATOM 1728 O OG1 . THR C 3 6   ? 129.791 142.489 111.051 1.00 59.22  ? 5   THR C OG1 1 
ATOM 1729 C CG2 . THR C 3 6   ? 130.066 140.375 112.169 1.00 59.22  ? 5   THR C CG2 1 
ATOM 1730 N N   . VAL C 3 7   ? 127.847 138.384 110.756 1.00 55.62  ? 6   VAL C N   1 
ATOM 1731 C CA  . VAL C 3 7   ? 127.286 137.110 111.185 1.00 55.62  ? 6   VAL C CA  1 
ATOM 1732 C C   . VAL C 3 7   ? 128.405 136.276 111.791 1.00 55.62  ? 6   VAL C C   1 
ATOM 1733 O O   . VAL C 3 7   ? 129.456 136.095 111.167 1.00 55.62  ? 6   VAL C O   1 
ATOM 1734 C CB  . VAL C 3 7   ? 126.620 136.359 110.017 1.00 55.62  ? 6   VAL C CB  1 
ATOM 1735 C CG1 . VAL C 3 7   ? 126.017 135.053 110.502 1.00 55.62  ? 6   VAL C CG1 1 
ATOM 1736 C CG2 . VAL C 3 7   ? 125.563 137.230 109.362 1.00 55.62  ? 6   VAL C CG2 1 
ATOM 1737 N N   . THR C 3 8   ? 128.180 135.777 113.001 1.00 57.84  ? 7   THR C N   1 
ATOM 1738 C CA  . THR C 3 8   ? 129.139 134.929 113.691 1.00 57.84  ? 7   THR C CA  1 
ATOM 1739 C C   . THR C 3 8   ? 128.559 133.532 113.867 1.00 57.84  ? 7   THR C C   1 
ATOM 1740 O O   . THR C 3 8   ? 127.380 133.374 114.201 1.00 57.84  ? 7   THR C O   1 
ATOM 1741 C CB  . THR C 3 8   ? 129.528 135.524 115.049 1.00 57.84  ? 7   THR C CB  1 
ATOM 1742 O OG1 . THR C 3 8   ? 130.400 134.620 115.741 1.00 57.84  ? 7   THR C OG1 1 
ATOM 1743 C CG2 . THR C 3 8   ? 128.295 135.801 115.900 1.00 57.84  ? 7   THR C CG2 1 
ATOM 1744 N N   . LEU C 3 9   ? 129.386 132.520 113.621 1.00 57.71  ? 8   LEU C N   1 
ATOM 1745 C CA  . LEU C 3 9   ? 128.977 131.125 113.694 1.00 57.71  ? 8   LEU C CA  1 
ATOM 1746 C C   . LEU C 3 9   ? 129.775 130.423 114.781 1.00 57.71  ? 8   LEU C C   1 
ATOM 1747 O O   . LEU C 3 9   ? 131.001 130.561 114.843 1.00 57.71  ? 8   LEU C O   1 
ATOM 1748 C CB  . LEU C 3 9   ? 129.178 130.422 112.350 1.00 57.71  ? 8   LEU C CB  1 
ATOM 1749 C CG  . LEU C 3 9   ? 128.385 130.988 111.173 1.00 57.71  ? 8   LEU C CG  1 
ATOM 1750 C CD1 . LEU C 3 9   ? 129.004 130.560 109.853 1.00 57.71  ? 8   LEU C CD1 1 
ATOM 1751 C CD2 . LEU C 3 9   ? 126.933 130.557 111.251 1.00 57.71  ? 8   LEU C CD2 1 
ATOM 1752 N N   . GLY C 3 10  ? 129.082 129.671 115.631 1.00 64.33  ? 9   GLY C N   1 
ATOM 1753 C CA  . GLY C 3 10  ? 129.733 128.966 116.717 1.00 64.33  ? 9   GLY C CA  1 
ATOM 1754 C C   . GLY C 3 10  ? 129.650 127.460 116.596 1.00 64.33  ? 9   GLY C C   1 
ATOM 1755 O O   . GLY C 3 10  ? 128.808 126.935 115.860 1.00 64.33  ? 9   GLY C O   1 
ATOM 1756 N N   . LYS C 3 11  ? 130.527 126.758 117.317 1.00 70.04  ? 10  LYS C N   1 
ATOM 1757 C CA  . LYS C 3 11  ? 130.559 125.294 117.335 1.00 70.04  ? 10  LYS C CA  1 
ATOM 1758 C C   . LYS C 3 11  ? 130.760 124.723 115.932 1.00 70.04  ? 10  LYS C C   1 
ATOM 1759 O O   . LYS C 3 11  ? 130.165 123.710 115.561 1.00 70.04  ? 10  LYS C O   1 
ATOM 1760 C CB  . LYS C 3 11  ? 129.294 124.721 117.980 1.00 70.04  ? 10  LYS C CB  1 
ATOM 1761 C CG  . LYS C 3 11  ? 129.049 125.134 119.436 1.00 70.04  ? 10  LYS C CG  1 
ATOM 1762 C CD  . LYS C 3 11  ? 130.028 124.502 120.426 1.00 70.04  ? 10  LYS C CD  1 
ATOM 1763 C CE  . LYS C 3 11  ? 131.230 125.397 120.712 1.00 70.04  ? 10  LYS C CE  1 
ATOM 1764 N NZ  . LYS C 3 11  ? 132.120 124.820 121.757 1.00 70.04  ? 10  LYS C NZ  1 
ATOM 1765 N N   . ILE C 3 12  ? 131.603 125.378 115.150 1.00 65.69  ? 11  ILE C N   1 
ATOM 1766 C CA  . ILE C 3 12  ? 131.923 124.954 113.793 1.00 65.69  ? 11  ILE C CA  1 
ATOM 1767 C C   . ILE C 3 12  ? 133.146 124.051 113.834 1.00 65.69  ? 11  ILE C C   1 
ATOM 1768 O O   . ILE C 3 12  ? 134.074 124.264 114.620 1.00 65.69  ? 11  ILE C O   1 
ATOM 1769 C CB  . ILE C 3 12  ? 132.152 126.177 112.880 1.00 65.69  ? 11  ILE C CB  1 
ATOM 1770 C CG1 . ILE C 3 12  ? 130.908 127.060 112.856 1.00 65.69  ? 11  ILE C CG1 1 
ATOM 1771 C CG2 . ILE C 3 12  ? 132.506 125.746 111.468 1.00 65.69  ? 11  ILE C CG2 1 
ATOM 1772 C CD1 . ILE C 3 12  ? 129.693 126.360 112.318 1.00 65.69  ? 11  ILE C CD1 1 
ATOM 1773 N N   . GLY C 3 13  ? 133.149 123.027 112.993 1.00 62.28  ? 12  GLY C N   1 
ATOM 1774 C CA  . GLY C 3 13  ? 134.294 122.152 112.843 1.00 62.28  ? 12  GLY C CA  1 
ATOM 1775 C C   . GLY C 3 13  ? 133.957 120.705 113.153 1.00 62.28  ? 12  GLY C C   1 
ATOM 1776 O O   . GLY C 3 13  ? 132.864 120.364 113.601 1.00 62.28  ? 12  GLY C O   1 
ATOM 1777 N N   . LYS C 3 14  ? 134.947 119.849 112.889 1.00 67.05  ? 13  LYS C N   1 
ATOM 1778 C CA  . LYS C 3 14  ? 134.785 118.423 113.155 1.00 67.05  ? 13  LYS C CA  1 
ATOM 1779 C C   . LYS C 3 14  ? 134.615 118.153 114.645 1.00 67.05  ? 13  LYS C C   1 
ATOM 1780 O O   . LYS C 3 14  ? 133.768 117.346 115.045 1.00 67.05  ? 13  LYS C O   1 
ATOM 1781 C CB  . LYS C 3 14  ? 135.982 117.652 112.600 1.00 67.05  ? 13  LYS C CB  1 
ATOM 1782 C CG  . LYS C 3 14  ? 135.984 116.173 112.942 1.00 67.05  ? 13  LYS C CG  1 
ATOM 1783 C CD  . LYS C 3 14  ? 137.385 115.593 112.862 1.00 67.05  ? 13  LYS C CD  1 
ATOM 1784 C CE  . LYS C 3 14  ? 137.355 114.132 112.446 1.00 67.05  ? 13  LYS C CE  1 
ATOM 1785 N NZ  . LYS C 3 14  ? 137.015 113.977 111.005 1.00 67.05  ? 13  LYS C NZ  1 
ATOM 1786 N N   . ASP C 3 15  ? 135.407 118.820 115.481 1.00 73.92  ? 14  ASP C N   1 
ATOM 1787 C CA  . ASP C 3 15  ? 135.328 118.654 116.926 1.00 73.92  ? 14  ASP C CA  1 
ATOM 1788 C C   . ASP C 3 15  ? 134.402 119.664 117.590 1.00 73.92  ? 14  ASP C C   1 
ATOM 1789 O O   . ASP C 3 15  ? 134.227 119.611 118.811 1.00 73.92  ? 14  ASP C O   1 
ATOM 1790 C CB  . ASP C 3 15  ? 136.726 118.754 117.546 1.00 73.92  ? 14  ASP C CB  1 
ATOM 1791 C CG  . ASP C 3 15  ? 137.549 119.881 116.954 1.00 73.92  ? 14  ASP C CG  1 
ATOM 1792 O OD1 . ASP C 3 15  ? 136.957 120.880 116.495 1.00 73.92  ? 14  ASP C OD1 1 
ATOM 1793 O OD2 . ASP C 3 15  ? 138.793 119.770 116.950 1.00 73.92  ? 14  ASP C OD2 1 
ATOM 1794 N N   . GLY C 3 16  ? 133.808 120.572 116.824 1.00 71.80  ? 15  GLY C N   1 
ATOM 1795 C CA  . GLY C 3 16  ? 132.903 121.559 117.388 1.00 71.80  ? 15  GLY C CA  1 
ATOM 1796 C C   . GLY C 3 16  ? 133.558 122.553 118.321 1.00 71.80  ? 15  GLY C C   1 
ATOM 1797 O O   . GLY C 3 16  ? 132.995 122.867 119.378 1.00 71.80  ? 15  GLY C O   1 
ATOM 1798 N N   . LYS C 3 17  ? 134.737 123.060 117.960 1.00 71.70  ? 16  LYS C N   1 
ATOM 1799 C CA  . LYS C 3 17  ? 135.439 124.037 118.778 1.00 71.70  ? 16  LYS C CA  1 
ATOM 1800 C C   . LYS C 3 17  ? 135.883 125.278 118.019 1.00 71.70  ? 16  LYS C C   1 
ATOM 1801 O O   . LYS C 3 17  ? 136.207 126.284 118.660 1.00 71.70  ? 16  LYS C O   1 
ATOM 1802 C CB  . LYS C 3 17  ? 136.668 123.397 119.443 1.00 71.70  ? 16  LYS C CB  1 
ATOM 1803 C CG  . LYS C 3 17  ? 136.330 122.399 120.537 1.00 71.70  ? 16  LYS C CG  1 
ATOM 1804 C CD  . LYS C 3 17  ? 137.564 121.641 120.994 1.00 71.70  ? 16  LYS C CD  1 
ATOM 1805 C CE  . LYS C 3 17  ? 137.357 121.029 122.369 1.00 71.70  ? 16  LYS C CE  1 
ATOM 1806 N NZ  . LYS C 3 17  ? 135.923 121.038 122.771 1.00 71.70  ? 16  LYS C NZ  1 
ATOM 1807 N N   . GLN C 3 18  ? 135.909 125.246 116.689 1.00 67.90  ? 17  GLN C N   1 
ATOM 1808 C CA  . GLN C 3 18  ? 136.321 126.406 115.917 1.00 67.90  ? 17  GLN C CA  1 
ATOM 1809 C C   . GLN C 3 18  ? 135.205 127.449 115.896 1.00 67.90  ? 17  GLN C C   1 
ATOM 1810 O O   . GLN C 3 18  ? 134.094 127.225 116.383 1.00 67.90  ? 17  GLN C O   1 
ATOM 1811 C CB  . GLN C 3 18  ? 136.714 125.992 114.501 1.00 67.90  ? 17  GLN C CB  1 
ATOM 1812 C CG  . GLN C 3 18  ? 137.965 125.137 114.430 1.00 67.90  ? 17  GLN C CG  1 
ATOM 1813 C CD  . GLN C 3 18  ? 137.883 124.077 113.351 1.00 67.90  ? 17  GLN C CD  1 
ATOM 1814 O OE1 . GLN C 3 18  ? 137.431 122.959 113.597 1.00 67.90  ? 17  GLN C OE1 1 
ATOM 1815 N NE2 . GLN C 3 18  ? 138.320 124.424 112.147 1.00 67.90  ? 17  GLN C NE2 1 
ATOM 1816 N N   . THR C 3 19  ? 135.509 128.610 115.322 1.00 66.23  ? 18  THR C N   1 
ATOM 1817 C CA  . THR C 3 19  ? 134.546 129.699 115.228 1.00 66.23  ? 18  THR C CA  1 
ATOM 1818 C C   . THR C 3 19  ? 134.813 130.471 113.946 1.00 66.23  ? 18  THR C C   1 
ATOM 1819 O O   . THR C 3 19  ? 135.963 130.813 113.658 1.00 66.23  ? 18  THR C O   1 
ATOM 1820 C CB  . THR C 3 19  ? 134.640 130.630 116.442 1.00 66.23  ? 18  THR C CB  1 
ATOM 1821 O OG1 . THR C 3 19  ? 134.349 129.893 117.636 1.00 66.23  ? 18  THR C OG1 1 
ATOM 1822 C CG2 . THR C 3 19  ? 133.656 131.783 116.313 1.00 66.23  ? 18  THR C CG2 1 
ATOM 1823 N N   . LEU C 3 20  ? 133.757 130.740 113.184 1.00 59.15  ? 19  LEU C N   1 
ATOM 1824 C CA  . LEU C 3 20  ? 133.860 131.447 111.915 1.00 59.15  ? 19  LEU C CA  1 
ATOM 1825 C C   . LEU C 3 20  ? 133.046 132.728 111.997 1.00 59.15  ? 19  LEU C C   1 
ATOM 1826 O O   . LEU C 3 20  ? 131.842 132.685 112.267 1.00 59.15  ? 19  LEU C O   1 
ATOM 1827 C CB  . LEU C 3 20  ? 133.370 130.574 110.759 1.00 59.15  ? 19  LEU C CB  1 
ATOM 1828 C CG  . LEU C 3 20  ? 133.202 131.279 109.414 1.00 59.15  ? 19  LEU C CG  1 
ATOM 1829 C CD1 . LEU C 3 20  ? 134.544 131.761 108.892 1.00 59.15  ? 19  LEU C CD1 1 
ATOM 1830 C CD2 . LEU C 3 20  ? 132.530 130.359 108.411 1.00 59.15  ? 19  LEU C CD2 1 
ATOM 1831 N N   . VAL C 3 21  ? 133.702 133.861 111.762 1.00 56.11  ? 20  VAL C N   1 
ATOM 1832 C CA  . VAL C 3 21  ? 133.056 135.168 111.754 1.00 56.11  ? 20  VAL C CA  1 
ATOM 1833 C C   . VAL C 3 21  ? 133.275 135.800 110.387 1.00 56.11  ? 20  VAL C C   1 
ATOM 1834 O O   . VAL C 3 21  ? 134.401 135.817 109.876 1.00 56.11  ? 20  VAL C O   1 
ATOM 1835 C CB  . VAL C 3 21  ? 133.580 136.072 112.887 1.00 56.11  ? 20  VAL C CB  1 
ATOM 1836 C CG1 . VAL C 3 21  ? 135.089 136.249 112.797 1.00 56.11  ? 20  VAL C CG1 1 
ATOM 1837 C CG2 . VAL C 3 21  ? 132.881 137.421 112.853 1.00 56.11  ? 20  VAL C CG2 1 
ATOM 1838 N N   . LEU C 3 22  ? 132.196 136.291 109.786 1.00 52.61  ? 21  LEU C N   1 
ATOM 1839 C CA  . LEU C 3 22  ? 132.247 136.840 108.441 1.00 52.61  ? 21  LEU C CA  1 
ATOM 1840 C C   . LEU C 3 22  ? 131.360 138.073 108.362 1.00 52.61  ? 21  LEU C C   1 
ATOM 1841 O O   . LEU C 3 22  ? 130.346 138.172 109.056 1.00 52.61  ? 21  LEU C O   1 
ATOM 1842 C CB  . LEU C 3 22  ? 131.836 135.789 107.396 1.00 52.61  ? 21  LEU C CB  1 
ATOM 1843 C CG  . LEU C 3 22  ? 130.384 135.321 107.281 1.00 52.61  ? 21  LEU C CG  1 
ATOM 1844 C CD1 . LEU C 3 22  ? 130.201 134.563 105.983 1.00 52.61  ? 21  LEU C CD1 1 
ATOM 1845 C CD2 . LEU C 3 22  ? 129.980 134.442 108.449 1.00 52.61  ? 21  LEU C CD2 1 
ATOM 1846 N N   . ASN C 3 23  ? 131.752 139.008 107.508 1.00 52.27  ? 22  ASN C N   1 
ATOM 1847 C CA  . ASN C 3 23  ? 131.150 140.328 107.417 1.00 52.27  ? 22  ASN C CA  1 
ATOM 1848 C C   . ASN C 3 23  ? 130.697 140.610 105.993 1.00 52.27  ? 22  ASN C C   1 
ATOM 1849 O O   . ASN C 3 23  ? 131.189 139.994 105.043 1.00 52.27  ? 22  ASN C O   1 
ATOM 1850 C CB  . ASN C 3 23  ? 132.138 141.405 107.897 1.00 52.27  ? 22  ASN C CB  1 
ATOM 1851 C CG  . ASN C 3 23  ? 133.445 141.402 107.123 1.00 52.27  ? 22  ASN C CG  1 
ATOM 1852 O OD1 . ASN C 3 23  ? 133.608 140.673 106.147 1.00 52.27  ? 22  ASN C OD1 1 
ATOM 1853 N ND2 . ASN C 3 23  ? 134.389 142.223 107.565 1.00 52.27  ? 22  ASN C ND2 1 
ATOM 1854 N N   . PRO C 3 24  ? 129.740 141.525 105.812 1.00 51.55  ? 23  PRO C N   1 
ATOM 1855 C CA  . PRO C 3 24  ? 129.198 141.769 104.470 1.00 51.55  ? 23  PRO C CA  1 
ATOM 1856 C C   . PRO C 3 24  ? 130.239 142.334 103.516 1.00 51.55  ? 23  PRO C C   1 
ATOM 1857 O O   . PRO C 3 24  ? 131.195 142.998 103.921 1.00 51.55  ? 23  PRO C O   1 
ATOM 1858 C CB  . PRO C 3 24  ? 128.070 142.777 104.721 1.00 51.55  ? 23  PRO C CB  1 
ATOM 1859 C CG  . PRO C 3 24  ? 128.410 143.407 106.025 1.00 51.55  ? 23  PRO C CG  1 
ATOM 1860 C CD  . PRO C 3 24  ? 129.028 142.313 106.831 1.00 51.55  ? 23  PRO C CD  1 
ATOM 1861 N N   . ARG C 3 25  ? 130.036 142.057 102.229 1.00 51.31  ? 24  ARG C N   1 
ATOM 1862 C CA  . ARG C 3 25  ? 130.942 142.481 101.168 1.00 51.31  ? 24  ARG C CA  1 
ATOM 1863 C C   . ARG C 3 25  ? 130.152 143.043 99.991  1.00 51.31  ? 24  ARG C C   1 
ATOM 1864 O O   . ARG C 3 25  ? 130.471 142.791 98.825  1.00 51.31  ? 24  ARG C O   1 
ATOM 1865 C CB  . ARG C 3 25  ? 131.843 141.327 100.725 1.00 51.31  ? 24  ARG C CB  1 
ATOM 1866 C CG  . ARG C 3 25  ? 133.106 141.744 99.987  1.00 51.31  ? 24  ARG C CG  1 
ATOM 1867 C CD  . ARG C 3 25  ? 133.949 142.698 100.812 1.00 51.31  ? 24  ARG C CD  1 
ATOM 1868 N NE  . ARG C 3 25  ? 134.420 142.096 102.053 1.00 51.31  ? 24  ARG C NE  1 
ATOM 1869 C CZ  . ARG C 3 25  ? 135.576 141.460 102.183 1.00 51.31  ? 24  ARG C CZ  1 
ATOM 1870 N NH1 . ARG C 3 25  ? 136.398 141.305 101.158 1.00 51.31  ? 24  ARG C NH1 1 
ATOM 1871 N NH2 . ARG C 3 25  ? 135.918 140.972 103.371 1.00 51.31  ? 24  ARG C NH2 1 
ATOM 1872 N N   . GLY C 3 26  ? 129.101 143.805 100.282 1.00 52.51  ? 25  GLY C N   1 
ATOM 1873 C CA  . GLY C 3 26  ? 128.362 144.502 99.248  1.00 52.51  ? 25  GLY C CA  1 
ATOM 1874 C C   . GLY C 3 26  ? 127.322 143.642 98.554  1.00 52.51  ? 25  GLY C C   1 
ATOM 1875 O O   . GLY C 3 26  ? 127.150 142.454 98.828  1.00 52.51  ? 25  GLY C O   1 
ATOM 1876 N N   . VAL C 3 27  ? 126.608 144.280 97.627  1.00 59.08  ? 26  VAL C N   1 
ATOM 1877 C CA  . VAL C 3 27  ? 125.545 143.646 96.856  1.00 59.08  ? 26  VAL C CA  1 
ATOM 1878 C C   . VAL C 3 27  ? 125.792 143.919 95.379  1.00 59.08  ? 26  VAL C C   1 
ATOM 1879 O O   . VAL C 3 27  ? 125.996 145.072 94.984  1.00 59.08  ? 26  VAL C O   1 
ATOM 1880 C CB  . VAL C 3 27  ? 124.153 144.160 97.273  1.00 59.08  ? 26  VAL C CB  1 
ATOM 1881 C CG1 . VAL C 3 27  ? 123.090 143.660 96.310  1.00 59.08  ? 26  VAL C CG1 1 
ATOM 1882 C CG2 . VAL C 3 27  ? 123.834 143.732 98.694  1.00 59.08  ? 26  VAL C CG2 1 
ATOM 1883 N N   . ASN C 3 28  ? 125.767 142.867 94.570  1.00 64.21  ? 27  ASN C N   1 
ATOM 1884 C CA  . ASN C 3 28  ? 125.970 143.013 93.133  1.00 64.21  ? 27  ASN C CA  1 
ATOM 1885 C C   . ASN C 3 28  ? 124.689 143.522 92.482  1.00 64.21  ? 27  ASN C C   1 
ATOM 1886 O O   . ASN C 3 28  ? 123.652 142.857 92.581  1.00 64.21  ? 27  ASN C O   1 
ATOM 1887 C CB  . ASN C 3 28  ? 126.382 141.682 92.520  1.00 64.21  ? 27  ASN C CB  1 
ATOM 1888 C CG  . ASN C 3 28  ? 126.609 141.771 91.025  1.00 64.21  ? 27  ASN C CG  1 
ATOM 1889 O OD1 . ASN C 3 28  ? 126.897 142.840 90.490  1.00 64.21  ? 27  ASN C OD1 1 
ATOM 1890 N ND2 . ASN C 3 28  ? 126.480 140.641 90.341  1.00 64.21  ? 27  ASN C ND2 1 
ATOM 1891 N N   . PRO C 3 29  ? 124.711 144.679 91.812  1.00 67.52  ? 28  PRO C N   1 
ATOM 1892 C CA  . PRO C 3 29  ? 123.470 145.207 91.225  1.00 67.52  ? 28  PRO C CA  1 
ATOM 1893 C C   . PRO C 3 29  ? 123.045 144.523 89.938  1.00 67.52  ? 28  PRO C C   1 
ATOM 1894 O O   . PRO C 3 29  ? 121.893 144.704 89.520  1.00 67.52  ? 28  PRO C O   1 
ATOM 1895 C CB  . PRO C 3 29  ? 123.805 146.682 90.973  1.00 67.52  ? 28  PRO C CB  1 
ATOM 1896 C CG  . PRO C 3 29  ? 125.278 146.685 90.752  1.00 67.52  ? 28  PRO C CG  1 
ATOM 1897 C CD  . PRO C 3 29  ? 125.841 145.610 91.648  1.00 67.52  ? 28  PRO C CD  1 
ATOM 1898 N N   . THR C 3 30  ? 123.925 143.755 89.294  1.00 71.16  ? 29  THR C N   1 
ATOM 1899 C CA  . THR C 3 30  ? 123.574 143.140 88.017  1.00 71.16  ? 29  THR C CA  1 
ATOM 1900 C C   . THR C 3 30  ? 122.509 142.064 88.194  1.00 71.16  ? 29  THR C C   1 
ATOM 1901 O O   . THR C 3 30  ? 121.514 142.035 87.461  1.00 71.16  ? 29  THR C O   1 
ATOM 1902 C CB  . THR C 3 30  ? 124.822 142.555 87.354  1.00 71.16  ? 29  THR C CB  1 
ATOM 1903 O OG1 . THR C 3 30  ? 125.736 143.612 87.034  1.00 71.16  ? 29  THR C OG1 1 
ATOM 1904 C CG2 . THR C 3 30  ? 124.450 141.813 86.080  1.00 71.16  ? 29  THR C CG2 1 
ATOM 1905 N N   . ASN C 3 31  ? 122.698 141.170 89.167  1.00 68.41  ? 30  ASN C N   1 
ATOM 1906 C CA  . ASN C 3 31  ? 121.779 140.060 89.382  1.00 68.41  ? 30  ASN C CA  1 
ATOM 1907 C C   . ASN C 3 31  ? 121.357 139.906 90.839  1.00 68.41  ? 30  ASN C C   1 
ATOM 1908 O O   . ASN C 3 31  ? 120.734 138.896 91.185  1.00 68.41  ? 30  ASN C O   1 
ATOM 1909 C CB  . ASN C 3 31  ? 122.396 138.754 88.868  1.00 68.41  ? 30  ASN C CB  1 
ATOM 1910 C CG  . ASN C 3 31  ? 123.759 138.482 89.463  1.00 68.41  ? 30  ASN C CG  1 
ATOM 1911 O OD1 . ASN C 3 31  ? 123.875 138.055 90.608  1.00 68.41  ? 30  ASN C OD1 1 
ATOM 1912 N ND2 . ASN C 3 31  ? 124.804 138.728 88.683  1.00 68.41  ? 30  ASN C ND2 1 
ATOM 1913 N N   . GLY C 3 32  ? 121.676 140.872 91.696  1.00 62.49  ? 31  GLY C N   1 
ATOM 1914 C CA  . GLY C 3 32  ? 121.157 140.901 93.050  1.00 62.49  ? 31  GLY C CA  1 
ATOM 1915 C C   . GLY C 3 32  ? 121.581 139.770 93.965  1.00 62.49  ? 31  GLY C C   1 
ATOM 1916 O O   . GLY C 3 32  ? 120.741 139.193 94.661  1.00 62.49  ? 31  GLY C O   1 
ATOM 1917 N N   . VAL C 3 33  ? 122.870 139.441 93.983  1.00 54.45  ? 32  VAL C N   1 
ATOM 1918 C CA  . VAL C 3 33  ? 123.418 138.472 94.927  1.00 54.45  ? 32  VAL C CA  1 
ATOM 1919 C C   . VAL C 3 33  ? 124.144 139.225 96.032  1.00 54.45  ? 32  VAL C C   1 
ATOM 1920 O O   . VAL C 3 33  ? 124.944 140.129 95.761  1.00 54.45  ? 32  VAL C O   1 
ATOM 1921 C CB  . VAL C 3 33  ? 124.350 137.465 94.231  1.00 54.45  ? 32  VAL C CB  1 
ATOM 1922 C CG1 . VAL C 3 33  ? 123.553 136.551 93.323  1.00 54.45  ? 32  VAL C CG1 1 
ATOM 1923 C CG2 . VAL C 3 33  ? 125.429 138.183 93.437  1.00 54.45  ? 32  VAL C CG2 1 
ATOM 1924 N N   . ALA C 3 34  ? 123.851 138.869 97.278  1.00 46.07  ? 33  ALA C N   1 
ATOM 1925 C CA  . ALA C 3 34  ? 124.476 139.487 98.439  1.00 46.07  ? 33  ALA C CA  1 
ATOM 1926 C C   . ALA C 3 34  ? 125.605 138.588 98.921  1.00 46.07  ? 33  ALA C C   1 
ATOM 1927 O O   . ALA C 3 34  ? 125.373 137.425 99.264  1.00 46.07  ? 33  ALA C O   1 
ATOM 1928 C CB  . ALA C 3 34  ? 123.457 139.719 99.553  1.00 46.07  ? 33  ALA C CB  1 
ATOM 1929 N N   . SER C 3 35  ? 126.816 139.127 98.952  1.00 46.36  ? 34  SER C N   1 
ATOM 1930 C CA  . SER C 3 35  ? 128.003 138.354 99.276  1.00 46.36  ? 34  SER C CA  1 
ATOM 1931 C C   . SER C 3 35  ? 128.379 138.522 100.742 1.00 46.36  ? 34  SER C C   1 
ATOM 1932 O O   . SER C 3 35  ? 127.907 139.419 101.441 1.00 46.36  ? 34  SER C O   1 
ATOM 1933 C CB  . SER C 3 35  ? 129.174 138.770 98.381  1.00 46.36  ? 34  SER C CB  1 
ATOM 1934 O OG  . SER C 3 35  ? 128.825 138.684 97.012  1.00 46.36  ? 34  SER C OG  1 
ATOM 1935 N N   . LEU C 3 36  ? 129.249 137.627 101.199 1.00 46.81  ? 35  LEU C N   1 
ATOM 1936 C CA  . LEU C 3 36  ? 129.828 137.697 102.529 1.00 46.81  ? 35  LEU C CA  1 
ATOM 1937 C C   . LEU C 3 36  ? 131.268 137.221 102.428 1.00 46.81  ? 35  LEU C C   1 
ATOM 1938 O O   . LEU C 3 36  ? 131.640 136.514 101.488 1.00 46.81  ? 35  LEU C O   1 
ATOM 1939 C CB  . LEU C 3 36  ? 129.040 136.853 103.536 1.00 46.81  ? 35  LEU C CB  1 
ATOM 1940 C CG  . LEU C 3 36  ? 127.618 137.299 103.878 1.00 46.81  ? 35  LEU C CG  1 
ATOM 1941 C CD1 . LEU C 3 36  ? 126.862 136.179 104.565 1.00 46.81  ? 35  LEU C CD1 1 
ATOM 1942 C CD2 . LEU C 3 36  ? 127.649 138.528 104.759 1.00 46.81  ? 35  LEU C CD2 1 
ATOM 1943 N N   . SER C 3 37  ? 132.083 137.621 103.398 1.00 53.71  ? 36  SER C N   1 
ATOM 1944 C CA  . SER C 3 37  ? 133.501 137.299 103.341 1.00 53.71  ? 36  SER C CA  1 
ATOM 1945 C C   . SER C 3 37  ? 134.095 137.365 104.739 1.00 53.71  ? 36  SER C C   1 
ATOM 1946 O O   . SER C 3 37  ? 133.510 137.944 105.656 1.00 53.71  ? 36  SER C O   1 
ATOM 1947 C CB  . SER C 3 37  ? 134.247 138.241 102.390 1.00 53.71  ? 36  SER C CB  1 
ATOM 1948 O OG  . SER C 3 37  ? 134.050 137.862 101.040 1.00 53.71  ? 36  SER C OG  1 
ATOM 1949 N N   . GLN C 3 38  ? 135.264 136.749 104.886 1.00 56.13  ? 37  GLN C N   1 
ATOM 1950 C CA  . GLN C 3 38  ? 135.991 136.709 106.148 1.00 56.13  ? 37  GLN C CA  1 
ATOM 1951 C C   . GLN C 3 38  ? 137.284 137.505 106.021 1.00 56.13  ? 37  GLN C C   1 
ATOM 1952 O O   . GLN C 3 38  ? 138.001 137.379 105.025 1.00 56.13  ? 37  GLN C O   1 
ATOM 1953 C CB  . GLN C 3 38  ? 136.291 135.264 106.547 1.00 56.13  ? 37  GLN C CB  1 
ATOM 1954 C CG  . GLN C 3 38  ? 137.146 135.112 107.793 1.00 56.13  ? 37  GLN C CG  1 
ATOM 1955 C CD  . GLN C 3 38  ? 137.569 133.676 108.030 1.00 56.13  ? 37  GLN C CD  1 
ATOM 1956 O OE1 . GLN C 3 38  ? 137.329 132.803 107.196 1.00 56.13  ? 37  GLN C OE1 1 
ATOM 1957 N NE2 . GLN C 3 38  ? 138.207 133.423 109.167 1.00 56.13  ? 37  GLN C NE2 1 
ATOM 1958 N N   . ALA C 3 39  ? 137.588 138.315 107.032 1.00 64.21  ? 38  ALA C N   1 
ATOM 1959 C CA  . ALA C 3 39  ? 138.792 139.132 106.974 1.00 64.21  ? 38  ALA C CA  1 
ATOM 1960 C C   . ALA C 3 39  ? 140.036 138.263 107.117 1.00 64.21  ? 38  ALA C C   1 
ATOM 1961 O O   . ALA C 3 39  ? 140.556 138.089 108.224 1.00 64.21  ? 38  ALA C O   1 
ATOM 1962 C CB  . ALA C 3 39  ? 138.764 140.211 108.057 1.00 64.21  ? 38  ALA C CB  1 
ATOM 1963 N N   . GLY C 3 40  ? 140.514 137.713 106.004 1.00 70.38  ? 39  GLY C N   1 
ATOM 1964 C CA  . GLY C 3 40  ? 141.687 136.867 105.979 1.00 70.38  ? 39  GLY C CA  1 
ATOM 1965 C C   . GLY C 3 40  ? 142.955 137.523 105.478 1.00 70.38  ? 39  GLY C C   1 
ATOM 1966 O O   . GLY C 3 40  ? 143.933 136.816 105.212 1.00 70.38  ? 39  GLY C O   1 
ATOM 1967 N N   . ALA C 3 41  ? 142.962 138.847 105.321 1.00 72.57  ? 40  ALA C N   1 
ATOM 1968 C CA  . ALA C 3 41  ? 144.107 139.671 104.938 1.00 72.57  ? 40  ALA C CA  1 
ATOM 1969 C C   . ALA C 3 41  ? 144.583 139.432 103.508 1.00 72.57  ? 40  ALA C C   1 
ATOM 1970 O O   . ALA C 3 41  ? 145.474 140.154 103.045 1.00 72.57  ? 40  ALA C O   1 
ATOM 1971 C CB  . ALA C 3 41  ? 145.300 139.495 105.889 1.00 72.57  ? 40  ALA C CB  1 
ATOM 1972 N N   . VAL C 3 42  ? 144.026 138.460 102.793 1.00 67.09  ? 41  VAL C N   1 
ATOM 1973 C CA  . VAL C 3 42  ? 144.384 138.223 101.395 1.00 67.09  ? 41  VAL C CA  1 
ATOM 1974 C C   . VAL C 3 42  ? 143.108 137.964 100.602 1.00 67.09  ? 41  VAL C C   1 
ATOM 1975 O O   . VAL C 3 42  ? 142.359 137.031 100.923 1.00 67.09  ? 41  VAL C O   1 
ATOM 1976 C CB  . VAL C 3 42  ? 145.369 137.053 101.250 1.00 67.09  ? 41  VAL C CB  1 
ATOM 1977 C CG1 . VAL C 3 42  ? 145.504 136.661 99.790  1.00 67.09  ? 41  VAL C CG1 1 
ATOM 1978 C CG2 . VAL C 3 42  ? 146.725 137.418 101.829 1.00 67.09  ? 41  VAL C CG2 1 
ATOM 1979 N N   . PRO C 3 43  ? 142.818 138.761 99.572  1.00 61.68  ? 42  PRO C N   1 
ATOM 1980 C CA  . PRO C 3 43  ? 141.558 138.574 98.833  1.00 61.68  ? 42  PRO C CA  1 
ATOM 1981 C C   . PRO C 3 43  ? 141.436 137.230 98.134  1.00 61.68  ? 42  PRO C C   1 
ATOM 1982 O O   . PRO C 3 43  ? 140.316 136.724 97.990  1.00 61.68  ? 42  PRO C O   1 
ATOM 1983 C CB  . PRO C 3 43  ? 141.576 139.730 97.823  1.00 61.68  ? 42  PRO C CB  1 
ATOM 1984 C CG  . PRO C 3 43  ? 142.496 140.745 98.418  1.00 61.68  ? 42  PRO C CG  1 
ATOM 1985 C CD  . PRO C 3 43  ? 143.550 139.956 99.127  1.00 61.68  ? 42  PRO C CD  1 
ATOM 1986 N N   . ALA C 3 44  ? 142.543 136.635 97.687  1.00 62.20  ? 43  ALA C N   1 
ATOM 1987 C CA  . ALA C 3 44  ? 142.455 135.397 96.918  1.00 62.20  ? 43  ALA C CA  1 
ATOM 1988 C C   . ALA C 3 44  ? 142.146 134.190 97.793  1.00 62.20  ? 43  ALA C C   1 
ATOM 1989 O O   . ALA C 3 44  ? 141.386 133.308 97.377  1.00 62.20  ? 43  ALA C O   1 
ATOM 1990 C CB  . ALA C 3 44  ? 143.752 135.160 96.145  1.00 62.20  ? 43  ALA C CB  1 
ATOM 1991 N N   . LEU C 3 45  ? 142.712 134.130 98.994  1.00 66.19  ? 44  LEU C N   1 
ATOM 1992 C CA  . LEU C 3 45  ? 142.490 133.005 99.899  1.00 66.19  ? 44  LEU C CA  1 
ATOM 1993 C C   . LEU C 3 45  ? 141.324 133.340 100.826 1.00 66.19  ? 44  LEU C C   1 
ATOM 1994 O O   . LEU C 3 45  ? 141.479 133.587 102.021 1.00 66.19  ? 44  LEU C O   1 
ATOM 1995 C CB  . LEU C 3 45  ? 143.763 132.701 100.680 1.00 66.19  ? 44  LEU C CB  1 
ATOM 1996 C CG  . LEU C 3 45  ? 145.054 132.699 99.859  1.00 66.19  ? 44  LEU C CG  1 
ATOM 1997 C CD1 . LEU C 3 45  ? 146.267 132.620 100.771 1.00 66.19  ? 44  LEU C CD1 1 
ATOM 1998 C CD2 . LEU C 3 45  ? 145.056 131.568 98.850  1.00 66.19  ? 44  LEU C CD2 1 
ATOM 1999 N N   . GLU C 3 46  ? 140.130 133.339 100.238 1.00 61.06  ? 45  GLU C N   1 
ATOM 2000 C CA  . GLU C 3 46  ? 138.953 133.905 100.878 1.00 61.06  ? 45  GLU C CA  1 
ATOM 2001 C C   . GLU C 3 46  ? 137.802 132.910 100.898 1.00 61.06  ? 45  GLU C C   1 
ATOM 2002 O O   . GLU C 3 46  ? 137.425 132.362 99.860  1.00 61.06  ? 45  GLU C O   1 
ATOM 2003 C CB  . GLU C 3 46  ? 138.509 135.179 100.152 1.00 61.06  ? 45  GLU C CB  1 
ATOM 2004 C CG  . GLU C 3 46  ? 137.316 135.854 100.775 1.00 61.06  ? 45  GLU C CG  1 
ATOM 2005 C CD  . GLU C 3 46  ? 137.615 136.375 102.157 1.00 61.06  ? 45  GLU C CD  1 
ATOM 2006 O OE1 . GLU C 3 46  ? 138.796 136.663 102.445 1.00 61.06  ? 45  GLU C OE1 1 
ATOM 2007 O OE2 . GLU C 3 46  ? 136.668 136.472 102.959 1.00 61.06  ? 45  GLU C OE2 1 
ATOM 2008 N N   . LYS C 3 47  ? 137.233 132.705 102.084 1.00 55.14  ? 46  LYS C N   1 
ATOM 2009 C CA  . LYS C 3 47  ? 136.001 131.941 102.225 1.00 55.14  ? 46  LYS C CA  1 
ATOM 2010 C C   . LYS C 3 47  ? 134.809 132.871 102.050 1.00 55.14  ? 46  LYS C C   1 
ATOM 2011 O O   . LYS C 3 47  ? 134.626 133.807 102.833 1.00 55.14  ? 46  LYS C O   1 
ATOM 2012 C CB  . LYS C 3 47  ? 135.943 131.266 103.594 1.00 55.14  ? 46  LYS C CB  1 
ATOM 2013 C CG  . LYS C 3 47  ? 137.026 130.232 103.831 1.00 55.14  ? 46  LYS C CG  1 
ATOM 2014 C CD  . LYS C 3 47  ? 136.906 129.611 105.213 1.00 55.14  ? 46  LYS C CD  1 
ATOM 2015 C CE  . LYS C 3 47  ? 137.934 128.513 105.408 1.00 55.14  ? 46  LYS C CE  1 
ATOM 2016 N NZ  . LYS C 3 47  ? 139.319 129.053 105.395 1.00 55.14  ? 46  LYS C NZ  1 
ATOM 2017 N N   . ARG C 3 48  ? 133.994 132.614 101.030 1.00 47.79  ? 47  ARG C N   1 
ATOM 2018 C CA  . ARG C 3 48  ? 132.901 133.509 100.686 1.00 47.79  ? 47  ARG C CA  1 
ATOM 2019 C C   . ARG C 3 48  ? 131.585 132.750 100.609 1.00 47.79  ? 47  ARG C C   1 
ATOM 2020 O O   . ARG C 3 48  ? 131.546 131.571 100.249 1.00 47.79  ? 47  ARG C O   1 
ATOM 2021 C CB  . ARG C 3 48  ? 133.168 134.226 99.360  1.00 47.79  ? 47  ARG C CB  1 
ATOM 2022 C CG  . ARG C 3 48  ? 133.453 133.301 98.195  1.00 47.79  ? 47  ARG C CG  1 
ATOM 2023 C CD  . ARG C 3 48  ? 133.870 134.090 96.964  1.00 47.79  ? 47  ARG C CD  1 
ATOM 2024 N NE  . ARG C 3 48  ? 135.157 134.753 97.144  1.00 47.79  ? 47  ARG C NE  1 
ATOM 2025 C CZ  . ARG C 3 48  ? 135.308 136.038 97.438  1.00 47.79  ? 47  ARG C CZ  1 
ATOM 2026 N NH1 . ARG C 3 48  ? 134.267 136.837 97.605  1.00 47.79  ? 47  ARG C NH1 1 
ATOM 2027 N NH2 . ARG C 3 48  ? 136.536 136.532 97.570  1.00 47.79  ? 47  ARG C NH2 1 
ATOM 2028 N N   . VAL C 3 49  ? 130.505 133.445 100.961 1.00 39.75  ? 48  VAL C N   1 
ATOM 2029 C CA  . VAL C 3 49  ? 129.151 132.906 100.924 1.00 39.75  ? 48  VAL C CA  1 
ATOM 2030 C C   . VAL C 3 49  ? 128.255 133.909 100.213 1.00 39.75  ? 48  VAL C C   1 
ATOM 2031 O O   . VAL C 3 49  ? 128.317 135.112 100.490 1.00 39.75  ? 48  VAL C O   1 
ATOM 2032 C CB  . VAL C 3 49  ? 128.611 132.617 102.341 1.00 39.75  ? 48  VAL C CB  1 
ATOM 2033 C CG1 . VAL C 3 49  ? 127.238 131.971 102.263 1.00 39.75  ? 48  VAL C CG1 1 
ATOM 2034 C CG2 . VAL C 3 49  ? 129.577 131.740 103.118 1.00 39.75  ? 48  VAL C CG2 1 
ATOM 2035 N N   . THR C 3 50  ? 127.420 133.418 99.301  1.00 35.59  ? 49  THR C N   1 
ATOM 2036 C CA  . THR C 3 50  ? 126.491 134.262 98.563  1.00 35.59  ? 49  THR C CA  1 
ATOM 2037 C C   . THR C 3 50  ? 125.074 133.740 98.739  1.00 35.59  ? 49  THR C C   1 
ATOM 2038 O O   . THR C 3 50  ? 124.842 132.528 98.704  1.00 35.59  ? 49  THR C O   1 
ATOM 2039 C CB  . THR C 3 50  ? 126.834 134.316 97.071  1.00 35.59  ? 49  THR C CB  1 
ATOM 2040 O OG1 . THR C 3 50  ? 126.593 133.034 96.479  1.00 35.59  ? 49  THR C OG1 1 
ATOM 2041 C CG2 . THR C 3 50  ? 128.292 134.692 96.869  1.00 35.59  ? 49  THR C CG2 1 
ATOM 2042 N N   . VAL C 3 51  ? 124.130 134.659 98.925  1.00 37.69  ? 50  VAL C N   1 
ATOM 2043 C CA  . VAL C 3 51  ? 122.720 134.330 99.085  1.00 37.69  ? 50  VAL C CA  1 
ATOM 2044 C C   . VAL C 3 51  ? 121.897 135.285 98.232  1.00 37.69  ? 50  VAL C C   1 
ATOM 2045 O O   . VAL C 3 51  ? 122.199 136.481 98.156  1.00 37.69  ? 50  VAL C O   1 
ATOM 2046 C CB  . VAL C 3 51  ? 122.287 134.390 100.567 1.00 37.69  ? 50  VAL C CB  1 
ATOM 2047 C CG1 . VAL C 3 51  ? 122.523 135.775 101.147 1.00 37.69  ? 50  VAL C CG1 1 
ATOM 2048 C CG2 . VAL C 3 51  ? 120.830 133.987 100.720 1.00 37.69  ? 50  VAL C CG2 1 
ATOM 2049 N N   . SER C 3 52  ? 120.871 134.754 97.570  1.00 40.09  ? 51  SER C N   1 
ATOM 2050 C CA  . SER C 3 52  ? 120.014 135.577 96.730  1.00 40.09  ? 51  SER C CA  1 
ATOM 2051 C C   . SER C 3 52  ? 118.667 134.894 96.559  1.00 40.09  ? 51  SER C C   1 
ATOM 2052 O O   . SER C 3 52  ? 118.593 133.665 96.501  1.00 40.09  ? 51  SER C O   1 
ATOM 2053 C CB  . SER C 3 52  ? 120.650 135.828 95.360  1.00 40.09  ? 51  SER C CB  1 
ATOM 2054 O OG  . SER C 3 52  ? 120.686 134.640 94.591  1.00 40.09  ? 51  SER C OG  1 
ATOM 2055 N N   . VAL C 3 53  ? 117.609 135.699 96.474  1.00 44.93  ? 52  VAL C N   1 
ATOM 2056 C CA  . VAL C 3 53  ? 116.271 135.207 96.184  1.00 44.93  ? 52  VAL C CA  1 
ATOM 2057 C C   . VAL C 3 53  ? 115.774 135.899 94.922  1.00 44.93  ? 52  VAL C C   1 
ATOM 2058 O O   . VAL C 3 53  ? 116.224 136.989 94.560  1.00 44.93  ? 52  VAL C O   1 
ATOM 2059 C CB  . VAL C 3 53  ? 115.290 135.430 97.352  1.00 44.93  ? 52  VAL C CB  1 
ATOM 2060 C CG1 . VAL C 3 53  ? 115.898 134.949 98.658  1.00 44.93  ? 52  VAL C CG1 1 
ATOM 2061 C CG2 . VAL C 3 53  ? 114.892 136.887 97.443  1.00 44.93  ? 52  VAL C CG2 1 
ATOM 2062 N N   . SER C 3 54  ? 114.840 135.244 94.244  1.00 55.65  ? 53  SER C N   1 
ATOM 2063 C CA  . SER C 3 54  ? 114.324 135.710 92.967  1.00 55.65  ? 53  SER C CA  1 
ATOM 2064 C C   . SER C 3 54  ? 112.856 136.103 93.100  1.00 55.65  ? 53  SER C C   1 
ATOM 2065 O O   . SER C 3 54  ? 112.262 136.046 94.180  1.00 55.65  ? 53  SER C O   1 
ATOM 2066 C CB  . SER C 3 54  ? 114.508 134.637 91.892  1.00 55.65  ? 53  SER C CB  1 
ATOM 2067 O OG  . SER C 3 54  ? 113.712 134.916 90.754  1.00 55.65  ? 53  SER C OG  1 
ATOM 2068 N N   . GLN C 3 55  ? 112.276 136.512 91.977  1.00 66.18  ? 54  GLN C N   1 
ATOM 2069 C CA  . GLN C 3 55  ? 110.883 136.918 91.881  1.00 66.18  ? 54  GLN C CA  1 
ATOM 2070 C C   . GLN C 3 55  ? 110.269 136.270 90.649  1.00 66.18  ? 54  GLN C C   1 
ATOM 2071 O O   . GLN C 3 55  ? 110.976 136.000 89.672  1.00 66.18  ? 54  GLN C O   1 
ATOM 2072 C CB  . GLN C 3 55  ? 110.745 138.447 91.789  1.00 66.18  ? 54  GLN C CB  1 
ATOM 2073 C CG  . GLN C 3 55  ? 111.506 139.215 92.861  1.00 66.18  ? 54  GLN C CG  1 
ATOM 2074 C CD  . GLN C 3 55  ? 110.639 139.577 94.050  1.00 66.18  ? 54  GLN C CD  1 
ATOM 2075 O OE1 . GLN C 3 55  ? 109.527 140.080 93.892  1.00 66.18  ? 54  GLN C OE1 1 
ATOM 2076 N NE2 . GLN C 3 55  ? 111.144 139.321 95.250  1.00 66.18  ? 54  GLN C NE2 1 
ATOM 2077 N N   . PRO C 3 56  ? 108.952 136.007 90.665  1.00 66.02  ? 55  PRO C N   1 
ATOM 2078 C CA  . PRO C 3 56  ? 108.299 135.397 89.502  1.00 66.02  ? 55  PRO C CA  1 
ATOM 2079 C C   . PRO C 3 56  ? 108.200 136.353 88.317  1.00 66.02  ? 55  PRO C C   1 
ATOM 2080 O O   . PRO C 3 56  ? 108.349 137.559 88.510  1.00 66.02  ? 55  PRO C O   1 
ATOM 2081 C CB  . PRO C 3 56  ? 106.907 135.040 90.029  1.00 66.02  ? 55  PRO C CB  1 
ATOM 2082 C CG  . PRO C 3 56  ? 106.670 136.000 91.134  1.00 66.02  ? 55  PRO C CG  1 
ATOM 2083 C CD  . PRO C 3 56  ? 108.008 136.228 91.773  1.00 66.02  ? 55  PRO C CD  1 
ATOM 2084 N N   . ASN C 3 62  ? 106.982 131.192 90.762  1.00 57.48  ? 61  ASN C N   1 
ATOM 2085 C CA  . ASN C 3 62  ? 107.876 130.222 91.381  1.00 57.48  ? 61  ASN C CA  1 
ATOM 2086 C C   . ASN C 3 62  ? 109.109 130.899 91.963  1.00 57.48  ? 61  ASN C C   1 
ATOM 2087 O O   . ASN C 3 62  ? 110.096 131.116 91.263  1.00 57.48  ? 61  ASN C O   1 
ATOM 2088 C CB  . ASN C 3 62  ? 108.296 129.158 90.368  1.00 57.48  ? 61  ASN C CB  1 
ATOM 2089 C CG  . ASN C 3 62  ? 107.128 128.334 89.874  1.00 57.48  ? 61  ASN C CG  1 
ATOM 2090 O OD1 . ASN C 3 62  ? 106.772 128.383 88.697  1.00 57.48  ? 61  ASN C OD1 1 
ATOM 2091 N ND2 . ASN C 3 62  ? 106.523 127.569 90.774  1.00 57.48  ? 61  ASN C ND2 1 
ATOM 2092 N N   . TYR C 3 63  ? 109.044 131.235 93.248  1.00 50.91  ? 62  TYR C N   1 
ATOM 2093 C CA  . TYR C 3 63  ? 110.178 131.856 93.916  1.00 50.91  ? 62  TYR C CA  1 
ATOM 2094 C C   . TYR C 3 63  ? 111.333 130.870 94.033  1.00 50.91  ? 62  TYR C C   1 
ATOM 2095 O O   . TYR C 3 63  ? 111.131 129.676 94.265  1.00 50.91  ? 62  TYR C O   1 
ATOM 2096 C CB  . TYR C 3 63  ? 109.768 132.353 95.300  1.00 50.91  ? 62  TYR C CB  1 
ATOM 2097 C CG  . TYR C 3 63  ? 108.781 133.494 95.267  1.00 50.91  ? 62  TYR C CG  1 
ATOM 2098 C CD1 . TYR C 3 63  ? 107.415 133.255 95.230  1.00 50.91  ? 62  TYR C CD1 1 
ATOM 2099 C CD2 . TYR C 3 63  ? 109.214 134.811 95.273  1.00 50.91  ? 62  TYR C CD2 1 
ATOM 2100 C CE1 . TYR C 3 63  ? 106.510 134.294 95.200  1.00 50.91  ? 62  TYR C CE1 1 
ATOM 2101 C CE2 . TYR C 3 63  ? 108.316 135.857 95.244  1.00 50.91  ? 62  TYR C CE2 1 
ATOM 2102 C CZ  . TYR C 3 63  ? 106.966 135.593 95.206  1.00 50.91  ? 62  TYR C CZ  1 
ATOM 2103 O OH  . TYR C 3 63  ? 106.066 136.633 95.177  1.00 50.91  ? 62  TYR C OH  1 
ATOM 2104 N N   . LYS C 3 64  ? 112.552 131.379 93.871  1.00 40.57  ? 63  LYS C N   1 
ATOM 2105 C CA  . LYS C 3 64  ? 113.755 130.560 93.919  1.00 40.57  ? 63  LYS C CA  1 
ATOM 2106 C C   . LYS C 3 64  ? 114.749 131.177 94.890  1.00 40.57  ? 63  LYS C C   1 
ATOM 2107 O O   . LYS C 3 64  ? 115.020 132.380 94.824  1.00 40.57  ? 63  LYS C O   1 
ATOM 2108 C CB  . LYS C 3 64  ? 114.384 130.426 92.530  1.00 40.57  ? 63  LYS C CB  1 
ATOM 2109 C CG  . LYS C 3 64  ? 115.426 129.328 92.426  1.00 40.57  ? 63  LYS C CG  1 
ATOM 2110 C CD  . LYS C 3 64  ? 115.697 128.951 90.978  1.00 40.57  ? 63  LYS C CD  1 
ATOM 2111 C CE  . LYS C 3 64  ? 114.421 128.945 90.150  1.00 40.57  ? 63  LYS C CE  1 
ATOM 2112 N NZ  . LYS C 3 64  ? 113.491 127.859 90.565  1.00 40.57  ? 63  LYS C NZ  1 
ATOM 2113 N N   . VAL C 3 65  ? 115.290 130.354 95.785  1.00 35.38  ? 64  VAL C N   1 
ATOM 2114 C CA  . VAL C 3 65  ? 116.277 130.778 96.769  1.00 35.38  ? 64  VAL C CA  1 
ATOM 2115 C C   . VAL C 3 65  ? 117.539 129.956 96.557  1.00 35.38  ? 64  VAL C C   1 
ATOM 2116 O O   . VAL C 3 65  ? 117.474 128.725 96.469  1.00 35.38  ? 64  VAL C O   1 
ATOM 2117 C CB  . VAL C 3 65  ? 115.755 130.612 98.207  1.00 35.38  ? 64  VAL C CB  1 
ATOM 2118 C CG1 . VAL C 3 65  ? 116.788 131.105 99.204  1.00 35.38  ? 64  VAL C CG1 1 
ATOM 2119 C CG2 . VAL C 3 65  ? 114.442 131.353 98.382  1.00 35.38  ? 64  VAL C CG2 1 
ATOM 2120 N N   . GLN C 3 66  ? 118.682 130.632 96.477  1.00 31.49  ? 65  GLN C N   1 
ATOM 2121 C CA  . GLN C 3 66  ? 119.952 129.983 96.187  1.00 31.49  ? 65  GLN C CA  1 
ATOM 2122 C C   . GLN C 3 66  ? 121.001 130.408 97.203  1.00 31.49  ? 65  GLN C C   1 
ATOM 2123 O O   . GLN C 3 66  ? 121.080 131.582 97.572  1.00 31.49  ? 65  GLN C O   1 
ATOM 2124 C CB  . GLN C 3 66  ? 120.431 130.322 94.774  1.00 31.49  ? 65  GLN C CB  1 
ATOM 2125 C CG  . GLN C 3 66  ? 121.394 129.310 94.189  1.00 31.49  ? 65  GLN C CG  1 
ATOM 2126 C CD  . GLN C 3 66  ? 121.260 129.188 92.687  1.00 31.49  ? 65  GLN C CD  1 
ATOM 2127 O OE1 . GLN C 3 66  ? 120.389 129.807 92.079  1.00 31.49  ? 65  GLN C OE1 1 
ATOM 2128 N NE2 . GLN C 3 66  ? 122.127 128.388 92.079  1.00 31.49  ? 65  GLN C NE2 1 
ATOM 2129 N N   . VAL C 3 67  ? 121.801 129.445 97.654  1.00 33.63  ? 66  VAL C N   1 
ATOM 2130 C CA  . VAL C 3 67  ? 122.893 129.691 98.589  1.00 33.63  ? 66  VAL C CA  1 
ATOM 2131 C C   . VAL C 3 67  ? 124.110 128.913 98.113  1.00 33.63  ? 66  VAL C C   1 
ATOM 2132 O O   . VAL C 3 67  ? 124.020 127.707 97.859  1.00 33.63  ? 66  VAL C O   1 
ATOM 2133 C CB  . VAL C 3 67  ? 122.519 129.283 100.027 1.00 33.63  ? 66  VAL C CB  1 
ATOM 2134 C CG1 . VAL C 3 67  ? 123.760 129.200 100.897 1.00 33.63  ? 66  VAL C CG1 1 
ATOM 2135 C CG2 . VAL C 3 67  ? 121.521 130.263 100.614 1.00 33.63  ? 66  VAL C CG2 1 
ATOM 2136 N N   . LYS C 3 68  ? 125.248 129.594 97.995  1.00 33.82  ? 67  LYS C N   1 
ATOM 2137 C CA  . LYS C 3 68  ? 126.481 128.977 97.528  1.00 33.82  ? 67  LYS C CA  1 
ATOM 2138 C C   . LYS C 3 68  ? 127.594 129.216 98.536  1.00 33.82  ? 67  LYS C C   1 
ATOM 2139 O O   . LYS C 3 68  ? 127.718 130.313 99.088  1.00 33.82  ? 67  LYS C O   1 
ATOM 2140 C CB  . LYS C 3 68  ? 126.887 129.522 96.155  1.00 33.82  ? 67  LYS C CB  1 
ATOM 2141 C CG  . LYS C 3 68  ? 125.895 129.200 95.052  1.00 33.82  ? 67  LYS C CG  1 
ATOM 2142 C CD  . LYS C 3 68  ? 126.564 129.187 93.689  1.00 33.82  ? 67  LYS C CD  1 
ATOM 2143 C CE  . LYS C 3 68  ? 126.746 130.594 93.149  1.00 33.82  ? 67  LYS C CE  1 
ATOM 2144 N NZ  . LYS C 3 68  ? 125.547 131.442 93.391  1.00 33.82  ? 67  LYS C NZ  1 
ATOM 2145 N N   . ILE C 3 69  ? 128.403 128.186 98.770  1.00 39.19  ? 68  ILE C N   1 
ATOM 2146 C CA  . ILE C 3 69  ? 129.513 128.243 99.713  1.00 39.19  ? 68  ILE C CA  1 
ATOM 2147 C C   . ILE C 3 69  ? 130.785 127.840 98.984  1.00 39.19  ? 68  ILE C C   1 
ATOM 2148 O O   . ILE C 3 69  ? 130.799 126.852 98.243  1.00 39.19  ? 68  ILE C O   1 
ATOM 2149 C CB  . ILE C 3 69  ? 129.270 127.334 100.935 1.00 39.19  ? 68  ILE C CB  1 
ATOM 2150 C CG1 . ILE C 3 69  ? 128.171 127.919 101.821 1.00 39.19  ? 68  ILE C CG1 1 
ATOM 2151 C CG2 . ILE C 3 69  ? 130.548 127.151 101.734 1.00 39.19  ? 68  ILE C CG2 1 
ATOM 2152 C CD1 . ILE C 3 69  ? 127.903 127.113 103.068 1.00 39.19  ? 68  ILE C CD1 1 
ATOM 2153 N N   . GLN C 3 70  ? 131.852 128.609 99.188  1.00 48.58  ? 69  GLN C N   1 
ATOM 2154 C CA  . GLN C 3 70  ? 133.120 128.392 98.506  1.00 48.58  ? 69  GLN C CA  1 
ATOM 2155 C C   . GLN C 3 70  ? 134.250 128.410 99.524  1.00 48.58  ? 69  GLN C C   1 
ATOM 2156 O O   . GLN C 3 70  ? 134.336 129.334 100.338 1.00 48.58  ? 69  GLN C O   1 
ATOM 2157 C CB  . GLN C 3 70  ? 133.346 129.463 97.439  1.00 48.58  ? 69  GLN C CB  1 
ATOM 2158 C CG  . GLN C 3 70  ? 134.603 129.281 96.628  1.00 48.58  ? 69  GLN C CG  1 
ATOM 2159 C CD  . GLN C 3 70  ? 134.414 129.689 95.183  1.00 48.58  ? 69  GLN C CD  1 
ATOM 2160 O OE1 . GLN C 3 70  ? 133.463 129.266 94.527  1.00 48.58  ? 69  GLN C OE1 1 
ATOM 2161 N NE2 . GLN C 3 70  ? 135.318 130.521 94.680  1.00 48.58  ? 69  GLN C NE2 1 
ATOM 2162 N N   . ASN C 3 71  ? 135.113 127.402 99.472  1.00 52.52  ? 70  ASN C N   1 
ATOM 2163 C CA  . ASN C 3 71  ? 136.218 127.263 100.421 1.00 52.52  ? 70  ASN C CA  1 
ATOM 2164 C C   . ASN C 3 71  ? 137.508 126.949 99.677  1.00 52.52  ? 70  ASN C C   1 
ATOM 2165 O O   . ASN C 3 71  ? 137.669 125.816 99.177  1.00 52.52  ? 70  ASN C O   1 
ATOM 2166 C CB  . ASN C 3 71  ? 135.919 126.175 101.447 1.00 52.52  ? 70  ASN C CB  1 
ATOM 2167 C CG  . ASN C 3 71  ? 135.191 126.705 102.662 1.00 52.52  ? 70  ASN C CG  1 
ATOM 2168 O OD1 . ASN C 3 71  ? 134.756 127.854 102.687 1.00 52.52  ? 70  ASN C OD1 1 
ATOM 2169 N ND2 . ASN C 3 71  ? 135.053 125.866 103.681 1.00 52.52  ? 70  ASN C ND2 1 
ATOM 2170 N N   . PRO C 3 72  ? 138.439 127.893 99.574  1.00 57.00  ? 71  PRO C N   1 
ATOM 2171 C CA  . PRO C 3 72  ? 139.727 127.612 98.937  1.00 57.00  ? 71  PRO C CA  1 
ATOM 2172 C C   . PRO C 3 72  ? 140.784 127.171 99.936  1.00 57.00  ? 71  PRO C C   1 
ATOM 2173 O O   . PRO C 3 72  ? 140.788 127.566 101.103 1.00 57.00  ? 71  PRO C O   1 
ATOM 2174 C CB  . PRO C 3 72  ? 140.094 128.966 98.318  1.00 57.00  ? 71  PRO C CB  1 
ATOM 2175 C CG  . PRO C 3 72  ? 139.517 129.955 99.274  1.00 57.00  ? 71  PRO C CG  1 
ATOM 2176 C CD  . PRO C 3 72  ? 138.293 129.320 99.903  1.00 57.00  ? 71  PRO C CD  1 
ATOM 2177 N N   . THR C 3 73  ? 141.696 126.334 99.451  1.00 68.09  ? 72  THR C N   1 
ATOM 2178 C CA  . THR C 3 73  ? 142.802 125.818 100.247 1.00 68.09  ? 72  THR C CA  1 
ATOM 2179 C C   . THR C 3 73  ? 144.111 126.394 99.726  1.00 68.09  ? 72  THR C C   1 
ATOM 2180 O O   . THR C 3 73  ? 144.391 126.324 98.524  1.00 68.09  ? 72  THR C O   1 
ATOM 2181 C CB  . THR C 3 73  ? 142.846 124.289 100.206 1.00 68.09  ? 72  THR C CB  1 
ATOM 2182 O OG1 . THR C 3 73  ? 141.634 123.760 100.755 1.00 68.09  ? 72  THR C OG1 1 
ATOM 2183 C CG2 . THR C 3 73  ? 144.029 123.770 101.008 1.00 68.09  ? 72  THR C CG2 1 
ATOM 2184 N N   . ALA C 3 74  ? 144.908 126.958 100.629 1.00 82.24  ? 73  ALA C N   1 
ATOM 2185 C CA  . ALA C 3 74  ? 146.153 127.614 100.259 1.00 82.24  ? 73  ALA C CA  1 
ATOM 2186 C C   . ALA C 3 74  ? 147.344 126.712 100.548 1.00 82.24  ? 73  ALA C C   1 
ATOM 2187 O O   . ALA C 3 74  ? 147.437 126.106 101.619 1.00 82.24  ? 73  ALA C O   1 
ATOM 2188 C CB  . ALA C 3 74  ? 146.309 128.933 101.014 1.00 82.24  ? 73  ALA C CB  1 
ATOM 2189 N N   . CYS C 3 75  ? 148.258 126.630 99.583  1.00 105.54 ? 74  CYS C N   1 
ATOM 2190 C CA  . CYS C 3 75  ? 149.496 125.884 99.746  1.00 105.54 ? 74  CYS C CA  1 
ATOM 2191 C C   . CYS C 3 75  ? 150.660 126.754 99.299  1.00 105.54 ? 74  CYS C C   1 
ATOM 2192 O O   . CYS C 3 75  ? 150.544 127.510 98.330  1.00 105.54 ? 74  CYS C O   1 
ATOM 2193 C CB  . CYS C 3 75  ? 149.476 124.570 98.952  1.00 105.54 ? 74  CYS C CB  1 
ATOM 2194 S SG  . CYS C 3 75  ? 149.827 124.734 97.185  1.00 105.54 ? 74  CYS C SG  1 
ATOM 2195 N N   . THR C 3 76  ? 151.774 126.654 100.018 1.00 124.85 ? 75  THR C N   1 
ATOM 2196 C CA  . THR C 3 76  ? 152.966 127.427 99.683  1.00 124.85 ? 75  THR C CA  1 
ATOM 2197 C C   . THR C 3 76  ? 153.605 126.846 98.429  1.00 124.85 ? 75  THR C C   1 
ATOM 2198 O O   . THR C 3 76  ? 154.162 125.743 98.460  1.00 124.85 ? 75  THR C O   1 
ATOM 2199 C CB  . THR C 3 76  ? 153.949 127.420 100.850 1.00 124.85 ? 75  THR C CB  1 
ATOM 2200 O OG1 . THR C 3 76  ? 153.305 127.939 102.021 1.00 124.85 ? 75  THR C OG1 1 
ATOM 2201 C CG2 . THR C 3 76  ? 155.162 128.277 100.525 1.00 124.85 ? 75  THR C CG2 1 
ATOM 2202 N N   . ALA C 3 77  ? 153.523 127.582 97.323  1.00 133.61 ? 76  ALA C N   1 
ATOM 2203 C CA  . ALA C 3 77  ? 154.068 127.100 96.062  1.00 133.61 ? 76  ALA C CA  1 
ATOM 2204 C C   . ALA C 3 77  ? 155.583 126.975 96.144  1.00 133.61 ? 76  ALA C C   1 
ATOM 2205 O O   . ALA C 3 77  ? 156.257 127.774 96.799  1.00 133.61 ? 76  ALA C O   1 
ATOM 2206 C CB  . ALA C 3 77  ? 153.677 128.041 94.922  1.00 133.61 ? 76  ALA C CB  1 
ATOM 2207 N N   . ASN C 3 78  ? 156.118 125.958 95.473  1.00 141.95 ? 77  ASN C N   1 
ATOM 2208 C CA  . ASN C 3 78  ? 157.555 125.727 95.460  1.00 141.95 ? 77  ASN C CA  1 
ATOM 2209 C C   . ASN C 3 78  ? 158.229 126.703 94.504  1.00 141.95 ? 77  ASN C C   1 
ATOM 2210 O O   . ASN C 3 78  ? 157.775 126.890 93.371  1.00 141.95 ? 77  ASN C O   1 
ATOM 2211 C CB  . ASN C 3 78  ? 157.860 124.286 95.054  1.00 141.95 ? 77  ASN C CB  1 
ATOM 2212 C CG  . ASN C 3 78  ? 159.188 123.797 95.594  1.00 141.95 ? 77  ASN C CG  1 
ATOM 2213 O OD1 . ASN C 3 78  ? 160.105 124.584 95.826  1.00 141.95 ? 77  ASN C OD1 1 
ATOM 2214 N ND2 . ASN C 3 78  ? 159.298 122.489 95.799  1.00 141.95 ? 77  ASN C ND2 1 
ATOM 2215 N N   . GLY C 3 79  ? 159.314 127.319 94.961  1.00 140.60 ? 78  GLY C N   1 
ATOM 2216 C CA  . GLY C 3 79  ? 160.017 128.300 94.152  1.00 140.60 ? 78  GLY C CA  1 
ATOM 2217 C C   . GLY C 3 79  ? 159.226 129.562 93.886  1.00 140.60 ? 78  GLY C C   1 
ATOM 2218 O O   . GLY C 3 79  ? 159.284 130.103 92.775  1.00 140.60 ? 78  GLY C O   1 
ATOM 2219 N N   . SER C 3 80  ? 158.488 130.047 94.881  1.00 133.85 ? 79  SER C N   1 
ATOM 2220 C CA  . SER C 3 80  ? 157.695 131.259 94.733  1.00 133.85 ? 79  SER C CA  1 
ATOM 2221 C C   . SER C 3 80  ? 157.471 131.856 96.115  1.00 133.85 ? 79  SER C C   1 
ATOM 2222 O O   . SER C 3 80  ? 157.670 131.198 97.138  1.00 133.85 ? 79  SER C O   1 
ATOM 2223 C CB  . SER C 3 80  ? 156.363 130.977 94.031  1.00 133.85 ? 79  SER C CB  1 
ATOM 2224 O OG  . SER C 3 80  ? 155.612 132.166 93.866  1.00 133.85 ? 79  SER C OG  1 
ATOM 2225 N N   . CYS C 3 81  ? 157.053 133.122 96.131  1.00 125.90 ? 80  CYS C N   1 
ATOM 2226 C CA  . CYS C 3 81  ? 156.832 133.852 97.375  1.00 125.90 ? 80  CYS C CA  1 
ATOM 2227 C C   . CYS C 3 81  ? 155.358 133.888 97.765  1.00 125.90 ? 80  CYS C C   1 
ATOM 2228 O O   . CYS C 3 81  ? 154.992 133.454 98.861  1.00 125.90 ? 80  CYS C O   1 
ATOM 2229 C CB  . CYS C 3 81  ? 157.390 135.276 97.252  1.00 125.90 ? 80  CYS C CB  1 
ATOM 2230 S SG  . CYS C 3 81  ? 159.165 135.352 96.914  1.00 125.90 ? 80  CYS C SG  1 
ATOM 2231 N N   . ASP C 3 82  ? 154.503 134.403 96.886  1.00 114.17 ? 81  ASP C N   1 
ATOM 2232 C CA  . ASP C 3 82  ? 153.087 134.488 97.201  1.00 114.17 ? 81  ASP C CA  1 
ATOM 2233 C C   . ASP C 3 82  ? 152.431 133.108 97.144  1.00 114.17 ? 81  ASP C C   1 
ATOM 2234 O O   . ASP C 3 82  ? 152.823 132.254 96.344  1.00 114.17 ? 81  ASP C O   1 
ATOM 2235 C CB  . ASP C 3 82  ? 152.381 135.458 96.253  1.00 114.17 ? 81  ASP C CB  1 
ATOM 2236 C CG  . ASP C 3 82  ? 152.719 135.215 94.789  1.00 114.17 ? 81  ASP C CG  1 
ATOM 2237 O OD1 . ASP C 3 82  ? 152.980 134.060 94.398  1.00 114.17 ? 81  ASP C OD1 1 
ATOM 2238 O OD2 . ASP C 3 82  ? 152.720 136.198 94.018  1.00 114.17 ? 81  ASP C OD2 1 
ATOM 2239 N N   . PRO C 3 83  ? 151.448 132.856 98.002  1.00 98.41  ? 82  PRO C N   1 
ATOM 2240 C CA  . PRO C 3 83  ? 150.733 131.578 97.948  1.00 98.41  ? 82  PRO C CA  1 
ATOM 2241 C C   . PRO C 3 83  ? 149.774 131.528 96.769  1.00 98.41  ? 82  PRO C C   1 
ATOM 2242 O O   . PRO C 3 83  ? 149.409 132.546 96.179  1.00 98.41  ? 82  PRO C O   1 
ATOM 2243 C CB  . PRO C 3 83  ? 149.977 131.536 99.279  1.00 98.41  ? 82  PRO C CB  1 
ATOM 2244 C CG  . PRO C 3 83  ? 149.795 132.967 99.644  1.00 98.41  ? 82  PRO C CG  1 
ATOM 2245 C CD  . PRO C 3 83  ? 151.010 133.689 99.135  1.00 98.41  ? 82  PRO C CD  1 
ATOM 2246 N N   . SER C 3 84  ? 149.369 130.307 96.427  1.00 90.10  ? 83  SER C N   1 
ATOM 2247 C CA  . SER C 3 84  ? 148.422 130.080 95.347  1.00 90.10  ? 83  SER C CA  1 
ATOM 2248 C C   . SER C 3 84  ? 147.406 129.036 95.782  1.00 90.10  ? 83  SER C C   1 
ATOM 2249 O O   . SER C 3 84  ? 147.691 128.185 96.629  1.00 90.10  ? 83  SER C O   1 
ATOM 2250 C CB  . SER C 3 84  ? 149.129 129.627 94.063  1.00 90.10  ? 83  SER C CB  1 
ATOM 2251 O OG  . SER C 3 84  ? 148.196 129.402 93.021  1.00 90.10  ? 83  SER C OG  1 
ATOM 2252 N N   . VAL C 3 85  ? 146.216 129.108 95.194  1.00 80.35  ? 84  VAL C N   1 
ATOM 2253 C CA  . VAL C 3 85  ? 145.148 128.166 95.513  1.00 80.35  ? 84  VAL C CA  1 
ATOM 2254 C C   . VAL C 3 85  ? 145.391 126.859 94.770  1.00 80.35  ? 84  VAL C C   1 
ATOM 2255 O O   . VAL C 3 85  ? 145.714 126.855 93.576  1.00 80.35  ? 84  VAL C O   1 
ATOM 2256 C CB  . VAL C 3 85  ? 143.772 128.763 95.174  1.00 80.35  ? 84  VAL C CB  1 
ATOM 2257 C CG1 . VAL C 3 85  ? 143.495 129.970 96.046  1.00 80.35  ? 84  VAL C CG1 1 
ATOM 2258 C CG2 . VAL C 3 85  ? 143.701 129.159 93.707  1.00 80.35  ? 84  VAL C CG2 1 
ATOM 2259 N N   . THR C 3 86  ? 145.260 125.742 95.485  1.00 76.58  ? 85  THR C N   1 
ATOM 2260 C CA  . THR C 3 86  ? 145.447 124.417 94.902  1.00 76.58  ? 85  THR C CA  1 
ATOM 2261 C C   . THR C 3 86  ? 144.116 123.734 94.604  1.00 76.58  ? 85  THR C C   1 
ATOM 2262 O O   . THR C 3 86  ? 143.853 123.349 93.462  1.00 76.58  ? 85  THR C O   1 
ATOM 2263 C CB  . THR C 3 86  ? 146.295 123.545 95.836  1.00 76.58  ? 85  THR C CB  1 
ATOM 2264 O OG1 . THR C 3 86  ? 147.562 124.175 96.060  1.00 76.58  ? 85  THR C OG1 1 
ATOM 2265 C CG2 . THR C 3 86  ? 146.521 122.174 95.223  1.00 76.58  ? 85  THR C CG2 1 
ATOM 2266 N N   . ARG C 3 87  ? 143.267 123.580 95.617  1.00 67.27  ? 86  ARG C N   1 
ATOM 2267 C CA  . ARG C 3 87  ? 141.989 122.902 95.473  1.00 67.27  ? 86  ARG C CA  1 
ATOM 2268 C C   . ARG C 3 87  ? 140.900 123.716 96.156  1.00 67.27  ? 86  ARG C C   1 
ATOM 2269 O O   . ARG C 3 87  ? 141.164 124.516 97.057  1.00 67.27  ? 86  ARG C O   1 
ATOM 2270 C CB  . ARG C 3 87  ? 142.035 121.484 96.055  1.00 67.27  ? 86  ARG C CB  1 
ATOM 2271 C CG  . ARG C 3 87  ? 142.719 121.389 97.405  1.00 67.27  ? 86  ARG C CG  1 
ATOM 2272 C CD  . ARG C 3 87  ? 142.811 119.948 97.872  1.00 67.27  ? 86  ARG C CD  1 
ATOM 2273 N NE  . ARG C 3 87  ? 143.066 119.855 99.304  1.00 67.27  ? 86  ARG C NE  1 
ATOM 2274 C CZ  . ARG C 3 87  ? 144.273 119.835 99.850  1.00 67.27  ? 86  ARG C CZ  1 
ATOM 2275 N NH1 . ARG C 3 87  ? 145.367 119.900 99.109  1.00 67.27  ? 86  ARG C NH1 1 
ATOM 2276 N NH2 . ARG C 3 87  ? 144.387 119.746 101.172 1.00 67.27  ? 86  ARG C NH2 1 
ATOM 2277 N N   . GLN C 3 88  ? 139.664 123.499 95.713  1.00 55.29  ? 87  GLN C N   1 
ATOM 2278 C CA  . GLN C 3 88  ? 138.523 124.266 96.190  1.00 55.29  ? 87  GLN C CA  1 
ATOM 2279 C C   . GLN C 3 88  ? 137.367 123.325 96.491  1.00 55.29  ? 87  GLN C C   1 
ATOM 2280 O O   . GLN C 3 88  ? 137.165 122.334 95.784  1.00 55.29  ? 87  GLN C O   1 
ATOM 2281 C CB  . GLN C 3 88  ? 138.102 125.311 95.152  1.00 55.29  ? 87  GLN C CB  1 
ATOM 2282 C CG  . GLN C 3 88  ? 139.007 126.527 95.113  1.00 55.29  ? 87  GLN C CG  1 
ATOM 2283 C CD  . GLN C 3 88  ? 138.318 127.750 94.552  1.00 55.29  ? 87  GLN C CD  1 
ATOM 2284 O OE1 . GLN C 3 88  ? 137.311 128.210 95.089  1.00 55.29  ? 87  GLN C OE1 1 
ATOM 2285 N NE2 . GLN C 3 88  ? 138.857 128.284 93.467  1.00 55.29  ? 87  GLN C NE2 1 
ATOM 2286 N N   . ALA C 3 89  ? 136.612 123.640 97.540  1.00 46.88  ? 88  ALA C N   1 
ATOM 2287 C CA  . ALA C 3 89  ? 135.452 122.858 97.947  1.00 46.88  ? 88  ALA C CA  1 
ATOM 2288 C C   . ALA C 3 89  ? 134.197 123.698 97.763  1.00 46.88  ? 88  ALA C C   1 
ATOM 2289 O O   . ALA C 3 89  ? 134.133 124.834 98.244  1.00 46.88  ? 88  ALA C O   1 
ATOM 2290 C CB  . ALA C 3 89  ? 135.577 122.399 99.401  1.00 46.88  ? 88  ALA C CB  1 
ATOM 2291 N N   . TYR C 3 90  ? 133.207 123.141 97.077  1.00 42.66  ? 89  TYR C N   1 
ATOM 2292 C CA  . TYR C 3 90  ? 131.991 123.861 96.729  1.00 42.66  ? 89  TYR C CA  1 
ATOM 2293 C C   . TYR C 3 90  ? 130.800 123.328 97.514  1.00 42.66  ? 89  TYR C C   1 
ATOM 2294 O O   . TYR C 3 90  ? 130.865 122.290 98.176  1.00 42.66  ? 89  TYR C O   1 
ATOM 2295 C CB  . TYR C 3 90  ? 131.714 123.760 95.225  1.00 42.66  ? 89  TYR C CB  1 
ATOM 2296 C CG  . TYR C 3 90  ? 132.772 124.396 94.356  1.00 42.66  ? 89  TYR C CG  1 
ATOM 2297 C CD1 . TYR C 3 90  ? 133.193 125.697 94.582  1.00 42.66  ? 89  TYR C CD1 1 
ATOM 2298 C CD2 . TYR C 3 90  ? 133.344 123.696 93.304  1.00 42.66  ? 89  TYR C CD2 1 
ATOM 2299 C CE1 . TYR C 3 90  ? 134.158 126.282 93.788  1.00 42.66  ? 89  TYR C CE1 1 
ATOM 2300 C CE2 . TYR C 3 90  ? 134.310 124.272 92.505  1.00 42.66  ? 89  TYR C CE2 1 
ATOM 2301 C CZ  . TYR C 3 90  ? 134.713 125.565 92.751  1.00 42.66  ? 89  TYR C CZ  1 
ATOM 2302 O OH  . TYR C 3 90  ? 135.675 126.144 91.958  1.00 42.66  ? 89  TYR C OH  1 
ATOM 2303 N N   . ALA C 3 91  ? 129.699 124.071 97.427  1.00 38.36  ? 90  ALA C N   1 
ATOM 2304 C CA  . ALA C 3 91  ? 128.421 123.669 97.996  1.00 38.36  ? 90  ALA C CA  1 
ATOM 2305 C C   . ALA C 3 91  ? 127.331 124.477 97.310  1.00 38.36  ? 90  ALA C C   1 
ATOM 2306 O O   . ALA C 3 91  ? 127.603 125.494 96.669  1.00 38.36  ? 90  ALA C O   1 
ATOM 2307 C CB  . ALA C 3 91  ? 128.382 123.874 99.513  1.00 38.36  ? 90  ALA C CB  1 
ATOM 2308 N N   . ASP C 3 92  ? 126.092 124.012 97.450  1.00 36.22  ? 91  ASP C N   1 
ATOM 2309 C CA  . ASP C 3 92  ? 124.972 124.681 96.803  1.00 36.22  ? 91  ASP C CA  1 
ATOM 2310 C C   . ASP C 3 92  ? 123.674 124.230 97.454  1.00 36.22  ? 91  ASP C C   1 
ATOM 2311 O O   . ASP C 3 92  ? 123.528 123.060 97.813  1.00 36.22  ? 91  ASP C O   1 
ATOM 2312 C CB  . ASP C 3 92  ? 124.947 124.385 95.299  1.00 36.22  ? 91  ASP C CB  1 
ATOM 2313 C CG  . ASP C 3 92  ? 123.931 125.226 94.552  1.00 36.22  ? 91  ASP C CG  1 
ATOM 2314 O OD1 . ASP C 3 92  ? 122.719 125.080 94.814  1.00 36.22  ? 91  ASP C OD1 1 
ATOM 2315 O OD2 . ASP C 3 92  ? 124.345 126.035 93.696  1.00 36.22  ? 91  ASP C OD2 1 
ATOM 2316 N N   . VAL C 3 93  ? 122.743 125.168 97.605  1.00 33.50  ? 92  VAL C N   1 
ATOM 2317 C CA  . VAL C 3 93  ? 121.405 124.893 98.117  1.00 33.50  ? 92  VAL C CA  1 
ATOM 2318 C C   . VAL C 3 93  ? 120.407 125.612 97.223  1.00 33.50  ? 92  VAL C C   1 
ATOM 2319 O O   . VAL C 3 93  ? 120.661 126.734 96.774  1.00 33.50  ? 92  VAL C O   1 
ATOM 2320 C CB  . VAL C 3 93  ? 121.243 125.337 99.586  1.00 33.50  ? 92  VAL C CB  1 
ATOM 2321 C CG1 . VAL C 3 93  ? 119.894 124.900 100.129 1.00 33.50  ? 92  VAL C CG1 1 
ATOM 2322 C CG2 . VAL C 3 93  ? 122.363 124.781 100.448 1.00 33.50  ? 92  VAL C CG2 1 
ATOM 2323 N N   . THR C 3 94  ? 119.273 124.968 96.957  1.00 32.03  ? 93  THR C N   1 
ATOM 2324 C CA  . THR C 3 94  ? 118.257 125.550 96.086  1.00 32.03  ? 93  THR C CA  1 
ATOM 2325 C C   . THR C 3 94  ? 116.878 125.226 96.636  1.00 32.03  ? 93  THR C C   1 
ATOM 2326 O O   . THR C 3 94  ? 116.553 124.054 96.840  1.00 32.03  ? 93  THR C O   1 
ATOM 2327 C CB  . THR C 3 94  ? 118.394 125.029 94.655  1.00 32.03  ? 93  THR C CB  1 
ATOM 2328 O OG1 . THR C 3 94  ? 119.762 125.121 94.241  1.00 32.03  ? 93  THR C OG1 1 
ATOM 2329 C CG2 . THR C 3 94  ? 117.528 125.842 93.709  1.00 32.03  ? 93  THR C CG2 1 
ATOM 2330 N N   . PHE C 3 95  ? 116.074 126.259 96.869  1.00 35.36  ? 94  PHE C N   1 
ATOM 2331 C CA  . PHE C 3 95  ? 114.690 126.112 97.292  1.00 35.36  ? 94  PHE C CA  1 
ATOM 2332 C C   . PHE C 3 95  ? 113.773 126.630 96.192  1.00 35.36  ? 94  PHE C C   1 
ATOM 2333 O O   . PHE C 3 95  ? 114.088 127.623 95.530  1.00 35.36  ? 94  PHE C O   1 
ATOM 2334 C CB  . PHE C 3 95  ? 114.430 126.866 98.596  1.00 35.36  ? 94  PHE C CB  1 
ATOM 2335 C CG  . PHE C 3 95  ? 115.233 126.360 99.759  1.00 35.36  ? 94  PHE C CG  1 
ATOM 2336 C CD1 . PHE C 3 95  ? 114.948 125.135 100.333 1.00 35.36  ? 94  PHE C CD1 1 
ATOM 2337 C CD2 . PHE C 3 95  ? 116.273 127.109 100.278 1.00 35.36  ? 94  PHE C CD2 1 
ATOM 2338 C CE1 . PHE C 3 95  ? 115.684 124.668 101.404 1.00 35.36  ? 94  PHE C CE1 1 
ATOM 2339 C CE2 . PHE C 3 95  ? 117.011 126.647 101.348 1.00 35.36  ? 94  PHE C CE2 1 
ATOM 2340 C CZ  . PHE C 3 95  ? 116.717 125.425 101.911 1.00 35.36  ? 94  PHE C CZ  1 
ATOM 2341 N N   . SER C 3 96  ? 112.644 125.956 95.993  1.00 39.12  ? 95  SER C N   1 
ATOM 2342 C CA  . SER C 3 96  ? 111.759 126.227 94.863  1.00 39.12  ? 95  SER C CA  1 
ATOM 2343 C C   . SER C 3 96  ? 110.299 126.268 95.302  1.00 39.12  ? 95  SER C C   1 
ATOM 2344 O O   . SER C 3 96  ? 109.436 125.603 94.725  1.00 39.12  ? 95  SER C O   1 
ATOM 2345 C CB  . SER C 3 96  ? 111.959 125.191 93.763  1.00 39.12  ? 95  SER C CB  1 
ATOM 2346 O OG  . SER C 3 96  ? 110.850 125.168 92.882  1.00 39.12  ? 95  SER C OG  1 
ATOM 2347 N N   . PHE C 3 97  ? 110.000 127.047 96.339  1.00 45.71  ? 96  PHE C N   1 
ATOM 2348 C CA  . PHE C 3 97  ? 108.620 127.196 96.781  1.00 45.71  ? 96  PHE C CA  1 
ATOM 2349 C C   . PHE C 3 97  ? 107.768 127.840 95.685  1.00 45.71  ? 96  PHE C C   1 
ATOM 2350 O O   . PHE C 3 97  ? 108.270 128.362 94.688  1.00 45.71  ? 96  PHE C O   1 
ATOM 2351 C CB  . PHE C 3 97  ? 108.549 128.030 98.057  1.00 45.71  ? 96  PHE C CB  1 
ATOM 2352 C CG  . PHE C 3 97  ? 109.641 127.732 99.039  1.00 45.71  ? 96  PHE C CG  1 
ATOM 2353 C CD1 . PHE C 3 97  ? 109.657 126.536 99.733  1.00 45.71  ? 96  PHE C CD1 1 
ATOM 2354 C CD2 . PHE C 3 97  ? 110.644 128.653 99.278  1.00 45.71  ? 96  PHE C CD2 1 
ATOM 2355 C CE1 . PHE C 3 97  ? 110.658 126.260 100.640 1.00 45.71  ? 96  PHE C CE1 1 
ATOM 2356 C CE2 . PHE C 3 97  ? 111.647 128.383 100.184 1.00 45.71  ? 96  PHE C CE2 1 
ATOM 2357 C CZ  . PHE C 3 97  ? 111.654 127.185 100.866 1.00 45.71  ? 96  PHE C CZ  1 
ATOM 2358 N N   . THR C 3 98  ? 106.454 127.802 95.888  1.00 55.01  ? 97  THR C N   1 
ATOM 2359 C CA  . THR C 3 98  ? 105.487 128.292 94.916  1.00 55.01  ? 97  THR C CA  1 
ATOM 2360 C C   . THR C 3 98  ? 104.783 129.538 95.448  1.00 55.01  ? 97  THR C C   1 
ATOM 2361 O O   . THR C 3 98  ? 105.076 130.034 96.539  1.00 55.01  ? 97  THR C O   1 
ATOM 2362 C CB  . THR C 3 98  ? 104.475 127.200 94.565  1.00 55.01  ? 97  THR C CB  1 
ATOM 2363 O OG1 . THR C 3 98  ? 103.605 127.669 93.529  1.00 55.01  ? 97  THR C OG1 1 
ATOM 2364 C CG2 . THR C 3 98  ? 103.647 126.833 95.783  1.00 55.01  ? 97  THR C CG2 1 
ATOM 2365 N N   . GLN C 3 99  ? 103.836 130.043 94.653  1.00 61.40  ? 98  GLN C N   1 
ATOM 2366 C CA  . GLN C 3 99  ? 103.179 131.306 94.982  1.00 61.40  ? 98  GLN C CA  1 
ATOM 2367 C C   . GLN C 3 99  ? 102.255 131.166 96.185  1.00 61.40  ? 98  GLN C C   1 
ATOM 2368 O O   . GLN C 3 99  ? 102.209 132.055 97.042  1.00 61.40  ? 98  GLN C O   1 
ATOM 2369 C CB  . GLN C 3 99  ? 102.399 131.821 93.774  1.00 61.40  ? 98  GLN C CB  1 
ATOM 2370 C CG  . GLN C 3 99  ? 103.261 132.459 92.702  1.00 61.40  ? 98  GLN C CG  1 
ATOM 2371 C CD  . GLN C 3 99  ? 102.876 132.010 91.307  1.00 61.40  ? 98  GLN C CD  1 
ATOM 2372 O OE1 . GLN C 3 99  ? 101.710 131.725 91.034  1.00 61.40  ? 98  GLN C OE1 1 
ATOM 2373 N NE2 . GLN C 3 99  ? 103.858 131.941 90.414  1.00 61.40  ? 98  GLN C NE2 1 
ATOM 2374 N N   . TYR C 3 100 ? 101.509 130.069 96.264  1.00 60.04  ? 99  TYR C N   1 
ATOM 2375 C CA  . TYR C 3 100 ? 100.510 129.889 97.308  1.00 60.04  ? 99  TYR C CA  1 
ATOM 2376 C C   . TYR C 3 100 ? 101.056 129.200 98.551  1.00 60.04  ? 99  TYR C C   1 
ATOM 2377 O O   . TYR C 3 100 ? 100.288 128.940 99.481  1.00 60.04  ? 99  TYR C O   1 
ATOM 2378 C CB  . TYR C 3 100 ? 99.318  129.095 96.766  1.00 60.04  ? 99  TYR C CB  1 
ATOM 2379 C CG  . TYR C 3 100 ? 98.459  129.870 95.795  1.00 60.04  ? 99  TYR C CG  1 
ATOM 2380 C CD1 . TYR C 3 100 ? 97.420  130.671 96.244  1.00 60.04  ? 99  TYR C CD1 1 
ATOM 2381 C CD2 . TYR C 3 100 ? 98.687  129.799 94.428  1.00 60.04  ? 99  TYR C CD2 1 
ATOM 2382 C CE1 . TYR C 3 100 ? 96.632  131.381 95.361  1.00 60.04  ? 99  TYR C CE1 1 
ATOM 2383 C CE2 . TYR C 3 100 ? 97.905  130.506 93.537  1.00 60.04  ? 99  TYR C CE2 1 
ATOM 2384 C CZ  . TYR C 3 100 ? 96.880  131.295 94.009  1.00 60.04  ? 99  TYR C CZ  1 
ATOM 2385 O OH  . TYR C 3 100 ? 96.098  132.000 93.124  1.00 60.04  ? 99  TYR C OH  1 
ATOM 2386 N N   . SER C 3 101 ? 102.351 128.897 98.590  1.00 57.48  ? 100 SER C N   1 
ATOM 2387 C CA  . SER C 3 101 ? 102.927 128.231 99.751  1.00 57.48  ? 100 SER C CA  1 
ATOM 2388 C C   . SER C 3 101 ? 102.920 129.167 100.952 1.00 57.48  ? 100 SER C C   1 
ATOM 2389 O O   . SER C 3 101 ? 103.305 130.334 100.846 1.00 57.48  ? 100 SER C O   1 
ATOM 2390 C CB  . SER C 3 101 ? 104.350 127.773 99.446  1.00 57.48  ? 100 SER C CB  1 
ATOM 2391 O OG  . SER C 3 101 ? 105.209 128.885 99.265  1.00 57.48  ? 100 SER C OG  1 
ATOM 2392 N N   . THR C 3 102 ? 102.486 128.650 102.097 1.00 59.88  ? 101 THR C N   1 
ATOM 2393 C CA  . THR C 3 102 ? 102.386 129.448 103.311 1.00 59.88  ? 101 THR C CA  1 
ATOM 2394 C C   . THR C 3 102 ? 103.744 129.502 104.010 1.00 59.88  ? 101 THR C C   1 
ATOM 2395 O O   . THR C 3 102 ? 104.759 129.024 103.497 1.00 59.88  ? 101 THR C O   1 
ATOM 2396 C CB  . THR C 3 102 ? 101.300 128.889 104.225 1.00 59.88  ? 101 THR C CB  1 
ATOM 2397 O OG1 . THR C 3 102 ? 101.638 127.550 104.607 1.00 59.88  ? 101 THR C OG1 1 
ATOM 2398 C CG2 . THR C 3 102 ? 99.960  128.882 103.510 1.00 59.88  ? 101 THR C CG2 1 
ATOM 2399 N N   . ASP C 3 103 ? 103.771 130.099 105.203 1.00 59.13  ? 102 ASP C N   1 
ATOM 2400 C CA  . ASP C 3 103 ? 105.017 130.215 105.953 1.00 59.13  ? 102 ASP C CA  1 
ATOM 2401 C C   . ASP C 3 103 ? 105.408 128.870 106.556 1.00 59.13  ? 102 ASP C C   1 
ATOM 2402 O O   . ASP C 3 103 ? 106.590 128.498 106.552 1.00 59.13  ? 102 ASP C O   1 
ATOM 2403 C CB  . ASP C 3 103 ? 104.846 131.295 107.031 1.00 59.13  ? 102 ASP C CB  1 
ATOM 2404 C CG  . ASP C 3 103 ? 106.091 131.511 107.897 1.00 59.13  ? 102 ASP C CG  1 
ATOM 2405 O OD1 . ASP C 3 103 ? 106.983 130.645 107.980 1.00 59.13  ? 102 ASP C OD1 1 
ATOM 2406 O OD2 . ASP C 3 103 ? 106.171 132.592 108.518 1.00 59.13  ? 102 ASP C OD2 1 
ATOM 2407 N N   . GLU C 3 104 ? 104.423 128.114 107.046 1.00 60.20  ? 103 GLU C N   1 
ATOM 2408 C CA  . GLU C 3 104 ? 104.713 126.883 107.774 1.00 60.20  ? 103 GLU C CA  1 
ATOM 2409 C C   . GLU C 3 104 ? 105.421 125.860 106.895 1.00 60.20  ? 103 GLU C C   1 
ATOM 2410 O O   . GLU C 3 104 ? 106.336 125.172 107.357 1.00 60.20  ? 103 GLU C O   1 
ATOM 2411 C CB  . GLU C 3 104 ? 103.422 126.297 108.344 1.00 60.20  ? 103 GLU C CB  1 
ATOM 2412 C CG  . GLU C 3 104 ? 103.010 126.897 109.677 1.00 60.20  ? 103 GLU C CG  1 
ATOM 2413 C CD  . GLU C 3 104 ? 102.321 128.239 109.525 1.00 60.20  ? 103 GLU C CD  1 
ATOM 2414 O OE1 . GLU C 3 104 ? 102.028 128.633 108.377 1.00 60.20  ? 103 GLU C OE1 1 
ATOM 2415 O OE2 . GLU C 3 104 ? 102.073 128.901 110.554 1.00 60.20  ? 103 GLU C OE2 1 
ATOM 2416 N N   . GLU C 3 105 ? 105.013 125.739 105.631 1.00 58.08  ? 104 GLU C N   1 
ATOM 2417 C CA  . GLU C 3 105 ? 105.649 124.770 104.741 1.00 58.08  ? 104 GLU C CA  1 
ATOM 2418 C C   . GLU C 3 105 ? 107.121 125.104 104.524 1.00 58.08  ? 104 GLU C C   1 
ATOM 2419 O O   . GLU C 3 105 ? 107.990 124.225 104.601 1.00 58.08  ? 104 GLU C O   1 
ATOM 2420 C CB  . GLU C 3 105 ? 104.907 124.720 103.406 1.00 58.08  ? 104 GLU C CB  1 
ATOM 2421 C CG  . GLU C 3 105 ? 103.396 124.681 103.539 1.00 58.08  ? 104 GLU C CG  1 
ATOM 2422 C CD  . GLU C 3 105 ? 102.703 124.438 102.214 1.00 58.08  ? 104 GLU C CD  1 
ATOM 2423 O OE1 . GLU C 3 105 ? 103.407 124.235 101.203 1.00 58.08  ? 104 GLU C OE1 1 
ATOM 2424 O OE2 . GLU C 3 105 ? 101.454 124.451 102.183 1.00 58.08  ? 104 GLU C OE2 1 
ATOM 2425 N N   . ARG C 3 106 ? 107.419 126.375 104.250 1.00 50.31  ? 105 ARG C N   1 
ATOM 2426 C CA  . ARG C 3 106 ? 108.802 126.779 104.024 1.00 50.31  ? 105 ARG C CA  1 
ATOM 2427 C C   . ARG C 3 106 ? 109.641 126.597 105.281 1.00 50.31  ? 105 ARG C C   1 
ATOM 2428 O O   . ARG C 3 106 ? 110.786 126.130 105.212 1.00 50.31  ? 105 ARG C O   1 
ATOM 2429 C CB  . ARG C 3 106 ? 108.847 128.230 103.548 1.00 50.31  ? 105 ARG C CB  1 
ATOM 2430 C CG  . ARG C 3 106 ? 107.976 128.505 102.336 1.00 50.31  ? 105 ARG C CG  1 
ATOM 2431 C CD  . ARG C 3 106 ? 108.167 129.923 101.830 1.00 50.31  ? 105 ARG C CD  1 
ATOM 2432 N NE  . ARG C 3 106 ? 107.585 130.905 102.735 1.00 50.31  ? 105 ARG C NE  1 
ATOM 2433 C CZ  . ARG C 3 106 ? 106.516 131.636 102.457 1.00 50.31  ? 105 ARG C CZ  1 
ATOM 2434 N NH1 . ARG C 3 106 ? 105.883 131.522 101.301 1.00 50.31  ? 105 ARG C NH1 1 
ATOM 2435 N NH2 . ARG C 3 106 ? 106.070 132.504 103.360 1.00 50.31  ? 105 ARG C NH2 1 
ATOM 2436 N N   . ALA C 3 107 ? 109.089 126.962 106.440 1.00 47.09  ? 106 ALA C N   1 
ATOM 2437 C CA  . ALA C 3 107 ? 109.816 126.773 107.690 1.00 47.09  ? 106 ALA C CA  1 
ATOM 2438 C C   . ALA C 3 107 ? 110.077 125.297 107.955 1.00 47.09  ? 106 ALA C C   1 
ATOM 2439 O O   . ALA C 3 107 ? 111.165 124.922 108.407 1.00 47.09  ? 106 ALA C O   1 
ATOM 2440 C CB  . ALA C 3 107 ? 109.043 127.400 108.849 1.00 47.09  ? 106 ALA C CB  1 
ATOM 2441 N N   . PHE C 3 108 ? 109.088 124.444 107.678 1.00 44.11  ? 107 PHE C N   1 
ATOM 2442 C CA  . PHE C 3 108 ? 109.268 123.009 107.854 1.00 44.11  ? 107 PHE C CA  1 
ATOM 2443 C C   . PHE C 3 108 ? 110.372 122.480 106.954 1.00 44.11  ? 107 PHE C C   1 
ATOM 2444 O O   . PHE C 3 108 ? 111.214 121.692 107.395 1.00 44.11  ? 107 PHE C O   1 
ATOM 2445 C CB  . PHE C 3 108 ? 107.953 122.282 107.573 1.00 44.11  ? 107 PHE C CB  1 
ATOM 2446 C CG  . PHE C 3 108 ? 107.941 120.851 108.023 1.00 44.11  ? 107 PHE C CG  1 
ATOM 2447 C CD1 . PHE C 3 108 ? 108.419 119.848 107.198 1.00 44.11  ? 107 PHE C CD1 1 
ATOM 2448 C CD2 . PHE C 3 108 ? 107.447 120.508 109.268 1.00 44.11  ? 107 PHE C CD2 1 
ATOM 2449 C CE1 . PHE C 3 108 ? 108.407 118.531 107.608 1.00 44.11  ? 107 PHE C CE1 1 
ATOM 2450 C CE2 . PHE C 3 108 ? 107.433 119.193 109.684 1.00 44.11  ? 107 PHE C CE2 1 
ATOM 2451 C CZ  . PHE C 3 108 ? 107.913 118.203 108.853 1.00 44.11  ? 107 PHE C CZ  1 
ATOM 2452 N N   . VAL C 3 109 ? 110.391 122.908 105.689 1.00 42.48  ? 108 VAL C N   1 
ATOM 2453 C CA  . VAL C 3 109 ? 111.424 122.440 104.766 1.00 42.48  ? 108 VAL C CA  1 
ATOM 2454 C C   . VAL C 3 109 ? 112.804 122.881 105.242 1.00 42.48  ? 108 VAL C C   1 
ATOM 2455 O O   . VAL C 3 109 ? 113.758 122.092 105.258 1.00 42.48  ? 108 VAL C O   1 
ATOM 2456 C CB  . VAL C 3 109 ? 111.135 122.933 103.338 1.00 42.48  ? 108 VAL C CB  1 
ATOM 2457 C CG1 . VAL C 3 109 ? 112.335 122.691 102.441 1.00 42.48  ? 108 VAL C CG1 1 
ATOM 2458 C CG2 . VAL C 3 109 ? 109.907 122.238 102.780 1.00 42.48  ? 108 VAL C CG2 1 
ATOM 2459 N N   . ARG C 3 110 ? 112.928 124.148 105.648 1.00 41.99  ? 109 ARG C N   1 
ATOM 2460 C CA  . ARG C 3 110 ? 114.228 124.656 106.080 1.00 41.99  ? 109 ARG C CA  1 
ATOM 2461 C C   . ARG C 3 110 ? 114.716 123.935 107.332 1.00 41.99  ? 109 ARG C C   1 
ATOM 2462 O O   . ARG C 3 110 ? 115.884 123.536 107.416 1.00 41.99  ? 109 ARG C O   1 
ATOM 2463 C CB  . ARG C 3 110 ? 114.153 126.161 106.326 1.00 41.99  ? 109 ARG C CB  1 
ATOM 2464 C CG  . ARG C 3 110 ? 115.369 126.719 107.047 1.00 41.99  ? 109 ARG C CG  1 
ATOM 2465 C CD  . ARG C 3 110 ? 115.164 128.165 107.453 1.00 41.99  ? 109 ARG C CD  1 
ATOM 2466 N NE  . ARG C 3 110 ? 114.153 128.300 108.493 1.00 41.99  ? 109 ARG C NE  1 
ATOM 2467 C CZ  . ARG C 3 110 ? 114.376 128.100 109.784 1.00 41.99  ? 109 ARG C CZ  1 
ATOM 2468 N NH1 . ARG C 3 110 ? 115.569 127.748 110.233 1.00 41.99  ? 109 ARG C NH1 1 
ATOM 2469 N NH2 . ARG C 3 110 ? 113.377 128.258 110.648 1.00 41.99  ? 109 ARG C NH2 1 
ATOM 2470 N N   . THR C 3 111 ? 113.834 123.756 108.319 1.00 41.68  ? 110 THR C N   1 
ATOM 2471 C CA  . THR C 3 111 ? 114.239 123.085 109.549 1.00 41.68  ? 110 THR C CA  1 
ATOM 2472 C C   . THR C 3 111 ? 114.561 121.617 109.301 1.00 41.68  ? 110 THR C C   1 
ATOM 2473 O O   . THR C 3 111 ? 115.486 121.071 109.911 1.00 41.68  ? 110 THR C O   1 
ATOM 2474 C CB  . THR C 3 111 ? 113.155 123.222 110.616 1.00 41.68  ? 110 THR C CB  1 
ATOM 2475 O OG1 . THR C 3 111 ? 111.907 122.746 110.097 1.00 41.68  ? 110 THR C OG1 1 
ATOM 2476 C CG2 . THR C 3 111 ? 113.007 124.672 111.044 1.00 41.68  ? 110 THR C CG2 1 
ATOM 2477 N N   . GLU C 3 112 ? 113.809 120.959 108.414 1.00 40.36  ? 111 GLU C N   1 
ATOM 2478 C CA  . GLU C 3 112 ? 114.113 119.575 108.075 1.00 40.36  ? 111 GLU C CA  1 
ATOM 2479 C C   . GLU C 3 112 ? 115.482 119.458 107.424 1.00 40.36  ? 111 GLU C C   1 
ATOM 2480 O O   . GLU C 3 112 ? 116.258 118.554 107.753 1.00 40.36  ? 111 GLU C O   1 
ATOM 2481 C CB  . GLU C 3 112 ? 113.033 119.014 107.152 1.00 40.36  ? 111 GLU C CB  1 
ATOM 2482 C CG  . GLU C 3 112 ? 113.215 117.550 106.801 1.00 40.36  ? 111 GLU C CG  1 
ATOM 2483 C CD  . GLU C 3 112 ? 112.097 117.020 105.926 1.00 40.36  ? 111 GLU C CD  1 
ATOM 2484 O OE1 . GLU C 3 112 ? 111.191 117.805 105.578 1.00 40.36  ? 111 GLU C OE1 1 
ATOM 2485 O OE2 . GLU C 3 112 ? 112.125 115.820 105.584 1.00 40.36  ? 111 GLU C OE2 1 
ATOM 2486 N N   . LEU C 3 113 ? 115.801 120.366 106.499 1.00 38.48  ? 112 LEU C N   1 
ATOM 2487 C CA  . LEU C 3 113 ? 117.116 120.331 105.868 1.00 38.48  ? 112 LEU C CA  1 
ATOM 2488 C C   . LEU C 3 113 ? 118.221 120.611 106.878 1.00 38.48  ? 112 LEU C C   1 
ATOM 2489 O O   . LEU C 3 113 ? 119.289 119.990 106.825 1.00 38.48  ? 112 LEU C O   1 
ATOM 2490 C CB  . LEU C 3 113 ? 117.176 121.330 104.715 1.00 38.48  ? 112 LEU C CB  1 
ATOM 2491 C CG  . LEU C 3 113 ? 118.452 121.295 103.872 1.00 38.48  ? 112 LEU C CG  1 
ATOM 2492 C CD1 . LEU C 3 113 ? 118.816 119.868 103.502 1.00 38.48  ? 112 LEU C CD1 1 
ATOM 2493 C CD2 . LEU C 3 113 ? 118.294 122.149 102.626 1.00 38.48  ? 112 LEU C CD2 1 
ATOM 2494 N N   . ALA C 3 114 ? 117.989 121.546 107.801 1.00 40.38  ? 113 ALA C N   1 
ATOM 2495 C CA  . ALA C 3 114 ? 119.007 121.867 108.798 1.00 40.38  ? 113 ALA C CA  1 
ATOM 2496 C C   . ALA C 3 114 ? 119.247 120.703 109.752 1.00 40.38  ? 113 ALA C C   1 
ATOM 2497 O O   . ALA C 3 114 ? 120.396 120.393 110.083 1.00 40.38  ? 113 ALA C O   1 
ATOM 2498 C CB  . ALA C 3 114 ? 118.604 123.120 109.574 1.00 40.38  ? 113 ALA C CB  1 
ATOM 2499 N N   . ALA C 3 115 ? 118.177 120.048 110.209 1.00 38.33  ? 114 ALA C N   1 
ATOM 2500 C CA  . ALA C 3 115 ? 118.320 118.977 111.189 1.00 38.33  ? 114 ALA C CA  1 
ATOM 2501 C C   . ALA C 3 115 ? 118.829 117.688 110.555 1.00 38.33  ? 114 ALA C C   1 
ATOM 2502 O O   . ALA C 3 115 ? 119.613 116.960 111.172 1.00 38.33  ? 114 ALA C O   1 
ATOM 2503 C CB  . ALA C 3 115 ? 116.987 118.730 111.894 1.00 38.33  ? 114 ALA C CB  1 
ATOM 2504 N N   . LEU C 3 116 ? 118.391 117.388 109.332 1.00 37.71  ? 115 LEU C N   1 
ATOM 2505 C CA  . LEU C 3 116 ? 118.809 116.162 108.662 1.00 37.71  ? 115 LEU C CA  1 
ATOM 2506 C C   . LEU C 3 116 ? 120.299 116.152 108.352 1.00 37.71  ? 115 LEU C C   1 
ATOM 2507 O O   . LEU C 3 116 ? 120.896 115.074 108.263 1.00 37.71  ? 115 LEU C O   1 
ATOM 2508 C CB  . LEU C 3 116 ? 117.992 115.980 107.381 1.00 37.71  ? 115 LEU C CB  1 
ATOM 2509 C CG  . LEU C 3 116 ? 118.498 115.057 106.275 1.00 37.71  ? 115 LEU C CG  1 
ATOM 2510 C CD1 . LEU C 3 116 ? 118.374 113.606 106.702 1.00 37.71  ? 115 LEU C CD1 1 
ATOM 2511 C CD2 . LEU C 3 116 ? 117.733 115.308 104.989 1.00 37.71  ? 115 LEU C CD2 1 
ATOM 2512 N N   . LEU C 3 117 ? 120.917 117.324 108.213 1.00 38.65  ? 116 LEU C N   1 
ATOM 2513 C CA  . LEU C 3 117 ? 122.327 117.415 107.863 1.00 38.65  ? 116 LEU C CA  1 
ATOM 2514 C C   . LEU C 3 117 ? 123.254 117.063 109.020 1.00 38.65  ? 116 LEU C C   1 
ATOM 2515 O O   . LEU C 3 117 ? 124.462 116.931 108.802 1.00 38.65  ? 116 LEU C O   1 
ATOM 2516 C CB  . LEU C 3 117 ? 122.643 118.824 107.358 1.00 38.65  ? 116 LEU C CB  1 
ATOM 2517 C CG  . LEU C 3 117 ? 123.760 118.960 106.326 1.00 38.65  ? 116 LEU C CG  1 
ATOM 2518 C CD1 . LEU C 3 117 ? 123.468 118.099 105.112 1.00 38.65  ? 116 LEU C CD1 1 
ATOM 2519 C CD2 . LEU C 3 117 ? 123.922 120.412 105.921 1.00 38.65  ? 116 LEU C CD2 1 
ATOM 2520 N N   . ALA C 3 118 ? 122.728 116.917 110.235 1.00 40.22  ? 117 ALA C N   1 
ATOM 2521 C CA  . ALA C 3 118 ? 123.517 116.500 111.387 1.00 40.22  ? 117 ALA C CA  1 
ATOM 2522 C C   . ALA C 3 118 ? 123.269 115.046 111.765 1.00 40.22  ? 117 ALA C C   1 
ATOM 2523 O O   . ALA C 3 118 ? 123.810 114.575 112.771 1.00 40.22  ? 117 ALA C O   1 
ATOM 2524 C CB  . ALA C 3 118 ? 123.231 117.410 112.583 1.00 40.22  ? 117 ALA C CB  1 
ATOM 2525 N N   . SER C 3 119 ? 122.463 114.328 110.988 1.00 46.46  ? 118 SER C N   1 
ATOM 2526 C CA  . SER C 3 119 ? 122.196 112.927 111.256 1.00 46.46  ? 118 SER C CA  1 
ATOM 2527 C C   . SER C 3 119 ? 123.433 112.084 110.953 1.00 46.46  ? 118 SER C C   1 
ATOM 2528 O O   . SER C 3 119 ? 124.270 112.468 110.133 1.00 46.46  ? 118 SER C O   1 
ATOM 2529 C CB  . SER C 3 119 ? 121.011 112.453 110.417 1.00 46.46  ? 118 SER C CB  1 
ATOM 2530 O OG  . SER C 3 119 ? 120.745 111.078 110.620 1.00 46.46  ? 118 SER C OG  1 
ATOM 2531 N N   . PRO C 3 120 ? 123.576 110.932 111.615 1.00 52.45  ? 119 PRO C N   1 
ATOM 2532 C CA  . PRO C 3 120 ? 124.729 110.063 111.323 1.00 52.45  ? 119 PRO C CA  1 
ATOM 2533 C C   . PRO C 3 120 ? 124.828 109.641 109.868 1.00 52.45  ? 119 PRO C C   1 
ATOM 2534 O O   . PRO C 3 120 ? 125.942 109.450 109.365 1.00 52.45  ? 119 PRO C O   1 
ATOM 2535 C CB  . PRO C 3 120 ? 124.492 108.860 112.243 1.00 52.45  ? 119 PRO C CB  1 
ATOM 2536 C CG  . PRO C 3 120 ? 123.755 109.428 113.397 1.00 52.45  ? 119 PRO C CG  1 
ATOM 2537 C CD  . PRO C 3 120 ? 122.867 110.510 112.836 1.00 52.45  ? 119 PRO C CD  1 
ATOM 2538 N N   . LEU C 3 121 ? 123.698 109.489 109.175 1.00 52.58  ? 120 LEU C N   1 
ATOM 2539 C CA  . LEU C 3 121 ? 123.737 109.088 107.772 1.00 52.58  ? 120 LEU C CA  1 
ATOM 2540 C C   . LEU C 3 121 ? 124.474 110.117 106.923 1.00 52.58  ? 120 LEU C C   1 
ATOM 2541 O O   . LEU C 3 121 ? 125.369 109.770 106.143 1.00 52.58  ? 120 LEU C O   1 
ATOM 2542 C CB  . LEU C 3 121 ? 122.315 108.878 107.253 1.00 52.58  ? 120 LEU C CB  1 
ATOM 2543 C CG  . LEU C 3 121 ? 122.154 108.774 105.736 1.00 52.58  ? 120 LEU C CG  1 
ATOM 2544 C CD1 . LEU C 3 121 ? 122.833 107.521 105.208 1.00 52.58  ? 120 LEU C CD1 1 
ATOM 2545 C CD2 . LEU C 3 121 ? 120.684 108.792 105.354 1.00 52.58  ? 120 LEU C CD2 1 
ATOM 2546 N N   . LEU C 3 122 ? 124.122 111.396 107.072 1.00 48.41  ? 121 LEU C N   1 
ATOM 2547 C CA  . LEU C 3 122 ? 124.748 112.430 106.254 1.00 48.41  ? 121 LEU C CA  1 
ATOM 2548 C C   . LEU C 3 122 ? 126.209 112.639 106.632 1.00 48.41  ? 121 LEU C C   1 
ATOM 2549 O O   . LEU C 3 122 ? 127.056 112.848 105.755 1.00 48.41  ? 121 LEU C O   1 
ATOM 2550 C CB  . LEU C 3 122 ? 123.972 113.741 106.365 1.00 48.41  ? 121 LEU C CB  1 
ATOM 2551 C CG  . LEU C 3 122 ? 122.832 113.961 105.368 1.00 48.41  ? 121 LEU C CG  1 
ATOM 2552 C CD1 . LEU C 3 122 ? 123.384 114.047 103.955 1.00 48.41  ? 121 LEU C CD1 1 
ATOM 2553 C CD2 . LEU C 3 122 ? 121.775 112.873 105.464 1.00 48.41  ? 121 LEU C CD2 1 
ATOM 2554 N N   . ILE C 3 123 ? 126.530 112.594 107.928 1.00 50.50  ? 122 ILE C N   1 
ATOM 2555 C CA  . ILE C 3 123 ? 127.923 112.761 108.319 1.00 50.50  ? 122 ILE C CA  1 
ATOM 2556 C C   . ILE C 3 123 ? 128.773 111.597 107.829 1.00 50.50  ? 122 ILE C C   1 
ATOM 2557 O O   . ILE C 3 123 ? 129.926 111.803 107.439 1.00 50.50  ? 122 ILE C O   1 
ATOM 2558 C CB  . ILE C 3 123 ? 128.065 112.959 109.842 1.00 50.50  ? 122 ILE C CB  1 
ATOM 2559 C CG1 . ILE C 3 123 ? 127.852 111.652 110.603 1.00 50.50  ? 122 ILE C CG1 1 
ATOM 2560 C CG2 . ILE C 3 123 ? 127.092 114.013 110.333 1.00 50.50  ? 122 ILE C CG2 1 
ATOM 2561 C CD1 . ILE C 3 123 ? 128.193 111.746 112.071 1.00 50.50  ? 122 ILE C CD1 1 
ATOM 2562 N N   . ASP C 3 124 ? 128.231 110.377 107.813 1.00 53.99  ? 123 ASP C N   1 
ATOM 2563 C CA  . ASP C 3 124 ? 128.960 109.261 107.223 1.00 53.99  ? 123 ASP C CA  1 
ATOM 2564 C C   . ASP C 3 124 ? 129.117 109.433 105.718 1.00 53.99  ? 123 ASP C C   1 
ATOM 2565 O O   . ASP C 3 124 ? 130.192 109.168 105.170 1.00 53.99  ? 123 ASP C O   1 
ATOM 2566 C CB  . ASP C 3 124 ? 128.255 107.942 107.536 1.00 53.99  ? 123 ASP C CB  1 
ATOM 2567 C CG  . ASP C 3 124 ? 128.702 107.341 108.852 1.00 53.99  ? 123 ASP C CG  1 
ATOM 2568 O OD1 . ASP C 3 124 ? 129.860 107.580 109.252 1.00 53.99  ? 123 ASP C OD1 1 
ATOM 2569 O OD2 . ASP C 3 124 ? 127.896 106.629 109.487 1.00 53.99  ? 123 ASP C OD2 1 
ATOM 2570 N N   . ALA C 3 125 ? 128.063 109.886 105.035 1.00 50.00  ? 124 ALA C N   1 
ATOM 2571 C CA  . ALA C 3 125 ? 128.116 110.008 103.584 1.00 50.00  ? 124 ALA C CA  1 
ATOM 2572 C C   . ALA C 3 125 ? 129.013 111.147 103.120 1.00 50.00  ? 124 ALA C C   1 
ATOM 2573 O O   . ALA C 3 125 ? 129.491 111.112 101.982 1.00 50.00  ? 124 ALA C O   1 
ATOM 2574 C CB  . ALA C 3 125 ? 126.708 110.197 103.020 1.00 50.00  ? 124 ALA C CB  1 
ATOM 2575 N N   . ILE C 3 126 ? 129.248 112.152 103.956 1.00 50.40  ? 125 ILE C N   1 
ATOM 2576 C CA  . ILE C 3 126 ? 130.064 113.302 103.574 1.00 50.40  ? 125 ILE C CA  1 
ATOM 2577 C C   . ILE C 3 126 ? 131.489 113.188 104.101 1.00 50.40  ? 125 ILE C C   1 
ATOM 2578 O O   . ILE C 3 126 ? 132.448 113.342 103.346 1.00 50.40  ? 125 ILE C O   1 
ATOM 2579 C CB  . ILE C 3 126 ? 129.398 114.614 104.043 1.00 50.40  ? 125 ILE C CB  1 
ATOM 2580 C CG1 . ILE C 3 126 ? 128.042 114.793 103.360 1.00 50.40  ? 125 ILE C CG1 1 
ATOM 2581 C CG2 . ILE C 3 126 ? 130.297 115.799 103.749 1.00 50.40  ? 125 ILE C CG2 1 
ATOM 2582 C CD1 . ILE C 3 126 ? 127.200 115.893 103.960 1.00 50.40  ? 125 ILE C CD1 1 
ATOM 2583 N N   . ASP C 3 127 ? 131.651 112.925 105.400 1.00 54.37  ? 126 ASP C N   1 
ATOM 2584 C CA  . ASP C 3 127 ? 132.989 112.884 105.981 1.00 54.37  ? 126 ASP C CA  1 
ATOM 2585 C C   . ASP C 3 127 ? 133.806 111.722 105.431 1.00 54.37  ? 126 ASP C C   1 
ATOM 2586 O O   . ASP C 3 127 ? 135.008 111.867 105.180 1.00 54.37  ? 126 ASP C O   1 
ATOM 2587 C CB  . ASP C 3 127 ? 132.896 112.801 107.504 1.00 54.37  ? 126 ASP C CB  1 
ATOM 2588 C CG  . ASP C 3 127 ? 132.631 114.148 108.143 1.00 54.37  ? 126 ASP C CG  1 
ATOM 2589 O OD1 . ASP C 3 127 ? 131.948 114.981 107.513 1.00 54.37  ? 126 ASP C OD1 1 
ATOM 2590 O OD2 . ASP C 3 127 ? 133.107 114.375 109.276 1.00 54.37  ? 126 ASP C OD2 1 
ATOM 2591 N N   . GLN C 3 128 ? 133.179 110.562 105.238 1.00 58.07  ? 127 GLN C N   1 
ATOM 2592 C CA  . GLN C 3 128 ? 133.879 109.377 104.765 1.00 58.07  ? 127 GLN C CA  1 
ATOM 2593 C C   . GLN C 3 128 ? 133.608 109.049 103.304 1.00 58.07  ? 127 GLN C C   1 
ATOM 2594 O O   . GLN C 3 128 ? 134.332 108.228 102.731 1.00 58.07  ? 127 GLN C O   1 
ATOM 2595 C CB  . GLN C 3 128 ? 133.512 108.164 105.632 1.00 58.07  ? 127 GLN C CB  1 
ATOM 2596 C CG  . GLN C 3 128 ? 133.280 108.495 107.098 1.00 58.07  ? 127 GLN C CG  1 
ATOM 2597 C CD  . GLN C 3 128 ? 134.569 108.690 107.874 1.00 58.07  ? 127 GLN C CD  1 
ATOM 2598 O OE1 . GLN C 3 128 ? 135.655 108.747 107.299 1.00 58.07  ? 127 GLN C OE1 1 
ATOM 2599 N NE2 . GLN C 3 128 ? 134.452 108.797 109.192 1.00 58.07  ? 127 GLN C NE2 1 
ATOM 2600 N N   . LEU C 3 129 ? 132.594 109.663 102.692 1.00 52.87  ? 128 LEU C N   1 
ATOM 2601 C CA  . LEU C 3 129 ? 132.280 109.472 101.274 1.00 52.87  ? 128 LEU C CA  1 
ATOM 2602 C C   . LEU C 3 129 ? 132.030 108.001 100.942 1.00 52.87  ? 128 LEU C C   1 
ATOM 2603 O O   . LEU C 3 129 ? 132.593 107.451 99.994  1.00 52.87  ? 128 LEU C O   1 
ATOM 2604 C CB  . LEU C 3 129 ? 133.383 110.051 100.386 1.00 52.87  ? 128 LEU C CB  1 
ATOM 2605 C CG  . LEU C 3 129 ? 133.442 111.574 100.272 1.00 52.87  ? 128 LEU C CG  1 
ATOM 2606 C CD1 . LEU C 3 129 ? 134.829 112.017 99.847  1.00 52.87  ? 128 LEU C CD1 1 
ATOM 2607 C CD2 . LEU C 3 129 ? 132.394 112.079 99.295  1.00 52.87  ? 128 LEU C CD2 1 
ATOM 2608 N N   . ASN C 3 130 ? 131.172 107.361 101.732 1.00 55.21  ? 129 ASN C N   1 
ATOM 2609 C CA  . ASN C 3 130 ? 130.776 105.991 101.470 1.00 55.21  ? 129 ASN C CA  1 
ATOM 2610 C C   . ASN C 3 130 ? 129.291 105.925 101.137 1.00 55.21  ? 129 ASN C C   1 
ATOM 2611 O O   . ASN C 3 130 ? 128.480 106.588 101.799 1.00 55.21  ? 129 ASN C O   1 
ATOM 2612 C CB  . ASN C 3 130 ? 131.097 105.074 102.669 1.00 55.21  ? 129 ASN C CB  1 
ATOM 2613 C CG  . ASN C 3 130 ? 130.555 105.603 103.981 1.00 55.21  ? 129 ASN C CG  1 
ATOM 2614 O OD1 . ASN C 3 130 ? 129.915 106.649 104.029 1.00 55.21  ? 129 ASN C OD1 1 
ATOM 2615 N ND2 . ASN C 3 130 ? 130.811 104.871 105.059 1.00 55.21  ? 129 ASN C ND2 1 
ATOM 2616 N N   . PRO C 3 131 ? 128.898 105.167 100.114 1.00 53.64  ? 130 PRO C N   1 
ATOM 2617 C CA  . PRO C 3 131 ? 127.477 105.087 99.759  1.00 53.64  ? 130 PRO C CA  1 
ATOM 2618 C C   . PRO C 3 131 ? 126.650 104.476 100.878 1.00 53.64  ? 130 PRO C C   1 
ATOM 2619 O O   . PRO C 3 131 ? 127.122 103.632 101.644 1.00 53.64  ? 130 PRO C O   1 
ATOM 2620 C CB  . PRO C 3 131 ? 127.473 104.198 98.510  1.00 53.64  ? 130 PRO C CB  1 
ATOM 2621 C CG  . PRO C 3 131 ? 128.854 104.313 97.957  1.00 53.64  ? 130 PRO C CG  1 
ATOM 2622 C CD  . PRO C 3 131 ? 129.752 104.462 99.146  1.00 53.64  ? 130 PRO C CD  1 
ATOM 2623 N N   . ALA C 3 132 ? 125.400 104.917 100.967 1.00 56.56  ? 131 ALA C N   1 
ATOM 2624 C CA  . ALA C 3 132 ? 124.484 104.434 101.993 1.00 56.56  ? 131 ALA C CA  1 
ATOM 2625 C C   . ALA C 3 132 ? 124.091 102.983 101.741 1.00 56.56  ? 131 ALA C C   1 
ATOM 2626 O O   . ALA C 3 132 ? 123.681 102.623 100.638 1.00 56.56  ? 131 ALA C O   1 
ATOM 2627 C CB  . ALA C 3 132 ? 123.249 105.314 102.055 1.00 56.56  ? 131 ALA C CB  1 
ATOM 2628 N N   . ALA D 3 2   ? 127.584 102.809 105.733 1.00 65.87  ? 1   ALA c N   1 
ATOM 2629 C CA  . ALA D 3 2   ? 126.421 103.203 106.519 1.00 65.87  ? 1   ALA c CA  1 
ATOM 2630 C C   . ALA D 3 2   ? 125.158 102.527 106.000 1.00 65.87  ? 1   ALA c C   1 
ATOM 2631 O O   . ALA D 3 2   ? 124.561 102.975 105.022 1.00 65.87  ? 1   ALA c O   1 
ATOM 2632 C CB  . ALA D 3 2   ? 126.259 104.713 106.503 1.00 65.87  ? 1   ALA c CB  1 
ATOM 2633 N N   . LYS D 3 3   ? 124.757 101.443 106.660 1.00 64.25  ? 2   LYS c N   1 
ATOM 2634 C CA  . LYS D 3 3   ? 123.556 100.725 106.261 1.00 64.25  ? 2   LYS c CA  1 
ATOM 2635 C C   . LYS D 3 3   ? 122.316 101.565 106.540 1.00 64.25  ? 2   LYS c C   1 
ATOM 2636 O O   . LYS D 3 3   ? 122.258 102.308 107.523 1.00 64.25  ? 2   LYS c O   1 
ATOM 2637 C CB  . LYS D 3 3   ? 123.467 99.390  106.998 1.00 64.25  ? 2   LYS c CB  1 
ATOM 2638 C CG  . LYS D 3 3   ? 122.400 98.450  106.462 1.00 64.25  ? 2   LYS c CG  1 
ATOM 2639 C CD  . LYS D 3 3   ? 122.444 97.104  107.165 1.00 64.25  ? 2   LYS c CD  1 
ATOM 2640 C CE  . LYS D 3 3   ? 121.305 96.206  106.710 1.00 64.25  ? 2   LYS c CE  1 
ATOM 2641 N NZ  . LYS D 3 3   ? 121.438 95.815  105.279 1.00 64.25  ? 2   LYS c NZ  1 
ATOM 2642 N N   . LEU D 3 4   ? 121.323 101.446 105.664 1.00 60.54  ? 3   LEU c N   1 
ATOM 2643 C CA  . LEU D 3 4   ? 120.090 102.203 105.819 1.00 60.54  ? 3   LEU c CA  1 
ATOM 2644 C C   . LEU D 3 4   ? 119.322 101.746 107.055 1.00 60.54  ? 3   LEU c C   1 
ATOM 2645 O O   . LEU D 3 4   ? 119.309 100.564 107.408 1.00 60.54  ? 3   LEU c O   1 
ATOM 2646 C CB  . LEU D 3 4   ? 119.212 102.052 104.577 1.00 60.54  ? 3   LEU c CB  1 
ATOM 2647 C CG  . LEU D 3 4   ? 119.642 102.844 103.343 1.00 60.54  ? 3   LEU c CG  1 
ATOM 2648 C CD1 . LEU D 3 4   ? 118.733 102.533 102.166 1.00 60.54  ? 3   LEU c CD1 1 
ATOM 2649 C CD2 . LEU D 3 4   ? 119.648 104.333 103.639 1.00 60.54  ? 3   LEU c CD2 1 
ATOM 2650 N N   . GLU D 3 5   ? 118.678 102.705 107.714 1.00 60.30  ? 4   GLU c N   1 
ATOM 2651 C CA  . GLU D 3 5   ? 117.882 102.427 108.902 1.00 60.30  ? 4   GLU c CA  1 
ATOM 2652 C C   . GLU D 3 5   ? 116.922 103.587 109.119 1.00 60.30  ? 4   GLU c C   1 
ATOM 2653 O O   . GLU D 3 5   ? 117.012 104.624 108.459 1.00 60.30  ? 4   GLU c O   1 
ATOM 2654 C CB  . GLU D 3 5   ? 118.767 102.207 110.132 1.00 60.30  ? 4   GLU c CB  1 
ATOM 2655 C CG  . GLU D 3 5   ? 119.909 103.199 110.257 1.00 60.30  ? 4   GLU c CG  1 
ATOM 2656 C CD  . GLU D 3 5   ? 120.926 102.785 111.302 1.00 60.30  ? 4   GLU c CD  1 
ATOM 2657 O OE1 . GLU D 3 5   ? 120.945 101.594 111.675 1.00 60.30  ? 4   GLU c OE1 1 
ATOM 2658 O OE2 . GLU D 3 5   ? 121.708 103.651 111.748 1.00 60.30  ? 4   GLU c OE2 1 
ATOM 2659 N N   . THR D 3 6   ? 115.996 103.395 110.054 1.00 51.88  ? 5   THR c N   1 
ATOM 2660 C CA  . THR D 3 6   ? 115.022 104.432 110.364 1.00 51.88  ? 5   THR c CA  1 
ATOM 2661 C C   . THR D 3 6   ? 115.709 105.651 110.965 1.00 51.88  ? 5   THR c C   1 
ATOM 2662 O O   . THR D 3 6   ? 116.591 105.531 111.819 1.00 51.88  ? 5   THR c O   1 
ATOM 2663 C CB  . THR D 3 6   ? 113.965 103.903 111.331 1.00 51.88  ? 5   THR c CB  1 
ATOM 2664 O OG1 . THR D 3 6   ? 114.585 103.556 112.575 1.00 51.88  ? 5   THR c OG1 1 
ATOM 2665 C CG2 . THR D 3 6   ? 113.281 102.676 110.753 1.00 51.88  ? 5   THR c CG2 1 
ATOM 2666 N N   . VAL D 3 7   ? 115.295 106.831 110.512 1.00 47.49  ? 6   VAL c N   1 
ATOM 2667 C CA  . VAL D 3 7   ? 115.840 108.101 110.973 1.00 47.49  ? 6   VAL c CA  1 
ATOM 2668 C C   . VAL D 3 7   ? 114.711 108.899 111.606 1.00 47.49  ? 6   VAL c C   1 
ATOM 2669 O O   . VAL D 3 7   ? 113.640 109.048 111.006 1.00 47.49  ? 6   VAL c O   1 
ATOM 2670 C CB  . VAL D 3 7   ? 116.489 108.891 109.822 1.00 47.49  ? 6   VAL c CB  1 
ATOM 2671 C CG1 . VAL D 3 7   ? 117.109 110.176 110.342 1.00 47.49  ? 6   VAL c CG1 1 
ATOM 2672 C CG2 . VAL D 3 7   ? 117.529 108.040 109.115 1.00 47.49  ? 6   VAL c CG2 1 
ATOM 2673 N N   . THR D 3 8   ? 114.943 109.399 112.816 1.00 46.58  ? 7   THR c N   1 
ATOM 2674 C CA  . THR D 3 8   ? 113.954 110.187 113.549 1.00 46.58  ? 7   THR c CA  1 
ATOM 2675 C C   . THR D 3 8   ? 114.544 111.567 113.819 1.00 46.58  ? 7   THR c C   1 
ATOM 2676 O O   . THR D 3 8   ? 115.410 111.720 114.686 1.00 46.58  ? 7   THR c O   1 
ATOM 2677 C CB  . THR D 3 8   ? 113.552 109.498 114.849 1.00 46.58  ? 7   THR c CB  1 
ATOM 2678 O OG1 . THR D 3 8   ? 114.666 109.492 115.749 1.00 46.58  ? 7   THR c OG1 1 
ATOM 2679 C CG2 . THR D 3 8   ? 113.124 108.067 114.585 1.00 46.58  ? 7   THR c CG2 1 
ATOM 2680 N N   . LEU D 3 9   ? 114.079 112.567 113.078 1.00 44.66  ? 8   LEU c N   1 
ATOM 2681 C CA  . LEU D 3 9   ? 114.496 113.941 113.310 1.00 44.66  ? 8   LEU c CA  1 
ATOM 2682 C C   . LEU D 3 9   ? 113.627 114.579 114.384 1.00 44.66  ? 8   LEU c C   1 
ATOM 2683 O O   . LEU D 3 9   ? 112.411 114.378 114.416 1.00 44.66  ? 8   LEU c O   1 
ATOM 2684 C CB  . LEU D 3 9   ? 114.413 114.751 112.018 1.00 44.66  ? 8   LEU c CB  1 
ATOM 2685 C CG  . LEU D 3 9   ? 115.067 114.112 110.794 1.00 44.66  ? 8   LEU c CG  1 
ATOM 2686 C CD1 . LEU D 3 9   ? 114.607 114.794 109.519 1.00 44.66  ? 8   LEU c CD1 1 
ATOM 2687 C CD2 . LEU D 3 9   ? 116.579 114.160 110.918 1.00 44.66  ? 8   LEU c CD2 1 
ATOM 2688 N N   . GLY D 3 10  ? 114.257 115.355 115.266 1.00 43.40  ? 9   GLY c N   1 
ATOM 2689 C CA  . GLY D 3 10  ? 113.550 115.989 116.353 1.00 43.40  ? 9   GLY c CA  1 
ATOM 2690 C C   . GLY D 3 10  ? 113.801 117.484 116.379 1.00 43.40  ? 9   GLY c C   1 
ATOM 2691 O O   . GLY D 3 10  ? 114.773 117.987 115.815 1.00 43.40  ? 9   GLY c O   1 
ATOM 2692 N N   . LYS D 3 11  ? 112.893 118.190 117.055 1.00 43.98  ? 10  LYS c N   1 
ATOM 2693 C CA  . LYS D 3 11  ? 112.963 119.644 117.211 1.00 43.98  ? 10  LYS c CA  1 
ATOM 2694 C C   . LYS D 3 11  ? 112.989 120.340 115.849 1.00 43.98  ? 10  LYS c C   1 
ATOM 2695 O O   . LYS D 3 11  ? 113.979 120.960 115.454 1.00 43.98  ? 10  LYS c O   1 
ATOM 2696 C CB  . LYS D 3 11  ? 114.167 120.053 118.068 1.00 43.98  ? 10  LYS c CB  1 
ATOM 2697 C CG  . LYS D 3 11  ? 114.225 121.542 118.401 1.00 43.98  ? 10  LYS c CG  1 
ATOM 2698 C CD  . LYS D 3 11  ? 115.587 121.947 118.940 1.00 43.98  ? 10  LYS c CD  1 
ATOM 2699 C CE  . LYS D 3 11  ? 115.516 122.308 120.414 1.00 43.98  ? 10  LYS c CE  1 
ATOM 2700 N NZ  . LYS D 3 11  ? 116.862 122.318 121.049 1.00 43.98  ? 10  LYS c NZ  1 
ATOM 2701 N N   . ILE D 3 12  ? 111.891 120.206 115.111 1.00 43.77  ? 11  ILE c N   1 
ATOM 2702 C CA  . ILE D 3 12  ? 111.725 120.875 113.830 1.00 43.77  ? 11  ILE c CA  1 
ATOM 2703 C C   . ILE D 3 12  ? 110.398 121.624 113.844 1.00 43.77  ? 11  ILE c C   1 
ATOM 2704 O O   . ILE D 3 12  ? 109.611 121.528 114.785 1.00 43.77  ? 11  ILE c O   1 
ATOM 2705 C CB  . ILE D 3 12  ? 111.780 119.902 112.641 1.00 43.77  ? 11  ILE c CB  1 
ATOM 2706 C CG1 . ILE D 3 12  ? 110.589 118.953 112.688 1.00 43.77  ? 11  ILE c CG1 1 
ATOM 2707 C CG2 . ILE D 3 12  ? 113.080 119.121 112.647 1.00 43.77  ? 11  ILE c CG2 1 
ATOM 2708 C CD1 . ILE D 3 12  ? 110.412 118.171 111.429 1.00 43.77  ? 11  ILE c CD1 1 
ATOM 2709 N N   . GLY D 3 13  ? 110.160 122.373 112.779 1.00 45.27  ? 12  GLY c N   1 
ATOM 2710 C CA  . GLY D 3 13  ? 108.946 123.144 112.624 1.00 45.27  ? 12  GLY c CA  1 
ATOM 2711 C C   . GLY D 3 13  ? 109.173 124.620 112.900 1.00 45.27  ? 12  GLY c C   1 
ATOM 2712 O O   . GLY D 3 13  ? 110.236 125.052 113.347 1.00 45.27  ? 12  GLY c O   1 
ATOM 2713 N N   . LYS D 3 14  ? 108.132 125.401 112.611 1.00 52.08  ? 13  LYS c N   1 
ATOM 2714 C CA  . LYS D 3 14  ? 108.213 126.839 112.838 1.00 52.08  ? 13  LYS c CA  1 
ATOM 2715 C C   . LYS D 3 14  ? 108.305 127.159 114.325 1.00 52.08  ? 13  LYS c C   1 
ATOM 2716 O O   . LYS D 3 14  ? 109.081 128.032 114.731 1.00 52.08  ? 13  LYS c O   1 
ATOM 2717 C CB  . LYS D 3 14  ? 107.010 127.537 112.206 1.00 52.08  ? 13  LYS c CB  1 
ATOM 2718 C CG  . LYS D 3 14  ? 107.031 129.048 112.335 1.00 52.08  ? 13  LYS c CG  1 
ATOM 2719 C CD  . LYS D 3 14  ? 105.868 129.677 111.589 1.00 52.08  ? 13  LYS c CD  1 
ATOM 2720 C CE  . LYS D 3 14  ? 105.800 131.172 111.836 1.00 52.08  ? 13  LYS c CE  1 
ATOM 2721 N NZ  . LYS D 3 14  ? 106.979 131.875 111.261 1.00 52.08  ? 13  LYS c NZ  1 
ATOM 2722 N N   . ASP D 3 15  ? 107.526 126.463 115.151 1.00 54.08  ? 14  ASP c N   1 
ATOM 2723 C CA  . ASP D 3 15  ? 107.562 126.658 116.594 1.00 54.08  ? 14  ASP c CA  1 
ATOM 2724 C C   . ASP D 3 15  ? 108.541 125.731 117.305 1.00 54.08  ? 14  ASP c C   1 
ATOM 2725 O O   . ASP D 3 15  ? 108.769 125.904 118.507 1.00 54.08  ? 14  ASP c O   1 
ATOM 2726 C CB  . ASP D 3 15  ? 106.158 126.483 117.185 1.00 54.08  ? 14  ASP c CB  1 
ATOM 2727 C CG  . ASP D 3 15  ? 105.570 125.114 116.907 1.00 54.08  ? 14  ASP c CG  1 
ATOM 2728 O OD1 . ASP D 3 15  ? 106.216 124.312 116.202 1.00 54.08  ? 14  ASP c OD1 1 
ATOM 2729 O OD2 . ASP D 3 15  ? 104.453 124.840 117.394 1.00 54.08  ? 14  ASP c OD2 1 
ATOM 2730 N N   . GLY D 3 16  ? 109.122 124.764 116.601 1.00 48.64  ? 15  GLY c N   1 
ATOM 2731 C CA  . GLY D 3 16  ? 110.125 123.905 117.199 1.00 48.64  ? 15  GLY c CA  1 
ATOM 2732 C C   . GLY D 3 16  ? 109.596 122.800 118.082 1.00 48.64  ? 15  GLY c C   1 
ATOM 2733 O O   . GLY D 3 16  ? 110.290 122.380 119.014 1.00 48.64  ? 15  GLY c O   1 
ATOM 2734 N N   . LYS D 3 17  ? 108.383 122.311 117.823 1.00 48.40  ? 16  LYS c N   1 
ATOM 2735 C CA  . LYS D 3 17  ? 107.815 121.212 118.589 1.00 48.40  ? 16  LYS c CA  1 
ATOM 2736 C C   . LYS D 3 17  ? 107.513 119.968 117.768 1.00 48.40  ? 16  LYS c C   1 
ATOM 2737 O O   . LYS D 3 17  ? 107.318 118.900 118.357 1.00 48.40  ? 16  LYS c O   1 
ATOM 2738 C CB  . LYS D 3 17  ? 106.522 121.655 119.292 1.00 48.40  ? 16  LYS c CB  1 
ATOM 2739 C CG  . LYS D 3 17  ? 106.745 122.425 120.580 1.00 48.40  ? 16  LYS c CG  1 
ATOM 2740 C CD  . LYS D 3 17  ? 105.545 123.293 120.913 1.00 48.40  ? 16  LYS c CD  1 
ATOM 2741 C CE  . LYS D 3 17  ? 105.718 123.985 122.252 1.00 48.40  ? 16  LYS c CE  1 
ATOM 2742 N NZ  . LYS D 3 17  ? 104.813 125.159 122.388 1.00 48.40  ? 16  LYS c NZ  1 
ATOM 2743 N N   . GLN D 3 18  ? 107.475 120.066 116.443 1.00 47.70  ? 17  GLN c N   1 
ATOM 2744 C CA  . GLN D 3 18  ? 107.111 118.936 115.605 1.00 47.70  ? 17  GLN c CA  1 
ATOM 2745 C C   . GLN D 3 18  ? 108.281 117.964 115.472 1.00 47.70  ? 17  GLN c C   1 
ATOM 2746 O O   . GLN D 3 18  ? 109.376 118.186 115.995 1.00 47.70  ? 17  GLN c O   1 
ATOM 2747 C CB  . GLN D 3 18  ? 106.655 119.419 114.232 1.00 47.70  ? 17  GLN c CB  1 
ATOM 2748 C CG  . GLN D 3 18  ? 105.880 120.719 114.256 1.00 47.70  ? 17  GLN c CG  1 
ATOM 2749 C CD  . GLN D 3 18  ? 105.189 121.001 112.941 1.00 47.70  ? 17  GLN c CD  1 
ATOM 2750 O OE1 . GLN D 3 18  ? 104.466 120.156 112.413 1.00 47.70  ? 17  GLN c OE1 1 
ATOM 2751 N NE2 . GLN D 3 18  ? 105.408 122.194 112.401 1.00 47.70  ? 17  GLN c NE2 1 
ATOM 2752 N N   . THR D 3 19  ? 108.038 116.873 114.750 1.00 48.08  ? 18  THR c N   1 
ATOM 2753 C CA  . THR D 3 19  ? 109.029 115.848 114.451 1.00 48.08  ? 18  THR c CA  1 
ATOM 2754 C C   . THR D 3 19  ? 108.424 114.880 113.448 1.00 48.08  ? 18  THR c C   1 
ATOM 2755 O O   . THR D 3 19  ? 107.199 114.778 113.335 1.00 48.08  ? 18  THR c O   1 
ATOM 2756 C CB  . THR D 3 19  ? 109.469 115.095 115.712 1.00 48.08  ? 18  THR c CB  1 
ATOM 2757 O OG1 . THR D 3 19  ? 110.492 114.152 115.375 1.00 48.08  ? 18  THR c OG1 1 
ATOM 2758 C CG2 . THR D 3 19  ? 108.300 114.360 116.319 1.00 48.08  ? 18  THR c CG2 1 
ATOM 2759 N N   . LEU D 3 20  ? 109.288 114.178 112.718 1.00 45.91  ? 19  LEU c N   1 
ATOM 2760 C CA  . LEU D 3 20  ? 108.843 113.170 111.769 1.00 45.91  ? 19  LEU c CA  1 
ATOM 2761 C C   . LEU D 3 20  ? 109.752 111.954 111.855 1.00 45.91  ? 19  LEU c C   1 
ATOM 2762 O O   . LEU D 3 20  ? 110.936 112.065 112.182 1.00 45.91  ? 19  LEU c O   1 
ATOM 2763 C CB  . LEU D 3 20  ? 108.830 113.687 110.321 1.00 45.91  ? 19  LEU c CB  1 
ATOM 2764 C CG  . LEU D 3 20  ? 110.160 113.846 109.579 1.00 45.91  ? 19  LEU c CG  1 
ATOM 2765 C CD1 . LEU D 3 20  ? 109.914 114.006 108.086 1.00 45.91  ? 19  LEU c CD1 1 
ATOM 2766 C CD2 . LEU D 3 20  ? 110.984 114.995 110.108 1.00 45.91  ? 19  LEU c CD2 1 
ATOM 2767 N N   . VAL D 3 21  ? 109.182 110.791 111.557 1.00 44.36  ? 20  VAL c N   1 
ATOM 2768 C CA  . VAL D 3 21  ? 109.922 109.539 111.471 1.00 44.36  ? 20  VAL c CA  1 
ATOM 2769 C C   . VAL D 3 21  ? 109.811 109.021 110.044 1.00 44.36  ? 20  VAL c C   1 
ATOM 2770 O O   . VAL D 3 21  ? 108.712 108.957 109.482 1.00 44.36  ? 20  VAL c O   1 
ATOM 2771 C CB  . VAL D 3 21  ? 109.420 108.505 112.499 1.00 44.36  ? 20  VAL c CB  1 
ATOM 2772 C CG1 . VAL D 3 21  ? 107.973 108.113 112.238 1.00 44.36  ? 20  VAL c CG1 1 
ATOM 2773 C CG2 . VAL D 3 21  ? 110.305 107.273 112.475 1.00 44.36  ? 20  VAL c CG2 1 
ATOM 2774 N N   . LEU D 3 22  ? 110.952 108.701 109.445 1.00 43.72  ? 21  LEU c N   1 
ATOM 2775 C CA  . LEU D 3 22  ? 111.002 108.226 108.071 1.00 43.72  ? 21  LEU c CA  1 
ATOM 2776 C C   . LEU D 3 22  ? 111.919 107.016 107.985 1.00 43.72  ? 21  LEU c C   1 
ATOM 2777 O O   . LEU D 3 22  ? 112.957 106.963 108.651 1.00 43.72  ? 21  LEU c O   1 
ATOM 2778 C CB  . LEU D 3 22  ? 111.457 109.339 107.111 1.00 43.72  ? 21  LEU c CB  1 
ATOM 2779 C CG  . LEU D 3 22  ? 112.905 109.827 107.086 1.00 43.72  ? 21  LEU c CG  1 
ATOM 2780 C CD1 . LEU D 3 22  ? 113.148 110.624 105.821 1.00 43.72  ? 21  LEU c CD1 1 
ATOM 2781 C CD2 . LEU D 3 22  ? 113.213 110.682 108.297 1.00 43.72  ? 21  LEU c CD2 1 
ATOM 2782 N N   . ASN D 3 23  ? 111.527 106.047 107.161 1.00 45.43  ? 22  ASN c N   1 
ATOM 2783 C CA  . ASN D 3 23  ? 112.170 104.747 107.084 1.00 45.43  ? 22  ASN c CA  1 
ATOM 2784 C C   . ASN D 3 23  ? 112.614 104.435 105.657 1.00 45.43  ? 22  ASN c C   1 
ATOM 2785 O O   . ASN D 3 23  ? 112.043 104.961 104.697 1.00 45.43  ? 22  ASN c O   1 
ATOM 2786 C CB  . ASN D 3 23  ? 111.221 103.654 107.600 1.00 45.43  ? 22  ASN c CB  1 
ATOM 2787 C CG  . ASN D 3 23  ? 109.886 103.644 106.882 1.00 45.43  ? 22  ASN c CG  1 
ATOM 2788 O OD1 . ASN D 3 23  ? 109.673 104.380 105.920 1.00 45.43  ? 22  ASN c OD1 1 
ATOM 2789 N ND2 . ASN D 3 23  ? 108.971 102.808 107.356 1.00 45.43  ? 22  ASN c ND2 1 
ATOM 2790 N N   . PRO D 3 24  ? 113.637 103.599 105.487 1.00 44.08  ? 23  PRO c N   1 
ATOM 2791 C CA  . PRO D 3 24  ? 114.203 103.381 104.151 1.00 44.08  ? 23  PRO c CA  1 
ATOM 2792 C C   . PRO D 3 24  ? 113.239 102.664 103.219 1.00 44.08  ? 23  PRO c C   1 
ATOM 2793 O O   . PRO D 3 24  ? 112.349 101.923 103.639 1.00 44.08  ? 23  PRO c O   1 
ATOM 2794 C CB  . PRO D 3 24  ? 115.440 102.522 104.429 1.00 44.08  ? 23  PRO c CB  1 
ATOM 2795 C CG  . PRO D 3 24  ? 115.127 101.831 105.705 1.00 44.08  ? 23  PRO c CG  1 
ATOM 2796 C CD  . PRO D 3 24  ? 114.367 102.836 106.514 1.00 44.08  ? 23  PRO c CD  1 
ATOM 2797 N N   . ARG D 3 25  ? 113.438 102.901 101.925 1.00 42.75  ? 24  ARG c N   1 
ATOM 2798 C CA  . ARG D 3 25  ? 112.637 102.280 100.875 1.00 42.75  ? 24  ARG c CA  1 
ATOM 2799 C C   . ARG D 3 25  ? 113.539 101.785 99.748  1.00 42.75  ? 24  ARG c C   1 
ATOM 2800 O O   . ARG D 3 25  ? 113.258 101.971 98.564  1.00 42.75  ? 24  ARG c O   1 
ATOM 2801 C CB  . ARG D 3 25  ? 111.579 103.246 100.347 1.00 42.75  ? 24  ARG c CB  1 
ATOM 2802 C CG  . ARG D 3 25  ? 110.446 103.508 101.320 1.00 42.75  ? 24  ARG c CG  1 
ATOM 2803 C CD  . ARG D 3 25  ? 109.092 103.360 100.640 1.00 42.75  ? 24  ARG c CD  1 
ATOM 2804 N NE  . ARG D 3 25  ? 107.997 103.884 101.449 1.00 42.75  ? 24  ARG c NE  1 
ATOM 2805 C CZ  . ARG D 3 25  ? 107.583 103.360 102.595 1.00 42.75  ? 24  ARG c CZ  1 
ATOM 2806 N NH1 . ARG D 3 25  ? 108.138 102.269 103.100 1.00 42.75  ? 24  ARG c NH1 1 
ATOM 2807 N NH2 . ARG D 3 25  ? 106.583 103.941 103.251 1.00 42.75  ? 24  ARG c NH2 1 
ATOM 2808 N N   . GLY D 3 26  ? 114.647 101.146 100.115 1.00 46.86  ? 25  GLY c N   1 
ATOM 2809 C CA  . GLY D 3 26  ? 115.503 100.494 99.146  1.00 46.86  ? 25  GLY c CA  1 
ATOM 2810 C C   . GLY D 3 26  ? 116.396 101.451 98.380  1.00 46.86  ? 25  GLY c C   1 
ATOM 2811 O O   . GLY D 3 26  ? 116.427 102.661 98.608  1.00 46.86  ? 25  GLY c O   1 
ATOM 2812 N N   . VAL D 3 27  ? 117.144 100.875 97.441  1.00 51.58  ? 26  VAL c N   1 
ATOM 2813 C CA  . VAL D 3 27  ? 118.090 101.609 96.610  1.00 51.58  ? 26  VAL c CA  1 
ATOM 2814 C C   . VAL D 3 27  ? 117.840 101.250 95.151  1.00 51.58  ? 26  VAL c C   1 
ATOM 2815 O O   . VAL D 3 27  ? 117.608 100.083 94.819  1.00 51.58  ? 26  VAL c O   1 
ATOM 2816 C CB  . VAL D 3 27  ? 119.551 101.309 97.016  1.00 51.58  ? 26  VAL c CB  1 
ATOM 2817 C CG1 . VAL D 3 27  ? 119.828 99.816  96.976  1.00 51.58  ? 26  VAL c CG1 1 
ATOM 2818 C CG2 . VAL D 3 27  ? 120.524 102.058 96.122  1.00 51.58  ? 26  VAL c CG2 1 
ATOM 2819 N N   . ASN D 3 28  ? 117.867 102.257 94.285  1.00 54.84  ? 27  ASN c N   1 
ATOM 2820 C CA  . ASN D 3 28  ? 117.635 102.036 92.863  1.00 54.84  ? 27  ASN c CA  1 
ATOM 2821 C C   . ASN D 3 28  ? 118.919 101.552 92.200  1.00 54.84  ? 27  ASN c C   1 
ATOM 2822 O O   . ASN D 3 28  ? 119.919 102.277 92.211  1.00 54.84  ? 27  ASN c O   1 
ATOM 2823 C CB  . ASN D 3 28  ? 117.148 103.317 92.200  1.00 54.84  ? 27  ASN c CB  1 
ATOM 2824 C CG  . ASN D 3 28  ? 116.959 103.166 90.704  1.00 54.84  ? 27  ASN c CG  1 
ATOM 2825 O OD1 . ASN D 3 28  ? 116.644 102.084 90.212  1.00 54.84  ? 27  ASN c OD1 1 
ATOM 2826 N ND2 . ASN D 3 28  ? 117.148 104.258 89.972  1.00 54.84  ? 27  ASN c ND2 1 
ATOM 2827 N N   . PRO D 3 29  ? 118.939 100.349 91.620  1.00 56.43  ? 28  PRO c N   1 
ATOM 2828 C CA  . PRO D 3 29  ? 120.182 99.849  91.009  1.00 56.43  ? 28  PRO c CA  1 
ATOM 2829 C C   . PRO D 3 29  ? 120.626 100.625 89.781  1.00 56.43  ? 28  PRO c C   1 
ATOM 2830 O O   . PRO D 3 29  ? 121.807 100.550 89.423  1.00 56.43  ? 28  PRO c O   1 
ATOM 2831 C CB  . PRO D 3 29  ? 119.840 98.395  90.648  1.00 56.43  ? 28  PRO c CB  1 
ATOM 2832 C CG  . PRO D 3 29  ? 118.608 98.068  91.439  1.00 56.43  ? 28  PRO c CG  1 
ATOM 2833 C CD  . PRO D 3 29  ? 117.859 99.352  91.572  1.00 56.43  ? 28  PRO c CD  1 
ATOM 2834 N N   . THR D 3 30  ? 119.725 101.357 89.123  1.00 60.68  ? 29  THR c N   1 
ATOM 2835 C CA  . THR D 3 30  ? 120.081 102.025 87.873  1.00 60.68  ? 29  THR c CA  1 
ATOM 2836 C C   . THR D 3 30  ? 121.128 103.110 88.099  1.00 60.68  ? 29  THR c C   1 
ATOM 2837 O O   . THR D 3 30  ? 122.126 103.184 87.373  1.00 60.68  ? 29  THR c O   1 
ATOM 2838 C CB  . THR D 3 30  ? 118.830 102.611 87.218  1.00 60.68  ? 29  THR c CB  1 
ATOM 2839 O OG1 . THR D 3 30  ? 117.953 101.549 86.823  1.00 60.68  ? 29  THR c OG1 1 
ATOM 2840 C CG2 . THR D 3 30  ? 119.204 103.432 85.993  1.00 60.68  ? 29  THR c CG2 1 
ATOM 2841 N N   . ASN D 3 31  ? 120.923 103.958 89.108  1.00 57.56  ? 30  ASN c N   1 
ATOM 2842 C CA  . ASN D 3 31  ? 121.843 105.048 89.391  1.00 57.56  ? 30  ASN c CA  1 
ATOM 2843 C C   . ASN D 3 31  ? 122.371 105.051 90.818  1.00 57.56  ? 30  ASN c C   1 
ATOM 2844 O O   . ASN D 3 31  ? 123.100 105.979 91.186  1.00 57.56  ? 30  ASN c O   1 
ATOM 2845 C CB  . ASN D 3 31  ? 121.177 106.401 89.094  1.00 57.56  ? 30  ASN c CB  1 
ATOM 2846 C CG  . ASN D 3 31  ? 119.816 106.533 89.742  1.00 57.56  ? 30  ASN c CG  1 
ATOM 2847 O OD1 . ASN D 3 31  ? 119.359 105.632 90.443  1.00 57.56  ? 30  ASN c OD1 1 
ATOM 2848 N ND2 . ASN D 3 31  ? 119.158 107.663 89.511  1.00 57.56  ? 30  ASN c ND2 1 
ATOM 2849 N N   . GLY D 3 32  ? 122.032 104.050 91.627  1.00 55.02  ? 31  GLY c N   1 
ATOM 2850 C CA  . GLY D 3 32  ? 122.554 103.952 92.976  1.00 55.02  ? 31  GLY c CA  1 
ATOM 2851 C C   . GLY D 3 32  ? 122.149 105.088 93.891  1.00 55.02  ? 31  GLY c C   1 
ATOM 2852 O O   . GLY D 3 32  ? 122.990 105.643 94.603  1.00 55.02  ? 31  GLY c O   1 
ATOM 2853 N N   . VAL D 3 33  ? 120.868 105.446 93.885  1.00 48.47  ? 32  VAL c N   1 
ATOM 2854 C CA  . VAL D 3 33  ? 120.345 106.505 94.739  1.00 48.47  ? 32  VAL c CA  1 
ATOM 2855 C C   . VAL D 3 33  ? 119.527 105.875 95.859  1.00 48.47  ? 32  VAL c C   1 
ATOM 2856 O O   . VAL D 3 33  ? 118.682 105.004 95.614  1.00 48.47  ? 32  VAL c O   1 
ATOM 2857 C CB  . VAL D 3 33  ? 119.509 107.517 93.933  1.00 48.47  ? 32  VAL c CB  1 
ATOM 2858 C CG1 . VAL D 3 33  ? 120.374 108.194 92.885  1.00 48.47  ? 32  VAL c CG1 1 
ATOM 2859 C CG2 . VAL D 3 33  ? 118.318 106.847 93.267  1.00 48.47  ? 32  VAL c CG2 1 
ATOM 2860 N N   . ALA D 3 34  ? 119.805 106.283 97.093  1.00 43.20  ? 33  ALA c N   1 
ATOM 2861 C CA  . ALA D 3 34  ? 119.026 105.814 98.225  1.00 43.20  ? 33  ALA c CA  1 
ATOM 2862 C C   . ALA D 3 34  ? 117.679 106.531 98.267  1.00 43.20  ? 33  ALA c C   1 
ATOM 2863 O O   . ALA D 3 34  ? 117.419 107.471 97.511  1.00 43.20  ? 33  ALA c O   1 
ATOM 2864 C CB  . ALA D 3 34  ? 119.789 106.030 99.530  1.00 43.20  ? 33  ALA c CB  1 
ATOM 2865 N N   . SER D 3 35  ? 116.811 106.075 99.165  1.00 41.82  ? 34  SER c N   1 
ATOM 2866 C CA  . SER D 3 35  ? 115.494 106.676 99.301  1.00 41.82  ? 34  SER c CA  1 
ATOM 2867 C C   . SER D 3 35  ? 114.988 106.484 100.721 1.00 41.82  ? 34  SER c C   1 
ATOM 2868 O O   . SER D 3 35  ? 115.320 105.501 101.389 1.00 41.82  ? 34  SER c O   1 
ATOM 2869 C CB  . SER D 3 35  ? 114.492 106.080 98.305  1.00 41.82  ? 34  SER c CB  1 
ATOM 2870 O OG  . SER D 3 35  ? 114.955 106.202 96.973  1.00 41.82  ? 34  SER c OG  1 
ATOM 2871 N N   . LEU D 3 36  ? 114.182 107.440 101.172 1.00 41.94  ? 35  LEU c N   1 
ATOM 2872 C CA  . LEU D 3 36  ? 113.493 107.361 102.449 1.00 41.94  ? 35  LEU c CA  1 
ATOM 2873 C C   . LEU D 3 36  ? 112.128 108.011 102.292 1.00 41.94  ? 35  LEU c C   1 
ATOM 2874 O O   . LEU D 3 36  ? 111.915 108.836 101.403 1.00 41.94  ? 35  LEU c O   1 
ATOM 2875 C CB  . LEU D 3 36  ? 114.282 108.042 103.574 1.00 41.94  ? 35  LEU c CB  1 
ATOM 2876 C CG  . LEU D 3 36  ? 115.625 107.432 103.973 1.00 41.94  ? 35  LEU c CG  1 
ATOM 2877 C CD1 . LEU D 3 36  ? 116.766 108.176 103.305 1.00 41.94  ? 35  LEU c CD1 1 
ATOM 2878 C CD2 . LEU D 3 36  ? 115.789 107.440 105.481 1.00 41.94  ? 35  LEU c CD2 1 
ATOM 2879 N N   . SER D 3 37  ? 111.197 107.628 103.161 1.00 45.38  ? 36  SER c N   1 
ATOM 2880 C CA  . SER D 3 37  ? 109.851 108.174 103.083 1.00 45.38  ? 36  SER c CA  1 
ATOM 2881 C C   . SER D 3 37  ? 109.165 108.019 104.430 1.00 45.38  ? 36  SER c C   1 
ATOM 2882 O O   . SER D 3 37  ? 109.590 107.231 105.279 1.00 45.38  ? 36  SER c O   1 
ATOM 2883 C CB  . SER D 3 37  ? 109.032 107.491 101.984 1.00 45.38  ? 36  SER c CB  1 
ATOM 2884 O OG  . SER D 3 37  ? 108.708 106.164 102.349 1.00 45.38  ? 36  SER c OG  1 
ATOM 2885 N N   . GLN D 3 38  ? 108.092 108.780 104.607 1.00 51.24  ? 37  GLN c N   1 
ATOM 2886 C CA  . GLN D 3 38  ? 107.293 108.754 105.823 1.00 51.24  ? 37  GLN c CA  1 
ATOM 2887 C C   . GLN D 3 38  ? 106.039 107.922 105.597 1.00 51.24  ? 37  GLN c C   1 
ATOM 2888 O O   . GLN D 3 38  ? 105.392 108.027 104.551 1.00 51.24  ? 37  GLN c O   1 
ATOM 2889 C CB  . GLN D 3 38  ? 106.913 110.173 106.248 1.00 51.24  ? 37  GLN c CB  1 
ATOM 2890 C CG  . GLN D 3 38  ? 106.013 110.239 107.464 1.00 51.24  ? 37  GLN c CG  1 
ATOM 2891 C CD  . GLN D 3 38  ? 105.526 111.643 107.746 1.00 51.24  ? 37  GLN c CD  1 
ATOM 2892 O OE1 . GLN D 3 38  ? 105.103 112.358 106.838 1.00 51.24  ? 37  GLN c OE1 1 
ATOM 2893 N NE2 . GLN D 3 38  ? 105.583 112.047 109.009 1.00 51.24  ? 37  GLN c NE2 1 
ATOM 2894 N N   . ALA D 3 39  ? 105.698 107.093 106.581 1.00 60.31  ? 38  ALA c N   1 
ATOM 2895 C CA  . ALA D 3 39  ? 104.538 106.207 106.484 1.00 60.31  ? 38  ALA c CA  1 
ATOM 2896 C C   . ALA D 3 39  ? 103.274 107.043 106.643 1.00 60.31  ? 38  ALA c C   1 
ATOM 2897 O O   . ALA D 3 39  ? 102.759 107.234 107.745 1.00 60.31  ? 38  ALA c O   1 
ATOM 2898 C CB  . ALA D 3 39  ? 104.614 105.104 107.531 1.00 60.31  ? 38  ALA c CB  1 
ATOM 2899 N N   . GLY D 3 40  ? 102.768 107.548 105.521 1.00 64.19  ? 39  GLY c N   1 
ATOM 2900 C CA  . GLY D 3 40  ? 101.597 108.398 105.499 1.00 64.19  ? 39  GLY c CA  1 
ATOM 2901 C C   . GLY D 3 40  ? 100.309 107.737 105.060 1.00 64.19  ? 39  GLY c C   1 
ATOM 2902 O O   . GLY D 3 40  ? 99.335  108.448 104.782 1.00 64.19  ? 39  GLY c O   1 
ATOM 2903 N N   . ALA D 3 41  ? 100.275 106.407 104.963 1.00 62.91  ? 40  ALA c N   1 
ATOM 2904 C CA  . ALA D 3 41  ? 99.117  105.590 104.608 1.00 62.91  ? 40  ALA c CA  1 
ATOM 2905 C C   . ALA D 3 41  ? 98.670  105.771 103.162 1.00 62.91  ? 40  ALA c C   1 
ATOM 2906 O O   . ALA D 3 41  ? 97.763  105.058 102.720 1.00 62.91  ? 40  ALA c O   1 
ATOM 2907 C CB  . ALA D 3 41  ? 97.914  105.841 105.531 1.00 62.91  ? 40  ALA c CB  1 
ATOM 2908 N N   . VAL D 3 42  ? 99.270  106.689 102.410 1.00 59.72  ? 41  VAL c N   1 
ATOM 2909 C CA  . VAL D 3 42  ? 98.986  106.847 100.986 1.00 59.72  ? 41  VAL c CA  1 
ATOM 2910 C C   . VAL D 3 42  ? 100.312 107.081 100.272 1.00 59.72  ? 41  VAL c C   1 
ATOM 2911 O O   . VAL D 3 42  ? 101.057 108.002 100.637 1.00 59.72  ? 41  VAL c O   1 
ATOM 2912 C CB  . VAL D 3 42  ? 97.997  107.994 100.725 1.00 59.72  ? 41  VAL c CB  1 
ATOM 2913 C CG1 . VAL D 3 42  ? 98.060  108.421 99.271  1.00 59.72  ? 41  VAL c CG1 1 
ATOM 2914 C CG2 . VAL D 3 42  ? 96.584  107.573 101.090 1.00 59.72  ? 41  VAL c CG2 1 
ATOM 2915 N N   . PRO D 3 43  ? 100.653 106.274 99.265  1.00 54.23  ? 42  PRO c N   1 
ATOM 2916 C CA  . PRO D 3 43  ? 101.985 106.387 98.649  1.00 54.23  ? 42  PRO c CA  1 
ATOM 2917 C C   . PRO D 3 43  ? 102.255 107.719 97.970  1.00 54.23  ? 42  PRO c C   1 
ATOM 2918 O O   . PRO D 3 43  ? 103.426 108.090 97.823  1.00 54.23  ? 42  PRO c O   1 
ATOM 2919 C CB  . PRO D 3 43  ? 102.000 105.234 97.635  1.00 54.23  ? 42  PRO c CB  1 
ATOM 2920 C CG  . PRO D 3 43  ? 100.935 104.294 98.102  1.00 54.23  ? 42  PRO c CG  1 
ATOM 2921 C CD  . PRO D 3 43  ? 99.877  105.158 98.706  1.00 54.23  ? 42  PRO c CD  1 
ATOM 2922 N N   . ALA D 3 44  ? 101.225 108.451 97.548  1.00 55.07  ? 43  ALA c N   1 
ATOM 2923 C CA  . ALA D 3 44  ? 101.420 109.668 96.771  1.00 55.07  ? 43  ALA c CA  1 
ATOM 2924 C C   . ALA D 3 44  ? 101.436 110.939 97.610  1.00 55.07  ? 43  ALA c C   1 
ATOM 2925 O O   . ALA D 3 44  ? 101.703 112.014 97.062  1.00 55.07  ? 43  ALA c O   1 
ATOM 2926 C CB  . ALA D 3 44  ? 100.334 109.788 95.697  1.00 55.07  ? 43  ALA c CB  1 
ATOM 2927 N N   . LEU D 3 45  ? 101.162 110.854 98.910  1.00 60.14  ? 44  LEU c N   1 
ATOM 2928 C CA  . LEU D 3 45  ? 101.124 112.047 99.749  1.00 60.14  ? 44  LEU c CA  1 
ATOM 2929 C C   . LEU D 3 45  ? 102.076 111.929 100.932 1.00 60.14  ? 44  LEU c C   1 
ATOM 2930 O O   . LEU D 3 45  ? 101.706 112.254 102.064 1.00 60.14  ? 44  LEU c O   1 
ATOM 2931 C CB  . LEU D 3 45  ? 99.703  112.310 100.252 1.00 60.14  ? 44  LEU c CB  1 
ATOM 2932 C CG  . LEU D 3 45  ? 98.546  112.086 99.279  1.00 60.14  ? 44  LEU c CG  1 
ATOM 2933 C CD1 . LEU D 3 45  ? 97.217  112.307 99.980  1.00 60.14  ? 44  LEU c CD1 1 
ATOM 2934 C CD2 . LEU D 3 45  ? 98.672  113.003 98.079  1.00 60.14  ? 44  LEU c CD2 1 
ATOM 2935 N N   . GLU D 3 46  ? 103.299 111.469 100.686 1.00 56.24  ? 45  GLU c N   1 
ATOM 2936 C CA  . GLU D 3 46  ? 104.283 111.284 101.741 1.00 56.24  ? 45  GLU c CA  1 
ATOM 2937 C C   . GLU D 3 46  ? 105.570 112.012 101.384 1.00 56.24  ? 45  GLU c C   1 
ATOM 2938 O O   . GLU D 3 46  ? 106.010 111.987 100.231 1.00 56.24  ? 45  GLU c O   1 
ATOM 2939 C CB  . GLU D 3 46  ? 104.573 109.799 101.973 1.00 56.24  ? 45  GLU c CB  1 
ATOM 2940 C CG  . GLU D 3 46  ? 104.759 109.002 100.695 1.00 56.24  ? 45  GLU c CG  1 
ATOM 2941 C CD  . GLU D 3 46  ? 105.174 107.568 100.956 1.00 56.24  ? 45  GLU c CD  1 
ATOM 2942 O OE1 . GLU D 3 46  ? 104.704 106.983 101.955 1.00 56.24  ? 45  GLU c OE1 1 
ATOM 2943 O OE2 . GLU D 3 46  ? 105.973 107.027 100.163 1.00 56.24  ? 45  GLU c OE2 1 
ATOM 2944 N N   . LYS D 3 47  ? 106.164 112.664 102.379 1.00 48.32  ? 46  LYS c N   1 
ATOM 2945 C CA  . LYS D 3 47  ? 107.450 113.319 102.187 1.00 48.32  ? 46  LYS c CA  1 
ATOM 2946 C C   . LYS D 3 47  ? 108.539 112.279 101.964 1.00 48.32  ? 46  LYS c C   1 
ATOM 2947 O O   . LYS D 3 47  ? 108.554 111.226 102.606 1.00 48.32  ? 46  LYS c O   1 
ATOM 2948 C CB  . LYS D 3 47  ? 107.787 114.182 103.400 1.00 48.32  ? 46  LYS c CB  1 
ATOM 2949 C CG  . LYS D 3 47  ? 106.581 114.856 104.028 1.00 48.32  ? 46  LYS c CG  1 
ATOM 2950 C CD  . LYS D 3 47  ? 106.983 115.721 105.208 1.00 48.32  ? 46  LYS c CD  1 
ATOM 2951 C CE  . LYS D 3 47  ? 105.811 116.545 105.710 1.00 48.32  ? 46  LYS c CE  1 
ATOM 2952 N NZ  . LYS D 3 47  ? 104.725 115.686 106.253 1.00 48.32  ? 46  LYS c NZ  1 
ATOM 2953 N N   . ARG D 3 48  ? 109.459 112.574 101.048 1.00 42.72  ? 47  ARG c N   1 
ATOM 2954 C CA  . ARG D 3 48  ? 110.510 111.629 100.705 1.00 42.72  ? 47  ARG c CA  1 
ATOM 2955 C C   . ARG D 3 48  ? 111.840 112.353 100.562 1.00 42.72  ? 47  ARG c C   1 
ATOM 2956 O O   . ARG D 3 48  ? 111.888 113.543 100.244 1.00 42.72  ? 47  ARG c O   1 
ATOM 2957 C CB  . ARG D 3 48  ? 110.179 110.871 99.415  1.00 42.72  ? 47  ARG c CB  1 
ATOM 2958 C CG  . ARG D 3 48  ? 110.044 111.749 98.188  1.00 42.72  ? 47  ARG c CG  1 
ATOM 2959 C CD  . ARG D 3 48  ? 109.492 110.966 97.006  1.00 42.72  ? 47  ARG c CD  1 
ATOM 2960 N NE  . ARG D 3 48  ? 108.206 110.346 97.305  1.00 42.72  ? 47  ARG c NE  1 
ATOM 2961 C CZ  . ARG D 3 48  ? 108.038 109.059 97.577  1.00 42.72  ? 47  ARG c CZ  1 
ATOM 2962 N NH1 . ARG D 3 48  ? 109.059 108.218 97.600  1.00 42.72  ? 47  ARG c NH1 1 
ATOM 2963 N NH2 . ARG D 3 48  ? 106.815 108.604 97.835  1.00 42.72  ? 47  ARG c NH2 1 
ATOM 2964 N N   . VAL D 3 49  ? 112.920 111.615 100.810 1.00 37.09  ? 48  VAL c N   1 
ATOM 2965 C CA  . VAL D 3 49  ? 114.282 112.131 100.727 1.00 37.09  ? 48  VAL c CA  1 
ATOM 2966 C C   . VAL D 3 49  ? 115.131 111.127 99.963  1.00 37.09  ? 48  VAL c C   1 
ATOM 2967 O O   . VAL D 3 49  ? 115.034 109.917 100.193 1.00 37.09  ? 48  VAL c O   1 
ATOM 2968 C CB  . VAL D 3 49  ? 114.884 112.390 102.124 1.00 37.09  ? 48  VAL c CB  1 
ATOM 2969 C CG1 . VAL D 3 49  ? 116.246 113.048 102.001 1.00 37.09  ? 48  VAL c CG1 1 
ATOM 2970 C CG2 . VAL D 3 49  ? 113.953 113.244 102.967 1.00 37.09  ? 48  VAL c CG2 1 
ATOM 2971 N N   . THR D 3 50  ? 115.965 111.624 99.052  1.00 35.30  ? 49  THR c N   1 
ATOM 2972 C CA  . THR D 3 50  ? 116.877 110.785 98.285  1.00 35.30  ? 49  THR c CA  1 
ATOM 2973 C C   . THR D 3 50  ? 118.288 111.339 98.408  1.00 35.30  ? 49  THR c C   1 
ATOM 2974 O O   . THR D 3 50  ? 118.515 112.525 98.152  1.00 35.30  ? 49  THR c O   1 
ATOM 2975 C CB  . THR D 3 50  ? 116.472 110.712 96.809  1.00 35.30  ? 49  THR c CB  1 
ATOM 2976 O OG1 . THR D 3 50  ? 116.597 112.008 96.212  1.00 35.30  ? 49  THR c OG1 1 
ATOM 2977 C CG2 . THR D 3 50  ? 115.036 110.231 96.667  1.00 35.30  ? 49  THR c CG2 1 
ATOM 2978 N N   . VAL D 3 51  ? 119.230 110.481 98.791  1.00 37.01  ? 50  VAL c N   1 
ATOM 2979 C CA  . VAL D 3 51  ? 120.627 110.859 98.958  1.00 37.01  ? 50  VAL c CA  1 
ATOM 2980 C C   . VAL D 3 51  ? 121.494 109.900 98.153  1.00 37.01  ? 50  VAL c C   1 
ATOM 2981 O O   . VAL D 3 51  ? 121.252 108.688 98.142  1.00 37.01  ? 50  VAL c O   1 
ATOM 2982 C CB  . VAL D 3 51  ? 121.040 110.871 100.447 1.00 37.01  ? 50  VAL c CB  1 
ATOM 2983 C CG1 . VAL D 3 51  ? 120.832 109.507 101.081 1.00 37.01  ? 50  VAL c CG1 1 
ATOM 2984 C CG2 . VAL D 3 51  ? 122.486 111.315 100.598 1.00 37.01  ? 50  VAL c CG2 1 
ATOM 2985 N N   . SER D 3 52  ? 122.490 110.446 97.459  1.00 41.64  ? 51  SER c N   1 
ATOM 2986 C CA  . SER D 3 52  ? 123.378 109.639 96.636  1.00 41.64  ? 51  SER c CA  1 
ATOM 2987 C C   . SER D 3 52  ? 124.743 110.303 96.554  1.00 41.64  ? 51  SER c C   1 
ATOM 2988 O O   . SER D 3 52  ? 124.838 111.527 96.442  1.00 41.64  ? 51  SER c O   1 
ATOM 2989 C CB  . SER D 3 52  ? 122.811 109.445 95.227  1.00 41.64  ? 51  SER c CB  1 
ATOM 2990 O OG  . SER D 3 52  ? 123.159 110.531 94.388  1.00 41.64  ? 51  SER c OG  1 
ATOM 2991 N N   . VAL D 3 53  ? 125.792 109.486 96.607  1.00 46.06  ? 52  VAL c N   1 
ATOM 2992 C CA  . VAL D 3 53  ? 127.168 109.942 96.456  1.00 46.06  ? 52  VAL c CA  1 
ATOM 2993 C C   . VAL D 3 53  ? 127.780 109.219 95.263  1.00 46.06  ? 52  VAL c C   1 
ATOM 2994 O O   . VAL D 3 53  ? 127.648 107.997 95.134  1.00 46.06  ? 52  VAL c O   1 
ATOM 2995 C CB  . VAL D 3 53  ? 127.991 109.712 97.739  1.00 46.06  ? 52  VAL c CB  1 
ATOM 2996 C CG1 . VAL D 3 53  ? 127.932 108.263 98.165  1.00 46.06  ? 52  VAL c CG1 1 
ATOM 2997 C CG2 . VAL D 3 53  ? 129.432 110.142 97.528  1.00 46.06  ? 52  VAL c CG2 1 
ATOM 2998 N N   . SER D 3 54  ? 128.426 109.977 94.383  1.00 54.29  ? 53  SER c N   1 
ATOM 2999 C CA  . SER D 3 54  ? 128.942 109.438 93.135  1.00 54.29  ? 53  SER c CA  1 
ATOM 3000 C C   . SER D 3 54  ? 130.395 108.996 93.311  1.00 54.29  ? 53  SER c C   1 
ATOM 3001 O O   . SER D 3 54  ? 130.943 109.000 94.416  1.00 54.29  ? 53  SER c O   1 
ATOM 3002 C CB  . SER D 3 54  ? 128.795 110.470 92.019  1.00 54.29  ? 53  SER c CB  1 
ATOM 3003 O OG  . SER D 3 54  ? 129.603 110.136 90.905  1.00 54.29  ? 53  SER c OG  1 
ATOM 3004 N N   . GLN D 3 55  ? 131.028 108.602 92.211  1.00 66.79  ? 54  GLN c N   1 
ATOM 3005 C CA  . GLN D 3 55  ? 132.416 108.170 92.176  1.00 66.79  ? 54  GLN c CA  1 
ATOM 3006 C C   . GLN D 3 55  ? 133.097 108.807 90.976  1.00 66.79  ? 54  GLN c C   1 
ATOM 3007 O O   . GLN D 3 55  ? 132.437 109.106 89.973  1.00 66.79  ? 54  GLN c O   1 
ATOM 3008 C CB  . GLN D 3 55  ? 132.530 106.638 92.085  1.00 66.79  ? 54  GLN c CB  1 
ATOM 3009 C CG  . GLN D 3 55  ? 131.814 105.885 93.196  1.00 66.79  ? 54  GLN c CG  1 
ATOM 3010 C CD  . GLN D 3 55  ? 132.722 105.573 94.368  1.00 66.79  ? 54  GLN c CD  1 
ATOM 3011 O OE1 . GLN D 3 55  ? 133.869 105.165 94.189  1.00 66.79  ? 54  GLN c OE1 1 
ATOM 3012 N NE2 . GLN D 3 55  ? 132.211 105.765 95.578  1.00 66.79  ? 54  GLN c NE2 1 
ATOM 3013 N N   . PRO D 3 56  ? 134.419 109.029 91.044  1.00 68.60  ? 55  PRO c N   1 
ATOM 3014 C CA  . PRO D 3 56  ? 135.132 109.631 89.913  1.00 68.60  ? 55  PRO c CA  1 
ATOM 3015 C C   . PRO D 3 56  ? 135.253 108.683 88.725  1.00 68.60  ? 55  PRO c C   1 
ATOM 3016 O O   . PRO D 3 56  ? 135.941 109.018 87.762  1.00 68.60  ? 55  PRO c O   1 
ATOM 3017 C CB  . PRO D 3 56  ? 136.511 109.947 90.498  1.00 68.60  ? 55  PRO c CB  1 
ATOM 3018 C CG  . PRO D 3 56  ? 136.681 108.961 91.595  1.00 68.60  ? 55  PRO c CG  1 
ATOM 3019 C CD  . PRO D 3 56  ? 135.314 108.779 92.187  1.00 68.60  ? 55  PRO c CD  1 
ATOM 3020 N N   . LYS D 3 61  ? 136.987 114.422 87.464  1.00 67.67  ? 60  LYS c N   1 
ATOM 3021 C CA  . LYS D 3 61  ? 137.573 113.413 88.338  1.00 67.67  ? 60  LYS c CA  1 
ATOM 3022 C C   . LYS D 3 61  ? 137.473 113.842 89.798  1.00 67.67  ? 60  LYS c C   1 
ATOM 3023 O O   . LYS D 3 61  ? 138.464 113.840 90.529  1.00 67.67  ? 60  LYS c O   1 
ATOM 3024 C CB  . LYS D 3 61  ? 139.033 113.154 87.957  1.00 67.67  ? 60  LYS c CB  1 
ATOM 3025 C CG  . LYS D 3 61  ? 139.550 111.783 88.362  1.00 67.67  ? 60  LYS c CG  1 
ATOM 3026 C CD  . LYS D 3 61  ? 138.893 110.682 87.547  1.00 67.67  ? 60  LYS c CD  1 
ATOM 3027 C CE  . LYS D 3 61  ? 139.613 109.354 87.726  1.00 67.67  ? 60  LYS c CE  1 
ATOM 3028 N NZ  . LYS D 3 61  ? 139.462 108.816 89.106  1.00 67.67  ? 60  LYS c NZ  1 
ATOM 3029 N N   . ASN D 3 62  ? 136.266 114.213 90.217  1.00 60.49  ? 61  ASN c N   1 
ATOM 3030 C CA  . ASN D 3 62  ? 136.016 114.633 91.586  1.00 60.49  ? 61  ASN c CA  1 
ATOM 3031 C C   . ASN D 3 62  ? 134.686 114.059 92.051  1.00 60.49  ? 61  ASN c C   1 
ATOM 3032 O O   . ASN D 3 62  ? 133.788 113.789 91.251  1.00 60.49  ? 61  ASN c O   1 
ATOM 3033 C CB  . ASN D 3 62  ? 136.019 116.161 91.714  1.00 60.49  ? 61  ASN c CB  1 
ATOM 3034 C CG  . ASN D 3 62  ? 135.258 116.839 90.596  1.00 60.49  ? 61  ASN c CG  1 
ATOM 3035 O OD1 . ASN D 3 62  ? 135.517 116.596 89.418  1.00 60.49  ? 61  ASN c OD1 1 
ATOM 3036 N ND2 . ASN D 3 62  ? 134.315 117.701 90.959  1.00 60.49  ? 61  ASN c ND2 1 
ATOM 3037 N N   . TYR D 3 63  ? 134.573 113.876 93.363  1.00 53.33  ? 62  TYR c N   1 
ATOM 3038 C CA  . TYR D 3 63  ? 133.383 113.274 93.941  1.00 53.33  ? 62  TYR c CA  1 
ATOM 3039 C C   . TYR D 3 63  ? 132.226 114.270 93.940  1.00 53.33  ? 62  TYR c C   1 
ATOM 3040 O O   . TYR D 3 63  ? 132.400 115.472 93.726  1.00 53.33  ? 62  TYR c O   1 
ATOM 3041 C CB  . TYR D 3 63  ? 133.671 112.784 95.359  1.00 53.33  ? 62  TYR c CB  1 
ATOM 3042 C CG  . TYR D 3 63  ? 134.639 111.625 95.414  1.00 53.33  ? 62  TYR c CG  1 
ATOM 3043 C CD1 . TYR D 3 63  ? 136.002 111.823 95.248  1.00 53.33  ? 62  TYR c CD1 1 
ATOM 3044 C CD2 . TYR D 3 63  ? 134.189 110.331 95.629  1.00 53.33  ? 62  TYR c CD2 1 
ATOM 3045 C CE1 . TYR D 3 63  ? 136.888 110.767 95.295  1.00 53.33  ? 62  TYR c CE1 1 
ATOM 3046 C CE2 . TYR D 3 63  ? 135.068 109.269 95.679  1.00 53.33  ? 62  TYR c CE2 1 
ATOM 3047 C CZ  . TYR D 3 63  ? 136.415 109.493 95.511  1.00 53.33  ? 62  TYR c CZ  1 
ATOM 3048 O OH  . TYR D 3 63  ? 137.296 108.437 95.559  1.00 53.33  ? 62  TYR c OH  1 
ATOM 3049 N N   . LYS D 3 64  ? 131.024 113.752 94.182  1.00 49.81  ? 63  LYS c N   1 
ATOM 3050 C CA  . LYS D 3 64  ? 129.822 114.581 94.152  1.00 49.81  ? 63  LYS c CA  1 
ATOM 3051 C C   . LYS D 3 64  ? 128.748 113.925 95.001  1.00 49.81  ? 63  LYS c C   1 
ATOM 3052 O O   . LYS D 3 64  ? 128.338 112.796 94.715  1.00 49.81  ? 63  LYS c O   1 
ATOM 3053 C CB  . LYS D 3 64  ? 129.335 114.774 92.718  1.00 49.81  ? 63  LYS c CB  1 
ATOM 3054 C CG  . LYS D 3 64  ? 128.013 115.510 92.606  1.00 49.81  ? 63  LYS c CG  1 
ATOM 3055 C CD  . LYS D 3 64  ? 127.621 115.713 91.153  1.00 49.81  ? 63  LYS c CD  1 
ATOM 3056 C CE  . LYS D 3 64  ? 128.717 116.429 90.383  1.00 49.81  ? 63  LYS c CE  1 
ATOM 3057 N NZ  . LYS D 3 64  ? 129.155 117.677 91.067  1.00 49.81  ? 63  LYS c NZ  1 
ATOM 3058 N N   . VAL D 3 65  ? 128.293 114.627 96.035  1.00 59.40  ? 64  VAL c N   1 
ATOM 3059 C CA  . VAL D 3 65  ? 127.224 114.165 96.912  1.00 59.40  ? 64  VAL c CA  1 
ATOM 3060 C C   . VAL D 3 65  ? 125.994 115.017 96.642  1.00 59.40  ? 64  VAL c C   1 
ATOM 3061 O O   . VAL D 3 65  ? 126.093 116.246 96.560  1.00 59.40  ? 64  VAL c O   1 
ATOM 3062 C CB  . VAL D 3 65  ? 127.633 114.247 98.392  1.00 59.40  ? 64  VAL c CB  1 
ATOM 3063 C CG1 . VAL D 3 65  ? 126.597 113.566 99.268  1.00 59.40  ? 64  VAL c CG1 1 
ATOM 3064 C CG2 . VAL D 3 65  ? 129.006 113.634 98.599  1.00 59.40  ? 64  VAL c CG2 1 
ATOM 3065 N N   . GLN D 3 66  ? 124.840 114.371 96.498  1.00 39.73  ? 65  GLN c N   1 
ATOM 3066 C CA  . GLN D 3 66  ? 123.602 115.062 96.168  1.00 39.73  ? 65  GLN c CA  1 
ATOM 3067 C C   . GLN D 3 66  ? 122.493 114.629 97.115  1.00 39.73  ? 65  GLN c C   1 
ATOM 3068 O O   . GLN D 3 66  ? 122.348 113.440 97.412  1.00 39.73  ? 65  GLN c O   1 
ATOM 3069 C CB  . GLN D 3 66  ? 123.190 114.786 94.721  1.00 39.73  ? 65  GLN c CB  1 
ATOM 3070 C CG  . GLN D 3 66  ? 122.003 115.600 94.250  1.00 39.73  ? 65  GLN c CG  1 
ATOM 3071 C CD  . GLN D 3 66  ? 122.141 116.043 92.810  1.00 39.73  ? 65  GLN c CD  1 
ATOM 3072 O OE1 . GLN D 3 66  ? 123.029 115.585 92.092  1.00 39.73  ? 65  GLN c OE1 1 
ATOM 3073 N NE2 . GLN D 3 66  ? 121.261 116.939 92.379  1.00 39.73  ? 65  GLN c NE2 1 
ATOM 3074 N N   . VAL D 3 67  ? 121.714 115.600 97.588  1.00 33.06  ? 66  VAL c N   1 
ATOM 3075 C CA  . VAL D 3 67  ? 120.589 115.355 98.482  1.00 33.06  ? 66  VAL c CA  1 
ATOM 3076 C C   . VAL D 3 67  ? 119.381 116.111 97.950  1.00 33.06  ? 66  VAL c C   1 
ATOM 3077 O O   . VAL D 3 67  ? 119.479 117.304 97.644  1.00 33.06  ? 66  VAL c O   1 
ATOM 3078 C CB  . VAL D 3 67  ? 120.899 115.787 99.928  1.00 33.06  ? 66  VAL c CB  1 
ATOM 3079 C CG1 . VAL D 3 67  ? 119.680 115.600 100.811 1.00 33.06  ? 66  VAL c CG1 1 
ATOM 3080 C CG2 . VAL D 3 67  ? 122.081 115.011 100.476 1.00 33.06  ? 66  VAL c CG2 1 
ATOM 3081 N N   . LYS D 3 68  ? 118.246 115.424 97.842  1.00 34.94  ? 67  LYS c N   1 
ATOM 3082 C CA  . LYS D 3 68  ? 117.010 116.026 97.364  1.00 34.94  ? 67  LYS c CA  1 
ATOM 3083 C C   . LYS D 3 68  ? 115.902 115.812 98.383  1.00 34.94  ? 67  LYS c C   1 
ATOM 3084 O O   . LYS D 3 68  ? 115.753 114.717 98.931  1.00 34.94  ? 67  LYS c O   1 
ATOM 3085 C CB  . LYS D 3 68  ? 116.587 115.442 96.014  1.00 34.94  ? 67  LYS c CB  1 
ATOM 3086 C CG  . LYS D 3 68  ? 117.620 115.600 94.917  1.00 34.94  ? 67  LYS c CG  1 
ATOM 3087 C CD  . LYS D 3 68  ? 116.960 115.679 93.554  1.00 34.94  ? 67  LYS c CD  1 
ATOM 3088 C CE  . LYS D 3 68  ? 117.972 116.006 92.470  1.00 34.94  ? 67  LYS c CE  1 
ATOM 3089 N NZ  . LYS D 3 68  ? 117.310 116.398 91.196  1.00 34.94  ? 67  LYS c NZ  1 
ATOM 3090 N N   . ILE D 3 69  ? 115.128 116.865 98.633  1.00 35.44  ? 68  ILE c N   1 
ATOM 3091 C CA  . ILE D 3 69  ? 114.000 116.823 99.556  1.00 35.44  ? 68  ILE c CA  1 
ATOM 3092 C C   . ILE D 3 69  ? 112.784 117.397 98.848  1.00 35.44  ? 68  ILE c C   1 
ATOM 3093 O O   . ILE D 3 69  ? 112.859 118.482 98.262  1.00 35.44  ? 68  ILE c O   1 
ATOM 3094 C CB  . ILE D 3 69  ? 114.288 117.607 100.850 1.00 35.44  ? 68  ILE c CB  1 
ATOM 3095 C CG1 . ILE D 3 69  ? 115.406 116.938 101.645 1.00 35.44  ? 68  ILE c CG1 1 
ATOM 3096 C CG2 . ILE D 3 69  ? 113.032 117.721 101.696 1.00 35.44  ? 68  ILE c CG2 1 
ATOM 3097 C CD1 . ILE D 3 69  ? 115.834 117.720 102.861 1.00 35.44  ? 68  ILE c CD1 1 
ATOM 3098 N N   . GLN D 3 70  ? 111.669 116.674 98.899  1.00 42.10  ? 69  GLN c N   1 
ATOM 3099 C CA  . GLN D 3 70  ? 110.422 117.160 98.329  1.00 42.10  ? 69  GLN c CA  1 
ATOM 3100 C C   . GLN D 3 70  ? 109.259 116.601 99.132  1.00 42.10  ? 69  GLN c C   1 
ATOM 3101 O O   . GLN D 3 70  ? 109.315 115.466 99.611  1.00 42.10  ? 69  GLN c O   1 
ATOM 3102 C CB  . GLN D 3 70  ? 110.292 116.777 96.850  1.00 42.10  ? 69  GLN c CB  1 
ATOM 3103 C CG  . GLN D 3 70  ? 110.100 115.296 96.594  1.00 42.10  ? 69  GLN c CG  1 
ATOM 3104 C CD  . GLN D 3 70  ? 109.439 115.023 95.260  1.00 42.10  ? 69  GLN c CD  1 
ATOM 3105 O OE1 . GLN D 3 70  ? 109.866 115.536 94.226  1.00 42.10  ? 69  GLN c OE1 1 
ATOM 3106 N NE2 . GLN D 3 70  ? 108.388 114.211 95.275  1.00 42.10  ? 69  GLN c NE2 1 
ATOM 3107 N N   . ASN D 3 71  ? 108.211 117.412 99.286  1.00 46.14  ? 70  ASN c N   1 
ATOM 3108 C CA  . ASN D 3 71  ? 107.032 117.004 100.025 1.00 46.14  ? 70  ASN c CA  1 
ATOM 3109 C C   . ASN D 3 71  ? 105.787 117.680 99.466  1.00 46.14  ? 70  ASN c C   1 
ATOM 3110 O O   . ASN D 3 71  ? 105.788 118.908 99.290  1.00 46.14  ? 70  ASN c O   1 
ATOM 3111 C CB  . ASN D 3 71  ? 107.176 117.310 101.517 1.00 46.14  ? 70  ASN c CB  1 
ATOM 3112 C CG  . ASN D 3 71  ? 107.637 118.726 101.786 1.00 46.14  ? 70  ASN c CG  1 
ATOM 3113 O OD1 . ASN D 3 71  ? 107.842 119.514 100.866 1.00 46.14  ? 70  ASN c OD1 1 
ATOM 3114 N ND2 . ASN D 3 71  ? 107.803 119.058 103.061 1.00 46.14  ? 70  ASN c ND2 1 
ATOM 3115 N N   . PRO D 3 72  ? 104.735 116.925 99.169  1.00 54.75  ? 71  PRO c N   1 
ATOM 3116 C CA  . PRO D 3 72  ? 103.539 117.509 98.564  1.00 54.75  ? 71  PRO c CA  1 
ATOM 3117 C C   . PRO D 3 72  ? 102.490 117.906 99.594  1.00 54.75  ? 71  PRO c C   1 
ATOM 3118 O O   . PRO D 3 72  ? 102.529 117.507 100.759 1.00 54.75  ? 71  PRO c O   1 
ATOM 3119 C CB  . PRO D 3 72  ? 103.020 116.372 97.673  1.00 54.75  ? 71  PRO c CB  1 
ATOM 3120 C CG  . PRO D 3 72  ? 103.509 115.111 98.339  1.00 54.75  ? 71  PRO c CG  1 
ATOM 3121 C CD  . PRO D 3 72  ? 104.632 115.462 99.288  1.00 54.75  ? 71  PRO c CD  1 
ATOM 3122 N N   . THR D 3 73  ? 101.539 118.712 99.129  1.00 67.21  ? 72  THR c N   1 
ATOM 3123 C CA  . THR D 3 73  ? 100.398 119.145 99.923  1.00 67.21  ? 72  THR c CA  1 
ATOM 3124 C C   . THR D 3 73  ? 99.123  118.658 99.251  1.00 67.21  ? 72  THR c C   1 
ATOM 3125 O O   . THR D 3 73  ? 98.945  118.843 98.043  1.00 67.21  ? 72  THR c O   1 
ATOM 3126 C CB  . THR D 3 73  ? 100.372 120.668 100.072 1.00 67.21  ? 72  THR c CB  1 
ATOM 3127 O OG1 . THR D 3 73  ? 101.571 121.105 100.724 1.00 67.21  ? 72  THR c OG1 1 
ATOM 3128 C CG2 . THR D 3 73  ? 99.170  121.104 100.893 1.00 67.21  ? 72  THR c CG2 1 
ATOM 3129 N N   . ALA D 3 74  ? 98.242  118.040 100.030 1.00 78.41  ? 73  ALA c N   1 
ATOM 3130 C CA  . ALA D 3 74  ? 97.029  117.435 99.505  1.00 78.41  ? 73  ALA c CA  1 
ATOM 3131 C C   . ALA D 3 74  ? 95.812  118.297 99.816  1.00 78.41  ? 73  ALA c C   1 
ATOM 3132 O O   . ALA D 3 74  ? 95.715  118.910 100.882 1.00 78.41  ? 73  ALA c O   1 
ATOM 3133 C CB  . ALA D 3 74  ? 96.828  116.032 100.080 1.00 78.41  ? 73  ALA c CB  1 
ATOM 3134 N N   . CYS D 3 75  ? 94.879  118.333 98.867  1.00 99.24  ? 74  CYS c N   1 
ATOM 3135 C CA  . CYS D 3 75  ? 93.628  119.059 99.036  1.00 99.24  ? 74  CYS c CA  1 
ATOM 3136 C C   . CYS D 3 75  ? 92.511  118.257 98.389  1.00 99.24  ? 74  CYS c C   1 
ATOM 3137 O O   . CYS D 3 75  ? 92.643  117.822 97.241  1.00 99.24  ? 74  CYS c O   1 
ATOM 3138 C CB  . CYS D 3 75  ? 93.707  120.459 98.419  1.00 99.24  ? 74  CYS c CB  1 
ATOM 3139 S SG  . CYS D 3 75  ? 92.486  121.627 99.062  1.00 99.24  ? 74  CYS c SG  1 
ATOM 3140 N N   . THR D 3 76  ? 91.417  118.066 99.123  1.00 117.09 ? 75  THR c N   1 
ATOM 3141 C CA  . THR D 3 76  ? 90.282  117.268 98.660  1.00 117.09 ? 75  THR c CA  1 
ATOM 3142 C C   . THR D 3 76  ? 89.242  118.216 98.074  1.00 117.09 ? 75  THR c C   1 
ATOM 3143 O O   . THR D 3 76  ? 88.353  118.705 98.772  1.00 117.09 ? 75  THR c O   1 
ATOM 3144 C CB  . THR D 3 76  ? 89.704  116.432 99.796  1.00 117.09 ? 75  THR c CB  1 
ATOM 3145 O OG1 . THR D 3 76  ? 89.130  117.298 100.783 1.00 117.09 ? 75  THR c OG1 1 
ATOM 3146 C CG2 . THR D 3 76  ? 90.792  115.589 100.443 1.00 117.09 ? 75  THR c CG2 1 
ATOM 3147 N N   . ALA D 3 77  ? 89.359  118.478 96.775  1.00 124.56 ? 76  ALA c N   1 
ATOM 3148 C CA  . ALA D 3 77  ? 88.402  119.335 96.093  1.00 124.56 ? 76  ALA c CA  1 
ATOM 3149 C C   . ALA D 3 77  ? 87.043  118.651 95.993  1.00 124.56 ? 76  ALA c C   1 
ATOM 3150 O O   . ALA D 3 77  ? 86.940  117.422 95.968  1.00 124.56 ? 76  ALA c O   1 
ATOM 3151 C CB  . ALA D 3 77  ? 88.908  119.701 94.698  1.00 124.56 ? 76  ALA c CB  1 
ATOM 3152 N N   . ASN D 3 78  ? 85.993  119.466 95.939  1.00 131.78 ? 77  ASN c N   1 
ATOM 3153 C CA  . ASN D 3 78  ? 84.643  118.938 95.837  1.00 131.78 ? 77  ASN c CA  1 
ATOM 3154 C C   . ASN D 3 78  ? 84.422  118.285 94.475  1.00 131.78 ? 77  ASN c C   1 
ATOM 3155 O O   . ASN D 3 78  ? 85.123  118.562 93.498  1.00 131.78 ? 77  ASN c O   1 
ATOM 3156 C CB  . ASN D 3 78  ? 83.614  120.045 96.065  1.00 131.78 ? 77  ASN c CB  1 
ATOM 3157 C CG  . ASN D 3 78  ? 83.357  120.306 97.536  1.00 131.78 ? 77  ASN c CG  1 
ATOM 3158 O OD1 . ASN D 3 78  ? 83.233  119.374 98.331  1.00 131.78 ? 77  ASN c OD1 1 
ATOM 3159 N ND2 . ASN D 3 78  ? 83.278  121.579 97.907  1.00 131.78 ? 77  ASN c ND2 1 
ATOM 3160 N N   . GLY D 3 79  ? 83.427  117.403 94.422  1.00 129.51 ? 78  GLY c N   1 
ATOM 3161 C CA  . GLY D 3 79  ? 83.162  116.639 93.221  1.00 129.51 ? 78  GLY c CA  1 
ATOM 3162 C C   . GLY D 3 79  ? 84.011  115.401 93.055  1.00 129.51 ? 78  GLY c C   1 
ATOM 3163 O O   . GLY D 3 79  ? 83.945  114.762 91.999  1.00 129.51 ? 78  GLY c O   1 
ATOM 3164 N N   . SER D 3 80  ? 84.806  115.043 94.061  1.00 124.60 ? 79  SER c N   1 
ATOM 3165 C CA  . SER D 3 80  ? 85.661  113.868 93.993  1.00 124.60 ? 79  SER c CA  1 
ATOM 3166 C C   . SER D 3 80  ? 85.921  113.371 95.407  1.00 124.60 ? 79  SER c C   1 
ATOM 3167 O O   . SER D 3 80  ? 85.680  114.077 96.389  1.00 124.60 ? 79  SER c O   1 
ATOM 3168 C CB  . SER D 3 80  ? 86.981  114.169 93.275  1.00 124.60 ? 79  SER c CB  1 
ATOM 3169 O OG  . SER D 3 80  ? 86.773  114.369 91.888  1.00 124.60 ? 79  SER c OG  1 
ATOM 3170 N N   . CYS D 3 81  ? 86.417  112.139 95.499  1.00 114.90 ? 80  CYS c N   1 
ATOM 3171 C CA  . CYS D 3 81  ? 86.701  111.504 96.781  1.00 114.90 ? 80  CYS c CA  1 
ATOM 3172 C C   . CYS D 3 81  ? 88.184  111.297 97.038  1.00 114.90 ? 80  CYS c C   1 
ATOM 3173 O O   . CYS D 3 81  ? 88.646  111.520 98.159  1.00 114.90 ? 80  CYS c O   1 
ATOM 3174 C CB  . CYS D 3 81  ? 85.985  110.151 96.870  1.00 114.90 ? 80  CYS c CB  1 
ATOM 3175 S SG  . CYS D 3 81  ? 86.554  108.925 95.670  1.00 114.90 ? 80  CYS c SG  1 
ATOM 3176 N N   . ASP D 3 82  ? 88.941  110.876 96.035  1.00 106.17 ? 81  ASP c N   1 
ATOM 3177 C CA  . ASP D 3 82  ? 90.367  110.636 96.229  1.00 106.17 ? 81  ASP c CA  1 
ATOM 3178 C C   . ASP D 3 82  ? 91.145  111.951 96.261  1.00 106.17 ? 81  ASP c C   1 
ATOM 3179 O O   . ASP D 3 82  ? 90.956  112.803 95.389  1.00 106.17 ? 81  ASP c O   1 
ATOM 3180 C CB  . ASP D 3 82  ? 90.908  109.672 95.160  1.00 106.17 ? 81  ASP c CB  1 
ATOM 3181 C CG  . ASP D 3 82  ? 90.788  110.204 93.732  1.00 106.17 ? 81  ASP c CG  1 
ATOM 3182 O OD1 . ASP D 3 82  ? 90.248  111.303 93.505  1.00 106.17 ? 81  ASP c OD1 1 
ATOM 3183 O OD2 . ASP D 3 82  ? 91.249  109.494 92.814  1.00 106.17 ? 81  ASP c OD2 1 
ATOM 3184 N N   . PRO D 3 83  ? 91.973  112.175 97.278  1.00 97.67  ? 82  PRO c N   1 
ATOM 3185 C CA  . PRO D 3 83  ? 92.770  113.404 97.320  1.00 97.67  ? 82  PRO c CA  1 
ATOM 3186 C C   . PRO D 3 83  ? 93.824  113.425 96.226  1.00 97.67  ? 82  PRO c C   1 
ATOM 3187 O O   . PRO D 3 83  ? 94.304  112.385 95.768  1.00 97.67  ? 82  PRO c O   1 
ATOM 3188 C CB  . PRO D 3 83  ? 93.413  113.362 98.710  1.00 97.67  ? 82  PRO c CB  1 
ATOM 3189 C CG  . PRO D 3 83  ? 93.432  111.916 99.071  1.00 97.67  ? 82  PRO c CG  1 
ATOM 3190 C CD  . PRO D 3 83  ? 92.195  111.327 98.460  1.00 97.67  ? 82  PRO c CD  1 
ATOM 3191 N N   . SER D 3 84  ? 94.179  114.633 95.807  1.00 85.22  ? 83  SER c N   1 
ATOM 3192 C CA  . SER D 3 84  ? 95.209  114.862 94.804  1.00 85.22  ? 83  SER c CA  1 
ATOM 3193 C C   . SER D 3 84  ? 96.252  115.829 95.359  1.00 85.22  ? 83  SER c C   1 
ATOM 3194 O O   . SER D 3 84  ? 96.114  116.361 96.462  1.00 85.22  ? 83  SER c O   1 
ATOM 3195 C CB  . SER D 3 84  ? 94.597  115.397 93.507  1.00 85.22  ? 83  SER c CB  1 
ATOM 3196 O OG  . SER D 3 84  ? 93.965  116.647 93.721  1.00 85.22  ? 83  SER c OG  1 
ATOM 3197 N N   . VAL D 3 85  ? 97.305  116.055 94.578  1.00 73.71  ? 84  VAL c N   1 
ATOM 3198 C CA  . VAL D 3 85  ? 98.387  116.959 94.952  1.00 73.71  ? 84  VAL c CA  1 
ATOM 3199 C C   . VAL D 3 85  ? 98.180  118.290 94.245  1.00 73.71  ? 84  VAL c C   1 
ATOM 3200 O O   . VAL D 3 85  ? 97.917  118.329 93.036  1.00 73.71  ? 84  VAL c O   1 
ATOM 3201 C CB  . VAL D 3 85  ? 99.763  116.358 94.615  1.00 73.71  ? 84  VAL c CB  1 
ATOM 3202 C CG1 . VAL D 3 85  ? 100.106 115.251 95.592  1.00 73.71  ? 84  VAL c CG1 1 
ATOM 3203 C CG2 . VAL D 3 85  ? 99.782  115.828 93.190  1.00 73.71  ? 84  VAL c CG2 1 
ATOM 3204 N N   . THR D 3 86  ? 98.288  119.383 94.999  1.00 72.01  ? 85  THR c N   1 
ATOM 3205 C CA  . THR D 3 86  ? 98.115  120.726 94.456  1.00 72.01  ? 85  THR c CA  1 
ATOM 3206 C C   . THR D 3 86  ? 99.454  121.403 94.184  1.00 72.01  ? 85  THR c C   1 
ATOM 3207 O O   . THR D 3 86  ? 99.721  121.833 93.059  1.00 72.01  ? 85  THR c O   1 
ATOM 3208 C CB  . THR D 3 86  ? 97.272  121.577 95.414  1.00 72.01  ? 85  THR c CB  1 
ATOM 3209 O OG1 . THR D 3 86  ? 95.988  120.968 95.593  1.00 72.01  ? 85  THR c OG1 1 
ATOM 3210 C CG2 . THR D 3 86  ? 97.088  122.979 94.857  1.00 72.01  ? 85  THR c CG2 1 
ATOM 3211 N N   . ARG D 3 87  ? 100.306 121.501 95.201  1.00 66.13  ? 86  ARG c N   1 
ATOM 3212 C CA  . ARG D 3 87  ? 101.602 122.151 95.088  1.00 66.13  ? 86  ARG c CA  1 
ATOM 3213 C C   . ARG D 3 87  ? 102.650 121.313 95.805  1.00 66.13  ? 86  ARG c C   1 
ATOM 3214 O O   . ARG D 3 87  ? 102.334 120.460 96.638  1.00 66.13  ? 86  ARG c O   1 
ATOM 3215 C CB  . ARG D 3 87  ? 101.567 123.570 95.669  1.00 66.13  ? 86  ARG c CB  1 
ATOM 3216 C CG  . ARG D 3 87  ? 100.820 123.672 96.985  1.00 66.13  ? 86  ARG c CG  1 
ATOM 3217 C CD  . ARG D 3 87  ? 100.884 125.076 97.553  1.00 66.13  ? 86  ARG c CD  1 
ATOM 3218 N NE  . ARG D 3 87  ? 100.422 125.121 98.935  1.00 66.13  ? 86  ARG c NE  1 
ATOM 3219 C CZ  . ARG D 3 87  ? 99.147  125.134 99.298  1.00 66.13  ? 86  ARG c CZ  1 
ATOM 3220 N NH1 . ARG D 3 87  ? 98.173  125.120 98.403  1.00 66.13  ? 86  ARG c NH1 1 
ATOM 3221 N NH2 . ARG D 3 87  ? 98.841  125.164 100.592 1.00 66.13  ? 86  ARG c NH2 1 
ATOM 3222 N N   . GLN D 3 88  ? 103.913 121.566 95.473  1.00 52.79  ? 87  GLN c N   1 
ATOM 3223 C CA  . GLN D 3 88  ? 105.030 120.853 96.072  1.00 52.79  ? 87  GLN c CA  1 
ATOM 3224 C C   . GLN D 3 88  ? 106.146 121.833 96.394  1.00 52.79  ? 87  GLN c C   1 
ATOM 3225 O O   . GLN D 3 88  ? 106.336 122.824 95.684  1.00 52.79  ? 87  GLN c O   1 
ATOM 3226 C CB  . GLN D 3 88  ? 105.549 119.753 95.139  1.00 52.79  ? 87  GLN c CB  1 
ATOM 3227 C CG  . GLN D 3 88  ? 104.727 118.479 95.173  1.00 52.79  ? 87  GLN c CG  1 
ATOM 3228 C CD  . GLN D 3 88  ? 105.409 117.327 94.466  1.00 52.79  ? 87  GLN c CD  1 
ATOM 3229 O OE1 . GLN D 3 88  ? 106.575 117.420 94.086  1.00 52.79  ? 87  GLN c OE1 1 
ATOM 3230 N NE2 . GLN D 3 88  ? 104.683 116.230 94.287  1.00 52.79  ? 87  GLN c NE2 1 
ATOM 3231 N N   . ALA D 3 89  ? 106.879 121.552 97.467  1.00 41.75  ? 88  ALA c N   1 
ATOM 3232 C CA  . ALA D 3 89  ? 108.033 122.344 97.873  1.00 41.75  ? 88  ALA c CA  1 
ATOM 3233 C C   . ALA D 3 89  ? 109.283 121.494 97.701  1.00 41.75  ? 88  ALA c C   1 
ATOM 3234 O O   . ALA D 3 89  ? 109.365 120.391 98.250  1.00 41.75  ? 88  ALA c O   1 
ATOM 3235 C CB  . ALA D 3 89  ? 107.895 122.820 99.318  1.00 41.75  ? 88  ALA c CB  1 
ATOM 3236 N N   . TYR D 3 90  ? 110.250 122.005 96.949  1.00 37.56  ? 89  TYR c N   1 
ATOM 3237 C CA  . TYR D 3 90  ? 111.447 121.259 96.596  1.00 37.56  ? 89  TYR c CA  1 
ATOM 3238 C C   . TYR D 3 90  ? 112.645 121.747 97.400  1.00 37.56  ? 89  TYR c C   1 
ATOM 3239 O O   . TYR D 3 90  ? 112.590 122.755 98.108  1.00 37.56  ? 89  TYR c O   1 
ATOM 3240 C CB  . TYR D 3 90  ? 111.738 121.378 95.096  1.00 37.56  ? 89  TYR c CB  1 
ATOM 3241 C CG  . TYR D 3 90  ? 110.713 120.708 94.213  1.00 37.56  ? 89  TYR c CG  1 
ATOM 3242 C CD1 . TYR D 3 90  ? 110.342 119.389 94.426  1.00 37.56  ? 89  TYR c CD1 1 
ATOM 3243 C CD2 . TYR D 3 90  ? 110.118 121.395 93.165  1.00 37.56  ? 89  TYR c CD2 1 
ATOM 3244 C CE1 . TYR D 3 90  ? 109.406 118.773 93.621  1.00 37.56  ? 89  TYR c CE1 1 
ATOM 3245 C CE2 . TYR D 3 90  ? 109.180 120.787 92.354  1.00 37.56  ? 89  TYR c CE2 1 
ATOM 3246 C CZ  . TYR D 3 90  ? 108.828 119.476 92.586  1.00 37.56  ? 89  TYR c CZ  1 
ATOM 3247 O OH  . TYR D 3 90  ? 107.895 118.865 91.782  1.00 37.56  ? 89  TYR c OH  1 
ATOM 3248 N N   . ALA D 3 91  ? 113.739 121.001 97.276  1.00 34.35  ? 90  ALA c N   1 
ATOM 3249 C CA  . ALA D 3 91  ? 115.015 121.360 97.876  1.00 34.35  ? 90  ALA c CA  1 
ATOM 3250 C C   . ALA D 3 91  ? 116.107 120.609 97.132  1.00 34.35  ? 90  ALA c C   1 
ATOM 3251 O O   . ALA D 3 91  ? 115.841 119.629 96.433  1.00 34.35  ? 90  ALA c O   1 
ATOM 3252 C CB  . ALA D 3 91  ? 115.053 121.040 99.373  1.00 34.35  ? 90  ALA c CB  1 
ATOM 3253 N N   . ASP D 3 92  ? 117.340 121.079 97.289  1.00 34.12  ? 91  ASP c N   1 
ATOM 3254 C CA  . ASP D 3 92  ? 118.459 120.485 96.574  1.00 34.12  ? 91  ASP c CA  1 
ATOM 3255 C C   . ASP D 3 92  ? 119.757 120.897 97.248  1.00 34.12  ? 91  ASP c C   1 
ATOM 3256 O O   . ASP D 3 92  ? 119.935 122.064 97.600  1.00 34.12  ? 91  ASP c O   1 
ATOM 3257 C CB  . ASP D 3 92  ? 118.465 120.914 95.103  1.00 34.12  ? 91  ASP c CB  1 
ATOM 3258 C CG  . ASP D 3 92  ? 119.303 120.003 94.234  1.00 34.12  ? 91  ASP c CG  1 
ATOM 3259 O OD1 . ASP D 3 92  ? 120.516 119.875 94.499  1.00 34.12  ? 91  ASP c OD1 1 
ATOM 3260 O OD2 . ASP D 3 92  ? 118.749 119.417 93.281  1.00 34.12  ? 91  ASP c OD2 1 
ATOM 3261 N N   . VAL D 3 93  ? 120.654 119.931 97.427  1.00 36.63  ? 92  VAL c N   1 
ATOM 3262 C CA  . VAL D 3 93  ? 121.970 120.168 98.009  1.00 36.63  ? 92  VAL c CA  1 
ATOM 3263 C C   . VAL D 3 93  ? 122.986 119.345 97.230  1.00 36.63  ? 92  VAL c C   1 
ATOM 3264 O O   . VAL D 3 93  ? 122.743 118.174 96.925  1.00 36.63  ? 92  VAL c O   1 
ATOM 3265 C CB  . VAL D 3 93  ? 122.003 119.806 99.509  1.00 36.63  ? 92  VAL c CB  1 
ATOM 3266 C CG1 . VAL D 3 93  ? 123.423 119.829 100.032 1.00 36.63  ? 92  VAL c CG1 1 
ATOM 3267 C CG2 . VAL D 3 93  ? 121.132 120.757 100.311 1.00 36.63  ? 92  VAL c CG2 1 
ATOM 3268 N N   . THR D 3 94  ? 124.123 119.955 96.905  1.00 35.40  ? 93  THR c N   1 
ATOM 3269 C CA  . THR D 3 94  ? 125.171 119.253 96.179  1.00 35.40  ? 93  THR c CA  1 
ATOM 3270 C C   . THR D 3 94  ? 126.537 119.712 96.668  1.00 35.40  ? 93  THR c C   1 
ATOM 3271 O O   . THR D 3 94  ? 126.727 120.888 96.990  1.00 35.40  ? 93  THR c O   1 
ATOM 3272 C CB  . THR D 3 94  ? 125.046 119.463 94.664  1.00 35.40  ? 93  THR c CB  1 
ATOM 3273 O OG1 . THR D 3 94  ? 126.132 118.810 93.996  1.00 35.40  ? 93  THR c OG1 1 
ATOM 3274 C CG2 . THR D 3 94  ? 125.055 120.938 94.317  1.00 35.40  ? 93  THR c CG2 1 
ATOM 3275 N N   . PHE D 3 95  ? 127.476 118.772 96.736  1.00 41.35  ? 94  PHE c N   1 
ATOM 3276 C CA  . PHE D 3 95  ? 128.848 119.040 97.137  1.00 41.35  ? 94  PHE c CA  1 
ATOM 3277 C C   . PHE D 3 95  ? 129.793 118.594 96.031  1.00 41.35  ? 94  PHE c C   1 
ATOM 3278 O O   . PHE D 3 95  ? 129.480 117.683 95.260  1.00 41.35  ? 94  PHE c O   1 
ATOM 3279 C CB  . PHE D 3 95  ? 129.200 118.320 98.442  1.00 41.35  ? 94  PHE c CB  1 
ATOM 3280 C CG  . PHE D 3 95  ? 128.331 118.707 99.604  1.00 41.35  ? 94  PHE c CG  1 
ATOM 3281 C CD1 . PHE D 3 95  ? 128.648 119.799 100.391 1.00 41.35  ? 94  PHE c CD1 1 
ATOM 3282 C CD2 . PHE D 3 95  ? 127.204 117.971 99.917  1.00 41.35  ? 94  PHE c CD2 1 
ATOM 3283 C CE1 . PHE D 3 95  ? 127.853 120.153 101.462 1.00 41.35  ? 94  PHE c CE1 1 
ATOM 3284 C CE2 . PHE D 3 95  ? 126.407 118.319 100.987 1.00 41.35  ? 94  PHE c CE2 1 
ATOM 3285 C CZ  . PHE D 3 95  ? 126.731 119.412 101.760 1.00 41.35  ? 94  PHE c CZ  1 
ATOM 3286 N N   . SER D 3 96  ? 130.950 119.245 95.949  1.00 44.33  ? 95  SER c N   1 
ATOM 3287 C CA  . SER D 3 96  ? 131.902 119.012 94.866  1.00 44.33  ? 95  SER c CA  1 
ATOM 3288 C C   . SER D 3 96  ? 133.327 118.913 95.400  1.00 44.33  ? 95  SER c C   1 
ATOM 3289 O O   . SER D 3 96  ? 134.241 119.590 94.926  1.00 44.33  ? 95  SER c O   1 
ATOM 3290 C CB  . SER D 3 96  ? 131.800 120.106 93.809  1.00 44.33  ? 95  SER c CB  1 
ATOM 3291 O OG  . SER D 3 96  ? 132.714 119.876 92.753  1.00 44.33  ? 95  SER c OG  1 
ATOM 3292 N N   . PHE D 3 97  ? 133.536 118.067 96.406  1.00 48.30  ? 96  PHE c N   1 
ATOM 3293 C CA  . PHE D 3 97  ? 134.878 117.840 96.920  1.00 48.30  ? 96  PHE c CA  1 
ATOM 3294 C C   . PHE D 3 97  ? 135.764 117.200 95.850  1.00 48.30  ? 96  PHE c C   1 
ATOM 3295 O O   . PHE D 3 97  ? 135.296 116.723 94.815  1.00 48.30  ? 96  PHE c O   1 
ATOM 3296 C CB  . PHE D 3 97  ? 134.835 116.955 98.163  1.00 48.30  ? 96  PHE c CB  1 
ATOM 3297 C CG  . PHE D 3 97  ? 133.797 117.365 99.161  1.00 48.30  ? 96  PHE c CG  1 
ATOM 3298 C CD1 . PHE D 3 97  ? 133.825 118.627 99.727  1.00 48.30  ? 96  PHE c CD1 1 
ATOM 3299 C CD2 . PHE D 3 97  ? 132.795 116.490 99.536  1.00 48.30  ? 96  PHE c CD2 1 
ATOM 3300 C CE1 . PHE D 3 97  ? 132.872 119.009 100.646 1.00 48.30  ? 96  PHE c CE1 1 
ATOM 3301 C CE2 . PHE D 3 97  ? 131.839 116.866 100.456 1.00 48.30  ? 96  PHE c CE2 1 
ATOM 3302 C CZ  . PHE D 3 97  ? 131.878 118.128 101.011 1.00 48.30  ? 96  PHE c CZ  1 
ATOM 3303 N N   . THR D 3 98  ? 137.066 117.191 96.116  1.00 56.98  ? 97  THR c N   1 
ATOM 3304 C CA  . THR D 3 98  ? 138.063 116.671 95.188  1.00 56.98  ? 97  THR c CA  1 
ATOM 3305 C C   . THR D 3 98  ? 138.794 115.484 95.812  1.00 56.98  ? 97  THR c C   1 
ATOM 3306 O O   . THR D 3 98  ? 138.520 115.079 96.944  1.00 56.98  ? 97  THR c O   1 
ATOM 3307 C CB  . THR D 3 98  ? 139.052 117.765 94.780  1.00 56.98  ? 97  THR c CB  1 
ATOM 3308 O OG1 . THR D 3 98  ? 140.089 117.195 93.973  1.00 56.98  ? 97  THR c OG1 1 
ATOM 3309 C CG2 . THR D 3 98  ? 139.669 118.408 96.009  1.00 56.98  ? 97  THR c CG2 1 
ATOM 3310 N N   . GLN D 3 99  ? 139.742 114.928 95.052  1.00 61.53  ? 98  GLN c N   1 
ATOM 3311 C CA  . GLN D 3 99  ? 140.424 113.710 95.482  1.00 61.53  ? 98  GLN c CA  1 
ATOM 3312 C C   . GLN D 3 99  ? 141.370 113.970 96.647  1.00 61.53  ? 98  GLN c C   1 
ATOM 3313 O O   . GLN D 3 99  ? 141.478 113.142 97.559  1.00 61.53  ? 98  GLN c O   1 
ATOM 3314 C CB  . GLN D 3 99  ? 141.189 113.093 94.313  1.00 61.53  ? 98  GLN c CB  1 
ATOM 3315 C CG  . GLN D 3 99  ? 140.316 112.356 93.318  1.00 61.53  ? 98  GLN c CG  1 
ATOM 3316 C CD  . GLN D 3 99  ? 141.126 111.663 92.242  1.00 61.53  ? 98  GLN c CD  1 
ATOM 3317 O OE1 . GLN D 3 99  ? 142.341 111.837 92.155  1.00 61.53  ? 98  GLN c OE1 1 
ATOM 3318 N NE2 . GLN D 3 99  ? 140.455 110.866 91.419  1.00 61.53  ? 98  GLN c NE2 1 
ATOM 3319 N N   . TYR D 3 100 ? 142.068 115.106 96.637  1.00 62.23  ? 99  TYR c N   1 
ATOM 3320 C CA  . TYR D 3 100 ? 143.085 115.401 97.640  1.00 62.23  ? 99  TYR c CA  1 
ATOM 3321 C C   . TYR D 3 100 ? 142.541 116.201 98.815  1.00 62.23  ? 99  TYR c C   1 
ATOM 3322 O O   . TYR D 3 100 ? 143.280 116.992 99.415  1.00 62.23  ? 99  TYR c O   1 
ATOM 3323 C CB  . TYR D 3 100 ? 144.257 116.142 96.996  1.00 62.23  ? 99  TYR c CB  1 
ATOM 3324 C CG  . TYR D 3 100 ? 145.066 115.302 96.034  1.00 62.23  ? 99  TYR c CG  1 
ATOM 3325 C CD1 . TYR D 3 100 ? 146.112 114.510 96.485  1.00 62.23  ? 99  TYR c CD1 1 
ATOM 3326 C CD2 . TYR D 3 100 ? 144.788 115.307 94.675  1.00 62.23  ? 99  TYR c CD2 1 
ATOM 3327 C CE1 . TYR D 3 100 ? 146.856 113.744 95.610  1.00 62.23  ? 99  TYR c CE1 1 
ATOM 3328 C CE2 . TYR D 3 100 ? 145.525 114.544 93.793  1.00 62.23  ? 99  TYR c CE2 1 
ATOM 3329 C CZ  . TYR D 3 100 ? 146.558 113.765 94.266  1.00 62.23  ? 99  TYR c CZ  1 
ATOM 3330 O OH  . TYR D 3 100 ? 147.295 113.003 93.390  1.00 62.23  ? 99  TYR c OH  1 
ATOM 3331 N N   . SER D 3 101 ? 141.272 116.018 99.166  1.00 59.35  ? 100 SER c N   1 
ATOM 3332 C CA  . SER D 3 101 ? 140.643 116.763 100.248 1.00 59.35  ? 100 SER c CA  1 
ATOM 3333 C C   . SER D 3 101 ? 140.546 115.876 101.482 1.00 59.35  ? 100 SER c C   1 
ATOM 3334 O O   . SER D 3 101 ? 139.927 114.808 101.436 1.00 59.35  ? 100 SER c O   1 
ATOM 3335 C CB  . SER D 3 101 ? 139.259 117.257 99.832  1.00 59.35  ? 100 SER c CB  1 
ATOM 3336 O OG  . SER D 3 101 ? 138.524 116.224 99.202  1.00 59.35  ? 100 SER c OG  1 
ATOM 3337 N N   . THR D 3 102 ? 141.152 116.322 102.578 1.00 61.57  ? 101 THR c N   1 
ATOM 3338 C CA  . THR D 3 102 ? 141.070 115.592 103.832 1.00 61.57  ? 101 THR c CA  1 
ATOM 3339 C C   . THR D 3 102 ? 139.682 115.748 104.449 1.00 61.57  ? 101 THR c C   1 
ATOM 3340 O O   . THR D 3 102 ? 138.900 116.624 104.073 1.00 61.57  ? 101 THR c O   1 
ATOM 3341 C CB  . THR D 3 102 ? 142.135 116.081 104.812 1.00 61.57  ? 101 THR c CB  1 
ATOM 3342 O OG1 . THR D 3 102 ? 141.728 117.335 105.372 1.00 61.57  ? 101 THR c OG1 1 
ATOM 3343 C CG2 . THR D 3 102 ? 143.465 116.261 104.100 1.00 61.57  ? 101 THR c CG2 1 
ATOM 3344 N N   . ASP D 3 103 ? 139.381 114.875 105.413 1.00 60.77  ? 102 ASP c N   1 
ATOM 3345 C CA  . ASP D 3 103 ? 138.067 114.892 106.047 1.00 60.77  ? 102 ASP c CA  1 
ATOM 3346 C C   . ASP D 3 103 ? 137.828 116.150 106.870 1.00 60.77  ? 102 ASP c C   1 
ATOM 3347 O O   . ASP D 3 103 ? 136.669 116.497 107.122 1.00 60.77  ? 102 ASP c O   1 
ATOM 3348 C CB  . ASP D 3 103 ? 137.890 113.656 106.929 1.00 60.77  ? 102 ASP c CB  1 
ATOM 3349 C CG  . ASP D 3 103 ? 139.012 113.491 107.933 1.00 60.77  ? 102 ASP c CG  1 
ATOM 3350 O OD1 . ASP D 3 103 ? 139.996 114.257 107.859 1.00 60.77  ? 102 ASP c OD1 1 
ATOM 3351 O OD2 . ASP D 3 103 ? 138.911 112.595 108.797 1.00 60.77  ? 102 ASP c OD2 1 
ATOM 3352 N N   . GLU D 3 104 ? 138.890 116.839 107.294 1.00 60.04  ? 103 GLU c N   1 
ATOM 3353 C CA  . GLU D 3 104 ? 138.719 118.055 108.082 1.00 60.04  ? 103 GLU c CA  1 
ATOM 3354 C C   . GLU D 3 104 ? 137.983 119.126 107.286 1.00 60.04  ? 103 GLU c C   1 
ATOM 3355 O O   . GLU D 3 104 ? 137.045 119.756 107.789 1.00 60.04  ? 103 GLU c O   1 
ATOM 3356 C CB  . GLU D 3 104 ? 140.080 118.573 108.547 1.00 60.04  ? 103 GLU c CB  1 
ATOM 3357 C CG  . GLU D 3 104 ? 140.922 117.543 109.276 1.00 60.04  ? 103 GLU c CG  1 
ATOM 3358 C CD  . GLU D 3 104 ? 140.384 117.221 110.654 1.00 60.04  ? 103 GLU c CD  1 
ATOM 3359 O OE1 . GLU D 3 104 ? 139.811 118.127 111.295 1.00 60.04  ? 103 GLU c OE1 1 
ATOM 3360 O OE2 . GLU D 3 104 ? 140.534 116.063 111.097 1.00 60.04  ? 103 GLU c OE2 1 
ATOM 3361 N N   . GLU D 3 105 ? 138.391 119.339 106.033 1.00 59.47  ? 104 GLU c N   1 
ATOM 3362 C CA  . GLU D 3 105 ? 137.753 120.359 105.206 1.00 59.47  ? 104 GLU c CA  1 
ATOM 3363 C C   . GLU D 3 105 ? 136.302 120.006 104.906 1.00 59.47  ? 104 GLU c C   1 
ATOM 3364 O O   . GLU D 3 105 ? 135.423 120.876 104.934 1.00 59.47  ? 104 GLU c O   1 
ATOM 3365 C CB  . GLU D 3 105 ? 138.544 120.545 103.913 1.00 59.47  ? 104 GLU c CB  1 
ATOM 3366 C CG  . GLU D 3 105 ? 138.017 121.641 103.008 1.00 59.47  ? 104 GLU c CG  1 
ATOM 3367 C CD  . GLU D 3 105 ? 138.865 121.821 101.764 1.00 59.47  ? 104 GLU c CD  1 
ATOM 3368 O OE1 . GLU D 3 105 ? 139.851 121.071 101.604 1.00 59.47  ? 104 GLU c OE1 1 
ATOM 3369 O OE2 . GLU D 3 105 ? 138.548 122.712 100.949 1.00 59.47  ? 104 GLU c OE2 1 
ATOM 3370 N N   . ARG D 3 106 ? 136.030 118.732 104.615 1.00 52.23  ? 105 ARG c N   1 
ATOM 3371 C CA  . ARG D 3 106 ? 134.661 118.315 104.331 1.00 52.23  ? 105 ARG c CA  1 
ATOM 3372 C C   . ARG D 3 106 ? 133.769 118.481 105.555 1.00 52.23  ? 105 ARG c C   1 
ATOM 3373 O O   . ARG D 3 106 ? 132.629 118.954 105.446 1.00 52.23  ? 105 ARG c O   1 
ATOM 3374 C CB  . ARG D 3 106 ? 134.652 116.868 103.841 1.00 52.23  ? 105 ARG c CB  1 
ATOM 3375 C CG  . ARG D 3 106 ? 135.413 116.664 102.542 1.00 52.23  ? 105 ARG c CG  1 
ATOM 3376 C CD  . ARG D 3 106 ? 135.326 115.229 102.054 1.00 52.23  ? 105 ARG c CD  1 
ATOM 3377 N NE  . ARG D 3 106 ? 135.947 114.295 102.984 1.00 52.23  ? 105 ARG c NE  1 
ATOM 3378 C CZ  . ARG D 3 106 ? 136.913 113.447 102.659 1.00 52.23  ? 105 ARG c CZ  1 
ATOM 3379 N NH1 . ARG D 3 106 ? 137.406 113.399 101.433 1.00 52.23  ? 105 ARG c NH1 1 
ATOM 3380 N NH2 . ARG D 3 106 ? 137.399 112.630 103.588 1.00 52.23  ? 105 ARG c NH2 1 
ATOM 3381 N N   . ALA D 3 107 ? 134.272 118.104 106.732 1.00 51.28  ? 106 ALA c N   1 
ATOM 3382 C CA  . ALA D 3 107 ? 133.502 118.292 107.956 1.00 51.28  ? 106 ALA c CA  1 
ATOM 3383 C C   . ALA D 3 107 ? 133.267 119.770 108.233 1.00 51.28  ? 106 ALA c C   1 
ATOM 3384 O O   . ALA D 3 107 ? 132.179 120.161 108.672 1.00 51.28  ? 106 ALA c O   1 
ATOM 3385 C CB  . ALA D 3 107 ? 134.215 117.629 109.134 1.00 51.28  ? 106 ALA c CB  1 
ATOM 3386 N N   . PHE D 3 108 ? 134.277 120.608 107.983 1.00 50.02  ? 107 PHE c N   1 
ATOM 3387 C CA  . PHE D 3 108 ? 134.105 122.044 108.167 1.00 50.02  ? 107 PHE c CA  1 
ATOM 3388 C C   . PHE D 3 108 ? 133.017 122.588 107.252 1.00 50.02  ? 107 PHE c C   1 
ATOM 3389 O O   . PHE D 3 108 ? 132.174 123.381 107.684 1.00 50.02  ? 107 PHE c O   1 
ATOM 3390 C CB  . PHE D 3 108 ? 135.428 122.767 107.916 1.00 50.02  ? 107 PHE c CB  1 
ATOM 3391 C CG  . PHE D 3 108 ? 135.423 124.209 108.337 1.00 50.02  ? 107 PHE c CG  1 
ATOM 3392 C CD1 . PHE D 3 108 ? 134.908 125.188 107.506 1.00 50.02  ? 107 PHE c CD1 1 
ATOM 3393 C CD2 . PHE D 3 108 ? 135.937 124.585 109.566 1.00 50.02  ? 107 PHE c CD2 1 
ATOM 3394 C CE1 . PHE D 3 108 ? 134.903 126.512 107.893 1.00 50.02  ? 107 PHE c CE1 1 
ATOM 3395 C CE2 . PHE D 3 108 ? 135.935 125.908 109.957 1.00 50.02  ? 107 PHE c CE2 1 
ATOM 3396 C CZ  . PHE D 3 108 ? 135.417 126.872 109.120 1.00 50.02  ? 107 PHE c CZ  1 
ATOM 3397 N N   . VAL D 3 109 ? 133.018 122.170 105.984 1.00 47.34  ? 108 VAL c N   1 
ATOM 3398 C CA  . VAL D 3 109 ? 132.001 122.644 105.047 1.00 47.34  ? 108 VAL c CA  1 
ATOM 3399 C C   . VAL D 3 109 ? 130.615 122.193 105.489 1.00 47.34  ? 108 VAL c C   1 
ATOM 3400 O O   . VAL D 3 109 ? 129.655 122.976 105.470 1.00 47.34  ? 108 VAL c O   1 
ATOM 3401 C CB  . VAL D 3 109 ? 132.323 122.167 103.620 1.00 47.34  ? 108 VAL c CB  1 
ATOM 3402 C CG1 . VAL D 3 109 ? 131.135 122.398 102.705 1.00 47.34  ? 108 VAL c CG1 1 
ATOM 3403 C CG2 . VAL D 3 109 ? 133.550 122.884 103.089 1.00 47.34  ? 108 VAL c CG2 1 
ATOM 3404 N N   . ARG D 3 110 ? 130.486 120.926 105.894 1.00 46.62  ? 109 ARG c N   1 
ATOM 3405 C CA  . ARG D 3 110 ? 129.182 120.419 106.310 1.00 46.62  ? 109 ARG c CA  1 
ATOM 3406 C C   . ARG D 3 110 ? 128.666 121.164 107.535 1.00 46.62  ? 109 ARG c C   1 
ATOM 3407 O O   . ARG D 3 110 ? 127.493 121.551 107.591 1.00 46.62  ? 109 ARG c O   1 
ATOM 3408 C CB  . ARG D 3 110 ? 129.258 118.920 106.589 1.00 46.62  ? 109 ARG c CB  1 
ATOM 3409 C CG  . ARG D 3 110 ? 127.993 118.360 107.219 1.00 46.62  ? 109 ARG c CG  1 
ATOM 3410 C CD  . ARG D 3 110 ? 128.184 116.933 107.690 1.00 46.62  ? 109 ARG c CD  1 
ATOM 3411 N NE  . ARG D 3 110 ? 129.246 116.823 108.682 1.00 46.62  ? 109 ARG c NE  1 
ATOM 3412 C CZ  . ARG D 3 110 ? 129.066 116.960 109.988 1.00 46.62  ? 109 ARG c CZ  1 
ATOM 3413 N NH1 . ARG D 3 110 ? 127.875 117.226 110.497 1.00 46.62  ? 109 ARG c NH1 1 
ATOM 3414 N NH2 . ARG D 3 110 ? 130.108 116.829 110.804 1.00 46.62  ? 109 ARG c NH2 1 
ATOM 3415 N N   . THR D 3 111 ? 129.532 121.380 108.530 1.00 49.11  ? 110 THR c N   1 
ATOM 3416 C CA  . THR D 3 111 ? 129.105 122.087 109.734 1.00 49.11  ? 110 THR c CA  1 
ATOM 3417 C C   . THR D 3 111 ? 128.768 123.542 109.436 1.00 49.11  ? 110 THR c C   1 
ATOM 3418 O O   . THR D 3 111 ? 127.813 124.089 110.001 1.00 49.11  ? 110 THR c O   1 
ATOM 3419 C CB  . THR D 3 111 ? 130.181 121.998 110.813 1.00 49.11  ? 110 THR c CB  1 
ATOM 3420 O OG1 . THR D 3 111 ? 131.431 122.458 110.285 1.00 49.11  ? 110 THR c OG1 1 
ATOM 3421 C CG2 . THR D 3 111 ? 130.330 120.566 111.301 1.00 49.11  ? 110 THR c CG2 1 
ATOM 3422 N N   . GLU D 3 112 ? 129.537 124.188 108.556 1.00 48.81  ? 111 GLU c N   1 
ATOM 3423 C CA  . GLU D 3 112 ? 129.233 125.563 108.174 1.00 48.81  ? 111 GLU c CA  1 
ATOM 3424 C C   . GLU D 3 112 ? 127.865 125.655 107.516 1.00 48.81  ? 111 GLU c C   1 
ATOM 3425 O O   . GLU D 3 112 ? 127.064 126.541 107.840 1.00 48.81  ? 111 GLU c O   1 
ATOM 3426 C CB  . GLU D 3 112 ? 130.316 126.094 107.236 1.00 48.81  ? 111 GLU c CB  1 
ATOM 3427 C CG  . GLU D 3 112 ? 130.138 127.546 106.836 1.00 48.81  ? 111 GLU c CG  1 
ATOM 3428 C CD  . GLU D 3 112 ? 131.259 128.045 105.946 1.00 48.81  ? 111 GLU c CD  1 
ATOM 3429 O OE1 . GLU D 3 112 ? 132.165 127.248 105.626 1.00 48.81  ? 111 GLU c OE1 1 
ATOM 3430 O OE2 . GLU D 3 112 ? 131.233 129.232 105.561 1.00 48.81  ? 111 GLU c OE2 1 
ATOM 3431 N N   . LEU D 3 113 ? 127.573 124.738 106.592 1.00 44.83  ? 112 LEU c N   1 
ATOM 3432 C CA  . LEU D 3 113 ? 126.273 124.760 105.930 1.00 44.83  ? 112 LEU c CA  1 
ATOM 3433 C C   . LEU D 3 113 ? 125.148 124.462 106.914 1.00 44.83  ? 112 LEU c C   1 
ATOM 3434 O O   . LEU D 3 113 ? 124.074 125.070 106.841 1.00 44.83  ? 112 LEU c O   1 
ATOM 3435 C CB  . LEU D 3 113 ? 126.252 123.766 104.772 1.00 44.83  ? 112 LEU c CB  1 
ATOM 3436 C CG  . LEU D 3 113 ? 124.955 123.753 103.965 1.00 44.83  ? 112 LEU c CG  1 
ATOM 3437 C CD1 . LEU D 3 113 ? 124.733 125.104 103.308 1.00 44.83  ? 112 LEU c CD1 1 
ATOM 3438 C CD2 . LEU D 3 113 ? 124.980 122.649 102.924 1.00 44.83  ? 112 LEU c CD2 1 
ATOM 3439 N N   . ALA D 3 114 ? 125.373 123.528 107.841 1.00 44.54  ? 113 ALA c N   1 
ATOM 3440 C CA  . ALA D 3 114 ? 124.335 123.180 108.806 1.00 44.54  ? 113 ALA c CA  1 
ATOM 3441 C C   . ALA D 3 114 ? 124.039 124.336 109.753 1.00 44.54  ? 113 ALA c C   1 
ATOM 3442 O O   . ALA D 3 114 ? 122.875 124.597 110.075 1.00 44.54  ? 113 ALA c O   1 
ATOM 3443 C CB  . ALA D 3 114 ? 124.744 121.936 109.593 1.00 44.54  ? 113 ALA c CB  1 
ATOM 3444 N N   . ALA D 3 115 ? 125.074 125.038 110.214 1.00 43.14  ? 114 ALA c N   1 
ATOM 3445 C CA  . ALA D 3 115 ? 124.874 126.140 111.146 1.00 43.14  ? 114 ALA c CA  1 
ATOM 3446 C C   . ALA D 3 115 ? 124.484 127.440 110.459 1.00 43.14  ? 114 ALA c C   1 
ATOM 3447 O O   . ALA D 3 115 ? 124.027 128.364 111.138 1.00 43.14  ? 114 ALA c O   1 
ATOM 3448 C CB  . ALA D 3 115 ? 126.136 126.364 111.980 1.00 43.14  ? 114 ALA c CB  1 
ATOM 3449 N N   . LEU D 3 116 ? 124.652 127.538 109.141 1.00 43.32  ? 115 LEU c N   1 
ATOM 3450 C CA  . LEU D 3 116 ? 124.232 128.731 108.419 1.00 43.32  ? 115 LEU c CA  1 
ATOM 3451 C C   . LEU D 3 116 ? 122.736 128.751 108.135 1.00 43.32  ? 115 LEU c C   1 
ATOM 3452 O O   . LEU D 3 116 ? 122.208 129.803 107.762 1.00 43.32  ? 115 LEU c O   1 
ATOM 3453 C CB  . LEU D 3 116 ? 125.011 128.844 107.107 1.00 43.32  ? 115 LEU c CB  1 
ATOM 3454 C CG  . LEU D 3 116 ? 125.085 130.222 106.452 1.00 43.32  ? 115 LEU c CG  1 
ATOM 3455 C CD1 . LEU D 3 116 ? 125.601 131.249 107.440 1.00 43.32  ? 115 LEU c CD1 1 
ATOM 3456 C CD2 . LEU D 3 116 ? 125.970 130.169 105.221 1.00 43.32  ? 115 LEU c CD2 1 
ATOM 3457 N N   . LEU D 3 117 ? 122.046 127.628 108.310 1.00 42.10  ? 116 LEU c N   1 
ATOM 3458 C CA  . LEU D 3 117 ? 120.613 127.542 108.066 1.00 42.10  ? 116 LEU c CA  1 
ATOM 3459 C C   . LEU D 3 117 ? 119.781 127.899 109.290 1.00 42.10  ? 116 LEU c C   1 
ATOM 3460 O O   . LEU D 3 117 ? 118.549 127.856 109.217 1.00 42.10  ? 116 LEU c O   1 
ATOM 3461 C CB  . LEU D 3 117 ? 120.243 126.135 107.589 1.00 42.10  ? 116 LEU c CB  1 
ATOM 3462 C CG  . LEU D 3 117 ? 120.532 125.814 106.123 1.00 42.10  ? 116 LEU c CG  1 
ATOM 3463 C CD1 . LEU D 3 117 ? 119.985 124.447 105.763 1.00 42.10  ? 116 LEU c CD1 1 
ATOM 3464 C CD2 . LEU D 3 117 ? 119.944 126.880 105.219 1.00 42.10  ? 116 LEU c CD2 1 
ATOM 3465 N N   . ALA D 3 118 ? 120.418 128.242 110.408 1.00 44.96  ? 117 ALA c N   1 
ATOM 3466 C CA  . ALA D 3 118 ? 119.713 128.664 111.607 1.00 44.96  ? 117 ALA c CA  1 
ATOM 3467 C C   . ALA D 3 118 ? 119.976 130.112 111.988 1.00 44.96  ? 117 ALA c C   1 
ATOM 3468 O O   . ALA D 3 118 ? 119.335 130.612 112.919 1.00 44.96  ? 117 ALA c O   1 
ATOM 3469 C CB  . ALA D 3 118 ? 120.081 127.760 112.794 1.00 44.96  ? 117 ALA c CB  1 
ATOM 3470 N N   . SER D 3 119 ? 120.894 130.794 111.308 1.00 49.12  ? 118 SER c N   1 
ATOM 3471 C CA  . SER D 3 119 ? 121.157 132.193 111.583 1.00 49.12  ? 118 SER c CA  1 
ATOM 3472 C C   . SER D 3 119 ? 119.961 133.042 111.161 1.00 49.12  ? 118 SER c C   1 
ATOM 3473 O O   . SER D 3 119 ? 119.178 132.638 110.298 1.00 49.12  ? 118 SER c O   1 
ATOM 3474 C CB  . SER D 3 119 ? 122.416 132.646 110.850 1.00 49.12  ? 118 SER c CB  1 
ATOM 3475 O OG  . SER D 3 119 ? 122.198 132.697 109.452 1.00 49.12  ? 118 SER c OG  1 
ATOM 3476 N N   . PRO D 3 120 ? 119.794 134.226 111.759 1.00 55.27  ? 119 PRO c N   1 
ATOM 3477 C CA  . PRO D 3 120 ? 118.626 135.055 111.418 1.00 55.27  ? 119 PRO c CA  1 
ATOM 3478 C C   . PRO D 3 120 ? 118.541 135.416 109.946 1.00 55.27  ? 119 PRO c C   1 
ATOM 3479 O O   . PRO D 3 120 ? 117.431 135.572 109.421 1.00 55.27  ? 119 PRO c O   1 
ATOM 3480 C CB  . PRO D 3 120 ? 118.811 136.302 112.296 1.00 55.27  ? 119 PRO c CB  1 
ATOM 3481 C CG  . PRO D 3 120 ? 120.254 136.289 112.692 1.00 55.27  ? 119 PRO c CG  1 
ATOM 3482 C CD  . PRO D 3 120 ? 120.612 134.846 112.814 1.00 55.27  ? 119 PRO c CD  1 
ATOM 3483 N N   . LEU D 3 121 ? 119.680 135.543 109.262 1.00 55.04  ? 120 LEU c N   1 
ATOM 3484 C CA  . LEU D 3 121 ? 119.666 135.916 107.851 1.00 55.04  ? 120 LEU c CA  1 
ATOM 3485 C C   . LEU D 3 121 ? 118.889 134.904 107.016 1.00 55.04  ? 120 LEU c C   1 
ATOM 3486 O O   . LEU D 3 121 ? 117.989 135.273 106.253 1.00 55.04  ? 120 LEU c O   1 
ATOM 3487 C CB  . LEU D 3 121 ? 121.098 136.053 107.336 1.00 55.04  ? 120 LEU c CB  1 
ATOM 3488 C CG  . LEU D 3 121 ? 121.255 136.449 105.869 1.00 55.04  ? 120 LEU c CG  1 
ATOM 3489 C CD1 . LEU D 3 121 ? 120.627 137.808 105.614 1.00 55.04  ? 120 LEU c CD1 1 
ATOM 3490 C CD2 . LEU D 3 121 ? 122.720 136.449 105.471 1.00 55.04  ? 120 LEU c CD2 1 
ATOM 3491 N N   . LEU D 3 122 ? 119.211 133.617 107.159 1.00 49.73  ? 121 LEU c N   1 
ATOM 3492 C CA  . LEU D 3 122 ? 118.543 132.599 106.352 1.00 49.73  ? 121 LEU c CA  1 
ATOM 3493 C C   . LEU D 3 122 ? 117.098 132.393 106.789 1.00 49.73  ? 121 LEU c C   1 
ATOM 3494 O O   . LEU D 3 122 ? 116.206 132.239 105.944 1.00 49.73  ? 121 LEU c O   1 
ATOM 3495 C CB  . LEU D 3 122 ? 119.315 131.282 106.415 1.00 49.73  ? 121 LEU c CB  1 
ATOM 3496 C CG  . LEU D 3 122 ? 120.364 131.039 105.327 1.00 49.73  ? 121 LEU c CG  1 
ATOM 3497 C CD1 . LEU D 3 122 ? 119.695 130.926 103.968 1.00 49.73  ? 121 LEU c CD1 1 
ATOM 3498 C CD2 . LEU D 3 122 ? 121.423 132.129 105.315 1.00 49.73  ? 121 LEU c CD2 1 
ATOM 3499 N N   . ILE D 3 123 ? 116.843 132.375 108.100 1.00 51.38  ? 122 ILE c N   1 
ATOM 3500 C CA  . ILE D 3 123 ? 115.479 132.174 108.574 1.00 51.38  ? 122 ILE c CA  1 
ATOM 3501 C C   . ILE D 3 123 ? 114.590 133.357 108.230 1.00 51.38  ? 122 ILE c C   1 
ATOM 3502 O O   . ILE D 3 123 ? 113.361 133.235 108.268 1.00 51.38  ? 122 ILE c O   1 
ATOM 3503 C CB  . ILE D 3 123 ? 115.443 131.905 110.090 1.00 51.38  ? 122 ILE c CB  1 
ATOM 3504 C CG1 . ILE D 3 123 ? 115.598 133.208 110.873 1.00 51.38  ? 122 ILE c CG1 1 
ATOM 3505 C CG2 . ILE D 3 123 ? 116.518 130.909 110.481 1.00 51.38  ? 122 ILE c CG2 1 
ATOM 3506 C CD1 . ILE D 3 123 ? 115.600 133.017 112.373 1.00 51.38  ? 122 ILE c CD1 1 
ATOM 3507 N N   . ASP D 3 124 ? 115.175 134.508 107.901 1.00 55.09  ? 123 ASP c N   1 
ATOM 3508 C CA  . ASP D 3 124 ? 114.386 135.640 107.438 1.00 55.09  ? 123 ASP c CA  1 
ATOM 3509 C C   . ASP D 3 124 ? 114.240 135.625 105.920 1.00 55.09  ? 123 ASP c C   1 
ATOM 3510 O O   . ASP D 3 124 ? 113.172 135.958 105.397 1.00 55.09  ? 123 ASP c O   1 
ATOM 3511 C CB  . ASP D 3 124 ? 115.034 136.948 107.905 1.00 55.09  ? 123 ASP c CB  1 
ATOM 3512 C CG  . ASP D 3 124 ? 114.163 138.169 107.652 1.00 55.09  ? 123 ASP c CG  1 
ATOM 3513 O OD1 . ASP D 3 124 ? 113.060 138.032 107.085 1.00 55.09  ? 123 ASP c OD1 1 
ATOM 3514 O OD2 . ASP D 3 124 ? 114.589 139.280 108.030 1.00 55.09  ? 123 ASP c OD2 1 
ATOM 3515 N N   . ALA D 3 125 ? 115.288 135.219 105.202 1.00 52.06  ? 124 ALA c N   1 
ATOM 3516 C CA  . ALA D 3 125 ? 115.240 135.197 103.747 1.00 52.06  ? 124 ALA c CA  1 
ATOM 3517 C C   . ALA D 3 125 ? 114.415 134.045 103.190 1.00 52.06  ? 124 ALA c C   1 
ATOM 3518 O O   . ALA D 3 125 ? 113.992 134.114 102.032 1.00 52.06  ? 124 ALA c O   1 
ATOM 3519 C CB  . ALA D 3 125 ? 116.657 135.129 103.174 1.00 52.06  ? 124 ALA c CB  1 
ATOM 3520 N N   . ILE D 3 126 ? 114.181 132.994 103.968 1.00 50.26  ? 125 ILE c N   1 
ATOM 3521 C CA  . ILE D 3 126 ? 113.412 131.842 103.501 1.00 50.26  ? 125 ILE c CA  1 
ATOM 3522 C C   . ILE D 3 126 ? 111.964 131.903 103.969 1.00 50.26  ? 125 ILE c C   1 
ATOM 3523 O O   . ILE D 3 126 ? 111.041 131.730 103.174 1.00 50.26  ? 125 ILE c O   1 
ATOM 3524 C CB  . ILE D 3 126 ? 114.089 130.527 103.947 1.00 50.26  ? 125 ILE c CB  1 
ATOM 3525 C CG1 . ILE D 3 126 ? 115.472 130.399 103.311 1.00 50.26  ? 125 ILE c CG1 1 
ATOM 3526 C CG2 . ILE D 3 126 ? 113.226 129.336 103.577 1.00 50.26  ? 125 ILE c CG2 1 
ATOM 3527 C CD1 . ILE D 3 126 ? 116.307 129.279 103.886 1.00 50.26  ? 125 ILE c CD1 1 
ATOM 3528 N N   . ASP D 3 127 ? 111.745 132.141 105.264 1.00 54.73  ? 126 ASP c N   1 
ATOM 3529 C CA  . ASP D 3 127 ? 110.383 132.151 105.793 1.00 54.73  ? 126 ASP c CA  1 
ATOM 3530 C C   . ASP D 3 127 ? 109.560 133.292 105.207 1.00 54.73  ? 126 ASP c C   1 
ATOM 3531 O O   . ASP D 3 127 ? 108.382 133.108 104.882 1.00 54.73  ? 126 ASP c O   1 
ATOM 3532 C CB  . ASP D 3 127 ? 110.413 132.240 107.317 1.00 54.73  ? 126 ASP c CB  1 
ATOM 3533 C CG  . ASP D 3 127 ? 110.817 130.934 107.968 1.00 54.73  ? 126 ASP c CG  1 
ATOM 3534 O OD1 . ASP D 3 127 ? 111.524 130.139 107.314 1.00 54.73  ? 126 ASP c OD1 1 
ATOM 3535 O OD2 . ASP D 3 127 ? 110.431 130.702 109.133 1.00 54.73  ? 126 ASP c OD2 1 
ATOM 3536 N N   . GLN D 3 128 ? 110.157 134.475 105.065 1.00 58.59  ? 127 GLN c N   1 
ATOM 3537 C CA  . GLN D 3 128 ? 109.444 135.639 104.559 1.00 58.59  ? 127 GLN c CA  1 
ATOM 3538 C C   . GLN D 3 128 ? 109.749 135.950 103.100 1.00 58.59  ? 127 GLN c C   1 
ATOM 3539 O O   . GLN D 3 128 ? 109.080 136.811 102.518 1.00 58.59  ? 127 GLN c O   1 
ATOM 3540 C CB  . GLN D 3 128 ? 109.763 136.868 105.418 1.00 58.59  ? 127 GLN c CB  1 
ATOM 3541 C CG  . GLN D 3 128 ? 108.723 137.160 106.485 1.00 58.59  ? 127 GLN c CG  1 
ATOM 3542 C CD  . GLN D 3 128 ? 108.937 136.345 107.744 1.00 58.59  ? 127 GLN c CD  1 
ATOM 3543 O OE1 . GLN D 3 128 ? 110.069 136.144 108.182 1.00 58.59  ? 127 GLN c OE1 1 
ATOM 3544 N NE2 . GLN D 3 128 ? 107.846 135.872 108.334 1.00 58.59  ? 127 GLN c NE2 1 
ATOM 3545 N N   . LEU D 3 129 ? 110.734 135.277 102.503 1.00 53.43  ? 128 LEU c N   1 
ATOM 3546 C CA  . LEU D 3 129 ? 111.077 135.451 101.090 1.00 53.43  ? 128 LEU c CA  1 
ATOM 3547 C C   . LEU D 3 129 ? 111.427 136.901 100.764 1.00 53.43  ? 128 LEU c C   1 
ATOM 3548 O O   . LEU D 3 129 ? 111.068 137.421 99.706  1.00 53.43  ? 128 LEU c O   1 
ATOM 3549 C CB  . LEU D 3 129 ? 109.951 134.953 100.181 1.00 53.43  ? 128 LEU c CB  1 
ATOM 3550 C CG  . LEU D 3 129 ? 109.770 133.440 100.073 1.00 53.43  ? 128 LEU c CG  1 
ATOM 3551 C CD1 . LEU D 3 129 ? 108.430 133.111 99.437  1.00 53.43  ? 128 LEU c CD1 1 
ATOM 3552 C CD2 . LEU D 3 129 ? 110.907 132.820 99.280  1.00 53.43  ? 128 LEU c CD2 1 
ATOM 3553 N N   . ASN D 3 130 ? 112.136 137.565 101.677 1.00 57.02  ? 129 ASN c N   1 
ATOM 3554 C CA  . ASN D 3 130 ? 112.586 138.927 101.433 1.00 57.02  ? 129 ASN c CA  1 
ATOM 3555 C C   . ASN D 3 130 ? 114.068 138.957 101.086 1.00 57.02  ? 129 ASN c C   1 
ATOM 3556 O O   . ASN D 3 130 ? 114.881 138.345 101.794 1.00 57.02  ? 129 ASN c O   1 
ATOM 3557 C CB  . ASN D 3 130 ? 112.273 139.834 102.627 1.00 57.02  ? 129 ASN c CB  1 
ATOM 3558 C CG  . ASN D 3 130 ? 112.917 139.380 103.933 1.00 57.02  ? 129 ASN c CG  1 
ATOM 3559 O OD1 . ASN D 3 130 ? 113.689 138.429 103.982 1.00 57.02  ? 129 ASN c OD1 1 
ATOM 3560 N ND2 . ASN D 3 130 ? 112.586 140.080 105.011 1.00 57.02  ? 129 ASN c ND2 1 
ATOM 3561 N N   . PRO D 3 131 ? 114.455 139.592 99.981  1.00 56.34  ? 130 PRO c N   1 
ATOM 3562 C CA  . PRO D 3 131 ? 115.874 139.625 99.610  1.00 56.34  ? 130 PRO c CA  1 
ATOM 3563 C C   . PRO D 3 131 ? 116.705 140.388 100.630 1.00 56.34  ? 130 PRO c C   1 
ATOM 3564 O O   . PRO D 3 131 ? 116.246 141.360 101.232 1.00 56.34  ? 130 PRO c O   1 
ATOM 3565 C CB  . PRO D 3 131 ? 115.868 140.331 98.248  1.00 56.34  ? 130 PRO c CB  1 
ATOM 3566 C CG  . PRO D 3 131 ? 114.571 141.069 98.201  1.00 56.34  ? 130 PRO c CG  1 
ATOM 3567 C CD  . PRO D 3 131 ? 113.601 140.234 98.970  1.00 56.34  ? 130 PRO c CD  1 
ATOM 3568 N N   . ALA D 3 132 ? 117.939 139.932 100.820 1.00 63.12  ? 131 ALA c N   1 
ATOM 3569 C CA  . ALA D 3 132 ? 118.879 140.627 101.687 1.00 63.12  ? 131 ALA c CA  1 
ATOM 3570 C C   . ALA D 3 132 ? 119.481 141.820 100.959 1.00 63.12  ? 131 ALA c C   1 
ATOM 3571 O O   . ALA D 3 132 ? 119.761 141.757 99.759  1.00 63.12  ? 131 ALA c O   1 
ATOM 3572 C CB  . ALA D 3 132 ? 119.985 139.679 102.147 1.00 63.12  ? 131 ALA c CB  1 
ATOM 3573 N N   . TYR D 3 133 ? 119.676 142.912 101.690 1.00 70.79  ? 132 TYR c N   1 
ATOM 3574 C CA  . TYR D 3 133 ? 120.237 144.124 101.107 1.00 70.79  ? 132 TYR c CA  1 
ATOM 3575 C C   . TYR D 3 133 ? 121.232 144.780 102.056 1.00 70.79  ? 132 TYR c C   1 
ATOM 3576 O O   . TYR D 3 133 ? 121.628 145.928 101.858 1.00 70.79  ? 132 TYR c O   1 
ATOM 3577 C CB  . TYR D 3 133 ? 119.125 145.112 100.744 1.00 70.79  ? 132 TYR c CB  1 
ATOM 3578 C CG  . TYR D 3 133 ? 118.317 145.599 101.927 1.00 70.79  ? 132 TYR c CG  1 
ATOM 3579 C CD1 . TYR D 3 133 ? 117.281 144.837 102.448 1.00 70.79  ? 132 TYR c CD1 1 
ATOM 3580 C CD2 . TYR D 3 133 ? 118.586 146.827 102.516 1.00 70.79  ? 132 TYR c CD2 1 
ATOM 3581 C CE1 . TYR D 3 133 ? 116.541 145.279 103.526 1.00 70.79  ? 132 TYR c CE1 1 
ATOM 3582 C CE2 . TYR D 3 133 ? 117.850 147.278 103.594 1.00 70.79  ? 132 TYR c CE2 1 
ATOM 3583 C CZ  . TYR D 3 133 ? 116.829 146.500 104.094 1.00 70.79  ? 132 TYR c CZ  1 
ATOM 3584 O OH  . TYR D 3 133 ? 116.093 146.944 105.168 1.00 70.79  ? 132 TYR c OH  1 
# 
