data_8W5R
# 
_entry.id   8W5R 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8W5R         pdb_00008w5r 10.2210/pdb8w5r/pdb 
WWPDB D_1300040615 ?            ?                   
EMDB  EMD-37302    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-02-26 ? 
2 'EM metadata'     1 0 2025-02-26 ? 
3 'Half map'        1 0 2025-02-26 1 
4 'Half map'        1 0 2025-02-26 2 
5 Image             1 0 2025-02-26 ? 
6 'Primary map'     1 0 2025-02-26 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Half map'        repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 Image             repository 'Initial release' ? ? 
6 6 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8W5R 
_pdbx_database_status.recvd_initial_deposition_date   2023-08-27 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure of Qb-Ab53' 
_pdbx_database_related.db_id          EMD-37302 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              zhup@ibp.ac.cn 
_pdbx_contact_author.name_first         Ping 
_pdbx_contact_author.name_last          Zhu 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-2648-3170 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Bao, K.Y.' 1 ? 
'Li, R.H.'  2 ? 
'Hua, Z.L.' 3 ? 
'Hou, B.D.' 4 ? 
'Zhu, P.'   5 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Cell Rep' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2211-1247 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            44 
_citation.language                  ? 
_citation.page_first                115334 
_citation.page_last                 115334 
_citation.title                     
'Competition propels, rather than limits, the success of low-affinity B cells in the germinal center response.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.celrep.2025.115334 
_citation.pdbx_database_id_PubMed   39955776 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Li, R.'  1 ? 
primary 'Bao, K.' 2 ? 
primary 'Liu, C.' 3 ? 
primary 'Ma, X.'  4 ? 
primary 'Hua, Z.' 5 ? 
primary 'Zhu, P.' 6 ? 
primary 'Hou, B.' 7 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'Minor capsid protein A1' 14268.071 3 ? ? ? ? 
2 polymer man 'Heavy chain of Ab53'     13956.570 1 ? ? ? ? 
3 polymer man 'Light chain of Ab53'     12111.401 1 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Qb coat protein' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MAKLETVTLGNIGKDGKQTLVLNPRGVNPTNGVASLSQAGAVPALEKRVTVSVSQPSRNRKNYKVQVKIQNPTACTANGS
CDPSVTRQAYADVTFSFTQYSTDEERAFVRTELAALLASPLLIDAIDQLNPAY
;
;MAKLETVTLGNIGKDGKQTLVLNPRGVNPTNGVASLSQAGAVPALEKRVTVSVSQPSRNRKNYKVQVKIQNPTACTANGS
CDPSVTRQAYADVTFSFTQYSTDEERAFVRTELAALLASPLLIDAIDQLNPAY
;
A,B,C ? 
2 'polypeptide(L)' no no 
;VHSQVQLQQPGTELVKPGASVKLSCKASGYTFTNYWMHWVKQRPGQGLEWIGMIHPDSGTTNYNEKFKSKATLTVDKSSN
TAYMQLSSLTSEDSAVYYCARGVFYINYYAMDYWGQGTSVSVSSA
;
;VHSQVQLQQPGTELVKPGASVKLSCKASGYTFTNYWMHWVKQRPGQGLEWIGMIHPDSGTTNYNEKFKSKATLTVDKSSN
TAYMQLSSLTSEDSAVYYCARGVFYINYYAMDYWGQGTSVSVSSA
;
H     ? 
3 'polypeptide(L)' no no 
;VHSDIQMTQSPASLSASVGETVTITCRASGNIHYFLAWYQQKQGKSPQLLVYHAETLADGVPSRFSGSGSGTQYSLKINS
LQPEDFGNYYCQHFWSTPYTFGGGTKLEIK
;
;VHSDIQMTQSPASLSASVGETVTITCRASGNIHYFLAWYQQKQGKSPQLLVYHAETLADGVPSRFSGSGSGTQYSLKINS
LQPEDFGNYYCQHFWSTPYTFGGGTKLEIK
;
L     ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ALA n 
1 3   LYS n 
1 4   LEU n 
1 5   GLU n 
1 6   THR n 
1 7   VAL n 
1 8   THR n 
1 9   LEU n 
1 10  GLY n 
1 11  ASN n 
1 12  ILE n 
1 13  GLY n 
1 14  LYS n 
1 15  ASP n 
1 16  GLY n 
1 17  LYS n 
1 18  GLN n 
1 19  THR n 
1 20  LEU n 
1 21  VAL n 
1 22  LEU n 
1 23  ASN n 
1 24  PRO n 
1 25  ARG n 
1 26  GLY n 
1 27  VAL n 
1 28  ASN n 
1 29  PRO n 
1 30  THR n 
1 31  ASN n 
1 32  GLY n 
1 33  VAL n 
1 34  ALA n 
1 35  SER n 
1 36  LEU n 
1 37  SER n 
1 38  GLN n 
1 39  ALA n 
1 40  GLY n 
1 41  ALA n 
1 42  VAL n 
1 43  PRO n 
1 44  ALA n 
1 45  LEU n 
1 46  GLU n 
1 47  LYS n 
1 48  ARG n 
1 49  VAL n 
1 50  THR n 
1 51  VAL n 
1 52  SER n 
1 53  VAL n 
1 54  SER n 
1 55  GLN n 
1 56  PRO n 
1 57  SER n 
1 58  ARG n 
1 59  ASN n 
1 60  ARG n 
1 61  LYS n 
1 62  ASN n 
1 63  TYR n 
1 64  LYS n 
1 65  VAL n 
1 66  GLN n 
1 67  VAL n 
1 68  LYS n 
1 69  ILE n 
1 70  GLN n 
1 71  ASN n 
1 72  PRO n 
1 73  THR n 
1 74  ALA n 
1 75  CYS n 
1 76  THR n 
1 77  ALA n 
1 78  ASN n 
1 79  GLY n 
1 80  SER n 
1 81  CYS n 
1 82  ASP n 
1 83  PRO n 
1 84  SER n 
1 85  VAL n 
1 86  THR n 
1 87  ARG n 
1 88  GLN n 
1 89  ALA n 
1 90  TYR n 
1 91  ALA n 
1 92  ASP n 
1 93  VAL n 
1 94  THR n 
1 95  PHE n 
1 96  SER n 
1 97  PHE n 
1 98  THR n 
1 99  GLN n 
1 100 TYR n 
1 101 SER n 
1 102 THR n 
1 103 ASP n 
1 104 GLU n 
1 105 GLU n 
1 106 ARG n 
1 107 ALA n 
1 108 PHE n 
1 109 VAL n 
1 110 ARG n 
1 111 THR n 
1 112 GLU n 
1 113 LEU n 
1 114 ALA n 
1 115 ALA n 
1 116 LEU n 
1 117 LEU n 
1 118 ALA n 
1 119 SER n 
1 120 PRO n 
1 121 LEU n 
1 122 LEU n 
1 123 ILE n 
1 124 ASP n 
1 125 ALA n 
1 126 ILE n 
1 127 ASP n 
1 128 GLN n 
1 129 LEU n 
1 130 ASN n 
1 131 PRO n 
1 132 ALA n 
1 133 TYR n 
2 1   VAL n 
2 2   HIS n 
2 3   SER n 
2 4   GLN n 
2 5   VAL n 
2 6   GLN n 
2 7   LEU n 
2 8   GLN n 
2 9   GLN n 
2 10  PRO n 
2 11  GLY n 
2 12  THR n 
2 13  GLU n 
2 14  LEU n 
2 15  VAL n 
2 16  LYS n 
2 17  PRO n 
2 18  GLY n 
2 19  ALA n 
2 20  SER n 
2 21  VAL n 
2 22  LYS n 
2 23  LEU n 
2 24  SER n 
2 25  CYS n 
2 26  LYS n 
2 27  ALA n 
2 28  SER n 
2 29  GLY n 
2 30  TYR n 
2 31  THR n 
2 32  PHE n 
2 33  THR n 
2 34  ASN n 
2 35  TYR n 
2 36  TRP n 
2 37  MET n 
2 38  HIS n 
2 39  TRP n 
2 40  VAL n 
2 41  LYS n 
2 42  GLN n 
2 43  ARG n 
2 44  PRO n 
2 45  GLY n 
2 46  GLN n 
2 47  GLY n 
2 48  LEU n 
2 49  GLU n 
2 50  TRP n 
2 51  ILE n 
2 52  GLY n 
2 53  MET n 
2 54  ILE n 
2 55  HIS n 
2 56  PRO n 
2 57  ASP n 
2 58  SER n 
2 59  GLY n 
2 60  THR n 
2 61  THR n 
2 62  ASN n 
2 63  TYR n 
2 64  ASN n 
2 65  GLU n 
2 66  LYS n 
2 67  PHE n 
2 68  LYS n 
2 69  SER n 
2 70  LYS n 
2 71  ALA n 
2 72  THR n 
2 73  LEU n 
2 74  THR n 
2 75  VAL n 
2 76  ASP n 
2 77  LYS n 
2 78  SER n 
2 79  SER n 
2 80  ASN n 
2 81  THR n 
2 82  ALA n 
2 83  TYR n 
2 84  MET n 
2 85  GLN n 
2 86  LEU n 
2 87  SER n 
2 88  SER n 
2 89  LEU n 
2 90  THR n 
2 91  SER n 
2 92  GLU n 
2 93  ASP n 
2 94  SER n 
2 95  ALA n 
2 96  VAL n 
2 97  TYR n 
2 98  TYR n 
2 99  CYS n 
2 100 ALA n 
2 101 ARG n 
2 102 GLY n 
2 103 VAL n 
2 104 PHE n 
2 105 TYR n 
2 106 ILE n 
2 107 ASN n 
2 108 TYR n 
2 109 TYR n 
2 110 ALA n 
2 111 MET n 
2 112 ASP n 
2 113 TYR n 
2 114 TRP n 
2 115 GLY n 
2 116 GLN n 
2 117 GLY n 
2 118 THR n 
2 119 SER n 
2 120 VAL n 
2 121 SER n 
2 122 VAL n 
2 123 SER n 
2 124 SER n 
2 125 ALA n 
3 1   VAL n 
3 2   HIS n 
3 3   SER n 
3 4   ASP n 
3 5   ILE n 
3 6   GLN n 
3 7   MET n 
3 8   THR n 
3 9   GLN n 
3 10  SER n 
3 11  PRO n 
3 12  ALA n 
3 13  SER n 
3 14  LEU n 
3 15  SER n 
3 16  ALA n 
3 17  SER n 
3 18  VAL n 
3 19  GLY n 
3 20  GLU n 
3 21  THR n 
3 22  VAL n 
3 23  THR n 
3 24  ILE n 
3 25  THR n 
3 26  CYS n 
3 27  ARG n 
3 28  ALA n 
3 29  SER n 
3 30  GLY n 
3 31  ASN n 
3 32  ILE n 
3 33  HIS n 
3 34  TYR n 
3 35  PHE n 
3 36  LEU n 
3 37  ALA n 
3 38  TRP n 
3 39  TYR n 
3 40  GLN n 
3 41  GLN n 
3 42  LYS n 
3 43  GLN n 
3 44  GLY n 
3 45  LYS n 
3 46  SER n 
3 47  PRO n 
3 48  GLN n 
3 49  LEU n 
3 50  LEU n 
3 51  VAL n 
3 52  TYR n 
3 53  HIS n 
3 54  ALA n 
3 55  GLU n 
3 56  THR n 
3 57  LEU n 
3 58  ALA n 
3 59  ASP n 
3 60  GLY n 
3 61  VAL n 
3 62  PRO n 
3 63  SER n 
3 64  ARG n 
3 65  PHE n 
3 66  SER n 
3 67  GLY n 
3 68  SER n 
3 69  GLY n 
3 70  SER n 
3 71  GLY n 
3 72  THR n 
3 73  GLN n 
3 74  TYR n 
3 75  SER n 
3 76  LEU n 
3 77  LYS n 
3 78  ILE n 
3 79  ASN n 
3 80  SER n 
3 81  LEU n 
3 82  GLN n 
3 83  PRO n 
3 84  GLU n 
3 85  ASP n 
3 86  PHE n 
3 87  GLY n 
3 88  ASN n 
3 89  TYR n 
3 90  TYR n 
3 91  CYS n 
3 92  GLN n 
3 93  HIS n 
3 94  PHE n 
3 95  TRP n 
3 96  SER n 
3 97  THR n 
3 98  PRO n 
3 99  TYR n 
3 100 THR n 
3 101 PHE n 
3 102 GLY n 
3 103 GLY n 
3 104 GLY n 
3 105 THR n 
3 106 LYS n 
3 107 LEU n 
3 108 GLU n 
3 109 ILE n 
3 110 LYS n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 133 ? ? ? ? ? ? ? ? ? 'Escherichia phage Qbeta' 2789016 ? ? ? ? ? ? ? ? 'Escherichia coli' 562  
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 125 ? ? ? ? ? ? ? ? ? 'Mus musculus'            10090   ? ? ? ? ? ? ? ? 'Homo sapiens'     9606 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 110 ? ? ? ? ? ? ? ? ? 'Mus musculus'            10090   ? ? ? ? ? ? ? ? 'Homo sapiens'     9606 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   0   ?   ?   ?   A . n 
A 1 2   ALA 2   1   1   ALA ALA A . n 
A 1 3   LYS 3   2   2   LYS LYS A . n 
A 1 4   LEU 4   3   3   LEU LEU A . n 
A 1 5   GLU 5   4   4   GLU GLU A . n 
A 1 6   THR 6   5   5   THR THR A . n 
A 1 7   VAL 7   6   6   VAL VAL A . n 
A 1 8   THR 8   7   7   THR THR A . n 
A 1 9   LEU 9   8   8   LEU LEU A . n 
A 1 10  GLY 10  9   9   GLY GLY A . n 
A 1 11  ASN 11  10  10  ASN ASN A . n 
A 1 12  ILE 12  11  11  ILE ILE A . n 
A 1 13  GLY 13  12  12  GLY GLY A . n 
A 1 14  LYS 14  13  13  LYS LYS A . n 
A 1 15  ASP 15  14  14  ASP ASP A . n 
A 1 16  GLY 16  15  15  GLY GLY A . n 
A 1 17  LYS 17  16  16  LYS LYS A . n 
A 1 18  GLN 18  17  17  GLN GLN A . n 
A 1 19  THR 19  18  18  THR THR A . n 
A 1 20  LEU 20  19  19  LEU LEU A . n 
A 1 21  VAL 21  20  20  VAL VAL A . n 
A 1 22  LEU 22  21  21  LEU LEU A . n 
A 1 23  ASN 23  22  22  ASN ASN A . n 
A 1 24  PRO 24  23  23  PRO PRO A . n 
A 1 25  ARG 25  24  24  ARG ARG A . n 
A 1 26  GLY 26  25  25  GLY GLY A . n 
A 1 27  VAL 27  26  26  VAL VAL A . n 
A 1 28  ASN 28  27  27  ASN ASN A . n 
A 1 29  PRO 29  28  28  PRO PRO A . n 
A 1 30  THR 30  29  29  THR THR A . n 
A 1 31  ASN 31  30  30  ASN ASN A . n 
A 1 32  GLY 32  31  31  GLY GLY A . n 
A 1 33  VAL 33  32  32  VAL VAL A . n 
A 1 34  ALA 34  33  33  ALA ALA A . n 
A 1 35  SER 35  34  34  SER SER A . n 
A 1 36  LEU 36  35  35  LEU LEU A . n 
A 1 37  SER 37  36  36  SER SER A . n 
A 1 38  GLN 38  37  37  GLN GLN A . n 
A 1 39  ALA 39  38  38  ALA ALA A . n 
A 1 40  GLY 40  39  39  GLY GLY A . n 
A 1 41  ALA 41  40  40  ALA ALA A . n 
A 1 42  VAL 42  41  41  VAL VAL A . n 
A 1 43  PRO 43  42  42  PRO PRO A . n 
A 1 44  ALA 44  43  43  ALA ALA A . n 
A 1 45  LEU 45  44  44  LEU LEU A . n 
A 1 46  GLU 46  45  45  GLU GLU A . n 
A 1 47  LYS 47  46  46  LYS LYS A . n 
A 1 48  ARG 48  47  47  ARG ARG A . n 
A 1 49  VAL 49  48  48  VAL VAL A . n 
A 1 50  THR 50  49  49  THR THR A . n 
A 1 51  VAL 51  50  50  VAL VAL A . n 
A 1 52  SER 52  51  51  SER SER A . n 
A 1 53  VAL 53  52  52  VAL VAL A . n 
A 1 54  SER 54  53  53  SER SER A . n 
A 1 55  GLN 55  54  54  GLN GLN A . n 
A 1 56  PRO 56  55  55  PRO PRO A . n 
A 1 57  SER 57  56  56  SER SER A . n 
A 1 58  ARG 58  57  57  ARG ARG A . n 
A 1 59  ASN 59  58  58  ASN ASN A . n 
A 1 60  ARG 60  59  59  ARG ARG A . n 
A 1 61  LYS 61  60  60  LYS LYS A . n 
A 1 62  ASN 62  61  61  ASN ASN A . n 
A 1 63  TYR 63  62  62  TYR TYR A . n 
A 1 64  LYS 64  63  63  LYS LYS A . n 
A 1 65  VAL 65  64  64  VAL VAL A . n 
A 1 66  GLN 66  65  65  GLN GLN A . n 
A 1 67  VAL 67  66  66  VAL VAL A . n 
A 1 68  LYS 68  67  67  LYS LYS A . n 
A 1 69  ILE 69  68  68  ILE ILE A . n 
A 1 70  GLN 70  69  69  GLN GLN A . n 
A 1 71  ASN 71  70  70  ASN ASN A . n 
A 1 72  PRO 72  71  71  PRO PRO A . n 
A 1 73  THR 73  72  72  THR THR A . n 
A 1 74  ALA 74  73  73  ALA ALA A . n 
A 1 75  CYS 75  74  74  CYS CYS A . n 
A 1 76  THR 76  75  75  THR THR A . n 
A 1 77  ALA 77  76  76  ALA ALA A . n 
A 1 78  ASN 78  77  ?   ?   ?   A . n 
A 1 79  GLY 79  78  ?   ?   ?   A . n 
A 1 80  SER 80  79  79  SER SER A . n 
A 1 81  CYS 81  80  80  CYS CYS A . n 
A 1 82  ASP 82  81  81  ASP ASP A . n 
A 1 83  PRO 83  82  82  PRO PRO A . n 
A 1 84  SER 84  83  83  SER SER A . n 
A 1 85  VAL 85  84  84  VAL VAL A . n 
A 1 86  THR 86  85  85  THR THR A . n 
A 1 87  ARG 87  86  86  ARG ARG A . n 
A 1 88  GLN 88  87  87  GLN GLN A . n 
A 1 89  ALA 89  88  88  ALA ALA A . n 
A 1 90  TYR 90  89  89  TYR TYR A . n 
A 1 91  ALA 91  90  90  ALA ALA A . n 
A 1 92  ASP 92  91  91  ASP ASP A . n 
A 1 93  VAL 93  92  92  VAL VAL A . n 
A 1 94  THR 94  93  93  THR THR A . n 
A 1 95  PHE 95  94  94  PHE PHE A . n 
A 1 96  SER 96  95  95  SER SER A . n 
A 1 97  PHE 97  96  96  PHE PHE A . n 
A 1 98  THR 98  97  97  THR THR A . n 
A 1 99  GLN 99  98  98  GLN GLN A . n 
A 1 100 TYR 100 99  99  TYR TYR A . n 
A 1 101 SER 101 100 100 SER SER A . n 
A 1 102 THR 102 101 101 THR THR A . n 
A 1 103 ASP 103 102 102 ASP ASP A . n 
A 1 104 GLU 104 103 103 GLU GLU A . n 
A 1 105 GLU 105 104 104 GLU GLU A . n 
A 1 106 ARG 106 105 105 ARG ARG A . n 
A 1 107 ALA 107 106 106 ALA ALA A . n 
A 1 108 PHE 108 107 107 PHE PHE A . n 
A 1 109 VAL 109 108 108 VAL VAL A . n 
A 1 110 ARG 110 109 109 ARG ARG A . n 
A 1 111 THR 111 110 110 THR THR A . n 
A 1 112 GLU 112 111 111 GLU GLU A . n 
A 1 113 LEU 113 112 112 LEU LEU A . n 
A 1 114 ALA 114 113 113 ALA ALA A . n 
A 1 115 ALA 115 114 114 ALA ALA A . n 
A 1 116 LEU 116 115 115 LEU LEU A . n 
A 1 117 LEU 117 116 116 LEU LEU A . n 
A 1 118 ALA 118 117 117 ALA ALA A . n 
A 1 119 SER 119 118 118 SER SER A . n 
A 1 120 PRO 120 119 119 PRO PRO A . n 
A 1 121 LEU 121 120 120 LEU LEU A . n 
A 1 122 LEU 122 121 121 LEU LEU A . n 
A 1 123 ILE 123 122 122 ILE ILE A . n 
A 1 124 ASP 124 123 123 ASP ASP A . n 
A 1 125 ALA 125 124 124 ALA ALA A . n 
A 1 126 ILE 126 125 125 ILE ILE A . n 
A 1 127 ASP 127 126 126 ASP ASP A . n 
A 1 128 GLN 128 127 127 GLN GLN A . n 
A 1 129 LEU 129 128 128 LEU LEU A . n 
A 1 130 ASN 130 129 129 ASN ASN A . n 
A 1 131 PRO 131 130 130 PRO PRO A . n 
A 1 132 ALA 132 131 131 ALA ALA A . n 
A 1 133 TYR 133 132 132 TYR TYR A . n 
B 1 1   MET 1   0   ?   ?   ?   B . n 
B 1 2   ALA 2   1   1   ALA ALA B . n 
B 1 3   LYS 3   2   2   LYS LYS B . n 
B 1 4   LEU 4   3   3   LEU LEU B . n 
B 1 5   GLU 5   4   4   GLU GLU B . n 
B 1 6   THR 6   5   5   THR THR B . n 
B 1 7   VAL 7   6   6   VAL VAL B . n 
B 1 8   THR 8   7   7   THR THR B . n 
B 1 9   LEU 9   8   8   LEU LEU B . n 
B 1 10  GLY 10  9   9   GLY GLY B . n 
B 1 11  ASN 11  10  10  ASN ASN B . n 
B 1 12  ILE 12  11  11  ILE ILE B . n 
B 1 13  GLY 13  12  12  GLY GLY B . n 
B 1 14  LYS 14  13  13  LYS LYS B . n 
B 1 15  ASP 15  14  14  ASP ASP B . n 
B 1 16  GLY 16  15  15  GLY GLY B . n 
B 1 17  LYS 17  16  16  LYS LYS B . n 
B 1 18  GLN 18  17  17  GLN GLN B . n 
B 1 19  THR 19  18  18  THR THR B . n 
B 1 20  LEU 20  19  19  LEU LEU B . n 
B 1 21  VAL 21  20  20  VAL VAL B . n 
B 1 22  LEU 22  21  21  LEU LEU B . n 
B 1 23  ASN 23  22  22  ASN ASN B . n 
B 1 24  PRO 24  23  23  PRO PRO B . n 
B 1 25  ARG 25  24  24  ARG ARG B . n 
B 1 26  GLY 26  25  25  GLY GLY B . n 
B 1 27  VAL 27  26  26  VAL VAL B . n 
B 1 28  ASN 28  27  27  ASN ASN B . n 
B 1 29  PRO 29  28  28  PRO PRO B . n 
B 1 30  THR 30  29  29  THR THR B . n 
B 1 31  ASN 31  30  30  ASN ASN B . n 
B 1 32  GLY 32  31  31  GLY GLY B . n 
B 1 33  VAL 33  32  32  VAL VAL B . n 
B 1 34  ALA 34  33  33  ALA ALA B . n 
B 1 35  SER 35  34  34  SER SER B . n 
B 1 36  LEU 36  35  35  LEU LEU B . n 
B 1 37  SER 37  36  36  SER SER B . n 
B 1 38  GLN 38  37  37  GLN GLN B . n 
B 1 39  ALA 39  38  38  ALA ALA B . n 
B 1 40  GLY 40  39  39  GLY GLY B . n 
B 1 41  ALA 41  40  40  ALA ALA B . n 
B 1 42  VAL 42  41  41  VAL VAL B . n 
B 1 43  PRO 43  42  42  PRO PRO B . n 
B 1 44  ALA 44  43  43  ALA ALA B . n 
B 1 45  LEU 45  44  44  LEU LEU B . n 
B 1 46  GLU 46  45  45  GLU GLU B . n 
B 1 47  LYS 47  46  46  LYS LYS B . n 
B 1 48  ARG 48  47  47  ARG ARG B . n 
B 1 49  VAL 49  48  48  VAL VAL B . n 
B 1 50  THR 50  49  49  THR THR B . n 
B 1 51  VAL 51  50  50  VAL VAL B . n 
B 1 52  SER 52  51  51  SER SER B . n 
B 1 53  VAL 53  52  52  VAL VAL B . n 
B 1 54  SER 54  53  53  SER SER B . n 
B 1 55  GLN 55  54  54  GLN GLN B . n 
B 1 56  PRO 56  55  55  PRO PRO B . n 
B 1 57  SER 57  56  56  SER SER B . n 
B 1 58  ARG 58  57  57  ARG ARG B . n 
B 1 59  ASN 59  58  58  ASN ASN B . n 
B 1 60  ARG 60  59  59  ARG ARG B . n 
B 1 61  LYS 61  60  60  LYS LYS B . n 
B 1 62  ASN 62  61  61  ASN ASN B . n 
B 1 63  TYR 63  62  62  TYR TYR B . n 
B 1 64  LYS 64  63  63  LYS LYS B . n 
B 1 65  VAL 65  64  64  VAL VAL B . n 
B 1 66  GLN 66  65  65  GLN GLN B . n 
B 1 67  VAL 67  66  66  VAL VAL B . n 
B 1 68  LYS 68  67  67  LYS LYS B . n 
B 1 69  ILE 69  68  68  ILE ILE B . n 
B 1 70  GLN 70  69  69  GLN GLN B . n 
B 1 71  ASN 71  70  70  ASN ASN B . n 
B 1 72  PRO 72  71  71  PRO PRO B . n 
B 1 73  THR 73  72  72  THR THR B . n 
B 1 74  ALA 74  73  73  ALA ALA B . n 
B 1 75  CYS 75  74  74  CYS CYS B . n 
B 1 76  THR 76  75  75  THR THR B . n 
B 1 77  ALA 77  76  76  ALA ALA B . n 
B 1 78  ASN 78  77  ?   ?   ?   B . n 
B 1 79  GLY 79  78  ?   ?   ?   B . n 
B 1 80  SER 80  79  79  SER SER B . n 
B 1 81  CYS 81  80  80  CYS CYS B . n 
B 1 82  ASP 82  81  81  ASP ASP B . n 
B 1 83  PRO 83  82  82  PRO PRO B . n 
B 1 84  SER 84  83  83  SER SER B . n 
B 1 85  VAL 85  84  84  VAL VAL B . n 
B 1 86  THR 86  85  85  THR THR B . n 
B 1 87  ARG 87  86  86  ARG ARG B . n 
B 1 88  GLN 88  87  87  GLN GLN B . n 
B 1 89  ALA 89  88  88  ALA ALA B . n 
B 1 90  TYR 90  89  89  TYR TYR B . n 
B 1 91  ALA 91  90  90  ALA ALA B . n 
B 1 92  ASP 92  91  91  ASP ASP B . n 
B 1 93  VAL 93  92  92  VAL VAL B . n 
B 1 94  THR 94  93  93  THR THR B . n 
B 1 95  PHE 95  94  94  PHE PHE B . n 
B 1 96  SER 96  95  95  SER SER B . n 
B 1 97  PHE 97  96  96  PHE PHE B . n 
B 1 98  THR 98  97  97  THR THR B . n 
B 1 99  GLN 99  98  98  GLN GLN B . n 
B 1 100 TYR 100 99  99  TYR TYR B . n 
B 1 101 SER 101 100 100 SER SER B . n 
B 1 102 THR 102 101 101 THR THR B . n 
B 1 103 ASP 103 102 102 ASP ASP B . n 
B 1 104 GLU 104 103 103 GLU GLU B . n 
B 1 105 GLU 105 104 104 GLU GLU B . n 
B 1 106 ARG 106 105 105 ARG ARG B . n 
B 1 107 ALA 107 106 106 ALA ALA B . n 
B 1 108 PHE 108 107 107 PHE PHE B . n 
B 1 109 VAL 109 108 108 VAL VAL B . n 
B 1 110 ARG 110 109 109 ARG ARG B . n 
B 1 111 THR 111 110 110 THR THR B . n 
B 1 112 GLU 112 111 111 GLU GLU B . n 
B 1 113 LEU 113 112 112 LEU LEU B . n 
B 1 114 ALA 114 113 113 ALA ALA B . n 
B 1 115 ALA 115 114 114 ALA ALA B . n 
B 1 116 LEU 116 115 115 LEU LEU B . n 
B 1 117 LEU 117 116 116 LEU LEU B . n 
B 1 118 ALA 118 117 117 ALA ALA B . n 
B 1 119 SER 119 118 118 SER SER B . n 
B 1 120 PRO 120 119 119 PRO PRO B . n 
B 1 121 LEU 121 120 120 LEU LEU B . n 
B 1 122 LEU 122 121 121 LEU LEU B . n 
B 1 123 ILE 123 122 122 ILE ILE B . n 
B 1 124 ASP 124 123 123 ASP ASP B . n 
B 1 125 ALA 125 124 124 ALA ALA B . n 
B 1 126 ILE 126 125 125 ILE ILE B . n 
B 1 127 ASP 127 126 126 ASP ASP B . n 
B 1 128 GLN 128 127 127 GLN GLN B . n 
B 1 129 LEU 129 128 128 LEU LEU B . n 
B 1 130 ASN 130 129 129 ASN ASN B . n 
B 1 131 PRO 131 130 130 PRO PRO B . n 
B 1 132 ALA 132 131 131 ALA ALA B . n 
B 1 133 TYR 133 132 132 TYR TYR B . n 
C 2 1   VAL 1   1   ?   ?   ?   H . n 
C 2 2   HIS 2   2   ?   ?   ?   H . n 
C 2 3   SER 3   3   ?   ?   ?   H . n 
C 2 4   GLN 4   4   ?   ?   ?   H . n 
C 2 5   VAL 5   5   5   VAL VAL H . n 
C 2 6   GLN 6   6   6   GLN GLN H . n 
C 2 7   LEU 7   7   7   LEU LEU H . n 
C 2 8   GLN 8   8   8   GLN GLN H . n 
C 2 9   GLN 9   9   9   GLN GLN H . n 
C 2 10  PRO 10  10  10  PRO PRO H . n 
C 2 11  GLY 11  11  11  GLY GLY H . n 
C 2 12  THR 12  12  12  THR THR H . n 
C 2 13  GLU 13  13  13  GLU GLU H . n 
C 2 14  LEU 14  14  14  LEU LEU H . n 
C 2 15  VAL 15  15  15  VAL VAL H . n 
C 2 16  LYS 16  16  16  LYS LYS H . n 
C 2 17  PRO 17  17  17  PRO PRO H . n 
C 2 18  GLY 18  18  18  GLY GLY H . n 
C 2 19  ALA 19  19  19  ALA ALA H . n 
C 2 20  SER 20  20  20  SER SER H . n 
C 2 21  VAL 21  21  21  VAL VAL H . n 
C 2 22  LYS 22  22  22  LYS LYS H . n 
C 2 23  LEU 23  23  23  LEU LEU H . n 
C 2 24  SER 24  24  24  SER SER H . n 
C 2 25  CYS 25  25  25  CYS CYS H . n 
C 2 26  LYS 26  26  26  LYS LYS H . n 
C 2 27  ALA 27  27  27  ALA ALA H . n 
C 2 28  SER 28  28  28  SER SER H . n 
C 2 29  GLY 29  29  29  GLY GLY H . n 
C 2 30  TYR 30  30  30  TYR TYR H . n 
C 2 31  THR 31  31  31  THR THR H . n 
C 2 32  PHE 32  32  32  PHE PHE H . n 
C 2 33  THR 33  33  33  THR THR H . n 
C 2 34  ASN 34  34  34  ASN ASN H . n 
C 2 35  TYR 35  35  35  TYR TYR H . n 
C 2 36  TRP 36  36  36  TRP TRP H . n 
C 2 37  MET 37  37  37  MET MET H . n 
C 2 38  HIS 38  38  38  HIS HIS H . n 
C 2 39  TRP 39  39  39  TRP TRP H . n 
C 2 40  VAL 40  40  40  VAL VAL H . n 
C 2 41  LYS 41  41  41  LYS LYS H . n 
C 2 42  GLN 42  42  42  GLN GLN H . n 
C 2 43  ARG 43  43  43  ARG ARG H . n 
C 2 44  PRO 44  44  44  PRO PRO H . n 
C 2 45  GLY 45  45  45  GLY GLY H . n 
C 2 46  GLN 46  46  46  GLN GLN H . n 
C 2 47  GLY 47  47  47  GLY GLY H . n 
C 2 48  LEU 48  48  48  LEU LEU H . n 
C 2 49  GLU 49  49  49  GLU GLU H . n 
C 2 50  TRP 50  50  50  TRP TRP H . n 
C 2 51  ILE 51  51  51  ILE ILE H . n 
C 2 52  GLY 52  52  52  GLY GLY H . n 
C 2 53  MET 53  53  53  MET MET H . n 
C 2 54  ILE 54  54  54  ILE ILE H . n 
C 2 55  HIS 55  55  55  HIS HIS H . n 
C 2 56  PRO 56  56  56  PRO PRO H . n 
C 2 57  ASP 57  57  57  ASP ASP H . n 
C 2 58  SER 58  58  58  SER SER H . n 
C 2 59  GLY 59  59  59  GLY GLY H . n 
C 2 60  THR 60  60  60  THR THR H . n 
C 2 61  THR 61  61  61  THR THR H . n 
C 2 62  ASN 62  62  62  ASN ASN H . n 
C 2 63  TYR 63  63  63  TYR TYR H . n 
C 2 64  ASN 64  64  64  ASN ASN H . n 
C 2 65  GLU 65  65  65  GLU GLU H . n 
C 2 66  LYS 66  66  66  LYS LYS H . n 
C 2 67  PHE 67  67  67  PHE PHE H . n 
C 2 68  LYS 68  68  68  LYS LYS H . n 
C 2 69  SER 69  69  69  SER SER H . n 
C 2 70  LYS 70  70  70  LYS LYS H . n 
C 2 71  ALA 71  71  71  ALA ALA H . n 
C 2 72  THR 72  72  72  THR THR H . n 
C 2 73  LEU 73  73  73  LEU LEU H . n 
C 2 74  THR 74  74  74  THR THR H . n 
C 2 75  VAL 75  75  75  VAL VAL H . n 
C 2 76  ASP 76  76  76  ASP ASP H . n 
C 2 77  LYS 77  77  77  LYS LYS H . n 
C 2 78  SER 78  78  78  SER SER H . n 
C 2 79  SER 79  79  79  SER SER H . n 
C 2 80  ASN 80  80  80  ASN ASN H . n 
C 2 81  THR 81  81  81  THR THR H . n 
C 2 82  ALA 82  82  82  ALA ALA H . n 
C 2 83  TYR 83  83  83  TYR TYR H . n 
C 2 84  MET 84  84  84  MET MET H . n 
C 2 85  GLN 85  85  85  GLN GLN H . n 
C 2 86  LEU 86  86  86  LEU LEU H . n 
C 2 87  SER 87  87  87  SER SER H . n 
C 2 88  SER 88  88  88  SER SER H . n 
C 2 89  LEU 89  89  89  LEU LEU H . n 
C 2 90  THR 90  90  90  THR THR H . n 
C 2 91  SER 91  91  91  SER SER H . n 
C 2 92  GLU 92  92  92  GLU GLU H . n 
C 2 93  ASP 93  93  93  ASP ASP H . n 
C 2 94  SER 94  94  94  SER SER H . n 
C 2 95  ALA 95  95  95  ALA ALA H . n 
C 2 96  VAL 96  96  96  VAL VAL H . n 
C 2 97  TYR 97  97  97  TYR TYR H . n 
C 2 98  TYR 98  98  98  TYR TYR H . n 
C 2 99  CYS 99  99  99  CYS CYS H . n 
C 2 100 ALA 100 100 100 ALA ALA H . n 
C 2 101 ARG 101 101 101 ARG ARG H . n 
C 2 102 GLY 102 102 102 GLY GLY H . n 
C 2 103 VAL 103 103 103 VAL VAL H . n 
C 2 104 PHE 104 104 104 PHE PHE H . n 
C 2 105 TYR 105 105 105 TYR TYR H . n 
C 2 106 ILE 106 106 106 ILE ILE H . n 
C 2 107 ASN 107 107 107 ASN ASN H . n 
C 2 108 TYR 108 108 108 TYR TYR H . n 
C 2 109 TYR 109 109 109 TYR TYR H . n 
C 2 110 ALA 110 110 110 ALA ALA H . n 
C 2 111 MET 111 111 111 MET MET H . n 
C 2 112 ASP 112 112 112 ASP ASP H . n 
C 2 113 TYR 113 113 113 TYR TYR H . n 
C 2 114 TRP 114 114 114 TRP TRP H . n 
C 2 115 GLY 115 115 115 GLY GLY H . n 
C 2 116 GLN 116 116 116 GLN GLN H . n 
C 2 117 GLY 117 117 117 GLY GLY H . n 
C 2 118 THR 118 118 118 THR THR H . n 
C 2 119 SER 119 119 119 SER SER H . n 
C 2 120 VAL 120 120 120 VAL VAL H . n 
C 2 121 SER 121 121 121 SER SER H . n 
C 2 122 VAL 122 122 ?   ?   ?   H . n 
C 2 123 SER 123 123 ?   ?   ?   H . n 
C 2 124 SER 124 124 ?   ?   ?   H . n 
C 2 125 ALA 125 125 ?   ?   ?   H . n 
D 3 1   VAL 1   1   ?   ?   ?   L . n 
D 3 2   HIS 2   2   ?   ?   ?   L . n 
D 3 3   SER 3   3   ?   ?   ?   L . n 
D 3 4   ASP 4   4   ?   ?   ?   L . n 
D 3 5   ILE 5   5   5   ILE ILE L . n 
D 3 6   GLN 6   6   6   GLN GLN L . n 
D 3 7   MET 7   7   7   MET MET L . n 
D 3 8   THR 8   8   8   THR THR L . n 
D 3 9   GLN 9   9   9   GLN GLN L . n 
D 3 10  SER 10  10  10  SER SER L . n 
D 3 11  PRO 11  11  11  PRO PRO L . n 
D 3 12  ALA 12  12  12  ALA ALA L . n 
D 3 13  SER 13  13  13  SER SER L . n 
D 3 14  LEU 14  14  14  LEU LEU L . n 
D 3 15  SER 15  15  15  SER SER L . n 
D 3 16  ALA 16  16  16  ALA ALA L . n 
D 3 17  SER 17  17  17  SER SER L . n 
D 3 18  VAL 18  18  18  VAL VAL L . n 
D 3 19  GLY 19  19  19  GLY GLY L . n 
D 3 20  GLU 20  20  20  GLU GLU L . n 
D 3 21  THR 21  21  21  THR THR L . n 
D 3 22  VAL 22  22  22  VAL VAL L . n 
D 3 23  THR 23  23  23  THR THR L . n 
D 3 24  ILE 24  24  24  ILE ILE L . n 
D 3 25  THR 25  25  25  THR THR L . n 
D 3 26  CYS 26  26  26  CYS CYS L . n 
D 3 27  ARG 27  27  27  ARG ARG L . n 
D 3 28  ALA 28  28  28  ALA ALA L . n 
D 3 29  SER 29  29  29  SER SER L . n 
D 3 30  GLY 30  30  30  GLY GLY L . n 
D 3 31  ASN 31  31  31  ASN ASN L . n 
D 3 32  ILE 32  32  32  ILE ILE L . n 
D 3 33  HIS 33  33  33  HIS HIS L . n 
D 3 34  TYR 34  34  34  TYR TYR L . n 
D 3 35  PHE 35  35  35  PHE PHE L . n 
D 3 36  LEU 36  36  36  LEU LEU L . n 
D 3 37  ALA 37  37  37  ALA ALA L . n 
D 3 38  TRP 38  38  38  TRP TRP L . n 
D 3 39  TYR 39  39  39  TYR TYR L . n 
D 3 40  GLN 40  40  40  GLN GLN L . n 
D 3 41  GLN 41  41  41  GLN GLN L . n 
D 3 42  LYS 42  42  42  LYS LYS L . n 
D 3 43  GLN 43  43  43  GLN GLN L . n 
D 3 44  GLY 44  44  44  GLY GLY L . n 
D 3 45  LYS 45  45  45  LYS LYS L . n 
D 3 46  SER 46  46  46  SER SER L . n 
D 3 47  PRO 47  47  47  PRO PRO L . n 
D 3 48  GLN 48  48  48  GLN GLN L . n 
D 3 49  LEU 49  49  49  LEU LEU L . n 
D 3 50  LEU 50  50  50  LEU LEU L . n 
D 3 51  VAL 51  51  51  VAL VAL L . n 
D 3 52  TYR 52  52  52  TYR TYR L . n 
D 3 53  HIS 53  53  53  HIS HIS L . n 
D 3 54  ALA 54  54  54  ALA ALA L . n 
D 3 55  GLU 55  55  55  GLU GLU L . n 
D 3 56  THR 56  56  56  THR THR L . n 
D 3 57  LEU 57  57  57  LEU LEU L . n 
D 3 58  ALA 58  58  58  ALA ALA L . n 
D 3 59  ASP 59  59  59  ASP ASP L . n 
D 3 60  GLY 60  60  60  GLY GLY L . n 
D 3 61  VAL 61  61  61  VAL VAL L . n 
D 3 62  PRO 62  62  62  PRO PRO L . n 
D 3 63  SER 63  63  63  SER SER L . n 
D 3 64  ARG 64  64  64  ARG ARG L . n 
D 3 65  PHE 65  65  65  PHE PHE L . n 
D 3 66  SER 66  66  66  SER SER L . n 
D 3 67  GLY 67  67  67  GLY GLY L . n 
D 3 68  SER 68  68  68  SER SER L . n 
D 3 69  GLY 69  69  69  GLY GLY L . n 
D 3 70  SER 70  70  70  SER SER L . n 
D 3 71  GLY 71  71  71  GLY GLY L . n 
D 3 72  THR 72  72  72  THR THR L . n 
D 3 73  GLN 73  73  73  GLN GLN L . n 
D 3 74  TYR 74  74  74  TYR TYR L . n 
D 3 75  SER 75  75  75  SER SER L . n 
D 3 76  LEU 76  76  76  LEU LEU L . n 
D 3 77  LYS 77  77  77  LYS LYS L . n 
D 3 78  ILE 78  78  78  ILE ILE L . n 
D 3 79  ASN 79  79  79  ASN ASN L . n 
D 3 80  SER 80  80  80  SER SER L . n 
D 3 81  LEU 81  81  81  LEU LEU L . n 
D 3 82  GLN 82  82  82  GLN GLN L . n 
D 3 83  PRO 83  83  83  PRO PRO L . n 
D 3 84  GLU 84  84  84  GLU GLU L . n 
D 3 85  ASP 85  85  85  ASP ASP L . n 
D 3 86  PHE 86  86  86  PHE PHE L . n 
D 3 87  GLY 87  87  87  GLY GLY L . n 
D 3 88  ASN 88  88  88  ASN ASN L . n 
D 3 89  TYR 89  89  89  TYR TYR L . n 
D 3 90  TYR 90  90  90  TYR TYR L . n 
D 3 91  CYS 91  91  91  CYS CYS L . n 
D 3 92  GLN 92  92  92  GLN GLN L . n 
D 3 93  HIS 93  93  93  HIS HIS L . n 
D 3 94  PHE 94  94  94  PHE PHE L . n 
D 3 95  TRP 95  95  95  TRP TRP L . n 
D 3 96  SER 96  96  96  SER SER L . n 
D 3 97  THR 97  97  97  THR THR L . n 
D 3 98  PRO 98  98  98  PRO PRO L . n 
D 3 99  TYR 99  99  99  TYR TYR L . n 
D 3 100 THR 100 100 100 THR THR L . n 
D 3 101 PHE 101 101 101 PHE PHE L . n 
D 3 102 GLY 102 102 102 GLY GLY L . n 
D 3 103 GLY 103 103 103 GLY GLY L . n 
D 3 104 GLY 104 104 104 GLY GLY L . n 
D 3 105 THR 105 105 105 THR THR L . n 
D 3 106 LYS 106 106 106 LYS LYS L . n 
D 3 107 LEU 107 107 107 LEU LEU L . n 
D 3 108 GLU 108 108 ?   ?   ?   L . n 
D 3 109 ILE 109 109 ?   ?   ?   L . n 
D 3 110 LYS 110 110 ?   ?   ?   L . n 
E 1 1   MET 1   0   ?   ?   ?   C . n 
E 1 2   ALA 2   1   1   ALA ALA C . n 
E 1 3   LYS 3   2   2   LYS LYS C . n 
E 1 4   LEU 4   3   3   LEU LEU C . n 
E 1 5   GLU 5   4   4   GLU GLU C . n 
E 1 6   THR 6   5   5   THR THR C . n 
E 1 7   VAL 7   6   6   VAL VAL C . n 
E 1 8   THR 8   7   7   THR THR C . n 
E 1 9   LEU 9   8   8   LEU LEU C . n 
E 1 10  GLY 10  9   9   GLY GLY C . n 
E 1 11  ASN 11  10  10  ASN ASN C . n 
E 1 12  ILE 12  11  11  ILE ILE C . n 
E 1 13  GLY 13  12  12  GLY GLY C . n 
E 1 14  LYS 14  13  13  LYS LYS C . n 
E 1 15  ASP 15  14  14  ASP ASP C . n 
E 1 16  GLY 16  15  15  GLY GLY C . n 
E 1 17  LYS 17  16  16  LYS LYS C . n 
E 1 18  GLN 18  17  17  GLN GLN C . n 
E 1 19  THR 19  18  18  THR THR C . n 
E 1 20  LEU 20  19  19  LEU LEU C . n 
E 1 21  VAL 21  20  20  VAL VAL C . n 
E 1 22  LEU 22  21  21  LEU LEU C . n 
E 1 23  ASN 23  22  22  ASN ASN C . n 
E 1 24  PRO 24  23  23  PRO PRO C . n 
E 1 25  ARG 25  24  24  ARG ARG C . n 
E 1 26  GLY 26  25  25  GLY GLY C . n 
E 1 27  VAL 27  26  26  VAL VAL C . n 
E 1 28  ASN 28  27  27  ASN ASN C . n 
E 1 29  PRO 29  28  28  PRO PRO C . n 
E 1 30  THR 30  29  29  THR THR C . n 
E 1 31  ASN 31  30  30  ASN ASN C . n 
E 1 32  GLY 32  31  31  GLY GLY C . n 
E 1 33  VAL 33  32  32  VAL VAL C . n 
E 1 34  ALA 34  33  33  ALA ALA C . n 
E 1 35  SER 35  34  34  SER SER C . n 
E 1 36  LEU 36  35  35  LEU LEU C . n 
E 1 37  SER 37  36  36  SER SER C . n 
E 1 38  GLN 38  37  37  GLN GLN C . n 
E 1 39  ALA 39  38  38  ALA ALA C . n 
E 1 40  GLY 40  39  39  GLY GLY C . n 
E 1 41  ALA 41  40  40  ALA ALA C . n 
E 1 42  VAL 42  41  41  VAL VAL C . n 
E 1 43  PRO 43  42  42  PRO PRO C . n 
E 1 44  ALA 44  43  43  ALA ALA C . n 
E 1 45  LEU 45  44  44  LEU LEU C . n 
E 1 46  GLU 46  45  45  GLU GLU C . n 
E 1 47  LYS 47  46  46  LYS LYS C . n 
E 1 48  ARG 48  47  47  ARG ARG C . n 
E 1 49  VAL 49  48  48  VAL VAL C . n 
E 1 50  THR 50  49  49  THR THR C . n 
E 1 51  VAL 51  50  50  VAL VAL C . n 
E 1 52  SER 52  51  51  SER SER C . n 
E 1 53  VAL 53  52  52  VAL VAL C . n 
E 1 54  SER 54  53  53  SER SER C . n 
E 1 55  GLN 55  54  54  GLN GLN C . n 
E 1 56  PRO 56  55  55  PRO PRO C . n 
E 1 57  SER 57  56  56  SER SER C . n 
E 1 58  ARG 58  57  57  ARG ARG C . n 
E 1 59  ASN 59  58  58  ASN ASN C . n 
E 1 60  ARG 60  59  59  ARG ARG C . n 
E 1 61  LYS 61  60  60  LYS LYS C . n 
E 1 62  ASN 62  61  61  ASN ASN C . n 
E 1 63  TYR 63  62  62  TYR TYR C . n 
E 1 64  LYS 64  63  63  LYS LYS C . n 
E 1 65  VAL 65  64  64  VAL VAL C . n 
E 1 66  GLN 66  65  65  GLN GLN C . n 
E 1 67  VAL 67  66  66  VAL VAL C . n 
E 1 68  LYS 68  67  67  LYS LYS C . n 
E 1 69  ILE 69  68  68  ILE ILE C . n 
E 1 70  GLN 70  69  69  GLN GLN C . n 
E 1 71  ASN 71  70  70  ASN ASN C . n 
E 1 72  PRO 72  71  71  PRO PRO C . n 
E 1 73  THR 73  72  72  THR THR C . n 
E 1 74  ALA 74  73  73  ALA ALA C . n 
E 1 75  CYS 75  74  74  CYS CYS C . n 
E 1 76  THR 76  75  75  THR THR C . n 
E 1 77  ALA 77  76  76  ALA ALA C . n 
E 1 78  ASN 78  77  77  ASN ASN C . n 
E 1 79  GLY 79  78  78  GLY GLY C . n 
E 1 80  SER 80  79  79  SER SER C . n 
E 1 81  CYS 81  80  80  CYS CYS C . n 
E 1 82  ASP 82  81  81  ASP ASP C . n 
E 1 83  PRO 83  82  82  PRO PRO C . n 
E 1 84  SER 84  83  83  SER SER C . n 
E 1 85  VAL 85  84  84  VAL VAL C . n 
E 1 86  THR 86  85  85  THR THR C . n 
E 1 87  ARG 87  86  86  ARG ARG C . n 
E 1 88  GLN 88  87  87  GLN GLN C . n 
E 1 89  ALA 89  88  88  ALA ALA C . n 
E 1 90  TYR 90  89  89  TYR TYR C . n 
E 1 91  ALA 91  90  90  ALA ALA C . n 
E 1 92  ASP 92  91  91  ASP ASP C . n 
E 1 93  VAL 93  92  92  VAL VAL C . n 
E 1 94  THR 94  93  93  THR THR C . n 
E 1 95  PHE 95  94  94  PHE PHE C . n 
E 1 96  SER 96  95  95  SER SER C . n 
E 1 97  PHE 97  96  96  PHE PHE C . n 
E 1 98  THR 98  97  97  THR THR C . n 
E 1 99  GLN 99  98  98  GLN GLN C . n 
E 1 100 TYR 100 99  99  TYR TYR C . n 
E 1 101 SER 101 100 100 SER SER C . n 
E 1 102 THR 102 101 101 THR THR C . n 
E 1 103 ASP 103 102 102 ASP ASP C . n 
E 1 104 GLU 104 103 103 GLU GLU C . n 
E 1 105 GLU 105 104 104 GLU GLU C . n 
E 1 106 ARG 106 105 105 ARG ARG C . n 
E 1 107 ALA 107 106 106 ALA ALA C . n 
E 1 108 PHE 108 107 107 PHE PHE C . n 
E 1 109 VAL 109 108 108 VAL VAL C . n 
E 1 110 ARG 110 109 109 ARG ARG C . n 
E 1 111 THR 111 110 110 THR THR C . n 
E 1 112 GLU 112 111 111 GLU GLU C . n 
E 1 113 LEU 113 112 112 LEU LEU C . n 
E 1 114 ALA 114 113 113 ALA ALA C . n 
E 1 115 ALA 115 114 114 ALA ALA C . n 
E 1 116 LEU 116 115 115 LEU LEU C . n 
E 1 117 LEU 117 116 116 LEU LEU C . n 
E 1 118 ALA 118 117 117 ALA ALA C . n 
E 1 119 SER 119 118 118 SER SER C . n 
E 1 120 PRO 120 119 119 PRO PRO C . n 
E 1 121 LEU 121 120 120 LEU LEU C . n 
E 1 122 LEU 122 121 121 LEU LEU C . n 
E 1 123 ILE 123 122 122 ILE ILE C . n 
E 1 124 ASP 124 123 123 ASP ASP C . n 
E 1 125 ALA 125 124 124 ALA ALA C . n 
E 1 126 ILE 126 125 125 ILE ILE C . n 
E 1 127 ASP 127 126 126 ASP ASP C . n 
E 1 128 GLN 128 127 127 GLN GLN C . n 
E 1 129 LEU 129 128 128 LEU LEU C . n 
E 1 130 ASN 130 129 129 ASN ASN C . n 
E 1 131 PRO 131 130 130 PRO PRO C . n 
E 1 132 ALA 132 131 131 ALA ALA C . n 
E 1 133 TYR 133 132 132 TYR TYR C . n 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8W5R 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8W5R 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8W5R 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 8W5R 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.004 ? 4764 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.553 ? 6482 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 4.421 ? 660  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.047 ? 748  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.004 ? 840  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8W5R 
_struct.title                        'Cryo-EM structure of Qb-Ab53' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8W5R 
_struct_keywords.text            'Qb, Antibody, cryo-EM, IMMUNE SYSTEM' 
_struct_keywords.pdbx_keywords   'IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 3 ? 
E N N 1 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP A1_BPQBE Q8LTE1 ? 1 
;MAKLETVTLGNIGKDGKQTLVLNPRGVNPTNGVASLSQAGAVPALEKRVTVSVSQPSRNRKNYKVQVKIQNPTACTANGS
CDPSVTRQAYADVTFSFTQYSTDEERAFVRTELAALLASPLLIDAIDQLNPAY
;
1 
2 PDB 8W5R     8W5R   ? 2 ? 1 
3 PDB 8W5R     8W5R   ? 3 ? 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8W5R A 1 ? 133 ? Q8LTE1 1 ? 133 ? 0 132 
2 1 8W5R B 1 ? 133 ? Q8LTE1 1 ? 133 ? 0 132 
3 2 8W5R H 1 ? 125 ? 8W5R   1 ? 125 ? 1 125 
4 3 8W5R L 1 ? 110 ? 8W5R   1 ? 110 ? 1 110 
5 1 8W5R C 1 ? 133 ? Q8LTE1 1 ? 133 ? 0 132 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 'complete icosahedral assembly'                ? 300-meric  300 
2 'icosahedral asymmetric unit'                  ? pentameric 5   
3 'icosahedral pentamer'                         ? 25-meric   25  
4 'icosahedral 23 hexamer'                       ? 30-meric   30  
5 'icosahedral asymmetric unit, std point frame' ? pentameric 5   
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 '(1-60)'           A,B,C,D,E 
2 1                  A,B,C,D,E 
3 '(1-5)'            A,B,C,D,E 
4 '(1,2,6,10,23,24)' A,B,C,D,E 
5 P                  A,B,C,D,E 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
P  'transform to point frame' ?     ?     0.30901699  0.80901699  -0.50000000 -168.10524 -0.80901699 0.50000000  0.30901699  
0.00000    0.50000000  0.30901699  0.80901699  -440.10524 
1  'identity operation'       1_555 x,y,z 1.00000000  0.00000000  0.00000000  0.00000    0.00000000  1.00000000  0.00000000  
0.00000    0.00000000  0.00000000  1.00000000  0.00000    
2  'point symmetry operation' ?     ?     0.30901700  -0.80901699 0.50000000  271.99999  0.80901699  0.50000000  0.30901700  
-168.10524 -0.50000000 0.30901700  0.80901699  103.89475  
3  'point symmetry operation' ?     ?     -0.80901699 -0.50000000 0.30901700  543.99999  0.50000000  -0.30901700 0.80901700  
0.00000    -0.30901699 0.80901700  0.50000000  0.00000    
4  'point symmetry operation' ?     ?     -0.80901700 0.50000000  -0.30901700 440.10524  -0.50000000 -0.30901699 0.80901700  
271.99999  0.30901700  0.80901699  0.50000000  -168.10524 
5  'point symmetry operation' ?     ?     0.30901699  0.80901700  -0.50000000 103.89476  -0.80901699 0.50000000  0.30901699  
272.00000  0.50000000  0.30901699  0.80901700  -168.10524 
6  'point symmetry operation' ?     ?     -0.50000000 0.30901699  0.80901699  103.89475  0.30901700  -0.80901699 0.50000001  
271.99999  0.80901700  0.49999999  0.30901699  -168.10524 
7  'point symmetry operation' ?     ?     -0.30901700 0.80901699  0.50000000  0.00000    -0.80901699 -0.50000000 0.30901700  
543.99999  0.50000000  -0.30901700 0.80901699  0.00000    
8  'point symmetry operation' ?     ?     0.30901699  0.80901699  0.50000000  -168.10524 -0.80901700 0.50000000  -0.30901699 
440.10524  -0.50000000 -0.30901700 0.80901699  272.00000  
9  'point symmetry operation' ?     ?     0.50000000  0.30901699  0.80901699  -168.10524 0.30901699  0.80901700  -0.50000000 
103.89476  -0.80901700 0.50000000  0.30901699  272.00000  
10 'point symmetry operation' ?     ?     0.00000000  0.00000000  1.00000000  0.00000    1.00000000  0.00000000  0.00000000  
0.00000    0.00000000  1.00000000  0.00000000  0.00000    
11 'point symmetry operation' ?     ?     0.30901699  -0.80901700 -0.49999999 544.00000  -0.80901699 -0.50000000 0.30901699  
543.99999  -0.50000001 0.30901700  -0.80901699 544.00000  
12 'point symmetry operation' ?     ?     -0.30901700 -0.80901699 -0.50000000 712.10524  -0.80901699 0.50000000  -0.30901700 
440.10524  0.50000000  0.30901700  -0.80901699 272.00000  
13 'point symmetry operation' ?     ?     -0.50000000 -0.30901699 -0.80901700 712.10524  0.30901699  0.80901699  -0.50000000 
103.89476  0.80901700  -0.50000000 -0.30901699 272.00000  
14 'point symmetry operation' ?     ?     0.00000000  0.00000000  -1.00000000 544.00000  1.00000000  0.00000000  0.00000000  
0.00000    0.00000000  -1.00000000 0.00000000  543.99999  
15 'point symmetry operation' ?     ?     0.50000000  -0.30901700 -0.80901699 440.10524  0.30901700  -0.80901700 0.50000000  
272.00000  -0.80901700 -0.50000000 -0.30901699 712.10524  
16 'point symmetry operation' ?     ?     -0.80901699 0.50000001  -0.30901700 440.10524  0.49999999  0.30901699  -0.80901700 
272.00000  -0.30901699 -0.80901699 -0.50000000 712.10524  
17 'point symmetry operation' ?     ?     0.30901700  0.80901699  -0.50000000 103.89476  0.80901699  -0.50000000 -0.30901700 
272.00000  -0.50000000 -0.30901700 -0.80901699 712.10524  
18 'point symmetry operation' ?     ?     1.00000000  0.00000000  0.00000000  0.00000    0.00000000  -1.00000000 0.00000000  
543.99999  0.00000000  0.00000000  -1.00000000 544.00000  
19 'point symmetry operation' ?     ?     0.30901699  -0.80901700 0.50000000  272.00000  -0.80901699 -0.50000000 -0.30901700 
712.10524  0.50000000  -0.30901699 -0.80901699 440.10524  
20 'point symmetry operation' ?     ?     -0.80901699 -0.50000000 0.30901699  543.99999  -0.50000000 0.30901699  -0.80901700 
544.00000  0.30901700  -0.80901699 -0.50000000 544.00000  
21 'point symmetry operation' ?     ?     -0.49999999 -0.30901699 0.80901700  271.99999  0.30901699  0.80901699  0.50000000  
-168.10524 -0.80901699 0.50000001  -0.30901700 440.10524  
22 'point symmetry operation' ?     ?     -0.80901699 0.50000000  0.30901700  272.00000  0.50000000  0.30901700  0.80901699  
-168.10525 0.30901700  0.80901699  -0.50000000 103.89476  
23 'point symmetry operation' ?     ?     0.00000000  1.00000000  0.00000000  0.00000    0.00000000  0.00000000  1.00000000  
0.00000    1.00000000  0.00000000  0.00000000  0.00000    
24 'point symmetry operation' ?     ?     0.80901699  0.50000000  0.30901700  -168.10524 -0.50000000 0.30901699  0.80901699  
103.89475  0.30901699  -0.80901700 0.50000000  272.00000  
25 'point symmetry operation' ?     ?     0.50000000  -0.30901699 0.80901700  0.00000    -0.30901700 0.80901699  0.50000000  
0.00000    -0.80901699 -0.50000000 0.30901699  544.00000  
26 'point symmetry operation' ?     ?     0.80901699  0.50000000  -0.30901699 0.00000    0.50000001  -0.30901700 0.80901699  
0.00000    0.30901699  -0.80901700 -0.49999999 544.00000  
27 'point symmetry operation' ?     ?     0.80901699  -0.50000000 0.30901700  103.89475  -0.50000000 -0.30901700 0.80901699  
272.00000  -0.30901700 -0.80901699 -0.50000000 712.10524  
28 'point symmetry operation' ?     ?     -0.30901699 -0.80901699 0.50000000  440.10524  -0.80901700 0.50000000  0.30901699  
272.00000  -0.50000000 -0.30901699 -0.80901700 712.10524  
29 'point symmetry operation' ?     ?     -1.00000000 0.00000000  0.00000000  543.99999  0.00000000  1.00000000  0.00000000  
0.00000    0.00000000  0.00000000  -1.00000000 544.00000  
30 'point symmetry operation' ?     ?     -0.30901700 0.80901700  -0.50000000 272.00000  0.80901700  0.50000000  0.30901699  
-168.10524 0.50000000  -0.30901700 -0.80901699 440.10524  
31 'point symmetry operation' ?     ?     -0.30901700 0.80901699  -0.50000001 272.00000  -0.80901700 -0.49999999 -0.30901699 
712.10524  -0.50000000 0.30901699  0.80901699  103.89475  
32 'point symmetry operation' ?     ?     0.80901699  0.50000000  -0.30901700 0.00000    -0.50000000 0.30901700  -0.80901699 
544.00000  -0.30901700 0.80901699  0.50000000  0.00000    
33 'point symmetry operation' ?     ?     0.80901700  -0.50000000 0.30901699  103.89475  0.50000000  0.30901700  -0.80901699 
272.00000  0.30901699  0.80901699  0.50000000  -168.10524 
34 'point symmetry operation' ?     ?     -0.30901699 -0.80901700 0.50000000  440.10524  0.80901700  -0.50000000 -0.30901699 
272.00000  0.50000000  0.30901699  0.80901699  -168.10524 
35 'point symmetry operation' ?     ?     -1.00000000 0.00000000  0.00000000  544.00000  0.00000000  -1.00000000 0.00000000  
543.99999  0.00000000  0.00000000  1.00000000  0.00000    
36 'point symmetry operation' ?     ?     0.00000000  -1.00000000 0.00000000  544.00000  0.00000000  0.00000000  -1.00000000 
544.00000  1.00000000  0.00000000  0.00000000  0.00000    
37 'point symmetry operation' ?     ?     -0.80901699 -0.50000000 -0.30901700 712.10524  0.50000000  -0.30901700 -0.80901699 
440.10524  0.30901700  -0.80901699 0.50000000  272.00000  
38 'point symmetry operation' ?     ?     -0.50000000 0.30901700  -0.80901700 544.00000  0.30901699  -0.80901700 -0.50000000 
544.00000  -0.80901699 -0.50000000 0.30901700  543.99999  
39 'point symmetry operation' ?     ?     0.50000000  0.30901699  -0.80901700 272.00000  -0.30901700 -0.80901699 -0.50000000 
712.10524  -0.80901700 0.50000000  -0.30901700 440.10524  
40 'point symmetry operation' ?     ?     0.80901699  -0.50000000 -0.30901699 272.00000  -0.50000000 -0.30901699 -0.80901700 
712.10524  0.30901699  0.80901700  -0.50000000 103.89476  
41 'point symmetry operation' ?     ?     -0.50000001 0.30901700  -0.80901699 544.00000  -0.30901699 0.80901700  0.49999999  
0.00000    0.80901699  0.50000000  -0.30901699 0.00000    
42 'point symmetry operation' ?     ?     0.50000000  0.30901700  -0.80901699 272.00000  0.30901700  0.80901699  0.50000000  
-168.10524 0.80901699  -0.50000000 0.30901700  103.89475  
43 'point symmetry operation' ?     ?     0.80901700  -0.50000000 -0.30901699 272.00000  0.50000000  0.30901699  0.80901700  
-168.10524 -0.30901699 -0.80901699 0.50000000  440.10524  
44 'point symmetry operation' ?     ?     0.00000000  -1.00000000 0.00000000  543.99999  0.00000000  0.00000000  1.00000000  
0.00000    -1.00000000 0.00000000  0.00000000  544.00000  
45 'point symmetry operation' ?     ?     -0.80901700 -0.50000000 -0.30901699 712.10524  -0.50000000 0.30901700  0.80901699  
103.89475  -0.30901700 0.80901700  -0.50000000 272.00000  
46 'point symmetry operation' ?     ?     -0.30901699 -0.80901699 -0.50000000 712.10524  0.80901699  -0.50000001 0.30901700  
103.89475  -0.49999999 -0.30901699 0.80901700  271.99999  
47 'point symmetry operation' ?     ?     -0.50000000 -0.30901700 -0.80901699 712.10524  -0.30901700 -0.80901699 0.50000000  
440.10524  -0.80901699 0.50000000  0.30901700  272.00000  
48 'point symmetry operation' ?     ?     0.00000000  0.00000000  -1.00000000 544.00000  -1.00000000 0.00000000  0.00000000  
543.99999  0.00000000  1.00000000  0.00000000  0.00000    
49 'point symmetry operation' ?     ?     0.50000000  -0.30901699 -0.80901699 440.10524  -0.30901699 0.80901700  -0.50000000 
272.00000  0.80901699  0.50000000  0.30901700  -168.10524 
50 'point symmetry operation' ?     ?     0.30901700  -0.80901699 -0.50000000 543.99999  0.80901699  0.50000000  -0.30901699 
0.00000    0.50000000  -0.30901699 0.80901700  0.00000    
51 'point symmetry operation' ?     ?     0.00000000  0.00000000  1.00000000  0.00000    -1.00000000 0.00000000  0.00000000  
544.00000  0.00000000  -1.00000000 0.00000000  544.00000  
52 'point symmetry operation' ?     ?     -0.50000000 0.30901700  0.80901699  103.89475  -0.30901700 0.80901699  -0.50000000 
272.00000  -0.80901699 -0.50000000 -0.30901700 712.10524  
53 'point symmetry operation' ?     ?     -0.30901699 0.80901700  0.50000000  0.00000    0.80901699  0.50000000  -0.30901700 
0.00000    -0.50000000 0.30901700  -0.80901700 544.00000  
54 'point symmetry operation' ?     ?     0.30901700  0.80901699  0.50000000  -168.10524 0.80901700  -0.50000000 0.30901700  
103.89475  0.50000000  0.30901699  -0.80901700 272.00000  
55 'point symmetry operation' ?     ?     0.50000000  0.30901699  0.80901700  -168.10524 -0.30901699 -0.80901700 0.50000000  
440.10524  0.80901699  -0.50000000 -0.30901699 272.00000  
56 'point symmetry operation' ?     ?     0.80901700  0.49999999  0.30901699  -168.10524 0.50000000  -0.30901699 -0.80901699 
440.10524  -0.30901700 0.80901699  -0.50000001 272.00000  
57 'point symmetry operation' ?     ?     0.50000000  -0.30901700 0.80901699  0.00000    0.30901700  -0.80901699 -0.50000000 
543.99999  0.80901699  0.50000000  -0.30901700 0.00000    
58 'point symmetry operation' ?     ?     -0.50000000 -0.30901700 0.80901699  272.00000  -0.30901699 -0.80901699 -0.50000000 
712.10524  0.80901700  -0.50000000 0.30901699  103.89475  
59 'point symmetry operation' ?     ?     -0.80901700 0.50000000  0.30901699  272.00000  -0.50000000 -0.30901699 -0.80901699 
712.10524  -0.30901699 -0.80901700 0.50000000  440.10524  
60 'point symmetry operation' ?     ?     0.00000000  1.00000000  0.00000000  0.00000    0.00000000  0.00000000  -1.00000000 
544.00000  -1.00000000 0.00000000  0.00000000  544.00000  
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 AA1 THR A 102 ? LEU A 117 ? THR A 101 LEU A 116 1 ? 16 
HELX_P HELX_P2 AA2 SER A 119 ? ASP A 127 ? SER A 118 ASP A 126 1 ? 9  
HELX_P HELX_P3 AA3 VAL B 42  ? GLU B 46  ? VAL B 41  GLU B 45  5 ? 5  
HELX_P HELX_P4 AA4 THR B 102 ? LEU B 117 ? THR B 101 LEU B 116 1 ? 16 
HELX_P HELX_P5 AA5 SER B 119 ? GLN B 128 ? SER B 118 GLN B 127 1 ? 10 
HELX_P HELX_P6 AA6 VAL E 42  ? GLU E 46  ? VAL C 41  GLU C 45  5 ? 5  
HELX_P HELX_P7 AA7 THR E 102 ? LEU E 117 ? THR C 101 LEU C 116 1 ? 16 
HELX_P HELX_P8 AA8 SER E 119 ? GLN E 128 ? SER C 118 GLN C 127 1 ? 10 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 12 ? 
AA2 ? 4  ? 
AA3 ? 5  ? 
AA4 ? 5  ? 
AA5 ? 4  ? 
AA6 ? 4  ? 
AA7 ? 6  ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1  2  ? anti-parallel 
AA1 2  3  ? anti-parallel 
AA1 3  4  ? anti-parallel 
AA1 4  5  ? anti-parallel 
AA1 5  6  ? anti-parallel 
AA1 6  7  ? anti-parallel 
AA1 7  8  ? anti-parallel 
AA1 8  9  ? anti-parallel 
AA1 9  10 ? anti-parallel 
AA1 10 11 ? anti-parallel 
AA1 11 12 ? anti-parallel 
AA2 1  2  ? anti-parallel 
AA2 2  3  ? anti-parallel 
AA2 3  4  ? anti-parallel 
AA3 1  2  ? anti-parallel 
AA3 2  3  ? anti-parallel 
AA3 3  4  ? anti-parallel 
AA3 4  5  ? anti-parallel 
AA4 1  2  ? anti-parallel 
AA4 2  3  ? anti-parallel 
AA4 3  4  ? anti-parallel 
AA4 4  5  ? anti-parallel 
AA5 1  2  ? anti-parallel 
AA5 2  3  ? anti-parallel 
AA5 3  4  ? anti-parallel 
AA6 1  2  ? anti-parallel 
AA6 2  3  ? anti-parallel 
AA6 3  4  ? anti-parallel 
AA7 1  2  ? anti-parallel 
AA7 2  3  ? anti-parallel 
AA7 3  4  ? anti-parallel 
AA7 4  5  ? anti-parallel 
AA7 5  6  ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1  VAL A 7   ? ILE A 12  ? VAL A 6   ILE A 11  
AA1 2  GLN A 18  ? VAL A 27  ? GLN A 17  VAL A 26  
AA1 3  ALA A 34  ? GLN A 38  ? ALA A 33  GLN A 37  
AA1 4  ARG A 48  ? SER A 54  ? ARG A 47  SER A 53  
AA1 5  LYS A 64  ? CYS A 75  ? LYS A 63  CYS A 74  
AA1 6  SER A 84  ? SER A 96  ? SER A 83  SER A 95  
AA1 7  SER B 84  ? PHE B 97  ? SER B 83  PHE B 96  
AA1 8  TYR B 63  ? CYS B 75  ? TYR B 62  CYS B 74  
AA1 9  ARG B 48  ? SER B 54  ? ARG B 47  SER B 53  
AA1 10 ALA B 34  ? SER B 37  ? ALA B 33  SER B 36  
AA1 11 GLN B 18  ? VAL B 27  ? GLN B 17  VAL B 26  
AA1 12 VAL B 7   ? ILE B 12  ? VAL B 6   ILE B 11  
AA2 1  GLN C 6   ? GLN C 8   ? GLN H 6   GLN H 8   
AA2 2  CYS C 25  ? SER C 28  ? CYS H 25  SER H 28  
AA2 3  THR C 81  ? LEU C 86  ? THR H 81  LEU H 86  
AA2 4  ALA C 71  ? ASP C 76  ? ALA H 71  ASP H 76  
AA3 1  ASN C 62  ? TYR C 63  ? ASN H 62  TYR H 63  
AA3 2  GLY C 47  ? ILE C 54  ? GLY H 47  ILE H 54  
AA3 3  TRP C 36  ? ARG C 43  ? TRP H 36  ARG H 43  
AA3 4  ARG C 101 ? TYR C 105 ? ARG H 101 TYR H 105 
AA3 5  TYR C 108 ? ASP C 112 ? TYR H 108 ASP H 112 
AA4 1  ASN C 62  ? TYR C 63  ? ASN H 62  TYR H 63  
AA4 2  GLY C 47  ? ILE C 54  ? GLY H 47  ILE H 54  
AA4 3  TRP C 36  ? ARG C 43  ? TRP H 36  ARG H 43  
AA4 4  VAL C 96  ? TYR C 98  ? VAL H 96  TYR H 98  
AA4 5  THR C 118 ? SER C 119 ? THR H 118 SER H 119 
AA5 1  MET D 7   ? GLN D 9   ? MET L 7   GLN L 9   
AA5 2  VAL D 22  ? ALA D 28  ? VAL L 22  ALA L 28  
AA5 3  GLN D 73  ? ILE D 78  ? GLN L 73  ILE L 78  
AA5 4  PHE D 65  ? SER D 68  ? PHE L 65  SER L 68  
AA6 1  GLN D 48  ? LEU D 50  ? GLN L 48  LEU L 50  
AA6 2  LEU D 36  ? GLN D 41  ? LEU L 36  GLN L 41  
AA6 3  ASN D 88  ? HIS D 93  ? ASN L 88  HIS L 93  
AA6 4  THR D 105 ? LYS D 106 ? THR L 105 LYS L 106 
AA7 1  VAL E 7   ? ILE E 12  ? VAL C 6   ILE C 11  
AA7 2  GLN E 18  ? PRO E 24  ? GLN C 17  PRO C 23  
AA7 3  VAL E 33  ? GLN E 38  ? VAL C 32  GLN C 37  
AA7 4  ARG E 48  ? VAL E 53  ? ARG C 47  VAL C 52  
AA7 5  ASN E 62  ? CYS E 75  ? ASN C 61  CYS C 74  
AA7 6  SER E 84  ? THR E 98  ? SER C 83  THR C 97  
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1  2  N LEU A 9   ? N LEU A 8   O LEU A 20  ? O LEU A 19  
AA1 2  3  N ASN A 23  ? N ASN A 22  O SER A 37  ? O SER A 36  
AA1 3  4  N LEU A 36  ? N LEU A 35  O VAL A 49  ? O VAL A 48  
AA1 4  5  N THR A 50  ? N THR A 49  O LYS A 68  ? O LYS A 67  
AA1 5  6  N VAL A 67  ? N VAL A 66  O VAL A 93  ? O VAL A 92  
AA1 6  7  N THR A 94  ? N THR A 93  O ASP B 92  ? O ASP B 91  
AA1 7  8  O THR B 86  ? O THR B 85  N THR B 73  ? N THR B 72  
AA1 8  9  O LYS B 68  ? O LYS B 67  N THR B 50  ? N THR B 49  
AA1 9  10 O VAL B 49  ? O VAL B 48  N LEU B 36  ? N LEU B 35  
AA1 10 11 O SER B 37  ? O SER B 36  N ASN B 23  ? N ASN B 22  
AA1 11 12 O LEU B 20  ? O LEU B 19  N LEU B 9   ? N LEU B 8   
AA2 1  2  N GLN C 8   ? N GLN H 8   O LYS C 26  ? O LYS H 26  
AA2 2  3  N CYS C 25  ? N CYS H 25  O ALA C 82  ? O ALA H 82  
AA2 3  4  O TYR C 83  ? O TYR H 83  N THR C 74  ? N THR H 74  
AA3 1  2  O ASN C 62  ? O ASN H 62  N MET C 53  ? N MET H 53  
AA3 2  3  O ILE C 51  ? O ILE H 51  N TRP C 39  ? N TRP H 39  
AA3 3  4  N TRP C 36  ? N TRP H 36  O GLY C 102 ? O GLY H 102 
AA3 4  5  N VAL C 103 ? N VAL H 103 O ALA C 110 ? O ALA H 110 
AA4 1  2  O ASN C 62  ? O ASN H 62  N MET C 53  ? N MET H 53  
AA4 2  3  O ILE C 51  ? O ILE H 51  N TRP C 39  ? N TRP H 39  
AA4 3  4  N VAL C 40  ? N VAL H 40  O TYR C 98  ? O TYR H 98  
AA4 4  5  N TYR C 97  ? N TYR H 97  O THR C 118 ? O THR H 118 
AA5 1  2  N THR D 8   ? N THR L 8   O ARG D 27  ? O ARG L 27  
AA5 2  3  N CYS D 26  ? N CYS L 26  O TYR D 74  ? O TYR L 74  
AA5 3  4  O LYS D 77  ? O LYS L 77  N SER D 66  ? N SER L 66  
AA6 1  2  O GLN D 48  ? O GLN L 48  N GLN D 40  ? N GLN L 40  
AA6 2  3  N TYR D 39  ? N TYR L 39  O TYR D 90  ? O TYR L 90  
AA6 3  4  N TYR D 89  ? N TYR L 89  O THR D 105 ? O THR L 105 
AA7 1  2  N LEU E 9   ? N LEU C 8   O LEU E 20  ? O LEU C 19  
AA7 2  3  N ASN E 23  ? N ASN C 22  O SER E 37  ? O SER C 36  
AA7 3  4  N LEU E 36  ? N LEU C 35  O VAL E 49  ? O VAL C 48  
AA7 4  5  N SER E 52  ? N SER C 51  O GLN E 66  ? O GLN C 65  
AA7 5  6  N VAL E 67  ? N VAL C 66  O VAL E 93  ? O VAL C 92  
# 
_pdbx_entry_details.entry_id                   8W5R 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ALA A 40 ? ? 59.62   -177.47 
2  1 LEU A 44 ? ? -140.52 30.10   
3  1 GLU H 65 ? ? 72.38   -8.48   
4  1 SER H 79 ? ? 69.37   -1.32   
5  1 SER H 91 ? ? 67.90   -3.47   
6  1 ASP H 93 ? ? -93.23  57.37   
7  1 ALA L 12 ? ? 67.17   -6.14   
8  1 VAL L 51 ? ? 61.84   -67.72  
9  1 TYR L 52 ? ? 59.57   -0.59   
10 1 HIS L 53 ? ? -142.03 18.64   
11 1 ALA L 54 ? ? 67.39   -7.07   
12 1 SER L 63 ? ? 70.74   -2.04   
13 1 VAL C 41 ? ? 57.79   74.79   
14 1 PRO C 42 ? ? -53.07  -9.99   
# 
_pdbx_point_symmetry.entry_id             8W5R 
_pdbx_point_symmetry.Schoenflies_symbol   I 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8W5R 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8W5R 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.1 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               19726 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Complex of Qb-Ab53' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1,2,3 
# 
_em_imaging.entry_id                        8W5R 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1200 
_em_imaging.nominal_defocus_max             1600 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8W5R 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8W5R 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 0   ? A MET 1   
2  1 Y 1 A ASN 77  ? A ASN 78  
3  1 Y 1 A GLY 78  ? A GLY 79  
4  1 Y 1 B MET 0   ? B MET 1   
5  1 Y 1 B ASN 77  ? B ASN 78  
6  1 Y 1 B GLY 78  ? B GLY 79  
7  1 Y 1 H VAL 1   ? C VAL 1   
8  1 Y 1 H HIS 2   ? C HIS 2   
9  1 Y 1 H SER 3   ? C SER 3   
10 1 Y 1 H GLN 4   ? C GLN 4   
11 1 Y 1 H VAL 122 ? C VAL 122 
12 1 Y 1 H SER 123 ? C SER 123 
13 1 Y 1 H SER 124 ? C SER 124 
14 1 Y 1 H ALA 125 ? C ALA 125 
15 1 Y 1 L VAL 1   ? D VAL 1   
16 1 Y 1 L HIS 2   ? D HIS 2   
17 1 Y 1 L SER 3   ? D SER 3   
18 1 Y 1 L ASP 4   ? D ASP 4   
19 1 Y 1 L GLU 108 ? D GLU 108 
20 1 Y 1 L ILE 109 ? D ILE 109 
21 1 Y 1 L LYS 110 ? D LYS 110 
22 1 Y 1 C MET 0   ? E MET 1   
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-08-27 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8W5R 
_em_admin.last_update        2025-02-26 
_em_admin.map_release_date   2025-02-26 
_em_admin.title              'Cryo-EM structure of Qb-Ab53' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          10088 
_em_entity_assembly_naturalsource.organism             Mus 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         60 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K2 SUMMIT (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ?      ?            
'MODEL REFINEMENT'         ? 2  ? ? ? PHENIX 1.19.2_4158: 
'IMAGE ACQUISITION'        ? 3  ? ? 1 ?      ?            
MASKING                    ? 4  ? ? ? ?      ?            
'CTF CORRECTION'           ? 5  1 ? ? ?      ?            
'LAYERLINE INDEXING'       ? 6  ? ? ? ?      ?            
'DIFFRACTION INDEXING'     ? 7  ? ? ? ?      ?            
'MODEL FITTING'            ? 8  ? ? ? ?      ?            
OTHER                      ? 9  ? ? ? ?      ?            
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ?      ?            
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ?      ?            
CLASSIFICATION             ? 12 1 ? ? ?      ?            
RECONSTRUCTION             ? 13 1 ? ? ?      ?            
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Natural Science Foundation of China (NSFC)' China 81991495    1 
'National Natural Science Foundation of China (NSFC)' China 32241029    2 
'Chinese Academy of Sciences'                         China XDB29050600 3 
'Chinese Academy of Sciences'                         China XDB37010100 4 
# 
_atom_sites.entry_id                    8W5R 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . ALA A 1 2   ? 308.466 325.395 390.355 1.00 57.14  ? 1   ALA A N   1 
ATOM 2    C CA  . ALA A 1 2   ? 308.645 323.950 390.293 1.00 57.14  ? 1   ALA A CA  1 
ATOM 3    C C   . ALA A 1 2   ? 309.919 323.597 389.546 1.00 57.14  ? 1   ALA A C   1 
ATOM 4    O O   . ALA A 1 2   ? 310.010 323.777 388.333 1.00 57.14  ? 1   ALA A O   1 
ATOM 5    C CB  . ALA A 1 2   ? 307.444 323.296 389.632 1.00 57.14  ? 1   ALA A CB  1 
ATOM 6    N N   . LYS A 1 3   ? 310.903 323.092 390.280 1.00 57.81  ? 2   LYS A N   1 
ATOM 7    C CA  . LYS A 1 3   ? 312.180 322.681 389.718 1.00 57.81  ? 2   LYS A CA  1 
ATOM 8    C C   . LYS A 1 3   ? 312.303 321.170 389.826 1.00 57.81  ? 2   LYS A C   1 
ATOM 9    O O   . LYS A 1 3   ? 312.097 320.606 390.905 1.00 57.81  ? 2   LYS A O   1 
ATOM 10   C CB  . LYS A 1 3   ? 313.339 323.362 390.446 1.00 57.81  ? 2   LYS A CB  1 
ATOM 11   C CG  . LYS A 1 3   ? 314.706 322.833 390.068 1.00 57.81  ? 2   LYS A CG  1 
ATOM 12   C CD  . LYS A 1 3   ? 315.800 323.675 390.692 1.00 57.81  ? 2   LYS A CD  1 
ATOM 13   C CE  . LYS A 1 3   ? 315.661 323.712 392.202 1.00 57.81  ? 2   LYS A CE  1 
ATOM 14   N NZ  . LYS A 1 3   ? 316.986 323.724 392.875 1.00 57.81  ? 2   LYS A NZ  1 
ATOM 15   N N   . LEU A 1 4   ? 312.622 320.519 388.709 1.00 52.37  ? 3   LEU A N   1 
ATOM 16   C CA  . LEU A 1 4   ? 312.813 319.076 388.729 1.00 52.37  ? 3   LEU A CA  1 
ATOM 17   C C   . LEU A 1 4   ? 313.932 318.716 389.695 1.00 52.37  ? 3   LEU A C   1 
ATOM 18   O O   . LEU A 1 4   ? 315.002 319.329 389.686 1.00 52.37  ? 3   LEU A O   1 
ATOM 19   C CB  . LEU A 1 4   ? 313.125 318.553 387.332 1.00 52.37  ? 3   LEU A CB  1 
ATOM 20   C CG  . LEU A 1 4   ? 311.923 317.980 386.586 1.00 52.37  ? 3   LEU A CG  1 
ATOM 21   C CD1 . LEU A 1 4   ? 312.339 317.472 385.224 1.00 52.37  ? 3   LEU A CD1 1 
ATOM 22   C CD2 . LEU A 1 4   ? 311.297 316.871 387.399 1.00 52.37  ? 3   LEU A CD2 1 
ATOM 23   N N   . GLU A 1 5   ? 313.673 317.718 390.530 1.00 56.87  ? 4   GLU A N   1 
ATOM 24   C CA  . GLU A 1 5   ? 314.517 317.446 391.681 1.00 56.87  ? 4   GLU A CA  1 
ATOM 25   C C   . GLU A 1 5   ? 314.171 316.058 392.195 1.00 56.87  ? 4   GLU A C   1 
ATOM 26   O O   . GLU A 1 5   ? 313.083 315.538 391.936 1.00 56.87  ? 4   GLU A O   1 
ATOM 27   C CB  . GLU A 1 5   ? 314.305 318.513 392.760 1.00 56.87  ? 4   GLU A CB  1 
ATOM 28   C CG  . GLU A 1 5   ? 315.172 318.392 393.990 1.00 56.87  ? 4   GLU A CG  1 
ATOM 29   C CD  . GLU A 1 5   ? 314.803 319.414 395.044 1.00 56.87  ? 4   GLU A CD  1 
ATOM 30   O OE1 . GLU A 1 5   ? 313.889 320.225 394.789 1.00 56.87  ? 4   GLU A OE1 1 
ATOM 31   O OE2 . GLU A 1 5   ? 315.424 319.407 396.126 1.00 56.87  ? 4   GLU A OE2 1 
ATOM 32   N N   . THR A 1 6   ? 315.112 315.457 392.916 1.00 52.00  ? 5   THR A N   1 
ATOM 33   C CA  . THR A 1 6   ? 314.851 314.160 393.521 1.00 52.00  ? 5   THR A CA  1 
ATOM 34   C C   . THR A 1 6   ? 313.713 314.274 394.525 1.00 52.00  ? 5   THR A C   1 
ATOM 35   O O   . THR A 1 6   ? 313.719 315.153 395.392 1.00 52.00  ? 5   THR A O   1 
ATOM 36   C CB  . THR A 1 6   ? 316.106 313.629 394.208 1.00 52.00  ? 5   THR A CB  1 
ATOM 37   O OG1 . THR A 1 6   ? 316.298 314.321 395.446 1.00 52.00  ? 5   THR A OG1 1 
ATOM 38   C CG2 . THR A 1 6   ? 317.322 313.841 393.324 1.00 52.00  ? 5   THR A CG2 1 
ATOM 39   N N   . VAL A 1 7   ? 312.736 313.381 394.405 1.00 45.10  ? 6   VAL A N   1 
ATOM 40   C CA  . VAL A 1 7   ? 311.566 313.354 395.273 1.00 45.10  ? 6   VAL A CA  1 
ATOM 41   C C   . VAL A 1 7   ? 311.607 312.067 396.080 1.00 45.10  ? 6   VAL A C   1 
ATOM 42   O O   . VAL A 1 7   ? 311.696 310.974 395.509 1.00 45.10  ? 6   VAL A O   1 
ATOM 43   C CB  . VAL A 1 7   ? 310.262 313.454 394.465 1.00 45.10  ? 6   VAL A CB  1 
ATOM 44   C CG1 . VAL A 1 7   ? 309.078 313.082 395.330 1.00 45.10  ? 6   VAL A CG1 1 
ATOM 45   C CG2 . VAL A 1 7   ? 310.095 314.850 393.910 1.00 45.10  ? 6   VAL A CG2 1 
ATOM 46   N N   . THR A 1 8   ? 311.545 312.193 397.400 1.00 45.01  ? 7   THR A N   1 
ATOM 47   C CA  . THR A 1 8   ? 311.625 311.053 398.300 1.00 45.01  ? 7   THR A CA  1 
ATOM 48   C C   . THR A 1 8   ? 310.328 310.915 399.082 1.00 45.01  ? 7   THR A C   1 
ATOM 49   O O   . THR A 1 8   ? 309.811 311.899 399.620 1.00 45.01  ? 7   THR A O   1 
ATOM 50   C CB  . THR A 1 8   ? 312.823 311.182 399.245 1.00 45.01  ? 7   THR A CB  1 
ATOM 51   O OG1 . THR A 1 8   ? 312.813 310.106 400.190 1.00 45.01  ? 7   THR A OG1 1 
ATOM 52   C CG2 . THR A 1 8   ? 312.814 312.511 399.964 1.00 45.01  ? 7   THR A CG2 1 
ATOM 53   N N   . LEU A 1 9   ? 309.800 309.694 399.127 1.00 47.02  ? 8   LEU A N   1 
ATOM 54   C CA  . LEU A 1 9   ? 308.568 309.379 399.836 1.00 47.02  ? 8   LEU A CA  1 
ATOM 55   C C   . LEU A 1 9   ? 308.895 308.382 400.936 1.00 47.02  ? 8   LEU A C   1 
ATOM 56   O O   . LEU A 1 9   ? 309.421 307.301 400.656 1.00 47.02  ? 8   LEU A O   1 
ATOM 57   C CB  . LEU A 1 9   ? 307.522 308.803 398.882 1.00 47.02  ? 8   LEU A CB  1 
ATOM 58   C CG  . LEU A 1 9   ? 307.461 309.427 397.489 1.00 47.02  ? 8   LEU A CG  1 
ATOM 59   C CD1 . LEU A 1 9   ? 306.467 308.693 396.619 1.00 47.02  ? 8   LEU A CD1 1 
ATOM 60   C CD2 . LEU A 1 9   ? 307.112 310.895 397.572 1.00 47.02  ? 8   LEU A CD2 1 
ATOM 61   N N   . GLY A 1 10  ? 308.584 308.738 402.178 1.00 52.99  ? 9   GLY A N   1 
ATOM 62   C CA  . GLY A 1 10  ? 308.914 307.920 403.328 1.00 52.99  ? 9   GLY A CA  1 
ATOM 63   C C   . GLY A 1 10  ? 307.670 307.403 404.024 1.00 52.99  ? 9   GLY A C   1 
ATOM 64   O O   . GLY A 1 10  ? 306.609 308.027 403.967 1.00 52.99  ? 9   GLY A O   1 
ATOM 65   N N   . ASN A 1 11  ? 307.814 306.257 404.687 1.00 56.00  ? 10  ASN A N   1 
ATOM 66   C CA  . ASN A 1 11  ? 306.729 305.628 405.438 1.00 56.00  ? 10  ASN A CA  1 
ATOM 67   C C   . ASN A 1 11  ? 305.500 305.396 404.565 1.00 56.00  ? 10  ASN A C   1 
ATOM 68   O O   . ASN A 1 11  ? 304.381 305.787 404.902 1.00 56.00  ? 10  ASN A O   1 
ATOM 69   C CB  . ASN A 1 11  ? 306.374 306.445 406.679 1.00 56.00  ? 10  ASN A CB  1 
ATOM 70   C CG  . ASN A 1 11  ? 307.273 306.130 407.854 1.00 56.00  ? 10  ASN A CG  1 
ATOM 71   O OD1 . ASN A 1 11  ? 308.487 306.019 407.706 1.00 56.00  ? 10  ASN A OD1 1 
ATOM 72   N ND2 . ASN A 1 11  ? 306.681 305.989 409.033 1.00 56.00  ? 10  ASN A ND2 1 
ATOM 73   N N   . ILE A 1 12  ? 305.718 304.750 403.425 1.00 51.25  ? 11  ILE A N   1 
ATOM 74   C CA  . ILE A 1 12  ? 304.635 304.331 402.554 1.00 51.25  ? 11  ILE A CA  1 
ATOM 75   C C   . ILE A 1 12  ? 304.603 302.808 402.515 1.00 51.25  ? 11  ILE A C   1 
ATOM 76   O O   . ILE A 1 12  ? 305.441 302.129 403.106 1.00 51.25  ? 11  ILE A O   1 
ATOM 77   C CB  . ILE A 1 12  ? 304.755 304.928 401.141 1.00 51.25  ? 11  ILE A CB  1 
ATOM 78   C CG1 . ILE A 1 12  ? 306.043 304.469 400.467 1.00 51.25  ? 11  ILE A CG1 1 
ATOM 79   C CG2 . ILE A 1 12  ? 304.704 306.440 401.201 1.00 51.25  ? 11  ILE A CG2 1 
ATOM 80   C CD1 . ILE A 1 12  ? 306.026 304.641 398.975 1.00 51.25  ? 11  ILE A CD1 1 
ATOM 81   N N   . GLY A 1 13  ? 303.615 302.272 401.811 1.00 53.47  ? 12  GLY A N   1 
ATOM 82   C CA  . GLY A 1 13  ? 303.366 300.847 401.792 1.00 53.47  ? 12  GLY A CA  1 
ATOM 83   C C   . GLY A 1 13  ? 302.328 300.442 402.825 1.00 53.47  ? 12  GLY A C   1 
ATOM 84   O O   . GLY A 1 13  ? 301.898 301.226 403.673 1.00 53.47  ? 12  GLY A O   1 
ATOM 85   N N   . LYS A 1 14  ? 301.916 299.176 402.737 1.00 58.64  ? 13  LYS A N   1 
ATOM 86   C CA  . LYS A 1 14  ? 300.886 298.676 403.641 1.00 58.64  ? 13  LYS A CA  1 
ATOM 87   C C   . LYS A 1 14  ? 301.353 298.710 405.090 1.00 58.64  ? 13  LYS A C   1 
ATOM 88   O O   . LYS A 1 14  ? 300.603 299.120 405.982 1.00 58.64  ? 13  LYS A O   1 
ATOM 89   C CB  . LYS A 1 14  ? 300.481 297.258 403.245 1.00 58.64  ? 13  LYS A CB  1 
ATOM 90   C CG  . LYS A 1 14  ? 299.342 296.695 404.073 1.00 58.64  ? 13  LYS A CG  1 
ATOM 91   C CD  . LYS A 1 14  ? 299.015 295.269 403.675 1.00 58.64  ? 13  LYS A CD  1 
ATOM 92   C CE  . LYS A 1 14  ? 297.981 295.235 402.563 1.00 58.64  ? 13  LYS A CE  1 
ATOM 93   N NZ  . LYS A 1 14  ? 297.249 293.941 402.529 1.00 58.64  ? 13  LYS A NZ  1 
ATOM 94   N N   . ASP A 1 15  ? 302.592 298.287 405.343 1.00 64.93  ? 14  ASP A N   1 
ATOM 95   C CA  . ASP A 1 15  ? 303.104 298.283 406.709 1.00 64.93  ? 14  ASP A CA  1 
ATOM 96   C C   . ASP A 1 15  ? 303.413 299.695 407.190 1.00 64.93  ? 14  ASP A C   1 
ATOM 97   O O   . ASP A 1 15  ? 303.284 299.993 408.382 1.00 64.93  ? 14  ASP A O   1 
ATOM 98   C CB  . ASP A 1 15  ? 304.348 297.401 406.798 1.00 64.93  ? 14  ASP A CB  1 
ATOM 99   C CG  . ASP A 1 15  ? 305.328 297.665 405.676 1.00 64.93  ? 14  ASP A CG  1 
ATOM 100  O OD1 . ASP A 1 15  ? 304.877 297.842 404.526 1.00 64.93  ? 14  ASP A OD1 1 
ATOM 101  O OD2 . ASP A 1 15  ? 306.548 297.694 405.940 1.00 64.93  ? 14  ASP A OD2 1 
ATOM 102  N N   . GLY A 1 16  ? 303.819 300.574 406.282 1.00 60.70  ? 15  GLY A N   1 
ATOM 103  C CA  . GLY A 1 16  ? 304.195 301.922 406.642 1.00 60.70  ? 15  GLY A CA  1 
ATOM 104  C C   . GLY A 1 16  ? 305.671 302.144 406.878 1.00 60.70  ? 15  GLY A C   1 
ATOM 105  O O   . GLY A 1 16  ? 306.032 303.155 407.489 1.00 60.70  ? 15  GLY A O   1 
ATOM 106  N N   . LYS A 1 17  ? 306.535 301.236 406.423 1.00 62.42  ? 16  LYS A N   1 
ATOM 107  C CA  . LYS A 1 17  ? 307.966 301.356 406.647 1.00 62.42  ? 16  LYS A CA  1 
ATOM 108  C C   . LYS A 1 17  ? 308.778 301.583 405.382 1.00 62.42  ? 16  LYS A C   1 
ATOM 109  O O   . LYS A 1 17  ? 309.888 302.114 405.473 1.00 62.42  ? 16  LYS A O   1 
ATOM 110  C CB  . LYS A 1 17  ? 308.500 300.100 407.351 1.00 62.42  ? 16  LYS A CB  1 
ATOM 111  C CG  . LYS A 1 17  ? 307.724 299.709 408.596 1.00 62.42  ? 16  LYS A CG  1 
ATOM 112  C CD  . LYS A 1 17  ? 307.693 300.843 409.606 1.00 62.42  ? 16  LYS A CD  1 
ATOM 113  C CE  . LYS A 1 17  ? 306.702 300.562 410.722 1.00 62.42  ? 16  LYS A CE  1 
ATOM 114  N NZ  . LYS A 1 17  ? 306.565 301.724 411.641 1.00 62.42  ? 16  LYS A NZ  1 
ATOM 115  N N   . GLN A 1 18  ? 308.267 301.197 404.218 1.00 58.10  ? 17  GLN A N   1 
ATOM 116  C CA  . GLN A 1 18  ? 309.039 301.315 402.991 1.00 58.10  ? 17  GLN A CA  1 
ATOM 117  C C   . GLN A 1 18  ? 309.192 302.771 402.573 1.00 58.10  ? 17  GLN A C   1 
ATOM 118  O O   . GLN A 1 18  ? 308.331 303.613 402.835 1.00 58.10  ? 17  GLN A O   1 
ATOM 119  C CB  . GLN A 1 18  ? 308.383 300.521 401.865 1.00 58.10  ? 17  GLN A CB  1 
ATOM 120  C CG  . GLN A 1 18  ? 308.624 299.031 401.941 1.00 58.10  ? 17  GLN A CG  1 
ATOM 121  C CD  . GLN A 1 18  ? 307.427 298.229 401.486 1.00 58.10  ? 17  GLN A CD  1 
ATOM 122  O OE1 . GLN A 1 18  ? 306.560 297.882 402.286 1.00 58.10  ? 17  GLN A OE1 1 
ATOM 123  N NE2 . GLN A 1 18  ? 307.373 297.928 400.195 1.00 58.10  ? 17  GLN A NE2 1 
ATOM 124  N N   . THR A 1 19  ? 310.313 303.061 401.918 1.00 54.98  ? 18  THR A N   1 
ATOM 125  C CA  . THR A 1 19  ? 310.591 304.378 401.371 1.00 54.98  ? 18  THR A CA  1 
ATOM 126  C C   . THR A 1 19  ? 310.944 304.241 399.899 1.00 54.98  ? 18  THR A C   1 
ATOM 127  O O   . THR A 1 19  ? 311.464 303.212 399.462 1.00 54.98  ? 18  THR A O   1 
ATOM 128  C CB  . THR A 1 19  ? 311.741 305.077 402.104 1.00 54.98  ? 18  THR A CB  1 
ATOM 129  O OG1 . THR A 1 19  ? 312.952 304.340 401.905 1.00 54.98  ? 18  THR A OG1 1 
ATOM 130  C CG2 . THR A 1 19  ? 311.452 305.167 403.592 1.00 54.98  ? 18  THR A CG2 1 
ATOM 131  N N   . LEU A 1 20  ? 310.651 305.289 399.135 1.00 46.58  ? 19  LEU A N   1 
ATOM 132  C CA  . LEU A 1 20  ? 310.954 305.312 397.712 1.00 46.58  ? 19  LEU A CA  1 
ATOM 133  C C   . LEU A 1 20  ? 311.536 306.668 397.355 1.00 46.58  ? 19  LEU A C   1 
ATOM 134  O O   . LEU A 1 20  ? 310.984 307.702 397.740 1.00 46.58  ? 19  LEU A O   1 
ATOM 135  C CB  . LEU A 1 20  ? 309.701 305.032 396.878 1.00 46.58  ? 19  LEU A CB  1 
ATOM 136  C CG  . LEU A 1 20  ? 309.820 305.228 395.370 1.00 46.58  ? 19  LEU A CG  1 
ATOM 137  C CD1 . LEU A 1 20  ? 310.881 304.314 394.802 1.00 46.58  ? 19  LEU A CD1 1 
ATOM 138  C CD2 . LEU A 1 20  ? 308.487 304.968 394.704 1.00 46.58  ? 19  LEU A CD2 1 
ATOM 139  N N   . VAL A 1 21  ? 312.647 306.662 396.627 1.00 44.48  ? 20  VAL A N   1 
ATOM 140  C CA  . VAL A 1 21  ? 313.319 307.879 396.192 1.00 44.48  ? 20  VAL A CA  1 
ATOM 141  C C   . VAL A 1 21  ? 313.374 307.884 394.670 1.00 44.48  ? 20  VAL A C   1 
ATOM 142  O O   . VAL A 1 21  ? 313.771 306.890 394.050 1.00 44.48  ? 20  VAL A O   1 
ATOM 143  C CB  . VAL A 1 21  ? 314.720 308.010 396.823 1.00 44.48  ? 20  VAL A CB  1 
ATOM 144  C CG1 . VAL A 1 21  ? 315.597 306.838 396.455 1.00 44.48  ? 20  VAL A CG1 1 
ATOM 145  C CG2 . VAL A 1 21  ? 315.376 309.303 396.387 1.00 44.48  ? 20  VAL A CG2 1 
ATOM 146  N N   . LEU A 1 22  ? 312.945 308.991 394.073 1.00 41.88  ? 21  LEU A N   1 
ATOM 147  C CA  . LEU A 1 22  ? 312.812 309.124 392.631 1.00 41.88  ? 21  LEU A CA  1 
ATOM 148  C C   . LEU A 1 22  ? 313.824 310.135 392.115 1.00 41.88  ? 21  LEU A C   1 
ATOM 149  O O   . LEU A 1 22  ? 314.127 311.120 392.791 1.00 41.88  ? 21  LEU A O   1 
ATOM 150  C CB  . LEU A 1 22  ? 311.396 309.566 392.252 1.00 41.88  ? 21  LEU A CB  1 
ATOM 151  C CG  . LEU A 1 22  ? 310.246 308.602 392.537 1.00 41.88  ? 21  LEU A CG  1 
ATOM 152  C CD1 . LEU A 1 22  ? 308.924 309.280 392.274 1.00 41.88  ? 21  LEU A CD1 1 
ATOM 153  C CD2 . LEU A 1 22  ? 310.368 307.360 391.682 1.00 41.88  ? 21  LEU A CD2 1 
ATOM 154  N N   . ASN A 1 23  ? 314.346 309.890 390.920 1.00 44.03  ? 22  ASN A N   1 
ATOM 155  C CA  . ASN A 1 23  ? 315.312 310.793 390.320 1.00 44.03  ? 22  ASN A CA  1 
ATOM 156  C C   . ASN A 1 23  ? 314.770 311.379 389.023 1.00 44.03  ? 22  ASN A C   1 
ATOM 157  O O   . ASN A 1 23  ? 314.048 310.704 388.285 1.00 44.03  ? 22  ASN A O   1 
ATOM 158  C CB  . ASN A 1 23  ? 316.636 310.080 390.028 1.00 44.03  ? 22  ASN A CB  1 
ATOM 159  C CG  . ASN A 1 23  ? 317.497 309.936 391.255 1.00 44.03  ? 22  ASN A CG  1 
ATOM 160  O OD1 . ASN A 1 23  ? 317.375 310.705 392.204 1.00 44.03  ? 22  ASN A OD1 1 
ATOM 161  N ND2 . ASN A 1 23  ? 318.382 308.949 391.243 1.00 44.03  ? 22  ASN A ND2 1 
ATOM 162  N N   . PRO A 1 24  ? 315.098 312.631 388.719 1.00 40.47  ? 23  PRO A N   1 
ATOM 163  C CA  . PRO A 1 24  ? 314.595 313.246 387.488 1.00 40.47  ? 23  PRO A CA  1 
ATOM 164  C C   . PRO A 1 24  ? 315.153 312.572 386.248 1.00 40.47  ? 23  PRO A C   1 
ATOM 165  O O   . PRO A 1 24  ? 316.240 311.993 386.261 1.00 40.47  ? 23  PRO A O   1 
ATOM 166  C CB  . PRO A 1 24  ? 315.078 314.696 387.591 1.00 40.47  ? 23  PRO A CB  1 
ATOM 167  C CG  . PRO A 1 24  ? 316.169 314.673 388.594 1.00 40.47  ? 23  PRO A CG  1 
ATOM 168  C CD  . PRO A 1 24  ? 315.844 313.586 389.550 1.00 40.47  ? 23  PRO A CD  1 
ATOM 169  N N   . ARG A 1 25  ? 314.378 312.642 385.165 1.00 38.46  ? 24  ARG A N   1 
ATOM 170  C CA  . ARG A 1 25  ? 314.805 312.099 383.883 1.00 38.46  ? 24  ARG A CA  1 
ATOM 171  C C   . ARG A 1 25  ? 314.495 313.057 382.742 1.00 38.46  ? 24  ARG A C   1 
ATOM 172  O O   . ARG A 1 25  ? 314.173 312.621 381.632 1.00 38.46  ? 24  ARG A O   1 
ATOM 173  C CB  . ARG A 1 25  ? 314.155 310.745 383.611 1.00 38.46  ? 24  ARG A CB  1 
ATOM 174  C CG  . ARG A 1 25  ? 314.599 309.652 384.554 1.00 38.46  ? 24  ARG A CG  1 
ATOM 175  C CD  . ARG A 1 25  ? 315.920 309.047 384.125 1.00 38.46  ? 24  ARG A CD  1 
ATOM 176  N NE  . ARG A 1 25  ? 315.875 308.599 382.740 1.00 38.46  ? 24  ARG A NE  1 
ATOM 177  C CZ  . ARG A 1 25  ? 315.683 307.342 382.366 1.00 38.46  ? 24  ARG A CZ  1 
ATOM 178  N NH1 . ARG A 1 25  ? 315.532 306.373 383.252 1.00 38.46  ? 24  ARG A NH1 1 
ATOM 179  N NH2 . ARG A 1 25  ? 315.640 307.051 381.069 1.00 38.46  ? 24  ARG A NH2 1 
ATOM 180  N N   . GLY A 1 26  ? 314.572 314.358 382.997 1.00 39.12  ? 25  GLY A N   1 
ATOM 181  C CA  . GLY A 1 26  ? 314.354 315.346 381.962 1.00 39.12  ? 25  GLY A CA  1 
ATOM 182  C C   . GLY A 1 26  ? 312.891 315.493 381.602 1.00 39.12  ? 25  GLY A C   1 
ATOM 183  O O   . GLY A 1 26  ? 312.004 314.851 382.161 1.00 39.12  ? 25  GLY A O   1 
ATOM 184  N N   . VAL A 1 27  ? 312.640 316.367 380.631 1.00 39.19  ? 26  VAL A N   1 
ATOM 185  C CA  . VAL A 1 27  ? 311.299 316.615 380.121 1.00 39.19  ? 26  VAL A CA  1 
ATOM 186  C C   . VAL A 1 27  ? 311.284 316.300 378.633 1.00 39.19  ? 26  VAL A C   1 
ATOM 187  O O   . VAL A 1 27  ? 312.260 316.555 377.921 1.00 39.19  ? 26  VAL A O   1 
ATOM 188  C CB  . VAL A 1 27  ? 310.829 318.063 380.387 1.00 39.19  ? 26  VAL A CB  1 
ATOM 189  C CG1 . VAL A 1 27  ? 311.018 318.419 381.846 1.00 39.19  ? 26  VAL A CG1 1 
ATOM 190  C CG2 . VAL A 1 27  ? 311.558 319.046 379.504 1.00 39.19  ? 26  VAL A CG2 1 
ATOM 191  N N   . ASN A 1 28  ? 310.193 315.713 378.178 1.00 41.79  ? 27  ASN A N   1 
ATOM 192  C CA  . ASN A 1 28  ? 310.055 315.366 376.773 1.00 41.79  ? 27  ASN A CA  1 
ATOM 193  C C   . ASN A 1 28  ? 309.764 316.620 375.963 1.00 41.79  ? 27  ASN A C   1 
ATOM 194  O O   . ASN A 1 28  ? 308.758 317.289 376.220 1.00 41.79  ? 27  ASN A O   1 
ATOM 195  C CB  . ASN A 1 28  ? 308.935 314.350 376.602 1.00 41.79  ? 27  ASN A CB  1 
ATOM 196  C CG  . ASN A 1 28  ? 309.034 313.585 375.305 1.00 41.79  ? 27  ASN A CG  1 
ATOM 197  O OD1 . ASN A 1 28  ? 309.360 314.147 374.263 1.00 41.79  ? 27  ASN A OD1 1 
ATOM 198  N ND2 . ASN A 1 28  ? 308.742 312.294 375.360 1.00 41.79  ? 27  ASN A ND2 1 
ATOM 199  N N   . PRO A 1 29  ? 310.600 316.980 374.985 1.00 42.73  ? 28  PRO A N   1 
ATOM 200  C CA  . PRO A 1 29  ? 310.303 318.165 374.168 1.00 42.73  ? 28  PRO A CA  1 
ATOM 201  C C   . PRO A 1 29  ? 309.141 317.972 373.211 1.00 42.73  ? 28  PRO A C   1 
ATOM 202  O O   . PRO A 1 29  ? 308.622 318.967 372.691 1.00 42.73  ? 28  PRO A O   1 
ATOM 203  C CB  . PRO A 1 29  ? 311.611 318.401 373.410 1.00 42.73  ? 28  PRO A CB  1 
ATOM 204  C CG  . PRO A 1 29  ? 312.237 317.058 373.330 1.00 42.73  ? 28  PRO A CG  1 
ATOM 205  C CD  . PRO A 1 29  ? 311.866 316.341 374.596 1.00 42.73  ? 28  PRO A CD  1 
ATOM 206  N N   . THR A 1 30  ? 308.720 316.734 372.955 1.00 45.02  ? 29  THR A N   1 
ATOM 207  C CA  . THR A 1 30  ? 307.617 316.504 372.029 1.00 45.02  ? 29  THR A CA  1 
ATOM 208  C C   . THR A 1 30  ? 306.281 316.905 372.645 1.00 45.02  ? 29  THR A C   1 
ATOM 209  O O   . THR A 1 30  ? 305.456 317.555 371.994 1.00 45.02  ? 29  THR A O   1 
ATOM 210  C CB  . THR A 1 30  ? 307.591 315.038 371.601 1.00 45.02  ? 29  THR A CB  1 
ATOM 211  O OG1 . THR A 1 30  ? 308.802 314.725 370.903 1.00 45.02  ? 29  THR A OG1 1 
ATOM 212  C CG2 . THR A 1 30  ? 306.404 314.768 370.692 1.00 45.02  ? 29  THR A CG2 1 
ATOM 213  N N   . ASN A 1 31  ? 306.050 316.528 373.904 1.00 43.09  ? 30  ASN A N   1 
ATOM 214  C CA  . ASN A 1 31  ? 304.766 316.763 374.552 1.00 43.09  ? 30  ASN A CA  1 
ATOM 215  C C   . ASN A 1 31  ? 304.893 317.395 375.934 1.00 43.09  ? 30  ASN A C   1 
ATOM 216  O O   . ASN A 1 31  ? 303.889 317.495 376.647 1.00 43.09  ? 30  ASN A O   1 
ATOM 217  C CB  . ASN A 1 31  ? 303.974 315.456 374.641 1.00 43.09  ? 30  ASN A CB  1 
ATOM 218  C CG  . ASN A 1 31  ? 304.738 314.360 375.350 1.00 43.09  ? 30  ASN A CG  1 
ATOM 219  O OD1 . ASN A 1 31  ? 305.826 314.586 375.873 1.00 43.09  ? 30  ASN A OD1 1 
ATOM 220  N ND2 . ASN A 1 31  ? 304.176 313.159 375.361 1.00 43.09  ? 30  ASN A ND2 1 
ATOM 221  N N   . GLY A 1 32  ? 306.088 317.819 376.331 1.00 42.17  ? 31  GLY A N   1 
ATOM 222  C CA  . GLY A 1 32  ? 306.257 318.530 377.589 1.00 42.17  ? 31  GLY A CA  1 
ATOM 223  C C   . GLY A 1 32  ? 305.908 317.728 378.822 1.00 42.17  ? 31  GLY A C   1 
ATOM 224  O O   . GLY A 1 32  ? 305.330 318.273 379.769 1.00 42.17  ? 31  GLY A O   1 
ATOM 225  N N   . VAL A 1 33  ? 306.253 316.447 378.840 1.00 37.13  ? 32  VAL A N   1 
ATOM 226  C CA  . VAL A 1 33  ? 305.944 315.562 379.955 1.00 37.13  ? 32  VAL A CA  1 
ATOM 227  C C   . VAL A 1 33  ? 307.219 315.361 380.761 1.00 37.13  ? 32  VAL A C   1 
ATOM 228  O O   . VAL A 1 33  ? 308.179 314.752 380.279 1.00 37.13  ? 32  VAL A O   1 
ATOM 229  C CB  . VAL A 1 33  ? 305.380 314.222 379.470 1.00 37.13  ? 32  VAL A CB  1 
ATOM 230  C CG1 . VAL A 1 33  ? 305.303 313.241 380.616 1.00 37.13  ? 32  VAL A CG1 1 
ATOM 231  C CG2 . VAL A 1 33  ? 304.018 314.418 378.850 1.00 37.13  ? 32  VAL A CG2 1 
ATOM 232  N N   . ALA A 1 34  ? 307.236 315.866 381.990 1.00 35.47  ? 33  ALA A N   1 
ATOM 233  C CA  . ALA A 1 34  ? 308.351 315.600 382.883 1.00 35.47  ? 33  ALA A CA  1 
ATOM 234  C C   . ALA A 1 34  ? 308.276 314.170 383.396 1.00 35.47  ? 33  ALA A C   1 
ATOM 235  O O   . ALA A 1 34  ? 307.197 313.590 383.521 1.00 35.47  ? 33  ALA A O   1 
ATOM 236  C CB  . ALA A 1 34  ? 308.348 316.579 384.055 1.00 35.47  ? 33  ALA A CB  1 
ATOM 237  N N   . SER A 1 35  ? 309.437 313.597 383.687 1.00 37.93  ? 34  SER A N   1 
ATOM 238  C CA  . SER A 1 35  ? 309.517 312.216 384.132 1.00 37.93  ? 34  SER A CA  1 
ATOM 239  C C   . SER A 1 35  ? 310.373 312.116 385.382 1.00 37.93  ? 34  SER A C   1 
ATOM 240  O O   . SER A 1 35  ? 311.334 312.866 385.562 1.00 37.93  ? 34  SER A O   1 
ATOM 241  C CB  . SER A 1 35  ? 310.093 311.307 383.046 1.00 37.93  ? 34  SER A CB  1 
ATOM 242  O OG  . SER A 1 35  ? 309.467 311.544 381.800 1.00 37.93  ? 34  SER A OG  1 
ATOM 243  N N   . LEU A 1 36  ? 310.009 311.178 386.244 1.00 37.74  ? 35  LEU A N   1 
ATOM 244  C CA  . LEU A 1 36  ? 310.788 310.827 387.418 1.00 37.74  ? 35  LEU A CA  1 
ATOM 245  C C   . LEU A 1 36  ? 310.960 309.320 387.428 1.00 37.74  ? 35  LEU A C   1 
ATOM 246  O O   . LEU A 1 36  ? 310.044 308.584 387.055 1.00 37.74  ? 35  LEU A O   1 
ATOM 247  C CB  . LEU A 1 36  ? 310.118 311.291 388.708 1.00 37.74  ? 35  LEU A CB  1 
ATOM 248  C CG  . LEU A 1 36  ? 310.184 312.785 389.009 1.00 37.74  ? 35  LEU A CG  1 
ATOM 249  C CD1 . LEU A 1 36  ? 309.012 313.508 388.376 1.00 37.74  ? 35  LEU A CD1 1 
ATOM 250  C CD2 . LEU A 1 36  ? 310.214 313.012 390.501 1.00 37.74  ? 35  LEU A CD2 1 
ATOM 251  N N   . SER A 1 37  ? 312.133 308.862 387.835 1.00 41.72  ? 36  SER A N   1 
ATOM 252  C CA  . SER A 1 37  ? 312.456 307.449 387.787 1.00 41.72  ? 36  SER A CA  1 
ATOM 253  C C   . SER A 1 37  ? 313.082 307.013 389.100 1.00 41.72  ? 36  SER A C   1 
ATOM 254  O O   . SER A 1 37  ? 313.717 307.808 389.796 1.00 41.72  ? 36  SER A O   1 
ATOM 255  C CB  . SER A 1 37  ? 313.400 307.146 386.637 1.00 41.72  ? 36  SER A CB  1 
ATOM 256  O OG  . SER A 1 37  ? 313.735 305.780 386.614 1.00 41.72  ? 36  SER A OG  1 
ATOM 257  N N   . GLN A 1 38  ? 312.899 305.737 389.427 1.00 45.51  ? 37  GLN A N   1 
ATOM 258  C CA  . GLN A 1 38  ? 313.396 305.205 390.688 1.00 45.51  ? 37  GLN A CA  1 
ATOM 259  C C   . GLN A 1 38  ? 314.916 305.263 390.741 1.00 45.51  ? 37  GLN A C   1 
ATOM 260  O O   . GLN A 1 38  ? 315.599 304.856 389.798 1.00 45.51  ? 37  GLN A O   1 
ATOM 261  C CB  . GLN A 1 38  ? 312.917 303.768 390.874 1.00 45.51  ? 37  GLN A CB  1 
ATOM 262  C CG  . GLN A 1 38  ? 313.281 303.168 392.213 1.00 45.51  ? 37  GLN A CG  1 
ATOM 263  C CD  . GLN A 1 38  ? 312.958 301.694 392.293 1.00 45.51  ? 37  GLN A CD  1 
ATOM 264  O OE1 . GLN A 1 38  ? 312.812 301.024 391.275 1.00 45.51  ? 37  GLN A OE1 1 
ATOM 265  N NE2 . GLN A 1 38  ? 312.844 301.180 393.509 1.00 45.51  ? 37  GLN A NE2 1 
ATOM 266  N N   . ALA A 1 39  ? 315.444 305.764 391.854 1.00 47.38  ? 38  ALA A N   1 
ATOM 267  C CA  . ALA A 1 39  ? 316.887 305.843 392.025 1.00 47.38  ? 38  ALA A CA  1 
ATOM 268  C C   . ALA A 1 39  ? 317.488 304.446 392.081 1.00 47.38  ? 38  ALA A C   1 
ATOM 269  O O   . ALA A 1 39  ? 316.898 303.519 392.640 1.00 47.38  ? 38  ALA A O   1 
ATOM 270  C CB  . ALA A 1 39  ? 317.234 306.616 393.295 1.00 47.38  ? 38  ALA A CB  1 
ATOM 271  N N   . GLY A 1 40  ? 318.679 304.302 391.508 1.00 50.69  ? 39  GLY A N   1 
ATOM 272  C CA  . GLY A 1 40  ? 319.216 302.970 391.344 1.00 50.69  ? 39  GLY A CA  1 
ATOM 273  C C   . GLY A 1 40  ? 318.458 302.231 390.256 1.00 50.69  ? 39  GLY A C   1 
ATOM 274  O O   . GLY A 1 40  ? 317.941 302.827 389.306 1.00 50.69  ? 39  GLY A O   1 
ATOM 275  N N   . ALA A 1 41  ? 318.400 300.906 390.397 1.00 50.76  ? 40  ALA A N   1 
ATOM 276  C CA  . ALA A 1 41  ? 317.660 300.043 389.482 1.00 50.76  ? 40  ALA A CA  1 
ATOM 277  C C   . ALA A 1 41  ? 318.166 300.158 388.050 1.00 50.76  ? 40  ALA A C   1 
ATOM 278  O O   . ALA A 1 41  ? 319.134 300.873 387.777 1.00 50.76  ? 40  ALA A O   1 
ATOM 279  C CB  . ALA A 1 41  ? 316.163 300.356 389.536 1.00 50.76  ? 40  ALA A CB  1 
ATOM 280  N N   . VAL A 1 42  ? 317.523 299.450 387.130 1.00 48.97  ? 41  VAL A N   1 
ATOM 281  C CA  . VAL A 1 42  ? 317.922 299.472 385.725 1.00 48.97  ? 41  VAL A CA  1 
ATOM 282  C C   . VAL A 1 42  ? 316.706 299.848 384.893 1.00 48.97  ? 41  VAL A C   1 
ATOM 283  O O   . VAL A 1 42  ? 315.558 299.676 385.332 1.00 48.97  ? 41  VAL A O   1 
ATOM 284  C CB  . VAL A 1 42  ? 318.510 298.114 385.275 1.00 48.97  ? 41  VAL A CB  1 
ATOM 285  C CG1 . VAL A 1 42  ? 319.581 297.652 386.242 1.00 48.97  ? 41  VAL A CG1 1 
ATOM 286  C CG2 . VAL A 1 42  ? 317.419 297.075 385.147 1.00 48.97  ? 41  VAL A CG2 1 
ATOM 287  N N   . PRO A 1 43  ? 316.919 300.385 383.694 1.00 49.56  ? 42  PRO A N   1 
ATOM 288  C CA  . PRO A 1 43  ? 315.782 300.703 382.827 1.00 49.56  ? 42  PRO A CA  1 
ATOM 289  C C   . PRO A 1 43  ? 314.977 299.456 382.498 1.00 49.56  ? 42  PRO A C   1 
ATOM 290  O O   . PRO A 1 43  ? 315.495 298.338 382.489 1.00 49.56  ? 42  PRO A O   1 
ATOM 291  C CB  . PRO A 1 43  ? 316.443 301.295 381.578 1.00 49.56  ? 42  PRO A CB  1 
ATOM 292  C CG  . PRO A 1 43  ? 317.750 301.818 382.066 1.00 49.56  ? 42  PRO A CG  1 
ATOM 293  C CD  . PRO A 1 43  ? 318.192 300.861 383.125 1.00 49.56  ? 42  PRO A CD  1 
ATOM 294  N N   . ALA A 1 44  ? 313.683 299.661 382.264 1.00 52.75  ? 43  ALA A N   1 
ATOM 295  C CA  . ALA A 1 44  ? 312.705 298.613 381.987 1.00 52.75  ? 43  ALA A CA  1 
ATOM 296  C C   . ALA A 1 44  ? 312.492 297.677 383.169 1.00 52.75  ? 43  ALA A C   1 
ATOM 297  O O   . ALA A 1 44  ? 311.879 296.616 383.010 1.00 52.75  ? 43  ALA A O   1 
ATOM 298  C CB  . ALA A 1 44  ? 313.080 297.797 380.741 1.00 52.75  ? 43  ALA A CB  1 
ATOM 299  N N   . LEU A 1 45  ? 312.987 298.037 384.354 1.00 50.88  ? 44  LEU A N   1 
ATOM 300  C CA  . LEU A 1 45  ? 312.762 297.229 385.546 1.00 50.88  ? 44  LEU A CA  1 
ATOM 301  C C   . LEU A 1 45  ? 312.501 298.098 386.771 1.00 50.88  ? 44  LEU A C   1 
ATOM 302  O O   . LEU A 1 45  ? 312.834 297.692 387.889 1.00 50.88  ? 44  LEU A O   1 
ATOM 303  C CB  . LEU A 1 45  ? 313.957 296.309 385.802 1.00 50.88  ? 44  LEU A CB  1 
ATOM 304  C CG  . LEU A 1 45  ? 313.699 294.965 386.477 1.00 50.88  ? 44  LEU A CG  1 
ATOM 305  C CD1 . LEU A 1 45  ? 312.894 294.061 385.563 1.00 50.88  ? 44  LEU A CD1 1 
ATOM 306  C CD2 . LEU A 1 45  ? 315.010 294.311 386.856 1.00 50.88  ? 44  LEU A CD2 1 
ATOM 307  N N   . GLU A 1 46  ? 311.917 299.280 386.596 1.00 46.77  ? 45  GLU A N   1 
ATOM 308  C CA  . GLU A 1 46  ? 311.885 300.283 387.647 1.00 46.77  ? 45  GLU A CA  1 
ATOM 309  C C   . GLU A 1 46  ? 310.581 301.067 387.598 1.00 46.77  ? 45  GLU A C   1 
ATOM 310  O O   . GLU A 1 46  ? 309.834 301.020 386.619 1.00 46.77  ? 45  GLU A O   1 
ATOM 311  C CB  . GLU A 1 46  ? 313.085 301.217 387.520 1.00 46.77  ? 45  GLU A CB  1 
ATOM 312  C CG  . GLU A 1 46  ? 313.112 301.944 386.200 1.00 46.77  ? 45  GLU A CG  1 
ATOM 313  C CD  . GLU A 1 46  ? 314.145 303.036 386.168 1.00 46.77  ? 45  GLU A CD  1 
ATOM 314  O OE1 . GLU A 1 46  ? 314.165 303.804 385.185 1.00 46.77  ? 45  GLU A OE1 1 
ATOM 315  O OE2 . GLU A 1 46  ? 314.936 303.137 387.126 1.00 46.77  ? 45  GLU A OE2 1 
ATOM 316  N N   . LYS A 1 47  ? 310.321 301.797 388.679 1.00 42.27  ? 46  LYS A N   1 
ATOM 317  C CA  . LYS A 1 47  ? 309.103 302.577 388.820 1.00 42.27  ? 46  LYS A CA  1 
ATOM 318  C C   . LYS A 1 47  ? 309.248 303.931 388.139 1.00 42.27  ? 46  LYS A C   1 
ATOM 319  O O   . LYS A 1 47  ? 310.313 304.551 388.165 1.00 42.27  ? 46  LYS A O   1 
ATOM 320  C CB  . LYS A 1 47  ? 308.774 302.768 390.298 1.00 42.27  ? 46  LYS A CB  1 
ATOM 321  C CG  . LYS A 1 47  ? 308.732 301.470 391.073 1.00 42.27  ? 46  LYS A CG  1 
ATOM 322  C CD  . LYS A 1 47  ? 308.482 301.700 392.544 1.00 42.27  ? 46  LYS A CD  1 
ATOM 323  C CE  . LYS A 1 47  ? 308.194 300.390 393.249 1.00 42.27  ? 46  LYS A CE  1 
ATOM 324  N NZ  . LYS A 1 47  ? 309.347 299.460 393.192 1.00 42.27  ? 46  LYS A NZ  1 
ATOM 325  N N   . ARG A 1 48  ? 308.159 304.392 387.530 1.00 39.10  ? 47  ARG A N   1 
ATOM 326  C CA  . ARG A 1 48  ? 308.158 305.634 386.772 1.00 39.10  ? 47  ARG A CA  1 
ATOM 327  C C   . ARG A 1 48  ? 306.984 306.502 387.191 1.00 39.10  ? 47  ARG A C   1 
ATOM 328  O O   . ARG A 1 48  ? 305.919 306.000 387.555 1.00 39.10  ? 47  ARG A O   1 
ATOM 329  C CB  . ARG A 1 48  ? 308.082 305.371 385.268 1.00 39.10  ? 47  ARG A CB  1 
ATOM 330  C CG  . ARG A 1 48  ? 309.015 304.283 384.781 1.00 39.10  ? 47  ARG A CG  1 
ATOM 331  C CD  . ARG A 1 48  ? 309.668 304.661 383.470 1.00 39.10  ? 47  ARG A CD  1 
ATOM 332  N NE  . ARG A 1 48  ? 308.685 304.902 382.423 1.00 39.10  ? 47  ARG A NE  1 
ATOM 333  C CZ  . ARG A 1 48  ? 308.554 306.049 381.770 1.00 39.10  ? 47  ARG A CZ  1 
ATOM 334  N NH1 . ARG A 1 48  ? 309.332 307.087 382.032 1.00 39.10  ? 47  ARG A NH1 1 
ATOM 335  N NH2 . ARG A 1 48  ? 307.618 306.158 380.831 1.00 39.10  ? 47  ARG A NH2 1 
ATOM 336  N N   . VAL A 1 49  ? 307.192 307.815 387.143 1.00 32.11  ? 48  VAL A N   1 
ATOM 337  C CA  . VAL A 1 49  ? 306.150 308.804 387.401 1.00 32.11  ? 48  VAL A CA  1 
ATOM 338  C C   . VAL A 1 49  ? 306.263 309.884 386.336 1.00 32.11  ? 48  VAL A C   1 
ATOM 339  O O   . VAL A 1 49  ? 307.368 310.341 386.031 1.00 32.11  ? 48  VAL A O   1 
ATOM 340  C CB  . VAL A 1 49  ? 306.280 309.426 388.805 1.00 32.11  ? 48  VAL A CB  1 
ATOM 341  C CG1 . VAL A 1 49  ? 305.223 310.485 389.016 1.00 32.11  ? 48  VAL A CG1 1 
ATOM 342  C CG2 . VAL A 1 49  ? 306.191 308.362 389.874 1.00 32.11  ? 48  VAL A CG2 1 
ATOM 343  N N   . THR A 1 50  ? 305.134 310.288 385.760 1.00 31.52  ? 49  THR A N   1 
ATOM 344  C CA  . THR A 1 50  ? 305.116 311.352 384.764 1.00 31.52  ? 49  THR A CA  1 
ATOM 345  C C   . THR A 1 50  ? 304.145 312.431 385.207 1.00 31.52  ? 49  THR A C   1 
ATOM 346  O O   . THR A 1 50  ? 303.019 312.127 385.609 1.00 31.52  ? 49  THR A O   1 
ATOM 347  C CB  . THR A 1 50  ? 304.713 310.832 383.383 1.00 31.52  ? 49  THR A CB  1 
ATOM 348  O OG1 . THR A 1 50  ? 303.390 310.293 383.442 1.00 31.52  ? 49  THR A OG1 1 
ATOM 349  C CG2 . THR A 1 50  ? 305.669 309.746 382.926 1.00 31.52  ? 49  THR A CG2 1 
ATOM 350  N N   . VAL A 1 51  ? 304.578 313.685 385.134 1.00 30.89  ? 50  VAL A N   1 
ATOM 351  C CA  . VAL A 1 51  ? 303.757 314.831 385.502 1.00 30.89  ? 50  VAL A CA  1 
ATOM 352  C C   . VAL A 1 51  ? 303.718 315.787 384.322 1.00 30.89  ? 50  VAL A C   1 
ATOM 353  O O   . VAL A 1 51  ? 304.764 316.116 383.754 1.00 30.89  ? 50  VAL A O   1 
ATOM 354  C CB  . VAL A 1 51  ? 304.302 315.547 386.751 1.00 30.89  ? 50  VAL A CB  1 
ATOM 355  C CG1 . VAL A 1 51  ? 303.293 316.555 387.263 1.00 30.89  ? 50  VAL A CG1 1 
ATOM 356  C CG2 . VAL A 1 51  ? 304.653 314.543 387.827 1.00 30.89  ? 50  VAL A CG2 1 
ATOM 357  N N   . SER A 1 52  ? 302.521 316.232 383.951 1.00 32.58  ? 51  SER A N   1 
ATOM 358  C CA  . SER A 1 52  ? 302.374 317.203 382.879 1.00 32.58  ? 51  SER A CA  1 
ATOM 359  C C   . SER A 1 52  ? 301.357 318.258 383.280 1.00 32.58  ? 51  SER A C   1 
ATOM 360  O O   . SER A 1 52  ? 300.419 317.986 384.031 1.00 32.58  ? 51  SER A O   1 
ATOM 361  C CB  . SER A 1 52  ? 301.933 316.553 381.566 1.00 32.58  ? 51  SER A CB  1 
ATOM 362  O OG  . SER A 1 52  ? 300.534 316.347 381.551 1.00 32.58  ? 51  SER A OG  1 
ATOM 363  N N   . VAL A 1 53  ? 301.559 319.470 382.777 1.00 38.70  ? 52  VAL A N   1 
ATOM 364  C CA  . VAL A 1 53  ? 300.602 320.559 382.911 1.00 38.70  ? 52  VAL A CA  1 
ATOM 365  C C   . VAL A 1 53  ? 300.331 321.103 381.519 1.00 38.70  ? 52  VAL A C   1 
ATOM 366  O O   . VAL A 1 53  ? 301.254 321.244 380.710 1.00 38.70  ? 52  VAL A O   1 
ATOM 367  C CB  . VAL A 1 53  ? 301.117 321.673 383.843 1.00 38.70  ? 52  VAL A CB  1 
ATOM 368  C CG1 . VAL A 1 53  ? 300.013 322.664 384.136 1.00 38.70  ? 52  VAL A CG1 1 
ATOM 369  C CG2 . VAL A 1 53  ? 301.660 321.083 385.127 1.00 38.70  ? 52  VAL A CG2 1 
ATOM 370  N N   . SER A 1 54  ? 299.069 321.395 381.233 1.00 51.53  ? 53  SER A N   1 
ATOM 371  C CA  . SER A 1 54  ? 298.650 321.772 379.894 1.00 51.53  ? 53  SER A CA  1 
ATOM 372  C C   . SER A 1 54  ? 298.088 323.186 379.888 1.00 51.53  ? 53  SER A C   1 
ATOM 373  O O   . SER A 1 54  ? 297.604 323.694 380.901 1.00 51.53  ? 53  SER A O   1 
ATOM 374  C CB  . SER A 1 54  ? 297.607 320.793 379.347 1.00 51.53  ? 53  SER A CB  1 
ATOM 375  O OG  . SER A 1 54  ? 297.180 321.174 378.053 1.00 51.53  ? 53  SER A OG  1 
ATOM 376  N N   . GLN A 1 55  ? 298.167 323.816 378.721 1.00 65.16  ? 54  GLN A N   1 
ATOM 377  C CA  . GLN A 1 55  ? 297.724 325.171 378.452 1.00 65.16  ? 54  GLN A CA  1 
ATOM 378  C C   . GLN A 1 55  ? 296.414 325.159 377.672 1.00 65.16  ? 54  GLN A C   1 
ATOM 379  O O   . GLN A 1 55  ? 296.161 324.239 376.889 1.00 65.16  ? 54  GLN A O   1 
ATOM 380  C CB  . GLN A 1 55  ? 298.779 325.937 377.645 1.00 65.16  ? 54  GLN A CB  1 
ATOM 381  C CG  . GLN A 1 55  ? 300.109 326.126 378.354 1.00 65.16  ? 54  GLN A CG  1 
ATOM 382  C CD  . GLN A 1 55  ? 300.009 327.052 379.544 1.00 65.16  ? 54  GLN A CD  1 
ATOM 383  O OE1 . GLN A 1 55  ? 299.302 328.058 379.503 1.00 65.16  ? 54  GLN A OE1 1 
ATOM 384  N NE2 . GLN A 1 55  ? 300.718 326.718 380.615 1.00 65.16  ? 54  GLN A NE2 1 
ATOM 385  N N   . PRO A 1 56  ? 295.558 326.161 377.863 1.00 68.40  ? 55  PRO A N   1 
ATOM 386  C CA  . PRO A 1 56  ? 294.336 326.243 377.058 1.00 68.40  ? 55  PRO A CA  1 
ATOM 387  C C   . PRO A 1 56  ? 294.666 326.477 375.593 1.00 68.40  ? 55  PRO A C   1 
ATOM 388  O O   . PRO A 1 56  ? 295.650 327.137 375.252 1.00 68.40  ? 55  PRO A O   1 
ATOM 389  C CB  . PRO A 1 56  ? 293.593 327.437 377.664 1.00 68.40  ? 55  PRO A CB  1 
ATOM 390  C CG  . PRO A 1 56  ? 294.656 328.252 378.300 1.00 68.40  ? 55  PRO A CG  1 
ATOM 391  C CD  . PRO A 1 56  ? 295.670 327.277 378.812 1.00 68.40  ? 55  PRO A CD  1 
ATOM 392  N N   . SER A 1 57  ? 293.827 325.928 374.721 1.00 80.37  ? 56  SER A N   1 
ATOM 393  C CA  . SER A 1 57  ? 294.052 326.011 373.285 1.00 80.37  ? 56  SER A CA  1 
ATOM 394  C C   . SER A 1 57  ? 292.701 326.137 372.590 1.00 80.37  ? 56  SER A C   1 
ATOM 395  O O   . SER A 1 57  ? 291.674 326.405 373.221 1.00 80.37  ? 56  SER A O   1 
ATOM 396  C CB  . SER A 1 57  ? 294.848 324.798 372.789 1.00 80.37  ? 56  SER A CB  1 
ATOM 397  O OG  . SER A 1 57  ? 295.042 324.856 371.387 1.00 80.37  ? 56  SER A OG  1 
ATOM 398  N N   . ARG A 1 58  ? 292.707 325.948 371.270 1.00 84.28  ? 57  ARG A N   1 
ATOM 399  C CA  . ARG A 1 58  ? 291.477 326.083 370.499 1.00 84.28  ? 57  ARG A CA  1 
ATOM 400  C C   . ARG A 1 58  ? 290.562 324.880 370.684 1.00 84.28  ? 57  ARG A C   1 
ATOM 401  O O   . ARG A 1 58  ? 289.364 324.965 370.392 1.00 84.28  ? 57  ARG A O   1 
ATOM 402  C CB  . ARG A 1 58  ? 291.806 326.286 369.020 1.00 84.28  ? 57  ARG A CB  1 
ATOM 403  C CG  . ARG A 1 58  ? 291.967 327.746 368.620 1.00 84.28  ? 57  ARG A CG  1 
ATOM 404  C CD  . ARG A 1 58  ? 293.212 328.360 369.242 1.00 84.28  ? 57  ARG A CD  1 
ATOM 405  N NE  . ARG A 1 58  ? 293.424 329.735 368.807 1.00 84.28  ? 57  ARG A NE  1 
ATOM 406  C CZ  . ARG A 1 58  ? 294.353 330.541 369.303 1.00 84.28  ? 57  ARG A CZ  1 
ATOM 407  N NH1 . ARG A 1 58  ? 295.174 330.141 370.262 1.00 84.28  ? 57  ARG A NH1 1 
ATOM 408  N NH2 . ARG A 1 58  ? 294.461 331.778 368.827 1.00 84.28  ? 57  ARG A NH2 1 
ATOM 409  N N   . ASN A 1 59  ? 291.101 323.756 371.158 1.00 81.07  ? 58  ASN A N   1 
ATOM 410  C CA  . ASN A 1 59  ? 290.270 322.583 371.399 1.00 81.07  ? 58  ASN A CA  1 
ATOM 411  C C   . ASN A 1 59  ? 289.704 322.580 372.813 1.00 81.07  ? 58  ASN A C   1 
ATOM 412  O O   . ASN A 1 59  ? 288.514 322.306 373.007 1.00 81.07  ? 58  ASN A O   1 
ATOM 413  C CB  . ASN A 1 59  ? 291.075 321.310 371.143 1.00 81.07  ? 58  ASN A CB  1 
ATOM 414  C CG  . ASN A 1 59  ? 291.522 321.185 369.702 1.00 81.07  ? 58  ASN A CG  1 
ATOM 415  O OD1 . ASN A 1 59  ? 292.324 321.983 369.217 1.00 81.07  ? 58  ASN A OD1 1 
ATOM 416  N ND2 . ASN A 1 59  ? 291.005 320.178 369.007 1.00 81.07  ? 58  ASN A ND2 1 
ATOM 417  N N   . ARG A 1 60  ? 290.534 322.885 373.808 1.00 74.26  ? 59  ARG A N   1 
ATOM 418  C CA  . ARG A 1 60  ? 290.115 322.927 375.201 1.00 74.26  ? 59  ARG A CA  1 
ATOM 419  C C   . ARG A 1 60  ? 290.365 324.318 375.761 1.00 74.26  ? 59  ARG A C   1 
ATOM 420  O O   . ARG A 1 60  ? 291.423 324.909 375.529 1.00 74.26  ? 59  ARG A O   1 
ATOM 421  C CB  . ARG A 1 60  ? 290.858 321.883 376.037 1.00 74.26  ? 59  ARG A CB  1 
ATOM 422  C CG  . ARG A 1 60  ? 290.914 320.502 375.402 1.00 74.26  ? 59  ARG A CG  1 
ATOM 423  C CD  . ARG A 1 60  ? 292.058 319.661 375.962 1.00 74.26  ? 59  ARG A CD  1 
ATOM 424  N NE  . ARG A 1 60  ? 293.349 320.334 375.876 1.00 74.26  ? 59  ARG A NE  1 
ATOM 425  C CZ  . ARG A 1 60  ? 293.938 320.965 376.883 1.00 74.26  ? 59  ARG A CZ  1 
ATOM 426  N NH1 . ARG A 1 60  ? 293.380 321.025 378.081 1.00 74.26  ? 59  ARG A NH1 1 
ATOM 427  N NH2 . ARG A 1 60  ? 295.113 321.552 376.683 1.00 74.26  ? 59  ARG A NH2 1 
ATOM 428  N N   . LYS A 1 61  ? 289.387 324.833 376.507 1.00 71.23  ? 60  LYS A N   1 
ATOM 429  C CA  . LYS A 1 61  ? 289.426 326.189 377.036 1.00 71.23  ? 60  LYS A CA  1 
ATOM 430  C C   . LYS A 1 61  ? 289.833 326.235 378.504 1.00 71.23  ? 60  LYS A C   1 
ATOM 431  O O   . LYS A 1 61  ? 289.694 327.281 379.147 1.00 71.23  ? 60  LYS A O   1 
ATOM 432  C CB  . LYS A 1 61  ? 288.067 326.864 376.848 1.00 71.23  ? 60  LYS A CB  1 
ATOM 433  C CG  . LYS A 1 61  ? 287.463 326.682 375.465 1.00 71.23  ? 60  LYS A CG  1 
ATOM 434  C CD  . LYS A 1 61  ? 288.360 327.265 374.385 1.00 71.23  ? 60  LYS A CD  1 
ATOM 435  C CE  . LYS A 1 61  ? 288.357 326.400 373.135 1.00 71.23  ? 60  LYS A CE  1 
ATOM 436  N NZ  . LYS A 1 61  ? 287.010 326.330 372.505 1.00 71.23  ? 60  LYS A NZ  1 
ATOM 437  N N   . ASN A 1 62  ? 290.338 325.131 379.046 1.00 56.63  ? 61  ASN A N   1 
ATOM 438  C CA  . ASN A 1 62  ? 290.628 325.039 380.467 1.00 56.63  ? 61  ASN A CA  1 
ATOM 439  C C   . ASN A 1 62  ? 291.914 324.255 380.678 1.00 56.63  ? 61  ASN A C   1 
ATOM 440  O O   . ASN A 1 62  ? 292.377 323.533 379.793 1.00 56.63  ? 61  ASN A O   1 
ATOM 441  C CB  . ASN A 1 62  ? 289.468 324.383 381.218 1.00 56.63  ? 61  ASN A CB  1 
ATOM 442  C CG  . ASN A 1 62  ? 289.038 323.080 380.595 1.00 56.63  ? 61  ASN A CG  1 
ATOM 443  O OD1 . ASN A 1 62  ? 289.595 322.649 379.587 1.00 56.63  ? 61  ASN A OD1 1 
ATOM 444  N ND2 . ASN A 1 62  ? 288.044 322.438 381.192 1.00 56.63  ? 61  ASN A ND2 1 
ATOM 445  N N   . TYR A 1 63  ? 292.493 324.410 381.865 1.00 47.82  ? 62  TYR A N   1 
ATOM 446  C CA  . TYR A 1 63  ? 293.760 323.764 382.161 1.00 47.82  ? 62  TYR A CA  1 
ATOM 447  C C   . TYR A 1 63  ? 293.549 322.275 382.406 1.00 47.82  ? 62  TYR A C   1 
ATOM 448  O O   . TYR A 1 63  ? 292.429 321.804 382.607 1.00 47.82  ? 62  TYR A O   1 
ATOM 449  C CB  . TYR A 1 63  ? 294.427 324.394 383.381 1.00 47.82  ? 62  TYR A CB  1 
ATOM 450  C CG  . TYR A 1 63  ? 295.075 325.730 383.113 1.00 47.82  ? 62  TYR A CG  1 
ATOM 451  C CD1 . TYR A 1 63  ? 294.462 326.674 382.307 1.00 47.82  ? 62  TYR A CD1 1 
ATOM 452  C CD2 . TYR A 1 63  ? 296.332 326.020 383.611 1.00 47.82  ? 62  TYR A CD2 1 
ATOM 453  C CE1 . TYR A 1 63  ? 295.054 327.888 382.057 1.00 47.82  ? 62  TYR A CE1 1 
ATOM 454  C CE2 . TYR A 1 63  ? 296.937 327.230 383.357 1.00 47.82  ? 62  TYR A CE2 1 
ATOM 455  C CZ  . TYR A 1 63  ? 296.294 328.158 382.575 1.00 47.82  ? 62  TYR A CZ  1 
ATOM 456  O OH  . TYR A 1 63  ? 296.893 329.368 382.316 1.00 47.82  ? 62  TYR A OH  1 
ATOM 457  N N   . LYS A 1 64  ? 294.649 321.527 382.385 1.00 39.68  ? 63  LYS A N   1 
ATOM 458  C CA  . LYS A 1 64  ? 294.581 320.088 382.611 1.00 39.68  ? 63  LYS A CA  1 
ATOM 459  C C   . LYS A 1 64  ? 295.914 319.601 383.151 1.00 39.68  ? 63  LYS A C   1 
ATOM 460  O O   . LYS A 1 64  ? 296.921 319.643 382.442 1.00 39.68  ? 63  LYS A O   1 
ATOM 461  C CB  . LYS A 1 64  ? 294.222 319.351 381.324 1.00 39.68  ? 63  LYS A CB  1 
ATOM 462  C CG  . LYS A 1 64  ? 293.773 317.925 381.540 1.00 39.68  ? 63  LYS A CG  1 
ATOM 463  C CD  . LYS A 1 64  ? 293.765 317.154 380.239 1.00 39.68  ? 63  LYS A CD  1 
ATOM 464  C CE  . LYS A 1 64  ? 295.176 316.841 379.776 1.00 39.68  ? 63  LYS A CE  1 
ATOM 465  N NZ  . LYS A 1 64  ? 295.716 315.624 380.440 1.00 39.68  ? 63  LYS A NZ  1 
ATOM 466  N N   . VAL A 1 65  ? 295.913 319.127 384.393 1.00 31.21  ? 64  VAL A N   1 
ATOM 467  C CA  . VAL A 1 65  ? 297.086 318.546 385.031 1.00 31.21  ? 64  VAL A CA  1 
ATOM 468  C C   . VAL A 1 65  ? 296.880 317.042 385.108 1.00 31.21  ? 64  VAL A C   1 
ATOM 469  O O   . VAL A 1 65  ? 295.826 316.580 385.555 1.00 31.21  ? 64  VAL A O   1 
ATOM 470  C CB  . VAL A 1 65  ? 297.318 319.139 386.430 1.00 31.21  ? 64  VAL A CB  1 
ATOM 471  C CG1 . VAL A 1 65  ? 298.462 318.429 387.122 1.00 31.21  ? 64  VAL A CG1 1 
ATOM 472  C CG2 . VAL A 1 65  ? 297.588 320.622 386.332 1.00 31.21  ? 64  VAL A CG2 1 
ATOM 473  N N   . GLN A 1 66  ? 297.879 316.280 384.673 1.00 31.33  ? 65  GLN A N   1 
ATOM 474  C CA  . GLN A 1 66  ? 297.766 314.830 384.609 1.00 31.33  ? 65  GLN A CA  1 
ATOM 475  C C   . GLN A 1 66  ? 299.011 314.180 385.190 1.00 31.33  ? 65  GLN A C   1 
ATOM 476  O O   . GLN A 1 66  ? 300.131 314.506 384.789 1.00 31.33  ? 65  GLN A O   1 
ATOM 477  C CB  . GLN A 1 66  ? 297.548 314.372 383.170 1.00 31.33  ? 65  GLN A CB  1 
ATOM 478  C CG  . GLN A 1 66  ? 297.332 312.890 383.026 1.00 31.33  ? 65  GLN A CG  1 
ATOM 479  C CD  . GLN A 1 66  ? 297.059 312.491 381.599 1.00 31.33  ? 65  GLN A CD  1 
ATOM 480  O OE1 . GLN A 1 66  ? 297.067 313.326 380.699 1.00 31.33  ? 65  GLN A OE1 1 
ATOM 481  N NE2 . GLN A 1 66  ? 296.809 311.207 381.381 1.00 31.33  ? 65  GLN A NE2 1 
ATOM 482  N N   . VAL A 1 67  ? 298.809 313.257 386.125 1.00 27.94  ? 66  VAL A N   1 
ATOM 483  C CA  . VAL A 1 67  ? 299.883 312.521 386.776 1.00 27.94  ? 66  VAL A CA  1 
ATOM 484  C C   . VAL A 1 67  ? 299.657 311.041 386.523 1.00 27.94  ? 66  VAL A C   1 
ATOM 485  O O   . VAL A 1 67  ? 298.559 310.532 386.763 1.00 27.94  ? 66  VAL A O   1 
ATOM 486  C CB  . VAL A 1 67  ? 299.931 312.809 388.286 1.00 27.94  ? 66  VAL A CB  1 
ATOM 487  C CG1 . VAL A 1 67  ? 300.932 311.902 388.965 1.00 27.94  ? 66  VAL A CG1 1 
ATOM 488  C CG2 . VAL A 1 67  ? 300.270 314.257 388.528 1.00 27.94  ? 66  VAL A CG2 1 
ATOM 489  N N   . LYS A 1 68  ? 300.686 310.354 386.040 1.00 29.07  ? 67  LYS A N   1 
ATOM 490  C CA  . LYS A 1 68  ? 300.601 308.931 385.747 1.00 29.07  ? 67  LYS A CA  1 
ATOM 491  C C   . LYS A 1 68  ? 301.767 308.220 386.412 1.00 29.07  ? 67  LYS A C   1 
ATOM 492  O O   . LYS A 1 68  ? 302.918 308.627 386.242 1.00 29.07  ? 67  LYS A O   1 
ATOM 493  C CB  . LYS A 1 68  ? 300.618 308.680 384.238 1.00 29.07  ? 67  LYS A CB  1 
ATOM 494  C CG  . LYS A 1 68  ? 299.363 309.137 383.529 1.00 29.07  ? 67  LYS A CG  1 
ATOM 495  C CD  . LYS A 1 68  ? 299.583 309.283 382.040 1.00 29.07  ? 67  LYS A CD  1 
ATOM 496  C CE  . LYS A 1 68  ? 299.375 307.968 381.319 1.00 29.07  ? 67  LYS A CE  1 
ATOM 497  N NZ  . LYS A 1 68  ? 299.212 308.167 379.854 1.00 29.07  ? 67  LYS A NZ  1 
ATOM 498  N N   . ILE A 1 69  ? 301.473 307.166 387.169 1.00 30.41  ? 68  ILE A N   1 
ATOM 499  C CA  . ILE A 1 69  ? 302.497 306.353 387.810 1.00 30.41  ? 68  ILE A CA  1 
ATOM 500  C C   . ILE A 1 69  ? 302.281 304.904 387.404 1.00 30.41  ? 68  ILE A C   1 
ATOM 501  O O   . ILE A 1 69  ? 301.144 304.424 387.361 1.00 30.41  ? 68  ILE A O   1 
ATOM 502  C CB  . ILE A 1 69  ? 302.490 306.501 389.347 1.00 30.41  ? 68  ILE A CB  1 
ATOM 503  C CG1 . ILE A 1 69  ? 301.182 306.026 389.954 1.00 30.41  ? 68  ILE A CG1 1 
ATOM 504  C CG2 . ILE A 1 69  ? 302.648 307.945 389.738 1.00 30.41  ? 68  ILE A CG2 1 
ATOM 505  C CD1 . ILE A 1 69  ? 301.234 305.942 391.458 1.00 30.41  ? 68  ILE A CD1 1 
ATOM 506  N N   . GLN A 1 70  ? 303.369 304.217 387.073 1.00 35.71  ? 69  GLN A N   1 
ATOM 507  C CA  . GLN A 1 70  ? 303.292 302.817 386.681 1.00 35.71  ? 69  GLN A CA  1 
ATOM 508  C C   . GLN A 1 70  ? 304.565 302.119 387.127 1.00 35.71  ? 69  GLN A C   1 
ATOM 509  O O   . GLN A 1 70  ? 305.650 302.696 387.047 1.00 35.71  ? 69  GLN A O   1 
ATOM 510  C CB  . GLN A 1 70  ? 303.091 302.668 385.169 1.00 35.71  ? 69  GLN A CB  1 
ATOM 511  C CG  . GLN A 1 70  ? 304.266 303.096 384.318 1.00 35.71  ? 69  GLN A CG  1 
ATOM 512  C CD  . GLN A 1 70  ? 305.098 301.920 383.861 1.00 35.71  ? 69  GLN A CD  1 
ATOM 513  O OE1 . GLN A 1 70  ? 304.585 300.818 383.686 1.00 35.71  ? 69  GLN A OE1 1 
ATOM 514  N NE2 . GLN A 1 70  ? 306.390 302.147 383.662 1.00 35.71  ? 69  GLN A NE2 1 
ATOM 515  N N   . ASN A 1 71  ? 304.426 300.886 387.612 1.00 39.10  ? 70  ASN A N   1 
ATOM 516  C CA  . ASN A 1 71  ? 305.561 300.156 388.138 1.00 39.10  ? 70  ASN A CA  1 
ATOM 517  C C   . ASN A 1 71  ? 305.451 298.643 387.972 1.00 39.10  ? 70  ASN A C   1 
ATOM 518  O O   . ASN A 1 71  ? 304.392 298.060 388.254 1.00 39.10  ? 70  ASN A O   1 
ATOM 519  C CB  . ASN A 1 71  ? 305.770 300.545 389.606 1.00 39.10  ? 70  ASN A CB  1 
ATOM 520  C CG  . ASN A 1 71  ? 304.575 300.252 390.484 1.00 39.10  ? 70  ASN A CG  1 
ATOM 521  O OD1 . ASN A 1 71  ? 303.595 299.659 390.055 1.00 39.10  ? 70  ASN A OD1 1 
ATOM 522  N ND2 . ASN A 1 71  ? 304.652 300.687 391.733 1.00 39.10  ? 70  ASN A ND2 1 
ATOM 523  N N   . PRO A 1 72  ? 306.501 297.990 387.489 1.00 45.92  ? 71  PRO A N   1 
ATOM 524  C CA  . PRO A 1 72  ? 306.421 296.569 387.154 1.00 45.92  ? 71  PRO A CA  1 
ATOM 525  C C   . PRO A 1 72  ? 306.868 295.666 388.297 1.00 45.92  ? 71  PRO A C   1 
ATOM 526  O O   . PRO A 1 72  ? 307.372 296.115 389.327 1.00 45.92  ? 71  PRO A O   1 
ATOM 527  C CB  . PRO A 1 72  ? 307.385 296.456 385.971 1.00 45.92  ? 71  PRO A CB  1 
ATOM 528  C CG  . PRO A 1 72  ? 308.430 297.458 386.279 1.00 45.92  ? 71  PRO A CG  1 
ATOM 529  C CD  . PRO A 1 72  ? 307.760 298.588 387.022 1.00 45.92  ? 71  PRO A CD  1 
ATOM 530  N N   . THR A 1 73  ? 306.672 294.368 388.084 1.00 58.13  ? 72  THR A N   1 
ATOM 531  C CA  . THR A 1 73  ? 307.112 293.327 389.001 1.00 58.13  ? 72  THR A CA  1 
ATOM 532  C C   . THR A 1 73  ? 308.062 292.400 388.260 1.00 58.13  ? 72  THR A C   1 
ATOM 533  O O   . THR A 1 73  ? 307.751 291.940 387.158 1.00 58.13  ? 72  THR A O   1 
ATOM 534  C CB  . THR A 1 73  ? 305.925 292.539 389.556 1.00 58.13  ? 72  THR A CB  1 
ATOM 535  O OG1 . THR A 1 73  ? 305.006 293.440 390.186 1.00 58.13  ? 72  THR A OG1 1 
ATOM 536  C CG2 . THR A 1 73  ? 306.393 291.517 390.572 1.00 58.13  ? 72  THR A CG2 1 
ATOM 537  N N   . ALA A 1 74  ? 309.214 292.128 388.864 1.00 70.73  ? 73  ALA A N   1 
ATOM 538  C CA  . ALA A 1 74  ? 310.273 291.359 388.227 1.00 70.73  ? 73  ALA A CA  1 
ATOM 539  C C   . ALA A 1 74  ? 310.286 289.937 388.769 1.00 70.73  ? 73  ALA A C   1 
ATOM 540  O O   . ALA A 1 74  ? 310.232 289.730 389.985 1.00 70.73  ? 73  ALA A O   1 
ATOM 541  C CB  . ALA A 1 74  ? 311.632 292.020 388.452 1.00 70.73  ? 73  ALA A CB  1 
ATOM 542  N N   . CYS A 1 75  ? 310.361 288.963 387.865 1.00 84.31  ? 74  CYS A N   1 
ATOM 543  C CA  . CYS A 1 75  ? 310.448 287.555 388.227 1.00 84.31  ? 74  CYS A CA  1 
ATOM 544  C C   . CYS A 1 75  ? 311.649 286.937 387.530 1.00 84.31  ? 74  CYS A C   1 
ATOM 545  O O   . CYS A 1 75  ? 311.822 287.108 386.319 1.00 84.31  ? 74  CYS A O   1 
ATOM 546  C CB  . CYS A 1 75  ? 309.171 286.803 387.844 1.00 84.31  ? 74  CYS A CB  1 
ATOM 547  S SG  . CYS A 1 75  ? 309.257 285.012 388.077 1.00 84.31  ? 74  CYS A SG  1 
ATOM 548  N N   . THR A 1 76  ? 312.468 286.215 388.288 1.00 88.48  ? 75  THR A N   1 
ATOM 549  C CA  . THR A 1 76  ? 313.661 285.569 387.759 1.00 88.48  ? 75  THR A CA  1 
ATOM 550  C C   . THR A 1 76  ? 313.422 284.071 387.630 1.00 88.48  ? 75  THR A C   1 
ATOM 551  O O   . THR A 1 76  ? 312.959 283.426 388.577 1.00 88.48  ? 75  THR A O   1 
ATOM 552  C CB  . THR A 1 76  ? 314.870 285.832 388.656 1.00 88.48  ? 75  THR A CB  1 
ATOM 553  O OG1 . THR A 1 76  ? 314.862 287.200 389.082 1.00 88.48  ? 75  THR A OG1 1 
ATOM 554  C CG2 . THR A 1 76  ? 316.159 285.553 387.898 1.00 88.48  ? 75  THR A CG2 1 
ATOM 555  N N   . ALA A 1 77  ? 313.741 283.523 386.462 1.00 90.89  ? 76  ALA A N   1 
ATOM 556  C CA  . ALA A 1 77  ? 313.545 282.103 386.205 1.00 90.89  ? 76  ALA A CA  1 
ATOM 557  C C   . ALA A 1 77  ? 314.875 281.359 386.203 1.00 90.89  ? 76  ALA A C   1 
ATOM 558  O O   . ALA A 1 77  ? 315.601 281.370 385.209 1.00 90.89  ? 76  ALA A O   1 
ATOM 559  C CB  . ALA A 1 77  ? 312.825 281.900 384.884 1.00 90.89  ? 76  ALA A CB  1 
ATOM 560  N N   . SER A 1 80  ? 317.242 282.841 383.620 1.00 98.82  ? 79  SER A N   1 
ATOM 561  C CA  . SER A 1 80  ? 318.410 283.456 383.002 1.00 98.82  ? 79  SER A CA  1 
ATOM 562  C C   . SER A 1 80  ? 319.149 284.356 383.985 1.00 98.82  ? 79  SER A C   1 
ATOM 563  O O   . SER A 1 80  ? 318.875 284.340 385.183 1.00 98.82  ? 79  SER A O   1 
ATOM 564  C CB  . SER A 1 80  ? 318.003 284.257 381.766 1.00 98.82  ? 79  SER A CB  1 
ATOM 565  O OG  . SER A 1 80  ? 319.137 284.818 381.129 1.00 98.82  ? 79  SER A OG  1 
ATOM 566  N N   . CYS A 1 81  ? 320.095 285.139 383.465 1.00 99.74  ? 80  CYS A N   1 
ATOM 567  C CA  . CYS A 1 81  ? 320.846 286.061 384.311 1.00 99.74  ? 80  CYS A CA  1 
ATOM 568  C C   . CYS A 1 81  ? 320.011 287.272 384.705 1.00 99.74  ? 80  CYS A C   1 
ATOM 569  O O   . CYS A 1 81  ? 320.070 287.721 385.855 1.00 99.74  ? 80  CYS A O   1 
ATOM 570  C CB  . CYS A 1 81  ? 322.121 286.509 383.596 1.00 99.74  ? 80  CYS A CB  1 
ATOM 571  S SG  . CYS A 1 81  ? 323.426 285.260 383.530 1.00 99.74  ? 80  CYS A SG  1 
ATOM 572  N N   . ASP A 1 82  ? 319.227 287.811 383.770 1.00 92.97  ? 81  ASP A N   1 
ATOM 573  C CA  . ASP A 1 82  ? 318.498 289.044 384.011 1.00 92.97  ? 81  ASP A CA  1 
ATOM 574  C C   . ASP A 1 82  ? 317.025 288.777 384.301 1.00 92.97  ? 81  ASP A C   1 
ATOM 575  O O   . ASP A 1 82  ? 316.453 287.796 383.817 1.00 92.97  ? 81  ASP A O   1 
ATOM 576  C CB  . ASP A 1 82  ? 318.638 289.990 382.811 1.00 92.97  ? 81  ASP A CB  1 
ATOM 577  C CG  . ASP A 1 82  ? 318.270 289.335 381.488 1.00 92.97  ? 81  ASP A CG  1 
ATOM 578  O OD1 . ASP A 1 82  ? 317.551 288.317 381.477 1.00 92.97  ? 81  ASP A OD1 1 
ATOM 579  O OD2 . ASP A 1 82  ? 318.716 289.845 380.440 1.00 92.97  ? 81  ASP A OD2 1 
ATOM 580  N N   . PRO A 1 83  ? 316.392 289.622 385.110 1.00 80.79  ? 82  PRO A N   1 
ATOM 581  C CA  . PRO A 1 83  ? 314.974 289.427 385.422 1.00 80.79  ? 82  PRO A CA  1 
ATOM 582  C C   . PRO A 1 83  ? 314.092 289.789 384.239 1.00 80.79  ? 82  PRO A C   1 
ATOM 583  O O   . PRO A 1 83  ? 314.531 290.352 383.236 1.00 80.79  ? 82  PRO A O   1 
ATOM 584  C CB  . PRO A 1 83  ? 314.734 290.367 386.606 1.00 80.79  ? 82  PRO A CB  1 
ATOM 585  C CG  . PRO A 1 83  ? 316.095 290.673 387.144 1.00 80.79  ? 82  PRO A CG  1 
ATOM 586  C CD  . PRO A 1 83  ? 316.994 290.665 385.953 1.00 80.79  ? 82  PRO A CD  1 
ATOM 587  N N   . SER A 1 84  ? 312.816 289.443 384.372 1.00 74.52  ? 83  SER A N   1 
ATOM 588  C CA  . SER A 1 84  ? 311.807 289.757 383.374 1.00 74.52  ? 83  SER A CA  1 
ATOM 589  C C   . SER A 1 84  ? 310.564 290.286 384.071 1.00 74.52  ? 83  SER A C   1 
ATOM 590  O O   . SER A 1 84  ? 310.301 289.962 385.232 1.00 74.52  ? 83  SER A O   1 
ATOM 591  C CB  . SER A 1 84  ? 311.451 288.534 382.526 1.00 74.52  ? 83  SER A CB  1 
ATOM 592  O OG  . SER A 1 84  ? 310.849 287.527 383.320 1.00 74.52  ? 83  SER A OG  1 
ATOM 593  N N   . VAL A 1 85  ? 309.802 291.104 383.355 1.00 65.60  ? 84  VAL A N   1 
ATOM 594  C CA  . VAL A 1 85  ? 308.596 291.713 383.904 1.00 65.60  ? 84  VAL A CA  1 
ATOM 595  C C   . VAL A 1 85  ? 307.439 290.735 383.752 1.00 65.60  ? 84  VAL A C   1 
ATOM 596  O O   . VAL A 1 85  ? 307.234 290.153 382.682 1.00 65.60  ? 84  VAL A O   1 
ATOM 597  C CB  . VAL A 1 85  ? 308.289 293.057 383.226 1.00 65.60  ? 84  VAL A CB  1 
ATOM 598  C CG1 . VAL A 1 85  ? 309.371 294.062 383.558 1.00 65.60  ? 84  VAL A CG1 1 
ATOM 599  C CG2 . VAL A 1 85  ? 308.177 292.892 381.721 1.00 65.60  ? 84  VAL A CG2 1 
ATOM 600  N N   . THR A 1 86  ? 306.698 290.532 384.838 1.00 61.00  ? 85  THR A N   1 
ATOM 601  C CA  . THR A 1 86  ? 305.545 289.645 384.831 1.00 61.00  ? 85  THR A CA  1 
ATOM 602  C C   . THR A 1 86  ? 304.239 290.410 384.666 1.00 61.00  ? 85  THR A C   1 
ATOM 603  O O   . THR A 1 86  ? 303.368 289.995 383.894 1.00 61.00  ? 85  THR A O   1 
ATOM 604  C CB  . THR A 1 86  ? 305.508 288.826 386.123 1.00 61.00  ? 85  THR A CB  1 
ATOM 605  O OG1 . THR A 1 86  ? 306.721 288.076 386.246 1.00 61.00  ? 85  THR A OG1 1 
ATOM 606  C CG2 . THR A 1 86  ? 304.333 287.868 386.117 1.00 61.00  ? 85  THR A CG2 1 
ATOM 607  N N   . ARG A 1 87  ? 304.097 291.528 385.369 1.00 52.51  ? 86  ARG A N   1 
ATOM 608  C CA  . ARG A 1 87  ? 302.874 292.314 385.344 1.00 52.51  ? 86  ARG A CA  1 
ATOM 609  C C   . ARG A 1 87  ? 303.221 293.737 385.747 1.00 52.51  ? 86  ARG A C   1 
ATOM 610  O O   . ARG A 1 87  ? 304.297 294.005 386.284 1.00 52.51  ? 86  ARG A O   1 
ATOM 611  C CB  . ARG A 1 87  ? 301.820 291.725 386.279 1.00 52.51  ? 86  ARG A CB  1 
ATOM 612  C CG  . ARG A 1 87  ? 302.228 291.780 387.732 1.00 52.51  ? 86  ARG A CG  1 
ATOM 613  C CD  . ARG A 1 87  ? 301.305 290.965 388.600 1.00 52.51  ? 86  ARG A CD  1 
ATOM 614  N NE  . ARG A 1 87  ? 301.932 290.631 389.871 1.00 52.51  ? 86  ARG A NE  1 
ATOM 615  C CZ  . ARG A 1 87  ? 302.468 289.452 390.149 1.00 52.51  ? 86  ARG A CZ  1 
ATOM 616  N NH1 . ARG A 1 87  ? 302.465 288.468 389.268 1.00 52.51  ? 86  ARG A NH1 1 
ATOM 617  N NH2 . ARG A 1 87  ? 303.021 289.257 391.342 1.00 52.51  ? 86  ARG A NH2 1 
ATOM 618  N N   . GLN A 1 88  ? 302.294 294.653 385.478 1.00 41.99  ? 87  GLN A N   1 
ATOM 619  C CA  . GLN A 1 88  ? 302.477 296.051 385.831 1.00 41.99  ? 87  GLN A CA  1 
ATOM 620  C C   . GLN A 1 88  ? 301.194 296.606 386.425 1.00 41.99  ? 87  GLN A C   1 
ATOM 621  O O   . GLN A 1 88  ? 300.090 296.234 386.022 1.00 41.99  ? 87  GLN A O   1 
ATOM 622  C CB  . GLN A 1 88  ? 302.898 296.884 384.620 1.00 41.99  ? 87  GLN A CB  1 
ATOM 623  C CG  . GLN A 1 88  ? 304.293 296.573 384.129 1.00 41.99  ? 87  GLN A CG  1 
ATOM 624  C CD  . GLN A 1 88  ? 304.634 297.304 382.857 1.00 41.99  ? 87  GLN A CD  1 
ATOM 625  O OE1 . GLN A 1 88  ? 304.652 296.717 381.776 1.00 41.99  ? 87  GLN A OE1 1 
ATOM 626  N NE2 . GLN A 1 88  ? 304.908 298.594 382.975 1.00 41.99  ? 87  GLN A NE2 1 
ATOM 627  N N   . ALA A 1 89  ? 301.354 297.509 387.385 1.00 36.36  ? 88  ALA A N   1 
ATOM 628  C CA  . ALA A 1 89  ? 300.244 298.191 388.031 1.00 36.36  ? 88  ALA A CA  1 
ATOM 629  C C   . ALA A 1 89  ? 300.277 299.663 387.654 1.00 36.36  ? 88  ALA A C   1 
ATOM 630  O O   . ALA A 1 89  ? 301.299 300.330 387.837 1.00 36.36  ? 88  ALA A O   1 
ATOM 631  C CB  . ALA A 1 89  ? 300.312 298.033 389.550 1.00 36.36  ? 88  ALA A CB  1 
ATOM 632  N N   . TYR A 1 90  ? 299.164 300.166 387.135 1.00 32.51  ? 89  TYR A N   1 
ATOM 633  C CA  . TYR A 1 90  ? 299.058 301.547 386.697 1.00 32.51  ? 89  TYR A CA  1 
ATOM 634  C C   . TYR A 1 90  ? 298.181 302.345 387.650 1.00 32.51  ? 89  TYR A C   1 
ATOM 635  O O   . TYR A 1 90  ? 297.454 301.792 388.477 1.00 32.51  ? 89  TYR A O   1 
ATOM 636  C CB  . TYR A 1 90  ? 298.485 301.636 385.280 1.00 32.51  ? 89  TYR A CB  1 
ATOM 637  C CG  . TYR A 1 90  ? 299.212 300.795 384.261 1.00 32.51  ? 89  TYR A CG  1 
ATOM 638  C CD1 . TYR A 1 90  ? 298.849 299.480 384.033 1.00 32.51  ? 89  TYR A CD1 1 
ATOM 639  C CD2 . TYR A 1 90  ? 300.257 301.321 383.522 1.00 32.51  ? 89  TYR A CD2 1 
ATOM 640  C CE1 . TYR A 1 90  ? 299.508 298.711 383.100 1.00 32.51  ? 89  TYR A CE1 1 
ATOM 641  C CE2 . TYR A 1 90  ? 300.923 300.560 382.588 1.00 32.51  ? 89  TYR A CE2 1 
ATOM 642  C CZ  . TYR A 1 90  ? 300.545 299.255 382.380 1.00 32.51  ? 89  TYR A CZ  1 
ATOM 643  O OH  . TYR A 1 90  ? 301.204 298.489 381.449 1.00 32.51  ? 89  TYR A OH  1 
ATOM 644  N N   . ALA A 1 91  ? 298.271 303.665 387.522 1.00 27.87  ? 90  ALA A N   1 
ATOM 645  C CA  . ALA A 1 91  ? 297.462 304.611 388.275 1.00 27.87  ? 90  ALA A CA  1 
ATOM 646  C C   . ALA A 1 91  ? 297.659 305.982 387.658 1.00 27.87  ? 90  ALA A C   1 
ATOM 647  O O   . ALA A 1 91  ? 298.786 306.354 387.331 1.00 27.87  ? 90  ALA A O   1 
ATOM 648  C CB  . ALA A 1 91  ? 297.852 304.637 389.756 1.00 27.87  ? 90  ALA A CB  1 
ATOM 649  N N   . ASP A 1 92  ? 296.569 306.727 387.490 1.00 29.79  ? 91  ASP A N   1 
ATOM 650  C CA  . ASP A 1 92  ? 296.693 308.058 386.920 1.00 29.79  ? 91  ASP A CA  1 
ATOM 651  C C   . ASP A 1 92  ? 295.650 308.988 387.518 1.00 29.79  ? 91  ASP A C   1 
ATOM 652  O O   . ASP A 1 92  ? 294.563 308.561 387.910 1.00 29.79  ? 91  ASP A O   1 
ATOM 653  C CB  . ASP A 1 92  ? 296.583 308.025 385.392 1.00 29.79  ? 91  ASP A CB  1 
ATOM 654  C CG  . ASP A 1 92  ? 295.235 307.563 384.908 1.00 29.79  ? 91  ASP A CG  1 
ATOM 655  O OD1 . ASP A 1 92  ? 295.180 306.501 384.256 1.00 29.79  ? 91  ASP A OD1 1 
ATOM 656  O OD2 . ASP A 1 92  ? 294.236 308.275 385.133 1.00 29.79  ? 91  ASP A OD2 1 
ATOM 657  N N   . VAL A 1 93  ? 296.001 310.269 387.576 1.00 29.17  ? 92  VAL A N   1 
ATOM 658  C CA  . VAL A 1 93  ? 295.133 311.323 388.079 1.00 29.17  ? 92  VAL A CA  1 
ATOM 659  C C   . VAL A 1 93  ? 295.042 312.398 387.010 1.00 29.17  ? 92  VAL A C   1 
ATOM 660  O O   . VAL A 1 93  ? 296.010 312.641 386.283 1.00 29.17  ? 92  VAL A O   1 
ATOM 661  C CB  . VAL A 1 93  ? 295.664 311.921 389.397 1.00 29.17  ? 92  VAL A CB  1 
ATOM 662  C CG1 . VAL A 1 93  ? 294.600 312.762 390.064 1.00 29.17  ? 92  VAL A CG1 1 
ATOM 663  C CG2 . VAL A 1 93  ? 296.145 310.828 390.322 1.00 29.17  ? 92  VAL A CG2 1 
ATOM 664  N N   . THR A 1 94  ? 293.880 313.036 386.900 1.00 29.76  ? 93  THR A N   1 
ATOM 665  C CA  . THR A 1 94  ? 293.694 314.113 385.929 1.00 29.76  ? 93  THR A CA  1 
ATOM 666  C C   . THR A 1 94  ? 292.735 315.164 386.486 1.00 29.76  ? 93  THR A C   1 
ATOM 667  O O   . THR A 1 94  ? 291.513 315.019 386.416 1.00 29.76  ? 93  THR A O   1 
ATOM 668  C CB  . THR A 1 94  ? 293.243 313.556 384.577 1.00 29.76  ? 93  THR A CB  1 
ATOM 669  O OG1 . THR A 1 94  ? 293.152 314.613 383.613 1.00 29.76  ? 93  THR A OG1 1 
ATOM 670  C CG2 . THR A 1 94  ? 291.945 312.759 384.657 1.00 29.76  ? 93  THR A CG2 1 
ATOM 671  N N   . PHE A 1 95  ? 293.304 316.221 387.057 1.00 31.18  ? 94  PHE A N   1 
ATOM 672  C CA  . PHE A 1 95  ? 292.531 317.382 387.462 1.00 31.18  ? 94  PHE A CA  1 
ATOM 673  C C   . PHE A 1 95  ? 292.164 318.212 386.242 1.00 31.18  ? 94  PHE A C   1 
ATOM 674  O O   . PHE A 1 95  ? 292.822 318.148 385.201 1.00 31.18  ? 94  PHE A O   1 
ATOM 675  C CB  . PHE A 1 95  ? 293.318 318.241 388.446 1.00 31.18  ? 94  PHE A CB  1 
ATOM 676  C CG  . PHE A 1 95  ? 293.896 317.476 389.594 1.00 31.18  ? 94  PHE A CG  1 
ATOM 677  C CD1 . PHE A 1 95  ? 295.104 316.822 389.468 1.00 31.18  ? 94  PHE A CD1 1 
ATOM 678  C CD2 . PHE A 1 95  ? 293.242 317.431 390.809 1.00 31.18  ? 94  PHE A CD2 1 
ATOM 679  C CE1 . PHE A 1 95  ? 295.638 316.125 390.525 1.00 31.18  ? 94  PHE A CE1 1 
ATOM 680  C CE2 . PHE A 1 95  ? 293.773 316.738 391.867 1.00 31.18  ? 94  PHE A CE2 1 
ATOM 681  C CZ  . PHE A 1 95  ? 294.971 316.084 391.725 1.00 31.18  ? 94  PHE A CZ  1 
ATOM 682  N N   . SER A 1 96  ? 291.101 318.999 386.373 1.00 34.71  ? 95  SER A N   1 
ATOM 683  C CA  . SER A 1 96  ? 290.628 319.837 385.272 1.00 34.71  ? 95  SER A CA  1 
ATOM 684  C C   . SER A 1 96  ? 290.011 321.096 385.868 1.00 34.71  ? 95  SER A C   1 
ATOM 685  O O   . SER A 1 96  ? 288.837 321.103 386.241 1.00 34.71  ? 95  SER A O   1 
ATOM 686  C CB  . SER A 1 96  ? 289.631 319.089 384.401 1.00 34.71  ? 95  SER A CB  1 
ATOM 687  O OG  . SER A 1 96  ? 289.349 319.811 383.219 1.00 34.71  ? 95  SER A OG  1 
ATOM 688  N N   . PHE A 1 97  ? 290.803 322.155 385.948 1.00 38.44  ? 96  PHE A N   1 
ATOM 689  C CA  . PHE A 1 97  ? 290.363 323.449 386.439 1.00 38.44  ? 96  PHE A CA  1 
ATOM 690  C C   . PHE A 1 97  ? 290.085 324.367 385.256 1.00 38.44  ? 96  PHE A C   1 
ATOM 691  O O   . PHE A 1 97  ? 290.293 324.001 384.101 1.00 38.44  ? 96  PHE A O   1 
ATOM 692  C CB  . PHE A 1 97  ? 291.416 324.041 387.372 1.00 38.44  ? 96  PHE A CB  1 
ATOM 693  C CG  . PHE A 1 97  ? 291.904 323.079 388.407 1.00 38.44  ? 96  PHE A CG  1 
ATOM 694  C CD1 . PHE A 1 97  ? 291.054 322.617 389.392 1.00 38.44  ? 96  PHE A CD1 1 
ATOM 695  C CD2 . PHE A 1 97  ? 293.208 322.625 388.387 1.00 38.44  ? 96  PHE A CD2 1 
ATOM 696  C CE1 . PHE A 1 97  ? 291.497 321.729 390.342 1.00 38.44  ? 96  PHE A CE1 1 
ATOM 697  C CE2 . PHE A 1 97  ? 293.657 321.738 389.336 1.00 38.44  ? 96  PHE A CE2 1 
ATOM 698  C CZ  . PHE A 1 97  ? 292.799 321.289 390.316 1.00 38.44  ? 96  PHE A CZ  1 
ATOM 699  N N   . THR A 1 98  ? 289.620 325.575 385.553 1.00 43.80  ? 97  THR A N   1 
ATOM 700  C CA  . THR A 1 98  ? 289.291 326.550 384.526 1.00 43.80  ? 97  THR A CA  1 
ATOM 701  C C   . THR A 1 98  ? 290.096 327.821 384.753 1.00 43.80  ? 97  THR A C   1 
ATOM 702  O O   . THR A 1 98  ? 290.680 328.031 385.818 1.00 43.80  ? 97  THR A O   1 
ATOM 703  C CB  . THR A 1 98  ? 287.793 326.875 384.501 1.00 43.80  ? 97  THR A CB  1 
ATOM 704  O OG1 . THR A 1 98  ? 287.516 327.761 383.412 1.00 43.80  ? 97  THR A OG1 1 
ATOM 705  C CG2 . THR A 1 98  ? 287.368 327.535 385.792 1.00 43.80  ? 97  THR A CG2 1 
ATOM 706  N N   . GLN A 1 99  ? 290.123 328.671 383.724 1.00 45.24  ? 98  GLN A N   1 
ATOM 707  C CA  . GLN A 1 99  ? 290.971 329.857 383.744 1.00 45.24  ? 98  GLN A CA  1 
ATOM 708  C C   . GLN A 1 99  ? 290.539 330.880 384.785 1.00 45.24  ? 98  GLN A C   1 
ATOM 709  O O   . GLN A 1 99  ? 291.349 331.728 385.168 1.00 45.24  ? 98  GLN A O   1 
ATOM 710  C CB  . GLN A 1 99  ? 290.984 330.512 382.367 1.00 45.24  ? 98  GLN A CB  1 
ATOM 711  C CG  . GLN A 1 99  ? 289.631 331.046 381.950 1.00 45.24  ? 98  GLN A CG  1 
ATOM 712  C CD  . GLN A 1 99  ? 289.679 331.812 380.649 1.00 45.24  ? 98  GLN A CD  1 
ATOM 713  O OE1 . GLN A 1 99  ? 290.750 332.032 380.083 1.00 45.24  ? 98  GLN A OE1 1 
ATOM 714  N NE2 . GLN A 1 99  ? 288.516 332.224 380.164 1.00 45.24  ? 98  GLN A NE2 1 
ATOM 715  N N   . TYR A 1 100 ? 289.289 330.838 385.237 1.00 45.24  ? 99  TYR A N   1 
ATOM 716  C CA  . TYR A 1 100 ? 288.793 331.774 386.237 1.00 45.24  ? 99  TYR A CA  1 
ATOM 717  C C   . TYR A 1 100 ? 288.831 331.199 387.643 1.00 45.24  ? 99  TYR A C   1 
ATOM 718  O O   . TYR A 1 100 ? 288.334 331.836 388.575 1.00 45.24  ? 99  TYR A O   1 
ATOM 719  C CB  . TYR A 1 100 ? 287.372 332.211 385.889 1.00 45.24  ? 99  TYR A CB  1 
ATOM 720  C CG  . TYR A 1 100 ? 287.321 333.277 384.823 1.00 45.24  ? 99  TYR A CG  1 
ATOM 721  C CD1 . TYR A 1 100 ? 287.721 334.575 385.095 1.00 45.24  ? 99  TYR A CD1 1 
ATOM 722  C CD2 . TYR A 1 100 ? 286.887 332.980 383.544 1.00 45.24  ? 99  TYR A CD2 1 
ATOM 723  C CE1 . TYR A 1 100 ? 287.682 335.547 384.124 1.00 45.24  ? 99  TYR A CE1 1 
ATOM 724  C CE2 . TYR A 1 100 ? 286.844 333.946 382.567 1.00 45.24  ? 99  TYR A CE2 1 
ATOM 725  C CZ  . TYR A 1 100 ? 287.241 335.228 382.862 1.00 45.24  ? 99  TYR A CZ  1 
ATOM 726  O OH  . TYR A 1 100 ? 287.198 336.193 381.885 1.00 45.24  ? 99  TYR A OH  1 
ATOM 727  N N   . SER A 1 101 ? 289.409 330.016 387.818 1.00 45.30  ? 100 SER A N   1 
ATOM 728  C CA  . SER A 1 101 ? 289.450 329.372 389.120 1.00 45.30  ? 100 SER A CA  1 
ATOM 729  C C   . SER A 1 101 ? 290.537 329.984 389.991 1.00 45.30  ? 100 SER A C   1 
ATOM 730  O O   . SER A 1 101 ? 291.629 330.301 389.517 1.00 45.30  ? 100 SER A O   1 
ATOM 731  C CB  . SER A 1 101 ? 289.697 327.876 388.961 1.00 45.30  ? 100 SER A CB  1 
ATOM 732  O OG  . SER A 1 101 ? 291.038 327.635 388.582 1.00 45.30  ? 100 SER A OG  1 
ATOM 733  N N   . THR A 1 102 ? 290.231 330.143 391.273 1.00 49.00  ? 101 THR A N   1 
ATOM 734  C CA  . THR A 1 102 ? 291.180 330.692 392.226 1.00 49.00  ? 101 THR A CA  1 
ATOM 735  C C   . THR A 1 102 ? 292.050 329.588 392.816 1.00 49.00  ? 101 THR A C   1 
ATOM 736  O O   . THR A 1 102 ? 291.850 328.399 392.569 1.00 49.00  ? 101 THR A O   1 
ATOM 737  C CB  . THR A 1 102 ? 290.452 331.443 393.337 1.00 49.00  ? 101 THR A CB  1 
ATOM 738  O OG1 . THR A 1 102 ? 289.857 330.504 394.239 1.00 49.00  ? 101 THR A OG1 1 
ATOM 739  C CG2 . THR A 1 102 ? 289.371 332.327 392.753 1.00 49.00  ? 101 THR A CG2 1 
ATOM 740  N N   . ASP A 1 103 ? 293.037 330.003 393.608 1.00 52.52  ? 102 ASP A N   1 
ATOM 741  C CA  . ASP A 1 103 ? 293.962 329.051 394.212 1.00 52.52  ? 102 ASP A CA  1 
ATOM 742  C C   . ASP A 1 103 ? 293.296 328.225 395.305 1.00 52.52  ? 102 ASP A C   1 
ATOM 743  O O   . ASP A 1 103 ? 293.675 327.067 395.526 1.00 52.52  ? 102 ASP A O   1 
ATOM 744  C CB  . ASP A 1 103 ? 295.172 329.795 394.770 1.00 52.52  ? 102 ASP A CB  1 
ATOM 745  C CG  . ASP A 1 103 ? 296.236 328.864 395.286 1.00 52.52  ? 102 ASP A CG  1 
ATOM 746  O OD1 . ASP A 1 103 ? 296.936 328.250 394.456 1.00 52.52  ? 102 ASP A OD1 1 
ATOM 747  O OD2 . ASP A 1 103 ? 296.378 328.746 396.521 1.00 52.52  ? 102 ASP A OD2 1 
ATOM 748  N N   . GLU A 1 104 ? 292.311 328.804 395.995 1.00 52.08  ? 103 GLU A N   1 
ATOM 749  C CA  . GLU A 1 104 ? 291.636 328.100 397.080 1.00 52.08  ? 103 GLU A CA  1 
ATOM 750  C C   . GLU A 1 104 ? 290.983 326.818 396.587 1.00 52.08  ? 103 GLU A C   1 
ATOM 751  O O   . GLU A 1 104 ? 291.101 325.766 397.222 1.00 52.08  ? 103 GLU A O   1 
ATOM 752  C CB  . GLU A 1 104 ? 290.590 329.013 397.719 1.00 52.08  ? 103 GLU A CB  1 
ATOM 753  C CG  . GLU A 1 104 ? 291.137 330.046 398.687 1.00 52.08  ? 103 GLU A CG  1 
ATOM 754  C CD  . GLU A 1 104 ? 291.978 329.434 399.788 1.00 52.08  ? 103 GLU A CD  1 
ATOM 755  O OE1 . GLU A 1 104 ? 293.159 329.122 399.537 1.00 52.08  ? 103 GLU A OE1 1 
ATOM 756  O OE2 . GLU A 1 104 ? 291.456 329.263 400.909 1.00 52.08  ? 103 GLU A OE2 1 
ATOM 757  N N   . GLU A 1 105 ? 290.287 326.888 395.454 1.00 51.54  ? 104 GLU A N   1 
ATOM 758  C CA  . GLU A 1 105 ? 289.576 325.720 394.948 1.00 51.54  ? 104 GLU A CA  1 
ATOM 759  C C   . GLU A 1 105 ? 290.539 324.624 394.511 1.00 51.54  ? 104 GLU A C   1 
ATOM 760  O O   . GLU A 1 105 ? 290.303 323.440 394.781 1.00 51.54  ? 104 GLU A O   1 
ATOM 761  C CB  . GLU A 1 105 ? 288.664 326.134 393.798 1.00 51.54  ? 104 GLU A CB  1 
ATOM 762  C CG  . GLU A 1 105 ? 287.964 327.458 394.035 1.00 51.54  ? 104 GLU A CG  1 
ATOM 763  C CD  . GLU A 1 105 ? 287.359 328.029 392.772 1.00 51.54  ? 104 GLU A CD  1 
ATOM 764  O OE1 . GLU A 1 105 ? 287.269 327.288 391.771 1.00 51.54  ? 104 GLU A OE1 1 
ATOM 765  O OE2 . GLU A 1 105 ? 286.974 329.216 392.781 1.00 51.54  ? 104 GLU A OE2 1 
ATOM 766  N N   . ARG A 1 106 ? 291.627 324.996 393.836 1.00 44.21  ? 105 ARG A N   1 
ATOM 767  C CA  . ARG A 1 106 ? 292.609 324.003 393.414 1.00 44.21  ? 105 ARG A CA  1 
ATOM 768  C C   . ARG A 1 106 ? 293.245 323.320 394.618 1.00 44.21  ? 105 ARG A C   1 
ATOM 769  O O   . ARG A 1 106 ? 293.382 322.087 394.653 1.00 44.21  ? 105 ARG A O   1 
ATOM 770  C CB  . ARG A 1 106 ? 293.671 324.669 392.542 1.00 44.21  ? 105 ARG A CB  1 
ATOM 771  C CG  . ARG A 1 106 ? 293.106 325.372 391.327 1.00 44.21  ? 105 ARG A CG  1 
ATOM 772  C CD  . ARG A 1 106 ? 294.169 325.592 390.269 1.00 44.21  ? 105 ARG A CD  1 
ATOM 773  N NE  . ARG A 1 106 ? 295.067 326.688 390.605 1.00 44.21  ? 105 ARG A NE  1 
ATOM 774  C CZ  . ARG A 1 106 ? 294.831 327.960 390.321 1.00 44.21  ? 105 ARG A CZ  1 
ATOM 775  N NH1 . ARG A 1 106 ? 293.731 328.333 389.690 1.00 44.21  ? 105 ARG A NH1 1 
ATOM 776  N NH2 . ARG A 1 106 ? 295.721 328.881 390.675 1.00 44.21  ? 105 ARG A NH2 1 
ATOM 777  N N   . ALA A 1 107 ? 293.626 324.107 395.626 1.00 45.82  ? 106 ALA A N   1 
ATOM 778  C CA  . ALA A 1 107 ? 294.202 323.524 396.832 1.00 45.82  ? 106 ALA A CA  1 
ATOM 779  C C   . ALA A 1 107 ? 293.205 322.616 397.533 1.00 45.82  ? 106 ALA A C   1 
ATOM 780  O O   . ALA A 1 107 ? 293.570 321.544 398.027 1.00 45.82  ? 106 ALA A O   1 
ATOM 781  C CB  . ALA A 1 107 ? 294.679 324.626 397.774 1.00 45.82  ? 106 ALA A CB  1 
ATOM 782  N N   . PHE A 1 108 ? 291.938 323.030 397.587 1.00 46.71  ? 107 PHE A N   1 
ATOM 783  C CA  . PHE A 1 108 ? 290.924 322.218 398.242 1.00 46.71  ? 107 PHE A CA  1 
ATOM 784  C C   . PHE A 1 108 ? 290.749 320.884 397.536 1.00 46.71  ? 107 PHE A C   1 
ATOM 785  O O   . PHE A 1 108 ? 290.658 319.841 398.188 1.00 46.71  ? 107 PHE A O   1 
ATOM 786  C CB  . PHE A 1 108 ? 289.600 322.975 398.294 1.00 46.71  ? 107 PHE A CB  1 
ATOM 787  C CG  . PHE A 1 108 ? 288.559 322.316 399.145 1.00 46.71  ? 107 PHE A CG  1 
ATOM 788  C CD1 . PHE A 1 108 ? 287.717 321.356 398.615 1.00 46.71  ? 107 PHE A CD1 1 
ATOM 789  C CD2 . PHE A 1 108 ? 288.422 322.655 400.477 1.00 46.71  ? 107 PHE A CD2 1 
ATOM 790  C CE1 . PHE A 1 108 ? 286.764 320.750 399.397 1.00 46.71  ? 107 PHE A CE1 1 
ATOM 791  C CE2 . PHE A 1 108 ? 287.469 322.051 401.262 1.00 46.71  ? 107 PHE A CE2 1 
ATOM 792  C CZ  . PHE A 1 108 ? 286.639 321.097 400.721 1.00 46.71  ? 107 PHE A CZ  1 
ATOM 793  N N   . VAL A 1 109 ? 290.698 320.892 396.203 1.00 43.15  ? 108 VAL A N   1 
ATOM 794  C CA  . VAL A 1 109 ? 290.521 319.640 395.471 1.00 43.15  ? 108 VAL A CA  1 
ATOM 795  C C   . VAL A 1 109 ? 291.718 318.724 395.681 1.00 43.15  ? 108 VAL A C   1 
ATOM 796  O O   . VAL A 1 109 ? 291.562 317.516 395.911 1.00 43.15  ? 108 VAL A O   1 
ATOM 797  C CB  . VAL A 1 109 ? 290.275 319.914 393.977 1.00 43.15  ? 108 VAL A CB  1 
ATOM 798  C CG1 . VAL A 1 109 ? 290.206 318.613 393.213 1.00 43.15  ? 108 VAL A CG1 1 
ATOM 799  C CG2 . VAL A 1 109 ? 288.992 320.691 393.794 1.00 43.15  ? 108 VAL A CG2 1 
ATOM 800  N N   . ARG A 1 110 ? 292.931 319.279 395.613 1.00 41.50  ? 109 ARG A N   1 
ATOM 801  C CA  . ARG A 1 110 ? 294.124 318.458 395.805 1.00 41.50  ? 109 ARG A CA  1 
ATOM 802  C C   . ARG A 1 110 ? 294.148 317.840 397.198 1.00 41.50  ? 109 ARG A C   1 
ATOM 803  O O   . ARG A 1 110 ? 294.414 316.641 397.359 1.00 41.50  ? 109 ARG A O   1 
ATOM 804  C CB  . ARG A 1 110 ? 295.376 319.299 395.565 1.00 41.50  ? 109 ARG A CB  1 
ATOM 805  C CG  . ARG A 1 110 ? 296.672 318.612 395.934 1.00 41.50  ? 109 ARG A CG  1 
ATOM 806  C CD  . ARG A 1 110 ? 297.854 319.546 395.761 1.00 41.50  ? 109 ARG A CD  1 
ATOM 807  N NE  . ARG A 1 110 ? 297.801 320.672 396.683 1.00 41.50  ? 109 ARG A NE  1 
ATOM 808  C CZ  . ARG A 1 110 ? 298.183 320.621 397.951 1.00 41.50  ? 109 ARG A CZ  1 
ATOM 809  N NH1 . ARG A 1 110 ? 298.668 319.511 398.481 1.00 41.50  ? 109 ARG A NH1 1 
ATOM 810  N NH2 . ARG A 1 110 ? 298.073 321.709 398.705 1.00 41.50  ? 109 ARG A NH2 1 
ATOM 811  N N   . THR A 1 111 ? 293.847 318.640 398.222 1.00 45.08  ? 110 THR A N   1 
ATOM 812  C CA  . THR A 1 111 ? 293.890 318.135 399.588 1.00 45.08  ? 110 THR A CA  1 
ATOM 813  C C   . THR A 1 111 ? 292.780 317.124 399.843 1.00 45.08  ? 110 THR A C   1 
ATOM 814  O O   . THR A 1 111 ? 292.985 316.137 400.558 1.00 45.08  ? 110 THR A O   1 
ATOM 815  C CB  . THR A 1 111 ? 293.800 319.295 400.573 1.00 45.08  ? 110 THR A CB  1 
ATOM 816  O OG1 . THR A 1 111 ? 294.831 320.243 400.280 1.00 45.08  ? 110 THR A OG1 1 
ATOM 817  C CG2 . THR A 1 111 ? 293.995 318.795 401.982 1.00 45.08  ? 110 THR A CG2 1 
ATOM 818  N N   . GLU A 1 112 ? 291.598 317.351 399.268 1.00 44.87  ? 111 GLU A N   1 
ATOM 819  C CA  . GLU A 1 112 ? 290.510 316.389 399.387 1.00 44.87  ? 111 GLU A CA  1 
ATOM 820  C C   . GLU A 1 112 ? 290.886 315.050 398.774 1.00 44.87  ? 111 GLU A C   1 
ATOM 821  O O   . GLU A 1 112 ? 290.622 313.994 399.360 1.00 44.87  ? 111 GLU A O   1 
ATOM 822  C CB  . GLU A 1 112 ? 289.259 316.945 398.713 1.00 44.87  ? 111 GLU A CB  1 
ATOM 823  C CG  . GLU A 1 112 ? 288.003 316.154 398.973 1.00 44.87  ? 111 GLU A CG  1 
ATOM 824  C CD  . GLU A 1 112 ? 286.834 316.671 398.169 1.00 44.87  ? 111 GLU A CD  1 
ATOM 825  O OE1 . GLU A 1 112 ? 285.753 316.883 398.749 1.00 44.87  ? 111 GLU A OE1 1 
ATOM 826  O OE2 . GLU A 1 112 ? 287.000 316.882 396.953 1.00 44.87  ? 111 GLU A OE2 1 
ATOM 827  N N   . LEU A 1 113 ? 291.490 315.072 397.585 1.00 40.92  ? 112 LEU A N   1 
ATOM 828  C CA  . LEU A 1 113 ? 291.909 313.820 396.968 1.00 40.92  ? 112 LEU A CA  1 
ATOM 829  C C   . LEU A 1 113 ? 292.974 313.127 397.806 1.00 40.92  ? 112 LEU A C   1 
ATOM 830  O O   . LEU A 1 113 ? 292.948 311.902 397.961 1.00 40.92  ? 112 LEU A O   1 
ATOM 831  C CB  . LEU A 1 113 ? 292.417 314.069 395.552 1.00 40.92  ? 112 LEU A CB  1 
ATOM 832  C CG  . LEU A 1 113 ? 292.772 312.802 394.777 1.00 40.92  ? 112 LEU A CG  1 
ATOM 833  C CD1 . LEU A 1 113 ? 291.671 311.770 394.908 1.00 40.92  ? 112 LEU A CD1 1 
ATOM 834  C CD2 . LEU A 1 113 ? 293.027 313.128 393.325 1.00 40.92  ? 112 LEU A CD2 1 
ATOM 835  N N   . ALA A 1 114 ? 293.918 313.894 398.356 1.00 41.00  ? 113 ALA A N   1 
ATOM 836  C CA  . ALA A 1 114 ? 294.950 313.290 399.193 1.00 41.00  ? 113 ALA A CA  1 
ATOM 837  C C   . ALA A 1 114 ? 294.353 312.660 400.446 1.00 41.00  ? 113 ALA A C   1 
ATOM 838  O O   . ALA A 1 114 ? 294.808 311.603 400.895 1.00 41.00  ? 113 ALA A O   1 
ATOM 839  C CB  . ALA A 1 114 ? 296.001 314.332 399.566 1.00 41.00  ? 113 ALA A CB  1 
ATOM 840  N N   . ALA A 1 115 ? 293.339 313.300 401.030 1.00 41.07  ? 114 ALA A N   1 
ATOM 841  C CA  . ALA A 1 115 ? 292.744 312.803 402.266 1.00 41.07  ? 114 ALA A CA  1 
ATOM 842  C C   . ALA A 1 115 ? 291.815 311.618 402.039 1.00 41.07  ? 114 ALA A C   1 
ATOM 843  O O   . ALA A 1 115 ? 291.680 310.772 402.928 1.00 41.07  ? 114 ALA A O   1 
ATOM 844  C CB  . ALA A 1 115 ? 291.985 313.925 402.972 1.00 41.07  ? 114 ALA A CB  1 
ATOM 845  N N   . LEU A 1 116 ? 291.153 311.546 400.881 1.00 42.66  ? 115 LEU A N   1 
ATOM 846  C CA  . LEU A 1 116 ? 290.261 310.418 400.616 1.00 42.66  ? 115 LEU A CA  1 
ATOM 847  C C   . LEU A 1 116 ? 291.022 309.102 400.563 1.00 42.66  ? 115 LEU A C   1 
ATOM 848  O O   . LEU A 1 116 ? 290.542 308.081 401.066 1.00 42.66  ? 115 LEU A O   1 
ATOM 849  C CB  . LEU A 1 116 ? 289.501 310.631 399.310 1.00 42.66  ? 115 LEU A CB  1 
ATOM 850  C CG  . LEU A 1 116 ? 288.242 311.489 399.365 1.00 42.66  ? 115 LEU A CG  1 
ATOM 851  C CD1 . LEU A 1 116 ? 287.706 311.703 397.966 1.00 42.66  ? 115 LEU A CD1 1 
ATOM 852  C CD2 . LEU A 1 116 ? 287.198 310.825 400.237 1.00 42.66  ? 115 LEU A CD2 1 
ATOM 853  N N   . LEU A 1 117 ? 292.207 309.101 399.952 1.00 40.61  ? 116 LEU A N   1 
ATOM 854  C CA  . LEU A 1 117 ? 292.956 307.863 399.783 1.00 40.61  ? 116 LEU A CA  1 
ATOM 855  C C   . LEU A 1 117 ? 293.372 307.246 401.111 1.00 40.61  ? 116 LEU A C   1 
ATOM 856  O O   . LEU A 1 117 ? 293.733 306.066 401.144 1.00 40.61  ? 116 LEU A O   1 
ATOM 857  C CB  . LEU A 1 117 ? 294.184 308.114 398.913 1.00 40.61  ? 116 LEU A CB  1 
ATOM 858  C CG  . LEU A 1 117 ? 293.890 308.533 397.474 1.00 40.61  ? 116 LEU A CG  1 
ATOM 859  C CD1 . LEU A 1 117 ? 295.133 309.094 396.825 1.00 40.61  ? 116 LEU A CD1 1 
ATOM 860  C CD2 . LEU A 1 117 ? 293.357 307.362 396.675 1.00 40.61  ? 116 LEU A CD2 1 
ATOM 861  N N   . ALA A 1 118 ? 293.342 308.010 402.199 1.00 42.30  ? 117 ALA A N   1 
ATOM 862  C CA  . ALA A 1 118 ? 293.610 307.465 403.521 1.00 42.30  ? 117 ALA A CA  1 
ATOM 863  C C   . ALA A 1 118 ? 292.348 307.051 404.264 1.00 42.30  ? 117 ALA A C   1 
ATOM 864  O O   . ALA A 1 118 ? 292.451 306.464 405.346 1.00 42.30  ? 117 ALA A O   1 
ATOM 865  C CB  . ALA A 1 118 ? 294.384 308.483 404.364 1.00 42.30  ? 117 ALA A CB  1 
ATOM 866  N N   . SER A 1 119 ? 291.169 307.339 403.720 1.00 44.69  ? 118 SER A N   1 
ATOM 867  C CA  . SER A 1 119 ? 289.930 306.974 404.384 1.00 44.69  ? 118 SER A CA  1 
ATOM 868  C C   . SER A 1 119 ? 289.716 305.462 404.323 1.00 44.69  ? 118 SER A C   1 
ATOM 869  O O   . SER A 1 119 ? 290.194 304.800 403.400 1.00 44.69  ? 118 SER A O   1 
ATOM 870  C CB  . SER A 1 119 ? 288.749 307.689 403.737 1.00 44.69  ? 118 SER A CB  1 
ATOM 871  O OG  . SER A 1 119 ? 288.269 306.964 402.621 1.00 44.69  ? 118 SER A OG  1 
ATOM 872  N N   . PRO A 1 120 ? 288.999 304.894 405.297 1.00 47.49  ? 119 PRO A N   1 
ATOM 873  C CA  . PRO A 1 120 ? 288.787 303.437 405.296 1.00 47.49  ? 119 PRO A CA  1 
ATOM 874  C C   . PRO A 1 120 ? 288.083 302.918 404.057 1.00 47.49  ? 119 PRO A C   1 
ATOM 875  O O   . PRO A 1 120 ? 288.333 301.777 403.649 1.00 47.49  ? 119 PRO A O   1 
ATOM 876  C CB  . PRO A 1 120 ? 287.943 303.212 406.557 1.00 47.49  ? 119 PRO A CB  1 
ATOM 877  C CG  . PRO A 1 120 ? 288.260 304.373 407.429 1.00 47.49  ? 119 PRO A CG  1 
ATOM 878  C CD  . PRO A 1 120 ? 288.434 305.527 406.499 1.00 47.49  ? 119 PRO A CD  1 
ATOM 879  N N   . LEU A 1 121 ? 287.208 303.719 403.447 1.00 46.64  ? 120 LEU A N   1 
ATOM 880  C CA  . LEU A 1 121 ? 286.497 303.273 402.254 1.00 46.64  ? 120 LEU A CA  1 
ATOM 881  C C   . LEU A 1 121 ? 287.464 302.949 401.122 1.00 46.64  ? 120 LEU A C   1 
ATOM 882  O O   . LEU A 1 121 ? 287.421 301.857 400.546 1.00 46.64  ? 120 LEU A O   1 
ATOM 883  C CB  . LEU A 1 121 ? 285.497 304.343 401.819 1.00 46.64  ? 120 LEU A CB  1 
ATOM 884  C CG  . LEU A 1 121 ? 284.853 304.160 400.448 1.00 46.64  ? 120 LEU A CG  1 
ATOM 885  C CD1 . LEU A 1 121 ? 283.670 303.222 400.543 1.00 46.64  ? 120 LEU A CD1 1 
ATOM 886  C CD2 . LEU A 1 121 ? 284.425 305.503 399.887 1.00 46.64  ? 120 LEU A CD2 1 
ATOM 887  N N   . LEU A 1 122 ? 288.361 303.883 400.803 1.00 44.29  ? 121 LEU A N   1 
ATOM 888  C CA  . LEU A 1 122 ? 289.321 303.646 399.731 1.00 44.29  ? 121 LEU A CA  1 
ATOM 889  C C   . LEU A 1 122 ? 290.342 302.585 400.114 1.00 44.29  ? 121 LEU A C   1 
ATOM 890  O O   . LEU A 1 122 ? 290.779 301.807 399.257 1.00 44.29  ? 121 LEU A O   1 
ATOM 891  C CB  . LEU A 1 122 ? 290.022 304.949 399.358 1.00 44.29  ? 121 LEU A CB  1 
ATOM 892  C CG  . LEU A 1 122 ? 289.422 305.753 398.205 1.00 44.29  ? 121 LEU A CG  1 
ATOM 893  C CD1 . LEU A 1 122 ? 289.523 304.971 396.915 1.00 44.29  ? 121 LEU A CD1 1 
ATOM 894  C CD2 . LEU A 1 122 ? 287.981 306.128 398.485 1.00 44.29  ? 121 LEU A CD2 1 
ATOM 895  N N   . ILE A 1 123 ? 290.732 302.536 401.389 1.00 45.83  ? 122 ILE A N   1 
ATOM 896  C CA  . ILE A 1 123 ? 291.656 301.504 401.846 1.00 45.83  ? 122 ILE A CA  1 
ATOM 897  C C   . ILE A 1 123 ? 291.071 300.123 401.600 1.00 45.83  ? 122 ILE A C   1 
ATOM 898  O O   . ILE A 1 123 ? 291.755 299.219 401.110 1.00 45.83  ? 122 ILE A O   1 
ATOM 899  C CB  . ILE A 1 123 ? 291.998 301.710 403.333 1.00 45.83  ? 122 ILE A CB  1 
ATOM 900  C CG1 . ILE A 1 123 ? 292.796 302.995 403.530 1.00 45.83  ? 122 ILE A CG1 1 
ATOM 901  C CG2 . ILE A 1 123 ? 292.760 300.521 403.874 1.00 45.83  ? 122 ILE A CG2 1 
ATOM 902  C CD1 . ILE A 1 123 ? 293.228 303.219 404.958 1.00 45.83  ? 122 ILE A CD1 1 
ATOM 903  N N   . ASP A 1 124 ? 289.796 299.937 401.930 1.00 50.28  ? 123 ASP A N   1 
ATOM 904  C CA  . ASP A 1 124 ? 289.170 298.638 401.749 1.00 50.28  ? 123 ASP A CA  1 
ATOM 905  C C   . ASP A 1 124 ? 288.744 298.389 400.309 1.00 50.28  ? 123 ASP A C   1 
ATOM 906  O O   . ASP A 1 124 ? 288.520 297.235 399.940 1.00 50.28  ? 123 ASP A O   1 
ATOM 907  C CB  . ASP A 1 124 ? 287.961 298.509 402.677 1.00 50.28  ? 123 ASP A CB  1 
ATOM 908  C CG  . ASP A 1 124 ? 287.291 297.156 402.576 1.00 50.28  ? 123 ASP A CG  1 
ATOM 909  O OD1 . ASP A 1 124 ? 288.011 296.138 402.509 1.00 50.28  ? 123 ASP A OD1 1 
ATOM 910  O OD2 . ASP A 1 124 ? 286.045 297.107 402.556 1.00 50.28  ? 123 ASP A OD2 1 
ATOM 911  N N   . ALA A 1 125 ? 288.635 299.431 399.488 1.00 44.79  ? 124 ALA A N   1 
ATOM 912  C CA  . ALA A 1 125 ? 288.201 299.263 398.109 1.00 44.79  ? 124 ALA A CA  1 
ATOM 913  C C   . ALA A 1 125 ? 289.342 299.202 397.103 1.00 44.79  ? 124 ALA A C   1 
ATOM 914  O O   . ALA A 1 125 ? 289.084 298.923 395.929 1.00 44.79  ? 124 ALA A O   1 
ATOM 915  C CB  . ALA A 1 125 ? 287.248 300.396 397.713 1.00 44.79  ? 124 ALA A CB  1 
ATOM 916  N N   . ILE A 1 126 ? 290.580 299.467 397.509 1.00 44.09  ? 125 ILE A N   1 
ATOM 917  C CA  . ILE A 1 126 ? 291.735 299.364 396.625 1.00 44.09  ? 125 ILE A CA  1 
ATOM 918  C C   . ILE A 1 126 ? 292.637 298.199 397.017 1.00 44.09  ? 125 ILE A C   1 
ATOM 919  O O   . ILE A 1 126 ? 293.016 297.390 396.171 1.00 44.09  ? 125 ILE A O   1 
ATOM 920  C CB  . ILE A 1 126 ? 292.530 300.688 396.580 1.00 44.09  ? 125 ILE A CB  1 
ATOM 921  C CG1 . ILE A 1 126 ? 291.714 301.774 395.886 1.00 44.09  ? 125 ILE A CG1 1 
ATOM 922  C CG2 . ILE A 1 126 ? 293.839 300.495 395.842 1.00 44.09  ? 125 ILE A CG2 1 
ATOM 923  C CD1 . ILE A 1 126 ? 292.413 303.104 395.831 1.00 44.09  ? 125 ILE A CD1 1 
ATOM 924  N N   . ASP A 1 127 ? 293.001 298.106 398.297 1.00 49.07  ? 126 ASP A N   1 
ATOM 925  C CA  . ASP A 1 127 ? 293.809 296.978 398.750 1.00 49.07  ? 126 ASP A CA  1 
ATOM 926  C C   . ASP A 1 127 ? 293.083 295.661 398.513 1.00 49.07  ? 126 ASP A C   1 
ATOM 927  O O   . ASP A 1 127 ? 293.635 294.732 397.913 1.00 49.07  ? 126 ASP A O   1 
ATOM 928  C CB  . ASP A 1 127 ? 294.162 297.143 400.227 1.00 49.07  ? 126 ASP A CB  1 
ATOM 929  C CG  . ASP A 1 127 ? 294.857 298.455 400.514 1.00 49.07  ? 126 ASP A CG  1 
ATOM 930  O OD1 . ASP A 1 127 ? 295.072 299.233 399.564 1.00 49.07  ? 126 ASP A OD1 1 
ATOM 931  O OD2 . ASP A 1 127 ? 295.189 298.709 401.690 1.00 49.07  ? 126 ASP A OD2 1 
ATOM 932  N N   . GLN A 1 128 ? 291.843 295.565 398.977 1.00 50.41  ? 127 GLN A N   1 
ATOM 933  C CA  . GLN A 1 128 ? 290.946 294.482 398.605 1.00 50.41  ? 127 GLN A CA  1 
ATOM 934  C C   . GLN A 1 128 ? 289.991 295.010 397.548 1.00 50.41  ? 127 GLN A C   1 
ATOM 935  O O   . GLN A 1 128 ? 289.430 296.097 397.700 1.00 50.41  ? 127 GLN A O   1 
ATOM 936  C CB  . GLN A 1 128 ? 290.170 293.958 399.811 1.00 50.41  ? 127 GLN A CB  1 
ATOM 937  C CG  . GLN A 1 128 ? 290.968 293.033 400.710 1.00 50.41  ? 127 GLN A CG  1 
ATOM 938  C CD  . GLN A 1 128 ? 292.004 293.769 401.529 1.00 50.41  ? 127 GLN A CD  1 
ATOM 939  O OE1 . GLN A 1 128 ? 293.201 293.513 401.410 1.00 50.41  ? 127 GLN A OE1 1 
ATOM 940  N NE2 . GLN A 1 128 ? 291.547 294.690 402.368 1.00 50.41  ? 127 GLN A NE2 1 
ATOM 941  N N   . LEU A 1 129 ? 289.816 294.252 396.474 1.00 44.80  ? 128 LEU A N   1 
ATOM 942  C CA  . LEU A 1 129 ? 289.072 294.744 395.319 1.00 44.80  ? 128 LEU A CA  1 
ATOM 943  C C   . LEU A 1 129 ? 287.575 294.484 395.486 1.00 44.80  ? 128 LEU A C   1 
ATOM 944  O O   . LEU A 1 129 ? 286.943 293.784 394.697 1.00 44.80  ? 128 LEU A O   1 
ATOM 945  C CB  . LEU A 1 129 ? 289.610 294.105 394.047 1.00 44.80  ? 128 LEU A CB  1 
ATOM 946  C CG  . LEU A 1 129 ? 291.052 294.491 393.736 1.00 44.80  ? 128 LEU A CG  1 
ATOM 947  C CD1 . LEU A 1 129 ? 291.652 293.565 392.702 1.00 44.80  ? 128 LEU A CD1 1 
ATOM 948  C CD2 . LEU A 1 129 ? 291.100 295.927 393.256 1.00 44.80  ? 128 LEU A CD2 1 
ATOM 949  N N   . ASN A 1 130 ? 287.006 295.071 396.536 1.00 46.12  ? 129 ASN A N   1 
ATOM 950  C CA  . ASN A 1 130 ? 285.587 294.915 396.791 1.00 46.12  ? 129 ASN A CA  1 
ATOM 951  C C   . ASN A 1 130 ? 284.898 296.265 396.955 1.00 46.12  ? 129 ASN A C   1 
ATOM 952  O O   . ASN A 1 130 ? 285.448 297.169 397.596 1.00 46.12  ? 129 ASN A O   1 
ATOM 953  C CB  . ASN A 1 130 ? 285.332 293.997 398.022 1.00 46.12  ? 129 ASN A CB  1 
ATOM 954  C CG  . ASN A 1 130 ? 285.874 294.554 399.327 1.00 46.12  ? 129 ASN A CG  1 
ATOM 955  O OD1 . ASN A 1 130 ? 286.349 295.677 399.404 1.00 46.12  ? 129 ASN A OD1 1 
ATOM 956  N ND2 . ASN A 1 130 ? 285.800 293.743 400.371 1.00 46.12  ? 129 ASN A ND2 1 
ATOM 957  N N   . PRO A 1 131 ? 283.733 296.458 396.349 1.00 46.92  ? 130 PRO A N   1 
ATOM 958  C CA  . PRO A 1 131 ? 283.074 297.762 396.398 1.00 46.92  ? 130 PRO A CA  1 
ATOM 959  C C   . PRO A 1 131 ? 282.305 297.969 397.693 1.00 46.92  ? 130 PRO A C   1 
ATOM 960  O O   . PRO A 1 131 ? 282.121 297.058 398.500 1.00 46.92  ? 130 PRO A O   1 
ATOM 961  C CB  . PRO A 1 131 ? 282.121 297.711 395.202 1.00 46.92  ? 130 PRO A CB  1 
ATOM 962  C CG  . PRO A 1 131 ? 281.776 296.278 395.098 1.00 46.92  ? 130 PRO A CG  1 
ATOM 963  C CD  . PRO A 1 131 ? 283.028 295.526 395.454 1.00 46.92  ? 130 PRO A CD  1 
ATOM 964  N N   . ALA A 1 132 ? 281.854 299.206 397.874 1.00 53.14  ? 131 ALA A N   1 
ATOM 965  C CA  . ALA A 1 132 ? 281.052 299.550 399.037 1.00 53.14  ? 131 ALA A CA  1 
ATOM 966  C C   . ALA A 1 132 ? 279.619 299.066 398.866 1.00 53.14  ? 131 ALA A C   1 
ATOM 967  O O   . ALA A 1 132 ? 279.071 299.068 397.761 1.00 53.14  ? 131 ALA A O   1 
ATOM 968  C CB  . ALA A 1 132 ? 281.068 301.058 399.263 1.00 53.14  ? 131 ALA A CB  1 
ATOM 969  N N   . TYR A 1 133 ? 279.011 298.652 399.973 1.00 56.98  ? 132 TYR A N   1 
ATOM 970  C CA  . TYR A 1 133 ? 277.619 298.221 399.971 1.00 56.98  ? 132 TYR A CA  1 
ATOM 971  C C   . TYR A 1 133 ? 276.844 298.900 401.096 1.00 56.98  ? 132 TYR A C   1 
ATOM 972  O O   . TYR A 1 133 ? 276.093 299.846 400.864 1.00 56.98  ? 132 TYR A O   1 
ATOM 973  C CB  . TYR A 1 133 ? 277.524 296.700 400.104 1.00 56.98  ? 132 TYR A CB  1 
ATOM 974  C CG  . TYR A 1 133 ? 278.137 296.148 401.371 1.00 56.98  ? 132 TYR A CG  1 
ATOM 975  C CD1 . TYR A 1 133 ? 277.408 296.078 402.549 1.00 56.98  ? 132 TYR A CD1 1 
ATOM 976  C CD2 . TYR A 1 133 ? 279.442 295.684 401.385 1.00 56.98  ? 132 TYR A CD2 1 
ATOM 977  C CE1 . TYR A 1 133 ? 277.965 295.572 403.704 1.00 56.98  ? 132 TYR A CE1 1 
ATOM 978  C CE2 . TYR A 1 133 ? 280.006 295.177 402.535 1.00 56.98  ? 132 TYR A CE2 1 
ATOM 979  C CZ  . TYR A 1 133 ? 279.264 295.124 403.691 1.00 56.98  ? 132 TYR A CZ  1 
ATOM 980  O OH  . TYR A 1 133 ? 279.825 294.618 404.838 1.00 56.98  ? 132 TYR A OH  1 
ATOM 981  N N   . ALA B 1 2   ? 283.561 297.877 401.728 1.00 58.97  ? 1   ALA B N   1 
ATOM 982  C CA  . ALA B 1 2   ? 283.043 298.095 403.072 1.00 58.97  ? 1   ALA B CA  1 
ATOM 983  C C   . ALA B 1 2   ? 281.581 298.510 403.027 1.00 58.97  ? 1   ALA B C   1 
ATOM 984  O O   . ALA B 1 2   ? 280.907 298.331 402.019 1.00 58.97  ? 1   ALA B O   1 
ATOM 985  C CB  . ALA B 1 2   ? 283.868 299.145 403.794 1.00 58.97  ? 1   ALA B CB  1 
ATOM 986  N N   . LYS B 1 3   ? 281.098 299.071 404.130 1.00 59.20  ? 2   LYS B N   1 
ATOM 987  C CA  . LYS B 1 3   ? 279.728 299.543 404.240 1.00 59.20  ? 2   LYS B CA  1 
ATOM 988  C C   . LYS B 1 3   ? 279.711 301.062 404.161 1.00 59.20  ? 2   LYS B C   1 
ATOM 989  O O   . LYS B 1 3   ? 280.476 301.735 404.857 1.00 59.20  ? 2   LYS B O   1 
ATOM 990  C CB  . LYS B 1 3   ? 279.094 299.079 405.551 1.00 59.20  ? 2   LYS B CB  1 
ATOM 991  C CG  . LYS B 1 3   ? 277.712 299.642 405.807 1.00 59.20  ? 2   LYS B CG  1 
ATOM 992  C CD  . LYS B 1 3   ? 276.639 298.707 405.282 1.00 59.20  ? 2   LYS B CD  1 
ATOM 993  C CE  . LYS B 1 3   ? 275.278 299.374 405.285 1.00 59.20  ? 2   LYS B CE  1 
ATOM 994  N NZ  . LYS B 1 3   ? 274.469 298.980 404.101 1.00 59.20  ? 2   LYS B NZ  1 
ATOM 995  N N   . LEU B 1 4   ? 278.845 301.597 403.303 1.00 55.89  ? 3   LEU B N   1 
ATOM 996  C CA  . LEU B 1 4   ? 278.744 303.042 403.154 1.00 55.89  ? 3   LEU B CA  1 
ATOM 997  C C   . LEU B 1 4   ? 278.327 303.691 404.466 1.00 55.89  ? 3   LEU B C   1 
ATOM 998  O O   . LEU B 1 4   ? 277.382 303.247 405.125 1.00 55.89  ? 3   LEU B O   1 
ATOM 999  C CB  . LEU B 1 4   ? 277.746 303.398 402.054 1.00 55.89  ? 3   LEU B CB  1 
ATOM 1000 C CG  . LEU B 1 4   ? 278.304 303.554 400.642 1.00 55.89  ? 3   LEU B CG  1 
ATOM 1001 C CD1 . LEU B 1 4   ? 277.189 303.875 399.672 1.00 55.89  ? 3   LEU B CD1 1 
ATOM 1002 C CD2 . LEU B 1 4   ? 279.355 304.643 400.619 1.00 55.89  ? 3   LEU B CD2 1 
ATOM 1003 N N   . GLU B 1 5   ? 279.034 304.752 404.837 1.00 58.08  ? 4   GLU B N   1 
ATOM 1004 C CA  . GLU B 1 5   ? 278.734 305.505 406.043 1.00 58.08  ? 4   GLU B CA  1 
ATOM 1005 C C   . GLU B 1 5   ? 279.257 306.919 405.855 1.00 58.08  ? 4   GLU B C   1 
ATOM 1006 O O   . GLU B 1 5   ? 279.950 307.220 404.881 1.00 58.08  ? 4   GLU B O   1 
ATOM 1007 C CB  . GLU B 1 5   ? 279.346 304.848 407.282 1.00 58.08  ? 4   GLU B CB  1 
ATOM 1008 C CG  . GLU B 1 5   ? 280.845 304.644 407.189 1.00 58.08  ? 4   GLU B CG  1 
ATOM 1009 C CD  . GLU B 1 5   ? 281.328 303.474 408.022 1.00 58.08  ? 4   GLU B CD  1 
ATOM 1010 O OE1 . GLU B 1 5   ? 280.490 302.830 408.687 1.00 58.08  ? 4   GLU B OE1 1 
ATOM 1011 O OE2 . GLU B 1 5   ? 282.546 303.198 408.012 1.00 58.08  ? 4   GLU B OE2 1 
ATOM 1012 N N   . THR B 1 6   ? 278.907 307.794 406.793 1.00 55.17  ? 5   THR B N   1 
ATOM 1013 C CA  . THR B 1 6   ? 279.365 309.174 406.723 1.00 55.17  ? 5   THR B CA  1 
ATOM 1014 C C   . THR B 1 6   ? 280.885 309.224 406.748 1.00 55.17  ? 5   THR B C   1 
ATOM 1015 O O   . THR B 1 6   ? 281.526 308.605 407.601 1.00 55.17  ? 5   THR B O   1 
ATOM 1016 C CB  . THR B 1 6   ? 278.796 309.986 407.883 1.00 55.17  ? 5   THR B CB  1 
ATOM 1017 O OG1 . THR B 1 6   ? 279.326 309.487 409.115 1.00 55.17  ? 5   THR B OG1 1 
ATOM 1018 C CG2 . THR B 1 6   ? 277.285 309.874 407.912 1.00 55.17  ? 5   THR B CG2 1 
ATOM 1019 N N   . VAL B 1 7   ? 281.460 309.968 405.809 1.00 53.41  ? 6   VAL B N   1 
ATOM 1020 C CA  . VAL B 1 7   ? 282.903 310.117 405.686 1.00 53.41  ? 6   VAL B CA  1 
ATOM 1021 C C   . VAL B 1 7   ? 283.254 311.548 406.055 1.00 53.41  ? 6   VAL B C   1 
ATOM 1022 O O   . VAL B 1 7   ? 282.749 312.496 405.442 1.00 53.41  ? 6   VAL B O   1 
ATOM 1023 C CB  . VAL B 1 7   ? 283.390 309.781 404.269 1.00 53.41  ? 6   VAL B CB  1 
ATOM 1024 C CG1 . VAL B 1 7   ? 284.867 310.083 404.136 1.00 53.41  ? 6   VAL B CG1 1 
ATOM 1025 C CG2 . VAL B 1 7   ? 283.113 308.326 403.947 1.00 53.41  ? 6   VAL B CG2 1 
ATOM 1026 N N   . THR B 1 8   ? 284.115 311.707 407.052 1.00 54.38  ? 7   THR B N   1 
ATOM 1027 C CA  . THR B 1 8   ? 284.582 313.016 407.480 1.00 54.38  ? 7   THR B CA  1 
ATOM 1028 C C   . THR B 1 8   ? 286.068 313.154 407.178 1.00 54.38  ? 7   THR B C   1 
ATOM 1029 O O   . THR B 1 8   ? 286.851 312.229 407.414 1.00 54.38  ? 7   THR B O   1 
ATOM 1030 C CB  . THR B 1 8   ? 284.309 313.243 408.971 1.00 54.38  ? 7   THR B CB  1 
ATOM 1031 O OG1 . THR B 1 8   ? 284.849 314.509 409.370 1.00 54.38  ? 7   THR B OG1 1 
ATOM 1032 C CG2 . THR B 1 8   ? 284.916 312.134 409.816 1.00 54.38  ? 7   THR B CG2 1 
ATOM 1033 N N   . LEU B 1 9   ? 286.446 314.305 406.634 1.00 53.90  ? 8   LEU B N   1 
ATOM 1034 C CA  . LEU B 1 9   ? 287.815 314.569 406.212 1.00 53.90  ? 8   LEU B CA  1 
ATOM 1035 C C   . LEU B 1 9   ? 288.334 315.773 406.981 1.00 53.90  ? 8   LEU B C   1 
ATOM 1036 O O   . LEU B 1 9   ? 287.754 316.859 406.900 1.00 53.90  ? 8   LEU B O   1 
ATOM 1037 C CB  . LEU B 1 9   ? 287.877 314.818 404.705 1.00 53.90  ? 8   LEU B CB  1 
ATOM 1038 C CG  . LEU B 1 9   ? 287.207 313.738 403.856 1.00 53.90  ? 8   LEU B CG  1 
ATOM 1039 C CD1 . LEU B 1 9   ? 287.113 314.163 402.405 1.00 53.90  ? 8   LEU B CD1 1 
ATOM 1040 C CD2 . LEU B 1 9   ? 287.956 312.426 403.984 1.00 53.90  ? 8   LEU B CD2 1 
ATOM 1041 N N   . GLY B 1 10  ? 289.422 315.581 407.719 1.00 57.07  ? 9   GLY B N   1 
ATOM 1042 C CA  . GLY B 1 10  ? 289.965 316.645 408.537 1.00 57.07  ? 9   GLY B CA  1 
ATOM 1043 C C   . GLY B 1 10  ? 291.264 317.210 408.005 1.00 57.07  ? 9   GLY B C   1 
ATOM 1044 O O   . GLY B 1 10  ? 291.939 316.570 407.194 1.00 57.07  ? 9   GLY B O   1 
ATOM 1045 N N   . ASN B 1 11  ? 291.621 318.411 408.463 1.00 59.91  ? 10  ASN B N   1 
ATOM 1046 C CA  . ASN B 1 11  ? 292.842 319.094 408.035 1.00 59.91  ? 10  ASN B CA  1 
ATOM 1047 C C   . ASN B 1 11  ? 292.880 319.260 406.518 1.00 59.91  ? 10  ASN B C   1 
ATOM 1048 O O   . ASN B 1 11  ? 293.927 319.129 405.883 1.00 59.91  ? 10  ASN B O   1 
ATOM 1049 C CB  . ASN B 1 11  ? 294.087 318.362 408.539 1.00 59.91  ? 10  ASN B CB  1 
ATOM 1050 C CG  . ASN B 1 11  ? 293.974 317.967 409.997 1.00 59.91  ? 10  ASN B CG  1 
ATOM 1051 O OD1 . ASN B 1 11  ? 293.201 318.556 410.753 1.00 59.91  ? 10  ASN B OD1 1 
ATOM 1052 N ND2 . ASN B 1 11  ? 294.745 316.965 410.402 1.00 59.91  ? 10  ASN B ND2 1 
ATOM 1053 N N   . ILE B 1 12  ? 291.726 319.549 405.940 1.00 57.33  ? 11  ILE B N   1 
ATOM 1054 C CA  . ILE B 1 12  ? 291.604 319.750 404.507 1.00 57.33  ? 11  ILE B CA  1 
ATOM 1055 C C   . ILE B 1 12  ? 291.814 321.229 404.201 1.00 57.33  ? 11  ILE B C   1 
ATOM 1056 O O   . ILE B 1 12  ? 291.745 322.087 405.083 1.00 57.33  ? 11  ILE B O   1 
ATOM 1057 C CB  . ILE B 1 12  ? 290.234 319.252 404.005 1.00 57.33  ? 11  ILE B CB  1 
ATOM 1058 C CG1 . ILE B 1 12  ? 290.280 318.887 402.529 1.00 57.33  ? 11  ILE B CG1 1 
ATOM 1059 C CG2 . ILE B 1 12  ? 289.169 320.296 404.215 1.00 57.33  ? 11  ILE B CG2 1 
ATOM 1060 C CD1 . ILE B 1 12  ? 289.007 318.242 402.066 1.00 57.33  ? 11  ILE B CD1 1 
ATOM 1061 N N   . GLY B 1 13  ? 292.091 321.532 402.939 1.00 56.78  ? 12  GLY B N   1 
ATOM 1062 C CA  . GLY B 1 13  ? 292.250 322.900 402.496 1.00 56.78  ? 12  GLY B CA  1 
ATOM 1063 C C   . GLY B 1 13  ? 293.706 323.327 402.444 1.00 56.78  ? 12  GLY B C   1 
ATOM 1064 O O   . GLY B 1 13  ? 294.621 322.612 402.858 1.00 56.78  ? 12  GLY B O   1 
ATOM 1065 N N   . LYS B 1 14  ? 293.914 324.530 401.906 1.00 59.32  ? 13  LYS B N   1 
ATOM 1066 C CA  . LYS B 1 14  ? 295.270 325.052 401.775 1.00 59.32  ? 13  LYS B CA  1 
ATOM 1067 C C   . LYS B 1 14  ? 295.887 325.322 403.139 1.00 59.32  ? 13  LYS B C   1 
ATOM 1068 O O   . LYS B 1 14  ? 297.009 324.886 403.423 1.00 59.32  ? 13  LYS B O   1 
ATOM 1069 C CB  . LYS B 1 14  ? 295.270 326.329 400.936 1.00 59.32  ? 13  LYS B CB  1 
ATOM 1070 C CG  . LYS B 1 14  ? 296.659 326.899 400.723 1.00 59.32  ? 13  LYS B CG  1 
ATOM 1071 C CD  . LYS B 1 14  ? 296.653 328.090 399.783 1.00 59.32  ? 13  LYS B CD  1 
ATOM 1072 C CE  . LYS B 1 14  ? 296.066 329.316 400.458 1.00 59.32  ? 13  LYS B CE  1 
ATOM 1073 N NZ  . LYS B 1 14  ? 296.155 330.529 399.600 1.00 59.32  ? 13  LYS B NZ  1 
ATOM 1074 N N   . ASP B 1 15  ? 295.165 326.041 404.001 1.00 64.77  ? 14  ASP B N   1 
ATOM 1075 C CA  . ASP B 1 15  ? 295.688 326.348 405.326 1.00 64.77  ? 14  ASP B CA  1 
ATOM 1076 C C   . ASP B 1 15  ? 295.736 325.112 406.214 1.00 64.77  ? 14  ASP B C   1 
ATOM 1077 O O   . ASP B 1 15  ? 296.543 325.054 407.148 1.00 64.77  ? 14  ASP B O   1 
ATOM 1078 C CB  . ASP B 1 15  ? 294.850 327.449 405.975 1.00 64.77  ? 14  ASP B CB  1 
ATOM 1079 C CG  . ASP B 1 15  ? 293.369 327.130 405.978 1.00 64.77  ? 14  ASP B CG  1 
ATOM 1080 O OD1 . ASP B 1 15  ? 292.636 327.701 406.812 1.00 64.77  ? 14  ASP B OD1 1 
ATOM 1081 O OD2 . ASP B 1 15  ? 292.935 326.314 405.140 1.00 64.77  ? 14  ASP B OD2 1 
ATOM 1082 N N   . GLY B 1 16  ? 294.897 324.121 405.943 1.00 61.58  ? 15  GLY B N   1 
ATOM 1083 C CA  . GLY B 1 16  ? 294.897 322.892 406.704 1.00 61.58  ? 15  GLY B CA  1 
ATOM 1084 C C   . GLY B 1 16  ? 293.989 322.861 407.912 1.00 61.58  ? 15  GLY B C   1 
ATOM 1085 O O   . GLY B 1 16  ? 294.183 322.004 408.781 1.00 61.58  ? 15  GLY B O   1 
ATOM 1086 N N   . LYS B 1 17  ? 293.010 323.761 408.000 1.00 65.04  ? 16  LYS B N   1 
ATOM 1087 C CA  . LYS B 1 17  ? 292.116 323.823 409.146 1.00 65.04  ? 16  LYS B CA  1 
ATOM 1088 C C   . LYS B 1 17  ? 290.667 323.504 408.813 1.00 65.04  ? 16  LYS B C   1 
ATOM 1089 O O   . LYS B 1 17  ? 289.843 323.433 409.730 1.00 65.04  ? 16  LYS B O   1 
ATOM 1090 C CB  . LYS B 1 17  ? 292.183 325.214 409.795 1.00 65.04  ? 16  LYS B CB  1 
ATOM 1091 C CG  . LYS B 1 17  ? 293.560 325.849 409.769 1.00 65.04  ? 16  LYS B CG  1 
ATOM 1092 C CD  . LYS B 1 17  ? 294.509 325.147 410.724 1.00 65.04  ? 16  LYS B CD  1 
ATOM 1093 C CE  . LYS B 1 17  ? 295.882 325.795 410.704 1.00 65.04  ? 16  LYS B CE  1 
ATOM 1094 N NZ  . LYS B 1 17  ? 295.790 327.281 410.657 1.00 65.04  ? 16  LYS B NZ  1 
ATOM 1095 N N   . GLN B 1 18  ? 290.329 323.316 407.541 1.00 61.87  ? 17  GLN B N   1 
ATOM 1096 C CA  . GLN B 1 18  ? 288.951 323.054 407.160 1.00 61.87  ? 17  GLN B CA  1 
ATOM 1097 C C   . GLN B 1 18  ? 288.611 321.576 407.330 1.00 61.87  ? 17  GLN B C   1 
ATOM 1098 O O   . GLN B 1 18  ? 289.486 320.719 407.461 1.00 61.87  ? 17  GLN B O   1 
ATOM 1099 C CB  . GLN B 1 18  ? 288.707 323.479 405.715 1.00 61.87  ? 17  GLN B CB  1 
ATOM 1100 C CG  . GLN B 1 18  ? 288.801 324.969 405.478 1.00 61.87  ? 17  GLN B CG  1 
ATOM 1101 C CD  . GLN B 1 18  ? 288.571 325.331 404.030 1.00 61.87  ? 17  GLN B CD  1 
ATOM 1102 O OE1 . GLN B 1 18  ? 288.403 324.457 403.181 1.00 61.87  ? 17  GLN B OE1 1 
ATOM 1103 N NE2 . GLN B 1 18  ? 288.562 326.625 403.736 1.00 61.87  ? 17  GLN B NE2 1 
ATOM 1104 N N   . THR B 1 19  ? 287.311 321.286 407.331 1.00 60.41  ? 18  THR B N   1 
ATOM 1105 C CA  . THR B 1 19  ? 286.812 319.919 407.392 1.00 60.41  ? 18  THR B CA  1 
ATOM 1106 C C   . THR B 1 19  ? 285.702 319.751 406.367 1.00 60.41  ? 18  THR B C   1 
ATOM 1107 O O   . THR B 1 19  ? 285.245 320.718 405.753 1.00 60.41  ? 18  THR B O   1 
ATOM 1108 C CB  . THR B 1 19  ? 286.282 319.546 408.785 1.00 60.41  ? 18  THR B CB  1 
ATOM 1109 O OG1 . THR B 1 19  ? 285.144 320.356 409.099 1.00 60.41  ? 18  THR B OG1 1 
ATOM 1110 C CG2 . THR B 1 19  ? 287.356 319.742 409.848 1.00 60.41  ? 18  THR B CG2 1 
ATOM 1111 N N   . LEU B 1 20  ? 285.270 318.506 406.185 1.00 54.24  ? 19  LEU B N   1 
ATOM 1112 C CA  . LEU B 1 20  ? 284.204 318.202 405.241 1.00 54.24  ? 19  LEU B CA  1 
ATOM 1113 C C   . LEU B 1 20  ? 283.580 316.865 405.606 1.00 54.24  ? 19  LEU B C   1 
ATOM 1114 O O   . LEU B 1 20  ? 284.300 315.894 405.854 1.00 54.24  ? 19  LEU B O   1 
ATOM 1115 C CB  . LEU B 1 20  ? 284.739 318.173 403.807 1.00 54.24  ? 19  LEU B CB  1 
ATOM 1116 C CG  . LEU B 1 20  ? 283.779 317.742 402.704 1.00 54.24  ? 19  LEU B CG  1 
ATOM 1117 C CD1 . LEU B 1 20  ? 282.483 318.513 402.798 1.00 54.24  ? 19  LEU B CD1 1 
ATOM 1118 C CD2 . LEU B 1 20  ? 284.417 317.966 401.358 1.00 54.24  ? 19  LEU B CD2 1 
ATOM 1119 N N   . VAL B 1 21  ? 282.250 316.815 405.635 1.00 52.06  ? 20  VAL B N   1 
ATOM 1120 C CA  . VAL B 1 21  ? 281.510 315.599 405.945 1.00 52.06  ? 20  VAL B CA  1 
ATOM 1121 C C   . VAL B 1 21  ? 280.651 315.228 404.745 1.00 52.06  ? 20  VAL B C   1 
ATOM 1122 O O   . VAL B 1 21  ? 279.986 316.084 404.153 1.00 52.06  ? 20  VAL B O   1 
ATOM 1123 C CB  . VAL B 1 21  ? 280.647 315.756 407.215 1.00 52.06  ? 20  VAL B CB  1 
ATOM 1124 C CG1 . VAL B 1 21  ? 281.534 315.902 408.434 1.00 52.06  ? 20  VAL B CG1 1 
ATOM 1125 C CG2 . VAL B 1 21  ? 279.730 316.955 407.095 1.00 52.06  ? 20  VAL B CG2 1 
ATOM 1126 N N   . LEU B 1 22  ? 280.684 313.951 404.377 1.00 49.77  ? 21  LEU B N   1 
ATOM 1127 C CA  . LEU B 1 22  ? 279.968 313.441 403.217 1.00 49.77  ? 21  LEU B CA  1 
ATOM 1128 C C   . LEU B 1 22  ? 278.959 312.398 403.672 1.00 49.77  ? 21  LEU B C   1 
ATOM 1129 O O   . LEU B 1 22  ? 279.298 311.499 404.445 1.00 49.77  ? 21  LEU B O   1 
ATOM 1130 C CB  . LEU B 1 22  ? 280.933 312.828 402.202 1.00 49.77  ? 21  LEU B CB  1 
ATOM 1131 C CG  . LEU B 1 22  ? 282.066 313.713 401.688 1.00 49.77  ? 21  LEU B CG  1 
ATOM 1132 C CD1 . LEU B 1 22  ? 283.080 312.867 400.952 1.00 49.77  ? 21  LEU B CD1 1 
ATOM 1133 C CD2 . LEU B 1 22  ? 281.534 314.803 400.784 1.00 49.77  ? 21  LEU B CD2 1 
ATOM 1134 N N   . ASN B 1 23  ? 277.730 312.511 403.183 1.00 48.46  ? 22  ASN B N   1 
ATOM 1135 C CA  . ASN B 1 23  ? 276.696 311.567 403.563 1.00 48.46  ? 22  ASN B CA  1 
ATOM 1136 C C   . ASN B 1 23  ? 276.399 310.607 402.420 1.00 48.46  ? 22  ASN B C   1 
ATOM 1137 O O   . ASN B 1 23  ? 276.376 311.019 401.257 1.00 48.46  ? 22  ASN B O   1 
ATOM 1138 C CB  . ASN B 1 23  ? 275.408 312.294 403.959 1.00 48.46  ? 22  ASN B CB  1 
ATOM 1139 C CG  . ASN B 1 23  ? 275.632 313.307 405.056 1.00 48.46  ? 22  ASN B CG  1 
ATOM 1140 O OD1 . ASN B 1 23  ? 275.415 314.502 404.865 1.00 48.46  ? 22  ASN B OD1 1 
ATOM 1141 N ND2 . ASN B 1 23  ? 276.074 312.836 406.214 1.00 48.46  ? 22  ASN B ND2 1 
ATOM 1142 N N   . PRO B 1 24  ? 276.168 309.331 402.718 1.00 47.23  ? 23  PRO B N   1 
ATOM 1143 C CA  . PRO B 1 24  ? 275.957 308.351 401.650 1.00 47.23  ? 23  PRO B CA  1 
ATOM 1144 C C   . PRO B 1 24  ? 274.684 308.629 400.871 1.00 47.23  ? 23  PRO B C   1 
ATOM 1145 O O   . PRO B 1 24  ? 273.700 309.144 401.404 1.00 47.23  ? 23  PRO B O   1 
ATOM 1146 C CB  . PRO B 1 24  ? 275.865 307.017 402.400 1.00 47.23  ? 23  PRO B CB  1 
ATOM 1147 C CG  . PRO B 1 24  ? 276.380 307.293 403.773 1.00 47.23  ? 23  PRO B CG  1 
ATOM 1148 C CD  . PRO B 1 24  ? 276.093 308.721 404.052 1.00 47.23  ? 23  PRO B CD  1 
ATOM 1149 N N   . ARG B 1 25  ? 274.713 308.275 399.586 1.00 46.32  ? 24  ARG B N   1 
ATOM 1150 C CA  . ARG B 1 25  ? 273.569 308.466 398.703 1.00 46.32  ? 24  ARG B CA  1 
ATOM 1151 C C   . ARG B 1 25  ? 273.252 307.196 397.923 1.00 46.32  ? 24  ARG B C   1 
ATOM 1152 O O   . ARG B 1 25  ? 272.716 307.260 396.816 1.00 46.32  ? 24  ARG B O   1 
ATOM 1153 C CB  . ARG B 1 25  ? 273.805 309.633 397.747 1.00 46.32  ? 24  ARG B CB  1 
ATOM 1154 C CG  . ARG B 1 25  ? 274.220 310.918 398.436 1.00 46.32  ? 24  ARG B CG  1 
ATOM 1155 C CD  . ARG B 1 25  ? 273.025 311.803 398.714 1.00 46.32  ? 24  ARG B CD  1 
ATOM 1156 N NE  . ARG B 1 25  ? 272.380 312.233 397.481 1.00 46.32  ? 24  ARG B NE  1 
ATOM 1157 C CZ  . ARG B 1 25  ? 271.141 312.696 397.407 1.00 46.32  ? 24  ARG B CZ  1 
ATOM 1158 N NH1 . ARG B 1 25  ? 270.382 312.804 398.483 1.00 46.32  ? 24  ARG B NH1 1 
ATOM 1159 N NH2 . ARG B 1 25  ? 270.653 313.057 396.224 1.00 46.32  ? 24  ARG B NH2 1 
ATOM 1160 N N   . GLY B 1 26  ? 273.583 306.037 398.483 1.00 43.82  ? 25  GLY B N   1 
ATOM 1161 C CA  . GLY B 1 26  ? 273.219 304.770 397.888 1.00 43.82  ? 25  GLY B CA  1 
ATOM 1162 C C   . GLY B 1 26  ? 274.155 304.338 396.773 1.00 43.82  ? 25  GLY B C   1 
ATOM 1163 O O   . GLY B 1 26  ? 275.040 305.066 396.329 1.00 43.82  ? 25  GLY B O   1 
ATOM 1164 N N   . VAL B 1 27  ? 273.932 303.112 396.307 1.00 40.45  ? 26  VAL B N   1 
ATOM 1165 C CA  . VAL B 1 27  ? 274.724 302.496 395.249 1.00 40.45  ? 26  VAL B CA  1 
ATOM 1166 C C   . VAL B 1 27  ? 273.813 302.269 394.053 1.00 40.45  ? 26  VAL B C   1 
ATOM 1167 O O   . VAL B 1 27  ? 272.783 301.595 394.168 1.00 40.45  ? 26  VAL B O   1 
ATOM 1168 C CB  . VAL B 1 27  ? 275.353 301.175 395.715 1.00 40.45  ? 26  VAL B CB  1 
ATOM 1169 C CG1 . VAL B 1 27  ? 276.179 300.563 394.604 1.00 40.45  ? 26  VAL B CG1 1 
ATOM 1170 C CG2 . VAL B 1 27  ? 276.191 301.399 396.957 1.00 40.45  ? 26  VAL B CG2 1 
ATOM 1171 N N   . ASN B 1 28  ? 274.189 302.822 392.909 1.00 42.83  ? 27  ASN B N   1 
ATOM 1172 C CA  . ASN B 1 28  ? 273.383 302.687 391.702 1.00 42.83  ? 27  ASN B CA  1 
ATOM 1173 C C   . ASN B 1 28  ? 273.552 301.288 391.126 1.00 42.83  ? 27  ASN B C   1 
ATOM 1174 O O   . ASN B 1 28  ? 274.673 300.908 390.776 1.00 42.83  ? 27  ASN B O   1 
ATOM 1175 C CB  . ASN B 1 28  ? 273.801 303.733 390.679 1.00 42.83  ? 27  ASN B CB  1 
ATOM 1176 C CG  . ASN B 1 28  ? 272.941 303.712 389.435 1.00 42.83  ? 27  ASN B CG  1 
ATOM 1177 O OD1 . ASN B 1 28  ? 271.902 303.056 389.391 1.00 42.83  ? 27  ASN B OD1 1 
ATOM 1178 N ND2 . ASN B 1 28  ? 273.372 304.437 388.412 1.00 42.83  ? 27  ASN B ND2 1 
ATOM 1179 N N   . PRO B 1 29  ? 272.484 300.496 391.006 1.00 43.09  ? 28  PRO B N   1 
ATOM 1180 C CA  . PRO B 1 29  ? 272.644 299.128 390.489 1.00 43.09  ? 28  PRO B CA  1 
ATOM 1181 C C   . PRO B 1 29  ? 272.971 299.061 389.009 1.00 43.09  ? 28  PRO B C   1 
ATOM 1182 O O   . PRO B 1 29  ? 273.522 298.048 388.564 1.00 43.09  ? 28  PRO B O   1 
ATOM 1183 C CB  . PRO B 1 29  ? 271.285 298.477 390.783 1.00 43.09  ? 28  PRO B CB  1 
ATOM 1184 C CG  . PRO B 1 29  ? 270.633 299.369 391.792 1.00 43.09  ? 28  PRO B CG  1 
ATOM 1185 C CD  . PRO B 1 29  ? 271.111 300.743 391.467 1.00 43.09  ? 28  PRO B CD  1 
ATOM 1186 N N   . THR B 1 30  ? 272.651 300.097 388.232 1.00 46.76  ? 29  THR B N   1 
ATOM 1187 C CA  . THR B 1 30  ? 272.858 300.026 386.790 1.00 46.76  ? 29  THR B CA  1 
ATOM 1188 C C   . THR B 1 30  ? 274.334 300.093 386.417 1.00 46.76  ? 29  THR B C   1 
ATOM 1189 O O   . THR B 1 30  ? 274.724 299.585 385.359 1.00 46.76  ? 29  THR B O   1 
ATOM 1190 C CB  . THR B 1 30  ? 272.082 301.140 386.092 1.00 46.76  ? 29  THR B CB  1 
ATOM 1191 O OG1 . THR B 1 30  ? 272.443 302.406 386.659 1.00 46.76  ? 29  THR B OG1 1 
ATOM 1192 C CG2 . THR B 1 30  ? 270.589 300.927 386.256 1.00 46.76  ? 29  THR B CG2 1 
ATOM 1193 N N   . ASN B 1 31  ? 275.167 300.714 387.253 1.00 45.80  ? 30  ASN B N   1 
ATOM 1194 C CA  . ASN B 1 31  ? 276.596 300.780 386.987 1.00 45.80  ? 30  ASN B CA  1 
ATOM 1195 C C   . ASN B 1 31  ? 277.461 300.538 388.216 1.00 45.80  ? 30  ASN B C   1 
ATOM 1196 O O   . ASN B 1 31  ? 278.689 300.562 388.098 1.00 45.80  ? 30  ASN B O   1 
ATOM 1197 C CB  . ASN B 1 31  ? 276.965 302.135 386.366 1.00 45.80  ? 30  ASN B CB  1 
ATOM 1198 C CG  . ASN B 1 31  ? 276.282 303.292 387.053 1.00 45.80  ? 30  ASN B CG  1 
ATOM 1199 O OD1 . ASN B 1 31  ? 275.723 303.142 388.135 1.00 45.80  ? 30  ASN B OD1 1 
ATOM 1200 N ND2 . ASN B 1 31  ? 276.324 304.461 386.425 1.00 45.80  ? 30  ASN B ND2 1 
ATOM 1201 N N   . GLY B 1 32  ? 276.866 300.304 389.382 1.00 42.29  ? 31  GLY B N   1 
ATOM 1202 C CA  . GLY B 1 32  ? 277.640 299.975 390.563 1.00 42.29  ? 31  GLY B CA  1 
ATOM 1203 C C   . GLY B 1 32  ? 278.502 301.096 391.093 1.00 42.29  ? 31  GLY B C   1 
ATOM 1204 O O   . GLY B 1 32  ? 279.582 300.835 391.627 1.00 42.29  ? 31  GLY B O   1 
ATOM 1205 N N   . VAL B 1 33  ? 278.048 302.337 390.973 1.00 38.54  ? 32  VAL B N   1 
ATOM 1206 C CA  . VAL B 1 33  ? 278.813 303.504 391.392 1.00 38.54  ? 32  VAL B CA  1 
ATOM 1207 C C   . VAL B 1 33  ? 278.237 304.000 392.711 1.00 38.54  ? 32  VAL B C   1 
ATOM 1208 O O   . VAL B 1 33  ? 277.134 304.554 392.749 1.00 38.54  ? 32  VAL B O   1 
ATOM 1209 C CB  . VAL B 1 33  ? 278.783 304.604 390.323 1.00 38.54  ? 32  VAL B CB  1 
ATOM 1210 C CG1 . VAL B 1 33  ? 279.362 305.883 390.868 1.00 38.54  ? 32  VAL B CG1 1 
ATOM 1211 C CG2 . VAL B 1 33  ? 279.540 304.161 389.089 1.00 38.54  ? 32  VAL B CG2 1 
ATOM 1212 N N   . ALA B 1 34  ? 278.979 303.806 393.797 1.00 36.63  ? 33  ALA B N   1 
ATOM 1213 C CA  . ALA B 1 34  ? 278.594 304.382 395.075 1.00 36.63  ? 33  ALA B CA  1 
ATOM 1214 C C   . ALA B 1 34  ? 278.813 305.888 395.056 1.00 36.63  ? 33  ALA B C   1 
ATOM 1215 O O   . ALA B 1 34  ? 279.734 306.392 394.413 1.00 36.63  ? 33  ALA B O   1 
ATOM 1216 C CB  . ALA B 1 34  ? 279.391 303.751 396.211 1.00 36.63  ? 33  ALA B CB  1 
ATOM 1217 N N   . SER B 1 35  ? 277.953 306.613 395.765 1.00 41.13  ? 34  SER B N   1 
ATOM 1218 C CA  . SER B 1 35  ? 277.988 308.068 395.757 1.00 41.13  ? 34  SER B CA  1 
ATOM 1219 C C   . SER B 1 35  ? 277.982 308.612 397.175 1.00 41.13  ? 34  SER B C   1 
ATOM 1220 O O   . SER B 1 35  ? 277.260 308.113 398.040 1.00 41.13  ? 34  SER B O   1 
ATOM 1221 C CB  . SER B 1 35  ? 276.803 308.648 394.982 1.00 41.13  ? 34  SER B CB  1 
ATOM 1222 O OG  . SER B 1 35  ? 276.958 308.446 393.591 1.00 41.13  ? 34  SER B OG  1 
ATOM 1223 N N   . LEU B 1 36  ? 278.795 309.638 397.401 1.00 42.71  ? 35  LEU B N   1 
ATOM 1224 C CA  . LEU B 1 36  ? 278.813 310.387 398.648 1.00 42.71  ? 35  LEU B CA  1 
ATOM 1225 C C   . LEU B 1 36  ? 278.655 311.859 398.313 1.00 42.71  ? 35  LEU B C   1 
ATOM 1226 O O   . LEU B 1 36  ? 279.361 312.375 397.443 1.00 42.71  ? 35  LEU B O   1 
ATOM 1227 C CB  . LEU B 1 36  ? 280.115 310.157 399.415 1.00 42.71  ? 35  LEU B CB  1 
ATOM 1228 C CG  . LEU B 1 36  ? 280.409 308.738 399.883 1.00 42.71  ? 35  LEU B CG  1 
ATOM 1229 C CD1 . LEU B 1 36  ? 281.894 308.576 400.093 1.00 42.71  ? 35  LEU B CD1 1 
ATOM 1230 C CD2 . LEU B 1 36  ? 279.670 308.459 401.167 1.00 42.71  ? 35  LEU B CD2 1 
ATOM 1231 N N   . SER B 1 37  ? 277.737 312.533 398.993 1.00 49.19  ? 36  SER B N   1 
ATOM 1232 C CA  . SER B 1 37  ? 277.454 313.931 398.716 1.00 49.19  ? 36  SER B CA  1 
ATOM 1233 C C   . SER B 1 37  ? 277.454 314.724 400.011 1.00 49.19  ? 36  SER B C   1 
ATOM 1234 O O   . SER B 1 37  ? 277.450 314.167 401.111 1.00 49.19  ? 36  SER B O   1 
ATOM 1235 C CB  . SER B 1 37  ? 276.115 314.103 397.996 1.00 49.19  ? 36  SER B CB  1 
ATOM 1236 O OG  . SER B 1 37  ? 275.673 315.445 398.081 1.00 49.19  ? 36  SER B OG  1 
ATOM 1237 N N   . GLN B 1 38  ? 277.471 316.042 399.867 1.00 54.00  ? 37  GLN B N   1 
ATOM 1238 C CA  . GLN B 1 38  ? 277.404 316.949 401.000 1.00 54.00  ? 37  GLN B CA  1 
ATOM 1239 C C   . GLN B 1 38  ? 275.950 317.301 401.302 1.00 54.00  ? 37  GLN B C   1 
ATOM 1240 O O   . GLN B 1 38  ? 275.039 317.029 400.518 1.00 54.00  ? 37  GLN B O   1 
ATOM 1241 C CB  . GLN B 1 38  ? 278.218 318.209 400.719 1.00 54.00  ? 37  GLN B CB  1 
ATOM 1242 C CG  . GLN B 1 38  ? 278.792 318.873 401.951 1.00 54.00  ? 37  GLN B CG  1 
ATOM 1243 C CD  . GLN B 1 38  ? 279.249 320.288 401.679 1.00 54.00  ? 37  GLN B CD  1 
ATOM 1244 O OE1 . GLN B 1 38  ? 278.766 320.940 400.755 1.00 54.00  ? 37  GLN B OE1 1 
ATOM 1245 N NE2 . GLN B 1 38  ? 280.174 320.777 402.493 1.00 54.00  ? 37  GLN B NE2 1 
ATOM 1246 N N   . ALA B 1 39  ? 275.737 317.917 402.461 1.00 59.71  ? 38  ALA B N   1 
ATOM 1247 C CA  . ALA B 1 39  ? 274.400 318.277 402.912 1.00 59.71  ? 38  ALA B CA  1 
ATOM 1248 C C   . ALA B 1 39  ? 273.963 319.564 402.224 1.00 59.71  ? 38  ALA B C   1 
ATOM 1249 O O   . ALA B 1 39  ? 274.670 320.576 402.281 1.00 59.71  ? 38  ALA B O   1 
ATOM 1250 C CB  . ALA B 1 39  ? 274.368 318.439 404.430 1.00 59.71  ? 38  ALA B CB  1 
ATOM 1251 N N   . GLY B 1 40  ? 272.800 319.524 401.578 1.00 59.83  ? 39  GLY B N   1 
ATOM 1252 C CA  . GLY B 1 40  ? 272.272 320.684 400.889 1.00 59.83  ? 39  GLY B CA  1 
ATOM 1253 C C   . GLY B 1 40  ? 270.940 320.414 400.222 1.00 59.83  ? 39  GLY B C   1 
ATOM 1254 O O   . GLY B 1 40  ? 270.690 319.300 399.753 1.00 59.83  ? 39  GLY B O   1 
ATOM 1255 N N   . ALA B 1 41  ? 270.072 321.426 400.173 1.00 57.68  ? 40  ALA B N   1 
ATOM 1256 C CA  . ALA B 1 41  ? 268.757 321.240 399.568 1.00 57.68  ? 40  ALA B CA  1 
ATOM 1257 C C   . ALA B 1 41  ? 268.842 321.182 398.048 1.00 57.68  ? 40  ALA B C   1 
ATOM 1258 O O   . ALA B 1 41  ? 268.192 320.341 397.418 1.00 57.68  ? 40  ALA B O   1 
ATOM 1259 C CB  . ALA B 1 41  ? 267.814 322.358 400.008 1.00 57.68  ? 40  ALA B CB  1 
ATOM 1260 N N   . VAL B 1 42  ? 269.635 322.062 397.444 1.00 50.44  ? 41  VAL B N   1 
ATOM 1261 C CA  . VAL B 1 42  ? 269.705 322.173 395.989 1.00 50.44  ? 41  VAL B CA  1 
ATOM 1262 C C   . VAL B 1 42  ? 270.616 321.087 395.428 1.00 50.44  ? 41  VAL B C   1 
ATOM 1263 O O   . VAL B 1 42  ? 271.781 320.984 395.835 1.00 50.44  ? 41  VAL B O   1 
ATOM 1264 C CB  . VAL B 1 42  ? 270.182 323.568 395.564 1.00 50.44  ? 41  VAL B CB  1 
ATOM 1265 C CG1 . VAL B 1 42  ? 270.179 323.683 394.057 1.00 50.44  ? 41  VAL B CG1 1 
ATOM 1266 C CG2 . VAL B 1 42  ? 269.294 324.629 396.178 1.00 50.44  ? 41  VAL B CG2 1 
ATOM 1267 N N   . PRO B 1 43  ? 270.127 320.255 394.508 1.00 48.38  ? 42  PRO B N   1 
ATOM 1268 C CA  . PRO B 1 43  ? 270.976 319.188 393.954 1.00 48.38  ? 42  PRO B CA  1 
ATOM 1269 C C   . PRO B 1 43  ? 272.183 319.689 393.181 1.00 48.38  ? 42  PRO B C   1 
ATOM 1270 O O   . PRO B 1 43  ? 273.175 318.960 393.074 1.00 48.38  ? 42  PRO B O   1 
ATOM 1271 C CB  . PRO B 1 43  ? 270.014 318.416 393.043 1.00 48.38  ? 42  PRO B CB  1 
ATOM 1272 C CG  . PRO B 1 43  ? 268.656 318.744 393.546 1.00 48.38  ? 42  PRO B CG  1 
ATOM 1273 C CD  . PRO B 1 43  ? 268.732 320.144 394.057 1.00 48.38  ? 42  PRO B CD  1 
ATOM 1274 N N   . ALA B 1 44  ? 272.134 320.900 392.629 1.00 47.02  ? 43  ALA B N   1 
ATOM 1275 C CA  . ALA B 1 44  ? 273.192 321.359 391.737 1.00 47.02  ? 43  ALA B CA  1 
ATOM 1276 C C   . ALA B 1 44  ? 274.354 322.029 392.457 1.00 47.02  ? 43  ALA B C   1 
ATOM 1277 O O   . ALA B 1 44  ? 275.359 322.334 391.810 1.00 47.02  ? 43  ALA B O   1 
ATOM 1278 C CB  . ALA B 1 44  ? 272.620 322.323 390.698 1.00 47.02  ? 43  ALA B CB  1 
ATOM 1279 N N   . LEU B 1 45  ? 274.252 322.266 393.762 1.00 50.21  ? 44  LEU B N   1 
ATOM 1280 C CA  . LEU B 1 45  ? 275.308 322.928 394.516 1.00 50.21  ? 44  LEU B CA  1 
ATOM 1281 C C   . LEU B 1 45  ? 276.024 321.990 395.478 1.00 50.21  ? 44  LEU B C   1 
ATOM 1282 O O   . LEU B 1 45  ? 276.705 322.461 396.393 1.00 50.21  ? 44  LEU B O   1 
ATOM 1283 C CB  . LEU B 1 45  ? 274.739 324.124 395.280 1.00 50.21  ? 44  LEU B CB  1 
ATOM 1284 C CG  . LEU B 1 45  ? 273.934 325.127 394.456 1.00 50.21  ? 44  LEU B CG  1 
ATOM 1285 C CD1 . LEU B 1 45  ? 273.374 326.220 395.344 1.00 50.21  ? 44  LEU B CD1 1 
ATOM 1286 C CD2 . LEU B 1 45  ? 274.789 325.719 393.357 1.00 50.21  ? 44  LEU B CD2 1 
ATOM 1287 N N   . GLU B 1 46  ? 275.891 320.683 395.294 1.00 49.93  ? 45  GLU B N   1 
ATOM 1288 C CA  . GLU B 1 46  ? 276.487 319.706 396.189 1.00 49.93  ? 45  GLU B CA  1 
ATOM 1289 C C   . GLU B 1 46  ? 277.895 319.336 395.736 1.00 49.93  ? 45  GLU B C   1 
ATOM 1290 O O   . GLU B 1 46  ? 278.244 319.440 394.559 1.00 49.93  ? 45  GLU B O   1 
ATOM 1291 C CB  . GLU B 1 46  ? 275.624 318.448 396.257 1.00 49.93  ? 45  GLU B CB  1 
ATOM 1292 C CG  . GLU B 1 46  ? 274.405 318.570 397.145 1.00 49.93  ? 45  GLU B CG  1 
ATOM 1293 C CD  . GLU B 1 46  ? 273.411 317.450 396.912 1.00 49.93  ? 45  GLU B CD  1 
ATOM 1294 O OE1 . GLU B 1 46  ? 273.470 316.821 395.835 1.00 49.93  ? 45  GLU B OE1 1 
ATOM 1295 O OE2 . GLU B 1 46  ? 272.571 317.201 397.802 1.00 49.93  ? 45  GLU B OE2 1 
ATOM 1296 N N   . LYS B 1 47  ? 278.703 318.891 396.695 1.00 45.63  ? 46  LYS B N   1 
ATOM 1297 C CA  . LYS B 1 47  ? 280.018 318.323 396.425 1.00 45.63  ? 46  LYS B CA  1 
ATOM 1298 C C   . LYS B 1 47  ? 279.889 316.807 396.443 1.00 45.63  ? 46  LYS B C   1 
ATOM 1299 O O   . LYS B 1 47  ? 279.494 316.230 397.460 1.00 45.63  ? 46  LYS B O   1 
ATOM 1300 C CB  . LYS B 1 47  ? 281.037 318.784 397.463 1.00 45.63  ? 46  LYS B CB  1 
ATOM 1301 C CG  . LYS B 1 47  ? 281.515 320.209 397.289 1.00 45.63  ? 46  LYS B CG  1 
ATOM 1302 C CD  . LYS B 1 47  ? 282.452 320.601 398.417 1.00 45.63  ? 46  LYS B CD  1 
ATOM 1303 C CE  . LYS B 1 47  ? 282.868 322.055 398.312 1.00 45.63  ? 46  LYS B CE  1 
ATOM 1304 N NZ  . LYS B 1 47  ? 282.916 322.712 399.645 1.00 45.63  ? 46  LYS B NZ  1 
ATOM 1305 N N   . ARG B 1 48  ? 280.223 316.164 395.329 1.00 43.20  ? 47  ARG B N   1 
ATOM 1306 C CA  . ARG B 1 48  ? 279.980 314.740 395.150 1.00 43.20  ? 47  ARG B CA  1 
ATOM 1307 C C   . ARG B 1 48  ? 281.288 313.972 395.038 1.00 43.20  ? 47  ARG B C   1 
ATOM 1308 O O   . ARG B 1 48  ? 282.253 314.451 394.439 1.00 43.20  ? 47  ARG B O   1 
ATOM 1309 C CB  . ARG B 1 48  ? 279.136 314.479 393.904 1.00 43.20  ? 47  ARG B CB  1 
ATOM 1310 C CG  . ARG B 1 48  ? 278.076 315.523 393.646 1.00 43.20  ? 47  ARG B CG  1 
ATOM 1311 C CD  . ARG B 1 48  ? 277.489 315.367 392.255 1.00 43.20  ? 47  ARG B CD  1 
ATOM 1312 N NE  . ARG B 1 48  ? 276.347 316.248 392.040 1.00 43.20  ? 47  ARG B NE  1 
ATOM 1313 C CZ  . ARG B 1 48  ? 276.439 317.546 391.783 1.00 43.20  ? 47  ARG B CZ  1 
ATOM 1314 N NH1 . ARG B 1 48  ? 277.610 318.154 391.694 1.00 43.20  ? 47  ARG B NH1 1 
ATOM 1315 N NH2 . ARG B 1 48  ? 275.326 318.251 391.612 1.00 43.20  ? 47  ARG B NH2 1 
ATOM 1316 N N   . VAL B 1 49  ? 281.307 312.776 395.620 1.00 37.16  ? 48  VAL B N   1 
ATOM 1317 C CA  . VAL B 1 49  ? 282.396 311.821 395.467 1.00 37.16  ? 48  VAL B CA  1 
ATOM 1318 C C   . VAL B 1 49  ? 281.792 310.485 395.065 1.00 37.16  ? 48  VAL B C   1 
ATOM 1319 O O   . VAL B 1 49  ? 280.916 309.965 395.763 1.00 37.16  ? 48  VAL B O   1 
ATOM 1320 C CB  . VAL B 1 49  ? 283.216 311.671 396.759 1.00 37.16  ? 48  VAL B CB  1 
ATOM 1321 C CG1 . VAL B 1 49  ? 284.277 310.611 396.587 1.00 37.16  ? 48  VAL B CG1 1 
ATOM 1322 C CG2 . VAL B 1 49  ? 283.845 312.992 397.140 1.00 37.16  ? 48  VAL B CG2 1 
ATOM 1323 N N   . THR B 1 50  ? 282.249 309.932 393.945 1.00 34.28  ? 49  THR B N   1 
ATOM 1324 C CA  . THR B 1 50  ? 281.750 308.657 393.447 1.00 34.28  ? 49  THR B CA  1 
ATOM 1325 C C   . THR B 1 50  ? 282.911 307.688 393.299 1.00 34.28  ? 49  THR B C   1 
ATOM 1326 O O   . THR B 1 50  ? 283.966 308.058 392.781 1.00 34.28  ? 49  THR B O   1 
ATOM 1327 C CB  . THR B 1 50  ? 281.039 308.810 392.102 1.00 34.28  ? 49  THR B CB  1 
ATOM 1328 O OG1 . THR B 1 50  ? 282.011 308.921 391.059 1.00 34.28  ? 49  THR B OG1 1 
ATOM 1329 C CG2 . THR B 1 50  ? 280.159 310.047 392.096 1.00 34.28  ? 49  THR B CG2 1 
ATOM 1330 N N   . VAL B 1 51  ? 282.714 306.451 393.745 1.00 31.43  ? 50  VAL B N   1 
ATOM 1331 C CA  . VAL B 1 51  ? 283.738 305.416 393.697 1.00 31.43  ? 50  VAL B CA  1 
ATOM 1332 C C   . VAL B 1 51  ? 283.120 304.138 393.143 1.00 31.43  ? 50  VAL B C   1 
ATOM 1333 O O   . VAL B 1 51  ? 281.945 303.850 393.393 1.00 31.43  ? 50  VAL B O   1 
ATOM 1334 C CB  . VAL B 1 51  ? 284.362 305.180 395.089 1.00 31.43  ? 50  VAL B CB  1 
ATOM 1335 C CG1 . VAL B 1 51  ? 283.333 304.647 396.054 1.00 31.43  ? 50  VAL B CG1 1 
ATOM 1336 C CG2 . VAL B 1 51  ? 285.537 304.230 394.996 1.00 31.43  ? 50  VAL B CG2 1 
ATOM 1337 N N   . SER B 1 52  ? 283.899 303.388 392.367 1.00 34.47  ? 51  SER B N   1 
ATOM 1338 C CA  . SER B 1 52  ? 283.417 302.140 391.794 1.00 34.47  ? 51  SER B CA  1 
ATOM 1339 C C   . SER B 1 52  ? 284.572 301.162 391.664 1.00 34.47  ? 51  SER B C   1 
ATOM 1340 O O   . SER B 1 52  ? 285.741 301.549 391.654 1.00 34.47  ? 51  SER B O   1 
ATOM 1341 C CB  . SER B 1 52  ? 282.769 302.356 390.426 1.00 34.47  ? 51  SER B CB  1 
ATOM 1342 O OG  . SER B 1 52  ? 283.753 302.456 389.415 1.00 34.47  ? 51  SER B OG  1 
ATOM 1343 N N   . VAL B 1 53  ? 284.228 299.879 391.571 1.00 39.13  ? 52  VAL B N   1 
ATOM 1344 C CA  . VAL B 1 53  ? 285.177 298.814 391.267 1.00 39.13  ? 52  VAL B CA  1 
ATOM 1345 C C   . VAL B 1 53  ? 284.582 297.975 390.148 1.00 39.13  ? 52  VAL B C   1 
ATOM 1346 O O   . VAL B 1 53  ? 283.404 297.608 390.205 1.00 39.13  ? 52  VAL B O   1 
ATOM 1347 C CB  . VAL B 1 53  ? 285.483 297.939 392.496 1.00 39.13  ? 52  VAL B CB  1 
ATOM 1348 C CG1 . VAL B 1 53  ? 286.492 296.869 392.138 1.00 39.13  ? 52  VAL B CG1 1 
ATOM 1349 C CG2 . VAL B 1 53  ? 285.988 298.790 393.641 1.00 39.13  ? 52  VAL B CG2 1 
ATOM 1350 N N   . SER B 1 54  ? 285.385 297.681 389.131 1.00 47.28  ? 53  SER B N   1 
ATOM 1351 C CA  . SER B 1 54  ? 284.915 296.999 387.929 1.00 47.28  ? 53  SER B CA  1 
ATOM 1352 C C   . SER B 1 54  ? 285.574 295.631 387.836 1.00 47.28  ? 53  SER B C   1 
ATOM 1353 O O   . SER B 1 54  ? 286.782 295.534 387.604 1.00 47.28  ? 53  SER B O   1 
ATOM 1354 C CB  . SER B 1 54  ? 285.213 297.831 386.685 1.00 47.28  ? 53  SER B CB  1 
ATOM 1355 O OG  . SER B 1 54  ? 284.788 297.161 385.514 1.00 47.28  ? 53  SER B OG  1 
ATOM 1356 N N   . GLN B 1 55  ? 284.779 294.578 388.007 1.00 53.78  ? 54  GLN B N   1 
ATOM 1357 C CA  . GLN B 1 55  ? 285.290 293.225 387.889 1.00 53.78  ? 54  GLN B CA  1 
ATOM 1358 C C   . GLN B 1 55  ? 285.666 292.929 386.438 1.00 53.78  ? 54  GLN B C   1 
ATOM 1359 O O   . GLN B 1 55  ? 285.032 293.435 385.510 1.00 53.78  ? 54  GLN B O   1 
ATOM 1360 C CB  . GLN B 1 55  ? 284.252 292.216 388.371 1.00 53.78  ? 54  GLN B CB  1 
ATOM 1361 C CG  . GLN B 1 55  ? 284.252 291.975 389.873 1.00 53.78  ? 54  GLN B CG  1 
ATOM 1362 C CD  . GLN B 1 55  ? 283.789 293.184 390.665 1.00 53.78  ? 54  GLN B CD  1 
ATOM 1363 O OE1 . GLN B 1 55  ? 284.432 293.591 391.632 1.00 53.78  ? 54  GLN B OE1 1 
ATOM 1364 N NE2 . GLN B 1 55  ? 282.665 293.762 390.259 1.00 53.78  ? 54  GLN B NE2 1 
ATOM 1365 N N   . PRO B 1 56  ? 286.696 292.118 386.217 1.00 55.21  ? 55  PRO B N   1 
ATOM 1366 C CA  . PRO B 1 56  ? 287.132 291.848 384.845 1.00 55.21  ? 55  PRO B CA  1 
ATOM 1367 C C   . PRO B 1 56  ? 286.097 291.062 384.060 1.00 55.21  ? 55  PRO B C   1 
ATOM 1368 O O   . PRO B 1 56  ? 285.342 290.256 384.607 1.00 55.21  ? 55  PRO B O   1 
ATOM 1369 C CB  . PRO B 1 56  ? 288.417 291.035 385.033 1.00 55.21  ? 55  PRO B CB  1 
ATOM 1370 C CG  . PRO B 1 56  ? 288.296 290.436 386.372 1.00 55.21  ? 55  PRO B CG  1 
ATOM 1371 C CD  . PRO B 1 56  ? 287.505 291.392 387.208 1.00 55.21  ? 55  PRO B CD  1 
ATOM 1372 N N   . SER B 1 57  ? 286.072 291.312 382.756 1.00 67.40  ? 56  SER B N   1 
ATOM 1373 C CA  . SER B 1 57  ? 285.220 290.600 381.817 1.00 67.40  ? 56  SER B CA  1 
ATOM 1374 C C   . SER B 1 57  ? 286.085 290.081 380.676 1.00 67.40  ? 56  SER B C   1 
ATOM 1375 O O   . SER B 1 57  ? 287.311 290.224 380.684 1.00 67.40  ? 56  SER B O   1 
ATOM 1376 C CB  . SER B 1 57  ? 284.094 291.499 381.291 1.00 67.40  ? 56  SER B CB  1 
ATOM 1377 O OG  . SER B 1 57  ? 284.612 292.716 380.783 1.00 67.40  ? 56  SER B OG  1 
ATOM 1378 N N   . ARG B 1 58  ? 285.439 289.470 379.681 1.00 73.14  ? 57  ARG B N   1 
ATOM 1379 C CA  . ARG B 1 58  ? 286.189 288.936 378.549 1.00 73.14  ? 57  ARG B CA  1 
ATOM 1380 C C   . ARG B 1 58  ? 286.794 290.044 377.698 1.00 73.14  ? 57  ARG B C   1 
ATOM 1381 O O   . ARG B 1 58  ? 287.807 289.823 377.025 1.00 73.14  ? 57  ARG B O   1 
ATOM 1382 C CB  . ARG B 1 58  ? 285.293 288.037 377.697 1.00 73.14  ? 57  ARG B CB  1 
ATOM 1383 C CG  . ARG B 1 58  ? 284.066 288.727 377.129 1.00 73.14  ? 57  ARG B CG  1 
ATOM 1384 C CD  . ARG B 1 58  ? 283.217 287.746 376.338 1.00 73.14  ? 57  ARG B CD  1 
ATOM 1385 N NE  . ARG B 1 58  ? 282.039 288.374 375.754 1.00 73.14  ? 57  ARG B NE  1 
ATOM 1386 C CZ  . ARG B 1 58  ? 280.863 288.465 376.361 1.00 73.14  ? 57  ARG B CZ  1 
ATOM 1387 N NH1 . ARG B 1 58  ? 280.676 287.990 377.581 1.00 73.14  ? 57  ARG B NH1 1 
ATOM 1388 N NH2 . ARG B 1 58  ? 279.849 289.045 375.726 1.00 73.14  ? 57  ARG B NH2 1 
ATOM 1389 N N   . ASN B 1 59  ? 286.193 291.234 377.707 1.00 70.36  ? 58  ASN B N   1 
ATOM 1390 C CA  . ASN B 1 59  ? 286.720 292.333 376.907 1.00 70.36  ? 58  ASN B CA  1 
ATOM 1391 C C   . ASN B 1 59  ? 287.948 292.982 377.542 1.00 70.36  ? 58  ASN B C   1 
ATOM 1392 O O   . ASN B 1 59  ? 288.882 293.366 376.830 1.00 70.36  ? 58  ASN B O   1 
ATOM 1393 C CB  . ASN B 1 59  ? 285.618 293.367 376.654 1.00 70.36  ? 58  ASN B CB  1 
ATOM 1394 C CG  . ASN B 1 59  ? 285.114 294.027 377.931 1.00 70.36  ? 58  ASN B CG  1 
ATOM 1395 O OD1 . ASN B 1 59  ? 285.653 293.818 379.018 1.00 70.36  ? 58  ASN B OD1 1 
ATOM 1396 N ND2 . ASN B 1 59  ? 284.067 294.832 377.798 1.00 70.36  ? 58  ASN B ND2 1 
ATOM 1397 N N   . ARG B 1 60  ? 287.974 293.111 378.869 1.00 61.44  ? 59  ARG B N   1 
ATOM 1398 C CA  . ARG B 1 60  ? 289.010 293.880 379.554 1.00 61.44  ? 59  ARG B CA  1 
ATOM 1399 C C   . ARG B 1 60  ? 289.953 293.038 380.399 1.00 61.44  ? 59  ARG B C   1 
ATOM 1400 O O   . ARG B 1 60  ? 291.142 293.356 380.478 1.00 61.44  ? 59  ARG B O   1 
ATOM 1401 C CB  . ARG B 1 60  ? 288.370 294.951 380.444 1.00 61.44  ? 59  ARG B CB  1 
ATOM 1402 C CG  . ARG B 1 60  ? 289.354 296.007 380.923 1.00 61.44  ? 59  ARG B CG  1 
ATOM 1403 C CD  . ARG B 1 60  ? 288.982 296.547 382.290 1.00 61.44  ? 59  ARG B CD  1 
ATOM 1404 N NE  . ARG B 1 60  ? 287.583 296.948 382.364 1.00 61.44  ? 59  ARG B NE  1 
ATOM 1405 C CZ  . ARG B 1 60  ? 286.703 296.437 383.212 1.00 61.44  ? 59  ARG B CZ  1 
ATOM 1406 N NH1 . ARG B 1 60  ? 287.038 295.482 384.063 1.00 61.44  ? 59  ARG B NH1 1 
ATOM 1407 N NH2 . ARG B 1 60  ? 285.454 296.895 383.205 1.00 61.44  ? 59  ARG B NH2 1 
ATOM 1408 N N   . LYS B 1 61  ? 289.445 291.984 381.036 1.00 60.70  ? 60  LYS B N   1 
ATOM 1409 C CA  . LYS B 1 61  ? 290.214 291.068 381.893 1.00 60.70  ? 60  LYS B CA  1 
ATOM 1410 C C   . LYS B 1 61  ? 291.190 291.797 382.821 1.00 60.70  ? 60  LYS B C   1 
ATOM 1411 O O   . LYS B 1 61  ? 292.289 291.324 383.108 1.00 60.70  ? 60  LYS B O   1 
ATOM 1412 C CB  . LYS B 1 61  ? 290.927 289.990 381.060 1.00 60.70  ? 60  LYS B CB  1 
ATOM 1413 C CG  . LYS B 1 61  ? 291.833 290.461 379.919 1.00 60.70  ? 60  LYS B CG  1 
ATOM 1414 C CD  . LYS B 1 61  ? 293.280 290.625 380.341 1.00 60.70  ? 60  LYS B CD  1 
ATOM 1415 C CE  . LYS B 1 61  ? 294.175 290.880 379.145 1.00 60.70  ? 60  LYS B CE  1 
ATOM 1416 N NZ  . LYS B 1 61  ? 295.606 290.973 379.540 1.00 60.70  ? 60  LYS B NZ  1 
ATOM 1417 N N   . ASN B 1 62  ? 290.744 292.935 383.352 1.00 52.56  ? 61  ASN B N   1 
ATOM 1418 C CA  . ASN B 1 62  ? 291.500 293.678 384.353 1.00 52.56  ? 61  ASN B CA  1 
ATOM 1419 C C   . ASN B 1 62  ? 290.542 294.264 385.377 1.00 52.56  ? 61  ASN B C   1 
ATOM 1420 O O   . ASN B 1 62  ? 289.362 294.488 385.098 1.00 52.56  ? 61  ASN B O   1 
ATOM 1421 C CB  . ASN B 1 62  ? 292.334 294.807 383.735 1.00 52.56  ? 61  ASN B CB  1 
ATOM 1422 C CG  . ASN B 1 62  ? 293.761 294.397 383.444 1.00 52.56  ? 61  ASN B CG  1 
ATOM 1423 O OD1 . ASN B 1 62  ? 294.669 295.221 383.419 1.00 52.56  ? 61  ASN B OD1 1 
ATOM 1424 N ND2 . ASN B 1 62  ? 293.961 293.108 383.210 1.00 52.56  ? 61  ASN B ND2 1 
ATOM 1425 N N   . TYR B 1 63  ? 291.069 294.516 386.569 1.00 44.52  ? 62  TYR B N   1 
ATOM 1426 C CA  . TYR B 1 63  ? 290.339 295.226 387.608 1.00 44.52  ? 62  TYR B CA  1 
ATOM 1427 C C   . TYR B 1 63  ? 290.560 296.721 387.450 1.00 44.52  ? 62  TYR B C   1 
ATOM 1428 O O   . TYR B 1 63  ? 291.679 297.168 387.194 1.00 44.52  ? 62  TYR B O   1 
ATOM 1429 C CB  . TYR B 1 63  ? 290.792 294.777 388.995 1.00 44.52  ? 62  TYR B CB  1 
ATOM 1430 C CG  . TYR B 1 63  ? 290.340 293.391 389.370 1.00 44.52  ? 62  TYR B CG  1 
ATOM 1431 C CD1 . TYR B 1 63  ? 291.052 292.276 388.964 1.00 44.52  ? 62  TYR B CD1 1 
ATOM 1432 C CD2 . TYR B 1 63  ? 289.205 293.198 390.141 1.00 44.52  ? 62  TYR B CD2 1 
ATOM 1433 C CE1 . TYR B 1 63  ? 290.643 291.009 389.307 1.00 44.52  ? 62  TYR B CE1 1 
ATOM 1434 C CE2 . TYR B 1 63  ? 288.790 291.934 390.491 1.00 44.52  ? 62  TYR B CE2 1 
ATOM 1435 C CZ  . TYR B 1 63  ? 289.513 290.843 390.072 1.00 44.52  ? 62  TYR B CZ  1 
ATOM 1436 O OH  . TYR B 1 63  ? 289.102 289.579 390.417 1.00 44.52  ? 62  TYR B OH  1 
ATOM 1437 N N   . LYS B 1 64  ? 289.489 297.493 387.603 1.00 40.55  ? 63  LYS B N   1 
ATOM 1438 C CA  . LYS B 1 64  ? 289.538 298.934 387.365 1.00 40.55  ? 63  LYS B CA  1 
ATOM 1439 C C   . LYS B 1 64  ? 288.793 299.643 388.490 1.00 40.55  ? 63  LYS B C   1 
ATOM 1440 O O   . LYS B 1 64  ? 287.561 299.663 388.504 1.00 40.55  ? 63  LYS B O   1 
ATOM 1441 C CB  . LYS B 1 64  ? 288.943 299.276 386.007 1.00 40.55  ? 63  LYS B CB  1 
ATOM 1442 C CG  . LYS B 1 64  ? 289.470 300.559 385.406 1.00 40.55  ? 63  LYS B CG  1 
ATOM 1443 C CD  . LYS B 1 64  ? 289.210 300.603 383.913 1.00 40.55  ? 63  LYS B CD  1 
ATOM 1444 C CE  . LYS B 1 64  ? 287.722 300.569 383.609 1.00 40.55  ? 63  LYS B CE  1 
ATOM 1445 N NZ  . LYS B 1 64  ? 287.110 301.924 383.664 1.00 40.55  ? 63  LYS B NZ  1 
ATOM 1446 N N   . VAL B 1 65  ? 289.536 300.222 389.419 1.00 31.69  ? 64  VAL B N   1 
ATOM 1447 C CA  . VAL B 1 65  ? 288.965 301.038 390.483 1.00 31.69  ? 64  VAL B CA  1 
ATOM 1448 C C   . VAL B 1 65  ? 288.993 302.493 390.048 1.00 31.69  ? 64  VAL B C   1 
ATOM 1449 O O   . VAL B 1 65  ? 290.016 302.990 389.570 1.00 31.69  ? 64  VAL B O   1 
ATOM 1450 C CB  . VAL B 1 65  ? 289.734 300.837 391.799 1.00 31.69  ? 64  VAL B CB  1 
ATOM 1451 C CG1 . VAL B 1 65  ? 289.156 301.713 392.888 1.00 31.69  ? 64  VAL B CG1 1 
ATOM 1452 C CG2 . VAL B 1 65  ? 289.699 299.385 392.206 1.00 31.69  ? 64  VAL B CG2 1 
ATOM 1453 N N   . GLN B 1 66  ? 287.869 303.183 390.207 1.00 31.48  ? 65  GLN B N   1 
ATOM 1454 C CA  . GLN B 1 66  ? 287.743 304.554 389.738 1.00 31.48  ? 65  GLN B CA  1 
ATOM 1455 C C   . GLN B 1 66  ? 287.135 305.425 390.823 1.00 31.48  ? 65  GLN B C   1 
ATOM 1456 O O   . GLN B 1 66  ? 286.232 304.995 391.543 1.00 31.48  ? 65  GLN B O   1 
ATOM 1457 C CB  . GLN B 1 66  ? 286.884 304.627 388.479 1.00 31.48  ? 65  GLN B CB  1 
ATOM 1458 C CG  . GLN B 1 66  ? 286.973 305.943 387.757 1.00 31.48  ? 65  GLN B CG  1 
ATOM 1459 C CD  . GLN B 1 66  ? 286.972 305.765 386.261 1.00 31.48  ? 65  GLN B CD  1 
ATOM 1460 O OE1 . GLN B 1 66  ? 286.965 304.642 385.761 1.00 31.48  ? 65  GLN B OE1 1 
ATOM 1461 N NE2 . GLN B 1 66  ? 286.978 306.873 385.533 1.00 31.48  ? 65  GLN B NE2 1 
ATOM 1462 N N   . VAL B 1 67  ? 287.643 306.648 390.937 1.00 29.00  ? 66  VAL B N   1 
ATOM 1463 C CA  . VAL B 1 67  ? 287.166 307.633 391.898 1.00 29.00  ? 66  VAL B CA  1 
ATOM 1464 C C   . VAL B 1 67  ? 286.992 308.954 391.166 1.00 29.00  ? 66  VAL B C   1 
ATOM 1465 O O   . VAL B 1 67  ? 287.819 309.314 390.322 1.00 29.00  ? 66  VAL B O   1 
ATOM 1466 C CB  . VAL B 1 67  ? 288.141 307.793 393.083 1.00 29.00  ? 66  VAL B CB  1 
ATOM 1467 C CG1 . VAL B 1 67  ? 287.583 308.758 394.104 1.00 29.00  ? 66  VAL B CG1 1 
ATOM 1468 C CG2 . VAL B 1 67  ? 288.422 306.455 393.725 1.00 29.00  ? 66  VAL B CG2 1 
ATOM 1469 N N   . LYS B 1 68  ? 285.917 309.671 391.474 1.00 30.84  ? 67  LYS B N   1 
ATOM 1470 C CA  . LYS B 1 68  ? 285.649 310.957 390.849 1.00 30.84  ? 67  LYS B CA  1 
ATOM 1471 C C   . LYS B 1 68  ? 285.278 311.980 391.908 1.00 30.84  ? 67  LYS B C   1 
ATOM 1472 O O   . LYS B 1 68  ? 284.707 311.645 392.947 1.00 30.84  ? 67  LYS B O   1 
ATOM 1473 C CB  . LYS B 1 68  ? 284.536 310.854 389.810 1.00 30.84  ? 67  LYS B CB  1 
ATOM 1474 C CG  . LYS B 1 68  ? 284.916 310.025 388.607 1.00 30.84  ? 67  LYS B CG  1 
ATOM 1475 C CD  . LYS B 1 68  ? 283.885 310.143 387.512 1.00 30.84  ? 67  LYS B CD  1 
ATOM 1476 C CE  . LYS B 1 68  ? 284.253 309.290 386.319 1.00 30.84  ? 67  LYS B CE  1 
ATOM 1477 N NZ  . LYS B 1 68  ? 284.245 310.082 385.062 1.00 30.84  ? 67  LYS B NZ  1 
ATOM 1478 N N   . ILE B 1 69  ? 285.618 313.235 391.633 1.00 33.68  ? 68  ILE B N   1 
ATOM 1479 C CA  . ILE B 1 69  ? 285.339 314.357 392.518 1.00 33.68  ? 68  ILE B CA  1 
ATOM 1480 C C   . ILE B 1 69  ? 284.798 315.499 391.673 1.00 33.68  ? 68  ILE B C   1 
ATOM 1481 O O   . ILE B 1 69  ? 285.299 315.758 390.574 1.00 33.68  ? 68  ILE B O   1 
ATOM 1482 C CB  . ILE B 1 69  ? 286.597 314.796 393.293 1.00 33.68  ? 68  ILE B CB  1 
ATOM 1483 C CG1 . ILE B 1 69  ? 286.973 313.747 394.336 1.00 33.68  ? 68  ILE B CG1 1 
ATOM 1484 C CG2 . ILE B 1 69  ? 286.379 316.128 393.961 1.00 33.68  ? 68  ILE B CG2 1 
ATOM 1485 C CD1 . ILE B 1 69  ? 288.201 314.101 395.126 1.00 33.68  ? 68  ILE B CD1 1 
ATOM 1486 N N   . GLN B 1 70  ? 283.764 316.169 392.174 1.00 41.39  ? 69  GLN B N   1 
ATOM 1487 C CA  . GLN B 1 70  ? 283.103 317.242 391.441 1.00 41.39  ? 69  GLN B CA  1 
ATOM 1488 C C   . GLN B 1 70  ? 282.745 318.347 392.419 1.00 41.39  ? 69  GLN B C   1 
ATOM 1489 O O   . GLN B 1 70  ? 281.939 318.133 393.326 1.00 41.39  ? 69  GLN B O   1 
ATOM 1490 C CB  . GLN B 1 70  ? 281.859 316.714 390.729 1.00 41.39  ? 69  GLN B CB  1 
ATOM 1491 C CG  . GLN B 1 70  ? 280.861 317.761 390.309 1.00 41.39  ? 69  GLN B CG  1 
ATOM 1492 C CD  . GLN B 1 70  ? 280.075 317.325 389.096 1.00 41.39  ? 69  GLN B CD  1 
ATOM 1493 O OE1 . GLN B 1 70  ? 280.138 316.166 388.691 1.00 41.39  ? 69  GLN B OE1 1 
ATOM 1494 N NE2 . GLN B 1 70  ? 279.313 318.242 388.519 1.00 41.39  ? 69  GLN B NE2 1 
ATOM 1495 N N   . ASN B 1 71  ? 283.341 319.520 392.241 1.00 41.79  ? 70  ASN B N   1 
ATOM 1496 C CA  . ASN B 1 71  ? 283.142 320.640 393.160 1.00 41.79  ? 70  ASN B CA  1 
ATOM 1497 C C   . ASN B 1 71  ? 282.613 321.857 392.419 1.00 41.79  ? 70  ASN B C   1 
ATOM 1498 O O   . ASN B 1 71  ? 283.370 322.492 391.662 1.00 41.79  ? 70  ASN B O   1 
ATOM 1499 C CB  . ASN B 1 71  ? 284.448 320.988 393.871 1.00 41.79  ? 70  ASN B CB  1 
ATOM 1500 C CG  . ASN B 1 71  ? 284.805 319.995 394.949 1.00 41.79  ? 70  ASN B CG  1 
ATOM 1501 O OD1 . ASN B 1 71  ? 284.196 318.935 395.057 1.00 41.79  ? 70  ASN B OD1 1 
ATOM 1502 N ND2 . ASN B 1 71  ? 285.794 320.335 395.762 1.00 41.79  ? 70  ASN B ND2 1 
ATOM 1503 N N   . PRO B 1 72  ? 281.347 322.222 392.588 1.00 45.52  ? 71  PRO B N   1 
ATOM 1504 C CA  . PRO B 1 72  ? 280.823 323.435 391.960 1.00 45.52  ? 71  PRO B CA  1 
ATOM 1505 C C   . PRO B 1 72  ? 280.902 324.645 392.875 1.00 45.52  ? 71  PRO B C   1 
ATOM 1506 O O   . PRO B 1 72  ? 280.866 324.542 394.102 1.00 45.52  ? 71  PRO B O   1 
ATOM 1507 C CB  . PRO B 1 72  ? 279.363 323.060 391.682 1.00 45.52  ? 71  PRO B CB  1 
ATOM 1508 C CG  . PRO B 1 72  ? 279.018 322.113 392.776 1.00 45.52  ? 71  PRO B CG  1 
ATOM 1509 C CD  . PRO B 1 72  ? 280.287 321.457 393.260 1.00 45.52  ? 71  PRO B CD  1 
ATOM 1510 N N   . THR B 1 73  ? 281.010 325.814 392.248 1.00 53.04  ? 72  THR B N   1 
ATOM 1511 C CA  . THR B 1 73  ? 280.999 327.091 392.946 1.00 53.04  ? 72  THR B CA  1 
ATOM 1512 C C   . THR B 1 73  ? 279.835 327.929 392.441 1.00 53.04  ? 72  THR B C   1 
ATOM 1513 O O   . THR B 1 73  ? 279.551 327.950 391.240 1.00 53.04  ? 72  THR B O   1 
ATOM 1514 C CB  . THR B 1 73  ? 282.307 327.856 392.746 1.00 53.04  ? 72  THR B CB  1 
ATOM 1515 O OG1 . THR B 1 73  ? 282.424 328.240 391.373 1.00 53.04  ? 72  THR B OG1 1 
ATOM 1516 C CG2 . THR B 1 73  ? 283.492 326.989 393.123 1.00 53.04  ? 72  THR B CG2 1 
ATOM 1517 N N   . ALA B 1 74  ? 279.171 328.625 393.358 1.00 62.60  ? 73  ALA B N   1 
ATOM 1518 C CA  . ALA B 1 74  ? 277.965 329.375 393.051 1.00 62.60  ? 73  ALA B CA  1 
ATOM 1519 C C   . ALA B 1 74  ? 278.116 330.831 393.467 1.00 62.60  ? 73  ALA B C   1 
ATOM 1520 O O   . ALA B 1 74  ? 278.900 331.170 394.357 1.00 62.60  ? 73  ALA B O   1 
ATOM 1521 C CB  . ALA B 1 74  ? 276.743 328.768 393.747 1.00 62.60  ? 73  ALA B CB  1 
ATOM 1522 N N   . CYS B 1 75  ? 277.343 331.691 392.809 1.00 73.51  ? 74  CYS B N   1 
ATOM 1523 C CA  . CYS B 1 75  ? 277.326 333.113 393.120 1.00 73.51  ? 74  CYS B CA  1 
ATOM 1524 C C   . CYS B 1 75  ? 276.003 333.702 392.655 1.00 73.51  ? 74  CYS B C   1 
ATOM 1525 O O   . CYS B 1 75  ? 275.412 333.234 391.679 1.00 73.51  ? 74  CYS B O   1 
ATOM 1526 C CB  . CYS B 1 75  ? 278.493 333.848 392.458 1.00 73.51  ? 74  CYS B CB  1 
ATOM 1527 S SG  . CYS B 1 75  ? 278.707 333.444 390.714 1.00 73.51  ? 74  CYS B SG  1 
ATOM 1528 N N   . THR B 1 76  ? 275.553 334.739 393.359 1.00 81.60  ? 75  THR B N   1 
ATOM 1529 C CA  . THR B 1 76  ? 274.313 335.438 393.034 1.00 81.60  ? 75  THR B CA  1 
ATOM 1530 C C   . THR B 1 76  ? 274.659 336.687 392.231 1.00 81.60  ? 75  THR B C   1 
ATOM 1531 O O   . THR B 1 76  ? 275.123 337.685 392.792 1.00 81.60  ? 75  THR B O   1 
ATOM 1532 C CB  . THR B 1 76  ? 273.543 335.808 394.300 1.00 81.60  ? 75  THR B CB  1 
ATOM 1533 O OG1 . THR B 1 76  ? 274.263 336.817 395.019 1.00 81.60  ? 75  THR B OG1 1 
ATOM 1534 C CG2 . THR B 1 76  ? 273.378 334.592 395.194 1.00 81.60  ? 75  THR B CG2 1 
ATOM 1535 N N   . ALA B 1 77  ? 274.423 336.635 390.924 1.00 86.21  ? 76  ALA B N   1 
ATOM 1536 C CA  . ALA B 1 77  ? 274.735 337.756 390.044 1.00 86.21  ? 76  ALA B CA  1 
ATOM 1537 C C   . ALA B 1 77  ? 273.754 338.905 390.242 1.00 86.21  ? 76  ALA B C   1 
ATOM 1538 O O   . ALA B 1 77  ? 272.766 338.774 390.964 1.00 86.21  ? 76  ALA B O   1 
ATOM 1539 C CB  . ALA B 1 77  ? 274.735 337.306 388.594 1.00 86.21  ? 76  ALA B CB  1 
ATOM 1540 N N   . SER B 1 80  ? 270.658 337.961 390.324 1.00 91.74  ? 79  SER B N   1 
ATOM 1541 C CA  . SER B 1 80  ? 269.397 337.230 390.323 1.00 91.74  ? 79  SER B CA  1 
ATOM 1542 C C   . SER B 1 80  ? 268.950 336.909 391.744 1.00 91.74  ? 79  SER B C   1 
ATOM 1543 O O   . SER B 1 80  ? 269.651 337.211 392.708 1.00 91.74  ? 79  SER B O   1 
ATOM 1544 C CB  . SER B 1 80  ? 269.523 335.946 389.504 1.00 91.74  ? 79  SER B CB  1 
ATOM 1545 O OG  . SER B 1 80  ? 270.000 336.223 388.200 1.00 91.74  ? 79  SER B OG  1 
ATOM 1546 N N   . CYS B 1 81  ? 267.772 336.294 391.865 1.00 90.54  ? 80  CYS B N   1 
ATOM 1547 C CA  . CYS B 1 81  ? 267.217 336.016 393.185 1.00 90.54  ? 80  CYS B CA  1 
ATOM 1548 C C   . CYS B 1 81  ? 267.991 334.913 393.898 1.00 90.54  ? 80  CYS B C   1 
ATOM 1549 O O   . CYS B 1 81  ? 268.248 335.011 395.103 1.00 90.54  ? 80  CYS B O   1 
ATOM 1550 C CB  . CYS B 1 81  ? 265.742 335.640 393.063 1.00 90.54  ? 80  CYS B CB  1 
ATOM 1551 S SG  . CYS B 1 81  ? 264.616 337.051 392.966 1.00 90.54  ? 80  CYS B SG  1 
ATOM 1552 N N   . ASP B 1 82  ? 268.373 333.862 393.176 1.00 84.26  ? 81  ASP B N   1 
ATOM 1553 C CA  . ASP B 1 82  ? 268.983 332.698 393.795 1.00 84.26  ? 81  ASP B CA  1 
ATOM 1554 C C   . ASP B 1 82  ? 270.310 332.357 393.124 1.00 84.26  ? 81  ASP B C   1 
ATOM 1555 O O   . ASP B 1 82  ? 270.489 332.609 391.929 1.00 84.26  ? 81  ASP B O   1 
ATOM 1556 C CB  . ASP B 1 82  ? 268.044 331.490 393.713 1.00 84.26  ? 81  ASP B CB  1 
ATOM 1557 C CG  . ASP B 1 82  ? 266.718 331.738 394.403 1.00 84.26  ? 81  ASP B CG  1 
ATOM 1558 O OD1 . ASP B 1 82  ? 266.705 331.844 395.646 1.00 84.26  ? 81  ASP B OD1 1 
ATOM 1559 O OD2 . ASP B 1 82  ? 265.690 331.832 393.701 1.00 84.26  ? 81  ASP B OD2 1 
ATOM 1560 N N   . PRO B 1 83  ? 271.254 331.783 393.867 1.00 75.83  ? 82  PRO B N   1 
ATOM 1561 C CA  . PRO B 1 83  ? 272.568 331.483 393.289 1.00 75.83  ? 82  PRO B CA  1 
ATOM 1562 C C   . PRO B 1 83  ? 272.490 330.431 392.197 1.00 75.83  ? 82  PRO B C   1 
ATOM 1563 O O   . PRO B 1 83  ? 271.619 329.559 392.196 1.00 75.83  ? 82  PRO B O   1 
ATOM 1564 C CB  . PRO B 1 83  ? 273.375 330.974 394.488 1.00 75.83  ? 82  PRO B CB  1 
ATOM 1565 C CG  . PRO B 1 83  ? 272.352 330.483 395.444 1.00 75.83  ? 82  PRO B CG  1 
ATOM 1566 C CD  . PRO B 1 83  ? 271.184 331.408 395.288 1.00 75.83  ? 82  PRO B CD  1 
ATOM 1567 N N   . SER B 1 84  ? 273.426 330.528 391.256 1.00 64.97  ? 83  SER B N   1 
ATOM 1568 C CA  . SER B 1 84  ? 273.559 329.584 390.161 1.00 64.97  ? 83  SER B CA  1 
ATOM 1569 C C   . SER B 1 84  ? 275.008 329.127 390.075 1.00 64.97  ? 83  SER B C   1 
ATOM 1570 O O   . SER B 1 84  ? 275.906 329.723 390.672 1.00 64.97  ? 83  SER B O   1 
ATOM 1571 C CB  . SER B 1 84  ? 273.113 330.201 388.832 1.00 64.97  ? 83  SER B CB  1 
ATOM 1572 O OG  . SER B 1 84  ? 273.411 329.338 387.750 1.00 64.97  ? 83  SER B OG  1 
ATOM 1573 N N   . VAL B 1 85  ? 275.235 328.060 389.315 1.00 57.59  ? 84  VAL B N   1 
ATOM 1574 C CA  . VAL B 1 85  ? 276.566 327.473 389.193 1.00 57.59  ? 84  VAL B CA  1 
ATOM 1575 C C   . VAL B 1 85  ? 277.377 328.277 388.186 1.00 57.59  ? 84  VAL B C   1 
ATOM 1576 O O   . VAL B 1 85  ? 276.950 328.475 387.045 1.00 57.59  ? 84  VAL B O   1 
ATOM 1577 C CB  . VAL B 1 85  ? 276.481 325.998 388.783 1.00 57.59  ? 84  VAL B CB  1 
ATOM 1578 C CG1 . VAL B 1 85  ? 277.801 325.534 388.214 1.00 57.59  ? 84  VAL B CG1 1 
ATOM 1579 C CG2 . VAL B 1 85  ? 276.094 325.145 389.972 1.00 57.59  ? 84  VAL B CG2 1 
ATOM 1580 N N   . THR B 1 86  ? 278.552 328.741 388.608 1.00 56.15  ? 85  THR B N   1 
ATOM 1581 C CA  . THR B 1 86  ? 279.426 329.529 387.748 1.00 56.15  ? 85  THR B CA  1 
ATOM 1582 C C   . THR B 1 86  ? 280.433 328.662 386.999 1.00 56.15  ? 85  THR B C   1 
ATOM 1583 O O   . THR B 1 86  ? 280.563 328.774 385.777 1.00 56.15  ? 85  THR B O   1 
ATOM 1584 C CB  . THR B 1 86  ? 280.164 330.584 388.577 1.00 56.15  ? 85  THR B CB  1 
ATOM 1585 O OG1 . THR B 1 86  ? 279.214 331.410 389.257 1.00 56.15  ? 85  THR B OG1 1 
ATOM 1586 C CG2 . THR B 1 86  ? 281.022 331.454 387.682 1.00 56.15  ? 85  THR B CG2 1 
ATOM 1587 N N   . ARG B 1 87  ? 281.144 327.794 387.714 1.00 48.60  ? 86  ARG B N   1 
ATOM 1588 C CA  . ARG B 1 87  ? 282.197 326.987 387.117 1.00 48.60  ? 86  ARG B CA  1 
ATOM 1589 C C   . ARG B 1 87  ? 282.307 325.673 387.874 1.00 48.60  ? 86  ARG B C   1 
ATOM 1590 O O   . ARG B 1 87  ? 281.793 325.524 388.984 1.00 48.60  ? 86  ARG B O   1 
ATOM 1591 C CB  . ARG B 1 87  ? 283.534 327.729 387.124 1.00 48.60  ? 86  ARG B CB  1 
ATOM 1592 C CG  . ARG B 1 87  ? 284.007 328.117 388.507 1.00 48.60  ? 86  ARG B CG  1 
ATOM 1593 C CD  . ARG B 1 87  ? 285.214 329.023 388.443 1.00 48.60  ? 86  ARG B CD  1 
ATOM 1594 N NE  . ARG B 1 87  ? 285.614 329.470 389.769 1.00 48.60  ? 86  ARG B NE  1 
ATOM 1595 C CZ  . ARG B 1 87  ? 285.227 330.611 390.321 1.00 48.60  ? 86  ARG B CZ  1 
ATOM 1596 N NH1 . ARG B 1 87  ? 284.439 331.456 389.678 1.00 48.60  ? 86  ARG B NH1 1 
ATOM 1597 N NH2 . ARG B 1 87  ? 285.638 330.909 391.549 1.00 48.60  ? 86  ARG B NH2 1 
ATOM 1598 N N   . GLN B 1 88  ? 282.989 324.715 387.254 1.00 43.82  ? 87  GLN B N   1 
ATOM 1599 C CA  . GLN B 1 88  ? 283.186 323.389 387.817 1.00 43.82  ? 87  GLN B CA  1 
ATOM 1600 C C   . GLN B 1 88  ? 284.671 323.122 388.014 1.00 43.82  ? 87  GLN B C   1 
ATOM 1601 O O   . GLN B 1 88  ? 285.518 323.682 387.313 1.00 43.82  ? 87  GLN B O   1 
ATOM 1602 C CB  . GLN B 1 88  ? 282.606 322.305 386.907 1.00 43.82  ? 87  GLN B CB  1 
ATOM 1603 C CG  . GLN B 1 88  ? 281.103 322.339 386.737 1.00 43.82  ? 87  GLN B CG  1 
ATOM 1604 C CD  . GLN B 1 88  ? 280.370 322.114 388.033 1.00 43.82  ? 87  GLN B CD  1 
ATOM 1605 O OE1 . GLN B 1 88  ? 279.761 323.028 388.577 1.00 43.82  ? 87  GLN B OE1 1 
ATOM 1606 N NE2 . GLN B 1 88  ? 280.434 320.896 388.544 1.00 43.82  ? 87  GLN B NE2 1 
ATOM 1607 N N   . ALA B 1 89  ? 284.980 322.260 388.980 1.00 37.54  ? 88  ALA B N   1 
ATOM 1608 C CA  . ALA B 1 89  ? 286.330 321.757 389.189 1.00 37.54  ? 88  ALA B CA  1 
ATOM 1609 C C   . ALA B 1 89  ? 286.265 320.247 389.327 1.00 37.54  ? 88  ALA B C   1 
ATOM 1610 O O   . ALA B 1 89  ? 285.585 319.733 390.218 1.00 37.54  ? 88  ALA B O   1 
ATOM 1611 C CB  . ALA B 1 89  ? 286.974 322.373 390.431 1.00 37.54  ? 88  ALA B CB  1 
ATOM 1612 N N   . TYR B 1 90  ? 286.978 319.540 388.458 1.00 35.33  ? 89  TYR B N   1 
ATOM 1613 C CA  . TYR B 1 90  ? 286.903 318.092 388.390 1.00 35.33  ? 89  TYR B CA  1 
ATOM 1614 C C   . TYR B 1 90  ? 288.212 317.465 388.845 1.00 35.33  ? 89  TYR B C   1 
ATOM 1615 O O   . TYR B 1 90  ? 289.242 318.131 388.962 1.00 35.33  ? 89  TYR B O   1 
ATOM 1616 C CB  . TYR B 1 90  ? 286.577 317.618 386.972 1.00 35.33  ? 89  TYR B CB  1 
ATOM 1617 C CG  . TYR B 1 90  ? 285.304 318.196 386.405 1.00 35.33  ? 89  TYR B CG  1 
ATOM 1618 C CD1 . TYR B 1 90  ? 284.068 317.682 386.761 1.00 35.33  ? 89  TYR B CD1 1 
ATOM 1619 C CD2 . TYR B 1 90  ? 285.339 319.248 385.506 1.00 35.33  ? 89  TYR B CD2 1 
ATOM 1620 C CE1 . TYR B 1 90  ? 282.905 318.201 386.243 1.00 35.33  ? 89  TYR B CE1 1 
ATOM 1621 C CE2 . TYR B 1 90  ? 284.181 319.773 384.982 1.00 35.33  ? 89  TYR B CE2 1 
ATOM 1622 C CZ  . TYR B 1 90  ? 282.966 319.246 385.355 1.00 35.33  ? 89  TYR B CZ  1 
ATOM 1623 O OH  . TYR B 1 90  ? 281.805 319.767 384.836 1.00 35.33  ? 89  TYR B OH  1 
ATOM 1624 N N   . ALA B 1 91  ? 288.147 316.161 389.101 1.00 30.93  ? 90  ALA B N   1 
ATOM 1625 C CA  . ALA B 1 91  ? 289.304 315.370 389.495 1.00 30.93  ? 90  ALA B CA  1 
ATOM 1626 C C   . ALA B 1 91  ? 288.950 313.909 389.293 1.00 30.93  ? 90  ALA B C   1 
ATOM 1627 O O   . ALA B 1 91  ? 287.887 313.467 389.733 1.00 30.93  ? 90  ALA B O   1 
ATOM 1628 C CB  . ALA B 1 91  ? 289.695 315.632 390.949 1.00 30.93  ? 90  ALA B CB  1 
ATOM 1629 N N   . ASP B 1 92  ? 289.828 313.168 388.628 1.00 33.28  ? 91  ASP B N   1 
ATOM 1630 C CA  . ASP B 1 92  ? 289.563 311.780 388.286 1.00 33.28  ? 91  ASP B CA  1 
ATOM 1631 C C   . ASP B 1 92  ? 290.783 310.935 388.605 1.00 33.28  ? 91  ASP B C   1 
ATOM 1632 O O   . ASP B 1 92  ? 291.916 311.350 388.356 1.00 33.28  ? 91  ASP B O   1 
ATOM 1633 C CB  . ASP B 1 92  ? 289.200 311.642 386.806 1.00 33.28  ? 91  ASP B CB  1 
ATOM 1634 C CG  . ASP B 1 92  ? 288.640 310.282 386.467 1.00 33.28  ? 91  ASP B CG  1 
ATOM 1635 O OD1 . ASP B 1 92  ? 288.509 309.446 387.383 1.00 33.28  ? 91  ASP B OD1 1 
ATOM 1636 O OD2 . ASP B 1 92  ? 288.333 310.044 385.281 1.00 33.28  ? 91  ASP B OD2 1 
ATOM 1637 N N   . VAL B 1 93  ? 290.545 309.752 389.163 1.00 29.23  ? 92  VAL B N   1 
ATOM 1638 C CA  . VAL B 1 93  ? 291.592 308.789 389.477 1.00 29.23  ? 92  VAL B CA  1 
ATOM 1639 C C   . VAL B 1 93  ? 291.144 307.431 388.962 1.00 29.23  ? 92  VAL B C   1 
ATOM 1640 O O   . VAL B 1 93  ? 289.948 307.127 388.963 1.00 29.23  ? 92  VAL B O   1 
ATOM 1641 C CB  . VAL B 1 93  ? 291.881 308.722 390.992 1.00 29.23  ? 92  VAL B CB  1 
ATOM 1642 C CG1 . VAL B 1 93  ? 293.152 307.949 391.257 1.00 29.23  ? 92  VAL B CG1 1 
ATOM 1643 C CG2 . VAL B 1 93  ? 291.977 310.108 391.584 1.00 29.23  ? 92  VAL B CG2 1 
ATOM 1644 N N   . THR B 1 94  ? 292.096 306.620 388.508 1.00 29.65  ? 93  THR B N   1 
ATOM 1645 C CA  . THR B 1 94  ? 291.784 305.262 388.091 1.00 29.65  ? 93  THR B CA  1 
ATOM 1646 C C   . THR B 1 94  ? 292.995 304.371 388.309 1.00 29.65  ? 93  THR B C   1 
ATOM 1647 O O   . THR B 1 94  ? 294.135 304.802 388.127 1.00 29.65  ? 93  THR B O   1 
ATOM 1648 C CB  . THR B 1 94  ? 291.332 305.206 386.627 1.00 29.65  ? 93  THR B CB  1 
ATOM 1649 O OG1 . THR B 1 94  ? 291.052 303.850 386.262 1.00 29.65  ? 93  THR B OG1 1 
ATOM 1650 C CG2 . THR B 1 94  ? 292.397 305.747 385.714 1.00 29.65  ? 93  THR B CG2 1 
ATOM 1651 N N   . PHE B 1 95  ? 292.737 303.130 388.710 1.00 30.90  ? 94  PHE B N   1 
ATOM 1652 C CA  . PHE B 1 95  ? 293.771 302.140 388.963 1.00 30.90  ? 94  PHE B CA  1 
ATOM 1653 C C   . PHE B 1 95  ? 293.497 300.904 388.120 1.00 30.90  ? 94  PHE B C   1 
ATOM 1654 O O   . PHE B 1 95  ? 292.343 300.561 387.857 1.00 30.90  ? 94  PHE B O   1 
ATOM 1655 C CB  . PHE B 1 95  ? 293.820 301.746 390.438 1.00 30.90  ? 94  PHE B CB  1 
ATOM 1656 C CG  . PHE B 1 95  ? 293.923 302.905 391.385 1.00 30.90  ? 94  PHE B CG  1 
ATOM 1657 C CD1 . PHE B 1 95  ? 292.799 303.595 391.781 1.00 30.90  ? 94  PHE B CD1 1 
ATOM 1658 C CD2 . PHE B 1 95  ? 295.147 303.282 391.904 1.00 30.90  ? 94  PHE B CD2 1 
ATOM 1659 C CE1 . PHE B 1 95  ? 292.894 304.648 392.661 1.00 30.90  ? 94  PHE B CE1 1 
ATOM 1660 C CE2 . PHE B 1 95  ? 295.246 304.333 392.786 1.00 30.90  ? 94  PHE B CE2 1 
ATOM 1661 C CZ  . PHE B 1 95  ? 294.121 305.016 393.162 1.00 30.90  ? 94  PHE B CZ  1 
ATOM 1662 N N   . SER B 1 96  ? 294.563 300.235 387.694 1.00 36.13  ? 95  SER B N   1 
ATOM 1663 C CA  . SER B 1 96  ? 294.447 299.001 386.931 1.00 36.13  ? 95  SER B CA  1 
ATOM 1664 C C   . SER B 1 96  ? 295.326 297.934 387.559 1.00 36.13  ? 95  SER B C   1 
ATOM 1665 O O   . SER B 1 96  ? 296.503 298.179 387.835 1.00 36.13  ? 95  SER B O   1 
ATOM 1666 C CB  . SER B 1 96  ? 294.838 299.212 385.469 1.00 36.13  ? 95  SER B CB  1 
ATOM 1667 O OG  . SER B 1 96  ? 293.921 300.075 384.824 1.00 36.13  ? 95  SER B OG  1 
ATOM 1668 N N   . PHE B 1 97  ? 294.756 296.753 387.776 1.00 39.85  ? 96  PHE B N   1 
ATOM 1669 C CA  . PHE B 1 97  ? 295.474 295.636 388.363 1.00 39.85  ? 96  PHE B CA  1 
ATOM 1670 C C   . PHE B 1 97  ? 295.132 294.365 387.603 1.00 39.85  ? 96  PHE B C   1 
ATOM 1671 O O   . PHE B 1 97  ? 294.056 294.249 387.014 1.00 39.85  ? 96  PHE B O   1 
ATOM 1672 C CB  . PHE B 1 97  ? 295.132 295.463 389.843 1.00 39.85  ? 96  PHE B CB  1 
ATOM 1673 C CG  . PHE B 1 97  ? 295.238 296.726 390.642 1.00 39.85  ? 96  PHE B CG  1 
ATOM 1674 C CD1 . PHE B 1 97  ? 296.468 297.306 390.886 1.00 39.85  ? 96  PHE B CD1 1 
ATOM 1675 C CD2 . PHE B 1 97  ? 294.108 297.332 391.155 1.00 39.85  ? 96  PHE B CD2 1 
ATOM 1676 C CE1 . PHE B 1 97  ? 296.566 298.465 391.626 1.00 39.85  ? 96  PHE B CE1 1 
ATOM 1677 C CE2 . PHE B 1 97  ? 294.202 298.490 391.890 1.00 39.85  ? 96  PHE B CE2 1 
ATOM 1678 C CZ  . PHE B 1 97  ? 295.433 299.057 392.126 1.00 39.85  ? 96  PHE B CZ  1 
ATOM 1679 N N   . THR B 1 98  ? 296.058 293.412 387.620 1.00 47.20  ? 97  THR B N   1 
ATOM 1680 C CA  . THR B 1 98  ? 295.839 292.127 386.979 1.00 47.20  ? 97  THR B CA  1 
ATOM 1681 C C   . THR B 1 98  ? 295.268 291.133 387.986 1.00 47.20  ? 97  THR B C   1 
ATOM 1682 O O   . THR B 1 98  ? 295.132 291.421 389.177 1.00 47.20  ? 97  THR B O   1 
ATOM 1683 C CB  . THR B 1 98  ? 297.134 291.600 386.370 1.00 47.20  ? 97  THR B CB  1 
ATOM 1684 O OG1 . THR B 1 98  ? 298.088 291.362 387.409 1.00 47.20  ? 97  THR B OG1 1 
ATOM 1685 C CG2 . THR B 1 98  ? 297.709 292.606 385.397 1.00 47.20  ? 97  THR B CG2 1 
ATOM 1686 N N   . GLN B 1 99  ? 294.931 289.938 387.501 1.00 50.38  ? 98  GLN B N   1 
ATOM 1687 C CA  . GLN B 1 99  ? 294.318 288.930 388.356 1.00 50.38  ? 98  GLN B CA  1 
ATOM 1688 C C   . GLN B 1 99  ? 295.281 288.371 389.392 1.00 50.38  ? 98  GLN B C   1 
ATOM 1689 O O   . GLN B 1 99  ? 294.829 287.787 390.381 1.00 50.38  ? 98  GLN B O   1 
ATOM 1690 C CB  . GLN B 1 99  ? 293.771 287.786 387.508 1.00 50.38  ? 98  GLN B CB  1 
ATOM 1691 C CG  . GLN B 1 99  ? 292.605 288.170 386.627 1.00 50.38  ? 98  GLN B CG  1 
ATOM 1692 C CD  . GLN B 1 99  ? 291.891 286.961 386.065 1.00 50.38  ? 98  GLN B CD  1 
ATOM 1693 O OE1 . GLN B 1 99  ? 292.370 285.833 386.178 1.00 50.38  ? 98  GLN B OE1 1 
ATOM 1694 N NE2 . GLN B 1 99  ? 290.734 287.190 385.457 1.00 50.38  ? 98  GLN B NE2 1 
ATOM 1695 N N   . TYR B 1 100 ? 296.587 288.527 389.194 1.00 49.96  ? 99  TYR B N   1 
ATOM 1696 C CA  . TYR B 1 100 ? 297.578 287.941 390.083 1.00 49.96  ? 99  TYR B CA  1 
ATOM 1697 C C   . TYR B 1 100 ? 298.270 288.967 390.968 1.00 49.96  ? 99  TYR B C   1 
ATOM 1698 O O   . TYR B 1 100 ? 299.248 288.629 391.639 1.00 49.96  ? 99  TYR B O   1 
ATOM 1699 C CB  . TYR B 1 100 ? 298.611 287.167 389.269 1.00 49.96  ? 99  TYR B CB  1 
ATOM 1700 C CG  . TYR B 1 100 ? 298.049 285.918 388.639 1.00 49.96  ? 99  TYR B CG  1 
ATOM 1701 C CD1 . TYR B 1 100 ? 297.851 284.769 389.390 1.00 49.96  ? 99  TYR B CD1 1 
ATOM 1702 C CD2 . TYR B 1 100 ? 297.709 285.889 387.297 1.00 49.96  ? 99  TYR B CD2 1 
ATOM 1703 C CE1 . TYR B 1 100 ? 297.335 283.630 388.824 1.00 49.96  ? 99  TYR B CE1 1 
ATOM 1704 C CE2 . TYR B 1 100 ? 297.191 284.751 386.721 1.00 49.96  ? 99  TYR B CE2 1 
ATOM 1705 C CZ  . TYR B 1 100 ? 297.006 283.625 387.490 1.00 49.96  ? 99  TYR B CZ  1 
ATOM 1706 O OH  . TYR B 1 100 ? 296.491 282.485 386.922 1.00 49.96  ? 99  TYR B OH  1 
ATOM 1707 N N   . SER B 1 101 ? 297.789 290.204 390.992 1.00 47.66  ? 100 SER B N   1 
ATOM 1708 C CA  . SER B 1 101 ? 298.404 291.231 391.818 1.00 47.66  ? 100 SER B CA  1 
ATOM 1709 C C   . SER B 1 101 ? 298.156 290.949 393.294 1.00 47.66  ? 100 SER B C   1 
ATOM 1710 O O   . SER B 1 101 ? 297.028 290.662 393.700 1.00 47.66  ? 100 SER B O   1 
ATOM 1711 C CB  . SER B 1 101 ? 297.852 292.601 391.449 1.00 47.66  ? 100 SER B CB  1 
ATOM 1712 O OG  . SER B 1 101 ? 296.440 292.607 391.540 1.00 47.66  ? 100 SER B OG  1 
ATOM 1713 N N   . THR B 1 102 ? 299.209 291.041 394.096 1.00 49.53  ? 101 THR B N   1 
ATOM 1714 C CA  . THR B 1 102 ? 299.092 290.868 395.534 1.00 49.53  ? 101 THR B CA  1 
ATOM 1715 C C   . THR B 1 102 ? 298.725 292.188 396.200 1.00 49.53  ? 101 THR B C   1 
ATOM 1716 O O   . THR B 1 102 ? 298.994 293.270 395.678 1.00 49.53  ? 101 THR B O   1 
ATOM 1717 C CB  . THR B 1 102 ? 300.392 290.328 396.121 1.00 49.53  ? 101 THR B CB  1 
ATOM 1718 O OG1 . THR B 1 102 ? 301.444 291.270 395.897 1.00 49.53  ? 101 THR B OG1 1 
ATOM 1719 C CG2 . THR B 1 102 ? 300.759 289.014 395.463 1.00 49.53  ? 101 THR B CG2 1 
ATOM 1720 N N   . ASP B 1 103 ? 298.104 292.082 397.377 1.00 54.00  ? 102 ASP B N   1 
ATOM 1721 C CA  . ASP B 1 103 ? 297.588 293.265 398.059 1.00 54.00  ? 102 ASP B CA  1 
ATOM 1722 C C   . ASP B 1 103 ? 298.697 294.234 398.442 1.00 54.00  ? 102 ASP B C   1 
ATOM 1723 O O   . ASP B 1 103 ? 298.447 295.437 398.583 1.00 54.00  ? 102 ASP B O   1 
ATOM 1724 C CB  . ASP B 1 103 ? 296.800 292.849 399.299 1.00 54.00  ? 102 ASP B CB  1 
ATOM 1725 C CG  . ASP B 1 103 ? 297.514 291.791 400.111 1.00 54.00  ? 102 ASP B CG  1 
ATOM 1726 O OD1 . ASP B 1 103 ? 298.312 291.032 399.524 1.00 54.00  ? 102 ASP B OD1 1 
ATOM 1727 O OD2 . ASP B 1 103 ? 297.278 291.716 401.335 1.00 54.00  ? 102 ASP B OD2 1 
ATOM 1728 N N   . GLU B 1 104 ? 299.923 293.737 398.613 1.00 54.77  ? 103 GLU B N   1 
ATOM 1729 C CA  . GLU B 1 104 ? 301.036 294.619 398.942 1.00 54.77  ? 103 GLU B CA  1 
ATOM 1730 C C   . GLU B 1 104 ? 301.294 295.619 397.824 1.00 54.77  ? 103 GLU B C   1 
ATOM 1731 O O   . GLU B 1 104 ? 301.525 296.805 398.084 1.00 54.77  ? 103 GLU B O   1 
ATOM 1732 C CB  . GLU B 1 104 ? 302.290 293.796 399.224 1.00 54.77  ? 103 GLU B CB  1 
ATOM 1733 C CG  . GLU B 1 104 ? 302.016 292.488 399.936 1.00 54.77  ? 103 GLU B CG  1 
ATOM 1734 C CD  . GLU B 1 104 ? 301.683 292.683 401.401 1.00 54.77  ? 103 GLU B CD  1 
ATOM 1735 O OE1 . GLU B 1 104 ? 302.053 293.736 401.960 1.00 54.77  ? 103 GLU B OE1 1 
ATOM 1736 O OE2 . GLU B 1 104 ? 301.052 291.782 401.993 1.00 54.77  ? 103 GLU B OE2 1 
ATOM 1737 N N   . GLU B 1 105 ? 301.251 295.163 396.571 1.00 51.32  ? 104 GLU B N   1 
ATOM 1738 C CA  . GLU B 1 105 ? 301.477 296.063 395.446 1.00 51.32  ? 104 GLU B CA  1 
ATOM 1739 C C   . GLU B 1 105 ? 300.385 297.121 395.353 1.00 51.32  ? 104 GLU B C   1 
ATOM 1740 O O   . GLU B 1 105 ? 300.669 298.300 395.102 1.00 51.32  ? 104 GLU B O   1 
ATOM 1741 C CB  . GLU B 1 105 ? 301.557 295.260 394.152 1.00 51.32  ? 104 GLU B CB  1 
ATOM 1742 C CG  . GLU B 1 105 ? 302.369 293.987 394.277 1.00 51.32  ? 104 GLU B CG  1 
ATOM 1743 C CD  . GLU B 1 105 ? 302.350 293.159 393.009 1.00 51.32  ? 104 GLU B CD  1 
ATOM 1744 O OE1 . GLU B 1 105 ? 301.858 293.662 391.978 1.00 51.32  ? 104 GLU B OE1 1 
ATOM 1745 O OE2 . GLU B 1 105 ? 302.827 292.006 393.043 1.00 51.32  ? 104 GLU B OE2 1 
ATOM 1746 N N   . ARG B 1 106 ? 299.128 296.721 395.545 1.00 46.03  ? 105 ARG B N   1 
ATOM 1747 C CA  . ARG B 1 106 ? 298.027 297.674 395.478 1.00 46.03  ? 105 ARG B CA  1 
ATOM 1748 C C   . ARG B 1 106 ? 298.123 298.706 396.594 1.00 46.03  ? 105 ARG B C   1 
ATOM 1749 O O   . ARG B 1 106 ? 297.917 299.907 396.365 1.00 46.03  ? 105 ARG B O   1 
ATOM 1750 C CB  . ARG B 1 106 ? 296.699 296.922 395.531 1.00 46.03  ? 105 ARG B CB  1 
ATOM 1751 C CG  . ARG B 1 106 ? 296.541 295.913 394.404 1.00 46.03  ? 105 ARG B CG  1 
ATOM 1752 C CD  . ARG B 1 106 ? 295.176 295.257 394.409 1.00 46.03  ? 105 ARG B CD  1 
ATOM 1753 N NE  . ARG B 1 106 ? 294.974 294.406 395.574 1.00 46.03  ? 105 ARG B NE  1 
ATOM 1754 C CZ  . ARG B 1 106 ? 294.948 293.082 395.534 1.00 46.03  ? 105 ARG B CZ  1 
ATOM 1755 N NH1 . ARG B 1 106 ? 295.132 292.423 394.405 1.00 46.03  ? 105 ARG B NH1 1 
ATOM 1756 N NH2 . ARG B 1 106 ? 294.726 292.403 396.655 1.00 46.03  ? 105 ARG B NH2 1 
ATOM 1757 N N   . ALA B 1 107 ? 298.453 298.262 397.807 1.00 45.10  ? 106 ALA B N   1 
ATOM 1758 C CA  . ALA B 1 107 ? 298.641 299.202 398.905 1.00 45.10  ? 106 ALA B CA  1 
ATOM 1759 C C   . ALA B 1 107 ? 299.803 300.144 398.629 1.00 45.10  ? 106 ALA B C   1 
ATOM 1760 O O   . ALA B 1 107 ? 299.732 301.337 398.944 1.00 45.10  ? 106 ALA B O   1 
ATOM 1761 C CB  . ALA B 1 107 ? 298.864 298.448 400.212 1.00 45.10  ? 106 ALA B CB  1 
ATOM 1762 N N   . PHE B 1 108 ? 300.888 299.625 398.051 1.00 45.12  ? 107 PHE B N   1 
ATOM 1763 C CA  . PHE B 1 108 ? 302.026 300.478 397.730 1.00 45.12  ? 107 PHE B CA  1 
ATOM 1764 C C   . PHE B 1 108 ? 301.640 301.547 396.722 1.00 45.12  ? 107 PHE B C   1 
ATOM 1765 O O   . PHE B 1 108 ? 302.019 302.711 396.872 1.00 45.12  ? 107 PHE B O   1 
ATOM 1766 C CB  . PHE B 1 108 ? 303.183 299.634 397.198 1.00 45.12  ? 107 PHE B CB  1 
ATOM 1767 C CG  . PHE B 1 108 ? 304.470 300.391 397.068 1.00 45.12  ? 107 PHE B CG  1 
ATOM 1768 C CD1 . PHE B 1 108 ? 305.325 300.513 398.146 1.00 45.12  ? 107 PHE B CD1 1 
ATOM 1769 C CD2 . PHE B 1 108 ? 304.826 300.978 395.870 1.00 45.12  ? 107 PHE B CD2 1 
ATOM 1770 C CE1 . PHE B 1 108 ? 306.508 301.208 398.032 1.00 45.12  ? 107 PHE B CE1 1 
ATOM 1771 C CE2 . PHE B 1 108 ? 306.009 301.675 395.751 1.00 45.12  ? 107 PHE B CE2 1 
ATOM 1772 C CZ  . PHE B 1 108 ? 306.849 301.789 396.833 1.00 45.12  ? 107 PHE B CZ  1 
ATOM 1773 N N   . VAL B 1 109 ? 300.875 301.173 395.696 1.00 41.01  ? 108 VAL B N   1 
ATOM 1774 C CA  . VAL B 1 109 ? 300.443 302.153 394.701 1.00 41.01  ? 108 VAL B CA  1 
ATOM 1775 C C   . VAL B 1 109 ? 299.576 303.224 395.352 1.00 41.01  ? 108 VAL B C   1 
ATOM 1776 O O   . VAL B 1 109 ? 299.755 304.427 395.115 1.00 41.01  ? 108 VAL B O   1 
ATOM 1777 C CB  . VAL B 1 109 ? 299.702 301.459 393.546 1.00 41.01  ? 108 VAL B CB  1 
ATOM 1778 C CG1 . VAL B 1 109 ? 299.069 302.487 392.641 1.00 41.01  ? 108 VAL B CG1 1 
ATOM 1779 C CG2 . VAL B 1 109 ? 300.652 300.583 392.763 1.00 41.01  ? 108 VAL B CG2 1 
ATOM 1780 N N   . ARG B 1 110 ? 298.629 302.804 396.195 1.00 40.57  ? 109 ARG B N   1 
ATOM 1781 C CA  . ARG B 1 110 ? 297.731 303.768 396.824 1.00 40.57  ? 109 ARG B CA  1 
ATOM 1782 C C   . ARG B 1 110 ? 298.495 304.734 397.722 1.00 40.57  ? 109 ARG B C   1 
ATOM 1783 O O   . ARG B 1 110 ? 298.284 305.951 397.666 1.00 40.57  ? 109 ARG B O   1 
ATOM 1784 C CB  . ARG B 1 110 ? 296.649 303.040 397.618 1.00 40.57  ? 109 ARG B CB  1 
ATOM 1785 C CG  . ARG B 1 110 ? 295.810 303.959 398.480 1.00 40.57  ? 109 ARG B CG  1 
ATOM 1786 C CD  . ARG B 1 110 ? 294.790 303.192 399.290 1.00 40.57  ? 109 ARG B CD  1 
ATOM 1787 N NE  . ARG B 1 110 ? 295.417 302.311 400.264 1.00 40.57  ? 109 ARG B NE  1 
ATOM 1788 C CZ  . ARG B 1 110 ? 295.940 302.716 401.412 1.00 40.57  ? 109 ARG B CZ  1 
ATOM 1789 N NH1 . ARG B 1 110 ? 295.923 303.989 401.768 1.00 40.57  ? 109 ARG B NH1 1 
ATOM 1790 N NH2 . ARG B 1 110 ? 296.493 301.821 402.225 1.00 40.57  ? 109 ARG B NH2 1 
ATOM 1791 N N   . THR B 1 111 ? 299.401 304.212 398.550 1.00 41.64  ? 110 THR B N   1 
ATOM 1792 C CA  . THR B 1 111 ? 300.140 305.076 399.466 1.00 41.64  ? 110 THR B CA  1 
ATOM 1793 C C   . THR B 1 111 ? 301.116 305.980 398.723 1.00 41.64  ? 110 THR B C   1 
ATOM 1794 O O   . THR B 1 111 ? 301.320 307.133 399.117 1.00 41.64  ? 110 THR B O   1 
ATOM 1795 C CB  . THR B 1 111 ? 300.873 304.240 400.511 1.00 41.64  ? 110 THR B CB  1 
ATOM 1796 O OG1 . THR B 1 111 ? 301.813 303.376 399.861 1.00 41.64  ? 110 THR B OG1 1 
ATOM 1797 C CG2 . THR B 1 111 ? 299.894 303.415 401.320 1.00 41.64  ? 110 THR B CG2 1 
ATOM 1798 N N   . GLU B 1 112 ? 301.737 305.479 397.653 1.00 41.23  ? 111 GLU B N   1 
ATOM 1799 C CA  . GLU B 1 112 ? 302.623 306.320 396.860 1.00 41.23  ? 111 GLU B CA  1 
ATOM 1800 C C   . GLU B 1 112 ? 301.860 307.470 396.221 1.00 41.23  ? 111 GLU B C   1 
ATOM 1801 O O   . GLU B 1 112 ? 302.334 308.613 396.216 1.00 41.23  ? 111 GLU B O   1 
ATOM 1802 C CB  . GLU B 1 112 ? 303.321 305.479 395.795 1.00 41.23  ? 111 GLU B CB  1 
ATOM 1803 C CG  . GLU B 1 112 ? 303.960 306.284 394.689 1.00 41.23  ? 111 GLU B CG  1 
ATOM 1804 C CD  . GLU B 1 112 ? 304.689 305.416 393.690 1.00 41.23  ? 111 GLU B CD  1 
ATOM 1805 O OE1 . GLU B 1 112 ? 304.651 304.178 393.841 1.00 41.23  ? 111 GLU B OE1 1 
ATOM 1806 O OE2 . GLU B 1 112 ? 305.303 305.968 392.754 1.00 41.23  ? 111 GLU B OE2 1 
ATOM 1807 N N   . LEU B 1 113 ? 300.672 307.192 395.682 1.00 38.44  ? 112 LEU B N   1 
ATOM 1808 C CA  . LEU B 1 113 ? 299.867 308.264 395.110 1.00 38.44  ? 112 LEU B CA  1 
ATOM 1809 C C   . LEU B 1 113 ? 299.428 309.255 396.178 1.00 38.44  ? 112 LEU B C   1 
ATOM 1810 O O   . LEU B 1 113 ? 299.370 310.463 395.927 1.00 38.44  ? 112 LEU B O   1 
ATOM 1811 C CB  . LEU B 1 113 ? 298.656 307.689 394.384 1.00 38.44  ? 112 LEU B CB  1 
ATOM 1812 C CG  . LEU B 1 113 ? 297.772 308.733 393.708 1.00 38.44  ? 112 LEU B CG  1 
ATOM 1813 C CD1 . LEU B 1 113 ? 298.591 309.572 392.754 1.00 38.44  ? 112 LEU B CD1 1 
ATOM 1814 C CD2 . LEU B 1 113 ? 296.627 308.069 392.979 1.00 38.44  ? 112 LEU B CD2 1 
ATOM 1815 N N   . ALA B 1 114 ? 299.102 308.765 397.374 1.00 39.64  ? 113 ALA B N   1 
ATOM 1816 C CA  . ALA B 1 114 ? 298.711 309.670 398.450 1.00 39.64  ? 113 ALA B CA  1 
ATOM 1817 C C   . ALA B 1 114 ? 299.867 310.568 398.870 1.00 39.64  ? 113 ALA B C   1 
ATOM 1818 O O   . ALA B 1 114 ? 299.666 311.751 399.161 1.00 39.64  ? 113 ALA B O   1 
ATOM 1819 C CB  . ALA B 1 114 ? 298.189 308.875 399.644 1.00 39.64  ? 113 ALA B CB  1 
ATOM 1820 N N   . ALA B 1 115 ? 301.082 310.021 398.921 1.00 39.99  ? 114 ALA B N   1 
ATOM 1821 C CA  . ALA B 1 115 ? 302.236 310.792 399.370 1.00 39.99  ? 114 ALA B CA  1 
ATOM 1822 C C   . ALA B 1 115 ? 302.753 311.750 398.305 1.00 39.99  ? 114 ALA B C   1 
ATOM 1823 O O   . ALA B 1 115 ? 303.336 312.783 398.645 1.00 39.99  ? 114 ALA B O   1 
ATOM 1824 C CB  . ALA B 1 115 ? 303.356 309.851 399.811 1.00 39.99  ? 114 ALA B CB  1 
ATOM 1825 N N   . LEU B 1 116 ? 302.569 311.428 397.022 1.00 39.64  ? 115 LEU B N   1 
ATOM 1826 C CA  . LEU B 1 116 ? 303.019 312.333 395.969 1.00 39.64  ? 115 LEU B CA  1 
ATOM 1827 C C   . LEU B 1 116 ? 302.275 313.661 396.017 1.00 39.64  ? 115 LEU B C   1 
ATOM 1828 O O   . LEU B 1 116 ? 302.863 314.718 395.761 1.00 39.64  ? 115 LEU B O   1 
ATOM 1829 C CB  . LEU B 1 116 ? 302.838 311.686 394.599 1.00 39.64  ? 115 LEU B CB  1 
ATOM 1830 C CG  . LEU B 1 116 ? 303.959 310.784 394.102 1.00 39.64  ? 115 LEU B CG  1 
ATOM 1831 C CD1 . LEU B 1 116 ? 303.549 310.127 392.803 1.00 39.64  ? 115 LEU B CD1 1 
ATOM 1832 C CD2 . LEU B 1 116 ? 305.225 311.587 393.916 1.00 39.64  ? 115 LEU B CD2 1 
ATOM 1833 N N   . LEU B 1 117 ? 300.981 313.628 396.337 1.00 39.44  ? 116 LEU B N   1 
ATOM 1834 C CA  . LEU B 1 117 ? 300.167 314.836 396.299 1.00 39.44  ? 116 LEU B CA  1 
ATOM 1835 C C   . LEU B 1 117 ? 300.574 315.857 397.352 1.00 39.44  ? 116 LEU B C   1 
ATOM 1836 O O   . LEU B 1 117 ? 300.160 317.016 397.260 1.00 39.44  ? 116 LEU B O   1 
ATOM 1837 C CB  . LEU B 1 117 ? 298.693 314.475 396.473 1.00 39.44  ? 116 LEU B CB  1 
ATOM 1838 C CG  . LEU B 1 117 ? 298.045 313.692 395.333 1.00 39.44  ? 116 LEU B CG  1 
ATOM 1839 C CD1 . LEU B 1 117 ? 296.703 313.142 395.762 1.00 39.44  ? 116 LEU B CD1 1 
ATOM 1840 C CD2 . LEU B 1 117 ? 297.891 314.563 394.107 1.00 39.44  ? 116 LEU B CD2 1 
ATOM 1841 N N   . ALA B 1 118 ? 301.361 315.460 398.349 1.00 39.96  ? 117 ALA B N   1 
ATOM 1842 C CA  . ALA B 1 118 ? 301.817 316.374 399.387 1.00 39.96  ? 117 ALA B CA  1 
ATOM 1843 C C   . ALA B 1 118 ? 303.233 316.886 399.162 1.00 39.96  ? 117 ALA B C   1 
ATOM 1844 O O   . ALA B 1 118 ? 303.721 317.676 399.973 1.00 39.96  ? 117 ALA B O   1 
ATOM 1845 C CB  . ALA B 1 118 ? 301.738 315.697 400.759 1.00 39.96  ? 117 ALA B CB  1 
ATOM 1846 N N   . SER B 1 119 ? 303.897 316.458 398.096 1.00 40.89  ? 118 SER B N   1 
ATOM 1847 C CA  . SER B 1 119 ? 305.256 316.881 397.810 1.00 40.89  ? 118 SER B CA  1 
ATOM 1848 C C   . SER B 1 119 ? 305.265 318.266 397.174 1.00 40.89  ? 118 SER B C   1 
ATOM 1849 O O   . SER B 1 119 ? 304.260 318.709 396.618 1.00 40.89  ? 118 SER B O   1 
ATOM 1850 C CB  . SER B 1 119 ? 305.931 315.872 396.890 1.00 40.89  ? 118 SER B CB  1 
ATOM 1851 O OG  . SER B 1 119 ? 305.436 315.983 395.570 1.00 40.89  ? 118 SER B OG  1 
ATOM 1852 N N   . PRO B 1 120 ? 306.391 318.980 397.258 1.00 43.78  ? 119 PRO B N   1 
ATOM 1853 C CA  . PRO B 1 120 ? 306.452 320.318 396.648 1.00 43.78  ? 119 PRO B CA  1 
ATOM 1854 C C   . PRO B 1 120 ? 306.178 320.326 395.157 1.00 43.78  ? 119 PRO B C   1 
ATOM 1855 O O   . PRO B 1 120 ? 305.617 321.303 394.645 1.00 43.78  ? 119 PRO B O   1 
ATOM 1856 C CB  . PRO B 1 120 ? 307.884 320.771 396.960 1.00 43.78  ? 119 PRO B CB  1 
ATOM 1857 C CG  . PRO B 1 120 ? 308.242 320.029 398.190 1.00 43.78  ? 119 PRO B CG  1 
ATOM 1858 C CD  . PRO B 1 120 ? 307.595 318.688 398.052 1.00 43.78  ? 119 PRO B CD  1 
ATOM 1859 N N   . LEU B 1 121 ? 306.557 319.264 394.444 1.00 42.99  ? 120 LEU B N   1 
ATOM 1860 C CA  . LEU B 1 121 ? 306.349 319.222 393.001 1.00 42.99  ? 120 LEU B CA  1 
ATOM 1861 C C   . LEU B 1 121 ? 304.871 319.327 392.648 1.00 42.99  ? 120 LEU B C   1 
ATOM 1862 O O   . LEU B 1 121 ? 304.472 320.191 391.858 1.00 42.99  ? 120 LEU B O   1 
ATOM 1863 C CB  . LEU B 1 121 ? 306.943 317.933 392.437 1.00 42.99  ? 120 LEU B CB  1 
ATOM 1864 C CG  . LEU B 1 121 ? 306.798 317.657 390.943 1.00 42.99  ? 120 LEU B CG  1 
ATOM 1865 C CD1 . LEU B 1 121 ? 307.628 318.633 390.131 1.00 42.99  ? 120 LEU B CD1 1 
ATOM 1866 C CD2 . LEU B 1 121 ? 307.199 316.227 390.637 1.00 42.99  ? 120 LEU B CD2 1 
ATOM 1867 N N   . LEU B 1 122 ? 304.040 318.470 393.239 1.00 41.41  ? 121 LEU B N   1 
ATOM 1868 C CA  . LEU B 1 122 ? 302.610 318.506 392.960 1.00 41.41  ? 121 LEU B CA  1 
ATOM 1869 C C   . LEU B 1 122 ? 301.945 319.744 393.539 1.00 41.41  ? 121 LEU B C   1 
ATOM 1870 O O   . LEU B 1 122 ? 301.022 320.288 392.922 1.00 41.41  ? 121 LEU B O   1 
ATOM 1871 C CB  . LEU B 1 122 ? 301.930 317.249 393.500 1.00 41.41  ? 121 LEU B CB  1 
ATOM 1872 C CG  . LEU B 1 122 ? 301.947 315.994 392.627 1.00 41.41  ? 121 LEU B CG  1 
ATOM 1873 C CD1 . LEU B 1 122 ? 301.182 316.257 391.353 1.00 41.41  ? 121 LEU B CD1 1 
ATOM 1874 C CD2 . LEU B 1 122 ? 303.355 315.521 392.317 1.00 41.41  ? 121 LEU B CD2 1 
ATOM 1875 N N   . ILE B 1 123 ? 302.395 320.204 394.706 1.00 42.67  ? 122 ILE B N   1 
ATOM 1876 C CA  . ILE B 1 123 ? 301.838 321.423 395.284 1.00 42.67  ? 122 ILE B CA  1 
ATOM 1877 C C   . ILE B 1 123 ? 302.030 322.594 394.335 1.00 42.67  ? 122 ILE B C   1 
ATOM 1878 O O   . ILE B 1 123 ? 301.127 323.415 394.149 1.00 42.67  ? 122 ILE B O   1 
ATOM 1879 C CB  . ILE B 1 123 ? 302.464 321.707 396.661 1.00 42.67  ? 122 ILE B CB  1 
ATOM 1880 C CG1 . ILE B 1 123 ? 301.934 320.730 397.702 1.00 42.67  ? 122 ILE B CG1 1 
ATOM 1881 C CG2 . ILE B 1 123 ? 302.159 323.119 397.101 1.00 42.67  ? 122 ILE B CG2 1 
ATOM 1882 C CD1 . ILE B 1 123 ? 302.542 320.923 399.063 1.00 42.67  ? 122 ILE B CD1 1 
ATOM 1883 N N   . ASP B 1 124 ? 303.204 322.690 393.714 1.00 45.94  ? 123 ASP B N   1 
ATOM 1884 C CA  . ASP B 1 124 ? 303.438 323.804 392.805 1.00 45.94  ? 123 ASP B CA  1 
ATOM 1885 C C   . ASP B 1 124 ? 302.731 323.583 391.472 1.00 45.94  ? 123 ASP B C   1 
ATOM 1886 O O   . ASP B 1 124 ? 302.227 324.535 390.868 1.00 45.94  ? 123 ASP B O   1 
ATOM 1887 C CB  . ASP B 1 124 ? 304.937 324.010 392.601 1.00 45.94  ? 123 ASP B CB  1 
ATOM 1888 C CG  . ASP B 1 124 ? 305.261 325.335 391.936 1.00 45.94  ? 123 ASP B CG  1 
ATOM 1889 O OD1 . ASP B 1 124 ? 304.324 326.083 391.594 1.00 45.94  ? 123 ASP B OD1 1 
ATOM 1890 O OD2 . ASP B 1 124 ? 306.457 325.642 391.768 1.00 45.94  ? 123 ASP B OD2 1 
ATOM 1891 N N   . ALA B 1 125 ? 302.666 322.335 391.002 1.00 43.00  ? 124 ALA B N   1 
ATOM 1892 C CA  . ALA B 1 125 ? 302.066 322.082 389.696 1.00 43.00  ? 124 ALA B CA  1 
ATOM 1893 C C   . ALA B 1 125 ? 300.555 322.272 389.705 1.00 43.00  ? 124 ALA B C   1 
ATOM 1894 O O   . ALA B 1 125 ? 299.984 322.681 388.690 1.00 43.00  ? 124 ALA B O   1 
ATOM 1895 C CB  . ALA B 1 125 ? 302.412 320.674 389.218 1.00 43.00  ? 124 ALA B CB  1 
ATOM 1896 N N   . ILE B 1 126 ? 299.887 321.973 390.815 1.00 42.51  ? 125 ILE B N   1 
ATOM 1897 C CA  . ILE B 1 126 ? 298.428 322.044 390.849 1.00 42.51  ? 125 ILE B CA  1 
ATOM 1898 C C   . ILE B 1 126 ? 297.945 323.387 391.376 1.00 42.51  ? 125 ILE B C   1 
ATOM 1899 O O   . ILE B 1 126 ? 297.094 324.034 390.762 1.00 42.51  ? 125 ILE B O   1 
ATOM 1900 C CB  . ILE B 1 126 ? 297.854 320.880 391.681 1.00 42.51  ? 125 ILE B CB  1 
ATOM 1901 C CG1 . ILE B 1 126 ? 298.202 319.541 391.037 1.00 42.51  ? 125 ILE B CG1 1 
ATOM 1902 C CG2 . ILE B 1 126 ? 296.354 321.013 391.806 1.00 42.51  ? 125 ILE B CG2 1 
ATOM 1903 C CD1 . ILE B 1 126 ? 297.997 318.365 391.951 1.00 42.51  ? 125 ILE B CD1 1 
ATOM 1904 N N   . ASP B 1 127 ? 298.466 323.826 392.521 1.00 46.42  ? 126 ASP B N   1 
ATOM 1905 C CA  . ASP B 1 127 ? 297.979 325.062 393.123 1.00 46.42  ? 126 ASP B CA  1 
ATOM 1906 C C   . ASP B 1 127 ? 298.331 326.272 392.269 1.00 46.42  ? 126 ASP B C   1 
ATOM 1907 O O   . ASP B 1 127 ? 297.464 327.090 391.945 1.00 46.42  ? 126 ASP B O   1 
ATOM 1908 C CB  . ASP B 1 127 ? 298.552 325.221 394.528 1.00 46.42  ? 126 ASP B CB  1 
ATOM 1909 C CG  . ASP B 1 127 ? 298.002 324.203 395.490 1.00 46.42  ? 126 ASP B CG  1 
ATOM 1910 O OD1 . ASP B 1 127 ? 296.857 323.765 395.285 1.00 46.42  ? 126 ASP B OD1 1 
ATOM 1911 O OD2 . ASP B 1 127 ? 298.706 323.845 396.455 1.00 46.42  ? 126 ASP B OD2 1 
ATOM 1912 N N   . GLN B 1 128 ? 299.599 326.401 391.889 1.00 48.17  ? 127 GLN B N   1 
ATOM 1913 C CA  . GLN B 1 128 ? 300.080 327.561 391.153 1.00 48.17  ? 127 GLN B CA  1 
ATOM 1914 C C   . GLN B 1 128 ? 300.100 327.350 389.648 1.00 48.17  ? 127 GLN B C   1 
ATOM 1915 O O   . GLN B 1 128 ? 300.450 328.278 388.915 1.00 48.17  ? 127 GLN B O   1 
ATOM 1916 C CB  . GLN B 1 128 ? 301.479 327.945 391.636 1.00 48.17  ? 127 GLN B CB  1 
ATOM 1917 C CG  . GLN B 1 128 ? 301.599 328.038 393.142 1.00 48.17  ? 127 GLN B CG  1 
ATOM 1918 C CD  . GLN B 1 128 ? 300.663 329.072 393.732 1.00 48.17  ? 127 GLN B CD  1 
ATOM 1919 O OE1 . GLN B 1 128 ? 300.393 330.104 393.119 1.00 48.17  ? 127 GLN B OE1 1 
ATOM 1920 N NE2 . GLN B 1 128 ? 300.159 328.799 394.928 1.00 48.17  ? 127 GLN B NE2 1 
ATOM 1921 N N   . LEU B 1 129 ? 299.741 326.157 389.177 1.00 44.61  ? 128 LEU B N   1 
ATOM 1922 C CA  . LEU B 1 129 ? 299.693 325.846 387.749 1.00 44.61  ? 128 LEU B CA  1 
ATOM 1923 C C   . LEU B 1 129 ? 301.043 326.070 387.073 1.00 44.61  ? 128 LEU B C   1 
ATOM 1924 O O   . LEU B 1 129 ? 301.109 326.401 385.888 1.00 44.61  ? 128 LEU B O   1 
ATOM 1925 C CB  . LEU B 1 129 ? 298.597 326.651 387.051 1.00 44.61  ? 128 LEU B CB  1 
ATOM 1926 C CG  . LEU B 1 129 ? 297.196 326.392 387.600 1.00 44.61  ? 128 LEU B CG  1 
ATOM 1927 C CD1 . LEU B 1 129 ? 296.163 327.180 386.832 1.00 44.61  ? 128 LEU B CD1 1 
ATOM 1928 C CD2 . LEU B 1 129 ? 296.882 324.913 387.539 1.00 44.61  ? 128 LEU B CD2 1 
ATOM 1929 N N   . ASN B 1 130 ? 302.125 325.881 387.824 1.00 47.87  ? 129 ASN B N   1 
ATOM 1930 C CA  . ASN B 1 130 ? 303.471 326.034 387.293 1.00 47.87  ? 129 ASN B CA  1 
ATOM 1931 C C   . ASN B 1 130 ? 303.952 324.705 386.733 1.00 47.87  ? 129 ASN B C   1 
ATOM 1932 O O   . ASN B 1 130 ? 304.078 323.739 387.495 1.00 47.87  ? 129 ASN B O   1 
ATOM 1933 C CB  . ASN B 1 130 ? 304.423 326.501 388.376 1.00 47.87  ? 129 ASN B CB  1 
ATOM 1934 C CG  . ASN B 1 130 ? 304.654 327.989 388.343 1.00 47.87  ? 129 ASN B CG  1 
ATOM 1935 O OD1 . ASN B 1 130 ? 304.728 328.591 387.275 1.00 47.87  ? 129 ASN B OD1 1 
ATOM 1936 N ND2 . ASN B 1 130 ? 304.768 328.595 389.516 1.00 47.87  ? 129 ASN B ND2 1 
ATOM 1937 N N   . PRO B 1 131 ? 304.240 324.606 385.439 1.00 48.59  ? 130 PRO B N   1 
ATOM 1938 C CA  . PRO B 1 131 ? 304.727 323.336 384.899 1.00 48.59  ? 130 PRO B CA  1 
ATOM 1939 C C   . PRO B 1 131 ? 306.106 323.010 385.440 1.00 48.59  ? 130 PRO B C   1 
ATOM 1940 O O   . PRO B 1 131 ? 306.917 323.896 385.716 1.00 48.59  ? 130 PRO B O   1 
ATOM 1941 C CB  . PRO B 1 131 ? 304.760 323.573 383.384 1.00 48.59  ? 130 PRO B CB  1 
ATOM 1942 C CG  . PRO B 1 131 ? 304.611 325.040 383.185 1.00 48.59  ? 130 PRO B CG  1 
ATOM 1943 C CD  . PRO B 1 131 ? 304.412 325.721 384.497 1.00 48.59  ? 130 PRO B CD  1 
ATOM 1944 N N   . ALA B 1 132 ? 306.365 321.715 385.601 1.00 52.65  ? 131 ALA B N   1 
ATOM 1945 C CA  . ALA B 1 132 ? 307.639 321.273 386.150 1.00 52.65  ? 131 ALA B CA  1 
ATOM 1946 C C   . ALA B 1 132 ? 308.760 321.543 385.157 1.00 52.65  ? 131 ALA B C   1 
ATOM 1947 O O   . ALA B 1 132 ? 308.690 321.128 383.997 1.00 52.65  ? 131 ALA B O   1 
ATOM 1948 C CB  . ALA B 1 132 ? 307.580 319.788 386.498 1.00 52.65  ? 131 ALA B CB  1 
ATOM 1949 N N   . TYR B 1 133 ? 309.798 322.232 385.616 1.00 56.33  ? 132 TYR B N   1 
ATOM 1950 C CA  . TYR B 1 133 ? 310.904 322.612 384.749 1.00 56.33  ? 132 TYR B CA  1 
ATOM 1951 C C   . TYR B 1 133 ? 312.177 322.867 385.548 1.00 56.33  ? 132 TYR B C   1 
ATOM 1952 O O   . TYR B 1 133 ? 313.236 322.320 385.245 1.00 56.33  ? 132 TYR B O   1 
ATOM 1953 C CB  . TYR B 1 133 ? 310.537 323.855 383.937 1.00 56.33  ? 132 TYR B CB  1 
ATOM 1954 C CG  . TYR B 1 133 ? 311.625 324.317 383.000 1.00 56.33  ? 132 TYR B CG  1 
ATOM 1955 C CD1 . TYR B 1 133 ? 311.838 323.680 381.786 1.00 56.33  ? 132 TYR B CD1 1 
ATOM 1956 C CD2 . TYR B 1 133 ? 312.441 325.391 383.330 1.00 56.33  ? 132 TYR B CD2 1 
ATOM 1957 C CE1 . TYR B 1 133 ? 312.834 324.097 380.927 1.00 56.33  ? 132 TYR B CE1 1 
ATOM 1958 C CE2 . TYR B 1 133 ? 313.438 325.817 382.479 1.00 56.33  ? 132 TYR B CE2 1 
ATOM 1959 C CZ  . TYR B 1 133 ? 313.632 325.166 381.279 1.00 56.33  ? 132 TYR B CZ  1 
ATOM 1960 O OH  . TYR B 1 133 ? 314.627 325.588 380.428 1.00 56.33  ? 132 TYR B OH  1 
ATOM 1961 O OXT . TYR B 1 133 ? 312.177 323.626 386.515 1.00 56.33  ? 132 TYR B OXT 1 
ATOM 1962 N N   . VAL C 2 5   ? 318.945 305.742 418.946 1.00 79.05  ? 5   VAL H N   1 
ATOM 1963 C CA  . VAL C 2 5   ? 319.388 306.296 417.674 1.00 79.05  ? 5   VAL H CA  1 
ATOM 1964 C C   . VAL C 2 5   ? 320.336 307.463 417.905 1.00 79.05  ? 5   VAL H C   1 
ATOM 1965 O O   . VAL C 2 5   ? 319.918 308.542 418.318 1.00 79.05  ? 5   VAL H O   1 
ATOM 1966 C CB  . VAL C 2 5   ? 318.196 306.737 416.815 1.00 79.05  ? 5   VAL H CB  1 
ATOM 1967 C CG1 . VAL C 2 5   ? 318.683 307.362 415.518 1.00 79.05  ? 5   VAL H CG1 1 
ATOM 1968 C CG2 . VAL C 2 5   ? 317.284 305.558 416.534 1.00 79.05  ? 5   VAL H CG2 1 
ATOM 1969 N N   . GLN C 2 6   ? 321.620 307.240 417.638 1.00 83.12  ? 6   GLN H N   1 
ATOM 1970 C CA  . GLN C 2 6   ? 322.621 308.282 417.797 1.00 83.12  ? 6   GLN H CA  1 
ATOM 1971 C C   . GLN C 2 6   ? 323.711 308.080 416.758 1.00 83.12  ? 6   GLN H C   1 
ATOM 1972 O O   . GLN C 2 6   ? 323.876 306.989 416.206 1.00 83.12  ? 6   GLN H O   1 
ATOM 1973 C CB  . GLN C 2 6   ? 323.206 308.292 419.214 1.00 83.12  ? 6   GLN H CB  1 
ATOM 1974 C CG  . GLN C 2 6   ? 323.971 307.037 419.582 1.00 83.12  ? 6   GLN H CG  1 
ATOM 1975 C CD  . GLN C 2 6   ? 323.095 305.995 420.244 1.00 83.12  ? 6   GLN H CD  1 
ATOM 1976 O OE1 . GLN C 2 6   ? 321.869 306.061 420.171 1.00 83.12  ? 6   GLN H OE1 1 
ATOM 1977 N NE2 . GLN C 2 6   ? 323.722 305.024 420.897 1.00 83.12  ? 6   GLN H NE2 1 
ATOM 1978 N N   . LEU C 2 7   ? 324.451 309.152 416.492 1.00 80.76  ? 7   LEU H N   1 
ATOM 1979 C CA  . LEU C 2 7   ? 325.443 309.183 415.422 1.00 80.76  ? 7   LEU H CA  1 
ATOM 1980 C C   . LEU C 2 7   ? 326.807 309.486 416.029 1.00 80.76  ? 7   LEU H C   1 
ATOM 1981 O O   . LEU C 2 7   ? 327.060 310.614 416.464 1.00 80.76  ? 7   LEU H O   1 
ATOM 1982 C CB  . LEU C 2 7   ? 325.063 310.225 414.373 1.00 80.76  ? 7   LEU H CB  1 
ATOM 1983 C CG  . LEU C 2 7   ? 323.779 309.927 413.596 1.00 80.76  ? 7   LEU H CG  1 
ATOM 1984 C CD1 . LEU C 2 7   ? 323.418 311.079 412.687 1.00 80.76  ? 7   LEU H CD1 1 
ATOM 1985 C CD2 . LEU C 2 7   ? 323.911 308.650 412.801 1.00 80.76  ? 7   LEU H CD2 1 
ATOM 1986 N N   . GLN C 2 8   ? 327.681 308.484 416.056 1.00 85.82  ? 8   GLN H N   1 
ATOM 1987 C CA  . GLN C 2 8   ? 329.027 308.682 416.576 1.00 85.82  ? 8   GLN H CA  1 
ATOM 1988 C C   . GLN C 2 8   ? 329.871 309.490 415.599 1.00 85.82  ? 8   GLN H C   1 
ATOM 1989 O O   . GLN C 2 8   ? 329.777 309.319 414.382 1.00 85.82  ? 8   GLN H O   1 
ATOM 1990 C CB  . GLN C 2 8   ? 329.703 307.338 416.847 1.00 85.82  ? 8   GLN H CB  1 
ATOM 1991 C CG  . GLN C 2 8   ? 328.792 306.256 417.398 1.00 85.82  ? 8   GLN H CG  1 
ATOM 1992 C CD  . GLN C 2 8   ? 328.099 306.667 418.680 1.00 85.82  ? 8   GLN H CD  1 
ATOM 1993 O OE1 . GLN C 2 8   ? 326.923 306.373 418.882 1.00 85.82  ? 8   GLN H OE1 1 
ATOM 1994 N NE2 . GLN C 2 8   ? 328.829 307.346 419.560 1.00 85.82  ? 8   GLN H NE2 1 
ATOM 1995 N N   . GLN C 2 9   ? 330.703 310.371 416.142 1.00 86.03  ? 9   GLN H N   1 
ATOM 1996 C CA  . GLN C 2 9   ? 331.674 311.106 415.352 1.00 86.03  ? 9   GLN H CA  1 
ATOM 1997 C C   . GLN C 2 9   ? 333.034 311.033 416.028 1.00 86.03  ? 9   GLN H C   1 
ATOM 1998 O O   . GLN C 2 9   ? 333.117 310.999 417.260 1.00 86.03  ? 9   GLN H O   1 
ATOM 1999 C CB  . GLN C 2 9   ? 331.252 312.570 415.174 1.00 86.03  ? 9   GLN H CB  1 
ATOM 2000 C CG  . GLN C 2 9   ? 330.092 312.750 414.212 1.00 86.03  ? 9   GLN H CG  1 
ATOM 2001 C CD  . GLN C 2 9   ? 330.104 314.096 413.521 1.00 86.03  ? 9   GLN H CD  1 
ATOM 2002 O OE1 . GLN C 2 9   ? 329.164 314.877 413.645 1.00 86.03  ? 9   GLN H OE1 1 
ATOM 2003 N NE2 . GLN C 2 9   ? 331.165 314.367 412.775 1.00 86.03  ? 9   GLN H NE2 1 
ATOM 2004 N N   . PRO C 2 10  ? 334.118 310.995 415.246 1.00 91.06  ? 10  PRO H N   1 
ATOM 2005 C CA  . PRO C 2 10  ? 335.444 310.775 415.852 1.00 91.06  ? 10  PRO H CA  1 
ATOM 2006 C C   . PRO C 2 10  ? 335.860 311.852 416.839 1.00 91.06  ? 10  PRO H C   1 
ATOM 2007 O O   . PRO C 2 10  ? 336.526 311.545 417.835 1.00 91.06  ? 10  PRO H O   1 
ATOM 2008 C CB  . PRO C 2 10  ? 336.376 310.727 414.633 1.00 91.06  ? 10  PRO H CB  1 
ATOM 2009 C CG  . PRO C 2 10  ? 335.648 311.474 413.568 1.00 91.06  ? 10  PRO H CG  1 
ATOM 2010 C CD  . PRO C 2 10  ? 334.200 311.168 413.787 1.00 91.06  ? 10  PRO H CD  1 
ATOM 2011 N N   . GLY C 2 11  ? 335.487 313.097 416.599 1.00 95.09  ? 11  GLY H N   1 
ATOM 2012 C CA  . GLY C 2 11  ? 335.907 314.203 417.435 1.00 95.09  ? 11  GLY H CA  1 
ATOM 2013 C C   . GLY C 2 11  ? 336.885 315.110 416.710 1.00 95.09  ? 11  GLY H C   1 
ATOM 2014 O O   . GLY C 2 11  ? 337.137 314.977 415.510 1.00 95.09  ? 11  GLY H O   1 
ATOM 2015 N N   . THR C 2 12  ? 337.449 316.043 417.474 1.00 98.26  ? 12  THR H N   1 
ATOM 2016 C CA  . THR C 2 12  ? 338.322 317.059 416.899 1.00 98.26  ? 12  THR H CA  1 
ATOM 2017 C C   . THR C 2 12  ? 339.549 316.431 416.247 1.00 98.26  ? 12  THR H C   1 
ATOM 2018 O O   . THR C 2 12  ? 340.083 315.426 416.722 1.00 98.26  ? 12  THR H O   1 
ATOM 2019 C CB  . THR C 2 12  ? 338.754 318.056 417.978 1.00 98.26  ? 12  THR H CB  1 
ATOM 2020 O OG1 . THR C 2 12  ? 339.660 319.013 417.413 1.00 98.26  ? 12  THR H OG1 1 
ATOM 2021 C CG2 . THR C 2 12  ? 339.431 317.340 419.140 1.00 98.26  ? 12  THR H CG2 1 
ATOM 2022 N N   . GLU C 2 13  ? 339.979 317.024 415.134 1.00 98.53  ? 13  GLU H N   1 
ATOM 2023 C CA  . GLU C 2 13  ? 341.177 316.595 414.428 1.00 98.53  ? 13  GLU H CA  1 
ATOM 2024 C C   . GLU C 2 13  ? 341.955 317.822 413.976 1.00 98.53  ? 13  GLU H C   1 
ATOM 2025 O O   . GLU C 2 13  ? 341.383 318.893 413.760 1.00 98.53  ? 13  GLU H O   1 
ATOM 2026 C CB  . GLU C 2 13  ? 340.844 315.711 413.219 1.00 98.53  ? 13  GLU H CB  1 
ATOM 2027 C CG  . GLU C 2 13  ? 340.069 314.450 413.563 1.00 98.53  ? 13  GLU H CG  1 
ATOM 2028 C CD  . GLU C 2 13  ? 340.466 313.269 412.703 1.00 98.53  ? 13  GLU H CD  1 
ATOM 2029 O OE1 . GLU C 2 13  ? 341.654 312.887 412.729 1.00 98.53  ? 13  GLU H OE1 1 
ATOM 2030 O OE2 . GLU C 2 13  ? 339.590 312.723 412.001 1.00 98.53  ? 13  GLU H OE2 1 
ATOM 2031 N N   . LEU C 2 14  ? 343.268 317.654 413.833 1.00 101.35 ? 14  LEU H N   1 
ATOM 2032 C CA  . LEU C 2 14  ? 344.166 318.730 413.433 1.00 101.35 ? 14  LEU H CA  1 
ATOM 2033 C C   . LEU C 2 14  ? 344.958 318.283 412.214 1.00 101.35 ? 14  LEU H C   1 
ATOM 2034 O O   . LEU C 2 14  ? 345.514 317.180 412.204 1.00 101.35 ? 14  LEU H O   1 
ATOM 2035 C CB  . LEU C 2 14  ? 345.104 319.111 414.585 1.00 101.35 ? 14  LEU H CB  1 
ATOM 2036 C CG  . LEU C 2 14  ? 346.018 320.332 414.462 1.00 101.35 ? 14  LEU H CG  1 
ATOM 2037 C CD1 . LEU C 2 14  ? 346.317 320.878 415.847 1.00 101.35 ? 14  LEU H CD1 1 
ATOM 2038 C CD2 . LEU C 2 14  ? 347.317 320.001 413.745 1.00 101.35 ? 14  LEU H CD2 1 
ATOM 2039 N N   . VAL C 2 15  ? 345.008 319.136 411.193 1.00 103.67 ? 15  VAL H N   1 
ATOM 2040 C CA  . VAL C 2 15  ? 345.682 318.830 409.937 1.00 103.67 ? 15  VAL H CA  1 
ATOM 2041 C C   . VAL C 2 15  ? 346.394 320.074 409.429 1.00 103.67 ? 15  VAL H C   1 
ATOM 2042 O O   . VAL C 2 15  ? 345.946 321.202 409.667 1.00 103.67 ? 15  VAL H O   1 
ATOM 2043 C CB  . VAL C 2 15  ? 344.705 318.297 408.867 1.00 103.67 ? 15  VAL H CB  1 
ATOM 2044 C CG1 . VAL C 2 15  ? 344.066 316.996 409.323 1.00 103.67 ? 15  VAL H CG1 1 
ATOM 2045 C CG2 . VAL C 2 15  ? 343.646 319.339 408.553 1.00 103.67 ? 15  VAL H CG2 1 
ATOM 2046 N N   . LYS C 2 16  ? 347.509 319.865 408.738 1.00 107.35 ? 16  LYS H N   1 
ATOM 2047 C CA  . LYS C 2 16  ? 348.272 320.946 408.139 1.00 107.35 ? 16  LYS H CA  1 
ATOM 2048 C C   . LYS C 2 16  ? 347.570 321.478 406.893 1.00 107.35 ? 16  LYS H C   1 
ATOM 2049 O O   . LYS C 2 16  ? 346.755 320.782 406.280 1.00 107.35 ? 16  LYS H O   1 
ATOM 2050 C CB  . LYS C 2 16  ? 349.675 320.461 407.789 1.00 107.35 ? 16  LYS H CB  1 
ATOM 2051 C CG  . LYS C 2 16  ? 350.603 320.324 408.987 1.00 107.35 ? 16  LYS H CG  1 
ATOM 2052 C CD  . LYS C 2 16  ? 350.377 321.438 410.002 1.00 107.35 ? 16  LYS H CD  1 
ATOM 2053 C CE  . LYS C 2 16  ? 351.144 321.179 411.289 1.00 107.35 ? 16  LYS H CE  1 
ATOM 2054 N NZ  . LYS C 2 16  ? 351.484 322.440 412.003 1.00 107.35 ? 16  LYS H NZ  1 
ATOM 2055 N N   . PRO C 2 17  ? 347.863 322.718 406.500 1.00 108.93 ? 17  PRO H N   1 
ATOM 2056 C CA  . PRO C 2 17  ? 347.215 323.288 405.315 1.00 108.93 ? 17  PRO H CA  1 
ATOM 2057 C C   . PRO C 2 17  ? 347.569 322.521 404.050 1.00 108.93 ? 17  PRO H C   1 
ATOM 2058 O O   . PRO C 2 17  ? 348.605 321.860 403.964 1.00 108.93 ? 17  PRO H O   1 
ATOM 2059 C CB  . PRO C 2 17  ? 347.758 324.720 405.267 1.00 108.93 ? 17  PRO H CB  1 
ATOM 2060 C CG  . PRO C 2 17  ? 348.147 325.017 406.670 1.00 108.93 ? 17  PRO H CG  1 
ATOM 2061 C CD  . PRO C 2 17  ? 348.662 323.723 407.221 1.00 108.93 ? 17  PRO H CD  1 
ATOM 2062 N N   . GLY C 2 18  ? 346.683 322.614 403.064 1.00 108.55 ? 18  GLY H N   1 
ATOM 2063 C CA  . GLY C 2 18  ? 346.883 321.944 401.790 1.00 108.55 ? 18  GLY H CA  1 
ATOM 2064 C C   . GLY C 2 18  ? 346.841 320.433 401.856 1.00 108.55 ? 18  GLY H C   1 
ATOM 2065 O O   . GLY C 2 18  ? 347.684 319.767 401.243 1.00 108.55 ? 18  GLY H O   1 
ATOM 2066 N N   . ALA C 2 19  ? 345.877 319.872 402.583 1.00 105.30 ? 19  ALA H N   1 
ATOM 2067 C CA  . ALA C 2 19  ? 345.745 318.430 402.730 1.00 105.30 ? 19  ALA H CA  1 
ATOM 2068 C C   . ALA C 2 19  ? 344.272 318.055 402.623 1.00 105.30 ? 19  ALA H C   1 
ATOM 2069 O O   . ALA C 2 19  ? 343.412 318.900 402.356 1.00 105.30 ? 19  ALA H O   1 
ATOM 2070 C CB  . ALA C 2 19  ? 346.349 317.952 404.056 1.00 105.30 ? 19  ALA H CB  1 
ATOM 2071 N N   . SER C 2 20  ? 343.982 316.774 402.834 1.00 98.32  ? 20  SER H N   1 
ATOM 2072 C CA  . SER C 2 20  ? 342.630 316.245 402.749 1.00 98.32  ? 20  SER H CA  1 
ATOM 2073 C C   . SER C 2 20  ? 342.284 315.493 404.027 1.00 98.32  ? 20  SER H C   1 
ATOM 2074 O O   . SER C 2 20  ? 343.148 314.873 404.653 1.00 98.32  ? 20  SER H O   1 
ATOM 2075 C CB  . SER C 2 20  ? 342.474 315.319 401.540 1.00 98.32  ? 20  SER H CB  1 
ATOM 2076 O OG  . SER C 2 20  ? 343.062 314.056 401.790 1.00 98.32  ? 20  SER H OG  1 
ATOM 2077 N N   . VAL C 2 21  ? 341.008 315.552 404.414 1.00 92.32  ? 21  VAL H N   1 
ATOM 2078 C CA  . VAL C 2 21  ? 340.555 314.988 405.679 1.00 92.32  ? 21  VAL H CA  1 
ATOM 2079 C C   . VAL C 2 21  ? 339.326 314.128 405.409 1.00 92.32  ? 21  VAL H C   1 
ATOM 2080 O O   . VAL C 2 21  ? 338.551 314.396 404.487 1.00 92.32  ? 21  VAL H O   1 
ATOM 2081 C CB  . VAL C 2 21  ? 340.249 316.104 406.704 1.00 92.32  ? 21  VAL H CB  1 
ATOM 2082 C CG1 . VAL C 2 21  ? 339.691 315.535 408.000 1.00 92.32  ? 21  VAL H CG1 1 
ATOM 2083 C CG2 . VAL C 2 21  ? 341.479 316.937 406.956 1.00 92.32  ? 21  VAL H CG2 1 
ATOM 2084 N N   . LYS C 2 22  ? 339.146 313.087 406.226 1.00 85.50  ? 22  LYS H N   1 
ATOM 2085 C CA  . LYS C 2 22  ? 338.128 312.074 405.967 1.00 85.50  ? 22  LYS H CA  1 
ATOM 2086 C C   . LYS C 2 22  ? 336.747 312.429 406.516 1.00 85.50  ? 22  LYS H C   1 
ATOM 2087 O O   . LYS C 2 22  ? 335.743 312.168 405.846 1.00 85.50  ? 22  LYS H O   1 
ATOM 2088 C CB  . LYS C 2 22  ? 338.577 310.727 406.539 1.00 85.50  ? 22  LYS H CB  1 
ATOM 2089 C CG  . LYS C 2 22  ? 337.676 309.560 406.158 1.00 85.50  ? 22  LYS H CG  1 
ATOM 2090 C CD  . LYS C 2 22  ? 337.296 309.598 404.685 1.00 85.50  ? 22  LYS H CD  1 
ATOM 2091 C CE  . LYS C 2 22  ? 338.464 309.224 403.796 1.00 85.50  ? 22  LYS H CE  1 
ATOM 2092 N NZ  . LYS C 2 22  ? 338.072 309.199 402.361 1.00 85.50  ? 22  LYS H NZ  1 
ATOM 2093 N N   . LEU C 2 23  ? 336.664 312.996 407.719 1.00 83.17  ? 23  LEU H N   1 
ATOM 2094 C CA  . LEU C 2 23  ? 335.384 313.297 408.365 1.00 83.17  ? 23  LEU H CA  1 
ATOM 2095 C C   . LEU C 2 23  ? 334.498 312.052 408.440 1.00 83.17  ? 23  LEU H C   1 
ATOM 2096 O O   . LEU C 2 23  ? 333.453 311.958 407.796 1.00 83.17  ? 23  LEU H O   1 
ATOM 2097 C CB  . LEU C 2 23  ? 334.642 314.437 407.658 1.00 83.17  ? 23  LEU H CB  1 
ATOM 2098 C CG  . LEU C 2 23  ? 334.927 315.908 407.978 1.00 83.17  ? 23  LEU H CG  1 
ATOM 2099 C CD1 . LEU C 2 23  ? 334.619 316.218 409.434 1.00 83.17  ? 23  LEU H CD1 1 
ATOM 2100 C CD2 . LEU C 2 23  ? 336.334 316.312 407.620 1.00 83.17  ? 23  LEU H CD2 1 
ATOM 2101 N N   . SER C 2 24  ? 334.941 311.082 409.231 1.00 83.62  ? 24  SER H N   1 
ATOM 2102 C CA  . SER C 2 24  ? 334.218 309.827 409.352 1.00 83.62  ? 24  SER H CA  1 
ATOM 2103 C C   . SER C 2 24  ? 332.920 310.016 410.134 1.00 83.62  ? 24  SER H C   1 
ATOM 2104 O O   . SER C 2 24  ? 332.707 311.024 410.814 1.00 83.62  ? 24  SER H O   1 
ATOM 2105 C CB  . SER C 2 24  ? 335.092 308.771 410.026 1.00 83.62  ? 24  SER H CB  1 
ATOM 2106 O OG  . SER C 2 24  ? 334.378 307.562 410.212 1.00 83.62  ? 24  SER H OG  1 
ATOM 2107 N N   . CYS C 2 25  ? 332.041 309.022 410.025 1.00 83.79  ? 25  CYS H N   1 
ATOM 2108 C CA  . CYS C 2 25  ? 330.766 309.021 410.727 1.00 83.79  ? 25  CYS H CA  1 
ATOM 2109 C C   . CYS C 2 25  ? 330.316 307.587 410.954 1.00 83.79  ? 25  CYS H C   1 
ATOM 2110 O O   . CYS C 2 25  ? 330.761 306.662 410.273 1.00 83.79  ? 25  CYS H O   1 
ATOM 2111 C CB  . CYS C 2 25  ? 329.689 309.786 409.956 1.00 83.79  ? 25  CYS H CB  1 
ATOM 2112 S SG  . CYS C 2 25  ? 328.113 309.858 410.825 1.00 83.79  ? 25  CYS H SG  1 
ATOM 2113 N N   . LYS C 2 26  ? 329.423 307.408 411.923 1.00 83.61  ? 26  LYS H N   1 
ATOM 2114 C CA  . LYS C 2 26  ? 328.887 306.095 412.248 1.00 83.61  ? 26  LYS H CA  1 
ATOM 2115 C C   . LYS C 2 26  ? 327.421 306.225 412.626 1.00 83.61  ? 26  LYS H C   1 
ATOM 2116 O O   . LYS C 2 26  ? 327.046 307.126 413.381 1.00 83.61  ? 26  LYS H O   1 
ATOM 2117 C CB  . LYS C 2 26  ? 329.672 305.443 413.391 1.00 83.61  ? 26  LYS H CB  1 
ATOM 2118 C CG  . LYS C 2 26  ? 329.120 304.104 413.840 1.00 83.61  ? 26  LYS H CG  1 
ATOM 2119 C CD  . LYS C 2 26  ? 329.961 302.961 413.302 1.00 83.61  ? 26  LYS H CD  1 
ATOM 2120 C CE  . LYS C 2 26  ? 329.417 301.618 413.755 1.00 83.61  ? 26  LYS H CE  1 
ATOM 2121 N NZ  . LYS C 2 26  ? 327.966 301.478 413.459 1.00 83.61  ? 26  LYS H NZ  1 
ATOM 2122 N N   . ALA C 2 27  ? 326.596 305.320 412.106 1.00 82.40  ? 27  ALA H N   1 
ATOM 2123 C CA  . ALA C 2 27  ? 325.159 305.334 412.339 1.00 82.40  ? 27  ALA H CA  1 
ATOM 2124 C C   . ALA C 2 27  ? 324.754 304.088 413.110 1.00 82.40  ? 27  ALA H C   1 
ATOM 2125 O O   . ALA C 2 27  ? 325.136 302.974 412.741 1.00 82.40  ? 27  ALA H O   1 
ATOM 2126 C CB  . ALA C 2 27  ? 324.389 305.416 411.021 1.00 82.40  ? 27  ALA H CB  1 
ATOM 2127 N N   . SER C 2 28  ? 323.973 304.276 414.171 1.00 82.27  ? 28  SER H N   1 
ATOM 2128 C CA  . SER C 2 28  ? 323.553 303.174 415.020 1.00 82.27  ? 28  SER H CA  1 
ATOM 2129 C C   . SER C 2 28  ? 322.089 303.340 415.395 1.00 82.27  ? 28  SER H C   1 
ATOM 2130 O O   . SER C 2 28  ? 321.569 304.456 415.456 1.00 82.27  ? 28  SER H O   1 
ATOM 2131 C CB  . SER C 2 28  ? 324.406 303.090 416.292 1.00 82.27  ? 28  SER H CB  1 
ATOM 2132 O OG  . SER C 2 28  ? 325.770 302.882 415.976 1.00 82.27  ? 28  SER H OG  1 
ATOM 2133 N N   . GLY C 2 29  ? 321.430 302.210 415.649 1.00 80.31  ? 29  GLY H N   1 
ATOM 2134 C CA  . GLY C 2 29  ? 320.070 302.200 416.140 1.00 80.31  ? 29  GLY H CA  1 
ATOM 2135 C C   . GLY C 2 29  ? 318.994 302.214 415.078 1.00 80.31  ? 29  GLY H C   1 
ATOM 2136 O O   . GLY C 2 29  ? 317.812 302.079 415.419 1.00 80.31  ? 29  GLY H O   1 
ATOM 2137 N N   . TYR C 2 30  ? 319.354 302.368 413.808 1.00 77.37  ? 30  TYR H N   1 
ATOM 2138 C CA  . TYR C 2 30  ? 318.365 302.426 412.742 1.00 77.37  ? 30  TYR H CA  1 
ATOM 2139 C C   . TYR C 2 30  ? 318.984 301.877 411.469 1.00 77.37  ? 30  TYR H C   1 
ATOM 2140 O O   . TYR C 2 30  ? 320.208 301.793 411.337 1.00 77.37  ? 30  TYR H O   1 
ATOM 2141 C CB  . TYR C 2 30  ? 317.863 303.855 412.514 1.00 77.37  ? 30  TYR H CB  1 
ATOM 2142 C CG  . TYR C 2 30  ? 318.887 304.772 411.883 1.00 77.37  ? 30  TYR H CG  1 
ATOM 2143 C CD1 . TYR C 2 30  ? 319.850 305.406 412.655 1.00 77.37  ? 30  TYR H CD1 1 
ATOM 2144 C CD2 . TYR C 2 30  ? 318.886 305.008 410.517 1.00 77.37  ? 30  TYR H CD2 1 
ATOM 2145 C CE1 . TYR C 2 30  ? 320.785 306.242 412.081 1.00 77.37  ? 30  TYR H CE1 1 
ATOM 2146 C CE2 . TYR C 2 30  ? 319.815 305.842 409.936 1.00 77.37  ? 30  TYR H CE2 1 
ATOM 2147 C CZ  . TYR C 2 30  ? 320.762 306.456 410.721 1.00 77.37  ? 30  TYR H CZ  1 
ATOM 2148 O OH  . TYR C 2 30  ? 321.687 307.290 410.139 1.00 77.37  ? 30  TYR H OH  1 
ATOM 2149 N N   . THR C 2 31  ? 318.124 301.504 410.528 1.00 76.21  ? 31  THR H N   1 
ATOM 2150 C CA  . THR C 2 31  ? 318.607 301.017 409.244 1.00 76.21  ? 31  THR H CA  1 
ATOM 2151 C C   . THR C 2 31  ? 319.240 302.159 408.455 1.00 76.21  ? 31  THR H C   1 
ATOM 2152 O O   . THR C 2 31  ? 318.570 303.120 408.066 1.00 76.21  ? 31  THR H O   1 
ATOM 2153 C CB  . THR C 2 31  ? 317.471 300.352 408.460 1.00 76.21  ? 31  THR H CB  1 
ATOM 2154 O OG1 . THR C 2 31  ? 317.948 299.937 407.173 1.00 76.21  ? 31  THR H OG1 1 
ATOM 2155 C CG2 . THR C 2 31  ? 316.258 301.268 408.313 1.00 76.21  ? 31  THR H CG2 1 
ATOM 2156 N N   . PHE C 2 32  ? 320.553 302.057 408.241 1.00 75.49  ? 32  PHE H N   1 
ATOM 2157 C CA  . PHE C 2 32  ? 321.282 303.094 407.517 1.00 75.49  ? 32  PHE H CA  1 
ATOM 2158 C C   . PHE C 2 32  ? 320.793 303.207 406.082 1.00 75.49  ? 32  PHE H C   1 
ATOM 2159 O O   . PHE C 2 32  ? 320.984 304.238 405.429 1.00 75.49  ? 32  PHE H O   1 
ATOM 2160 C CB  . PHE C 2 32  ? 322.775 302.777 407.554 1.00 75.49  ? 32  PHE H CB  1 
ATOM 2161 C CG  . PHE C 2 32  ? 323.648 303.871 407.030 1.00 75.49  ? 32  PHE H CG  1 
ATOM 2162 C CD1 . PHE C 2 32  ? 323.574 305.144 407.559 1.00 75.49  ? 32  PHE H CD1 1 
ATOM 2163 C CD2 . PHE C 2 32  ? 324.557 303.622 406.020 1.00 75.49  ? 32  PHE H CD2 1 
ATOM 2164 C CE1 . PHE C 2 32  ? 324.383 306.150 407.086 1.00 75.49  ? 32  PHE H CE1 1 
ATOM 2165 C CE2 . PHE C 2 32  ? 325.367 304.626 405.541 1.00 75.49  ? 32  PHE H CE2 1 
ATOM 2166 C CZ  . PHE C 2 32  ? 325.279 305.891 406.075 1.00 75.49  ? 32  PHE H CZ  1 
ATOM 2167 N N   . THR C 2 33  ? 320.142 302.157 405.588 1.00 74.95  ? 33  THR H N   1 
ATOM 2168 C CA  . THR C 2 33  ? 319.745 302.054 404.192 1.00 74.95  ? 33  THR H CA  1 
ATOM 2169 C C   . THR C 2 33  ? 318.722 303.108 403.779 1.00 74.95  ? 33  THR H C   1 
ATOM 2170 O O   . THR C 2 33  ? 318.777 303.593 402.644 1.00 74.95  ? 33  THR H O   1 
ATOM 2171 C CB  . THR C 2 33  ? 319.196 300.643 403.953 1.00 74.95  ? 33  THR H CB  1 
ATOM 2172 O OG1 . THR C 2 33  ? 320.218 299.682 404.246 1.00 74.95  ? 33  THR H OG1 1 
ATOM 2173 C CG2 . THR C 2 33  ? 318.735 300.453 402.532 1.00 74.95  ? 33  THR H CG2 1 
ATOM 2174 N N   . ASN C 2 34  ? 317.804 303.486 404.669 1.00 70.25  ? 34  ASN H N   1 
ATOM 2175 C CA  . ASN C 2 34  ? 316.606 304.201 404.242 1.00 70.25  ? 34  ASN H CA  1 
ATOM 2176 C C   . ASN C 2 34  ? 316.755 305.720 404.248 1.00 70.25  ? 34  ASN H C   1 
ATOM 2177 O O   . ASN C 2 34  ? 316.120 306.394 403.431 1.00 70.25  ? 34  ASN H O   1 
ATOM 2178 C CB  . ASN C 2 34  ? 315.427 303.800 405.127 1.00 70.25  ? 34  ASN H CB  1 
ATOM 2179 C CG  . ASN C 2 34  ? 314.917 302.410 404.819 1.00 70.25  ? 34  ASN H CG  1 
ATOM 2180 O OD1 . ASN C 2 34  ? 315.573 301.636 404.124 1.00 70.25  ? 34  ASN H OD1 1 
ATOM 2181 N ND2 . ASN C 2 34  ? 313.738 302.084 405.334 1.00 70.25  ? 34  ASN H ND2 1 
ATOM 2182 N N   . TYR C 2 35  ? 317.562 306.283 405.142 1.00 66.33  ? 35  TYR H N   1 
ATOM 2183 C CA  . TYR C 2 35  ? 317.522 307.711 405.430 1.00 66.33  ? 35  TYR H CA  1 
ATOM 2184 C C   . TYR C 2 35  ? 318.689 308.451 404.790 1.00 66.33  ? 35  TYR H C   1 
ATOM 2185 O O   . TYR C 2 35  ? 319.791 307.910 404.672 1.00 66.33  ? 35  TYR H O   1 
ATOM 2186 C CB  . TYR C 2 35  ? 317.531 307.960 406.939 1.00 66.33  ? 35  TYR H CB  1 
ATOM 2187 C CG  . TYR C 2 35  ? 316.350 307.361 407.661 1.00 66.33  ? 35  TYR H CG  1 
ATOM 2188 C CD1 . TYR C 2 35  ? 316.319 306.014 407.989 1.00 66.33  ? 35  TYR H CD1 1 
ATOM 2189 C CD2 . TYR C 2 35  ? 315.262 308.144 408.010 1.00 66.33  ? 35  TYR H CD2 1 
ATOM 2190 C CE1 . TYR C 2 35  ? 315.241 305.467 408.646 1.00 66.33  ? 35  TYR H CE1 1 
ATOM 2191 C CE2 . TYR C 2 35  ? 314.179 307.605 408.667 1.00 66.33  ? 35  TYR H CE2 1 
ATOM 2192 C CZ  . TYR C 2 35  ? 314.174 306.267 408.982 1.00 66.33  ? 35  TYR H CZ  1 
ATOM 2193 O OH  . TYR C 2 35  ? 313.094 305.727 409.638 1.00 66.33  ? 35  TYR H OH  1 
ATOM 2194 N N   . TRP C 2 36  ? 318.436 309.694 404.384 1.00 58.08  ? 36  TRP H N   1 
ATOM 2195 C CA  . TRP C 2 36  ? 319.483 310.570 403.881 1.00 58.08  ? 36  TRP H CA  1 
ATOM 2196 C C   . TRP C 2 36  ? 320.400 311.012 405.016 1.00 58.08  ? 36  TRP H C   1 
ATOM 2197 O O   . TRP C 2 36  ? 320.056 310.930 406.197 1.00 58.08  ? 36  TRP H O   1 
ATOM 2198 C CB  . TRP C 2 36  ? 318.887 311.811 403.217 1.00 58.08  ? 36  TRP H CB  1 
ATOM 2199 C CG  . TRP C 2 36  ? 318.080 311.556 401.991 1.00 58.08  ? 36  TRP H CG  1 
ATOM 2200 C CD1 . TRP C 2 36  ? 316.816 311.062 401.936 1.00 58.08  ? 36  TRP H CD1 1 
ATOM 2201 C CD2 . TRP C 2 36  ? 318.468 311.816 400.638 1.00 58.08  ? 36  TRP H CD2 1 
ATOM 2202 N NE1 . TRP C 2 36  ? 316.394 310.981 400.633 1.00 58.08  ? 36  TRP H NE1 1 
ATOM 2203 C CE2 . TRP C 2 36  ? 317.392 311.440 399.816 1.00 58.08  ? 36  TRP H CE2 1 
ATOM 2204 C CE3 . TRP C 2 36  ? 319.625 312.324 400.042 1.00 58.08  ? 36  TRP H CE3 1 
ATOM 2205 C CZ2 . TRP C 2 36  ? 317.438 311.552 398.432 1.00 58.08  ? 36  TRP H CZ2 1 
ATOM 2206 C CZ3 . TRP C 2 36  ? 319.666 312.436 398.667 1.00 58.08  ? 36  TRP H CZ3 1 
ATOM 2207 C CH2 . TRP C 2 36  ? 318.583 312.051 397.878 1.00 58.08  ? 36  TRP H CH2 1 
ATOM 2208 N N   . MET C 2 37  ? 321.581 311.496 404.642 1.00 63.37  ? 37  MET H N   1 
ATOM 2209 C CA  . MET C 2 37  ? 322.547 312.027 405.596 1.00 63.37  ? 37  MET H CA  1 
ATOM 2210 C C   . MET C 2 37  ? 323.002 313.399 405.128 1.00 63.37  ? 37  MET H C   1 
ATOM 2211 O O   . MET C 2 37  ? 323.513 313.537 404.013 1.00 63.37  ? 37  MET H O   1 
ATOM 2212 C CB  . MET C 2 37  ? 323.745 311.090 405.747 1.00 63.37  ? 37  MET H CB  1 
ATOM 2213 C CG  . MET C 2 37  ? 323.459 309.862 406.582 1.00 63.37  ? 37  MET H CG  1 
ATOM 2214 S SD  . MET C 2 37  ? 323.763 310.146 408.332 1.00 63.37  ? 37  MET H SD  1 
ATOM 2215 C CE  . MET C 2 37  ? 325.542 310.312 408.330 1.00 63.37  ? 37  MET H CE  1 
ATOM 2216 N N   . HIS C 2 38  ? 322.831 314.403 405.979 1.00 63.10  ? 38  HIS H N   1 
ATOM 2217 C CA  . HIS C 2 38  ? 323.225 315.769 405.674 1.00 63.10  ? 38  HIS H CA  1 
ATOM 2218 C C   . HIS C 2 38  ? 324.544 316.104 406.357 1.00 63.10  ? 38  HIS H C   1 
ATOM 2219 O O   . HIS C 2 38  ? 324.914 315.509 407.368 1.00 63.10  ? 38  HIS H O   1 
ATOM 2220 C CB  . HIS C 2 38  ? 322.151 316.763 406.120 1.00 63.10  ? 38  HIS H CB  1 
ATOM 2221 C CG  . HIS C 2 38  ? 320.823 316.564 405.461 1.00 63.10  ? 38  HIS H CG  1 
ATOM 2222 N ND1 . HIS C 2 38  ? 320.136 317.590 404.852 1.00 63.10  ? 38  HIS H ND1 1 
ATOM 2223 C CD2 . HIS C 2 38  ? 320.049 315.462 405.328 1.00 63.10  ? 38  HIS H CD2 1 
ATOM 2224 C CE1 . HIS C 2 38  ? 319.000 317.128 404.364 1.00 63.10  ? 38  HIS H CE1 1 
ATOM 2225 N NE2 . HIS C 2 38  ? 318.922 315.839 404.640 1.00 63.10  ? 38  HIS H NE2 1 
ATOM 2226 N N   . TRP C 2 39  ? 325.254 317.072 405.785 1.00 67.78  ? 39  TRP H N   1 
ATOM 2227 C CA  . TRP C 2 39  ? 326.490 317.582 406.362 1.00 67.78  ? 39  TRP H CA  1 
ATOM 2228 C C   . TRP C 2 39  ? 326.380 319.091 406.490 1.00 67.78  ? 39  TRP H C   1 
ATOM 2229 O O   . TRP C 2 39  ? 326.035 319.774 405.522 1.00 67.78  ? 39  TRP H O   1 
ATOM 2230 C CB  . TRP C 2 39  ? 327.703 317.197 405.510 1.00 67.78  ? 39  TRP H CB  1 
ATOM 2231 C CG  . TRP C 2 39  ? 328.065 315.754 405.634 1.00 67.78  ? 39  TRP H CG  1 
ATOM 2232 C CD1 . TRP C 2 39  ? 327.608 314.730 404.865 1.00 67.78  ? 39  TRP H CD1 1 
ATOM 2233 C CD2 . TRP C 2 39  ? 328.953 315.170 406.593 1.00 67.78  ? 39  TRP H CD2 1 
ATOM 2234 N NE1 . TRP C 2 39  ? 328.155 313.544 405.280 1.00 67.78  ? 39  TRP H NE1 1 
ATOM 2235 C CE2 . TRP C 2 39  ? 328.986 313.787 406.341 1.00 67.78  ? 39  TRP H CE2 1 
ATOM 2236 C CE3 . TRP C 2 39  ? 329.723 315.682 407.639 1.00 67.78  ? 39  TRP H CE3 1 
ATOM 2237 C CZ2 . TRP C 2 39  ? 329.758 312.910 407.094 1.00 67.78  ? 39  TRP H CZ2 1 
ATOM 2238 C CZ3 . TRP C 2 39  ? 330.489 314.810 408.384 1.00 67.78  ? 39  TRP H CZ3 1 
ATOM 2239 C CH2 . TRP C 2 39  ? 330.500 313.440 408.109 1.00 67.78  ? 39  TRP H CH2 1 
ATOM 2240 N N   . VAL C 2 40  ? 326.665 319.606 407.682 1.00 71.13  ? 40  VAL H N   1 
ATOM 2241 C CA  . VAL C 2 40  ? 326.472 321.013 408.004 1.00 71.13  ? 40  VAL H CA  1 
ATOM 2242 C C   . VAL C 2 40  ? 327.755 321.553 408.620 1.00 71.13  ? 40  VAL H C   1 
ATOM 2243 O O   . VAL C 2 40  ? 328.325 320.927 409.519 1.00 71.13  ? 40  VAL H O   1 
ATOM 2244 C CB  . VAL C 2 40  ? 325.282 321.208 408.963 1.00 71.13  ? 40  VAL H CB  1 
ATOM 2245 C CG1 . VAL C 2 40  ? 325.303 322.594 409.578 1.00 71.13  ? 40  VAL H CG1 1 
ATOM 2246 C CG2 . VAL C 2 40  ? 323.975 320.962 408.236 1.00 71.13  ? 40  VAL H CG2 1 
ATOM 2247 N N   . LYS C 2 41  ? 328.206 322.708 408.138 1.00 76.76  ? 41  LYS H N   1 
ATOM 2248 C CA  . LYS C 2 41  ? 329.398 323.370 408.651 1.00 76.76  ? 41  LYS H CA  1 
ATOM 2249 C C   . LYS C 2 41  ? 328.999 324.598 409.456 1.00 76.76  ? 41  LYS H C   1 
ATOM 2250 O O   . LYS C 2 41  ? 328.196 325.413 408.992 1.00 76.76  ? 41  LYS H O   1 
ATOM 2251 C CB  . LYS C 2 41  ? 330.337 323.779 407.517 1.00 76.76  ? 41  LYS H CB  1 
ATOM 2252 C CG  . LYS C 2 41  ? 331.564 324.532 407.999 1.00 76.76  ? 41  LYS H CG  1 
ATOM 2253 C CD  . LYS C 2 41  ? 332.478 324.935 406.856 1.00 76.76  ? 41  LYS H CD  1 
ATOM 2254 C CE  . LYS C 2 41  ? 332.067 326.264 406.253 1.00 76.76  ? 41  LYS H CE  1 
ATOM 2255 N NZ  . LYS C 2 41  ? 333.099 326.770 405.308 1.00 76.76  ? 41  LYS H NZ  1 
ATOM 2256 N N   . GLN C 2 42  ? 329.564 324.733 410.654 1.00 81.52  ? 42  GLN H N   1 
ATOM 2257 C CA  . GLN C 2 42  ? 329.305 325.874 411.527 1.00 81.52  ? 42  GLN H CA  1 
ATOM 2258 C C   . GLN C 2 42  ? 330.623 326.547 411.877 1.00 81.52  ? 42  GLN H C   1 
ATOM 2259 O O   . GLN C 2 42  ? 331.372 326.053 412.725 1.00 81.52  ? 42  GLN H O   1 
ATOM 2260 C CB  . GLN C 2 42  ? 328.574 325.447 412.795 1.00 81.52  ? 42  GLN H CB  1 
ATOM 2261 C CG  . GLN C 2 42  ? 327.924 326.604 413.527 1.00 81.52  ? 42  GLN H CG  1 
ATOM 2262 C CD  . GLN C 2 42  ? 327.750 326.334 415.002 1.00 81.52  ? 42  GLN H CD  1 
ATOM 2263 O OE1 . GLN C 2 42  ? 327.775 325.186 415.442 1.00 81.52  ? 42  GLN H OE1 1 
ATOM 2264 N NE2 . GLN C 2 42  ? 327.566 327.394 415.777 1.00 81.52  ? 42  GLN H NE2 1 
ATOM 2265 N N   . ARG C 2 43  ? 330.900 327.669 411.235 1.00 91.95  ? 43  ARG H N   1 
ATOM 2266 C CA  . ARG C 2 43  ? 332.049 328.479 411.614 1.00 91.95  ? 43  ARG H CA  1 
ATOM 2267 C C   . ARG C 2 43  ? 331.759 329.172 412.940 1.00 91.95  ? 43  ARG H C   1 
ATOM 2268 O O   . ARG C 2 43  ? 330.660 329.704 413.121 1.00 91.95  ? 43  ARG H O   1 
ATOM 2269 C CB  . ARG C 2 43  ? 332.355 329.506 410.532 1.00 91.95  ? 43  ARG H CB  1 
ATOM 2270 C CG  . ARG C 2 43  ? 333.792 329.984 410.507 1.00 91.95  ? 43  ARG H CG  1 
ATOM 2271 C CD  . ARG C 2 43  ? 334.008 330.975 409.383 1.00 91.95  ? 43  ARG H CD  1 
ATOM 2272 N NE  . ARG C 2 43  ? 333.653 330.406 408.090 1.00 91.95  ? 43  ARG H NE  1 
ATOM 2273 C CZ  . ARG C 2 43  ? 333.548 331.105 406.969 1.00 91.95  ? 43  ARG H CZ  1 
ATOM 2274 N NH1 . ARG C 2 43  ? 333.768 332.409 406.943 1.00 91.95  ? 43  ARG H NH1 1 
ATOM 2275 N NH2 . ARG C 2 43  ? 333.215 330.480 405.843 1.00 91.95  ? 43  ARG H NH2 1 
ATOM 2276 N N   . PRO C 2 44  ? 332.701 329.179 413.884 1.00 93.39  ? 44  PRO H N   1 
ATOM 2277 C CA  . PRO C 2 44  ? 332.416 329.737 415.217 1.00 93.39  ? 44  PRO H CA  1 
ATOM 2278 C C   . PRO C 2 44  ? 331.977 331.191 415.142 1.00 93.39  ? 44  PRO H C   1 
ATOM 2279 O O   . PRO C 2 44  ? 332.742 332.073 414.744 1.00 93.39  ? 44  PRO H O   1 
ATOM 2280 C CB  . PRO C 2 44  ? 333.750 329.582 415.958 1.00 93.39  ? 44  PRO H CB  1 
ATOM 2281 C CG  . PRO C 2 44  ? 334.777 329.402 414.882 1.00 93.39  ? 44  PRO H CG  1 
ATOM 2282 C CD  . PRO C 2 44  ? 334.077 328.669 413.785 1.00 93.39  ? 44  PRO H CD  1 
ATOM 2283 N N   . GLY C 2 45  ? 330.728 331.434 415.534 1.00 93.74  ? 45  GLY H N   1 
ATOM 2284 C CA  . GLY C 2 45  ? 330.157 332.763 415.509 1.00 93.74  ? 45  GLY H CA  1 
ATOM 2285 C C   . GLY C 2 45  ? 329.570 333.196 414.186 1.00 93.74  ? 45  GLY H C   1 
ATOM 2286 O O   . GLY C 2 45  ? 329.144 334.350 414.066 1.00 93.74  ? 45  GLY H O   1 
ATOM 2287 N N   . GLN C 2 46  ? 329.523 332.314 413.188 1.00 92.81  ? 46  GLN H N   1 
ATOM 2288 C CA  . GLN C 2 46  ? 329.053 332.680 411.859 1.00 92.81  ? 46  GLN H CA  1 
ATOM 2289 C C   . GLN C 2 46  ? 327.795 331.942 411.417 1.00 92.81  ? 46  GLN H C   1 
ATOM 2290 O O   . GLN C 2 46  ? 327.365 332.123 410.272 1.00 92.81  ? 46  GLN H O   1 
ATOM 2291 C CB  . GLN C 2 46  ? 330.163 332.454 410.822 1.00 92.81  ? 46  GLN H CB  1 
ATOM 2292 C CG  . GLN C 2 46  ? 331.556 333.011 411.169 1.00 92.81  ? 46  GLN H CG  1 
ATOM 2293 C CD  . GLN C 2 46  ? 331.565 334.374 411.864 1.00 92.81  ? 46  GLN H CD  1 
ATOM 2294 O OE1 . GLN C 2 46  ? 330.615 335.154 411.778 1.00 92.81  ? 46  GLN H OE1 1 
ATOM 2295 N NE2 . GLN C 2 46  ? 332.659 334.660 412.560 1.00 92.81  ? 46  GLN H NE2 1 
ATOM 2296 N N   . GLY C 2 47  ? 327.195 331.122 412.272 1.00 83.37  ? 47  GLY H N   1 
ATOM 2297 C CA  . GLY C 2 47  ? 325.959 330.452 411.922 1.00 83.37  ? 47  GLY H CA  1 
ATOM 2298 C C   . GLY C 2 47  ? 326.173 329.174 411.137 1.00 83.37  ? 47  GLY H C   1 
ATOM 2299 O O   . GLY C 2 47  ? 327.290 328.773 410.802 1.00 83.37  ? 47  GLY H O   1 
ATOM 2300 N N   . LEU C 2 48  ? 325.055 328.522 410.835 1.00 72.45  ? 48  LEU H N   1 
ATOM 2301 C CA  . LEU C 2 48  ? 325.061 327.228 410.171 1.00 72.45  ? 48  LEU H CA  1 
ATOM 2302 C C   . LEU C 2 48  ? 325.058 327.388 408.656 1.00 72.45  ? 48  LEU H C   1 
ATOM 2303 O O   . LEU C 2 48  ? 324.551 328.373 408.114 1.00 72.45  ? 48  LEU H O   1 
ATOM 2304 C CB  . LEU C 2 48  ? 323.853 326.401 410.611 1.00 72.45  ? 48  LEU H CB  1 
ATOM 2305 C CG  . LEU C 2 48  ? 323.828 325.977 412.079 1.00 72.45  ? 48  LEU H CG  1 
ATOM 2306 C CD1 . LEU C 2 48  ? 322.526 325.293 412.422 1.00 72.45  ? 48  LEU H CD1 1 
ATOM 2307 C CD2 . LEU C 2 48  ? 324.978 325.046 412.357 1.00 72.45  ? 48  LEU H CD2 1 
ATOM 2308 N N   . GLU C 2 49  ? 325.645 326.405 407.975 1.00 72.28  ? 49  GLU H N   1 
ATOM 2309 C CA  . GLU C 2 49  ? 325.653 326.347 406.521 1.00 72.28  ? 49  GLU H CA  1 
ATOM 2310 C C   . GLU C 2 49  ? 325.466 324.904 406.079 1.00 72.28  ? 49  GLU H C   1 
ATOM 2311 O O   . GLU C 2 49  ? 325.862 323.970 406.778 1.00 72.28  ? 49  GLU H O   1 
ATOM 2312 C CB  . GLU C 2 49  ? 326.951 326.910 405.934 1.00 72.28  ? 49  GLU H CB  1 
ATOM 2313 C CG  . GLU C 2 49  ? 327.000 328.425 405.893 1.00 72.28  ? 49  GLU H CG  1 
ATOM 2314 C CD  . GLU C 2 49  ? 327.719 328.950 404.667 1.00 72.28  ? 49  GLU H CD  1 
ATOM 2315 O OE1 . GLU C 2 49  ? 328.186 328.128 403.851 1.00 72.28  ? 49  GLU H OE1 1 
ATOM 2316 O OE2 . GLU C 2 49  ? 327.814 330.186 404.517 1.00 72.28  ? 49  GLU H OE2 1 
ATOM 2317 N N   . TRP C 2 50  ? 324.871 324.731 404.903 1.00 62.77  ? 50  TRP H N   1 
ATOM 2318 C CA  . TRP C 2 50  ? 324.509 323.420 404.382 1.00 62.77  ? 50  TRP H CA  1 
ATOM 2319 C C   . TRP C 2 50  ? 325.524 323.006 403.327 1.00 62.77  ? 50  TRP H C   1 
ATOM 2320 O O   . TRP C 2 50  ? 325.753 323.743 402.362 1.00 62.77  ? 50  TRP H O   1 
ATOM 2321 C CB  . TRP C 2 50  ? 323.100 323.449 403.793 1.00 62.77  ? 50  TRP H CB  1 
ATOM 2322 C CG  . TRP C 2 50  ? 322.521 322.103 403.485 1.00 62.77  ? 50  TRP H CG  1 
ATOM 2323 C CD1 . TRP C 2 50  ? 322.047 321.194 404.379 1.00 62.77  ? 50  TRP H CD1 1 
ATOM 2324 C CD2 . TRP C 2 50  ? 322.334 321.525 402.189 1.00 62.77  ? 50  TRP H CD2 1 
ATOM 2325 N NE1 . TRP C 2 50  ? 321.584 320.082 403.724 1.00 62.77  ? 50  TRP H NE1 1 
ATOM 2326 C CE2 . TRP C 2 50  ? 321.750 320.262 402.377 1.00 62.77  ? 50  TRP H CE2 1 
ATOM 2327 C CE3 . TRP C 2 50  ? 322.610 321.951 400.889 1.00 62.77  ? 50  TRP H CE3 1 
ATOM 2328 C CZ2 . TRP C 2 50  ? 321.436 319.423 401.316 1.00 62.77  ? 50  TRP H CZ2 1 
ATOM 2329 C CZ3 . TRP C 2 50  ? 322.297 321.118 399.840 1.00 62.77  ? 50  TRP H CZ3 1 
ATOM 2330 C CH2 . TRP C 2 50  ? 321.717 319.868 400.057 1.00 62.77  ? 50  TRP H CH2 1 
ATOM 2331 N N   . ILE C 2 51  ? 326.126 321.833 403.508 1.00 66.74  ? 51  ILE H N   1 
ATOM 2332 C CA  . ILE C 2 51  ? 327.113 321.330 402.560 1.00 66.74  ? 51  ILE H CA  1 
ATOM 2333 C C   . ILE C 2 51  ? 326.409 320.516 401.485 1.00 66.74  ? 51  ILE H C   1 
ATOM 2334 O O   . ILE C 2 51  ? 326.438 320.869 400.302 1.00 66.74  ? 51  ILE H O   1 
ATOM 2335 C CB  . ILE C 2 51  ? 328.186 320.480 403.260 1.00 66.74  ? 51  ILE H CB  1 
ATOM 2336 C CG1 . ILE C 2 51  ? 328.908 321.295 404.330 1.00 66.74  ? 51  ILE H CG1 1 
ATOM 2337 C CG2 . ILE C 2 51  ? 329.167 319.938 402.242 1.00 66.74  ? 51  ILE H CG2 1 
ATOM 2338 C CD1 . ILE C 2 51  ? 329.627 322.495 403.794 1.00 66.74  ? 51  ILE H CD1 1 
ATOM 2339 N N   . GLY C 2 52  ? 325.766 319.429 401.891 1.00 63.24  ? 52  GLY H N   1 
ATOM 2340 C CA  . GLY C 2 52  ? 325.086 318.571 400.940 1.00 63.24  ? 52  GLY H CA  1 
ATOM 2341 C C   . GLY C 2 52  ? 324.505 317.362 401.633 1.00 63.24  ? 52  GLY H C   1 
ATOM 2342 O O   . GLY C 2 52  ? 324.609 317.201 402.853 1.00 63.24  ? 52  GLY H O   1 
ATOM 2343 N N   . MET C 2 53  ? 323.890 316.503 400.827 1.00 61.64  ? 53  MET H N   1 
ATOM 2344 C CA  . MET C 2 53  ? 323.216 315.308 401.305 1.00 61.64  ? 53  MET H CA  1 
ATOM 2345 C C   . MET C 2 53  ? 323.601 314.125 400.431 1.00 61.64  ? 53  MET H C   1 
ATOM 2346 O O   . MET C 2 53  ? 323.967 314.292 399.266 1.00 61.64  ? 53  MET H O   1 
ATOM 2347 C CB  . MET C 2 53  ? 321.696 315.489 401.292 1.00 61.64  ? 53  MET H CB  1 
ATOM 2348 C CG  . MET C 2 53  ? 321.116 315.606 399.895 1.00 61.64  ? 53  MET H CG  1 
ATOM 2349 S SD  . MET C 2 53  ? 319.459 316.310 399.840 1.00 61.64  ? 53  MET H SD  1 
ATOM 2350 C CE  . MET C 2 53  ? 318.714 315.521 401.260 1.00 61.64  ? 53  MET H CE  1 
ATOM 2351 N N   . ILE C 2 54  ? 323.518 312.926 401.001 1.00 61.75  ? 54  ILE H N   1 
ATOM 2352 C CA  . ILE C 2 54  ? 323.828 311.701 400.277 1.00 61.75  ? 54  ILE H CA  1 
ATOM 2353 C C   . ILE C 2 54  ? 322.829 310.618 400.663 1.00 61.75  ? 54  ILE H C   1 
ATOM 2354 O O   . ILE C 2 54  ? 322.319 310.586 401.786 1.00 61.75  ? 54  ILE H O   1 
ATOM 2355 C CB  . ILE C 2 54  ? 325.278 311.236 400.533 1.00 61.75  ? 54  ILE H CB  1 
ATOM 2356 C CG1 . ILE C 2 54  ? 325.702 310.209 399.485 1.00 61.75  ? 54  ILE H CG1 1 
ATOM 2357 C CG2 . ILE C 2 54  ? 325.432 310.679 401.933 1.00 61.75  ? 54  ILE H CG2 1 
ATOM 2358 C CD1 . ILE C 2 54  ? 327.072 309.649 399.707 1.00 61.75  ? 54  ILE H CD1 1 
ATOM 2359 N N   . HIS C 2 55  ? 322.542 309.730 399.712 1.00 62.77  ? 55  HIS H N   1 
ATOM 2360 C CA  . HIS C 2 55  ? 321.602 308.643 399.920 1.00 62.77  ? 55  HIS H CA  1 
ATOM 2361 C C   . HIS C 2 55  ? 322.333 307.311 399.937 1.00 62.77  ? 55  HIS H C   1 
ATOM 2362 O O   . HIS C 2 55  ? 322.972 306.946 398.942 1.00 62.77  ? 55  HIS H O   1 
ATOM 2363 C CB  . HIS C 2 55  ? 320.533 308.636 398.827 1.00 62.77  ? 55  HIS H CB  1 
ATOM 2364 C CG  . HIS C 2 55  ? 319.427 307.661 399.074 1.00 62.77  ? 55  HIS H CG  1 
ATOM 2365 N ND1 . HIS C 2 55  ? 318.713 307.632 400.252 1.00 62.77  ? 55  HIS H ND1 1 
ATOM 2366 C CD2 . HIS C 2 55  ? 318.903 306.690 398.291 1.00 62.77  ? 55  HIS H CD2 1 
ATOM 2367 C CE1 . HIS C 2 55  ? 317.802 306.678 400.188 1.00 62.77  ? 55  HIS H CE1 1 
ATOM 2368 N NE2 . HIS C 2 55  ? 317.897 306.092 399.008 1.00 62.77  ? 55  HIS H NE2 1 
ATOM 2369 N N   . PRO C 2 56  ? 322.272 306.571 401.046 1.00 68.42  ? 56  PRO H N   1 
ATOM 2370 C CA  . PRO C 2 56  ? 323.051 305.326 401.147 1.00 68.42  ? 56  PRO H CA  1 
ATOM 2371 C C   . PRO C 2 56  ? 322.727 304.279 400.093 1.00 68.42  ? 56  PRO H C   1 
ATOM 2372 O O   . PRO C 2 56  ? 323.612 303.493 399.738 1.00 68.42  ? 56  PRO H O   1 
ATOM 2373 C CB  . PRO C 2 56  ? 322.706 304.831 402.555 1.00 68.42  ? 56  PRO H CB  1 
ATOM 2374 C CG  . PRO C 2 56  ? 322.410 306.069 403.313 1.00 68.42  ? 56  PRO H CG  1 
ATOM 2375 C CD  . PRO C 2 56  ? 321.738 306.997 402.348 1.00 68.42  ? 56  PRO H CD  1 
ATOM 2376 N N   . ASP C 2 57  ? 321.487 304.223 399.600 1.00 71.03  ? 57  ASP H N   1 
ATOM 2377 C CA  . ASP C 2 57  ? 321.117 303.183 398.641 1.00 71.03  ? 57  ASP H CA  1 
ATOM 2378 C C   . ASP C 2 57  ? 322.023 303.212 397.421 1.00 71.03  ? 57  ASP H C   1 
ATOM 2379 O O   . ASP C 2 57  ? 322.807 302.286 397.188 1.00 71.03  ? 57  ASP H O   1 
ATOM 2380 C CB  . ASP C 2 57  ? 319.663 303.359 398.211 1.00 71.03  ? 57  ASP H CB  1 
ATOM 2381 C CG  . ASP C 2 57  ? 318.697 303.069 399.323 1.00 71.03  ? 57  ASP H CG  1 
ATOM 2382 O OD1 . ASP C 2 57  ? 319.044 302.244 400.182 1.00 71.03  ? 57  ASP H OD1 1 
ATOM 2383 O OD2 . ASP C 2 57  ? 317.599 303.665 399.342 1.00 71.03  ? 57  ASP H OD2 1 
ATOM 2384 N N   . SER C 2 58  ? 321.926 304.274 396.631 1.00 68.00  ? 58  SER H N   1 
ATOM 2385 C CA  . SER C 2 58  ? 322.854 304.545 395.544 1.00 68.00  ? 58  SER H CA  1 
ATOM 2386 C C   . SER C 2 58  ? 323.369 305.954 395.758 1.00 68.00  ? 58  SER H C   1 
ATOM 2387 O O   . SER C 2 58  ? 322.598 306.838 396.144 1.00 68.00  ? 58  SER H O   1 
ATOM 2388 C CB  . SER C 2 58  ? 322.175 304.412 394.180 1.00 68.00  ? 58  SER H CB  1 
ATOM 2389 O OG  . SER C 2 58  ? 323.069 304.756 393.136 1.00 68.00  ? 58  SER H OG  1 
ATOM 2390 N N   . GLY C 2 59  ? 324.661 306.166 395.523 1.00 65.99  ? 59  GLY H N   1 
ATOM 2391 C CA  . GLY C 2 59  ? 325.246 307.467 395.764 1.00 65.99  ? 59  GLY H CA  1 
ATOM 2392 C C   . GLY C 2 59  ? 324.509 308.514 394.958 1.00 65.99  ? 59  GLY H C   1 
ATOM 2393 O O   . GLY C 2 59  ? 324.707 308.622 393.736 1.00 65.99  ? 59  GLY H O   1 
ATOM 2394 N N   . THR C 2 60  ? 323.662 309.296 395.622 1.00 63.10  ? 60  THR H N   1 
ATOM 2395 C CA  . THR C 2 60  ? 322.835 310.304 394.975 1.00 63.10  ? 60  THR H CA  1 
ATOM 2396 C C   . THR C 2 60  ? 323.010 311.598 395.761 1.00 63.10  ? 60  THR H C   1 
ATOM 2397 O O   . THR C 2 60  ? 322.235 311.913 396.664 1.00 63.10  ? 60  THR H O   1 
ATOM 2398 C CB  . THR C 2 60  ? 321.371 309.871 394.916 1.00 63.10  ? 60  THR H CB  1 
ATOM 2399 O OG1 . THR C 2 60  ? 321.288 308.537 394.401 1.00 63.10  ? 60  THR H OG1 1 
ATOM 2400 C CG2 . THR C 2 60  ? 320.582 310.796 394.015 1.00 63.10  ? 60  THR H CG2 1 
ATOM 2401 N N   . THR C 2 61  ? 324.043 312.349 395.409 1.00 63.95  ? 61  THR H N   1 
ATOM 2402 C CA  . THR C 2 61  ? 324.405 313.508 396.198 1.00 63.95  ? 61  THR H CA  1 
ATOM 2403 C C   . THR C 2 61  ? 323.710 314.760 395.681 1.00 63.95  ? 61  THR H C   1 
ATOM 2404 O O   . THR C 2 61  ? 323.293 314.847 394.523 1.00 63.95  ? 61  THR H O   1 
ATOM 2405 C CB  . THR C 2 61  ? 325.917 313.710 396.184 1.00 63.95  ? 61  THR H CB  1 
ATOM 2406 O OG1 . THR C 2 61  ? 326.344 314.021 394.853 1.00 63.95  ? 61  THR H OG1 1 
ATOM 2407 C CG2 . THR C 2 61  ? 326.619 312.452 396.652 1.00 63.95  ? 61  THR H CG2 1 
ATOM 2408 N N   . ASN C 2 62  ? 323.576 315.732 396.573 1.00 65.28  ? 62  ASN H N   1 
ATOM 2409 C CA  . ASN C 2 62  ? 323.160 317.078 396.224 1.00 65.28  ? 62  ASN H CA  1 
ATOM 2410 C C   . ASN C 2 62  ? 324.130 318.050 396.870 1.00 65.28  ? 62  ASN H C   1 
ATOM 2411 O O   . ASN C 2 62  ? 324.655 317.791 397.954 1.00 65.28  ? 62  ASN H O   1 
ATOM 2412 C CB  . ASN C 2 62  ? 321.731 317.367 396.678 1.00 65.28  ? 62  ASN H CB  1 
ATOM 2413 C CG  . ASN C 2 62  ? 320.701 316.885 395.683 1.00 65.28  ? 62  ASN H CG  1 
ATOM 2414 O OD1 . ASN C 2 62  ? 320.942 316.884 394.478 1.00 65.28  ? 62  ASN H OD1 1 
ATOM 2415 N ND2 . ASN C 2 62  ? 319.544 316.468 396.182 1.00 65.28  ? 62  ASN H ND2 1 
ATOM 2416 N N   . TYR C 2 63  ? 324.380 319.165 396.195 1.00 69.40  ? 63  TYR H N   1 
ATOM 2417 C CA  . TYR C 2 63  ? 325.405 320.097 396.631 1.00 69.40  ? 63  TYR H CA  1 
ATOM 2418 C C   . TYR C 2 63  ? 324.887 321.525 396.571 1.00 69.40  ? 63  TYR H C   1 
ATOM 2419 O O   . TYR C 2 63  ? 323.928 321.839 395.862 1.00 69.40  ? 63  TYR H O   1 
ATOM 2420 C CB  . TYR C 2 63  ? 326.672 319.956 395.788 1.00 69.40  ? 63  TYR H CB  1 
ATOM 2421 C CG  . TYR C 2 63  ? 327.456 318.701 396.081 1.00 69.40  ? 63  TYR H CG  1 
ATOM 2422 C CD1 . TYR C 2 63  ? 328.080 318.522 397.304 1.00 69.40  ? 63  TYR H CD1 1 
ATOM 2423 C CD2 . TYR C 2 63  ? 327.572 317.696 395.135 1.00 69.40  ? 63  TYR H CD2 1 
ATOM 2424 C CE1 . TYR C 2 63  ? 328.797 317.378 397.578 1.00 69.40  ? 63  TYR H CE1 1 
ATOM 2425 C CE2 . TYR C 2 63  ? 328.287 316.549 395.400 1.00 69.40  ? 63  TYR H CE2 1 
ATOM 2426 C CZ  . TYR C 2 63  ? 328.897 316.396 396.623 1.00 69.40  ? 63  TYR H CZ  1 
ATOM 2427 O OH  . TYR C 2 63  ? 329.610 315.253 396.890 1.00 69.40  ? 63  TYR H OH  1 
ATOM 2428 N N   . ASN C 2 64  ? 325.554 322.391 397.332 1.00 69.08  ? 64  ASN H N   1 
ATOM 2429 C CA  . ASN C 2 64  ? 325.137 323.774 397.514 1.00 69.08  ? 64  ASN H CA  1 
ATOM 2430 C C   . ASN C 2 64  ? 325.395 324.645 396.290 1.00 69.08  ? 64  ASN H C   1 
ATOM 2431 O O   . ASN C 2 64  ? 324.991 325.812 396.299 1.00 69.08  ? 64  ASN H O   1 
ATOM 2432 C CB  . ASN C 2 64  ? 325.867 324.359 398.724 1.00 69.08  ? 64  ASN H CB  1 
ATOM 2433 C CG  . ASN C 2 64  ? 325.050 325.394 399.462 1.00 69.08  ? 64  ASN H CG  1 
ATOM 2434 O OD1 . ASN C 2 64  ? 324.671 326.422 398.905 1.00 69.08  ? 64  ASN H OD1 1 
ATOM 2435 N ND2 . ASN C 2 64  ? 324.781 325.133 400.733 1.00 69.08  ? 64  ASN H ND2 1 
ATOM 2436 N N   . GLU C 2 65  ? 326.080 324.116 395.268 1.00 76.36  ? 65  GLU H N   1 
ATOM 2437 C CA  . GLU C 2 65  ? 326.633 324.865 394.137 1.00 76.36  ? 65  GLU H CA  1 
ATOM 2438 C C   . GLU C 2 65  ? 327.832 325.660 394.637 1.00 76.36  ? 65  GLU H C   1 
ATOM 2439 O O   . GLU C 2 65  ? 328.592 326.243 393.859 1.00 76.36  ? 65  GLU H O   1 
ATOM 2440 C CB  . GLU C 2 65  ? 325.582 325.767 393.479 1.00 76.36  ? 65  GLU H CB  1 
ATOM 2441 C CG  . GLU C 2 65  ? 325.982 326.330 392.127 1.00 76.36  ? 65  GLU H CG  1 
ATOM 2442 C CD  . GLU C 2 65  ? 326.569 327.722 392.231 1.00 76.36  ? 65  GLU H CD  1 
ATOM 2443 O OE1 . GLU C 2 65  ? 326.195 328.457 393.169 1.00 76.36  ? 65  GLU H OE1 1 
ATOM 2444 O OE2 . GLU C 2 65  ? 327.407 328.081 391.378 1.00 76.36  ? 65  GLU H OE2 1 
ATOM 2445 N N   . LYS C 2 66  ? 328.004 325.655 395.950 1.00 76.60  ? 66  LYS H N   1 
ATOM 2446 C CA  . LYS C 2 66  ? 329.225 325.991 396.654 1.00 76.60  ? 66  LYS H CA  1 
ATOM 2447 C C   . LYS C 2 66  ? 329.665 324.730 397.384 1.00 76.60  ? 66  LYS H C   1 
ATOM 2448 O O   . LYS C 2 66  ? 328.848 323.852 397.672 1.00 76.60  ? 66  LYS H O   1 
ATOM 2449 C CB  . LYS C 2 66  ? 328.988 327.154 397.623 1.00 76.60  ? 66  LYS H CB  1 
ATOM 2450 C CG  . LYS C 2 66  ? 330.179 327.569 398.457 1.00 76.60  ? 66  LYS H CG  1 
ATOM 2451 C CD  . LYS C 2 66  ? 329.851 328.829 399.234 1.00 76.60  ? 66  LYS H CD  1 
ATOM 2452 C CE  . LYS C 2 66  ? 328.735 328.579 400.232 1.00 76.60  ? 66  LYS H CE  1 
ATOM 2453 N NZ  . LYS C 2 66  ? 328.416 329.793 401.028 1.00 76.60  ? 66  LYS H NZ  1 
ATOM 2454 N N   . PHE C 2 67  ? 330.966 324.625 397.646 1.00 78.62  ? 67  PHE H N   1 
ATOM 2455 C CA  . PHE C 2 67  ? 331.608 323.409 398.137 1.00 78.62  ? 67  PHE H CA  1 
ATOM 2456 C C   . PHE C 2 67  ? 331.625 322.309 397.084 1.00 78.62  ? 67  PHE H C   1 
ATOM 2457 O O   . PHE C 2 67  ? 331.855 321.143 397.425 1.00 78.62  ? 67  PHE H O   1 
ATOM 2458 C CB  . PHE C 2 67  ? 330.945 322.854 399.406 1.00 78.62  ? 67  PHE H CB  1 
ATOM 2459 C CG  . PHE C 2 67  ? 330.812 323.853 400.515 1.00 78.62  ? 67  PHE H CG  1 
ATOM 2460 C CD1 . PHE C 2 67  ? 331.869 324.113 401.365 1.00 78.62  ? 67  PHE H CD1 1 
ATOM 2461 C CD2 . PHE C 2 67  ? 329.618 324.522 400.715 1.00 78.62  ? 67  PHE H CD2 1 
ATOM 2462 C CE1 . PHE C 2 67  ? 331.741 325.028 402.389 1.00 78.62  ? 67  PHE H CE1 1 
ATOM 2463 C CE2 . PHE C 2 67  ? 329.485 325.436 401.734 1.00 78.62  ? 67  PHE H CE2 1 
ATOM 2464 C CZ  . PHE C 2 67  ? 330.546 325.690 402.573 1.00 78.62  ? 67  PHE H CZ  1 
ATOM 2465 N N   . LYS C 2 68  ? 331.361 322.641 395.817 1.00 81.57  ? 68  LYS H N   1 
ATOM 2466 C CA  . LYS C 2 68  ? 331.415 321.638 394.758 1.00 81.57  ? 68  LYS H CA  1 
ATOM 2467 C C   . LYS C 2 68  ? 332.797 321.006 394.674 1.00 81.57  ? 68  LYS H C   1 
ATOM 2468 O O   . LYS C 2 68  ? 332.936 319.778 394.699 1.00 81.57  ? 68  LYS H O   1 
ATOM 2469 C CB  . LYS C 2 68  ? 331.044 322.268 393.417 1.00 81.57  ? 68  LYS H CB  1 
ATOM 2470 C CG  . LYS C 2 68  ? 329.640 322.821 393.340 1.00 81.57  ? 68  LYS H CG  1 
ATOM 2471 C CD  . LYS C 2 68  ? 328.622 321.717 393.507 1.00 81.57  ? 68  LYS H CD  1 
ATOM 2472 C CE  . LYS C 2 68  ? 328.670 320.737 392.349 1.00 81.57  ? 68  LYS H CE  1 
ATOM 2473 N NZ  . LYS C 2 68  ? 328.273 321.371 391.063 1.00 81.57  ? 68  LYS H NZ  1 
ATOM 2474 N N   . SER C 2 69  ? 333.833 321.837 394.574 1.00 87.77  ? 69  SER H N   1 
ATOM 2475 C CA  . SER C 2 69  ? 335.195 321.328 394.489 1.00 87.77  ? 69  SER H CA  1 
ATOM 2476 C C   . SER C 2 69  ? 335.738 320.932 395.855 1.00 87.77  ? 69  SER H C   1 
ATOM 2477 O O   . SER C 2 69  ? 336.501 319.967 395.966 1.00 87.77  ? 69  SER H O   1 
ATOM 2478 C CB  . SER C 2 69  ? 336.101 322.375 393.843 1.00 87.77  ? 69  SER H CB  1 
ATOM 2479 O OG  . SER C 2 69  ? 336.159 323.547 394.637 1.00 87.77  ? 69  SER H OG  1 
ATOM 2480 N N   . LYS C 2 70  ? 335.355 321.661 396.904 1.00 88.54  ? 70  LYS H N   1 
ATOM 2481 C CA  . LYS C 2 70  ? 335.975 321.456 398.208 1.00 88.54  ? 70  LYS H CA  1 
ATOM 2482 C C   . LYS C 2 70  ? 335.532 320.147 398.849 1.00 88.54  ? 70  LYS H C   1 
ATOM 2483 O O   . LYS C 2 70  ? 336.358 319.418 399.409 1.00 88.54  ? 70  LYS H O   1 
ATOM 2484 C CB  . LYS C 2 70  ? 335.665 322.635 399.126 1.00 88.54  ? 70  LYS H CB  1 
ATOM 2485 C CG  . LYS C 2 70  ? 336.361 323.917 398.716 1.00 88.54  ? 70  LYS H CG  1 
ATOM 2486 C CD  . LYS C 2 70  ? 336.133 325.023 399.727 1.00 88.54  ? 70  LYS H CD  1 
ATOM 2487 C CE  . LYS C 2 70  ? 336.896 326.276 399.336 1.00 88.54  ? 70  LYS H CE  1 
ATOM 2488 N NZ  . LYS C 2 70  ? 338.369 326.063 399.404 1.00 88.54  ? 70  LYS H NZ  1 
ATOM 2489 N N   . ALA C 2 71  ? 334.245 319.827 398.778 1.00 82.66  ? 71  ALA H N   1 
ATOM 2490 C CA  . ALA C 2 71  ? 333.691 318.689 399.497 1.00 82.66  ? 71  ALA H CA  1 
ATOM 2491 C C   . ALA C 2 71  ? 333.140 317.654 398.528 1.00 82.66  ? 71  ALA H C   1 
ATOM 2492 O O   . ALA C 2 71  ? 332.484 317.999 397.541 1.00 82.66  ? 71  ALA H O   1 
ATOM 2493 C CB  . ALA C 2 71  ? 332.588 319.133 400.460 1.00 82.66  ? 71  ALA H CB  1 
ATOM 2494 N N   . THR C 2 72  ? 333.418 316.385 398.816 1.00 79.50  ? 72  THR H N   1 
ATOM 2495 C CA  . THR C 2 72  ? 332.825 315.261 398.108 1.00 79.50  ? 72  THR H CA  1 
ATOM 2496 C C   . THR C 2 72  ? 332.354 314.238 399.129 1.00 79.50  ? 72  THR H C   1 
ATOM 2497 O O   . THR C 2 72  ? 332.982 314.059 400.177 1.00 79.50  ? 72  THR H O   1 
ATOM 2498 C CB  . THR C 2 72  ? 333.809 314.626 397.112 1.00 79.50  ? 72  THR H CB  1 
ATOM 2499 O OG1 . THR C 2 72  ? 333.129 313.641 396.326 1.00 79.50  ? 72  THR H OG1 1 
ATOM 2500 C CG2 . THR C 2 72  ? 334.974 313.977 397.830 1.00 79.50  ? 72  THR H CG2 1 
ATOM 2501 N N   . LEU C 2 73  ? 331.237 313.583 398.831 1.00 71.67  ? 73  LEU H N   1 
ATOM 2502 C CA  . LEU C 2 73  ? 330.560 312.710 399.780 1.00 71.67  ? 73  LEU H CA  1 
ATOM 2503 C C   . LEU C 2 73  ? 330.526 311.285 399.248 1.00 71.67  ? 73  LEU H C   1 
ATOM 2504 O O   . LEU C 2 73  ? 330.217 311.064 398.073 1.00 71.67  ? 73  LEU H O   1 
ATOM 2505 C CB  . LEU C 2 73  ? 329.135 313.197 400.048 1.00 71.67  ? 73  LEU H CB  1 
ATOM 2506 C CG  . LEU C 2 73  ? 328.927 314.257 401.128 1.00 71.67  ? 73  LEU H CG  1 
ATOM 2507 C CD1 . LEU C 2 73  ? 329.392 315.616 400.656 1.00 71.67  ? 73  LEU H CD1 1 
ATOM 2508 C CD2 . LEU C 2 73  ? 327.468 314.309 401.505 1.00 71.67  ? 73  LEU H CD2 1 
ATOM 2509 N N   . THR C 2 74  ? 330.848 310.328 400.114 1.00 73.38  ? 74  THR H N   1 
ATOM 2510 C CA  . THR C 2 74  ? 330.744 308.911 399.804 1.00 73.38  ? 74  THR H CA  1 
ATOM 2511 C C   . THR C 2 74  ? 330.271 308.171 401.045 1.00 73.38  ? 74  THR H C   1 
ATOM 2512 O O   . THR C 2 74  ? 330.482 308.623 402.173 1.00 73.38  ? 74  THR H O   1 
ATOM 2513 C CB  . THR C 2 74  ? 332.078 308.313 399.335 1.00 73.38  ? 74  THR H CB  1 
ATOM 2514 O OG1 . THR C 2 74  ? 333.127 308.721 400.222 1.00 73.38  ? 74  THR H OG1 1 
ATOM 2515 C CG2 . THR C 2 74  ? 332.408 308.756 397.918 1.00 73.38  ? 74  THR H CG2 1 
ATOM 2516 N N   . VAL C 2 75  ? 329.628 307.028 400.827 1.00 76.74  ? 75  VAL H N   1 
ATOM 2517 C CA  . VAL C 2 75  ? 329.177 306.166 401.912 1.00 76.74  ? 75  VAL H CA  1 
ATOM 2518 C C   . VAL C 2 75  ? 329.523 304.726 401.570 1.00 76.74  ? 75  VAL H C   1 
ATOM 2519 O O   . VAL C 2 75  ? 329.328 304.279 400.436 1.00 76.74  ? 75  VAL H O   1 
ATOM 2520 C CB  . VAL C 2 75  ? 327.663 306.304 402.176 1.00 76.74  ? 75  VAL H CB  1 
ATOM 2521 C CG1 . VAL C 2 75  ? 327.356 307.638 402.830 1.00 76.74  ? 75  VAL H CG1 1 
ATOM 2522 C CG2 . VAL C 2 75  ? 326.878 306.145 400.885 1.00 76.74  ? 75  VAL H CG2 1 
ATOM 2523 N N   . ASP C 2 76  ? 330.052 304.006 402.551 1.00 83.97  ? 76  ASP H N   1 
ATOM 2524 C CA  . ASP C 2 76  ? 330.180 302.564 402.434 1.00 83.97  ? 76  ASP H CA  1 
ATOM 2525 C C   . ASP C 2 76  ? 328.900 301.868 402.895 1.00 83.97  ? 76  ASP H C   1 
ATOM 2526 O O   . ASP C 2 76  ? 328.203 302.329 403.803 1.00 83.97  ? 76  ASP H O   1 
ATOM 2527 C CB  . ASP C 2 76  ? 331.449 302.086 403.162 1.00 83.97  ? 76  ASP H CB  1 
ATOM 2528 C CG  . ASP C 2 76  ? 331.346 302.109 404.689 1.00 83.97  ? 76  ASP H CG  1 
ATOM 2529 O OD1 . ASP C 2 76  ? 330.253 302.134 405.274 1.00 83.97  ? 76  ASP H OD1 1 
ATOM 2530 O OD2 . ASP C 2 76  ? 332.421 302.098 405.325 1.00 83.97  ? 76  ASP H OD2 1 
ATOM 2531 N N   . LYS C 2 77  ? 328.555 300.784 402.197 1.00 82.94  ? 77  LYS H N   1 
ATOM 2532 C CA  . LYS C 2 77  ? 327.233 300.187 402.368 1.00 82.94  ? 77  LYS H CA  1 
ATOM 2533 C C   . LYS C 2 77  ? 327.075 299.559 403.747 1.00 82.94  ? 77  LYS H C   1 
ATOM 2534 O O   . LYS C 2 77  ? 326.108 299.845 404.461 1.00 82.94  ? 77  LYS H O   1 
ATOM 2535 C CB  . LYS C 2 77  ? 326.983 299.154 401.270 1.00 82.94  ? 77  LYS H CB  1 
ATOM 2536 C CG  . LYS C 2 77  ? 325.552 298.650 401.214 1.00 82.94  ? 77  LYS H CG  1 
ATOM 2537 C CD  . LYS C 2 77  ? 324.579 299.785 400.942 1.00 82.94  ? 77  LYS H CD  1 
ATOM 2538 C CE  . LYS C 2 77  ? 324.820 300.405 399.577 1.00 82.94  ? 77  LYS H CE  1 
ATOM 2539 N NZ  . LYS C 2 77  ? 324.475 299.467 398.476 1.00 82.94  ? 77  LYS H NZ  1 
ATOM 2540 N N   . SER C 2 78  ? 328.017 298.711 404.142 1.00 87.58  ? 78  SER H N   1 
ATOM 2541 C CA  . SER C 2 78  ? 327.981 298.061 405.441 1.00 87.58  ? 78  SER H CA  1 
ATOM 2542 C C   . SER C 2 78  ? 328.871 298.824 406.415 1.00 87.58  ? 78  SER H C   1 
ATOM 2543 O O   . SER C 2 78  ? 329.528 299.799 406.053 1.00 87.58  ? 78  SER H O   1 
ATOM 2544 C CB  . SER C 2 78  ? 328.410 296.599 405.324 1.00 87.58  ? 78  SER H CB  1 
ATOM 2545 O OG  . SER C 2 78  ? 328.197 295.914 406.544 1.00 87.58  ? 78  SER H OG  1 
ATOM 2546 N N   . SER C 2 79  ? 328.879 298.373 407.671 1.00 87.54  ? 79  SER H N   1 
ATOM 2547 C CA  . SER C 2 79  ? 329.597 299.013 408.774 1.00 87.54  ? 79  SER H CA  1 
ATOM 2548 C C   . SER C 2 79  ? 328.959 300.346 409.149 1.00 87.54  ? 79  SER H C   1 
ATOM 2549 O O   . SER C 2 79  ? 329.418 301.015 410.080 1.00 87.54  ? 79  SER H O   1 
ATOM 2550 C CB  . SER C 2 79  ? 331.080 299.208 408.443 1.00 87.54  ? 79  SER H CB  1 
ATOM 2551 O OG  . SER C 2 79  ? 331.259 300.233 407.481 1.00 87.54  ? 79  SER H OG  1 
ATOM 2552 N N   . ASN C 2 80  ? 327.903 300.731 408.430 1.00 84.81  ? 80  ASN H N   1 
ATOM 2553 C CA  . ASN C 2 80  ? 327.066 301.880 408.772 1.00 84.81  ? 80  ASN H CA  1 
ATOM 2554 C C   . ASN C 2 80  ? 327.898 303.151 408.932 1.00 84.81  ? 80  ASN H C   1 
ATOM 2555 O O   . ASN C 2 80  ? 327.868 303.818 409.967 1.00 84.81  ? 80  ASN H O   1 
ATOM 2556 C CB  . ASN C 2 80  ? 326.266 301.598 410.042 1.00 84.81  ? 80  ASN H CB  1 
ATOM 2557 C CG  . ASN C 2 80  ? 325.195 300.551 409.833 1.00 84.81  ? 80  ASN H CG  1 
ATOM 2558 O OD1 . ASN C 2 80  ? 324.507 300.543 408.816 1.00 84.81  ? 80  ASN H OD1 1 
ATOM 2559 N ND2 . ASN C 2 80  ? 325.043 299.663 410.808 1.00 84.81  ? 80  ASN H ND2 1 
ATOM 2560 N N   . THR C 2 81  ? 328.648 303.489 407.888 1.00 82.90  ? 81  THR H N   1 
ATOM 2561 C CA  . THR C 2 81  ? 329.626 304.563 407.957 1.00 82.90  ? 81  THR H CA  1 
ATOM 2562 C C   . THR C 2 81  ? 329.430 305.533 406.799 1.00 82.90  ? 81  THR H C   1 
ATOM 2563 O O   . THR C 2 81  ? 329.099 305.131 405.681 1.00 82.90  ? 81  THR H O   1 
ATOM 2564 C CB  . THR C 2 81  ? 331.056 303.988 407.944 1.00 82.90  ? 81  THR H CB  1 
ATOM 2565 O OG1 . THR C 2 81  ? 331.231 303.123 409.073 1.00 82.90  ? 81  THR H OG1 1 
ATOM 2566 C CG2 . THR C 2 81  ? 332.095 305.087 408.004 1.00 82.90  ? 81  THR H CG2 1 
ATOM 2567 N N   . ALA C 2 82  ? 329.636 306.819 407.080 1.00 79.94  ? 82  ALA H N   1 
ATOM 2568 C CA  . ALA C 2 82  ? 329.587 307.871 406.076 1.00 79.94  ? 82  ALA H CA  1 
ATOM 2569 C C   . ALA C 2 82  ? 330.867 308.694 406.143 1.00 79.94  ? 82  ALA H C   1 
ATOM 2570 O O   . ALA C 2 82  ? 331.513 308.776 407.189 1.00 79.94  ? 82  ALA H O   1 
ATOM 2571 C CB  . ALA C 2 82  ? 328.368 308.776 406.272 1.00 79.94  ? 82  ALA H CB  1 
ATOM 2572 N N   . TYR C 2 83  ? 331.227 309.307 405.016 1.00 80.50  ? 83  TYR H N   1 
ATOM 2573 C CA  . TYR C 2 83  ? 332.483 310.034 404.890 1.00 80.50  ? 83  TYR H CA  1 
ATOM 2574 C C   . TYR C 2 83  ? 332.254 311.394 404.246 1.00 80.50  ? 83  TYR H C   1 
ATOM 2575 O O   . TYR C 2 83  ? 331.223 311.645 403.618 1.00 80.50  ? 83  TYR H O   1 
ATOM 2576 C CB  . TYR C 2 83  ? 333.511 309.253 404.064 1.00 80.50  ? 83  TYR H CB  1 
ATOM 2577 C CG  . TYR C 2 83  ? 333.795 307.863 404.577 1.00 80.50  ? 83  TYR H CG  1 
ATOM 2578 C CD1 . TYR C 2 83  ? 334.535 307.667 405.734 1.00 80.50  ? 83  TYR H CD1 1 
ATOM 2579 C CD2 . TYR C 2 83  ? 333.332 306.746 403.900 1.00 80.50  ? 83  TYR H CD2 1 
ATOM 2580 C CE1 . TYR C 2 83  ? 334.802 306.399 406.204 1.00 80.50  ? 83  TYR H CE1 1 
ATOM 2581 C CE2 . TYR C 2 83  ? 333.593 305.475 404.361 1.00 80.50  ? 83  TYR H CE2 1 
ATOM 2582 C CZ  . TYR C 2 83  ? 334.330 305.306 405.511 1.00 80.50  ? 83  TYR H CZ  1 
ATOM 2583 O OH  . TYR C 2 83  ? 334.589 304.037 405.973 1.00 80.50  ? 83  TYR H OH  1 
ATOM 2584 N N   . MET C 2 84  ? 333.243 312.274 404.416 1.00 81.14  ? 84  MET H N   1 
ATOM 2585 C CA  . MET C 2 84  ? 333.216 313.610 403.823 1.00 81.14  ? 84  MET H CA  1 
ATOM 2586 C C   . MET C 2 84  ? 334.658 314.036 403.560 1.00 81.14  ? 84  MET H C   1 
ATOM 2587 O O   . MET C 2 84  ? 335.350 314.483 404.478 1.00 81.14  ? 84  MET H O   1 
ATOM 2588 C CB  . MET C 2 84  ? 332.508 314.601 404.733 1.00 81.14  ? 84  MET H CB  1 
ATOM 2589 C CG  . MET C 2 84  ? 332.165 315.911 404.061 1.00 81.14  ? 84  MET H CG  1 
ATOM 2590 S SD  . MET C 2 84  ? 331.853 317.200 405.274 1.00 81.14  ? 84  MET H SD  1 
ATOM 2591 C CE  . MET C 2 84  ? 331.862 318.643 404.223 1.00 81.14  ? 84  MET H CE  1 
ATOM 2592 N N   . GLN C 2 85  ? 335.093 313.921 402.310 1.00 87.46  ? 85  GLN H N   1 
ATOM 2593 C CA  . GLN C 2 85  ? 336.458 314.260 401.931 1.00 87.46  ? 85  GLN H CA  1 
ATOM 2594 C C   . GLN C 2 85  ? 336.538 315.736 401.563 1.00 87.46  ? 85  GLN H C   1 
ATOM 2595 O O   . GLN C 2 85  ? 335.854 316.187 400.639 1.00 87.46  ? 85  GLN H O   1 
ATOM 2596 C CB  . GLN C 2 85  ? 336.921 313.394 400.762 1.00 87.46  ? 85  GLN H CB  1 
ATOM 2597 C CG  . GLN C 2 85  ? 338.420 313.405 400.532 1.00 87.46  ? 85  GLN H CG  1 
ATOM 2598 C CD  . GLN C 2 85  ? 339.148 312.416 401.416 1.00 87.46  ? 85  GLN H CD  1 
ATOM 2599 O OE1 . GLN C 2 85  ? 338.930 311.209 401.322 1.00 87.46  ? 85  GLN H OE1 1 
ATOM 2600 N NE2 . GLN C 2 85  ? 340.013 312.922 402.286 1.00 87.46  ? 85  GLN H NE2 1 
ATOM 2601 N N   . LEU C 2 86  ? 337.372 316.485 402.283 1.00 92.71  ? 86  LEU H N   1 
ATOM 2602 C CA  . LEU C 2 86  ? 337.644 317.885 401.973 1.00 92.71  ? 86  LEU H CA  1 
ATOM 2603 C C   . LEU C 2 86  ? 338.930 317.947 401.157 1.00 92.71  ? 86  LEU H C   1 
ATOM 2604 O O   . LEU C 2 86  ? 340.013 317.662 401.675 1.00 92.71  ? 86  LEU H O   1 
ATOM 2605 C CB  . LEU C 2 86  ? 337.759 318.717 403.248 1.00 92.71  ? 86  LEU H CB  1 
ATOM 2606 C CG  . LEU C 2 86  ? 336.480 318.898 404.064 1.00 92.71  ? 86  LEU H CG  1 
ATOM 2607 C CD1 . LEU C 2 86  ? 336.780 319.599 405.374 1.00 92.71  ? 86  LEU H CD1 1 
ATOM 2608 C CD2 . LEU C 2 86  ? 335.452 319.673 403.266 1.00 92.71  ? 86  LEU H CD2 1 
ATOM 2609 N N   . SER C 2 87  ? 338.808 318.320 399.881 1.00 97.88  ? 87  SER H N   1 
ATOM 2610 C CA  . SER C 2 87  ? 339.942 318.219 398.966 1.00 97.88  ? 87  SER H CA  1 
ATOM 2611 C C   . SER C 2 87  ? 341.078 319.148 399.376 1.00 97.88  ? 87  SER H C   1 
ATOM 2612 O O   . SER C 2 87  ? 342.226 318.714 399.527 1.00 97.88  ? 87  SER H O   1 
ATOM 2613 C CB  . SER C 2 87  ? 339.491 318.529 397.540 1.00 97.88  ? 87  SER H CB  1 
ATOM 2614 O OG  . SER C 2 87  ? 339.088 319.881 397.419 1.00 97.88  ? 87  SER H OG  1 
ATOM 2615 N N   . SER C 2 88  ? 340.779 320.431 399.563 1.00 102.96 ? 88  SER H N   1 
ATOM 2616 C CA  . SER C 2 88  ? 341.792 321.429 399.877 1.00 102.96 ? 88  SER H CA  1 
ATOM 2617 C C   . SER C 2 88  ? 341.397 322.159 401.149 1.00 102.96 ? 88  SER H C   1 
ATOM 2618 O O   . SER C 2 88  ? 340.262 322.628 401.271 1.00 102.96 ? 88  SER H O   1 
ATOM 2619 C CB  . SER C 2 88  ? 341.970 322.426 398.729 1.00 102.96 ? 88  SER H CB  1 
ATOM 2620 O OG  . SER C 2 88  ? 342.882 323.449 399.084 1.00 102.96 ? 88  SER H OG  1 
ATOM 2621 N N   . LEU C 2 89  ? 342.333 322.257 402.087 1.00 107.15 ? 89  LEU H N   1 
ATOM 2622 C CA  . LEU C 2 89  ? 342.098 322.907 403.372 1.00 107.15 ? 89  LEU H CA  1 
ATOM 2623 C C   . LEU C 2 89  ? 343.120 324.023 403.545 1.00 107.15 ? 89  LEU H C   1 
ATOM 2624 O O   . LEU C 2 89  ? 344.277 323.770 403.892 1.00 107.15 ? 89  LEU H O   1 
ATOM 2625 C CB  . LEU C 2 89  ? 342.175 321.905 404.518 1.00 107.15 ? 89  LEU H CB  1 
ATOM 2626 C CG  . LEU C 2 89  ? 340.953 321.008 404.708 1.00 107.15 ? 89  LEU H CG  1 
ATOM 2627 C CD1 . LEU C 2 89  ? 340.951 320.416 406.104 1.00 107.15 ? 89  LEU H CD1 1 
ATOM 2628 C CD2 . LEU C 2 89  ? 339.673 321.787 404.454 1.00 107.15 ? 89  LEU H CD2 1 
ATOM 2629 N N   . THR C 2 90  ? 342.689 325.260 403.306 1.00 110.67 ? 90  THR H N   1 
ATOM 2630 C CA  . THR C 2 90  ? 343.536 326.412 403.572 1.00 110.67 ? 90  THR H CA  1 
ATOM 2631 C C   . THR C 2 90  ? 343.582 326.764 405.051 1.00 110.67 ? 90  THR H C   1 
ATOM 2632 O O   . THR C 2 90  ? 344.312 327.689 405.424 1.00 110.67 ? 90  THR H O   1 
ATOM 2633 C CB  . THR C 2 90  ? 343.050 327.620 402.771 1.00 110.67 ? 90  THR H CB  1 
ATOM 2634 O OG1 . THR C 2 90  ? 341.869 328.154 403.380 1.00 110.67 ? 90  THR H OG1 1 
ATOM 2635 C CG2 . THR C 2 90  ? 342.734 327.215 401.341 1.00 110.67 ? 90  THR H CG2 1 
ATOM 2636 N N   . SER C 2 91  ? 342.794 326.077 405.883 1.00 108.83 ? 91  SER H N   1 
ATOM 2637 C CA  . SER C 2 91  ? 342.704 326.301 407.322 1.00 108.83 ? 91  SER H CA  1 
ATOM 2638 C C   . SER C 2 91  ? 342.064 327.650 407.631 1.00 108.83 ? 91  SER H C   1 
ATOM 2639 O O   . SER C 2 91  ? 341.844 327.986 408.799 1.00 108.83 ? 91  SER H O   1 
ATOM 2640 C CB  . SER C 2 91  ? 344.079 326.185 407.989 1.00 108.83 ? 91  SER H CB  1 
ATOM 2641 O OG  . SER C 2 91  ? 344.438 324.828 408.179 1.00 108.83 ? 91  SER H OG  1 
ATOM 2642 N N   . GLU C 2 92  ? 341.760 328.429 406.590 1.00 108.35 ? 92  GLU H N   1 
ATOM 2643 C CA  . GLU C 2 92  ? 340.923 329.607 406.772 1.00 108.35 ? 92  GLU H CA  1 
ATOM 2644 C C   . GLU C 2 92  ? 339.480 329.210 407.041 1.00 108.35 ? 92  GLU H C   1 
ATOM 2645 O O   . GLU C 2 92  ? 338.786 329.874 407.820 1.00 108.35 ? 92  GLU H O   1 
ATOM 2646 C CB  . GLU C 2 92  ? 341.015 330.510 405.541 1.00 108.35 ? 92  GLU H CB  1 
ATOM 2647 C CG  . GLU C 2 92  ? 340.019 331.660 405.522 1.00 108.35 ? 92  GLU H CG  1 
ATOM 2648 C CD  . GLU C 2 92  ? 338.792 331.356 404.686 1.00 108.35 ? 92  GLU H CD  1 
ATOM 2649 O OE1 . GLU C 2 92  ? 338.801 330.338 403.964 1.00 108.35 ? 92  GLU H OE1 1 
ATOM 2650 O OE2 . GLU C 2 92  ? 337.818 332.134 404.751 1.00 108.35 ? 92  GLU H OE2 1 
ATOM 2651 N N   . ASP C 2 93  ? 339.019 328.130 406.417 1.00 104.52 ? 93  ASP H N   1 
ATOM 2652 C CA  . ASP C 2 93  ? 337.672 327.609 406.639 1.00 104.52 ? 93  ASP H CA  1 
ATOM 2653 C C   . ASP C 2 93  ? 337.692 326.536 407.729 1.00 104.52 ? 93  ASP H C   1 
ATOM 2654 O O   . ASP C 2 93  ? 337.295 325.388 407.534 1.00 104.52 ? 93  ASP H O   1 
ATOM 2655 C CB  . ASP C 2 93  ? 337.097 327.075 405.333 1.00 104.52 ? 93  ASP H CB  1 
ATOM 2656 C CG  . ASP C 2 93  ? 338.011 326.069 404.658 1.00 104.52 ? 93  ASP H CG  1 
ATOM 2657 O OD1 . ASP C 2 93  ? 339.080 325.758 405.222 1.00 104.52 ? 93  ASP H OD1 1 
ATOM 2658 O OD2 . ASP C 2 93  ? 337.663 325.593 403.558 1.00 104.52 ? 93  ASP H OD2 1 
ATOM 2659 N N   . SER C 2 94  ? 338.182 326.937 408.898 1.00 100.06 ? 94  SER H N   1 
ATOM 2660 C CA  . SER C 2 94  ? 338.209 326.072 410.069 1.00 100.06 ? 94  SER H CA  1 
ATOM 2661 C C   . SER C 2 94  ? 336.884 326.212 410.806 1.00 100.06 ? 94  SER H C   1 
ATOM 2662 O O   . SER C 2 94  ? 336.479 327.325 411.155 1.00 100.06 ? 94  SER H O   1 
ATOM 2663 C CB  . SER C 2 94  ? 339.378 326.435 410.982 1.00 100.06 ? 94  SER H CB  1 
ATOM 2664 O OG  . SER C 2 94  ? 340.616 326.287 410.309 1.00 100.06 ? 94  SER H OG  1 
ATOM 2665 N N   . ALA C 2 95  ? 336.213 325.090 411.041 1.00 87.62  ? 95  ALA H N   1 
ATOM 2666 C CA  . ALA C 2 95  ? 334.880 325.116 411.624 1.00 87.62  ? 95  ALA H CA  1 
ATOM 2667 C C   . ALA C 2 95  ? 334.566 323.743 412.197 1.00 87.62  ? 95  ALA H C   1 
ATOM 2668 O O   . ALA C 2 95  ? 335.405 322.838 412.197 1.00 87.62  ? 95  ALA H O   1 
ATOM 2669 C CB  . ALA C 2 95  ? 333.837 325.535 410.588 1.00 87.62  ? 95  ALA H CB  1 
ATOM 2670 N N   . VAL C 2 96  ? 333.340 323.598 412.689 1.00 80.35  ? 96  VAL H N   1 
ATOM 2671 C CA  . VAL C 2 96  ? 332.843 322.341 413.233 1.00 80.35  ? 96  VAL H CA  1 
ATOM 2672 C C   . VAL C 2 96  ? 331.842 321.760 412.247 1.00 80.35  ? 96  VAL H C   1 
ATOM 2673 O O   . VAL C 2 96  ? 330.931 322.462 411.790 1.00 80.35  ? 96  VAL H O   1 
ATOM 2674 C CB  . VAL C 2 96  ? 332.201 322.546 414.613 1.00 80.35  ? 96  VAL H CB  1 
ATOM 2675 C CG1 . VAL C 2 96  ? 331.756 321.215 415.187 1.00 80.35  ? 96  VAL H CG1 1 
ATOM 2676 C CG2 . VAL C 2 96  ? 333.171 323.243 415.547 1.00 80.35  ? 96  VAL H CG2 1 
ATOM 2677 N N   . TYR C 2 97  ? 332.005 320.484 411.919 1.00 77.46  ? 97  TYR H N   1 
ATOM 2678 C CA  . TYR C 2 97  ? 331.191 319.817 410.914 1.00 77.46  ? 97  TYR H CA  1 
ATOM 2679 C C   . TYR C 2 97  ? 330.291 318.796 411.595 1.00 77.46  ? 97  TYR H C   1 
ATOM 2680 O O   . TYR C 2 97  ? 330.777 317.919 412.315 1.00 77.46  ? 97  TYR H O   1 
ATOM 2681 C CB  . TYR C 2 97  ? 332.072 319.140 409.867 1.00 77.46  ? 97  TYR H CB  1 
ATOM 2682 C CG  . TYR C 2 97  ? 332.868 320.107 409.025 1.00 77.46  ? 97  TYR H CG  1 
ATOM 2683 C CD1 . TYR C 2 97  ? 334.082 320.608 409.469 1.00 77.46  ? 97  TYR H CD1 1 
ATOM 2684 C CD2 . TYR C 2 97  ? 332.404 320.522 407.787 1.00 77.46  ? 97  TYR H CD2 1 
ATOM 2685 C CE1 . TYR C 2 97  ? 334.810 321.492 408.705 1.00 77.46  ? 97  TYR H CE1 1 
ATOM 2686 C CE2 . TYR C 2 97  ? 333.126 321.405 407.016 1.00 77.46  ? 97  TYR H CE2 1 
ATOM 2687 C CZ  . TYR C 2 97  ? 334.327 321.887 407.480 1.00 77.46  ? 97  TYR H CZ  1 
ATOM 2688 O OH  . TYR C 2 97  ? 335.047 322.769 406.711 1.00 77.46  ? 97  TYR H OH  1 
ATOM 2689 N N   . TYR C 2 98  ? 328.988 318.909 411.363 1.00 74.98  ? 98  TYR H N   1 
ATOM 2690 C CA  . TYR C 2 98  ? 328.009 317.969 411.886 1.00 74.98  ? 98  TYR H CA  1 
ATOM 2691 C C   . TYR C 2 98  ? 327.494 317.077 410.767 1.00 74.98  ? 98  TYR H C   1 
ATOM 2692 O O   . TYR C 2 98  ? 327.774 317.291 409.585 1.00 74.98  ? 98  TYR H O   1 
ATOM 2693 C CB  . TYR C 2 98  ? 326.838 318.697 412.552 1.00 74.98  ? 98  TYR H CB  1 
ATOM 2694 C CG  . TYR C 2 98  ? 327.236 319.789 413.510 1.00 74.98  ? 98  TYR H CG  1 
ATOM 2695 C CD1 . TYR C 2 98  ? 327.420 321.090 413.072 1.00 74.98  ? 98  TYR H CD1 1 
ATOM 2696 C CD2 . TYR C 2 98  ? 327.416 319.520 414.856 1.00 74.98  ? 98  TYR H CD2 1 
ATOM 2697 C CE1 . TYR C 2 98  ? 327.775 322.091 413.947 1.00 74.98  ? 98  TYR H CE1 1 
ATOM 2698 C CE2 . TYR C 2 98  ? 327.775 320.511 415.736 1.00 74.98  ? 98  TYR H CE2 1 
ATOM 2699 C CZ  . TYR C 2 98  ? 327.951 321.796 415.279 1.00 74.98  ? 98  TYR H CZ  1 
ATOM 2700 O OH  . TYR C 2 98  ? 328.309 322.791 416.156 1.00 74.98  ? 98  TYR H OH  1 
ATOM 2701 N N   . CYS C 2 99  ? 326.724 316.066 411.158 1.00 71.78  ? 99  CYS H N   1 
ATOM 2702 C CA  . CYS C 2 99  ? 326.123 315.135 410.209 1.00 71.78  ? 99  CYS H CA  1 
ATOM 2703 C C   . CYS C 2 99  ? 324.759 314.713 410.734 1.00 71.78  ? 99  CYS H C   1 
ATOM 2704 O O   . CYS C 2 99  ? 324.653 313.738 411.480 1.00 71.78  ? 99  CYS H O   1 
ATOM 2705 C CB  . CYS C 2 99  ? 327.029 313.927 409.982 1.00 71.78  ? 99  CYS H CB  1 
ATOM 2706 S SG  . CYS C 2 99  ? 327.575 313.108 411.492 1.00 71.78  ? 99  CYS H SG  1 
ATOM 2707 N N   . ALA C 2 100 ? 323.717 315.428 410.330 1.00 68.07  ? 100 ALA H N   1 
ATOM 2708 C CA  . ALA C 2 100 ? 322.358 315.130 410.754 1.00 68.07  ? 100 ALA H CA  1 
ATOM 2709 C C   . ALA C 2 100 ? 321.747 314.055 409.867 1.00 68.07  ? 100 ALA H C   1 
ATOM 2710 O O   . ALA C 2 100 ? 322.192 313.815 408.743 1.00 68.07  ? 100 ALA H O   1 
ATOM 2711 C CB  . ALA C 2 100 ? 321.491 316.388 410.720 1.00 68.07  ? 100 ALA H CB  1 
ATOM 2712 N N   . ARG C 2 101 ? 320.713 313.403 410.391 1.00 66.73  ? 101 ARG H N   1 
ATOM 2713 C CA  . ARG C 2 101 ? 319.976 312.382 409.656 1.00 66.73  ? 101 ARG H CA  1 
ATOM 2714 C C   . ARG C 2 101 ? 318.685 313.005 409.140 1.00 66.73  ? 101 ARG H C   1 
ATOM 2715 O O   . ARG C 2 101 ? 317.837 313.434 409.927 1.00 66.73  ? 101 ARG H O   1 
ATOM 2716 C CB  . ARG C 2 101 ? 319.687 311.172 410.540 1.00 66.73  ? 101 ARG H CB  1 
ATOM 2717 C CG  . ARG C 2 101 ? 318.966 310.051 409.819 1.00 66.73  ? 101 ARG H CG  1 
ATOM 2718 C CD  . ARG C 2 101 ? 318.203 309.168 410.784 1.00 66.73  ? 101 ARG H CD  1 
ATOM 2719 N NE  . ARG C 2 101 ? 317.141 309.893 411.467 1.00 66.73  ? 101 ARG H NE  1 
ATOM 2720 C CZ  . ARG C 2 101 ? 316.103 309.318 412.057 1.00 66.73  ? 101 ARG H CZ  1 
ATOM 2721 N NH1 . ARG C 2 101 ? 315.957 308.004 412.072 1.00 66.73  ? 101 ARG H NH1 1 
ATOM 2722 N NH2 . ARG C 2 101 ? 315.189 310.081 412.648 1.00 66.73  ? 101 ARG H NH2 1 
ATOM 2723 N N   . GLY C 2 102 ? 318.539 313.053 407.818 1.00 59.94  ? 102 GLY H N   1 
ATOM 2724 C CA  . GLY C 2 102 ? 317.376 313.688 407.225 1.00 59.94  ? 102 GLY H CA  1 
ATOM 2725 C C   . GLY C 2 102 ? 316.157 312.781 407.258 1.00 59.94  ? 102 GLY H C   1 
ATOM 2726 O O   . GLY C 2 102 ? 316.249 311.569 407.069 1.00 59.94  ? 102 GLY H O   1 
ATOM 2727 N N   . VAL C 2 103 ? 315.000 313.389 407.496 1.00 54.46  ? 103 VAL H N   1 
ATOM 2728 C CA  . VAL C 2 103 ? 313.729 312.683 407.549 1.00 54.46  ? 103 VAL H CA  1 
ATOM 2729 C C   . VAL C 2 103 ? 312.755 313.369 406.603 1.00 54.46  ? 103 VAL H C   1 
ATOM 2730 O O   . VAL C 2 103 ? 312.670 314.601 406.570 1.00 54.46  ? 103 VAL H O   1 
ATOM 2731 C CB  . VAL C 2 103 ? 313.174 312.629 408.987 1.00 54.46  ? 103 VAL H CB  1 
ATOM 2732 C CG1 . VAL C 2 103 ? 313.019 314.022 409.557 1.00 54.46  ? 103 VAL H CG1 1 
ATOM 2733 C CG2 . VAL C 2 103 ? 311.866 311.892 409.011 1.00 54.46  ? 103 VAL H CG2 1 
ATOM 2734 N N   . PHE C 2 104 ? 312.040 312.574 405.812 1.00 52.84  ? 104 PHE H N   1 
ATOM 2735 C CA  . PHE C 2 104 ? 311.205 313.106 404.740 1.00 52.84  ? 104 PHE H CA  1 
ATOM 2736 C C   . PHE C 2 104 ? 309.843 312.421 404.711 1.00 52.84  ? 104 PHE H C   1 
ATOM 2737 O O   . PHE C 2 104 ? 309.370 311.979 403.664 1.00 52.84  ? 104 PHE H O   1 
ATOM 2738 C CB  . PHE C 2 104 ? 311.901 312.959 403.391 1.00 52.84  ? 104 PHE H CB  1 
ATOM 2739 C CG  . PHE C 2 104 ? 312.907 314.033 403.106 1.00 52.84  ? 104 PHE H CG  1 
ATOM 2740 C CD1 . PHE C 2 104 ? 314.198 313.938 403.589 1.00 52.84  ? 104 PHE H CD1 1 
ATOM 2741 C CD2 . PHE C 2 104 ? 312.564 315.137 402.354 1.00 52.84  ? 104 PHE H CD2 1 
ATOM 2742 C CE1 . PHE C 2 104 ? 315.124 314.922 403.326 1.00 52.84  ? 104 PHE H CE1 1 
ATOM 2743 C CE2 . PHE C 2 104 ? 313.487 316.124 402.089 1.00 52.84  ? 104 PHE H CE2 1 
ATOM 2744 C CZ  . PHE C 2 104 ? 314.767 316.016 402.576 1.00 52.84  ? 104 PHE H CZ  1 
ATOM 2745 N N   . TYR C 2 105 ? 309.188 312.319 405.864 1.00 55.72  ? 105 TYR H N   1 
ATOM 2746 C CA  . TYR C 2 105 ? 307.832 311.795 405.873 1.00 55.72  ? 105 TYR H CA  1 
ATOM 2747 C C   . TYR C 2 105 ? 306.872 312.828 405.292 1.00 55.72  ? 105 TYR H C   1 
ATOM 2748 O O   . TYR C 2 105 ? 307.256 313.942 404.929 1.00 55.72  ? 105 TYR H O   1 
ATOM 2749 C CB  . TYR C 2 105 ? 307.402 311.397 407.281 1.00 55.72  ? 105 TYR H CB  1 
ATOM 2750 C CG  . TYR C 2 105 ? 308.366 310.495 408.006 1.00 55.72  ? 105 TYR H CG  1 
ATOM 2751 C CD1 . TYR C 2 105 ? 309.048 309.494 407.335 1.00 55.72  ? 105 TYR H CD1 1 
ATOM 2752 C CD2 . TYR C 2 105 ? 308.555 310.613 409.373 1.00 55.72  ? 105 TYR H CD2 1 
ATOM 2753 C CE1 . TYR C 2 105 ? 309.922 308.664 407.998 1.00 55.72  ? 105 TYR H CE1 1 
ATOM 2754 C CE2 . TYR C 2 105 ? 309.419 309.780 410.046 1.00 55.72  ? 105 TYR H CE2 1 
ATOM 2755 C CZ  . TYR C 2 105 ? 310.100 308.807 409.353 1.00 55.72  ? 105 TYR H CZ  1 
ATOM 2756 O OH  . TYR C 2 105 ? 310.967 307.975 410.019 1.00 55.72  ? 105 TYR H OH  1 
ATOM 2757 N N   . ILE C 2 106 ? 305.595 312.458 405.210 1.00 54.09  ? 106 ILE H N   1 
ATOM 2758 C CA  . ILE C 2 106 ? 304.591 313.362 404.668 1.00 54.09  ? 106 ILE H CA  1 
ATOM 2759 C C   . ILE C 2 106 ? 304.304 314.460 405.681 1.00 54.09  ? 106 ILE H C   1 
ATOM 2760 O O   . ILE C 2 106 ? 304.008 314.187 406.852 1.00 54.09  ? 106 ILE H O   1 
ATOM 2761 C CB  . ILE C 2 106 ? 303.319 312.588 404.292 1.00 54.09  ? 106 ILE H CB  1 
ATOM 2762 C CG1 . ILE C 2 106 ? 302.195 313.550 403.921 1.00 54.09  ? 106 ILE H CG1 1 
ATOM 2763 C CG2 . ILE C 2 106 ? 302.894 311.664 405.418 1.00 54.09  ? 106 ILE H CG2 1 
ATOM 2764 C CD1 . ILE C 2 106 ? 301.040 312.877 403.230 1.00 54.09  ? 106 ILE H CD1 1 
ATOM 2765 N N   . ASN C 2 107 ? 304.408 315.713 405.236 1.00 55.74  ? 107 ASN H N   1 
ATOM 2766 C CA  . ASN C 2 107 ? 304.229 316.882 406.097 1.00 55.74  ? 107 ASN H CA  1 
ATOM 2767 C C   . ASN C 2 107 ? 305.193 316.860 407.279 1.00 55.74  ? 107 ASN H C   1 
ATOM 2768 O O   . ASN C 2 107 ? 304.879 317.356 408.362 1.00 55.74  ? 107 ASN H O   1 
ATOM 2769 C CB  . ASN C 2 107 ? 302.783 316.995 406.585 1.00 55.74  ? 107 ASN H CB  1 
ATOM 2770 C CG  . ASN C 2 107 ? 301.852 317.524 405.517 1.00 55.74  ? 107 ASN H CG  1 
ATOM 2771 O OD1 . ASN C 2 107 ? 302.195 318.446 404.781 1.00 55.74  ? 107 ASN H OD1 1 
ATOM 2772 N ND2 . ASN C 2 107 ? 300.666 316.939 405.424 1.00 55.74  ? 107 ASN H ND2 1 
ATOM 2773 N N   . TYR C 2 108 ? 306.374 316.279 407.074 1.00 56.32  ? 108 TYR H N   1 
ATOM 2774 C CA  . TYR C 2 108 ? 307.377 316.136 408.130 1.00 56.32  ? 108 TYR H CA  1 
ATOM 2775 C C   . TYR C 2 108 ? 308.742 316.221 407.448 1.00 56.32  ? 108 TYR H C   1 
ATOM 2776 O O   . TYR C 2 108 ? 309.290 315.209 407.006 1.00 56.32  ? 108 TYR H O   1 
ATOM 2777 C CB  . TYR C 2 108 ? 307.199 314.817 408.868 1.00 56.32  ? 108 TYR H CB  1 
ATOM 2778 C CG  . TYR C 2 108 ? 308.038 314.656 410.112 1.00 56.32  ? 108 TYR H CG  1 
ATOM 2779 C CD1 . TYR C 2 108 ? 307.625 315.182 411.319 1.00 56.32  ? 108 TYR H CD1 1 
ATOM 2780 C CD2 . TYR C 2 108 ? 309.242 313.979 410.079 1.00 56.32  ? 108 TYR H CD2 1 
ATOM 2781 C CE1 . TYR C 2 108 ? 308.381 315.040 412.460 1.00 56.32  ? 108 TYR H CE1 1 
ATOM 2782 C CE2 . TYR C 2 108 ? 310.006 313.831 411.217 1.00 56.32  ? 108 TYR H CE2 1 
ATOM 2783 C CZ  . TYR C 2 108 ? 309.572 314.363 412.403 1.00 56.32  ? 108 TYR H CZ  1 
ATOM 2784 O OH  . TYR C 2 108 ? 310.334 314.217 413.537 1.00 56.32  ? 108 TYR H OH  1 
ATOM 2785 N N   . TYR C 2 109 ? 309.281 317.433 407.370 1.00 52.88  ? 109 TYR H N   1 
ATOM 2786 C CA  . TYR C 2 109 ? 310.562 317.694 406.723 1.00 52.88  ? 109 TYR H CA  1 
ATOM 2787 C C   . TYR C 2 109 ? 311.471 318.377 407.730 1.00 52.88  ? 109 TYR H C   1 
ATOM 2788 O O   . TYR C 2 109 ? 311.179 319.496 408.166 1.00 52.88  ? 109 TYR H O   1 
ATOM 2789 C CB  . TYR C 2 109 ? 310.392 318.579 405.487 1.00 52.88  ? 109 TYR H CB  1 
ATOM 2790 C CG  . TYR C 2 109 ? 309.951 317.869 404.229 1.00 52.88  ? 109 TYR H CG  1 
ATOM 2791 C CD1 . TYR C 2 109 ? 309.069 316.806 404.277 1.00 52.88  ? 109 TYR H CD1 1 
ATOM 2792 C CD2 . TYR C 2 109 ? 310.412 318.276 402.988 1.00 52.88  ? 109 TYR H CD2 1 
ATOM 2793 C CE1 . TYR C 2 109 ? 308.663 316.164 403.128 1.00 52.88  ? 109 TYR H CE1 1 
ATOM 2794 C CE2 . TYR C 2 109 ? 310.013 317.639 401.835 1.00 52.88  ? 109 TYR H CE2 1 
ATOM 2795 C CZ  . TYR C 2 109 ? 309.137 316.585 401.911 1.00 52.88  ? 109 TYR H CZ  1 
ATOM 2796 O OH  . TYR C 2 109 ? 308.734 315.944 400.764 1.00 52.88  ? 109 TYR H OH  1 
ATOM 2797 N N   . ALA C 2 110 ? 312.571 317.722 408.087 1.00 56.87  ? 110 ALA H N   1 
ATOM 2798 C CA  . ALA C 2 110 ? 313.466 318.257 409.105 1.00 56.87  ? 110 ALA H CA  1 
ATOM 2799 C C   . ALA C 2 110 ? 314.748 317.441 409.117 1.00 56.87  ? 110 ALA H C   1 
ATOM 2800 O O   . ALA C 2 110 ? 314.878 316.439 408.410 1.00 56.87  ? 110 ALA H O   1 
ATOM 2801 C CB  . ALA C 2 110 ? 312.812 318.242 410.486 1.00 56.87  ? 110 ALA H CB  1 
ATOM 2802 N N   . MET C 2 111 ? 315.702 317.894 409.926 1.00 64.87  ? 111 MET H N   1 
ATOM 2803 C CA  . MET C 2 111 ? 316.894 317.126 410.260 1.00 64.87  ? 111 MET H CA  1 
ATOM 2804 C C   . MET C 2 111 ? 316.891 316.891 411.762 1.00 64.87  ? 111 MET H C   1 
ATOM 2805 O O   . MET C 2 111 ? 316.895 317.848 412.542 1.00 64.87  ? 111 MET H O   1 
ATOM 2806 C CB  . MET C 2 111 ? 318.177 317.845 409.845 1.00 64.87  ? 111 MET H CB  1 
ATOM 2807 C CG  . MET C 2 111 ? 318.370 318.005 408.358 1.00 64.87  ? 111 MET H CG  1 
ATOM 2808 S SD  . MET C 2 111 ? 319.944 318.797 407.990 1.00 64.87  ? 111 MET H SD  1 
ATOM 2809 C CE  . MET C 2 111 ? 319.615 320.486 408.457 1.00 64.87  ? 111 MET H CE  1 
ATOM 2810 N N   . ASP C 2 112 ? 316.893 315.627 412.165 1.00 69.57  ? 112 ASP H N   1 
ATOM 2811 C CA  . ASP C 2 112 ? 316.889 315.263 413.571 1.00 69.57  ? 112 ASP H CA  1 
ATOM 2812 C C   . ASP C 2 112 ? 318.062 314.338 413.860 1.00 69.57  ? 112 ASP H C   1 
ATOM 2813 O O   . ASP C 2 112 ? 318.642 313.737 412.952 1.00 69.57  ? 112 ASP H O   1 
ATOM 2814 C CB  . ASP C 2 112 ? 315.560 314.610 413.970 1.00 69.57  ? 112 ASP H CB  1 
ATOM 2815 C CG  . ASP C 2 112 ? 315.193 313.445 413.077 1.00 69.57  ? 112 ASP H CG  1 
ATOM 2816 O OD1 . ASP C 2 112 ? 315.919 313.190 412.096 1.00 69.57  ? 112 ASP H OD1 1 
ATOM 2817 O OD2 . ASP C 2 112 ? 314.171 312.784 413.353 1.00 69.57  ? 112 ASP H OD2 1 
ATOM 2818 N N   . TYR C 2 113 ? 318.414 314.244 415.142 1.00 71.64  ? 113 TYR H N   1 
ATOM 2819 C CA  . TYR C 2 113 ? 319.557 313.454 415.597 1.00 71.64  ? 113 TYR H CA  1 
ATOM 2820 C C   . TYR C 2 113 ? 320.850 313.942 414.942 1.00 71.64  ? 113 TYR H C   1 
ATOM 2821 O O   . TYR C 2 113 ? 321.497 313.235 414.168 1.00 71.64  ? 113 TYR H O   1 
ATOM 2822 C CB  . TYR C 2 113 ? 319.326 311.962 415.338 1.00 71.64  ? 113 TYR H CB  1 
ATOM 2823 C CG  . TYR C 2 113 ? 318.075 311.430 415.992 1.00 71.64  ? 113 TYR H CG  1 
ATOM 2824 C CD1 . TYR C 2 113 ? 317.925 311.460 417.370 1.00 71.64  ? 113 TYR H CD1 1 
ATOM 2825 C CD2 . TYR C 2 113 ? 317.043 310.902 415.233 1.00 71.64  ? 113 TYR H CD2 1 
ATOM 2826 C CE1 . TYR C 2 113 ? 316.785 310.978 417.973 1.00 71.64  ? 113 TYR H CE1 1 
ATOM 2827 C CE2 . TYR C 2 113 ? 315.898 310.415 415.828 1.00 71.64  ? 113 TYR H CE2 1 
ATOM 2828 C CZ  . TYR C 2 113 ? 315.774 310.456 417.198 1.00 71.64  ? 113 TYR H CZ  1 
ATOM 2829 O OH  . TYR C 2 113 ? 314.634 309.974 417.798 1.00 71.64  ? 113 TYR H OH  1 
ATOM 2830 N N   . TRP C 2 114 ? 321.213 315.181 415.269 1.00 70.32  ? 114 TRP H N   1 
ATOM 2831 C CA  . TRP C 2 114 ? 322.350 315.851 414.650 1.00 70.32  ? 114 TRP H CA  1 
ATOM 2832 C C   . TRP C 2 114 ? 323.678 315.145 414.900 1.00 70.32  ? 114 TRP H C   1 
ATOM 2833 O O   . TRP C 2 114 ? 324.313 314.666 413.958 1.00 70.32  ? 114 TRP H O   1 
ATOM 2834 C CB  . TRP C 2 114 ? 322.433 317.294 415.141 1.00 70.32  ? 114 TRP H CB  1 
ATOM 2835 C CG  . TRP C 2 114 ? 321.587 318.220 414.351 1.00 70.32  ? 114 TRP H CG  1 
ATOM 2836 C CD1 . TRP C 2 114 ? 320.230 318.221 414.276 1.00 70.32  ? 114 TRP H CD1 1 
ATOM 2837 C CD2 . TRP C 2 114 ? 322.039 319.277 413.505 1.00 70.32  ? 114 TRP H CD2 1 
ATOM 2838 N NE1 . TRP C 2 114 ? 319.804 319.221 413.440 1.00 70.32  ? 114 TRP H NE1 1 
ATOM 2839 C CE2 . TRP C 2 114 ? 320.898 319.885 412.954 1.00 70.32  ? 114 TRP H CE2 1 
ATOM 2840 C CE3 . TRP C 2 114 ? 323.298 319.774 413.165 1.00 70.32  ? 114 TRP H CE3 1 
ATOM 2841 C CZ2 . TRP C 2 114 ? 320.977 320.961 412.080 1.00 70.32  ? 114 TRP H CZ2 1 
ATOM 2842 C CZ3 . TRP C 2 114 ? 323.374 320.842 412.298 1.00 70.32  ? 114 TRP H CZ3 1 
ATOM 2843 C CH2 . TRP C 2 114 ? 322.222 321.425 411.766 1.00 70.32  ? 114 TRP H CH2 1 
ATOM 2844 N N   . GLY C 2 115 ? 324.112 315.075 416.149 1.00 78.42  ? 115 GLY H N   1 
ATOM 2845 C CA  . GLY C 2 115 ? 325.392 314.486 416.483 1.00 78.42  ? 115 GLY H CA  1 
ATOM 2846 C C   . GLY C 2 115 ? 326.330 315.487 417.135 1.00 78.42  ? 115 GLY H C   1 
ATOM 2847 O O   . GLY C 2 115 ? 326.062 316.685 417.215 1.00 78.42  ? 115 GLY H O   1 
ATOM 2848 N N   . GLN C 2 116 ? 327.458 314.952 417.605 1.00 81.49  ? 116 GLN H N   1 
ATOM 2849 C CA  . GLN C 2 116 ? 328.387 315.749 418.401 1.00 81.49  ? 116 GLN H CA  1 
ATOM 2850 C C   . GLN C 2 116 ? 329.107 316.789 417.551 1.00 81.49  ? 116 GLN H C   1 
ATOM 2851 O O   . GLN C 2 116 ? 329.195 317.961 417.932 1.00 81.49  ? 116 GLN H O   1 
ATOM 2852 C CB  . GLN C 2 116 ? 329.395 314.834 419.101 1.00 81.49  ? 116 GLN H CB  1 
ATOM 2853 C CG  . GLN C 2 116 ? 328.853 313.497 419.628 1.00 81.49  ? 116 GLN H CG  1 
ATOM 2854 C CD  . GLN C 2 116 ? 327.456 313.569 420.240 1.00 81.49  ? 116 GLN H CD  1 
ATOM 2855 O OE1 . GLN C 2 116 ? 327.059 314.581 420.819 1.00 81.49  ? 116 GLN H OE1 1 
ATOM 2856 N NE2 . GLN C 2 116 ? 326.702 312.483 420.108 1.00 81.49  ? 116 GLN H NE2 1 
ATOM 2857 N N   . GLY C 2 117 ? 329.625 316.383 416.405 1.00 82.75  ? 117 GLY H N   1 
ATOM 2858 C CA  . GLY C 2 117 ? 330.380 317.286 415.561 1.00 82.75  ? 117 GLY H CA  1 
ATOM 2859 C C   . GLY C 2 117 ? 331.871 317.215 415.836 1.00 82.75  ? 117 GLY H C   1 
ATOM 2860 O O   . GLY C 2 117 ? 332.316 316.880 416.938 1.00 82.75  ? 117 GLY H O   1 
ATOM 2861 N N   . THR C 2 118 ? 332.661 317.535 414.813 1.00 86.01  ? 118 THR H N   1 
ATOM 2862 C CA  . THR C 2 118 ? 334.114 317.507 414.900 1.00 86.01  ? 118 THR H CA  1 
ATOM 2863 C C   . THR C 2 118 ? 334.681 318.847 414.460 1.00 86.01  ? 118 THR H C   1 
ATOM 2864 O O   . THR C 2 118 ? 334.174 319.466 413.520 1.00 86.01  ? 118 THR H O   1 
ATOM 2865 C CB  . THR C 2 118 ? 334.712 316.399 414.028 1.00 86.01  ? 118 THR H CB  1 
ATOM 2866 O OG1 . THR C 2 118 ? 334.574 316.751 412.647 1.00 86.01  ? 118 THR H OG1 1 
ATOM 2867 C CG2 . THR C 2 118 ? 334.015 315.075 414.285 1.00 86.01  ? 118 THR H CG2 1 
ATOM 2868 N N   . SER C 2 119 ? 335.742 319.284 415.132 1.00 90.36  ? 119 SER H N   1 
ATOM 2869 C CA  . SER C 2 119 ? 336.408 320.542 414.829 1.00 90.36  ? 119 SER H CA  1 
ATOM 2870 C C   . SER C 2 119 ? 337.689 320.262 414.058 1.00 90.36  ? 119 SER H C   1 
ATOM 2871 O O   . SER C 2 119 ? 338.457 319.367 414.425 1.00 90.36  ? 119 SER H O   1 
ATOM 2872 C CB  . SER C 2 119 ? 336.720 321.321 416.107 1.00 90.36  ? 119 SER H CB  1 
ATOM 2873 O OG  . SER C 2 119 ? 337.295 322.580 415.805 1.00 90.36  ? 119 SER H OG  1 
ATOM 2874 N N   . VAL C 2 120 ? 337.914 321.026 412.993 1.00 92.36  ? 120 VAL H N   1 
ATOM 2875 C CA  . VAL C 2 120 ? 339.074 320.862 412.125 1.00 92.36  ? 120 VAL H CA  1 
ATOM 2876 C C   . VAL C 2 120 ? 339.862 322.164 412.120 1.00 92.36  ? 120 VAL H C   1 
ATOM 2877 O O   . VAL C 2 120 ? 339.298 323.239 411.880 1.00 92.36  ? 120 VAL H O   1 
ATOM 2878 C CB  . VAL C 2 120 ? 338.655 320.463 410.700 1.00 92.36  ? 120 VAL H CB  1 
ATOM 2879 C CG1 . VAL C 2 120 ? 339.784 320.724 409.719 1.00 92.36  ? 120 VAL H CG1 1 
ATOM 2880 C CG2 . VAL C 2 120 ? 338.243 319.005 410.666 1.00 92.36  ? 120 VAL H CG2 1 
ATOM 2881 N N   . SER C 2 121 ? 341.162 322.068 412.383 1.00 98.01  ? 121 SER H N   1 
ATOM 2882 C CA  . SER C 2 121 ? 342.032 323.238 412.406 1.00 98.01  ? 121 SER H CA  1 
ATOM 2883 C C   . SER C 2 121 ? 342.370 323.706 410.996 1.00 98.01  ? 121 SER H C   1 
ATOM 2884 O O   . SER C 2 121 ? 343.534 323.713 410.596 1.00 98.01  ? 121 SER H O   1 
ATOM 2885 C CB  . SER C 2 121 ? 343.317 322.932 413.173 1.00 98.01  ? 121 SER H CB  1 
ATOM 2886 O OG  . SER C 2 121 ? 344.254 322.271 412.341 1.00 98.01  ? 121 SER H OG  1 
ATOM 2887 N N   . ILE D 3 5   ? 315.882 330.692 396.927 1.00 67.37  ? 5   ILE L N   1 
ATOM 2888 C CA  . ILE D 3 5   ? 315.143 331.245 398.053 1.00 67.37  ? 5   ILE L CA  1 
ATOM 2889 C C   . ILE D 3 5   ? 316.081 331.526 399.216 1.00 67.37  ? 5   ILE L C   1 
ATOM 2890 O O   . ILE D 3 5   ? 316.823 330.648 399.650 1.00 67.37  ? 5   ILE L O   1 
ATOM 2891 C CB  . ILE D 3 5   ? 314.009 330.307 398.482 1.00 67.37  ? 5   ILE L CB  1 
ATOM 2892 C CG1 . ILE D 3 5   ? 312.980 330.177 397.361 1.00 67.37  ? 5   ILE L CG1 1 
ATOM 2893 C CG2 . ILE D 3 5   ? 313.357 330.804 399.756 1.00 67.37  ? 5   ILE L CG2 1 
ATOM 2894 C CD1 . ILE D 3 5   ? 311.973 329.086 397.591 1.00 67.37  ? 5   ILE L CD1 1 
ATOM 2895 N N   . GLN D 3 6   ? 316.043 332.758 399.718 1.00 72.62  ? 6   GLN L N   1 
ATOM 2896 C CA  . GLN D 3 6   ? 316.925 333.207 400.787 1.00 72.62  ? 6   GLN L CA  1 
ATOM 2897 C C   . GLN D 3 6   ? 316.093 333.508 402.023 1.00 72.62  ? 6   GLN L C   1 
ATOM 2898 O O   . GLN D 3 6   ? 315.149 334.302 401.961 1.00 72.62  ? 6   GLN L O   1 
ATOM 2899 C CB  . GLN D 3 6   ? 317.713 334.446 400.359 1.00 72.62  ? 6   GLN L CB  1 
ATOM 2900 C CG  . GLN D 3 6   ? 318.291 334.379 398.951 1.00 72.62  ? 6   GLN L CG  1 
ATOM 2901 C CD  . GLN D 3 6   ? 319.302 333.261 398.765 1.00 72.62  ? 6   GLN L CD  1 
ATOM 2902 O OE1 . GLN D 3 6   ? 319.738 332.628 399.726 1.00 72.62  ? 6   GLN L OE1 1 
ATOM 2903 N NE2 . GLN D 3 6   ? 319.680 333.014 397.517 1.00 72.62  ? 6   GLN L NE2 1 
ATOM 2904 N N   . MET D 3 7   ? 316.447 332.884 403.142 1.00 72.79  ? 7   MET L N   1 
ATOM 2905 C CA  . MET D 3 7   ? 315.771 333.125 404.407 1.00 72.79  ? 7   MET L CA  1 
ATOM 2906 C C   . MET D 3 7   ? 316.554 334.140 405.226 1.00 72.79  ? 7   MET L C   1 
ATOM 2907 O O   . MET D 3 7   ? 317.787 334.156 405.200 1.00 72.79  ? 7   MET L O   1 
ATOM 2908 C CB  . MET D 3 7   ? 315.619 331.827 405.200 1.00 72.79  ? 7   MET L CB  1 
ATOM 2909 C CG  . MET D 3 7   ? 315.369 330.602 404.346 1.00 72.79  ? 7   MET L CG  1 
ATOM 2910 S SD  . MET D 3 7   ? 313.675 330.510 403.753 1.00 72.79  ? 7   MET L SD  1 
ATOM 2911 C CE  . MET D 3 7   ? 312.784 330.667 405.293 1.00 72.79  ? 7   MET L CE  1 
ATOM 2912 N N   . THR D 3 8   ? 315.831 334.987 405.952 1.00 76.83  ? 8   THR L N   1 
ATOM 2913 C CA  . THR D 3 8   ? 316.458 335.966 406.825 1.00 76.83  ? 8   THR L CA  1 
ATOM 2914 C C   . THR D 3 8   ? 315.637 336.114 408.096 1.00 76.83  ? 8   THR L C   1 
ATOM 2915 O O   . THR D 3 8   ? 314.420 335.922 408.095 1.00 76.83  ? 8   THR L O   1 
ATOM 2916 C CB  . THR D 3 8   ? 316.614 337.327 406.134 1.00 76.83  ? 8   THR L CB  1 
ATOM 2917 O OG1 . THR D 3 8   ? 317.296 338.233 407.009 1.00 76.83  ? 8   THR L OG1 1 
ATOM 2918 C CG2 . THR D 3 8   ? 315.259 337.905 405.769 1.00 76.83  ? 8   THR L CG2 1 
ATOM 2919 N N   . GLN D 3 9   ? 316.322 336.452 409.183 1.00 78.76  ? 9   GLN L N   1 
ATOM 2920 C CA  . GLN D 3 9   ? 315.697 336.691 410.475 1.00 78.76  ? 9   GLN L CA  1 
ATOM 2921 C C   . GLN D 3 9   ? 315.858 338.161 410.831 1.00 78.76  ? 9   GLN L C   1 
ATOM 2922 O O   . GLN D 3 9   ? 316.967 338.701 410.758 1.00 78.76  ? 9   GLN L O   1 
ATOM 2923 C CB  . GLN D 3 9   ? 316.319 335.807 411.556 1.00 78.76  ? 9   GLN L CB  1 
ATOM 2924 C CG  . GLN D 3 9   ? 316.637 334.399 411.092 1.00 78.76  ? 9   GLN L CG  1 
ATOM 2925 C CD  . GLN D 3 9   ? 316.674 333.407 412.233 1.00 78.76  ? 9   GLN L CD  1 
ATOM 2926 O OE1 . GLN D 3 9   ? 316.229 333.703 413.341 1.00 78.76  ? 9   GLN L OE1 1 
ATOM 2927 N NE2 . GLN D 3 9   ? 317.204 332.221 411.970 1.00 78.76  ? 9   GLN L NE2 1 
ATOM 2928 N N   . SER D 3 10  ? 314.760 338.802 411.212 1.00 85.84  ? 10  SER L N   1 
ATOM 2929 C CA  . SER D 3 10  ? 314.772 340.247 411.410 1.00 85.84  ? 10  SER L CA  1 
ATOM 2930 C C   . SER D 3 10  ? 315.475 340.693 412.695 1.00 85.84  ? 10  SER L C   1 
ATOM 2931 O O   . SER D 3 10  ? 316.316 341.599 412.627 1.00 85.84  ? 10  SER L O   1 
ATOM 2932 C CB  . SER D 3 10  ? 313.344 340.804 411.361 1.00 85.84  ? 10  SER L CB  1 
ATOM 2933 O OG  . SER D 3 10  ? 312.563 340.404 412.471 1.00 85.84  ? 10  SER L OG  1 
ATOM 2934 N N   . PRO D 3 11  ? 315.179 340.116 413.886 1.00 85.58  ? 11  PRO L N   1 
ATOM 2935 C CA  . PRO D 3 11  ? 315.726 340.713 415.114 1.00 85.58  ? 11  PRO L CA  1 
ATOM 2936 C C   . PRO D 3 11  ? 317.241 340.609 415.219 1.00 85.58  ? 11  PRO L C   1 
ATOM 2937 O O   . PRO D 3 11  ? 317.919 341.620 415.435 1.00 85.58  ? 11  PRO L O   1 
ATOM 2938 C CB  . PRO D 3 11  ? 315.029 339.926 416.229 1.00 85.58  ? 11  PRO L CB  1 
ATOM 2939 C CG  . PRO D 3 11  ? 314.726 338.620 415.632 1.00 85.58  ? 11  PRO L CG  1 
ATOM 2940 C CD  . PRO D 3 11  ? 314.480 338.847 414.171 1.00 85.58  ? 11  PRO L CD  1 
ATOM 2941 N N   . ALA D 3 12  ? 317.776 339.395 415.090 1.00 86.05  ? 12  ALA L N   1 
ATOM 2942 C CA  . ALA D 3 12  ? 319.197 339.057 415.155 1.00 86.05  ? 12  ALA L CA  1 
ATOM 2943 C C   . ALA D 3 12  ? 319.795 339.263 416.540 1.00 86.05  ? 12  ALA L C   1 
ATOM 2944 O O   . ALA D 3 12  ? 320.955 338.891 416.759 1.00 86.05  ? 12  ALA L O   1 
ATOM 2945 C CB  . ALA D 3 12  ? 320.035 339.837 414.130 1.00 86.05  ? 12  ALA L CB  1 
ATOM 2946 N N   . SER D 3 13  ? 319.044 339.826 417.487 1.00 91.43  ? 13  SER L N   1 
ATOM 2947 C CA  . SER D 3 13  ? 319.492 340.009 418.862 1.00 91.43  ? 13  SER L CA  1 
ATOM 2948 C C   . SER D 3 13  ? 318.303 340.391 419.733 1.00 91.43  ? 13  SER L C   1 
ATOM 2949 O O   . SER D 3 13  ? 317.547 341.305 419.389 1.00 91.43  ? 13  SER L O   1 
ATOM 2950 C CB  . SER D 3 13  ? 320.582 341.079 418.944 1.00 91.43  ? 13  SER L CB  1 
ATOM 2951 O OG  . SER D 3 13  ? 320.145 342.295 418.364 1.00 91.43  ? 13  SER L OG  1 
ATOM 2952 N N   . LEU D 3 14  ? 318.125 339.706 420.860 1.00 94.94  ? 14  LEU L N   1 
ATOM 2953 C CA  . LEU D 3 14  ? 316.977 339.945 421.722 1.00 94.94  ? 14  LEU L CA  1 
ATOM 2954 C C   . LEU D 3 14  ? 317.411 339.845 423.176 1.00 94.94  ? 14  LEU L C   1 
ATOM 2955 O O   . LEU D 3 14  ? 318.184 338.956 423.539 1.00 94.94  ? 14  LEU L O   1 
ATOM 2956 C CB  . LEU D 3 14  ? 315.854 338.948 421.422 1.00 94.94  ? 14  LEU L CB  1 
ATOM 2957 C CG  . LEU D 3 14  ? 314.424 339.422 421.672 1.00 94.94  ? 14  LEU L CG  1 
ATOM 2958 C CD1 . LEU D 3 14  ? 313.995 340.398 420.590 1.00 94.94  ? 14  LEU L CD1 1 
ATOM 2959 C CD2 . LEU D 3 14  ? 313.484 338.234 421.719 1.00 94.94  ? 14  LEU L CD2 1 
ATOM 2960 N N   . SER D 3 15  ? 316.906 340.761 424.005 1.00 99.92  ? 15  SER L N   1 
ATOM 2961 C CA  . SER D 3 15  ? 317.366 340.883 425.381 1.00 99.92  ? 15  SER L CA  1 
ATOM 2962 C C   . SER D 3 15  ? 316.317 340.548 426.431 1.00 99.92  ? 15  SER L C   1 
ATOM 2963 O O   . SER D 3 15  ? 316.632 340.606 427.624 1.00 99.92  ? 15  SER L O   1 
ATOM 2964 C CB  . SER D 3 15  ? 317.880 342.306 425.644 1.00 99.92  ? 15  SER L CB  1 
ATOM 2965 O OG  . SER D 3 15  ? 316.809 343.232 425.681 1.00 99.92  ? 15  SER L OG  1 
ATOM 2966 N N   . ALA D 3 16  ? 315.092 340.214 426.031 1.00 101.78 ? 16  ALA L N   1 
ATOM 2967 C CA  . ALA D 3 16  ? 314.039 339.914 426.995 1.00 101.78 ? 16  ALA L CA  1 
ATOM 2968 C C   . ALA D 3 16  ? 314.453 338.752 427.889 1.00 101.78 ? 16  ALA L C   1 
ATOM 2969 O O   . ALA D 3 16  ? 314.721 337.649 427.405 1.00 101.78 ? 16  ALA L O   1 
ATOM 2970 C CB  . ALA D 3 16  ? 312.738 339.595 426.265 1.00 101.78 ? 16  ALA L CB  1 
ATOM 2971 N N   . SER D 3 17  ? 314.508 339.002 429.198 1.00 103.82 ? 17  SER L N   1 
ATOM 2972 C CA  . SER D 3 17  ? 315.139 338.046 430.108 1.00 103.82 ? 17  SER L CA  1 
ATOM 2973 C C   . SER D 3 17  ? 314.193 336.925 430.535 1.00 103.82 ? 17  SER L C   1 
ATOM 2974 O O   . SER D 3 17  ? 314.399 335.760 430.185 1.00 103.82 ? 17  SER L O   1 
ATOM 2975 C CB  . SER D 3 17  ? 315.681 338.786 431.334 1.00 103.82 ? 17  SER L CB  1 
ATOM 2976 O OG  . SER D 3 17  ? 314.628 339.405 432.053 1.00 103.82 ? 17  SER L OG  1 
ATOM 2977 N N   . VAL D 3 18  ? 313.143 337.262 431.281 1.00 103.79 ? 18  VAL L N   1 
ATOM 2978 C CA  . VAL D 3 18  ? 312.328 336.254 431.957 1.00 103.79 ? 18  VAL L CA  1 
ATOM 2979 C C   . VAL D 3 18  ? 310.883 336.731 431.991 1.00 103.79 ? 18  VAL L C   1 
ATOM 2980 O O   . VAL D 3 18  ? 310.612 337.915 432.211 1.00 103.79 ? 18  VAL L O   1 
ATOM 2981 C CB  . VAL D 3 18  ? 312.847 335.969 433.387 1.00 103.79 ? 18  VAL L CB  1 
ATOM 2982 C CG1 . VAL D 3 18  ? 311.849 335.133 434.171 1.00 103.79 ? 18  VAL L CG1 1 
ATOM 2983 C CG2 . VAL D 3 18  ? 314.195 335.262 433.353 1.00 103.79 ? 18  VAL L CG2 1 
ATOM 2984 N N   . GLY D 3 19  ? 309.955 335.800 431.775 1.00 104.13 ? 19  GLY L N   1 
ATOM 2985 C CA  . GLY D 3 19  ? 308.544 336.077 431.957 1.00 104.13 ? 19  GLY L CA  1 
ATOM 2986 C C   . GLY D 3 19  ? 307.843 336.591 430.718 1.00 104.13 ? 19  GLY L C   1 
ATOM 2987 O O   . GLY D 3 19  ? 306.855 336.004 430.268 1.00 104.13 ? 19  GLY L O   1 
ATOM 2988 N N   . GLU D 3 20  ? 308.344 337.689 430.161 1.00 104.21 ? 20  GLU L N   1 
ATOM 2989 C CA  . GLU D 3 20  ? 307.704 338.306 429.010 1.00 104.21 ? 20  GLU L CA  1 
ATOM 2990 C C   . GLU D 3 20  ? 307.793 337.406 427.783 1.00 104.21 ? 20  GLU L C   1 
ATOM 2991 O O   . GLU D 3 20  ? 308.760 336.664 427.593 1.00 104.21 ? 20  GLU L O   1 
ATOM 2992 C CB  . GLU D 3 20  ? 308.339 339.662 428.708 1.00 104.21 ? 20  GLU L CB  1 
ATOM 2993 C CG  . GLU D 3 20  ? 309.823 339.596 428.399 1.00 104.21 ? 20  GLU L CG  1 
ATOM 2994 C CD  . GLU D 3 20  ? 310.678 339.998 429.581 1.00 104.21 ? 20  GLU L CD  1 
ATOM 2995 O OE1 . GLU D 3 20  ? 310.119 340.192 430.679 1.00 104.21 ? 20  GLU L OE1 1 
ATOM 2996 O OE2 . GLU D 3 20  ? 311.909 340.120 429.414 1.00 104.21 ? 20  GLU L OE2 1 
ATOM 2997 N N   . THR D 3 21  ? 306.758 337.473 426.952 1.00 99.54  ? 21  THR L N   1 
ATOM 2998 C CA  . THR D 3 21  ? 306.743 336.726 425.705 1.00 99.54  ? 21  THR L CA  1 
ATOM 2999 C C   . THR D 3 21  ? 307.704 337.348 424.700 1.00 99.54  ? 21  THR L C   1 
ATOM 3000 O O   . THR D 3 21  ? 307.935 338.559 424.692 1.00 99.54  ? 21  THR L O   1 
ATOM 3001 C CB  . THR D 3 21  ? 305.333 336.687 425.117 1.00 99.54  ? 21  THR L CB  1 
ATOM 3002 O OG1 . THR D 3 21  ? 304.897 338.021 424.830 1.00 99.54  ? 21  THR L OG1 1 
ATOM 3003 C CG2 . THR D 3 21  ? 304.365 336.045 426.099 1.00 99.54  ? 21  THR L CG2 1 
ATOM 3004 N N   . VAL D 3 22  ? 308.270 336.500 423.843 1.00 94.19  ? 22  VAL L N   1 
ATOM 3005 C CA  . VAL D 3 22  ? 309.193 336.936 422.806 1.00 94.19  ? 22  VAL L CA  1 
ATOM 3006 C C   . VAL D 3 22  ? 308.733 336.373 421.470 1.00 94.19  ? 22  VAL L C   1 
ATOM 3007 O O   . VAL D 3 22  ? 308.018 335.372 421.401 1.00 94.19  ? 22  VAL L O   1 
ATOM 3008 C CB  . VAL D 3 22  ? 310.646 336.506 423.095 1.00 94.19  ? 22  VAL L CB  1 
ATOM 3009 C CG1 . VAL D 3 22  ? 311.064 336.956 424.478 1.00 94.19  ? 22  VAL L CG1 1 
ATOM 3010 C CG2 . VAL D 3 22  ? 310.791 335.003 422.959 1.00 94.19  ? 22  VAL L CG2 1 
ATOM 3011 N N   . THR D 3 23  ? 309.150 337.042 420.399 1.00 87.17  ? 23  THR L N   1 
ATOM 3012 C CA  . THR D 3 23  ? 308.830 336.603 419.051 1.00 87.17  ? 23  THR L CA  1 
ATOM 3013 C C   . THR D 3 23  ? 310.059 336.733 418.165 1.00 87.17  ? 23  THR L C   1 
ATOM 3014 O O   . THR D 3 23  ? 310.879 337.636 418.350 1.00 87.17  ? 23  THR L O   1 
ATOM 3015 C CB  . THR D 3 23  ? 307.659 337.401 418.459 1.00 87.17  ? 23  THR L CB  1 
ATOM 3016 O OG1 . THR D 3 23  ? 307.275 336.830 417.203 1.00 87.17  ? 23  THR L OG1 1 
ATOM 3017 C CG2 . THR D 3 23  ? 308.040 338.860 418.257 1.00 87.17  ? 23  THR L CG2 1 
ATOM 3018 N N   . ILE D 3 24  ? 310.192 335.807 417.221 1.00 81.39  ? 24  ILE L N   1 
ATOM 3019 C CA  . ILE D 3 24  ? 311.249 335.834 416.218 1.00 81.39  ? 24  ILE L CA  1 
ATOM 3020 C C   . ILE D 3 24  ? 310.597 335.659 414.857 1.00 81.39  ? 24  ILE L C   1 
ATOM 3021 O O   . ILE D 3 24  ? 309.890 334.673 414.628 1.00 81.39  ? 24  ILE L O   1 
ATOM 3022 C CB  . ILE D 3 24  ? 312.298 334.734 416.457 1.00 81.39  ? 24  ILE L CB  1 
ATOM 3023 C CG1 . ILE D 3 24  ? 313.005 334.950 417.793 1.00 81.39  ? 24  ILE L CG1 1 
ATOM 3024 C CG2 . ILE D 3 24  ? 313.304 334.710 415.323 1.00 81.39  ? 24  ILE L CG2 1 
ATOM 3025 C CD1 . ILE D 3 24  ? 313.859 333.782 418.221 1.00 81.39  ? 24  ILE L CD1 1 
ATOM 3026 N N   . THR D 3 25  ? 310.835 336.604 413.957 1.00 81.43  ? 25  THR L N   1 
ATOM 3027 C CA  . THR D 3 25  ? 310.217 336.590 412.642 1.00 81.43  ? 25  THR L CA  1 
ATOM 3028 C C   . THR D 3 25  ? 311.196 336.060 411.603 1.00 81.43  ? 25  THR L C   1 
ATOM 3029 O O   . THR D 3 25  ? 312.396 335.922 411.850 1.00 81.43  ? 25  THR L O   1 
ATOM 3030 C CB  . THR D 3 25  ? 309.734 337.990 412.250 1.00 81.43  ? 25  THR L CB  1 
ATOM 3031 O OG1 . THR D 3 25  ? 310.863 338.853 412.069 1.00 81.43  ? 25  THR L OG1 1 
ATOM 3032 C CG2 . THR D 3 25  ? 308.836 338.561 413.333 1.00 81.43  ? 25  THR L CG2 1 
ATOM 3033 N N   . CYS D 3 26  ? 310.657 335.756 410.426 1.00 76.75  ? 26  CYS L N   1 
ATOM 3034 C CA  . CYS D 3 26  ? 311.459 335.255 409.323 1.00 76.75  ? 26  CYS L CA  1 
ATOM 3035 C C   . CYS D 3 26  ? 310.837 335.700 408.009 1.00 76.75  ? 26  CYS L C   1 
ATOM 3036 O O   . CYS D 3 26  ? 309.628 335.928 407.923 1.00 76.75  ? 26  CYS L O   1 
ATOM 3037 C CB  . CYS D 3 26  ? 311.576 333.730 409.359 1.00 76.75  ? 26  CYS L CB  1 
ATOM 3038 S SG  . CYS D 3 26  ? 312.434 333.043 407.936 1.00 76.75  ? 26  CYS L SG  1 
ATOM 3039 N N   . ARG D 3 27  ? 311.677 335.819 406.987 1.00 74.78  ? 27  ARG L N   1 
ATOM 3040 C CA  . ARG D 3 27  ? 311.236 336.206 405.656 1.00 74.78  ? 27  ARG L CA  1 
ATOM 3041 C C   . ARG D 3 27  ? 311.924 335.330 404.625 1.00 74.78  ? 27  ARG L C   1 
ATOM 3042 O O   . ARG D 3 27  ? 313.088 334.959 404.793 1.00 74.78  ? 27  ARG L O   1 
ATOM 3043 C CB  . ARG D 3 27  ? 311.538 337.680 405.370 1.00 74.78  ? 27  ARG L CB  1 
ATOM 3044 C CG  . ARG D 3 27  ? 310.747 338.257 404.213 1.00 74.78  ? 27  ARG L CG  1 
ATOM 3045 C CD  . ARG D 3 27  ? 309.432 338.835 404.690 1.00 74.78  ? 27  ARG L CD  1 
ATOM 3046 N NE  . ARG D 3 27  ? 309.587 339.563 405.943 1.00 74.78  ? 27  ARG L NE  1 
ATOM 3047 C CZ  . ARG D 3 27  ? 309.978 340.827 406.030 1.00 74.78  ? 27  ARG L CZ  1 
ATOM 3048 N NH1 . ARG D 3 27  ? 310.250 341.541 404.951 1.00 74.78  ? 27  ARG L NH1 1 
ATOM 3049 N NH2 . ARG D 3 27  ? 310.096 341.389 407.230 1.00 74.78  ? 27  ARG L NH2 1 
ATOM 3050 N N   . ALA D 3 28  ? 311.200 335.007 403.559 1.00 69.71  ? 28  ALA L N   1 
ATOM 3051 C CA  . ALA D 3 28  ? 311.727 334.227 402.451 1.00 69.71  ? 28  ALA L CA  1 
ATOM 3052 C C   . ALA D 3 28  ? 311.558 335.012 401.160 1.00 69.71  ? 28  ALA L C   1 
ATOM 3053 O O   . ALA D 3 28  ? 310.527 335.654 400.944 1.00 69.71  ? 28  ALA L O   1 
ATOM 3054 C CB  . ALA D 3 28  ? 311.026 332.873 402.340 1.00 69.71  ? 28  ALA L CB  1 
ATOM 3055 N N   . SER D 3 29  ? 312.582 334.964 400.305 1.00 68.28  ? 29  SER L N   1 
ATOM 3056 C CA  . SER D 3 29  ? 312.524 335.707 399.051 1.00 68.28  ? 29  SER L CA  1 
ATOM 3057 C C   . SER D 3 29  ? 311.454 335.156 398.121 1.00 68.28  ? 29  SER L C   1 
ATOM 3058 O O   . SER D 3 29  ? 310.951 335.883 397.257 1.00 68.28  ? 29  SER L O   1 
ATOM 3059 C CB  . SER D 3 29  ? 313.885 335.683 398.360 1.00 68.28  ? 29  SER L CB  1 
ATOM 3060 O OG  . SER D 3 29  ? 314.204 334.378 397.915 1.00 68.28  ? 29  SER L OG  1 
ATOM 3061 N N   . GLY D 3 30  ? 311.096 333.879 398.277 1.00 66.80  ? 30  GLY L N   1 
ATOM 3062 C CA  . GLY D 3 30  ? 310.058 333.263 397.486 1.00 66.80  ? 30  GLY L CA  1 
ATOM 3063 C C   . GLY D 3 30  ? 308.963 332.696 398.378 1.00 66.80  ? 30  GLY L C   1 
ATOM 3064 O O   . GLY D 3 30  ? 309.015 332.786 399.609 1.00 66.80  ? 30  GLY L O   1 
ATOM 3065 N N   . ASN D 3 31  ? 307.963 332.105 397.733 1.00 63.91  ? 31  ASN L N   1 
ATOM 3066 C CA  . ASN D 3 31  ? 306.848 331.504 398.449 1.00 63.91  ? 31  ASN L CA  1 
ATOM 3067 C C   . ASN D 3 31  ? 307.175 330.055 398.782 1.00 63.91  ? 31  ASN L C   1 
ATOM 3068 O O   . ASN D 3 31  ? 307.362 329.232 397.880 1.00 63.91  ? 31  ASN L O   1 
ATOM 3069 C CB  . ASN D 3 31  ? 305.573 331.590 397.615 1.00 63.91  ? 31  ASN L CB  1 
ATOM 3070 C CG  . ASN D 3 31  ? 304.332 331.268 398.418 1.00 63.91  ? 31  ASN L CG  1 
ATOM 3071 O OD1 . ASN D 3 31  ? 304.166 331.744 399.538 1.00 63.91  ? 31  ASN L OD1 1 
ATOM 3072 N ND2 . ASN D 3 31  ? 303.449 330.461 397.847 1.00 63.91  ? 31  ASN L ND2 1 
ATOM 3073 N N   . ILE D 3 32  ? 307.250 329.745 400.072 1.00 60.20  ? 32  ILE L N   1 
ATOM 3074 C CA  . ILE D 3 32  ? 307.426 328.381 400.552 1.00 60.20  ? 32  ILE L CA  1 
ATOM 3075 C C   . ILE D 3 32  ? 306.147 327.990 401.276 1.00 60.20  ? 32  ILE L C   1 
ATOM 3076 O O   . ILE D 3 32  ? 305.684 328.711 402.168 1.00 60.20  ? 32  ILE L O   1 
ATOM 3077 C CB  . ILE D 3 32  ? 308.659 328.242 401.460 1.00 60.20  ? 32  ILE L CB  1 
ATOM 3078 C CG1 . ILE D 3 32  ? 308.624 329.255 402.603 1.00 60.20  ? 32  ILE L CG1 1 
ATOM 3079 C CG2 . ILE D 3 32  ? 309.921 328.457 400.661 1.00 60.20  ? 32  ILE L CG2 1 
ATOM 3080 C CD1 . ILE D 3 32  ? 309.660 328.998 403.666 1.00 60.20  ? 32  ILE L CD1 1 
ATOM 3081 N N   . HIS D 3 33  ? 305.561 326.864 400.878 1.00 57.82  ? 33  HIS L N   1 
ATOM 3082 C CA  . HIS D 3 33  ? 304.244 326.469 401.370 1.00 57.82  ? 33  HIS L CA  1 
ATOM 3083 C C   . HIS D 3 33  ? 304.392 325.709 402.689 1.00 57.82  ? 33  HIS L C   1 
ATOM 3084 O O   . HIS D 3 33  ? 304.228 324.491 402.775 1.00 57.82  ? 33  HIS L O   1 
ATOM 3085 C CB  . HIS D 3 33  ? 303.515 325.653 400.314 1.00 57.82  ? 33  HIS L CB  1 
ATOM 3086 C CG  . HIS D 3 33  ? 303.274 326.402 399.041 1.00 57.82  ? 33  HIS L CG  1 
ATOM 3087 N ND1 . HIS D 3 33  ? 304.176 326.406 398.000 1.00 57.82  ? 33  HIS L ND1 1 
ATOM 3088 C CD2 . HIS D 3 33  ? 302.237 327.173 398.641 1.00 57.82  ? 33  HIS L CD2 1 
ATOM 3089 C CE1 . HIS D 3 33  ? 303.704 327.147 397.013 1.00 57.82  ? 33  HIS L CE1 1 
ATOM 3090 N NE2 . HIS D 3 33  ? 302.527 327.624 397.377 1.00 57.82  ? 33  HIS L NE2 1 
ATOM 3091 N N   . TYR D 3 34  ? 304.712 326.472 403.733 1.00 62.26  ? 34  TYR L N   1 
ATOM 3092 C CA  . TYR D 3 34  ? 304.847 326.015 405.114 1.00 62.26  ? 34  TYR L CA  1 
ATOM 3093 C C   . TYR D 3 34  ? 305.993 325.037 405.325 1.00 62.26  ? 34  TYR L C   1 
ATOM 3094 O O   . TYR D 3 34  ? 306.043 324.382 406.370 1.00 62.26  ? 34  TYR L O   1 
ATOM 3095 C CB  . TYR D 3 34  ? 303.560 325.371 405.641 1.00 62.26  ? 34  TYR L CB  1 
ATOM 3096 C CG  . TYR D 3 34  ? 302.331 326.245 405.566 1.00 62.26  ? 34  TYR L CG  1 
ATOM 3097 C CD1 . TYR D 3 34  ? 301.629 326.389 404.381 1.00 62.26  ? 34  TYR L CD1 1 
ATOM 3098 C CD2 . TYR D 3 34  ? 301.866 326.912 406.686 1.00 62.26  ? 34  TYR L CD2 1 
ATOM 3099 C CE1 . TYR D 3 34  ? 300.506 327.179 404.309 1.00 62.26  ? 34  TYR L CE1 1 
ATOM 3100 C CE2 . TYR D 3 34  ? 300.741 327.706 406.624 1.00 62.26  ? 34  TYR L CE2 1 
ATOM 3101 C CZ  . TYR D 3 34  ? 300.065 327.835 405.432 1.00 62.26  ? 34  TYR L CZ  1 
ATOM 3102 O OH  . TYR D 3 34  ? 298.942 328.623 405.361 1.00 62.26  ? 34  TYR L OH  1 
ATOM 3103 N N   . PHE D 3 35  ? 306.919 324.912 404.375 1.00 53.43  ? 35  PHE L N   1 
ATOM 3104 C CA  . PHE D 3 35  ? 308.046 323.990 404.522 1.00 53.43  ? 35  PHE L CA  1 
ATOM 3105 C C   . PHE D 3 35  ? 309.178 324.711 405.246 1.00 53.43  ? 35  PHE L C   1 
ATOM 3106 O O   . PHE D 3 35  ? 310.155 325.164 404.649 1.00 53.43  ? 35  PHE L O   1 
ATOM 3107 C CB  . PHE D 3 35  ? 308.493 323.466 403.165 1.00 53.43  ? 35  PHE L CB  1 
ATOM 3108 C CG  . PHE D 3 35  ? 307.554 322.466 402.560 1.00 53.43  ? 35  PHE L CG  1 
ATOM 3109 C CD1 . PHE D 3 35  ? 307.536 321.159 403.003 1.00 53.43  ? 35  PHE L CD1 1 
ATOM 3110 C CD2 . PHE D 3 35  ? 306.703 322.828 401.537 1.00 53.43  ? 35  PHE L CD2 1 
ATOM 3111 C CE1 . PHE D 3 35  ? 306.680 320.240 402.446 1.00 53.43  ? 35  PHE L CE1 1 
ATOM 3112 C CE2 . PHE D 3 35  ? 305.846 321.910 400.977 1.00 53.43  ? 35  PHE L CE2 1 
ATOM 3113 C CZ  . PHE D 3 35  ? 305.836 320.616 401.430 1.00 53.43  ? 35  PHE L CZ  1 
ATOM 3114 N N   . LEU D 3 36  ? 309.041 324.810 406.565 1.00 60.50  ? 36  LEU L N   1 
ATOM 3115 C CA  . LEU D 3 36  ? 310.005 325.534 407.381 1.00 60.50  ? 36  LEU L CA  1 
ATOM 3116 C C   . LEU D 3 36  ? 310.165 324.836 408.722 1.00 60.50  ? 36  LEU L C   1 
ATOM 3117 O O   . LEU D 3 36  ? 309.200 324.296 409.267 1.00 60.50  ? 36  LEU L O   1 
ATOM 3118 C CB  . LEU D 3 36  ? 309.563 326.992 407.575 1.00 60.50  ? 36  LEU L CB  1 
ATOM 3119 C CG  . LEU D 3 36  ? 310.522 327.991 408.217 1.00 60.50  ? 36  LEU L CG  1 
ATOM 3120 C CD1 . LEU D 3 36  ? 310.241 329.378 407.692 1.00 60.50  ? 36  LEU L CD1 1 
ATOM 3121 C CD2 . LEU D 3 36  ? 310.381 327.986 409.720 1.00 60.50  ? 36  LEU L CD2 1 
ATOM 3122 N N   . ALA D 3 37  ? 311.387 324.855 409.252 1.00 62.74  ? 37  ALA L N   1 
ATOM 3123 C CA  . ALA D 3 37  ? 311.703 324.239 410.531 1.00 62.74  ? 37  ALA L CA  1 
ATOM 3124 C C   . ALA D 3 37  ? 312.518 325.202 411.379 1.00 62.74  ? 37  ALA L C   1 
ATOM 3125 O O   . ALA D 3 37  ? 313.261 326.035 410.857 1.00 62.74  ? 37  ALA L O   1 
ATOM 3126 C CB  . ALA D 3 37  ? 312.479 322.933 410.349 1.00 62.74  ? 37  ALA L CB  1 
ATOM 3127 N N   . TRP D 3 38  ? 312.372 325.082 412.696 1.00 68.22  ? 38  TRP L N   1 
ATOM 3128 C CA  . TRP D 3 38  ? 313.090 325.914 413.651 1.00 68.22  ? 38  TRP L CA  1 
ATOM 3129 C C   . TRP D 3 38  ? 314.024 325.048 414.483 1.00 68.22  ? 38  TRP L C   1 
ATOM 3130 O O   . TRP D 3 38  ? 313.635 323.976 414.954 1.00 68.22  ? 38  TRP L O   1 
ATOM 3131 C CB  . TRP D 3 38  ? 312.129 326.673 414.570 1.00 68.22  ? 38  TRP L CB  1 
ATOM 3132 C CG  . TRP D 3 38  ? 311.306 327.705 413.863 1.00 68.22  ? 38  TRP L CG  1 
ATOM 3133 C CD1 . TRP D 3 38  ? 310.052 327.544 413.361 1.00 68.22  ? 38  TRP L CD1 1 
ATOM 3134 C CD2 . TRP D 3 38  ? 311.680 329.057 413.581 1.00 68.22  ? 38  TRP L CD2 1 
ATOM 3135 N NE1 . TRP D 3 38  ? 309.620 328.711 412.785 1.00 68.22  ? 38  TRP L NE1 1 
ATOM 3136 C CE2 . TRP D 3 38  ? 310.603 329.655 412.905 1.00 68.22  ? 38  TRP L CE2 1 
ATOM 3137 C CE3 . TRP D 3 38  ? 312.822 329.820 413.835 1.00 68.22  ? 38  TRP L CE3 1 
ATOM 3138 C CZ2 . TRP D 3 38  ? 310.633 330.978 412.478 1.00 68.22  ? 38  TRP L CZ2 1 
ATOM 3139 C CZ3 . TRP D 3 38  ? 312.849 331.131 413.411 1.00 68.22  ? 38  TRP L CZ3 1 
ATOM 3140 C CH2 . TRP D 3 38  ? 311.763 331.697 412.740 1.00 68.22  ? 38  TRP L CH2 1 
ATOM 3141 N N   . TYR D 3 39  ? 315.253 325.520 414.663 1.00 69.13  ? 39  TYR L N   1 
ATOM 3142 C CA  . TYR D 3 39  ? 316.281 324.796 415.394 1.00 69.13  ? 39  TYR L CA  1 
ATOM 3143 C C   . TYR D 3 39  ? 316.770 325.636 416.564 1.00 69.13  ? 39  TYR L C   1 
ATOM 3144 O O   . TYR D 3 39  ? 316.895 326.859 416.451 1.00 69.13  ? 39  TYR L O   1 
ATOM 3145 C CB  . TYR D 3 39  ? 317.460 324.443 414.488 1.00 69.13  ? 39  TYR L CB  1 
ATOM 3146 C CG  . TYR D 3 39  ? 317.136 323.426 413.423 1.00 69.13  ? 39  TYR L CG  1 
ATOM 3147 C CD1 . TYR D 3 39  ? 317.078 322.076 413.723 1.00 69.13  ? 39  TYR L CD1 1 
ATOM 3148 C CD2 . TYR D 3 39  ? 316.895 323.815 412.118 1.00 69.13  ? 39  TYR L CD2 1 
ATOM 3149 C CE1 . TYR D 3 39  ? 316.788 321.146 412.755 1.00 69.13  ? 39  TYR L CE1 1 
ATOM 3150 C CE2 . TYR D 3 39  ? 316.603 322.893 411.146 1.00 69.13  ? 39  TYR L CE2 1 
ATOM 3151 C CZ  . TYR D 3 39  ? 316.550 321.559 411.469 1.00 69.13  ? 39  TYR L CZ  1 
ATOM 3152 O OH  . TYR D 3 39  ? 316.258 320.633 410.500 1.00 69.13  ? 39  TYR L OH  1 
ATOM 3153 N N   . GLN D 3 40  ? 317.041 324.976 417.685 1.00 77.85  ? 40  GLN L N   1 
ATOM 3154 C CA  . GLN D 3 40  ? 317.541 325.626 418.888 1.00 77.85  ? 40  GLN L CA  1 
ATOM 3155 C C   . GLN D 3 40  ? 318.904 325.054 419.243 1.00 77.85  ? 40  GLN L C   1 
ATOM 3156 O O   . GLN D 3 40  ? 319.070 323.832 419.300 1.00 77.85  ? 40  GLN L O   1 
ATOM 3157 C CB  . GLN D 3 40  ? 316.574 325.436 420.056 1.00 77.85  ? 40  GLN L CB  1 
ATOM 3158 C CG  . GLN D 3 40  ? 317.147 325.841 421.398 1.00 77.85  ? 40  GLN L CG  1 
ATOM 3159 C CD  . GLN D 3 40  ? 316.144 325.709 422.520 1.00 77.85  ? 40  GLN L CD  1 
ATOM 3160 O OE1 . GLN D 3 40  ? 315.586 326.699 422.989 1.00 77.85  ? 40  GLN L OE1 1 
ATOM 3161 N NE2 . GLN D 3 40  ? 315.908 324.479 422.960 1.00 77.85  ? 40  GLN L NE2 1 
ATOM 3162 N N   . GLN D 3 41  ? 319.871 325.934 419.491 1.00 83.68  ? 41  GLN L N   1 
ATOM 3163 C CA  . GLN D 3 41  ? 321.221 325.534 419.866 1.00 83.68  ? 41  GLN L CA  1 
ATOM 3164 C C   . GLN D 3 41  ? 321.596 326.201 421.180 1.00 83.68  ? 41  GLN L C   1 
ATOM 3165 O O   . GLN D 3 41  ? 321.550 327.430 421.291 1.00 83.68  ? 41  GLN L O   1 
ATOM 3166 C CB  . GLN D 3 41  ? 322.232 325.908 418.782 1.00 83.68  ? 41  GLN L CB  1 
ATOM 3167 C CG  . GLN D 3 41  ? 323.643 325.432 419.080 1.00 83.68  ? 41  GLN L CG  1 
ATOM 3168 C CD  . GLN D 3 41  ? 324.628 325.811 417.998 1.00 83.68  ? 41  GLN L CD  1 
ATOM 3169 O OE1 . GLN D 3 41  ? 325.800 325.444 418.052 1.00 83.68  ? 41  GLN L OE1 1 
ATOM 3170 N NE2 . GLN D 3 41  ? 324.158 326.559 417.012 1.00 83.68  ? 41  GLN L NE2 1 
ATOM 3171 N N   . LYS D 3 42  ? 321.963 325.392 422.167 1.00 88.96  ? 42  LYS L N   1 
ATOM 3172 C CA  . LYS D 3 42  ? 322.500 325.887 423.423 1.00 88.96  ? 42  LYS L CA  1 
ATOM 3173 C C   . LYS D 3 42  ? 324.023 325.947 423.329 1.00 88.96  ? 42  LYS L C   1 
ATOM 3174 O O   . LYS D 3 42  ? 324.606 325.855 422.246 1.00 88.96  ? 42  LYS L O   1 
ATOM 3175 C CB  . LYS D 3 42  ? 322.037 325.012 424.585 1.00 88.96  ? 42  LYS L CB  1 
ATOM 3176 C CG  . LYS D 3 42  ? 320.531 324.928 424.741 1.00 88.96  ? 42  LYS L CG  1 
ATOM 3177 C CD  . LYS D 3 42  ? 320.156 324.590 426.171 1.00 88.96  ? 42  LYS L CD  1 
ATOM 3178 C CE  . LYS D 3 42  ? 319.128 323.476 426.221 1.00 88.96  ? 42  LYS L CE  1 
ATOM 3179 N NZ  . LYS D 3 42  ? 319.073 322.838 427.564 1.00 88.96  ? 42  LYS L NZ  1 
ATOM 3180 N N   . GLN D 3 43  ? 324.688 326.111 424.473 1.00 93.25  ? 43  GLN L N   1 
ATOM 3181 C CA  . GLN D 3 43  ? 326.145 326.114 424.498 1.00 93.25  ? 43  GLN L CA  1 
ATOM 3182 C C   . GLN D 3 43  ? 326.743 324.739 424.229 1.00 93.25  ? 43  GLN L C   1 
ATOM 3183 O O   . GLN D 3 43  ? 327.962 324.637 424.057 1.00 93.25  ? 43  GLN L O   1 
ATOM 3184 C CB  . GLN D 3 43  ? 326.645 326.647 425.840 1.00 93.25  ? 43  GLN L CB  1 
ATOM 3185 C CG  . GLN D 3 43  ? 326.173 328.056 426.141 1.00 93.25  ? 43  GLN L CG  1 
ATOM 3186 C CD  . GLN D 3 43  ? 326.258 328.963 424.930 1.00 93.25  ? 43  GLN L CD  1 
ATOM 3187 O OE1 . GLN D 3 43  ? 327.345 329.244 424.427 1.00 93.25  ? 43  GLN L OE1 1 
ATOM 3188 N NE2 . GLN D 3 43  ? 325.108 329.423 424.451 1.00 93.25  ? 43  GLN L NE2 1 
ATOM 3189 N N   . GLY D 3 44  ? 325.922 323.688 424.188 1.00 92.02  ? 44  GLY L N   1 
ATOM 3190 C CA  . GLY D 3 44  ? 326.405 322.359 423.859 1.00 92.02  ? 44  GLY L CA  1 
ATOM 3191 C C   . GLY D 3 44  ? 326.722 322.158 422.393 1.00 92.02  ? 44  GLY L C   1 
ATOM 3192 O O   . GLY D 3 44  ? 327.235 321.094 422.030 1.00 92.02  ? 44  GLY L O   1 
ATOM 3193 N N   . LYS D 3 45  ? 326.412 323.142 421.550 1.00 89.36  ? 45  LYS L N   1 
ATOM 3194 C CA  . LYS D 3 45  ? 326.781 323.160 420.135 1.00 89.36  ? 45  LYS L CA  1 
ATOM 3195 C C   . LYS D 3 45  ? 326.147 322.023 419.342 1.00 89.36  ? 45  LYS L C   1 
ATOM 3196 O O   . LYS D 3 45  ? 326.636 321.669 418.267 1.00 89.36  ? 45  LYS L O   1 
ATOM 3197 C CB  . LYS D 3 45  ? 328.304 323.141 419.958 1.00 89.36  ? 45  LYS L CB  1 
ATOM 3198 C CG  . LYS D 3 45  ? 329.046 324.156 420.815 1.00 89.36  ? 45  LYS L CG  1 
ATOM 3199 C CD  . LYS D 3 45  ? 330.539 323.877 420.823 1.00 89.36  ? 45  LYS L CD  1 
ATOM 3200 C CE  . LYS D 3 45  ? 331.171 324.276 422.145 1.00 89.36  ? 45  LYS L CE  1 
ATOM 3201 N NZ  . LYS D 3 45  ? 332.500 323.637 422.335 1.00 89.36  ? 45  LYS L NZ  1 
ATOM 3202 N N   . SER D 3 46  ? 325.068 321.437 419.843 1.00 83.36  ? 46  SER L N   1 
ATOM 3203 C CA  . SER D 3 46  ? 324.310 320.434 419.097 1.00 83.36  ? 46  SER L CA  1 
ATOM 3204 C C   . SER D 3 46  ? 322.874 320.912 418.956 1.00 83.36  ? 46  SER L C   1 
ATOM 3205 O O   . SER D 3 46  ? 322.125 320.908 419.951 1.00 83.36  ? 46  SER L O   1 
ATOM 3206 C CB  . SER D 3 46  ? 324.361 319.077 419.796 1.00 83.36  ? 46  SER L CB  1 
ATOM 3207 O OG  . SER D 3 46  ? 323.765 319.144 421.079 1.00 83.36  ? 46  SER L OG  1 
ATOM 3208 N N   . PRO D 3 47  ? 322.449 321.362 417.776 1.00 76.48  ? 47  PRO L N   1 
ATOM 3209 C CA  . PRO D 3 47  ? 321.091 321.897 417.632 1.00 76.48  ? 47  PRO L CA  1 
ATOM 3210 C C   . PRO D 3 47  ? 320.015 320.850 417.881 1.00 76.48  ? 47  PRO L C   1 
ATOM 3211 O O   . PRO D 3 47  ? 320.170 319.667 417.574 1.00 76.48  ? 47  PRO L O   1 
ATOM 3212 C CB  . PRO D 3 47  ? 321.060 322.384 416.180 1.00 76.48  ? 47  PRO L CB  1 
ATOM 3213 C CG  . PRO D 3 47  ? 322.484 322.666 415.856 1.00 76.48  ? 47  PRO L CG  1 
ATOM 3214 C CD  . PRO D 3 47  ? 323.273 321.623 416.585 1.00 76.48  ? 47  PRO L CD  1 
ATOM 3215 N N   . GLN D 3 48  ? 318.904 321.312 418.455 1.00 75.93  ? 48  GLN L N   1 
ATOM 3216 C CA  . GLN D 3 48  ? 317.682 320.533 418.592 1.00 75.93  ? 48  GLN L CA  1 
ATOM 3217 C C   . GLN D 3 48  ? 316.689 320.956 417.520 1.00 75.93  ? 48  GLN L C   1 
ATOM 3218 O O   . GLN D 3 48  ? 316.917 321.912 416.777 1.00 75.93  ? 48  GLN L O   1 
ATOM 3219 C CB  . GLN D 3 48  ? 317.039 320.699 419.978 1.00 75.93  ? 48  GLN L CB  1 
ATOM 3220 C CG  . GLN D 3 48  ? 317.978 320.563 421.165 1.00 75.93  ? 48  GLN L CG  1 
ATOM 3221 C CD  . GLN D 3 48  ? 318.888 319.354 421.063 1.00 75.93  ? 48  GLN L CD  1 
ATOM 3222 O OE1 . GLN D 3 48  ? 319.985 319.427 420.517 1.00 75.93  ? 48  GLN L OE1 1 
ATOM 3223 N NE2 . GLN D 3 48  ? 318.431 318.228 421.599 1.00 75.93  ? 48  GLN L NE2 1 
ATOM 3224 N N   . LEU D 3 49  ? 315.573 320.237 417.456 1.00 69.36  ? 49  LEU L N   1 
ATOM 3225 C CA  . LEU D 3 49  ? 314.540 320.477 416.460 1.00 69.36  ? 49  LEU L CA  1 
ATOM 3226 C C   . LEU D 3 49  ? 313.265 320.978 417.123 1.00 69.36  ? 49  LEU L C   1 
ATOM 3227 O O   . LEU D 3 49  ? 312.892 320.519 418.206 1.00 69.36  ? 49  LEU L O   1 
ATOM 3228 C CB  . LEU D 3 49  ? 314.247 319.208 415.659 1.00 69.36  ? 49  LEU L CB  1 
ATOM 3229 C CG  . LEU D 3 49  ? 312.989 319.243 414.793 1.00 69.36  ? 49  LEU L CG  1 
ATOM 3230 C CD1 . LEU D 3 49  ? 313.247 320.019 413.524 1.00 69.36  ? 49  LEU L CD1 1 
ATOM 3231 C CD2 . LEU D 3 49  ? 312.524 317.837 414.478 1.00 69.36  ? 49  LEU L CD2 1 
ATOM 3232 N N   . LEU D 3 50  ? 312.603 321.927 416.464 1.00 71.68  ? 50  LEU L N   1 
ATOM 3233 C CA  . LEU D 3 50  ? 311.347 322.485 416.936 1.00 71.68  ? 50  LEU L CA  1 
ATOM 3234 C C   . LEU D 3 50  ? 310.393 322.620 415.755 1.00 71.68  ? 50  LEU L C   1 
ATOM 3235 O O   . LEU D 3 50  ? 310.816 322.757 414.605 1.00 71.68  ? 50  LEU L O   1 
ATOM 3236 C CB  . LEU D 3 50  ? 311.558 323.857 417.590 1.00 71.68  ? 50  LEU L CB  1 
ATOM 3237 C CG  . LEU D 3 50  ? 312.562 323.977 418.740 1.00 71.68  ? 50  LEU L CG  1 
ATOM 3238 C CD1 . LEU D 3 50  ? 312.739 325.431 419.134 1.00 71.68  ? 50  LEU L CD1 1 
ATOM 3239 C CD2 . LEU D 3 50  ? 312.140 323.154 419.933 1.00 71.68  ? 50  LEU L CD2 1 
ATOM 3240 N N   . VAL D 3 51  ? 309.096 322.568 416.051 1.00 71.45  ? 51  VAL L N   1 
ATOM 3241 C CA  . VAL D 3 51  ? 308.048 322.991 415.123 1.00 71.45  ? 51  VAL L CA  1 
ATOM 3242 C C   . VAL D 3 51  ? 308.027 322.166 413.836 1.00 71.45  ? 51  VAL L C   1 
ATOM 3243 O O   . VAL D 3 51  ? 307.048 321.472 413.550 1.00 71.45  ? 51  VAL L O   1 
ATOM 3244 C CB  . VAL D 3 51  ? 308.192 324.491 414.808 1.00 71.45  ? 51  VAL L CB  1 
ATOM 3245 C CG1 . VAL D 3 51  ? 306.980 324.988 414.054 1.00 71.45  ? 51  VAL L CG1 1 
ATOM 3246 C CG2 . VAL D 3 51  ? 308.369 325.282 416.093 1.00 71.45  ? 51  VAL L CG2 1 
ATOM 3247 N N   . TYR D 3 52  ? 309.068 322.313 413.021 1.00 66.01  ? 52  TYR L N   1 
ATOM 3248 C CA  . TYR D 3 52  ? 309.367 321.570 411.792 1.00 66.01  ? 52  TYR L CA  1 
ATOM 3249 C C   . TYR D 3 52  ? 308.305 321.669 410.700 1.00 66.01  ? 52  TYR L C   1 
ATOM 3250 O O   . TYR D 3 52  ? 308.485 321.065 409.637 1.00 66.01  ? 52  TYR L O   1 
ATOM 3251 C CB  . TYR D 3 52  ? 309.658 320.079 412.028 1.00 66.01  ? 52  TYR L CB  1 
ATOM 3252 C CG  . TYR D 3 52  ? 308.517 319.220 412.528 1.00 66.01  ? 52  TYR L CG  1 
ATOM 3253 C CD1 . TYR D 3 52  ? 308.410 318.879 413.865 1.00 66.01  ? 52  TYR L CD1 1 
ATOM 3254 C CD2 . TYR D 3 52  ? 307.538 318.765 411.659 1.00 66.01  ? 52  TYR L CD2 1 
ATOM 3255 C CE1 . TYR D 3 52  ? 307.370 318.098 414.316 1.00 66.01  ? 52  TYR L CE1 1 
ATOM 3256 C CE2 . TYR D 3 52  ? 306.493 318.000 412.102 1.00 66.01  ? 52  TYR L CE2 1 
ATOM 3257 C CZ  . TYR D 3 52  ? 306.415 317.660 413.429 1.00 66.01  ? 52  TYR L CZ  1 
ATOM 3258 O OH  . TYR D 3 52  ? 305.370 316.883 413.868 1.00 66.01  ? 52  TYR L OH  1 
ATOM 3259 N N   . HIS D 3 53  ? 307.203 322.383 410.912 1.00 62.72  ? 53  HIS L N   1 
ATOM 3260 C CA  . HIS D 3 53  ? 306.301 322.640 409.794 1.00 62.72  ? 53  HIS L CA  1 
ATOM 3261 C C   . HIS D 3 53  ? 305.729 324.046 409.874 1.00 62.72  ? 53  HIS L C   1 
ATOM 3262 O O   . HIS D 3 53  ? 304.685 324.332 409.280 1.00 62.72  ? 53  HIS L O   1 
ATOM 3263 C CB  . HIS D 3 53  ? 305.175 321.608 409.748 1.00 62.72  ? 53  HIS L CB  1 
ATOM 3264 C CG  . HIS D 3 53  ? 304.543 321.469 408.397 1.00 62.72  ? 53  HIS L CG  1 
ATOM 3265 N ND1 . HIS D 3 53  ? 305.220 320.966 407.307 1.00 62.72  ? 53  HIS L ND1 1 
ATOM 3266 C CD2 . HIS D 3 53  ? 303.299 321.770 407.958 1.00 62.72  ? 53  HIS L CD2 1 
ATOM 3267 C CE1 . HIS D 3 53  ? 304.419 320.962 406.257 1.00 62.72  ? 53  HIS L CE1 1 
ATOM 3268 N NE2 . HIS D 3 53  ? 303.247 321.444 406.625 1.00 62.72  ? 53  HIS L NE2 1 
ATOM 3269 N N   . ALA D 3 54  ? 306.386 324.909 410.649 1.00 69.57  ? 54  ALA L N   1 
ATOM 3270 C CA  . ALA D 3 54  ? 305.989 326.296 410.863 1.00 69.57  ? 54  ALA L CA  1 
ATOM 3271 C C   . ALA D 3 54  ? 304.681 326.393 411.640 1.00 69.57  ? 54  ALA L C   1 
ATOM 3272 O O   . ALA D 3 54  ? 304.265 327.490 412.021 1.00 69.57  ? 54  ALA L O   1 
ATOM 3273 C CB  . ALA D 3 54  ? 305.877 327.046 409.533 1.00 69.57  ? 54  ALA L CB  1 
ATOM 3274 N N   . GLU D 3 55  ? 304.022 325.258 411.881 1.00 73.11  ? 55  GLU L N   1 
ATOM 3275 C CA  . GLU D 3 55  ? 302.834 325.228 412.729 1.00 73.11  ? 55  GLU L CA  1 
ATOM 3276 C C   . GLU D 3 55  ? 302.801 324.073 413.720 1.00 73.11  ? 55  GLU L C   1 
ATOM 3277 O O   . GLU D 3 55  ? 302.135 324.198 414.752 1.00 73.11  ? 55  GLU L O   1 
ATOM 3278 C CB  . GLU D 3 55  ? 301.559 325.171 411.876 1.00 73.11  ? 55  GLU L CB  1 
ATOM 3279 C CG  . GLU D 3 55  ? 301.495 326.191 410.749 1.00 73.11  ? 55  GLU L CG  1 
ATOM 3280 C CD  . GLU D 3 55  ? 300.561 327.343 411.056 1.00 73.11  ? 55  GLU L CD  1 
ATOM 3281 O OE1 . GLU D 3 55  ? 300.104 327.448 412.212 1.00 73.11  ? 55  GLU L OE1 1 
ATOM 3282 O OE2 . GLU D 3 55  ? 300.285 328.145 410.139 1.00 73.11  ? 55  GLU L OE2 1 
ATOM 3283 N N   . THR D 3 56  ? 303.488 322.966 413.463 1.00 73.74  ? 56  THR L N   1 
ATOM 3284 C CA  . THR D 3 56  ? 303.422 321.793 414.319 1.00 73.74  ? 56  THR L CA  1 
ATOM 3285 C C   . THR D 3 56  ? 304.448 321.921 415.441 1.00 73.74  ? 56  THR L C   1 
ATOM 3286 O O   . THR D 3 56  ? 304.983 322.999 415.701 1.00 73.74  ? 56  THR L O   1 
ATOM 3287 C CB  . THR D 3 56  ? 303.633 320.523 413.504 1.00 73.74  ? 56  THR L CB  1 
ATOM 3288 O OG1 . THR D 3 56  ? 305.009 320.434 413.125 1.00 73.74  ? 56  THR L OG1 1 
ATOM 3289 C CG2 . THR D 3 56  ? 302.767 320.540 412.261 1.00 73.74  ? 56  THR L CG2 1 
ATOM 3290 N N   . LEU D 3 57  ? 304.711 320.820 416.141 1.00 78.73  ? 57  LEU L N   1 
ATOM 3291 C CA  . LEU D 3 57  ? 305.621 320.846 417.273 1.00 78.73  ? 57  LEU L CA  1 
ATOM 3292 C C   . LEU D 3 57  ? 306.290 319.487 417.405 1.00 78.73  ? 57  LEU L C   1 
ATOM 3293 O O   . LEU D 3 57  ? 305.721 318.462 417.023 1.00 78.73  ? 57  LEU L O   1 
ATOM 3294 C CB  . LEU D 3 57  ? 304.877 321.203 418.562 1.00 78.73  ? 57  LEU L CB  1 
ATOM 3295 C CG  . LEU D 3 57  ? 305.714 321.773 419.699 1.00 78.73  ? 57  LEU L CG  1 
ATOM 3296 C CD1 . LEU D 3 57  ? 306.204 323.155 419.317 1.00 78.73  ? 57  LEU L CD1 1 
ATOM 3297 C CD2 . LEU D 3 57  ? 304.902 321.822 420.976 1.00 78.73  ? 57  LEU L CD2 1 
ATOM 3298 N N   . ALA D 3 58  ? 307.504 319.485 417.951 1.00 85.47  ? 58  ALA L N   1 
ATOM 3299 C CA  . ALA D 3 58  ? 308.235 318.243 418.139 1.00 85.47  ? 58  ALA L CA  1 
ATOM 3300 C C   . ALA D 3 58  ? 307.779 317.537 419.416 1.00 85.47  ? 58  ALA L C   1 
ATOM 3301 O O   . ALA D 3 58  ? 306.889 317.999 420.133 1.00 85.47  ? 58  ALA L O   1 
ATOM 3302 C CB  . ALA D 3 58  ? 309.739 318.503 418.177 1.00 85.47  ? 58  ALA L CB  1 
ATOM 3303 N N   . ASP D 3 59  ? 308.406 316.392 419.693 1.00 92.80  ? 59  ASP L N   1 
ATOM 3304 C CA  . ASP D 3 59  ? 307.966 315.552 420.804 1.00 92.80  ? 59  ASP L CA  1 
ATOM 3305 C C   . ASP D 3 59  ? 308.343 316.152 422.154 1.00 92.80  ? 59  ASP L C   1 
ATOM 3306 O O   . ASP D 3 59  ? 307.516 316.209 423.072 1.00 92.80  ? 59  ASP L O   1 
ATOM 3307 C CB  . ASP D 3 59  ? 308.553 314.148 420.660 1.00 92.80  ? 59  ASP L CB  1 
ATOM 3308 C CG  . ASP D 3 59  ? 307.723 313.262 419.756 1.00 92.80  ? 59  ASP L CG  1 
ATOM 3309 O OD1 . ASP D 3 59  ? 306.517 313.091 420.033 1.00 92.80  ? 59  ASP L OD1 1 
ATOM 3310 O OD2 . ASP D 3 59  ? 308.274 312.737 418.767 1.00 92.80  ? 59  ASP L OD2 1 
ATOM 3311 N N   . GLY D 3 60  ? 309.589 316.602 422.299 1.00 92.80  ? 60  GLY L N   1 
ATOM 3312 C CA  . GLY D 3 60  ? 310.066 317.062 423.591 1.00 92.80  ? 60  GLY L CA  1 
ATOM 3313 C C   . GLY D 3 60  ? 309.752 318.501 423.931 1.00 92.80  ? 60  GLY L C   1 
ATOM 3314 O O   . GLY D 3 60  ? 310.096 318.952 425.027 1.00 92.80  ? 60  GLY L O   1 
ATOM 3315 N N   . VAL D 3 61  ? 309.110 319.227 423.027 1.00 91.37  ? 61  VAL L N   1 
ATOM 3316 C CA  . VAL D 3 61  ? 308.877 320.660 423.239 1.00 91.37  ? 61  VAL L CA  1 
ATOM 3317 C C   . VAL D 3 61  ? 307.771 320.845 424.271 1.00 91.37  ? 61  VAL L C   1 
ATOM 3318 O O   . VAL D 3 61  ? 306.719 320.188 424.171 1.00 91.37  ? 61  VAL L O   1 
ATOM 3319 C CB  . VAL D 3 61  ? 308.521 321.334 421.916 1.00 91.37  ? 61  VAL L CB  1 
ATOM 3320 C CG1 . VAL D 3 61  ? 308.476 322.840 422.079 1.00 91.37  ? 61  VAL L CG1 1 
ATOM 3321 C CG2 . VAL D 3 61  ? 309.519 320.938 420.851 1.00 91.37  ? 61  VAL L CG2 1 
ATOM 3322 N N   . PRO D 3 62  ? 307.949 321.717 425.263 1.00 94.72  ? 62  PRO L N   1 
ATOM 3323 C CA  . PRO D 3 62  ? 306.954 321.869 426.332 1.00 94.72  ? 62  PRO L CA  1 
ATOM 3324 C C   . PRO D 3 62  ? 305.723 322.682 425.959 1.00 94.72  ? 62  PRO L C   1 
ATOM 3325 O O   . PRO D 3 62  ? 305.006 323.117 426.863 1.00 94.72  ? 62  PRO L O   1 
ATOM 3326 C CB  . PRO D 3 62  ? 307.756 322.582 427.431 1.00 94.72  ? 62  PRO L CB  1 
ATOM 3327 C CG  . PRO D 3 62  ? 308.777 323.357 426.688 1.00 94.72  ? 62  PRO L CG  1 
ATOM 3328 C CD  . PRO D 3 62  ? 309.173 322.488 425.537 1.00 94.72  ? 62  PRO L CD  1 
ATOM 3329 N N   . SER D 3 63  ? 305.477 322.920 424.671 1.00 94.74  ? 63  SER L N   1 
ATOM 3330 C CA  . SER D 3 63  ? 304.324 323.634 424.124 1.00 94.74  ? 63  SER L CA  1 
ATOM 3331 C C   . SER D 3 63  ? 304.352 325.129 424.409 1.00 94.74  ? 63  SER L C   1 
ATOM 3332 O O   . SER D 3 63  ? 303.442 325.841 423.970 1.00 94.74  ? 63  SER L O   1 
ATOM 3333 C CB  . SER D 3 63  ? 302.984 323.068 424.619 1.00 94.74  ? 63  SER L CB  1 
ATOM 3334 O OG  . SER D 3 63  ? 302.723 323.474 425.950 1.00 94.74  ? 63  SER L OG  1 
ATOM 3335 N N   . ARG D 3 64  ? 305.352 325.634 425.134 1.00 96.31  ? 64  ARG L N   1 
ATOM 3336 C CA  . ARG D 3 64  ? 305.526 327.077 425.232 1.00 96.31  ? 64  ARG L CA  1 
ATOM 3337 C C   . ARG D 3 64  ? 305.965 327.678 423.907 1.00 96.31  ? 64  ARG L C   1 
ATOM 3338 O O   . ARG D 3 64  ? 305.802 328.885 423.700 1.00 96.31  ? 64  ARG L O   1 
ATOM 3339 C CB  . ARG D 3 64  ? 306.544 327.416 426.318 1.00 96.31  ? 64  ARG L CB  1 
ATOM 3340 C CG  . ARG D 3 64  ? 306.018 327.270 427.730 1.00 96.31  ? 64  ARG L CG  1 
ATOM 3341 C CD  . ARG D 3 64  ? 307.146 327.424 428.733 1.00 96.31  ? 64  ARG L CD  1 
ATOM 3342 N NE  . ARG D 3 64  ? 308.172 326.403 428.560 1.00 96.31  ? 64  ARG L NE  1 
ATOM 3343 C CZ  . ARG D 3 64  ? 309.474 326.651 428.531 1.00 96.31  ? 64  ARG L CZ  1 
ATOM 3344 N NH1 . ARG D 3 64  ? 309.944 327.883 428.625 1.00 96.31  ? 64  ARG L NH1 1 
ATOM 3345 N NH2 . ARG D 3 64  ? 310.325 325.639 428.400 1.00 96.31  ? 64  ARG L NH2 1 
ATOM 3346 N N   . PHE D 3 65  ? 306.520 326.864 423.016 1.00 91.36  ? 65  PHE L N   1 
ATOM 3347 C CA  . PHE D 3 65  ? 306.910 327.297 421.684 1.00 91.36  ? 65  PHE L CA  1 
ATOM 3348 C C   . PHE D 3 65  ? 305.769 327.039 420.711 1.00 91.36  ? 65  PHE L C   1 
ATOM 3349 O O   . PHE D 3 65  ? 305.123 325.989 420.757 1.00 91.36  ? 65  PHE L O   1 
ATOM 3350 C CB  . PHE D 3 65  ? 308.165 326.553 421.222 1.00 91.36  ? 65  PHE L CB  1 
ATOM 3351 C CG  . PHE D 3 65  ? 309.336 326.687 422.154 1.00 91.36  ? 65  PHE L CG  1 
ATOM 3352 C CD1 . PHE D 3 65  ? 309.404 325.942 423.319 1.00 91.36  ? 65  PHE L CD1 1 
ATOM 3353 C CD2 . PHE D 3 65  ? 310.381 327.539 421.854 1.00 91.36  ? 65  PHE L CD2 1 
ATOM 3354 C CE1 . PHE D 3 65  ? 310.479 326.058 424.173 1.00 91.36  ? 65  PHE L CE1 1 
ATOM 3355 C CE2 . PHE D 3 65  ? 311.462 327.655 422.705 1.00 91.36  ? 65  PHE L CE2 1 
ATOM 3356 C CZ  . PHE D 3 65  ? 311.509 326.914 423.866 1.00 91.36  ? 65  PHE L CZ  1 
ATOM 3357 N N   . SER D 3 66  ? 305.521 328.004 419.831 1.00 85.85  ? 66  SER L N   1 
ATOM 3358 C CA  . SER D 3 66  ? 304.481 327.851 418.825 1.00 85.85  ? 66  SER L CA  1 
ATOM 3359 C C   . SER D 3 66  ? 304.786 328.776 417.658 1.00 85.85  ? 66  SER L C   1 
ATOM 3360 O O   . SER D 3 66  ? 305.215 329.914 417.858 1.00 85.85  ? 66  SER L O   1 
ATOM 3361 C CB  . SER D 3 66  ? 303.094 328.154 419.402 1.00 85.85  ? 66  SER L CB  1 
ATOM 3362 O OG  . SER D 3 66  ? 302.808 329.540 419.351 1.00 85.85  ? 66  SER L OG  1 
ATOM 3363 N N   . GLY D 3 67  ? 304.559 328.280 416.446 1.00 79.40  ? 67  GLY L N   1 
ATOM 3364 C CA  . GLY D 3 67  ? 304.804 329.063 415.254 1.00 79.40  ? 67  GLY L CA  1 
ATOM 3365 C C   . GLY D 3 67  ? 303.552 329.293 414.437 1.00 79.40  ? 67  GLY L C   1 
ATOM 3366 O O   . GLY D 3 67  ? 302.539 328.618 414.638 1.00 79.40  ? 67  GLY L O   1 
ATOM 3367 N N   . SER D 3 68  ? 303.608 330.243 413.512 1.00 77.02  ? 68  SER L N   1 
ATOM 3368 C CA  . SER D 3 68  ? 302.459 330.593 412.689 1.00 77.02  ? 68  SER L CA  1 
ATOM 3369 C C   . SER D 3 68  ? 302.970 331.266 411.422 1.00 77.02  ? 68  SER L C   1 
ATOM 3370 O O   . SER D 3 68  ? 304.163 331.212 411.106 1.00 77.02  ? 68  SER L O   1 
ATOM 3371 C CB  . SER D 3 68  ? 301.487 331.486 413.463 1.00 77.02  ? 68  SER L CB  1 
ATOM 3372 O OG  . SER D 3 68  ? 302.166 332.575 414.062 1.00 77.02  ? 68  SER L OG  1 
ATOM 3373 N N   . GLY D 3 69  ? 302.064 331.899 410.691 1.00 73.14  ? 69  GLY L N   1 
ATOM 3374 C CA  . GLY D 3 69  ? 302.409 332.589 409.469 1.00 73.14  ? 69  GLY L CA  1 
ATOM 3375 C C   . GLY D 3 69  ? 302.164 331.732 408.239 1.00 73.14  ? 69  GLY L C   1 
ATOM 3376 O O   . GLY D 3 69  ? 302.082 330.504 408.299 1.00 73.14  ? 69  GLY L O   1 
ATOM 3377 N N   . SER D 3 70  ? 302.041 332.404 407.098 1.00 71.16  ? 70  SER L N   1 
ATOM 3378 C CA  . SER D 3 70  ? 301.818 331.719 405.836 1.00 71.16  ? 70  SER L CA  1 
ATOM 3379 C C   . SER D 3 70  ? 302.452 332.523 404.715 1.00 71.16  ? 70  SER L C   1 
ATOM 3380 O O   . SER D 3 70  ? 302.696 333.725 404.845 1.00 71.16  ? 70  SER L O   1 
ATOM 3381 C CB  . SER D 3 70  ? 300.325 331.510 405.563 1.00 71.16  ? 70  SER L CB  1 
ATOM 3382 O OG  . SER D 3 70  ? 299.667 332.746 405.353 1.00 71.16  ? 70  SER L OG  1 
ATOM 3383 N N   . GLY D 3 71  ? 302.714 331.842 403.605 1.00 68.75  ? 71  GLY L N   1 
ATOM 3384 C CA  . GLY D 3 71  ? 303.295 332.494 402.452 1.00 68.75  ? 71  GLY L CA  1 
ATOM 3385 C C   . GLY D 3 71  ? 304.787 332.711 402.579 1.00 68.75  ? 71  GLY L C   1 
ATOM 3386 O O   . GLY D 3 71  ? 305.564 331.752 402.560 1.00 68.75  ? 71  GLY L O   1 
ATOM 3387 N N   . THR D 3 72  ? 305.201 333.969 402.712 1.00 72.19  ? 72  THR L N   1 
ATOM 3388 C CA  . THR D 3 72  ? 306.609 334.322 402.807 1.00 72.19  ? 72  THR L CA  1 
ATOM 3389 C C   . THR D 3 72  ? 306.993 334.891 404.164 1.00 72.19  ? 72  THR L C   1 
ATOM 3390 O O   . THR D 3 72  ? 308.162 335.236 404.365 1.00 72.19  ? 72  THR L O   1 
ATOM 3391 C CB  . THR D 3 72  ? 306.974 335.328 401.710 1.00 72.19  ? 72  THR L CB  1 
ATOM 3392 O OG1 . THR D 3 72  ? 306.276 336.556 401.941 1.00 72.19  ? 72  THR L OG1 1 
ATOM 3393 C CG2 . THR D 3 72  ? 306.579 334.789 400.349 1.00 72.19  ? 72  THR L CG2 1 
ATOM 3394 N N   . GLN D 3 73  ? 306.051 335.002 405.096 1.00 73.80  ? 73  GLN L N   1 
ATOM 3395 C CA  . GLN D 3 73  ? 306.305 335.560 406.419 1.00 73.80  ? 73  GLN L CA  1 
ATOM 3396 C C   . GLN D 3 73  ? 306.015 334.494 407.464 1.00 73.80  ? 73  GLN L C   1 
ATOM 3397 O O   . GLN D 3 73  ? 304.928 333.908 407.469 1.00 73.80  ? 73  GLN L O   1 
ATOM 3398 C CB  . GLN D 3 73  ? 305.443 336.799 406.664 1.00 73.80  ? 73  GLN L CB  1 
ATOM 3399 C CG  . GLN D 3 73  ? 305.702 337.486 407.993 1.00 73.80  ? 73  GLN L CG  1 
ATOM 3400 C CD  . GLN D 3 73  ? 306.857 338.464 407.928 1.00 73.80  ? 73  GLN L CD  1 
ATOM 3401 O OE1 . GLN D 3 73  ? 307.126 339.053 406.883 1.00 73.80  ? 73  GLN L OE1 1 
ATOM 3402 N NE2 . GLN D 3 73  ? 307.547 338.642 409.048 1.00 73.80  ? 73  GLN L NE2 1 
ATOM 3403 N N   . TYR D 3 74  ? 306.979 334.248 408.346 1.00 70.31  ? 74  TYR L N   1 
ATOM 3404 C CA  . TYR D 3 74  ? 306.833 333.242 409.387 1.00 70.31  ? 74  TYR L CA  1 
ATOM 3405 C C   . TYR D 3 74  ? 307.363 333.800 410.698 1.00 70.31  ? 74  TYR L C   1 
ATOM 3406 O O   . TYR D 3 74  ? 308.149 334.748 410.719 1.00 70.31  ? 74  TYR L O   1 
ATOM 3407 C CB  . TYR D 3 74  ? 307.563 331.946 409.028 1.00 70.31  ? 74  TYR L CB  1 
ATOM 3408 C CG  . TYR D 3 74  ? 307.015 331.259 407.802 1.00 70.31  ? 74  TYR L CG  1 
ATOM 3409 C CD1 . TYR D 3 74  ? 307.498 331.564 406.540 1.00 70.31  ? 74  TYR L CD1 1 
ATOM 3410 C CD2 . TYR D 3 74  ? 306.015 330.307 407.907 1.00 70.31  ? 74  TYR L CD2 1 
ATOM 3411 C CE1 . TYR D 3 74  ? 307.001 330.938 405.419 1.00 70.31  ? 74  TYR L CE1 1 
ATOM 3412 C CE2 . TYR D 3 74  ? 305.513 329.677 406.792 1.00 70.31  ? 74  TYR L CE2 1 
ATOM 3413 C CZ  . TYR D 3 74  ? 306.009 329.996 405.552 1.00 70.31  ? 74  TYR L CZ  1 
ATOM 3414 O OH  . TYR D 3 74  ? 305.508 329.369 404.437 1.00 70.31  ? 74  TYR L OH  1 
ATOM 3415 N N   . SER D 3 75  ? 306.919 333.199 411.799 1.00 77.20  ? 75  SER L N   1 
ATOM 3416 C CA  . SER D 3 75  ? 307.277 333.693 413.118 1.00 77.20  ? 75  SER L CA  1 
ATOM 3417 C C   . SER D 3 75  ? 307.341 332.539 414.104 1.00 77.20  ? 75  SER L C   1 
ATOM 3418 O O   . SER D 3 75  ? 306.768 331.470 413.882 1.00 77.20  ? 75  SER L O   1 
ATOM 3419 C CB  . SER D 3 75  ? 306.280 334.748 413.608 1.00 77.20  ? 75  SER L CB  1 
ATOM 3420 O OG  . SER D 3 75  ? 305.178 334.137 414.254 1.00 77.20  ? 75  SER L OG  1 
ATOM 3421 N N   . LEU D 3 76  ? 308.053 332.775 415.202 1.00 79.54  ? 76  LEU L N   1 
ATOM 3422 C CA  . LEU D 3 76  ? 308.138 331.843 416.317 1.00 79.54  ? 76  LEU L CA  1 
ATOM 3423 C C   . LEU D 3 76  ? 307.730 332.579 417.583 1.00 79.54  ? 76  LEU L C   1 
ATOM 3424 O O   . LEU D 3 76  ? 308.188 333.700 417.821 1.00 79.54  ? 76  LEU L O   1 
ATOM 3425 C CB  . LEU D 3 76  ? 309.552 331.276 416.460 1.00 79.54  ? 76  LEU L CB  1 
ATOM 3426 C CG  . LEU D 3 76  ? 309.772 330.263 417.582 1.00 79.54  ? 76  LEU L CG  1 
ATOM 3427 C CD1 . LEU D 3 76  ? 308.736 329.159 417.520 1.00 79.54  ? 76  LEU L CD1 1 
ATOM 3428 C CD2 . LEU D 3 76  ? 311.171 329.685 417.520 1.00 79.54  ? 76  LEU L CD2 1 
ATOM 3429 N N   . LYS D 3 77  ? 306.875 331.957 418.389 1.00 87.34  ? 77  LYS L N   1 
ATOM 3430 C CA  . LYS D 3 77  ? 306.324 332.588 419.579 1.00 87.34  ? 77  LYS L CA  1 
ATOM 3431 C C   . LYS D 3 77  ? 306.662 331.769 420.815 1.00 87.34  ? 77  LYS L C   1 
ATOM 3432 O O   . LYS D 3 77  ? 306.572 330.538 420.800 1.00 87.34  ? 77  LYS L O   1 
ATOM 3433 C CB  . LYS D 3 77  ? 304.805 332.750 419.468 1.00 87.34  ? 77  LYS L CB  1 
ATOM 3434 C CG  . LYS D 3 77  ? 304.365 333.878 418.554 1.00 87.34  ? 77  LYS L CG  1 
ATOM 3435 C CD  . LYS D 3 77  ? 304.733 335.234 419.132 1.00 87.34  ? 77  LYS L CD  1 
ATOM 3436 C CE  . LYS D 3 77  ? 303.910 335.550 420.370 1.00 87.34  ? 77  LYS L CE  1 
ATOM 3437 N NZ  . LYS D 3 77  ? 302.509 335.061 420.245 1.00 87.34  ? 77  LYS L NZ  1 
ATOM 3438 N N   . ILE D 3 78  ? 307.048 332.461 421.883 1.00 94.49  ? 78  ILE L N   1 
ATOM 3439 C CA  . ILE D 3 78  ? 307.358 331.845 423.167 1.00 94.49  ? 78  ILE L CA  1 
ATOM 3440 C C   . ILE D 3 78  ? 306.504 332.520 424.230 1.00 94.49  ? 78  ILE L C   1 
ATOM 3441 O O   . ILE D 3 78  ? 306.508 333.750 424.346 1.00 94.49  ? 78  ILE L O   1 
ATOM 3442 C CB  . ILE D 3 78  ? 308.852 331.971 423.511 1.00 94.49  ? 78  ILE L CB  1 
ATOM 3443 C CG1 . ILE D 3 78  ? 309.661 330.882 422.811 1.00 94.49  ? 78  ILE L CG1 1 
ATOM 3444 C CG2 . ILE D 3 78  ? 309.062 331.880 425.012 1.00 94.49  ? 78  ILE L CG2 1 
ATOM 3445 C CD1 . ILE D 3 78  ? 311.150 331.061 422.958 1.00 94.49  ? 78  ILE L CD1 1 
ATOM 3446 N N   . ASN D 3 79  ? 305.776 331.720 425.002 1.00 99.62  ? 79  ASN L N   1 
ATOM 3447 C CA  . ASN D 3 79  ? 304.938 332.214 426.086 1.00 99.62  ? 79  ASN L CA  1 
ATOM 3448 C C   . ASN D 3 79  ? 305.498 331.730 427.415 1.00 99.62  ? 79  ASN L C   1 
ATOM 3449 O O   . ASN D 3 79  ? 305.856 330.556 427.547 1.00 99.62  ? 79  ASN L O   1 
ATOM 3450 C CB  . ASN D 3 79  ? 303.491 331.747 425.920 1.00 99.62  ? 79  ASN L CB  1 
ATOM 3451 C CG  . ASN D 3 79  ? 302.801 332.399 424.742 1.00 99.62  ? 79  ASN L CG  1 
ATOM 3452 O OD1 . ASN D 3 79  ? 303.169 333.496 424.322 1.00 99.62  ? 79  ASN L OD1 1 
ATOM 3453 N ND2 . ASN D 3 79  ? 301.792 331.728 424.203 1.00 99.62  ? 79  ASN L ND2 1 
ATOM 3454 N N   . SER D 3 80  ? 305.569 332.637 428.392 1.00 102.59 ? 80  SER L N   1 
ATOM 3455 C CA  . SER D 3 80  ? 306.084 332.342 429.730 1.00 102.59 ? 80  SER L CA  1 
ATOM 3456 C C   . SER D 3 80  ? 307.518 331.808 429.651 1.00 102.59 ? 80  SER L C   1 
ATOM 3457 O O   . SER D 3 80  ? 307.813 330.657 429.977 1.00 102.59 ? 80  SER L O   1 
ATOM 3458 C CB  . SER D 3 80  ? 305.164 331.362 430.469 1.00 102.59 ? 80  SER L CB  1 
ATOM 3459 O OG  . SER D 3 80  ? 305.432 330.024 430.089 1.00 102.59 ? 80  SER L OG  1 
ATOM 3460 N N   . LEU D 3 81  ? 308.400 332.693 429.190 1.00 102.81 ? 81  LEU L N   1 
ATOM 3461 C CA  . LEU D 3 81  ? 309.801 332.341 429.000 1.00 102.81 ? 81  LEU L CA  1 
ATOM 3462 C C   . LEU D 3 81  ? 310.414 331.847 430.304 1.00 102.81 ? 81  LEU L C   1 
ATOM 3463 O O   . LEU D 3 81  ? 310.151 332.389 431.381 1.00 102.81 ? 81  LEU L O   1 
ATOM 3464 C CB  . LEU D 3 81  ? 310.572 333.552 428.469 1.00 102.81 ? 81  LEU L CB  1 
ATOM 3465 C CG  . LEU D 3 81  ? 311.907 333.350 427.748 1.00 102.81 ? 81  LEU L CG  1 
ATOM 3466 C CD1 . LEU D 3 81  ? 312.212 334.564 426.899 1.00 102.81 ? 81  LEU L CD1 1 
ATOM 3467 C CD2 . LEU D 3 81  ? 313.045 333.119 428.722 1.00 102.81 ? 81  LEU L CD2 1 
ATOM 3468 N N   . GLN D 3 82  ? 311.232 330.808 430.200 1.00 103.67 ? 82  GLN L N   1 
ATOM 3469 C CA  . GLN D 3 82  ? 311.892 330.176 431.329 1.00 103.67 ? 82  GLN L CA  1 
ATOM 3470 C C   . GLN D 3 82  ? 313.404 330.245 431.153 1.00 103.67 ? 82  GLN L C   1 
ATOM 3471 O O   . GLN D 3 82  ? 313.901 330.348 430.025 1.00 103.67 ? 82  GLN L O   1 
ATOM 3472 C CB  . GLN D 3 82  ? 311.437 328.717 431.473 1.00 103.67 ? 82  GLN L CB  1 
ATOM 3473 C CG  . GLN D 3 82  ? 310.361 328.525 432.531 1.00 103.67 ? 82  GLN L CG  1 
ATOM 3474 C CD  . GLN D 3 82  ? 309.720 327.153 432.480 1.00 103.67 ? 82  GLN L CD  1 
ATOM 3475 O OE1 . GLN D 3 82  ? 310.408 326.135 432.415 1.00 103.67 ? 82  GLN L OE1 1 
ATOM 3476 N NE2 . GLN D 3 82  ? 308.393 327.121 432.512 1.00 103.67 ? 82  GLN L NE2 1 
ATOM 3477 N N   . PRO D 3 83  ? 314.168 330.196 432.250 1.00 104.82 ? 83  PRO L N   1 
ATOM 3478 C CA  . PRO D 3 83  ? 315.614 330.469 432.150 1.00 104.82 ? 83  PRO L CA  1 
ATOM 3479 C C   . PRO D 3 83  ? 316.372 329.535 431.222 1.00 104.82 ? 83  PRO L C   1 
ATOM 3480 O O   . PRO D 3 83  ? 317.351 329.968 430.601 1.00 104.82 ? 83  PRO L O   1 
ATOM 3481 C CB  . PRO D 3 83  ? 316.095 330.330 433.602 1.00 104.82 ? 83  PRO L CB  1 
ATOM 3482 C CG  . PRO D 3 83  ? 315.042 329.523 434.286 1.00 104.82 ? 83  PRO L CG  1 
ATOM 3483 C CD  . PRO D 3 83  ? 313.760 329.929 433.640 1.00 104.82 ? 83  PRO L CD  1 
ATOM 3484 N N   . GLU D 3 84  ? 315.964 328.270 431.109 1.00 104.34 ? 84  GLU L N   1 
ATOM 3485 C CA  . GLU D 3 84  ? 316.693 327.337 430.256 1.00 104.34 ? 84  GLU L CA  1 
ATOM 3486 C C   . GLU D 3 84  ? 316.547 327.658 428.775 1.00 104.34 ? 84  GLU L C   1 
ATOM 3487 O O   . GLU D 3 84  ? 317.294 327.107 427.959 1.00 104.34 ? 84  GLU L O   1 
ATOM 3488 C CB  . GLU D 3 84  ? 316.229 325.905 430.517 1.00 104.34 ? 84  GLU L CB  1 
ATOM 3489 C CG  . GLU D 3 84  ? 314.790 325.641 430.119 1.00 104.34 ? 84  GLU L CG  1 
ATOM 3490 C CD  . GLU D 3 84  ? 313.827 325.856 431.266 1.00 104.34 ? 84  GLU L CD  1 
ATOM 3491 O OE1 . GLU D 3 84  ? 313.973 326.868 431.983 1.00 104.34 ? 84  GLU L OE1 1 
ATOM 3492 O OE2 . GLU D 3 84  ? 312.925 325.013 431.450 1.00 104.34 ? 84  GLU L OE2 1 
ATOM 3493 N N   . ASP D 3 85  ? 315.606 328.529 428.407 1.00 100.94 ? 85  ASP L N   1 
ATOM 3494 C CA  . ASP D 3 85  ? 315.378 328.879 427.006 1.00 100.94 ? 85  ASP L CA  1 
ATOM 3495 C C   . ASP D 3 85  ? 316.220 330.102 426.656 1.00 100.94 ? 85  ASP L C   1 
ATOM 3496 O O   . ASP D 3 85  ? 315.727 331.222 426.514 1.00 100.94 ? 85  ASP L O   1 
ATOM 3497 C CB  . ASP D 3 85  ? 313.897 329.123 426.749 1.00 100.94 ? 85  ASP L CB  1 
ATOM 3498 C CG  . ASP D 3 85  ? 313.051 327.905 427.040 1.00 100.94 ? 85  ASP L CG  1 
ATOM 3499 O OD1 . ASP D 3 85  ? 313.602 326.785 427.044 1.00 100.94 ? 85  ASP L OD1 1 
ATOM 3500 O OD2 . ASP D 3 85  ? 311.834 328.066 427.263 1.00 100.94 ? 85  ASP L OD2 1 
ATOM 3501 N N   . PHE D 3 86  ? 317.521 329.871 426.512 1.00 98.19  ? 86  PHE L N   1 
ATOM 3502 C CA  . PHE D 3 86  ? 318.450 330.917 426.108 1.00 98.19  ? 86  PHE L CA  1 
ATOM 3503 C C   . PHE D 3 86  ? 319.506 330.317 425.196 1.00 98.19  ? 86  PHE L C   1 
ATOM 3504 O O   . PHE D 3 86  ? 320.121 329.303 425.539 1.00 98.19  ? 86  PHE L O   1 
ATOM 3505 C CB  . PHE D 3 86  ? 319.108 331.578 427.323 1.00 98.19  ? 86  PHE L CB  1 
ATOM 3506 C CG  . PHE D 3 86  ? 318.382 332.795 427.815 1.00 98.19  ? 86  PHE L CG  1 
ATOM 3507 C CD1 . PHE D 3 86  ? 318.679 334.047 427.303 1.00 98.19  ? 86  PHE L CD1 1 
ATOM 3508 C CD2 . PHE D 3 86  ? 317.402 332.690 428.786 1.00 98.19  ? 86  PHE L CD2 1 
ATOM 3509 C CE1 . PHE D 3 86  ? 318.014 335.170 427.752 1.00 98.19  ? 86  PHE L CE1 1 
ATOM 3510 C CE2 . PHE D 3 86  ? 316.733 333.809 429.238 1.00 98.19  ? 86  PHE L CE2 1 
ATOM 3511 C CZ  . PHE D 3 86  ? 317.040 335.050 428.720 1.00 98.19  ? 86  PHE L CZ  1 
ATOM 3512 N N   . GLY D 3 87  ? 319.712 330.938 424.044 1.00 90.93  ? 87  GLY L N   1 
ATOM 3513 C CA  . GLY D 3 87  ? 320.691 330.441 423.092 1.00 90.93  ? 87  GLY L CA  1 
ATOM 3514 C C   . GLY D 3 87  ? 320.450 331.038 421.716 1.00 90.93  ? 87  GLY L C   1 
ATOM 3515 O O   . GLY D 3 87  ? 319.902 332.133 421.590 1.00 90.93  ? 87  GLY L O   1 
ATOM 3516 N N   . ASN D 3 88  ? 320.870 330.292 420.700 1.00 84.30  ? 88  ASN L N   1 
ATOM 3517 C CA  . ASN D 3 88  ? 320.737 330.705 419.314 1.00 84.30  ? 88  ASN L CA  1 
ATOM 3518 C C   . ASN D 3 88  ? 319.604 329.943 418.641 1.00 84.30  ? 88  ASN L C   1 
ATOM 3519 O O   . ASN D 3 88  ? 319.377 328.762 418.917 1.00 84.30  ? 88  ASN L O   1 
ATOM 3520 C CB  . ASN D 3 88  ? 322.042 330.482 418.547 1.00 84.30  ? 88  ASN L CB  1 
ATOM 3521 C CG  . ASN D 3 88  ? 323.092 331.515 418.878 1.00 84.30  ? 88  ASN L CG  1 
ATOM 3522 O OD1 . ASN D 3 88  ? 323.171 331.996 420.007 1.00 84.30  ? 88  ASN L OD1 1 
ATOM 3523 N ND2 . ASN D 3 88  ? 323.908 331.865 417.893 1.00 84.30  ? 88  ASN L ND2 1 
ATOM 3524 N N   . TYR D 3 89  ? 318.896 330.632 417.750 1.00 79.51  ? 89  TYR L N   1 
ATOM 3525 C CA  . TYR D 3 89  ? 317.769 330.062 417.026 1.00 79.51  ? 89  TYR L CA  1 
ATOM 3526 C C   . TYR D 3 89  ? 317.994 330.222 415.531 1.00 79.51  ? 89  TYR L C   1 
ATOM 3527 O O   . TYR D 3 89  ? 318.256 331.330 415.056 1.00 79.51  ? 89  TYR L O   1 
ATOM 3528 C CB  . TYR D 3 89  ? 316.454 330.729 417.438 1.00 79.51  ? 89  TYR L CB  1 
ATOM 3529 C CG  . TYR D 3 89  ? 315.997 330.356 418.827 1.00 79.51  ? 89  TYR L CG  1 
ATOM 3530 C CD1 . TYR D 3 89  ? 315.618 329.058 419.126 1.00 79.51  ? 89  TYR L CD1 1 
ATOM 3531 C CD2 . TYR D 3 89  ? 315.952 331.299 419.841 1.00 79.51  ? 89  TYR L CD2 1 
ATOM 3532 C CE1 . TYR D 3 89  ? 315.203 328.711 420.392 1.00 79.51  ? 89  TYR L CE1 1 
ATOM 3533 C CE2 . TYR D 3 89  ? 315.538 330.961 421.111 1.00 79.51  ? 89  TYR L CE2 1 
ATOM 3534 C CZ  . TYR D 3 89  ? 315.166 329.665 421.380 1.00 79.51  ? 89  TYR L CZ  1 
ATOM 3535 O OH  . TYR D 3 89  ? 314.752 329.319 422.646 1.00 79.51  ? 89  TYR L OH  1 
ATOM 3536 N N   . TYR D 3 90  ? 317.878 329.120 414.798 1.00 74.45  ? 90  TYR L N   1 
ATOM 3537 C CA  . TYR D 3 90  ? 318.063 329.098 413.356 1.00 74.45  ? 90  TYR L CA  1 
ATOM 3538 C C   . TYR D 3 90  ? 316.827 328.519 412.689 1.00 74.45  ? 90  TYR L C   1 
ATOM 3539 O O   . TYR D 3 90  ? 316.098 327.720 413.282 1.00 74.45  ? 90  TYR L O   1 
ATOM 3540 C CB  . TYR D 3 90  ? 319.286 328.267 412.963 1.00 74.45  ? 90  TYR L CB  1 
ATOM 3541 C CG  . TYR D 3 90  ? 320.569 328.719 413.608 1.00 74.45  ? 90  TYR L CG  1 
ATOM 3542 C CD1 . TYR D 3 90  ? 321.164 329.915 413.247 1.00 74.45  ? 90  TYR L CD1 1 
ATOM 3543 C CD2 . TYR D 3 90  ? 321.174 327.957 414.593 1.00 74.45  ? 90  TYR L CD2 1 
ATOM 3544 C CE1 . TYR D 3 90  ? 322.335 330.333 413.838 1.00 74.45  ? 90  TYR L CE1 1 
ATOM 3545 C CE2 . TYR D 3 90  ? 322.340 328.368 415.191 1.00 74.45  ? 90  TYR L CE2 1 
ATOM 3546 C CZ  . TYR D 3 90  ? 322.917 329.557 414.810 1.00 74.45  ? 90  TYR L CZ  1 
ATOM 3547 O OH  . TYR D 3 90  ? 324.085 329.969 415.406 1.00 74.45  ? 90  TYR L OH  1 
ATOM 3548 N N   . CYS D 3 91  ? 316.596 328.928 411.444 1.00 68.64  ? 91  CYS L N   1 
ATOM 3549 C CA  . CYS D 3 91  ? 315.492 328.409 410.656 1.00 68.64  ? 91  CYS L CA  1 
ATOM 3550 C C   . CYS D 3 91  ? 315.981 328.109 409.248 1.00 68.64  ? 91  CYS L C   1 
ATOM 3551 O O   . CYS D 3 91  ? 316.942 328.713 408.768 1.00 68.64  ? 91  CYS L O   1 
ATOM 3552 C CB  . CYS D 3 91  ? 314.323 329.396 410.604 1.00 68.64  ? 91  CYS L CB  1 
ATOM 3553 S SG  . CYS D 3 91  ? 314.562 330.757 409.447 1.00 68.64  ? 91  CYS L SG  1 
ATOM 3554 N N   . GLN D 3 92  ? 315.315 327.162 408.591 1.00 61.91  ? 92  GLN L N   1 
ATOM 3555 C CA  . GLN D 3 92  ? 315.620 326.831 407.208 1.00 61.91  ? 92  GLN L CA  1 
ATOM 3556 C C   . GLN D 3 92  ? 314.353 326.390 406.496 1.00 61.91  ? 92  GLN L C   1 
ATOM 3557 O O   . GLN D 3 92  ? 313.352 326.041 407.122 1.00 61.91  ? 92  GLN L O   1 
ATOM 3558 C CB  . GLN D 3 92  ? 316.667 325.726 407.091 1.00 61.91  ? 92  GLN L CB  1 
ATOM 3559 C CG  . GLN D 3 92  ? 316.196 324.409 407.634 1.00 61.91  ? 92  GLN L CG  1 
ATOM 3560 C CD  . GLN D 3 92  ? 317.257 323.343 407.561 1.00 61.91  ? 92  GLN L CD  1 
ATOM 3561 O OE1 . GLN D 3 92  ? 317.056 322.218 408.012 1.00 61.91  ? 92  GLN L OE1 1 
ATOM 3562 N NE2 . GLN D 3 92  ? 318.397 323.689 406.989 1.00 61.91  ? 92  GLN L NE2 1 
ATOM 3563 N N   . HIS D 3 93  ? 314.415 326.406 405.171 1.00 57.52  ? 93  HIS L N   1 
ATOM 3564 C CA  . HIS D 3 93  ? 313.329 325.952 404.320 1.00 57.52  ? 93  HIS L CA  1 
ATOM 3565 C C   . HIS D 3 93  ? 313.675 324.608 403.697 1.00 57.52  ? 93  HIS L C   1 
ATOM 3566 O O   . HIS D 3 93  ? 314.826 324.170 403.705 1.00 57.52  ? 93  HIS L O   1 
ATOM 3567 C CB  . HIS D 3 93  ? 313.033 326.978 403.227 1.00 57.52  ? 93  HIS L CB  1 
ATOM 3568 C CG  . HIS D 3 93  ? 314.085 327.052 402.167 1.00 57.52  ? 93  HIS L CG  1 
ATOM 3569 N ND1 . HIS D 3 93  ? 314.031 326.307 401.011 1.00 57.52  ? 93  HIS L ND1 1 
ATOM 3570 C CD2 . HIS D 3 93  ? 315.219 327.787 402.087 1.00 57.52  ? 93  HIS L CD2 1 
ATOM 3571 C CE1 . HIS D 3 93  ? 315.085 326.577 400.264 1.00 57.52  ? 93  HIS L CE1 1 
ATOM 3572 N NE2 . HIS D 3 93  ? 315.822 327.473 400.894 1.00 57.52  ? 93  HIS L NE2 1 
ATOM 3573 N N   . PHE D 3 94  ? 312.655 323.951 403.156 1.00 53.50  ? 94  PHE L N   1 
ATOM 3574 C CA  . PHE D 3 94  ? 312.793 322.652 402.512 1.00 53.50  ? 94  PHE L CA  1 
ATOM 3575 C C   . PHE D 3 94  ? 312.032 322.626 401.198 1.00 53.50  ? 94  PHE L C   1 
ATOM 3576 O O   . PHE D 3 94  ? 311.454 321.608 400.813 1.00 53.50  ? 94  PHE L O   1 
ATOM 3577 C CB  . PHE D 3 94  ? 312.310 321.533 403.428 1.00 53.50  ? 94  PHE L CB  1 
ATOM 3578 C CG  . PHE D 3 94  ? 313.322 321.102 404.441 1.00 53.50  ? 94  PHE L CG  1 
ATOM 3579 C CD1 . PHE D 3 94  ? 314.345 320.243 404.093 1.00 53.50  ? 94  PHE L CD1 1 
ATOM 3580 C CD2 . PHE D 3 94  ? 313.247 321.549 405.744 1.00 53.50  ? 94  PHE L CD2 1 
ATOM 3581 C CE1 . PHE D 3 94  ? 315.276 319.842 405.024 1.00 53.50  ? 94  PHE L CE1 1 
ATOM 3582 C CE2 . PHE D 3 94  ? 314.174 321.150 406.678 1.00 53.50  ? 94  PHE L CE2 1 
ATOM 3583 C CZ  . PHE D 3 94  ? 315.190 320.297 406.316 1.00 53.50  ? 94  PHE L CZ  1 
ATOM 3584 N N   . TRP D 3 95  ? 312.024 323.747 400.484 1.00 50.42  ? 95  TRP L N   1 
ATOM 3585 C CA  . TRP D 3 95  ? 311.256 323.872 399.254 1.00 50.42  ? 95  TRP L CA  1 
ATOM 3586 C C   . TRP D 3 95  ? 312.063 323.569 398.000 1.00 50.42  ? 95  TRP L C   1 
ATOM 3587 O O   . TRP D 3 95  ? 311.512 323.009 397.048 1.00 50.42  ? 95  TRP L O   1 
ATOM 3588 C CB  . TRP D 3 95  ? 310.668 325.282 399.149 1.00 50.42  ? 95  TRP L CB  1 
ATOM 3589 C CG  . TRP D 3 95  ? 309.803 325.495 397.954 1.00 50.42  ? 95  TRP L CG  1 
ATOM 3590 C CD1 . TRP D 3 95  ? 310.094 326.246 396.857 1.00 50.42  ? 95  TRP L CD1 1 
ATOM 3591 C CD2 . TRP D 3 95  ? 308.496 324.956 397.735 1.00 50.42  ? 95  TRP L CD2 1 
ATOM 3592 N NE1 . TRP D 3 95  ? 309.052 326.206 395.966 1.00 50.42  ? 95  TRP L NE1 1 
ATOM 3593 C CE2 . TRP D 3 95  ? 308.059 325.418 396.482 1.00 50.42  ? 95  TRP L CE2 1 
ATOM 3594 C CE3 . TRP D 3 95  ? 307.655 324.123 398.476 1.00 50.42  ? 95  TRP L CE3 1 
ATOM 3595 C CZ2 . TRP D 3 95  ? 306.819 325.077 395.954 1.00 50.42  ? 95  TRP L CZ2 1 
ATOM 3596 C CZ3 . TRP D 3 95  ? 306.426 323.787 397.951 1.00 50.42  ? 95  TRP L CZ3 1 
ATOM 3597 C CH2 . TRP D 3 95  ? 306.020 324.260 396.701 1.00 50.42  ? 95  TRP L CH2 1 
ATOM 3598 N N   . SER D 3 96  ? 313.347 323.912 397.973 1.00 56.20  ? 96  SER L N   1 
ATOM 3599 C CA  . SER D 3 96  ? 314.201 323.681 396.817 1.00 56.20  ? 96  SER L CA  1 
ATOM 3600 C C   . SER D 3 96  ? 315.509 323.049 397.281 1.00 56.20  ? 96  SER L C   1 
ATOM 3601 O O   . SER D 3 96  ? 315.706 322.790 398.469 1.00 56.20  ? 96  SER L O   1 
ATOM 3602 C CB  . SER D 3 96  ? 314.456 324.983 396.050 1.00 56.20  ? 96  SER L CB  1 
ATOM 3603 O OG  . SER D 3 96  ? 314.857 326.017 396.930 1.00 56.20  ? 96  SER L OG  1 
ATOM 3604 N N   . THR D 3 97  ? 316.412 322.807 396.330 1.00 59.79  ? 97  THR L N   1 
ATOM 3605 C CA  . THR D 3 97  ? 317.630 322.058 396.635 1.00 59.79  ? 97  THR L CA  1 
ATOM 3606 C C   . THR D 3 97  ? 318.519 322.679 397.709 1.00 59.79  ? 97  THR L C   1 
ATOM 3607 O O   . THR D 3 97  ? 318.963 321.929 398.596 1.00 59.79  ? 97  THR L O   1 
ATOM 3608 C CB  . THR D 3 97  ? 318.446 321.836 395.353 1.00 59.79  ? 97  THR L CB  1 
ATOM 3609 O OG1 . THR D 3 97  ? 318.655 323.083 394.680 1.00 59.79  ? 97  THR L OG1 1 
ATOM 3610 C CG2 . THR D 3 97  ? 317.741 320.876 394.421 1.00 59.79  ? 97  THR L CG2 1 
ATOM 3611 N N   . PRO D 3 98  ? 318.838 323.980 397.699 1.00 59.34  ? 98  PRO L N   1 
ATOM 3612 C CA  . PRO D 3 98  ? 319.900 324.464 398.598 1.00 59.34  ? 98  PRO L CA  1 
ATOM 3613 C C   . PRO D 3 98  ? 319.621 324.271 400.081 1.00 59.34  ? 98  PRO L C   1 
ATOM 3614 O O   . PRO D 3 98  ? 320.575 324.093 400.846 1.00 59.34  ? 98  PRO L O   1 
ATOM 3615 C CB  . PRO D 3 98  ? 320.009 325.951 398.237 1.00 59.34  ? 98  PRO L CB  1 
ATOM 3616 C CG  . PRO D 3 98  ? 319.452 326.044 396.867 1.00 59.34  ? 98  PRO L CG  1 
ATOM 3617 C CD  . PRO D 3 98  ? 318.313 325.085 396.880 1.00 59.34  ? 98  PRO L CD  1 
ATOM 3618 N N   . TYR D 3 99  ? 318.362 324.304 400.516 1.00 57.06  ? 99  TYR L N   1 
ATOM 3619 C CA  . TYR D 3 99  ? 318.017 324.177 401.934 1.00 57.06  ? 99  TYR L CA  1 
ATOM 3620 C C   . TYR D 3 99  ? 318.797 325.180 402.785 1.00 57.06  ? 99  TYR L C   1 
ATOM 3621 O O   . TYR D 3 99  ? 319.379 324.838 403.816 1.00 57.06  ? 99  TYR L O   1 
ATOM 3622 C CB  . TYR D 3 99  ? 318.254 322.752 402.441 1.00 57.06  ? 99  TYR L CB  1 
ATOM 3623 C CG  . TYR D 3 99  ? 317.425 321.682 401.773 1.00 57.06  ? 99  TYR L CG  1 
ATOM 3624 C CD1 . TYR D 3 99  ? 316.128 321.932 401.366 1.00 57.06  ? 99  TYR L CD1 1 
ATOM 3625 C CD2 . TYR D 3 99  ? 317.937 320.412 401.570 1.00 57.06  ? 99  TYR L CD2 1 
ATOM 3626 C CE1 . TYR D 3 99  ? 315.370 320.951 400.764 1.00 57.06  ? 99  TYR L CE1 1 
ATOM 3627 C CE2 . TYR D 3 99  ? 317.186 319.428 400.970 1.00 57.06  ? 99  TYR L CE2 1 
ATOM 3628 C CZ  . TYR D 3 99  ? 315.904 319.703 400.566 1.00 57.06  ? 99  TYR L CZ  1 
ATOM 3629 O OH  . TYR D 3 99  ? 315.148 318.727 399.965 1.00 57.06  ? 99  TYR L OH  1 
ATOM 3630 N N   . THR D 3 100 ? 318.812 326.432 402.338 1.00 61.63  ? 100 THR L N   1 
ATOM 3631 C CA  . THR D 3 100 ? 319.625 327.448 402.991 1.00 61.63  ? 100 THR L CA  1 
ATOM 3632 C C   . THR D 3 100 ? 319.148 327.705 404.415 1.00 61.63  ? 100 THR L C   1 
ATOM 3633 O O   . THR D 3 100 ? 317.947 327.761 404.687 1.00 61.63  ? 100 THR L O   1 
ATOM 3634 C CB  . THR D 3 100 ? 319.593 328.752 402.197 1.00 61.63  ? 100 THR L CB  1 
ATOM 3635 O OG1 . THR D 3 100 ? 318.264 329.286 402.206 1.00 61.63  ? 100 THR L OG1 1 
ATOM 3636 C CG2 . THR D 3 100 ? 320.028 328.516 400.764 1.00 61.63  ? 100 THR L CG2 1 
ATOM 3637 N N   . PHE D 3 101 ? 320.104 327.864 405.325 1.00 64.83  ? 101 PHE L N   1 
ATOM 3638 C CA  . PHE D 3 101 ? 319.806 328.188 406.708 1.00 64.83  ? 101 PHE L CA  1 
ATOM 3639 C C   . PHE D 3 101 ? 319.500 329.677 406.856 1.00 64.83  ? 101 PHE L C   1 
ATOM 3640 O O   . PHE D 3 101 ? 319.615 330.463 405.914 1.00 64.83  ? 101 PHE L O   1 
ATOM 3641 C CB  . PHE D 3 101 ? 320.975 327.806 407.611 1.00 64.83  ? 101 PHE L CB  1 
ATOM 3642 C CG  . PHE D 3 101 ? 320.881 326.424 408.171 1.00 64.83  ? 101 PHE L CG  1 
ATOM 3643 C CD1 . PHE D 3 101 ? 321.455 325.356 407.514 1.00 64.83  ? 101 PHE L CD1 1 
ATOM 3644 C CD2 . PHE D 3 101 ? 320.218 326.193 409.360 1.00 64.83  ? 101 PHE L CD2 1 
ATOM 3645 C CE1 . PHE D 3 101 ? 321.370 324.085 408.031 1.00 64.83  ? 101 PHE L CE1 1 
ATOM 3646 C CE2 . PHE D 3 101 ? 320.130 324.924 409.879 1.00 64.83  ? 101 PHE L CE2 1 
ATOM 3647 C CZ  . PHE D 3 101 ? 320.708 323.869 409.216 1.00 64.83  ? 101 PHE L CZ  1 
ATOM 3648 N N   . GLY D 3 102 ? 319.105 330.061 408.070 1.00 71.66  ? 102 GLY L N   1 
ATOM 3649 C CA  . GLY D 3 102 ? 318.813 331.445 408.374 1.00 71.66  ? 102 GLY L CA  1 
ATOM 3650 C C   . GLY D 3 102 ? 319.996 332.168 408.990 1.00 71.66  ? 102 GLY L C   1 
ATOM 3651 O O   . GLY D 3 102 ? 321.057 331.599 409.241 1.00 71.66  ? 102 GLY L O   1 
ATOM 3652 N N   . GLY D 3 103 ? 319.796 333.464 409.231 1.00 78.00  ? 103 GLY L N   1 
ATOM 3653 C CA  . GLY D 3 103 ? 320.859 334.272 409.809 1.00 78.00  ? 103 GLY L CA  1 
ATOM 3654 C C   . GLY D 3 103 ? 321.191 333.886 411.237 1.00 78.00  ? 103 GLY L C   1 
ATOM 3655 O O   . GLY D 3 103 ? 322.363 333.829 411.617 1.00 78.00  ? 103 GLY L O   1 
ATOM 3656 N N   . GLY D 3 104 ? 320.178 333.618 412.042 1.00 80.42  ? 104 GLY L N   1 
ATOM 3657 C CA  . GLY D 3 104 ? 320.387 333.296 413.438 1.00 80.42  ? 104 GLY L CA  1 
ATOM 3658 C C   . GLY D 3 104 ? 320.042 334.456 414.353 1.00 80.42  ? 104 GLY L C   1 
ATOM 3659 O O   . GLY D 3 104 ? 320.145 335.631 413.985 1.00 80.42  ? 104 GLY L O   1 
ATOM 3660 N N   . THR D 3 105 ? 319.616 334.121 415.569 1.00 84.39  ? 105 THR L N   1 
ATOM 3661 C CA  . THR D 3 105 ? 319.250 335.109 416.573 1.00 84.39  ? 105 THR L CA  1 
ATOM 3662 C C   . THR D 3 105 ? 319.669 334.600 417.943 1.00 84.39  ? 105 THR L C   1 
ATOM 3663 O O   . THR D 3 105 ? 319.453 333.430 418.268 1.00 84.39  ? 105 THR L O   1 
ATOM 3664 C CB  . THR D 3 105 ? 317.743 335.394 416.551 1.00 84.39  ? 105 THR L CB  1 
ATOM 3665 O OG1 . THR D 3 105 ? 317.377 335.922 415.272 1.00 84.39  ? 105 THR L OG1 1 
ATOM 3666 C CG2 . THR D 3 105 ? 317.366 336.391 417.629 1.00 84.39  ? 105 THR L CG2 1 
ATOM 3667 N N   . LYS D 3 106 ? 320.262 335.480 418.744 1.00 89.05  ? 106 LYS L N   1 
ATOM 3668 C CA  . LYS D 3 106 ? 320.786 335.122 420.053 1.00 89.05  ? 106 LYS L CA  1 
ATOM 3669 C C   . LYS D 3 106 ? 319.953 335.767 421.151 1.00 89.05  ? 106 LYS L C   1 
ATOM 3670 O O   . LYS D 3 106 ? 319.606 336.949 421.069 1.00 89.05  ? 106 LYS L O   1 
ATOM 3671 C CB  . LYS D 3 106 ? 322.249 335.549 420.191 1.00 89.05  ? 106 LYS L CB  1 
ATOM 3672 C CG  . LYS D 3 106 ? 322.911 335.086 421.480 1.00 89.05  ? 106 LYS L CG  1 
ATOM 3673 C CD  . LYS D 3 106 ? 324.342 335.594 421.600 1.00 89.05  ? 106 LYS L CD  1 
ATOM 3674 C CE  . LYS D 3 106 ? 325.004 335.758 420.239 1.00 89.05  ? 106 LYS L CE  1 
ATOM 3675 N NZ  . LYS D 3 106 ? 326.479 335.927 420.352 1.00 89.05  ? 106 LYS L NZ  1 
ATOM 3676 N N   . LEU D 3 107 ? 319.637 334.985 422.179 1.00 91.21  ? 107 LEU L N   1 
ATOM 3677 C CA  . LEU D 3 107 ? 318.892 335.487 423.327 1.00 91.21  ? 107 LEU L CA  1 
ATOM 3678 C C   . LEU D 3 107 ? 319.833 335.893 424.456 1.00 91.21  ? 107 LEU L C   1 
ATOM 3679 O O   . LEU D 3 107 ? 319.464 336.668 425.339 1.00 91.21  ? 107 LEU L O   1 
ATOM 3680 C CB  . LEU D 3 107 ? 317.900 334.437 423.826 1.00 91.21  ? 107 LEU L CB  1 
ATOM 3681 C CG  . LEU D 3 107 ? 316.465 334.552 423.315 1.00 91.21  ? 107 LEU L CG  1 
ATOM 3682 C CD1 . LEU D 3 107 ? 315.547 333.632 424.099 1.00 91.21  ? 107 LEU L CD1 1 
ATOM 3683 C CD2 . LEU D 3 107 ? 315.986 335.985 423.408 1.00 91.21  ? 107 LEU L CD2 1 
ATOM 3684 N N   . ALA E 1 2   ? 319.635 317.200 382.529 1.00 60.58  ? 1   ALA C N   1 
ATOM 3685 C CA  . ALA E 1 2   ? 319.438 318.343 383.410 1.00 60.58  ? 1   ALA C CA  1 
ATOM 3686 C C   . ALA E 1 2   ? 319.118 319.593 382.605 1.00 60.58  ? 1   ALA C C   1 
ATOM 3687 O O   . ALA E 1 2   ? 319.300 319.620 381.388 1.00 60.58  ? 1   ALA C O   1 
ATOM 3688 C CB  . ALA E 1 2   ? 320.669 318.568 384.269 1.00 60.58  ? 1   ALA C CB  1 
ATOM 3689 N N   . LYS E 1 3   ? 318.633 320.625 383.288 1.00 56.93  ? 2   LYS C N   1 
ATOM 3690 C CA  . LYS E 1 3   ? 318.375 321.895 382.627 1.00 56.93  ? 2   LYS C CA  1 
ATOM 3691 C C   . LYS E 1 3   ? 319.688 322.522 382.178 1.00 56.93  ? 2   LYS C C   1 
ATOM 3692 O O   . LYS E 1 3   ? 320.691 322.483 382.896 1.00 56.93  ? 2   LYS C O   1 
ATOM 3693 C CB  . LYS E 1 3   ? 317.625 322.838 383.564 1.00 56.93  ? 2   LYS C CB  1 
ATOM 3694 C CG  . LYS E 1 3   ? 317.217 324.154 382.928 1.00 56.93  ? 2   LYS C CG  1 
ATOM 3695 C CD  . LYS E 1 3   ? 316.315 324.956 383.847 1.00 56.93  ? 2   LYS C CD  1 
ATOM 3696 C CE  . LYS E 1 3   ? 317.083 325.507 385.032 1.00 56.93  ? 2   LYS C CE  1 
ATOM 3697 N NZ  . LYS E 1 3   ? 318.489 325.837 384.675 1.00 56.93  ? 2   LYS C NZ  1 
ATOM 3698 N N   . LEU E 1 4   ? 319.679 323.094 380.976 1.00 53.46  ? 3   LEU C N   1 
ATOM 3699 C CA  . LEU E 1 4   ? 320.901 323.634 380.397 1.00 53.46  ? 3   LEU C CA  1 
ATOM 3700 C C   . LEU E 1 4   ? 321.417 324.814 381.211 1.00 53.46  ? 3   LEU C C   1 
ATOM 3701 O O   . LEU E 1 4   ? 320.644 325.638 381.705 1.00 53.46  ? 3   LEU C O   1 
ATOM 3702 C CB  . LEU E 1 4   ? 320.654 324.059 378.951 1.00 53.46  ? 3   LEU C CB  1 
ATOM 3703 C CG  . LEU E 1 4   ? 320.925 322.991 377.893 1.00 53.46  ? 3   LEU C CG  1 
ATOM 3704 C CD1 . LEU E 1 4   ? 320.629 323.527 376.503 1.00 53.46  ? 3   LEU C CD1 1 
ATOM 3705 C CD2 . LEU E 1 4   ? 322.357 322.505 377.991 1.00 53.46  ? 3   LEU C CD2 1 
ATOM 3706 N N   . GLU E 1 5   ? 322.738 324.882 381.353 1.00 56.94  ? 4   GLU C N   1 
ATOM 3707 C CA  . GLU E 1 5   ? 323.405 325.941 382.094 1.00 56.94  ? 4   GLU C CA  1 
ATOM 3708 C C   . GLU E 1 5   ? 324.700 326.289 381.377 1.00 56.94  ? 4   GLU C C   1 
ATOM 3709 O O   . GLU E 1 5   ? 325.162 325.553 380.504 1.00 56.94  ? 4   GLU C O   1 
ATOM 3710 C CB  . GLU E 1 5   ? 323.700 325.523 383.540 1.00 56.94  ? 4   GLU C CB  1 
ATOM 3711 C CG  . GLU E 1 5   ? 322.473 325.364 384.420 1.00 56.94  ? 4   GLU C CG  1 
ATOM 3712 C CD  . GLU E 1 5   ? 322.152 326.614 385.212 1.00 56.94  ? 4   GLU C CD  1 
ATOM 3713 O OE1 . GLU E 1 5   ? 321.397 327.467 384.702 1.00 56.94  ? 4   GLU C OE1 1 
ATOM 3714 O OE2 . GLU E 1 5   ? 322.655 326.746 386.348 1.00 56.94  ? 4   GLU C OE2 1 
ATOM 3715 N N   . THR E 1 6   ? 325.283 327.427 381.747 1.00 52.35  ? 5   THR C N   1 
ATOM 3716 C CA  . THR E 1 6   ? 326.570 327.811 381.183 1.00 52.35  ? 5   THR C CA  1 
ATOM 3717 C C   . THR E 1 6   ? 327.639 326.798 381.571 1.00 52.35  ? 5   THR C C   1 
ATOM 3718 O O   . THR E 1 6   ? 327.746 326.403 382.734 1.00 52.35  ? 5   THR C O   1 
ATOM 3719 C CB  . THR E 1 6   ? 326.976 329.204 381.662 1.00 52.35  ? 5   THR C CB  1 
ATOM 3720 O OG1 . THR E 1 6   ? 326.798 329.293 383.080 1.00 52.35  ? 5   THR C OG1 1 
ATOM 3721 C CG2 . THR E 1 6   ? 326.139 330.268 380.980 1.00 52.35  ? 5   THR C CG2 1 
ATOM 3722 N N   . VAL E 1 7   ? 328.432 326.382 380.589 1.00 49.66  ? 6   VAL C N   1 
ATOM 3723 C CA  . VAL E 1 7   ? 329.478 325.387 380.782 1.00 49.66  ? 6   VAL C CA  1 
ATOM 3724 C C   . VAL E 1 7   ? 330.815 326.066 380.534 1.00 49.66  ? 6   VAL C C   1 
ATOM 3725 O O   . VAL E 1 7   ? 331.089 326.513 379.414 1.00 49.66  ? 6   VAL C O   1 
ATOM 3726 C CB  . VAL E 1 7   ? 329.297 324.183 379.846 1.00 49.66  ? 6   VAL C CB  1 
ATOM 3727 C CG1 . VAL E 1 7   ? 330.547 323.328 379.836 1.00 49.66  ? 6   VAL C CG1 1 
ATOM 3728 C CG2 . VAL E 1 7   ? 328.090 323.366 380.261 1.00 49.66  ? 6   VAL C CG2 1 
ATOM 3729 N N   . THR E 1 8   ? 331.645 326.139 381.568 1.00 52.33  ? 7   THR C N   1 
ATOM 3730 C CA  . THR E 1 8   ? 332.976 326.723 381.467 1.00 52.33  ? 7   THR C CA  1 
ATOM 3731 C C   . THR E 1 8   ? 334.001 325.605 381.557 1.00 52.33  ? 7   THR C C   1 
ATOM 3732 O O   . THR E 1 8   ? 334.045 324.877 382.555 1.00 52.33  ? 7   THR C O   1 
ATOM 3733 C CB  . THR E 1 8   ? 333.216 327.757 382.566 1.00 52.33  ? 7   THR C CB  1 
ATOM 3734 O OG1 . THR E 1 8   ? 333.234 327.103 383.840 1.00 52.33  ? 7   THR C OG1 1 
ATOM 3735 C CG2 . THR E 1 8   ? 332.118 328.802 382.558 1.00 52.33  ? 7   THR C CG2 1 
ATOM 3736 N N   . LEU E 1 9   ? 334.819 325.472 380.521 1.00 54.49  ? 8   LEU C N   1 
ATOM 3737 C CA  . LEU E 1 9   ? 335.848 324.446 380.450 1.00 54.49  ? 8   LEU C CA  1 
ATOM 3738 C C   . LEU E 1 9   ? 337.213 325.108 380.539 1.00 54.49  ? 8   LEU C C   1 
ATOM 3739 O O   . LEU E 1 9   ? 337.485 326.077 379.822 1.00 54.49  ? 8   LEU C O   1 
ATOM 3740 C CB  . LEU E 1 9   ? 335.729 323.644 379.156 1.00 54.49  ? 8   LEU C CB  1 
ATOM 3741 C CG  . LEU E 1 9   ? 334.375 323.005 378.864 1.00 54.49  ? 8   LEU C CG  1 
ATOM 3742 C CD1 . LEU E 1 9   ? 334.268 322.636 377.399 1.00 54.49  ? 8   LEU C CD1 1 
ATOM 3743 C CD2 . LEU E 1 9   ? 334.176 321.785 379.738 1.00 54.49  ? 8   LEU C CD2 1 
ATOM 3744 N N   . GLY E 1 10  ? 338.062 324.591 381.418 1.00 59.72  ? 9   GLY C N   1 
ATOM 3745 C CA  . GLY E 1 10  ? 339.377 325.165 381.615 1.00 59.72  ? 9   GLY C CA  1 
ATOM 3746 C C   . GLY E 1 10  ? 340.492 324.258 381.150 1.00 59.72  ? 9   GLY C C   1 
ATOM 3747 O O   . GLY E 1 10  ? 340.286 323.054 380.968 1.00 59.72  ? 9   GLY C O   1 
ATOM 3748 N N   . ASN E 1 11  ? 341.680 324.832 380.950 1.00 63.11  ? 10  ASN C N   1 
ATOM 3749 C CA  . ASN E 1 11  ? 342.868 324.080 380.547 1.00 63.11  ? 10  ASN C CA  1 
ATOM 3750 C C   . ASN E 1 11  ? 342.648 323.345 379.227 1.00 63.11  ? 10  ASN C C   1 
ATOM 3751 O O   . ASN E 1 11  ? 343.046 322.191 379.061 1.00 63.11  ? 10  ASN C O   1 
ATOM 3752 C CB  . ASN E 1 11  ? 343.305 323.114 381.648 1.00 63.11  ? 10  ASN C CB  1 
ATOM 3753 C CG  . ASN E 1 11  ? 343.611 323.825 382.950 1.00 63.11  ? 10  ASN C CG  1 
ATOM 3754 O OD1 . ASN E 1 11  ? 344.250 324.877 382.959 1.00 63.11  ? 10  ASN C OD1 1 
ATOM 3755 N ND2 . ASN E 1 11  ? 343.149 323.258 384.059 1.00 63.11  ? 10  ASN C ND2 1 
ATOM 3756 N N   . ILE E 1 12  ? 342.000 324.016 378.287 1.00 61.91  ? 11  ILE C N   1 
ATOM 3757 C CA  . ILE E 1 12  ? 341.884 323.522 376.926 1.00 61.91  ? 11  ILE C CA  1 
ATOM 3758 C C   . ILE E 1 12  ? 343.101 323.992 376.137 1.00 61.91  ? 11  ILE C C   1 
ATOM 3759 O O   . ILE E 1 12  ? 343.742 324.989 376.471 1.00 61.91  ? 11  ILE C O   1 
ATOM 3760 C CB  . ILE E 1 12  ? 340.565 323.993 376.275 1.00 61.91  ? 11  ILE C CB  1 
ATOM 3761 C CG1 . ILE E 1 12  ? 339.370 323.424 377.025 1.00 61.91  ? 11  ILE C CG1 1 
ATOM 3762 C CG2 . ILE E 1 12  ? 340.457 323.576 374.823 1.00 61.91  ? 11  ILE C CG2 1 
ATOM 3763 C CD1 . ILE E 1 12  ? 338.077 324.027 376.586 1.00 61.91  ? 11  ILE C CD1 1 
ATOM 3764 N N   . GLY E 1 13  ? 343.429 323.260 375.089 1.00 64.02  ? 12  GLY C N   1 
ATOM 3765 C CA  . GLY E 1 13  ? 344.495 323.672 374.203 1.00 64.02  ? 12  GLY C CA  1 
ATOM 3766 C C   . GLY E 1 13  ? 345.736 322.822 374.371 1.00 64.02  ? 12  GLY C C   1 
ATOM 3767 O O   . GLY E 1 13  ? 346.033 322.307 375.455 1.00 64.02  ? 12  GLY C O   1 
ATOM 3768 N N   . LYS E 1 14  ? 346.478 322.668 373.275 1.00 62.89  ? 13  LYS C N   1 
ATOM 3769 C CA  . LYS E 1 14  ? 347.689 321.860 373.309 1.00 62.89  ? 13  LYS C CA  1 
ATOM 3770 C C   . LYS E 1 14  ? 348.743 322.473 374.220 1.00 62.89  ? 13  LYS C C   1 
ATOM 3771 O O   . LYS E 1 14  ? 349.604 321.757 374.743 1.00 62.89  ? 13  LYS C O   1 
ATOM 3772 C CB  . LYS E 1 14  ? 348.226 321.673 371.890 1.00 62.89  ? 13  LYS C CB  1 
ATOM 3773 C CG  . LYS E 1 14  ? 347.596 320.492 371.144 1.00 62.89  ? 13  LYS C CG  1 
ATOM 3774 C CD  . LYS E 1 14  ? 346.149 320.747 370.723 1.00 62.89  ? 13  LYS C CD  1 
ATOM 3775 C CE  . LYS E 1 14  ? 345.790 319.969 369.465 1.00 62.89  ? 13  LYS C CE  1 
ATOM 3776 N NZ  . LYS E 1 14  ? 344.344 320.064 369.130 1.00 62.89  ? 13  LYS C NZ  1 
ATOM 3777 N N   . ASP E 1 15  ? 348.696 323.791 374.423 1.00 68.16  ? 14  ASP C N   1 
ATOM 3778 C CA  . ASP E 1 15  ? 349.557 324.410 375.425 1.00 68.16  ? 14  ASP C CA  1 
ATOM 3779 C C   . ASP E 1 15  ? 349.081 324.082 376.835 1.00 68.16  ? 14  ASP C C   1 
ATOM 3780 O O   . ASP E 1 15  ? 349.898 323.830 377.728 1.00 68.16  ? 14  ASP C O   1 
ATOM 3781 C CB  . ASP E 1 15  ? 349.613 325.922 375.209 1.00 68.16  ? 14  ASP C CB  1 
ATOM 3782 C CG  . ASP E 1 15  ? 348.238 326.556 375.138 1.00 68.16  ? 14  ASP C CG  1 
ATOM 3783 O OD1 . ASP E 1 15  ? 347.581 326.677 376.191 1.00 68.16  ? 14  ASP C OD1 1 
ATOM 3784 O OD2 . ASP E 1 15  ? 347.815 326.934 374.026 1.00 68.16  ? 14  ASP C OD2 1 
ATOM 3785 N N   . GLY E 1 16  ? 347.773 324.081 377.053 1.00 66.87  ? 15  GLY C N   1 
ATOM 3786 C CA  . GLY E 1 16  ? 347.204 323.774 378.344 1.00 66.87  ? 15  GLY C CA  1 
ATOM 3787 C C   . GLY E 1 16  ? 346.791 324.965 379.179 1.00 66.87  ? 15  GLY C C   1 
ATOM 3788 O O   . GLY E 1 16  ? 346.850 324.881 380.410 1.00 66.87  ? 15  GLY C O   1 
ATOM 3789 N N   . LYS E 1 17  ? 346.379 326.069 378.557 1.00 69.10  ? 16  LYS C N   1 
ATOM 3790 C CA  . LYS E 1 17  ? 346.055 327.287 379.288 1.00 69.10  ? 16  LYS C CA  1 
ATOM 3791 C C   . LYS E 1 17  ? 344.754 327.953 378.865 1.00 69.10  ? 16  LYS C C   1 
ATOM 3792 O O   . LYS E 1 17  ? 344.216 328.747 379.644 1.00 69.10  ? 16  LYS C O   1 
ATOM 3793 C CB  . LYS E 1 17  ? 347.194 328.305 379.147 1.00 69.10  ? 16  LYS C CB  1 
ATOM 3794 C CG  . LYS E 1 17  ? 348.479 327.888 379.840 1.00 69.10  ? 16  LYS C CG  1 
ATOM 3795 C CD  . LYS E 1 17  ? 349.558 328.943 379.690 1.00 69.10  ? 16  LYS C CD  1 
ATOM 3796 C CE  . LYS E 1 17  ? 350.848 328.508 380.366 1.00 69.10  ? 16  LYS C CE  1 
ATOM 3797 N NZ  . LYS E 1 17  ? 351.923 329.526 380.220 1.00 69.10  ? 16  LYS C NZ  1 
ATOM 3798 N N   . GLN E 1 18  ? 344.232 327.666 377.676 1.00 65.81  ? 17  GLN C N   1 
ATOM 3799 C CA  . GLN E 1 18  ? 343.041 328.346 377.191 1.00 65.81  ? 17  GLN C CA  1 
ATOM 3800 C C   . GLN E 1 18  ? 341.794 327.861 377.924 1.00 65.81  ? 17  GLN C C   1 
ATOM 3801 O O   . GLN E 1 18  ? 341.757 326.768 378.494 1.00 65.81  ? 17  GLN C O   1 
ATOM 3802 C CB  . GLN E 1 18  ? 342.875 328.126 375.690 1.00 65.81  ? 17  GLN C CB  1 
ATOM 3803 C CG  . GLN E 1 18  ? 344.138 328.345 374.887 1.00 65.81  ? 17  GLN C CG  1 
ATOM 3804 C CD  . GLN E 1 18  ? 343.901 328.204 373.401 1.00 65.81  ? 17  GLN C CD  1 
ATOM 3805 O OE1 . GLN E 1 18  ? 342.878 328.647 372.877 1.00 65.81  ? 17  GLN C OE1 1 
ATOM 3806 N NE2 . GLN E 1 18  ? 344.852 327.591 372.709 1.00 65.81  ? 17  GLN C NE2 1 
ATOM 3807 N N   . THR E 1 19  ? 340.759 328.699 377.903 1.00 60.35  ? 18  THR C N   1 
ATOM 3808 C CA  . THR E 1 19  ? 339.464 328.367 378.477 1.00 60.35  ? 18  THR C CA  1 
ATOM 3809 C C   . THR E 1 19  ? 338.374 328.617 377.443 1.00 60.35  ? 18  THR C C   1 
ATOM 3810 O O   . THR E 1 19  ? 338.544 329.398 376.506 1.00 60.35  ? 18  THR C O   1 
ATOM 3811 C CB  . THR E 1 19  ? 339.162 329.184 379.741 1.00 60.35  ? 18  THR C CB  1 
ATOM 3812 O OG1 . THR E 1 19  ? 339.018 330.567 379.396 1.00 60.35  ? 18  THR C OG1 1 
ATOM 3813 C CG2 . THR E 1 19  ? 340.279 329.036 380.758 1.00 60.35  ? 18  THR C CG2 1 
ATOM 3814 N N   . LEU E 1 20  ? 337.249 327.936 377.628 1.00 52.78  ? 19  LEU C N   1 
ATOM 3815 C CA  . LEU E 1 20  ? 336.097 328.056 376.747 1.00 52.78  ? 19  LEU C CA  1 
ATOM 3816 C C   . LEU E 1 20  ? 334.836 328.177 377.588 1.00 52.78  ? 19  LEU C C   1 
ATOM 3817 O O   . LEU E 1 20  ? 334.677 327.466 378.583 1.00 52.78  ? 19  LEU C O   1 
ATOM 3818 C CB  . LEU E 1 20  ? 335.995 326.852 375.809 1.00 52.78  ? 19  LEU C CB  1 
ATOM 3819 C CG  . LEU E 1 20  ? 334.877 326.840 374.771 1.00 52.78  ? 19  LEU C CG  1 
ATOM 3820 C CD1 . LEU E 1 20  ? 335.115 327.897 373.718 1.00 52.78  ? 19  LEU C CD1 1 
ATOM 3821 C CD2 . LEU E 1 20  ? 334.770 325.471 374.136 1.00 52.78  ? 19  LEU C CD2 1 
ATOM 3822 N N   . VAL E 1 21  ? 333.945 329.082 377.191 1.00 48.83  ? 20  VAL C N   1 
ATOM 3823 C CA  . VAL E 1 21  ? 332.680 329.307 377.882 1.00 48.83  ? 20  VAL C CA  1 
ATOM 3824 C C   . VAL E 1 21  ? 331.557 329.153 376.870 1.00 48.83  ? 20  VAL C C   1 
ATOM 3825 O O   . VAL E 1 21  ? 331.514 329.882 375.873 1.00 48.83  ? 20  VAL C O   1 
ATOM 3826 C CB  . VAL E 1 21  ? 332.621 330.693 378.544 1.00 48.83  ? 20  VAL C CB  1 
ATOM 3827 C CG1 . VAL E 1 21  ? 331.288 330.886 379.239 1.00 48.83  ? 20  VAL C CG1 1 
ATOM 3828 C CG2 . VAL E 1 21  ? 333.763 330.863 379.525 1.00 48.83  ? 20  VAL C CG2 1 
ATOM 3829 N N   . LEU E 1 22  ? 330.645 328.222 377.130 1.00 45.10  ? 21  LEU C N   1 
ATOM 3830 C CA  . LEU E 1 22  ? 329.552 327.912 376.224 1.00 45.10  ? 21  LEU C CA  1 
ATOM 3831 C C   . LEU E 1 22  ? 328.225 328.315 376.852 1.00 45.10  ? 21  LEU C C   1 
ATOM 3832 O O   . LEU E 1 22  ? 328.016 328.132 378.054 1.00 45.10  ? 21  LEU C O   1 
ATOM 3833 C CB  . LEU E 1 22  ? 329.533 326.422 375.876 1.00 45.10  ? 21  LEU C CB  1 
ATOM 3834 C CG  . LEU E 1 22  ? 330.769 325.847 375.186 1.00 45.10  ? 21  LEU C CG  1 
ATOM 3835 C CD1 . LEU E 1 22  ? 330.749 324.336 375.256 1.00 45.10  ? 21  LEU C CD1 1 
ATOM 3836 C CD2 . LEU E 1 22  ? 330.852 326.302 373.745 1.00 45.10  ? 21  LEU C CD2 1 
ATOM 3837 N N   . ASN E 1 23  ? 327.332 328.867 376.032 1.00 45.18  ? 22  ASN C N   1 
ATOM 3838 C CA  . ASN E 1 23  ? 326.025 329.337 376.458 1.00 45.18  ? 22  ASN C CA  1 
ATOM 3839 C C   . ASN E 1 23  ? 324.925 328.475 375.855 1.00 45.18  ? 22  ASN C C   1 
ATOM 3840 O O   . ASN E 1 23  ? 325.051 328.026 374.712 1.00 45.18  ? 22  ASN C O   1 
ATOM 3841 C CB  . ASN E 1 23  ? 325.805 330.795 376.041 1.00 45.18  ? 22  ASN C CB  1 
ATOM 3842 C CG  . ASN E 1 23  ? 326.766 331.748 376.718 1.00 45.18  ? 22  ASN C CG  1 
ATOM 3843 O OD1 . ASN E 1 23  ? 327.683 332.272 376.087 1.00 45.18  ? 22  ASN C OD1 1 
ATOM 3844 N ND2 . ASN E 1 23  ? 326.558 331.984 378.006 1.00 45.18  ? 22  ASN C ND2 1 
ATOM 3845 N N   . PRO E 1 24  ? 323.843 328.226 376.590 1.00 43.33  ? 23  PRO C N   1 
ATOM 3846 C CA  . PRO E 1 24  ? 322.762 327.392 376.052 1.00 43.33  ? 23  PRO C CA  1 
ATOM 3847 C C   . PRO E 1 24  ? 322.114 328.027 374.831 1.00 43.33  ? 23  PRO C C   1 
ATOM 3848 O O   . PRO E 1 24  ? 322.020 329.249 374.719 1.00 43.33  ? 23  PRO C O   1 
ATOM 3849 C CB  . PRO E 1 24  ? 321.774 327.292 377.219 1.00 43.33  ? 23  PRO C CB  1 
ATOM 3850 C CG  . PRO E 1 24  ? 322.555 327.658 378.426 1.00 43.33  ? 23  PRO C CG  1 
ATOM 3851 C CD  . PRO E 1 24  ? 323.599 328.621 377.984 1.00 43.33  ? 23  PRO C CD  1 
ATOM 3852 N N   . ARG E 1 25  ? 321.662 327.177 373.910 1.00 42.23  ? 24  ARG C N   1 
ATOM 3853 C CA  . ARG E 1 25  ? 321.000 327.630 372.693 1.00 42.23  ? 24  ARG C CA  1 
ATOM 3854 C C   . ARG E 1 25  ? 319.655 326.954 372.467 1.00 42.23  ? 24  ARG C C   1 
ATOM 3855 O O   . ARG E 1 25  ? 319.122 327.020 371.355 1.00 42.23  ? 24  ARG C O   1 
ATOM 3856 C CB  . ARG E 1 25  ? 321.900 327.402 371.477 1.00 42.23  ? 24  ARG C CB  1 
ATOM 3857 C CG  . ARG E 1 25  ? 323.029 328.400 371.342 1.00 42.23  ? 24  ARG C CG  1 
ATOM 3858 C CD  . ARG E 1 25  ? 322.504 329.816 371.290 1.00 42.23  ? 24  ARG C CD  1 
ATOM 3859 N NE  . ARG E 1 25  ? 323.455 330.770 371.846 1.00 42.23  ? 24  ARG C NE  1 
ATOM 3860 C CZ  . ARG E 1 25  ? 324.159 331.631 371.127 1.00 42.23  ? 24  ARG C CZ  1 
ATOM 3861 N NH1 . ARG E 1 25  ? 324.042 331.690 369.811 1.00 42.23  ? 24  ARG C NH1 1 
ATOM 3862 N NH2 . ARG E 1 25  ? 325.001 332.455 371.743 1.00 42.23  ? 24  ARG C NH2 1 
ATOM 3863 N N   . GLY E 1 26  ? 319.103 326.292 373.474 1.00 42.15  ? 25  GLY C N   1 
ATOM 3864 C CA  . GLY E 1 26  ? 317.766 325.747 373.381 1.00 42.15  ? 25  GLY C CA  1 
ATOM 3865 C C   . GLY E 1 26  ? 317.721 324.383 372.715 1.00 42.15  ? 25  GLY C C   1 
ATOM 3866 O O   . GLY E 1 26  ? 318.658 323.943 372.054 1.00 42.15  ? 25  GLY C O   1 
ATOM 3867 N N   . VAL E 1 27  ? 316.590 323.716 372.893 1.00 41.95  ? 26  VAL C N   1 
ATOM 3868 C CA  . VAL E 1 27  ? 316.363 322.372 372.378 1.00 41.95  ? 26  VAL C CA  1 
ATOM 3869 C C   . VAL E 1 27  ? 315.558 322.457 371.089 1.00 41.95  ? 26  VAL C C   1 
ATOM 3870 O O   . VAL E 1 27  ? 314.653 323.285 370.950 1.00 41.95  ? 26  VAL C O   1 
ATOM 3871 C CB  . VAL E 1 27  ? 315.647 321.505 373.434 1.00 41.95  ? 26  VAL C CB  1 
ATOM 3872 C CG1 . VAL E 1 27  ? 315.416 320.101 372.911 1.00 41.95  ? 26  VAL C CG1 1 
ATOM 3873 C CG2 . VAL E 1 27  ? 316.448 321.469 374.719 1.00 41.95  ? 26  VAL C CG2 1 
ATOM 3874 N N   . ASN E 1 28  ? 315.890 321.591 370.133 1.00 46.95  ? 27  ASN C N   1 
ATOM 3875 C CA  . ASN E 1 28  ? 315.139 321.489 368.891 1.00 46.95  ? 27  ASN C CA  1 
ATOM 3876 C C   . ASN E 1 28  ? 313.967 320.541 369.109 1.00 46.95  ? 27  ASN C C   1 
ATOM 3877 O O   . ASN E 1 28  ? 314.193 319.350 369.361 1.00 46.95  ? 27  ASN C O   1 
ATOM 3878 C CB  . ASN E 1 28  ? 316.033 320.984 367.769 1.00 46.95  ? 27  ASN C CB  1 
ATOM 3879 C CG  . ASN E 1 28  ? 315.349 321.002 366.418 1.00 46.95  ? 27  ASN C CG  1 
ATOM 3880 O OD1 . ASN E 1 28  ? 314.220 321.467 366.284 1.00 46.95  ? 27  ASN C OD1 1 
ATOM 3881 N ND2 . ASN E 1 28  ? 316.035 320.489 365.406 1.00 46.95  ? 27  ASN C ND2 1 
ATOM 3882 N N   . PRO E 1 29  ? 312.720 321.009 369.026 1.00 49.17  ? 28  PRO C N   1 
ATOM 3883 C CA  . PRO E 1 29  ? 311.584 320.130 369.351 1.00 49.17  ? 28  PRO C CA  1 
ATOM 3884 C C   . PRO E 1 29  ? 311.462 318.909 368.456 1.00 49.17  ? 28  PRO C C   1 
ATOM 3885 O O   . PRO E 1 29  ? 311.004 317.860 368.922 1.00 49.17  ? 28  PRO C O   1 
ATOM 3886 C CB  . PRO E 1 29  ? 310.372 321.059 369.196 1.00 49.17  ? 28  PRO C CB  1 
ATOM 3887 C CG  . PRO E 1 29  ? 310.927 322.440 369.301 1.00 49.17  ? 28  PRO C CG  1 
ATOM 3888 C CD  . PRO E 1 29  ? 312.284 322.373 368.689 1.00 49.17  ? 28  PRO C CD  1 
ATOM 3889 N N   . THR E 1 30  ? 311.843 319.015 367.181 1.00 51.16  ? 29  THR C N   1 
ATOM 3890 C CA  . THR E 1 30  ? 311.627 317.910 366.253 1.00 51.16  ? 29  THR C CA  1 
ATOM 3891 C C   . THR E 1 30  ? 312.450 316.683 366.628 1.00 51.16  ? 29  THR C C   1 
ATOM 3892 O O   . THR E 1 30  ? 311.953 315.554 366.557 1.00 51.16  ? 29  THR C O   1 
ATOM 3893 C CB  . THR E 1 30  ? 311.949 318.353 364.828 1.00 51.16  ? 29  THR C CB  1 
ATOM 3894 O OG1 . THR E 1 30  ? 313.329 318.723 364.743 1.00 51.16  ? 29  THR C OG1 1 
ATOM 3895 C CG2 . THR E 1 30  ? 311.091 319.542 364.443 1.00 51.16  ? 29  THR C CG2 1 
ATOM 3896 N N   . ASN E 1 31  ? 313.708 316.878 367.027 1.00 48.78  ? 30  ASN C N   1 
ATOM 3897 C CA  . ASN E 1 31  ? 314.578 315.757 367.350 1.00 48.78  ? 30  ASN C CA  1 
ATOM 3898 C C   . ASN E 1 31  ? 315.202 315.829 368.737 1.00 48.78  ? 30  ASN C C   1 
ATOM 3899 O O   . ASN E 1 31  ? 315.995 314.947 369.080 1.00 48.78  ? 30  ASN C O   1 
ATOM 3900 C CB  . ASN E 1 31  ? 315.692 315.627 366.301 1.00 48.78  ? 30  ASN C CB  1 
ATOM 3901 C CG  . ASN E 1 31  ? 316.345 316.951 365.982 1.00 48.78  ? 30  ASN C CG  1 
ATOM 3902 O OD1 . ASN E 1 31  ? 315.913 317.998 366.457 1.00 48.78  ? 30  ASN C OD1 1 
ATOM 3903 N ND2 . ASN E 1 31  ? 317.393 316.912 365.172 1.00 48.78  ? 30  ASN C ND2 1 
ATOM 3904 N N   . GLY E 1 32  ? 314.872 316.836 369.541 1.00 45.57  ? 31  GLY C N   1 
ATOM 3905 C CA  . GLY E 1 32  ? 315.339 316.893 370.912 1.00 45.57  ? 31  GLY C CA  1 
ATOM 3906 C C   . GLY E 1 32  ? 316.842 316.959 371.070 1.00 45.57  ? 31  GLY C C   1 
ATOM 3907 O O   . GLY E 1 32  ? 317.418 316.214 371.867 1.00 45.57  ? 31  GLY C O   1 
ATOM 3908 N N   . VAL E 1 33  ? 317.493 317.840 370.319 1.00 38.99  ? 32  VAL C N   1 
ATOM 3909 C CA  . VAL E 1 33  ? 318.941 317.985 370.348 1.00 38.99  ? 32  VAL C CA  1 
ATOM 3910 C C   . VAL E 1 33  ? 319.268 319.275 371.086 1.00 38.99  ? 32  VAL C C   1 
ATOM 3911 O O   . VAL E 1 33  ? 318.965 320.371 370.603 1.00 38.99  ? 32  VAL C O   1 
ATOM 3912 C CB  . VAL E 1 33  ? 319.539 317.991 368.937 1.00 38.99  ? 32  VAL C CB  1 
ATOM 3913 C CG1 . VAL E 1 33  ? 321.047 317.988 369.009 1.00 38.99  ? 32  VAL C CG1 1 
ATOM 3914 C CG2 . VAL E 1 33  ? 319.042 316.798 368.152 1.00 38.99  ? 32  VAL C CG2 1 
ATOM 3915 N N   . ALA E 1 34  ? 319.886 319.148 372.255 1.00 34.83  ? 33  ALA C N   1 
ATOM 3916 C CA  . ALA E 1 34  ? 320.357 320.312 372.987 1.00 34.83  ? 33  ALA C CA  1 
ATOM 3917 C C   . ALA E 1 34  ? 321.517 320.961 372.246 1.00 34.83  ? 33  ALA C C   1 
ATOM 3918 O O   . ALA E 1 34  ? 322.237 320.309 371.488 1.00 34.83  ? 33  ALA C O   1 
ATOM 3919 C CB  . ALA E 1 34  ? 320.791 319.924 374.397 1.00 34.83  ? 33  ALA C CB  1 
ATOM 3920 N N   . SER E 1 35  ? 321.693 322.258 372.465 1.00 36.60  ? 34  SER C N   1 
ATOM 3921 C CA  . SER E 1 35  ? 322.706 323.014 371.747 1.00 36.60  ? 34  SER C CA  1 
ATOM 3922 C C   . SER E 1 35  ? 323.406 323.983 372.686 1.00 36.60  ? 34  SER C C   1 
ATOM 3923 O O   . SER E 1 35  ? 322.771 324.592 373.549 1.00 36.60  ? 34  SER C O   1 
ATOM 3924 C CB  . SER E 1 35  ? 322.092 323.779 370.573 1.00 36.60  ? 34  SER C CB  1 
ATOM 3925 O OG  . SER E 1 35  ? 321.217 322.949 369.831 1.00 36.60  ? 34  SER C OG  1 
ATOM 3926 N N   . LEU E 1 36  ? 324.716 324.116 372.509 1.00 38.33  ? 35  LEU C N   1 
ATOM 3927 C CA  . LEU E 1 36  ? 325.515 325.107 373.208 1.00 38.33  ? 35  LEU C CA  1 
ATOM 3928 C C   . LEU E 1 36  ? 326.411 325.805 372.198 1.00 38.33  ? 35  LEU C C   1 
ATOM 3929 O O   . LEU E 1 36  ? 326.821 325.210 371.201 1.00 38.33  ? 35  LEU C O   1 
ATOM 3930 C CB  . LEU E 1 36  ? 326.364 324.477 374.315 1.00 38.33  ? 35  LEU C CB  1 
ATOM 3931 C CG  . LEU E 1 36  ? 325.601 323.854 375.483 1.00 38.33  ? 35  LEU C CG  1 
ATOM 3932 C CD1 . LEU E 1 36  ? 325.445 322.363 375.271 1.00 38.33  ? 35  LEU C CD1 1 
ATOM 3933 C CD2 . LEU E 1 36  ? 326.294 324.138 376.800 1.00 38.33  ? 35  LEU C CD2 1 
ATOM 3934 N N   . SER E 1 37  ? 326.703 327.075 372.455 1.00 43.87  ? 36  SER C N   1 
ATOM 3935 C CA  . SER E 1 37  ? 327.520 327.862 371.544 1.00 43.87  ? 36  SER C CA  1 
ATOM 3936 C C   . SER E 1 37  ? 328.413 328.798 372.339 1.00 43.87  ? 36  SER C C   1 
ATOM 3937 O O   . SER E 1 37  ? 328.138 329.120 373.496 1.00 43.87  ? 36  SER C O   1 
ATOM 3938 C CB  . SER E 1 37  ? 326.662 328.665 370.562 1.00 43.87  ? 36  SER C CB  1 
ATOM 3939 O OG  . SER E 1 37  ? 325.963 327.809 369.679 1.00 43.87  ? 36  SER C OG  1 
ATOM 3940 N N   . GLN E 1 38  ? 329.490 329.234 371.696 1.00 47.55  ? 37  GLN C N   1 
ATOM 3941 C CA  . GLN E 1 38  ? 330.447 330.139 372.309 1.00 47.55  ? 37  GLN C CA  1 
ATOM 3942 C C   . GLN E 1 38  ? 330.075 331.579 371.994 1.00 47.55  ? 37  GLN C C   1 
ATOM 3943 O O   . GLN E 1 38  ? 329.700 331.901 370.866 1.00 47.55  ? 37  GLN C O   1 
ATOM 3944 C CB  . GLN E 1 38  ? 331.858 329.839 371.811 1.00 47.55  ? 37  GLN C CB  1 
ATOM 3945 C CG  . GLN E 1 38  ? 332.936 330.668 372.465 1.00 47.55  ? 37  GLN C CG  1 
ATOM 3946 C CD  . GLN E 1 38  ? 334.141 330.849 371.573 1.00 47.55  ? 37  GLN C CD  1 
ATOM 3947 O OE1 . GLN E 1 38  ? 334.014 330.959 370.354 1.00 47.55  ? 37  GLN C OE1 1 
ATOM 3948 N NE2 . GLN E 1 38  ? 335.323 330.880 372.174 1.00 47.55  ? 37  GLN C NE2 1 
ATOM 3949 N N   . ALA E 1 39  ? 330.185 332.446 372.997 1.00 50.71  ? 38  ALA C N   1 
ATOM 3950 C CA  . ALA E 1 39  ? 329.752 333.827 372.841 1.00 50.71  ? 38  ALA C CA  1 
ATOM 3951 C C   . ALA E 1 39  ? 330.655 334.574 371.868 1.00 50.71  ? 38  ALA C C   1 
ATOM 3952 O O   . ALA E 1 39  ? 331.884 334.502 371.959 1.00 50.71  ? 38  ALA C O   1 
ATOM 3953 C CB  . ALA E 1 39  ? 329.738 334.532 374.194 1.00 50.71  ? 38  ALA C CB  1 
ATOM 3954 N N   . GLY E 1 40  ? 330.042 335.294 370.940 1.00 54.20  ? 39  GLY C N   1 
ATOM 3955 C CA  . GLY E 1 40  ? 330.794 336.092 369.992 1.00 54.20  ? 39  GLY C CA  1 
ATOM 3956 C C   . GLY E 1 40  ? 329.868 336.648 368.932 1.00 54.20  ? 39  GLY C C   1 
ATOM 3957 O O   . GLY E 1 40  ? 328.734 336.188 368.759 1.00 54.20  ? 39  GLY C O   1 
ATOM 3958 N N   . ALA E 1 41  ? 330.373 337.656 368.227 1.00 52.22  ? 40  ALA C N   1 
ATOM 3959 C CA  . ALA E 1 41  ? 329.642 338.234 367.112 1.00 52.22  ? 40  ALA C CA  1 
ATOM 3960 C C   . ALA E 1 41  ? 329.769 337.343 365.879 1.00 52.22  ? 40  ALA C C   1 
ATOM 3961 O O   . ALA E 1 41  ? 330.565 336.401 365.840 1.00 52.22  ? 40  ALA C O   1 
ATOM 3962 C CB  . ALA E 1 41  ? 330.150 339.640 366.809 1.00 52.22  ? 40  ALA C CB  1 
ATOM 3963 N N   . VAL E 1 42  ? 328.972 337.657 364.862 1.00 49.59  ? 41  VAL C N   1 
ATOM 3964 C CA  . VAL E 1 42  ? 328.973 336.922 363.598 1.00 49.59  ? 41  VAL C CA  1 
ATOM 3965 C C   . VAL E 1 42  ? 328.667 335.457 363.885 1.00 49.59  ? 41  VAL C C   1 
ATOM 3966 O O   . VAL E 1 42  ? 329.582 334.623 363.881 1.00 49.59  ? 41  VAL C O   1 
ATOM 3967 C CB  . VAL E 1 42  ? 330.302 337.088 362.846 1.00 49.59  ? 41  VAL C CB  1 
ATOM 3968 C CG1 . VAL E 1 42  ? 330.207 336.455 361.468 1.00 49.59  ? 41  VAL C CG1 1 
ATOM 3969 C CG2 . VAL E 1 42  ? 330.671 338.555 362.746 1.00 49.59  ? 41  VAL C CG2 1 
ATOM 3970 N N   . PRO E 1 43  ? 327.412 335.108 364.185 1.00 47.01  ? 42  PRO C N   1 
ATOM 3971 C CA  . PRO E 1 43  ? 327.086 333.736 364.609 1.00 47.01  ? 42  PRO C CA  1 
ATOM 3972 C C   . PRO E 1 43  ? 327.562 332.628 363.680 1.00 47.01  ? 42  PRO C C   1 
ATOM 3973 O O   . PRO E 1 43  ? 327.489 331.451 364.040 1.00 47.01  ? 42  PRO C O   1 
ATOM 3974 C CB  . PRO E 1 43  ? 325.555 333.761 364.682 1.00 47.01  ? 42  PRO C CB  1 
ATOM 3975 C CG  . PRO E 1 43  ? 325.213 335.185 364.912 1.00 47.01  ? 42  PRO C CG  1 
ATOM 3976 C CD  . PRO E 1 43  ? 326.217 335.965 364.130 1.00 47.01  ? 42  PRO C CD  1 
ATOM 3977 N N   . ALA E 1 44  ? 328.041 332.974 362.484 1.00 47.10  ? 43  ALA C N   1 
ATOM 3978 C CA  . ALA E 1 44  ? 328.540 331.957 361.567 1.00 47.10  ? 43  ALA C CA  1 
ATOM 3979 C C   . ALA E 1 44  ? 329.935 331.469 361.937 1.00 47.10  ? 43  ALA C C   1 
ATOM 3980 O O   . ALA E 1 44  ? 330.360 330.422 361.439 1.00 47.10  ? 43  ALA C O   1 
ATOM 3981 C CB  . ALA E 1 44  ? 328.541 332.494 360.138 1.00 47.10  ? 43  ALA C CB  1 
ATOM 3982 N N   . LEU E 1 45  ? 330.654 332.194 362.795 1.00 48.21  ? 44  LEU C N   1 
ATOM 3983 C CA  . LEU E 1 45  ? 332.011 331.838 363.190 1.00 48.21  ? 44  LEU C CA  1 
ATOM 3984 C C   . LEU E 1 45  ? 332.089 331.376 364.639 1.00 48.21  ? 44  LEU C C   1 
ATOM 3985 O O   . LEU E 1 45  ? 333.045 331.711 365.345 1.00 48.21  ? 44  LEU C O   1 
ATOM 3986 C CB  . LEU E 1 45  ? 332.957 333.016 362.966 1.00 48.21  ? 44  LEU C CB  1 
ATOM 3987 C CG  . LEU E 1 45  ? 332.929 333.681 361.593 1.00 48.21  ? 44  LEU C CG  1 
ATOM 3988 C CD1 . LEU E 1 45  ? 333.817 334.906 361.591 1.00 48.21  ? 44  LEU C CD1 1 
ATOM 3989 C CD2 . LEU E 1 45  ? 333.373 332.707 360.528 1.00 48.21  ? 44  LEU C CD2 1 
ATOM 3990 N N   . GLU E 1 46  ? 331.106 330.613 365.097 1.00 48.28  ? 45  GLU C N   1 
ATOM 3991 C CA  . GLU E 1 46  ? 331.019 330.200 366.487 1.00 48.28  ? 45  GLU C CA  1 
ATOM 3992 C C   . GLU E 1 46  ? 331.278 328.705 366.625 1.00 48.28  ? 45  GLU C C   1 
ATOM 3993 O O   . GLU E 1 46  ? 331.013 327.918 365.713 1.00 48.28  ? 45  GLU C O   1 
ATOM 3994 C CB  . GLU E 1 46  ? 329.643 330.548 367.053 1.00 48.28  ? 45  GLU C CB  1 
ATOM 3995 C CG  . GLU E 1 46  ? 329.558 331.936 367.644 1.00 48.28  ? 45  GLU C CG  1 
ATOM 3996 C CD  . GLU E 1 46  ? 328.226 332.198 368.309 1.00 48.28  ? 45  GLU C CD  1 
ATOM 3997 O OE1 . GLU E 1 46  ? 327.305 331.371 368.140 1.00 48.28  ? 45  GLU C OE1 1 
ATOM 3998 O OE2 . GLU E 1 46  ? 328.096 333.233 368.993 1.00 48.28  ? 45  GLU C OE2 1 
ATOM 3999 N N   . LYS E 1 47  ? 331.802 328.322 367.786 1.00 42.13  ? 46  LYS C N   1 
ATOM 4000 C CA  . LYS E 1 47  ? 332.024 326.921 368.113 1.00 42.13  ? 46  LYS C CA  1 
ATOM 4001 C C   . LYS E 1 47  ? 330.757 326.341 368.727 1.00 42.13  ? 46  LYS C C   1 
ATOM 4002 O O   . LYS E 1 47  ? 330.185 326.929 369.649 1.00 42.13  ? 46  LYS C O   1 
ATOM 4003 C CB  . LYS E 1 47  ? 333.201 326.772 369.074 1.00 42.13  ? 46  LYS C CB  1 
ATOM 4004 C CG  . LYS E 1 47  ? 334.418 327.570 368.664 1.00 42.13  ? 46  LYS C CG  1 
ATOM 4005 C CD  . LYS E 1 47  ? 335.590 327.321 369.590 1.00 42.13  ? 46  LYS C CD  1 
ATOM 4006 C CE  . LYS E 1 47  ? 336.899 327.677 368.911 1.00 42.13  ? 46  LYS C CE  1 
ATOM 4007 N NZ  . LYS E 1 47  ? 337.911 328.188 369.871 1.00 42.13  ? 46  LYS C NZ  1 
ATOM 4008 N N   . ARG E 1 48  ? 330.329 325.189 368.223 1.00 38.53  ? 47  ARG C N   1 
ATOM 4009 C CA  . ARG E 1 48  ? 329.045 324.607 368.581 1.00 38.53  ? 47  ARG C CA  1 
ATOM 4010 C C   . ARG E 1 48  ? 329.230 323.229 369.197 1.00 38.53  ? 47  ARG C C   1 
ATOM 4011 O O   . ARG E 1 48  ? 330.138 322.486 368.821 1.00 38.53  ? 47  ARG C O   1 
ATOM 4012 C CB  . ARG E 1 48  ? 328.137 324.499 367.360 1.00 38.53  ? 47  ARG C CB  1 
ATOM 4013 C CG  . ARG E 1 48  ? 327.720 325.827 366.785 1.00 38.53  ? 47  ARG C CG  1 
ATOM 4014 C CD  . ARG E 1 48  ? 326.459 325.675 365.946 1.00 38.53  ? 47  ARG C CD  1 
ATOM 4015 N NE  . ARG E 1 48  ? 326.239 326.753 364.983 1.00 38.53  ? 47  ARG C NE  1 
ATOM 4016 C CZ  . ARG E 1 48  ? 326.279 328.055 365.245 1.00 38.53  ? 47  ARG C CZ  1 
ATOM 4017 N NH1 . ARG E 1 48  ? 326.439 328.516 366.476 1.00 38.53  ? 47  ARG C NH1 1 
ATOM 4018 N NH2 . ARG E 1 48  ? 326.126 328.919 364.246 1.00 38.53  ? 47  ARG C NH2 1 
ATOM 4019 N N   . VAL E 1 49  ? 328.365 322.904 370.156 1.00 31.00  ? 48  VAL C N   1 
ATOM 4020 C CA  . VAL E 1 49  ? 328.288 321.582 370.764 1.00 31.00  ? 48  VAL C CA  1 
ATOM 4021 C C   . VAL E 1 49  ? 326.824 321.175 370.813 1.00 31.00  ? 48  VAL C C   1 
ATOM 4022 O O   . VAL E 1 49  ? 325.962 321.984 371.170 1.00 31.00  ? 48  VAL C O   1 
ATOM 4023 C CB  . VAL E 1 49  ? 328.898 321.560 372.181 1.00 31.00  ? 48  VAL C CB  1 
ATOM 4024 C CG1 . VAL E 1 49  ? 328.983 320.144 372.696 1.00 31.00  ? 48  VAL C CG1 1 
ATOM 4025 C CG2 . VAL E 1 49  ? 330.262 322.208 372.187 1.00 31.00  ? 48  VAL C CG2 1 
ATOM 4026 N N   . THR E 1 50  ? 326.535 319.930 370.443 1.00 28.95  ? 49  THR C N   1 
ATOM 4027 C CA  . THR E 1 50  ? 325.182 319.398 370.513 1.00 28.95  ? 49  THR C CA  1 
ATOM 4028 C C   . THR E 1 50  ? 325.187 318.089 371.286 1.00 28.95  ? 49  THR C C   1 
ATOM 4029 O O   . THR E 1 50  ? 326.127 317.300 371.175 1.00 28.95  ? 49  THR C O   1 
ATOM 4030 C CB  . THR E 1 50  ? 324.583 319.163 369.124 1.00 28.95  ? 49  THR C CB  1 
ATOM 4031 O OG1 . THR E 1 50  ? 325.262 318.077 368.489 1.00 28.95  ? 49  THR C OG1 1 
ATOM 4032 C CG2 . THR E 1 50  ? 324.720 320.403 368.265 1.00 28.95  ? 49  THR C CG2 1 
ATOM 4033 N N   . VAL E 1 51  ? 324.135 317.862 372.068 1.00 28.40  ? 50  VAL C N   1 
ATOM 4034 C CA  . VAL E 1 51  ? 323.982 316.650 372.861 1.00 28.40  ? 50  VAL C CA  1 
ATOM 4035 C C   . VAL E 1 51  ? 322.595 316.081 372.612 1.00 28.40  ? 50  VAL C C   1 
ATOM 4036 O O   . VAL E 1 51  ? 321.596 316.801 372.716 1.00 28.40  ? 50  VAL C O   1 
ATOM 4037 C CB  . VAL E 1 51  ? 324.188 316.920 374.362 1.00 28.40  ? 50  VAL C CB  1 
ATOM 4038 C CG1 . VAL E 1 51  ? 323.960 315.656 375.158 1.00 28.40  ? 50  VAL C CG1 1 
ATOM 4039 C CG2 . VAL E 1 51  ? 325.575 317.471 374.616 1.00 28.40  ? 50  VAL C CG2 1 
ATOM 4040 N N   . SER E 1 52  ? 322.529 314.794 372.290 1.00 31.03  ? 51  SER C N   1 
ATOM 4041 C CA  . SER E 1 52  ? 321.270 314.113 372.031 1.00 31.03  ? 51  SER C CA  1 
ATOM 4042 C C   . SER E 1 52  ? 321.198 312.841 372.859 1.00 31.03  ? 51  SER C C   1 
ATOM 4043 O O   . SER E 1 52  ? 322.190 312.122 372.992 1.00 31.03  ? 51  SER C O   1 
ATOM 4044 C CB  . SER E 1 52  ? 321.115 313.777 370.549 1.00 31.03  ? 51  SER C CB  1 
ATOM 4045 O OG  . SER E 1 52  ? 320.018 312.911 370.337 1.00 31.03  ? 51  SER C OG  1 
ATOM 4046 N N   . VAL E 1 53  ? 320.025 312.575 373.426 1.00 34.80  ? 52  VAL C N   1 
ATOM 4047 C CA  . VAL E 1 53  ? 319.773 311.365 374.200 1.00 34.80  ? 52  VAL C CA  1 
ATOM 4048 C C   . VAL E 1 53  ? 318.405 310.828 373.809 1.00 34.80  ? 52  VAL C C   1 
ATOM 4049 O O   . VAL E 1 53  ? 317.458 311.599 373.628 1.00 34.80  ? 52  VAL C O   1 
ATOM 4050 C CB  . VAL E 1 53  ? 319.839 311.629 375.720 1.00 34.80  ? 52  VAL C CB  1 
ATOM 4051 C CG1 . VAL E 1 53  ? 319.495 310.375 376.494 1.00 34.80  ? 52  VAL C CG1 1 
ATOM 4052 C CG2 . VAL E 1 53  ? 321.209 312.132 376.120 1.00 34.80  ? 52  VAL C CG2 1 
ATOM 4053 N N   . SER E 1 54  ? 318.302 309.512 373.662 1.00 46.26  ? 53  SER C N   1 
ATOM 4054 C CA  . SER E 1 54  ? 317.010 308.901 373.389 1.00 46.26  ? 53  SER C CA  1 
ATOM 4055 C C   . SER E 1 54  ? 316.085 309.052 374.589 1.00 46.26  ? 53  SER C C   1 
ATOM 4056 O O   . SER E 1 54  ? 316.491 308.852 375.738 1.00 46.26  ? 53  SER C O   1 
ATOM 4057 C CB  . SER E 1 54  ? 317.178 307.425 373.035 1.00 46.26  ? 53  SER C CB  1 
ATOM 4058 O OG  . SER E 1 54  ? 317.887 307.277 371.820 1.00 46.26  ? 53  SER C OG  1 
ATOM 4059 N N   . GLN E 1 55  ? 314.833 309.410 374.318 1.00 57.21  ? 54  GLN C N   1 
ATOM 4060 C CA  . GLN E 1 55  ? 313.878 309.643 375.385 1.00 57.21  ? 54  GLN C CA  1 
ATOM 4061 C C   . GLN E 1 55  ? 313.530 308.329 376.083 1.00 57.21  ? 54  GLN C C   1 
ATOM 4062 O O   . GLN E 1 55  ? 313.530 307.266 375.456 1.00 57.21  ? 54  GLN C O   1 
ATOM 4063 C CB  . GLN E 1 55  ? 312.612 310.292 374.833 1.00 57.21  ? 54  GLN C CB  1 
ATOM 4064 C CG  . GLN E 1 55  ? 312.756 311.776 374.531 1.00 57.21  ? 54  GLN C CG  1 
ATOM 4065 C CD  . GLN E 1 55  ? 313.209 312.582 375.731 1.00 57.21  ? 54  GLN C CD  1 
ATOM 4066 O OE1 . GLN E 1 55  ? 312.638 312.472 376.815 1.00 57.21  ? 54  GLN C OE1 1 
ATOM 4067 N NE2 . GLN E 1 55  ? 314.248 313.385 375.547 1.00 57.21  ? 54  GLN C NE2 1 
ATOM 4068 N N   . PRO E 1 56  ? 313.236 308.375 377.382 1.00 61.79  ? 55  PRO C N   1 
ATOM 4069 C CA  . PRO E 1 56  ? 312.908 307.139 378.105 1.00 61.79  ? 55  PRO C CA  1 
ATOM 4070 C C   . PRO E 1 56  ? 311.577 306.565 377.644 1.00 61.79  ? 55  PRO C C   1 
ATOM 4071 O O   . PRO E 1 56  ? 310.574 307.275 377.550 1.00 61.79  ? 55  PRO C O   1 
ATOM 4072 C CB  . PRO E 1 56  ? 312.853 307.587 379.570 1.00 61.79  ? 55  PRO C CB  1 
ATOM 4073 C CG  . PRO E 1 56  ? 312.557 309.037 379.509 1.00 61.79  ? 55  PRO C CG  1 
ATOM 4074 C CD  . PRO E 1 56  ? 313.226 309.550 378.268 1.00 61.79  ? 55  PRO C CD  1 
ATOM 4075 N N   . SER E 1 57  ? 311.579 305.267 377.356 1.00 67.96  ? 56  SER C N   1 
ATOM 4076 C CA  . SER E 1 57  ? 310.378 304.547 376.967 1.00 67.96  ? 56  SER C CA  1 
ATOM 4077 C C   . SER E 1 57  ? 310.351 303.211 377.692 1.00 67.96  ? 56  SER C C   1 
ATOM 4078 O O   . SER E 1 57  ? 311.396 302.669 378.064 1.00 67.96  ? 56  SER C O   1 
ATOM 4079 C CB  . SER E 1 57  ? 310.312 304.325 375.451 1.00 67.96  ? 56  SER C CB  1 
ATOM 4080 O OG  . SER E 1 57  ? 309.198 303.522 375.101 1.00 67.96  ? 56  SER C OG  1 
ATOM 4081 N N   . ARG E 1 58  ? 309.143 302.688 377.898 1.00 74.69  ? 57  ARG C N   1 
ATOM 4082 C CA  . ARG E 1 58  ? 309.005 301.416 378.598 1.00 74.69  ? 57  ARG C CA  1 
ATOM 4083 C C   . ARG E 1 58  ? 309.481 300.248 377.745 1.00 74.69  ? 57  ARG C C   1 
ATOM 4084 O O   . ARG E 1 58  ? 310.019 299.272 378.280 1.00 74.69  ? 57  ARG C O   1 
ATOM 4085 C CB  . ARG E 1 58  ? 307.552 301.210 379.023 1.00 74.69  ? 57  ARG C CB  1 
ATOM 4086 C CG  . ARG E 1 58  ? 307.329 300.011 379.931 1.00 74.69  ? 57  ARG C CG  1 
ATOM 4087 C CD  . ARG E 1 58  ? 305.908 299.980 380.480 1.00 74.69  ? 57  ARG C CD  1 
ATOM 4088 N NE  . ARG E 1 58  ? 304.902 299.946 379.425 1.00 74.69  ? 57  ARG C NE  1 
ATOM 4089 C CZ  . ARG E 1 58  ? 304.169 300.987 379.054 1.00 74.69  ? 57  ARG C CZ  1 
ATOM 4090 N NH1 . ARG E 1 58  ? 304.303 302.168 379.632 1.00 74.69  ? 57  ARG C NH1 1 
ATOM 4091 N NH2 . ARG E 1 58  ? 303.278 300.838 378.078 1.00 74.69  ? 57  ARG C NH2 1 
ATOM 4092 N N   . ASN E 1 59  ? 309.302 300.326 376.426 1.00 70.19  ? 58  ASN C N   1 
ATOM 4093 C CA  . ASN E 1 59  ? 309.638 299.232 375.523 1.00 70.19  ? 58  ASN C CA  1 
ATOM 4094 C C   . ASN E 1 59  ? 310.883 299.509 374.683 1.00 70.19  ? 58  ASN C C   1 
ATOM 4095 O O   . ASN E 1 59  ? 311.099 298.844 373.666 1.00 70.19  ? 58  ASN C O   1 
ATOM 4096 C CB  . ASN E 1 59  ? 308.435 298.905 374.631 1.00 70.19  ? 58  ASN C CB  1 
ATOM 4097 C CG  . ASN E 1 59  ? 308.312 299.829 373.425 1.00 70.19  ? 58  ASN C CG  1 
ATOM 4098 O OD1 . ASN E 1 59  ? 308.835 300.944 373.413 1.00 70.19  ? 58  ASN C OD1 1 
ATOM 4099 N ND2 . ASN E 1 59  ? 307.614 299.359 372.398 1.00 70.19  ? 58  ASN C ND2 1 
ATOM 4100 N N   . ARG E 1 60  ? 311.711 300.468 375.090 1.00 59.03  ? 59  ARG C N   1 
ATOM 4101 C CA  . ARG E 1 60  ? 312.905 300.806 374.326 1.00 59.03  ? 59  ARG C CA  1 
ATOM 4102 C C   . ARG E 1 60  ? 313.974 299.736 374.510 1.00 59.03  ? 59  ARG C C   1 
ATOM 4103 O O   . ARG E 1 60  ? 314.201 299.255 375.624 1.00 59.03  ? 59  ARG C O   1 
ATOM 4104 C CB  . ARG E 1 60  ? 313.445 302.171 374.747 1.00 59.03  ? 59  ARG C CB  1 
ATOM 4105 C CG  . ARG E 1 60  ? 314.741 302.547 374.062 1.00 59.03  ? 59  ARG C CG  1 
ATOM 4106 C CD  . ARG E 1 60  ? 315.263 303.879 374.557 1.00 59.03  ? 59  ARG C CD  1 
ATOM 4107 N NE  . ARG E 1 60  ? 314.332 304.966 374.283 1.00 59.03  ? 59  ARG C NE  1 
ATOM 4108 C CZ  . ARG E 1 60  ? 314.058 305.437 373.076 1.00 59.03  ? 59  ARG C CZ  1 
ATOM 4109 N NH1 . ARG E 1 60  ? 314.633 304.943 371.992 1.00 59.03  ? 59  ARG C NH1 1 
ATOM 4110 N NH2 . ARG E 1 60  ? 313.184 306.431 372.950 1.00 59.03  ? 59  ARG C NH2 1 
ATOM 4111 N N   . LYS E 1 61  ? 314.632 299.366 373.411 1.00 58.56  ? 60  LYS C N   1 
ATOM 4112 C CA  . LYS E 1 61  ? 315.665 298.338 373.460 1.00 58.56  ? 60  LYS C CA  1 
ATOM 4113 C C   . LYS E 1 61  ? 317.032 298.932 373.778 1.00 58.56  ? 60  LYS C C   1 
ATOM 4114 O O   . LYS E 1 61  ? 317.673 298.549 374.763 1.00 58.56  ? 60  LYS C O   1 
ATOM 4115 C CB  . LYS E 1 61  ? 315.710 297.577 372.134 1.00 58.56  ? 60  LYS C CB  1 
ATOM 4116 C CG  . LYS E 1 61  ? 314.482 296.730 371.873 1.00 58.56  ? 60  LYS C CG  1 
ATOM 4117 C CD  . LYS E 1 61  ? 314.409 295.568 372.846 1.00 58.56  ? 60  LYS C CD  1 
ATOM 4118 C CE  . LYS E 1 61  ? 313.234 294.659 372.533 1.00 58.56  ? 60  LYS C CE  1 
ATOM 4119 N NZ  . LYS E 1 61  ? 313.141 293.533 373.499 1.00 58.56  ? 60  LYS C NZ  1 
ATOM 4120 N N   . ASN E 1 62  ? 317.495 299.869 372.956 1.00 54.23  ? 61  ASN C N   1 
ATOM 4121 C CA  . ASN E 1 62  ? 318.832 300.428 373.076 1.00 54.23  ? 61  ASN C CA  1 
ATOM 4122 C C   . ASN E 1 62  ? 318.765 301.931 373.292 1.00 54.23  ? 61  ASN C C   1 
ATOM 4123 O O   . ASN E 1 62  ? 317.971 302.626 372.652 1.00 54.23  ? 61  ASN C O   1 
ATOM 4124 C CB  . ASN E 1 62  ? 319.666 300.124 371.833 1.00 54.23  ? 61  ASN C CB  1 
ATOM 4125 C CG  . ASN E 1 62  ? 320.216 298.719 371.836 1.00 54.23  ? 61  ASN C CG  1 
ATOM 4126 O OD1 . ASN E 1 62  ? 319.618 297.809 372.408 1.00 54.23  ? 61  ASN C OD1 1 
ATOM 4127 N ND2 . ASN E 1 62  ? 321.366 298.532 371.200 1.00 54.23  ? 61  ASN C ND2 1 
ATOM 4128 N N   . TYR E 1 63  ? 319.613 302.424 374.186 1.00 47.54  ? 62  TYR C N   1 
ATOM 4129 C CA  . TYR E 1 63  ? 319.748 303.848 374.453 1.00 47.54  ? 62  TYR C CA  1 
ATOM 4130 C C   . TYR E 1 63  ? 320.979 304.367 373.726 1.00 47.54  ? 62  TYR C C   1 
ATOM 4131 O O   . TYR E 1 63  ? 322.053 303.767 373.816 1.00 47.54  ? 62  TYR C O   1 
ATOM 4132 C CB  . TYR E 1 63  ? 319.866 304.116 375.952 1.00 47.54  ? 62  TYR C CB  1 
ATOM 4133 C CG  . TYR E 1 63  ? 318.580 303.923 376.714 1.00 47.54  ? 62  TYR C CG  1 
ATOM 4134 C CD1 . TYR E 1 63  ? 318.004 302.669 376.837 1.00 47.54  ? 62  TYR C CD1 1 
ATOM 4135 C CD2 . TYR E 1 63  ? 317.939 304.998 377.309 1.00 47.54  ? 62  TYR C CD2 1 
ATOM 4136 C CE1 . TYR E 1 63  ? 316.828 302.492 377.531 1.00 47.54  ? 62  TYR C CE1 1 
ATOM 4137 C CE2 . TYR E 1 63  ? 316.763 304.831 378.003 1.00 47.54  ? 62  TYR C CE2 1 
ATOM 4138 C CZ  . TYR E 1 63  ? 316.212 303.576 378.111 1.00 47.54  ? 62  TYR C CZ  1 
ATOM 4139 O OH  . TYR E 1 63  ? 315.038 303.405 378.804 1.00 47.54  ? 62  TYR C OH  1 
ATOM 4140 N N   . LYS E 1 64  ? 320.820 305.474 373.009 1.00 35.11  ? 63  LYS C N   1 
ATOM 4141 C CA  . LYS E 1 64  ? 321.874 306.028 372.174 1.00 35.11  ? 63  LYS C CA  1 
ATOM 4142 C C   . LYS E 1 64  ? 322.149 307.469 372.575 1.00 35.11  ? 63  LYS C C   1 
ATOM 4143 O O   . LYS E 1 64  ? 321.235 308.297 372.592 1.00 35.11  ? 63  LYS C O   1 
ATOM 4144 C CB  . LYS E 1 64  ? 321.480 305.953 370.699 1.00 35.11  ? 63  LYS C CB  1 
ATOM 4145 C CG  . LYS E 1 64  ? 322.550 306.427 369.747 1.00 35.11  ? 63  LYS C CG  1 
ATOM 4146 C CD  . LYS E 1 64  ? 322.102 306.270 368.309 1.00 35.11  ? 63  LYS C CD  1 
ATOM 4147 C CE  . LYS E 1 64  ? 323.210 306.662 367.353 1.00 35.11  ? 63  LYS C CE  1 
ATOM 4148 N NZ  . LYS E 1 64  ? 323.501 308.120 367.425 1.00 35.11  ? 63  LYS C NZ  1 
ATOM 4149 N N   . VAL E 1 65  ? 323.408 307.764 372.885 1.00 27.48  ? 64  VAL C N   1 
ATOM 4150 C CA  . VAL E 1 65  ? 323.855 309.104 373.246 1.00 27.48  ? 64  VAL C CA  1 
ATOM 4151 C C   . VAL E 1 65  ? 324.839 309.570 372.185 1.00 27.48  ? 64  VAL C C   1 
ATOM 4152 O O   . VAL E 1 65  ? 325.789 308.852 371.861 1.00 27.48  ? 64  VAL C O   1 
ATOM 4153 C CB  . VAL E 1 65  ? 324.510 309.130 374.637 1.00 27.48  ? 64  VAL C CB  1 
ATOM 4154 C CG1 . VAL E 1 65  ? 324.980 310.528 374.970 1.00 27.48  ? 64  VAL C CG1 1 
ATOM 4155 C CG2 . VAL E 1 65  ? 323.538 308.633 375.684 1.00 27.48  ? 64  VAL C CG2 1 
ATOM 4156 N N   . GLN E 1 66  ? 324.615 310.764 371.642 1.00 28.92  ? 65  GLN C N   1 
ATOM 4157 C CA  . GLN E 1 66  ? 325.439 311.269 370.554 1.00 28.92  ? 65  GLN C CA  1 
ATOM 4158 C C   . GLN E 1 66  ? 325.843 312.710 370.827 1.00 28.92  ? 65  GLN C C   1 
ATOM 4159 O O   . GLN E 1 66  ? 325.003 313.534 371.195 1.00 28.92  ? 65  GLN C O   1 
ATOM 4160 C CB  . GLN E 1 66  ? 324.701 311.156 369.223 1.00 28.92  ? 65  GLN C CB  1 
ATOM 4161 C CG  . GLN E 1 66  ? 325.430 311.777 368.062 1.00 28.92  ? 65  GLN C CG  1 
ATOM 4162 C CD  . GLN E 1 66  ? 325.000 311.188 366.741 1.00 28.92  ? 65  GLN C CD  1 
ATOM 4163 O OE1 . GLN E 1 66  ? 323.861 311.361 366.311 1.00 28.92  ? 65  GLN C OE1 1 
ATOM 4164 N NE2 . GLN E 1 66  ? 325.913 310.482 366.086 1.00 28.92  ? 65  GLN C NE2 1 
ATOM 4165 N N   . VAL E 1 67  ? 327.127 313.009 370.641 1.00 26.06  ? 66  VAL C N   1 
ATOM 4166 C CA  . VAL E 1 67  ? 327.690 314.332 370.883 1.00 26.06  ? 66  VAL C CA  1 
ATOM 4167 C C   . VAL E 1 67  ? 328.454 314.770 369.643 1.00 26.06  ? 66  VAL C C   1 
ATOM 4168 O O   . VAL E 1 67  ? 329.180 313.974 369.040 1.00 26.06  ? 66  VAL C O   1 
ATOM 4169 C CB  . VAL E 1 67  ? 328.616 314.341 372.115 1.00 26.06  ? 66  VAL C CB  1 
ATOM 4170 C CG1 . VAL E 1 67  ? 329.064 315.750 372.437 1.00 26.06  ? 66  VAL C CG1 1 
ATOM 4171 C CG2 . VAL E 1 67  ? 327.924 313.713 373.305 1.00 26.06  ? 66  VAL C CG2 1 
ATOM 4172 N N   . LYS E 1 68  ? 328.292 316.033 369.261 1.00 26.65  ? 67  LYS C N   1 
ATOM 4173 C CA  . LYS E 1 68  ? 328.957 316.580 368.089 1.00 26.65  ? 67  LYS C CA  1 
ATOM 4174 C C   . LYS E 1 68  ? 329.676 317.872 368.448 1.00 26.65  ? 67  LYS C C   1 
ATOM 4175 O O   . LYS E 1 68  ? 329.251 318.614 369.334 1.00 26.65  ? 67  LYS C O   1 
ATOM 4176 C CB  . LYS E 1 68  ? 327.970 316.844 366.957 1.00 26.65  ? 67  LYS C CB  1 
ATOM 4177 C CG  . LYS E 1 68  ? 327.194 315.625 366.520 1.00 26.65  ? 67  LYS C CG  1 
ATOM 4178 C CD  . LYS E 1 68  ? 326.738 315.774 365.086 1.00 26.65  ? 67  LYS C CD  1 
ATOM 4179 C CE  . LYS E 1 68  ? 325.863 314.616 364.660 1.00 26.65  ? 67  LYS C CE  1 
ATOM 4180 N NZ  . LYS E 1 68  ? 326.559 313.743 363.678 1.00 26.65  ? 67  LYS C NZ  1 
ATOM 4181 N N   . ILE E 1 69  ? 330.778 318.125 367.750 1.00 28.91  ? 68  ILE C N   1 
ATOM 4182 C CA  . ILE E 1 69  ? 331.587 319.323 367.938 1.00 28.91  ? 68  ILE C CA  1 
ATOM 4183 C C   . ILE E 1 69  ? 332.026 319.812 366.567 1.00 28.91  ? 68  ILE C C   1 
ATOM 4184 O O   . ILE E 1 69  ? 332.431 319.007 365.724 1.00 28.91  ? 68  ILE C O   1 
ATOM 4185 C CB  . ILE E 1 69  ? 332.811 319.044 368.831 1.00 28.91  ? 68  ILE C CB  1 
ATOM 4186 C CG1 . ILE E 1 69  ? 332.390 318.922 370.292 1.00 28.91  ? 68  ILE C CG1 1 
ATOM 4187 C CG2 . ILE E 1 69  ? 333.860 320.122 368.670 1.00 28.91  ? 68  ILE C CG2 1 
ATOM 4188 C CD1 . ILE E 1 69  ? 333.536 318.635 371.222 1.00 28.91  ? 68  ILE C CD1 1 
ATOM 4189 N N   . GLN E 1 70  ? 331.933 321.119 366.331 1.00 34.98  ? 69  GLN C N   1 
ATOM 4190 C CA  . GLN E 1 70  ? 332.461 321.700 365.104 1.00 34.98  ? 69  GLN C CA  1 
ATOM 4191 C C   . GLN E 1 70  ? 333.064 323.064 365.397 1.00 34.98  ? 69  GLN C C   1 
ATOM 4192 O O   . GLN E 1 70  ? 332.466 323.874 366.110 1.00 34.98  ? 69  GLN C O   1 
ATOM 4193 C CB  . GLN E 1 70  ? 331.381 321.801 364.022 1.00 34.98  ? 69  GLN C CB  1 
ATOM 4194 C CG  . GLN E 1 70  ? 330.280 322.789 364.306 1.00 34.98  ? 69  GLN C CG  1 
ATOM 4195 C CD  . GLN E 1 70  ? 329.484 323.127 363.069 1.00 34.98  ? 69  GLN C CD  1 
ATOM 4196 O OE1 . GLN E 1 70  ? 329.182 322.255 362.256 1.00 34.98  ? 69  GLN C OE1 1 
ATOM 4197 N NE2 . GLN E 1 70  ? 329.145 324.400 362.913 1.00 34.98  ? 69  GLN C NE2 1 
ATOM 4198 N N   . ASN E 1 71  ? 334.260 323.298 364.871 1.00 39.19  ? 70  ASN C N   1 
ATOM 4199 C CA  . ASN E 1 71  ? 334.987 324.551 365.075 1.00 39.19  ? 70  ASN C CA  1 
ATOM 4200 C C   . ASN E 1 71  ? 335.352 325.154 363.730 1.00 39.19  ? 70  ASN C C   1 
ATOM 4201 O O   . ASN E 1 71  ? 336.234 324.615 363.034 1.00 39.19  ? 70  ASN C O   1 
ATOM 4202 C CB  . ASN E 1 71  ? 336.249 324.319 365.904 1.00 39.19  ? 70  ASN C CB  1 
ATOM 4203 C CG  . ASN E 1 71  ? 335.948 323.868 367.313 1.00 39.19  ? 70  ASN C CG  1 
ATOM 4204 O OD1 . ASN E 1 71  ? 335.075 323.036 367.537 1.00 39.19  ? 70  ASN C OD1 1 
ATOM 4205 N ND2 . ASN E 1 71  ? 336.680 324.411 368.274 1.00 39.19  ? 70  ASN C ND2 1 
ATOM 4206 N N   . PRO E 1 72  ? 334.727 326.250 363.313 1.00 45.29  ? 71  PRO C N   1 
ATOM 4207 C CA  . PRO E 1 72  ? 335.074 326.866 362.033 1.00 45.29  ? 71  PRO C CA  1 
ATOM 4208 C C   . PRO E 1 72  ? 336.185 327.895 362.164 1.00 45.29  ? 71  PRO C C   1 
ATOM 4209 O O   . PRO E 1 72  ? 336.394 328.503 363.214 1.00 45.29  ? 71  PRO C O   1 
ATOM 4210 C CB  . PRO E 1 72  ? 333.760 327.534 361.610 1.00 45.29  ? 71  PRO C CB  1 
ATOM 4211 C CG  . PRO E 1 72  ? 333.041 327.810 362.891 1.00 45.29  ? 71  PRO C CG  1 
ATOM 4212 C CD  . PRO E 1 72  ? 333.633 326.966 363.987 1.00 45.29  ? 71  PRO C CD  1 
ATOM 4213 N N   . THR E 1 73  ? 336.905 328.077 361.061 1.00 53.67  ? 72  THR C N   1 
ATOM 4214 C CA  . THR E 1 73  ? 337.991 329.044 360.973 1.00 53.67  ? 72  THR C CA  1 
ATOM 4215 C C   . THR E 1 73  ? 337.629 330.116 359.955 1.00 53.67  ? 72  THR C C   1 
ATOM 4216 O O   . THR E 1 73  ? 337.123 329.805 358.873 1.00 53.67  ? 72  THR C O   1 
ATOM 4217 C CB  . THR E 1 73  ? 339.300 328.368 360.573 1.00 53.67  ? 72  THR C CB  1 
ATOM 4218 O OG1 . THR E 1 73  ? 339.293 328.125 359.163 1.00 53.67  ? 72  THR C OG1 1 
ATOM 4219 C CG2 . THR E 1 73  ? 339.458 327.051 361.308 1.00 53.67  ? 72  THR C CG2 1 
ATOM 4220 N N   . ALA E 1 74  ? 337.901 331.369 360.300 1.00 63.86  ? 73  ALA C N   1 
ATOM 4221 C CA  . ALA E 1 74  ? 337.549 332.508 359.466 1.00 63.86  ? 73  ALA C CA  1 
ATOM 4222 C C   . ALA E 1 74  ? 338.784 333.039 358.755 1.00 63.86  ? 73  ALA C C   1 
ATOM 4223 O O   . ALA E 1 74  ? 339.835 333.222 359.378 1.00 63.86  ? 73  ALA C O   1 
ATOM 4224 C CB  . ALA E 1 74  ? 336.915 333.617 360.303 1.00 63.86  ? 73  ALA C CB  1 
ATOM 4225 N N   . CYS E 1 75  ? 338.656 333.281 357.451 1.00 75.34  ? 74  CYS C N   1 
ATOM 4226 C CA  . CYS E 1 75  ? 339.710 333.900 356.659 1.00 75.34  ? 74  CYS C CA  1 
ATOM 4227 C C   . CYS E 1 75  ? 339.123 335.082 355.908 1.00 75.34  ? 74  CYS C C   1 
ATOM 4228 O O   . CYS E 1 75  ? 338.141 334.927 355.176 1.00 75.34  ? 74  CYS C O   1 
ATOM 4229 C CB  . CYS E 1 75  ? 340.331 332.900 355.681 1.00 75.34  ? 74  CYS C CB  1 
ATOM 4230 S SG  . CYS E 1 75  ? 341.384 333.655 354.420 1.00 75.34  ? 74  CYS C SG  1 
ATOM 4231 N N   . THR E 1 76  ? 339.723 336.256 356.085 1.00 85.51  ? 75  THR C N   1 
ATOM 4232 C CA  . THR E 1 76  ? 339.295 337.445 355.363 1.00 85.51  ? 75  THR C CA  1 
ATOM 4233 C C   . THR E 1 76  ? 339.994 337.508 354.011 1.00 85.51  ? 75  THR C C   1 
ATOM 4234 O O   . THR E 1 76  ? 341.223 337.414 353.932 1.00 85.51  ? 75  THR C O   1 
ATOM 4235 C CB  . THR E 1 76  ? 339.597 338.705 356.175 1.00 85.51  ? 75  THR C CB  1 
ATOM 4236 O OG1 . THR E 1 76  ? 341.005 338.786 356.427 1.00 85.51  ? 75  THR C OG1 1 
ATOM 4237 C CG2 . THR E 1 76  ? 338.849 338.676 357.499 1.00 85.51  ? 75  THR C CG2 1 
ATOM 4238 N N   . ALA E 1 77  ? 339.210 337.676 352.950 1.00 92.91  ? 76  ALA C N   1 
ATOM 4239 C CA  . ALA E 1 77  ? 339.720 337.653 351.590 1.00 92.91  ? 76  ALA C CA  1 
ATOM 4240 C C   . ALA E 1 77  ? 339.357 338.949 350.880 1.00 92.91  ? 76  ALA C C   1 
ATOM 4241 O O   . ALA E 1 77  ? 338.392 339.631 351.238 1.00 92.91  ? 76  ALA C O   1 
ATOM 4242 C CB  . ALA E 1 77  ? 339.174 336.454 350.805 1.00 92.91  ? 76  ALA C CB  1 
ATOM 4243 N N   . ASN E 1 78  ? 340.150 339.285 349.866 1.00 99.49  ? 77  ASN C N   1 
ATOM 4244 C CA  . ASN E 1 78  ? 339.921 340.501 349.102 1.00 99.49  ? 77  ASN C CA  1 
ATOM 4245 C C   . ASN E 1 78  ? 338.616 340.413 348.321 1.00 99.49  ? 77  ASN C C   1 
ATOM 4246 O O   . ASN E 1 78  ? 338.210 339.344 347.857 1.00 99.49  ? 77  ASN C O   1 
ATOM 4247 C CB  . ASN E 1 78  ? 341.084 340.756 348.144 1.00 99.49  ? 77  ASN C CB  1 
ATOM 4248 C CG  . ASN E 1 78  ? 342.361 341.123 348.867 1.00 99.49  ? 77  ASN C CG  1 
ATOM 4249 O OD1 . ASN E 1 78  ? 342.341 341.871 349.845 1.00 99.49  ? 77  ASN C OD1 1 
ATOM 4250 N ND2 . ASN E 1 78  ? 343.482 340.597 348.390 1.00 99.49  ? 77  ASN C ND2 1 
ATOM 4251 N N   . GLY E 1 79  ? 337.957 341.560 348.175 1.00 100.28 ? 78  GLY C N   1 
ATOM 4252 C CA  . GLY E 1 79  ? 336.687 341.634 347.487 1.00 100.28 ? 78  GLY C CA  1 
ATOM 4253 C C   . GLY E 1 79  ? 335.473 341.399 348.357 1.00 100.28 ? 78  GLY C C   1 
ATOM 4254 O O   . GLY E 1 79  ? 334.345 341.533 347.864 1.00 100.28 ? 78  GLY C O   1 
ATOM 4255 N N   . SER E 1 80  ? 335.661 341.054 349.628 1.00 96.73  ? 79  SER C N   1 
ATOM 4256 C CA  . SER E 1 80  ? 334.559 340.832 350.552 1.00 96.73  ? 79  SER C CA  1 
ATOM 4257 C C   . SER E 1 80  ? 334.810 341.606 351.837 1.00 96.73  ? 79  SER C C   1 
ATOM 4258 O O   . SER E 1 80  ? 335.934 341.640 352.344 1.00 96.73  ? 79  SER C O   1 
ATOM 4259 C CB  . SER E 1 80  ? 334.383 339.344 350.866 1.00 96.73  ? 79  SER C CB  1 
ATOM 4260 O OG  . SER E 1 80  ? 333.230 339.128 351.661 1.00 96.73  ? 79  SER C OG  1 
ATOM 4261 N N   . CYS E 1 81  ? 333.753 342.237 352.351 1.00 93.89  ? 80  CYS C N   1 
ATOM 4262 C CA  . CYS E 1 81  ? 333.861 342.970 353.607 1.00 93.89  ? 80  CYS C CA  1 
ATOM 4263 C C   . CYS E 1 81  ? 333.851 342.035 354.811 1.00 93.89  ? 80  CYS C C   1 
ATOM 4264 O O   . CYS E 1 81  ? 334.531 342.298 355.810 1.00 93.89  ? 80  CYS C O   1 
ATOM 4265 C CB  . CYS E 1 81  ? 332.730 343.990 353.718 1.00 93.89  ? 80  CYS C CB  1 
ATOM 4266 S SG  . CYS E 1 81  ? 332.896 345.411 352.614 1.00 93.89  ? 80  CYS C SG  1 
ATOM 4267 N N   . ASP E 1 82  ? 333.086 340.935 354.738 1.00 82.92  ? 81  ASP C N   1 
ATOM 4268 C CA  . ASP E 1 82  ? 332.950 340.101 355.919 1.00 82.92  ? 81  ASP C CA  1 
ATOM 4269 C C   . ASP E 1 82  ? 333.809 338.847 355.809 1.00 82.92  ? 81  ASP C C   1 
ATOM 4270 O O   . ASP E 1 82  ? 334.098 338.376 354.706 1.00 82.92  ? 81  ASP C O   1 
ATOM 4271 C CB  . ASP E 1 82  ? 331.485 339.701 356.135 1.00 82.92  ? 81  ASP C CB  1 
ATOM 4272 C CG  . ASP E 1 82  ? 330.850 339.091 354.896 1.00 82.92  ? 81  ASP C CG  1 
ATOM 4273 O OD1 . ASP E 1 82  ? 331.377 338.088 354.371 1.00 82.92  ? 81  ASP C OD1 1 
ATOM 4274 O OD2 . ASP E 1 82  ? 329.812 339.617 354.445 1.00 82.92  ? 81  ASP C OD2 1 
ATOM 4275 N N   . PRO E 1 83  ? 334.242 338.294 356.939 1.00 73.86  ? 82  PRO C N   1 
ATOM 4276 C CA  . PRO E 1 83  ? 334.970 337.023 356.906 1.00 73.86  ? 82  PRO C CA  1 
ATOM 4277 C C   . PRO E 1 83  ? 334.057 335.873 356.516 1.00 73.86  ? 82  PRO C C   1 
ATOM 4278 O O   . PRO E 1 83  ? 332.834 335.938 356.641 1.00 73.86  ? 82  PRO C O   1 
ATOM 4279 C CB  . PRO E 1 83  ? 335.479 336.867 358.342 1.00 73.86  ? 82  PRO C CB  1 
ATOM 4280 C CG  . PRO E 1 83  ? 334.542 337.686 359.159 1.00 73.86  ? 82  PRO C CG  1 
ATOM 4281 C CD  . PRO E 1 83  ? 334.180 338.855 358.299 1.00 73.86  ? 82  PRO C CD  1 
ATOM 4282 N N   . SER E 1 84  ? 334.679 334.803 356.031 1.00 66.40  ? 83  SER C N   1 
ATOM 4283 C CA  . SER E 1 84  ? 333.963 333.622 355.583 1.00 66.40  ? 83  SER C CA  1 
ATOM 4284 C C   . SER E 1 84  ? 334.594 332.381 356.195 1.00 66.40  ? 83  SER C C   1 
ATOM 4285 O O   . SER E 1 84  ? 335.759 332.384 356.596 1.00 66.40  ? 83  SER C O   1 
ATOM 4286 C CB  . SER E 1 84  ? 333.961 333.514 354.054 1.00 66.40  ? 83  SER C CB  1 
ATOM 4287 O OG  . SER E 1 84  ? 335.107 332.824 353.593 1.00 66.40  ? 83  SER C OG  1 
ATOM 4288 N N   . VAL E 1 85  ? 333.804 331.314 356.268 1.00 58.39  ? 84  VAL C N   1 
ATOM 4289 C CA  . VAL E 1 85  ? 334.277 330.050 356.823 1.00 58.39  ? 84  VAL C CA  1 
ATOM 4290 C C   . VAL E 1 85  ? 335.063 329.311 355.750 1.00 58.39  ? 84  VAL C C   1 
ATOM 4291 O O   . VAL E 1 85  ? 334.548 329.044 354.660 1.00 58.39  ? 84  VAL C O   1 
ATOM 4292 C CB  . VAL E 1 85  ? 333.110 329.198 357.337 1.00 58.39  ? 84  VAL C CB  1 
ATOM 4293 C CG1 . VAL E 1 85  ? 333.557 327.765 357.540 1.00 58.39  ? 84  VAL C CG1 1 
ATOM 4294 C CG2 . VAL E 1 85  ? 332.568 329.774 358.629 1.00 58.39  ? 84  VAL C CG2 1 
ATOM 4295 N N   . THR E 1 86  ? 336.313 328.976 356.058 1.00 56.06  ? 85  THR C N   1 
ATOM 4296 C CA  . THR E 1 86  ? 337.179 328.291 355.109 1.00 56.06  ? 85  THR C CA  1 
ATOM 4297 C C   . THR E 1 86  ? 337.121 326.777 355.273 1.00 56.06  ? 85  THR C C   1 
ATOM 4298 O O   . THR E 1 86  ? 336.992 326.047 354.285 1.00 56.06  ? 85  THR C O   1 
ATOM 4299 C CB  . THR E 1 86  ? 338.621 328.775 355.269 1.00 56.06  ? 85  THR C CB  1 
ATOM 4300 O OG1 . THR E 1 86  ? 338.640 330.204 355.336 1.00 56.06  ? 85  THR C OG1 1 
ATOM 4301 C CG2 . THR E 1 86  ? 339.464 328.318 354.096 1.00 56.06  ? 85  THR C CG2 1 
ATOM 4302 N N   . ARG E 1 87  ? 337.210 326.293 356.510 1.00 47.25  ? 86  ARG C N   1 
ATOM 4303 C CA  . ARG E 1 87  ? 337.256 324.864 356.766 1.00 47.25  ? 86  ARG C CA  1 
ATOM 4304 C C   . ARG E 1 87  ? 336.625 324.578 358.119 1.00 47.25  ? 86  ARG C C   1 
ATOM 4305 O O   . ARG E 1 87  ? 336.480 325.466 358.961 1.00 47.25  ? 86  ARG C O   1 
ATOM 4306 C CB  . ARG E 1 87  ? 338.691 324.338 356.728 1.00 47.25  ? 86  ARG C CB  1 
ATOM 4307 C CG  . ARG E 1 87  ? 339.641 325.148 357.572 1.00 47.25  ? 86  ARG C CG  1 
ATOM 4308 C CD  . ARG E 1 87  ? 341.044 324.596 357.513 1.00 47.25  ? 86  ARG C CD  1 
ATOM 4309 N NE  . ARG E 1 87  ? 341.868 325.159 358.574 1.00 47.25  ? 86  ARG C NE  1 
ATOM 4310 C CZ  . ARG E 1 87  ? 342.532 326.300 358.474 1.00 47.25  ? 86  ARG C CZ  1 
ATOM 4311 N NH1 . ARG E 1 87  ? 342.501 327.023 357.369 1.00 47.25  ? 86  ARG C NH1 1 
ATOM 4312 N NH2 . ARG E 1 87  ? 343.248 326.726 359.510 1.00 47.25  ? 86  ARG C NH2 1 
ATOM 4313 N N   . GLN E 1 88  ? 336.260 323.315 358.315 1.00 40.40  ? 87  GLN C N   1 
ATOM 4314 C CA  . GLN E 1 88  ? 335.613 322.853 359.531 1.00 40.40  ? 87  GLN C CA  1 
ATOM 4315 C C   . GLN E 1 88  ? 336.426 321.727 360.151 1.00 40.40  ? 87  GLN C C   1 
ATOM 4316 O O   . GLN E 1 88  ? 337.049 320.930 359.447 1.00 40.40  ? 87  GLN C O   1 
ATOM 4317 C CB  . GLN E 1 88  ? 334.191 322.355 359.241 1.00 40.40  ? 87  GLN C CB  1 
ATOM 4318 C CG  . GLN E 1 88  ? 333.182 323.421 358.840 1.00 40.40  ? 87  GLN C CG  1 
ATOM 4319 C CD  . GLN E 1 88  ? 332.741 324.299 359.990 1.00 40.40  ? 87  GLN C CD  1 
ATOM 4320 O OE1 . GLN E 1 88  ? 333.397 324.369 361.027 1.00 40.40  ? 87  GLN C OE1 1 
ATOM 4321 N NE2 . GLN E 1 88  ? 331.616 324.977 359.811 1.00 40.40  ? 87  GLN C NE2 1 
ATOM 4322 N N   . ALA E 1 89  ? 336.413 321.669 361.479 1.00 33.96  ? 88  ALA C N   1 
ATOM 4323 C CA  . ALA E 1 89  ? 337.016 320.576 362.231 1.00 33.96  ? 88  ALA C CA  1 
ATOM 4324 C C   . ALA E 1 89  ? 335.935 319.937 363.085 1.00 33.96  ? 88  ALA C C   1 
ATOM 4325 O O   . ALA E 1 89  ? 335.430 320.566 364.019 1.00 33.96  ? 88  ALA C O   1 
ATOM 4326 C CB  . ALA E 1 89  ? 338.170 321.072 363.102 1.00 33.96  ? 88  ALA C CB  1 
ATOM 4327 N N   . TYR E 1 90  ? 335.592 318.693 362.778 1.00 30.46  ? 89  TYR C N   1 
ATOM 4328 C CA  . TYR E 1 90  ? 334.457 318.030 363.401 1.00 30.46  ? 89  TYR C CA  1 
ATOM 4329 C C   . TYR E 1 90  ? 334.900 317.043 364.473 1.00 30.46  ? 89  TYR C C   1 
ATOM 4330 O O   . TYR E 1 90  ? 336.081 316.735 364.638 1.00 30.46  ? 89  TYR C O   1 
ATOM 4331 C CB  . TYR E 1 90  ? 333.615 317.302 362.354 1.00 30.46  ? 89  TYR C CB  1 
ATOM 4332 C CG  . TYR E 1 90  ? 333.068 318.191 361.273 1.00 30.46  ? 89  TYR C CG  1 
ATOM 4333 C CD1 . TYR E 1 90  ? 332.111 319.149 361.556 1.00 30.46  ? 89  TYR C CD1 1 
ATOM 4334 C CD2 . TYR E 1 90  ? 333.496 318.061 359.964 1.00 30.46  ? 89  TYR C CD2 1 
ATOM 4335 C CE1 . TYR E 1 90  ? 331.603 319.960 360.566 1.00 30.46  ? 89  TYR C CE1 1 
ATOM 4336 C CE2 . TYR E 1 90  ? 332.995 318.865 358.969 1.00 30.46  ? 89  TYR C CE2 1 
ATOM 4337 C CZ  . TYR E 1 90  ? 332.046 319.811 359.274 1.00 30.46  ? 89  TYR C CZ  1 
ATOM 4338 O OH  . TYR E 1 90  ? 331.545 320.618 358.282 1.00 30.46  ? 89  TYR C OH  1 
ATOM 4339 N N   . ALA E 1 91  ? 333.911 316.555 365.216 1.00 27.58  ? 90  ALA C N   1 
ATOM 4340 C CA  . ALA E 1 91  ? 334.070 315.479 366.176 1.00 27.58  ? 90  ALA C CA  1 
ATOM 4341 C C   . ALA E 1 91  ? 332.722 314.795 366.317 1.00 27.58  ? 90  ALA C C   1 
ATOM 4342 O O   . ALA E 1 91  ? 331.681 315.375 366.002 1.00 27.58  ? 90  ALA C O   1 
ATOM 4343 C CB  . ALA E 1 91  ? 334.570 315.985 367.530 1.00 27.58  ? 90  ALA C CB  1 
ATOM 4344 N N   . ASP E 1 92  ? 332.741 313.553 366.789 1.00 29.77  ? 91  ASP C N   1 
ATOM 4345 C CA  . ASP E 1 92  ? 331.506 312.780 366.870 1.00 29.77  ? 91  ASP C CA  1 
ATOM 4346 C C   . ASP E 1 92  ? 331.703 311.656 367.876 1.00 29.77  ? 91  ASP C C   1 
ATOM 4347 O O   . ASP E 1 92  ? 332.547 310.782 367.664 1.00 29.77  ? 91  ASP C O   1 
ATOM 4348 C CB  . ASP E 1 92  ? 331.128 312.233 365.503 1.00 29.77  ? 91  ASP C CB  1 
ATOM 4349 C CG  . ASP E 1 92  ? 329.644 312.016 365.356 1.00 29.77  ? 91  ASP C CG  1 
ATOM 4350 O OD1 . ASP E 1 92  ? 328.970 311.811 366.384 1.00 29.77  ? 91  ASP C OD1 1 
ATOM 4351 O OD2 . ASP E 1 92  ? 329.148 312.052 364.211 1.00 29.77  ? 91  ASP C OD2 1 
ATOM 4352 N N   . VAL E 1 93  ? 330.928 311.676 368.954 1.00 27.11  ? 92  VAL C N   1 
ATOM 4353 C CA  . VAL E 1 93  ? 331.015 310.672 370.005 1.00 27.11  ? 92  VAL C CA  1 
ATOM 4354 C C   . VAL E 1 93  ? 329.658 309.998 370.124 1.00 27.11  ? 92  VAL C C   1 
ATOM 4355 O O   . VAL E 1 93  ? 328.635 310.677 370.247 1.00 27.11  ? 92  VAL C O   1 
ATOM 4356 C CB  . VAL E 1 93  ? 331.433 311.290 371.349 1.00 27.11  ? 92  VAL C CB  1 
ATOM 4357 C CG1 . VAL E 1 93  ? 331.729 310.203 372.349 1.00 27.11  ? 92  VAL C CG1 1 
ATOM 4358 C CG2 . VAL E 1 93  ? 332.631 312.193 371.168 1.00 27.11  ? 92  VAL C CG2 1 
ATOM 4359 N N   . THR E 1 94  ? 329.648 308.670 370.086 1.00 25.66  ? 93  THR C N   1 
ATOM 4360 C CA  . THR E 1 94  ? 328.415 307.902 370.184 1.00 25.66  ? 93  THR C CA  1 
ATOM 4361 C C   . THR E 1 94  ? 328.579 306.797 371.214 1.00 25.66  ? 93  THR C C   1 
ATOM 4362 O O   . THR E 1 94  ? 329.562 306.054 371.181 1.00 25.66  ? 93  THR C O   1 
ATOM 4363 C CB  . THR E 1 94  ? 328.026 307.301 368.835 1.00 25.66  ? 93  THR C CB  1 
ATOM 4364 O OG1 . THR E 1 94  ? 328.203 308.282 367.807 1.00 25.66  ? 93  THR C OG1 1 
ATOM 4365 C CG2 . THR E 1 94  ? 326.579 306.851 368.855 1.00 25.66  ? 93  THR C CG2 1 
ATOM 4366 N N   . PHE E 1 95  ? 327.616 306.694 372.121 1.00 26.53  ? 94  PHE C N   1 
ATOM 4367 C CA  . PHE E 1 95  ? 327.547 305.607 373.081 1.00 26.53  ? 94  PHE C CA  1 
ATOM 4368 C C   . PHE E 1 95  ? 326.276 304.809 372.835 1.00 26.53  ? 94  PHE C C   1 
ATOM 4369 O O   . PHE E 1 95  ? 325.255 305.357 372.416 1.00 26.53  ? 94  PHE C O   1 
ATOM 4370 C CB  . PHE E 1 95  ? 327.559 306.122 374.516 1.00 26.53  ? 94  PHE C CB  1 
ATOM 4371 C CG  . PHE E 1 95  ? 328.743 306.975 374.846 1.00 26.53  ? 94  PHE C CG  1 
ATOM 4372 C CD1 . PHE E 1 95  ? 328.696 308.343 374.682 1.00 26.53  ? 94  PHE C CD1 1 
ATOM 4373 C CD2 . PHE E 1 95  ? 329.903 306.408 375.336 1.00 26.53  ? 94  PHE C CD2 1 
ATOM 4374 C CE1 . PHE E 1 95  ? 329.781 309.126 374.994 1.00 26.53  ? 94  PHE C CE1 1 
ATOM 4375 C CE2 . PHE E 1 95  ? 330.991 307.189 375.647 1.00 26.53  ? 94  PHE C CE2 1 
ATOM 4376 C CZ  . PHE E 1 95  ? 330.930 308.549 375.475 1.00 26.53  ? 94  PHE C CZ  1 
ATOM 4377 N N   . SER E 1 96  ? 326.344 303.508 373.092 1.00 32.63  ? 95  SER C N   1 
ATOM 4378 C CA  . SER E 1 96  ? 325.207 302.624 372.868 1.00 32.63  ? 95  SER C CA  1 
ATOM 4379 C C   . SER E 1 96  ? 325.146 301.605 373.992 1.00 32.63  ? 95  SER C C   1 
ATOM 4380 O O   . SER E 1 96  ? 326.066 300.801 374.150 1.00 32.63  ? 95  SER C O   1 
ATOM 4381 C CB  . SER E 1 96  ? 325.316 301.923 371.513 1.00 32.63  ? 95  SER C CB  1 
ATOM 4382 O OG  . SER E 1 96  ? 324.503 300.768 371.476 1.00 32.63  ? 95  SER C OG  1 
ATOM 4383 N N   . PHE E 1 97  ? 324.066 301.638 374.767 1.00 37.09  ? 96  PHE C N   1 
ATOM 4384 C CA  . PHE E 1 97  ? 323.860 300.717 375.871 1.00 37.09  ? 96  PHE C CA  1 
ATOM 4385 C C   . PHE E 1 97  ? 322.556 299.963 375.663 1.00 37.09  ? 96  PHE C C   1 
ATOM 4386 O O   . PHE E 1 97  ? 321.794 300.236 374.734 1.00 37.09  ? 96  PHE C O   1 
ATOM 4387 C CB  . PHE E 1 97  ? 323.835 301.448 377.217 1.00 37.09  ? 96  PHE C CB  1 
ATOM 4388 C CG  . PHE E 1 97  ? 324.858 302.535 377.337 1.00 37.09  ? 96  PHE C CG  1 
ATOM 4389 C CD1 . PHE E 1 97  ? 326.195 302.230 377.501 1.00 37.09  ? 96  PHE C CD1 1 
ATOM 4390 C CD2 . PHE E 1 97  ? 324.480 303.864 377.298 1.00 37.09  ? 96  PHE C CD2 1 
ATOM 4391 C CE1 . PHE E 1 97  ? 327.134 303.228 377.616 1.00 37.09  ? 96  PHE C CE1 1 
ATOM 4392 C CE2 . PHE E 1 97  ? 325.417 304.864 377.413 1.00 37.09  ? 96  PHE C CE2 1 
ATOM 4393 C CZ  . PHE E 1 97  ? 326.745 304.545 377.574 1.00 37.09  ? 96  PHE C CZ  1 
ATOM 4394 N N   . THR E 1 98  ? 322.306 299.001 376.543 1.00 46.09  ? 97  THR C N   1 
ATOM 4395 C CA  . THR E 1 98  ? 321.081 298.219 376.535 1.00 46.09  ? 97  THR C CA  1 
ATOM 4396 C C   . THR E 1 98  ? 320.232 298.566 377.750 1.00 46.09  ? 97  THR C C   1 
ATOM 4397 O O   . THR E 1 98  ? 320.678 299.237 378.683 1.00 46.09  ? 97  THR C O   1 
ATOM 4398 C CB  . THR E 1 98  ? 321.387 296.719 376.512 1.00 46.09  ? 97  THR C CB  1 
ATOM 4399 O OG1 . THR E 1 98  ? 322.406 296.426 377.474 1.00 46.09  ? 97  THR C OG1 1 
ATOM 4400 C CG2 . THR E 1 98  ? 321.862 296.298 375.138 1.00 46.09  ? 97  THR C CG2 1 
ATOM 4401 N N   . GLN E 1 99  ? 318.987 298.090 377.725 1.00 48.46  ? 98  GLN C N   1 
ATOM 4402 C CA  . GLN E 1 99  ? 318.043 298.397 378.792 1.00 48.46  ? 98  GLN C CA  1 
ATOM 4403 C C   . GLN E 1 99  ? 318.436 297.776 380.124 1.00 48.46  ? 98  GLN C C   1 
ATOM 4404 O O   . GLN E 1 99  ? 318.007 298.268 381.170 1.00 48.46  ? 98  GLN C O   1 
ATOM 4405 C CB  . GLN E 1 99  ? 316.646 297.925 378.399 1.00 48.46  ? 98  GLN C CB  1 
ATOM 4406 C CG  . GLN E 1 99  ? 316.585 296.456 378.034 1.00 48.46  ? 98  GLN C CG  1 
ATOM 4407 C CD  . GLN E 1 99  ? 315.193 296.002 377.657 1.00 48.46  ? 98  GLN C CD  1 
ATOM 4408 O OE1 . GLN E 1 99  ? 314.257 296.799 377.622 1.00 48.46  ? 98  GLN C OE1 1 
ATOM 4409 N NE2 . GLN E 1 99  ? 315.047 294.714 377.374 1.00 48.46  ? 98  GLN C NE2 1 
ATOM 4410 N N   . TYR E 1 100 ? 319.236 296.713 380.116 1.00 47.56  ? 99  TYR C N   1 
ATOM 4411 C CA  . TYR E 1 100 ? 319.605 296.014 381.339 1.00 47.56  ? 99  TYR C CA  1 
ATOM 4412 C C   . TYR E 1 100 ? 320.937 296.465 381.916 1.00 47.56  ? 99  TYR C C   1 
ATOM 4413 O O   . TYR E 1 100 ? 321.356 295.932 382.946 1.00 47.56  ? 99  TYR C O   1 
ATOM 4414 C CB  . TYR E 1 100 ? 319.644 294.507 381.088 1.00 47.56  ? 99  TYR C CB  1 
ATOM 4415 C CG  . TYR E 1 100 ? 318.275 293.882 381.022 1.00 47.56  ? 99  TYR C CG  1 
ATOM 4416 C CD1 . TYR E 1 100 ? 317.489 293.774 382.159 1.00 47.56  ? 99  TYR C CD1 1 
ATOM 4417 C CD2 . TYR E 1 100 ? 317.761 293.415 379.824 1.00 47.56  ? 99  TYR C CD2 1 
ATOM 4418 C CE1 . TYR E 1 100 ? 316.237 293.212 382.106 1.00 47.56  ? 99  TYR C CE1 1 
ATOM 4419 C CE2 . TYR E 1 100 ? 316.510 292.850 379.762 1.00 47.56  ? 99  TYR C CE2 1 
ATOM 4420 C CZ  . TYR E 1 100 ? 315.751 292.752 380.906 1.00 47.56  ? 99  TYR C CZ  1 
ATOM 4421 O OH  . TYR E 1 100 ? 314.499 292.187 380.851 1.00 47.56  ? 99  TYR C OH  1 
ATOM 4422 N N   . SER E 1 101 ? 321.605 297.431 381.295 1.00 46.06  ? 100 SER C N   1 
ATOM 4423 C CA  . SER E 1 101 ? 322.896 297.883 381.788 1.00 46.06  ? 100 SER C CA  1 
ATOM 4424 C C   . SER E 1 101 ? 322.735 298.663 383.086 1.00 46.06  ? 100 SER C C   1 
ATOM 4425 O O   . SER E 1 101 ? 321.671 299.209 383.383 1.00 46.06  ? 100 SER C O   1 
ATOM 4426 C CB  . SER E 1 101 ? 323.587 298.749 380.743 1.00 46.06  ? 100 SER C CB  1 
ATOM 4427 O OG  . SER E 1 101 ? 322.829 299.915 380.484 1.00 46.06  ? 100 SER C OG  1 
ATOM 4428 N N   . THR E 1 102 ? 323.808 298.710 383.865 1.00 48.32  ? 101 THR C N   1 
ATOM 4429 C CA  . THR E 1 102 ? 323.819 299.438 385.122 1.00 48.32  ? 101 THR C CA  1 
ATOM 4430 C C   . THR E 1 102 ? 324.697 300.680 385.013 1.00 48.32  ? 101 THR C C   1 
ATOM 4431 O O   . THR E 1 102 ? 325.408 300.889 384.030 1.00 48.32  ? 101 THR C O   1 
ATOM 4432 C CB  . THR E 1 102 ? 324.296 298.537 386.266 1.00 48.32  ? 101 THR C CB  1 
ATOM 4433 O OG1 . THR E 1 102 ? 324.131 299.221 387.514 1.00 48.32  ? 101 THR C OG1 1 
ATOM 4434 C CG2 . THR E 1 102 ? 325.752 298.176 386.090 1.00 48.32  ? 101 THR C CG2 1 
ATOM 4435 N N   . ASP E 1 103 ? 324.629 301.515 386.051 1.00 51.62  ? 102 ASP C N   1 
ATOM 4436 C CA  . ASP E 1 103 ? 325.294 302.814 386.017 1.00 51.62  ? 102 ASP C CA  1 
ATOM 4437 C C   . ASP E 1 103 ? 326.809 302.664 385.949 1.00 51.62  ? 102 ASP C C   1 
ATOM 4438 O O   . ASP E 1 103 ? 327.485 303.430 385.249 1.00 51.62  ? 102 ASP C O   1 
ATOM 4439 C CB  . ASP E 1 103 ? 324.887 303.627 387.246 1.00 51.62  ? 102 ASP C CB  1 
ATOM 4440 C CG  . ASP E 1 103 ? 325.360 305.068 387.188 1.00 51.62  ? 102 ASP C CG  1 
ATOM 4441 O OD1 . ASP E 1 103 ? 326.034 305.452 386.211 1.00 51.62  ? 102 ASP C OD1 1 
ATOM 4442 O OD2 . ASP E 1 103 ? 325.053 305.827 388.132 1.00 51.62  ? 102 ASP C OD2 1 
ATOM 4443 N N   . GLU E 1 104 ? 327.359 301.687 386.672 1.00 50.53  ? 103 GLU C N   1 
ATOM 4444 C CA  . GLU E 1 104 ? 328.809 301.559 386.761 1.00 50.53  ? 103 GLU C CA  1 
ATOM 4445 C C   . GLU E 1 104 ? 329.430 301.273 385.401 1.00 50.53  ? 103 GLU C C   1 
ATOM 4446 O O   . GLU E 1 104 ? 330.514 301.777 385.094 1.00 50.53  ? 103 GLU C O   1 
ATOM 4447 C CB  . GLU E 1 104 ? 329.182 300.472 387.763 1.00 50.53  ? 103 GLU C CB  1 
ATOM 4448 C CG  . GLU E 1 104 ? 329.468 301.004 389.155 1.00 50.53  ? 103 GLU C CG  1 
ATOM 4449 C CD  . GLU E 1 104 ? 330.195 300.002 390.029 1.00 50.53  ? 103 GLU C CD  1 
ATOM 4450 O OE1 . GLU E 1 104 ? 330.135 298.792 389.730 1.00 50.53  ? 103 GLU C OE1 1 
ATOM 4451 O OE2 . GLU E 1 104 ? 330.830 300.427 391.017 1.00 50.53  ? 103 GLU C OE2 1 
ATOM 4452 N N   . GLU E 1 105 ? 328.762 300.472 384.571 1.00 48.90  ? 104 GLU C N   1 
ATOM 4453 C CA  . GLU E 1 105 ? 329.291 300.184 383.241 1.00 48.90  ? 104 GLU C CA  1 
ATOM 4454 C C   . GLU E 1 105 ? 329.408 301.454 382.408 1.00 48.90  ? 104 GLU C C   1 
ATOM 4455 O O   . GLU E 1 105 ? 330.441 301.708 381.774 1.00 48.90  ? 104 GLU C O   1 
ATOM 4456 C CB  . GLU E 1 105 ? 328.401 299.164 382.536 1.00 48.90  ? 104 GLU C CB  1 
ATOM 4457 C CG  . GLU E 1 105 ? 328.034 297.971 383.390 1.00 48.90  ? 104 GLU C CG  1 
ATOM 4458 C CD  . GLU E 1 105 ? 327.031 297.058 382.715 1.00 48.90  ? 104 GLU C CD  1 
ATOM 4459 O OE1 . GLU E 1 105 ? 326.678 297.324 381.548 1.00 48.90  ? 104 GLU C OE1 1 
ATOM 4460 O OE2 . GLU E 1 105 ? 326.596 296.076 383.351 1.00 48.90  ? 104 GLU C OE2 1 
ATOM 4461 N N   . ARG E 1 106 ? 328.353 302.267 382.401 1.00 43.42  ? 105 ARG C N   1 
ATOM 4462 C CA  . ARG E 1 106 ? 328.364 303.492 381.612 1.00 43.42  ? 105 ARG C CA  1 
ATOM 4463 C C   . ARG E 1 106 ? 329.405 304.476 382.131 1.00 43.42  ? 105 ARG C C   1 
ATOM 4464 O O   . ARG E 1 106 ? 330.133 305.096 381.343 1.00 43.42  ? 105 ARG C O   1 
ATOM 4465 C CB  . ARG E 1 106 ? 326.969 304.110 381.619 1.00 43.42  ? 105 ARG C CB  1 
ATOM 4466 C CG  . ARG E 1 106 ? 325.869 303.094 381.352 1.00 43.42  ? 105 ARG C CG  1 
ATOM 4467 C CD  . ARG E 1 106 ? 324.521 303.754 381.149 1.00 43.42  ? 105 ARG C CD  1 
ATOM 4468 N NE  . ARG E 1 106 ? 323.971 304.273 382.393 1.00 43.42  ? 105 ARG C NE  1 
ATOM 4469 C CZ  . ARG E 1 106 ? 322.839 303.855 382.941 1.00 43.42  ? 105 ARG C CZ  1 
ATOM 4470 N NH1 . ARG E 1 106 ? 322.103 302.916 382.371 1.00 43.42  ? 105 ARG C NH1 1 
ATOM 4471 N NH2 . ARG E 1 106 ? 322.433 304.393 384.086 1.00 43.42  ? 105 ARG C NH2 1 
ATOM 4472 N N   . ALA E 1 107 ? 329.496 304.626 383.453 1.00 43.06  ? 106 ALA C N   1 
ATOM 4473 C CA  . ALA E 1 107 ? 330.503 305.516 384.019 1.00 43.06  ? 106 ALA C CA  1 
ATOM 4474 C C   . ALA E 1 107 ? 331.909 305.037 383.686 1.00 43.06  ? 106 ALA C C   1 
ATOM 4475 O O   . ALA E 1 107 ? 332.794 305.845 383.378 1.00 43.06  ? 106 ALA C O   1 
ATOM 4476 C CB  . ALA E 1 107 ? 330.316 305.629 385.530 1.00 43.06  ? 106 ALA C CB  1 
ATOM 4477 N N   . PHE E 1 108 ? 332.134 303.722 383.742 1.00 41.06  ? 107 PHE C N   1 
ATOM 4478 C CA  . PHE E 1 108 ? 333.440 303.176 383.402 1.00 41.06  ? 107 PHE C CA  1 
ATOM 4479 C C   . PHE E 1 108 ? 333.794 303.459 381.952 1.00 41.06  ? 107 PHE C C   1 
ATOM 4480 O O   . PHE E 1 108 ? 334.919 303.867 381.653 1.00 41.06  ? 107 PHE C O   1 
ATOM 4481 C CB  . PHE E 1 108 ? 333.463 301.674 383.677 1.00 41.06  ? 107 PHE C CB  1 
ATOM 4482 C CG  . PHE E 1 108 ? 334.789 301.031 383.410 1.00 41.06  ? 107 PHE C CG  1 
ATOM 4483 C CD1 . PHE E 1 108 ? 335.807 301.103 384.340 1.00 41.06  ? 107 PHE C CD1 1 
ATOM 4484 C CD2 . PHE E 1 108 ? 335.017 300.353 382.228 1.00 41.06  ? 107 PHE C CD2 1 
ATOM 4485 C CE1 . PHE E 1 108 ? 337.025 300.512 384.096 1.00 41.06  ? 107 PHE C CE1 1 
ATOM 4486 C CE2 . PHE E 1 108 ? 336.235 299.761 381.980 1.00 41.06  ? 107 PHE C CE2 1 
ATOM 4487 C CZ  . PHE E 1 108 ? 337.238 299.842 382.914 1.00 41.06  ? 107 PHE C CZ  1 
ATOM 4488 N N   . VAL E 1 109 ? 332.844 303.262 381.036 1.00 38.36  ? 108 VAL C N   1 
ATOM 4489 C CA  . VAL E 1 109 ? 333.118 303.524 379.624 1.00 38.36  ? 108 VAL C CA  1 
ATOM 4490 C C   . VAL E 1 109 ? 333.460 304.993 379.410 1.00 38.36  ? 108 VAL C C   1 
ATOM 4491 O O   . VAL E 1 109 ? 334.423 305.331 378.710 1.00 38.36  ? 108 VAL C O   1 
ATOM 4492 C CB  . VAL E 1 109 ? 331.924 303.096 378.752 1.00 38.36  ? 108 VAL C CB  1 
ATOM 4493 C CG1 . VAL E 1 109 ? 332.149 303.519 377.320 1.00 38.36  ? 108 VAL C CG1 1 
ATOM 4494 C CG2 . VAL E 1 109 ? 331.720 301.603 378.831 1.00 38.36  ? 108 VAL C CG2 1 
ATOM 4495 N N   . ARG E 1 110 ? 332.676 305.890 380.014 1.00 36.96  ? 109 ARG C N   1 
ATOM 4496 C CA  . ARG E 1 110 ? 332.905 307.317 379.806 1.00 36.96  ? 109 ARG C CA  1 
ATOM 4497 C C   . ARG E 1 110 ? 334.257 307.753 380.361 1.00 36.96  ? 109 ARG C C   1 
ATOM 4498 O O   . ARG E 1 110 ? 335.019 308.463 379.691 1.00 36.96  ? 109 ARG C O   1 
ATOM 4499 C CB  . ARG E 1 110 ? 331.776 308.123 380.442 1.00 36.96  ? 109 ARG C CB  1 
ATOM 4500 C CG  . ARG E 1 110 ? 332.074 309.598 380.573 1.00 36.96  ? 109 ARG C CG  1 
ATOM 4501 C CD  . ARG E 1 110 ? 331.031 310.292 381.419 1.00 36.96  ? 109 ARG C CD  1 
ATOM 4502 N NE  . ARG E 1 110 ? 331.120 309.897 382.817 1.00 36.96  ? 109 ARG C NE  1 
ATOM 4503 C CZ  . ARG E 1 110 ? 331.928 310.461 383.703 1.00 36.96  ? 109 ARG C CZ  1 
ATOM 4504 N NH1 . ARG E 1 110 ? 332.735 311.451 383.369 1.00 36.96  ? 109 ARG C NH1 1 
ATOM 4505 N NH2 . ARG E 1 110 ? 331.923 310.021 384.957 1.00 36.96  ? 109 ARG C NH2 1 
ATOM 4506 N N   . THR E 1 111 ? 334.577 307.334 381.588 1.00 37.90  ? 110 THR C N   1 
ATOM 4507 C CA  . THR E 1 111 ? 335.858 307.710 382.177 1.00 37.90  ? 110 THR C CA  1 
ATOM 4508 C C   . THR E 1 111 ? 337.023 307.094 381.413 1.00 37.90  ? 110 THR C C   1 
ATOM 4509 O O   . THR E 1 111 ? 338.078 307.722 381.271 1.00 37.90  ? 110 THR C O   1 
ATOM 4510 C CB  . THR E 1 111 ? 335.905 307.301 383.646 1.00 37.90  ? 110 THR C CB  1 
ATOM 4511 O OG1 . THR E 1 111 ? 335.427 305.958 383.784 1.00 37.90  ? 110 THR C OG1 1 
ATOM 4512 C CG2 . THR E 1 111 ? 335.041 308.226 384.477 1.00 37.90  ? 110 THR C CG2 1 
ATOM 4513 N N   . GLU E 1 112 ? 336.856 305.867 380.915 1.00 37.88  ? 111 GLU C N   1 
ATOM 4514 C CA  . GLU E 1 112 ? 337.912 305.234 380.137 1.00 37.88  ? 111 GLU C CA  1 
ATOM 4515 C C   . GLU E 1 112 ? 338.173 305.993 378.845 1.00 37.88  ? 111 GLU C C   1 
ATOM 4516 O O   . GLU E 1 112 ? 339.331 306.197 378.465 1.00 37.88  ? 111 GLU C O   1 
ATOM 4517 C CB  . GLU E 1 112 ? 337.541 303.782 379.846 1.00 37.88  ? 111 GLU C CB  1 
ATOM 4518 C CG  . GLU E 1 112 ? 338.246 303.182 378.651 1.00 37.88  ? 111 GLU C CG  1 
ATOM 4519 C CD  . GLU E 1 112 ? 337.831 301.748 378.403 1.00 37.88  ? 111 GLU C CD  1 
ATOM 4520 O OE1 . GLU E 1 112 ? 336.772 301.340 378.918 1.00 37.88  ? 111 GLU C OE1 1 
ATOM 4521 O OE2 . GLU E 1 112 ? 338.564 301.028 377.693 1.00 37.88  ? 111 GLU C OE2 1 
ATOM 4522 N N   . LEU E 1 113 ? 337.114 306.421 378.154 1.00 33.51  ? 112 LEU C N   1 
ATOM 4523 C CA  . LEU E 1 113 ? 337.307 307.221 376.948 1.00 33.51  ? 112 LEU C CA  1 
ATOM 4524 C C   . LEU E 1 113 ? 337.992 308.545 377.267 1.00 33.51  ? 112 LEU C C   1 
ATOM 4525 O O   . LEU E 1 113 ? 338.897 308.980 376.541 1.00 33.51  ? 112 LEU C O   1 
ATOM 4526 C CB  . LEU E 1 113 ? 335.967 307.467 376.259 1.00 33.51  ? 112 LEU C CB  1 
ATOM 4527 C CG  . LEU E 1 113 ? 336.023 308.340 375.006 1.00 33.51  ? 112 LEU C CG  1 
ATOM 4528 C CD1 . LEU E 1 113 ? 336.967 307.739 373.992 1.00 33.51  ? 112 LEU C CD1 1 
ATOM 4529 C CD2 . LEU E 1 113 ? 334.642 308.503 374.408 1.00 33.51  ? 112 LEU C CD2 1 
ATOM 4530 N N   . ALA E 1 114 ? 337.575 309.199 378.353 1.00 33.83  ? 113 ALA C N   1 
ATOM 4531 C CA  . ALA E 1 114 ? 338.183 310.473 378.721 1.00 33.83  ? 113 ALA C CA  1 
ATOM 4532 C C   . ALA E 1 114 ? 339.664 310.308 379.039 1.00 33.83  ? 113 ALA C C   1 
ATOM 4533 O O   . ALA E 1 114 ? 340.480 311.165 378.684 1.00 33.83  ? 113 ALA C O   1 
ATOM 4534 C CB  . ALA E 1 114 ? 337.447 311.087 379.910 1.00 33.83  ? 113 ALA C CB  1 
ATOM 4535 N N   . ALA E 1 115 ? 340.028 309.219 379.718 1.00 34.34  ? 114 ALA C N   1 
ATOM 4536 C CA  . ALA E 1 115 ? 341.433 308.976 380.024 1.00 34.34  ? 114 ALA C CA  1 
ATOM 4537 C C   . ALA E 1 115 ? 342.225 308.589 378.783 1.00 34.34  ? 114 ALA C C   1 
ATOM 4538 O O   . ALA E 1 115 ? 343.404 308.942 378.670 1.00 34.34  ? 114 ALA C O   1 
ATOM 4539 C CB  . ALA E 1 115 ? 341.559 307.891 381.091 1.00 34.34  ? 114 ALA C CB  1 
ATOM 4540 N N   . LEU E 1 116 ? 341.609 307.856 377.855 1.00 35.24  ? 115 LEU C N   1 
ATOM 4541 C CA  . LEU E 1 116 ? 342.287 307.499 376.615 1.00 35.24  ? 115 LEU C CA  1 
ATOM 4542 C C   . LEU E 1 116 ? 342.621 308.734 375.797 1.00 35.24  ? 115 LEU C C   1 
ATOM 4543 O O   . LEU E 1 116 ? 343.707 308.826 375.215 1.00 35.24  ? 115 LEU C O   1 
ATOM 4544 C CB  . LEU E 1 116 ? 341.421 306.550 375.793 1.00 35.24  ? 115 LEU C CB  1 
ATOM 4545 C CG  . LEU E 1 116 ? 341.701 305.057 375.900 1.00 35.24  ? 115 LEU C CG  1 
ATOM 4546 C CD1 . LEU E 1 116 ? 340.755 304.300 374.996 1.00 35.24  ? 115 LEU C CD1 1 
ATOM 4547 C CD2 . LEU E 1 116 ? 343.140 304.764 375.536 1.00 35.24  ? 115 LEU C CD2 1 
ATOM 4548 N N   . LEU E 1 117 ? 341.698 309.695 375.737 1.00 33.59  ? 116 LEU C N   1 
ATOM 4549 C CA  . LEU E 1 117 ? 341.934 310.879 374.916 1.00 33.59  ? 116 LEU C CA  1 
ATOM 4550 C C   . LEU E 1 117 ? 343.121 311.702 375.398 1.00 33.59  ? 116 LEU C C   1 
ATOM 4551 O O   . LEU E 1 117 ? 343.604 312.560 374.655 1.00 33.59  ? 116 LEU C O   1 
ATOM 4552 C CB  . LEU E 1 117 ? 340.683 311.753 374.870 1.00 33.59  ? 116 LEU C CB  1 
ATOM 4553 C CG  . LEU E 1 117 ? 339.620 311.299 373.872 1.00 33.59  ? 116 LEU C CG  1 
ATOM 4554 C CD1 . LEU E 1 117 ? 338.408 312.198 373.940 1.00 33.59  ? 116 LEU C CD1 1 
ATOM 4555 C CD2 . LEU E 1 117 ? 340.190 311.270 372.471 1.00 33.59  ? 116 LEU C CD2 1 
ATOM 4556 N N   . ALA E 1 118 ? 343.595 311.477 376.620 1.00 36.12  ? 117 ALA C N   1 
ATOM 4557 C CA  . ALA E 1 118 ? 344.755 312.179 377.148 1.00 36.12  ? 117 ALA C CA  1 
ATOM 4558 C C   . ALA E 1 118 ? 346.005 311.312 377.198 1.00 36.12  ? 117 ALA C C   1 
ATOM 4559 O O   . ALA E 1 118 ? 347.041 311.772 377.685 1.00 36.12  ? 117 ALA C O   1 
ATOM 4560 C CB  . ALA E 1 118 ? 344.451 312.724 378.544 1.00 36.12  ? 117 ALA C CB  1 
ATOM 4561 N N   . SER E 1 119 ? 345.933 310.076 376.720 1.00 39.94  ? 118 SER C N   1 
ATOM 4562 C CA  . SER E 1 119 ? 347.088 309.194 376.690 1.00 39.94  ? 118 SER C CA  1 
ATOM 4563 C C   . SER E 1 119 ? 348.024 309.585 375.549 1.00 39.94  ? 118 SER C C   1 
ATOM 4564 O O   . SER E 1 119 ? 347.584 310.159 374.552 1.00 39.94  ? 118 SER C O   1 
ATOM 4565 C CB  . SER E 1 119 ? 346.642 307.750 376.514 1.00 39.94  ? 118 SER C CB  1 
ATOM 4566 O OG  . SER E 1 119 ? 346.191 307.524 375.193 1.00 39.94  ? 118 SER C OG  1 
ATOM 4567 N N   . PRO E 1 120 ? 349.319 309.278 375.669 1.00 43.16  ? 119 PRO C N   1 
ATOM 4568 C CA  . PRO E 1 120 ? 350.255 309.641 374.591 1.00 43.16  ? 119 PRO C CA  1 
ATOM 4569 C C   . PRO E 1 120 ? 349.903 309.036 373.245 1.00 43.16  ? 119 PRO C C   1 
ATOM 4570 O O   . PRO E 1 120 ? 350.215 309.644 372.213 1.00 43.16  ? 119 PRO C O   1 
ATOM 4571 C CB  . PRO E 1 120 ? 351.607 309.120 375.103 1.00 43.16  ? 119 PRO C CB  1 
ATOM 4572 C CG  . PRO E 1 120 ? 351.280 308.179 376.210 1.00 43.16  ? 119 PRO C CG  1 
ATOM 4573 C CD  . PRO E 1 120 ? 350.010 308.671 376.815 1.00 43.16  ? 119 PRO C CD  1 
ATOM 4574 N N   . LEU E 1 121 ? 349.255 307.869 373.220 1.00 42.46  ? 120 LEU C N   1 
ATOM 4575 C CA  . LEU E 1 121 ? 348.861 307.265 371.952 1.00 42.46  ? 120 LEU C CA  1 
ATOM 4576 C C   . LEU E 1 121 ? 347.948 308.187 371.153 1.00 42.46  ? 120 LEU C C   1 
ATOM 4577 O O   . LEU E 1 121 ? 348.203 308.448 369.973 1.00 42.46  ? 120 LEU C O   1 
ATOM 4578 C CB  . LEU E 1 121 ? 348.177 305.924 372.205 1.00 42.46  ? 120 LEU C CB  1 
ATOM 4579 C CG  . LEU E 1 121 ? 347.620 305.193 370.985 1.00 42.46  ? 120 LEU C CG  1 
ATOM 4580 C CD1 . LEU E 1 121 ? 348.710 304.923 369.967 1.00 42.46  ? 120 LEU C CD1 1 
ATOM 4581 C CD2 . LEU E 1 121 ? 346.960 303.902 371.413 1.00 42.46  ? 120 LEU C CD2 1 
ATOM 4582 N N   . LEU E 1 122 ? 346.889 308.699 371.775 1.00 40.43  ? 121 LEU C N   1 
ATOM 4583 C CA  . LEU E 1 122 ? 345.965 309.593 371.086 1.00 40.43  ? 121 LEU C CA  1 
ATOM 4584 C C   . LEU E 1 122 ? 346.534 310.990 370.885 1.00 40.43  ? 121 LEU C C   1 
ATOM 4585 O O   . LEU E 1 122 ? 346.302 311.599 369.832 1.00 40.43  ? 121 LEU C O   1 
ATOM 4586 C CB  . LEU E 1 122 ? 344.644 309.679 371.854 1.00 40.43  ? 121 LEU C CB  1 
ATOM 4587 C CG  . LEU E 1 122 ? 343.542 308.699 371.445 1.00 40.43  ? 121 LEU C CG  1 
ATOM 4588 C CD1 . LEU E 1 122 ? 343.080 308.990 370.033 1.00 40.43  ? 121 LEU C CD1 1 
ATOM 4589 C CD2 . LEU E 1 122 ? 344.005 307.260 371.564 1.00 40.43  ? 121 LEU C CD2 1 
ATOM 4590 N N   . ILE E 1 123 ? 347.282 311.506 371.865 1.00 42.91  ? 122 ILE C N   1 
ATOM 4591 C CA  . ILE E 1 123 ? 347.973 312.778 371.700 1.00 42.91  ? 122 ILE C CA  1 
ATOM 4592 C C   . ILE E 1 123 ? 348.898 312.744 370.496 1.00 42.91  ? 122 ILE C C   1 
ATOM 4593 O O   . ILE E 1 123 ? 349.112 313.772 369.848 1.00 42.91  ? 122 ILE C O   1 
ATOM 4594 C CB  . ILE E 1 123 ? 348.750 313.139 372.987 1.00 42.91  ? 122 ILE C CB  1 
ATOM 4595 C CG1 . ILE E 1 123 ? 347.799 313.241 374.177 1.00 42.91  ? 122 ILE C CG1 1 
ATOM 4596 C CG2 . ILE E 1 123 ? 349.514 314.437 372.821 1.00 42.91  ? 122 ILE C CG2 1 
ATOM 4597 C CD1 . ILE E 1 123 ? 346.739 314.313 374.018 1.00 42.91  ? 122 ILE C CD1 1 
ATOM 4598 N N   . ASP E 1 124 ? 349.441 311.579 370.164 1.00 45.61  ? 123 ASP C N   1 
ATOM 4599 C CA  . ASP E 1 124 ? 350.275 311.417 368.983 1.00 45.61  ? 123 ASP C CA  1 
ATOM 4600 C C   . ASP E 1 124 ? 349.472 311.154 367.719 1.00 45.61  ? 123 ASP C C   1 
ATOM 4601 O O   . ASP E 1 124 ? 349.786 311.716 366.671 1.00 45.61  ? 123 ASP C O   1 
ATOM 4602 C CB  . ASP E 1 124 ? 351.268 310.273 369.201 1.00 45.61  ? 123 ASP C CB  1 
ATOM 4603 C CG  . ASP E 1 124 ? 352.131 310.009 367.988 1.00 45.61  ? 123 ASP C CG  1 
ATOM 4604 O OD1 . ASP E 1 124 ? 352.411 310.965 367.236 1.00 45.61  ? 123 ASP C OD1 1 
ATOM 4605 O OD2 . ASP E 1 124 ? 352.532 308.844 367.788 1.00 45.61  ? 123 ASP C OD2 1 
ATOM 4606 N N   . ALA E 1 125 ? 348.425 310.334 367.797 1.00 43.64  ? 124 ALA C N   1 
ATOM 4607 C CA  . ALA E 1 125 ? 347.660 309.947 366.620 1.00 43.64  ? 124 ALA C CA  1 
ATOM 4608 C C   . ALA E 1 125 ? 346.702 311.023 366.131 1.00 43.64  ? 124 ALA C C   1 
ATOM 4609 O O   . ALA E 1 125 ? 346.184 310.894 365.019 1.00 43.64  ? 124 ALA C O   1 
ATOM 4610 C CB  . ALA E 1 125 ? 346.868 308.669 366.902 1.00 43.64  ? 124 ALA C CB  1 
ATOM 4611 N N   . ILE E 1 126 ? 346.440 312.066 366.918 1.00 43.25  ? 125 ILE C N   1 
ATOM 4612 C CA  . ILE E 1 126 ? 345.541 313.141 366.516 1.00 43.25  ? 125 ILE C CA  1 
ATOM 4613 C C   . ILE E 1 126 ? 346.303 314.424 366.206 1.00 43.25  ? 125 ILE C C   1 
ATOM 4614 O O   . ILE E 1 126 ? 346.106 315.035 365.152 1.00 43.25  ? 125 ILE C O   1 
ATOM 4615 C CB  . ILE E 1 126 ? 344.454 313.397 367.580 1.00 43.25  ? 125 ILE C CB  1 
ATOM 4616 C CG1 . ILE E 1 126 ? 343.673 312.111 367.845 1.00 43.25  ? 125 ILE C CG1 1 
ATOM 4617 C CG2 . ILE E 1 126 ? 343.520 314.495 367.124 1.00 43.25  ? 125 ILE C CG2 1 
ATOM 4618 C CD1 . ILE E 1 126 ? 342.380 312.325 368.580 1.00 43.25  ? 125 ILE C CD1 1 
ATOM 4619 N N   . ASP E 1 127 ? 347.177 314.852 367.116 1.00 47.42  ? 126 ASP C N   1 
ATOM 4620 C CA  . ASP E 1 127 ? 347.922 316.088 366.895 1.00 47.42  ? 126 ASP C CA  1 
ATOM 4621 C C   . ASP E 1 127 ? 348.854 315.970 365.695 1.00 47.42  ? 126 ASP C C   1 
ATOM 4622 O O   . ASP E 1 127 ? 348.939 316.892 364.875 1.00 47.42  ? 126 ASP C O   1 
ATOM 4623 C CB  . ASP E 1 127 ? 348.715 316.451 368.146 1.00 47.42  ? 126 ASP C CB  1 
ATOM 4624 C CG  . ASP E 1 127 ? 347.828 316.787 369.317 1.00 47.42  ? 126 ASP C CG  1 
ATOM 4625 O OD1 . ASP E 1 127 ? 346.688 316.287 369.358 1.00 47.42  ? 126 ASP C OD1 1 
ATOM 4626 O OD2 . ASP E 1 127 ? 348.274 317.545 370.201 1.00 47.42  ? 126 ASP C OD2 1 
ATOM 4627 N N   . GLN E 1 128 ? 349.559 314.846 365.573 1.00 47.57  ? 127 GLN C N   1 
ATOM 4628 C CA  . GLN E 1 128 ? 350.539 314.660 364.513 1.00 47.57  ? 127 GLN C CA  1 
ATOM 4629 C C   . GLN E 1 128 ? 350.010 313.864 363.327 1.00 47.57  ? 127 GLN C C   1 
ATOM 4630 O O   . GLN E 1 128 ? 350.676 313.823 362.290 1.00 47.57  ? 127 GLN C O   1 
ATOM 4631 C CB  . GLN E 1 128 ? 351.789 313.969 365.065 1.00 47.57  ? 127 GLN C CB  1 
ATOM 4632 C CG  . GLN E 1 128 ? 352.842 314.925 365.589 1.00 47.57  ? 127 GLN C CG  1 
ATOM 4633 C CD  . GLN E 1 128 ? 352.465 315.529 366.922 1.00 47.57  ? 127 GLN C CD  1 
ATOM 4634 O OE1 . GLN E 1 128 ? 352.617 314.898 367.968 1.00 47.57  ? 127 GLN C OE1 1 
ATOM 4635 N NE2 . GLN E 1 128 ? 351.968 316.758 366.895 1.00 47.57  ? 127 GLN C NE2 1 
ATOM 4636 N N   . LEU E 1 129 ? 348.840 313.240 363.456 1.00 46.77  ? 128 LEU C N   1 
ATOM 4637 C CA  . LEU E 1 129 ? 348.187 312.527 362.356 1.00 46.77  ? 128 LEU C CA  1 
ATOM 4638 C C   . LEU E 1 129 ? 349.053 311.397 361.806 1.00 46.77  ? 128 LEU C C   1 
ATOM 4639 O O   . LEU E 1 129 ? 349.106 311.170 360.597 1.00 46.77  ? 128 LEU C O   1 
ATOM 4640 C CB  . LEU E 1 129 ? 347.791 313.489 361.234 1.00 46.77  ? 128 LEU C CB  1 
ATOM 4641 C CG  . LEU E 1 129 ? 346.466 314.223 361.398 1.00 46.77  ? 128 LEU C CG  1 
ATOM 4642 C CD1 . LEU E 1 129 ? 346.394 315.384 360.433 1.00 46.77  ? 128 LEU C CD1 1 
ATOM 4643 C CD2 . LEU E 1 129 ? 345.313 313.270 361.167 1.00 46.77  ? 128 LEU C CD2 1 
ATOM 4644 N N   . ASN E 1 130 ? 349.731 310.673 362.693 1.00 47.66  ? 129 ASN C N   1 
ATOM 4645 C CA  . ASN E 1 130 ? 350.512 309.529 362.254 1.00 47.66  ? 129 ASN C CA  1 
ATOM 4646 C C   . ASN E 1 130 ? 349.885 308.237 362.751 1.00 47.66  ? 129 ASN C C   1 
ATOM 4647 O O   . ASN E 1 130 ? 349.583 308.116 363.945 1.00 47.66  ? 129 ASN C O   1 
ATOM 4648 C CB  . ASN E 1 130 ? 351.961 309.629 362.743 1.00 47.66  ? 129 ASN C CB  1 
ATOM 4649 C CG  . ASN E 1 130 ? 352.060 309.749 364.237 1.00 47.66  ? 129 ASN C CG  1 
ATOM 4650 O OD1 . ASN E 1 130 ? 351.114 310.167 364.893 1.00 47.66  ? 129 ASN C OD1 1 
ATOM 4651 N ND2 . ASN E 1 130 ? 353.208 309.382 364.790 1.00 47.66  ? 129 ASN C ND2 1 
ATOM 4652 N N   . PRO E 1 131 ? 349.671 307.259 361.873 1.00 51.08  ? 130 PRO C N   1 
ATOM 4653 C CA  . PRO E 1 131 ? 349.020 306.016 362.295 1.00 51.08  ? 130 PRO C CA  1 
ATOM 4654 C C   . PRO E 1 131 ? 349.845 305.269 363.329 1.00 51.08  ? 130 PRO C C   1 
ATOM 4655 O O   . PRO E 1 131 ? 351.073 305.363 363.365 1.00 51.08  ? 130 PRO C O   1 
ATOM 4656 C CB  . PRO E 1 131 ? 348.907 305.212 360.995 1.00 51.08  ? 130 PRO C CB  1 
ATOM 4657 C CG  . PRO E 1 131 ? 349.084 306.198 359.902 1.00 51.08  ? 130 PRO C CG  1 
ATOM 4658 C CD  . PRO E 1 131 ? 349.976 307.265 360.436 1.00 51.08  ? 130 PRO C CD  1 
ATOM 4659 N N   . ALA E 1 132 ? 349.149 304.526 364.183 1.00 54.84  ? 131 ALA C N   1 
ATOM 4660 C CA  . ALA E 1 132 ? 349.795 303.652 365.151 1.00 54.84  ? 131 ALA C CA  1 
ATOM 4661 C C   . ALA E 1 132 ? 350.014 302.278 364.536 1.00 54.84  ? 131 ALA C C   1 
ATOM 4662 O O   . ALA E 1 132 ? 349.132 301.737 363.863 1.00 54.84  ? 131 ALA C O   1 
ATOM 4663 C CB  . ALA E 1 132 ? 348.955 303.532 366.422 1.00 54.84  ? 131 ALA C CB  1 
ATOM 4664 N N   . TYR E 1 133 ? 351.196 301.719 364.765 1.00 56.90  ? 132 TYR C N   1 
ATOM 4665 C CA  . TYR E 1 133 ? 351.556 300.438 364.172 1.00 56.90  ? 132 TYR C CA  1 
ATOM 4666 C C   . TYR E 1 133 ? 352.232 299.532 365.193 1.00 56.90  ? 132 TYR C C   1 
ATOM 4667 O O   . TYR E 1 133 ? 352.962 300.000 366.064 1.00 56.90  ? 132 TYR C O   1 
ATOM 4668 C CB  . TYR E 1 133 ? 352.470 300.647 362.963 1.00 56.90  ? 132 TYR C CB  1 
ATOM 4669 C CG  . TYR E 1 133 ? 353.774 301.332 363.296 1.00 56.90  ? 132 TYR C CG  1 
ATOM 4670 C CD1 . TYR E 1 133 ? 353.853 302.713 363.380 1.00 56.90  ? 132 TYR C CD1 1 
ATOM 4671 C CD2 . TYR E 1 133 ? 354.927 300.598 363.527 1.00 56.90  ? 132 TYR C CD2 1 
ATOM 4672 C CE1 . TYR E 1 133 ? 355.040 303.342 363.687 1.00 56.90  ? 132 TYR C CE1 1 
ATOM 4673 C CE2 . TYR E 1 133 ? 356.117 301.218 363.833 1.00 56.90  ? 132 TYR C CE2 1 
ATOM 4674 C CZ  . TYR E 1 133 ? 356.169 302.590 363.911 1.00 56.90  ? 132 TYR C CZ  1 
ATOM 4675 O OH  . TYR E 1 133 ? 357.354 303.214 364.217 1.00 56.90  ? 132 TYR C OH  1 
# 
