data_8W5P
# 
_entry.id   8W5P 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8W5P         pdb_00008w5p 10.2210/pdb8w5p/pdb 
WWPDB D_1300040612 ?            ?                   
EMDB  EMD-37300    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-02-26 ? 
2 'EM metadata'     1 0 2025-02-26 ? 
3 'Half map'        1 0 2025-02-26 1 
4 'Half map'        1 0 2025-02-26 2 
5 Image             1 0 2025-02-26 ? 
6 'Primary map'     1 0 2025-02-26 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Half map'        repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 Image             repository 'Initial release' ? ? 
6 6 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8W5P 
_pdbx_database_status.recvd_initial_deposition_date   2023-08-27 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure of Qb-Ab40' 
_pdbx_database_related.db_id          EMD-37300 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              zhup@ibp.ac.cn 
_pdbx_contact_author.name_first         Ping 
_pdbx_contact_author.name_last          Zhu 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-2648-3170 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Bao, K.Y.' 1 ? 
'Hua, Z.L.' 2 ? 
'Hou, B.D.' 3 ? 
'Zhu, P.'   4 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Cell Rep' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2211-1247 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            44 
_citation.language                  ? 
_citation.page_first                115334 
_citation.page_last                 115334 
_citation.title                     
'Competition propels, rather than limits, the success of low-affinity B cells in the germinal center response.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.celrep.2025.115334 
_citation.pdbx_database_id_PubMed   39955776 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Li, R.'  1 ? 
primary 'Bao, K.' 2 ? 
primary 'Liu, C.' 3 ? 
primary 'Ma, X.'  4 ? 
primary 'Hua, Z.' 5 ? 
primary 'Zhu, P.' 6 ? 
primary 'Hou, B.' 7 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'Light chain of Ab40'     12671.184 1 ? ? ? ? 
2 polymer man 'Heavy chain of Ab40'     13224.450 1 ? ? ? ? 
3 polymer man 'Minor capsid protein A1' 14268.071 2 ? ? ? ? 
# 
_entity_name_com.entity_id   3 
_entity_name_com.name        'Qb coat protein' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;VHSDIVMSQSPSSLAVSIGEKVTLTCKSSQSLLFSSNQKNYLAWYQQNPGQSPKLLIYWASTRESGVPDRFTGSGSGTDF
TLTISSVKAEDLAIYYCQQYFRYPAFGGGTKLEIK
;
;VHSDIVMSQSPSSLAVSIGEKVTLTCKSSQSLLFSSNQKNYLAWYQQNPGQSPKLLIYWASTRESGVPDRFTGSGSGTDF
TLTISSVKAEDLAIYYCQQYFRYPAFGGGTKLEIK
;
L   ? 
2 'polypeptide(L)' no no 
;VHSEVQLQQSGPELVKSGTSVKLSCKASGYSFTDHSLHWVKQSHGESLEWIGYFSPNNGGTIYNQKFMGKATLTVDRSSS
TAYMDLHNLTSADSAVYFCSTGWDYGPFDSWGQGTTLTVSS
;
;VHSEVQLQQSGPELVKSGTSVKLSCKASGYSFTDHSLHWVKQSHGESLEWIGYFSPNNGGTIYNQKFMGKATLTVDRSSS
TAYMDLHNLTSADSAVYFCSTGWDYGPFDSWGQGTTLTVSS
;
H   ? 
3 'polypeptide(L)' no no 
;MAKLETVTLGNIGKDGKQTLVLNPRGVNPTNGVASLSQAGAVPALEKRVTVSVSQPSRNRKNYKVQVKIQNPTACTANGS
CDPSVTRQAYADVTFSFTQYSTDEERAFVRTELAALLASPLLIDAIDQLNPAY
;
;MAKLETVTLGNIGKDGKQTLVLNPRGVNPTNGVASLSQAGAVPALEKRVTVSVSQPSRNRKNYKVQVKIQNPTACTANGS
CDPSVTRQAYADVTFSFTQYSTDEERAFVRTELAALLASPLLIDAIDQLNPAY
;
C,c ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   VAL n 
1 2   HIS n 
1 3   SER n 
1 4   ASP n 
1 5   ILE n 
1 6   VAL n 
1 7   MET n 
1 8   SER n 
1 9   GLN n 
1 10  SER n 
1 11  PRO n 
1 12  SER n 
1 13  SER n 
1 14  LEU n 
1 15  ALA n 
1 16  VAL n 
1 17  SER n 
1 18  ILE n 
1 19  GLY n 
1 20  GLU n 
1 21  LYS n 
1 22  VAL n 
1 23  THR n 
1 24  LEU n 
1 25  THR n 
1 26  CYS n 
1 27  LYS n 
1 28  SER n 
1 29  SER n 
1 30  GLN n 
1 31  SER n 
1 32  LEU n 
1 33  LEU n 
1 34  PHE n 
1 35  SER n 
1 36  SER n 
1 37  ASN n 
1 38  GLN n 
1 39  LYS n 
1 40  ASN n 
1 41  TYR n 
1 42  LEU n 
1 43  ALA n 
1 44  TRP n 
1 45  TYR n 
1 46  GLN n 
1 47  GLN n 
1 48  ASN n 
1 49  PRO n 
1 50  GLY n 
1 51  GLN n 
1 52  SER n 
1 53  PRO n 
1 54  LYS n 
1 55  LEU n 
1 56  LEU n 
1 57  ILE n 
1 58  TYR n 
1 59  TRP n 
1 60  ALA n 
1 61  SER n 
1 62  THR n 
1 63  ARG n 
1 64  GLU n 
1 65  SER n 
1 66  GLY n 
1 67  VAL n 
1 68  PRO n 
1 69  ASP n 
1 70  ARG n 
1 71  PHE n 
1 72  THR n 
1 73  GLY n 
1 74  SER n 
1 75  GLY n 
1 76  SER n 
1 77  GLY n 
1 78  THR n 
1 79  ASP n 
1 80  PHE n 
1 81  THR n 
1 82  LEU n 
1 83  THR n 
1 84  ILE n 
1 85  SER n 
1 86  SER n 
1 87  VAL n 
1 88  LYS n 
1 89  ALA n 
1 90  GLU n 
1 91  ASP n 
1 92  LEU n 
1 93  ALA n 
1 94  ILE n 
1 95  TYR n 
1 96  TYR n 
1 97  CYS n 
1 98  GLN n 
1 99  GLN n 
1 100 TYR n 
1 101 PHE n 
1 102 ARG n 
1 103 TYR n 
1 104 PRO n 
1 105 ALA n 
1 106 PHE n 
1 107 GLY n 
1 108 GLY n 
1 109 GLY n 
1 110 THR n 
1 111 LYS n 
1 112 LEU n 
1 113 GLU n 
1 114 ILE n 
1 115 LYS n 
2 1   VAL n 
2 2   HIS n 
2 3   SER n 
2 4   GLU n 
2 5   VAL n 
2 6   GLN n 
2 7   LEU n 
2 8   GLN n 
2 9   GLN n 
2 10  SER n 
2 11  GLY n 
2 12  PRO n 
2 13  GLU n 
2 14  LEU n 
2 15  VAL n 
2 16  LYS n 
2 17  SER n 
2 18  GLY n 
2 19  THR n 
2 20  SER n 
2 21  VAL n 
2 22  LYS n 
2 23  LEU n 
2 24  SER n 
2 25  CYS n 
2 26  LYS n 
2 27  ALA n 
2 28  SER n 
2 29  GLY n 
2 30  TYR n 
2 31  SER n 
2 32  PHE n 
2 33  THR n 
2 34  ASP n 
2 35  HIS n 
2 36  SER n 
2 37  LEU n 
2 38  HIS n 
2 39  TRP n 
2 40  VAL n 
2 41  LYS n 
2 42  GLN n 
2 43  SER n 
2 44  HIS n 
2 45  GLY n 
2 46  GLU n 
2 47  SER n 
2 48  LEU n 
2 49  GLU n 
2 50  TRP n 
2 51  ILE n 
2 52  GLY n 
2 53  TYR n 
2 54  PHE n 
2 55  SER n 
2 56  PRO n 
2 57  ASN n 
2 58  ASN n 
2 59  GLY n 
2 60  GLY n 
2 61  THR n 
2 62  ILE n 
2 63  TYR n 
2 64  ASN n 
2 65  GLN n 
2 66  LYS n 
2 67  PHE n 
2 68  MET n 
2 69  GLY n 
2 70  LYS n 
2 71  ALA n 
2 72  THR n 
2 73  LEU n 
2 74  THR n 
2 75  VAL n 
2 76  ASP n 
2 77  ARG n 
2 78  SER n 
2 79  SER n 
2 80  SER n 
2 81  THR n 
2 82  ALA n 
2 83  TYR n 
2 84  MET n 
2 85  ASP n 
2 86  LEU n 
2 87  HIS n 
2 88  ASN n 
2 89  LEU n 
2 90  THR n 
2 91  SER n 
2 92  ALA n 
2 93  ASP n 
2 94  SER n 
2 95  ALA n 
2 96  VAL n 
2 97  TYR n 
2 98  PHE n 
2 99  CYS n 
2 100 SER n 
2 101 THR n 
2 102 GLY n 
2 103 TRP n 
2 104 ASP n 
2 105 TYR n 
2 106 GLY n 
2 107 PRO n 
2 108 PHE n 
2 109 ASP n 
2 110 SER n 
2 111 TRP n 
2 112 GLY n 
2 113 GLN n 
2 114 GLY n 
2 115 THR n 
2 116 THR n 
2 117 LEU n 
2 118 THR n 
2 119 VAL n 
2 120 SER n 
2 121 SER n 
3 1   MET n 
3 2   ALA n 
3 3   LYS n 
3 4   LEU n 
3 5   GLU n 
3 6   THR n 
3 7   VAL n 
3 8   THR n 
3 9   LEU n 
3 10  GLY n 
3 11  ASN n 
3 12  ILE n 
3 13  GLY n 
3 14  LYS n 
3 15  ASP n 
3 16  GLY n 
3 17  LYS n 
3 18  GLN n 
3 19  THR n 
3 20  LEU n 
3 21  VAL n 
3 22  LEU n 
3 23  ASN n 
3 24  PRO n 
3 25  ARG n 
3 26  GLY n 
3 27  VAL n 
3 28  ASN n 
3 29  PRO n 
3 30  THR n 
3 31  ASN n 
3 32  GLY n 
3 33  VAL n 
3 34  ALA n 
3 35  SER n 
3 36  LEU n 
3 37  SER n 
3 38  GLN n 
3 39  ALA n 
3 40  GLY n 
3 41  ALA n 
3 42  VAL n 
3 43  PRO n 
3 44  ALA n 
3 45  LEU n 
3 46  GLU n 
3 47  LYS n 
3 48  ARG n 
3 49  VAL n 
3 50  THR n 
3 51  VAL n 
3 52  SER n 
3 53  VAL n 
3 54  SER n 
3 55  GLN n 
3 56  PRO n 
3 57  SER n 
3 58  ARG n 
3 59  ASN n 
3 60  ARG n 
3 61  LYS n 
3 62  ASN n 
3 63  TYR n 
3 64  LYS n 
3 65  VAL n 
3 66  GLN n 
3 67  VAL n 
3 68  LYS n 
3 69  ILE n 
3 70  GLN n 
3 71  ASN n 
3 72  PRO n 
3 73  THR n 
3 74  ALA n 
3 75  CYS n 
3 76  THR n 
3 77  ALA n 
3 78  ASN n 
3 79  GLY n 
3 80  SER n 
3 81  CYS n 
3 82  ASP n 
3 83  PRO n 
3 84  SER n 
3 85  VAL n 
3 86  THR n 
3 87  ARG n 
3 88  GLN n 
3 89  ALA n 
3 90  TYR n 
3 91  ALA n 
3 92  ASP n 
3 93  VAL n 
3 94  THR n 
3 95  PHE n 
3 96  SER n 
3 97  PHE n 
3 98  THR n 
3 99  GLN n 
3 100 TYR n 
3 101 SER n 
3 102 THR n 
3 103 ASP n 
3 104 GLU n 
3 105 GLU n 
3 106 ARG n 
3 107 ALA n 
3 108 PHE n 
3 109 VAL n 
3 110 ARG n 
3 111 THR n 
3 112 GLU n 
3 113 LEU n 
3 114 ALA n 
3 115 ALA n 
3 116 LEU n 
3 117 LEU n 
3 118 ALA n 
3 119 SER n 
3 120 PRO n 
3 121 LEU n 
3 122 LEU n 
3 123 ILE n 
3 124 ASP n 
3 125 ALA n 
3 126 ILE n 
3 127 ASP n 
3 128 GLN n 
3 129 LEU n 
3 130 ASN n 
3 131 PRO n 
3 132 ALA n 
3 133 TYR n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 115 ? ? ? ? ? ? ? ? ? 'Mus musculus'            10090   ? ? ? ? ? ? ? ? 'Homo sapiens'     9606 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 121 ? ? ? ? ? ? ? ? ? 'Mus musculus'            10090   ? ? ? ? ? ? ? ? 'Homo sapiens'     9606 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 133 ? ? ? ? ? ? ? ? ? 'Escherichia phage Qbeta' 2789016 ? ? ? ? ? ? ? ? 'Escherichia coli' 562  
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   VAL 1   1   ?   ?   ?   L . n 
A 1 2   HIS 2   2   ?   ?   ?   L . n 
A 1 3   SER 3   3   ?   ?   ?   L . n 
A 1 4   ASP 4   4   ?   ?   ?   L . n 
A 1 5   ILE 5   5   5   ILE ILE L . n 
A 1 6   VAL 6   6   6   VAL VAL L . n 
A 1 7   MET 7   7   7   MET MET L . n 
A 1 8   SER 8   8   8   SER SER L . n 
A 1 9   GLN 9   9   9   GLN GLN L . n 
A 1 10  SER 10  10  10  SER SER L . n 
A 1 11  PRO 11  11  11  PRO PRO L . n 
A 1 12  SER 12  12  12  SER SER L . n 
A 1 13  SER 13  13  13  SER SER L . n 
A 1 14  LEU 14  14  14  LEU LEU L . n 
A 1 15  ALA 15  15  15  ALA ALA L . n 
A 1 16  VAL 16  16  16  VAL VAL L . n 
A 1 17  SER 17  17  17  SER SER L . n 
A 1 18  ILE 18  18  18  ILE ILE L . n 
A 1 19  GLY 19  19  19  GLY GLY L . n 
A 1 20  GLU 20  20  20  GLU GLU L . n 
A 1 21  LYS 21  21  21  LYS LYS L . n 
A 1 22  VAL 22  22  22  VAL VAL L . n 
A 1 23  THR 23  23  23  THR THR L . n 
A 1 24  LEU 24  24  24  LEU LEU L . n 
A 1 25  THR 25  25  25  THR THR L . n 
A 1 26  CYS 26  26  26  CYS CYS L . n 
A 1 27  LYS 27  27  27  LYS LYS L . n 
A 1 28  SER 28  28  28  SER SER L . n 
A 1 29  SER 29  29  29  SER SER L . n 
A 1 30  GLN 30  30  30  GLN GLN L . n 
A 1 31  SER 31  31  31  SER SER L . n 
A 1 32  LEU 32  32  32  LEU LEU L . n 
A 1 33  LEU 33  33  33  LEU LEU L . n 
A 1 34  PHE 34  34  34  PHE PHE L . n 
A 1 35  SER 35  35  35  SER SER L . n 
A 1 36  SER 36  36  36  SER SER L . n 
A 1 37  ASN 37  37  37  ASN ASN L . n 
A 1 38  GLN 38  38  38  GLN GLN L . n 
A 1 39  LYS 39  39  39  LYS LYS L . n 
A 1 40  ASN 40  40  40  ASN ASN L . n 
A 1 41  TYR 41  41  41  TYR TYR L . n 
A 1 42  LEU 42  42  42  LEU LEU L . n 
A 1 43  ALA 43  43  43  ALA ALA L . n 
A 1 44  TRP 44  44  44  TRP TRP L . n 
A 1 45  TYR 45  45  45  TYR TYR L . n 
A 1 46  GLN 46  46  46  GLN GLN L . n 
A 1 47  GLN 47  47  47  GLN GLN L . n 
A 1 48  ASN 48  48  48  ASN ASN L . n 
A 1 49  PRO 49  49  49  PRO PRO L . n 
A 1 50  GLY 50  50  50  GLY GLY L . n 
A 1 51  GLN 51  51  51  GLN GLN L . n 
A 1 52  SER 52  52  52  SER SER L . n 
A 1 53  PRO 53  53  53  PRO PRO L . n 
A 1 54  LYS 54  54  54  LYS LYS L . n 
A 1 55  LEU 55  55  55  LEU LEU L . n 
A 1 56  LEU 56  56  56  LEU LEU L . n 
A 1 57  ILE 57  57  57  ILE ILE L . n 
A 1 58  TYR 58  58  58  TYR TYR L . n 
A 1 59  TRP 59  59  59  TRP TRP L . n 
A 1 60  ALA 60  60  60  ALA ALA L . n 
A 1 61  SER 61  61  61  SER SER L . n 
A 1 62  THR 62  62  62  THR THR L . n 
A 1 63  ARG 63  63  63  ARG ARG L . n 
A 1 64  GLU 64  64  64  GLU GLU L . n 
A 1 65  SER 65  65  65  SER SER L . n 
A 1 66  GLY 66  66  66  GLY GLY L . n 
A 1 67  VAL 67  67  67  VAL VAL L . n 
A 1 68  PRO 68  68  68  PRO PRO L . n 
A 1 69  ASP 69  69  69  ASP ASP L . n 
A 1 70  ARG 70  70  70  ARG ARG L . n 
A 1 71  PHE 71  71  71  PHE PHE L . n 
A 1 72  THR 72  72  72  THR THR L . n 
A 1 73  GLY 73  73  73  GLY GLY L . n 
A 1 74  SER 74  74  74  SER SER L . n 
A 1 75  GLY 75  75  75  GLY GLY L . n 
A 1 76  SER 76  76  76  SER SER L . n 
A 1 77  GLY 77  77  77  GLY GLY L . n 
A 1 78  THR 78  78  78  THR THR L . n 
A 1 79  ASP 79  79  79  ASP ASP L . n 
A 1 80  PHE 80  80  80  PHE PHE L . n 
A 1 81  THR 81  81  81  THR THR L . n 
A 1 82  LEU 82  82  82  LEU LEU L . n 
A 1 83  THR 83  83  83  THR THR L . n 
A 1 84  ILE 84  84  84  ILE ILE L . n 
A 1 85  SER 85  85  85  SER SER L . n 
A 1 86  SER 86  86  86  SER SER L . n 
A 1 87  VAL 87  87  87  VAL VAL L . n 
A 1 88  LYS 88  88  88  LYS LYS L . n 
A 1 89  ALA 89  89  89  ALA ALA L . n 
A 1 90  GLU 90  90  90  GLU GLU L . n 
A 1 91  ASP 91  91  91  ASP ASP L . n 
A 1 92  LEU 92  92  92  LEU LEU L . n 
A 1 93  ALA 93  93  93  ALA ALA L . n 
A 1 94  ILE 94  94  94  ILE ILE L . n 
A 1 95  TYR 95  95  95  TYR TYR L . n 
A 1 96  TYR 96  96  96  TYR TYR L . n 
A 1 97  CYS 97  97  97  CYS CYS L . n 
A 1 98  GLN 98  98  98  GLN GLN L . n 
A 1 99  GLN 99  99  99  GLN GLN L . n 
A 1 100 TYR 100 100 100 TYR TYR L . n 
A 1 101 PHE 101 101 101 PHE PHE L . n 
A 1 102 ARG 102 102 102 ARG ARG L . n 
A 1 103 TYR 103 103 103 TYR TYR L . n 
A 1 104 PRO 104 104 104 PRO PRO L . n 
A 1 105 ALA 105 105 105 ALA ALA L . n 
A 1 106 PHE 106 106 106 PHE PHE L . n 
A 1 107 GLY 107 107 107 GLY GLY L . n 
A 1 108 GLY 108 108 108 GLY GLY L . n 
A 1 109 GLY 109 109 109 GLY GLY L . n 
A 1 110 THR 110 110 110 THR THR L . n 
A 1 111 LYS 111 111 ?   ?   ?   L . n 
A 1 112 LEU 112 112 ?   ?   ?   L . n 
A 1 113 GLU 113 113 ?   ?   ?   L . n 
A 1 114 ILE 114 114 ?   ?   ?   L . n 
A 1 115 LYS 115 115 ?   ?   ?   L . n 
B 2 1   VAL 1   1   ?   ?   ?   H . n 
B 2 2   HIS 2   2   ?   ?   ?   H . n 
B 2 3   SER 3   3   ?   ?   ?   H . n 
B 2 4   GLU 4   4   ?   ?   ?   H . n 
B 2 5   VAL 5   5   5   VAL VAL H . n 
B 2 6   GLN 6   6   6   GLN GLN H . n 
B 2 7   LEU 7   7   7   LEU LEU H . n 
B 2 8   GLN 8   8   8   GLN GLN H . n 
B 2 9   GLN 9   9   9   GLN GLN H . n 
B 2 10  SER 10  10  10  SER SER H . n 
B 2 11  GLY 11  11  11  GLY GLY H . n 
B 2 12  PRO 12  12  12  PRO PRO H . n 
B 2 13  GLU 13  13  13  GLU GLU H . n 
B 2 14  LEU 14  14  14  LEU LEU H . n 
B 2 15  VAL 15  15  15  VAL VAL H . n 
B 2 16  LYS 16  16  16  LYS LYS H . n 
B 2 17  SER 17  17  17  SER SER H . n 
B 2 18  GLY 18  18  18  GLY GLY H . n 
B 2 19  THR 19  19  19  THR THR H . n 
B 2 20  SER 20  20  20  SER SER H . n 
B 2 21  VAL 21  21  21  VAL VAL H . n 
B 2 22  LYS 22  22  22  LYS LYS H . n 
B 2 23  LEU 23  23  23  LEU LEU H . n 
B 2 24  SER 24  24  24  SER SER H . n 
B 2 25  CYS 25  25  25  CYS CYS H . n 
B 2 26  LYS 26  26  26  LYS LYS H . n 
B 2 27  ALA 27  27  27  ALA ALA H . n 
B 2 28  SER 28  28  28  SER SER H . n 
B 2 29  GLY 29  29  29  GLY GLY H . n 
B 2 30  TYR 30  30  30  TYR TYR H . n 
B 2 31  SER 31  31  31  SER SER H . n 
B 2 32  PHE 32  32  32  PHE PHE H . n 
B 2 33  THR 33  33  33  THR THR H . n 
B 2 34  ASP 34  34  34  ASP ASP H . n 
B 2 35  HIS 35  35  35  HIS HIS H . n 
B 2 36  SER 36  36  36  SER SER H . n 
B 2 37  LEU 37  37  37  LEU LEU H . n 
B 2 38  HIS 38  38  38  HIS HIS H . n 
B 2 39  TRP 39  39  39  TRP TRP H . n 
B 2 40  VAL 40  40  40  VAL VAL H . n 
B 2 41  LYS 41  41  41  LYS LYS H . n 
B 2 42  GLN 42  42  42  GLN GLN H . n 
B 2 43  SER 43  43  43  SER SER H . n 
B 2 44  HIS 44  44  44  HIS HIS H . n 
B 2 45  GLY 45  45  45  GLY GLY H . n 
B 2 46  GLU 46  46  46  GLU GLU H . n 
B 2 47  SER 47  47  47  SER SER H . n 
B 2 48  LEU 48  48  48  LEU LEU H . n 
B 2 49  GLU 49  49  49  GLU GLU H . n 
B 2 50  TRP 50  50  50  TRP TRP H . n 
B 2 51  ILE 51  51  51  ILE ILE H . n 
B 2 52  GLY 52  52  52  GLY GLY H . n 
B 2 53  TYR 53  53  53  TYR TYR H . n 
B 2 54  PHE 54  54  54  PHE PHE H . n 
B 2 55  SER 55  55  55  SER SER H . n 
B 2 56  PRO 56  56  56  PRO PRO H . n 
B 2 57  ASN 57  57  57  ASN ASN H . n 
B 2 58  ASN 58  58  58  ASN ASN H . n 
B 2 59  GLY 59  59  59  GLY GLY H . n 
B 2 60  GLY 60  60  60  GLY GLY H . n 
B 2 61  THR 61  61  61  THR THR H . n 
B 2 62  ILE 62  62  62  ILE ILE H . n 
B 2 63  TYR 63  63  63  TYR TYR H . n 
B 2 64  ASN 64  64  64  ASN ASN H . n 
B 2 65  GLN 65  65  65  GLN GLN H . n 
B 2 66  LYS 66  66  66  LYS LYS H . n 
B 2 67  PHE 67  67  67  PHE PHE H . n 
B 2 68  MET 68  68  68  MET MET H . n 
B 2 69  GLY 69  69  69  GLY GLY H . n 
B 2 70  LYS 70  70  70  LYS LYS H . n 
B 2 71  ALA 71  71  71  ALA ALA H . n 
B 2 72  THR 72  72  72  THR THR H . n 
B 2 73  LEU 73  73  73  LEU LEU H . n 
B 2 74  THR 74  74  74  THR THR H . n 
B 2 75  VAL 75  75  75  VAL VAL H . n 
B 2 76  ASP 76  76  76  ASP ASP H . n 
B 2 77  ARG 77  77  77  ARG ARG H . n 
B 2 78  SER 78  78  78  SER SER H . n 
B 2 79  SER 79  79  79  SER SER H . n 
B 2 80  SER 80  80  80  SER SER H . n 
B 2 81  THR 81  81  81  THR THR H . n 
B 2 82  ALA 82  82  82  ALA ALA H . n 
B 2 83  TYR 83  83  83  TYR TYR H . n 
B 2 84  MET 84  84  84  MET MET H . n 
B 2 85  ASP 85  85  85  ASP ASP H . n 
B 2 86  LEU 86  86  86  LEU LEU H . n 
B 2 87  HIS 87  87  87  HIS HIS H . n 
B 2 88  ASN 88  88  88  ASN ASN H . n 
B 2 89  LEU 89  89  89  LEU LEU H . n 
B 2 90  THR 90  90  90  THR THR H . n 
B 2 91  SER 91  91  91  SER SER H . n 
B 2 92  ALA 92  92  92  ALA ALA H . n 
B 2 93  ASP 93  93  93  ASP ASP H . n 
B 2 94  SER 94  94  94  SER SER H . n 
B 2 95  ALA 95  95  95  ALA ALA H . n 
B 2 96  VAL 96  96  96  VAL VAL H . n 
B 2 97  TYR 97  97  97  TYR TYR H . n 
B 2 98  PHE 98  98  98  PHE PHE H . n 
B 2 99  CYS 99  99  99  CYS CYS H . n 
B 2 100 SER 100 100 100 SER SER H . n 
B 2 101 THR 101 101 101 THR THR H . n 
B 2 102 GLY 102 102 102 GLY GLY H . n 
B 2 103 TRP 103 103 103 TRP TRP H . n 
B 2 104 ASP 104 104 104 ASP ASP H . n 
B 2 105 TYR 105 105 105 TYR TYR H . n 
B 2 106 GLY 106 106 106 GLY GLY H . n 
B 2 107 PRO 107 107 107 PRO PRO H . n 
B 2 108 PHE 108 108 108 PHE PHE H . n 
B 2 109 ASP 109 109 109 ASP ASP H . n 
B 2 110 SER 110 110 110 SER SER H . n 
B 2 111 TRP 111 111 111 TRP TRP H . n 
B 2 112 GLY 112 112 112 GLY GLY H . n 
B 2 113 GLN 113 113 113 GLN GLN H . n 
B 2 114 GLY 114 114 114 GLY GLY H . n 
B 2 115 THR 115 115 115 THR THR H . n 
B 2 116 THR 116 116 116 THR THR H . n 
B 2 117 LEU 117 117 117 LEU LEU H . n 
B 2 118 THR 118 118 ?   ?   ?   H . n 
B 2 119 VAL 119 119 ?   ?   ?   H . n 
B 2 120 SER 120 120 ?   ?   ?   H . n 
B 2 121 SER 121 121 ?   ?   ?   H . n 
C 3 1   MET 1   0   ?   ?   ?   C . n 
C 3 2   ALA 2   1   1   ALA ALA C . n 
C 3 3   LYS 3   2   2   LYS LYS C . n 
C 3 4   LEU 4   3   3   LEU LEU C . n 
C 3 5   GLU 5   4   4   GLU GLU C . n 
C 3 6   THR 6   5   5   THR THR C . n 
C 3 7   VAL 7   6   6   VAL VAL C . n 
C 3 8   THR 8   7   7   THR THR C . n 
C 3 9   LEU 9   8   8   LEU LEU C . n 
C 3 10  GLY 10  9   9   GLY GLY C . n 
C 3 11  ASN 11  10  10  ASN ASN C . n 
C 3 12  ILE 12  11  11  ILE ILE C . n 
C 3 13  GLY 13  12  12  GLY GLY C . n 
C 3 14  LYS 14  13  13  LYS LYS C . n 
C 3 15  ASP 15  14  14  ASP ASP C . n 
C 3 16  GLY 16  15  15  GLY GLY C . n 
C 3 17  LYS 17  16  16  LYS LYS C . n 
C 3 18  GLN 18  17  17  GLN GLN C . n 
C 3 19  THR 19  18  18  THR THR C . n 
C 3 20  LEU 20  19  19  LEU LEU C . n 
C 3 21  VAL 21  20  20  VAL VAL C . n 
C 3 22  LEU 22  21  21  LEU LEU C . n 
C 3 23  ASN 23  22  22  ASN ASN C . n 
C 3 24  PRO 24  23  23  PRO PRO C . n 
C 3 25  ARG 25  24  24  ARG ARG C . n 
C 3 26  GLY 26  25  25  GLY GLY C . n 
C 3 27  VAL 27  26  26  VAL VAL C . n 
C 3 28  ASN 28  27  27  ASN ASN C . n 
C 3 29  PRO 29  28  28  PRO PRO C . n 
C 3 30  THR 30  29  29  THR THR C . n 
C 3 31  ASN 31  30  30  ASN ASN C . n 
C 3 32  GLY 32  31  31  GLY GLY C . n 
C 3 33  VAL 33  32  32  VAL VAL C . n 
C 3 34  ALA 34  33  33  ALA ALA C . n 
C 3 35  SER 35  34  34  SER SER C . n 
C 3 36  LEU 36  35  35  LEU LEU C . n 
C 3 37  SER 37  36  36  SER SER C . n 
C 3 38  GLN 38  37  37  GLN GLN C . n 
C 3 39  ALA 39  38  38  ALA ALA C . n 
C 3 40  GLY 40  39  39  GLY GLY C . n 
C 3 41  ALA 41  40  40  ALA ALA C . n 
C 3 42  VAL 42  41  41  VAL VAL C . n 
C 3 43  PRO 43  42  42  PRO PRO C . n 
C 3 44  ALA 44  43  43  ALA ALA C . n 
C 3 45  LEU 45  44  44  LEU LEU C . n 
C 3 46  GLU 46  45  45  GLU GLU C . n 
C 3 47  LYS 47  46  46  LYS LYS C . n 
C 3 48  ARG 48  47  47  ARG ARG C . n 
C 3 49  VAL 49  48  48  VAL VAL C . n 
C 3 50  THR 50  49  49  THR THR C . n 
C 3 51  VAL 51  50  50  VAL VAL C . n 
C 3 52  SER 52  51  51  SER SER C . n 
C 3 53  VAL 53  52  52  VAL VAL C . n 
C 3 54  SER 54  53  53  SER SER C . n 
C 3 55  GLN 55  54  54  GLN GLN C . n 
C 3 56  PRO 56  55  55  PRO PRO C . n 
C 3 57  SER 57  56  ?   ?   ?   C . n 
C 3 58  ARG 58  57  ?   ?   ?   C . n 
C 3 59  ASN 59  58  ?   ?   ?   C . n 
C 3 60  ARG 60  59  ?   ?   ?   C . n 
C 3 61  LYS 61  60  ?   ?   ?   C . n 
C 3 62  ASN 62  61  61  ASN ASN C . n 
C 3 63  TYR 63  62  62  TYR TYR C . n 
C 3 64  LYS 64  63  63  LYS LYS C . n 
C 3 65  VAL 65  64  64  VAL VAL C . n 
C 3 66  GLN 66  65  65  GLN GLN C . n 
C 3 67  VAL 67  66  66  VAL VAL C . n 
C 3 68  LYS 68  67  67  LYS LYS C . n 
C 3 69  ILE 69  68  68  ILE ILE C . n 
C 3 70  GLN 70  69  69  GLN GLN C . n 
C 3 71  ASN 71  70  70  ASN ASN C . n 
C 3 72  PRO 72  71  71  PRO PRO C . n 
C 3 73  THR 73  72  72  THR THR C . n 
C 3 74  ALA 74  73  73  ALA ALA C . n 
C 3 75  CYS 75  74  74  CYS CYS C . n 
C 3 76  THR 76  75  75  THR THR C . n 
C 3 77  ALA 77  76  76  ALA ALA C . n 
C 3 78  ASN 78  77  77  ASN ASN C . n 
C 3 79  GLY 79  78  78  GLY GLY C . n 
C 3 80  SER 80  79  79  SER SER C . n 
C 3 81  CYS 81  80  80  CYS CYS C . n 
C 3 82  ASP 82  81  81  ASP ASP C . n 
C 3 83  PRO 83  82  82  PRO PRO C . n 
C 3 84  SER 84  83  83  SER SER C . n 
C 3 85  VAL 85  84  84  VAL VAL C . n 
C 3 86  THR 86  85  85  THR THR C . n 
C 3 87  ARG 87  86  86  ARG ARG C . n 
C 3 88  GLN 88  87  87  GLN GLN C . n 
C 3 89  ALA 89  88  88  ALA ALA C . n 
C 3 90  TYR 90  89  89  TYR TYR C . n 
C 3 91  ALA 91  90  90  ALA ALA C . n 
C 3 92  ASP 92  91  91  ASP ASP C . n 
C 3 93  VAL 93  92  92  VAL VAL C . n 
C 3 94  THR 94  93  93  THR THR C . n 
C 3 95  PHE 95  94  94  PHE PHE C . n 
C 3 96  SER 96  95  95  SER SER C . n 
C 3 97  PHE 97  96  96  PHE PHE C . n 
C 3 98  THR 98  97  97  THR THR C . n 
C 3 99  GLN 99  98  98  GLN GLN C . n 
C 3 100 TYR 100 99  99  TYR TYR C . n 
C 3 101 SER 101 100 100 SER SER C . n 
C 3 102 THR 102 101 101 THR THR C . n 
C 3 103 ASP 103 102 102 ASP ASP C . n 
C 3 104 GLU 104 103 103 GLU GLU C . n 
C 3 105 GLU 105 104 104 GLU GLU C . n 
C 3 106 ARG 106 105 105 ARG ARG C . n 
C 3 107 ALA 107 106 106 ALA ALA C . n 
C 3 108 PHE 108 107 107 PHE PHE C . n 
C 3 109 VAL 109 108 108 VAL VAL C . n 
C 3 110 ARG 110 109 109 ARG ARG C . n 
C 3 111 THR 111 110 110 THR THR C . n 
C 3 112 GLU 112 111 111 GLU GLU C . n 
C 3 113 LEU 113 112 112 LEU LEU C . n 
C 3 114 ALA 114 113 113 ALA ALA C . n 
C 3 115 ALA 115 114 114 ALA ALA C . n 
C 3 116 LEU 116 115 115 LEU LEU C . n 
C 3 117 LEU 117 116 116 LEU LEU C . n 
C 3 118 ALA 118 117 117 ALA ALA C . n 
C 3 119 SER 119 118 118 SER SER C . n 
C 3 120 PRO 120 119 119 PRO PRO C . n 
C 3 121 LEU 121 120 120 LEU LEU C . n 
C 3 122 LEU 122 121 121 LEU LEU C . n 
C 3 123 ILE 123 122 122 ILE ILE C . n 
C 3 124 ASP 124 123 123 ASP ASP C . n 
C 3 125 ALA 125 124 124 ALA ALA C . n 
C 3 126 ILE 126 125 125 ILE ILE C . n 
C 3 127 ASP 127 126 126 ASP ASP C . n 
C 3 128 GLN 128 127 127 GLN GLN C . n 
C 3 129 LEU 129 128 128 LEU LEU C . n 
C 3 130 ASN 130 129 129 ASN ASN C . n 
C 3 131 PRO 131 130 130 PRO PRO C . n 
C 3 132 ALA 132 131 131 ALA ALA C . n 
C 3 133 TYR 133 132 ?   ?   ?   C . n 
D 3 1   MET 1   0   ?   ?   ?   c . n 
D 3 2   ALA 2   1   1   ALA ALA c . n 
D 3 3   LYS 3   2   2   LYS LYS c . n 
D 3 4   LEU 4   3   3   LEU LEU c . n 
D 3 5   GLU 5   4   4   GLU GLU c . n 
D 3 6   THR 6   5   5   THR THR c . n 
D 3 7   VAL 7   6   6   VAL VAL c . n 
D 3 8   THR 8   7   7   THR THR c . n 
D 3 9   LEU 9   8   8   LEU LEU c . n 
D 3 10  GLY 10  9   9   GLY GLY c . n 
D 3 11  ASN 11  10  10  ASN ASN c . n 
D 3 12  ILE 12  11  11  ILE ILE c . n 
D 3 13  GLY 13  12  12  GLY GLY c . n 
D 3 14  LYS 14  13  13  LYS LYS c . n 
D 3 15  ASP 15  14  14  ASP ASP c . n 
D 3 16  GLY 16  15  15  GLY GLY c . n 
D 3 17  LYS 17  16  16  LYS LYS c . n 
D 3 18  GLN 18  17  17  GLN GLN c . n 
D 3 19  THR 19  18  18  THR THR c . n 
D 3 20  LEU 20  19  19  LEU LEU c . n 
D 3 21  VAL 21  20  20  VAL VAL c . n 
D 3 22  LEU 22  21  21  LEU LEU c . n 
D 3 23  ASN 23  22  22  ASN ASN c . n 
D 3 24  PRO 24  23  23  PRO PRO c . n 
D 3 25  ARG 25  24  24  ARG ARG c . n 
D 3 26  GLY 26  25  25  GLY GLY c . n 
D 3 27  VAL 27  26  26  VAL VAL c . n 
D 3 28  ASN 28  27  27  ASN ASN c . n 
D 3 29  PRO 29  28  28  PRO PRO c . n 
D 3 30  THR 30  29  29  THR THR c . n 
D 3 31  ASN 31  30  30  ASN ASN c . n 
D 3 32  GLY 32  31  31  GLY GLY c . n 
D 3 33  VAL 33  32  32  VAL VAL c . n 
D 3 34  ALA 34  33  33  ALA ALA c . n 
D 3 35  SER 35  34  34  SER SER c . n 
D 3 36  LEU 36  35  35  LEU LEU c . n 
D 3 37  SER 37  36  36  SER SER c . n 
D 3 38  GLN 38  37  37  GLN GLN c . n 
D 3 39  ALA 39  38  38  ALA ALA c . n 
D 3 40  GLY 40  39  39  GLY GLY c . n 
D 3 41  ALA 41  40  40  ALA ALA c . n 
D 3 42  VAL 42  41  41  VAL VAL c . n 
D 3 43  PRO 43  42  42  PRO PRO c . n 
D 3 44  ALA 44  43  43  ALA ALA c . n 
D 3 45  LEU 45  44  44  LEU LEU c . n 
D 3 46  GLU 46  45  45  GLU GLU c . n 
D 3 47  LYS 47  46  46  LYS LYS c . n 
D 3 48  ARG 48  47  47  ARG ARG c . n 
D 3 49  VAL 49  48  48  VAL VAL c . n 
D 3 50  THR 50  49  49  THR THR c . n 
D 3 51  VAL 51  50  50  VAL VAL c . n 
D 3 52  SER 52  51  51  SER SER c . n 
D 3 53  VAL 53  52  52  VAL VAL c . n 
D 3 54  SER 54  53  53  SER SER c . n 
D 3 55  GLN 55  54  54  GLN GLN c . n 
D 3 56  PRO 56  55  55  PRO PRO c . n 
D 3 57  SER 57  56  ?   ?   ?   c . n 
D 3 58  ARG 58  57  ?   ?   ?   c . n 
D 3 59  ASN 59  58  ?   ?   ?   c . n 
D 3 60  ARG 60  59  ?   ?   ?   c . n 
D 3 61  LYS 61  60  60  LYS LYS c . n 
D 3 62  ASN 62  61  61  ASN ASN c . n 
D 3 63  TYR 63  62  62  TYR TYR c . n 
D 3 64  LYS 64  63  63  LYS LYS c . n 
D 3 65  VAL 65  64  64  VAL VAL c . n 
D 3 66  GLN 66  65  65  GLN GLN c . n 
D 3 67  VAL 67  66  66  VAL VAL c . n 
D 3 68  LYS 68  67  67  LYS LYS c . n 
D 3 69  ILE 69  68  68  ILE ILE c . n 
D 3 70  GLN 70  69  69  GLN GLN c . n 
D 3 71  ASN 71  70  70  ASN ASN c . n 
D 3 72  PRO 72  71  71  PRO PRO c . n 
D 3 73  THR 73  72  72  THR THR c . n 
D 3 74  ALA 74  73  73  ALA ALA c . n 
D 3 75  CYS 75  74  74  CYS CYS c . n 
D 3 76  THR 76  75  75  THR THR c . n 
D 3 77  ALA 77  76  76  ALA ALA c . n 
D 3 78  ASN 78  77  77  ASN ASN c . n 
D 3 79  GLY 79  78  78  GLY GLY c . n 
D 3 80  SER 80  79  79  SER SER c . n 
D 3 81  CYS 81  80  80  CYS CYS c . n 
D 3 82  ASP 82  81  81  ASP ASP c . n 
D 3 83  PRO 83  82  82  PRO PRO c . n 
D 3 84  SER 84  83  83  SER SER c . n 
D 3 85  VAL 85  84  84  VAL VAL c . n 
D 3 86  THR 86  85  85  THR THR c . n 
D 3 87  ARG 87  86  86  ARG ARG c . n 
D 3 88  GLN 88  87  87  GLN GLN c . n 
D 3 89  ALA 89  88  88  ALA ALA c . n 
D 3 90  TYR 90  89  89  TYR TYR c . n 
D 3 91  ALA 91  90  90  ALA ALA c . n 
D 3 92  ASP 92  91  91  ASP ASP c . n 
D 3 93  VAL 93  92  92  VAL VAL c . n 
D 3 94  THR 94  93  93  THR THR c . n 
D 3 95  PHE 95  94  94  PHE PHE c . n 
D 3 96  SER 96  95  95  SER SER c . n 
D 3 97  PHE 97  96  96  PHE PHE c . n 
D 3 98  THR 98  97  97  THR THR c . n 
D 3 99  GLN 99  98  98  GLN GLN c . n 
D 3 100 TYR 100 99  99  TYR TYR c . n 
D 3 101 SER 101 100 100 SER SER c . n 
D 3 102 THR 102 101 101 THR THR c . n 
D 3 103 ASP 103 102 102 ASP ASP c . n 
D 3 104 GLU 104 103 103 GLU GLU c . n 
D 3 105 GLU 105 104 104 GLU GLU c . n 
D 3 106 ARG 106 105 105 ARG ARG c . n 
D 3 107 ALA 107 106 106 ALA ALA c . n 
D 3 108 PHE 108 107 107 PHE PHE c . n 
D 3 109 VAL 109 108 108 VAL VAL c . n 
D 3 110 ARG 110 109 109 ARG ARG c . n 
D 3 111 THR 111 110 110 THR THR c . n 
D 3 112 GLU 112 111 111 GLU GLU c . n 
D 3 113 LEU 113 112 112 LEU LEU c . n 
D 3 114 ALA 114 113 113 ALA ALA c . n 
D 3 115 ALA 115 114 114 ALA ALA c . n 
D 3 116 LEU 116 115 115 LEU LEU c . n 
D 3 117 LEU 117 116 116 LEU LEU c . n 
D 3 118 ALA 118 117 117 ALA ALA c . n 
D 3 119 SER 119 118 118 SER SER c . n 
D 3 120 PRO 120 119 119 PRO PRO c . n 
D 3 121 LEU 121 120 120 LEU LEU c . n 
D 3 122 LEU 122 121 121 LEU LEU c . n 
D 3 123 ILE 123 122 122 ILE ILE c . n 
D 3 124 ASP 124 123 123 ASP ASP c . n 
D 3 125 ALA 125 124 124 ALA ALA c . n 
D 3 126 ILE 126 125 125 ILE ILE c . n 
D 3 127 ASP 127 126 126 ASP ASP c . n 
D 3 128 GLN 128 127 127 GLN GLN c . n 
D 3 129 LEU 129 128 128 LEU LEU c . n 
D 3 130 ASN 130 129 129 ASN ASN c . n 
D 3 131 PRO 131 130 130 PRO PRO c . n 
D 3 132 ALA 132 131 131 ALA ALA c . n 
D 3 133 TYR 133 132 132 TYR TYR c . n 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8W5P 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8W5P 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8W5P 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 8W5P 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.003 ? 3654 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.618 ? 4972 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 4.274 ? 501  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.045 ? 574  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.005 ? 641  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8W5P 
_struct.title                        'Cryo-EM structure of Qb-Ab40' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8W5P 
_struct_keywords.text            'Qb, Antibody, cryo-EM, IMMUNE SYSTEM' 
_struct_keywords.pdbx_keywords   'IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 3 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 8W5P     8W5P   ? 1 ? 1 
2 PDB 8W5P     8W5P   ? 2 ? 1 
3 UNP A1_BPQBE Q8LTE1 ? 3 
;MAKLETVTLGNIGKDGKQTLVLNPRGVNPTNGVASLSQAGAVPALEKRVTVSVSQPSRNRKNYKVQVKIQNPTACTANGS
CDPSVTRQAYADVTFSFTQYSTDEERAFVRTELAALLASPLLIDAIDQLNPAY
;
1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8W5P L 1 ? 115 ? 8W5P   1 ? 115 ? 1 115 
2 2 8W5P H 1 ? 121 ? 8W5P   1 ? 121 ? 1 121 
3 3 8W5P C 1 ? 133 ? Q8LTE1 1 ? 133 ? 0 132 
4 3 8W5P c 1 ? 133 ? Q8LTE1 1 ? 133 ? 0 132 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 AA1 THR C 102 ? LEU C 117 ? THR C 101 LEU C 116 1 ? 16 
HELX_P HELX_P2 AA2 LEU C 121 ? ILE C 126 ? LEU C 120 ILE C 125 1 ? 6  
HELX_P HELX_P3 AA3 VAL D 42  ? GLU D 46  ? VAL c 41  GLU c 45  5 ? 5  
HELX_P HELX_P4 AA4 THR D 102 ? LEU D 117 ? THR c 101 LEU c 116 1 ? 16 
HELX_P HELX_P5 AA5 SER D 119 ? ILE D 126 ? SER c 118 ILE c 125 1 ? 8  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_conn.id                            disulf1 
_struct_conn.conn_type_id                  disulf 
_struct_conn.pdbx_leaving_atom_flag        ? 
_struct_conn.pdbx_PDB_id                   ? 
_struct_conn.ptnr1_label_asym_id           B 
_struct_conn.ptnr1_label_comp_id           CYS 
_struct_conn.ptnr1_label_seq_id            25 
_struct_conn.ptnr1_label_atom_id           SG 
_struct_conn.pdbx_ptnr1_label_alt_id       ? 
_struct_conn.pdbx_ptnr1_PDB_ins_code       ? 
_struct_conn.pdbx_ptnr1_standard_comp_id   ? 
_struct_conn.ptnr1_symmetry                1_555 
_struct_conn.ptnr2_label_asym_id           B 
_struct_conn.ptnr2_label_comp_id           CYS 
_struct_conn.ptnr2_label_seq_id            99 
_struct_conn.ptnr2_label_atom_id           SG 
_struct_conn.pdbx_ptnr2_label_alt_id       ? 
_struct_conn.pdbx_ptnr2_PDB_ins_code       ? 
_struct_conn.ptnr1_auth_asym_id            H 
_struct_conn.ptnr1_auth_comp_id            CYS 
_struct_conn.ptnr1_auth_seq_id             25 
_struct_conn.ptnr2_auth_asym_id            H 
_struct_conn.ptnr2_auth_comp_id            CYS 
_struct_conn.ptnr2_auth_seq_id             99 
_struct_conn.ptnr2_symmetry                1_555 
_struct_conn.pdbx_ptnr3_label_atom_id      ? 
_struct_conn.pdbx_ptnr3_label_seq_id       ? 
_struct_conn.pdbx_ptnr3_label_comp_id      ? 
_struct_conn.pdbx_ptnr3_label_asym_id      ? 
_struct_conn.pdbx_ptnr3_label_alt_id       ? 
_struct_conn.pdbx_ptnr3_PDB_ins_code       ? 
_struct_conn.details                       ? 
_struct_conn.pdbx_dist_value               2.032 
_struct_conn.pdbx_value_order              ? 
_struct_conn.pdbx_role                     ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
_pdbx_modification_feature.ordinal                            1 
_pdbx_modification_feature.label_comp_id                      CYS 
_pdbx_modification_feature.label_asym_id                      B 
_pdbx_modification_feature.label_seq_id                       25 
_pdbx_modification_feature.label_alt_id                       ? 
_pdbx_modification_feature.modified_residue_label_comp_id     CYS 
_pdbx_modification_feature.modified_residue_label_asym_id     B 
_pdbx_modification_feature.modified_residue_label_seq_id      99 
_pdbx_modification_feature.modified_residue_label_alt_id      ? 
_pdbx_modification_feature.auth_comp_id                       CYS 
_pdbx_modification_feature.auth_asym_id                       H 
_pdbx_modification_feature.auth_seq_id                        25 
_pdbx_modification_feature.PDB_ins_code                       ? 
_pdbx_modification_feature.symmetry                           1_555 
_pdbx_modification_feature.modified_residue_auth_comp_id      CYS 
_pdbx_modification_feature.modified_residue_auth_asym_id      H 
_pdbx_modification_feature.modified_residue_auth_seq_id       99 
_pdbx_modification_feature.modified_residue_PDB_ins_code      ? 
_pdbx_modification_feature.modified_residue_symmetry          1_555 
_pdbx_modification_feature.comp_id_linking_atom               SG 
_pdbx_modification_feature.modified_residue_id_linking_atom   SG 
_pdbx_modification_feature.modified_residue_id                . 
_pdbx_modification_feature.ref_pcm_id                         . 
_pdbx_modification_feature.ref_comp_id                        . 
_pdbx_modification_feature.type                               None 
_pdbx_modification_feature.category                           'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4  ? 
AA2 ? 4  ? 
AA3 ? 4  ? 
AA4 ? 2  ? 
AA5 ? 12 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1  2  ? anti-parallel 
AA1 2  3  ? anti-parallel 
AA1 3  4  ? anti-parallel 
AA2 1  2  ? anti-parallel 
AA2 2  3  ? anti-parallel 
AA2 3  4  ? anti-parallel 
AA3 1  2  ? anti-parallel 
AA3 2  3  ? anti-parallel 
AA3 3  4  ? anti-parallel 
AA4 1  2  ? anti-parallel 
AA5 1  2  ? anti-parallel 
AA5 2  3  ? anti-parallel 
AA5 3  4  ? anti-parallel 
AA5 4  5  ? anti-parallel 
AA5 5  6  ? anti-parallel 
AA5 6  7  ? anti-parallel 
AA5 7  8  ? anti-parallel 
AA5 8  9  ? anti-parallel 
AA5 9  10 ? anti-parallel 
AA5 10 11 ? anti-parallel 
AA5 11 12 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1  MET A 7   ? GLN A 9   ? MET L 7   GLN L 9   
AA1 2  THR A 23  ? SER A 28  ? THR L 23  SER L 28  
AA1 3  ASP A 79  ? ILE A 84  ? ASP L 79  ILE L 84  
AA1 4  PHE A 71  ? SER A 74  ? PHE L 71  SER L 74  
AA2 1  THR A 62  ? ARG A 63  ? THR L 62  ARG L 63  
AA2 2  LYS A 54  ? TYR A 58  ? LYS L 54  TYR L 58  
AA2 3  LEU A 42  ? GLN A 47  ? LEU L 42  GLN L 47  
AA2 4  ILE A 94  ? GLN A 99  ? ILE L 94  GLN L 99  
AA3 1  GLN B 6   ? GLN B 8   ? GLN H 6   GLN H 8   
AA3 2  LYS B 22  ? SER B 28  ? LYS H 22  SER H 28  
AA3 3  THR B 81  ? ASP B 85  ? THR H 81  ASP H 85  
AA3 4  THR B 72  ? ASP B 76  ? THR H 72  ASP H 76  
AA4 1  TYR B 97  ? GLY B 102 ? TYR H 97  GLY H 102 
AA4 2  PHE B 108 ? THR B 115 ? PHE H 108 THR H 115 
AA5 1  VAL C 7   ? ILE C 12  ? VAL C 6   ILE C 11  
AA5 2  GLN C 18  ? ASN C 28  ? GLN C 17  ASN C 27  
AA5 3  VAL C 33  ? SER C 37  ? VAL C 32  SER C 36  
AA5 4  ARG C 48  ? VAL C 53  ? ARG C 47  VAL C 52  
AA5 5  VAL C 65  ? THR C 73  ? VAL C 64  THR C 72  
AA5 6  ARG C 87  ? PHE C 95  ? ARG C 86  PHE C 94  
AA5 7  SER D 84  ? PHE D 95  ? SER c 83  PHE c 94  
AA5 8  VAL D 65  ? CYS D 75  ? VAL c 64  CYS c 74  
AA5 9  ARG D 48  ? VAL D 53  ? ARG c 47  VAL c 52  
AA5 10 ALA D 34  ? SER D 37  ? ALA c 33  SER c 36  
AA5 11 GLN D 18  ? VAL D 27  ? GLN c 17  VAL c 26  
AA5 12 VAL D 7   ? ILE D 12  ? VAL c 6   ILE c 11  
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1  2  N SER A 8   ? N SER L 8   O LYS A 27  ? O LYS L 27  
AA1 2  3  N LEU A 24  ? N LEU L 24  O LEU A 82  ? O LEU L 82  
AA1 3  4  O THR A 83  ? O THR L 83  N THR A 72  ? N THR L 72  
AA2 1  2  O THR A 62  ? O THR L 62  N TYR A 58  ? N TYR L 58  
AA2 2  3  O LEU A 56  ? O LEU L 56  N TRP A 44  ? N TRP L 44  
AA2 3  4  N GLN A 47  ? N GLN L 47  O ILE A 94  ? O ILE L 94  
AA3 1  2  N GLN B 6   ? N GLN H 6   O SER B 28  ? O SER H 28  
AA3 2  3  N LEU B 23  ? N LEU H 23  O MET B 84  ? O MET H 84  
AA3 3  4  O THR B 81  ? O THR H 81  N ASP B 76  ? N ASP H 76  
AA4 1  2  N THR B 101 ? N THR H 101 O ASP B 109 ? O ASP H 109 
AA5 1  2  N VAL C 7   ? N VAL C 6   O LEU C 22  ? O LEU C 21  
AA5 2  3  N ASN C 23  ? N ASN C 22  O SER C 37  ? O SER C 36  
AA5 3  4  N ALA C 34  ? N ALA C 33  O VAL C 51  ? O VAL C 50  
AA5 4  5  N SER C 52  ? N SER C 51  O GLN C 66  ? O GLN C 65  
AA5 5  6  N ASN C 71  ? N ASN C 70  O ALA C 89  ? O ALA C 88  
AA5 6  7  N THR C 94  ? N THR C 93  O ASP D 92  ? O ASP c 91  
AA5 7  8  O ALA D 89  ? O ALA c 88  N ASN D 71  ? N ASN c 70  
AA5 8  9  O GLN D 66  ? O GLN c 65  N SER D 52  ? N SER c 51  
AA5 9  10 O VAL D 49  ? O VAL c 48  N LEU D 36  ? N LEU c 35  
AA5 10 11 O SER D 37  ? O SER c 36  N ASN D 23  ? N ASN c 22  
AA5 11 12 O LEU D 22  ? O LEU c 21  N VAL D 7   ? N VAL c 6   
# 
_pdbx_entry_details.entry_id                   8W5P 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_rmsd_bond.id 
_pdbx_validate_rmsd_bond.PDB_model_num 
_pdbx_validate_rmsd_bond.auth_atom_id_1 
_pdbx_validate_rmsd_bond.auth_asym_id_1 
_pdbx_validate_rmsd_bond.auth_comp_id_1 
_pdbx_validate_rmsd_bond.auth_seq_id_1 
_pdbx_validate_rmsd_bond.PDB_ins_code_1 
_pdbx_validate_rmsd_bond.label_alt_id_1 
_pdbx_validate_rmsd_bond.auth_atom_id_2 
_pdbx_validate_rmsd_bond.auth_asym_id_2 
_pdbx_validate_rmsd_bond.auth_comp_id_2 
_pdbx_validate_rmsd_bond.auth_seq_id_2 
_pdbx_validate_rmsd_bond.PDB_ins_code_2 
_pdbx_validate_rmsd_bond.label_alt_id_2 
_pdbx_validate_rmsd_bond.bond_value 
_pdbx_validate_rmsd_bond.bond_target_value 
_pdbx_validate_rmsd_bond.bond_deviation 
_pdbx_validate_rmsd_bond.bond_standard_deviation 
_pdbx_validate_rmsd_bond.linker_flag 
1 1 CB H TRP 50 ? ? CG  H TRP 50 ? ? 1.387 1.498 -0.111 0.018 N 
2 1 CG H TRP 50 ? ? CD1 H TRP 50 ? ? 1.279 1.363 -0.084 0.014 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 SER L 10  ? ? -46.40  154.25  
2  1 ALA L 15  ? ? -140.12 15.23   
3  1 LEU L 33  ? ? -91.53  56.54   
4  1 ALA L 60  ? ? 68.48   -4.01   
5  1 SER L 76  ? ? -118.93 -168.59 
6  1 SER L 86  ? ? 72.46   154.10  
7  1 ASP L 91  ? ? -141.64 22.86   
8  1 ALA L 93  ? ? 76.91   179.02  
9  1 ARG L 102 ? ? 58.61   -111.70 
10 1 ALA L 105 ? ? -160.34 119.81  
11 1 GLN H 9   ? ? 84.26   145.88  
12 1 SER H 10  ? ? -161.68 -103.09 
13 1 PRO H 12  ? ? -68.31  76.52   
14 1 SER H 17  ? ? 68.56   164.77  
15 1 THR H 19  ? ? -99.80  -61.00  
16 1 ASP H 34  ? ? -131.11 -31.70  
17 1 SER H 43  ? ? 52.44   -146.09 
18 1 SER H 47  ? ? 66.67   84.67   
19 1 LYS H 66  ? ? 56.13   10.38   
20 1 ALA H 95  ? ? -150.74 -159.51 
21 1 ALA C 40  ? ? 67.97   -3.89   
22 1 ALA c 40  ? ? 67.81   -4.06   
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8W5P 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8W5P 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.3 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               530467 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Complex of Qb-Ab40' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1,2,3 
# 
_em_imaging.entry_id                        8W5P 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TALOS ARCTICA' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            200 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1200 
_em_imaging.nominal_defocus_max             1600 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8W5P 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8W5P 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 L VAL 1   ? A VAL 1   
2  1 Y 1 L HIS 2   ? A HIS 2   
3  1 Y 1 L SER 3   ? A SER 3   
4  1 Y 1 L ASP 4   ? A ASP 4   
5  1 Y 1 L LYS 111 ? A LYS 111 
6  1 Y 1 L LEU 112 ? A LEU 112 
7  1 Y 1 L GLU 113 ? A GLU 113 
8  1 Y 1 L ILE 114 ? A ILE 114 
9  1 Y 1 L LYS 115 ? A LYS 115 
10 1 Y 1 H VAL 1   ? B VAL 1   
11 1 Y 1 H HIS 2   ? B HIS 2   
12 1 Y 1 H SER 3   ? B SER 3   
13 1 Y 1 H GLU 4   ? B GLU 4   
14 1 Y 1 H THR 118 ? B THR 118 
15 1 Y 1 H VAL 119 ? B VAL 119 
16 1 Y 1 H SER 120 ? B SER 120 
17 1 Y 1 H SER 121 ? B SER 121 
18 1 Y 1 C MET 0   ? C MET 1   
19 1 Y 1 C SER 56  ? C SER 57  
20 1 Y 1 C ARG 57  ? C ARG 58  
21 1 Y 1 C ASN 58  ? C ASN 59  
22 1 Y 1 C ARG 59  ? C ARG 60  
23 1 Y 1 C LYS 60  ? C LYS 61  
24 1 Y 1 C TYR 132 ? C TYR 133 
25 1 Y 1 c MET 0   ? D MET 1   
26 1 Y 1 c SER 56  ? D SER 57  
27 1 Y 1 c ARG 57  ? D ARG 58  
28 1 Y 1 c ASN 58  ? D ASN 59  
29 1 Y 1 c ARG 59  ? D ARG 60  
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-08-27 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8W5P 
_em_admin.last_update        2025-02-26 
_em_admin.map_release_date   2025-02-26 
_em_admin.title              'Cryo-EM structure of Qb-Ab40' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          10088 
_em_entity_assembly_naturalsource.organism             Mus 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K2 SUMMIT (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ?      ?            
'MODEL REFINEMENT'         ? 2  ? ? ? PHENIX 1.19.2_4158: 
'IMAGE ACQUISITION'        ? 3  ? ? 1 ?      ?            
MASKING                    ? 4  ? ? ? ?      ?            
'CTF CORRECTION'           ? 5  1 ? ? ?      ?            
'LAYERLINE INDEXING'       ? 6  ? ? ? ?      ?            
'DIFFRACTION INDEXING'     ? 7  ? ? ? ?      ?            
'MODEL FITTING'            ? 8  ? ? ? ?      ?            
OTHER                      ? 9  ? ? ? ?      ?            
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ?      ?            
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ?      ?            
CLASSIFICATION             ? 12 1 ? ? ?      ?            
RECONSTRUCTION             ? 13 1 ? ? ?      ?            
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Natural Science Foundation of China (NSFC)' China 81991495    1 
'National Natural Science Foundation of China (NSFC)' China 32241029    2 
'Chinese Academy of Sciences'                         China XDB29050600 3 
'Chinese Academy of Sciences'                         China XDB37010100 4 
# 
_atom_sites.entry_id                    8W5P 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . ILE A 1 5   ? 130.555 99.322  109.247 1.00 91.57  ? 5   ILE L N   1 
ATOM 2    C CA  . ILE A 1 5   ? 129.697 100.354 108.683 1.00 91.57  ? 5   ILE L CA  1 
ATOM 3    C C   . ILE A 1 5   ? 130.222 100.785 107.322 1.00 91.57  ? 5   ILE L C   1 
ATOM 4    O O   . ILE A 1 5   ? 131.422 100.991 107.148 1.00 91.57  ? 5   ILE L O   1 
ATOM 5    C CB  . ILE A 1 5   ? 129.583 101.563 109.627 1.00 91.57  ? 5   ILE L CB  1 
ATOM 6    C CG1 . ILE A 1 5   ? 129.279 101.102 111.051 1.00 91.57  ? 5   ILE L CG1 1 
ATOM 7    C CG2 . ILE A 1 5   ? 128.503 102.514 109.147 1.00 91.57  ? 5   ILE L CG2 1 
ATOM 8    C CD1 . ILE A 1 5   ? 127.946 100.412 111.193 1.00 91.57  ? 5   ILE L CD1 1 
ATOM 9    N N   . VAL A 1 6   ? 129.318 100.915 106.356 1.00 96.35  ? 6   VAL L N   1 
ATOM 10   C CA  . VAL A 1 6   ? 129.645 101.409 105.025 1.00 96.35  ? 6   VAL L CA  1 
ATOM 11   C C   . VAL A 1 6   ? 128.763 102.613 104.728 1.00 96.35  ? 6   VAL L C   1 
ATOM 12   O O   . VAL A 1 6   ? 127.565 102.611 105.031 1.00 96.35  ? 6   VAL L O   1 
ATOM 13   C CB  . VAL A 1 6   ? 129.483 100.316 103.946 1.00 96.35  ? 6   VAL L CB  1 
ATOM 14   C CG1 . VAL A 1 6   ? 130.438 99.166  104.218 1.00 96.35  ? 6   VAL L CG1 1 
ATOM 15   C CG2 . VAL A 1 6   ? 128.053 99.808  103.896 1.00 96.35  ? 6   VAL L CG2 1 
ATOM 16   N N   . MET A 1 7   ? 129.366 103.652 104.158 1.00 102.03 ? 7   MET L N   1 
ATOM 17   C CA  . MET A 1 7   ? 128.689 104.919 103.894 1.00 102.03 ? 7   MET L CA  1 
ATOM 18   C C   . MET A 1 7   ? 128.628 105.122 102.385 1.00 102.03 ? 7   MET L C   1 
ATOM 19   O O   . MET A 1 7   ? 129.577 105.632 101.781 1.00 102.03 ? 7   MET L O   1 
ATOM 20   C CB  . MET A 1 7   ? 129.413 106.072 104.582 1.00 102.03 ? 7   MET L CB  1 
ATOM 21   C CG  . MET A 1 7   ? 129.550 105.907 106.086 1.00 102.03 ? 7   MET L CG  1 
ATOM 22   S SD  . MET A 1 7   ? 127.973 105.657 106.920 1.00 102.03 ? 7   MET L SD  1 
ATOM 23   C CE  . MET A 1 7   ? 127.052 107.071 106.327 1.00 102.03 ? 7   MET L CE  1 
ATOM 24   N N   . SER A 1 8   ? 127.513 104.729 101.777 1.00 103.78 ? 8   SER L N   1 
ATOM 25   C CA  . SER A 1 8   ? 127.306 104.878 100.343 1.00 103.78 ? 8   SER L CA  1 
ATOM 26   C C   . SER A 1 8   ? 126.655 106.229 100.079 1.00 103.78 ? 8   SER L C   1 
ATOM 27   O O   . SER A 1 8   ? 125.542 106.489 100.548 1.00 103.78 ? 8   SER L O   1 
ATOM 28   C CB  . SER A 1 8   ? 126.441 103.744 99.795  1.00 103.78 ? 8   SER L CB  1 
ATOM 29   O OG  . SER A 1 8   ? 125.199 103.684 100.472 1.00 103.78 ? 8   SER L OG  1 
ATOM 30   N N   . GLN A 1 9   ? 127.346 107.079 99.329  1.00 103.07 ? 9   GLN L N   1 
ATOM 31   C CA  . GLN A 1 9   ? 126.920 108.446 99.071  1.00 103.07 ? 9   GLN L CA  1 
ATOM 32   C C   . GLN A 1 9   ? 126.517 108.593 97.606  1.00 103.07 ? 9   GLN L C   1 
ATOM 33   O O   . GLN A 1 9   ? 126.859 107.766 96.757  1.00 103.07 ? 9   GLN L O   1 
ATOM 34   C CB  . GLN A 1 9   ? 128.043 109.423 99.462  1.00 103.07 ? 9   GLN L CB  1 
ATOM 35   C CG  . GLN A 1 9   ? 127.896 110.863 98.989  1.00 103.07 ? 9   GLN L CG  1 
ATOM 36   C CD  . GLN A 1 9   ? 128.638 111.849 99.865  1.00 103.07 ? 9   GLN L CD  1 
ATOM 37   O OE1 . GLN A 1 9   ? 129.678 111.530 100.436 1.00 103.07 ? 9   GLN L OE1 1 
ATOM 38   N NE2 . GLN A 1 9   ? 128.105 113.059 99.973  1.00 103.07 ? 9   GLN L NE2 1 
ATOM 39   N N   . SER A 1 10  ? 125.757 109.659 97.325  1.00 108.67 ? 10  SER L N   1 
ATOM 40   C CA  . SER A 1 10  ? 125.286 110.056 96.001  1.00 108.67 ? 10  SER L CA  1 
ATOM 41   C C   . SER A 1 10  ? 126.424 109.999 94.987  1.00 108.67 ? 10  SER L C   1 
ATOM 42   O O   . SER A 1 10  ? 127.596 110.107 95.371  1.00 108.67 ? 10  SER L O   1 
ATOM 43   C CB  . SER A 1 10  ? 124.690 111.466 96.077  1.00 108.67 ? 10  SER L CB  1 
ATOM 44   O OG  . SER A 1 10  ? 124.243 111.937 94.818  1.00 108.67 ? 10  SER L OG  1 
ATOM 45   N N   . PRO A 1 11  ? 126.125 109.810 93.684  1.00 114.15 ? 11  PRO L N   1 
ATOM 46   C CA  . PRO A 1 11  ? 127.194 109.685 92.679  1.00 114.15 ? 11  PRO L CA  1 
ATOM 47   C C   . PRO A 1 11  ? 128.244 110.784 92.736  1.00 114.15 ? 11  PRO L C   1 
ATOM 48   O O   . PRO A 1 11  ? 128.015 111.857 93.303  1.00 114.15 ? 11  PRO L O   1 
ATOM 49   C CB  . PRO A 1 11  ? 126.427 109.716 91.346  1.00 114.15 ? 11  PRO L CB  1 
ATOM 50   C CG  . PRO A 1 11  ? 124.995 110.063 91.701  1.00 114.15 ? 11  PRO L CG  1 
ATOM 51   C CD  . PRO A 1 11  ? 124.807 109.554 93.086  1.00 114.15 ? 11  PRO L CD  1 
ATOM 52   N N   . SER A 1 12  ? 129.399 110.514 92.124  1.00 113.65 ? 12  SER L N   1 
ATOM 53   C CA  . SER A 1 12  ? 130.586 111.329 92.362  1.00 113.65 ? 12  SER L CA  1 
ATOM 54   C C   . SER A 1 12  ? 130.380 112.779 91.943  1.00 113.65 ? 12  SER L C   1 
ATOM 55   O O   . SER A 1 12  ? 130.783 113.699 92.663  1.00 113.65 ? 12  SER L O   1 
ATOM 56   C CB  . SER A 1 12  ? 131.783 110.730 91.627  1.00 113.65 ? 12  SER L CB  1 
ATOM 57   O OG  . SER A 1 12  ? 131.826 111.179 90.284  1.00 113.65 ? 12  SER L OG  1 
ATOM 58   N N   . SER A 1 13  ? 129.760 113.010 90.791  1.00 114.03 ? 13  SER L N   1 
ATOM 59   C CA  . SER A 1 13  ? 129.692 114.344 90.217  1.00 114.03 ? 13  SER L CA  1 
ATOM 60   C C   . SER A 1 13  ? 128.274 114.900 90.266  1.00 114.03 ? 13  SER L C   1 
ATOM 61   O O   . SER A 1 13  ? 127.288 114.161 90.322  1.00 114.03 ? 13  SER L O   1 
ATOM 62   C CB  . SER A 1 13  ? 130.194 114.344 88.770  1.00 114.03 ? 13  SER L CB  1 
ATOM 63   O OG  . SER A 1 13  ? 129.767 115.509 88.085  1.00 114.03 ? 13  SER L OG  1 
ATOM 64   N N   . LEU A 1 14  ? 128.193 116.225 90.251  1.00 108.66 ? 14  LEU L N   1 
ATOM 65   C CA  . LEU A 1 14  ? 126.947 116.968 90.136  1.00 108.66 ? 14  LEU L CA  1 
ATOM 66   C C   . LEU A 1 14  ? 126.983 117.796 88.852  1.00 108.66 ? 14  LEU L C   1 
ATOM 67   O O   . LEU A 1 14  ? 127.905 117.681 88.039  1.00 108.66 ? 14  LEU L O   1 
ATOM 68   C CB  . LEU A 1 14  ? 126.717 117.844 91.370  1.00 108.66 ? 14  LEU L CB  1 
ATOM 69   C CG  . LEU A 1 14  ? 125.946 117.245 92.549  1.00 108.66 ? 14  LEU L CG  1 
ATOM 70   C CD1 . LEU A 1 14  ? 124.515 116.940 92.144  1.00 108.66 ? 14  LEU L CD1 1 
ATOM 71   C CD2 . LEU A 1 14  ? 126.628 116.000 93.097  1.00 108.66 ? 14  LEU L CD2 1 
ATOM 72   N N   . ALA A 1 15  ? 125.962 118.640 88.667  1.00 111.57 ? 15  ALA L N   1 
ATOM 73   C CA  . ALA A 1 15  ? 125.882 119.446 87.455  1.00 111.57 ? 15  ALA L CA  1 
ATOM 74   C C   . ALA A 1 15  ? 125.398 120.869 87.718  1.00 111.57 ? 15  ALA L C   1 
ATOM 75   O O   . ALA A 1 15  ? 125.019 121.567 86.769  1.00 111.57 ? 15  ALA L O   1 
ATOM 76   C CB  . ALA A 1 15  ? 124.969 118.779 86.424  1.00 111.57 ? 15  ALA L CB  1 
ATOM 77   N N   . VAL A 1 16  ? 125.402 121.321 88.966  1.00 116.44 ? 16  VAL L N   1 
ATOM 78   C CA  . VAL A 1 16  ? 124.910 122.655 89.290  1.00 116.44 ? 16  VAL L CA  1 
ATOM 79   C C   . VAL A 1 16  ? 126.023 123.676 89.097  1.00 116.44 ? 16  VAL L C   1 
ATOM 80   O O   . VAL A 1 16  ? 127.187 123.430 89.437  1.00 116.44 ? 16  VAL L O   1 
ATOM 81   C CB  . VAL A 1 16  ? 124.346 122.691 90.720  1.00 116.44 ? 16  VAL L CB  1 
ATOM 82   C CG1 . VAL A 1 16  ? 123.168 121.742 90.831  1.00 116.44 ? 16  VAL L CG1 1 
ATOM 83   C CG2 . VAL A 1 16  ? 125.420 122.325 91.731  1.00 116.44 ? 16  VAL L CG2 1 
ATOM 84   N N   . SER A 1 17  ? 125.665 124.829 88.530  1.00 119.37 ? 17  SER L N   1 
ATOM 85   C CA  . SER A 1 17  ? 126.627 125.878 88.212  1.00 119.37 ? 17  SER L CA  1 
ATOM 86   C C   . SER A 1 17  ? 126.613 127.012 89.233  1.00 119.37 ? 17  SER L C   1 
ATOM 87   O O   . SER A 1 17  ? 127.645 127.315 89.839  1.00 119.37 ? 17  SER L O   1 
ATOM 88   C CB  . SER A 1 17  ? 126.350 126.429 86.807  1.00 119.37 ? 17  SER L CB  1 
ATOM 89   O OG  . SER A 1 17  ? 125.358 127.440 86.846  1.00 119.37 ? 17  SER L OG  1 
ATOM 90   N N   . ILE A 1 18  ? 125.460 127.643 89.439  1.00 118.79 ? 18  ILE L N   1 
ATOM 91   C CA  . ILE A 1 18  ? 125.389 128.840 90.270  1.00 118.79 ? 18  ILE L CA  1 
ATOM 92   C C   . ILE A 1 18  ? 123.954 129.023 90.745  1.00 118.79 ? 18  ILE L C   1 
ATOM 93   O O   . ILE A 1 18  ? 123.000 128.768 90.004  1.00 118.79 ? 18  ILE L O   1 
ATOM 94   C CB  . ILE A 1 18  ? 125.905 130.081 89.500  1.00 118.79 ? 18  ILE L CB  1 
ATOM 95   C CG1 . ILE A 1 18  ? 126.125 131.262 90.448  1.00 118.79 ? 18  ILE L CG1 1 
ATOM 96   C CG2 . ILE A 1 18  ? 124.969 130.447 88.354  1.00 118.79 ? 18  ILE L CG2 1 
ATOM 97   C CD1 . ILE A 1 18  ? 127.227 131.043 91.449  1.00 118.79 ? 18  ILE L CD1 1 
ATOM 98   N N   . GLY A 1 19  ? 123.810 129.439 92.002  1.00 116.16 ? 19  GLY L N   1 
ATOM 99   C CA  . GLY A 1 19  ? 122.528 129.860 92.535  1.00 116.16 ? 19  GLY L CA  1 
ATOM 100  C C   . GLY A 1 19  ? 121.524 128.759 92.813  1.00 116.16 ? 19  GLY L C   1 
ATOM 101  O O   . GLY A 1 19  ? 120.619 128.937 93.633  1.00 116.16 ? 19  GLY L O   1 
ATOM 102  N N   . GLU A 1 20  ? 121.670 127.621 92.141  1.00 119.53 ? 20  GLU L N   1 
ATOM 103  C CA  . GLU A 1 20  ? 120.691 126.549 92.255  1.00 119.53 ? 20  GLU L CA  1 
ATOM 104  C C   . GLU A 1 20  ? 120.696 125.947 93.654  1.00 119.53 ? 20  GLU L C   1 
ATOM 105  O O   . GLU A 1 20  ? 121.750 125.770 94.270  1.00 119.53 ? 20  GLU L O   1 
ATOM 106  C CB  . GLU A 1 20  ? 120.971 125.461 91.219  1.00 119.53 ? 20  GLU L CB  1 
ATOM 107  C CG  . GLU A 1 20  ? 120.348 125.724 89.860  1.00 119.53 ? 20  GLU L CG  1 
ATOM 108  C CD  . GLU A 1 20  ? 121.170 125.157 88.722  1.00 119.53 ? 20  GLU L CD  1 
ATOM 109  O OE1 . GLU A 1 20  ? 122.185 124.485 88.999  1.00 119.53 ? 20  GLU L OE1 1 
ATOM 110  O OE2 . GLU A 1 20  ? 120.803 125.382 87.550  1.00 119.53 ? 20  GLU L OE2 1 
ATOM 111  N N   . LYS A 1 21  ? 119.504 125.632 94.153  1.00 114.92 ? 21  LYS L N   1 
ATOM 112  C CA  . LYS A 1 21  ? 119.356 124.957 95.439  1.00 114.92 ? 21  LYS L CA  1 
ATOM 113  C C   . LYS A 1 21  ? 119.713 123.491 95.251  1.00 114.92 ? 21  LYS L C   1 
ATOM 114  O O   . LYS A 1 21  ? 118.858 122.669 94.915  1.00 114.92 ? 21  LYS L O   1 
ATOM 115  C CB  . LYS A 1 21  ? 117.933 125.111 95.963  1.00 114.92 ? 21  LYS L CB  1 
ATOM 116  C CG  . LYS A 1 21  ? 117.751 124.724 97.423  1.00 114.92 ? 21  LYS L CG  1 
ATOM 117  C CD  . LYS A 1 21  ? 118.607 125.575 98.346  1.00 114.92 ? 21  LYS L CD  1 
ATOM 118  C CE  . LYS A 1 21  ? 118.331 127.057 98.130  1.00 114.92 ? 21  LYS L CE  1 
ATOM 119  N NZ  . LYS A 1 21  ? 118.963 127.917 99.166  1.00 114.92 ? 21  LYS L NZ  1 
ATOM 120  N N   . VAL A 1 22  ? 120.981 123.152 95.463  1.00 110.62 ? 22  VAL L N   1 
ATOM 121  C CA  . VAL A 1 22  ? 121.475 121.795 95.271  1.00 110.62 ? 22  VAL L CA  1 
ATOM 122  C C   . VAL A 1 22  ? 121.623 121.127 96.630  1.00 110.62 ? 22  VAL L C   1 
ATOM 123  O O   . VAL A 1 22  ? 122.047 121.758 97.606  1.00 110.62 ? 22  VAL L O   1 
ATOM 124  C CB  . VAL A 1 22  ? 122.799 121.773 94.478  1.00 110.62 ? 22  VAL L CB  1 
ATOM 125  C CG1 . VAL A 1 22  ? 123.911 122.451 95.244  1.00 110.62 ? 22  VAL L CG1 1 
ATOM 126  C CG2 . VAL A 1 22  ? 123.190 120.342 94.142  1.00 110.62 ? 22  VAL L CG2 1 
ATOM 127  N N   . THR A 1 23  ? 121.233 119.857 96.697  1.00 108.56 ? 23  THR L N   1 
ATOM 128  C CA  . THR A 1 23  ? 121.251 119.084 97.928  1.00 108.56 ? 23  THR L CA  1 
ATOM 129  C C   . THR A 1 23  ? 122.148 117.872 97.745  1.00 108.56 ? 23  THR L C   1 
ATOM 130  O O   . THR A 1 23  ? 122.195 117.282 96.662  1.00 108.56 ? 23  THR L O   1 
ATOM 131  C CB  . THR A 1 23  ? 119.842 118.626 98.317  1.00 108.56 ? 23  THR L CB  1 
ATOM 132  O OG1 . THR A 1 23  ? 119.166 118.127 97.157  1.00 108.56 ? 23  THR L OG1 1 
ATOM 133  C CG2 . THR A 1 23  ? 119.045 119.784 98.884  1.00 108.56 ? 23  THR L CG2 1 
ATOM 134  N N   . LEU A 1 24  ? 122.860 117.506 98.805  1.00 103.53 ? 24  LEU L N   1 
ATOM 135  C CA  . LEU A 1 24  ? 123.707 116.322 98.815  1.00 103.53 ? 24  LEU L CA  1 
ATOM 136  C C   . LEU A 1 24  ? 123.065 115.262 99.696  1.00 103.53 ? 24  LEU L C   1 
ATOM 137  O O   . LEU A 1 24  ? 122.650 115.554 100.822 1.00 103.53 ? 24  LEU L O   1 
ATOM 138  C CB  . LEU A 1 24  ? 125.112 116.655 99.314  1.00 103.53 ? 24  LEU L CB  1 
ATOM 139  C CG  . LEU A 1 24  ? 126.040 117.259 98.262  1.00 103.53 ? 24  LEU L CG  1 
ATOM 140  C CD1 . LEU A 1 24  ? 127.044 118.190 98.912  1.00 103.53 ? 24  LEU L CD1 1 
ATOM 141  C CD2 . LEU A 1 24  ? 126.743 116.159 97.485  1.00 103.53 ? 24  LEU L CD2 1 
ATOM 142  N N   . THR A 1 25  ? 122.987 114.038 99.184  1.00 104.92 ? 25  THR L N   1 
ATOM 143  C CA  . THR A 1 25  ? 122.302 112.945 99.855  1.00 104.92 ? 25  THR L CA  1 
ATOM 144  C C   . THR A 1 25  ? 123.302 111.883 100.286 1.00 104.92 ? 25  THR L C   1 
ATOM 145  O O   . THR A 1 25  ? 124.203 111.519 99.525  1.00 104.92 ? 25  THR L O   1 
ATOM 146  C CB  . THR A 1 25  ? 121.252 112.317 98.940  1.00 104.92 ? 25  THR L CB  1 
ATOM 147  O OG1 . THR A 1 25  ? 121.896 111.780 97.779  1.00 104.92 ? 25  THR L OG1 1 
ATOM 148  C CG2 . THR A 1 25  ? 120.239 113.362 98.506  1.00 104.92 ? 25  THR L CG2 1 
ATOM 149  N N   . CYS A 1 26  ? 123.136 111.389 101.509 1.00 106.35 ? 26  CYS L N   1 
ATOM 150  C CA  . CYS A 1 26  ? 123.960 110.315 102.040 1.00 106.35 ? 26  CYS L CA  1 
ATOM 151  C C   . CYS A 1 26  ? 123.063 109.229 102.613 1.00 106.35 ? 26  CYS L C   1 
ATOM 152  O O   . CYS A 1 26  ? 122.015 109.512 103.199 1.00 106.35 ? 26  CYS L O   1 
ATOM 153  C CB  . CYS A 1 26  ? 124.919 110.817 103.120 1.00 106.35 ? 26  CYS L CB  1 
ATOM 154  S SG  . CYS A 1 26  ? 125.748 109.499 104.028 1.00 106.35 ? 26  CYS L SG  1 
ATOM 155  N N   . LYS A 1 27  ? 123.486 107.980 102.442 1.00 103.22 ? 27  LYS L N   1 
ATOM 156  C CA  . LYS A 1 27  ? 122.699 106.831 102.873 1.00 103.22 ? 27  LYS L CA  1 
ATOM 157  C C   . LYS A 1 27  ? 123.631 105.859 103.575 1.00 103.22 ? 27  LYS L C   1 
ATOM 158  O O   . LYS A 1 27  ? 124.682 105.506 103.035 1.00 103.22 ? 27  LYS L O   1 
ATOM 159  C CB  . LYS A 1 27  ? 121.988 106.181 101.672 1.00 103.22 ? 27  LYS L CB  1 
ATOM 160  C CG  . LYS A 1 27  ? 121.214 104.873 101.920 1.00 103.22 ? 27  LYS L CG  1 
ATOM 161  C CD  . LYS A 1 27  ? 122.095 103.630 102.021 1.00 103.22 ? 27  LYS L CD  1 
ATOM 162  C CE  . LYS A 1 27  ? 121.303 102.363 101.749 1.00 103.22 ? 27  LYS L CE  1 
ATOM 163  N NZ  . LYS A 1 27  ? 122.194 101.211 101.440 1.00 103.22 ? 27  LYS L NZ  1 
ATOM 164  N N   . SER A 1 28  ? 123.245 105.429 104.770 1.00 104.05 ? 28  SER L N   1 
ATOM 165  C CA  . SER A 1 28  ? 124.015 104.464 105.538 1.00 104.05 ? 28  SER L CA  1 
ATOM 166  C C   . SER A 1 28  ? 123.344 103.097 105.499 1.00 104.05 ? 28  SER L C   1 
ATOM 167  O O   . SER A 1 28  ? 122.151 102.969 105.218 1.00 104.05 ? 28  SER L O   1 
ATOM 168  C CB  . SER A 1 28  ? 124.173 104.925 106.988 1.00 104.05 ? 28  SER L CB  1 
ATOM 169  O OG  . SER A 1 28  ? 124.832 103.937 107.761 1.00 104.05 ? 28  SER L OG  1 
ATOM 170  N N   . SER A 1 29  ? 124.135 102.068 105.791 1.00 103.41 ? 29  SER L N   1 
ATOM 171  C CA  . SER A 1 29  ? 123.653 100.695 105.818 1.00 103.41 ? 29  SER L CA  1 
ATOM 172  C C   . SER A 1 29  ? 123.382 100.198 107.230 1.00 103.41 ? 29  SER L C   1 
ATOM 173  O O   . SER A 1 29  ? 123.175 98.996  107.424 1.00 103.41 ? 29  SER L O   1 
ATOM 174  C CB  . SER A 1 29  ? 124.652 99.770  105.124 1.00 103.41 ? 29  SER L CB  1 
ATOM 175  O OG  . SER A 1 29  ? 124.271 98.413  105.272 1.00 103.41 ? 29  SER L OG  1 
ATOM 176  N N   . GLN A 1 30  ? 123.386 101.088 108.217 1.00 103.09 ? 30  GLN L N   1 
ATOM 177  C CA  . GLN A 1 30  ? 123.112 100.698 109.591 1.00 103.09 ? 30  GLN L CA  1 
ATOM 178  C C   . GLN A 1 30  ? 122.604 101.916 110.347 1.00 103.09 ? 30  GLN L C   1 
ATOM 179  O O   . GLN A 1 30  ? 122.876 103.056 109.962 1.00 103.09 ? 30  GLN L O   1 
ATOM 180  C CB  . GLN A 1 30  ? 124.361 100.119 110.264 1.00 103.09 ? 30  GLN L CB  1 
ATOM 181  C CG  . GLN A 1 30  ? 124.070 99.201  111.434 1.00 103.09 ? 30  GLN L CG  1 
ATOM 182  C CD  . GLN A 1 30  ? 124.298 99.875  112.769 1.00 103.09 ? 30  GLN L CD  1 
ATOM 183  O OE1 . GLN A 1 30  ? 125.192 100.707 112.911 1.00 103.09 ? 30  GLN L OE1 1 
ATOM 184  N NE2 . GLN A 1 30  ? 123.487 99.519  113.758 1.00 103.09 ? 30  GLN L NE2 1 
ATOM 185  N N   . SER A 1 31  ? 121.857 101.663 111.418 1.00 102.45 ? 31  SER L N   1 
ATOM 186  C CA  . SER A 1 31  ? 121.321 102.750 112.225 1.00 102.45 ? 31  SER L CA  1 
ATOM 187  C C   . SER A 1 31  ? 122.453 103.523 112.887 1.00 102.45 ? 31  SER L C   1 
ATOM 188  O O   . SER A 1 31  ? 123.396 102.932 113.418 1.00 102.45 ? 31  SER L O   1 
ATOM 189  C CB  . SER A 1 31  ? 120.366 102.200 113.282 1.00 102.45 ? 31  SER L CB  1 
ATOM 190  O OG  . SER A 1 31  ? 121.081 101.712 114.404 1.00 102.45 ? 31  SER L OG  1 
ATOM 191  N N   . LEU A 1 32  ? 122.356 104.853 112.855 1.00 95.84  ? 32  LEU L N   1 
ATOM 192  C CA  . LEU A 1 32  ? 123.386 105.724 113.407 1.00 95.84  ? 32  LEU L CA  1 
ATOM 193  C C   . LEU A 1 32  ? 122.942 106.415 114.692 1.00 95.84  ? 32  LEU L C   1 
ATOM 194  O O   . LEU A 1 32  ? 123.530 107.429 115.079 1.00 95.84  ? 32  LEU L O   1 
ATOM 195  C CB  . LEU A 1 32  ? 123.817 106.760 112.370 1.00 95.84  ? 32  LEU L CB  1 
ATOM 196  C CG  . LEU A 1 32  ? 124.717 106.226 111.258 1.00 95.84  ? 32  LEU L CG  1 
ATOM 197  C CD1 . LEU A 1 32  ? 124.990 107.298 110.224 1.00 95.84  ? 32  LEU L CD1 1 
ATOM 198  C CD2 . LEU A 1 32  ? 126.013 105.705 111.841 1.00 95.84  ? 32  LEU L CD2 1 
ATOM 199  N N   . LEU A 1 33  ? 121.917 105.891 115.359 1.00 95.67  ? 33  LEU L N   1 
ATOM 200  C CA  . LEU A 1 33  ? 121.466 106.442 116.638 1.00 95.67  ? 33  LEU L CA  1 
ATOM 201  C C   . LEU A 1 33  ? 122.174 105.740 117.797 1.00 95.67  ? 33  LEU L C   1 
ATOM 202  O O   . LEU A 1 33  ? 121.558 105.172 118.697 1.00 95.67  ? 33  LEU L O   1 
ATOM 203  C CB  . LEU A 1 33  ? 119.951 106.330 116.765 1.00 95.67  ? 33  LEU L CB  1 
ATOM 204  C CG  . LEU A 1 33  ? 119.072 107.401 116.114 1.00 95.67  ? 33  LEU L CG  1 
ATOM 205  C CD1 . LEU A 1 33  ? 119.322 108.754 116.760 1.00 95.67  ? 33  LEU L CD1 1 
ATOM 206  C CD2 . LEU A 1 33  ? 119.267 107.473 114.608 1.00 95.67  ? 33  LEU L CD2 1 
ATOM 207  N N   . PHE A 1 34  ? 123.507 105.788 117.753 1.00 91.47  ? 34  PHE L N   1 
ATOM 208  C CA  . PHE A 1 34  ? 124.306 105.147 118.792 1.00 91.47  ? 34  PHE L CA  1 
ATOM 209  C C   . PHE A 1 34  ? 124.103 105.817 120.145 1.00 91.47  ? 34  PHE L C   1 
ATOM 210  O O   . PHE A 1 34  ? 124.064 105.140 121.178 1.00 91.47  ? 34  PHE L O   1 
ATOM 211  C CB  . PHE A 1 34  ? 125.783 105.166 118.404 1.00 91.47  ? 34  PHE L CB  1 
ATOM 212  C CG  . PHE A 1 34  ? 126.109 104.303 117.222 1.00 91.47  ? 34  PHE L CG  1 
ATOM 213  C CD1 . PHE A 1 34  ? 126.112 102.925 117.335 1.00 91.47  ? 34  PHE L CD1 1 
ATOM 214  C CD2 . PHE A 1 34  ? 126.420 104.870 116.000 1.00 91.47  ? 34  PHE L CD2 1 
ATOM 215  C CE1 . PHE A 1 34  ? 126.414 102.128 116.249 1.00 91.47  ? 34  PHE L CE1 1 
ATOM 216  C CE2 . PHE A 1 34  ? 126.723 104.079 114.912 1.00 91.47  ? 34  PHE L CE2 1 
ATOM 217  C CZ  . PHE A 1 34  ? 126.720 102.707 115.036 1.00 91.47  ? 34  PHE L CZ  1 
ATOM 218  N N   . SER A 1 35  ? 123.983 107.143 120.160 1.00 85.20  ? 35  SER L N   1 
ATOM 219  C CA  . SER A 1 35  ? 123.851 107.871 121.414 1.00 85.20  ? 35  SER L CA  1 
ATOM 220  C C   . SER A 1 35  ? 122.565 107.482 122.131 1.00 85.20  ? 35  SER L C   1 
ATOM 221  O O   . SER A 1 35  ? 121.543 107.203 121.499 1.00 85.20  ? 35  SER L O   1 
ATOM 222  C CB  . SER A 1 35  ? 123.876 109.376 121.156 1.00 85.20  ? 35  SER L CB  1 
ATOM 223  O OG  . SER A 1 35  ? 122.760 109.775 120.382 1.00 85.20  ? 35  SER L OG  1 
ATOM 224  N N   . SER A 1 36  ? 122.627 107.451 123.465 1.00 83.76  ? 36  SER L N   1 
ATOM 225  C CA  . SER A 1 36  ? 121.454 107.085 124.253 1.00 83.76  ? 36  SER L CA  1 
ATOM 226  C C   . SER A 1 36  ? 120.314 108.067 124.021 1.00 83.76  ? 36  SER L C   1 
ATOM 227  O O   . SER A 1 36  ? 119.188 107.665 123.706 1.00 83.76  ? 36  SER L O   1 
ATOM 228  C CB  . SER A 1 36  ? 121.816 107.016 125.735 1.00 83.76  ? 36  SER L CB  1 
ATOM 229  O OG  . SER A 1 36  ? 120.711 106.582 126.504 1.00 83.76  ? 36  SER L OG  1 
ATOM 230  N N   . ASN A 1 37  ? 120.584 109.359 124.173 1.00 83.88  ? 37  ASN L N   1 
ATOM 231  C CA  . ASN A 1 37  ? 119.664 110.371 123.682 1.00 83.88  ? 37  ASN L CA  1 
ATOM 232  C C   . ASN A 1 37  ? 119.772 110.447 122.165 1.00 83.88  ? 37  ASN L C   1 
ATOM 233  O O   . ASN A 1 37  ? 120.814 110.126 121.588 1.00 83.88  ? 37  ASN L O   1 
ATOM 234  C CB  . ASN A 1 37  ? 119.945 111.730 124.325 1.00 83.88  ? 37  ASN L CB  1 
ATOM 235  C CG  . ASN A 1 37  ? 121.383 112.176 124.162 1.00 83.88  ? 37  ASN L CG  1 
ATOM 236  O OD1 . ASN A 1 37  ? 122.192 111.501 123.529 1.00 83.88  ? 37  ASN L OD1 1 
ATOM 237  N ND2 . ASN A 1 37  ? 121.709 113.325 124.737 1.00 83.88  ? 37  ASN L ND2 1 
ATOM 238  N N   . GLN A 1 38  ? 118.688 110.855 121.517 1.00 88.33  ? 38  GLN L N   1 
ATOM 239  C CA  . GLN A 1 38  ? 118.589 110.733 120.065 1.00 88.33  ? 38  GLN L CA  1 
ATOM 240  C C   . GLN A 1 38  ? 119.455 111.794 119.401 1.00 88.33  ? 38  GLN L C   1 
ATOM 241  O O   . GLN A 1 38  ? 118.969 112.857 119.012 1.00 88.33  ? 38  GLN L O   1 
ATOM 242  C CB  . GLN A 1 38  ? 117.135 110.848 119.627 1.00 88.33  ? 38  GLN L CB  1 
ATOM 243  C CG  . GLN A 1 38  ? 116.353 109.552 119.764 1.00 88.33  ? 38  GLN L CG  1 
ATOM 244  C CD  . GLN A 1 38  ? 116.258 109.076 121.200 1.00 88.33  ? 38  GLN L CD  1 
ATOM 245  O OE1 . GLN A 1 38  ? 116.719 107.986 121.536 1.00 88.33  ? 38  GLN L OE1 1 
ATOM 246  N NE2 . GLN A 1 38  ? 115.664 109.898 122.057 1.00 88.33  ? 38  GLN L NE2 1 
ATOM 247  N N   . LYS A 1 39  ? 120.743 111.492 119.246 1.00 84.98  ? 39  LYS L N   1 
ATOM 248  C CA  . LYS A 1 39  ? 121.679 112.379 118.563 1.00 84.98  ? 39  LYS L CA  1 
ATOM 249  C C   . LYS A 1 39  ? 122.417 111.564 117.515 1.00 84.98  ? 39  LYS L C   1 
ATOM 250  O O   . LYS A 1 39  ? 123.011 110.534 117.841 1.00 84.98  ? 39  LYS L O   1 
ATOM 251  C CB  . LYS A 1 39  ? 122.673 113.009 119.542 1.00 84.98  ? 39  LYS L CB  1 
ATOM 252  C CG  . LYS A 1 39  ? 122.049 113.836 120.654 1.00 84.98  ? 39  LYS L CG  1 
ATOM 253  C CD  . LYS A 1 39  ? 121.065 114.860 120.120 1.00 84.98  ? 39  LYS L CD  1 
ATOM 254  C CE  . LYS A 1 39  ? 121.762 115.952 119.335 1.00 84.98  ? 39  LYS L CE  1 
ATOM 255  N NZ  . LYS A 1 39  ? 123.069 116.305 119.939 1.00 84.98  ? 39  LYS L NZ  1 
ATOM 256  N N   . ASN A 1 40  ? 122.384 112.022 116.267 1.00 88.24  ? 40  ASN L N   1 
ATOM 257  C CA  . ASN A 1 40  ? 123.085 111.326 115.201 1.00 88.24  ? 40  ASN L CA  1 
ATOM 258  C C   . ASN A 1 40  ? 124.592 111.522 115.335 1.00 88.24  ? 40  ASN L C   1 
ATOM 259  O O   . ASN A 1 40  ? 125.071 112.422 116.028 1.00 88.24  ? 40  ASN L O   1 
ATOM 260  C CB  . ASN A 1 40  ? 122.613 111.819 113.836 1.00 88.24  ? 40  ASN L CB  1 
ATOM 261  C CG  . ASN A 1 40  ? 121.157 111.515 113.584 1.00 88.24  ? 40  ASN L CG  1 
ATOM 262  O OD1 . ASN A 1 40  ? 120.322 112.416 113.539 1.00 88.24  ? 40  ASN L OD1 1 
ATOM 263  N ND2 . ASN A 1 40  ? 120.841 110.238 113.418 1.00 88.24  ? 40  ASN L ND2 1 
ATOM 264  N N   . TYR A 1 41  ? 125.343 110.657 114.656 1.00 82.46  ? 41  TYR L N   1 
ATOM 265  C CA  . TYR A 1 41  ? 126.798 110.705 114.715 1.00 82.46  ? 41  TYR L CA  1 
ATOM 266  C C   . TYR A 1 41  ? 127.447 110.892 113.350 1.00 82.46  ? 41  TYR L C   1 
ATOM 267  O O   . TYR A 1 41  ? 128.402 110.183 113.022 1.00 82.46  ? 41  TYR L O   1 
ATOM 268  C CB  . TYR A 1 41  ? 127.350 109.436 115.365 1.00 82.46  ? 41  TYR L CB  1 
ATOM 269  C CG  . TYR A 1 41  ? 127.338 109.443 116.874 1.00 82.46  ? 41  TYR L CG  1 
ATOM 270  C CD1 . TYR A 1 41  ? 127.117 110.611 117.581 1.00 82.46  ? 41  TYR L CD1 1 
ATOM 271  C CD2 . TYR A 1 41  ? 127.577 108.284 117.592 1.00 82.46  ? 41  TYR L CD2 1 
ATOM 272  C CE1 . TYR A 1 41  ? 127.118 110.619 118.960 1.00 82.46  ? 41  TYR L CE1 1 
ATOM 273  C CE2 . TYR A 1 41  ? 127.584 108.285 118.971 1.00 82.46  ? 41  TYR L CE2 1 
ATOM 274  C CZ  . TYR A 1 41  ? 127.353 109.457 119.649 1.00 82.46  ? 41  TYR L CZ  1 
ATOM 275  O OH  . TYR A 1 41  ? 127.355 109.468 121.023 1.00 82.46  ? 41  TYR L OH  1 
ATOM 276  N N   . LEU A 1 42  ? 126.957 111.826 112.547 1.00 80.83  ? 42  LEU L N   1 
ATOM 277  C CA  . LEU A 1 42  ? 127.601 112.126 111.277 1.00 80.83  ? 42  LEU L CA  1 
ATOM 278  C C   . LEU A 1 42  ? 128.361 113.443 111.335 1.00 80.83  ? 42  LEU L C   1 
ATOM 279  O O   . LEU A 1 42  ? 128.076 114.325 112.147 1.00 80.83  ? 42  LEU L O   1 
ATOM 280  C CB  . LEU A 1 42  ? 126.594 112.183 110.132 1.00 80.83  ? 42  LEU L CB  1 
ATOM 281  C CG  . LEU A 1 42  ? 126.128 110.846 109.573 1.00 80.83  ? 42  LEU L CG  1 
ATOM 282  C CD1 . LEU A 1 42  ? 125.035 111.100 108.583 1.00 80.83  ? 42  LEU L CD1 1 
ATOM 283  C CD2 . LEU A 1 42  ? 127.274 110.106 108.917 1.00 80.83  ? 42  LEU L CD2 1 
ATOM 284  N N   . ALA A 1 43  ? 129.344 113.557 110.449 1.00 82.03  ? 43  ALA L N   1 
ATOM 285  C CA  . ALA A 1 43  ? 130.087 114.793 110.262 1.00 82.03  ? 43  ALA L CA  1 
ATOM 286  C C   . ALA A 1 43  ? 130.350 114.960 108.776 1.00 82.03  ? 43  ALA L C   1 
ATOM 287  O O   . ALA A 1 43  ? 130.676 113.986 108.092 1.00 82.03  ? 43  ALA L O   1 
ATOM 288  C CB  . ALA A 1 43  ? 131.401 114.783 111.045 1.00 82.03  ? 43  ALA L CB  1 
ATOM 289  N N   . TRP A 1 44  ? 130.200 116.182 108.279 1.00 87.06  ? 44  TRP L N   1 
ATOM 290  C CA  . TRP A 1 44  ? 130.375 116.477 106.864 1.00 87.06  ? 44  TRP L CA  1 
ATOM 291  C C   . TRP A 1 44  ? 131.660 117.270 106.669 1.00 87.06  ? 44  TRP L C   1 
ATOM 292  O O   . TRP A 1 44  ? 131.813 118.360 107.228 1.00 87.06  ? 44  TRP L O   1 
ATOM 293  C CB  . TRP A 1 44  ? 129.178 117.254 106.320 1.00 87.06  ? 44  TRP L CB  1 
ATOM 294  C CG  . TRP A 1 44  ? 127.972 116.406 106.108 1.00 87.06  ? 44  TRP L CG  1 
ATOM 295  C CD1 . TRP A 1 44  ? 126.978 116.160 107.004 1.00 87.06  ? 44  TRP L CD1 1 
ATOM 296  C CD2 . TRP A 1 44  ? 127.631 115.685 104.922 1.00 87.06  ? 44  TRP L CD2 1 
ATOM 297  N NE1 . TRP A 1 44  ? 126.036 115.331 106.450 1.00 87.06  ? 44  TRP L NE1 1 
ATOM 298  C CE2 . TRP A 1 44  ? 126.415 115.025 105.171 1.00 87.06  ? 44  TRP L CE2 1 
ATOM 299  C CE3 . TRP A 1 44  ? 128.235 115.534 103.672 1.00 87.06  ? 44  TRP L CE3 1 
ATOM 300  C CZ2 . TRP A 1 44  ? 125.793 114.228 104.218 1.00 87.06  ? 44  TRP L CZ2 1 
ATOM 301  C CZ3 . TRP A 1 44  ? 127.617 114.743 102.730 1.00 87.06  ? 44  TRP L CZ3 1 
ATOM 302  C CH2 . TRP A 1 44  ? 126.409 114.099 103.006 1.00 87.06  ? 44  TRP L CH2 1 
ATOM 303  N N   . TYR A 1 45  ? 132.573 116.728 105.872 1.00 84.21  ? 45  TYR L N   1 
ATOM 304  C CA  . TYR A 1 45  ? 133.846 117.367 105.579 1.00 84.21  ? 45  TYR L CA  1 
ATOM 305  C C   . TYR A 1 45  ? 133.910 117.724 104.103 1.00 84.21  ? 45  TYR L C   1 
ATOM 306  O O   . TYR A 1 45  ? 133.453 116.956 103.251 1.00 84.21  ? 45  TYR L O   1 
ATOM 307  C CB  . TYR A 1 45  ? 135.020 116.452 105.930 1.00 84.21  ? 45  TYR L CB  1 
ATOM 308  C CG  . TYR A 1 45  ? 135.122 116.097 107.391 1.00 84.21  ? 45  TYR L CG  1 
ATOM 309  C CD1 . TYR A 1 45  ? 134.373 115.064 107.925 1.00 84.21  ? 45  TYR L CD1 1 
ATOM 310  C CD2 . TYR A 1 45  ? 135.974 116.790 108.234 1.00 84.21  ? 45  TYR L CD2 1 
ATOM 311  C CE1 . TYR A 1 45  ? 134.463 114.735 109.256 1.00 84.21  ? 45  TYR L CE1 1 
ATOM 312  C CE2 . TYR A 1 45  ? 136.072 116.467 109.568 1.00 84.21  ? 45  TYR L CE2 1 
ATOM 313  C CZ  . TYR A 1 45  ? 135.313 115.437 110.073 1.00 84.21  ? 45  TYR L CZ  1 
ATOM 314  O OH  . TYR A 1 45  ? 135.404 115.108 111.404 1.00 84.21  ? 45  TYR L OH  1 
ATOM 315  N N   . GLN A 1 46  ? 134.476 118.889 103.802 1.00 88.61  ? 46  GLN L N   1 
ATOM 316  C CA  . GLN A 1 46  ? 134.728 119.302 102.430 1.00 88.61  ? 46  GLN L CA  1 
ATOM 317  C C   . GLN A 1 46  ? 136.225 119.497 102.246 1.00 88.61  ? 46  GLN L C   1 
ATOM 318  O O   . GLN A 1 46  ? 136.881 120.120 103.086 1.00 88.61  ? 46  GLN L O   1 
ATOM 319  C CB  . GLN A 1 46  ? 133.956 120.579 102.075 1.00 88.61  ? 46  GLN L CB  1 
ATOM 320  C CG  . GLN A 1 46  ? 134.470 121.858 102.708 1.00 88.61  ? 46  GLN L CG  1 
ATOM 321  C CD  . GLN A 1 46  ? 134.163 123.079 101.868 1.00 88.61  ? 46  GLN L CD  1 
ATOM 322  O OE1 . GLN A 1 46  ? 133.033 123.270 101.423 1.00 88.61  ? 46  GLN L OE1 1 
ATOM 323  N NE2 . GLN A 1 46  ? 135.171 123.911 101.642 1.00 88.61  ? 46  GLN L NE2 1 
ATOM 324  N N   . GLN A 1 47  ? 136.766 118.943 101.165 1.00 94.04  ? 47  GLN L N   1 
ATOM 325  C CA  . GLN A 1 47  ? 138.200 118.972 100.908 1.00 94.04  ? 47  GLN L CA  1 
ATOM 326  C C   . GLN A 1 47  ? 138.463 119.674 99.587  1.00 94.04  ? 47  GLN L C   1 
ATOM 327  O O   . GLN A 1 47  ? 138.006 119.215 98.536  1.00 94.04  ? 47  GLN L O   1 
ATOM 328  C CB  . GLN A 1 47  ? 138.787 117.561 100.876 1.00 94.04  ? 47  GLN L CB  1 
ATOM 329  C CG  . GLN A 1 47  ? 140.196 117.507 100.317 1.00 94.04  ? 47  GLN L CG  1 
ATOM 330  C CD  . GLN A 1 47  ? 140.776 116.110 100.320 1.00 94.04  ? 47  GLN L CD  1 
ATOM 331  O OE1 . GLN A 1 47  ? 140.044 115.122 100.325 1.00 94.04  ? 47  GLN L OE1 1 
ATOM 332  N NE2 . GLN A 1 47  ? 142.099 116.019 100.319 1.00 94.04  ? 47  GLN L NE2 1 
ATOM 333  N N   . ASN A 1 48  ? 139.201 120.777 99.644  1.00 96.75  ? 48  ASN L N   1 
ATOM 334  C CA  . ASN A 1 48  ? 139.680 121.417 98.437  1.00 96.75  ? 48  ASN L CA  1 
ATOM 335  C C   . ASN A 1 48  ? 140.794 120.574 97.821  1.00 96.75  ? 48  ASN L C   1 
ATOM 336  O O   . ASN A 1 48  ? 141.467 119.814 98.521  1.00 96.75  ? 48  ASN L O   1 
ATOM 337  C CB  . ASN A 1 48  ? 140.177 122.825 98.748  1.00 96.75  ? 48  ASN L CB  1 
ATOM 338  C CG  . ASN A 1 48  ? 139.048 123.828 98.856  1.00 96.75  ? 48  ASN L CG  1 
ATOM 339  O OD1 . ASN A 1 48  ? 139.000 124.628 99.788  1.00 96.75  ? 48  ASN L OD1 1 
ATOM 340  N ND2 . ASN A 1 48  ? 138.133 123.791 97.896  1.00 96.75  ? 48  ASN L ND2 1 
ATOM 341  N N   . PRO A 1 49  ? 141.008 120.686 96.508  1.00 98.21  ? 49  PRO L N   1 
ATOM 342  C CA  . PRO A 1 49  ? 142.026 119.841 95.863  1.00 98.21  ? 49  PRO L CA  1 
ATOM 343  C C   . PRO A 1 49  ? 143.439 120.090 96.363  1.00 98.21  ? 49  PRO L C   1 
ATOM 344  O O   . PRO A 1 49  ? 144.314 119.246 96.138  1.00 98.21  ? 49  PRO L O   1 
ATOM 345  C CB  . PRO A 1 49  ? 141.889 120.197 94.376  1.00 98.21  ? 49  PRO L CB  1 
ATOM 346  C CG  . PRO A 1 49  ? 141.220 121.527 94.356  1.00 98.21  ? 49  PRO L CG  1 
ATOM 347  C CD  . PRO A 1 49  ? 140.310 121.548 95.540  1.00 98.21  ? 49  PRO L CD  1 
ATOM 348  N N   . GLY A 1 50  ? 143.692 121.212 97.032  1.00 99.27  ? 50  GLY L N   1 
ATOM 349  C CA  . GLY A 1 50  ? 145.040 121.555 97.440  1.00 99.27  ? 50  GLY L CA  1 
ATOM 350  C C   . GLY A 1 50  ? 145.460 121.059 98.810  1.00 99.27  ? 50  GLY L C   1 
ATOM 351  O O   . GLY A 1 50  ? 146.499 120.406 98.938  1.00 99.27  ? 50  GLY L O   1 
ATOM 352  N N   . GLN A 1 51  ? 144.668 121.351 99.841  1.00 96.35  ? 51  GLN L N   1 
ATOM 353  C CA  . GLN A 1 51  ? 145.114 121.112 101.210 1.00 96.35  ? 51  GLN L CA  1 
ATOM 354  C C   . GLN A 1 51  ? 144.135 120.258 102.007 1.00 96.35  ? 51  GLN L C   1 
ATOM 355  O O   . GLN A 1 51  ? 143.178 119.709 101.452 1.00 96.35  ? 51  GLN L O   1 
ATOM 356  C CB  . GLN A 1 51  ? 145.351 122.442 101.934 1.00 96.35  ? 51  GLN L CB  1 
ATOM 357  C CG  . GLN A 1 51  ? 144.092 123.218 102.327 1.00 96.35  ? 51  GLN L CG  1 
ATOM 358  C CD  . GLN A 1 51  ? 143.176 123.523 101.160 1.00 96.35  ? 51  GLN L CD  1 
ATOM 359  O OE1 . GLN A 1 51  ? 143.626 123.684 100.026 1.00 96.35  ? 51  GLN L OE1 1 
ATOM 360  N NE2 . GLN A 1 51  ? 141.881 123.606 101.434 1.00 96.35  ? 51  GLN L NE2 1 
ATOM 361  N N   . SER A 1 52  ? 144.378 120.145 103.312 1.00 95.89  ? 52  SER L N   1 
ATOM 362  C CA  . SER A 1 52  ? 143.567 119.297 104.168 1.00 95.89  ? 52  SER L CA  1 
ATOM 363  C C   . SER A 1 52  ? 142.143 119.837 104.276 1.00 95.89  ? 52  SER L C   1 
ATOM 364  O O   . SER A 1 52  ? 141.924 121.050 104.231 1.00 95.89  ? 52  SER L O   1 
ATOM 365  C CB  . SER A 1 52  ? 144.186 119.202 105.558 1.00 95.89  ? 52  SER L CB  1 
ATOM 366  O OG  . SER A 1 52  ? 144.450 120.491 106.083 1.00 95.89  ? 52  SER L OG  1 
ATOM 367  N N   . PRO A 1 53  ? 141.158 118.956 104.423 1.00 90.15  ? 53  PRO L N   1 
ATOM 368  C CA  . PRO A 1 53  ? 139.765 119.404 104.501 1.00 90.15  ? 53  PRO L CA  1 
ATOM 369  C C   . PRO A 1 53  ? 139.440 120.042 105.842 1.00 90.15  ? 53  PRO L C   1 
ATOM 370  O O   . PRO A 1 53  ? 140.251 120.096 106.767 1.00 90.15  ? 53  PRO L O   1 
ATOM 371  C CB  . PRO A 1 53  ? 138.968 118.115 104.295 1.00 90.15  ? 53  PRO L CB  1 
ATOM 372  C CG  . PRO A 1 53  ? 139.868 117.054 104.729 1.00 90.15  ? 53  PRO L CG  1 
ATOM 373  C CD  . PRO A 1 53  ? 141.257 117.490 104.375 1.00 90.15  ? 53  PRO L CD  1 
ATOM 374  N N   . LYS A 1 54  ? 138.206 120.529 105.927 1.00 86.63  ? 54  LYS L N   1 
ATOM 375  C CA  . LYS A 1 54  ? 137.699 121.225 107.098 1.00 86.63  ? 54  LYS L CA  1 
ATOM 376  C C   . LYS A 1 54  ? 136.391 120.587 107.535 1.00 86.63  ? 54  LYS L C   1 
ATOM 377  O O   . LYS A 1 54  ? 135.668 120.002 106.725 1.00 86.63  ? 54  LYS L O   1 
ATOM 378  C CB  . LYS A 1 54  ? 137.477 122.708 106.801 1.00 86.63  ? 54  LYS L CB  1 
ATOM 379  C CG  . LYS A 1 54  ? 138.746 123.463 106.466 1.00 86.63  ? 54  LYS L CG  1 
ATOM 380  C CD  . LYS A 1 54  ? 138.460 124.933 106.246 1.00 86.63  ? 54  LYS L CD  1 
ATOM 381  C CE  . LYS A 1 54  ? 137.692 125.137 104.953 1.00 86.63  ? 54  LYS L CE  1 
ATOM 382  N NZ  . LYS A 1 54  ? 138.514 124.772 103.765 1.00 86.63  ? 54  LYS L NZ  1 
ATOM 383  N N   . LEU A 1 55  ? 136.092 120.700 108.824 1.00 79.95  ? 55  LEU L N   1 
ATOM 384  C CA  . LEU A 1 55  ? 134.831 120.199 109.347 1.00 79.95  ? 55  LEU L CA  1 
ATOM 385  C C   . LEU A 1 55  ? 133.741 121.242 109.151 1.00 79.95  ? 55  LEU L C   1 
ATOM 386  O O   . LEU A 1 55  ? 133.964 122.439 109.348 1.00 79.95  ? 55  LEU L O   1 
ATOM 387  C CB  . LEU A 1 55  ? 134.970 119.846 110.827 1.00 79.95  ? 55  LEU L CB  1 
ATOM 388  C CG  . LEU A 1 55  ? 133.830 119.063 111.479 1.00 79.95  ? 55  LEU L CG  1 
ATOM 389  C CD1 . LEU A 1 55  ? 134.389 118.189 112.572 1.00 79.95  ? 55  LEU L CD1 1 
ATOM 390  C CD2 . LEU A 1 55  ? 132.779 119.985 112.048 1.00 79.95  ? 55  LEU L CD2 1 
ATOM 391  N N   . LEU A 1 56  ? 132.554 120.783 108.757 1.00 83.39  ? 56  LEU L N   1 
ATOM 392  C CA  . LEU A 1 56  ? 131.436 121.682 108.495 1.00 83.39  ? 56  LEU L CA  1 
ATOM 393  C C   . LEU A 1 56  ? 130.288 121.476 109.472 1.00 83.39  ? 56  LEU L C   1 
ATOM 394  O O   . LEU A 1 56  ? 129.888 122.427 110.150 1.00 83.39  ? 56  LEU L O   1 
ATOM 395  C CB  . LEU A 1 56  ? 130.950 121.501 107.052 1.00 83.39  ? 56  LEU L CB  1 
ATOM 396  C CG  . LEU A 1 56  ? 131.895 122.025 105.974 1.00 83.39  ? 56  LEU L CG  1 
ATOM 397  C CD1 . LEU A 1 56  ? 131.262 121.889 104.601 1.00 83.39  ? 56  LEU L CD1 1 
ATOM 398  C CD2 . LEU A 1 56  ? 132.264 123.467 106.258 1.00 83.39  ? 56  LEU L CD2 1 
ATOM 399  N N   . ILE A 1 57  ? 129.744 120.267 109.569 1.00 78.12  ? 57  ILE L N   1 
ATOM 400  C CA  . ILE A 1 57  ? 128.581 119.993 110.404 1.00 78.12  ? 57  ILE L CA  1 
ATOM 401  C C   . ILE A 1 57  ? 128.844 118.722 111.194 1.00 78.12  ? 57  ILE L C   1 
ATOM 402  O O   . ILE A 1 57  ? 129.311 117.728 110.632 1.00 78.12  ? 57  ILE L O   1 
ATOM 403  C CB  . ILE A 1 57  ? 127.300 119.842 109.561 1.00 78.12  ? 57  ILE L CB  1 
ATOM 404  C CG1 . ILE A 1 57  ? 126.978 121.143 108.832 1.00 78.12  ? 57  ILE L CG1 1 
ATOM 405  C CG2 . ILE A 1 57  ? 126.131 119.427 110.429 1.00 78.12  ? 57  ILE L CG2 1 
ATOM 406  C CD1 . ILE A 1 57  ? 125.895 120.994 107.795 1.00 78.12  ? 57  ILE L CD1 1 
ATOM 407  N N   . TYR A 1 58  ? 128.554 118.749 112.492 1.00 75.34  ? 58  TYR L N   1 
ATOM 408  C CA  . TYR A 1 58  ? 128.552 117.543 113.305 1.00 75.34  ? 58  TYR L CA  1 
ATOM 409  C C   . TYR A 1 58  ? 127.187 117.398 113.960 1.00 75.34  ? 58  TYR L C   1 
ATOM 410  O O   . TYR A 1 58  ? 126.403 118.348 114.019 1.00 75.34  ? 58  TYR L O   1 
ATOM 411  C CB  . TYR A 1 58  ? 129.667 117.549 114.358 1.00 75.34  ? 58  TYR L CB  1 
ATOM 412  C CG  . TYR A 1 58  ? 129.771 118.806 115.183 1.00 75.34  ? 58  TYR L CG  1 
ATOM 413  C CD1 . TYR A 1 58  ? 128.985 118.986 116.308 1.00 75.34  ? 58  TYR L CD1 1 
ATOM 414  C CD2 . TYR A 1 58  ? 130.673 119.803 114.852 1.00 75.34  ? 58  TYR L CD2 1 
ATOM 415  C CE1 . TYR A 1 58  ? 129.082 120.128 117.071 1.00 75.34  ? 58  TYR L CE1 1 
ATOM 416  C CE2 . TYR A 1 58  ? 130.778 120.949 115.609 1.00 75.34  ? 58  TYR L CE2 1 
ATOM 417  C CZ  . TYR A 1 58  ? 129.980 121.106 116.718 1.00 75.34  ? 58  TYR L CZ  1 
ATOM 418  O OH  . TYR A 1 58  ? 130.078 122.247 117.479 1.00 75.34  ? 58  TYR L OH  1 
ATOM 419  N N   . TRP A 1 59  ? 126.901 116.184 114.431 1.00 74.20  ? 59  TRP L N   1 
ATOM 420  C CA  . TRP A 1 59  ? 125.579 115.754 114.883 1.00 74.20  ? 59  TRP L CA  1 
ATOM 421  C C   . TRP A 1 59  ? 124.549 115.774 113.762 1.00 74.20  ? 59  TRP L C   1 
ATOM 422  O O   . TRP A 1 59  ? 123.354 115.599 114.024 1.00 74.20  ? 59  TRP L O   1 
ATOM 423  C CB  . TRP A 1 59  ? 125.063 116.599 116.057 1.00 74.20  ? 59  TRP L CB  1 
ATOM 424  C CG  . TRP A 1 59  ? 126.017 116.779 117.200 1.00 74.20  ? 59  TRP L CG  1 
ATOM 425  C CD1 . TRP A 1 59  ? 126.248 117.935 117.883 1.00 74.20  ? 59  TRP L CD1 1 
ATOM 426  C CD2 . TRP A 1 59  ? 126.827 115.777 117.830 1.00 74.20  ? 59  TRP L CD2 1 
ATOM 427  N NE1 . TRP A 1 59  ? 127.170 117.726 118.875 1.00 74.20  ? 59  TRP L NE1 1 
ATOM 428  C CE2 . TRP A 1 59  ? 127.539 116.408 118.866 1.00 74.20  ? 59  TRP L CE2 1 
ATOM 429  C CE3 . TRP A 1 59  ? 127.025 114.414 117.615 1.00 74.20  ? 59  TRP L CE3 1 
ATOM 430  C CZ2 . TRP A 1 59  ? 128.432 115.725 119.679 1.00 74.20  ? 59  TRP L CZ2 1 
ATOM 431  C CZ3 . TRP A 1 59  ? 127.916 113.742 118.423 1.00 74.20  ? 59  TRP L CZ3 1 
ATOM 432  C CH2 . TRP A 1 59  ? 128.606 114.394 119.441 1.00 74.20  ? 59  TRP L CH2 1 
ATOM 433  N N   . ALA A 1 60  ? 124.983 116.007 112.523 1.00 77.84  ? 60  ALA L N   1 
ATOM 434  C CA  . ALA A 1 60  ? 124.181 116.066 111.305 1.00 77.84  ? 60  ALA L CA  1 
ATOM 435  C C   . ALA A 1 60  ? 123.252 117.271 111.258 1.00 77.84  ? 60  ALA L C   1 
ATOM 436  O O   . ALA A 1 60  ? 122.580 117.469 110.241 1.00 77.84  ? 60  ALA L O   1 
ATOM 437  C CB  . ALA A 1 60  ? 123.350 114.794 111.084 1.00 77.84  ? 60  ALA L CB  1 
ATOM 438  N N   . SER A 1 61  ? 123.188 118.084 112.313 1.00 80.08  ? 61  SER L N   1 
ATOM 439  C CA  . SER A 1 61  ? 122.334 119.262 112.300 1.00 80.08  ? 61  SER L CA  1 
ATOM 440  C C   . SER A 1 61  ? 122.938 120.479 112.988 1.00 80.08  ? 61  SER L C   1 
ATOM 441  O O   . SER A 1 61  ? 122.263 121.509 113.069 1.00 80.08  ? 61  SER L O   1 
ATOM 442  C CB  . SER A 1 61  ? 120.979 118.941 112.950 1.00 80.08  ? 61  SER L CB  1 
ATOM 443  O OG  . SER A 1 61  ? 121.146 118.531 114.295 1.00 80.08  ? 61  SER L OG  1 
ATOM 444  N N   . THR A 1 62  ? 124.171 120.405 113.478 1.00 80.37  ? 62  THR L N   1 
ATOM 445  C CA  . THR A 1 62  ? 124.791 121.500 114.211 1.00 80.37  ? 62  THR L CA  1 
ATOM 446  C C   . THR A 1 62  ? 125.979 122.028 113.423 1.00 80.37  ? 62  THR L C   1 
ATOM 447  O O   . THR A 1 62  ? 126.880 121.263 113.065 1.00 80.37  ? 62  THR L O   1 
ATOM 448  C CB  . THR A 1 62  ? 125.242 121.048 115.602 1.00 80.37  ? 62  THR L CB  1 
ATOM 449  O OG1 . THR A 1 62  ? 124.093 120.787 116.417 1.00 80.37  ? 62  THR L OG1 1 
ATOM 450  C CG2 . THR A 1 62  ? 126.087 122.122 116.263 1.00 80.37  ? 62  THR L CG2 1 
ATOM 451  N N   . ARG A 1 63  ? 125.979 123.330 113.158 1.00 88.94  ? 63  ARG L N   1 
ATOM 452  C CA  . ARG A 1 63  ? 127.070 123.939 112.417 1.00 88.94  ? 63  ARG L CA  1 
ATOM 453  C C   . ARG A 1 63  ? 128.305 124.075 113.303 1.00 88.94  ? 63  ARG L C   1 
ATOM 454  O O   . ARG A 1 63  ? 128.219 124.139 114.532 1.00 88.94  ? 63  ARG L O   1 
ATOM 455  C CB  . ARG A 1 63  ? 126.657 125.309 111.886 1.00 88.94  ? 63  ARG L CB  1 
ATOM 456  C CG  . ARG A 1 63  ? 127.262 125.666 110.544 1.00 88.94  ? 63  ARG L CG  1 
ATOM 457  C CD  . ARG A 1 63  ? 126.463 126.778 109.898 1.00 88.94  ? 63  ARG L CD  1 
ATOM 458  N NE  . ARG A 1 63  ? 125.074 126.385 109.700 1.00 88.94  ? 63  ARG L NE  1 
ATOM 459  C CZ  . ARG A 1 63  ? 124.037 127.021 110.226 1.00 88.94  ? 63  ARG L CZ  1 
ATOM 460  N NH1 . ARG A 1 63  ? 124.197 128.094 110.983 1.00 88.94  ? 63  ARG L NH1 1 
ATOM 461  N NH2 . ARG A 1 63  ? 122.809 126.567 109.993 1.00 88.94  ? 63  ARG L NH2 1 
ATOM 462  N N   . GLU A 1 64  ? 129.466 124.121 112.661 1.00 90.29  ? 64  GLU L N   1 
ATOM 463  C CA  . GLU A 1 64  ? 130.735 124.275 113.356 1.00 90.29  ? 64  GLU L CA  1 
ATOM 464  C C   . GLU A 1 64  ? 131.129 125.745 113.365 1.00 90.29  ? 64  GLU L C   1 
ATOM 465  O O   . GLU A 1 64  ? 130.827 126.482 112.422 1.00 90.29  ? 64  GLU L O   1 
ATOM 466  C CB  . GLU A 1 64  ? 131.820 123.425 112.693 1.00 90.29  ? 64  GLU L CB  1 
ATOM 467  C CG  . GLU A 1 64  ? 133.113 123.298 113.486 1.00 90.29  ? 64  GLU L CG  1 
ATOM 468  C CD  . GLU A 1 64  ? 134.095 124.408 113.195 1.00 90.29  ? 64  GLU L CD  1 
ATOM 469  O OE1 . GLU A 1 64  ? 134.079 124.928 112.061 1.00 90.29  ? 64  GLU L OE1 1 
ATOM 470  O OE2 . GLU A 1 64  ? 134.887 124.757 114.095 1.00 90.29  ? 64  GLU L OE2 1 
ATOM 471  N N   . SER A 1 65  ? 131.791 126.169 114.440 1.00 96.04  ? 65  SER L N   1 
ATOM 472  C CA  . SER A 1 65  ? 132.113 127.579 114.625 1.00 96.04  ? 65  SER L CA  1 
ATOM 473  C C   . SER A 1 65  ? 133.006 128.091 113.502 1.00 96.04  ? 65  SER L C   1 
ATOM 474  O O   . SER A 1 65  ? 133.974 127.434 113.110 1.00 96.04  ? 65  SER L O   1 
ATOM 475  C CB  . SER A 1 65  ? 132.796 127.788 115.976 1.00 96.04  ? 65  SER L CB  1 
ATOM 476  O OG  . SER A 1 65  ? 133.236 129.126 116.122 1.00 96.04  ? 65  SER L OG  1 
ATOM 477  N N   . GLY A 1 66  ? 132.689 129.279 112.997 1.00 100.00 ? 66  GLY L N   1 
ATOM 478  C CA  . GLY A 1 66  ? 133.442 129.852 111.902 1.00 100.00 ? 66  GLY L CA  1 
ATOM 479  C C   . GLY A 1 66  ? 133.073 129.329 110.535 1.00 100.00 ? 66  GLY L C   1 
ATOM 480  O O   . GLY A 1 66  ? 133.918 129.336 109.632 1.00 100.00 ? 66  GLY L O   1 
ATOM 481  N N   . VAL A 1 67  ? 131.839 128.871 110.351 1.00 97.84  ? 67  VAL L N   1 
ATOM 482  C CA  . VAL A 1 67  ? 131.382 128.343 109.069 1.00 97.84  ? 67  VAL L CA  1 
ATOM 483  C C   . VAL A 1 67  ? 130.174 129.150 108.610 1.00 97.84  ? 67  VAL L C   1 
ATOM 484  O O   . VAL A 1 67  ? 129.270 129.420 109.414 1.00 97.84  ? 67  VAL L O   1 
ATOM 485  C CB  . VAL A 1 67  ? 131.051 126.846 109.174 1.00 97.84  ? 67  VAL L CB  1 
ATOM 486  C CG1 . VAL A 1 67  ? 130.476 126.329 107.870 1.00 97.84  ? 67  VAL L CG1 1 
ATOM 487  C CG2 . VAL A 1 67  ? 132.296 126.061 109.547 1.00 97.84  ? 67  VAL L CG2 1 
ATOM 488  N N   . PRO A 1 68  ? 130.117 129.558 107.344 1.00 100.23 ? 68  PRO L N   1 
ATOM 489  C CA  . PRO A 1 68  ? 128.983 130.363 106.875 1.00 100.23 ? 68  PRO L CA  1 
ATOM 490  C C   . PRO A 1 68  ? 127.674 129.590 106.941 1.00 100.23 ? 68  PRO L C   1 
ATOM 491  O O   . PRO A 1 68  ? 127.642 128.358 106.975 1.00 100.23 ? 68  PRO L O   1 
ATOM 492  C CB  . PRO A 1 68  ? 129.358 130.705 105.428 1.00 100.23 ? 68  PRO L CB  1 
ATOM 493  C CG  . PRO A 1 68  ? 130.448 129.750 105.062 1.00 100.23 ? 68  PRO L CG  1 
ATOM 494  C CD  . PRO A 1 68  ? 131.170 129.432 106.324 1.00 100.23 ? 68  PRO L CD  1 
ATOM 495  N N   . ASP A 1 69  ? 126.576 130.347 106.961 1.00 102.25 ? 69  ASP L N   1 
ATOM 496  C CA  . ASP A 1 69  ? 125.254 129.795 107.232 1.00 102.25 ? 69  ASP L CA  1 
ATOM 497  C C   . ASP A 1 69  ? 124.691 128.978 106.074 1.00 102.25 ? 69  ASP L C   1 
ATOM 498  O O   . ASP A 1 69  ? 123.663 128.317 106.253 1.00 102.25 ? 69  ASP L O   1 
ATOM 499  C CB  . ASP A 1 69  ? 124.298 130.935 107.600 1.00 102.25 ? 69  ASP L CB  1 
ATOM 500  C CG  . ASP A 1 69  ? 122.911 130.445 107.973 1.00 102.25 ? 69  ASP L CG  1 
ATOM 501  O OD1 . ASP A 1 69  ? 122.692 130.129 109.161 1.00 102.25 ? 69  ASP L OD1 1 
ATOM 502  O OD2 . ASP A 1 69  ? 122.042 130.369 107.079 1.00 102.25 ? 69  ASP L OD2 1 
ATOM 503  N N   . ARG A 1 70  ? 125.339 128.987 104.906 1.00 104.90 ? 70  ARG L N   1 
ATOM 504  C CA  . ARG A 1 70  ? 124.817 128.252 103.756 1.00 104.90 ? 70  ARG L CA  1 
ATOM 505  C C   . ARG A 1 70  ? 124.638 126.775 104.085 1.00 104.90 ? 70  ARG L C   1 
ATOM 506  O O   . ARG A 1 70  ? 123.629 126.158 103.729 1.00 104.90 ? 70  ARG L O   1 
ATOM 507  C CB  . ARG A 1 70  ? 125.753 128.403 102.554 1.00 104.90 ? 70  ARG L CB  1 
ATOM 508  C CG  . ARG A 1 70  ? 125.691 129.731 101.824 1.00 104.90 ? 70  ARG L CG  1 
ATOM 509  C CD  . ARG A 1 70  ? 126.558 130.756 102.523 1.00 104.90 ? 70  ARG L CD  1 
ATOM 510  N NE  . ARG A 1 70  ? 127.935 130.285 102.613 1.00 104.90 ? 70  ARG L NE  1 
ATOM 511  C CZ  . ARG A 1 70  ? 128.841 130.420 101.655 1.00 104.90 ? 70  ARG L CZ  1 
ATOM 512  N NH1 . ARG A 1 70  ? 128.560 131.034 100.521 1.00 104.90 ? 70  ARG L NH1 1 
ATOM 513  N NH2 . ARG A 1 70  ? 130.060 129.923 101.840 1.00 104.90 ? 70  ARG L NH2 1 
ATOM 514  N N   . PHE A 1 71  ? 125.617 126.194 104.771 1.00 100.30 ? 71  PHE L N   1 
ATOM 515  C CA  . PHE A 1 71  ? 125.610 124.763 105.030 1.00 100.30 ? 71  PHE L CA  1 
ATOM 516  C C   . PHE A 1 71  ? 124.617 124.420 106.132 1.00 100.30 ? 71  PHE L C   1 
ATOM 517  O O   . PHE A 1 71  ? 124.796 124.812 107.289 1.00 100.30 ? 71  PHE L O   1 
ATOM 518  C CB  . PHE A 1 71  ? 127.009 124.302 105.423 1.00 100.30 ? 71  PHE L CB  1 
ATOM 519  C CG  . PHE A 1 71  ? 128.059 124.636 104.410 1.00 100.30 ? 71  PHE L CG  1 
ATOM 520  C CD1 . PHE A 1 71  ? 128.057 124.038 103.166 1.00 100.30 ? 71  PHE L CD1 1 
ATOM 521  C CD2 . PHE A 1 71  ? 129.042 125.564 104.699 1.00 100.30 ? 71  PHE L CD2 1 
ATOM 522  C CE1 . PHE A 1 71  ? 129.026 124.349 102.237 1.00 100.30 ? 71  PHE L CE1 1 
ATOM 523  C CE2 . PHE A 1 71  ? 130.009 125.881 103.772 1.00 100.30 ? 71  PHE L CE2 1 
ATOM 524  C CZ  . PHE A 1 71  ? 130.001 125.274 102.539 1.00 100.30 ? 71  PHE L CZ  1 
ATOM 525  N N   . THR A 1 72  ? 123.568 123.685 105.771 1.00 100.01 ? 72  THR L N   1 
ATOM 526  C CA  . THR A 1 72  ? 122.601 123.175 106.733 1.00 100.01 ? 72  THR L CA  1 
ATOM 527  C C   . THR A 1 72  ? 122.281 121.734 106.372 1.00 100.01 ? 72  THR L C   1 
ATOM 528  O O   . THR A 1 72  ? 122.344 121.356 105.199 1.00 100.01 ? 72  THR L O   1 
ATOM 529  C CB  . THR A 1 72  ? 121.314 124.009 106.754 1.00 100.01 ? 72  THR L CB  1 
ATOM 530  O OG1 . THR A 1 72  ? 120.690 123.959 105.466 1.00 100.01 ? 72  THR L OG1 1 
ATOM 531  C CG2 . THR A 1 72  ? 121.603 125.457 107.116 1.00 100.01 ? 72  THR L CG2 1 
ATOM 532  N N   . GLY A 1 73  ? 121.933 120.934 107.378 1.00 96.11  ? 73  GLY L N   1 
ATOM 533  C CA  . GLY A 1 73  ? 121.635 119.536 107.155 1.00 96.11  ? 73  GLY L CA  1 
ATOM 534  C C   . GLY A 1 73  ? 120.524 119.055 108.066 1.00 96.11  ? 73  GLY L C   1 
ATOM 535  O O   . GLY A 1 73  ? 120.276 119.616 109.135 1.00 96.11  ? 73  GLY L O   1 
ATOM 536  N N   . SER A 1 74  ? 119.856 117.996 107.617 1.00 101.41 ? 74  SER L N   1 
ATOM 537  C CA  . SER A 1 74  ? 118.797 117.351 108.378 1.00 101.41 ? 74  SER L CA  1 
ATOM 538  C C   . SER A 1 74  ? 119.112 115.870 108.505 1.00 101.41 ? 74  SER L C   1 
ATOM 539  O O   . SER A 1 74  ? 119.751 115.279 107.631 1.00 101.41 ? 74  SER L O   1 
ATOM 540  C CB  . SER A 1 74  ? 117.425 117.541 107.719 1.00 101.41 ? 74  SER L CB  1 
ATOM 541  O OG  . SER A 1 74  ? 117.190 116.547 106.738 1.00 101.41 ? 74  SER L OG  1 
ATOM 542  N N   . GLY A 1 75  ? 118.658 115.273 109.597 1.00 101.71 ? 75  GLY L N   1 
ATOM 543  C CA  . GLY A 1 75  ? 119.036 113.906 109.909 1.00 101.71 ? 75  GLY L CA  1 
ATOM 544  C C   . GLY A 1 75  ? 117.844 113.043 110.243 1.00 101.71 ? 75  GLY L C   1 
ATOM 545  O O   . GLY A 1 75  ? 116.945 113.446 110.988 1.00 101.71 ? 75  GLY L O   1 
ATOM 546  N N   . SER A 1 76  ? 117.845 111.834 109.685 1.00 104.25 ? 76  SER L N   1 
ATOM 547  C CA  . SER A 1 76  ? 116.870 110.803 110.014 1.00 104.25 ? 76  SER L CA  1 
ATOM 548  C C   . SER A 1 76  ? 117.605 109.601 110.589 1.00 104.25 ? 76  SER L C   1 
ATOM 549  O O   . SER A 1 76  ? 118.787 109.703 110.930 1.00 104.25 ? 76  SER L O   1 
ATOM 550  C CB  . SER A 1 76  ? 116.044 110.409 108.788 1.00 104.25 ? 76  SER L CB  1 
ATOM 551  O OG  . SER A 1 76  ? 116.867 110.213 107.654 1.00 104.25 ? 76  SER L OG  1 
ATOM 552  N N   . GLY A 1 77  ? 116.914 108.470 110.734 1.00 105.57 ? 77  GLY L N   1 
ATOM 553  C CA  . GLY A 1 77  ? 117.562 107.292 111.291 1.00 105.57 ? 77  GLY L CA  1 
ATOM 554  C C   . GLY A 1 77  ? 118.758 106.834 110.476 1.00 105.57 ? 77  GLY L C   1 
ATOM 555  O O   . GLY A 1 77  ? 119.836 106.587 111.022 1.00 105.57 ? 77  GLY L O   1 
ATOM 556  N N   . THR A 1 78  ? 118.586 106.714 109.156 1.00 107.56 ? 78  THR L N   1 
ATOM 557  C CA  . THR A 1 78  ? 119.705 106.295 108.319 1.00 107.56 ? 78  THR L CA  1 
ATOM 558  C C   . THR A 1 78  ? 119.767 107.000 106.967 1.00 107.56 ? 78  THR L C   1 
ATOM 559  O O   . THR A 1 78  ? 120.647 106.663 106.165 1.00 107.56 ? 78  THR L O   1 
ATOM 560  C CB  . THR A 1 78  ? 119.661 104.778 108.091 1.00 107.56 ? 78  THR L CB  1 
ATOM 561  O OG1 . THR A 1 78  ? 120.853 104.362 107.414 1.00 107.56 ? 78  THR L OG1 1 
ATOM 562  C CG2 . THR A 1 78  ? 118.449 104.401 107.255 1.00 107.56 ? 78  THR L CG2 1 
ATOM 563  N N   . ASP A 1 79  ? 118.886 107.961 106.679 1.00 107.34 ? 79  ASP L N   1 
ATOM 564  C CA  . ASP A 1 79  ? 118.838 108.629 105.378 1.00 107.34 ? 79  ASP L CA  1 
ATOM 565  C C   . ASP A 1 79  ? 119.033 110.132 105.592 1.00 107.34 ? 79  ASP L C   1 
ATOM 566  O O   . ASP A 1 79  ? 118.079 110.879 105.811 1.00 107.34 ? 79  ASP L O   1 
ATOM 567  C CB  . ASP A 1 79  ? 117.528 108.327 104.653 1.00 107.34 ? 79  ASP L CB  1 
ATOM 568  C CG  . ASP A 1 79  ? 117.429 106.881 104.210 1.00 107.34 ? 79  ASP L CG  1 
ATOM 569  O OD1 . ASP A 1 79  ? 118.483 106.266 103.946 1.00 107.34 ? 79  ASP L OD1 1 
ATOM 570  O OD2 . ASP A 1 79  ? 116.299 106.359 104.127 1.00 107.34 ? 79  ASP L OD2 1 
ATOM 571  N N   . PHE A 1 80  ? 120.285 110.569 105.517 1.00 101.77 ? 80  PHE L N   1 
ATOM 572  C CA  . PHE A 1 80  ? 120.637 111.946 105.814 1.00 101.77 ? 80  PHE L CA  1 
ATOM 573  C C   . PHE A 1 80  ? 120.864 112.735 104.530 1.00 101.77 ? 80  PHE L C   1 
ATOM 574  O O   . PHE A 1 80  ? 121.043 112.175 103.446 1.00 101.77 ? 80  PHE L O   1 
ATOM 575  C CB  . PHE A 1 80  ? 121.888 112.004 106.688 1.00 101.77 ? 80  PHE L CB  1 
ATOM 576  C CG  . PHE A 1 80  ? 121.825 111.126 107.907 1.00 101.77 ? 80  PHE L CG  1 
ATOM 577  C CD1 . PHE A 1 80  ? 122.019 109.757 107.811 1.00 101.77 ? 80  PHE L CD1 1 
ATOM 578  C CD2 . PHE A 1 80  ? 121.603 111.676 109.155 1.00 101.77 ? 80  PHE L CD2 1 
ATOM 579  C CE1 . PHE A 1 80  ? 121.973 108.959 108.933 1.00 101.77 ? 80  PHE L CE1 1 
ATOM 580  C CE2 . PHE A 1 80  ? 121.558 110.882 110.279 1.00 101.77 ? 80  PHE L CE2 1 
ATOM 581  C CZ  . PHE A 1 80  ? 121.743 109.522 110.168 1.00 101.77 ? 80  PHE L CZ  1 
ATOM 582  N N   . THR A 1 81  ? 120.858 114.059 104.665 1.00 103.65 ? 81  THR L N   1 
ATOM 583  C CA  . THR A 1 81  ? 121.041 114.937 103.521 1.00 103.65 ? 81  THR L CA  1 
ATOM 584  C C   . THR A 1 81  ? 121.768 116.198 103.960 1.00 103.65 ? 81  THR L C   1 
ATOM 585  O O   . THR A 1 81  ? 121.728 116.582 105.132 1.00 103.65 ? 81  THR L O   1 
ATOM 586  C CB  . THR A 1 81  ? 119.704 115.308 102.872 1.00 103.65 ? 81  THR L CB  1 
ATOM 587  O OG1 . THR A 1 81  ? 119.935 116.202 101.778 1.00 103.65 ? 81  THR L OG1 1 
ATOM 588  C CG2 . THR A 1 81  ? 118.794 115.984 103.881 1.00 103.65 ? 81  THR L CG2 1 
ATOM 589  N N   . LEU A 1 82  ? 122.438 116.836 103.003 1.00 100.99 ? 82  LEU L N   1 
ATOM 590  C CA  . LEU A 1 82  ? 123.111 118.111 103.212 1.00 100.99 ? 82  LEU L CA  1 
ATOM 591  C C   . LEU A 1 82  ? 122.588 119.090 102.174 1.00 100.99 ? 82  LEU L C   1 
ATOM 592  O O   . LEU A 1 82  ? 122.762 118.873 100.970 1.00 100.99 ? 82  LEU L O   1 
ATOM 593  C CB  . LEU A 1 82  ? 124.629 117.960 103.098 1.00 100.99 ? 82  LEU L CB  1 
ATOM 594  C CG  . LEU A 1 82  ? 125.467 119.236 102.982 1.00 100.99 ? 82  LEU L CG  1 
ATOM 595  C CD1 . LEU A 1 82  ? 125.121 120.218 104.088 1.00 100.99 ? 82  LEU L CD1 1 
ATOM 596  C CD2 . LEU A 1 82  ? 126.953 118.911 103.002 1.00 100.99 ? 82  LEU L CD2 1 
ATOM 597  N N   . THR A 1 83  ? 121.950 120.159 102.635 1.00 105.64 ? 83  THR L N   1 
ATOM 598  C CA  . THR A 1 83  ? 121.306 121.135 101.758 1.00 105.64 ? 83  THR L CA  1 
ATOM 599  C C   . THR A 1 83  ? 122.062 122.465 101.827 1.00 105.64 ? 83  THR L C   1 
ATOM 600  O O   . THR A 1 83  ? 121.772 123.338 102.647 1.00 105.64 ? 83  THR L O   1 
ATOM 601  C CB  . THR A 1 83  ? 119.797 121.262 102.103 1.00 105.64 ? 83  THR L CB  1 
ATOM 602  O OG1 . THR A 1 83  ? 119.138 122.102 101.146 1.00 105.64 ? 83  THR L OG1 1 
ATOM 603  C CG2 . THR A 1 83  ? 119.534 121.726 103.539 1.00 105.64 ? 83  THR L CG2 1 
ATOM 604  N N   . ILE A 1 84  ? 123.055 122.607 100.950 1.00 110.63 ? 84  ILE L N   1 
ATOM 605  C CA  . ILE A 1 84  ? 123.752 123.880 100.815 1.00 110.63 ? 84  ILE L CA  1 
ATOM 606  C C   . ILE A 1 84  ? 122.785 124.909 100.246 1.00 110.63 ? 84  ILE L C   1 
ATOM 607  O O   . ILE A 1 84  ? 122.086 124.653 99.258  1.00 110.63 ? 84  ILE L O   1 
ATOM 608  C CB  . ILE A 1 84  ? 125.012 123.721 99.953  1.00 110.63 ? 84  ILE L CB  1 
ATOM 609  C CG1 . ILE A 1 84  ? 125.852 124.999 99.973  1.00 110.63 ? 84  ILE L CG1 1 
ATOM 610  C CG2 . ILE A 1 84  ? 124.678 123.299 98.541  1.00 110.63 ? 84  ILE L CG2 1 
ATOM 611  C CD1 . ILE A 1 84  ? 127.234 124.818 99.392  1.00 110.63 ? 84  ILE L CD1 1 
ATOM 612  N N   . SER A 1 85  ? 122.709 126.070 100.895 1.00 113.53 ? 85  SER L N   1 
ATOM 613  C CA  . SER A 1 85  ? 121.798 127.131 100.466 1.00 113.53 ? 85  SER L CA  1 
ATOM 614  C C   . SER A 1 85  ? 122.490 127.992 99.409  1.00 113.53 ? 85  SER L C   1 
ATOM 615  O O   . SER A 1 85  ? 123.090 129.030 99.694  1.00 113.53 ? 85  SER L O   1 
ATOM 616  C CB  . SER A 1 85  ? 121.339 127.957 101.659 1.00 113.53 ? 85  SER L CB  1 
ATOM 617  O OG  . SER A 1 85  ? 120.515 129.030 101.241 1.00 113.53 ? 85  SER L OG  1 
ATOM 618  N N   . SER A 1 86  ? 122.417 127.502 98.168  1.00 118.06 ? 86  SER L N   1 
ATOM 619  C CA  . SER A 1 86  ? 123.012 128.129 96.991  1.00 118.06 ? 86  SER L CA  1 
ATOM 620  C C   . SER A 1 86  ? 124.528 127.977 97.018  1.00 118.06 ? 86  SER L C   1 
ATOM 621  O O   . SER A 1 86  ? 125.128 127.841 98.088  1.00 118.06 ? 86  SER L O   1 
ATOM 622  C CB  . SER A 1 86  ? 122.611 129.603 96.873  1.00 118.06 ? 86  SER L CB  1 
ATOM 623  O OG  . SER A 1 86  ? 121.272 129.728 96.428  1.00 118.06 ? 86  SER L OG  1 
ATOM 624  N N   . VAL A 1 87  ? 125.155 127.998 95.847  1.00 115.57 ? 87  VAL L N   1 
ATOM 625  C CA  . VAL A 1 87  ? 126.589 127.782 95.720  1.00 115.57 ? 87  VAL L CA  1 
ATOM 626  C C   . VAL A 1 87  ? 127.227 129.037 95.145  1.00 115.57 ? 87  VAL L C   1 
ATOM 627  O O   . VAL A 1 87  ? 126.701 129.643 94.205  1.00 115.57 ? 87  VAL L O   1 
ATOM 628  C CB  . VAL A 1 87  ? 126.902 126.543 94.853  1.00 115.57 ? 87  VAL L CB  1 
ATOM 629  C CG1 . VAL A 1 87  ? 126.342 126.703 93.449  1.00 115.57 ? 87  VAL L CG1 1 
ATOM 630  C CG2 . VAL A 1 87  ? 128.399 126.292 94.808  1.00 115.57 ? 87  VAL L CG2 1 
ATOM 631  N N   . LYS A 1 88  ? 128.336 129.454 95.749  1.00 112.93 ? 88  LYS L N   1 
ATOM 632  C CA  . LYS A 1 88  ? 129.110 130.587 95.273  1.00 112.93 ? 88  LYS L CA  1 
ATOM 633  C C   . LYS A 1 88  ? 130.296 130.108 94.439  1.00 112.93 ? 88  LYS L C   1 
ATOM 634  O O   . LYS A 1 88  ? 130.394 128.939 94.061  1.00 112.93 ? 88  LYS L O   1 
ATOM 635  C CB  . LYS A 1 88  ? 129.552 131.463 96.444  1.00 112.93 ? 88  LYS L CB  1 
ATOM 636  C CG  . LYS A 1 88  ? 128.468 132.411 96.948  1.00 112.93 ? 88  LYS L CG  1 
ATOM 637  C CD  . LYS A 1 88  ? 127.374 131.694 97.714  1.00 112.93 ? 88  LYS L CD  1 
ATOM 638  C CE  . LYS A 1 88  ? 126.364 132.676 98.283  1.00 112.93 ? 88  LYS L CE  1 
ATOM 639  N NZ  . LYS A 1 88  ? 125.219 131.984 98.939  1.00 112.93 ? 88  LYS L NZ  1 
ATOM 640  N N   . ALA A 1 89  ? 131.205 131.038 94.137  1.00 114.33 ? 89  ALA L N   1 
ATOM 641  C CA  . ALA A 1 89  ? 132.311 130.734 93.236  1.00 114.33 ? 89  ALA L CA  1 
ATOM 642  C C   . ALA A 1 89  ? 133.188 129.615 93.781  1.00 114.33 ? 89  ALA L C   1 
ATOM 643  O O   . ALA A 1 89  ? 133.619 128.735 93.028  1.00 114.33 ? 89  ALA L O   1 
ATOM 644  C CB  . ALA A 1 89  ? 133.143 131.991 92.984  1.00 114.33 ? 89  ALA L CB  1 
ATOM 645  N N   . GLU A 1 90  ? 133.465 129.626 95.080  1.00 112.44 ? 90  GLU L N   1 
ATOM 646  C CA  . GLU A 1 90  ? 134.302 128.605 95.703  1.00 112.44 ? 90  GLU L CA  1 
ATOM 647  C C   . GLU A 1 90  ? 133.523 127.955 96.844  1.00 112.44 ? 90  GLU L C   1 
ATOM 648  O O   . GLU A 1 90  ? 133.658 128.334 98.011  1.00 112.44 ? 90  GLU L O   1 
ATOM 649  C CB  . GLU A 1 90  ? 135.625 129.204 96.188  1.00 112.44 ? 90  GLU L CB  1 
ATOM 650  C CG  . GLU A 1 90  ? 136.571 128.193 96.819  1.00 112.44 ? 90  GLU L CG  1 
ATOM 651  C CD  . GLU A 1 90  ? 136.505 126.835 96.146  1.00 112.44 ? 90  GLU L CD  1 
ATOM 652  O OE1 . GLU A 1 90  ? 137.121 126.671 95.072  1.00 112.44 ? 90  GLU L OE1 1 
ATOM 653  O OE2 . GLU A 1 90  ? 135.842 125.929 96.693  1.00 112.44 ? 90  GLU L OE2 1 
ATOM 654  N N   . ASP A 1 91  ? 132.707 126.966 96.490  1.00 110.31 ? 91  ASP L N   1 
ATOM 655  C CA  . ASP A 1 91  ? 132.069 126.036 97.414  1.00 110.31 ? 91  ASP L CA  1 
ATOM 656  C C   . ASP A 1 91  ? 132.051 124.650 96.791  1.00 110.31 ? 91  ASP L C   1 
ATOM 657  O O   . ASP A 1 91  ? 131.232 123.794 97.142  1.00 110.31 ? 91  ASP L O   1 
ATOM 658  C CB  . ASP A 1 91  ? 130.657 126.488 97.786  1.00 110.31 ? 91  ASP L CB  1 
ATOM 659  C CG  . ASP A 1 91  ? 130.653 127.638 98.775  1.00 110.31 ? 91  ASP L CG  1 
ATOM 660  O OD1 . ASP A 1 91  ? 131.574 127.711 99.612  1.00 110.31 ? 91  ASP L OD1 1 
ATOM 661  O OD2 . ASP A 1 91  ? 129.726 128.473 98.716  1.00 110.31 ? 91  ASP L OD2 1 
ATOM 662  N N   . LEU A 1 92  ? 132.964 124.425 95.849  1.00 106.43 ? 92  LEU L N   1 
ATOM 663  C CA  . LEU A 1 92  ? 133.043 123.196 95.071  1.00 106.43 ? 92  LEU L CA  1 
ATOM 664  C C   . LEU A 1 92  ? 133.946 122.177 95.751  1.00 106.43 ? 92  LEU L C   1 
ATOM 665  O O   . LEU A 1 92  ? 134.216 122.284 96.952  1.00 106.43 ? 92  LEU L O   1 
ATOM 666  C CB  . LEU A 1 92  ? 133.545 123.485 93.653  1.00 106.43 ? 92  LEU L CB  1 
ATOM 667  C CG  . LEU A 1 92  ? 132.547 123.965 92.593  1.00 106.43 ? 92  LEU L CG  1 
ATOM 668  C CD1 . LEU A 1 92  ? 131.507 122.890 92.320  1.00 106.43 ? 92  LEU L CD1 1 
ATOM 669  C CD2 . LEU A 1 92  ? 131.882 125.281 92.970  1.00 106.43 ? 92  LEU L CD2 1 
ATOM 670  N N   . ALA A 1 93  ? 134.360 121.161 94.989  1.00 101.29 ? 93  ALA L N   1 
ATOM 671  C CA  . ALA A 1 93  ? 135.279 120.109 95.414  1.00 101.29 ? 93  ALA L CA  1 
ATOM 672  C C   . ALA A 1 93  ? 134.574 119.089 96.297  1.00 101.29 ? 93  ALA L C   1 
ATOM 673  O O   . ALA A 1 93  ? 133.379 119.219 96.577  1.00 101.29 ? 93  ALA L O   1 
ATOM 674  C CB  . ALA A 1 93  ? 136.504 120.687 96.128  1.00 101.29 ? 93  ALA L CB  1 
ATOM 675  N N   . ILE A 1 94  ? 135.313 118.067 96.730  1.00 98.45  ? 94  ILE L N   1 
ATOM 676  C CA  . ILE A 1 94  ? 134.708 116.890 97.339  1.00 98.45  ? 94  ILE L CA  1 
ATOM 677  C C   . ILE A 1 94  ? 134.053 117.248 98.669  1.00 98.45  ? 94  ILE L C   1 
ATOM 678  O O   . ILE A 1 94  ? 134.586 118.032 99.464  1.00 98.45  ? 94  ILE L O   1 
ATOM 679  C CB  . ILE A 1 94  ? 135.771 115.792 97.518  1.00 98.45  ? 94  ILE L CB  1 
ATOM 680  C CG1 . ILE A 1 94  ? 136.340 115.384 96.160  1.00 98.45  ? 94  ILE L CG1 1 
ATOM 681  C CG2 . ILE A 1 94  ? 135.177 114.584 98.205  1.00 98.45  ? 94  ILE L CG2 1 
ATOM 682  C CD1 . ILE A 1 94  ? 137.564 114.507 96.254  1.00 98.45  ? 94  ILE L CD1 1 
ATOM 683  N N   . TYR A 1 95  ? 132.878 116.667 98.912  1.00 95.76  ? 95  TYR L N   1 
ATOM 684  C CA  . TYR A 1 95  ? 132.140 116.821 100.165 1.00 95.76  ? 95  TYR L CA  1 
ATOM 685  C C   . TYR A 1 95  ? 132.021 115.444 100.809 1.00 95.76  ? 95  TYR L C   1 
ATOM 686  O O   . TYR A 1 95  ? 131.067 114.705 100.553 1.00 95.76  ? 95  TYR L O   1 
ATOM 687  C CB  . TYR A 1 95  ? 130.774 117.442 99.926  1.00 95.76  ? 95  TYR L CB  1 
ATOM 688  C CG  . TYR A 1 95  ? 130.794 118.946 99.912  1.00 95.76  ? 95  TYR L CG  1 
ATOM 689  C CD1 . TYR A 1 95  ? 131.560 119.636 98.988  1.00 95.76  ? 95  TYR L CD1 1 
ATOM 690  C CD2 . TYR A 1 95  ? 130.051 119.678 100.824 1.00 95.76  ? 95  TYR L CD2 1 
ATOM 691  C CE1 . TYR A 1 95  ? 131.586 121.011 98.969  1.00 95.76  ? 95  TYR L CE1 1 
ATOM 692  C CE2 . TYR A 1 95  ? 130.071 121.055 100.814 1.00 95.76  ? 95  TYR L CE2 1 
ATOM 693  C CZ  . TYR A 1 95  ? 130.840 121.717 99.884  1.00 95.76  ? 95  TYR L CZ  1 
ATOM 694  O OH  . TYR A 1 95  ? 130.866 123.091 99.867  1.00 95.76  ? 95  TYR L OH  1 
ATOM 695  N N   . TYR A 1 96  ? 132.991 115.103 101.649 1.00 94.48  ? 96  TYR L N   1 
ATOM 696  C CA  . TYR A 1 96  ? 133.015 113.809 102.308 1.00 94.48  ? 96  TYR L CA  1 
ATOM 697  C C   . TYR A 1 96  ? 131.999 113.752 103.443 1.00 94.48  ? 96  TYR L C   1 
ATOM 698  O O   . TYR A 1 96  ? 131.635 114.766 104.042 1.00 94.48  ? 96  TYR L O   1 
ATOM 699  C CB  . TYR A 1 96  ? 134.412 113.516 102.848 1.00 94.48  ? 96  TYR L CB  1 
ATOM 700  C CG  . TYR A 1 96  ? 135.391 113.098 101.782 1.00 94.48  ? 96  TYR L CG  1 
ATOM 701  C CD1 . TYR A 1 96  ? 135.099 112.054 100.920 1.00 94.48  ? 96  TYR L CD1 1 
ATOM 702  C CD2 . TYR A 1 96  ? 136.598 113.759 101.624 1.00 94.48  ? 96  TYR L CD2 1 
ATOM 703  C CE1 . TYR A 1 96  ? 135.986 111.668 99.943  1.00 94.48  ? 96  TYR L CE1 1 
ATOM 704  C CE2 . TYR A 1 96  ? 137.490 113.385 100.645 1.00 94.48  ? 96  TYR L CE2 1 
ATOM 705  C CZ  . TYR A 1 96  ? 137.181 112.337 99.809  1.00 94.48  ? 96  TYR L CZ  1 
ATOM 706  O OH  . TYR A 1 96  ? 138.069 111.957 98.830  1.00 94.48  ? 96  TYR L OH  1 
ATOM 707  N N   . CYS A 1 97  ? 131.544 112.536 103.736 1.00 88.89  ? 97  CYS L N   1 
ATOM 708  C CA  . CYS A 1 97  ? 130.672 112.275 104.870 1.00 88.89  ? 97  CYS L CA  1 
ATOM 709  C C   . CYS A 1 97  ? 131.289 111.164 105.701 1.00 88.89  ? 97  CYS L C   1 
ATOM 710  O O   . CYS A 1 97  ? 132.006 110.308 105.179 1.00 88.89  ? 97  CYS L O   1 
ATOM 711  C CB  . CYS A 1 97  ? 129.259 111.881 104.431 1.00 88.89  ? 97  CYS L CB  1 
ATOM 712  S SG  . CYS A 1 97  ? 129.157 110.270 103.632 1.00 88.89  ? 97  CYS L SG  1 
ATOM 713  N N   . GLN A 1 98  ? 131.012 111.182 107.001 1.00 81.83  ? 98  GLN L N   1 
ATOM 714  C CA  . GLN A 1 98  ? 131.684 110.268 107.909 1.00 81.83  ? 98  GLN L CA  1 
ATOM 715  C C   . GLN A 1 98  ? 130.827 110.015 109.137 1.00 81.83  ? 98  GLN L C   1 
ATOM 716  O O   . GLN A 1 98  ? 130.267 110.951 109.712 1.00 81.83  ? 98  GLN L O   1 
ATOM 717  C CB  . GLN A 1 98  ? 133.040 110.833 108.340 1.00 81.83  ? 98  GLN L CB  1 
ATOM 718  C CG  . GLN A 1 98  ? 133.572 110.249 109.633 1.00 81.83  ? 98  GLN L CG  1 
ATOM 719  C CD  . GLN A 1 98  ? 134.712 111.060 110.201 1.00 81.83  ? 98  GLN L CD  1 
ATOM 720  O OE1 . GLN A 1 98  ? 135.341 111.839 109.494 1.00 81.83  ? 98  GLN L OE1 1 
ATOM 721  N NE2 . GLN A 1 98  ? 134.992 110.873 111.481 1.00 81.83  ? 98  GLN L NE2 1 
ATOM 722  N N   . GLN A 1 99  ? 130.737 108.750 109.538 1.00 83.14  ? 99  GLN L N   1 
ATOM 723  C CA  . GLN A 1 99  ? 130.247 108.404 110.863 1.00 83.14  ? 99  GLN L CA  1 
ATOM 724  C C   . GLN A 1 99  ? 131.455 108.175 111.757 1.00 83.14  ? 99  GLN L C   1 
ATOM 725  O O   . GLN A 1 99  ? 132.467 107.622 111.322 1.00 83.14  ? 99  GLN L O   1 
ATOM 726  C CB  . GLN A 1 99  ? 129.337 107.171 110.820 1.00 83.14  ? 99  GLN L CB  1 
ATOM 727  C CG  . GLN A 1 99  ? 130.015 105.827 110.594 1.00 83.14  ? 99  GLN L CG  1 
ATOM 728  C CD  . GLN A 1 99  ? 130.551 105.204 111.871 1.00 83.14  ? 99  GLN L CD  1 
ATOM 729  O OE1 . GLN A 1 99  ? 130.427 105.773 112.954 1.00 83.14  ? 99  GLN L OE1 1 
ATOM 730  N NE2 . GLN A 1 99  ? 131.143 104.024 111.747 1.00 83.14  ? 99  GLN L NE2 1 
ATOM 731  N N   . TYR A 1 100 ? 131.354 108.622 113.008 1.00 79.21  ? 100 TYR L N   1 
ATOM 732  C CA  . TYR A 1 100 ? 132.509 108.728 113.887 1.00 79.21  ? 100 TYR L CA  1 
ATOM 733  C C   . TYR A 1 100 ? 132.209 108.194 115.292 1.00 79.21  ? 100 TYR L C   1 
ATOM 734  O O   . TYR A 1 100 ? 132.548 108.780 116.314 1.00 79.21  ? 100 TYR L O   1 
ATOM 735  C CB  . TYR A 1 100 ? 133.023 110.169 113.896 1.00 79.21  ? 100 TYR L CB  1 
ATOM 736  C CG  . TYR A 1 100 ? 132.057 111.200 114.428 1.00 79.21  ? 100 TYR L CG  1 
ATOM 737  C CD1 . TYR A 1 100 ? 131.171 111.831 113.572 1.00 79.21  ? 100 TYR L CD1 1 
ATOM 738  C CD2 . TYR A 1 100 ? 132.059 111.580 115.758 1.00 79.21  ? 100 TYR L CD2 1 
ATOM 739  C CE1 . TYR A 1 100 ? 130.296 112.779 114.026 1.00 79.21  ? 100 TYR L CE1 1 
ATOM 740  C CE2 . TYR A 1 100 ? 131.182 112.530 116.223 1.00 79.21  ? 100 TYR L CE2 1 
ATOM 741  C CZ  . TYR A 1 100 ? 130.306 113.127 115.350 1.00 79.21  ? 100 TYR L CZ  1 
ATOM 742  O OH  . TYR A 1 100 ? 129.430 114.080 115.799 1.00 79.21  ? 100 TYR L OH  1 
ATOM 743  N N   . PHE A 1 101 ? 131.596 107.017 115.347 1.00 86.41  ? 101 PHE L N   1 
ATOM 744  C CA  . PHE A 1 101 ? 131.480 106.272 116.590 1.00 86.41  ? 101 PHE L CA  1 
ATOM 745  C C   . PHE A 1 101 ? 132.153 104.923 116.406 1.00 86.41  ? 101 PHE L C   1 
ATOM 746  O O   . PHE A 1 101 ? 131.975 104.274 115.371 1.00 86.41  ? 101 PHE L O   1 
ATOM 747  C CB  . PHE A 1 101 ? 130.024 106.070 117.005 1.00 86.41  ? 101 PHE L CB  1 
ATOM 748  C CG  . PHE A 1 101 ? 129.864 105.356 118.313 1.00 86.41  ? 101 PHE L CG  1 
ATOM 749  C CD1 . PHE A 1 101 ? 130.368 105.904 119.479 1.00 86.41  ? 101 PHE L CD1 1 
ATOM 750  C CD2 . PHE A 1 101 ? 129.216 104.137 118.379 1.00 86.41  ? 101 PHE L CD2 1 
ATOM 751  C CE1 . PHE A 1 101 ? 130.224 105.252 120.686 1.00 86.41  ? 101 PHE L CE1 1 
ATOM 752  C CE2 . PHE A 1 101 ? 129.069 103.480 119.583 1.00 86.41  ? 101 PHE L CE2 1 
ATOM 753  C CZ  . PHE A 1 101 ? 129.574 104.038 120.738 1.00 86.41  ? 101 PHE L CZ  1 
ATOM 754  N N   . ARG A 1 102 ? 132.922 104.507 117.412 1.00 93.63  ? 102 ARG L N   1 
ATOM 755  C CA  . ARG A 1 102 ? 133.705 103.269 117.364 1.00 93.63  ? 102 ARG L CA  1 
ATOM 756  C C   . ARG A 1 102 ? 134.652 103.374 116.174 1.00 93.63  ? 102 ARG L C   1 
ATOM 757  O O   . ARG A 1 102 ? 135.578 104.201 116.222 1.00 93.63  ? 102 ARG L O   1 
ATOM 758  C CB  . ARG A 1 102 ? 132.760 102.066 117.364 1.00 93.63  ? 102 ARG L CB  1 
ATOM 759  C CG  . ARG A 1 102 ? 132.540 101.447 118.736 1.00 93.63  ? 102 ARG L CG  1 
ATOM 760  C CD  . ARG A 1 102 ? 131.825 100.103 118.650 1.00 93.63  ? 102 ARG L CD  1 
ATOM 761  N NE  . ARG A 1 102 ? 130.616 100.159 117.836 1.00 93.63  ? 102 ARG L NE  1 
ATOM 762  C CZ  . ARG A 1 102 ? 130.519 99.695  116.597 1.00 93.63  ? 102 ARG L CZ  1 
ATOM 763  N NH1 . ARG A 1 102 ? 131.548 99.129  115.989 1.00 93.63  ? 102 ARG L NH1 1 
ATOM 764  N NH2 . ARG A 1 102 ? 129.361 99.803  115.952 1.00 93.63  ? 102 ARG L NH2 1 
ATOM 765  N N   . TYR A 1 103 ? 134.479 102.588 115.113 1.00 92.62  ? 103 TYR L N   1 
ATOM 766  C CA  . TYR A 1 103 ? 135.391 102.627 113.977 1.00 92.62  ? 103 TYR L CA  1 
ATOM 767  C C   . TYR A 1 103 ? 134.863 103.608 112.940 1.00 92.62  ? 103 TYR L C   1 
ATOM 768  O O   . TYR A 1 103 ? 133.799 103.359 112.354 1.00 92.62  ? 103 TYR L O   1 
ATOM 769  C CB  . TYR A 1 103 ? 135.549 101.241 113.363 1.00 92.62  ? 103 TYR L CB  1 
ATOM 770  C CG  . TYR A 1 103 ? 136.244 100.219 114.244 1.00 92.62  ? 103 TYR L CG  1 
ATOM 771  C CD1 . TYR A 1 103 ? 136.523 100.485 115.578 1.00 92.62  ? 103 TYR L CD1 1 
ATOM 772  C CD2 . TYR A 1 103 ? 136.636 98.992  113.729 1.00 92.62  ? 103 TYR L CD2 1 
ATOM 773  C CE1 . TYR A 1 103 ? 137.158 99.556  116.376 1.00 92.62  ? 103 TYR L CE1 1 
ATOM 774  C CE2 . TYR A 1 103 ? 137.273 98.056  114.520 1.00 92.62  ? 103 TYR L CE2 1 
ATOM 775  C CZ  . TYR A 1 103 ? 137.532 98.344  115.842 1.00 92.62  ? 103 TYR L CZ  1 
ATOM 776  O OH  . TYR A 1 103 ? 138.167 97.417  116.635 1.00 92.62  ? 103 TYR L OH  1 
ATOM 777  N N   . PRO A 1 104 ? 135.551 104.716 112.678 1.00 84.06  ? 104 PRO L N   1 
ATOM 778  C CA  . PRO A 1 104 ? 135.076 105.659 111.663 1.00 84.06  ? 104 PRO L CA  1 
ATOM 779  C C   . PRO A 1 104 ? 135.249 105.106 110.257 1.00 84.06  ? 104 PRO L C   1 
ATOM 780  O O   . PRO A 1 104 ? 136.034 104.190 110.008 1.00 84.06  ? 104 PRO L O   1 
ATOM 781  C CB  . PRO A 1 104 ? 135.960 106.892 111.884 1.00 84.06  ? 104 PRO L CB  1 
ATOM 782  C CG  . PRO A 1 104 ? 136.525 106.718 113.263 1.00 84.06  ? 104 PRO L CG  1 
ATOM 783  C CD  . PRO A 1 104 ? 136.709 105.247 113.410 1.00 84.06  ? 104 PRO L CD  1 
ATOM 784  N N   . ALA A 1 105 ? 134.493 105.685 109.326 1.00 83.14  ? 105 ALA L N   1 
ATOM 785  C CA  . ALA A 1 105 ? 134.547 105.256 107.931 1.00 83.14  ? 105 ALA L CA  1 
ATOM 786  C C   . ALA A 1 105 ? 133.988 106.360 107.051 1.00 83.14  ? 105 ALA L C   1 
ATOM 787  O O   . ALA A 1 105 ? 132.822 106.735 107.198 1.00 83.14  ? 105 ALA L O   1 
ATOM 788  C CB  . ALA A 1 105 ? 133.764 103.961 107.731 1.00 83.14  ? 105 ALA L CB  1 
ATOM 789  N N   . PHE A 1 106 ? 134.809 106.869 106.138 1.00 87.49  ? 106 PHE L N   1 
ATOM 790  C CA  . PHE A 1 106 ? 134.395 107.895 105.194 1.00 87.49  ? 106 PHE L CA  1 
ATOM 791  C C   . PHE A 1 106 ? 133.688 107.270 103.994 1.00 87.49  ? 106 PHE L C   1 
ATOM 792  O O   . PHE A 1 106 ? 133.355 106.085 103.978 1.00 87.49  ? 106 PHE L O   1 
ATOM 793  C CB  . PHE A 1 106 ? 135.595 108.709 104.712 1.00 87.49  ? 106 PHE L CB  1 
ATOM 794  C CG  . PHE A 1 106 ? 136.319 109.445 105.800 1.00 87.49  ? 106 PHE L CG  1 
ATOM 795  C CD1 . PHE A 1 106 ? 137.158 108.778 106.671 1.00 87.49  ? 106 PHE L CD1 1 
ATOM 796  C CD2 . PHE A 1 106 ? 136.184 110.813 105.930 1.00 87.49  ? 106 PHE L CD2 1 
ATOM 797  C CE1 . PHE A 1 106 ? 137.828 109.457 107.662 1.00 87.49  ? 106 PHE L CE1 1 
ATOM 798  C CE2 . PHE A 1 106 ? 136.857 111.496 106.915 1.00 87.49  ? 106 PHE L CE2 1 
ATOM 799  C CZ  . PHE A 1 106 ? 137.679 110.817 107.783 1.00 87.49  ? 106 PHE L CZ  1 
ATOM 800  N N   . GLY A 1 107 ? 133.457 108.097 102.978 1.00 94.68  ? 107 GLY L N   1 
ATOM 801  C CA  . GLY A 1 107 ? 132.927 107.619 101.716 1.00 94.68  ? 107 GLY L CA  1 
ATOM 802  C C   . GLY A 1 107 ? 132.159 108.674 100.950 1.00 94.68  ? 107 GLY L C   1 
ATOM 803  O O   . GLY A 1 107 ? 131.381 109.429 101.539 1.00 94.68  ? 107 GLY L O   1 
ATOM 804  N N   . GLY A 1 108 ? 132.362 108.740 99.644  1.00 101.12 ? 108 GLY L N   1 
ATOM 805  C CA  . GLY A 1 108 ? 131.608 109.646 98.805  1.00 101.12 ? 108 GLY L CA  1 
ATOM 806  C C   . GLY A 1 108 ? 132.532 110.506 97.968  1.00 101.12 ? 108 GLY L C   1 
ATOM 807  O O   . GLY A 1 108 ? 133.749 110.351 97.994  1.00 101.12 ? 108 GLY L O   1 
ATOM 808  N N   . GLY A 1 109 ? 131.919 111.428 97.230  1.00 100.30 ? 109 GLY L N   1 
ATOM 809  C CA  . GLY A 1 109 ? 132.653 112.294 96.328  1.00 100.30 ? 109 GLY L CA  1 
ATOM 810  C C   . GLY A 1 109 ? 132.042 113.671 96.168  1.00 100.30 ? 109 GLY L C   1 
ATOM 811  O O   . GLY A 1 109 ? 131.234 114.099 96.997  1.00 100.30 ? 109 GLY L O   1 
ATOM 812  N N   . THR A 1 110 ? 132.428 114.371 95.103  1.00 102.15 ? 110 THR L N   1 
ATOM 813  C CA  . THR A 1 110 ? 131.971 115.736 94.841  1.00 102.15 ? 110 THR L CA  1 
ATOM 814  C C   . THR A 1 110 ? 130.450 115.834 94.821  1.00 102.15 ? 110 THR L C   1 
ATOM 815  O O   . THR A 1 110 ? 129.871 116.744 95.411  1.00 102.15 ? 110 THR L O   1 
ATOM 816  C CB  . THR A 1 110 ? 132.514 116.265 93.496  1.00 102.15 ? 110 THR L CB  1 
ATOM 817  O OG1 . THR A 1 110 ? 133.944 116.171 93.480  1.00 102.15 ? 110 THR L OG1 1 
ATOM 818  C CG2 . THR A 1 110 ? 132.101 117.713 93.283  1.00 102.15 ? 110 THR L CG2 1 
ATOM 819  N N   . VAL B 2 5   ? 144.456 125.076 118.803 1.00 113.76 ? 5   VAL H N   1 
ATOM 820  C CA  . VAL B 2 5   ? 145.215 123.837 118.691 1.00 113.76 ? 5   VAL H CA  1 
ATOM 821  C C   . VAL B 2 5   ? 145.593 123.583 117.239 1.00 113.76 ? 5   VAL H C   1 
ATOM 822  O O   . VAL B 2 5   ? 144.731 123.530 116.363 1.00 113.76 ? 5   VAL H O   1 
ATOM 823  C CB  . VAL B 2 5   ? 144.428 122.646 119.262 1.00 113.76 ? 5   VAL H CB  1 
ATOM 824  C CG1 . VAL B 2 5   ? 145.029 121.333 118.783 1.00 113.76 ? 5   VAL H CG1 1 
ATOM 825  C CG2 . VAL B 2 5   ? 144.403 122.707 120.781 1.00 113.76 ? 5   VAL H CG2 1 
ATOM 826  N N   . GLN B 2 6   ? 146.890 123.426 116.990 1.00 116.09 ? 6   GLN H N   1 
ATOM 827  C CA  . GLN B 2 6   ? 147.404 123.164 115.656 1.00 116.09 ? 6   GLN H CA  1 
ATOM 828  C C   . GLN B 2 6   ? 148.413 122.027 115.708 1.00 116.09 ? 6   GLN H C   1 
ATOM 829  O O   . GLN B 2 6   ? 149.036 121.773 116.742 1.00 116.09 ? 6   GLN H O   1 
ATOM 830  C CB  . GLN B 2 6   ? 148.026 124.435 115.037 1.00 116.09 ? 6   GLN H CB  1 
ATOM 831  C CG  . GLN B 2 6   ? 149.084 125.155 115.882 1.00 116.09 ? 6   GLN H CG  1 
ATOM 832  C CD  . GLN B 2 6   ? 150.335 124.336 116.130 1.00 116.09 ? 6   GLN H CD  1 
ATOM 833  O OE1 . GLN B 2 6   ? 150.790 124.208 117.266 1.00 116.09 ? 6   GLN H OE1 1 
ATOM 834  N NE2 . GLN B 2 6   ? 150.903 123.785 115.065 1.00 116.09 ? 6   GLN H NE2 1 
ATOM 835  N N   . LEU B 2 7   ? 148.558 121.334 114.583 1.00 113.03 ? 7   LEU H N   1 
ATOM 836  C CA  . LEU B 2 7   ? 149.500 120.231 114.478 1.00 113.03 ? 7   LEU H CA  1 
ATOM 837  C C   . LEU B 2 7   ? 150.039 120.196 113.057 1.00 113.03 ? 7   LEU H C   1 
ATOM 838  O O   . LEU B 2 7   ? 149.307 120.469 112.103 1.00 113.03 ? 7   LEU H O   1 
ATOM 839  C CB  . LEU B 2 7   ? 148.849 118.895 114.857 1.00 113.03 ? 7   LEU H CB  1 
ATOM 840  C CG  . LEU B 2 7   ? 147.896 118.199 113.886 1.00 113.03 ? 7   LEU H CG  1 
ATOM 841  C CD1 . LEU B 2 7   ? 147.614 116.799 114.385 1.00 113.03 ? 7   LEU H CD1 1 
ATOM 842  C CD2 . LEU B 2 7   ? 146.599 118.968 113.709 1.00 113.03 ? 7   LEU H CD2 1 
ATOM 843  N N   . GLN B 2 8   ? 151.320 119.869 112.926 1.00 122.82 ? 8   GLN H N   1 
ATOM 844  C CA  . GLN B 2 8   ? 152.020 120.006 111.656 1.00 122.82 ? 8   GLN H CA  1 
ATOM 845  C C   . GLN B 2 8   ? 153.227 119.075 111.650 1.00 122.82 ? 8   GLN H C   1 
ATOM 846  O O   . GLN B 2 8   ? 153.321 118.149 112.460 1.00 122.82 ? 8   GLN H O   1 
ATOM 847  C CB  . GLN B 2 8   ? 152.379 121.476 111.402 1.00 122.82 ? 8   GLN H CB  1 
ATOM 848  C CG  . GLN B 2 8   ? 153.329 122.116 112.411 1.00 122.82 ? 8   GLN H CG  1 
ATOM 849  C CD  . GLN B 2 8   ? 154.791 121.855 112.128 1.00 122.82 ? 8   GLN H CD  1 
ATOM 850  O OE1 . GLN B 2 8   ? 155.194 121.687 110.977 1.00 122.82 ? 8   GLN H OE1 1 
ATOM 851  N NE2 . GLN B 2 8   ? 155.600 121.844 113.179 1.00 122.82 ? 8   GLN H NE2 1 
ATOM 852  N N   . GLN B 2 9   ? 154.127 119.315 110.687 1.00 126.17 ? 9   GLN H N   1 
ATOM 853  C CA  . GLN B 2 9   ? 155.306 118.511 110.356 1.00 126.17 ? 9   GLN H CA  1 
ATOM 854  C C   . GLN B 2 9   ? 154.929 117.366 109.426 1.00 126.17 ? 9   GLN H C   1 
ATOM 855  O O   . GLN B 2 9   ? 153.832 116.807 109.526 1.00 126.17 ? 9   GLN H O   1 
ATOM 856  C CB  . GLN B 2 9   ? 156.027 117.969 111.596 1.00 126.17 ? 9   GLN H CB  1 
ATOM 857  C CG  . GLN B 2 9   ? 156.804 119.014 112.370 1.00 126.17 ? 9   GLN H CG  1 
ATOM 858  C CD  . GLN B 2 9   ? 158.064 119.451 111.648 1.00 126.17 ? 9   GLN H CD  1 
ATOM 859  O OE1 . GLN B 2 9   ? 158.964 118.649 111.405 1.00 126.17 ? 9   GLN H OE1 1 
ATOM 860  N NE2 . GLN B 2 9   ? 158.131 120.730 111.297 1.00 126.17 ? 9   GLN H NE2 1 
ATOM 861  N N   . SER B 2 10  ? 155.841 117.011 108.522 1.00 127.08 ? 10  SER H N   1 
ATOM 862  C CA  . SER B 2 10  ? 155.557 116.004 107.510 1.00 127.08 ? 10  SER H CA  1 
ATOM 863  C C   . SER B 2 10  ? 156.834 115.446 106.895 1.00 127.08 ? 10  SER H C   1 
ATOM 864  O O   . SER B 2 10  ? 157.521 114.622 107.508 1.00 127.08 ? 10  SER H O   1 
ATOM 865  C CB  . SER B 2 10  ? 154.670 116.598 106.415 1.00 127.08 ? 10  SER H CB  1 
ATOM 866  O OG  . SER B 2 10  ? 155.276 117.743 105.841 1.00 127.08 ? 10  SER H OG  1 
ATOM 867  N N   . GLY B 2 11  ? 157.156 115.892 105.683 1.00 129.94 ? 11  GLY H N   1 
ATOM 868  C CA  . GLY B 2 11  ? 158.319 115.420 104.970 1.00 129.94 ? 11  GLY H CA  1 
ATOM 869  C C   . GLY B 2 11  ? 157.953 114.567 103.772 1.00 129.94 ? 11  GLY H C   1 
ATOM 870  O O   . GLY B 2 11  ? 157.458 113.444 103.907 1.00 129.94 ? 11  GLY H O   1 
ATOM 871  N N   . PRO B 2 12  ? 158.189 115.092 102.568 1.00 130.48 ? 12  PRO H N   1 
ATOM 872  C CA  . PRO B 2 12  ? 157.867 114.327 101.352 1.00 130.48 ? 12  PRO H CA  1 
ATOM 873  C C   . PRO B 2 12  ? 158.766 113.115 101.175 1.00 130.48 ? 12  PRO H C   1 
ATOM 874  O O   . PRO B 2 12  ? 159.686 113.136 100.351 1.00 130.48 ? 12  PRO H O   1 
ATOM 875  C CB  . PRO B 2 12  ? 158.085 115.333 100.214 1.00 130.48 ? 12  PRO H CB  1 
ATOM 876  C CG  . PRO B 2 12  ? 158.308 116.655 100.837 1.00 130.48 ? 12  PRO H CG  1 
ATOM 877  C CD  . PRO B 2 12  ? 158.371 116.531 102.319 1.00 130.48 ? 12  PRO H CD  1 
ATOM 878  N N   . GLU B 2 13  ? 158.511 112.055 101.939 1.00 133.68 ? 13  GLU H N   1 
ATOM 879  C CA  . GLU B 2 13  ? 159.342 110.861 101.859 1.00 133.68 ? 13  GLU H CA  1 
ATOM 880  C C   . GLU B 2 13  ? 159.164 110.180 100.508 1.00 133.68 ? 13  GLU H C   1 
ATOM 881  O O   . GLU B 2 13  ? 158.043 109.870 100.097 1.00 133.68 ? 13  GLU H O   1 
ATOM 882  C CB  . GLU B 2 13  ? 158.988 109.900 102.991 1.00 133.68 ? 13  GLU H CB  1 
ATOM 883  C CG  . GLU B 2 13  ? 159.321 110.439 104.370 1.00 133.68 ? 13  GLU H CG  1 
ATOM 884  C CD  . GLU B 2 13  ? 160.811 110.595 104.589 1.00 133.68 ? 13  GLU H CD  1 
ATOM 885  O OE1 . GLU B 2 13  ? 161.585 109.799 104.017 1.00 133.68 ? 13  GLU H OE1 1 
ATOM 886  O OE2 . GLU B 2 13  ? 161.209 111.515 105.332 1.00 133.68 ? 13  GLU H OE2 1 
ATOM 887  N N   . LEU B 2 14  ? 160.279 109.948 99.816  1.00 137.03 ? 14  LEU H N   1 
ATOM 888  C CA  . LEU B 2 14  ? 160.264 109.378 98.475  1.00 137.03 ? 14  LEU H CA  1 
ATOM 889  C C   . LEU B 2 14  ? 161.001 108.044 98.398  1.00 137.03 ? 14  LEU H C   1 
ATOM 890  O O   . LEU B 2 14  ? 161.311 107.578 97.296  1.00 137.03 ? 14  LEU H O   1 
ATOM 891  C CB  . LEU B 2 14  ? 160.860 110.381 97.482  1.00 137.03 ? 14  LEU H CB  1 
ATOM 892  C CG  . LEU B 2 14  ? 160.523 110.245 95.994  1.00 137.03 ? 14  LEU H CG  1 
ATOM 893  C CD1 . LEU B 2 14  ? 159.181 110.889 95.683  1.00 137.03 ? 14  LEU H CD1 1 
ATOM 894  C CD2 . LEU B 2 14  ? 161.624 110.856 95.141  1.00 137.03 ? 14  LEU H CD2 1 
ATOM 895  N N   . VAL B 2 15  ? 161.284 107.413 99.540  1.00 139.63 ? 15  VAL H N   1 
ATOM 896  C CA  . VAL B 2 15  ? 162.021 106.157 99.527  1.00 139.63 ? 15  VAL H CA  1 
ATOM 897  C C   . VAL B 2 15  ? 161.188 105.073 98.842  1.00 139.63 ? 15  VAL H C   1 
ATOM 898  O O   . VAL B 2 15  ? 159.952 105.067 98.906  1.00 139.63 ? 15  VAL H O   1 
ATOM 899  C CB  . VAL B 2 15  ? 162.413 105.745 100.957 1.00 139.63 ? 15  VAL H CB  1 
ATOM 900  C CG1 . VAL B 2 15  ? 161.177 105.444 101.794 1.00 139.63 ? 15  VAL H CG1 1 
ATOM 901  C CG2 . VAL B 2 15  ? 163.370 104.559 100.942 1.00 139.63 ? 15  VAL H CG2 1 
ATOM 902  N N   . LYS B 2 16  ? 161.875 104.158 98.161  1.00 141.94 ? 16  LYS H N   1 
ATOM 903  C CA  . LYS B 2 16  ? 161.237 103.081 97.422  1.00 141.94 ? 16  LYS H CA  1 
ATOM 904  C C   . LYS B 2 16  ? 161.485 101.748 98.116  1.00 141.94 ? 16  LYS H C   1 
ATOM 905  O O   . LYS B 2 16  ? 162.255 101.655 99.077  1.00 141.94 ? 16  LYS H O   1 
ATOM 906  C CB  . LYS B 2 16  ? 161.747 103.012 95.976  1.00 141.94 ? 16  LYS H CB  1 
ATOM 907  C CG  . LYS B 2 16  ? 163.214 102.634 95.848  1.00 141.94 ? 16  LYS H CG  1 
ATOM 908  C CD  . LYS B 2 16  ? 163.625 102.507 94.389  1.00 141.94 ? 16  LYS H CD  1 
ATOM 909  C CE  . LYS B 2 16  ? 163.715 103.868 93.718  1.00 141.94 ? 16  LYS H CE  1 
ATOM 910  N NZ  . LYS B 2 16  ? 164.217 103.768 92.320  1.00 141.94 ? 16  LYS H NZ  1 
ATOM 911  N N   . SER B 2 17  ? 160.791 100.720 97.620  1.00 141.01 ? 17  SER H N   1 
ATOM 912  C CA  . SER B 2 17  ? 160.905 99.340  98.087  1.00 141.01 ? 17  SER H CA  1 
ATOM 913  C C   . SER B 2 17  ? 160.348 99.176  99.496  1.00 141.01 ? 17  SER H C   1 
ATOM 914  O O   . SER B 2 17  ? 160.127 100.161 100.208 1.00 141.01 ? 17  SER H O   1 
ATOM 915  C CB  . SER B 2 17  ? 162.359 98.858  98.027  1.00 141.01 ? 17  SER H CB  1 
ATOM 916  O OG  . SER B 2 17  ? 163.127 99.407  99.084  1.00 141.01 ? 17  SER H OG  1 
ATOM 917  N N   . GLY B 2 18  ? 160.111 97.932  99.902  1.00 139.05 ? 18  GLY H N   1 
ATOM 918  C CA  . GLY B 2 18  ? 159.544 97.653  101.205 1.00 139.05 ? 18  GLY H CA  1 
ATOM 919  C C   . GLY B 2 18  ? 160.567 97.391  102.289 1.00 139.05 ? 18  GLY H C   1 
ATOM 920  O O   . GLY B 2 18  ? 160.690 96.258  102.764 1.00 139.05 ? 18  GLY H O   1 
ATOM 921  N N   . THR B 2 19  ? 161.313 98.423  102.692 1.00 137.58 ? 19  THR H N   1 
ATOM 922  C CA  . THR B 2 19  ? 162.282 98.275  103.763 1.00 137.58 ? 19  THR H CA  1 
ATOM 923  C C   . THR B 2 19  ? 161.661 98.813  105.038 1.00 137.58 ? 19  THR H C   1 
ATOM 924  O O   . THR B 2 19  ? 161.465 98.044  106.001 1.00 137.58 ? 19  THR H O   1 
ATOM 925  C CB  . THR B 2 19  ? 163.599 98.971  103.394 1.00 137.58 ? 19  THR H CB  1 
ATOM 926  O OG1 . THR B 2 19  ? 163.364 100.372 103.208 1.00 137.58 ? 19  THR H OG1 1 
ATOM 927  C CG2 . THR B 2 19  ? 164.169 98.386  102.113 1.00 137.58 ? 19  THR H CG2 1 
ATOM 928  N N   . SER B 2 20  ? 161.294 100.091 105.098 1.00 135.11 ? 20  SER H N   1 
ATOM 929  C CA  . SER B 2 20  ? 160.683 100.709 106.274 1.00 135.11 ? 20  SER H CA  1 
ATOM 930  C C   . SER B 2 20  ? 160.398 102.169 105.941 1.00 135.11 ? 20  SER H C   1 
ATOM 931  O O   . SER B 2 20  ? 160.777 102.671 104.878 1.00 135.11 ? 20  SER H O   1 
ATOM 932  C CB  . SER B 2 20  ? 161.573 100.597 107.515 1.00 135.11 ? 20  SER H CB  1 
ATOM 933  O OG  . SER B 2 20  ? 161.429 99.327  108.127 1.00 135.11 ? 20  SER H OG  1 
ATOM 934  N N   . VAL B 2 21  ? 159.722 102.848 106.867 1.00 131.04 ? 21  VAL H N   1 
ATOM 935  C CA  . VAL B 2 21  ? 159.462 104.280 106.766 1.00 131.04 ? 21  VAL H CA  1 
ATOM 936  C C   . VAL B 2 21  ? 159.121 104.783 108.163 1.00 131.04 ? 21  VAL H C   1 
ATOM 937  O O   . VAL B 2 21  ? 158.725 103.998 109.032 1.00 131.04 ? 21  VAL H O   1 
ATOM 938  C CB  . VAL B 2 21  ? 158.332 104.578 105.761 1.00 131.04 ? 21  VAL H CB  1 
ATOM 939  C CG1 . VAL B 2 21  ? 157.008 104.026 106.267 1.00 131.04 ? 21  VAL H CG1 1 
ATOM 940  C CG2 . VAL B 2 21  ? 158.240 106.068 105.453 1.00 131.04 ? 21  VAL H CG2 1 
ATOM 941  N N   . LYS B 2 22  ? 159.277 106.092 108.400 1.00 125.34 ? 22  LYS H N   1 
ATOM 942  C CA  . LYS B 2 22  ? 158.972 106.660 109.715 1.00 125.34 ? 22  LYS H CA  1 
ATOM 943  C C   . LYS B 2 22  ? 158.301 108.020 109.496 1.00 125.34 ? 22  LYS H C   1 
ATOM 944  O O   . LYS B 2 22  ? 158.950 109.044 109.271 1.00 125.34 ? 22  LYS H O   1 
ATOM 945  C CB  . LYS B 2 22  ? 160.219 106.787 110.588 1.00 125.34 ? 22  LYS H CB  1 
ATOM 946  C CG  . LYS B 2 22  ? 159.990 107.534 111.892 1.00 125.34 ? 22  LYS H CG  1 
ATOM 947  C CD  . LYS B 2 22  ? 161.016 107.140 112.939 1.00 125.34 ? 22  LYS H CD  1 
ATOM 948  C CE  . LYS B 2 22  ? 160.930 105.661 113.263 1.00 125.34 ? 22  LYS H CE  1 
ATOM 949  N NZ  . LYS B 2 22  ? 159.672 105.334 113.983 1.00 125.34 ? 22  LYS H NZ  1 
ATOM 950  N N   . LEU B 2 23  ? 156.974 108.020 109.562 1.00 120.60 ? 23  LEU H N   1 
ATOM 951  C CA  . LEU B 2 23  ? 156.212 109.254 109.466 1.00 120.60 ? 23  LEU H CA  1 
ATOM 952  C C   . LEU B 2 23  ? 155.911 109.784 110.862 1.00 120.60 ? 23  LEU H C   1 
ATOM 953  O O   . LEU B 2 23  ? 155.706 109.018 111.805 1.00 120.60 ? 23  LEU H O   1 
ATOM 954  C CB  . LEU B 2 23  ? 154.911 109.025 108.701 1.00 120.60 ? 23  LEU H CB  1 
ATOM 955  C CG  . LEU B 2 23  ? 155.080 108.655 107.227 1.00 120.60 ? 23  LEU H CG  1 
ATOM 956  C CD1 . LEU B 2 23  ? 153.738 108.318 106.600 1.00 120.60 ? 23  LEU H CD1 1 
ATOM 957  C CD2 . LEU B 2 23  ? 155.783 109.756 106.459 1.00 120.60 ? 23  LEU H CD2 1 
ATOM 958  N N   . SER B 2 24  ? 155.882 111.108 110.988 1.00 119.28 ? 24  SER H N   1 
ATOM 959  C CA  . SER B 2 24  ? 155.746 111.755 112.283 1.00 119.28 ? 24  SER H CA  1 
ATOM 960  C C   . SER B 2 24  ? 154.676 112.836 112.220 1.00 119.28 ? 24  SER H C   1 
ATOM 961  O O   . SER B 2 24  ? 154.282 113.297 111.145 1.00 119.28 ? 24  SER H O   1 
ATOM 962  C CB  . SER B 2 24  ? 157.078 112.358 112.748 1.00 119.28 ? 24  SER H CB  1 
ATOM 963  O OG  . SER B 2 24  ? 157.370 113.550 112.039 1.00 119.28 ? 24  SER H OG  1 
ATOM 964  N N   . CYS B 2 25  ? 154.207 113.238 113.402 1.00 117.06 ? 25  CYS H N   1 
ATOM 965  C CA  . CYS B 2 25  ? 153.181 114.273 113.523 1.00 117.06 ? 25  CYS H CA  1 
ATOM 966  C C   . CYS B 2 25  ? 153.427 115.002 114.841 1.00 117.06 ? 25  CYS H C   1 
ATOM 967  O O   . CYS B 2 25  ? 153.020 114.523 115.903 1.00 117.06 ? 25  CYS H O   1 
ATOM 968  C CB  . CYS B 2 25  ? 151.785 113.669 113.471 1.00 117.06 ? 25  CYS H CB  1 
ATOM 969  S SG  . CYS B 2 25  ? 150.447 114.872 113.359 1.00 117.06 ? 25  CYS H SG  1 
ATOM 970  N N   . LYS B 2 26  ? 154.091 116.153 114.765 1.00 121.12 ? 26  LYS H N   1 
ATOM 971  C CA  . LYS B 2 26  ? 154.428 116.937 115.951 1.00 121.12 ? 26  LYS H CA  1 
ATOM 972  C C   . LYS B 2 26  ? 153.203 117.786 116.275 1.00 121.12 ? 26  LYS H C   1 
ATOM 973  O O   . LYS B 2 26  ? 152.987 118.856 115.704 1.00 121.12 ? 26  LYS H O   1 
ATOM 974  C CB  . LYS B 2 26  ? 155.675 117.782 115.697 1.00 121.12 ? 26  LYS H CB  1 
ATOM 975  C CG  . LYS B 2 26  ? 155.985 118.928 116.680 1.00 121.12 ? 26  LYS H CG  1 
ATOM 976  C CD  . LYS B 2 26  ? 155.564 118.653 118.122 1.00 121.12 ? 26  LYS H CD  1 
ATOM 977  C CE  . LYS B 2 26  ? 156.287 119.572 119.091 1.00 121.12 ? 26  LYS H CE  1 
ATOM 978  N NZ  . LYS B 2 26  ? 155.940 119.271 120.507 1.00 121.12 ? 26  LYS H NZ  1 
ATOM 979  N N   . ALA B 2 27  ? 152.386 117.294 117.201 1.00 119.13 ? 27  ALA H N   1 
ATOM 980  C CA  . ALA B 2 27  ? 151.196 118.006 117.638 1.00 119.13 ? 27  ALA H CA  1 
ATOM 981  C C   . ALA B 2 27  ? 151.526 118.899 118.824 1.00 119.13 ? 27  ALA H C   1 
ATOM 982  O O   . ALA B 2 27  ? 152.288 118.514 119.715 1.00 119.13 ? 27  ALA H O   1 
ATOM 983  C CB  . ALA B 2 27  ? 150.087 117.023 118.015 1.00 119.13 ? 27  ALA H CB  1 
ATOM 984  N N   . SER B 2 28  ? 150.948 120.097 118.831 1.00 115.44 ? 28  SER H N   1 
ATOM 985  C CA  . SER B 2 28  ? 151.201 121.061 119.890 1.00 115.44 ? 28  SER H CA  1 
ATOM 986  C C   . SER B 2 28  ? 149.898 121.739 120.282 1.00 115.44 ? 28  SER H C   1 
ATOM 987  O O   . SER B 2 28  ? 148.937 121.782 119.512 1.00 115.44 ? 28  SER H O   1 
ATOM 988  C CB  . SER B 2 28  ? 152.236 122.109 119.463 1.00 115.44 ? 28  SER H CB  1 
ATOM 989  O OG  . SER B 2 28  ? 152.154 123.264 120.277 1.00 115.44 ? 28  SER H OG  1 
ATOM 990  N N   . GLY B 2 29  ? 149.877 122.269 121.502 1.00 112.24 ? 29  GLY H N   1 
ATOM 991  C CA  . GLY B 2 29  ? 148.730 122.994 121.999 1.00 112.24 ? 29  GLY H CA  1 
ATOM 992  C C   . GLY B 2 29  ? 147.680 122.159 122.695 1.00 112.24 ? 29  GLY H C   1 
ATOM 993  O O   . GLY B 2 29  ? 146.692 122.724 123.182 1.00 112.24 ? 29  GLY H O   1 
ATOM 994  N N   . TYR B 2 30  ? 147.850 120.841 122.760 1.00 107.58 ? 30  TYR H N   1 
ATOM 995  C CA  . TYR B 2 30  ? 146.873 119.994 123.426 1.00 107.58 ? 30  TYR H CA  1 
ATOM 996  C C   . TYR B 2 30  ? 147.584 118.813 124.068 1.00 107.58 ? 30  TYR H C   1 
ATOM 997  O O   . TYR B 2 30  ? 148.687 118.431 123.668 1.00 107.58 ? 30  TYR H O   1 
ATOM 998  C CB  . TYR B 2 30  ? 145.792 119.506 122.455 1.00 107.58 ? 30  TYR H CB  1 
ATOM 999  C CG  . TYR B 2 30  ? 146.101 118.185 121.788 1.00 107.58 ? 30  TYR H CG  1 
ATOM 1000 C CD1 . TYR B 2 30  ? 146.946 118.119 120.692 1.00 107.58 ? 30  TYR H CD1 1 
ATOM 1001 C CD2 . TYR B 2 30  ? 145.529 117.007 122.245 1.00 107.58 ? 30  TYR H CD2 1 
ATOM 1002 C CE1 . TYR B 2 30  ? 147.223 116.914 120.079 1.00 107.58 ? 30  TYR H CE1 1 
ATOM 1003 C CE2 . TYR B 2 30  ? 145.802 115.800 121.639 1.00 107.58 ? 30  TYR H CE2 1 
ATOM 1004 C CZ  . TYR B 2 30  ? 146.647 115.759 120.557 1.00 107.58 ? 30  TYR H CZ  1 
ATOM 1005 O OH  . TYR B 2 30  ? 146.918 114.554 119.952 1.00 107.58 ? 30  TYR H OH  1 
ATOM 1006 N N   . SER B 2 31  ? 146.932 118.237 125.071 1.00 109.24 ? 31  SER H N   1 
ATOM 1007 C CA  . SER B 2 31  ? 147.459 117.098 125.805 1.00 109.24 ? 31  SER H CA  1 
ATOM 1008 C C   . SER B 2 31  ? 146.655 115.844 125.485 1.00 109.24 ? 31  SER H C   1 
ATOM 1009 O O   . SER B 2 31  ? 145.465 115.909 125.168 1.00 109.24 ? 31  SER H O   1 
ATOM 1010 C CB  . SER B 2 31  ? 147.433 117.363 127.310 1.00 109.24 ? 31  SER H CB  1 
ATOM 1011 O OG  . SER B 2 31  ? 146.139 117.755 127.732 1.00 109.24 ? 31  SER H OG  1 
ATOM 1012 N N   . PHE B 2 32  ? 147.317 114.696 125.590 1.00 108.27 ? 32  PHE H N   1 
ATOM 1013 C CA  . PHE B 2 32  ? 146.723 113.412 125.242 1.00 108.27 ? 32  PHE H CA  1 
ATOM 1014 C C   . PHE B 2 32  ? 145.799 112.870 126.324 1.00 108.27 ? 32  PHE H C   1 
ATOM 1015 O O   . PHE B 2 32  ? 145.457 111.684 126.279 1.00 108.27 ? 32  PHE H O   1 
ATOM 1016 C CB  . PHE B 2 32  ? 147.823 112.385 124.962 1.00 108.27 ? 32  PHE H CB  1 
ATOM 1017 C CG  . PHE B 2 32  ? 148.613 112.660 123.717 1.00 108.27 ? 32  PHE H CG  1 
ATOM 1018 C CD1 . PHE B 2 32  ? 149.630 113.597 123.720 1.00 108.27 ? 32  PHE H CD1 1 
ATOM 1019 C CD2 . PHE B 2 32  ? 148.346 111.974 122.547 1.00 108.27 ? 32  PHE H CD2 1 
ATOM 1020 C CE1 . PHE B 2 32  ? 150.362 113.849 122.578 1.00 108.27 ? 32  PHE H CE1 1 
ATOM 1021 C CE2 . PHE B 2 32  ? 149.075 112.222 121.402 1.00 108.27 ? 32  PHE H CE2 1 
ATOM 1022 C CZ  . PHE B 2 32  ? 150.084 113.161 121.419 1.00 108.27 ? 32  PHE H CZ  1 
ATOM 1023 N N   . THR B 2 33  ? 145.386 113.698 127.286 1.00 103.52 ? 33  THR H N   1 
ATOM 1024 C CA  . THR B 2 33  ? 144.672 113.179 128.449 1.00 103.52 ? 33  THR H CA  1 
ATOM 1025 C C   . THR B 2 33  ? 143.324 112.576 128.067 1.00 103.52 ? 33  THR H C   1 
ATOM 1026 O O   . THR B 2 33  ? 142.910 111.561 128.639 1.00 103.52 ? 33  THR H O   1 
ATOM 1027 C CB  . THR B 2 33  ? 144.507 114.280 129.503 1.00 103.52 ? 33  THR H CB  1 
ATOM 1028 O OG1 . THR B 2 33  ? 143.955 113.721 130.701 1.00 103.52 ? 33  THR H OG1 1 
ATOM 1029 C CG2 . THR B 2 33  ? 143.616 115.413 129.003 1.00 103.52 ? 33  THR H CG2 1 
ATOM 1030 N N   . ASP B 2 34  ? 142.621 113.179 127.109 1.00 97.65  ? 34  ASP H N   1 
ATOM 1031 C CA  . ASP B 2 34  ? 141.307 112.676 126.727 1.00 97.65  ? 34  ASP H CA  1 
ATOM 1032 C C   . ASP B 2 34  ? 141.240 112.551 125.209 1.00 97.65  ? 34  ASP H C   1 
ATOM 1033 O O   . ASP B 2 34  ? 140.589 111.647 124.677 1.00 97.65  ? 34  ASP H O   1 
ATOM 1034 C CB  . ASP B 2 34  ? 140.221 113.613 127.273 1.00 97.65  ? 34  ASP H CB  1 
ATOM 1035 C CG  . ASP B 2 34  ? 138.827 113.292 126.757 1.00 97.65  ? 34  ASP H CG  1 
ATOM 1036 O OD1 . ASP B 2 34  ? 138.594 112.183 126.238 1.00 97.65  ? 34  ASP H OD1 1 
ATOM 1037 O OD2 . ASP B 2 34  ? 137.945 114.165 126.883 1.00 97.65  ? 34  ASP H OD2 1 
ATOM 1038 N N   . HIS B 2 35  ? 141.950 113.428 124.506 1.00 92.54  ? 35  HIS H N   1 
ATOM 1039 C CA  . HIS B 2 35  ? 141.855 113.489 123.057 1.00 92.54  ? 35  HIS H CA  1 
ATOM 1040 C C   . HIS B 2 35  ? 142.467 112.250 122.411 1.00 92.54  ? 35  HIS H C   1 
ATOM 1041 O O   . HIS B 2 35  ? 143.259 111.521 123.012 1.00 92.54  ? 35  HIS H O   1 
ATOM 1042 C CB  . HIS B 2 35  ? 142.547 114.743 122.530 1.00 92.54  ? 35  HIS H CB  1 
ATOM 1043 C CG  . HIS B 2 35  ? 142.050 116.011 123.148 1.00 92.54  ? 35  HIS H CG  1 
ATOM 1044 N ND1 . HIS B 2 35  ? 142.398 116.404 124.422 1.00 92.54  ? 35  HIS H ND1 1 
ATOM 1045 C CD2 . HIS B 2 35  ? 141.236 116.979 122.665 1.00 92.54  ? 35  HIS H CD2 1 
ATOM 1046 C CE1 . HIS B 2 35  ? 141.816 117.557 124.699 1.00 92.54  ? 35  HIS H CE1 1 
ATOM 1047 N NE2 . HIS B 2 35  ? 141.106 117.927 123.649 1.00 92.54  ? 35  HIS H NE2 1 
ATOM 1048 N N   . SER B 2 36  ? 142.080 112.020 121.160 1.00 90.86  ? 36  SER H N   1 
ATOM 1049 C CA  . SER B 2 36  ? 142.569 110.909 120.359 1.00 90.86  ? 36  SER H CA  1 
ATOM 1050 C C   . SER B 2 36  ? 143.234 111.454 119.105 1.00 90.86  ? 36  SER H C   1 
ATOM 1051 O O   . SER B 2 36  ? 142.738 112.406 118.496 1.00 90.86  ? 36  SER H O   1 
ATOM 1052 C CB  . SER B 2 36  ? 141.432 109.968 119.972 1.00 90.86  ? 36  SER H CB  1 
ATOM 1053 O OG  . SER B 2 36  ? 140.402 110.672 119.304 1.00 90.86  ? 36  SER H OG  1 
ATOM 1054 N N   . LEU B 2 37  ? 144.355 110.854 118.722 1.00 93.34  ? 37  LEU H N   1 
ATOM 1055 C CA  . LEU B 2 37  ? 145.108 111.277 117.543 1.00 93.34  ? 37  LEU H CA  1 
ATOM 1056 C C   . LEU B 2 37  ? 144.938 110.211 116.465 1.00 93.34  ? 37  LEU H C   1 
ATOM 1057 O O   . LEU B 2 37  ? 145.619 109.184 116.482 1.00 93.34  ? 37  LEU H O   1 
ATOM 1058 C CB  . LEU B 2 37  ? 146.575 111.508 117.890 1.00 93.34  ? 37  LEU H CB  1 
ATOM 1059 C CG  . LEU B 2 37  ? 147.433 112.212 116.838 1.00 93.34  ? 37  LEU H CG  1 
ATOM 1060 C CD1 . LEU B 2 37  ? 148.493 113.061 117.510 1.00 93.34  ? 37  LEU H CD1 1 
ATOM 1061 C CD2 . LEU B 2 37  ? 148.084 111.210 115.903 1.00 93.34  ? 37  LEU H CD2 1 
ATOM 1062 N N   . HIS B 2 38  ? 144.030 110.465 115.527 1.00 91.71  ? 38  HIS H N   1 
ATOM 1063 C CA  . HIS B 2 38  ? 143.760 109.547 114.434 1.00 91.71  ? 38  HIS H CA  1 
ATOM 1064 C C   . HIS B 2 38  ? 144.857 109.637 113.375 1.00 91.71  ? 38  HIS H C   1 
ATOM 1065 O O   . HIS B 2 38  ? 145.680 110.554 113.370 1.00 91.71  ? 38  HIS H O   1 
ATOM 1066 C CB  . HIS B 2 38  ? 142.398 109.848 113.818 1.00 91.71  ? 38  HIS H CB  1 
ATOM 1067 C CG  . HIS B 2 38  ? 141.287 109.907 114.817 1.00 91.71  ? 38  HIS H CG  1 
ATOM 1068 N ND1 . HIS B 2 38  ? 140.894 108.816 115.560 1.00 91.71  ? 38  HIS H ND1 1 
ATOM 1069 C CD2 . HIS B 2 38  ? 140.506 110.936 115.219 1.00 91.71  ? 38  HIS H CD2 1 
ATOM 1070 C CE1 . HIS B 2 38  ? 139.904 109.165 116.361 1.00 91.71  ? 38  HIS H CE1 1 
ATOM 1071 N NE2 . HIS B 2 38  ? 139.649 110.446 116.174 1.00 91.71  ? 38  HIS H NE2 1 
ATOM 1072 N N   . TRP B 2 39  ? 144.866 108.662 112.471 1.00 101.02 ? 39  TRP H N   1 
ATOM 1073 C CA  . TRP B 2 39  ? 145.867 108.588 111.409 1.00 101.02 ? 39  TRP H CA  1 
ATOM 1074 C C   . TRP B 2 39  ? 145.212 108.242 110.076 1.00 101.02 ? 39  TRP H C   1 
ATOM 1075 O O   . TRP B 2 39  ? 145.626 107.319 109.376 1.00 101.02 ? 39  TRP H O   1 
ATOM 1076 C CB  . TRP B 2 39  ? 146.962 107.586 111.759 1.00 101.02 ? 39  TRP H CB  1 
ATOM 1077 C CG  . TRP B 2 39  ? 148.106 108.205 112.484 1.00 101.02 ? 39  TRP H CG  1 
ATOM 1078 C CD1 . TRP B 2 39  ? 148.411 108.067 113.803 1.00 101.02 ? 39  TRP H CD1 1 
ATOM 1079 C CD2 . TRP B 2 39  ? 149.100 109.070 111.929 1.00 101.02 ? 39  TRP H CD2 1 
ATOM 1080 N NE1 . TRP B 2 39  ? 149.538 108.789 114.105 1.00 101.02 ? 39  TRP H NE1 1 
ATOM 1081 C CE2 . TRP B 2 39  ? 149.980 109.414 112.971 1.00 101.02 ? 39  TRP H CE2 1 
ATOM 1082 C CE3 . TRP B 2 39  ? 149.334 109.584 110.652 1.00 101.02 ? 39  TRP H CE3 1 
ATOM 1083 C CZ2 . TRP B 2 39  ? 151.074 110.249 112.775 1.00 101.02 ? 39  TRP H CZ2 1 
ATOM 1084 C CZ3 . TRP B 2 39  ? 150.420 110.411 110.460 1.00 101.02 ? 39  TRP H CZ3 1 
ATOM 1085 C CH2 . TRP B 2 39  ? 151.276 110.737 111.515 1.00 101.02 ? 39  TRP H CH2 1 
ATOM 1086 N N   . VAL B 2 40  ? 144.164 108.987 109.715 1.00 97.57  ? 40  VAL H N   1 
ATOM 1087 C CA  . VAL B 2 40  ? 143.438 108.704 108.484 1.00 97.57  ? 40  VAL H CA  1 
ATOM 1088 C C   . VAL B 2 40  ? 144.362 108.806 107.277 1.00 97.57  ? 40  VAL H C   1 
ATOM 1089 O O   . VAL B 2 40  ? 145.228 109.687 107.197 1.00 97.57  ? 40  VAL H O   1 
ATOM 1090 C CB  . VAL B 2 40  ? 142.233 109.651 108.350 1.00 97.57  ? 40  VAL H CB  1 
ATOM 1091 C CG1 . VAL B 2 40  ? 142.689 111.088 108.201 1.00 97.57  ? 40  VAL H CG1 1 
ATOM 1092 C CG2 . VAL B 2 40  ? 141.373 109.247 107.170 1.00 97.57  ? 40  VAL H CG2 1 
ATOM 1093 N N   . LYS B 2 41  ? 144.196 107.876 106.340 1.00 104.58 ? 41  LYS H N   1 
ATOM 1094 C CA  . LYS B 2 41  ? 144.942 107.854 105.090 1.00 104.58 ? 41  LYS H CA  1 
ATOM 1095 C C   . LYS B 2 41  ? 144.013 108.203 103.938 1.00 104.58 ? 41  LYS H C   1 
ATOM 1096 O O   . LYS B 2 41  ? 142.878 107.724 103.879 1.00 104.58 ? 41  LYS H O   1 
ATOM 1097 C CB  . LYS B 2 41  ? 145.571 106.482 104.841 1.00 104.58 ? 41  LYS H CB  1 
ATOM 1098 C CG  . LYS B 2 41  ? 146.373 106.404 103.554 1.00 104.58 ? 41  LYS H CG  1 
ATOM 1099 C CD  . LYS B 2 41  ? 146.896 105.002 103.296 1.00 104.58 ? 41  LYS H CD  1 
ATOM 1100 C CE  . LYS B 2 41  ? 145.912 104.182 102.485 1.00 104.58 ? 41  LYS H CE  1 
ATOM 1101 N NZ  . LYS B 2 41  ? 146.532 102.933 101.965 1.00 104.58 ? 41  LYS H NZ  1 
ATOM 1102 N N   . GLN B 2 42  ? 144.501 109.032 103.017 1.00 108.56 ? 42  GLN H N   1 
ATOM 1103 C CA  . GLN B 2 42  ? 143.693 109.502 101.903 1.00 108.56 ? 42  GLN H CA  1 
ATOM 1104 C C   . GLN B 2 42  ? 143.903 108.694 100.632 1.00 108.56 ? 42  GLN H C   1 
ATOM 1105 O O   . GLN B 2 42  ? 143.058 108.755 99.733  1.00 108.56 ? 42  GLN H O   1 
ATOM 1106 C CB  . GLN B 2 42  ? 143.979 110.984 101.634 1.00 108.56 ? 42  GLN H CB  1 
ATOM 1107 C CG  . GLN B 2 42  ? 142.812 111.744 101.018 1.00 108.56 ? 42  GLN H CG  1 
ATOM 1108 C CD  . GLN B 2 42  ? 142.865 111.792 99.507  1.00 108.56 ? 42  GLN H CD  1 
ATOM 1109 O OE1 . GLN B 2 42  ? 143.814 111.311 98.892  1.00 108.56 ? 42  GLN H OE1 1 
ATOM 1110 N NE2 . GLN B 2 42  ? 141.839 112.374 98.898  1.00 108.56 ? 42  GLN H NE2 1 
ATOM 1111 N N   . SER B 2 43  ? 144.988 107.924 100.546 1.00 113.14 ? 43  SER H N   1 
ATOM 1112 C CA  . SER B 2 43  ? 145.387 107.206 99.328  1.00 113.14 ? 43  SER H CA  1 
ATOM 1113 C C   . SER B 2 43  ? 145.423 108.228 98.192  1.00 113.14 ? 43  SER H C   1 
ATOM 1114 O O   . SER B 2 43  ? 145.737 109.399 98.443  1.00 113.14 ? 43  SER H O   1 
ATOM 1115 C CB  . SER B 2 43  ? 144.465 106.016 99.111  1.00 113.14 ? 43  SER H CB  1 
ATOM 1116 O OG  . SER B 2 43  ? 143.232 106.429 98.549  1.00 113.14 ? 43  SER H OG  1 
ATOM 1117 N N   . HIS B 2 44  ? 145.085 107.856 96.961  1.00 117.26 ? 44  HIS H N   1 
ATOM 1118 C CA  . HIS B 2 44  ? 145.032 108.820 95.867  1.00 117.26 ? 44  HIS H CA  1 
ATOM 1119 C C   . HIS B 2 44  ? 143.725 108.600 95.123  1.00 117.26 ? 44  HIS H C   1 
ATOM 1120 O O   . HIS B 2 44  ? 143.405 107.466 94.753  1.00 117.26 ? 44  HIS H O   1 
ATOM 1121 C CB  . HIS B 2 44  ? 146.226 108.674 94.931  1.00 117.26 ? 44  HIS H CB  1 
ATOM 1122 C CG  . HIS B 2 44  ? 146.342 109.779 93.928  1.00 117.26 ? 44  HIS H CG  1 
ATOM 1123 N ND1 . HIS B 2 44  ? 145.612 109.803 92.759  1.00 117.26 ? 44  HIS H ND1 1 
ATOM 1124 C CD2 . HIS B 2 44  ? 147.102 110.899 93.920  1.00 117.26 ? 44  HIS H CD2 1 
ATOM 1125 C CE1 . HIS B 2 44  ? 145.918 110.890 92.074  1.00 117.26 ? 44  HIS H CE1 1 
ATOM 1126 N NE2 . HIS B 2 44  ? 146.820 111.572 92.757  1.00 117.26 ? 44  HIS H NE2 1 
ATOM 1127 N N   . GLY B 2 45  ? 142.977 109.675 94.903  1.00 113.60 ? 45  GLY H N   1 
ATOM 1128 C CA  . GLY B 2 45  ? 141.683 109.545 94.270  1.00 113.60 ? 45  GLY H CA  1 
ATOM 1129 C C   . GLY B 2 45  ? 140.541 109.919 95.188  1.00 113.60 ? 45  GLY H C   1 
ATOM 1130 O O   . GLY B 2 45  ? 140.338 111.096 95.497  1.00 113.60 ? 45  GLY H O   1 
ATOM 1131 N N   . GLU B 2 46  ? 139.787 108.917 95.630  1.00 110.34 ? 46  GLU H N   1 
ATOM 1132 C CA  . GLU B 2 46  ? 138.554 109.134 96.368  1.00 110.34 ? 46  GLU H CA  1 
ATOM 1133 C C   . GLU B 2 46  ? 138.519 108.203 97.573  1.00 110.34 ? 46  GLU H C   1 
ATOM 1134 O O   . GLU B 2 46  ? 139.309 107.258 97.655  1.00 110.34 ? 46  GLU H O   1 
ATOM 1135 C CB  . GLU B 2 46  ? 137.345 108.897 95.445  1.00 110.34 ? 46  GLU H CB  1 
ATOM 1136 C CG  . GLU B 2 46  ? 135.985 109.279 96.003  1.00 110.34 ? 46  GLU H CG  1 
ATOM 1137 C CD  . GLU B 2 46  ? 134.870 109.064 94.998  1.00 110.34 ? 46  GLU H CD  1 
ATOM 1138 O OE1 . GLU B 2 46  ? 135.162 108.607 93.873  1.00 110.34 ? 46  GLU H OE1 1 
ATOM 1139 O OE2 . GLU B 2 46  ? 133.702 109.351 95.332  1.00 110.34 ? 46  GLU H OE2 1 
ATOM 1140 N N   . SER B 2 47  ? 137.861 108.744 98.581  1.00 108.30 ? 47  SER H N   1 
ATOM 1141 C CA  . SER B 2 47  ? 137.548 108.157 99.849  1.00 108.30 ? 47  SER H CA  1 
ATOM 1142 C C   . SER B 2 47  ? 138.674 107.855 100.771 1.00 108.30 ? 47  SER H C   1 
ATOM 1143 O O   . SER B 2 47  ? 139.135 106.750 100.799 1.00 108.30 ? 47  SER H O   1 
ATOM 1144 C CB  . SER B 2 47  ? 136.731 106.899 99.632  1.00 108.30 ? 47  SER H CB  1 
ATOM 1145 O OG  . SER B 2 47  ? 137.568 105.785 99.440  1.00 108.30 ? 47  SER H OG  1 
ATOM 1146 N N   . LEU B 2 48  ? 139.117 108.815 101.545 1.00 101.29 ? 48  LEU H N   1 
ATOM 1147 C CA  . LEU B 2 48  ? 140.161 108.504 102.467 1.00 101.29 ? 48  LEU H CA  1 
ATOM 1148 C C   . LEU B 2 48  ? 139.555 107.687 103.556 1.00 101.29 ? 48  LEU H C   1 
ATOM 1149 O O   . LEU B 2 48  ? 138.497 108.017 103.994 1.00 101.29 ? 48  LEU H O   1 
ATOM 1150 C CB  . LEU B 2 48  ? 140.775 109.761 102.988 1.00 101.29 ? 48  LEU H CB  1 
ATOM 1151 C CG  . LEU B 2 48  ? 139.883 110.799 103.591 1.00 101.29 ? 48  LEU H CG  1 
ATOM 1152 C CD1 . LEU B 2 48  ? 140.753 111.930 104.094 1.00 101.29 ? 48  LEU H CD1 1 
ATOM 1153 C CD2 . LEU B 2 48  ? 138.902 111.320 102.580 1.00 101.29 ? 48  LEU H CD2 1 
ATOM 1154 N N   . GLU B 2 49  ? 140.241 106.655 104.021 1.00 102.49 ? 49  GLU H N   1 
ATOM 1155 C CA  . GLU B 2 49  ? 139.763 105.736 105.041 1.00 102.49 ? 49  GLU H CA  1 
ATOM 1156 C C   . GLU B 2 49  ? 140.591 105.697 106.287 1.00 102.49 ? 49  GLU H C   1 
ATOM 1157 O O   . GLU B 2 49  ? 141.754 105.628 106.210 1.00 102.49 ? 49  GLU H O   1 
ATOM 1158 C CB  . GLU B 2 49  ? 139.868 104.376 104.456 1.00 30.00  ? 49  GLU H CB  1 
ATOM 1159 C CG  . GLU B 2 49  ? 141.289 104.065 104.067 1.00 30.00  ? 49  GLU H CG  1 
ATOM 1160 C CD  . GLU B 2 49  ? 141.428 103.754 102.597 1.00 30.00  ? 49  GLU H CD  1 
ATOM 1161 O OE1 . GLU B 2 49  ? 142.259 102.918 102.217 1.00 30.00  ? 49  GLU H OE1 1 
ATOM 1162 O OE2 . GLU B 2 49  ? 140.706 104.355 101.805 1.00 30.00  ? 49  GLU H OE2 1 
ATOM 1163 N N   . TRP B 2 50  ? 139.999 105.558 107.448 1.00 95.03  ? 50  TRP H N   1 
ATOM 1164 C CA  . TRP B 2 50  ? 140.711 105.587 108.714 1.00 95.03  ? 50  TRP H CA  1 
ATOM 1165 C C   . TRP B 2 50  ? 141.746 104.506 108.891 1.00 95.03  ? 50  TRP H C   1 
ATOM 1166 O O   . TRP B 2 50  ? 141.581 103.483 108.352 1.00 95.03  ? 50  TRP H O   1 
ATOM 1167 C CB  . TRP B 2 50  ? 139.651 105.380 109.718 1.00 95.03  ? 50  TRP H CB  1 
ATOM 1168 C CG  . TRP B 2 50  ? 139.996 105.361 111.061 1.00 95.03  ? 50  TRP H CG  1 
ATOM 1169 C CD1 . TRP B 2 50  ? 140.315 106.376 111.770 1.00 95.03  ? 50  TRP H CD1 1 
ATOM 1170 C CD2 . TRP B 2 50  ? 139.981 104.249 111.925 1.00 95.03  ? 50  TRP H CD2 1 
ATOM 1171 N NE1 . TRP B 2 50  ? 140.549 106.016 113.036 1.00 95.03  ? 50  TRP H NE1 1 
ATOM 1172 C CE2 . TRP B 2 50  ? 140.336 104.692 113.150 1.00 95.03  ? 50  TRP H CE2 1 
ATOM 1173 C CE3 . TRP B 2 50  ? 139.707 102.913 111.765 1.00 95.03  ? 50  TRP H CE3 1 
ATOM 1174 C CZ2 . TRP B 2 50  ? 140.410 103.896 114.206 1.00 95.03  ? 50  TRP H CZ2 1 
ATOM 1175 C CZ3 . TRP B 2 50  ? 139.790 102.116 112.814 1.00 95.03  ? 50  TRP H CZ3 1 
ATOM 1176 C CH2 . TRP B 2 50  ? 140.141 102.598 114.018 1.00 95.03  ? 50  TRP H CH2 1 
ATOM 1177 N N   . ILE B 2 51  ? 142.830 104.747 109.637 1.00 97.29  ? 51  ILE H N   1 
ATOM 1178 C CA  . ILE B 2 51  ? 143.945 103.824 109.865 1.00 97.29  ? 51  ILE H CA  1 
ATOM 1179 C C   . ILE B 2 51  ? 144.259 103.504 111.315 1.00 97.29  ? 51  ILE H C   1 
ATOM 1180 O O   . ILE B 2 51  ? 145.081 102.702 111.594 1.00 97.29  ? 51  ILE H O   1 
ATOM 1181 C CB  . ILE B 2 51  ? 145.178 104.388 109.172 1.00 97.29  ? 51  ILE H CB  1 
ATOM 1182 C CG1 . ILE B 2 51  ? 145.133 103.976 107.737 1.00 97.29  ? 51  ILE H CG1 1 
ATOM 1183 C CG2 . ILE B 2 51  ? 146.484 103.802 109.613 1.00 97.29  ? 51  ILE H CG2 1 
ATOM 1184 C CD1 . ILE B 2 51  ? 145.322 102.487 107.545 1.00 97.29  ? 51  ILE H CD1 1 
ATOM 1185 N N   . GLY B 2 52  ? 143.577 104.129 112.248 1.00 96.84  ? 52  GLY H N   1 
ATOM 1186 C CA  . GLY B 2 52  ? 143.748 103.884 113.667 1.00 96.84  ? 52  GLY H CA  1 
ATOM 1187 C C   . GLY B 2 52  ? 143.973 105.184 114.411 1.00 96.84  ? 52  GLY H C   1 
ATOM 1188 O O   . GLY B 2 52  ? 144.053 106.258 113.822 1.00 96.84  ? 52  GLY H O   1 
ATOM 1189 N N   . TYR B 2 53  ? 144.074 105.062 115.729 1.00 97.69  ? 53  TYR H N   1 
ATOM 1190 C CA  . TYR B 2 53  ? 144.344 106.226 116.564 1.00 97.69  ? 53  TYR H CA  1 
ATOM 1191 C C   . TYR B 2 53  ? 145.143 105.781 117.784 1.00 97.69  ? 53  TYR H C   1 
ATOM 1192 O O   . TYR B 2 53  ? 145.704 104.681 117.810 1.00 97.69  ? 53  TYR H O   1 
ATOM 1193 C CB  . TYR B 2 53  ? 143.044 106.942 116.969 1.00 97.69  ? 53  TYR H CB  1 
ATOM 1194 C CG  . TYR B 2 53  ? 142.002 106.068 117.629 1.00 97.69  ? 53  TYR H CG  1 
ATOM 1195 C CD1 . TYR B 2 53  ? 142.096 105.739 118.972 1.00 97.69  ? 53  TYR H CD1 1 
ATOM 1196 C CD2 . TYR B 2 53  ? 140.905 105.612 116.923 1.00 97.69  ? 53  TYR H CD2 1 
ATOM 1197 C CE1 . TYR B 2 53  ? 141.142 104.954 119.582 1.00 97.69  ? 53  TYR H CE1 1 
ATOM 1198 C CE2 . TYR B 2 53  ? 139.945 104.825 117.524 1.00 97.69  ? 53  TYR H CE2 1 
ATOM 1199 C CZ  . TYR B 2 53  ? 140.069 104.500 118.853 1.00 97.69  ? 53  TYR H CZ  1 
ATOM 1200 O OH  . TYR B 2 53  ? 139.114 103.719 119.457 1.00 97.69  ? 53  TYR H OH  1 
ATOM 1201 N N   . PHE B 2 54  ? 145.192 106.647 118.794 1.00 101.48 ? 54  PHE H N   1 
ATOM 1202 C CA  . PHE B 2 54  ? 145.890 106.364 120.044 1.00 101.48 ? 54  PHE H CA  1 
ATOM 1203 C C   . PHE B 2 54  ? 145.145 107.093 121.154 1.00 101.48 ? 54  PHE H C   1 
ATOM 1204 O O   . PHE B 2 54  ? 145.295 108.309 121.304 1.00 101.48 ? 54  PHE H O   1 
ATOM 1205 C CB  . PHE B 2 54  ? 147.348 106.809 119.967 1.00 101.48 ? 54  PHE H CB  1 
ATOM 1206 C CG  . PHE B 2 54  ? 148.088 106.707 121.270 1.00 101.48 ? 54  PHE H CG  1 
ATOM 1207 C CD1 . PHE B 2 54  ? 148.674 105.517 121.655 1.00 101.48 ? 54  PHE H CD1 1 
ATOM 1208 C CD2 . PHE B 2 54  ? 148.216 107.809 122.099 1.00 101.48 ? 54  PHE H CD2 1 
ATOM 1209 C CE1 . PHE B 2 54  ? 149.359 105.420 122.848 1.00 101.48 ? 54  PHE H CE1 1 
ATOM 1210 C CE2 . PHE B 2 54  ? 148.900 107.718 123.293 1.00 101.48 ? 54  PHE H CE2 1 
ATOM 1211 C CZ  . PHE B 2 54  ? 149.473 106.523 123.668 1.00 101.48 ? 54  PHE H CZ  1 
ATOM 1212 N N   . SER B 2 55  ? 144.339 106.360 121.917 1.00 101.00 ? 55  SER H N   1 
ATOM 1213 C CA  . SER B 2 55  ? 143.568 106.924 123.019 1.00 101.00 ? 55  SER H CA  1 
ATOM 1214 C C   . SER B 2 55  ? 144.012 106.285 124.326 1.00 101.00 ? 55  SER H C   1 
ATOM 1215 O O   . SER B 2 55  ? 143.786 105.079 124.525 1.00 101.00 ? 55  SER H O   1 
ATOM 1216 C CB  . SER B 2 55  ? 142.070 106.706 122.809 1.00 101.00 ? 55  SER H CB  1 
ATOM 1217 O OG  . SER B 2 55  ? 141.619 107.343 121.631 1.00 101.00 ? 55  SER H OG  1 
ATOM 1218 N N   . PRO B 2 56  ? 144.646 107.029 125.233 1.00 103.25 ? 56  PRO H N   1 
ATOM 1219 C CA  . PRO B 2 56  ? 145.041 106.430 126.519 1.00 103.25 ? 56  PRO H CA  1 
ATOM 1220 C C   . PRO B 2 56  ? 143.872 105.885 127.318 1.00 103.25 ? 56  PRO H C   1 
ATOM 1221 O O   . PRO B 2 56  ? 144.032 104.880 128.023 1.00 103.25 ? 56  PRO H O   1 
ATOM 1222 C CB  . PRO B 2 56  ? 145.734 107.583 127.258 1.00 103.25 ? 56  PRO H CB  1 
ATOM 1223 C CG  . PRO B 2 56  ? 146.043 108.602 126.235 1.00 103.25 ? 56  PRO H CG  1 
ATOM 1224 C CD  . PRO B 2 56  ? 145.166 108.392 125.048 1.00 103.25 ? 56  PRO H CD  1 
ATOM 1225 N N   . ASN B 2 57  ? 142.702 106.511 127.233 1.00 102.59 ? 57  ASN H N   1 
ATOM 1226 C CA  . ASN B 2 57  ? 141.532 106.065 127.977 1.00 102.59 ? 57  ASN H CA  1 
ATOM 1227 C C   . ASN B 2 57  ? 140.749 104.972 127.263 1.00 102.59 ? 57  ASN H C   1 
ATOM 1228 O O   . ASN B 2 57  ? 139.828 104.404 127.857 1.00 102.59 ? 57  ASN H O   1 
ATOM 1229 C CB  . ASN B 2 57  ? 140.609 107.252 128.264 1.00 102.59 ? 57  ASN H CB  1 
ATOM 1230 C CG  . ASN B 2 57  ? 141.242 108.269 129.185 1.00 102.59 ? 57  ASN H CG  1 
ATOM 1231 O OD1 . ASN B 2 57  ? 142.460 108.288 129.362 1.00 102.59 ? 57  ASN H OD1 1 
ATOM 1232 N ND2 . ASN B 2 57  ? 140.419 109.123 129.779 1.00 102.59 ? 57  ASN H ND2 1 
ATOM 1233 N N   . ASN B 2 58  ? 141.086 104.665 126.010 1.00 101.81 ? 58  ASN H N   1 
ATOM 1234 C CA  . ASN B 2 58  ? 140.404 103.621 125.255 1.00 101.81 ? 58  ASN H CA  1 
ATOM 1235 C C   . ASN B 2 58  ? 141.343 102.500 124.829 1.00 101.81 ? 58  ASN H C   1 
ATOM 1236 O O   . ASN B 2 58  ? 140.922 101.599 124.095 1.00 101.81 ? 58  ASN H O   1 
ATOM 1237 C CB  . ASN B 2 58  ? 139.710 104.216 124.026 1.00 101.81 ? 58  ASN H CB  1 
ATOM 1238 C CG  . ASN B 2 58  ? 138.884 105.442 124.360 1.00 101.81 ? 58  ASN H CG  1 
ATOM 1239 O OD1 . ASN B 2 58  ? 138.419 105.603 125.487 1.00 101.81 ? 58  ASN H OD1 1 
ATOM 1240 N ND2 . ASN B 2 58  ? 138.699 106.315 123.379 1.00 101.81 ? 58  ASN H ND2 1 
ATOM 1241 N N   . GLY B 2 59  ? 142.599 102.530 125.266 1.00 104.41 ? 59  GLY H N   1 
ATOM 1242 C CA  . GLY B 2 59  ? 143.547 101.490 124.922 1.00 104.41 ? 59  GLY H CA  1 
ATOM 1243 C C   . GLY B 2 59  ? 144.744 101.993 124.143 1.00 104.41 ? 59  GLY H C   1 
ATOM 1244 O O   . GLY B 2 59  ? 145.877 101.576 124.397 1.00 104.41 ? 59  GLY H O   1 
ATOM 1245 N N   . GLY B 2 60  ? 144.508 102.891 123.190 1.00 104.48 ? 60  GLY H N   1 
ATOM 1246 C CA  . GLY B 2 60  ? 145.598 103.465 122.428 1.00 104.48 ? 60  GLY H CA  1 
ATOM 1247 C C   . GLY B 2 60  ? 146.201 102.566 121.376 1.00 104.48 ? 60  GLY H C   1 
ATOM 1248 O O   . GLY B 2 60  ? 147.234 102.919 120.801 1.00 104.48 ? 60  GLY H O   1 
ATOM 1249 N N   . THR B 2 61  ? 145.594 101.414 121.103 1.00 107.74 ? 61  THR H N   1 
ATOM 1250 C CA  . THR B 2 61  ? 146.139 100.496 120.113 1.00 107.74 ? 61  THR H CA  1 
ATOM 1251 C C   . THR B 2 61  ? 145.020 99.930  119.242 1.00 107.74 ? 61  THR H C   1 
ATOM 1252 O O   . THR B 2 61  ? 145.083 98.776  118.804 1.00 107.74 ? 61  THR H O   1 
ATOM 1253 C CB  . THR B 2 61  ? 146.933 99.375  120.794 1.00 107.74 ? 61  THR H CB  1 
ATOM 1254 O OG1 . THR B 2 61  ? 147.736 99.938  121.838 1.00 107.74 ? 61  THR H OG1 1 
ATOM 1255 C CG2 . THR B 2 61  ? 147.880 98.699  119.805 1.00 107.74 ? 61  THR H CG2 1 
ATOM 1256 N N   . ILE B 2 62  ? 143.983 100.722 118.997 1.00 102.69 ? 62  ILE H N   1 
ATOM 1257 C CA  . ILE B 2 62  ? 142.880 100.291 118.146 1.00 102.69 ? 62  ILE H CA  1 
ATOM 1258 C C   . ILE B 2 62  ? 143.289 100.491 116.695 1.00 102.69 ? 62  ILE H C   1 
ATOM 1259 O O   . ILE B 2 62  ? 143.509 101.622 116.250 1.00 102.69 ? 62  ILE H O   1 
ATOM 1260 C CB  . ILE B 2 62  ? 141.589 101.056 118.471 1.00 102.69 ? 62  ILE H CB  1 
ATOM 1261 C CG1 . ILE B 2 62  ? 141.135 100.771 119.906 1.00 102.69 ? 62  ILE H CG1 1 
ATOM 1262 C CG2 . ILE B 2 62  ? 140.497 100.693 117.483 1.00 102.69 ? 62  ILE H CG2 1 
ATOM 1263 C CD1 . ILE B 2 62  ? 141.716 101.702 120.951 1.00 102.69 ? 62  ILE H CD1 1 
ATOM 1264 N N   . TYR B 2 63  ? 143.396 99.393  115.955 1.00 106.70 ? 63  TYR H N   1 
ATOM 1265 C CA  . TYR B 2 63  ? 143.842 99.416  114.572 1.00 106.70 ? 63  TYR H CA  1 
ATOM 1266 C C   . TYR B 2 63  ? 142.699 98.993  113.666 1.00 106.70 ? 63  TYR H C   1 
ATOM 1267 O O   . TYR B 2 63  ? 141.944 98.072  113.992 1.00 106.70 ? 63  TYR H O   1 
ATOM 1268 C CB  . TYR B 2 63  ? 145.039 98.486  114.357 1.00 106.70 ? 63  TYR H CB  1 
ATOM 1269 C CG  . TYR B 2 63  ? 146.358 99.044  114.837 1.00 106.70 ? 63  TYR H CG  1 
ATOM 1270 C CD1 . TYR B 2 63  ? 146.469 99.640  116.084 1.00 106.70 ? 63  TYR H CD1 1 
ATOM 1271 C CD2 . TYR B 2 63  ? 147.494 98.967  114.046 1.00 106.70 ? 63  TYR H CD2 1 
ATOM 1272 C CE1 . TYR B 2 63  ? 147.669 100.147 116.529 1.00 106.70 ? 63  TYR H CE1 1 
ATOM 1273 C CE2 . TYR B 2 63  ? 148.700 99.471  114.484 1.00 106.70 ? 63  TYR H CE2 1 
ATOM 1274 C CZ  . TYR B 2 63  ? 148.781 100.060 115.727 1.00 106.70 ? 63  TYR H CZ  1 
ATOM 1275 O OH  . TYR B 2 63  ? 149.978 100.567 116.174 1.00 106.70 ? 63  TYR H OH  1 
ATOM 1276 N N   . ASN B 2 64  ? 142.570 99.672  112.531 1.00 103.66 ? 64  ASN H N   1 
ATOM 1277 C CA  . ASN B 2 64  ? 141.577 99.281  111.542 1.00 103.66 ? 64  ASN H CA  1 
ATOM 1278 C C   . ASN B 2 64  ? 141.935 97.919  110.967 1.00 103.66 ? 64  ASN H C   1 
ATOM 1279 O O   . ASN B 2 64  ? 143.115 97.594  110.804 1.00 103.66 ? 64  ASN H O   1 
ATOM 1280 C CB  . ASN B 2 64  ? 141.497 100.320 110.426 1.00 103.66 ? 64  ASN H CB  1 
ATOM 1281 C CG  . ASN B 2 64  ? 140.407 100.010 109.422 1.00 103.66 ? 64  ASN H CG  1 
ATOM 1282 O OD1 . ASN B 2 64  ? 139.475 99.263  109.714 1.00 103.66 ? 64  ASN H OD1 1 
ATOM 1283 N ND2 . ASN B 2 64  ? 140.519 100.582 108.230 1.00 103.66 ? 64  ASN H ND2 1 
ATOM 1284 N N   . GLN B 2 65  ? 140.917 97.116  110.669 1.00 108.59 ? 65  GLN H N   1 
ATOM 1285 C CA  . GLN B 2 65  ? 141.154 95.852  109.989 1.00 108.59 ? 65  GLN H CA  1 
ATOM 1286 C C   . GLN B 2 65  ? 141.740 96.112  108.608 1.00 108.59 ? 65  GLN H C   1 
ATOM 1287 O O   . GLN B 2 65  ? 141.746 97.244  108.119 1.00 108.59 ? 65  GLN H O   1 
ATOM 1288 C CB  . GLN B 2 65  ? 139.859 95.047  109.879 1.00 108.59 ? 65  GLN H CB  1 
ATOM 1289 C CG  . GLN B 2 65  ? 138.991 95.084  111.129 1.00 108.59 ? 65  GLN H CG  1 
ATOM 1290 C CD  . GLN B 2 65  ? 139.770 94.812  112.405 1.00 108.59 ? 65  GLN H CD  1 
ATOM 1291 O OE1 . GLN B 2 65  ? 140.665 93.966  112.435 1.00 108.59 ? 65  GLN H OE1 1 
ATOM 1292 N NE2 . GLN B 2 65  ? 139.431 95.532  113.467 1.00 108.59 ? 65  GLN H NE2 1 
ATOM 1293 N N   . LYS B 2 66  ? 142.275 95.054  107.998 1.00 111.74 ? 66  LYS H N   1 
ATOM 1294 C CA  . LYS B 2 66  ? 142.994 95.041  106.723 1.00 111.74 ? 66  LYS H CA  1 
ATOM 1295 C C   . LYS B 2 66  ? 144.184 95.997  106.721 1.00 111.74 ? 66  LYS H C   1 
ATOM 1296 O O   . LYS B 2 66  ? 144.775 96.229  105.659 1.00 111.74 ? 66  LYS H O   1 
ATOM 1297 C CB  . LYS B 2 66  ? 142.088 95.336  105.513 1.00 111.74 ? 66  LYS H CB  1 
ATOM 1298 C CG  . LYS B 2 66  ? 141.729 96.796  105.258 1.00 111.74 ? 66  LYS H CG  1 
ATOM 1299 C CD  . LYS B 2 66  ? 140.453 96.923  104.444 1.00 111.74 ? 66  LYS H CD  1 
ATOM 1300 C CE  . LYS B 2 66  ? 140.240 98.353  103.976 1.00 111.74 ? 66  LYS H CE  1 
ATOM 1301 N NZ  . LYS B 2 66  ? 141.502 98.970  103.486 1.00 111.74 ? 66  LYS H NZ  1 
ATOM 1302 N N   . PHE B 2 67  ? 144.564 96.550  107.876 1.00 113.63 ? 67  PHE H N   1 
ATOM 1303 C CA  . PHE B 2 67  ? 145.755 97.377  108.005 1.00 113.63 ? 67  PHE H CA  1 
ATOM 1304 C C   . PHE B 2 67  ? 146.605 96.968  109.201 1.00 113.63 ? 67  PHE H C   1 
ATOM 1305 O O   . PHE B 2 67  ? 147.531 97.700  109.567 1.00 113.63 ? 67  PHE H O   1 
ATOM 1306 C CB  . PHE B 2 67  ? 145.379 98.858  108.124 1.00 113.63 ? 67  PHE H CB  1 
ATOM 1307 C CG  . PHE B 2 67  ? 145.445 99.605  106.827 1.00 113.63 ? 67  PHE H CG  1 
ATOM 1308 C CD1 . PHE B 2 67  ? 144.393 99.554  105.930 1.00 113.63 ? 67  PHE H CD1 1 
ATOM 1309 C CD2 . PHE B 2 67  ? 146.563 100.350 106.499 1.00 113.63 ? 67  PHE H CD2 1 
ATOM 1310 C CE1 . PHE B 2 67  ? 144.453 100.240 104.735 1.00 113.63 ? 67  PHE H CE1 1 
ATOM 1311 C CE2 . PHE B 2 67  ? 146.630 101.036 105.304 1.00 113.63 ? 67  PHE H CE2 1 
ATOM 1312 C CZ  . PHE B 2 67  ? 145.573 100.981 104.421 1.00 113.63 ? 67  PHE H CZ  1 
ATOM 1313 N N   . MET B 2 68  ? 146.311 95.821  109.819 1.00 121.05 ? 68  MET H N   1 
ATOM 1314 C CA  . MET B 2 68  ? 147.016 95.419  111.032 1.00 121.05 ? 68  MET H CA  1 
ATOM 1315 C C   . MET B 2 68  ? 148.483 95.110  110.755 1.00 121.05 ? 68  MET H C   1 
ATOM 1316 O O   . MET B 2 68  ? 149.353 95.418  111.578 1.00 121.05 ? 68  MET H O   1 
ATOM 1317 C CB  . MET B 2 68  ? 146.324 94.207  111.654 1.00 121.05 ? 68  MET H CB  1 
ATOM 1318 C CG  . MET B 2 68  ? 146.817 93.850  113.045 1.00 121.05 ? 68  MET H CG  1 
ATOM 1319 S SD  . MET B 2 68  ? 146.649 95.210  114.213 1.00 121.05 ? 68  MET H SD  1 
ATOM 1320 C CE  . MET B 2 68  ? 145.119 94.765  115.028 1.00 121.05 ? 68  MET H CE  1 
ATOM 1321 N N   . GLY B 2 69  ? 148.775 94.497  109.608 1.00 121.26 ? 69  GLY H N   1 
ATOM 1322 C CA  . GLY B 2 69  ? 150.130 94.037  109.351 1.00 121.26 ? 69  GLY H CA  1 
ATOM 1323 C C   . GLY B 2 69  ? 151.139 95.160  109.202 1.00 121.26 ? 69  GLY H C   1 
ATOM 1324 O O   . GLY B 2 69  ? 152.247 95.084  109.741 1.00 121.26 ? 69  GLY H O   1 
ATOM 1325 N N   . LYS B 2 70  ? 150.775 96.218  108.478 1.00 124.64 ? 70  LYS H N   1 
ATOM 1326 C CA  . LYS B 2 70  ? 151.722 97.248  108.068 1.00 124.64 ? 70  LYS H CA  1 
ATOM 1327 C C   . LYS B 2 70  ? 151.530 98.562  108.822 1.00 124.64 ? 70  LYS H C   1 
ATOM 1328 O O   . LYS B 2 70  ? 151.887 99.629  108.318 1.00 124.64 ? 70  LYS H O   1 
ATOM 1329 C CB  . LYS B 2 70  ? 151.623 97.481  106.561 1.00 124.64 ? 70  LYS H CB  1 
ATOM 1330 C CG  . LYS B 2 70  ? 150.300 98.080  106.105 1.00 124.64 ? 70  LYS H CG  1 
ATOM 1331 C CD  . LYS B 2 70  ? 150.129 97.965  104.601 1.00 124.64 ? 70  LYS H CD  1 
ATOM 1332 C CE  . LYS B 2 70  ? 150.074 96.512  104.165 1.00 124.64 ? 70  LYS H CE  1 
ATOM 1333 N NZ  . LYS B 2 70  ? 149.216 95.699  105.071 1.00 124.64 ? 70  LYS H NZ  1 
ATOM 1334 N N   . ALA B 2 71  ? 150.986 98.505  110.034 1.00 118.48 ? 71  ALA H N   1 
ATOM 1335 C CA  . ALA B 2 71  ? 150.770 99.707  110.825 1.00 118.48 ? 71  ALA H CA  1 
ATOM 1336 C C   . ALA B 2 71  ? 151.340 99.513  112.221 1.00 118.48 ? 71  ALA H C   1 
ATOM 1337 O O   . ALA B 2 71  ? 151.263 98.420  112.787 1.00 118.48 ? 71  ALA H O   1 
ATOM 1338 C CB  . ALA B 2 71  ? 149.282 100.063 110.912 1.00 118.48 ? 71  ALA H CB  1 
ATOM 1339 N N   . THR B 2 72  ? 151.916 100.582 112.766 1.00 117.27 ? 72  THR H N   1 
ATOM 1340 C CA  . THR B 2 72  ? 152.446 100.577 114.125 1.00 117.27 ? 72  THR H CA  1 
ATOM 1341 C C   . THR B 2 72  ? 152.401 102.001 114.650 1.00 117.27 ? 72  THR H C   1 
ATOM 1342 O O   . THR B 2 72  ? 153.147 102.858 114.170 1.00 117.27 ? 72  THR H O   1 
ATOM 1343 C CB  . THR B 2 72  ? 153.876 100.036 114.166 1.00 117.27 ? 72  THR H CB  1 
ATOM 1344 O OG1 . THR B 2 72  ? 153.910 98.721  113.598 1.00 117.27 ? 72  THR H OG1 1 
ATOM 1345 C CG2 . THR B 2 72  ? 154.379 99.978  115.598 1.00 117.27 ? 72  THR H CG2 1 
ATOM 1346 N N   . LEU B 2 73  ? 151.540 102.252 115.632 1.00 112.83 ? 73  LEU H N   1 
ATOM 1347 C CA  . LEU B 2 73  ? 151.305 103.595 116.159 1.00 112.83 ? 73  LEU H CA  1 
ATOM 1348 C C   . LEU B 2 73  ? 151.892 103.682 117.564 1.00 112.83 ? 73  LEU H C   1 
ATOM 1349 O O   . LEU B 2 73  ? 151.310 103.166 118.523 1.00 112.83 ? 73  LEU H O   1 
ATOM 1350 C CB  . LEU B 2 73  ? 149.816 103.930 116.160 1.00 112.83 ? 73  LEU H CB  1 
ATOM 1351 C CG  . LEU B 2 73  ? 149.160 104.324 114.834 1.00 112.83 ? 73  LEU H CG  1 
ATOM 1352 C CD1 . LEU B 2 73  ? 149.020 103.139 113.893 1.00 112.83 ? 73  LEU H CD1 1 
ATOM 1353 C CD2 . LEU B 2 73  ? 147.805 104.951 115.102 1.00 112.83 ? 73  LEU H CD2 1 
ATOM 1354 N N   . THR B 2 74  ? 153.042 104.338 117.682 1.00 117.88 ? 74  THR H N   1 
ATOM 1355 C CA  . THR B 2 74  ? 153.700 104.569 118.960 1.00 117.88 ? 74  THR H CA  1 
ATOM 1356 C C   . THR B 2 74  ? 153.794 106.068 119.203 1.00 117.88 ? 74  THR H C   1 
ATOM 1357 O O   . THR B 2 74  ? 154.206 106.819 118.313 1.00 117.88 ? 74  THR H O   1 
ATOM 1358 C CB  . THR B 2 74  ? 155.094 103.940 118.981 1.00 117.88 ? 74  THR H CB  1 
ATOM 1359 O OG1 . THR B 2 74  ? 155.879 104.481 117.911 1.00 117.88 ? 74  THR H OG1 1 
ATOM 1360 C CG2 . THR B 2 74  ? 154.997 102.432 118.816 1.00 117.88 ? 74  THR H CG2 1 
ATOM 1361 N N   . VAL B 2 75  ? 153.418 106.500 120.403 1.00 118.25 ? 75  VAL H N   1 
ATOM 1362 C CA  . VAL B 2 75  ? 153.345 107.916 120.745 1.00 118.25 ? 75  VAL H CA  1 
ATOM 1363 C C   . VAL B 2 75  ? 154.261 108.180 121.931 1.00 118.25 ? 75  VAL H C   1 
ATOM 1364 O O   . VAL B 2 75  ? 154.233 107.440 122.921 1.00 118.25 ? 75  VAL H O   1 
ATOM 1365 C CB  . VAL B 2 75  ? 151.902 108.347 121.063 1.00 118.25 ? 75  VAL H CB  1 
ATOM 1366 C CG1 . VAL B 2 75  ? 151.863 109.802 121.503 1.00 118.25 ? 75  VAL H CG1 1 
ATOM 1367 C CG2 . VAL B 2 75  ? 151.007 108.126 119.857 1.00 118.25 ? 75  VAL H CG2 1 
ATOM 1368 N N   . ASP B 2 76  ? 155.071 109.230 121.827 1.00 121.90 ? 76  ASP H N   1 
ATOM 1369 C CA  . ASP B 2 76  ? 155.944 109.667 122.908 1.00 121.90 ? 76  ASP H CA  1 
ATOM 1370 C C   . ASP B 2 76  ? 155.256 110.840 123.598 1.00 121.90 ? 76  ASP H C   1 
ATOM 1371 O O   . ASP B 2 76  ? 154.992 111.868 122.965 1.00 121.90 ? 76  ASP H O   1 
ATOM 1372 C CB  . ASP B 2 76  ? 157.320 110.059 122.360 1.00 121.90 ? 76  ASP H CB  1 
ATOM 1373 C CG  . ASP B 2 76  ? 158.170 110.861 123.350 1.00 121.90 ? 76  ASP H CG  1 
ATOM 1374 O OD1 . ASP B 2 76  ? 157.780 111.050 124.521 1.00 121.90 ? 76  ASP H OD1 1 
ATOM 1375 O OD2 . ASP B 2 76  ? 159.289 111.253 122.958 1.00 121.90 ? 76  ASP H OD2 1 
ATOM 1376 N N   . ARG B 2 77  ? 154.975 110.686 124.893 1.00 121.08 ? 77  ARG H N   1 
ATOM 1377 C CA  . ARG B 2 77  ? 154.253 111.711 125.638 1.00 121.08 ? 77  ARG H CA  1 
ATOM 1378 C C   . ARG B 2 77  ? 155.153 112.822 126.161 1.00 121.08 ? 77  ARG H C   1 
ATOM 1379 O O   . ARG B 2 77  ? 154.639 113.852 126.610 1.00 121.08 ? 77  ARG H O   1 
ATOM 1380 C CB  . ARG B 2 77  ? 153.503 111.075 126.811 1.00 121.08 ? 77  ARG H CB  1 
ATOM 1381 C CG  . ARG B 2 77  ? 152.370 110.150 126.401 1.00 121.08 ? 77  ARG H CG  1 
ATOM 1382 C CD  . ARG B 2 77  ? 151.065 110.912 126.252 1.00 121.08 ? 77  ARG H CD  1 
ATOM 1383 N NE  . ARG B 2 77  ? 150.517 111.313 127.542 1.00 121.08 ? 77  ARG H NE  1 
ATOM 1384 C CZ  . ARG B 2 77  ? 149.676 110.580 128.258 1.00 121.08 ? 77  ARG H CZ  1 
ATOM 1385 N NH1 . ARG B 2 77  ? 149.265 109.394 127.841 1.00 121.08 ? 77  ARG H NH1 1 
ATOM 1386 N NH2 . ARG B 2 77  ? 149.235 111.050 129.421 1.00 121.08 ? 77  ARG H NH2 1 
ATOM 1387 N N   . SER B 2 78  ? 156.475 112.640 126.127 1.00 124.45 ? 78  SER H N   1 
ATOM 1388 C CA  . SER B 2 78  ? 157.374 113.655 126.668 1.00 124.45 ? 78  SER H CA  1 
ATOM 1389 C C   . SER B 2 78  ? 157.330 114.933 125.839 1.00 124.45 ? 78  SER H C   1 
ATOM 1390 O O   . SER B 2 78  ? 157.152 116.031 126.381 1.00 124.45 ? 78  SER H O   1 
ATOM 1391 C CB  . SER B 2 78  ? 158.800 113.110 126.740 1.00 124.45 ? 78  SER H CB  1 
ATOM 1392 O OG  . SER B 2 78  ? 159.379 113.033 125.449 1.00 124.45 ? 78  SER H OG  1 
ATOM 1393 N N   . SER B 2 79  ? 157.488 114.812 124.523 1.00 124.82 ? 79  SER H N   1 
ATOM 1394 C CA  . SER B 2 79  ? 157.455 115.955 123.623 1.00 124.82 ? 79  SER H CA  1 
ATOM 1395 C C   . SER B 2 79  ? 156.118 116.110 122.913 1.00 124.82 ? 79  SER H C   1 
ATOM 1396 O O   . SER B 2 79  ? 155.994 116.977 122.042 1.00 124.82 ? 79  SER H O   1 
ATOM 1397 C CB  . SER B 2 79  ? 158.579 115.846 122.589 1.00 124.82 ? 79  SER H CB  1 
ATOM 1398 O OG  . SER B 2 79  ? 158.353 114.763 121.706 1.00 124.82 ? 79  SER H OG  1 
ATOM 1399 N N   . SER B 2 80  ? 155.125 115.289 123.261 1.00 121.84 ? 80  SER H N   1 
ATOM 1400 C CA  . SER B 2 80  ? 153.781 115.368 122.687 1.00 121.84 ? 80  SER H CA  1 
ATOM 1401 C C   . SER B 2 80  ? 153.815 115.206 121.167 1.00 121.84 ? 80  SER H C   1 
ATOM 1402 O O   . SER B 2 80  ? 153.266 116.017 120.420 1.00 121.84 ? 80  SER H O   1 
ATOM 1403 C CB  . SER B 2 80  ? 153.089 116.674 123.086 1.00 121.84 ? 80  SER H CB  1 
ATOM 1404 O OG  . SER B 2 80  ? 153.465 117.733 122.223 1.00 121.84 ? 80  SER H OG  1 
ATOM 1405 N N   . THR B 2 81  ? 154.469 114.141 120.711 1.00 122.65 ? 81  THR H N   1 
ATOM 1406 C CA  . THR B 2 81  ? 154.542 113.826 119.293 1.00 122.65 ? 81  THR H CA  1 
ATOM 1407 C C   . THR B 2 81  ? 154.079 112.395 119.062 1.00 122.65 ? 81  THR H C   1 
ATOM 1408 O O   . THR B 2 81  ? 154.235 111.525 119.924 1.00 122.65 ? 81  THR H O   1 
ATOM 1409 C CB  . THR B 2 81  ? 155.964 114.015 118.737 1.00 122.65 ? 81  THR H CB  1 
ATOM 1410 O OG1 . THR B 2 81  ? 155.950 113.839 117.316 1.00 122.65 ? 81  THR H OG1 1 
ATOM 1411 C CG2 . THR B 2 81  ? 156.927 113.016 119.357 1.00 122.65 ? 81  THR H CG2 1 
ATOM 1412 N N   . ALA B 2 82  ? 153.489 112.164 117.893 1.00 117.60 ? 82  ALA H N   1 
ATOM 1413 C CA  . ALA B 2 82  ? 152.997 110.850 117.507 1.00 117.60 ? 82  ALA H CA  1 
ATOM 1414 C C   . ALA B 2 82  ? 153.579 110.482 116.153 1.00 117.60 ? 82  ALA H C   1 
ATOM 1415 O O   . ALA B 2 82  ? 153.521 111.280 115.212 1.00 117.60 ? 82  ALA H O   1 
ATOM 1416 C CB  . ALA B 2 82  ? 151.468 110.823 117.453 1.00 117.60 ? 82  ALA H CB  1 
ATOM 1417 N N   . TYR B 2 83  ? 154.135 109.278 116.056 1.00 119.83 ? 83  TYR H N   1 
ATOM 1418 C CA  . TYR B 2 83  ? 154.775 108.820 114.834 1.00 119.83 ? 83  TYR H CA  1 
ATOM 1419 C C   . TYR B 2 83  ? 154.443 107.354 114.599 1.00 119.83 ? 83  TYR H C   1 
ATOM 1420 O O   . TYR B 2 83  ? 154.204 106.598 115.543 1.00 119.83 ? 83  TYR H O   1 
ATOM 1421 C CB  . TYR B 2 83  ? 156.295 109.038 114.892 1.00 119.83 ? 83  TYR H CB  1 
ATOM 1422 C CG  . TYR B 2 83  ? 157.005 108.252 115.971 1.00 119.83 ? 83  TYR H CG  1 
ATOM 1423 C CD1 . TYR B 2 83  ? 157.175 108.783 117.243 1.00 119.83 ? 83  TYR H CD1 1 
ATOM 1424 C CD2 . TYR B 2 83  ? 157.517 106.987 115.717 1.00 119.83 ? 83  TYR H CD2 1 
ATOM 1425 C CE1 . TYR B 2 83  ? 157.825 108.074 118.232 1.00 119.83 ? 83  TYR H CE1 1 
ATOM 1426 C CE2 . TYR B 2 83  ? 158.168 106.270 116.700 1.00 119.83 ? 83  TYR H CE2 1 
ATOM 1427 C CZ  . TYR B 2 83  ? 158.319 106.818 117.955 1.00 119.83 ? 83  TYR H CZ  1 
ATOM 1428 O OH  . TYR B 2 83  ? 158.968 106.106 118.937 1.00 119.83 ? 83  TYR H OH  1 
ATOM 1429 N N   . MET B 2 84  ? 154.433 106.958 113.328 1.00 120.16 ? 84  MET H N   1 
ATOM 1430 C CA  . MET B 2 84  ? 154.105 105.594 112.945 1.00 120.16 ? 84  MET H CA  1 
ATOM 1431 C C   . MET B 2 84  ? 155.113 105.078 111.929 1.00 120.16 ? 84  MET H C   1 
ATOM 1432 O O   . MET B 2 84  ? 155.789 105.848 111.243 1.00 120.16 ? 84  MET H O   1 
ATOM 1433 C CB  . MET B 2 84  ? 152.697 105.480 112.349 1.00 120.16 ? 84  MET H CB  1 
ATOM 1434 C CG  . MET B 2 84  ? 152.498 106.287 111.082 1.00 120.16 ? 84  MET H CG  1 
ATOM 1435 S SD  . MET B 2 84  ? 150.759 106.480 110.661 1.00 120.16 ? 84  MET H SD  1 
ATOM 1436 C CE  . MET B 2 84  ? 150.861 106.659 108.883 1.00 120.16 ? 84  MET H CE  1 
ATOM 1437 N N   . ASP B 2 85  ? 155.196 103.752 111.839 1.00 128.10 ? 85  ASP H N   1 
ATOM 1438 C CA  . ASP B 2 85  ? 156.046 103.073 110.873 1.00 128.10 ? 85  ASP H CA  1 
ATOM 1439 C C   . ASP B 2 85  ? 155.208 102.104 110.052 1.00 128.10 ? 85  ASP H C   1 
ATOM 1440 O O   . ASP B 2 85  ? 154.208 101.564 110.530 1.00 128.10 ? 85  ASP H O   1 
ATOM 1441 C CB  . ASP B 2 85  ? 157.186 102.305 111.558 1.00 128.10 ? 85  ASP H CB  1 
ATOM 1442 C CG  . ASP B 2 85  ? 158.097 103.206 112.369 1.00 128.10 ? 85  ASP H CG  1 
ATOM 1443 O OD1 . ASP B 2 85  ? 158.027 104.440 112.200 1.00 128.10 ? 85  ASP H OD1 1 
ATOM 1444 O OD2 . ASP B 2 85  ? 158.885 102.677 113.180 1.00 128.10 ? 85  ASP H OD2 1 
ATOM 1445 N N   . LEU B 2 86  ? 155.624 101.893 108.805 1.00 131.61 ? 86  LEU H N   1 
ATOM 1446 C CA  . LEU B 2 86  ? 155.015 100.901 107.927 1.00 131.61 ? 86  LEU H CA  1 
ATOM 1447 C C   . LEU B 2 86  ? 156.073 99.866  107.577 1.00 131.61 ? 86  LEU H C   1 
ATOM 1448 O O   . LEU B 2 86  ? 157.109 100.204 106.995 1.00 131.61 ? 86  LEU H O   1 
ATOM 1449 C CB  . LEU B 2 86  ? 154.441 101.545 106.662 1.00 131.61 ? 86  LEU H CB  1 
ATOM 1450 C CG  . LEU B 2 86  ? 153.100 102.279 106.785 1.00 131.61 ? 86  LEU H CG  1 
ATOM 1451 C CD1 . LEU B 2 86  ? 153.237 103.589 107.549 1.00 131.61 ? 86  LEU H CD1 1 
ATOM 1452 C CD2 . LEU B 2 86  ? 152.485 102.517 105.415 1.00 131.61 ? 86  LEU H CD2 1 
ATOM 1453 N N   . HIS B 2 87  ? 155.810 98.608  107.933 1.00 135.70 ? 87  HIS H N   1 
ATOM 1454 C CA  . HIS B 2 87  ? 156.839 97.577  107.832 1.00 135.70 ? 87  HIS H CA  1 
ATOM 1455 C C   . HIS B 2 87  ? 157.133 97.216  106.381 1.00 135.70 ? 87  HIS H C   1 
ATOM 1456 O O   . HIS B 2 87  ? 158.299 97.142  105.975 1.00 135.70 ? 87  HIS H O   1 
ATOM 1457 C CB  . HIS B 2 87  ? 156.412 96.342  108.624 1.00 135.70 ? 87  HIS H CB  1 
ATOM 1458 C CG  . HIS B 2 87  ? 156.519 96.513  110.106 1.00 135.70 ? 87  HIS H CG  1 
ATOM 1459 N ND1 . HIS B 2 87  ? 157.157 97.589  110.685 1.00 135.70 ? 87  HIS H ND1 1 
ATOM 1460 C CD2 . HIS B 2 87  ? 156.069 95.748  111.128 1.00 135.70 ? 87  HIS H CD2 1 
ATOM 1461 C CE1 . HIS B 2 87  ? 157.096 97.478  112.000 1.00 135.70 ? 87  HIS H CE1 1 
ATOM 1462 N NE2 . HIS B 2 87  ? 156.441 96.370  112.295 1.00 135.70 ? 87  HIS H NE2 1 
ATOM 1463 N N   . ASN B 2 88  ? 156.093 96.988  105.582 1.00 138.52 ? 88  ASN H N   1 
ATOM 1464 C CA  . ASN B 2 88  ? 156.250 96.562  104.194 1.00 138.52 ? 88  ASN H CA  1 
ATOM 1465 C C   . ASN B 2 88  ? 155.624 97.610  103.285 1.00 138.52 ? 88  ASN H C   1 
ATOM 1466 O O   . ASN B 2 88  ? 154.472 98.004  103.487 1.00 138.52 ? 88  ASN H O   1 
ATOM 1467 C CB  . ASN B 2 88  ? 155.618 95.190  103.964 1.00 138.52 ? 88  ASN H CB  1 
ATOM 1468 C CG  . ASN B 2 88  ? 156.627 94.065  104.054 1.00 138.52 ? 88  ASN H CG  1 
ATOM 1469 O OD1 . ASN B 2 88  ? 157.822 94.302  104.231 1.00 138.52 ? 88  ASN H OD1 1 
ATOM 1470 N ND2 . ASN B 2 88  ? 156.152 92.832  103.931 1.00 138.52 ? 88  ASN H ND2 1 
ATOM 1471 N N   . LEU B 2 89  ? 156.382 98.057  102.290 1.00 137.39 ? 89  LEU H N   1 
ATOM 1472 C CA  . LEU B 2 89  ? 155.943 99.088  101.355 1.00 137.39 ? 89  LEU H CA  1 
ATOM 1473 C C   . LEU B 2 89  ? 156.098 98.551  99.936  1.00 137.39 ? 89  LEU H C   1 
ATOM 1474 O O   . LEU B 2 89  ? 157.176 98.640  99.344  1.00 137.39 ? 89  LEU H O   1 
ATOM 1475 C CB  . LEU B 2 89  ? 156.745 100.369 101.551 1.00 137.39 ? 89  LEU H CB  1 
ATOM 1476 C CG  . LEU B 2 89  ? 156.541 101.074 102.890 1.00 137.39 ? 89  LEU H CG  1 
ATOM 1477 C CD1 . LEU B 2 89  ? 157.494 102.249 103.016 1.00 137.39 ? 89  LEU H CD1 1 
ATOM 1478 C CD2 . LEU B 2 89  ? 155.101 101.525 103.031 1.00 137.39 ? 89  LEU H CD2 1 
ATOM 1479 N N   . THR B 2 90  ? 155.015 98.002  99.389  1.00 137.47 ? 90  THR H N   1 
ATOM 1480 C CA  . THR B 2 90  ? 155.012 97.488  98.026  1.00 137.47 ? 90  THR H CA  1 
ATOM 1481 C C   . THR B 2 90  ? 154.116 98.313  97.111  1.00 137.47 ? 90  THR H C   1 
ATOM 1482 O O   . THR B 2 90  ? 154.580 98.837  96.094  1.00 137.47 ? 90  THR H O   1 
ATOM 1483 C CB  . THR B 2 90  ? 154.572 96.017  98.023  1.00 137.47 ? 90  THR H CB  1 
ATOM 1484 O OG1 . THR B 2 90  ? 153.305 95.896  98.680  1.00 137.47 ? 90  THR H OG1 1 
ATOM 1485 C CG2 . THR B 2 90  ? 155.596 95.154  98.745  1.00 137.47 ? 90  THR H CG2 1 
ATOM 1486 N N   . SER B 2 91  ? 152.837 98.449  97.453  1.00 135.15 ? 91  SER H N   1 
ATOM 1487 C CA  . SER B 2 91  ? 151.937 99.313  96.705  1.00 135.15 ? 91  SER H CA  1 
ATOM 1488 C C   . SER B 2 91  ? 150.998 100.110 97.597  1.00 135.15 ? 91  SER H C   1 
ATOM 1489 O O   . SER B 2 91  ? 150.226 100.921 97.077  1.00 135.15 ? 91  SER H O   1 
ATOM 1490 C CB  . SER B 2 91  ? 151.114 98.493  95.700  1.00 135.15 ? 91  SER H CB  1 
ATOM 1491 O OG  . SER B 2 91  ? 151.856 98.249  94.518  1.00 135.15 ? 91  SER H OG  1 
ATOM 1492 N N   . ALA B 2 92  ? 151.036 99.907  98.916  1.00 132.95 ? 92  ALA H N   1 
ATOM 1493 C CA  . ALA B 2 92  ? 150.206 100.702 99.813  1.00 132.95 ? 92  ALA H CA  1 
ATOM 1494 C C   . ALA B 2 92  ? 150.679 102.149 99.858  1.00 132.95 ? 92  ALA H C   1 
ATOM 1495 O O   . ALA B 2 92  ? 149.864 103.071 99.984  1.00 132.95 ? 92  ALA H O   1 
ATOM 1496 C CB  . ALA B 2 92  ? 150.210 100.090 101.213 1.00 132.95 ? 92  ALA H CB  1 
ATOM 1497 N N   . ASP B 2 93  ? 151.986 102.368 99.752  1.00 134.69 ? 93  ASP H N   1 
ATOM 1498 C CA  . ASP B 2 93  ? 152.543 103.717 99.757  1.00 134.69 ? 93  ASP H CA  1 
ATOM 1499 C C   . ASP B 2 93  ? 152.192 104.390 98.438  1.00 134.69 ? 93  ASP H C   1 
ATOM 1500 O O   . ASP B 2 93  ? 152.908 104.259 97.444  1.00 134.69 ? 93  ASP H O   1 
ATOM 1501 C CB  . ASP B 2 93  ? 154.051 103.668 99.976  1.00 134.69 ? 93  ASP H CB  1 
ATOM 1502 C CG  . ASP B 2 93  ? 154.741 102.653 99.082  1.00 134.69 ? 93  ASP H CG  1 
ATOM 1503 O OD1 . ASP B 2 93  ? 154.037 101.848 98.438  1.00 134.69 ? 93  ASP H OD1 1 
ATOM 1504 O OD2 . ASP B 2 93  ? 155.988 102.665 99.018  1.00 134.69 ? 93  ASP H OD2 1 
ATOM 1505 N N   . SER B 2 94  ? 151.080 105.118 98.423  1.00 128.79 ? 94  SER H N   1 
ATOM 1506 C CA  . SER B 2 94  ? 150.602 105.756 97.204  1.00 128.79 ? 94  SER H CA  1 
ATOM 1507 C C   . SER B 2 94  ? 150.612 107.272 97.288  1.00 128.79 ? 94  SER H C   1 
ATOM 1508 O O   . SER B 2 94  ? 151.226 107.930 96.439  1.00 128.79 ? 94  SER H O   1 
ATOM 1509 C CB  . SER B 2 94  ? 149.186 105.257 96.877  1.00 128.79 ? 94  SER H CB  1 
ATOM 1510 O OG  . SER B 2 94  ? 149.201 103.885 96.523  1.00 128.79 ? 94  SER H OG  1 
ATOM 1511 N N   . ALA B 2 95  ? 149.956 107.850 98.287  1.00 120.59 ? 95  ALA H N   1 
ATOM 1512 C CA  . ALA B 2 95  ? 149.795 109.297 98.354  1.00 120.59 ? 95  ALA H CA  1 
ATOM 1513 C C   . ALA B 2 95  ? 149.698 109.708 99.821  1.00 120.59 ? 95  ALA H C   1 
ATOM 1514 O O   . ALA B 2 95  ? 150.142 108.977 100.711 1.00 120.59 ? 95  ALA H O   1 
ATOM 1515 C CB  . ALA B 2 95  ? 148.590 109.742 97.511  1.00 120.59 ? 95  ALA H CB  1 
ATOM 1516 N N   . VAL B 2 96  ? 149.137 110.895 100.064 1.00 114.93 ? 96  VAL H N   1 
ATOM 1517 C CA  . VAL B 2 96  ? 149.235 111.539 101.367 1.00 114.93 ? 96  VAL H CA  1 
ATOM 1518 C C   . VAL B 2 96  ? 148.637 110.692 102.489 1.00 114.93 ? 96  VAL H C   1 
ATOM 1519 O O   . VAL B 2 96  ? 147.644 109.976 102.307 1.00 114.93 ? 96  VAL H O   1 
ATOM 1520 C CB  . VAL B 2 96  ? 148.565 112.922 101.317 1.00 114.93 ? 96  VAL H CB  1 
ATOM 1521 C CG1 . VAL B 2 96  ? 149.277 113.815 100.317 1.00 114.93 ? 96  VAL H CG1 1 
ATOM 1522 C CG2 . VAL B 2 96  ? 147.103 112.786 100.944 1.00 114.93 ? 96  VAL H CG2 1 
ATOM 1523 N N   . TYR B 2 97  ? 149.266 110.772 103.663 1.00 110.00 ? 97  TYR H N   1 
ATOM 1524 C CA  . TYR B 2 97  ? 148.779 110.164 104.902 1.00 110.00 ? 97  TYR H CA  1 
ATOM 1525 C C   . TYR B 2 97  ? 148.507 111.300 105.884 1.00 110.00 ? 97  TYR H C   1 
ATOM 1526 O O   . TYR B 2 97  ? 149.440 111.840 106.486 1.00 110.00 ? 97  TYR H O   1 
ATOM 1527 C CB  . TYR B 2 97  ? 149.789 109.180 105.496 1.00 110.00 ? 97  TYR H CB  1 
ATOM 1528 C CG  . TYR B 2 97  ? 150.066 107.919 104.702 1.00 110.00 ? 97  TYR H CG  1 
ATOM 1529 C CD1 . TYR B 2 97  ? 149.604 107.762 103.407 1.00 110.00 ? 97  TYR H CD1 1 
ATOM 1530 C CD2 . TYR B 2 97  ? 150.799 106.881 105.260 1.00 110.00 ? 97  TYR H CD2 1 
ATOM 1531 C CE1 . TYR B 2 97  ? 149.867 106.614 102.687 1.00 110.00 ? 97  TYR H CE1 1 
ATOM 1532 C CE2 . TYR B 2 97  ? 151.063 105.728 104.551 1.00 110.00 ? 97  TYR H CE2 1 
ATOM 1533 C CZ  . TYR B 2 97  ? 150.593 105.600 103.265 1.00 110.00 ? 97  TYR H CZ  1 
ATOM 1534 O OH  . TYR B 2 97  ? 150.851 104.454 102.551 1.00 110.00 ? 97  TYR H OH  1 
ATOM 1535 N N   . PHE B 2 98  ? 147.239 111.661 106.057 1.00 101.30 ? 98  PHE H N   1 
ATOM 1536 C CA  . PHE B 2 98  ? 146.898 112.770 106.937 1.00 101.30 ? 98  PHE H CA  1 
ATOM 1537 C C   . PHE B 2 98  ? 147.062 112.381 108.401 1.00 101.30 ? 98  PHE H C   1 
ATOM 1538 O O   . PHE B 2 98  ? 147.045 111.203 108.763 1.00 101.30 ? 98  PHE H O   1 
ATOM 1539 C CB  . PHE B 2 98  ? 145.466 113.235 106.687 1.00 101.30 ? 98  PHE H CB  1 
ATOM 1540 C CG  . PHE B 2 98  ? 145.305 114.051 105.443 1.00 101.30 ? 98  PHE H CG  1 
ATOM 1541 C CD1 . PHE B 2 98  ? 145.593 115.401 105.445 1.00 101.30 ? 98  PHE H CD1 1 
ATOM 1542 C CD2 . PHE B 2 98  ? 144.860 113.468 104.273 1.00 101.30 ? 98  PHE H CD2 1 
ATOM 1543 C CE1 . PHE B 2 98  ? 145.446 116.153 104.301 1.00 101.30 ? 98  PHE H CE1 1 
ATOM 1544 C CE2 . PHE B 2 98  ? 144.708 114.216 103.127 1.00 101.30 ? 98  PHE H CE2 1 
ATOM 1545 C CZ  . PHE B 2 98  ? 145.002 115.561 103.141 1.00 101.30 ? 98  PHE H CZ  1 
ATOM 1546 N N   . CYS B 2 99  ? 147.227 113.395 109.247 1.00 97.35  ? 99  CYS H N   1 
ATOM 1547 C CA  . CYS B 2 99  ? 147.312 113.222 110.691 1.00 97.35  ? 99  CYS H CA  1 
ATOM 1548 C C   . CYS B 2 99  ? 146.184 114.018 111.326 1.00 97.35  ? 99  CYS H C   1 
ATOM 1549 O O   . CYS B 2 99  ? 146.013 115.203 111.025 1.00 97.35  ? 99  CYS H O   1 
ATOM 1550 C CB  . CYS B 2 99  ? 148.670 113.680 111.221 1.00 97.35  ? 99  CYS H CB  1 
ATOM 1551 S SG  . CYS B 2 99  ? 148.792 113.744 113.018 1.00 97.35  ? 99  CYS H SG  1 
ATOM 1552 N N   . SER B 2 100 ? 145.421 113.373 112.203 1.00 92.62  ? 100 SER H N   1 
ATOM 1553 C CA  . SER B 2 100 ? 144.162 113.919 112.683 1.00 92.62  ? 100 SER H CA  1 
ATOM 1554 C C   . SER B 2 100 ? 144.133 113.953 114.203 1.00 92.62  ? 100 SER H C   1 
ATOM 1555 O O   . SER B 2 100 ? 144.850 113.211 114.878 1.00 92.62  ? 100 SER H O   1 
ATOM 1556 C CB  . SER B 2 100 ? 142.978 113.097 112.173 1.00 92.62  ? 100 SER H CB  1 
ATOM 1557 O OG  . SER B 2 100 ? 142.904 113.146 110.762 1.00 92.62  ? 100 SER H OG  1 
ATOM 1558 N N   . THR B 2 101 ? 143.281 114.826 114.734 1.00 87.42  ? 101 THR H N   1 
ATOM 1559 C CA  . THR B 2 101 ? 143.054 114.915 116.167 1.00 87.42  ? 101 THR H CA  1 
ATOM 1560 C C   . THR B 2 101 ? 141.589 115.231 116.423 1.00 87.42  ? 101 THR H C   1 
ATOM 1561 O O   . THR B 2 101 ? 140.886 115.762 115.560 1.00 87.42  ? 101 THR H O   1 
ATOM 1562 C CB  . THR B 2 101 ? 143.947 115.975 116.821 1.00 87.42  ? 101 THR H CB  1 
ATOM 1563 O OG1 . THR B 2 101 ? 143.810 115.906 118.246 1.00 87.42  ? 101 THR H OG1 1 
ATOM 1564 C CG2 . THR B 2 101 ? 143.563 117.363 116.344 1.00 87.42  ? 101 THR H CG2 1 
ATOM 1565 N N   . GLY B 2 102 ? 141.134 114.893 117.622 1.00 86.57  ? 102 GLY H N   1 
ATOM 1566 C CA  . GLY B 2 102 ? 139.750 115.133 117.981 1.00 86.57  ? 102 GLY H CA  1 
ATOM 1567 C C   . GLY B 2 102 ? 139.482 114.675 119.396 1.00 86.57  ? 102 GLY H C   1 
ATOM 1568 O O   . GLY B 2 102 ? 140.395 114.278 120.123 1.00 86.57  ? 102 GLY H O   1 
ATOM 1569 N N   . TRP B 2 103 ? 138.210 114.732 119.780 1.00 82.26  ? 103 TRP H N   1 
ATOM 1570 C CA  . TRP B 2 103 ? 137.816 114.315 121.116 1.00 82.26  ? 103 TRP H CA  1 
ATOM 1571 C C   . TRP B 2 103 ? 137.794 112.790 121.204 1.00 82.26  ? 103 TRP H C   1 
ATOM 1572 O O   . TRP B 2 103 ? 138.186 112.079 120.275 1.00 82.26  ? 103 TRP H O   1 
ATOM 1573 C CB  . TRP B 2 103 ? 136.463 114.914 121.479 1.00 82.26  ? 103 TRP H CB  1 
ATOM 1574 C CG  . TRP B 2 103 ? 136.558 116.327 121.955 1.00 82.26  ? 103 TRP H CG  1 
ATOM 1575 C CD1 . TRP B 2 103 ? 136.180 117.445 121.276 1.00 82.26  ? 103 TRP H CD1 1 
ATOM 1576 C CD2 . TRP B 2 103 ? 137.070 116.777 123.213 1.00 82.26  ? 103 TRP H CD2 1 
ATOM 1577 N NE1 . TRP B 2 103 ? 136.421 118.564 122.032 1.00 82.26  ? 103 TRP H NE1 1 
ATOM 1578 C CE2 . TRP B 2 103 ? 136.968 118.180 123.227 1.00 82.26  ? 103 TRP H CE2 1 
ATOM 1579 C CE3 . TRP B 2 103 ? 137.603 116.130 124.330 1.00 82.26  ? 103 TRP H CE3 1 
ATOM 1580 C CZ2 . TRP B 2 103 ? 137.379 118.946 124.312 1.00 82.26  ? 103 TRP H CZ2 1 
ATOM 1581 C CZ3 . TRP B 2 103 ? 138.011 116.893 125.406 1.00 82.26  ? 103 TRP H CZ3 1 
ATOM 1582 C CH2 . TRP B 2 103 ? 137.897 118.285 125.390 1.00 82.26  ? 103 TRP H CH2 1 
ATOM 1583 N N   . ASP B 2 104 ? 137.333 112.279 122.349 1.00 88.39  ? 104 ASP H N   1 
ATOM 1584 C CA  . ASP B 2 104 ? 137.398 110.840 122.590 1.00 88.39  ? 104 ASP H CA  1 
ATOM 1585 C C   . ASP B 2 104 ? 136.549 110.066 121.590 1.00 88.39  ? 104 ASP H C   1 
ATOM 1586 O O   . ASP B 2 104 ? 137.002 109.064 121.026 1.00 88.39  ? 104 ASP H O   1 
ATOM 1587 C CB  . ASP B 2 104 ? 136.964 110.524 124.018 1.00 88.39  ? 104 ASP H CB  1 
ATOM 1588 C CG  . ASP B 2 104 ? 137.813 109.443 124.655 1.00 88.39  ? 104 ASP H CG  1 
ATOM 1589 O OD1 . ASP B 2 104 ? 138.593 108.794 123.928 1.00 88.39  ? 104 ASP H OD1 1 
ATOM 1590 O OD2 . ASP B 2 104 ? 137.702 109.241 125.883 1.00 88.39  ? 104 ASP H OD2 1 
ATOM 1591 N N   . TYR B 2 105 ? 135.316 110.512 121.358 1.00 82.74  ? 105 TYR H N   1 
ATOM 1592 C CA  . TYR B 2 105 ? 134.463 109.919 120.339 1.00 82.74  ? 105 TYR H CA  1 
ATOM 1593 C C   . TYR B 2 105 ? 133.884 110.972 119.406 1.00 82.74  ? 105 TYR H C   1 
ATOM 1594 O O   . TYR B 2 105 ? 133.012 110.649 118.593 1.00 82.74  ? 105 TYR H O   1 
ATOM 1595 C CB  . TYR B 2 105 ? 133.320 109.121 120.972 1.00 82.74  ? 105 TYR H CB  1 
ATOM 1596 C CG  . TYR B 2 105 ? 133.737 107.889 121.736 1.00 82.74  ? 105 TYR H CG  1 
ATOM 1597 C CD1 . TYR B 2 105 ? 134.592 106.953 121.176 1.00 82.74  ? 105 TYR H CD1 1 
ATOM 1598 C CD2 . TYR B 2 105 ? 133.263 107.658 123.019 1.00 82.74  ? 105 TYR H CD2 1 
ATOM 1599 C CE1 . TYR B 2 105 ? 134.968 105.824 121.875 1.00 82.74  ? 105 TYR H CE1 1 
ATOM 1600 C CE2 . TYR B 2 105 ? 133.632 106.535 123.724 1.00 82.74  ? 105 TYR H CE2 1 
ATOM 1601 C CZ  . TYR B 2 105 ? 134.485 105.621 123.149 1.00 82.74  ? 105 TYR H CZ  1 
ATOM 1602 O OH  . TYR B 2 105 ? 134.855 104.500 123.853 1.00 82.74  ? 105 TYR H OH  1 
ATOM 1603 N N   . GLY B 2 106 ? 134.336 112.218 119.508 1.00 79.39  ? 106 GLY H N   1 
ATOM 1604 C CA  . GLY B 2 106 ? 133.807 113.280 118.691 1.00 79.39  ? 106 GLY H CA  1 
ATOM 1605 C C   . GLY B 2 106 ? 134.406 113.284 117.306 1.00 79.39  ? 106 GLY H C   1 
ATOM 1606 O O   . GLY B 2 106 ? 135.230 112.438 116.939 1.00 79.39  ? 106 GLY H O   1 
ATOM 1607 N N   . PRO B 2 107 ? 133.989 114.258 116.509 1.00 78.55  ? 107 PRO H N   1 
ATOM 1608 C CA  . PRO B 2 107 ? 134.458 114.324 115.121 1.00 78.55  ? 107 PRO H CA  1 
ATOM 1609 C C   . PRO B 2 107 ? 135.909 114.760 115.029 1.00 78.55  ? 107 PRO H C   1 
ATOM 1610 O O   . PRO B 2 107 ? 136.532 115.077 116.046 1.00 78.55  ? 107 PRO H O   1 
ATOM 1611 C CB  . PRO B 2 107 ? 133.517 115.355 114.493 1.00 78.55  ? 107 PRO H CB  1 
ATOM 1612 C CG  . PRO B 2 107 ? 133.174 116.252 115.624 1.00 78.55  ? 107 PRO H CG  1 
ATOM 1613 C CD  . PRO B 2 107 ? 133.080 115.367 116.835 1.00 78.55  ? 107 PRO H CD  1 
ATOM 1614 N N   . PHE B 2 108 ? 136.458 114.781 113.818 1.00 80.28  ? 108 PHE H N   1 
ATOM 1615 C CA  . PHE B 2 108 ? 137.861 115.123 113.608 1.00 80.28  ? 108 PHE H CA  1 
ATOM 1616 C C   . PHE B 2 108 ? 137.953 116.637 113.464 1.00 80.28  ? 108 PHE H C   1 
ATOM 1617 O O   . PHE B 2 108 ? 137.472 117.203 112.478 1.00 80.28  ? 108 PHE H O   1 
ATOM 1618 C CB  . PHE B 2 108 ? 138.423 114.417 112.376 1.00 80.28  ? 108 PHE H CB  1 
ATOM 1619 C CG  . PHE B 2 108 ? 138.347 112.909 112.431 1.00 80.28  ? 108 PHE H CG  1 
ATOM 1620 C CD1 . PHE B 2 108 ? 137.849 112.248 113.539 1.00 80.28  ? 108 PHE H CD1 1 
ATOM 1621 C CD2 . PHE B 2 108 ? 138.781 112.155 111.359 1.00 80.28  ? 108 PHE H CD2 1 
ATOM 1622 C CE1 . PHE B 2 108 ? 137.778 110.874 113.567 1.00 80.28  ? 108 PHE H CE1 1 
ATOM 1623 C CE2 . PHE B 2 108 ? 138.718 110.782 111.385 1.00 80.28  ? 108 PHE H CE2 1 
ATOM 1624 C CZ  . PHE B 2 108 ? 138.219 110.141 112.490 1.00 80.28  ? 108 PHE H CZ  1 
ATOM 1625 N N   . ASP B 2 109 ? 138.580 117.294 114.439 1.00 84.48  ? 109 ASP H N   1 
ATOM 1626 C CA  . ASP B 2 109 ? 138.510 118.750 114.512 1.00 84.48  ? 109 ASP H CA  1 
ATOM 1627 C C   . ASP B 2 109 ? 139.393 119.409 113.459 1.00 84.48  ? 109 ASP H C   1 
ATOM 1628 O O   . ASP B 2 109 ? 138.899 120.101 112.562 1.00 84.48  ? 109 ASP H O   1 
ATOM 1629 C CB  . ASP B 2 109 ? 138.901 119.220 115.912 1.00 84.48  ? 109 ASP H CB  1 
ATOM 1630 C CG  . ASP B 2 109 ? 137.710 119.342 116.837 1.00 84.48  ? 109 ASP H CG  1 
ATOM 1631 O OD1 . ASP B 2 109 ? 136.721 119.994 116.445 1.00 84.48  ? 109 ASP H OD1 1 
ATOM 1632 O OD2 . ASP B 2 109 ? 137.762 118.786 117.954 1.00 84.48  ? 109 ASP H OD2 1 
ATOM 1633 N N   . SER B 2 110 ? 140.704 119.204 113.550 1.00 91.82  ? 110 SER H N   1 
ATOM 1634 C CA  . SER B 2 110 ? 141.662 119.903 112.704 1.00 91.82  ? 110 SER H CA  1 
ATOM 1635 C C   . SER B 2 110 ? 142.701 118.918 112.195 1.00 91.82  ? 110 SER H C   1 
ATOM 1636 O O   . SER B 2 110 ? 143.180 118.073 112.955 1.00 91.82  ? 110 SER H O   1 
ATOM 1637 C CB  . SER B 2 110 ? 142.345 121.035 113.475 1.00 91.82  ? 110 SER H CB  1 
ATOM 1638 O OG  . SER B 2 110 ? 142.817 120.577 114.729 1.00 91.82  ? 110 SER H OG  1 
ATOM 1639 N N   . TRP B 2 111 ? 143.055 119.033 110.917 1.00 93.37  ? 111 TRP H N   1 
ATOM 1640 C CA  . TRP B 2 111 ? 144.032 118.143 110.307 1.00 93.37  ? 111 TRP H CA  1 
ATOM 1641 C C   . TRP B 2 111 ? 145.228 118.963 109.853 1.00 93.37  ? 111 TRP H C   1 
ATOM 1642 O O   . TRP B 2 111 ? 145.061 119.998 109.200 1.00 93.37  ? 111 TRP H O   1 
ATOM 1643 C CB  . TRP B 2 111 ? 143.449 117.391 109.111 1.00 93.37  ? 111 TRP H CB  1 
ATOM 1644 C CG  . TRP B 2 111 ? 142.399 116.412 109.470 1.00 93.37  ? 111 TRP H CG  1 
ATOM 1645 C CD1 . TRP B 2 111 ? 142.017 116.050 110.721 1.00 93.37  ? 111 TRP H CD1 1 
ATOM 1646 C CD2 . TRP B 2 111 ? 141.673 115.573 108.570 1.00 93.37  ? 111 TRP H CD2 1 
ATOM 1647 N NE1 . TRP B 2 111 ? 141.040 115.090 110.656 1.00 93.37  ? 111 TRP H NE1 1 
ATOM 1648 C CE2 . TRP B 2 111 ? 140.821 114.771 109.344 1.00 93.37  ? 111 TRP H CE2 1 
ATOM 1649 C CE3 . TRP B 2 111 ? 141.646 115.438 107.183 1.00 93.37  ? 111 TRP H CE3 1 
ATOM 1650 C CZ2 . TRP B 2 111 ? 139.951 113.848 108.779 1.00 93.37  ? 111 TRP H CZ2 1 
ATOM 1651 C CZ3 . TRP B 2 111 ? 140.782 114.519 106.625 1.00 93.37  ? 111 TRP H CZ3 1 
ATOM 1652 C CH2 . TRP B 2 111 ? 139.945 113.740 107.420 1.00 93.37  ? 111 TRP H CH2 1 
ATOM 1653 N N   . GLY B 2 112 ? 146.427 118.503 110.192 1.00 102.69 ? 112 GLY H N   1 
ATOM 1654 C CA  . GLY B 2 112 ? 147.620 119.097 109.627 1.00 102.69 ? 112 GLY H CA  1 
ATOM 1655 C C   . GLY B 2 112 ? 147.873 118.600 108.217 1.00 102.69 ? 112 GLY H C   1 
ATOM 1656 O O   . GLY B 2 112 ? 147.277 117.626 107.759 1.00 102.69 ? 112 GLY H O   1 
ATOM 1657 N N   . GLN B 2 113 ? 148.768 119.290 107.515 1.00 116.85 ? 113 GLN H N   1 
ATOM 1658 C CA  . GLN B 2 113 ? 149.143 118.856 106.176 1.00 116.85 ? 113 GLN H CA  1 
ATOM 1659 C C   . GLN B 2 113 ? 149.858 117.513 106.246 1.00 116.85 ? 113 GLN H C   1 
ATOM 1660 O O   . GLN B 2 113 ? 150.573 117.219 107.208 1.00 116.85 ? 113 GLN H O   1 
ATOM 1661 C CB  . GLN B 2 113 ? 150.029 119.904 105.492 1.00 116.85 ? 113 GLN H CB  1 
ATOM 1662 C CG  . GLN B 2 113 ? 151.468 120.001 105.998 1.00 116.85 ? 113 GLN H CG  1 
ATOM 1663 C CD  . GLN B 2 113 ? 151.569 120.281 107.484 1.00 116.85 ? 113 GLN H CD  1 
ATOM 1664 O OE1 . GLN B 2 113 ? 150.702 120.934 108.066 1.00 116.85 ? 113 GLN H OE1 1 
ATOM 1665 N NE2 . GLN B 2 113 ? 152.632 119.788 108.107 1.00 116.85 ? 113 GLN H NE2 1 
ATOM 1666 N N   . GLY B 2 114 ? 149.647 116.686 105.226 1.00 117.71 ? 114 GLY H N   1 
ATOM 1667 C CA  . GLY B 2 114 ? 150.141 115.329 105.230 1.00 117.71 ? 114 GLY H CA  1 
ATOM 1668 C C   . GLY B 2 114 ? 151.396 115.132 104.402 1.00 117.71 ? 114 GLY H C   1 
ATOM 1669 O O   . GLY B 2 114 ? 151.698 115.900 103.493 1.00 117.71 ? 114 GLY H O   1 
ATOM 1670 N N   . THR B 2 115 ? 152.127 114.074 104.739 1.00 122.41 ? 115 THR H N   1 
ATOM 1671 C CA  . THR B 2 115 ? 153.304 113.691 103.975 1.00 122.41 ? 115 THR H CA  1 
ATOM 1672 C C   . THR B 2 115 ? 152.891 113.212 102.592 1.00 122.41 ? 115 THR H C   1 
ATOM 1673 O O   . THR B 2 115 ? 151.760 112.779 102.379 1.00 122.41 ? 115 THR H O   1 
ATOM 1674 C CB  . THR B 2 115 ? 154.066 112.577 104.688 1.00 122.41 ? 115 THR H CB  1 
ATOM 1675 O OG1 . THR B 2 115 ? 153.246 111.404 104.748 1.00 122.41 ? 115 THR H OG1 1 
ATOM 1676 C CG2 . THR B 2 115 ? 154.404 112.997 106.100 1.00 122.41 ? 115 THR H CG2 1 
ATOM 1677 N N   . THR B 2 116 ? 153.817 113.295 101.643 1.00 125.95 ? 116 THR H N   1 
ATOM 1678 C CA  . THR B 2 116 ? 153.590 112.798 100.291 1.00 125.95 ? 116 THR H CA  1 
ATOM 1679 C C   . THR B 2 116 ? 154.546 111.645 100.029 1.00 125.95 ? 116 THR H C   1 
ATOM 1680 O O   . THR B 2 116 ? 155.763 111.799 100.176 1.00 125.95 ? 116 THR H O   1 
ATOM 1681 C CB  . THR B 2 116 ? 153.781 113.903 99.251  1.00 125.95 ? 116 THR H CB  1 
ATOM 1682 O OG1 . THR B 2 116 ? 152.732 114.870 99.382  1.00 125.95 ? 116 THR H OG1 1 
ATOM 1683 C CG2 . THR B 2 116 ? 153.749 113.320 97.848  1.00 125.95 ? 116 THR H CG2 1 
ATOM 1684 N N   . LEU B 2 117 ? 153.997 110.498 99.643  1.00 123.51 ? 117 LEU H N   1 
ATOM 1685 C CA  . LEU B 2 117 ? 154.809 109.320 99.364  1.00 123.51 ? 117 LEU H CA  1 
ATOM 1686 C C   . LEU B 2 117 ? 154.780 108.972 97.880  1.00 123.51 ? 117 LEU H C   1 
ATOM 1687 O O   . LEU B 2 117 ? 154.038 108.087 97.454  1.00 123.51 ? 117 LEU H O   1 
ATOM 1688 C CB  . LEU B 2 117 ? 154.330 108.128 100.194 1.00 123.51 ? 117 LEU H CB  1 
ATOM 1689 C CG  . LEU B 2 117 ? 155.111 107.821 101.473 1.00 123.51 ? 117 LEU H CG  1 
ATOM 1690 C CD1 . LEU B 2 117 ? 155.260 109.064 102.335 1.00 123.51 ? 117 LEU H CD1 1 
ATOM 1691 C CD2 . LEU B 2 117 ? 154.441 106.702 102.253 1.00 123.51 ? 117 LEU H CD2 1 
ATOM 1692 N N   . ALA C 3 2   ? 123.873 138.040 133.813 1.00 93.46  ? 1   ALA C N   1 
ATOM 1693 C CA  . ALA C 3 2   ? 122.960 138.763 132.936 1.00 93.46  ? 1   ALA C CA  1 
ATOM 1694 C C   . ALA C 3 2   ? 121.678 139.128 133.672 1.00 93.46  ? 1   ALA C C   1 
ATOM 1695 O O   . ALA C 3 2   ? 121.276 138.445 134.612 1.00 93.46  ? 1   ALA C O   1 
ATOM 1696 C CB  . ALA C 3 2   ? 122.643 137.938 131.701 1.00 93.46  ? 1   ALA C CB  1 
ATOM 1697 N N   . LYS C 3 3   ? 121.043 140.214 133.241 1.00 94.96  ? 2   LYS C N   1 
ATOM 1698 C CA  . LYS C 3 3   ? 119.791 140.632 133.848 1.00 94.96  ? 2   LYS C CA  1 
ATOM 1699 C C   . LYS C 3 3   ? 118.659 139.702 133.429 1.00 94.96  ? 2   LYS C C   1 
ATOM 1700 O O   . LYS C 3 3   ? 118.713 139.049 132.384 1.00 94.96  ? 2   LYS C O   1 
ATOM 1701 C CB  . LYS C 3 3   ? 119.460 142.072 133.460 1.00 94.96  ? 2   LYS C CB  1 
ATOM 1702 C CG  . LYS C 3 3   ? 119.202 142.277 131.980 1.00 94.96  ? 2   LYS C CG  1 
ATOM 1703 C CD  . LYS C 3 3   ? 118.964 143.744 131.668 1.00 94.96  ? 2   LYS C CD  1 
ATOM 1704 C CE  . LYS C 3 3   ? 117.496 144.104 131.800 1.00 94.96  ? 2   LYS C CE  1 
ATOM 1705 N NZ  . LYS C 3 3   ? 116.755 143.884 130.528 1.00 94.96  ? 2   LYS C NZ  1 
ATOM 1706 N N   . LEU C 3 4   ? 117.629 139.640 134.268 1.00 91.96  ? 3   LEU C N   1 
ATOM 1707 C CA  . LEU C 3 4   ? 116.480 138.798 133.975 1.00 91.96  ? 3   LEU C CA  1 
ATOM 1708 C C   . LEU C 3 4   ? 115.758 139.297 132.731 1.00 91.96  ? 3   LEU C C   1 
ATOM 1709 O O   . LEU C 3 4   ? 115.683 140.502 132.476 1.00 91.96  ? 3   LEU C O   1 
ATOM 1710 C CB  . LEU C 3 4   ? 115.525 138.778 135.165 1.00 91.96  ? 3   LEU C CB  1 
ATOM 1711 C CG  . LEU C 3 4   ? 116.072 138.166 136.452 1.00 91.96  ? 3   LEU C CG  1 
ATOM 1712 C CD1 . LEU C 3 4   ? 115.196 138.548 137.630 1.00 91.96  ? 3   LEU C CD1 1 
ATOM 1713 C CD2 . LEU C 3 4   ? 116.160 136.660 136.316 1.00 91.96  ? 3   LEU C CD2 1 
ATOM 1714 N N   . GLU C 3 5   ? 115.228 138.360 131.953 1.00 88.84  ? 4   GLU C N   1 
ATOM 1715 C CA  . GLU C 3 5   ? 114.493 138.691 130.742 1.00 88.84  ? 4   GLU C CA  1 
ATOM 1716 C C   . GLU C 3 5   ? 113.539 137.546 130.441 1.00 88.84  ? 4   GLU C C   1 
ATOM 1717 O O   . GLU C 3 5   ? 113.636 136.464 131.024 1.00 88.84  ? 4   GLU C O   1 
ATOM 1718 C CB  . GLU C 3 5   ? 115.439 138.953 129.568 1.00 88.84  ? 4   GLU C CB  1 
ATOM 1719 C CG  . GLU C 3 5   ? 116.416 137.826 129.298 1.00 88.84  ? 4   GLU C CG  1 
ATOM 1720 C CD  . GLU C 3 5   ? 117.521 138.232 128.345 1.00 88.84  ? 4   GLU C CD  1 
ATOM 1721 O OE1 . GLU C 3 5   ? 117.538 139.408 127.923 1.00 88.84  ? 4   GLU C OE1 1 
ATOM 1722 O OE2 . GLU C 3 5   ? 118.372 137.378 128.019 1.00 88.84  ? 4   GLU C OE2 1 
ATOM 1723 N N   . THR C 3 6   ? 112.602 137.805 129.532 1.00 83.24  ? 5   THR C N   1 
ATOM 1724 C CA  . THR C 3 6   ? 111.619 136.794 129.172 1.00 83.24  ? 5   THR C CA  1 
ATOM 1725 C C   . THR C 3 6   ? 112.312 135.565 128.601 1.00 83.24  ? 5   THR C C   1 
ATOM 1726 O O   . THR C 3 6   ? 113.179 135.674 127.730 1.00 83.24  ? 5   THR C O   1 
ATOM 1727 C CB  . THR C 3 6   ? 110.625 137.355 128.158 1.00 83.24  ? 5   THR C CB  1 
ATOM 1728 O OG1 . THR C 3 6   ? 111.292 137.578 126.911 1.00 83.24  ? 5   THR C OG1 1 
ATOM 1729 C CG2 . THR C 3 6   ? 110.046 138.668 128.655 1.00 83.24  ? 5   THR C CG2 1 
ATOM 1730 N N   . VAL C 3 7   ? 111.926 134.395 129.097 1.00 78.05  ? 6   VAL C N   1 
ATOM 1731 C CA  . VAL C 3 7   ? 112.515 133.127 128.692 1.00 78.05  ? 6   VAL C CA  1 
ATOM 1732 C C   . VAL C 3 7   ? 111.421 132.282 128.060 1.00 78.05  ? 6   VAL C C   1 
ATOM 1733 O O   . VAL C 3 7   ? 110.376 132.042 128.679 1.00 78.05  ? 6   VAL C O   1 
ATOM 1734 C CB  . VAL C 3 7   ? 113.159 132.392 129.876 1.00 78.05  ? 6   VAL C CB  1 
ATOM 1735 C CG1 . VAL C 3 7   ? 113.697 131.048 129.431 1.00 78.05  ? 6   VAL C CG1 1 
ATOM 1736 C CG2 . VAL C 3 7   ? 114.263 133.237 130.483 1.00 78.05  ? 6   VAL C CG2 1 
ATOM 1737 N N   . THR C 3 8   ? 111.660 131.832 126.834 1.00 78.75  ? 7   THR C N   1 
ATOM 1738 C CA  . THR C 3 8   ? 110.737 130.965 126.118 1.00 78.75  ? 7   THR C CA  1 
ATOM 1739 C C   . THR C 3 8   ? 111.375 129.595 125.931 1.00 78.75  ? 7   THR C C   1 
ATOM 1740 O O   . THR C 3 8   ? 112.567 129.494 125.623 1.00 78.75  ? 7   THR C O   1 
ATOM 1741 C CB  . THR C 3 8   ? 110.342 131.574 124.768 1.00 78.75  ? 7   THR C CB  1 
ATOM 1742 O OG1 . THR C 3 8   ? 109.404 130.715 124.107 1.00 78.75  ? 7   THR C OG1 1 
ATOM 1743 C CG2 . THR C 3 8   ? 111.558 131.793 123.880 1.00 78.75  ? 7   THR C CG2 1 
ATOM 1744 N N   . LEU C 3 9   ? 110.588 128.547 126.152 1.00 78.74  ? 8   LEU C N   1 
ATOM 1745 C CA  . LEU C 3 9   ? 111.036 127.171 126.020 1.00 78.74  ? 8   LEU C CA  1 
ATOM 1746 C C   . LEU C 3 9   ? 110.165 126.470 124.991 1.00 78.74  ? 8   LEU C C   1 
ATOM 1747 O O   . LEU C 3 9   ? 108.934 126.501 125.093 1.00 78.74  ? 8   LEU C O   1 
ATOM 1748 C CB  . LEU C 3 9   ? 110.963 126.439 127.361 1.00 78.74  ? 8   LEU C CB  1 
ATOM 1749 C CG  . LEU C 3 9   ? 111.454 127.220 128.577 1.00 78.74  ? 8   LEU C CG  1 
ATOM 1750 C CD1 . LEU C 3 9   ? 111.268 126.408 129.844 1.00 78.74  ? 8   LEU C CD1 1 
ATOM 1751 C CD2 . LEU C 3 9   ? 112.908 127.602 128.399 1.00 78.74  ? 8   LEU C CD2 1 
ATOM 1752 N N   . GLY C 3 10  ? 110.803 125.843 124.008 1.00 80.71  ? 9   GLY C N   1 
ATOM 1753 C CA  . GLY C 3 10  ? 110.078 125.136 122.973 1.00 80.71  ? 9   GLY C CA  1 
ATOM 1754 C C   . GLY C 3 10  ? 110.283 123.638 123.039 1.00 80.71  ? 9   GLY C C   1 
ATOM 1755 O O   . GLY C 3 10  ? 111.192 123.163 123.726 1.00 80.71  ? 9   GLY C O   1 
ATOM 1756 N N   . ASN C 3 11  ? 109.444 122.889 122.322 1.00 84.55  ? 10  ASN C N   1 
ATOM 1757 C CA  . ASN C 3 11  ? 109.505 121.428 122.307 1.00 84.55  ? 10  ASN C CA  1 
ATOM 1758 C C   . ASN C 3 11  ? 109.420 120.860 123.722 1.00 84.55  ? 10  ASN C C   1 
ATOM 1759 O O   . ASN C 3 11  ? 110.206 119.999 124.121 1.00 84.55  ? 10  ASN C O   1 
ATOM 1760 C CB  . ASN C 3 11  ? 110.764 120.941 121.590 1.00 84.55  ? 10  ASN C CB  1 
ATOM 1761 C CG  . ASN C 3 11  ? 110.760 121.287 120.115 1.00 84.55  ? 10  ASN C CG  1 
ATOM 1762 O OD1 . ASN C 3 11  ? 110.025 122.171 119.676 1.00 84.55  ? 10  ASN C OD1 1 
ATOM 1763 N ND2 . ASN C 3 11  ? 111.583 120.589 119.340 1.00 84.55  ? 10  ASN C ND2 1 
ATOM 1764 N N   . ILE C 3 12  ? 108.454 121.356 124.487 1.00 82.01  ? 11  ILE C N   1 
ATOM 1765 C CA  . ILE C 3 12  ? 108.252 120.966 125.877 1.00 82.01  ? 11  ILE C CA  1 
ATOM 1766 C C   . ILE C 3 12  ? 107.043 120.047 125.954 1.00 82.01  ? 11  ILE C C   1 
ATOM 1767 O O   . ILE C 3 12  ? 106.078 120.208 125.197 1.00 82.01  ? 11  ILE C O   1 
ATOM 1768 C CB  . ILE C 3 12  ? 108.061 122.209 126.767 1.00 82.01  ? 11  ILE C CB  1 
ATOM 1769 C CG1 . ILE C 3 12  ? 109.274 123.123 126.651 1.00 82.01  ? 11  ILE C CG1 1 
ATOM 1770 C CG2 . ILE C 3 12  ? 107.864 121.820 128.217 1.00 82.01  ? 11  ILE C CG2 1 
ATOM 1771 C CD1 . ILE C 3 12  ? 110.540 122.469 127.092 1.00 82.01  ? 11  ILE C CD1 1 
ATOM 1772 N N   . GLY C 3 13  ? 107.093 119.080 126.859 1.00 80.41  ? 12  GLY C N   1 
ATOM 1773 C CA  . GLY C 3 13  ? 105.968 118.211 127.131 1.00 80.41  ? 12  GLY C CA  1 
ATOM 1774 C C   . GLY C 3 13  ? 106.258 116.775 126.751 1.00 80.41  ? 12  GLY C C   1 
ATOM 1775 O O   . GLY C 3 13  ? 107.391 116.394 126.444 1.00 80.41  ? 12  GLY C O   1 
ATOM 1776 N N   . LYS C 3 14  ? 105.199 115.963 126.785 1.00 84.32  ? 13  LYS C N   1 
ATOM 1777 C CA  . LYS C 3 14  ? 105.328 114.551 126.445 1.00 84.32  ? 13  LYS C CA  1 
ATOM 1778 C C   . LYS C 3 14  ? 105.776 114.368 125.001 1.00 84.32  ? 13  LYS C C   1 
ATOM 1779 O O   . LYS C 3 14  ? 106.712 113.611 124.720 1.00 84.32  ? 13  LYS C O   1 
ATOM 1780 C CB  . LYS C 3 14  ? 103.999 113.837 126.690 1.00 84.32  ? 13  LYS C CB  1 
ATOM 1781 C CG  . LYS C 3 14  ? 104.122 112.344 126.935 1.00 84.32  ? 13  LYS C CG  1 
ATOM 1782 C CD  . LYS C 3 14  ? 105.287 112.018 127.848 1.00 84.32  ? 13  LYS C CD  1 
ATOM 1783 C CE  . LYS C 3 14  ? 105.563 110.526 127.865 1.00 84.32  ? 13  LYS C CE  1 
ATOM 1784 N NZ  . LYS C 3 14  ? 104.363 109.752 128.282 1.00 84.32  ? 13  LYS C NZ  1 
ATOM 1785 N N   . ASP C 3 15  ? 105.121 115.058 124.071 1.00 87.80  ? 14  ASP C N   1 
ATOM 1786 C CA  . ASP C 3 15  ? 105.410 114.920 122.650 1.00 87.80  ? 14  ASP C CA  1 
ATOM 1787 C C   . ASP C 3 15  ? 106.262 116.058 122.104 1.00 87.80  ? 14  ASP C C   1 
ATOM 1788 O O   . ASP C 3 15  ? 106.530 116.094 120.899 1.00 87.80  ? 14  ASP C O   1 
ATOM 1789 C CB  . ASP C 3 15  ? 104.105 114.812 121.859 1.00 87.80  ? 14  ASP C CB  1 
ATOM 1790 C CG  . ASP C 3 15  ? 103.196 116.006 122.067 1.00 87.80  ? 14  ASP C CG  1 
ATOM 1791 O OD1 . ASP C 3 15  ? 103.535 116.882 122.890 1.00 87.80  ? 14  ASP C OD1 1 
ATOM 1792 O OD2 . ASP C 3 15  ? 102.138 116.071 121.406 1.00 87.80  ? 14  ASP C OD2 1 
ATOM 1793 N N   . GLY C 3 16  ? 106.701 116.979 122.956 1.00 86.85  ? 15  GLY C N   1 
ATOM 1794 C CA  . GLY C 3 16  ? 107.474 118.115 122.481 1.00 86.85  ? 15  GLY C CA  1 
ATOM 1795 C C   . GLY C 3 16  ? 106.706 119.008 121.532 1.00 86.85  ? 15  GLY C C   1 
ATOM 1796 O O   . GLY C 3 16  ? 107.274 119.505 120.552 1.00 86.85  ? 15  GLY C O   1 
ATOM 1797 N N   . LYS C 3 17  ? 105.417 119.223 121.801 1.00 87.27  ? 16  LYS C N   1 
ATOM 1798 C CA  . LYS C 3 17  ? 104.567 120.052 120.954 1.00 87.27  ? 16  LYS C CA  1 
ATOM 1799 C C   . LYS C 3 17  ? 103.971 121.230 121.715 1.00 87.27  ? 16  LYS C C   1 
ATOM 1800 O O   . LYS C 3 17  ? 102.958 121.790 121.287 1.00 87.27  ? 16  LYS C O   1 
ATOM 1801 C CB  . LYS C 3 17  ? 103.455 119.210 120.328 1.00 87.27  ? 16  LYS C CB  1 
ATOM 1802 C CG  . LYS C 3 17  ? 103.944 118.163 119.343 1.00 87.27  ? 16  LYS C CG  1 
ATOM 1803 C CD  . LYS C 3 17  ? 104.929 118.755 118.347 1.00 87.27  ? 16  LYS C CD  1 
ATOM 1804 C CE  . LYS C 3 17  ? 105.394 117.711 117.345 1.00 87.27  ? 16  LYS C CE  1 
ATOM 1805 N NZ  . LYS C 3 17  ? 106.878 117.631 117.270 1.00 87.27  ? 16  LYS C NZ  1 
ATOM 1806 N N   . GLN C 3 18  ? 104.573 121.618 122.833 1.00 84.35  ? 17  GLN C N   1 
ATOM 1807 C CA  . GLN C 3 18  ? 104.108 122.748 123.621 1.00 84.35  ? 17  GLN C CA  1 
ATOM 1808 C C   . GLN C 3 18  ? 105.223 123.772 123.768 1.00 84.35  ? 17  GLN C C   1 
ATOM 1809 O O   . GLN C 3 18  ? 106.405 123.479 123.574 1.00 84.35  ? 17  GLN C O   1 
ATOM 1810 C CB  . GLN C 3 18  ? 103.620 122.303 125.004 1.00 84.35  ? 17  GLN C CB  1 
ATOM 1811 C CG  . GLN C 3 18  ? 102.896 120.977 125.015 1.00 84.35  ? 17  GLN C CG  1 
ATOM 1812 C CD  . GLN C 3 18  ? 102.359 120.631 126.385 1.00 84.35  ? 17  GLN C CD  1 
ATOM 1813 O OE1 . GLN C 3 18  ? 102.719 119.608 126.964 1.00 84.35  ? 17  GLN C OE1 1 
ATOM 1814 N NE2 . GLN C 3 18  ? 101.491 121.485 126.913 1.00 84.35  ? 17  GLN C NE2 1 
ATOM 1815 N N   . THR C 3 19  ? 104.826 124.991 124.119 1.00 83.49  ? 18  THR C N   1 
ATOM 1816 C CA  . THR C 3 19  ? 105.759 126.085 124.331 1.00 83.49  ? 18  THR C CA  1 
ATOM 1817 C C   . THR C 3 19  ? 105.395 126.790 125.626 1.00 83.49  ? 18  THR C C   1 
ATOM 1818 O O   . THR C 3 19  ? 104.222 127.075 125.878 1.00 83.49  ? 18  THR C O   1 
ATOM 1819 C CB  . THR C 3 19  ? 105.735 127.077 123.161 1.00 83.49  ? 18  THR C CB  1 
ATOM 1820 O OG1 . THR C 3 19  ? 106.096 126.399 121.951 1.00 83.49  ? 18  THR C OG1 1 
ATOM 1821 C CG2 . THR C 3 19  ? 106.708 128.220 123.403 1.00 83.49  ? 18  THR C CG2 1 
ATOM 1822 N N   . LEU C 3 20  ? 106.406 127.068 126.445 1.00 77.87  ? 19  LEU C N   1 
ATOM 1823 C CA  . LEU C 3 20  ? 106.210 127.698 127.746 1.00 77.87  ? 19  LEU C CA  1 
ATOM 1824 C C   . LEU C 3 20  ? 106.989 129.004 127.774 1.00 77.87  ? 19  LEU C C   1 
ATOM 1825 O O   . LEU C 3 20  ? 108.221 128.994 127.720 1.00 77.87  ? 19  LEU C O   1 
ATOM 1826 C CB  . LEU C 3 20  ? 106.658 126.775 128.878 1.00 77.87  ? 19  LEU C CB  1 
ATOM 1827 C CG  . LEU C 3 20  ? 106.657 127.394 130.274 1.00 77.87  ? 19  LEU C CG  1 
ATOM 1828 C CD1 . LEU C 3 20  ? 105.257 127.828 130.657 1.00 77.87  ? 19  LEU C CD1 1 
ATOM 1829 C CD2 . LEU C 3 20  ? 107.210 126.417 131.292 1.00 77.87  ? 19  LEU C CD2 1 
ATOM 1830 N N   . VAL C 3 21  ? 106.278 130.123 127.860 1.00 78.73  ? 20  VAL C N   1 
ATOM 1831 C CA  . VAL C 3 21  ? 106.891 131.442 127.941 1.00 78.73  ? 20  VAL C CA  1 
ATOM 1832 C C   . VAL C 3 21  ? 106.697 131.966 129.356 1.00 78.73  ? 20  VAL C C   1 
ATOM 1833 O O   . VAL C 3 21  ? 105.601 131.869 129.920 1.00 78.73  ? 20  VAL C O   1 
ATOM 1834 C CB  . VAL C 3 21  ? 106.313 132.406 126.889 1.00 78.73  ? 20  VAL C CB  1 
ATOM 1835 C CG1 . VAL C 3 21  ? 104.837 132.683 127.139 1.00 78.73  ? 20  VAL C CG1 1 
ATOM 1836 C CG2 . VAL C 3 21  ? 107.102 133.703 126.876 1.00 78.73  ? 20  VAL C CG2 1 
ATOM 1837 N N   . LEU C 3 22  ? 107.772 132.478 129.945 1.00 78.17  ? 21  LEU C N   1 
ATOM 1838 C CA  . LEU C 3 22  ? 107.748 132.932 131.325 1.00 78.17  ? 21  LEU C CA  1 
ATOM 1839 C C   . LEU C 3 22  ? 108.573 134.200 131.462 1.00 78.17  ? 21  LEU C C   1 
ATOM 1840 O O   . LEU C 3 22  ? 109.577 134.374 130.767 1.00 78.17  ? 21  LEU C O   1 
ATOM 1841 C CB  . LEU C 3 22  ? 108.240 131.816 132.260 1.00 78.17  ? 21  LEU C CB  1 
ATOM 1842 C CG  . LEU C 3 22  ? 109.659 131.264 132.101 1.00 78.17  ? 21  LEU C CG  1 
ATOM 1843 C CD1 . LEU C 3 22  ? 110.711 132.097 132.796 1.00 78.17  ? 21  LEU C CD1 1 
ATOM 1844 C CD2 . LEU C 3 22  ? 109.700 129.831 132.607 1.00 78.17  ? 21  LEU C CD2 1 
ATOM 1845 N N   . ASN C 3 23  ? 108.147 135.079 132.357 1.00 79.83  ? 22  ASN C N   1 
ATOM 1846 C CA  . ASN C 3 23  ? 108.736 136.394 132.524 1.00 79.83  ? 22  ASN C CA  1 
ATOM 1847 C C   . ASN C 3 23  ? 109.150 136.613 133.974 1.00 79.83  ? 22  ASN C C   1 
ATOM 1848 O O   . ASN C 3 23  ? 108.618 135.968 134.886 1.00 79.83  ? 22  ASN C O   1 
ATOM 1849 C CB  . ASN C 3 23  ? 107.749 137.486 132.082 1.00 79.83  ? 22  ASN C CB  1 
ATOM 1850 C CG  . ASN C 3 23  ? 106.341 137.232 132.568 1.00 79.83  ? 22  ASN C CG  1 
ATOM 1851 O OD1 . ASN C 3 23  ? 106.125 136.464 133.501 1.00 79.83  ? 22  ASN C OD1 1 
ATOM 1852 N ND2 . ASN C 3 23  ? 105.371 137.870 131.927 1.00 79.83  ? 22  ASN C ND2 1 
ATOM 1853 N N   . PRO C 3 24  ? 110.116 137.497 134.219 1.00 76.80  ? 23  PRO C N   1 
ATOM 1854 C CA  . PRO C 3 24  ? 110.612 137.689 135.584 1.00 76.80  ? 23  PRO C CA  1 
ATOM 1855 C C   . PRO C 3 24  ? 109.583 138.339 136.489 1.00 76.80  ? 23  PRO C C   1 
ATOM 1856 O O   . PRO C 3 24  ? 108.679 139.047 136.040 1.00 76.80  ? 23  PRO C O   1 
ATOM 1857 C CB  . PRO C 3 24  ? 111.828 138.600 135.392 1.00 76.80  ? 23  PRO C CB  1 
ATOM 1858 C CG  . PRO C 3 24  ? 111.553 139.311 134.121 1.00 76.80  ? 23  PRO C CG  1 
ATOM 1859 C CD  . PRO C 3 24  ? 110.880 138.299 133.251 1.00 76.80  ? 23  PRO C CD  1 
ATOM 1860 N N   . ARG C 3 25  ? 109.734 138.085 137.784 1.00 77.00  ? 24  ARG C N   1 
ATOM 1861 C CA  . ARG C 3 25  ? 108.881 138.646 138.823 1.00 77.00  ? 24  ARG C CA  1 
ATOM 1862 C C   . ARG C 3 25  ? 109.736 139.178 139.968 1.00 77.00  ? 24  ARG C C   1 
ATOM 1863 O O   . ARG C 3 25  ? 109.500 138.906 141.146 1.00 77.00  ? 24  ARG C O   1 
ATOM 1864 C CB  . ARG C 3 25  ? 107.868 137.610 139.305 1.00 77.00  ? 24  ARG C CB  1 
ATOM 1865 C CG  . ARG C 3 25  ? 106.727 138.184 140.133 1.00 77.00  ? 24  ARG C CG  1 
ATOM 1866 C CD  . ARG C 3 25  ? 105.393 137.578 139.750 1.00 77.00  ? 24  ARG C CD  1 
ATOM 1867 N NE  . ARG C 3 25  ? 105.101 137.765 138.335 1.00 77.00  ? 24  ARG C NE  1 
ATOM 1868 C CZ  . ARG C 3 25  ? 104.053 137.244 137.713 1.00 77.00  ? 24  ARG C CZ  1 
ATOM 1869 N NH1 . ARG C 3 25  ? 103.169 136.498 138.355 1.00 77.00  ? 24  ARG C NH1 1 
ATOM 1870 N NH2 . ARG C 3 25  ? 103.890 137.474 136.414 1.00 77.00  ? 24  ARG C NH2 1 
ATOM 1871 N N   . GLY C 3 26  ? 110.770 139.938 139.621 1.00 79.34  ? 25  GLY C N   1 
ATOM 1872 C CA  . GLY C 3 26  ? 111.573 140.619 140.615 1.00 79.34  ? 25  GLY C CA  1 
ATOM 1873 C C   . GLY C 3 26  ? 112.606 139.724 141.269 1.00 79.34  ? 25  GLY C C   1 
ATOM 1874 O O   . GLY C 3 26  ? 112.727 138.532 140.987 1.00 79.34  ? 25  GLY C O   1 
ATOM 1875 N N   . VAL C 3 27  ? 113.371 140.332 142.173 1.00 82.77  ? 26  VAL C N   1 
ATOM 1876 C CA  . VAL C 3 27  ? 114.423 139.651 142.917 1.00 82.77  ? 26  VAL C CA  1 
ATOM 1877 C C   . VAL C 3 27  ? 114.232 139.947 144.397 1.00 82.77  ? 26  VAL C C   1 
ATOM 1878 O O   . VAL C 3 27  ? 114.149 141.114 144.794 1.00 82.77  ? 26  VAL C O   1 
ATOM 1879 C CB  . VAL C 3 27  ? 115.824 140.091 142.455 1.00 82.77  ? 26  VAL C CB  1 
ATOM 1880 C CG1 . VAL C 3 27  ? 116.858 139.791 143.525 1.00 82.77  ? 26  VAL C CG1 1 
ATOM 1881 C CG2 . VAL C 3 27  ? 116.187 139.407 141.152 1.00 82.77  ? 26  VAL C CG2 1 
ATOM 1882 N N   . ASN C 3 28  ? 114.165 138.901 145.205 1.00 86.70  ? 27  ASN C N   1 
ATOM 1883 C CA  . ASN C 3 28  ? 114.004 139.072 146.644 1.00 86.70  ? 27  ASN C CA  1 
ATOM 1884 C C   . ASN C 3 28  ? 115.313 139.569 147.242 1.00 86.70  ? 27  ASN C C   1 
ATOM 1885 O O   . ASN C 3 28  ? 116.339 138.891 147.111 1.00 86.70  ? 27  ASN C O   1 
ATOM 1886 C CB  . ASN C 3 28  ? 113.583 137.750 147.282 1.00 86.70  ? 27  ASN C CB  1 
ATOM 1887 C CG  . ASN C 3 28  ? 113.520 137.816 148.798 1.00 86.70  ? 27  ASN C CG  1 
ATOM 1888 O OD1 . ASN C 3 28  ? 113.519 138.893 149.393 1.00 86.70  ? 27  ASN C OD1 1 
ATOM 1889 N ND2 . ASN C 3 28  ? 113.472 136.651 149.433 1.00 86.70  ? 27  ASN C ND2 1 
ATOM 1890 N N   . PRO C 3 29  ? 115.332 140.733 147.899 1.00 87.17  ? 28  PRO C N   1 
ATOM 1891 C CA  . PRO C 3 29  ? 116.591 141.225 148.478 1.00 87.17  ? 28  PRO C CA  1 
ATOM 1892 C C   . PRO C 3 29  ? 117.024 140.497 149.737 1.00 87.17  ? 28  PRO C C   1 
ATOM 1893 O O   . PRO C 3 29  ? 118.203 140.587 150.103 1.00 87.17  ? 28  PRO C O   1 
ATOM 1894 C CB  . PRO C 3 29  ? 116.284 142.697 148.779 1.00 87.17  ? 28  PRO C CB  1 
ATOM 1895 C CG  . PRO C 3 29  ? 114.813 142.720 149.004 1.00 87.17  ? 28  PRO C CG  1 
ATOM 1896 C CD  . PRO C 3 29  ? 114.233 141.699 148.064 1.00 87.17  ? 28  PRO C CD  1 
ATOM 1897 N N   . THR C 3 30  ? 116.116 139.790 150.412 1.00 90.19  ? 29  THR C N   1 
ATOM 1898 C CA  . THR C 3 30  ? 116.466 139.148 151.676 1.00 90.19  ? 29  THR C CA  1 
ATOM 1899 C C   . THR C 3 30  ? 117.508 138.052 151.479 1.00 90.19  ? 29  THR C C   1 
ATOM 1900 O O   . THR C 3 30  ? 118.483 137.972 152.234 1.00 90.19  ? 29  THR C O   1 
ATOM 1901 C CB  . THR C 3 30  ? 115.210 138.583 152.340 1.00 90.19  ? 29  THR C CB  1 
ATOM 1902 O OG1 . THR C 3 30  ? 114.405 139.660 152.833 1.00 90.19  ? 29  THR C OG1 1 
ATOM 1903 C CG2 . THR C 3 30  ? 115.580 137.666 153.496 1.00 90.19  ? 29  THR C CG2 1 
ATOM 1904 N N   . ASN C 3 31  ? 117.327 137.206 150.463 1.00 89.35  ? 30  ASN C N   1 
ATOM 1905 C CA  . ASN C 3 31  ? 118.230 136.087 150.223 1.00 89.35  ? 30  ASN C CA  1 
ATOM 1906 C C   . ASN C 3 31  ? 118.697 135.999 148.774 1.00 89.35  ? 30  ASN C C   1 
ATOM 1907 O O   . ASN C 3 31  ? 119.353 135.017 148.408 1.00 89.35  ? 30  ASN C O   1 
ATOM 1908 C CB  . ASN C 3 31  ? 117.568 134.771 150.642 1.00 89.35  ? 30  ASN C CB  1 
ATOM 1909 C CG  . ASN C 3 31  ? 116.152 134.648 150.131 1.00 89.35  ? 30  ASN C CG  1 
ATOM 1910 O OD1 . ASN C 3 31  ? 115.915 134.642 148.926 1.00 89.35  ? 30  ASN C OD1 1 
ATOM 1911 N ND2 . ASN C 3 31  ? 115.198 134.555 151.048 1.00 89.35  ? 30  ASN C ND2 1 
ATOM 1912 N N   . GLY C 3 32  ? 118.381 136.991 147.946 1.00 84.55  ? 31  GLY C N   1 
ATOM 1913 C CA  . GLY C 3 32  ? 118.905 137.057 146.596 1.00 84.55  ? 31  GLY C CA  1 
ATOM 1914 C C   . GLY C 3 32  ? 118.476 135.945 145.662 1.00 84.55  ? 31  GLY C C   1 
ATOM 1915 O O   . GLY C 3 32  ? 119.310 135.380 144.950 1.00 84.55  ? 31  GLY C O   1 
ATOM 1916 N N   . VAL C 3 33  ? 117.187 135.619 145.646 1.00 78.49  ? 32  VAL C N   1 
ATOM 1917 C CA  . VAL C 3 33  ? 116.636 134.650 144.705 1.00 78.49  ? 32  VAL C CA  1 
ATOM 1918 C C   . VAL C 3 33  ? 115.958 135.405 143.572 1.00 78.49  ? 32  VAL C C   1 
ATOM 1919 O O   . VAL C 3 33  ? 115.234 136.381 143.802 1.00 78.49  ? 32  VAL C O   1 
ATOM 1920 C CB  . VAL C 3 33  ? 115.653 133.680 145.391 1.00 78.49  ? 32  VAL C CB  1 
ATOM 1921 C CG1 . VAL C 3 33  ? 116.380 132.805 146.391 1.00 78.49  ? 32  VAL C CG1 1 
ATOM 1922 C CG2 . VAL C 3 33  ? 114.526 134.436 146.068 1.00 78.49  ? 32  VAL C CG2 1 
ATOM 1923 N N   . ALA C 3 34  ? 116.211 134.971 142.344 1.00 71.56  ? 33  ALA C N   1 
ATOM 1924 C CA  . ALA C 3 34  ? 115.593 135.561 141.165 1.00 71.56  ? 33  ALA C CA  1 
ATOM 1925 C C   . ALA C 3 34  ? 114.424 134.684 140.745 1.00 71.56  ? 33  ALA C C   1 
ATOM 1926 O O   . ALA C 3 34  ? 114.600 133.486 140.501 1.00 71.56  ? 33  ALA C O   1 
ATOM 1927 C CB  . ALA C 3 34  ? 116.601 135.702 140.027 1.00 71.56  ? 33  ALA C CB  1 
ATOM 1928 N N   . SER C 3 35  ? 113.241 135.278 140.659 1.00 72.06  ? 34  SER C N   1 
ATOM 1929 C CA  . SER C 3 35  ? 112.021 134.544 140.370 1.00 72.06  ? 34  SER C CA  1 
ATOM 1930 C C   . SER C 3 35  ? 111.576 134.767 138.930 1.00 72.06  ? 34  SER C C   1 
ATOM 1931 O O   . SER C 3 35  ? 111.863 135.793 138.312 1.00 72.06  ? 34  SER C O   1 
ATOM 1932 C CB  . SER C 3 35  ? 110.900 134.955 141.327 1.00 72.06  ? 34  SER C CB  1 
ATOM 1933 O OG  . SER C 3 35  ? 111.233 134.639 142.666 1.00 72.06  ? 34  SER C OG  1 
ATOM 1934 N N   . LEU C 3 36  ? 110.873 133.771 138.402 1.00 70.69  ? 35  LEU C N   1 
ATOM 1935 C CA  . LEU C 3 36  ? 110.279 133.827 137.078 1.00 70.69  ? 35  LEU C CA  1 
ATOM 1936 C C   . LEU C 3 36  ? 108.964 133.071 137.143 1.00 70.69  ? 35  LEU C C   1 
ATOM 1937 O O   . LEU C 3 36  ? 108.831 132.114 137.907 1.00 70.69  ? 35  LEU C O   1 
ATOM 1938 C CB  . LEU C 3 36  ? 111.192 133.200 136.023 1.00 70.69  ? 35  LEU C CB  1 
ATOM 1939 C CG  . LEU C 3 36  ? 112.637 133.672 135.879 1.00 70.69  ? 35  LEU C CG  1 
ATOM 1940 C CD1 . LEU C 3 36  ? 113.494 132.546 135.341 1.00 70.69  ? 35  LEU C CD1 1 
ATOM 1941 C CD2 . LEU C 3 36  ? 112.714 134.863 134.955 1.00 70.69  ? 35  LEU C CD2 1 
ATOM 1942 N N   . SER C 3 37  ? 107.994 133.488 136.333 1.00 78.00  ? 36  SER C N   1 
ATOM 1943 C CA  . SER C 3 37  ? 106.698 132.828 136.381 1.00 78.00  ? 36  SER C CA  1 
ATOM 1944 C C   . SER C 3 37  ? 105.984 132.969 135.048 1.00 78.00  ? 36  SER C C   1 
ATOM 1945 O O   . SER C 3 37  ? 106.321 133.821 134.224 1.00 78.00  ? 36  SER C O   1 
ATOM 1946 C CB  . SER C 3 37  ? 105.827 133.388 137.507 1.00 78.00  ? 36  SER C CB  1 
ATOM 1947 O OG  . SER C 3 37  ? 105.624 134.776 137.336 1.00 78.00  ? 36  SER C OG  1 
ATOM 1948 N N   . GLN C 3 38  ? 104.992 132.109 134.848 1.00 80.55  ? 37  GLN C N   1 
ATOM 1949 C CA  . GLN C 3 38  ? 104.151 132.164 133.664 1.00 80.55  ? 37  GLN C CA  1 
ATOM 1950 C C   . GLN C 3 38  ? 102.990 133.125 133.885 1.00 80.55  ? 37  GLN C C   1 
ATOM 1951 O O   . GLN C 3 38  ? 102.505 133.298 135.006 1.00 80.55  ? 37  GLN C O   1 
ATOM 1952 C CB  . GLN C 3 38  ? 103.619 130.773 133.322 1.00 80.55  ? 37  GLN C CB  1 
ATOM 1953 C CG  . GLN C 3 38  ? 102.943 130.675 131.971 1.00 80.55  ? 37  GLN C CG  1 
ATOM 1954 C CD  . GLN C 3 38  ? 102.172 129.383 131.802 1.00 80.55  ? 37  GLN C CD  1 
ATOM 1955 O OE1 . GLN C 3 38  ? 101.624 128.845 132.763 1.00 80.55  ? 37  GLN C OE1 1 
ATOM 1956 N NE2 . GLN C 3 38  ? 102.118 128.883 130.575 1.00 80.55  ? 37  GLN C NE2 1 
ATOM 1957 N N   . ALA C 3 39  ? 102.546 133.755 132.798 1.00 84.75  ? 38  ALA C N   1 
ATOM 1958 C CA  . ALA C 3 39  ? 101.434 134.705 132.850 1.00 84.75  ? 38  ALA C CA  1 
ATOM 1959 C C   . ALA C 3 39  ? 100.124 133.922 132.819 1.00 84.75  ? 38  ALA C C   1 
ATOM 1960 O O   . ALA C 3 39  ? 99.412  133.865 131.813 1.00 84.75  ? 38  ALA C O   1 
ATOM 1961 C CB  . ALA C 3 39  ? 101.525 135.701 131.703 1.00 84.75  ? 38  ALA C CB  1 
ATOM 1962 N N   . GLY C 3 40  ? 99.802  133.310 133.955 1.00 87.29  ? 39  GLY C N   1 
ATOM 1963 C CA  . GLY C 3 40  ? 98.635  132.467 134.083 1.00 87.29  ? 39  GLY C CA  1 
ATOM 1964 C C   . GLY C 3 40  ? 97.346  133.164 134.445 1.00 87.29  ? 39  GLY C C   1 
ATOM 1965 O O   . GLY C 3 40  ? 96.329  132.490 134.640 1.00 87.29  ? 39  GLY C O   1 
ATOM 1966 N N   . ALA C 3 41  ? 97.359  134.492 134.566 1.00 87.65  ? 40  ALA C N   1 
ATOM 1967 C CA  . ALA C 3 41  ? 96.209  135.346 134.853 1.00 87.65  ? 40  ALA C CA  1 
ATOM 1968 C C   . ALA C 3 41  ? 95.655  135.156 136.260 1.00 87.65  ? 40  ALA C C   1 
ATOM 1969 O O   . ALA C 3 41  ? 94.726  135.876 136.642 1.00 87.65  ? 40  ALA C O   1 
ATOM 1970 C CB  . ALA C 3 41  ? 95.067  135.157 133.844 1.00 87.65  ? 40  ALA C CB  1 
ATOM 1971 N N   . VAL C 3 42  ? 96.184  134.220 137.041 1.00 84.49  ? 41  VAL C N   1 
ATOM 1972 C CA  . VAL C 3 42  ? 95.799  134.044 138.439 1.00 84.49  ? 41  VAL C CA  1 
ATOM 1973 C C   . VAL C 3 42  ? 97.071  133.803 139.242 1.00 84.49  ? 41  VAL C C   1 
ATOM 1974 O O   . VAL C 3 42  ? 97.791  132.831 138.976 1.00 84.49  ? 41  VAL C O   1 
ATOM 1975 C CB  . VAL C 3 42  ? 94.799  132.890 138.615 1.00 84.49  ? 41  VAL C CB  1 
ATOM 1976 C CG1 . VAL C 3 42  ? 94.656  132.542 140.082 1.00 84.49  ? 41  VAL C CG1 1 
ATOM 1977 C CG2 . VAL C 3 42  ? 93.450  133.258 138.028 1.00 84.49  ? 41  VAL C CG2 1 
ATOM 1978 N N   . PRO C 3 43  ? 97.392  134.657 140.216 1.00 80.33  ? 42  PRO C N   1 
ATOM 1979 C CA  . PRO C 3 43  ? 98.686  134.523 140.908 1.00 80.33  ? 42  PRO C CA  1 
ATOM 1980 C C   . PRO C 3 43  ? 98.884  133.188 141.604 1.00 80.33  ? 42  PRO C C   1 
ATOM 1981 O O   . PRO C 3 43  ? 100.013 132.685 141.650 1.00 80.33  ? 42  PRO C O   1 
ATOM 1982 C CB  . PRO C 3 43  ? 98.661  135.687 141.908 1.00 80.33  ? 42  PRO C CB  1 
ATOM 1983 C CG  . PRO C 3 43  ? 97.692  136.663 141.331 1.00 80.33  ? 42  PRO C CG  1 
ATOM 1984 C CD  . PRO C 3 43  ? 96.639  135.835 140.671 1.00 80.33  ? 42  PRO C CD  1 
ATOM 1985 N N   . ALA C 3 44  ? 97.822  132.597 142.155 1.00 80.91  ? 43  ALA C N   1 
ATOM 1986 C CA  . ALA C 3 44  ? 97.980  131.339 142.879 1.00 80.91  ? 43  ALA C CA  1 
ATOM 1987 C C   . ALA C 3 44  ? 98.336  130.193 141.941 1.00 80.91  ? 43  ALA C C   1 
ATOM 1988 O O   . ALA C 3 44  ? 99.186  129.358 142.269 1.00 80.91  ? 43  ALA C O   1 
ATOM 1989 C CB  . ALA C 3 44  ? 96.706  131.017 143.658 1.00 80.91  ? 43  ALA C CB  1 
ATOM 1990 N N   . LEU C 3 45  ? 97.700  130.134 140.772 1.00 84.15  ? 44  LEU C N   1 
ATOM 1991 C CA  . LEU C 3 45  ? 97.904  129.043 139.820 1.00 84.15  ? 44  LEU C CA  1 
ATOM 1992 C C   . LEU C 3 45  ? 98.893  129.506 138.754 1.00 84.15  ? 44  LEU C C   1 
ATOM 1993 O O   . LEU C 3 45  ? 98.526  129.846 137.630 1.00 84.15  ? 44  LEU C O   1 
ATOM 1994 C CB  . LEU C 3 45  ? 96.577  128.618 139.205 1.00 84.15  ? 44  LEU C CB  1 
ATOM 1995 C CG  . LEU C 3 45  ? 95.377  128.580 140.149 1.00 84.15  ? 44  LEU C CG  1 
ATOM 1996 C CD1 . LEU C 3 45  ? 94.114  128.237 139.386 1.00 84.15  ? 44  LEU C CD1 1 
ATOM 1997 C CD2 . LEU C 3 45  ? 95.612  127.582 141.261 1.00 84.15  ? 44  LEU C CD2 1 
ATOM 1998 N N   . GLU C 3 46  ? 100.172 129.513 139.119 1.00 81.08  ? 45  GLU C N   1 
ATOM 1999 C CA  . GLU C 3 46  ? 101.216 129.963 138.209 1.00 81.08  ? 45  GLU C CA  1 
ATOM 2000 C C   . GLU C 3 46  ? 102.458 129.107 138.385 1.00 81.08  ? 45  GLU C C   1 
ATOM 2001 O O   . GLU C 3 46  ? 102.959 128.954 139.502 1.00 81.08  ? 45  GLU C O   1 
ATOM 2002 C CB  . GLU C 3 46  ? 101.558 131.437 138.446 1.00 81.08  ? 45  GLU C CB  1 
ATOM 2003 C CG  . GLU C 3 46  ? 100.721 132.403 137.629 1.00 81.08  ? 45  GLU C CG  1 
ATOM 2004 C CD  . GLU C 3 46  ? 101.143 133.847 137.822 1.00 81.08  ? 45  GLU C CD  1 
ATOM 2005 O OE1 . GLU C 3 46  ? 101.773 134.149 138.857 1.00 81.08  ? 45  GLU C OE1 1 
ATOM 2006 O OE2 . GLU C 3 46  ? 100.842 134.680 136.942 1.00 81.08  ? 45  GLU C OE2 1 
ATOM 2007 N N   . LYS C 3 47  ? 102.950 128.555 137.280 1.00 76.42  ? 46  LYS C N   1 
ATOM 2008 C CA  . LYS C 3 47  ? 104.199 127.810 137.300 1.00 76.42  ? 46  LYS C CA  1 
ATOM 2009 C C   . LYS C 3 47  ? 105.353 128.772 137.541 1.00 76.42  ? 46  LYS C C   1 
ATOM 2010 O O   . LYS C 3 47  ? 105.460 129.798 136.864 1.00 76.42  ? 46  LYS C O   1 
ATOM 2011 C CB  . LYS C 3 47  ? 104.385 127.081 135.974 1.00 76.42  ? 46  LYS C CB  1 
ATOM 2012 C CG  . LYS C 3 47  ? 103.357 125.998 135.724 1.00 76.42  ? 46  LYS C CG  1 
ATOM 2013 C CD  . LYS C 3 47  ? 103.601 125.303 134.400 1.00 76.42  ? 46  LYS C CD  1 
ATOM 2014 C CE  . LYS C 3 47  ? 102.624 124.163 134.199 1.00 76.42  ? 46  LYS C CE  1 
ATOM 2015 N NZ  . LYS C 3 47  ? 101.231 124.663 134.045 1.00 76.42  ? 46  LYS C NZ  1 
ATOM 2016 N N   . ARG C 3 48  ? 106.221 128.454 138.499 1.00 67.75  ? 47  ARG C N   1 
ATOM 2017 C CA  . ARG C 3 48  ? 107.274 129.389 138.870 1.00 67.75  ? 47  ARG C CA  1 
ATOM 2018 C C   . ARG C 3 48  ? 108.621 128.692 138.986 1.00 67.75  ? 47  ARG C C   1 
ATOM 2019 O O   . ARG C 3 48  ? 108.704 127.494 139.270 1.00 67.75  ? 47  ARG C O   1 
ATOM 2020 C CB  . ARG C 3 48  ? 106.947 130.111 140.179 1.00 67.75  ? 47  ARG C CB  1 
ATOM 2021 C CG  . ARG C 3 48  ? 106.860 129.220 141.395 1.00 67.75  ? 47  ARG C CG  1 
ATOM 2022 C CD  . ARG C 3 48  ? 106.505 129.955 142.702 1.00 67.75  ? 47  ARG C CD  1 
ATOM 2023 N NE  . ARG C 3 48  ? 105.214 130.641 142.698 1.00 67.75  ? 47  ARG C NE  1 
ATOM 2024 C CZ  . ARG C 3 48  ? 104.968 131.827 142.154 1.00 67.75  ? 47  ARG C CZ  1 
ATOM 2025 N NH1 . ARG C 3 48  ? 105.935 132.576 141.651 1.00 67.75  ? 47  ARG C NH1 1 
ATOM 2026 N NH2 . ARG C 3 48  ? 103.721 132.288 142.146 1.00 67.75  ? 47  ARG C NH2 1 
ATOM 2027 N N   . VAL C 3 49  ? 109.675 129.469 138.751 1.00 59.69  ? 48  VAL C N   1 
ATOM 2028 C CA  . VAL C 3 49  ? 111.054 128.995 138.773 1.00 59.69  ? 48  VAL C CA  1 
ATOM 2029 C C   . VAL C 3 49  ? 111.904 130.021 139.506 1.00 59.69  ? 48  VAL C C   1 
ATOM 2030 O O   . VAL C 3 49  ? 111.893 131.203 139.152 1.00 59.69  ? 48  VAL C O   1 
ATOM 2031 C CB  . VAL C 3 49  ? 111.600 128.780 137.350 1.00 59.69  ? 48  VAL C CB  1 
ATOM 2032 C CG1 . VAL C 3 49  ? 113.097 128.557 137.391 1.00 59.69  ? 48  VAL C CG1 1 
ATOM 2033 C CG2 . VAL C 3 49  ? 110.891 127.624 136.673 1.00 59.69  ? 48  VAL C CG2 1 
ATOM 2034 N N   . THR C 3 50  ? 112.657 129.580 140.508 1.00 60.22  ? 49  THR C N   1 
ATOM 2035 C CA  . THR C 3 50  ? 113.531 130.464 141.269 1.00 60.22  ? 49  THR C CA  1 
ATOM 2036 C C   . THR C 3 50  ? 114.967 129.977 141.159 1.00 60.22  ? 49  THR C C   1 
ATOM 2037 O O   . THR C 3 50  ? 115.245 128.800 141.403 1.00 60.22  ? 49  THR C O   1 
ATOM 2038 C CB  . THR C 3 50  ? 113.115 130.533 142.739 1.00 60.22  ? 49  THR C CB  1 
ATOM 2039 O OG1 . THR C 3 50  ? 113.526 129.335 143.407 1.00 60.22  ? 49  THR C OG1 1 
ATOM 2040 C CG2 . THR C 3 50  ? 111.608 130.680 142.861 1.00 60.22  ? 49  THR C CG2 1 
ATOM 2041 N N   . VAL C 3 51  ? 115.874 130.881 140.805 1.00 60.06  ? 50  VAL C N   1 
ATOM 2042 C CA  . VAL C 3 51  ? 117.288 130.564 140.640 1.00 60.06  ? 50  VAL C CA  1 
ATOM 2043 C C   . VAL C 3 51  ? 118.108 131.485 141.534 1.00 60.06  ? 50  VAL C C   1 
ATOM 2044 O O   . VAL C 3 51  ? 117.840 132.688 141.611 1.00 60.06  ? 50  VAL C O   1 
ATOM 2045 C CB  . VAL C 3 51  ? 117.724 130.679 139.164 1.00 60.06  ? 50  VAL C CB  1 
ATOM 2046 C CG1 . VAL C 3 51  ? 117.453 132.071 138.626 1.00 60.06  ? 50  VAL C CG1 1 
ATOM 2047 C CG2 . VAL C 3 51  ? 119.193 130.334 139.017 1.00 60.06  ? 50  VAL C CG2 1 
ATOM 2048 N N   . SER C 3 52  ? 119.093 130.916 142.228 1.00 65.07  ? 51  SER C N   1 
ATOM 2049 C CA  . SER C 3 52  ? 119.905 131.711 143.142 1.00 65.07  ? 51  SER C CA  1 
ATOM 2050 C C   . SER C 3 52  ? 121.288 131.099 143.295 1.00 65.07  ? 51  SER C C   1 
ATOM 2051 O O   . SER C 3 52  ? 121.409 129.894 143.523 1.00 65.07  ? 51  SER C O   1 
ATOM 2052 C CB  . SER C 3 52  ? 119.236 131.815 144.513 1.00 65.07  ? 51  SER C CB  1 
ATOM 2053 O OG  . SER C 3 52  ? 119.534 130.682 145.307 1.00 65.07  ? 51  SER C OG  1 
ATOM 2054 N N   . VAL C 3 53  ? 122.322 131.930 143.204 1.00 66.74  ? 52  VAL C N   1 
ATOM 2055 C CA  . VAL C 3 53  ? 123.697 131.493 143.408 1.00 66.74  ? 52  VAL C CA  1 
ATOM 2056 C C   . VAL C 3 53  ? 124.225 132.154 144.672 1.00 66.74  ? 52  VAL C C   1 
ATOM 2057 O O   . VAL C 3 53  ? 123.923 133.320 144.950 1.00 66.74  ? 52  VAL C O   1 
ATOM 2058 C CB  . VAL C 3 53  ? 124.597 131.817 142.201 1.00 66.74  ? 52  VAL C CB  1 
ATOM 2059 C CG1 . VAL C 3 53  ? 124.085 131.116 140.958 1.00 66.74  ? 52  VAL C CG1 1 
ATOM 2060 C CG2 . VAL C 3 53  ? 124.695 133.297 141.984 1.00 66.74  ? 52  VAL C CG2 1 
ATOM 2061 N N   . SER C 3 54  ? 124.990 131.400 145.453 1.00 75.23  ? 53  SER C N   1 
ATOM 2062 C CA  . SER C 3 54  ? 125.520 131.901 146.708 1.00 75.23  ? 53  SER C CA  1 
ATOM 2063 C C   . SER C 3 54  ? 126.921 132.472 146.505 1.00 75.23  ? 53  SER C C   1 
ATOM 2064 O O   . SER C 3 54  ? 127.473 132.466 145.402 1.00 75.23  ? 53  SER C O   1 
ATOM 2065 C CB  . SER C 3 54  ? 125.522 130.798 147.764 1.00 75.23  ? 53  SER C CB  1 
ATOM 2066 O OG  . SER C 3 54  ? 124.240 130.650 148.347 1.00 75.23  ? 53  SER C OG  1 
ATOM 2067 N N   . GLN C 3 55  ? 127.501 132.983 147.593 1.00 86.03  ? 54  GLN C N   1 
ATOM 2068 C CA  . GLN C 3 55  ? 128.838 133.553 147.591 1.00 86.03  ? 54  GLN C CA  1 
ATOM 2069 C C   . GLN C 3 55  ? 129.559 133.016 148.823 1.00 86.03  ? 54  GLN C C   1 
ATOM 2070 O O   . GLN C 3 55  ? 129.005 133.078 149.936 1.00 86.03  ? 54  GLN C O   1 
ATOM 2071 C CB  . GLN C 3 55  ? 128.805 135.084 147.612 1.00 86.03  ? 54  GLN C CB  1 
ATOM 2072 C CG  . GLN C 3 55  ? 128.142 135.724 146.399 1.00 86.03  ? 54  GLN C CG  1 
ATOM 2073 C CD  . GLN C 3 55  ? 129.093 135.894 145.232 1.00 86.03  ? 54  GLN C CD  1 
ATOM 2074 O OE1 . GLN C 3 55  ? 130.259 136.242 145.413 1.00 86.03  ? 54  GLN C OE1 1 
ATOM 2075 N NE2 . GLN C 3 55  ? 128.597 135.653 144.025 1.00 86.03  ? 54  GLN C NE2 1 
ATOM 2076 N N   . PRO C 3 56  ? 130.782 132.488 148.673 1.00 84.98  ? 55  PRO C N   1 
ATOM 2077 C CA  . PRO C 3 56  ? 131.536 131.952 149.811 1.00 84.98  ? 55  PRO C CA  1 
ATOM 2078 C C   . PRO C 3 56  ? 131.987 133.039 150.779 1.00 84.98  ? 55  PRO C C   1 
ATOM 2079 O O   . PRO C 3 56  ? 131.918 134.214 150.422 1.00 84.98  ? 55  PRO C O   1 
ATOM 2080 C CB  . PRO C 3 56  ? 132.742 131.283 149.148 1.00 84.98  ? 55  PRO C CB  1 
ATOM 2081 C CG  . PRO C 3 56  ? 132.912 132.011 147.866 1.00 84.98  ? 55  PRO C CG  1 
ATOM 2082 C CD  . PRO C 3 56  ? 131.526 132.360 147.410 1.00 84.98  ? 55  PRO C CD  1 
ATOM 2083 N N   . ASN C 3 62  ? 132.970 127.924 148.298 1.00 76.49  ? 61  ASN C N   1 
ATOM 2084 C CA  . ASN C 3 62  ? 131.984 126.910 147.951 1.00 76.49  ? 61  ASN C CA  1 
ATOM 2085 C C   . ASN C 3 62  ? 130.757 127.530 147.301 1.00 76.49  ? 61  ASN C C   1 
ATOM 2086 O O   . ASN C 3 62  ? 129.729 127.710 147.950 1.00 76.49  ? 61  ASN C O   1 
ATOM 2087 C CB  . ASN C 3 62  ? 131.571 126.120 149.191 1.00 76.49  ? 61  ASN C CB  1 
ATOM 2088 C CG  . ASN C 3 62  ? 132.445 124.911 149.427 1.00 76.49  ? 61  ASN C CG  1 
ATOM 2089 O OD1 . ASN C 3 62  ? 132.043 123.780 149.160 1.00 76.49  ? 61  ASN C OD1 1 
ATOM 2090 N ND2 . ASN C 3 62  ? 133.650 125.143 149.930 1.00 76.49  ? 61  ASN C ND2 1 
ATOM 2091 N N   . TYR C 3 63  ? 130.870 127.862 146.018 1.00 70.60  ? 62  TYR C N   1 
ATOM 2092 C CA  . TYR C 3 63  ? 129.730 128.398 145.292 1.00 70.60  ? 62  TYR C CA  1 
ATOM 2093 C C   . TYR C 3 63  ? 128.628 127.354 145.199 1.00 70.60  ? 62  TYR C C   1 
ATOM 2094 O O   . TYR C 3 63  ? 128.881 126.186 144.898 1.00 70.60  ? 62  TYR C O   1 
ATOM 2095 C CB  . TYR C 3 63  ? 130.154 128.846 143.896 1.00 70.60  ? 62  TYR C CB  1 
ATOM 2096 C CG  . TYR C 3 63  ? 131.097 130.022 143.902 1.00 70.60  ? 62  TYR C CG  1 
ATOM 2097 C CD1 . TYR C 3 63  ? 130.614 131.320 143.874 1.00 70.60  ? 62  TYR C CD1 1 
ATOM 2098 C CD2 . TYR C 3 63  ? 132.468 129.835 143.942 1.00 70.60  ? 62  TYR C CD2 1 
ATOM 2099 C CE1 . TYR C 3 63  ? 131.469 132.398 143.881 1.00 70.60  ? 62  TYR C CE1 1 
ATOM 2100 C CE2 . TYR C 3 63  ? 133.333 130.907 143.950 1.00 70.60  ? 62  TYR C CE2 1 
ATOM 2101 C CZ  . TYR C 3 63  ? 132.828 132.187 143.920 1.00 70.60  ? 62  TYR C CZ  1 
ATOM 2102 O OH  . TYR C 3 63  ? 133.684 133.262 143.927 1.00 70.60  ? 62  TYR C OH  1 
ATOM 2103 N N   . LYS C 3 64  ? 127.398 127.780 145.465 1.00 62.78  ? 63  LYS C N   1 
ATOM 2104 C CA  . LYS C 3 64  ? 126.243 126.896 145.450 1.00 62.78  ? 63  LYS C CA  1 
ATOM 2105 C C   . LYS C 3 64  ? 125.162 127.511 144.580 1.00 62.78  ? 63  LYS C C   1 
ATOM 2106 O O   . LYS C 3 64  ? 124.806 128.679 144.763 1.00 62.78  ? 63  LYS C O   1 
ATOM 2107 C CB  . LYS C 3 64  ? 125.716 126.658 146.866 1.00 62.78  ? 63  LYS C CB  1 
ATOM 2108 C CG  . LYS C 3 64  ? 124.610 125.630 146.949 1.00 62.78  ? 63  LYS C CG  1 
ATOM 2109 C CD  . LYS C 3 64  ? 124.146 125.446 148.380 1.00 62.78  ? 63  LYS C CD  1 
ATOM 2110 C CE  . LYS C 3 64  ? 125.231 124.803 149.224 1.00 62.78  ? 63  LYS C CE  1 
ATOM 2111 N NZ  . LYS C 3 64  ? 125.484 123.395 148.818 1.00 62.78  ? 63  LYS C NZ  1 
ATOM 2112 N N   . VAL C 3 65  ? 124.638 126.728 143.645 1.00 55.76  ? 64  VAL C N   1 
ATOM 2113 C CA  . VAL C 3 65  ? 123.617 127.182 142.708 1.00 55.76  ? 64  VAL C CA  1 
ATOM 2114 C C   . VAL C 3 65  ? 122.366 126.358 142.952 1.00 55.76  ? 64  VAL C C   1 
ATOM 2115 O O   . VAL C 3 65  ? 122.412 125.126 142.885 1.00 55.76  ? 64  VAL C O   1 
ATOM 2116 C CB  . VAL C 3 65  ? 124.080 127.046 141.251 1.00 55.76  ? 64  VAL C CB  1 
ATOM 2117 C CG1 . VAL C 3 65  ? 122.994 127.524 140.306 1.00 55.76  ? 64  VAL C CG1 1 
ATOM 2118 C CG2 . VAL C 3 65  ? 125.374 127.805 141.033 1.00 55.76  ? 64  VAL C CG2 1 
ATOM 2119 N N   . GLN C 3 66  ? 121.250 127.025 143.226 1.00 57.72  ? 65  GLN C N   1 
ATOM 2120 C CA  . GLN C 3 66  ? 120.004 126.348 143.548 1.00 57.72  ? 65  GLN C CA  1 
ATOM 2121 C C   . GLN C 3 66  ? 118.913 126.797 142.589 1.00 57.72  ? 65  GLN C C   1 
ATOM 2122 O O   . GLN C 3 66  ? 118.713 128.000 142.386 1.00 57.72  ? 65  GLN C O   1 
ATOM 2123 C CB  . GLN C 3 66  ? 119.589 126.622 144.992 1.00 57.72  ? 65  GLN C CB  1 
ATOM 2124 C CG  . GLN C 3 66  ? 118.500 125.699 145.493 1.00 57.72  ? 65  GLN C CG  1 
ATOM 2125 C CD  . GLN C 3 66  ? 118.451 125.628 147.002 1.00 57.72  ? 65  GLN C CD  1 
ATOM 2126 O OE1 . GLN C 3 66  ? 119.257 126.253 147.690 1.00 57.72  ? 65  GLN C OE1 1 
ATOM 2127 N NE2 . GLN C 3 66  ? 117.502 124.864 147.527 1.00 57.72  ? 65  GLN C NE2 1 
ATOM 2128 N N   . VAL C 3 67  ? 118.214 125.827 142.007 1.00 53.37  ? 66  VAL C N   1 
ATOM 2129 C CA  . VAL C 3 67  ? 117.106 126.076 141.091 1.00 53.37  ? 66  VAL C CA  1 
ATOM 2130 C C   . VAL C 3 67  ? 115.904 125.291 141.588 1.00 53.37  ? 66  VAL C C   1 
ATOM 2131 O O   . VAL C 3 67  ? 115.978 124.066 141.735 1.00 53.37  ? 66  VAL C O   1 
ATOM 2132 C CB  . VAL C 3 67  ? 117.457 125.678 139.650 1.00 53.37  ? 66  VAL C CB  1 
ATOM 2133 C CG1 . VAL C 3 67  ? 116.203 125.627 138.799 1.00 53.37  ? 66  VAL C CG1 1 
ATOM 2134 C CG2 . VAL C 3 67  ? 118.461 126.649 139.064 1.00 53.37  ? 66  VAL C CG2 1 
ATOM 2135 N N   . LYS C 3 68  ? 114.798 125.984 141.838 1.00 54.16  ? 67  LYS C N   1 
ATOM 2136 C CA  . LYS C 3 68  ? 113.589 125.371 142.373 1.00 54.16  ? 67  LYS C CA  1 
ATOM 2137 C C   . LYS C 3 68  ? 112.433 125.631 141.421 1.00 54.16  ? 67  LYS C C   1 
ATOM 2138 O O   . LYS C 3 68  ? 112.213 126.772 141.005 1.00 54.16  ? 67  LYS C O   1 
ATOM 2139 C CB  . LYS C 3 68  ? 113.275 125.909 143.767 1.00 54.16  ? 67  LYS C CB  1 
ATOM 2140 C CG  . LYS C 3 68  ? 114.218 125.402 144.840 1.00 54.16  ? 67  LYS C CG  1 
ATOM 2141 C CD  . LYS C 3 68  ? 113.556 125.411 146.205 1.00 54.16  ? 67  LYS C CD  1 
ATOM 2142 C CE  . LYS C 3 68  ? 113.417 126.826 146.737 1.00 54.16  ? 67  LYS C CE  1 
ATOM 2143 N NZ  . LYS C 3 68  ? 114.625 127.648 146.453 1.00 54.16  ? 67  LYS C NZ  1 
ATOM 2144 N N   . ILE C 3 69  ? 111.695 124.578 141.085 1.00 55.95  ? 68  ILE C N   1 
ATOM 2145 C CA  . ILE C 3 69  ? 110.582 124.647 140.147 1.00 55.95  ? 68  ILE C CA  1 
ATOM 2146 C C   . ILE C 3 69  ? 109.315 124.208 140.863 1.00 55.95  ? 68  ILE C C   1 
ATOM 2147 O O   . ILE C 3 69  ? 109.296 123.161 141.520 1.00 55.95  ? 68  ILE C O   1 
ATOM 2148 C CB  . ILE C 3 69  ? 110.839 123.771 138.908 1.00 55.95  ? 68  ILE C CB  1 
ATOM 2149 C CG1 . ILE C 3 69  ? 111.940 124.377 138.045 1.00 55.95  ? 68  ILE C CG1 1 
ATOM 2150 C CG2 . ILE C 3 69  ? 109.573 123.618 138.097 1.00 55.95  ? 68  ILE C CG2 1 
ATOM 2151 C CD1 . ILE C 3 69  ? 112.391 123.477 136.926 1.00 55.95  ? 68  ILE C CD1 1 
ATOM 2152 N N   . GLN C 3 70  ? 108.255 125.006 140.728 1.00 65.53  ? 69  GLN C N   1 
ATOM 2153 C CA  . GLN C 3 70  ? 106.969 124.728 141.358 1.00 65.53  ? 69  GLN C CA  1 
ATOM 2154 C C   . GLN C 3 70  ? 105.892 124.754 140.286 1.00 65.53  ? 69  GLN C C   1 
ATOM 2155 O O   . GLN C 3 70  ? 105.738 125.765 139.593 1.00 65.53  ? 69  GLN C O   1 
ATOM 2156 C CB  . GLN C 3 70  ? 106.650 125.764 142.439 1.00 65.53  ? 69  GLN C CB  1 
ATOM 2157 C CG  . GLN C 3 70  ? 107.584 125.758 143.628 1.00 65.53  ? 69  GLN C CG  1 
ATOM 2158 C CD  . GLN C 3 70  ? 107.543 124.457 144.386 1.00 65.53  ? 69  GLN C CD  1 
ATOM 2159 O OE1 . GLN C 3 70  ? 108.492 123.675 144.355 1.00 65.53  ? 69  GLN C OE1 1 
ATOM 2160 N NE2 . GLN C 3 70  ? 106.437 124.214 145.078 1.00 65.53  ? 69  GLN C NE2 1 
ATOM 2161 N N   . ASN C 3 71  ? 105.154 123.659 140.148 1.00 70.65  ? 70  ASN C N   1 
ATOM 2162 C CA  . ASN C 3 71  ? 104.021 123.607 139.223 1.00 70.65  ? 70  ASN C CA  1 
ATOM 2163 C C   . ASN C 3 71  ? 102.760 123.188 139.962 1.00 70.65  ? 70  ASN C C   1 
ATOM 2164 O O   . ASN C 3 71  ? 102.592 121.991 140.256 1.00 70.65  ? 70  ASN C O   1 
ATOM 2165 C CB  . ASN C 3 71  ? 104.298 122.642 138.072 1.00 70.65  ? 70  ASN C CB  1 
ATOM 2166 C CG  . ASN C 3 71  ? 105.570 122.972 137.330 1.00 70.65  ? 70  ASN C CG  1 
ATOM 2167 O OD1 . ASN C 3 71  ? 105.631 123.944 136.580 1.00 70.65  ? 70  ASN C OD1 1 
ATOM 2168 N ND2 . ASN C 3 71  ? 106.599 122.165 137.535 1.00 70.65  ? 70  ASN C ND2 1 
ATOM 2169 N N   . PRO C 3 72  ? 101.862 124.106 140.300 1.00 76.34  ? 71  PRO C N   1 
ATOM 2170 C CA  . PRO C 3 72  ? 100.601 123.718 140.931 1.00 76.34  ? 71  PRO C CA  1 
ATOM 2171 C C   . PRO C 3 72  ? 99.541  123.372 139.896 1.00 76.34  ? 71  PRO C C   1 
ATOM 2172 O O   . PRO C 3 72  ? 99.578  123.823 138.750 1.00 76.34  ? 71  PRO C O   1 
ATOM 2173 C CB  . PRO C 3 72  ? 100.211 124.978 141.713 1.00 76.34  ? 71  PRO C CB  1 
ATOM 2174 C CG  . PRO C 3 72  ? 100.750 126.085 140.882 1.00 76.34  ? 71  PRO C CG  1 
ATOM 2175 C CD  . PRO C 3 72  ? 102.000 125.568 140.205 1.00 76.34  ? 71  PRO C CD  1 
ATOM 2176 N N   . THR C 3 73  ? 98.581  122.556 140.325 1.00 86.50  ? 72  THR C N   1 
ATOM 2177 C CA  . THR C 3 73  ? 97.481  122.136 139.469 1.00 86.50  ? 72  THR C CA  1 
ATOM 2178 C C   . THR C 3 73  ? 96.157  122.570 140.079 1.00 86.50  ? 72  THR C C   1 
ATOM 2179 O O   . THR C 3 73  ? 95.961  122.479 141.294 1.00 86.50  ? 72  THR C O   1 
ATOM 2180 C CB  . THR C 3 73  ? 97.479  120.622 139.259 1.00 86.50  ? 72  THR C CB  1 
ATOM 2181 O OG1 . THR C 3 73  ? 97.052  119.975 140.463 1.00 86.50  ? 72  THR C OG1 1 
ATOM 2182 C CG2 . THR C 3 73  ? 98.868  120.135 138.893 1.00 86.50  ? 72  THR C CG2 1 
ATOM 2183 N N   . ALA C 3 74  ? 95.252  123.037 139.228 1.00 96.80  ? 73  ALA C N   1 
ATOM 2184 C CA  . ALA C 3 74  ? 93.975  123.569 139.669 1.00 96.80  ? 73  ALA C CA  1 
ATOM 2185 C C   . ALA C 3 74  ? 92.900  122.487 139.662 1.00 96.80  ? 73  ALA C C   1 
ATOM 2186 O O   . ALA C 3 74  ? 93.083  121.388 139.136 1.00 96.80  ? 73  ALA C O   1 
ATOM 2187 C CB  . ALA C 3 74  ? 93.553  124.738 138.782 1.00 96.80  ? 73  ALA C CB  1 
ATOM 2188 N N   . CYS C 3 75  ? 91.761  122.818 140.265 1.00 111.09 ? 74  CYS C N   1 
ATOM 2189 C CA  . CYS C 3 75  ? 90.596  121.947 140.262 1.00 111.09 ? 74  CYS C CA  1 
ATOM 2190 C C   . CYS C 3 75  ? 89.371  122.786 140.587 1.00 111.09 ? 74  CYS C C   1 
ATOM 2191 O O   . CYS C 3 75  ? 89.452  123.757 141.342 1.00 111.09 ? 74  CYS C O   1 
ATOM 2192 C CB  . CYS C 3 75  ? 90.739  120.800 141.267 1.00 111.09 ? 74  CYS C CB  1 
ATOM 2193 S SG  . CYS C 3 75  ? 90.486  121.277 142.992 1.00 111.09 ? 74  CYS C SG  1 
ATOM 2194 N N   . THR C 3 76  ? 88.238  122.404 140.006 1.00 121.18 ? 75  THR C N   1 
ATOM 2195 C CA  . THR C 3 76  ? 86.994  123.120 140.253 1.00 121.18 ? 75  THR C CA  1 
ATOM 2196 C C   . THR C 3 76  ? 86.464  122.764 141.636 1.00 121.18 ? 75  THR C C   1 
ATOM 2197 O O   . THR C 3 76  ? 86.082  121.616 141.886 1.00 121.18 ? 75  THR C O   1 
ATOM 2198 C CB  . THR C 3 76  ? 85.963  122.785 139.180 1.00 121.18 ? 75  THR C CB  1 
ATOM 2199 O OG1 . THR C 3 76  ? 86.457  123.195 137.898 1.00 121.18 ? 75  THR C OG1 1 
ATOM 2200 C CG2 . THR C 3 76  ? 84.653  123.501 139.464 1.00 121.18 ? 75  THR C CG2 1 
ATOM 2201 N N   . ALA C 3 77  ? 86.444  123.745 142.532 1.00 127.56 ? 76  ALA C N   1 
ATOM 2202 C CA  . ALA C 3 77  ? 85.978  123.508 143.890 1.00 127.56 ? 76  ALA C CA  1 
ATOM 2203 C C   . ALA C 3 77  ? 84.488  123.197 143.898 1.00 127.56 ? 76  ALA C C   1 
ATOM 2204 O O   . ALA C 3 77  ? 83.704  123.810 143.169 1.00 127.56 ? 76  ALA C O   1 
ATOM 2205 C CB  . ALA C 3 77  ? 86.267  124.722 144.772 1.00 127.56 ? 76  ALA C CB  1 
ATOM 2206 N N   . ASN C 3 78  ? 84.101  122.233 144.728 1.00 132.71 ? 77  ASN C N   1 
ATOM 2207 C CA  . ASN C 3 78  ? 82.701  121.846 144.848 1.00 132.71 ? 77  ASN C CA  1 
ATOM 2208 C C   . ASN C 3 78  ? 81.961  122.889 145.675 1.00 132.71 ? 77  ASN C C   1 
ATOM 2209 O O   . ASN C 3 78  ? 82.347  123.175 146.814 1.00 132.71 ? 77  ASN C O   1 
ATOM 2210 C CB  . ASN C 3 78  ? 82.584  120.463 145.484 1.00 132.71 ? 77  ASN C CB  1 
ATOM 2211 C CG  . ASN C 3 78  ? 81.249  119.801 145.200 1.00 132.71 ? 77  ASN C CG  1 
ATOM 2212 O OD1 . ASN C 3 78  ? 80.238  120.475 145.000 1.00 132.71 ? 77  ASN C OD1 1 
ATOM 2213 N ND2 . ASN C 3 78  ? 81.240  118.473 145.182 1.00 132.71 ? 77  ASN C ND2 1 
ATOM 2214 N N   . GLY C 3 79  ? 80.901  123.453 145.106 1.00 130.84 ? 78  GLY C N   1 
ATOM 2215 C CA  . GLY C 3 79  ? 80.143  124.481 145.801 1.00 130.84 ? 78  GLY C CA  1 
ATOM 2216 C C   . GLY C 3 79  ? 80.925  125.751 146.052 1.00 130.84 ? 78  GLY C C   1 
ATOM 2217 O O   . GLY C 3 79  ? 80.763  126.380 147.104 1.00 130.84 ? 78  GLY C O   1 
ATOM 2218 N N   . SER C 3 80  ? 81.775  126.142 145.106 1.00 129.00 ? 79  SER C N   1 
ATOM 2219 C CA  . SER C 3 80  ? 82.573  127.353 145.238 1.00 129.00 ? 79  SER C CA  1 
ATOM 2220 C C   . SER C 3 80  ? 83.001  127.800 143.848 1.00 129.00 ? 79  SER C C   1 
ATOM 2221 O O   . SER C 3 80  ? 82.854  127.068 142.866 1.00 129.00 ? 79  SER C O   1 
ATOM 2222 C CB  . SER C 3 80  ? 83.788  127.131 146.144 1.00 129.00 ? 79  SER C CB  1 
ATOM 2223 O OG  . SER C 3 80  ? 84.585  128.299 146.219 1.00 129.00 ? 79  SER C OG  1 
ATOM 2224 N N   . CYS C 3 81  ? 83.534  129.016 143.777 1.00 126.94 ? 80  CYS C N   1 
ATOM 2225 C CA  . CYS C 3 81  ? 83.949  129.615 142.515 1.00 126.94 ? 80  CYS C CA  1 
ATOM 2226 C C   . CYS C 3 81  ? 85.456  129.673 142.332 1.00 126.94 ? 80  CYS C C   1 
ATOM 2227 O O   . CYS C 3 81  ? 85.950  129.367 141.245 1.00 126.94 ? 80  CYS C O   1 
ATOM 2228 C CB  . CYS C 3 81  ? 83.375  131.031 142.391 1.00 126.94 ? 80  CYS C CB  1 
ATOM 2229 S SG  . CYS C 3 81  ? 81.576  131.122 142.544 1.00 126.94 ? 80  CYS C SG  1 
ATOM 2230 N N   . ASP C 3 82  ? 86.202  130.056 143.361 1.00 120.42 ? 81  ASP C N   1 
ATOM 2231 C CA  . ASP C 3 82  ? 87.646  130.198 143.230 1.00 120.42 ? 81  ASP C CA  1 
ATOM 2232 C C   . ASP C 3 82  ? 88.318  128.831 143.286 1.00 120.42 ? 81  ASP C C   1 
ATOM 2233 O O   . ASP C 3 82  ? 88.164  128.117 144.283 1.00 120.42 ? 81  ASP C O   1 
ATOM 2234 C CB  . ASP C 3 82  ? 88.195  131.104 144.326 1.00 120.42 ? 81  ASP C CB  1 
ATOM 2235 C CG  . ASP C 3 82  ? 87.750  130.680 145.712 1.00 120.42 ? 81  ASP C CG  1 
ATOM 2236 O OD1 . ASP C 3 82  ? 86.707  130.002 145.821 1.00 120.42 ? 81  ASP C OD1 1 
ATOM 2237 O OD2 . ASP C 3 82  ? 88.440  131.028 146.694 1.00 120.42 ? 81  ASP C OD2 1 
ATOM 2238 N N   . PRO C 3 83  ? 89.051  128.426 142.253 1.00 111.50 ? 82  PRO C N   1 
ATOM 2239 C CA  . PRO C 3 83  ? 89.763  127.148 142.314 1.00 111.50 ? 82  PRO C CA  1 
ATOM 2240 C C   . PRO C 3 83  ? 90.913  127.203 143.305 1.00 111.50 ? 82  PRO C C   1 
ATOM 2241 O O   . PRO C 3 83  ? 91.478  128.263 143.582 1.00 111.50 ? 82  PRO C O   1 
ATOM 2242 C CB  . PRO C 3 83  ? 90.271  126.955 140.881 1.00 111.50 ? 82  PRO C CB  1 
ATOM 2243 C CG  . PRO C 3 83  ? 90.365  128.334 140.332 1.00 111.50 ? 82  PRO C CG  1 
ATOM 2244 C CD  . PRO C 3 83  ? 89.253  129.115 140.967 1.00 111.50 ? 82  PRO C CD  1 
ATOM 2245 N N   . SER C 3 84  ? 91.254  126.036 143.843 1.00 104.20 ? 83  SER C N   1 
ATOM 2246 C CA  . SER C 3 84  ? 92.322  125.904 144.819 1.00 104.20 ? 83  SER C CA  1 
ATOM 2247 C C   . SER C 3 84  ? 93.400  124.969 144.288 1.00 104.20 ? 83  SER C C   1 
ATOM 2248 O O   . SER C 3 84  ? 93.161  124.153 143.394 1.00 104.20 ? 83  SER C O   1 
ATOM 2249 C CB  . SER C 3 84  ? 91.788  125.381 146.158 1.00 104.20 ? 83  SER C CB  1 
ATOM 2250 O OG  . SER C 3 84  ? 91.058  124.181 145.979 1.00 104.20 ? 83  SER C OG  1 
ATOM 2251 N N   . VAL C 3 85  ? 94.598  125.098 144.854 1.00 96.51  ? 84  VAL C N   1 
ATOM 2252 C CA  . VAL C 3 85  ? 95.739  124.274 144.459 1.00 96.51  ? 84  VAL C CA  1 
ATOM 2253 C C   . VAL C 3 85  ? 95.539  122.883 145.056 1.00 96.51  ? 84  VAL C C   1 
ATOM 2254 O O   . VAL C 3 85  ? 95.733  122.665 146.253 1.00 96.51  ? 84  VAL C O   1 
ATOM 2255 C CB  . VAL C 3 85  ? 97.071  124.899 144.883 1.00 96.51  ? 84  VAL C CB  1 
ATOM 2256 C CG1 . VAL C 3 85  ? 97.392  126.080 143.997 1.00 96.51  ? 84  VAL C CG1 1 
ATOM 2257 C CG2 . VAL C 3 85  ? 97.012  125.369 146.329 1.00 96.51  ? 84  VAL C CG2 1 
ATOM 2258 N N   . THR C 3 86  ? 95.131  121.931 144.216 1.00 93.72  ? 85  THR C N   1 
ATOM 2259 C CA  . THR C 3 86  ? 94.951  120.562 144.686 1.00 93.72  ? 85  THR C CA  1 
ATOM 2260 C C   . THR C 3 86  ? 96.289  119.917 145.020 1.00 93.72  ? 85  THR C C   1 
ATOM 2261 O O   . THR C 3 86  ? 96.458  119.334 146.097 1.00 93.72  ? 85  THR C O   1 
ATOM 2262 C CB  . THR C 3 86  ? 94.205  119.740 143.635 1.00 93.72  ? 85  THR C CB  1 
ATOM 2263 O OG1 . THR C 3 86  ? 92.835  120.154 143.588 1.00 93.72  ? 85  THR C OG1 1 
ATOM 2264 C CG2 . THR C 3 86  ? 94.267  118.259 143.972 1.00 93.72  ? 85  THR C CG2 1 
ATOM 2265 N N   . ARG C 3 87  ? 97.258  120.022 144.115 1.00 86.42  ? 86  ARG C N   1 
ATOM 2266 C CA  . ARG C 3 87  ? 98.546  119.377 144.313 1.00 86.42  ? 86  ARG C CA  1 
ATOM 2267 C C   . ARG C 3 87  ? 99.604  120.123 143.518 1.00 86.42  ? 86  ARG C C   1 
ATOM 2268 O O   . ARG C 3 87  ? 99.322  120.694 142.460 1.00 86.42  ? 86  ARG C O   1 
ATOM 2269 C CB  . ARG C 3 87  ? 98.499  117.906 143.892 1.00 86.42  ? 86  ARG C CB  1 
ATOM 2270 C CG  . ARG C 3 87  ? 97.817  117.683 142.559 1.00 86.42  ? 86  ARG C CG  1 
ATOM 2271 C CD  . ARG C 3 87  ? 97.699  116.212 142.227 1.00 86.42  ? 86  ARG C CD  1 
ATOM 2272 N NE  . ARG C 3 87  ? 97.419  116.006 140.812 1.00 86.42  ? 86  ARG C NE  1 
ATOM 2273 C CZ  . ARG C 3 87  ? 96.201  115.980 140.288 1.00 86.42  ? 86  ARG C CZ  1 
ATOM 2274 N NH1 . ARG C 3 87  ? 95.124  116.144 141.037 1.00 86.42  ? 86  ARG C NH1 1 
ATOM 2275 N NH2 . ARG C 3 87  ? 96.062  115.785 138.980 1.00 86.42  ? 86  ARG C NH2 1 
ATOM 2276 N N   . GLN C 3 88  ? 100.831 120.087 144.028 1.00 76.99  ? 87  GLN C N   1 
ATOM 2277 C CA  . GLN C 3 88  ? 101.956 120.779 143.422 1.00 76.99  ? 87  GLN C CA  1 
ATOM 2278 C C   . GLN C 3 88  ? 103.075 119.794 143.125 1.00 76.99  ? 87  GLN C C   1 
ATOM 2279 O O   . GLN C 3 88  ? 103.376 118.917 143.940 1.00 76.99  ? 87  GLN C O   1 
ATOM 2280 C CB  . GLN C 3 88  ? 102.473 121.888 144.338 1.00 76.99  ? 87  GLN C CB  1 
ATOM 2281 C CG  . GLN C 3 88  ? 101.499 123.029 144.535 1.00 76.99  ? 87  GLN C CG  1 
ATOM 2282 C CD  . GLN C 3 88  ? 102.039 124.095 145.460 1.00 76.99  ? 87  GLN C CD  1 
ATOM 2283 O OE1 . GLN C 3 88  ? 103.127 123.955 146.017 1.00 76.99  ? 87  GLN C OE1 1 
ATOM 2284 N NE2 . GLN C 3 88  ? 101.281 125.171 145.629 1.00 76.99  ? 87  GLN C NE2 1 
ATOM 2285 N N   . ALA C 3 89  ? 103.687 119.944 141.956 1.00 68.47  ? 88  ALA C N   1 
ATOM 2286 C CA  . ALA C 3 89  ? 104.870 119.187 141.582 1.00 68.47  ? 88  ALA C CA  1 
ATOM 2287 C C   . ALA C 3 89  ? 106.102 120.038 141.849 1.00 68.47  ? 88  ALA C C   1 
ATOM 2288 O O   . ALA C 3 89  ? 106.172 121.194 141.415 1.00 68.47  ? 88  ALA C O   1 
ATOM 2289 C CB  . ALA C 3 89  ? 104.822 118.775 140.112 1.00 68.47  ? 88  ALA C CB  1 
ATOM 2290 N N   . TYR C 3 90  ? 107.062 119.464 142.562 1.00 63.43  ? 89  TYR C N   1 
ATOM 2291 C CA  . TYR C 3 90  ? 108.282 120.147 142.953 1.00 63.43  ? 89  TYR C CA  1 
ATOM 2292 C C   . TYR C 3 90  ? 109.446 119.675 142.093 1.00 63.43  ? 89  TYR C C   1 
ATOM 2293 O O   . TYR C 3 90  ? 109.421 118.590 141.511 1.00 63.43  ? 89  TYR C O   1 
ATOM 2294 C CB  . TYR C 3 90  ? 108.602 119.888 144.427 1.00 63.43  ? 89  TYR C CB  1 
ATOM 2295 C CG  . TYR C 3 90  ? 107.757 120.656 145.417 1.00 63.43  ? 89  TYR C CG  1 
ATOM 2296 C CD1 . TYR C 3 90  ? 106.372 120.641 145.341 1.00 63.43  ? 89  TYR C CD1 1 
ATOM 2297 C CD2 . TYR C 3 90  ? 108.347 121.376 146.445 1.00 63.43  ? 89  TYR C CD2 1 
ATOM 2298 C CE1 . TYR C 3 90  ? 105.600 121.334 146.251 1.00 63.43  ? 89  TYR C CE1 1 
ATOM 2299 C CE2 . TYR C 3 90  ? 107.584 122.071 147.359 1.00 63.43  ? 89  TYR C CE2 1 
ATOM 2300 C CZ  . TYR C 3 90  ? 106.211 122.046 147.258 1.00 63.43  ? 89  TYR C CZ  1 
ATOM 2301 O OH  . TYR C 3 90  ? 105.446 122.739 148.167 1.00 63.43  ? 89  TYR C OH  1 
ATOM 2302 N N   . ALA C 3 91  ? 110.471 120.516 142.012 1.00 58.00  ? 90  ALA C N   1 
ATOM 2303 C CA  . ALA C 3 91  ? 111.730 120.114 141.405 1.00 58.00  ? 90  ALA C CA  1 
ATOM 2304 C C   . ALA C 3 91  ? 112.842 120.953 142.009 1.00 58.00  ? 90  ALA C C   1 
ATOM 2305 O O   . ALA C 3 91  ? 112.648 122.138 142.277 1.00 58.00  ? 90  ALA C O   1 
ATOM 2306 C CB  . ALA C 3 91  ? 111.707 120.273 139.882 1.00 58.00  ? 90  ALA C CB  1 
ATOM 2307 N N   . ASP C 3 92  ? 114.001 120.340 142.216 1.00 57.25  ? 91  ASP C N   1 
ATOM 2308 C CA  . ASP C 3 92  ? 115.117 121.026 142.847 1.00 57.25  ? 91  ASP C CA  1 
ATOM 2309 C C   . ASP C 3 92  ? 116.421 120.588 142.203 1.00 57.25  ? 91  ASP C C   1 
ATOM 2310 O O   . ASP C 3 92  ? 116.594 119.415 141.870 1.00 57.25  ? 91  ASP C O   1 
ATOM 2311 C CB  . ASP C 3 92  ? 115.149 120.747 144.352 1.00 57.25  ? 91  ASP C CB  1 
ATOM 2312 C CG  . ASP C 3 92  ? 116.118 121.642 145.090 1.00 57.25  ? 91  ASP C CG  1 
ATOM 2313 O OD1 . ASP C 3 92  ? 117.338 121.531 144.847 1.00 57.25  ? 91  ASP C OD1 1 
ATOM 2314 O OD2 . ASP C 3 92  ? 115.660 122.457 145.918 1.00 57.25  ? 91  ASP C OD2 1 
ATOM 2315 N N   . VAL C 3 93  ? 117.327 121.543 142.017 1.00 53.49  ? 92  VAL C N   1 
ATOM 2316 C CA  . VAL C 3 93  ? 118.660 121.288 141.482 1.00 53.49  ? 92  VAL C CA  1 
ATOM 2317 C C   . VAL C 3 93  ? 119.657 122.063 142.328 1.00 53.49  ? 92  VAL C C   1 
ATOM 2318 O O   . VAL C 3 93  ? 119.439 123.244 142.617 1.00 53.49  ? 92  VAL C O   1 
ATOM 2319 C CB  . VAL C 3 93  ? 118.781 121.693 140.002 1.00 53.49  ? 92  VAL C CB  1 
ATOM 2320 C CG1 . VAL C 3 93  ? 120.193 121.467 139.509 1.00 53.49  ? 92  VAL C CG1 1 
ATOM 2321 C CG2 . VAL C 3 93  ? 117.791 120.920 139.153 1.00 53.49  ? 92  VAL C CG2 1 
ATOM 2322 N N   . THR C 3 94  ? 120.752 121.409 142.718 1.00 55.52  ? 93  THR C N   1 
ATOM 2323 C CA  . THR C 3 94  ? 121.728 121.999 143.635 1.00 55.52  ? 93  THR C CA  1 
ATOM 2324 C C   . THR C 3 94  ? 123.137 121.666 143.152 1.00 55.52  ? 93  THR C C   1 
ATOM 2325 O O   . THR C 3 94  ? 123.621 120.551 143.356 1.00 55.52  ? 93  THR C O   1 
ATOM 2326 C CB  . THR C 3 94  ? 121.509 121.500 145.057 1.00 55.52  ? 93  THR C CB  1 
ATOM 2327 O OG1 . THR C 3 94  ? 120.146 121.721 145.436 1.00 55.52  ? 93  THR C OG1 1 
ATOM 2328 C CG2 . THR C 3 94  ? 122.423 122.235 146.020 1.00 55.52  ? 93  THR C CG2 1 
ATOM 2329 N N   . PHE C 3 95  ? 123.790 122.638 142.525 1.00 56.96  ? 94  PHE C N   1 
ATOM 2330 C CA  . PHE C 3 95  ? 125.182 122.515 142.118 1.00 56.96  ? 94  PHE C CA  1 
ATOM 2331 C C   . PHE C 3 95  ? 126.086 123.060 143.214 1.00 56.96  ? 94  PHE C C   1 
ATOM 2332 O O   . PHE C 3 95  ? 125.758 124.058 143.858 1.00 56.96  ? 94  PHE C O   1 
ATOM 2333 C CB  . PHE C 3 95  ? 125.422 123.273 140.815 1.00 56.96  ? 94  PHE C CB  1 
ATOM 2334 C CG  . PHE C 3 95  ? 124.638 122.745 139.656 1.00 56.96  ? 94  PHE C CG  1 
ATOM 2335 C CD1 . PHE C 3 95  ? 124.564 121.388 139.418 1.00 56.96  ? 94  PHE C CD1 1 
ATOM 2336 C CD2 . PHE C 3 95  ? 123.965 123.603 138.811 1.00 56.96  ? 94  PHE C CD2 1 
ATOM 2337 C CE1 . PHE C 3 95  ? 123.843 120.900 138.353 1.00 56.96  ? 94  PHE C CE1 1 
ATOM 2338 C CE2 . PHE C 3 95  ? 123.240 123.118 137.746 1.00 56.96  ? 94  PHE C CE2 1 
ATOM 2339 C CZ  . PHE C 3 95  ? 123.180 121.767 137.517 1.00 56.96  ? 94  PHE C CZ  1 
ATOM 2340 N N   . SER C 3 96  ? 127.234 122.415 143.412 1.00 63.40  ? 95  SER C N   1 
ATOM 2341 C CA  . SER C 3 96  ? 128.124 122.718 144.531 1.00 63.40  ? 95  SER C CA  1 
ATOM 2342 C C   . SER C 3 96  ? 129.575 122.815 144.075 1.00 63.40  ? 95  SER C C   1 
ATOM 2343 O O   . SER C 3 96  ? 130.471 122.196 144.652 1.00 63.40  ? 95  SER C O   1 
ATOM 2344 C CB  . SER C 3 96  ? 127.987 121.675 145.633 1.00 63.40  ? 95  SER C CB  1 
ATOM 2345 O OG  . SER C 3 96  ? 129.129 121.677 146.470 1.00 63.40  ? 95  SER C OG  1 
ATOM 2346 N N   . PHE C 3 97  ? 129.832 123.596 143.029 1.00 67.64  ? 96  PHE C N   1 
ATOM 2347 C CA  . PHE C 3 97  ? 131.200 123.789 142.566 1.00 67.64  ? 96  PHE C CA  1 
ATOM 2348 C C   . PHE C 3 97  ? 132.050 124.450 143.645 1.00 67.64  ? 96  PHE C C   1 
ATOM 2349 O O   . PHE C 3 97  ? 131.572 125.276 144.425 1.00 67.64  ? 96  PHE C O   1 
ATOM 2350 C CB  . PHE C 3 97  ? 131.221 124.645 141.304 1.00 67.64  ? 96  PHE C CB  1 
ATOM 2351 C CG  . PHE C 3 97  ? 130.120 124.332 140.342 1.00 67.64  ? 96  PHE C CG  1 
ATOM 2352 C CD1 . PHE C 3 97  ? 130.078 123.115 139.692 1.00 67.64  ? 96  PHE C CD1 1 
ATOM 2353 C CD2 . PHE C 3 97  ? 129.130 125.260 140.084 1.00 67.64  ? 96  PHE C CD2 1 
ATOM 2354 C CE1 . PHE C 3 97  ? 129.068 122.827 138.802 1.00 67.64  ? 96  PHE C CE1 1 
ATOM 2355 C CE2 . PHE C 3 97  ? 128.116 124.978 139.198 1.00 67.64  ? 96  PHE C CE2 1 
ATOM 2356 C CZ  . PHE C 3 97  ? 128.085 123.760 138.555 1.00 67.64  ? 96  PHE C CZ  1 
ATOM 2357 N N   . THR C 3 98  ? 133.328 124.079 143.684 1.00 74.73  ? 97  THR C N   1 
ATOM 2358 C CA  . THR C 3 98  ? 134.255 124.606 144.673 1.00 74.73  ? 97  THR C CA  1 
ATOM 2359 C C   . THR C 3 98  ? 134.889 125.898 144.160 1.00 74.73  ? 97  THR C C   1 
ATOM 2360 O O   . THR C 3 98  ? 134.540 126.407 143.092 1.00 74.73  ? 97  THR C O   1 
ATOM 2361 C CB  . THR C 3 98  ? 135.316 123.566 145.019 1.00 74.73  ? 97  THR C CB  1 
ATOM 2362 O OG1 . THR C 3 98  ? 136.155 123.345 143.880 1.00 74.73  ? 97  THR C OG1 1 
ATOM 2363 C CG2 . THR C 3 98  ? 134.661 122.256 145.420 1.00 74.73  ? 97  THR C CG2 1 
ATOM 2364 N N   . GLN C 3 99  ? 135.841 126.440 144.923 1.00 79.67  ? 98  GLN C N   1 
ATOM 2365 C CA  . GLN C 3 99  ? 136.420 127.735 144.579 1.00 79.67  ? 98  GLN C CA  1 
ATOM 2366 C C   . GLN C 3 99  ? 137.329 127.641 143.360 1.00 79.67  ? 98  GLN C C   1 
ATOM 2367 O O   . GLN C 3 99  ? 137.309 128.527 142.498 1.00 79.67  ? 98  GLN C O   1 
ATOM 2368 C CB  . GLN C 3 99  ? 137.192 128.301 145.771 1.00 79.67  ? 98  GLN C CB  1 
ATOM 2369 C CG  . GLN C 3 99  ? 136.315 128.897 146.860 1.00 79.67  ? 98  GLN C CG  1 
ATOM 2370 C CD  . GLN C 3 99  ? 136.724 128.448 148.250 1.00 79.67  ? 98  GLN C CD  1 
ATOM 2371 O OE1 . GLN C 3 99  ? 137.896 128.169 148.504 1.00 79.67  ? 98  GLN C OE1 1 
ATOM 2372 N NE2 . GLN C 3 99  ? 135.759 128.380 149.160 1.00 79.67  ? 98  GLN C NE2 1 
ATOM 2373 N N   . TYR C 3 100 ? 138.130 126.584 143.268 1.00 79.13  ? 99  TYR C N   1 
ATOM 2374 C CA  . TYR C 3 100 ? 139.146 126.471 142.230 1.00 79.13  ? 99  TYR C CA  1 
ATOM 2375 C C   . TYR C 3 100 ? 138.653 125.771 140.971 1.00 79.13  ? 99  TYR C C   1 
ATOM 2376 O O   . TYR C 3 100 ? 139.449 125.561 140.051 1.00 79.13  ? 99  TYR C O   1 
ATOM 2377 C CB  . TYR C 3 100 ? 140.369 125.729 142.772 1.00 79.13  ? 99  TYR C CB  1 
ATOM 2378 C CG  . TYR C 3 100 ? 141.240 126.561 143.680 1.00 79.13  ? 99  TYR C CG  1 
ATOM 2379 C CD1 . TYR C 3 100 ? 140.931 126.710 145.023 1.00 79.13  ? 99  TYR C CD1 1 
ATOM 2380 C CD2 . TYR C 3 100 ? 142.374 127.194 143.196 1.00 79.13  ? 99  TYR C CD2 1 
ATOM 2381 C CE1 . TYR C 3 100 ? 141.725 127.466 145.858 1.00 79.13  ? 99  TYR C CE1 1 
ATOM 2382 C CE2 . TYR C 3 100 ? 143.174 127.954 144.023 1.00 79.13  ? 99  TYR C CE2 1 
ATOM 2383 C CZ  . TYR C 3 100 ? 142.845 128.087 145.353 1.00 79.13  ? 99  TYR C CZ  1 
ATOM 2384 O OH  . TYR C 3 100 ? 143.640 128.843 146.181 1.00 79.13  ? 99  TYR C OH  1 
ATOM 2385 N N   . SER C 3 101 ? 137.379 125.401 140.905 1.00 77.25  ? 100 SER C N   1 
ATOM 2386 C CA  . SER C 3 101 ? 136.864 124.729 139.721 1.00 77.25  ? 100 SER C CA  1 
ATOM 2387 C C   . SER C 3 101 ? 136.877 125.672 138.526 1.00 77.25  ? 100 SER C C   1 
ATOM 2388 O O   . SER C 3 101 ? 136.497 126.840 138.632 1.00 77.25  ? 100 SER C O   1 
ATOM 2389 C CB  . SER C 3 101 ? 135.446 124.224 139.968 1.00 77.25  ? 100 SER C CB  1 
ATOM 2390 O OG  . SER C 3 101 ? 134.555 125.308 140.158 1.00 77.25  ? 100 SER C OG  1 
ATOM 2391 N N   . THR C 3 102 ? 137.310 125.155 137.381 1.00 81.00  ? 101 THR C N   1 
ATOM 2392 C CA  . THR C 3 102 ? 137.386 125.954 136.171 1.00 81.00  ? 101 THR C CA  1 
ATOM 2393 C C   . THR C 3 102 ? 136.013 126.051 135.513 1.00 81.00  ? 101 THR C C   1 
ATOM 2394 O O   . THR C 3 102 ? 135.005 125.568 136.034 1.00 81.00  ? 101 THR C O   1 
ATOM 2395 C CB  . THR C 3 102 ? 138.407 125.362 135.205 1.00 81.00  ? 101 THR C CB  1 
ATOM 2396 O OG1 . THR C 3 102 ? 137.993 124.045 134.823 1.00 81.00  ? 101 THR C OG1 1 
ATOM 2397 C CG2 . THR C 3 102 ? 139.772 125.282 135.863 1.00 81.00  ? 101 THR C CG2 1 
ATOM 2398 N N   . ASP C 3 103 ? 135.972 126.695 134.347 1.00 79.66  ? 102 ASP C N   1 
ATOM 2399 C CA  . ASP C 3 103 ? 134.726 126.820 133.601 1.00 79.66  ? 102 ASP C CA  1 
ATOM 2400 C C   . ASP C 3 103 ? 134.341 125.507 132.929 1.00 79.66  ? 102 ASP C C   1 
ATOM 2401 O O   . ASP C 3 103 ? 133.153 125.163 132.878 1.00 79.66  ? 102 ASP C O   1 
ATOM 2402 C CB  . ASP C 3 103 ? 134.865 127.935 132.562 1.00 79.66  ? 102 ASP C CB  1 
ATOM 2403 C CG  . ASP C 3 103 ? 133.554 128.283 131.880 1.00 79.66  ? 102 ASP C CG  1 
ATOM 2404 O OD1 . ASP C 3 103 ? 132.520 127.652 132.175 1.00 79.66  ? 102 ASP C OD1 1 
ATOM 2405 O OD2 . ASP C 3 103 ? 133.559 129.200 131.033 1.00 79.66  ? 102 ASP C OD2 1 
ATOM 2406 N N   . GLU C 3 104 ? 135.327 124.759 132.427 1.00 81.38  ? 103 GLU C N   1 
ATOM 2407 C CA  . GLU C 3 104 ? 135.030 123.539 131.684 1.00 81.38  ? 103 GLU C CA  1 
ATOM 2408 C C   . GLU C 3 104 ? 134.331 122.507 132.557 1.00 81.38  ? 103 GLU C C   1 
ATOM 2409 O O   . GLU C 3 104 ? 133.394 121.843 132.106 1.00 81.38  ? 103 GLU C O   1 
ATOM 2410 C CB  . GLU C 3 104 ? 136.312 122.957 131.093 1.00 81.38  ? 103 GLU C CB  1 
ATOM 2411 C CG  . GLU C 3 104 ? 136.860 123.741 129.917 1.00 81.38  ? 103 GLU C CG  1 
ATOM 2412 C CD  . GLU C 3 104 ? 137.842 124.812 130.342 1.00 81.38  ? 103 GLU C CD  1 
ATOM 2413 O OE1 . GLU C 3 104 ? 138.179 124.865 131.543 1.00 81.38  ? 103 GLU C OE1 1 
ATOM 2414 O OE2 . GLU C 3 104 ? 138.277 125.600 129.476 1.00 81.38  ? 103 GLU C OE2 1 
ATOM 2415 N N   . GLU C 3 105 ? 134.770 122.351 133.808 1.00 78.73  ? 104 GLU C N   1 
ATOM 2416 C CA  . GLU C 3 105 ? 134.154 121.357 134.681 1.00 78.73  ? 104 GLU C CA  1 
ATOM 2417 C C   . GLU C 3 105 ? 132.697 121.697 134.972 1.00 78.73  ? 104 GLU C C   1 
ATOM 2418 O O   . GLU C 3 105 ? 131.824 120.820 134.929 1.00 78.73  ? 104 GLU C O   1 
ATOM 2419 C CB  . GLU C 3 105 ? 134.945 121.238 135.982 1.00 78.73  ? 104 GLU C CB  1 
ATOM 2420 C CG  . GLU C 3 105 ? 136.417 120.931 135.779 1.00 78.73  ? 104 GLU C CG  1 
ATOM 2421 C CD  . GLU C 3 105 ? 137.169 120.792 137.088 1.00 78.73  ? 104 GLU C CD  1 
ATOM 2422 O OE1 . GLU C 3 105 ? 136.548 120.983 138.154 1.00 78.73  ? 104 GLU C OE1 1 
ATOM 2423 O OE2 . GLU C 3 105 ? 138.381 120.492 137.051 1.00 78.73  ? 104 GLU C OE2 1 
ATOM 2424 N N   . ARG C 3 106 ? 132.415 122.964 135.273 1.00 73.14  ? 105 ARG C N   1 
ATOM 2425 C CA  . ARG C 3 106 ? 131.041 123.366 135.552 1.00 73.14  ? 105 ARG C CA  1 
ATOM 2426 C C   . ARG C 3 106 ? 130.162 123.219 134.318 1.00 73.14  ? 105 ARG C C   1 
ATOM 2427 O O   . ARG C 3 106 ? 129.015 122.760 134.415 1.00 73.14  ? 105 ARG C O   1 
ATOM 2428 C CB  . ARG C 3 106 ? 131.017 124.800 136.070 1.00 73.14  ? 105 ARG C CB  1 
ATOM 2429 C CG  . ARG C 3 106 ? 131.889 125.007 137.289 1.00 73.14  ? 105 ARG C CG  1 
ATOM 2430 C CD  . ARG C 3 106 ? 131.773 126.417 137.815 1.00 73.14  ? 105 ARG C CD  1 
ATOM 2431 N NE  . ARG C 3 106 ? 132.277 127.394 136.861 1.00 73.14  ? 105 ARG C NE  1 
ATOM 2432 C CZ  . ARG C 3 106 ? 133.417 128.054 137.003 1.00 73.14  ? 105 ARG C CZ  1 
ATOM 2433 N NH1 . ARG C 3 106 ? 134.194 127.869 138.056 1.00 73.14  ? 105 ARG C NH1 1 
ATOM 2434 N NH2 . ARG C 3 106 ? 133.786 128.921 136.065 1.00 73.14  ? 105 ARG C NH2 1 
ATOM 2435 N N   . ALA C 3 107 ? 130.680 123.601 133.149 1.00 70.81  ? 106 ALA C N   1 
ATOM 2436 C CA  . ALA C 3 107 ? 129.915 123.415 131.922 1.00 70.81  ? 106 ALA C CA  1 
ATOM 2437 C C   . ALA C 3 107 ? 129.647 121.940 131.668 1.00 70.81  ? 106 ALA C C   1 
ATOM 2438 O O   . ALA C 3 107 ? 128.554 121.564 131.227 1.00 70.81  ? 106 ALA C O   1 
ATOM 2439 C CB  . ALA C 3 107 ? 130.653 124.038 130.740 1.00 70.81  ? 106 ALA C CB  1 
ATOM 2440 N N   . PHE C 3 108 ? 130.634 121.087 131.945 1.00 66.97  ? 107 PHE C N   1 
ATOM 2441 C CA  . PHE C 3 108 ? 130.450 119.655 131.758 1.00 66.97  ? 107 PHE C CA  1 
ATOM 2442 C C   . PHE C 3 108 ? 129.367 119.117 132.679 1.00 66.97  ? 107 PHE C C   1 
ATOM 2443 O O   . PHE C 3 108 ? 128.535 118.310 132.257 1.00 66.97  ? 107 PHE C O   1 
ATOM 2444 C CB  . PHE C 3 108 ? 131.765 118.920 132.000 1.00 66.97  ? 107 PHE C CB  1 
ATOM 2445 C CG  . PHE C 3 108 ? 131.781 117.528 131.459 1.00 66.97  ? 107 PHE C CG  1 
ATOM 2446 C CD1 . PHE C 3 108 ? 132.049 117.298 130.124 1.00 66.97  ? 107 PHE C CD1 1 
ATOM 2447 C CD2 . PHE C 3 108 ? 131.511 116.451 132.276 1.00 66.97  ? 107 PHE C CD2 1 
ATOM 2448 C CE1 . PHE C 3 108 ? 132.060 116.019 129.617 1.00 66.97  ? 107 PHE C CE1 1 
ATOM 2449 C CE2 . PHE C 3 108 ? 131.520 115.170 131.773 1.00 66.97  ? 107 PHE C CE2 1 
ATOM 2450 C CZ  . PHE C 3 108 ? 131.796 114.953 130.443 1.00 66.97  ? 107 PHE C CZ  1 
ATOM 2451 N N   . VAL C 3 109 ? 129.359 119.553 133.939 1.00 68.11  ? 108 VAL C N   1 
ATOM 2452 C CA  . VAL C 3 109 ? 128.333 119.086 134.869 1.00 68.11  ? 108 VAL C CA  1 
ATOM 2453 C C   . VAL C 3 109 ? 126.951 119.551 134.425 1.00 68.11  ? 108 VAL C C   1 
ATOM 2454 O O   . VAL C 3 109 ? 125.981 118.780 134.455 1.00 68.11  ? 108 VAL C O   1 
ATOM 2455 C CB  . VAL C 3 109 ? 128.652 119.547 136.301 1.00 68.11  ? 108 VAL C CB  1 
ATOM 2456 C CG1 . VAL C 3 109 ? 127.462 119.311 137.206 1.00 68.11  ? 108 VAL C CG1 1 
ATOM 2457 C CG2 . VAL C 3 109 ? 129.863 118.810 136.828 1.00 68.11  ? 108 VAL C CG2 1 
ATOM 2458 N N   . ARG C 3 110 ? 126.833 120.814 134.006 1.00 67.81  ? 109 ARG C N   1 
ATOM 2459 C CA  . ARG C 3 110 ? 125.534 121.320 133.571 1.00 67.81  ? 109 ARG C CA  1 
ATOM 2460 C C   . ARG C 3 110 ? 125.030 120.564 132.349 1.00 67.81  ? 109 ARG C C   1 
ATOM 2461 O O   . ARG C 3 110 ? 123.861 120.166 132.289 1.00 67.81  ? 109 ARG C O   1 
ATOM 2462 C CB  . ARG C 3 110 ? 125.612 122.816 133.277 1.00 67.81  ? 109 ARG C CB  1 
ATOM 2463 C CG  . ARG C 3 110 ? 124.389 123.345 132.552 1.00 67.81  ? 109 ARG C CG  1 
ATOM 2464 C CD  . ARG C 3 110 ? 124.577 124.776 132.090 1.00 67.81  ? 109 ARG C CD  1 
ATOM 2465 N NE  . ARG C 3 110 ? 125.590 124.894 131.049 1.00 67.81  ? 109 ARG C NE  1 
ATOM 2466 C CZ  . ARG C 3 110 ? 125.399 124.572 129.777 1.00 67.81  ? 109 ARG C CZ  1 
ATOM 2467 N NH1 . ARG C 3 110 ? 124.247 124.080 129.354 1.00 67.81  ? 109 ARG C NH1 1 
ATOM 2468 N NH2 . ARG C 3 110 ? 126.390 124.747 128.909 1.00 67.81  ? 109 ARG C NH2 1 
ATOM 2469 N N   . THR C 3 111 ? 125.902 120.346 131.362 1.00 66.65  ? 110 THR C N   1 
ATOM 2470 C CA  . THR C 3 111 ? 125.484 119.617 130.170 1.00 66.65  ? 110 THR C CA  1 
ATOM 2471 C C   . THR C 3 111 ? 125.178 118.159 130.478 1.00 66.65  ? 110 THR C C   1 
ATOM 2472 O O   . THR C 3 111 ? 124.271 117.582 129.872 1.00 66.65  ? 110 THR C O   1 
ATOM 2473 C CB  . THR C 3 111 ? 126.552 119.719 129.085 1.00 66.65  ? 110 THR C CB  1 
ATOM 2474 O OG1 . THR C 3 111 ? 127.822 119.340 129.627 1.00 66.65  ? 110 THR C OG1 1 
ATOM 2475 C CG2 . THR C 3 111 ? 126.633 121.136 128.551 1.00 66.65  ? 110 THR C CG2 1 
ATOM 2476 N N   . GLU C 3 112 ? 125.909 117.549 131.413 1.00 65.47  ? 111 GLU C N   1 
ATOM 2477 C CA  . GLU C 3 112 ? 125.596 116.188 131.830 1.00 65.47  ? 111 GLU C CA  1 
ATOM 2478 C C   . GLU C 3 112 ? 124.202 116.113 132.427 1.00 65.47  ? 111 GLU C C   1 
ATOM 2479 O O   . GLU C 3 112 ? 123.422 115.213 132.101 1.00 65.47  ? 111 GLU C O   1 
ATOM 2480 C CB  . GLU C 3 112 ? 126.630 115.701 132.843 1.00 65.47  ? 111 GLU C CB  1 
ATOM 2481 C CG  . GLU C 3 112 ? 126.718 114.194 132.963 1.00 65.47  ? 111 GLU C CG  1 
ATOM 2482 C CD  . GLU C 3 112 ? 127.962 113.746 133.698 1.00 65.47  ? 111 GLU C CD  1 
ATOM 2483 O OE1 . GLU C 3 112 ? 129.062 114.205 133.336 1.00 65.47  ? 111 GLU C OE1 1 
ATOM 2484 O OE2 . GLU C 3 112 ? 127.840 112.936 134.640 1.00 65.47  ? 111 GLU C OE2 1 
ATOM 2485 N N   . LEU C 3 113 ? 123.868 117.058 133.305 1.00 62.42  ? 112 LEU C N   1 
ATOM 2486 C CA  . LEU C 3 113 ? 122.543 117.032 133.911 1.00 62.42  ? 112 LEU C CA  1 
ATOM 2487 C C   . LEU C 3 113 ? 121.456 117.343 132.892 1.00 62.42  ? 112 LEU C C   1 
ATOM 2488 O O   . LEU C 3 113 ? 120.341 116.824 133.001 1.00 62.42  ? 112 LEU C O   1 
ATOM 2489 C CB  . LEU C 3 113 ? 122.475 118.010 135.079 1.00 62.42  ? 112 LEU C CB  1 
ATOM 2490 C CG  . LEU C 3 113 ? 121.205 117.897 135.917 1.00 62.42  ? 112 LEU C CG  1 
ATOM 2491 C CD1 . LEU C 3 113 ? 120.984 116.456 136.340 1.00 62.42  ? 112 LEU C CD1 1 
ATOM 2492 C CD2 . LEU C 3 113 ? 121.283 118.802 137.127 1.00 62.42  ? 112 LEU C CD2 1 
ATOM 2493 N N   . ALA C 3 114 ? 121.757 118.178 131.896 1.00 64.43  ? 113 ALA C N   1 
ATOM 2494 C CA  . ALA C 3 114 ? 120.750 118.516 130.895 1.00 64.43  ? 113 ALA C CA  1 
ATOM 2495 C C   . ALA C 3 114 ? 120.521 117.380 129.906 1.00 64.43  ? 113 ALA C C   1 
ATOM 2496 O O   . ALA C 3 114 ? 119.399 117.204 129.421 1.00 64.43  ? 113 ALA C O   1 
ATOM 2497 C CB  . ALA C 3 114 ? 121.152 119.788 130.152 1.00 64.43  ? 113 ALA C CB  1 
ATOM 2498 N N   . ALA C 3 115 ? 121.560 116.609 129.586 1.00 61.78  ? 114 ALA C N   1 
ATOM 2499 C CA  . ALA C 3 115 ? 121.433 115.543 128.600 1.00 61.78  ? 114 ALA C CA  1 
ATOM 2500 C C   . ALA C 3 115 ? 120.979 114.229 129.219 1.00 61.78  ? 114 ALA C C   1 
ATOM 2501 O O   . ALA C 3 115 ? 120.183 113.505 128.613 1.00 61.78  ? 114 ALA C O   1 
ATOM 2502 C CB  . ALA C 3 115 ? 122.762 115.337 127.871 1.00 61.78  ? 114 ALA C CB  1 
ATOM 2503 N N   . LEU C 3 116 ? 121.474 113.904 130.414 1.00 61.78  ? 115 LEU C N   1 
ATOM 2504 C CA  . LEU C 3 116 ? 121.061 112.680 131.087 1.00 61.78  ? 115 LEU C CA  1 
ATOM 2505 C C   . LEU C 3 116 ? 119.581 112.707 131.438 1.00 61.78  ? 115 LEU C C   1 
ATOM 2506 O O   . LEU C 3 116 ? 118.935 111.656 131.487 1.00 61.78  ? 115 LEU C O   1 
ATOM 2507 C CB  . LEU C 3 116 ? 121.906 112.477 132.343 1.00 61.78  ? 115 LEU C CB  1 
ATOM 2508 C CG  . LEU C 3 116 ? 121.450 111.453 133.376 1.00 61.78  ? 115 LEU C CG  1 
ATOM 2509 C CD1 . LEU C 3 116 ? 121.507 110.053 132.798 1.00 61.78  ? 115 LEU C CD1 1 
ATOM 2510 C CD2 . LEU C 3 116 ? 122.308 111.560 134.619 1.00 61.78  ? 115 LEU C CD2 1 
ATOM 2511 N N   . LEU C 3 117 ? 119.027 113.894 131.669 1.00 63.49  ? 116 LEU C N   1 
ATOM 2512 C CA  . LEU C 3 117 ? 117.628 114.033 132.044 1.00 63.49  ? 116 LEU C CA  1 
ATOM 2513 C C   . LEU C 3 117 ? 116.671 113.724 130.901 1.00 63.49  ? 116 LEU C C   1 
ATOM 2514 O O   . LEU C 3 117 ? 115.466 113.600 131.143 1.00 63.49  ? 116 LEU C O   1 
ATOM 2515 C CB  . LEU C 3 117 ? 117.380 115.448 132.567 1.00 63.49  ? 116 LEU C CB  1 
ATOM 2516 C CG  . LEU C 3 117 ? 116.219 115.637 133.535 1.00 63.49  ? 116 LEU C CG  1 
ATOM 2517 C CD1 . LEU C 3 117 ? 116.576 115.059 134.888 1.00 63.49  ? 116 LEU C CD1 1 
ATOM 2518 C CD2 . LEU C 3 117 ? 115.899 117.109 133.662 1.00 63.49  ? 116 LEU C CD2 1 
ATOM 2519 N N   . ALA C 3 118 ? 117.167 113.605 129.669 1.00 64.75  ? 117 ALA C N   1 
ATOM 2520 C CA  . ALA C 3 118 ? 116.348 113.209 128.529 1.00 64.75  ? 117 ALA C CA  1 
ATOM 2521 C C   . ALA C 3 118 ? 116.691 111.804 128.048 1.00 64.75  ? 117 ALA C C   1 
ATOM 2522 O O   . ALA C 3 118 ? 116.193 111.368 127.006 1.00 64.75  ? 117 ALA C O   1 
ATOM 2523 C CB  . ALA C 3 118 ? 116.494 114.213 127.386 1.00 64.75  ? 117 ALA C CB  1 
ATOM 2524 N N   . SER C 3 119 ? 117.532 111.092 128.787 1.00 69.24  ? 118 SER C N   1 
ATOM 2525 C CA  . SER C 3 119 ? 117.939 109.744 128.437 1.00 69.24  ? 118 SER C CA  1 
ATOM 2526 C C   . SER C 3 119 ? 116.788 108.764 128.636 1.00 69.24  ? 118 SER C C   1 
ATOM 2527 O O   . SER C 3 119 ? 115.869 109.021 129.416 1.00 69.24  ? 118 SER C O   1 
ATOM 2528 C CB  . SER C 3 119 ? 119.139 109.330 129.282 1.00 69.24  ? 118 SER C CB  1 
ATOM 2529 O OG  . SER C 3 119 ? 119.299 107.924 129.305 1.00 69.24  ? 118 SER C OG  1 
ATOM 2530 N N   . PRO C 3 120 ? 116.809 107.632 127.927 1.00 76.89  ? 119 PRO C N   1 
ATOM 2531 C CA  . PRO C 3 120 ? 115.743 106.635 128.114 1.00 76.89  ? 119 PRO C CA  1 
ATOM 2532 C C   . PRO C 3 120 ? 115.599 106.150 129.546 1.00 76.89  ? 119 PRO C C   1 
ATOM 2533 O O   . PRO C 3 120 ? 114.503 105.732 129.936 1.00 76.89  ? 119 PRO C O   1 
ATOM 2534 C CB  . PRO C 3 120 ? 116.160 105.492 127.181 1.00 76.89  ? 119 PRO C CB  1 
ATOM 2535 C CG  . PRO C 3 120 ? 117.059 106.102 126.172 1.00 76.89  ? 119 PRO C CG  1 
ATOM 2536 C CD  . PRO C 3 120 ? 117.570 107.416 126.686 1.00 76.89  ? 119 PRO C CD  1 
ATOM 2537 N N   . LEU C 3 121 ? 116.672 106.174 130.338 1.00 73.85  ? 120 LEU C N   1 
ATOM 2538 C CA  . LEU C 3 121 ? 116.571 105.739 131.728 1.00 73.85  ? 120 LEU C CA  1 
ATOM 2539 C C   . LEU C 3 121 ? 115.726 106.704 132.553 1.00 73.85  ? 120 LEU C C   1 
ATOM 2540 O O   . LEU C 3 121 ? 114.805 106.288 133.267 1.00 73.85  ? 120 LEU C O   1 
ATOM 2541 C CB  . LEU C 3 121 ? 117.966 105.599 132.333 1.00 73.85  ? 120 LEU C CB  1 
ATOM 2542 C CG  . LEU C 3 121 ? 118.018 105.473 133.854 1.00 73.85  ? 120 LEU C CG  1 
ATOM 2543 C CD1 . LEU C 3 121 ? 117.381 104.170 134.301 1.00 73.85  ? 120 LEU C CD1 1 
ATOM 2544 C CD2 . LEU C 3 121 ? 119.450 105.570 134.352 1.00 73.85  ? 120 LEU C CD2 1 
ATOM 2545 N N   . LEU C 3 122 ? 116.018 108.002 132.462 1.00 71.54  ? 121 LEU C N   1 
ATOM 2546 C CA  . LEU C 3 122 ? 115.307 108.984 133.271 1.00 71.54  ? 121 LEU C CA  1 
ATOM 2547 C C   . LEU C 3 122 ? 113.884 109.232 132.792 1.00 71.54  ? 121 LEU C C   1 
ATOM 2548 O O   . LEU C 3 122 ? 112.998 109.447 133.627 1.00 71.54  ? 121 LEU C O   1 
ATOM 2549 C CB  . LEU C 3 122 ? 116.077 110.304 133.305 1.00 71.54  ? 121 LEU C CB  1 
ATOM 2550 C CG  . LEU C 3 122 ? 117.083 110.471 134.445 1.00 71.54  ? 121 LEU C CG  1 
ATOM 2551 C CD1 . LEU C 3 122 ? 116.363 110.503 135.778 1.00 71.54  ? 121 LEU C CD1 1 
ATOM 2552 C CD2 . LEU C 3 122 ? 118.130 109.371 134.434 1.00 71.54  ? 121 LEU C CD2 1 
ATOM 2553 N N   . ILE C 3 123 ? 113.637 109.208 131.478 1.00 73.34  ? 122 ILE C N   1 
ATOM 2554 C CA  . ILE C 3 123 ? 112.274 109.395 130.981 1.00 73.34  ? 122 ILE C CA  1 
ATOM 2555 C C   . ILE C 3 123 ? 111.354 108.261 131.386 1.00 73.34  ? 122 ILE C C   1 
ATOM 2556 O O   . ILE C 3 123 ? 110.133 108.386 131.241 1.00 73.34  ? 122 ILE C O   1 
ATOM 2557 C CB  . ILE C 3 123 ? 112.200 109.515 129.449 1.00 73.34  ? 122 ILE C CB  1 
ATOM 2558 C CG1 . ILE C 3 123 ? 112.632 108.206 128.795 1.00 73.34  ? 122 ILE C CG1 1 
ATOM 2559 C CG2 . ILE C 3 123 ? 113.071 110.651 128.962 1.00 73.34  ? 122 ILE C CG2 1 
ATOM 2560 C CD1 . ILE C 3 123 ? 112.365 108.154 127.309 1.00 73.34  ? 122 ILE C CD1 1 
ATOM 2561 N N   . ASP C 3 124 ? 111.903 107.150 131.869 1.00 78.87  ? 123 ASP C N   1 
ATOM 2562 C CA  . ASP C 3 124 ? 111.111 106.083 132.459 1.00 78.87  ? 123 ASP C CA  1 
ATOM 2563 C C   . ASP C 3 124 ? 111.106 106.118 133.976 1.00 78.87  ? 123 ASP C C   1 
ATOM 2564 O O   . ASP C 3 124 ? 110.088 105.791 134.584 1.00 78.87  ? 123 ASP C O   1 
ATOM 2565 C CB  . ASP C 3 124 ? 111.623 104.715 131.995 1.00 78.87  ? 123 ASP C CB  1 
ATOM 2566 C CG  . ASP C 3 124 ? 111.085 104.325 130.634 1.00 78.87  ? 123 ASP C CG  1 
ATOM 2567 O OD1 . ASP C 3 124 ? 110.150 104.997 130.151 1.00 78.87  ? 123 ASP C OD1 1 
ATOM 2568 O OD2 . ASP C 3 124 ? 111.598 103.350 130.047 1.00 78.87  ? 123 ASP C OD2 1 
ATOM 2569 N N   . ALA C 3 125 ? 112.216 106.518 134.599 1.00 76.77  ? 124 ALA C N   1 
ATOM 2570 C CA  . ALA C 3 125 ? 112.244 106.622 136.052 1.00 76.77  ? 124 ALA C CA  1 
ATOM 2571 C C   . ALA C 3 125 ? 111.333 107.733 136.558 1.00 76.77  ? 124 ALA C C   1 
ATOM 2572 O O   . ALA C 3 125 ? 110.811 107.639 137.674 1.00 76.77  ? 124 ALA C O   1 
ATOM 2573 C CB  . ALA C 3 125 ? 113.674 106.849 136.539 1.00 76.77  ? 124 ALA C CB  1 
ATOM 2574 N N   . ILE C 3 126 ? 111.129 108.782 135.768 1.00 74.53  ? 125 ILE C N   1 
ATOM 2575 C CA  . ILE C 3 126 ? 110.315 109.916 136.183 1.00 74.53  ? 125 ILE C CA  1 
ATOM 2576 C C   . ILE C 3 126 ? 108.875 109.785 135.706 1.00 74.53  ? 125 ILE C C   1 
ATOM 2577 O O   . ILE C 3 126 ? 107.944 110.077 136.455 1.00 74.53  ? 125 ILE C O   1 
ATOM 2578 C CB  . ILE C 3 126 ? 110.944 111.235 135.688 1.00 74.53  ? 125 ILE C CB  1 
ATOM 2579 C CG1 . ILE C 3 126 ? 112.294 111.465 136.360 1.00 74.53  ? 125 ILE C CG1 1 
ATOM 2580 C CG2 . ILE C 3 126 ? 110.019 112.402 135.961 1.00 74.53  ? 125 ILE C CG2 1 
ATOM 2581 C CD1 . ILE C 3 126 ? 113.225 112.332 135.556 1.00 74.53  ? 125 ILE C CD1 1 
ATOM 2582 N N   . ASP C 3 127 ? 108.668 109.363 134.460 1.00 77.91  ? 126 ASP C N   1 
ATOM 2583 C CA  . ASP C 3 127 ? 107.308 109.262 133.943 1.00 77.91  ? 126 ASP C CA  1 
ATOM 2584 C C   . ASP C 3 127 ? 106.578 108.053 134.514 1.00 77.91  ? 126 ASP C C   1 
ATOM 2585 O O   . ASP C 3 127 ? 105.391 108.139 134.845 1.00 77.91  ? 126 ASP C O   1 
ATOM 2586 C CB  . ASP C 3 127 ? 107.330 109.198 132.418 1.00 77.91  ? 126 ASP C CB  1 
ATOM 2587 C CG  . ASP C 3 127 ? 107.585 110.548 131.786 1.00 77.91  ? 126 ASP C CG  1 
ATOM 2588 O OD1 . ASP C 3 127 ? 108.240 111.391 132.431 1.00 77.91  ? 126 ASP C OD1 1 
ATOM 2589 O OD2 . ASP C 3 127 ? 107.136 110.767 130.642 1.00 77.91  ? 126 ASP C OD2 1 
ATOM 2590 N N   . GLN C 3 128 ? 107.266 106.918 134.638 1.00 81.67  ? 127 GLN C N   1 
ATOM 2591 C CA  . GLN C 3 128 ? 106.629 105.669 135.026 1.00 81.67  ? 127 GLN C CA  1 
ATOM 2592 C C   . GLN C 3 128 ? 106.875 105.275 136.476 1.00 81.67  ? 127 GLN C C   1 
ATOM 2593 O O   . GLN C 3 128 ? 106.227 104.341 136.959 1.00 81.67  ? 127 GLN C O   1 
ATOM 2594 C CB  . GLN C 3 128 ? 107.099 104.533 134.108 1.00 81.67  ? 127 GLN C CB  1 
ATOM 2595 C CG  . GLN C 3 128 ? 106.675 104.699 132.663 1.00 81.67  ? 127 GLN C CG  1 
ATOM 2596 C CD  . GLN C 3 128 ? 105.173 104.696 132.498 1.00 81.67  ? 127 GLN C CD  1 
ATOM 2597 O OE1 . GLN C 3 128 ? 104.568 105.725 132.203 1.00 81.67  ? 127 GLN C OE1 1 
ATOM 2598 N NE2 . GLN C 3 128 ? 104.560 103.534 132.690 1.00 81.67  ? 127 GLN C NE2 1 
ATOM 2599 N N   . LEU C 3 129 ? 107.790 105.949 137.174 1.00 74.71  ? 128 LEU C N   1 
ATOM 2600 C CA  . LEU C 3 129 ? 108.037 105.722 138.600 1.00 74.71  ? 128 LEU C CA  1 
ATOM 2601 C C   . LEU C 3 129 ? 108.451 104.280 138.887 1.00 74.71  ? 128 LEU C C   1 
ATOM 2602 O O   . LEU C 3 129 ? 107.973 103.660 139.838 1.00 74.71  ? 128 LEU C O   1 
ATOM 2603 C CB  . LEU C 3 129 ? 106.817 106.095 139.446 1.00 74.71  ? 128 LEU C CB  1 
ATOM 2604 C CG  . LEU C 3 129 ? 106.585 107.553 139.844 1.00 74.71  ? 128 LEU C CG  1 
ATOM 2605 C CD1 . LEU C 3 129 ? 107.710 108.065 140.726 1.00 74.71  ? 128 LEU C CD1 1 
ATOM 2606 C CD2 . LEU C 3 129 ? 106.401 108.434 138.633 1.00 74.71  ? 128 LEU C CD2 1 
ATOM 2607 N N   . ASN C 3 130 ? 109.346 103.736 138.067 1.00 79.21  ? 129 ASN C N   1 
ATOM 2608 C CA  . ASN C 3 130 ? 109.850 102.394 138.296 1.00 79.21  ? 129 ASN C CA  1 
ATOM 2609 C C   . ASN C 3 130 ? 111.348 102.438 138.563 1.00 79.21  ? 129 ASN C C   1 
ATOM 2610 O O   . ASN C 3 130 ? 112.088 103.080 137.806 1.00 79.21  ? 129 ASN C O   1 
ATOM 2611 C CB  . ASN C 3 130 ? 109.560 101.478 137.101 1.00 79.21  ? 129 ASN C CB  1 
ATOM 2612 C CG  . ASN C 3 130 ? 109.939 102.105 135.786 1.00 79.21  ? 129 ASN C CG  1 
ATOM 2613 O OD1 . ASN C 3 130 ? 109.622 103.262 135.528 1.00 79.21  ? 129 ASN C OD1 1 
ATOM 2614 N ND2 . ASN C 3 130 ? 110.619 101.344 134.939 1.00 79.21  ? 129 ASN C ND2 1 
ATOM 2615 N N   . PRO C 3 131 ? 111.828 101.782 139.617 1.00 78.00  ? 130 PRO C N   1 
ATOM 2616 C CA  . PRO C 3 131 ? 113.264 101.810 139.913 1.00 78.00  ? 130 PRO C CA  1 
ATOM 2617 C C   . PRO C 3 131 ? 114.083 101.187 138.795 1.00 78.00  ? 130 PRO C C   1 
ATOM 2618 O O   . PRO C 3 131 ? 113.631 100.282 138.090 1.00 78.00  ? 130 PRO C O   1 
ATOM 2619 C CB  . PRO C 3 131 ? 113.376 100.996 141.206 1.00 78.00  ? 130 PRO C CB  1 
ATOM 2620 C CG  . PRO C 3 131 ? 112.016 101.064 141.815 1.00 78.00  ? 130 PRO C CG  1 
ATOM 2621 C CD  . PRO C 3 131 ? 111.061 101.091 140.664 1.00 78.00  ? 130 PRO C CD  1 
ATOM 2622 N N   . ALA C 3 132 ? 115.302 101.690 138.636 1.00 78.47  ? 131 ALA C N   1 
ATOM 2623 C CA  . ALA C 3 132 ? 116.209 101.187 137.614 1.00 78.47  ? 131 ALA C CA  1 
ATOM 2624 C C   . ALA C 3 132 ? 116.701 99.785  137.958 1.00 78.47  ? 131 ALA C C   1 
ATOM 2625 O O   . ALA C 3 132 ? 116.502 99.301  139.072 1.00 78.47  ? 131 ALA C O   1 
ATOM 2626 C CB  . ALA C 3 132 ? 117.382 102.134 137.440 1.00 78.47  ? 131 ALA C CB  1 
ATOM 2627 N N   . ALA D 3 2   ? 112.585 99.270  133.931 1.00 86.06  ? 1   ALA c N   1 
ATOM 2628 C CA  . ALA D 3 2   ? 113.749 99.939  133.363 1.00 86.06  ? 1   ALA c CA  1 
ATOM 2629 C C   . ALA D 3 2   ? 115.032 99.233  133.777 1.00 86.06  ? 1   ALA c C   1 
ATOM 2630 O O   . ALA D 3 2   ? 115.668 99.607  134.761 1.00 86.06  ? 1   ALA c O   1 
ATOM 2631 C CB  . ALA D 3 2   ? 113.785 101.396 133.789 1.00 86.06  ? 1   ALA c CB  1 
ATOM 2632 N N   . LYS D 3 3   ? 115.405 98.206  133.020 1.00 86.24  ? 2   LYS c N   1 
ATOM 2633 C CA  . LYS D 3 3   ? 116.619 97.462  133.316 1.00 86.24  ? 2   LYS c CA  1 
ATOM 2634 C C   . LYS D 3 3   ? 117.844 98.324  133.038 1.00 86.24  ? 2   LYS c C   1 
ATOM 2635 O O   . LYS D 3 3   ? 117.883 99.080  132.063 1.00 86.24  ? 2   LYS c O   1 
ATOM 2636 C CB  . LYS D 3 3   ? 116.666 96.181  132.484 1.00 86.24  ? 2   LYS c CB  1 
ATOM 2637 C CG  . LYS D 3 3   ? 117.866 95.295  132.758 1.00 86.24  ? 2   LYS c CG  1 
ATOM 2638 C CD  . LYS D 3 3   ? 117.771 93.998  131.974 1.00 86.24  ? 2   LYS c CD  1 
ATOM 2639 C CE  . LYS D 3 3   ? 119.033 93.168  132.124 1.00 86.24  ? 2   LYS c CE  1 
ATOM 2640 N NZ  . LYS D 3 3   ? 119.214 92.691  133.523 1.00 86.24  ? 2   LYS c NZ  1 
ATOM 2641 N N   . LEU D 3 4   ? 118.843 98.216  133.908 1.00 81.64  ? 3   LEU c N   1 
ATOM 2642 C CA  . LEU D 3 4   ? 120.060 98.999  133.751 1.00 81.64  ? 3   LEU c CA  1 
ATOM 2643 C C   . LEU D 3 4   ? 120.816 98.569  132.501 1.00 81.64  ? 3   LEU c C   1 
ATOM 2644 O O   . LEU D 3 4   ? 120.872 97.383  132.164 1.00 81.64  ? 3   LEU c O   1 
ATOM 2645 C CB  . LEU D 3 4   ? 120.950 98.847  134.982 1.00 81.64  ? 3   LEU c CB  1 
ATOM 2646 C CG  . LEU D 3 4   ? 120.635 99.780  136.150 1.00 81.64  ? 3   LEU c CG  1 
ATOM 2647 C CD1 . LEU D 3 4   ? 121.648 99.601  137.265 1.00 81.64  ? 3   LEU c CD1 1 
ATOM 2648 C CD2 . LEU D 3 4   ? 120.604 101.221 135.680 1.00 81.64  ? 3   LEU c CD2 1 
ATOM 2649 N N   . GLU D 3 5   ? 121.398 99.544  131.809 1.00 81.65  ? 4   GLU c N   1 
ATOM 2650 C CA  . GLU D 3 5   ? 122.146 99.280  130.589 1.00 81.65  ? 4   GLU c CA  1 
ATOM 2651 C C   . GLU D 3 5   ? 123.125 100.423 130.370 1.00 81.65  ? 4   GLU c C   1 
ATOM 2652 O O   . GLU D 3 5   ? 123.023 101.480 130.995 1.00 81.65  ? 4   GLU c O   1 
ATOM 2653 C CB  . GLU D 3 5   ? 121.213 99.113  129.388 1.00 81.65  ? 4   GLU c CB  1 
ATOM 2654 C CG  . GLU D 3 5   ? 120.084 100.125 129.345 1.00 81.65  ? 4   GLU c CG  1 
ATOM 2655 C CD  . GLU D 3 5   ? 118.994 99.740  128.367 1.00 81.65  ? 4   GLU c CD  1 
ATOM 2656 O OE1 . GLU D 3 5   ? 118.884 98.539  128.040 1.00 81.65  ? 4   GLU c OE1 1 
ATOM 2657 O OE2 . GLU D 3 5   ? 118.246 100.637 127.925 1.00 81.65  ? 4   GLU c OE2 1 
ATOM 2658 N N   . THR D 3 6   ? 124.083 100.193 129.475 1.00 76.12  ? 5   THR c N   1 
ATOM 2659 C CA  . THR D 3 6   ? 125.078 101.212 129.171 1.00 76.12  ? 5   THR c CA  1 
ATOM 2660 C C   . THR D 3 6   ? 124.410 102.437 128.564 1.00 76.12  ? 5   THR c C   1 
ATOM 2661 O O   . THR D 3 6   ? 123.567 102.323 127.671 1.00 76.12  ? 5   THR c O   1 
ATOM 2662 C CB  . THR D 3 6   ? 126.133 100.662 128.213 1.00 76.12  ? 5   THR c CB  1 
ATOM 2663 O OG1 . THR D 3 6   ? 125.521 100.358 126.954 1.00 76.12  ? 5   THR c OG1 1 
ATOM 2664 C CG2 . THR D 3 6   ? 126.763 99.403  128.781 1.00 76.12  ? 5   THR c CG2 1 
ATOM 2665 N N   . VAL D 3 7   ? 124.792 103.613 129.052 1.00 71.95  ? 6   VAL c N   1 
ATOM 2666 C CA  . VAL D 3 7   ? 124.231 104.881 128.609 1.00 71.95  ? 6   VAL c CA  1 
ATOM 2667 C C   . VAL D 3 7   ? 125.341 105.692 127.961 1.00 71.95  ? 6   VAL c C   1 
ATOM 2668 O O   . VAL D 3 7   ? 126.382 105.937 128.582 1.00 71.95  ? 6   VAL c O   1 
ATOM 2669 C CB  . VAL D 3 7   ? 123.597 105.658 129.777 1.00 71.95  ? 6   VAL c CB  1 
ATOM 2670 C CG1 . VAL D 3 7   ? 122.884 106.891 129.265 1.00 71.95  ? 6   VAL c CG1 1 
ATOM 2671 C CG2 . VAL D 3 7   ? 122.640 104.768 130.546 1.00 71.95  ? 6   VAL c CG2 1 
ATOM 2672 N N   . THR D 3 8   ? 125.120 106.107 126.719 1.00 73.62  ? 7   THR c N   1 
ATOM 2673 C CA  . THR D 3 8   ? 126.084 106.904 125.966 1.00 73.62  ? 7   THR c CA  1 
ATOM 2674 C C   . THR D 3 8   ? 125.488 108.292 125.771 1.00 73.62  ? 7   THR c C   1 
ATOM 2675 O O   . THR D 3 8   ? 124.667 108.503 124.876 1.00 73.62  ? 7   THR c O   1 
ATOM 2676 C CB  . THR D 3 8   ? 126.409 106.257 124.625 1.00 73.62  ? 7   THR c CB  1 
ATOM 2677 O OG1 . THR D 3 8   ? 125.279 106.381 123.756 1.00 73.62  ? 7   THR c OG1 1 
ATOM 2678 C CG2 . THR D 3 8   ? 126.724 104.788 124.804 1.00 73.62  ? 7   THR c CG2 1 
ATOM 2679 N N   . LEU D 3 9   ? 125.908 109.236 126.606 1.00 71.12  ? 8   LEU c N   1 
ATOM 2680 C CA  . LEU D 3 9   ? 125.445 110.606 126.475 1.00 71.12  ? 8   LEU c CA  1 
ATOM 2681 C C   . LEU D 3 9   ? 126.256 111.327 125.411 1.00 71.12  ? 8   LEU c C   1 
ATOM 2682 O O   . LEU D 3 9   ? 127.492 111.322 125.440 1.00 71.12  ? 8   LEU c O   1 
ATOM 2683 C CB  . LEU D 3 9   ? 125.560 111.345 127.806 1.00 71.12  ? 8   LEU c CB  1 
ATOM 2684 C CG  . LEU D 3 9   ? 124.935 110.666 129.018 1.00 71.12  ? 8   LEU c CG  1 
ATOM 2685 C CD1 . LEU D 3 9   ? 125.204 111.475 130.270 1.00 71.12  ? 8   LEU c CD1 1 
ATOM 2686 C CD2 . LEU D 3 9   ? 123.449 110.495 128.801 1.00 71.12  ? 8   LEU c CD2 1 
ATOM 2687 N N   . GLY D 3 10  ? 125.549 111.947 124.468 1.00 71.50  ? 9   GLY c N   1 
ATOM 2688 C CA  . GLY D 3 10  ? 126.182 112.687 123.396 1.00 71.50  ? 9   GLY c CA  1 
ATOM 2689 C C   . GLY D 3 10  ? 125.966 114.179 123.514 1.00 71.50  ? 9   GLY c C   1 
ATOM 2690 O O   . GLY D 3 10  ? 125.133 114.627 124.306 1.00 71.50  ? 9   GLY c O   1 
ATOM 2691 N N   . ASN D 3 11  ? 126.721 114.955 122.741 1.00 71.11  ? 10  ASN c N   1 
ATOM 2692 C CA  . ASN D 3 11  ? 126.648 116.413 122.701 1.00 71.11  ? 10  ASN c CA  1 
ATOM 2693 C C   . ASN D 3 11  ? 127.005 117.060 124.033 1.00 71.11  ? 10  ASN c C   1 
ATOM 2694 O O   . ASN D 3 11  ? 126.717 118.243 124.239 1.00 71.11  ? 10  ASN c O   1 
ATOM 2695 C CB  . ASN D 3 11  ? 125.265 116.893 122.245 1.00 71.11  ? 10  ASN c CB  1 
ATOM 2696 C CG  . ASN D 3 11  ? 125.304 118.264 121.608 1.00 71.11  ? 10  ASN c CG  1 
ATOM 2697 O OD1 . ASN D 3 11  ? 126.374 118.823 121.380 1.00 71.11  ? 10  ASN c OD1 1 
ATOM 2698 N ND2 . ASN D 3 11  ? 124.133 118.815 121.318 1.00 71.11  ? 10  ASN c ND2 1 
ATOM 2699 N N   . ILE D 3 12  ? 127.628 116.316 124.945 1.00 69.85  ? 11  ILE c N   1 
ATOM 2700 C CA  . ILE D 3 12  ? 128.020 116.878 126.228 1.00 69.85  ? 11  ILE c CA  1 
ATOM 2701 C C   . ILE D 3 12  ? 129.273 117.729 126.055 1.00 69.85  ? 11  ILE c C   1 
ATOM 2702 O O   . ILE D 3 12  ? 130.075 117.521 125.136 1.00 69.85  ? 11  ILE c O   1 
ATOM 2703 C CB  . ILE D 3 12  ? 128.241 115.753 127.253 1.00 69.85  ? 11  ILE c CB  1 
ATOM 2704 C CG1 . ILE D 3 12  ? 128.400 116.321 128.658 1.00 69.85  ? 11  ILE c CG1 1 
ATOM 2705 C CG2 . ILE D 3 12  ? 129.457 114.934 126.894 1.00 69.85  ? 11  ILE c CG2 1 
ATOM 2706 C CD1 . ILE D 3 12  ? 128.304 115.289 129.730 1.00 69.85  ? 11  ILE c CD1 1 
ATOM 2707 N N   . GLY D 3 13  ? 129.440 118.704 126.937 1.00 71.24  ? 12  GLY c N   1 
ATOM 2708 C CA  . GLY D 3 13  ? 130.612 119.554 126.946 1.00 71.24  ? 12  GLY c CA  1 
ATOM 2709 C C   . GLY D 3 13  ? 130.263 121.008 126.685 1.00 71.24  ? 12  GLY c C   1 
ATOM 2710 O O   . GLY D 3 13  ? 129.156 121.356 126.279 1.00 71.24  ? 12  GLY c O   1 
ATOM 2711 N N   . LYS D 3 14  ? 131.255 121.863 126.944 1.00 79.66  ? 13  LYS c N   1 
ATOM 2712 C CA  . LYS D 3 14  ? 131.081 123.290 126.695 1.00 79.66  ? 13  LYS c CA  1 
ATOM 2713 C C   . LYS D 3 14  ? 130.870 123.569 125.213 1.00 79.66  ? 13  LYS c C   1 
ATOM 2714 O O   . LYS D 3 14  ? 130.002 124.363 124.836 1.00 79.66  ? 13  LYS c O   1 
ATOM 2715 C CB  . LYS D 3 14  ? 132.287 124.069 127.217 1.00 79.66  ? 13  LYS c CB  1 
ATOM 2716 C CG  . LYS D 3 14  ? 132.237 125.549 126.885 1.00 79.66  ? 13  LYS c CG  1 
ATOM 2717 C CD  . LYS D 3 14  ? 133.432 126.292 127.449 1.00 79.66  ? 13  LYS c CD  1 
ATOM 2718 C CE  . LYS D 3 14  ? 133.281 126.514 128.940 1.00 79.66  ? 13  LYS c CE  1 
ATOM 2719 N NZ  . LYS D 3 14  ? 132.143 127.427 129.232 1.00 79.66  ? 13  LYS c NZ  1 
ATOM 2720 N N   . ASP D 3 15  ? 131.656 122.922 124.358 1.00 78.97  ? 14  ASP c N   1 
ATOM 2721 C CA  . ASP D 3 15  ? 131.563 123.127 122.920 1.00 78.97  ? 14  ASP c CA  1 
ATOM 2722 C C   . ASP D 3 15  ? 130.566 122.193 122.251 1.00 78.97  ? 14  ASP c C   1 
ATOM 2723 O O   . ASP D 3 15  ? 130.369 122.290 121.036 1.00 78.97  ? 14  ASP c O   1 
ATOM 2724 C CB  . ASP D 3 15  ? 132.941 122.957 122.274 1.00 78.97  ? 14  ASP c CB  1 
ATOM 2725 C CG  . ASP D 3 15  ? 133.667 121.727 122.769 1.00 78.97  ? 14  ASP c CG  1 
ATOM 2726 O OD1 . ASP D 3 15  ? 133.001 120.704 123.024 1.00 78.97  ? 14  ASP c OD1 1 
ATOM 2727 O OD2 . ASP D 3 15  ? 134.906 121.784 122.908 1.00 78.97  ? 14  ASP c OD2 1 
ATOM 2728 N N   . GLY D 3 16  ? 129.932 121.304 123.007 1.00 75.18  ? 15  GLY c N   1 
ATOM 2729 C CA  . GLY D 3 16  ? 128.992 120.366 122.415 1.00 75.18  ? 15  GLY c CA  1 
ATOM 2730 C C   . GLY D 3 16  ? 129.641 119.387 121.463 1.00 75.18  ? 15  GLY c C   1 
ATOM 2731 O O   . GLY D 3 16  ? 129.036 119.011 120.452 1.00 75.18  ? 15  GLY c O   1 
ATOM 2732 N N   . LYS D 3 17  ? 130.862 118.964 121.765 1.00 73.74  ? 16  LYS c N   1 
ATOM 2733 C CA  . LYS D 3 17  ? 131.598 118.040 120.918 1.00 73.74  ? 16  LYS c CA  1 
ATOM 2734 C C   . LYS D 3 17  ? 131.941 116.727 121.600 1.00 73.74  ? 16  LYS c C   1 
ATOM 2735 O O   . LYS D 3 17  ? 132.024 115.703 120.922 1.00 73.74  ? 16  LYS c O   1 
ATOM 2736 C CB  . LYS D 3 17  ? 132.896 118.694 120.424 1.00 73.74  ? 16  LYS c CB  1 
ATOM 2737 C CG  . LYS D 3 17  ? 133.320 118.256 119.041 1.00 73.74  ? 16  LYS c CG  1 
ATOM 2738 C CD  . LYS D 3 17  ? 134.552 119.012 118.585 1.00 73.74  ? 16  LYS c CD  1 
ATOM 2739 C CE  . LYS D 3 17  ? 134.317 120.510 118.605 1.00 73.74  ? 16  LYS c CE  1 
ATOM 2740 N NZ  . LYS D 3 17  ? 133.318 120.921 117.585 1.00 73.74  ? 16  LYS c NZ  1 
ATOM 2741 N N   . GLN D 3 18  ? 132.133 116.726 122.914 1.00 73.21  ? 17  GLN c N   1 
ATOM 2742 C CA  . GLN D 3 18  ? 132.483 115.511 123.626 1.00 73.21  ? 17  GLN c CA  1 
ATOM 2743 C C   . GLN D 3 18  ? 131.260 114.621 123.810 1.00 73.21  ? 17  GLN c C   1 
ATOM 2744 O O   . GLN D 3 18  ? 130.115 115.037 123.628 1.00 73.21  ? 17  GLN c O   1 
ATOM 2745 C CB  . GLN D 3 18  ? 133.096 115.839 124.985 1.00 73.21  ? 17  GLN c CB  1 
ATOM 2746 C CG  . GLN D 3 18  ? 134.056 117.007 124.972 1.00 73.21  ? 17  GLN c CG  1 
ATOM 2747 C CD  . GLN D 3 18  ? 134.538 117.366 126.358 1.00 73.21  ? 17  GLN c CD  1 
ATOM 2748 O OE1 . GLN D 3 18  ? 135.293 116.618 126.976 1.00 73.21  ? 17  GLN c OE1 1 
ATOM 2749 N NE2 . GLN D 3 18  ? 134.104 118.515 126.857 1.00 73.21  ? 17  GLN c NE2 1 
ATOM 2750 N N   . THR D 3 19  ? 131.523 113.372 124.178 1.00 76.64  ? 18  THR c N   1 
ATOM 2751 C CA  . THR D 3 19  ? 130.479 112.420 124.526 1.00 76.64  ? 18  THR c CA  1 
ATOM 2752 C C   . THR D 3 19  ? 131.087 111.378 125.449 1.00 76.64  ? 18  THR c C   1 
ATOM 2753 O O   . THR D 3 19  ? 132.283 111.087 125.367 1.00 76.64  ? 18  THR c O   1 
ATOM 2754 C CB  . THR D 3 19  ? 129.867 111.763 123.285 1.00 76.64  ? 18  THR c CB  1 
ATOM 2755 O OG1 . THR D 3 19  ? 128.743 110.966 123.671 1.00 76.64  ? 18  THR c OG1 1 
ATOM 2756 C CG2 . THR D 3 19  ? 130.873 110.890 122.592 1.00 76.64  ? 18  THR c CG2 1 
ATOM 2757 N N   . LEU D 3 20  ? 130.266 110.837 126.344 1.00 71.18  ? 19  LEU c N   1 
ATOM 2758 C CA  . LEU D 3 20  ? 130.780 109.887 127.320 1.00 71.18  ? 19  LEU c CA  1 
ATOM 2759 C C   . LEU D 3 20  ? 129.902 108.649 127.387 1.00 71.18  ? 19  LEU c C   1 
ATOM 2760 O O   . LEU D 3 20  ? 128.672 108.739 127.361 1.00 71.18  ? 19  LEU c O   1 
ATOM 2761 C CB  . LEU D 3 20  ? 130.899 110.499 128.725 1.00 71.18  ? 19  LEU c CB  1 
ATOM 2762 C CG  . LEU D 3 20  ? 129.645 110.744 129.560 1.00 71.18  ? 19  LEU c CG  1 
ATOM 2763 C CD1 . LEU D 3 20  ? 130.020 110.985 131.010 1.00 71.18  ? 19  LEU c CD1 1 
ATOM 2764 C CD2 . LEU D 3 20  ? 128.861 111.906 129.016 1.00 71.18  ? 19  LEU c CD2 1 
ATOM 2765 N N   . VAL D 3 21  ? 130.552 107.495 127.490 1.00 69.32  ? 20  VAL c N   1 
ATOM 2766 C CA  . VAL D 3 21  ? 129.882 106.225 127.724 1.00 69.32  ? 20  VAL c CA  1 
ATOM 2767 C C   . VAL D 3 21  ? 130.067 105.854 129.187 1.00 69.32  ? 20  VAL c C   1 
ATOM 2768 O O   . VAL D 3 21  ? 131.180 105.924 129.723 1.00 69.32  ? 20  VAL c O   1 
ATOM 2769 C CB  . VAL D 3 21  ? 130.409 105.129 126.778 1.00 69.32  ? 20  VAL c CB  1 
ATOM 2770 C CG1 . VAL D 3 21  ? 131.827 104.712 127.130 1.00 69.32  ? 20  VAL c CG1 1 
ATOM 2771 C CG2 . VAL D 3 21  ? 129.498 103.919 126.823 1.00 69.32  ? 20  VAL c CG2 1 
ATOM 2772 N N   . LEU D 3 22  ? 128.967 105.526 129.855 1.00 69.06  ? 21  LEU c N   1 
ATOM 2773 C CA  . LEU D 3 22  ? 128.992 105.138 131.255 1.00 69.06  ? 21  LEU c CA  1 
ATOM 2774 C C   . LEU D 3 22  ? 128.126 103.904 131.439 1.00 69.06  ? 21  LEU c C   1 
ATOM 2775 O O   . LEU D 3 22  ? 127.032 103.818 130.873 1.00 69.06  ? 21  LEU c O   1 
ATOM 2776 C CB  . LEU D 3 22  ? 128.544 106.304 132.150 1.00 69.06  ? 21  LEU c CB  1 
ATOM 2777 C CG  . LEU D 3 22  ? 127.162 106.943 132.000 1.00 69.06  ? 21  LEU c CG  1 
ATOM 2778 C CD1 . LEU D 3 22  ? 126.088 106.193 132.749 1.00 69.06  ? 21  LEU c CD1 1 
ATOM 2779 C CD2 . LEU D 3 22  ? 127.217 108.387 132.465 1.00 69.06  ? 21  LEU c CD2 1 
ATOM 2780 N N   . ASN D 3 23  ? 128.623 102.952 132.215 1.00 70.40  ? 22  ASN c N   1 
ATOM 2781 C CA  . ASN D 3 23  ? 128.024 101.641 132.375 1.00 70.40  ? 22  ASN c CA  1 
ATOM 2782 C C   . ASN D 3 23  ? 127.583 101.407 133.816 1.00 70.40  ? 22  ASN c C   1 
ATOM 2783 O O   . ASN D 3 23  ? 128.100 102.039 134.746 1.00 70.40  ? 22  ASN c O   1 
ATOM 2784 C CB  . ASN D 3 23  ? 129.008 100.552 131.917 1.00 70.40  ? 22  ASN c CB  1 
ATOM 2785 C CG  . ASN D 3 23  ? 130.297 100.534 132.721 1.00 70.40  ? 22  ASN c CG  1 
ATOM 2786 O OD1 . ASN D 3 23  ? 130.449 101.253 133.705 1.00 70.40  ? 22  ASN c OD1 1 
ATOM 2787 N ND2 . ASN D 3 23  ? 131.240 99.706  132.292 1.00 70.40  ? 22  ASN c ND2 1 
ATOM 2788 N N   . PRO D 3 24  ? 126.601 100.534 134.034 1.00 67.53  ? 23  PRO c N   1 
ATOM 2789 C CA  . PRO D 3 24  ? 126.071 100.340 135.385 1.00 67.53  ? 23  PRO c CA  1 
ATOM 2790 C C   . PRO D 3 24  ? 127.032 99.570  136.274 1.00 67.53  ? 23  PRO c C   1 
ATOM 2791 O O   . PRO D 3 24  ? 127.907 98.837  135.811 1.00 67.53  ? 23  PRO c O   1 
ATOM 2792 C CB  . PRO D 3 24  ? 124.789 99.539  135.145 1.00 67.53  ? 23  PRO c CB  1 
ATOM 2793 C CG  . PRO D 3 24  ? 125.064 98.801  133.891 1.00 67.53  ? 23  PRO c CG  1 
ATOM 2794 C CD  . PRO D 3 24  ? 125.844 99.756  133.040 1.00 67.53  ? 23  PRO c CD  1 
ATOM 2795 N N   . ARG D 3 25  ? 126.852 99.750  137.580 1.00 69.00  ? 24  ARG c N   1 
ATOM 2796 C CA  . ARG D 3 25  ? 127.582 98.999  138.593 1.00 69.00  ? 24  ARG c CA  1 
ATOM 2797 C C   . ARG D 3 25  ? 126.649 98.524  139.694 1.00 69.00  ? 24  ARG c C   1 
ATOM 2798 O O   . ARG D 3 25  ? 126.952 98.637  140.885 1.00 69.00  ? 24  ARG c O   1 
ATOM 2799 C CB  . ARG D 3 25  ? 128.729 99.815  139.182 1.00 69.00  ? 24  ARG c CB  1 
ATOM 2800 C CG  . ARG D 3 25  ? 129.732 100.310 138.167 1.00 69.00  ? 24  ARG c CG  1 
ATOM 2801 C CD  . ARG D 3 25  ? 131.118 100.322 138.775 1.00 69.00  ? 24  ARG c CD  1 
ATOM 2802 N NE  . ARG D 3 25  ? 132.161 100.296 137.759 1.00 69.00  ? 24  ARG c NE  1 
ATOM 2803 C CZ  . ARG D 3 25  ? 133.184 101.136 137.722 1.00 69.00  ? 24  ARG c CZ  1 
ATOM 2804 N NH1 . ARG D 3 25  ? 133.352 102.058 138.654 1.00 69.00  ? 24  ARG c NH1 1 
ATOM 2805 N NH2 . ARG D 3 25  ? 134.066 101.043 136.731 1.00 69.00  ? 24  ARG c NH2 1 
ATOM 2806 N N   . GLY D 3 26  ? 125.493 97.991  139.314 1.00 73.12  ? 25  GLY c N   1 
ATOM 2807 C CA  . GLY D 3 26  ? 124.615 97.327  140.252 1.00 73.12  ? 25  GLY c CA  1 
ATOM 2808 C C   . GLY D 3 26  ? 123.819 98.290  141.110 1.00 73.12  ? 25  GLY c C   1 
ATOM 2809 O O   . GLY D 3 26  ? 123.943 99.512  141.028 1.00 73.12  ? 25  GLY c O   1 
ATOM 2810 N N   . VAL D 3 27  ? 122.982 97.709  141.965 1.00 74.68  ? 26  VAL c N   1 
ATOM 2811 C CA  . VAL D 3 27  ? 122.103 98.454  142.855 1.00 74.68  ? 26  VAL c CA  1 
ATOM 2812 C C   . VAL D 3 27  ? 122.446 98.095  144.294 1.00 74.68  ? 26  VAL c C   1 
ATOM 2813 O O   . VAL D 3 27  ? 122.715 96.930  144.608 1.00 74.68  ? 26  VAL c O   1 
ATOM 2814 C CB  . VAL D 3 27  ? 120.620 98.173  142.541 1.00 74.68  ? 26  VAL c CB  1 
ATOM 2815 C CG1 . VAL D 3 27  ? 120.308 96.694  142.686 1.00 74.68  ? 26  VAL c CG1 1 
ATOM 2816 C CG2 . VAL D 3 27  ? 119.715 99.000  143.437 1.00 74.68  ? 26  VAL c CG2 1 
ATOM 2817 N N   . ASN D 3 28  ? 122.463 99.101  145.160 1.00 77.01  ? 27  ASN c N   1 
ATOM 2818 C CA  . ASN D 3 28  ? 122.761 98.877  146.568 1.00 77.01  ? 27  ASN c CA  1 
ATOM 2819 C C   . ASN D 3 28  ? 121.537 98.297  147.266 1.00 77.01  ? 27  ASN c C   1 
ATOM 2820 O O   . ASN D 3 28  ? 120.488 98.949  147.296 1.00 77.01  ? 27  ASN c O   1 
ATOM 2821 C CB  . ASN D 3 28  ? 123.180 100.179 147.235 1.00 77.01  ? 27  ASN c CB  1 
ATOM 2822 C CG  . ASN D 3 28  ? 123.287 100.057 148.741 1.00 77.01  ? 27  ASN c CG  1 
ATOM 2823 O OD1 . ASN D 3 28  ? 123.674 99.014  149.266 1.00 77.01  ? 27  ASN c OD1 1 
ATOM 2824 N ND2 . ASN D 3 28  ? 122.941 101.127 149.445 1.00 77.01  ? 27  ASN c ND2 1 
ATOM 2825 N N   . PRO D 3 29  ? 121.621 97.092  147.833 1.00 77.80  ? 28  PRO c N   1 
ATOM 2826 C CA  . PRO D 3 29  ? 120.444 96.506  148.493 1.00 77.80  ? 28  PRO c CA  1 
ATOM 2827 C C   . PRO D 3 29  ? 119.979 97.275  149.716 1.00 77.80  ? 28  PRO c C   1 
ATOM 2828 O O   . PRO D 3 29  ? 118.809 97.149  150.096 1.00 77.80  ? 28  PRO c O   1 
ATOM 2829 C CB  . PRO D 3 29  ? 120.917 95.095  148.872 1.00 77.80  ? 28  PRO c CB  1 
ATOM 2830 C CG  . PRO D 3 29  ? 122.129 94.846  148.026 1.00 77.80  ? 28  PRO c CG  1 
ATOM 2831 C CD  . PRO D 3 29  ? 122.773 96.178  147.843 1.00 77.80  ? 28  PRO c CD  1 
ATOM 2832 N N   . THR D 3 30  ? 120.856 98.057  150.349 1.00 79.24  ? 29  THR c N   1 
ATOM 2833 C CA  . THR D 3 30  ? 120.482 98.742  151.582 1.00 79.24  ? 29  THR c CA  1 
ATOM 2834 C C   . THR D 3 30  ? 119.384 99.772  151.341 1.00 79.24  ? 29  THR c C   1 
ATOM 2835 O O   . THR D 3 30  ? 118.424 99.855  152.116 1.00 79.24  ? 29  THR c O   1 
ATOM 2836 C CB  . THR D 3 30  ? 121.711 99.404  152.205 1.00 79.24  ? 29  THR c CB  1 
ATOM 2837 O OG1 . THR D 3 30  ? 122.621 98.395  152.659 1.00 79.24  ? 29  THR c OG1 1 
ATOM 2838 C CG2 . THR D 3 30  ? 121.310 100.280 153.382 1.00 79.24  ? 29  THR c CG2 1 
ATOM 2839 N N   . ASN D 3 31  ? 119.497 100.553 150.266 1.00 77.38  ? 30  ASN c N   1 
ATOM 2840 C CA  . ASN D 3 31  ? 118.539 101.622 150.014 1.00 77.38  ? 30  ASN c CA  1 
ATOM 2841 C C   . ASN D 3 31  ? 118.093 101.708 148.558 1.00 77.38  ? 30  ASN c C   1 
ATOM 2842 O O   . ASN D 3 31  ? 117.406 102.671 148.198 1.00 77.38  ? 30  ASN c O   1 
ATOM 2843 C CB  . ASN D 3 31  ? 119.120 102.967 150.464 1.00 77.38  ? 30  ASN c CB  1 
ATOM 2844 C CG  . ASN D 3 31  ? 120.523 103.198 149.945 1.00 77.38  ? 30  ASN c CG  1 
ATOM 2845 O OD1 . ASN D 3 31  ? 120.863 102.791 148.836 1.00 77.38  ? 30  ASN c OD1 1 
ATOM 2846 N ND2 . ASN D 3 31  ? 121.349 103.855 150.749 1.00 77.38  ? 30  ASN c ND2 1 
ATOM 2847 N N   . GLY D 3 32  ? 118.454 100.744 147.717 1.00 76.77  ? 31  GLY c N   1 
ATOM 2848 C CA  . GLY D 3 32  ? 117.955 100.715 146.351 1.00 76.77  ? 31  GLY c CA  1 
ATOM 2849 C C   . GLY D 3 32  ? 118.371 101.891 145.496 1.00 76.77  ? 31  GLY c C   1 
ATOM 2850 O O   . GLY D 3 32  ? 117.539 102.455 144.775 1.00 76.77  ? 31  GLY c O   1 
ATOM 2851 N N   . VAL D 3 33  ? 119.641 102.274 145.554 1.00 68.77  ? 32  VAL c N   1 
ATOM 2852 C CA  . VAL D 3 33  ? 120.165 103.390 144.777 1.00 68.77  ? 32  VAL c CA  1 
ATOM 2853 C C   . VAL D 3 33  ? 120.992 102.819 143.633 1.00 68.77  ? 32  VAL c C   1 
ATOM 2854 O O   . VAL D 3 33  ? 122.106 102.328 143.845 1.00 68.77  ? 32  VAL c O   1 
ATOM 2855 C CB  . VAL D 3 33  ? 120.998 104.340 145.645 1.00 68.77  ? 32  VAL c CB  1 
ATOM 2856 C CG1 . VAL D 3 33  ? 121.651 105.398 144.784 1.00 68.77  ? 32  VAL c CG1 1 
ATOM 2857 C CG2 . VAL D 3 33  ? 120.125 104.987 146.702 1.00 68.77  ? 32  VAL c CG2 1 
ATOM 2858 N N   . ALA D 3 34  ? 120.452 102.880 142.420 1.00 66.76  ? 33  ALA c N   1 
ATOM 2859 C CA  . ALA D 3 34  ? 121.181 102.404 141.253 1.00 66.76  ? 33  ALA c CA  1 
ATOM 2860 C C   . ALA D 3 34  ? 122.357 103.321 140.955 1.00 66.76  ? 33  ALA c C   1 
ATOM 2861 O O   . ALA D 3 34  ? 122.257 104.544 141.080 1.00 66.76  ? 33  ALA c O   1 
ATOM 2862 C CB  . ALA D 3 34  ? 120.255 102.326 140.042 1.00 66.76  ? 33  ALA c CB  1 
ATOM 2863 N N   . SER D 3 35  ? 123.475 102.726 140.550 1.00 66.61  ? 34  SER c N   1 
ATOM 2864 C CA  . SER D 3 35  ? 124.712 103.453 140.313 1.00 66.61  ? 34  SER c CA  1 
ATOM 2865 C C   . SER D 3 35  ? 125.227 103.174 138.909 1.00 66.61  ? 34  SER c C   1 
ATOM 2866 O O   . SER D 3 35  ? 125.107 102.055 138.404 1.00 66.61  ? 34  SER c O   1 
ATOM 2867 C CB  . SER D 3 35  ? 125.784 103.069 141.337 1.00 66.61  ? 34  SER c CB  1 
ATOM 2868 O OG  . SER D 3 35  ? 125.355 103.343 142.658 1.00 66.61  ? 34  SER c OG  1 
ATOM 2869 N N   . LEU D 3 36  ? 125.795 104.201 138.284 1.00 65.48  ? 35  LEU c N   1 
ATOM 2870 C CA  . LEU D 3 36  ? 126.450 104.080 136.993 1.00 65.48  ? 35  LEU c CA  1 
ATOM 2871 C C   . LEU D 3 36  ? 127.741 104.879 137.044 1.00 65.48  ? 35  LEU c C   1 
ATOM 2872 O O   . LEU D 3 36  ? 127.851 105.846 137.801 1.00 65.48  ? 35  LEU c O   1 
ATOM 2873 C CB  . LEU D 3 36  ? 125.559 104.581 135.854 1.00 65.48  ? 35  LEU c CB  1 
ATOM 2874 C CG  . LEU D 3 36  ? 124.207 103.895 135.670 1.00 65.48  ? 35  LEU c CG  1 
ATOM 2875 C CD1 . LEU D 3 36  ? 123.127 104.625 136.440 1.00 65.48  ? 35  LEU c CD1 1 
ATOM 2876 C CD2 . LEU D 3 36  ? 123.845 103.810 134.203 1.00 65.48  ? 35  LEU c CD2 1 
ATOM 2877 N N   . SER D 3 37  ? 128.721 104.477 136.241 1.00 69.00  ? 36  SER c N   1 
ATOM 2878 C CA  . SER D 3 37  ? 130.009 105.154 136.296 1.00 69.00  ? 36  SER c CA  1 
ATOM 2879 C C   . SER D 3 37  ? 130.753 104.959 134.987 1.00 69.00  ? 36  SER c C   1 
ATOM 2880 O O   . SER D 3 37  ? 130.411 104.097 134.177 1.00 69.00  ? 36  SER c O   1 
ATOM 2881 C CB  . SER D 3 37  ? 130.851 104.647 137.468 1.00 69.00  ? 36  SER c CB  1 
ATOM 2882 O OG  . SER D 3 37  ? 131.199 103.291 137.279 1.00 69.00  ? 36  SER c OG  1 
ATOM 2883 N N   . GLN D 3 38  ? 131.784 105.776 134.798 1.00 72.17  ? 37  GLN c N   1 
ATOM 2884 C CA  . GLN D 3 38  ? 132.620 105.723 133.609 1.00 72.17  ? 37  GLN c CA  1 
ATOM 2885 C C   . GLN D 3 38  ? 133.843 104.855 133.866 1.00 72.17  ? 37  GLN c C   1 
ATOM 2886 O O   . GLN D 3 38  ? 134.452 104.921 134.937 1.00 72.17  ? 37  GLN c O   1 
ATOM 2887 C CB  . GLN D 3 38  ? 133.057 107.129 133.200 1.00 72.17  ? 37  GLN c CB  1 
ATOM 2888 C CG  . GLN D 3 38  ? 134.079 107.162 132.083 1.00 72.17  ? 37  GLN c CG  1 
ATOM 2889 C CD  . GLN D 3 38  ? 134.448 108.570 131.674 1.00 72.17  ? 37  GLN c CD  1 
ATOM 2890 O OE1 . GLN D 3 38  ? 134.598 109.453 132.516 1.00 72.17  ? 37  GLN c OE1 1 
ATOM 2891 N NE2 . GLN D 3 38  ? 134.603 108.788 130.374 1.00 72.17  ? 37  GLN c NE2 1 
ATOM 2892 N N   . ALA D 3 39  ? 134.201 104.040 132.876 1.00 78.05  ? 38  ALA c N   1 
ATOM 2893 C CA  . ALA D 3 39  ? 135.359 103.154 132.981 1.00 78.05  ? 38  ALA c CA  1 
ATOM 2894 C C   . ALA D 3 39  ? 136.622 103.989 132.820 1.00 78.05  ? 38  ALA c C   1 
ATOM 2895 O O   . ALA D 3 39  ? 137.168 104.131 131.725 1.00 78.05  ? 38  ALA c O   1 
ATOM 2896 C CB  . ALA D 3 39  ? 135.284 102.046 131.939 1.00 78.05  ? 38  ALA c CB  1 
ATOM 2897 N N   . GLY D 3 40  ? 137.095 104.549 133.930 1.00 84.39  ? 39  GLY c N   1 
ATOM 2898 C CA  . GLY D 3 40  ? 138.264 105.401 133.945 1.00 84.39  ? 39  GLY c CA  1 
ATOM 2899 C C   . GLY D 3 40  ? 139.556 104.738 134.368 1.00 84.39  ? 39  GLY c C   1 
ATOM 2900 O O   . GLY D 3 40  ? 140.533 105.448 134.637 1.00 84.39  ? 39  GLY c O   1 
ATOM 2901 N N   . ALA D 3 41  ? 139.582 103.407 134.475 1.00 84.74  ? 40  ALA c N   1 
ATOM 2902 C CA  . ALA D 3 41  ? 140.782 102.628 134.774 1.00 84.74  ? 40  ALA c CA  1 
ATOM 2903 C C   . ALA D 3 41  ? 141.293 102.863 136.193 1.00 84.74  ? 40  ALA c C   1 
ATOM 2904 O O   . ALA D 3 41  ? 142.252 102.215 136.621 1.00 84.74  ? 40  ALA c O   1 
ATOM 2905 C CB  . ALA D 3 41  ? 141.889 102.923 133.758 1.00 84.74  ? 40  ALA c CB  1 
ATOM 2906 N N   . VAL D 3 42  ? 140.664 103.774 136.929 1.00 80.77  ? 41  VAL c N   1 
ATOM 2907 C CA  . VAL D 3 42  ? 140.975 104.001 138.338 1.00 80.77  ? 41  VAL c CA  1 
ATOM 2908 C C   . VAL D 3 42  ? 139.663 104.257 139.068 1.00 80.77  ? 41  VAL c C   1 
ATOM 2909 O O   . VAL D 3 42  ? 138.951 105.217 138.741 1.00 80.77  ? 41  VAL c O   1 
ATOM 2910 C CB  . VAL D 3 42  ? 141.955 105.168 138.528 1.00 80.77  ? 41  VAL c CB  1 
ATOM 2911 C CG1 . VAL D 3 42  ? 141.930 105.643 139.966 1.00 80.77  ? 41  VAL c CG1 1 
ATOM 2912 C CG2 . VAL D 3 42  ? 143.361 104.755 138.141 1.00 80.77  ? 41  VAL c CG2 1 
ATOM 2913 N N   . PRO D 3 43  ? 139.296 103.426 140.044 1.00 76.04  ? 42  PRO c N   1 
ATOM 2914 C CA  . PRO D 3 43  ? 137.984 103.589 140.692 1.00 76.04  ? 42  PRO c CA  1 
ATOM 2915 C C   . PRO D 3 43  ? 137.799 104.919 141.402 1.00 76.04  ? 42  PRO c C   1 
ATOM 2916 O O   . PRO D 3 43  ? 136.657 105.364 141.565 1.00 76.04  ? 42  PRO c O   1 
ATOM 2917 C CB  . PRO D 3 43  ? 137.938 102.415 141.678 1.00 76.04  ? 42  PRO c CB  1 
ATOM 2918 C CG  . PRO D 3 43  ? 138.902 101.420 141.133 1.00 76.04  ? 42  PRO c CG  1 
ATOM 2919 C CD  . PRO D 3 43  ? 140.000 102.225 140.517 1.00 76.04  ? 42  PRO c CD  1 
ATOM 2920 N N   . ALA D 3 44  ? 138.877 105.565 141.843 1.00 78.34  ? 43  ALA c N   1 
ATOM 2921 C CA  . ALA D 3 44  ? 138.737 106.787 142.624 1.00 78.34  ? 43  ALA c CA  1 
ATOM 2922 C C   . ALA D 3 44  ? 138.644 108.044 141.770 1.00 78.34  ? 43  ALA c C   1 
ATOM 2923 O O   . ALA D 3 44  ? 138.291 109.104 142.297 1.00 78.34  ? 43  ALA c O   1 
ATOM 2924 C CB  . ALA D 3 44  ? 139.904 106.922 143.602 1.00 78.34  ? 43  ALA c CB  1 
ATOM 2925 N N   . LEU D 3 45  ? 138.949 107.962 140.478 1.00 81.69  ? 44  LEU c N   1 
ATOM 2926 C CA  . LEU D 3 45  ? 138.976 109.127 139.599 1.00 81.69  ? 44  LEU c CA  1 
ATOM 2927 C C   . LEU D 3 45  ? 138.014 108.976 138.425 1.00 81.69  ? 44  LEU c C   1 
ATOM 2928 O O   . LEU D 3 45  ? 138.354 109.278 137.281 1.00 81.69  ? 44  LEU c O   1 
ATOM 2929 C CB  . LEU D 3 45  ? 140.390 109.382 139.086 1.00 81.69  ? 44  LEU c CB  1 
ATOM 2930 C CG  . LEU D 3 45  ? 141.479 109.491 140.148 1.00 81.69  ? 44  LEU c CG  1 
ATOM 2931 C CD1 . LEU D 3 45  ? 142.847 109.560 139.497 1.00 81.69  ? 44  LEU c CD1 1 
ATOM 2932 C CD2 . LEU D 3 45  ? 141.237 110.703 141.021 1.00 81.69  ? 44  LEU c CD2 1 
ATOM 2933 N N   . GLU D 3 46  ? 136.801 108.509 138.694 1.00 75.81  ? 45  GLU c N   1 
ATOM 2934 C CA  . GLU D 3 46  ? 135.803 108.303 137.658 1.00 75.81  ? 45  GLU c CA  1 
ATOM 2935 C C   . GLU D 3 46  ? 134.518 109.045 137.999 1.00 75.81  ? 45  GLU c C   1 
ATOM 2936 O O   . GLU D 3 46  ? 134.141 109.171 139.167 1.00 75.81  ? 45  GLU c O   1 
ATOM 2937 C CB  . GLU D 3 46  ? 135.511 106.815 137.475 1.00 75.81  ? 45  GLU c CB  1 
ATOM 2938 C CG  . GLU D 3 46  ? 135.279 106.090 138.780 1.00 75.81  ? 45  GLU c CG  1 
ATOM 2939 C CD  . GLU D 3 46  ? 134.673 104.720 138.583 1.00 75.81  ? 45  GLU c CD  1 
ATOM 2940 O OE1 . GLU D 3 46  ? 135.179 103.962 137.729 1.00 75.81  ? 45  GLU c OE1 1 
ATOM 2941 O OE2 . GLU D 3 46  ? 133.692 104.395 139.285 1.00 75.81  ? 45  GLU c OE2 1 
ATOM 2942 N N   . LYS D 3 47  ? 133.851 109.538 136.961 1.00 70.95  ? 46  LYS c N   1 
ATOM 2943 C CA  . LYS D 3 47  ? 132.592 110.248 137.118 1.00 70.95  ? 46  LYS c CA  1 
ATOM 2944 C C   . LYS D 3 47  ? 131.477 109.249 137.387 1.00 70.95  ? 46  LYS c C   1 
ATOM 2945 O O   . LYS D 3 47  ? 131.401 108.209 136.727 1.00 70.95  ? 46  LYS c O   1 
ATOM 2946 C CB  . LYS D 3 47  ? 132.293 111.049 135.855 1.00 70.95  ? 46  LYS c CB  1 
ATOM 2947 C CG  . LYS D 3 47  ? 133.498 111.810 135.347 1.00 70.95  ? 46  LYS c CG  1 
ATOM 2948 C CD  . LYS D 3 47  ? 133.325 112.235 133.907 1.00 70.95  ? 46  LYS c CD  1 
ATOM 2949 C CE  . LYS D 3 47  ? 133.892 113.619 133.687 1.00 70.95  ? 46  LYS c CE  1 
ATOM 2950 N NZ  . LYS D 3 47  ? 135.378 113.604 133.704 1.00 70.95  ? 46  LYS c NZ  1 
ATOM 2951 N N   . ARG D 3 48  ? 130.613 109.551 138.352 1.00 64.58  ? 47  ARG c N   1 
ATOM 2952 C CA  . ARG D 3 48  ? 129.562 108.616 138.723 1.00 64.58  ? 47  ARG c CA  1 
ATOM 2953 C C   . ARG D 3 48  ? 128.218 109.316 138.843 1.00 64.58  ? 47  ARG c C   1 
ATOM 2954 O O   . ARG D 3 48  ? 128.133 110.513 139.139 1.00 64.58  ? 47  ARG c O   1 
ATOM 2955 C CB  . ARG D 3 48  ? 129.880 107.895 140.034 1.00 64.58  ? 47  ARG c CB  1 
ATOM 2956 C CG  . ARG D 3 48  ? 130.453 108.775 141.111 1.00 64.58  ? 47  ARG c CG  1 
ATOM 2957 C CD  . ARG D 3 48  ? 130.496 108.038 142.436 1.00 64.58  ? 47  ARG c CD  1 
ATOM 2958 N NE  . ARG D 3 48  ? 130.852 106.637 142.257 1.00 64.58  ? 47  ARG c NE  1 
ATOM 2959 C CZ  . ARG D 3 48  ? 132.096 106.181 142.222 1.00 64.58  ? 47  ARG c CZ  1 
ATOM 2960 N NH1 . ARG D 3 48  ? 133.133 106.991 142.361 1.00 64.58  ? 47  ARG c NH1 1 
ATOM 2961 N NH2 . ARG D 3 48  ? 132.306 104.880 142.043 1.00 64.58  ? 47  ARG c NH2 1 
ATOM 2962 N N   . VAL D 3 49  ? 127.166 108.538 138.600 1.00 58.73  ? 48  VAL c N   1 
ATOM 2963 C CA  . VAL D 3 49  ? 125.783 108.981 138.693 1.00 58.73  ? 48  VAL c CA  1 
ATOM 2964 C C   . VAL D 3 49  ? 125.026 107.976 139.546 1.00 58.73  ? 48  VAL c C   1 
ATOM 2965 O O   . VAL D 3 49  ? 125.285 106.771 139.473 1.00 58.73  ? 48  VAL c O   1 
ATOM 2966 C CB  . VAL D 3 49  ? 125.128 109.104 137.302 1.00 58.73  ? 48  VAL c CB  1 
ATOM 2967 C CG1 . VAL D 3 49  ? 123.794 109.807 137.409 1.00 58.73  ? 48  VAL c CG1 1 
ATOM 2968 C CG2 . VAL D 3 49  ? 126.043 109.833 136.340 1.00 58.73  ? 48  VAL c CG2 1 
ATOM 2969 N N   . THR D 3 50  ? 124.112 108.468 140.372 1.00 57.67  ? 49  THR c N   1 
ATOM 2970 C CA  . THR D 3 50  ? 123.238 107.617 141.164 1.00 57.67  ? 49  THR c CA  1 
ATOM 2971 C C   . THR D 3 50  ? 121.802 108.067 140.960 1.00 57.67  ? 49  THR c C   1 
ATOM 2972 O O   . THR D 3 50  ? 121.523 109.266 140.917 1.00 57.67  ? 49  THR c O   1 
ATOM 2973 C CB  . THR D 3 50  ? 123.585 107.664 142.656 1.00 57.67  ? 49  THR c CB  1 
ATOM 2974 O OG1 . THR D 3 50  ? 123.241 108.948 143.188 1.00 57.67  ? 49  THR c OG1 1 
ATOM 2975 C CG2 . THR D 3 50  ? 125.069 107.416 142.875 1.00 57.67  ? 49  THR c CG2 1 
ATOM 2976 N N   . VAL D 3 51  ? 120.896 107.105 140.828 1.00 57.46  ? 50  VAL c N   1 
ATOM 2977 C CA  . VAL D 3 51  ? 119.478 107.387 140.642 1.00 57.46  ? 50  VAL c CA  1 
ATOM 2978 C C   . VAL D 3 51  ? 118.677 106.472 141.554 1.00 57.46  ? 50  VAL c C   1 
ATOM 2979 O O   . VAL D 3 51  ? 119.008 105.292 141.710 1.00 57.46  ? 50  VAL c O   1 
ATOM 2980 C CB  . VAL D 3 51  ? 119.052 107.222 139.166 1.00 57.46  ? 50  VAL c CB  1 
ATOM 2981 C CG1 . VAL D 3 51  ? 119.283 105.802 138.690 1.00 57.46  ? 50  VAL c CG1 1 
ATOM 2982 C CG2 . VAL D 3 51  ? 117.598 107.615 138.983 1.00 57.46  ? 50  VAL c CG2 1 
ATOM 2983 N N   . SER D 3 52  ? 117.638 107.019 142.181 1.00 61.64  ? 51  SER c N   1 
ATOM 2984 C CA  . SER D 3 52  ? 116.823 106.223 143.092 1.00 61.64  ? 51  SER c CA  1 
ATOM 2985 C C   . SER D 3 52  ? 115.441 106.840 143.212 1.00 61.64  ? 51  SER c C   1 
ATOM 2986 O O   . SER D 3 52  ? 115.317 108.019 143.552 1.00 61.64  ? 51  SER c O   1 
ATOM 2987 C CB  . SER D 3 52  ? 117.479 106.126 144.467 1.00 61.64  ? 51  SER c CB  1 
ATOM 2988 O OG  . SER D 3 52  ? 117.373 107.353 145.165 1.00 61.64  ? 51  SER c OG  1 
ATOM 2989 N N   . VAL D 3 53  ? 114.409 106.045 142.954 1.00 67.37  ? 52  VAL c N   1 
ATOM 2990 C CA  . VAL D 3 53  ? 113.028 106.458 143.165 1.00 67.37  ? 52  VAL c CA  1 
ATOM 2991 C C   . VAL D 3 53  ? 112.486 105.717 144.378 1.00 67.37  ? 52  VAL c C   1 
ATOM 2992 O O   . VAL D 3 53  ? 112.667 104.501 144.510 1.00 67.37  ? 52  VAL c O   1 
ATOM 2993 C CB  . VAL D 3 53  ? 112.168 106.209 141.915 1.00 67.37  ? 52  VAL c CB  1 
ATOM 2994 C CG1 . VAL D 3 53  ? 112.200 104.757 141.519 1.00 67.37  ? 52  VAL c CG1 1 
ATOM 2995 C CG2 . VAL D 3 53  ? 110.740 106.647 142.167 1.00 67.37  ? 52  VAL c CG2 1 
ATOM 2996 N N   . SER D 3 54  ? 111.849 106.453 145.280 1.00 76.45  ? 53  SER c N   1 
ATOM 2997 C CA  . SER D 3 54  ? 111.390 105.896 146.541 1.00 76.45  ? 53  SER c CA  1 
ATOM 2998 C C   . SER D 3 54  ? 109.944 105.426 146.408 1.00 76.45  ? 53  SER c C   1 
ATOM 2999 O O   . SER D 3 54  ? 109.369 105.402 145.317 1.00 76.45  ? 53  SER c O   1 
ATOM 3000 C CB  . SER D 3 54  ? 111.553 106.924 147.658 1.00 76.45  ? 53  SER c CB  1 
ATOM 3001 O OG  . SER D 3 54  ? 111.082 106.415 148.893 1.00 76.45  ? 53  SER c OG  1 
ATOM 3002 N N   . GLN D 3 55  ? 109.346 105.041 147.530 1.00 84.82  ? 54  GLN c N   1 
ATOM 3003 C CA  . GLN D 3 55  ? 107.967 104.592 147.609 1.00 84.82  ? 54  GLN c CA  1 
ATOM 3004 C C   . GLN D 3 55  ? 107.268 105.327 148.742 1.00 84.82  ? 54  GLN c C   1 
ATOM 3005 O O   . GLN D 3 55  ? 107.909 105.709 149.725 1.00 84.82  ? 54  GLN c O   1 
ATOM 3006 C CB  . GLN D 3 55  ? 107.893 103.077 147.851 1.00 84.82  ? 54  GLN c CB  1 
ATOM 3007 C CG  . GLN D 3 55  ? 108.545 102.227 146.764 1.00 84.82  ? 54  GLN c CG  1 
ATOM 3008 C CD  . GLN D 3 55  ? 107.587 101.858 145.649 1.00 84.82  ? 54  GLN c CD  1 
ATOM 3009 O OE1 . GLN D 3 55  ? 106.415 101.572 145.890 1.00 84.82  ? 54  GLN c OE1 1 
ATOM 3010 N NE2 . GLN D 3 55  ? 108.085 101.853 144.419 1.00 84.82  ? 54  GLN c NE2 1 
ATOM 3011 N N   . PRO D 3 56  ? 105.949 105.543 148.633 1.00 84.68  ? 55  PRO c N   1 
ATOM 3012 C CA  . PRO D 3 56  ? 105.220 106.240 149.697 1.00 84.68  ? 55  PRO c CA  1 
ATOM 3013 C C   . PRO D 3 56  ? 105.073 105.394 150.957 1.00 84.68  ? 55  PRO c C   1 
ATOM 3014 O O   . PRO D 3 56  ? 105.413 104.212 150.926 1.00 84.68  ? 55  PRO c O   1 
ATOM 3015 C CB  . PRO D 3 56  ? 103.855 106.512 149.063 1.00 84.68  ? 55  PRO c CB  1 
ATOM 3016 C CG  . PRO D 3 56  ? 103.703 105.442 148.048 1.00 84.68  ? 55  PRO c CG  1 
ATOM 3017 C CD  . PRO D 3 56  ? 105.078 105.223 147.491 1.00 84.68  ? 55  PRO c CD  1 
ATOM 3018 N N   . LYS D 3 61  ? 103.483 111.027 152.245 1.00 84.70  ? 60  LYS c N   1 
ATOM 3019 C CA  . LYS D 3 61  ? 102.889 109.981 151.424 1.00 84.70  ? 60  LYS c CA  1 
ATOM 3020 C C   . LYS D 3 61  ? 102.952 110.378 149.952 1.00 84.70  ? 60  LYS c C   1 
ATOM 3021 O O   . LYS D 3 61  ? 101.929 110.658 149.328 1.00 84.70  ? 60  LYS c O   1 
ATOM 3022 C CB  . LYS D 3 61  ? 101.442 109.720 151.851 1.00 84.70  ? 60  LYS c CB  1 
ATOM 3023 C CG  . LYS D 3 61  ? 100.825 108.455 151.271 1.00 84.70  ? 60  LYS c CG  1 
ATOM 3024 C CD  . LYS D 3 61  ? 101.424 107.211 151.912 1.00 84.70  ? 60  LYS c CD  1 
ATOM 3025 C CE  . LYS D 3 61  ? 100.680 105.950 151.497 1.00 84.70  ? 60  LYS c CE  1 
ATOM 3026 N NZ  . LYS D 3 61  ? 100.868 105.629 150.057 1.00 84.70  ? 60  LYS c NZ  1 
ATOM 3027 N N   . ASN D 3 62  ? 104.164 110.409 149.405 1.00 77.37  ? 61  ASN c N   1 
ATOM 3028 C CA  . ASN D 3 62  ? 104.362 110.811 148.021 1.00 77.37  ? 61  ASN c CA  1 
ATOM 3029 C C   . ASN D 3 62  ? 105.681 110.250 147.509 1.00 77.37  ? 61  ASN c C   1 
ATOM 3030 O O   . ASN D 3 62  ? 106.578 109.913 148.284 1.00 77.37  ? 61  ASN c O   1 
ATOM 3031 C CB  . ASN D 3 62  ? 104.295 112.338 147.875 1.00 77.37  ? 61  ASN c CB  1 
ATOM 3032 C CG  . ASN D 3 62  ? 105.400 113.061 148.633 1.00 77.37  ? 61  ASN c CG  1 
ATOM 3033 O OD1 . ASN D 3 62  ? 106.310 112.447 149.187 1.00 77.37  ? 61  ASN c OD1 1 
ATOM 3034 N ND2 . ASN D 3 62  ? 105.315 114.385 148.662 1.00 77.37  ? 61  ASN c ND2 1 
ATOM 3035 N N   . TYR D 3 63  ? 105.775 110.143 146.187 1.00 71.72  ? 62  TYR c N   1 
ATOM 3036 C CA  . TYR D 3 63  ? 106.980 109.633 145.555 1.00 71.72  ? 62  TYR c CA  1 
ATOM 3037 C C   . TYR D 3 63  ? 108.078 110.691 145.562 1.00 71.72  ? 62  TYR c C   1 
ATOM 3038 O O   . TYR D 3 63  ? 107.822 111.891 145.675 1.00 71.72  ? 62  TYR c O   1 
ATOM 3039 C CB  . TYR D 3 63  ? 106.687 109.188 144.125 1.00 71.72  ? 62  TYR c CB  1 
ATOM 3040 C CG  . TYR D 3 63  ? 105.765 107.998 144.044 1.00 71.72  ? 62  TYR c CG  1 
ATOM 3041 C CD1 . TYR D 3 63  ? 104.390 108.160 144.041 1.00 71.72  ? 62  TYR c CD1 1 
ATOM 3042 C CD2 . TYR D 3 63  ? 106.272 106.710 143.974 1.00 71.72  ? 62  TYR c CD2 1 
ATOM 3043 C CE1 . TYR D 3 63  ? 103.545 107.075 143.971 1.00 71.72  ? 62  TYR c CE1 1 
ATOM 3044 C CE2 . TYR D 3 63  ? 105.435 105.618 143.902 1.00 71.72  ? 62  TYR c CE2 1 
ATOM 3045 C CZ  . TYR D 3 63  ? 104.073 105.806 143.901 1.00 71.72  ? 62  TYR c CZ  1 
ATOM 3046 O OH  . TYR D 3 63  ? 103.233 104.720 143.830 1.00 71.72  ? 62  TYR c OH  1 
ATOM 3047 N N   . LYS D 3 64  ? 109.319 110.228 145.440 1.00 65.67  ? 63  LYS c N   1 
ATOM 3048 C CA  . LYS D 3 64  ? 110.469 111.127 145.452 1.00 65.67  ? 63  LYS c CA  1 
ATOM 3049 C C   . LYS D 3 64  ? 111.581 110.499 144.627 1.00 65.67  ? 63  LYS c C   1 
ATOM 3050 O O   . LYS D 3 64  ? 112.058 109.409 144.954 1.00 65.67  ? 63  LYS c O   1 
ATOM 3051 C CB  . LYS D 3 64  ? 110.935 111.402 146.876 1.00 65.67  ? 63  LYS c CB  1 
ATOM 3052 C CG  . LYS D 3 64  ? 112.211 112.218 146.951 1.00 65.67  ? 63  LYS c CG  1 
ATOM 3053 C CD  . LYS D 3 64  ? 112.801 112.216 148.352 1.00 65.67  ? 63  LYS c CD  1 
ATOM 3054 C CE  . LYS D 3 64  ? 111.759 112.548 149.409 1.00 65.67  ? 63  LYS c CE  1 
ATOM 3055 N NZ  . LYS D 3 64  ? 110.936 113.739 149.049 1.00 65.67  ? 63  LYS c NZ  1 
ATOM 3056 N N   . VAL D 3 65  ? 111.995 111.190 143.572 1.00 59.06  ? 64  VAL c N   1 
ATOM 3057 C CA  . VAL D 3 65  ? 113.047 110.721 142.676 1.00 59.06  ? 64  VAL c CA  1 
ATOM 3058 C C   . VAL D 3 65  ? 114.296 111.547 142.929 1.00 59.06  ? 64  VAL c C   1 
ATOM 3059 O O   . VAL D 3 65  ? 114.249 112.780 142.876 1.00 59.06  ? 64  VAL c O   1 
ATOM 3060 C CB  . VAL D 3 65  ? 112.611 110.830 141.207 1.00 59.06  ? 64  VAL c CB  1 
ATOM 3061 C CG1 . VAL D 3 65  ? 113.694 110.286 140.297 1.00 59.06  ? 64  VAL c CG1 1 
ATOM 3062 C CG2 . VAL D 3 65  ? 111.300 110.099 140.991 1.00 59.06  ? 64  VAL c CG2 1 
ATOM 3063 N N   . GLN D 3 66  ? 115.417 110.882 143.192 1.00 57.89  ? 65  GLN c N   1 
ATOM 3064 C CA  . GLN D 3 66  ? 116.654 111.571 143.525 1.00 57.89  ? 65  GLN c CA  1 
ATOM 3065 C C   . GLN D 3 66  ? 117.758 111.130 142.579 1.00 57.89  ? 65  GLN c C   1 
ATOM 3066 O O   . GLN D 3 66  ? 117.985 109.929 142.396 1.00 57.89  ? 65  GLN c O   1 
ATOM 3067 C CB  . GLN D 3 66  ? 117.057 111.303 144.975 1.00 57.89  ? 65  GLN c CB  1 
ATOM 3068 C CG  . GLN D 3 66  ? 118.300 112.045 145.406 1.00 57.89  ? 65  GLN c CG  1 
ATOM 3069 C CD  . GLN D 3 66  ? 118.210 112.522 146.837 1.00 57.89  ? 65  GLN c CD  1 
ATOM 3070 O OE1 . GLN D 3 66  ? 117.352 112.077 147.597 1.00 57.89  ? 65  GLN c OE1 1 
ATOM 3071 N NE2 . GLN D 3 66  ? 119.091 113.442 147.211 1.00 57.89  ? 65  GLN c NE2 1 
ATOM 3072 N N   . VAL D 3 67  ? 118.441 112.106 141.986 1.00 54.07  ? 66  VAL c N   1 
ATOM 3073 C CA  . VAL D 3 67  ? 119.537 111.870 141.056 1.00 54.07  ? 66  VAL c CA  1 
ATOM 3074 C C   . VAL D 3 67  ? 120.737 112.683 141.514 1.00 54.07  ? 66  VAL c C   1 
ATOM 3075 O O   . VAL D 3 67  ? 120.635 113.900 141.691 1.00 54.07  ? 66  VAL c O   1 
ATOM 3076 C CB  . VAL D 3 67  ? 119.155 112.251 139.615 1.00 54.07  ? 66  VAL c CB  1 
ATOM 3077 C CG1 . VAL D 3 67  ? 120.372 112.191 138.713 1.00 54.07  ? 66  VAL c CG1 1 
ATOM 3078 C CG2 . VAL D 3 67  ? 118.058 111.342 139.100 1.00 54.07  ? 66  VAL c CG2 1 
ATOM 3079 N N   . LYS D 3 68  ? 121.872 112.020 141.689 1.00 55.72  ? 67  LYS c N   1 
ATOM 3080 C CA  . LYS D 3 68  ? 123.105 112.674 142.098 1.00 55.72  ? 67  LYS c CA  1 
ATOM 3081 C C   . LYS D 3 68  ? 124.180 112.439 141.050 1.00 55.72  ? 67  LYS c C   1 
ATOM 3082 O O   . LYS D 3 68  ? 124.305 111.338 140.513 1.00 55.72  ? 67  LYS c O   1 
ATOM 3083 C CB  . LYS D 3 68  ? 123.591 112.163 143.451 1.00 55.72  ? 67  LYS c CB  1 
ATOM 3084 C CG  . LYS D 3 68  ? 122.546 112.201 144.541 1.00 55.72  ? 67  LYS c CG  1 
ATOM 3085 C CD  . LYS D 3 68  ? 123.196 112.198 145.910 1.00 55.72  ? 67  LYS c CD  1 
ATOM 3086 C CE  . LYS D 3 68  ? 122.158 112.231 147.014 1.00 55.72  ? 67  LYS c CE  1 
ATOM 3087 N NZ  . LYS D 3 68  ? 122.781 112.403 148.354 1.00 55.72  ? 67  LYS c NZ  1 
ATOM 3088 N N   . ILE D 3 69  ? 124.944 113.484 140.756 1.00 54.53  ? 68  ILE c N   1 
ATOM 3089 C CA  . ILE D 3 69  ? 126.082 113.413 139.851 1.00 54.53  ? 68  ILE c CA  1 
ATOM 3090 C C   . ILE D 3 69  ? 127.306 113.868 140.625 1.00 54.53  ? 68  ILE c C   1 
ATOM 3091 O O   . ILE D 3 69  ? 127.265 114.900 141.302 1.00 54.53  ? 68  ILE c O   1 
ATOM 3092 C CB  . ILE D 3 69  ? 125.871 114.279 138.597 1.00 54.53  ? 68  ILE c CB  1 
ATOM 3093 C CG1 . ILE D 3 69  ? 124.681 113.766 137.792 1.00 54.53  ? 68  ILE c CG1 1 
ATOM 3094 C CG2 . ILE D 3 69  ? 127.119 114.289 137.738 1.00 54.53  ? 68  ILE c CG2 1 
ATOM 3095 C CD1 . ILE D 3 69  ? 124.250 114.705 136.694 1.00 54.53  ? 68  ILE c CD1 1 
ATOM 3096 N N   . GLN D 3 70  ? 128.387 113.100 140.534 1.00 64.09  ? 69  GLN c N   1 
ATOM 3097 C CA  . GLN D 3 70  ? 129.612 113.406 141.270 1.00 64.09  ? 69  GLN c CA  1 
ATOM 3098 C C   . GLN D 3 70  ? 130.807 113.106 140.375 1.00 64.09  ? 69  GLN c C   1 
ATOM 3099 O O   . GLN D 3 70  ? 130.989 111.966 139.940 1.00 64.09  ? 69  GLN c O   1 
ATOM 3100 C CB  . GLN D 3 70  ? 129.672 112.615 142.569 1.00 64.09  ? 69  GLN c CB  1 
ATOM 3101 C CG  . GLN D 3 70  ? 130.828 112.995 143.456 1.00 64.09  ? 69  GLN c CG  1 
ATOM 3102 C CD  . GLN D 3 70  ? 132.040 112.125 143.176 1.00 64.09  ? 69  GLN c CD  1 
ATOM 3103 O OE1 . GLN D 3 70  ? 131.900 110.959 142.823 1.00 64.09  ? 69  GLN c OE1 1 
ATOM 3104 N NE2 . GLN D 3 70  ? 133.229 112.697 143.289 1.00 64.09  ? 69  GLN c NE2 1 
ATOM 3105 N N   . ASN D 3 71  ? 131.618 114.125 140.100 1.00 65.90  ? 70  ASN c N   1 
ATOM 3106 C CA  . ASN D 3 71  ? 132.820 113.898 139.319 1.00 65.90  ? 70  ASN c CA  1 
ATOM 3107 C C   . ASN D 3 71  ? 134.013 114.592 139.960 1.00 65.90  ? 70  ASN c C   1 
ATOM 3108 O O   . ASN D 3 71  ? 133.934 115.785 140.285 1.00 65.90  ? 70  ASN c O   1 
ATOM 3109 C CB  . ASN D 3 71  ? 132.646 114.382 137.872 1.00 65.90  ? 70  ASN c CB  1 
ATOM 3110 C CG  . ASN D 3 71  ? 132.035 115.752 137.787 1.00 65.90  ? 70  ASN c CG  1 
ATOM 3111 O OD1 . ASN D 3 71  ? 131.535 116.281 138.775 1.00 65.90  ? 70  ASN c OD1 1 
ATOM 3112 N ND2 . ASN D 3 71  ? 132.070 116.341 136.600 1.00 65.90  ? 70  ASN c ND2 1 
ATOM 3113 N N   . PRO D 3 72  ? 135.119 113.890 140.169 1.00 71.96  ? 71  PRO c N   1 
ATOM 3114 C CA  . PRO D 3 72  ? 136.304 114.507 140.761 1.00 71.96  ? 71  PRO c CA  1 
ATOM 3115 C C   . PRO D 3 72  ? 137.278 114.988 139.692 1.00 71.96  ? 71  PRO c C   1 
ATOM 3116 O O   . PRO D 3 72  ? 137.156 114.670 138.508 1.00 71.96  ? 71  PRO c O   1 
ATOM 3117 C CB  . PRO D 3 72  ? 136.912 113.359 141.575 1.00 71.96  ? 71  PRO c CB  1 
ATOM 3118 C CG  . PRO D 3 72  ? 136.460 112.104 140.862 1.00 71.96  ? 71  PRO c CG  1 
ATOM 3119 C CD  . PRO D 3 72  ? 135.305 112.447 139.952 1.00 71.96  ? 71  PRO c CD  1 
ATOM 3120 N N   . THR D 3 73  ? 138.258 115.769 140.140 1.00 81.83  ? 72  THR c N   1 
ATOM 3121 C CA  . THR D 3 73  ? 139.352 116.225 139.297 1.00 81.83  ? 72  THR c CA  1 
ATOM 3122 C C   . THR D 3 73  ? 140.660 115.712 139.874 1.00 81.83  ? 72  THR c C   1 
ATOM 3123 O O   . THR D 3 73  ? 140.946 115.923 141.058 1.00 81.83  ? 72  THR c O   1 
ATOM 3124 C CB  . THR D 3 73  ? 139.379 117.750 139.196 1.00 81.83  ? 72  THR c CB  1 
ATOM 3125 O OG1 . THR D 3 73  ? 138.134 118.216 138.662 1.00 81.83  ? 72  THR c OG1 1 
ATOM 3126 C CG2 . THR D 3 73  ? 140.512 118.200 138.291 1.00 81.83  ? 72  THR c CG2 1 
ATOM 3127 N N   . ALA D 3 74  ? 141.449 115.046 139.041 1.00 92.74  ? 73  ALA c N   1 
ATOM 3128 C CA  . ALA D 3 74  ? 142.681 114.418 139.486 1.00 92.74  ? 73  ALA c CA  1 
ATOM 3129 C C   . ALA D 3 74  ? 143.856 115.381 139.374 1.00 92.74  ? 73  ALA c C   1 
ATOM 3130 O O   . ALA D 3 74  ? 143.823 116.362 138.628 1.00 92.74  ? 73  ALA c O   1 
ATOM 3131 C CB  . ALA D 3 74  ? 142.962 113.156 138.672 1.00 92.74  ? 73  ALA c CB  1 
ATOM 3132 N N   . CYS D 3 75  ? 144.906 115.083 140.135 1.00 108.89 ? 74  CYS c N   1 
ATOM 3133 C CA  . CYS D 3 75  ? 146.139 115.852 140.087 1.00 108.89 ? 74  CYS c CA  1 
ATOM 3134 C C   . CYS D 3 75  ? 147.287 114.956 140.524 1.00 108.89 ? 74  CYS c C   1 
ATOM 3135 O O   . CYS D 3 75  ? 147.103 114.033 141.322 1.00 108.89 ? 74  CYS c O   1 
ATOM 3136 C CB  . CYS D 3 75  ? 146.069 117.097 140.978 1.00 108.89 ? 74  CYS c CB  1 
ATOM 3137 S SG  . CYS D 3 75  ? 146.280 116.765 142.741 1.00 108.89 ? 74  CYS c SG  1 
ATOM 3138 N N   . THR D 3 76  ? 148.472 115.238 139.997 1.00 123.22 ? 75  THR c N   1 
ATOM 3139 C CA  . THR D 3 76  ? 149.678 114.472 140.301 1.00 123.22 ? 75  THR c CA  1 
ATOM 3140 C C   . THR D 3 76  ? 150.579 115.344 141.172 1.00 123.22 ? 75  THR c C   1 
ATOM 3141 O O   . THR D 3 76  ? 151.461 116.046 140.675 1.00 123.22 ? 75  THR c O   1 
ATOM 3142 C CB  . THR D 3 76  ? 150.386 114.034 139.024 1.00 123.22 ? 75  THR c CB  1 
ATOM 3143 O OG1 . THR D 3 76  ? 150.795 115.190 138.283 1.00 123.22 ? 75  THR c OG1 1 
ATOM 3144 C CG2 . THR D 3 76  ? 149.454 113.194 138.165 1.00 123.22 ? 75  THR c CG2 1 
ATOM 3145 N N   . ALA D 3 77  ? 150.348 115.293 142.480 1.00 129.97 ? 76  ALA c N   1 
ATOM 3146 C CA  . ALA D 3 77  ? 151.147 116.062 143.419 1.00 129.97 ? 76  ALA c CA  1 
ATOM 3147 C C   . ALA D 3 77  ? 152.505 115.405 143.632 1.00 129.97 ? 76  ALA c C   1 
ATOM 3148 O O   . ALA D 3 77  ? 152.652 114.184 143.528 1.00 129.97 ? 76  ALA c O   1 
ATOM 3149 C CB  . ALA D 3 77  ? 150.420 116.202 144.756 1.00 129.97 ? 76  ALA c CB  1 
ATOM 3150 N N   . ASN D 3 78  ? 153.502 116.232 143.932 1.00 136.03 ? 77  ASN c N   1 
ATOM 3151 C CA  . ASN D 3 78  ? 154.841 115.726 144.182 1.00 136.03 ? 77  ASN c CA  1 
ATOM 3152 C C   . ASN D 3 78  ? 154.886 114.953 145.498 1.00 136.03 ? 77  ASN c C   1 
ATOM 3153 O O   . ASN D 3 78  ? 154.059 115.144 146.394 1.00 136.03 ? 77  ASN c O   1 
ATOM 3154 C CB  . ASN D 3 78  ? 155.853 116.871 144.210 1.00 136.03 ? 77  ASN c CB  1 
ATOM 3155 C CG  . ASN D 3 78  ? 156.257 117.322 142.821 1.00 136.03 ? 77  ASN c CG  1 
ATOM 3156 O OD1 . ASN D 3 78  ? 156.470 116.503 141.927 1.00 136.03 ? 77  ASN c OD1 1 
ATOM 3157 N ND2 . ASN D 3 78  ? 156.364 118.632 142.633 1.00 136.03 ? 77  ASN c ND2 1 
ATOM 3158 N N   . GLY D 3 79  ? 155.872 114.065 145.602 1.00 134.85 ? 78  GLY c N   1 
ATOM 3159 C CA  . GLY D 3 79  ? 156.019 113.223 146.769 1.00 134.85 ? 78  GLY c CA  1 
ATOM 3160 C C   . GLY D 3 79  ? 155.161 111.978 146.775 1.00 134.85 ? 78  GLY c C   1 
ATOM 3161 O O   . GLY D 3 79  ? 155.157 111.256 147.780 1.00 134.85 ? 78  GLY c O   1 
ATOM 3162 N N   . SER D 3 80  ? 154.435 111.702 145.695 1.00 132.08 ? 79  SER c N   1 
ATOM 3163 C CA  . SER D 3 80  ? 153.589 110.522 145.616 1.00 132.08 ? 79  SER c CA  1 
ATOM 3164 C C   . SER D 3 80  ? 153.481 110.091 144.162 1.00 132.08 ? 79  SER c C   1 
ATOM 3165 O O   . SER D 3 80  ? 153.745 110.868 143.242 1.00 132.08 ? 79  SER c O   1 
ATOM 3166 C CB  . SER D 3 80  ? 152.199 110.785 146.208 1.00 132.08 ? 79  SER c CB  1 
ATOM 3167 O OG  . SER D 3 80  ? 152.260 110.892 147.619 1.00 132.08 ? 79  SER c OG  1 
ATOM 3168 N N   . CYS D 3 81  ? 153.088 108.834 143.965 1.00 127.43 ? 80  CYS c N   1 
ATOM 3169 C CA  . CYS D 3 81  ? 152.958 108.265 142.631 1.00 127.43 ? 80  CYS c CA  1 
ATOM 3170 C C   . CYS D 3 81  ? 151.518 108.088 142.178 1.00 127.43 ? 80  CYS c C   1 
ATOM 3171 O O   . CYS D 3 81  ? 151.226 108.307 141.001 1.00 127.43 ? 80  CYS c O   1 
ATOM 3172 C CB  . CYS D 3 81  ? 153.669 106.908 142.560 1.00 127.43 ? 80  CYS c CB  1 
ATOM 3173 S SG  . CYS D 3 81  ? 155.472 107.017 142.527 1.00 127.43 ? 80  CYS c SG  1 
ATOM 3174 N N   . ASP D 3 82  ? 150.615 107.700 143.076 1.00 121.06 ? 81  ASP c N   1 
ATOM 3175 C CA  . ASP D 3 82  ? 149.214 107.522 142.720 1.00 121.06 ? 81  ASP c CA  1 
ATOM 3176 C C   . ASP D 3 82  ? 148.481 108.850 142.846 1.00 121.06 ? 81  ASP c C   1 
ATOM 3177 O O   . ASP D 3 82  ? 148.484 109.443 143.933 1.00 121.06 ? 81  ASP c O   1 
ATOM 3178 C CB  . ASP D 3 82  ? 148.562 106.479 143.611 1.00 121.06 ? 81  ASP c CB  1 
ATOM 3179 C CG  . ASP D 3 82  ? 148.934 105.061 143.219 1.00 121.06 ? 81  ASP c CG  1 
ATOM 3180 O OD1 . ASP D 3 82  ? 149.197 104.824 142.021 1.00 121.06 ? 81  ASP c OD1 1 
ATOM 3181 O OD2 . ASP D 3 82  ? 148.964 104.184 144.107 1.00 121.06 ? 81  ASP c OD2 1 
ATOM 3182 N N   . PRO D 3 83  ? 147.859 109.353 141.781 1.00 112.13 ? 82  PRO c N   1 
ATOM 3183 C CA  . PRO D 3 83  ? 147.168 110.644 141.872 1.00 112.13 ? 82  PRO c CA  1 
ATOM 3184 C C   . PRO D 3 83  ? 146.020 110.597 142.870 1.00 112.13 ? 82  PRO c C   1 
ATOM 3185 O O   . PRO D 3 83  ? 145.322 109.590 142.997 1.00 112.13 ? 82  PRO c O   1 
ATOM 3186 C CB  . PRO D 3 83  ? 146.664 110.878 140.444 1.00 112.13 ? 82  PRO c CB  1 
ATOM 3187 C CG  . PRO D 3 83  ? 146.593 109.514 139.842 1.00 112.13 ? 82  PRO c CG  1 
ATOM 3188 C CD  . PRO D 3 83  ? 147.734 108.752 140.443 1.00 112.13 ? 82  PRO c CD  1 
ATOM 3189 N N   . SER D 3 84  ? 145.833 111.703 143.579 1.00 101.34 ? 83  SER c N   1 
ATOM 3190 C CA  . SER D 3 84  ? 144.786 111.835 144.574 1.00 101.34 ? 83  SER c CA  1 
ATOM 3191 C C   . SER D 3 84  ? 143.638 112.667 144.008 1.00 101.34 ? 83  SER c C   1 
ATOM 3192 O O   . SER D 3 84  ? 143.608 113.005 142.821 1.00 101.34 ? 83  SER c O   1 
ATOM 3193 C CB  . SER D 3 84  ? 145.356 112.447 145.854 1.00 101.34 ? 83  SER c CB  1 
ATOM 3194 O OG  . SER D 3 84  ? 145.780 113.780 145.635 1.00 101.34 ? 83  SER c OG  1 
ATOM 3195 N N   . VAL D 3 85  ? 142.677 113.002 144.863 1.00 93.59  ? 84  VAL c N   1 
ATOM 3196 C CA  . VAL D 3 85  ? 141.525 113.814 144.488 1.00 93.59  ? 84  VAL c CA  1 
ATOM 3197 C C   . VAL D 3 85  ? 141.718 115.200 145.086 1.00 93.59  ? 84  VAL c C   1 
ATOM 3198 O O   . VAL D 3 85  ? 141.854 115.344 146.307 1.00 93.59  ? 84  VAL c O   1 
ATOM 3199 C CB  . VAL D 3 85  ? 140.209 113.184 144.967 1.00 93.59  ? 84  VAL c CB  1 
ATOM 3200 C CG1 . VAL D 3 85  ? 139.090 114.206 144.928 1.00 93.59  ? 84  VAL c CG1 1 
ATOM 3201 C CG2 . VAL D 3 85  ? 139.862 111.981 144.115 1.00 93.59  ? 84  VAL c CG2 1 
ATOM 3202 N N   . THR D 3 86  ? 141.731 116.220 144.228 1.00 91.29  ? 85  THR c N   1 
ATOM 3203 C CA  . THR D 3 86  ? 141.928 117.595 144.675 1.00 91.29  ? 85  THR c CA  1 
ATOM 3204 C C   . THR D 3 86  ? 140.597 118.303 144.909 1.00 91.29  ? 85  THR c C   1 
ATOM 3205 O O   . THR D 3 86  ? 140.317 118.768 146.019 1.00 91.29  ? 85  THR c O   1 
ATOM 3206 C CB  . THR D 3 86  ? 142.768 118.367 143.652 1.00 91.29  ? 85  THR c CB  1 
ATOM 3207 O OG1 . THR D 3 86  ? 144.102 117.847 143.636 1.00 91.29  ? 85  THR c OG1 1 
ATOM 3208 C CG2 . THR D 3 86  ? 142.811 119.843 144.003 1.00 91.29  ? 85  THR c CG2 1 
ATOM 3209 N N   . ARG D 3 87  ? 139.767 118.387 143.873 1.00 83.29  ? 86  ARG c N   1 
ATOM 3210 C CA  . ARG D 3 87  ? 138.474 119.043 143.962 1.00 83.29  ? 86  ARG c CA  1 
ATOM 3211 C C   . ARG D 3 87  ? 137.416 118.130 143.363 1.00 83.29  ? 86  ARG c C   1 
ATOM 3212 O O   . ARG D 3 87  ? 137.717 117.205 142.605 1.00 83.29  ? 86  ARG c O   1 
ATOM 3213 C CB  . ARG D 3 87  ? 138.481 120.409 143.265 1.00 83.29  ? 86  ARG c CB  1 
ATOM 3214 C CG  . ARG D 3 87  ? 138.838 120.359 141.799 1.00 83.29  ? 86  ARG c CG  1 
ATOM 3215 C CD  . ARG D 3 87  ? 139.065 121.756 141.258 1.00 83.29  ? 86  ARG c CD  1 
ATOM 3216 N NE  . ARG D 3 87  ? 139.482 121.735 139.862 1.00 83.29  ? 86  ARG c NE  1 
ATOM 3217 C CZ  . ARG D 3 87  ? 140.739 121.599 139.462 1.00 83.29  ? 86  ARG c CZ  1 
ATOM 3218 N NH1 . ARG D 3 87  ? 141.729 121.466 140.328 1.00 83.29  ? 86  ARG c NH1 1 
ATOM 3219 N NH2 . ARG D 3 87  ? 141.008 121.596 138.160 1.00 83.29  ? 86  ARG c NH2 1 
ATOM 3220 N N   . GLN D 3 88  ? 136.167 118.396 143.726 1.00 71.08  ? 87  GLN c N   1 
ATOM 3221 C CA  . GLN D 3 88  ? 135.075 117.468 143.488 1.00 71.08  ? 87  GLN c CA  1 
ATOM 3222 C C   . GLN D 3 88  ? 133.804 118.247 143.187 1.00 71.08  ? 87  GLN c C   1 
ATOM 3223 O O   . GLN D 3 88  ? 133.357 119.050 144.009 1.00 71.08  ? 87  GLN c O   1 
ATOM 3224 C CB  . GLN D 3 88  ? 134.898 116.569 144.715 1.00 71.08  ? 87  GLN c CB  1 
ATOM 3225 C CG  . GLN D 3 88  ? 133.862 115.491 144.610 1.00 71.08  ? 87  GLN c CG  1 
ATOM 3226 C CD  . GLN D 3 88  ? 133.823 114.637 145.862 1.00 71.08  ? 87  GLN c CD  1 
ATOM 3227 O OE1 . GLN D 3 88  ? 134.559 114.887 146.815 1.00 71.08  ? 87  GLN c OE1 1 
ATOM 3228 N NE2 . GLN D 3 88  ? 132.938 113.650 145.884 1.00 71.08  ? 87  GLN c NE2 1 
ATOM 3229 N N   . ALA D 3 89  ? 133.221 118.009 142.015 1.00 63.68  ? 88  ALA c N   1 
ATOM 3230 C CA  . ALA D 3 89  ? 132.040 118.734 141.570 1.00 63.68  ? 88  ALA c CA  1 
ATOM 3231 C C   . ALA D 3 89  ? 130.804 117.868 141.763 1.00 63.68  ? 88  ALA c C   1 
ATOM 3232 O O   . ALA D 3 89  ? 130.804 116.682 141.410 1.00 63.68  ? 88  ALA c O   1 
ATOM 3233 C CB  . ALA D 3 89  ? 132.174 119.153 140.107 1.00 63.68  ? 88  ALA c CB  1 
ATOM 3234 N N   . TYR D 3 90  ? 129.757 118.469 142.321 1.00 57.96  ? 89  TYR c N   1 
ATOM 3235 C CA  . TYR D 3 90  ? 128.524 117.787 142.673 1.00 57.96  ? 89  TYR c CA  1 
ATOM 3236 C C   . TYR D 3 90  ? 127.358 118.321 141.854 1.00 57.96  ? 89  TYR c C   1 
ATOM 3237 O O   . TYR D 3 90  ? 127.436 119.382 141.231 1.00 57.96  ? 89  TYR c O   1 
ATOM 3238 C CB  . TYR D 3 90  ? 128.197 117.957 144.159 1.00 57.96  ? 89  TYR c CB  1 
ATOM 3239 C CG  . TYR D 3 90  ? 129.088 117.195 145.107 1.00 57.96  ? 89  TYR c CG  1 
ATOM 3240 C CD1 . TYR D 3 90  ? 130.403 117.577 145.316 1.00 57.96  ? 89  TYR c CD1 1 
ATOM 3241 C CD2 . TYR D 3 90  ? 128.606 116.098 145.804 1.00 57.96  ? 89  TYR c CD2 1 
ATOM 3242 C CE1 . TYR D 3 90  ? 131.211 116.887 146.192 1.00 57.96  ? 89  TYR c CE1 1 
ATOM 3243 C CE2 . TYR D 3 90  ? 129.409 115.400 146.677 1.00 57.96  ? 89  TYR c CE2 1 
ATOM 3244 C CZ  . TYR D 3 90  ? 130.712 115.797 146.866 1.00 57.96  ? 89  TYR c CZ  1 
ATOM 3245 O OH  . TYR D 3 90  ? 131.516 115.102 147.738 1.00 57.96  ? 89  TYR c OH  1 
ATOM 3246 N N   . ALA D 3 91  ? 126.274 117.553 141.859 1.00 51.99  ? 90  ALA c N   1 
ATOM 3247 C CA  . ALA D 3 91  ? 125.009 117.972 141.275 1.00 51.99  ? 90  ALA c CA  1 
ATOM 3248 C C   . ALA D 3 91  ? 123.909 117.125 141.891 1.00 51.99  ? 90  ALA c C   1 
ATOM 3249 O O   . ALA D 3 91  ? 124.064 115.912 142.026 1.00 51.99  ? 90  ALA c O   1 
ATOM 3250 C CB  . ALA D 3 91  ? 125.012 117.820 139.752 1.00 51.99  ? 90  ALA c CB  1 
ATOM 3251 N N   . ASP D 3 92  ? 122.804 117.762 142.261 1.00 57.88  ? 91  ASP c N   1 
ATOM 3252 C CA  . ASP D 3 92  ? 121.707 117.074 142.923 1.00 57.88  ? 91  ASP c CA  1 
ATOM 3253 C C   . ASP D 3 92  ? 120.388 117.454 142.270 1.00 57.88  ? 91  ASP c C   1 
ATOM 3254 O O   . ASP D 3 92  ? 120.205 118.596 141.845 1.00 57.88  ? 91  ASP c O   1 
ATOM 3255 C CB  . ASP D 3 92  ? 121.668 117.410 144.413 1.00 57.88  ? 91  ASP c CB  1 
ATOM 3256 C CG  . ASP D 3 92  ? 120.842 116.425 145.209 1.00 57.88  ? 91  ASP c CG  1 
ATOM 3257 O OD1 . ASP D 3 92  ? 119.622 116.330 144.961 1.00 57.88  ? 91  ASP c OD1 1 
ATOM 3258 O OD2 . ASP D 3 92  ? 121.414 115.744 146.084 1.00 57.88  ? 91  ASP c OD2 1 
ATOM 3259 N N   . VAL D 3 93  ? 119.479 116.487 142.182 1.00 54.95  ? 92  VAL c N   1 
ATOM 3260 C CA  . VAL D 3 93  ? 118.139 116.696 141.648 1.00 54.95  ? 92  VAL c CA  1 
ATOM 3261 C C   . VAL D 3 93  ? 117.171 115.871 142.480 1.00 54.95  ? 92  VAL c C   1 
ATOM 3262 O O   . VAL D 3 93  ? 117.439 114.702 142.773 1.00 54.95  ? 92  VAL c O   1 
ATOM 3263 C CB  . VAL D 3 93  ? 118.052 116.302 140.159 1.00 54.95  ? 92  VAL c CB  1 
ATOM 3264 C CG1 . VAL D 3 93  ? 116.610 116.171 139.731 1.00 54.95  ? 92  VAL c CG1 1 
ATOM 3265 C CG2 . VAL D 3 93  ? 118.763 117.322 139.295 1.00 54.95  ? 92  VAL c CG2 1 
ATOM 3266 N N   . THR D 3 94  ? 116.041 116.468 142.858 1.00 58.18  ? 93  THR c N   1 
ATOM 3267 C CA  . THR D 3 94  ? 115.057 115.751 143.668 1.00 58.18  ? 93  THR c CA  1 
ATOM 3268 C C   . THR D 3 94  ? 113.647 116.184 143.261 1.00 58.18  ? 93  THR c C   1 
ATOM 3269 O O   . THR D 3 94  ? 113.181 117.266 143.626 1.00 58.18  ? 93  THR c O   1 
ATOM 3270 C CB  . THR D 3 94  ? 115.333 115.943 145.160 1.00 58.18  ? 93  THR c CB  1 
ATOM 3271 O OG1 . THR D 3 94  ? 114.459 115.111 145.935 1.00 58.18  ? 93  THR c OG1 1 
ATOM 3272 C CG2 . THR D 3 94  ? 115.258 117.401 145.611 1.00 58.18  ? 93  THR c CG2 1 
ATOM 3273 N N   . PHE D 3 95  ? 112.986 115.336 142.479 1.00 59.07  ? 94  PHE c N   1 
ATOM 3274 C CA  . PHE D 3 95  ? 111.578 115.524 142.168 1.00 59.07  ? 94  PHE c CA  1 
ATOM 3275 C C   . PHE D 3 95  ? 110.722 114.961 143.292 1.00 59.07  ? 94  PHE c C   1 
ATOM 3276 O O   . PHE D 3 95  ? 111.062 113.938 143.890 1.00 59.07  ? 94  PHE c O   1 
ATOM 3277 C CB  . PHE D 3 95  ? 111.218 114.833 140.856 1.00 59.07  ? 94  PHE c CB  1 
ATOM 3278 C CG  . PHE D 3 95  ? 112.082 115.229 139.700 1.00 59.07  ? 94  PHE c CG  1 
ATOM 3279 C CD1 . PHE D 3 95  ? 111.896 116.438 139.063 1.00 59.07  ? 94  PHE c CD1 1 
ATOM 3280 C CD2 . PHE D 3 95  ? 113.072 114.383 139.242 1.00 59.07  ? 94  PHE c CD2 1 
ATOM 3281 C CE1 . PHE D 3 95  ? 112.685 116.799 137.996 1.00 59.07  ? 94  PHE c CE1 1 
ATOM 3282 C CE2 . PHE D 3 95  ? 113.862 114.739 138.175 1.00 59.07  ? 94  PHE c CE2 1 
ATOM 3283 C CZ  . PHE D 3 95  ? 113.670 115.949 137.552 1.00 59.07  ? 94  PHE c CZ  1 
ATOM 3284 N N   . SER D 3 96  ? 109.593 115.614 143.557 1.00 65.16  ? 95  SER c N   1 
ATOM 3285 C CA  . SER D 3 96  ? 108.739 115.289 144.695 1.00 65.16  ? 95  SER c CA  1 
ATOM 3286 C C   . SER D 3 96  ? 107.276 115.203 144.274 1.00 65.16  ? 95  SER c C   1 
ATOM 3287 O O   . SER D 3 96  ? 106.395 115.815 144.880 1.00 65.16  ? 95  SER c O   1 
ATOM 3288 C CB  . SER D 3 96  ? 108.916 116.311 145.811 1.00 65.16  ? 95  SER c CB  1 
ATOM 3289 O OG  . SER D 3 96  ? 108.033 116.048 146.886 1.00 65.16  ? 95  SER c OG  1 
ATOM 3290 N N   . PHE D 3 97  ? 107.000 114.440 143.220 1.00 69.40  ? 96  PHE c N   1 
ATOM 3291 C CA  . PHE D 3 97  ? 105.628 114.273 142.759 1.00 69.40  ? 96  PHE c CA  1 
ATOM 3292 C C   . PHE D 3 97  ? 104.771 113.606 143.829 1.00 69.40  ? 96  PHE c C   1 
ATOM 3293 O O   . PHE D 3 97  ? 105.263 112.849 144.669 1.00 69.40  ? 96  PHE c O   1 
ATOM 3294 C CB  . PHE D 3 97  ? 105.589 113.438 141.483 1.00 69.40  ? 96  PHE c CB  1 
ATOM 3295 C CG  . PHE D 3 97  ? 106.606 113.840 140.465 1.00 69.40  ? 96  PHE c CG  1 
ATOM 3296 C CD1 . PHE D 3 97  ? 106.574 115.100 139.901 1.00 69.40  ? 96  PHE c CD1 1 
ATOM 3297 C CD2 . PHE D 3 97  ? 107.588 112.957 140.065 1.00 69.40  ? 96  PHE c CD2 1 
ATOM 3298 C CE1 . PHE D 3 97  ? 107.506 115.473 138.959 1.00 69.40  ? 96  PHE c CE1 1 
ATOM 3299 C CE2 . PHE D 3 97  ? 108.522 113.324 139.125 1.00 69.40  ? 96  PHE c CE2 1 
ATOM 3300 C CZ  . PHE D 3 97  ? 108.482 114.585 138.571 1.00 69.40  ? 96  PHE c CZ  1 
ATOM 3301 N N   . THR D 3 98  ? 103.475 113.897 143.791 1.00 75.42  ? 97  THR c N   1 
ATOM 3302 C CA  . THR D 3 98  ? 102.515 113.335 144.726 1.00 75.42  ? 97  THR c CA  1 
ATOM 3303 C C   . THR D 3 98  ? 101.841 112.108 144.116 1.00 75.42  ? 97  THR c C   1 
ATOM 3304 O O   . THR D 3 98  ? 102.083 111.736 142.966 1.00 75.42  ? 97  THR c O   1 
ATOM 3305 C CB  . THR D 3 98  ? 101.480 114.385 145.129 1.00 75.42  ? 97  THR c CB  1 
ATOM 3306 O OG1 . THR D 3 98  ? 100.557 113.812 146.062 1.00 75.42  ? 97  THR c OG1 1 
ATOM 3307 C CG2 . THR D 3 98  ? 100.722 114.872 143.911 1.00 75.42  ? 97  THR c CG2 1 
ATOM 3308 N N   . GLN D 3 99  ? 100.976 111.470 144.909 1.00 78.43  ? 98  GLN c N   1 
ATOM 3309 C CA  . GLN D 3 99  ? 100.374 110.207 144.490 1.00 78.43  ? 98  GLN c CA  1 
ATOM 3310 C C   . GLN D 3 99  ? 99.437  110.388 143.303 1.00 78.43  ? 98  GLN c C   1 
ATOM 3311 O O   . GLN D 3 99  ? 99.433  109.566 142.380 1.00 78.43  ? 98  GLN c O   1 
ATOM 3312 C CB  . GLN D 3 99  ? 99.628  109.568 145.658 1.00 78.43  ? 98  GLN c CB  1 
ATOM 3313 C CG  . GLN D 3 99  ? 100.513 108.763 146.586 1.00 78.43  ? 98  GLN c CG  1 
ATOM 3314 C CD  . GLN D 3 99  ? 99.723  108.038 147.653 1.00 78.43  ? 98  GLN c CD  1 
ATOM 3315 O OE1 . GLN D 3 99  ? 100.249 107.167 148.346 1.00 78.43  ? 98  GLN c OE1 1 
ATOM 3316 N NE2 . GLN D 3 99  ? 98.452  108.393 147.794 1.00 78.43  ? 98  GLN c NE2 1 
ATOM 3317 N N   . TYR D 3 100 ? 98.634  111.450 143.305 1.00 77.28  ? 99  TYR c N   1 
ATOM 3318 C CA  . TYR D 3 100 ? 97.594  111.637 142.304 1.00 77.28  ? 99  TYR c CA  1 
ATOM 3319 C C   . TYR D 3 100 ? 98.079  112.395 141.075 1.00 77.28  ? 99  TYR c C   1 
ATOM 3320 O O   . TYR D 3 100 ? 97.267  113.027 140.391 1.00 77.28  ? 99  TYR c O   1 
ATOM 3321 C CB  . TYR D 3 100 ? 96.397  112.363 142.919 1.00 77.28  ? 99  TYR c CB  1 
ATOM 3322 C CG  . TYR D 3 100 ? 95.583  111.514 143.864 1.00 77.28  ? 99  TYR c CG  1 
ATOM 3323 C CD1 . TYR D 3 100 ? 95.937  111.397 145.199 1.00 77.28  ? 99  TYR c CD1 1 
ATOM 3324 C CD2 . TYR D 3 100 ? 94.459  110.835 143.422 1.00 77.28  ? 99  TYR c CD2 1 
ATOM 3325 C CE1 . TYR D 3 100 ? 95.195  110.626 146.067 1.00 77.28  ? 99  TYR c CE1 1 
ATOM 3326 C CE2 . TYR D 3 100 ? 93.711  110.060 144.282 1.00 77.28  ? 99  TYR c CE2 1 
ATOM 3327 C CZ  . TYR D 3 100 ? 94.084  109.959 145.604 1.00 77.28  ? 99  TYR c CZ  1 
ATOM 3328 O OH  . TYR D 3 100 ? 93.342  109.188 146.468 1.00 77.28  ? 99  TYR c OH  1 
ATOM 3329 N N   . SER D 3 101 ? 99.373  112.351 140.778 1.00 78.18  ? 100 SER c N   1 
ATOM 3330 C CA  . SER D 3 101 ? 99.930  113.087 139.651 1.00 78.18  ? 100 SER c CA  1 
ATOM 3331 C C   . SER D 3 101 ? 100.006 112.175 138.434 1.00 78.18  ? 100 SER c C   1 
ATOM 3332 O O   . SER D 3 101 ? 100.673 111.136 138.471 1.00 78.18  ? 100 SER c O   1 
ATOM 3333 C CB  . SER D 3 101 ? 101.314 113.632 139.995 1.00 78.18  ? 100 SER c CB  1 
ATOM 3334 O OG  . SER D 3 101 ? 102.254 112.580 140.099 1.00 78.18  ? 100 SER c OG  1 
ATOM 3335 N N   . THR D 3 102 ? 99.331  112.567 137.357 1.00 81.82  ? 101 THR c N   1 
ATOM 3336 C CA  . THR D 3 102 ? 99.381  111.802 136.123 1.00 81.82  ? 101 THR c CA  1 
ATOM 3337 C C   . THR D 3 102 ? 100.747 111.948 135.460 1.00 81.82  ? 101 THR c C   1 
ATOM 3338 O O   . THR D 3 102 ? 101.537 112.836 135.788 1.00 81.82  ? 101 THR c O   1 
ATOM 3339 C CB  . THR D 3 102 ? 98.285  112.258 135.163 1.00 81.82  ? 101 THR c CB  1 
ATOM 3340 O OG1 . THR D 3 102 ? 98.676  113.488 134.543 1.00 81.82  ? 101 THR c OG1 1 
ATOM 3341 C CG2 . THR D 3 102 ? 96.983  112.468 135.914 1.00 81.82  ? 101 THR c CG2 1 
ATOM 3342 N N   . ASP D 3 103 ? 101.022 111.053 134.508 1.00 80.65  ? 102 ASP c N   1 
ATOM 3343 C CA  . ASP D 3 103 ? 102.336 111.031 133.874 1.00 80.65  ? 102 ASP c CA  1 
ATOM 3344 C C   . ASP D 3 103 ? 102.585 112.269 133.022 1.00 80.65  ? 102 ASP c C   1 
ATOM 3345 O O   . ASP D 3 103 ? 103.741 112.654 132.821 1.00 80.65  ? 102 ASP c O   1 
ATOM 3346 C CB  . ASP D 3 103 ? 102.495 109.767 133.032 1.00 80.65  ? 102 ASP c CB  1 
ATOM 3347 C CG  . ASP D 3 103 ? 101.391 109.605 132.012 1.00 80.65  ? 102 ASP c CG  1 
ATOM 3348 O OD1 . ASP D 3 103 ? 100.439 110.413 132.031 1.00 80.65  ? 102 ASP c OD1 1 
ATOM 3349 O OD2 . ASP D 3 103 ? 101.473 108.667 131.190 1.00 80.65  ? 102 ASP c OD2 1 
ATOM 3350 N N   . GLU D 3 104 ? 101.527 112.898 132.505 1.00 82.61  ? 103 GLU c N   1 
ATOM 3351 C CA  . GLU D 3 104 ? 101.712 114.089 131.683 1.00 82.61  ? 103 GLU c CA  1 
ATOM 3352 C C   . GLU D 3 104 ? 102.332 115.227 132.483 1.00 82.61  ? 103 GLU c C   1 
ATOM 3353 O O   . GLU D 3 104 ? 103.241 115.912 132.001 1.00 82.61  ? 103 GLU c O   1 
ATOM 3354 C CB  . GLU D 3 104 ? 100.378 114.522 131.078 1.00 82.61  ? 103 GLU c CB  1 
ATOM 3355 C CG  . GLU D 3 104 ? 99.803  113.523 130.094 1.00 82.61  ? 103 GLU c CG  1 
ATOM 3356 C CD  . GLU D 3 104 ? 100.662 113.375 128.853 1.00 82.61  ? 103 GLU c CD  1 
ATOM 3357 O OE1 . GLU D 3 104 ? 101.289 114.373 128.441 1.00 82.61  ? 103 GLU c OE1 1 
ATOM 3358 O OE2 . GLU D 3 104 ? 100.710 112.261 128.290 1.00 82.61  ? 103 GLU c OE2 1 
ATOM 3359 N N   . GLU D 3 105 ? 101.859 115.440 133.712 1.00 80.28  ? 104 GLU c N   1 
ATOM 3360 C CA  . GLU D 3 105 ? 102.410 116.503 134.546 1.00 80.28  ? 104 GLU c CA  1 
ATOM 3361 C C   . GLU D 3 105 ? 103.870 116.239 134.893 1.00 80.28  ? 104 GLU c C   1 
ATOM 3362 O O   . GLU D 3 105 ? 104.707 117.151 134.844 1.00 80.28  ? 104 GLU c O   1 
ATOM 3363 C CB  . GLU D 3 105 ? 101.568 116.645 135.812 1.00 80.28  ? 104 GLU c CB  1 
ATOM 3364 C CG  . GLU D 3 105 ? 102.160 117.543 136.874 1.00 80.28  ? 104 GLU c CG  1 
ATOM 3365 C CD  . GLU D 3 105 ? 101.413 117.432 138.186 1.00 80.28  ? 104 GLU c CD  1 
ATOM 3366 O OE1 . GLU D 3 105 ? 100.173 117.290 138.150 1.00 80.28  ? 104 GLU c OE1 1 
ATOM 3367 O OE2 . GLU D 3 105 ? 102.060 117.480 139.251 1.00 80.28  ? 104 GLU c OE2 1 
ATOM 3368 N N   . ARG D 3 106 ? 104.197 114.995 135.245 1.00 73.36  ? 105 ARG c N   1 
ATOM 3369 C CA  . ARG D 3 106 ? 105.576 114.660 135.576 1.00 73.36  ? 105 ARG c CA  1 
ATOM 3370 C C   . ARG D 3 106 ? 106.487 114.824 134.367 1.00 73.36  ? 105 ARG c C   1 
ATOM 3371 O O   . ARG D 3 106 ? 107.612 115.324 134.489 1.00 73.36  ? 105 ARG c O   1 
ATOM 3372 C CB  . ARG D 3 106 ? 105.644 113.238 136.121 1.00 73.36  ? 105 ARG c CB  1 
ATOM 3373 C CG  . ARG D 3 106 ? 104.956 113.078 137.462 1.00 73.36  ? 105 ARG c CG  1 
ATOM 3374 C CD  . ARG D 3 106 ? 105.021 111.650 137.960 1.00 73.36  ? 105 ARG c CD  1 
ATOM 3375 N NE  . ARG D 3 106 ? 104.470 110.700 137.003 1.00 73.36  ? 105 ARG c NE  1 
ATOM 3376 C CZ  . ARG D 3 106 ? 103.508 109.833 137.282 1.00 73.36  ? 105 ARG c CZ  1 
ATOM 3377 N NH1 . ARG D 3 106 ? 102.960 109.774 138.484 1.00 73.36  ? 105 ARG c NH1 1 
ATOM 3378 N NH2 . ARG D 3 106 ? 103.088 109.002 136.335 1.00 73.36  ? 105 ARG c NH2 1 
ATOM 3379 N N   . ALA D 3 107 ? 106.016 114.410 133.190 1.00 73.23  ? 106 ALA c N   1 
ATOM 3380 C CA  . ALA D 3 107 ? 106.798 114.601 131.976 1.00 73.23  ? 106 ALA c CA  1 
ATOM 3381 C C   . ALA D 3 107 ? 106.993 116.080 131.679 1.00 73.23  ? 106 ALA c C   1 
ATOM 3382 O O   . ALA D 3 107 ? 108.065 116.490 131.225 1.00 73.23  ? 106 ALA c O   1 
ATOM 3383 C CB  . ALA D 3 107 ? 106.123 113.901 130.799 1.00 73.23  ? 106 ALA c CB  1 
ATOM 3384 N N   . PHE D 3 108 ? 105.965 116.896 131.917 1.00 71.44  ? 107 PHE c N   1 
ATOM 3385 C CA  . PHE D 3 108 ? 106.111 118.334 131.723 1.00 71.44  ? 107 PHE c CA  1 
ATOM 3386 C C   . PHE D 3 108 ? 107.177 118.905 132.646 1.00 71.44  ? 107 PHE c C   1 
ATOM 3387 O O   . PHE D 3 108 ? 108.009 119.717 132.220 1.00 71.44  ? 107 PHE c O   1 
ATOM 3388 C CB  . PHE D 3 108 ? 104.772 119.033 131.953 1.00 71.44  ? 107 PHE c CB  1 
ATOM 3389 C CG  . PHE D 3 108 ? 104.759 120.471 131.531 1.00 71.44  ? 107 PHE c CG  1 
ATOM 3390 C CD1 . PHE D 3 108 ? 105.229 121.460 132.374 1.00 71.44  ? 107 PHE c CD1 1 
ATOM 3391 C CD2 . PHE D 3 108 ? 104.280 120.833 130.287 1.00 71.44  ? 107 PHE c CD2 1 
ATOM 3392 C CE1 . PHE D 3 108 ? 105.218 122.781 131.985 1.00 71.44  ? 107 PHE c CE1 1 
ATOM 3393 C CE2 . PHE D 3 108 ? 104.267 122.153 129.893 1.00 71.44  ? 107 PHE c CE2 1 
ATOM 3394 C CZ  . PHE D 3 108 ? 104.736 123.127 130.742 1.00 71.44  ? 107 PHE c CZ  1 
ATOM 3395 N N   . VAL D 3 109 ? 107.168 118.494 133.915 1.00 70.60  ? 108 VAL c N   1 
ATOM 3396 C CA  . VAL D 3 109 ? 108.179 118.974 134.854 1.00 70.60  ? 108 VAL c CA  1 
ATOM 3397 C C   . VAL D 3 109 ? 109.571 118.569 134.390 1.00 70.60  ? 108 VAL c C   1 
ATOM 3398 O O   . VAL D 3 109 ? 110.501 119.388 134.367 1.00 70.60  ? 108 VAL c O   1 
ATOM 3399 C CB  . VAL D 3 109 ? 107.890 118.451 136.271 1.00 70.60  ? 108 VAL c CB  1 
ATOM 3400 C CG1 . VAL D 3 109 ? 109.022 118.818 137.208 1.00 70.60  ? 108 VAL c CG1 1 
ATOM 3401 C CG2 . VAL D 3 109 ? 106.575 119.001 136.779 1.00 70.60  ? 108 VAL c CG2 1 
ATOM 3402 N N   . ARG D 3 110 ? 109.732 117.304 133.997 1.00 68.51  ? 109 ARG c N   1 
ATOM 3403 C CA  . ARG D 3 110 ? 111.043 116.823 133.575 1.00 68.51  ? 109 ARG c CA  1 
ATOM 3404 C C   . ARG D 3 110 ? 111.529 117.564 132.336 1.00 68.51  ? 109 ARG c C   1 
ATOM 3405 O O   . ARG D 3 110 ? 112.695 117.967 132.259 1.00 68.51  ? 109 ARG c O   1 
ATOM 3406 C CB  . ARG D 3 110 ? 110.993 115.319 133.317 1.00 68.51  ? 109 ARG c CB  1 
ATOM 3407 C CG  . ARG D 3 110 ? 112.259 114.770 132.697 1.00 68.51  ? 109 ARG c CG  1 
ATOM 3408 C CD  . ARG D 3 110 ? 112.051 113.375 132.146 1.00 68.51  ? 109 ARG c CD  1 
ATOM 3409 N NE  . ARG D 3 110 ? 110.995 113.326 131.143 1.00 68.51  ? 109 ARG c NE  1 
ATOM 3410 C CZ  . ARG D 3 110 ? 111.188 113.521 129.847 1.00 68.51  ? 109 ARG c CZ  1 
ATOM 3411 N NH1 . ARG D 3 110 ? 112.383 113.811 129.362 1.00 68.51  ? 109 ARG c NH1 1 
ATOM 3412 N NH2 . ARG D 3 110 ? 110.154 113.425 129.016 1.00 68.51  ? 109 ARG c NH2 1 
ATOM 3413 N N   . THR D 3 111 ? 110.646 117.761 131.355 1.00 70.35  ? 110 THR c N   1 
ATOM 3414 C CA  . THR D 3 111 ? 111.049 118.439 130.129 1.00 70.35  ? 110 THR c CA  1 
ATOM 3415 C C   . THR D 3 111 ? 111.384 119.904 130.366 1.00 70.35  ? 110 THR c C   1 
ATOM 3416 O O   . THR D 3 111 ? 112.348 120.411 129.780 1.00 70.35  ? 110 THR c O   1 
ATOM 3417 C CB  . THR D 3 111 ? 109.962 118.314 129.065 1.00 70.35  ? 110 THR c CB  1 
ATOM 3418 O OG1 . THR D 3 111 ? 108.711 118.759 129.601 1.00 70.35  ? 110 THR c OG1 1 
ATOM 3419 C CG2 . THR D 3 111 ? 109.836 116.877 128.597 1.00 70.35  ? 110 THR c CG2 1 
ATOM 3420 N N   . GLU D 3 112 ? 110.613 120.611 131.199 1.00 73.09  ? 111 GLU c N   1 
ATOM 3421 C CA  . GLU D 3 112 ? 110.945 122.012 131.435 1.00 73.09  ? 111 GLU c CA  1 
ATOM 3422 C C   . GLU D 3 112 ? 112.241 122.136 132.222 1.00 73.09  ? 111 GLU c C   1 
ATOM 3423 O O   . GLU D 3 112 ? 113.017 123.071 132.000 1.00 73.09  ? 111 GLU c O   1 
ATOM 3424 C CB  . GLU D 3 112 ? 109.812 122.751 132.149 1.00 73.09  ? 111 GLU c CB  1 
ATOM 3425 C CG  . GLU D 3 112 ? 109.529 122.313 133.567 1.00 73.09  ? 111 GLU c CG  1 
ATOM 3426 C CD  . GLU D 3 112 ? 108.386 123.093 134.187 1.00 73.09  ? 111 GLU c CD  1 
ATOM 3427 O OE1 . GLU D 3 112 ? 107.825 123.972 133.500 1.00 73.09  ? 111 GLU c OE1 1 
ATOM 3428 O OE2 . GLU D 3 112 ? 108.048 122.832 135.360 1.00 73.09  ? 111 GLU c OE2 1 
ATOM 3429 N N   . LEU D 3 113 ? 112.506 121.201 133.138 1.00 65.39  ? 112 LEU c N   1 
ATOM 3430 C CA  . LEU D 3 113 ? 113.797 121.219 133.816 1.00 65.39  ? 112 LEU c CA  1 
ATOM 3431 C C   . LEU D 3 113 ? 114.934 120.943 132.841 1.00 65.39  ? 112 LEU c C   1 
ATOM 3432 O O   . LEU D 3 113 ? 115.993 121.574 132.922 1.00 65.39  ? 112 LEU c O   1 
ATOM 3433 C CB  . LEU D 3 113 ? 113.817 120.208 134.959 1.00 65.39  ? 112 LEU c CB  1 
ATOM 3434 C CG  . LEU D 3 113 ? 115.140 120.157 135.723 1.00 65.39  ? 112 LEU c CG  1 
ATOM 3435 C CD1 . LEU D 3 113 ? 115.486 121.527 136.273 1.00 65.39  ? 112 LEU c CD1 1 
ATOM 3436 C CD2 . LEU D 3 113 ? 115.081 119.138 136.841 1.00 65.39  ? 112 LEU c CD2 1 
ATOM 3437 N N   . ALA D 3 114 ? 114.736 120.001 131.916 1.00 65.48  ? 113 ALA c N   1 
ATOM 3438 C CA  . ALA D 3 114 ? 115.790 119.669 130.962 1.00 65.48  ? 113 ALA c CA  1 
ATOM 3439 C C   . ALA D 3 114 ? 116.080 120.831 130.022 1.00 65.48  ? 113 ALA c C   1 
ATOM 3440 O O   . ALA D 3 114 ? 117.245 121.123 129.732 1.00 65.48  ? 113 ALA c O   1 
ATOM 3441 C CB  . ALA D 3 114 ? 115.405 118.424 130.167 1.00 65.48  ? 113 ALA c CB  1 
ATOM 3442 N N   . ALA D 3 115 ? 115.042 121.501 129.530 1.00 64.61  ? 114 ALA c N   1 
ATOM 3443 C CA  . ALA D 3 115 ? 115.232 122.614 128.611 1.00 64.61  ? 114 ALA c CA  1 
ATOM 3444 C C   . ALA D 3 115 ? 115.580 123.917 129.313 1.00 64.61  ? 114 ALA c C   1 
ATOM 3445 O O   . ALA D 3 115 ? 116.017 124.861 128.648 1.00 64.61  ? 114 ALA c O   1 
ATOM 3446 C CB  . ALA D 3 115 ? 113.982 122.820 127.756 1.00 64.61  ? 114 ALA c CB  1 
ATOM 3447 N N   . LEU D 3 116 ? 115.392 123.998 130.627 1.00 64.65  ? 115 LEU c N   1 
ATOM 3448 C CA  . LEU D 3 116 ? 115.795 125.175 131.381 1.00 64.65  ? 115 LEU c CA  1 
ATOM 3449 C C   . LEU D 3 116 ? 117.289 125.208 131.659 1.00 64.65  ? 115 LEU c C   1 
ATOM 3450 O O   . LEU D 3 116 ? 117.829 126.280 131.949 1.00 64.65  ? 115 LEU c O   1 
ATOM 3451 C CB  . LEU D 3 116 ? 115.025 125.235 132.702 1.00 64.65  ? 115 LEU c CB  1 
ATOM 3452 C CG  . LEU D 3 116 ? 115.049 126.549 133.476 1.00 64.65  ? 115 LEU c CG  1 
ATOM 3453 C CD1 . LEU D 3 116 ? 114.431 127.660 132.649 1.00 64.65  ? 115 LEU c CD1 1 
ATOM 3454 C CD2 . LEU D 3 116 ? 114.317 126.385 134.792 1.00 64.65  ? 115 LEU c CD2 1 
ATOM 3455 N N   . LEU D 3 117 ? 117.967 124.067 131.566 1.00 65.00  ? 116 LEU c N   1 
ATOM 3456 C CA  . LEU D 3 117 ? 119.408 124.003 131.760 1.00 65.00  ? 116 LEU c CA  1 
ATOM 3457 C C   . LEU D 3 117 ? 120.186 124.326 130.494 1.00 65.00  ? 116 LEU c C   1 
ATOM 3458 O O   . LEU D 3 117 ? 121.420 124.302 130.522 1.00 65.00  ? 116 LEU c O   1 
ATOM 3459 C CB  . LEU D 3 117 ? 119.810 122.618 132.271 1.00 65.00  ? 116 LEU c CB  1 
ATOM 3460 C CG  . LEU D 3 117 ? 119.448 122.311 133.723 1.00 65.00  ? 116 LEU c CG  1 
ATOM 3461 C CD1 . LEU D 3 117 ? 120.100 121.020 134.173 1.00 65.00  ? 116 LEU c CD1 1 
ATOM 3462 C CD2 . LEU D 3 117 ? 119.857 123.456 134.626 1.00 65.00  ? 116 LEU c CD2 1 
ATOM 3463 N N   . ALA D 3 118 ? 119.501 124.610 129.389 1.00 67.22  ? 117 ALA c N   1 
ATOM 3464 C CA  . ALA D 3 118 ? 120.149 125.035 128.159 1.00 67.22  ? 117 ALA c CA  1 
ATOM 3465 C C   . ALA D 3 118 ? 119.750 126.441 127.739 1.00 67.22  ? 117 ALA c C   1 
ATOM 3466 O O   . ALA D 3 118 ? 120.277 126.945 126.740 1.00 67.22  ? 117 ALA c O   1 
ATOM 3467 C CB  . ALA D 3 118 ? 119.840 124.053 127.022 1.00 67.22  ? 117 ALA c CB  1 
ATOM 3468 N N   . SER D 3 119 ? 118.841 127.086 128.465 1.00 70.91  ? 118 SER c N   1 
ATOM 3469 C CA  . SER D 3 119 ? 118.439 128.442 128.144 1.00 70.91  ? 118 SER c CA  1 
ATOM 3470 C C   . SER D 3 119 ? 119.585 129.410 128.427 1.00 70.91  ? 118 SER c C   1 
ATOM 3471 O O   . SER D 3 119 ? 120.475 129.115 129.227 1.00 70.91  ? 118 SER c O   1 
ATOM 3472 C CB  . SER D 3 119 ? 117.206 128.833 128.953 1.00 70.91  ? 118 SER c CB  1 
ATOM 3473 O OG  . SER D 3 119 ? 117.507 128.895 130.334 1.00 70.91  ? 118 SER c OG  1 
ATOM 3474 N N   . PRO D 3 120 ? 119.587 130.575 127.775 1.00 77.15  ? 119 PRO c N   1 
ATOM 3475 C CA  . PRO D 3 120 ? 120.690 131.527 127.982 1.00 77.15  ? 119 PRO c CA  1 
ATOM 3476 C C   . PRO D 3 120 ? 120.850 131.987 129.419 1.00 77.15  ? 119 PRO c C   1 
ATOM 3477 O O   . PRO D 3 120 ? 121.956 132.390 129.799 1.00 77.15  ? 119 PRO c O   1 
ATOM 3478 C CB  . PRO D 3 120 ? 120.321 132.695 127.059 1.00 77.15  ? 119 PRO c CB  1 
ATOM 3479 C CG  . PRO D 3 120 ? 119.468 132.082 126.009 1.00 77.15  ? 119 PRO c CG  1 
ATOM 3480 C CD  . PRO D 3 120 ? 118.676 131.018 126.706 1.00 77.15  ? 119 PRO c CD  1 
ATOM 3481 N N   . LEU D 3 121 ? 119.790 131.957 130.227 1.00 75.96  ? 120 LEU c N   1 
ATOM 3482 C CA  . LEU D 3 121 ? 119.915 132.384 131.617 1.00 75.96  ? 120 LEU c CA  1 
ATOM 3483 C C   . LEU D 3 121 ? 120.789 131.427 132.420 1.00 75.96  ? 120 LEU c C   1 
ATOM 3484 O O   . LEU D 3 121 ? 121.745 131.850 133.081 1.00 75.96  ? 120 LEU c O   1 
ATOM 3485 C CB  . LEU D 3 121 ? 118.533 132.505 132.254 1.00 75.96  ? 120 LEU c CB  1 
ATOM 3486 C CG  . LEU D 3 121 ? 118.545 132.889 133.733 1.00 75.96  ? 120 LEU c CG  1 
ATOM 3487 C CD1 . LEU D 3 121 ? 119.217 134.236 133.930 1.00 75.96  ? 120 LEU c CD1 1 
ATOM 3488 C CD2 . LEU D 3 121 ? 117.134 132.903 134.292 1.00 75.96  ? 120 LEU c CD2 1 
ATOM 3489 N N   . LEU D 3 122 ? 120.486 130.130 132.366 1.00 72.63  ? 121 LEU c N   1 
ATOM 3490 C CA  . LEU D 3 122 ? 121.206 129.162 133.183 1.00 72.63  ? 121 LEU c CA  1 
ATOM 3491 C C   . LEU D 3 122 ? 122.602 128.862 132.659 1.00 72.63  ? 121 LEU c C   1 
ATOM 3492 O O   . LEU D 3 122 ? 123.530 128.723 133.463 1.00 72.63  ? 121 LEU c O   1 
ATOM 3493 C CB  . LEU D 3 122 ? 120.412 127.862 133.296 1.00 72.63  ? 121 LEU c CB  1 
ATOM 3494 C CG  . LEU D 3 122 ? 119.446 127.755 134.477 1.00 72.63  ? 121 LEU c CG  1 
ATOM 3495 C CD1 . LEU D 3 122 ? 120.216 127.785 135.781 1.00 72.63  ? 121 LEU c CD1 1 
ATOM 3496 C CD2 . LEU D 3 122 ? 118.399 128.857 134.449 1.00 72.63  ? 121 LEU c CD2 1 
ATOM 3497 N N   . ILE D 3 123 ? 122.780 128.765 131.337 1.00 74.07  ? 122 ILE c N   1 
ATOM 3498 C CA  . ILE D 3 123 ? 124.108 128.494 130.792 1.00 74.07  ? 122 ILE c CA  1 
ATOM 3499 C C   . ILE D 3 123 ? 125.085 129.615 131.089 1.00 74.07  ? 122 ILE c C   1 
ATOM 3500 O O   . ILE D 3 123 ? 126.296 129.432 130.920 1.00 74.07  ? 122 ILE c O   1 
ATOM 3501 C CB  . ILE D 3 123 ? 124.094 128.280 129.267 1.00 74.07  ? 122 ILE c CB  1 
ATOM 3502 C CG1 . ILE D 3 123 ? 123.616 129.540 128.554 1.00 74.07  ? 122 ILE c CG1 1 
ATOM 3503 C CG2 . ILE D 3 123 ? 123.191 127.124 128.906 1.00 74.07  ? 122 ILE c CG2 1 
ATOM 3504 C CD1 . ILE D 3 123 ? 123.794 129.490 127.052 1.00 74.07  ? 122 ILE c CD1 1 
ATOM 3505 N N   . ASP D 3 124 ? 124.591 130.771 131.517 1.00 76.72  ? 123 ASP c N   1 
ATOM 3506 C CA  . ASP D 3 124 ? 125.422 131.886 131.939 1.00 76.72  ? 123 ASP c CA  1 
ATOM 3507 C C   . ASP D 3 124 ? 125.550 131.942 133.452 1.00 76.72  ? 123 ASP c C   1 
ATOM 3508 O O   . ASP D 3 124 ? 126.659 132.095 133.967 1.00 76.72  ? 123 ASP c O   1 
ATOM 3509 C CB  . ASP D 3 124 ? 124.826 133.197 131.395 1.00 76.72  ? 123 ASP c CB  1 
ATOM 3510 C CG  . ASP D 3 124 ? 125.399 134.457 132.044 1.00 76.72  ? 123 ASP c CG  1 
ATOM 3511 O OD1 . ASP D 3 124 ? 126.436 134.413 132.732 1.00 76.72  ? 123 ASP c OD1 1 
ATOM 3512 O OD2 . ASP D 3 124 ? 124.847 135.541 131.766 1.00 76.72  ? 123 ASP c OD2 1 
ATOM 3513 N N   . ALA D 3 125 ? 124.447 131.769 134.184 1.00 75.80  ? 124 ALA c N   1 
ATOM 3514 C CA  . ALA D 3 125 ? 124.497 131.794 135.640 1.00 75.80  ? 124 ALA c CA  1 
ATOM 3515 C C   . ALA D 3 125 ? 125.234 130.604 136.238 1.00 75.80  ? 124 ALA c C   1 
ATOM 3516 O O   . ALA D 3 125 ? 125.558 130.641 137.429 1.00 75.80  ? 124 ALA c O   1 
ATOM 3517 C CB  . ALA D 3 125 ? 123.081 131.855 136.214 1.00 75.80  ? 124 ALA c CB  1 
ATOM 3518 N N   . ILE D 3 126 ? 125.499 129.553 135.464 1.00 74.21  ? 125 ILE c N   1 
ATOM 3519 C CA  . ILE D 3 126 ? 126.240 128.398 135.947 1.00 74.21  ? 125 ILE c CA  1 
ATOM 3520 C C   . ILE D 3 126 ? 127.698 128.437 135.506 1.00 74.21  ? 125 ILE c C   1 
ATOM 3521 O O   . ILE D 3 126 ? 128.589 128.069 136.273 1.00 74.21  ? 125 ILE c O   1 
ATOM 3522 C CB  . ILE D 3 126 ? 125.566 127.084 135.499 1.00 74.21  ? 125 ILE c CB  1 
ATOM 3523 C CG1 . ILE D 3 126 ? 124.171 126.968 136.104 1.00 74.21  ? 125 ILE c CG1 1 
ATOM 3524 C CG2 . ILE D 3 126 ? 126.396 125.890 135.921 1.00 74.21  ? 125 ILE c CG2 1 
ATOM 3525 C CD1 . ILE D 3 126 ? 123.352 125.849 135.514 1.00 74.21  ? 125 ILE c CD1 1 
ATOM 3526 N N   . ASP D 3 127 ? 127.964 128.874 134.275 1.00 78.51  ? 126 ASP c N   1 
ATOM 3527 C CA  . ASP D 3 127 ? 129.335 128.876 133.775 1.00 78.51  ? 126 ASP c CA  1 
ATOM 3528 C C   . ASP D 3 127 ? 130.189 129.913 134.496 1.00 78.51  ? 126 ASP c C   1 
ATOM 3529 O O   . ASP D 3 127 ? 131.308 129.614 134.929 1.00 78.51  ? 126 ASP c O   1 
ATOM 3530 C CB  . ASP D 3 127 ? 129.346 129.130 132.269 1.00 78.51  ? 126 ASP c CB  1 
ATOM 3531 C CG  . ASP D 3 127 ? 129.344 127.849 131.465 1.00 78.51  ? 126 ASP c CG  1 
ATOM 3532 O OD1 . ASP D 3 127 ? 129.359 126.761 132.076 1.00 78.51  ? 126 ASP c OD1 1 
ATOM 3533 O OD2 . ASP D 3 127 ? 129.337 127.930 130.219 1.00 78.51  ? 126 ASP c OD2 1 
ATOM 3534 N N   . GLN D 3 128 ? 129.685 131.138 134.630 1.00 81.34  ? 127 GLN c N   1 
ATOM 3535 C CA  . GLN D 3 128 ? 130.444 132.227 135.228 1.00 81.34  ? 127 GLN c CA  1 
ATOM 3536 C C   . GLN D 3 128 ? 129.980 132.590 136.631 1.00 81.34  ? 127 GLN c C   1 
ATOM 3537 O O   . GLN D 3 128 ? 130.545 133.509 137.233 1.00 81.34  ? 127 GLN c O   1 
ATOM 3538 C CB  . GLN D 3 128 ? 130.385 133.467 134.330 1.00 81.34  ? 127 GLN c CB  1 
ATOM 3539 C CG  . GLN D 3 128 ? 131.093 133.296 132.998 1.00 81.34  ? 127 GLN c CG  1 
ATOM 3540 C CD  . GLN D 3 128 ? 130.242 132.580 131.974 1.00 81.34  ? 127 GLN c CD  1 
ATOM 3541 O OE1 . GLN D 3 128 ? 129.026 132.480 132.125 1.00 81.34  ? 127 GLN c OE1 1 
ATOM 3542 N NE2 . GLN D 3 128 ? 130.877 132.071 130.926 1.00 81.34  ? 127 GLN c NE2 1 
ATOM 3543 N N   . LEU D 3 129 ? 128.966 131.905 137.160 1.00 75.72  ? 128 LEU c N   1 
ATOM 3544 C CA  . LEU D 3 129 ? 128.497 132.095 138.534 1.00 75.72  ? 128 LEU c CA  1 
ATOM 3545 C C   . LEU D 3 129 ? 127.978 133.509 138.779 1.00 75.72  ? 128 LEU c C   1 
ATOM 3546 O O   . LEU D 3 129 ? 127.978 133.990 139.914 1.00 75.72  ? 128 LEU c O   1 
ATOM 3547 C CB  . LEU D 3 129 ? 129.589 131.758 139.553 1.00 75.72  ? 128 LEU c CB  1 
ATOM 3548 C CG  . LEU D 3 129 ? 129.801 130.296 139.953 1.00 75.72  ? 128 LEU c CG  1 
ATOM 3549 C CD1 . LEU D 3 129 ? 128.565 129.743 140.642 1.00 75.72  ? 128 LEU c CD1 1 
ATOM 3550 C CD2 . LEU D 3 129 ? 130.191 129.443 138.767 1.00 75.72  ? 128 LEU c CD2 1 
ATOM 3551 N N   . ASN D 3 130 ? 127.532 134.190 137.734 1.00 79.60  ? 129 ASN c N   1 
ATOM 3552 C CA  . ASN D 3 130 ? 127.005 135.529 137.974 1.00 79.60  ? 129 ASN c CA  1 
ATOM 3553 C C   . ASN D 3 130 ? 125.538 135.451 138.378 1.00 79.60  ? 129 ASN c C   1 
ATOM 3554 O O   . ASN D 3 130 ? 124.730 134.877 137.641 1.00 79.60  ? 129 ASN c O   1 
ATOM 3555 C CB  . ASN D 3 130 ? 127.158 136.408 136.740 1.00 79.60  ? 129 ASN c CB  1 
ATOM 3556 C CG  . ASN D 3 130 ? 126.729 135.711 135.472 1.00 79.60  ? 129 ASN c CG  1 
ATOM 3557 O OD1 . ASN D 3 130 ? 126.340 134.545 135.493 1.00 79.60  ? 129 ASN c OD1 1 
ATOM 3558 N ND2 . ASN D 3 130 ? 126.796 136.422 134.354 1.00 79.60  ? 129 ASN c ND2 1 
ATOM 3559 N N   . PRO D 3 131 ? 125.164 135.994 139.532 1.00 80.86  ? 130 PRO c N   1 
ATOM 3560 C CA  . PRO D 3 131 ? 123.756 135.960 139.938 1.00 80.86  ? 130 PRO c CA  1 
ATOM 3561 C C   . PRO D 3 131 ? 122.863 136.711 138.968 1.00 80.86  ? 130 PRO c C   1 
ATOM 3562 O O   . PRO D 3 131 ? 123.246 137.730 138.390 1.00 80.86  ? 130 PRO c O   1 
ATOM 3563 C CB  . PRO D 3 131 ? 123.767 136.633 141.316 1.00 80.86  ? 130 PRO c CB  1 
ATOM 3564 C CG  . PRO D 3 131 ? 125.020 137.435 141.340 1.00 80.86  ? 130 PRO c CG  1 
ATOM 3565 C CD  . PRO D 3 131 ? 126.011 136.653 140.537 1.00 80.86  ? 130 PRO c CD  1 
ATOM 3566 N N   . ALA D 3 132 ? 121.657 136.183 138.789 1.00 85.97  ? 131 ALA c N   1 
ATOM 3567 C CA  . ALA D 3 132 ? 120.652 136.876 137.998 1.00 85.97  ? 131 ALA c CA  1 
ATOM 3568 C C   . ALA D 3 132 ? 120.120 138.068 138.781 1.00 85.97  ? 131 ALA c C   1 
ATOM 3569 O O   . ALA D 3 132 ? 119.820 137.957 139.973 1.00 85.97  ? 131 ALA c O   1 
ATOM 3570 C CB  . ALA D 3 132 ? 119.517 135.925 137.630 1.00 85.97  ? 131 ALA c CB  1 
ATOM 3571 N N   . TYR D 3 133 ? 120.006 139.209 138.113 1.00 94.70  ? 132 TYR c N   1 
ATOM 3572 C CA  . TYR D 3 133 ? 119.559 140.429 138.770 1.00 94.70  ? 132 TYR c CA  1 
ATOM 3573 C C   . TYR D 3 133 ? 118.458 141.118 137.973 1.00 94.70  ? 132 TYR c C   1 
ATOM 3574 O O   . TYR D 3 133 ? 118.157 142.289 138.199 1.00 94.70  ? 132 TYR c O   1 
ATOM 3575 C CB  . TYR D 3 133 ? 120.733 141.386 138.977 1.00 94.70  ? 132 TYR c CB  1 
ATOM 3576 C CG  . TYR D 3 133 ? 121.458 141.756 137.702 1.00 94.70  ? 132 TYR c CG  1 
ATOM 3577 C CD1 . TYR D 3 133 ? 122.449 140.936 137.180 1.00 94.70  ? 132 TYR c CD1 1 
ATOM 3578 C CD2 . TYR D 3 133 ? 121.156 142.928 137.025 1.00 94.70  ? 132 TYR c CD2 1 
ATOM 3579 C CE1 . TYR D 3 133 ? 123.114 141.270 136.019 1.00 94.70  ? 132 TYR c CE1 1 
ATOM 3580 C CE2 . TYR D 3 133 ? 121.817 143.271 135.864 1.00 94.70  ? 132 TYR c CE2 1 
ATOM 3581 C CZ  . TYR D 3 133 ? 122.795 142.438 135.365 1.00 94.70  ? 132 TYR c CZ  1 
ATOM 3582 O OH  . TYR D 3 133 ? 123.457 142.773 134.208 1.00 94.70  ? 132 TYR c OH  1 
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