data_8W5N
# 
_entry.id   8W5N 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8W5N         pdb_00008w5n 10.2210/pdb8w5n/pdb 
WWPDB D_1300040610 ?            ?                   
EMDB  EMD-37298    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-02-26 ? 
2 'EM metadata'     1 0 2025-02-26 ? 
3 'Half map'        1 0 2025-02-26 1 
4 'Half map'        1 0 2025-02-26 2 
5 Image             1 0 2025-02-26 ? 
6 'Primary map'     1 0 2025-02-26 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Half map'        repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 Image             repository 'Initial release' ? ? 
6 6 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8W5N 
_pdbx_database_status.recvd_initial_deposition_date   2023-08-27 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure of Qb-Ab21' 
_pdbx_database_related.db_id          EMD-37298 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              zhup@ibp.ac.cn 
_pdbx_contact_author.name_first         Ping 
_pdbx_contact_author.name_last          Zhu 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-2648-3170 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Bao, K.Y.' 1 ? 
'Li, R.H.'  2 ? 
'Hua, Z.L.' 3 ? 
'Hou, B.D.' 4 ? 
'Zhu, P.'   5 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Cell Rep' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2211-1247 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            44 
_citation.language                  ? 
_citation.page_first                115334 
_citation.page_last                 115334 
_citation.title                     
'Competition propels, rather than limits, the success of low-affinity B cells in the germinal center response.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.celrep.2025.115334 
_citation.pdbx_database_id_PubMed   39955776 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Li, R.'  1 ? 
primary 'Bao, K.' 2 ? 
primary 'Liu, C.' 3 ? 
primary 'Ma, X.'  4 ? 
primary 'Hua, Z.' 5 ? 
primary 'Zhu, P.' 6 ? 
primary 'Hou, B.' 7 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'Minor capsid protein A1' 14268.071 3 ? ? ? ? 
2 polymer man 'Heavy chain of Ab21'     13729.213 1 ? ? ? ? 
3 polymer man 'Light chain of Ab21'     12406.779 1 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Qb coat protein' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;MAKLETVTLGNIGKDGKQTLVLNPRGVNPTNGVASLSQAGAVPALEKRVTVSVSQPSRNRKNYKVQVKIQNPTACTANGS
CDPSVTRQAYADVTFSFTQYSTDEERAFVRTELAALLASPLLIDAIDQLNPAY
;
;MAKLETVTLGNIGKDGKQTLVLNPRGVNPTNGVASLSQAGAVPALEKRVTVSVSQPSRNRKNYKVQVKIQNPTACTANGS
CDPSVTRQAYADVTFSFTQYSTDEERAFVRTELAALLASPLLIDAIDQLNPAY
;
A,B,C ? 
2 'polypeptide(L)' no no 
;VHSEVQLVESGGGLVKSGGSLKLSCAASGFTFSSYAMSWVRQTPEKRLEWVATISDGGRYIYYSDNVEGRFTISRDNAKN
NLYLQMSHLKSEDTAIYHCARDSSGYFPYFSYWGQGTLVTVSAA
;
;VHSEVQLVESGGGLVKSGGSLKLSCAASGFTFSSYAMSWVRQTPEKRLEWVATISDGGRYIYYSDNVEGRFTISRDNAKN
NLYLQMSHLKSEDTAIYHCARDSSGYFPYFSYWGQGTLVTVSAA
;
H     ? 
3 'polypeptide(L)' no no 
;VHSNIVLTQSPASLAVSLGQRATISCRASESVDHSGNNFIHWYQQKPGQPPKLLIYLASHLESGVPARFSGSGSRTDFTL
TIDPVEADDFATYYCQQNNEVPLTFGAGTKLEIK
;
;VHSNIVLTQSPASLAVSLGQRATISCRASESVDHSGNNFIHWYQQKPGQPPKLLIYLASHLESGVPARFSGSGSRTDFTL
TIDPVEADDFATYYCQQNNEVPLTFGAGTKLEIK
;
L     ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ALA n 
1 3   LYS n 
1 4   LEU n 
1 5   GLU n 
1 6   THR n 
1 7   VAL n 
1 8   THR n 
1 9   LEU n 
1 10  GLY n 
1 11  ASN n 
1 12  ILE n 
1 13  GLY n 
1 14  LYS n 
1 15  ASP n 
1 16  GLY n 
1 17  LYS n 
1 18  GLN n 
1 19  THR n 
1 20  LEU n 
1 21  VAL n 
1 22  LEU n 
1 23  ASN n 
1 24  PRO n 
1 25  ARG n 
1 26  GLY n 
1 27  VAL n 
1 28  ASN n 
1 29  PRO n 
1 30  THR n 
1 31  ASN n 
1 32  GLY n 
1 33  VAL n 
1 34  ALA n 
1 35  SER n 
1 36  LEU n 
1 37  SER n 
1 38  GLN n 
1 39  ALA n 
1 40  GLY n 
1 41  ALA n 
1 42  VAL n 
1 43  PRO n 
1 44  ALA n 
1 45  LEU n 
1 46  GLU n 
1 47  LYS n 
1 48  ARG n 
1 49  VAL n 
1 50  THR n 
1 51  VAL n 
1 52  SER n 
1 53  VAL n 
1 54  SER n 
1 55  GLN n 
1 56  PRO n 
1 57  SER n 
1 58  ARG n 
1 59  ASN n 
1 60  ARG n 
1 61  LYS n 
1 62  ASN n 
1 63  TYR n 
1 64  LYS n 
1 65  VAL n 
1 66  GLN n 
1 67  VAL n 
1 68  LYS n 
1 69  ILE n 
1 70  GLN n 
1 71  ASN n 
1 72  PRO n 
1 73  THR n 
1 74  ALA n 
1 75  CYS n 
1 76  THR n 
1 77  ALA n 
1 78  ASN n 
1 79  GLY n 
1 80  SER n 
1 81  CYS n 
1 82  ASP n 
1 83  PRO n 
1 84  SER n 
1 85  VAL n 
1 86  THR n 
1 87  ARG n 
1 88  GLN n 
1 89  ALA n 
1 90  TYR n 
1 91  ALA n 
1 92  ASP n 
1 93  VAL n 
1 94  THR n 
1 95  PHE n 
1 96  SER n 
1 97  PHE n 
1 98  THR n 
1 99  GLN n 
1 100 TYR n 
1 101 SER n 
1 102 THR n 
1 103 ASP n 
1 104 GLU n 
1 105 GLU n 
1 106 ARG n 
1 107 ALA n 
1 108 PHE n 
1 109 VAL n 
1 110 ARG n 
1 111 THR n 
1 112 GLU n 
1 113 LEU n 
1 114 ALA n 
1 115 ALA n 
1 116 LEU n 
1 117 LEU n 
1 118 ALA n 
1 119 SER n 
1 120 PRO n 
1 121 LEU n 
1 122 LEU n 
1 123 ILE n 
1 124 ASP n 
1 125 ALA n 
1 126 ILE n 
1 127 ASP n 
1 128 GLN n 
1 129 LEU n 
1 130 ASN n 
1 131 PRO n 
1 132 ALA n 
1 133 TYR n 
2 1   VAL n 
2 2   HIS n 
2 3   SER n 
2 4   GLU n 
2 5   VAL n 
2 6   GLN n 
2 7   LEU n 
2 8   VAL n 
2 9   GLU n 
2 10  SER n 
2 11  GLY n 
2 12  GLY n 
2 13  GLY n 
2 14  LEU n 
2 15  VAL n 
2 16  LYS n 
2 17  SER n 
2 18  GLY n 
2 19  GLY n 
2 20  SER n 
2 21  LEU n 
2 22  LYS n 
2 23  LEU n 
2 24  SER n 
2 25  CYS n 
2 26  ALA n 
2 27  ALA n 
2 28  SER n 
2 29  GLY n 
2 30  PHE n 
2 31  THR n 
2 32  PHE n 
2 33  SER n 
2 34  SER n 
2 35  TYR n 
2 36  ALA n 
2 37  MET n 
2 38  SER n 
2 39  TRP n 
2 40  VAL n 
2 41  ARG n 
2 42  GLN n 
2 43  THR n 
2 44  PRO n 
2 45  GLU n 
2 46  LYS n 
2 47  ARG n 
2 48  LEU n 
2 49  GLU n 
2 50  TRP n 
2 51  VAL n 
2 52  ALA n 
2 53  THR n 
2 54  ILE n 
2 55  SER n 
2 56  ASP n 
2 57  GLY n 
2 58  GLY n 
2 59  ARG n 
2 60  TYR n 
2 61  ILE n 
2 62  TYR n 
2 63  TYR n 
2 64  SER n 
2 65  ASP n 
2 66  ASN n 
2 67  VAL n 
2 68  GLU n 
2 69  GLY n 
2 70  ARG n 
2 71  PHE n 
2 72  THR n 
2 73  ILE n 
2 74  SER n 
2 75  ARG n 
2 76  ASP n 
2 77  ASN n 
2 78  ALA n 
2 79  LYS n 
2 80  ASN n 
2 81  ASN n 
2 82  LEU n 
2 83  TYR n 
2 84  LEU n 
2 85  GLN n 
2 86  MET n 
2 87  SER n 
2 88  HIS n 
2 89  LEU n 
2 90  LYS n 
2 91  SER n 
2 92  GLU n 
2 93  ASP n 
2 94  THR n 
2 95  ALA n 
2 96  ILE n 
2 97  TYR n 
2 98  HIS n 
2 99  CYS n 
2 100 ALA n 
2 101 ARG n 
2 102 ASP n 
2 103 SER n 
2 104 SER n 
2 105 GLY n 
2 106 TYR n 
2 107 PHE n 
2 108 PRO n 
2 109 TYR n 
2 110 PHE n 
2 111 SER n 
2 112 TYR n 
2 113 TRP n 
2 114 GLY n 
2 115 GLN n 
2 116 GLY n 
2 117 THR n 
2 118 LEU n 
2 119 VAL n 
2 120 THR n 
2 121 VAL n 
2 122 SER n 
2 123 ALA n 
2 124 ALA n 
3 1   VAL n 
3 2   HIS n 
3 3   SER n 
3 4   ASN n 
3 5   ILE n 
3 6   VAL n 
3 7   LEU n 
3 8   THR n 
3 9   GLN n 
3 10  SER n 
3 11  PRO n 
3 12  ALA n 
3 13  SER n 
3 14  LEU n 
3 15  ALA n 
3 16  VAL n 
3 17  SER n 
3 18  LEU n 
3 19  GLY n 
3 20  GLN n 
3 21  ARG n 
3 22  ALA n 
3 23  THR n 
3 24  ILE n 
3 25  SER n 
3 26  CYS n 
3 27  ARG n 
3 28  ALA n 
3 29  SER n 
3 30  GLU n 
3 31  SER n 
3 32  VAL n 
3 33  ASP n 
3 34  HIS n 
3 35  SER n 
3 36  GLY n 
3 37  ASN n 
3 38  ASN n 
3 39  PHE n 
3 40  ILE n 
3 41  HIS n 
3 42  TRP n 
3 43  TYR n 
3 44  GLN n 
3 45  GLN n 
3 46  LYS n 
3 47  PRO n 
3 48  GLY n 
3 49  GLN n 
3 50  PRO n 
3 51  PRO n 
3 52  LYS n 
3 53  LEU n 
3 54  LEU n 
3 55  ILE n 
3 56  TYR n 
3 57  LEU n 
3 58  ALA n 
3 59  SER n 
3 60  HIS n 
3 61  LEU n 
3 62  GLU n 
3 63  SER n 
3 64  GLY n 
3 65  VAL n 
3 66  PRO n 
3 67  ALA n 
3 68  ARG n 
3 69  PHE n 
3 70  SER n 
3 71  GLY n 
3 72  SER n 
3 73  GLY n 
3 74  SER n 
3 75  ARG n 
3 76  THR n 
3 77  ASP n 
3 78  PHE n 
3 79  THR n 
3 80  LEU n 
3 81  THR n 
3 82  ILE n 
3 83  ASP n 
3 84  PRO n 
3 85  VAL n 
3 86  GLU n 
3 87  ALA n 
3 88  ASP n 
3 89  ASP n 
3 90  PHE n 
3 91  ALA n 
3 92  THR n 
3 93  TYR n 
3 94  TYR n 
3 95  CYS n 
3 96  GLN n 
3 97  GLN n 
3 98  ASN n 
3 99  ASN n 
3 100 GLU n 
3 101 VAL n 
3 102 PRO n 
3 103 LEU n 
3 104 THR n 
3 105 PHE n 
3 106 GLY n 
3 107 ALA n 
3 108 GLY n 
3 109 THR n 
3 110 LYS n 
3 111 LEU n 
3 112 GLU n 
3 113 ILE n 
3 114 LYS n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 133 ? ? ? ? ? ? ? ? ? 'Escherichia phage Qbeta' 2789016 ? ? ? ? ? ? ? ? 'Escherichia coli' 562  
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 124 ? ? ? ? ? ? ? ? ? 'Mus musculus'            10090   ? ? ? ? ? ? ? ? 'Homo sapiens'     9606 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 114 ? ? ? ? ? ? ? ? ? 'Mus musculus'            10090   ? ? ? ? ? ? ? ? 'Homo sapiens'     9606 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   0   ?   ?   ?   A . n 
A 1 2   ALA 2   1   1   ALA ALA A . n 
A 1 3   LYS 3   2   2   LYS LYS A . n 
A 1 4   LEU 4   3   3   LEU LEU A . n 
A 1 5   GLU 5   4   4   GLU GLU A . n 
A 1 6   THR 6   5   5   THR THR A . n 
A 1 7   VAL 7   6   6   VAL VAL A . n 
A 1 8   THR 8   7   7   THR THR A . n 
A 1 9   LEU 9   8   8   LEU LEU A . n 
A 1 10  GLY 10  9   9   GLY GLY A . n 
A 1 11  ASN 11  10  10  ASN ASN A . n 
A 1 12  ILE 12  11  11  ILE ILE A . n 
A 1 13  GLY 13  12  12  GLY GLY A . n 
A 1 14  LYS 14  13  13  LYS LYS A . n 
A 1 15  ASP 15  14  14  ASP ASP A . n 
A 1 16  GLY 16  15  15  GLY GLY A . n 
A 1 17  LYS 17  16  16  LYS LYS A . n 
A 1 18  GLN 18  17  17  GLN GLN A . n 
A 1 19  THR 19  18  18  THR THR A . n 
A 1 20  LEU 20  19  19  LEU LEU A . n 
A 1 21  VAL 21  20  20  VAL VAL A . n 
A 1 22  LEU 22  21  21  LEU LEU A . n 
A 1 23  ASN 23  22  22  ASN ASN A . n 
A 1 24  PRO 24  23  23  PRO PRO A . n 
A 1 25  ARG 25  24  24  ARG ARG A . n 
A 1 26  GLY 26  25  25  GLY GLY A . n 
A 1 27  VAL 27  26  26  VAL VAL A . n 
A 1 28  ASN 28  27  27  ASN ASN A . n 
A 1 29  PRO 29  28  28  PRO PRO A . n 
A 1 30  THR 30  29  29  THR THR A . n 
A 1 31  ASN 31  30  30  ASN ASN A . n 
A 1 32  GLY 32  31  31  GLY GLY A . n 
A 1 33  VAL 33  32  32  VAL VAL A . n 
A 1 34  ALA 34  33  33  ALA ALA A . n 
A 1 35  SER 35  34  34  SER SER A . n 
A 1 36  LEU 36  35  35  LEU LEU A . n 
A 1 37  SER 37  36  36  SER SER A . n 
A 1 38  GLN 38  37  37  GLN GLN A . n 
A 1 39  ALA 39  38  38  ALA ALA A . n 
A 1 40  GLY 40  39  39  GLY GLY A . n 
A 1 41  ALA 41  40  40  ALA ALA A . n 
A 1 42  VAL 42  41  41  VAL VAL A . n 
A 1 43  PRO 43  42  42  PRO PRO A . n 
A 1 44  ALA 44  43  43  ALA ALA A . n 
A 1 45  LEU 45  44  44  LEU LEU A . n 
A 1 46  GLU 46  45  45  GLU GLU A . n 
A 1 47  LYS 47  46  46  LYS LYS A . n 
A 1 48  ARG 48  47  47  ARG ARG A . n 
A 1 49  VAL 49  48  48  VAL VAL A . n 
A 1 50  THR 50  49  49  THR THR A . n 
A 1 51  VAL 51  50  50  VAL VAL A . n 
A 1 52  SER 52  51  51  SER SER A . n 
A 1 53  VAL 53  52  52  VAL VAL A . n 
A 1 54  SER 54  53  53  SER SER A . n 
A 1 55  GLN 55  54  54  GLN GLN A . n 
A 1 56  PRO 56  55  55  PRO PRO A . n 
A 1 57  SER 57  56  56  SER SER A . n 
A 1 58  ARG 58  57  57  ARG ARG A . n 
A 1 59  ASN 59  58  58  ASN ASN A . n 
A 1 60  ARG 60  59  59  ARG ARG A . n 
A 1 61  LYS 61  60  60  LYS LYS A . n 
A 1 62  ASN 62  61  61  ASN ASN A . n 
A 1 63  TYR 63  62  62  TYR TYR A . n 
A 1 64  LYS 64  63  63  LYS LYS A . n 
A 1 65  VAL 65  64  64  VAL VAL A . n 
A 1 66  GLN 66  65  65  GLN GLN A . n 
A 1 67  VAL 67  66  66  VAL VAL A . n 
A 1 68  LYS 68  67  67  LYS LYS A . n 
A 1 69  ILE 69  68  68  ILE ILE A . n 
A 1 70  GLN 70  69  69  GLN GLN A . n 
A 1 71  ASN 71  70  70  ASN ASN A . n 
A 1 72  PRO 72  71  71  PRO PRO A . n 
A 1 73  THR 73  72  72  THR THR A . n 
A 1 74  ALA 74  73  73  ALA ALA A . n 
A 1 75  CYS 75  74  74  CYS CYS A . n 
A 1 76  THR 76  75  75  THR THR A . n 
A 1 77  ALA 77  76  76  ALA ALA A . n 
A 1 78  ASN 78  77  77  ASN ASN A . n 
A 1 79  GLY 79  78  78  GLY GLY A . n 
A 1 80  SER 80  79  79  SER SER A . n 
A 1 81  CYS 81  80  80  CYS CYS A . n 
A 1 82  ASP 82  81  81  ASP ASP A . n 
A 1 83  PRO 83  82  82  PRO PRO A . n 
A 1 84  SER 84  83  83  SER SER A . n 
A 1 85  VAL 85  84  84  VAL VAL A . n 
A 1 86  THR 86  85  85  THR THR A . n 
A 1 87  ARG 87  86  86  ARG ARG A . n 
A 1 88  GLN 88  87  87  GLN GLN A . n 
A 1 89  ALA 89  88  88  ALA ALA A . n 
A 1 90  TYR 90  89  89  TYR TYR A . n 
A 1 91  ALA 91  90  90  ALA ALA A . n 
A 1 92  ASP 92  91  91  ASP ASP A . n 
A 1 93  VAL 93  92  92  VAL VAL A . n 
A 1 94  THR 94  93  93  THR THR A . n 
A 1 95  PHE 95  94  94  PHE PHE A . n 
A 1 96  SER 96  95  95  SER SER A . n 
A 1 97  PHE 97  96  96  PHE PHE A . n 
A 1 98  THR 98  97  97  THR THR A . n 
A 1 99  GLN 99  98  98  GLN GLN A . n 
A 1 100 TYR 100 99  99  TYR TYR A . n 
A 1 101 SER 101 100 100 SER SER A . n 
A 1 102 THR 102 101 101 THR THR A . n 
A 1 103 ASP 103 102 102 ASP ASP A . n 
A 1 104 GLU 104 103 103 GLU GLU A . n 
A 1 105 GLU 105 104 104 GLU GLU A . n 
A 1 106 ARG 106 105 105 ARG ARG A . n 
A 1 107 ALA 107 106 106 ALA ALA A . n 
A 1 108 PHE 108 107 107 PHE PHE A . n 
A 1 109 VAL 109 108 108 VAL VAL A . n 
A 1 110 ARG 110 109 109 ARG ARG A . n 
A 1 111 THR 111 110 110 THR THR A . n 
A 1 112 GLU 112 111 111 GLU GLU A . n 
A 1 113 LEU 113 112 112 LEU LEU A . n 
A 1 114 ALA 114 113 113 ALA ALA A . n 
A 1 115 ALA 115 114 114 ALA ALA A . n 
A 1 116 LEU 116 115 115 LEU LEU A . n 
A 1 117 LEU 117 116 116 LEU LEU A . n 
A 1 118 ALA 118 117 117 ALA ALA A . n 
A 1 119 SER 119 118 118 SER SER A . n 
A 1 120 PRO 120 119 119 PRO PRO A . n 
A 1 121 LEU 121 120 120 LEU LEU A . n 
A 1 122 LEU 122 121 121 LEU LEU A . n 
A 1 123 ILE 123 122 122 ILE ILE A . n 
A 1 124 ASP 124 123 123 ASP ASP A . n 
A 1 125 ALA 125 124 124 ALA ALA A . n 
A 1 126 ILE 126 125 125 ILE ILE A . n 
A 1 127 ASP 127 126 126 ASP ASP A . n 
A 1 128 GLN 128 127 127 GLN GLN A . n 
A 1 129 LEU 129 128 128 LEU LEU A . n 
A 1 130 ASN 130 129 129 ASN ASN A . n 
A 1 131 PRO 131 130 130 PRO PRO A . n 
A 1 132 ALA 132 131 131 ALA ALA A . n 
A 1 133 TYR 133 132 132 TYR TYR A . n 
B 1 1   MET 1   0   ?   ?   ?   B . n 
B 1 2   ALA 2   1   1   ALA ALA B . n 
B 1 3   LYS 3   2   2   LYS LYS B . n 
B 1 4   LEU 4   3   3   LEU LEU B . n 
B 1 5   GLU 5   4   4   GLU GLU B . n 
B 1 6   THR 6   5   5   THR THR B . n 
B 1 7   VAL 7   6   6   VAL VAL B . n 
B 1 8   THR 8   7   7   THR THR B . n 
B 1 9   LEU 9   8   8   LEU LEU B . n 
B 1 10  GLY 10  9   9   GLY GLY B . n 
B 1 11  ASN 11  10  10  ASN ASN B . n 
B 1 12  ILE 12  11  11  ILE ILE B . n 
B 1 13  GLY 13  12  12  GLY GLY B . n 
B 1 14  LYS 14  13  13  LYS LYS B . n 
B 1 15  ASP 15  14  14  ASP ASP B . n 
B 1 16  GLY 16  15  15  GLY GLY B . n 
B 1 17  LYS 17  16  16  LYS LYS B . n 
B 1 18  GLN 18  17  17  GLN GLN B . n 
B 1 19  THR 19  18  18  THR THR B . n 
B 1 20  LEU 20  19  19  LEU LEU B . n 
B 1 21  VAL 21  20  20  VAL VAL B . n 
B 1 22  LEU 22  21  21  LEU LEU B . n 
B 1 23  ASN 23  22  22  ASN ASN B . n 
B 1 24  PRO 24  23  23  PRO PRO B . n 
B 1 25  ARG 25  24  24  ARG ARG B . n 
B 1 26  GLY 26  25  25  GLY GLY B . n 
B 1 27  VAL 27  26  26  VAL VAL B . n 
B 1 28  ASN 28  27  27  ASN ASN B . n 
B 1 29  PRO 29  28  28  PRO PRO B . n 
B 1 30  THR 30  29  29  THR THR B . n 
B 1 31  ASN 31  30  30  ASN ASN B . n 
B 1 32  GLY 32  31  31  GLY GLY B . n 
B 1 33  VAL 33  32  32  VAL VAL B . n 
B 1 34  ALA 34  33  33  ALA ALA B . n 
B 1 35  SER 35  34  34  SER SER B . n 
B 1 36  LEU 36  35  35  LEU LEU B . n 
B 1 37  SER 37  36  36  SER SER B . n 
B 1 38  GLN 38  37  37  GLN GLN B . n 
B 1 39  ALA 39  38  38  ALA ALA B . n 
B 1 40  GLY 40  39  39  GLY GLY B . n 
B 1 41  ALA 41  40  40  ALA ALA B . n 
B 1 42  VAL 42  41  41  VAL VAL B . n 
B 1 43  PRO 43  42  42  PRO PRO B . n 
B 1 44  ALA 44  43  43  ALA ALA B . n 
B 1 45  LEU 45  44  44  LEU LEU B . n 
B 1 46  GLU 46  45  45  GLU GLU B . n 
B 1 47  LYS 47  46  46  LYS LYS B . n 
B 1 48  ARG 48  47  47  ARG ARG B . n 
B 1 49  VAL 49  48  48  VAL VAL B . n 
B 1 50  THR 50  49  49  THR THR B . n 
B 1 51  VAL 51  50  50  VAL VAL B . n 
B 1 52  SER 52  51  51  SER SER B . n 
B 1 53  VAL 53  52  52  VAL VAL B . n 
B 1 54  SER 54  53  53  SER SER B . n 
B 1 55  GLN 55  54  54  GLN GLN B . n 
B 1 56  PRO 56  55  55  PRO PRO B . n 
B 1 57  SER 57  56  56  SER SER B . n 
B 1 58  ARG 58  57  57  ARG ARG B . n 
B 1 59  ASN 59  58  58  ASN ASN B . n 
B 1 60  ARG 60  59  59  ARG ARG B . n 
B 1 61  LYS 61  60  60  LYS LYS B . n 
B 1 62  ASN 62  61  61  ASN ASN B . n 
B 1 63  TYR 63  62  62  TYR TYR B . n 
B 1 64  LYS 64  63  63  LYS LYS B . n 
B 1 65  VAL 65  64  64  VAL VAL B . n 
B 1 66  GLN 66  65  65  GLN GLN B . n 
B 1 67  VAL 67  66  66  VAL VAL B . n 
B 1 68  LYS 68  67  67  LYS LYS B . n 
B 1 69  ILE 69  68  68  ILE ILE B . n 
B 1 70  GLN 70  69  69  GLN GLN B . n 
B 1 71  ASN 71  70  70  ASN ASN B . n 
B 1 72  PRO 72  71  71  PRO PRO B . n 
B 1 73  THR 73  72  72  THR THR B . n 
B 1 74  ALA 74  73  73  ALA ALA B . n 
B 1 75  CYS 75  74  74  CYS CYS B . n 
B 1 76  THR 76  75  75  THR THR B . n 
B 1 77  ALA 77  76  76  ALA ALA B . n 
B 1 78  ASN 78  77  77  ASN ASN B . n 
B 1 79  GLY 79  78  78  GLY GLY B . n 
B 1 80  SER 80  79  79  SER SER B . n 
B 1 81  CYS 81  80  80  CYS CYS B . n 
B 1 82  ASP 82  81  81  ASP ASP B . n 
B 1 83  PRO 83  82  82  PRO PRO B . n 
B 1 84  SER 84  83  83  SER SER B . n 
B 1 85  VAL 85  84  84  VAL VAL B . n 
B 1 86  THR 86  85  85  THR THR B . n 
B 1 87  ARG 87  86  86  ARG ARG B . n 
B 1 88  GLN 88  87  87  GLN GLN B . n 
B 1 89  ALA 89  88  88  ALA ALA B . n 
B 1 90  TYR 90  89  89  TYR TYR B . n 
B 1 91  ALA 91  90  90  ALA ALA B . n 
B 1 92  ASP 92  91  91  ASP ASP B . n 
B 1 93  VAL 93  92  92  VAL VAL B . n 
B 1 94  THR 94  93  93  THR THR B . n 
B 1 95  PHE 95  94  94  PHE PHE B . n 
B 1 96  SER 96  95  95  SER SER B . n 
B 1 97  PHE 97  96  96  PHE PHE B . n 
B 1 98  THR 98  97  97  THR THR B . n 
B 1 99  GLN 99  98  98  GLN GLN B . n 
B 1 100 TYR 100 99  99  TYR TYR B . n 
B 1 101 SER 101 100 100 SER SER B . n 
B 1 102 THR 102 101 101 THR THR B . n 
B 1 103 ASP 103 102 102 ASP ASP B . n 
B 1 104 GLU 104 103 103 GLU GLU B . n 
B 1 105 GLU 105 104 104 GLU GLU B . n 
B 1 106 ARG 106 105 105 ARG ARG B . n 
B 1 107 ALA 107 106 106 ALA ALA B . n 
B 1 108 PHE 108 107 107 PHE PHE B . n 
B 1 109 VAL 109 108 108 VAL VAL B . n 
B 1 110 ARG 110 109 109 ARG ARG B . n 
B 1 111 THR 111 110 110 THR THR B . n 
B 1 112 GLU 112 111 111 GLU GLU B . n 
B 1 113 LEU 113 112 112 LEU LEU B . n 
B 1 114 ALA 114 113 113 ALA ALA B . n 
B 1 115 ALA 115 114 114 ALA ALA B . n 
B 1 116 LEU 116 115 115 LEU LEU B . n 
B 1 117 LEU 117 116 116 LEU LEU B . n 
B 1 118 ALA 118 117 117 ALA ALA B . n 
B 1 119 SER 119 118 118 SER SER B . n 
B 1 120 PRO 120 119 119 PRO PRO B . n 
B 1 121 LEU 121 120 120 LEU LEU B . n 
B 1 122 LEU 122 121 121 LEU LEU B . n 
B 1 123 ILE 123 122 122 ILE ILE B . n 
B 1 124 ASP 124 123 123 ASP ASP B . n 
B 1 125 ALA 125 124 124 ALA ALA B . n 
B 1 126 ILE 126 125 125 ILE ILE B . n 
B 1 127 ASP 127 126 126 ASP ASP B . n 
B 1 128 GLN 128 127 127 GLN GLN B . n 
B 1 129 LEU 129 128 128 LEU LEU B . n 
B 1 130 ASN 130 129 129 ASN ASN B . n 
B 1 131 PRO 131 130 130 PRO PRO B . n 
B 1 132 ALA 132 131 131 ALA ALA B . n 
B 1 133 TYR 133 132 132 TYR TYR B . n 
C 1 1   MET 1   0   ?   ?   ?   C . n 
C 1 2   ALA 2   1   1   ALA ALA C . n 
C 1 3   LYS 3   2   2   LYS LYS C . n 
C 1 4   LEU 4   3   3   LEU LEU C . n 
C 1 5   GLU 5   4   4   GLU GLU C . n 
C 1 6   THR 6   5   5   THR THR C . n 
C 1 7   VAL 7   6   6   VAL VAL C . n 
C 1 8   THR 8   7   7   THR THR C . n 
C 1 9   LEU 9   8   8   LEU LEU C . n 
C 1 10  GLY 10  9   9   GLY GLY C . n 
C 1 11  ASN 11  10  10  ASN ASN C . n 
C 1 12  ILE 12  11  11  ILE ILE C . n 
C 1 13  GLY 13  12  12  GLY GLY C . n 
C 1 14  LYS 14  13  13  LYS LYS C . n 
C 1 15  ASP 15  14  14  ASP ASP C . n 
C 1 16  GLY 16  15  15  GLY GLY C . n 
C 1 17  LYS 17  16  16  LYS LYS C . n 
C 1 18  GLN 18  17  17  GLN GLN C . n 
C 1 19  THR 19  18  18  THR THR C . n 
C 1 20  LEU 20  19  19  LEU LEU C . n 
C 1 21  VAL 21  20  20  VAL VAL C . n 
C 1 22  LEU 22  21  21  LEU LEU C . n 
C 1 23  ASN 23  22  22  ASN ASN C . n 
C 1 24  PRO 24  23  23  PRO PRO C . n 
C 1 25  ARG 25  24  24  ARG ARG C . n 
C 1 26  GLY 26  25  25  GLY GLY C . n 
C 1 27  VAL 27  26  26  VAL VAL C . n 
C 1 28  ASN 28  27  27  ASN ASN C . n 
C 1 29  PRO 29  28  28  PRO PRO C . n 
C 1 30  THR 30  29  29  THR THR C . n 
C 1 31  ASN 31  30  30  ASN ASN C . n 
C 1 32  GLY 32  31  31  GLY GLY C . n 
C 1 33  VAL 33  32  32  VAL VAL C . n 
C 1 34  ALA 34  33  33  ALA ALA C . n 
C 1 35  SER 35  34  34  SER SER C . n 
C 1 36  LEU 36  35  35  LEU LEU C . n 
C 1 37  SER 37  36  36  SER SER C . n 
C 1 38  GLN 38  37  37  GLN GLN C . n 
C 1 39  ALA 39  38  38  ALA ALA C . n 
C 1 40  GLY 40  39  39  GLY GLY C . n 
C 1 41  ALA 41  40  40  ALA ALA C . n 
C 1 42  VAL 42  41  41  VAL VAL C . n 
C 1 43  PRO 43  42  42  PRO PRO C . n 
C 1 44  ALA 44  43  43  ALA ALA C . n 
C 1 45  LEU 45  44  44  LEU LEU C . n 
C 1 46  GLU 46  45  45  GLU GLU C . n 
C 1 47  LYS 47  46  46  LYS LYS C . n 
C 1 48  ARG 48  47  47  ARG ARG C . n 
C 1 49  VAL 49  48  48  VAL VAL C . n 
C 1 50  THR 50  49  49  THR THR C . n 
C 1 51  VAL 51  50  50  VAL VAL C . n 
C 1 52  SER 52  51  51  SER SER C . n 
C 1 53  VAL 53  52  52  VAL VAL C . n 
C 1 54  SER 54  53  53  SER SER C . n 
C 1 55  GLN 55  54  54  GLN GLN C . n 
C 1 56  PRO 56  55  55  PRO PRO C . n 
C 1 57  SER 57  56  56  SER SER C . n 
C 1 58  ARG 58  57  57  ARG ARG C . n 
C 1 59  ASN 59  58  58  ASN ASN C . n 
C 1 60  ARG 60  59  59  ARG ARG C . n 
C 1 61  LYS 61  60  60  LYS LYS C . n 
C 1 62  ASN 62  61  61  ASN ASN C . n 
C 1 63  TYR 63  62  62  TYR TYR C . n 
C 1 64  LYS 64  63  63  LYS LYS C . n 
C 1 65  VAL 65  64  64  VAL VAL C . n 
C 1 66  GLN 66  65  65  GLN GLN C . n 
C 1 67  VAL 67  66  66  VAL VAL C . n 
C 1 68  LYS 68  67  67  LYS LYS C . n 
C 1 69  ILE 69  68  68  ILE ILE C . n 
C 1 70  GLN 70  69  69  GLN GLN C . n 
C 1 71  ASN 71  70  70  ASN ASN C . n 
C 1 72  PRO 72  71  71  PRO PRO C . n 
C 1 73  THR 73  72  72  THR THR C . n 
C 1 74  ALA 74  73  73  ALA ALA C . n 
C 1 75  CYS 75  74  74  CYS CYS C . n 
C 1 76  THR 76  75  75  THR THR C . n 
C 1 77  ALA 77  76  76  ALA ALA C . n 
C 1 78  ASN 78  77  77  ASN ASN C . n 
C 1 79  GLY 79  78  78  GLY GLY C . n 
C 1 80  SER 80  79  79  SER SER C . n 
C 1 81  CYS 81  80  80  CYS CYS C . n 
C 1 82  ASP 82  81  81  ASP ASP C . n 
C 1 83  PRO 83  82  82  PRO PRO C . n 
C 1 84  SER 84  83  83  SER SER C . n 
C 1 85  VAL 85  84  84  VAL VAL C . n 
C 1 86  THR 86  85  85  THR THR C . n 
C 1 87  ARG 87  86  86  ARG ARG C . n 
C 1 88  GLN 88  87  87  GLN GLN C . n 
C 1 89  ALA 89  88  88  ALA ALA C . n 
C 1 90  TYR 90  89  89  TYR TYR C . n 
C 1 91  ALA 91  90  90  ALA ALA C . n 
C 1 92  ASP 92  91  91  ASP ASP C . n 
C 1 93  VAL 93  92  92  VAL VAL C . n 
C 1 94  THR 94  93  93  THR THR C . n 
C 1 95  PHE 95  94  94  PHE PHE C . n 
C 1 96  SER 96  95  95  SER SER C . n 
C 1 97  PHE 97  96  96  PHE PHE C . n 
C 1 98  THR 98  97  97  THR THR C . n 
C 1 99  GLN 99  98  98  GLN GLN C . n 
C 1 100 TYR 100 99  99  TYR TYR C . n 
C 1 101 SER 101 100 100 SER SER C . n 
C 1 102 THR 102 101 101 THR THR C . n 
C 1 103 ASP 103 102 102 ASP ASP C . n 
C 1 104 GLU 104 103 103 GLU GLU C . n 
C 1 105 GLU 105 104 104 GLU GLU C . n 
C 1 106 ARG 106 105 105 ARG ARG C . n 
C 1 107 ALA 107 106 106 ALA ALA C . n 
C 1 108 PHE 108 107 107 PHE PHE C . n 
C 1 109 VAL 109 108 108 VAL VAL C . n 
C 1 110 ARG 110 109 109 ARG ARG C . n 
C 1 111 THR 111 110 110 THR THR C . n 
C 1 112 GLU 112 111 111 GLU GLU C . n 
C 1 113 LEU 113 112 112 LEU LEU C . n 
C 1 114 ALA 114 113 113 ALA ALA C . n 
C 1 115 ALA 115 114 114 ALA ALA C . n 
C 1 116 LEU 116 115 115 LEU LEU C . n 
C 1 117 LEU 117 116 116 LEU LEU C . n 
C 1 118 ALA 118 117 117 ALA ALA C . n 
C 1 119 SER 119 118 118 SER SER C . n 
C 1 120 PRO 120 119 119 PRO PRO C . n 
C 1 121 LEU 121 120 120 LEU LEU C . n 
C 1 122 LEU 122 121 121 LEU LEU C . n 
C 1 123 ILE 123 122 122 ILE ILE C . n 
C 1 124 ASP 124 123 123 ASP ASP C . n 
C 1 125 ALA 125 124 124 ALA ALA C . n 
C 1 126 ILE 126 125 125 ILE ILE C . n 
C 1 127 ASP 127 126 126 ASP ASP C . n 
C 1 128 GLN 128 127 127 GLN GLN C . n 
C 1 129 LEU 129 128 128 LEU LEU C . n 
C 1 130 ASN 130 129 129 ASN ASN C . n 
C 1 131 PRO 131 130 130 PRO PRO C . n 
C 1 132 ALA 132 131 131 ALA ALA C . n 
C 1 133 TYR 133 132 132 TYR TYR C . n 
D 2 1   VAL 1   1   ?   ?   ?   H . n 
D 2 2   HIS 2   2   ?   ?   ?   H . n 
D 2 3   SER 3   3   ?   ?   ?   H . n 
D 2 4   GLU 4   4   4   GLU GLU H . n 
D 2 5   VAL 5   5   5   VAL VAL H . n 
D 2 6   GLN 6   6   6   GLN GLN H . n 
D 2 7   LEU 7   7   7   LEU LEU H . n 
D 2 8   VAL 8   8   8   VAL VAL H . n 
D 2 9   GLU 9   9   9   GLU GLU H . n 
D 2 10  SER 10  10  10  SER SER H . n 
D 2 11  GLY 11  11  11  GLY GLY H . n 
D 2 12  GLY 12  12  12  GLY GLY H . n 
D 2 13  GLY 13  13  13  GLY GLY H . n 
D 2 14  LEU 14  14  14  LEU LEU H . n 
D 2 15  VAL 15  15  15  VAL VAL H . n 
D 2 16  LYS 16  16  16  LYS LYS H . n 
D 2 17  SER 17  17  17  SER SER H . n 
D 2 18  GLY 18  18  18  GLY GLY H . n 
D 2 19  GLY 19  19  19  GLY GLY H . n 
D 2 20  SER 20  20  20  SER SER H . n 
D 2 21  LEU 21  21  21  LEU LEU H . n 
D 2 22  LYS 22  22  22  LYS LYS H . n 
D 2 23  LEU 23  23  23  LEU LEU H . n 
D 2 24  SER 24  24  24  SER SER H . n 
D 2 25  CYS 25  25  25  CYS CYS H . n 
D 2 26  ALA 26  26  26  ALA ALA H . n 
D 2 27  ALA 27  27  27  ALA ALA H . n 
D 2 28  SER 28  28  28  SER SER H . n 
D 2 29  GLY 29  29  29  GLY GLY H . n 
D 2 30  PHE 30  30  30  PHE PHE H . n 
D 2 31  THR 31  31  31  THR THR H . n 
D 2 32  PHE 32  32  32  PHE PHE H . n 
D 2 33  SER 33  33  33  SER SER H . n 
D 2 34  SER 34  34  34  SER SER H . n 
D 2 35  TYR 35  35  35  TYR TYR H . n 
D 2 36  ALA 36  36  36  ALA ALA H . n 
D 2 37  MET 37  37  37  MET MET H . n 
D 2 38  SER 38  38  38  SER SER H . n 
D 2 39  TRP 39  39  39  TRP TRP H . n 
D 2 40  VAL 40  40  40  VAL VAL H . n 
D 2 41  ARG 41  41  41  ARG ARG H . n 
D 2 42  GLN 42  42  42  GLN GLN H . n 
D 2 43  THR 43  43  43  THR THR H . n 
D 2 44  PRO 44  44  44  PRO PRO H . n 
D 2 45  GLU 45  45  45  GLU GLU H . n 
D 2 46  LYS 46  46  46  LYS LYS H . n 
D 2 47  ARG 47  47  47  ARG ARG H . n 
D 2 48  LEU 48  48  48  LEU LEU H . n 
D 2 49  GLU 49  49  49  GLU GLU H . n 
D 2 50  TRP 50  50  50  TRP TRP H . n 
D 2 51  VAL 51  51  51  VAL VAL H . n 
D 2 52  ALA 52  52  52  ALA ALA H . n 
D 2 53  THR 53  53  53  THR THR H . n 
D 2 54  ILE 54  54  54  ILE ILE H . n 
D 2 55  SER 55  55  55  SER SER H . n 
D 2 56  ASP 56  56  56  ASP ASP H . n 
D 2 57  GLY 57  57  57  GLY GLY H . n 
D 2 58  GLY 58  58  58  GLY GLY H . n 
D 2 59  ARG 59  59  59  ARG ARG H . n 
D 2 60  TYR 60  60  60  TYR TYR H . n 
D 2 61  ILE 61  61  61  ILE ILE H . n 
D 2 62  TYR 62  62  62  TYR TYR H . n 
D 2 63  TYR 63  63  63  TYR TYR H . n 
D 2 64  SER 64  64  64  SER SER H . n 
D 2 65  ASP 65  65  65  ASP ASP H . n 
D 2 66  ASN 66  66  66  ASN ASN H . n 
D 2 67  VAL 67  67  67  VAL VAL H . n 
D 2 68  GLU 68  68  68  GLU GLU H . n 
D 2 69  GLY 69  69  69  GLY GLY H . n 
D 2 70  ARG 70  70  70  ARG ARG H . n 
D 2 71  PHE 71  71  71  PHE PHE H . n 
D 2 72  THR 72  72  72  THR THR H . n 
D 2 73  ILE 73  73  73  ILE ILE H . n 
D 2 74  SER 74  74  74  SER SER H . n 
D 2 75  ARG 75  75  75  ARG ARG H . n 
D 2 76  ASP 76  76  76  ASP ASP H . n 
D 2 77  ASN 77  77  77  ASN ASN H . n 
D 2 78  ALA 78  78  78  ALA ALA H . n 
D 2 79  LYS 79  79  79  LYS LYS H . n 
D 2 80  ASN 80  80  80  ASN ASN H . n 
D 2 81  ASN 81  81  81  ASN ASN H . n 
D 2 82  LEU 82  82  82  LEU LEU H . n 
D 2 83  TYR 83  83  83  TYR TYR H . n 
D 2 84  LEU 84  84  84  LEU LEU H . n 
D 2 85  GLN 85  85  85  GLN GLN H . n 
D 2 86  MET 86  86  86  MET MET H . n 
D 2 87  SER 87  87  87  SER SER H . n 
D 2 88  HIS 88  88  88  HIS HIS H . n 
D 2 89  LEU 89  89  89  LEU LEU H . n 
D 2 90  LYS 90  90  90  LYS LYS H . n 
D 2 91  SER 91  91  91  SER SER H . n 
D 2 92  GLU 92  92  92  GLU GLU H . n 
D 2 93  ASP 93  93  93  ASP ASP H . n 
D 2 94  THR 94  94  94  THR THR H . n 
D 2 95  ALA 95  95  95  ALA ALA H . n 
D 2 96  ILE 96  96  96  ILE ILE H . n 
D 2 97  TYR 97  97  97  TYR TYR H . n 
D 2 98  HIS 98  98  98  HIS HIS H . n 
D 2 99  CYS 99  99  99  CYS CYS H . n 
D 2 100 ALA 100 100 100 ALA ALA H . n 
D 2 101 ARG 101 101 101 ARG ARG H . n 
D 2 102 ASP 102 102 102 ASP ASP H . n 
D 2 103 SER 103 103 103 SER SER H . n 
D 2 104 SER 104 104 104 SER SER H . n 
D 2 105 GLY 105 105 105 GLY GLY H . n 
D 2 106 TYR 106 106 106 TYR TYR H . n 
D 2 107 PHE 107 107 107 PHE PHE H . n 
D 2 108 PRO 108 108 108 PRO PRO H . n 
D 2 109 TYR 109 109 109 TYR TYR H . n 
D 2 110 PHE 110 110 110 PHE PHE H . n 
D 2 111 SER 111 111 111 SER SER H . n 
D 2 112 TYR 112 112 112 TYR TYR H . n 
D 2 113 TRP 113 113 113 TRP TRP H . n 
D 2 114 GLY 114 114 114 GLY GLY H . n 
D 2 115 GLN 115 115 115 GLN GLN H . n 
D 2 116 GLY 116 116 116 GLY GLY H . n 
D 2 117 THR 117 117 117 THR THR H . n 
D 2 118 LEU 118 118 118 LEU LEU H . n 
D 2 119 VAL 119 119 119 VAL VAL H . n 
D 2 120 THR 120 120 120 THR THR H . n 
D 2 121 VAL 121 121 ?   ?   ?   H . n 
D 2 122 SER 122 122 ?   ?   ?   H . n 
D 2 123 ALA 123 123 ?   ?   ?   H . n 
D 2 124 ALA 124 124 ?   ?   ?   H . n 
E 3 1   VAL 1   1   ?   ?   ?   L . n 
E 3 2   HIS 2   2   ?   ?   ?   L . n 
E 3 3   SER 3   3   ?   ?   ?   L . n 
E 3 4   ASN 4   4   4   ASN ASN L . n 
E 3 5   ILE 5   5   5   ILE ILE L . n 
E 3 6   VAL 6   6   6   VAL VAL L . n 
E 3 7   LEU 7   7   7   LEU LEU L . n 
E 3 8   THR 8   8   8   THR THR L . n 
E 3 9   GLN 9   9   9   GLN GLN L . n 
E 3 10  SER 10  10  10  SER SER L . n 
E 3 11  PRO 11  11  11  PRO PRO L . n 
E 3 12  ALA 12  12  12  ALA ALA L . n 
E 3 13  SER 13  13  13  SER SER L . n 
E 3 14  LEU 14  14  14  LEU LEU L . n 
E 3 15  ALA 15  15  15  ALA ALA L . n 
E 3 16  VAL 16  16  16  VAL VAL L . n 
E 3 17  SER 17  17  17  SER SER L . n 
E 3 18  LEU 18  18  18  LEU LEU L . n 
E 3 19  GLY 19  19  19  GLY GLY L . n 
E 3 20  GLN 20  20  20  GLN GLN L . n 
E 3 21  ARG 21  21  21  ARG ARG L . n 
E 3 22  ALA 22  22  22  ALA ALA L . n 
E 3 23  THR 23  23  23  THR THR L . n 
E 3 24  ILE 24  24  24  ILE ILE L . n 
E 3 25  SER 25  25  25  SER SER L . n 
E 3 26  CYS 26  26  26  CYS CYS L . n 
E 3 27  ARG 27  27  27  ARG ARG L . n 
E 3 28  ALA 28  28  28  ALA ALA L . n 
E 3 29  SER 29  29  29  SER SER L . n 
E 3 30  GLU 30  30  30  GLU GLU L . n 
E 3 31  SER 31  31  31  SER SER L . n 
E 3 32  VAL 32  32  32  VAL VAL L . n 
E 3 33  ASP 33  33  33  ASP ASP L . n 
E 3 34  HIS 34  34  34  HIS HIS L . n 
E 3 35  SER 35  35  35  SER SER L . n 
E 3 36  GLY 36  36  36  GLY GLY L . n 
E 3 37  ASN 37  37  37  ASN ASN L . n 
E 3 38  ASN 38  38  38  ASN ASN L . n 
E 3 39  PHE 39  39  39  PHE PHE L . n 
E 3 40  ILE 40  40  40  ILE ILE L . n 
E 3 41  HIS 41  41  41  HIS HIS L . n 
E 3 42  TRP 42  42  42  TRP TRP L . n 
E 3 43  TYR 43  43  43  TYR TYR L . n 
E 3 44  GLN 44  44  44  GLN GLN L . n 
E 3 45  GLN 45  45  45  GLN GLN L . n 
E 3 46  LYS 46  46  46  LYS LYS L . n 
E 3 47  PRO 47  47  47  PRO PRO L . n 
E 3 48  GLY 48  48  48  GLY GLY L . n 
E 3 49  GLN 49  49  49  GLN GLN L . n 
E 3 50  PRO 50  50  50  PRO PRO L . n 
E 3 51  PRO 51  51  51  PRO PRO L . n 
E 3 52  LYS 52  52  52  LYS LYS L . n 
E 3 53  LEU 53  53  53  LEU LEU L . n 
E 3 54  LEU 54  54  54  LEU LEU L . n 
E 3 55  ILE 55  55  55  ILE ILE L . n 
E 3 56  TYR 56  56  56  TYR TYR L . n 
E 3 57  LEU 57  57  57  LEU LEU L . n 
E 3 58  ALA 58  58  58  ALA ALA L . n 
E 3 59  SER 59  59  59  SER SER L . n 
E 3 60  HIS 60  60  60  HIS HIS L . n 
E 3 61  LEU 61  61  61  LEU LEU L . n 
E 3 62  GLU 62  62  62  GLU GLU L . n 
E 3 63  SER 63  63  63  SER SER L . n 
E 3 64  GLY 64  64  64  GLY GLY L . n 
E 3 65  VAL 65  65  65  VAL VAL L . n 
E 3 66  PRO 66  66  66  PRO PRO L . n 
E 3 67  ALA 67  67  67  ALA ALA L . n 
E 3 68  ARG 68  68  68  ARG ARG L . n 
E 3 69  PHE 69  69  69  PHE PHE L . n 
E 3 70  SER 70  70  70  SER SER L . n 
E 3 71  GLY 71  71  71  GLY GLY L . n 
E 3 72  SER 72  72  72  SER SER L . n 
E 3 73  GLY 73  73  73  GLY GLY L . n 
E 3 74  SER 74  74  74  SER SER L . n 
E 3 75  ARG 75  75  75  ARG ARG L . n 
E 3 76  THR 76  76  76  THR THR L . n 
E 3 77  ASP 77  77  77  ASP ASP L . n 
E 3 78  PHE 78  78  78  PHE PHE L . n 
E 3 79  THR 79  79  79  THR THR L . n 
E 3 80  LEU 80  80  80  LEU LEU L . n 
E 3 81  THR 81  81  81  THR THR L . n 
E 3 82  ILE 82  82  82  ILE ILE L . n 
E 3 83  ASP 83  83  83  ASP ASP L . n 
E 3 84  PRO 84  84  84  PRO PRO L . n 
E 3 85  VAL 85  85  85  VAL VAL L . n 
E 3 86  GLU 86  86  86  GLU GLU L . n 
E 3 87  ALA 87  87  87  ALA ALA L . n 
E 3 88  ASP 88  88  88  ASP ASP L . n 
E 3 89  ASP 89  89  89  ASP ASP L . n 
E 3 90  PHE 90  90  90  PHE PHE L . n 
E 3 91  ALA 91  91  91  ALA ALA L . n 
E 3 92  THR 92  92  92  THR THR L . n 
E 3 93  TYR 93  93  93  TYR TYR L . n 
E 3 94  TYR 94  94  94  TYR TYR L . n 
E 3 95  CYS 95  95  95  CYS CYS L . n 
E 3 96  GLN 96  96  96  GLN GLN L . n 
E 3 97  GLN 97  97  97  GLN GLN L . n 
E 3 98  ASN 98  98  98  ASN ASN L . n 
E 3 99  ASN 99  99  99  ASN ASN L . n 
E 3 100 GLU 100 100 100 GLU GLU L . n 
E 3 101 VAL 101 101 101 VAL VAL L . n 
E 3 102 PRO 102 102 102 PRO PRO L . n 
E 3 103 LEU 103 103 103 LEU LEU L . n 
E 3 104 THR 104 104 104 THR THR L . n 
E 3 105 PHE 105 105 105 PHE PHE L . n 
E 3 106 GLY 106 106 106 GLY GLY L . n 
E 3 107 ALA 107 107 107 ALA ALA L . n 
E 3 108 GLY 108 108 108 GLY GLY L . n 
E 3 109 THR 109 109 109 THR THR L . n 
E 3 110 LYS 110 110 110 LYS LYS L . n 
E 3 111 LEU 111 111 111 LEU LEU L . n 
E 3 112 GLU 112 112 ?   ?   ?   L . n 
E 3 113 ILE 113 113 ?   ?   ?   L . n 
E 3 114 LYS 114 114 ?   ?   ?   L . n 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8W5N 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8W5N 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8W5N 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     8W5N 
_struct.title                        'Cryo-EM structure of Qb-Ab21' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8W5N 
_struct_keywords.text            'Qb, Antibody, cryo-EM, IMMUNE SYSTEM' 
_struct_keywords.pdbx_keywords   'IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 1 ? 
D N N 2 ? 
E N N 3 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP A1_BPQBE Q8LTE1 ? 1 
;MAKLETVTLGNIGKDGKQTLVLNPRGVNPTNGVASLSQAGAVPALEKRVTVSVSQPSRNRKNYKVQVKIQNPTACTANGS
CDPSVTRQAYADVTFSFTQYSTDEERAFVRTELAALLASPLLIDAIDQLNPAY
;
1 
2 PDB 8W5N     8W5N   ? 2 ? 1 
3 PDB 8W5N     8W5N   ? 3 ? 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8W5N A 1 ? 133 ? Q8LTE1 1 ? 133 ? 0 132 
2 1 8W5N B 1 ? 133 ? Q8LTE1 1 ? 133 ? 0 132 
3 1 8W5N C 1 ? 133 ? Q8LTE1 1 ? 133 ? 0 132 
4 2 8W5N H 1 ? 124 ? 8W5N   1 ? 124 ? 1 124 
5 3 8W5N L 1 ? 114 ? 8W5N   1 ? 114 ? 1 114 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 'complete icosahedral assembly'                ? 300-meric  300 
2 'icosahedral asymmetric unit'                  ? pentameric 5   
3 'icosahedral pentamer'                         ? 25-meric   25  
4 'icosahedral 23 hexamer'                       ? 30-meric   30  
5 'icosahedral asymmetric unit, std point frame' ? pentameric 5   
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 '(1-60)'           A,B,C,D,E 
2 1                  A,B,C,D,E 
3 '(1-5)'            A,B,C,D,E 
4 '(1,2,6,10,23,24)' A,B,C,D,E 
5 P                  A,B,C,D,E 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
P  'transform to point frame' ?     ?     1.00000000  0.00000000  0.00000000  -264.00000 0.00000000  1.00000000  0.00000000  
-264.00000 0.00000000  0.00000000  1.00000000  -264.00000 
1  'identity operation'       1_555 x,y,z 1.00000000  0.00000000  0.00000000  0.00000    0.00000000  1.00000000  0.00000000  
0.00000    0.00000000  0.00000000  1.00000000  0.00000    
2  'point symmetry operation' ?     ?     0.30901699  -0.80901699 0.50000000  264.00000  0.80901699  0.50000000  0.30901699  
-163.16097 -0.50000000 0.30901699  0.80901699  100.83903  
3  'point symmetry operation' ?     ?     -0.80901699 -0.50000000 0.30901699  528.00000  0.50000000  -0.30901699 0.80901699  
0.00000    -0.30901699 0.80901699  0.50000000  0.00000    
4  'point symmetry operation' ?     ?     -0.80901699 0.50000000  -0.30901699 427.16097  -0.50000000 -0.30901699 0.80901699  
264.00000  0.30901699  0.80901699  0.50000000  -163.16097 
5  'point symmetry operation' ?     ?     0.30901699  0.80901699  -0.50000000 100.83903  -0.80901699 0.50000000  0.30901699  
264.00000  0.50000000  0.30901699  0.80901699  -163.16097 
6  'point symmetry operation' ?     ?     -1.00000000 0.00000000  0.00000000  528.00000  0.00000000  -1.00000000 0.00000000  
528.00000  0.00000000  0.00000000  1.00000000  0.00000    
7  'point symmetry operation' ?     ?     -0.30901699 0.80901699  -0.50000000 264.00000  -0.80901699 -0.50000000 -0.30901699 
691.16097  -0.50000000 0.30901699  0.80901699  100.83903  
8  'point symmetry operation' ?     ?     0.80901699  0.50000000  -0.30901699 0.00000    -0.50000000 0.30901699  -0.80901699 
528.00000  -0.30901699 0.80901699  0.50000000  0.00000    
9  'point symmetry operation' ?     ?     0.80901699  -0.50000000 0.30901699  100.83903  0.50000000  0.30901699  -0.80901699 
264.00000  0.30901699  0.80901699  0.50000000  -163.16097 
10 'point symmetry operation' ?     ?     -0.30901699 -0.80901699 0.50000000  427.16097  0.80901699  -0.50000000 -0.30901699 
264.00000  0.50000000  0.30901699  0.80901699  -163.16097 
11 'point symmetry operation' ?     ?     -1.00000000 0.00000000  0.00000000  528.00000  0.00000000  1.00000000  0.00000000  
0.00000    0.00000000  0.00000000  -1.00000000 528.00000  
12 'point symmetry operation' ?     ?     -0.30901699 0.80901699  -0.50000000 264.00000  0.80901699  0.50000000  0.30901699  
-163.16097 0.50000000  -0.30901699 -0.80901699 427.16097  
13 'point symmetry operation' ?     ?     0.80901699  0.50000000  -0.30901699 0.00000    0.50000000  -0.30901699 0.80901699  
0.00000    0.30901699  -0.80901699 -0.50000000 528.00000  
14 'point symmetry operation' ?     ?     0.80901699  -0.50000000 0.30901699  100.83903  -0.50000000 -0.30901699 0.80901699  
264.00000  -0.30901699 -0.80901699 -0.50000000 691.16097  
15 'point symmetry operation' ?     ?     -0.30901699 -0.80901699 0.50000000  427.16097  -0.80901699 0.50000000  0.30901699  
264.00000  -0.50000000 -0.30901699 -0.80901699 691.16097  
16 'point symmetry operation' ?     ?     1.00000000  0.00000000  0.00000000  0.00000    0.00000000  -1.00000000 0.00000000  
528.00000  0.00000000  0.00000000  -1.00000000 528.00000  
17 'point symmetry operation' ?     ?     0.30901699  -0.80901699 0.50000000  264.00000  -0.80901699 -0.50000000 -0.30901699 
691.16097  0.50000000  -0.30901699 -0.80901699 427.16097  
18 'point symmetry operation' ?     ?     -0.80901699 -0.50000000 0.30901699  528.00000  -0.50000000 0.30901699  -0.80901699 
528.00000  0.30901699  -0.80901699 -0.50000000 528.00000  
19 'point symmetry operation' ?     ?     -0.80901699 0.50000000  -0.30901699 427.16097  0.50000000  0.30901699  -0.80901699 
264.00000  -0.30901699 -0.80901699 -0.50000000 691.16097  
20 'point symmetry operation' ?     ?     0.30901699  0.80901699  -0.50000000 100.83903  0.80901699  -0.50000000 -0.30901699 
264.00000  -0.50000000 -0.30901699 -0.80901699 691.16097  
21 'point symmetry operation' ?     ?     0.00000000  0.00000000  1.00000000  0.00000    1.00000000  0.00000000  0.00000000  
0.00000    0.00000000  1.00000000  0.00000000  0.00000    
22 'point symmetry operation' ?     ?     -0.50000000 0.30901699  0.80901699  100.83903  0.30901699  -0.80901699 0.50000000  
264.00000  0.80901699  0.50000000  0.30901699  -163.16097 
23 'point symmetry operation' ?     ?     -0.30901699 0.80901699  0.50000000  0.00000    -0.80901699 -0.50000000 0.30901699  
528.00000  0.50000000  -0.30901699 0.80901699  0.00000    
24 'point symmetry operation' ?     ?     0.30901699  0.80901699  0.50000000  -163.16097 -0.80901699 0.50000000  -0.30901699 
427.16097  -0.50000000 -0.30901699 0.80901699  264.00000  
25 'point symmetry operation' ?     ?     0.50000000  0.30901699  0.80901699  -163.16097 0.30901699  0.80901699  -0.50000000 
100.83903  -0.80901699 0.50000000  0.30901699  264.00000  
26 'point symmetry operation' ?     ?     0.00000000  0.00000000  1.00000000  0.00000    -1.00000000 0.00000000  0.00000000  
528.00000  0.00000000  -1.00000000 0.00000000  528.00000  
27 'point symmetry operation' ?     ?     -0.50000000 0.30901699  0.80901699  100.83903  -0.30901699 0.80901699  -0.50000000 
264.00000  -0.80901699 -0.50000000 -0.30901699 691.16097  
28 'point symmetry operation' ?     ?     -0.30901699 0.80901699  0.50000000  0.00000    0.80901699  0.50000000  -0.30901699 
0.00000    -0.50000000 0.30901699  -0.80901699 528.00000  
29 'point symmetry operation' ?     ?     0.30901699  0.80901699  0.50000000  -163.16097 0.80901699  -0.50000000 0.30901699  
100.83903  0.50000000  0.30901699  -0.80901699 264.00000  
30 'point symmetry operation' ?     ?     0.50000000  0.30901699  0.80901699  -163.16097 -0.30901699 -0.80901699 0.50000000  
427.16097  0.80901699  -0.50000000 -0.30901699 264.00000  
31 'point symmetry operation' ?     ?     0.00000000  0.00000000  -1.00000000 528.00000  -1.00000000 0.00000000  0.00000000  
528.00000  0.00000000  1.00000000  0.00000000  0.00000    
32 'point symmetry operation' ?     ?     0.50000000  -0.30901699 -0.80901699 427.16097  -0.30901699 0.80901699  -0.50000000 
264.00000  0.80901699  0.50000000  0.30901699  -163.16097 
33 'point symmetry operation' ?     ?     0.30901699  -0.80901699 -0.50000000 528.00000  0.80901699  0.50000000  -0.30901699 
0.00000    0.50000000  -0.30901699 0.80901699  0.00000    
34 'point symmetry operation' ?     ?     -0.30901699 -0.80901699 -0.50000000 691.16097  0.80901699  -0.50000000 0.30901699  
100.83903  -0.50000000 -0.30901699 0.80901699  264.00000  
35 'point symmetry operation' ?     ?     -0.50000000 -0.30901699 -0.80901699 691.16097  -0.30901699 -0.80901699 0.50000000  
427.16097  -0.80901699 0.50000000  0.30901699  264.00000  
36 'point symmetry operation' ?     ?     0.00000000  0.00000000  -1.00000000 528.00000  1.00000000  0.00000000  0.00000000  
0.00000    0.00000000  -1.00000000 0.00000000  528.00000  
37 'point symmetry operation' ?     ?     0.50000000  -0.30901699 -0.80901699 427.16097  0.30901699  -0.80901699 0.50000000  
264.00000  -0.80901699 -0.50000000 -0.30901699 691.16097  
38 'point symmetry operation' ?     ?     0.30901699  -0.80901699 -0.50000000 528.00000  -0.80901699 -0.50000000 0.30901699  
528.00000  -0.50000000 0.30901699  -0.80901699 528.00000  
39 'point symmetry operation' ?     ?     -0.30901699 -0.80901699 -0.50000000 691.16097  -0.80901699 0.50000000  -0.30901699 
427.16097  0.50000000  0.30901699  -0.80901699 264.00000  
40 'point symmetry operation' ?     ?     -0.50000000 -0.30901699 -0.80901699 691.16097  0.30901699  0.80901699  -0.50000000 
100.83903  0.80901699  -0.50000000 -0.30901699 264.00000  
41 'point symmetry operation' ?     ?     0.00000000  1.00000000  0.00000000  0.00000    0.00000000  0.00000000  1.00000000  
0.00000    1.00000000  0.00000000  0.00000000  0.00000    
42 'point symmetry operation' ?     ?     0.80901699  0.50000000  0.30901699  -163.16097 -0.50000000 0.30901699  0.80901699  
100.83903  0.30901699  -0.80901699 0.50000000  264.00000  
43 'point symmetry operation' ?     ?     0.50000000  -0.30901699 0.80901699  0.00000    -0.30901699 0.80901699  0.50000000  
0.00000    -0.80901699 -0.50000000 0.30901699  528.00000  
44 'point symmetry operation' ?     ?     -0.50000000 -0.30901699 0.80901699  264.00000  0.30901699  0.80901699  0.50000000  
-163.16097 -0.80901699 0.50000000  -0.30901699 427.16097  
45 'point symmetry operation' ?     ?     -0.80901699 0.50000000  0.30901699  264.00000  0.50000000  0.30901699  0.80901699  
-163.16097 0.30901699  0.80901699  -0.50000000 100.83903  
46 'point symmetry operation' ?     ?     0.00000000  -1.00000000 0.00000000  528.00000  0.00000000  0.00000000  1.00000000  
0.00000    -1.00000000 0.00000000  0.00000000  528.00000  
47 'point symmetry operation' ?     ?     -0.80901699 -0.50000000 -0.30901699 691.16097  -0.50000000 0.30901699  0.80901699  
100.83903  -0.30901699 0.80901699  -0.50000000 264.00000  
48 'point symmetry operation' ?     ?     -0.50000000 0.30901699  -0.80901699 528.00000  -0.30901699 0.80901699  0.50000000  
0.00000    0.80901699  0.50000000  -0.30901699 0.00000    
49 'point symmetry operation' ?     ?     0.50000000  0.30901699  -0.80901699 264.00000  0.30901699  0.80901699  0.50000000  
-163.16097 0.80901699  -0.50000000 0.30901699  100.83903  
50 'point symmetry operation' ?     ?     0.80901699  -0.50000000 -0.30901699 264.00000  0.50000000  0.30901699  0.80901699  
-163.16097 -0.30901699 -0.80901699 0.50000000  427.16097  
51 'point symmetry operation' ?     ?     0.00000000  1.00000000  0.00000000  0.00000    0.00000000  0.00000000  -1.00000000 
528.00000  -1.00000000 0.00000000  0.00000000  528.00000  
52 'point symmetry operation' ?     ?     0.80901699  0.50000000  0.30901699  -163.16097 0.50000000  -0.30901699 -0.80901699 
427.16097  -0.30901699 0.80901699  -0.50000000 264.00000  
53 'point symmetry operation' ?     ?     0.50000000  -0.30901699 0.80901699  0.00000    0.30901699  -0.80901699 -0.50000000 
528.00000  0.80901699  0.50000000  -0.30901699 0.00000    
54 'point symmetry operation' ?     ?     -0.50000000 -0.30901699 0.80901699  264.00000  -0.30901699 -0.80901699 -0.50000000 
691.16097  0.80901699  -0.50000000 0.30901699  100.83903  
55 'point symmetry operation' ?     ?     -0.80901699 0.50000000  0.30901699  264.00000  -0.50000000 -0.30901699 -0.80901699 
691.16097  -0.30901699 -0.80901699 0.50000000  427.16097  
56 'point symmetry operation' ?     ?     0.00000000  -1.00000000 0.00000000  528.00000  0.00000000  0.00000000  -1.00000000 
528.00000  1.00000000  0.00000000  0.00000000  0.00000    
57 'point symmetry operation' ?     ?     -0.80901699 -0.50000000 -0.30901699 691.16097  0.50000000  -0.30901699 -0.80901699 
427.16097  0.30901699  -0.80901699 0.50000000  264.00000  
58 'point symmetry operation' ?     ?     -0.50000000 0.30901699  -0.80901699 528.00000  0.30901699  -0.80901699 -0.50000000 
528.00000  -0.80901699 -0.50000000 0.30901699  528.00000  
59 'point symmetry operation' ?     ?     0.50000000  0.30901699  -0.80901699 264.00000  -0.30901699 -0.80901699 -0.50000000 
691.16097  -0.80901699 0.50000000  -0.30901699 427.16097  
60 'point symmetry operation' ?     ?     0.80901699  -0.50000000 -0.30901699 264.00000  -0.50000000 -0.30901699 -0.80901699 
691.16097  0.30901699  0.80901699  -0.50000000 100.83903  
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 AA1 THR A 102 ? LEU A 117 ? THR A 101 LEU A 116 1 ? 16 
HELX_P HELX_P2 AA2 SER A 119 ? ASP A 127 ? SER A 118 ASP A 126 1 ? 9  
HELX_P HELX_P3 AA3 VAL B 42  ? GLU B 46  ? VAL B 41  GLU B 45  5 ? 5  
HELX_P HELX_P4 AA4 THR B 102 ? LEU B 117 ? THR B 101 LEU B 116 1 ? 16 
HELX_P HELX_P5 AA5 LEU B 121 ? ILE B 126 ? LEU B 120 ILE B 125 1 ? 6  
HELX_P HELX_P6 AA6 THR C 102 ? LEU C 117 ? THR C 101 LEU C 116 1 ? 16 
HELX_P HELX_P7 AA7 GLU E 86  ? PHE E 90  ? GLU L 86  PHE L 90  5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 75 SG ? ? ? 1_555 C CYS 81 SG ? ? A CYS 74 C CYS 80 1_555 ? ? ? ? ? ? ? 2.032 ? ? 
disulf2 disulf ? ? D CYS 25 SG ? ? ? 1_555 D CYS 99 SG ? ? H CYS 25 H CYS 99 1_555 ? ? ? ? ? ? ? 2.037 ? ? 
disulf3 disulf ? ? E CYS 26 SG ? ? ? 1_555 E CYS 95 SG ? ? L CYS 26 L CYS 95 1_555 ? ? ? ? ? ? ? 2.032 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 75 ? CYS C 81 ? CYS A 74 ? 1_555 CYS C 80 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS D 25 ? CYS D 99 ? CYS H 25 ? 1_555 CYS H 99 ? 1_555 SG SG . . . None 'Disulfide bridge' 
3 CYS E 26 ? CYS E 95 ? CYS L 26 ? 1_555 CYS L 95 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 12 ? 
AA2 ? 2  ? 
AA3 ? 6  ? 
AA4 ? 2  ? 
AA5 ? 2  ? 
AA6 ? 4  ? 
AA7 ? 4  ? 
AA8 ? 4  ? 
AA9 ? 4  ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1  2  ? anti-parallel 
AA1 2  3  ? anti-parallel 
AA1 3  4  ? anti-parallel 
AA1 4  5  ? anti-parallel 
AA1 5  6  ? anti-parallel 
AA1 6  7  ? anti-parallel 
AA1 7  8  ? anti-parallel 
AA1 8  9  ? anti-parallel 
AA1 9  10 ? anti-parallel 
AA1 10 11 ? anti-parallel 
AA1 11 12 ? anti-parallel 
AA2 1  2  ? anti-parallel 
AA3 1  2  ? anti-parallel 
AA3 2  3  ? anti-parallel 
AA3 3  4  ? anti-parallel 
AA3 4  5  ? anti-parallel 
AA3 5  6  ? anti-parallel 
AA4 1  2  ? anti-parallel 
AA5 1  2  ? anti-parallel 
AA6 1  2  ? anti-parallel 
AA6 2  3  ? anti-parallel 
AA6 3  4  ? anti-parallel 
AA7 1  2  ? anti-parallel 
AA7 2  3  ? anti-parallel 
AA7 3  4  ? anti-parallel 
AA8 1  2  ? anti-parallel 
AA8 2  3  ? anti-parallel 
AA8 3  4  ? anti-parallel 
AA9 1  2  ? anti-parallel 
AA9 2  3  ? anti-parallel 
AA9 3  4  ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1  VAL A 7  ? ILE A 12  ? VAL A 6  ILE A 11  
AA1 2  GLN A 18 ? PRO A 24  ? GLN A 17 PRO A 23  
AA1 3  ALA A 34 ? GLN A 38  ? ALA A 33 GLN A 37  
AA1 4  ARG A 48 ? SER A 54  ? ARG A 47 SER A 53  
AA1 5  TYR A 63 ? GLN A 70  ? TYR A 62 GLN A 69  
AA1 6  TYR A 90 ? PHE A 97  ? TYR A 89 PHE A 96  
AA1 7  SER B 84 ? SER B 96  ? SER B 83 SER B 95  
AA1 8  LYS B 64 ? CYS B 75  ? LYS B 63 CYS B 74  
AA1 9  ARG B 48 ? SER B 54  ? ARG B 47 SER B 53  
AA1 10 VAL B 33 ? SER B 37  ? VAL B 32 SER B 36  
AA1 11 GLN B 18 ? ASN B 28  ? GLN B 17 ASN B 27  
AA1 12 VAL B 7  ? ILE B 12  ? VAL B 6  ILE B 11  
AA2 1  ALA A 74 ? CYS A 75  ? ALA A 73 CYS A 74  
AA2 2  SER A 84 ? VAL A 85  ? SER A 83 VAL A 84  
AA3 1  VAL C 7  ? ILE C 12  ? VAL C 6  ILE C 11  
AA3 2  GLN C 18 ? VAL C 27  ? GLN C 17 VAL C 26  
AA3 3  ALA C 34 ? GLN C 38  ? ALA C 33 GLN C 37  
AA3 4  ARG C 48 ? VAL C 53  ? ARG C 47 VAL C 52  
AA3 5  VAL C 65 ? GLN C 70  ? VAL C 64 GLN C 69  
AA3 6  TYR C 90 ? THR C 94  ? TYR C 89 THR C 93  
AA4 1  ASN C 62 ? TYR C 63  ? ASN C 61 TYR C 62  
AA4 2  PHE C 97 ? THR C 98  ? PHE C 96 THR C 97  
AA5 1  ALA C 74 ? CYS C 75  ? ALA C 73 CYS C 74  
AA5 2  SER C 84 ? VAL C 85  ? SER C 83 VAL C 84  
AA6 1  GLU D 9  ? SER D 10  ? GLU H 9  SER H 10  
AA6 2  SER D 20 ? CYS D 25  ? SER H 20 CYS H 25  
AA6 3  ASN D 81 ? SER D 87  ? ASN H 81 SER H 87  
AA6 4  THR D 72 ? ASP D 76  ? THR H 72 ASP H 76  
AA7 1  ILE D 61 ? TYR D 63  ? ILE H 61 TYR H 63  
AA7 2  LEU D 48 ? ILE D 54  ? LEU H 48 ILE H 54  
AA7 3  MET D 37 ? GLN D 42  ? MET H 37 GLN H 42  
AA7 4  HIS D 98 ? ARG D 101 ? HIS H 98 ARG H 101 
AA8 1  THR E 8  ? GLN E 9   ? THR L 8  GLN L 9   
AA8 2  ALA E 22 ? ARG E 27  ? ALA L 22 ARG L 27  
AA8 3  ASP E 77 ? ILE E 82  ? ASP L 77 ILE L 82  
AA8 4  PHE E 69 ? GLY E 73  ? PHE L 69 GLY L 73  
AA9 1  HIS E 60 ? LEU E 61  ? HIS L 60 LEU L 61  
AA9 2  LYS E 52 ? TYR E 56  ? LYS L 52 TYR L 56  
AA9 3  ILE E 40 ? GLN E 44  ? ILE L 40 GLN L 44  
AA9 4  CYS E 95 ? GLN E 97  ? CYS L 95 GLN L 97  
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1  2  N VAL A 7  ? N VAL A 6  O LEU A 22 ? O LEU A 21 
AA1 2  3  N ASN A 23 ? N ASN A 22 O SER A 37 ? O SER A 36 
AA1 3  4  N ALA A 34 ? N ALA A 33 O VAL A 51 ? O VAL A 50 
AA1 4  5  N SER A 54 ? N SER A 53 O LYS A 64 ? O LYS A 63 
AA1 5  6  N VAL A 65 ? N VAL A 64 O PHE A 95 ? O PHE A 94 
AA1 6  7  N TYR A 90 ? N TYR A 89 O SER B 96 ? O SER B 95 
AA1 7  8  O PHE B 95 ? O PHE B 94 N VAL B 65 ? N VAL B 64 
AA1 8  9  O LYS B 68 ? O LYS B 67 N THR B 50 ? N THR B 49 
AA1 9  10 O VAL B 49 ? O VAL B 48 N LEU B 36 ? N LEU B 35 
AA1 10 11 O SER B 37 ? O SER B 36 N ASN B 23 ? N ASN B 22 
AA1 11 12 O LEU B 20 ? O LEU B 19 N LEU B 9  ? N LEU B 8  
AA2 1  2  N CYS A 75 ? N CYS A 74 O SER A 84 ? O SER A 83 
AA3 1  2  N VAL C 7  ? N VAL C 6  O LEU C 22 ? O LEU C 21 
AA3 2  3  N ASN C 23 ? N ASN C 22 O SER C 37 ? O SER C 36 
AA3 3  4  N ALA C 34 ? N ALA C 33 O VAL C 51 ? O VAL C 50 
AA3 4  5  N SER C 52 ? N SER C 51 O GLN C 66 ? O GLN C 65 
AA3 5  6  N VAL C 67 ? N VAL C 66 O VAL C 93 ? O VAL C 92 
AA4 1  2  N TYR C 63 ? N TYR C 62 O PHE C 97 ? O PHE C 96 
AA5 1  2  O CYS C 75 ? O CYS C 74 N SER C 84 ? N SER C 83 
AA6 1  2  N SER D 10 ? N SER H 10 O SER D 24 ? O SER H 24 
AA6 2  3  N LEU D 21 ? N LEU H 21 O MET D 86 ? O MET H 86 
AA6 3  4  O ASN D 81 ? O ASN H 81 N ASP D 76 ? N ASP H 76 
AA7 1  2  O TYR D 62 ? O TYR H 62 N THR D 53 ? N THR H 53 
AA7 2  3  O GLU D 49 ? O GLU H 49 N ARG D 41 ? N ARG H 41 
AA7 3  4  N VAL D 40 ? N VAL H 40 O HIS D 98 ? O HIS H 98 
AA8 1  2  N THR E 8  ? N THR L 8  O ARG E 27 ? O ARG L 27 
AA8 2  3  N CYS E 26 ? N CYS L 26 O PHE E 78 ? O PHE L 78 
AA8 3  4  O THR E 79 ? O THR L 79 N SER E 72 ? N SER L 72 
AA9 1  2  O HIS E 60 ? O HIS L 60 N TYR E 56 ? N TYR L 56 
AA9 2  3  O LEU E 54 ? O LEU L 54 N TRP E 42 ? N TRP L 42 
AA9 3  4  N HIS E 41 ? N HIS L 41 O GLN E 96 ? O GLN L 96 
# 
_pdbx_entry_details.entry_id                   8W5N 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 LEU A 44  ? ? -145.10 33.69   
2  1 LYS B 60  ? ? 72.58   -5.16   
3  1 VAL C 41  ? ? 54.38   82.45   
4  1 PRO C 42  ? ? -63.50  1.22    
5  1 SER C 95  ? ? -162.80 118.62  
6  1 ALA H 27  ? ? 60.70   67.90   
7  1 VAL H 51  ? ? -109.24 -63.32  
8  1 SER H 55  ? ? -79.56  -162.76 
9  1 HIS H 88  ? ? 73.10   -10.98  
10 1 LEU H 89  ? ? 35.57   58.70   
11 1 PHE H 110 ? ? 62.48   68.76   
12 1 PHE L 39  ? ? -100.40 73.53   
13 1 LEU L 54  ? ? -101.53 -60.70  
14 1 ALA L 58  ? ? 67.08   -5.71   
15 1 ARG L 75  ? ? 71.37   -17.00  
16 1 THR L 76  ? ? -133.79 -40.27  
17 1 PRO L 84  ? ? -34.90  128.98  
# 
_pdbx_validate_peptide_omega.id               1 
_pdbx_validate_peptide_omega.PDB_model_num    1 
_pdbx_validate_peptide_omega.auth_comp_id_1   ASP 
_pdbx_validate_peptide_omega.auth_asym_id_1   L 
_pdbx_validate_peptide_omega.auth_seq_id_1    83 
_pdbx_validate_peptide_omega.PDB_ins_code_1   ? 
_pdbx_validate_peptide_omega.label_alt_id_1   ? 
_pdbx_validate_peptide_omega.auth_comp_id_2   PRO 
_pdbx_validate_peptide_omega.auth_asym_id_2   L 
_pdbx_validate_peptide_omega.auth_seq_id_2    84 
_pdbx_validate_peptide_omega.PDB_ins_code_2   ? 
_pdbx_validate_peptide_omega.label_alt_id_2   ? 
_pdbx_validate_peptide_omega.omega            -129.07 
# 
_pdbx_point_symmetry.entry_id             8W5N 
_pdbx_point_symmetry.Schoenflies_symbol   I 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8W5N 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8W5N 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.1 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               12102 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Complex of Qb-Ab21' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3' 
# 
_em_imaging.entry_id                        8W5N 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TECNAI ARCTICA' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            200 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1200 
_em_imaging.nominal_defocus_max             1600 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8W5N 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8W5N 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 0   ? A MET 1   
2  1 Y 1 B MET 0   ? B MET 1   
3  1 Y 1 C MET 0   ? C MET 1   
4  1 Y 1 H VAL 1   ? D VAL 1   
5  1 Y 1 H HIS 2   ? D HIS 2   
6  1 Y 1 H SER 3   ? D SER 3   
7  1 Y 1 H VAL 121 ? D VAL 121 
8  1 Y 1 H SER 122 ? D SER 122 
9  1 Y 1 H ALA 123 ? D ALA 123 
10 1 Y 1 H ALA 124 ? D ALA 124 
11 1 Y 1 L VAL 1   ? E VAL 1   
12 1 Y 1 L HIS 2   ? E HIS 2   
13 1 Y 1 L SER 3   ? E SER 3   
14 1 Y 1 L GLU 112 ? E GLU 112 
15 1 Y 1 L ILE 113 ? E ILE 113 
16 1 Y 1 L LYS 114 ? E LYS 114 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-08-27 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8W5N 
_em_admin.last_update        2025-02-26 
_em_admin.map_release_date   2025-02-26 
_em_admin.title              'Cryo-EM structure of Qb-Ab21' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          10088 
_em_entity_assembly_naturalsource.organism             Mus 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K2 SUMMIT (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ?      ?          
'MODEL REFINEMENT'         ? 2  ? ? ? PHENIX 1.13_2998: 
'IMAGE ACQUISITION'        ? 3  ? ? 1 ?      ?          
MASKING                    ? 4  ? ? ? ?      ?          
'CTF CORRECTION'           ? 5  1 ? ? ?      ?          
'LAYERLINE INDEXING'       ? 6  ? ? ? ?      ?          
'DIFFRACTION INDEXING'     ? 7  ? ? ? ?      ?          
'MODEL FITTING'            ? 8  ? ? ? ?      ?          
OTHER                      ? 9  ? ? ? ?      ?          
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ?      ?          
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ?      ?          
CLASSIFICATION             ? 12 1 ? ? ?      ?          
RECONSTRUCTION             ? 13 1 ? ? ?      ?          
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Natural Science Foundation of China (NSFC)' China 81991495    1 
'National Natural Science Foundation of China (NSFC)' China 32241029    2 
'Chinese Academy of Sciences'                         China XDB29050600 3 
'Chinese Academy of Sciences'                         China XDB37010100 4 
# 
_atom_sites.entry_id                    8W5N 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . ALA A 1 2   ? 299.253 315.455 381.600 1.00 46.36  ? 1   ALA A N   1 
ATOM 2    C CA  . ALA A 1 2   ? 300.364 315.832 382.459 1.00 46.36  ? 1   ALA A CA  1 
ATOM 3    C C   . ALA A 1 2   ? 301.679 315.374 381.843 1.00 46.36  ? 1   ALA A C   1 
ATOM 4    O O   . ALA A 1 2   ? 301.927 315.601 380.665 1.00 46.36  ? 1   ALA A O   1 
ATOM 5    C CB  . ALA A 1 2   ? 300.183 315.250 383.847 1.00 46.36  ? 1   ALA A CB  1 
ATOM 6    N N   . LYS A 1 3   ? 302.519 314.725 382.642 1.00 50.58  ? 2   LYS A N   1 
ATOM 7    C CA  . LYS A 1 3   ? 303.810 314.227 382.194 1.00 50.58  ? 2   LYS A CA  1 
ATOM 8    C C   . LYS A 1 3   ? 303.841 312.714 382.338 1.00 50.58  ? 2   LYS A C   1 
ATOM 9    O O   . LYS A 1 3   ? 303.421 312.174 383.364 1.00 50.58  ? 2   LYS A O   1 
ATOM 10   C CB  . LYS A 1 3   ? 304.946 314.856 383.006 1.00 50.58  ? 2   LYS A CB  1 
ATOM 11   C CG  . LYS A 1 3   ? 306.344 314.415 382.608 1.00 50.58  ? 2   LYS A CG  1 
ATOM 12   C CD  . LYS A 1 3   ? 306.713 314.950 381.237 1.00 50.58  ? 2   LYS A CD  1 
ATOM 13   C CE  . LYS A 1 3   ? 308.173 314.689 380.908 1.00 50.58  ? 2   LYS A CE  1 
ATOM 14   N NZ  . LYS A 1 3   ? 308.468 313.242 380.742 1.00 50.58  ? 2   LYS A NZ  1 
ATOM 15   N N   . LEU A 1 4   ? 304.337 312.028 381.309 1.00 47.93  ? 3   LEU A N   1 
ATOM 16   C CA  . LEU A 1 4   ? 304.510 310.586 381.409 1.00 47.93  ? 3   LEU A CA  1 
ATOM 17   C C   . LEU A 1 4   ? 305.669 310.240 382.327 1.00 47.93  ? 3   LEU A C   1 
ATOM 18   O O   . LEU A 1 4   ? 306.823 310.177 381.896 1.00 47.93  ? 3   LEU A O   1 
ATOM 19   C CB  . LEU A 1 4   ? 304.728 309.949 380.040 1.00 47.93  ? 3   LEU A CB  1 
ATOM 20   C CG  . LEU A 1 4   ? 303.471 309.764 379.203 1.00 47.93  ? 3   LEU A CG  1 
ATOM 21   C CD1 . LEU A 1 4   ? 303.803 309.166 377.861 1.00 47.93  ? 3   LEU A CD1 1 
ATOM 22   C CD2 . LEU A 1 4   ? 302.520 308.863 379.950 1.00 47.93  ? 3   LEU A CD2 1 
ATOM 23   N N   . GLU A 1 5   ? 305.362 310.015 383.591 1.00 50.87  ? 4   GLU A N   1 
ATOM 24   C CA  . GLU A 1 5   ? 306.324 309.570 384.576 1.00 50.87  ? 4   GLU A CA  1 
ATOM 25   C C   . GLU A 1 5   ? 306.092 308.095 384.857 1.00 50.87  ? 4   GLU A C   1 
ATOM 26   O O   . GLU A 1 5   ? 305.262 307.440 384.223 1.00 50.87  ? 4   GLU A O   1 
ATOM 27   C CB  . GLU A 1 5   ? 306.196 310.390 385.856 1.00 50.87  ? 4   GLU A CB  1 
ATOM 28   C CG  . GLU A 1 5   ? 306.484 311.856 385.672 1.00 50.87  ? 4   GLU A CG  1 
ATOM 29   C CD  . GLU A 1 5   ? 306.315 312.637 386.955 1.00 50.87  ? 4   GLU A CD  1 
ATOM 30   O OE1 . GLU A 1 5   ? 305.877 312.040 387.958 1.00 50.87  ? 4   GLU A OE1 1 
ATOM 31   O OE2 . GLU A 1 5   ? 306.612 313.850 386.957 1.00 50.87  ? 4   GLU A OE2 1 
ATOM 32   N N   . THR A 1 6   ? 306.831 307.572 385.825 1.00 49.22  ? 5   THR A N   1 
ATOM 33   C CA  . THR A 1 6   ? 306.559 306.233 386.309 1.00 49.22  ? 5   THR A CA  1 
ATOM 34   C C   . THR A 1 6   ? 305.407 306.262 387.305 1.00 49.22  ? 5   THR A C   1 
ATOM 35   O O   . THR A 1 6   ? 305.165 307.263 387.986 1.00 49.22  ? 5   THR A O   1 
ATOM 36   C CB  . THR A 1 6   ? 307.812 305.617 386.931 1.00 49.22  ? 5   THR A CB  1 
ATOM 37   O OG1 . THR A 1 6   ? 307.537 304.271 387.333 1.00 49.22  ? 5   THR A OG1 1 
ATOM 38   C CG2 . THR A 1 6   ? 308.298 306.422 388.124 1.00 49.22  ? 5   THR A CG2 1 
ATOM 39   N N   . VAL A 1 7   ? 304.657 305.166 387.347 1.00 45.27  ? 6   VAL A N   1 
ATOM 40   C CA  . VAL A 1 7   ? 303.433 305.085 388.132 1.00 45.27  ? 6   VAL A CA  1 
ATOM 41   C C   . VAL A 1 7   ? 303.535 303.878 389.050 1.00 45.27  ? 6   VAL A C   1 
ATOM 42   O O   . VAL A 1 7   ? 303.633 302.742 388.576 1.00 45.27  ? 6   VAL A O   1 
ATOM 43   C CB  . VAL A 1 7   ? 302.184 304.979 387.243 1.00 45.27  ? 6   VAL A CB  1 
ATOM 44   C CG1 . VAL A 1 7   ? 300.959 304.808 388.094 1.00 45.27  ? 6   VAL A CG1 1 
ATOM 45   C CG2 . VAL A 1 7   ? 302.036 306.212 386.384 1.00 45.27  ? 6   VAL A CG2 1 
ATOM 46   N N   . THR A 1 8   ? 303.512 304.121 390.353 1.00 45.97  ? 7   THR A N   1 
ATOM 47   C CA  . THR A 1 8   ? 303.516 303.061 391.349 1.00 45.97  ? 7   THR A CA  1 
ATOM 48   C C   . THR A 1 8   ? 302.102 302.924 391.893 1.00 45.97  ? 7   THR A C   1 
ATOM 49   O O   . THR A 1 8   ? 301.635 303.783 392.645 1.00 45.97  ? 7   THR A O   1 
ATOM 50   C CB  . THR A 1 8   ? 304.498 303.365 392.475 1.00 45.97  ? 7   THR A CB  1 
ATOM 51   O OG1 . THR A 1 8   ? 304.071 304.542 393.168 1.00 45.97  ? 7   THR A OG1 1 
ATOM 52   C CG2 . THR A 1 8   ? 305.885 303.599 391.915 1.00 45.97  ? 7   THR A CG2 1 
ATOM 53   N N   . LEU A 1 9   ? 301.423 301.851 391.509 1.00 43.88  ? 8   LEU A N   1 
ATOM 54   C CA  . LEU A 1 9   ? 300.079 301.571 391.991 1.00 43.88  ? 8   LEU A CA  1 
ATOM 55   C C   . LEU A 1 9   ? 300.181 300.742 393.263 1.00 43.88  ? 8   LEU A C   1 
ATOM 56   O O   . LEU A 1 9   ? 300.706 299.625 393.239 1.00 43.88  ? 8   LEU A O   1 
ATOM 57   C CB  . LEU A 1 9   ? 299.274 300.837 390.925 1.00 43.88  ? 8   LEU A CB  1 
ATOM 58   C CG  . LEU A 1 9   ? 299.043 301.606 389.628 1.00 43.88  ? 8   LEU A CG  1 
ATOM 59   C CD1 . LEU A 1 9   ? 298.325 300.748 388.623 1.00 43.88  ? 8   LEU A CD1 1 
ATOM 60   C CD2 . LEU A 1 9   ? 298.263 302.861 389.898 1.00 43.88  ? 8   LEU A CD2 1 
ATOM 61   N N   . GLY A 1 10  ? 299.697 301.288 394.371 1.00 47.52  ? 9   GLY A N   1 
ATOM 62   C CA  . GLY A 1 10  ? 299.788 300.596 395.639 1.00 47.52  ? 9   GLY A CA  1 
ATOM 63   C C   . GLY A 1 10  ? 298.446 300.107 396.131 1.00 47.52  ? 9   GLY A C   1 
ATOM 64   O O   . GLY A 1 10  ? 297.411 300.618 395.693 1.00 47.52  ? 9   GLY A O   1 
ATOM 65   N N   . ASN A 1 11  ? 298.471 299.137 397.056 1.00 51.33  ? 10  ASN A N   1 
ATOM 66   C CA  . ASN A 1 11  ? 297.281 298.478 397.609 1.00 51.33  ? 10  ASN A CA  1 
ATOM 67   C C   . ASN A 1 11  ? 296.412 297.890 396.502 1.00 51.33  ? 10  ASN A C   1 
ATOM 68   O O   . ASN A 1 11  ? 295.195 298.074 396.471 1.00 51.33  ? 10  ASN A O   1 
ATOM 69   C CB  . ASN A 1 11  ? 296.475 299.426 398.500 1.00 51.33  ? 10  ASN A CB  1 
ATOM 70   C CG  . ASN A 1 11  ? 297.246 299.864 399.722 1.00 51.33  ? 10  ASN A CG  1 
ATOM 71   O OD1 . ASN A 1 11  ? 297.957 299.075 400.340 1.00 51.33  ? 10  ASN A OD1 1 
ATOM 72   N ND2 . ASN A 1 11  ? 297.117 301.134 400.074 1.00 51.33  ? 10  ASN A ND2 1 
ATOM 73   N N   . ILE A 1 12  ? 297.054 297.194 395.581 1.00 46.46  ? 11  ILE A N   1 
ATOM 74   C CA  . ILE A 1 12  ? 296.401 296.595 394.440 1.00 46.46  ? 11  ILE A CA  1 
ATOM 75   C C   . ILE A 1 12  ? 296.222 295.113 394.751 1.00 46.46  ? 11  ILE A C   1 
ATOM 76   O O   . ILE A 1 12  ? 296.872 294.559 395.641 1.00 46.46  ? 11  ILE A O   1 
ATOM 77   C CB  . ILE A 1 12  ? 297.246 296.845 393.164 1.00 46.46  ? 11  ILE A CB  1 
ATOM 78   C CG1 . ILE A 1 12  ? 296.476 296.649 391.874 1.00 46.46  ? 11  ILE A CG1 1 
ATOM 79   C CG2 . ILE A 1 12  ? 298.436 295.940 393.113 1.00 46.46  ? 11  ILE A CG2 1 
ATOM 80   C CD1 . ILE A 1 12  ? 297.290 297.055 390.680 1.00 46.46  ? 11  ILE A CD1 1 
ATOM 81   N N   . GLY A 1 13  ? 295.306 294.463 394.049 1.00 47.11  ? 12  GLY A N   1 
ATOM 82   C CA  . GLY A 1 13  ? 295.022 293.064 394.285 1.00 47.11  ? 12  GLY A CA  1 
ATOM 83   C C   . GLY A 1 13  ? 293.852 292.871 395.230 1.00 47.11  ? 12  GLY A C   1 
ATOM 84   O O   . GLY A 1 13  ? 293.327 293.811 395.829 1.00 47.11  ? 12  GLY A O   1 
ATOM 85   N N   . LYS A 1 14  ? 293.442 291.608 395.360 1.00 50.62  ? 13  LYS A N   1 
ATOM 86   C CA  . LYS A 1 14  ? 292.303 291.274 396.211 1.00 50.62  ? 13  LYS A CA  1 
ATOM 87   C C   . LYS A 1 14  ? 292.624 291.484 397.684 1.00 50.62  ? 13  LYS A C   1 
ATOM 88   O O   . LYS A 1 14  ? 291.859 292.127 398.409 1.00 50.62  ? 13  LYS A O   1 
ATOM 89   C CB  . LYS A 1 14  ? 291.867 289.834 395.961 1.00 50.62  ? 13  LYS A CB  1 
ATOM 90   C CG  . LYS A 1 14  ? 290.767 289.360 396.885 1.00 50.62  ? 13  LYS A CG  1 
ATOM 91   C CD  . LYS A 1 14  ? 289.481 290.117 396.641 1.00 50.62  ? 13  LYS A CD  1 
ATOM 92   C CE  . LYS A 1 14  ? 288.346 289.544 397.463 1.00 50.62  ? 13  LYS A CE  1 
ATOM 93   N NZ  . LYS A 1 14  ? 287.103 290.336 397.307 1.00 50.62  ? 13  LYS A NZ  1 
ATOM 94   N N   . ASP A 1 15  ? 293.747 290.933 398.148 1.00 56.12  ? 14  ASP A N   1 
ATOM 95   C CA  . ASP A 1 15  ? 294.177 291.168 399.522 1.00 56.12  ? 14  ASP A CA  1 
ATOM 96   C C   . ASP A 1 15  ? 294.620 292.608 399.739 1.00 56.12  ? 14  ASP A C   1 
ATOM 97   O O   . ASP A 1 15  ? 294.512 293.126 400.854 1.00 56.12  ? 14  ASP A O   1 
ATOM 98   C CB  . ASP A 1 15  ? 295.296 290.196 399.887 1.00 56.12  ? 14  ASP A CB  1 
ATOM 99   C CG  . ASP A 1 15  ? 296.434 290.206 398.882 1.00 56.12  ? 14  ASP A CG  1 
ATOM 100  O OD1 . ASP A 1 15  ? 296.316 290.870 397.835 1.00 56.12  ? 14  ASP A OD1 1 
ATOM 101  O OD2 . ASP A 1 15  ? 297.458 289.541 399.141 1.00 56.12  ? 14  ASP A OD2 1 
ATOM 102  N N   . GLY A 1 16  ? 295.113 293.264 398.694 1.00 54.24  ? 15  GLY A N   1 
ATOM 103  C CA  . GLY A 1 16  ? 295.501 294.652 398.793 1.00 54.24  ? 15  GLY A CA  1 
ATOM 104  C C   . GLY A 1 16  ? 296.900 294.890 399.301 1.00 54.24  ? 15  GLY A C   1 
ATOM 105  O O   . GLY A 1 16  ? 297.152 295.924 399.927 1.00 54.24  ? 15  GLY A O   1 
ATOM 106  N N   . LYS A 1 17  ? 297.823 293.965 399.054 1.00 54.28  ? 16  LYS A N   1 
ATOM 107  C CA  . LYS A 1 17  ? 299.197 294.095 399.508 1.00 54.28  ? 16  LYS A CA  1 
ATOM 108  C C   . LYS A 1 17  ? 300.190 294.162 398.365 1.00 54.28  ? 16  LYS A C   1 
ATOM 109  O O   . LYS A 1 17  ? 301.390 294.304 398.613 1.00 54.28  ? 16  LYS A O   1 
ATOM 110  C CB  . LYS A 1 17  ? 299.562 292.924 400.423 1.00 54.28  ? 16  LYS A CB  1 
ATOM 111  C CG  . LYS A 1 17  ? 298.815 292.905 401.735 1.00 54.28  ? 16  LYS A CG  1 
ATOM 112  C CD  . LYS A 1 17  ? 299.336 291.801 402.631 1.00 54.28  ? 16  LYS A CD  1 
ATOM 113  C CE  . LYS A 1 17  ? 298.872 290.444 402.144 1.00 54.28  ? 16  LYS A CE  1 
ATOM 114  N NZ  . LYS A 1 17  ? 299.288 289.357 403.068 1.00 54.28  ? 16  LYS A NZ  1 
ATOM 115  N N   . GLN A 1 18  ? 299.731 294.060 397.128 1.00 50.24  ? 17  GLN A N   1 
ATOM 116  C CA  . GLN A 1 18  ? 300.621 293.982 395.986 1.00 50.24  ? 17  GLN A CA  1 
ATOM 117  C C   . GLN A 1 18  ? 300.944 295.381 395.472 1.00 50.24  ? 17  GLN A C   1 
ATOM 118  O O   . GLN A 1 18  ? 300.344 296.375 395.875 1.00 50.24  ? 17  GLN A O   1 
ATOM 119  C CB  . GLN A 1 18  ? 299.977 293.140 394.892 1.00 50.24  ? 17  GLN A CB  1 
ATOM 120  C CG  . GLN A 1 18  ? 299.675 291.724 395.309 1.00 50.24  ? 17  GLN A CG  1 
ATOM 121  C CD  . GLN A 1 18  ? 298.910 290.971 394.252 1.00 50.24  ? 17  GLN A CD  1 
ATOM 122  O OE1 . GLN A 1 18  ? 298.565 291.525 393.213 1.00 50.24  ? 17  GLN A OE1 1 
ATOM 123  N NE2 . GLN A 1 18  ? 298.623 289.706 394.515 1.00 50.24  ? 17  GLN A NE2 1 
ATOM 124  N N   . THR A 1 19  ? 301.920 295.451 394.571 1.00 49.36  ? 18  THR A N   1 
ATOM 125  C CA  . THR A 1 19  ? 302.226 296.666 393.835 1.00 49.36  ? 18  THR A CA  1 
ATOM 126  C C   . THR A 1 19  ? 302.275 296.343 392.352 1.00 49.36  ? 18  THR A C   1 
ATOM 127  O O   . THR A 1 19  ? 302.405 295.186 391.949 1.00 49.36  ? 18  THR A O   1 
ATOM 128  C CB  . THR A 1 19  ? 303.561 297.294 394.251 1.00 49.36  ? 18  THR A CB  1 
ATOM 129  O OG1 . THR A 1 19  ? 304.619 296.354 394.037 1.00 49.36  ? 18  THR A OG1 1 
ATOM 130  C CG2 . THR A 1 19  ? 303.543 297.723 395.706 1.00 49.36  ? 18  THR A CG2 1 
ATOM 131  N N   . LEU A 1 20  ? 302.164 297.387 391.541 1.00 45.65  ? 19  LEU A N   1 
ATOM 132  C CA  . LEU A 1 20  ? 302.306 297.277 390.094 1.00 45.65  ? 19  LEU A CA  1 
ATOM 133  C C   . LEU A 1 20  ? 302.956 298.561 389.612 1.00 45.65  ? 19  LEU A C   1 
ATOM 134  O O   . LEU A 1 20  ? 302.301 299.602 389.551 1.00 45.65  ? 19  LEU A O   1 
ATOM 135  C CB  . LEU A 1 20  ? 300.964 297.059 389.405 1.00 45.65  ? 19  LEU A CB  1 
ATOM 136  C CG  . LEU A 1 20  ? 301.064 296.985 387.886 1.00 45.65  ? 19  LEU A CG  1 
ATOM 137  C CD1 . LEU A 1 20  ? 301.910 295.806 387.472 1.00 45.65  ? 19  LEU A CD1 1 
ATOM 138  C CD2 . LEU A 1 20  ? 299.695 296.906 387.262 1.00 45.65  ? 19  LEU A CD2 1 
ATOM 139  N N   . VAL A 1 21  ? 304.233 298.494 389.295 1.00 47.42  ? 20  VAL A N   1 
ATOM 140  C CA  . VAL A 1 21  ? 304.997 299.652 388.850 1.00 47.42  ? 20  VAL A CA  1 
ATOM 141  C C   . VAL A 1 21  ? 305.005 299.695 387.332 1.00 47.42  ? 20  VAL A C   1 
ATOM 142  O O   . VAL A 1 21  ? 305.096 298.659 386.666 1.00 47.42  ? 20  VAL A O   1 
ATOM 143  C CB  . VAL A 1 21  ? 306.417 299.619 389.435 1.00 47.42  ? 20  VAL A CB  1 
ATOM 144  C CG1 . VAL A 1 21  ? 306.371 300.023 390.877 1.00 47.42  ? 20  VAL A CG1 1 
ATOM 145  C CG2 . VAL A 1 21  ? 306.938 298.212 389.390 1.00 47.42  ? 20  VAL A CG2 1 
ATOM 146  N N   . LEU A 1 22  ? 304.894 300.899 386.780 1.00 44.18  ? 21  LEU A N   1 
ATOM 147  C CA  . LEU A 1 22  ? 304.619 301.094 385.363 1.00 44.18  ? 21  LEU A CA  1 
ATOM 148  C C   . LEU A 1 22  ? 305.525 302.176 384.803 1.00 44.18  ? 21  LEU A C   1 
ATOM 149  O O   . LEU A 1 22  ? 305.454 303.326 385.240 1.00 44.18  ? 21  LEU A O   1 
ATOM 150  C CB  . LEU A 1 22  ? 303.155 301.477 385.147 1.00 44.18  ? 21  LEU A CB  1 
ATOM 151  C CG  . LEU A 1 22  ? 302.076 300.430 385.380 1.00 44.18  ? 21  LEU A CG  1 
ATOM 152  C CD1 . LEU A 1 22  ? 300.732 301.085 385.375 1.00 44.18  ? 21  LEU A CD1 1 
ATOM 153  C CD2 . LEU A 1 22  ? 302.138 299.399 384.284 1.00 44.18  ? 21  LEU A CD2 1 
ATOM 154  N N   . ASN A 1 23  ? 306.356 301.816 383.829 1.00 43.87  ? 22  ASN A N   1 
ATOM 155  C CA  . ASN A 1 23  ? 307.219 302.784 383.168 1.00 43.87  ? 22  ASN A CA  1 
ATOM 156  C C   . ASN A 1 23  ? 306.581 303.281 381.882 1.00 43.87  ? 22  ASN A C   1 
ATOM 157  O O   . ASN A 1 23  ? 305.904 302.513 381.195 1.00 43.87  ? 22  ASN A O   1 
ATOM 158  C CB  . ASN A 1 23  ? 308.584 302.179 382.845 1.00 43.87  ? 22  ASN A CB  1 
ATOM 159  C CG  . ASN A 1 23  ? 309.385 301.870 384.077 1.00 43.87  ? 22  ASN A CG  1 
ATOM 160  O OD1 . ASN A 1 23  ? 309.795 300.737 384.288 1.00 43.87  ? 22  ASN A OD1 1 
ATOM 161  N ND2 . ASN A 1 23  ? 309.598 302.875 384.911 1.00 43.87  ? 22  ASN A ND2 1 
ATOM 162  N N   . PRO A 1 24  ? 306.784 304.548 381.526 1.00 42.66  ? 23  PRO A N   1 
ATOM 163  C CA  . PRO A 1 24  ? 306.175 305.073 380.303 1.00 42.66  ? 23  PRO A CA  1 
ATOM 164  C C   . PRO A 1 24  ? 306.848 304.533 379.059 1.00 42.66  ? 23  PRO A C   1 
ATOM 165  O O   . PRO A 1 24  ? 308.047 304.256 379.041 1.00 42.66  ? 23  PRO A O   1 
ATOM 166  C CB  . PRO A 1 24  ? 306.385 306.580 380.425 1.00 42.66  ? 23  PRO A CB  1 
ATOM 167  C CG  . PRO A 1 24  ? 307.582 306.708 381.272 1.00 42.66  ? 23  PRO A CG  1 
ATOM 168  C CD  . PRO A 1 24  ? 307.523 305.594 382.253 1.00 42.66  ? 23  PRO A CD  1 
ATOM 169  N N   . ARG A 1 25  ? 306.050 304.378 378.009 1.00 40.22  ? 24  ARG A N   1 
ATOM 170  C CA  . ARG A 1 25  ? 306.522 303.841 376.742 1.00 40.22  ? 24  ARG A CA  1 
ATOM 171  C C   . ARG A 1 25  ? 306.289 304.810 375.592 1.00 40.22  ? 24  ARG A C   1 
ATOM 172  O O   . ARG A 1 25  ? 306.284 304.398 374.432 1.00 40.22  ? 24  ARG A O   1 
ATOM 173  C CB  . ARG A 1 25  ? 305.855 302.498 376.455 1.00 40.22  ? 24  ARG A CB  1 
ATOM 174  C CG  . ARG A 1 25  ? 306.214 301.417 377.453 1.00 40.22  ? 24  ARG A CG  1 
ATOM 175  C CD  . ARG A 1 25  ? 307.634 300.971 377.247 1.00 40.22  ? 24  ARG A CD  1 
ATOM 176  N NE  . ARG A 1 25  ? 307.793 300.463 375.893 1.00 40.22  ? 24  ARG A NE  1 
ATOM 177  C CZ  . ARG A 1 25  ? 307.592 299.201 375.540 1.00 40.22  ? 24  ARG A CZ  1 
ATOM 178  N NH1 . ARG A 1 25  ? 307.250 298.305 376.448 1.00 40.22  ? 24  ARG A NH1 1 
ATOM 179  N NH2 . ARG A 1 25  ? 307.748 298.829 374.281 1.00 40.22  ? 24  ARG A NH2 1 
ATOM 180  N N   . GLY A 1 26  ? 306.081 306.088 375.893 1.00 39.15  ? 25  GLY A N   1 
ATOM 181  C CA  . GLY A 1 26  ? 305.961 307.108 374.869 1.00 39.15  ? 25  GLY A CA  1 
ATOM 182  C C   . GLY A 1 26  ? 304.630 307.147 374.150 1.00 39.15  ? 25  GLY A C   1 
ATOM 183  O O   . GLY A 1 26  ? 303.964 306.121 374.006 1.00 39.15  ? 25  GLY A O   1 
ATOM 184  N N   . VAL A 1 27  ? 304.232 308.326 373.681 1.00 39.30  ? 26  VAL A N   1 
ATOM 185  C CA  . VAL A 1 27  ? 302.985 308.467 372.944 1.00 39.30  ? 26  VAL A CA  1 
ATOM 186  C C   . VAL A 1 27  ? 303.175 307.958 371.526 1.00 39.30  ? 26  VAL A C   1 
ATOM 187  O O   . VAL A 1 27  ? 304.295 307.685 371.087 1.00 39.30  ? 26  VAL A O   1 
ATOM 188  C CB  . VAL A 1 27  ? 302.479 309.918 372.928 1.00 39.30  ? 26  VAL A CB  1 
ATOM 189  C CG1 . VAL A 1 27  ? 302.261 310.405 374.328 1.00 39.30  ? 26  VAL A CG1 1 
ATOM 190  C CG2 . VAL A 1 27  ? 303.456 310.794 372.199 1.00 39.30  ? 26  VAL A CG2 1 
ATOM 191  N N   . ASN A 1 28  ? 302.070 307.828 370.810 1.00 41.60  ? 27  ASN A N   1 
ATOM 192  C CA  . ASN A 1 28  ? 302.031 307.302 369.464 1.00 41.60  ? 27  ASN A CA  1 
ATOM 193  C C   . ASN A 1 28  ? 301.656 308.427 368.516 1.00 41.60  ? 27  ASN A C   1 
ATOM 194  O O   . ASN A 1 28  ? 300.567 308.991 368.667 1.00 41.60  ? 27  ASN A O   1 
ATOM 195  C CB  . ASN A 1 28  ? 300.996 306.181 369.407 1.00 41.60  ? 27  ASN A CB  1 
ATOM 196  C CG  . ASN A 1 28  ? 301.061 305.373 368.139 1.00 41.60  ? 27  ASN A CG  1 
ATOM 197  O OD1 . ASN A 1 28  ? 301.884 305.618 367.265 1.00 41.60  ? 27  ASN A OD1 1 
ATOM 198  N ND2 . ASN A 1 28  ? 300.183 304.391 368.031 1.00 41.60  ? 27  ASN A ND2 1 
ATOM 199  N N   . PRO A 1 29  ? 302.489 308.800 367.539 1.00 43.15  ? 28  PRO A N   1 
ATOM 200  C CA  . PRO A 1 29  ? 302.119 309.906 366.643 1.00 43.15  ? 28  PRO A CA  1 
ATOM 201  C C   . PRO A 1 29  ? 300.978 309.583 365.698 1.00 43.15  ? 28  PRO A C   1 
ATOM 202  O O   . PRO A 1 29  ? 300.408 310.508 365.113 1.00 43.15  ? 28  PRO A O   1 
ATOM 203  C CB  . PRO A 1 29  ? 303.410 310.170 365.864 1.00 43.15  ? 28  PRO A CB  1 
ATOM 204  C CG  . PRO A 1 29  ? 304.124 308.883 365.893 1.00 43.15  ? 28  PRO A CG  1 
ATOM 205  C CD  . PRO A 1 29  ? 303.827 308.275 367.227 1.00 43.15  ? 28  PRO A CD  1 
ATOM 206  N N   . THR A 1 30  ? 300.628 308.310 365.528 1.00 45.58  ? 29  THR A N   1 
ATOM 207  C CA  . THR A 1 30  ? 299.501 307.963 364.672 1.00 45.58  ? 29  THR A CA  1 
ATOM 208  C C   . THR A 1 30  ? 298.177 308.306 365.344 1.00 45.58  ? 29  THR A C   1 
ATOM 209  O O   . THR A 1 30  ? 297.268 308.846 364.703 1.00 45.58  ? 29  THR A O   1 
ATOM 210  C CB  . THR A 1 30  ? 299.559 306.477 364.323 1.00 45.58  ? 29  THR A CB  1 
ATOM 211  O OG1 . THR A 1 30  ? 300.818 306.184 363.709 1.00 45.58  ? 29  THR A OG1 1 
ATOM 212  C CG2 . THR A 1 30  ? 298.450 306.104 363.359 1.00 45.58  ? 29  THR A CG2 1 
ATOM 213  N N   . ASN A 1 31  ? 298.062 308.034 366.642 1.00 45.39  ? 30  ASN A N   1 
ATOM 214  C CA  . ASN A 1 31  ? 296.800 308.181 367.351 1.00 45.39  ? 30  ASN A CA  1 
ATOM 215  C C   . ASN A 1 31  ? 296.843 309.104 368.555 1.00 45.39  ? 30  ASN A C   1 
ATOM 216  O O   . ASN A 1 31  ? 295.775 309.518 369.015 1.00 45.39  ? 30  ASN A O   1 
ATOM 217  C CB  . ASN A 1 31  ? 296.293 306.814 367.824 1.00 45.39  ? 30  ASN A CB  1 
ATOM 218  C CG  . ASN A 1 31  ? 295.871 305.929 366.688 1.00 45.39  ? 30  ASN A CG  1 
ATOM 219  O OD1 . ASN A 1 31  ? 295.244 306.382 365.732 1.00 45.39  ? 30  ASN A OD1 1 
ATOM 220  N ND2 . ASN A 1 31  ? 296.211 304.651 366.780 1.00 45.39  ? 30  ASN A ND2 1 
ATOM 221  N N   . GLY A 1 32  ? 298.012 309.438 369.086 1.00 41.56  ? 31  GLY A N   1 
ATOM 222  C CA  . GLY A 1 32  ? 298.065 310.250 370.286 1.00 41.56  ? 31  GLY A CA  1 
ATOM 223  C C   . GLY A 1 32  ? 297.704 309.492 371.539 1.00 41.56  ? 31  GLY A C   1 
ATOM 224  O O   . GLY A 1 32  ? 297.037 310.042 372.421 1.00 41.56  ? 31  GLY A O   1 
ATOM 225  N N   . VAL A 1 33  ? 298.128 308.239 371.643 1.00 36.89  ? 32  VAL A N   1 
ATOM 226  C CA  . VAL A 1 33  ? 297.762 307.360 372.745 1.00 36.89  ? 32  VAL A CA  1 
ATOM 227  C C   . VAL A 1 33  ? 298.997 307.149 373.600 1.00 36.89  ? 32  VAL A C   1 
ATOM 228  O O   . VAL A 1 33  ? 299.966 306.524 373.156 1.00 36.89  ? 32  VAL A O   1 
ATOM 229  C CB  . VAL A 1 33  ? 297.222 306.017 372.244 1.00 36.89  ? 32  VAL A CB  1 
ATOM 230  C CG1 . VAL A 1 33  ? 296.945 305.106 373.408 1.00 36.89  ? 32  VAL A CG1 1 
ATOM 231  C CG2 . VAL A 1 33  ? 295.987 306.212 371.423 1.00 36.89  ? 32  VAL A CG2 1 
ATOM 232  N N   . ALA A 1 34  ? 298.968 307.657 374.826 1.00 35.18  ? 33  ALA A N   1 
ATOM 233  C CA  . ALA A 1 34  ? 300.036 307.373 375.768 1.00 35.18  ? 33  ALA A CA  1 
ATOM 234  C C   . ALA A 1 34  ? 299.986 305.910 376.177 1.00 35.18  ? 33  ALA A C   1 
ATOM 235  O O   . ALA A 1 34  ? 298.922 305.302 376.232 1.00 35.18  ? 33  ALA A O   1 
ATOM 236  C CB  . ALA A 1 34  ? 299.919 308.262 376.996 1.00 35.18  ? 33  ALA A CB  1 
ATOM 237  N N   . SER A 1 35  ? 301.153 305.335 376.441 1.00 37.40  ? 34  SER A N   1 
ATOM 238  C CA  . SER A 1 35  ? 301.266 303.920 376.755 1.00 37.40  ? 34  SER A CA  1 
ATOM 239  C C   . SER A 1 35  ? 302.167 303.729 377.963 1.00 37.40  ? 34  SER A C   1 
ATOM 240  O O   . SER A 1 35  ? 303.077 304.522 378.206 1.00 37.40  ? 34  SER A O   1 
ATOM 241  C CB  . SER A 1 35  ? 301.830 303.136 375.580 1.00 37.40  ? 34  SER A CB  1 
ATOM 242  O OG  . SER A 1 35  ? 300.976 303.231 374.458 1.00 37.40  ? 34  SER A OG  1 
ATOM 243  N N   . LEU A 1 36  ? 301.889 302.684 378.737 1.00 39.28  ? 35  LEU A N   1 
ATOM 244  C CA  . LEU A 1 36  ? 302.725 302.304 379.865 1.00 39.28  ? 35  LEU A CA  1 
ATOM 245  C C   . LEU A 1 36  ? 302.844 300.788 379.868 1.00 39.28  ? 35  LEU A C   1 
ATOM 246  O O   . LEU A 1 36  ? 302.067 300.091 379.215 1.00 39.28  ? 35  LEU A O   1 
ATOM 247  C CB  . LEU A 1 36  ? 302.173 302.799 381.208 1.00 39.28  ? 35  LEU A CB  1 
ATOM 248  C CG  . LEU A 1 36  ? 302.233 304.288 381.563 1.00 39.28  ? 35  LEU A CG  1 
ATOM 249  C CD1 . LEU A 1 36  ? 301.066 305.058 380.992 1.00 39.28  ? 35  LEU A CD1 1 
ATOM 250  C CD2 . LEU A 1 36  ? 302.296 304.492 383.050 1.00 39.28  ? 35  LEU A CD2 1 
ATOM 251  N N   . SER A 1 37  ? 303.842 300.279 380.583 1.00 43.48  ? 36  SER A N   1 
ATOM 252  C CA  . SER A 1 37  ? 304.080 298.843 380.652 1.00 43.48  ? 36  SER A CA  1 
ATOM 253  C C   . SER A 1 37  ? 304.767 298.512 381.967 1.00 43.48  ? 36  SER A C   1 
ATOM 254  O O   . SER A 1 37  ? 305.267 299.393 382.661 1.00 43.48  ? 36  SER A O   1 
ATOM 255  C CB  . SER A 1 37  ? 304.919 298.350 379.476 1.00 43.48  ? 36  SER A CB  1 
ATOM 256  O OG  . SER A 1 37  ? 304.210 298.481 378.260 1.00 43.48  ? 36  SER A OG  1 
ATOM 257  N N   . GLN A 1 38  ? 304.791 297.223 382.295 1.00 47.58  ? 37  GLN A N   1 
ATOM 258  C CA  . GLN A 1 38  ? 305.282 296.768 383.587 1.00 47.58  ? 37  GLN A CA  1 
ATOM 259  C C   . GLN A 1 38  ? 306.797 296.934 383.673 1.00 47.58  ? 37  GLN A C   1 
ATOM 260  O O   . GLN A 1 38  ? 307.513 296.825 382.676 1.00 47.58  ? 37  GLN A O   1 
ATOM 261  C CB  . GLN A 1 38  ? 304.906 295.302 383.795 1.00 47.58  ? 37  GLN A CB  1 
ATOM 262  C CG  . GLN A 1 38  ? 305.062 294.785 385.203 1.00 47.58  ? 37  GLN A CG  1 
ATOM 263  C CD  . GLN A 1 38  ? 304.819 293.307 385.288 1.00 47.58  ? 37  GLN A CD  1 
ATOM 264  O OE1 . GLN A 1 38  ? 304.639 292.642 384.272 1.00 47.58  ? 37  GLN A OE1 1 
ATOM 265  N NE2 . GLN A 1 38  ? 304.808 292.779 386.501 1.00 47.58  ? 37  GLN A NE2 1 
ATOM 266  N N   . ALA A 1 39  ? 307.286 297.216 384.877 1.00 48.63  ? 38  ALA A N   1 
ATOM 267  C CA  . ALA A 1 39  ? 308.708 297.471 385.089 1.00 48.63  ? 38  ALA A CA  1 
ATOM 268  C C   . ALA A 1 39  ? 309.436 296.146 385.211 1.00 48.63  ? 38  ALA A C   1 
ATOM 269  O O   . ALA A 1 39  ? 309.497 295.549 386.286 1.00 48.63  ? 38  ALA A O   1 
ATOM 270  C CB  . ALA A 1 39  ? 308.929 298.328 386.325 1.00 48.63  ? 38  ALA A CB  1 
ATOM 271  N N   . GLY A 1 40  ? 309.973 295.676 384.096 1.00 49.10  ? 39  GLY A N   1 
ATOM 272  C CA  . GLY A 1 40  ? 310.809 294.498 384.070 1.00 49.10  ? 39  GLY A CA  1 
ATOM 273  C C   . GLY A 1 40  ? 310.012 293.297 383.627 1.00 49.10  ? 39  GLY A C   1 
ATOM 274  O O   . GLY A 1 40  ? 309.405 292.604 384.449 1.00 49.10  ? 39  GLY A O   1 
ATOM 275  N N   . ALA A 1 41  ? 310.065 293.032 382.328 1.00 48.59  ? 40  ALA A N   1 
ATOM 276  C CA  . ALA A 1 41  ? 309.386 291.959 381.615 1.00 48.59  ? 40  ALA A CA  1 
ATOM 277  C C   . ALA A 1 41  ? 309.830 292.099 380.170 1.00 48.59  ? 40  ALA A C   1 
ATOM 278  O O   . ALA A 1 41  ? 310.268 293.169 379.740 1.00 48.59  ? 40  ALA A O   1 
ATOM 279  C CB  . ALA A 1 41  ? 307.864 292.016 381.699 1.00 48.59  ? 40  ALA A CB  1 
ATOM 280  N N   . VAL A 1 42  ? 309.704 291.015 379.419 1.00 48.18  ? 41  VAL A N   1 
ATOM 281  C CA  . VAL A 1 42  ? 310.047 291.064 378.006 1.00 48.18  ? 41  VAL A CA  1 
ATOM 282  C C   . VAL A 1 42  ? 308.875 291.733 377.298 1.00 48.18  ? 41  VAL A C   1 
ATOM 283  O O   . VAL A 1 42  ? 307.771 291.771 377.857 1.00 48.18  ? 41  VAL A O   1 
ATOM 284  C CB  . VAL A 1 42  ? 310.350 289.661 377.462 1.00 48.18  ? 41  VAL A CB  1 
ATOM 285  C CG1 . VAL A 1 42  ? 311.519 289.067 378.216 1.00 48.18  ? 41  VAL A CG1 1 
ATOM 286  C CG2 . VAL A 1 42  ? 309.152 288.774 377.588 1.00 48.18  ? 41  VAL A CG2 1 
ATOM 287  N N   . PRO A 1 43  ? 309.072 292.325 376.120 1.00 48.59  ? 42  PRO A N   1 
ATOM 288  C CA  . PRO A 1 43  ? 307.928 292.794 375.336 1.00 48.59  ? 42  PRO A CA  1 
ATOM 289  C C   . PRO A 1 43  ? 307.025 291.639 374.935 1.00 48.59  ? 42  PRO A C   1 
ATOM 290  O O   . PRO A 1 43  ? 307.462 290.492 374.826 1.00 48.59  ? 42  PRO A O   1 
ATOM 291  C CB  . PRO A 1 43  ? 308.581 293.444 374.117 1.00 48.59  ? 42  PRO A CB  1 
ATOM 292  C CG  . PRO A 1 43  ? 309.906 293.866 374.606 1.00 48.59  ? 42  PRO A CG  1 
ATOM 293  C CD  . PRO A 1 43  ? 310.343 292.815 375.563 1.00 48.59  ? 42  PRO A CD  1 
ATOM 294  N N   . ALA A 1 44  ? 305.743 291.963 374.764 1.00 50.16  ? 43  ALA A N   1 
ATOM 295  C CA  . ALA A 1 44  ? 304.652 291.028 374.474 1.00 50.16  ? 43  ALA A CA  1 
ATOM 296  C C   . ALA A 1 44  ? 304.492 289.947 375.539 1.00 50.16  ? 43  ALA A C   1 
ATOM 297  O O   . ALA A 1 44  ? 304.008 288.853 375.242 1.00 50.16  ? 43  ALA A O   1 
ATOM 298  C CB  . ALA A 1 44  ? 304.792 290.387 373.085 1.00 50.16  ? 43  ALA A CB  1 
ATOM 299  N N   . LEU A 1 45  ? 304.915 290.215 376.775 1.00 50.10  ? 44  LEU A N   1 
ATOM 300  C CA  . LEU A 1 45  ? 304.538 289.389 377.914 1.00 50.10  ? 44  LEU A CA  1 
ATOM 301  C C   . LEU A 1 45  ? 304.372 290.261 379.159 1.00 50.10  ? 44  LEU A C   1 
ATOM 302  O O   . LEU A 1 45  ? 304.695 289.841 380.274 1.00 50.10  ? 44  LEU A O   1 
ATOM 303  C CB  . LEU A 1 45  ? 305.558 288.266 378.117 1.00 50.10  ? 44  LEU A CB  1 
ATOM 304  C CG  . LEU A 1 45  ? 305.334 287.017 378.971 1.00 50.10  ? 44  LEU A CG  1 
ATOM 305  C CD1 . LEU A 1 45  ? 304.182 286.209 378.444 1.00 50.10  ? 44  LEU A CD1 1 
ATOM 306  C CD2 . LEU A 1 45  ? 306.596 286.203 378.982 1.00 50.10  ? 44  LEU A CD2 1 
ATOM 307  N N   . GLU A 1 46  ? 303.906 291.494 378.994 1.00 49.49  ? 45  GLU A N   1 
ATOM 308  C CA  . GLU A 1 46  ? 303.848 292.423 380.111 1.00 49.49  ? 45  GLU A CA  1 
ATOM 309  C C   . GLU A 1 46  ? 302.475 293.070 380.187 1.00 49.49  ? 45  GLU A C   1 
ATOM 310  O O   . GLU A 1 46  ? 301.672 292.993 379.256 1.00 49.49  ? 45  GLU A O   1 
ATOM 311  C CB  . GLU A 1 46  ? 304.921 293.508 379.998 1.00 49.49  ? 45  GLU A CB  1 
ATOM 312  C CG  . GLU A 1 46  ? 304.592 294.637 379.039 1.00 49.49  ? 45  GLU A CG  1 
ATOM 313  C CD  . GLU A 1 46  ? 304.993 294.374 377.609 1.00 49.49  ? 45  GLU A CD  1 
ATOM 314  O OE1 . GLU A 1 46  ? 305.258 293.210 377.255 1.00 49.49  ? 45  GLU A OE1 1 
ATOM 315  O OE2 . GLU A 1 46  ? 305.044 295.347 376.830 1.00 49.49  ? 45  GLU A OE2 1 
ATOM 316  N N   . LYS A 1 47  ? 302.224 293.721 381.317 1.00 45.23  ? 46  LYS A N   1 
ATOM 317  C CA  . LYS A 1 47  ? 300.940 294.351 381.574 1.00 45.23  ? 46  LYS A CA  1 
ATOM 318  C C   . LYS A 1 47  ? 300.924 295.757 380.995 1.00 45.23  ? 46  LYS A C   1 
ATOM 319  O O   . LYS A 1 47  ? 301.793 296.569 381.315 1.00 45.23  ? 46  LYS A O   1 
ATOM 320  C CB  . LYS A 1 47  ? 300.684 294.401 383.075 1.00 45.23  ? 46  LYS A CB  1 
ATOM 321  C CG  . LYS A 1 47  ? 300.615 293.043 383.730 1.00 45.23  ? 46  LYS A CG  1 
ATOM 322  C CD  . LYS A 1 47  ? 300.165 293.159 385.172 1.00 45.23  ? 46  LYS A CD  1 
ATOM 323  C CE  . LYS A 1 47  ? 299.873 291.800 385.765 1.00 45.23  ? 46  LYS A CE  1 
ATOM 324  N NZ  . LYS A 1 47  ? 301.105 290.994 385.904 1.00 45.23  ? 46  LYS A NZ  1 
ATOM 325  N N   . ARG A 1 48  ? 299.929 296.060 380.167 1.00 42.98  ? 47  ARG A N   1 
ATOM 326  C CA  . ARG A 1 48  ? 299.886 297.317 379.434 1.00 42.98  ? 47  ARG A CA  1 
ATOM 327  C C   . ARG A 1 48  ? 298.752 298.204 379.921 1.00 42.98  ? 47  ARG A C   1 
ATOM 328  O O   . ARG A 1 48  ? 297.680 297.716 380.279 1.00 42.98  ? 47  ARG A O   1 
ATOM 329  C CB  . ARG A 1 48  ? 299.731 297.075 377.940 1.00 42.98  ? 47  ARG A CB  1 
ATOM 330  C CG  . ARG A 1 48  ? 300.961 296.485 377.305 1.00 42.98  ? 47  ARG A CG  1 
ATOM 331  C CD  . ARG A 1 48  ? 300.776 296.288 375.822 1.00 42.98  ? 47  ARG A CD  1 
ATOM 332  N NE  . ARG A 1 48  ? 301.949 295.673 375.211 1.00 42.98  ? 47  ARG A NE  1 
ATOM 333  C CZ  . ARG A 1 48  ? 302.029 295.325 373.932 1.00 42.98  ? 47  ARG A CZ  1 
ATOM 334  N NH1 . ARG A 1 48  ? 301.001 295.530 373.121 1.00 42.98  ? 47  ARG A NH1 1 
ATOM 335  N NH2 . ARG A 1 48  ? 303.137 294.769 373.464 1.00 42.98  ? 47  ARG A NH2 1 
ATOM 336  N N   . VAL A 1 49  ? 299.009 299.511 379.946 1.00 36.13  ? 48  VAL A N   1 
ATOM 337  C CA  . VAL A 1 49  ? 298.014 300.533 380.252 1.00 36.13  ? 48  VAL A CA  1 
ATOM 338  C C   . VAL A 1 49  ? 298.128 301.623 379.198 1.00 36.13  ? 48  VAL A C   1 
ATOM 339  O O   . VAL A 1 49  ? 299.216 302.162 378.982 1.00 36.13  ? 48  VAL A O   1 
ATOM 340  C CB  . VAL A 1 49  ? 298.214 301.147 381.650 1.00 36.13  ? 48  VAL A CB  1 
ATOM 341  C CG1 . VAL A 1 49  ? 297.189 302.233 381.892 1.00 36.13  ? 48  VAL A CG1 1 
ATOM 342  C CG2 . VAL A 1 49  ? 298.141 300.104 382.738 1.00 36.13  ? 48  VAL A CG2 1 
ATOM 343  N N   . THR A 1 50  ? 297.015 301.956 378.545 1.00 34.21  ? 49  THR A N   1 
ATOM 344  C CA  . THR A 1 50  ? 296.987 303.047 377.582 1.00 34.21  ? 49  THR A CA  1 
ATOM 345  C C   . THR A 1 50  ? 295.963 304.093 378.004 1.00 34.21  ? 49  THR A C   1 
ATOM 346  O O   . THR A 1 50  ? 295.054 303.810 378.785 1.00 34.21  ? 49  THR A O   1 
ATOM 347  C CB  . THR A 1 50  ? 296.656 302.561 376.170 1.00 34.21  ? 49  THR A CB  1 
ATOM 348  O OG1 . THR A 1 50  ? 295.325 302.046 376.145 1.00 34.21  ? 49  THR A OG1 1 
ATOM 349  C CG2 . THR A 1 50  ? 297.610 301.476 375.731 1.00 34.21  ? 49  THR A CG2 1 
ATOM 350  N N   . VAL A 1 51  ? 296.127 305.309 377.485 1.00 33.20  ? 50  VAL A N   1 
ATOM 351  C CA  . VAL A 1 51  ? 295.247 306.433 377.794 1.00 33.20  ? 50  VAL A CA  1 
ATOM 352  C C   . VAL A 1 51  ? 295.324 307.432 376.642 1.00 33.20  ? 50  VAL A C   1 
ATOM 353  O O   . VAL A 1 51  ? 296.393 307.659 376.072 1.00 33.20  ? 50  VAL A O   1 
ATOM 354  C CB  . VAL A 1 51  ? 295.601 307.053 379.170 1.00 33.20  ? 50  VAL A CB  1 
ATOM 355  C CG1 . VAL A 1 51  ? 297.030 307.522 379.229 1.00 33.20  ? 50  VAL A CG1 1 
ATOM 356  C CG2 . VAL A 1 51  ? 294.658 308.185 379.535 1.00 33.20  ? 50  VAL A CG2 1 
ATOM 357  N N   . SER A 1 52  ? 294.175 307.985 376.256 1.00 33.90  ? 51  SER A N   1 
ATOM 358  C CA  . SER A 1 52  ? 294.116 308.883 375.107 1.00 33.90  ? 51  SER A CA  1 
ATOM 359  C C   . SER A 1 52  ? 292.954 309.846 375.264 1.00 33.90  ? 51  SER A C   1 
ATOM 360  O O   . SER A 1 52  ? 291.840 309.424 375.577 1.00 33.90  ? 51  SER A O   1 
ATOM 361  C CB  . SER A 1 52  ? 293.965 308.100 373.812 1.00 33.90  ? 51  SER A CB  1 
ATOM 362  O OG  . SER A 1 52  ? 292.710 307.462 373.752 1.00 33.90  ? 51  SER A OG  1 
ATOM 363  N N   . VAL A 1 53  ? 293.210 311.127 375.016 1.00 37.55  ? 52  VAL A N   1 
ATOM 364  C CA  . VAL A 1 53  ? 292.234 312.198 375.174 1.00 37.55  ? 52  VAL A CA  1 
ATOM 365  C C   . VAL A 1 53  ? 291.943 312.784 373.800 1.00 37.55  ? 52  VAL A C   1 
ATOM 366  O O   . VAL A 1 53  ? 292.874 313.098 373.050 1.00 37.55  ? 52  VAL A O   1 
ATOM 367  C CB  . VAL A 1 53  ? 292.759 313.278 376.133 1.00 37.55  ? 52  VAL A CB  1 
ATOM 368  C CG1 . VAL A 1 53  ? 291.772 314.408 376.251 1.00 37.55  ? 52  VAL A CG1 1 
ATOM 369  C CG2 . VAL A 1 53  ? 293.043 312.686 377.488 1.00 37.55  ? 52  VAL A CG2 1 
ATOM 370  N N   . SER A 1 54  ? 290.665 312.921 373.462 1.00 41.01  ? 53  SER A N   1 
ATOM 371  C CA  . SER A 1 54  ? 290.261 313.475 372.180 1.00 41.01  ? 53  SER A CA  1 
ATOM 372  C C   . SER A 1 54  ? 289.578 314.822 372.371 1.00 41.01  ? 53  SER A C   1 
ATOM 373  O O   . SER A 1 54  ? 288.963 315.080 373.405 1.00 41.01  ? 53  SER A O   1 
ATOM 374  C CB  . SER A 1 54  ? 289.315 312.529 371.440 1.00 41.01  ? 53  SER A CB  1 
ATOM 375  O OG  . SER A 1 54  ? 289.972 311.327 371.090 1.00 41.01  ? 53  SER A OG  1 
ATOM 376  N N   . GLN A 1 55  ? 289.698 315.672 371.366 1.00 51.75  ? 54  GLN A N   1 
ATOM 377  C CA  . GLN A 1 55  ? 289.076 316.986 371.310 1.00 51.75  ? 54  GLN A CA  1 
ATOM 378  C C   . GLN A 1 55  ? 287.852 316.946 370.407 1.00 51.75  ? 54  GLN A C   1 
ATOM 379  O O   . GLN A 1 55  ? 287.623 315.960 369.703 1.00 51.75  ? 54  GLN A O   1 
ATOM 380  C CB  . GLN A 1 55  ? 290.096 318.016 370.811 1.00 51.75  ? 54  GLN A CB  1 
ATOM 381  C CG  . GLN A 1 55  ? 291.205 318.325 371.796 1.00 51.75  ? 54  GLN A CG  1 
ATOM 382  C CD  . GLN A 1 55  ? 292.082 319.461 371.321 1.00 51.75  ? 54  GLN A CD  1 
ATOM 383  O OE1 . GLN A 1 55  ? 291.905 319.975 370.217 1.00 51.75  ? 54  GLN A OE1 1 
ATOM 384  N NE2 . GLN A 1 55  ? 293.022 319.877 372.162 1.00 51.75  ? 54  GLN A NE2 1 
ATOM 385  N N   . PRO A 1 56  ? 287.011 317.988 370.419 1.00 58.46  ? 55  PRO A N   1 
ATOM 386  C CA  . PRO A 1 56  ? 285.951 318.066 369.410 1.00 58.46  ? 55  PRO A CA  1 
ATOM 387  C C   . PRO A 1 56  ? 286.495 318.215 367.997 1.00 58.46  ? 55  PRO A C   1 
ATOM 388  O O   . PRO A 1 56  ? 287.645 318.596 367.769 1.00 58.46  ? 55  PRO A O   1 
ATOM 389  C CB  . PRO A 1 56  ? 285.154 319.307 369.825 1.00 58.46  ? 55  PRO A CB  1 
ATOM 390  C CG  . PRO A 1 56  ? 285.345 319.391 371.255 1.00 58.46  ? 55  PRO A CG  1 
ATOM 391  C CD  . PRO A 1 56  ? 286.747 318.939 371.515 1.00 58.46  ? 55  PRO A CD  1 
ATOM 392  N N   . SER A 1 57  ? 285.635 317.900 367.039 1.00 72.41  ? 56  SER A N   1 
ATOM 393  C CA  . SER A 1 57  ? 285.978 317.941 365.628 1.00 72.41  ? 56  SER A CA  1 
ATOM 394  C C   . SER A 1 57  ? 284.710 318.288 364.858 1.00 72.41  ? 56  SER A C   1 
ATOM 395  O O   . SER A 1 57  ? 283.733 318.774 365.437 1.00 72.41  ? 56  SER A O   1 
ATOM 396  C CB  . SER A 1 57  ? 286.594 316.601 365.194 1.00 72.41  ? 56  SER A CB  1 
ATOM 397  O OG  . SER A 1 57  ? 285.641 315.558 365.295 1.00 72.41  ? 56  SER A OG  1 
ATOM 398  N N   . ARG A 1 58  ? 284.721 318.051 363.549 1.00 79.31  ? 57  ARG A N   1 
ATOM 399  C CA  . ARG A 1 58  ? 283.484 318.140 362.791 1.00 79.31  ? 57  ARG A CA  1 
ATOM 400  C C   . ARG A 1 58  ? 282.622 316.898 362.957 1.00 79.31  ? 57  ARG A C   1 
ATOM 401  O O   . ARG A 1 58  ? 281.429 316.940 362.641 1.00 79.31  ? 57  ARG A O   1 
ATOM 402  C CB  . ARG A 1 58  ? 283.776 318.374 361.309 1.00 79.31  ? 57  ARG A CB  1 
ATOM 403  C CG  . ARG A 1 58  ? 284.449 319.704 361.020 1.00 79.31  ? 57  ARG A CG  1 
ATOM 404  C CD  . ARG A 1 58  ? 284.618 319.935 359.526 1.00 79.31  ? 57  ARG A CD  1 
ATOM 405  N NE  . ARG A 1 58  ? 283.330 320.129 358.864 1.00 79.31  ? 57  ARG A NE  1 
ATOM 406  C CZ  . ARG A 1 58  ? 282.796 319.272 357.999 1.00 79.31  ? 57  ARG A CZ  1 
ATOM 407  N NH1 . ARG A 1 58  ? 281.617 319.528 357.452 1.00 79.31  ? 57  ARG A NH1 1 
ATOM 408  N NH2 . ARG A 1 58  ? 283.445 318.162 357.680 1.00 79.31  ? 57  ARG A NH2 1 
ATOM 409  N N   . ASN A 1 59  ? 283.198 315.798 363.442 1.00 77.17  ? 58  ASN A N   1 
ATOM 410  C CA  . ASN A 1 59  ? 282.414 314.596 363.706 1.00 77.17  ? 58  ASN A CA  1 
ATOM 411  C C   . ASN A 1 59  ? 281.726 314.671 365.065 1.00 77.17  ? 58  ASN A C   1 
ATOM 412  O O   . ASN A 1 59  ? 280.494 314.663 365.150 1.00 77.17  ? 58  ASN A O   1 
ATOM 413  C CB  . ASN A 1 59  ? 283.311 313.358 363.625 1.00 77.17  ? 58  ASN A CB  1 
ATOM 414  C CG  . ASN A 1 59  ? 283.726 313.033 362.208 1.00 77.17  ? 58  ASN A CG  1 
ATOM 415  O OD1 . ASN A 1 59  ? 282.913 313.082 361.286 1.00 77.17  ? 58  ASN A OD1 1 
ATOM 416  N ND2 . ASN A 1 59  ? 284.999 312.708 362.024 1.00 77.17  ? 58  ASN A ND2 1 
ATOM 417  N N   . ARG A 1 60  ? 282.508 314.758 366.138 1.00 72.03  ? 59  ARG A N   1 
ATOM 418  C CA  . ARG A 1 60  ? 281.983 314.714 367.494 1.00 72.03  ? 59  ARG A CA  1 
ATOM 419  C C   . ARG A 1 60  ? 282.116 316.076 368.161 1.00 72.03  ? 59  ARG A C   1 
ATOM 420  O O   . ARG A 1 60  ? 283.135 316.757 368.011 1.00 72.03  ? 59  ARG A O   1 
ATOM 421  C CB  . ARG A 1 60  ? 282.702 313.648 368.322 1.00 72.03  ? 59  ARG A CB  1 
ATOM 422  C CG  . ARG A 1 60  ? 282.544 312.241 367.767 1.00 72.03  ? 59  ARG A CG  1 
ATOM 423  C CD  . ARG A 1 60  ? 281.099 311.770 367.855 1.00 72.03  ? 59  ARG A CD  1 
ATOM 424  N NE  . ARG A 1 60  ? 280.937 310.396 367.385 1.00 72.03  ? 59  ARG A NE  1 
ATOM 425  C CZ  . ARG A 1 60  ? 279.765 309.779 367.272 1.00 72.03  ? 59  ARG A CZ  1 
ATOM 426  N NH1 . ARG A 1 60  ? 278.645 310.414 367.588 1.00 72.03  ? 59  ARG A NH1 1 
ATOM 427  N NH2 . ARG A 1 60  ? 279.711 308.527 366.839 1.00 72.03  ? 59  ARG A NH2 1 
ATOM 428  N N   . LYS A 1 61  ? 281.079 316.460 368.901 1.00 62.87  ? 60  LYS A N   1 
ATOM 429  C CA  . LYS A 1 61  ? 280.975 317.781 369.502 1.00 62.87  ? 60  LYS A CA  1 
ATOM 430  C C   . LYS A 1 61  ? 281.450 317.817 370.946 1.00 62.87  ? 60  LYS A C   1 
ATOM 431  O O   . LYS A 1 61  ? 281.266 318.832 371.621 1.00 62.87  ? 60  LYS A O   1 
ATOM 432  C CB  . LYS A 1 61  ? 279.526 318.266 369.434 1.00 62.87  ? 60  LYS A CB  1 
ATOM 433  C CG  . LYS A 1 61  ? 279.007 318.508 368.032 1.00 62.87  ? 60  LYS A CG  1 
ATOM 434  C CD  . LYS A 1 61  ? 277.589 319.040 368.076 1.00 62.87  ? 60  LYS A CD  1 
ATOM 435  C CE  . LYS A 1 61  ? 276.622 317.937 368.466 1.00 62.87  ? 60  LYS A CE  1 
ATOM 436  N NZ  . LYS A 1 61  ? 275.205 318.381 368.412 1.00 62.87  ? 60  LYS A NZ  1 
ATOM 437  N N   . ASN A 1 62  ? 282.054 316.739 371.437 1.00 49.81  ? 61  ASN A N   1 
ATOM 438  C CA  . ASN A 1 62  ? 282.397 316.651 372.845 1.00 49.81  ? 61  ASN A CA  1 
ATOM 439  C C   . ASN A 1 62  ? 283.710 315.904 373.016 1.00 49.81  ? 61  ASN A C   1 
ATOM 440  O O   . ASN A 1 62  ? 284.217 315.272 372.090 1.00 49.81  ? 61  ASN A O   1 
ATOM 441  C CB  . ASN A 1 62  ? 281.268 315.994 373.643 1.00 49.81  ? 61  ASN A CB  1 
ATOM 442  C CG  . ASN A 1 62  ? 280.825 314.671 373.060 1.00 49.81  ? 61  ASN A CG  1 
ATOM 443  O OD1 . ASN A 1 62  ? 281.371 314.191 372.070 1.00 49.81  ? 61  ASN A OD1 1 
ATOM 444  N ND2 . ASN A 1 62  ? 279.817 314.072 373.678 1.00 49.81  ? 61  ASN A ND2 1 
ATOM 445  N N   . TYR A 1 63  ? 284.252 315.987 374.224 1.00 40.88  ? 62  TYR A N   1 
ATOM 446  C CA  . TYR A 1 63  ? 285.525 315.380 374.553 1.00 40.88  ? 62  TYR A CA  1 
ATOM 447  C C   . TYR A 1 63  ? 285.356 313.895 374.828 1.00 40.88  ? 62  TYR A C   1 
ATOM 448  O O   . TYR A 1 63  ? 284.248 313.384 374.984 1.00 40.88  ? 62  TYR A O   1 
ATOM 449  C CB  . TYR A 1 63  ? 286.146 316.081 375.750 1.00 40.88  ? 62  TYR A CB  1 
ATOM 450  C CG  . TYR A 1 63  ? 286.651 317.461 375.435 1.00 40.88  ? 62  TYR A CG  1 
ATOM 451  C CD1 . TYR A 1 63  ? 287.945 317.655 374.989 1.00 40.88  ? 62  TYR A CD1 1 
ATOM 452  C CD2 . TYR A 1 63  ? 285.831 318.564 375.560 1.00 40.88  ? 62  TYR A CD2 1 
ATOM 453  C CE1 . TYR A 1 63  ? 288.417 318.909 374.708 1.00 40.88  ? 62  TYR A CE1 1 
ATOM 454  C CE2 . TYR A 1 63  ? 286.291 319.821 375.268 1.00 40.88  ? 62  TYR A CE2 1 
ATOM 455  C CZ  . TYR A 1 63  ? 287.583 319.987 374.842 1.00 40.88  ? 62  TYR A CZ  1 
ATOM 456  O OH  . TYR A 1 63  ? 288.041 321.246 374.552 1.00 40.88  ? 62  TYR A OH  1 
ATOM 457  N N   . LYS A 1 64  ? 286.486 313.194 374.885 1.00 37.02  ? 63  LYS A N   1 
ATOM 458  C CA  . LYS A 1 64  ? 286.471 311.742 375.032 1.00 37.02  ? 63  LYS A CA  1 
ATOM 459  C C   . LYS A 1 64  ? 287.812 311.319 375.627 1.00 37.02  ? 63  LYS A C   1 
ATOM 460  O O   . LYS A 1 64  ? 288.834 311.380 374.944 1.00 37.02  ? 63  LYS A O   1 
ATOM 461  C CB  . LYS A 1 64  ? 286.223 311.065 373.700 1.00 37.02  ? 63  LYS A CB  1 
ATOM 462  C CG  . LYS A 1 64  ? 286.086 309.573 373.797 1.00 37.02  ? 63  LYS A CG  1 
ATOM 463  C CD  . LYS A 1 64  ? 285.763 308.975 372.450 1.00 37.02  ? 63  LYS A CD  1 
ATOM 464  C CE  . LYS A 1 64  ? 284.366 309.387 372.018 1.00 37.02  ? 63  LYS A CE  1 
ATOM 465  N NZ  . LYS A 1 64  ? 283.317 308.829 372.915 1.00 37.02  ? 63  LYS A NZ  1 
ATOM 466  N N   . VAL A 1 65  ? 287.793 310.899 376.881 1.00 31.88  ? 64  VAL A N   1 
ATOM 467  C CA  . VAL A 1 65  ? 288.946 310.302 377.545 1.00 31.88  ? 64  VAL A CA  1 
ATOM 468  C C   . VAL A 1 65  ? 288.724 308.801 377.549 1.00 31.88  ? 64  VAL A C   1 
ATOM 469  O O   . VAL A 1 65  ? 287.586 308.343 377.679 1.00 31.88  ? 64  VAL A O   1 
ATOM 470  C CB  . VAL A 1 65  ? 289.095 310.861 378.971 1.00 31.88  ? 64  VAL A CB  1 
ATOM 471  C CG1 . VAL A 1 65  ? 290.321 310.307 379.676 1.00 31.88  ? 64  VAL A CG1 1 
ATOM 472  C CG2 . VAL A 1 65  ? 289.135 312.363 378.924 1.00 31.88  ? 64  VAL A CG2 1 
ATOM 473  N N   . GLN A 1 66  ? 289.788 308.027 377.374 1.00 31.66  ? 65  GLN A N   1 
ATOM 474  C CA  . GLN A 1 66  ? 289.628 306.591 377.195 1.00 31.66  ? 65  GLN A CA  1 
ATOM 475  C C   . GLN A 1 66  ? 290.845 305.871 377.743 1.00 31.66  ? 65  GLN A C   1 
ATOM 476  O O   . GLN A 1 66  ? 291.940 306.003 377.195 1.00 31.66  ? 65  GLN A O   1 
ATOM 477  C CB  . GLN A 1 66  ? 289.429 306.270 375.722 1.00 31.66  ? 65  GLN A CB  1 
ATOM 478  C CG  . GLN A 1 66  ? 289.141 304.835 375.422 1.00 31.66  ? 65  GLN A CG  1 
ATOM 479  C CD  . GLN A 1 66  ? 288.891 304.623 373.956 1.00 31.66  ? 65  GLN A CD  1 
ATOM 480  O OE1 . GLN A 1 66  ? 289.025 305.547 373.159 1.00 31.66  ? 65  GLN A OE1 1 
ATOM 481  N NE2 . GLN A 1 66  ? 288.496 303.415 373.590 1.00 31.66  ? 65  GLN A NE2 1 
ATOM 482  N N   . VAL A 1 67  ? 290.654 305.115 378.817 1.00 30.52  ? 66  VAL A N   1 
ATOM 483  C CA  . VAL A 1 67  ? 291.702 304.301 379.417 1.00 30.52  ? 66  VAL A CA  1 
ATOM 484  C C   . VAL A 1 67  ? 291.445 302.872 378.977 1.00 30.52  ? 66  VAL A C   1 
ATOM 485  O O   . VAL A 1 67  ? 290.295 302.480 378.772 1.00 30.52  ? 66  VAL A O   1 
ATOM 486  C CB  . VAL A 1 67  ? 291.683 304.430 380.953 1.00 30.52  ? 66  VAL A CB  1 
ATOM 487  C CG1 . VAL A 1 67  ? 292.885 303.757 381.606 1.00 30.52  ? 66  VAL A CG1 1 
ATOM 488  C CG2 . VAL A 1 67  ? 291.592 305.866 381.337 1.00 30.52  ? 66  VAL A CG2 1 
ATOM 489  N N   . LYS A 1 68  ? 292.506 302.093 378.808 1.00 32.86  ? 67  LYS A N   1 
ATOM 490  C CA  . LYS A 1 68  ? 292.358 300.735 378.300 1.00 32.86  ? 67  LYS A CA  1 
ATOM 491  C C   . LYS A 1 68  ? 293.527 299.910 378.813 1.00 32.86  ? 67  LYS A C   1 
ATOM 492  O O   . LYS A 1 68  ? 294.666 300.152 378.409 1.00 32.86  ? 67  LYS A O   1 
ATOM 493  C CB  . LYS A 1 68  ? 292.313 300.743 376.778 1.00 32.86  ? 67  LYS A CB  1 
ATOM 494  C CG  . LYS A 1 68  ? 292.010 299.405 376.153 1.00 32.86  ? 67  LYS A CG  1 
ATOM 495  C CD  . LYS A 1 68  ? 292.126 299.461 374.640 1.00 32.86  ? 67  LYS A CD  1 
ATOM 496  C CE  . LYS A 1 68  ? 290.789 299.656 373.967 1.00 32.86  ? 67  LYS A CE  1 
ATOM 497  N NZ  . LYS A 1 68  ? 290.358 301.065 374.048 1.00 32.86  ? 67  LYS A NZ  1 
ATOM 498  N N   . ILE A 1 69  ? 293.267 298.948 379.694 1.00 35.05  ? 68  ILE A N   1 
ATOM 499  C CA  . ILE A 1 69  ? 294.328 298.145 380.292 1.00 35.05  ? 68  ILE A CA  1 
ATOM 500  C C   . ILE A 1 69  ? 294.183 296.701 379.834 1.00 35.05  ? 68  ILE A C   1 
ATOM 501  O O   . ILE A 1 69  ? 293.071 296.230 379.577 1.00 35.05  ? 68  ILE A O   1 
ATOM 502  C CB  . ILE A 1 69  ? 294.328 298.248 381.832 1.00 35.05  ? 68  ILE A CB  1 
ATOM 503  C CG1 . ILE A 1 69  ? 293.063 297.670 382.447 1.00 35.05  ? 68  ILE A CG1 1 
ATOM 504  C CG2 . ILE A 1 69  ? 294.399 299.687 382.257 1.00 35.05  ? 68  ILE A CG2 1 
ATOM 505  C CD1 . ILE A 1 69  ? 293.110 297.609 383.947 1.00 35.05  ? 68  ILE A CD1 1 
ATOM 506  N N   . GLN A 1 70  ? 295.315 296.016 379.673 1.00 41.18  ? 69  GLN A N   1 
ATOM 507  C CA  . GLN A 1 70  ? 295.325 294.587 379.400 1.00 41.18  ? 69  GLN A CA  1 
ATOM 508  C C   . GLN A 1 70  ? 296.468 293.958 380.173 1.00 41.18  ? 69  GLN A C   1 
ATOM 509  O O   . GLN A 1 70  ? 297.467 294.613 380.472 1.00 41.18  ? 69  GLN A O   1 
ATOM 510  C CB  . GLN A 1 70  ? 295.470 294.254 377.911 1.00 41.18  ? 69  GLN A CB  1 
ATOM 511  C CG  . GLN A 1 70  ? 296.830 294.499 377.316 1.00 41.18  ? 69  GLN A CG  1 
ATOM 512  C CD  . GLN A 1 70  ? 296.891 294.120 375.860 1.00 41.18  ? 69  GLN A CD  1 
ATOM 513  O OE1 . GLN A 1 70  ? 295.921 293.619 375.303 1.00 41.18  ? 69  GLN A OE1 1 
ATOM 514  N NE2 . GLN A 1 70  ? 298.034 294.352 375.233 1.00 41.18  ? 69  GLN A NE2 1 
ATOM 515  N N   . ASN A 1 71  ? 296.305 292.685 380.506 1.00 43.31  ? 70  ASN A N   1 
ATOM 516  C CA  . ASN A 1 71  ? 297.316 291.968 381.268 1.00 43.31  ? 70  ASN A CA  1 
ATOM 517  C C   . ASN A 1 71  ? 297.255 290.462 381.040 1.00 43.31  ? 70  ASN A C   1 
ATOM 518  O O   . ASN A 1 71  ? 296.283 289.804 381.424 1.00 43.31  ? 70  ASN A O   1 
ATOM 519  C CB  . ASN A 1 71  ? 297.205 292.332 382.748 1.00 43.31  ? 70  ASN A CB  1 
ATOM 520  C CG  . ASN A 1 71  ? 295.801 292.386 383.228 1.00 43.31  ? 70  ASN A CG  1 
ATOM 521  O OD1 . ASN A 1 71  ? 294.876 292.033 382.509 1.00 43.31  ? 70  ASN A OD1 1 
ATOM 522  N ND2 . ASN A 1 71  ? 295.619 292.876 384.443 1.00 43.31  ? 70  ASN A ND2 1 
ATOM 523  N N   . PRO A 1 72  ? 298.296 289.882 380.430 1.00 48.33  ? 71  PRO A N   1 
ATOM 524  C CA  . PRO A 1 72  ? 298.241 288.475 380.021 1.00 48.33  ? 71  PRO A CA  1 
ATOM 525  C C   . PRO A 1 72  ? 298.561 287.496 381.136 1.00 48.33  ? 71  PRO A C   1 
ATOM 526  O O   . PRO A 1 72  ? 298.817 287.896 382.274 1.00 48.33  ? 71  PRO A O   1 
ATOM 527  C CB  . PRO A 1 72  ? 299.310 288.404 378.930 1.00 48.33  ? 71  PRO A CB  1 
ATOM 528  C CG  . PRO A 1 72  ? 300.296 289.397 379.350 1.00 48.33  ? 71  PRO A CG  1 
ATOM 529  C CD  . PRO A 1 72  ? 299.538 290.524 379.978 1.00 48.33  ? 71  PRO A CD  1 
ATOM 530  N N   . THR A 1 73  ? 298.567 286.207 380.803 1.00 53.75  ? 72  THR A N   1 
ATOM 531  C CA  . THR A 1 73  ? 298.968 285.150 381.719 1.00 53.75  ? 72  THR A CA  1 
ATOM 532  C C   . THR A 1 73  ? 299.963 284.236 381.021 1.00 53.75  ? 72  THR A C   1 
ATOM 533  O O   . THR A 1 73  ? 299.688 283.737 379.927 1.00 53.75  ? 72  THR A O   1 
ATOM 534  C CB  . THR A 1 73  ? 297.760 284.354 382.201 1.00 53.75  ? 72  THR A CB  1 
ATOM 535  O OG1 . THR A 1 73  ? 296.846 285.241 382.850 1.00 53.75  ? 72  THR A OG1 1 
ATOM 536  C CG2 . THR A 1 73  ? 298.189 283.298 383.189 1.00 53.75  ? 72  THR A CG2 1 
ATOM 537  N N   . ALA A 1 74  ? 301.112 284.020 381.652 1.00 62.81  ? 73  ALA A N   1 
ATOM 538  C CA  . ALA A 1 74  ? 302.220 283.291 381.054 1.00 62.81  ? 73  ALA A CA  1 
ATOM 539  C C   . ALA A 1 74  ? 302.207 281.841 381.514 1.00 62.81  ? 73  ALA A C   1 
ATOM 540  O O   . ALA A 1 74  ? 302.149 281.568 382.716 1.00 62.81  ? 73  ALA A O   1 
ATOM 541  C CB  . ALA A 1 74  ? 303.551 283.944 381.421 1.00 62.81  ? 73  ALA A CB  1 
ATOM 542  N N   . CYS A 1 75  ? 302.274 280.918 380.558 1.00 73.70  ? 74  CYS A N   1 
ATOM 543  C CA  . CYS A 1 75  ? 302.298 279.487 380.839 1.00 73.70  ? 74  CYS A CA  1 
ATOM 544  C C   . CYS A 1 75  ? 303.576 278.899 380.263 1.00 73.70  ? 74  CYS A C   1 
ATOM 545  O O   . CYS A 1 75  ? 303.672 278.678 379.051 1.00 73.70  ? 74  CYS A O   1 
ATOM 546  C CB  . CYS A 1 75  ? 301.074 278.790 380.253 1.00 73.70  ? 74  CYS A CB  1 
ATOM 547  S SG  . CYS A 1 75  ? 300.992 277.024 380.624 1.00 73.70  ? 74  CYS A SG  1 
ATOM 548  N N   . THR A 1 76  ? 304.549 278.636 381.129 1.00 80.32  ? 75  THR A N   1 
ATOM 549  C CA  . THR A 1 76  ? 305.824 278.062 380.708 1.00 80.32  ? 75  THR A CA  1 
ATOM 550  C C   . THR A 1 76  ? 305.607 276.581 380.431 1.00 80.32  ? 75  THR A C   1 
ATOM 551  O O   . THR A 1 76  ? 305.616 275.754 381.347 1.00 80.32  ? 75  THR A O   1 
ATOM 552  C CB  . THR A 1 76  ? 306.887 278.275 381.780 1.00 80.32  ? 75  THR A CB  1 
ATOM 553  O OG1 . THR A 1 76  ? 306.981 279.669 382.087 1.00 80.32  ? 75  THR A OG1 1 
ATOM 554  C CG2 . THR A 1 76  ? 308.239 277.794 381.283 1.00 80.32  ? 75  THR A CG2 1 
ATOM 555  N N   . ALA A 1 77  ? 305.393 276.241 379.164 1.00 88.04  ? 76  ALA A N   1 
ATOM 556  C CA  . ALA A 1 77  ? 305.156 274.857 378.790 1.00 88.04  ? 76  ALA A CA  1 
ATOM 557  C C   . ALA A 1 77  ? 306.458 274.065 378.818 1.00 88.04  ? 76  ALA A C   1 
ATOM 558  O O   . ALA A 1 77  ? 307.559 274.620 378.782 1.00 88.04  ? 76  ALA A O   1 
ATOM 559  C CB  . ALA A 1 77  ? 304.524 274.772 377.402 1.00 88.04  ? 76  ALA A CB  1 
ATOM 560  N N   . ASN A 1 78  ? 306.318 272.745 378.884 1.00 93.90  ? 77  ASN A N   1 
ATOM 561  C CA  . ASN A 1 78  ? 307.483 271.873 378.877 1.00 93.90  ? 77  ASN A CA  1 
ATOM 562  C C   . ASN A 1 78  ? 308.065 271.778 377.474 1.00 93.90  ? 77  ASN A C   1 
ATOM 563  O O   . ASN A 1 78  ? 307.334 271.707 376.483 1.00 93.90  ? 77  ASN A O   1 
ATOM 564  C CB  . ASN A 1 78  ? 307.107 270.484 379.390 1.00 93.90  ? 77  ASN A CB  1 
ATOM 565  C CG  . ASN A 1 78  ? 306.813 270.472 380.876 1.00 93.90  ? 77  ASN A CG  1 
ATOM 566  O OD1 . ASN A 1 78  ? 307.514 271.110 381.660 1.00 93.90  ? 77  ASN A OD1 1 
ATOM 567  N ND2 . ASN A 1 78  ? 305.774 269.746 381.270 1.00 93.90  ? 77  ASN A ND2 1 
ATOM 568  N N   . GLY A 1 79  ? 309.392 271.777 377.394 1.00 90.99  ? 78  GLY A N   1 
ATOM 569  C CA  . GLY A 1 79  ? 310.055 271.728 376.107 1.00 90.99  ? 78  GLY A CA  1 
ATOM 570  C C   . GLY A 1 79  ? 310.158 273.056 375.400 1.00 90.99  ? 78  GLY A C   1 
ATOM 571  O O   . GLY A 1 79  ? 310.258 273.085 374.169 1.00 90.99  ? 78  GLY A O   1 
ATOM 572  N N   . SER A 1 80  ? 310.131 274.162 376.139 1.00 88.68  ? 79  SER A N   1 
ATOM 573  C CA  . SER A 1 80  ? 310.234 275.487 375.547 1.00 88.68  ? 79  SER A CA  1 
ATOM 574  C C   . SER A 1 80  ? 310.821 276.427 376.584 1.00 88.68  ? 79  SER A C   1 
ATOM 575  O O   . SER A 1 80  ? 310.450 276.365 377.758 1.00 88.68  ? 79  SER A O   1 
ATOM 576  C CB  . SER A 1 80  ? 308.868 275.990 375.073 1.00 88.68  ? 79  SER A CB  1 
ATOM 577  O OG  . SER A 1 80  ? 308.976 277.281 374.506 1.00 88.68  ? 79  SER A OG  1 
ATOM 578  N N   . CYS A 1 81  ? 311.740 277.287 376.150 1.00 84.41  ? 80  CYS A N   1 
ATOM 579  C CA  . CYS A 1 81  ? 312.410 278.187 377.079 1.00 84.41  ? 80  CYS A CA  1 
ATOM 580  C C   . CYS A 1 81  ? 311.597 279.445 377.345 1.00 84.41  ? 80  CYS A C   1 
ATOM 581  O O   . CYS A 1 81  ? 311.627 279.974 378.460 1.00 84.41  ? 80  CYS A O   1 
ATOM 582  C CB  . CYS A 1 81  ? 313.791 278.555 376.536 1.00 84.41  ? 80  CYS A CB  1 
ATOM 583  S SG  . CYS A 1 81  ? 314.791 279.594 377.625 1.00 84.41  ? 80  CYS A SG  1 
ATOM 584  N N   . ASP A 1 82  ? 310.865 279.928 376.346 1.00 79.67  ? 81  ASP A N   1 
ATOM 585  C CA  . ASP A 1 82  ? 310.111 281.165 376.437 1.00 79.67  ? 81  ASP A CA  1 
ATOM 586  C C   . ASP A 1 82  ? 308.638 280.895 376.703 1.00 79.67  ? 81  ASP A C   1 
ATOM 587  O O   . ASP A 1 82  ? 308.055 279.992 376.088 1.00 79.67  ? 81  ASP A O   1 
ATOM 588  C CB  . ASP A 1 82  ? 310.283 281.980 375.153 1.00 79.67  ? 81  ASP A CB  1 
ATOM 589  C CG  . ASP A 1 82  ? 310.097 281.148 373.900 1.00 79.67  ? 81  ASP A CG  1 
ATOM 590  O OD1 . ASP A 1 82  ? 309.973 279.913 374.005 1.00 79.67  ? 81  ASP A OD1 1 
ATOM 591  O OD2 . ASP A 1 82  ? 310.086 281.730 372.799 1.00 79.67  ? 81  ASP A OD2 1 
ATOM 592  N N   . PRO A 1 83  ? 308.015 281.622 377.628 1.00 70.18  ? 82  PRO A N   1 
ATOM 593  C CA  . PRO A 1 83  ? 306.598 281.394 377.919 1.00 70.18  ? 82  PRO A CA  1 
ATOM 594  C C   . PRO A 1 83  ? 305.701 281.848 376.782 1.00 70.18  ? 82  PRO A C   1 
ATOM 595  O O   . PRO A 1 83  ? 306.048 282.715 375.979 1.00 70.18  ? 82  PRO A O   1 
ATOM 596  C CB  . PRO A 1 83  ? 306.355 282.244 379.169 1.00 70.18  ? 82  PRO A CB  1 
ATOM 597  C CG  . PRO A 1 83  ? 307.686 282.417 379.775 1.00 70.18  ? 82  PRO A CG  1 
ATOM 598  C CD  . PRO A 1 83  ? 308.634 282.505 378.628 1.00 70.18  ? 82  PRO A CD  1 
ATOM 599  N N   . SER A 1 84  ? 304.526 281.240 376.724 1.00 64.84  ? 83  SER A N   1 
ATOM 600  C CA  . SER A 1 84  ? 303.464 281.673 375.835 1.00 64.84  ? 83  SER A CA  1 
ATOM 601  C C   . SER A 1 84  ? 302.377 282.357 376.646 1.00 64.84  ? 83  SER A C   1 
ATOM 602  O O   . SER A 1 84  ? 302.289 282.197 377.865 1.00 64.84  ? 83  SER A O   1 
ATOM 603  C CB  . SER A 1 84  ? 302.870 280.493 375.062 1.00 64.84  ? 83  SER A CB  1 
ATOM 604  O OG  . SER A 1 84  ? 303.821 279.920 374.186 1.00 64.84  ? 83  SER A OG  1 
ATOM 605  N N   . VAL A 1 85  ? 301.550 283.133 375.963 1.00 56.39  ? 84  VAL A N   1 
ATOM 606  C CA  . VAL A 1 85  ? 300.358 283.696 376.577 1.00 56.39  ? 84  VAL A CA  1 
ATOM 607  C C   . VAL A 1 85  ? 299.221 282.701 376.414 1.00 56.39  ? 84  VAL A C   1 
ATOM 608  O O   . VAL A 1 85  ? 299.120 282.008 375.396 1.00 56.39  ? 84  VAL A O   1 
ATOM 609  C CB  . VAL A 1 85  ? 300.008 285.068 375.977 1.00 56.39  ? 84  VAL A CB  1 
ATOM 610  C CG1 . VAL A 1 85  ? 301.058 286.079 376.351 1.00 56.39  ? 84  VAL A CG1 1 
ATOM 611  C CG2 . VAL A 1 85  ? 299.903 284.997 374.465 1.00 56.39  ? 84  VAL A CG2 1 
ATOM 612  N N   . THR A 1 86  ? 298.395 282.589 377.446 1.00 54.12  ? 85  THR A N   1 
ATOM 613  C CA  . THR A 1 86  ? 297.244 281.704 377.402 1.00 54.12  ? 85  THR A CA  1 
ATOM 614  C C   . THR A 1 86  ? 295.962 282.484 377.156 1.00 54.12  ? 85  THR A C   1 
ATOM 615  O O   . THR A 1 86  ? 295.117 282.061 376.361 1.00 54.12  ? 85  THR A O   1 
ATOM 616  C CB  . THR A 1 86  ? 297.153 280.915 378.710 1.00 54.12  ? 85  THR A CB  1 
ATOM 617  O OG1 . THR A 1 86  ? 298.382 280.220 378.926 1.00 54.12  ? 85  THR A OG1 1 
ATOM 618  C CG2 . THR A 1 86  ? 296.045 279.894 378.642 1.00 54.12  ? 85  THR A CG2 1 
ATOM 619  N N   . ARG A 1 87  ? 295.836 283.646 377.785 1.00 47.65  ? 86  ARG A N   1 
ATOM 620  C CA  . ARG A 1 87  ? 294.603 284.410 377.779 1.00 47.65  ? 86  ARG A CA  1 
ATOM 621  C C   . ARG A 1 87  ? 294.910 285.840 378.189 1.00 47.65  ? 86  ARG A C   1 
ATOM 622  O O   . ARG A 1 87  ? 295.878 286.100 378.905 1.00 47.65  ? 86  ARG A O   1 
ATOM 623  C CB  . ARG A 1 87  ? 293.580 283.778 378.723 1.00 47.65  ? 86  ARG A CB  1 
ATOM 624  C CG  . ARG A 1 87  ? 294.070 283.661 380.149 1.00 47.65  ? 86  ARG A CG  1 
ATOM 625  C CD  . ARG A 1 87  ? 293.065 282.942 381.014 1.00 47.65  ? 86  ARG A CD  1 
ATOM 626  N NE  . ARG A 1 87  ? 293.502 282.861 382.399 1.00 47.65  ? 86  ARG A NE  1 
ATOM 627  C CZ  . ARG A 1 87  ? 294.199 281.851 382.901 1.00 47.65  ? 86  ARG A CZ  1 
ATOM 628  N NH1 . ARG A 1 87  ? 294.517 280.824 382.134 1.00 47.65  ? 86  ARG A NH1 1 
ATOM 629  N NH2 . ARG A 1 87  ? 294.550 281.859 384.175 1.00 47.65  ? 86  ARG A NH2 1 
ATOM 630  N N   . GLN A 1 88  ? 294.086 286.765 377.714 1.00 43.50  ? 87  GLN A N   1 
ATOM 631  C CA  . GLN A 1 88  ? 294.148 288.160 378.108 1.00 43.50  ? 87  GLN A CA  1 
ATOM 632  C C   . GLN A 1 88  ? 292.969 288.473 379.023 1.00 43.50  ? 87  GLN A C   1 
ATOM 633  O O   . GLN A 1 88  ? 291.990 287.729 379.080 1.00 43.50  ? 87  GLN A O   1 
ATOM 634  C CB  . GLN A 1 88  ? 294.086 289.082 376.885 1.00 43.50  ? 87  GLN A CB  1 
ATOM 635  C CG  . GLN A 1 88  ? 295.118 288.856 375.791 1.00 43.50  ? 87  GLN A CG  1 
ATOM 636  C CD  . GLN A 1 88  ? 296.528 289.180 376.196 1.00 43.50  ? 87  GLN A CD  1 
ATOM 637  O OE1 . GLN A 1 88  ? 297.364 288.294 376.314 1.00 43.50  ? 87  GLN A OE1 1 
ATOM 638  N NE2 . GLN A 1 88  ? 296.812 290.459 376.384 1.00 43.50  ? 87  GLN A NE2 1 
ATOM 639  N N   . ALA A 1 89  ? 293.065 289.590 379.735 1.00 38.94  ? 88  ALA A N   1 
ATOM 640  C CA  . ALA A 1 89  ? 291.936 290.168 380.452 1.00 38.94  ? 88  ALA A CA  1 
ATOM 641  C C   . ALA A 1 89  ? 291.920 291.663 380.194 1.00 38.94  ? 88  ALA A C   1 
ATOM 642  O O   . ALA A 1 89  ? 292.956 292.321 380.289 1.00 38.94  ? 88  ALA A O   1 
ATOM 643  C CB  . ALA A 1 89  ? 292.016 289.904 381.950 1.00 38.94  ? 88  ALA A CB  1 
ATOM 644  N N   . TYR A 1 90  ? 290.750 292.201 379.873 1.00 37.07  ? 89  TYR A N   1 
ATOM 645  C CA  . TYR A 1 90  ? 290.650 293.560 379.375 1.00 37.07  ? 89  TYR A CA  1 
ATOM 646  C C   . TYR A 1 90  ? 289.763 294.405 380.273 1.00 37.07  ? 89  TYR A C   1 
ATOM 647  O O   . TYR A 1 90  ? 288.899 293.894 380.985 1.00 37.07  ? 89  TYR A O   1 
ATOM 648  C CB  . TYR A 1 90  ? 290.088 293.583 377.959 1.00 37.07  ? 89  TYR A CB  1 
ATOM 649  C CG  . TYR A 1 90  ? 290.930 292.879 376.934 1.00 37.07  ? 89  TYR A CG  1 
ATOM 650  C CD1 . TYR A 1 90  ? 292.059 293.476 376.409 1.00 37.07  ? 89  TYR A CD1 1 
ATOM 651  C CD2 . TYR A 1 90  ? 290.573 291.629 376.464 1.00 37.07  ? 89  TYR A CD2 1 
ATOM 652  C CE1 . TYR A 1 90  ? 292.823 292.839 375.464 1.00 37.07  ? 89  TYR A CE1 1 
ATOM 653  C CE2 . TYR A 1 90  ? 291.328 290.985 375.520 1.00 37.07  ? 89  TYR A CE2 1 
ATOM 654  C CZ  . TYR A 1 90  ? 292.449 291.594 375.021 1.00 37.07  ? 89  TYR A CZ  1 
ATOM 655  O OH  . TYR A 1 90  ? 293.201 290.947 374.075 1.00 37.07  ? 89  TYR A OH  1 
ATOM 656  N N   . ALA A 1 91  ? 289.989 295.715 380.221 1.00 31.97  ? 90  ALA A N   1 
ATOM 657  C CA  . ALA A 1 91  ? 289.090 296.695 380.825 1.00 31.97  ? 90  ALA A CA  1 
ATOM 658  C C   . ALA A 1 91  ? 289.316 298.014 380.118 1.00 31.97  ? 90  ALA A C   1 
ATOM 659  O O   . ALA A 1 91  ? 290.406 298.578 380.225 1.00 31.97  ? 90  ALA A O   1 
ATOM 660  C CB  . ALA A 1 91  ? 289.340 296.846 382.317 1.00 31.97  ? 90  ALA A CB  1 
ATOM 661  N N   . ASP A 1 92  ? 288.315 298.505 379.397 1.00 32.19  ? 91  ASP A N   1 
ATOM 662  C CA  . ASP A 1 92  ? 288.447 299.767 378.675 1.00 32.19  ? 91  ASP A CA  1 
ATOM 663  C C   . ASP A 1 92  ? 287.375 300.755 379.105 1.00 32.19  ? 91  ASP A C   1 
ATOM 664  O O   . ASP A 1 92  ? 286.211 300.636 378.716 1.00 32.19  ? 91  ASP A O   1 
ATOM 665  C CB  . ASP A 1 92  ? 288.433 299.550 377.162 1.00 32.19  ? 91  ASP A CB  1 
ATOM 666  C CG  . ASP A 1 92  ? 287.354 298.609 376.714 1.00 32.19  ? 91  ASP A CG  1 
ATOM 667  O OD1 . ASP A 1 92  ? 286.724 297.986 377.587 1.00 32.19  ? 91  ASP A OD1 1 
ATOM 668  O OD2 . ASP A 1 92  ? 287.128 298.499 375.491 1.00 32.19  ? 91  ASP A OD2 1 
ATOM 669  N N   . VAL A 1 93  ? 287.775 301.732 379.897 1.00 29.84  ? 92  VAL A N   1 
ATOM 670  C CA  . VAL A 1 93  ? 286.897 302.816 380.312 1.00 29.84  ? 92  VAL A CA  1 
ATOM 671  C C   . VAL A 1 93  ? 286.841 303.852 379.202 1.00 29.84  ? 92  VAL A C   1 
ATOM 672  O O   . VAL A 1 93  ? 287.826 304.073 378.496 1.00 29.84  ? 92  VAL A O   1 
ATOM 673  C CB  . VAL A 1 93  ? 287.431 303.423 381.621 1.00 29.84  ? 92  VAL A CB  1 
ATOM 674  C CG1 . VAL A 1 93  ? 286.449 304.389 382.224 1.00 29.84  ? 92  VAL A CG1 1 
ATOM 675  C CG2 . VAL A 1 93  ? 287.747 302.336 382.576 1.00 29.84  ? 92  VAL A CG2 1 
ATOM 676  N N   . THR A 1 94  ? 285.686 304.487 379.025 1.00 28.93  ? 93  THR A N   1 
ATOM 677  C CA  . THR A 1 94  ? 285.590 305.644 378.148 1.00 28.93  ? 93  THR A CA  1 
ATOM 678  C C   . THR A 1 94  ? 284.649 306.670 378.761 1.00 28.93  ? 93  THR A C   1 
ATOM 679  O O   . THR A 1 94  ? 283.507 306.357 379.101 1.00 28.93  ? 93  THR A O   1 
ATOM 680  C CB  . THR A 1 94  ? 285.167 305.236 376.727 1.00 28.93  ? 93  THR A CB  1 
ATOM 681  O OG1 . THR A 1 94  ? 284.947 306.402 375.928 1.00 28.93  ? 93  THR A OG1 1 
ATOM 682  C CG2 . THR A 1 94  ? 283.958 304.310 376.691 1.00 28.93  ? 93  THR A CG2 1 
ATOM 683  N N   . PHE A 1 95  ? 285.150 307.886 378.940 1.00 29.73  ? 94  PHE A N   1 
ATOM 684  C CA  . PHE A 1 95  ? 284.391 308.995 379.493 1.00 29.73  ? 94  PHE A CA  1 
ATOM 685  C C   . PHE A 1 95  ? 283.933 309.905 378.366 1.00 29.73  ? 94  PHE A C   1 
ATOM 686  O O   . PHE A 1 95  ? 284.528 309.927 377.290 1.00 29.73  ? 94  PHE A O   1 
ATOM 687  C CB  . PHE A 1 95  ? 285.238 309.806 380.468 1.00 29.73  ? 94  PHE A CB  1 
ATOM 688  C CG  . PHE A 1 95  ? 285.666 309.056 381.690 1.00 29.73  ? 94  PHE A CG  1 
ATOM 689  C CD1 . PHE A 1 95  ? 284.846 308.974 382.793 1.00 29.73  ? 94  PHE A CD1 1 
ATOM 690  C CD2 . PHE A 1 95  ? 286.907 308.464 381.746 1.00 29.73  ? 94  PHE A CD2 1 
ATOM 691  C CE1 . PHE A 1 95  ? 285.245 308.304 383.925 1.00 29.73  ? 94  PHE A CE1 1 
ATOM 692  C CE2 . PHE A 1 95  ? 287.314 307.788 382.873 1.00 29.73  ? 94  PHE A CE2 1 
ATOM 693  C CZ  . PHE A 1 95  ? 286.478 307.705 383.963 1.00 29.73  ? 94  PHE A CZ  1 
ATOM 694  N N   . SER A 1 96  ? 282.880 310.672 378.615 1.00 32.16  ? 95  SER A N   1 
ATOM 695  C CA  . SER A 1 96  ? 282.381 311.595 377.604 1.00 32.16  ? 95  SER A CA  1 
ATOM 696  C C   . SER A 1 96  ? 281.899 312.860 378.286 1.00 32.16  ? 95  SER A C   1 
ATOM 697  O O   . SER A 1 96  ? 280.943 312.818 379.059 1.00 32.16  ? 95  SER A O   1 
ATOM 698  C CB  . SER A 1 96  ? 281.254 310.967 376.792 1.00 32.16  ? 95  SER A CB  1 
ATOM 699  O OG  . SER A 1 96  ? 280.799 311.868 375.806 1.00 32.16  ? 95  SER A OG  1 
ATOM 700  N N   . PHE A 1 97  ? 282.549 313.979 377.997 1.00 34.43  ? 96  PHE A N   1 
ATOM 701  C CA  . PHE A 1 97  ? 282.211 315.252 378.609 1.00 34.43  ? 96  PHE A CA  1 
ATOM 702  C C   . PHE A 1 97  ? 282.045 316.290 377.512 1.00 34.43  ? 96  PHE A C   1 
ATOM 703  O O   . PHE A 1 97  ? 282.840 316.333 376.574 1.00 34.43  ? 96  PHE A O   1 
ATOM 704  C CB  . PHE A 1 97  ? 283.289 315.693 379.585 1.00 34.43  ? 96  PHE A CB  1 
ATOM 705  C CG  . PHE A 1 97  ? 283.580 314.693 380.654 1.00 34.43  ? 96  PHE A CG  1 
ATOM 706  C CD1 . PHE A 1 97  ? 282.656 314.432 381.647 1.00 34.43  ? 96  PHE A CD1 1 
ATOM 707  C CD2 . PHE A 1 97  ? 284.800 314.051 380.695 1.00 34.43  ? 96  PHE A CD2 1 
ATOM 708  C CE1 . PHE A 1 97  ? 282.926 313.522 382.643 1.00 34.43  ? 96  PHE A CE1 1 
ATOM 709  C CE2 . PHE A 1 97  ? 285.079 313.143 381.690 1.00 34.43  ? 96  PHE A CE2 1 
ATOM 710  C CZ  . PHE A 1 97  ? 284.136 312.878 382.666 1.00 34.43  ? 96  PHE A CZ  1 
ATOM 711  N N   . THR A 1 98  ? 281.013 317.123 377.620 1.00 36.55  ? 97  THR A N   1 
ATOM 712  C CA  . THR A 1 98  ? 280.814 318.157 376.617 1.00 36.55  ? 97  THR A CA  1 
ATOM 713  C C   . THR A 1 98  ? 281.719 319.348 376.904 1.00 36.55  ? 97  THR A C   1 
ATOM 714  O O   . THR A 1 98  ? 282.440 319.397 377.902 1.00 36.55  ? 97  THR A O   1 
ATOM 715  C CB  . THR A 1 98  ? 279.357 318.602 376.555 1.00 36.55  ? 97  THR A CB  1 
ATOM 716  O OG1 . THR A 1 98  ? 278.984 319.201 377.798 1.00 36.55  ? 97  THR A OG1 1 
ATOM 717  C CG2 . THR A 1 98  ? 278.451 317.429 376.278 1.00 36.55  ? 97  THR A CG2 1 
ATOM 718  N N   . GLN A 1 99  ? 281.664 320.335 376.018 1.00 37.11  ? 98  GLN A N   1 
ATOM 719  C CA  . GLN A 1 99  ? 282.590 321.452 376.061 1.00 37.11  ? 98  GLN A CA  1 
ATOM 720  C C   . GLN A 1 99  ? 282.248 322.487 377.119 1.00 37.11  ? 98  GLN A C   1 
ATOM 721  O O   . GLN A 1 99  ? 283.083 323.346 377.407 1.00 37.11  ? 98  GLN A O   1 
ATOM 722  C CB  . GLN A 1 99  ? 282.648 322.121 374.693 1.00 37.11  ? 98  GLN A CB  1 
ATOM 723  C CG  . GLN A 1 99  ? 281.328 322.673 374.226 1.00 37.11  ? 98  GLN A CG  1 
ATOM 724  C CD  . GLN A 1 99  ? 281.429 323.316 372.868 1.00 37.11  ? 98  GLN A CD  1 
ATOM 725  O OE1 . GLN A 1 99  ? 282.515 323.431 372.305 1.00 37.11  ? 98  GLN A OE1 1 
ATOM 726  N NE2 . GLN A 1 99  ? 280.295 323.732 372.326 1.00 37.11  ? 98  GLN A NE2 1 
ATOM 727  N N   . TYR A 1 100 ? 281.055 322.444 377.699 1.00 36.68  ? 99  TYR A N   1 
ATOM 728  C CA  . TYR A 1 100 ? 280.695 323.378 378.753 1.00 36.68  ? 99  TYR A CA  1 
ATOM 729  C C   . TYR A 1 100 ? 280.719 322.744 380.130 1.00 36.68  ? 99  TYR A C   1 
ATOM 730  O O   . TYR A 1 100 ? 280.293 323.380 381.096 1.00 36.68  ? 99  TYR A O   1 
ATOM 731  C CB  . TYR A 1 100 ? 279.317 323.979 378.499 1.00 36.68  ? 99  TYR A CB  1 
ATOM 732  C CG  . TYR A 1 100 ? 279.257 324.913 377.321 1.00 36.68  ? 99  TYR A CG  1 
ATOM 733  C CD1 . TYR A 1 100 ? 279.800 326.188 377.395 1.00 36.68  ? 99  TYR A CD1 1 
ATOM 734  C CD2 . TYR A 1 100 ? 278.623 324.538 376.149 1.00 36.68  ? 99  TYR A CD2 1 
ATOM 735  C CE1 . TYR A 1 100 ? 279.742 327.049 376.321 1.00 36.68  ? 99  TYR A CE1 1 
ATOM 736  C CE2 . TYR A 1 100 ? 278.557 325.392 375.073 1.00 36.68  ? 99  TYR A CE2 1 
ATOM 737  C CZ  . TYR A 1 100 ? 279.115 326.643 375.165 1.00 36.68  ? 99  TYR A CZ  1 
ATOM 738  O OH  . TYR A 1 100 ? 279.043 327.490 374.091 1.00 36.68  ? 99  TYR A OH  1 
ATOM 739  N N   . SER A 1 101 ? 281.185 321.507 380.241 1.00 36.02  ? 100 SER A N   1 
ATOM 740  C CA  . SER A 1 101 ? 281.248 320.851 381.536 1.00 36.02  ? 100 SER A CA  1 
ATOM 741  C C   . SER A 1 101 ? 282.376 321.436 382.366 1.00 36.02  ? 100 SER A C   1 
ATOM 742  O O   . SER A 1 101 ? 283.461 321.711 381.856 1.00 36.02  ? 100 SER A O   1 
ATOM 743  C CB  . SER A 1 101 ? 281.453 319.355 381.361 1.00 36.02  ? 100 SER A CB  1 
ATOM 744  O OG  . SER A 1 101 ? 282.708 319.114 380.764 1.00 36.02  ? 100 SER A OG  1 
ATOM 745  N N   . THR A 1 102 ? 282.113 321.630 383.651 1.00 38.06  ? 101 THR A N   1 
ATOM 746  C CA  . THR A 1 102 ? 283.077 322.268 384.523 1.00 38.06  ? 101 THR A CA  1 
ATOM 747  C C   . THR A 1 102 ? 284.066 321.245 385.064 1.00 38.06  ? 101 THR A C   1 
ATOM 748  O O   . THR A 1 102 ? 284.091 320.083 384.661 1.00 38.06  ? 101 THR A O   1 
ATOM 749  C CB  . THR A 1 102 ? 282.375 322.981 385.670 1.00 38.06  ? 101 THR A CB  1 
ATOM 750  O OG1 . THR A 1 102 ? 281.730 322.015 386.501 1.00 38.06  ? 101 THR A OG1 1 
ATOM 751  C CG2 . THR A 1 102 ? 281.329 323.929 385.142 1.00 38.06  ? 101 THR A CG2 1 
ATOM 752  N N   . ASP A 1 103 ? 284.899 321.695 385.995 1.00 41.34  ? 102 ASP A N   1 
ATOM 753  C CA  . ASP A 1 103 ? 285.941 320.846 386.553 1.00 41.34  ? 102 ASP A CA  1 
ATOM 754  C C   . ASP A 1 103 ? 285.381 319.909 387.615 1.00 41.34  ? 102 ASP A C   1 
ATOM 755  O O   . ASP A 1 103 ? 285.822 318.763 387.729 1.00 41.34  ? 102 ASP A O   1 
ATOM 756  C CB  . ASP A 1 103 ? 287.042 321.725 387.137 1.00 41.34  ? 102 ASP A CB  1 
ATOM 757  C CG  . ASP A 1 103 ? 288.321 320.974 387.396 1.00 41.34  ? 102 ASP A CG  1 
ATOM 758  O OD1 . ASP A 1 103 ? 288.405 319.781 387.052 1.00 41.34  ? 102 ASP A OD1 1 
ATOM 759  O OD2 . ASP A 1 103 ? 289.252 321.583 387.961 1.00 41.34  ? 102 ASP A OD2 1 
ATOM 760  N N   . GLU A 1 104 ? 284.421 320.378 388.404 1.00 42.40  ? 103 GLU A N   1 
ATOM 761  C CA  . GLU A 1 104 ? 283.867 319.555 389.465 1.00 42.40  ? 103 GLU A CA  1 
ATOM 762  C C   . GLU A 1 104 ? 282.785 318.608 388.979 1.00 42.40  ? 103 GLU A C   1 
ATOM 763  O O   . GLU A 1 104 ? 282.353 317.748 389.750 1.00 42.40  ? 103 GLU A O   1 
ATOM 764  C CB  . GLU A 1 104 ? 283.321 320.438 390.581 1.00 42.40  ? 103 GLU A CB  1 
ATOM 765  C CG  . GLU A 1 104 ? 284.403 321.144 391.357 1.00 42.40  ? 103 GLU A CG  1 
ATOM 766  C CD  . GLU A 1 104 ? 283.855 321.981 392.488 1.00 42.40  ? 103 GLU A CD  1 
ATOM 767  O OE1 . GLU A 1 104 ? 282.620 322.142 392.568 1.00 42.40  ? 103 GLU A OE1 1 
ATOM 768  O OE2 . GLU A 1 104 ? 284.660 322.466 393.308 1.00 42.40  ? 103 GLU A OE2 1 
ATOM 769  N N   . GLU A 1 105 ? 282.335 318.741 387.736 1.00 39.81  ? 104 GLU A N   1 
ATOM 770  C CA  . GLU A 1 105 ? 281.449 317.737 387.167 1.00 39.81  ? 104 GLU A CA  1 
ATOM 771  C C   . GLU A 1 105 ? 282.243 316.567 386.619 1.00 39.81  ? 104 GLU A C   1 
ATOM 772  O O   . GLU A 1 105 ? 281.811 315.417 386.721 1.00 39.81  ? 104 GLU A O   1 
ATOM 773  C CB  . GLU A 1 105 ? 280.597 318.343 386.061 1.00 39.81  ? 104 GLU A CB  1 
ATOM 774  C CG  . GLU A 1 105 ? 279.679 319.437 386.529 1.00 39.81  ? 104 GLU A CG  1 
ATOM 775  C CD  . GLU A 1 105 ? 278.888 320.035 385.393 1.00 39.81  ? 104 GLU A CD  1 
ATOM 776  O OE1 . GLU A 1 105 ? 279.088 319.605 384.240 1.00 39.81  ? 104 GLU A OE1 1 
ATOM 777  O OE2 . GLU A 1 105 ? 278.086 320.954 385.644 1.00 39.81  ? 104 GLU A OE2 1 
ATOM 778  N N   . ARG A 1 106 ? 283.401 316.845 386.026 1.00 35.89  ? 105 ARG A N   1 
ATOM 779  C CA  . ARG A 1 106 ? 284.248 315.787 385.499 1.00 35.89  ? 105 ARG A CA  1 
ATOM 780  C C   . ARG A 1 106 ? 284.968 315.033 386.601 1.00 35.89  ? 105 ARG A C   1 
ATOM 781  O O   . ARG A 1 106 ? 285.184 313.827 386.477 1.00 35.89  ? 105 ARG A O   1 
ATOM 782  C CB  . ARG A 1 106 ? 285.264 316.375 384.532 1.00 35.89  ? 105 ARG A CB  1 
ATOM 783  C CG  . ARG A 1 106 ? 284.647 316.971 383.309 1.00 35.89  ? 105 ARG A CG  1 
ATOM 784  C CD  . ARG A 1 106 ? 285.692 317.246 382.280 1.00 35.89  ? 105 ARG A CD  1 
ATOM 785  N NE  . ARG A 1 106 ? 286.673 318.218 382.733 1.00 35.89  ? 105 ARG A NE  1 
ATOM 786  C CZ  . ARG A 1 106 ? 286.589 319.521 382.510 1.00 35.89  ? 105 ARG A CZ  1 
ATOM 787  N NH1 . ARG A 1 106 ? 285.575 320.008 381.819 1.00 35.89  ? 105 ARG A NH1 1 
ATOM 788  N NH2 . ARG A 1 106 ? 287.532 320.336 382.952 1.00 35.89  ? 105 ARG A NH2 1 
ATOM 789  N N   . ALA A 1 107 ? 285.345 315.713 387.674 1.00 35.67  ? 106 ALA A N   1 
ATOM 790  C CA  . ALA A 1 107 ? 285.968 315.041 388.802 1.00 35.67  ? 106 ALA A CA  1 
ATOM 791  C C   . ALA A 1 107 ? 284.970 314.253 389.625 1.00 35.67  ? 106 ALA A C   1 
ATOM 792  O O   . ALA A 1 107 ? 285.372 313.369 390.382 1.00 35.67  ? 106 ALA A O   1 
ATOM 793  C CB  . ALA A 1 107 ? 286.673 316.051 389.698 1.00 35.67  ? 106 ALA A CB  1 
ATOM 794  N N   . PHE A 1 108 ? 283.683 314.575 389.517 1.00 36.33  ? 107 PHE A N   1 
ATOM 795  C CA  . PHE A 1 108 ? 282.674 313.810 390.232 1.00 36.33  ? 107 PHE A CA  1 
ATOM 796  C C   . PHE A 1 108 ? 282.497 312.445 389.593 1.00 36.33  ? 107 PHE A C   1 
ATOM 797  O O   . PHE A 1 108 ? 282.277 311.454 390.291 1.00 36.33  ? 107 PHE A O   1 
ATOM 798  C CB  . PHE A 1 108 ? 281.353 314.575 390.248 1.00 36.33  ? 107 PHE A CB  1 
ATOM 799  C CG  . PHE A 1 108 ? 280.320 313.985 391.153 1.00 36.33  ? 107 PHE A CG  1 
ATOM 800  C CD1 . PHE A 1 108 ? 280.351 314.243 392.508 1.00 36.33  ? 107 PHE A CD1 1 
ATOM 801  C CD2 . PHE A 1 108 ? 279.325 313.166 390.657 1.00 36.33  ? 107 PHE A CD2 1 
ATOM 802  C CE1 . PHE A 1 108 ? 279.409 313.710 393.348 1.00 36.33  ? 107 PHE A CE1 1 
ATOM 803  C CE2 . PHE A 1 108 ? 278.382 312.628 391.495 1.00 36.33  ? 107 PHE A CE2 1 
ATOM 804  C CZ  . PHE A 1 108 ? 278.426 312.898 392.841 1.00 36.33  ? 107 PHE A CZ  1 
ATOM 805  N N   . VAL A 1 109 ? 282.615 312.371 388.267 1.00 33.88  ? 108 VAL A N   1 
ATOM 806  C CA  . VAL A 1 109 ? 282.487 311.102 387.559 1.00 33.88  ? 108 VAL A CA  1 
ATOM 807  C C   . VAL A 1 109 ? 283.685 310.202 387.841 1.00 33.88  ? 108 VAL A C   1 
ATOM 808  O O   . VAL A 1 109 ? 283.532 308.994 388.053 1.00 33.88  ? 108 VAL A O   1 
ATOM 809  C CB  . VAL A 1 109 ? 282.318 311.367 386.053 1.00 33.88  ? 108 VAL A CB  1 
ATOM 810  C CG1 . VAL A 1 109 ? 282.290 310.079 385.271 1.00 33.88  ? 108 VAL A CG1 1 
ATOM 811  C CG2 . VAL A 1 109 ? 281.051 312.131 385.801 1.00 33.88  ? 108 VAL A CG2 1 
ATOM 812  N N   . ARG A 1 110 ? 284.889 310.777 387.852 1.00 33.50  ? 109 ARG A N   1 
ATOM 813  C CA  . ARG A 1 110 ? 286.107 310.006 388.082 1.00 33.50  ? 109 ARG A CA  1 
ATOM 814  C C   . ARG A 1 110 ? 286.140 309.421 389.483 1.00 33.50  ? 109 ARG A C   1 
ATOM 815  O O   . ARG A 1 110 ? 286.544 308.272 389.676 1.00 33.50  ? 109 ARG A O   1 
ATOM 816  C CB  . ARG A 1 110 ? 287.329 310.890 387.864 1.00 33.50  ? 109 ARG A CB  1 
ATOM 817  C CG  . ARG A 1 110 ? 288.640 310.203 388.126 1.00 33.50  ? 109 ARG A CG  1 
ATOM 818  C CD  . ARG A 1 110 ? 289.795 311.167 388.039 1.00 33.50  ? 109 ARG A CD  1 
ATOM 819  N NE  . ARG A 1 110 ? 289.666 312.277 388.976 1.00 33.50  ? 109 ARG A NE  1 
ATOM 820  C CZ  . ARG A 1 110 ? 289.964 312.222 390.269 1.00 33.50  ? 109 ARG A CZ  1 
ATOM 821  N NH1 . ARG A 1 110 ? 290.393 311.101 390.817 1.00 33.50  ? 109 ARG A NH1 1 
ATOM 822  N NH2 . ARG A 1 110 ? 289.818 313.298 391.021 1.00 33.50  ? 109 ARG A NH2 1 
ATOM 823  N N   . THR A 1 111 ? 285.675 310.177 390.465 1.00 35.41  ? 110 THR A N   1 
ATOM 824  C CA  . THR A 1 111 ? 285.761 309.725 391.842 1.00 35.41  ? 110 THR A CA  1 
ATOM 825  C C   . THR A 1 111 ? 284.591 308.830 392.223 1.00 35.41  ? 110 THR A C   1 
ATOM 826  O O   . THR A 1 111 ? 284.735 307.982 393.112 1.00 35.41  ? 110 THR A O   1 
ATOM 827  C CB  . THR A 1 111 ? 285.827 310.933 392.768 1.00 35.41  ? 110 THR A CB  1 
ATOM 828  O OG1 . THR A 1 111 ? 286.666 311.916 392.168 1.00 35.41  ? 110 THR A OG1 1 
ATOM 829  C CG2 . THR A 1 111 ? 286.489 310.542 394.053 1.00 35.41  ? 110 THR A CG2 1 
ATOM 830  N N   . GLU A 1 112 ? 283.435 308.997 391.573 1.00 35.14  ? 111 GLU A N   1 
ATOM 831  C CA  . GLU A 1 112 ? 282.329 308.062 391.755 1.00 35.14  ? 111 GLU A CA  1 
ATOM 832  C C   . GLU A 1 112 ? 282.692 306.680 391.244 1.00 35.14  ? 111 GLU A C   1 
ATOM 833  O O   . GLU A 1 112 ? 282.421 305.680 391.909 1.00 35.14  ? 111 GLU A O   1 
ATOM 834  C CB  . GLU A 1 112 ? 281.079 308.564 391.034 1.00 35.14  ? 111 GLU A CB  1 
ATOM 835  C CG  . GLU A 1 112 ? 279.876 307.656 391.170 1.00 35.14  ? 111 GLU A CG  1 
ATOM 836  C CD  . GLU A 1 112 ? 278.649 308.197 390.470 1.00 35.14  ? 111 GLU A CD  1 
ATOM 837  O OE1 . GLU A 1 112 ? 278.745 309.269 389.843 1.00 35.14  ? 111 GLU A OE1 1 
ATOM 838  O OE2 . GLU A 1 112 ? 277.587 307.549 390.541 1.00 35.14  ? 111 GLU A OE2 1 
ATOM 839  N N   . LEU A 1 113 ? 283.327 306.611 390.075 1.00 32.05  ? 112 LEU A N   1 
ATOM 840  C CA  . LEU A 1 113 ? 283.741 305.332 389.511 1.00 32.05  ? 112 LEU A CA  1 
ATOM 841  C C   . LEU A 1 113 ? 284.854 304.689 390.324 1.00 32.05  ? 112 LEU A C   1 
ATOM 842  O O   . LEU A 1 113 ? 284.886 303.466 390.455 1.00 32.05  ? 112 LEU A O   1 
ATOM 843  C CB  . LEU A 1 113 ? 284.180 305.533 388.066 1.00 32.05  ? 112 LEU A CB  1 
ATOM 844  C CG  . LEU A 1 113 ? 284.615 304.325 387.250 1.00 32.05  ? 112 LEU A CG  1 
ATOM 845  C CD1 . LEU A 1 113 ? 283.453 303.406 387.056 1.00 32.05  ? 112 LEU A CD1 1 
ATOM 846  C CD2 . LEU A 1 113 ? 285.162 304.768 385.921 1.00 32.05  ? 112 LEU A CD2 1 
ATOM 847  N N   . ALA A 1 114 ? 285.758 305.482 390.893 1.00 33.40  ? 113 ALA A N   1 
ATOM 848  C CA  . ALA A 1 114 ? 286.802 304.902 391.729 1.00 33.40  ? 113 ALA A CA  1 
ATOM 849  C C   . ALA A 1 114 ? 286.246 304.384 393.046 1.00 33.40  ? 113 ALA A C   1 
ATOM 850  O O   . ALA A 1 114 ? 286.770 303.412 393.595 1.00 33.40  ? 113 ALA A O   1 
ATOM 851  C CB  . ALA A 1 114 ? 287.900 305.928 391.987 1.00 33.40  ? 113 ALA A CB  1 
ATOM 852  N N   . ALA A 1 115 ? 285.190 305.003 393.560 1.00 32.99  ? 114 ALA A N   1 
ATOM 853  C CA  . ALA A 1 115 ? 284.564 304.543 394.788 1.00 32.99  ? 114 ALA A CA  1 
ATOM 854  C C   . ALA A 1 115 ? 283.551 303.440 394.556 1.00 32.99  ? 114 ALA A C   1 
ATOM 855  O O   . ALA A 1 115 ? 283.200 302.731 395.501 1.00 32.99  ? 114 ALA A O   1 
ATOM 856  C CB  . ALA A 1 115 ? 283.879 305.704 395.509 1.00 32.99  ? 114 ALA A CB  1 
ATOM 857  N N   . LEU A 1 116 ? 283.074 303.279 393.325 1.00 33.76  ? 115 LEU A N   1 
ATOM 858  C CA  . LEU A 1 116 ? 282.066 302.269 393.035 1.00 33.76  ? 115 LEU A CA  1 
ATOM 859  C C   . LEU A 1 116 ? 282.680 300.898 392.821 1.00 33.76  ? 115 LEU A C   1 
ATOM 860  O O   . LEU A 1 116 ? 282.049 299.889 393.146 1.00 33.76  ? 115 LEU A O   1 
ATOM 861  C CB  . LEU A 1 116 ? 281.277 302.672 391.794 1.00 33.76  ? 115 LEU A CB  1 
ATOM 862  C CG  . LEU A 1 116 ? 280.031 301.944 391.322 1.00 33.76  ? 115 LEU A CG  1 
ATOM 863  C CD1 . LEU A 1 116 ? 278.886 302.170 392.266 1.00 33.76  ? 115 LEU A CD1 1 
ATOM 864  C CD2 . LEU A 1 116 ? 279.683 302.414 389.940 1.00 33.76  ? 115 LEU A CD2 1 
ATOM 865  N N   . LEU A 1 117 ? 283.903 300.837 392.287 1.00 33.77  ? 116 LEU A N   1 
ATOM 866  C CA  . LEU A 1 117 ? 284.600 299.575 392.059 1.00 33.77  ? 116 LEU A CA  1 
ATOM 867  C C   . LEU A 1 117 ? 284.983 298.854 393.346 1.00 33.77  ? 116 LEU A C   1 
ATOM 868  O O   . LEU A 1 117 ? 285.367 297.686 393.280 1.00 33.77  ? 116 LEU A O   1 
ATOM 869  C CB  . LEU A 1 117 ? 285.862 299.797 391.219 1.00 33.77  ? 116 LEU A CB  1 
ATOM 870  C CG  . LEU A 1 117 ? 285.866 299.689 389.688 1.00 33.77  ? 116 LEU A CG  1 
ATOM 871  C CD1 . LEU A 1 117 ? 285.569 298.292 389.276 1.00 33.77  ? 116 LEU A CD1 1 
ATOM 872  C CD2 . LEU A 1 117 ? 284.873 300.577 389.036 1.00 33.77  ? 116 LEU A CD2 1 
ATOM 873  N N   . ALA A 1 118 ? 284.898 299.504 394.502 1.00 34.70  ? 117 ALA A N   1 
ATOM 874  C CA  . ALA A 1 118 ? 285.143 298.855 395.781 1.00 34.70  ? 117 ALA A CA  1 
ATOM 875  C C   . ALA A 1 118 ? 283.863 298.533 396.542 1.00 34.70  ? 117 ALA A C   1 
ATOM 876  O O   . ALA A 1 118 ? 283.920 298.294 397.750 1.00 34.70  ? 117 ALA A O   1 
ATOM 877  C CB  . ALA A 1 118 ? 286.049 299.728 396.643 1.00 34.70  ? 117 ALA A CB  1 
ATOM 878  N N   . SER A 1 119 ? 282.732 298.530 395.885 1.00 37.54  ? 118 SER A N   1 
ATOM 879  C CA  . SER A 1 119 ? 281.451 298.282 396.527 1.00 37.54  ? 118 SER A CA  1 
ATOM 880  C C   . SER A 1 119 ? 281.052 296.825 396.344 1.00 37.54  ? 118 SER A C   1 
ATOM 881  O O   . SER A 1 119 ? 281.428 296.203 395.351 1.00 37.54  ? 118 SER A O   1 
ATOM 882  C CB  . SER A 1 119 ? 280.374 299.178 395.931 1.00 37.54  ? 118 SER A CB  1 
ATOM 883  O OG  . SER A 1 119 ? 280.060 298.772 394.615 1.00 37.54  ? 118 SER A OG  1 
ATOM 884  N N   . PRO A 1 120 ? 280.272 296.251 397.272 1.00 40.81  ? 119 PRO A N   1 
ATOM 885  C CA  . PRO A 1 120 ? 279.894 294.834 397.145 1.00 40.81  ? 119 PRO A CA  1 
ATOM 886  C C   . PRO A 1 120 ? 278.963 294.531 395.984 1.00 40.81  ? 119 PRO A C   1 
ATOM 887  O O   . PRO A 1 120 ? 278.728 293.353 395.700 1.00 40.81  ? 119 PRO A O   1 
ATOM 888  C CB  . PRO A 1 120 ? 279.212 294.537 398.481 1.00 40.81  ? 119 PRO A CB  1 
ATOM 889  C CG  . PRO A 1 120 ? 279.744 295.551 399.401 1.00 40.81  ? 119 PRO A CG  1 
ATOM 890  C CD  . PRO A 1 120 ? 279.914 296.779 398.596 1.00 40.81  ? 119 PRO A CD  1 
ATOM 891  N N   . LEU A 1 121 ? 278.422 295.545 395.314 1.00 39.57  ? 120 LEU A N   1 
ATOM 892  C CA  . LEU A 1 121 ? 277.725 295.303 394.061 1.00 39.57  ? 120 LEU A CA  1 
ATOM 893  C C   . LEU A 1 121 ? 278.704 294.928 392.963 1.00 39.57  ? 120 LEU A C   1 
ATOM 894  O O   . LEU A 1 121 ? 278.439 294.017 392.174 1.00 39.57  ? 120 LEU A O   1 
ATOM 895  C CB  . LEU A 1 121 ? 276.938 296.539 393.651 1.00 39.57  ? 120 LEU A CB  1 
ATOM 896  C CG  . LEU A 1 121 ? 276.013 296.331 392.462 1.00 39.57  ? 120 LEU A CG  1 
ATOM 897  C CD1 . LEU A 1 121 ? 274.870 295.443 392.884 1.00 39.57  ? 120 LEU A CD1 1 
ATOM 898  C CD2 . LEU A 1 121 ? 275.518 297.653 391.944 1.00 39.57  ? 120 LEU A CD2 1 
ATOM 899  N N   . LEU A 1 122 ? 279.842 295.621 392.892 1.00 36.47  ? 121 LEU A N   1 
ATOM 900  C CA  . LEU A 1 122 ? 280.794 295.440 391.807 1.00 36.47  ? 121 LEU A CA  1 
ATOM 901  C C   . LEU A 1 122 ? 281.988 294.576 392.170 1.00 36.47  ? 121 LEU A C   1 
ATOM 902  O O   . LEU A 1 122 ? 282.720 294.172 391.267 1.00 36.47  ? 121 LEU A O   1 
ATOM 903  C CB  . LEU A 1 122 ? 281.303 296.786 391.292 1.00 36.47  ? 121 LEU A CB  1 
ATOM 904  C CG  . LEU A 1 122 ? 280.466 297.509 390.245 1.00 36.47  ? 121 LEU A CG  1 
ATOM 905  C CD1 . LEU A 1 122 ? 279.270 298.210 390.842 1.00 36.47  ? 121 LEU A CD1 1 
ATOM 906  C CD2 . LEU A 1 122 ? 281.336 298.486 389.512 1.00 36.47  ? 121 LEU A CD2 1 
ATOM 907  N N   . ILE A 1 123 ? 282.233 294.316 393.454 1.00 39.57  ? 122 ILE A N   1 
ATOM 908  C CA  . ILE A 1 123 ? 283.114 293.211 393.813 1.00 39.57  ? 122 ILE A CA  1 
ATOM 909  C C   . ILE A 1 123 ? 282.527 291.913 393.293 1.00 39.57  ? 122 ILE A C   1 
ATOM 910  O O   . ILE A 1 123 ? 283.110 291.246 392.437 1.00 39.57  ? 122 ILE A O   1 
ATOM 911  C CB  . ILE A 1 123 ? 283.330 293.150 395.333 1.00 39.57  ? 122 ILE A CB  1 
ATOM 912  C CG1 . ILE A 1 123 ? 284.082 294.374 395.826 1.00 39.57  ? 122 ILE A CG1 1 
ATOM 913  C CG2 . ILE A 1 123 ? 284.076 291.903 395.708 1.00 39.57  ? 122 ILE A CG2 1 
ATOM 914  C CD1 . ILE A 1 123 ? 284.079 294.500 397.310 1.00 39.57  ? 122 ILE A CD1 1 
ATOM 915  N N   . ASP A 1 124 ? 281.312 291.596 393.734 1.00 41.46  ? 123 ASP A N   1 
ATOM 916  C CA  . ASP A 1 124 ? 280.668 290.331 393.418 1.00 41.46  ? 123 ASP A CA  1 
ATOM 917  C C   . ASP A 1 124 ? 280.295 290.209 391.947 1.00 41.46  ? 123 ASP A C   1 
ATOM 918  O O   . ASP A 1 124 ? 280.138 289.090 391.453 1.00 41.46  ? 123 ASP A O   1 
ATOM 919  C CB  . ASP A 1 124 ? 279.434 290.178 394.302 1.00 41.46  ? 123 ASP A CB  1 
ATOM 920  C CG  . ASP A 1 124 ? 278.819 288.805 394.216 1.00 41.46  ? 123 ASP A CG  1 
ATOM 921  O OD1 . ASP A 1 124 ? 279.397 287.858 394.778 1.00 41.46  ? 123 ASP A OD1 1 
ATOM 922  O OD2 . ASP A 1 124 ? 277.758 288.673 393.584 1.00 41.46  ? 123 ASP A OD2 1 
ATOM 923  N N   . ALA A 1 125 ? 280.169 291.321 391.230 1.00 37.24  ? 124 ALA A N   1 
ATOM 924  C CA  . ALA A 1 125 ? 279.894 291.235 389.802 1.00 37.24  ? 124 ALA A CA  1 
ATOM 925  C C   . ALA A 1 125 ? 281.151 290.927 389.005 1.00 37.24  ? 124 ALA A C   1 
ATOM 926  O O   . ALA A 1 125 ? 281.074 290.293 387.951 1.00 37.24  ? 124 ALA A O   1 
ATOM 927  C CB  . ALA A 1 125 ? 279.263 292.530 389.306 1.00 37.24  ? 124 ALA A CB  1 
ATOM 928  N N   . ILE A 1 126 ? 282.314 291.367 389.476 1.00 36.86  ? 125 ILE A N   1 
ATOM 929  C CA  . ILE A 1 126 ? 283.515 291.268 388.655 1.00 36.86  ? 125 ILE A CA  1 
ATOM 930  C C   . ILE A 1 126 ? 284.343 290.036 388.993 1.00 36.86  ? 125 ILE A C   1 
ATOM 931  O O   . ILE A 1 126 ? 284.570 289.195 388.119 1.00 36.86  ? 125 ILE A O   1 
ATOM 932  C CB  . ILE A 1 126 ? 284.358 292.545 388.748 1.00 36.86  ? 125 ILE A CB  1 
ATOM 933  C CG1 . ILE A 1 126 ? 283.596 293.682 388.093 1.00 36.86  ? 125 ILE A CG1 1 
ATOM 934  C CG2 . ILE A 1 126 ? 285.654 292.367 388.025 1.00 36.86  ? 125 ILE A CG2 1 
ATOM 935  C CD1 . ILE A 1 126 ? 284.170 295.013 388.328 1.00 36.86  ? 125 ILE A CD1 1 
ATOM 936  N N   . ASP A 1 127 ? 284.807 289.897 390.234 1.00 39.37  ? 126 ASP A N   1 
ATOM 937  C CA  . ASP A 1 127 ? 285.685 288.765 390.487 1.00 39.37  ? 126 ASP A CA  1 
ATOM 938  C C   . ASP A 1 127 ? 284.939 287.460 390.739 1.00 39.37  ? 126 ASP A C   1 
ATOM 939  O O   . ASP A 1 127 ? 285.569 286.402 390.771 1.00 39.37  ? 126 ASP A O   1 
ATOM 940  C CB  . ASP A 1 127 ? 286.675 289.077 391.628 1.00 39.37  ? 126 ASP A CB  1 
ATOM 941  C CG  . ASP A 1 127 ? 286.029 289.278 392.985 1.00 39.37  ? 126 ASP A CG  1 
ATOM 942  O OD1 . ASP A 1 127 ? 284.806 289.178 393.145 1.00 39.37  ? 126 ASP A OD1 1 
ATOM 943  O OD2 . ASP A 1 127 ? 286.783 289.555 393.937 1.00 39.37  ? 126 ASP A OD2 1 
ATOM 944  N N   . GLN A 1 128 ? 283.619 287.506 390.901 1.00 38.89  ? 127 GLN A N   1 
ATOM 945  C CA  . GLN A 1 128 ? 282.818 286.310 391.110 1.00 38.89  ? 127 GLN A CA  1 
ATOM 946  C C   . GLN A 1 128 ? 281.876 286.005 389.959 1.00 38.89  ? 127 GLN A C   1 
ATOM 947  O O   . GLN A 1 128 ? 281.345 284.892 389.905 1.00 38.89  ? 127 GLN A O   1 
ATOM 948  C CB  . GLN A 1 128 ? 281.997 286.439 392.397 1.00 38.89  ? 127 GLN A CB  1 
ATOM 949  C CG  . GLN A 1 128 ? 282.799 286.449 393.670 1.00 38.89  ? 127 GLN A CG  1 
ATOM 950  C CD  . GLN A 1 128 ? 283.504 285.140 393.910 1.00 38.89  ? 127 GLN A CD  1 
ATOM 951  O OE1 . GLN A 1 128 ? 284.727 285.058 393.845 1.00 38.89  ? 127 GLN A OE1 1 
ATOM 952  N NE2 . GLN A 1 128 ? 282.732 284.101 394.185 1.00 38.89  ? 127 GLN A NE2 1 
ATOM 953  N N   . LEU A 1 129 ? 281.641 286.972 389.069 1.00 36.06  ? 128 LEU A N   1 
ATOM 954  C CA  . LEU A 1 129 ? 280.782 286.857 387.886 1.00 36.06  ? 128 LEU A CA  1 
ATOM 955  C C   . LEU A 1 129 ? 279.333 286.526 388.233 1.00 36.06  ? 128 LEU A C   1 
ATOM 956  O O   . LEU A 1 129 ? 278.627 285.903 387.443 1.00 36.06  ? 128 LEU A O   1 
ATOM 957  C CB  . LEU A 1 129 ? 281.334 285.849 386.877 1.00 36.06  ? 128 LEU A CB  1 
ATOM 958  C CG  . LEU A 1 129 ? 282.659 286.262 386.255 1.00 36.06  ? 128 LEU A CG  1 
ATOM 959  C CD1 . LEU A 1 129 ? 283.201 285.151 385.393 1.00 36.06  ? 128 LEU A CD1 1 
ATOM 960  C CD2 . LEU A 1 129 ? 282.492 287.515 385.442 1.00 36.06  ? 128 LEU A CD2 1 
ATOM 961  N N   . ASN A 1 130 ? 278.864 286.962 389.397 1.00 38.22  ? 129 ASN A N   1 
ATOM 962  C CA  . ASN A 1 130 ? 277.447 286.805 389.698 1.00 38.22  ? 129 ASN A CA  1 
ATOM 963  C C   . ASN A 1 130 ? 276.703 288.076 389.325 1.00 38.22  ? 129 ASN A C   1 
ATOM 964  O O   . ASN A 1 130 ? 277.177 289.170 389.639 1.00 38.22  ? 129 ASN A O   1 
ATOM 965  C CB  . ASN A 1 130 ? 277.223 286.521 391.173 1.00 38.22  ? 129 ASN A CB  1 
ATOM 966  C CG  . ASN A 1 130 ? 277.880 285.247 391.633 1.00 38.22  ? 129 ASN A CG  1 
ATOM 967  O OD1 . ASN A 1 130 ? 278.757 285.265 392.488 1.00 38.22  ? 129 ASN A OD1 1 
ATOM 968  N ND2 . ASN A 1 130 ? 277.455 284.131 391.071 1.00 38.22  ? 129 ASN A ND2 1 
ATOM 969  N N   . PRO A 1 131 ? 275.556 287.990 388.662 1.00 38.61  ? 130 PRO A N   1 
ATOM 970  C CA  . PRO A 1 131 ? 274.769 289.196 388.408 1.00 38.61  ? 130 PRO A CA  1 
ATOM 971  C C   . PRO A 1 131 ? 274.102 289.699 389.674 1.00 38.61  ? 130 PRO A C   1 
ATOM 972  O O   . PRO A 1 131 ? 274.065 289.030 390.707 1.00 38.61  ? 130 PRO A O   1 
ATOM 973  C CB  . PRO A 1 131 ? 273.735 288.735 387.382 1.00 38.61  ? 130 PRO A CB  1 
ATOM 974  C CG  . PRO A 1 131 ? 274.338 287.546 386.762 1.00 38.61  ? 130 PRO A CG  1 
ATOM 975  C CD  . PRO A 1 131 ? 275.074 286.862 387.860 1.00 38.61  ? 130 PRO A CD  1 
ATOM 976  N N   . ALA A 1 132 ? 273.569 290.910 389.581 1.00 40.61  ? 131 ALA A N   1 
ATOM 977  C CA  . ALA A 1 132 ? 272.900 291.546 390.704 1.00 40.61  ? 131 ALA A CA  1 
ATOM 978  C C   . ALA A 1 132 ? 271.415 291.222 390.654 1.00 40.61  ? 131 ALA A C   1 
ATOM 979  O O   . ALA A 1 132 ? 270.743 291.540 389.670 1.00 40.61  ? 131 ALA A O   1 
ATOM 980  C CB  . ALA A 1 132 ? 273.118 293.054 390.668 1.00 40.61  ? 131 ALA A CB  1 
ATOM 981  N N   . TYR A 1 133 ? 270.908 290.583 391.702 1.00 42.94  ? 132 TYR A N   1 
ATOM 982  C CA  . TYR A 1 133 ? 269.478 290.326 391.808 1.00 42.94  ? 132 TYR A CA  1 
ATOM 983  C C   . TYR A 1 133 ? 268.896 291.137 392.957 1.00 42.94  ? 132 TYR A C   1 
ATOM 984  O O   . TYR A 1 133 ? 267.764 291.607 392.886 1.00 42.94  ? 132 TYR A O   1 
ATOM 985  C CB  . TYR A 1 133 ? 269.198 288.830 391.993 1.00 42.94  ? 132 TYR A CB  1 
ATOM 986  C CG  . TYR A 1 133 ? 269.704 288.236 393.288 1.00 42.94  ? 132 TYR A CG  1 
ATOM 987  C CD1 . TYR A 1 133 ? 271.001 287.775 393.394 1.00 42.94  ? 132 TYR A CD1 1 
ATOM 988  C CD2 . TYR A 1 133 ? 268.872 288.102 394.390 1.00 42.94  ? 132 TYR A CD2 1 
ATOM 989  C CE1 . TYR A 1 133 ? 271.470 287.238 394.568 1.00 42.94  ? 132 TYR A CE1 1 
ATOM 990  C CE2 . TYR A 1 133 ? 269.332 287.570 395.566 1.00 42.94  ? 132 TYR A CE2 1 
ATOM 991  C CZ  . TYR A 1 133 ? 270.630 287.133 395.648 1.00 42.94  ? 132 TYR A CZ  1 
ATOM 992  O OH  . TYR A 1 133 ? 271.089 286.588 396.819 1.00 42.94  ? 132 TYR A OH  1 
ATOM 993  N N   . ALA B 1 2   ? 275.681 290.276 393.487 1.00 44.28  ? 1   ALA B N   1 
ATOM 994  C CA  . ALA B 1 2   ? 275.143 290.311 394.837 1.00 44.28  ? 1   ALA B CA  1 
ATOM 995  C C   . ALA B 1 2   ? 273.658 290.618 394.814 1.00 44.28  ? 1   ALA B C   1 
ATOM 996  O O   . ALA B 1 2   ? 272.959 290.246 393.886 1.00 44.28  ? 1   ALA B O   1 
ATOM 997  C CB  . ALA B 1 2   ? 275.882 291.331 395.670 1.00 44.28  ? 1   ALA B CB  1 
ATOM 998  N N   . LYS B 1 3   ? 273.186 291.315 395.840 1.00 46.38  ? 2   LYS B N   1 
ATOM 999  C CA  . LYS B 1 3   ? 271.789 291.696 395.961 1.00 46.38  ? 2   LYS B CA  1 
ATOM 1000 C C   . LYS B 1 3   ? 271.689 293.214 395.981 1.00 46.38  ? 2   LYS B C   1 
ATOM 1001 O O   . LYS B 1 3   ? 272.513 293.883 396.611 1.00 46.38  ? 2   LYS B O   1 
ATOM 1002 C CB  . LYS B 1 3   ? 271.183 291.099 397.228 1.00 46.38  ? 2   LYS B CB  1 
ATOM 1003 C CG  . LYS B 1 3   ? 269.692 291.252 397.348 1.00 46.38  ? 2   LYS B CG  1 
ATOM 1004 C CD  . LYS B 1 3   ? 269.187 290.514 398.568 1.00 46.38  ? 2   LYS B CD  1 
ATOM 1005 C CE  . LYS B 1 3   ? 267.688 290.653 398.708 1.00 46.38  ? 2   LYS B CE  1 
ATOM 1006 N NZ  . LYS B 1 3   ? 267.190 289.956 399.923 1.00 46.38  ? 2   LYS B NZ  1 
ATOM 1007 N N   . LEU B 1 4   ? 270.692 293.758 395.280 1.00 45.71  ? 3   LEU B N   1 
ATOM 1008 C CA  . LEU B 1 4   ? 270.539 295.206 395.170 1.00 45.71  ? 3   LEU B CA  1 
ATOM 1009 C C   . LEU B 1 4   ? 270.122 295.801 396.507 1.00 45.71  ? 3   LEU B C   1 
ATOM 1010 O O   . LEU B 1 4   ? 269.030 295.525 397.011 1.00 45.71  ? 3   LEU B O   1 
ATOM 1011 C CB  . LEU B 1 4   ? 269.527 295.568 394.090 1.00 45.71  ? 3   LEU B CB  1 
ATOM 1012 C CG  . LEU B 1 4   ? 269.936 295.441 392.629 1.00 45.71  ? 3   LEU B CG  1 
ATOM 1013 C CD1 . LEU B 1 4   ? 268.739 295.684 391.765 1.00 45.71  ? 3   LEU B CD1 1 
ATOM 1014 C CD2 . LEU B 1 4   ? 271.008 296.438 392.295 1.00 45.71  ? 3   LEU B CD2 1 
ATOM 1015 N N   . GLU B 1 5   ? 270.998 296.620 397.076 1.00 50.71  ? 4   GLU B N   1 
ATOM 1016 C CA  . GLU B 1 5   ? 270.687 297.471 398.208 1.00 50.71  ? 4   GLU B CA  1 
ATOM 1017 C C   . GLU B 1 5   ? 271.353 298.815 397.952 1.00 50.71  ? 4   GLU B C   1 
ATOM 1018 O O   . GLU B 1 5   ? 271.976 299.022 396.909 1.00 50.71  ? 4   GLU B O   1 
ATOM 1019 C CB  . GLU B 1 5   ? 271.135 296.824 399.517 1.00 50.71  ? 4   GLU B CB  1 
ATOM 1020 C CG  . GLU B 1 5   ? 272.625 296.586 399.609 1.00 50.71  ? 4   GLU B CG  1 
ATOM 1021 C CD  . GLU B 1 5   ? 273.016 295.848 400.872 1.00 50.71  ? 4   GLU B CD  1 
ATOM 1022 O OE1 . GLU B 1 5   ? 272.113 295.499 401.658 1.00 50.71  ? 4   GLU B OE1 1 
ATOM 1023 O OE2 . GLU B 1 5   ? 274.224 295.621 401.080 1.00 50.71  ? 4   GLU B OE2 1 
ATOM 1024 N N   . THR B 1 6   ? 271.213 299.738 398.899 1.00 49.76  ? 5   THR B N   1 
ATOM 1025 C CA  . THR B 1 6   ? 271.710 301.096 398.710 1.00 49.76  ? 5   THR B CA  1 
ATOM 1026 C C   . THR B 1 6   ? 273.231 301.116 398.750 1.00 49.76  ? 5   THR B C   1 
ATOM 1027 O O   . THR B 1 6   ? 273.836 300.689 399.735 1.00 49.76  ? 5   THR B O   1 
ATOM 1028 C CB  . THR B 1 6   ? 271.153 302.024 399.784 1.00 49.76  ? 5   THR B CB  1 
ATOM 1029 O OG1 . THR B 1 6   ? 271.628 301.596 401.062 1.00 49.76  ? 5   THR B OG1 1 
ATOM 1030 C CG2 . THR B 1 6   ? 269.652 301.986 399.787 1.00 49.76  ? 5   THR B CG2 1 
ATOM 1031 N N   . VAL B 1 7   ? 273.847 301.623 397.686 1.00 46.36  ? 6   VAL B N   1 
ATOM 1032 C CA  . VAL B 1 7   ? 275.298 301.725 397.597 1.00 46.36  ? 6   VAL B CA  1 
ATOM 1033 C C   . VAL B 1 7   ? 275.650 303.181 397.884 1.00 46.36  ? 6   VAL B C   1 
ATOM 1034 O O   . VAL B 1 7   ? 275.663 304.016 396.983 1.00 46.36  ? 6   VAL B O   1 
ATOM 1035 C CB  . VAL B 1 7   ? 275.809 301.262 396.232 1.00 46.36  ? 6   VAL B CB  1 
ATOM 1036 C CG1 . VAL B 1 7   ? 277.318 301.303 396.173 1.00 46.36  ? 6   VAL B CG1 1 
ATOM 1037 C CG2 . VAL B 1 7   ? 275.311 299.873 395.943 1.00 46.36  ? 6   VAL B CG2 1 
ATOM 1038 N N   . THR B 1 8   ? 275.911 303.496 399.148 1.00 47.33  ? 7   THR B N   1 
ATOM 1039 C CA  . THR B 1 8   ? 276.226 304.859 399.562 1.00 47.33  ? 7   THR B CA  1 
ATOM 1040 C C   . THR B 1 8   ? 277.727 305.116 399.449 1.00 47.33  ? 7   THR B C   1 
ATOM 1041 O O   . THR B 1 8   ? 278.519 304.614 400.247 1.00 47.33  ? 7   THR B O   1 
ATOM 1042 C CB  . THR B 1 8   ? 275.694 305.146 400.973 1.00 47.33  ? 7   THR B CB  1 
ATOM 1043 O OG1 . THR B 1 8   ? 276.250 306.367 401.471 1.00 47.33  ? 7   THR B OG1 1 
ATOM 1044 C CG2 . THR B 1 8   ? 275.892 303.994 401.956 1.00 47.33  ? 7   THR B CG2 1 
ATOM 1045 N N   . LEU B 1 9   ? 278.113 305.913 398.464 1.00 43.89  ? 8   LEU B N   1 
ATOM 1046 C CA  . LEU B 1 9   ? 279.510 306.137 398.129 1.00 43.89  ? 8   LEU B CA  1 
ATOM 1047 C C   . LEU B 1 9   ? 279.977 307.422 398.792 1.00 43.89  ? 8   LEU B C   1 
ATOM 1048 O O   . LEU B 1 9   ? 279.300 308.446 398.699 1.00 43.89  ? 8   LEU B O   1 
ATOM 1049 C CB  . LEU B 1 9   ? 279.677 306.228 396.618 1.00 43.89  ? 8   LEU B CB  1 
ATOM 1050 C CG  . LEU B 1 9   ? 279.181 304.996 395.874 1.00 43.89  ? 8   LEU B CG  1 
ATOM 1051 C CD1 . LEU B 1 9   ? 279.148 305.262 394.398 1.00 43.89  ? 8   LEU B CD1 1 
ATOM 1052 C CD2 . LEU B 1 9   ? 280.076 303.834 396.177 1.00 43.89  ? 8   LEU B CD2 1 
ATOM 1053 N N   . GLY B 1 10  ? 281.128 307.365 399.466 1.00 47.81  ? 9   GLY B N   1 
ATOM 1054 C CA  . GLY B 1 10  ? 281.675 308.507 400.158 1.00 47.81  ? 9   GLY B CA  1 
ATOM 1055 C C   . GLY B 1 10  ? 283.055 308.859 399.628 1.00 47.81  ? 9   GLY B C   1 
ATOM 1056 O O   . GLY B 1 10  ? 283.672 308.095 398.875 1.00 47.81  ? 9   GLY B O   1 
ATOM 1057 N N   . ASN B 1 11  ? 283.530 310.038 400.046 1.00 51.12  ? 10  ASN B N   1 
ATOM 1058 C CA  . ASN B 1 11  ? 284.780 310.656 399.591 1.00 51.12  ? 10  ASN B CA  1 
ATOM 1059 C C   . ASN B 1 11  ? 284.807 310.796 398.067 1.00 51.12  ? 10  ASN B C   1 
ATOM 1060 O O   . ASN B 1 11  ? 285.649 310.231 397.370 1.00 51.12  ? 10  ASN B O   1 
ATOM 1061 C CB  . ASN B 1 11  ? 286.002 309.894 400.111 1.00 51.12  ? 10  ASN B CB  1 
ATOM 1062 C CG  . ASN B 1 11  ? 286.141 309.987 401.613 1.00 51.12  ? 10  ASN B CG  1 
ATOM 1063 O OD1 . ASN B 1 11  ? 285.904 311.040 402.204 1.00 51.12  ? 10  ASN B OD1 1 
ATOM 1064 N ND2 . ASN B 1 11  ? 286.524 308.883 402.242 1.00 51.12  ? 10  ASN B ND2 1 
ATOM 1065 N N   . ILE B 1 12  ? 283.848 311.562 397.567 1.00 47.36  ? 11  ILE B N   1 
ATOM 1066 C CA  . ILE B 1 12  ? 283.698 311.846 396.149 1.00 47.36  ? 11  ILE B CA  1 
ATOM 1067 C C   . ILE B 1 12  ? 283.964 313.330 395.951 1.00 47.36  ? 11  ILE B C   1 
ATOM 1068 O O   . ILE B 1 12  ? 283.697 314.143 396.838 1.00 47.36  ? 11  ILE B O   1 
ATOM 1069 C CB  . ILE B 1 12  ? 282.284 311.460 395.676 1.00 47.36  ? 11  ILE B CB  1 
ATOM 1070 C CG1 . ILE B 1 12  ? 281.977 310.027 396.045 1.00 47.36  ? 11  ILE B CG1 1 
ATOM 1071 C CG2 . ILE B 1 12  ? 282.155 311.517 394.182 1.00 47.36  ? 11  ILE B CG2 1 
ATOM 1072 C CD1 . ILE B 1 12  ? 280.548 309.700 395.836 1.00 47.36  ? 11  ILE B CD1 1 
ATOM 1073 N N   . GLY B 1 13  ? 284.521 313.684 394.804 1.00 46.93  ? 12  GLY B N   1 
ATOM 1074 C CA  . GLY B 1 13  ? 284.725 315.073 394.450 1.00 46.93  ? 12  GLY B CA  1 
ATOM 1075 C C   . GLY B 1 13  ? 286.194 315.410 394.293 1.00 46.93  ? 12  GLY B C   1 
ATOM 1076 O O   . GLY B 1 13  ? 287.086 314.650 394.658 1.00 46.93  ? 12  GLY B O   1 
ATOM 1077 N N   . LYS B 1 14  ? 286.418 316.589 393.713 1.00 51.16  ? 13  LYS B N   1 
ATOM 1078 C CA  . LYS B 1 14  ? 287.775 317.084 393.539 1.00 51.16  ? 13  LYS B CA  1 
ATOM 1079 C C   . LYS B 1 14  ? 288.424 317.391 394.882 1.00 51.16  ? 13  LYS B C   1 
ATOM 1080 O O   . LYS B 1 14  ? 289.632 317.192 395.047 1.00 51.16  ? 13  LYS B O   1 
ATOM 1081 C CB  . LYS B 1 14  ? 287.754 318.316 392.637 1.00 51.16  ? 13  LYS B CB  1 
ATOM 1082 C CG  . LYS B 1 14  ? 289.109 318.873 392.266 1.00 51.16  ? 13  LYS B CG  1 
ATOM 1083 C CD  . LYS B 1 14  ? 288.960 319.986 391.248 1.00 51.16  ? 13  LYS B CD  1 
ATOM 1084 C CE  . LYS B 1 14  ? 288.350 321.221 391.883 1.00 51.16  ? 13  LYS B CE  1 
ATOM 1085 N NZ  . LYS B 1 14  ? 288.301 322.361 390.932 1.00 51.16  ? 13  LYS B NZ  1 
ATOM 1086 N N   . ASP B 1 15  ? 287.639 317.845 395.860 1.00 56.24  ? 14  ASP B N   1 
ATOM 1087 C CA  . ASP B 1 15  ? 288.164 318.009 397.210 1.00 56.24  ? 14  ASP B CA  1 
ATOM 1088 C C   . ASP B 1 15  ? 288.123 316.703 397.998 1.00 56.24  ? 14  ASP B C   1 
ATOM 1089 O O   . ASP B 1 15  ? 289.073 316.382 398.718 1.00 56.24  ? 14  ASP B O   1 
ATOM 1090 C CB  . ASP B 1 15  ? 287.402 319.117 397.941 1.00 56.24  ? 14  ASP B CB  1 
ATOM 1091 C CG  . ASP B 1 15  ? 285.900 318.920 397.909 1.00 56.24  ? 14  ASP B CG  1 
ATOM 1092 O OD1 . ASP B 1 15  ? 285.429 318.001 397.212 1.00 56.24  ? 14  ASP B OD1 1 
ATOM 1093 O OD2 . ASP B 1 15  ? 285.186 319.684 398.591 1.00 56.24  ? 14  ASP B OD2 1 
ATOM 1094 N N   . GLY B 1 16  ? 287.047 315.937 397.872 1.00 55.04  ? 15  GLY B N   1 
ATOM 1095 C CA  . GLY B 1 16  ? 286.915 314.680 398.567 1.00 55.04  ? 15  GLY B CA  1 
ATOM 1096 C C   . GLY B 1 16  ? 286.047 314.704 399.802 1.00 55.04  ? 15  GLY B C   1 
ATOM 1097 O O   . GLY B 1 16  ? 286.373 314.017 400.775 1.00 55.04  ? 15  GLY B O   1 
ATOM 1098 N N   . LYS B 1 17  ? 284.949 315.461 399.794 1.00 57.79  ? 16  LYS B N   1 
ATOM 1099 C CA  . LYS B 1 17  ? 284.068 315.567 400.947 1.00 57.79  ? 16  LYS B CA  1 
ATOM 1100 C C   . LYS B 1 17  ? 282.618 315.250 400.611 1.00 57.79  ? 16  LYS B C   1 
ATOM 1101 O O   . LYS B 1 17  ? 281.771 315.282 401.508 1.00 57.79  ? 16  LYS B O   1 
ATOM 1102 C CB  . LYS B 1 17  ? 284.141 316.971 401.548 1.00 57.79  ? 16  LYS B CB  1 
ATOM 1103 C CG  . LYS B 1 17  ? 285.472 317.329 402.172 1.00 57.79  ? 16  LYS B CG  1 
ATOM 1104 C CD  . LYS B 1 17  ? 285.416 318.734 402.744 1.00 57.79  ? 16  LYS B CD  1 
ATOM 1105 C CE  . LYS B 1 17  ? 286.741 319.143 403.352 1.00 57.79  ? 16  LYS B CE  1 
ATOM 1106 N NZ  . LYS B 1 17  ? 286.676 320.521 403.909 1.00 57.79  ? 16  LYS B NZ  1 
ATOM 1107 N N   . GLN B 1 18  ? 282.307 314.955 399.356 1.00 54.27  ? 17  GLN B N   1 
ATOM 1108 C CA  . GLN B 1 18  ? 280.933 314.776 398.917 1.00 54.27  ? 17  GLN B CA  1 
ATOM 1109 C C   . GLN B 1 18  ? 280.563 313.301 398.945 1.00 54.27  ? 17  GLN B C   1 
ATOM 1110 O O   . GLN B 1 18  ? 281.414 312.431 398.760 1.00 54.27  ? 17  GLN B O   1 
ATOM 1111 C CB  . GLN B 1 18  ? 280.745 315.333 397.508 1.00 54.27  ? 17  GLN B CB  1 
ATOM 1112 C CG  . GLN B 1 18  ? 281.079 316.798 397.389 1.00 54.27  ? 17  GLN B CG  1 
ATOM 1113 C CD  . GLN B 1 18  ? 280.955 317.301 395.974 1.00 54.27  ? 17  GLN B CD  1 
ATOM 1114 O OE1 . GLN B 1 18  ? 280.622 316.547 395.064 1.00 54.27  ? 17  GLN B OE1 1 
ATOM 1115 N NE2 . GLN B 1 18  ? 281.239 318.578 395.774 1.00 54.27  ? 17  GLN B NE2 1 
ATOM 1116 N N   . THR B 1 19  ? 279.287 313.025 399.202 1.00 54.89  ? 18  THR B N   1 
ATOM 1117 C CA  . THR B 1 19  ? 278.762 311.668 399.188 1.00 54.89  ? 18  THR B CA  1 
ATOM 1118 C C   . THR B 1 19  ? 277.595 311.572 398.220 1.00 54.89  ? 18  THR B C   1 
ATOM 1119 O O   . THR B 1 19  ? 277.040 312.582 397.787 1.00 54.89  ? 18  THR B O   1 
ATOM 1120 C CB  . THR B 1 19  ? 278.292 311.206 400.567 1.00 54.89  ? 18  THR B CB  1 
ATOM 1121 O OG1 . THR B 1 19  ? 277.235 312.053 401.023 1.00 54.89  ? 18  THR B OG1 1 
ATOM 1122 C CG2 . THR B 1 19  ? 279.423 311.224 401.566 1.00 54.89  ? 18  THR B CG2 1 
ATOM 1123 N N   . LEU B 1 20  ? 277.230 310.340 397.889 1.00 45.94  ? 19  LEU B N   1 
ATOM 1124 C CA  . LEU B 1 20  ? 276.145 310.064 396.963 1.00 45.94  ? 19  LEU B CA  1 
ATOM 1125 C C   . LEU B 1 20  ? 275.525 308.730 397.325 1.00 45.94  ? 19  LEU B C   1 
ATOM 1126 O O   . LEU B 1 20  ? 276.236 307.728 397.418 1.00 45.94  ? 19  LEU B O   1 
ATOM 1127 C CB  . LEU B 1 20  ? 276.653 310.034 395.523 1.00 45.94  ? 19  LEU B CB  1 
ATOM 1128 C CG  . LEU B 1 20  ? 275.597 309.652 394.496 1.00 45.94  ? 19  LEU B CG  1 
ATOM 1129 C CD1 . LEU B 1 20  ? 274.476 310.666 394.479 1.00 45.94  ? 19  LEU B CD1 1 
ATOM 1130 C CD2 . LEU B 1 20  ? 276.206 309.511 393.129 1.00 45.94  ? 19  LEU B CD2 1 
ATOM 1131 N N   . VAL B 1 21  ? 274.211 308.708 397.524 1.00 46.06  ? 20  VAL B N   1 
ATOM 1132 C CA  . VAL B 1 21  ? 273.495 307.478 397.839 1.00 46.06  ? 20  VAL B CA  1 
ATOM 1133 C C   . VAL B 1 21  ? 272.661 307.065 396.631 1.00 46.06  ? 20  VAL B C   1 
ATOM 1134 O O   . VAL B 1 21  ? 272.030 307.898 395.971 1.00 46.06  ? 20  VAL B O   1 
ATOM 1135 C CB  . VAL B 1 21  ? 272.652 307.619 399.127 1.00 46.06  ? 20  VAL B CB  1 
ATOM 1136 C CG1 . VAL B 1 21  ? 271.588 308.693 399.016 1.00 46.06  ? 20  VAL B CG1 1 
ATOM 1137 C CG2 . VAL B 1 21  ? 272.021 306.299 399.499 1.00 46.06  ? 20  VAL B CG2 1 
ATOM 1138 N N   . LEU B 1 22  ? 272.716 305.780 396.302 1.00 41.90  ? 21  LEU B N   1 
ATOM 1139 C CA  . LEU B 1 22  ? 272.068 305.235 395.121 1.00 41.90  ? 21  LEU B CA  1 
ATOM 1140 C C   . LEU B 1 22  ? 271.040 304.210 395.562 1.00 41.90  ? 21  LEU B C   1 
ATOM 1141 O O   . LEU B 1 22  ? 271.397 303.182 396.139 1.00 41.90  ? 21  LEU B O   1 
ATOM 1142 C CB  . LEU B 1 22  ? 273.101 304.605 394.191 1.00 41.90  ? 21  LEU B CB  1 
ATOM 1143 C CG  . LEU B 1 22  ? 274.092 305.562 393.546 1.00 41.90  ? 21  LEU B CG  1 
ATOM 1144 C CD1 . LEU B 1 22  ? 275.176 304.779 392.883 1.00 41.90  ? 21  LEU B CD1 1 
ATOM 1145 C CD2 . LEU B 1 22  ? 273.374 306.418 392.533 1.00 41.90  ? 21  LEU B CD2 1 
ATOM 1146 N N   . ASN B 1 23  ? 269.790 304.480 395.285 1.00 43.74  ? 22  ASN B N   1 
ATOM 1147 C CA  . ASN B 1 23  ? 268.694 303.622 395.701 1.00 43.74  ? 22  ASN B CA  1 
ATOM 1148 C C   . ASN B 1 23  ? 268.299 302.695 394.567 1.00 43.74  ? 22  ASN B C   1 
ATOM 1149 O O   . ASN B 1 23  ? 268.169 303.155 393.426 1.00 43.74  ? 22  ASN B O   1 
ATOM 1150 C CB  . ASN B 1 23  ? 267.503 304.468 396.122 1.00 43.74  ? 22  ASN B CB  1 
ATOM 1151 C CG  . ASN B 1 23  ? 267.799 305.310 397.334 1.00 43.74  ? 22  ASN B CG  1 
ATOM 1152 O OD1 . ASN B 1 23  ? 267.859 306.533 397.255 1.00 43.74  ? 22  ASN B OD1 1 
ATOM 1153 N ND2 . ASN B 1 23  ? 267.978 304.662 398.468 1.00 43.74  ? 22  ASN B ND2 1 
ATOM 1154 N N   . PRO B 1 24  ? 268.091 301.409 394.833 1.00 41.40  ? 23  PRO B N   1 
ATOM 1155 C CA  . PRO B 1 24  ? 267.941 300.440 393.746 1.00 41.40  ? 23  PRO B CA  1 
ATOM 1156 C C   . PRO B 1 24  ? 266.597 300.543 393.049 1.00 41.40  ? 23  PRO B C   1 
ATOM 1157 O O   . PRO B 1 24  ? 265.574 300.847 393.661 1.00 41.40  ? 23  PRO B O   1 
ATOM 1158 C CB  . PRO B 1 24  ? 268.086 299.096 394.460 1.00 41.40  ? 23  PRO B CB  1 
ATOM 1159 C CG  . PRO B 1 24  ? 267.668 299.369 395.838 1.00 41.40  ? 23  PRO B CG  1 
ATOM 1160 C CD  . PRO B 1 24  ? 268.075 300.763 396.152 1.00 41.40  ? 23  PRO B CD  1 
ATOM 1161 N N   . ARG B 1 25  ? 266.612 300.283 391.740 1.00 39.53  ? 24  ARG B N   1 
ATOM 1162 C CA  . ARG B 1 25  ? 265.426 300.411 390.901 1.00 39.53  ? 24  ARG B CA  1 
ATOM 1163 C C   . ARG B 1 25  ? 265.184 299.147 390.087 1.00 39.53  ? 24  ARG B C   1 
ATOM 1164 O O   . ARG B 1 25  ? 264.703 299.217 388.956 1.00 39.53  ? 24  ARG B O   1 
ATOM 1165 C CB  . ARG B 1 25  ? 265.539 301.620 389.976 1.00 39.53  ? 24  ARG B CB  1 
ATOM 1166 C CG  . ARG B 1 25  ? 265.615 302.961 390.685 1.00 39.53  ? 24  ARG B CG  1 
ATOM 1167 C CD  . ARG B 1 25  ? 264.284 303.398 391.257 1.00 39.53  ? 24  ARG B CD  1 
ATOM 1168 N NE  . ARG B 1 25  ? 263.299 303.590 390.201 1.00 39.53  ? 24  ARG B NE  1 
ATOM 1169 C CZ  . ARG B 1 25  ? 263.163 304.715 389.511 1.00 39.53  ? 24  ARG B CZ  1 
ATOM 1170 N NH1 . ARG B 1 25  ? 263.946 305.749 389.768 1.00 39.53  ? 24  ARG B NH1 1 
ATOM 1171 N NH2 . ARG B 1 25  ? 262.248 304.805 388.561 1.00 39.53  ? 24  ARG B NH2 1 
ATOM 1172 N N   . GLY B 1 26  ? 265.518 297.987 390.637 1.00 37.67  ? 25  GLY B N   1 
ATOM 1173 C CA  . GLY B 1 26  ? 265.152 296.723 390.034 1.00 37.67  ? 25  GLY B CA  1 
ATOM 1174 C C   . GLY B 1 26  ? 266.033 296.310 388.871 1.00 37.67  ? 25  GLY B C   1 
ATOM 1175 O O   . GLY B 1 26  ? 266.873 297.057 388.379 1.00 37.67  ? 25  GLY B O   1 
ATOM 1176 N N   . VAL B 1 27  ? 265.803 295.082 388.410 1.00 35.59  ? 26  VAL B N   1 
ATOM 1177 C CA  . VAL B 1 27  ? 266.570 294.455 387.341 1.00 35.59  ? 26  VAL B CA  1 
ATOM 1178 C C   . VAL B 1 27  ? 265.665 294.314 386.127 1.00 35.59  ? 26  VAL B C   1 
ATOM 1179 O O   . VAL B 1 27  ? 264.520 293.872 386.252 1.00 35.59  ? 26  VAL B O   1 
ATOM 1180 C CB  . VAL B 1 27  ? 267.111 293.085 387.784 1.00 35.59  ? 26  VAL B CB  1 
ATOM 1181 C CG1 . VAL B 1 27  ? 267.913 292.433 386.685 1.00 35.59  ? 26  VAL B CG1 1 
ATOM 1182 C CG2 . VAL B 1 27  ? 267.944 293.229 389.028 1.00 35.59  ? 26  VAL B CG2 1 
ATOM 1183 N N   . ASN B 1 28  ? 266.169 294.692 384.962 1.00 35.25  ? 27  ASN B N   1 
ATOM 1184 C CA  . ASN B 1 28  ? 265.413 294.562 383.724 1.00 35.25  ? 27  ASN B CA  1 
ATOM 1185 C C   . ASN B 1 28  ? 265.530 293.130 383.215 1.00 35.25  ? 27  ASN B C   1 
ATOM 1186 O O   . ASN B 1 28  ? 266.643 292.682 382.931 1.00 35.25  ? 27  ASN B O   1 
ATOM 1187 C CB  . ASN B 1 28  ? 265.956 295.538 382.688 1.00 35.25  ? 27  ASN B CB  1 
ATOM 1188 C CG  . ASN B 1 28  ? 265.067 295.674 381.472 1.00 35.25  ? 27  ASN B CG  1 
ATOM 1189 O OD1 . ASN B 1 28  ? 263.997 295.078 381.394 1.00 35.25  ? 27  ASN B OD1 1 
ATOM 1190 N ND2 . ASN B 1 28  ? 265.516 296.461 380.508 1.00 35.25  ? 27  ASN B ND2 1 
ATOM 1191 N N   . PRO B 1 29  ? 264.428 292.387 383.086 1.00 37.34  ? 28  PRO B N   1 
ATOM 1192 C CA  . PRO B 1 29  ? 264.543 290.986 382.655 1.00 37.34  ? 28  PRO B CA  1 
ATOM 1193 C C   . PRO B 1 29  ? 264.859 290.835 381.185 1.00 37.34  ? 28  PRO B C   1 
ATOM 1194 O O   . PRO B 1 29  ? 265.322 289.766 380.772 1.00 37.34  ? 28  PRO B O   1 
ATOM 1195 C CB  . PRO B 1 29  ? 263.161 290.405 382.975 1.00 37.34  ? 28  PRO B CB  1 
ATOM 1196 C CG  . PRO B 1 29  ? 262.555 291.361 383.943 1.00 37.34  ? 28  PRO B CG  1 
ATOM 1197 C CD  . PRO B 1 29  ? 263.064 292.698 383.532 1.00 37.34  ? 28  PRO B CD  1 
ATOM 1198 N N   . THR B 1 30  ? 264.624 291.876 380.390 1.00 39.68  ? 29  THR B N   1 
ATOM 1199 C CA  . THR B 1 30  ? 264.790 291.796 378.945 1.00 39.68  ? 29  THR B CA  1 
ATOM 1200 C C   . THR B 1 30  ? 266.261 291.712 378.552 1.00 39.68  ? 29  THR B C   1 
ATOM 1201 O O   . THR B 1 30  ? 266.603 291.068 377.555 1.00 39.68  ? 29  THR B O   1 
ATOM 1202 C CB  . THR B 1 30  ? 264.107 293.010 378.309 1.00 39.68  ? 29  THR B CB  1 
ATOM 1203 O OG1 . THR B 1 30  ? 262.754 293.078 378.772 1.00 39.68  ? 29  THR B OG1 1 
ATOM 1204 C CG2 . THR B 1 30  ? 264.080 292.914 376.798 1.00 39.68  ? 29  THR B CG2 1 
ATOM 1205 N N   . ASN B 1 31  ? 267.147 292.322 379.330 1.00 38.94  ? 30  ASN B N   1 
ATOM 1206 C CA  . ASN B 1 31  ? 268.570 292.253 379.037 1.00 38.94  ? 30  ASN B CA  1 
ATOM 1207 C C   . ASN B 1 31  ? 269.454 292.004 380.250 1.00 38.94  ? 30  ASN B C   1 
ATOM 1208 O O   . ASN B 1 31  ? 270.676 291.954 380.091 1.00 38.94  ? 30  ASN B O   1 
ATOM 1209 C CB  . ASN B 1 31  ? 269.020 293.532 378.315 1.00 38.94  ? 30  ASN B CB  1 
ATOM 1210 C CG  . ASN B 1 31  ? 268.587 294.790 379.028 1.00 38.94  ? 30  ASN B CG  1 
ATOM 1211 O OD1 . ASN B 1 31  ? 268.014 294.741 380.112 1.00 38.94  ? 30  ASN B OD1 1 
ATOM 1212 N ND2 . ASN B 1 31  ? 268.858 295.931 378.419 1.00 38.94  ? 30  ASN B ND2 1 
ATOM 1213 N N   . GLY B 1 32  ? 268.892 291.836 381.440 1.00 35.91  ? 31  GLY B N   1 
ATOM 1214 C CA  . GLY B 1 32  ? 269.688 291.513 382.610 1.00 35.91  ? 31  GLY B CA  1 
ATOM 1215 C C   . GLY B 1 32  ? 270.536 292.651 383.126 1.00 35.91  ? 31  GLY B C   1 
ATOM 1216 O O   . GLY B 1 32  ? 271.682 292.431 383.529 1.00 35.91  ? 31  GLY B O   1 
ATOM 1217 N N   . VAL B 1 33  ? 269.993 293.859 383.140 1.00 33.90  ? 32  VAL B N   1 
ATOM 1218 C CA  . VAL B 1 33  ? 270.723 295.059 383.519 1.00 33.90  ? 32  VAL B CA  1 
ATOM 1219 C C   . VAL B 1 33  ? 270.171 295.548 384.846 1.00 33.90  ? 32  VAL B C   1 
ATOM 1220 O O   . VAL B 1 33  ? 269.011 295.966 384.927 1.00 33.90  ? 32  VAL B O   1 
ATOM 1221 C CB  . VAL B 1 33  ? 270.611 296.141 382.444 1.00 33.90  ? 32  VAL B CB  1 
ATOM 1222 C CG1 . VAL B 1 33  ? 271.248 297.406 382.916 1.00 33.90  ? 32  VAL B CG1 1 
ATOM 1223 C CG2 . VAL B 1 33  ? 271.273 295.676 381.179 1.00 33.90  ? 32  VAL B CG2 1 
ATOM 1224 N N   . ALA B 1 34  ? 270.988 295.484 385.889 1.00 33.66  ? 33  ALA B N   1 
ATOM 1225 C CA  . ALA B 1 34  ? 270.616 296.044 387.173 1.00 33.66  ? 33  ALA B CA  1 
ATOM 1226 C C   . ALA B 1 34  ? 270.624 297.563 387.097 1.00 33.66  ? 33  ALA B C   1 
ATOM 1227 O O   . ALA B 1 34  ? 271.228 298.162 386.209 1.00 33.66  ? 33  ALA B O   1 
ATOM 1228 C CB  . ALA B 1 34  ? 271.573 295.577 388.264 1.00 33.66  ? 33  ALA B CB  1 
ATOM 1229 N N   . SER B 1 35  ? 269.952 298.194 388.052 1.00 37.62  ? 34  SER B N   1 
ATOM 1230 C CA  . SER B 1 35  ? 269.782 299.637 387.994 1.00 37.62  ? 34  SER B CA  1 
ATOM 1231 C C   . SER B 1 35  ? 269.812 300.227 389.390 1.00 37.62  ? 34  SER B C   1 
ATOM 1232 O O   . SER B 1 35  ? 269.097 299.761 390.277 1.00 37.62  ? 34  SER B O   1 
ATOM 1233 C CB  . SER B 1 35  ? 268.470 300.004 387.304 1.00 37.62  ? 34  SER B CB  1 
ATOM 1234 O OG  . SER B 1 35  ? 268.464 299.583 385.954 1.00 37.62  ? 34  SER B OG  1 
ATOM 1235 N N   . LEU B 1 36  ? 270.643 301.245 389.572 1.00 36.16  ? 35  LEU B N   1 
ATOM 1236 C CA  . LEU B 1 36  ? 270.638 302.091 390.751 1.00 36.16  ? 35  LEU B CA  1 
ATOM 1237 C C   . LEU B 1 36  ? 270.341 303.509 390.306 1.00 36.16  ? 35  LEU B C   1 
ATOM 1238 O O   . LEU B 1 36  ? 270.657 303.888 389.180 1.00 36.16  ? 35  LEU B O   1 
ATOM 1239 C CB  . LEU B 1 36  ? 271.975 302.063 391.470 1.00 36.16  ? 35  LEU B CB  1 
ATOM 1240 C CG  . LEU B 1 36  ? 272.474 300.762 392.074 1.00 36.16  ? 35  LEU B CG  1 
ATOM 1241 C CD1 . LEU B 1 36  ? 273.898 300.960 392.487 1.00 36.16  ? 35  LEU B CD1 1 
ATOM 1242 C CD2 . LEU B 1 36  ? 271.667 300.388 393.271 1.00 36.16  ? 35  LEU B CD2 1 
ATOM 1243 N N   . SER B 1 37  ? 269.715 304.288 391.177 1.00 39.44  ? 36  SER B N   1 
ATOM 1244 C CA  . SER B 1 37  ? 269.386 305.664 390.846 1.00 39.44  ? 36  SER B CA  1 
ATOM 1245 C C   . SER B 1 37  ? 269.369 306.491 392.117 1.00 39.44  ? 36  SER B C   1 
ATOM 1246 O O   . SER B 1 37  ? 269.396 305.960 393.227 1.00 39.44  ? 36  SER B O   1 
ATOM 1247 C CB  . SER B 1 37  ? 268.044 305.769 390.132 1.00 39.44  ? 36  SER B CB  1 
ATOM 1248 O OG  . SER B 1 37  ? 267.739 307.120 389.860 1.00 39.44  ? 36  SER B OG  1 
ATOM 1249 N N   . GLN B 1 38  ? 269.298 307.802 391.940 1.00 42.12  ? 37  GLN B N   1 
ATOM 1250 C CA  . GLN B 1 38  ? 269.327 308.743 393.046 1.00 42.12  ? 37  GLN B CA  1 
ATOM 1251 C C   . GLN B 1 38  ? 267.893 308.903 393.562 1.00 42.12  ? 37  GLN B C   1 
ATOM 1252 O O   . GLN B 1 38  ? 266.986 308.175 393.155 1.00 42.12  ? 37  GLN B O   1 
ATOM 1253 C CB  . GLN B 1 38  ? 269.962 310.049 392.574 1.00 42.12  ? 37  GLN B CB  1 
ATOM 1254 C CG  . GLN B 1 38  ? 270.621 310.895 393.640 1.00 42.12  ? 37  GLN B CG  1 
ATOM 1255 C CD  . GLN B 1 38  ? 271.107 312.212 393.104 1.00 42.12  ? 37  GLN B CD  1 
ATOM 1256 O OE1 . GLN B 1 38  ? 270.821 312.571 391.964 1.00 42.12  ? 37  GLN B OE1 1 
ATOM 1257 N NE2 . GLN B 1 38  ? 271.866 312.936 393.912 1.00 42.12  ? 37  GLN B NE2 1 
ATOM 1258 N N   . ALA B 1 39  ? 267.655 309.857 394.458 1.00 46.32  ? 38  ALA B N   1 
ATOM 1259 C CA  . ALA B 1 39  ? 266.367 309.990 395.125 1.00 46.32  ? 38  ALA B CA  1 
ATOM 1260 C C   . ALA B 1 39  ? 265.566 311.188 394.629 1.00 46.32  ? 38  ALA B C   1 
ATOM 1261 O O   . ALA B 1 39  ? 264.811 311.790 395.392 1.00 46.32  ? 38  ALA B O   1 
ATOM 1262 C CB  . ALA B 1 39  ? 266.562 310.075 396.635 1.00 46.32  ? 38  ALA B CB  1 
ATOM 1263 N N   . GLY B 1 40  ? 265.715 311.544 393.359 1.00 46.46  ? 39  GLY B N   1 
ATOM 1264 C CA  . GLY B 1 40  ? 264.929 312.627 392.809 1.00 46.46  ? 39  GLY B CA  1 
ATOM 1265 C C   . GLY B 1 40  ? 263.492 312.220 392.546 1.00 46.46  ? 39  GLY B C   1 
ATOM 1266 O O   . GLY B 1 40  ? 263.130 311.044 392.560 1.00 46.46  ? 39  GLY B O   1 
ATOM 1267 N N   . ALA B 1 41  ? 262.649 313.225 392.314 1.00 45.18  ? 40  ALA B N   1 
ATOM 1268 C CA  . ALA B 1 41  ? 261.263 312.956 391.947 1.00 45.18  ? 40  ALA B CA  1 
ATOM 1269 C C   . ALA B 1 41  ? 261.107 312.867 390.436 1.00 45.18  ? 40  ALA B C   1 
ATOM 1270 O O   . ALA B 1 41  ? 260.551 311.894 389.915 1.00 45.18  ? 40  ALA B O   1 
ATOM 1271 C CB  . ALA B 1 41  ? 260.347 314.040 392.515 1.00 45.18  ? 40  ALA B CB  1 
ATOM 1272 N N   . VAL B 1 42  ? 261.587 313.880 389.727 1.00 39.48  ? 41  VAL B N   1 
ATOM 1273 C CA  . VAL B 1 42  ? 261.578 313.890 388.262 1.00 39.48  ? 41  VAL B CA  1 
ATOM 1274 C C   . VAL B 1 42  ? 262.595 312.872 387.755 1.00 39.48  ? 41  VAL B C   1 
ATOM 1275 O O   . VAL B 1 42  ? 263.755 312.898 388.191 1.00 39.48  ? 41  VAL B O   1 
ATOM 1276 C CB  . VAL B 1 42  ? 261.900 315.289 387.750 1.00 39.48  ? 41  VAL B CB  1 
ATOM 1277 C CG1 . VAL B 1 42  ? 261.930 315.314 386.248 1.00 39.48  ? 41  VAL B CG1 1 
ATOM 1278 C CG2 . VAL B 1 42  ? 260.898 316.273 388.275 1.00 39.48  ? 41  VAL B CG2 1 
ATOM 1279 N N   . PRO B 1 43  ? 262.216 311.960 386.855 1.00 36.96  ? 42  PRO B N   1 
ATOM 1280 C CA  . PRO B 1 43  ? 263.154 310.922 386.411 1.00 36.96  ? 42  PRO B CA  1 
ATOM 1281 C C   . PRO B 1 43  ? 264.258 311.393 385.485 1.00 36.96  ? 42  PRO B C   1 
ATOM 1282 O O   . PRO B 1 43  ? 265.207 310.633 385.266 1.00 36.96  ? 42  PRO B O   1 
ATOM 1283 C CB  . PRO B 1 43  ? 262.245 309.924 385.691 1.00 36.96  ? 42  PRO B CB  1 
ATOM 1284 C CG  . PRO B 1 43  ? 261.091 310.700 385.276 1.00 36.96  ? 42  PRO B CG  1 
ATOM 1285 C CD  . PRO B 1 43  ? 260.864 311.722 386.335 1.00 36.96  ? 42  PRO B CD  1 
ATOM 1286 N N   . ALA B 1 44  ? 264.184 312.595 384.928 1.00 36.98  ? 43  ALA B N   1 
ATOM 1287 C CA  . ALA B 1 44  ? 265.239 313.057 384.039 1.00 36.98  ? 43  ALA B CA  1 
ATOM 1288 C C   . ALA B 1 44  ? 266.340 313.815 384.760 1.00 36.98  ? 43  ALA B C   1 
ATOM 1289 O O   . ALA B 1 44  ? 267.310 314.217 384.118 1.00 36.98  ? 43  ALA B O   1 
ATOM 1290 C CB  . ALA B 1 44  ? 264.660 313.949 382.941 1.00 36.98  ? 43  ALA B CB  1 
ATOM 1291 N N   . LEU B 1 45  ? 266.216 314.017 386.069 1.00 40.52  ? 44  LEU B N   1 
ATOM 1292 C CA  . LEU B 1 45  ? 267.205 314.743 386.848 1.00 40.52  ? 44  LEU B CA  1 
ATOM 1293 C C   . LEU B 1 45  ? 267.977 313.829 387.788 1.00 40.52  ? 44  LEU B C   1 
ATOM 1294 O O   . LEU B 1 45  ? 268.640 314.310 388.709 1.00 40.52  ? 44  LEU B O   1 
ATOM 1295 C CB  . LEU B 1 45  ? 266.530 315.858 387.643 1.00 40.52  ? 44  LEU B CB  1 
ATOM 1296 C CG  . LEU B 1 45  ? 265.791 316.917 386.829 1.00 40.52  ? 44  LEU B CG  1 
ATOM 1297 C CD1 . LEU B 1 45  ? 265.097 317.907 387.736 1.00 40.52  ? 44  LEU B CD1 1 
ATOM 1298 C CD2 . LEU B 1 45  ? 266.751 317.624 385.939 1.00 40.52  ? 44  LEU B CD2 1 
ATOM 1299 N N   . GLU B 1 46  ? 267.902 312.523 387.575 1.00 39.42  ? 45  GLU B N   1 
ATOM 1300 C CA  . GLU B 1 46  ? 268.515 311.544 388.453 1.00 39.42  ? 45  GLU B CA  1 
ATOM 1301 C C   . GLU B 1 46  ? 269.890 311.138 387.948 1.00 39.42  ? 45  GLU B C   1 
ATOM 1302 O O   . GLU B 1 46  ? 270.131 311.064 386.742 1.00 39.42  ? 45  GLU B O   1 
ATOM 1303 C CB  . GLU B 1 46  ? 267.637 310.300 388.572 1.00 39.42  ? 45  GLU B CB  1 
ATOM 1304 C CG  . GLU B 1 46  ? 266.359 310.509 389.349 1.00 39.42  ? 45  GLU B CG  1 
ATOM 1305 C CD  . GLU B 1 46  ? 265.499 309.266 389.382 1.00 39.42  ? 45  GLU B CD  1 
ATOM 1306 O OE1 . GLU B 1 46  ? 265.839 308.297 388.674 1.00 39.42  ? 45  GLU B OE1 1 
ATOM 1307 O OE2 . GLU B 1 46  ? 264.491 309.250 390.118 1.00 39.42  ? 45  GLU B OE2 1 
ATOM 1308 N N   . LYS B 1 47  ? 270.788 310.859 388.886 1.00 36.26  ? 46  LYS B N   1 
ATOM 1309 C CA  . LYS B 1 47  ? 272.082 310.263 388.582 1.00 36.26  ? 46  LYS B CA  1 
ATOM 1310 C C   . LYS B 1 47  ? 271.931 308.757 388.721 1.00 36.26  ? 46  LYS B C   1 
ATOM 1311 O O   . LYS B 1 47  ? 271.716 308.256 389.825 1.00 36.26  ? 46  LYS B O   1 
ATOM 1312 C CB  . LYS B 1 47  ? 273.153 310.770 389.539 1.00 36.26  ? 46  LYS B CB  1 
ATOM 1313 C CG  . LYS B 1 47  ? 273.379 312.256 389.536 1.00 36.26  ? 46  LYS B CG  1 
ATOM 1314 C CD  . LYS B 1 47  ? 274.483 312.621 390.517 1.00 36.26  ? 46  LYS B CD  1 
ATOM 1315 C CE  . LYS B 1 47  ? 274.607 314.115 390.671 1.00 36.26  ? 46  LYS B CE  1 
ATOM 1316 N NZ  . LYS B 1 47  ? 275.025 314.752 389.402 1.00 36.26  ? 46  LYS B NZ  1 
ATOM 1317 N N   . ARG B 1 48  ? 272.050 308.028 387.619 1.00 35.17  ? 47  ARG B N   1 
ATOM 1318 C CA  . ARG B 1 48  ? 271.806 306.596 387.646 1.00 35.17  ? 47  ARG B CA  1 
ATOM 1319 C C   . ARG B 1 48  ? 273.032 305.809 387.210 1.00 35.17  ? 47  ARG B C   1 
ATOM 1320 O O   . ARG B 1 48  ? 273.858 306.285 386.434 1.00 35.17  ? 47  ARG B O   1 
ATOM 1321 C CB  . ARG B 1 48  ? 270.594 306.205 386.786 1.00 35.17  ? 47  ARG B CB  1 
ATOM 1322 C CG  . ARG B 1 48  ? 270.751 306.289 385.285 1.00 35.17  ? 47  ARG B CG  1 
ATOM 1323 C CD  . ARG B 1 48  ? 270.432 307.677 384.773 1.00 35.17  ? 47  ARG B CD  1 
ATOM 1324 N NE  . ARG B 1 48  ? 269.114 308.121 385.216 1.00 35.17  ? 47  ARG B NE  1 
ATOM 1325 C CZ  . ARG B 1 48  ? 267.971 307.812 384.613 1.00 35.17  ? 47  ARG B CZ  1 
ATOM 1326 N NH1 . ARG B 1 48  ? 267.970 307.057 383.524 1.00 35.17  ? 47  ARG B NH1 1 
ATOM 1327 N NH2 . ARG B 1 48  ? 266.824 308.264 385.097 1.00 35.17  ? 47  ARG B NH2 1 
ATOM 1328 N N   . VAL B 1 49  ? 273.137 304.596 387.753 1.00 31.27  ? 48  VAL B N   1 
ATOM 1329 C CA  . VAL B 1 49  ? 274.220 303.656 387.495 1.00 31.27  ? 48  VAL B CA  1 
ATOM 1330 C C   . VAL B 1 49  ? 273.590 302.336 387.072 1.00 31.27  ? 48  VAL B C   1 
ATOM 1331 O O   . VAL B 1 49  ? 272.670 301.853 387.736 1.00 31.27  ? 48  VAL B O   1 
ATOM 1332 C CB  . VAL B 1 49  ? 275.096 303.448 388.746 1.00 31.27  ? 48  VAL B CB  1 
ATOM 1333 C CG1 . VAL B 1 49  ? 276.137 302.385 388.505 1.00 31.27  ? 48  VAL B CG1 1 
ATOM 1334 C CG2 . VAL B 1 49  ? 275.753 304.738 389.174 1.00 31.27  ? 48  VAL B CG2 1 
ATOM 1335 N N   . THR B 1 50  ? 274.072 301.755 385.977 1.00 30.92  ? 49  THR B N   1 
ATOM 1336 C CA  . THR B 1 50  ? 273.653 300.426 385.556 1.00 30.92  ? 49  THR B CA  1 
ATOM 1337 C C   . THR B 1 50  ? 274.852 299.488 385.535 1.00 30.92  ? 49  THR B C   1 
ATOM 1338 O O   . THR B 1 50  ? 275.993 299.927 385.393 1.00 30.92  ? 49  THR B O   1 
ATOM 1339 C CB  . THR B 1 50  ? 273.002 300.451 384.178 1.00 30.92  ? 49  THR B CB  1 
ATOM 1340 O OG1 . THR B 1 50  ? 273.943 300.922 383.213 1.00 30.92  ? 49  THR B OG1 1 
ATOM 1341 C CG2 . THR B 1 50  ? 271.789 301.353 384.171 1.00 30.92  ? 49  THR B CG2 1 
ATOM 1342 N N   . VAL B 1 51  ? 274.593 298.190 385.677 1.00 30.14  ? 50  VAL B N   1 
ATOM 1343 C CA  . VAL B 1 51  ? 275.648 297.179 385.752 1.00 30.14  ? 50  VAL B CA  1 
ATOM 1344 C C   . VAL B 1 51  ? 275.076 295.845 385.287 1.00 30.14  ? 50  VAL B C   1 
ATOM 1345 O O   . VAL B 1 51  ? 273.963 295.474 385.662 1.00 30.14  ? 50  VAL B O   1 
ATOM 1346 C CB  . VAL B 1 51  ? 276.254 297.105 387.174 1.00 30.14  ? 50  VAL B CB  1 
ATOM 1347 C CG1 . VAL B 1 51  ? 275.196 296.963 388.231 1.00 30.14  ? 50  VAL B CG1 1 
ATOM 1348 C CG2 . VAL B 1 51  ? 277.240 295.957 387.303 1.00 30.14  ? 50  VAL B CG2 1 
ATOM 1349 N N   . SER B 1 52  ? 275.811 295.142 384.428 1.00 31.83  ? 51  SER B N   1 
ATOM 1350 C CA  . SER B 1 52  ? 275.319 293.887 383.885 1.00 31.83  ? 51  SER B CA  1 
ATOM 1351 C C   . SER B 1 52  ? 276.485 293.006 383.483 1.00 31.83  ? 51  SER B C   1 
ATOM 1352 O O   . SER B 1 52  ? 277.438 293.478 382.864 1.00 31.83  ? 51  SER B O   1 
ATOM 1353 C CB  . SER B 1 52  ? 274.432 294.119 382.664 1.00 31.83  ? 51  SER B CB  1 
ATOM 1354 O OG  . SER B 1 52  ? 275.204 294.527 381.554 1.00 31.83  ? 51  SER B OG  1 
ATOM 1355 N N   . VAL B 1 53  ? 276.395 291.723 383.812 1.00 35.27  ? 52  VAL B N   1 
ATOM 1356 C CA  . VAL B 1 53  ? 277.390 290.739 383.408 1.00 35.27  ? 52  VAL B CA  1 
ATOM 1357 C C   . VAL B 1 53  ? 276.721 289.679 382.540 1.00 35.27  ? 52  VAL B C   1 
ATOM 1358 O O   . VAL B 1 53  ? 275.674 289.134 382.902 1.00 35.27  ? 52  VAL B O   1 
ATOM 1359 C CB  . VAL B 1 53  ? 278.116 290.142 384.629 1.00 35.27  ? 52  VAL B CB  1 
ATOM 1360 C CG1 . VAL B 1 53  ? 277.156 289.757 385.685 1.00 35.27  ? 52  VAL B CG1 1 
ATOM 1361 C CG2 . VAL B 1 53  ? 278.928 288.932 384.235 1.00 35.27  ? 52  VAL B CG2 1 
ATOM 1362 N N   . SER B 1 54  ? 277.302 289.429 381.371 1.00 40.80  ? 53  SER B N   1 
ATOM 1363 C CA  . SER B 1 54  ? 276.698 288.601 380.342 1.00 40.80  ? 53  SER B CA  1 
ATOM 1364 C C   . SER B 1 54  ? 277.440 287.279 380.239 1.00 40.80  ? 53  SER B C   1 
ATOM 1365 O O   . SER B 1 54  ? 278.670 287.261 380.155 1.00 40.80  ? 53  SER B O   1 
ATOM 1366 C CB  . SER B 1 54  ? 276.717 289.318 378.995 1.00 40.80  ? 53  SER B CB  1 
ATOM 1367 O OG  . SER B 1 54  ? 275.925 290.487 379.030 1.00 40.80  ? 53  SER B OG  1 
ATOM 1368 N N   . GLN B 1 55  ? 276.691 286.183 380.246 1.00 47.85  ? 54  GLN B N   1 
ATOM 1369 C CA  . GLN B 1 55  ? 277.277 284.867 380.089 1.00 47.85  ? 54  GLN B CA  1 
ATOM 1370 C C   . GLN B 1 55  ? 277.778 284.673 378.660 1.00 47.85  ? 54  GLN B C   1 
ATOM 1371 O O   . GLN B 1 55  ? 277.269 285.301 377.731 1.00 47.85  ? 54  GLN B O   1 
ATOM 1372 C CB  . GLN B 1 55  ? 276.250 283.792 380.409 1.00 47.85  ? 54  GLN B CB  1 
ATOM 1373 C CG  . GLN B 1 55  ? 275.906 283.666 381.854 1.00 47.85  ? 54  GLN B CG  1 
ATOM 1374 C CD  . GLN B 1 55  ? 274.872 282.599 382.073 1.00 47.85  ? 54  GLN B CD  1 
ATOM 1375 O OE1 . GLN B 1 55  ? 274.325 282.047 381.121 1.00 47.85  ? 54  GLN B OE1 1 
ATOM 1376 N NE2 . GLN B 1 55  ? 274.608 282.283 383.326 1.00 47.85  ? 54  GLN B NE2 1 
ATOM 1377 N N   . PRO B 1 56  ? 278.781 283.821 378.456 1.00 50.10  ? 55  PRO B N   1 
ATOM 1378 C CA  . PRO B 1 56  ? 279.237 283.548 377.090 1.00 50.10  ? 55  PRO B CA  1 
ATOM 1379 C C   . PRO B 1 56  ? 278.226 282.704 376.332 1.00 50.10  ? 55  PRO B C   1 
ATOM 1380 O O   . PRO B 1 56  ? 277.885 281.592 376.738 1.00 50.10  ? 55  PRO B O   1 
ATOM 1381 C CB  . PRO B 1 56  ? 280.557 282.799 377.299 1.00 50.10  ? 55  PRO B CB  1 
ATOM 1382 C CG  . PRO B 1 56  ? 280.465 282.238 378.644 1.00 50.10  ? 55  PRO B CG  1 
ATOM 1383 C CD  . PRO B 1 56  ? 279.676 283.206 379.448 1.00 50.10  ? 55  PRO B CD  1 
ATOM 1384 N N   . SER B 1 57  ? 277.734 283.252 375.233 1.00 61.25  ? 56  SER B N   1 
ATOM 1385 C CA  . SER B 1 57  ? 276.778 282.563 374.382 1.00 61.25  ? 56  SER B CA  1 
ATOM 1386 C C   . SER B 1 57  ? 277.542 281.798 373.303 1.00 61.25  ? 56  SER B C   1 
ATOM 1387 O O   . SER B 1 57  ? 278.759 281.620 373.394 1.00 61.25  ? 56  SER B O   1 
ATOM 1388 C CB  . SER B 1 57  ? 275.779 283.566 373.800 1.00 61.25  ? 56  SER B CB  1 
ATOM 1389 O OG  . SER B 1 57  ? 276.425 284.481 372.932 1.00 61.25  ? 56  SER B OG  1 
ATOM 1390 N N   . ARG B 1 58  ? 276.842 281.343 372.269 1.00 68.35  ? 57  ARG B N   1 
ATOM 1391 C CA  . ARG B 1 58  ? 277.464 280.638 371.158 1.00 68.35  ? 57  ARG B CA  1 
ATOM 1392 C C   . ARG B 1 58  ? 278.106 281.569 370.134 1.00 68.35  ? 57  ARG B C   1 
ATOM 1393 O O   . ARG B 1 58  ? 278.446 281.115 369.038 1.00 68.35  ? 57  ARG B O   1 
ATOM 1394 C CB  . ARG B 1 58  ? 276.427 279.745 370.476 1.00 68.35  ? 57  ARG B CB  1 
ATOM 1395 C CG  . ARG B 1 58  ? 275.267 280.506 369.864 1.00 68.35  ? 57  ARG B CG  1 
ATOM 1396 C CD  . ARG B 1 58  ? 274.225 279.564 369.289 1.00 68.35  ? 57  ARG B CD  1 
ATOM 1397 N NE  . ARG B 1 58  ? 273.116 280.295 368.683 1.00 68.35  ? 57  ARG B NE  1 
ATOM 1398 C CZ  . ARG B 1 58  ? 272.083 279.720 368.076 1.00 68.35  ? 57  ARG B CZ  1 
ATOM 1399 N NH1 . ARG B 1 58  ? 272.012 278.398 367.990 1.00 68.35  ? 57  ARG B NH1 1 
ATOM 1400 N NH2 . ARG B 1 58  ? 271.122 280.467 367.552 1.00 68.35  ? 57  ARG B NH2 1 
ATOM 1401 N N   . ASN B 1 59  ? 278.279 282.850 370.456 1.00 64.65  ? 58  ASN B N   1 
ATOM 1402 C CA  . ASN B 1 59  ? 278.885 283.815 369.551 1.00 64.65  ? 58  ASN B CA  1 
ATOM 1403 C C   . ASN B 1 59  ? 280.050 284.568 370.179 1.00 64.65  ? 58  ASN B C   1 
ATOM 1404 O O   . ASN B 1 59  ? 281.047 284.837 369.504 1.00 64.65  ? 58  ASN B O   1 
ATOM 1405 C CB  . ASN B 1 59  ? 277.816 284.813 369.077 1.00 64.65  ? 58  ASN B CB  1 
ATOM 1406 C CG  . ASN B 1 59  ? 278.232 285.577 367.832 1.00 64.65  ? 58  ASN B CG  1 
ATOM 1407 O OD1 . ASN B 1 59  ? 279.296 285.339 367.261 1.00 64.65  ? 58  ASN B OD1 1 
ATOM 1408 N ND2 . ASN B 1 59  ? 277.387 286.507 367.406 1.00 64.65  ? 58  ASN B ND2 1 
ATOM 1409 N N   . ARG B 1 60  ? 279.962 284.909 371.465 1.00 54.62  ? 59  ARG B N   1 
ATOM 1410 C CA  . ARG B 1 60  ? 280.892 285.873 372.039 1.00 54.62  ? 59  ARG B CA  1 
ATOM 1411 C C   . ARG B 1 60  ? 282.036 285.220 372.807 1.00 54.62  ? 59  ARG B C   1 
ATOM 1412 O O   . ARG B 1 60  ? 283.143 285.773 372.834 1.00 54.62  ? 59  ARG B O   1 
ATOM 1413 C CB  . ARG B 1 60  ? 280.130 286.838 372.948 1.00 54.62  ? 59  ARG B CB  1 
ATOM 1414 C CG  . ARG B 1 60  ? 280.899 288.087 373.344 1.00 54.62  ? 59  ARG B CG  1 
ATOM 1415 C CD  . ARG B 1 60  ? 280.061 288.969 374.242 1.00 54.62  ? 59  ARG B CD  1 
ATOM 1416 N NE  . ARG B 1 60  ? 279.857 288.340 375.538 1.00 54.62  ? 59  ARG B NE  1 
ATOM 1417 C CZ  . ARG B 1 60  ? 278.696 287.863 375.962 1.00 54.62  ? 59  ARG B CZ  1 
ATOM 1418 N NH1 . ARG B 1 60  ? 277.624 287.924 375.186 1.00 54.62  ? 59  ARG B NH1 1 
ATOM 1419 N NH2 . ARG B 1 60  ? 278.617 287.309 377.155 1.00 54.62  ? 59  ARG B NH2 1 
ATOM 1420 N N   . LYS B 1 61  ? 281.756 284.108 373.504 1.00 53.70  ? 60  LYS B N   1 
ATOM 1421 C CA  . LYS B 1 61  ? 282.711 283.177 374.116 1.00 53.70  ? 60  LYS B CA  1 
ATOM 1422 C C   . LYS B 1 61  ? 283.396 283.754 375.365 1.00 53.70  ? 60  LYS B C   1 
ATOM 1423 O O   . LYS B 1 61  ? 284.092 283.034 376.088 1.00 53.70  ? 60  LYS B O   1 
ATOM 1424 C CB  . LYS B 1 61  ? 283.735 282.708 373.057 1.00 53.70  ? 60  LYS B CB  1 
ATOM 1425 C CG  . LYS B 1 61  ? 284.589 281.488 373.386 1.00 53.70  ? 60  LYS B CG  1 
ATOM 1426 C CD  . LYS B 1 61  ? 285.475 281.106 372.216 1.00 53.70  ? 60  LYS B CD  1 
ATOM 1427 C CE  . LYS B 1 61  ? 286.616 282.093 372.052 1.00 53.70  ? 60  LYS B CE  1 
ATOM 1428 N NZ  . LYS B 1 61  ? 287.568 281.666 370.991 1.00 53.70  ? 60  LYS B NZ  1 
ATOM 1429 N N   . ASN B 1 62  ? 283.151 285.019 375.692 1.00 47.43  ? 61  ASN B N   1 
ATOM 1430 C CA  . ASN B 1 62  ? 283.774 285.648 376.846 1.00 47.43  ? 61  ASN B CA  1 
ATOM 1431 C C   . ASN B 1 62  ? 282.726 286.226 377.786 1.00 47.43  ? 61  ASN B C   1 
ATOM 1432 O O   . ASN B 1 62  ? 281.668 286.684 377.357 1.00 47.43  ? 61  ASN B O   1 
ATOM 1433 C CB  . ASN B 1 62  ? 284.725 286.758 376.418 1.00 47.43  ? 61  ASN B CB  1 
ATOM 1434 C CG  . ASN B 1 62  ? 285.883 286.244 375.611 1.00 47.43  ? 61  ASN B CG  1 
ATOM 1435 O OD1 . ASN B 1 62  ? 286.045 286.593 374.445 1.00 47.43  ? 61  ASN B OD1 1 
ATOM 1436 N ND2 . ASN B 1 62  ? 286.694 285.397 376.221 1.00 47.43  ? 61  ASN B ND2 1 
ATOM 1437 N N   . TYR B 1 63  ? 283.035 286.184 379.078 1.00 40.30  ? 62  TYR B N   1 
ATOM 1438 C CA  . TYR B 1 63  ? 282.264 286.908 380.073 1.00 40.30  ? 62  TYR B CA  1 
ATOM 1439 C C   . TYR B 1 63  ? 282.505 288.398 379.917 1.00 40.30  ? 62  TYR B C   1 
ATOM 1440 O O   . TYR B 1 63  ? 283.582 288.828 379.506 1.00 40.30  ? 62  TYR B O   1 
ATOM 1441 C CB  . TYR B 1 63  ? 282.661 286.459 381.471 1.00 40.30  ? 62  TYR B CB  1 
ATOM 1442 C CG  . TYR B 1 63  ? 282.186 285.085 381.846 1.00 40.30  ? 62  TYR B CG  1 
ATOM 1443 C CD1 . TYR B 1 63  ? 282.906 283.960 381.492 1.00 40.30  ? 62  TYR B CD1 1 
ATOM 1444 C CD2 . TYR B 1 63  ? 280.992 284.912 382.526 1.00 40.30  ? 62  TYR B CD2 1 
ATOM 1445 C CE1 . TYR B 1 63  ? 282.468 282.704 381.824 1.00 40.30  ? 62  TYR B CE1 1 
ATOM 1446 C CE2 . TYR B 1 63  ? 280.553 283.661 382.877 1.00 40.30  ? 62  TYR B CE2 1 
ATOM 1447 C CZ  . TYR B 1 63  ? 281.292 282.560 382.519 1.00 40.30  ? 62  TYR B CZ  1 
ATOM 1448 O OH  . TYR B 1 63  ? 280.855 281.304 382.852 1.00 40.30  ? 62  TYR B OH  1 
ATOM 1449 N N   . LYS B 1 64  ? 281.494 289.202 380.240 1.00 36.62  ? 63  LYS B N   1 
ATOM 1450 C CA  . LYS B 1 64  ? 281.597 290.632 379.965 1.00 36.62  ? 63  LYS B CA  1 
ATOM 1451 C C   . LYS B 1 64  ? 280.823 291.415 381.021 1.00 36.62  ? 63  LYS B C   1 
ATOM 1452 O O   . LYS B 1 64  ? 279.599 291.525 380.938 1.00 36.62  ? 63  LYS B O   1 
ATOM 1453 C CB  . LYS B 1 64  ? 281.093 290.943 378.567 1.00 36.62  ? 63  LYS B CB  1 
ATOM 1454 C CG  . LYS B 1 64  ? 281.274 292.385 378.182 1.00 36.62  ? 63  LYS B CG  1 
ATOM 1455 C CD  . LYS B 1 64  ? 280.859 292.646 376.753 1.00 36.62  ? 63  LYS B CD  1 
ATOM 1456 C CE  . LYS B 1 64  ? 279.349 292.690 376.619 1.00 36.62  ? 63  LYS B CE  1 
ATOM 1457 N NZ  . LYS B 1 64  ? 278.928 293.068 375.243 1.00 36.62  ? 63  LYS B NZ  1 
ATOM 1458 N N   . VAL B 1 65  ? 281.536 291.961 381.987 1.00 31.61  ? 64  VAL B N   1 
ATOM 1459 C CA  . VAL B 1 65  ? 280.950 292.882 382.950 1.00 31.61  ? 64  VAL B CA  1 
ATOM 1460 C C   . VAL B 1 65  ? 280.934 294.272 382.336 1.00 31.61  ? 64  VAL B C   1 
ATOM 1461 O O   . VAL B 1 65  ? 281.883 294.671 381.658 1.00 31.61  ? 64  VAL B O   1 
ATOM 1462 C CB  . VAL B 1 65  ? 281.745 292.846 384.264 1.00 31.61  ? 64  VAL B CB  1 
ATOM 1463 C CG1 . VAL B 1 65  ? 281.125 293.741 385.309 1.00 31.61  ? 64  VAL B CG1 1 
ATOM 1464 C CG2 . VAL B 1 65  ? 281.837 291.429 384.765 1.00 31.61  ? 64  VAL B CG2 1 
ATOM 1465 N N   . GLN B 1 66  ? 279.845 295.012 382.537 1.00 28.65  ? 65  GLN B N   1 
ATOM 1466 C CA  . GLN B 1 66  ? 279.692 296.304 381.879 1.00 28.65  ? 65  GLN B CA  1 
ATOM 1467 C C   . GLN B 1 66  ? 278.945 297.263 382.789 1.00 28.65  ? 65  GLN B C   1 
ATOM 1468 O O   . GLN B 1 66  ? 277.792 297.010 383.134 1.00 28.65  ? 65  GLN B O   1 
ATOM 1469 C CB  . GLN B 1 66  ? 278.968 296.139 380.551 1.00 28.65  ? 65  GLN B CB  1 
ATOM 1470 C CG  . GLN B 1 66  ? 278.835 297.414 379.781 1.00 28.65  ? 65  GLN B CG  1 
ATOM 1471 C CD  . GLN B 1 66  ? 278.421 297.171 378.360 1.00 28.65  ? 65  GLN B CD  1 
ATOM 1472 O OE1 . GLN B 1 66  ? 278.204 296.034 377.953 1.00 28.65  ? 65  GLN B OE1 1 
ATOM 1473 N NE2 . GLN B 1 66  ? 278.330 298.238 377.581 1.00 28.65  ? 65  GLN B NE2 1 
ATOM 1474 N N   . VAL B 1 67  ? 279.597 298.366 383.153 1.00 27.62  ? 66  VAL B N   1 
ATOM 1475 C CA  . VAL B 1 67  ? 279.081 299.338 384.112 1.00 27.62  ? 66  VAL B CA  1 
ATOM 1476 C C   . VAL B 1 67  ? 278.947 300.685 383.417 1.00 27.62  ? 66  VAL B C   1 
ATOM 1477 O O   . VAL B 1 67  ? 279.885 301.133 382.754 1.00 27.62  ? 66  VAL B O   1 
ATOM 1478 C CB  . VAL B 1 67  ? 280.011 299.449 385.332 1.00 27.62  ? 66  VAL B CB  1 
ATOM 1479 C CG1 . VAL B 1 67  ? 279.567 300.536 386.279 1.00 27.62  ? 66  VAL B CG1 1 
ATOM 1480 C CG2 . VAL B 1 67  ? 280.073 298.132 386.037 1.00 27.62  ? 66  VAL B CG2 1 
ATOM 1481 N N   . LYS B 1 68  ? 277.792 301.328 383.568 1.00 28.98  ? 67  LYS B N   1 
ATOM 1482 C CA  . LYS B 1 68  ? 277.551 302.637 382.986 1.00 28.98  ? 67  LYS B CA  1 
ATOM 1483 C C   . LYS B 1 68  ? 277.125 303.629 384.060 1.00 28.98  ? 67  LYS B C   1 
ATOM 1484 O O   . LYS B 1 68  ? 276.517 303.259 385.062 1.00 28.98  ? 67  LYS B O   1 
ATOM 1485 C CB  . LYS B 1 68  ? 276.497 302.569 381.896 1.00 28.98  ? 67  LYS B CB  1 
ATOM 1486 C CG  . LYS B 1 68  ? 276.955 301.843 380.662 1.00 28.98  ? 67  LYS B CG  1 
ATOM 1487 C CD  . LYS B 1 68  ? 275.889 301.892 379.594 1.00 28.98  ? 67  LYS B CD  1 
ATOM 1488 C CE  . LYS B 1 68  ? 276.315 301.108 378.373 1.00 28.98  ? 67  LYS B CE  1 
ATOM 1489 N NZ  . LYS B 1 68  ? 275.296 301.153 377.298 1.00 28.98  ? 67  LYS B NZ  1 
ATOM 1490 N N   . ILE B 1 69  ? 277.460 304.897 383.840 1.00 28.47  ? 68  ILE B N   1 
ATOM 1491 C CA  . ILE B 1 69  ? 277.227 305.985 384.785 1.00 28.47  ? 68  ILE B CA  1 
ATOM 1492 C C   . ILE B 1 69  ? 276.752 307.195 384.001 1.00 28.47  ? 68  ILE B C   1 
ATOM 1493 O O   . ILE B 1 69  ? 277.402 307.602 383.038 1.00 28.47  ? 68  ILE B O   1 
ATOM 1494 C CB  . ILE B 1 69  ? 278.501 306.333 385.580 1.00 28.47  ? 68  ILE B CB  1 
ATOM 1495 C CG1 . ILE B 1 69  ? 278.844 305.244 386.587 1.00 28.47  ? 68  ILE B CG1 1 
ATOM 1496 C CG2 . ILE B 1 69  ? 278.370 307.656 386.287 1.00 28.47  ? 68  ILE B CG2 1 
ATOM 1497 C CD1 . ILE B 1 69  ? 280.182 305.426 387.203 1.00 28.47  ? 68  ILE B CD1 1 
ATOM 1498 N N   . GLN B 1 70  ? 275.618 307.764 384.397 1.00 33.02  ? 69  GLN B N   1 
ATOM 1499 C CA  . GLN B 1 70  ? 275.033 308.910 383.712 1.00 33.02  ? 69  GLN B CA  1 
ATOM 1500 C C   . GLN B 1 70  ? 274.734 310.003 384.724 1.00 33.02  ? 69  GLN B C   1 
ATOM 1501 O O   . GLN B 1 70  ? 273.964 309.786 385.661 1.00 33.02  ? 69  GLN B O   1 
ATOM 1502 C CB  . GLN B 1 70  ? 273.765 308.498 382.974 1.00 33.02  ? 69  GLN B CB  1 
ATOM 1503 C CG  . GLN B 1 70  ? 273.115 309.596 382.204 1.00 33.02  ? 69  GLN B CG  1 
ATOM 1504 C CD  . GLN B 1 70  ? 271.906 309.114 381.451 1.00 33.02  ? 69  GLN B CD  1 
ATOM 1505 O OE1 . GLN B 1 70  ? 271.551 307.943 381.513 1.00 33.02  ? 69  GLN B OE1 1 
ATOM 1506 N NE2 . GLN B 1 70  ? 271.257 310.021 380.738 1.00 33.02  ? 69  GLN B NE2 1 
ATOM 1507 N N   . ASN B 1 71  ? 275.346 311.167 384.546 1.00 34.09  ? 70  ASN B N   1 
ATOM 1508 C CA  . ASN B 1 71  ? 275.149 312.297 385.453 1.00 34.09  ? 70  ASN B CA  1 
ATOM 1509 C C   . ASN B 1 71  ? 274.655 313.500 384.677 1.00 34.09  ? 70  ASN B C   1 
ATOM 1510 O O   . ASN B 1 71  ? 275.439 314.109 383.926 1.00 34.09  ? 70  ASN B O   1 
ATOM 1511 C CB  . ASN B 1 71  ? 276.442 312.658 386.179 1.00 34.09  ? 70  ASN B CB  1 
ATOM 1512 C CG  . ASN B 1 71  ? 276.977 311.530 387.009 1.00 34.09  ? 70  ASN B CG  1 
ATOM 1513 O OD1 . ASN B 1 71  ? 278.067 311.033 386.765 1.00 34.09  ? 70  ASN B OD1 1 
ATOM 1514 N ND2 . ASN B 1 71  ? 276.211 311.112 387.997 1.00 34.09  ? 70  ASN B ND2 1 
ATOM 1515 N N   . PRO B 1 72  ? 273.396 313.889 384.806 1.00 36.15  ? 71  PRO B N   1 
ATOM 1516 C CA  . PRO B 1 72  ? 272.928 315.117 384.168 1.00 36.15  ? 71  PRO B CA  1 
ATOM 1517 C C   . PRO B 1 72  ? 273.059 316.308 385.101 1.00 36.15  ? 71  PRO B C   1 
ATOM 1518 O O   . PRO B 1 72  ? 273.080 316.178 386.325 1.00 36.15  ? 71  PRO B O   1 
ATOM 1519 C CB  . PRO B 1 72  ? 271.455 314.810 383.894 1.00 36.15  ? 71  PRO B CB  1 
ATOM 1520 C CG  . PRO B 1 72  ? 271.081 313.925 385.000 1.00 36.15  ? 71  PRO B CG  1 
ATOM 1521 C CD  . PRO B 1 72  ? 272.278 313.082 385.309 1.00 36.15  ? 71  PRO B CD  1 
ATOM 1522 N N   . THR B 1 73  ? 273.153 317.487 384.496 1.00 40.63  ? 72  THR B N   1 
ATOM 1523 C CA  . THR B 1 73  ? 273.093 318.735 385.241 1.00 40.63  ? 72  THR B CA  1 
ATOM 1524 C C   . THR B 1 73  ? 271.901 319.543 384.756 1.00 40.63  ? 72  THR B C   1 
ATOM 1525 O O   . THR B 1 73  ? 271.472 319.414 383.609 1.00 40.63  ? 72  THR B O   1 
ATOM 1526 C CB  . THR B 1 73  ? 274.369 319.552 385.090 1.00 40.63  ? 72  THR B CB  1 
ATOM 1527 O OG1 . THR B 1 73  ? 274.542 319.900 383.718 1.00 40.63  ? 72  THR B OG1 1 
ATOM 1528 C CG2 . THR B 1 73  ? 275.564 318.752 385.551 1.00 40.63  ? 72  THR B CG2 1 
ATOM 1529 N N   . ALA B 1 74  ? 271.371 320.382 385.638 1.00 50.54  ? 73  ALA B N   1 
ATOM 1530 C CA  . ALA B 1 74  ? 270.110 321.062 385.401 1.00 50.54  ? 73  ALA B CA  1 
ATOM 1531 C C   . ALA B 1 74  ? 270.232 322.557 385.645 1.00 50.54  ? 73  ALA B C   1 
ATOM 1532 O O   . ALA B 1 74  ? 270.934 322.997 386.559 1.00 50.54  ? 73  ALA B O   1 
ATOM 1533 C CB  . ALA B 1 74  ? 269.020 320.508 386.302 1.00 50.54  ? 73  ALA B CB  1 
ATOM 1534 N N   . CYS B 1 75  ? 269.510 323.331 384.834 1.00 62.34  ? 74  CYS B N   1 
ATOM 1535 C CA  . CYS B 1 75  ? 269.385 324.766 385.043 1.00 62.34  ? 74  CYS B CA  1 
ATOM 1536 C C   . CYS B 1 75  ? 268.154 325.264 384.303 1.00 62.34  ? 74  CYS B C   1 
ATOM 1537 O O   . CYS B 1 75  ? 267.802 324.758 383.236 1.00 62.34  ? 74  CYS B O   1 
ATOM 1538 C CB  . CYS B 1 75  ? 270.631 325.531 384.576 1.00 62.34  ? 74  CYS B CB  1 
ATOM 1539 S SG  . CYS B 1 75  ? 270.952 325.485 382.805 1.00 62.34  ? 74  CYS B SG  1 
ATOM 1540 N N   . THR B 1 76  ? 267.515 326.275 384.884 1.00 74.60  ? 75  THR B N   1 
ATOM 1541 C CA  . THR B 1 76  ? 266.336 326.907 384.312 1.00 74.60  ? 75  THR B CA  1 
ATOM 1542 C C   . THR B 1 76  ? 266.738 328.142 383.514 1.00 74.60  ? 75  THR B C   1 
ATOM 1543 O O   . THR B 1 76  ? 267.728 328.809 383.833 1.00 74.60  ? 75  THR B O   1 
ATOM 1544 C CB  . THR B 1 76  ? 265.321 327.271 385.407 1.00 74.60  ? 75  THR B CB  1 
ATOM 1545 O OG1 . THR B 1 76  ? 264.176 327.897 384.819 1.00 74.60  ? 75  THR B OG1 1 
ATOM 1546 C CG2 . THR B 1 76  ? 265.928 328.180 386.466 1.00 74.60  ? 75  THR B CG2 1 
ATOM 1547 N N   . ALA B 1 77  ? 265.984 328.425 382.456 1.00 83.66  ? 76  ALA B N   1 
ATOM 1548 C CA  . ALA B 1 77  ? 266.300 329.509 381.540 1.00 83.66  ? 76  ALA B CA  1 
ATOM 1549 C C   . ALA B 1 77  ? 265.301 330.652 381.701 1.00 83.66  ? 76  ALA B C   1 
ATOM 1550 O O   . ALA B 1 77  ? 264.417 330.628 382.559 1.00 83.66  ? 76  ALA B O   1 
ATOM 1551 C CB  . ALA B 1 77  ? 266.324 328.995 380.100 1.00 83.66  ? 76  ALA B CB  1 
ATOM 1552 N N   . ASN B 1 78  ? 265.452 331.669 380.855 1.00 88.62  ? 77  ASN B N   1 
ATOM 1553 C CA  . ASN B 1 78  ? 264.576 332.831 380.905 1.00 88.62  ? 77  ASN B CA  1 
ATOM 1554 C C   . ASN B 1 78  ? 263.195 332.477 380.365 1.00 88.62  ? 77  ASN B C   1 
ATOM 1555 O O   . ASN B 1 78  ? 263.071 331.850 379.309 1.00 88.62  ? 77  ASN B O   1 
ATOM 1556 C CB  . ASN B 1 78  ? 265.178 333.982 380.101 1.00 88.62  ? 77  ASN B CB  1 
ATOM 1557 C CG  . ASN B 1 78  ? 266.437 334.544 380.735 1.00 88.62  ? 77  ASN B CG  1 
ATOM 1558 O OD1 . ASN B 1 78  ? 266.517 334.698 381.953 1.00 88.62  ? 77  ASN B OD1 1 
ATOM 1559 N ND2 . ASN B 1 78  ? 267.428 334.858 379.907 1.00 88.62  ? 77  ASN B ND2 1 
ATOM 1560 N N   . GLY B 1 79  ? 262.156 332.875 381.095 1.00 86.70  ? 78  GLY B N   1 
ATOM 1561 C CA  . GLY B 1 79  ? 260.802 332.562 380.686 1.00 86.70  ? 78  GLY B CA  1 
ATOM 1562 C C   . GLY B 1 79  ? 260.389 331.127 380.910 1.00 86.70  ? 78  GLY B C   1 
ATOM 1563 O O   . GLY B 1 79  ? 259.377 330.691 380.354 1.00 86.70  ? 78  GLY B O   1 
ATOM 1564 N N   . SER B 1 80  ? 261.144 330.377 381.713 1.00 84.59  ? 79  SER B N   1 
ATOM 1565 C CA  . SER B 1 80  ? 260.865 328.975 381.992 1.00 84.59  ? 79  SER B CA  1 
ATOM 1566 C C   . SER B 1 80  ? 260.822 328.758 383.498 1.00 84.59  ? 79  SER B C   1 
ATOM 1567 O O   . SER B 1 80  ? 261.559 329.406 384.246 1.00 84.59  ? 79  SER B O   1 
ATOM 1568 C CB  . SER B 1 80  ? 261.920 328.068 381.361 1.00 84.59  ? 79  SER B CB  1 
ATOM 1569 O OG  . SER B 1 80  ? 261.657 326.708 381.647 1.00 84.59  ? 79  SER B OG  1 
ATOM 1570 N N   . CYS B 1 81  ? 259.954 327.847 383.938 1.00 81.12  ? 80  CYS B N   1 
ATOM 1571 C CA  . CYS B 1 81  ? 259.740 327.624 385.365 1.00 81.12  ? 80  CYS B CA  1 
ATOM 1572 C C   . CYS B 1 81  ? 260.500 326.406 385.878 1.00 81.12  ? 80  CYS B C   1 
ATOM 1573 O O   . CYS B 1 81  ? 261.318 326.518 386.797 1.00 81.12  ? 80  CYS B O   1 
ATOM 1574 C CB  . CYS B 1 81  ? 258.243 327.469 385.654 1.00 81.12  ? 80  CYS B CB  1 
ATOM 1575 S SG  . CYS B 1 81  ? 257.269 328.970 385.438 1.00 81.12  ? 80  CYS B SG  1 
ATOM 1576 N N   . ASP B 1 82  ? 260.243 325.266 385.313 1.00 73.12  ? 81  ASP B N   1 
ATOM 1577 C CA  . ASP B 1 82  ? 260.860 324.049 385.811 1.00 73.12  ? 81  ASP B CA  1 
ATOM 1578 C C   . ASP B 1 82  ? 262.245 323.855 385.203 1.00 73.12  ? 81  ASP B C   1 
ATOM 1579 O O   . ASP B 1 82  ? 262.489 324.260 384.062 1.00 73.12  ? 81  ASP B O   1 
ATOM 1580 C CB  . ASP B 1 82  ? 259.981 322.846 385.493 1.00 73.12  ? 81  ASP B CB  1 
ATOM 1581 C CG  . ASP B 1 82  ? 258.729 322.811 386.337 1.00 73.12  ? 81  ASP B CG  1 
ATOM 1582 O OD1 . ASP B 1 82  ? 258.766 323.334 387.470 1.00 73.12  ? 81  ASP B OD1 1 
ATOM 1583 O OD2 . ASP B 1 82  ? 257.712 322.257 385.874 1.00 73.12  ? 81  ASP B OD2 1 
ATOM 1584 N N   . PRO B 1 83  ? 263.177 323.259 385.947 1.00 62.65  ? 82  PRO B N   1 
ATOM 1585 C CA  . PRO B 1 83  ? 264.519 323.041 385.399 1.00 62.65  ? 82  PRO B CA  1 
ATOM 1586 C C   . PRO B 1 83  ? 264.526 321.948 384.345 1.00 62.65  ? 82  PRO B C   1 
ATOM 1587 O O   . PRO B 1 83  ? 263.862 320.919 384.481 1.00 62.65  ? 82  PRO B O   1 
ATOM 1588 C CB  . PRO B 1 83  ? 265.341 322.638 386.626 1.00 62.65  ? 82  PRO B CB  1 
ATOM 1589 C CG  . PRO B 1 83  ? 264.352 322.079 387.570 1.00 62.65  ? 82  PRO B CG  1 
ATOM 1590 C CD  . PRO B 1 83  ? 263.100 322.867 387.366 1.00 62.65  ? 82  PRO B CD  1 
ATOM 1591 N N   . SER B 1 84  ? 265.279 322.187 383.283 1.00 52.22  ? 83  SER B N   1 
ATOM 1592 C CA  . SER B 1 84  ? 265.470 321.235 382.206 1.00 52.22  ? 83  SER B CA  1 
ATOM 1593 C C   . SER B 1 84  ? 266.849 320.607 382.343 1.00 52.22  ? 83  SER B C   1 
ATOM 1594 O O   . SER B 1 84  ? 267.569 320.849 383.309 1.00 52.22  ? 83  SER B O   1 
ATOM 1595 C CB  . SER B 1 84  ? 265.299 321.915 380.849 1.00 52.22  ? 83  SER B CB  1 
ATOM 1596 O OG  . SER B 1 84  ? 266.334 322.851 380.618 1.00 52.22  ? 83  SER B OG  1 
ATOM 1597 N N   . VAL B 1 85  ? 267.221 319.790 381.364 1.00 43.50  ? 84  VAL B N   1 
ATOM 1598 C CA  . VAL B 1 85  ? 268.486 319.066 381.381 1.00 43.50  ? 84  VAL B CA  1 
ATOM 1599 C C   . VAL B 1 85  ? 269.346 319.569 380.234 1.00 43.50  ? 84  VAL B C   1 
ATOM 1600 O O   . VAL B 1 85  ? 268.936 319.505 379.071 1.00 43.50  ? 84  VAL B O   1 
ATOM 1601 C CB  . VAL B 1 85  ? 268.267 317.550 381.265 1.00 43.50  ? 84  VAL B CB  1 
ATOM 1602 C CG1 . VAL B 1 85  ? 269.576 316.849 381.319 1.00 43.50  ? 84  VAL B CG1 1 
ATOM 1603 C CG2 . VAL B 1 85  ? 267.377 317.061 382.357 1.00 43.50  ? 84  VAL B CG2 1 
ATOM 1604 N N   . THR B 1 86  ? 270.543 320.048 380.556 1.00 41.08  ? 85  THR B N   1 
ATOM 1605 C CA  . THR B 1 86  ? 271.425 320.667 379.574 1.00 41.08  ? 85  THR B CA  1 
ATOM 1606 C C   . THR B 1 86  ? 272.640 319.831 379.206 1.00 41.08  ? 85  THR B C   1 
ATOM 1607 O O   . THR B 1 86  ? 273.048 319.838 378.046 1.00 41.08  ? 85  THR B O   1 
ATOM 1608 C CB  . THR B 1 86  ? 271.884 322.034 380.080 1.00 41.08  ? 85  THR B CB  1 
ATOM 1609 O OG1 . THR B 1 86  ? 272.467 321.896 381.378 1.00 41.08  ? 85  THR B OG1 1 
ATOM 1610 C CG2 . THR B 1 86  ? 270.711 322.964 380.166 1.00 41.08  ? 85  THR B CG2 1 
ATOM 1611 N N   . ARG B 1 87  ? 273.243 319.111 380.147 1.00 36.64  ? 86  ARG B N   1 
ATOM 1612 C CA  . ARG B 1 87  ? 274.457 318.366 379.862 1.00 36.64  ? 86  ARG B CA  1 
ATOM 1613 C C   . ARG B 1 87  ? 274.340 316.944 380.378 1.00 36.64  ? 86  ARG B C   1 
ATOM 1614 O O   . ARG B 1 87  ? 273.506 316.634 381.228 1.00 36.64  ? 86  ARG B O   1 
ATOM 1615 C CB  . ARG B 1 87  ? 275.681 319.035 380.476 1.00 36.64  ? 86  ARG B CB  1 
ATOM 1616 C CG  . ARG B 1 87  ? 276.013 320.373 379.885 1.00 36.64  ? 86  ARG B CG  1 
ATOM 1617 C CD  . ARG B 1 87  ? 277.364 320.795 380.334 1.00 36.64  ? 86  ARG B CD  1 
ATOM 1618 N NE  . ARG B 1 87  ? 277.408 320.972 381.773 1.00 36.64  ? 86  ARG B NE  1 
ATOM 1619 C CZ  . ARG B 1 87  ? 277.171 322.124 382.384 1.00 36.64  ? 86  ARG B CZ  1 
ATOM 1620 N NH1 . ARG B 1 87  ? 276.878 323.199 381.674 1.00 36.64  ? 86  ARG B NH1 1 
ATOM 1621 N NH2 . ARG B 1 87  ? 277.236 322.204 383.700 1.00 36.64  ? 86  ARG B NH2 1 
ATOM 1622 N N   . GLN B 1 88  ? 275.198 316.082 379.844 1.00 34.28  ? 87  GLN B N   1 
ATOM 1623 C CA  . GLN B 1 88  ? 275.246 314.669 380.194 1.00 34.28  ? 87  GLN B CA  1 
ATOM 1624 C C   . GLN B 1 88  ? 276.709 314.273 380.281 1.00 34.28  ? 87  GLN B C   1 
ATOM 1625 O O   . GLN B 1 88  ? 277.442 314.415 379.301 1.00 34.28  ? 87  GLN B O   1 
ATOM 1626 C CB  . GLN B 1 88  ? 274.546 313.813 379.138 1.00 34.28  ? 87  GLN B CB  1 
ATOM 1627 C CG  . GLN B 1 88  ? 273.058 314.008 378.953 1.00 34.28  ? 87  GLN B CG  1 
ATOM 1628 C CD  . GLN B 1 88  ? 272.257 313.471 380.103 1.00 34.28  ? 87  GLN B CD  1 
ATOM 1629 O OE1 . GLN B 1 88  ? 272.649 312.508 380.745 1.00 34.28  ? 87  GLN B OE1 1 
ATOM 1630 N NE2 . GLN B 1 88  ? 271.101 314.054 380.334 1.00 34.28  ? 87  GLN B NE2 1 
ATOM 1631 N N   . ALA B 1 89  ? 277.138 313.771 381.431 1.00 31.35  ? 88  ALA B N   1 
ATOM 1632 C CA  . ALA B 1 89  ? 278.518 313.326 381.614 1.00 31.35  ? 88  ALA B CA  1 
ATOM 1633 C C   . ALA B 1 89  ? 278.513 311.816 381.799 1.00 31.35  ? 88  ALA B C   1 
ATOM 1634 O O   . ALA B 1 89  ? 278.274 311.328 382.903 1.00 31.35  ? 88  ALA B O   1 
ATOM 1635 C CB  . ALA B 1 89  ? 279.162 314.028 382.802 1.00 31.35  ? 88  ALA B CB  1 
ATOM 1636 N N   . TYR B 1 90  ? 278.801 311.078 380.735 1.00 29.18  ? 89  TYR B N   1 
ATOM 1637 C CA  . TYR B 1 90  ? 278.681 309.633 380.762 1.00 29.18  ? 89  TYR B CA  1 
ATOM 1638 C C   . TYR B 1 90  ? 279.957 308.975 381.282 1.00 29.18  ? 89  TYR B C   1 
ATOM 1639 O O   . TYR B 1 90  ? 280.968 309.624 381.538 1.00 29.18  ? 89  TYR B O   1 
ATOM 1640 C CB  . TYR B 1 90  ? 278.356 309.100 379.374 1.00 29.18  ? 89  TYR B CB  1 
ATOM 1641 C CG  . TYR B 1 90  ? 277.076 309.642 378.810 1.00 29.18  ? 89  TYR B CG  1 
ATOM 1642 C CD1 . TYR B 1 90  ? 275.852 309.203 379.279 1.00 29.18  ? 89  TYR B CD1 1 
ATOM 1643 C CD2 . TYR B 1 90  ? 277.092 310.562 377.781 1.00 29.18  ? 89  TYR B CD2 1 
ATOM 1644 C CE1 . TYR B 1 90  ? 274.679 309.693 378.764 1.00 29.18  ? 89  TYR B CE1 1 
ATOM 1645 C CE2 . TYR B 1 90  ? 275.926 311.052 377.256 1.00 29.18  ? 89  TYR B CE2 1 
ATOM 1646 C CZ  . TYR B 1 90  ? 274.722 310.608 377.745 1.00 29.18  ? 89  TYR B CZ  1 
ATOM 1647 O OH  . TYR B 1 90  ? 273.554 311.100 377.223 1.00 29.18  ? 89  TYR B OH  1 
ATOM 1648 N N   . ALA B 1 91  ? 279.896 307.653 381.424 1.00 28.30  ? 90  ALA B N   1 
ATOM 1649 C CA  . ALA B 1 91  ? 281.029 306.788 381.726 1.00 28.30  ? 90  ALA B CA  1 
ATOM 1650 C C   . ALA B 1 91  ? 280.630 305.377 381.336 1.00 28.30  ? 90  ALA B C   1 
ATOM 1651 O O   . ALA B 1 91  ? 279.461 305.007 381.436 1.00 28.30  ? 90  ALA B O   1 
ATOM 1652 C CB  . ALA B 1 91  ? 281.421 306.838 383.200 1.00 28.30  ? 90  ALA B CB  1 
ATOM 1653 N N   . ASP B 1 92  ? 281.604 304.590 380.890 1.00 30.15  ? 91  ASP B N   1 
ATOM 1654 C CA  . ASP B 1 92  ? 281.297 303.309 380.260 1.00 30.15  ? 91  ASP B CA  1 
ATOM 1655 C C   . ASP B 1 92  ? 282.496 302.379 380.413 1.00 30.15  ? 91  ASP B C   1 
ATOM 1656 O O   . ASP B 1 92  ? 283.456 302.482 379.650 1.00 30.15  ? 91  ASP B O   1 
ATOM 1657 C CB  . ASP B 1 92  ? 280.945 303.514 378.798 1.00 30.15  ? 91  ASP B CB  1 
ATOM 1658 C CG  . ASP B 1 92  ? 280.656 302.220 378.088 1.00 30.15  ? 91  ASP B CG  1 
ATOM 1659 O OD1 . ASP B 1 92  ? 279.593 301.623 378.344 1.00 30.15  ? 91  ASP B OD1 1 
ATOM 1660 O OD2 . ASP B 1 92  ? 281.491 301.800 377.262 1.00 30.15  ? 91  ASP B OD2 1 
ATOM 1661 N N   . VAL B 1 93  ? 282.422 301.459 381.369 1.00 28.74  ? 92  VAL B N   1 
ATOM 1662 C CA  . VAL B 1 93  ? 283.505 300.532 381.663 1.00 28.74  ? 92  VAL B CA  1 
ATOM 1663 C C   . VAL B 1 93  ? 283.069 299.140 381.242 1.00 28.74  ? 92  VAL B C   1 
ATOM 1664 O O   . VAL B 1 93  ? 282.022 298.662 381.683 1.00 28.74  ? 92  VAL B O   1 
ATOM 1665 C CB  . VAL B 1 93  ? 283.851 300.541 383.157 1.00 28.74  ? 92  VAL B CB  1 
ATOM 1666 C CG1 . VAL B 1 93  ? 285.086 299.717 383.405 1.00 28.74  ? 92  VAL B CG1 1 
ATOM 1667 C CG2 . VAL B 1 93  ? 283.993 301.942 383.658 1.00 28.74  ? 92  VAL B CG2 1 
ATOM 1668 N N   . THR B 1 94  ? 283.859 298.486 380.396 1.00 30.07  ? 93  THR B N   1 
ATOM 1669 C CA  . THR B 1 94  ? 283.586 297.112 379.998 1.00 30.07  ? 93  THR B CA  1 
ATOM 1670 C C   . THR B 1 94  ? 284.762 296.232 380.373 1.00 30.07  ? 93  THR B C   1 
ATOM 1671 O O   . THR B 1 94  ? 285.896 296.508 379.982 1.00 30.07  ? 93  THR B O   1 
ATOM 1672 C CB  . THR B 1 94  ? 283.331 296.978 378.500 1.00 30.07  ? 93  THR B CB  1 
ATOM 1673 O OG1 . THR B 1 94  ? 284.542 297.231 377.789 1.00 30.07  ? 93  THR B OG1 1 
ATOM 1674 C CG2 . THR B 1 94  ? 282.281 297.962 378.037 1.00 30.07  ? 93  THR B CG2 1 
ATOM 1675 N N   . PHE B 1 95  ? 284.484 295.181 381.124 1.00 31.88  ? 94  PHE B N   1 
ATOM 1676 C CA  . PHE B 1 95  ? 285.452 294.157 381.461 1.00 31.88  ? 94  PHE B CA  1 
ATOM 1677 C C   . PHE B 1 95  ? 285.268 292.962 380.539 1.00 31.88  ? 94  PHE B C   1 
ATOM 1678 O O   . PHE B 1 95  ? 284.200 292.758 379.968 1.00 31.88  ? 94  PHE B O   1 
ATOM 1679 C CB  . PHE B 1 95  ? 285.286 293.736 382.915 1.00 31.88  ? 94  PHE B CB  1 
ATOM 1680 C CG  . PHE B 1 95  ? 285.682 294.790 383.893 1.00 31.88  ? 94  PHE B CG  1 
ATOM 1681 C CD1 . PHE B 1 95  ? 286.985 294.899 384.310 1.00 31.88  ? 94  PHE B CD1 1 
ATOM 1682 C CD2 . PHE B 1 95  ? 284.758 295.693 384.366 1.00 31.88  ? 94  PHE B CD2 1 
ATOM 1683 C CE1 . PHE B 1 95  ? 287.354 295.865 385.212 1.00 31.88  ? 94  PHE B CE1 1 
ATOM 1684 C CE2 . PHE B 1 95  ? 285.122 296.665 385.265 1.00 31.88  ? 94  PHE B CE2 1 
ATOM 1685 C CZ  . PHE B 1 95  ? 286.422 296.758 385.676 1.00 31.88  ? 94  PHE B CZ  1 
ATOM 1686 N N   . SER B 1 96  ? 286.324 292.170 380.391 1.00 36.63  ? 95  SER B N   1 
ATOM 1687 C CA  . SER B 1 96  ? 286.252 291.004 379.520 1.00 36.63  ? 95  SER B CA  1 
ATOM 1688 C C   . SER B 1 96  ? 287.225 289.948 380.011 1.00 36.63  ? 95  SER B C   1 
ATOM 1689 O O   . SER B 1 96  ? 288.420 290.217 380.123 1.00 36.63  ? 95  SER B O   1 
ATOM 1690 C CB  . SER B 1 96  ? 286.553 291.388 378.079 1.00 36.63  ? 95  SER B CB  1 
ATOM 1691 O OG  . SER B 1 96  ? 286.503 290.251 377.244 1.00 36.63  ? 95  SER B OG  1 
ATOM 1692 N N   . PHE B 1 97  ? 286.714 288.753 380.296 1.00 37.68  ? 96  PHE B N   1 
ATOM 1693 C CA  . PHE B 1 97  ? 287.513 287.653 380.812 1.00 37.68  ? 96  PHE B CA  1 
ATOM 1694 C C   . PHE B 1 97  ? 287.135 286.390 380.058 1.00 37.68  ? 96  PHE B C   1 
ATOM 1695 O O   . PHE B 1 97  ? 286.106 286.333 379.386 1.00 37.68  ? 96  PHE B O   1 
ATOM 1696 C CB  . PHE B 1 97  ? 287.276 287.449 382.306 1.00 37.68  ? 96  PHE B CB  1 
ATOM 1697 C CG  . PHE B 1 97  ? 287.422 288.691 383.107 1.00 37.68  ? 96  PHE B CG  1 
ATOM 1698 C CD1 . PHE B 1 97  ? 288.666 289.204 383.404 1.00 37.68  ? 96  PHE B CD1 1 
ATOM 1699 C CD2 . PHE B 1 97  ? 286.302 289.341 383.577 1.00 37.68  ? 96  PHE B CD2 1 
ATOM 1700 C CE1 . PHE B 1 97  ? 288.787 290.355 384.140 1.00 37.68  ? 96  PHE B CE1 1 
ATOM 1701 C CE2 . PHE B 1 97  ? 286.419 290.486 384.310 1.00 37.68  ? 96  PHE B CE2 1 
ATOM 1702 C CZ  . PHE B 1 97  ? 287.663 290.993 384.593 1.00 37.68  ? 96  PHE B CZ  1 
ATOM 1703 N N   . THR B 1 98  ? 287.963 285.364 380.178 1.00 41.05  ? 97  THR B N   1 
ATOM 1704 C CA  . THR B 1 98  ? 287.728 284.108 379.490 1.00 41.05  ? 97  THR B CA  1 
ATOM 1705 C C   . THR B 1 98  ? 287.192 283.074 380.472 1.00 41.05  ? 97  THR B C   1 
ATOM 1706 O O   . THR B 1 98  ? 286.954 283.365 381.646 1.00 41.05  ? 97  THR B O   1 
ATOM 1707 C CB  . THR B 1 98  ? 289.007 283.623 378.820 1.00 41.05  ? 97  THR B CB  1 
ATOM 1708 O OG1 . THR B 1 98  ? 289.980 283.340 379.825 1.00 41.05  ? 97  THR B OG1 1 
ATOM 1709 C CG2 . THR B 1 98  ? 289.555 284.687 377.905 1.00 41.05  ? 97  THR B CG2 1 
ATOM 1710 N N   . GLN B 1 99  ? 286.999 281.847 379.996 1.00 44.68  ? 98  GLN B N   1 
ATOM 1711 C CA  . GLN B 1 99  ? 286.448 280.792 380.835 1.00 44.68  ? 98  GLN B CA  1 
ATOM 1712 C C   . GLN B 1 99  ? 287.438 280.244 381.845 1.00 44.68  ? 98  GLN B C   1 
ATOM 1713 O O   . GLN B 1 99  ? 287.014 279.664 382.844 1.00 44.68  ? 98  GLN B O   1 
ATOM 1714 C CB  . GLN B 1 99  ? 285.964 279.622 379.993 1.00 44.68  ? 98  GLN B CB  1 
ATOM 1715 C CG  . GLN B 1 99  ? 284.750 279.882 379.159 1.00 44.68  ? 98  GLN B CG  1 
ATOM 1716 C CD  . GLN B 1 99  ? 284.352 278.653 378.377 1.00 44.68  ? 98  GLN B CD  1 
ATOM 1717 O OE1 . GLN B 1 99  ? 285.048 277.640 378.406 1.00 44.68  ? 98  GLN B OE1 1 
ATOM 1718 N NE2 . GLN B 1 99  ? 283.227 278.731 377.678 1.00 44.68  ? 98  GLN B NE2 1 
ATOM 1719 N N   . TYR B 1 100 ? 288.736 280.385 381.609 1.00 46.11  ? 99  TYR B N   1 
ATOM 1720 C CA  . TYR B 1 100 ? 289.732 279.747 382.458 1.00 46.11  ? 99  TYR B CA  1 
ATOM 1721 C C   . TYR B 1 100 ? 290.427 280.719 383.392 1.00 46.11  ? 99  TYR B C   1 
ATOM 1722 O O   . TYR B 1 100 ? 291.380 280.332 384.072 1.00 46.11  ? 99  TYR B O   1 
ATOM 1723 C CB  . TYR B 1 100 ? 290.752 279.014 381.596 1.00 46.11  ? 99  TYR B CB  1 
ATOM 1724 C CG  . TYR B 1 100 ? 290.160 277.816 380.915 1.00 46.11  ? 99  TYR B CG  1 
ATOM 1725 C CD1 . TYR B 1 100 ? 290.027 276.615 381.589 1.00 46.11  ? 99  TYR B CD1 1 
ATOM 1726 C CD2 . TYR B 1 100 ? 289.696 277.895 379.612 1.00 46.11  ? 99  TYR B CD2 1 
ATOM 1727 C CE1 . TYR B 1 100 ? 289.467 275.521 380.979 1.00 46.11  ? 99  TYR B CE1 1 
ATOM 1728 C CE2 . TYR B 1 100 ? 289.137 276.807 378.992 1.00 46.11  ? 99  TYR B CE2 1 
ATOM 1729 C CZ  . TYR B 1 100 ? 289.026 275.622 379.681 1.00 46.11  ? 99  TYR B CZ  1 
ATOM 1730 O OH  . TYR B 1 100 ? 288.470 274.526 379.069 1.00 46.11  ? 99  TYR B OH  1 
ATOM 1731 N N   . SER B 1 101 ? 289.970 281.960 383.455 1.00 42.80  ? 100 SER B N   1 
ATOM 1732 C CA  . SER B 1 101 ? 290.577 282.933 384.346 1.00 42.80  ? 100 SER B CA  1 
ATOM 1733 C C   . SER B 1 101 ? 290.167 282.668 385.784 1.00 42.80  ? 100 SER B C   1 
ATOM 1734 O O   . SER B 1 101 ? 288.982 282.509 386.081 1.00 42.80  ? 100 SER B O   1 
ATOM 1735 C CB  . SER B 1 101 ? 290.157 284.336 383.945 1.00 42.80  ? 100 SER B CB  1 
ATOM 1736 O OG  . SER B 1 101 ? 288.767 284.486 384.130 1.00 42.80  ? 100 SER B OG  1 
ATOM 1737 N N   . THR B 1 102 ? 291.143 282.642 386.682 1.00 44.11  ? 101 THR B N   1 
ATOM 1738 C CA  . THR B 1 102 ? 290.841 282.518 388.094 1.00 44.11  ? 101 THR B CA  1 
ATOM 1739 C C   . THR B 1 102 ? 290.343 283.852 388.639 1.00 44.11  ? 101 THR B C   1 
ATOM 1740 O O   . THR B 1 102 ? 290.401 284.882 387.972 1.00 44.11  ? 101 THR B O   1 
ATOM 1741 C CB  . THR B 1 102 ? 292.071 282.060 388.866 1.00 44.11  ? 101 THR B CB  1 
ATOM 1742 O OG1 . THR B 1 102 ? 293.073 283.077 388.815 1.00 44.11  ? 101 THR B OG1 1 
ATOM 1743 C CG2 . THR B 1 102 ? 292.635 280.801 388.242 1.00 44.11  ? 101 THR B CG2 1 
ATOM 1744 N N   . ASP B 1 103 ? 289.856 283.830 389.879 1.00 44.98  ? 102 ASP B N   1 
ATOM 1745 C CA  . ASP B 1 103 ? 289.273 285.029 390.467 1.00 44.98  ? 102 ASP B CA  1 
ATOM 1746 C C   . ASP B 1 103 ? 290.308 286.046 390.919 1.00 44.98  ? 102 ASP B C   1 
ATOM 1747 O O   . ASP B 1 103 ? 289.959 287.212 391.110 1.00 44.98  ? 102 ASP B O   1 
ATOM 1748 C CB  . ASP B 1 103 ? 288.366 284.662 391.642 1.00 44.98  ? 102 ASP B CB  1 
ATOM 1749 C CG  . ASP B 1 103 ? 289.065 283.818 392.687 1.00 44.98  ? 102 ASP B CG  1 
ATOM 1750 O OD1 . ASP B 1 103 ? 290.216 283.391 392.465 1.00 44.98  ? 102 ASP B OD1 1 
ATOM 1751 O OD2 . ASP B 1 103 ? 288.454 283.578 393.747 1.00 44.98  ? 102 ASP B OD2 1 
ATOM 1752 N N   . GLU B 1 104 ? 291.561 285.638 391.112 1.00 46.22  ? 103 GLU B N   1 
ATOM 1753 C CA  . GLU B 1 104 ? 292.587 286.611 391.465 1.00 46.22  ? 103 GLU B CA  1 
ATOM 1754 C C   . GLU B 1 104 ? 293.006 287.436 390.261 1.00 46.22  ? 103 GLU B C   1 
ATOM 1755 O O   . GLU B 1 104 ? 293.428 288.585 390.416 1.00 46.22  ? 103 GLU B O   1 
ATOM 1756 C CB  . GLU B 1 104 ? 293.795 285.917 392.078 1.00 46.22  ? 103 GLU B CB  1 
ATOM 1757 C CG  . GLU B 1 104 ? 293.523 285.314 393.439 1.00 46.22  ? 103 GLU B CG  1 
ATOM 1758 C CD  . GLU B 1 104 ? 294.745 284.640 394.025 1.00 46.22  ? 103 GLU B CD  1 
ATOM 1759 O OE1 . GLU B 1 104 ? 295.766 284.536 393.316 1.00 46.22  ? 103 GLU B OE1 1 
ATOM 1760 O OE2 . GLU B 1 104 ? 294.685 284.213 395.198 1.00 46.22  ? 103 GLU B OE2 1 
ATOM 1761 N N   . GLU B 1 105 ? 292.901 286.869 389.059 1.00 44.96  ? 104 GLU B N   1 
ATOM 1762 C CA  . GLU B 1 105 ? 293.119 287.651 387.852 1.00 44.96  ? 104 GLU B CA  1 
ATOM 1763 C C   . GLU B 1 105 ? 292.009 288.663 387.638 1.00 44.96  ? 104 GLU B C   1 
ATOM 1764 O O   . GLU B 1 105 ? 292.249 289.739 387.085 1.00 44.96  ? 104 GLU B O   1 
ATOM 1765 C CB  . GLU B 1 105 ? 293.202 286.729 386.643 1.00 44.96  ? 104 GLU B CB  1 
ATOM 1766 C CG  . GLU B 1 105 ? 294.336 285.735 386.692 1.00 44.96  ? 104 GLU B CG  1 
ATOM 1767 C CD  . GLU B 1 105 ? 294.320 284.804 385.502 1.00 44.96  ? 104 GLU B CD  1 
ATOM 1768 O OE1 . GLU B 1 105 ? 293.394 284.923 384.676 1.00 44.96  ? 104 GLU B OE1 1 
ATOM 1769 O OE2 . GLU B 1 105 ? 295.210 283.937 385.407 1.00 44.96  ? 104 GLU B OE2 1 
ATOM 1770 N N   . ARG B 1 106 ? 290.787 288.326 388.045 1.00 39.51  ? 105 ARG B N   1 
ATOM 1771 C CA  . ARG B 1 106 ? 289.668 289.239 387.890 1.00 39.51  ? 105 ARG B CA  1 
ATOM 1772 C C   . ARG B 1 106 ? 289.662 290.315 388.961 1.00 39.51  ? 105 ARG B C   1 
ATOM 1773 O O   . ARG B 1 106 ? 289.147 291.411 388.728 1.00 39.51  ? 105 ARG B O   1 
ATOM 1774 C CB  . ARG B 1 106 ? 288.351 288.471 387.924 1.00 39.51  ? 105 ARG B CB  1 
ATOM 1775 C CG  . ARG B 1 106 ? 288.087 287.588 386.723 1.00 39.51  ? 105 ARG B CG  1 
ATOM 1776 C CD  . ARG B 1 106 ? 286.663 287.084 386.769 1.00 39.51  ? 105 ARG B CD  1 
ATOM 1777 N NE  . ARG B 1 106 ? 286.435 286.230 387.924 1.00 39.51  ? 105 ARG B NE  1 
ATOM 1778 C CZ  . ARG B 1 106 ? 286.465 284.908 387.880 1.00 39.51  ? 105 ARG B CZ  1 
ATOM 1779 N NH1 . ARG B 1 106 ? 286.669 284.298 386.729 1.00 39.51  ? 105 ARG B NH1 1 
ATOM 1780 N NH2 . ARG B 1 106 ? 286.258 284.198 388.973 1.00 39.51  ? 105 ARG B NH2 1 
ATOM 1781 N N   . ALA B 1 107 ? 290.210 290.023 390.135 1.00 39.26  ? 106 ALA B N   1 
ATOM 1782 C CA  . ALA B 1 107 ? 290.298 291.014 391.193 1.00 39.26  ? 106 ALA B CA  1 
ATOM 1783 C C   . ALA B 1 107 ? 291.526 291.890 391.063 1.00 39.26  ? 106 ALA B C   1 
ATOM 1784 O O   . ALA B 1 107 ? 291.600 292.929 391.724 1.00 39.26  ? 106 ALA B O   1 
ATOM 1785 C CB  . ALA B 1 107 ? 290.303 290.333 392.558 1.00 39.26  ? 106 ALA B CB  1 
ATOM 1786 N N   . PHE B 1 108 ? 292.494 291.493 390.246 1.00 38.61  ? 107 PHE B N   1 
ATOM 1787 C CA  . PHE B 1 108 ? 293.622 292.371 389.987 1.00 38.61  ? 107 PHE B CA  1 
ATOM 1788 C C   . PHE B 1 108 ? 293.201 293.515 389.083 1.00 38.61  ? 107 PHE B C   1 
ATOM 1789 O O   . PHE B 1 108 ? 293.569 294.665 389.326 1.00 38.61  ? 107 PHE B O   1 
ATOM 1790 C CB  . PHE B 1 108 ? 294.767 291.575 389.366 1.00 38.61  ? 107 PHE B CB  1 
ATOM 1791 C CG  . PHE B 1 108 ? 296.073 292.305 389.333 1.00 38.61  ? 107 PHE B CG  1 
ATOM 1792 C CD1 . PHE B 1 108 ? 296.852 292.397 390.472 1.00 38.61  ? 107 PHE B CD1 1 
ATOM 1793 C CD2 . PHE B 1 108 ? 296.529 292.888 388.168 1.00 38.61  ? 107 PHE B CD2 1 
ATOM 1794 C CE1 . PHE B 1 108 ? 298.057 293.059 390.447 1.00 38.61  ? 107 PHE B CE1 1 
ATOM 1795 C CE2 . PHE B 1 108 ? 297.733 293.550 388.141 1.00 38.61  ? 107 PHE B CE2 1 
ATOM 1796 C CZ  . PHE B 1 108 ? 298.494 293.633 389.283 1.00 38.61  ? 107 PHE B CZ  1 
ATOM 1797 N N   . VAL B 1 109 ? 292.396 293.221 388.058 1.00 36.63  ? 108 VAL B N   1 
ATOM 1798 C CA  . VAL B 1 109 ? 291.945 294.232 387.104 1.00 36.63  ? 108 VAL B CA  1 
ATOM 1799 C C   . VAL B 1 109 ? 290.980 295.213 387.761 1.00 36.63  ? 108 VAL B C   1 
ATOM 1800 O O   . VAL B 1 109 ? 290.994 296.409 387.450 1.00 36.63  ? 108 VAL B O   1 
ATOM 1801 C CB  . VAL B 1 109 ? 291.319 293.526 385.887 1.00 36.63  ? 108 VAL B CB  1 
ATOM 1802 C CG1 . VAL B 1 109 ? 290.830 294.510 384.861 1.00 36.63  ? 108 VAL B CG1 1 
ATOM 1803 C CG2 . VAL B 1 109 ? 292.310 292.595 385.266 1.00 36.63  ? 108 VAL B CG2 1 
ATOM 1804 N N   . ARG B 1 110 ? 290.150 294.738 388.691 1.00 36.38  ? 109 ARG B N   1 
ATOM 1805 C CA  . ARG B 1 110 ? 289.236 295.621 389.409 1.00 36.38  ? 109 ARG B CA  1 
ATOM 1806 C C   . ARG B 1 110 ? 289.985 296.602 390.301 1.00 36.38  ? 109 ARG B C   1 
ATOM 1807 O O   . ARG B 1 110 ? 289.668 297.794 390.321 1.00 36.38  ? 109 ARG B O   1 
ATOM 1808 C CB  . ARG B 1 110 ? 288.261 294.792 390.239 1.00 36.38  ? 109 ARG B CB  1 
ATOM 1809 C CG  . ARG B 1 110 ? 287.340 295.613 391.096 1.00 36.38  ? 109 ARG B CG  1 
ATOM 1810 C CD  . ARG B 1 110 ? 286.457 294.745 391.961 1.00 36.38  ? 109 ARG B CD  1 
ATOM 1811 N NE  . ARG B 1 110 ? 287.226 293.904 392.869 1.00 36.38  ? 109 ARG B NE  1 
ATOM 1812 C CZ  . ARG B 1 110 ? 287.726 294.306 394.030 1.00 36.38  ? 109 ARG B CZ  1 
ATOM 1813 N NH1 . ARG B 1 110 ? 287.561 295.551 394.441 1.00 36.38  ? 109 ARG B NH1 1 
ATOM 1814 N NH2 . ARG B 1 110 ? 288.401 293.454 394.783 1.00 36.38  ? 109 ARG B NH2 1 
ATOM 1815 N N   . THR B 1 111 ? 290.987 296.127 391.037 1.00 37.61  ? 110 THR B N   1 
ATOM 1816 C CA  . THR B 1 111 ? 291.724 297.008 391.930 1.00 37.61  ? 110 THR B CA  1 
ATOM 1817 C C   . THR B 1 111 ? 292.812 297.798 391.221 1.00 37.61  ? 110 THR B C   1 
ATOM 1818 O O   . THR B 1 111 ? 293.296 298.784 391.780 1.00 37.61  ? 110 THR B O   1 
ATOM 1819 C CB  . THR B 1 111 ? 292.337 296.206 393.068 1.00 37.61  ? 110 THR B CB  1 
ATOM 1820 O OG1 . THR B 1 111 ? 293.204 295.210 392.524 1.00 37.61  ? 110 THR B OG1 1 
ATOM 1821 C CG2 . THR B 1 111 ? 291.261 295.540 393.863 1.00 37.61  ? 110 THR B CG2 1 
ATOM 1822 N N   . GLU B 1 112 ? 293.209 297.391 390.016 1.00 36.41  ? 111 GLU B N   1 
ATOM 1823 C CA  . GLU B 1 112 ? 294.117 298.211 389.221 1.00 36.41  ? 111 GLU B CA  1 
ATOM 1824 C C   . GLU B 1 112 ? 293.405 299.431 388.668 1.00 36.41  ? 111 GLU B C   1 
ATOM 1825 O O   . GLU B 1 112 ? 293.962 300.532 388.652 1.00 36.41  ? 111 GLU B O   1 
ATOM 1826 C CB  . GLU B 1 112 ? 294.697 297.390 388.076 1.00 36.41  ? 111 GLU B CB  1 
ATOM 1827 C CG  . GLU B 1 112 ? 295.700 298.104 387.211 1.00 36.41  ? 111 GLU B CG  1 
ATOM 1828 C CD  . GLU B 1 112 ? 296.225 297.208 386.118 1.00 36.41  ? 111 GLU B CD  1 
ATOM 1829 O OE1 . GLU B 1 112 ? 295.792 296.044 386.055 1.00 36.41  ? 111 GLU B OE1 1 
ATOM 1830 O OE2 . GLU B 1 112 ? 297.061 297.664 385.313 1.00 36.41  ? 111 GLU B OE2 1 
ATOM 1831 N N   . LEU B 1 113 ? 292.174 299.248 388.206 1.00 34.94  ? 112 LEU B N   1 
ATOM 1832 C CA  . LEU B 1 113 ? 291.418 300.353 387.647 1.00 34.94  ? 112 LEU B CA  1 
ATOM 1833 C C   . LEU B 1 113 ? 290.974 301.326 388.725 1.00 34.94  ? 112 LEU B C   1 
ATOM 1834 O O   . LEU B 1 113 ? 290.891 302.530 388.473 1.00 34.94  ? 112 LEU B O   1 
ATOM 1835 C CB  . LEU B 1 113 ? 290.223 299.802 386.884 1.00 34.94  ? 112 LEU B CB  1 
ATOM 1836 C CG  . LEU B 1 113 ? 289.411 300.812 386.098 1.00 34.94  ? 112 LEU B CG  1 
ATOM 1837 C CD1 . LEU B 1 113 ? 290.314 301.410 385.063 1.00 34.94  ? 112 LEU B CD1 1 
ATOM 1838 C CD2 . LEU B 1 113 ? 288.254 300.099 385.469 1.00 34.94  ? 112 LEU B CD2 1 
ATOM 1839 N N   . ALA B 1 114 ? 290.713 300.840 389.935 1.00 35.82  ? 113 ALA B N   1 
ATOM 1840 C CA  . ALA B 1 114 ? 290.405 301.739 391.037 1.00 35.82  ? 113 ALA B CA  1 
ATOM 1841 C C   . ALA B 1 114 ? 291.623 302.522 391.503 1.00 35.82  ? 113 ALA B C   1 
ATOM 1842 O O   . ALA B 1 114 ? 291.464 303.569 392.138 1.00 35.82  ? 113 ALA B O   1 
ATOM 1843 C CB  . ALA B 1 114 ? 289.824 300.951 392.206 1.00 35.82  ? 113 ALA B CB  1 
ATOM 1844 N N   . ALA B 1 115 ? 292.828 302.048 391.208 1.00 36.34  ? 114 ALA B N   1 
ATOM 1845 C CA  . ALA B 1 115 ? 294.039 302.751 391.603 1.00 36.34  ? 114 ALA B CA  1 
ATOM 1846 C C   . ALA B 1 115 ? 294.578 303.659 390.512 1.00 36.34  ? 114 ALA B C   1 
ATOM 1847 O O   . ALA B 1 115 ? 295.326 304.591 390.820 1.00 36.34  ? 114 ALA B O   1 
ATOM 1848 C CB  . ALA B 1 115 ? 295.121 301.752 392.013 1.00 36.34  ? 114 ALA B CB  1 
ATOM 1849 N N   . LEU B 1 116 ? 294.237 303.404 389.248 1.00 36.74  ? 115 LEU B N   1 
ATOM 1850 C CA  . LEU B 1 116 ? 294.631 304.321 388.187 1.00 36.74  ? 115 LEU B CA  1 
ATOM 1851 C C   . LEU B 1 116 ? 293.821 305.600 388.218 1.00 36.74  ? 115 LEU B C   1 
ATOM 1852 O O   . LEU B 1 116 ? 294.347 306.665 387.893 1.00 36.74  ? 115 LEU B O   1 
ATOM 1853 C CB  . LEU B 1 116 ? 294.495 303.661 386.823 1.00 36.74  ? 115 LEU B CB  1 
ATOM 1854 C CG  . LEU B 1 116 ? 295.598 302.674 386.493 1.00 36.74  ? 115 LEU B CG  1 
ATOM 1855 C CD1 . LEU B 1 116 ? 295.293 302.009 385.186 1.00 36.74  ? 115 LEU B CD1 1 
ATOM 1856 C CD2 . LEU B 1 116 ? 296.892 303.435 386.400 1.00 36.74  ? 115 LEU B CD2 1 
ATOM 1857 N N   . LEU B 1 117 ? 292.559 305.527 388.630 1.00 34.29  ? 116 LEU B N   1 
ATOM 1858 C CA  . LEU B 1 117 ? 291.690 306.694 388.623 1.00 34.29  ? 116 LEU B CA  1 
ATOM 1859 C C   . LEU B 1 117 ? 292.039 307.712 389.700 1.00 34.29  ? 116 LEU B C   1 
ATOM 1860 O O   . LEU B 1 117 ? 291.500 308.819 389.670 1.00 34.29  ? 116 LEU B O   1 
ATOM 1861 C CB  . LEU B 1 117 ? 290.242 306.252 388.787 1.00 34.29  ? 116 LEU B CB  1 
ATOM 1862 C CG  . LEU B 1 117 ? 289.663 305.441 387.635 1.00 34.29  ? 116 LEU B CG  1 
ATOM 1863 C CD1 . LEU B 1 117 ? 288.329 304.886 388.031 1.00 34.29  ? 116 LEU B CD1 1 
ATOM 1864 C CD2 . LEU B 1 117 ? 289.524 306.293 386.408 1.00 34.29  ? 116 LEU B CD2 1 
ATOM 1865 N N   . ALA B 1 118 ? 292.927 307.380 390.635 1.00 36.48  ? 117 ALA B N   1 
ATOM 1866 C CA  . ALA B 1 118 ? 293.330 308.288 391.698 1.00 36.48  ? 117 ALA B CA  1 
ATOM 1867 C C   . ALA B 1 118 ? 294.804 308.659 391.626 1.00 36.48  ? 117 ALA B C   1 
ATOM 1868 O O   . ALA B 1 118 ? 295.367 309.107 392.627 1.00 36.48  ? 117 ALA B O   1 
ATOM 1869 C CB  . ALA B 1 118 ? 293.015 307.670 393.059 1.00 36.48  ? 117 ALA B CB  1 
ATOM 1870 N N   . SER B 1 119 ? 295.441 308.474 390.481 1.00 37.85  ? 118 SER B N   1 
ATOM 1871 C CA  . SER B 1 119 ? 296.840 308.714 390.173 1.00 37.85  ? 118 SER B CA  1 
ATOM 1872 C C   . SER B 1 119 ? 296.993 310.033 389.428 1.00 37.85  ? 118 SER B C   1 
ATOM 1873 O O   . SER B 1 119 ? 296.118 310.397 388.643 1.00 37.85  ? 118 SER B O   1 
ATOM 1874 C CB  . SER B 1 119 ? 297.395 307.579 389.312 1.00 37.85  ? 118 SER B CB  1 
ATOM 1875 O OG  . SER B 1 119 ? 296.836 307.613 388.015 1.00 37.85  ? 118 SER B OG  1 
ATOM 1876 N N   . PRO B 1 120 ? 298.096 310.770 389.617 1.00 39.05  ? 119 PRO B N   1 
ATOM 1877 C CA  . PRO B 1 120 ? 298.203 312.113 389.024 1.00 39.05  ? 119 PRO B CA  1 
ATOM 1878 C C   . PRO B 1 120 ? 298.315 312.139 387.510 1.00 39.05  ? 119 PRO B C   1 
ATOM 1879 O O   . PRO B 1 120 ? 298.268 313.225 386.927 1.00 39.05  ? 119 PRO B O   1 
ATOM 1880 C CB  . PRO B 1 120 ? 299.474 312.675 389.664 1.00 39.05  ? 119 PRO B CB  1 
ATOM 1881 C CG  . PRO B 1 120 ? 300.264 311.491 390.019 1.00 39.05  ? 119 PRO B CG  1 
ATOM 1882 C CD  . PRO B 1 120 ? 299.280 310.448 390.431 1.00 39.05  ? 119 PRO B CD  1 
ATOM 1883 N N   . LEU B 1 121 ? 298.461 310.993 386.855 1.00 40.37  ? 120 LEU B N   1 
ATOM 1884 C CA  . LEU B 1 121 ? 298.413 310.959 385.402 1.00 40.37  ? 120 LEU B CA  1 
ATOM 1885 C C   . LEU B 1 121 ? 296.979 310.958 384.899 1.00 40.37  ? 120 LEU B C   1 
ATOM 1886 O O   . LEU B 1 121 ? 296.704 311.509 383.830 1.00 40.37  ? 120 LEU B O   1 
ATOM 1887 C CB  . LEU B 1 121 ? 299.176 309.731 384.893 1.00 40.37  ? 120 LEU B CB  1 
ATOM 1888 C CG  . LEU B 1 121 ? 299.590 309.528 383.427 1.00 40.37  ? 120 LEU B CG  1 
ATOM 1889 C CD1 . LEU B 1 121 ? 298.509 308.932 382.546 1.00 40.37  ? 120 LEU B CD1 1 
ATOM 1890 C CD2 . LEU B 1 121 ? 300.052 310.848 382.857 1.00 40.37  ? 120 LEU B CD2 1 
ATOM 1891 N N   . LEU B 1 122 ? 296.061 310.348 385.643 1.00 37.97  ? 121 LEU B N   1 
ATOM 1892 C CA  . LEU B 1 122 ? 294.672 310.262 385.218 1.00 37.97  ? 121 LEU B CA  1 
ATOM 1893 C C   . LEU B 1 122 ? 293.773 311.321 385.826 1.00 37.97  ? 121 LEU B C   1 
ATOM 1894 O O   . LEU B 1 122 ? 292.711 311.591 385.266 1.00 37.97  ? 121 LEU B O   1 
ATOM 1895 C CB  . LEU B 1 122 ? 294.079 308.890 385.539 1.00 37.97  ? 121 LEU B CB  1 
ATOM 1896 C CG  . LEU B 1 122 ? 294.169 307.796 384.480 1.00 37.97  ? 121 LEU B CG  1 
ATOM 1897 C CD1 . LEU B 1 122 ? 293.509 308.323 383.246 1.00 37.97  ? 121 LEU B CD1 1 
ATOM 1898 C CD2 . LEU B 1 122 ? 295.578 307.349 384.192 1.00 37.97  ? 121 LEU B CD2 1 
ATOM 1899 N N   . ILE B 1 123 ? 294.148 311.933 386.954 1.00 38.19  ? 122 ILE B N   1 
ATOM 1900 C CA  . ILE B 1 123 ? 293.348 313.035 387.471 1.00 38.19  ? 122 ILE B CA  1 
ATOM 1901 C C   . ILE B 1 123 ? 293.684 314.338 386.774 1.00 38.19  ? 122 ILE B C   1 
ATOM 1902 O O   . ILE B 1 123 ? 293.080 315.371 387.081 1.00 38.19  ? 122 ILE B O   1 
ATOM 1903 C CB  . ILE B 1 123 ? 293.508 313.232 388.991 1.00 38.19  ? 122 ILE B CB  1 
ATOM 1904 C CG1 . ILE B 1 123 ? 294.857 313.836 389.325 1.00 38.19  ? 122 ILE B CG1 1 
ATOM 1905 C CG2 . ILE B 1 123 ? 293.433 311.923 389.699 1.00 38.19  ? 122 ILE B CG2 1 
ATOM 1906 C CD1 . ILE B 1 123 ? 294.967 314.258 390.762 1.00 38.19  ? 122 ILE B CD1 1 
ATOM 1907 N N   . ASP B 1 124 ? 294.642 314.328 385.854 1.00 41.69  ? 123 ASP B N   1 
ATOM 1908 C CA  . ASP B 1 124 ? 294.957 315.481 385.030 1.00 41.69  ? 123 ASP B CA  1 
ATOM 1909 C C   . ASP B 1 124 ? 294.381 315.373 383.629 1.00 41.69  ? 123 ASP B C   1 
ATOM 1910 O O   . ASP B 1 124 ? 294.108 316.400 383.008 1.00 41.69  ? 123 ASP B O   1 
ATOM 1911 C CB  . ASP B 1 124 ? 296.475 315.659 384.940 1.00 41.69  ? 123 ASP B CB  1 
ATOM 1912 C CG  . ASP B 1 124 ? 296.875 316.970 384.298 1.00 41.69  ? 123 ASP B CG  1 
ATOM 1913 O OD1 . ASP B 1 124 ? 296.792 318.014 384.975 1.00 41.69  ? 123 ASP B OD1 1 
ATOM 1914 O OD2 . ASP B 1 124 ? 297.265 316.962 383.115 1.00 41.69  ? 123 ASP B OD2 1 
ATOM 1915 N N   . ALA B 1 125 ? 294.186 314.161 383.123 1.00 38.59  ? 124 ALA B N   1 
ATOM 1916 C CA  . ALA B 1 125 ? 293.568 313.969 381.822 1.00 38.59  ? 124 ALA B CA  1 
ATOM 1917 C C   . ALA B 1 125 ? 292.052 314.012 381.870 1.00 38.59  ? 124 ALA B C   1 
ATOM 1918 O O   . ALA B 1 125 ? 291.420 314.169 380.824 1.00 38.59  ? 124 ALA B O   1 
ATOM 1919 C CB  . ALA B 1 125 ? 294.011 312.635 381.226 1.00 38.59  ? 124 ALA B CB  1 
ATOM 1920 N N   . ILE B 1 126 ? 291.456 313.871 383.048 1.00 36.94  ? 125 ILE B N   1 
ATOM 1921 C CA  . ILE B 1 126 ? 290.013 313.854 383.202 1.00 36.94  ? 125 ILE B CA  1 
ATOM 1922 C C   . ILE B 1 126 ? 289.505 315.136 383.847 1.00 36.94  ? 125 ILE B C   1 
ATOM 1923 O O   . ILE B 1 126 ? 288.490 315.689 383.421 1.00 36.94  ? 125 ILE B O   1 
ATOM 1924 C CB  . ILE B 1 126 ? 289.571 312.615 384.010 1.00 36.94  ? 125 ILE B CB  1 
ATOM 1925 C CG1 . ILE B 1 126 ? 290.015 311.342 383.302 1.00 36.94  ? 125 ILE B CG1 1 
ATOM 1926 C CG2 . ILE B 1 126 ? 288.073 312.577 384.177 1.00 36.94  ? 125 ILE B CG2 1 
ATOM 1927 C CD1 . ILE B 1 126 ? 289.875 310.109 384.144 1.00 36.94  ? 125 ILE B CD1 1 
ATOM 1928 N N   . ASP B 1 127 ? 290.210 315.647 384.850 1.00 39.27  ? 126 ASP B N   1 
ATOM 1929 C CA  . ASP B 1 127 ? 289.758 316.893 385.447 1.00 39.27  ? 126 ASP B CA  1 
ATOM 1930 C C   . ASP B 1 127 ? 290.133 318.085 384.582 1.00 39.27  ? 126 ASP B C   1 
ATOM 1931 O O   . ASP B 1 127 ? 289.329 319.006 384.410 1.00 39.27  ? 126 ASP B O   1 
ATOM 1932 C CB  . ASP B 1 127 ? 290.337 317.052 386.846 1.00 39.27  ? 126 ASP B CB  1 
ATOM 1933 C CG  . ASP B 1 127 ? 289.955 315.920 387.757 1.00 39.27  ? 126 ASP B CG  1 
ATOM 1934 O OD1 . ASP B 1 127 ? 288.981 315.220 387.436 1.00 39.27  ? 126 ASP B OD1 1 
ATOM 1935 O OD2 . ASP B 1 127 ? 290.600 315.747 388.808 1.00 39.27  ? 126 ASP B OD2 1 
ATOM 1936 N N   . GLN B 1 128 ? 291.329 318.076 384.007 1.00 40.37  ? 127 GLN B N   1 
ATOM 1937 C CA  . GLN B 1 128 ? 291.836 319.231 383.289 1.00 40.37  ? 127 GLN B CA  1 
ATOM 1938 C C   . GLN B 1 128 ? 291.796 319.064 381.780 1.00 40.37  ? 127 GLN B C   1 
ATOM 1939 O O   . GLN B 1 128 ? 291.952 320.060 381.069 1.00 40.37  ? 127 GLN B O   1 
ATOM 1940 C CB  . GLN B 1 128 ? 293.269 319.516 383.729 1.00 40.37  ? 127 GLN B CB  1 
ATOM 1941 C CG  . GLN B 1 128 ? 293.406 319.735 385.216 1.00 40.37  ? 127 GLN B CG  1 
ATOM 1942 C CD  . GLN B 1 128 ? 292.590 320.902 385.699 1.00 40.37  ? 127 GLN B CD  1 
ATOM 1943 O OE1 . GLN B 1 128 ? 291.606 320.730 386.410 1.00 40.37  ? 127 GLN B OE1 1 
ATOM 1944 N NE2 . GLN B 1 128 ? 292.988 322.103 385.308 1.00 40.37  ? 127 GLN B NE2 1 
ATOM 1945 N N   . LEU B 1 129 ? 291.602 317.834 381.296 1.00 38.53  ? 128 LEU B N   1 
ATOM 1946 C CA  . LEU B 1 129 ? 291.546 317.477 379.872 1.00 38.53  ? 128 LEU B CA  1 
ATOM 1947 C C   . LEU B 1 129 ? 292.851 317.814 379.153 1.00 38.53  ? 128 LEU B C   1 
ATOM 1948 O O   . LEU B 1 129 ? 292.892 318.569 378.184 1.00 38.53  ? 128 LEU B O   1 
ATOM 1949 C CB  . LEU B 1 129 ? 290.329 318.105 379.180 1.00 38.53  ? 128 LEU B CB  1 
ATOM 1950 C CG  . LEU B 1 129 ? 289.087 317.236 378.999 1.00 38.53  ? 128 LEU B CG  1 
ATOM 1951 C CD1 . LEU B 1 129 ? 288.686 316.600 380.268 1.00 38.53  ? 128 LEU B CD1 1 
ATOM 1952 C CD2 . LEU B 1 129 ? 287.970 318.145 378.591 1.00 38.53  ? 128 LEU B CD2 1 
ATOM 1953 N N   . ASN B 1 130 ? 293.922 317.199 379.643 1.00 41.31  ? 129 ASN B N   1 
ATOM 1954 C CA  . ASN B 1 130 ? 295.253 317.333 379.077 1.00 41.31  ? 129 ASN B CA  1 
ATOM 1955 C C   . ASN B 1 130 ? 295.746 315.954 378.677 1.00 41.31  ? 129 ASN B C   1 
ATOM 1956 O O   . ASN B 1 130 ? 295.777 315.051 379.527 1.00 41.31  ? 129 ASN B O   1 
ATOM 1957 C CB  . ASN B 1 130 ? 296.210 317.961 380.085 1.00 41.31  ? 129 ASN B CB  1 
ATOM 1958 C CG  . ASN B 1 130 ? 295.898 319.402 380.360 1.00 41.31  ? 129 ASN B CG  1 
ATOM 1959 O OD1 . ASN B 1 130 ? 295.587 320.163 379.451 1.00 41.31  ? 129 ASN B OD1 1 
ATOM 1960 N ND2 . ASN B 1 130 ? 295.982 319.791 381.621 1.00 41.31  ? 129 ASN B ND2 1 
ATOM 1961 N N   . PRO B 1 131 ? 296.111 315.730 377.418 1.00 43.41  ? 130 PRO B N   1 
ATOM 1962 C CA  . PRO B 1 131 ? 296.737 314.460 377.046 1.00 43.41  ? 130 PRO B CA  1 
ATOM 1963 C C   . PRO B 1 131 ? 298.087 314.301 377.717 1.00 43.41  ? 130 PRO B C   1 
ATOM 1964 O O   . PRO B 1 131 ? 298.771 315.278 378.028 1.00 43.41  ? 130 PRO B O   1 
ATOM 1965 C CB  . PRO B 1 131 ? 296.883 314.569 375.527 1.00 43.41  ? 130 PRO B CB  1 
ATOM 1966 C CG  . PRO B 1 131 ? 295.849 315.563 375.126 1.00 43.41  ? 130 PRO B CG  1 
ATOM 1967 C CD  . PRO B 1 131 ? 295.803 316.555 376.241 1.00 43.41  ? 130 PRO B CD  1 
ATOM 1968 N N   . ALA B 1 132 ? 298.454 313.050 377.963 1.00 43.87  ? 131 ALA B N   1 
ATOM 1969 C CA  . ALA B 1 132 ? 299.684 312.744 378.685 1.00 43.87  ? 131 ALA B CA  1 
ATOM 1970 C C   . ALA B 1 132 ? 300.868 313.026 377.776 1.00 43.87  ? 131 ALA B C   1 
ATOM 1971 O O   . ALA B 1 132 ? 301.220 312.219 376.918 1.00 43.87  ? 131 ALA B O   1 
ATOM 1972 C CB  . ALA B 1 132 ? 299.677 311.297 379.155 1.00 43.87  ? 131 ALA B CB  1 
ATOM 1973 N N   . TYR B 1 133 ? 301.480 314.187 377.962 1.00 46.56  ? 132 TYR B N   1 
ATOM 1974 C CA  . TYR B 1 133 ? 302.620 314.590 377.163 1.00 46.56  ? 132 TYR B CA  1 
ATOM 1975 C C   . TYR B 1 133 ? 303.729 315.105 378.067 1.00 46.56  ? 132 TYR B C   1 
ATOM 1976 O O   . TYR B 1 133 ? 304.650 314.373 378.416 1.00 46.56  ? 132 TYR B O   1 
ATOM 1977 C CB  . TYR B 1 133 ? 302.213 315.660 376.152 1.00 46.56  ? 132 TYR B CB  1 
ATOM 1978 C CG  . TYR B 1 133 ? 303.340 316.105 375.257 1.00 46.56  ? 132 TYR B CG  1 
ATOM 1979 C CD1 . TYR B 1 133 ? 303.775 315.302 374.212 1.00 46.56  ? 132 TYR B CD1 1 
ATOM 1980 C CD2 . TYR B 1 133 ? 303.969 317.327 375.455 1.00 46.56  ? 132 TYR B CD2 1 
ATOM 1981 C CE1 . TYR B 1 133 ? 304.809 315.699 373.392 1.00 46.56  ? 132 TYR B CE1 1 
ATOM 1982 C CE2 . TYR B 1 133 ? 305.005 317.734 374.644 1.00 46.56  ? 132 TYR B CE2 1 
ATOM 1983 C CZ  . TYR B 1 133 ? 305.419 316.916 373.611 1.00 46.56  ? 132 TYR B CZ  1 
ATOM 1984 O OH  . TYR B 1 133 ? 306.451 317.314 372.795 1.00 46.56  ? 132 TYR B OH  1 
ATOM 1985 O OXT . TYR B 1 133 ? 303.726 316.262 378.480 1.00 46.56  ? 132 TYR B OXT 1 
ATOM 1986 N N   . ALA C 1 2   ? 259.903 281.588 392.042 1.00 46.61  ? 1   ALA C N   1 
ATOM 1987 C CA  . ALA C 1 2   ? 259.825 282.945 392.559 1.00 46.61  ? 1   ALA C CA  1 
ATOM 1988 C C   . ALA C 1 2   ? 260.958 283.781 391.999 1.00 46.61  ? 1   ALA C C   1 
ATOM 1989 O O   . ALA C 1 2   ? 261.421 283.542 390.889 1.00 46.61  ? 1   ALA C O   1 
ATOM 1990 C CB  . ALA C 1 2   ? 259.869 282.936 394.071 1.00 46.61  ? 1   ALA C CB  1 
ATOM 1991 N N   . LYS C 1 3   ? 261.398 284.776 392.758 1.00 47.11  ? 2   LYS C N   1 
ATOM 1992 C CA  . LYS C 1 3   ? 262.625 285.473 392.416 1.00 47.11  ? 2   LYS C CA  1 
ATOM 1993 C C   . LYS C 1 3   ? 263.802 284.584 392.782 1.00 47.11  ? 2   LYS C C   1 
ATOM 1994 O O   . LYS C 1 3   ? 263.767 283.879 393.793 1.00 47.11  ? 2   LYS C O   1 
ATOM 1995 C CB  . LYS C 1 3   ? 262.706 286.817 393.144 1.00 47.11  ? 2   LYS C CB  1 
ATOM 1996 C CG  . LYS C 1 3   ? 263.887 287.682 392.723 1.00 47.11  ? 2   LYS C CG  1 
ATOM 1997 C CD  . LYS C 1 3   ? 263.817 289.072 393.310 1.00 47.11  ? 2   LYS C CD  1 
ATOM 1998 C CE  . LYS C 1 3   ? 264.143 289.062 394.783 1.00 47.11  ? 2   LYS C CE  1 
ATOM 1999 N NZ  . LYS C 1 3   ? 264.189 290.442 395.328 1.00 47.11  ? 2   LYS C NZ  1 
ATOM 2000 N N   . LEU C 1 4   ? 264.823 284.582 391.926 1.00 44.81  ? 3   LEU C N   1 
ATOM 2001 C CA  . LEU C 1 4   ? 266.026 283.804 392.187 1.00 44.81  ? 3   LEU C CA  1 
ATOM 2002 C C   . LEU C 1 4   ? 266.743 284.326 393.422 1.00 44.81  ? 3   LEU C C   1 
ATOM 2003 O O   . LEU C 1 4   ? 266.881 285.537 393.610 1.00 44.81  ? 3   LEU C O   1 
ATOM 2004 C CB  . LEU C 1 4   ? 266.963 283.862 390.984 1.00 44.81  ? 3   LEU C CB  1 
ATOM 2005 C CG  . LEU C 1 4   ? 266.594 283.172 389.677 1.00 44.81  ? 3   LEU C CG  1 
ATOM 2006 C CD1 . LEU C 1 4   ? 267.619 283.512 388.614 1.00 44.81  ? 3   LEU C CD1 1 
ATOM 2007 C CD2 . LEU C 1 4   ? 266.529 281.681 389.883 1.00 44.81  ? 3   LEU C CD2 1 
ATOM 2008 N N   . GLU C 1 5   ? 267.169 283.407 394.282 1.00 45.85  ? 4   GLU C N   1 
ATOM 2009 C CA  . GLU C 1 5   ? 267.979 283.713 395.449 1.00 45.85  ? 4   GLU C CA  1 
ATOM 2010 C C   . GLU C 1 5   ? 269.074 282.662 395.538 1.00 45.85  ? 4   GLU C C   1 
ATOM 2011 O O   . GLU C 1 5   ? 269.144 281.747 394.715 1.00 45.85  ? 4   GLU C O   1 
ATOM 2012 C CB  . GLU C 1 5   ? 267.136 283.742 396.727 1.00 45.85  ? 4   GLU C CB  1 
ATOM 2013 C CG  . GLU C 1 5   ? 266.143 284.888 396.811 1.00 45.85  ? 4   GLU C CG  1 
ATOM 2014 C CD  . GLU C 1 5   ? 265.281 284.817 398.053 1.00 45.85  ? 4   GLU C CD  1 
ATOM 2015 O OE1 . GLU C 1 5   ? 265.371 283.806 398.780 1.00 45.85  ? 4   GLU C OE1 1 
ATOM 2016 O OE2 . GLU C 1 5   ? 264.512 285.769 398.301 1.00 45.85  ? 4   GLU C OE2 1 
ATOM 2017 N N   . THR C 1 6   ? 269.940 282.788 396.536 1.00 43.45  ? 5   THR C N   1 
ATOM 2018 C CA  . THR C 1 6   ? 270.981 281.793 396.738 1.00 43.45  ? 5   THR C CA  1 
ATOM 2019 C C   . THR C 1 6   ? 270.380 280.569 397.408 1.00 43.45  ? 5   THR C C   1 
ATOM 2020 O O   . THR C 1 6   ? 269.721 280.680 398.445 1.00 43.45  ? 5   THR C O   1 
ATOM 2021 C CB  . THR C 1 6   ? 272.115 282.348 397.589 1.00 43.45  ? 5   THR C CB  1 
ATOM 2022 O OG1 . THR C 1 6   ? 271.634 282.602 398.912 1.00 43.45  ? 5   THR C OG1 1 
ATOM 2023 C CG2 . THR C 1 6   ? 272.628 283.634 397.003 1.00 43.45  ? 5   THR C CG2 1 
ATOM 2024 N N   . VAL C 1 7   ? 270.605 279.404 396.813 1.00 41.49  ? 6   VAL C N   1 
ATOM 2025 C CA  . VAL C 1 7   ? 270.027 278.151 397.276 1.00 41.49  ? 6   VAL C CA  1 
ATOM 2026 C C   . VAL C 1 7   ? 271.135 277.340 397.927 1.00 41.49  ? 6   VAL C C   1 
ATOM 2027 O O   . VAL C 1 7   ? 272.152 277.051 397.290 1.00 41.49  ? 6   VAL C O   1 
ATOM 2028 C CB  . VAL C 1 7   ? 269.384 277.372 396.121 1.00 41.49  ? 6   VAL C CB  1 
ATOM 2029 C CG1 . VAL C 1 7   ? 268.836 276.056 396.613 1.00 41.49  ? 6   VAL C CG1 1 
ATOM 2030 C CG2 . VAL C 1 7   ? 268.303 278.201 395.470 1.00 41.49  ? 6   VAL C CG2 1 
ATOM 2031 N N   . THR C 1 8   ? 270.952 276.987 399.193 1.00 44.45  ? 7   THR C N   1 
ATOM 2032 C CA  . THR C 1 8   ? 271.902 276.142 399.910 1.00 44.45  ? 7   THR C CA  1 
ATOM 2033 C C   . THR C 1 8   ? 271.283 274.764 400.071 1.00 44.45  ? 7   THR C C   1 
ATOM 2034 O O   . THR C 1 8   ? 270.365 274.580 400.876 1.00 44.45  ? 7   THR C O   1 
ATOM 2035 C CB  . THR C 1 8   ? 272.263 276.726 401.272 1.00 44.45  ? 7   THR C CB  1 
ATOM 2036 O OG1 . THR C 1 8   ? 271.088 276.798 402.085 1.00 44.45  ? 7   THR C OG1 1 
ATOM 2037 C CG2 . THR C 1 8   ? 272.856 278.112 401.122 1.00 44.45  ? 7   THR C CG2 1 
ATOM 2038 N N   . LEU C 1 9   ? 271.783 273.801 399.309 1.00 46.45  ? 8   LEU C N   1 
ATOM 2039 C CA  . LEU C 1 9   ? 271.341 272.420 399.414 1.00 46.45  ? 8   LEU C CA  1 
ATOM 2040 C C   . LEU C 1 9   ? 272.191 271.725 400.465 1.00 46.45  ? 8   LEU C C   1 
ATOM 2041 O O   . LEU C 1 9   ? 273.420 271.712 400.362 1.00 46.45  ? 8   LEU C O   1 
ATOM 2042 C CB  . LEU C 1 9   ? 271.461 271.723 398.065 1.00 46.45  ? 8   LEU C CB  1 
ATOM 2043 C CG  . LEU C 1 9   ? 270.528 272.313 397.021 1.00 46.45  ? 8   LEU C CG  1 
ATOM 2044 C CD1 . LEU C 1 9   ? 270.804 271.735 395.664 1.00 46.45  ? 8   LEU C CD1 1 
ATOM 2045 C CD2 . LEU C 1 9   ? 269.101 272.059 397.415 1.00 46.45  ? 8   LEU C CD2 1 
ATOM 2046 N N   . GLY C 1 10  ? 271.545 271.160 401.476 1.00 51.53  ? 9   GLY C N   1 
ATOM 2047 C CA  . GLY C 1 10  ? 272.241 270.597 402.614 1.00 51.53  ? 9   GLY C CA  1 
ATOM 2048 C C   . GLY C 1 10  ? 272.008 269.104 402.720 1.00 51.53  ? 9   GLY C C   1 
ATOM 2049 O O   . GLY C 1 10  ? 270.972 268.594 402.290 1.00 51.53  ? 9   GLY C O   1 
ATOM 2050 N N   . ASN C 1 11  ? 272.995 268.411 403.308 1.00 56.00  ? 10  ASN C N   1 
ATOM 2051 C CA  . ASN C 1 11  ? 273.002 266.954 403.492 1.00 56.00  ? 10  ASN C CA  1 
ATOM 2052 C C   . ASN C 1 11  ? 272.847 266.217 402.164 1.00 56.00  ? 10  ASN C C   1 
ATOM 2053 O O   . ASN C 1 11  ? 272.195 265.177 402.080 1.00 56.00  ? 10  ASN C O   1 
ATOM 2054 C CB  . ASN C 1 11  ? 271.936 266.507 404.496 1.00 56.00  ? 10  ASN C CB  1 
ATOM 2055 C CG  . ASN C 1 11  ? 272.246 266.950 405.908 1.00 56.00  ? 10  ASN C CG  1 
ATOM 2056 O OD1 . ASN C 1 11  ? 273.388 266.876 406.357 1.00 56.00  ? 10  ASN C OD1 1 
ATOM 2057 N ND2 . ASN C 1 11  ? 271.230 267.422 406.616 1.00 56.00  ? 10  ASN C ND2 1 
ATOM 2058 N N   . ILE C 1 12  ? 273.440 266.774 401.119 1.00 53.24  ? 11  ILE C N   1 
ATOM 2059 C CA  . ILE C 1 12  ? 273.468 266.163 399.810 1.00 53.24  ? 11  ILE C CA  1 
ATOM 2060 C C   . ILE C 1 12  ? 274.752 265.345 399.735 1.00 53.24  ? 11  ILE C C   1 
ATOM 2061 O O   . ILE C 1 12  ? 275.678 265.526 400.527 1.00 53.24  ? 11  ILE C O   1 
ATOM 2062 C CB  . ILE C 1 12  ? 273.382 267.244 398.699 1.00 53.24  ? 11  ILE C CB  1 
ATOM 2063 C CG1 . ILE C 1 12  ? 272.950 266.667 397.355 1.00 53.24  ? 11  ILE C CG1 1 
ATOM 2064 C CG2 . ILE C 1 12  ? 274.698 267.946 398.525 1.00 53.24  ? 11  ILE C CG2 1 
ATOM 2065 C CD1 . ILE C 1 12  ? 272.595 267.723 396.343 1.00 53.24  ? 11  ILE C CD1 1 
ATOM 2066 N N   . GLY C 1 13  ? 274.804 264.402 398.808 1.00 56.25  ? 12  GLY C N   1 
ATOM 2067 C CA  . GLY C 1 13  ? 275.972 263.569 398.617 1.00 56.25  ? 12  GLY C CA  1 
ATOM 2068 C C   . GLY C 1 13  ? 275.654 262.106 398.844 1.00 56.25  ? 12  GLY C C   1 
ATOM 2069 O O   . GLY C 1 13  ? 274.512 261.718 399.080 1.00 56.25  ? 12  GLY C O   1 
ATOM 2070 N N   . LYS C 1 14  ? 276.701 261.285 398.765 1.00 56.59  ? 13  LYS C N   1 
ATOM 2071 C CA  . LYS C 1 14  ? 276.515 259.858 399.006 1.00 56.59  ? 13  LYS C CA  1 
ATOM 2072 C C   . LYS C 1 14  ? 276.340 259.572 400.489 1.00 56.59  ? 13  LYS C C   1 
ATOM 2073 O O   . LYS C 1 14  ? 275.371 258.924 400.897 1.00 56.59  ? 13  LYS C O   1 
ATOM 2074 C CB  . LYS C 1 14  ? 277.686 259.058 398.450 1.00 56.59  ? 13  LYS C CB  1 
ATOM 2075 C CG  . LYS C 1 14  ? 277.489 257.565 398.592 1.00 56.59  ? 13  LYS C CG  1 
ATOM 2076 C CD  . LYS C 1 14  ? 278.606 256.789 397.933 1.00 56.59  ? 13  LYS C CD  1 
ATOM 2077 C CE  . LYS C 1 14  ? 278.367 255.298 398.060 1.00 56.59  ? 13  LYS C CE  1 
ATOM 2078 N NZ  . LYS C 1 14  ? 279.431 254.507 397.394 1.00 56.59  ? 13  LYS C NZ  1 
ATOM 2079 N N   . ASP C 1 15  ? 277.278 260.034 401.312 1.00 61.18  ? 14  ASP C N   1 
ATOM 2080 C CA  . ASP C 1 15  ? 277.142 259.890 402.754 1.00 61.18  ? 14  ASP C CA  1 
ATOM 2081 C C   . ASP C 1 15  ? 276.096 260.824 403.343 1.00 61.18  ? 14  ASP C C   1 
ATOM 2082 O O   . ASP C 1 15  ? 275.604 260.563 404.444 1.00 61.18  ? 14  ASP C O   1 
ATOM 2083 C CB  . ASP C 1 15  ? 278.493 260.116 403.433 1.00 61.18  ? 14  ASP C CB  1 
ATOM 2084 C CG  . ASP C 1 15  ? 279.134 261.435 403.044 1.00 61.18  ? 14  ASP C CG  1 
ATOM 2085 O OD1 . ASP C 1 15  ? 278.608 262.127 402.151 1.00 61.18  ? 14  ASP C OD1 1 
ATOM 2086 O OD2 . ASP C 1 15  ? 280.173 261.786 403.638 1.00 61.18  ? 14  ASP C OD2 1 
ATOM 2087 N N   . GLY C 1 16  ? 275.748 261.895 402.640 1.00 58.32  ? 15  GLY C N   1 
ATOM 2088 C CA  . GLY C 1 16  ? 274.750 262.821 403.127 1.00 58.32  ? 15  GLY C CA  1 
ATOM 2089 C C   . GLY C 1 16  ? 275.275 263.882 404.062 1.00 58.32  ? 15  GLY C C   1 
ATOM 2090 O O   . GLY C 1 16  ? 274.546 264.312 404.961 1.00 58.32  ? 15  GLY C O   1 
ATOM 2091 N N   . LYS C 1 17  ? 276.525 264.307 403.895 1.00 58.56  ? 16  LYS C N   1 
ATOM 2092 C CA  . LYS C 1 17  ? 277.127 265.334 404.740 1.00 58.56  ? 16  LYS C CA  1 
ATOM 2093 C C   . LYS C 1 17  ? 277.919 266.325 403.899 1.00 58.56  ? 16  LYS C C   1 
ATOM 2094 O O   . LYS C 1 17  ? 279.032 266.716 404.257 1.00 58.56  ? 16  LYS C O   1 
ATOM 2095 C CB  . LYS C 1 17  ? 278.019 264.715 405.814 1.00 58.56  ? 16  LYS C CB  1 
ATOM 2096 C CG  . LYS C 1 17  ? 277.270 263.970 406.903 1.00 58.56  ? 16  LYS C CG  1 
ATOM 2097 C CD  . LYS C 1 17  ? 278.211 263.366 407.921 1.00 58.56  ? 16  LYS C CD  1 
ATOM 2098 C CE  . LYS C 1 17  ? 277.435 262.594 408.971 1.00 58.56  ? 16  LYS C CE  1 
ATOM 2099 N NZ  . LYS C 1 17  ? 278.338 261.954 409.965 1.00 58.56  ? 16  LYS C NZ  1 
ATOM 2100 N N   . GLN C 1 18  ? 277.364 266.738 402.764 1.00 55.36  ? 17  GLN C N   1 
ATOM 2101 C CA  . GLN C 1 18  ? 277.997 267.730 401.909 1.00 55.36  ? 17  GLN C CA  1 
ATOM 2102 C C   . GLN C 1 18  ? 276.979 268.793 401.534 1.00 55.36  ? 17  GLN C C   1 
ATOM 2103 O O   . GLN C 1 18  ? 275.768 268.583 401.629 1.00 55.36  ? 17  GLN C O   1 
ATOM 2104 C CB  . GLN C 1 18  ? 278.582 267.095 400.647 1.00 55.36  ? 17  GLN C CB  1 
ATOM 2105 C CG  . GLN C 1 18  ? 279.734 266.164 400.912 1.00 55.36  ? 17  GLN C CG  1 
ATOM 2106 C CD  . GLN C 1 18  ? 280.244 265.511 399.660 1.00 55.36  ? 17  GLN C CD  1 
ATOM 2107 O OE1 . GLN C 1 18  ? 279.708 265.721 398.576 1.00 55.36  ? 17  GLN C OE1 1 
ATOM 2108 N NE2 . GLN C 1 18  ? 281.287 264.708 399.797 1.00 55.36  ? 17  GLN C NE2 1 
ATOM 2109 N N   . THR C 1 19  ? 277.481 269.947 401.112 1.00 49.92  ? 18  THR C N   1 
ATOM 2110 C CA  . THR C 1 19  ? 276.648 271.082 400.752 1.00 49.92  ? 18  THR C CA  1 
ATOM 2111 C C   . THR C 1 19  ? 276.849 271.435 399.286 1.00 49.92  ? 18  THR C C   1 
ATOM 2112 O O   . THR C 1 19  ? 277.747 270.925 398.615 1.00 49.92  ? 18  THR C O   1 
ATOM 2113 C CB  . THR C 1 19  ? 276.960 272.304 401.622 1.00 49.92  ? 18  THR C CB  1 
ATOM 2114 O OG1 . THR C 1 19  ? 278.314 272.716 401.401 1.00 49.92  ? 18  THR C OG1 1 
ATOM 2115 C CG2 . THR C 1 19  ? 276.772 271.980 403.091 1.00 49.92  ? 18  THR C CG2 1 
ATOM 2116 N N   . LEU C 1 20  ? 275.985 272.318 398.792 1.00 44.64  ? 19  LEU C N   1 
ATOM 2117 C CA  . LEU C 1 20  ? 276.108 272.842 397.435 1.00 44.64  ? 19  LEU C CA  1 
ATOM 2118 C C   . LEU C 1 20  ? 275.447 274.210 397.423 1.00 44.64  ? 19  LEU C C   1 
ATOM 2119 O O   . LEU C 1 20  ? 274.219 274.297 397.438 1.00 44.64  ? 19  LEU C O   1 
ATOM 2120 C CB  . LEU C 1 20  ? 275.454 271.913 396.422 1.00 44.64  ? 19  LEU C CB  1 
ATOM 2121 C CG  . LEU C 1 20  ? 275.652 272.276 394.956 1.00 44.64  ? 19  LEU C CG  1 
ATOM 2122 C CD1 . LEU C 1 20  ? 277.089 272.084 394.568 1.00 44.64  ? 19  LEU C CD1 1 
ATOM 2123 C CD2 . LEU C 1 20  ? 274.742 271.460 394.075 1.00 44.64  ? 19  LEU C CD2 1 
ATOM 2124 N N   . VAL C 1 21  ? 276.246 275.269 397.405 1.00 41.34  ? 20  VAL C N   1 
ATOM 2125 C CA  . VAL C 1 21  ? 275.738 276.633 397.449 1.00 41.34  ? 20  VAL C CA  1 
ATOM 2126 C C   . VAL C 1 21  ? 275.685 277.172 396.030 1.00 41.34  ? 20  VAL C C   1 
ATOM 2127 O O   . VAL C 1 21  ? 276.719 277.313 395.371 1.00 41.34  ? 20  VAL C O   1 
ATOM 2128 C CB  . VAL C 1 21  ? 276.604 277.529 398.343 1.00 41.34  ? 20  VAL C CB  1 
ATOM 2129 C CG1 . VAL C 1 21  ? 276.069 278.938 398.318 1.00 41.34  ? 20  VAL C CG1 1 
ATOM 2130 C CG2 . VAL C 1 21  ? 276.620 277.001 399.753 1.00 41.34  ? 20  VAL C CG2 1 
ATOM 2131 N N   . LEU C 1 22  ? 274.481 277.480 395.564 1.00 37.94  ? 21  LEU C N   1 
ATOM 2132 C CA  . LEU C 1 22  ? 274.239 277.914 394.197 1.00 37.94  ? 21  LEU C CA  1 
ATOM 2133 C C   . LEU C 1 22  ? 273.878 279.391 394.189 1.00 37.94  ? 21  LEU C C   1 
ATOM 2134 O O   . LEU C 1 22  ? 272.983 279.814 394.922 1.00 37.94  ? 21  LEU C O   1 
ATOM 2135 C CB  . LEU C 1 22  ? 273.104 277.103 393.577 1.00 37.94  ? 21  LEU C CB  1 
ATOM 2136 C CG  . LEU C 1 22  ? 273.322 275.608 393.397 1.00 37.94  ? 21  LEU C CG  1 
ATOM 2137 C CD1 . LEU C 1 22  ? 272.012 274.916 393.127 1.00 37.94  ? 21  LEU C CD1 1 
ATOM 2138 C CD2 . LEU C 1 22  ? 274.281 275.353 392.258 1.00 37.94  ? 21  LEU C CD2 1 
ATOM 2139 N N   . ASN C 1 23  ? 274.558 280.160 393.370 1.00 38.15  ? 22  ASN C N   1 
ATOM 2140 C CA  . ASN C 1 23  ? 274.187 281.557 393.244 1.00 38.15  ? 22  ASN C CA  1 
ATOM 2141 C C   . ASN C 1 23  ? 273.400 281.772 391.957 1.00 38.15  ? 22  ASN C C   1 
ATOM 2142 O O   . ASN C 1 23  ? 273.552 281.003 391.007 1.00 38.15  ? 22  ASN C O   1 
ATOM 2143 C CB  . ASN C 1 23  ? 275.428 282.452 393.238 1.00 38.15  ? 22  ASN C CB  1 
ATOM 2144 C CG  . ASN C 1 23  ? 276.228 282.350 394.512 1.00 38.15  ? 22  ASN C CG  1 
ATOM 2145 O OD1 . ASN C 1 23  ? 277.387 281.952 394.495 1.00 38.15  ? 22  ASN C OD1 1 
ATOM 2146 N ND2 . ASN C 1 23  ? 275.612 282.691 395.627 1.00 38.15  ? 22  ASN C ND2 1 
ATOM 2147 N N   . PRO C 1 24  ? 272.529 282.777 391.879 1.00 36.78  ? 23  PRO C N   1 
ATOM 2148 C CA  . PRO C 1 24  ? 271.785 282.999 390.636 1.00 36.78  ? 23  PRO C CA  1 
ATOM 2149 C C   . PRO C 1 24  ? 272.652 283.579 389.536 1.00 36.78  ? 23  PRO C C   1 
ATOM 2150 O O   . PRO C 1 24  ? 273.648 284.257 389.786 1.00 36.78  ? 23  PRO C O   1 
ATOM 2151 C CB  . PRO C 1 24  ? 270.694 283.988 391.048 1.00 36.78  ? 23  PRO C CB  1 
ATOM 2152 C CG  . PRO C 1 24  ? 270.575 283.832 392.493 1.00 36.78  ? 23  PRO C CG  1 
ATOM 2153 C CD  . PRO C 1 24  ? 271.951 283.557 392.981 1.00 36.78  ? 23  PRO C CD  1 
ATOM 2154 N N   . ARG C 1 25  ? 272.262 283.286 388.295 1.00 34.73  ? 24  ARG C N   1 
ATOM 2155 C CA  . ARG C 1 25  ? 273.020 283.726 387.131 1.00 34.73  ? 24  ARG C CA  1 
ATOM 2156 C C   . ARG C 1 25  ? 272.125 284.264 386.021 1.00 34.73  ? 24  ARG C C   1 
ATOM 2157 O O   . ARG C 1 25  ? 272.457 284.101 384.843 1.00 34.73  ? 24  ARG C O   1 
ATOM 2158 C CB  . ARG C 1 25  ? 273.877 282.599 386.556 1.00 34.73  ? 24  ARG C CB  1 
ATOM 2159 C CG  . ARG C 1 25  ? 275.012 282.135 387.426 1.00 34.73  ? 24  ARG C CG  1 
ATOM 2160 C CD  . ARG C 1 25  ? 276.025 283.225 387.610 1.00 34.73  ? 24  ARG C CD  1 
ATOM 2161 N NE  . ARG C 1 25  ? 277.170 282.789 388.394 1.00 34.73  ? 24  ARG C NE  1 
ATOM 2162 C CZ  . ARG C 1 25  ? 278.315 282.376 387.873 1.00 34.73  ? 24  ARG C CZ  1 
ATOM 2163 N NH1 . ARG C 1 25  ? 278.474 282.352 386.559 1.00 34.73  ? 24  ARG C NH1 1 
ATOM 2164 N NH2 . ARG C 1 25  ? 279.306 282.001 388.666 1.00 34.73  ? 24  ARG C NH2 1 
ATOM 2165 N N   . GLY C 1 26  ? 271.000 284.879 386.356 1.00 33.78  ? 25  GLY C N   1 
ATOM 2166 C CA  . GLY C 1 26  ? 270.218 285.617 385.390 1.00 33.78  ? 25  GLY C CA  1 
ATOM 2167 C C   . GLY C 1 26  ? 269.359 284.743 384.493 1.00 33.78  ? 25  GLY C C   1 
ATOM 2168 O O   . GLY C 1 26  ? 269.595 283.554 384.308 1.00 33.78  ? 25  GLY C O   1 
ATOM 2169 N N   . VAL C 1 27  ? 268.346 285.371 383.916 1.00 31.97  ? 26  VAL C N   1 
ATOM 2170 C CA  . VAL C 1 27  ? 267.401 284.703 383.033 1.00 31.97  ? 26  VAL C CA  1 
ATOM 2171 C C   . VAL C 1 27  ? 267.847 284.900 381.592 1.00 31.97  ? 26  VAL C C   1 
ATOM 2172 O O   . VAL C 1 27  ? 268.173 286.018 381.184 1.00 31.97  ? 26  VAL C O   1 
ATOM 2173 C CB  . VAL C 1 27  ? 265.981 285.249 383.251 1.00 31.97  ? 26  VAL C CB  1 
ATOM 2174 C CG1 . VAL C 1 27  ? 264.998 284.610 382.306 1.00 31.97  ? 26  VAL C CG1 1 
ATOM 2175 C CG2 . VAL C 1 27  ? 265.551 285.035 384.684 1.00 31.97  ? 26  VAL C CG2 1 
ATOM 2176 N N   . ASN C 1 28  ? 267.882 283.816 380.832 1.00 34.85  ? 27  ASN C N   1 
ATOM 2177 C CA  . ASN C 1 28  ? 268.127 283.888 379.398 1.00 34.85  ? 27  ASN C CA  1 
ATOM 2178 C C   . ASN C 1 28  ? 266.911 284.510 378.725 1.00 34.85  ? 27  ASN C C   1 
ATOM 2179 O O   . ASN C 1 28  ? 265.819 283.944 378.812 1.00 34.85  ? 27  ASN C O   1 
ATOM 2180 C CB  . ASN C 1 28  ? 268.393 282.485 378.867 1.00 34.85  ? 27  ASN C CB  1 
ATOM 2181 C CG  . ASN C 1 28  ? 268.978 282.475 377.470 1.00 34.85  ? 27  ASN C CG  1 
ATOM 2182 O OD1 . ASN C 1 28  ? 269.171 283.514 376.848 1.00 34.85  ? 27  ASN C OD1 1 
ATOM 2183 N ND2 . ASN C 1 28  ? 269.271 281.284 376.972 1.00 34.85  ? 27  ASN C ND2 1 
ATOM 2184 N N   . PRO C 1 29  ? 267.045 285.659 378.054 1.00 37.71  ? 28  PRO C N   1 
ATOM 2185 C CA  . PRO C 1 29  ? 265.850 286.384 377.598 1.00 37.71  ? 28  PRO C CA  1 
ATOM 2186 C C   . PRO C 1 29  ? 265.150 285.769 376.403 1.00 37.71  ? 28  PRO C C   1 
ATOM 2187 O O   . PRO C 1 29  ? 263.994 286.124 376.142 1.00 37.71  ? 28  PRO C O   1 
ATOM 2188 C CB  . PRO C 1 29  ? 266.400 287.769 377.233 1.00 37.71  ? 28  PRO C CB  1 
ATOM 2189 C CG  . PRO C 1 29  ? 267.716 287.860 377.916 1.00 37.71  ? 28  PRO C CG  1 
ATOM 2190 C CD  . PRO C 1 29  ? 268.258 286.475 377.900 1.00 37.71  ? 28  PRO C CD  1 
ATOM 2191 N N   . THR C 1 30  ? 265.799 284.869 375.668 1.00 38.11  ? 29  THR C N   1 
ATOM 2192 C CA  . THR C 1 30  ? 265.190 284.332 374.457 1.00 38.11  ? 29  THR C CA  1 
ATOM 2193 C C   . THR C 1 30  ? 264.245 283.178 374.765 1.00 38.11  ? 29  THR C C   1 
ATOM 2194 O O   . THR C 1 30  ? 263.118 283.142 374.260 1.00 38.11  ? 29  THR C O   1 
ATOM 2195 C CB  . THR C 1 30  ? 266.275 283.889 373.478 1.00 38.11  ? 29  THR C CB  1 
ATOM 2196 O OG1 . THR C 1 30  ? 267.064 282.855 374.074 1.00 38.11  ? 29  THR C OG1 1 
ATOM 2197 C CG2 . THR C 1 30  ? 267.173 285.058 373.137 1.00 38.11  ? 29  THR C CG2 1 
ATOM 2198 N N   . ASN C 1 31  ? 264.683 282.226 375.587 1.00 36.55  ? 30  ASN C N   1 
ATOM 2199 C CA  . ASN C 1 31  ? 263.876 281.060 375.908 1.00 36.55  ? 30  ASN C CA  1 
ATOM 2200 C C   . ASN C 1 31  ? 263.363 281.030 377.340 1.00 36.55  ? 30  ASN C C   1 
ATOM 2201 O O   . ASN C 1 31  ? 262.515 280.190 377.652 1.00 36.55  ? 30  ASN C O   1 
ATOM 2202 C CB  . ASN C 1 31  ? 264.662 279.774 375.612 1.00 36.55  ? 30  ASN C CB  1 
ATOM 2203 C CG  . ASN C 1 31  ? 266.014 279.743 376.284 1.00 36.55  ? 30  ASN C CG  1 
ATOM 2204 O OD1 . ASN C 1 31  ? 266.381 280.654 377.016 1.00 36.55  ? 30  ASN C OD1 1 
ATOM 2205 N ND2 . ASN C 1 31  ? 266.766 278.679 376.042 1.00 36.55  ? 30  ASN C ND2 1 
ATOM 2206 N N   . GLY C 1 32  ? 263.842 281.905 378.214 1.00 34.80  ? 31  GLY C N   1 
ATOM 2207 C CA  . GLY C 1 32  ? 263.310 281.986 379.556 1.00 34.80  ? 31  GLY C CA  1 
ATOM 2208 C C   . GLY C 1 32  ? 263.964 281.082 380.570 1.00 34.80  ? 31  GLY C C   1 
ATOM 2209 O O   . GLY C 1 32  ? 263.458 280.976 381.691 1.00 34.80  ? 31  GLY C O   1 
ATOM 2210 N N   . VAL C 1 33  ? 265.072 280.441 380.223 1.00 32.17  ? 32  VAL C N   1 
ATOM 2211 C CA  . VAL C 1 33  ? 265.728 279.486 381.108 1.00 32.17  ? 32  VAL C CA  1 
ATOM 2212 C C   . VAL C 1 33  ? 266.537 280.236 382.154 1.00 32.17  ? 32  VAL C C   1 
ATOM 2213 O O   . VAL C 1 33  ? 267.401 281.051 381.818 1.00 32.17  ? 32  VAL C O   1 
ATOM 2214 C CB  . VAL C 1 33  ? 266.618 278.538 380.296 1.00 32.17  ? 32  VAL C CB  1 
ATOM 2215 C CG1 . VAL C 1 33  ? 267.385 277.634 381.208 1.00 32.17  ? 32  VAL C CG1 1 
ATOM 2216 C CG2 . VAL C 1 33  ? 265.777 277.734 379.338 1.00 32.17  ? 32  VAL C CG2 1 
ATOM 2217 N N   . ALA C 1 34  ? 266.265 279.961 383.426 1.00 30.62  ? 33  ALA C N   1 
ATOM 2218 C CA  . ALA C 1 34  ? 266.896 280.664 384.534 1.00 30.62  ? 33  ALA C CA  1 
ATOM 2219 C C   . ALA C 1 34  ? 267.997 279.797 385.125 1.00 30.62  ? 33  ALA C C   1 
ATOM 2220 O O   . ALA C 1 34  ? 267.755 278.643 385.484 1.00 30.62  ? 33  ALA C O   1 
ATOM 2221 C CB  . ALA C 1 34  ? 265.874 281.021 385.610 1.00 30.62  ? 33  ALA C CB  1 
ATOM 2222 N N   . SER C 1 35  ? 269.194 280.356 385.235 1.00 32.37  ? 34  SER C N   1 
ATOM 2223 C CA  . SER C 1 35  ? 270.377 279.588 385.579 1.00 32.37  ? 34  SER C CA  1 
ATOM 2224 C C   . SER C 1 35  ? 270.758 279.770 387.040 1.00 32.37  ? 34  SER C C   1 
ATOM 2225 O O   . SER C 1 35  ? 270.510 280.814 387.644 1.00 32.37  ? 34  SER C O   1 
ATOM 2226 C CB  . SER C 1 35  ? 271.556 279.982 384.697 1.00 32.37  ? 34  SER C CB  1 
ATOM 2227 O OG  . SER C 1 35  ? 271.289 279.693 383.341 1.00 32.37  ? 34  SER C OG  1 
ATOM 2228 N N   . LEU C 1 36  ? 271.367 278.732 387.598 1.00 32.98  ? 35  LEU C N   1 
ATOM 2229 C CA  . LEU C 1 36  ? 272.026 278.792 388.890 1.00 32.98  ? 35  LEU C CA  1 
ATOM 2230 C C   . LEU C 1 36  ? 273.402 278.172 388.727 1.00 32.98  ? 35  LEU C C   1 
ATOM 2231 O O   . LEU C 1 36  ? 273.592 277.275 387.905 1.00 32.98  ? 35  LEU C O   1 
ATOM 2232 C CB  . LEU C 1 36  ? 271.245 278.047 389.963 1.00 32.98  ? 35  LEU C CB  1 
ATOM 2233 C CG  . LEU C 1 36  ? 269.830 278.493 390.303 1.00 32.98  ? 35  LEU C CG  1 
ATOM 2234 C CD1 . LEU C 1 36  ? 269.209 277.488 391.231 1.00 32.98  ? 35  LEU C CD1 1 
ATOM 2235 C CD2 . LEU C 1 36  ? 269.826 279.843 390.944 1.00 32.98  ? 35  LEU C CD2 1 
ATOM 2236 N N   . SER C 1 37  ? 274.364 278.643 389.509 1.00 37.16  ? 36  SER C N   1 
ATOM 2237 C CA  . SER C 1 37  ? 275.715 278.122 389.396 1.00 37.16  ? 36  SER C CA  1 
ATOM 2238 C C   . SER C 1 37  ? 276.422 278.224 390.733 1.00 37.16  ? 36  SER C C   1 
ATOM 2239 O O   . SER C 1 37  ? 276.100 279.078 391.558 1.00 37.16  ? 36  SER C O   1 
ATOM 2240 C CB  . SER C 1 37  ? 276.520 278.857 388.330 1.00 37.16  ? 36  SER C CB  1 
ATOM 2241 O OG  . SER C 1 37  ? 277.851 278.391 388.306 1.00 37.16  ? 36  SER C OG  1 
ATOM 2242 N N   . GLN C 1 38  ? 277.389 277.336 390.935 1.00 40.78  ? 37  GLN C N   1 
ATOM 2243 C CA  . GLN C 1 38  ? 278.139 277.287 392.180 1.00 40.78  ? 37  GLN C CA  1 
ATOM 2244 C C   . GLN C 1 38  ? 279.327 278.237 392.112 1.00 40.78  ? 37  GLN C C   1 
ATOM 2245 O O   . GLN C 1 38  ? 279.976 278.363 391.072 1.00 40.78  ? 37  GLN C O   1 
ATOM 2246 C CB  . GLN C 1 38  ? 278.634 275.871 392.459 1.00 40.78  ? 37  GLN C CB  1 
ATOM 2247 C CG  . GLN C 1 38  ? 279.186 275.706 393.854 1.00 40.78  ? 37  GLN C CG  1 
ATOM 2248 C CD  . GLN C 1 38  ? 279.782 274.358 394.106 1.00 40.78  ? 37  GLN C CD  1 
ATOM 2249 O OE1 . GLN C 1 38  ? 279.926 273.552 393.195 1.00 40.78  ? 37  GLN C OE1 1 
ATOM 2250 N NE2 . GLN C 1 38  ? 280.110 274.088 395.358 1.00 40.78  ? 37  GLN C NE2 1 
ATOM 2251 N N   . ALA C 1 39  ? 279.617 278.892 393.232 1.00 45.29  ? 38  ALA C N   1 
ATOM 2252 C CA  . ALA C 1 39  ? 280.759 279.795 393.325 1.00 45.29  ? 38  ALA C CA  1 
ATOM 2253 C C   . ALA C 1 39  ? 282.031 278.963 393.377 1.00 45.29  ? 38  ALA C C   1 
ATOM 2254 O O   . ALA C 1 39  ? 282.556 278.668 394.451 1.00 45.29  ? 38  ALA C O   1 
ATOM 2255 C CB  . ALA C 1 39  ? 280.637 280.692 394.549 1.00 45.29  ? 38  ALA C CB  1 
ATOM 2256 N N   . GLY C 1 40  ? 282.526 278.574 392.209 1.00 46.43  ? 39  GLY C N   1 
ATOM 2257 C CA  . GLY C 1 40  ? 283.811 277.919 392.112 1.00 46.43  ? 39  GLY C CA  1 
ATOM 2258 C C   . GLY C 1 40  ? 284.667 278.629 391.090 1.00 46.43  ? 39  GLY C C   1 
ATOM 2259 O O   . GLY C 1 40  ? 284.154 279.059 390.054 1.00 46.43  ? 39  GLY C O   1 
ATOM 2260 N N   . ALA C 1 41  ? 285.963 278.770 391.365 1.00 48.40  ? 40  ALA C N   1 
ATOM 2261 C CA  . ALA C 1 41  ? 286.852 279.458 390.438 1.00 48.40  ? 40  ALA C CA  1 
ATOM 2262 C C   . ALA C 1 41  ? 287.075 278.612 389.191 1.00 48.40  ? 40  ALA C C   1 
ATOM 2263 O O   . ALA C 1 41  ? 286.767 277.415 389.188 1.00 48.40  ? 40  ALA C O   1 
ATOM 2264 C CB  . ALA C 1 41  ? 288.185 279.774 391.112 1.00 48.40  ? 40  ALA C CB  1 
ATOM 2265 N N   . VAL C 1 42  ? 287.653 279.236 388.164 1.00 44.98  ? 41  VAL C N   1 
ATOM 2266 C CA  . VAL C 1 42  ? 287.745 278.722 386.796 1.00 44.98  ? 41  VAL C CA  1 
ATOM 2267 C C   . VAL C 1 42  ? 286.337 278.372 386.319 1.00 44.98  ? 41  VAL C C   1 
ATOM 2268 O O   . VAL C 1 42  ? 285.912 277.216 386.447 1.00 44.98  ? 41  VAL C O   1 
ATOM 2269 C CB  . VAL C 1 42  ? 288.729 277.546 386.685 1.00 44.98  ? 41  VAL C CB  1 
ATOM 2270 C CG1 . VAL C 1 42  ? 288.930 277.146 385.234 1.00 44.98  ? 41  VAL C CG1 1 
ATOM 2271 C CG2 . VAL C 1 42  ? 290.039 277.917 387.324 1.00 44.98  ? 41  VAL C CG2 1 
ATOM 2272 N N   . PRO C 1 43  ? 285.556 279.353 385.838 1.00 41.08  ? 42  PRO C N   1 
ATOM 2273 C CA  . PRO C 1 43  ? 284.139 279.102 385.506 1.00 41.08  ? 42  PRO C CA  1 
ATOM 2274 C C   . PRO C 1 43  ? 283.875 278.100 384.384 1.00 41.08  ? 42  PRO C C   1 
ATOM 2275 O O   . PRO C 1 43  ? 282.705 277.892 384.050 1.00 41.08  ? 42  PRO C O   1 
ATOM 2276 C CB  . PRO C 1 43  ? 283.632 280.490 385.100 1.00 41.08  ? 42  PRO C CB  1 
ATOM 2277 C CG  . PRO C 1 43  ? 284.573 281.433 385.699 1.00 41.08  ? 42  PRO C CG  1 
ATOM 2278 C CD  . PRO C 1 43  ? 285.899 280.774 385.682 1.00 41.08  ? 42  PRO C CD  1 
ATOM 2279 N N   . ALA C 1 44  ? 284.894 277.488 383.780 1.00 42.35  ? 43  ALA C N   1 
ATOM 2280 C CA  . ALA C 1 44  ? 284.642 276.375 382.875 1.00 42.35  ? 43  ALA C CA  1 
ATOM 2281 C C   . ALA C 1 44  ? 284.165 275.150 383.636 1.00 42.35  ? 43  ALA C C   1 
ATOM 2282 O O   . ALA C 1 44  ? 283.475 274.293 383.077 1.00 42.35  ? 43  ALA C O   1 
ATOM 2283 C CB  . ALA C 1 44  ? 285.898 276.043 382.078 1.00 42.35  ? 43  ALA C CB  1 
ATOM 2284 N N   . LEU C 1 45  ? 284.531 275.043 384.907 1.00 43.72  ? 44  LEU C N   1 
ATOM 2285 C CA  . LEU C 1 45  ? 284.173 273.893 385.726 1.00 43.72  ? 44  LEU C CA  1 
ATOM 2286 C C   . LEU C 1 45  ? 283.411 274.376 386.958 1.00 43.72  ? 44  LEU C C   1 
ATOM 2287 O O   . LEU C 1 45  ? 283.995 274.729 387.981 1.00 43.72  ? 44  LEU C O   1 
ATOM 2288 C CB  . LEU C 1 45  ? 285.422 273.070 386.038 1.00 43.72  ? 44  LEU C CB  1 
ATOM 2289 C CG  . LEU C 1 45  ? 286.734 273.568 386.657 1.00 43.72  ? 44  LEU C CG  1 
ATOM 2290 C CD1 . LEU C 1 45  ? 286.864 273.272 388.141 1.00 43.72  ? 44  LEU C CD1 1 
ATOM 2291 C CD2 . LEU C 1 45  ? 287.914 273.023 385.888 1.00 43.72  ? 44  LEU C CD2 1 
ATOM 2292 N N   . GLU C 1 46  ? 282.088 274.405 386.845 1.00 40.97  ? 45  GLU C N   1 
ATOM 2293 C CA  . GLU C 1 46  ? 281.218 274.748 387.957 1.00 40.97  ? 45  GLU C CA  1 
ATOM 2294 C C   . GLU C 1 46  ? 280.020 273.815 387.951 1.00 40.97  ? 45  GLU C C   1 
ATOM 2295 O O   . GLU C 1 46  ? 279.601 273.343 386.894 1.00 40.97  ? 45  GLU C O   1 
ATOM 2296 C CB  . GLU C 1 46  ? 280.722 276.189 387.868 1.00 40.97  ? 45  GLU C CB  1 
ATOM 2297 C CG  . GLU C 1 46  ? 281.741 277.256 388.133 1.00 40.97  ? 45  GLU C CG  1 
ATOM 2298 C CD  . GLU C 1 46  ? 281.161 278.636 387.938 1.00 40.97  ? 45  GLU C CD  1 
ATOM 2299 O OE1 . GLU C 1 46  ? 280.031 278.729 387.416 1.00 40.97  ? 45  GLU C OE1 1 
ATOM 2300 O OE2 . GLU C 1 46  ? 281.822 279.625 388.313 1.00 40.97  ? 45  GLU C OE2 1 
ATOM 2301 N N   . LYS C 1 47  ? 279.481 273.556 389.133 1.00 37.79  ? 46  LYS C N   1 
ATOM 2302 C CA  . LYS C 1 47  ? 278.193 272.894 389.243 1.00 37.79  ? 46  LYS C CA  1 
ATOM 2303 C C   . LYS C 1 47  ? 277.110 273.840 388.732 1.00 37.79  ? 46  LYS C C   1 
ATOM 2304 O O   . LYS C 1 47  ? 276.986 274.960 389.229 1.00 37.79  ? 46  LYS C O   1 
ATOM 2305 C CB  . LYS C 1 47  ? 277.939 272.517 390.702 1.00 37.79  ? 46  LYS C CB  1 
ATOM 2306 C CG  . LYS C 1 47  ? 278.385 271.127 391.157 1.00 37.79  ? 46  LYS C CG  1 
ATOM 2307 C CD  . LYS C 1 47  ? 279.869 270.870 391.036 1.00 37.79  ? 46  LYS C CD  1 
ATOM 2308 C CE  . LYS C 1 47  ? 280.207 269.463 391.476 1.00 37.79  ? 46  LYS C CE  1 
ATOM 2309 N NZ  . LYS C 1 47  ? 279.860 269.265 392.903 1.00 37.79  ? 46  LYS C NZ  1 
ATOM 2310 N N   . ARG C 1 48  ? 276.335 273.409 387.736 1.00 35.82  ? 47  ARG C N   1 
ATOM 2311 C CA  . ARG C 1 48  ? 275.365 274.281 387.076 1.00 35.82  ? 47  ARG C CA  1 
ATOM 2312 C C   . ARG C 1 48  ? 273.982 273.648 387.082 1.00 35.82  ? 47  ARG C C   1 
ATOM 2313 O O   . ARG C 1 48  ? 273.835 272.479 386.723 1.00 35.82  ? 47  ARG C O   1 
ATOM 2314 C CB  . ARG C 1 48  ? 275.774 274.575 385.637 1.00 35.82  ? 47  ARG C CB  1 
ATOM 2315 C CG  . ARG C 1 48  ? 276.975 275.461 385.502 1.00 35.82  ? 47  ARG C CG  1 
ATOM 2316 C CD  . ARG C 1 48  ? 277.292 275.686 384.046 1.00 35.82  ? 47  ARG C CD  1 
ATOM 2317 N NE  . ARG C 1 48  ? 278.467 276.527 383.878 1.00 35.82  ? 47  ARG C NE  1 
ATOM 2318 C CZ  . ARG C 1 48  ? 279.014 276.806 382.703 1.00 35.82  ? 47  ARG C CZ  1 
ATOM 2319 N NH1 . ARG C 1 48  ? 278.493 276.299 381.595 1.00 35.82  ? 47  ARG C NH1 1 
ATOM 2320 N NH2 . ARG C 1 48  ? 280.084 277.583 382.636 1.00 35.82  ? 47  ARG C NH2 1 
ATOM 2321 N N   . VAL C 1 49  ? 272.972 274.423 387.482 1.00 30.09  ? 48  VAL C N   1 
ATOM 2322 C CA  . VAL C 1 49  ? 271.580 273.982 387.538 1.00 30.09  ? 48  VAL C CA  1 
ATOM 2323 C C   . VAL C 1 49  ? 270.732 275.020 386.822 1.00 30.09  ? 48  VAL C C   1 
ATOM 2324 O O   . VAL C 1 49  ? 270.823 276.210 387.132 1.00 30.09  ? 48  VAL C O   1 
ATOM 2325 C CB  . VAL C 1 49  ? 271.081 273.821 388.988 1.00 30.09  ? 48  VAL C CB  1 
ATOM 2326 C CG1 . VAL C 1 49  ? 269.645 273.371 389.011 1.00 30.09  ? 48  VAL C CG1 1 
ATOM 2327 C CG2 . VAL C 1 49  ? 271.944 272.868 389.768 1.00 30.09  ? 48  VAL C CG2 1 
ATOM 2328 N N   . THR C 1 50  ? 269.912 274.588 385.867 1.00 28.82  ? 49  THR C N   1 
ATOM 2329 C CA  . THR C 1 50  ? 268.980 275.494 385.210 1.00 28.82  ? 49  THR C CA  1 
ATOM 2330 C C   . THR C 1 50  ? 267.552 275.003 385.396 1.00 28.82  ? 49  THR C C   1 
ATOM 2331 O O   . THR C 1 50  ? 267.312 273.810 385.577 1.00 28.82  ? 49  THR C O   1 
ATOM 2332 C CB  . THR C 1 50  ? 269.258 275.632 383.715 1.00 28.82  ? 49  THR C CB  1 
ATOM 2333 O OG1 . THR C 1 50  ? 268.979 274.393 383.064 1.00 28.82  ? 49  THR C OG1 1 
ATOM 2334 C CG2 . THR C 1 50  ? 270.701 276.000 383.460 1.00 28.82  ? 49  THR C CG2 1 
ATOM 2335 N N   . VAL C 1 51  ? 266.603 275.935 385.344 1.00 29.05  ? 50  VAL C N   1 
ATOM 2336 C CA  . VAL C 1 51  ? 265.185 275.639 385.499 1.00 29.05  ? 50  VAL C CA  1 
ATOM 2337 C C   . VAL C 1 51  ? 264.403 276.414 384.440 1.00 29.05  ? 50  VAL C C   1 
ATOM 2338 O O   . VAL C 1 51  ? 264.734 277.561 384.127 1.00 29.05  ? 50  VAL C O   1 
ATOM 2339 C CB  . VAL C 1 51  ? 264.716 275.946 386.942 1.00 29.05  ? 50  VAL C CB  1 
ATOM 2340 C CG1 . VAL C 1 51  ? 265.004 277.377 387.334 1.00 29.05  ? 50  VAL C CG1 1 
ATOM 2341 C CG2 . VAL C 1 51  ? 263.249 275.651 387.134 1.00 29.05  ? 50  VAL C CG2 1 
ATOM 2342 N N   . SER C 1 52  ? 263.405 275.768 383.843 1.00 30.22  ? 51  SER C N   1 
ATOM 2343 C CA  . SER C 1 52  ? 262.662 276.342 382.726 1.00 30.22  ? 51  SER C CA  1 
ATOM 2344 C C   . SER C 1 52  ? 261.190 276.000 382.857 1.00 30.22  ? 51  SER C C   1 
ATOM 2345 O O   . SER C 1 52  ? 260.829 274.823 382.873 1.00 30.22  ? 51  SER C O   1 
ATOM 2346 C CB  . SER C 1 52  ? 263.202 275.827 381.396 1.00 30.22  ? 51  SER C CB  1 
ATOM 2347 O OG  . SER C 1 52  ? 262.417 276.294 380.319 1.00 30.22  ? 51  SER C OG  1 
ATOM 2348 N N   . VAL C 1 53  ? 260.340 277.021 382.935 1.00 35.26  ? 52  VAL C N   1 
ATOM 2349 C CA  . VAL C 1 53  ? 258.896 276.853 383.051 1.00 35.26  ? 52  VAL C CA  1 
ATOM 2350 C C   . VAL C 1 53  ? 258.236 277.596 381.901 1.00 35.26  ? 52  VAL C C   1 
ATOM 2351 O O   . VAL C 1 53  ? 258.627 278.723 381.583 1.00 35.26  ? 52  VAL C O   1 
ATOM 2352 C CB  . VAL C 1 53  ? 258.375 277.371 384.408 1.00 35.26  ? 52  VAL C CB  1 
ATOM 2353 C CG1 . VAL C 1 53  ? 256.883 277.187 384.529 1.00 35.26  ? 52  VAL C CG1 1 
ATOM 2354 C CG2 . VAL C 1 53  ? 259.071 276.691 385.556 1.00 35.26  ? 52  VAL C CG2 1 
ATOM 2355 N N   . SER C 1 54  ? 257.255 276.958 381.263 1.00 43.99  ? 53  SER C N   1 
ATOM 2356 C CA  . SER C 1 54  ? 256.471 277.619 380.229 1.00 43.99  ? 53  SER C CA  1 
ATOM 2357 C C   . SER C 1 54  ? 255.651 278.760 380.816 1.00 43.99  ? 53  SER C C   1 
ATOM 2358 O O   . SER C 1 54  ? 255.165 278.691 381.947 1.00 43.99  ? 53  SER C O   1 
ATOM 2359 C CB  . SER C 1 54  ? 255.550 276.625 379.535 1.00 43.99  ? 53  SER C CB  1 
ATOM 2360 O OG  . SER C 1 54  ? 256.297 275.693 378.786 1.00 43.99  ? 53  SER C OG  1 
ATOM 2361 N N   . GLN C 1 55  ? 255.501 279.817 380.032 1.00 52.54  ? 54  GLN C N   1 
ATOM 2362 C CA  . GLN C 1 55  ? 254.876 281.033 380.527 1.00 52.54  ? 54  GLN C CA  1 
ATOM 2363 C C   . GLN C 1 55  ? 253.362 280.864 380.598 1.00 52.54  ? 54  GLN C C   1 
ATOM 2364 O O   . GLN C 1 55  ? 252.772 280.203 379.740 1.00 52.54  ? 54  GLN C O   1 
ATOM 2365 C CB  . GLN C 1 55  ? 255.223 282.217 379.636 1.00 52.54  ? 54  GLN C CB  1 
ATOM 2366 C CG  . GLN C 1 55  ? 256.681 282.607 379.679 1.00 52.54  ? 54  GLN C CG  1 
ATOM 2367 C CD  . GLN C 1 55  ? 257.129 282.966 381.075 1.00 52.54  ? 54  GLN C CD  1 
ATOM 2368 O OE1 . GLN C 1 55  ? 257.982 282.299 381.657 1.00 52.54  ? 54  GLN C OE1 1 
ATOM 2369 N NE2 . GLN C 1 55  ? 256.524 284.002 381.638 1.00 52.54  ? 54  GLN C NE2 1 
ATOM 2370 N N   . PRO C 1 56  ? 252.716 281.439 381.614 1.00 57.11  ? 55  PRO C N   1 
ATOM 2371 C CA  . PRO C 1 56  ? 251.255 281.350 381.698 1.00 57.11  ? 55  PRO C CA  1 
ATOM 2372 C C   . PRO C 1 56  ? 250.561 282.202 380.652 1.00 57.11  ? 55  PRO C C   1 
ATOM 2373 O O   . PRO C 1 56  ? 250.523 283.432 380.746 1.00 57.11  ? 55  PRO C O   1 
ATOM 2374 C CB  . PRO C 1 56  ? 250.953 281.838 383.120 1.00 57.11  ? 55  PRO C CB  1 
ATOM 2375 C CG  . PRO C 1 56  ? 252.115 282.689 383.485 1.00 57.11  ? 55  PRO C CG  1 
ATOM 2376 C CD  . PRO C 1 56  ? 253.300 282.090 382.800 1.00 57.11  ? 55  PRO C CD  1 
ATOM 2377 N N   . SER C 1 57  ? 250.011 281.543 379.641 1.00 63.35  ? 56  SER C N   1 
ATOM 2378 C CA  . SER C 1 57  ? 249.214 282.198 378.621 1.00 63.35  ? 56  SER C CA  1 
ATOM 2379 C C   . SER C 1 57  ? 247.769 281.742 378.756 1.00 63.35  ? 56  SER C C   1 
ATOM 2380 O O   . SER C 1 57  ? 247.460 280.783 379.468 1.00 63.35  ? 56  SER C O   1 
ATOM 2381 C CB  . SER C 1 57  ? 249.738 281.890 377.214 1.00 63.35  ? 56  SER C CB  1 
ATOM 2382 O OG  . SER C 1 57  ? 248.928 282.500 376.227 1.00 63.35  ? 56  SER C OG  1 
ATOM 2383 N N   . ARG C 1 58  ? 246.878 282.452 378.068 1.00 69.95  ? 57  ARG C N   1 
ATOM 2384 C CA  . ARG C 1 58  ? 245.461 282.117 378.140 1.00 69.95  ? 57  ARG C CA  1 
ATOM 2385 C C   . ARG C 1 58  ? 245.145 280.877 377.314 1.00 69.95  ? 57  ARG C C   1 
ATOM 2386 O O   . ARG C 1 58  ? 244.350 280.027 377.736 1.00 69.95  ? 57  ARG C O   1 
ATOM 2387 C CB  . ARG C 1 58  ? 244.626 283.308 377.676 1.00 69.95  ? 57  ARG C CB  1 
ATOM 2388 C CG  . ARG C 1 58  ? 243.125 283.115 377.776 1.00 69.95  ? 57  ARG C CG  1 
ATOM 2389 C CD  . ARG C 1 58  ? 242.413 284.370 377.321 1.00 69.95  ? 57  ARG C CD  1 
ATOM 2390 N NE  . ARG C 1 58  ? 242.667 284.648 375.912 1.00 69.95  ? 57  ARG C NE  1 
ATOM 2391 C CZ  . ARG C 1 58  ? 242.341 285.781 375.303 1.00 69.95  ? 57  ARG C CZ  1 
ATOM 2392 N NH1 . ARG C 1 58  ? 241.745 286.751 375.981 1.00 69.95  ? 57  ARG C NH1 1 
ATOM 2393 N NH2 . ARG C 1 58  ? 242.614 285.946 374.016 1.00 69.95  ? 57  ARG C NH2 1 
ATOM 2394 N N   . ASN C 1 59  ? 245.767 280.746 376.146 1.00 67.71  ? 58  ASN C N   1 
ATOM 2395 C CA  . ASN C 1 59  ? 245.491 279.654 375.222 1.00 67.71  ? 58  ASN C CA  1 
ATOM 2396 C C   . ASN C 1 59  ? 246.613 278.616 375.184 1.00 67.71  ? 58  ASN C C   1 
ATOM 2397 O O   . ASN C 1 59  ? 246.920 278.065 374.124 1.00 67.71  ? 58  ASN C O   1 
ATOM 2398 C CB  . ASN C 1 59  ? 245.206 280.212 373.828 1.00 67.71  ? 58  ASN C CB  1 
ATOM 2399 C CG  . ASN C 1 59  ? 246.295 281.153 373.329 1.00 67.71  ? 58  ASN C CG  1 
ATOM 2400 O OD1 . ASN C 1 59  ? 247.321 281.349 373.980 1.00 67.71  ? 58  ASN C OD1 1 
ATOM 2401 N ND2 . ASN C 1 59  ? 246.065 281.750 372.164 1.00 67.71  ? 58  ASN C ND2 1 
ATOM 2402 N N   . ARG C 1 60  ? 247.232 278.341 376.331 1.00 55.50  ? 59  ARG C N   1 
ATOM 2403 C CA  . ARG C 1 60  ? 248.256 277.308 376.437 1.00 55.50  ? 59  ARG C CA  1 
ATOM 2404 C C   . ARG C 1 60  ? 247.628 276.007 376.915 1.00 55.50  ? 59  ARG C C   1 
ATOM 2405 O O   . ARG C 1 60  ? 246.882 275.996 377.897 1.00 55.50  ? 59  ARG C O   1 
ATOM 2406 C CB  . ARG C 1 60  ? 249.368 277.737 377.393 1.00 55.50  ? 59  ARG C CB  1 
ATOM 2407 C CG  . ARG C 1 60  ? 250.507 276.752 377.478 1.00 55.50  ? 59  ARG C CG  1 
ATOM 2408 C CD  . ARG C 1 60  ? 251.620 277.250 378.368 1.00 55.50  ? 59  ARG C CD  1 
ATOM 2409 N NE  . ARG C 1 60  ? 252.255 278.439 377.813 1.00 55.50  ? 59  ARG C NE  1 
ATOM 2410 C CZ  . ARG C 1 60  ? 253.207 278.415 376.887 1.00 55.50  ? 59  ARG C CZ  1 
ATOM 2411 N NH1 . ARG C 1 60  ? 253.726 279.550 376.441 1.00 55.50  ? 59  ARG C NH1 1 
ATOM 2412 N NH2 . ARG C 1 60  ? 253.637 277.260 376.399 1.00 55.50  ? 59  ARG C NH2 1 
ATOM 2413 N N   . LYS C 1 61  ? 247.937 274.912 376.224 1.00 53.22  ? 60  LYS C N   1 
ATOM 2414 C CA  . LYS C 1 61  ? 247.318 273.630 376.528 1.00 53.22  ? 60  LYS C CA  1 
ATOM 2415 C C   . LYS C 1 61  ? 248.147 272.767 377.466 1.00 53.22  ? 60  LYS C C   1 
ATOM 2416 O O   . LYS C 1 61  ? 247.577 271.973 378.219 1.00 53.22  ? 60  LYS C O   1 
ATOM 2417 C CB  . LYS C 1 61  ? 247.054 272.858 375.236 1.00 53.22  ? 60  LYS C CB  1 
ATOM 2418 C CG  . LYS C 1 61  ? 246.111 273.566 374.292 1.00 53.22  ? 60  LYS C CG  1 
ATOM 2419 C CD  . LYS C 1 61  ? 244.721 273.660 374.887 1.00 53.22  ? 60  LYS C CD  1 
ATOM 2420 C CE  . LYS C 1 61  ? 243.760 274.336 373.932 1.00 53.22  ? 60  LYS C CE  1 
ATOM 2421 N NZ  . LYS C 1 61  ? 242.420 274.487 374.551 1.00 53.22  ? 60  LYS C NZ  1 
ATOM 2422 N N   . ASN C 1 62  ? 249.471 272.888 377.437 1.00 48.27  ? 61  ASN C N   1 
ATOM 2423 C CA  . ASN C 1 62  ? 250.342 272.025 378.222 1.00 48.27  ? 61  ASN C CA  1 
ATOM 2424 C C   . ASN C 1 62  ? 251.432 272.843 378.891 1.00 48.27  ? 61  ASN C C   1 
ATOM 2425 O O   . ASN C 1 62  ? 252.192 273.542 378.216 1.00 48.27  ? 61  ASN C O   1 
ATOM 2426 C CB  . ASN C 1 62  ? 250.964 270.944 377.347 1.00 48.27  ? 61  ASN C CB  1 
ATOM 2427 C CG  . ASN C 1 62  ? 249.938 269.990 376.795 1.00 48.27  ? 61  ASN C CG  1 
ATOM 2428 O OD1 . ASN C 1 62  ? 249.673 269.975 375.596 1.00 48.27  ? 61  ASN C OD1 1 
ATOM 2429 N ND2 . ASN C 1 62  ? 249.361 269.175 377.665 1.00 48.27  ? 61  ASN C ND2 1 
ATOM 2430 N N   . TYR C 1 63  ? 251.516 272.735 380.209 1.00 43.09  ? 62  TYR C N   1 
ATOM 2431 C CA  . TYR C 1 63  ? 252.562 273.363 380.998 1.00 43.09  ? 62  TYR C CA  1 
ATOM 2432 C C   . TYR C 1 63  ? 253.685 272.366 381.220 1.00 43.09  ? 62  TYR C C   1 
ATOM 2433 O O   . TYR C 1 63  ? 253.435 271.180 381.434 1.00 43.09  ? 62  TYR C O   1 
ATOM 2434 C CB  . TYR C 1 63  ? 252.003 273.850 382.329 1.00 43.09  ? 62  TYR C CB  1 
ATOM 2435 C CG  . TYR C 1 63  ? 251.067 275.011 382.161 1.00 43.09  ? 62  TYR C CG  1 
ATOM 2436 C CD1 . TYR C 1 63  ? 251.547 276.308 382.139 1.00 43.09  ? 62  TYR C CD1 1 
ATOM 2437 C CD2 . TYR C 1 63  ? 249.711 274.810 381.970 1.00 43.09  ? 62  TYR C CD2 1 
ATOM 2438 C CE1 . TYR C 1 63  ? 250.702 277.374 381.969 1.00 43.09  ? 62  TYR C CE1 1 
ATOM 2439 C CE2 . TYR C 1 63  ? 248.858 275.870 381.791 1.00 43.09  ? 62  TYR C CE2 1 
ATOM 2440 C CZ  . TYR C 1 63  ? 249.358 277.149 381.794 1.00 43.09  ? 62  TYR C CZ  1 
ATOM 2441 O OH  . TYR C 1 63  ? 248.503 278.210 381.621 1.00 43.09  ? 62  TYR C OH  1 
ATOM 2442 N N   . LYS C 1 64  ? 254.922 272.847 381.161 1.00 33.96  ? 63  LYS C N   1 
ATOM 2443 C CA  . LYS C 1 64  ? 256.073 271.961 381.069 1.00 33.96  ? 63  LYS C CA  1 
ATOM 2444 C C   . LYS C 1 64  ? 257.231 272.553 381.852 1.00 33.96  ? 63  LYS C C   1 
ATOM 2445 O O   . LYS C 1 64  ? 257.729 273.624 381.502 1.00 33.96  ? 63  LYS C O   1 
ATOM 2446 C CB  . LYS C 1 64  ? 256.460 271.751 379.607 1.00 33.96  ? 63  LYS C CB  1 
ATOM 2447 C CG  . LYS C 1 64  ? 257.560 270.745 379.393 1.00 33.96  ? 63  LYS C CG  1 
ATOM 2448 C CD  . LYS C 1 64  ? 257.748 270.439 377.923 1.00 33.96  ? 63  LYS C CD  1 
ATOM 2449 C CE  . LYS C 1 64  ? 258.432 271.581 377.198 1.00 33.96  ? 63  LYS C CE  1 
ATOM 2450 N NZ  . LYS C 1 64  ? 259.856 271.725 377.598 1.00 33.96  ? 63  LYS C NZ  1 
ATOM 2451 N N   . VAL C 1 65  ? 257.655 271.858 382.897 1.00 27.87  ? 64  VAL C N   1 
ATOM 2452 C CA  . VAL C 1 65  ? 258.780 272.259 383.731 1.00 27.87  ? 64  VAL C CA  1 
ATOM 2453 C C   . VAL C 1 65  ? 259.985 271.426 383.329 1.00 27.87  ? 64  VAL C C   1 
ATOM 2454 O O   . VAL C 1 65  ? 259.853 270.228 383.072 1.00 27.87  ? 64  VAL C O   1 
ATOM 2455 C CB  . VAL C 1 65  ? 258.429 272.076 385.219 1.00 27.87  ? 64  VAL C CB  1 
ATOM 2456 C CG1 . VAL C 1 65  ? 259.587 272.436 386.120 1.00 27.87  ? 64  VAL C CG1 1 
ATOM 2457 C CG2 . VAL C 1 65  ? 257.227 272.923 385.558 1.00 27.87  ? 64  VAL C CG2 1 
ATOM 2458 N N   . GLN C 1 66  ? 261.158 272.048 383.239 1.00 27.00  ? 65  GLN C N   1 
ATOM 2459 C CA  . GLN C 1 66  ? 262.357 271.314 382.866 1.00 27.00  ? 65  GLN C CA  1 
ATOM 2460 C C   . GLN C 1 66  ? 263.537 271.738 383.726 1.00 27.00  ? 65  GLN C C   1 
ATOM 2461 O O   . GLN C 1 66  ? 263.843 272.927 383.824 1.00 27.00  ? 65  GLN C O   1 
ATOM 2462 C CB  . GLN C 1 66  ? 262.664 271.512 381.384 1.00 27.00  ? 65  GLN C CB  1 
ATOM 2463 C CG  . GLN C 1 66  ? 263.764 270.623 380.871 1.00 27.00  ? 65  GLN C CG  1 
ATOM 2464 C CD  . GLN C 1 66  ? 263.841 270.648 379.374 1.00 27.00  ? 65  GLN C CD  1 
ATOM 2465 O OE1 . GLN C 1 66  ? 263.085 271.361 378.720 1.00 27.00  ? 65  GLN C OE1 1 
ATOM 2466 N NE2 . GLN C 1 66  ? 264.741 269.857 378.813 1.00 27.00  ? 65  GLN C NE2 1 
ATOM 2467 N N   . VAL C 1 67  ? 264.197 270.761 384.345 1.00 25.40  ? 66  VAL C N   1 
ATOM 2468 C CA  . VAL C 1 67  ? 265.334 270.988 385.230 1.00 25.40  ? 66  VAL C CA  1 
ATOM 2469 C C   . VAL C 1 67  ? 266.527 270.234 384.663 1.00 25.40  ? 66  VAL C C   1 
ATOM 2470 O O   . VAL C 1 67  ? 266.397 269.068 384.278 1.00 25.40  ? 66  VAL C O   1 
ATOM 2471 C CB  . VAL C 1 67  ? 265.025 270.530 386.667 1.00 25.40  ? 66  VAL C CB  1 
ATOM 2472 C CG1 . VAL C 1 67  ? 266.218 270.707 387.575 1.00 25.40  ? 66  VAL C CG1 1 
ATOM 2473 C CG2 . VAL C 1 67  ? 263.839 271.279 387.215 1.00 25.40  ? 66  VAL C CG2 1 
ATOM 2474 N N   . LYS C 1 68  ? 267.682 270.892 384.597 1.00 27.27  ? 67  LYS C N   1 
ATOM 2475 C CA  . LYS C 1 68  ? 268.906 270.248 384.149 1.00 27.27  ? 67  LYS C CA  1 
ATOM 2476 C C   . LYS C 1 68  ? 270.024 270.466 385.156 1.00 27.27  ? 67  LYS C C   1 
ATOM 2477 O O   . LYS C 1 68  ? 270.152 271.546 385.729 1.00 27.27  ? 67  LYS C O   1 
ATOM 2478 C CB  . LYS C 1 68  ? 269.345 270.758 382.790 1.00 27.27  ? 67  LYS C CB  1 
ATOM 2479 C CG  . LYS C 1 68  ? 268.393 270.423 381.677 1.00 27.27  ? 67  LYS C CG  1 
ATOM 2480 C CD  . LYS C 1 68  ? 268.996 270.779 380.347 1.00 27.27  ? 67  LYS C CD  1 
ATOM 2481 C CE  . LYS C 1 68  ? 268.040 270.473 379.225 1.00 27.27  ? 67  LYS C CE  1 
ATOM 2482 N NZ  . LYS C 1 68  ? 268.639 270.765 377.901 1.00 27.27  ? 67  LYS C NZ  1 
ATOM 2483 N N   . ILE C 1 69  ? 270.829 269.427 385.364 1.00 27.96  ? 68  ILE C N   1 
ATOM 2484 C CA  . ILE C 1 69  ? 272.003 269.463 386.228 1.00 27.96  ? 68  ILE C CA  1 
ATOM 2485 C C   . ILE C 1 69  ? 273.173 268.918 385.425 1.00 27.96  ? 68  ILE C C   1 
ATOM 2486 O O   . ILE C 1 69  ? 273.031 267.900 384.744 1.00 27.96  ? 68  ILE C O   1 
ATOM 2487 C CB  . ILE C 1 69  ? 271.791 268.627 387.508 1.00 27.96  ? 68  ILE C CB  1 
ATOM 2488 C CG1 . ILE C 1 69  ? 270.638 269.172 388.338 1.00 27.96  ? 68  ILE C CG1 1 
ATOM 2489 C CG2 . ILE C 1 69  ? 273.036 268.578 388.359 1.00 27.96  ? 68  ILE C CG2 1 
ATOM 2490 C CD1 . ILE C 1 69  ? 270.242 268.245 389.447 1.00 27.96  ? 68  ILE C CD1 1 
ATOM 2491 N N   . GLN C 1 70  ? 274.321 269.588 385.483 1.00 32.30  ? 69  GLN C N   1 
ATOM 2492 C CA  . GLN C 1 70  ? 275.539 269.019 384.921 1.00 32.30  ? 69  GLN C CA  1 
ATOM 2493 C C   . GLN C 1 70  ? 276.724 269.339 385.817 1.00 32.30  ? 69  GLN C C   1 
ATOM 2494 O O   . GLN C 1 70  ? 276.857 270.466 386.301 1.00 32.30  ? 69  GLN C O   1 
ATOM 2495 C CB  . GLN C 1 70  ? 275.770 269.500 383.484 1.00 32.30  ? 69  GLN C CB  1 
ATOM 2496 C CG  . GLN C 1 70  ? 275.916 270.986 383.297 1.00 32.30  ? 69  GLN C CG  1 
ATOM 2497 C CD  . GLN C 1 70  ? 276.036 271.374 381.843 1.00 32.30  ? 69  GLN C CD  1 
ATOM 2498 O OE1 . GLN C 1 70  ? 276.023 270.525 380.961 1.00 32.30  ? 69  GLN C OE1 1 
ATOM 2499 N NE2 . GLN C 1 70  ? 276.162 272.665 381.586 1.00 32.30  ? 69  GLN C NE2 1 
ATOM 2500 N N   . ASN C 1 71  ? 277.557 268.336 386.080 1.00 34.70  ? 70  ASN C N   1 
ATOM 2501 C CA  . ASN C 1 71  ? 278.680 268.493 386.995 1.00 34.70  ? 70  ASN C CA  1 
ATOM 2502 C C   . ASN C 1 71  ? 279.950 268.029 386.297 1.00 34.70  ? 70  ASN C C   1 
ATOM 2503 O O   . ASN C 1 71  ? 280.059 266.838 385.947 1.00 34.70  ? 70  ASN C O   1 
ATOM 2504 C CB  . ASN C 1 71  ? 278.476 267.699 388.283 1.00 34.70  ? 70  ASN C CB  1 
ATOM 2505 C CG  . ASN C 1 71  ? 277.135 267.944 388.914 1.00 34.70  ? 70  ASN C CG  1 
ATOM 2506 O OD1 . ASN C 1 71  ? 276.404 267.009 389.218 1.00 34.70  ? 70  ASN C OD1 1 
ATOM 2507 N ND2 . ASN C 1 71  ? 276.769 269.200 389.047 1.00 34.70  ? 70  ASN C ND2 1 
ATOM 2508 N N   . PRO C 1 72  ? 280.925 268.903 386.071 1.00 39.95  ? 71  PRO C N   1 
ATOM 2509 C CA  . PRO C 1 72  ? 282.187 268.469 385.477 1.00 39.95  ? 71  PRO C CA  1 
ATOM 2510 C C   . PRO C 1 72  ? 283.194 268.027 386.522 1.00 39.95  ? 71  PRO C C   1 
ATOM 2511 O O   . PRO C 1 72  ? 283.097 268.352 387.705 1.00 39.95  ? 71  PRO C O   1 
ATOM 2512 C CB  . PRO C 1 72  ? 282.676 269.735 384.769 1.00 39.95  ? 71  PRO C CB  1 
ATOM 2513 C CG  . PRO C 1 72  ? 282.141 270.810 385.587 1.00 39.95  ? 71  PRO C CG  1 
ATOM 2514 C CD  . PRO C 1 72  ? 280.819 270.368 386.105 1.00 39.95  ? 71  PRO C CD  1 
ATOM 2515 N N   . THR C 1 73  ? 284.182 267.271 386.055 1.00 47.00  ? 72  THR C N   1 
ATOM 2516 C CA  . THR C 1 73  ? 285.310 266.847 386.871 1.00 47.00  ? 72  THR C CA  1 
ATOM 2517 C C   . THR C 1 73  ? 286.591 267.369 386.244 1.00 47.00  ? 72  THR C C   1 
ATOM 2518 O O   . THR C 1 73  ? 286.786 267.245 385.032 1.00 47.00  ? 72  THR C O   1 
ATOM 2519 C CB  . THR C 1 73  ? 285.369 265.331 386.996 1.00 47.00  ? 72  THR C CB  1 
ATOM 2520 O OG1 . THR C 1 73  ? 285.464 264.760 385.690 1.00 47.00  ? 72  THR C OG1 1 
ATOM 2521 C CG2 . THR C 1 73  ? 284.135 264.807 387.692 1.00 47.00  ? 72  THR C CG2 1 
ATOM 2522 N N   . ALA C 1 74  ? 287.457 267.945 387.066 1.00 56.78  ? 73  ALA C N   1 
ATOM 2523 C CA  . ALA C 1 74  ? 288.669 268.596 386.600 1.00 56.78  ? 73  ALA C CA  1 
ATOM 2524 C C   . ALA C 1 74  ? 289.816 267.602 386.504 1.00 56.78  ? 73  ALA C C   1 
ATOM 2525 O O   . ALA C 1 74  ? 289.847 266.585 387.200 1.00 56.78  ? 73  ALA C O   1 
ATOM 2526 C CB  . ALA C 1 74  ? 289.060 269.743 387.531 1.00 56.78  ? 73  ALA C CB  1 
ATOM 2527 N N   . CYS C 1 75  ? 290.763 267.910 385.623 1.00 65.85  ? 74  CYS C N   1 
ATOM 2528 C CA  . CYS C 1 75  ? 291.939 267.072 385.409 1.00 65.85  ? 74  CYS C CA  1 
ATOM 2529 C C   . CYS C 1 75  ? 293.118 267.976 385.095 1.00 65.85  ? 74  CYS C C   1 
ATOM 2530 O O   . CYS C 1 75  ? 293.207 268.514 383.988 1.00 65.85  ? 74  CYS C O   1 
ATOM 2531 C CB  . CYS C 1 75  ? 291.716 266.082 384.274 1.00 65.85  ? 74  CYS C CB  1 
ATOM 2532 S SG  . CYS C 1 75  ? 293.125 265.000 383.962 1.00 65.85  ? 74  CYS C SG  1 
ATOM 2533 N N   . THR C 1 76  ? 294.026 268.131 386.052 1.00 74.03  ? 75  THR C N   1 
ATOM 2534 C CA  . THR C 1 76  ? 295.243 268.893 385.807 1.00 74.03  ? 75  THR C CA  1 
ATOM 2535 C C   . THR C 1 76  ? 296.202 268.073 384.956 1.00 74.03  ? 75  THR C C   1 
ATOM 2536 O O   . THR C 1 76  ? 297.057 267.357 385.489 1.00 74.03  ? 75  THR C O   1 
ATOM 2537 C CB  . THR C 1 76  ? 295.903 269.290 387.127 1.00 74.03  ? 75  THR C CB  1 
ATOM 2538 O OG1 . THR C 1 76  ? 296.264 268.111 387.856 1.00 74.03  ? 75  THR C OG1 1 
ATOM 2539 C CG2 . THR C 1 76  ? 294.950 270.121 387.966 1.00 74.03  ? 75  THR C CG2 1 
ATOM 2540 N N   . ALA C 1 77  ? 296.055 268.158 383.637 1.00 80.84  ? 76  ALA C N   1 
ATOM 2541 C CA  . ALA C 1 77  ? 296.909 267.404 382.733 1.00 80.84  ? 76  ALA C CA  1 
ATOM 2542 C C   . ALA C 1 77  ? 298.319 267.978 382.723 1.00 80.84  ? 76  ALA C C   1 
ATOM 2543 O O   . ALA C 1 77  ? 298.527 269.181 382.903 1.00 80.84  ? 76  ALA C O   1 
ATOM 2544 C CB  . ALA C 1 77  ? 296.336 267.415 381.318 1.00 80.84  ? 76  ALA C CB  1 
ATOM 2545 N N   . ASN C 1 78  ? 299.293 267.101 382.514 1.00 88.62  ? 77  ASN C N   1 
ATOM 2546 C CA  . ASN C 1 78  ? 300.686 267.515 382.499 1.00 88.62  ? 77  ASN C CA  1 
ATOM 2547 C C   . ASN C 1 78  ? 301.009 268.243 381.201 1.00 88.62  ? 77  ASN C C   1 
ATOM 2548 O O   . ASN C 1 78  ? 300.605 267.820 380.115 1.00 88.62  ? 77  ASN C O   1 
ATOM 2549 C CB  . ASN C 1 78  ? 301.604 266.308 382.674 1.00 88.62  ? 77  ASN C CB  1 
ATOM 2550 C CG  . ASN C 1 78  ? 301.411 265.626 384.012 1.00 88.62  ? 77  ASN C CG  1 
ATOM 2551 O OD1 . ASN C 1 78  ? 300.988 264.473 384.077 1.00 88.62  ? 77  ASN C OD1 1 
ATOM 2552 N ND2 . ASN C 1 78  ? 301.710 266.343 385.089 1.00 88.62  ? 77  ASN C ND2 1 
ATOM 2553 N N   . GLY C 1 79  ? 301.738 269.347 381.324 1.00 87.49  ? 78  GLY C N   1 
ATOM 2554 C CA  . GLY C 1 79  ? 302.050 270.183 380.188 1.00 87.49  ? 78  GLY C CA  1 
ATOM 2555 C C   . GLY C 1 79  ? 301.070 271.302 379.927 1.00 87.49  ? 78  GLY C C   1 
ATOM 2556 O O   . GLY C 1 79  ? 301.188 271.978 378.899 1.00 87.49  ? 78  GLY C O   1 
ATOM 2557 N N   . SER C 1 80  ? 300.107 271.521 380.817 1.00 82.37  ? 79  SER C N   1 
ATOM 2558 C CA  . SER C 1 80  ? 299.126 272.577 380.641 1.00 82.37  ? 79  SER C CA  1 
ATOM 2559 C C   . SER C 1 80  ? 298.902 273.276 381.970 1.00 82.37  ? 79  SER C C   1 
ATOM 2560 O O   . SER C 1 80  ? 298.871 272.631 383.021 1.00 82.37  ? 79  SER C O   1 
ATOM 2561 C CB  . SER C 1 80  ? 297.802 272.026 380.104 1.00 82.37  ? 79  SER C CB  1 
ATOM 2562 O OG  . SER C 1 80  ? 296.854 273.065 379.932 1.00 82.37  ? 79  SER C OG  1 
ATOM 2563 N N   . CYS C 1 81  ? 298.754 274.598 381.915 1.00 78.58  ? 80  CYS C N   1 
ATOM 2564 C CA  . CYS C 1 81  ? 298.520 275.384 383.118 1.00 78.58  ? 80  CYS C CA  1 
ATOM 2565 C C   . CYS C 1 81  ? 297.054 275.421 383.514 1.00 78.58  ? 80  CYS C C   1 
ATOM 2566 O O   . CYS C 1 81  ? 296.735 275.889 384.612 1.00 78.58  ? 80  CYS C O   1 
ATOM 2567 C CB  . CYS C 1 81  ? 299.029 276.811 382.918 1.00 78.58  ? 80  CYS C CB  1 
ATOM 2568 S SG  . CYS C 1 81  ? 300.810 276.949 382.646 1.00 78.58  ? 80  CYS C SG  1 
ATOM 2569 N N   . ASP C 1 82  ? 296.166 274.934 382.656 1.00 69.80  ? 81  ASP C N   1 
ATOM 2570 C CA  . ASP C 1 82  ? 294.736 274.993 382.861 1.00 69.80  ? 81  ASP C CA  1 
ATOM 2571 C C   . ASP C 1 82  ? 294.191 273.601 383.115 1.00 69.80  ? 81  ASP C C   1 
ATOM 2572 O O   . ASP C 1 82  ? 294.572 272.661 382.406 1.00 69.80  ? 81  ASP C O   1 
ATOM 2573 C CB  . ASP C 1 82  ? 294.052 275.595 381.633 1.00 69.80  ? 81  ASP C CB  1 
ATOM 2574 C CG  . ASP C 1 82  ? 294.373 277.056 381.446 1.00 69.80  ? 81  ASP C CG  1 
ATOM 2575 O OD1 . ASP C 1 82  ? 294.617 277.746 382.455 1.00 69.80  ? 81  ASP C OD1 1 
ATOM 2576 O OD2 . ASP C 1 82  ? 294.376 277.515 380.286 1.00 69.80  ? 81  ASP C OD2 1 
ATOM 2577 N N   . PRO C 1 83  ? 293.321 273.419 384.103 1.00 63.21  ? 82  PRO C N   1 
ATOM 2578 C CA  . PRO C 1 83  ? 292.597 272.154 384.208 1.00 63.21  ? 82  PRO C CA  1 
ATOM 2579 C C   . PRO C 1 83  ? 291.603 272.020 383.072 1.00 63.21  ? 82  PRO C C   1 
ATOM 2580 O O   . PRO C 1 83  ? 291.092 273.008 382.545 1.00 63.21  ? 82  PRO C O   1 
ATOM 2581 C CB  . PRO C 1 83  ? 291.886 272.262 385.559 1.00 63.21  ? 82  PRO C CB  1 
ATOM 2582 C CG  . PRO C 1 83  ? 291.737 273.714 385.776 1.00 63.21  ? 82  PRO C CG  1 
ATOM 2583 C CD  . PRO C 1 83  ? 292.952 274.353 385.178 1.00 63.21  ? 82  PRO C CD  1 
ATOM 2584 N N   . SER C 1 84  ? 291.344 270.781 382.686 1.00 58.07  ? 83  SER C N   1 
ATOM 2585 C CA  . SER C 1 84  ? 290.392 270.489 381.632 1.00 58.07  ? 83  SER C CA  1 
ATOM 2586 C C   . SER C 1 84  ? 289.260 269.646 382.197 1.00 58.07  ? 83  SER C C   1 
ATOM 2587 O O   . SER C 1 84  ? 289.288 269.215 383.351 1.00 58.07  ? 83  SER C O   1 
ATOM 2588 C CB  . SER C 1 84  ? 291.070 269.774 380.460 1.00 58.07  ? 83  SER C CB  1 
ATOM 2589 O OG  . SER C 1 84  ? 291.569 268.509 380.855 1.00 58.07  ? 83  SER C OG  1 
ATOM 2590 N N   . VAL C 1 85  ? 288.249 269.421 381.373 1.00 50.00  ? 84  VAL C N   1 
ATOM 2591 C CA  . VAL C 1 85  ? 287.075 268.659 381.768 1.00 50.00  ? 84  VAL C CA  1 
ATOM 2592 C C   . VAL C 1 85  ? 287.201 267.265 381.171 1.00 50.00  ? 84  VAL C C   1 
ATOM 2593 O O   . VAL C 1 85  ? 287.143 267.095 379.949 1.00 50.00  ? 84  VAL C O   1 
ATOM 2594 C CB  . VAL C 1 85  ? 285.780 269.350 381.328 1.00 50.00  ? 84  VAL C CB  1 
ATOM 2595 C CG1 . VAL C 1 85  ? 284.602 268.458 381.601 1.00 50.00  ? 84  VAL C CG1 1 
ATOM 2596 C CG2 . VAL C 1 85  ? 285.617 270.660 382.065 1.00 50.00  ? 84  VAL C CG2 1 
ATOM 2597 N N   . THR C 1 86  ? 287.393 266.268 382.035 1.00 48.89  ? 85  THR C N   1 
ATOM 2598 C CA  . THR C 1 86  ? 287.425 264.884 381.581 1.00 48.89  ? 85  THR C CA  1 
ATOM 2599 C C   . THR C 1 86  ? 286.050 264.436 381.110 1.00 48.89  ? 85  THR C C   1 
ATOM 2600 O O   . THR C 1 86  ? 285.904 263.888 380.012 1.00 48.89  ? 85  THR C O   1 
ATOM 2601 C CB  . THR C 1 86  ? 287.916 263.974 382.704 1.00 48.89  ? 85  THR C CB  1 
ATOM 2602 O OG1 . THR C 1 86  ? 289.242 264.346 383.075 1.00 48.89  ? 85  THR C OG1 1 
ATOM 2603 C CG2 . THR C 1 86  ? 287.921 262.521 382.257 1.00 48.89  ? 85  THR C CG2 1 
ATOM 2604 N N   . ARG C 1 87  ? 285.028 264.687 381.918 1.00 42.61  ? 86  ARG C N   1 
ATOM 2605 C CA  . ARG C 1 87  ? 283.711 264.124 381.685 1.00 42.61  ? 86  ARG C CA  1 
ATOM 2606 C C   . ARG C 1 87  ? 282.682 264.969 382.417 1.00 42.61  ? 86  ARG C C   1 
ATOM 2607 O O   . ARG C 1 87  ? 283.016 265.795 383.267 1.00 42.61  ? 86  ARG C O   1 
ATOM 2608 C CB  . ARG C 1 87  ? 283.656 262.684 382.167 1.00 42.61  ? 86  ARG C CB  1 
ATOM 2609 C CG  . ARG C 1 87  ? 283.851 262.610 383.645 1.00 42.61  ? 86  ARG C CG  1 
ATOM 2610 C CD  . ARG C 1 87  ? 283.932 261.205 384.130 1.00 42.61  ? 86  ARG C CD  1 
ATOM 2611 N NE  . ARG C 1 87  ? 284.086 261.185 385.573 1.00 42.61  ? 86  ARG C NE  1 
ATOM 2612 C CZ  . ARG C 1 87  ? 285.256 261.238 386.190 1.00 42.61  ? 86  ARG C CZ  1 
ATOM 2613 N NH1 . ARG C 1 87  ? 286.374 261.303 385.488 1.00 42.61  ? 86  ARG C NH1 1 
ATOM 2614 N NH2 . ARG C 1 87  ? 285.307 261.216 387.509 1.00 42.61  ? 86  ARG C NH2 1 
ATOM 2615 N N   . GLN C 1 88  ? 281.422 264.738 382.080 1.00 37.95  ? 87  GLN C N   1 
ATOM 2616 C CA  . GLN C 1 88  ? 280.281 265.402 382.684 1.00 37.95  ? 87  GLN C CA  1 
ATOM 2617 C C   . GLN C 1 88  ? 279.447 264.379 383.442 1.00 37.95  ? 87  GLN C C   1 
ATOM 2618 O O   . GLN C 1 88  ? 279.710 263.177 383.405 1.00 37.95  ? 87  GLN C O   1 
ATOM 2619 C CB  . GLN C 1 88  ? 279.421 266.077 381.614 1.00 37.95  ? 87  GLN C CB  1 
ATOM 2620 C CG  . GLN C 1 88  ? 280.073 267.187 380.819 1.00 37.95  ? 87  GLN C CG  1 
ATOM 2621 C CD  . GLN C 1 88  ? 280.226 268.471 381.588 1.00 37.95  ? 87  GLN C CD  1 
ATOM 2622 O OE1 . GLN C 1 88  ? 281.328 268.865 381.936 1.00 37.95  ? 87  GLN C OE1 1 
ATOM 2623 N NE2 . GLN C 1 88  ? 279.118 269.147 381.832 1.00 37.95  ? 87  GLN C NE2 1 
ATOM 2624 N N   . ALA C 1 89  ? 278.419 264.872 384.124 1.00 32.98  ? 88  ALA C N   1 
ATOM 2625 C CA  . ALA C 1 89  ? 277.456 264.027 384.823 1.00 32.98  ? 88  ALA C CA  1 
ATOM 2626 C C   . ALA C 1 89  ? 276.112 264.727 384.749 1.00 32.98  ? 88  ALA C C   1 
ATOM 2627 O O   . ALA C 1 89  ? 275.868 265.670 385.502 1.00 32.98  ? 88  ALA C O   1 
ATOM 2628 C CB  . ALA C 1 89  ? 277.866 263.792 386.272 1.00 32.98  ? 88  ALA C CB  1 
ATOM 2629 N N   . TYR C 1 90  ? 275.241 264.266 383.867 1.00 30.02  ? 89  TYR C N   1 
ATOM 2630 C CA  . TYR C 1 90  ? 274.036 265.010 383.544 1.00 30.02  ? 89  TYR C CA  1 
ATOM 2631 C C   . TYR C 1 90  ? 272.841 264.521 384.345 1.00 30.02  ? 89  TYR C C   1 
ATOM 2632 O O   . TYR C 1 90  ? 272.873 263.471 384.985 1.00 30.02  ? 89  TYR C O   1 
ATOM 2633 C CB  . TYR C 1 90  ? 273.716 264.901 382.060 1.00 30.02  ? 89  TYR C CB  1 
ATOM 2634 C CG  . TYR C 1 90  ? 274.755 265.506 381.173 1.00 30.02  ? 89  TYR C CG  1 
ATOM 2635 C CD1 . TYR C 1 90  ? 274.850 266.874 381.028 1.00 30.02  ? 89  TYR C CD1 1 
ATOM 2636 C CD2 . TYR C 1 90  ? 275.626 264.708 380.453 1.00 30.02  ? 89  TYR C CD2 1 
ATOM 2637 C CE1 . TYR C 1 90  ? 275.797 267.431 380.205 1.00 30.02  ? 89  TYR C CE1 1 
ATOM 2638 C CE2 . TYR C 1 90  ? 276.568 265.255 379.626 1.00 30.02  ? 89  TYR C CE2 1 
ATOM 2639 C CZ  . TYR C 1 90  ? 276.650 266.619 379.507 1.00 30.02  ? 89  TYR C CZ  1 
ATOM 2640 O OH  . TYR C 1 90  ? 277.592 267.174 378.680 1.00 30.02  ? 89  TYR C OH  1 
ATOM 2641 N N   . ALA C 1 91  ? 271.778 265.317 384.299 1.00 26.95  ? 90  ALA C N   1 
ATOM 2642 C CA  . ALA C 1 91  ? 270.491 264.992 384.888 1.00 26.95  ? 90  ALA C CA  1 
ATOM 2643 C C   . ALA C 1 91  ? 269.456 265.842 384.180 1.00 26.95  ? 90  ALA C C   1 
ATOM 2644 O O   . ALA C 1 91  ? 269.676 267.034 383.977 1.00 26.95  ? 90  ALA C O   1 
ATOM 2645 C CB  . ALA C 1 91  ? 270.462 265.256 386.392 1.00 26.95  ? 90  ALA C CB  1 
ATOM 2646 N N   . ASP C 1 92  ? 268.340 265.239 383.791 1.00 28.31  ? 91  ASP C N   1 
ATOM 2647 C CA  . ASP C 1 92  ? 267.360 265.927 382.953 1.00 28.31  ? 91  ASP C CA  1 
ATOM 2648 C C   . ASP C 1 92  ? 265.969 265.546 383.440 1.00 28.31  ? 91  ASP C C   1 
ATOM 2649 O O   . ASP C 1 92  ? 265.458 264.479 383.098 1.00 28.31  ? 91  ASP C O   1 
ATOM 2650 C CB  . ASP C 1 92  ? 267.553 265.563 381.487 1.00 28.31  ? 91  ASP C CB  1 
ATOM 2651 C CG  . ASP C 1 92  ? 266.803 266.489 380.549 1.00 28.31  ? 91  ASP C CG  1 
ATOM 2652 O OD1 . ASP C 1 92  ? 266.135 267.426 381.022 1.00 28.31  ? 91  ASP C OD1 1 
ATOM 2653 O OD2 . ASP C 1 92  ? 266.884 266.278 379.322 1.00 28.31  ? 91  ASP C OD2 1 
ATOM 2654 N N   . VAL C 1 93  ? 265.349 266.433 384.210 1.00 25.37  ? 92  VAL C N   1 
ATOM 2655 C CA  . VAL C 1 93  ? 264.017 266.215 384.758 1.00 25.37  ? 92  VAL C CA  1 
ATOM 2656 C C   . VAL C 1 93  ? 263.038 267.066 383.971 1.00 25.37  ? 92  VAL C C   1 
ATOM 2657 O O   . VAL C 1 93  ? 263.209 268.285 383.885 1.00 25.37  ? 92  VAL C O   1 
ATOM 2658 C CB  . VAL C 1 93  ? 263.965 266.569 386.250 1.00 25.37  ? 92  VAL C CB  1 
ATOM 2659 C CG1 . VAL C 1 93  ? 262.573 266.406 386.763 1.00 25.37  ? 92  VAL C CG1 1 
ATOM 2660 C CG2 . VAL C 1 93  ? 264.917 265.698 387.029 1.00 25.37  ? 92  VAL C CG2 1 
ATOM 2661 N N   . THR C 1 94  ? 262.014 266.438 383.402 1.00 25.04  ? 93  THR C N   1 
ATOM 2662 C CA  . THR C 1 94  ? 261.017 267.166 382.623 1.00 25.04  ? 93  THR C CA  1 
ATOM 2663 C C   . THR C 1 94  ? 259.607 266.756 383.034 1.00 25.04  ? 93  THR C C   1 
ATOM 2664 O O   . THR C 1 94  ? 259.212 265.597 382.890 1.00 25.04  ? 93  THR C O   1 
ATOM 2665 C CB  . THR C 1 94  ? 261.249 266.997 381.116 1.00 25.04  ? 93  THR C CB  1 
ATOM 2666 O OG1 . THR C 1 94  ? 260.141 267.537 380.386 1.00 25.04  ? 93  THR C OG1 1 
ATOM 2667 C CG2 . THR C 1 94  ? 261.546 265.561 380.706 1.00 25.04  ? 93  THR C CG2 1 
ATOM 2668 N N   . PHE C 1 95  ? 258.854 267.712 383.568 1.00 26.86  ? 94  PHE C N   1 
ATOM 2669 C CA  . PHE C 1 95  ? 257.461 267.504 383.921 1.00 26.86  ? 94  PHE C CA  1 
ATOM 2670 C C   . PHE C 1 95  ? 256.560 267.931 382.770 1.00 26.86  ? 94  PHE C C   1 
ATOM 2671 O O   . PHE C 1 95  ? 257.003 268.521 381.787 1.00 26.86  ? 94  PHE C O   1 
ATOM 2672 C CB  . PHE C 1 95  ? 257.111 268.274 385.182 1.00 26.86  ? 94  PHE C CB  1 
ATOM 2673 C CG  . PHE C 1 95  ? 257.776 267.758 386.403 1.00 26.86  ? 94  PHE C CG  1 
ATOM 2674 C CD1 . PHE C 1 95  ? 257.252 266.680 387.081 1.00 26.86  ? 94  PHE C CD1 1 
ATOM 2675 C CD2 . PHE C 1 95  ? 258.931 268.336 386.872 1.00 26.86  ? 94  PHE C CD2 1 
ATOM 2676 C CE1 . PHE C 1 95  ? 257.860 266.201 388.209 1.00 26.86  ? 94  PHE C CE1 1 
ATOM 2677 C CE2 . PHE C 1 95  ? 259.542 267.862 388.005 1.00 26.86  ? 94  PHE C CE2 1 
ATOM 2678 C CZ  . PHE C 1 95  ? 259.005 266.786 388.669 1.00 26.86  ? 94  PHE C CZ  1 
ATOM 2679 N N   . SER C 1 96  ? 255.274 267.621 382.904 1.00 31.08  ? 95  SER C N   1 
ATOM 2680 C CA  . SER C 1 96  ? 254.305 267.853 381.839 1.00 31.08  ? 95  SER C CA  1 
ATOM 2681 C C   . SER C 1 96  ? 252.917 267.800 382.448 1.00 31.08  ? 95  SER C C   1 
ATOM 2682 O O   . SER C 1 96  ? 252.519 266.758 382.970 1.00 31.08  ? 95  SER C O   1 
ATOM 2683 C CB  . SER C 1 96  ? 254.443 266.804 380.743 1.00 31.08  ? 95  SER C CB  1 
ATOM 2684 O OG  . SER C 1 96  ? 253.455 266.982 379.750 1.00 31.08  ? 95  SER C OG  1 
ATOM 2685 N N   . PHE C 1 97  ? 252.175 268.897 382.369 1.00 35.49  ? 96  PHE C N   1 
ATOM 2686 C CA  . PHE C 1 97  ? 250.842 268.957 382.941 1.00 35.49  ? 96  PHE C CA  1 
ATOM 2687 C C   . PHE C 1 97  ? 249.883 269.546 381.921 1.00 35.49  ? 96  PHE C C   1 
ATOM 2688 O O   . PHE C 1 97  ? 250.296 270.082 380.894 1.00 35.49  ? 96  PHE C O   1 
ATOM 2689 C CB  . PHE C 1 97  ? 250.830 269.790 384.217 1.00 35.49  ? 96  PHE C CB  1 
ATOM 2690 C CG  . PHE C 1 97  ? 251.773 269.293 385.260 1.00 35.49  ? 96  PHE C CG  1 
ATOM 2691 C CD1 . PHE C 1 97  ? 251.483 268.150 385.973 1.00 35.49  ? 96  PHE C CD1 1 
ATOM 2692 C CD2 . PHE C 1 97  ? 252.942 269.976 385.540 1.00 35.49  ? 96  PHE C CD2 1 
ATOM 2693 C CE1 . PHE C 1 97  ? 252.343 267.688 386.928 1.00 35.49  ? 96  PHE C CE1 1 
ATOM 2694 C CE2 . PHE C 1 97  ? 253.804 269.516 386.509 1.00 35.49  ? 96  PHE C CE2 1 
ATOM 2695 C CZ  . PHE C 1 97  ? 253.504 268.372 387.196 1.00 35.49  ? 96  PHE C CZ  1 
ATOM 2696 N N   . THR C 1 98  ? 248.592 269.436 382.207 1.00 39.89  ? 97  THR C N   1 
ATOM 2697 C CA  . THR C 1 98  ? 247.571 270.076 381.393 1.00 39.89  ? 97  THR C CA  1 
ATOM 2698 C C   . THR C 1 98  ? 246.987 271.273 382.127 1.00 39.89  ? 97  THR C C   1 
ATOM 2699 O O   . THR C 1 98  ? 247.202 271.470 383.323 1.00 39.89  ? 97  THR C O   1 
ATOM 2700 C CB  . THR C 1 98  ? 246.459 269.097 381.026 1.00 39.89  ? 97  THR C CB  1 
ATOM 2701 O OG1 . THR C 1 98  ? 245.843 268.603 382.218 1.00 39.89  ? 97  THR C OG1 1 
ATOM 2702 C CG2 . THR C 1 98  ? 247.011 267.938 380.231 1.00 39.89  ? 97  THR C CG2 1 
ATOM 2703 N N   . GLN C 1 99  ? 246.217 272.072 381.392 1.00 43.68  ? 98  GLN C N   1 
ATOM 2704 C CA  . GLN C 1 99  ? 245.696 273.320 381.927 1.00 43.68  ? 98  GLN C CA  1 
ATOM 2705 C C   . GLN C 1 99  ? 244.533 273.133 382.886 1.00 43.68  ? 98  GLN C C   1 
ATOM 2706 O O   . GLN C 1 99  ? 244.098 274.114 383.492 1.00 43.68  ? 98  GLN C O   1 
ATOM 2707 C CB  . GLN C 1 99  ? 245.257 274.236 380.792 1.00 43.68  ? 98  GLN C CB  1 
ATOM 2708 C CG  . GLN C 1 99  ? 244.105 273.684 379.999 1.00 43.68  ? 98  GLN C CG  1 
ATOM 2709 C CD  . GLN C 1 99  ? 243.645 274.635 378.929 1.00 43.68  ? 98  GLN C CD  1 
ATOM 2710 O OE1 . GLN C 1 99  ? 244.146 275.750 378.822 1.00 43.68  ? 98  GLN C OE1 1 
ATOM 2711 N NE2 . GLN C 1 99  ? 242.678 274.207 378.133 1.00 43.68  ? 98  GLN C NE2 1 
ATOM 2712 N N   . TYR C 1 100 ? 244.013 271.918 383.041 1.00 40.42  ? 99  TYR C N   1 
ATOM 2713 C CA  . TYR C 1 100 ? 242.987 271.636 384.035 1.00 40.42  ? 99  TYR C CA  1 
ATOM 2714 C C   . TYR C 1 100 ? 243.530 270.872 385.232 1.00 40.42  ? 99  TYR C C   1 
ATOM 2715 O O   . TYR C 1 100 ? 242.749 270.445 386.084 1.00 40.42  ? 99  TYR C O   1 
ATOM 2716 C CB  . TYR C 1 100 ? 241.830 270.865 383.404 1.00 40.42  ? 99  TYR C CB  1 
ATOM 2717 C CG  . TYR C 1 100 ? 240.957 271.708 382.505 1.00 40.42  ? 99  TYR C CG  1 
ATOM 2718 C CD1 . TYR C 1 100 ? 239.956 272.504 383.035 1.00 40.42  ? 99  TYR C CD1 1 
ATOM 2719 C CD2 . TYR C 1 100 ? 241.134 271.706 381.132 1.00 40.42  ? 99  TYR C CD2 1 
ATOM 2720 C CE1 . TYR C 1 100 ? 239.155 273.273 382.224 1.00 40.42  ? 99  TYR C CE1 1 
ATOM 2721 C CE2 . TYR C 1 100 ? 240.340 272.468 380.312 1.00 40.42  ? 99  TYR C CE2 1 
ATOM 2722 C CZ  . TYR C 1 100 ? 239.354 273.252 380.865 1.00 40.42  ? 99  TYR C CZ  1 
ATOM 2723 O OH  . TYR C 1 100 ? 238.559 274.018 380.048 1.00 40.42  ? 99  TYR C OH  1 
ATOM 2724 N N   . SER C 1 101 ? 244.845 270.703 385.323 1.00 39.29  ? 100 SER C N   1 
ATOM 2725 C CA  . SER C 1 101 ? 245.446 270.043 386.470 1.00 39.29  ? 100 SER C CA  1 
ATOM 2726 C C   . SER C 1 101 ? 245.441 270.959 387.681 1.00 39.29  ? 100 SER C C   1 
ATOM 2727 O O   . SER C 1 101 ? 245.496 272.183 387.561 1.00 39.29  ? 100 SER C O   1 
ATOM 2728 C CB  . SER C 1 101 ? 246.872 269.624 386.149 1.00 39.29  ? 100 SER C CB  1 
ATOM 2729 O OG  . SER C 1 101 ? 247.669 270.760 385.900 1.00 39.29  ? 100 SER C OG  1 
ATOM 2730 N N   . THR C 1 102 ? 245.379 270.356 388.857 1.00 41.53  ? 101 THR C N   1 
ATOM 2731 C CA  . THR C 1 102 ? 245.277 271.106 390.092 1.00 41.53  ? 101 THR C CA  1 
ATOM 2732 C C   . THR C 1 102 ? 246.606 271.084 390.831 1.00 41.53  ? 101 THR C C   1 
ATOM 2733 O O   . THR C 1 102 ? 247.573 270.458 390.403 1.00 41.53  ? 101 THR C O   1 
ATOM 2734 C CB  . THR C 1 102 ? 244.147 270.557 390.957 1.00 41.53  ? 101 THR C CB  1 
ATOM 2735 O OG1 . THR C 1 102 ? 244.421 269.198 391.302 1.00 41.53  ? 101 THR C OG1 1 
ATOM 2736 C CG2 . THR C 1 102 ? 242.840 270.614 390.199 1.00 41.53  ? 101 THR C CG2 1 
ATOM 2737 N N   . ASP C 1 103 ? 246.647 271.794 391.958 1.00 43.18  ? 102 ASP C N   1 
ATOM 2738 C CA  . ASP C 1 103 ? 247.893 271.974 392.690 1.00 43.18  ? 102 ASP C CA  1 
ATOM 2739 C C   . ASP C 1 103 ? 248.337 270.687 393.362 1.00 43.18  ? 102 ASP C C   1 
ATOM 2740 O O   . ASP C 1 103 ? 249.537 270.402 393.416 1.00 43.18  ? 102 ASP C O   1 
ATOM 2741 C CB  . ASP C 1 103 ? 247.718 273.076 393.731 1.00 43.18  ? 102 ASP C CB  1 
ATOM 2742 C CG  . ASP C 1 103 ? 249.033 273.618 394.234 1.00 43.18  ? 102 ASP C CG  1 
ATOM 2743 O OD1 . ASP C 1 103 ? 250.089 273.220 393.706 1.00 43.18  ? 102 ASP C OD1 1 
ATOM 2744 O OD2 . ASP C 1 103 ? 249.012 274.443 395.172 1.00 43.18  ? 102 ASP C OD2 1 
ATOM 2745 N N   . GLU C 1 104 ? 247.397 269.896 393.870 1.00 42.46  ? 103 GLU C N   1 
ATOM 2746 C CA  . GLU C 1 104 ? 247.750 268.664 394.556 1.00 42.46  ? 103 GLU C CA  1 
ATOM 2747 C C   . GLU C 1 104 ? 248.118 267.546 393.600 1.00 42.46  ? 103 GLU C C   1 
ATOM 2748 O O   . GLU C 1 104 ? 248.803 266.606 394.005 1.00 42.46  ? 103 GLU C O   1 
ATOM 2749 C CB  . GLU C 1 104 ? 246.596 268.217 395.441 1.00 42.46  ? 103 GLU C CB  1 
ATOM 2750 C CG  . GLU C 1 104 ? 246.296 269.195 396.544 1.00 42.46  ? 103 GLU C CG  1 
ATOM 2751 C CD  . GLU C 1 104 ? 245.115 268.771 397.382 1.00 42.46  ? 103 GLU C CD  1 
ATOM 2752 O OE1 . GLU C 1 104 ? 244.458 267.773 397.016 1.00 42.46  ? 103 GLU C OE1 1 
ATOM 2753 O OE2 . GLU C 1 104 ? 244.842 269.434 398.403 1.00 42.46  ? 103 GLU C OE2 1 
ATOM 2754 N N   . GLU C 1 105 ? 247.665 267.609 392.352 1.00 40.64  ? 104 GLU C N   1 
ATOM 2755 C CA  . GLU C 1 105 ? 248.090 266.624 391.371 1.00 40.64  ? 104 GLU C CA  1 
ATOM 2756 C C   . GLU C 1 105 ? 249.509 266.888 390.910 1.00 40.64  ? 104 GLU C C   1 
ATOM 2757 O O   . GLU C 1 105 ? 250.231 265.951 390.564 1.00 40.64  ? 104 GLU C O   1 
ATOM 2758 C CB  . GLU C 1 105 ? 247.154 266.641 390.171 1.00 40.64  ? 104 GLU C CB  1 
ATOM 2759 C CG  . GLU C 1 105 ? 245.732 266.305 390.508 1.00 40.64  ? 104 GLU C CG  1 
ATOM 2760 C CD  . GLU C 1 105 ? 244.831 266.382 389.302 1.00 40.64  ? 104 GLU C CD  1 
ATOM 2761 O OE1 . GLU C 1 105 ? 245.324 266.750 388.217 1.00 40.64  ? 104 GLU C OE1 1 
ATOM 2762 O OE2 . GLU C 1 105 ? 243.628 266.091 389.439 1.00 40.64  ? 104 GLU C OE2 1 
ATOM 2763 N N   . ARG C 1 106 ? 249.916 268.155 390.897 1.00 36.31  ? 105 ARG C N   1 
ATOM 2764 C CA  . ARG C 1 106 ? 251.282 268.506 390.545 1.00 36.31  ? 105 ARG C CA  1 
ATOM 2765 C C   . ARG C 1 106 ? 252.231 268.276 391.710 1.00 36.31  ? 105 ARG C C   1 
ATOM 2766 O O   . ARG C 1 106 ? 253.369 267.844 391.509 1.00 36.31  ? 105 ARG C O   1 
ATOM 2767 C CB  . ARG C 1 106 ? 251.349 269.961 390.097 1.00 36.31  ? 105 ARG C CB  1 
ATOM 2768 C CG  . ARG C 1 106 ? 250.607 270.262 388.816 1.00 36.31  ? 105 ARG C CG  1 
ATOM 2769 C CD  . ARG C 1 106 ? 250.959 271.643 388.305 1.00 36.31  ? 105 ARG C CD  1 
ATOM 2770 N NE  . ARG C 1 106 ? 250.573 272.683 389.245 1.00 36.31  ? 105 ARG C NE  1 
ATOM 2771 C CZ  . ARG C 1 106 ? 249.425 273.341 389.189 1.00 36.31  ? 105 ARG C CZ  1 
ATOM 2772 N NH1 . ARG C 1 106 ? 248.567 273.088 388.219 1.00 36.31  ? 105 ARG C NH1 1 
ATOM 2773 N NH2 . ARG C 1 106 ? 249.149 274.274 390.085 1.00 36.31  ? 105 ARG C NH2 1 
ATOM 2774 N N   . ALA C 1 107 ? 251.793 268.579 392.928 1.00 34.38  ? 106 ALA C N   1 
ATOM 2775 C CA  . ALA C 1 107 ? 252.629 268.384 394.102 1.00 34.38  ? 106 ALA C CA  1 
ATOM 2776 C C   . ALA C 1 107 ? 252.782 266.921 394.474 1.00 34.38  ? 106 ALA C C   1 
ATOM 2777 O O   . ALA C 1 107 ? 253.713 266.576 395.202 1.00 34.38  ? 106 ALA C O   1 
ATOM 2778 C CB  . ALA C 1 107 ? 252.060 269.154 395.290 1.00 34.38  ? 106 ALA C CB  1 
ATOM 2779 N N   . PHE C 1 108 ? 251.894 266.055 393.994 1.00 32.17  ? 107 PHE C N   1 
ATOM 2780 C CA  . PHE C 1 108 ? 252.041 264.632 394.258 1.00 32.17  ? 107 PHE C CA  1 
ATOM 2781 C C   . PHE C 1 108 ? 253.135 264.025 393.396 1.00 32.17  ? 107 PHE C C   1 
ATOM 2782 O O   . PHE C 1 108 ? 253.874 263.159 393.863 1.00 32.17  ? 107 PHE C O   1 
ATOM 2783 C CB  . PHE C 1 108 ? 250.716 263.917 394.018 1.00 32.17  ? 107 PHE C CB  1 
ATOM 2784 C CG  . PHE C 1 108 ? 250.741 262.464 394.365 1.00 32.17  ? 107 PHE C CG  1 
ATOM 2785 C CD1 . PHE C 1 108 ? 250.695 262.055 395.683 1.00 32.17  ? 107 PHE C CD1 1 
ATOM 2786 C CD2 . PHE C 1 108 ? 250.796 261.506 393.371 1.00 32.17  ? 107 PHE C CD2 1 
ATOM 2787 C CE1 . PHE C 1 108 ? 250.711 260.724 396.002 1.00 32.17  ? 107 PHE C CE1 1 
ATOM 2788 C CE2 . PHE C 1 108 ? 250.814 260.172 393.687 1.00 32.17  ? 107 PHE C CE2 1 
ATOM 2789 C CZ  . PHE C 1 108 ? 250.772 259.783 395.003 1.00 32.17  ? 107 PHE C CZ  1 
ATOM 2790 N N   . VAL C 1 109 ? 253.252 264.471 392.144 1.00 30.21  ? 108 VAL C N   1 
ATOM 2791 C CA  . VAL C 1 109 ? 254.274 263.955 391.239 1.00 30.21  ? 108 VAL C CA  1 
ATOM 2792 C C   . VAL C 1 109 ? 255.659 264.403 391.687 1.00 30.21  ? 108 VAL C C   1 
ATOM 2793 O O   . VAL C 1 109 ? 256.628 263.640 391.607 1.00 30.21  ? 108 VAL C O   1 
ATOM 2794 C CB  . VAL C 1 109 ? 253.960 264.403 389.801 1.00 30.21  ? 108 VAL C CB  1 
ATOM 2795 C CG1 . VAL C 1 109 ? 255.004 263.930 388.832 1.00 30.21  ? 108 VAL C CG1 1 
ATOM 2796 C CG2 . VAL C 1 109 ? 252.609 263.900 389.385 1.00 30.21  ? 108 VAL C CG2 1 
ATOM 2797 N N   . ARG C 1 110 ? 255.767 265.632 392.195 1.00 29.21  ? 109 ARG C N   1 
ATOM 2798 C CA  . ARG C 1 110 ? 257.053 266.156 392.643 1.00 29.21  ? 109 ARG C CA  1 
ATOM 2799 C C   . ARG C 1 110 ? 257.550 265.440 393.888 1.00 29.21  ? 109 ARG C C   1 
ATOM 2800 O O   . ARG C 1 110 ? 258.727 265.077 393.967 1.00 29.21  ? 109 ARG C O   1 
ATOM 2801 C CB  . ARG C 1 110 ? 256.937 267.646 392.923 1.00 29.21  ? 109 ARG C CB  1 
ATOM 2802 C CG  . ARG C 1 110 ? 258.215 268.274 393.383 1.00 29.21  ? 109 ARG C CG  1 
ATOM 2803 C CD  . ARG C 1 110 ? 257.980 269.693 393.801 1.00 29.21  ? 109 ARG C CD  1 
ATOM 2804 N NE  . ARG C 1 110 ? 257.010 269.765 394.883 1.00 29.21  ? 109 ARG C NE  1 
ATOM 2805 C CZ  . ARG C 1 110 ? 257.291 269.573 396.165 1.00 29.21  ? 109 ARG C CZ  1 
ATOM 2806 N NH1 . ARG C 1 110 ? 258.528 269.303 396.546 1.00 29.21  ? 109 ARG C NH1 1 
ATOM 2807 N NH2 . ARG C 1 110 ? 256.331 269.662 397.072 1.00 29.21  ? 109 ARG C NH2 1 
ATOM 2808 N N   . THR C 1 111 ? 256.681 265.233 394.872 1.00 29.59  ? 110 THR C N   1 
ATOM 2809 C CA  . THR C 1 111 ? 257.092 264.532 396.079 1.00 29.59  ? 110 THR C CA  1 
ATOM 2810 C C   . THR C 1 111 ? 257.196 263.029 395.881 1.00 29.59  ? 110 THR C C   1 
ATOM 2811 O O   . THR C 1 111 ? 257.767 262.349 396.734 1.00 29.59  ? 110 THR C O   1 
ATOM 2812 C CB  . THR C 1 111 ? 256.124 264.825 397.220 1.00 29.59  ? 110 THR C CB  1 
ATOM 2813 O OG1 . THR C 1 111 ? 254.811 264.403 396.846 1.00 29.59  ? 110 THR C OG1 1 
ATOM 2814 C CG2 . THR C 1 111 ? 256.100 266.293 397.518 1.00 29.59  ? 110 THR C CG2 1 
ATOM 2815 N N   . GLU C 1 112 ? 256.642 262.492 394.797 1.00 29.49  ? 111 GLU C N   1 
ATOM 2816 C CA  . GLU C 1 112 ? 256.849 261.084 394.488 1.00 29.49  ? 111 GLU C CA  1 
ATOM 2817 C C   . GLU C 1 112 ? 258.223 260.856 393.886 1.00 29.49  ? 111 GLU C C   1 
ATOM 2818 O O   . GLU C 1 112 ? 258.933 259.926 394.281 1.00 29.49  ? 111 GLU C O   1 
ATOM 2819 C CB  . GLU C 1 112 ? 255.779 260.587 393.525 1.00 29.49  ? 111 GLU C CB  1 
ATOM 2820 C CG  . GLU C 1 112 ? 255.885 259.134 393.163 1.00 29.49  ? 111 GLU C CG  1 
ATOM 2821 C CD  . GLU C 1 112 ? 254.799 258.719 392.200 1.00 29.49  ? 111 GLU C CD  1 
ATOM 2822 O OE1 . GLU C 1 112 ? 253.998 259.590 391.812 1.00 29.49  ? 111 GLU C OE1 1 
ATOM 2823 O OE2 . GLU C 1 112 ? 254.740 257.529 391.837 1.00 29.49  ? 111 GLU C OE2 1 
ATOM 2824 N N   . LEU C 1 113 ? 258.597 261.685 392.907 1.00 27.42  ? 112 LEU C N   1 
ATOM 2825 C CA  . LEU C 1 113 ? 259.921 261.609 392.302 1.00 27.42  ? 112 LEU C CA  1 
ATOM 2826 C C   . LEU C 1 113 ? 261.012 261.910 393.315 1.00 27.42  ? 112 LEU C C   1 
ATOM 2827 O O   . LEU C 1 113 ? 262.081 261.301 393.274 1.00 27.42  ? 112 LEU C O   1 
ATOM 2828 C CB  . LEU C 1 113 ? 260.007 262.582 391.129 1.00 27.42  ? 112 LEU C CB  1 
ATOM 2829 C CG  . LEU C 1 113 ? 261.296 262.583 390.313 1.00 27.42  ? 112 LEU C CG  1 
ATOM 2830 C CD1 . LEU C 1 113 ? 261.469 261.258 389.621 1.00 27.42  ? 112 LEU C CD1 1 
ATOM 2831 C CD2 . LEU C 1 113 ? 261.292 263.703 389.306 1.00 27.42  ? 112 LEU C CD2 1 
ATOM 2832 N N   . ALA C 1 114 ? 260.748 262.816 394.251 1.00 28.51  ? 113 ALA C N   1 
ATOM 2833 C CA  . ALA C 1 114 ? 261.710 263.130 395.295 1.00 28.51  ? 113 ALA C CA  1 
ATOM 2834 C C   . ALA C 1 114 ? 261.796 262.056 396.364 1.00 28.51  ? 113 ALA C C   1 
ATOM 2835 O O   . ALA C 1 114 ? 262.738 262.075 397.160 1.00 28.51  ? 113 ALA C O   1 
ATOM 2836 C CB  . ALA C 1 114 ? 261.363 264.462 395.950 1.00 28.51  ? 113 ALA C CB  1 
ATOM 2837 N N   . ALA C 1 115 ? 260.836 261.140 396.418 1.00 29.61  ? 114 ALA C N   1 
ATOM 2838 C CA  . ALA C 1 115 ? 260.885 260.035 397.362 1.00 29.61  ? 114 ALA C CA  1 
ATOM 2839 C C   . ALA C 1 115 ? 261.268 258.719 396.714 1.00 29.61  ? 114 ALA C C   1 
ATOM 2840 O O   . ALA C 1 115 ? 261.564 257.761 397.430 1.00 29.61  ? 114 ALA C O   1 
ATOM 2841 C CB  . ALA C 1 115 ? 259.537 259.872 398.066 1.00 29.61  ? 114 ALA C CB  1 
ATOM 2842 N N   . LEU C 1 116 ? 261.232 258.641 395.385 1.00 29.82  ? 115 LEU C N   1 
ATOM 2843 C CA  . LEU C 1 116 ? 261.810 257.497 394.693 1.00 29.82  ? 115 LEU C CA  1 
ATOM 2844 C C   . LEU C 1 116 ? 263.321 257.569 394.682 1.00 29.82  ? 115 LEU C C   1 
ATOM 2845 O O   . LEU C 1 116 ? 263.992 256.537 394.710 1.00 29.82  ? 115 LEU C O   1 
ATOM 2846 C CB  . LEU C 1 116 ? 261.310 257.430 393.260 1.00 29.82  ? 115 LEU C CB  1 
ATOM 2847 C CG  . LEU C 1 116 ? 259.890 256.989 392.997 1.00 29.82  ? 115 LEU C CG  1 
ATOM 2848 C CD1 . LEU C 1 116 ? 259.601 257.205 391.542 1.00 29.82  ? 115 LEU C CD1 1 
ATOM 2849 C CD2 . LEU C 1 116 ? 259.787 255.532 393.342 1.00 29.82  ? 115 LEU C CD2 1 
ATOM 2850 N N   . LEU C 1 117 ? 263.869 258.775 394.627 1.00 28.60  ? 116 LEU C N   1 
ATOM 2851 C CA  . LEU C 1 117 ? 265.308 258.961 394.581 1.00 28.60  ? 116 LEU C CA  1 
ATOM 2852 C C   . LEU C 1 117 ? 265.977 258.731 395.925 1.00 28.60  ? 116 LEU C C   1 
ATOM 2853 O O   . LEU C 1 117 ? 267.206 258.669 395.981 1.00 28.60  ? 116 LEU C O   1 
ATOM 2854 C CB  . LEU C 1 117 ? 265.617 260.363 394.067 1.00 28.60  ? 116 LEU C CB  1 
ATOM 2855 C CG  . LEU C 1 117 ? 265.249 260.578 392.602 1.00 28.60  ? 116 LEU C CG  1 
ATOM 2856 C CD1 . LEU C 1 117 ? 265.373 262.024 392.222 1.00 28.60  ? 116 LEU C CD1 1 
ATOM 2857 C CD2 . LEU C 1 117 ? 266.132 259.740 391.723 1.00 28.60  ? 116 LEU C CD2 1 
ATOM 2858 N N   . ALA C 1 118 ? 265.208 258.616 397.000 1.00 31.59  ? 117 ALA C N   1 
ATOM 2859 C CA  . ALA C 1 118 ? 265.717 258.174 398.286 1.00 31.59  ? 117 ALA C CA  1 
ATOM 2860 C C   . ALA C 1 118 ? 265.359 256.728 398.587 1.00 31.59  ? 117 ALA C C   1 
ATOM 2861 O O   . ALA C 1 118 ? 265.801 256.192 399.604 1.00 31.59  ? 117 ALA C O   1 
ATOM 2862 C CB  . ALA C 1 118 ? 265.191 259.078 399.398 1.00 31.59  ? 117 ALA C CB  1 
ATOM 2863 N N   . SER C 1 119 ? 264.574 256.093 397.731 1.00 34.47  ? 118 SER C N   1 
ATOM 2864 C CA  . SER C 1 119 ? 264.186 254.703 397.881 1.00 34.47  ? 118 SER C CA  1 
ATOM 2865 C C   . SER C 1 119 ? 265.337 253.791 397.461 1.00 34.47  ? 118 SER C C   1 
ATOM 2866 O O   . SER C 1 119 ? 266.146 254.167 396.612 1.00 34.47  ? 118 SER C O   1 
ATOM 2867 C CB  . SER C 1 119 ? 262.959 254.413 397.030 1.00 34.47  ? 118 SER C CB  1 
ATOM 2868 O OG  . SER C 1 119 ? 263.286 254.508 395.660 1.00 34.47  ? 118 SER C OG  1 
ATOM 2869 N N   . PRO C 1 120 ? 265.438 252.586 398.037 1.00 36.66  ? 119 PRO C N   1 
ATOM 2870 C CA  . PRO C 1 120 ? 266.569 251.707 397.696 1.00 36.66  ? 119 PRO C CA  1 
ATOM 2871 C C   . PRO C 1 120 ? 266.490 251.074 396.318 1.00 36.66  ? 119 PRO C C   1 
ATOM 2872 O O   . PRO C 1 120 ? 267.453 250.414 395.913 1.00 36.66  ? 119 PRO C O   1 
ATOM 2873 C CB  . PRO C 1 120 ? 266.525 250.643 398.790 1.00 36.66  ? 119 PRO C CB  1 
ATOM 2874 C CG  . PRO C 1 120 ? 265.130 250.619 399.219 1.00 36.66  ? 119 PRO C CG  1 
ATOM 2875 C CD  . PRO C 1 120 ? 264.642 252.023 399.137 1.00 36.66  ? 119 PRO C CD  1 
ATOM 2876 N N   . LEU C 1 121 ? 265.388 251.244 395.589 1.00 37.40  ? 120 LEU C N   1 
ATOM 2877 C CA  . LEU C 1 121 ? 265.368 250.850 394.187 1.00 37.40  ? 120 LEU C CA  1 
ATOM 2878 C C   . LEU C 1 121 ? 266.272 251.744 393.352 1.00 37.40  ? 120 LEU C C   1 
ATOM 2879 O O   . LEU C 1 121 ? 267.004 251.254 392.487 1.00 37.40  ? 120 LEU C O   1 
ATOM 2880 C CB  . LEU C 1 121 ? 263.941 250.898 393.652 1.00 37.40  ? 120 LEU C CB  1 
ATOM 2881 C CG  . LEU C 1 121 ? 263.766 250.549 392.179 1.00 37.40  ? 120 LEU C CG  1 
ATOM 2882 C CD1 . LEU C 1 121 ? 264.163 249.112 391.924 1.00 37.40  ? 120 LEU C CD1 1 
ATOM 2883 C CD2 . LEU C 1 121 ? 262.340 250.795 391.759 1.00 37.40  ? 120 LEU C CD2 1 
ATOM 2884 N N   . LEU C 1 122 ? 266.238 253.053 393.593 1.00 35.66  ? 121 LEU C N   1 
ATOM 2885 C CA  . LEU C 1 122 ? 266.946 254.005 392.751 1.00 35.66  ? 121 LEU C CA  1 
ATOM 2886 C C   . LEU C 1 122 ? 268.236 254.533 393.356 1.00 35.66  ? 121 LEU C C   1 
ATOM 2887 O O   . LEU C 1 122 ? 269.001 255.183 392.643 1.00 35.66  ? 121 LEU C O   1 
ATOM 2888 C CB  . LEU C 1 122 ? 266.045 255.184 392.395 1.00 35.66  ? 121 LEU C CB  1 
ATOM 2889 C CG  . LEU C 1 122 ? 264.913 254.855 391.439 1.00 35.66  ? 121 LEU C CG  1 
ATOM 2890 C CD1 . LEU C 1 122 ? 264.072 256.074 391.231 1.00 35.66  ? 121 LEU C CD1 1 
ATOM 2891 C CD2 . LEU C 1 122 ? 265.478 254.398 390.127 1.00 35.66  ? 121 LEU C CD2 1 
ATOM 2892 N N   . ILE C 1 123 ? 268.527 254.256 394.632 1.00 36.42  ? 122 ILE C N   1 
ATOM 2893 C CA  . ILE C 1 123 ? 269.900 254.447 395.095 1.00 36.42  ? 122 ILE C CA  1 
ATOM 2894 C C   . ILE C 1 123 ? 270.770 253.264 394.720 1.00 36.42  ? 122 ILE C C   1 
ATOM 2895 O O   . ILE C 1 123 ? 271.975 253.278 394.992 1.00 36.42  ? 122 ILE C O   1 
ATOM 2896 C CB  . ILE C 1 123 ? 270.050 254.666 396.615 1.00 36.42  ? 122 ILE C CB  1 
ATOM 2897 C CG1 . ILE C 1 123 ? 269.798 253.386 397.392 1.00 36.42  ? 122 ILE C CG1 1 
ATOM 2898 C CG2 . ILE C 1 123 ? 269.095 255.719 397.106 1.00 36.42  ? 122 ILE C CG2 1 
ATOM 2899 C CD1 . ILE C 1 123 ? 270.186 253.493 398.848 1.00 36.42  ? 122 ILE C CD1 1 
ATOM 2900 N N   . ASP C 1 124 ? 270.189 252.235 394.103 1.00 38.44  ? 123 ASP C N   1 
ATOM 2901 C CA  . ASP C 1 124 ? 270.908 251.085 393.589 1.00 38.44  ? 123 ASP C CA  1 
ATOM 2902 C C   . ASP C 1 124 ? 270.875 251.000 392.073 1.00 38.44  ? 123 ASP C C   1 
ATOM 2903 O O   . ASP C 1 124 ? 271.730 250.334 391.490 1.00 38.44  ? 123 ASP C O   1 
ATOM 2904 C CB  . ASP C 1 124 ? 270.327 249.799 394.191 1.00 38.44  ? 123 ASP C CB  1 
ATOM 2905 C CG  . ASP C 1 124 ? 271.210 248.598 393.976 1.00 38.44  ? 123 ASP C CG  1 
ATOM 2906 O OD1 . ASP C 1 124 ? 272.267 248.513 394.634 1.00 38.44  ? 123 ASP C OD1 1 
ATOM 2907 O OD2 . ASP C 1 124 ? 270.840 247.728 393.166 1.00 38.44  ? 123 ASP C OD2 1 
ATOM 2908 N N   . ALA C 1 125 ? 269.943 251.690 391.421 1.00 36.64  ? 124 ALA C N   1 
ATOM 2909 C CA  . ALA C 1 125 ? 269.890 251.728 389.969 1.00 36.64  ? 124 ALA C CA  1 
ATOM 2910 C C   . ALA C 1 125 ? 270.743 252.828 389.373 1.00 36.64  ? 124 ALA C C   1 
ATOM 2911 O O   . ALA C 1 125 ? 270.924 252.857 388.153 1.00 36.64  ? 124 ALA C O   1 
ATOM 2912 C CB  . ALA C 1 125 ? 268.452 251.915 389.489 1.00 36.64  ? 124 ALA C CB  1 
ATOM 2913 N N   . ILE C 1 126 ? 271.248 253.742 390.192 1.00 35.83  ? 125 ILE C N   1 
ATOM 2914 C CA  . ILE C 1 126 ? 272.044 254.869 389.732 1.00 35.83  ? 125 ILE C CA  1 
ATOM 2915 C C   . ILE C 1 126 ? 273.442 254.839 390.336 1.00 35.83  ? 125 ILE C C   1 
ATOM 2916 O O   . ILE C 1 126 ? 274.435 254.991 389.626 1.00 35.83  ? 125 ILE C O   1 
ATOM 2917 C CB  . ILE C 1 126 ? 271.336 256.205 390.041 1.00 35.83  ? 125 ILE C CB  1 
ATOM 2918 C CG1 . ILE C 1 126 ? 269.994 256.266 389.330 1.00 35.83  ? 125 ILE C CG1 1 
ATOM 2919 C CG2 . ILE C 1 126 ? 272.160 257.372 389.576 1.00 35.83  ? 125 ILE C CG2 1 
ATOM 2920 C CD1 . ILE C 1 126 ? 269.152 257.428 389.750 1.00 35.83  ? 125 ILE C CD1 1 
ATOM 2921 N N   . ASP C 1 127 ? 273.537 254.626 391.649 1.00 37.82  ? 126 ASP C N   1 
ATOM 2922 C CA  . ASP C 1 127 ? 274.840 254.633 392.305 1.00 37.82  ? 126 ASP C CA  1 
ATOM 2923 C C   . ASP C 1 127 ? 275.668 253.407 391.942 1.00 37.82  ? 126 ASP C C   1 
ATOM 2924 O O   . ASP C 1 127 ? 276.882 253.513 391.744 1.00 37.82  ? 126 ASP C O   1 
ATOM 2925 C CB  . ASP C 1 127 ? 274.668 254.712 393.816 1.00 37.82  ? 126 ASP C CB  1 
ATOM 2926 C CG  . ASP C 1 127 ? 274.172 256.052 394.265 1.00 37.82  ? 126 ASP C CG  1 
ATOM 2927 O OD1 . ASP C 1 127 ? 274.439 257.037 393.556 1.00 37.82  ? 126 ASP C OD1 1 
ATOM 2928 O OD2 . ASP C 1 127 ? 273.526 256.127 395.327 1.00 37.82  ? 126 ASP C OD2 1 
ATOM 2929 N N   . GLN C 1 128 ? 275.040 252.240 391.860 1.00 40.70  ? 127 GLN C N   1 
ATOM 2930 C CA  . GLN C 1 128 ? 275.756 251.012 391.554 1.00 40.70  ? 127 GLN C CA  1 
ATOM 2931 C C   . GLN C 1 128 ? 275.518 250.522 390.135 1.00 40.70  ? 127 GLN C C   1 
ATOM 2932 O O   . GLN C 1 128 ? 276.150 249.541 389.733 1.00 40.70  ? 127 GLN C O   1 
ATOM 2933 C CB  . GLN C 1 128 ? 275.353 249.911 392.538 1.00 40.70  ? 127 GLN C CB  1 
ATOM 2934 C CG  . GLN C 1 128 ? 275.635 250.245 393.983 1.00 40.70  ? 127 GLN C CG  1 
ATOM 2935 C CD  . GLN C 1 128 ? 277.101 250.450 394.259 1.00 40.70  ? 127 GLN C CD  1 
ATOM 2936 O OE1 . GLN C 1 128 ? 277.545 251.565 394.525 1.00 40.70  ? 127 GLN C OE1 1 
ATOM 2937 N NE2 . GLN C 1 128 ? 277.868 249.372 394.197 1.00 40.70  ? 127 GLN C NE2 1 
ATOM 2938 N N   . LEU C 1 129 ? 274.606 251.165 389.399 1.00 38.94  ? 128 LEU C N   1 
ATOM 2939 C CA  . LEU C 1 129 ? 274.240 250.837 388.015 1.00 38.94  ? 128 LEU C CA  1 
ATOM 2940 C C   . LEU C 1 129 ? 273.682 249.421 387.883 1.00 38.94  ? 128 LEU C C   1 
ATOM 2941 O O   . LEU C 1 129 ? 273.982 248.707 386.926 1.00 38.94  ? 128 LEU C O   1 
ATOM 2942 C CB  . LEU C 1 129 ? 275.405 251.054 387.047 1.00 38.94  ? 128 LEU C CB  1 
ATOM 2943 C CG  . LEU C 1 129 ? 275.855 252.496 386.860 1.00 38.94  ? 128 LEU C CG  1 
ATOM 2944 C CD1 . LEU C 1 129 ? 277.097 252.550 386.013 1.00 38.94  ? 128 LEU C CD1 1 
ATOM 2945 C CD2 . LEU C 1 129 ? 274.752 253.317 386.235 1.00 38.94  ? 128 LEU C CD2 1 
ATOM 2946 N N   . ASN C 1 130 ? 272.845 249.017 388.833 1.00 41.20  ? 129 ASN C N   1 
ATOM 2947 C CA  . ASN C 1 130 ? 272.189 247.719 388.764 1.00 41.20  ? 129 ASN C CA  1 
ATOM 2948 C C   . ASN C 1 130 ? 270.816 247.871 388.134 1.00 41.20  ? 129 ASN C C   1 
ATOM 2949 O O   . ASN C 1 130 ? 269.966 248.569 388.699 1.00 41.20  ? 129 ASN C O   1 
ATOM 2950 C CB  . ASN C 1 130 ? 272.032 247.113 390.143 1.00 41.20  ? 129 ASN C CB  1 
ATOM 2951 C CG  . ASN C 1 130 ? 273.345 246.791 390.789 1.00 41.20  ? 129 ASN C CG  1 
ATOM 2952 O OD1 . ASN C 1 130 ? 274.287 246.377 390.125 1.00 41.20  ? 129 ASN C OD1 1 
ATOM 2953 N ND2 . ASN C 1 130 ? 273.409 246.946 392.102 1.00 41.20  ? 129 ASN C ND2 1 
ATOM 2954 N N   . PRO C 1 131 ? 270.540 247.235 387.000 1.00 43.06  ? 130 PRO C N   1 
ATOM 2955 C CA  . PRO C 1 131 ? 269.177 247.253 386.470 1.00 43.06  ? 130 PRO C CA  1 
ATOM 2956 C C   . PRO C 1 131 ? 268.249 246.416 387.329 1.00 43.06  ? 130 PRO C C   1 
ATOM 2957 O O   . PRO C 1 131 ? 268.620 245.344 387.809 1.00 43.06  ? 130 PRO C O   1 
ATOM 2958 C CB  . PRO C 1 131 ? 269.331 246.646 385.073 1.00 43.06  ? 130 PRO C CB  1 
ATOM 2959 C CG  . PRO C 1 131 ? 270.749 246.821 384.740 1.00 43.06  ? 130 PRO C CG  1 
ATOM 2960 C CD  . PRO C 1 131 ? 271.490 246.684 386.024 1.00 43.06  ? 130 PRO C CD  1 
ATOM 2961 N N   . ALA C 1 132 ? 267.039 246.922 387.534 1.00 45.18  ? 131 ALA C N   1 
ATOM 2962 C CA  . ALA C 1 132 ? 266.036 246.157 388.254 1.00 45.18  ? 131 ALA C CA  1 
ATOM 2963 C C   . ALA C 1 132 ? 265.523 245.024 387.381 1.00 45.18  ? 131 ALA C C   1 
ATOM 2964 O O   . ALA C 1 132 ? 265.310 245.194 386.179 1.00 45.18  ? 131 ALA C O   1 
ATOM 2965 C CB  . ALA C 1 132 ? 264.883 247.057 388.682 1.00 45.18  ? 131 ALA C CB  1 
ATOM 2966 N N   . TYR C 1 133 ? 265.339 243.858 387.986 1.00 47.14  ? 132 TYR C N   1 
ATOM 2967 C CA  . TYR C 1 133 ? 264.957 242.675 387.232 1.00 47.14  ? 132 TYR C CA  1 
ATOM 2968 C C   . TYR C 1 133 ? 263.879 241.890 387.966 1.00 47.14  ? 132 TYR C C   1 
ATOM 2969 O O   . TYR C 1 133 ? 263.897 241.791 389.192 1.00 47.14  ? 132 TYR C O   1 
ATOM 2970 C CB  . TYR C 1 133 ? 266.185 241.792 386.959 1.00 47.14  ? 132 TYR C CB  1 
ATOM 2971 C CG  . TYR C 1 133 ? 266.840 241.218 388.195 1.00 47.14  ? 132 TYR C CG  1 
ATOM 2972 C CD1 . TYR C 1 133 ? 267.783 241.944 388.908 1.00 47.14  ? 132 TYR C CD1 1 
ATOM 2973 C CD2 . TYR C 1 133 ? 266.545 239.933 388.628 1.00 47.14  ? 132 TYR C CD2 1 
ATOM 2974 C CE1 . TYR C 1 133 ? 268.381 241.426 390.030 1.00 47.14  ? 132 TYR C CE1 1 
ATOM 2975 C CE2 . TYR C 1 133 ? 267.145 239.406 389.750 1.00 47.14  ? 132 TYR C CE2 1 
ATOM 2976 C CZ  . TYR C 1 133 ? 268.060 240.158 390.445 1.00 47.14  ? 132 TYR C CZ  1 
ATOM 2977 O OH  . TYR C 1 133 ? 268.663 239.639 391.562 1.00 47.14  ? 132 TYR C OH  1 
ATOM 2978 N N   . GLU D 2 4   ? 269.122 282.446 403.179 1.00 76.50  ? 4   GLU H N   1 
ATOM 2979 C CA  . GLU D 2 4   ? 268.993 283.531 404.141 1.00 76.50  ? 4   GLU H CA  1 
ATOM 2980 C C   . GLU D 2 4   ? 270.331 283.853 404.792 1.00 76.50  ? 4   GLU H C   1 
ATOM 2981 O O   . GLU D 2 4   ? 271.201 282.995 404.914 1.00 76.50  ? 4   GLU H O   1 
ATOM 2982 C CB  . GLU D 2 4   ? 267.956 283.178 405.208 1.00 76.50  ? 4   GLU H CB  1 
ATOM 2983 C CG  . GLU D 2 4   ? 268.317 281.966 406.046 1.00 76.50  ? 4   GLU H CG  1 
ATOM 2984 C CD  . GLU D 2 4   ? 267.260 281.620 407.071 1.00 76.50  ? 4   GLU H CD  1 
ATOM 2985 O OE1 . GLU D 2 4   ? 266.229 282.324 407.126 1.00 76.50  ? 4   GLU H OE1 1 
ATOM 2986 O OE2 . GLU D 2 4   ? 267.461 280.641 407.822 1.00 76.50  ? 4   GLU H OE2 1 
ATOM 2987 N N   . VAL D 2 5   ? 270.491 285.105 405.203 1.00 72.45  ? 5   VAL H N   1 
ATOM 2988 C CA  . VAL D 2 5   ? 271.723 285.554 405.837 1.00 72.45  ? 5   VAL H CA  1 
ATOM 2989 C C   . VAL D 2 5   ? 271.731 285.050 407.274 1.00 72.45  ? 5   VAL H C   1 
ATOM 2990 O O   . VAL D 2 5   ? 270.813 285.333 408.047 1.00 72.45  ? 5   VAL H O   1 
ATOM 2991 C CB  . VAL D 2 5   ? 271.838 287.082 405.779 1.00 72.45  ? 5   VAL H CB  1 
ATOM 2992 C CG1 . VAL D 2 5   ? 273.073 287.552 406.498 1.00 72.45  ? 5   VAL H CG1 1 
ATOM 2993 C CG2 . VAL D 2 5   ? 271.851 287.548 404.339 1.00 72.45  ? 5   VAL H CG2 1 
ATOM 2994 N N   . GLN D 2 6   ? 272.761 284.287 407.630 1.00 73.76  ? 6   GLN H N   1 
ATOM 2995 C CA  . GLN D 2 6   ? 272.839 283.673 408.943 1.00 73.76  ? 6   GLN H CA  1 
ATOM 2996 C C   . GLN D 2 6   ? 274.256 283.811 409.473 1.00 73.76  ? 6   GLN H C   1 
ATOM 2997 O O   . GLN D 2 6   ? 275.221 283.613 408.733 1.00 73.76  ? 6   GLN H O   1 
ATOM 2998 C CB  . GLN D 2 6   ? 272.428 282.199 408.881 1.00 73.76  ? 6   GLN H CB  1 
ATOM 2999 C CG  . GLN D 2 6   ? 272.305 281.520 410.225 1.00 73.76  ? 6   GLN H CG  1 
ATOM 3000 C CD  . GLN D 2 6   ? 271.861 280.085 410.100 1.00 73.76  ? 6   GLN H CD  1 
ATOM 3001 O OE1 . GLN D 2 6   ? 271.682 279.576 408.995 1.00 73.76  ? 6   GLN H OE1 1 
ATOM 3002 N NE2 . GLN D 2 6   ? 271.681 279.418 411.232 1.00 73.76  ? 6   GLN H NE2 1 
ATOM 3003 N N   . LEU D 2 7   ? 274.375 284.158 410.752 1.00 74.74  ? 7   LEU H N   1 
ATOM 3004 C CA  . LEU D 2 7   ? 275.665 284.422 411.384 1.00 74.74  ? 7   LEU H CA  1 
ATOM 3005 C C   . LEU D 2 7   ? 275.664 283.670 412.711 1.00 74.74  ? 7   LEU H C   1 
ATOM 3006 O O   . LEU D 2 7   ? 275.085 284.146 413.692 1.00 74.74  ? 7   LEU H O   1 
ATOM 3007 C CB  . LEU D 2 7   ? 275.881 285.919 411.608 1.00 74.74  ? 7   LEU H CB  1 
ATOM 3008 C CG  . LEU D 2 7   ? 276.127 286.949 410.490 1.00 74.74  ? 7   LEU H CG  1 
ATOM 3009 C CD1 . LEU D 2 7   ? 277.245 286.556 409.545 1.00 74.74  ? 7   LEU H CD1 1 
ATOM 3010 C CD2 . LEU D 2 7   ? 274.878 287.321 409.725 1.00 74.74  ? 7   LEU H CD2 1 
ATOM 3011 N N   . VAL D 2 8   ? 276.300 282.505 412.756 1.00 75.26  ? 8   VAL H N   1 
ATOM 3012 C CA  . VAL D 2 8   ? 276.303 281.662 413.947 1.00 75.26  ? 8   VAL H CA  1 
ATOM 3013 C C   . VAL D 2 8   ? 277.661 281.807 414.620 1.00 75.26  ? 8   VAL H C   1 
ATOM 3014 O O   . VAL D 2 8   ? 278.681 281.358 414.085 1.00 75.26  ? 8   VAL H O   1 
ATOM 3015 C CB  . VAL D 2 8   ? 276.007 280.195 413.610 1.00 75.26  ? 8   VAL H CB  1 
ATOM 3016 C CG1 . VAL D 2 8   ? 276.102 279.349 414.857 1.00 75.26  ? 8   VAL H CG1 1 
ATOM 3017 C CG2 . VAL D 2 8   ? 274.639 280.061 412.976 1.00 75.26  ? 8   VAL H CG2 1 
ATOM 3018 N N   . GLU D 2 9   ? 277.679 282.419 415.801 1.00 80.17  ? 9   GLU H N   1 
ATOM 3019 C CA  . GLU D 2 9   ? 278.922 282.690 416.504 1.00 80.17  ? 9   GLU H CA  1 
ATOM 3020 C C   . GLU D 2 9   ? 279.334 281.501 417.364 1.00 80.17  ? 9   GLU H C   1 
ATOM 3021 O O   . GLU D 2 9   ? 278.575 280.554 417.573 1.00 80.17  ? 9   GLU H O   1 
ATOM 3022 C CB  . GLU D 2 9   ? 278.794 283.930 417.388 1.00 80.17  ? 9   GLU H CB  1 
ATOM 3023 C CG  . GLU D 2 9   ? 278.512 285.228 416.668 1.00 80.17  ? 9   GLU H CG  1 
ATOM 3024 C CD  . GLU D 2 9   ? 277.031 285.466 416.477 1.00 80.17  ? 9   GLU H CD  1 
ATOM 3025 O OE1 . GLU D 2 9   ? 276.230 284.631 416.940 1.00 80.17  ? 9   GLU H OE1 1 
ATOM 3026 O OE2 . GLU D 2 9   ? 276.663 286.492 415.878 1.00 80.17  ? 9   GLU H OE2 1 
ATOM 3027 N N   . SER D 2 10  ? 280.556 281.571 417.888 1.00 82.83  ? 10  SER H N   1 
ATOM 3028 C CA  . SER D 2 10  ? 281.064 280.561 418.801 1.00 82.83  ? 10  SER H CA  1 
ATOM 3029 C C   . SER D 2 10  ? 282.102 281.201 419.710 1.00 82.83  ? 10  SER H C   1 
ATOM 3030 O O   . SER D 2 10  ? 282.504 282.349 419.516 1.00 82.83  ? 10  SER H O   1 
ATOM 3031 C CB  . SER D 2 10  ? 281.659 279.369 418.051 1.00 82.83  ? 10  SER H CB  1 
ATOM 3032 O OG  . SER D 2 10  ? 282.828 279.749 417.354 1.00 82.83  ? 10  SER H OG  1 
ATOM 3033 N N   . GLY D 2 11  ? 282.534 280.441 420.710 1.00 87.14  ? 11  GLY H N   1 
ATOM 3034 C CA  . GLY D 2 11  ? 283.482 280.938 421.687 1.00 87.14  ? 11  GLY H CA  1 
ATOM 3035 C C   . GLY D 2 11  ? 282.831 281.220 423.024 1.00 87.14  ? 11  GLY H C   1 
ATOM 3036 O O   . GLY D 2 11  ? 281.931 280.489 423.446 1.00 87.14  ? 11  GLY H O   1 
ATOM 3037 N N   . GLY D 2 12  ? 283.273 282.276 423.701 1.00 91.35  ? 12  GLY H N   1 
ATOM 3038 C CA  . GLY D 2 12  ? 282.659 282.653 424.959 1.00 91.35  ? 12  GLY H CA  1 
ATOM 3039 C C   . GLY D 2 12  ? 283.217 281.883 426.145 1.00 91.35  ? 12  GLY H C   1 
ATOM 3040 O O   . GLY D 2 12  ? 284.262 281.239 426.069 1.00 91.35  ? 12  GLY H O   1 
ATOM 3041 N N   . GLY D 2 13  ? 282.497 281.960 427.260 1.00 94.40  ? 13  GLY H N   1 
ATOM 3042 C CA  . GLY D 2 13  ? 282.877 281.260 428.471 1.00 94.40  ? 13  GLY H CA  1 
ATOM 3043 C C   . GLY D 2 13  ? 283.320 282.202 429.573 1.00 94.40  ? 13  GLY H C   1 
ATOM 3044 O O   . GLY D 2 13  ? 283.271 283.431 429.458 1.00 94.40  ? 13  GLY H O   1 
ATOM 3045 N N   . LEU D 2 14  ? 283.766 281.592 430.669 1.00 99.53  ? 14  LEU H N   1 
ATOM 3046 C CA  . LEU D 2 14  ? 284.197 282.306 431.866 1.00 99.53  ? 14  LEU H CA  1 
ATOM 3047 C C   . LEU D 2 14  ? 285.719 282.342 431.879 1.00 99.53  ? 14  LEU H C   1 
ATOM 3048 O O   . LEU D 2 14  ? 286.365 281.325 432.149 1.00 99.53  ? 14  LEU H O   1 
ATOM 3049 C CB  . LEU D 2 14  ? 283.660 281.629 433.125 1.00 99.53  ? 14  LEU H CB  1 
ATOM 3050 C CG  . LEU D 2 14  ? 282.142 281.580 433.307 1.00 99.53  ? 14  LEU H CG  1 
ATOM 3051 C CD1 . LEU D 2 14  ? 281.776 280.760 434.533 1.00 99.53  ? 14  LEU H CD1 1 
ATOM 3052 C CD2 . LEU D 2 14  ? 281.568 282.972 433.411 1.00 99.53  ? 14  LEU H CD2 1 
ATOM 3053 N N   . VAL D 2 15  ? 286.293 283.504 431.578 1.00 99.37  ? 15  VAL H N   1 
ATOM 3054 C CA  . VAL D 2 15  ? 287.740 283.683 431.528 1.00 99.37  ? 15  VAL H CA  1 
ATOM 3055 C C   . VAL D 2 15  ? 288.111 284.832 432.457 1.00 99.37  ? 15  VAL H C   1 
ATOM 3056 O O   . VAL D 2 15  ? 287.502 285.905 432.397 1.00 99.37  ? 15  VAL H O   1 
ATOM 3057 C CB  . VAL D 2 15  ? 288.230 283.956 430.093 1.00 99.37  ? 15  VAL H CB  1 
ATOM 3058 C CG1 . VAL D 2 15  ? 289.731 284.174 430.067 1.00 99.37  ? 15  VAL H CG1 1 
ATOM 3059 C CG2 . VAL D 2 15  ? 287.854 282.812 429.163 1.00 99.37  ? 15  VAL H CG2 1 
ATOM 3060 N N   . LYS D 2 16  ? 289.106 284.602 433.315 1.00 100.92 ? 16  LYS H N   1 
ATOM 3061 C CA  . LYS D 2 16  ? 289.590 285.630 434.223 1.00 100.92 ? 16  LYS H CA  1 
ATOM 3062 C C   . LYS D 2 16  ? 290.360 286.706 433.461 1.00 100.92 ? 16  LYS H C   1 
ATOM 3063 O O   . LYS D 2 16  ? 290.666 286.573 432.273 1.00 100.92 ? 16  LYS H O   1 
ATOM 3064 C CB  . LYS D 2 16  ? 290.478 285.016 435.303 1.00 100.92 ? 16  LYS H CB  1 
ATOM 3065 C CG  . LYS D 2 16  ? 289.730 284.164 436.313 1.00 100.92 ? 16  LYS H CG  1 
ATOM 3066 C CD  . LYS D 2 16  ? 290.692 283.466 437.254 1.00 100.92 ? 16  LYS H CD  1 
ATOM 3067 C CE  . LYS D 2 16  ? 291.355 284.460 438.192 1.00 100.92 ? 16  LYS H CE  1 
ATOM 3068 N NZ  . LYS D 2 16  ? 292.221 283.782 439.196 1.00 100.92 ? 16  LYS H NZ  1 
ATOM 3069 N N   . SER D 2 17  ? 290.686 287.783 434.173 1.00 100.15 ? 17  SER H N   1 
ATOM 3070 C CA  . SER D 2 17  ? 291.314 288.940 433.548 1.00 100.15 ? 17  SER H CA  1 
ATOM 3071 C C   . SER D 2 17  ? 292.755 288.640 433.157 1.00 100.15 ? 17  SER H C   1 
ATOM 3072 O O   . SER D 2 17  ? 293.445 287.856 433.814 1.00 100.15 ? 17  SER H O   1 
ATOM 3073 C CB  . SER D 2 17  ? 291.270 290.142 434.489 1.00 100.15 ? 17  SER H CB  1 
ATOM 3074 O OG  . SER D 2 17  ? 292.074 289.920 435.633 1.00 100.15 ? 17  SER H OG  1 
ATOM 3075 N N   . GLY D 2 18  ? 293.201 289.266 432.071 1.00 98.56  ? 18  GLY H N   1 
ATOM 3076 C CA  . GLY D 2 18  ? 294.533 289.061 431.552 1.00 98.56  ? 18  GLY H CA  1 
ATOM 3077 C C   . GLY D 2 18  ? 294.683 287.889 430.610 1.00 98.56  ? 18  GLY H C   1 
ATOM 3078 O O   . GLY D 2 18  ? 295.806 287.606 430.176 1.00 98.56  ? 18  GLY H O   1 
ATOM 3079 N N   . GLY D 2 19  ? 293.597 287.198 430.279 1.00 97.24  ? 19  GLY H N   1 
ATOM 3080 C CA  . GLY D 2 19  ? 293.651 286.018 429.442 1.00 97.24  ? 19  GLY H CA  1 
ATOM 3081 C C   . GLY D 2 19  ? 293.628 286.337 427.963 1.00 97.24  ? 19  GLY H C   1 
ATOM 3082 O O   . GLY D 2 19  ? 294.083 287.394 427.518 1.00 97.24  ? 19  GLY H O   1 
ATOM 3083 N N   . SER D 2 20  ? 293.092 285.395 427.190 1.00 92.34  ? 20  SER H N   1 
ATOM 3084 C CA  . SER D 2 20  ? 292.989 285.532 425.746 1.00 92.34  ? 20  SER H CA  1 
ATOM 3085 C C   . SER D 2 20  ? 291.848 284.667 425.234 1.00 92.34  ? 20  SER H C   1 
ATOM 3086 O O   . SER D 2 20  ? 291.491 283.659 425.848 1.00 92.34  ? 20  SER H O   1 
ATOM 3087 C CB  . SER D 2 20  ? 294.296 285.141 425.048 1.00 92.34  ? 20  SER H CB  1 
ATOM 3088 O OG  . SER D 2 20  ? 294.560 283.758 425.198 1.00 92.34  ? 20  SER H OG  1 
ATOM 3089 N N   . LEU D 2 21  ? 291.281 285.069 424.097 1.00 87.70  ? 21  LEU H N   1 
ATOM 3090 C CA  . LEU D 2 21  ? 290.186 284.339 423.474 1.00 87.70  ? 21  LEU H CA  1 
ATOM 3091 C C   . LEU D 2 21  ? 290.290 284.408 421.959 1.00 87.70  ? 21  LEU H C   1 
ATOM 3092 O O   . LEU D 2 21  ? 291.146 285.093 421.393 1.00 87.70  ? 21  LEU H O   1 
ATOM 3093 C CB  . LEU D 2 21  ? 288.816 284.877 423.898 1.00 87.70  ? 21  LEU H CB  1 
ATOM 3094 C CG  . LEU D 2 21  ? 288.283 284.535 425.281 1.00 87.70  ? 21  LEU H CG  1 
ATOM 3095 C CD1 . LEU D 2 21  ? 286.994 285.280 425.535 1.00 87.70  ? 21  LEU H CD1 1 
ATOM 3096 C CD2 . LEU D 2 21  ? 288.049 283.046 425.354 1.00 87.70  ? 21  LEU H CD2 1 
ATOM 3097 N N   . LYS D 2 22  ? 289.387 283.677 421.311 1.00 81.64  ? 22  LYS H N   1 
ATOM 3098 C CA  . LYS D 2 22  ? 289.163 283.755 419.876 1.00 81.64  ? 22  LYS H CA  1 
ATOM 3099 C C   . LYS D 2 22  ? 287.706 283.428 419.608 1.00 81.64  ? 22  LYS H C   1 
ATOM 3100 O O   . LYS D 2 22  ? 287.234 282.352 419.984 1.00 81.64  ? 22  LYS H O   1 
ATOM 3101 C CB  . LYS D 2 22  ? 290.062 282.790 419.099 1.00 81.64  ? 22  LYS H CB  1 
ATOM 3102 C CG  . LYS D 2 22  ? 289.790 282.810 417.604 1.00 81.64  ? 22  LYS H CG  1 
ATOM 3103 C CD  . LYS D 2 22  ? 290.653 281.825 416.855 1.00 81.64  ? 22  LYS H CD  1 
ATOM 3104 C CE  . LYS D 2 22  ? 292.065 282.343 416.709 1.00 81.64  ? 22  LYS H CE  1 
ATOM 3105 N NZ  . LYS D 2 22  ? 292.102 283.513 415.791 1.00 81.64  ? 22  LYS H NZ  1 
ATOM 3106 N N   . LEU D 2 23  ? 287.003 284.346 418.964 1.00 78.77  ? 23  LEU H N   1 
ATOM 3107 C CA  . LEU D 2 23  ? 285.634 284.120 418.539 1.00 78.77  ? 23  LEU H CA  1 
ATOM 3108 C C   . LEU D 2 23  ? 285.620 283.760 417.062 1.00 78.77  ? 23  LEU H C   1 
ATOM 3109 O O   . LEU D 2 23  ? 286.650 283.773 416.388 1.00 78.77  ? 23  LEU H O   1 
ATOM 3110 C CB  . LEU D 2 23  ? 284.763 285.353 418.794 1.00 78.77  ? 23  LEU H CB  1 
ATOM 3111 C CG  . LEU D 2 23  ? 284.235 285.640 420.202 1.00 78.77  ? 23  LEU H CG  1 
ATOM 3112 C CD1 . LEU D 2 23  ? 285.282 286.258 421.104 1.00 78.77  ? 23  LEU H CD1 1 
ATOM 3113 C CD2 . LEU D 2 23  ? 283.021 286.531 420.124 1.00 78.77  ? 23  LEU H CD2 1 
ATOM 3114 N N   . SER D 2 24  ? 284.435 283.434 416.561 1.00 77.61  ? 24  SER H N   1 
ATOM 3115 C CA  . SER D 2 24  ? 284.268 283.137 415.148 1.00 77.61  ? 24  SER H CA  1 
ATOM 3116 C C   . SER D 2 24  ? 282.843 283.485 414.743 1.00 77.61  ? 24  SER H C   1 
ATOM 3117 O O   . SER D 2 24  ? 282.032 283.926 415.559 1.00 77.61  ? 24  SER H O   1 
ATOM 3118 C CB  . SER D 2 24  ? 284.596 281.675 414.841 1.00 77.61  ? 24  SER H CB  1 
ATOM 3119 O OG  . SER D 2 24  ? 283.657 280.813 415.447 1.00 77.61  ? 24  SER H OG  1 
ATOM 3120 N N   . CYS D 2 25  ? 282.544 283.272 413.467 1.00 75.36  ? 25  CYS H N   1 
ATOM 3121 C CA  . CYS D 2 25  ? 281.253 283.628 412.902 1.00 75.36  ? 25  CYS H CA  1 
ATOM 3122 C C   . CYS D 2 25  ? 281.063 282.756 411.670 1.00 75.36  ? 25  CYS H C   1 
ATOM 3123 O O   . CYS D 2 25  ? 281.964 282.677 410.832 1.00 75.36  ? 25  CYS H O   1 
ATOM 3124 C CB  . CYS D 2 25  ? 281.221 285.119 412.558 1.00 75.36  ? 25  CYS H CB  1 
ATOM 3125 S SG  . CYS D 2 25  ? 279.619 285.829 412.184 1.00 75.36  ? 25  CYS H SG  1 
ATOM 3126 N N   . ALA D 2 26  ? 279.915 282.083 411.573 1.00 73.42  ? 26  ALA H N   1 
ATOM 3127 C CA  . ALA D 2 26  ? 279.754 281.041 410.559 1.00 73.42  ? 26  ALA H CA  1 
ATOM 3128 C C   . ALA D 2 26  ? 279.567 281.632 409.170 1.00 73.42  ? 26  ALA H C   1 
ATOM 3129 O O   . ALA D 2 26  ? 280.221 281.196 408.215 1.00 73.42  ? 26  ALA H O   1 
ATOM 3130 C CB  . ALA D 2 26  ? 278.583 280.132 410.914 1.00 73.42  ? 26  ALA H CB  1 
ATOM 3131 N N   . ALA D 2 27  ? 278.645 282.593 409.038 1.00 70.93  ? 27  ALA H N   1 
ATOM 3132 C CA  . ALA D 2 27  ? 278.470 283.453 407.862 1.00 70.93  ? 27  ALA H CA  1 
ATOM 3133 C C   . ALA D 2 27  ? 278.142 282.646 406.600 1.00 70.93  ? 27  ALA H C   1 
ATOM 3134 O O   . ALA D 2 27  ? 278.931 282.542 405.664 1.00 70.93  ? 27  ALA H O   1 
ATOM 3135 C CB  . ALA D 2 27  ? 279.701 284.341 407.657 1.00 70.93  ? 27  ALA H CB  1 
ATOM 3136 N N   . SER D 2 28  ? 276.952 282.060 406.614 1.00 72.09  ? 28  SER H N   1 
ATOM 3137 C CA  . SER D 2 28  ? 276.429 281.327 405.473 1.00 72.09  ? 28  SER H CA  1 
ATOM 3138 C C   . SER D 2 28  ? 275.194 282.021 404.917 1.00 72.09  ? 28  SER H C   1 
ATOM 3139 O O   . SER D 2 28  ? 274.451 282.680 405.646 1.00 72.09  ? 28  SER H O   1 
ATOM 3140 C CB  . SER D 2 28  ? 276.077 279.889 405.858 1.00 72.09  ? 28  SER H CB  1 
ATOM 3141 O OG  . SER D 2 28  ? 275.004 279.863 406.782 1.00 72.09  ? 28  SER H OG  1 
ATOM 3142 N N   . GLY D 2 29  ? 274.977 281.858 403.614 1.00 67.07  ? 29  GLY H N   1 
ATOM 3143 C CA  . GLY D 2 29  ? 273.804 282.391 402.949 1.00 67.07  ? 29  GLY H CA  1 
ATOM 3144 C C   . GLY D 2 29  ? 274.075 283.483 401.942 1.00 67.07  ? 29  GLY H C   1 
ATOM 3145 O O   . GLY D 2 29  ? 273.132 283.932 401.280 1.00 67.07  ? 29  GLY H O   1 
ATOM 3146 N N   . PHE D 2 30  ? 275.323 283.913 401.792 1.00 61.59  ? 30  PHE H N   1 
ATOM 3147 C CA  . PHE D 2 30  ? 275.682 285.002 400.896 1.00 61.59  ? 30  PHE H CA  1 
ATOM 3148 C C   . PHE D 2 30  ? 277.171 284.895 400.615 1.00 61.59  ? 30  PHE H C   1 
ATOM 3149 O O   . PHE D 2 30  ? 277.895 284.152 401.280 1.00 61.59  ? 30  PHE H O   1 
ATOM 3150 C CB  . PHE D 2 30  ? 275.312 286.369 401.489 1.00 61.59  ? 30  PHE H CB  1 
ATOM 3151 C CG  . PHE D 2 30  ? 276.044 286.711 402.757 1.00 61.59  ? 30  PHE H CG  1 
ATOM 3152 C CD1 . PHE D 2 30  ? 275.597 286.242 403.979 1.00 61.59  ? 30  PHE H CD1 1 
ATOM 3153 C CD2 . PHE D 2 30  ? 277.140 287.554 402.738 1.00 61.59  ? 30  PHE H CD2 1 
ATOM 3154 C CE1 . PHE D 2 30  ? 276.258 286.555 405.142 1.00 61.59  ? 30  PHE H CE1 1 
ATOM 3155 C CE2 . PHE D 2 30  ? 277.797 287.876 403.905 1.00 61.59  ? 30  PHE H CE2 1 
ATOM 3156 C CZ  . PHE D 2 30  ? 277.350 287.377 405.105 1.00 61.59  ? 30  PHE H CZ  1 
ATOM 3157 N N   . THR D 2 31  ? 277.619 285.641 399.613 1.00 57.66  ? 31  THR H N   1 
ATOM 3158 C CA  . THR D 2 31  ? 279.035 285.663 399.269 1.00 57.66  ? 31  THR H CA  1 
ATOM 3159 C C   . THR D 2 31  ? 279.792 286.438 400.335 1.00 57.66  ? 31  THR H C   1 
ATOM 3160 O O   . THR D 2 31  ? 279.756 287.671 400.363 1.00 57.66  ? 31  THR H O   1 
ATOM 3161 C CB  . THR D 2 31  ? 279.234 286.276 397.891 1.00 57.66  ? 31  THR H CB  1 
ATOM 3162 O OG1 . THR D 2 31  ? 278.693 287.600 397.879 1.00 57.66  ? 31  THR H OG1 1 
ATOM 3163 C CG2 . THR D 2 31  ? 278.531 285.433 396.850 1.00 57.66  ? 31  THR H CG2 1 
ATOM 3164 N N   . PHE D 2 32  ? 280.464 285.700 401.221 1.00 62.17  ? 32  PHE H N   1 
ATOM 3165 C CA  . PHE D 2 32  ? 281.140 286.282 402.375 1.00 62.17  ? 32  PHE H CA  1 
ATOM 3166 C C   . PHE D 2 32  ? 282.296 287.182 401.971 1.00 62.17  ? 32  PHE H C   1 
ATOM 3167 O O   . PHE D 2 32  ? 282.553 288.191 402.634 1.00 62.17  ? 32  PHE H O   1 
ATOM 3168 C CB  . PHE D 2 32  ? 281.634 285.162 403.286 1.00 62.17  ? 32  PHE H CB  1 
ATOM 3169 C CG  . PHE D 2 32  ? 282.445 285.634 404.447 1.00 62.17  ? 32  PHE H CG  1 
ATOM 3170 C CD1 . PHE D 2 32  ? 281.840 286.246 405.520 1.00 62.17  ? 32  PHE H CD1 1 
ATOM 3171 C CD2 . PHE D 2 32  ? 283.816 285.455 404.468 1.00 62.17  ? 32  PHE H CD2 1 
ATOM 3172 C CE1 . PHE D 2 32  ? 282.580 286.672 406.594 1.00 62.17  ? 32  PHE H CE1 1 
ATOM 3173 C CE2 . PHE D 2 32  ? 284.561 285.894 405.534 1.00 62.17  ? 32  PHE H CE2 1 
ATOM 3174 C CZ  . PHE D 2 32  ? 283.940 286.502 406.597 1.00 62.17  ? 32  PHE H CZ  1 
ATOM 3175 N N   . SER D 2 33  ? 282.986 286.854 400.885 1.00 58.32  ? 33  SER H N   1 
ATOM 3176 C CA  . SER D 2 33  ? 284.165 287.605 400.485 1.00 58.32  ? 33  SER H CA  1 
ATOM 3177 C C   . SER D 2 33  ? 283.842 288.827 399.643 1.00 58.32  ? 33  SER H C   1 
ATOM 3178 O O   . SER D 2 33  ? 284.699 289.263 398.871 1.00 58.32  ? 33  SER H O   1 
ATOM 3179 C CB  . SER D 2 33  ? 285.124 286.701 399.716 1.00 58.32  ? 33  SER H CB  1 
ATOM 3180 O OG  . SER D 2 33  ? 284.554 286.297 398.488 1.00 58.32  ? 33  SER H OG  1 
ATOM 3181 N N   . SER D 2 34  ? 282.628 289.365 399.739 1.00 54.41  ? 34  SER H N   1 
ATOM 3182 C CA  . SER D 2 34  ? 282.298 290.595 399.035 1.00 54.41  ? 34  SER H CA  1 
ATOM 3183 C C   . SER D 2 34  ? 282.024 291.728 400.012 1.00 54.41  ? 34  SER H C   1 
ATOM 3184 O O   . SER D 2 34  ? 282.332 292.888 399.727 1.00 54.41  ? 34  SER H O   1 
ATOM 3185 C CB  . SER D 2 34  ? 281.088 290.374 398.132 1.00 54.41  ? 34  SER H CB  1 
ATOM 3186 O OG  . SER D 2 34  ? 281.364 289.403 397.144 1.00 54.41  ? 34  SER H OG  1 
ATOM 3187 N N   . TYR D 2 35  ? 281.469 291.404 401.169 1.00 57.49  ? 35  TYR H N   1 
ATOM 3188 C CA  . TYR D 2 35  ? 280.984 292.373 402.135 1.00 57.49  ? 35  TYR H CA  1 
ATOM 3189 C C   . TYR D 2 35  ? 281.997 292.596 403.247 1.00 57.49  ? 35  TYR H C   1 
ATOM 3190 O O   . TYR D 2 35  ? 282.814 291.730 403.561 1.00 57.49  ? 35  TYR H O   1 
ATOM 3191 C CB  . TYR D 2 35  ? 279.666 291.891 402.730 1.00 57.49  ? 35  TYR H CB  1 
ATOM 3192 C CG  . TYR D 2 35  ? 278.545 291.819 401.732 1.00 57.49  ? 35  TYR H CG  1 
ATOM 3193 C CD1 . TYR D 2 35  ? 277.778 292.934 401.442 1.00 57.49  ? 35  TYR H CD1 1 
ATOM 3194 C CD2 . TYR D 2 35  ? 278.265 290.637 401.066 1.00 57.49  ? 35  TYR H CD2 1 
ATOM 3195 C CE1 . TYR D 2 35  ? 276.757 292.871 400.531 1.00 57.49  ? 35  TYR H CE1 1 
ATOM 3196 C CE2 . TYR D 2 35  ? 277.247 290.566 400.145 1.00 57.49  ? 35  TYR H CE2 1 
ATOM 3197 C CZ  . TYR D 2 35  ? 276.497 291.686 399.885 1.00 57.49  ? 35  TYR H CZ  1 
ATOM 3198 O OH  . TYR D 2 35  ? 275.480 291.619 398.970 1.00 57.49  ? 35  TYR H OH  1 
ATOM 3199 N N   . ALA D 2 36  ? 281.921 293.773 403.854 1.00 60.79  ? 36  ALA H N   1 
ATOM 3200 C CA  . ALA D 2 36  ? 282.701 294.049 405.043 1.00 60.79  ? 36  ALA H CA  1 
ATOM 3201 C C   . ALA D 2 36  ? 282.004 293.457 406.264 1.00 60.79  ? 36  ALA H C   1 
ATOM 3202 O O   . ALA D 2 36  ? 280.823 293.113 406.227 1.00 60.79  ? 36  ALA H O   1 
ATOM 3203 C CB  . ALA D 2 36  ? 282.908 295.550 405.205 1.00 60.79  ? 36  ALA H CB  1 
ATOM 3204 N N   . MET D 2 37  ? 282.756 293.308 407.348 1.00 65.18  ? 37  MET H N   1 
ATOM 3205 C CA  . MET D 2 37  ? 282.246 292.665 408.549 1.00 65.18  ? 37  MET H CA  1 
ATOM 3206 C C   . MET D 2 37  ? 282.556 293.502 409.775 1.00 65.18  ? 37  MET H C   1 
ATOM 3207 O O   . MET D 2 37  ? 283.334 294.454 409.726 1.00 65.18  ? 37  MET H O   1 
ATOM 3208 C CB  . MET D 2 37  ? 282.818 291.260 408.723 1.00 65.18  ? 37  MET H CB  1 
ATOM 3209 C CG  . MET D 2 37  ? 282.283 290.283 407.725 1.00 65.18  ? 37  MET H CG  1 
ATOM 3210 S SD  . MET D 2 37  ? 280.511 290.162 407.942 1.00 65.18  ? 37  MET H SD  1 
ATOM 3211 C CE  . MET D 2 37  ? 280.078 289.250 406.481 1.00 65.18  ? 37  MET H CE  1 
ATOM 3212 N N   . SER D 2 38  ? 281.937 293.127 410.891 1.00 69.79  ? 38  SER H N   1 
ATOM 3213 C CA  . SER D 2 38  ? 282.017 293.927 412.102 1.00 69.79  ? 38  SER H CA  1 
ATOM 3214 C C   . SER D 2 38  ? 281.790 293.054 413.323 1.00 69.79  ? 38  SER H C   1 
ATOM 3215 O O   . SER D 2 38  ? 281.131 292.016 413.246 1.00 69.79  ? 38  SER H O   1 
ATOM 3216 C CB  . SER D 2 38  ? 280.979 295.044 412.101 1.00 69.79  ? 38  SER H CB  1 
ATOM 3217 O OG  . SER D 2 38  ? 281.183 295.954 411.048 1.00 69.79  ? 38  SER H OG  1 
ATOM 3218 N N   . TRP D 2 39  ? 282.329 293.501 414.452 1.00 73.55  ? 39  TRP H N   1 
ATOM 3219 C CA  . TRP D 2 39  ? 281.940 293.012 415.766 1.00 73.55  ? 39  TRP H CA  1 
ATOM 3220 C C   . TRP D 2 39  ? 281.257 294.135 416.529 1.00 73.55  ? 39  TRP H C   1 
ATOM 3221 O O   . TRP D 2 39  ? 281.791 295.242 416.620 1.00 73.55  ? 39  TRP H O   1 
ATOM 3222 C CB  . TRP D 2 39  ? 283.137 292.501 416.562 1.00 73.55  ? 39  TRP H CB  1 
ATOM 3223 C CG  . TRP D 2 39  ? 283.664 291.210 416.075 1.00 73.55  ? 39  TRP H CG  1 
ATOM 3224 C CD1 . TRP D 2 39  ? 284.762 291.014 415.311 1.00 73.55  ? 39  TRP H CD1 1 
ATOM 3225 C CD2 . TRP D 2 39  ? 283.104 289.917 416.313 1.00 73.55  ? 39  TRP H CD2 1 
ATOM 3226 N NE1 . TRP D 2 39  ? 284.934 289.680 415.059 1.00 73.55  ? 39  TRP H NE1 1 
ATOM 3227 C CE2 . TRP D 2 39  ? 283.924 288.984 415.666 1.00 73.55  ? 39  TRP H CE2 1 
ATOM 3228 C CE3 . TRP D 2 39  ? 281.989 289.460 417.018 1.00 73.55  ? 39  TRP H CE3 1 
ATOM 3229 C CZ2 . TRP D 2 39  ? 283.667 287.623 415.696 1.00 73.55  ? 39  TRP H CZ2 1 
ATOM 3230 C CZ3 . TRP D 2 39  ? 281.735 288.106 417.047 1.00 73.55  ? 39  TRP H CZ3 1 
ATOM 3231 C CH2 . TRP D 2 39  ? 282.568 287.205 416.389 1.00 73.55  ? 39  TRP H CH2 1 
ATOM 3232 N N   . VAL D 2 40  ? 280.074 293.853 417.062 1.00 79.06  ? 40  VAL H N   1 
ATOM 3233 C CA  . VAL D 2 40  ? 279.312 294.805 417.858 1.00 79.06  ? 40  VAL H CA  1 
ATOM 3234 C C   . VAL D 2 40  ? 278.994 294.147 419.192 1.00 79.06  ? 40  VAL H C   1 
ATOM 3235 O O   . VAL D 2 40  ? 278.496 293.017 419.229 1.00 79.06  ? 40  VAL H O   1 
ATOM 3236 C CB  . VAL D 2 40  ? 278.026 295.252 417.137 1.00 79.06  ? 40  VAL H CB  1 
ATOM 3237 C CG1 . VAL D 2 40  ? 277.192 296.153 418.024 1.00 79.06  ? 40  VAL H CG1 1 
ATOM 3238 C CG2 . VAL D 2 40  ? 278.365 295.958 415.846 1.00 79.06  ? 40  VAL H CG2 1 
ATOM 3239 N N   . ARG D 2 41  ? 279.288 294.849 420.278 1.00 85.95  ? 41  ARG H N   1 
ATOM 3240 C CA  . ARG D 2 41  ? 279.136 294.336 421.627 1.00 85.95  ? 41  ARG H CA  1 
ATOM 3241 C C   . ARG D 2 41  ? 277.933 294.955 422.319 1.00 85.95  ? 41  ARG H C   1 
ATOM 3242 O O   . ARG D 2 41  ? 277.482 296.045 421.961 1.00 85.95  ? 41  ARG H O   1 
ATOM 3243 C CB  . ARG D 2 41  ? 280.392 294.621 422.436 1.00 85.95  ? 41  ARG H CB  1 
ATOM 3244 C CG  . ARG D 2 41  ? 280.778 296.059 422.441 1.00 85.95  ? 41  ARG H CG  1 
ATOM 3245 C CD  . ARG D 2 41  ? 282.030 296.293 423.241 1.00 85.95  ? 41  ARG H CD  1 
ATOM 3246 N NE  . ARG D 2 41  ? 281.774 296.205 424.665 1.00 85.95  ? 41  ARG H NE  1 
ATOM 3247 C CZ  . ARG D 2 41  ? 282.724 296.087 425.578 1.00 85.95  ? 41  ARG H CZ  1 
ATOM 3248 N NH1 . ARG D 2 41  ? 283.995 296.031 425.206 1.00 85.95  ? 41  ARG H NH1 1 
ATOM 3249 N NH2 . ARG D 2 41  ? 282.399 296.029 426.860 1.00 85.95  ? 41  ARG H NH2 1 
ATOM 3250 N N   . GLN D 2 42  ? 277.417 294.248 423.322 1.00 89.70  ? 42  GLN H N   1 
ATOM 3251 C CA  . GLN D 2 42  ? 276.307 294.731 424.135 1.00 89.70  ? 42  GLN H CA  1 
ATOM 3252 C C   . GLN D 2 42  ? 276.588 294.403 425.593 1.00 89.70  ? 42  GLN H C   1 
ATOM 3253 O O   . GLN D 2 42  ? 276.575 293.231 425.980 1.00 89.70  ? 42  GLN H O   1 
ATOM 3254 C CB  . GLN D 2 42  ? 274.983 294.120 423.694 1.00 89.70  ? 42  GLN H CB  1 
ATOM 3255 C CG  . GLN D 2 42  ? 273.796 294.689 424.433 1.00 89.70  ? 42  GLN H CG  1 
ATOM 3256 C CD  . GLN D 2 42  ? 272.481 294.151 423.930 1.00 89.70  ? 42  GLN H CD  1 
ATOM 3257 O OE1 . GLN D 2 42  ? 272.442 293.284 423.058 1.00 89.70  ? 42  GLN H OE1 1 
ATOM 3258 N NE2 . GLN D 2 42  ? 271.390 294.665 424.477 1.00 89.70  ? 42  GLN H NE2 1 
ATOM 3259 N N   . THR D 2 43  ? 276.814 295.446 426.396 1.00 93.69  ? 43  THR H N   1 
ATOM 3260 C CA  . THR D 2 43  ? 277.109 295.314 427.814 1.00 93.69  ? 43  THR H CA  1 
ATOM 3261 C C   . THR D 2 43  ? 275.913 294.721 428.567 1.00 93.69  ? 43  THR H C   1 
ATOM 3262 O O   . THR D 2 43  ? 274.781 294.774 428.082 1.00 93.69  ? 43  THR H O   1 
ATOM 3263 C CB  . THR D 2 43  ? 277.458 296.688 428.384 1.00 93.69  ? 43  THR H CB  1 
ATOM 3264 O OG1 . THR D 2 43  ? 276.324 297.550 428.255 1.00 93.69  ? 43  THR H OG1 1 
ATOM 3265 C CG2 . THR D 2 43  ? 278.637 297.287 427.643 1.00 93.69  ? 43  THR H CG2 1 
ATOM 3266 N N   . PRO D 2 44  ? 276.133 294.154 429.765 1.00 95.77  ? 44  PRO H N   1 
ATOM 3267 C CA  . PRO D 2 44  ? 274.983 293.737 430.587 1.00 95.77  ? 44  PRO H CA  1 
ATOM 3268 C C   . PRO D 2 44  ? 274.165 294.894 431.136 1.00 95.77  ? 44  PRO H C   1 
ATOM 3269 O O   . PRO D 2 44  ? 273.068 294.660 431.657 1.00 95.77  ? 44  PRO H O   1 
ATOM 3270 C CB  . PRO D 2 44  ? 275.630 292.926 431.717 1.00 95.77  ? 44  PRO H CB  1 
ATOM 3271 C CG  . PRO D 2 44  ? 277.028 293.397 431.773 1.00 95.77  ? 44  PRO H CG  1 
ATOM 3272 C CD  . PRO D 2 44  ? 277.404 293.695 430.358 1.00 95.77  ? 44  PRO H CD  1 
ATOM 3273 N N   . GLU D 2 45  ? 274.654 296.129 431.027 1.00 96.48  ? 45  GLU H N   1 
ATOM 3274 C CA  . GLU D 2 45  ? 273.888 297.331 431.320 1.00 96.48  ? 45  GLU H CA  1 
ATOM 3275 C C   . GLU D 2 45  ? 272.975 297.743 430.172 1.00 96.48  ? 45  GLU H C   1 
ATOM 3276 O O   . GLU D 2 45  ? 272.370 298.819 430.251 1.00 96.48  ? 45  GLU H O   1 
ATOM 3277 C CB  . GLU D 2 45  ? 274.849 298.472 431.647 1.00 96.48  ? 45  GLU H CB  1 
ATOM 3278 C CG  . GLU D 2 45  ? 275.700 298.209 432.872 1.00 96.48  ? 45  GLU H CG  1 
ATOM 3279 C CD  . GLU D 2 45  ? 276.722 299.296 433.111 1.00 96.48  ? 45  GLU H CD  1 
ATOM 3280 O OE1 . GLU D 2 45  ? 276.835 300.201 432.258 1.00 96.48  ? 45  GLU H OE1 1 
ATOM 3281 O OE2 . GLU D 2 45  ? 277.420 299.239 434.145 1.00 96.48  ? 45  GLU H OE2 1 
ATOM 3282 N N   . LYS D 2 46  ? 272.899 296.923 429.115 1.00 96.10  ? 46  LYS H N   1 
ATOM 3283 C CA  . LYS D 2 46  ? 272.013 297.101 427.958 1.00 96.10  ? 46  LYS H CA  1 
ATOM 3284 C C   . LYS D 2 46  ? 272.299 298.401 427.206 1.00 96.10  ? 46  LYS H C   1 
ATOM 3285 O O   . LYS D 2 46  ? 271.418 299.239 427.011 1.00 96.10  ? 46  LYS H O   1 
ATOM 3286 C CB  . LYS D 2 46  ? 270.536 297.012 428.354 1.00 96.10  ? 46  LYS H CB  1 
ATOM 3287 C CG  . LYS D 2 46  ? 270.094 295.648 428.845 1.00 96.10  ? 46  LYS H CG  1 
ATOM 3288 C CD  . LYS D 2 46  ? 268.607 295.658 429.160 1.00 96.10  ? 46  LYS H CD  1 
ATOM 3289 C CE  . LYS D 2 46  ? 268.106 294.290 429.593 1.00 96.10  ? 46  LYS H CE  1 
ATOM 3290 N NZ  . LYS D 2 46  ? 268.654 293.895 430.917 1.00 96.10  ? 46  LYS H NZ  1 
ATOM 3291 N N   . ARG D 2 47  ? 273.548 298.566 426.784 1.00 92.70  ? 47  ARG H N   1 
ATOM 3292 C CA  . ARG D 2 47  ? 273.901 299.577 425.800 1.00 92.70  ? 47  ARG H CA  1 
ATOM 3293 C C   . ARG D 2 47  ? 274.798 298.942 424.748 1.00 92.70  ? 47  ARG H C   1 
ATOM 3294 O O   . ARG D 2 47  ? 275.634 298.088 425.059 1.00 92.70  ? 47  ARG H O   1 
ATOM 3295 C CB  . ARG D 2 47  ? 274.581 300.807 426.435 1.00 92.70  ? 47  ARG H CB  1 
ATOM 3296 C CG  . ARG D 2 47  ? 275.938 300.587 427.080 1.00 92.70  ? 47  ARG H CG  1 
ATOM 3297 C CD  . ARG D 2 47  ? 276.483 301.889 427.630 1.00 92.70  ? 47  ARG H CD  1 
ATOM 3298 N NE  . ARG D 2 47  ? 276.774 302.837 426.560 1.00 92.70  ? 47  ARG H NE  1 
ATOM 3299 C CZ  . ARG D 2 47  ? 276.931 304.145 426.738 1.00 92.70  ? 47  ARG H CZ  1 
ATOM 3300 N NH1 . ARG D 2 47  ? 277.191 304.931 425.702 1.00 92.70  ? 47  ARG H NH1 1 
ATOM 3301 N NH2 . ARG D 2 47  ? 276.818 304.672 427.949 1.00 92.70  ? 47  ARG H NH2 1 
ATOM 3302 N N   . LEU D 2 48  ? 274.593 299.335 423.497 1.00 88.13  ? 48  LEU H N   1 
ATOM 3303 C CA  . LEU D 2 48  ? 275.324 298.757 422.382 1.00 88.13  ? 48  LEU H CA  1 
ATOM 3304 C C   . LEU D 2 48  ? 276.559 299.596 422.090 1.00 88.13  ? 48  LEU H C   1 
ATOM 3305 O O   . LEU D 2 48  ? 276.506 300.828 422.116 1.00 88.13  ? 48  LEU H O   1 
ATOM 3306 C CB  . LEU D 2 48  ? 274.431 298.681 421.146 1.00 88.13  ? 48  LEU H CB  1 
ATOM 3307 C CG  . LEU D 2 48  ? 273.201 297.783 421.114 1.00 88.13  ? 48  LEU H CG  1 
ATOM 3308 C CD1 . LEU D 2 48  ? 272.358 298.099 419.897 1.00 88.13  ? 48  LEU H CD1 1 
ATOM 3309 C CD2 . LEU D 2 48  ? 273.627 296.347 421.071 1.00 88.13  ? 48  LEU H CD2 1 
ATOM 3310 N N   . GLU D 2 49  ? 277.675 298.923 421.829 1.00 86.03  ? 49  GLU H N   1 
ATOM 3311 C CA  . GLU D 2 49  ? 278.929 299.591 421.512 1.00 86.03  ? 49  GLU H CA  1 
ATOM 3312 C C   . GLU D 2 49  ? 279.579 298.898 420.326 1.00 86.03  ? 49  GLU H C   1 
ATOM 3313 O O   . GLU D 2 49  ? 279.274 297.746 420.018 1.00 86.03  ? 49  GLU H O   1 
ATOM 3314 C CB  . GLU D 2 49  ? 279.895 299.586 422.700 1.00 86.03  ? 49  GLU H CB  1 
ATOM 3315 C CG  . GLU D 2 49  ? 279.460 300.410 423.890 1.00 86.03  ? 49  GLU H CG  1 
ATOM 3316 C CD  . GLU D 2 49  ? 280.431 300.304 425.046 1.00 86.03  ? 49  GLU H CD  1 
ATOM 3317 O OE1 . GLU D 2 49  ? 281.357 299.471 424.970 1.00 86.03  ? 49  GLU H OE1 1 
ATOM 3318 O OE2 . GLU D 2 49  ? 280.273 301.058 426.029 1.00 86.03  ? 49  GLU H OE2 1 
ATOM 3319 N N   . TRP D 2 50  ? 280.485 299.609 419.670 1.00 76.86  ? 50  TRP H N   1 
ATOM 3320 C CA  . TRP D 2 50  ? 281.158 299.120 418.477 1.00 76.86  ? 50  TRP H CA  1 
ATOM 3321 C C   . TRP D 2 50  ? 282.569 298.662 418.819 1.00 76.86  ? 50  TRP H C   1 
ATOM 3322 O O   . TRP D 2 50  ? 283.237 299.264 419.663 1.00 76.86  ? 50  TRP H O   1 
ATOM 3323 C CB  . TRP D 2 50  ? 281.198 300.216 417.417 1.00 76.86  ? 50  TRP H CB  1 
ATOM 3324 C CG  . TRP D 2 50  ? 281.952 299.855 416.199 1.00 76.86  ? 50  TRP H CG  1 
ATOM 3325 C CD1 . TRP D 2 50  ? 281.622 298.915 415.277 1.00 76.86  ? 50  TRP H CD1 1 
ATOM 3326 C CD2 . TRP D 2 50  ? 283.186 300.427 415.772 1.00 76.86  ? 50  TRP H CD2 1 
ATOM 3327 N NE1 . TRP D 2 50  ? 282.574 298.870 414.294 1.00 76.86  ? 50  TRP H NE1 1 
ATOM 3328 C CE2 . TRP D 2 50  ? 283.547 299.791 414.576 1.00 76.86  ? 50  TRP H CE2 1 
ATOM 3329 C CE3 . TRP D 2 50  ? 284.022 301.418 416.287 1.00 76.86  ? 50  TRP H CE3 1 
ATOM 3330 C CZ2 . TRP D 2 50  ? 284.706 300.115 413.888 1.00 76.86  ? 50  TRP H CZ2 1 
ATOM 3331 C CZ3 . TRP D 2 50  ? 285.165 301.740 415.602 1.00 76.86  ? 50  TRP H CZ3 1 
ATOM 3332 C CH2 . TRP D 2 50  ? 285.499 301.091 414.416 1.00 76.86  ? 50  TRP H CH2 1 
ATOM 3333 N N   . VAL D 2 51  ? 283.020 297.590 418.168 1.00 76.75  ? 51  VAL H N   1 
ATOM 3334 C CA  . VAL D 2 51  ? 284.346 297.046 418.440 1.00 76.75  ? 51  VAL H CA  1 
ATOM 3335 C C   . VAL D 2 51  ? 285.291 297.302 417.275 1.00 76.75  ? 51  VAL H C   1 
ATOM 3336 O O   . VAL D 2 51  ? 286.283 298.025 417.421 1.00 76.75  ? 51  VAL H O   1 
ATOM 3337 C CB  . VAL D 2 51  ? 284.278 295.542 418.749 1.00 76.75  ? 51  VAL H CB  1 
ATOM 3338 C CG1 . VAL D 2 51  ? 285.666 294.984 418.962 1.00 76.75  ? 51  VAL H CG1 1 
ATOM 3339 C CG2 . VAL D 2 51  ? 283.427 295.297 419.956 1.00 76.75  ? 51  VAL H CG2 1 
ATOM 3340 N N   . ALA D 2 52  ? 284.990 296.731 416.110 1.00 73.13  ? 52  ALA H N   1 
ATOM 3341 C CA  . ALA D 2 52  ? 285.931 296.760 414.998 1.00 73.13  ? 52  ALA H CA  1 
ATOM 3342 C C   . ALA D 2 52  ? 285.205 296.475 413.693 1.00 73.13  ? 52  ALA H C   1 
ATOM 3343 O O   . ALA D 2 52  ? 284.169 295.813 413.674 1.00 73.13  ? 52  ALA H O   1 
ATOM 3344 C CB  . ALA D 2 52  ? 287.059 295.743 415.198 1.00 73.13  ? 52  ALA H CB  1 
ATOM 3345 N N   . THR D 2 53  ? 285.774 296.983 412.598 1.00 69.54  ? 53  THR H N   1 
ATOM 3346 C CA  . THR D 2 53  ? 285.366 296.623 411.246 1.00 69.54  ? 53  THR H CA  1 
ATOM 3347 C C   . THR D 2 53  ? 286.570 296.116 410.470 1.00 69.54  ? 53  THR H C   1 
ATOM 3348 O O   . THR D 2 53  ? 287.702 296.545 410.698 1.00 69.54  ? 53  THR H O   1 
ATOM 3349 C CB  . THR D 2 53  ? 284.761 297.793 410.462 1.00 69.54  ? 53  THR H CB  1 
ATOM 3350 O OG1 . THR D 2 53  ? 285.698 298.873 410.408 1.00 69.54  ? 53  THR H OG1 1 
ATOM 3351 C CG2 . THR D 2 53  ? 283.481 298.270 411.081 1.00 69.54  ? 53  THR H CG2 1 
ATOM 3352 N N   . ILE D 2 54  ? 286.311 295.206 409.540 1.00 64.32  ? 54  ILE H N   1 
ATOM 3353 C CA  . ILE D 2 54  ? 287.316 294.736 408.600 1.00 64.32  ? 54  ILE H CA  1 
ATOM 3354 C C   . ILE D 2 54  ? 286.699 294.786 407.208 1.00 64.32  ? 54  ILE H C   1 
ATOM 3355 O O   . ILE D 2 54  ? 285.505 294.526 407.027 1.00 64.32  ? 54  ILE H O   1 
ATOM 3356 C CB  . ILE D 2 54  ? 287.843 293.321 408.974 1.00 64.32  ? 54  ILE H CB  1 
ATOM 3357 C CG1 . ILE D 2 54  ? 289.006 292.906 408.073 1.00 64.32  ? 54  ILE H CG1 1 
ATOM 3358 C CG2 . ILE D 2 54  ? 286.735 292.282 408.999 1.00 64.32  ? 54  ILE H CG2 1 
ATOM 3359 C CD1 . ILE D 2 54  ? 289.739 291.695 408.543 1.00 64.32  ? 54  ILE H CD1 1 
ATOM 3360 N N   . SER D 2 55  ? 287.508 295.162 406.224 1.00 62.83  ? 55  SER H N   1 
ATOM 3361 C CA  . SER D 2 55  ? 287.016 295.466 404.888 1.00 62.83  ? 55  SER H CA  1 
ATOM 3362 C C   . SER D 2 55  ? 286.764 294.187 404.093 1.00 62.83  ? 55  SER H C   1 
ATOM 3363 O O   . SER D 2 55  ? 286.606 293.094 404.642 1.00 62.83  ? 55  SER H O   1 
ATOM 3364 C CB  . SER D 2 55  ? 287.994 296.373 404.156 1.00 62.83  ? 55  SER H CB  1 
ATOM 3365 O OG  . SER D 2 55  ? 289.192 295.680 403.866 1.00 62.83  ? 55  SER H OG  1 
ATOM 3366 N N   . ASP D 2 56  ? 286.662 294.349 402.771 1.00 61.26  ? 56  ASP H N   1 
ATOM 3367 C CA  . ASP D 2 56  ? 286.451 293.228 401.859 1.00 61.26  ? 56  ASP H CA  1 
ATOM 3368 C C   . ASP D 2 56  ? 287.573 292.202 401.923 1.00 61.26  ? 56  ASP H C   1 
ATOM 3369 O O   . ASP D 2 56  ? 287.364 291.070 402.372 1.00 61.26  ? 56  ASP H O   1 
ATOM 3370 C CB  . ASP D 2 56  ? 286.337 293.759 400.438 1.00 61.26  ? 56  ASP H CB  1 
ATOM 3371 C CG  . ASP D 2 56  ? 286.279 292.660 399.426 1.00 61.26  ? 56  ASP H CG  1 
ATOM 3372 O OD1 . ASP D 2 56  ? 285.215 292.037 399.308 1.00 61.26  ? 56  ASP H OD1 1 
ATOM 3373 O OD2 . ASP D 2 56  ? 287.302 292.408 398.756 1.00 61.26  ? 56  ASP H OD2 1 
ATOM 3374 N N   . GLY D 2 57  ? 288.769 292.577 401.483 1.00 62.47  ? 57  GLY H N   1 
ATOM 3375 C CA  . GLY D 2 57  ? 289.885 291.657 401.467 1.00 62.47  ? 57  GLY H CA  1 
ATOM 3376 C C   . GLY D 2 57  ? 290.689 291.615 402.735 1.00 62.47  ? 57  GLY H C   1 
ATOM 3377 O O   . GLY D 2 57  ? 291.722 290.944 402.784 1.00 62.47  ? 57  GLY H O   1 
ATOM 3378 N N   . GLY D 2 58  ? 290.245 292.314 403.770 1.00 63.59  ? 58  GLY H N   1 
ATOM 3379 C CA  . GLY D 2 58  ? 290.995 292.397 404.999 1.00 63.59  ? 58  GLY H CA  1 
ATOM 3380 C C   . GLY D 2 58  ? 292.062 293.459 405.014 1.00 63.59  ? 58  GLY H C   1 
ATOM 3381 O O   . GLY D 2 58  ? 293.005 293.355 405.805 1.00 63.59  ? 58  GLY H O   1 
ATOM 3382 N N   . ARG D 2 59  ? 291.942 294.443 404.146 1.00 62.18  ? 59  ARG H N   1 
ATOM 3383 C CA  . ARG D 2 59  ? 292.957 295.466 404.040 1.00 62.18  ? 59  ARG H CA  1 
ATOM 3384 C C   . ARG D 2 59  ? 292.813 296.668 404.969 1.00 62.18  ? 59  ARG H C   1 
ATOM 3385 O O   . ARG D 2 59  ? 293.756 297.045 405.639 1.00 62.18  ? 59  ARG H O   1 
ATOM 3386 C CB  . ARG D 2 59  ? 293.031 295.930 402.593 1.00 62.18  ? 59  ARG H CB  1 
ATOM 3387 C CG  . ARG D 2 59  ? 293.834 297.186 402.405 1.00 62.18  ? 59  ARG H CG  1 
ATOM 3388 C CD  . ARG D 2 59  ? 295.236 296.979 402.911 1.00 62.18  ? 59  ARG H CD  1 
ATOM 3389 N NE  . ARG D 2 59  ? 295.857 298.243 403.271 1.00 62.18  ? 59  ARG H NE  1 
ATOM 3390 C CZ  . ARG D 2 59  ? 297.074 298.344 403.780 1.00 62.18  ? 59  ARG H CZ  1 
ATOM 3391 N NH1 . ARG D 2 59  ? 297.792 297.253 403.984 1.00 62.18  ? 59  ARG H NH1 1 
ATOM 3392 N NH2 . ARG D 2 59  ? 297.576 299.528 404.080 1.00 62.18  ? 59  ARG H NH2 1 
ATOM 3393 N N   . TYR D 2 60  ? 291.632 297.257 405.011 1.00 64.41  ? 60  TYR H N   1 
ATOM 3394 C CA  . TYR D 2 60  ? 291.356 298.447 405.801 1.00 64.41  ? 60  TYR H CA  1 
ATOM 3395 C C   . TYR D 2 60  ? 290.596 298.052 407.056 1.00 64.41  ? 60  TYR H C   1 
ATOM 3396 O O   . TYR D 2 60  ? 289.524 297.449 406.971 1.00 64.41  ? 60  TYR H O   1 
ATOM 3397 C CB  . TYR D 2 60  ? 290.560 299.462 404.985 1.00 64.41  ? 60  TYR H CB  1 
ATOM 3398 C CG  . TYR D 2 60  ? 291.305 299.932 403.762 1.00 64.41  ? 60  TYR H CG  1 
ATOM 3399 C CD1 . TYR D 2 60  ? 292.294 300.898 403.855 1.00 64.41  ? 60  TYR H CD1 1 
ATOM 3400 C CD2 . TYR D 2 60  ? 291.022 299.401 402.514 1.00 64.41  ? 60  TYR H CD2 1 
ATOM 3401 C CE1 . TYR D 2 60  ? 292.981 301.323 402.735 1.00 64.41  ? 60  TYR H CE1 1 
ATOM 3402 C CE2 . TYR D 2 60  ? 291.700 299.818 401.391 1.00 64.41  ? 60  TYR H CE2 1 
ATOM 3403 C CZ  . TYR D 2 60  ? 292.677 300.780 401.507 1.00 64.41  ? 60  TYR H CZ  1 
ATOM 3404 O OH  . TYR D 2 60  ? 293.352 301.194 400.384 1.00 64.41  ? 60  TYR H OH  1 
ATOM 3405 N N   . ILE D 2 61  ? 291.161 298.385 408.213 1.00 68.39  ? 61  ILE H N   1 
ATOM 3406 C CA  . ILE D 2 61  ? 290.678 297.915 409.505 1.00 68.39  ? 61  ILE H CA  1 
ATOM 3407 C C   . ILE D 2 61  ? 290.501 299.118 410.420 1.00 68.39  ? 61  ILE H C   1 
ATOM 3408 O O   . ILE D 2 61  ? 291.418 299.930 410.561 1.00 68.39  ? 61  ILE H O   1 
ATOM 3409 C CB  . ILE D 2 61  ? 291.659 296.902 410.129 1.00 68.39  ? 61  ILE H CB  1 
ATOM 3410 C CG1 . ILE D 2 61  ? 291.774 295.648 409.265 1.00 68.39  ? 61  ILE H CG1 1 
ATOM 3411 C CG2 . ILE D 2 61  ? 291.223 296.523 411.508 1.00 68.39  ? 61  ILE H CG2 1 
ATOM 3412 C CD1 . ILE D 2 61  ? 292.903 294.741 409.665 1.00 68.39  ? 61  ILE H CD1 1 
ATOM 3413 N N   . TYR D 2 62  ? 289.328 299.236 411.038 1.00 71.34  ? 62  TYR H N   1 
ATOM 3414 C CA  . TYR D 2 62  ? 289.037 300.322 411.962 1.00 71.34  ? 62  TYR H CA  1 
ATOM 3415 C C   . TYR D 2 62  ? 288.672 299.746 413.319 1.00 71.34  ? 62  TYR H C   1 
ATOM 3416 O O   . TYR D 2 62  ? 287.749 298.939 413.416 1.00 71.34  ? 62  TYR H O   1 
ATOM 3417 C CB  . TYR D 2 62  ? 287.888 301.186 411.446 1.00 71.34  ? 62  TYR H CB  1 
ATOM 3418 C CG  . TYR D 2 62  ? 288.193 301.876 410.147 1.00 71.34  ? 62  TYR H CG  1 
ATOM 3419 C CD1 . TYR D 2 62  ? 288.975 303.021 410.115 1.00 71.34  ? 62  TYR H CD1 1 
ATOM 3420 C CD2 . TYR D 2 62  ? 287.701 301.382 408.951 1.00 71.34  ? 62  TYR H CD2 1 
ATOM 3421 C CE1 . TYR D 2 62  ? 289.258 303.654 408.925 1.00 71.34  ? 62  TYR H CE1 1 
ATOM 3422 C CE2 . TYR D 2 62  ? 287.979 302.008 407.755 1.00 71.34  ? 62  TYR H CE2 1 
ATOM 3423 C CZ  . TYR D 2 62  ? 288.760 303.141 407.747 1.00 71.34  ? 62  TYR H CZ  1 
ATOM 3424 O OH  . TYR D 2 62  ? 289.037 303.766 406.555 1.00 71.34  ? 62  TYR H OH  1 
ATOM 3425 N N   . TYR D 2 63  ? 289.378 300.175 414.361 1.00 76.82  ? 63  TYR H N   1 
ATOM 3426 C CA  . TYR D 2 63  ? 289.079 299.788 415.731 1.00 76.82  ? 63  TYR H CA  1 
ATOM 3427 C C   . TYR D 2 63  ? 288.475 300.965 416.485 1.00 76.82  ? 63  TYR H C   1 
ATOM 3428 O O   . TYR D 2 63  ? 288.525 302.110 416.032 1.00 76.82  ? 63  TYR H O   1 
ATOM 3429 C CB  . TYR D 2 63  ? 290.333 299.319 416.473 1.00 76.82  ? 63  TYR H CB  1 
ATOM 3430 C CG  . TYR D 2 63  ? 290.990 298.084 415.917 1.00 76.82  ? 63  TYR H CG  1 
ATOM 3431 C CD1 . TYR D 2 63  ? 290.456 296.827 416.149 1.00 76.82  ? 63  TYR H CD1 1 
ATOM 3432 C CD2 . TYR D 2 63  ? 292.169 298.174 415.197 1.00 76.82  ? 63  TYR H CD2 1 
ATOM 3433 C CE1 . TYR D 2 63  ? 291.066 295.694 415.654 1.00 76.82  ? 63  TYR H CE1 1 
ATOM 3434 C CE2 . TYR D 2 63  ? 292.787 297.049 414.699 1.00 76.82  ? 63  TYR H CE2 1 
ATOM 3435 C CZ  . TYR D 2 63  ? 292.229 295.813 414.926 1.00 76.82  ? 63  TYR H CZ  1 
ATOM 3436 O OH  . TYR D 2 63  ? 292.847 294.694 414.428 1.00 76.82  ? 63  TYR H OH  1 
ATOM 3437 N N   . SER D 2 64  ? 287.906 300.673 417.651 1.00 83.20  ? 64  SER H N   1 
ATOM 3438 C CA  . SER D 2 64  ? 287.468 301.726 418.551 1.00 83.20  ? 64  SER H CA  1 
ATOM 3439 C C   . SER D 2 64  ? 288.601 302.075 419.511 1.00 83.20  ? 64  SER H C   1 
ATOM 3440 O O   . SER D 2 64  ? 289.711 301.548 419.415 1.00 83.20  ? 64  SER H O   1 
ATOM 3441 C CB  . SER D 2 64  ? 286.211 301.305 419.305 1.00 83.20  ? 64  SER H CB  1 
ATOM 3442 O OG  . SER D 2 64  ? 286.489 300.263 420.215 1.00 83.20  ? 64  SER H OG  1 
ATOM 3443 N N   . ASP D 2 65  ? 288.325 302.974 420.457 1.00 87.45  ? 65  ASP H N   1 
ATOM 3444 C CA  . ASP D 2 65  ? 289.384 303.435 421.353 1.00 87.45  ? 65  ASP H CA  1 
ATOM 3445 C C   . ASP D 2 65  ? 289.695 302.410 422.437 1.00 87.45  ? 65  ASP H C   1 
ATOM 3446 O O   . ASP D 2 65  ? 290.865 302.180 422.761 1.00 87.45  ? 65  ASP H O   1 
ATOM 3447 C CB  . ASP D 2 65  ? 289.005 304.776 421.974 1.00 87.45  ? 65  ASP H CB  1 
ATOM 3448 C CG  . ASP D 2 65  ? 289.102 305.916 420.988 1.00 87.45  ? 65  ASP H CG  1 
ATOM 3449 O OD1 . ASP D 2 65  ? 289.934 305.822 420.063 1.00 87.45  ? 65  ASP H OD1 1 
ATOM 3450 O OD2 . ASP D 2 65  ? 288.355 306.904 421.135 1.00 87.45  ? 65  ASP H OD2 1 
ATOM 3451 N N   . ASN D 2 66  ? 288.668 301.776 422.999 1.00 87.67  ? 66  ASN H N   1 
ATOM 3452 C CA  . ASN D 2 66  ? 288.862 300.827 424.088 1.00 87.67  ? 66  ASN H CA  1 
ATOM 3453 C C   . ASN D 2 66  ? 289.195 299.423 423.607 1.00 87.67  ? 66  ASN H C   1 
ATOM 3454 O O   . ASN D 2 66  ? 289.143 298.483 424.404 1.00 87.67  ? 66  ASN H O   1 
ATOM 3455 C CB  . ASN D 2 66  ? 287.606 300.780 424.957 1.00 87.67  ? 66  ASN H CB  1 
ATOM 3456 C CG  . ASN D 2 66  ? 287.363 302.079 425.688 1.00 87.67  ? 66  ASN H CG  1 
ATOM 3457 O OD1 . ASN D 2 66  ? 288.292 302.700 426.200 1.00 87.67  ? 66  ASN H OD1 1 
ATOM 3458 N ND2 . ASN D 2 66  ? 286.107 302.504 425.734 1.00 87.67  ? 66  ASN H ND2 1 
ATOM 3459 N N   . VAL D 2 67  ? 289.518 299.259 422.329 1.00 85.69  ? 67  VAL H N   1 
ATOM 3460 C CA  . VAL D 2 67  ? 289.751 297.960 421.713 1.00 85.69  ? 67  VAL H CA  1 
ATOM 3461 C C   . VAL D 2 67  ? 291.144 297.928 421.093 1.00 85.69  ? 67  VAL H C   1 
ATOM 3462 O O   . VAL D 2 67  ? 291.811 296.885 421.093 1.00 85.69  ? 67  VAL H O   1 
ATOM 3463 C CB  . VAL D 2 67  ? 288.625 297.686 420.693 1.00 85.69  ? 67  VAL H CB  1 
ATOM 3464 C CG1 . VAL D 2 67  ? 288.966 296.600 419.700 1.00 85.69  ? 67  VAL H CG1 1 
ATOM 3465 C CG2 . VAL D 2 67  ? 287.357 297.295 421.433 1.00 85.69  ? 67  VAL H CG2 1 
ATOM 3466 N N   . GLU D 2 68  ? 291.629 299.106 420.677 1.00 87.64  ? 68  GLU H N   1 
ATOM 3467 C CA  . GLU D 2 68  ? 292.715 299.219 419.702 1.00 87.64  ? 68  GLU H CA  1 
ATOM 3468 C C   . GLU D 2 68  ? 294.041 298.678 420.220 1.00 87.64  ? 68  GLU H C   1 
ATOM 3469 O O   . GLU D 2 68  ? 294.806 298.082 419.453 1.00 87.64  ? 68  GLU H O   1 
ATOM 3470 C CB  . GLU D 2 68  ? 292.869 300.681 419.286 1.00 87.64  ? 68  GLU H CB  1 
ATOM 3471 C CG  . GLU D 2 68  ? 293.892 300.946 418.201 1.00 87.64  ? 68  GLU H CG  1 
ATOM 3472 C CD  . GLU D 2 68  ? 293.894 302.394 417.760 1.00 87.64  ? 68  GLU H CD  1 
ATOM 3473 O OE1 . GLU D 2 68  ? 293.093 303.182 418.304 1.00 87.64  ? 68  GLU H OE1 1 
ATOM 3474 O OE2 . GLU D 2 68  ? 294.699 302.747 416.873 1.00 87.64  ? 68  GLU H OE2 1 
ATOM 3475 N N   . GLY D 2 69  ? 294.320 298.843 421.511 1.00 89.50  ? 69  GLY H N   1 
ATOM 3476 C CA  . GLY D 2 69  ? 295.613 298.436 422.027 1.00 89.50  ? 69  GLY H CA  1 
ATOM 3477 C C   . GLY D 2 69  ? 295.791 296.943 422.190 1.00 89.50  ? 69  GLY H C   1 
ATOM 3478 O O   . GLY D 2 69  ? 296.926 296.462 422.257 1.00 89.50  ? 69  GLY H O   1 
ATOM 3479 N N   . ARG D 2 70  ? 294.695 296.184 422.251 1.00 90.05  ? 70  ARG H N   1 
ATOM 3480 C CA  . ARG D 2 70  ? 294.785 294.807 422.705 1.00 90.05  ? 70  ARG H CA  1 
ATOM 3481 C C   . ARG D 2 70  ? 293.982 293.787 421.906 1.00 90.05  ? 70  ARG H C   1 
ATOM 3482 O O   . ARG D 2 70  ? 294.152 292.588 422.151 1.00 90.05  ? 70  ARG H O   1 
ATOM 3483 C CB  . ARG D 2 70  ? 294.378 294.726 424.186 1.00 90.05  ? 70  ARG H CB  1 
ATOM 3484 C CG  . ARG D 2 70  ? 292.945 295.111 424.481 1.00 90.05  ? 70  ARG H CG  1 
ATOM 3485 C CD  . ARG D 2 70  ? 292.722 295.232 425.979 1.00 90.05  ? 70  ARG H CD  1 
ATOM 3486 N NE  . ARG D 2 70  ? 291.313 295.398 426.313 1.00 90.05  ? 70  ARG H NE  1 
ATOM 3487 C CZ  . ARG D 2 70  ? 290.690 296.566 426.364 1.00 90.05  ? 70  ARG H CZ  1 
ATOM 3488 N NH1 . ARG D 2 70  ? 291.349 297.684 426.102 1.00 90.05  ? 70  ARG H NH1 1 
ATOM 3489 N NH2 . ARG D 2 70  ? 289.404 296.617 426.675 1.00 90.05  ? 70  ARG H NH2 1 
ATOM 3490 N N   . PHE D 2 71  ? 293.127 294.198 420.972 1.00 86.49  ? 71  PHE H N   1 
ATOM 3491 C CA  . PHE D 2 71  ? 292.387 293.239 420.156 1.00 86.49  ? 71  PHE H CA  1 
ATOM 3492 C C   . PHE D 2 71  ? 292.863 293.293 418.710 1.00 86.49  ? 71  PHE H C   1 
ATOM 3493 O O   . PHE D 2 71  ? 293.350 294.322 418.237 1.00 86.49  ? 71  PHE H O   1 
ATOM 3494 C CB  . PHE D 2 71  ? 290.877 293.499 420.176 1.00 86.49  ? 71  PHE H CB  1 
ATOM 3495 C CG  . PHE D 2 71  ? 290.204 293.233 421.499 1.00 86.49  ? 71  PHE H CG  1 
ATOM 3496 C CD1 . PHE D 2 71  ? 290.850 292.564 422.523 1.00 86.49  ? 71  PHE H CD1 1 
ATOM 3497 C CD2 . PHE D 2 71  ? 288.897 293.644 421.702 1.00 86.49  ? 71  PHE H CD2 1 
ATOM 3498 C CE1 . PHE D 2 71  ? 290.212 292.331 423.726 1.00 86.49  ? 71  PHE H CE1 1 
ATOM 3499 C CE2 . PHE D 2 71  ? 288.255 293.413 422.897 1.00 86.49  ? 71  PHE H CE2 1 
ATOM 3500 C CZ  . PHE D 2 71  ? 288.914 292.758 423.910 1.00 86.49  ? 71  PHE H CZ  1 
ATOM 3501 N N   . THR D 2 72  ? 292.718 292.169 418.007 1.00 79.46  ? 72  THR H N   1 
ATOM 3502 C CA  . THR D 2 72  ? 292.891 292.117 416.562 1.00 79.46  ? 72  THR H CA  1 
ATOM 3503 C C   . THR D 2 72  ? 291.680 291.441 415.936 1.00 79.46  ? 72  THR H C   1 
ATOM 3504 O O   . THR D 2 72  ? 291.012 290.621 416.571 1.00 79.46  ? 72  THR H O   1 
ATOM 3505 C CB  . THR D 2 72  ? 294.160 291.362 416.131 1.00 79.46  ? 72  THR H CB  1 
ATOM 3506 O OG1 . THR D 2 72  ? 294.091 290.008 416.587 1.00 79.46  ? 72  THR H OG1 1 
ATOM 3507 C CG2 . THR D 2 72  ? 295.409 292.017 416.688 1.00 79.46  ? 72  THR H CG2 1 
ATOM 3508 N N   . ILE D 2 73  ? 291.408 291.786 414.680 1.00 72.26  ? 73  ILE H N   1 
ATOM 3509 C CA  . ILE D 2 73  ? 290.296 291.228 413.920 1.00 72.26  ? 73  ILE H CA  1 
ATOM 3510 C C   . ILE D 2 73  ? 290.836 290.693 412.598 1.00 72.26  ? 73  ILE H C   1 
ATOM 3511 O O   . ILE D 2 73  ? 291.766 291.265 412.018 1.00 72.26  ? 73  ILE H O   1 
ATOM 3512 C CB  . ILE D 2 73  ? 289.180 292.283 413.717 1.00 72.26  ? 73  ILE H CB  1 
ATOM 3513 C CG1 . ILE D 2 73  ? 287.946 291.701 413.026 1.00 72.26  ? 73  ILE H CG1 1 
ATOM 3514 C CG2 . ILE D 2 73  ? 289.686 293.517 413.014 1.00 72.26  ? 73  ILE H CG2 1 
ATOM 3515 C CD1 . ILE D 2 73  ? 286.786 292.656 412.983 1.00 72.26  ? 73  ILE H CD1 1 
ATOM 3516 N N   . SER D 2 74  ? 290.295 289.563 412.151 1.00 69.72  ? 74  SER H N   1 
ATOM 3517 C CA  . SER D 2 74  ? 290.759 288.933 410.926 1.00 69.72  ? 74  SER H CA  1 
ATOM 3518 C C   . SER D 2 74  ? 289.624 288.124 410.321 1.00 69.72  ? 74  SER H C   1 
ATOM 3519 O O   . SER D 2 74  ? 288.571 287.936 410.932 1.00 69.72  ? 74  SER H O   1 
ATOM 3520 C CB  . SER D 2 74  ? 291.977 288.043 411.182 1.00 69.72  ? 74  SER H CB  1 
ATOM 3521 O OG  . SER D 2 74  ? 291.632 286.937 411.994 1.00 69.72  ? 74  SER H OG  1 
ATOM 3522 N N   . ARG D 2 75  ? 289.853 287.637 409.106 1.00 64.48  ? 75  ARG H N   1 
ATOM 3523 C CA  . ARG D 2 75  ? 288.836 286.881 408.398 1.00 64.48  ? 75  ARG H CA  1 
ATOM 3524 C C   . ARG D 2 75  ? 289.502 285.876 407.474 1.00 64.48  ? 75  ARG H C   1 
ATOM 3525 O O   . ARG D 2 75  ? 290.670 286.018 407.106 1.00 64.48  ? 75  ARG H O   1 
ATOM 3526 C CB  . ARG D 2 75  ? 287.908 287.812 407.615 1.00 64.48  ? 75  ARG H CB  1 
ATOM 3527 C CG  . ARG D 2 75  ? 288.613 288.650 406.570 1.00 64.48  ? 75  ARG H CG  1 
ATOM 3528 C CD  . ARG D 2 75  ? 287.662 289.642 405.947 1.00 64.48  ? 75  ARG H CD  1 
ATOM 3529 N NE  . ARG D 2 75  ? 286.656 289.006 405.109 1.00 64.48  ? 75  ARG H NE  1 
ATOM 3530 C CZ  . ARG D 2 75  ? 285.526 289.590 404.738 1.00 64.48  ? 75  ARG H CZ  1 
ATOM 3531 N NH1 . ARG D 2 75  ? 285.248 290.814 405.147 1.00 64.48  ? 75  ARG H NH1 1 
ATOM 3532 N NH2 . ARG D 2 75  ? 284.666 288.946 403.966 1.00 64.48  ? 75  ARG H NH2 1 
ATOM 3533 N N   . ASP D 2 76  ? 288.738 284.851 407.108 1.00 69.60  ? 76  ASP H N   1 
ATOM 3534 C CA  . ASP D 2 76  ? 289.197 283.799 406.207 1.00 69.60  ? 76  ASP H CA  1 
ATOM 3535 C C   . ASP D 2 76  ? 288.148 283.641 405.117 1.00 69.60  ? 76  ASP H C   1 
ATOM 3536 O O   . ASP D 2 76  ? 287.102 283.027 405.345 1.00 69.60  ? 76  ASP H O   1 
ATOM 3537 C CB  . ASP D 2 76  ? 289.413 282.485 406.955 1.00 69.60  ? 76  ASP H CB  1 
ATOM 3538 C CG  . ASP D 2 76  ? 290.197 281.467 406.147 1.00 69.60  ? 76  ASP H CG  1 
ATOM 3539 O OD1 . ASP D 2 76  ? 290.588 281.766 405.000 1.00 69.60  ? 76  ASP H OD1 1 
ATOM 3540 O OD2 . ASP D 2 76  ? 290.427 280.356 406.666 1.00 69.60  ? 76  ASP H OD2 1 
ATOM 3541 N N   . ASN D 2 77  ? 288.439 284.169 403.932 1.00 67.40  ? 77  ASN H N   1 
ATOM 3542 C CA  . ASN D 2 77  ? 287.461 284.199 402.854 1.00 67.40  ? 77  ASN H CA  1 
ATOM 3543 C C   . ASN D 2 77  ? 287.272 282.853 402.169 1.00 67.40  ? 77  ASN H C   1 
ATOM 3544 O O   . ASN D 2 77  ? 286.357 282.722 401.350 1.00 67.40  ? 77  ASN H O   1 
ATOM 3545 C CB  . ASN D 2 77  ? 287.858 285.252 401.825 1.00 67.40  ? 77  ASN H CB  1 
ATOM 3546 C CG  . ASN D 2 77  ? 287.677 286.659 402.339 1.00 67.40  ? 77  ASN H CG  1 
ATOM 3547 O OD1 . ASN D 2 77  ? 286.692 286.963 403.005 1.00 67.40  ? 77  ASN H OD1 1 
ATOM 3548 N ND2 . ASN D 2 77  ? 288.621 287.534 402.019 1.00 67.40  ? 77  ASN H ND2 1 
ATOM 3549 N N   . ALA D 2 78  ? 288.100 281.858 402.474 1.00 70.25  ? 78  ALA H N   1 
ATOM 3550 C CA  . ALA D 2 78  ? 287.911 280.525 401.920 1.00 70.25  ? 78  ALA H CA  1 
ATOM 3551 C C   . ALA D 2 78  ? 287.153 279.604 402.863 1.00 70.25  ? 78  ALA H C   1 
ATOM 3552 O O   . ALA D 2 78  ? 286.495 278.664 402.402 1.00 70.25  ? 78  ALA H O   1 
ATOM 3553 C CB  . ALA D 2 78  ? 289.262 279.902 401.568 1.00 70.25  ? 78  ALA H CB  1 
ATOM 3554 N N   . LYS D 2 79  ? 287.232 279.846 404.169 1.00 72.18  ? 79  LYS H N   1 
ATOM 3555 C CA  . LYS D 2 79  ? 286.469 279.092 405.152 1.00 72.18  ? 79  LYS H CA  1 
ATOM 3556 C C   . LYS D 2 79  ? 285.268 279.859 405.680 1.00 72.18  ? 79  LYS H C   1 
ATOM 3557 O O   . LYS D 2 79  ? 284.569 279.345 406.560 1.00 72.18  ? 79  LYS H O   1 
ATOM 3558 C CB  . LYS D 2 79  ? 287.364 278.683 406.325 1.00 72.18  ? 79  LYS H CB  1 
ATOM 3559 C CG  . LYS D 2 79  ? 288.413 277.651 405.983 1.00 72.18  ? 79  LYS H CG  1 
ATOM 3560 C CD  . LYS D 2 79  ? 289.184 277.251 407.226 1.00 72.18  ? 79  LYS H CD  1 
ATOM 3561 C CE  . LYS D 2 79  ? 290.238 276.206 406.918 1.00 72.18  ? 79  LYS H CE  1 
ATOM 3562 N NZ  . LYS D 2 79  ? 290.974 275.806 408.147 1.00 72.18  ? 79  LYS H NZ  1 
ATOM 3563 N N   . ASN D 2 80  ? 285.044 281.082 405.182 1.00 69.45  ? 80  ASN H N   1 
ATOM 3564 C CA  . ASN D 2 80  ? 283.885 281.928 405.493 1.00 69.45  ? 80  ASN H CA  1 
ATOM 3565 C C   . ASN D 2 80  ? 283.792 282.282 406.976 1.00 69.45  ? 80  ASN H C   1 
ATOM 3566 O O   . ASN D 2 80  ? 282.699 282.464 407.508 1.00 69.45  ? 80  ASN H O   1 
ATOM 3567 C CB  . ASN D 2 80  ? 282.575 281.288 405.018 1.00 69.45  ? 80  ASN H CB  1 
ATOM 3568 C CG  . ASN D 2 80  ? 282.483 281.202 403.514 1.00 69.45  ? 80  ASN H CG  1 
ATOM 3569 O OD1 . ASN D 2 80  ? 282.858 282.128 402.802 1.00 69.45  ? 80  ASN H OD1 1 
ATOM 3570 N ND2 . ASN D 2 80  ? 281.982 280.082 403.017 1.00 69.45  ? 80  ASN H ND2 1 
ATOM 3571 N N   . ASN D 2 81  ? 284.923 282.395 407.662 1.00 69.79  ? 81  ASN H N   1 
ATOM 3572 C CA  . ASN D 2 81  ? 284.931 282.695 409.085 1.00 69.79  ? 81  ASN H CA  1 
ATOM 3573 C C   . ASN D 2 81  ? 285.338 284.141 409.324 1.00 69.79  ? 81  ASN H C   1 
ATOM 3574 O O   . ASN D 2 81  ? 285.902 284.805 408.454 1.00 69.79  ? 81  ASN H O   1 
ATOM 3575 C CB  . ASN D 2 81  ? 285.870 281.755 409.841 1.00 69.79  ? 81  ASN H CB  1 
ATOM 3576 C CG  . ASN D 2 81  ? 285.328 280.349 409.935 1.00 69.79  ? 81  ASN H CG  1 
ATOM 3577 O OD1 . ASN D 2 81  ? 284.142 280.143 410.188 1.00 69.79  ? 81  ASN H OD1 1 
ATOM 3578 N ND2 . ASN D 2 81  ? 286.196 279.370 409.725 1.00 69.79  ? 81  ASN H ND2 1 
ATOM 3579 N N   . LEU D 2 82  ? 285.059 284.618 410.535 1.00 70.21  ? 82  LEU H N   1 
ATOM 3580 C CA  . LEU D 2 82  ? 285.288 286.012 410.907 1.00 70.21  ? 82  LEU H CA  1 
ATOM 3581 C C   . LEU D 2 82  ? 285.695 286.037 412.375 1.00 70.21  ? 82  LEU H C   1 
ATOM 3582 O O   . LEU D 2 82  ? 284.848 285.874 413.256 1.00 70.21  ? 82  LEU H O   1 
ATOM 3583 C CB  . LEU D 2 82  ? 284.035 286.846 410.631 1.00 70.21  ? 82  LEU H CB  1 
ATOM 3584 C CG  . LEU D 2 82  ? 283.988 288.374 410.706 1.00 70.21  ? 82  LEU H CG  1 
ATOM 3585 C CD1 . LEU D 2 82  ? 283.639 288.879 412.076 1.00 70.21  ? 82  LEU H CD1 1 
ATOM 3586 C CD2 . LEU D 2 82  ? 285.318 288.952 410.283 1.00 70.21  ? 82  LEU H CD2 1 
ATOM 3587 N N   . TYR D 2 83  ? 286.984 286.241 412.635 1.00 72.88  ? 83  TYR H N   1 
ATOM 3588 C CA  . TYR D 2 83  ? 287.592 285.996 413.935 1.00 72.88  ? 83  TYR H CA  1 
ATOM 3589 C C   . TYR D 2 83  ? 287.734 287.285 414.737 1.00 72.88  ? 83  TYR H C   1 
ATOM 3590 O O   . TYR D 2 83  ? 287.549 288.390 414.227 1.00 72.88  ? 83  TYR H O   1 
ATOM 3591 C CB  . TYR D 2 83  ? 288.966 285.346 413.759 1.00 72.88  ? 83  TYR H CB  1 
ATOM 3592 C CG  . TYR D 2 83  ? 288.938 284.018 413.053 1.00 72.88  ? 83  TYR H CG  1 
ATOM 3593 C CD1 . TYR D 2 83  ? 288.615 282.856 413.730 1.00 72.88  ? 83  TYR H CD1 1 
ATOM 3594 C CD2 . TYR D 2 83  ? 289.238 283.931 411.705 1.00 72.88  ? 83  TYR H CD2 1 
ATOM 3595 C CE1 . TYR D 2 83  ? 288.591 281.641 413.081 1.00 72.88  ? 83  TYR H CE1 1 
ATOM 3596 C CE2 . TYR D 2 83  ? 289.218 282.726 411.048 1.00 72.88  ? 83  TYR H CE2 1 
ATOM 3597 C CZ  . TYR D 2 83  ? 288.895 281.585 411.740 1.00 72.88  ? 83  TYR H CZ  1 
ATOM 3598 O OH  . TYR D 2 83  ? 288.873 280.381 411.081 1.00 72.88  ? 83  TYR H OH  1 
ATOM 3599 N N   . LEU D 2 84  ? 288.079 287.124 416.016 1.00 78.02  ? 84  LEU H N   1 
ATOM 3600 C CA  . LEU D 2 84  ? 288.393 288.260 416.884 1.00 78.02  ? 84  LEU H CA  1 
ATOM 3601 C C   . LEU D 2 84  ? 289.291 287.741 417.998 1.00 78.02  ? 84  LEU H C   1 
ATOM 3602 O O   . LEU D 2 84  ? 288.797 287.118 418.942 1.00 78.02  ? 84  LEU H O   1 
ATOM 3603 C CB  . LEU D 2 84  ? 287.115 288.883 417.442 1.00 78.02  ? 84  LEU H CB  1 
ATOM 3604 C CG  . LEU D 2 84  ? 287.044 290.300 418.037 1.00 78.02  ? 84  LEU H CG  1 
ATOM 3605 C CD1 . LEU D 2 84  ? 287.540 290.401 419.452 1.00 78.02  ? 84  LEU H CD1 1 
ATOM 3606 C CD2 . LEU D 2 84  ? 287.800 291.276 417.161 1.00 78.02  ? 84  LEU H CD2 1 
ATOM 3607 N N   . GLN D 2 85  ? 290.596 287.992 417.895 1.00 83.60  ? 85  GLN H N   1 
ATOM 3608 C CA  . GLN D 2 85  ? 291.543 287.595 418.929 1.00 83.60  ? 85  GLN H CA  1 
ATOM 3609 C C   . GLN D 2 85  ? 291.543 288.625 420.048 1.00 83.60  ? 85  GLN H C   1 
ATOM 3610 O O   . GLN D 2 85  ? 291.582 289.830 419.789 1.00 83.60  ? 85  GLN H O   1 
ATOM 3611 C CB  . GLN D 2 85  ? 292.954 287.447 418.366 1.00 83.60  ? 85  GLN H CB  1 
ATOM 3612 C CG  . GLN D 2 85  ? 293.112 286.296 417.402 1.00 83.60  ? 85  GLN H CG  1 
ATOM 3613 C CD  . GLN D 2 85  ? 294.524 286.167 416.876 1.00 83.60  ? 85  GLN H CD  1 
ATOM 3614 O OE1 . GLN D 2 85  ? 295.397 286.970 417.205 1.00 83.60  ? 85  GLN H OE1 1 
ATOM 3615 N NE2 . GLN D 2 85  ? 294.757 285.156 416.048 1.00 83.60  ? 85  GLN H NE2 1 
ATOM 3616 N N   . MET D 2 86  ? 291.517 288.147 421.285 1.00 88.74  ? 86  MET H N   1 
ATOM 3617 C CA  . MET D 2 86  ? 291.385 289.006 422.448 1.00 88.74  ? 86  MET H CA  1 
ATOM 3618 C C   . MET D 2 86  ? 292.615 288.882 423.333 1.00 88.74  ? 86  MET H C   1 
ATOM 3619 O O   . MET D 2 86  ? 293.280 287.843 423.354 1.00 88.74  ? 86  MET H O   1 
ATOM 3620 C CB  . MET D 2 86  ? 290.137 288.645 423.245 1.00 88.74  ? 86  MET H CB  1 
ATOM 3621 C CG  . MET D 2 86  ? 288.870 288.818 422.454 1.00 88.74  ? 86  MET H CG  1 
ATOM 3622 S SD  . MET D 2 86  ? 287.400 288.285 423.330 1.00 88.74  ? 86  MET H SD  1 
ATOM 3623 C CE  . MET D 2 86  ? 287.282 289.585 424.538 1.00 88.74  ? 86  MET H CE  1 
ATOM 3624 N N   . SER D 2 87  ? 292.912 289.953 424.062 1.00 92.40  ? 87  SER H N   1 
ATOM 3625 C CA  . SER D 2 87  ? 294.020 289.939 425.003 1.00 92.40  ? 87  SER H CA  1 
ATOM 3626 C C   . SER D 2 87  ? 293.772 290.972 426.088 1.00 92.40  ? 87  SER H C   1 
ATOM 3627 O O   . SER D 2 87  ? 293.074 291.965 425.872 1.00 92.40  ? 87  SER H O   1 
ATOM 3628 C CB  . SER D 2 87  ? 295.359 290.211 424.309 1.00 92.40  ? 87  SER H CB  1 
ATOM 3629 O OG  . SER D 2 87  ? 295.411 291.528 423.799 1.00 92.40  ? 87  SER H OG  1 
ATOM 3630 N N   . HIS D 2 88  ? 294.284 290.661 427.282 1.00 95.34  ? 88  HIS H N   1 
ATOM 3631 C CA  . HIS D 2 88  ? 294.480 291.536 428.439 1.00 95.34  ? 88  HIS H CA  1 
ATOM 3632 C C   . HIS D 2 88  ? 293.209 291.927 429.187 1.00 95.34  ? 88  HIS H C   1 
ATOM 3633 O O   . HIS D 2 88  ? 293.329 292.535 430.257 1.00 95.34  ? 88  HIS H O   1 
ATOM 3634 C CB  . HIS D 2 88  ? 295.235 292.809 428.039 1.00 95.34  ? 88  HIS H CB  1 
ATOM 3635 C CG  . HIS D 2 88  ? 296.608 292.552 427.505 1.00 95.34  ? 88  HIS H CG  1 
ATOM 3636 N ND1 . HIS D 2 88  ? 297.653 292.142 428.304 1.00 95.34  ? 88  HIS H ND1 1 
ATOM 3637 C CD2 . HIS D 2 88  ? 297.110 292.659 426.253 1.00 95.34  ? 88  HIS H CD2 1 
ATOM 3638 C CE1 . HIS D 2 88  ? 298.738 291.996 427.565 1.00 95.34  ? 88  HIS H CE1 1 
ATOM 3639 N NE2 . HIS D 2 88  ? 298.436 292.307 426.318 1.00 95.34  ? 88  HIS H NE2 1 
ATOM 3640 N N   . LEU D 2 89  ? 292.035 291.637 428.608 1.00 96.21  ? 89  LEU H N   1 
ATOM 3641 C CA  . LEU D 2 89  ? 290.726 291.406 429.257 1.00 96.21  ? 89  LEU H CA  1 
ATOM 3642 C C   . LEU D 2 89  ? 290.451 292.261 430.496 1.00 96.21  ? 89  LEU H C   1 
ATOM 3643 O O   . LEU D 2 89  ? 290.206 291.757 431.592 1.00 96.21  ? 89  LEU H O   1 
ATOM 3644 C CB  . LEU D 2 89  ? 290.569 289.928 429.593 1.00 96.21  ? 89  LEU H CB  1 
ATOM 3645 C CG  . LEU D 2 89  ? 290.372 289.062 428.355 1.00 96.21  ? 89  LEU H CG  1 
ATOM 3646 C CD1 . LEU D 2 89  ? 290.367 287.596 428.706 1.00 96.21  ? 89  LEU H CD1 1 
ATOM 3647 C CD2 . LEU D 2 89  ? 289.065 289.445 427.728 1.00 96.21  ? 89  LEU H CD2 1 
ATOM 3648 N N   . LYS D 2 90  ? 290.483 293.578 430.307 1.00 95.34  ? 90  LYS H N   1 
ATOM 3649 C CA  . LYS D 2 90  ? 290.529 294.486 431.448 1.00 95.34  ? 90  LYS H CA  1 
ATOM 3650 C C   . LYS D 2 90  ? 289.175 294.729 432.110 1.00 95.34  ? 90  LYS H C   1 
ATOM 3651 O O   . LYS D 2 90  ? 288.762 295.883 432.268 1.00 95.34  ? 90  LYS H O   1 
ATOM 3652 C CB  . LYS D 2 90  ? 291.140 295.824 431.025 1.00 95.34  ? 90  LYS H CB  1 
ATOM 3653 C CG  . LYS D 2 90  ? 292.623 295.736 430.704 1.00 95.34  ? 90  LYS H CG  1 
ATOM 3654 C CD  . LYS D 2 90  ? 293.247 297.103 430.480 1.00 95.34  ? 90  LYS H CD  1 
ATOM 3655 C CE  . LYS D 2 90  ? 292.875 297.673 429.127 1.00 95.34  ? 90  LYS H CE  1 
ATOM 3656 N NZ  . LYS D 2 90  ? 293.597 298.941 428.852 1.00 95.34  ? 90  LYS H NZ  1 
ATOM 3657 N N   . SER D 2 91  ? 288.473 293.656 432.482 1.00 96.04  ? 91  SER H N   1 
ATOM 3658 C CA  . SER D 2 91  ? 287.361 293.588 433.434 1.00 96.04  ? 91  SER H CA  1 
ATOM 3659 C C   . SER D 2 91  ? 286.113 294.372 433.039 1.00 96.04  ? 91  SER H C   1 
ATOM 3660 O O   . SER D 2 91  ? 285.137 294.358 433.793 1.00 96.04  ? 91  SER H O   1 
ATOM 3661 C CB  . SER D 2 91  ? 287.769 294.045 434.844 1.00 96.04  ? 91  SER H CB  1 
ATOM 3662 O OG  . SER D 2 91  ? 288.002 295.441 434.893 1.00 96.04  ? 91  SER H OG  1 
ATOM 3663 N N   . GLU D 2 92  ? 286.100 295.047 431.895 1.00 96.60  ? 92  GLU H N   1 
ATOM 3664 C CA  . GLU D 2 92  ? 284.956 295.836 431.467 1.00 96.60  ? 92  GLU H CA  1 
ATOM 3665 C C   . GLU D 2 92  ? 284.214 295.215 430.303 1.00 96.60  ? 92  GLU H C   1 
ATOM 3666 O O   . GLU D 2 92  ? 283.032 295.501 430.110 1.00 96.60  ? 92  GLU H O   1 
ATOM 3667 C CB  . GLU D 2 92  ? 285.405 297.244 431.066 1.00 96.60  ? 92  GLU H CB  1 
ATOM 3668 C CG  . GLU D 2 92  ? 285.978 298.065 432.204 1.00 96.60  ? 92  GLU H CG  1 
ATOM 3669 C CD  . GLU D 2 92  ? 286.483 299.412 431.741 1.00 96.60  ? 92  GLU H CD  1 
ATOM 3670 O OE1 . GLU D 2 92  ? 286.504 299.648 430.515 1.00 96.60  ? 92  GLU H OE1 1 
ATOM 3671 O OE2 . GLU D 2 92  ? 286.862 300.235 432.601 1.00 96.60  ? 92  GLU H OE2 1 
ATOM 3672 N N   . ASP D 2 93  ? 284.891 294.368 429.530 1.00 94.34  ? 93  ASP H N   1 
ATOM 3673 C CA  . ASP D 2 93  ? 284.323 293.721 428.352 1.00 94.34  ? 93  ASP H CA  1 
ATOM 3674 C C   . ASP D 2 93  ? 283.689 292.390 428.748 1.00 94.34  ? 93  ASP H C   1 
ATOM 3675 O O   . ASP D 2 93  ? 284.292 291.319 428.683 1.00 94.34  ? 93  ASP H O   1 
ATOM 3676 C CB  . ASP D 2 93  ? 285.399 293.576 427.283 1.00 94.34  ? 93  ASP H CB  1 
ATOM 3677 C CG  . ASP D 2 93  ? 286.709 293.061 427.840 1.00 94.34  ? 93  ASP H CG  1 
ATOM 3678 O OD1 . ASP D 2 93  ? 286.796 292.879 429.072 1.00 94.34  ? 93  ASP H OD1 1 
ATOM 3679 O OD2 . ASP D 2 93  ? 287.656 292.857 427.054 1.00 94.34  ? 93  ASP H OD2 1 
ATOM 3680 N N   . THR D 2 94  ? 282.427 292.470 429.168 1.00 93.45  ? 94  THR H N   1 
ATOM 3681 C CA  . THR D 2 94  ? 281.648 291.291 429.530 1.00 93.45  ? 94  THR H CA  1 
ATOM 3682 C C   . THR D 2 94  ? 280.379 291.217 428.690 1.00 93.45  ? 94  THR H C   1 
ATOM 3683 O O   . THR D 2 94  ? 279.287 290.999 429.221 1.00 93.45  ? 94  THR H O   1 
ATOM 3684 C CB  . THR D 2 94  ? 281.286 291.301 431.017 1.00 93.45  ? 94  THR H CB  1 
ATOM 3685 O OG1 . THR D 2 94  ? 280.499 292.461 431.312 1.00 93.45  ? 94  THR H OG1 1 
ATOM 3686 C CG2 . THR D 2 94  ? 282.535 291.298 431.886 1.00 93.45  ? 94  THR H CG2 1 
ATOM 3687 N N   . ALA D 2 95  ? 280.518 291.394 427.384 1.00 90.14  ? 95  ALA H N   1 
ATOM 3688 C CA  . ALA D 2 95  ? 279.406 291.613 426.480 1.00 90.14  ? 95  ALA H CA  1 
ATOM 3689 C C   . ALA D 2 95  ? 278.956 290.318 425.800 1.00 90.14  ? 95  ALA H C   1 
ATOM 3690 O O   . ALA D 2 95  ? 279.329 289.213 426.200 1.00 90.14  ? 95  ALA H O   1 
ATOM 3691 C CB  . ALA D 2 95  ? 279.794 292.673 425.458 1.00 90.14  ? 95  ALA H CB  1 
ATOM 3692 N N   . ILE D 2 96  ? 278.126 290.461 424.763 1.00 85.99  ? 96  ILE H N   1 
ATOM 3693 C CA  . ILE D 2 96  ? 277.514 289.341 424.055 1.00 85.99  ? 96  ILE H CA  1 
ATOM 3694 C C   . ILE D 2 96  ? 278.205 289.155 422.703 1.00 85.99  ? 96  ILE H C   1 
ATOM 3695 O O   . ILE D 2 96  ? 278.234 288.045 422.160 1.00 85.99  ? 96  ILE H O   1 
ATOM 3696 C CB  . ILE D 2 96  ? 275.996 289.573 423.911 1.00 85.99  ? 96  ILE H CB  1 
ATOM 3697 C CG1 . ILE D 2 96  ? 275.384 289.815 425.285 1.00 85.99  ? 96  ILE H CG1 1 
ATOM 3698 C CG2 . ILE D 2 96  ? 275.278 288.368 423.332 1.00 85.99  ? 96  ILE H CG2 1 
ATOM 3699 C CD1 . ILE D 2 96  ? 273.950 290.271 425.237 1.00 85.99  ? 96  ILE H CD1 1 
ATOM 3700 N N   . TYR D 2 97  ? 278.781 290.239 422.167 1.00 84.26  ? 97  TYR H N   1 
ATOM 3701 C CA  . TYR D 2 97  ? 279.641 290.238 420.973 1.00 84.26  ? 97  TYR H CA  1 
ATOM 3702 C C   . TYR D 2 97  ? 278.914 289.703 419.733 1.00 84.26  ? 97  TYR H C   1 
ATOM 3703 O O   . TYR D 2 97  ? 279.203 288.621 419.226 1.00 84.26  ? 97  TYR H O   1 
ATOM 3704 C CB  . TYR D 2 97  ? 280.936 289.447 421.198 1.00 84.26  ? 97  TYR H CB  1 
ATOM 3705 C CG  . TYR D 2 97  ? 281.942 290.109 422.100 1.00 84.26  ? 97  TYR H CG  1 
ATOM 3706 C CD1 . TYR D 2 97  ? 281.786 291.416 422.506 1.00 84.26  ? 97  TYR H CD1 1 
ATOM 3707 C CD2 . TYR D 2 97  ? 283.066 289.430 422.513 1.00 84.26  ? 97  TYR H CD2 1 
ATOM 3708 C CE1 . TYR D 2 97  ? 282.706 292.026 423.323 1.00 84.26  ? 97  TYR H CE1 1 
ATOM 3709 C CE2 . TYR D 2 97  ? 283.992 290.028 423.322 1.00 84.26  ? 97  TYR H CE2 1 
ATOM 3710 C CZ  . TYR D 2 97  ? 283.810 291.327 423.724 1.00 84.26  ? 97  TYR H CZ  1 
ATOM 3711 O OH  . TYR D 2 97  ? 284.740 291.921 424.534 1.00 84.26  ? 97  TYR H OH  1 
ATOM 3712 N N   . HIS D 2 98  ? 277.942 290.486 419.275 1.00 79.11  ? 98  HIS H N   1 
ATOM 3713 C CA  . HIS D 2 98  ? 277.239 290.164 418.042 1.00 79.11  ? 98  HIS H CA  1 
ATOM 3714 C C   . HIS D 2 98  ? 278.161 290.267 416.831 1.00 79.11  ? 98  HIS H C   1 
ATOM 3715 O O   . HIS D 2 98  ? 279.123 291.037 416.814 1.00 79.11  ? 98  HIS H O   1 
ATOM 3716 C CB  . HIS D 2 98  ? 276.049 291.093 417.851 1.00 79.11  ? 98  HIS H CB  1 
ATOM 3717 C CG  . HIS D 2 98  ? 274.984 290.927 418.884 1.00 79.11  ? 98  HIS H CG  1 
ATOM 3718 N ND1 . HIS D 2 98  ? 274.090 289.880 418.867 1.00 79.11  ? 98  HIS H ND1 1 
ATOM 3719 C CD2 . HIS D 2 98  ? 274.673 291.673 419.969 1.00 79.11  ? 98  HIS H CD2 1 
ATOM 3720 C CE1 . HIS D 2 98  ? 273.269 289.992 419.895 1.00 79.11  ? 98  HIS H CE1 1 
ATOM 3721 N NE2 . HIS D 2 98  ? 273.603 291.069 420.581 1.00 79.11  ? 98  HIS H NE2 1 
ATOM 3722 N N   . CYS D 2 99  ? 277.850 289.473 415.813 1.00 76.16  ? 99  CYS H N   1 
ATOM 3723 C CA  . CYS D 2 99  ? 278.558 289.464 414.538 1.00 76.16  ? 99  CYS H CA  1 
ATOM 3724 C C   . CYS D 2 99  ? 277.641 290.076 413.489 1.00 76.16  ? 99  CYS H C   1 
ATOM 3725 O O   . CYS D 2 99  ? 276.587 289.512 413.183 1.00 76.16  ? 99  CYS H O   1 
ATOM 3726 C CB  . CYS D 2 99  ? 278.954 288.036 414.159 1.00 76.16  ? 99  CYS H CB  1 
ATOM 3727 S SG  . CYS D 2 99  ? 279.839 287.809 412.607 1.00 76.16  ? 99  CYS H SG  1 
ATOM 3728 N N   . ALA D 2 100 ? 278.030 291.224 412.949 1.00 69.64  ? 100 ALA H N   1 
ATOM 3729 C CA  . ALA D 2 100 ? 277.181 291.976 412.041 1.00 69.64  ? 100 ALA H CA  1 
ATOM 3730 C C   . ALA D 2 100 ? 277.709 291.892 410.617 1.00 69.64  ? 100 ALA H C   1 
ATOM 3731 O O   . ALA D 2 100 ? 278.890 291.631 410.384 1.00 69.64  ? 100 ALA H O   1 
ATOM 3732 C CB  . ALA D 2 100 ? 277.083 293.443 412.466 1.00 69.64  ? 100 ALA H CB  1 
ATOM 3733 N N   . ARG D 2 101 ? 276.813 292.123 409.664 1.00 64.68  ? 101 ARG H N   1 
ATOM 3734 C CA  . ARG D 2 101 ? 277.151 292.190 408.251 1.00 64.68  ? 101 ARG H CA  1 
ATOM 3735 C C   . ARG D 2 101 ? 277.055 293.648 407.836 1.00 64.68  ? 101 ARG H C   1 
ATOM 3736 O O   . ARG D 2 101 ? 276.015 294.281 408.032 1.00 64.68  ? 101 ARG H O   1 
ATOM 3737 C CB  . ARG D 2 101 ? 276.195 291.338 407.414 1.00 64.68  ? 101 ARG H CB  1 
ATOM 3738 C CG  . ARG D 2 101 ? 276.771 290.833 406.100 1.00 64.68  ? 101 ARG H CG  1 
ATOM 3739 C CD  . ARG D 2 101 ? 276.700 291.796 404.946 1.00 64.68  ? 101 ARG H CD  1 
ATOM 3740 N NE  . ARG D 2 101 ? 275.353 292.223 404.589 1.00 64.68  ? 101 ARG H NE  1 
ATOM 3741 C CZ  . ARG D 2 101 ? 274.533 291.541 403.798 1.00 64.68  ? 101 ARG H CZ  1 
ATOM 3742 N NH1 . ARG D 2 101 ? 273.334 292.023 403.518 1.00 64.68  ? 101 ARG H NH1 1 
ATOM 3743 N NH2 . ARG D 2 101 ? 274.903 290.377 403.287 1.00 64.68  ? 101 ARG H NH2 1 
ATOM 3744 N N   . ASP D 2 102 ? 278.120 294.176 407.251 1.00 65.10  ? 102 ASP H N   1 
ATOM 3745 C CA  . ASP D 2 102 ? 278.145 295.594 406.937 1.00 65.10  ? 102 ASP H CA  1 
ATOM 3746 C C   . ASP D 2 102 ? 277.355 295.904 405.677 1.00 65.10  ? 102 ASP H C   1 
ATOM 3747 O O   . ASP D 2 102 ? 277.235 295.084 404.767 1.00 65.10  ? 102 ASP H O   1 
ATOM 3748 C CB  . ASP D 2 102 ? 279.574 296.088 406.779 1.00 65.10  ? 102 ASP H CB  1 
ATOM 3749 C CG  . ASP D 2 102 ? 280.302 296.130 408.089 1.00 65.10  ? 102 ASP H CG  1 
ATOM 3750 O OD1 . ASP D 2 102 ? 279.625 296.222 409.129 1.00 65.10  ? 102 ASP H OD1 1 
ATOM 3751 O OD2 . ASP D 2 102 ? 281.544 296.108 408.101 1.00 65.10  ? 102 ASP H OD2 1 
ATOM 3752 N N   . SER D 2 103 ? 276.820 297.115 405.634 1.00 61.15  ? 103 SER H N   1 
ATOM 3753 C CA  . SER D 2 103 ? 276.035 297.565 404.504 1.00 61.15  ? 103 SER H CA  1 
ATOM 3754 C C   . SER D 2 103 ? 276.943 297.987 403.360 1.00 61.15  ? 103 SER H C   1 
ATOM 3755 O O   . SER D 2 103 ? 278.136 298.230 403.546 1.00 61.15  ? 103 SER H O   1 
ATOM 3756 C CB  . SER D 2 103 ? 275.154 298.734 404.912 1.00 61.15  ? 103 SER H CB  1 
ATOM 3757 O OG  . SER D 2 103 ? 275.965 299.843 405.243 1.00 61.15  ? 103 SER H OG  1 
ATOM 3758 N N   . SER D 2 104 ? 276.363 298.062 402.166 1.00 55.31  ? 104 SER H N   1 
ATOM 3759 C CA  . SER D 2 104 ? 277.097 298.538 401.004 1.00 55.31  ? 104 SER H CA  1 
ATOM 3760 C C   . SER D 2 104 ? 277.365 300.023 401.159 1.00 55.31  ? 104 SER H C   1 
ATOM 3761 O O   . SER D 2 104 ? 276.445 300.837 401.058 1.00 55.31  ? 104 SER H O   1 
ATOM 3762 C CB  . SER D 2 104 ? 276.297 298.286 399.731 1.00 55.31  ? 104 SER H CB  1 
ATOM 3763 O OG  . SER D 2 104 ? 276.063 296.908 399.530 1.00 55.31  ? 104 SER H OG  1 
ATOM 3764 N N   . GLY D 2 105 ? 278.613 300.386 401.420 1.00 58.77  ? 105 GLY H N   1 
ATOM 3765 C CA  . GLY D 2 105 ? 278.859 301.778 401.718 1.00 58.77  ? 105 GLY H CA  1 
ATOM 3766 C C   . GLY D 2 105 ? 280.240 302.143 402.208 1.00 58.77  ? 105 GLY H C   1 
ATOM 3767 O O   . GLY D 2 105 ? 281.200 301.399 401.995 1.00 58.77  ? 105 GLY H O   1 
ATOM 3768 N N   . TYR D 2 106 ? 280.355 303.303 402.858 1.00 66.14  ? 106 TYR H N   1 
ATOM 3769 C CA  . TYR D 2 106 ? 281.675 303.807 403.217 1.00 66.14  ? 106 TYR H CA  1 
ATOM 3770 C C   . TYR D 2 106 ? 281.933 303.672 404.714 1.00 66.14  ? 106 TYR H C   1 
ATOM 3771 O O   . TYR D 2 106 ? 283.062 303.394 405.130 1.00 66.14  ? 106 TYR H O   1 
ATOM 3772 C CB  . TYR D 2 106 ? 281.820 305.253 402.731 1.00 66.14  ? 106 TYR H CB  1 
ATOM 3773 C CG  . TYR D 2 106 ? 281.113 306.321 403.536 1.00 66.14  ? 106 TYR H CG  1 
ATOM 3774 C CD1 . TYR D 2 106 ? 279.736 306.440 403.516 1.00 66.14  ? 106 TYR H CD1 1 
ATOM 3775 C CD2 . TYR D 2 106 ? 281.841 307.283 404.221 1.00 66.14  ? 106 TYR H CD2 1 
ATOM 3776 C CE1 . TYR D 2 106 ? 279.100 307.432 404.227 1.00 66.14  ? 106 TYR H CE1 1 
ATOM 3777 C CE2 . TYR D 2 106 ? 281.215 308.286 404.926 1.00 66.14  ? 106 TYR H CE2 1 
ATOM 3778 C CZ  . TYR D 2 106 ? 279.847 308.351 404.930 1.00 66.14  ? 106 TYR H CZ  1 
ATOM 3779 O OH  . TYR D 2 106 ? 279.228 309.352 405.629 1.00 66.14  ? 106 TYR H OH  1 
ATOM 3780 N N   . PHE D 2 107 ? 280.906 303.868 405.537 1.00 69.60  ? 107 PHE H N   1 
ATOM 3781 C CA  . PHE D 2 107 ? 280.911 303.418 406.918 1.00 69.60  ? 107 PHE H CA  1 
ATOM 3782 C C   . PHE D 2 107 ? 279.601 302.684 407.165 1.00 69.60  ? 107 PHE H C   1 
ATOM 3783 O O   . PHE D 2 107 ? 278.560 303.095 406.642 1.00 69.60  ? 107 PHE H O   1 
ATOM 3784 C CB  . PHE D 2 107 ? 281.077 304.570 407.923 1.00 69.60  ? 107 PHE H CB  1 
ATOM 3785 C CG  . PHE D 2 107 ? 282.414 305.239 407.868 1.00 69.60  ? 107 PHE H CG  1 
ATOM 3786 C CD1 . PHE D 2 107 ? 283.564 304.529 408.143 1.00 69.60  ? 107 PHE H CD1 1 
ATOM 3787 C CD2 . PHE D 2 107 ? 282.511 306.598 407.645 1.00 69.60  ? 107 PHE H CD2 1 
ATOM 3788 C CE1 . PHE D 2 107 ? 284.798 305.147 408.111 1.00 69.60  ? 107 PHE H CE1 1 
ATOM 3789 C CE2 . PHE D 2 107 ? 283.738 307.226 407.620 1.00 69.60  ? 107 PHE H CE2 1 
ATOM 3790 C CZ  . PHE D 2 107 ? 284.881 306.497 407.852 1.00 69.60  ? 107 PHE H CZ  1 
ATOM 3791 N N   . PRO D 2 108 ? 279.612 301.594 407.931 1.00 68.84  ? 108 PRO H N   1 
ATOM 3792 C CA  . PRO D 2 108 ? 278.485 300.658 407.875 1.00 68.84  ? 108 PRO H CA  1 
ATOM 3793 C C   . PRO D 2 108 ? 277.303 301.084 408.727 1.00 68.84  ? 108 PRO H C   1 
ATOM 3794 O O   . PRO D 2 108 ? 277.432 301.896 409.641 1.00 68.84  ? 108 PRO H O   1 
ATOM 3795 C CB  . PRO D 2 108 ? 279.093 299.366 408.411 1.00 68.84  ? 108 PRO H CB  1 
ATOM 3796 C CG  . PRO D 2 108 ? 280.118 299.830 409.358 1.00 68.84  ? 108 PRO H CG  1 
ATOM 3797 C CD  . PRO D 2 108 ? 280.701 301.077 408.779 1.00 68.84  ? 108 PRO H CD  1 
ATOM 3798 N N   . TYR D 2 109 ? 276.137 300.504 408.428 1.00 70.15  ? 109 TYR H N   1 
ATOM 3799 C CA  . TYR D 2 109 ? 274.984 300.633 409.308 1.00 70.15  ? 109 TYR H CA  1 
ATOM 3800 C C   . TYR D 2 109 ? 274.297 299.310 409.639 1.00 70.15  ? 109 TYR H C   1 
ATOM 3801 O O   . TYR D 2 109 ? 273.119 299.330 410.007 1.00 70.15  ? 109 TYR H O   1 
ATOM 3802 C CB  . TYR D 2 109 ? 273.958 301.636 408.763 1.00 70.15  ? 109 TYR H CB  1 
ATOM 3803 C CG  . TYR D 2 109 ? 273.382 301.400 407.386 1.00 70.15  ? 109 TYR H CG  1 
ATOM 3804 C CD1 . TYR D 2 109 ? 272.287 300.575 407.198 1.00 70.15  ? 109 TYR H CD1 1 
ATOM 3805 C CD2 . TYR D 2 109 ? 273.910 302.047 406.280 1.00 70.15  ? 109 TYR H CD2 1 
ATOM 3806 C CE1 . TYR D 2 109 ? 271.756 300.370 405.948 1.00 70.15  ? 109 TYR H CE1 1 
ATOM 3807 C CE2 . TYR D 2 109 ? 273.379 301.857 405.024 1.00 70.15  ? 109 TYR H CE2 1 
ATOM 3808 C CZ  . TYR D 2 109 ? 272.303 301.014 404.866 1.00 70.15  ? 109 TYR H CZ  1 
ATOM 3809 O OH  . TYR D 2 109 ? 271.773 300.815 403.617 1.00 70.15  ? 109 TYR H OH  1 
ATOM 3810 N N   . PHE D 2 110 ? 275.004 298.177 409.538 1.00 68.87  ? 110 PHE H N   1 
ATOM 3811 C CA  . PHE D 2 110 ? 274.705 296.930 410.261 1.00 68.87  ? 110 PHE H CA  1 
ATOM 3812 C C   . PHE D 2 110 ? 273.338 296.350 409.884 1.00 68.87  ? 110 PHE H C   1 
ATOM 3813 O O   . PHE D 2 110 ? 272.388 296.362 410.666 1.00 68.87  ? 110 PHE H O   1 
ATOM 3814 C CB  . PHE D 2 110 ? 274.795 297.163 411.770 1.00 68.87  ? 110 PHE H CB  1 
ATOM 3815 C CG  . PHE D 2 110 ? 276.154 297.570 412.235 1.00 68.87  ? 110 PHE H CG  1 
ATOM 3816 C CD1 . PHE D 2 110 ? 277.288 297.200 411.539 1.00 68.87  ? 110 PHE H CD1 1 
ATOM 3817 C CD2 . PHE D 2 110 ? 276.292 298.390 413.333 1.00 68.87  ? 110 PHE H CD2 1 
ATOM 3818 C CE1 . PHE D 2 110 ? 278.527 297.612 411.953 1.00 68.87  ? 110 PHE H CE1 1 
ATOM 3819 C CE2 . PHE D 2 110 ? 277.531 298.798 413.748 1.00 68.87  ? 110 PHE H CE2 1 
ATOM 3820 C CZ  . PHE D 2 110 ? 278.648 298.405 413.063 1.00 68.87  ? 110 PHE H CZ  1 
ATOM 3821 N N   . SER D 2 111 ? 273.259 295.877 408.640 1.00 69.23  ? 111 SER H N   1 
ATOM 3822 C CA  . SER D 2 111 ? 271.991 295.386 408.108 1.00 69.23  ? 111 SER H CA  1 
ATOM 3823 C C   . SER D 2 111 ? 271.550 294.092 408.789 1.00 69.23  ? 111 SER H C   1 
ATOM 3824 O O   . SER D 2 111 ? 270.407 293.985 409.246 1.00 69.23  ? 111 SER H O   1 
ATOM 3825 C CB  . SER D 2 111 ? 272.102 295.197 406.597 1.00 69.23  ? 111 SER H CB  1 
ATOM 3826 O OG  . SER D 2 111 ? 273.048 294.193 406.281 1.00 69.23  ? 111 SER H OG  1 
ATOM 3827 N N   . TYR D 2 112 ? 272.430 293.095 408.864 1.00 70.32  ? 112 TYR H N   1 
ATOM 3828 C CA  . TYR D 2 112 ? 272.103 291.820 409.490 1.00 70.32  ? 112 TYR H CA  1 
ATOM 3829 C C   . TYR D 2 112 ? 272.950 291.597 410.735 1.00 70.32  ? 112 TYR H C   1 
ATOM 3830 O O   . TYR D 2 112 ? 273.980 292.244 410.931 1.00 70.32  ? 112 TYR H O   1 
ATOM 3831 C CB  . TYR D 2 112 ? 272.292 290.646 408.532 1.00 70.32  ? 112 TYR H CB  1 
ATOM 3832 C CG  . TYR D 2 112 ? 271.285 290.618 407.416 1.00 70.32  ? 112 TYR H CG  1 
ATOM 3833 C CD1 . TYR D 2 112 ? 269.992 290.175 407.640 1.00 70.32  ? 112 TYR H CD1 1 
ATOM 3834 C CD2 . TYR D 2 112 ? 271.624 291.027 406.141 1.00 70.32  ? 112 TYR H CD2 1 
ATOM 3835 C CE1 . TYR D 2 112 ? 269.061 290.150 406.623 1.00 70.32  ? 112 TYR H CE1 1 
ATOM 3836 C CE2 . TYR D 2 112 ? 270.699 291.004 405.116 1.00 70.32  ? 112 TYR H CE2 1 
ATOM 3837 C CZ  . TYR D 2 112 ? 269.424 290.562 405.361 1.00 70.32  ? 112 TYR H CZ  1 
ATOM 3838 O OH  . TYR D 2 112 ? 268.508 290.537 404.338 1.00 70.32  ? 112 TYR H OH  1 
ATOM 3839 N N   . TRP D 2 113 ? 272.505 290.657 411.569 1.00 74.05  ? 113 TRP H N   1 
ATOM 3840 C CA  . TRP D 2 113 ? 273.049 290.473 412.910 1.00 74.05  ? 113 TRP H CA  1 
ATOM 3841 C C   . TRP D 2 113 ? 273.196 289.005 413.273 1.00 74.05  ? 113 TRP H C   1 
ATOM 3842 O O   . TRP D 2 113 ? 273.049 288.127 412.419 1.00 74.05  ? 113 TRP H O   1 
ATOM 3843 C CB  . TRP D 2 113 ? 272.146 291.156 413.929 1.00 74.05  ? 113 TRP H CB  1 
ATOM 3844 C CG  . TRP D 2 113 ? 272.213 292.629 413.890 1.00 74.05  ? 113 TRP H CG  1 
ATOM 3845 C CD1 . TRP D 2 113 ? 271.463 293.457 413.122 1.00 74.05  ? 113 TRP H CD1 1 
ATOM 3846 C CD2 . TRP D 2 113 ? 273.043 293.464 414.692 1.00 74.05  ? 113 TRP H CD2 1 
ATOM 3847 N NE1 . TRP D 2 113 ? 271.788 294.761 413.376 1.00 74.05  ? 113 TRP H NE1 1 
ATOM 3848 C CE2 . TRP D 2 113 ? 272.754 294.792 414.345 1.00 74.05  ? 113 TRP H CE2 1 
ATOM 3849 C CE3 . TRP D 2 113 ? 274.005 293.219 415.673 1.00 74.05  ? 113 TRP H CE3 1 
ATOM 3850 C CZ2 . TRP D 2 113 ? 273.394 295.870 414.933 1.00 74.05  ? 113 TRP H CZ2 1 
ATOM 3851 C CZ3 . TRP D 2 113 ? 274.637 294.287 416.254 1.00 74.05  ? 113 TRP H CZ3 1 
ATOM 3852 C CH2 . TRP D 2 113 ? 274.333 295.598 415.883 1.00 74.05  ? 113 TRP H CH2 1 
ATOM 3853 N N   . GLY D 2 114 ? 273.468 288.726 414.547 1.00 79.95  ? 114 GLY H N   1 
ATOM 3854 C CA  . GLY D 2 114 ? 273.615 287.366 415.010 1.00 79.95  ? 114 GLY H CA  1 
ATOM 3855 C C   . GLY D 2 114 ? 273.348 287.255 416.493 1.00 79.95  ? 114 GLY H C   1 
ATOM 3856 O O   . GLY D 2 114 ? 273.161 288.248 417.196 1.00 79.95  ? 114 GLY H O   1 
ATOM 3857 N N   . GLN D 2 115 ? 273.363 286.008 416.977 1.00 82.36  ? 115 GLN H N   1 
ATOM 3858 C CA  . GLN D 2 115 ? 272.945 285.722 418.346 1.00 82.36  ? 115 GLN H CA  1 
ATOM 3859 C C   . GLN D 2 115 ? 273.953 286.236 419.369 1.00 82.36  ? 115 GLN H C   1 
ATOM 3860 O O   . GLN D 2 115 ? 273.576 286.906 420.335 1.00 82.36  ? 115 GLN H O   1 
ATOM 3861 C CB  . GLN D 2 115 ? 272.734 284.220 418.519 1.00 82.36  ? 115 GLN H CB  1 
ATOM 3862 C CG  . GLN D 2 115 ? 271.620 283.649 417.662 1.00 82.36  ? 115 GLN H CG  1 
ATOM 3863 C CD  . GLN D 2 115 ? 270.262 284.204 418.022 1.00 82.36  ? 115 GLN H CD  1 
ATOM 3864 O OE1 . GLN D 2 115 ? 269.685 284.993 417.277 1.00 82.36  ? 115 GLN H OE1 1 
ATOM 3865 N NE2 . GLN D 2 115 ? 269.735 283.786 419.163 1.00 82.36  ? 115 GLN H NE2 1 
ATOM 3866 N N   . GLY D 2 116 ? 275.229 285.927 419.182 1.00 83.20  ? 116 GLY H N   1 
ATOM 3867 C CA  . GLY D 2 116 ? 276.255 286.388 420.091 1.00 83.20  ? 116 GLY H CA  1 
ATOM 3868 C C   . GLY D 2 116 ? 276.639 285.343 421.126 1.00 83.20  ? 116 GLY H C   1 
ATOM 3869 O O   . GLY D 2 116 ? 275.922 284.377 421.378 1.00 83.20  ? 116 GLY H O   1 
ATOM 3870 N N   . THR D 2 117 ? 277.808 285.555 421.732 1.00 86.25  ? 117 THR H N   1 
ATOM 3871 C CA  . THR D 2 117 ? 278.383 284.641 422.710 1.00 86.25  ? 117 THR H CA  1 
ATOM 3872 C C   . THR D 2 117 ? 278.778 285.390 423.974 1.00 86.25  ? 117 THR H C   1 
ATOM 3873 O O   . THR D 2 117 ? 279.590 286.318 423.925 1.00 86.25  ? 117 THR H O   1 
ATOM 3874 C CB  . THR D 2 117 ? 279.619 283.928 422.151 1.00 86.25  ? 117 THR H CB  1 
ATOM 3875 O OG1 . THR D 2 117 ? 280.578 284.905 421.726 1.00 86.25  ? 117 THR H OG1 1 
ATOM 3876 C CG2 . THR D 2 117 ? 279.255 283.032 420.986 1.00 86.25  ? 117 THR H CG2 1 
ATOM 3877 N N   . LEU D 2 118 ? 278.230 284.956 425.108 1.00 88.68  ? 118 LEU H N   1 
ATOM 3878 C CA  . LEU D 2 118 ? 278.515 285.593 426.387 1.00 88.68  ? 118 LEU H CA  1 
ATOM 3879 C C   . LEU D 2 118 ? 279.968 285.390 426.799 1.00 88.68  ? 118 LEU H C   1 
ATOM 3880 O O   . LEU D 2 118 ? 280.477 284.269 426.848 1.00 88.68  ? 118 LEU H O   1 
ATOM 3881 C CB  . LEU D 2 118 ? 277.601 285.038 427.478 1.00 88.68  ? 118 LEU H CB  1 
ATOM 3882 C CG  . LEU D 2 118 ? 276.112 285.360 427.393 1.00 88.68  ? 118 LEU H CG  1 
ATOM 3883 C CD1 . LEU D 2 118 ? 275.342 284.591 428.448 1.00 88.68  ? 118 LEU H CD1 1 
ATOM 3884 C CD2 . LEU D 2 118 ? 275.899 286.850 427.563 1.00 88.68  ? 118 LEU H CD2 1 
ATOM 3885 N N   . VAL D 2 119 ? 280.639 286.501 427.099 1.00 91.11  ? 119 VAL H N   1 
ATOM 3886 C CA  . VAL D 2 119 ? 281.998 286.485 427.619 1.00 91.11  ? 119 VAL H CA  1 
ATOM 3887 C C   . VAL D 2 119 ? 282.007 287.231 428.943 1.00 91.11  ? 119 VAL H C   1 
ATOM 3888 O O   . VAL D 2 119 ? 281.116 288.036 429.229 1.00 91.11  ? 119 VAL H O   1 
ATOM 3889 C CB  . VAL D 2 119 ? 283.013 287.113 426.638 1.00 91.11  ? 119 VAL H CB  1 
ATOM 3890 C CG1 . VAL D 2 119 ? 283.070 286.327 425.347 1.00 91.11  ? 119 VAL H CG1 1 
ATOM 3891 C CG2 . VAL D 2 119 ? 282.646 288.548 426.356 1.00 91.11  ? 119 VAL H CG2 1 
ATOM 3892 N N   . THR D 2 120 ? 283.000 286.930 429.774 1.00 94.94  ? 120 THR H N   1 
ATOM 3893 C CA  . THR D 2 120 ? 283.184 287.623 431.050 1.00 94.94  ? 120 THR H CA  1 
ATOM 3894 C C   . THR D 2 120 ? 284.645 288.016 431.246 1.00 94.94  ? 120 THR H C   1 
ATOM 3895 O O   . THR D 2 120 ? 285.218 287.792 432.310 1.00 94.94  ? 120 THR H O   1 
ATOM 3896 C CB  . THR D 2 120 ? 282.741 286.764 432.251 1.00 94.94  ? 120 THR H CB  1 
ATOM 3897 O OG1 . THR D 2 120 ? 283.448 285.521 432.232 1.00 94.94  ? 120 THR H OG1 1 
ATOM 3898 C CG2 . THR D 2 120 ? 281.234 286.514 432.249 1.00 94.94  ? 120 THR H CG2 1 
ATOM 3899 N N   . ASN E 3 4   ? 284.031 311.918 419.654 1.00 93.37  ? 4   ASN L N   1 
ATOM 3900 C CA  . ASN E 3 4   ? 282.813 311.118 419.635 1.00 93.37  ? 4   ASN L CA  1 
ATOM 3901 C C   . ASN E 3 4   ? 281.587 312.003 419.461 1.00 93.37  ? 4   ASN L C   1 
ATOM 3902 O O   . ASN E 3 4   ? 281.476 313.053 420.090 1.00 93.37  ? 4   ASN L O   1 
ATOM 3903 C CB  . ASN E 3 4   ? 282.685 310.295 420.920 1.00 93.37  ? 4   ASN L CB  1 
ATOM 3904 C CG  . ASN E 3 4   ? 283.782 309.262 421.063 1.00 93.37  ? 4   ASN L CG  1 
ATOM 3905 O OD1 . ASN E 3 4   ? 284.611 309.340 421.968 1.00 93.37  ? 4   ASN L OD1 1 
ATOM 3906 N ND2 . ASN E 3 4   ? 283.793 308.284 420.169 1.00 93.37  ? 4   ASN L ND2 1 
ATOM 3907 N N   . ILE E 3 5   ? 280.667 311.579 418.598 1.00 90.34  ? 5   ILE L N   1 
ATOM 3908 C CA  . ILE E 3 5   ? 279.401 312.276 418.414 1.00 90.34  ? 5   ILE L CA  1 
ATOM 3909 C C   . ILE E 3 5   ? 278.382 311.569 419.300 1.00 90.34  ? 5   ILE L C   1 
ATOM 3910 O O   . ILE E 3 5   ? 277.829 310.533 418.934 1.00 90.34  ? 5   ILE L O   1 
ATOM 3911 C CB  . ILE E 3 5   ? 278.978 312.312 416.945 1.00 90.34  ? 5   ILE L CB  1 
ATOM 3912 C CG1 . ILE E 3 5   ? 280.010 313.094 416.143 1.00 90.34  ? 5   ILE L CG1 1 
ATOM 3913 C CG2 . ILE E 3 5   ? 277.628 312.980 416.782 1.00 90.34  ? 5   ILE L CG2 1 
ATOM 3914 C CD1 . ILE E 3 5   ? 279.816 313.030 414.662 1.00 90.34  ? 5   ILE L CD1 1 
ATOM 3915 N N   . VAL E 3 6   ? 278.144 312.131 420.478 1.00 93.29  ? 6   VAL L N   1 
ATOM 3916 C CA  . VAL E 3 6   ? 277.297 311.494 421.477 1.00 93.29  ? 6   VAL L CA  1 
ATOM 3917 C C   . VAL E 3 6   ? 275.837 311.697 421.104 1.00 93.29  ? 6   VAL L C   1 
ATOM 3918 O O   . VAL E 3 6   ? 275.375 312.833 420.946 1.00 93.29  ? 6   VAL L O   1 
ATOM 3919 C CB  . VAL E 3 6   ? 277.593 312.059 422.874 1.00 93.29  ? 6   VAL L CB  1 
ATOM 3920 C CG1 . VAL E 3 6   ? 276.658 311.455 423.898 1.00 93.29  ? 6   VAL L CG1 1 
ATOM 3921 C CG2 . VAL E 3 6   ? 279.037 311.799 423.251 1.00 93.29  ? 6   VAL L CG2 1 
ATOM 3922 N N   . LEU E 3 7   ? 275.109 310.597 420.960 1.00 93.54  ? 7   LEU L N   1 
ATOM 3923 C CA  . LEU E 3 7   ? 273.674 310.634 420.729 1.00 93.54  ? 7   LEU L CA  1 
ATOM 3924 C C   . LEU E 3 7   ? 272.962 310.487 422.064 1.00 93.54  ? 7   LEU L C   1 
ATOM 3925 O O   . LEU E 3 7   ? 273.188 309.513 422.788 1.00 93.54  ? 7   LEU L O   1 
ATOM 3926 C CB  . LEU E 3 7   ? 273.241 309.522 419.777 1.00 93.54  ? 7   LEU L CB  1 
ATOM 3927 C CG  . LEU E 3 7   ? 273.788 309.582 418.355 1.00 93.54  ? 7   LEU L CG  1 
ATOM 3928 C CD1 . LEU E 3 7   ? 273.341 308.366 417.602 1.00 93.54  ? 7   LEU L CD1 1 
ATOM 3929 C CD2 . LEU E 3 7   ? 273.316 310.827 417.652 1.00 93.54  ? 7   LEU L CD2 1 
ATOM 3930 N N   . THR E 3 8   ? 272.107 311.452 422.387 1.00 97.66  ? 8   THR L N   1 
ATOM 3931 C CA  . THR E 3 8   ? 271.415 311.486 423.667 1.00 97.66  ? 8   THR L CA  1 
ATOM 3932 C C   . THR E 3 8   ? 269.926 311.303 423.429 1.00 97.66  ? 8   THR L C   1 
ATOM 3933 O O   . THR E 3 8   ? 269.292 312.136 422.774 1.00 97.66  ? 8   THR L O   1 
ATOM 3934 C CB  . THR E 3 8   ? 271.684 312.800 424.401 1.00 97.66  ? 8   THR L CB  1 
ATOM 3935 O OG1 . THR E 3 8   ? 271.188 313.892 423.622 1.00 97.66  ? 8   THR L OG1 1 
ATOM 3936 C CG2 . THR E 3 8   ? 273.177 312.987 424.626 1.00 97.66  ? 8   THR L CG2 1 
ATOM 3937 N N   . GLN E 3 9   ? 269.377 310.208 423.946 1.00 101.58 ? 9   GLN L N   1 
ATOM 3938 C CA  . GLN E 3 9   ? 267.938 309.994 423.906 1.00 101.58 ? 9   GLN L CA  1 
ATOM 3939 C C   . GLN E 3 9   ? 267.234 310.985 424.822 1.00 101.58 ? 9   GLN L C   1 
ATOM 3940 O O   . GLN E 3 9   ? 267.618 311.162 425.981 1.00 101.58 ? 9   GLN L O   1 
ATOM 3941 C CB  . GLN E 3 9   ? 267.603 308.571 424.342 1.00 101.58 ? 9   GLN L CB  1 
ATOM 3942 C CG  . GLN E 3 9   ? 268.169 307.478 423.464 1.00 101.58 ? 9   GLN L CG  1 
ATOM 3943 C CD  . GLN E 3 9   ? 267.543 307.445 422.094 1.00 101.58 ? 9   GLN L CD  1 
ATOM 3944 O OE1 . GLN E 3 9   ? 266.359 307.734 421.933 1.00 101.58 ? 9   GLN L OE1 1 
ATOM 3945 N NE2 . GLN E 3 9   ? 268.327 307.061 421.097 1.00 101.58 ? 9   GLN L NE2 1 
ATOM 3946 N N   . SER E 3 10  ? 266.197 311.636 424.302 1.00 104.99 ? 10  SER L N   1 
ATOM 3947 C CA  . SER E 3 10  ? 265.484 312.609 425.123 1.00 104.99 ? 10  SER L CA  1 
ATOM 3948 C C   . SER E 3 10  ? 264.560 311.949 426.153 1.00 104.99 ? 10  SER L C   1 
ATOM 3949 O O   . SER E 3 10  ? 264.483 312.459 427.278 1.00 104.99 ? 10  SER L O   1 
ATOM 3950 C CB  . SER E 3 10  ? 264.723 313.613 424.247 1.00 104.99 ? 10  SER L CB  1 
ATOM 3951 O OG  . SER E 3 10  ? 263.992 314.530 425.044 1.00 104.99 ? 10  SER L OG  1 
ATOM 3952 N N   . PRO E 3 11  ? 263.849 310.849 425.866 1.00 105.03 ? 11  PRO L N   1 
ATOM 3953 C CA  . PRO E 3 11  ? 263.307 310.071 426.984 1.00 105.03 ? 11  PRO L CA  1 
ATOM 3954 C C   . PRO E 3 11  ? 264.253 308.957 427.397 1.00 105.03 ? 11  PRO L C   1 
ATOM 3955 O O   . PRO E 3 11  ? 265.188 308.595 426.682 1.00 105.03 ? 11  PRO L O   1 
ATOM 3956 C CB  . PRO E 3 11  ? 262.006 309.493 426.412 1.00 105.03 ? 11  PRO L CB  1 
ATOM 3957 C CG  . PRO E 3 11  ? 262.306 309.298 425.006 1.00 105.03 ? 11  PRO L CG  1 
ATOM 3958 C CD  . PRO E 3 11  ? 263.195 310.435 424.603 1.00 105.03 ? 11  PRO L CD  1 
ATOM 3959 N N   . ALA E 3 12  ? 264.002 308.422 428.589 1.00 105.32 ? 12  ALA L N   1 
ATOM 3960 C CA  . ALA E 3 12  ? 264.681 307.211 429.030 1.00 105.32 ? 12  ALA L CA  1 
ATOM 3961 C C   . ALA E 3 12  ? 263.755 306.004 428.964 1.00 105.32 ? 12  ALA L C   1 
ATOM 3962 O O   . ALA E 3 12  ? 264.211 304.877 428.745 1.00 105.32 ? 12  ALA L O   1 
ATOM 3963 C CB  . ALA E 3 12  ? 265.220 307.390 430.451 1.00 105.32 ? 12  ALA L CB  1 
ATOM 3964 N N   . SER E 3 13  ? 262.459 306.235 429.149 1.00 106.60 ? 13  SER L N   1 
ATOM 3965 C CA  . SER E 3 13  ? 261.444 305.201 429.051 1.00 106.60 ? 13  SER L CA  1 
ATOM 3966 C C   . SER E 3 13  ? 260.126 305.875 428.709 1.00 106.60 ? 13  SER L C   1 
ATOM 3967 O O   . SER E 3 13  ? 259.922 307.056 428.995 1.00 106.60 ? 13  SER L O   1 
ATOM 3968 C CB  . SER E 3 13  ? 261.326 304.397 430.350 1.00 106.60 ? 13  SER L CB  1 
ATOM 3969 O OG  . SER E 3 13  ? 260.866 305.213 431.411 1.00 106.60 ? 13  SER L OG  1 
ATOM 3970 N N   . LEU E 3 14  ? 259.232 305.113 428.086 1.00 107.34 ? 14  LEU L N   1 
ATOM 3971 C CA  . LEU E 3 14  ? 257.973 305.673 427.623 1.00 107.34 ? 14  LEU L CA  1 
ATOM 3972 C C   . LEU E 3 14  ? 256.923 304.572 427.639 1.00 107.34 ? 14  LEU L C   1 
ATOM 3973 O O   . LEU E 3 14  ? 257.245 303.385 427.575 1.00 107.34 ? 14  LEU L O   1 
ATOM 3974 C CB  . LEU E 3 14  ? 258.145 306.298 426.230 1.00 107.34 ? 14  LEU L CB  1 
ATOM 3975 C CG  . LEU E 3 14  ? 257.065 307.162 425.578 1.00 107.34 ? 14  LEU L CG  1 
ATOM 3976 C CD1 . LEU E 3 14  ? 257.723 308.255 424.765 1.00 107.34 ? 14  LEU L CD1 1 
ATOM 3977 C CD2 . LEU E 3 14  ? 256.175 306.328 424.677 1.00 107.34 ? 14  LEU L CD2 1 
ATOM 3978 N N   . ALA E 3 15  ? 255.660 304.976 427.752 1.00 109.91 ? 15  ALA L N   1 
ATOM 3979 C CA  . ALA E 3 15  ? 254.562 304.021 427.773 1.00 109.91 ? 15  ALA L CA  1 
ATOM 3980 C C   . ALA E 3 15  ? 253.342 304.637 427.109 1.00 109.91 ? 15  ALA L C   1 
ATOM 3981 O O   . ALA E 3 15  ? 252.972 305.771 427.423 1.00 109.91 ? 15  ALA L O   1 
ATOM 3982 C CB  . ALA E 3 15  ? 254.229 303.595 429.207 1.00 109.91 ? 15  ALA L CB  1 
ATOM 3983 N N   . VAL E 3 16  ? 252.730 303.891 426.188 1.00 111.62 ? 16  VAL L N   1 
ATOM 3984 C CA  . VAL E 3 16  ? 251.483 304.283 425.544 1.00 111.62 ? 16  VAL L CA  1 
ATOM 3985 C C   . VAL E 3 16  ? 250.512 303.114 425.613 1.00 111.62 ? 16  VAL L C   1 
ATOM 3986 O O   . VAL E 3 16  ? 250.824 302.042 426.132 1.00 111.62 ? 16  VAL L O   1 
ATOM 3987 C CB  . VAL E 3 16  ? 251.671 304.721 424.075 1.00 111.62 ? 16  VAL L CB  1 
ATOM 3988 C CG1 . VAL E 3 16  ? 252.508 305.984 423.980 1.00 111.62 ? 16  VAL L CG1 1 
ATOM 3989 C CG2 . VAL E 3 16  ? 252.293 303.595 423.265 1.00 111.62 ? 16  VAL L CG2 1 
ATOM 3990 N N   . SER E 3 17  ? 249.319 303.340 425.073 1.00 111.96 ? 17  SER L N   1 
ATOM 3991 C CA  . SER E 3 17  ? 248.314 302.301 424.930 1.00 111.96 ? 17  SER L CA  1 
ATOM 3992 C C   . SER E 3 17  ? 248.403 301.721 423.521 1.00 111.96 ? 17  SER L C   1 
ATOM 3993 O O   . SER E 3 17  ? 249.316 302.037 422.756 1.00 111.96 ? 17  SER L O   1 
ATOM 3994 C CB  . SER E 3 17  ? 246.929 302.866 425.236 1.00 111.96 ? 17  SER L CB  1 
ATOM 3995 O OG  . SER E 3 17  ? 246.562 303.844 424.281 1.00 111.96 ? 17  SER L OG  1 
ATOM 3996 N N   . LEU E 3 18  ? 247.446 300.867 423.152 1.00 111.35 ? 18  LEU L N   1 
ATOM 3997 C CA  . LEU E 3 18  ? 247.455 300.274 421.819 1.00 111.35 ? 18  LEU L CA  1 
ATOM 3998 C C   . LEU E 3 18  ? 246.868 301.195 420.757 1.00 111.35 ? 18  LEU L C   1 
ATOM 3999 O O   . LEU E 3 18  ? 246.817 300.810 419.584 1.00 111.35 ? 18  LEU L O   1 
ATOM 4000 C CB  . LEU E 3 18  ? 246.689 298.951 421.819 1.00 111.35 ? 18  LEU L CB  1 
ATOM 4001 C CG  . LEU E 3 18  ? 247.329 297.778 422.556 1.00 111.35 ? 18  LEU L CG  1 
ATOM 4002 C CD1 . LEU E 3 18  ? 246.390 296.586 422.586 1.00 111.35 ? 18  LEU L CD1 1 
ATOM 4003 C CD2 . LEU E 3 18  ? 248.630 297.406 421.879 1.00 111.35 ? 18  LEU L CD2 1 
ATOM 4004 N N   . GLY E 3 19  ? 246.411 302.384 421.131 1.00 111.95 ? 19  GLY L N   1 
ATOM 4005 C CA  . GLY E 3 19  ? 245.790 303.266 420.165 1.00 111.95 ? 19  GLY L CA  1 
ATOM 4006 C C   . GLY E 3 19  ? 246.593 304.507 419.841 1.00 111.95 ? 19  GLY L C   1 
ATOM 4007 O O   . GLY E 3 19  ? 246.558 304.996 418.708 1.00 111.95 ? 19  GLY L O   1 
ATOM 4008 N N   . GLN E 3 20  ? 247.310 305.032 420.827 1.00 112.53 ? 20  GLN L N   1 
ATOM 4009 C CA  . GLN E 3 20  ? 247.965 306.320 420.671 1.00 112.53 ? 20  GLN L CA  1 
ATOM 4010 C C   . GLN E 3 20  ? 249.239 306.199 419.847 1.00 112.53 ? 20  GLN L C   1 
ATOM 4011 O O   . GLN E 3 20  ? 249.785 305.109 419.656 1.00 112.53 ? 20  GLN L O   1 
ATOM 4012 C CB  . GLN E 3 20  ? 248.285 306.924 422.037 1.00 112.53 ? 20  GLN L CB  1 
ATOM 4013 C CG  . GLN E 3 20  ? 247.058 307.325 422.831 1.00 112.53 ? 20  GLN L CG  1 
ATOM 4014 C CD  . GLN E 3 20  ? 247.409 307.942 424.165 1.00 112.53 ? 20  GLN L CD  1 
ATOM 4015 O OE1 . GLN E 3 20  ? 248.578 308.003 424.544 1.00 112.53 ? 20  GLN L OE1 1 
ATOM 4016 N NE2 . GLN E 3 20  ? 246.397 308.412 424.886 1.00 112.53 ? 20  GLN L NE2 1 
ATOM 4017 N N   . ARG E 3 21  ? 249.700 307.340 419.344 1.00 110.61 ? 21  ARG L N   1 
ATOM 4018 C CA  . ARG E 3 21  ? 250.968 307.397 418.640 1.00 110.61 ? 21  ARG L CA  1 
ATOM 4019 C C   . ARG E 3 21  ? 252.121 307.385 419.641 1.00 110.61 ? 21  ARG L C   1 
ATOM 4020 O O   . ARG E 3 21  ? 251.938 307.577 420.846 1.00 110.61 ? 21  ARG L O   1 
ATOM 4021 C CB  . ARG E 3 21  ? 251.038 308.645 417.764 1.00 110.61 ? 21  ARG L CB  1 
ATOM 4022 C CG  . ARG E 3 21  ? 251.058 309.944 418.552 1.00 110.61 ? 21  ARG L CG  1 
ATOM 4023 C CD  . ARG E 3 21  ? 250.996 311.146 417.629 1.00 110.61 ? 21  ARG L CD  1 
ATOM 4024 N NE  . ARG E 3 21  ? 252.186 311.265 416.796 1.00 110.61 ? 21  ARG L NE  1 
ATOM 4025 C CZ  . ARG E 3 21  ? 252.253 312.013 415.701 1.00 110.61 ? 21  ARG L CZ  1 
ATOM 4026 N NH1 . ARG E 3 21  ? 251.195 312.707 415.305 1.00 110.61 ? 21  ARG L NH1 1 
ATOM 4027 N NH2 . ARG E 3 21  ? 253.376 312.067 414.998 1.00 110.61 ? 21  ARG L NH2 1 
ATOM 4028 N N   . ALA E 3 22  ? 253.326 307.159 419.129 1.00 107.44 ? 22  ALA L N   1 
ATOM 4029 C CA  . ALA E 3 22  ? 254.508 307.078 419.973 1.00 107.44 ? 22  ALA L CA  1 
ATOM 4030 C C   . ALA E 3 22  ? 255.664 307.797 419.300 1.00 107.44 ? 22  ALA L C   1 
ATOM 4031 O O   . ALA E 3 22  ? 255.999 307.509 418.149 1.00 107.44 ? 22  ALA L O   1 
ATOM 4032 C CB  . ALA E 3 22  ? 254.887 305.621 420.262 1.00 107.44 ? 22  ALA L CB  1 
ATOM 4033 N N   . THR E 3 23  ? 256.271 308.733 420.023 1.00 105.17 ? 23  THR L N   1 
ATOM 4034 C CA  . THR E 3 23  ? 257.398 309.501 419.520 1.00 105.17 ? 23  THR L CA  1 
ATOM 4035 C C   . THR E 3 23  ? 258.638 309.216 420.352 1.00 105.17 ? 23  THR L C   1 
ATOM 4036 O O   . THR E 3 23  ? 258.546 308.872 421.534 1.00 105.17 ? 23  THR L O   1 
ATOM 4037 C CB  . THR E 3 23  ? 257.112 311.003 419.533 1.00 105.17 ? 23  THR L CB  1 
ATOM 4038 O OG1 . THR E 3 23  ? 256.871 311.433 420.877 1.00 105.17 ? 23  THR L OG1 1 
ATOM 4039 C CG2 . THR E 3 23  ? 255.900 311.322 418.671 1.00 105.17 ? 23  THR L CG2 1 
ATOM 4040 N N   . ILE E 3 24  ? 259.792 309.362 419.714 1.00 100.24 ? 24  ILE L N   1 
ATOM 4041 C CA  . ILE E 3 24  ? 261.097 309.178 420.333 1.00 100.24 ? 24  ILE L CA  1 
ATOM 4042 C C   . ILE E 3 24  ? 262.106 309.983 419.526 1.00 100.24 ? 24  ILE L C   1 
ATOM 4043 O O   . ILE E 3 24  ? 262.086 309.958 418.293 1.00 100.24 ? 24  ILE L O   1 
ATOM 4044 C CB  . ILE E 3 24  ? 261.473 307.679 420.414 1.00 100.24 ? 24  ILE L CB  1 
ATOM 4045 C CG1 . ILE E 3 24  ? 262.902 307.491 420.921 1.00 100.24 ? 24  ILE L CG1 1 
ATOM 4046 C CG2 . ILE E 3 24  ? 261.196 306.946 419.111 1.00 100.24 ? 24  ILE L CG2 1 
ATOM 4047 C CD1 . ILE E 3 24  ? 263.277 306.067 421.097 1.00 100.24 ? 24  ILE L CD1 1 
ATOM 4048 N N   . SER E 3 25  ? 262.966 310.729 420.213 1.00 100.01 ? 25  SER L N   1 
ATOM 4049 C CA  . SER E 3 25  ? 263.908 311.594 419.523 1.00 100.01 ? 25  SER L CA  1 
ATOM 4050 C C   . SER E 3 25  ? 265.328 311.300 419.981 1.00 100.01 ? 25  SER L C   1 
ATOM 4051 O O   . SER E 3 25  ? 265.576 310.957 421.139 1.00 100.01 ? 25  SER L O   1 
ATOM 4052 C CB  . SER E 3 25  ? 263.583 313.077 419.745 1.00 100.01 ? 25  SER L CB  1 
ATOM 4053 O OG  . SER E 3 25  ? 263.779 313.447 421.095 1.00 100.01 ? 25  SER L OG  1 
ATOM 4054 N N   . CYS E 3 26  ? 266.261 311.431 419.040 1.00 98.68  ? 26  CYS L N   1 
ATOM 4055 C CA  . CYS E 3 26  ? 267.688 311.418 419.321 1.00 98.68  ? 26  CYS L CA  1 
ATOM 4056 C C   . CYS E 3 26  ? 268.241 312.809 419.067 1.00 98.68  ? 26  CYS L C   1 
ATOM 4057 O O   . CYS E 3 26  ? 267.769 313.522 418.178 1.00 98.68  ? 26  CYS L O   1 
ATOM 4058 C CB  . CYS E 3 26  ? 268.437 310.390 418.460 1.00 98.68  ? 26  CYS L CB  1 
ATOM 4059 S SG  . CYS E 3 26  ? 268.059 308.669 418.855 1.00 98.68  ? 26  CYS L SG  1 
ATOM 4060 N N   . ARG E 3 27  ? 269.232 313.200 419.859 1.00 97.74  ? 27  ARG L N   1 
ATOM 4061 C CA  . ARG E 3 27  ? 269.864 314.506 419.738 1.00 97.74  ? 27  ARG L CA  1 
ATOM 4062 C C   . ARG E 3 27  ? 271.341 314.300 419.456 1.00 97.74  ? 27  ARG L C   1 
ATOM 4063 O O   . ARG E 3 27  ? 272.058 313.718 420.276 1.00 97.74  ? 27  ARG L O   1 
ATOM 4064 C CB  . ARG E 3 27  ? 269.663 315.337 421.005 1.00 97.74  ? 27  ARG L CB  1 
ATOM 4065 C CG  . ARG E 3 27  ? 268.216 315.665 421.300 1.00 97.74  ? 27  ARG L CG  1 
ATOM 4066 C CD  . ARG E 3 27  ? 267.649 316.588 420.243 1.00 97.74  ? 27  ARG L CD  1 
ATOM 4067 N NE  . ARG E 3 27  ? 268.391 317.841 420.156 1.00 97.74  ? 27  ARG L NE  1 
ATOM 4068 C CZ  . ARG E 3 27  ? 268.141 318.908 420.906 1.00 97.74  ? 27  ARG L CZ  1 
ATOM 4069 N NH1 . ARG E 3 27  ? 268.867 320.008 420.762 1.00 97.74  ? 27  ARG L NH1 1 
ATOM 4070 N NH2 . ARG E 3 27  ? 267.162 318.877 421.797 1.00 97.74  ? 27  ARG L NH2 1 
ATOM 4071 N N   . ALA E 3 28  ? 271.793 314.778 418.304 1.00 92.86  ? 28  ALA L N   1 
ATOM 4072 C CA  . ALA E 3 28  ? 273.170 314.570 417.889 1.00 92.86  ? 28  ALA L CA  1 
ATOM 4073 C C   . ALA E 3 28  ? 274.079 315.640 418.469 1.00 92.86  ? 28  ALA L C   1 
ATOM 4074 O O   . ALA E 3 28  ? 273.672 316.790 418.652 1.00 92.86  ? 28  ALA L O   1 
ATOM 4075 C CB  . ALA E 3 28  ? 273.271 314.569 416.367 1.00 92.86  ? 28  ALA L CB  1 
ATOM 4076 N N   . SER E 3 29  ? 275.321 315.251 418.759 1.00 93.00  ? 29  SER L N   1 
ATOM 4077 C CA  . SER E 3 29  ? 276.299 316.208 419.264 1.00 93.00  ? 29  SER L CA  1 
ATOM 4078 C C   . SER E 3 29  ? 276.733 317.178 418.178 1.00 93.00  ? 29  SER L C   1 
ATOM 4079 O O   . SER E 3 29  ? 276.881 318.379 418.430 1.00 93.00  ? 29  SER L O   1 
ATOM 4080 C CB  . SER E 3 29  ? 277.511 315.473 419.828 1.00 93.00  ? 29  SER L CB  1 
ATOM 4081 O OG  . SER E 3 29  ? 278.513 316.395 420.218 1.00 93.00  ? 29  SER L OG  1 
ATOM 4082 N N   . GLU E 3 30  ? 276.944 316.677 416.963 1.00 91.88  ? 30  GLU L N   1 
ATOM 4083 C CA  . GLU E 3 30  ? 277.371 317.518 415.855 1.00 91.88  ? 30  GLU L CA  1 
ATOM 4084 C C   . GLU E 3 30  ? 276.368 317.425 414.716 1.00 91.88  ? 30  GLU L C   1 
ATOM 4085 O O   . GLU E 3 30  ? 275.313 316.802 414.861 1.00 91.88  ? 30  GLU L O   1 
ATOM 4086 C CB  . GLU E 3 30  ? 278.760 317.104 415.371 1.00 91.88  ? 30  GLU L CB  1 
ATOM 4087 C CG  . GLU E 3 30  ? 279.853 317.275 416.405 1.00 91.88  ? 30  GLU L CG  1 
ATOM 4088 C CD  . GLU E 3 30  ? 281.214 316.876 415.878 1.00 91.88  ? 30  GLU L CD  1 
ATOM 4089 O OE1 . GLU E 3 30  ? 281.288 316.400 414.727 1.00 91.88  ? 30  GLU L OE1 1 
ATOM 4090 O OE2 . GLU E 3 30  ? 282.208 317.032 416.616 1.00 91.88  ? 30  GLU L OE2 1 
ATOM 4091 N N   . SER E 3 31  ? 276.682 318.043 413.584 1.00 87.79  ? 31  SER L N   1 
ATOM 4092 C CA  . SER E 3 31  ? 275.864 317.880 412.394 1.00 87.79  ? 31  SER L CA  1 
ATOM 4093 C C   . SER E 3 31  ? 276.120 316.512 411.782 1.00 87.79  ? 31  SER L C   1 
ATOM 4094 O O   . SER E 3 31  ? 277.265 316.065 411.683 1.00 87.79  ? 31  SER L O   1 
ATOM 4095 C CB  . SER E 3 31  ? 276.169 318.973 411.373 1.00 87.79  ? 31  SER L CB  1 
ATOM 4096 O OG  . SER E 3 31  ? 277.483 318.833 410.865 1.00 87.79  ? 31  SER L OG  1 
ATOM 4097 N N   . VAL E 3 32  ? 275.044 315.841 411.385 1.00 82.74  ? 32  VAL L N   1 
ATOM 4098 C CA  . VAL E 3 32  ? 275.146 314.525 410.782 1.00 82.74  ? 32  VAL L CA  1 
ATOM 4099 C C   . VAL E 3 32  ? 274.861 314.555 409.281 1.00 82.74  ? 32  VAL L C   1 
ATOM 4100 O O   . VAL E 3 32  ? 275.510 313.819 408.526 1.00 82.74  ? 32  VAL L O   1 
ATOM 4101 C CB  . VAL E 3 32  ? 274.209 313.539 411.513 1.00 82.74  ? 32  VAL L CB  1 
ATOM 4102 C CG1 . VAL E 3 32  ? 274.342 312.137 410.979 1.00 82.74  ? 32  VAL L CG1 1 
ATOM 4103 C CG2 . VAL E 3 32  ? 274.510 313.543 412.990 1.00 82.74  ? 32  VAL L CG2 1 
ATOM 4104 N N   . ASP E 3 33  ? 273.959 315.427 408.823 1.00 80.50  ? 33  ASP L N   1 
ATOM 4105 C CA  . ASP E 3 33  ? 273.665 315.623 407.406 1.00 80.50  ? 33  ASP L CA  1 
ATOM 4106 C C   . ASP E 3 33  ? 274.892 316.097 406.641 1.00 80.50  ? 33  ASP L C   1 
ATOM 4107 O O   . ASP E 3 33  ? 275.341 317.232 406.812 1.00 80.50  ? 33  ASP L O   1 
ATOM 4108 C CB  . ASP E 3 33  ? 272.525 316.629 407.242 1.00 80.50  ? 33  ASP L CB  1 
ATOM 4109 C CG  . ASP E 3 33  ? 272.140 316.851 405.797 1.00 80.50  ? 33  ASP L CG  1 
ATOM 4110 O OD1 . ASP E 3 33  ? 271.503 315.960 405.204 1.00 80.50  ? 33  ASP L OD1 1 
ATOM 4111 O OD2 . ASP E 3 33  ? 272.465 317.927 405.255 1.00 80.50  ? 33  ASP L OD2 1 
ATOM 4112 N N   . HIS E 3 34  ? 275.433 315.231 405.786 1.00 75.01  ? 34  HIS L N   1 
ATOM 4113 C CA  . HIS E 3 34  ? 276.752 315.439 405.205 1.00 75.01  ? 34  HIS L CA  1 
ATOM 4114 C C   . HIS E 3 34  ? 276.683 316.253 403.918 1.00 75.01  ? 34  HIS L C   1 
ATOM 4115 O O   . HIS E 3 34  ? 277.251 317.346 403.846 1.00 75.01  ? 34  HIS L O   1 
ATOM 4116 C CB  . HIS E 3 34  ? 277.417 314.083 404.951 1.00 75.01  ? 34  HIS L CB  1 
ATOM 4117 C CG  . HIS E 3 34  ? 278.885 314.165 404.686 1.00 75.01  ? 34  HIS L CG  1 
ATOM 4118 N ND1 . HIS E 3 34  ? 279.814 314.305 405.693 1.00 75.01  ? 34  HIS L ND1 1 
ATOM 4119 C CD2 . HIS E 3 34  ? 279.588 314.132 403.530 1.00 75.01  ? 34  HIS L CD2 1 
ATOM 4120 C CE1 . HIS E 3 34  ? 281.026 314.345 405.171 1.00 75.01  ? 34  HIS L CE1 1 
ATOM 4121 N NE2 . HIS E 3 34  ? 280.916 314.242 403.859 1.00 75.01  ? 34  HIS L NE2 1 
ATOM 4122 N N   . SER E 3 35  ? 275.995 315.745 402.895 1.00 73.78  ? 35  SER L N   1 
ATOM 4123 C CA  . SER E 3 35  ? 275.818 316.505 401.662 1.00 73.78  ? 35  SER L CA  1 
ATOM 4124 C C   . SER E 3 35  ? 274.358 316.857 401.415 1.00 73.78  ? 35  SER L C   1 
ATOM 4125 O O   . SER E 3 35  ? 274.024 318.040 401.313 1.00 73.78  ? 35  SER L O   1 
ATOM 4126 C CB  . SER E 3 35  ? 276.389 315.723 400.476 1.00 73.78  ? 35  SER L CB  1 
ATOM 4127 O OG  . SER E 3 35  ? 275.616 314.569 400.218 1.00 73.78  ? 35  SER L OG  1 
ATOM 4128 N N   . GLY E 3 36  ? 273.477 315.869 401.321 1.00 74.17  ? 36  GLY L N   1 
ATOM 4129 C CA  . GLY E 3 36  ? 272.057 316.133 401.234 1.00 74.17  ? 36  GLY L CA  1 
ATOM 4130 C C   . GLY E 3 36  ? 271.291 315.120 402.049 1.00 74.17  ? 36  GLY L C   1 
ATOM 4131 O O   . GLY E 3 36  ? 270.069 315.205 402.199 1.00 74.17  ? 36  GLY L O   1 
ATOM 4132 N N   . ASN E 3 37  ? 272.027 314.156 402.591 1.00 75.58  ? 37  ASN L N   1 
ATOM 4133 C CA  . ASN E 3 37  ? 271.478 313.005 403.285 1.00 75.58  ? 37  ASN L CA  1 
ATOM 4134 C C   . ASN E 3 37  ? 272.101 312.879 404.666 1.00 75.58  ? 37  ASN L C   1 
ATOM 4135 O O   . ASN E 3 37  ? 273.298 313.120 404.846 1.00 75.58  ? 37  ASN L O   1 
ATOM 4136 C CB  . ASN E 3 37  ? 271.696 311.733 402.461 1.00 75.58  ? 37  ASN L CB  1 
ATOM 4137 C CG  . ASN E 3 37  ? 273.101 311.634 401.907 1.00 75.58  ? 37  ASN L CG  1 
ATOM 4138 O OD1 . ASN E 3 37  ? 273.941 312.496 402.149 1.00 75.58  ? 37  ASN L OD1 1 
ATOM 4139 N ND2 . ASN E 3 37  ? 273.360 310.584 401.150 1.00 75.58  ? 37  ASN L ND2 1 
ATOM 4140 N N   . ASN E 3 38  ? 271.278 312.513 405.639 1.00 79.28  ? 38  ASN L N   1 
ATOM 4141 C CA  . ASN E 3 38  ? 271.674 312.459 407.037 1.00 79.28  ? 38  ASN L CA  1 
ATOM 4142 C C   . ASN E 3 38  ? 271.808 311.022 407.522 1.00 79.28  ? 38  ASN L C   1 
ATOM 4143 O O   . ASN E 3 38  ? 270.943 310.181 407.269 1.00 79.28  ? 38  ASN L O   1 
ATOM 4144 C CB  . ASN E 3 38  ? 270.676 313.247 407.882 1.00 79.28  ? 38  ASN L CB  1 
ATOM 4145 C CG  . ASN E 3 38  ? 269.242 312.985 407.484 1.00 79.28  ? 38  ASN L CG  1 
ATOM 4146 O OD1 . ASN E 3 38  ? 268.958 312.116 406.664 1.00 79.28  ? 38  ASN L OD1 1 
ATOM 4147 N ND2 . ASN E 3 38  ? 268.331 313.778 408.023 1.00 79.28  ? 38  ASN L ND2 1 
ATOM 4148 N N   . PHE E 3 39  ? 272.910 310.743 408.209 1.00 75.31  ? 39  PHE L N   1 
ATOM 4149 C CA  . PHE E 3 39  ? 273.307 309.373 408.515 1.00 75.31  ? 39  PHE L CA  1 
ATOM 4150 C C   . PHE E 3 39  ? 272.932 309.002 409.951 1.00 75.31  ? 39  PHE L C   1 
ATOM 4151 O O   . PHE E 3 39  ? 273.773 308.876 410.836 1.00 75.31  ? 39  PHE L O   1 
ATOM 4152 C CB  . PHE E 3 39  ? 274.798 309.208 408.274 1.00 75.31  ? 39  PHE L CB  1 
ATOM 4153 C CG  . PHE E 3 39  ? 275.203 309.402 406.849 1.00 75.31  ? 39  PHE L CG  1 
ATOM 4154 C CD1 . PHE E 3 39  ? 275.042 308.389 405.927 1.00 75.31  ? 39  PHE L CD1 1 
ATOM 4155 C CD2 . PHE E 3 39  ? 275.746 310.595 406.432 1.00 75.31  ? 39  PHE L CD2 1 
ATOM 4156 C CE1 . PHE E 3 39  ? 275.414 308.567 404.616 1.00 75.31  ? 39  PHE L CE1 1 
ATOM 4157 C CE2 . PHE E 3 39  ? 276.114 310.776 405.123 1.00 75.31  ? 39  PHE L CE2 1 
ATOM 4158 C CZ  . PHE E 3 39  ? 275.949 309.763 404.216 1.00 75.31  ? 39  PHE L CZ  1 
ATOM 4159 N N   . ILE E 3 40  ? 271.634 308.797 410.161 1.00 80.80  ? 40  ILE L N   1 
ATOM 4160 C CA  . ILE E 3 40  ? 271.087 308.354 411.439 1.00 80.80  ? 40  ILE L CA  1 
ATOM 4161 C C   . ILE E 3 40  ? 270.187 307.161 411.175 1.00 80.80  ? 40  ILE L C   1 
ATOM 4162 O O   . ILE E 3 40  ? 269.314 307.222 410.305 1.00 80.80  ? 40  ILE L O   1 
ATOM 4163 C CB  . ILE E 3 40  ? 270.307 309.476 412.152 1.00 80.80  ? 40  ILE L CB  1 
ATOM 4164 C CG1 . ILE E 3 40  ? 271.246 310.609 412.550 1.00 80.80  ? 40  ILE L CG1 1 
ATOM 4165 C CG2 . ILE E 3 40  ? 269.584 308.954 413.381 1.00 80.80  ? 40  ILE L CG2 1 
ATOM 4166 C CD1 . ILE E 3 40  ? 272.298 310.203 413.547 1.00 80.80  ? 40  ILE L CD1 1 
ATOM 4167 N N   . HIS E 3 41  ? 270.392 306.079 411.921 1.00 80.24  ? 41  HIS L N   1 
ATOM 4168 C CA  . HIS E 3 41  ? 269.683 304.835 411.686 1.00 80.24  ? 41  HIS L CA  1 
ATOM 4169 C C   . HIS E 3 41  ? 268.911 304.438 412.935 1.00 80.24  ? 41  HIS L C   1 
ATOM 4170 O O   . HIS E 3 41  ? 269.215 304.892 414.036 1.00 80.24  ? 41  HIS L O   1 
ATOM 4171 C CB  . HIS E 3 41  ? 270.675 303.753 411.284 1.00 80.24  ? 41  HIS L CB  1 
ATOM 4172 C CG  . HIS E 3 41  ? 271.606 304.195 410.204 1.00 80.24  ? 41  HIS L CG  1 
ATOM 4173 N ND1 . HIS E 3 41  ? 271.230 304.275 408.882 1.00 80.24  ? 41  HIS L ND1 1 
ATOM 4174 C CD2 . HIS E 3 41  ? 272.879 304.645 410.260 1.00 80.24  ? 41  HIS L CD2 1 
ATOM 4175 C CE1 . HIS E 3 41  ? 272.243 304.724 408.165 1.00 80.24  ? 41  HIS L CE1 1 
ATOM 4176 N NE2 . HIS E 3 41  ? 273.257 304.954 408.977 1.00 80.24  ? 41  HIS L NE2 1 
ATOM 4177 N N   . TRP E 3 42  ? 267.898 303.591 412.760 1.00 86.16  ? 42  TRP L N   1 
ATOM 4178 C CA  . TRP E 3 42  ? 266.988 303.218 413.837 1.00 86.16  ? 42  TRP L CA  1 
ATOM 4179 C C   . TRP E 3 42  ? 266.939 301.706 413.991 1.00 86.16  ? 42  TRP L C   1 
ATOM 4180 O O   . TRP E 3 42  ? 266.865 300.981 412.996 1.00 86.16  ? 42  TRP L O   1 
ATOM 4181 C CB  . TRP E 3 42  ? 265.580 303.756 413.581 1.00 86.16  ? 42  TRP L CB  1 
ATOM 4182 C CG  . TRP E 3 42  ? 265.479 305.228 413.730 1.00 86.16  ? 42  TRP L CG  1 
ATOM 4183 C CD1 . TRP E 3 42  ? 265.453 306.155 412.736 1.00 86.16  ? 42  TRP L CD1 1 
ATOM 4184 C CD2 . TRP E 3 42  ? 265.412 305.953 414.958 1.00 86.16  ? 42  TRP L CD2 1 
ATOM 4185 N NE1 . TRP E 3 42  ? 265.362 307.417 413.267 1.00 86.16  ? 42  TRP L NE1 1 
ATOM 4186 C CE2 . TRP E 3 42  ? 265.335 307.318 414.633 1.00 86.16  ? 42  TRP L CE2 1 
ATOM 4187 C CE3 . TRP E 3 42  ? 265.400 305.578 416.302 1.00 86.16  ? 42  TRP L CE3 1 
ATOM 4188 C CZ2 . TRP E 3 42  ? 265.250 308.308 415.601 1.00 86.16  ? 42  TRP L CZ2 1 
ATOM 4189 C CZ3 . TRP E 3 42  ? 265.317 306.556 417.260 1.00 86.16  ? 42  TRP L CZ3 1 
ATOM 4190 C CH2 . TRP E 3 42  ? 265.239 307.908 416.907 1.00 86.16  ? 42  TRP L CH2 1 
ATOM 4191 N N   . TYR E 3 43  ? 266.957 301.237 415.236 1.00 83.97  ? 43  TYR L N   1 
ATOM 4192 C CA  . TYR E 3 43  ? 266.982 299.815 415.532 1.00 83.97  ? 43  TYR L CA  1 
ATOM 4193 C C   . TYR E 3 43  ? 265.861 299.433 416.488 1.00 83.97  ? 43  TYR L C   1 
ATOM 4194 O O   . TYR E 3 43  ? 265.279 300.276 417.170 1.00 83.97  ? 43  TYR L O   1 
ATOM 4195 C CB  . TYR E 3 43  ? 268.325 299.396 416.132 1.00 83.97  ? 43  TYR L CB  1 
ATOM 4196 C CG  . TYR E 3 43  ? 269.472 299.449 415.160 1.00 83.97  ? 43  TYR L CG  1 
ATOM 4197 C CD1 . TYR E 3 43  ? 269.645 298.452 414.212 1.00 83.97  ? 43  TYR L CD1 1 
ATOM 4198 C CD2 . TYR E 3 43  ? 270.394 300.480 415.205 1.00 83.97  ? 43  TYR L CD2 1 
ATOM 4199 C CE1 . TYR E 3 43  ? 270.693 298.493 413.321 1.00 83.97  ? 43  TYR L CE1 1 
ATOM 4200 C CE2 . TYR E 3 43  ? 271.445 300.527 414.324 1.00 83.97  ? 43  TYR L CE2 1 
ATOM 4201 C CZ  . TYR E 3 43  ? 271.590 299.535 413.385 1.00 83.97  ? 43  TYR L CZ  1 
ATOM 4202 O OH  . TYR E 3 43  ? 272.641 299.589 412.509 1.00 83.97  ? 43  TYR L OH  1 
ATOM 4203 N N   . GLN E 3 44  ? 265.572 298.136 416.525 1.00 90.59  ? 44  GLN L N   1 
ATOM 4204 C CA  . GLN E 3 44  ? 264.560 297.561 417.401 1.00 90.59  ? 44  GLN L CA  1 
ATOM 4205 C C   . GLN E 3 44  ? 265.110 296.275 417.993 1.00 90.59  ? 44  GLN L C   1 
ATOM 4206 O O   . GLN E 3 44  ? 265.507 295.374 417.249 1.00 90.59  ? 44  GLN L O   1 
ATOM 4207 C CB  . GLN E 3 44  ? 263.270 297.261 416.642 1.00 90.59  ? 44  GLN L CB  1 
ATOM 4208 C CG  . GLN E 3 44  ? 262.144 296.760 417.512 1.00 90.59  ? 44  GLN L CG  1 
ATOM 4209 C CD  . GLN E 3 44  ? 260.891 296.470 416.720 1.00 90.59  ? 44  GLN L CD  1 
ATOM 4210 O OE1 . GLN E 3 44  ? 260.880 296.578 415.497 1.00 90.59  ? 44  GLN L OE1 1 
ATOM 4211 N NE2 . GLN E 3 44  ? 259.824 296.104 417.412 1.00 90.59  ? 44  GLN L NE2 1 
ATOM 4212 N N   . GLN E 3 45  ? 265.124 296.180 419.318 1.00 93.03  ? 45  GLN L N   1 
ATOM 4213 C CA  . GLN E 3 45  ? 265.646 294.995 419.988 1.00 93.03  ? 45  GLN L CA  1 
ATOM 4214 C C   . GLN E 3 45  ? 264.591 294.433 420.929 1.00 93.03  ? 45  GLN L C   1 
ATOM 4215 O O   . GLN E 3 45  ? 264.326 295.006 421.989 1.00 93.03  ? 45  GLN L O   1 
ATOM 4216 C CB  . GLN E 3 45  ? 266.929 295.305 420.754 1.00 93.03  ? 45  GLN L CB  1 
ATOM 4217 C CG  . GLN E 3 45  ? 267.571 294.065 421.325 1.00 93.03  ? 45  GLN L CG  1 
ATOM 4218 C CD  . GLN E 3 45  ? 268.838 294.353 422.088 1.00 93.03  ? 45  GLN L CD  1 
ATOM 4219 O OE1 . GLN E 3 45  ? 269.213 295.506 422.289 1.00 93.03  ? 45  GLN L OE1 1 
ATOM 4220 N NE2 . GLN E 3 45  ? 269.518 293.296 422.508 1.00 93.03  ? 45  GLN L NE2 1 
ATOM 4221 N N   . LYS E 3 46  ? 263.989 293.318 420.533 1.00 93.42  ? 46  LYS L N   1 
ATOM 4222 C CA  . LYS E 3 46  ? 263.214 292.514 421.456 1.00 93.42  ? 46  LYS L CA  1 
ATOM 4223 C C   . LYS E 3 46  ? 264.174 291.848 422.445 1.00 93.42  ? 46  LYS L C   1 
ATOM 4224 O O   . LYS E 3 46  ? 265.319 291.556 422.091 1.00 93.42  ? 46  LYS L O   1 
ATOM 4225 C CB  . LYS E 3 46  ? 262.407 291.480 420.673 1.00 93.42  ? 46  LYS L CB  1 
ATOM 4226 C CG  . LYS E 3 46  ? 261.333 292.112 419.802 1.00 93.42  ? 46  LYS L CG  1 
ATOM 4227 C CD  . LYS E 3 46  ? 260.557 291.077 419.014 1.00 93.42  ? 46  LYS L CD  1 
ATOM 4228 C CE  . LYS E 3 46  ? 259.528 291.737 418.111 1.00 93.42  ? 46  LYS L CE  1 
ATOM 4229 N NZ  . LYS E 3 46  ? 258.781 290.746 417.287 1.00 93.42  ? 46  LYS L NZ  1 
ATOM 4230 N N   . PRO E 3 47  ? 263.745 291.616 423.698 1.00 94.30  ? 47  PRO L N   1 
ATOM 4231 C CA  . PRO E 3 47  ? 264.722 291.294 424.759 1.00 94.30  ? 47  PRO L CA  1 
ATOM 4232 C C   . PRO E 3 47  ? 265.395 289.934 424.634 1.00 94.30  ? 47  PRO L C   1 
ATOM 4233 O O   . PRO E 3 47  ? 266.408 289.711 425.309 1.00 94.30  ? 47  PRO L O   1 
ATOM 4234 C CB  . PRO E 3 47  ? 263.883 291.372 426.039 1.00 94.30  ? 47  PRO L CB  1 
ATOM 4235 C CG  . PRO E 3 47  ? 262.501 291.098 425.595 1.00 94.30  ? 47  PRO L CG  1 
ATOM 4236 C CD  . PRO E 3 47  ? 262.378 291.717 424.241 1.00 94.30  ? 47  PRO L CD  1 
ATOM 4237 N N   . GLY E 3 48  ? 264.890 289.029 423.803 1.00 93.11  ? 48  GLY L N   1 
ATOM 4238 C CA  . GLY E 3 48  ? 265.541 287.745 423.638 1.00 93.11  ? 48  GLY L CA  1 
ATOM 4239 C C   . GLY E 3 48  ? 266.081 287.531 422.240 1.00 93.11  ? 48  GLY L C   1 
ATOM 4240 O O   . GLY E 3 48  ? 266.328 286.394 421.828 1.00 93.11  ? 48  GLY L O   1 
ATOM 4241 N N   . GLN E 3 49  ? 266.271 288.616 421.503 1.00 91.75  ? 49  GLN L N   1 
ATOM 4242 C CA  . GLN E 3 49  ? 266.619 288.568 420.094 1.00 91.75  ? 49  GLN L CA  1 
ATOM 4243 C C   . GLN E 3 49  ? 267.739 289.559 419.816 1.00 91.75  ? 49  GLN L C   1 
ATOM 4244 O O   . GLN E 3 49  ? 267.922 290.521 420.571 1.00 91.75  ? 49  GLN L O   1 
ATOM 4245 C CB  . GLN E 3 49  ? 265.399 288.891 419.219 1.00 91.75  ? 49  GLN L CB  1 
ATOM 4246 C CG  . GLN E 3 49  ? 264.315 287.832 419.232 1.00 91.75  ? 49  GLN L CG  1 
ATOM 4247 C CD  . GLN E 3 49  ? 263.141 288.211 418.361 1.00 91.75  ? 49  GLN L CD  1 
ATOM 4248 O OE1 . GLN E 3 49  ? 263.109 289.300 417.789 1.00 91.75  ? 49  GLN L OE1 1 
ATOM 4249 N NE2 . GLN E 3 49  ? 262.168 287.317 418.254 1.00 91.75  ? 49  GLN L NE2 1 
ATOM 4250 N N   . PRO E 3 50  ? 268.510 289.347 418.752 1.00 86.45  ? 50  PRO L N   1 
ATOM 4251 C CA  . PRO E 3 50  ? 269.416 290.394 418.273 1.00 86.45  ? 50  PRO L CA  1 
ATOM 4252 C C   . PRO E 3 50  ? 268.635 291.558 417.693 1.00 86.45  ? 50  PRO L C   1 
ATOM 4253 O O   . PRO E 3 50  ? 267.458 291.397 417.334 1.00 86.45  ? 50  PRO L O   1 
ATOM 4254 C CB  . PRO E 3 50  ? 270.234 289.678 417.190 1.00 86.45  ? 50  PRO L CB  1 
ATOM 4255 C CG  . PRO E 3 50  ? 269.395 288.549 416.764 1.00 86.45  ? 50  PRO L CG  1 
ATOM 4256 C CD  . PRO E 3 50  ? 268.689 288.097 417.996 1.00 86.45  ? 50  PRO L CD  1 
ATOM 4257 N N   . PRO E 3 51  ? 269.239 292.745 417.602 1.00 83.38  ? 51  PRO L N   1 
ATOM 4258 C CA  . PRO E 3 51  ? 268.520 293.897 417.050 1.00 83.38  ? 51  PRO L CA  1 
ATOM 4259 C C   . PRO E 3 51  ? 268.217 293.734 415.569 1.00 83.38  ? 51  PRO L C   1 
ATOM 4260 O O   . PRO E 3 51  ? 268.919 293.032 414.841 1.00 83.38  ? 51  PRO L O   1 
ATOM 4261 C CB  . PRO E 3 51  ? 269.486 295.062 417.284 1.00 83.38  ? 51  PRO L CB  1 
ATOM 4262 C CG  . PRO E 3 51  ? 270.352 294.615 418.407 1.00 83.38  ? 51  PRO L CG  1 
ATOM 4263 C CD  . PRO E 3 51  ? 270.513 293.146 418.226 1.00 83.38  ? 51  PRO L CD  1 
ATOM 4264 N N   . LYS E 3 52  ? 267.133 294.370 415.138 1.00 83.73  ? 52  LYS L N   1 
ATOM 4265 C CA  . LYS E 3 52  ? 266.799 294.493 413.729 1.00 83.73  ? 52  LYS L CA  1 
ATOM 4266 C C   . LYS E 3 52  ? 266.889 295.949 413.309 1.00 83.73  ? 52  LYS L C   1 
ATOM 4267 O O   . LYS E 3 52  ? 266.846 296.858 414.137 1.00 83.73  ? 52  LYS L O   1 
ATOM 4268 C CB  . LYS E 3 52  ? 265.398 293.960 413.430 1.00 83.73  ? 52  LYS L CB  1 
ATOM 4269 C CG  . LYS E 3 52  ? 265.308 292.454 413.401 1.00 83.73  ? 52  LYS L CG  1 
ATOM 4270 C CD  . LYS E 3 52  ? 263.877 291.982 413.213 1.00 83.73  ? 52  LYS L CD  1 
ATOM 4271 C CE  . LYS E 3 52  ? 263.531 291.759 411.746 1.00 83.73  ? 52  LYS L CE  1 
ATOM 4272 N NZ  . LYS E 3 52  ? 263.350 293.019 410.972 1.00 83.73  ? 52  LYS L NZ  1 
ATOM 4273 N N   . LEU E 3 53  ? 267.012 296.159 412.005 1.00 83.03  ? 53  LEU L N   1 
ATOM 4274 C CA  . LEU E 3 53  ? 267.115 297.493 411.434 1.00 83.03  ? 53  LEU L CA  1 
ATOM 4275 C C   . LEU E 3 53  ? 265.742 297.939 410.959 1.00 83.03  ? 53  LEU L C   1 
ATOM 4276 O O   . LEU E 3 53  ? 265.080 297.219 410.206 1.00 83.03  ? 53  LEU L O   1 
ATOM 4277 C CB  . LEU E 3 53  ? 268.120 297.508 410.282 1.00 83.03  ? 53  LEU L CB  1 
ATOM 4278 C CG  . LEU E 3 53  ? 268.524 298.831 409.630 1.00 83.03  ? 53  LEU L CG  1 
ATOM 4279 C CD1 . LEU E 3 53  ? 269.959 298.740 409.252 1.00 83.03  ? 53  LEU L CD1 1 
ATOM 4280 C CD2 . LEU E 3 53  ? 267.725 299.112 408.377 1.00 83.03  ? 53  LEU L CD2 1 
ATOM 4281 N N   . LEU E 3 54  ? 265.315 299.120 411.398 1.00 86.40  ? 54  LEU L N   1 
ATOM 4282 C CA  . LEU E 3 54  ? 264.026 299.659 410.986 1.00 86.40  ? 54  LEU L CA  1 
ATOM 4283 C C   . LEU E 3 54  ? 264.162 300.720 409.903 1.00 86.40  ? 54  LEU L C   1 
ATOM 4284 O O   . LEU E 3 54  ? 263.641 300.561 408.797 1.00 86.40  ? 54  LEU L O   1 
ATOM 4285 C CB  . LEU E 3 54  ? 263.298 300.251 412.191 1.00 86.40  ? 54  LEU L CB  1 
ATOM 4286 C CG  . LEU E 3 54  ? 262.939 299.270 413.292 1.00 86.40  ? 54  LEU L CG  1 
ATOM 4287 C CD1 . LEU E 3 54  ? 262.295 300.038 414.411 1.00 86.40  ? 54  LEU L CD1 1 
ATOM 4288 C CD2 . LEU E 3 54  ? 262.029 298.186 412.760 1.00 86.40  ? 54  LEU L CD2 1 
ATOM 4289 N N   . ILE E 3 55  ? 264.865 301.806 410.206 1.00 83.74  ? 55  ILE L N   1 
ATOM 4290 C CA  . ILE E 3 55  ? 264.929 302.971 409.338 1.00 83.74  ? 55  ILE L CA  1 
ATOM 4291 C C   . ILE E 3 55  ? 266.391 303.302 409.111 1.00 83.74  ? 55  ILE L C   1 
ATOM 4292 O O   . ILE E 3 55  ? 267.106 303.633 410.061 1.00 83.74  ? 55  ILE L O   1 
ATOM 4293 C CB  . ILE E 3 55  ? 264.198 304.179 409.942 1.00 83.74  ? 55  ILE L CB  1 
ATOM 4294 C CG1 . ILE E 3 55  ? 262.714 303.883 410.112 1.00 83.74  ? 55  ILE L CG1 1 
ATOM 4295 C CG2 . ILE E 3 55  ? 264.382 305.399 409.073 1.00 83.74  ? 55  ILE L CG2 1 
ATOM 4296 C CD1 . ILE E 3 55  ? 261.992 304.924 410.896 1.00 83.74  ? 55  ILE L CD1 1 
ATOM 4297 N N   . TYR E 3 56  ? 266.838 303.210 407.867 1.00 79.10  ? 56  TYR L N   1 
ATOM 4298 C CA  . TYR E 3 56  ? 268.190 303.597 407.510 1.00 79.10  ? 56  TYR L CA  1 
ATOM 4299 C C   . TYR E 3 56  ? 268.168 304.928 406.774 1.00 79.10  ? 56  TYR L C   1 
ATOM 4300 O O   . TYR E 3 56  ? 267.202 305.249 406.080 1.00 79.10  ? 56  TYR L O   1 
ATOM 4301 C CB  . TYR E 3 56  ? 268.885 302.514 406.675 1.00 79.10  ? 56  TYR L CB  1 
ATOM 4302 C CG  . TYR E 3 56  ? 268.213 302.131 405.377 1.00 79.10  ? 56  TYR L CG  1 
ATOM 4303 C CD1 . TYR E 3 56  ? 267.251 301.134 405.343 1.00 79.10  ? 56  TYR L CD1 1 
ATOM 4304 C CD2 . TYR E 3 56  ? 268.583 302.722 404.180 1.00 79.10  ? 56  TYR L CD2 1 
ATOM 4305 C CE1 . TYR E 3 56  ? 266.648 300.769 404.162 1.00 79.10  ? 56  TYR L CE1 1 
ATOM 4306 C CE2 . TYR E 3 56  ? 267.988 302.360 402.994 1.00 79.10  ? 56  TYR L CE2 1 
ATOM 4307 C CZ  . TYR E 3 56  ? 267.021 301.384 402.993 1.00 79.10  ? 56  TYR L CZ  1 
ATOM 4308 O OH  . TYR E 3 56  ? 266.422 301.018 401.815 1.00 79.10  ? 56  TYR L OH  1 
ATOM 4309 N N   . LEU E 3 57  ? 269.231 305.713 406.993 1.00 78.34  ? 57  LEU L N   1 
ATOM 4310 C CA  . LEU E 3 57  ? 269.418 307.063 406.445 1.00 78.34  ? 57  LEU L CA  1 
ATOM 4311 C C   . LEU E 3 57  ? 268.294 308.015 406.848 1.00 78.34  ? 57  LEU L C   1 
ATOM 4312 O O   . LEU E 3 57  ? 267.923 308.905 406.078 1.00 78.34  ? 57  LEU L O   1 
ATOM 4313 C CB  . LEU E 3 57  ? 269.571 307.036 404.923 1.00 78.34  ? 57  LEU L CB  1 
ATOM 4314 C CG  . LEU E 3 57  ? 270.712 306.165 404.406 1.00 78.34  ? 57  LEU L CG  1 
ATOM 4315 C CD1 . LEU E 3 57  ? 270.657 306.115 402.911 1.00 78.34  ? 57  LEU L CD1 1 
ATOM 4316 C CD2 . LEU E 3 57  ? 272.049 306.672 404.879 1.00 78.34  ? 57  LEU L CD2 1 
ATOM 4317 N N   . ALA E 3 58  ? 267.710 307.770 408.028 1.00 80.90  ? 58  ALA L N   1 
ATOM 4318 C CA  . ALA E 3 58  ? 266.734 308.594 408.745 1.00 80.90  ? 58  ALA L CA  1 
ATOM 4319 C C   . ALA E 3 58  ? 265.370 308.717 408.071 1.00 80.90  ? 58  ALA L C   1 
ATOM 4320 O O   . ALA E 3 58  ? 264.455 309.296 408.661 1.00 80.90  ? 58  ALA L O   1 
ATOM 4321 C CB  . ALA E 3 58  ? 267.297 309.994 409.018 1.00 80.90  ? 58  ALA L CB  1 
ATOM 4322 N N   . SER E 3 59  ? 265.197 308.189 406.867 1.00 81.00  ? 59  SER L N   1 
ATOM 4323 C CA  . SER E 3 59  ? 263.878 308.250 406.250 1.00 81.00  ? 59  SER L CA  1 
ATOM 4324 C C   . SER E 3 59  ? 263.502 307.037 405.411 1.00 81.00  ? 59  SER L C   1 
ATOM 4325 O O   . SER E 3 59  ? 262.414 307.048 404.831 1.00 81.00  ? 59  SER L O   1 
ATOM 4326 C CB  . SER E 3 59  ? 263.773 309.515 405.389 1.00 81.00  ? 59  SER L CB  1 
ATOM 4327 O OG  . SER E 3 59  ? 264.639 309.441 404.273 1.00 81.00  ? 59  SER L OG  1 
ATOM 4328 N N   . HIS E 3 60  ? 264.327 306.001 405.319 1.00 80.68  ? 60  HIS L N   1 
ATOM 4329 C CA  . HIS E 3 60  ? 264.079 304.888 404.410 1.00 80.68  ? 60  HIS L CA  1 
ATOM 4330 C C   . HIS E 3 60  ? 263.762 303.639 405.217 1.00 80.68  ? 60  HIS L C   1 
ATOM 4331 O O   . HIS E 3 60  ? 264.558 303.230 406.065 1.00 80.68  ? 60  HIS L O   1 
ATOM 4332 C CB  . HIS E 3 60  ? 265.281 304.633 403.503 1.00 80.68  ? 60  HIS L CB  1 
ATOM 4333 C CG  . HIS E 3 60  ? 265.614 305.769 402.591 1.00 80.68  ? 60  HIS L CG  1 
ATOM 4334 N ND1 . HIS E 3 60  ? 264.889 306.051 401.455 1.00 80.68  ? 60  HIS L ND1 1 
ATOM 4335 C CD2 . HIS E 3 60  ? 266.610 306.685 402.638 1.00 80.68  ? 60  HIS L CD2 1 
ATOM 4336 C CE1 . HIS E 3 60  ? 265.416 307.098 400.847 1.00 80.68  ? 60  HIS L CE1 1 
ATOM 4337 N NE2 . HIS E 3 60  ? 266.464 307.500 401.543 1.00 80.68  ? 60  HIS L NE2 1 
ATOM 4338 N N   . LEU E 3 61  ? 262.616 303.028 404.936 1.00 87.82  ? 61  LEU L N   1 
ATOM 4339 C CA  . LEU E 3 61  ? 262.203 301.822 405.635 1.00 87.82  ? 61  LEU L CA  1 
ATOM 4340 C C   . LEU E 3 61  ? 262.838 300.585 405.023 1.00 87.82  ? 61  LEU L C   1 
ATOM 4341 O O   . LEU E 3 61  ? 262.852 300.417 403.802 1.00 87.82  ? 61  LEU L O   1 
ATOM 4342 C CB  . LEU E 3 61  ? 260.684 301.675 405.599 1.00 87.82  ? 61  LEU L CB  1 
ATOM 4343 C CG  . LEU E 3 61  ? 259.863 302.672 406.409 1.00 87.82  ? 61  LEU L CG  1 
ATOM 4344 C CD1 . LEU E 3 61  ? 258.397 302.486 406.103 1.00 87.82  ? 61  LEU L CD1 1 
ATOM 4345 C CD2 . LEU E 3 61  ? 260.122 302.469 407.879 1.00 87.82  ? 61  LEU L CD2 1 
ATOM 4346 N N   . GLU E 3 62  ? 263.352 299.715 405.887 1.00 91.86  ? 62  GLU L N   1 
ATOM 4347 C CA  . GLU E 3 62  ? 263.875 298.423 405.479 1.00 91.86  ? 62  GLU L CA  1 
ATOM 4348 C C   . GLU E 3 62  ? 262.732 297.548 404.961 1.00 91.86  ? 62  GLU L C   1 
ATOM 4349 O O   . GLU E 3 62  ? 261.567 297.739 405.317 1.00 91.86  ? 62  GLU L O   1 
ATOM 4350 C CB  . GLU E 3 62  ? 264.606 297.779 406.665 1.00 91.86  ? 62  GLU L CB  1 
ATOM 4351 C CG  . GLU E 3 62  ? 265.355 296.480 406.403 1.00 91.86  ? 62  GLU L CG  1 
ATOM 4352 C CD  . GLU E 3 62  ? 266.522 296.643 405.446 1.00 91.86  ? 62  GLU L CD  1 
ATOM 4353 O OE1 . GLU E 3 62  ? 267.111 297.740 405.391 1.00 91.86  ? 62  GLU L OE1 1 
ATOM 4354 O OE2 . GLU E 3 62  ? 266.848 295.667 404.739 1.00 91.86  ? 62  GLU L OE2 1 
ATOM 4355 N N   . SER E 3 63  ? 263.074 296.595 404.085 1.00 96.01  ? 63  SER L N   1 
ATOM 4356 C CA  . SER E 3 63  ? 262.066 295.819 403.366 1.00 96.01  ? 63  SER L CA  1 
ATOM 4357 C C   . SER E 3 63  ? 261.258 294.901 404.279 1.00 96.01  ? 63  SER L C   1 
ATOM 4358 O O   . SER E 3 63  ? 260.142 294.510 403.921 1.00 96.01  ? 63  SER L O   1 
ATOM 4359 C CB  . SER E 3 63  ? 262.731 294.999 402.264 1.00 96.01  ? 63  SER L CB  1 
ATOM 4360 O OG  . SER E 3 63  ? 261.772 294.218 401.576 1.00 96.01  ? 63  SER L OG  1 
ATOM 4361 N N   . GLY E 3 64  ? 261.788 294.547 405.447 1.00 98.66  ? 64  GLY L N   1 
ATOM 4362 C CA  . GLY E 3 64  ? 261.019 293.747 406.384 1.00 98.66  ? 64  GLY L CA  1 
ATOM 4363 C C   . GLY E 3 64  ? 260.107 294.529 407.303 1.00 98.66  ? 64  GLY L C   1 
ATOM 4364 O O   . GLY E 3 64  ? 259.318 293.923 408.034 1.00 98.66  ? 64  GLY L O   1 
ATOM 4365 N N   . VAL E 3 65  ? 260.193 295.851 407.279 1.00 97.68  ? 65  VAL L N   1 
ATOM 4366 C CA  . VAL E 3 65  ? 259.400 296.689 408.185 1.00 97.68  ? 65  VAL L CA  1 
ATOM 4367 C C   . VAL E 3 65  ? 257.957 296.730 407.696 1.00 97.68  ? 65  VAL L C   1 
ATOM 4368 O O   . VAL E 3 65  ? 257.725 296.878 406.483 1.00 97.68  ? 65  VAL L O   1 
ATOM 4369 C CB  . VAL E 3 65  ? 260.009 298.092 408.266 1.00 97.68  ? 65  VAL L CB  1 
ATOM 4370 C CG1 . VAL E 3 65  ? 259.163 299.036 409.103 1.00 97.68  ? 65  VAL L CG1 1 
ATOM 4371 C CG2 . VAL E 3 65  ? 261.407 298.006 408.842 1.00 97.68  ? 65  VAL L CG2 1 
ATOM 4372 N N   . PRO E 3 66  ? 256.953 296.594 408.587 1.00 101.79 ? 66  PRO L N   1 
ATOM 4373 C CA  . PRO E 3 66  ? 255.548 296.601 408.145 1.00 101.79 ? 66  PRO L CA  1 
ATOM 4374 C C   . PRO E 3 66  ? 254.962 297.974 407.836 1.00 101.79 ? 66  PRO L C   1 
ATOM 4375 O O   . PRO E 3 66  ? 253.735 298.114 407.789 1.00 101.79 ? 66  PRO L O   1 
ATOM 4376 C CB  . PRO E 3 66  ? 254.817 295.956 409.327 1.00 101.79 ? 66  PRO L CB  1 
ATOM 4377 C CG  . PRO E 3 66  ? 255.688 296.236 410.497 1.00 101.79 ? 66  PRO L CG  1 
ATOM 4378 C CD  . PRO E 3 66  ? 257.086 296.174 409.992 1.00 101.79 ? 66  PRO L CD  1 
ATOM 4379 N N   . ALA E 3 67  ? 255.818 298.987 407.682 1.00 103.36 ? 67  ALA L N   1 
ATOM 4380 C CA  . ALA E 3 67  ? 255.501 300.304 407.128 1.00 103.36 ? 67  ALA L CA  1 
ATOM 4381 C C   . ALA E 3 67  ? 254.538 301.114 407.985 1.00 103.36 ? 67  ALA L C   1 
ATOM 4382 O O   . ALA E 3 67  ? 253.773 301.924 407.456 1.00 103.36 ? 67  ALA L O   1 
ATOM 4383 C CB  . ALA E 3 67  ? 254.962 300.206 405.693 1.00 103.36 ? 67  ALA L CB  1 
ATOM 4384 N N   . ARG E 3 68  ? 254.549 300.920 409.300 1.00 104.53 ? 68  ARG L N   1 
ATOM 4385 C CA  . ARG E 3 68  ? 253.925 301.875 410.203 1.00 104.53 ? 68  ARG L CA  1 
ATOM 4386 C C   . ARG E 3 68  ? 254.952 302.732 410.928 1.00 104.53 ? 68  ARG L C   1 
ATOM 4387 O O   . ARG E 3 68  ? 254.607 303.405 411.904 1.00 104.53 ? 68  ARG L O   1 
ATOM 4388 C CB  . ARG E 3 68  ? 253.025 301.153 411.214 1.00 104.53 ? 68  ARG L CB  1 
ATOM 4389 C CG  . ARG E 3 68  ? 253.737 300.247 412.197 1.00 104.53 ? 68  ARG L CG  1 
ATOM 4390 C CD  . ARG E 3 68  ? 252.723 299.573 413.092 1.00 104.53 ? 68  ARG L CD  1 
ATOM 4391 N NE  . ARG E 3 68  ? 251.866 298.688 412.314 1.00 104.53 ? 68  ARG L NE  1 
ATOM 4392 C CZ  . ARG E 3 68  ? 252.115 297.399 412.111 1.00 104.53 ? 68  ARG L CZ  1 
ATOM 4393 N NH1 . ARG E 3 68  ? 253.185 296.838 412.656 1.00 104.53 ? 68  ARG L NH1 1 
ATOM 4394 N NH2 . ARG E 3 68  ? 251.286 296.669 411.380 1.00 104.53 ? 68  ARG L NH2 1 
ATOM 4395 N N   . PHE E 3 69  ? 256.197 302.721 410.470 1.00 99.93  ? 69  PHE L N   1 
ATOM 4396 C CA  . PHE E 3 69  ? 257.247 303.528 411.064 1.00 99.93  ? 69  PHE L CA  1 
ATOM 4397 C C   . PHE E 3 69  ? 257.631 304.652 410.110 1.00 99.93  ? 69  PHE L C   1 
ATOM 4398 O O   . PHE E 3 69  ? 257.438 304.556 408.896 1.00 99.93  ? 69  PHE L O   1 
ATOM 4399 C CB  . PHE E 3 69  ? 258.466 302.659 411.376 1.00 99.93  ? 69  PHE L CB  1 
ATOM 4400 C CG  . PHE E 3 69  ? 258.234 301.641 412.463 1.00 99.93  ? 69  PHE L CG  1 
ATOM 4401 C CD1 . PHE E 3 69  ? 257.229 301.807 413.398 1.00 99.93  ? 69  PHE L CD1 1 
ATOM 4402 C CD2 . PHE E 3 69  ? 259.007 300.496 412.526 1.00 99.93  ? 69  PHE L CD2 1 
ATOM 4403 C CE1 . PHE E 3 69  ? 257.018 300.864 414.386 1.00 99.93  ? 69  PHE L CE1 1 
ATOM 4404 C CE2 . PHE E 3 69  ? 258.792 299.550 413.510 1.00 99.93  ? 69  PHE L CE2 1 
ATOM 4405 C CZ  . PHE E 3 69  ? 257.798 299.737 414.439 1.00 99.93  ? 69  PHE L CZ  1 
ATOM 4406 N N   . SER E 3 70  ? 258.181 305.726 410.670 1.00 98.37  ? 70  SER L N   1 
ATOM 4407 C CA  . SER E 3 70  ? 258.609 306.861 409.865 1.00 98.37  ? 70  SER L CA  1 
ATOM 4408 C C   . SER E 3 70  ? 259.674 307.627 410.632 1.00 98.37  ? 70  SER L C   1 
ATOM 4409 O O   . SER E 3 70  ? 259.901 307.388 411.818 1.00 98.37  ? 70  SER L O   1 
ATOM 4410 C CB  . SER E 3 70  ? 257.437 307.783 409.515 1.00 98.37  ? 70  SER L CB  1 
ATOM 4411 O OG  . SER E 3 70  ? 256.920 308.404 410.678 1.00 98.37  ? 70  SER L OG  1 
ATOM 4412 N N   . GLY E 3 71  ? 260.321 308.555 409.936 1.00 91.76  ? 71  GLY L N   1 
ATOM 4413 C CA  . GLY E 3 71  ? 261.359 309.357 410.553 1.00 91.76  ? 71  GLY L CA  1 
ATOM 4414 C C   . GLY E 3 71  ? 261.641 310.603 409.745 1.00 91.76  ? 71  GLY L C   1 
ATOM 4415 O O   . GLY E 3 71  ? 261.372 310.661 408.541 1.00 91.76  ? 71  GLY L O   1 
ATOM 4416 N N   . SER E 3 72  ? 262.192 311.602 410.429 1.00 93.69  ? 72  SER L N   1 
ATOM 4417 C CA  . SER E 3 72  ? 262.591 312.857 409.803 1.00 93.69  ? 72  SER L CA  1 
ATOM 4418 C C   . SER E 3 72  ? 263.585 313.555 410.716 1.00 93.69  ? 72  SER L C   1 
ATOM 4419 O O   . SER E 3 72  ? 263.825 313.127 411.846 1.00 93.69  ? 72  SER L O   1 
ATOM 4420 C CB  . SER E 3 72  ? 261.388 313.762 409.524 1.00 93.69  ? 72  SER L CB  1 
ATOM 4421 O OG  . SER E 3 72  ? 260.791 314.189 410.733 1.00 93.69  ? 72  SER L OG  1 
ATOM 4422 N N   . GLY E 3 73  ? 264.157 314.635 410.214 1.00 92.91  ? 73  GLY L N   1 
ATOM 4423 C CA  . GLY E 3 73  ? 265.075 315.437 411.000 1.00 92.91  ? 73  GLY L CA  1 
ATOM 4424 C C   . GLY E 3 73  ? 266.117 316.096 410.122 1.00 92.91  ? 73  GLY L C   1 
ATOM 4425 O O   . GLY E 3 73  ? 266.242 315.806 408.937 1.00 92.91  ? 73  GLY L O   1 
ATOM 4426 N N   . SER E 3 74  ? 266.874 316.999 410.744 1.00 95.04  ? 74  SER L N   1 
ATOM 4427 C CA  . SER E 3 74  ? 267.894 317.763 410.036 1.00 95.04  ? 74  SER L CA  1 
ATOM 4428 C C   . SER E 3 74  ? 268.966 318.217 411.015 1.00 95.04  ? 74  SER L C   1 
ATOM 4429 O O   . SER E 3 74  ? 268.722 319.116 411.825 1.00 95.04  ? 74  SER L O   1 
ATOM 4430 C CB  . SER E 3 74  ? 267.279 318.972 409.325 1.00 95.04  ? 74  SER L CB  1 
ATOM 4431 O OG  . SER E 3 74  ? 266.782 319.914 410.260 1.00 95.04  ? 74  SER L OG  1 
ATOM 4432 N N   . ARG E 3 75  ? 270.109 317.529 410.986 1.00 92.94  ? 75  ARG L N   1 
ATOM 4433 C CA  . ARG E 3 75  ? 271.418 317.926 411.510 1.00 92.94  ? 75  ARG L CA  1 
ATOM 4434 C C   . ARG E 3 75  ? 271.560 317.952 413.030 1.00 92.94  ? 75  ARG L C   1 
ATOM 4435 O O   . ARG E 3 75  ? 272.688 317.957 413.532 1.00 92.94  ? 75  ARG L O   1 
ATOM 4436 C CB  . ARG E 3 75  ? 271.805 319.321 411.004 1.00 92.94  ? 75  ARG L CB  1 
ATOM 4437 C CG  . ARG E 3 75  ? 272.031 319.464 409.523 1.00 92.94  ? 75  ARG L CG  1 
ATOM 4438 C CD  . ARG E 3 75  ? 272.406 320.903 409.207 1.00 92.94  ? 75  ARG L CD  1 
ATOM 4439 N NE  . ARG E 3 75  ? 272.665 321.121 407.789 1.00 92.94  ? 75  ARG L NE  1 
ATOM 4440 C CZ  . ARG E 3 75  ? 271.742 321.499 406.911 1.00 92.94  ? 75  ARG L CZ  1 
ATOM 4441 N NH1 . ARG E 3 75  ? 270.492 321.699 407.305 1.00 92.94  ? 75  ARG L NH1 1 
ATOM 4442 N NH2 . ARG E 3 75  ? 272.070 321.678 405.639 1.00 92.94  ? 75  ARG L NH2 1 
ATOM 4443 N N   . THR E 3 76  ? 270.463 317.961 413.783 1.00 95.52  ? 76  THR L N   1 
ATOM 4444 C CA  . THR E 3 76  ? 270.548 317.885 415.237 1.00 95.52  ? 76  THR L CA  1 
ATOM 4445 C C   . THR E 3 76  ? 269.589 316.895 415.869 1.00 95.52  ? 76  THR L C   1 
ATOM 4446 O O   . THR E 3 76  ? 269.980 316.191 416.800 1.00 95.52  ? 76  THR L O   1 
ATOM 4447 C CB  . THR E 3 76  ? 270.290 319.258 415.890 1.00 95.52  ? 76  THR L CB  1 
ATOM 4448 O OG1 . THR E 3 76  ? 269.033 319.784 415.441 1.00 95.52  ? 76  THR L OG1 1 
ATOM 4449 C CG2 . THR E 3 76  ? 271.419 320.255 415.613 1.00 95.52  ? 76  THR L CG2 1 
ATOM 4450 N N   . ASP E 3 77  ? 268.356 316.812 415.385 1.00 97.27  ? 77  ASP L N   1 
ATOM 4451 C CA  . ASP E 3 77  ? 267.284 316.126 416.089 1.00 97.27  ? 77  ASP L CA  1 
ATOM 4452 C C   . ASP E 3 77  ? 266.481 315.272 415.125 1.00 97.27  ? 77  ASP L C   1 
ATOM 4453 O O   . ASP E 3 77  ? 265.975 315.768 414.116 1.00 97.27  ? 77  ASP L O   1 
ATOM 4454 C CB  . ASP E 3 77  ? 266.383 317.129 416.819 1.00 97.27  ? 77  ASP L CB  1 
ATOM 4455 C CG  . ASP E 3 77  ? 265.987 318.311 415.951 1.00 97.27  ? 77  ASP L CG  1 
ATOM 4456 O OD1 . ASP E 3 77  ? 266.539 318.461 414.839 1.00 97.27  ? 77  ASP L OD1 1 
ATOM 4457 O OD2 . ASP E 3 77  ? 265.114 319.091 416.385 1.00 97.27  ? 77  ASP L OD2 1 
ATOM 4458 N N   . PHE E 3 78  ? 266.353 313.992 415.450 1.00 93.29  ? 78  PHE L N   1 
ATOM 4459 C CA  . PHE E 3 78  ? 265.767 313.014 414.553 1.00 93.29  ? 78  PHE L CA  1 
ATOM 4460 C C   . PHE E 3 78  ? 264.724 312.215 415.316 1.00 93.29  ? 78  PHE L C   1 
ATOM 4461 O O   . PHE E 3 78  ? 264.993 311.678 416.391 1.00 93.29  ? 78  PHE L O   1 
ATOM 4462 C CB  . PHE E 3 78  ? 266.852 312.100 413.983 1.00 93.29  ? 78  PHE L CB  1 
ATOM 4463 C CG  . PHE E 3 78  ? 267.923 312.840 413.242 1.00 93.29  ? 78  PHE L CG  1 
ATOM 4464 C CD1 . PHE E 3 78  ? 267.750 313.196 411.917 1.00 93.29  ? 78  PHE L CD1 1 
ATOM 4465 C CD2 . PHE E 3 78  ? 269.094 313.210 413.882 1.00 93.29  ? 78  PHE L CD2 1 
ATOM 4466 C CE1 . PHE E 3 78  ? 268.731 313.895 411.240 1.00 93.29  ? 78  PHE L CE1 1 
ATOM 4467 C CE2 . PHE E 3 78  ? 270.076 313.913 413.209 1.00 93.29  ? 78  PHE L CE2 1 
ATOM 4468 C CZ  . PHE E 3 78  ? 269.900 314.248 411.889 1.00 93.29  ? 78  PHE L CZ  1 
ATOM 4469 N N   . THR E 3 79  ? 263.523 312.134 414.751 1.00 96.28  ? 79  THR L N   1 
ATOM 4470 C CA  . THR E 3 79  ? 262.401 311.542 415.462 1.00 96.28  ? 79  THR L CA  1 
ATOM 4471 C C   . THR E 3 79  ? 261.958 310.264 414.770 1.00 96.28  ? 79  THR L C   1 
ATOM 4472 O O   . THR E 3 79  ? 262.364 309.960 413.647 1.00 96.28  ? 79  THR L O   1 
ATOM 4473 C CB  . THR E 3 79  ? 261.214 312.509 415.576 1.00 96.28  ? 79  THR L CB  1 
ATOM 4474 O OG1 . THR E 3 79  ? 260.718 312.821 414.269 1.00 96.28  ? 79  THR L OG1 1 
ATOM 4475 C CG2 . THR E 3 79  ? 261.632 313.789 416.281 1.00 96.28  ? 79  THR L CG2 1 
ATOM 4476 N N   . LEU E 3 80  ? 261.122 309.507 415.476 1.00 97.58  ? 80  LEU L N   1 
ATOM 4477 C CA  . LEU E 3 80  ? 260.493 308.297 414.966 1.00 97.58  ? 80  LEU L CA  1 
ATOM 4478 C C   . LEU E 3 80  ? 259.063 308.264 415.482 1.00 97.58  ? 80  LEU L C   1 
ATOM 4479 O O   . LEU E 3 80  ? 258.840 308.282 416.696 1.00 97.58  ? 80  LEU L O   1 
ATOM 4480 C CB  . LEU E 3 80  ? 261.273 307.042 415.395 1.00 97.58  ? 80  LEU L CB  1 
ATOM 4481 C CG  . LEU E 3 80  ? 260.875 305.660 414.862 1.00 97.58  ? 80  LEU L CG  1 
ATOM 4482 C CD1 . LEU E 3 80  ? 262.093 304.806 414.673 1.00 97.58  ? 80  LEU L CD1 1 
ATOM 4483 C CD2 . LEU E 3 80  ? 259.954 304.942 415.821 1.00 97.58  ? 80  LEU L CD2 1 
ATOM 4484 N N   . THR E 3 81  ? 258.098 308.216 414.566 1.00 102.21 ? 81  THR L N   1 
ATOM 4485 C CA  . THR E 3 81  ? 256.683 308.248 414.913 1.00 102.21 ? 81  THR L CA  1 
ATOM 4486 C C   . THR E 3 81  ? 256.039 306.934 414.504 1.00 102.21 ? 81  THR L C   1 
ATOM 4487 O O   . THR E 3 81  ? 256.276 306.440 413.397 1.00 102.21 ? 81  THR L O   1 
ATOM 4488 C CB  . THR E 3 81  ? 255.964 309.419 414.243 1.00 102.21 ? 81  THR L CB  1 
ATOM 4489 O OG1 . THR E 3 81  ? 256.070 309.297 412.820 1.00 102.21 ? 81  THR L OG1 1 
ATOM 4490 C CG2 . THR E 3 81  ? 256.561 310.743 414.687 1.00 102.21 ? 81  THR L CG2 1 
ATOM 4491 N N   . ILE E 3 82  ? 255.225 306.377 415.394 1.00 105.66 ? 82  ILE L N   1 
ATOM 4492 C CA  . ILE E 3 82  ? 254.532 305.119 415.156 1.00 105.66 ? 82  ILE L CA  1 
ATOM 4493 C C   . ILE E 3 82  ? 253.039 305.421 415.191 1.00 105.66 ? 82  ILE L C   1 
ATOM 4494 O O   . ILE E 3 82  ? 252.460 305.605 416.263 1.00 105.66 ? 82  ILE L O   1 
ATOM 4495 C CB  . ILE E 3 82  ? 254.908 304.063 416.195 1.00 105.66 ? 82  ILE L CB  1 
ATOM 4496 C CG1 . ILE E 3 82  ? 256.420 303.881 416.239 1.00 105.66 ? 82  ILE L CG1 1 
ATOM 4497 C CG2 . ILE E 3 82  ? 254.245 302.744 415.863 1.00 105.66 ? 82  ILE L CG2 1 
ATOM 4498 C CD1 . ILE E 3 82  ? 256.905 303.079 417.411 1.00 105.66 ? 82  ILE L CD1 1 
ATOM 4499 N N   . ASP E 3 83  ? 252.410 305.492 414.022 1.00 109.70 ? 83  ASP L N   1 
ATOM 4500 C CA  . ASP E 3 83  ? 250.959 305.550 413.975 1.00 109.70 ? 83  ASP L CA  1 
ATOM 4501 C C   . ASP E 3 83  ? 250.397 304.179 414.375 1.00 109.70 ? 83  ASP L C   1 
ATOM 4502 O O   . ASP E 3 83  ? 251.021 303.154 414.089 1.00 109.70 ? 83  ASP L O   1 
ATOM 4503 C CB  . ASP E 3 83  ? 250.504 306.032 412.591 1.00 109.70 ? 83  ASP L CB  1 
ATOM 4504 C CG  . ASP E 3 83  ? 251.053 305.202 411.444 1.00 109.70 ? 83  ASP L CG  1 
ATOM 4505 O OD1 . ASP E 3 83  ? 251.913 304.330 411.664 1.00 109.70 ? 83  ASP L OD1 1 
ATOM 4506 O OD2 . ASP E 3 83  ? 250.607 305.425 410.299 1.00 109.70 ? 83  ASP L OD2 1 
ATOM 4507 N N   . PRO E 3 84  ? 249.145 304.129 414.955 1.00 111.44 ? 84  PRO L N   1 
ATOM 4508 C CA  . PRO E 3 84  ? 248.909 303.400 416.224 1.00 111.44 ? 84  PRO L CA  1 
ATOM 4509 C C   . PRO E 3 84  ? 249.681 302.120 416.512 1.00 111.44 ? 84  PRO L C   1 
ATOM 4510 O O   . PRO E 3 84  ? 249.707 301.184 415.705 1.00 111.44 ? 84  PRO L O   1 
ATOM 4511 C CB  . PRO E 3 84  ? 247.408 303.086 416.160 1.00 111.44 ? 84  PRO L CB  1 
ATOM 4512 C CG  . PRO E 3 84  ? 246.842 304.136 415.321 1.00 111.44 ? 84  PRO L CG  1 
ATOM 4513 C CD  . PRO E 3 84  ? 247.865 304.392 414.267 1.00 111.44 ? 84  PRO L CD  1 
ATOM 4514 N N   . VAL E 3 85  ? 250.284 302.088 417.703 1.00 109.84 ? 85  VAL L N   1 
ATOM 4515 C CA  . VAL E 3 85  ? 251.163 301.027 418.185 1.00 109.84 ? 85  VAL L CA  1 
ATOM 4516 C C   . VAL E 3 85  ? 250.424 299.701 418.285 1.00 109.84 ? 85  VAL L C   1 
ATOM 4517 O O   . VAL E 3 85  ? 249.356 299.618 418.898 1.00 109.84 ? 85  VAL L O   1 
ATOM 4518 C CB  . VAL E 3 85  ? 251.757 301.418 419.552 1.00 109.84 ? 85  VAL L CB  1 
ATOM 4519 C CG1 . VAL E 3 85  ? 252.646 300.314 420.099 1.00 109.84 ? 85  VAL L CG1 1 
ATOM 4520 C CG2 . VAL E 3 85  ? 252.506 302.735 419.450 1.00 109.84 ? 85  VAL L CG2 1 
ATOM 4521 N N   . GLU E 3 86  ? 250.990 298.652 417.696 1.00 108.89 ? 86  GLU L N   1 
ATOM 4522 C CA  . GLU E 3 86  ? 250.421 297.318 417.764 1.00 108.89 ? 86  GLU L CA  1 
ATOM 4523 C C   . GLU E 3 86  ? 251.198 296.504 418.788 1.00 108.89 ? 86  GLU L C   1 
ATOM 4524 O O   . GLU E 3 86  ? 252.042 297.031 419.518 1.00 108.89 ? 86  GLU L O   1 
ATOM 4525 C CB  . GLU E 3 86  ? 250.423 296.638 416.392 1.00 108.89 ? 86  GLU L CB  1 
ATOM 4526 C CG  . GLU E 3 86  ? 249.499 297.296 415.388 1.00 108.89 ? 86  GLU L CG  1 
ATOM 4527 C CD  . GLU E 3 86  ? 249.456 296.555 414.071 1.00 108.89 ? 86  GLU L CD  1 
ATOM 4528 O OE1 . GLU E 3 86  ? 250.213 295.575 413.917 1.00 108.89 ? 86  GLU L OE1 1 
ATOM 4529 O OE2 . GLU E 3 86  ? 248.670 296.954 413.186 1.00 108.89 ? 86  GLU L OE2 1 
ATOM 4530 N N   . ALA E 3 87  ? 250.893 295.205 418.844 1.00 109.94 ? 87  ALA L N   1 
ATOM 4531 C CA  . ALA E 3 87  ? 251.401 294.361 419.921 1.00 109.94 ? 87  ALA L CA  1 
ATOM 4532 C C   . ALA E 3 87  ? 252.892 294.082 419.772 1.00 109.94 ? 87  ALA L C   1 
ATOM 4533 O O   . ALA E 3 87  ? 253.610 293.967 420.771 1.00 109.94 ? 87  ALA L O   1 
ATOM 4534 C CB  . ALA E 3 87  ? 250.617 293.050 419.966 1.00 109.94 ? 87  ALA L CB  1 
ATOM 4535 N N   . ASP E 3 88  ? 253.379 293.980 418.534 1.00 109.38 ? 88  ASP L N   1 
ATOM 4536 C CA  . ASP E 3 88  ? 254.778 293.619 418.319 1.00 109.38 ? 88  ASP L CA  1 
ATOM 4537 C C   . ASP E 3 88  ? 255.702 294.810 418.531 1.00 109.38 ? 88  ASP L C   1 
ATOM 4538 O O   . ASP E 3 88  ? 256.919 294.645 418.658 1.00 109.38 ? 88  ASP L O   1 
ATOM 4539 C CB  . ASP E 3 88  ? 254.964 293.056 416.912 1.00 109.38 ? 88  ASP L CB  1 
ATOM 4540 C CG  . ASP E 3 88  ? 254.318 291.700 416.737 1.00 109.38 ? 88  ASP L CG  1 
ATOM 4541 O OD1 . ASP E 3 88  ? 254.257 290.939 417.724 1.00 109.38 ? 88  ASP L OD1 1 
ATOM 4542 O OD2 . ASP E 3 88  ? 253.865 291.399 415.613 1.00 109.38 ? 88  ASP L OD2 1 
ATOM 4543 N N   . ASP E 3 89  ? 255.142 296.020 418.586 1.00 107.36 ? 89  ASP L N   1 
ATOM 4544 C CA  . ASP E 3 89  ? 255.975 297.215 418.564 1.00 107.36 ? 89  ASP L CA  1 
ATOM 4545 C C   . ASP E 3 89  ? 256.540 297.549 419.939 1.00 107.36 ? 89  ASP L C   1 
ATOM 4546 O O   . ASP E 3 89  ? 257.302 298.511 420.074 1.00 107.36 ? 89  ASP L O   1 
ATOM 4547 C CB  . ASP E 3 89  ? 255.175 298.393 418.015 1.00 107.36 ? 89  ASP L CB  1 
ATOM 4548 C CG  . ASP E 3 89  ? 254.746 298.184 416.574 1.00 107.36 ? 89  ASP L CG  1 
ATOM 4549 O OD1 . ASP E 3 89  ? 255.418 297.415 415.857 1.00 107.36 ? 89  ASP L OD1 1 
ATOM 4550 O OD2 . ASP E 3 89  ? 253.741 298.792 416.153 1.00 107.36 ? 89  ASP L OD2 1 
ATOM 4551 N N   . PHE E 3 90  ? 256.182 296.782 420.967 1.00 107.01 ? 90  PHE L N   1 
ATOM 4552 C CA  . PHE E 3 90  ? 256.714 297.009 422.305 1.00 107.01 ? 90  PHE L CA  1 
ATOM 4553 C C   . PHE E 3 90  ? 258.116 296.430 422.443 1.00 107.01 ? 90  PHE L C   1 
ATOM 4554 O O   . PHE E 3 90  ? 258.273 295.229 422.685 1.00 107.01 ? 90  PHE L O   1 
ATOM 4555 C CB  . PHE E 3 90  ? 255.790 296.398 423.360 1.00 107.01 ? 90  PHE L CB  1 
ATOM 4556 C CG  . PHE E 3 90  ? 254.451 297.061 423.445 1.00 107.01 ? 90  PHE L CG  1 
ATOM 4557 C CD1 . PHE E 3 90  ? 254.285 298.224 424.180 1.00 107.01 ? 90  PHE L CD1 1 
ATOM 4558 C CD2 . PHE E 3 90  ? 253.361 296.533 422.772 1.00 107.01 ? 90  PHE L CD2 1 
ATOM 4559 C CE1 . PHE E 3 90  ? 253.051 298.842 424.254 1.00 107.01 ? 90  PHE L CE1 1 
ATOM 4560 C CE2 . PHE E 3 90  ? 252.125 297.144 422.840 1.00 107.01 ? 90  PHE L CE2 1 
ATOM 4561 C CZ  . PHE E 3 90  ? 251.969 298.301 423.583 1.00 107.01 ? 90  PHE L CZ  1 
ATOM 4562 N N   . ALA E 3 91  ? 259.135 297.273 422.301 1.00 101.01 ? 91  ALA L N   1 
ATOM 4563 C CA  . ALA E 3 91  ? 260.519 296.837 422.408 1.00 101.01 ? 91  ALA L CA  1 
ATOM 4564 C C   . ALA E 3 91  ? 261.386 298.038 422.758 1.00 101.01 ? 91  ALA L C   1 
ATOM 4565 O O   . ALA E 3 91  ? 260.888 299.103 423.130 1.00 101.01 ? 91  ALA L O   1 
ATOM 4566 C CB  . ALA E 3 91  ? 260.996 296.176 421.111 1.00 101.01 ? 91  ALA L CB  1 
ATOM 4567 N N   . THR E 3 92  ? 262.695 297.852 422.646 1.00 98.16  ? 92  THR L N   1 
ATOM 4568 C CA  . THR E 3 92  ? 263.645 298.936 422.823 1.00 98.16  ? 92  THR L CA  1 
ATOM 4569 C C   . THR E 3 92  ? 264.044 299.503 421.466 1.00 98.16  ? 92  THR L C   1 
ATOM 4570 O O   . THR E 3 92  ? 263.934 298.838 420.434 1.00 98.16  ? 92  THR L O   1 
ATOM 4571 C CB  . THR E 3 92  ? 264.882 298.455 423.576 1.00 98.16  ? 92  THR L CB  1 
ATOM 4572 O OG1 . THR E 3 92  ? 265.563 297.473 422.792 1.00 98.16  ? 92  THR L OG1 1 
ATOM 4573 C CG2 . THR E 3 92  ? 264.481 297.836 424.895 1.00 98.16  ? 92  THR L CG2 1 
ATOM 4574 N N   . TYR E 3 93  ? 264.506 300.751 421.472 1.00 95.69  ? 93  TYR L N   1 
ATOM 4575 C CA  . TYR E 3 93  ? 264.827 301.447 420.233 1.00 95.69  ? 93  TYR L CA  1 
ATOM 4576 C C   . TYR E 3 93  ? 266.126 302.215 420.395 1.00 95.69  ? 93  TYR L C   1 
ATOM 4577 O O   . TYR E 3 93  ? 266.185 303.190 421.147 1.00 95.69  ? 93  TYR L O   1 
ATOM 4578 C CB  . TYR E 3 93  ? 263.693 302.388 419.828 1.00 95.69  ? 93  TYR L CB  1 
ATOM 4579 C CG  . TYR E 3 93  ? 262.438 301.661 419.428 1.00 95.69  ? 93  TYR L CG  1 
ATOM 4580 C CD1 . TYR E 3 93  ? 262.308 301.119 418.161 1.00 95.69  ? 93  TYR L CD1 1 
ATOM 4581 C CD2 . TYR E 3 93  ? 261.388 301.504 420.318 1.00 95.69  ? 93  TYR L CD2 1 
ATOM 4582 C CE1 . TYR E 3 93  ? 261.165 300.447 417.788 1.00 95.69  ? 93  TYR L CE1 1 
ATOM 4583 C CE2 . TYR E 3 93  ? 260.238 300.833 419.952 1.00 95.69  ? 93  TYR L CE2 1 
ATOM 4584 C CZ  . TYR E 3 93  ? 260.136 300.307 418.683 1.00 95.69  ? 93  TYR L CZ  1 
ATOM 4585 O OH  . TYR E 3 93  ? 259.001 299.637 418.305 1.00 95.69  ? 93  TYR L OH  1 
ATOM 4586 N N   . TYR E 3 94  ? 267.156 301.782 419.679 1.00 91.83  ? 94  TYR L N   1 
ATOM 4587 C CA  . TYR E 3 94  ? 268.444 302.449 419.647 1.00 91.83  ? 94  TYR L CA  1 
ATOM 4588 C C   . TYR E 3 94  ? 268.573 303.265 418.369 1.00 91.83  ? 94  TYR L C   1 
ATOM 4589 O O   . TYR E 3 94  ? 267.927 302.982 417.358 1.00 91.83  ? 94  TYR L O   1 
ATOM 4590 C CB  . TYR E 3 94  ? 269.590 301.437 419.717 1.00 91.83  ? 94  TYR L CB  1 
ATOM 4591 C CG  . TYR E 3 94  ? 269.716 300.715 421.034 1.00 91.83  ? 94  TYR L CG  1 
ATOM 4592 C CD1 . TYR E 3 94  ? 270.413 301.278 422.093 1.00 91.83  ? 94  TYR L CD1 1 
ATOM 4593 C CD2 . TYR E 3 94  ? 269.142 299.468 421.214 1.00 91.83  ? 94  TYR L CD2 1 
ATOM 4594 C CE1 . TYR E 3 94  ? 270.534 300.617 423.297 1.00 91.83  ? 94  TYR L CE1 1 
ATOM 4595 C CE2 . TYR E 3 94  ? 269.254 298.800 422.414 1.00 91.83  ? 94  TYR L CE2 1 
ATOM 4596 C CZ  . TYR E 3 94  ? 269.950 299.378 423.451 1.00 91.83  ? 94  TYR L CZ  1 
ATOM 4597 O OH  . TYR E 3 94  ? 270.063 298.710 424.647 1.00 91.83  ? 94  TYR L OH  1 
ATOM 4598 N N   . CYS E 3 95  ? 269.424 304.282 418.420 1.00 91.07  ? 95  CYS L N   1 
ATOM 4599 C CA  . CYS E 3 95  ? 269.793 305.013 417.219 1.00 91.07  ? 95  CYS L CA  1 
ATOM 4600 C C   . CYS E 3 95  ? 271.307 305.090 417.140 1.00 91.07  ? 95  CYS L C   1 
ATOM 4601 O O   . CYS E 3 95  ? 271.980 305.209 418.166 1.00 91.07  ? 95  CYS L O   1 
ATOM 4602 C CB  . CYS E 3 95  ? 269.177 306.422 417.175 1.00 91.07  ? 95  CYS L CB  1 
ATOM 4603 S SG  . CYS E 3 95  ? 269.737 307.609 418.418 1.00 91.07  ? 95  CYS L SG  1 
ATOM 4604 N N   . GLN E 3 96  ? 271.841 305.001 415.928 1.00 83.18  ? 96  GLN L N   1 
ATOM 4605 C CA  . GLN E 3 96  ? 273.279 305.069 415.734 1.00 83.18  ? 96  GLN L CA  1 
ATOM 4606 C C   . GLN E 3 96  ? 273.650 306.221 414.812 1.00 83.18  ? 96  GLN L C   1 
ATOM 4607 O O   . GLN E 3 96  ? 272.803 306.945 414.290 1.00 83.18  ? 96  GLN L O   1 
ATOM 4608 C CB  . GLN E 3 96  ? 273.841 303.775 415.159 1.00 83.18  ? 96  GLN L CB  1 
ATOM 4609 C CG  . GLN E 3 96  ? 273.390 303.482 413.777 1.00 83.18  ? 96  GLN L CG  1 
ATOM 4610 C CD  . GLN E 3 96  ? 274.137 302.327 413.179 1.00 83.18  ? 96  GLN L CD  1 
ATOM 4611 O OE1 . GLN E 3 96  ? 275.164 301.900 413.694 1.00 83.18  ? 96  GLN L OE1 1 
ATOM 4612 N NE2 . GLN E 3 96  ? 273.595 301.776 412.115 1.00 83.18  ? 96  GLN L NE2 1 
ATOM 4613 N N   . GLN E 3 97  ? 274.954 306.348 414.607 1.00 82.44  ? 97  GLN L N   1 
ATOM 4614 C CA  . GLN E 3 97  ? 275.575 307.474 413.931 1.00 82.44  ? 97  GLN L CA  1 
ATOM 4615 C C   . GLN E 3 97  ? 276.593 306.910 412.956 1.00 82.44  ? 97  GLN L C   1 
ATOM 4616 O O   . GLN E 3 97  ? 277.398 306.055 413.329 1.00 82.44  ? 97  GLN L O   1 
ATOM 4617 C CB  . GLN E 3 97  ? 276.224 308.403 414.958 1.00 82.44  ? 97  GLN L CB  1 
ATOM 4618 C CG  . GLN E 3 97  ? 276.869 309.642 414.423 1.00 82.44  ? 97  GLN L CG  1 
ATOM 4619 C CD  . GLN E 3 97  ? 278.330 309.435 414.127 1.00 82.44  ? 97  GLN L CD  1 
ATOM 4620 O OE1 . GLN E 3 97  ? 278.991 308.606 414.742 1.00 82.44  ? 97  GLN L OE1 1 
ATOM 4621 N NE2 . GLN E 3 97  ? 278.842 310.189 413.180 1.00 82.44  ? 97  GLN L NE2 1 
ATOM 4622 N N   . ASN E 3 98  ? 276.553 307.375 411.715 1.00 76.72  ? 98  ASN L N   1 
ATOM 4623 C CA  . ASN E 3 98  ? 277.310 306.750 410.642 1.00 76.72  ? 98  ASN L CA  1 
ATOM 4624 C C   . ASN E 3 98  ? 278.309 307.703 409.992 1.00 76.72  ? 98  ASN L C   1 
ATOM 4625 O O   . ASN E 3 98  ? 279.066 307.285 409.113 1.00 76.72  ? 98  ASN L O   1 
ATOM 4626 C CB  . ASN E 3 98  ? 276.332 306.221 409.589 1.00 76.72  ? 98  ASN L CB  1 
ATOM 4627 C CG  . ASN E 3 98  ? 276.910 305.132 408.749 1.00 76.72  ? 98  ASN L CG  1 
ATOM 4628 O OD1 . ASN E 3 98  ? 277.999 304.649 409.017 1.00 76.72  ? 98  ASN L OD1 1 
ATOM 4629 N ND2 . ASN E 3 98  ? 276.197 304.755 407.698 1.00 76.72  ? 98  ASN L ND2 1 
ATOM 4630 N N   . ASN E 3 99  ? 278.344 308.963 410.419 1.00 79.27  ? 99  ASN L N   1 
ATOM 4631 C CA  . ASN E 3 99  ? 279.109 309.977 409.706 1.00 79.27  ? 99  ASN L CA  1 
ATOM 4632 C C   . ASN E 3 99  ? 280.599 309.885 410.020 1.00 79.27  ? 99  ASN L C   1 
ATOM 4633 O O   . ASN E 3 99  ? 281.436 310.230 409.179 1.00 79.27  ? 99  ASN L O   1 
ATOM 4634 C CB  . ASN E 3 99  ? 278.560 311.358 410.060 1.00 79.27  ? 99  ASN L CB  1 
ATOM 4635 C CG  . ASN E 3 99  ? 278.974 312.431 409.082 1.00 79.27  ? 99  ASN L CG  1 
ATOM 4636 O OD1 . ASN E 3 99  ? 279.657 312.168 408.096 1.00 79.27  ? 99  ASN L OD1 1 
ATOM 4637 N ND2 . ASN E 3 99  ? 278.550 313.658 409.348 1.00 79.27  ? 99  ASN L ND2 1 
ATOM 4638 N N   . GLU E 3 100 ? 280.955 309.409 411.206 1.00 82.42  ? 100 GLU L N   1 
ATOM 4639 C CA  . GLU E 3 100 ? 282.329 309.439 411.679 1.00 82.42  ? 100 GLU L CA  1 
ATOM 4640 C C   . GLU E 3 100 ? 282.810 308.011 411.939 1.00 82.42  ? 100 GLU L C   1 
ATOM 4641 O O   . GLU E 3 100 ? 282.019 307.072 412.032 1.00 82.42  ? 100 GLU L O   1 
ATOM 4642 C CB  . GLU E 3 100 ? 282.421 310.306 412.945 1.00 82.42  ? 100 GLU L CB  1 
ATOM 4643 C CG  . GLU E 3 100 ? 283.808 310.843 413.293 1.00 82.42  ? 100 GLU L CG  1 
ATOM 4644 C CD  . GLU E 3 100 ? 283.840 311.553 414.626 1.00 82.42  ? 100 GLU L CD  1 
ATOM 4645 O OE1 . GLU E 3 100 ? 282.798 311.578 415.309 1.00 82.42  ? 100 GLU L OE1 1 
ATOM 4646 O OE2 . GLU E 3 100 ? 284.911 312.077 414.997 1.00 82.42  ? 100 GLU L OE2 1 
ATOM 4647 N N   . VAL E 3 101 ? 284.127 307.857 412.041 1.00 81.45  ? 101 VAL L N   1 
ATOM 4648 C CA  . VAL E 3 101 ? 284.802 306.574 412.257 1.00 81.45  ? 101 VAL L CA  1 
ATOM 4649 C C   . VAL E 3 101 ? 284.415 305.853 413.557 1.00 81.45  ? 101 VAL L C   1 
ATOM 4650 O O   . VAL E 3 101 ? 284.137 304.648 413.470 1.00 81.45  ? 101 VAL L O   1 
ATOM 4651 C CB  . VAL E 3 101 ? 286.330 306.759 412.155 1.00 81.45  ? 101 VAL L CB  1 
ATOM 4652 C CG1 . VAL E 3 101 ? 287.063 305.438 412.329 1.00 81.45  ? 101 VAL L CG1 1 
ATOM 4653 C CG2 . VAL E 3 101 ? 286.701 307.416 410.841 1.00 81.45  ? 101 VAL L CG2 1 
ATOM 4654 N N   . PRO E 3 102 ? 284.367 306.468 414.760 1.00 82.43  ? 102 PRO L N   1 
ATOM 4655 C CA  . PRO E 3 102 ? 284.130 305.650 415.969 1.00 82.43  ? 102 PRO L CA  1 
ATOM 4656 C C   . PRO E 3 102 ? 282.737 305.050 416.103 1.00 82.43  ? 102 PRO L C   1 
ATOM 4657 O O   . PRO E 3 102 ? 282.585 304.143 416.931 1.00 82.43  ? 102 PRO L O   1 
ATOM 4658 C CB  . PRO E 3 102 ? 284.397 306.626 417.120 1.00 82.43  ? 102 PRO L CB  1 
ATOM 4659 C CG  . PRO E 3 102 ? 285.239 307.651 416.559 1.00 82.43  ? 102 PRO L CG  1 
ATOM 4660 C CD  . PRO E 3 102 ? 284.734 307.838 415.179 1.00 82.43  ? 102 PRO L CD  1 
ATOM 4661 N N   . LEU E 3 103 ? 281.738 305.536 415.359 1.00 81.35  ? 103 LEU L N   1 
ATOM 4662 C CA  . LEU E 3 103 ? 280.401 304.937 415.238 1.00 81.35  ? 103 LEU L CA  1 
ATOM 4663 C C   . LEU E 3 103 ? 279.701 304.830 416.598 1.00 81.35  ? 103 LEU L C   1 
ATOM 4664 O O   . LEU E 3 103 ? 279.400 303.746 417.094 1.00 81.35  ? 103 LEU L O   1 
ATOM 4665 C CB  . LEU E 3 103 ? 280.479 303.565 414.558 1.00 81.35  ? 103 LEU L CB  1 
ATOM 4666 C CG  . LEU E 3 103 ? 280.978 303.535 413.116 1.00 81.35  ? 103 LEU L CG  1 
ATOM 4667 C CD1 . LEU E 3 103 ? 281.164 302.109 412.661 1.00 81.35  ? 103 LEU L CD1 1 
ATOM 4668 C CD2 . LEU E 3 103 ? 280.007 304.254 412.208 1.00 81.35  ? 103 LEU L CD2 1 
ATOM 4669 N N   . THR E 3 104 ? 279.465 305.992 417.195 1.00 86.47  ? 104 THR L N   1 
ATOM 4670 C CA  . THR E 3 104 ? 278.840 306.044 418.508 1.00 86.47  ? 104 THR L CA  1 
ATOM 4671 C C   . THR E 3 104 ? 277.353 305.750 418.399 1.00 86.47  ? 104 THR L C   1 
ATOM 4672 O O   . THR E 3 104 ? 276.707 306.109 417.411 1.00 86.47  ? 104 THR L O   1 
ATOM 4673 C CB  . THR E 3 104 ? 279.047 307.414 419.140 1.00 86.47  ? 104 THR L CB  1 
ATOM 4674 O OG1 . THR E 3 104 ? 278.399 308.400 418.333 1.00 86.47  ? 104 THR L OG1 1 
ATOM 4675 C CG2 . THR E 3 104 ? 280.522 307.734 419.213 1.00 86.47  ? 104 THR L CG2 1 
ATOM 4676 N N   . PHE E 3 105 ? 276.812 305.084 419.413 1.00 86.75  ? 105 PHE L N   1 
ATOM 4677 C CA  . PHE E 3 105 ? 275.421 304.656 419.383 1.00 86.75  ? 105 PHE L CA  1 
ATOM 4678 C C   . PHE E 3 105 ? 274.596 305.449 420.389 1.00 86.75  ? 105 PHE L C   1 
ATOM 4679 O O   . PHE E 3 105 ? 275.071 306.391 421.025 1.00 86.75  ? 105 PHE L O   1 
ATOM 4680 C CB  . PHE E 3 105 ? 275.273 303.158 419.679 1.00 86.75  ? 105 PHE L CB  1 
ATOM 4681 C CG  . PHE E 3 105 ? 275.800 302.235 418.596 1.00 86.75  ? 105 PHE L CG  1 
ATOM 4682 C CD1 . PHE E 3 105 ? 276.309 302.705 417.405 1.00 86.75  ? 105 PHE L CD1 1 
ATOM 4683 C CD2 . PHE E 3 105 ? 275.717 300.874 418.769 1.00 86.75  ? 105 PHE L CD2 1 
ATOM 4684 C CE1 . PHE E 3 105 ? 276.770 301.835 416.442 1.00 86.75  ? 105 PHE L CE1 1 
ATOM 4685 C CE2 . PHE E 3 105 ? 276.163 300.002 417.812 1.00 86.75  ? 105 PHE L CE2 1 
ATOM 4686 C CZ  . PHE E 3 105 ? 276.690 300.483 416.651 1.00 86.75  ? 105 PHE L CZ  1 
ATOM 4687 N N   . GLY E 3 106 ? 273.333 305.046 420.530 1.00 92.63  ? 106 GLY L N   1 
ATOM 4688 C CA  . GLY E 3 106 ? 272.439 305.688 421.468 1.00 92.63  ? 106 GLY L CA  1 
ATOM 4689 C C   . GLY E 3 106 ? 272.249 304.886 422.743 1.00 92.63  ? 106 GLY L C   1 
ATOM 4690 O O   . GLY E 3 106 ? 272.697 303.749 422.868 1.00 92.63  ? 106 GLY L O   1 
ATOM 4691 N N   . ALA E 3 107 ? 271.569 305.508 423.707 1.00 95.22  ? 107 ALA L N   1 
ATOM 4692 C CA  . ALA E 3 107 ? 271.309 304.849 424.981 1.00 95.22  ? 107 ALA L CA  1 
ATOM 4693 C C   . ALA E 3 107 ? 270.091 303.939 424.916 1.00 95.22  ? 107 ALA L C   1 
ATOM 4694 O O   . ALA E 3 107 ? 270.050 302.918 425.609 1.00 95.22  ? 107 ALA L O   1 
ATOM 4695 C CB  . ALA E 3 107 ? 271.129 305.889 426.085 1.00 95.22  ? 107 ALA L CB  1 
ATOM 4696 N N   . GLY E 3 108 ? 269.102 304.289 424.113 1.00 99.38  ? 108 GLY L N   1 
ATOM 4697 C CA  . GLY E 3 108 ? 267.927 303.464 423.934 1.00 99.38  ? 108 GLY L CA  1 
ATOM 4698 C C   . GLY E 3 108 ? 266.867 303.728 424.985 1.00 99.38  ? 108 GLY L C   1 
ATOM 4699 O O   . GLY E 3 108 ? 267.160 304.059 426.138 1.00 99.38  ? 108 GLY L O   1 
ATOM 4700 N N   . THR E 3 109 ? 265.608 303.588 424.580 1.00 102.09 ? 109 THR L N   1 
ATOM 4701 C CA  . THR E 3 109 ? 264.469 303.694 425.478 1.00 102.09 ? 109 THR L CA  1 
ATOM 4702 C C   . THR E 3 109 ? 263.778 302.342 425.564 1.00 102.09 ? 109 THR L C   1 
ATOM 4703 O O   . THR E 3 109 ? 264.251 301.349 425.014 1.00 102.09 ? 109 THR L O   1 
ATOM 4704 C CB  . THR E 3 109 ? 263.468 304.750 425.004 1.00 102.09 ? 109 THR L CB  1 
ATOM 4705 O OG1 . THR E 3 109 ? 262.838 304.299 423.802 1.00 102.09 ? 109 THR L OG1 1 
ATOM 4706 C CG2 . THR E 3 109 ? 264.182 306.058 424.732 1.00 102.09 ? 109 THR L CG2 1 
ATOM 4707 N N   . LYS E 3 110 ? 262.649 302.309 426.268 1.00 103.28 ? 110 LYS L N   1 
ATOM 4708 C CA  . LYS E 3 110 ? 261.843 301.105 426.396 1.00 103.28 ? 110 LYS L CA  1 
ATOM 4709 C C   . LYS E 3 110 ? 260.371 301.458 426.244 1.00 103.28 ? 110 LYS L C   1 
ATOM 4710 O O   . LYS E 3 110 ? 259.986 302.629 426.268 1.00 103.28 ? 110 LYS L O   1 
ATOM 4711 C CB  . LYS E 3 110 ? 262.069 300.406 427.745 1.00 103.28 ? 110 LYS L CB  1 
ATOM 4712 C CG  . LYS E 3 110 ? 263.440 299.772 427.903 1.00 103.28 ? 110 LYS L CG  1 
ATOM 4713 C CD  . LYS E 3 110 ? 263.584 299.064 429.235 1.00 103.28 ? 110 LYS L CD  1 
ATOM 4714 C CE  . LYS E 3 110 ? 264.965 298.446 429.377 1.00 103.28 ? 110 LYS L CE  1 
ATOM 4715 N NZ  . LYS E 3 110 ? 265.124 297.744 430.680 1.00 103.28 ? 110 LYS L NZ  1 
ATOM 4716 N N   . LEU E 3 111 ? 259.548 300.426 426.083 1.00 103.77 ? 111 LEU L N   1 
ATOM 4717 C CA  . LEU E 3 111 ? 258.100 300.604 426.049 1.00 103.77 ? 111 LEU L CA  1 
ATOM 4718 C C   . LEU E 3 111 ? 257.395 299.657 427.017 1.00 103.77 ? 111 LEU L C   1 
ATOM 4719 O O   . LEU E 3 111 ? 256.296 299.945 427.496 1.00 103.77 ? 111 LEU L O   1 
ATOM 4720 C CB  . LEU E 3 111 ? 257.556 300.400 424.637 1.00 103.77 ? 111 LEU L CB  1 
ATOM 4721 C CG  . LEU E 3 111 ? 257.948 301.429 423.580 1.00 103.77 ? 111 LEU L CG  1 
ATOM 4722 C CD1 . LEU E 3 111 ? 257.351 301.043 422.243 1.00 103.77 ? 111 LEU L CD1 1 
ATOM 4723 C CD2 . LEU E 3 111 ? 257.503 302.817 423.984 1.00 103.77 ? 111 LEU L CD2 1 
# 
