data_8W5G
# 
_entry.id   8W5G 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8W5G         pdb_00008w5g 10.2210/pdb8w5g/pdb 
WWPDB D_1300040593 ?            ?                   
EMDB  EMD-37291    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-02-26 ? 
2 'EM metadata'     1 0 2025-02-26 ? 
3 'Half map'        1 0 2025-02-26 1 
4 'Half map'        1 0 2025-02-26 2 
5 Image             1 0 2025-02-26 ? 
6 'Primary map'     1 0 2025-02-26 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Half map'        repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 Image             repository 'Initial release' ? ? 
6 6 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8W5G 
_pdbx_database_status.recvd_initial_deposition_date   2023-08-26 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure of Qb-Ab7' 
_pdbx_database_related.db_id          EMD-37291 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              zhup@ibp.ac.cn 
_pdbx_contact_author.name_first         Ping 
_pdbx_contact_author.name_last          Zhu 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-2648-3170 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Bao, K.Y.' 1 ? 
'Li, R.H.'  2 ? 
'Hua, Z.L.' 3 ? 
'Hou, B.D.' 4 ? 
'Zhu, P.'   5 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Cell Rep' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2211-1247 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            44 
_citation.language                  ? 
_citation.page_first                115334 
_citation.page_last                 115334 
_citation.title                     
'Competition propels, rather than limits, the success of low-affinity B cells in the germinal center response.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.celrep.2025.115334 
_citation.pdbx_database_id_PubMed   39955776 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Li, R.'  1 ? 
primary 'Bao, K.' 2 ? 
primary 'Liu, C.' 3 ? 
primary 'Ma, X.'  4 ? 
primary 'Hua, Z.' 5 ? 
primary 'Zhu, P.' 6 ? 
primary 'Hou, B.' 7 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'Minor capsid protein A1' 14136.874 3 ? ? ? ? 
2 polymer man 'Light chain of Ab7'      10956.034 1 ? ? ? ? 
3 polymer man 'Heavy chain of Ab7'      10200.267 1 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'A1 read-through protein' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;AKLETVTLGNIGKDGKQTLVLNPRGVNPTNGVASLSQAGAVPALEKRVTVSVSQPSRNRKNYKVQVKIQNPTACTANGSC
DPSVTRQAYADVTFSFTQYSTDEERAFVRTELAALLASPLLIDAIDQLNPAY
;
;AKLETVTLGNIGKDGKQTLVLNPRGVNPTNGVASLSQAGAVPALEKRVTVSVSQPSRNRKNYKVQVKIQNPTACTANGSC
DPSVTRQAYADVTFSFTQYSTDEERAFVRTELAALLASPLLIDAIDQLNPAY
;
A,B,C ? 
2 'polypeptide(L)' no no 
;IQMTQSPSSLSASLGERVSLTCRASQDIGSSLNWLQQKPDGTIKRLIYATSNLDSGVPKRFSGSRSGSDYSLTISSLETE
DFVDYYCLQYATSPYTFGGGT
;
;IQMTQSPSSLSASLGERVSLTCRASQDIGSSLNWLQQKPDGTIKRLIYATSNLDSGVPKRFSGSRSGSDYSLTISSLETE
DFVDYYCLQYATSPYTFGGGT
;
L     ? 
3 'polypeptide(L)' no no 
;ISCKSSGYAFSSSWMNWVKQRPGKGLEWIGRIYPENGETNYNGKFKGKATLTADKSSRSAYMQLNSLTSEDSAVYFCARS
GYYFSSNYDF
;
;ISCKSSGYAFSSSWMNWVKQRPGKGLEWIGRIYPENGETNYNGKFKGKATLTADKSSRSAYMQLNSLTSEDSAVYFCARS
GYYFSSNYDF
;
H     ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   ALA n 
1 2   LYS n 
1 3   LEU n 
1 4   GLU n 
1 5   THR n 
1 6   VAL n 
1 7   THR n 
1 8   LEU n 
1 9   GLY n 
1 10  ASN n 
1 11  ILE n 
1 12  GLY n 
1 13  LYS n 
1 14  ASP n 
1 15  GLY n 
1 16  LYS n 
1 17  GLN n 
1 18  THR n 
1 19  LEU n 
1 20  VAL n 
1 21  LEU n 
1 22  ASN n 
1 23  PRO n 
1 24  ARG n 
1 25  GLY n 
1 26  VAL n 
1 27  ASN n 
1 28  PRO n 
1 29  THR n 
1 30  ASN n 
1 31  GLY n 
1 32  VAL n 
1 33  ALA n 
1 34  SER n 
1 35  LEU n 
1 36  SER n 
1 37  GLN n 
1 38  ALA n 
1 39  GLY n 
1 40  ALA n 
1 41  VAL n 
1 42  PRO n 
1 43  ALA n 
1 44  LEU n 
1 45  GLU n 
1 46  LYS n 
1 47  ARG n 
1 48  VAL n 
1 49  THR n 
1 50  VAL n 
1 51  SER n 
1 52  VAL n 
1 53  SER n 
1 54  GLN n 
1 55  PRO n 
1 56  SER n 
1 57  ARG n 
1 58  ASN n 
1 59  ARG n 
1 60  LYS n 
1 61  ASN n 
1 62  TYR n 
1 63  LYS n 
1 64  VAL n 
1 65  GLN n 
1 66  VAL n 
1 67  LYS n 
1 68  ILE n 
1 69  GLN n 
1 70  ASN n 
1 71  PRO n 
1 72  THR n 
1 73  ALA n 
1 74  CYS n 
1 75  THR n 
1 76  ALA n 
1 77  ASN n 
1 78  GLY n 
1 79  SER n 
1 80  CYS n 
1 81  ASP n 
1 82  PRO n 
1 83  SER n 
1 84  VAL n 
1 85  THR n 
1 86  ARG n 
1 87  GLN n 
1 88  ALA n 
1 89  TYR n 
1 90  ALA n 
1 91  ASP n 
1 92  VAL n 
1 93  THR n 
1 94  PHE n 
1 95  SER n 
1 96  PHE n 
1 97  THR n 
1 98  GLN n 
1 99  TYR n 
1 100 SER n 
1 101 THR n 
1 102 ASP n 
1 103 GLU n 
1 104 GLU n 
1 105 ARG n 
1 106 ALA n 
1 107 PHE n 
1 108 VAL n 
1 109 ARG n 
1 110 THR n 
1 111 GLU n 
1 112 LEU n 
1 113 ALA n 
1 114 ALA n 
1 115 LEU n 
1 116 LEU n 
1 117 ALA n 
1 118 SER n 
1 119 PRO n 
1 120 LEU n 
1 121 LEU n 
1 122 ILE n 
1 123 ASP n 
1 124 ALA n 
1 125 ILE n 
1 126 ASP n 
1 127 GLN n 
1 128 LEU n 
1 129 ASN n 
1 130 PRO n 
1 131 ALA n 
1 132 TYR n 
2 1   ILE n 
2 2   GLN n 
2 3   MET n 
2 4   THR n 
2 5   GLN n 
2 6   SER n 
2 7   PRO n 
2 8   SER n 
2 9   SER n 
2 10  LEU n 
2 11  SER n 
2 12  ALA n 
2 13  SER n 
2 14  LEU n 
2 15  GLY n 
2 16  GLU n 
2 17  ARG n 
2 18  VAL n 
2 19  SER n 
2 20  LEU n 
2 21  THR n 
2 22  CYS n 
2 23  ARG n 
2 24  ALA n 
2 25  SER n 
2 26  GLN n 
2 27  ASP n 
2 28  ILE n 
2 29  GLY n 
2 30  SER n 
2 31  SER n 
2 32  LEU n 
2 33  ASN n 
2 34  TRP n 
2 35  LEU n 
2 36  GLN n 
2 37  GLN n 
2 38  LYS n 
2 39  PRO n 
2 40  ASP n 
2 41  GLY n 
2 42  THR n 
2 43  ILE n 
2 44  LYS n 
2 45  ARG n 
2 46  LEU n 
2 47  ILE n 
2 48  TYR n 
2 49  ALA n 
2 50  THR n 
2 51  SER n 
2 52  ASN n 
2 53  LEU n 
2 54  ASP n 
2 55  SER n 
2 56  GLY n 
2 57  VAL n 
2 58  PRO n 
2 59  LYS n 
2 60  ARG n 
2 61  PHE n 
2 62  SER n 
2 63  GLY n 
2 64  SER n 
2 65  ARG n 
2 66  SER n 
2 67  GLY n 
2 68  SER n 
2 69  ASP n 
2 70  TYR n 
2 71  SER n 
2 72  LEU n 
2 73  THR n 
2 74  ILE n 
2 75  SER n 
2 76  SER n 
2 77  LEU n 
2 78  GLU n 
2 79  THR n 
2 80  GLU n 
2 81  ASP n 
2 82  PHE n 
2 83  VAL n 
2 84  ASP n 
2 85  TYR n 
2 86  TYR n 
2 87  CYS n 
2 88  LEU n 
2 89  GLN n 
2 90  TYR n 
2 91  ALA n 
2 92  THR n 
2 93  SER n 
2 94  PRO n 
2 95  TYR n 
2 96  THR n 
2 97  PHE n 
2 98  GLY n 
2 99  GLY n 
2 100 GLY n 
2 101 THR n 
3 1   ILE n 
3 2   SER n 
3 3   CYS n 
3 4   LYS n 
3 5   SER n 
3 6   SER n 
3 7   GLY n 
3 8   TYR n 
3 9   ALA n 
3 10  PHE n 
3 11  SER n 
3 12  SER n 
3 13  SER n 
3 14  TRP n 
3 15  MET n 
3 16  ASN n 
3 17  TRP n 
3 18  VAL n 
3 19  LYS n 
3 20  GLN n 
3 21  ARG n 
3 22  PRO n 
3 23  GLY n 
3 24  LYS n 
3 25  GLY n 
3 26  LEU n 
3 27  GLU n 
3 28  TRP n 
3 29  ILE n 
3 30  GLY n 
3 31  ARG n 
3 32  ILE n 
3 33  TYR n 
3 34  PRO n 
3 35  GLU n 
3 36  ASN n 
3 37  GLY n 
3 38  GLU n 
3 39  THR n 
3 40  ASN n 
3 41  TYR n 
3 42  ASN n 
3 43  GLY n 
3 44  LYS n 
3 45  PHE n 
3 46  LYS n 
3 47  GLY n 
3 48  LYS n 
3 49  ALA n 
3 50  THR n 
3 51  LEU n 
3 52  THR n 
3 53  ALA n 
3 54  ASP n 
3 55  LYS n 
3 56  SER n 
3 57  SER n 
3 58  ARG n 
3 59  SER n 
3 60  ALA n 
3 61  TYR n 
3 62  MET n 
3 63  GLN n 
3 64  LEU n 
3 65  ASN n 
3 66  SER n 
3 67  LEU n 
3 68  THR n 
3 69  SER n 
3 70  GLU n 
3 71  ASP n 
3 72  SER n 
3 73  ALA n 
3 74  VAL n 
3 75  TYR n 
3 76  PHE n 
3 77  CYS n 
3 78  ALA n 
3 79  ARG n 
3 80  SER n 
3 81  GLY n 
3 82  TYR n 
3 83  TYR n 
3 84  PHE n 
3 85  SER n 
3 86  SER n 
3 87  ASN n 
3 88  TYR n 
3 89  ASP n 
3 90  PHE n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 132 ? ? ? ? ? ? ? ? ? 'Escherichia phage Qbeta' 2789016 ? ? ? ? ? ? ? ? 'Escherichia coli' 562  
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 101 ? ? ? ? ? ? ? ? ? 'Mus musculus'            10090   ? ? ? ? ? ? ? ? 'Homo sapiens'     9606 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 90  ? ? ? ? ? ? ? ? ? 'Mus musculus'            10090   ? ? ? ? ? ? ? ? 'Homo sapiens'     9606 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   ALA 1   1   1   ALA ALA A . n 
A 1 2   LYS 2   2   2   LYS LYS A . n 
A 1 3   LEU 3   3   3   LEU LEU A . n 
A 1 4   GLU 4   4   4   GLU GLU A . n 
A 1 5   THR 5   5   5   THR THR A . n 
A 1 6   VAL 6   6   6   VAL VAL A . n 
A 1 7   THR 7   7   7   THR THR A . n 
A 1 8   LEU 8   8   8   LEU LEU A . n 
A 1 9   GLY 9   9   9   GLY GLY A . n 
A 1 10  ASN 10  10  10  ASN ASN A . n 
A 1 11  ILE 11  11  11  ILE ILE A . n 
A 1 12  GLY 12  12  12  GLY GLY A . n 
A 1 13  LYS 13  13  13  LYS LYS A . n 
A 1 14  ASP 14  14  14  ASP ASP A . n 
A 1 15  GLY 15  15  15  GLY GLY A . n 
A 1 16  LYS 16  16  16  LYS LYS A . n 
A 1 17  GLN 17  17  17  GLN GLN A . n 
A 1 18  THR 18  18  18  THR THR A . n 
A 1 19  LEU 19  19  19  LEU LEU A . n 
A 1 20  VAL 20  20  20  VAL VAL A . n 
A 1 21  LEU 21  21  21  LEU LEU A . n 
A 1 22  ASN 22  22  22  ASN ASN A . n 
A 1 23  PRO 23  23  23  PRO PRO A . n 
A 1 24  ARG 24  24  24  ARG ARG A . n 
A 1 25  GLY 25  25  25  GLY GLY A . n 
A 1 26  VAL 26  26  26  VAL VAL A . n 
A 1 27  ASN 27  27  27  ASN ASN A . n 
A 1 28  PRO 28  28  28  PRO PRO A . n 
A 1 29  THR 29  29  29  THR THR A . n 
A 1 30  ASN 30  30  30  ASN ASN A . n 
A 1 31  GLY 31  31  31  GLY GLY A . n 
A 1 32  VAL 32  32  32  VAL VAL A . n 
A 1 33  ALA 33  33  33  ALA ALA A . n 
A 1 34  SER 34  34  34  SER SER A . n 
A 1 35  LEU 35  35  35  LEU LEU A . n 
A 1 36  SER 36  36  36  SER SER A . n 
A 1 37  GLN 37  37  37  GLN GLN A . n 
A 1 38  ALA 38  38  38  ALA ALA A . n 
A 1 39  GLY 39  39  39  GLY GLY A . n 
A 1 40  ALA 40  40  40  ALA ALA A . n 
A 1 41  VAL 41  41  41  VAL VAL A . n 
A 1 42  PRO 42  42  42  PRO PRO A . n 
A 1 43  ALA 43  43  43  ALA ALA A . n 
A 1 44  LEU 44  44  44  LEU LEU A . n 
A 1 45  GLU 45  45  45  GLU GLU A . n 
A 1 46  LYS 46  46  46  LYS LYS A . n 
A 1 47  ARG 47  47  47  ARG ARG A . n 
A 1 48  VAL 48  48  48  VAL VAL A . n 
A 1 49  THR 49  49  49  THR THR A . n 
A 1 50  VAL 50  50  50  VAL VAL A . n 
A 1 51  SER 51  51  51  SER SER A . n 
A 1 52  VAL 52  52  52  VAL VAL A . n 
A 1 53  SER 53  53  53  SER SER A . n 
A 1 54  GLN 54  54  54  GLN GLN A . n 
A 1 55  PRO 55  55  55  PRO PRO A . n 
A 1 56  SER 56  56  56  SER SER A . n 
A 1 57  ARG 57  57  57  ARG ARG A . n 
A 1 58  ASN 58  58  58  ASN ASN A . n 
A 1 59  ARG 59  59  59  ARG ARG A . n 
A 1 60  LYS 60  60  60  LYS LYS A . n 
A 1 61  ASN 61  61  61  ASN ASN A . n 
A 1 62  TYR 62  62  62  TYR TYR A . n 
A 1 63  LYS 63  63  63  LYS LYS A . n 
A 1 64  VAL 64  64  64  VAL VAL A . n 
A 1 65  GLN 65  65  65  GLN GLN A . n 
A 1 66  VAL 66  66  66  VAL VAL A . n 
A 1 67  LYS 67  67  67  LYS LYS A . n 
A 1 68  ILE 68  68  68  ILE ILE A . n 
A 1 69  GLN 69  69  69  GLN GLN A . n 
A 1 70  ASN 70  70  70  ASN ASN A . n 
A 1 71  PRO 71  71  71  PRO PRO A . n 
A 1 72  THR 72  72  72  THR THR A . n 
A 1 73  ALA 73  73  73  ALA ALA A . n 
A 1 74  CYS 74  74  74  CYS CYS A . n 
A 1 75  THR 75  75  75  THR THR A . n 
A 1 76  ALA 76  76  76  ALA ALA A . n 
A 1 77  ASN 77  77  77  ASN ASN A . n 
A 1 78  GLY 78  78  78  GLY GLY A . n 
A 1 79  SER 79  79  79  SER SER A . n 
A 1 80  CYS 80  80  80  CYS CYS A . n 
A 1 81  ASP 81  81  81  ASP ASP A . n 
A 1 82  PRO 82  82  82  PRO PRO A . n 
A 1 83  SER 83  83  83  SER SER A . n 
A 1 84  VAL 84  84  84  VAL VAL A . n 
A 1 85  THR 85  85  85  THR THR A . n 
A 1 86  ARG 86  86  86  ARG ARG A . n 
A 1 87  GLN 87  87  87  GLN GLN A . n 
A 1 88  ALA 88  88  88  ALA ALA A . n 
A 1 89  TYR 89  89  89  TYR TYR A . n 
A 1 90  ALA 90  90  90  ALA ALA A . n 
A 1 91  ASP 91  91  91  ASP ASP A . n 
A 1 92  VAL 92  92  92  VAL VAL A . n 
A 1 93  THR 93  93  93  THR THR A . n 
A 1 94  PHE 94  94  94  PHE PHE A . n 
A 1 95  SER 95  95  95  SER SER A . n 
A 1 96  PHE 96  96  96  PHE PHE A . n 
A 1 97  THR 97  97  97  THR THR A . n 
A 1 98  GLN 98  98  98  GLN GLN A . n 
A 1 99  TYR 99  99  99  TYR TYR A . n 
A 1 100 SER 100 100 100 SER SER A . n 
A 1 101 THR 101 101 101 THR THR A . n 
A 1 102 ASP 102 102 102 ASP ASP A . n 
A 1 103 GLU 103 103 103 GLU GLU A . n 
A 1 104 GLU 104 104 104 GLU GLU A . n 
A 1 105 ARG 105 105 105 ARG ARG A . n 
A 1 106 ALA 106 106 106 ALA ALA A . n 
A 1 107 PHE 107 107 107 PHE PHE A . n 
A 1 108 VAL 108 108 108 VAL VAL A . n 
A 1 109 ARG 109 109 109 ARG ARG A . n 
A 1 110 THR 110 110 110 THR THR A . n 
A 1 111 GLU 111 111 111 GLU GLU A . n 
A 1 112 LEU 112 112 112 LEU LEU A . n 
A 1 113 ALA 113 113 113 ALA ALA A . n 
A 1 114 ALA 114 114 114 ALA ALA A . n 
A 1 115 LEU 115 115 115 LEU LEU A . n 
A 1 116 LEU 116 116 116 LEU LEU A . n 
A 1 117 ALA 117 117 117 ALA ALA A . n 
A 1 118 SER 118 118 118 SER SER A . n 
A 1 119 PRO 119 119 119 PRO PRO A . n 
A 1 120 LEU 120 120 120 LEU LEU A . n 
A 1 121 LEU 121 121 121 LEU LEU A . n 
A 1 122 ILE 122 122 122 ILE ILE A . n 
A 1 123 ASP 123 123 123 ASP ASP A . n 
A 1 124 ALA 124 124 124 ALA ALA A . n 
A 1 125 ILE 125 125 125 ILE ILE A . n 
A 1 126 ASP 126 126 126 ASP ASP A . n 
A 1 127 GLN 127 127 127 GLN GLN A . n 
A 1 128 LEU 128 128 128 LEU LEU A . n 
A 1 129 ASN 129 129 129 ASN ASN A . n 
A 1 130 PRO 130 130 130 PRO PRO A . n 
A 1 131 ALA 131 131 131 ALA ALA A . n 
A 1 132 TYR 132 132 ?   ?   ?   A . n 
B 1 1   ALA 1   1   1   ALA ALA B . n 
B 1 2   LYS 2   2   2   LYS LYS B . n 
B 1 3   LEU 3   3   3   LEU LEU B . n 
B 1 4   GLU 4   4   4   GLU GLU B . n 
B 1 5   THR 5   5   5   THR THR B . n 
B 1 6   VAL 6   6   6   VAL VAL B . n 
B 1 7   THR 7   7   7   THR THR B . n 
B 1 8   LEU 8   8   8   LEU LEU B . n 
B 1 9   GLY 9   9   9   GLY GLY B . n 
B 1 10  ASN 10  10  10  ASN ASN B . n 
B 1 11  ILE 11  11  11  ILE ILE B . n 
B 1 12  GLY 12  12  12  GLY GLY B . n 
B 1 13  LYS 13  13  13  LYS LYS B . n 
B 1 14  ASP 14  14  14  ASP ASP B . n 
B 1 15  GLY 15  15  15  GLY GLY B . n 
B 1 16  LYS 16  16  16  LYS LYS B . n 
B 1 17  GLN 17  17  17  GLN GLN B . n 
B 1 18  THR 18  18  18  THR THR B . n 
B 1 19  LEU 19  19  19  LEU LEU B . n 
B 1 20  VAL 20  20  20  VAL VAL B . n 
B 1 21  LEU 21  21  21  LEU LEU B . n 
B 1 22  ASN 22  22  22  ASN ASN B . n 
B 1 23  PRO 23  23  23  PRO PRO B . n 
B 1 24  ARG 24  24  24  ARG ARG B . n 
B 1 25  GLY 25  25  25  GLY GLY B . n 
B 1 26  VAL 26  26  26  VAL VAL B . n 
B 1 27  ASN 27  27  27  ASN ASN B . n 
B 1 28  PRO 28  28  28  PRO PRO B . n 
B 1 29  THR 29  29  29  THR THR B . n 
B 1 30  ASN 30  30  30  ASN ASN B . n 
B 1 31  GLY 31  31  31  GLY GLY B . n 
B 1 32  VAL 32  32  32  VAL VAL B . n 
B 1 33  ALA 33  33  33  ALA ALA B . n 
B 1 34  SER 34  34  34  SER SER B . n 
B 1 35  LEU 35  35  35  LEU LEU B . n 
B 1 36  SER 36  36  36  SER SER B . n 
B 1 37  GLN 37  37  37  GLN GLN B . n 
B 1 38  ALA 38  38  38  ALA ALA B . n 
B 1 39  GLY 39  39  39  GLY GLY B . n 
B 1 40  ALA 40  40  40  ALA ALA B . n 
B 1 41  VAL 41  41  41  VAL VAL B . n 
B 1 42  PRO 42  42  42  PRO PRO B . n 
B 1 43  ALA 43  43  43  ALA ALA B . n 
B 1 44  LEU 44  44  44  LEU LEU B . n 
B 1 45  GLU 45  45  45  GLU GLU B . n 
B 1 46  LYS 46  46  46  LYS LYS B . n 
B 1 47  ARG 47  47  47  ARG ARG B . n 
B 1 48  VAL 48  48  48  VAL VAL B . n 
B 1 49  THR 49  49  49  THR THR B . n 
B 1 50  VAL 50  50  50  VAL VAL B . n 
B 1 51  SER 51  51  51  SER SER B . n 
B 1 52  VAL 52  52  52  VAL VAL B . n 
B 1 53  SER 53  53  53  SER SER B . n 
B 1 54  GLN 54  54  54  GLN GLN B . n 
B 1 55  PRO 55  55  55  PRO PRO B . n 
B 1 56  SER 56  56  56  SER SER B . n 
B 1 57  ARG 57  57  57  ARG ARG B . n 
B 1 58  ASN 58  58  58  ASN ASN B . n 
B 1 59  ARG 59  59  59  ARG ARG B . n 
B 1 60  LYS 60  60  60  LYS LYS B . n 
B 1 61  ASN 61  61  61  ASN ASN B . n 
B 1 62  TYR 62  62  62  TYR TYR B . n 
B 1 63  LYS 63  63  63  LYS LYS B . n 
B 1 64  VAL 64  64  64  VAL VAL B . n 
B 1 65  GLN 65  65  65  GLN GLN B . n 
B 1 66  VAL 66  66  66  VAL VAL B . n 
B 1 67  LYS 67  67  67  LYS LYS B . n 
B 1 68  ILE 68  68  68  ILE ILE B . n 
B 1 69  GLN 69  69  69  GLN GLN B . n 
B 1 70  ASN 70  70  70  ASN ASN B . n 
B 1 71  PRO 71  71  71  PRO PRO B . n 
B 1 72  THR 72  72  72  THR THR B . n 
B 1 73  ALA 73  73  73  ALA ALA B . n 
B 1 74  CYS 74  74  74  CYS CYS B . n 
B 1 75  THR 75  75  75  THR THR B . n 
B 1 76  ALA 76  76  76  ALA ALA B . n 
B 1 77  ASN 77  77  ?   ?   ?   B . n 
B 1 78  GLY 78  78  ?   ?   ?   B . n 
B 1 79  SER 79  79  ?   ?   ?   B . n 
B 1 80  CYS 80  80  ?   ?   ?   B . n 
B 1 81  ASP 81  81  81  ASP ASP B . n 
B 1 82  PRO 82  82  82  PRO PRO B . n 
B 1 83  SER 83  83  83  SER SER B . n 
B 1 84  VAL 84  84  84  VAL VAL B . n 
B 1 85  THR 85  85  85  THR THR B . n 
B 1 86  ARG 86  86  86  ARG ARG B . n 
B 1 87  GLN 87  87  87  GLN GLN B . n 
B 1 88  ALA 88  88  88  ALA ALA B . n 
B 1 89  TYR 89  89  89  TYR TYR B . n 
B 1 90  ALA 90  90  90  ALA ALA B . n 
B 1 91  ASP 91  91  91  ASP ASP B . n 
B 1 92  VAL 92  92  92  VAL VAL B . n 
B 1 93  THR 93  93  93  THR THR B . n 
B 1 94  PHE 94  94  94  PHE PHE B . n 
B 1 95  SER 95  95  95  SER SER B . n 
B 1 96  PHE 96  96  96  PHE PHE B . n 
B 1 97  THR 97  97  97  THR THR B . n 
B 1 98  GLN 98  98  98  GLN GLN B . n 
B 1 99  TYR 99  99  99  TYR TYR B . n 
B 1 100 SER 100 100 100 SER SER B . n 
B 1 101 THR 101 101 101 THR THR B . n 
B 1 102 ASP 102 102 102 ASP ASP B . n 
B 1 103 GLU 103 103 103 GLU GLU B . n 
B 1 104 GLU 104 104 104 GLU GLU B . n 
B 1 105 ARG 105 105 105 ARG ARG B . n 
B 1 106 ALA 106 106 106 ALA ALA B . n 
B 1 107 PHE 107 107 107 PHE PHE B . n 
B 1 108 VAL 108 108 108 VAL VAL B . n 
B 1 109 ARG 109 109 109 ARG ARG B . n 
B 1 110 THR 110 110 110 THR THR B . n 
B 1 111 GLU 111 111 111 GLU GLU B . n 
B 1 112 LEU 112 112 112 LEU LEU B . n 
B 1 113 ALA 113 113 113 ALA ALA B . n 
B 1 114 ALA 114 114 114 ALA ALA B . n 
B 1 115 LEU 115 115 115 LEU LEU B . n 
B 1 116 LEU 116 116 116 LEU LEU B . n 
B 1 117 ALA 117 117 117 ALA ALA B . n 
B 1 118 SER 118 118 118 SER SER B . n 
B 1 119 PRO 119 119 119 PRO PRO B . n 
B 1 120 LEU 120 120 120 LEU LEU B . n 
B 1 121 LEU 121 121 121 LEU LEU B . n 
B 1 122 ILE 122 122 122 ILE ILE B . n 
B 1 123 ASP 123 123 123 ASP ASP B . n 
B 1 124 ALA 124 124 124 ALA ALA B . n 
B 1 125 ILE 125 125 125 ILE ILE B . n 
B 1 126 ASP 126 126 126 ASP ASP B . n 
B 1 127 GLN 127 127 127 GLN GLN B . n 
B 1 128 LEU 128 128 128 LEU LEU B . n 
B 1 129 ASN 129 129 129 ASN ASN B . n 
B 1 130 PRO 130 130 130 PRO PRO B . n 
B 1 131 ALA 131 131 131 ALA ALA B . n 
B 1 132 TYR 132 132 ?   ?   ?   B . n 
C 2 1   ILE 1   5   5   ILE ILE L . n 
C 2 2   GLN 2   6   6   GLN GLN L . n 
C 2 3   MET 3   7   7   MET MET L . n 
C 2 4   THR 4   8   8   THR THR L . n 
C 2 5   GLN 5   9   9   GLN GLN L . n 
C 2 6   SER 6   10  10  SER SER L . n 
C 2 7   PRO 7   11  11  PRO PRO L . n 
C 2 8   SER 8   12  12  SER SER L . n 
C 2 9   SER 9   13  13  SER SER L . n 
C 2 10  LEU 10  14  14  LEU LEU L . n 
C 2 11  SER 11  15  15  SER SER L . n 
C 2 12  ALA 12  16  16  ALA ALA L . n 
C 2 13  SER 13  17  17  SER SER L . n 
C 2 14  LEU 14  18  18  LEU LEU L . n 
C 2 15  GLY 15  19  19  GLY GLY L . n 
C 2 16  GLU 16  20  20  GLU GLU L . n 
C 2 17  ARG 17  21  21  ARG ARG L . n 
C 2 18  VAL 18  22  22  VAL VAL L . n 
C 2 19  SER 19  23  23  SER SER L . n 
C 2 20  LEU 20  24  24  LEU LEU L . n 
C 2 21  THR 21  25  25  THR THR L . n 
C 2 22  CYS 22  26  26  CYS CYS L . n 
C 2 23  ARG 23  27  27  ARG ARG L . n 
C 2 24  ALA 24  28  28  ALA ALA L . n 
C 2 25  SER 25  29  29  SER SER L . n 
C 2 26  GLN 26  30  30  GLN GLN L . n 
C 2 27  ASP 27  31  31  ASP ASP L . n 
C 2 28  ILE 28  32  32  ILE ILE L . n 
C 2 29  GLY 29  33  33  GLY GLY L . n 
C 2 30  SER 30  34  34  SER SER L . n 
C 2 31  SER 31  35  35  SER SER L . n 
C 2 32  LEU 32  36  36  LEU LEU L . n 
C 2 33  ASN 33  37  37  ASN ASN L . n 
C 2 34  TRP 34  38  38  TRP TRP L . n 
C 2 35  LEU 35  39  39  LEU LEU L . n 
C 2 36  GLN 36  40  40  GLN GLN L . n 
C 2 37  GLN 37  41  41  GLN GLN L . n 
C 2 38  LYS 38  42  42  LYS LYS L . n 
C 2 39  PRO 39  43  43  PRO PRO L . n 
C 2 40  ASP 40  44  44  ASP ASP L . n 
C 2 41  GLY 41  45  45  GLY GLY L . n 
C 2 42  THR 42  46  46  THR THR L . n 
C 2 43  ILE 43  47  47  ILE ILE L . n 
C 2 44  LYS 44  48  48  LYS LYS L . n 
C 2 45  ARG 45  49  49  ARG ARG L . n 
C 2 46  LEU 46  50  50  LEU LEU L . n 
C 2 47  ILE 47  51  51  ILE ILE L . n 
C 2 48  TYR 48  52  52  TYR TYR L . n 
C 2 49  ALA 49  53  53  ALA ALA L . n 
C 2 50  THR 50  54  54  THR THR L . n 
C 2 51  SER 51  55  55  SER SER L . n 
C 2 52  ASN 52  56  56  ASN ASN L . n 
C 2 53  LEU 53  57  57  LEU LEU L . n 
C 2 54  ASP 54  58  58  ASP ASP L . n 
C 2 55  SER 55  59  59  SER SER L . n 
C 2 56  GLY 56  60  60  GLY GLY L . n 
C 2 57  VAL 57  61  61  VAL VAL L . n 
C 2 58  PRO 58  62  62  PRO PRO L . n 
C 2 59  LYS 59  63  63  LYS LYS L . n 
C 2 60  ARG 60  64  64  ARG ARG L . n 
C 2 61  PHE 61  65  65  PHE PHE L . n 
C 2 62  SER 62  66  66  SER SER L . n 
C 2 63  GLY 63  67  67  GLY GLY L . n 
C 2 64  SER 64  68  68  SER SER L . n 
C 2 65  ARG 65  69  69  ARG ARG L . n 
C 2 66  SER 66  70  70  SER SER L . n 
C 2 67  GLY 67  71  71  GLY GLY L . n 
C 2 68  SER 68  72  72  SER SER L . n 
C 2 69  ASP 69  73  73  ASP ASP L . n 
C 2 70  TYR 70  74  74  TYR TYR L . n 
C 2 71  SER 71  75  75  SER SER L . n 
C 2 72  LEU 72  76  76  LEU LEU L . n 
C 2 73  THR 73  77  77  THR THR L . n 
C 2 74  ILE 74  78  78  ILE ILE L . n 
C 2 75  SER 75  79  79  SER SER L . n 
C 2 76  SER 76  80  80  SER SER L . n 
C 2 77  LEU 77  81  81  LEU LEU L . n 
C 2 78  GLU 78  82  82  GLU GLU L . n 
C 2 79  THR 79  83  83  THR THR L . n 
C 2 80  GLU 80  84  84  GLU GLU L . n 
C 2 81  ASP 81  85  85  ASP ASP L . n 
C 2 82  PHE 82  86  86  PHE PHE L . n 
C 2 83  VAL 83  87  87  VAL VAL L . n 
C 2 84  ASP 84  88  88  ASP ASP L . n 
C 2 85  TYR 85  89  89  TYR TYR L . n 
C 2 86  TYR 86  90  90  TYR TYR L . n 
C 2 87  CYS 87  91  91  CYS CYS L . n 
C 2 88  LEU 88  92  92  LEU LEU L . n 
C 2 89  GLN 89  93  93  GLN GLN L . n 
C 2 90  TYR 90  94  94  TYR TYR L . n 
C 2 91  ALA 91  95  95  ALA ALA L . n 
C 2 92  THR 92  96  96  THR THR L . n 
C 2 93  SER 93  97  97  SER SER L . n 
C 2 94  PRO 94  98  98  PRO PRO L . n 
C 2 95  TYR 95  99  99  TYR TYR L . n 
C 2 96  THR 96  100 100 THR THR L . n 
C 2 97  PHE 97  101 101 PHE PHE L . n 
C 2 98  GLY 98  102 102 GLY GLY L . n 
C 2 99  GLY 99  103 103 GLY GLY L . n 
C 2 100 GLY 100 104 104 GLY GLY L . n 
C 2 101 THR 101 105 105 THR THR L . n 
D 3 1   ILE 1   23  23  ILE ILE H . n 
D 3 2   SER 2   24  24  SER SER H . n 
D 3 3   CYS 3   25  25  CYS CYS H . n 
D 3 4   LYS 4   26  26  LYS LYS H . n 
D 3 5   SER 5   27  27  SER SER H . n 
D 3 6   SER 6   28  28  SER SER H . n 
D 3 7   GLY 7   29  29  GLY GLY H . n 
D 3 8   TYR 8   30  30  TYR TYR H . n 
D 3 9   ALA 9   31  31  ALA ALA H . n 
D 3 10  PHE 10  32  32  PHE PHE H . n 
D 3 11  SER 11  33  33  SER SER H . n 
D 3 12  SER 12  34  34  SER SER H . n 
D 3 13  SER 13  35  35  SER SER H . n 
D 3 14  TRP 14  36  36  TRP TRP H . n 
D 3 15  MET 15  37  37  MET MET H . n 
D 3 16  ASN 16  38  38  ASN ASN H . n 
D 3 17  TRP 17  39  39  TRP TRP H . n 
D 3 18  VAL 18  40  40  VAL VAL H . n 
D 3 19  LYS 19  41  41  LYS LYS H . n 
D 3 20  GLN 20  42  ?   ?   ?   H . n 
D 3 21  ARG 21  43  ?   ?   ?   H . n 
D 3 22  PRO 22  44  ?   ?   ?   H . n 
D 3 23  GLY 23  45  ?   ?   ?   H . n 
D 3 24  LYS 24  46  ?   ?   ?   H . n 
D 3 25  GLY 25  47  ?   ?   ?   H . n 
D 3 26  LEU 26  48  ?   ?   ?   H . n 
D 3 27  GLU 27  49  ?   ?   ?   H . n 
D 3 28  TRP 28  50  ?   ?   ?   H . n 
D 3 29  ILE 29  51  51  ILE ILE H . n 
D 3 30  GLY 30  52  52  GLY GLY H . n 
D 3 31  ARG 31  53  53  ARG ARG H . n 
D 3 32  ILE 32  54  54  ILE ILE H . n 
D 3 33  TYR 33  55  55  TYR TYR H . n 
D 3 34  PRO 34  56  56  PRO PRO H . n 
D 3 35  GLU 35  57  57  GLU GLU H . n 
D 3 36  ASN 36  58  58  ASN ASN H . n 
D 3 37  GLY 37  59  59  GLY GLY H . n 
D 3 38  GLU 38  60  60  GLU GLU H . n 
D 3 39  THR 39  61  61  THR THR H . n 
D 3 40  ASN 40  62  62  ASN ASN H . n 
D 3 41  TYR 41  63  63  TYR TYR H . n 
D 3 42  ASN 42  64  64  ASN ASN H . n 
D 3 43  GLY 43  65  65  GLY GLY H . n 
D 3 44  LYS 44  66  66  LYS LYS H . n 
D 3 45  PHE 45  67  67  PHE PHE H . n 
D 3 46  LYS 46  68  68  LYS LYS H . n 
D 3 47  GLY 47  69  69  GLY GLY H . n 
D 3 48  LYS 48  70  70  LYS LYS H . n 
D 3 49  ALA 49  71  71  ALA ALA H . n 
D 3 50  THR 50  72  72  THR THR H . n 
D 3 51  LEU 51  73  73  LEU LEU H . n 
D 3 52  THR 52  74  74  THR THR H . n 
D 3 53  ALA 53  75  75  ALA ALA H . n 
D 3 54  ASP 54  76  76  ASP ASP H . n 
D 3 55  LYS 55  77  77  LYS LYS H . n 
D 3 56  SER 56  78  78  SER SER H . n 
D 3 57  SER 57  79  79  SER SER H . n 
D 3 58  ARG 58  80  80  ARG ARG H . n 
D 3 59  SER 59  81  81  SER SER H . n 
D 3 60  ALA 60  82  82  ALA ALA H . n 
D 3 61  TYR 61  83  83  TYR TYR H . n 
D 3 62  MET 62  84  84  MET MET H . n 
D 3 63  GLN 63  85  85  GLN GLN H . n 
D 3 64  LEU 64  86  86  LEU LEU H . n 
D 3 65  ASN 65  87  87  ASN ASN H . n 
D 3 66  SER 66  88  88  SER SER H . n 
D 3 67  LEU 67  89  89  LEU LEU H . n 
D 3 68  THR 68  90  90  THR THR H . n 
D 3 69  SER 69  91  91  SER SER H . n 
D 3 70  GLU 70  92  92  GLU GLU H . n 
D 3 71  ASP 71  93  93  ASP ASP H . n 
D 3 72  SER 72  94  94  SER SER H . n 
D 3 73  ALA 73  95  95  ALA ALA H . n 
D 3 74  VAL 74  96  96  VAL VAL H . n 
D 3 75  TYR 75  97  97  TYR TYR H . n 
D 3 76  PHE 76  98  98  PHE PHE H . n 
D 3 77  CYS 77  99  99  CYS CYS H . n 
D 3 78  ALA 78  100 100 ALA ALA H . n 
D 3 79  ARG 79  101 101 ARG ARG H . n 
D 3 80  SER 80  102 102 SER SER H . n 
D 3 81  GLY 81  103 103 GLY GLY H . n 
D 3 82  TYR 82  104 104 TYR TYR H . n 
D 3 83  TYR 83  105 105 TYR TYR H . n 
D 3 84  PHE 84  106 106 PHE PHE H . n 
D 3 85  SER 85  107 107 SER SER H . n 
D 3 86  SER 86  108 108 SER SER H . n 
D 3 87  ASN 87  109 109 ASN ASN H . n 
D 3 88  TYR 88  110 110 TYR TYR H . n 
D 3 89  ASP 89  111 111 ASP ASP H . n 
D 3 90  PHE 90  112 112 PHE PHE H . n 
E 1 1   ALA 1   1   1   ALA ALA C . n 
E 1 2   LYS 2   2   2   LYS LYS C . n 
E 1 3   LEU 3   3   3   LEU LEU C . n 
E 1 4   GLU 4   4   4   GLU GLU C . n 
E 1 5   THR 5   5   5   THR THR C . n 
E 1 6   VAL 6   6   6   VAL VAL C . n 
E 1 7   THR 7   7   7   THR THR C . n 
E 1 8   LEU 8   8   8   LEU LEU C . n 
E 1 9   GLY 9   9   9   GLY GLY C . n 
E 1 10  ASN 10  10  10  ASN ASN C . n 
E 1 11  ILE 11  11  11  ILE ILE C . n 
E 1 12  GLY 12  12  12  GLY GLY C . n 
E 1 13  LYS 13  13  13  LYS LYS C . n 
E 1 14  ASP 14  14  14  ASP ASP C . n 
E 1 15  GLY 15  15  15  GLY GLY C . n 
E 1 16  LYS 16  16  16  LYS LYS C . n 
E 1 17  GLN 17  17  17  GLN GLN C . n 
E 1 18  THR 18  18  18  THR THR C . n 
E 1 19  LEU 19  19  19  LEU LEU C . n 
E 1 20  VAL 20  20  20  VAL VAL C . n 
E 1 21  LEU 21  21  21  LEU LEU C . n 
E 1 22  ASN 22  22  22  ASN ASN C . n 
E 1 23  PRO 23  23  23  PRO PRO C . n 
E 1 24  ARG 24  24  24  ARG ARG C . n 
E 1 25  GLY 25  25  25  GLY GLY C . n 
E 1 26  VAL 26  26  26  VAL VAL C . n 
E 1 27  ASN 27  27  27  ASN ASN C . n 
E 1 28  PRO 28  28  28  PRO PRO C . n 
E 1 29  THR 29  29  29  THR THR C . n 
E 1 30  ASN 30  30  30  ASN ASN C . n 
E 1 31  GLY 31  31  31  GLY GLY C . n 
E 1 32  VAL 32  32  32  VAL VAL C . n 
E 1 33  ALA 33  33  33  ALA ALA C . n 
E 1 34  SER 34  34  34  SER SER C . n 
E 1 35  LEU 35  35  35  LEU LEU C . n 
E 1 36  SER 36  36  36  SER SER C . n 
E 1 37  GLN 37  37  37  GLN GLN C . n 
E 1 38  ALA 38  38  38  ALA ALA C . n 
E 1 39  GLY 39  39  39  GLY GLY C . n 
E 1 40  ALA 40  40  40  ALA ALA C . n 
E 1 41  VAL 41  41  41  VAL VAL C . n 
E 1 42  PRO 42  42  42  PRO PRO C . n 
E 1 43  ALA 43  43  43  ALA ALA C . n 
E 1 44  LEU 44  44  44  LEU LEU C . n 
E 1 45  GLU 45  45  45  GLU GLU C . n 
E 1 46  LYS 46  46  46  LYS LYS C . n 
E 1 47  ARG 47  47  47  ARG ARG C . n 
E 1 48  VAL 48  48  48  VAL VAL C . n 
E 1 49  THR 49  49  49  THR THR C . n 
E 1 50  VAL 50  50  50  VAL VAL C . n 
E 1 51  SER 51  51  51  SER SER C . n 
E 1 52  VAL 52  52  52  VAL VAL C . n 
E 1 53  SER 53  53  53  SER SER C . n 
E 1 54  GLN 54  54  54  GLN GLN C . n 
E 1 55  PRO 55  55  55  PRO PRO C . n 
E 1 56  SER 56  56  ?   ?   ?   C . n 
E 1 57  ARG 57  57  ?   ?   ?   C . n 
E 1 58  ASN 58  58  ?   ?   ?   C . n 
E 1 59  ARG 59  59  ?   ?   ?   C . n 
E 1 60  LYS 60  60  ?   ?   ?   C . n 
E 1 61  ASN 61  61  61  ASN ASN C . n 
E 1 62  TYR 62  62  62  TYR TYR C . n 
E 1 63  LYS 63  63  63  LYS LYS C . n 
E 1 64  VAL 64  64  64  VAL VAL C . n 
E 1 65  GLN 65  65  65  GLN GLN C . n 
E 1 66  VAL 66  66  66  VAL VAL C . n 
E 1 67  LYS 67  67  67  LYS LYS C . n 
E 1 68  ILE 68  68  68  ILE ILE C . n 
E 1 69  GLN 69  69  69  GLN GLN C . n 
E 1 70  ASN 70  70  70  ASN ASN C . n 
E 1 71  PRO 71  71  71  PRO PRO C . n 
E 1 72  THR 72  72  72  THR THR C . n 
E 1 73  ALA 73  73  73  ALA ALA C . n 
E 1 74  CYS 74  74  74  CYS CYS C . n 
E 1 75  THR 75  75  75  THR THR C . n 
E 1 76  ALA 76  76  76  ALA ALA C . n 
E 1 77  ASN 77  77  77  ASN ASN C . n 
E 1 78  GLY 78  78  78  GLY GLY C . n 
E 1 79  SER 79  79  79  SER SER C . n 
E 1 80  CYS 80  80  80  CYS CYS C . n 
E 1 81  ASP 81  81  81  ASP ASP C . n 
E 1 82  PRO 82  82  82  PRO PRO C . n 
E 1 83  SER 83  83  83  SER SER C . n 
E 1 84  VAL 84  84  84  VAL VAL C . n 
E 1 85  THR 85  85  85  THR THR C . n 
E 1 86  ARG 86  86  86  ARG ARG C . n 
E 1 87  GLN 87  87  87  GLN GLN C . n 
E 1 88  ALA 88  88  88  ALA ALA C . n 
E 1 89  TYR 89  89  89  TYR TYR C . n 
E 1 90  ALA 90  90  90  ALA ALA C . n 
E 1 91  ASP 91  91  91  ASP ASP C . n 
E 1 92  VAL 92  92  92  VAL VAL C . n 
E 1 93  THR 93  93  93  THR THR C . n 
E 1 94  PHE 94  94  94  PHE PHE C . n 
E 1 95  SER 95  95  95  SER SER C . n 
E 1 96  PHE 96  96  96  PHE PHE C . n 
E 1 97  THR 97  97  97  THR THR C . n 
E 1 98  GLN 98  98  98  GLN GLN C . n 
E 1 99  TYR 99  99  99  TYR TYR C . n 
E 1 100 SER 100 100 100 SER SER C . n 
E 1 101 THR 101 101 101 THR THR C . n 
E 1 102 ASP 102 102 102 ASP ASP C . n 
E 1 103 GLU 103 103 103 GLU GLU C . n 
E 1 104 GLU 104 104 104 GLU GLU C . n 
E 1 105 ARG 105 105 105 ARG ARG C . n 
E 1 106 ALA 106 106 106 ALA ALA C . n 
E 1 107 PHE 107 107 107 PHE PHE C . n 
E 1 108 VAL 108 108 108 VAL VAL C . n 
E 1 109 ARG 109 109 109 ARG ARG C . n 
E 1 110 THR 110 110 110 THR THR C . n 
E 1 111 GLU 111 111 111 GLU GLU C . n 
E 1 112 LEU 112 112 112 LEU LEU C . n 
E 1 113 ALA 113 113 113 ALA ALA C . n 
E 1 114 ALA 114 114 114 ALA ALA C . n 
E 1 115 LEU 115 115 115 LEU LEU C . n 
E 1 116 LEU 116 116 116 LEU LEU C . n 
E 1 117 ALA 117 117 117 ALA ALA C . n 
E 1 118 SER 118 118 118 SER SER C . n 
E 1 119 PRO 119 119 119 PRO PRO C . n 
E 1 120 LEU 120 120 120 LEU LEU C . n 
E 1 121 LEU 121 121 121 LEU LEU C . n 
E 1 122 ILE 122 122 122 ILE ILE C . n 
E 1 123 ASP 123 123 123 ASP ASP C . n 
E 1 124 ALA 124 124 124 ALA ALA C . n 
E 1 125 ILE 125 125 125 ILE ILE C . n 
E 1 126 ASP 126 126 126 ASP ASP C . n 
E 1 127 GLN 127 127 127 GLN GLN C . n 
E 1 128 LEU 128 128 128 LEU LEU C . n 
E 1 129 ASN 129 129 129 ASN ASN C . n 
E 1 130 PRO 130 130 130 PRO PRO C . n 
E 1 131 ALA 131 131 131 ALA ALA C . n 
E 1 132 TYR 132 132 132 TYR TYR C . n 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8W5G 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8W5G 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8W5G 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 8W5G 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.003 ? 4362 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.580 ? 5925 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 4.968 ? 610  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.044 ? 694  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.005 ? 771  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8W5G 
_struct.title                        'Cryo-EM structure of Qb-Ab7' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8W5G 
_struct_keywords.text            'Qb, Antibody, cryo-EM, IMMUNE SYSTEM' 
_struct_keywords.pdbx_keywords   'IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 3 ? 
E N N 1 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP A1_BPQBE Q8LTE1 ? 1 
;AKLETVTLGNIGKDGKQTLVLNPRGVNPTNGVASLSQAGAVPALEKRVTVSVSQPSRNRKNYKVQVKIQNPTACTANGSC
DPSVTRQAYADVTFSFTQYSTDEERAFVRTELAALLASPLLIDAIDQLNPAY
;
2 
2 PDB 8W5G     8W5G   ? 2 ? 1 
3 PDB 8W5G     8W5G   ? 3 ? 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8W5G A 1 ? 132 ? Q8LTE1 2  ? 133 ? 1  132 
2 1 8W5G B 1 ? 132 ? Q8LTE1 2  ? 133 ? 1  132 
3 2 8W5G L 1 ? 101 ? 8W5G   5  ? 105 ? 5  105 
4 3 8W5G H 1 ? 90  ? 8W5G   23 ? 112 ? 23 112 
5 1 8W5G C 1 ? 132 ? Q8LTE1 2  ? 133 ? 1  132 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 'complete icosahedral assembly'                ? 300-meric  300 
2 'icosahedral asymmetric unit'                  ? pentameric 5   
3 'icosahedral pentamer'                         ? 25-meric   25  
4 'icosahedral 23 hexamer'                       ? 30-meric   30  
5 'icosahedral asymmetric unit, std point frame' ? pentameric 5   
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 '(1-60)'           A,B,C,D,E 
2 1                  A,B,C,D,E 
3 '(1-5)'            A,B,C,D,E 
4 '(1,2,6,10,23,24)' A,B,C,D,E 
5 P                  A,B,C,D,E 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
P  'transform to point frame' ?     ?     0.30901699  -0.80901699 0.50000000  0.00000    0.80901699  0.50000000  0.30901699  
-440.10524 -0.50000000 0.30901699  0.80901699  -168.10524 
1  'identity operation'       1_555 x,y,z 1.00000000  0.00000000  0.00000000  0.00000    0.00000000  1.00000000  0.00000000  
0.00000    0.00000000  0.00000000  1.00000000  0.00000    
2  'point symmetry operation' ?     ?     0.30901699  -0.80901700 0.50000000  272.00000  0.80901699  0.50000000  0.30901699  
-168.10524 -0.50000000 0.30901699  0.80901700  103.89476  
3  'point symmetry operation' ?     ?     -0.80901700 -0.50000000 0.30901700  544.00000  0.50000000  -0.30901699 0.80901700  
0.00000    -0.30901700 0.80901699  0.50000000  0.00000    
4  'point symmetry operation' ?     ?     -0.80901699 0.50000000  -0.30901700 440.10524  -0.50000000 -0.30901700 0.80901700  
272.00000  0.30901699  0.80901700  0.50000000  -168.10524 
5  'point symmetry operation' ?     ?     0.30901700  0.80901699  -0.50000000 103.89475  -0.80901699 0.50000000  0.30901700  
272.00000  0.50000000  0.30901700  0.80901699  -168.10524 
6  'point symmetry operation' ?     ?     -0.50000000 -0.30901699 -0.80901699 712.10524  -0.30901700 -0.80901699 0.50000001  
440.10524  -0.80901700 0.49999999  0.30901699  272.00000  
7  'point symmetry operation' ?     ?     0.00000000  0.00000000  -1.00000000 543.99999  -1.00000000 0.00000000  0.00000000  
544.00000  0.00000000  1.00000000  0.00000000  0.00000    
8  'point symmetry operation' ?     ?     0.50000000  -0.30901699 -0.80901699 440.10524  -0.30901699 0.80901700  -0.50000000 
272.00000  0.80901700  0.50000000  0.30901699  -168.10524 
9  'point symmetry operation' ?     ?     0.30901699  -0.80901699 -0.50000000 544.00000  0.80901700  0.50000000  -0.30901699 
0.00000    0.50000000  -0.30901700 0.80901699  0.00000    
10 'point symmetry operation' ?     ?     -0.30901700 -0.80901699 -0.50000000 712.10524  0.80901699  -0.50000000 0.30901700  
103.89475  -0.50000000 -0.30901700 0.80901699  272.00000  
11 'point symmetry operation' ?     ?     0.30901699  0.80901700  0.49999999  -168.10524 0.80901699  -0.50000000 0.30901699  
103.89475  0.50000001  0.30901700  -0.80901699 271.99999  
12 'point symmetry operation' ?     ?     0.50000000  0.30901700  0.80901699  -168.10524 -0.30901700 -0.80901700 0.50000000  
440.10524  0.80901700  -0.50000000 -0.30901699 271.99999  
13 'point symmetry operation' ?     ?     0.00000000  0.00000000  1.00000000  0.00000    -1.00000000 0.00000000  0.00000000  
544.00000  0.00000000  -1.00000000 0.00000000  543.99999  
14 'point symmetry operation' ?     ?     -0.50000000 0.30901699  0.80901700  103.89476  -0.30901699 0.80901699  -0.50000000 
272.00000  -0.80901700 -0.50000000 -0.30901699 712.10524  
15 'point symmetry operation' ?     ?     -0.30901700 0.80901699  0.50000000  0.00000    0.80901699  0.50000000  -0.30901700 
0.00000    -0.50000000 0.30901700  -0.80901699 543.99999  
16 'point symmetry operation' ?     ?     -0.80901699 -0.50000001 0.30901700  544.00000  -0.49999999 0.30901699  -0.80901700 
544.00000  0.30901699  -0.80901699 -0.50000000 543.99999  
17 'point symmetry operation' ?     ?     -0.80901699 0.50000000  -0.30901699 440.10524  0.50000000  0.30901699  -0.80901700 
272.00000  -0.30901700 -0.80901699 -0.50000000 712.10524  
18 'point symmetry operation' ?     ?     0.30901699  0.80901700  -0.50000000 103.89475  0.80901699  -0.50000000 -0.30901700 
272.00000  -0.50000000 -0.30901699 -0.80901699 712.10524  
19 'point symmetry operation' ?     ?     1.00000000  0.00000000  0.00000000  0.00000    0.00000000  -1.00000000 0.00000000  
544.00000  0.00000000  0.00000000  -1.00000000 543.99999  
20 'point symmetry operation' ?     ?     0.30901700  -0.80901699 0.50000000  272.00000  -0.80901699 -0.50000000 -0.30901700 
712.10524  0.50000000  -0.30901700 -0.80901699 440.10524  
21 'point symmetry operation' ?     ?     -0.30901700 -0.80901699 0.50000001  440.10524  0.80901700  -0.49999999 -0.30901699 
271.99999  0.50000000  0.30901699  0.80901699  -168.10524 
22 'point symmetry operation' ?     ?     -1.00000000 0.00000000  0.00000000  544.00000  0.00000000  -1.00000000 0.00000000  
543.99999  0.00000000  0.00000000  1.00000000  0.00000    
23 'point symmetry operation' ?     ?     -0.30901699 0.80901700  -0.50000000 272.00000  -0.80901700 -0.50000000 -0.30901699 
712.10524  -0.50000000 0.30901699  0.80901699  103.89476  
24 'point symmetry operation' ?     ?     0.80901700  0.50000000  -0.30901699 0.00000    -0.50000000 0.30901700  -0.80901699 
543.99999  -0.30901699 0.80901699  0.50000000  0.00000    
25 'point symmetry operation' ?     ?     0.80901699  -0.50000000 0.30901700  103.89475  0.50000000  0.30901700  -0.80901699 
271.99999  0.30901700  0.80901699  0.50000000  -168.10524 
26 'point symmetry operation' ?     ?     0.00000000  1.00000000  0.00000000  0.00000    0.00000000  0.00000000  -1.00000000 
544.00000  -1.00000000 0.00000000  0.00000000  544.00000  
27 'point symmetry operation' ?     ?     0.80901699  0.50000000  0.30901699  -168.10524 0.50000000  -0.30901699 -0.80901700 
440.10524  -0.30901699 0.80901700  -0.50000000 272.00000  
28 'point symmetry operation' ?     ?     0.50000000  -0.30901699 0.80901700  0.00000    0.30901700  -0.80901699 -0.50000000 
543.99999  0.80901700  0.50000000  -0.30901700 0.00000    
29 'point symmetry operation' ?     ?     -0.50000000 -0.30901700 0.80901700  272.00000  -0.30901699 -0.80901700 -0.50000000 
712.10524  0.80901699  -0.50000000 0.30901700  103.89475  
30 'point symmetry operation' ?     ?     -0.80901699 0.50000000  0.30901700  272.00000  -0.50000000 -0.30901700 -0.80901699 
712.10524  -0.30901700 -0.80901699 0.50000000  440.10524  
31 'point symmetry operation' ?     ?     -0.49999999 0.30901699  -0.80901700 544.00000  -0.30901699 0.80901699  0.50000000  
0.00000    0.80901699  0.50000001  -0.30901700 0.00000    
32 'point symmetry operation' ?     ?     0.50000000  0.30901699  -0.80901700 272.00000  0.30901700  0.80901699  0.50000000  
-168.10524 0.80901699  -0.50000000 0.30901699  103.89475  
33 'point symmetry operation' ?     ?     0.80901699  -0.50000000 -0.30901700 272.00000  0.50000000  0.30901699  0.80901699  
-168.10524 -0.30901699 -0.80901700 0.50000000  440.10524  
34 'point symmetry operation' ?     ?     0.00000000  -1.00000000 0.00000000  544.00000  0.00000000  0.00000000  1.00000000  
0.00000    -1.00000000 0.00000000  0.00000000  544.00000  
35 'point symmetry operation' ?     ?     -0.80901699 -0.50000000 -0.30901700 712.10524  -0.50000000 0.30901700  0.80901699  
103.89476  -0.30901700 0.80901699  -0.50000000 272.00000  
36 'point symmetry operation' ?     ?     0.80901699  -0.50000000 0.30901699  103.89475  -0.50000001 -0.30901700 0.80901699  
272.00000  -0.30901699 -0.80901700 -0.49999999 712.10524  
37 'point symmetry operation' ?     ?     -0.30901700 -0.80901700 0.50000000  440.10524  -0.80901700 0.50000000  0.30901699  
272.00000  -0.50000000 -0.30901700 -0.80901699 712.10524  
38 'point symmetry operation' ?     ?     -1.00000000 0.00000000  0.00000000  544.00000  0.00000000  1.00000000  0.00000000  
0.00000    0.00000000  0.00000000  -1.00000000 543.99999  
39 'point symmetry operation' ?     ?     -0.30901699 0.80901699  -0.50000000 272.00000  0.80901700  0.50000000  0.30901699  
-168.10524 0.50000000  -0.30901699 -0.80901700 440.10524  
40 'point symmetry operation' ?     ?     0.80901699  0.50000000  -0.30901700 0.00000    0.50000000  -0.30901700 0.80901699  
0.00000    0.30901700  -0.80901699 -0.50000000 543.99999  
41 'point symmetry operation' ?     ?     -0.30901699 0.80901699  0.50000000  0.00000    -0.80901699 -0.50000001 0.30901700  
544.00000  0.49999999  -0.30901699 0.80901700  0.00000    
42 'point symmetry operation' ?     ?     0.30901700  0.80901699  0.50000000  -168.10524 -0.80901699 0.50000000  -0.30901699 
440.10524  -0.50000000 -0.30901699 0.80901700  272.00000  
43 'point symmetry operation' ?     ?     0.50000000  0.30901699  0.80901699  -168.10524 0.30901699  0.80901700  -0.50000000 
103.89475  -0.80901699 0.50000000  0.30901700  272.00000  
44 'point symmetry operation' ?     ?     0.00000000  0.00000000  1.00000000  0.00000    1.00000000  0.00000000  0.00000000  
0.00000    0.00000000  1.00000000  0.00000000  0.00000    
45 'point symmetry operation' ?     ?     -0.50000000 0.30901700  0.80901699  103.89476  0.30901700  -0.80901699 0.50000000  
272.00000  0.80901699  0.50000000  0.30901700  -168.10525 
46 'point symmetry operation' ?     ?     -0.50000001 -0.30901700 0.80901699  272.00000  0.30901699  0.80901700  0.49999999  
-168.10524 -0.80901699 0.50000000  -0.30901699 440.10524  
47 'point symmetry operation' ?     ?     -0.80901700 0.50000000  0.30901699  272.00000  0.50000000  0.30901700  0.80901699  
-168.10524 0.30901700  0.80901700  -0.50000000 103.89475  
48 'point symmetry operation' ?     ?     0.00000000  1.00000000  0.00000000  0.00000    0.00000000  0.00000000  1.00000000  
0.00000    1.00000000  0.00000000  0.00000000  0.00000    
49 'point symmetry operation' ?     ?     0.80901700  0.50000000  0.30901699  -168.10524 -0.50000000 0.30901699  0.80901700  
103.89476  0.30901699  -0.80901699 0.50000000  272.00000  
50 'point symmetry operation' ?     ?     0.50000000  -0.30901700 0.80901699  0.00000    -0.30901700 0.80901699  0.50000000  
0.00000    -0.80901699 -0.50000000 0.30901700  544.00000  
51 'point symmetry operation' ?     ?     0.80901700  -0.49999999 -0.30901699 271.99999  -0.50000000 -0.30901699 -0.80901699 
712.10524  0.30901700  0.80901699  -0.50000001 103.89475  
52 'point symmetry operation' ?     ?     0.00000000  -1.00000000 0.00000000  544.00000  0.00000000  0.00000000  -1.00000000 
543.99999  1.00000000  0.00000000  0.00000000  0.00000    
53 'point symmetry operation' ?     ?     -0.80901700 -0.50000000 -0.30901699 712.10524  0.50000000  -0.30901699 -0.80901699 
440.10524  0.30901699  -0.80901700 0.50000000  272.00000  
54 'point symmetry operation' ?     ?     -0.50000000 0.30901700  -0.80901699 544.00000  0.30901699  -0.80901699 -0.50000000 
543.99999  -0.80901700 -0.50000000 0.30901699  544.00000  
55 'point symmetry operation' ?     ?     0.50000000  0.30901700  -0.80901699 272.00000  -0.30901700 -0.80901699 -0.50000000 
712.10524  -0.80901699 0.50000000  -0.30901700 440.10524  
56 'point symmetry operation' ?     ?     0.00000000  0.00000000  -1.00000000 544.00000  1.00000000  0.00000000  0.00000000  
0.00000    0.00000000  -1.00000000 0.00000000  544.00000  
57 'point symmetry operation' ?     ?     0.50000000  -0.30901699 -0.80901700 440.10524  0.30901699  -0.80901700 0.50000000  
272.00000  -0.80901699 -0.50000000 -0.30901699 712.10524  
58 'point symmetry operation' ?     ?     0.30901700  -0.80901699 -0.50000000 543.99999  -0.80901700 -0.50000000 0.30901700  
544.00000  -0.50000000 0.30901699  -0.80901700 544.00000  
59 'point symmetry operation' ?     ?     -0.30901699 -0.80901700 -0.50000000 712.10524  -0.80901699 0.50000000  -0.30901700 
440.10524  0.50000000  0.30901700  -0.80901700 272.00000  
60 'point symmetry operation' ?     ?     -0.50000000 -0.30901700 -0.80901699 712.10524  0.30901700  0.80901699  -0.50000000 
103.89475  0.80901699  -0.50000000 -0.30901700 272.00000  
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 AA1 THR A 101 ? LEU A 116 ? THR A 101 LEU A 116 1 ? 16 
HELX_P HELX_P2 AA2 SER A 118 ? GLN A 127 ? SER A 118 GLN A 127 1 ? 10 
HELX_P HELX_P3 AA3 GLY B 12  ? LYS B 16  ? GLY B 12  LYS B 16  5 ? 5  
HELX_P HELX_P4 AA4 THR B 101 ? LEU B 116 ? THR B 101 LEU B 116 1 ? 16 
HELX_P HELX_P5 AA5 SER B 118 ? ASP B 126 ? SER B 118 ASP B 126 1 ? 9  
HELX_P HELX_P6 AA6 THR E 101 ? LEU E 116 ? THR C 101 LEU C 116 1 ? 16 
HELX_P HELX_P7 AA7 SER E 118 ? GLN E 127 ? SER C 118 GLN C 127 1 ? 10 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_conn.id                            disulf1 
_struct_conn.conn_type_id                  disulf 
_struct_conn.pdbx_leaving_atom_flag        ? 
_struct_conn.pdbx_PDB_id                   ? 
_struct_conn.ptnr1_label_asym_id           C 
_struct_conn.ptnr1_label_comp_id           CYS 
_struct_conn.ptnr1_label_seq_id            22 
_struct_conn.ptnr1_label_atom_id           SG 
_struct_conn.pdbx_ptnr1_label_alt_id       ? 
_struct_conn.pdbx_ptnr1_PDB_ins_code       ? 
_struct_conn.pdbx_ptnr1_standard_comp_id   ? 
_struct_conn.ptnr1_symmetry                1_555 
_struct_conn.ptnr2_label_asym_id           C 
_struct_conn.ptnr2_label_comp_id           CYS 
_struct_conn.ptnr2_label_seq_id            87 
_struct_conn.ptnr2_label_atom_id           SG 
_struct_conn.pdbx_ptnr2_label_alt_id       ? 
_struct_conn.pdbx_ptnr2_PDB_ins_code       ? 
_struct_conn.ptnr1_auth_asym_id            L 
_struct_conn.ptnr1_auth_comp_id            CYS 
_struct_conn.ptnr1_auth_seq_id             26 
_struct_conn.ptnr2_auth_asym_id            L 
_struct_conn.ptnr2_auth_comp_id            CYS 
_struct_conn.ptnr2_auth_seq_id             91 
_struct_conn.ptnr2_symmetry                1_555 
_struct_conn.pdbx_ptnr3_label_atom_id      ? 
_struct_conn.pdbx_ptnr3_label_seq_id       ? 
_struct_conn.pdbx_ptnr3_label_comp_id      ? 
_struct_conn.pdbx_ptnr3_label_asym_id      ? 
_struct_conn.pdbx_ptnr3_label_alt_id       ? 
_struct_conn.pdbx_ptnr3_PDB_ins_code       ? 
_struct_conn.details                       ? 
_struct_conn.pdbx_dist_value               2.035 
_struct_conn.pdbx_value_order              ? 
_struct_conn.pdbx_role                     ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
_pdbx_modification_feature.ordinal                            1 
_pdbx_modification_feature.label_comp_id                      CYS 
_pdbx_modification_feature.label_asym_id                      C 
_pdbx_modification_feature.label_seq_id                       22 
_pdbx_modification_feature.label_alt_id                       ? 
_pdbx_modification_feature.modified_residue_label_comp_id     CYS 
_pdbx_modification_feature.modified_residue_label_asym_id     C 
_pdbx_modification_feature.modified_residue_label_seq_id      87 
_pdbx_modification_feature.modified_residue_label_alt_id      ? 
_pdbx_modification_feature.auth_comp_id                       CYS 
_pdbx_modification_feature.auth_asym_id                       L 
_pdbx_modification_feature.auth_seq_id                        26 
_pdbx_modification_feature.PDB_ins_code                       ? 
_pdbx_modification_feature.symmetry                           1_555 
_pdbx_modification_feature.modified_residue_auth_comp_id      CYS 
_pdbx_modification_feature.modified_residue_auth_asym_id      L 
_pdbx_modification_feature.modified_residue_auth_seq_id       91 
_pdbx_modification_feature.modified_residue_PDB_ins_code      ? 
_pdbx_modification_feature.modified_residue_symmetry          1_555 
_pdbx_modification_feature.comp_id_linking_atom               SG 
_pdbx_modification_feature.modified_residue_id_linking_atom   SG 
_pdbx_modification_feature.modified_residue_id                . 
_pdbx_modification_feature.ref_pcm_id                         . 
_pdbx_modification_feature.ref_comp_id                        . 
_pdbx_modification_feature.type                               None 
_pdbx_modification_feature.category                           'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 3 ? 
AA2 ? 8 ? 
AA3 ? 2 ? 
AA4 ? 2 ? 
AA5 ? 4 ? 
AA6 ? 3 ? 
AA7 ? 3 ? 
AA8 ? 2 ? 
AA9 ? 2 ? 
AB1 ? 5 ? 
AB2 ? 5 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA2 5 6 ? anti-parallel 
AA2 6 7 ? anti-parallel 
AA2 7 8 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB1 4 5 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB2 4 5 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 VAL A 6  ? LEU A 8  ? VAL A 6  LEU A 8   
AA1 2 LEU A 19 ? ASN A 27 ? LEU A 19 ASN A 27  
AA1 3 VAL A 32 ? GLN A 37 ? VAL A 32 GLN A 37  
AA2 1 VAL A 48 ? SER A 53 ? VAL A 48 SER A 53  
AA2 2 LYS A 63 ? GLN A 69 ? LYS A 63 GLN A 69  
AA2 3 ALA A 88 ? THR A 93 ? ALA A 88 THR A 93  
AA2 4 GLN B 87 ? PHE B 96 ? GLN B 87 PHE B 96  
AA2 5 TYR B 62 ? PRO B 71 ? TYR B 62 PRO B 71  
AA2 6 ARG B 47 ? SER B 51 ? ARG B 47 SER B 51  
AA2 7 VAL B 32 ? SER B 36 ? VAL B 32 SER B 36  
AA2 8 ASN B 22 ? ASN B 27 ? ASN B 22 ASN B 27  
AA3 1 THR A 72 ? CYS A 74 ? THR A 72 CYS A 74  
AA3 2 SER A 83 ? ARG A 86 ? SER A 83 ARG A 86  
AA4 1 THR B 7  ? ILE B 11 ? THR B 7  ILE B 11  
AA4 2 GLN B 17 ? VAL B 20 ? GLN B 17 VAL B 20  
AA5 1 MET C 3  ? GLN C 5  ? MET L 7  GLN L 9   
AA5 2 LEU C 20 ? ALA C 24 ? LEU L 24 ALA L 28  
AA5 3 ASP C 69 ? ILE C 74 ? ASP L 73 ILE L 78  
AA5 4 PHE C 61 ? SER C 66 ? PHE L 65 SER L 70  
AA6 1 ILE C 43 ? ARG C 45 ? ILE L 47 ARG L 49  
AA6 2 LEU C 32 ? GLN C 37 ? LEU L 36 GLN L 41  
AA6 3 ASP C 84 ? GLN C 89 ? ASP L 88 GLN L 93  
AA7 1 SER D 2  ? SER D 5  ? SER H 24 SER H 27  
AA7 2 SER D 59 ? MET D 62 ? SER H 81 MET H 84  
AA7 3 LEU D 51 ? ASP D 54 ? LEU H 73 ASP H 76  
AA8 1 TRP D 14 ? VAL D 18 ? TRP H 36 VAL H 40  
AA8 2 PHE D 76 ? SER D 80 ? PHE H 98 SER H 102 
AA9 1 GLY D 30 ? ARG D 31 ? GLY H 52 ARG H 53  
AA9 2 ASN D 40 ? TYR D 41 ? ASN H 62 TYR H 63  
AB1 1 ASN E 22 ? PRO E 23 ? ASN C 22 PRO C 23  
AB1 2 LEU E 35 ? SER E 36 ? LEU C 35 SER C 36  
AB1 3 ARG E 47 ? VAL E 52 ? ARG C 47 VAL C 52  
AB1 4 LYS E 63 ? CYS E 74 ? LYS C 63 CYS C 74  
AB1 5 SER E 83 ? ALA E 88 ? SER C 83 ALA C 88  
AB2 1 ASN E 22 ? PRO E 23 ? ASN C 22 PRO C 23  
AB2 2 LEU E 35 ? SER E 36 ? LEU C 35 SER C 36  
AB2 3 ARG E 47 ? VAL E 52 ? ARG C 47 VAL C 52  
AB2 4 LYS E 63 ? CYS E 74 ? LYS C 63 CYS C 74  
AB2 5 VAL E 92 ? SER E 95 ? VAL C 92 SER C 95  
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N VAL A 6  ? N VAL A 6  O LEU A 21 ? O LEU A 21  
AA1 2 3 N ASN A 22 ? N ASN A 22 O SER A 36 ? O SER A 36  
AA2 1 2 N THR A 49 ? N THR A 49 O LYS A 67 ? O LYS A 67  
AA2 2 3 N VAL A 66 ? N VAL A 66 O VAL A 92 ? O VAL A 92  
AA2 3 4 N THR A 93 ? N THR A 93 O ASP B 91 ? O ASP B 91  
AA2 4 5 O PHE B 94 ? O PHE B 94 N VAL B 64 ? N VAL B 64  
AA2 5 6 O LYS B 67 ? O LYS B 67 N THR B 49 ? N THR B 49  
AA2 6 7 O VAL B 50 ? O VAL B 50 N ALA B 33 ? N ALA B 33  
AA2 7 8 O SER B 36 ? O SER B 36 N ASN B 22 ? N ASN B 22  
AA3 1 2 N THR A 72 ? N THR A 72 O THR A 85 ? O THR A 85  
AA4 1 2 N ILE B 11 ? N ILE B 11 O GLN B 17 ? O GLN B 17  
AA5 1 2 N THR C 4  ? N THR L 8  O ARG C 23 ? O ARG L 27  
AA5 2 3 N CYS C 22 ? N CYS L 26 O TYR C 70 ? O TYR L 74  
AA5 3 4 O THR C 73 ? O THR L 77 N SER C 62 ? N SER L 66  
AA6 1 2 O LYS C 44 ? O LYS L 48 N GLN C 36 ? N GLN L 40  
AA6 2 3 N LEU C 35 ? N LEU L 39 O TYR C 86 ? O TYR L 90  
AA7 1 2 N SER D 2  ? N SER H 24 O MET D 62 ? O MET H 84  
AA7 2 3 O SER D 59 ? O SER H 81 N ASP D 54 ? N ASP H 76  
AA8 1 2 N TRP D 14 ? N TRP H 36 O SER D 80 ? O SER H 102 
AA9 1 2 N ARG D 31 ? N ARG H 53 O ASN D 40 ? O ASN H 62  
AB1 1 2 N ASN E 22 ? N ASN C 22 O SER E 36 ? O SER C 36  
AB1 2 3 N LEU E 35 ? N LEU C 35 O VAL E 48 ? O VAL C 48  
AB1 3 4 N THR E 49 ? N THR C 49 O LYS E 67 ? O LYS C 67  
AB1 4 5 N ASN E 70 ? N ASN C 70 O ALA E 88 ? O ALA C 88  
AB2 1 2 N ASN E 22 ? N ASN C 22 O SER E 36 ? O SER C 36  
AB2 2 3 N LEU E 35 ? N LEU C 35 O VAL E 48 ? O VAL C 48  
AB2 3 4 N THR E 49 ? N THR C 49 O LYS E 67 ? O LYS C 67  
AB2 4 5 N VAL E 64 ? N VAL C 64 O PHE E 94 ? O PHE C 94  
# 
_pdbx_entry_details.entry_id                   8W5G 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 NH2 L ARG 64 ? ? O   L SER 80 ? ? 2.13 
2 1 OG  C SER 36 ? ? OE2 C GLU 45 ? ? 2.14 
3 1 OG  L SER 68 ? ? OG  L SER 75 ? ? 2.18 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 PRO A 42  ? ? -62.55  4.76    
2  1 PRO A 130 ? ? -68.93  -175.67 
3  1 ASP B 14  ? ? 71.75   -5.54   
4  1 ALA B 40  ? ? -95.13  52.04   
5  1 SER L 23  ? ? 57.49   73.84   
6  1 THR L 46  ? ? -79.61  -166.97 
7  1 SER L 55  ? ? -143.65 28.12   
8  1 LEU L 57  ? ? 58.87   75.08   
9  1 THR L 83  ? ? 51.91   15.08   
10 1 TYR L 94  ? ? -141.66 19.77   
11 1 PHE H 67  ? ? -77.42  -164.59 
12 1 THR H 90  ? ? -68.45  -178.45 
13 1 TYR H 105 ? ? 55.12   -81.68  
14 1 ALA C 40  ? ? -123.35 -165.45 
# 
_pdbx_validate_peptide_omega.id               1 
_pdbx_validate_peptide_omega.PDB_model_num    1 
_pdbx_validate_peptide_omega.auth_comp_id_1   THR 
_pdbx_validate_peptide_omega.auth_asym_id_1   H 
_pdbx_validate_peptide_omega.auth_seq_id_1    90 
_pdbx_validate_peptide_omega.PDB_ins_code_1   ? 
_pdbx_validate_peptide_omega.label_alt_id_1   ? 
_pdbx_validate_peptide_omega.auth_comp_id_2   SER 
_pdbx_validate_peptide_omega.auth_asym_id_2   H 
_pdbx_validate_peptide_omega.auth_seq_id_2    91 
_pdbx_validate_peptide_omega.PDB_ins_code_2   ? 
_pdbx_validate_peptide_omega.label_alt_id_2   ? 
_pdbx_validate_peptide_omega.omega            -147.87 
# 
_pdbx_point_symmetry.entry_id             8W5G 
_pdbx_point_symmetry.Schoenflies_symbol   I 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8W5G 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8W5G 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  4 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               15049 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Complex of Qb-Ab7' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1,2,3 
# 
_em_imaging.entry_id                        8W5G 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1300 
_em_imaging.nominal_defocus_max             1800 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8W5G 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8W5G 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A TYR 132 ? A TYR 132 
2  1 Y 1 B ASN 77  ? B ASN 77  
3  1 Y 1 B GLY 78  ? B GLY 78  
4  1 Y 1 B SER 79  ? B SER 79  
5  1 Y 1 B CYS 80  ? B CYS 80  
6  1 Y 1 B TYR 132 ? B TYR 132 
7  1 Y 1 H GLN 42  ? D GLN 20  
8  1 Y 1 H ARG 43  ? D ARG 21  
9  1 Y 1 H PRO 44  ? D PRO 22  
10 1 Y 1 H GLY 45  ? D GLY 23  
11 1 Y 1 H LYS 46  ? D LYS 24  
12 1 Y 1 H GLY 47  ? D GLY 25  
13 1 Y 1 H LEU 48  ? D LEU 26  
14 1 Y 1 H GLU 49  ? D GLU 27  
15 1 Y 1 H TRP 50  ? D TRP 28  
16 1 Y 1 C SER 56  ? E SER 56  
17 1 Y 1 C ARG 57  ? E ARG 57  
18 1 Y 1 C ASN 58  ? E ASN 58  
19 1 Y 1 C ARG 59  ? E ARG 59  
20 1 Y 1 C LYS 60  ? E LYS 60  
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
ILE N    N N N 137 
ILE CA   C N S 138 
ILE C    C N N 139 
ILE O    O N N 140 
ILE CB   C N S 141 
ILE CG1  C N N 142 
ILE CG2  C N N 143 
ILE CD1  C N N 144 
ILE OXT  O N N 145 
ILE H    H N N 146 
ILE H2   H N N 147 
ILE HA   H N N 148 
ILE HB   H N N 149 
ILE HG12 H N N 150 
ILE HG13 H N N 151 
ILE HG21 H N N 152 
ILE HG22 H N N 153 
ILE HG23 H N N 154 
ILE HD11 H N N 155 
ILE HD12 H N N 156 
ILE HD13 H N N 157 
ILE HXT  H N N 158 
LEU N    N N N 159 
LEU CA   C N S 160 
LEU C    C N N 161 
LEU O    O N N 162 
LEU CB   C N N 163 
LEU CG   C N N 164 
LEU CD1  C N N 165 
LEU CD2  C N N 166 
LEU OXT  O N N 167 
LEU H    H N N 168 
LEU H2   H N N 169 
LEU HA   H N N 170 
LEU HB2  H N N 171 
LEU HB3  H N N 172 
LEU HG   H N N 173 
LEU HD11 H N N 174 
LEU HD12 H N N 175 
LEU HD13 H N N 176 
LEU HD21 H N N 177 
LEU HD22 H N N 178 
LEU HD23 H N N 179 
LEU HXT  H N N 180 
LYS N    N N N 181 
LYS CA   C N S 182 
LYS C    C N N 183 
LYS O    O N N 184 
LYS CB   C N N 185 
LYS CG   C N N 186 
LYS CD   C N N 187 
LYS CE   C N N 188 
LYS NZ   N N N 189 
LYS OXT  O N N 190 
LYS H    H N N 191 
LYS H2   H N N 192 
LYS HA   H N N 193 
LYS HB2  H N N 194 
LYS HB3  H N N 195 
LYS HG2  H N N 196 
LYS HG3  H N N 197 
LYS HD2  H N N 198 
LYS HD3  H N N 199 
LYS HE2  H N N 200 
LYS HE3  H N N 201 
LYS HZ1  H N N 202 
LYS HZ2  H N N 203 
LYS HZ3  H N N 204 
LYS HXT  H N N 205 
MET N    N N N 206 
MET CA   C N S 207 
MET C    C N N 208 
MET O    O N N 209 
MET CB   C N N 210 
MET CG   C N N 211 
MET SD   S N N 212 
MET CE   C N N 213 
MET OXT  O N N 214 
MET H    H N N 215 
MET H2   H N N 216 
MET HA   H N N 217 
MET HB2  H N N 218 
MET HB3  H N N 219 
MET HG2  H N N 220 
MET HG3  H N N 221 
MET HE1  H N N 222 
MET HE2  H N N 223 
MET HE3  H N N 224 
MET HXT  H N N 225 
PHE N    N N N 226 
PHE CA   C N S 227 
PHE C    C N N 228 
PHE O    O N N 229 
PHE CB   C N N 230 
PHE CG   C Y N 231 
PHE CD1  C Y N 232 
PHE CD2  C Y N 233 
PHE CE1  C Y N 234 
PHE CE2  C Y N 235 
PHE CZ   C Y N 236 
PHE OXT  O N N 237 
PHE H    H N N 238 
PHE H2   H N N 239 
PHE HA   H N N 240 
PHE HB2  H N N 241 
PHE HB3  H N N 242 
PHE HD1  H N N 243 
PHE HD2  H N N 244 
PHE HE1  H N N 245 
PHE HE2  H N N 246 
PHE HZ   H N N 247 
PHE HXT  H N N 248 
PRO N    N N N 249 
PRO CA   C N S 250 
PRO C    C N N 251 
PRO O    O N N 252 
PRO CB   C N N 253 
PRO CG   C N N 254 
PRO CD   C N N 255 
PRO OXT  O N N 256 
PRO H    H N N 257 
PRO HA   H N N 258 
PRO HB2  H N N 259 
PRO HB3  H N N 260 
PRO HG2  H N N 261 
PRO HG3  H N N 262 
PRO HD2  H N N 263 
PRO HD3  H N N 264 
PRO HXT  H N N 265 
SER N    N N N 266 
SER CA   C N S 267 
SER C    C N N 268 
SER O    O N N 269 
SER CB   C N N 270 
SER OG   O N N 271 
SER OXT  O N N 272 
SER H    H N N 273 
SER H2   H N N 274 
SER HA   H N N 275 
SER HB2  H N N 276 
SER HB3  H N N 277 
SER HG   H N N 278 
SER HXT  H N N 279 
THR N    N N N 280 
THR CA   C N S 281 
THR C    C N N 282 
THR O    O N N 283 
THR CB   C N R 284 
THR OG1  O N N 285 
THR CG2  C N N 286 
THR OXT  O N N 287 
THR H    H N N 288 
THR H2   H N N 289 
THR HA   H N N 290 
THR HB   H N N 291 
THR HG1  H N N 292 
THR HG21 H N N 293 
THR HG22 H N N 294 
THR HG23 H N N 295 
THR HXT  H N N 296 
TRP N    N N N 297 
TRP CA   C N S 298 
TRP C    C N N 299 
TRP O    O N N 300 
TRP CB   C N N 301 
TRP CG   C Y N 302 
TRP CD1  C Y N 303 
TRP CD2  C Y N 304 
TRP NE1  N Y N 305 
TRP CE2  C Y N 306 
TRP CE3  C Y N 307 
TRP CZ2  C Y N 308 
TRP CZ3  C Y N 309 
TRP CH2  C Y N 310 
TRP OXT  O N N 311 
TRP H    H N N 312 
TRP H2   H N N 313 
TRP HA   H N N 314 
TRP HB2  H N N 315 
TRP HB3  H N N 316 
TRP HD1  H N N 317 
TRP HE1  H N N 318 
TRP HE3  H N N 319 
TRP HZ2  H N N 320 
TRP HZ3  H N N 321 
TRP HH2  H N N 322 
TRP HXT  H N N 323 
TYR N    N N N 324 
TYR CA   C N S 325 
TYR C    C N N 326 
TYR O    O N N 327 
TYR CB   C N N 328 
TYR CG   C Y N 329 
TYR CD1  C Y N 330 
TYR CD2  C Y N 331 
TYR CE1  C Y N 332 
TYR CE2  C Y N 333 
TYR CZ   C Y N 334 
TYR OH   O N N 335 
TYR OXT  O N N 336 
TYR H    H N N 337 
TYR H2   H N N 338 
TYR HA   H N N 339 
TYR HB2  H N N 340 
TYR HB3  H N N 341 
TYR HD1  H N N 342 
TYR HD2  H N N 343 
TYR HE1  H N N 344 
TYR HE2  H N N 345 
TYR HH   H N N 346 
TYR HXT  H N N 347 
VAL N    N N N 348 
VAL CA   C N S 349 
VAL C    C N N 350 
VAL O    O N N 351 
VAL CB   C N N 352 
VAL CG1  C N N 353 
VAL CG2  C N N 354 
VAL OXT  O N N 355 
VAL H    H N N 356 
VAL H2   H N N 357 
VAL HA   H N N 358 
VAL HB   H N N 359 
VAL HG11 H N N 360 
VAL HG12 H N N 361 
VAL HG13 H N N 362 
VAL HG21 H N N 363 
VAL HG22 H N N 364 
VAL HG23 H N N 365 
VAL HXT  H N N 366 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
ILE N   CA   sing N N 129 
ILE N   H    sing N N 130 
ILE N   H2   sing N N 131 
ILE CA  C    sing N N 132 
ILE CA  CB   sing N N 133 
ILE CA  HA   sing N N 134 
ILE C   O    doub N N 135 
ILE C   OXT  sing N N 136 
ILE CB  CG1  sing N N 137 
ILE CB  CG2  sing N N 138 
ILE CB  HB   sing N N 139 
ILE CG1 CD1  sing N N 140 
ILE CG1 HG12 sing N N 141 
ILE CG1 HG13 sing N N 142 
ILE CG2 HG21 sing N N 143 
ILE CG2 HG22 sing N N 144 
ILE CG2 HG23 sing N N 145 
ILE CD1 HD11 sing N N 146 
ILE CD1 HD12 sing N N 147 
ILE CD1 HD13 sing N N 148 
ILE OXT HXT  sing N N 149 
LEU N   CA   sing N N 150 
LEU N   H    sing N N 151 
LEU N   H2   sing N N 152 
LEU CA  C    sing N N 153 
LEU CA  CB   sing N N 154 
LEU CA  HA   sing N N 155 
LEU C   O    doub N N 156 
LEU C   OXT  sing N N 157 
LEU CB  CG   sing N N 158 
LEU CB  HB2  sing N N 159 
LEU CB  HB3  sing N N 160 
LEU CG  CD1  sing N N 161 
LEU CG  CD2  sing N N 162 
LEU CG  HG   sing N N 163 
LEU CD1 HD11 sing N N 164 
LEU CD1 HD12 sing N N 165 
LEU CD1 HD13 sing N N 166 
LEU CD2 HD21 sing N N 167 
LEU CD2 HD22 sing N N 168 
LEU CD2 HD23 sing N N 169 
LEU OXT HXT  sing N N 170 
LYS N   CA   sing N N 171 
LYS N   H    sing N N 172 
LYS N   H2   sing N N 173 
LYS CA  C    sing N N 174 
LYS CA  CB   sing N N 175 
LYS CA  HA   sing N N 176 
LYS C   O    doub N N 177 
LYS C   OXT  sing N N 178 
LYS CB  CG   sing N N 179 
LYS CB  HB2  sing N N 180 
LYS CB  HB3  sing N N 181 
LYS CG  CD   sing N N 182 
LYS CG  HG2  sing N N 183 
LYS CG  HG3  sing N N 184 
LYS CD  CE   sing N N 185 
LYS CD  HD2  sing N N 186 
LYS CD  HD3  sing N N 187 
LYS CE  NZ   sing N N 188 
LYS CE  HE2  sing N N 189 
LYS CE  HE3  sing N N 190 
LYS NZ  HZ1  sing N N 191 
LYS NZ  HZ2  sing N N 192 
LYS NZ  HZ3  sing N N 193 
LYS OXT HXT  sing N N 194 
MET N   CA   sing N N 195 
MET N   H    sing N N 196 
MET N   H2   sing N N 197 
MET CA  C    sing N N 198 
MET CA  CB   sing N N 199 
MET CA  HA   sing N N 200 
MET C   O    doub N N 201 
MET C   OXT  sing N N 202 
MET CB  CG   sing N N 203 
MET CB  HB2  sing N N 204 
MET CB  HB3  sing N N 205 
MET CG  SD   sing N N 206 
MET CG  HG2  sing N N 207 
MET CG  HG3  sing N N 208 
MET SD  CE   sing N N 209 
MET CE  HE1  sing N N 210 
MET CE  HE2  sing N N 211 
MET CE  HE3  sing N N 212 
MET OXT HXT  sing N N 213 
PHE N   CA   sing N N 214 
PHE N   H    sing N N 215 
PHE N   H2   sing N N 216 
PHE CA  C    sing N N 217 
PHE CA  CB   sing N N 218 
PHE CA  HA   sing N N 219 
PHE C   O    doub N N 220 
PHE C   OXT  sing N N 221 
PHE CB  CG   sing N N 222 
PHE CB  HB2  sing N N 223 
PHE CB  HB3  sing N N 224 
PHE CG  CD1  doub Y N 225 
PHE CG  CD2  sing Y N 226 
PHE CD1 CE1  sing Y N 227 
PHE CD1 HD1  sing N N 228 
PHE CD2 CE2  doub Y N 229 
PHE CD2 HD2  sing N N 230 
PHE CE1 CZ   doub Y N 231 
PHE CE1 HE1  sing N N 232 
PHE CE2 CZ   sing Y N 233 
PHE CE2 HE2  sing N N 234 
PHE CZ  HZ   sing N N 235 
PHE OXT HXT  sing N N 236 
PRO N   CA   sing N N 237 
PRO N   CD   sing N N 238 
PRO N   H    sing N N 239 
PRO CA  C    sing N N 240 
PRO CA  CB   sing N N 241 
PRO CA  HA   sing N N 242 
PRO C   O    doub N N 243 
PRO C   OXT  sing N N 244 
PRO CB  CG   sing N N 245 
PRO CB  HB2  sing N N 246 
PRO CB  HB3  sing N N 247 
PRO CG  CD   sing N N 248 
PRO CG  HG2  sing N N 249 
PRO CG  HG3  sing N N 250 
PRO CD  HD2  sing N N 251 
PRO CD  HD3  sing N N 252 
PRO OXT HXT  sing N N 253 
SER N   CA   sing N N 254 
SER N   H    sing N N 255 
SER N   H2   sing N N 256 
SER CA  C    sing N N 257 
SER CA  CB   sing N N 258 
SER CA  HA   sing N N 259 
SER C   O    doub N N 260 
SER C   OXT  sing N N 261 
SER CB  OG   sing N N 262 
SER CB  HB2  sing N N 263 
SER CB  HB3  sing N N 264 
SER OG  HG   sing N N 265 
SER OXT HXT  sing N N 266 
THR N   CA   sing N N 267 
THR N   H    sing N N 268 
THR N   H2   sing N N 269 
THR CA  C    sing N N 270 
THR CA  CB   sing N N 271 
THR CA  HA   sing N N 272 
THR C   O    doub N N 273 
THR C   OXT  sing N N 274 
THR CB  OG1  sing N N 275 
THR CB  CG2  sing N N 276 
THR CB  HB   sing N N 277 
THR OG1 HG1  sing N N 278 
THR CG2 HG21 sing N N 279 
THR CG2 HG22 sing N N 280 
THR CG2 HG23 sing N N 281 
THR OXT HXT  sing N N 282 
TRP N   CA   sing N N 283 
TRP N   H    sing N N 284 
TRP N   H2   sing N N 285 
TRP CA  C    sing N N 286 
TRP CA  CB   sing N N 287 
TRP CA  HA   sing N N 288 
TRP C   O    doub N N 289 
TRP C   OXT  sing N N 290 
TRP CB  CG   sing N N 291 
TRP CB  HB2  sing N N 292 
TRP CB  HB3  sing N N 293 
TRP CG  CD1  doub Y N 294 
TRP CG  CD2  sing Y N 295 
TRP CD1 NE1  sing Y N 296 
TRP CD1 HD1  sing N N 297 
TRP CD2 CE2  doub Y N 298 
TRP CD2 CE3  sing Y N 299 
TRP NE1 CE2  sing Y N 300 
TRP NE1 HE1  sing N N 301 
TRP CE2 CZ2  sing Y N 302 
TRP CE3 CZ3  doub Y N 303 
TRP CE3 HE3  sing N N 304 
TRP CZ2 CH2  doub Y N 305 
TRP CZ2 HZ2  sing N N 306 
TRP CZ3 CH2  sing Y N 307 
TRP CZ3 HZ3  sing N N 308 
TRP CH2 HH2  sing N N 309 
TRP OXT HXT  sing N N 310 
TYR N   CA   sing N N 311 
TYR N   H    sing N N 312 
TYR N   H2   sing N N 313 
TYR CA  C    sing N N 314 
TYR CA  CB   sing N N 315 
TYR CA  HA   sing N N 316 
TYR C   O    doub N N 317 
TYR C   OXT  sing N N 318 
TYR CB  CG   sing N N 319 
TYR CB  HB2  sing N N 320 
TYR CB  HB3  sing N N 321 
TYR CG  CD1  doub Y N 322 
TYR CG  CD2  sing Y N 323 
TYR CD1 CE1  sing Y N 324 
TYR CD1 HD1  sing N N 325 
TYR CD2 CE2  doub Y N 326 
TYR CD2 HD2  sing N N 327 
TYR CE1 CZ   doub Y N 328 
TYR CE1 HE1  sing N N 329 
TYR CE2 CZ   sing Y N 330 
TYR CE2 HE2  sing N N 331 
TYR CZ  OH   sing N N 332 
TYR OH  HH   sing N N 333 
TYR OXT HXT  sing N N 334 
VAL N   CA   sing N N 335 
VAL N   H    sing N N 336 
VAL N   H2   sing N N 337 
VAL CA  C    sing N N 338 
VAL CA  CB   sing N N 339 
VAL CA  HA   sing N N 340 
VAL C   O    doub N N 341 
VAL C   OXT  sing N N 342 
VAL CB  CG1  sing N N 343 
VAL CB  CG2  sing N N 344 
VAL CB  HB   sing N N 345 
VAL CG1 HG11 sing N N 346 
VAL CG1 HG12 sing N N 347 
VAL CG1 HG13 sing N N 348 
VAL CG2 HG21 sing N N 349 
VAL CG2 HG22 sing N N 350 
VAL CG2 HG23 sing N N 351 
VAL OXT HXT  sing N N 352 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-08-26 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8W5G 
_em_admin.last_update        2025-02-26 
_em_admin.map_release_date   2025-02-26 
_em_admin.title              'Cryo-EM structure of Qb-Ab7' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          10090 
_em_entity_assembly_naturalsource.organism             'Mus musculus' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         60 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K2 SUMMIT (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ?      ?            
'MODEL REFINEMENT'         ? 2  ? ? ? PHENIX 1.19.2_4158: 
'IMAGE ACQUISITION'        ? 3  ? ? 1 ?      ?            
MASKING                    ? 4  ? ? ? ?      ?            
'CTF CORRECTION'           ? 5  1 ? ? ?      ?            
'LAYERLINE INDEXING'       ? 6  ? ? ? ?      ?            
'DIFFRACTION INDEXING'     ? 7  ? ? ? ?      ?            
'MODEL FITTING'            ? 8  ? ? ? ?      ?            
OTHER                      ? 9  ? ? ? ?      ?            
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ?      ?            
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ?      ?            
CLASSIFICATION             ? 12 1 ? ? ?      ?            
RECONSTRUCTION             ? 13 1 ? ? ?      ?            
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Natural Science Foundation of China (NSFC)' China 81991495    1 
'National Natural Science Foundation of China (NSFC)' China 32241029    2 
'Chinese Academy of Sciences'                         China XDB29050600 3 
'Chinese Academy of Sciences'                         China XDB37010100 4 
# 
_atom_sites.entry_id                    8W5G 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . ALA A 1 1   ? 265.129 305.257 400.330 1.00 76.35  ? 1   ALA A N   1 
ATOM 2    C CA  . ALA A 1 1   ? 266.250 304.577 400.966 1.00 76.35  ? 1   ALA A CA  1 
ATOM 3    C C   . ALA A 1 1   ? 266.225 303.086 400.655 1.00 76.35  ? 1   ALA A C   1 
ATOM 4    O O   . ALA A 1 1   ? 265.939 302.680 399.530 1.00 76.35  ? 1   ALA A O   1 
ATOM 5    C CB  . ALA A 1 1   ? 266.227 304.806 402.467 1.00 76.35  ? 1   ALA A CB  1 
ATOM 6    N N   . LYS A 1 2   ? 266.529 302.276 401.664 1.00 78.44  ? 2   LYS A N   1 
ATOM 7    C CA  . LYS A 1 2   ? 266.520 300.832 401.499 1.00 78.44  ? 2   LYS A CA  1 
ATOM 8    C C   . LYS A 1 2   ? 265.085 300.332 401.354 1.00 78.44  ? 2   LYS A C   1 
ATOM 9    O O   . LYS A 1 2   ? 264.131 300.986 401.779 1.00 78.44  ? 2   LYS A O   1 
ATOM 10   C CB  . LYS A 1 2   ? 267.216 300.168 402.692 1.00 78.44  ? 2   LYS A CB  1 
ATOM 11   C CG  . LYS A 1 2   ? 267.169 298.645 402.727 1.00 78.44  ? 2   LYS A CG  1 
ATOM 12   C CD  . LYS A 1 2   ? 268.040 298.071 403.838 1.00 78.44  ? 2   LYS A CD  1 
ATOM 13   C CE  . LYS A 1 2   ? 268.120 299.002 405.038 1.00 78.44  ? 2   LYS A CE  1 
ATOM 14   N NZ  . LYS A 1 2   ? 269.198 298.598 405.982 1.00 78.44  ? 2   LYS A NZ  1 
ATOM 15   N N   . LEU A 1 3   ? 264.935 299.180 400.705 1.00 81.91  ? 3   LEU A N   1 
ATOM 16   C CA  . LEU A 1 3   ? 263.636 298.534 400.583 1.00 81.91  ? 3   LEU A CA  1 
ATOM 17   C C   . LEU A 1 3   ? 263.301 297.766 401.854 1.00 81.91  ? 3   LEU A C   1 
ATOM 18   O O   . LEU A 1 3   ? 264.143 297.049 402.403 1.00 81.91  ? 3   LEU A O   1 
ATOM 19   C CB  . LEU A 1 3   ? 263.628 297.578 399.390 1.00 81.91  ? 3   LEU A CB  1 
ATOM 20   C CG  . LEU A 1 3   ? 263.161 298.104 398.035 1.00 81.91  ? 3   LEU A CG  1 
ATOM 21   C CD1 . LEU A 1 3   ? 261.714 298.534 398.114 1.00 81.91  ? 3   LEU A CD1 1 
ATOM 22   C CD2 . LEU A 1 3   ? 264.037 299.246 397.564 1.00 81.91  ? 3   LEU A CD2 1 
ATOM 23   N N   . GLU A 1 4   ? 262.065 297.918 402.324 1.00 85.76  ? 4   GLU A N   1 
ATOM 24   C CA  . GLU A 1 4   ? 261.552 297.114 403.429 1.00 85.76  ? 4   GLU A CA  1 
ATOM 25   C C   . GLU A 1 4   ? 260.097 296.777 403.133 1.00 85.76  ? 4   GLU A C   1 
ATOM 26   O O   . GLU A 1 4   ? 259.608 296.962 402.015 1.00 85.76  ? 4   GLU A O   1 
ATOM 27   C CB  . GLU A 1 4   ? 261.675 297.830 404.783 1.00 85.76  ? 4   GLU A CB  1 
ATOM 28   C CG  . GLU A 1 4   ? 263.090 298.057 405.279 1.00 85.76  ? 4   GLU A CG  1 
ATOM 29   C CD  . GLU A 1 4   ? 263.712 299.291 404.673 1.00 85.76  ? 4   GLU A CD  1 
ATOM 30   O OE1 . GLU A 1 4   ? 263.003 299.990 403.922 1.00 85.76  ? 4   GLU A OE1 1 
ATOM 31   O OE2 . GLU A 1 4   ? 264.900 299.562 404.943 1.00 85.76  ? 4   GLU A OE2 1 
ATOM 32   N N   . THR A 1 5   ? 259.404 296.270 404.148 1.00 87.03  ? 5   THR A N   1 
ATOM 33   C CA  . THR A 1 5   ? 257.969 296.062 404.042 1.00 87.03  ? 5   THR A CA  1 
ATOM 34   C C   . THR A 1 5   ? 257.248 297.397 404.163 1.00 87.03  ? 5   THR A C   1 
ATOM 35   O O   . THR A 1 5   ? 257.541 298.192 405.060 1.00 87.03  ? 5   THR A O   1 
ATOM 36   C CB  . THR A 1 5   ? 257.487 295.104 405.127 1.00 87.03  ? 5   THR A CB  1 
ATOM 37   O OG1 . THR A 1 5   ? 257.524 295.766 406.397 1.00 87.03  ? 5   THR A OG1 1 
ATOM 38   C CG2 . THR A 1 5   ? 258.376 293.874 405.181 1.00 87.03  ? 5   THR A CG2 1 
ATOM 39   N N   . VAL A 1 6   ? 256.305 297.643 403.260 1.00 91.21  ? 6   VAL A N   1 
ATOM 40   C CA  . VAL A 1 6   ? 255.532 298.878 403.243 1.00 91.21  ? 6   VAL A CA  1 
ATOM 41   C C   . VAL A 1 6   ? 254.095 298.532 403.598 1.00 91.21  ? 6   VAL A C   1 
ATOM 42   O O   . VAL A 1 6   ? 253.466 297.704 402.928 1.00 91.21  ? 6   VAL A O   1 
ATOM 43   C CB  . VAL A 1 6   ? 255.607 299.581 401.881 1.00 91.21  ? 6   VAL A CB  1 
ATOM 44   C CG1 . VAL A 1 6   ? 254.648 300.754 401.844 1.00 91.21  ? 6   VAL A CG1 1 
ATOM 45   C CG2 . VAL A 1 6   ? 257.026 300.040 401.603 1.00 91.21  ? 6   VAL A CG2 1 
ATOM 46   N N   . THR A 1 7   ? 253.580 299.161 404.649 1.00 95.54  ? 7   THR A N   1 
ATOM 47   C CA  . THR A 1 7   ? 252.225 298.926 405.125 1.00 95.54  ? 7   THR A CA  1 
ATOM 48   C C   . THR A 1 7   ? 251.359 300.133 404.798 1.00 95.54  ? 7   THR A C   1 
ATOM 49   O O   . THR A 1 7   ? 251.781 301.277 404.994 1.00 95.54  ? 7   THR A O   1 
ATOM 50   C CB  . THR A 1 7   ? 252.207 298.657 406.630 1.00 95.54  ? 7   THR A CB  1 
ATOM 51   O OG1 . THR A 1 7   ? 252.771 299.776 407.324 1.00 95.54  ? 7   THR A OG1 1 
ATOM 52   C CG2 . THR A 1 7   ? 253.009 297.410 406.956 1.00 95.54  ? 7   THR A CG2 1 
ATOM 53   N N   . LEU A 1 8   ? 250.156 299.875 404.295 1.00 90.95  ? 8   LEU A N   1 
ATOM 54   C CA  . LEU A 1 8   ? 249.208 300.920 403.934 1.00 90.95  ? 8   LEU A CA  1 
ATOM 55   C C   . LEU A 1 8   ? 247.962 300.762 404.792 1.00 90.95  ? 8   LEU A C   1 
ATOM 56   O O   . LEU A 1 8   ? 247.363 299.682 404.829 1.00 90.95  ? 8   LEU A O   1 
ATOM 57   C CB  . LEU A 1 8   ? 248.863 300.844 402.448 1.00 90.95  ? 8   LEU A CB  1 
ATOM 58   C CG  . LEU A 1 8   ? 250.069 301.021 401.529 1.00 90.95  ? 8   LEU A CG  1 
ATOM 59   C CD1 . LEU A 1 8   ? 249.716 300.653 400.101 1.00 90.95  ? 8   LEU A CD1 1 
ATOM 60   C CD2 . LEU A 1 8   ? 250.581 302.445 401.608 1.00 90.95  ? 8   LEU A CD2 1 
ATOM 61   N N   . GLY A 1 9   ? 247.575 301.835 405.477 1.00 87.05  ? 9   GLY A N   1 
ATOM 62   C CA  . GLY A 1 9   ? 246.441 301.818 406.382 1.00 87.05  ? 9   GLY A CA  1 
ATOM 63   C C   . GLY A 1 9   ? 245.322 302.715 405.890 1.00 87.05  ? 9   GLY A C   1 
ATOM 64   O O   . GLY A 1 9   ? 245.557 303.672 405.149 1.00 87.05  ? 9   GLY A O   1 
ATOM 65   N N   . ASN A 1 10  ? 244.096 302.391 406.304 1.00 89.10  ? 10  ASN A N   1 
ATOM 66   C CA  . ASN A 1 10  ? 242.906 303.174 405.975 1.00 89.10  ? 10  ASN A CA  1 
ATOM 67   C C   . ASN A 1 10  ? 242.735 303.303 404.460 1.00 89.10  ? 10  ASN A C   1 
ATOM 68   O O   . ASN A 1 10  ? 242.795 304.389 403.883 1.00 89.10  ? 10  ASN A O   1 
ATOM 69   C CB  . ASN A 1 10  ? 242.953 304.546 406.653 1.00 89.10  ? 10  ASN A CB  1 
ATOM 70   C CG  . ASN A 1 10  ? 242.896 304.445 408.162 1.00 89.10  ? 10  ASN A CG  1 
ATOM 71   O OD1 . ASN A 1 10  ? 243.467 303.530 408.754 1.00 89.10  ? 10  ASN A OD1 1 
ATOM 72   N ND2 . ASN A 1 10  ? 242.202 305.384 408.793 1.00 89.10  ? 10  ASN A ND2 1 
ATOM 73   N N   . ILE A 1 11  ? 242.521 302.157 403.825 1.00 89.64  ? 11  ILE A N   1 
ATOM 74   C CA  . ILE A 1 11  ? 242.411 302.070 402.380 1.00 89.64  ? 11  ILE A CA  1 
ATOM 75   C C   . ILE A 1 11  ? 240.960 301.724 402.039 1.00 89.64  ? 11  ILE A C   1 
ATOM 76   O O   . ILE A 1 11  ? 240.180 301.307 402.895 1.00 89.64  ? 11  ILE A O   1 
ATOM 77   C CB  . ILE A 1 11  ? 243.411 301.043 401.806 1.00 89.64  ? 11  ILE A CB  1 
ATOM 78   C CG1 . ILE A 1 11  ? 244.827 301.448 402.194 1.00 89.64  ? 11  ILE A CG1 1 
ATOM 79   C CG2 . ILE A 1 11  ? 243.383 300.997 400.296 1.00 89.64  ? 11  ILE A CG2 1 
ATOM 80   C CD1 . ILE A 1 11  ? 245.227 302.791 401.656 1.00 89.64  ? 11  ILE A CD1 1 
ATOM 81   N N   . GLY A 1 12  ? 240.595 301.926 400.775 1.00 89.72  ? 12  GLY A N   1 
ATOM 82   C CA  . GLY A 1 12  ? 239.257 301.641 400.306 1.00 89.72  ? 12  GLY A CA  1 
ATOM 83   C C   . GLY A 1 12  ? 238.294 302.782 400.569 1.00 89.72  ? 12  GLY A C   1 
ATOM 84   O O   . GLY A 1 12  ? 238.567 303.719 401.322 1.00 89.72  ? 12  GLY A O   1 
ATOM 85   N N   . LYS A 1 13  ? 237.131 302.696 399.917 1.00 91.79  ? 13  LYS A N   1 
ATOM 86   C CA  . LYS A 1 13  ? 236.116 303.729 400.092 1.00 91.79  ? 13  LYS A CA  1 
ATOM 87   C C   . LYS A 1 13  ? 235.634 303.786 401.534 1.00 91.79  ? 13  LYS A C   1 
ATOM 88   O O   . LYS A 1 13  ? 235.478 304.873 402.103 1.00 91.79  ? 13  LYS A O   1 
ATOM 89   C CB  . LYS A 1 13  ? 234.941 303.482 399.147 1.00 91.79  ? 13  LYS A CB  1 
ATOM 90   C CG  . LYS A 1 13  ? 234.491 302.036 399.074 1.00 91.79  ? 13  LYS A CG  1 
ATOM 91   C CD  . LYS A 1 13  ? 233.462 301.843 397.974 1.00 91.79  ? 13  LYS A CD  1 
ATOM 92   C CE  . LYS A 1 13  ? 234.119 301.761 396.610 1.00 91.79  ? 13  LYS A CE  1 
ATOM 93   N NZ  . LYS A 1 13  ? 233.128 301.869 395.506 1.00 91.79  ? 13  LYS A NZ  1 
ATOM 94   N N   . ASP A 1 14  ? 235.400 302.624 402.146 1.00 101.77 ? 14  ASP A N   1 
ATOM 95   C CA  . ASP A 1 14  ? 234.949 302.579 403.529 1.00 101.77 ? 14  ASP A CA  1 
ATOM 96   C C   . ASP A 1 14  ? 236.020 303.018 404.517 1.00 101.77 ? 14  ASP A C   1 
ATOM 97   O O   . ASP A 1 14  ? 235.694 303.285 405.678 1.00 101.77 ? 14  ASP A O   1 
ATOM 98   C CB  . ASP A 1 14  ? 234.463 301.168 403.873 1.00 101.77 ? 14  ASP A CB  1 
ATOM 99   C CG  . ASP A 1 14  ? 235.564 300.123 403.774 1.00 101.77 ? 14  ASP A CG  1 
ATOM 100  O OD1 . ASP A 1 14  ? 236.704 300.472 403.400 1.00 101.77 ? 14  ASP A OD1 1 
ATOM 101  O OD2 . ASP A 1 14  ? 235.287 298.944 404.076 1.00 101.77 ? 14  ASP A OD2 1 
ATOM 102  N N   . GLY A 1 15  ? 237.277 303.098 404.091 1.00 98.27  ? 15  GLY A N   1 
ATOM 103  C CA  . GLY A 1 15  ? 238.356 303.476 404.974 1.00 98.27  ? 15  GLY A CA  1 
ATOM 104  C C   . GLY A 1 15  ? 238.897 302.363 405.842 1.00 98.27  ? 15  GLY A C   1 
ATOM 105  O O   . GLY A 1 15  ? 239.796 302.618 406.653 1.00 98.27  ? 15  GLY A O   1 
ATOM 106  N N   . LYS A 1 16  ? 238.383 301.143 405.709 1.00 92.83  ? 16  LYS A N   1 
ATOM 107  C CA  . LYS A 1 16  ? 238.856 299.997 406.483 1.00 92.83  ? 16  LYS A CA  1 
ATOM 108  C C   . LYS A 1 16  ? 239.325 298.920 405.512 1.00 92.83  ? 16  LYS A C   1 
ATOM 109  O O   . LYS A 1 16  ? 238.584 297.995 405.175 1.00 92.83  ? 16  LYS A O   1 
ATOM 110  C CB  . LYS A 1 16  ? 237.761 299.482 407.417 1.00 92.83  ? 16  LYS A CB  1 
ATOM 111  C CG  . LYS A 1 16  ? 237.985 299.832 408.878 1.00 92.83  ? 16  LYS A CG  1 
ATOM 112  C CD  . LYS A 1 16  ? 238.837 298.779 409.569 1.00 92.83  ? 16  LYS A CD  1 
ATOM 113  C CE  . LYS A 1 16  ? 239.045 299.105 411.039 1.00 92.83  ? 16  LYS A CE  1 
ATOM 114  N NZ  . LYS A 1 16  ? 239.732 297.999 411.762 1.00 92.83  ? 16  LYS A NZ  1 
ATOM 115  N N   . GLN A 1 17  ? 240.576 299.042 405.075 1.00 95.29  ? 17  GLN A N   1 
ATOM 116  C CA  . GLN A 1 17  ? 241.246 298.032 404.270 1.00 95.29  ? 17  GLN A CA  1 
ATOM 117  C C   . GLN A 1 17  ? 242.718 298.048 404.640 1.00 95.29  ? 17  GLN A C   1 
ATOM 118  O O   . GLN A 1 17  ? 243.232 299.064 405.114 1.00 95.29  ? 17  GLN A O   1 
ATOM 119  C CB  . GLN A 1 17  ? 241.088 298.275 402.763 1.00 95.29  ? 17  GLN A CB  1 
ATOM 120  C CG  . GLN A 1 17  ? 239.668 298.193 402.239 1.00 95.29  ? 17  GLN A CG  1 
ATOM 121  C CD  . GLN A 1 17  ? 239.098 296.797 402.345 1.00 95.29  ? 17  GLN A CD  1 
ATOM 122  O OE1 . GLN A 1 17  ? 239.797 295.811 402.119 1.00 95.29  ? 17  GLN A OE1 1 
ATOM 123  N NE2 . GLN A 1 17  ? 237.821 296.704 402.694 1.00 95.29  ? 17  GLN A NE2 1 
ATOM 124  N N   . THR A 1 18  ? 243.389 296.923 404.429 1.00 105.18 ? 18  THR A N   1 
ATOM 125  C CA  . THR A 1 18  ? 244.808 296.811 404.713 1.00 105.18 ? 18  THR A CA  1 
ATOM 126  C C   . THR A 1 18  ? 245.526 296.210 403.514 1.00 105.18 ? 18  THR A C   1 
ATOM 127  O O   . THR A 1 18  ? 245.044 295.267 402.881 1.00 105.18 ? 18  THR A O   1 
ATOM 128  C CB  . THR A 1 18  ? 245.057 295.959 405.965 1.00 105.18 ? 18  THR A CB  1 
ATOM 129  O OG1 . THR A 1 18  ? 244.371 296.540 407.080 1.00 105.18 ? 18  THR A OG1 1 
ATOM 130  C CG2 . THR A 1 18  ? 246.543 295.890 406.282 1.00 105.18 ? 18  THR A CG2 1 
ATOM 131  N N   . LEU A 1 19  ? 246.688 296.776 403.203 1.00 90.14  ? 19  LEU A N   1 
ATOM 132  C CA  . LEU A 1 19  ? 247.535 296.249 402.146 1.00 90.14  ? 19  LEU A CA  1 
ATOM 133  C C   . LEU A 1 19  ? 248.968 296.215 402.651 1.00 90.14  ? 19  LEU A C   1 
ATOM 134  O O   . LEU A 1 19  ? 249.443 297.182 403.252 1.00 90.14  ? 19  LEU A O   1 
ATOM 135  C CB  . LEU A 1 19  ? 247.436 297.089 400.871 1.00 90.14  ? 19  LEU A CB  1 
ATOM 136  C CG  . LEU A 1 19  ? 248.115 296.481 399.646 1.00 90.14  ? 19  LEU A CG  1 
ATOM 137  C CD1 . LEU A 1 19  ? 247.520 295.121 399.336 1.00 90.14  ? 19  LEU A CD1 1 
ATOM 138  C CD2 . LEU A 1 19  ? 247.991 297.408 398.451 1.00 90.14  ? 19  LEU A CD2 1 
ATOM 139  N N   . VAL A 1 20  ? 249.647 295.098 402.410 1.00 87.62  ? 20  VAL A N   1 
ATOM 140  C CA  . VAL A 1 20  ? 251.020 294.888 402.851 1.00 87.62  ? 20  VAL A CA  1 
ATOM 141  C C   . VAL A 1 20  ? 251.872 294.603 401.625 1.00 87.62  ? 20  VAL A C   1 
ATOM 142  O O   . VAL A 1 20  ? 251.501 293.777 400.784 1.00 87.62  ? 20  VAL A O   1 
ATOM 143  C CB  . VAL A 1 20  ? 251.124 293.738 403.868 1.00 87.62  ? 20  VAL A CB  1 
ATOM 144  C CG1 . VAL A 1 20  ? 252.478 293.762 404.550 1.00 87.62  ? 20  VAL A CG1 1 
ATOM 145  C CG2 . VAL A 1 20  ? 250.006 293.831 404.892 1.00 87.62  ? 20  VAL A CG2 1 
ATOM 146  N N   . LEU A 1 21  ? 253.010 295.283 401.526 1.00 82.92  ? 21  LEU A N   1 
ATOM 147  C CA  . LEU A 1 21  ? 253.897 295.166 400.377 1.00 82.92  ? 21  LEU A CA  1 
ATOM 148  C C   . LEU A 1 21  ? 255.244 294.621 400.823 1.00 82.92  ? 21  LEU A C   1 
ATOM 149  O O   . LEU A 1 21  ? 255.806 295.083 401.821 1.00 82.92  ? 21  LEU A O   1 
ATOM 150  C CB  . LEU A 1 21  ? 254.084 296.516 399.679 1.00 82.92  ? 21  LEU A CB  1 
ATOM 151  C CG  . LEU A 1 21  ? 253.040 296.942 398.643 1.00 82.92  ? 21  LEU A CG  1 
ATOM 152  C CD1 . LEU A 1 21  ? 253.019 295.964 397.481 1.00 82.92  ? 21  LEU A CD1 1 
ATOM 153  C CD2 . LEU A 1 21  ? 251.656 297.092 399.248 1.00 82.92  ? 21  LEU A CD2 1 
ATOM 154  N N   . ASN A 1 22  ? 255.760 293.633 400.081 1.00 77.91  ? 22  ASN A N   1 
ATOM 155  C CA  . ASN A 1 22  ? 257.092 293.114 400.337 1.00 77.91  ? 22  ASN A CA  1 
ATOM 156  C C   . ASN A 1 22  ? 258.044 293.512 399.217 1.00 77.91  ? 22  ASN A C   1 
ATOM 157  O O   . ASN A 1 22  ? 257.649 293.576 398.050 1.00 77.91  ? 22  ASN A O   1 
ATOM 158  C CB  . ASN A 1 22  ? 257.073 291.589 400.462 1.00 77.91  ? 22  ASN A CB  1 
ATOM 159  C CG  . ASN A 1 22  ? 256.501 291.120 401.781 1.00 77.91  ? 22  ASN A CG  1 
ATOM 160  O OD1 . ASN A 1 22  ? 255.591 290.293 401.817 1.00 77.91  ? 22  ASN A OD1 1 
ATOM 161  N ND2 . ASN A 1 22  ? 257.031 291.650 402.876 1.00 77.91  ? 22  ASN A ND2 1 
ATOM 162  N N   . PRO A 1 23  ? 259.301 293.791 399.547 1.00 73.90  ? 23  PRO A N   1 
ATOM 163  C CA  . PRO A 1 23  ? 260.270 294.146 398.507 1.00 73.90  ? 23  PRO A CA  1 
ATOM 164  C C   . PRO A 1 23  ? 260.535 292.982 397.569 1.00 73.90  ? 23  PRO A C   1 
ATOM 165  O O   . PRO A 1 23  ? 260.427 291.812 397.942 1.00 73.90  ? 23  PRO A O   1 
ATOM 166  C CB  . PRO A 1 23  ? 261.527 294.517 399.303 1.00 73.90  ? 23  PRO A CB  1 
ATOM 167  C CG  . PRO A 1 23  ? 261.354 293.842 400.621 1.00 73.90  ? 23  PRO A CG  1 
ATOM 168  C CD  . PRO A 1 23  ? 259.885 293.853 400.895 1.00 73.90  ? 23  PRO A CD  1 
ATOM 169  N N   . ARG A 1 24  ? 260.879 293.320 396.326 1.00 70.06  ? 24  ARG A N   1 
ATOM 170  C CA  . ARG A 1 24  ? 261.154 292.314 395.310 1.00 70.06  ? 24  ARG A CA  1 
ATOM 171  C C   . ARG A 1 24  ? 262.382 292.676 394.486 1.00 70.06  ? 24  ARG A C   1 
ATOM 172  O O   . ARG A 1 24  ? 262.456 292.347 393.298 1.00 70.06  ? 24  ARG A O   1 
ATOM 173  C CB  . ARG A 1 24  ? 259.949 292.119 394.391 1.00 70.06  ? 24  ARG A CB  1 
ATOM 174  C CG  . ARG A 1 24  ? 258.810 291.348 395.028 1.00 70.06  ? 24  ARG A CG  1 
ATOM 175  C CD  . ARG A 1 24  ? 259.088 289.859 395.018 1.00 70.06  ? 24  ARG A CD  1 
ATOM 176  N NE  . ARG A 1 24  ? 259.165 289.337 393.660 1.00 70.06  ? 24  ARG A NE  1 
ATOM 177  C CZ  . ARG A 1 24  ? 258.126 288.881 392.975 1.00 70.06  ? 24  ARG A CZ  1 
ATOM 178  N NH1 . ARG A 1 24  ? 256.911 288.859 393.497 1.00 70.06  ? 24  ARG A NH1 1 
ATOM 179  N NH2 . ARG A 1 24  ? 258.310 288.436 391.736 1.00 70.06  ? 24  ARG A NH2 1 
ATOM 180  N N   . GLY A 1 25  ? 263.345 293.360 395.094 1.00 76.15  ? 25  GLY A N   1 
ATOM 181  C CA  . GLY A 1 25  ? 264.581 293.693 394.412 1.00 76.15  ? 25  GLY A CA  1 
ATOM 182  C C   . GLY A 1 25  ? 264.371 294.730 393.324 1.00 76.15  ? 25  GLY A C   1 
ATOM 183  O O   . GLY A 1 25  ? 263.283 295.263 393.120 1.00 76.15  ? 25  GLY A O   1 
ATOM 184  N N   . VAL A 1 26  ? 265.454 295.010 392.606 1.00 67.71  ? 26  VAL A N   1 
ATOM 185  C CA  . VAL A 1 26  ? 265.447 295.974 391.515 1.00 67.71  ? 26  VAL A CA  1 
ATOM 186  C C   . VAL A 1 26  ? 265.933 295.280 390.250 1.00 67.71  ? 26  VAL A C   1 
ATOM 187  O O   . VAL A 1 26  ? 266.918 294.534 390.280 1.00 67.71  ? 26  VAL A O   1 
ATOM 188  C CB  . VAL A 1 26  ? 266.298 297.216 391.845 1.00 67.71  ? 26  VAL A CB  1 
ATOM 189  C CG1 . VAL A 1 26  ? 267.764 296.860 391.993 1.00 67.71  ? 26  VAL A CG1 1 
ATOM 190  C CG2 . VAL A 1 26  ? 266.116 298.278 390.775 1.00 67.71  ? 26  VAL A CG2 1 
ATOM 191  N N   . ASN A 1 27  ? 265.220 295.494 389.158 1.00 67.13  ? 27  ASN A N   1 
ATOM 192  C CA  . ASN A 1 27  ? 265.596 294.903 387.883 1.00 67.13  ? 27  ASN A CA  1 
ATOM 193  C C   . ASN A 1 27  ? 266.828 295.612 387.340 1.00 67.13  ? 27  ASN A C   1 
ATOM 194  O O   . ASN A 1 27  ? 266.784 296.829 387.123 1.00 67.13  ? 27  ASN A O   1 
ATOM 195  C CB  . ASN A 1 27  ? 264.434 295.011 386.901 1.00 67.13  ? 27  ASN A CB  1 
ATOM 196  C CG  . ASN A 1 27  ? 264.661 294.213 385.634 1.00 67.13  ? 27  ASN A CG  1 
ATOM 197  O OD1 . ASN A 1 27  ? 265.700 293.580 385.459 1.00 67.13  ? 27  ASN A OD1 1 
ATOM 198  N ND2 . ASN A 1 27  ? 263.682 294.242 384.737 1.00 67.13  ? 27  ASN A ND2 1 
ATOM 199  N N   . PRO A 1 28  ? 267.938 294.910 387.106 1.00 63.69  ? 28  PRO A N   1 
ATOM 200  C CA  . PRO A 1 28  ? 269.141 295.568 386.587 1.00 63.69  ? 28  PRO A CA  1 
ATOM 201  C C   . PRO A 1 28  ? 269.092 295.887 385.103 1.00 63.69  ? 28  PRO A C   1 
ATOM 202  O O   . PRO A 1 28  ? 269.998 296.567 384.608 1.00 63.69  ? 28  PRO A O   1 
ATOM 203  C CB  . PRO A 1 28  ? 270.241 294.543 386.887 1.00 63.69  ? 28  PRO A CB  1 
ATOM 204  C CG  . PRO A 1 28  ? 269.542 293.240 386.849 1.00 63.69  ? 28  PRO A CG  1 
ATOM 205  C CD  . PRO A 1 28  ? 268.173 293.489 387.412 1.00 63.69  ? 28  PRO A CD  1 
ATOM 206  N N   . THR A 1 29  ? 268.078 295.418 384.375 1.00 66.46  ? 29  THR A N   1 
ATOM 207  C CA  . THR A 1 29  ? 267.994 295.730 382.952 1.00 66.46  ? 29  THR A CA  1 
ATOM 208  C C   . THR A 1 29  ? 267.757 297.217 382.723 1.00 66.46  ? 29  THR A C   1 
ATOM 209  O O   . THR A 1 29  ? 268.352 297.813 381.818 1.00 66.46  ? 29  THR A O   1 
ATOM 210  C CB  . THR A 1 29  ? 266.887 294.909 382.295 1.00 66.46  ? 29  THR A CB  1 
ATOM 211  O OG1 . THR A 1 29  ? 265.635 295.202 382.927 1.00 66.46  ? 29  THR A OG1 1 
ATOM 212  C CG2 . THR A 1 29  ? 267.179 293.423 382.423 1.00 66.46  ? 29  THR A CG2 1 
ATOM 213  N N   . ASN A 1 30  ? 266.893 297.834 383.530 1.00 63.55  ? 30  ASN A N   1 
ATOM 214  C CA  . ASN A 1 30  ? 266.569 299.244 383.374 1.00 63.55  ? 30  ASN A CA  1 
ATOM 215  C C   . ASN A 1 30  ? 266.604 300.039 384.670 1.00 63.55  ? 30  ASN A C   1 
ATOM 216  O O   . ASN A 1 30  ? 266.460 301.265 384.619 1.00 63.55  ? 30  ASN A O   1 
ATOM 217  C CB  . ASN A 1 30  ? 265.183 299.409 382.733 1.00 63.55  ? 30  ASN A CB  1 
ATOM 218  C CG  . ASN A 1 30  ? 264.085 298.741 383.535 1.00 63.55  ? 30  ASN A CG  1 
ATOM 219  O OD1 . ASN A 1 30  ? 264.318 298.228 384.628 1.00 63.55  ? 30  ASN A OD1 1 
ATOM 220  N ND2 . ASN A 1 30  ? 262.874 298.744 382.991 1.00 63.55  ? 30  ASN A ND2 1 
ATOM 221  N N   . GLY A 1 31  ? 266.782 299.396 385.818 1.00 63.75  ? 31  GLY A N   1 
ATOM 222  C CA  . GLY A 1 31  ? 266.850 300.112 387.075 1.00 63.75  ? 31  GLY A CA  1 
ATOM 223  C C   . GLY A 1 31  ? 265.491 300.524 387.593 1.00 63.75  ? 31  GLY A C   1 
ATOM 224  O O   . GLY A 1 31  ? 265.259 301.702 387.877 1.00 63.75  ? 31  GLY A O   1 
ATOM 225  N N   . VAL A 1 32  ? 264.583 299.561 387.721 1.00 62.20  ? 32  VAL A N   1 
ATOM 226  C CA  . VAL A 1 32  ? 263.234 299.806 388.215 1.00 62.20  ? 32  VAL A CA  1 
ATOM 227  C C   . VAL A 1 32  ? 262.983 298.867 389.383 1.00 62.20  ? 32  VAL A C   1 
ATOM 228  O O   . VAL A 1 32  ? 263.060 297.643 389.226 1.00 62.20  ? 32  VAL A O   1 
ATOM 229  C CB  . VAL A 1 32  ? 262.175 299.598 387.122 1.00 62.20  ? 32  VAL A CB  1 
ATOM 230  C CG1 . VAL A 1 32  ? 260.781 299.733 387.706 1.00 62.20  ? 32  VAL A CG1 1 
ATOM 231  C CG2 . VAL A 1 32  ? 262.382 300.584 385.989 1.00 62.20  ? 32  VAL A CG2 1 
ATOM 232  N N   . ALA A 1 33  ? 262.677 299.432 390.547 1.00 62.29  ? 33  ALA A N   1 
ATOM 233  C CA  . ALA A 1 33  ? 262.371 298.613 391.707 1.00 62.29  ? 33  ALA A CA  1 
ATOM 234  C C   . ALA A 1 33  ? 261.000 297.962 391.544 1.00 62.29  ? 33  ALA A C   1 
ATOM 235  O O   . ALA A 1 33  ? 260.321 298.118 390.527 1.00 62.29  ? 33  ALA A O   1 
ATOM 236  C CB  . ALA A 1 33  ? 262.418 299.449 392.984 1.00 62.29  ? 33  ALA A CB  1 
ATOM 237  N N   . SER A 1 34  ? 260.592 297.213 392.566 1.00 71.06  ? 34  SER A N   1 
ATOM 238  C CA  . SER A 1 34  ? 259.304 296.539 392.527 1.00 71.06  ? 34  SER A CA  1 
ATOM 239  C C   . SER A 1 34  ? 258.836 296.253 393.944 1.00 71.06  ? 34  SER A C   1 
ATOM 240  O O   . SER A 1 34  ? 259.622 296.253 394.893 1.00 71.06  ? 34  SER A O   1 
ATOM 241  C CB  . SER A 1 34  ? 259.371 295.237 391.720 1.00 71.06  ? 34  SER A CB  1 
ATOM 242  O OG  . SER A 1 34  ? 259.760 295.481 390.380 1.00 71.06  ? 34  SER A OG  1 
ATOM 243  N N   . LEU A 1 35  ? 257.535 296.010 394.069 1.00 72.88  ? 35  LEU A N   1 
ATOM 244  C CA  . LEU A 1 35  ? 256.923 295.576 395.315 1.00 72.88  ? 35  LEU A CA  1 
ATOM 245  C C   . LEU A 1 35  ? 255.848 294.551 394.988 1.00 72.88  ? 35  LEU A C   1 
ATOM 246  O O   . LEU A 1 35  ? 255.476 294.363 393.827 1.00 72.88  ? 35  LEU A O   1 
ATOM 247  C CB  . LEU A 1 35  ? 256.327 296.750 396.102 1.00 72.88  ? 35  LEU A CB  1 
ATOM 248  C CG  . LEU A 1 35  ? 257.296 297.836 396.569 1.00 72.88  ? 35  LEU A CG  1 
ATOM 249  C CD1 . LEU A 1 35  ? 256.543 299.013 397.157 1.00 72.88  ? 35  LEU A CD1 1 
ATOM 250  C CD2 . LEU A 1 35  ? 258.262 297.267 397.587 1.00 72.88  ? 35  LEU A CD2 1 
ATOM 251  N N   . SER A 1 36  ? 255.354 293.876 396.022 1.00 81.76  ? 36  SER A N   1 
ATOM 252  C CA  . SER A 1 36  ? 254.388 292.808 395.818 1.00 81.76  ? 36  SER A CA  1 
ATOM 253  C C   . SER A 1 36  ? 253.614 292.559 397.102 1.00 81.76  ? 36  SER A C   1 
ATOM 254  O O   . SER A 1 36  ? 254.050 292.928 398.194 1.00 81.76  ? 36  SER A O   1 
ATOM 255  C CB  . SER A 1 36  ? 255.078 291.522 395.357 1.00 81.76  ? 36  SER A CB  1 
ATOM 256  O OG  . SER A 1 36  ? 254.194 290.422 395.432 1.00 81.76  ? 36  SER A OG  1 
ATOM 257  N N   . GLN A 1 37  ? 252.458 291.917 396.955 1.00 82.95  ? 37  GLN A N   1 
ATOM 258  C CA  . GLN A 1 37  ? 251.647 291.552 398.105 1.00 82.95  ? 37  GLN A CA  1 
ATOM 259  C C   . GLN A 1 37  ? 252.296 290.397 398.863 1.00 82.95  ? 37  GLN A C   1 
ATOM 260  O O   . GLN A 1 37  ? 253.145 289.673 398.336 1.00 82.95  ? 37  GLN A O   1 
ATOM 261  C CB  . GLN A 1 37  ? 250.232 291.178 397.665 1.00 82.95  ? 37  GLN A CB  1 
ATOM 262  C CG  . GLN A 1 37  ? 249.187 291.315 398.756 1.00 82.95  ? 37  GLN A CG  1 
ATOM 263  C CD  . GLN A 1 37  ? 247.799 290.943 398.281 1.00 82.95  ? 37  GLN A CD  1 
ATOM 264  O OE1 . GLN A 1 37  ? 247.605 290.572 397.124 1.00 82.95  ? 37  GLN A OE1 1 
ATOM 265  N NE2 . GLN A 1 37  ? 246.823 291.039 399.175 1.00 82.95  ? 37  GLN A NE2 1 
ATOM 266  N N   . ALA A 1 38  ? 251.889 290.236 400.124 1.00 82.04  ? 38  ALA A N   1 
ATOM 267  C CA  . ALA A 1 38  ? 252.561 289.289 401.010 1.00 82.04  ? 38  ALA A CA  1 
ATOM 268  C C   . ALA A 1 38  ? 252.447 287.859 400.495 1.00 82.04  ? 38  ALA A C   1 
ATOM 269  O O   . ALA A 1 38  ? 253.446 287.247 400.100 1.00 82.04  ? 38  ALA A O   1 
ATOM 270  C CB  . ALA A 1 38  ? 251.985 289.400 402.423 1.00 82.04  ? 38  ALA A CB  1 
ATOM 271  N N   . GLY A 1 39  ? 251.237 287.308 400.488 1.00 83.37  ? 39  GLY A N   1 
ATOM 272  C CA  . GLY A 1 39  ? 251.041 285.943 400.040 1.00 83.37  ? 39  GLY A CA  1 
ATOM 273  C C   . GLY A 1 39  ? 250.156 285.823 398.819 1.00 83.37  ? 39  GLY A C   1 
ATOM 274  O O   . GLY A 1 39  ? 248.946 286.052 398.908 1.00 83.37  ? 39  GLY A O   1 
ATOM 275  N N   . ALA A 1 40  ? 250.733 285.457 397.677 1.00 80.18  ? 40  ALA A N   1 
ATOM 276  C CA  . ALA A 1 40  ? 249.947 285.308 396.462 1.00 80.18  ? 40  ALA A CA  1 
ATOM 277  C C   . ALA A 1 40  ? 250.730 284.502 395.438 1.00 80.18  ? 40  ALA A C   1 
ATOM 278  O O   . ALA A 1 40  ? 251.962 284.472 395.471 1.00 80.18  ? 40  ALA A O   1 
ATOM 279  C CB  . ALA A 1 40  ? 249.562 286.669 395.875 1.00 80.18  ? 40  ALA A CB  1 
ATOM 280  N N   . VAL A 1 41  ? 250.002 283.845 394.547 1.00 82.63  ? 41  VAL A N   1 
ATOM 281  C CA  . VAL A 1 41  ? 250.616 283.174 393.396 1.00 82.63  ? 41  VAL A CA  1 
ATOM 282  C C   . VAL A 1 41  ? 251.266 284.226 392.505 1.00 82.63  ? 41  VAL A C   1 
ATOM 283  O O   . VAL A 1 41  ? 250.669 285.295 392.289 1.00 82.63  ? 41  VAL A O   1 
ATOM 284  C CB  . VAL A 1 41  ? 249.555 282.373 392.634 1.00 82.63  ? 41  VAL A CB  1 
ATOM 285  C CG1 . VAL A 1 41  ? 250.121 281.733 391.372 1.00 82.63  ? 41  VAL A CG1 1 
ATOM 286  C CG2 . VAL A 1 41  ? 248.943 281.317 393.543 1.00 82.63  ? 41  VAL A CG2 1 
ATOM 287  N N   . PRO A 1 42  ? 252.462 283.977 391.947 1.00 78.95  ? 42  PRO A N   1 
ATOM 288  C CA  . PRO A 1 42  ? 253.202 285.051 391.265 1.00 78.95  ? 42  PRO A CA  1 
ATOM 289  C C   . PRO A 1 42  ? 252.512 285.645 390.046 1.00 78.95  ? 42  PRO A C   1 
ATOM 290  O O   . PRO A 1 42  ? 253.095 286.490 389.361 1.00 78.95  ? 42  PRO A O   1 
ATOM 291  C CB  . PRO A 1 42  ? 254.521 284.370 390.874 1.00 78.95  ? 42  PRO A CB  1 
ATOM 292  C CG  . PRO A 1 42  ? 254.667 283.263 391.847 1.00 78.95  ? 42  PRO A CG  1 
ATOM 293  C CD  . PRO A 1 42  ? 253.281 282.764 392.093 1.00 78.95  ? 42  PRO A CD  1 
ATOM 294  N N   . ALA A 1 43  ? 251.283 285.226 389.759 1.00 78.58  ? 43  ALA A N   1 
ATOM 295  C CA  . ALA A 1 43  ? 250.508 285.834 388.688 1.00 78.58  ? 43  ALA A CA  1 
ATOM 296  C C   . ALA A 1 43  ? 249.350 286.689 389.185 1.00 78.58  ? 43  ALA A C   1 
ATOM 297  O O   . ALA A 1 43  ? 248.595 287.209 388.358 1.00 78.58  ? 43  ALA A O   1 
ATOM 298  C CB  . ALA A 1 43  ? 249.967 284.755 387.744 1.00 78.58  ? 43  ALA A CB  1 
ATOM 299  N N   . LEU A 1 44  ? 249.188 286.858 390.502 1.00 84.17  ? 44  LEU A N   1 
ATOM 300  C CA  . LEU A 1 44  ? 248.016 287.538 391.045 1.00 84.17  ? 44  LEU A CA  1 
ATOM 301  C C   . LEU A 1 44  ? 248.366 288.523 392.158 1.00 84.17  ? 44  LEU A C   1 
ATOM 302  O O   . LEU A 1 44  ? 247.531 288.797 393.023 1.00 84.17  ? 44  LEU A O   1 
ATOM 303  C CB  . LEU A 1 44  ? 246.992 286.527 391.560 1.00 84.17  ? 44  LEU A CB  1 
ATOM 304  C CG  . LEU A 1 44  ? 246.525 285.409 390.632 1.00 84.17  ? 44  LEU A CG  1 
ATOM 305  C CD1 . LEU A 1 44  ? 245.544 284.511 391.358 1.00 84.17  ? 44  LEU A CD1 1 
ATOM 306  C CD2 . LEU A 1 44  ? 245.886 285.989 389.390 1.00 84.17  ? 44  LEU A CD2 1 
ATOM 307  N N   . GLU A 1 45  ? 249.577 289.072 392.165 1.00 85.94  ? 45  GLU A N   1 
ATOM 308  C CA  . GLU A 1 45  ? 249.914 290.077 393.166 1.00 85.94  ? 45  GLU A CA  1 
ATOM 309  C C   . GLU A 1 45  ? 249.486 291.464 392.700 1.00 85.94  ? 45  GLU A C   1 
ATOM 310  O O   . GLU A 1 45  ? 248.758 291.631 391.719 1.00 85.94  ? 45  GLU A O   1 
ATOM 311  C CB  . GLU A 1 45  ? 251.401 290.061 393.502 1.00 85.94  ? 45  GLU A CB  1 
ATOM 312  C CG  . GLU A 1 45  ? 251.884 288.827 394.217 1.00 85.94  ? 45  GLU A CG  1 
ATOM 313  C CD  . GLU A 1 45  ? 252.175 287.687 393.291 1.00 85.94  ? 45  GLU A CD  1 
ATOM 314  O OE1 . GLU A 1 45  ? 252.058 287.873 392.061 1.00 85.94  ? 45  GLU A OE1 1 
ATOM 315  O OE2 . GLU A 1 45  ? 252.538 286.608 393.801 1.00 85.94  ? 45  GLU A OE2 1 
ATOM 316  N N   . LYS A 1 46  ? 249.949 292.482 393.424 1.00 76.83  ? 46  LYS A N   1 
ATOM 317  C CA  . LYS A 1 46  ? 249.612 293.881 393.176 1.00 76.83  ? 46  LYS A CA  1 
ATOM 318  C C   . LYS A 1 46  ? 250.941 294.599 392.964 1.00 76.83  ? 46  LYS A C   1 
ATOM 319  O O   . LYS A 1 46  ? 251.515 295.148 393.907 1.00 76.83  ? 46  LYS A O   1 
ATOM 320  C CB  . LYS A 1 46  ? 248.833 294.455 394.350 1.00 76.83  ? 46  LYS A CB  1 
ATOM 321  C CG  . LYS A 1 46  ? 247.827 293.477 394.934 1.00 76.83  ? 46  LYS A CG  1 
ATOM 322  C CD  . LYS A 1 46  ? 246.578 293.368 394.088 1.00 76.83  ? 46  LYS A CD  1 
ATOM 323  C CE  . LYS A 1 46  ? 245.655 294.540 394.340 1.00 76.83  ? 46  LYS A CE  1 
ATOM 324  N NZ  . LYS A 1 46  ? 245.163 294.532 395.743 1.00 76.83  ? 46  LYS A NZ  1 
ATOM 325  N N   . ARG A 1 47  ? 251.430 294.592 391.728 1.00 71.26  ? 47  ARG A N   1 
ATOM 326  C CA  . ARG A 1 47  ? 252.763 295.105 391.449 1.00 71.26  ? 47  ARG A CA  1 
ATOM 327  C C   . ARG A 1 47  ? 252.818 296.614 391.648 1.00 71.26  ? 47  ARG A C   1 
ATOM 328  O O   . ARG A 1 47  ? 251.927 297.343 391.205 1.00 71.26  ? 47  ARG A O   1 
ATOM 329  C CB  . ARG A 1 47  ? 253.176 294.745 390.025 1.00 71.26  ? 47  ARG A CB  1 
ATOM 330  C CG  . ARG A 1 47  ? 254.108 293.551 389.938 1.00 71.26  ? 47  ARG A CG  1 
ATOM 331  C CD  . ARG A 1 47  ? 254.372 293.171 388.492 1.00 71.26  ? 47  ARG A CD  1 
ATOM 332  N NE  . ARG A 1 47  ? 253.200 292.574 387.862 1.00 71.26  ? 47  ARG A NE  1 
ATOM 333  C CZ  . ARG A 1 47  ? 252.727 291.366 388.141 1.00 71.26  ? 47  ARG A CZ  1 
ATOM 334  N NH1 . ARG A 1 47  ? 253.321 290.576 389.021 1.00 71.26  ? 47  ARG A NH1 1 
ATOM 335  N NH2 . ARG A 1 47  ? 251.634 290.939 387.517 1.00 71.26  ? 47  ARG A NH2 1 
ATOM 336  N N   . VAL A 1 48  ? 253.867 297.079 392.322 1.00 61.26  ? 48  VAL A N   1 
ATOM 337  C CA  . VAL A 1 48  ? 254.137 298.500 392.506 1.00 61.26  ? 48  VAL A CA  1 
ATOM 338  C C   . VAL A 1 48  ? 255.581 298.746 392.099 1.00 61.26  ? 48  VAL A C   1 
ATOM 339  O O   . VAL A 1 48  ? 256.502 298.201 392.718 1.00 61.26  ? 48  VAL A O   1 
ATOM 340  C CB  . VAL A 1 48  ? 253.904 298.951 393.957 1.00 61.26  ? 48  VAL A CB  1 
ATOM 341  C CG1 . VAL A 1 48  ? 254.319 300.398 394.129 1.00 61.26  ? 48  VAL A CG1 1 
ATOM 342  C CG2 . VAL A 1 48  ? 252.451 298.759 394.345 1.00 61.26  ? 48  VAL A CG2 1 
ATOM 343  N N   . THR A 1 49  ? 255.782 299.564 391.070 1.00 62.85  ? 49  THR A N   1 
ATOM 344  C CA  . THR A 1 49  ? 257.106 299.812 390.518 1.00 62.85  ? 49  THR A CA  1 
ATOM 345  C C   . THR A 1 49  ? 257.453 301.287 390.649 1.00 62.85  ? 49  THR A C   1 
ATOM 346  O O   . THR A 1 49  ? 256.636 302.152 390.320 1.00 62.85  ? 49  THR A O   1 
ATOM 347  C CB  . THR A 1 49  ? 257.181 299.389 389.050 1.00 62.85  ? 49  THR A CB  1 
ATOM 348  O OG1 . THR A 1 49  ? 256.411 300.293 388.252 1.00 62.85  ? 49  THR A OG1 1 
ATOM 349  C CG2 . THR A 1 49  ? 256.635 297.984 388.875 1.00 62.85  ? 49  THR A CG2 1 
ATOM 350  N N   . VAL A 1 50  ? 258.665 301.569 391.129 1.00 56.83  ? 50  VAL A N   1 
ATOM 351  C CA  . VAL A 1 50  ? 259.183 302.925 391.229 1.00 56.83  ? 50  VAL A CA  1 
ATOM 352  C C   . VAL A 1 50  ? 260.559 302.956 390.580 1.00 56.83  ? 50  VAL A C   1 
ATOM 353  O O   . VAL A 1 50  ? 261.246 301.937 390.482 1.00 56.83  ? 50  VAL A O   1 
ATOM 354  C CB  . VAL A 1 50  ? 259.268 303.419 392.688 1.00 56.83  ? 50  VAL A CB  1 
ATOM 355  C CG1 . VAL A 1 50  ? 257.900 303.389 393.335 1.00 56.83  ? 50  VAL A CG1 1 
ATOM 356  C CG2 . VAL A 1 50  ? 260.244 302.573 393.474 1.00 56.83  ? 50  VAL A CG2 1 
ATOM 357  N N   . SER A 1 51  ? 260.959 304.145 390.137 1.00 65.72  ? 51  SER A N   1 
ATOM 358  C CA  . SER A 1 51  ? 262.245 304.310 389.474 1.00 65.72  ? 51  SER A CA  1 
ATOM 359  C C   . SER A 1 51  ? 262.531 305.791 389.294 1.00 65.72  ? 51  SER A C   1 
ATOM 360  O O   . SER A 1 51  ? 261.611 306.607 389.211 1.00 65.72  ? 51  SER A O   1 
ATOM 361  C CB  . SER A 1 51  ? 262.272 303.608 388.111 1.00 65.72  ? 51  SER A CB  1 
ATOM 362  O OG  . SER A 1 51  ? 261.417 304.259 387.189 1.00 65.72  ? 51  SER A OG  1 
ATOM 363  N N   . VAL A 1 52  ? 263.818 306.123 389.231 1.00 64.44  ? 52  VAL A N   1 
ATOM 364  C CA  . VAL A 1 52  ? 264.271 307.460 388.884 1.00 64.44  ? 52  VAL A CA  1 
ATOM 365  C C   . VAL A 1 52  ? 265.090 307.357 387.605 1.00 64.44  ? 52  VAL A C   1 
ATOM 366  O O   . VAL A 1 52  ? 265.291 306.274 387.057 1.00 64.44  ? 52  VAL A O   1 
ATOM 367  C CB  . VAL A 1 52  ? 265.086 308.119 390.010 1.00 64.44  ? 52  VAL A CB  1 
ATOM 368  C CG1 . VAL A 1 52  ? 264.300 308.106 391.306 1.00 64.44  ? 52  VAL A CG1 1 
ATOM 369  C CG2 . VAL A 1 52  ? 266.412 307.411 390.181 1.00 64.44  ? 52  VAL A CG2 1 
ATOM 370  N N   . SER A 1 53  ? 265.561 308.504 387.126 1.00 79.09  ? 53  SER A N   1 
ATOM 371  C CA  . SER A 1 53  ? 266.322 308.539 385.883 1.00 79.09  ? 53  SER A CA  1 
ATOM 372  C C   . SER A 1 53  ? 267.159 309.806 385.841 1.00 79.09  ? 53  SER A C   1 
ATOM 373  O O   . SER A 1 53  ? 266.622 310.909 385.968 1.00 79.09  ? 53  SER A O   1 
ATOM 374  C CB  . SER A 1 53  ? 265.394 308.468 384.670 1.00 79.09  ? 53  SER A CB  1 
ATOM 375  O OG  . SER A 1 53  ? 264.788 307.191 384.568 1.00 79.09  ? 53  SER A OG  1 
ATOM 376  N N   . GLN A 1 54  ? 268.463 309.643 385.665 1.00 89.15  ? 54  GLN A N   1 
ATOM 377  C CA  . GLN A 1 54  ? 269.368 310.768 385.530 1.00 89.15  ? 54  GLN A CA  1 
ATOM 378  C C   . GLN A 1 54  ? 269.464 311.197 384.068 1.00 89.15  ? 54  GLN A C   1 
ATOM 379  O O   . GLN A 1 54  ? 269.200 310.405 383.161 1.00 89.15  ? 54  GLN A O   1 
ATOM 380  C CB  . GLN A 1 54  ? 270.738 310.391 386.084 1.00 89.15  ? 54  GLN A CB  1 
ATOM 381  C CG  . GLN A 1 54  ? 270.708 310.062 387.568 1.00 89.15  ? 54  GLN A CG  1 
ATOM 382  C CD  . GLN A 1 54  ? 272.082 309.800 388.141 1.00 89.15  ? 54  GLN A CD  1 
ATOM 383  O OE1 . GLN A 1 54  ? 273.079 309.800 387.420 1.00 89.15  ? 54  GLN A OE1 1 
ATOM 384  N NE2 . GLN A 1 54  ? 272.144 309.575 389.447 1.00 89.15  ? 54  GLN A NE2 1 
ATOM 385  N N   . PRO A 1 55  ? 269.831 312.451 383.809 1.00 93.44  ? 55  PRO A N   1 
ATOM 386  C CA  . PRO A 1 55  ? 269.823 312.950 382.431 1.00 93.44  ? 55  PRO A CA  1 
ATOM 387  C C   . PRO A 1 55  ? 270.899 312.298 381.578 1.00 93.44  ? 55  PRO A C   1 
ATOM 388  O O   . PRO A 1 55  ? 271.882 311.740 382.071 1.00 93.44  ? 55  PRO A O   1 
ATOM 389  C CB  . PRO A 1 55  ? 270.083 314.454 382.591 1.00 93.44  ? 55  PRO A CB  1 
ATOM 390  C CG  . PRO A 1 55  ? 269.824 314.745 384.036 1.00 93.44  ? 55  PRO A CG  1 
ATOM 391  C CD  . PRO A 1 55  ? 270.227 313.505 384.754 1.00 93.44  ? 55  PRO A CD  1 
ATOM 392  N N   . SER A 1 56  ? 270.690 312.381 380.270 1.00 107.64 ? 56  SER A N   1 
ATOM 393  C CA  . SER A 1 56  ? 271.596 311.805 379.282 1.00 107.64 ? 56  SER A CA  1 
ATOM 394  C C   . SER A 1 56  ? 271.686 312.787 378.119 1.00 107.64 ? 56  SER A C   1 
ATOM 395  O O   . SER A 1 56  ? 271.337 313.965 378.248 1.00 107.64 ? 56  SER A O   1 
ATOM 396  C CB  . SER A 1 56  ? 271.120 310.409 378.856 1.00 107.64 ? 56  SER A CB  1 
ATOM 397  O OG  . SER A 1 56  ? 271.884 309.925 377.766 1.00 107.64 ? 56  SER A OG  1 
ATOM 398  N N   . ARG A 1 57  ? 272.177 312.308 376.972 1.00 114.09 ? 57  ARG A N   1 
ATOM 399  C CA  . ARG A 1 57  ? 272.220 313.147 375.778 1.00 114.09 ? 57  ARG A CA  1 
ATOM 400  C C   . ARG A 1 57  ? 270.843 313.695 375.428 1.00 114.09 ? 57  ARG A C   1 
ATOM 401  O O   . ARG A 1 57  ? 270.735 314.783 374.852 1.00 114.09 ? 57  ARG A O   1 
ATOM 402  C CB  . ARG A 1 57  ? 272.788 312.360 374.596 1.00 114.09 ? 57  ARG A CB  1 
ATOM 403  C CG  . ARG A 1 57  ? 274.286 312.109 374.667 1.00 114.09 ? 57  ARG A CG  1 
ATOM 404  C CD  . ARG A 1 57  ? 274.756 311.281 373.481 1.00 114.09 ? 57  ARG A CD  1 
ATOM 405  N NE  . ARG A 1 57  ? 276.196 311.052 373.506 1.00 114.09 ? 57  ARG A NE  1 
ATOM 406  C CZ  . ARG A 1 57  ? 276.783 310.041 374.132 1.00 114.09 ? 57  ARG A CZ  1 
ATOM 407  N NH1 . ARG A 1 57  ? 276.081 309.140 374.800 1.00 114.09 ? 57  ARG A NH1 1 
ATOM 408  N NH2 . ARG A 1 57  ? 278.108 309.930 374.085 1.00 114.09 ? 57  ARG A NH2 1 
ATOM 409  N N   . ASN A 1 58  ? 269.788 312.962 375.762 1.00 113.99 ? 58  ASN A N   1 
ATOM 410  C CA  . ASN A 1 58  ? 268.416 313.422 375.623 1.00 113.99 ? 58  ASN A CA  1 
ATOM 411  C C   . ASN A 1 58  ? 267.804 313.595 377.010 1.00 113.99 ? 58  ASN A C   1 
ATOM 412  O O   . ASN A 1 58  ? 268.443 313.311 378.028 1.00 113.99 ? 58  ASN A O   1 
ATOM 413  C CB  . ASN A 1 58  ? 267.607 312.442 374.772 1.00 113.99 ? 58  ASN A CB  1 
ATOM 414  C CG  . ASN A 1 58  ? 268.026 312.456 373.316 1.00 113.99 ? 58  ASN A CG  1 
ATOM 415  O OD1 . ASN A 1 58  ? 268.270 313.515 372.738 1.00 113.99 ? 58  ASN A OD1 1 
ATOM 416  N ND2 . ASN A 1 58  ? 268.114 311.276 372.715 1.00 113.99 ? 58  ASN A ND2 1 
ATOM 417  N N   . ARG A 1 59  ? 266.556 314.075 377.035 1.00 103.07 ? 59  ARG A N   1 
ATOM 418  C CA  . ARG A 1 59  ? 265.771 314.266 378.256 1.00 103.07 ? 59  ARG A CA  1 
ATOM 419  C C   . ARG A 1 59  ? 266.593 314.901 379.377 1.00 103.07 ? 59  ARG A C   1 
ATOM 420  O O   . ARG A 1 59  ? 266.818 314.294 380.429 1.00 103.07 ? 59  ARG A O   1 
ATOM 421  C CB  . ARG A 1 59  ? 265.116 312.941 378.692 1.00 103.07 ? 59  ARG A CB  1 
ATOM 422  C CG  . ARG A 1 59  ? 266.037 311.798 379.110 1.00 103.07 ? 59  ARG A CG  1 
ATOM 423  C CD  . ARG A 1 59  ? 265.251 310.577 379.540 1.00 103.07 ? 59  ARG A CD  1 
ATOM 424  N NE  . ARG A 1 59  ? 266.135 309.464 379.860 1.00 103.07 ? 59  ARG A NE  1 
ATOM 425  C CZ  . ARG A 1 59  ? 266.673 309.257 381.054 1.00 103.07 ? 59  ARG A CZ  1 
ATOM 426  N NH1 . ARG A 1 59  ? 266.452 310.083 382.063 1.00 103.07 ? 59  ARG A NH1 1 
ATOM 427  N NH2 . ARG A 1 59  ? 267.459 308.201 381.237 1.00 103.07 ? 59  ARG A NH2 1 
ATOM 428  N N   . LYS A 1 60  ? 267.029 316.144 379.158 1.00 98.06  ? 60  LYS A N   1 
ATOM 429  C CA  . LYS A 1 60  ? 267.950 316.803 380.078 1.00 98.06  ? 60  LYS A CA  1 
ATOM 430  C C   . LYS A 1 60  ? 267.377 316.964 381.480 1.00 98.06  ? 60  LYS A C   1 
ATOM 431  O O   . LYS A 1 60  ? 268.143 317.174 382.427 1.00 98.06  ? 60  LYS A O   1 
ATOM 432  C CB  . LYS A 1 60  ? 268.344 318.170 379.518 1.00 98.06  ? 60  LYS A CB  1 
ATOM 433  C CG  . LYS A 1 60  ? 269.112 318.097 378.212 1.00 98.06  ? 60  LYS A CG  1 
ATOM 434  C CD  . LYS A 1 60  ? 269.532 319.476 377.739 1.00 98.06  ? 60  LYS A CD  1 
ATOM 435  C CE  . LYS A 1 60  ? 268.331 320.279 377.271 1.00 98.06  ? 60  LYS A CE  1 
ATOM 436  N NZ  . LYS A 1 60  ? 267.715 319.687 376.052 1.00 98.06  ? 60  LYS A NZ  1 
ATOM 437  N N   . ASN A 1 61  ? 266.062 316.877 381.637 1.00 89.01  ? 61  ASN A N   1 
ATOM 438  C CA  . ASN A 1 61  ? 265.432 317.011 382.941 1.00 89.01  ? 61  ASN A CA  1 
ATOM 439  C C   . ASN A 1 61  ? 265.292 315.653 383.619 1.00 89.01  ? 61  ASN A C   1 
ATOM 440  O O   . ASN A 1 61  ? 265.223 314.612 382.961 1.00 89.01  ? 61  ASN A O   1 
ATOM 441  C CB  . ASN A 1 61  ? 264.059 317.666 382.804 1.00 89.01  ? 61  ASN A CB  1 
ATOM 442  C CG  . ASN A 1 61  ? 263.212 317.014 381.733 1.00 89.01  ? 61  ASN A CG  1 
ATOM 443  O OD1 . ASN A 1 61  ? 263.673 316.125 381.018 1.00 89.01  ? 61  ASN A OD1 1 
ATOM 444  N ND2 . ASN A 1 61  ? 261.964 317.454 381.614 1.00 89.01  ? 61  ASN A ND2 1 
ATOM 445  N N   . TYR A 1 62  ? 265.251 315.678 384.949 1.00 75.25  ? 62  TYR A N   1 
ATOM 446  C CA  . TYR A 1 62  ? 265.042 314.469 385.730 1.00 75.25  ? 62  TYR A CA  1 
ATOM 447  C C   . TYR A 1 62  ? 263.687 313.848 385.404 1.00 75.25  ? 62  TYR A C   1 
ATOM 448  O O   . TYR A 1 62  ? 262.825 314.463 384.773 1.00 75.25  ? 62  TYR A O   1 
ATOM 449  C CB  . TYR A 1 62  ? 265.128 314.780 387.222 1.00 75.25  ? 62  TYR A CB  1 
ATOM 450  C CG  . TYR A 1 62  ? 266.535 314.809 387.769 1.00 75.25  ? 62  TYR A CG  1 
ATOM 451  C CD1 . TYR A 1 62  ? 267.515 313.976 387.259 1.00 75.25  ? 62  TYR A CD1 1 
ATOM 452  C CD2 . TYR A 1 62  ? 266.888 315.691 388.779 1.00 75.25  ? 62  TYR A CD2 1 
ATOM 453  C CE1 . TYR A 1 62  ? 268.801 314.001 387.759 1.00 75.25  ? 62  TYR A CE1 1 
ATOM 454  C CE2 . TYR A 1 62  ? 268.170 315.724 389.283 1.00 75.25  ? 62  TYR A CE2 1 
ATOM 455  C CZ  . TYR A 1 62  ? 269.124 314.879 388.767 1.00 75.25  ? 62  TYR A CZ  1 
ATOM 456  O OH  . TYR A 1 62  ? 270.405 314.910 389.262 1.00 75.25  ? 62  TYR A OH  1 
ATOM 457  N N   . LYS A 1 63  ? 263.503 312.606 385.847 1.00 71.02  ? 63  LYS A N   1 
ATOM 458  C CA  . LYS A 1 63  ? 262.274 311.873 385.574 1.00 71.02  ? 63  LYS A CA  1 
ATOM 459  C C   . LYS A 1 63  ? 262.062 310.803 386.631 1.00 71.02  ? 63  LYS A C   1 
ATOM 460  O O   . LYS A 1 63  ? 262.988 310.055 386.955 1.00 71.02  ? 63  LYS A O   1 
ATOM 461  C CB  . LYS A 1 63  ? 262.315 311.230 384.186 1.00 71.02  ? 63  LYS A CB  1 
ATOM 462  C CG  . LYS A 1 63  ? 261.015 310.569 383.780 1.00 71.02  ? 63  LYS A CG  1 
ATOM 463  C CD  . LYS A 1 63  ? 261.119 309.959 382.396 1.00 71.02  ? 63  LYS A CD  1 
ATOM 464  C CE  . LYS A 1 63  ? 261.176 311.035 381.329 1.00 71.02  ? 63  LYS A CE  1 
ATOM 465  N NZ  . LYS A 1 63  ? 259.896 311.788 381.235 1.00 71.02  ? 63  LYS A NZ  1 
ATOM 466  N N   . VAL A 1 64  ? 260.844 310.731 387.159 1.00 63.94  ? 64  VAL A N   1 
ATOM 467  C CA  . VAL A 1 64  ? 260.435 309.681 388.084 1.00 63.94  ? 64  VAL A CA  1 
ATOM 468  C C   . VAL A 1 64  ? 259.173 309.037 387.534 1.00 63.94  ? 64  VAL A C   1 
ATOM 469  O O   . VAL A 1 64  ? 258.223 309.738 387.171 1.00 63.94  ? 64  VAL A O   1 
ATOM 470  C CB  . VAL A 1 64  ? 260.189 310.224 389.501 1.00 63.94  ? 64  VAL A CB  1 
ATOM 471  C CG1 . VAL A 1 64  ? 259.679 309.113 390.396 1.00 63.94  ? 64  VAL A CG1 1 
ATOM 472  C CG2 . VAL A 1 64  ? 261.458 310.825 390.066 1.00 63.94  ? 64  VAL A CG2 1 
ATOM 473  N N   . GLN A 1 65  ? 259.161 307.709 387.477 1.00 65.76  ? 65  GLN A N   1 
ATOM 474  C CA  . GLN A 1 65  ? 258.043 306.963 386.920 1.00 65.76  ? 65  GLN A CA  1 
ATOM 475  C C   . GLN A 1 65  ? 257.541 305.966 387.950 1.00 65.76  ? 65  GLN A C   1 
ATOM 476  O O   . GLN A 1 65  ? 258.338 305.242 388.553 1.00 65.76  ? 65  GLN A O   1 
ATOM 477  C CB  . GLN A 1 65  ? 258.456 306.242 385.636 1.00 65.76  ? 65  GLN A CB  1 
ATOM 478  C CG  . GLN A 1 65  ? 257.310 305.933 384.699 1.00 65.76  ? 65  GLN A CG  1 
ATOM 479  C CD  . GLN A 1 65  ? 257.785 305.622 383.295 1.00 65.76  ? 65  GLN A CD  1 
ATOM 480  O OE1 . GLN A 1 65  ? 258.814 306.129 382.851 1.00 65.76  ? 65  GLN A OE1 1 
ATOM 481  N NE2 . GLN A 1 65  ? 257.037 304.786 382.588 1.00 65.76  ? 65  GLN A NE2 1 
ATOM 482  N N   . VAL A 1 66  ? 256.227 305.934 388.154 1.00 57.01  ? 66  VAL A N   1 
ATOM 483  C CA  . VAL A 1 66  ? 255.593 305.003 389.079 1.00 57.01  ? 66  VAL A CA  1 
ATOM 484  C C   . VAL A 1 66  ? 254.466 304.297 388.341 1.00 57.01  ? 66  VAL A C   1 
ATOM 485  O O   . VAL A 1 66  ? 253.558 304.953 387.818 1.00 57.01  ? 66  VAL A O   1 
ATOM 486  C CB  . VAL A 1 66  ? 255.052 305.709 390.332 1.00 57.01  ? 66  VAL A CB  1 
ATOM 487  C CG1 . VAL A 1 66  ? 254.264 304.733 391.183 1.00 57.01  ? 66  VAL A CG1 1 
ATOM 488  C CG2 . VAL A 1 66  ? 256.188 306.314 391.130 1.00 57.01  ? 66  VAL A CG2 1 
ATOM 489  N N   . LYS A 1 67  ? 254.520 302.969 388.302 1.00 61.90  ? 67  LYS A N   1 
ATOM 490  C CA  . LYS A 1 67  ? 253.483 302.152 387.689 1.00 61.90  ? 67  LYS A CA  1 
ATOM 491  C C   . LYS A 1 67  ? 252.969 301.151 388.710 1.00 61.90  ? 67  LYS A C   1 
ATOM 492  O O   . LYS A 1 67  ? 253.758 300.549 389.445 1.00 61.90  ? 67  LYS A O   1 
ATOM 493  C CB  . LYS A 1 67  ? 254.004 301.413 386.454 1.00 61.90  ? 67  LYS A CB  1 
ATOM 494  C CG  . LYS A 1 67  ? 254.320 302.301 385.272 1.00 61.90  ? 67  LYS A CG  1 
ATOM 495  C CD  . LYS A 1 67  ? 254.709 301.464 384.067 1.00 61.90  ? 67  LYS A CD  1 
ATOM 496  C CE  . LYS A 1 67  ? 254.921 302.328 382.839 1.00 61.90  ? 67  LYS A CE  1 
ATOM 497  N NZ  . LYS A 1 67  ? 255.328 301.521 381.657 1.00 61.90  ? 67  LYS A NZ  1 
ATOM 498  N N   . ILE A 1 68  ? 251.652 300.979 388.755 1.00 61.61  ? 68  ILE A N   1 
ATOM 499  C CA  . ILE A 1 68  ? 251.017 300.010 389.635 1.00 61.61  ? 68  ILE A CA  1 
ATOM 500  C C   . ILE A 1 68  ? 249.992 299.225 388.832 1.00 61.61  ? 68  ILE A C   1 
ATOM 501  O O   . ILE A 1 68  ? 249.368 299.748 387.904 1.00 61.61  ? 68  ILE A O   1 
ATOM 502  C CB  . ILE A 1 68  ? 250.360 300.681 390.858 1.00 61.61  ? 68  ILE A CB  1 
ATOM 503  C CG1 . ILE A 1 68  ? 249.279 301.651 390.404 1.00 61.61  ? 68  ILE A CG1 1 
ATOM 504  C CG2 . ILE A 1 68  ? 251.394 301.404 391.695 1.00 61.61  ? 68  ILE A CG2 1 
ATOM 505  C CD1 . ILE A 1 68  ? 248.519 302.271 391.531 1.00 61.61  ? 68  ILE A CD1 1 
ATOM 506  N N   . GLN A 1 69  ? 249.830 297.955 389.188 1.00 73.01  ? 69  GLN A N   1 
ATOM 507  C CA  . GLN A 1 69  ? 248.898 297.067 388.512 1.00 73.01  ? 69  GLN A CA  1 
ATOM 508  C C   . GLN A 1 69  ? 248.033 296.369 389.547 1.00 73.01  ? 69  GLN A C   1 
ATOM 509  O O   . GLN A 1 69  ? 248.527 295.947 390.596 1.00 73.01  ? 69  GLN A O   1 
ATOM 510  C CB  . GLN A 1 69  ? 249.633 296.030 387.666 1.00 73.01  ? 69  GLN A CB  1 
ATOM 511  C CG  . GLN A 1 69  ? 250.418 296.618 386.514 1.00 73.01  ? 69  GLN A CG  1 
ATOM 512  C CD  . GLN A 1 69  ? 250.439 295.710 385.306 1.00 73.01  ? 69  GLN A CD  1 
ATOM 513  O OE1 . GLN A 1 69  ? 250.288 296.162 384.173 1.00 73.01  ? 69  GLN A OE1 1 
ATOM 514  N NE2 . GLN A 1 69  ? 250.618 294.417 385.543 1.00 73.01  ? 69  GLN A NE2 1 
ATOM 515  N N   . ASN A 1 70  ? 246.743 296.248 389.250 1.00 72.37  ? 70  ASN A N   1 
ATOM 516  C CA  . ASN A 1 70  ? 245.783 295.596 390.138 1.00 72.37  ? 70  ASN A CA  1 
ATOM 517  C C   . ASN A 1 70  ? 244.962 294.596 389.339 1.00 72.37  ? 70  ASN A C   1 
ATOM 518  O O   . ASN A 1 70  ? 243.799 294.857 389.004 1.00 72.37  ? 70  ASN A O   1 
ATOM 519  C CB  . ASN A 1 70  ? 244.879 296.619 390.822 1.00 72.37  ? 70  ASN A CB  1 
ATOM 520  C CG  . ASN A 1 70  ? 245.432 297.082 392.146 1.00 72.37  ? 70  ASN A CG  1 
ATOM 521  O OD1 . ASN A 1 70  ? 246.644 297.099 392.351 1.00 72.37  ? 70  ASN A OD1 1 
ATOM 522  N ND2 . ASN A 1 70  ? 244.547 297.449 393.061 1.00 72.37  ? 70  ASN A ND2 1 
ATOM 523  N N   . PRO A 1 71  ? 245.535 293.442 389.009 1.00 73.23  ? 71  PRO A N   1 
ATOM 524  C CA  . PRO A 1 71  ? 244.742 292.400 388.353 1.00 73.23  ? 71  PRO A CA  1 
ATOM 525  C C   . PRO A 1 71  ? 243.696 291.841 389.303 1.00 73.23  ? 71  PRO A C   1 
ATOM 526  O O   . PRO A 1 71  ? 243.915 291.749 390.512 1.00 73.23  ? 71  PRO A O   1 
ATOM 527  C CB  . PRO A 1 71  ? 245.785 291.344 387.981 1.00 73.23  ? 71  PRO A CB  1 
ATOM 528  C CG  . PRO A 1 71  ? 246.849 291.514 388.998 1.00 73.23  ? 71  PRO A CG  1 
ATOM 529  C CD  . PRO A 1 71  ? 246.901 292.987 389.310 1.00 73.23  ? 71  PRO A CD  1 
ATOM 530  N N   . THR A 1 72  ? 242.549 291.473 388.742 1.00 77.06  ? 72  THR A N   1 
ATOM 531  C CA  . THR A 1 72  ? 241.469 290.850 389.492 1.00 77.06  ? 72  THR A CA  1 
ATOM 532  C C   . THR A 1 72  ? 241.215 289.465 388.921 1.00 77.06  ? 72  THR A C   1 
ATOM 533  O O   . THR A 1 72  ? 241.024 289.314 387.710 1.00 77.06  ? 72  THR A O   1 
ATOM 534  C CB  . THR A 1 72  ? 240.193 291.690 389.435 1.00 77.06  ? 72  THR A CB  1 
ATOM 535  O OG1 . THR A 1 72  ? 239.870 291.980 388.070 1.00 77.06  ? 72  THR A OG1 1 
ATOM 536  C CG2 . THR A 1 72  ? 240.381 292.991 390.196 1.00 77.06  ? 72  THR A CG2 1 
ATOM 537  N N   . ALA A 1 73  ? 241.212 288.462 389.791 1.00 84.79  ? 73  ALA A N   1 
ATOM 538  C CA  . ALA A 1 73  ? 241.103 287.070 389.383 1.00 84.79  ? 73  ALA A CA  1 
ATOM 539  C C   . ALA A 1 73  ? 239.735 286.527 389.762 1.00 84.79  ? 73  ALA A C   1 
ATOM 540  O O   . ALA A 1 73  ? 239.309 286.655 390.915 1.00 84.79  ? 73  ALA A O   1 
ATOM 541  C CB  . ALA A 1 73  ? 242.202 286.224 390.027 1.00 84.79  ? 73  ALA A CB  1 
ATOM 542  N N   . CYS A 1 74  ? 239.055 285.925 388.793 1.00 98.24  ? 74  CYS A N   1 
ATOM 543  C CA  . CYS A 1 74  ? 237.787 285.249 389.017 1.00 98.24  ? 74  CYS A CA  1 
ATOM 544  C C   . CYS A 1 74  ? 237.961 283.765 388.728 1.00 98.24  ? 74  CYS A C   1 
ATOM 545  O O   . CYS A 1 74  ? 238.492 283.389 387.677 1.00 98.24  ? 74  CYS A O   1 
ATOM 546  C CB  . CYS A 1 74  ? 236.680 285.849 388.145 1.00 98.24  ? 74  CYS A CB  1 
ATOM 547  S SG  . CYS A 1 74  ? 236.872 285.605 386.363 1.00 98.24  ? 74  CYS A SG  1 
ATOM 548  N N   . THR A 1 75  ? 237.534 282.927 389.668 1.00 106.88 ? 75  THR A N   1 
ATOM 549  C CA  . THR A 1 75  ? 237.672 281.487 389.505 1.00 106.88 ? 75  THR A CA  1 
ATOM 550  C C   . THR A 1 75  ? 236.650 280.984 388.495 1.00 106.88 ? 75  THR A C   1 
ATOM 551  O O   . THR A 1 75  ? 235.440 281.093 388.720 1.00 106.88 ? 75  THR A O   1 
ATOM 552  C CB  . THR A 1 75  ? 237.492 280.782 390.846 1.00 106.88 ? 75  THR A CB  1 
ATOM 553  O OG1 . THR A 1 75  ? 236.148 280.970 391.307 1.00 106.88 ? 75  THR A OG1 1 
ATOM 554  C CG2 . THR A 1 75  ? 238.456 281.346 391.876 1.00 106.88 ? 75  THR A CG2 1 
ATOM 555  N N   . ALA A 1 76  ? 237.135 280.439 387.382 1.00 112.14 ? 76  ALA A N   1 
ATOM 556  C CA  . ALA A 1 76  ? 236.241 279.916 386.361 1.00 112.14 ? 76  ALA A CA  1 
ATOM 557  C C   . ALA A 1 76  ? 235.433 278.750 386.913 1.00 112.14 ? 76  ALA A C   1 
ATOM 558  O O   . ALA A 1 76  ? 235.940 277.933 387.687 1.00 112.14 ? 76  ALA A O   1 
ATOM 559  C CB  . ALA A 1 76  ? 237.034 279.477 385.130 1.00 112.14 ? 76  ALA A CB  1 
ATOM 560  N N   . ASN A 1 77  ? 234.163 278.684 386.516 1.00 115.50 ? 77  ASN A N   1 
ATOM 561  C CA  . ASN A 1 77  ? 233.257 277.650 387.002 1.00 115.50 ? 77  ASN A CA  1 
ATOM 562  C C   . ASN A 1 77  ? 233.754 276.270 386.595 1.00 115.50 ? 77  ASN A C   1 
ATOM 563  O O   . ASN A 1 77  ? 233.751 275.926 385.408 1.00 115.50 ? 77  ASN A O   1 
ATOM 564  C CB  . ASN A 1 77  ? 231.843 277.891 386.470 1.00 115.50 ? 77  ASN A CB  1 
ATOM 565  C CG  . ASN A 1 77  ? 231.389 279.329 386.650 1.00 115.50 ? 77  ASN A CG  1 
ATOM 566  O OD1 . ASN A 1 77  ? 230.967 279.984 385.695 1.00 115.50 ? 77  ASN A OD1 1 
ATOM 567  N ND2 . ASN A 1 77  ? 231.480 279.830 387.876 1.00 115.50 ? 77  ASN A ND2 1 
ATOM 568  N N   . GLY A 1 78  ? 234.181 275.473 387.570 1.00 114.14 ? 78  GLY A N   1 
ATOM 569  C CA  . GLY A 1 78  ? 234.760 274.179 387.276 1.00 114.14 ? 78  GLY A CA  1 
ATOM 570  C C   . GLY A 1 78  ? 236.111 274.299 386.602 1.00 114.14 ? 78  GLY A C   1 
ATOM 571  O O   . GLY A 1 78  ? 236.266 273.932 385.433 1.00 114.14 ? 78  GLY A O   1 
ATOM 572  N N   . SER A 1 79  ? 237.098 274.818 387.330 1.00 112.55 ? 79  SER A N   1 
ATOM 573  C CA  . SER A 1 79  ? 238.429 275.041 386.787 1.00 112.55 ? 79  SER A CA  1 
ATOM 574  C C   . SER A 1 79  ? 239.472 274.675 387.832 1.00 112.55 ? 79  SER A C   1 
ATOM 575  O O   . SER A 1 79  ? 239.184 274.590 389.028 1.00 112.55 ? 79  SER A O   1 
ATOM 576  C CB  . SER A 1 79  ? 238.617 276.494 386.335 1.00 112.55 ? 79  SER A CB  1 
ATOM 577  O OG  . SER A 1 79  ? 238.513 277.386 387.431 1.00 112.55 ? 79  SER A OG  1 
ATOM 578  N N   . CYS A 1 80  ? 240.699 274.461 387.359 1.00 102.96 ? 80  CYS A N   1 
ATOM 579  C CA  . CYS A 1 80  ? 241.783 274.037 388.238 1.00 102.96 ? 80  CYS A CA  1 
ATOM 580  C C   . CYS A 1 80  ? 242.280 275.188 389.107 1.00 102.96 ? 80  CYS A C   1 
ATOM 581  O O   . CYS A 1 80  ? 242.220 275.122 390.340 1.00 102.96 ? 80  CYS A O   1 
ATOM 582  C CB  . CYS A 1 80  ? 242.931 273.459 387.405 1.00 102.96 ? 80  CYS A CB  1 
ATOM 583  S SG  . CYS A 1 80  ? 242.494 271.989 386.449 1.00 102.96 ? 80  CYS A SG  1 
ATOM 584  N N   . ASP A 1 81  ? 242.772 276.253 388.479 1.00 93.01  ? 81  ASP A N   1 
ATOM 585  C CA  . ASP A 1 81  ? 243.343 277.389 389.179 1.00 93.01  ? 81  ASP A CA  1 
ATOM 586  C C   . ASP A 1 81  ? 242.759 278.700 388.657 1.00 93.01  ? 81  ASP A C   1 
ATOM 587  O O   . ASP A 1 81  ? 242.307 278.768 387.510 1.00 93.01  ? 81  ASP A O   1 
ATOM 588  C CB  . ASP A 1 81  ? 244.872 277.397 389.042 1.00 93.01  ? 81  ASP A CB  1 
ATOM 589  C CG  . ASP A 1 81  ? 245.337 277.447 387.597 1.00 93.01  ? 81  ASP A CG  1 
ATOM 590  O OD1 . ASP A 1 81  ? 246.565 277.481 387.375 1.00 93.01  ? 81  ASP A OD1 1 
ATOM 591  O OD2 . ASP A 1 81  ? 244.489 277.417 386.682 1.00 93.01  ? 81  ASP A OD2 1 
ATOM 592  N N   . PRO A 1 82  ? 242.734 279.747 389.479 1.00 88.28  ? 82  PRO A N   1 
ATOM 593  C CA  . PRO A 1 82  ? 242.143 281.015 389.038 1.00 88.28  ? 82  PRO A CA  1 
ATOM 594  C C   . PRO A 1 82  ? 242.929 281.641 387.897 1.00 88.28  ? 82  PRO A C   1 
ATOM 595  O O   . PRO A 1 82  ? 244.142 281.467 387.763 1.00 88.28  ? 82  PRO A O   1 
ATOM 596  C CB  . PRO A 1 82  ? 242.196 281.890 390.294 1.00 88.28  ? 82  PRO A CB  1 
ATOM 597  C CG  . PRO A 1 82  ? 243.285 281.302 391.117 1.00 88.28  ? 82  PRO A CG  1 
ATOM 598  C CD  . PRO A 1 82  ? 243.225 279.826 390.865 1.00 88.28  ? 82  PRO A CD  1 
ATOM 599  N N   . SER A 1 83  ? 242.205 282.383 387.064 1.00 82.59  ? 83  SER A N   1 
ATOM 600  C CA  . SER A 1 83  ? 242.771 283.048 385.902 1.00 82.59  ? 83  SER A CA  1 
ATOM 601  C C   . SER A 1 83  ? 242.535 284.549 385.996 1.00 82.59  ? 83  SER A C   1 
ATOM 602  O O   . SER A 1 83  ? 241.529 285.003 386.549 1.00 82.59  ? 83  SER A O   1 
ATOM 603  C CB  . SER A 1 83  ? 242.165 282.507 384.603 1.00 82.59  ? 83  SER A CB  1 
ATOM 604  O OG  . SER A 1 83  ? 240.792 282.840 384.507 1.00 82.59  ? 83  SER A OG  1 
ATOM 605  N N   . VAL A 1 84  ? 243.474 285.314 385.451 1.00 77.86  ? 84  VAL A N   1 
ATOM 606  C CA  . VAL A 1 84  ? 243.380 286.769 385.469 1.00 77.86  ? 84  VAL A CA  1 
ATOM 607  C C   . VAL A 1 84  ? 242.388 287.217 384.404 1.00 77.86  ? 84  VAL A C   1 
ATOM 608  O O   . VAL A 1 84  ? 242.423 286.742 383.263 1.00 77.86  ? 84  VAL A O   1 
ATOM 609  C CB  . VAL A 1 84  ? 244.763 287.405 385.259 1.00 77.86  ? 84  VAL A CB  1 
ATOM 610  C CG1 . VAL A 1 84  ? 245.412 286.882 383.988 1.00 77.86  ? 84  VAL A CG1 1 
ATOM 611  C CG2 . VAL A 1 84  ? 244.647 288.916 385.219 1.00 77.86  ? 84  VAL A CG2 1 
ATOM 612  N N   . THR A 1 85  ? 241.483 288.121 384.780 1.00 77.24  ? 85  THR A N   1 
ATOM 613  C CA  . THR A 1 85  ? 240.430 288.576 383.879 1.00 77.24  ? 85  THR A CA  1 
ATOM 614  C C   . THR A 1 85  ? 240.572 290.048 383.521 1.00 77.24  ? 85  THR A C   1 
ATOM 615  O O   . THR A 1 85  ? 240.620 290.385 382.334 1.00 77.24  ? 85  THR A O   1 
ATOM 616  C CB  . THR A 1 85  ? 239.054 288.315 384.503 1.00 77.24  ? 85  THR A CB  1 
ATOM 617  O OG1 . THR A 1 85  ? 238.942 286.932 384.858 1.00 77.24  ? 85  THR A OG1 1 
ATOM 618  C CG2 . THR A 1 85  ? 237.953 288.669 383.520 1.00 77.24  ? 85  THR A CG2 1 
ATOM 619  N N   . ARG A 1 86  ? 240.641 290.937 384.507 1.00 75.36  ? 86  ARG A N   1 
ATOM 620  C CA  . ARG A 1 86  ? 240.648 292.370 384.267 1.00 75.36  ? 86  ARG A CA  1 
ATOM 621  C C   . ARG A 1 86  ? 241.934 292.993 384.794 1.00 75.36  ? 86  ARG A C   1 
ATOM 622  O O   . ARG A 1 86  ? 242.638 292.416 385.626 1.00 75.36  ? 86  ARG A O   1 
ATOM 623  C CB  . ARG A 1 86  ? 239.439 293.047 384.922 1.00 75.36  ? 86  ARG A CB  1 
ATOM 624  C CG  . ARG A 1 86  ? 238.103 292.606 384.357 1.00 75.36  ? 86  ARG A CG  1 
ATOM 625  C CD  . ARG A 1 86  ? 236.973 293.449 384.914 1.00 75.36  ? 86  ARG A CD  1 
ATOM 626  N NE  . ARG A 1 86  ? 236.883 293.341 386.365 1.00 75.36  ? 86  ARG A NE  1 
ATOM 627  C CZ  . ARG A 1 86  ? 236.188 292.410 387.002 1.00 75.36  ? 86  ARG A CZ  1 
ATOM 628  N NH1 . ARG A 1 86  ? 235.499 291.491 386.345 1.00 75.36  ? 86  ARG A NH1 1 
ATOM 629  N NH2 . ARG A 1 86  ? 236.182 292.400 388.331 1.00 75.36  ? 86  ARG A NH2 1 
ATOM 630  N N   . GLN A 1 87  ? 242.228 294.188 384.292 1.00 70.63  ? 87  GLN A N   1 
ATOM 631  C CA  . GLN A 1 87  ? 243.403 294.945 384.690 1.00 70.63  ? 87  GLN A CA  1 
ATOM 632  C C   . GLN A 1 87  ? 242.980 296.345 385.107 1.00 70.63  ? 87  GLN A C   1 
ATOM 633  O O   . GLN A 1 87  ? 241.912 296.832 384.729 1.00 70.63  ? 87  GLN A O   1 
ATOM 634  C CB  . GLN A 1 87  ? 244.429 295.027 383.553 1.00 70.63  ? 87  GLN A CB  1 
ATOM 635  C CG  . GLN A 1 87  ? 245.022 293.691 383.161 1.00 70.63  ? 87  GLN A CG  1 
ATOM 636  C CD  . GLN A 1 87  ? 245.832 293.070 384.277 1.00 70.63  ? 87  GLN A CD  1 
ATOM 637  O OE1 . GLN A 1 87  ? 245.400 292.110 384.910 1.00 70.63  ? 87  GLN A OE1 1 
ATOM 638  N NE2 . GLN A 1 87  ? 247.016 293.615 384.523 1.00 70.63  ? 87  GLN A NE2 1 
ATOM 639  N N   . ALA A 1 88  ? 243.830 296.991 385.904 1.00 65.71  ? 88  ALA A N   1 
ATOM 640  C CA  . ALA A 1 88  ? 243.599 298.383 386.293 1.00 65.71  ? 88  ALA A CA  1 
ATOM 641  C C   . ALA A 1 88  ? 244.968 299.046 386.444 1.00 65.71  ? 88  ALA A C   1 
ATOM 642  O O   . ALA A 1 88  ? 245.571 299.014 387.517 1.00 65.71  ? 88  ALA A O   1 
ATOM 643  C CB  . ALA A 1 88  ? 242.788 298.483 387.574 1.00 65.71  ? 88  ALA A CB  1 
ATOM 644  N N   . TYR A 1 89  ? 245.438 299.654 385.363 1.00 65.25  ? 89  TYR A N   1 
ATOM 645  C CA  . TYR A 1 89  ? 246.725 300.322 385.403 1.00 65.25  ? 89  TYR A CA  1 
ATOM 646  C C   . TYR A 1 89  ? 246.585 301.687 386.067 1.00 65.25  ? 89  TYR A C   1 
ATOM 647  O O   . TYR A 1 89  ? 245.490 302.238 386.198 1.00 65.25  ? 89  TYR A O   1 
ATOM 648  C CB  . TYR A 1 89  ? 247.299 300.481 383.996 1.00 65.25  ? 89  TYR A CB  1 
ATOM 649  C CG  . TYR A 1 89  ? 247.397 299.200 383.199 1.00 65.25  ? 89  TYR A CG  1 
ATOM 650  C CD1 . TYR A 1 89  ? 247.494 299.232 381.816 1.00 65.25  ? 89  TYR A CD1 1 
ATOM 651  C CD2 . TYR A 1 89  ? 247.406 297.962 383.825 1.00 65.25  ? 89  TYR A CD2 1 
ATOM 652  C CE1 . TYR A 1 89  ? 247.584 298.071 381.080 1.00 65.25  ? 89  TYR A CE1 1 
ATOM 653  C CE2 . TYR A 1 89  ? 247.494 296.796 383.097 1.00 65.25  ? 89  TYR A CE2 1 
ATOM 654  C CZ  . TYR A 1 89  ? 247.585 296.856 381.726 1.00 65.25  ? 89  TYR A CZ  1 
ATOM 655  O OH  . TYR A 1 89  ? 247.677 295.695 380.996 1.00 65.25  ? 89  TYR A OH  1 
ATOM 656  N N   . ALA A 1 90  ? 247.719 302.232 386.495 1.00 61.77  ? 90  ALA A N   1 
ATOM 657  C CA  . ALA A 1 90  ? 247.763 303.604 386.993 1.00 61.77  ? 90  ALA A CA  1 
ATOM 658  C C   . ALA A 1 90  ? 249.208 304.068 386.900 1.00 61.77  ? 90  ALA A C   1 
ATOM 659  O O   . ALA A 1 90  ? 250.059 303.589 387.653 1.00 61.77  ? 90  ALA A O   1 
ATOM 660  C CB  . ALA A 1 90  ? 247.242 303.691 388.420 1.00 61.77  ? 90  ALA A CB  1 
ATOM 661  N N   . ASP A 1 91  ? 249.478 304.993 385.987 1.00 62.64  ? 91  ASP A N   1 
ATOM 662  C CA  . ASP A 1 91  ? 250.828 305.467 385.725 1.00 62.64  ? 91  ASP A CA  1 
ATOM 663  C C   . ASP A 1 91  ? 250.978 306.882 386.256 1.00 62.64  ? 91  ASP A C   1 
ATOM 664  O O   . ASP A 1 91  ? 250.157 307.754 385.956 1.00 62.64  ? 91  ASP A O   1 
ATOM 665  C CB  . ASP A 1 91  ? 251.136 305.426 384.228 1.00 62.64  ? 91  ASP A CB  1 
ATOM 666  C CG  . ASP A 1 91  ? 251.012 304.035 383.651 1.00 62.64  ? 91  ASP A CG  1 
ATOM 667  O OD1 . ASP A 1 91  ? 251.168 303.060 384.415 1.00 62.64  ? 91  ASP A OD1 1 
ATOM 668  O OD2 . ASP A 1 91  ? 250.757 303.914 382.434 1.00 62.64  ? 91  ASP A OD2 1 
ATOM 669  N N   . VAL A 1 92  ? 252.023 307.106 387.045 1.00 61.18  ? 92  VAL A N   1 
ATOM 670  C CA  . VAL A 1 92  ? 252.325 308.415 387.604 1.00 61.18  ? 92  VAL A CA  1 
ATOM 671  C C   . VAL A 1 92  ? 253.757 308.755 387.229 1.00 61.18  ? 92  VAL A C   1 
ATOM 672  O O   . VAL A 1 92  ? 254.691 308.064 387.651 1.00 61.18  ? 92  VAL A O   1 
ATOM 673  C CB  . VAL A 1 92  ? 252.143 308.444 389.129 1.00 61.18  ? 92  VAL A CB  1 
ATOM 674  C CG1 . VAL A 1 92  ? 252.669 309.742 389.697 1.00 61.18  ? 92  VAL A CG1 1 
ATOM 675  C CG2 . VAL A 1 92  ? 250.684 308.253 389.487 1.00 61.18  ? 92  VAL A CG2 1 
ATOM 676  N N   . THR A 1 93  ? 253.932 309.809 386.437 1.00 62.89  ? 93  THR A N   1 
ATOM 677  C CA  . THR A 1 93  ? 255.246 310.225 385.971 1.00 62.89  ? 93  THR A CA  1 
ATOM 678  C C   . THR A 1 93  ? 255.471 311.677 386.355 1.00 62.89  ? 93  THR A C   1 
ATOM 679  O O   . THR A 1 93  ? 254.602 312.523 386.123 1.00 62.89  ? 93  THR A O   1 
ATOM 680  C CB  . THR A 1 93  ? 255.383 310.063 384.455 1.00 62.89  ? 93  THR A CB  1 
ATOM 681  O OG1 . THR A 1 93  ? 254.572 311.042 383.798 1.00 62.89  ? 93  THR A OG1 1 
ATOM 682  C CG2 . THR A 1 93  ? 254.935 308.679 384.024 1.00 62.89  ? 93  THR A CG2 1 
ATOM 683  N N   . PHE A 1 94  ? 256.627 311.962 386.938 1.00 65.67  ? 94  PHE A N   1 
ATOM 684  C CA  . PHE A 1 94  ? 256.999 313.319 387.304 1.00 65.67  ? 94  PHE A CA  1 
ATOM 685  C C   . PHE A 1 94  ? 257.981 313.876 386.284 1.00 65.67  ? 94  PHE A C   1 
ATOM 686  O O   . PHE A 1 94  ? 258.351 313.216 385.310 1.00 65.67  ? 94  PHE A O   1 
ATOM 687  C CB  . PHE A 1 94  ? 257.612 313.370 388.709 1.00 65.67  ? 94  PHE A CB  1 
ATOM 688  C CG  . PHE A 1 94  ? 256.628 313.126 389.819 1.00 65.67  ? 94  PHE A CG  1 
ATOM 689  C CD1 . PHE A 1 94  ? 255.321 312.776 389.551 1.00 65.67  ? 94  PHE A CD1 1 
ATOM 690  C CD2 . PHE A 1 94  ? 257.016 313.266 391.138 1.00 65.67  ? 94  PHE A CD2 1 
ATOM 691  C CE1 . PHE A 1 94  ? 254.425 312.561 390.574 1.00 65.67  ? 94  PHE A CE1 1 
ATOM 692  C CE2 . PHE A 1 94  ? 256.122 313.050 392.164 1.00 65.67  ? 94  PHE A CE2 1 
ATOM 693  C CZ  . PHE A 1 94  ? 254.825 312.697 391.881 1.00 65.67  ? 94  PHE A CZ  1 
ATOM 694  N N   . SER A 1 95  ? 258.399 315.116 386.520 1.00 64.85  ? 95  SER A N   1 
ATOM 695  C CA  . SER A 1 95  ? 259.405 315.765 385.692 1.00 64.85  ? 95  SER A CA  1 
ATOM 696  C C   . SER A 1 95  ? 259.958 316.949 386.464 1.00 64.85  ? 95  SER A C   1 
ATOM 697  O O   . SER A 1 95  ? 259.192 317.794 386.932 1.00 64.85  ? 95  SER A O   1 
ATOM 698  C CB  . SER A 1 95  ? 258.819 316.223 384.354 1.00 64.85  ? 95  SER A CB  1 
ATOM 699  O OG  . SER A 1 95  ? 259.801 316.880 383.574 1.00 64.85  ? 95  SER A OG  1 
ATOM 700  N N   . PHE A 1 96  ? 261.278 317.008 386.593 1.00 68.67  ? 96  PHE A N   1 
ATOM 701  C CA  . PHE A 1 96  ? 261.935 318.028 387.395 1.00 68.67  ? 96  PHE A CA  1 
ATOM 702  C C   . PHE A 1 96  ? 263.149 318.565 386.655 1.00 68.67  ? 96  PHE A C   1 
ATOM 703  O O   . PHE A 1 96  ? 263.906 317.802 386.049 1.00 68.67  ? 96  PHE A O   1 
ATOM 704  C CB  . PHE A 1 96  ? 262.358 317.465 388.752 1.00 68.67  ? 96  PHE A CB  1 
ATOM 705  C CG  . PHE A 1 96  ? 261.211 317.190 389.675 1.00 68.67  ? 96  PHE A CG  1 
ATOM 706  C CD1 . PHE A 1 96  ? 260.190 318.107 389.822 1.00 68.67  ? 96  PHE A CD1 1 
ATOM 707  C CD2 . PHE A 1 96  ? 261.144 316.005 390.380 1.00 68.67  ? 96  PHE A CD2 1 
ATOM 708  C CE1 . PHE A 1 96  ? 259.134 317.853 390.669 1.00 68.67  ? 96  PHE A CE1 1 
ATOM 709  C CE2 . PHE A 1 96  ? 260.088 315.747 391.227 1.00 68.67  ? 96  PHE A CE2 1 
ATOM 710  C CZ  . PHE A 1 96  ? 259.082 316.671 391.369 1.00 68.67  ? 96  PHE A CZ  1 
ATOM 711  N N   . THR A 1 97  ? 263.327 319.880 386.708 1.00 73.08  ? 97  THR A N   1 
ATOM 712  C CA  . THR A 1 97  ? 264.500 320.510 386.127 1.00 73.08  ? 97  THR A CA  1 
ATOM 713  C C   . THR A 1 97  ? 265.680 320.377 387.084 1.00 73.08  ? 97  THR A C   1 
ATOM 714  O O   . THR A 1 97  ? 265.509 320.306 388.304 1.00 73.08  ? 97  THR A O   1 
ATOM 715  C CB  . THR A 1 97  ? 264.212 321.981 385.815 1.00 73.08  ? 97  THR A CB  1 
ATOM 716  O OG1 . THR A 1 97  ? 263.089 322.064 384.930 1.00 73.08  ? 97  THR A OG1 1 
ATOM 717  C CG2 . THR A 1 97  ? 265.401 322.646 385.138 1.00 73.08  ? 97  THR A CG2 1 
ATOM 718  N N   . GLN A 1 98  ? 266.886 320.328 386.512 1.00 78.98  ? 98  GLN A N   1 
ATOM 719  C CA  . GLN A 1 98  ? 268.086 320.084 387.307 1.00 78.98  ? 98  GLN A CA  1 
ATOM 720  C C   . GLN A 1 98  ? 268.229 321.094 388.438 1.00 78.98  ? 98  GLN A C   1 
ATOM 721  O O   . GLN A 1 98  ? 268.677 320.745 389.535 1.00 78.98  ? 98  GLN A O   1 
ATOM 722  C CB  . GLN A 1 98  ? 269.319 320.116 386.407 1.00 78.98  ? 98  GLN A CB  1 
ATOM 723  C CG  . GLN A 1 98  ? 269.294 319.086 385.294 1.00 78.98  ? 98  GLN A CG  1 
ATOM 724  C CD  . GLN A 1 98  ? 270.516 319.162 384.405 1.00 78.98  ? 98  GLN A CD  1 
ATOM 725  O OE1 . GLN A 1 98  ? 271.409 319.979 384.626 1.00 78.98  ? 98  GLN A OE1 1 
ATOM 726  N NE2 . GLN A 1 98  ? 270.562 318.309 383.388 1.00 78.98  ? 98  GLN A NE2 1 
ATOM 727  N N   . TYR A 1 99  ? 267.853 322.345 388.195 1.00 78.74  ? 99  TYR A N   1 
ATOM 728  C CA  . TYR A 1 99  ? 267.999 323.397 389.191 1.00 78.74  ? 99  TYR A CA  1 
ATOM 729  C C   . TYR A 1 99  ? 266.834 323.462 390.168 1.00 78.74  ? 99  TYR A C   1 
ATOM 730  O O   . TYR A 1 99  ? 266.871 324.277 391.095 1.00 78.74  ? 99  TYR A O   1 
ATOM 731  C CB  . TYR A 1 99  ? 268.165 324.756 388.505 1.00 78.74  ? 99  TYR A CB  1 
ATOM 732  C CG  . TYR A 1 99  ? 269.403 324.859 387.647 1.00 78.74  ? 99  TYR A CG  1 
ATOM 733  C CD1 . TYR A 1 99  ? 270.494 324.033 387.869 1.00 78.74  ? 99  TYR A CD1 1 
ATOM 734  C CD2 . TYR A 1 99  ? 269.478 325.777 386.612 1.00 78.74  ? 99  TYR A CD2 1 
ATOM 735  C CE1 . TYR A 1 99  ? 271.625 324.120 387.088 1.00 78.74  ? 99  TYR A CE1 1 
ATOM 736  C CE2 . TYR A 1 99  ? 270.607 325.871 385.824 1.00 78.74  ? 99  TYR A CE2 1 
ATOM 737  C CZ  . TYR A 1 99  ? 271.676 325.040 386.067 1.00 78.74  ? 99  TYR A CZ  1 
ATOM 738  O OH  . TYR A 1 99  ? 272.805 325.128 385.287 1.00 78.74  ? 99  TYR A OH  1 
ATOM 739  N N   . SER A 1 100 ? 265.809 322.633 389.988 1.00 75.47  ? 100 SER A N   1 
ATOM 740  C CA  . SER A 1 100 ? 264.651 322.676 390.871 1.00 75.47  ? 100 SER A CA  1 
ATOM 741  C C   . SER A 1 100 ? 265.032 322.215 392.271 1.00 75.47  ? 100 SER A C   1 
ATOM 742  O O   . SER A 1 100 ? 265.649 321.161 392.443 1.00 75.47  ? 100 SER A O   1 
ATOM 743  C CB  . SER A 1 100 ? 263.532 321.801 390.314 1.00 75.47  ? 100 SER A CB  1 
ATOM 744  O OG  . SER A 1 100 ? 263.952 320.453 390.206 1.00 75.47  ? 100 SER A OG  1 
ATOM 745  N N   . THR A 1 101 ? 264.649 323.000 393.273 1.00 79.33  ? 101 THR A N   1 
ATOM 746  C CA  . THR A 1 101 ? 264.982 322.690 394.652 1.00 79.33  ? 101 THR A CA  1 
ATOM 747  C C   . THR A 1 101 ? 264.085 321.573 395.178 1.00 79.33  ? 101 THR A C   1 
ATOM 748  O O   . THR A 1 101 ? 263.236 321.029 394.467 1.00 79.33  ? 101 THR A O   1 
ATOM 749  C CB  . THR A 1 101 ? 264.859 323.937 395.523 1.00 79.33  ? 101 THR A CB  1 
ATOM 750  O OG1 . THR A 1 101 ? 265.252 323.624 396.865 1.00 79.33  ? 101 THR A OG1 1 
ATOM 751  C CG2 . THR A 1 101 ? 263.428 324.439 395.527 1.00 79.33  ? 101 THR A CG2 1 
ATOM 752  N N   . ASP A 1 102 ? 264.283 321.216 396.449 1.00 86.91  ? 102 ASP A N   1 
ATOM 753  C CA  . ASP A 1 102 ? 263.449 320.186 397.058 1.00 86.91  ? 102 ASP A CA  1 
ATOM 754  C C   . ASP A 1 102 ? 262.065 320.716 397.410 1.00 86.91  ? 102 ASP A C   1 
ATOM 755  O O   . ASP A 1 102 ? 261.099 319.946 397.473 1.00 86.91  ? 102 ASP A O   1 
ATOM 756  C CB  . ASP A 1 102 ? 264.172 319.577 398.269 1.00 86.91  ? 102 ASP A CB  1 
ATOM 757  C CG  . ASP A 1 102 ? 264.038 320.398 399.566 1.00 86.91  ? 102 ASP A CG  1 
ATOM 758  O OD1 . ASP A 1 102 ? 264.798 320.086 400.506 1.00 86.91  ? 102 ASP A OD1 1 
ATOM 759  O OD2 . ASP A 1 102 ? 263.243 321.354 399.673 1.00 86.91  ? 102 ASP A OD2 1 
ATOM 760  N N   . GLU A 1 103 ? 261.953 322.022 397.656 1.00 89.22  ? 103 GLU A N   1 
ATOM 761  C CA  . GLU A 1 103 ? 260.667 322.602 398.029 1.00 89.22  ? 103 GLU A CA  1 
ATOM 762  C C   . GLU A 1 103 ? 259.617 322.361 396.953 1.00 89.22  ? 103 GLU A C   1 
ATOM 763  O O   . GLU A 1 103 ? 258.502 321.920 397.246 1.00 89.22  ? 103 GLU A O   1 
ATOM 764  C CB  . GLU A 1 103 ? 260.825 324.098 398.295 1.00 89.22  ? 103 GLU A CB  1 
ATOM 765  C CG  . GLU A 1 103 ? 259.542 324.781 398.730 1.00 89.22  ? 103 GLU A CG  1 
ATOM 766  C CD  . GLU A 1 103 ? 259.043 324.283 400.068 1.00 89.22  ? 103 GLU A CD  1 
ATOM 767  O OE1 . GLU A 1 103 ? 259.873 323.809 400.871 1.00 89.22  ? 103 GLU A OE1 1 
ATOM 768  O OE2 . GLU A 1 103 ? 257.821 324.361 400.316 1.00 89.22  ? 103 GLU A OE2 1 
ATOM 769  N N   . GLU A 1 104 ? 259.958 322.651 395.696 1.00 83.54  ? 104 GLU A N   1 
ATOM 770  C CA  . GLU A 1 104 ? 258.991 322.508 394.613 1.00 83.54  ? 104 GLU A CA  1 
ATOM 771  C C   . GLU A 1 104 ? 258.595 321.051 394.413 1.00 83.54  ? 104 GLU A C   1 
ATOM 772  O O   . GLU A 1 104 ? 257.413 320.742 394.218 1.00 83.54  ? 104 GLU A O   1 
ATOM 773  C CB  . GLU A 1 104 ? 259.573 323.093 393.331 1.00 83.54  ? 104 GLU A CB  1 
ATOM 774  C CG  . GLU A 1 104 ? 259.719 324.598 393.388 1.00 83.54  ? 104 GLU A CG  1 
ATOM 775  C CD  . GLU A 1 104 ? 260.784 325.117 392.448 1.00 83.54  ? 104 GLU A CD  1 
ATOM 776  O OE1 . GLU A 1 104 ? 260.646 326.258 391.966 1.00 83.54  ? 104 GLU A OE1 1 
ATOM 777  O OE2 . GLU A 1 104 ? 261.759 324.381 392.188 1.00 83.54  ? 104 GLU A OE2 1 
ATOM 778  N N   . ARG A 1 105 ? 259.571 320.144 394.455 1.00 76.21  ? 105 ARG A N   1 
ATOM 779  C CA  . ARG A 1 105 ? 259.273 318.726 394.291 1.00 76.21  ? 105 ARG A CA  1 
ATOM 780  C C   . ARG A 1 105 ? 258.360 318.230 395.404 1.00 76.21  ? 105 ARG A C   1 
ATOM 781  O O   . ARG A 1 105 ? 257.375 317.523 395.151 1.00 76.21  ? 105 ARG A O   1 
ATOM 782  C CB  . ARG A 1 105 ? 260.575 317.927 394.256 1.00 76.21  ? 105 ARG A CB  1 
ATOM 783  C CG  . ARG A 1 105 ? 261.553 318.400 393.193 1.00 76.21  ? 105 ARG A CG  1 
ATOM 784  C CD  . ARG A 1 105 ? 262.732 317.453 393.049 1.00 76.21  ? 105 ARG A CD  1 
ATOM 785  N NE  . ARG A 1 105 ? 263.602 317.460 394.219 1.00 76.21  ? 105 ARG A NE  1 
ATOM 786  C CZ  . ARG A 1 105 ? 264.661 318.244 394.354 1.00 76.21  ? 105 ARG A CZ  1 
ATOM 787  N NH1 . ARG A 1 105 ? 265.006 319.108 393.414 1.00 76.21  ? 105 ARG A NH1 1 
ATOM 788  N NH2 . ARG A 1 105 ? 265.396 318.156 395.458 1.00 76.21  ? 105 ARG A NH2 1 
ATOM 789  N N   . ALA A 1 106 ? 258.669 318.599 396.649 1.00 78.29  ? 106 ALA A N   1 
ATOM 790  C CA  . ALA A 1 106 ? 257.837 318.182 397.770 1.00 78.29  ? 106 ALA A CA  1 
ATOM 791  C C   . ALA A 1 106 ? 256.436 318.763 397.657 1.00 78.29  ? 106 ALA A C   1 
ATOM 792  O O   . ALA A 1 106 ? 255.449 318.083 397.961 1.00 78.29  ? 106 ALA A O   1 
ATOM 793  C CB  . ALA A 1 106 ? 258.484 318.595 399.090 1.00 78.29  ? 106 ALA A CB  1 
ATOM 794  N N   . PHE A 1 107 ? 256.331 320.022 397.228 1.00 78.41  ? 107 PHE A N   1 
ATOM 795  C CA  . PHE A 1 107 ? 255.023 320.638 397.057 1.00 78.41  ? 107 PHE A CA  1 
ATOM 796  C C   . PHE A 1 107 ? 254.206 319.908 396.003 1.00 78.41  ? 107 PHE A C   1 
ATOM 797  O O   . PHE A 1 107 ? 253.013 319.655 396.200 1.00 78.41  ? 107 PHE A O   1 
ATOM 798  C CB  . PHE A 1 107 ? 255.181 322.111 396.686 1.00 78.41  ? 107 PHE A CB  1 
ATOM 799  C CG  . PHE A 1 107 ? 253.883 322.850 396.593 1.00 78.41  ? 107 PHE A CG  1 
ATOM 800  C CD1 . PHE A 1 107 ? 253.264 323.331 397.732 1.00 78.41  ? 107 PHE A CD1 1 
ATOM 801  C CD2 . PHE A 1 107 ? 253.280 323.062 395.367 1.00 78.41  ? 107 PHE A CD2 1 
ATOM 802  C CE1 . PHE A 1 107 ? 252.067 324.010 397.649 1.00 78.41  ? 107 PHE A CE1 1 
ATOM 803  C CE2 . PHE A 1 107 ? 252.084 323.741 395.277 1.00 78.41  ? 107 PHE A CE2 1 
ATOM 804  C CZ  . PHE A 1 107 ? 251.477 324.215 396.419 1.00 78.41  ? 107 PHE A CZ  1 
ATOM 805  N N   . VAL A 1 108 ? 254.831 319.554 394.880 1.00 75.27  ? 108 VAL A N   1 
ATOM 806  C CA  . VAL A 1 108 ? 254.118 318.812 393.844 1.00 75.27  ? 108 VAL A CA  1 
ATOM 807  C C   . VAL A 1 108 ? 253.649 317.468 394.386 1.00 75.27  ? 108 VAL A C   1 
ATOM 808  O O   . VAL A 1 108 ? 252.497 317.062 394.182 1.00 75.27  ? 108 VAL A O   1 
ATOM 809  C CB  . VAL A 1 108 ? 255.005 318.638 392.599 1.00 75.27  ? 108 VAL A CB  1 
ATOM 810  C CG1 . VAL A 1 108 ? 254.395 317.619 391.656 1.00 75.27  ? 108 VAL A CG1 1 
ATOM 811  C CG2 . VAL A 1 108 ? 255.184 319.967 391.896 1.00 75.27  ? 108 VAL A CG2 1 
ATOM 812  N N   . ARG A 1 109 ? 254.533 316.764 395.097 1.00 75.76  ? 109 ARG A N   1 
ATOM 813  C CA  . ARG A 1 109 ? 254.180 315.445 395.612 1.00 75.76  ? 109 ARG A CA  1 
ATOM 814  C C   . ARG A 1 109 ? 253.006 315.526 396.579 1.00 75.76  ? 109 ARG A C   1 
ATOM 815  O O   . ARG A 1 109 ? 252.040 314.762 396.467 1.00 75.76  ? 109 ARG A O   1 
ATOM 816  C CB  . ARG A 1 109 ? 255.391 314.802 396.288 1.00 75.76  ? 109 ARG A CB  1 
ATOM 817  C CG  . ARG A 1 109 ? 255.076 313.501 397.004 1.00 75.76  ? 109 ARG A CG  1 
ATOM 818  C CD  . ARG A 1 109 ? 256.255 313.021 397.833 1.00 75.76  ? 109 ARG A CD  1 
ATOM 819  N NE  . ARG A 1 109 ? 256.583 313.932 398.922 1.00 75.76  ? 109 ARG A NE  1 
ATOM 820  C CZ  . ARG A 1 109 ? 255.914 314.007 400.064 1.00 75.76  ? 109 ARG A CZ  1 
ATOM 821  N NH1 . ARG A 1 109 ? 254.861 313.243 400.299 1.00 75.76  ? 109 ARG A NH1 1 
ATOM 822  N NH2 . ARG A 1 109 ? 256.315 314.865 400.996 1.00 75.76  ? 109 ARG A NH2 1 
ATOM 823  N N   . THR A 1 110 ? 253.059 316.462 397.526 1.00 79.84  ? 110 THR A N   1 
ATOM 824  C CA  . THR A 1 110 ? 251.991 316.540 398.516 1.00 79.84  ? 110 THR A CA  1 
ATOM 825  C C   . THR A 1 110 ? 250.697 317.071 397.911 1.00 79.84  ? 110 THR A C   1 
ATOM 826  O O   . THR A 1 110 ? 249.611 316.667 398.339 1.00 79.84  ? 110 THR A O   1 
ATOM 827  C CB  . THR A 1 110 ? 252.419 317.399 399.704 1.00 79.84  ? 110 THR A CB  1 
ATOM 828  O OG1 . THR A 1 110 ? 251.361 317.439 400.668 1.00 79.84  ? 110 THR A OG1 1 
ATOM 829  C CG2 . THR A 1 110 ? 252.731 318.801 399.258 1.00 79.84  ? 110 THR A CG2 1 
ATOM 830  N N   . GLU A 1 111 ? 250.780 317.959 396.917 1.00 77.39  ? 111 GLU A N   1 
ATOM 831  C CA  . GLU A 1 111 ? 249.568 318.413 396.248 1.00 77.39  ? 111 GLU A CA  1 
ATOM 832  C C   . GLU A 1 111 ? 248.899 317.272 395.499 1.00 77.39  ? 111 GLU A C   1 
ATOM 833  O O   . GLU A 1 111 ? 247.672 317.124 395.545 1.00 77.39  ? 111 GLU A O   1 
ATOM 834  C CB  . GLU A 1 111 ? 249.896 319.560 395.295 1.00 77.39  ? 111 GLU A CB  1 
ATOM 835  C CG  . GLU A 1 111 ? 248.690 320.161 394.602 1.00 77.39  ? 111 GLU A CG  1 
ATOM 836  C CD  . GLU A 1 111 ? 249.060 321.325 393.707 1.00 77.39  ? 111 GLU A CD  1 
ATOM 837  O OE1 . GLU A 1 111 ? 250.263 321.646 393.615 1.00 77.39  ? 111 GLU A OE1 1 
ATOM 838  O OE2 . GLU A 1 111 ? 248.150 321.922 393.095 1.00 77.39  ? 111 GLU A OE2 1 
ATOM 839  N N   . LEU A 1 112 ? 249.692 316.442 394.817 1.00 71.59  ? 112 LEU A N   1 
ATOM 840  C CA  . LEU A 1 112 ? 249.126 315.275 394.151 1.00 71.59  ? 112 LEU A CA  1 
ATOM 841  C C   . LEU A 1 112 ? 248.534 314.304 395.160 1.00 71.59  ? 112 LEU A C   1 
ATOM 842  O O   . LEU A 1 112 ? 247.489 313.694 394.905 1.00 71.59  ? 112 LEU A O   1 
ATOM 843  C CB  . LEU A 1 112 ? 250.190 314.584 393.305 1.00 71.59  ? 112 LEU A CB  1 
ATOM 844  C CG  . LEU A 1 112 ? 249.663 313.531 392.336 1.00 71.59  ? 112 LEU A CG  1 
ATOM 845  C CD1 . LEU A 1 112 ? 248.419 314.035 391.635 1.00 71.59  ? 112 LEU A CD1 1 
ATOM 846  C CD2 . LEU A 1 112 ? 250.735 313.176 391.333 1.00 71.59  ? 112 LEU A CD2 1 
ATOM 847  N N   . ALA A 1 113 ? 249.189 314.143 396.311 1.00 72.24  ? 113 ALA A N   1 
ATOM 848  C CA  . ALA A 1 113 ? 248.660 313.255 397.339 1.00 72.24  ? 113 ALA A CA  1 
ATOM 849  C C   . ALA A 1 113 ? 247.337 313.759 397.896 1.00 72.24  ? 113 ALA A C   1 
ATOM 850  O O   . ALA A 1 113 ? 246.420 312.963 398.122 1.00 72.24  ? 113 ALA A O   1 
ATOM 851  C CB  . ALA A 1 113 ? 249.676 313.091 398.467 1.00 72.24  ? 113 ALA A CB  1 
ATOM 852  N N   . ALA A 1 114 ? 247.218 315.063 398.122 1.00 70.21  ? 114 ALA A N   1 
ATOM 853  C CA  . ALA A 1 114 ? 245.999 315.619 398.693 1.00 70.21  ? 114 ALA A CA  1 
ATOM 854  C C   . ALA A 1 114 ? 244.865 315.727 397.688 1.00 70.21  ? 114 ALA A C   1 
ATOM 855  O O   . ALA A 1 114 ? 243.695 315.682 398.084 1.00 70.21  ? 114 ALA A O   1 
ATOM 856  C CB  . ALA A 1 114 ? 246.275 317.000 399.287 1.00 70.21  ? 114 ALA A CB  1 
ATOM 857  N N   . LEU A 1 115 ? 245.178 315.875 396.398 1.00 71.34  ? 115 LEU A N   1 
ATOM 858  C CA  . LEU A 1 115 ? 244.122 316.003 395.400 1.00 71.34  ? 115 LEU A CA  1 
ATOM 859  C C   . LEU A 1 115 ? 243.259 314.751 395.340 1.00 71.34  ? 115 LEU A C   1 
ATOM 860  O O   . LEU A 1 115 ? 242.035 314.839 395.192 1.00 71.34  ? 115 LEU A O   1 
ATOM 861  C CB  . LEU A 1 115 ? 244.727 316.297 394.030 1.00 71.34  ? 115 LEU A CB  1 
ATOM 862  C CG  . LEU A 1 115 ? 244.703 317.756 393.585 1.00 71.34  ? 115 LEU A CG  1 
ATOM 863  C CD1 . LEU A 1 115 ? 245.143 317.859 392.143 1.00 71.34  ? 115 LEU A CD1 1 
ATOM 864  C CD2 . LEU A 1 115 ? 243.316 318.338 393.765 1.00 71.34  ? 115 LEU A CD2 1 
ATOM 865  N N   . LEU A 1 116 ? 243.876 313.577 395.462 1.00 68.84  ? 116 LEU A N   1 
ATOM 866  C CA  . LEU A 1 116 ? 243.151 312.319 395.348 1.00 68.84  ? 116 LEU A CA  1 
ATOM 867  C C   . LEU A 1 116 ? 242.159 312.091 396.480 1.00 68.84  ? 116 LEU A C   1 
ATOM 868  O O   . LEU A 1 116 ? 241.485 311.056 396.483 1.00 68.84  ? 116 LEU A O   1 
ATOM 869  C CB  . LEU A 1 116 ? 244.142 311.159 395.279 1.00 68.84  ? 116 LEU A CB  1 
ATOM 870  C CG  . LEU A 1 116 ? 245.188 311.289 394.173 1.00 68.84  ? 116 LEU A CG  1 
ATOM 871  C CD1 . LEU A 1 116 ? 246.176 310.141 394.232 1.00 68.84  ? 116 LEU A CD1 1 
ATOM 872  C CD2 . LEU A 1 116 ? 244.522 311.352 392.814 1.00 68.84  ? 116 LEU A CD2 1 
ATOM 873  N N   . ALA A 1 117 ? 242.056 313.011 397.437 1.00 76.62  ? 117 ALA A N   1 
ATOM 874  C CA  . ALA A 1 117 ? 241.024 312.959 398.461 1.00 76.62  ? 117 ALA A CA  1 
ATOM 875  C C   . ALA A 1 117 ? 239.991 314.065 398.307 1.00 76.62  ? 117 ALA A C   1 
ATOM 876  O O   . ALA A 1 117 ? 239.025 314.105 399.077 1.00 76.62  ? 117 ALA A O   1 
ATOM 877  C CB  . ALA A 1 117 ? 241.655 313.027 399.856 1.00 76.62  ? 117 ALA A CB  1 
ATOM 878  N N   . SER A 1 118 ? 240.169 314.963 397.343 1.00 75.66  ? 118 SER A N   1 
ATOM 879  C CA  . SER A 1 118 ? 239.194 316.010 397.099 1.00 75.66  ? 118 SER A CA  1 
ATOM 880  C C   . SER A 1 118 ? 237.922 315.418 396.493 1.00 75.66  ? 118 SER A C   1 
ATOM 881  O O   . SER A 1 118 ? 237.980 314.420 395.770 1.00 75.66  ? 118 SER A O   1 
ATOM 882  C CB  . SER A 1 118 ? 239.776 317.064 396.162 1.00 75.66  ? 118 SER A CB  1 
ATOM 883  O OG  . SER A 1 118 ? 238.837 318.084 395.879 1.00 75.66  ? 118 SER A OG  1 
ATOM 884  N N   . PRO A 1 119 ? 236.758 316.015 396.774 1.00 79.31  ? 119 PRO A N   1 
ATOM 885  C CA  . PRO A 1 119 ? 235.508 315.467 396.216 1.00 79.31  ? 119 PRO A CA  1 
ATOM 886  C C   . PRO A 1 119 ? 235.510 315.367 394.701 1.00 79.31  ? 119 PRO A C   1 
ATOM 887  O O   . PRO A 1 119 ? 234.973 314.397 394.144 1.00 79.31  ? 119 PRO A O   1 
ATOM 888  C CB  . PRO A 1 119 ? 234.439 316.447 396.727 1.00 79.31  ? 119 PRO A CB  1 
ATOM 889  C CG  . PRO A 1 119 ? 235.195 317.665 397.167 1.00 79.31  ? 119 PRO A CG  1 
ATOM 890  C CD  . PRO A 1 119 ? 236.501 317.152 397.670 1.00 79.31  ? 119 PRO A CD  1 
ATOM 891  N N   . LEU A 1 120 ? 236.121 316.338 394.019 1.00 80.99  ? 120 LEU A N   1 
ATOM 892  C CA  . LEU A 1 120 ? 236.166 316.311 392.562 1.00 80.99  ? 120 LEU A CA  1 
ATOM 893  C C   . LEU A 1 120 ? 236.805 315.025 392.057 1.00 80.99  ? 120 LEU A C   1 
ATOM 894  O O   . LEU A 1 120 ? 236.235 314.324 391.212 1.00 80.99  ? 120 LEU A O   1 
ATOM 895  C CB  . LEU A 1 120 ? 236.926 317.536 392.047 1.00 80.99  ? 120 LEU A CB  1 
ATOM 896  C CG  . LEU A 1 120 ? 236.969 317.837 390.547 1.00 80.99  ? 120 LEU A CG  1 
ATOM 897  C CD1 . LEU A 1 120 ? 237.160 319.326 390.338 1.00 80.99  ? 120 LEU A CD1 1 
ATOM 898  C CD2 . LEU A 1 120 ? 238.088 317.076 389.850 1.00 80.99  ? 120 LEU A CD2 1 
ATOM 899  N N   . LEU A 1 121 ? 237.986 314.687 392.577 1.00 78.44  ? 121 LEU A N   1 
ATOM 900  C CA  . LEU A 1 121 ? 238.703 313.529 392.056 1.00 78.44  ? 121 LEU A CA  1 
ATOM 901  C C   . LEU A 1 121 ? 238.040 312.220 392.463 1.00 78.44  ? 121 LEU A C   1 
ATOM 902  O O   . LEU A 1 121 ? 237.988 311.279 391.663 1.00 78.44  ? 121 LEU A O   1 
ATOM 903  C CB  . LEU A 1 121 ? 240.161 313.560 392.503 1.00 78.44  ? 121 LEU A CB  1 
ATOM 904  C CG  . LEU A 1 121 ? 241.048 314.403 391.590 1.00 78.44  ? 121 LEU A CG  1 
ATOM 905  C CD1 . LEU A 1 121 ? 242.500 314.310 392.008 1.00 78.44  ? 121 LEU A CD1 1 
ATOM 906  C CD2 . LEU A 1 121 ? 240.876 313.961 390.148 1.00 78.44  ? 121 LEU A CD2 1 
ATOM 907  N N   . ILE A 1 122 ? 237.532 312.126 393.694 1.00 79.31  ? 122 ILE A N   1 
ATOM 908  C CA  . ILE A 1 122 ? 236.907 310.866 394.080 1.00 79.31  ? 122 ILE A CA  1 
ATOM 909  C C   . ILE A 1 122 ? 235.660 310.628 393.247 1.00 79.31  ? 122 ILE A C   1 
ATOM 910  O O   . ILE A 1 122 ? 235.364 309.485 392.876 1.00 79.31  ? 122 ILE A O   1 
ATOM 911  C CB  . ILE A 1 122 ? 236.585 310.815 395.584 1.00 79.31  ? 122 ILE A CB  1 
ATOM 912  C CG1 . ILE A 1 122 ? 235.871 312.078 396.036 1.00 79.31  ? 122 ILE A CG1 1 
ATOM 913  C CG2 . ILE A 1 122 ? 237.853 310.662 396.388 1.00 79.31  ? 122 ILE A CG2 1 
ATOM 914  C CD1 . ILE A 1 122 ? 235.200 311.944 397.383 1.00 79.31  ? 122 ILE A CD1 1 
ATOM 915  N N   . ASP A 1 123 ? 234.914 311.688 392.921 1.00 82.44  ? 123 ASP A N   1 
ATOM 916  C CA  . ASP A 1 123 ? 233.760 311.504 392.050 1.00 82.44  ? 123 ASP A CA  1 
ATOM 917  C C   . ASP A 1 123 ? 234.215 311.136 390.641 1.00 82.44  ? 123 ASP A C   1 
ATOM 918  O O   . ASP A 1 123 ? 233.684 310.196 390.038 1.00 82.44  ? 123 ASP A O   1 
ATOM 919  C CB  . ASP A 1 123 ? 232.900 312.775 392.063 1.00 82.44  ? 123 ASP A CB  1 
ATOM 920  C CG  . ASP A 1 123 ? 231.799 312.793 390.994 1.00 82.44  ? 123 ASP A CG  1 
ATOM 921  O OD1 . ASP A 1 123 ? 231.629 311.835 390.214 1.00 82.44  ? 123 ASP A OD1 1 
ATOM 922  O OD2 . ASP A 1 123 ? 231.068 313.801 390.947 1.00 82.44  ? 123 ASP A OD2 1 
ATOM 923  N N   . ALA A 1 124 ? 235.224 311.834 390.115 1.00 76.09  ? 124 ALA A N   1 
ATOM 924  C CA  . ALA A 1 124 ? 235.682 311.566 388.757 1.00 76.09  ? 124 ALA A CA  1 
ATOM 925  C C   . ALA A 1 124 ? 236.343 310.202 388.617 1.00 76.09  ? 124 ALA A C   1 
ATOM 926  O O   . ALA A 1 124 ? 236.540 309.738 387.490 1.00 76.09  ? 124 ALA A O   1 
ATOM 927  C CB  . ALA A 1 124 ? 236.651 312.657 388.305 1.00 76.09  ? 124 ALA A CB  1 
ATOM 928  N N   . ILE A 1 125 ? 236.704 309.561 389.722 1.00 77.17  ? 125 ILE A N   1 
ATOM 929  C CA  . ILE A 1 125 ? 237.321 308.240 389.691 1.00 77.17  ? 125 ILE A CA  1 
ATOM 930  C C   . ILE A 1 125 ? 236.305 307.135 389.945 1.00 77.17  ? 125 ILE A C   1 
ATOM 931  O O   . ILE A 1 125 ? 236.231 306.167 389.190 1.00 77.17  ? 125 ILE A O   1 
ATOM 932  C CB  . ILE A 1 125 ? 238.486 308.171 390.702 1.00 77.17  ? 125 ILE A CB  1 
ATOM 933  C CG1 . ILE A 1 125 ? 239.674 308.979 390.192 1.00 77.17  ? 125 ILE A CG1 1 
ATOM 934  C CG2 . ILE A 1 125 ? 238.893 306.733 390.944 1.00 77.17  ? 125 ILE A CG2 1 
ATOM 935  C CD1 . ILE A 1 125 ? 240.220 308.469 388.888 1.00 77.17  ? 125 ILE A CD1 1 
ATOM 936  N N   . ASP A 1 126 ? 235.514 307.260 391.012 1.00 80.61  ? 126 ASP A N   1 
ATOM 937  C CA  . ASP A 1 126 ? 234.616 306.175 391.397 1.00 80.61  ? 126 ASP A CA  1 
ATOM 938  C C   . ASP A 1 126 ? 233.532 305.948 390.350 1.00 80.61  ? 126 ASP A C   1 
ATOM 939  O O   . ASP A 1 126 ? 233.311 304.815 389.909 1.00 80.61  ? 126 ASP A O   1 
ATOM 940  C CB  . ASP A 1 126 ? 233.999 306.473 392.762 1.00 80.61  ? 126 ASP A CB  1 
ATOM 941  C CG  . ASP A 1 126 ? 234.944 306.167 393.904 1.00 80.61  ? 126 ASP A CG  1 
ATOM 942  O OD1 . ASP A 1 126 ? 236.157 306.024 393.645 1.00 80.61  ? 126 ASP A OD1 1 
ATOM 943  O OD2 . ASP A 1 126 ? 234.476 306.069 395.057 1.00 80.61  ? 126 ASP A OD2 1 
ATOM 944  N N   . GLN A 1 127 ? 232.848 307.013 389.935 1.00 83.91  ? 127 GLN A N   1 
ATOM 945  C CA  . GLN A 1 127 ? 231.782 306.906 388.950 1.00 83.91  ? 127 GLN A CA  1 
ATOM 946  C C   . GLN A 1 127 ? 232.184 307.391 387.566 1.00 83.91  ? 127 GLN A C   1 
ATOM 947  O O   . GLN A 1 127 ? 231.409 307.215 386.620 1.00 83.91  ? 127 GLN A O   1 
ATOM 948  C CB  . GLN A 1 127 ? 230.545 307.687 389.414 1.00 83.91  ? 127 GLN A CB  1 
ATOM 949  C CG  . GLN A 1 127 ? 229.751 306.999 390.506 1.00 83.91  ? 127 GLN A CG  1 
ATOM 950  C CD  . GLN A 1 127 ? 230.339 307.225 391.879 1.00 83.91  ? 127 GLN A CD  1 
ATOM 951  O OE1 . GLN A 1 127 ? 231.173 308.109 392.070 1.00 83.91  ? 127 GLN A OE1 1 
ATOM 952  N NE2 . GLN A 1 127 ? 229.906 306.428 392.847 1.00 83.91  ? 127 GLN A NE2 1 
ATOM 953  N N   . LEU A 1 128 ? 233.365 307.992 387.424 1.00 75.60  ? 128 LEU A N   1 
ATOM 954  C CA  . LEU A 1 128 ? 233.869 308.497 386.149 1.00 75.60  ? 128 LEU A CA  1 
ATOM 955  C C   . LEU A 1 128 ? 232.883 309.495 385.534 1.00 75.60  ? 128 LEU A C   1 
ATOM 956  O O   . LEU A 1 128 ? 232.352 309.311 384.438 1.00 75.60  ? 128 LEU A O   1 
ATOM 957  C CB  . LEU A 1 128 ? 234.172 307.345 385.186 1.00 75.60  ? 128 LEU A CB  1 
ATOM 958  C CG  . LEU A 1 128 ? 235.177 306.336 385.740 1.00 75.60  ? 128 LEU A CG  1 
ATOM 959  C CD1 . LEU A 1 128 ? 234.463 305.094 386.248 1.00 75.60  ? 128 LEU A CD1 1 
ATOM 960  C CD2 . LEU A 1 128 ? 236.233 305.985 384.714 1.00 75.60  ? 128 LEU A CD2 1 
ATOM 961  N N   . ASN A 1 129 ? 232.652 310.562 386.287 1.00 76.11  ? 129 ASN A N   1 
ATOM 962  C CA  . ASN A 1 129 ? 231.809 311.669 385.843 1.00 76.11  ? 129 ASN A CA  1 
ATOM 963  C C   . ASN A 1 129 ? 232.677 312.899 385.648 1.00 76.11  ? 129 ASN A C   1 
ATOM 964  O O   . ASN A 1 129 ? 233.248 313.411 386.630 1.00 76.11  ? 129 ASN A O   1 
ATOM 965  C CB  . ASN A 1 129 ? 230.699 311.953 386.853 1.00 76.11  ? 129 ASN A CB  1 
ATOM 966  C CG  . ASN A 1 129 ? 229.845 310.736 387.133 1.00 76.11  ? 129 ASN A CG  1 
ATOM 967  O OD1 . ASN A 1 129 ? 229.613 309.909 386.251 1.00 76.11  ? 129 ASN A OD1 1 
ATOM 968  N ND2 . ASN A 1 129 ? 229.365 310.622 388.365 1.00 76.11  ? 129 ASN A ND2 1 
ATOM 969  N N   . PRO A 1 130 ? 232.813 313.410 384.432 1.00 68.93  ? 130 PRO A N   1 
ATOM 970  C CA  . PRO A 1 130 ? 233.685 314.570 384.210 1.00 68.93  ? 130 PRO A CA  1 
ATOM 971  C C   . PRO A 1 130 ? 233.133 315.837 384.838 1.00 68.93  ? 130 PRO A C   1 
ATOM 972  O O   . PRO A 1 130 ? 232.106 315.808 385.522 1.00 68.93  ? 130 PRO A O   1 
ATOM 973  C CB  . PRO A 1 130 ? 233.737 314.692 382.680 1.00 68.93  ? 130 PRO A CB  1 
ATOM 974  C CG  . PRO A 1 130 ? 233.138 313.429 382.153 1.00 68.93  ? 130 PRO A CG  1 
ATOM 975  C CD  . PRO A 1 130 ? 232.192 312.939 383.188 1.00 68.93  ? 130 PRO A CD  1 
ATOM 976  N N   . ALA A 1 131 ? 233.811 316.954 384.612 1.00 72.58  ? 131 ALA A N   1 
ATOM 977  C CA  . ALA A 1 131 ? 233.329 318.236 385.099 1.00 72.58  ? 131 ALA A CA  1 
ATOM 978  C C   . ALA A 1 131 ? 232.328 318.834 384.115 1.00 72.58  ? 131 ALA A C   1 
ATOM 979  O O   . ALA A 1 131 ? 231.476 319.638 384.490 1.00 72.58  ? 131 ALA A O   1 
ATOM 980  C CB  . ALA A 1 131 ? 234.487 319.184 385.327 1.00 72.58  ? 131 ALA A CB  1 
ATOM 981  N N   . ALA B 1 1   ? 230.560 315.552 389.576 1.00 78.40  ? 1   ALA B N   1 
ATOM 982  C CA  . ALA B 1 1   ? 230.413 316.874 390.172 1.00 78.40  ? 1   ALA B CA  1 
ATOM 983  C C   . ALA B 1 1   ? 230.933 317.949 389.232 1.00 78.40  ? 1   ALA B C   1 
ATOM 984  O O   . ALA B 1 1   ? 231.579 317.651 388.229 1.00 78.40  ? 1   ALA B O   1 
ATOM 985  C CB  . ALA B 1 1   ? 231.138 316.943 391.505 1.00 78.40  ? 1   ALA B CB  1 
ATOM 986  N N   . LYS B 1 2   ? 230.650 319.202 389.566 1.00 75.62  ? 2   LYS B N   1 
ATOM 987  C CA  . LYS B 1 2   ? 231.078 320.342 388.774 1.00 75.62  ? 2   LYS B CA  1 
ATOM 988  C C   . LYS B 1 2   ? 232.319 320.967 389.395 1.00 75.62  ? 2   LYS B C   1 
ATOM 989  O O   . LYS B 1 2   ? 232.908 320.436 390.339 1.00 75.62  ? 2   LYS B O   1 
ATOM 990  C CB  . LYS B 1 2   ? 229.951 321.374 388.654 1.00 75.62  ? 2   LYS B CB  1 
ATOM 991  C CG  . LYS B 1 2   ? 228.660 320.839 388.037 1.00 75.62  ? 2   LYS B CG  1 
ATOM 992  C CD  . LYS B 1 2   ? 228.814 320.529 386.551 1.00 75.62  ? 2   LYS B CD  1 
ATOM 993  C CE  . LYS B 1 2   ? 228.996 319.040 386.294 1.00 75.62  ? 2   LYS B CE  1 
ATOM 994  N NZ  . LYS B 1 2   ? 229.082 318.740 384.840 1.00 75.62  ? 2   LYS B NZ  1 
ATOM 995  N N   . LEU B 1 3   ? 232.722 322.105 388.841 1.00 80.01  ? 3   LEU B N   1 
ATOM 996  C CA  . LEU B 1 3   ? 233.920 322.789 389.304 1.00 80.01  ? 3   LEU B CA  1 
ATOM 997  C C   . LEU B 1 3   ? 233.561 323.859 390.323 1.00 80.01  ? 3   LEU B C   1 
ATOM 998  O O   . LEU B 1 3   ? 232.704 324.711 390.068 1.00 80.01  ? 3   LEU B O   1 
ATOM 999  C CB  . LEU B 1 3   ? 234.661 323.414 388.125 1.00 80.01  ? 3   LEU B CB  1 
ATOM 1000 C CG  . LEU B 1 3   ? 235.075 322.444 387.024 1.00 80.01  ? 3   LEU B CG  1 
ATOM 1001 C CD1 . LEU B 1 3   ? 235.454 323.206 385.771 1.00 80.01  ? 3   LEU B CD1 1 
ATOM 1002 C CD2 . LEU B 1 3   ? 236.227 321.578 387.496 1.00 80.01  ? 3   LEU B CD2 1 
ATOM 1003 N N   . GLU B 1 4   ? 234.214 323.812 391.480 1.00 84.60  ? 4   GLU B N   1 
ATOM 1004 C CA  . GLU B 1 4   ? 234.060 324.837 392.502 1.00 84.60  ? 4   GLU B CA  1 
ATOM 1005 C C   . GLU B 1 4   ? 235.450 325.216 392.996 1.00 84.60  ? 4   GLU B C   1 
ATOM 1006 O O   . GLU B 1 4   ? 236.466 324.770 392.456 1.00 84.60  ? 4   GLU B O   1 
ATOM 1007 C CB  . GLU B 1 4   ? 233.152 324.355 393.642 1.00 84.60  ? 4   GLU B CB  1 
ATOM 1008 C CG  . GLU B 1 4   ? 231.700 324.140 393.244 1.00 84.60  ? 4   GLU B CG  1 
ATOM 1009 C CD  . GLU B 1 4   ? 231.469 322.792 392.595 1.00 84.60  ? 4   GLU B CD  1 
ATOM 1010 O OE1 . GLU B 1 4   ? 232.432 322.002 392.516 1.00 84.60  ? 4   GLU B OE1 1 
ATOM 1011 O OE2 . GLU B 1 4   ? 230.329 322.523 392.161 1.00 84.60  ? 4   GLU B OE2 1 
ATOM 1012 N N   . THR B 1 5   ? 235.499 326.045 394.036 1.00 81.20  ? 5   THR B N   1 
ATOM 1013 C CA  . THR B 1 5   ? 236.780 326.454 394.595 1.00 81.20  ? 5   THR B CA  1 
ATOM 1014 C C   . THR B 1 5   ? 237.409 325.301 395.362 1.00 81.20  ? 5   THR B C   1 
ATOM 1015 O O   . THR B 1 5   ? 237.154 325.130 396.558 1.00 81.20  ? 5   THR B O   1 
ATOM 1016 C CB  . THR B 1 5   ? 236.614 327.668 395.510 1.00 81.20  ? 5   THR B CB  1 
ATOM 1017 O OG1 . THR B 1 5   ? 235.782 327.318 396.622 1.00 81.20  ? 5   THR B OG1 1 
ATOM 1018 C CG2 . THR B 1 5   ? 235.977 328.819 394.753 1.00 81.20  ? 5   THR B CG2 1 
ATOM 1019 N N   . VAL B 1 6   ? 238.235 324.507 394.685 1.00 83.27  ? 6   VAL B N   1 
ATOM 1020 C CA  . VAL B 1 6   ? 238.900 323.387 395.337 1.00 83.27  ? 6   VAL B CA  1 
ATOM 1021 C C   . VAL B 1 6   ? 239.994 323.934 396.243 1.00 83.27  ? 6   VAL B C   1 
ATOM 1022 O O   . VAL B 1 6   ? 240.987 324.498 395.770 1.00 83.27  ? 6   VAL B O   1 
ATOM 1023 C CB  . VAL B 1 6   ? 239.471 322.409 394.304 1.00 83.27  ? 6   VAL B CB  1 
ATOM 1024 C CG1 . VAL B 1 6   ? 240.152 321.247 395.001 1.00 83.27  ? 6   VAL B CG1 1 
ATOM 1025 C CG2 . VAL B 1 6   ? 238.372 321.916 393.383 1.00 83.27  ? 6   VAL B CG2 1 
ATOM 1026 N N   . THR B 1 7   ? 239.817 323.770 397.549 1.00 87.21  ? 7   THR B N   1 
ATOM 1027 C CA  . THR B 1 7   ? 240.745 324.296 398.541 1.00 87.21  ? 7   THR B CA  1 
ATOM 1028 C C   . THR B 1 7   ? 241.506 323.141 399.179 1.00 87.21  ? 7   THR B C   1 
ATOM 1029 O O   . THR B 1 7   ? 240.925 322.089 399.464 1.00 87.21  ? 7   THR B O   1 
ATOM 1030 C CB  . THR B 1 7   ? 240.010 325.123 399.599 1.00 87.21  ? 7   THR B CB  1 
ATOM 1031 O OG1 . THR B 1 7   ? 240.952 325.642 400.546 1.00 87.21  ? 7   THR B OG1 1 
ATOM 1032 C CG2 . THR B 1 7   ? 238.963 324.289 400.322 1.00 87.21  ? 7   THR B CG2 1 
ATOM 1033 N N   . LEU B 1 8   ? 242.807 323.329 399.369 1.00 91.32  ? 8   LEU B N   1 
ATOM 1034 C CA  . LEU B 1 8   ? 243.671 322.335 399.987 1.00 91.32  ? 8   LEU B CA  1 
ATOM 1035 C C   . LEU B 1 8   ? 244.419 322.977 401.146 1.00 91.32  ? 8   LEU B C   1 
ATOM 1036 O O   . LEU B 1 8   ? 245.000 324.057 400.991 1.00 91.32  ? 8   LEU B O   1 
ATOM 1037 C CB  . LEU B 1 8   ? 244.655 321.763 398.966 1.00 91.32  ? 8   LEU B CB  1 
ATOM 1038 C CG  . LEU B 1 8   ? 244.004 320.985 397.825 1.00 91.32  ? 8   LEU B CG  1 
ATOM 1039 C CD1 . LEU B 1 8   ? 244.980 320.787 396.684 1.00 91.32  ? 8   LEU B CD1 1 
ATOM 1040 C CD2 . LEU B 1 8   ? 243.489 319.651 398.329 1.00 91.32  ? 8   LEU B CD2 1 
ATOM 1041 N N   . GLY B 1 9   ? 244.403 322.314 402.302 1.00 104.30 ? 9   GLY B N   1 
ATOM 1042 C CA  . GLY B 1 9   ? 245.036 322.846 403.486 1.00 104.30 ? 9   GLY B CA  1 
ATOM 1043 C C   . GLY B 1 9   ? 246.035 321.865 404.066 1.00 104.30 ? 9   GLY B C   1 
ATOM 1044 O O   . GLY B 1 9   ? 245.976 320.660 403.819 1.00 104.30 ? 9   GLY B O   1 
ATOM 1045 N N   . ASN B 1 10  ? 246.961 322.412 404.855 1.00 110.28 ? 10  ASN B N   1 
ATOM 1046 C CA  . ASN B 1 10  ? 248.027 321.639 405.490 1.00 110.28 ? 10  ASN B CA  1 
ATOM 1047 C C   . ASN B 1 10  ? 248.828 320.866 404.441 1.00 110.28 ? 10  ASN B C   1 
ATOM 1048 O O   . ASN B 1 10  ? 248.869 319.634 404.424 1.00 110.28 ? 10  ASN B O   1 
ATOM 1049 C CB  . ASN B 1 10  ? 247.455 320.704 406.559 1.00 110.28 ? 10  ASN B CB  1 
ATOM 1050 C CG  . ASN B 1 10  ? 246.940 321.452 407.770 1.00 110.28 ? 10  ASN B CG  1 
ATOM 1051 O OD1 . ASN B 1 10  ? 247.566 322.400 408.241 1.00 110.28 ? 10  ASN B OD1 1 
ATOM 1052 N ND2 . ASN B 1 10  ? 245.790 321.031 408.281 1.00 110.28 ? 10  ASN B ND2 1 
ATOM 1053 N N   . ILE B 1 11  ? 249.466 321.624 403.554 1.00 105.22 ? 11  ILE B N   1 
ATOM 1054 C CA  . ILE B 1 11  ? 250.094 321.083 402.357 1.00 105.22 ? 11  ILE B CA  1 
ATOM 1055 C C   . ILE B 1 11  ? 251.527 321.586 402.272 1.00 105.22 ? 11  ILE B C   1 
ATOM 1056 O O   . ILE B 1 11  ? 251.797 322.764 402.530 1.00 105.22 ? 11  ILE B O   1 
ATOM 1057 C CB  . ILE B 1 11  ? 249.304 321.478 401.094 1.00 105.22 ? 11  ILE B CB  1 
ATOM 1058 C CG1 . ILE B 1 11  ? 247.873 320.960 401.197 1.00 105.22 ? 11  ILE B CG1 1 
ATOM 1059 C CG2 . ILE B 1 11  ? 249.970 320.943 399.846 1.00 105.22 ? 11  ILE B CG2 1 
ATOM 1060 C CD1 . ILE B 1 11  ? 247.793 319.467 401.304 1.00 105.22 ? 11  ILE B CD1 1 
ATOM 1061 N N   . GLY B 1 12  ? 252.445 320.693 401.921 1.00 101.44 ? 12  GLY B N   1 
ATOM 1062 C CA  . GLY B 1 12  ? 253.812 321.087 401.650 1.00 101.44 ? 12  GLY B CA  1 
ATOM 1063 C C   . GLY B 1 12  ? 254.772 320.759 402.772 1.00 101.44 ? 12  GLY B C   1 
ATOM 1064 O O   . GLY B 1 12  ? 254.441 320.117 403.773 1.00 101.44 ? 12  GLY B O   1 
ATOM 1065 N N   . LYS B 1 13  ? 256.009 321.212 402.577 1.00 107.00 ? 13  LYS B N   1 
ATOM 1066 C CA  . LYS B 1 13  ? 257.025 321.094 403.611 1.00 107.00 ? 13  LYS B CA  1 
ATOM 1067 C C   . LYS B 1 13  ? 256.558 321.791 404.880 1.00 107.00 ? 13  LYS B C   1 
ATOM 1068 O O   . LYS B 1 13  ? 255.954 322.865 404.828 1.00 107.00 ? 13  LYS B O   1 
ATOM 1069 C CB  . LYS B 1 13  ? 258.342 321.703 403.130 1.00 107.00 ? 13  LYS B CB  1 
ATOM 1070 C CG  . LYS B 1 13  ? 258.973 320.966 401.966 1.00 107.00 ? 13  LYS B CG  1 
ATOM 1071 C CD  . LYS B 1 13  ? 260.188 320.174 402.408 1.00 107.00 ? 13  LYS B CD  1 
ATOM 1072 C CE  . LYS B 1 13  ? 261.449 321.020 402.355 1.00 107.00 ? 13  LYS B CE  1 
ATOM 1073 N NZ  . LYS B 1 13  ? 262.664 320.227 402.688 1.00 107.00 ? 13  LYS B NZ  1 
ATOM 1074 N N   . ASP B 1 14  ? 256.805 321.138 406.017 1.00 120.22 ? 14  ASP B N   1 
ATOM 1075 C CA  . ASP B 1 14  ? 256.404 321.606 407.342 1.00 120.22 ? 14  ASP B CA  1 
ATOM 1076 C C   . ASP B 1 14  ? 254.896 321.484 407.528 1.00 120.22 ? 14  ASP B C   1 
ATOM 1077 O O   . ASP B 1 14  ? 254.381 321.724 408.624 1.00 120.22 ? 14  ASP B O   1 
ATOM 1078 C CB  . ASP B 1 14  ? 256.864 323.048 407.587 1.00 120.22 ? 14  ASP B CB  1 
ATOM 1079 C CG  . ASP B 1 14  ? 258.372 323.198 407.524 1.00 120.22 ? 14  ASP B CG  1 
ATOM 1080 O OD1 . ASP B 1 14  ? 259.082 322.203 407.776 1.00 120.22 ? 14  ASP B OD1 1 
ATOM 1081 O OD2 . ASP B 1 14  ? 258.849 324.312 407.224 1.00 120.22 ? 14  ASP B OD2 1 
ATOM 1082 N N   . GLY B 1 15  ? 254.185 321.101 406.471 1.00 113.96 ? 15  GLY B N   1 
ATOM 1083 C CA  . GLY B 1 15  ? 252.757 320.838 406.565 1.00 113.96 ? 15  GLY B CA  1 
ATOM 1084 C C   . GLY B 1 15  ? 251.919 322.007 407.036 1.00 113.96 ? 15  GLY B C   1 
ATOM 1085 O O   . GLY B 1 15  ? 250.998 321.821 407.840 1.00 113.96 ? 15  GLY B O   1 
ATOM 1086 N N   . LYS B 1 16  ? 252.216 323.214 406.555 1.00 110.75 ? 16  LYS B N   1 
ATOM 1087 C CA  . LYS B 1 16  ? 251.448 324.396 406.928 1.00 110.75 ? 16  LYS B CA  1 
ATOM 1088 C C   . LYS B 1 16  ? 250.933 325.209 405.752 1.00 110.75 ? 16  LYS B C   1 
ATOM 1089 O O   . LYS B 1 16  ? 249.931 325.914 405.915 1.00 110.75 ? 16  LYS B O   1 
ATOM 1090 C CB  . LYS B 1 16  ? 252.279 325.320 407.830 1.00 110.75 ? 16  LYS B CB  1 
ATOM 1091 C CG  . LYS B 1 16  ? 253.004 324.610 408.956 1.00 110.75 ? 16  LYS B CG  1 
ATOM 1092 C CD  . LYS B 1 16  ? 254.260 325.360 409.358 1.00 110.75 ? 16  LYS B CD  1 
ATOM 1093 C CE  . LYS B 1 16  ? 253.920 326.653 410.078 1.00 110.75 ? 16  LYS B CE  1 
ATOM 1094 N NZ  . LYS B 1 16  ? 252.996 326.420 411.221 1.00 110.75 ? 16  LYS B NZ  1 
ATOM 1095 N N   . GLN B 1 17  ? 251.570 325.145 404.587 1.00 111.96 ? 17  GLN B N   1 
ATOM 1096 C CA  . GLN B 1 17  ? 251.131 325.942 403.451 1.00 111.96 ? 17  GLN B CA  1 
ATOM 1097 C C   . GLN B 1 17  ? 249.764 325.477 402.966 1.00 111.96 ? 17  GLN B C   1 
ATOM 1098 O O   . GLN B 1 17  ? 249.476 324.278 402.924 1.00 111.96 ? 17  GLN B O   1 
ATOM 1099 C CB  . GLN B 1 17  ? 252.146 325.851 402.314 1.00 111.96 ? 17  GLN B CB  1 
ATOM 1100 C CG  . GLN B 1 17  ? 253.502 326.447 402.639 1.00 111.96 ? 17  GLN B CG  1 
ATOM 1101 C CD  . GLN B 1 17  ? 254.444 326.418 401.454 1.00 111.96 ? 17  GLN B CD  1 
ATOM 1102 O OE1 . GLN B 1 17  ? 254.011 326.404 400.302 1.00 111.96 ? 17  GLN B OE1 1 
ATOM 1103 N NE2 . GLN B 1 17  ? 255.742 326.407 401.730 1.00 111.96 ? 17  GLN B NE2 1 
ATOM 1104 N N   . THR B 1 18  ? 248.916 326.435 402.606 1.00 102.06 ? 18  THR B N   1 
ATOM 1105 C CA  . THR B 1 18  ? 247.602 326.154 402.052 1.00 102.06 ? 18  THR B CA  1 
ATOM 1106 C C   . THR B 1 18  ? 247.512 326.687 400.629 1.00 102.06 ? 18  THR B C   1 
ATOM 1107 O O   . THR B 1 18  ? 248.232 327.609 400.237 1.00 102.06 ? 18  THR B O   1 
ATOM 1108 C CB  . THR B 1 18  ? 246.492 326.771 402.909 1.00 102.06 ? 18  THR B CB  1 
ATOM 1109 O OG1 . THR B 1 18  ? 246.566 328.200 402.833 1.00 102.06 ? 18  THR B OG1 1 
ATOM 1110 C CG2 . THR B 1 18  ? 246.635 326.338 404.359 1.00 102.06 ? 18  THR B CG2 1 
ATOM 1111 N N   . LEU B 1 19  ? 246.610 326.091 399.854 1.00 88.81  ? 19  LEU B N   1 
ATOM 1112 C CA  . LEU B 1 19  ? 246.445 326.457 398.455 1.00 88.81  ? 19  LEU B CA  1 
ATOM 1113 C C   . LEU B 1 19  ? 244.963 326.528 398.127 1.00 88.81  ? 19  LEU B C   1 
ATOM 1114 O O   . LEU B 1 19  ? 244.205 325.620 398.479 1.00 88.81  ? 19  LEU B O   1 
ATOM 1115 C CB  . LEU B 1 19  ? 247.142 325.448 397.538 1.00 88.81  ? 19  LEU B CB  1 
ATOM 1116 C CG  . LEU B 1 19  ? 246.938 325.656 396.038 1.00 88.81  ? 19  LEU B CG  1 
ATOM 1117 C CD1 . LEU B 1 19  ? 247.475 327.011 395.618 1.00 88.81  ? 19  LEU B CD1 1 
ATOM 1118 C CD2 . LEU B 1 19  ? 247.598 324.543 395.242 1.00 88.81  ? 19  LEU B CD2 1 
ATOM 1119 N N   . VAL B 1 20  ? 244.559 327.604 397.458 1.00 87.07  ? 20  VAL B N   1 
ATOM 1120 C CA  . VAL B 1 20  ? 243.196 327.759 396.969 1.00 87.07  ? 20  VAL B CA  1 
ATOM 1121 C C   . VAL B 1 20  ? 243.229 327.714 395.451 1.00 87.07  ? 20  VAL B C   1 
ATOM 1122 O O   . VAL B 1 20  ? 244.239 328.045 394.820 1.00 87.07  ? 20  VAL B O   1 
ATOM 1123 C CB  . VAL B 1 20  ? 242.541 329.066 397.461 1.00 87.07  ? 20  VAL B CB  1 
ATOM 1124 C CG1 . VAL B 1 20  ? 242.257 328.988 398.949 1.00 87.07  ? 20  VAL B CG1 1 
ATOM 1125 C CG2 . VAL B 1 20  ? 243.428 330.254 397.143 1.00 87.07  ? 20  VAL B CG2 1 
ATOM 1126 N N   . LEU B 1 21  ? 242.113 327.297 394.861 1.00 80.01  ? 21  LEU B N   1 
ATOM 1127 C CA  . LEU B 1 21  ? 242.002 327.192 393.415 1.00 80.01  ? 21  LEU B CA  1 
ATOM 1128 C C   . LEU B 1 21  ? 240.639 327.707 392.982 1.00 80.01  ? 21  LEU B C   1 
ATOM 1129 O O   . LEU B 1 21  ? 239.703 327.794 393.779 1.00 80.01  ? 21  LEU B O   1 
ATOM 1130 C CB  . LEU B 1 21  ? 242.202 325.750 392.935 1.00 80.01  ? 21  LEU B CB  1 
ATOM 1131 C CG  . LEU B 1 21  ? 243.600 325.168 393.136 1.00 80.01  ? 21  LEU B CG  1 
ATOM 1132 C CD1 . LEU B 1 21  ? 243.643 323.718 392.697 1.00 80.01  ? 21  LEU B CD1 1 
ATOM 1133 C CD2 . LEU B 1 21  ? 244.625 325.985 392.375 1.00 80.01  ? 21  LEU B CD2 1 
ATOM 1134 N N   . ASN B 1 22  ? 240.540 328.057 391.705 1.00 76.77  ? 22  ASN B N   1 
ATOM 1135 C CA  . ASN B 1 22  ? 239.294 328.540 391.139 1.00 76.77  ? 22  ASN B CA  1 
ATOM 1136 C C   . ASN B 1 22  ? 239.016 327.840 389.820 1.00 76.77  ? 22  ASN B C   1 
ATOM 1137 O O   . ASN B 1 22  ? 239.947 327.488 389.089 1.00 76.77  ? 22  ASN B O   1 
ATOM 1138 C CB  . ASN B 1 22  ? 239.342 330.056 390.914 1.00 76.77  ? 22  ASN B CB  1 
ATOM 1139 C CG  . ASN B 1 22  ? 239.776 330.810 392.149 1.00 76.77  ? 22  ASN B CG  1 
ATOM 1140 O OD1 . ASN B 1 22  ? 240.761 331.546 392.126 1.00 76.77  ? 22  ASN B OD1 1 
ATOM 1141 N ND2 . ASN B 1 22  ? 239.046 330.624 393.240 1.00 76.77  ? 22  ASN B ND2 1 
ATOM 1142 N N   . PRO B 1 23  ? 237.747 327.617 389.494 1.00 76.66  ? 23  PRO B N   1 
ATOM 1143 C CA  . PRO B 1 23  ? 237.417 327.033 388.193 1.00 76.66  ? 23  PRO B CA  1 
ATOM 1144 C C   . PRO B 1 23  ? 237.763 327.987 387.065 1.00 76.66  ? 23  PRO B C   1 
ATOM 1145 O O   . PRO B 1 23  ? 237.720 329.209 387.218 1.00 76.66  ? 23  PRO B O   1 
ATOM 1146 C CB  . PRO B 1 23  ? 235.906 326.802 388.280 1.00 76.66  ? 23  PRO B CB  1 
ATOM 1147 C CG  . PRO B 1 23  ? 235.440 327.792 389.289 1.00 76.66  ? 23  PRO B CG  1 
ATOM 1148 C CD  . PRO B 1 23  ? 236.545 327.893 390.297 1.00 76.66  ? 23  PRO B CD  1 
ATOM 1149 N N   . ARG B 1 24  ? 238.118 327.412 385.920 1.00 74.40  ? 24  ARG B N   1 
ATOM 1150 C CA  . ARG B 1 24  ? 238.469 328.201 384.747 1.00 74.40  ? 24  ARG B CA  1 
ATOM 1151 C C   . ARG B 1 24  ? 237.857 327.592 383.497 1.00 74.40  ? 24  ARG B C   1 
ATOM 1152 O O   . ARG B 1 24  ? 238.508 327.480 382.454 1.00 74.40  ? 24  ARG B O   1 
ATOM 1153 C CB  . ARG B 1 24  ? 239.983 328.333 384.603 1.00 74.40  ? 24  ARG B CB  1 
ATOM 1154 C CG  . ARG B 1 24  ? 240.592 329.359 385.540 1.00 74.40  ? 24  ARG B CG  1 
ATOM 1155 C CD  . ARG B 1 24  ? 240.818 330.676 384.832 1.00 74.40  ? 24  ARG B CD  1 
ATOM 1156 N NE  . ARG B 1 24  ? 241.353 330.476 383.491 1.00 74.40  ? 24  ARG B NE  1 
ATOM 1157 C CZ  . ARG B 1 24  ? 242.630 330.621 383.167 1.00 74.40  ? 24  ARG B CZ  1 
ATOM 1158 N NH1 . ARG B 1 24  ? 243.534 330.977 384.065 1.00 74.40  ? 24  ARG B NH1 1 
ATOM 1159 N NH2 . ARG B 1 24  ? 243.009 330.405 381.911 1.00 74.40  ? 24  ARG B NH2 1 
ATOM 1160 N N   . GLY B 1 25  ? 236.598 327.178 383.590 1.00 71.33  ? 25  GLY B N   1 
ATOM 1161 C CA  . GLY B 1 25  ? 235.884 326.680 382.433 1.00 71.33  ? 25  GLY B CA  1 
ATOM 1162 C C   . GLY B 1 25  ? 236.330 325.303 381.996 1.00 71.33  ? 25  GLY B C   1 
ATOM 1163 O O   . GLY B 1 25  ? 237.306 324.762 382.522 1.00 71.33  ? 25  GLY B O   1 
ATOM 1164 N N   . VAL B 1 26  ? 235.622 324.727 381.029 1.00 73.74  ? 26  VAL B N   1 
ATOM 1165 C CA  . VAL B 1 26  ? 235.933 323.409 380.494 1.00 73.74  ? 26  VAL B CA  1 
ATOM 1166 C C   . VAL B 1 26  ? 236.093 323.539 378.989 1.00 73.74  ? 26  VAL B C   1 
ATOM 1167 O O   . VAL B 1 26  ? 235.175 324.000 378.300 1.00 73.74  ? 26  VAL B O   1 
ATOM 1168 C CB  . VAL B 1 26  ? 234.845 322.381 380.835 1.00 73.74  ? 26  VAL B CB  1 
ATOM 1169 C CG1 . VAL B 1 26  ? 235.215 321.021 380.273 1.00 73.74  ? 26  VAL B CG1 1 
ATOM 1170 C CG2 . VAL B 1 26  ? 234.638 322.306 382.333 1.00 73.74  ? 26  VAL B CG2 1 
ATOM 1171 N N   . ASN B 1 27  ? 237.245 323.134 378.481 1.00 77.64  ? 27  ASN B N   1 
ATOM 1172 C CA  . ASN B 1 27  ? 237.460 323.122 377.042 1.00 77.64  ? 27  ASN B CA  1 
ATOM 1173 C C   . ASN B 1 27  ? 236.621 322.012 376.424 1.00 77.64  ? 27  ASN B C   1 
ATOM 1174 O O   . ASN B 1 27  ? 236.797 320.842 376.786 1.00 77.64  ? 27  ASN B O   1 
ATOM 1175 C CB  . ASN B 1 27  ? 238.939 322.916 376.733 1.00 77.64  ? 27  ASN B CB  1 
ATOM 1176 C CG  . ASN B 1 27  ? 239.262 323.095 375.263 1.00 77.64  ? 27  ASN B CG  1 
ATOM 1177 O OD1 . ASN B 1 27  ? 238.380 323.351 374.445 1.00 77.64  ? 27  ASN B OD1 1 
ATOM 1178 N ND2 . ASN B 1 27  ? 240.537 322.961 374.921 1.00 77.64  ? 27  ASN B ND2 1 
ATOM 1179 N N   . PRO B 1 28  ? 235.704 322.320 375.504 1.00 72.81  ? 28  PRO B N   1 
ATOM 1180 C CA  . PRO B 1 28  ? 234.872 321.264 374.913 1.00 72.81  ? 28  PRO B CA  1 
ATOM 1181 C C   . PRO B 1 28  ? 235.536 320.514 373.774 1.00 72.81  ? 28  PRO B C   1 
ATOM 1182 O O   . PRO B 1 28  ? 234.980 319.506 373.320 1.00 72.81  ? 28  PRO B O   1 
ATOM 1183 C CB  . PRO B 1 28  ? 233.647 322.036 374.416 1.00 72.81  ? 28  PRO B CB  1 
ATOM 1184 C CG  . PRO B 1 28  ? 234.191 323.372 374.066 1.00 72.81  ? 28  PRO B CG  1 
ATOM 1185 C CD  . PRO B 1 28  ? 235.288 323.660 375.060 1.00 72.81  ? 28  PRO B CD  1 
ATOM 1186 N N   . THR B 1 29  ? 236.697 320.964 373.297 1.00 72.52  ? 29  THR B N   1 
ATOM 1187 C CA  . THR B 1 29  ? 237.343 320.293 372.175 1.00 72.52  ? 29  THR B CA  1 
ATOM 1188 C C   . THR B 1 29  ? 237.825 318.902 372.570 1.00 72.52  ? 29  THR B C   1 
ATOM 1189 O O   . THR B 1 29  ? 237.392 317.895 371.999 1.00 72.52  ? 29  THR B O   1 
ATOM 1190 C CB  . THR B 1 29  ? 238.508 321.136 371.657 1.00 72.52  ? 29  THR B CB  1 
ATOM 1191 O OG1 . THR B 1 29  ? 239.423 321.393 372.728 1.00 72.52  ? 29  THR B OG1 1 
ATOM 1192 C CG2 . THR B 1 29  ? 238.001 322.453 371.105 1.00 72.52  ? 29  THR B CG2 1 
ATOM 1193 N N   . ASN B 1 30  ? 238.723 318.827 373.549 1.00 72.36  ? 30  ASN B N   1 
ATOM 1194 C CA  . ASN B 1 30  ? 239.280 317.561 374.001 1.00 72.36  ? 30  ASN B CA  1 
ATOM 1195 C C   . ASN B 1 30  ? 238.646 317.065 375.294 1.00 72.36  ? 30  ASN B C   1 
ATOM 1196 O O   . ASN B 1 30  ? 239.148 316.106 375.887 1.00 72.36  ? 30  ASN B O   1 
ATOM 1197 C CB  . ASN B 1 30  ? 240.794 317.686 374.172 1.00 72.36  ? 30  ASN B CB  1 
ATOM 1198 C CG  . ASN B 1 30  ? 241.186 318.857 375.044 1.00 72.36  ? 30  ASN B CG  1 
ATOM 1199 O OD1 . ASN B 1 30  ? 240.337 319.501 375.658 1.00 72.36  ? 30  ASN B OD1 1 
ATOM 1200 N ND2 . ASN B 1 30  ? 242.480 319.145 375.100 1.00 72.36  ? 30  ASN B ND2 1 
ATOM 1201 N N   . GLY B 1 31  ? 237.562 317.693 375.742 1.00 73.26  ? 31  GLY B N   1 
ATOM 1202 C CA  . GLY B 1 31  ? 236.874 317.259 376.942 1.00 73.26  ? 31  GLY B CA  1 
ATOM 1203 C C   . GLY B 1 31  ? 237.729 317.341 378.187 1.00 73.26  ? 31  GLY B C   1 
ATOM 1204 O O   . GLY B 1 31  ? 237.763 316.402 378.986 1.00 73.26  ? 31  GLY B O   1 
ATOM 1205 N N   . VAL B 1 32  ? 238.423 318.461 378.367 1.00 71.58  ? 32  VAL B N   1 
ATOM 1206 C CA  . VAL B 1 32  ? 239.369 318.640 379.459 1.00 71.58  ? 32  VAL B CA  1 
ATOM 1207 C C   . VAL B 1 32  ? 238.899 319.793 380.331 1.00 71.58  ? 32  VAL B C   1 
ATOM 1208 O O   . VAL B 1 32  ? 238.619 320.886 379.826 1.00 71.58  ? 32  VAL B O   1 
ATOM 1209 C CB  . VAL B 1 32  ? 240.791 318.905 378.933 1.00 71.58  ? 32  VAL B CB  1 
ATOM 1210 C CG1 . VAL B 1 32  ? 241.685 319.410 380.050 1.00 71.58  ? 32  VAL B CG1 1 
ATOM 1211 C CG2 . VAL B 1 32  ? 241.364 317.647 378.310 1.00 71.58  ? 32  VAL B CG2 1 
ATOM 1212 N N   . ALA B 1 33  ? 238.811 319.549 381.633 1.00 67.80  ? 33  ALA B N   1 
ATOM 1213 C CA  . ALA B 1 33  ? 238.541 320.602 382.599 1.00 67.80  ? 33  ALA B CA  1 
ATOM 1214 C C   . ALA B 1 33  ? 239.854 321.198 383.087 1.00 67.80  ? 33  ALA B C   1 
ATOM 1215 O O   . ALA B 1 33  ? 240.898 320.543 383.070 1.00 67.80  ? 33  ALA B O   1 
ATOM 1216 C CB  . ALA B 1 33  ? 237.736 320.066 383.781 1.00 67.80  ? 33  ALA B CB  1 
ATOM 1217 N N   . SER B 1 34  ? 239.796 322.454 383.518 1.00 72.60  ? 34  SER B N   1 
ATOM 1218 C CA  . SER B 1 34  ? 240.986 323.179 383.936 1.00 72.60  ? 34  SER B CA  1 
ATOM 1219 C C   . SER B 1 34  ? 240.722 323.926 385.232 1.00 72.60  ? 34  SER B C   1 
ATOM 1220 O O   . SER B 1 34  ? 239.601 324.375 385.485 1.00 72.60  ? 34  SER B O   1 
ATOM 1221 C CB  . SER B 1 34  ? 241.443 324.165 382.856 1.00 72.60  ? 34  SER B CB  1 
ATOM 1222 O OG  . SER B 1 34  ? 241.806 323.487 381.666 1.00 72.60  ? 34  SER B OG  1 
ATOM 1223 N N   . LEU B 1 35  ? 241.761 324.052 386.049 1.00 72.06  ? 35  LEU B N   1 
ATOM 1224 C CA  . LEU B 1 35  ? 241.743 324.868 387.252 1.00 72.06  ? 35  LEU B CA  1 
ATOM 1225 C C   . LEU B 1 35  ? 242.925 325.826 387.221 1.00 72.06  ? 35  LEU B C   1 
ATOM 1226 O O   . LEU B 1 35  ? 243.789 325.755 386.344 1.00 72.06  ? 35  LEU B O   1 
ATOM 1227 C CB  . LEU B 1 35  ? 241.789 324.002 388.515 1.00 72.06  ? 35  LEU B CB  1 
ATOM 1228 C CG  . LEU B 1 35  ? 240.450 323.546 389.091 1.00 72.06  ? 35  LEU B CG  1 
ATOM 1229 C CD1 . LEU B 1 35  ? 239.804 322.496 388.206 1.00 72.06  ? 35  LEU B CD1 1 
ATOM 1230 C CD2 . LEU B 1 35  ? 240.640 323.016 390.501 1.00 72.06  ? 35  LEU B CD2 1 
ATOM 1231 N N   . SER B 1 36  ? 242.962 326.732 388.194 1.00 79.60  ? 36  SER B N   1 
ATOM 1232 C CA  . SER B 1 36  ? 244.042 327.705 388.272 1.00 79.60  ? 36  SER B CA  1 
ATOM 1233 C C   . SER B 1 36  ? 244.058 328.322 389.661 1.00 79.60  ? 36  SER B C   1 
ATOM 1234 O O   . SER B 1 36  ? 243.120 328.166 390.445 1.00 79.60  ? 36  SER B O   1 
ATOM 1235 C CB  . SER B 1 36  ? 243.898 328.790 387.204 1.00 79.60  ? 36  SER B CB  1 
ATOM 1236 O OG  . SER B 1 36  ? 244.760 329.880 387.478 1.00 79.60  ? 36  SER B OG  1 
ATOM 1237 N N   . GLN B 1 37  ? 245.146 329.026 389.953 1.00 82.19  ? 37  GLN B N   1 
ATOM 1238 C CA  . GLN B 1 37  ? 245.261 329.811 391.169 1.00 82.19  ? 37  GLN B CA  1 
ATOM 1239 C C   . GLN B 1 37  ? 244.748 331.228 390.917 1.00 82.19  ? 37  GLN B C   1 
ATOM 1240 O O   . GLN B 1 37  ? 244.364 331.589 389.804 1.00 82.19  ? 37  GLN B O   1 
ATOM 1241 C CB  . GLN B 1 37  ? 246.710 329.828 391.658 1.00 82.19  ? 37  GLN B CB  1 
ATOM 1242 C CG  . GLN B 1 37  ? 246.867 330.036 393.154 1.00 82.19  ? 37  GLN B CG  1 
ATOM 1243 C CD  . GLN B 1 37  ? 248.317 330.080 393.584 1.00 82.19  ? 37  GLN B CD  1 
ATOM 1244 O OE1 . GLN B 1 37  ? 249.223 330.054 392.752 1.00 82.19  ? 37  GLN B OE1 1 
ATOM 1245 N NE2 . GLN B 1 37  ? 248.545 330.152 394.889 1.00 82.19  ? 37  GLN B NE2 1 
ATOM 1246 N N   . ALA B 1 38  ? 244.749 332.040 391.971 1.00 82.43  ? 38  ALA B N   1 
ATOM 1247 C CA  . ALA B 1 38  ? 244.163 333.372 391.907 1.00 82.43  ? 38  ALA B CA  1 
ATOM 1248 C C   . ALA B 1 38  ? 245.114 334.432 391.365 1.00 82.43  ? 38  ALA B C   1 
ATOM 1249 O O   . ALA B 1 38  ? 244.708 335.592 391.242 1.00 82.43  ? 38  ALA B O   1 
ATOM 1250 C CB  . ALA B 1 38  ? 243.666 333.791 393.293 1.00 82.43  ? 38  ALA B CB  1 
ATOM 1251 N N   . GLY B 1 39  ? 246.357 334.077 391.047 1.00 82.26  ? 39  GLY B N   1 
ATOM 1252 C CA  . GLY B 1 39  ? 247.285 335.072 390.536 1.00 82.26  ? 39  GLY B CA  1 
ATOM 1253 C C   . GLY B 1 39  ? 246.828 335.619 389.196 1.00 82.26  ? 39  GLY B C   1 
ATOM 1254 O O   . GLY B 1 39  ? 246.256 334.903 388.371 1.00 82.26  ? 39  GLY B O   1 
ATOM 1255 N N   . ALA B 1 40  ? 247.077 336.908 388.984 1.00 84.29  ? 40  ALA B N   1 
ATOM 1256 C CA  . ALA B 1 40  ? 246.640 337.596 387.769 1.00 84.29  ? 40  ALA B CA  1 
ATOM 1257 C C   . ALA B 1 40  ? 247.733 337.637 386.704 1.00 84.29  ? 40  ALA B C   1 
ATOM 1258 O O   . ALA B 1 40  ? 248.058 338.694 386.167 1.00 84.29  ? 40  ALA B O   1 
ATOM 1259 C CB  . ALA B 1 40  ? 246.167 339.002 388.117 1.00 84.29  ? 40  ALA B CB  1 
ATOM 1260 N N   . VAL B 1 41  ? 248.304 336.481 386.382 1.00 76.24  ? 41  VAL B N   1 
ATOM 1261 C CA  . VAL B 1 41  ? 249.282 336.367 385.302 1.00 76.24  ? 41  VAL B CA  1 
ATOM 1262 C C   . VAL B 1 41  ? 249.018 335.065 384.555 1.00 76.24  ? 41  VAL B C   1 
ATOM 1263 O O   . VAL B 1 41  ? 248.998 333.992 385.172 1.00 76.24  ? 41  VAL B O   1 
ATOM 1264 C CB  . VAL B 1 41  ? 250.725 336.413 385.827 1.00 76.24  ? 41  VAL B CB  1 
ATOM 1265 C CG1 . VAL B 1 41  ? 251.691 336.073 384.711 1.00 76.24  ? 41  VAL B CG1 1 
ATOM 1266 C CG2 . VAL B 1 41  ? 251.051 337.782 386.402 1.00 76.24  ? 41  VAL B CG2 1 
ATOM 1267 N N   . PRO B 1 42  ? 248.817 335.106 383.236 1.00 71.22  ? 42  PRO B N   1 
ATOM 1268 C CA  . PRO B 1 42  ? 248.430 333.887 382.508 1.00 71.22  ? 42  PRO B CA  1 
ATOM 1269 C C   . PRO B 1 42  ? 249.489 332.797 382.484 1.00 71.22  ? 42  PRO B C   1 
ATOM 1270 O O   . PRO B 1 42  ? 249.142 331.645 382.195 1.00 71.22  ? 42  PRO B O   1 
ATOM 1271 C CB  . PRO B 1 42  ? 248.146 334.403 381.092 1.00 71.22  ? 42  PRO B CB  1 
ATOM 1272 C CG  . PRO B 1 42  ? 247.885 335.863 381.265 1.00 71.22  ? 42  PRO B CG  1 
ATOM 1273 C CD  . PRO B 1 42  ? 248.789 336.293 382.373 1.00 71.22  ? 42  PRO B CD  1 
ATOM 1274 N N   . ALA B 1 43  ? 250.756 333.101 382.767 1.00 72.81  ? 43  ALA B N   1 
ATOM 1275 C CA  . ALA B 1 43  ? 251.822 332.113 382.631 1.00 72.81  ? 43  ALA B CA  1 
ATOM 1276 C C   . ALA B 1 43  ? 252.589 331.886 383.928 1.00 72.81  ? 43  ALA B C   1 
ATOM 1277 O O   . ALA B 1 43  ? 253.698 331.346 383.897 1.00 72.81  ? 43  ALA B O   1 
ATOM 1278 C CB  . ALA B 1 43  ? 252.785 332.518 381.514 1.00 72.81  ? 43  ALA B CB  1 
ATOM 1279 N N   . LEU B 1 44  ? 252.027 332.278 385.066 1.00 79.32  ? 44  LEU B N   1 
ATOM 1280 C CA  . LEU B 1 44  ? 252.640 332.055 386.370 1.00 79.32  ? 44  LEU B CA  1 
ATOM 1281 C C   . LEU B 1 44  ? 251.632 331.462 387.339 1.00 79.32  ? 44  LEU B C   1 
ATOM 1282 O O   . LEU B 1 44  ? 251.646 331.755 388.538 1.00 79.32  ? 44  LEU B O   1 
ATOM 1283 C CB  . LEU B 1 44  ? 253.220 333.348 386.936 1.00 79.32  ? 44  LEU B CB  1 
ATOM 1284 C CG  . LEU B 1 44  ? 254.330 334.027 386.140 1.00 79.32  ? 44  LEU B CG  1 
ATOM 1285 C CD1 . LEU B 1 44  ? 254.807 335.268 386.870 1.00 79.32  ? 44  LEU B CD1 1 
ATOM 1286 C CD2 . LEU B 1 44  ? 255.480 333.068 385.913 1.00 79.32  ? 44  LEU B CD2 1 
ATOM 1287 N N   . GLU B 1 45  ? 250.743 330.611 386.838 1.00 83.36  ? 45  GLU B N   1 
ATOM 1288 C CA  . GLU B 1 45  ? 249.629 330.090 387.616 1.00 83.36  ? 45  GLU B CA  1 
ATOM 1289 C C   . GLU B 1 45  ? 249.739 328.580 387.742 1.00 83.36  ? 45  GLU B C   1 
ATOM 1290 O O   . GLU B 1 45  ? 249.973 327.886 386.748 1.00 83.36  ? 45  GLU B O   1 
ATOM 1291 C CB  . GLU B 1 45  ? 248.293 330.460 386.969 1.00 83.36  ? 45  GLU B CB  1 
ATOM 1292 C CG  . GLU B 1 45  ? 247.856 331.890 387.210 1.00 83.36  ? 45  GLU B CG  1 
ATOM 1293 C CD  . GLU B 1 45  ? 248.108 332.350 388.629 1.00 83.36  ? 45  GLU B CD  1 
ATOM 1294 O OE1 . GLU B 1 45  ? 247.256 332.078 389.498 1.00 83.36  ? 45  GLU B OE1 1 
ATOM 1295 O OE2 . GLU B 1 45  ? 249.150 332.993 388.876 1.00 83.36  ? 45  GLU B OE2 1 
ATOM 1296 N N   . LYS B 1 46  ? 249.571 328.078 388.964 1.00 76.52  ? 46  LYS B N   1 
ATOM 1297 C CA  . LYS B 1 46  ? 249.413 326.646 389.163 1.00 76.52  ? 46  LYS B CA  1 
ATOM 1298 C C   . LYS B 1 46  ? 248.183 326.168 388.407 1.00 76.52  ? 46  LYS B C   1 
ATOM 1299 O O   . LYS B 1 46  ? 247.113 326.776 388.497 1.00 76.52  ? 46  LYS B O   1 
ATOM 1300 C CB  . LYS B 1 46  ? 249.273 326.332 390.650 1.00 76.52  ? 46  LYS B CB  1 
ATOM 1301 C CG  . LYS B 1 46  ? 250.138 327.182 391.563 1.00 76.52  ? 46  LYS B CG  1 
ATOM 1302 C CD  . LYS B 1 46  ? 251.604 326.819 391.449 1.00 76.52  ? 46  LYS B CD  1 
ATOM 1303 C CE  . LYS B 1 46  ? 252.318 327.030 392.775 1.00 76.52  ? 46  LYS B CE  1 
ATOM 1304 N NZ  . LYS B 1 46  ? 253.734 326.571 392.732 1.00 76.52  ? 46  LYS B NZ  1 
ATOM 1305 N N   . ARG B 1 47  ? 248.328 325.080 387.659 1.00 69.72  ? 47  ARG B N   1 
ATOM 1306 C CA  . ARG B 1 47  ? 247.255 324.593 386.805 1.00 69.72  ? 47  ARG B CA  1 
ATOM 1307 C C   . ARG B 1 47  ? 246.969 323.133 387.111 1.00 69.72  ? 47  ARG B C   1 
ATOM 1308 O O   . ARG B 1 47  ? 247.893 322.317 387.186 1.00 69.72  ? 47  ARG B O   1 
ATOM 1309 C CB  . ARG B 1 47  ? 247.606 324.766 385.327 1.00 69.72  ? 47  ARG B CB  1 
ATOM 1310 C CG  . ARG B 1 47  ? 247.403 326.179 384.818 1.00 69.72  ? 47  ARG B CG  1 
ATOM 1311 C CD  . ARG B 1 47  ? 247.503 326.238 383.309 1.00 69.72  ? 47  ARG B CD  1 
ATOM 1312 N NE  . ARG B 1 47  ? 247.046 327.519 382.785 1.00 69.72  ? 47  ARG B NE  1 
ATOM 1313 C CZ  . ARG B 1 47  ? 247.108 327.870 381.509 1.00 69.72  ? 47  ARG B CZ  1 
ATOM 1314 N NH1 . ARG B 1 47  ? 247.614 327.060 380.593 1.00 69.72  ? 47  ARG B NH1 1 
ATOM 1315 N NH2 . ARG B 1 47  ? 246.651 329.064 381.141 1.00 69.72  ? 47  ARG B NH2 1 
ATOM 1316 N N   . VAL B 1 48  ? 245.692 322.810 387.287 1.00 64.24  ? 48  VAL B N   1 
ATOM 1317 C CA  . VAL B 1 48  ? 245.232 321.445 387.503 1.00 64.24  ? 48  VAL B CA  1 
ATOM 1318 C C   . VAL B 1 48  ? 244.229 321.113 386.411 1.00 64.24  ? 48  VAL B C   1 
ATOM 1319 O O   . VAL B 1 48  ? 243.254 321.846 386.216 1.00 64.24  ? 48  VAL B O   1 
ATOM 1320 C CB  . VAL B 1 48  ? 244.591 321.270 388.890 1.00 64.24  ? 48  VAL B CB  1 
ATOM 1321 C CG1 . VAL B 1 48  ? 244.437 319.801 389.211 1.00 64.24  ? 48  VAL B CG1 1 
ATOM 1322 C CG2 . VAL B 1 48  ? 245.406 321.982 389.953 1.00 64.24  ? 48  VAL B CG2 1 
ATOM 1323 N N   . THR B 1 49  ? 244.466 320.014 385.701 1.00 62.68  ? 49  THR B N   1 
ATOM 1324 C CA  . THR B 1 49  ? 243.581 319.583 384.628 1.00 62.68  ? 49  THR B CA  1 
ATOM 1325 C C   . THR B 1 49  ? 243.140 318.152 384.885 1.00 62.68  ? 49  THR B C   1 
ATOM 1326 O O   . THR B 1 49  ? 243.972 317.286 385.171 1.00 62.68  ? 49  THR B O   1 
ATOM 1327 C CB  . THR B 1 49  ? 244.266 319.677 383.261 1.00 62.68  ? 49  THR B CB  1 
ATOM 1328 O OG1 . THR B 1 49  ? 245.161 318.572 383.098 1.00 62.68  ? 49  THR B OG1 1 
ATOM 1329 C CG2 . THR B 1 49  ? 245.051 320.971 383.143 1.00 62.68  ? 49  THR B CG2 1 
ATOM 1330 N N   . VAL B 1 50  ? 241.837 317.906 384.782 1.00 59.68  ? 50  VAL B N   1 
ATOM 1331 C CA  . VAL B 1 50  ? 241.279 316.567 384.899 1.00 59.68  ? 50  VAL B CA  1 
ATOM 1332 C C   . VAL B 1 50  ? 240.422 316.304 383.672 1.00 59.68  ? 50  VAL B C   1 
ATOM 1333 O O   . VAL B 1 50  ? 239.895 317.232 383.051 1.00 59.68  ? 50  VAL B O   1 
ATOM 1334 C CB  . VAL B 1 50  ? 240.451 316.385 386.188 1.00 59.68  ? 50  VAL B CB  1 
ATOM 1335 C CG1 . VAL B 1 50  ? 241.323 316.584 387.411 1.00 59.68  ? 50  VAL B CG1 1 
ATOM 1336 C CG2 . VAL B 1 50  ? 239.278 317.342 386.205 1.00 59.68  ? 50  VAL B CG2 1 
ATOM 1337 N N   . SER B 1 51  ? 240.283 315.029 383.322 1.00 62.45  ? 51  SER B N   1 
ATOM 1338 C CA  . SER B 1 51  ? 239.528 314.653 382.135 1.00 62.45  ? 51  SER B CA  1 
ATOM 1339 C C   . SER B 1 51  ? 239.247 313.161 382.181 1.00 62.45  ? 51  SER B C   1 
ATOM 1340 O O   . SER B 1 51  ? 239.847 312.422 382.965 1.00 62.45  ? 51  SER B O   1 
ATOM 1341 C CB  . SER B 1 51  ? 240.283 315.005 380.851 1.00 62.45  ? 51  SER B CB  1 
ATOM 1342 O OG  . SER B 1 51  ? 241.415 314.171 380.687 1.00 62.45  ? 51  SER B OG  1 
ATOM 1343 N N   . VAL B 1 52  ? 238.322 312.731 381.328 1.00 62.43  ? 52  VAL B N   1 
ATOM 1344 C CA  . VAL B 1 52  ? 238.062 311.313 381.117 1.00 62.43  ? 52  VAL B CA  1 
ATOM 1345 C C   . VAL B 1 52  ? 238.231 311.035 379.633 1.00 62.43  ? 52  VAL B C   1 
ATOM 1346 O O   . VAL B 1 52  ? 238.577 311.933 378.858 1.00 62.43  ? 52  VAL B O   1 
ATOM 1347 C CB  . VAL B 1 52  ? 236.659 310.905 381.594 1.00 62.43  ? 52  VAL B CB  1 
ATOM 1348 C CG1 . VAL B 1 52  ? 236.442 311.320 383.038 1.00 62.43  ? 52  VAL B CG1 1 
ATOM 1349 C CG2 . VAL B 1 52  ? 235.607 311.493 380.684 1.00 62.43  ? 52  VAL B CG2 1 
ATOM 1350 N N   . SER B 1 53  ? 237.997 309.793 379.225 1.00 70.88  ? 53  SER B N   1 
ATOM 1351 C CA  . SER B 1 53  ? 238.035 309.444 377.809 1.00 70.88  ? 53  SER B CA  1 
ATOM 1352 C C   . SER B 1 53  ? 237.077 308.285 377.588 1.00 70.88  ? 53  SER B C   1 
ATOM 1353 O O   . SER B 1 53  ? 237.392 307.146 377.943 1.00 70.88  ? 53  SER B O   1 
ATOM 1354 C CB  . SER B 1 53  ? 239.448 309.081 377.367 1.00 70.88  ? 53  SER B CB  1 
ATOM 1355 O OG  . SER B 1 53  ? 239.476 308.765 375.987 1.00 70.88  ? 53  SER B OG  1 
ATOM 1356 N N   . GLN B 1 54  ? 235.915 308.576 377.012 1.00 80.40  ? 54  GLN B N   1 
ATOM 1357 C CA  . GLN B 1 54  ? 234.964 307.524 376.708 1.00 80.40  ? 54  GLN B CA  1 
ATOM 1358 C C   . GLN B 1 54  ? 235.566 306.571 375.676 1.00 80.40  ? 54  GLN B C   1 
ATOM 1359 O O   . GLN B 1 54  ? 236.324 306.993 374.798 1.00 80.40  ? 54  GLN B O   1 
ATOM 1360 C CB  . GLN B 1 54  ? 233.657 308.119 376.185 1.00 80.40  ? 54  GLN B CB  1 
ATOM 1361 C CG  . GLN B 1 54  ? 232.909 309.006 377.181 1.00 80.40  ? 54  GLN B CG  1 
ATOM 1362 C CD  . GLN B 1 54  ? 232.291 308.246 378.348 1.00 80.40  ? 54  GLN B CD  1 
ATOM 1363 O OE1 . GLN B 1 54  ? 232.784 307.200 378.768 1.00 80.40  ? 54  GLN B OE1 1 
ATOM 1364 N NE2 . GLN B 1 54  ? 231.199 308.783 378.881 1.00 80.40  ? 54  GLN B NE2 1 
ATOM 1365 N N   . PRO B 1 55  ? 235.262 305.279 375.769 1.00 78.41  ? 55  PRO B N   1 
ATOM 1366 C CA  . PRO B 1 55  ? 235.878 304.316 374.853 1.00 78.41  ? 55  PRO B CA  1 
ATOM 1367 C C   . PRO B 1 55  ? 235.439 304.556 373.418 1.00 78.41  ? 55  PRO B C   1 
ATOM 1368 O O   . PRO B 1 55  ? 234.261 304.788 373.137 1.00 78.41  ? 55  PRO B O   1 
ATOM 1369 C CB  . PRO B 1 55  ? 235.380 302.965 375.375 1.00 78.41  ? 55  PRO B CB  1 
ATOM 1370 C CG  . PRO B 1 55  ? 234.101 303.287 376.063 1.00 78.41  ? 55  PRO B CG  1 
ATOM 1371 C CD  . PRO B 1 55  ? 234.301 304.639 376.680 1.00 78.41  ? 55  PRO B CD  1 
ATOM 1372 N N   . SER B 1 56  ? 236.402 304.498 372.510 1.00 92.71  ? 56  SER B N   1 
ATOM 1373 C CA  . SER B 1 56  ? 236.157 304.649 371.089 1.00 92.71  ? 56  SER B CA  1 
ATOM 1374 C C   . SER B 1 56  ? 236.206 303.281 370.417 1.00 92.71  ? 56  SER B C   1 
ATOM 1375 O O   . SER B 1 56  ? 236.310 302.242 371.075 1.00 92.71  ? 56  SER B O   1 
ATOM 1376 C CB  . SER B 1 56  ? 237.176 305.609 370.476 1.00 92.71  ? 56  SER B CB  1 
ATOM 1377 O OG  . SER B 1 56  ? 238.406 304.949 370.232 1.00 92.71  ? 56  SER B OG  1 
ATOM 1378 N N   . ARG B 1 57  ? 236.136 303.275 369.090 1.00 104.56 ? 57  ARG B N   1 
ATOM 1379 C CA  . ARG B 1 57  ? 236.323 302.050 368.327 1.00 104.56 ? 57  ARG B CA  1 
ATOM 1380 C C   . ARG B 1 57  ? 237.792 301.697 368.151 1.00 104.56 ? 57  ARG B C   1 
ATOM 1381 O O   . ARG B 1 57  ? 238.099 300.681 367.519 1.00 104.56 ? 57  ARG B O   1 
ATOM 1382 C CB  . ARG B 1 57  ? 235.648 302.173 366.959 1.00 104.56 ? 57  ARG B CB  1 
ATOM 1383 C CG  . ARG B 1 57  ? 236.079 303.391 366.160 1.00 104.56 ? 57  ARG B CG  1 
ATOM 1384 C CD  . ARG B 1 57  ? 235.758 303.224 364.684 1.00 104.56 ? 57  ARG B CD  1 
ATOM 1385 N NE  . ARG B 1 57  ? 236.421 302.060 364.108 1.00 104.56 ? 57  ARG B NE  1 
ATOM 1386 C CZ  . ARG B 1 57  ? 237.426 302.120 363.246 1.00 104.56 ? 57  ARG B CZ  1 
ATOM 1387 N NH1 . ARG B 1 57  ? 237.914 303.278 362.831 1.00 104.56 ? 57  ARG B NH1 1 
ATOM 1388 N NH2 . ARG B 1 57  ? 237.955 300.990 362.786 1.00 104.56 ? 57  ARG B NH2 1 
ATOM 1389 N N   . ASN B 1 58  ? 238.701 302.511 368.692 1.00 103.29 ? 58  ASN B N   1 
ATOM 1390 C CA  . ASN B 1 58  ? 240.130 302.269 368.587 1.00 103.29 ? 58  ASN B CA  1 
ATOM 1391 C C   . ASN B 1 58  ? 240.815 302.021 369.923 1.00 103.29 ? 58  ASN B C   1 
ATOM 1392 O O   . ASN B 1 58  ? 241.970 301.582 369.927 1.00 103.29 ? 58  ASN B O   1 
ATOM 1393 C CB  . ASN B 1 58  ? 240.823 303.454 367.894 1.00 103.29 ? 58  ASN B CB  1 
ATOM 1394 C CG  . ASN B 1 58  ? 242.144 303.069 367.263 1.00 103.29 ? 58  ASN B CG  1 
ATOM 1395 O OD1 . ASN B 1 58  ? 242.462 301.888 367.134 1.00 103.29 ? 58  ASN B OD1 1 
ATOM 1396 N ND2 . ASN B 1 58  ? 242.923 304.068 366.866 1.00 103.29 ? 58  ASN B ND2 1 
ATOM 1397 N N   . ARG B 1 59  ? 240.150 302.283 371.047 1.00 89.62  ? 59  ARG B N   1 
ATOM 1398 C CA  . ARG B 1 59  ? 240.763 302.134 372.361 1.00 89.62  ? 59  ARG B CA  1 
ATOM 1399 C C   . ARG B 1 59  ? 240.101 301.056 373.203 1.00 89.62  ? 59  ARG B C   1 
ATOM 1400 O O   . ARG B 1 59  ? 240.792 300.159 373.700 1.00 89.62  ? 59  ARG B O   1 
ATOM 1401 C CB  . ARG B 1 59  ? 240.733 303.476 373.107 1.00 89.62  ? 59  ARG B CB  1 
ATOM 1402 C CG  . ARG B 1 59  ? 241.928 303.706 374.016 1.00 89.62  ? 59  ARG B CG  1 
ATOM 1403 C CD  . ARG B 1 59  ? 242.118 305.184 374.310 1.00 89.62  ? 59  ARG B CD  1 
ATOM 1404 N NE  . ARG B 1 59  ? 240.847 305.868 374.511 1.00 89.62  ? 59  ARG B NE  1 
ATOM 1405 C CZ  . ARG B 1 59  ? 240.412 306.873 373.764 1.00 89.62  ? 59  ARG B CZ  1 
ATOM 1406 N NH1 . ARG B 1 59  ? 241.122 307.339 372.750 1.00 89.62  ? 59  ARG B NH1 1 
ATOM 1407 N NH2 . ARG B 1 59  ? 239.233 307.424 374.041 1.00 89.62  ? 59  ARG B NH2 1 
ATOM 1408 N N   . LYS B 1 60  ? 238.779 301.118 373.377 1.00 83.75  ? 60  LYS B N   1 
ATOM 1409 C CA  . LYS B 1 60  ? 238.034 300.139 374.170 1.00 83.75  ? 60  LYS B CA  1 
ATOM 1410 C C   . LYS B 1 60  ? 238.584 300.046 375.593 1.00 83.75  ? 60  LYS B C   1 
ATOM 1411 O O   . LYS B 1 60  ? 238.712 298.962 376.165 1.00 83.75  ? 60  LYS B O   1 
ATOM 1412 C CB  . LYS B 1 60  ? 238.038 298.764 373.495 1.00 83.75  ? 60  LYS B CB  1 
ATOM 1413 C CG  . LYS B 1 60  ? 237.293 298.710 372.174 1.00 83.75  ? 60  LYS B CG  1 
ATOM 1414 C CD  . LYS B 1 60  ? 237.335 297.311 371.580 1.00 83.75  ? 60  LYS B CD  1 
ATOM 1415 C CE  . LYS B 1 60  ? 236.516 297.229 370.303 1.00 83.75  ? 60  LYS B CE  1 
ATOM 1416 N NZ  . LYS B 1 60  ? 237.111 298.044 369.210 1.00 83.75  ? 60  LYS B NZ  1 
ATOM 1417 N N   . ASN B 1 61  ? 238.911 301.201 376.167 1.00 72.49  ? 61  ASN B N   1 
ATOM 1418 C CA  . ASN B 1 61  ? 239.541 301.233 377.480 1.00 72.49  ? 61  ASN B CA  1 
ATOM 1419 C C   . ASN B 1 61  ? 239.324 302.604 378.100 1.00 72.49  ? 61  ASN B C   1 
ATOM 1420 O O   . ASN B 1 61  ? 239.741 303.614 377.526 1.00 72.49  ? 61  ASN B O   1 
ATOM 1421 C CB  . ASN B 1 61  ? 241.038 300.928 377.367 1.00 72.49  ? 61  ASN B CB  1 
ATOM 1422 C CG  . ASN B 1 61  ? 241.567 300.156 378.555 1.00 72.49  ? 61  ASN B CG  1 
ATOM 1423 O OD1 . ASN B 1 61  ? 240.902 300.044 379.582 1.00 72.49  ? 61  ASN B OD1 1 
ATOM 1424 N ND2 . ASN B 1 61  ? 242.772 299.616 378.420 1.00 72.49  ? 61  ASN B ND2 1 
ATOM 1425 N N   . TYR B 1 62  ? 238.671 302.636 379.260 1.00 63.26  ? 62  TYR B N   1 
ATOM 1426 C CA  . TYR B 1 62  ? 238.460 303.895 379.963 1.00 63.26  ? 62  TYR B CA  1 
ATOM 1427 C C   . TYR B 1 62  ? 239.798 304.516 380.334 1.00 63.26  ? 62  TYR B C   1 
ATOM 1428 O O   . TYR B 1 62  ? 240.730 303.814 380.734 1.00 63.26  ? 62  TYR B O   1 
ATOM 1429 C CB  . TYR B 1 62  ? 237.627 303.671 381.223 1.00 63.26  ? 62  TYR B CB  1 
ATOM 1430 C CG  . TYR B 1 62  ? 236.135 303.702 381.008 1.00 63.26  ? 62  TYR B CG  1 
ATOM 1431 C CD1 . TYR B 1 62  ? 235.560 303.114 379.895 1.00 63.26  ? 62  TYR B CD1 1 
ATOM 1432 C CD2 . TYR B 1 62  ? 235.300 304.322 381.924 1.00 63.26  ? 62  TYR B CD2 1 
ATOM 1433 C CE1 . TYR B 1 62  ? 234.195 303.137 379.705 1.00 63.26  ? 62  TYR B CE1 1 
ATOM 1434 C CE2 . TYR B 1 62  ? 233.938 304.355 381.740 1.00 63.26  ? 62  TYR B CE2 1 
ATOM 1435 C CZ  . TYR B 1 62  ? 233.390 303.762 380.628 1.00 63.26  ? 62  TYR B CZ  1 
ATOM 1436 O OH  . TYR B 1 62  ? 232.028 303.790 380.439 1.00 63.26  ? 62  TYR B OH  1 
ATOM 1437 N N   . LYS B 1 63  ? 239.895 305.835 380.198 1.00 56.29  ? 63  LYS B N   1 
ATOM 1438 C CA  . LYS B 1 63  ? 241.112 306.560 380.533 1.00 56.29  ? 63  LYS B CA  1 
ATOM 1439 C C   . LYS B 1 63  ? 240.759 307.808 381.323 1.00 56.29  ? 63  LYS B C   1 
ATOM 1440 O O   . LYS B 1 63  ? 239.993 308.651 380.847 1.00 56.29  ? 63  LYS B O   1 
ATOM 1441 C CB  . LYS B 1 63  ? 241.895 306.939 379.274 1.00 56.29  ? 63  LYS B CB  1 
ATOM 1442 C CG  . LYS B 1 63  ? 243.343 307.296 379.538 1.00 56.29  ? 63  LYS B CG  1 
ATOM 1443 C CD  . LYS B 1 63  ? 244.164 307.238 378.263 1.00 56.29  ? 63  LYS B CD  1 
ATOM 1444 C CE  . LYS B 1 63  ? 244.166 308.578 377.551 1.00 56.29  ? 63  LYS B CE  1 
ATOM 1445 N NZ  . LYS B 1 63  ? 244.770 309.647 378.394 1.00 56.29  ? 63  LYS B NZ  1 
ATOM 1446 N N   . VAL B 1 64  ? 241.319 307.924 382.522 1.00 53.16  ? 64  VAL B N   1 
ATOM 1447 C CA  . VAL B 1 64  ? 241.191 309.119 383.346 1.00 53.16  ? 64  VAL B CA  1 
ATOM 1448 C C   . VAL B 1 64  ? 242.585 309.697 383.520 1.00 53.16  ? 64  VAL B C   1 
ATOM 1449 O O   . VAL B 1 64  ? 243.484 309.016 384.027 1.00 53.16  ? 64  VAL B O   1 
ATOM 1450 C CB  . VAL B 1 64  ? 240.551 308.817 384.707 1.00 53.16  ? 64  VAL B CB  1 
ATOM 1451 C CG1 . VAL B 1 64  ? 240.667 310.025 385.614 1.00 53.16  ? 64  VAL B CG1 1 
ATOM 1452 C CG2 . VAL B 1 64  ? 239.101 308.425 384.528 1.00 53.16  ? 64  VAL B CG2 1 
ATOM 1453 N N   . GLN B 1 65  ? 242.765 310.947 383.107 1.00 57.94  ? 65  GLN B N   1 
ATOM 1454 C CA  . GLN B 1 65  ? 244.075 311.579 383.068 1.00 57.94  ? 65  GLN B CA  1 
ATOM 1455 C C   . GLN B 1 65  ? 244.041 312.872 383.865 1.00 57.94  ? 65  GLN B C   1 
ATOM 1456 O O   . GLN B 1 65  ? 243.229 313.758 383.584 1.00 57.94  ? 65  GLN B O   1 
ATOM 1457 C CB  . GLN B 1 65  ? 244.495 311.845 381.622 1.00 57.94  ? 65  GLN B CB  1 
ATOM 1458 C CG  . GLN B 1 65  ? 245.853 312.486 381.462 1.00 57.94  ? 65  GLN B CG  1 
ATOM 1459 C CD  . GLN B 1 65  ? 246.367 312.370 380.043 1.00 57.94  ? 65  GLN B CD  1 
ATOM 1460 O OE1 . GLN B 1 65  ? 245.736 311.741 379.194 1.00 57.94  ? 65  GLN B OE1 1 
ATOM 1461 N NE2 . GLN B 1 65  ? 247.519 312.971 379.778 1.00 57.94  ? 65  GLN B NE2 1 
ATOM 1462 N N   . VAL B 1 66  ? 244.925 312.977 384.854 1.00 56.50  ? 66  VAL B N   1 
ATOM 1463 C CA  . VAL B 1 66  ? 245.024 314.149 385.716 1.00 56.50  ? 66  VAL B CA  1 
ATOM 1464 C C   . VAL B 1 66  ? 246.429 314.710 385.576 1.00 56.50  ? 66  VAL B C   1 
ATOM 1465 O O   . VAL B 1 66  ? 247.412 313.978 385.741 1.00 56.50  ? 66  VAL B O   1 
ATOM 1466 C CB  . VAL B 1 66  ? 244.721 313.808 387.182 1.00 56.50  ? 66  VAL B CB  1 
ATOM 1467 C CG1 . VAL B 1 66  ? 245.046 314.990 388.077 1.00 56.50  ? 66  VAL B CG1 1 
ATOM 1468 C CG2 . VAL B 1 66  ? 243.271 313.398 387.337 1.00 56.50  ? 66  VAL B CG2 1 
ATOM 1469 N N   . LYS B 1 67  ? 246.525 316.000 385.276 1.00 61.61  ? 67  LYS B N   1 
ATOM 1470 C CA  . LYS B 1 67  ? 247.805 316.659 385.074 1.00 61.61  ? 67  LYS B CA  1 
ATOM 1471 C C   . LYS B 1 67  ? 247.968 317.826 386.038 1.00 61.61  ? 67  LYS B C   1 
ATOM 1472 O O   . LYS B 1 67  ? 246.999 318.493 386.409 1.00 61.61  ? 67  LYS B O   1 
ATOM 1473 C CB  . LYS B 1 67  ? 247.947 317.155 383.634 1.00 61.61  ? 67  LYS B CB  1 
ATOM 1474 C CG  . LYS B 1 67  ? 249.362 317.088 383.101 1.00 61.61  ? 67  LYS B CG  1 
ATOM 1475 C CD  . LYS B 1 67  ? 249.442 317.647 381.694 1.00 61.61  ? 67  LYS B CD  1 
ATOM 1476 C CE  . LYS B 1 67  ? 248.535 316.881 380.752 1.00 61.61  ? 67  LYS B CE  1 
ATOM 1477 N NZ  . LYS B 1 67  ? 248.704 315.414 380.916 1.00 61.61  ? 67  LYS B NZ  1 
ATOM 1478 N N   . ILE B 1 68  ? 249.213 318.060 386.438 1.00 61.72  ? 68  ILE B N   1 
ATOM 1479 C CA  . ILE B 1 68  ? 249.584 319.149 387.331 1.00 61.72  ? 68  ILE B CA  1 
ATOM 1480 C C   . ILE B 1 68  ? 250.819 319.827 386.758 1.00 61.72  ? 68  ILE B C   1 
ATOM 1481 O O   . ILE B 1 68  ? 251.670 319.169 386.152 1.00 61.72  ? 68  ILE B O   1 
ATOM 1482 C CB  . ILE B 1 68  ? 249.843 318.639 388.767 1.00 61.72  ? 68  ILE B CB  1 
ATOM 1483 C CG1 . ILE B 1 68  ? 249.931 319.801 389.756 1.00 61.72  ? 68  ILE B CG1 1 
ATOM 1484 C CG2 . ILE B 1 68  ? 251.091 317.783 388.829 1.00 61.72  ? 68  ILE B CG2 1 
ATOM 1485 C CD1 . ILE B 1 68  ? 248.650 320.547 389.925 1.00 61.72  ? 68  ILE B CD1 1 
ATOM 1486 N N   . GLN B 1 69  ? 250.900 321.147 386.910 1.00 66.19  ? 69  GLN B N   1 
ATOM 1487 C CA  . GLN B 1 69  ? 252.097 321.869 386.504 1.00 66.19  ? 69  GLN B CA  1 
ATOM 1488 C C   . GLN B 1 69  ? 252.254 323.115 387.358 1.00 66.19  ? 69  GLN B C   1 
ATOM 1489 O O   . GLN B 1 69  ? 251.277 323.812 387.643 1.00 66.19  ? 69  GLN B O   1 
ATOM 1490 C CB  . GLN B 1 69  ? 252.066 322.240 385.016 1.00 66.19  ? 69  GLN B CB  1 
ATOM 1491 C CG  . GLN B 1 69  ? 250.988 323.213 384.604 1.00 66.19  ? 69  GLN B CG  1 
ATOM 1492 C CD  . GLN B 1 69  ? 251.002 323.471 383.113 1.00 66.19  ? 69  GLN B CD  1 
ATOM 1493 O OE1 . GLN B 1 69  ? 250.159 324.201 382.593 1.00 66.19  ? 69  GLN B OE1 1 
ATOM 1494 N NE2 . GLN B 1 69  ? 251.957 322.872 382.415 1.00 66.19  ? 69  GLN B NE2 1 
ATOM 1495 N N   . ASN B 1 70  ? 253.492 323.384 387.768 1.00 68.26  ? 70  ASN B N   1 
ATOM 1496 C CA  . ASN B 1 70  ? 253.819 324.536 388.600 1.00 68.26  ? 70  ASN B CA  1 
ATOM 1497 C C   . ASN B 1 70  ? 254.988 325.273 387.964 1.00 68.26  ? 70  ASN B C   1 
ATOM 1498 O O   . ASN B 1 70  ? 256.047 324.658 387.723 1.00 68.26  ? 70  ASN B O   1 
ATOM 1499 C CB  . ASN B 1 70  ? 254.166 324.111 390.029 1.00 68.26  ? 70  ASN B CB  1 
ATOM 1500 C CG  . ASN B 1 70  ? 252.950 323.714 390.836 1.00 68.26  ? 70  ASN B CG  1 
ATOM 1501 O OD1 . ASN B 1 70  ? 251.885 323.444 390.286 1.00 68.26  ? 70  ASN B OD1 1 
ATOM 1502 N ND2 . ASN B 1 70  ? 253.102 323.681 392.153 1.00 68.26  ? 70  ASN B ND2 1 
ATOM 1503 N N   . PRO B 1 71  ? 254.858 326.559 387.670 1.00 73.94  ? 71  PRO B N   1 
ATOM 1504 C CA  . PRO B 1 71  ? 255.996 327.339 387.188 1.00 73.94  ? 71  PRO B CA  1 
ATOM 1505 C C   . PRO B 1 71  ? 256.735 328.005 388.344 1.00 73.94  ? 71  PRO B C   1 
ATOM 1506 O O   . PRO B 1 71  ? 256.330 327.931 389.504 1.00 73.94  ? 71  PRO B O   1 
ATOM 1507 C CB  . PRO B 1 71  ? 255.328 328.380 386.288 1.00 73.94  ? 71  PRO B CB  1 
ATOM 1508 C CG  . PRO B 1 71  ? 254.026 328.637 386.970 1.00 73.94  ? 71  PRO B CG  1 
ATOM 1509 C CD  . PRO B 1 71  ? 253.611 327.340 387.638 1.00 73.94  ? 71  PRO B CD  1 
ATOM 1510 N N   . THR B 1 72  ? 257.837 328.660 387.999 1.00 90.16  ? 72  THR B N   1 
ATOM 1511 C CA  . THR B 1 72  ? 258.674 329.362 388.961 1.00 90.16  ? 72  THR B CA  1 
ATOM 1512 C C   . THR B 1 72  ? 258.726 330.848 388.630 1.00 90.16  ? 72  THR B C   1 
ATOM 1513 O O   . THR B 1 72  ? 258.400 331.278 387.521 1.00 90.16  ? 72  THR B O   1 
ATOM 1514 C CB  . THR B 1 72  ? 260.090 328.782 388.978 1.00 90.16  ? 72  THR B CB  1 
ATOM 1515 O OG1 . THR B 1 72  ? 260.752 329.105 387.750 1.00 90.16  ? 72  THR B OG1 1 
ATOM 1516 C CG2 . THR B 1 72  ? 260.035 327.281 389.126 1.00 90.16  ? 72  THR B CG2 1 
ATOM 1517 N N   . ALA B 1 73  ? 259.159 331.633 389.611 1.00 104.39 ? 73  ALA B N   1 
ATOM 1518 C CA  . ALA B 1 73  ? 259.211 333.081 389.481 1.00 104.39 ? 73  ALA B CA  1 
ATOM 1519 C C   . ALA B 1 73  ? 260.624 333.578 389.744 1.00 104.39 ? 73  ALA B C   1 
ATOM 1520 O O   . ALA B 1 73  ? 261.249 333.206 390.741 1.00 104.39 ? 73  ALA B O   1 
ATOM 1521 C CB  . ALA B 1 73  ? 258.233 333.761 390.445 1.00 104.39 ? 73  ALA B CB  1 
ATOM 1522 N N   . CYS B 1 74  ? 261.118 334.424 388.843 1.00 109.84 ? 74  CYS B N   1 
ATOM 1523 C CA  . CYS B 1 74  ? 262.427 335.046 388.992 1.00 109.84 ? 74  CYS B CA  1 
ATOM 1524 C C   . CYS B 1 74  ? 262.349 336.461 388.444 1.00 109.84 ? 74  CYS B C   1 
ATOM 1525 O O   . CYS B 1 74  ? 261.874 336.667 387.323 1.00 109.84 ? 74  CYS B O   1 
ATOM 1526 C CB  . CYS B 1 74  ? 263.512 334.249 388.259 1.00 109.84 ? 74  CYS B CB  1 
ATOM 1527 S SG  . CYS B 1 74  ? 263.821 332.602 388.931 1.00 109.84 ? 74  CYS B SG  1 
ATOM 1528 N N   . THR B 1 75  ? 262.813 337.427 389.229 1.00 116.36 ? 75  THR B N   1 
ATOM 1529 C CA  . THR B 1 75  ? 262.762 338.833 388.852 1.00 116.36 ? 75  THR B CA  1 
ATOM 1530 C C   . THR B 1 75  ? 264.113 339.267 388.302 1.00 116.36 ? 75  THR B C   1 
ATOM 1531 O O   . THR B 1 75  ? 265.152 339.009 388.919 1.00 116.36 ? 75  THR B O   1 
ATOM 1532 C CB  . THR B 1 75  ? 262.375 339.707 390.046 1.00 116.36 ? 75  THR B CB  1 
ATOM 1533 O OG1 . THR B 1 75  ? 263.363 339.577 391.074 1.00 116.36 ? 75  THR B OG1 1 
ATOM 1534 C CG2 . THR B 1 75  ? 261.023 339.283 390.595 1.00 116.36 ? 75  THR B CG2 1 
ATOM 1535 N N   . ALA B 1 76  ? 264.093 339.924 387.147 1.00 116.58 ? 76  ALA B N   1 
ATOM 1536 C CA  . ALA B 1 76  ? 265.316 340.401 386.513 1.00 116.58 ? 76  ALA B CA  1 
ATOM 1537 C C   . ALA B 1 76  ? 265.184 341.864 386.099 1.00 116.58 ? 76  ALA B C   1 
ATOM 1538 O O   . ALA B 1 76  ? 264.133 342.293 385.621 1.00 116.58 ? 76  ALA B O   1 
ATOM 1539 C CB  . ALA B 1 76  ? 265.660 339.537 385.310 1.00 116.58 ? 76  ALA B CB  1 
ATOM 1540 N N   . ASP B 1 81  ? 258.973 343.153 384.949 1.00 107.87 ? 81  ASP B N   1 
ATOM 1541 C CA  . ASP B 1 81  ? 258.042 342.033 384.881 1.00 107.87 ? 81  ASP B CA  1 
ATOM 1542 C C   . ASP B 1 81  ? 258.765 340.707 385.090 1.00 107.87 ? 81  ASP B C   1 
ATOM 1543 O O   . ASP B 1 81  ? 259.701 340.386 384.359 1.00 107.87 ? 81  ASP B O   1 
ATOM 1544 C CB  . ASP B 1 81  ? 257.308 342.023 383.540 1.00 107.87 ? 81  ASP B CB  1 
ATOM 1545 C CG  . ASP B 1 81  ? 256.203 343.059 383.472 1.00 107.87 ? 81  ASP B CG  1 
ATOM 1546 O OD1 . ASP B 1 81  ? 255.708 343.473 384.541 1.00 107.87 ? 81  ASP B OD1 1 
ATOM 1547 O OD2 . ASP B 1 81  ? 255.827 343.457 382.349 1.00 107.87 ? 81  ASP B OD2 1 
ATOM 1548 N N   . PRO B 1 82  ? 258.332 339.940 386.087 1.00 101.53 ? 82  PRO B N   1 
ATOM 1549 C CA  . PRO B 1 82  ? 258.973 338.650 386.354 1.00 101.53 ? 82  PRO B CA  1 
ATOM 1550 C C   . PRO B 1 82  ? 258.745 337.668 385.217 1.00 101.53 ? 82  PRO B C   1 
ATOM 1551 O O   . PRO B 1 82  ? 257.735 337.718 384.513 1.00 101.53 ? 82  PRO B O   1 
ATOM 1552 C CB  . PRO B 1 82  ? 258.296 338.177 387.644 1.00 101.53 ? 82  PRO B CB  1 
ATOM 1553 C CG  . PRO B 1 82  ? 256.973 338.856 387.638 1.00 101.53 ? 82  PRO B CG  1 
ATOM 1554 C CD  . PRO B 1 82  ? 257.193 340.191 386.986 1.00 101.53 ? 82  PRO B CD  1 
ATOM 1555 N N   . SER B 1 83  ? 259.705 336.767 385.045 1.00 99.90  ? 83  SER B N   1 
ATOM 1556 C CA  . SER B 1 83  ? 259.669 335.772 383.986 1.00 99.90  ? 83  SER B CA  1 
ATOM 1557 C C   . SER B 1 83  ? 259.626 334.371 384.584 1.00 99.90  ? 83  SER B C   1 
ATOM 1558 O O   . SER B 1 83  ? 259.760 334.177 385.795 1.00 99.90  ? 83  SER B O   1 
ATOM 1559 C CB  . SER B 1 83  ? 260.877 335.917 383.053 1.00 99.90  ? 83  SER B CB  1 
ATOM 1560 O OG  . SER B 1 83  ? 262.085 335.664 383.746 1.00 99.90  ? 83  SER B OG  1 
ATOM 1561 N N   . VAL B 1 84  ? 259.439 333.389 383.709 1.00 93.53  ? 84  VAL B N   1 
ATOM 1562 C CA  . VAL B 1 84  ? 259.364 331.984 384.092 1.00 93.53  ? 84  VAL B CA  1 
ATOM 1563 C C   . VAL B 1 84  ? 260.701 331.323 383.798 1.00 93.53  ? 84  VAL B C   1 
ATOM 1564 O O   . VAL B 1 84  ? 261.287 331.522 382.727 1.00 93.53  ? 84  VAL B O   1 
ATOM 1565 C CB  . VAL B 1 84  ? 258.211 331.270 383.360 1.00 93.53  ? 84  VAL B CB  1 
ATOM 1566 C CG1 . VAL B 1 84  ? 258.338 331.441 381.855 1.00 93.53  ? 84  VAL B CG1 1 
ATOM 1567 C CG2 . VAL B 1 84  ? 258.184 329.800 383.725 1.00 93.53  ? 84  VAL B CG2 1 
ATOM 1568 N N   . THR B 1 85  ? 261.199 330.549 384.759 1.00 87.62  ? 85  THR B N   1 
ATOM 1569 C CA  . THR B 1 85  ? 262.509 329.922 384.649 1.00 87.62  ? 85  THR B CA  1 
ATOM 1570 C C   . THR B 1 85  ? 262.441 328.408 384.538 1.00 87.62  ? 85  THR B C   1 
ATOM 1571 O O   . THR B 1 85  ? 262.986 327.833 383.592 1.00 87.62  ? 85  THR B O   1 
ATOM 1572 C CB  . THR B 1 85  ? 263.378 330.309 385.853 1.00 87.62  ? 85  THR B CB  1 
ATOM 1573 O OG1 . THR B 1 85  ? 263.532 331.732 385.897 1.00 87.62  ? 85  THR B OG1 1 
ATOM 1574 C CG2 . THR B 1 85  ? 264.747 329.662 385.746 1.00 87.62  ? 85  THR B CG2 1 
ATOM 1575 N N   . ARG B 1 86  ? 261.780 327.741 385.480 1.00 85.54  ? 86  ARG B N   1 
ATOM 1576 C CA  . ARG B 1 86  ? 261.760 326.288 385.545 1.00 85.54  ? 86  ARG B CA  1 
ATOM 1577 C C   . ARG B 1 86  ? 260.324 325.788 385.515 1.00 85.54  ? 86  ARG B C   1 
ATOM 1578 O O   . ARG B 1 86  ? 259.448 326.364 386.167 1.00 85.54  ? 86  ARG B O   1 
ATOM 1579 C CB  . ARG B 1 86  ? 262.458 325.788 386.811 1.00 85.54  ? 86  ARG B CB  1 
ATOM 1580 C CG  . ARG B 1 86  ? 263.872 326.305 386.989 1.00 85.54  ? 86  ARG B CG  1 
ATOM 1581 C CD  . ARG B 1 86  ? 264.485 325.768 388.268 1.00 85.54  ? 86  ARG B CD  1 
ATOM 1582 N NE  . ARG B 1 86  ? 263.688 326.113 389.439 1.00 85.54  ? 86  ARG B NE  1 
ATOM 1583 C CZ  . ARG B 1 86  ? 263.846 327.219 390.152 1.00 85.54  ? 86  ARG B CZ  1 
ATOM 1584 N NH1 . ARG B 1 86  ? 264.772 328.113 389.846 1.00 85.54  ? 86  ARG B NH1 1 
ATOM 1585 N NH2 . ARG B 1 86  ? 263.056 327.433 391.200 1.00 85.54  ? 86  ARG B NH2 1 
ATOM 1586 N N   . GLN B 1 87  ? 260.087 324.727 384.755 1.00 77.30  ? 87  GLN B N   1 
ATOM 1587 C CA  . GLN B 1 87  ? 258.818 324.020 384.777 1.00 77.30  ? 87  GLN B CA  1 
ATOM 1588 C C   . GLN B 1 87  ? 258.966 322.731 385.572 1.00 77.30  ? 87  GLN B C   1 
ATOM 1589 O O   . GLN B 1 87  ? 260.008 322.073 385.533 1.00 77.30  ? 87  GLN B O   1 
ATOM 1590 C CB  . GLN B 1 87  ? 258.335 323.708 383.360 1.00 77.30  ? 87  GLN B CB  1 
ATOM 1591 C CG  . GLN B 1 87  ? 258.094 324.935 382.501 1.00 77.30  ? 87  GLN B CG  1 
ATOM 1592 C CD  . GLN B 1 87  ? 256.748 325.576 382.768 1.00 77.30  ? 87  GLN B CD  1 
ATOM 1593 O OE1 . GLN B 1 87  ? 255.740 324.887 382.913 1.00 77.30  ? 87  GLN B OE1 1 
ATOM 1594 N NE2 . GLN B 1 87  ? 256.725 326.900 382.833 1.00 77.30  ? 87  GLN B NE2 1 
ATOM 1595 N N   . ALA B 1 88  ? 257.911 322.376 386.302 1.00 66.35  ? 88  ALA B N   1 
ATOM 1596 C CA  . ALA B 1 88  ? 257.916 321.152 387.104 1.00 66.35  ? 88  ALA B CA  1 
ATOM 1597 C C   . ALA B 1 88  ? 256.492 320.596 387.084 1.00 66.35  ? 88  ALA B C   1 
ATOM 1598 O O   . ALA B 1 88  ? 255.656 320.975 387.905 1.00 66.35  ? 88  ALA B O   1 
ATOM 1599 C CB  . ALA B 1 88  ? 258.397 321.416 388.522 1.00 66.35  ? 88  ALA B CB  1 
ATOM 1600 N N   . TYR B 1 89  ? 256.236 319.690 386.146 1.00 64.95  ? 89  TYR B N   1 
ATOM 1601 C CA  . TYR B 1 89  ? 254.897 319.169 385.927 1.00 64.95  ? 89  TYR B CA  1 
ATOM 1602 C C   . TYR B 1 89  ? 254.885 317.650 386.006 1.00 64.95  ? 89  TYR B C   1 
ATOM 1603 O O   . TYR B 1 89  ? 255.874 316.980 385.698 1.00 64.95  ? 89  TYR B O   1 
ATOM 1604 C CB  . TYR B 1 89  ? 254.334 319.636 384.578 1.00 64.95  ? 89  TYR B CB  1 
ATOM 1605 C CG  . TYR B 1 89  ? 255.139 319.253 383.361 1.00 64.95  ? 89  TYR B CG  1 
ATOM 1606 C CD1 . TYR B 1 89  ? 256.115 320.100 382.859 1.00 64.95  ? 89  TYR B CD1 1 
ATOM 1607 C CD2 . TYR B 1 89  ? 254.899 318.061 382.694 1.00 64.95  ? 89  TYR B CD2 1 
ATOM 1608 C CE1 . TYR B 1 89  ? 256.843 319.763 381.737 1.00 64.95  ? 89  TYR B CE1 1 
ATOM 1609 C CE2 . TYR B 1 89  ? 255.622 317.714 381.571 1.00 64.95  ? 89  TYR B CE2 1 
ATOM 1610 C CZ  . TYR B 1 89  ? 256.593 318.568 381.097 1.00 64.95  ? 89  TYR B CZ  1 
ATOM 1611 O OH  . TYR B 1 89  ? 257.316 318.225 379.978 1.00 64.95  ? 89  TYR B OH  1 
ATOM 1612 N N   . ALA B 1 90  ? 253.739 317.116 386.423 1.00 60.88  ? 90  ALA B N   1 
ATOM 1613 C CA  . ALA B 1 90  ? 253.565 315.687 386.630 1.00 60.88  ? 90  ALA B CA  1 
ATOM 1614 C C   . ALA B 1 90  ? 252.256 315.235 386.003 1.00 60.88  ? 90  ALA B C   1 
ATOM 1615 O O   . ALA B 1 90  ? 251.306 316.012 385.885 1.00 60.88  ? 90  ALA B O   1 
ATOM 1616 C CB  . ALA B 1 90  ? 253.578 315.332 388.118 1.00 60.88  ? 90  ALA B CB  1 
ATOM 1617 N N   . ASP B 1 91  ? 252.213 313.963 385.611 1.00 65.99  ? 91  ASP B N   1 
ATOM 1618 C CA  . ASP B 1 91  ? 251.058 313.387 384.939 1.00 65.99  ? 91  ASP B CA  1 
ATOM 1619 C C   . ASP B 1 91  ? 250.605 312.133 385.668 1.00 65.99  ? 91  ASP B C   1 
ATOM 1620 O O   . ASP B 1 91  ? 251.428 311.362 386.168 1.00 65.99  ? 91  ASP B O   1 
ATOM 1621 C CB  . ASP B 1 91  ? 251.377 313.043 383.482 1.00 65.99  ? 91  ASP B CB  1 
ATOM 1622 C CG  . ASP B 1 91  ? 251.915 314.225 382.710 1.00 65.99  ? 91  ASP B CG  1 
ATOM 1623 O OD1 . ASP B 1 91  ? 252.990 314.738 383.082 1.00 65.99  ? 91  ASP B OD1 1 
ATOM 1624 O OD2 . ASP B 1 91  ? 251.265 314.642 381.729 1.00 65.99  ? 91  ASP B OD2 1 
ATOM 1625 N N   . VAL B 1 92  ? 249.291 311.935 385.725 1.00 57.17  ? 92  VAL B N   1 
ATOM 1626 C CA  . VAL B 1 92  ? 248.688 310.739 386.300 1.00 57.17  ? 92  VAL B CA  1 
ATOM 1627 C C   . VAL B 1 92  ? 247.670 310.212 385.304 1.00 57.17  ? 92  VAL B C   1 
ATOM 1628 O O   . VAL B 1 92  ? 246.759 310.945 384.900 1.00 57.17  ? 92  VAL B O   1 
ATOM 1629 C CB  . VAL B 1 92  ? 248.017 311.023 387.652 1.00 57.17  ? 92  VAL B CB  1 
ATOM 1630 C CG1 . VAL B 1 92  ? 247.259 309.802 388.127 1.00 57.17  ? 92  VAL B CG1 1 
ATOM 1631 C CG2 . VAL B 1 92  ? 249.048 311.441 388.675 1.00 57.17  ? 92  VAL B CG2 1 
ATOM 1632 N N   . THR B 1 93  ? 247.818 308.953 384.904 1.00 57.36  ? 93  THR B N   1 
ATOM 1633 C CA  . THR B 1 93  ? 246.899 308.329 383.963 1.00 57.36  ? 93  THR B CA  1 
ATOM 1634 C C   . THR B 1 93  ? 246.380 307.028 384.551 1.00 57.36  ? 93  THR B C   1 
ATOM 1635 O O   . THR B 1 93  ? 247.166 306.135 384.880 1.00 57.36  ? 93  THR B O   1 
ATOM 1636 C CB  . THR B 1 93  ? 247.571 308.055 382.615 1.00 57.36  ? 93  THR B CB  1 
ATOM 1637 O OG1 . THR B 1 93  ? 248.550 307.021 382.771 1.00 57.36  ? 93  THR B OG1 1 
ATOM 1638 C CG2 . THR B 1 93  ? 248.247 309.308 382.088 1.00 57.36  ? 93  THR B CG2 1 
ATOM 1639 N N   . PHE B 1 94  ? 245.063 306.922 384.674 1.00 54.82  ? 94  PHE B N   1 
ATOM 1640 C CA  . PHE B 1 94  ? 244.412 305.689 385.083 1.00 54.82  ? 94  PHE B CA  1 
ATOM 1641 C C   . PHE B 1 94  ? 243.822 304.990 383.867 1.00 54.82  ? 94  PHE B C   1 
ATOM 1642 O O   . PHE B 1 94  ? 243.405 305.633 382.900 1.00 54.82  ? 94  PHE B O   1 
ATOM 1643 C CB  . PHE B 1 94  ? 243.310 305.961 386.106 1.00 54.82  ? 94  PHE B CB  1 
ATOM 1644 C CG  . PHE B 1 94  ? 243.795 306.613 387.363 1.00 54.82  ? 94  PHE B CG  1 
ATOM 1645 C CD1 . PHE B 1 94  ? 244.525 305.898 388.290 1.00 54.82  ? 94  PHE B CD1 1 
ATOM 1646 C CD2 . PHE B 1 94  ? 243.515 307.940 387.621 1.00 54.82  ? 94  PHE B CD2 1 
ATOM 1647 C CE1 . PHE B 1 94  ? 244.969 306.494 389.450 1.00 54.82  ? 94  PHE B CE1 1 
ATOM 1648 C CE2 . PHE B 1 94  ? 243.957 308.541 388.781 1.00 54.82  ? 94  PHE B CE2 1 
ATOM 1649 C CZ  . PHE B 1 94  ? 244.686 307.818 389.695 1.00 54.82  ? 94  PHE B CZ  1 
ATOM 1650 N N   . SER B 1 95  ? 243.796 303.663 383.919 1.00 59.78  ? 95  SER B N   1 
ATOM 1651 C CA  . SER B 1 95  ? 243.183 302.855 382.874 1.00 59.78  ? 95  SER B CA  1 
ATOM 1652 C C   . SER B 1 95  ? 242.259 301.839 383.522 1.00 59.78  ? 95  SER B C   1 
ATOM 1653 O O   . SER B 1 95  ? 242.665 301.129 384.446 1.00 59.78  ? 95  SER B O   1 
ATOM 1654 C CB  . SER B 1 95  ? 244.240 302.149 382.024 1.00 59.78  ? 95  SER B CB  1 
ATOM 1655 O OG  . SER B 1 95  ? 243.636 301.239 381.124 1.00 59.78  ? 95  SER B OG  1 
ATOM 1656 N N   . PHE B 1 96  ? 241.024 301.768 383.038 1.00 61.64  ? 96  PHE B N   1 
ATOM 1657 C CA  . PHE B 1 96  ? 240.021 300.873 383.590 1.00 61.64  ? 96  PHE B CA  1 
ATOM 1658 C C   . PHE B 1 96  ? 239.288 300.162 382.465 1.00 61.64  ? 96  PHE B C   1 
ATOM 1659 O O   . PHE B 1 96  ? 239.027 300.741 381.408 1.00 61.64  ? 96  PHE B O   1 
ATOM 1660 C CB  . PHE B 1 96  ? 239.018 301.634 384.458 1.00 61.64  ? 96  PHE B CB  1 
ATOM 1661 C CG  . PHE B 1 96  ? 239.608 302.191 385.716 1.00 61.64  ? 96  PHE B CG  1 
ATOM 1662 C CD1 . PHE B 1 96  ? 240.396 301.407 386.532 1.00 61.64  ? 96  PHE B CD1 1 
ATOM 1663 C CD2 . PHE B 1 96  ? 239.387 303.506 386.073 1.00 61.64  ? 96  PHE B CD2 1 
ATOM 1664 C CE1 . PHE B 1 96  ? 240.940 301.920 387.690 1.00 61.64  ? 96  PHE B CE1 1 
ATOM 1665 C CE2 . PHE B 1 96  ? 239.929 304.024 387.228 1.00 61.64  ? 96  PHE B CE2 1 
ATOM 1666 C CZ  . PHE B 1 96  ? 240.707 303.231 388.036 1.00 61.64  ? 96  PHE B CZ  1 
ATOM 1667 N N   . THR B 1 97  ? 238.946 298.903 382.707 1.00 68.78  ? 97  THR B N   1 
ATOM 1668 C CA  . THR B 1 97  ? 238.204 298.103 381.747 1.00 68.78  ? 97  THR B CA  1 
ATOM 1669 C C   . THR B 1 97  ? 236.708 298.336 381.945 1.00 68.78  ? 97  THR B C   1 
ATOM 1670 O O   . THR B 1 97  ? 236.262 298.773 383.007 1.00 68.78  ? 97  THR B O   1 
ATOM 1671 C CB  . THR B 1 97  ? 238.564 296.623 381.909 1.00 68.78  ? 97  THR B CB  1 
ATOM 1672 O OG1 . THR B 1 97  ? 239.981 296.469 381.769 1.00 68.78  ? 97  THR B OG1 1 
ATOM 1673 C CG2 . THR B 1 97  ? 237.899 295.765 380.843 1.00 68.78  ? 97  THR B CG2 1 
ATOM 1674 N N   . GLN B 1 98  ? 235.933 298.054 380.893 1.00 76.59  ? 98  GLN B N   1 
ATOM 1675 C CA  . GLN B 1 98  ? 234.502 298.344 380.909 1.00 76.59  ? 98  GLN B CA  1 
ATOM 1676 C C   . GLN B 1 98  ? 233.804 297.730 382.115 1.00 76.59  ? 98  GLN B C   1 
ATOM 1677 O O   . GLN B 1 98  ? 232.864 298.324 382.653 1.00 76.59  ? 98  GLN B O   1 
ATOM 1678 C CB  . GLN B 1 98  ? 233.855 297.840 379.621 1.00 76.59  ? 98  GLN B CB  1 
ATOM 1679 C CG  . GLN B 1 98  ? 233.917 298.821 378.470 1.00 76.59  ? 98  GLN B CG  1 
ATOM 1680 C CD  . GLN B 1 98  ? 233.924 298.128 377.125 1.00 76.59  ? 98  GLN B CD  1 
ATOM 1681 O OE1 . GLN B 1 98  ? 232.872 297.856 376.549 1.00 76.59  ? 98  GLN B OE1 1 
ATOM 1682 N NE2 . GLN B 1 98  ? 235.115 297.835 376.617 1.00 76.59  ? 98  GLN B NE2 1 
ATOM 1683 N N   . TYR B 1 99  ? 234.244 296.552 382.555 1.00 73.88  ? 99  TYR B N   1 
ATOM 1684 C CA  . TYR B 1 99  ? 233.637 295.865 383.687 1.00 73.88  ? 99  TYR B CA  1 
ATOM 1685 C C   . TYR B 1 99  ? 234.376 296.135 384.992 1.00 73.88  ? 99  TYR B C   1 
ATOM 1686 O O   . TYR B 1 99  ? 234.344 295.306 385.908 1.00 73.88  ? 99  TYR B O   1 
ATOM 1687 C CB  . TYR B 1 99  ? 233.565 294.364 383.415 1.00 73.88  ? 99  TYR B CB  1 
ATOM 1688 C CG  . TYR B 1 99  ? 232.921 294.022 382.093 1.00 73.88  ? 99  TYR B CG  1 
ATOM 1689 C CD1 . TYR B 1 99  ? 231.544 293.908 381.981 1.00 73.88  ? 99  TYR B CD1 1 
ATOM 1690 C CD2 . TYR B 1 99  ? 233.690 293.816 380.958 1.00 73.88  ? 99  TYR B CD2 1 
ATOM 1691 C CE1 . TYR B 1 99  ? 230.951 293.599 380.776 1.00 73.88  ? 99  TYR B CE1 1 
ATOM 1692 C CE2 . TYR B 1 99  ? 233.106 293.507 379.749 1.00 73.88  ? 99  TYR B CE2 1 
ATOM 1693 C CZ  . TYR B 1 99  ? 231.736 293.399 379.664 1.00 73.88  ? 99  TYR B CZ  1 
ATOM 1694 O OH  . TYR B 1 99  ? 231.150 293.089 378.459 1.00 73.88  ? 99  TYR B OH  1 
ATOM 1695 N N   . SER B 1 100 ? 235.045 297.279 385.096 1.00 75.09  ? 100 SER B N   1 
ATOM 1696 C CA  . SER B 1 100 ? 235.732 297.640 386.328 1.00 75.09  ? 100 SER B CA  1 
ATOM 1697 C C   . SER B 1 100 ? 234.709 298.022 387.388 1.00 75.09  ? 100 SER B C   1 
ATOM 1698 O O   . SER B 1 100 ? 233.860 298.887 387.154 1.00 75.09  ? 100 SER B O   1 
ATOM 1699 C CB  . SER B 1 100 ? 236.695 298.795 386.076 1.00 75.09  ? 100 SER B CB  1 
ATOM 1700 O OG  . SER B 1 100 ? 237.667 298.445 385.106 1.00 75.09  ? 100 SER B OG  1 
ATOM 1701 N N   . THR B 1 101 ? 234.786 297.386 388.551 1.00 77.54  ? 101 THR B N   1 
ATOM 1702 C CA  . THR B 1 101 ? 233.857 297.705 389.620 1.00 77.54  ? 101 THR B CA  1 
ATOM 1703 C C   . THR B 1 101 ? 234.215 299.046 390.256 1.00 77.54  ? 101 THR B C   1 
ATOM 1704 O O   . THR B 1 101 ? 235.290 299.609 390.033 1.00 77.54  ? 101 THR B O   1 
ATOM 1705 C CB  . THR B 1 101 ? 233.859 296.607 390.680 1.00 77.54  ? 101 THR B CB  1 
ATOM 1706 O OG1 . THR B 1 101 ? 235.112 296.617 391.374 1.00 77.54  ? 101 THR B OG1 1 
ATOM 1707 C CG2 . THR B 1 101 ? 233.659 295.249 390.035 1.00 77.54  ? 101 THR B CG2 1 
ATOM 1708 N N   . ASP B 1 102 ? 233.284 299.566 391.057 1.00 83.25  ? 102 ASP B N   1 
ATOM 1709 C CA  . ASP B 1 102 ? 233.559 300.785 391.808 1.00 83.25  ? 102 ASP B CA  1 
ATOM 1710 C C   . ASP B 1 102 ? 234.583 300.529 392.905 1.00 83.25  ? 102 ASP B C   1 
ATOM 1711 O O   . ASP B 1 102 ? 235.475 301.356 393.141 1.00 83.25  ? 102 ASP B O   1 
ATOM 1712 C CB  . ASP B 1 102 ? 232.266 301.336 392.402 1.00 83.25  ? 102 ASP B CB  1 
ATOM 1713 C CG  . ASP B 1 102 ? 231.203 301.580 391.354 1.00 83.25  ? 102 ASP B CG  1 
ATOM 1714 O OD1 . ASP B 1 102 ? 231.484 301.353 390.159 1.00 83.25  ? 102 ASP B OD1 1 
ATOM 1715 O OD2 . ASP B 1 102 ? 230.085 301.996 391.724 1.00 83.25  ? 102 ASP B OD2 1 
ATOM 1716 N N   . GLU B 1 103 ? 234.472 299.381 393.578 1.00 87.75  ? 103 GLU B N   1 
ATOM 1717 C CA  . GLU B 1 103 ? 235.413 299.042 394.639 1.00 87.75  ? 103 GLU B CA  1 
ATOM 1718 C C   . GLU B 1 103 ? 236.839 298.991 394.114 1.00 87.75  ? 103 GLU B C   1 
ATOM 1719 O O   . GLU B 1 103 ? 237.760 299.509 394.751 1.00 87.75  ? 103 GLU B O   1 
ATOM 1720 C CB  . GLU B 1 103 ? 235.031 297.701 395.264 1.00 87.75  ? 103 GLU B CB  1 
ATOM 1721 C CG  . GLU B 1 103 ? 235.923 297.264 396.412 1.00 87.75  ? 103 GLU B CG  1 
ATOM 1722 C CD  . GLU B 1 103 ? 235.829 298.181 397.613 1.00 87.75  ? 103 GLU B CD  1 
ATOM 1723 O OE1 . GLU B 1 103 ? 234.781 298.837 397.782 1.00 87.75  ? 103 GLU B OE1 1 
ATOM 1724 O OE2 . GLU B 1 103 ? 236.805 298.245 398.389 1.00 87.75  ? 103 GLU B OE2 1 
ATOM 1725 N N   . GLU B 1 104 ? 237.034 298.386 392.943 1.00 80.36  ? 104 GLU B N   1 
ATOM 1726 C CA  . GLU B 1 104 ? 238.374 298.243 392.385 1.00 80.36  ? 104 GLU B CA  1 
ATOM 1727 C C   . GLU B 1 104 ? 238.999 299.603 392.088 1.00 80.36  ? 104 GLU B C   1 
ATOM 1728 O O   . GLU B 1 104 ? 240.141 299.876 392.480 1.00 80.36  ? 104 GLU B O   1 
ATOM 1729 C CB  . GLU B 1 104 ? 238.301 297.385 391.125 1.00 80.36  ? 104 GLU B CB  1 
ATOM 1730 C CG  . GLU B 1 104 ? 239.598 296.732 390.717 1.00 80.36  ? 104 GLU B CG  1 
ATOM 1731 C CD  . GLU B 1 104 ? 239.640 296.441 389.234 1.00 80.36  ? 104 GLU B CD  1 
ATOM 1732 O OE1 . GLU B 1 104 ? 240.742 296.453 388.654 1.00 80.36  ? 104 GLU B OE1 1 
ATOM 1733 O OE2 . GLU B 1 104 ? 238.566 296.203 388.644 1.00 80.36  ? 104 GLU B OE2 1 
ATOM 1734 N N   . ARG B 1 105 ? 238.261 300.470 391.390 1.00 75.43  ? 105 ARG B N   1 
ATOM 1735 C CA  . ARG B 1 105 ? 238.797 301.782 391.046 1.00 75.43  ? 105 ARG B CA  1 
ATOM 1736 C C   . ARG B 1 105 ? 239.076 302.609 392.292 1.00 75.43  ? 105 ARG B C   1 
ATOM 1737 O O   . ARG B 1 105 ? 240.131 303.249 392.399 1.00 75.43  ? 105 ARG B O   1 
ATOM 1738 C CB  . ARG B 1 105 ? 237.827 302.525 390.131 1.00 75.43  ? 105 ARG B CB  1 
ATOM 1739 C CG  . ARG B 1 105 ? 237.566 301.852 388.802 1.00 75.43  ? 105 ARG B CG  1 
ATOM 1740 C CD  . ARG B 1 105 ? 236.637 302.700 387.956 1.00 75.43  ? 105 ARG B CD  1 
ATOM 1741 N NE  . ARG B 1 105 ? 235.293 302.750 388.514 1.00 75.43  ? 105 ARG B NE  1 
ATOM 1742 C CZ  . ARG B 1 105 ? 234.297 301.969 388.124 1.00 75.43  ? 105 ARG B CZ  1 
ATOM 1743 N NH1 . ARG B 1 105 ? 234.453 301.085 387.154 1.00 75.43  ? 105 ARG B NH1 1 
ATOM 1744 N NH2 . ARG B 1 105 ? 233.114 302.083 388.717 1.00 75.43  ? 105 ARG B NH2 1 
ATOM 1745 N N   . ALA B 1 106 ? 238.137 302.618 393.242 1.00 83.81  ? 106 ALA B N   1 
ATOM 1746 C CA  . ALA B 1 106 ? 238.346 303.386 394.463 1.00 83.81  ? 106 ALA B CA  1 
ATOM 1747 C C   . ALA B 1 106 ? 239.553 302.869 395.228 1.00 83.81  ? 106 ALA B C   1 
ATOM 1748 O O   . ALA B 1 106 ? 240.346 303.655 395.759 1.00 83.81  ? 106 ALA B O   1 
ATOM 1749 C CB  . ALA B 1 106 ? 237.095 303.342 395.337 1.00 83.81  ? 106 ALA B CB  1 
ATOM 1750 N N   . PHE B 1 107 ? 239.709 301.545 395.289 1.00 77.65  ? 107 PHE B N   1 
ATOM 1751 C CA  . PHE B 1 107 ? 240.858 300.953 395.959 1.00 77.65  ? 107 PHE B CA  1 
ATOM 1752 C C   . PHE B 1 107 ? 242.158 301.389 395.305 1.00 77.65  ? 107 PHE B C   1 
ATOM 1753 O O   . PHE B 1 107 ? 243.101 301.792 395.995 1.00 77.65  ? 107 PHE B O   1 
ATOM 1754 C CB  . PHE B 1 107 ? 240.727 299.432 395.937 1.00 77.65  ? 107 PHE B CB  1 
ATOM 1755 C CG  . PHE B 1 107 ? 241.910 298.711 396.501 1.00 77.65  ? 107 PHE B CG  1 
ATOM 1756 C CD1 . PHE B 1 107 ? 242.177 298.741 397.856 1.00 77.65  ? 107 PHE B CD1 1 
ATOM 1757 C CD2 . PHE B 1 107 ? 242.754 297.998 395.672 1.00 77.65  ? 107 PHE B CD2 1 
ATOM 1758 C CE1 . PHE B 1 107 ? 243.265 298.071 398.373 1.00 77.65  ? 107 PHE B CE1 1 
ATOM 1759 C CE2 . PHE B 1 107 ? 243.843 297.330 396.183 1.00 77.65  ? 107 PHE B CE2 1 
ATOM 1760 C CZ  . PHE B 1 107 ? 244.099 297.365 397.535 1.00 77.65  ? 107 PHE B CZ  1 
ATOM 1761 N N   . VAL B 1 108 ? 242.222 301.333 393.972 1.00 73.20  ? 108 VAL B N   1 
ATOM 1762 C CA  . VAL B 1 108 ? 243.439 301.741 393.271 1.00 73.20  ? 108 VAL B CA  1 
ATOM 1763 C C   . VAL B 1 108 ? 243.762 303.195 393.580 1.00 73.20  ? 108 VAL B C   1 
ATOM 1764 O O   . VAL B 1 108 ? 244.895 303.537 393.946 1.00 73.20  ? 108 VAL B O   1 
ATOM 1765 C CB  . VAL B 1 108 ? 243.293 301.512 391.757 1.00 73.20  ? 108 VAL B CB  1 
ATOM 1766 C CG1 . VAL B 1 108 ? 244.327 302.325 391.000 1.00 73.20  ? 108 VAL B CG1 1 
ATOM 1767 C CG2 . VAL B 1 108 ? 243.434 300.043 391.429 1.00 73.20  ? 108 VAL B CG2 1 
ATOM 1768 N N   . ARG B 1 109 ? 242.760 304.068 393.460 1.00 76.40  ? 109 ARG B N   1 
ATOM 1769 C CA  . ARG B 1 109 ? 242.984 305.490 393.695 1.00 76.40  ? 109 ARG B CA  1 
ATOM 1770 C C   . ARG B 1 109 ? 243.498 305.743 395.104 1.00 76.40  ? 109 ARG B C   1 
ATOM 1771 O O   . ARG B 1 109 ? 244.526 306.406 395.295 1.00 76.40  ? 109 ARG B O   1 
ATOM 1772 C CB  . ARG B 1 109 ? 241.695 306.271 393.470 1.00 76.40  ? 109 ARG B CB  1 
ATOM 1773 C CG  . ARG B 1 109 ? 241.787 307.700 393.954 1.00 76.40  ? 109 ARG B CG  1 
ATOM 1774 C CD  . ARG B 1 109 ? 240.424 308.341 394.028 1.00 76.40  ? 109 ARG B CD  1 
ATOM 1775 N NE  . ARG B 1 109 ? 239.620 307.716 395.069 1.00 76.40  ? 109 ARG B NE  1 
ATOM 1776 C CZ  . ARG B 1 109 ? 239.748 307.967 396.364 1.00 76.40  ? 109 ARG B CZ  1 
ATOM 1777 N NH1 . ARG B 1 109 ? 240.649 308.822 396.817 1.00 76.40  ? 109 ARG B NH1 1 
ATOM 1778 N NH2 . ARG B 1 109 ? 238.947 307.349 397.228 1.00 76.40  ? 109 ARG B NH2 1 
ATOM 1779 N N   . THR B 1 110 ? 242.796 305.220 396.111 1.00 78.84  ? 110 THR B N   1 
ATOM 1780 C CA  . THR B 1 110 ? 243.159 305.557 397.480 1.00 78.84  ? 110 THR B CA  1 
ATOM 1781 C C   . THR B 1 110 ? 244.476 304.915 397.890 1.00 78.84  ? 110 THR B C   1 
ATOM 1782 O O   . THR B 1 110 ? 245.222 305.503 398.681 1.00 78.84  ? 110 THR B O   1 
ATOM 1783 C CB  . THR B 1 110 ? 242.046 305.161 398.448 1.00 78.84  ? 110 THR B CB  1 
ATOM 1784 O OG1 . THR B 1 110 ? 242.395 305.584 399.772 1.00 78.84  ? 110 THR B OG1 1 
ATOM 1785 C CG2 . THR B 1 110 ? 241.843 303.665 398.447 1.00 78.84  ? 110 THR B CG2 1 
ATOM 1786 N N   . GLU B 1 111 ? 244.806 303.733 397.360 1.00 75.04  ? 111 GLU B N   1 
ATOM 1787 C CA  . GLU B 1 111 ? 246.080 303.138 397.738 1.00 75.04  ? 111 GLU B CA  1 
ATOM 1788 C C   . GLU B 1 111 ? 247.230 303.860 397.054 1.00 75.04  ? 111 GLU B C   1 
ATOM 1789 O O   . GLU B 1 111 ? 248.311 303.994 397.634 1.00 75.04  ? 111 GLU B O   1 
ATOM 1790 C CB  . GLU B 1 111 ? 246.097 301.639 397.431 1.00 75.04  ? 111 GLU B CB  1 
ATOM 1791 C CG  . GLU B 1 111 ? 246.158 301.250 395.969 1.00 75.04  ? 111 GLU B CG  1 
ATOM 1792 C CD  . GLU B 1 111 ? 247.581 301.072 395.486 1.00 75.04  ? 111 GLU B CD  1 
ATOM 1793 O OE1 . GLU B 1 111 ? 248.481 300.930 396.337 1.00 75.04  ? 111 GLU B OE1 1 
ATOM 1794 O OE2 . GLU B 1 111 ? 247.797 301.051 394.261 1.00 75.04  ? 111 GLU B OE2 1 
ATOM 1795 N N   . LEU B 1 112 ? 247.009 304.371 395.838 1.00 71.23  ? 112 LEU B N   1 
ATOM 1796 C CA  . LEU B 1 112 ? 248.005 305.254 395.240 1.00 71.23  ? 112 LEU B CA  1 
ATOM 1797 C C   . LEU B 1 112 ? 248.193 306.507 396.081 1.00 71.23  ? 112 LEU B C   1 
ATOM 1798 O O   . LEU B 1 112 ? 249.326 306.945 396.314 1.00 71.23  ? 112 LEU B O   1 
ATOM 1799 C CB  . LEU B 1 112 ? 247.599 305.629 393.817 1.00 71.23  ? 112 LEU B CB  1 
ATOM 1800 C CG  . LEU B 1 112 ? 248.556 306.588 393.110 1.00 71.23  ? 112 LEU B CG  1 
ATOM 1801 C CD1 . LEU B 1 112 ? 249.961 306.025 393.104 1.00 71.23  ? 112 LEU B CD1 1 
ATOM 1802 C CD2 . LEU B 1 112 ? 248.087 306.864 391.698 1.00 71.23  ? 112 LEU B CD2 1 
ATOM 1803 N N   . ALA B 1 113 ? 247.091 307.091 396.553 1.00 73.03  ? 113 ALA B N   1 
ATOM 1804 C CA  . ALA B 1 113 ? 247.185 308.299 397.367 1.00 73.03  ? 113 ALA B CA  1 
ATOM 1805 C C   . ALA B 1 113 ? 247.959 308.038 398.652 1.00 73.03  ? 113 ALA B C   1 
ATOM 1806 O O   . ALA B 1 113 ? 248.804 308.844 399.057 1.00 73.03  ? 113 ALA B O   1 
ATOM 1807 C CB  . ALA B 1 113 ? 245.787 308.829 397.683 1.00 73.03  ? 113 ALA B CB  1 
ATOM 1808 N N   . ALA B 1 114 ? 247.683 306.911 399.309 1.00 73.68  ? 114 ALA B N   1 
ATOM 1809 C CA  . ALA B 1 114 ? 248.362 306.604 400.564 1.00 73.68  ? 114 ALA B CA  1 
ATOM 1810 C C   . ALA B 1 114 ? 249.833 306.280 400.333 1.00 73.68  ? 114 ALA B C   1 
ATOM 1811 O O   . ALA B 1 114 ? 250.708 306.789 401.043 1.00 73.68  ? 114 ALA B O   1 
ATOM 1812 C CB  . ALA B 1 114 ? 247.661 305.447 401.273 1.00 73.68  ? 114 ALA B CB  1 
ATOM 1813 N N   . LEU B 1 115 ? 250.128 305.434 399.343 1.00 74.64  ? 115 LEU B N   1 
ATOM 1814 C CA  . LEU B 1 115 ? 251.506 305.068 399.049 1.00 74.64  ? 115 LEU B CA  1 
ATOM 1815 C C   . LEU B 1 115 ? 252.324 306.253 398.560 1.00 74.64  ? 115 LEU B C   1 
ATOM 1816 O O   . LEU B 1 115 ? 253.552 306.241 398.696 1.00 74.64  ? 115 LEU B O   1 
ATOM 1817 C CB  . LEU B 1 115 ? 251.527 303.938 398.018 1.00 74.64  ? 115 LEU B CB  1 
ATOM 1818 C CG  . LEU B 1 115 ? 252.866 303.370 397.553 1.00 74.64  ? 115 LEU B CG  1 
ATOM 1819 C CD1 . LEU B 1 115 ? 252.810 301.858 397.527 1.00 74.64  ? 115 LEU B CD1 1 
ATOM 1820 C CD2 . LEU B 1 115 ? 253.190 303.897 396.174 1.00 74.64  ? 115 LEU B CD2 1 
ATOM 1821 N N   . LEU B 1 116 ? 251.678 307.281 398.009 1.00 77.03  ? 116 LEU B N   1 
ATOM 1822 C CA  . LEU B 1 116 ? 252.415 308.456 397.570 1.00 77.03  ? 116 LEU B CA  1 
ATOM 1823 C C   . LEU B 1 116 ? 252.977 309.257 398.738 1.00 77.03  ? 116 LEU B C   1 
ATOM 1824 O O   . LEU B 1 116 ? 253.875 310.079 398.530 1.00 77.03  ? 116 LEU B O   1 
ATOM 1825 C CB  . LEU B 1 116 ? 251.514 309.331 396.698 1.00 77.03  ? 116 LEU B CB  1 
ATOM 1826 C CG  . LEU B 1 116 ? 252.122 310.585 396.076 1.00 77.03  ? 116 LEU B CG  1 
ATOM 1827 C CD1 . LEU B 1 116 ? 253.239 310.191 395.132 1.00 77.03  ? 116 LEU B CD1 1 
ATOM 1828 C CD2 . LEU B 1 116 ? 251.064 311.378 395.339 1.00 77.03  ? 116 LEU B CD2 1 
ATOM 1829 N N   . ALA B 1 117 ? 252.492 309.025 399.955 1.00 78.33  ? 117 ALA B N   1 
ATOM 1830 C CA  . ALA B 1 117 ? 253.035 309.657 401.148 1.00 78.33  ? 117 ALA B CA  1 
ATOM 1831 C C   . ALA B 1 117 ? 253.938 308.723 401.946 1.00 78.33  ? 117 ALA B C   1 
ATOM 1832 O O   . ALA B 1 117 ? 254.338 309.068 403.061 1.00 78.33  ? 117 ALA B O   1 
ATOM 1833 C CB  . ALA B 1 117 ? 251.903 310.172 402.036 1.00 78.33  ? 117 ALA B CB  1 
ATOM 1834 N N   . SER B 1 118 ? 254.257 307.551 401.405 1.00 80.85  ? 118 SER B N   1 
ATOM 1835 C CA  . SER B 1 118 ? 255.130 306.619 402.098 1.00 80.85  ? 118 SER B CA  1 
ATOM 1836 C C   . SER B 1 118 ? 256.568 307.139 402.104 1.00 80.85  ? 118 SER B C   1 
ATOM 1837 O O   . SER B 1 118 ? 256.987 307.831 401.174 1.00 80.85  ? 118 SER B O   1 
ATOM 1838 C CB  . SER B 1 118 ? 255.077 305.248 401.433 1.00 80.85  ? 118 SER B CB  1 
ATOM 1839 O OG  . SER B 1 118 ? 256.061 304.379 401.962 1.00 80.85  ? 118 SER B OG  1 
ATOM 1840 N N   . PRO B 1 119 ? 257.344 306.814 403.143 1.00 89.54  ? 119 PRO B N   1 
ATOM 1841 C CA  . PRO B 1 119 ? 258.731 307.304 403.201 1.00 89.54  ? 119 PRO B CA  1 
ATOM 1842 C C   . PRO B 1 119 ? 259.566 306.914 401.996 1.00 89.54  ? 119 PRO B C   1 
ATOM 1843 O O   . PRO B 1 119 ? 260.424 307.699 401.569 1.00 89.54  ? 119 PRO B O   1 
ATOM 1844 C CB  . PRO B 1 119 ? 259.270 306.666 404.487 1.00 89.54  ? 119 PRO B CB  1 
ATOM 1845 C CG  . PRO B 1 119 ? 258.066 306.471 405.332 1.00 89.54  ? 119 PRO B CG  1 
ATOM 1846 C CD  . PRO B 1 119 ? 256.949 306.132 404.387 1.00 89.54  ? 119 PRO B CD  1 
ATOM 1847 N N   . LEU B 1 120 ? 259.341 305.724 401.436 1.00 83.94  ? 120 LEU B N   1 
ATOM 1848 C CA  . LEU B 1 120 ? 260.070 305.319 400.241 1.00 83.94  ? 120 LEU B CA  1 
ATOM 1849 C C   . LEU B 1 120 ? 259.899 306.342 399.127 1.00 83.94  ? 120 LEU B C   1 
ATOM 1850 O O   . LEU B 1 120 ? 260.879 306.795 398.526 1.00 83.94  ? 120 LEU B O   1 
ATOM 1851 C CB  . LEU B 1 120 ? 259.598 303.939 399.784 1.00 83.94  ? 120 LEU B CB  1 
ATOM 1852 C CG  . LEU B 1 120 ? 260.227 303.373 398.510 1.00 83.94  ? 120 LEU B CG  1 
ATOM 1853 C CD1 . LEU B 1 120 ? 260.511 301.898 398.686 1.00 83.94  ? 120 LEU B CD1 1 
ATOM 1854 C CD2 . LEU B 1 120 ? 259.318 303.591 397.310 1.00 83.94  ? 120 LEU B CD2 1 
ATOM 1855 N N   . LEU B 1 121 ? 258.659 306.743 398.856 1.00 82.48  ? 121 LEU B N   1 
ATOM 1856 C CA  . LEU B 1 121 ? 258.438 307.692 397.774 1.00 82.48  ? 121 LEU B CA  1 
ATOM 1857 C C   . LEU B 1 121 ? 258.916 309.095 398.118 1.00 82.48  ? 121 LEU B C   1 
ATOM 1858 O O   . LEU B 1 121 ? 259.376 309.813 397.226 1.00 82.48  ? 121 LEU B O   1 
ATOM 1859 C CB  . LEU B 1 121 ? 256.964 307.724 397.377 1.00 82.48  ? 121 LEU B CB  1 
ATOM 1860 C CG  . LEU B 1 121 ? 256.558 306.590 396.438 1.00 82.48  ? 121 LEU B CG  1 
ATOM 1861 C CD1 . LEU B 1 121 ? 255.181 306.846 395.861 1.00 82.48  ? 121 LEU B CD1 1 
ATOM 1862 C CD2 . LEU B 1 121 ? 257.583 306.427 395.332 1.00 82.48  ? 121 LEU B CD2 1 
ATOM 1863 N N   . ILE B 1 122 ? 258.827 309.517 399.380 1.00 86.01  ? 122 ILE B N   1 
ATOM 1864 C CA  . ILE B 1 122 ? 259.302 310.859 399.701 1.00 86.01  ? 122 ILE B CA  1 
ATOM 1865 C C   . ILE B 1 122 ? 260.818 310.936 399.555 1.00 86.01  ? 122 ILE B C   1 
ATOM 1866 O O   . ILE B 1 122 ? 261.355 311.954 399.105 1.00 86.01  ? 122 ILE B O   1 
ATOM 1867 C CB  . ILE B 1 122 ? 258.822 311.308 401.095 1.00 86.01  ? 122 ILE B CB  1 
ATOM 1868 C CG1 . ILE B 1 122 ? 259.647 310.675 402.213 1.00 86.01  ? 122 ILE B CG1 1 
ATOM 1869 C CG2 . ILE B 1 122 ? 257.347 311.009 401.271 1.00 86.01  ? 122 ILE B CG2 1 
ATOM 1870 C CD1 . ILE B 1 122 ? 259.506 311.387 403.533 1.00 86.01  ? 122 ILE B CD1 1 
ATOM 1871 N N   . ASP B 1 123 ? 261.533 309.862 399.902 1.00 87.25  ? 123 ASP B N   1 
ATOM 1872 C CA  . ASP B 1 123 ? 262.966 309.845 399.638 1.00 87.25  ? 123 ASP B CA  1 
ATOM 1873 C C   . ASP B 1 123 ? 263.292 309.613 398.170 1.00 87.25  ? 123 ASP B C   1 
ATOM 1874 O O   . ASP B 1 123 ? 264.380 309.992 397.726 1.00 87.25  ? 123 ASP B O   1 
ATOM 1875 C CB  . ASP B 1 123 ? 263.663 308.784 400.492 1.00 87.25  ? 123 ASP B CB  1 
ATOM 1876 C CG  . ASP B 1 123 ? 263.673 309.138 401.965 1.00 87.25  ? 123 ASP B CG  1 
ATOM 1877 O OD1 . ASP B 1 123 ? 263.674 310.345 402.286 1.00 87.25  ? 123 ASP B OD1 1 
ATOM 1878 O OD2 . ASP B 1 123 ? 263.690 308.212 402.801 1.00 87.25  ? 123 ASP B OD2 1 
ATOM 1879 N N   . ALA B 1 124 ? 262.384 309.005 397.408 1.00 78.37  ? 124 ALA B N   1 
ATOM 1880 C CA  . ALA B 1 124 ? 262.601 308.847 395.977 1.00 78.37  ? 124 ALA B CA  1 
ATOM 1881 C C   . ALA B 1 124 ? 262.253 310.097 395.181 1.00 78.37  ? 124 ALA B C   1 
ATOM 1882 O O   . ALA B 1 124 ? 262.636 310.193 394.011 1.00 78.37  ? 124 ALA B O   1 
ATOM 1883 C CB  . ALA B 1 124 ? 261.785 307.666 395.449 1.00 78.37  ? 124 ALA B CB  1 
ATOM 1884 N N   . ILE B 1 125 ? 261.534 311.043 395.778 1.00 78.18  ? 125 ILE B N   1 
ATOM 1885 C CA  . ILE B 1 125 ? 261.112 312.265 395.097 1.00 78.18  ? 125 ILE B CA  1 
ATOM 1886 C C   . ILE B 1 125 ? 261.909 313.474 395.574 1.00 78.18  ? 125 ILE B C   1 
ATOM 1887 O O   . ILE B 1 125 ? 262.521 314.179 394.771 1.00 78.18  ? 125 ILE B O   1 
ATOM 1888 C CB  . ILE B 1 125 ? 259.595 312.498 395.264 1.00 78.18  ? 125 ILE B CB  1 
ATOM 1889 C CG1 . ILE B 1 125 ? 258.816 311.406 394.540 1.00 78.18  ? 125 ILE B CG1 1 
ATOM 1890 C CG2 . ILE B 1 125 ? 259.211 313.868 394.744 1.00 78.18  ? 125 ILE B CG2 1 
ATOM 1891 C CD1 . ILE B 1 125 ? 259.152 311.315 393.085 1.00 78.18  ? 125 ILE B CD1 1 
ATOM 1892 N N   . ASP B 1 126 ? 261.900 313.740 396.881 1.00 87.60  ? 126 ASP B N   1 
ATOM 1893 C CA  . ASP B 1 126 ? 262.500 314.971 397.382 1.00 87.60  ? 126 ASP B CA  1 
ATOM 1894 C C   . ASP B 1 126 ? 264.010 314.988 397.176 1.00 87.60  ? 126 ASP B C   1 
ATOM 1895 O O   . ASP B 1 126 ? 264.577 316.021 396.801 1.00 87.60  ? 126 ASP B O   1 
ATOM 1896 C CB  . ASP B 1 126 ? 262.150 315.154 398.854 1.00 87.60  ? 126 ASP B CB  1 
ATOM 1897 C CG  . ASP B 1 126 ? 260.723 315.615 399.054 1.00 87.60  ? 126 ASP B CG  1 
ATOM 1898 O OD1 . ASP B 1 126 ? 259.987 315.709 398.050 1.00 87.60  ? 126 ASP B OD1 1 
ATOM 1899 O OD2 . ASP B 1 126 ? 260.337 315.884 400.209 1.00 87.60  ? 126 ASP B OD2 1 
ATOM 1900 N N   . GLN B 1 127 ? 264.680 313.863 397.415 1.00 87.10  ? 127 GLN B N   1 
ATOM 1901 C CA  . GLN B 1 127 ? 266.115 313.758 397.194 1.00 87.10  ? 127 GLN B CA  1 
ATOM 1902 C C   . GLN B 1 127 ? 266.469 312.886 395.999 1.00 87.10  ? 127 GLN B C   1 
ATOM 1903 O O   . GLN B 1 127 ? 267.653 312.759 395.672 1.00 87.10  ? 127 GLN B O   1 
ATOM 1904 C CB  . GLN B 1 127 ? 266.807 313.220 398.450 1.00 87.10  ? 127 GLN B CB  1 
ATOM 1905 C CG  . GLN B 1 127 ? 267.153 314.295 399.460 1.00 87.10  ? 127 GLN B CG  1 
ATOM 1906 C CD  . GLN B 1 127 ? 266.004 314.608 400.391 1.00 87.10  ? 127 GLN B CD  1 
ATOM 1907 O OE1 . GLN B 1 127 ? 264.865 314.222 400.140 1.00 87.10  ? 127 GLN B OE1 1 
ATOM 1908 N NE2 . GLN B 1 127 ? 266.298 315.318 401.473 1.00 87.10  ? 127 GLN B NE2 1 
ATOM 1909 N N   . LEU B 1 128 ? 265.476 312.282 395.348 1.00 75.82  ? 128 LEU B N   1 
ATOM 1910 C CA  . LEU B 1 128 ? 265.671 311.492 394.134 1.00 75.82  ? 128 LEU B CA  1 
ATOM 1911 C C   . LEU B 1 128 ? 266.620 310.318 394.353 1.00 75.82  ? 128 LEU B C   1 
ATOM 1912 O O   . LEU B 1 128 ? 267.312 309.890 393.428 1.00 75.82  ? 128 LEU B O   1 
ATOM 1913 C CB  . LEU B 1 128 ? 266.172 312.355 392.974 1.00 75.82  ? 128 LEU B CB  1 
ATOM 1914 C CG  . LEU B 1 128 ? 265.164 313.326 392.362 1.00 75.82  ? 128 LEU B CG  1 
ATOM 1915 C CD1 . LEU B 1 128 ? 265.160 314.648 393.111 1.00 75.82  ? 128 LEU B CD1 1 
ATOM 1916 C CD2 . LEU B 1 128 ? 265.433 313.529 390.889 1.00 75.82  ? 128 LEU B CD2 1 
ATOM 1917 N N   . ASN B 1 129 ? 266.665 309.785 395.564 1.00 75.13  ? 129 ASN B N   1 
ATOM 1918 C CA  . ASN B 1 129 ? 267.475 308.600 395.811 1.00 75.13  ? 129 ASN B CA  1 
ATOM 1919 C C   . ASN B 1 129 ? 266.794 307.392 395.184 1.00 75.13  ? 129 ASN B C   1 
ATOM 1920 O O   . ASN B 1 129 ? 265.659 307.073 395.559 1.00 75.13  ? 129 ASN B O   1 
ATOM 1921 C CB  . ASN B 1 129 ? 267.670 308.376 397.306 1.00 75.13  ? 129 ASN B CB  1 
ATOM 1922 C CG  . ASN B 1 129 ? 268.438 309.497 397.969 1.00 75.13  ? 129 ASN B CG  1 
ATOM 1923 O OD1 . ASN B 1 129 ? 267.903 310.219 398.809 1.00 75.13  ? 129 ASN B OD1 1 
ATOM 1924 N ND2 . ASN B 1 129 ? 269.703 309.650 397.595 1.00 75.13  ? 129 ASN B ND2 1 
ATOM 1925 N N   . PRO B 1 130 ? 267.427 306.703 394.239 1.00 64.22  ? 130 PRO B N   1 
ATOM 1926 C CA  . PRO B 1 130 ? 266.803 305.506 393.667 1.00 64.22  ? 130 PRO B CA  1 
ATOM 1927 C C   . PRO B 1 130 ? 266.596 304.442 394.732 1.00 64.22  ? 130 PRO B C   1 
ATOM 1928 O O   . PRO B 1 130 ? 267.360 304.334 395.692 1.00 64.22  ? 130 PRO B O   1 
ATOM 1929 C CB  . PRO B 1 130 ? 267.809 305.049 392.603 1.00 64.22  ? 130 PRO B CB  1 
ATOM 1930 C CG  . PRO B 1 130 ? 269.092 305.718 392.965 1.00 64.22  ? 130 PRO B CG  1 
ATOM 1931 C CD  . PRO B 1 130 ? 268.718 307.013 393.608 1.00 64.22  ? 130 PRO B CD  1 
ATOM 1932 N N   . ALA B 1 131 ? 265.537 303.661 394.559 1.00 59.83  ? 131 ALA B N   1 
ATOM 1933 C CA  . ALA B 1 131 ? 265.201 302.618 395.518 1.00 59.83  ? 131 ALA B CA  1 
ATOM 1934 C C   . ALA B 1 131 ? 266.264 301.523 395.534 1.00 59.83  ? 131 ALA B C   1 
ATOM 1935 O O   . ALA B 1 131 ? 267.155 301.520 396.384 1.00 59.83  ? 131 ALA B O   1 
ATOM 1936 C CB  . ALA B 1 131 ? 263.840 302.032 395.201 1.00 59.83  ? 131 ALA B CB  1 
ATOM 1937 N N   . ILE C 2 1   ? 276.830 313.699 423.395 1.00 172.34 ? 5   ILE L N   1 
ATOM 1938 C CA  . ILE C 2 1   ? 277.257 314.744 422.473 1.00 172.34 ? 5   ILE L CA  1 
ATOM 1939 C C   . ILE C 2 1   ? 276.922 316.101 423.078 1.00 172.34 ? 5   ILE L C   1 
ATOM 1940 O O   . ILE C 2 1   ? 276.240 316.917 422.462 1.00 172.34 ? 5   ILE L O   1 
ATOM 1941 C CB  . ILE C 2 1   ? 276.603 314.573 421.091 1.00 172.34 ? 5   ILE L CB  1 
ATOM 1942 C CG1 . ILE C 2 1   ? 276.462 313.089 420.743 1.00 172.34 ? 5   ILE L CG1 1 
ATOM 1943 C CG2 . ILE C 2 1   ? 277.421 315.282 420.023 1.00 172.34 ? 5   ILE L CG2 1 
ATOM 1944 C CD1 . ILE C 2 1   ? 277.779 312.348 420.642 1.00 172.34 ? 5   ILE L CD1 1 
ATOM 1945 N N   . GLN C 2 2   ? 277.406 316.332 424.295 1.00 174.47 ? 6   GLN L N   1 
ATOM 1946 C CA  . GLN C 2 2   ? 277.041 317.526 425.042 1.00 174.47 ? 6   GLN L CA  1 
ATOM 1947 C C   . GLN C 2 2   ? 277.665 318.779 424.439 1.00 174.47 ? 6   GLN L C   1 
ATOM 1948 O O   . GLN C 2 2   ? 278.724 318.737 423.807 1.00 174.47 ? 6   GLN L O   1 
ATOM 1949 C CB  . GLN C 2 2   ? 277.472 317.395 426.503 1.00 174.47 ? 6   GLN L CB  1 
ATOM 1950 C CG  . GLN C 2 2   ? 276.632 316.433 427.323 1.00 174.47 ? 6   GLN L CG  1 
ATOM 1951 C CD  . GLN C 2 2   ? 276.983 316.473 428.797 1.00 174.47 ? 6   GLN L CD  1 
ATOM 1952 O OE1 . GLN C 2 2   ? 277.899 317.185 429.208 1.00 174.47 ? 6   GLN L OE1 1 
ATOM 1953 N NE2 . GLN C 2 2   ? 276.254 315.709 429.601 1.00 174.47 ? 6   GLN L NE2 1 
ATOM 1954 N N   . MET C 2 3   ? 276.987 319.903 424.640 1.00 176.05 ? 7   MET L N   1 
ATOM 1955 C CA  . MET C 2 3   ? 277.512 321.227 424.346 1.00 176.05 ? 7   MET L CA  1 
ATOM 1956 C C   . MET C 2 3   ? 277.644 322.018 425.640 1.00 176.05 ? 7   MET L C   1 
ATOM 1957 O O   . MET C 2 3   ? 277.106 321.643 426.685 1.00 176.05 ? 7   MET L O   1 
ATOM 1958 C CB  . MET C 2 3   ? 276.611 321.975 423.357 1.00 176.05 ? 7   MET L CB  1 
ATOM 1959 C CG  . MET C 2 3   ? 276.747 321.524 421.916 1.00 176.05 ? 7   MET L CG  1 
ATOM 1960 S SD  . MET C 2 3   ? 275.986 319.918 421.637 1.00 176.05 ? 7   MET L SD  1 
ATOM 1961 C CE  . MET C 2 3   ? 274.254 320.369 421.680 1.00 176.05 ? 7   MET L CE  1 
ATOM 1962 N N   . THR C 2 4   ? 278.370 323.130 425.562 1.00 175.69 ? 8   THR L N   1 
ATOM 1963 C CA  . THR C 2 4   ? 278.569 324.005 426.706 1.00 175.69 ? 8   THR L CA  1 
ATOM 1964 C C   . THR C 2 4   ? 278.254 325.441 426.315 1.00 175.69 ? 8   THR L C   1 
ATOM 1965 O O   . THR C 2 4   ? 278.442 325.846 425.164 1.00 175.69 ? 8   THR L O   1 
ATOM 1966 C CB  . THR C 2 4   ? 280.003 323.921 427.252 1.00 175.69 ? 8   THR L CB  1 
ATOM 1967 O OG1 . THR C 2 4   ? 280.928 324.336 426.240 1.00 175.69 ? 8   THR L OG1 1 
ATOM 1968 C CG2 . THR C 2 4   ? 280.333 322.500 427.684 1.00 175.69 ? 8   THR L CG2 1 
ATOM 1969 N N   . GLN C 2 5   ? 277.769 326.207 427.289 1.00 172.31 ? 9   GLN L N   1 
ATOM 1970 C CA  . GLN C 2 5   ? 277.422 327.602 427.069 1.00 172.31 ? 9   GLN L CA  1 
ATOM 1971 C C   . GLN C 2 5   ? 277.712 328.391 428.336 1.00 172.31 ? 9   GLN L C   1 
ATOM 1972 O O   . GLN C 2 5   ? 277.717 327.846 429.443 1.00 172.31 ? 9   GLN L O   1 
ATOM 1973 C CB  . GLN C 2 5   ? 275.955 327.754 426.651 1.00 172.31 ? 9   GLN L CB  1 
ATOM 1974 C CG  . GLN C 2 5   ? 274.947 327.345 427.706 1.00 172.31 ? 9   GLN L CG  1 
ATOM 1975 C CD  . GLN C 2 5   ? 273.518 327.461 427.211 1.00 172.31 ? 9   GLN L CD  1 
ATOM 1976 O OE1 . GLN C 2 5   ? 272.574 327.119 427.922 1.00 172.31 ? 9   GLN L OE1 1 
ATOM 1977 N NE2 . GLN C 2 5   ? 273.352 327.952 425.990 1.00 172.31 ? 9   GLN L NE2 1 
ATOM 1978 N N   . SER C 2 6   ? 277.957 329.684 428.160 1.00 171.23 ? 10  SER L N   1 
ATOM 1979 C CA  . SER C 2 6   ? 278.315 330.543 429.282 1.00 171.23 ? 10  SER L CA  1 
ATOM 1980 C C   . SER C 2 6   ? 277.078 330.859 430.111 1.00 171.23 ? 10  SER L C   1 
ATOM 1981 O O   . SER C 2 6   ? 276.131 331.456 429.588 1.00 171.23 ? 10  SER L O   1 
ATOM 1982 C CB  . SER C 2 6   ? 278.953 331.833 428.784 1.00 171.23 ? 10  SER L CB  1 
ATOM 1983 O OG  . SER C 2 6   ? 277.999 332.652 428.131 1.00 171.23 ? 10  SER L OG  1 
ATOM 1984 N N   . PRO C 2 7   ? 277.041 330.491 431.386 1.00 171.76 ? 11  PRO L N   1 
ATOM 1985 C CA  . PRO C 2 7   ? 275.868 330.764 432.215 1.00 171.76 ? 11  PRO L CA  1 
ATOM 1986 C C   . PRO C 2 7   ? 275.997 332.081 432.974 1.00 171.76 ? 11  PRO L C   1 
ATOM 1987 O O   . PRO C 2 7   ? 277.040 332.736 432.970 1.00 171.76 ? 11  PRO L O   1 
ATOM 1988 C CB  . PRO C 2 7   ? 275.861 329.576 433.183 1.00 171.76 ? 11  PRO L CB  1 
ATOM 1989 C CG  . PRO C 2 7   ? 277.317 329.280 433.381 1.00 171.76 ? 11  PRO L CG  1 
ATOM 1990 C CD  . PRO C 2 7   ? 278.026 329.651 432.091 1.00 171.76 ? 11  PRO L CD  1 
ATOM 1991 N N   . SER C 2 8   ? 274.897 332.452 433.631 1.00 173.33 ? 12  SER L N   1 
ATOM 1992 C CA  . SER C 2 8   ? 274.835 333.615 434.515 1.00 173.33 ? 12  SER L CA  1 
ATOM 1993 C C   . SER C 2 8   ? 275.228 334.899 433.780 1.00 173.33 ? 12  SER L C   1 
ATOM 1994 O O   . SER C 2 8   ? 276.201 335.574 434.121 1.00 173.33 ? 12  SER L O   1 
ATOM 1995 C CB  . SER C 2 8   ? 275.707 333.402 435.758 1.00 173.33 ? 12  SER L CB  1 
ATOM 1996 O OG  . SER C 2 8   ? 275.627 334.514 436.631 1.00 173.33 ? 12  SER L OG  1 
ATOM 1997 N N   . SER C 2 9   ? 274.446 335.225 432.749 1.00 172.85 ? 13  SER L N   1 
ATOM 1998 C CA  . SER C 2 9   ? 274.633 336.492 432.050 1.00 172.85 ? 13  SER L CA  1 
ATOM 1999 C C   . SER C 2 9   ? 274.368 337.667 432.984 1.00 172.85 ? 13  SER L C   1 
ATOM 2000 O O   . SER C 2 9   ? 275.267 338.465 433.273 1.00 172.85 ? 13  SER L O   1 
ATOM 2001 C CB  . SER C 2 9   ? 273.720 336.553 430.825 1.00 172.85 ? 13  SER L CB  1 
ATOM 2002 O OG  . SER C 2 9   ? 272.355 336.559 431.206 1.00 172.85 ? 13  SER L OG  1 
ATOM 2003 N N   . LEU C 2 10  ? 273.130 337.779 433.472 1.00 176.90 ? 14  LEU L N   1 
ATOM 2004 C CA  . LEU C 2 10  ? 272.739 338.783 434.463 1.00 176.90 ? 14  LEU L CA  1 
ATOM 2005 C C   . LEU C 2 10  ? 273.100 340.200 434.023 1.00 176.90 ? 14  LEU L C   1 
ATOM 2006 O O   . LEU C 2 10  ? 273.545 341.019 434.830 1.00 176.90 ? 14  LEU L O   1 
ATOM 2007 C CB  . LEU C 2 10  ? 273.354 338.477 435.832 1.00 176.90 ? 14  LEU L CB  1 
ATOM 2008 C CG  . LEU C 2 10  ? 272.651 337.388 436.648 1.00 176.90 ? 14  LEU L CG  1 
ATOM 2009 C CD1 . LEU C 2 10  ? 273.417 337.089 437.927 1.00 176.90 ? 14  LEU L CD1 1 
ATOM 2010 C CD2 . LEU C 2 10  ? 271.219 337.794 436.960 1.00 176.90 ? 14  LEU L CD2 1 
ATOM 2011 N N   . SER C 2 11  ? 272.909 340.500 432.742 1.00 180.33 ? 15  SER L N   1 
ATOM 2012 C CA  . SER C 2 11  ? 273.197 341.828 432.208 1.00 180.33 ? 15  SER L CA  1 
ATOM 2013 C C   . SER C 2 11  ? 271.961 342.699 432.387 1.00 180.33 ? 15  SER L C   1 
ATOM 2014 O O   . SER C 2 11  ? 270.976 342.558 431.660 1.00 180.33 ? 15  SER L O   1 
ATOM 2015 C CB  . SER C 2 11  ? 273.608 341.740 430.743 1.00 180.33 ? 15  SER L CB  1 
ATOM 2016 O OG  . SER C 2 11  ? 274.845 341.064 430.601 1.00 180.33 ? 15  SER L OG  1 
ATOM 2017 N N   . ALA C 2 12  ? 272.007 343.601 433.363 1.00 178.94 ? 16  ALA L N   1 
ATOM 2018 C CA  . ALA C 2 12  ? 270.903 344.515 433.626 1.00 178.94 ? 16  ALA L CA  1 
ATOM 2019 C C   . ALA C 2 12  ? 270.934 345.753 432.739 1.00 178.94 ? 16  ALA L C   1 
ATOM 2020 O O   . ALA C 2 12  ? 270.011 346.572 432.810 1.00 178.94 ? 16  ALA L O   1 
ATOM 2021 C CB  . ALA C 2 12  ? 270.906 344.933 435.100 1.00 178.94 ? 16  ALA L CB  1 
ATOM 2022 N N   . SER C 2 13  ? 271.963 345.907 431.910 1.00 180.82 ? 17  SER L N   1 
ATOM 2023 C CA  . SER C 2 13  ? 272.084 347.071 431.048 1.00 180.82 ? 17  SER L CA  1 
ATOM 2024 C C   . SER C 2 13  ? 271.184 346.924 429.822 1.00 180.82 ? 17  SER L C   1 
ATOM 2025 O O   . SER C 2 13  ? 270.667 345.846 429.517 1.00 180.82 ? 17  SER L O   1 
ATOM 2026 C CB  . SER C 2 13  ? 273.539 347.274 430.635 1.00 180.82 ? 17  SER L CB  1 
ATOM 2027 O OG  . SER C 2 13  ? 273.646 348.255 429.618 1.00 180.82 ? 17  SER L OG  1 
ATOM 2028 N N   . LEU C 2 14  ? 270.997 348.033 429.105 1.00 184.40 ? 18  LEU L N   1 
ATOM 2029 C CA  . LEU C 2 14  ? 270.203 348.050 427.881 1.00 184.40 ? 18  LEU L CA  1 
ATOM 2030 C C   . LEU C 2 14  ? 271.066 347.774 426.654 1.00 184.40 ? 18  LEU L C   1 
ATOM 2031 O O   . LEU C 2 14  ? 270.749 346.893 425.851 1.00 184.40 ? 18  LEU L O   1 
ATOM 2032 C CB  . LEU C 2 14  ? 269.476 349.396 427.747 1.00 184.40 ? 18  LEU L CB  1 
ATOM 2033 C CG  . LEU C 2 14  ? 268.378 349.520 426.686 1.00 184.40 ? 18  LEU L CG  1 
ATOM 2034 C CD1 . LEU C 2 14  ? 267.260 350.420 427.190 1.00 184.40 ? 18  LEU L CD1 1 
ATOM 2035 C CD2 . LEU C 2 14  ? 268.933 350.048 425.371 1.00 184.40 ? 18  LEU L CD2 1 
ATOM 2036 N N   . GLY C 2 15  ? 272.158 348.515 426.494 1.00 186.97 ? 19  GLY L N   1 
ATOM 2037 C CA  . GLY C 2 15  ? 273.077 348.252 425.406 1.00 186.97 ? 19  GLY L CA  1 
ATOM 2038 C C   . GLY C 2 15  ? 274.036 347.134 425.750 1.00 186.97 ? 19  GLY L C   1 
ATOM 2039 O O   . GLY C 2 15  ? 274.971 347.328 426.532 1.00 186.97 ? 19  GLY L O   1 
ATOM 2040 N N   . GLU C 2 16  ? 273.816 345.955 425.173 1.00 188.76 ? 20  GLU L N   1 
ATOM 2041 C CA  . GLU C 2 16  ? 274.584 344.771 425.519 1.00 188.76 ? 20  GLU L CA  1 
ATOM 2042 C C   . GLU C 2 16  ? 275.026 344.042 424.260 1.00 188.76 ? 20  GLU L C   1 
ATOM 2043 O O   . GLU C 2 16  ? 274.298 343.983 423.265 1.00 188.76 ? 20  GLU L O   1 
ATOM 2044 C CB  . GLU C 2 16  ? 273.770 343.822 426.410 1.00 188.76 ? 20  GLU L CB  1 
ATOM 2045 C CG  . GLU C 2 16  ? 273.715 344.232 427.872 1.00 188.76 ? 20  GLU L CG  1 
ATOM 2046 C CD  . GLU C 2 16  ? 275.037 344.031 428.581 1.00 188.76 ? 20  GLU L CD  1 
ATOM 2047 O OE1 . GLU C 2 16  ? 275.785 343.111 428.190 1.00 188.76 ? 20  GLU L OE1 1 
ATOM 2048 O OE2 . GLU C 2 16  ? 275.326 344.788 429.531 1.00 188.76 ? 20  GLU L OE2 1 
ATOM 2049 N N   . ARG C 2 17  ? 276.236 343.492 424.319 1.00 189.19 ? 21  ARG L N   1 
ATOM 2050 C CA  . ARG C 2 17  ? 276.805 342.640 423.279 1.00 189.19 ? 21  ARG L CA  1 
ATOM 2051 C C   . ARG C 2 17  ? 277.439 341.406 423.910 1.00 189.19 ? 21  ARG L C   1 
ATOM 2052 O O   . ARG C 2 17  ? 278.544 340.989 423.559 1.00 189.19 ? 21  ARG L O   1 
ATOM 2053 C CB  . ARG C 2 17  ? 277.825 343.411 422.445 1.00 189.19 ? 21  ARG L CB  1 
ATOM 2054 C CG  . ARG C 2 17  ? 277.240 344.555 421.632 1.00 189.19 ? 21  ARG L CG  1 
ATOM 2055 C CD  . ARG C 2 17  ? 276.286 344.051 420.563 1.00 189.19 ? 21  ARG L CD  1 
ATOM 2056 N NE  . ARG C 2 17  ? 275.744 345.143 419.764 1.00 189.19 ? 21  ARG L NE  1 
ATOM 2057 C CZ  . ARG C 2 17  ? 276.258 345.549 418.612 1.00 189.19 ? 21  ARG L CZ  1 
ATOM 2058 N NH1 . ARG C 2 17  ? 277.326 344.969 418.089 1.00 189.19 ? 21  ARG L NH1 1 
ATOM 2059 N NH2 . ARG C 2 17  ? 275.689 346.565 417.969 1.00 189.19 ? 21  ARG L NH2 1 
ATOM 2060 N N   . VAL C 2 18  ? 276.727 340.804 424.868 1.00 187.82 ? 22  VAL L N   1 
ATOM 2061 C CA  . VAL C 2 18  ? 277.281 339.681 425.621 1.00 187.82 ? 22  VAL L CA  1 
ATOM 2062 C C   . VAL C 2 18  ? 277.511 338.479 424.711 1.00 187.82 ? 22  VAL L C   1 
ATOM 2063 O O   . VAL C 2 18  ? 278.501 337.752 424.863 1.00 187.82 ? 22  VAL L O   1 
ATOM 2064 C CB  . VAL C 2 18  ? 276.372 339.341 426.818 1.00 187.82 ? 22  VAL L CB  1 
ATOM 2065 C CG1 . VAL C 2 18  ? 274.989 338.919 426.349 1.00 187.82 ? 22  VAL L CG1 1 
ATOM 2066 C CG2 . VAL C 2 18  ? 277.005 338.259 427.679 1.00 187.82 ? 22  VAL L CG2 1 
ATOM 2067 N N   . SER C 2 19  ? 276.612 338.255 423.749 1.00 184.95 ? 23  SER L N   1 
ATOM 2068 C CA  . SER C 2 19  ? 276.789 337.243 422.707 1.00 184.95 ? 23  SER L CA  1 
ATOM 2069 C C   . SER C 2 19  ? 276.990 335.847 423.304 1.00 184.95 ? 23  SER L C   1 
ATOM 2070 O O   . SER C 2 19  ? 278.094 335.300 423.323 1.00 184.95 ? 23  SER L O   1 
ATOM 2071 C CB  . SER C 2 19  ? 277.947 337.617 421.777 1.00 184.95 ? 23  SER L CB  1 
ATOM 2072 O OG  . SER C 2 19  ? 277.733 338.890 421.194 1.00 184.95 ? 23  SER L OG  1 
ATOM 2073 N N   . LEU C 2 20  ? 275.893 335.285 423.809 1.00 184.29 ? 24  LEU L N   1 
ATOM 2074 C CA  . LEU C 2 20  ? 275.918 333.933 424.357 1.00 184.29 ? 24  LEU L CA  1 
ATOM 2075 C C   . LEU C 2 20  ? 276.445 332.945 423.324 1.00 184.29 ? 24  LEU L C   1 
ATOM 2076 O O   . LEU C 2 20  ? 276.026 332.957 422.164 1.00 184.29 ? 24  LEU L O   1 
ATOM 2077 C CB  . LEU C 2 20  ? 274.516 333.517 424.811 1.00 184.29 ? 24  LEU L CB  1 
ATOM 2078 C CG  . LEU C 2 20  ? 274.001 333.941 426.189 1.00 184.29 ? 24  LEU L CG  1 
ATOM 2079 C CD1 . LEU C 2 20  ? 274.855 333.309 427.277 1.00 184.29 ? 24  LEU L CD1 1 
ATOM 2080 C CD2 . LEU C 2 20  ? 273.954 335.452 426.339 1.00 184.29 ? 24  LEU L CD2 1 
ATOM 2081 N N   . THR C 2 21  ? 277.366 332.088 423.754 1.00 183.20 ? 25  THR L N   1 
ATOM 2082 C CA  . THR C 2 21  ? 278.020 331.131 422.877 1.00 183.20 ? 25  THR L CA  1 
ATOM 2083 C C   . THR C 2 21  ? 277.630 329.708 423.251 1.00 183.20 ? 25  THR L C   1 
ATOM 2084 O O   . THR C 2 21  ? 277.351 329.406 424.414 1.00 183.20 ? 25  THR L O   1 
ATOM 2085 C CB  . THR C 2 21  ? 279.545 331.283 422.932 1.00 183.20 ? 25  THR L CB  1 
ATOM 2086 O OG1 . THR C 2 21  ? 280.151 330.446 421.937 1.00 183.20 ? 25  THR L OG1 1 
ATOM 2087 C CG2 . THR C 2 21  ? 280.077 330.901 424.307 1.00 183.20 ? 25  THR L CG2 1 
ATOM 2088 N N   . CYS C 2 22  ? 277.601 328.838 422.244 1.00 184.73 ? 26  CYS L N   1 
ATOM 2089 C CA  . CYS C 2 22  ? 277.309 327.421 422.426 1.00 184.73 ? 26  CYS L CA  1 
ATOM 2090 C C   . CYS C 2 22  ? 278.436 326.624 421.787 1.00 184.73 ? 26  CYS L C   1 
ATOM 2091 O O   . CYS C 2 22  ? 278.562 326.601 420.559 1.00 184.73 ? 26  CYS L O   1 
ATOM 2092 C CB  . CYS C 2 22  ? 275.954 327.052 421.811 1.00 184.73 ? 26  CYS L CB  1 
ATOM 2093 S SG  . CYS C 2 22  ? 275.253 325.475 422.366 1.00 184.73 ? 26  CYS L SG  1 
ATOM 2094 N N   . ARG C 2 23  ? 279.252 325.980 422.617 1.00 184.59 ? 27  ARG L N   1 
ATOM 2095 C CA  . ARG C 2 23  ? 280.437 325.268 422.154 1.00 184.59 ? 27  ARG L CA  1 
ATOM 2096 C C   . ARG C 2 23  ? 280.052 323.856 421.730 1.00 184.59 ? 27  ARG L C   1 
ATOM 2097 O O   . ARG C 2 23  ? 279.612 323.052 422.558 1.00 184.59 ? 27  ARG L O   1 
ATOM 2098 C CB  . ARG C 2 23  ? 281.497 325.226 423.253 1.00 184.59 ? 27  ARG L CB  1 
ATOM 2099 C CG  . ARG C 2 23  ? 282.695 324.339 422.947 1.00 184.59 ? 27  ARG L CG  1 
ATOM 2100 C CD  . ARG C 2 23  ? 283.409 324.774 421.679 1.00 184.59 ? 27  ARG L CD  1 
ATOM 2101 N NE  . ARG C 2 23  ? 283.987 326.106 421.813 1.00 184.59 ? 27  ARG L NE  1 
ATOM 2102 C CZ  . ARG C 2 23  ? 285.091 326.509 421.199 1.00 184.59 ? 27  ARG L CZ  1 
ATOM 2103 N NH1 . ARG C 2 23  ? 285.767 325.706 420.394 1.00 184.59 ? 27  ARG L NH1 1 
ATOM 2104 N NH2 . ARG C 2 23  ? 285.527 327.750 421.396 1.00 184.59 ? 27  ARG L NH2 1 
ATOM 2105 N N   . ALA C 2 24  ? 280.226 323.555 420.446 1.00 183.34 ? 28  ALA L N   1 
ATOM 2106 C CA  . ALA C 2 24  ? 279.915 322.231 419.927 1.00 183.34 ? 28  ALA L CA  1 
ATOM 2107 C C   . ALA C 2 24  ? 281.074 321.278 420.192 1.00 183.34 ? 28  ALA L C   1 
ATOM 2108 O O   . ALA C 2 24  ? 282.229 321.591 419.885 1.00 183.34 ? 28  ALA L O   1 
ATOM 2109 C CB  . ALA C 2 24  ? 279.618 322.300 418.430 1.00 183.34 ? 28  ALA L CB  1 
ATOM 2110 N N   . SER C 2 25  ? 280.764 320.111 420.758 1.00 180.42 ? 29  SER L N   1 
ATOM 2111 C CA  . SER C 2 25  ? 281.796 319.119 421.042 1.00 180.42 ? 29  SER L CA  1 
ATOM 2112 C C   . SER C 2 25  ? 282.269 318.441 419.761 1.00 180.42 ? 29  SER L C   1 
ATOM 2113 O O   . SER C 2 25  ? 283.454 318.493 419.418 1.00 180.42 ? 29  SER L O   1 
ATOM 2114 C CB  . SER C 2 25  ? 281.270 318.083 422.037 1.00 180.42 ? 29  SER L CB  1 
ATOM 2115 O OG  . SER C 2 25  ? 280.947 318.687 423.277 1.00 180.42 ? 29  SER L OG  1 
ATOM 2116 N N   . GLN C 2 26  ? 281.352 317.798 419.046 1.00 183.75 ? 30  GLN L N   1 
ATOM 2117 C CA  . GLN C 2 26  ? 281.687 317.218 417.757 1.00 183.75 ? 30  GLN L CA  1 
ATOM 2118 C C   . GLN C 2 26  ? 281.938 318.318 416.731 1.00 183.75 ? 30  GLN L C   1 
ATOM 2119 O O   . GLN C 2 26  ? 281.543 319.475 416.906 1.00 183.75 ? 30  GLN L O   1 
ATOM 2120 C CB  . GLN C 2 26  ? 280.572 316.290 417.277 1.00 183.75 ? 30  GLN L CB  1 
ATOM 2121 C CG  . GLN C 2 26  ? 280.564 314.931 417.954 1.00 183.75 ? 30  GLN L CG  1 
ATOM 2122 C CD  . GLN C 2 26  ? 279.461 314.031 417.435 1.00 183.75 ? 30  GLN L CD  1 
ATOM 2123 O OE1 . GLN C 2 26  ? 278.579 314.472 416.699 1.00 183.75 ? 30  GLN L OE1 1 
ATOM 2124 N NE2 . GLN C 2 26  ? 279.508 312.759 417.812 1.00 183.75 ? 30  GLN L NE2 1 
ATOM 2125 N N   . ASP C 2 27  ? 282.609 317.942 415.644 1.00 194.56 ? 31  ASP L N   1 
ATOM 2126 C CA  . ASP C 2 27  ? 283.041 318.886 414.624 1.00 194.56 ? 31  ASP L CA  1 
ATOM 2127 C C   . ASP C 2 27  ? 282.061 318.957 413.453 1.00 194.56 ? 31  ASP L C   1 
ATOM 2128 O O   . ASP C 2 27  ? 282.355 319.594 412.436 1.00 194.56 ? 31  ASP L O   1 
ATOM 2129 C CB  . ASP C 2 27  ? 284.448 318.510 414.148 1.00 194.56 ? 31  ASP L CB  1 
ATOM 2130 C CG  . ASP C 2 27  ? 285.060 319.546 413.223 1.00 194.56 ? 31  ASP L CG  1 
ATOM 2131 O OD1 . ASP C 2 27  ? 285.464 320.620 413.718 1.00 194.56 ? 31  ASP L OD1 1 
ATOM 2132 O OD2 . ASP C 2 27  ? 285.144 319.284 412.005 1.00 194.56 ? 31  ASP L OD2 1 
ATOM 2133 N N   . ILE C 2 28  ? 280.889 318.337 413.585 1.00 183.53 ? 32  ILE L N   1 
ATOM 2134 C CA  . ILE C 2 28  ? 279.928 318.292 412.489 1.00 183.53 ? 32  ILE L CA  1 
ATOM 2135 C C   . ILE C 2 28  ? 279.091 319.565 412.482 1.00 183.53 ? 32  ILE L C   1 
ATOM 2136 O O   . ILE C 2 28  ? 279.166 320.360 411.539 1.00 183.53 ? 32  ILE L O   1 
ATOM 2137 C CB  . ILE C 2 28  ? 279.029 317.045 412.585 1.00 183.53 ? 32  ILE L CB  1 
ATOM 2138 C CG1 . ILE C 2 28  ? 279.855 315.769 412.395 1.00 183.53 ? 32  ILE L CG1 1 
ATOM 2139 C CG2 . ILE C 2 28  ? 277.909 317.118 411.557 1.00 183.53 ? 32  ILE L CG2 1 
ATOM 2140 C CD1 . ILE C 2 28  ? 280.393 315.176 413.685 1.00 183.53 ? 32  ILE L CD1 1 
ATOM 2141 N N   . GLY C 2 29  ? 278.305 319.772 413.537 1.00 179.99 ? 33  GLY L N   1 
ATOM 2142 C CA  . GLY C 2 29  ? 277.484 320.969 413.626 1.00 179.99 ? 33  GLY L CA  1 
ATOM 2143 C C   . GLY C 2 29  ? 276.548 321.111 412.443 1.00 179.99 ? 33  GLY L C   1 
ATOM 2144 O O   . GLY C 2 29  ? 275.851 320.169 412.049 1.00 179.99 ? 33  GLY L O   1 
ATOM 2145 N N   . SER C 2 30  ? 276.528 322.315 411.869 1.00 181.88 ? 34  SER L N   1 
ATOM 2146 C CA  . SER C 2 30  ? 275.763 322.704 410.686 1.00 181.88 ? 34  SER L CA  1 
ATOM 2147 C C   . SER C 2 30  ? 274.257 322.697 410.911 1.00 181.88 ? 34  SER L C   1 
ATOM 2148 O O   . SER C 2 30  ? 273.505 322.908 409.951 1.00 181.88 ? 34  SER L O   1 
ATOM 2149 C CB  . SER C 2 30  ? 276.083 321.826 409.467 1.00 181.88 ? 34  SER L CB  1 
ATOM 2150 O OG  . SER C 2 30  ? 277.437 321.968 409.078 1.00 181.88 ? 34  SER L OG  1 
ATOM 2151 N N   . SER C 2 31  ? 273.785 322.464 412.137 1.00 176.40 ? 35  SER L N   1 
ATOM 2152 C CA  . SER C 2 31  ? 272.349 322.467 412.412 1.00 176.40 ? 35  SER L CA  1 
ATOM 2153 C C   . SER C 2 31  ? 272.170 322.768 413.900 1.00 176.40 ? 35  SER L C   1 
ATOM 2154 O O   . SER C 2 31  ? 272.344 321.878 414.736 1.00 176.40 ? 35  SER L O   1 
ATOM 2155 C CB  . SER C 2 31  ? 271.715 321.141 412.028 1.00 176.40 ? 35  SER L CB  1 
ATOM 2156 O OG  . SER C 2 31  ? 271.694 320.974 410.622 1.00 176.40 ? 35  SER L OG  1 
ATOM 2157 N N   . LEU C 2 32  ? 271.818 324.013 414.213 1.00 172.52 ? 36  LEU L N   1 
ATOM 2158 C CA  . LEU C 2 32  ? 271.701 324.464 415.590 1.00 172.52 ? 36  LEU L CA  1 
ATOM 2159 C C   . LEU C 2 32  ? 270.390 325.212 415.781 1.00 172.52 ? 36  LEU L C   1 
ATOM 2160 O O   . LEU C 2 32  ? 269.943 325.951 414.900 1.00 172.52 ? 36  LEU L O   1 
ATOM 2161 C CB  . LEU C 2 32  ? 272.879 325.367 415.978 1.00 172.52 ? 36  LEU L CB  1 
ATOM 2162 C CG  . LEU C 2 32  ? 272.940 325.875 417.419 1.00 172.52 ? 36  LEU L CG  1 
ATOM 2163 C CD1 . LEU C 2 32  ? 273.080 324.719 418.391 1.00 172.52 ? 36  LEU L CD1 1 
ATOM 2164 C CD2 . LEU C 2 32  ? 274.087 326.850 417.586 1.00 172.52 ? 36  LEU L CD2 1 
ATOM 2165 N N   . ASN C 2 33  ? 269.778 325.014 416.946 1.00 170.09 ? 37  ASN L N   1 
ATOM 2166 C CA  . ASN C 2 33  ? 268.532 325.673 417.307 1.00 170.09 ? 37  ASN L CA  1 
ATOM 2167 C C   . ASN C 2 33  ? 268.720 326.416 418.619 1.00 170.09 ? 37  ASN L C   1 
ATOM 2168 O O   . ASN C 2 33  ? 269.430 325.944 419.512 1.00 170.09 ? 37  ASN L O   1 
ATOM 2169 C CB  . ASN C 2 33  ? 267.382 324.669 417.447 1.00 170.09 ? 37  ASN L CB  1 
ATOM 2170 C CG  . ASN C 2 33  ? 266.803 324.257 416.113 1.00 170.09 ? 37  ASN L CG  1 
ATOM 2171 O OD1 . ASN C 2 33  ? 265.795 323.554 416.050 1.00 170.09 ? 37  ASN L OD1 1 
ATOM 2172 N ND2 . ASN C 2 33  ? 267.443 324.686 415.035 1.00 170.09 ? 37  ASN L ND2 1 
ATOM 2173 N N   . TRP C 2 34  ? 268.084 327.579 418.734 1.00 173.43 ? 38  TRP L N   1 
ATOM 2174 C CA  . TRP C 2 34  ? 268.146 328.384 419.945 1.00 173.43 ? 38  TRP L CA  1 
ATOM 2175 C C   . TRP C 2 34  ? 266.748 328.547 420.521 1.00 173.43 ? 38  TRP L C   1 
ATOM 2176 O O   . TRP C 2 34  ? 265.822 328.955 419.813 1.00 173.43 ? 38  TRP L O   1 
ATOM 2177 C CB  . TRP C 2 34  ? 268.776 329.751 419.675 1.00 173.43 ? 38  TRP L CB  1 
ATOM 2178 C CG  . TRP C 2 34  ? 270.191 329.661 419.207 1.00 173.43 ? 38  TRP L CG  1 
ATOM 2179 C CD1 . TRP C 2 34  ? 270.620 329.347 417.953 1.00 173.43 ? 38  TRP L CD1 1 
ATOM 2180 C CD2 . TRP C 2 34  ? 271.370 329.851 419.999 1.00 173.43 ? 38  TRP L CD2 1 
ATOM 2181 N NE1 . TRP C 2 34  ? 271.992 329.351 417.907 1.00 173.43 ? 38  TRP L NE1 1 
ATOM 2182 C CE2 . TRP C 2 34  ? 272.477 329.655 419.152 1.00 173.43 ? 38  TRP L CE2 1 
ATOM 2183 C CE3 . TRP C 2 34  ? 271.596 330.176 421.340 1.00 173.43 ? 38  TRP L CE3 1 
ATOM 2184 C CZ2 . TRP C 2 34  ? 273.790 329.773 419.601 1.00 173.43 ? 38  TRP L CZ2 1 
ATOM 2185 C CZ3 . TRP C 2 34  ? 272.900 330.291 421.784 1.00 173.43 ? 38  TRP L CZ3 1 
ATOM 2186 C CH2 . TRP C 2 34  ? 273.980 330.091 420.917 1.00 173.43 ? 38  TRP L CH2 1 
ATOM 2187 N N   . LEU C 2 35  ? 266.606 328.230 421.803 1.00 170.64 ? 39  LEU L N   1 
ATOM 2188 C CA  . LEU C 2 35  ? 265.337 328.294 422.508 1.00 170.64 ? 39  LEU L CA  1 
ATOM 2189 C C   . LEU C 2 35  ? 265.423 329.306 423.643 1.00 170.64 ? 39  LEU L C   1 
ATOM 2190 O O   . LEU C 2 35  ? 266.480 329.489 424.254 1.00 170.64 ? 39  LEU L O   1 
ATOM 2191 C CB  . LEU C 2 35  ? 264.949 326.922 423.071 1.00 170.64 ? 39  LEU L CB  1 
ATOM 2192 C CG  . LEU C 2 35  ? 264.257 325.892 422.171 1.00 170.64 ? 39  LEU L CG  1 
ATOM 2193 C CD1 . LEU C 2 35  ? 262.896 326.397 421.726 1.00 170.64 ? 39  LEU L CD1 1 
ATOM 2194 C CD2 . LEU C 2 35  ? 265.114 325.513 420.969 1.00 170.64 ? 39  LEU L CD2 1 
ATOM 2195 N N   . GLN C 2 36  ? 264.301 329.965 423.920 1.00 174.06 ? 40  GLN L N   1 
ATOM 2196 C CA  . GLN C 2 36  ? 264.196 330.879 425.046 1.00 174.06 ? 40  GLN L CA  1 
ATOM 2197 C C   . GLN C 2 36  ? 263.142 330.370 426.018 1.00 174.06 ? 40  GLN L C   1 
ATOM 2198 O O   . GLN C 2 36  ? 262.179 329.703 425.632 1.00 174.06 ? 40  GLN L O   1 
ATOM 2199 C CB  . GLN C 2 36  ? 263.840 332.303 424.599 1.00 174.06 ? 40  GLN L CB  1 
ATOM 2200 C CG  . GLN C 2 36  ? 262.468 332.439 423.968 1.00 174.06 ? 40  GLN L CG  1 
ATOM 2201 C CD  . GLN C 2 36  ? 262.189 333.850 423.493 1.00 174.06 ? 40  GLN L CD  1 
ATOM 2202 O OE1 . GLN C 2 36  ? 263.006 334.752 423.679 1.00 174.06 ? 40  GLN L OE1 1 
ATOM 2203 N NE2 . GLN C 2 36  ? 261.029 334.051 422.880 1.00 174.06 ? 40  GLN L NE2 1 
ATOM 2204 N N   . GLN C 2 37  ? 263.332 330.701 427.292 1.00 177.64 ? 41  GLN L N   1 
ATOM 2205 C CA  . GLN C 2 37  ? 262.451 330.254 428.366 1.00 177.64 ? 41  GLN L CA  1 
ATOM 2206 C C   . GLN C 2 37  ? 261.614 331.435 428.832 1.00 177.64 ? 41  GLN L C   1 
ATOM 2207 O O   . GLN C 2 37  ? 262.162 332.456 429.259 1.00 177.64 ? 41  GLN L O   1 
ATOM 2208 C CB  . GLN C 2 37  ? 263.255 329.677 429.531 1.00 177.64 ? 41  GLN L CB  1 
ATOM 2209 C CG  . GLN C 2 37  ? 262.411 329.117 430.666 1.00 177.64 ? 41  GLN L CG  1 
ATOM 2210 C CD  . GLN C 2 37  ? 261.624 327.891 430.262 1.00 177.64 ? 41  GLN L CD  1 
ATOM 2211 O OE1 . GLN C 2 37  ? 262.132 327.021 429.557 1.00 177.64 ? 41  GLN L OE1 1 
ATOM 2212 N NE2 . GLN C 2 37  ? 260.373 327.815 430.703 1.00 177.64 ? 41  GLN L NE2 1 
ATOM 2213 N N   . LYS C 2 38  ? 260.299 331.306 428.743 1.00 180.07 ? 42  LYS L N   1 
ATOM 2214 C CA  . LYS C 2 38  ? 259.424 332.261 429.408 1.00 180.07 ? 42  LYS L CA  1 
ATOM 2215 C C   . LYS C 2 38  ? 259.490 332.026 430.912 1.00 180.07 ? 42  LYS L C   1 
ATOM 2216 O O   . LYS C 2 38  ? 259.651 330.879 431.346 1.00 180.07 ? 42  LYS L O   1 
ATOM 2217 C CB  . LYS C 2 38  ? 257.986 332.133 428.908 1.00 180.07 ? 42  LYS L CB  1 
ATOM 2218 C CG  . LYS C 2 38  ? 257.816 332.279 427.401 1.00 180.07 ? 42  LYS L CG  1 
ATOM 2219 C CD  . LYS C 2 38  ? 258.742 333.337 426.821 1.00 180.07 ? 42  LYS L CD  1 
ATOM 2220 C CE  . LYS C 2 38  ? 258.537 333.485 425.323 1.00 180.07 ? 42  LYS L CE  1 
ATOM 2221 N NZ  . LYS C 2 38  ? 257.092 333.478 424.963 1.00 180.07 ? 42  LYS L NZ  1 
ATOM 2222 N N   . PRO C 2 39  ? 259.392 333.072 431.735 1.00 183.38 ? 43  PRO L N   1 
ATOM 2223 C CA  . PRO C 2 39  ? 259.489 332.865 433.189 1.00 183.38 ? 43  PRO L CA  1 
ATOM 2224 C C   . PRO C 2 39  ? 258.438 331.918 433.739 1.00 183.38 ? 43  PRO L C   1 
ATOM 2225 O O   . PRO C 2 39  ? 258.733 331.151 434.664 1.00 183.38 ? 43  PRO L O   1 
ATOM 2226 C CB  . PRO C 2 39  ? 259.324 334.283 433.757 1.00 183.38 ? 43  PRO L CB  1 
ATOM 2227 C CG  . PRO C 2 39  ? 259.680 335.194 432.626 1.00 183.38 ? 43  PRO L CG  1 
ATOM 2228 C CD  . PRO C 2 39  ? 259.226 334.492 431.386 1.00 183.38 ? 43  PRO L CD  1 
ATOM 2229 N N   . ASP C 2 40  ? 257.221 331.937 433.189 1.00 185.12 ? 44  ASP L N   1 
ATOM 2230 C CA  . ASP C 2 40  ? 256.136 331.097 433.683 1.00 185.12 ? 44  ASP L CA  1 
ATOM 2231 C C   . ASP C 2 40  ? 255.369 330.421 432.551 1.00 185.12 ? 44  ASP L C   1 
ATOM 2232 O O   . ASP C 2 40  ? 254.201 330.063 432.732 1.00 185.12 ? 44  ASP L O   1 
ATOM 2233 C CB  . ASP C 2 40  ? 255.175 331.915 434.550 1.00 185.12 ? 44  ASP L CB  1 
ATOM 2234 C CG  . ASP C 2 40  ? 255.804 332.364 435.856 1.00 185.12 ? 44  ASP L CG  1 
ATOM 2235 O OD1 . ASP C 2 40  ? 256.629 331.609 436.412 1.00 185.12 ? 44  ASP L OD1 1 
ATOM 2236 O OD2 . ASP C 2 40  ? 255.474 333.474 436.324 1.00 185.12 ? 44  ASP L OD2 1 
ATOM 2237 N N   . GLY C 2 41  ? 255.993 330.236 431.392 1.00 182.39 ? 45  GLY L N   1 
ATOM 2238 C CA  . GLY C 2 41  ? 255.292 329.655 430.265 1.00 182.39 ? 45  GLY L CA  1 
ATOM 2239 C C   . GLY C 2 41  ? 256.097 328.645 429.474 1.00 182.39 ? 45  GLY L C   1 
ATOM 2240 O O   . GLY C 2 41  ? 257.114 328.133 429.951 1.00 182.39 ? 45  GLY L O   1 
ATOM 2241 N N   . THR C 2 42  ? 255.645 328.356 428.257 1.00 180.62 ? 46  THR L N   1 
ATOM 2242 C CA  . THR C 2 42  ? 256.311 327.400 427.384 1.00 180.62 ? 46  THR L CA  1 
ATOM 2243 C C   . THR C 2 42  ? 257.513 328.070 426.721 1.00 180.62 ? 46  THR L C   1 
ATOM 2244 O O   . THR C 2 42  ? 257.952 329.152 427.120 1.00 180.62 ? 46  THR L O   1 
ATOM 2245 C CB  . THR C 2 42  ? 255.328 326.845 426.357 1.00 180.62 ? 46  THR L CB  1 
ATOM 2246 O OG1 . THR C 2 42  ? 254.739 327.927 425.624 1.00 180.62 ? 46  THR L OG1 1 
ATOM 2247 C CG2 . THR C 2 42  ? 254.232 326.044 427.046 1.00 180.62 ? 46  THR L CG2 1 
ATOM 2248 N N   . ILE C 2 43  ? 258.071 327.426 425.697 1.00 171.32 ? 47  ILE L N   1 
ATOM 2249 C CA  . ILE C 2 43  ? 259.257 327.925 425.019 1.00 171.32 ? 47  ILE L CA  1 
ATOM 2250 C C   . ILE C 2 43  ? 258.977 328.046 423.527 1.00 171.32 ? 47  ILE L C   1 
ATOM 2251 O O   . ILE C 2 43  ? 258.083 327.395 422.980 1.00 171.32 ? 47  ILE L O   1 
ATOM 2252 C CB  . ILE C 2 43  ? 260.485 327.028 425.267 1.00 171.32 ? 47  ILE L CB  1 
ATOM 2253 C CG1 . ILE C 2 43  ? 260.246 325.624 424.715 1.00 171.32 ? 47  ILE L CG1 1 
ATOM 2254 C CG2 . ILE C 2 43  ? 260.798 326.963 426.745 1.00 171.32 ? 47  ILE L CG2 1 
ATOM 2255 C CD1 . ILE C 2 43  ? 261.486 324.764 424.716 1.00 171.32 ? 47  ILE L CD1 1 
ATOM 2256 N N   . LYS C 2 44  ? 259.760 328.901 422.873 1.00 168.63 ? 48  LYS L N   1 
ATOM 2257 C CA  . LYS C 2 44  ? 259.601 329.173 421.452 1.00 168.63 ? 48  LYS L CA  1 
ATOM 2258 C C   . LYS C 2 44  ? 260.978 329.295 420.816 1.00 168.63 ? 48  LYS L C   1 
ATOM 2259 O O   . LYS C 2 44  ? 261.878 329.920 421.384 1.00 168.63 ? 48  LYS L O   1 
ATOM 2260 C CB  . LYS C 2 44  ? 258.767 330.444 421.234 1.00 168.63 ? 48  LYS L CB  1 
ATOM 2261 C CG  . LYS C 2 44  ? 258.265 330.645 419.816 1.00 168.63 ? 48  LYS L CG  1 
ATOM 2262 C CD  . LYS C 2 44  ? 258.369 332.105 419.403 1.00 168.63 ? 48  LYS L CD  1 
ATOM 2263 C CE  . LYS C 2 44  ? 259.805 332.540 419.204 1.00 168.63 ? 48  LYS L CE  1 
ATOM 2264 N NZ  . LYS C 2 44  ? 259.901 333.986 418.865 1.00 168.63 ? 48  LYS L NZ  1 
ATOM 2265 N N   . ARG C 2 45  ? 261.135 328.688 419.644 1.00 162.35 ? 49  ARG L N   1 
ATOM 2266 C CA  . ARG C 2 45  ? 262.426 328.622 418.976 1.00 162.35 ? 49  ARG L CA  1 
ATOM 2267 C C   . ARG C 2 45  ? 262.763 329.944 418.298 1.00 162.35 ? 49  ARG L C   1 
ATOM 2268 O O   . ARG C 2 45  ? 261.888 330.687 417.848 1.00 162.35 ? 49  ARG L O   1 
ATOM 2269 C CB  . ARG C 2 45  ? 262.436 327.480 417.962 1.00 162.35 ? 49  ARG L CB  1 
ATOM 2270 C CG  . ARG C 2 45  ? 261.177 327.393 417.121 1.00 162.35 ? 49  ARG L CG  1 
ATOM 2271 C CD  . ARG C 2 45  ? 261.401 326.578 415.861 1.00 162.35 ? 49  ARG L CD  1 
ATOM 2272 N NE  . ARG C 2 45  ? 261.628 327.387 414.673 1.00 162.35 ? 49  ARG L NE  1 
ATOM 2273 C CZ  . ARG C 2 45  ? 261.833 326.883 413.464 1.00 162.35 ? 49  ARG L CZ  1 
ATOM 2274 N NH1 . ARG C 2 45  ? 261.894 325.577 413.262 1.00 162.35 ? 49  ARG L NH1 1 
ATOM 2275 N NH2 . ARG C 2 45  ? 261.971 327.708 412.432 1.00 162.35 ? 49  ARG L NH2 1 
ATOM 2276 N N   . LEU C 2 46  ? 264.064 330.222 418.209 1.00 170.06 ? 50  LEU L N   1 
ATOM 2277 C CA  . LEU C 2 46  ? 264.556 331.500 417.713 1.00 170.06 ? 50  LEU L CA  1 
ATOM 2278 C C   . LEU C 2 46  ? 265.133 331.391 416.307 1.00 170.06 ? 50  LEU L C   1 
ATOM 2279 O O   . LEU C 2 46  ? 264.693 332.109 415.405 1.00 170.06 ? 50  LEU L O   1 
ATOM 2280 C CB  . LEU C 2 46  ? 265.606 332.074 418.676 1.00 170.06 ? 50  LEU L CB  1 
ATOM 2281 C CG  . LEU C 2 46  ? 265.129 332.862 419.900 1.00 170.06 ? 50  LEU L CG  1 
ATOM 2282 C CD1 . LEU C 2 46  ? 264.398 334.126 419.471 1.00 170.06 ? 50  LEU L CD1 1 
ATOM 2283 C CD2 . LEU C 2 46  ? 264.264 332.022 420.827 1.00 170.06 ? 50  LEU L CD2 1 
ATOM 2284 N N   . ILE C 2 47  ? 266.118 330.522 416.091 1.00 168.03 ? 51  ILE L N   1 
ATOM 2285 C CA  . ILE C 2 47  ? 266.688 330.305 414.766 1.00 168.03 ? 51  ILE L CA  1 
ATOM 2286 C C   . ILE C 2 47  ? 266.742 328.805 414.515 1.00 168.03 ? 51  ILE L C   1 
ATOM 2287 O O   . ILE C 2 47  ? 267.394 328.070 415.267 1.00 168.03 ? 51  ILE L O   1 
ATOM 2288 C CB  . ILE C 2 47  ? 268.089 330.924 414.603 1.00 168.03 ? 51  ILE L CB  1 
ATOM 2289 C CG1 . ILE C 2 47  ? 268.123 332.401 415.009 1.00 168.03 ? 51  ILE L CG1 1 
ATOM 2290 C CG2 . ILE C 2 47  ? 268.539 330.811 413.167 1.00 168.03 ? 51  ILE L CG2 1 
ATOM 2291 C CD1 . ILE C 2 47  ? 268.322 332.655 416.489 1.00 168.03 ? 51  ILE L CD1 1 
ATOM 2292 N N   . TYR C 2 48  ? 266.063 328.352 413.459 1.00 167.68 ? 52  TYR L N   1 
ATOM 2293 C CA  . TYR C 2 48  ? 266.075 326.933 413.119 1.00 167.68 ? 52  TYR L CA  1 
ATOM 2294 C C   . TYR C 2 48  ? 267.418 326.515 412.534 1.00 167.68 ? 52  TYR L C   1 
ATOM 2295 O O   . TYR C 2 48  ? 267.977 325.478 412.911 1.00 167.68 ? 52  TYR L O   1 
ATOM 2296 C CB  . TYR C 2 48  ? 264.926 326.618 412.159 1.00 167.68 ? 52  TYR L CB  1 
ATOM 2297 C CG  . TYR C 2 48  ? 265.001 327.310 410.814 1.00 167.68 ? 52  TYR L CG  1 
ATOM 2298 C CD1 . TYR C 2 48  ? 264.426 328.560 410.627 1.00 167.68 ? 52  TYR L CD1 1 
ATOM 2299 C CD2 . TYR C 2 48  ? 265.602 326.696 409.723 1.00 167.68 ? 52  TYR L CD2 1 
ATOM 2300 C CE1 . TYR C 2 48  ? 264.478 329.195 409.404 1.00 167.68 ? 52  TYR L CE1 1 
ATOM 2301 C CE2 . TYR C 2 48  ? 265.658 327.324 408.494 1.00 167.68 ? 52  TYR L CE2 1 
ATOM 2302 C CZ  . TYR C 2 48  ? 265.093 328.572 408.341 1.00 167.68 ? 52  TYR L CZ  1 
ATOM 2303 O OH  . TYR C 2 48  ? 265.143 329.202 407.120 1.00 167.68 ? 52  TYR L OH  1 
ATOM 2304 N N   . ALA C 2 49  ? 267.950 327.306 411.616 1.00 172.78 ? 53  ALA L N   1 
ATOM 2305 C CA  . ALA C 2 49  ? 269.257 327.056 411.031 1.00 172.78 ? 53  ALA L CA  1 
ATOM 2306 C C   . ALA C 2 49  ? 270.306 327.797 411.860 1.00 172.78 ? 53  ALA L C   1 
ATOM 2307 O O   . ALA C 2 49  ? 270.050 328.175 413.006 1.00 172.78 ? 53  ALA L O   1 
ATOM 2308 C CB  . ALA C 2 49  ? 269.256 327.452 409.555 1.00 172.78 ? 53  ALA L CB  1 
ATOM 2309 N N   . THR C 2 50  ? 271.515 327.958 411.323 1.00 172.96 ? 54  THR L N   1 
ATOM 2310 C CA  . THR C 2 50  ? 272.547 328.683 412.053 1.00 172.96 ? 54  THR L CA  1 
ATOM 2311 C C   . THR C 2 50  ? 272.148 330.137 412.287 1.00 172.96 ? 54  THR L C   1 
ATOM 2312 O O   . THR C 2 50  ? 272.174 330.623 413.423 1.00 172.96 ? 54  THR L O   1 
ATOM 2313 C CB  . THR C 2 50  ? 273.873 328.604 411.299 1.00 172.96 ? 54  THR L CB  1 
ATOM 2314 O OG1 . THR C 2 50  ? 273.833 329.483 410.168 1.00 172.96 ? 54  THR L OG1 1 
ATOM 2315 C CG2 . THR C 2 50  ? 274.126 327.183 410.821 1.00 172.96 ? 54  THR L CG2 1 
ATOM 2316 N N   . SER C 2 51  ? 271.773 330.856 411.219 1.00 171.97 ? 55  SER L N   1 
ATOM 2317 C CA  . SER C 2 51  ? 271.522 332.286 411.367 1.00 171.97 ? 55  SER L CA  1 
ATOM 2318 C C   . SER C 2 51  ? 270.370 332.816 410.512 1.00 171.97 ? 55  SER L C   1 
ATOM 2319 O O   . SER C 2 51  ? 270.390 333.995 410.141 1.00 171.97 ? 55  SER L O   1 
ATOM 2320 C CB  . SER C 2 51  ? 272.789 333.085 411.043 1.00 171.97 ? 55  SER L CB  1 
ATOM 2321 O OG  . SER C 2 51  ? 273.078 333.046 409.657 1.00 171.97 ? 55  SER L OG  1 
ATOM 2322 N N   . ASN C 2 52  ? 269.370 331.998 410.180 1.00 169.04 ? 56  ASN L N   1 
ATOM 2323 C CA  . ASN C 2 52  ? 268.299 332.485 409.314 1.00 169.04 ? 56  ASN L CA  1 
ATOM 2324 C C   . ASN C 2 52  ? 267.138 333.135 410.060 1.00 169.04 ? 56  ASN L C   1 
ATOM 2325 O O   . ASN C 2 52  ? 266.235 333.661 409.401 1.00 169.04 ? 56  ASN L O   1 
ATOM 2326 C CB  . ASN C 2 52  ? 267.780 331.359 408.417 1.00 169.04 ? 56  ASN L CB  1 
ATOM 2327 C CG  . ASN C 2 52  ? 268.835 330.853 407.453 1.00 169.04 ? 56  ASN L CG  1 
ATOM 2328 O OD1 . ASN C 2 52  ? 269.273 329.710 407.531 1.00 169.04 ? 56  ASN L OD1 1 
ATOM 2329 N ND2 . ASN C 2 52  ? 269.247 331.713 406.530 1.00 169.04 ? 56  ASN L ND2 1 
ATOM 2330 N N   . LEU C 2 53  ? 267.136 333.124 411.395 1.00 173.63 ? 57  LEU L N   1 
ATOM 2331 C CA  . LEU C 2 53  ? 266.246 333.967 412.199 1.00 173.63 ? 57  LEU L CA  1 
ATOM 2332 C C   . LEU C 2 53  ? 264.773 333.683 411.875 1.00 173.63 ? 57  LEU L C   1 
ATOM 2333 O O   . LEU C 2 53  ? 264.120 334.396 411.112 1.00 173.63 ? 57  LEU L O   1 
ATOM 2334 C CB  . LEU C 2 53  ? 266.595 335.454 412.021 1.00 173.63 ? 57  LEU L CB  1 
ATOM 2335 C CG  . LEU C 2 53  ? 265.926 336.525 412.904 1.00 173.63 ? 57  LEU L CG  1 
ATOM 2336 C CD1 . LEU C 2 53  ? 266.849 337.724 413.019 1.00 173.63 ? 57  LEU L CD1 1 
ATOM 2337 C CD2 . LEU C 2 53  ? 264.557 336.995 412.433 1.00 173.63 ? 57  LEU L CD2 1 
ATOM 2338 N N   . ASP C 2 54  ? 264.306 332.542 412.385 1.00 170.09 ? 58  ASP L N   1 
ATOM 2339 C CA  . ASP C 2 54  ? 262.884 332.211 412.337 1.00 170.09 ? 58  ASP L CA  1 
ATOM 2340 C C   . ASP C 2 54  ? 262.023 333.420 412.682 1.00 170.09 ? 58  ASP L C   1 
ATOM 2341 O O   . ASP C 2 54  ? 262.378 334.233 413.538 1.00 170.09 ? 58  ASP L O   1 
ATOM 2342 C CB  . ASP C 2 54  ? 262.568 331.074 413.313 1.00 170.09 ? 58  ASP L CB  1 
ATOM 2343 C CG  . ASP C 2 54  ? 261.150 330.549 413.163 1.00 170.09 ? 58  ASP L CG  1 
ATOM 2344 O OD1 . ASP C 2 54  ? 260.389 331.078 412.324 1.00 170.09 ? 58  ASP L OD1 1 
ATOM 2345 O OD2 . ASP C 2 54  ? 260.786 329.614 413.904 1.00 170.09 ? 58  ASP L OD2 1 
ATOM 2346 N N   . SER C 2 55  ? 260.877 333.516 412.011 1.00 170.83 ? 59  SER L N   1 
ATOM 2347 C CA  . SER C 2 55  ? 259.977 334.646 412.175 1.00 170.83 ? 59  SER L CA  1 
ATOM 2348 C C   . SER C 2 55  ? 259.376 334.663 413.580 1.00 170.83 ? 59  SER L C   1 
ATOM 2349 O O   . SER C 2 55  ? 259.579 333.755 414.391 1.00 170.83 ? 59  SER L O   1 
ATOM 2350 C CB  . SER C 2 55  ? 258.865 334.599 411.128 1.00 170.83 ? 59  SER L CB  1 
ATOM 2351 O OG  . SER C 2 55  ? 257.846 333.691 411.509 1.00 170.83 ? 59  SER L OG  1 
ATOM 2352 N N   . GLY C 2 56  ? 258.616 335.718 413.859 1.00 171.38 ? 60  GLY L N   1 
ATOM 2353 C CA  . GLY C 2 56  ? 258.030 335.904 415.169 1.00 171.38 ? 60  GLY L CA  1 
ATOM 2354 C C   . GLY C 2 56  ? 258.933 336.552 416.191 1.00 171.38 ? 60  GLY L C   1 
ATOM 2355 O O   . GLY C 2 56  ? 258.580 336.581 417.375 1.00 171.38 ? 60  GLY L O   1 
ATOM 2356 N N   . VAL C 2 57  ? 260.085 337.071 415.778 1.00 178.60 ? 61  VAL L N   1 
ATOM 2357 C CA  . VAL C 2 57  ? 261.021 337.716 416.696 1.00 178.60 ? 61  VAL L CA  1 
ATOM 2358 C C   . VAL C 2 57  ? 261.497 339.012 416.048 1.00 178.60 ? 61  VAL L C   1 
ATOM 2359 O O   . VAL C 2 57  ? 261.601 339.081 414.815 1.00 178.60 ? 61  VAL L O   1 
ATOM 2360 C CB  . VAL C 2 57  ? 262.191 336.776 417.038 1.00 178.60 ? 61  VAL L CB  1 
ATOM 2361 C CG1 . VAL C 2 57  ? 263.030 336.482 415.803 1.00 178.60 ? 61  VAL L CG1 1 
ATOM 2362 C CG2 . VAL C 2 57  ? 263.051 337.337 418.158 1.00 178.60 ? 61  VAL L CG2 1 
ATOM 2363 N N   . PRO C 2 58  ? 261.762 340.067 416.819 1.00 183.62 ? 62  PRO L N   1 
ATOM 2364 C CA  . PRO C 2 58  ? 262.334 341.283 416.228 1.00 183.62 ? 62  PRO L CA  1 
ATOM 2365 C C   . PRO C 2 58  ? 263.697 341.020 415.603 1.00 183.62 ? 62  PRO L C   1 
ATOM 2366 O O   . PRO C 2 58  ? 264.462 340.171 416.065 1.00 183.62 ? 62  PRO L O   1 
ATOM 2367 C CB  . PRO C 2 58  ? 262.434 342.247 417.418 1.00 183.62 ? 62  PRO L CB  1 
ATOM 2368 C CG  . PRO C 2 58  ? 262.237 341.393 418.645 1.00 183.62 ? 62  PRO L CG  1 
ATOM 2369 C CD  . PRO C 2 58  ? 261.334 340.293 418.208 1.00 183.62 ? 62  PRO L CD  1 
ATOM 2370 N N   . LYS C 2 59  ? 263.998 341.771 414.542 1.00 183.95 ? 63  LYS L N   1 
ATOM 2371 C CA  . LYS C 2 59  ? 265.233 341.599 413.778 1.00 183.95 ? 63  LYS L CA  1 
ATOM 2372 C C   . LYS C 2 59  ? 266.429 342.138 414.566 1.00 183.95 ? 63  LYS L C   1 
ATOM 2373 O O   . LYS C 2 59  ? 267.053 343.138 414.215 1.00 183.95 ? 63  LYS L O   1 
ATOM 2374 C CB  . LYS C 2 59  ? 265.111 342.292 412.427 1.00 183.95 ? 63  LYS L CB  1 
ATOM 2375 C CG  . LYS C 2 59  ? 264.039 341.722 411.517 1.00 183.95 ? 63  LYS L CG  1 
ATOM 2376 C CD  . LYS C 2 59  ? 264.326 340.275 411.175 1.00 183.95 ? 63  LYS L CD  1 
ATOM 2377 C CE  . LYS C 2 59  ? 265.634 340.138 410.416 1.00 183.95 ? 63  LYS L CE  1 
ATOM 2378 N NZ  . LYS C 2 59  ? 265.491 340.558 408.996 1.00 183.95 ? 63  LYS L NZ  1 
ATOM 2379 N N   . ARG C 2 60  ? 266.740 341.447 415.663 1.00 186.41 ? 64  ARG L N   1 
ATOM 2380 C CA  . ARG C 2 60  ? 267.765 341.901 416.591 1.00 186.41 ? 64  ARG L CA  1 
ATOM 2381 C C   . ARG C 2 60  ? 268.671 340.796 417.115 1.00 186.41 ? 64  ARG L C   1 
ATOM 2382 O O   . ARG C 2 60  ? 269.477 341.061 418.013 1.00 186.41 ? 64  ARG L O   1 
ATOM 2383 C CB  . ARG C 2 60  ? 267.116 342.622 417.782 1.00 186.41 ? 64  ARG L CB  1 
ATOM 2384 C CG  . ARG C 2 60  ? 266.224 343.796 417.396 1.00 186.41 ? 64  ARG L CG  1 
ATOM 2385 C CD  . ARG C 2 60  ? 265.248 344.188 418.504 1.00 186.41 ? 64  ARG L CD  1 
ATOM 2386 N NE  . ARG C 2 60  ? 265.732 343.942 419.860 1.00 186.41 ? 64  ARG L NE  1 
ATOM 2387 C CZ  . ARG C 2 60  ? 266.811 344.489 420.405 1.00 186.41 ? 64  ARG L CZ  1 
ATOM 2388 N NH1 . ARG C 2 60  ? 267.553 345.367 419.749 1.00 186.41 ? 64  ARG L NH1 1 
ATOM 2389 N NH2 . ARG C 2 60  ? 267.150 344.149 421.644 1.00 186.41 ? 64  ARG L NH2 1 
ATOM 2390 N N   . PHE C 2 61  ? 268.570 339.577 416.593 1.00 179.97 ? 65  PHE L N   1 
ATOM 2391 C CA  . PHE C 2 61  ? 269.371 338.457 417.062 1.00 179.97 ? 65  PHE L CA  1 
ATOM 2392 C C   . PHE C 2 61  ? 269.995 337.738 415.876 1.00 179.97 ? 65  PHE L C   1 
ATOM 2393 O O   . PHE C 2 61  ? 269.463 337.780 414.763 1.00 179.97 ? 65  PHE L O   1 
ATOM 2394 C CB  . PHE C 2 61  ? 268.528 337.482 417.885 1.00 179.97 ? 65  PHE L CB  1 
ATOM 2395 C CG  . PHE C 2 61  ? 267.788 338.132 419.017 1.00 179.97 ? 65  PHE L CG  1 
ATOM 2396 C CD1 . PHE C 2 61  ? 268.471 338.834 419.996 1.00 179.97 ? 65  PHE L CD1 1 
ATOM 2397 C CD2 . PHE C 2 61  ? 266.410 338.046 419.102 1.00 179.97 ? 65  PHE L CD2 1 
ATOM 2398 C CE1 . PHE C 2 61  ? 267.793 339.437 421.036 1.00 179.97 ? 65  PHE L CE1 1 
ATOM 2399 C CE2 . PHE C 2 61  ? 265.725 338.646 420.141 1.00 179.97 ? 65  PHE L CE2 1 
ATOM 2400 C CZ  . PHE C 2 61  ? 266.418 339.342 421.110 1.00 179.97 ? 65  PHE L CZ  1 
ATOM 2401 N N   . SER C 2 62  ? 271.132 337.086 416.114 1.00 179.06 ? 66  SER L N   1 
ATOM 2402 C CA  . SER C 2 62  ? 271.829 336.370 415.055 1.00 179.06 ? 66  SER L CA  1 
ATOM 2403 C C   . SER C 2 62  ? 272.665 335.255 415.661 1.00 179.06 ? 66  SER L C   1 
ATOM 2404 O O   . SER C 2 62  ? 273.454 335.496 416.580 1.00 179.06 ? 66  SER L O   1 
ATOM 2405 C CB  . SER C 2 62  ? 272.719 337.316 414.242 1.00 179.06 ? 66  SER L CB  1 
ATOM 2406 O OG  . SER C 2 62  ? 273.799 337.797 415.022 1.00 179.06 ? 66  SER L OG  1 
ATOM 2407 N N   . GLY C 2 63  ? 272.492 334.043 415.141 1.00 176.34 ? 67  GLY L N   1 
ATOM 2408 C CA  . GLY C 2 63  ? 273.304 332.919 415.562 1.00 176.34 ? 67  GLY L CA  1 
ATOM 2409 C C   . GLY C 2 63  ? 274.586 332.827 414.762 1.00 176.34 ? 67  GLY L C   1 
ATOM 2410 O O   . GLY C 2 63  ? 274.586 332.332 413.631 1.00 176.34 ? 67  GLY L O   1 
ATOM 2411 N N   . SER C 2 64  ? 275.685 333.301 415.341 1.00 179.39 ? 68  SER L N   1 
ATOM 2412 C CA  . SER C 2 64  ? 276.945 333.371 414.618 1.00 179.39 ? 68  SER L CA  1 
ATOM 2413 C C   . SER C 2 64  ? 277.480 331.977 414.312 1.00 179.39 ? 68  SER L C   1 
ATOM 2414 O O   . SER C 2 64  ? 277.326 331.037 415.096 1.00 179.39 ? 68  SER L O   1 
ATOM 2415 C CB  . SER C 2 64  ? 277.979 334.155 415.423 1.00 179.39 ? 68  SER L CB  1 
ATOM 2416 O OG  . SER C 2 64  ? 278.405 333.413 416.552 1.00 179.39 ? 68  SER L OG  1 
ATOM 2417 N N   . ARG C 2 65  ? 278.121 331.855 413.153 1.00 181.66 ? 69  ARG L N   1 
ATOM 2418 C CA  . ARG C 2 65  ? 278.734 330.611 412.710 1.00 181.66 ? 69  ARG L CA  1 
ATOM 2419 C C   . ARG C 2 65  ? 280.244 330.783 412.686 1.00 181.66 ? 69  ARG L C   1 
ATOM 2420 O O   . ARG C 2 65  ? 280.754 331.752 412.113 1.00 181.66 ? 69  ARG L O   1 
ATOM 2421 C CB  . ARG C 2 65  ? 278.222 330.208 411.324 1.00 181.66 ? 69  ARG L CB  1 
ATOM 2422 C CG  . ARG C 2 65  ? 278.347 328.724 411.021 1.00 181.66 ? 69  ARG L CG  1 
ATOM 2423 C CD  . ARG C 2 65  ? 279.532 328.442 410.113 1.00 181.66 ? 69  ARG L CD  1 
ATOM 2424 N NE  . ARG C 2 65  ? 279.654 327.023 409.802 1.00 181.66 ? 69  ARG L NE  1 
ATOM 2425 C CZ  . ARG C 2 65  ? 280.384 326.165 410.500 1.00 181.66 ? 69  ARG L CZ  1 
ATOM 2426 N NH1 . ARG C 2 65  ? 281.083 326.550 411.555 1.00 181.66 ? 69  ARG L NH1 1 
ATOM 2427 N NH2 . ARG C 2 65  ? 280.414 324.888 410.130 1.00 181.66 ? 69  ARG L NH2 1 
ATOM 2428 N N   . SER C 2 66  ? 280.954 329.847 413.309 1.00 184.12 ? 70  SER L N   1 
ATOM 2429 C CA  . SER C 2 66  ? 282.408 329.898 413.365 1.00 184.12 ? 70  SER L CA  1 
ATOM 2430 C C   . SER C 2 66  ? 282.932 328.487 413.588 1.00 184.12 ? 70  SER L C   1 
ATOM 2431 O O   . SER C 2 66  ? 282.175 327.564 413.900 1.00 184.12 ? 70  SER L O   1 
ATOM 2432 C CB  . SER C 2 66  ? 282.894 330.854 414.458 1.00 184.12 ? 70  SER L CB  1 
ATOM 2433 O OG  . SER C 2 66  ? 282.639 332.202 414.104 1.00 184.12 ? 70  SER L OG  1 
ATOM 2434 N N   . GLY C 2 67  ? 284.242 328.332 413.414 1.00 186.93 ? 71  GLY L N   1 
ATOM 2435 C CA  . GLY C 2 67  ? 284.879 327.032 413.489 1.00 186.93 ? 71  GLY L CA  1 
ATOM 2436 C C   . GLY C 2 67  ? 284.693 326.308 414.806 1.00 186.93 ? 71  GLY L C   1 
ATOM 2437 O O   . GLY C 2 67  ? 285.243 326.715 415.834 1.00 186.93 ? 71  GLY L O   1 
ATOM 2438 N N   . SER C 2 68  ? 283.903 325.232 414.778 1.00 189.57 ? 72  SER L N   1 
ATOM 2439 C CA  . SER C 2 68  ? 283.694 324.348 415.928 1.00 189.57 ? 72  SER L CA  1 
ATOM 2440 C C   . SER C 2 68  ? 283.123 325.090 417.134 1.00 189.57 ? 72  SER L C   1 
ATOM 2441 O O   . SER C 2 68  ? 283.217 324.612 418.267 1.00 189.57 ? 72  SER L O   1 
ATOM 2442 C CB  . SER C 2 68  ? 284.988 323.625 416.315 1.00 189.57 ? 72  SER L CB  1 
ATOM 2443 O OG  . SER C 2 68  ? 285.888 324.501 416.970 1.00 189.57 ? 72  SER L OG  1 
ATOM 2444 N N   . ASP C 2 69  ? 282.518 326.253 416.906 1.00 188.79 ? 73  ASP L N   1 
ATOM 2445 C CA  . ASP C 2 69  ? 281.896 327.015 417.987 1.00 188.79 ? 73  ASP L CA  1 
ATOM 2446 C C   . ASP C 2 69  ? 280.875 327.985 417.415 1.00 188.79 ? 73  ASP L C   1 
ATOM 2447 O O   . ASP C 2 69  ? 281.117 328.609 416.377 1.00 188.79 ? 73  ASP L O   1 
ATOM 2448 C CB  . ASP C 2 69  ? 282.957 327.731 418.846 1.00 188.79 ? 73  ASP L CB  1 
ATOM 2449 C CG  . ASP C 2 69  ? 283.779 328.756 418.073 1.00 188.79 ? 73  ASP L CG  1 
ATOM 2450 O OD1 . ASP C 2 69  ? 283.595 328.917 416.852 1.00 188.79 ? 73  ASP L OD1 1 
ATOM 2451 O OD2 . ASP C 2 69  ? 284.633 329.410 418.706 1.00 188.79 ? 73  ASP L OD2 1 
ATOM 2452 N N   . TYR C 2 70  ? 279.722 328.083 418.071 1.00 183.50 ? 74  TYR L N   1 
ATOM 2453 C CA  . TYR C 2 70  ? 278.615 328.911 417.622 1.00 183.50 ? 74  TYR L CA  1 
ATOM 2454 C C   . TYR C 2 70  ? 278.164 329.818 418.758 1.00 183.50 ? 74  TYR L C   1 
ATOM 2455 O O   . TYR C 2 70  ? 278.286 329.470 419.936 1.00 183.50 ? 74  TYR L O   1 
ATOM 2456 C CB  . TYR C 2 70  ? 277.441 328.050 417.143 1.00 183.50 ? 74  TYR L CB  1 
ATOM 2457 C CG  . TYR C 2 70  ? 277.780 327.135 415.990 1.00 183.50 ? 74  TYR L CG  1 
ATOM 2458 C CD1 . TYR C 2 70  ? 278.647 327.541 414.985 1.00 183.50 ? 74  TYR L CD1 1 
ATOM 2459 C CD2 . TYR C 2 70  ? 277.249 325.855 415.917 1.00 183.50 ? 74  TYR L CD2 1 
ATOM 2460 C CE1 . TYR C 2 70  ? 278.964 326.706 413.935 1.00 183.50 ? 74  TYR L CE1 1 
ATOM 2461 C CE2 . TYR C 2 70  ? 277.561 325.011 414.870 1.00 183.50 ? 74  TYR L CE2 1 
ATOM 2462 C CZ  . TYR C 2 70  ? 278.420 325.442 413.881 1.00 183.50 ? 74  TYR L CZ  1 
ATOM 2463 O OH  . TYR C 2 70  ? 278.736 324.608 412.835 1.00 183.50 ? 74  TYR L OH  1 
ATOM 2464 N N   . SER C 2 71  ? 277.640 330.987 418.397 1.00 180.25 ? 75  SER L N   1 
ATOM 2465 C CA  . SER C 2 71  ? 277.199 331.945 419.398 1.00 180.25 ? 75  SER L CA  1 
ATOM 2466 C C   . SER C 2 71  ? 275.975 332.691 418.889 1.00 180.25 ? 75  SER L C   1 
ATOM 2467 O O   . SER C 2 71  ? 275.760 332.825 417.682 1.00 180.25 ? 75  SER L O   1 
ATOM 2468 C CB  . SER C 2 71  ? 278.314 332.934 419.760 1.00 180.25 ? 75  SER L CB  1 
ATOM 2469 O OG  . SER C 2 71  ? 278.573 333.826 418.691 1.00 180.25 ? 75  SER L OG  1 
ATOM 2470 N N   . LEU C 2 72  ? 275.176 333.179 419.835 1.00 180.88 ? 76  LEU L N   1 
ATOM 2471 C CA  . LEU C 2 72  ? 273.991 333.978 419.549 1.00 180.88 ? 76  LEU L CA  1 
ATOM 2472 C C   . LEU C 2 72  ? 274.239 335.399 420.033 1.00 180.88 ? 76  LEU L C   1 
ATOM 2473 O O   . LEU C 2 72  ? 274.536 335.612 421.213 1.00 180.88 ? 76  LEU L O   1 
ATOM 2474 C CB  . LEU C 2 72  ? 272.754 333.386 420.225 1.00 180.88 ? 76  LEU L CB  1 
ATOM 2475 C CG  . LEU C 2 72  ? 271.422 334.090 419.971 1.00 180.88 ? 76  LEU L CG  1 
ATOM 2476 C CD1 . LEU C 2 72  ? 271.064 334.042 418.498 1.00 180.88 ? 76  LEU L CD1 1 
ATOM 2477 C CD2 . LEU C 2 72  ? 270.322 333.467 420.814 1.00 180.88 ? 76  LEU L CD2 1 
ATOM 2478 N N   . THR C 2 73  ? 274.102 336.363 419.130 1.00 186.49 ? 77  THR L N   1 
ATOM 2479 C CA  . THR C 2 73  ? 274.444 337.751 419.408 1.00 186.49 ? 77  THR L CA  1 
ATOM 2480 C C   . THR C 2 73  ? 273.178 338.580 419.578 1.00 186.49 ? 77  THR L C   1 
ATOM 2481 O O   . THR C 2 73  ? 272.229 338.441 418.799 1.00 186.49 ? 77  THR L O   1 
ATOM 2482 C CB  . THR C 2 73  ? 275.302 338.336 418.286 1.00 186.49 ? 77  THR L CB  1 
ATOM 2483 O OG1 . THR C 2 73  ? 274.518 338.452 417.092 1.00 186.49 ? 77  THR L OG1 1 
ATOM 2484 C CG2 . THR C 2 73  ? 276.501 337.440 418.012 1.00 186.49 ? 77  THR L CG2 1 
ATOM 2485 N N   . ILE C 2 74  ? 273.168 339.435 420.597 1.00 190.41 ? 78  ILE L N   1 
ATOM 2486 C CA  . ILE C 2 74  ? 272.086 340.385 420.823 1.00 190.41 ? 78  ILE L CA  1 
ATOM 2487 C C   . ILE C 2 74  ? 272.594 341.780 420.487 1.00 190.41 ? 78  ILE L C   1 
ATOM 2488 O O   . ILE C 2 74  ? 273.724 342.142 420.841 1.00 190.41 ? 78  ILE L O   1 
ATOM 2489 C CB  . ILE C 2 74  ? 271.564 340.310 422.269 1.00 190.41 ? 78  ILE L CB  1 
ATOM 2490 C CG1 . ILE C 2 74  ? 272.661 340.676 423.273 1.00 190.41 ? 78  ILE L CG1 1 
ATOM 2491 C CG2 . ILE C 2 74  ? 271.015 338.924 422.564 1.00 190.41 ? 78  ILE L CG2 1 
ATOM 2492 C CD1 . ILE C 2 74  ? 272.161 340.850 424.689 1.00 190.41 ? 78  ILE L CD1 1 
ATOM 2493 N N   . SER C 2 75  ? 271.775 342.553 419.775 1.00 192.87 ? 79  SER L N   1 
ATOM 2494 C CA  . SER C 2 75  ? 272.158 343.915 419.420 1.00 192.87 ? 79  SER L CA  1 
ATOM 2495 C C   . SER C 2 75  ? 272.182 344.815 420.650 1.00 192.87 ? 79  SER L C   1 
ATOM 2496 O O   . SER C 2 75  ? 273.219 345.392 420.994 1.00 192.87 ? 79  SER L O   1 
ATOM 2497 C CB  . SER C 2 75  ? 271.201 344.468 418.361 1.00 192.87 ? 79  SER L CB  1 
ATOM 2498 O OG  . SER C 2 75  ? 269.930 344.746 418.922 1.00 192.87 ? 79  SER L OG  1 
ATOM 2499 N N   . SER C 2 76  ? 271.041 344.945 421.323 1.00 192.08 ? 80  SER L N   1 
ATOM 2500 C CA  . SER C 2 76  ? 270.932 345.722 422.552 1.00 192.08 ? 80  SER L CA  1 
ATOM 2501 C C   . SER C 2 76  ? 269.754 345.185 423.346 1.00 192.08 ? 80  SER L C   1 
ATOM 2502 O O   . SER C 2 76  ? 268.642 345.104 422.820 1.00 192.08 ? 80  SER L O   1 
ATOM 2503 C CB  . SER C 2 76  ? 270.748 347.213 422.254 1.00 192.08 ? 80  SER L CB  1 
ATOM 2504 O OG  . SER C 2 76  ? 270.555 347.950 423.448 1.00 192.08 ? 80  SER L OG  1 
ATOM 2505 N N   . LEU C 2 77  ? 269.993 344.824 424.604 1.00 193.72 ? 81  LEU L N   1 
ATOM 2506 C CA  . LEU C 2 77  ? 268.948 344.217 425.417 1.00 193.72 ? 81  LEU L CA  1 
ATOM 2507 C C   . LEU C 2 77  ? 267.792 345.187 425.623 1.00 193.72 ? 81  LEU L C   1 
ATOM 2508 O O   . LEU C 2 77  ? 267.997 346.357 425.957 1.00 193.72 ? 81  LEU L O   1 
ATOM 2509 C CB  . LEU C 2 77  ? 269.511 343.780 426.767 1.00 193.72 ? 81  LEU L CB  1 
ATOM 2510 C CG  . LEU C 2 77  ? 268.510 343.069 427.681 1.00 193.72 ? 81  LEU L CG  1 
ATOM 2511 C CD1 . LEU C 2 77  ? 268.029 341.775 427.045 1.00 193.72 ? 81  LEU L CD1 1 
ATOM 2512 C CD2 . LEU C 2 77  ? 269.115 342.808 429.050 1.00 193.72 ? 81  LEU L CD2 1 
ATOM 2513 N N   . GLU C 2 78  ? 266.572 344.693 425.426 1.00 198.12 ? 82  GLU L N   1 
ATOM 2514 C CA  . GLU C 2 78  ? 265.361 345.466 425.666 1.00 198.12 ? 82  GLU L CA  1 
ATOM 2515 C C   . GLU C 2 78  ? 264.878 345.362 427.106 1.00 198.12 ? 82  GLU L C   1 
ATOM 2516 O O   . GLU C 2 78  ? 263.674 345.499 427.345 1.00 198.12 ? 82  GLU L O   1 
ATOM 2517 C CB  . GLU C 2 78  ? 264.250 345.017 424.713 1.00 198.12 ? 82  GLU L CB  1 
ATOM 2518 C CG  . GLU C 2 78  ? 264.060 343.510 424.652 1.00 198.12 ? 82  GLU L CG  1 
ATOM 2519 C CD  . GLU C 2 78  ? 263.268 343.072 423.437 1.00 198.12 ? 82  GLU L CD  1 
ATOM 2520 O OE1 . GLU C 2 78  ? 263.176 343.858 422.472 1.00 198.12 ? 82  GLU L OE1 1 
ATOM 2521 O OE2 . GLU C 2 78  ? 262.738 341.942 423.448 1.00 198.12 ? 82  GLU L OE2 1 
ATOM 2522 N N   . THR C 2 79  ? 265.785 345.065 428.040 1.00 205.69 ? 83  THR L N   1 
ATOM 2523 C CA  . THR C 2 79  ? 265.569 344.934 429.482 1.00 205.69 ? 83  THR L CA  1 
ATOM 2524 C C   . THR C 2 79  ? 264.423 343.988 429.832 1.00 205.69 ? 83  THR L C   1 
ATOM 2525 O O   . THR C 2 79  ? 263.970 343.968 430.984 1.00 205.69 ? 83  THR L O   1 
ATOM 2526 C CB  . THR C 2 79  ? 265.372 346.303 430.171 1.00 205.69 ? 83  THR L CB  1 
ATOM 2527 O OG1 . THR C 2 79  ? 265.579 346.157 431.581 1.00 205.69 ? 83  THR L OG1 1 
ATOM 2528 C CG2 . THR C 2 79  ? 263.975 346.878 429.949 1.00 205.69 ? 83  THR L CG2 1 
ATOM 2529 N N   . GLU C 2 80  ? 263.967 343.176 428.881 1.00 203.26 ? 84  GLU L N   1 
ATOM 2530 C CA  . GLU C 2 80  ? 262.905 342.207 429.106 1.00 203.26 ? 84  GLU L CA  1 
ATOM 2531 C C   . GLU C 2 80  ? 263.187 340.948 428.298 1.00 203.26 ? 84  GLU L C   1 
ATOM 2532 O O   . GLU C 2 80  ? 263.937 340.968 427.319 1.00 203.26 ? 84  GLU L O   1 
ATOM 2533 C CB  . GLU C 2 80  ? 261.525 342.770 428.723 1.00 203.26 ? 84  GLU L CB  1 
ATOM 2534 C CG  . GLU C 2 80  ? 261.099 344.011 429.495 1.00 203.26 ? 84  GLU L CG  1 
ATOM 2535 C CD  . GLU C 2 80  ? 260.863 343.728 430.965 1.00 203.26 ? 84  GLU L CD  1 
ATOM 2536 O OE1 . GLU C 2 80  ? 260.366 342.629 431.287 1.00 203.26 ? 84  GLU L OE1 1 
ATOM 2537 O OE2 . GLU C 2 80  ? 261.174 344.603 431.799 1.00 203.26 ? 84  GLU L OE2 1 
ATOM 2538 N N   . ASP C 2 81  ? 262.573 339.846 428.734 1.00 199.31 ? 85  ASP L N   1 
ATOM 2539 C CA  . ASP C 2 81  ? 262.598 338.573 428.014 1.00 199.31 ? 85  ASP L CA  1 
ATOM 2540 C C   . ASP C 2 81  ? 264.032 338.066 427.839 1.00 199.31 ? 85  ASP L C   1 
ATOM 2541 O O   . ASP C 2 81  ? 264.493 337.780 426.733 1.00 199.31 ? 85  ASP L O   1 
ATOM 2542 C CB  . ASP C 2 81  ? 261.888 338.706 426.662 1.00 199.31 ? 85  ASP L CB  1 
ATOM 2543 C CG  . ASP C 2 81  ? 260.404 338.979 426.809 1.00 199.31 ? 85  ASP L CG  1 
ATOM 2544 O OD1 . ASP C 2 81  ? 259.812 338.537 427.817 1.00 199.31 ? 85  ASP L OD1 1 
ATOM 2545 O OD2 . ASP C 2 81  ? 259.829 339.641 425.919 1.00 199.31 ? 85  ASP L OD2 1 
ATOM 2546 N N   . PHE C 2 82  ? 264.737 337.956 428.969 1.00 196.16 ? 86  PHE L N   1 
ATOM 2547 C CA  . PHE C 2 82  ? 266.149 337.596 428.931 1.00 196.16 ? 86  PHE L CA  1 
ATOM 2548 C C   . PHE C 2 82  ? 266.547 336.626 430.040 1.00 196.16 ? 86  PHE L C   1 
ATOM 2549 O O   . PHE C 2 82  ? 267.725 336.584 430.416 1.00 196.16 ? 86  PHE L O   1 
ATOM 2550 C CB  . PHE C 2 82  ? 267.024 338.857 429.013 1.00 196.16 ? 86  PHE L CB  1 
ATOM 2551 C CG  . PHE C 2 82  ? 266.969 339.554 430.349 1.00 196.16 ? 86  PHE L CG  1 
ATOM 2552 C CD1 . PHE C 2 82  ? 265.845 340.269 430.730 1.00 196.16 ? 86  PHE L CD1 1 
ATOM 2553 C CD2 . PHE C 2 82  ? 268.049 339.503 431.216 1.00 196.16 ? 86  PHE L CD2 1 
ATOM 2554 C CE1 . PHE C 2 82  ? 265.795 340.910 431.954 1.00 196.16 ? 86  PHE L CE1 1 
ATOM 2555 C CE2 . PHE C 2 82  ? 268.004 340.142 432.441 1.00 196.16 ? 86  PHE L CE2 1 
ATOM 2556 C CZ  . PHE C 2 82  ? 266.876 340.847 432.810 1.00 196.16 ? 86  PHE L CZ  1 
ATOM 2557 N N   . VAL C 2 83  ? 265.615 335.834 430.566 1.00 185.65 ? 87  VAL L N   1 
ATOM 2558 C CA  . VAL C 2 83  ? 265.915 335.035 431.751 1.00 185.65 ? 87  VAL L CA  1 
ATOM 2559 C C   . VAL C 2 83  ? 266.786 333.827 431.400 1.00 185.65 ? 87  VAL L C   1 
ATOM 2560 O O   . VAL C 2 83  ? 267.908 333.698 431.902 1.00 185.65 ? 87  VAL L O   1 
ATOM 2561 C CB  . VAL C 2 83  ? 264.614 334.654 432.494 1.00 185.65 ? 87  VAL L CB  1 
ATOM 2562 C CG1 . VAL C 2 83  ? 263.705 333.748 431.673 1.00 185.65 ? 87  VAL L CG1 1 
ATOM 2563 C CG2 . VAL C 2 83  ? 264.940 334.012 433.836 1.00 185.65 ? 87  VAL L CG2 1 
ATOM 2564 N N   . ASP C 2 84  ? 266.305 332.934 430.532 1.00 179.96 ? 88  ASP L N   1 
ATOM 2565 C CA  . ASP C 2 84  ? 267.042 331.734 430.144 1.00 179.96 ? 88  ASP L CA  1 
ATOM 2566 C C   . ASP C 2 84  ? 267.005 331.569 428.632 1.00 179.96 ? 88  ASP L C   1 
ATOM 2567 O O   . ASP C 2 84  ? 265.961 331.779 428.007 1.00 179.96 ? 88  ASP L O   1 
ATOM 2568 C CB  . ASP C 2 84  ? 266.475 330.462 430.797 1.00 179.96 ? 88  ASP L CB  1 
ATOM 2569 C CG  . ASP C 2 84  ? 266.671 330.418 432.304 1.00 179.96 ? 88  ASP L CG  1 
ATOM 2570 O OD1 . ASP C 2 84  ? 266.755 329.297 432.849 1.00 179.96 ? 88  ASP L OD1 1 
ATOM 2571 O OD2 . ASP C 2 84  ? 266.731 331.477 432.954 1.00 179.96 ? 88  ASP L OD2 1 
ATOM 2572 N N   . TYR C 2 85  ? 268.140 331.172 428.054 1.00 176.25 ? 89  TYR L N   1 
ATOM 2573 C CA  . TYR C 2 85  ? 268.246 330.830 426.642 1.00 176.25 ? 89  TYR L CA  1 
ATOM 2574 C C   . TYR C 2 85  ? 268.855 329.442 426.503 1.00 176.25 ? 89  TYR L C   1 
ATOM 2575 O O   . TYR C 2 85  ? 269.735 329.063 427.282 1.00 176.25 ? 89  TYR L O   1 
ATOM 2576 C CB  . TYR C 2 85  ? 269.101 331.846 425.869 1.00 176.25 ? 89  TYR L CB  1 
ATOM 2577 C CG  . TYR C 2 85  ? 268.345 333.052 425.354 1.00 176.25 ? 89  TYR L CG  1 
ATOM 2578 C CD1 . TYR C 2 85  ? 268.608 333.570 424.094 1.00 176.25 ? 89  TYR L CD1 1 
ATOM 2579 C CD2 . TYR C 2 85  ? 267.382 333.682 426.131 1.00 176.25 ? 89  TYR L CD2 1 
ATOM 2580 C CE1 . TYR C 2 85  ? 267.925 334.672 423.617 1.00 176.25 ? 89  TYR L CE1 1 
ATOM 2581 C CE2 . TYR C 2 85  ? 266.695 334.784 425.663 1.00 176.25 ? 89  TYR L CE2 1 
ATOM 2582 C CZ  . TYR C 2 85  ? 266.970 335.275 424.406 1.00 176.25 ? 89  TYR L CZ  1 
ATOM 2583 O OH  . TYR C 2 85  ? 266.288 336.373 423.938 1.00 176.25 ? 89  TYR L OH  1 
ATOM 2584 N N   . TYR C 2 86  ? 268.390 328.690 425.508 1.00 173.37 ? 90  TYR L N   1 
ATOM 2585 C CA  . TYR C 2 86  ? 268.841 327.327 425.265 1.00 173.37 ? 90  TYR L CA  1 
ATOM 2586 C C   . TYR C 2 86  ? 269.427 327.202 423.864 1.00 173.37 ? 90  TYR L C   1 
ATOM 2587 O O   . TYR C 2 86  ? 269.012 327.903 422.937 1.00 173.37 ? 90  TYR L O   1 
ATOM 2588 C CB  . TYR C 2 86  ? 267.692 326.323 425.421 1.00 173.37 ? 90  TYR L CB  1 
ATOM 2589 C CG  . TYR C 2 86  ? 267.376 325.932 426.847 1.00 173.37 ? 90  TYR L CG  1 
ATOM 2590 C CD1 . TYR C 2 86  ? 267.963 326.587 427.919 1.00 173.37 ? 90  TYR L CD1 1 
ATOM 2591 C CD2 . TYR C 2 86  ? 266.485 324.902 427.118 1.00 173.37 ? 90  TYR L CD2 1 
ATOM 2592 C CE1 . TYR C 2 86  ? 267.673 326.229 429.220 1.00 173.37 ? 90  TYR L CE1 1 
ATOM 2593 C CE2 . TYR C 2 86  ? 266.189 324.537 428.415 1.00 173.37 ? 90  TYR L CE2 1 
ATOM 2594 C CZ  . TYR C 2 86  ? 266.785 325.204 429.462 1.00 173.37 ? 90  TYR L CZ  1 
ATOM 2595 O OH  . TYR C 2 86  ? 266.494 324.844 430.757 1.00 173.37 ? 90  TYR L OH  1 
ATOM 2596 N N   . CYS C 2 87  ? 270.398 326.299 423.718 1.00 174.92 ? 91  CYS L N   1 
ATOM 2597 C CA  . CYS C 2 87  ? 270.973 325.952 422.425 1.00 174.92 ? 91  CYS L CA  1 
ATOM 2598 C C   . CYS C 2 87  ? 271.008 324.436 422.282 1.00 174.92 ? 91  CYS L C   1 
ATOM 2599 O O   . CYS C 2 87  ? 271.351 323.726 423.231 1.00 174.92 ? 91  CYS L O   1 
ATOM 2600 C CB  . CYS C 2 87  ? 272.387 326.538 422.254 1.00 174.92 ? 91  CYS L CB  1 
ATOM 2601 S SG  . CYS C 2 87  ? 273.617 325.981 423.466 1.00 174.92 ? 91  CYS L SG  1 
ATOM 2602 N N   . LEU C 2 88  ? 270.646 323.943 421.098 1.00 170.16 ? 92  LEU L N   1 
ATOM 2603 C CA  . LEU C 2 88  ? 270.592 322.507 420.862 1.00 170.16 ? 92  LEU L CA  1 
ATOM 2604 C C   . LEU C 2 88  ? 270.791 322.226 419.380 1.00 170.16 ? 92  LEU L C   1 
ATOM 2605 O O   . LEU C 2 88  ? 270.432 323.041 418.525 1.00 170.16 ? 92  LEU L O   1 
ATOM 2606 C CB  . LEU C 2 88  ? 269.261 321.916 421.354 1.00 170.16 ? 92  LEU L CB  1 
ATOM 2607 C CG  . LEU C 2 88  ? 267.946 322.397 420.725 1.00 170.16 ? 92  LEU L CG  1 
ATOM 2608 C CD1 . LEU C 2 88  ? 267.610 321.669 419.422 1.00 170.16 ? 92  LEU L CD1 1 
ATOM 2609 C CD2 . LEU C 2 88  ? 266.794 322.302 421.709 1.00 170.16 ? 92  LEU L CD2 1 
ATOM 2610 N N   . GLN C 2 89  ? 271.351 321.058 419.086 1.00 166.51 ? 93  GLN L N   1 
ATOM 2611 C CA  . GLN C 2 89  ? 271.580 320.604 417.723 1.00 166.51 ? 93  GLN L CA  1 
ATOM 2612 C C   . GLN C 2 89  ? 270.760 319.351 417.442 1.00 166.51 ? 93  GLN L C   1 
ATOM 2613 O O   . GLN C 2 89  ? 270.224 318.710 418.349 1.00 166.51 ? 93  GLN L O   1 
ATOM 2614 C CB  . GLN C 2 89  ? 273.069 320.334 417.480 1.00 166.51 ? 93  GLN L CB  1 
ATOM 2615 C CG  . GLN C 2 89  ? 273.650 319.209 418.322 1.00 166.51 ? 93  GLN L CG  1 
ATOM 2616 C CD  . GLN C 2 89  ? 273.541 317.856 417.648 1.00 166.51 ? 93  GLN L CD  1 
ATOM 2617 O OE1 . GLN C 2 89  ? 273.520 317.759 416.421 1.00 166.51 ? 93  GLN L OE1 1 
ATOM 2618 N NE2 . GLN C 2 89  ? 273.471 316.801 418.451 1.00 166.51 ? 93  GLN L NE2 1 
ATOM 2619 N N   . TYR C 2 90  ? 270.668 319.002 416.153 1.00 166.06 ? 94  TYR L N   1 
ATOM 2620 C CA  . TYR C 2 90  ? 269.944 317.800 415.759 1.00 166.06 ? 94  TYR L CA  1 
ATOM 2621 C C   . TYR C 2 90  ? 270.627 317.056 414.614 1.00 166.06 ? 94  TYR L C   1 
ATOM 2622 O O   . TYR C 2 90  ? 269.974 316.258 413.933 1.00 166.06 ? 94  TYR L O   1 
ATOM 2623 C CB  . TYR C 2 90  ? 268.506 318.136 415.354 1.00 166.06 ? 94  TYR L CB  1 
ATOM 2624 C CG  . TYR C 2 90  ? 268.388 319.345 414.457 1.00 166.06 ? 94  TYR L CG  1 
ATOM 2625 C CD1 . TYR C 2 90  ? 268.492 319.220 413.078 1.00 166.06 ? 94  TYR L CD1 1 
ATOM 2626 C CD2 . TYR C 2 90  ? 268.181 320.611 414.986 1.00 166.06 ? 94  TYR L CD2 1 
ATOM 2627 C CE1 . TYR C 2 90  ? 268.384 320.320 412.252 1.00 166.06 ? 94  TYR L CE1 1 
ATOM 2628 C CE2 . TYR C 2 90  ? 268.076 321.716 414.167 1.00 166.06 ? 94  TYR L CE2 1 
ATOM 2629 C CZ  . TYR C 2 90  ? 268.179 321.566 412.802 1.00 166.06 ? 94  TYR L CZ  1 
ATOM 2630 O OH  . TYR C 2 90  ? 268.074 322.665 411.983 1.00 166.06 ? 94  TYR L OH  1 
ATOM 2631 N N   . ALA C 2 91  ? 271.918 317.297 414.380 1.00 166.44 ? 95  ALA L N   1 
ATOM 2632 C CA  . ALA C 2 91  ? 272.604 316.637 413.275 1.00 166.44 ? 95  ALA L CA  1 
ATOM 2633 C C   . ALA C 2 91  ? 272.851 315.160 413.550 1.00 166.44 ? 95  ALA L C   1 
ATOM 2634 O O   . ALA C 2 91  ? 272.902 314.360 412.609 1.00 166.44 ? 95  ALA L O   1 
ATOM 2635 C CB  . ALA C 2 91  ? 273.928 317.343 412.980 1.00 166.44 ? 95  ALA L CB  1 
ATOM 2636 N N   . THR C 2 92  ? 273.007 314.784 414.813 1.00 160.78 ? 96  THR L N   1 
ATOM 2637 C CA  . THR C 2 92  ? 273.254 313.404 415.201 1.00 160.78 ? 96  THR L CA  1 
ATOM 2638 C C   . THR C 2 92  ? 271.989 312.816 415.816 1.00 160.78 ? 96  THR L C   1 
ATOM 2639 O O   . THR C 2 92  ? 271.191 313.530 416.430 1.00 160.78 ? 96  THR L O   1 
ATOM 2640 C CB  . THR C 2 92  ? 274.422 313.326 416.189 1.00 160.78 ? 96  THR L CB  1 
ATOM 2641 O OG1 . THR C 2 92  ? 275.549 314.021 415.643 1.00 160.78 ? 96  THR L OG1 1 
ATOM 2642 C CG2 . THR C 2 92  ? 274.831 311.884 416.432 1.00 160.78 ? 96  THR L CG2 1 
ATOM 2643 N N   . SER C 2 93  ? 271.804 311.507 415.630 1.00 154.82 ? 97  SER L N   1 
ATOM 2644 C CA  . SER C 2 93  ? 270.565 310.863 416.064 1.00 154.82 ? 97  SER L CA  1 
ATOM 2645 C C   . SER C 2 93  ? 270.280 311.059 417.549 1.00 154.82 ? 97  SER L C   1 
ATOM 2646 O O   . SER C 2 93  ? 269.139 311.416 417.889 1.00 154.82 ? 97  SER L O   1 
ATOM 2647 C CB  . SER C 2 93  ? 270.593 309.379 415.681 1.00 154.82 ? 97  SER L CB  1 
ATOM 2648 O OG  . SER C 2 93  ? 269.472 308.696 416.213 1.00 154.82 ? 97  SER L OG  1 
ATOM 2649 N N   . PRO C 2 94  ? 271.231 310.857 418.479 1.00 153.35 ? 98  PRO L N   1 
ATOM 2650 C CA  . PRO C 2 94  ? 270.973 311.235 419.876 1.00 153.35 ? 98  PRO L CA  1 
ATOM 2651 C C   . PRO C 2 94  ? 271.089 312.741 420.053 1.00 153.35 ? 98  PRO L C   1 
ATOM 2652 O O   . PRO C 2 94  ? 272.190 313.301 420.064 1.00 153.35 ? 98  PRO L O   1 
ATOM 2653 C CB  . PRO C 2 94  ? 272.065 310.479 420.649 1.00 153.35 ? 98  PRO L CB  1 
ATOM 2654 C CG  . PRO C 2 94  ? 272.576 309.444 419.702 1.00 153.35 ? 98  PRO L CG  1 
ATOM 2655 C CD  . PRO C 2 94  ? 272.481 310.089 418.367 1.00 153.35 ? 98  PRO L CD  1 
ATOM 2656 N N   . TYR C 2 95  ? 269.945 313.402 420.189 1.00 147.54 ? 99  TYR L N   1 
ATOM 2657 C CA  . TYR C 2 95  ? 269.911 314.840 420.397 1.00 147.54 ? 99  TYR L CA  1 
ATOM 2658 C C   . TYR C 2 95  ? 270.104 315.170 421.872 1.00 147.54 ? 99  TYR L C   1 
ATOM 2659 O O   . TYR C 2 95  ? 269.882 314.334 422.752 1.00 147.54 ? 99  TYR L O   1 
ATOM 2660 C CB  . TYR C 2 95  ? 268.587 315.417 419.897 1.00 147.54 ? 99  TYR L CB  1 
ATOM 2661 C CG  . TYR C 2 95  ? 267.395 314.533 420.192 1.00 147.54 ? 99  TYR L CG  1 
ATOM 2662 C CD1 . TYR C 2 95  ? 266.776 314.561 421.433 1.00 147.54 ? 99  TYR L CD1 1 
ATOM 2663 C CD2 . TYR C 2 95  ? 266.891 313.670 419.228 1.00 147.54 ? 99  TYR L CD2 1 
ATOM 2664 C CE1 . TYR C 2 95  ? 265.692 313.755 421.707 1.00 147.54 ? 99  TYR L CE1 1 
ATOM 2665 C CE2 . TYR C 2 95  ? 265.805 312.860 419.494 1.00 147.54 ? 99  TYR L CE2 1 
ATOM 2666 C CZ  . TYR C 2 95  ? 265.210 312.907 420.735 1.00 147.54 ? 99  TYR L CZ  1 
ATOM 2667 O OH  . TYR C 2 95  ? 264.129 312.103 421.005 1.00 147.54 ? 99  TYR L OH  1 
ATOM 2668 N N   . THR C 2 96  ? 270.528 316.403 422.137 1.00 158.93 ? 100 THR L N   1 
ATOM 2669 C CA  . THR C 2 96  ? 270.741 316.847 423.506 1.00 158.93 ? 100 THR L CA  1 
ATOM 2670 C C   . THR C 2 96  ? 270.563 318.355 423.585 1.00 158.93 ? 100 THR L C   1 
ATOM 2671 O O   . THR C 2 96  ? 270.625 319.064 422.577 1.00 158.93 ? 100 THR L O   1 
ATOM 2672 C CB  . THR C 2 96  ? 272.128 316.450 424.024 1.00 158.93 ? 100 THR L CB  1 
ATOM 2673 O OG1 . THR C 2 96  ? 272.155 316.556 425.452 1.00 158.93 ? 100 THR L OG1 1 
ATOM 2674 C CG2 . THR C 2 96  ? 273.193 317.358 423.438 1.00 158.93 ? 100 THR L CG2 1 
ATOM 2675 N N   . PHE C 2 97  ? 270.334 318.836 424.804 1.00 164.90 ? 101 PHE L N   1 
ATOM 2676 C CA  . PHE C 2 97  ? 270.165 320.255 425.063 1.00 164.90 ? 101 PHE L CA  1 
ATOM 2677 C C   . PHE C 2 97  ? 271.502 320.894 425.428 1.00 164.90 ? 101 PHE L C   1 
ATOM 2678 O O   . PHE C 2 97  ? 272.562 320.265 425.382 1.00 164.90 ? 101 PHE L O   1 
ATOM 2679 C CB  . PHE C 2 97  ? 269.150 320.481 426.183 1.00 164.90 ? 101 PHE L CB  1 
ATOM 2680 C CG  . PHE C 2 97  ? 267.726 320.249 425.774 1.00 164.90 ? 101 PHE L CG  1 
ATOM 2681 C CD1 . PHE C 2 97  ? 267.378 320.156 424.438 1.00 164.90 ? 101 PHE L CD1 1 
ATOM 2682 C CD2 . PHE C 2 97  ? 266.731 320.143 426.730 1.00 164.90 ? 101 PHE L CD2 1 
ATOM 2683 C CE1 . PHE C 2 97  ? 266.067 319.946 424.066 1.00 164.90 ? 101 PHE L CE1 1 
ATOM 2684 C CE2 . PHE C 2 97  ? 265.418 319.937 426.362 1.00 164.90 ? 101 PHE L CE2 1 
ATOM 2685 C CZ  . PHE C 2 97  ? 265.086 319.842 425.027 1.00 164.90 ? 101 PHE L CZ  1 
ATOM 2686 N N   . GLY C 2 98  ? 271.448 322.171 425.794 1.00 171.71 ? 102 GLY L N   1 
ATOM 2687 C CA  . GLY C 2 98  ? 272.596 322.859 426.347 1.00 171.71 ? 102 GLY L CA  1 
ATOM 2688 C C   . GLY C 2 98  ? 272.234 323.575 427.631 1.00 171.71 ? 102 GLY L C   1 
ATOM 2689 O O   . GLY C 2 98  ? 271.444 324.524 427.618 1.00 171.71 ? 102 GLY L O   1 
ATOM 2690 N N   . GLY C 2 99  ? 272.806 323.133 428.748 1.00 173.77 ? 103 GLY L N   1 
ATOM 2691 C CA  . GLY C 2 99  ? 272.443 323.697 430.038 1.00 173.77 ? 103 GLY L CA  1 
ATOM 2692 C C   . GLY C 2 99  ? 273.188 324.992 430.318 1.00 173.77 ? 103 GLY L C   1 
ATOM 2693 O O   . GLY C 2 99  ? 274.361 325.148 429.981 1.00 173.77 ? 103 GLY L O   1 
ATOM 2694 N N   . GLY C 2 100 ? 272.486 325.927 430.944 1.00 170.80 ? 104 GLY L N   1 
ATOM 2695 C CA  . GLY C 2 100 ? 273.053 327.206 431.319 1.00 170.80 ? 104 GLY L CA  1 
ATOM 2696 C C   . GLY C 2 100 ? 272.209 328.365 430.827 1.00 170.80 ? 104 GLY L C   1 
ATOM 2697 O O   . GLY C 2 100 ? 271.387 328.242 429.921 1.00 170.80 ? 104 GLY L O   1 
ATOM 2698 N N   . THR C 2 101 ? 272.440 329.513 431.455 1.00 166.19 ? 105 THR L N   1 
ATOM 2699 C CA  . THR C 2 101 ? 271.727 330.736 431.111 1.00 166.19 ? 105 THR L CA  1 
ATOM 2700 C C   . THR C 2 101 ? 272.133 331.241 429.731 1.00 166.19 ? 105 THR L C   1 
ATOM 2701 O O   . THR C 2 101 ? 271.519 330.887 428.725 1.00 166.19 ? 105 THR L O   1 
ATOM 2702 C CB  . THR C 2 101 ? 271.980 331.843 432.149 1.00 166.19 ? 105 THR L CB  1 
ATOM 2703 O OG1 . THR C 2 101 ? 271.849 331.302 433.469 1.00 166.19 ? 105 THR L OG1 1 
ATOM 2704 C CG2 . THR C 2 101 ? 270.990 332.978 431.970 1.00 166.19 ? 105 THR L CG2 1 
ATOM 2705 N N   . ILE D 3 1   ? 250.510 309.325 432.254 1.00 151.97 ? 23  ILE H N   1 
ATOM 2706 C CA  . ILE D 3 1   ? 250.100 309.236 430.859 1.00 151.97 ? 23  ILE H CA  1 
ATOM 2707 C C   . ILE D 3 1   ? 249.802 310.623 430.303 1.00 151.97 ? 23  ILE H C   1 
ATOM 2708 O O   . ILE D 3 1   ? 248.833 311.268 430.701 1.00 151.97 ? 23  ILE H O   1 
ATOM 2709 C CB  . ILE D 3 1   ? 248.883 308.307 430.694 1.00 151.97 ? 23  ILE H CB  1 
ATOM 2710 C CG1 . ILE D 3 1   ? 249.242 306.877 431.103 1.00 151.97 ? 23  ILE H CG1 1 
ATOM 2711 C CG2 . ILE D 3 1   ? 248.371 308.345 429.262 1.00 151.97 ? 23  ILE H CG2 1 
ATOM 2712 C CD1 . ILE D 3 1   ? 248.864 306.526 432.527 1.00 151.97 ? 23  ILE H CD1 1 
ATOM 2713 N N   . SER D 3 2   ? 250.645 311.079 429.382 1.00 150.89 ? 24  SER H N   1 
ATOM 2714 C CA  . SER D 3 2   ? 250.503 312.390 428.770 1.00 150.89 ? 24  SER H CA  1 
ATOM 2715 C C   . SER D 3 2   ? 250.001 312.261 427.337 1.00 150.89 ? 24  SER H C   1 
ATOM 2716 O O   . SER D 3 2   ? 250.248 311.260 426.659 1.00 150.89 ? 24  SER H O   1 
ATOM 2717 C CB  . SER D 3 2   ? 251.833 313.146 428.790 1.00 150.89 ? 24  SER H CB  1 
ATOM 2718 O OG  . SER D 3 2   ? 252.171 313.544 430.106 1.00 150.89 ? 24  SER H OG  1 
ATOM 2719 N N   . CYS D 3 3   ? 249.290 313.290 426.882 1.00 148.93 ? 25  CYS H N   1 
ATOM 2720 C CA  . CYS D 3 3   ? 248.754 313.308 425.529 1.00 148.93 ? 25  CYS H CA  1 
ATOM 2721 C C   . CYS D 3 3   ? 248.512 314.750 425.111 1.00 148.93 ? 25  CYS H C   1 
ATOM 2722 O O   . CYS D 3 3   ? 248.310 315.629 425.953 1.00 148.93 ? 25  CYS H O   1 
ATOM 2723 C CB  . CYS D 3 3   ? 247.456 312.502 425.431 1.00 148.93 ? 25  CYS H CB  1 
ATOM 2724 S SG  . CYS D 3 3   ? 246.090 313.180 426.402 1.00 148.93 ? 25  CYS H SG  1 
ATOM 2725 N N   . LYS D 3 4   ? 248.528 314.979 423.799 1.00 143.37 ? 26  LYS H N   1 
ATOM 2726 C CA  . LYS D 3 4   ? 248.261 316.301 423.251 1.00 143.37 ? 26  LYS H CA  1 
ATOM 2727 C C   . LYS D 3 4   ? 247.795 316.155 421.811 1.00 143.37 ? 26  LYS H C   1 
ATOM 2728 O O   . LYS D 3 4   ? 248.100 315.168 421.137 1.00 143.37 ? 26  LYS H O   1 
ATOM 2729 C CB  . LYS D 3 4   ? 249.496 317.205 423.329 1.00 143.37 ? 26  LYS H CB  1 
ATOM 2730 C CG  . LYS D 3 4   ? 249.189 318.644 423.710 1.00 143.37 ? 26  LYS H CG  1 
ATOM 2731 C CD  . LYS D 3 4   ? 248.847 318.766 425.186 1.00 143.37 ? 26  LYS H CD  1 
ATOM 2732 C CE  . LYS D 3 4   ? 248.878 320.215 425.638 1.00 143.37 ? 26  LYS H CE  1 
ATOM 2733 N NZ  . LYS D 3 4   ? 248.878 320.327 427.121 1.00 143.37 ? 26  LYS H NZ  1 
ATOM 2734 N N   . SER D 3 5   ? 247.055 317.159 421.348 1.00 142.16 ? 27  SER H N   1 
ATOM 2735 C CA  . SER D 3 5   ? 246.543 317.199 419.988 1.00 142.16 ? 27  SER H CA  1 
ATOM 2736 C C   . SER D 3 5   ? 246.892 318.541 419.359 1.00 142.16 ? 27  SER H C   1 
ATOM 2737 O O   . SER D 3 5   ? 247.112 319.537 420.052 1.00 142.16 ? 27  SER H O   1 
ATOM 2738 C CB  . SER D 3 5   ? 245.026 316.972 419.948 1.00 142.16 ? 27  SER H CB  1 
ATOM 2739 O OG  . SER D 3 5   ? 244.369 317.750 420.933 1.00 142.16 ? 27  SER H OG  1 
ATOM 2740 N N   . SER D 3 6   ? 246.940 318.556 418.029 1.00 134.57 ? 28  SER H N   1 
ATOM 2741 C CA  . SER D 3 6   ? 247.377 319.720 417.272 1.00 134.57 ? 28  SER H CA  1 
ATOM 2742 C C   . SER D 3 6   ? 246.377 320.018 416.160 1.00 134.57 ? 28  SER H C   1 
ATOM 2743 O O   . SER D 3 6   ? 245.344 319.356 416.027 1.00 134.57 ? 28  SER H O   1 
ATOM 2744 C CB  . SER D 3 6   ? 248.782 319.502 416.699 1.00 134.57 ? 28  SER H CB  1 
ATOM 2745 O OG  . SER D 3 6   ? 248.871 318.249 416.045 1.00 134.57 ? 28  SER H OG  1 
ATOM 2746 N N   . GLY D 3 7   ? 246.698 321.026 415.350 1.00 132.18 ? 29  GLY H N   1 
ATOM 2747 C CA  . GLY D 3 7   ? 245.805 321.469 414.297 1.00 132.18 ? 29  GLY H CA  1 
ATOM 2748 C C   . GLY D 3 7   ? 246.429 321.525 412.917 1.00 132.18 ? 29  GLY H C   1 
ATOM 2749 O O   . GLY D 3 7   ? 245.758 321.886 411.945 1.00 132.18 ? 29  GLY H O   1 
ATOM 2750 N N   . TYR D 3 8   ? 247.708 321.174 412.812 1.00 131.39 ? 30  TYR H N   1 
ATOM 2751 C CA  . TYR D 3 8   ? 248.396 321.145 411.530 1.00 131.39 ? 30  TYR H CA  1 
ATOM 2752 C C   . TYR D 3 8   ? 248.198 319.771 410.889 1.00 131.39 ? 30  TYR H C   1 
ATOM 2753 O O   . TYR D 3 8   ? 247.383 318.964 411.342 1.00 131.39 ? 30  TYR H O   1 
ATOM 2754 C CB  . TYR D 3 8   ? 249.872 321.488 411.716 1.00 131.39 ? 30  TYR H CB  1 
ATOM 2755 C CG  . TYR D 3 8   ? 250.666 320.397 412.396 1.00 131.39 ? 30  TYR H CG  1 
ATOM 2756 C CD1 . TYR D 3 8   ? 250.625 320.236 413.773 1.00 131.39 ? 30  TYR H CD1 1 
ATOM 2757 C CD2 . TYR D 3 8   ? 251.467 319.536 411.662 1.00 131.39 ? 30  TYR H CD2 1 
ATOM 2758 C CE1 . TYR D 3 8   ? 251.349 319.240 414.396 1.00 131.39 ? 30  TYR H CE1 1 
ATOM 2759 C CE2 . TYR D 3 8   ? 252.194 318.539 412.277 1.00 131.39 ? 30  TYR H CE2 1 
ATOM 2760 C CZ  . TYR D 3 8   ? 252.129 318.394 413.642 1.00 131.39 ? 30  TYR H CZ  1 
ATOM 2761 O OH  . TYR D 3 8   ? 252.854 317.401 414.258 1.00 131.39 ? 30  TYR H OH  1 
ATOM 2762 N N   . ALA D 3 9   ? 248.943 319.487 409.824 1.00 124.48 ? 31  ALA H N   1 
ATOM 2763 C CA  . ALA D 3 9   ? 248.875 318.181 409.171 1.00 124.48 ? 31  ALA H CA  1 
ATOM 2764 C C   . ALA D 3 9   ? 249.510 317.146 410.087 1.00 124.48 ? 31  ALA H C   1 
ATOM 2765 O O   . ALA D 3 9   ? 250.733 317.003 410.126 1.00 124.48 ? 31  ALA H O   1 
ATOM 2766 C CB  . ALA D 3 9   ? 249.579 318.218 407.820 1.00 124.48 ? 31  ALA H CB  1 
ATOM 2767 N N   . PHE D 3 10  ? 248.676 316.404 410.821 1.00 131.06 ? 32  PHE H N   1 
ATOM 2768 C CA  . PHE D 3 10  ? 249.199 315.489 411.831 1.00 131.06 ? 32  PHE H CA  1 
ATOM 2769 C C   . PHE D 3 10  ? 250.075 314.411 411.207 1.00 131.06 ? 32  PHE H C   1 
ATOM 2770 O O   . PHE D 3 10  ? 251.151 314.097 411.729 1.00 131.06 ? 32  PHE H O   1 
ATOM 2771 C CB  . PHE D 3 10  ? 248.056 314.855 412.620 1.00 131.06 ? 32  PHE H CB  1 
ATOM 2772 C CG  . PHE D 3 10  ? 248.514 314.087 413.822 1.00 131.06 ? 32  PHE H CG  1 
ATOM 2773 C CD1 . PHE D 3 10  ? 248.930 314.748 414.963 1.00 131.06 ? 32  PHE H CD1 1 
ATOM 2774 C CD2 . PHE D 3 10  ? 248.545 312.704 413.806 1.00 131.06 ? 32  PHE H CD2 1 
ATOM 2775 C CE1 . PHE D 3 10  ? 249.359 314.046 416.069 1.00 131.06 ? 32  PHE H CE1 1 
ATOM 2776 C CE2 . PHE D 3 10  ? 248.973 311.997 414.910 1.00 131.06 ? 32  PHE H CE2 1 
ATOM 2777 C CZ  . PHE D 3 10  ? 249.382 312.669 416.043 1.00 131.06 ? 32  PHE H CZ  1 
ATOM 2778 N N   . SER D 3 11  ? 249.637 313.834 410.093 1.00 125.67 ? 33  SER H N   1 
ATOM 2779 C CA  . SER D 3 11  ? 250.477 312.883 409.389 1.00 125.67 ? 33  SER H CA  1 
ATOM 2780 C C   . SER D 3 11  ? 251.632 313.614 408.707 1.00 125.67 ? 33  SER H C   1 
ATOM 2781 O O   . SER D 3 11  ? 251.615 314.836 408.534 1.00 125.67 ? 33  SER H O   1 
ATOM 2782 C CB  . SER D 3 11  ? 249.658 312.096 408.368 1.00 125.67 ? 33  SER H CB  1 
ATOM 2783 O OG  . SER D 3 11  ? 249.198 312.939 407.328 1.00 125.67 ? 33  SER H OG  1 
ATOM 2784 N N   . SER D 3 12  ? 252.652 312.844 408.328 1.00 125.01 ? 34  SER H N   1 
ATOM 2785 C CA  . SER D 3 12  ? 253.843 313.378 407.667 1.00 125.01 ? 34  SER H CA  1 
ATOM 2786 C C   . SER D 3 12  ? 254.553 314.404 408.549 1.00 125.01 ? 34  SER H C   1 
ATOM 2787 O O   . SER D 3 12  ? 254.792 315.545 408.149 1.00 125.01 ? 34  SER H O   1 
ATOM 2788 C CB  . SER D 3 12  ? 253.496 313.972 406.299 1.00 125.01 ? 34  SER H CB  1 
ATOM 2789 O OG  . SER D 3 12  ? 254.624 314.595 405.712 1.00 125.01 ? 34  SER H OG  1 
ATOM 2790 N N   . SER D 3 13  ? 254.891 313.985 409.766 1.00 128.20 ? 35  SER H N   1 
ATOM 2791 C CA  . SER D 3 13  ? 255.603 314.833 410.712 1.00 128.20 ? 35  SER H CA  1 
ATOM 2792 C C   . SER D 3 13  ? 256.184 313.949 411.806 1.00 128.20 ? 35  SER H C   1 
ATOM 2793 O O   . SER D 3 13  ? 256.047 312.726 411.781 1.00 128.20 ? 35  SER H O   1 
ATOM 2794 C CB  . SER D 3 13  ? 254.685 315.903 411.310 1.00 128.20 ? 35  SER H CB  1 
ATOM 2795 O OG  . SER D 3 13  ? 254.213 316.788 410.312 1.00 128.20 ? 35  SER H OG  1 
ATOM 2796 N N   . TRP D 3 14  ? 256.841 314.587 412.768 1.00 127.91 ? 36  TRP H N   1 
ATOM 2797 C CA  . TRP D 3 14  ? 257.303 313.923 413.977 1.00 127.91 ? 36  TRP H CA  1 
ATOM 2798 C C   . TRP D 3 14  ? 256.768 314.622 415.218 1.00 127.91 ? 36  TRP H C   1 
ATOM 2799 O O   . TRP D 3 14  ? 256.488 315.823 415.219 1.00 127.91 ? 36  TRP H O   1 
ATOM 2800 C CB  . TRP D 3 14  ? 258.834 313.855 414.045 1.00 127.91 ? 36  TRP H CB  1 
ATOM 2801 C CG  . TRP D 3 14  ? 259.443 312.753 413.240 1.00 127.91 ? 36  TRP H CG  1 
ATOM 2802 C CD1 . TRP D 3 14  ? 258.788 311.736 412.619 1.00 127.91 ? 36  TRP H CD1 1 
ATOM 2803 C CD2 . TRP D 3 14  ? 260.839 312.530 413.010 1.00 127.91 ? 36  TRP H CD2 1 
ATOM 2804 N NE1 . TRP D 3 14  ? 259.685 310.902 411.998 1.00 127.91 ? 36  TRP H NE1 1 
ATOM 2805 C CE2 . TRP D 3 14  ? 260.952 311.369 412.224 1.00 127.91 ? 36  TRP H CE2 1 
ATOM 2806 C CE3 . TRP D 3 14  ? 262.003 313.207 413.383 1.00 127.91 ? 36  TRP H CE3 1 
ATOM 2807 C CZ2 . TRP D 3 14  ? 262.181 310.868 411.805 1.00 127.91 ? 36  TRP H CZ2 1 
ATOM 2808 C CZ3 . TRP D 3 14  ? 263.223 312.709 412.965 1.00 127.91 ? 36  TRP H CZ3 1 
ATOM 2809 C CH2 . TRP D 3 14  ? 263.302 311.551 412.184 1.00 127.91 ? 36  TRP H CH2 1 
ATOM 2810 N N   . MET D 3 15  ? 256.632 313.836 416.283 1.00 136.37 ? 37  MET H N   1 
ATOM 2811 C CA  . MET D 3 15  ? 256.131 314.300 417.571 1.00 136.37 ? 37  MET H CA  1 
ATOM 2812 C C   . MET D 3 15  ? 257.248 314.121 418.592 1.00 136.37 ? 37  MET H C   1 
ATOM 2813 O O   . MET D 3 15  ? 257.441 313.020 419.119 1.00 136.37 ? 37  MET H O   1 
ATOM 2814 C CB  . MET D 3 15  ? 254.881 313.519 417.974 1.00 136.37 ? 37  MET H CB  1 
ATOM 2815 C CG  . MET D 3 15  ? 254.263 313.950 419.287 1.00 136.37 ? 37  MET H CG  1 
ATOM 2816 S SD  . MET D 3 15  ? 254.397 315.722 419.559 1.00 136.37 ? 37  MET H SD  1 
ATOM 2817 C CE  . MET D 3 15  ? 252.911 316.291 418.740 1.00 136.37 ? 37  MET H CE  1 
ATOM 2818 N N   . ASN D 3 16  ? 257.982 315.196 418.868 1.00 143.02 ? 38  ASN H N   1 
ATOM 2819 C CA  . ASN D 3 16  ? 259.123 315.154 419.772 1.00 143.02 ? 38  ASN H CA  1 
ATOM 2820 C C   . ASN D 3 16  ? 258.644 315.216 421.215 1.00 143.02 ? 38  ASN H C   1 
ATOM 2821 O O   . ASN D 3 16  ? 257.761 316.013 421.549 1.00 143.02 ? 38  ASN H O   1 
ATOM 2822 C CB  . ASN D 3 16  ? 260.096 316.303 419.498 1.00 143.02 ? 38  ASN H CB  1 
ATOM 2823 C CG  . ASN D 3 16  ? 261.029 316.018 418.338 1.00 143.02 ? 38  ASN H CG  1 
ATOM 2824 O OD1 . ASN D 3 16  ? 261.234 316.863 417.470 1.00 143.02 ? 38  ASN H OD1 1 
ATOM 2825 N ND2 . ASN D 3 16  ? 261.606 314.825 418.324 1.00 143.02 ? 38  ASN H ND2 1 
ATOM 2826 N N   . TRP D 3 17  ? 259.228 314.373 422.061 1.00 147.57 ? 39  TRP H N   1 
ATOM 2827 C CA  . TRP D 3 17  ? 258.947 314.353 423.493 1.00 147.57 ? 39  TRP H CA  1 
ATOM 2828 C C   . TRP D 3 17  ? 260.274 314.376 424.239 1.00 147.57 ? 39  TRP H C   1 
ATOM 2829 O O   . TRP D 3 17  ? 260.967 313.355 424.312 1.00 147.57 ? 39  TRP H O   1 
ATOM 2830 C CB  . TRP D 3 17  ? 258.123 313.125 423.870 1.00 147.57 ? 39  TRP H CB  1 
ATOM 2831 C CG  . TRP D 3 17  ? 256.658 313.351 423.772 1.00 147.57 ? 39  TRP H CG  1 
ATOM 2832 C CD1 . TRP D 3 17  ? 256.012 314.550 423.828 1.00 147.57 ? 39  TRP H CD1 1 
ATOM 2833 C CD2 . TRP D 3 17  ? 255.646 312.355 423.603 1.00 147.57 ? 39  TRP H CD2 1 
ATOM 2834 N NE1 . TRP D 3 17  ? 254.658 314.361 423.706 1.00 147.57 ? 39  TRP H NE1 1 
ATOM 2835 C CE2 . TRP D 3 17  ? 254.408 313.021 423.568 1.00 147.57 ? 39  TRP H CE2 1 
ATOM 2836 C CE3 . TRP D 3 17  ? 255.668 310.965 423.483 1.00 147.57 ? 39  TRP H CE3 1 
ATOM 2837 C CZ2 . TRP D 3 17  ? 253.203 312.345 423.412 1.00 147.57 ? 39  TRP H CZ2 1 
ATOM 2838 C CZ3 . TRP D 3 17  ? 254.471 310.294 423.328 1.00 147.57 ? 39  TRP H CZ3 1 
ATOM 2839 C CH2 . TRP D 3 17  ? 253.256 310.984 423.295 1.00 147.57 ? 39  TRP H CH2 1 
ATOM 2840 N N   . VAL D 3 18  ? 260.631 315.536 424.782 1.00 153.58 ? 40  VAL H N   1 
ATOM 2841 C CA  . VAL D 3 18  ? 261.871 315.704 425.530 1.00 153.58 ? 40  VAL H CA  1 
ATOM 2842 C C   . VAL D 3 18  ? 261.562 316.510 426.783 1.00 153.58 ? 40  VAL H C   1 
ATOM 2843 O O   . VAL D 3 18  ? 260.761 317.450 426.745 1.00 153.58 ? 40  VAL H O   1 
ATOM 2844 C CB  . VAL D 3 18  ? 262.964 316.403 424.692 1.00 153.58 ? 40  VAL H CB  1 
ATOM 2845 C CG1 . VAL D 3 18  ? 264.245 316.554 425.503 1.00 153.58 ? 40  VAL H CG1 1 
ATOM 2846 C CG2 . VAL D 3 18  ? 263.230 315.652 423.397 1.00 153.58 ? 40  VAL H CG2 1 
ATOM 2847 N N   . LYS D 3 19  ? 262.188 316.136 427.895 1.00 158.03 ? 41  LYS H N   1 
ATOM 2848 C CA  . LYS D 3 19  ? 262.058 316.892 429.134 1.00 158.03 ? 41  LYS H CA  1 
ATOM 2849 C C   . LYS D 3 19  ? 262.620 318.297 428.948 1.00 158.03 ? 41  LYS H C   1 
ATOM 2850 O O   . LYS D 3 19  ? 263.823 318.515 429.087 1.00 158.03 ? 41  LYS H O   1 
ATOM 2851 C CB  . LYS D 3 19  ? 262.775 316.174 430.283 1.00 158.03 ? 41  LYS H CB  1 
ATOM 2852 C CG  . LYS D 3 19  ? 262.262 316.526 431.677 1.00 158.03 ? 41  LYS H CG  1 
ATOM 2853 C CD  . LYS D 3 19  ? 262.825 317.848 432.181 1.00 158.03 ? 41  LYS H CD  1 
ATOM 2854 C CE  . LYS D 3 19  ? 262.277 318.204 433.551 1.00 158.03 ? 41  LYS H CE  1 
ATOM 2855 N NZ  . LYS D 3 19  ? 262.574 319.618 433.911 1.00 158.03 ? 41  LYS H NZ  1 
ATOM 2856 N N   . ILE D 3 29  ? 264.002 312.585 424.072 1.00 148.42 ? 51  ILE H N   1 
ATOM 2857 C CA  . ILE D 3 29  ? 263.852 311.211 424.523 1.00 148.42 ? 51  ILE H CA  1 
ATOM 2858 C C   . ILE D 3 29  ? 263.415 310.323 423.367 1.00 148.42 ? 51  ILE H C   1 
ATOM 2859 O O   . ILE D 3 29  ? 264.061 309.320 423.067 1.00 148.42 ? 51  ILE H O   1 
ATOM 2860 C CB  . ILE D 3 29  ? 262.857 311.114 425.688 1.00 148.42 ? 51  ILE H CB  1 
ATOM 2861 C CG1 . ILE D 3 29  ? 263.301 312.015 426.841 1.00 148.42 ? 51  ILE H CG1 1 
ATOM 2862 C CG2 . ILE D 3 29  ? 262.727 309.676 426.154 1.00 148.42 ? 51  ILE H CG2 1 
ATOM 2863 C CD1 . ILE D 3 29  ? 262.231 312.241 427.884 1.00 148.42 ? 51  ILE H CD1 1 
ATOM 2864 N N   . GLY D 3 30  ? 262.317 310.698 422.715 1.00 144.57 ? 52  GLY H N   1 
ATOM 2865 C CA  . GLY D 3 30  ? 261.787 309.899 421.627 1.00 144.57 ? 52  GLY H CA  1 
ATOM 2866 C C   . GLY D 3 30  ? 260.999 310.735 420.643 1.00 144.57 ? 52  GLY H C   1 
ATOM 2867 O O   . GLY D 3 30  ? 260.622 311.878 420.919 1.00 144.57 ? 52  GLY H O   1 
ATOM 2868 N N   . ARG D 3 31  ? 260.755 310.139 419.477 1.00 136.38 ? 53  ARG H N   1 
ATOM 2869 C CA  . ARG D 3 31  ? 259.995 310.779 418.415 1.00 136.38 ? 53  ARG H CA  1 
ATOM 2870 C C   . ARG D 3 31  ? 259.394 309.702 417.525 1.00 136.38 ? 53  ARG H C   1 
ATOM 2871 O O   . ARG D 3 31  ? 259.931 308.596 417.420 1.00 136.38 ? 53  ARG H O   1 
ATOM 2872 C CB  . ARG D 3 31  ? 260.876 311.736 417.605 1.00 136.38 ? 53  ARG H CB  1 
ATOM 2873 C CG  . ARG D 3 31  ? 262.085 311.087 416.955 1.00 136.38 ? 53  ARG H CG  1 
ATOM 2874 C CD  . ARG D 3 31  ? 263.085 312.148 416.521 1.00 136.38 ? 53  ARG H CD  1 
ATOM 2875 N NE  . ARG D 3 31  ? 264.250 311.584 415.850 1.00 136.38 ? 53  ARG H NE  1 
ATOM 2876 C CZ  . ARG D 3 31  ? 265.324 312.283 415.506 1.00 136.38 ? 53  ARG H CZ  1 
ATOM 2877 N NH1 . ARG D 3 31  ? 265.418 313.577 415.762 1.00 136.38 ? 53  ARG H NH1 1 
ATOM 2878 N NH2 . ARG D 3 31  ? 266.328 311.668 414.889 1.00 136.38 ? 53  ARG H NH2 1 
ATOM 2879 N N   . ILE D 3 32  ? 258.273 310.030 416.888 1.00 130.11 ? 54  ILE H N   1 
ATOM 2880 C CA  . ILE D 3 32  ? 257.507 309.059 416.116 1.00 130.11 ? 54  ILE H CA  1 
ATOM 2881 C C   . ILE D 3 32  ? 256.967 309.711 414.851 1.00 130.11 ? 54  ILE H C   1 
ATOM 2882 O O   . ILE D 3 32  ? 256.645 310.904 414.837 1.00 130.11 ? 54  ILE H O   1 
ATOM 2883 C CB  . ILE D 3 32  ? 256.360 308.453 416.953 1.00 130.11 ? 54  ILE H CB  1 
ATOM 2884 C CG1 . ILE D 3 32  ? 255.767 307.231 416.250 1.00 130.11 ? 54  ILE H CG1 1 
ATOM 2885 C CG2 . ILE D 3 32  ? 255.289 309.490 417.243 1.00 130.11 ? 54  ILE H CG2 1 
ATOM 2886 C CD1 . ILE D 3 32  ? 256.717 306.071 416.134 1.00 130.11 ? 54  ILE H CD1 1 
ATOM 2887 N N   . TYR D 3 33  ? 256.889 308.921 413.781 1.00 124.40 ? 55  TYR H N   1 
ATOM 2888 C CA  . TYR D 3 33  ? 256.226 309.317 412.550 1.00 124.40 ? 55  TYR H CA  1 
ATOM 2889 C C   . TYR D 3 33  ? 254.847 308.680 412.540 1.00 124.40 ? 55  TYR H C   1 
ATOM 2890 O O   . TYR D 3 33  ? 254.757 307.444 412.482 1.00 124.40 ? 55  TYR H O   1 
ATOM 2891 C CB  . TYR D 3 33  ? 257.040 308.855 411.346 1.00 124.40 ? 55  TYR H CB  1 
ATOM 2892 C CG  . TYR D 3 33  ? 256.790 309.592 410.048 1.00 124.40 ? 55  TYR H CG  1 
ATOM 2893 C CD1 . TYR D 3 33  ? 257.358 310.835 409.812 1.00 124.40 ? 55  TYR H CD1 1 
ATOM 2894 C CD2 . TYR D 3 33  ? 256.020 309.029 409.044 1.00 124.40 ? 55  TYR H CD2 1 
ATOM 2895 C CE1 . TYR D 3 33  ? 257.147 311.505 408.623 1.00 124.40 ? 55  TYR H CE1 1 
ATOM 2896 C CE2 . TYR D 3 33  ? 255.802 309.690 407.852 1.00 124.40 ? 55  TYR H CE2 1 
ATOM 2897 C CZ  . TYR D 3 33  ? 256.368 310.927 407.647 1.00 124.40 ? 55  TYR H CZ  1 
ATOM 2898 O OH  . TYR D 3 33  ? 256.154 311.586 406.459 1.00 124.40 ? 55  TYR H OH  1 
ATOM 2899 N N   . PRO D 3 34  ? 253.758 309.453 412.602 1.00 125.93 ? 56  PRO H N   1 
ATOM 2900 C CA  . PRO D 3 34  ? 252.447 308.844 412.880 1.00 125.93 ? 56  PRO H CA  1 
ATOM 2901 C C   . PRO D 3 34  ? 252.007 307.819 411.851 1.00 125.93 ? 56  PRO H C   1 
ATOM 2902 O O   . PRO D 3 34  ? 251.329 306.852 412.216 1.00 125.93 ? 56  PRO H O   1 
ATOM 2903 C CB  . PRO D 3 34  ? 251.501 310.051 412.916 1.00 125.93 ? 56  PRO H CB  1 
ATOM 2904 C CG  . PRO D 3 34  ? 252.154 311.059 412.059 1.00 125.93 ? 56  PRO H CG  1 
ATOM 2905 C CD  . PRO D 3 34  ? 253.637 310.864 412.204 1.00 125.93 ? 56  PRO H CD  1 
ATOM 2906 N N   . GLU D 3 35  ? 252.363 307.991 410.585 1.00 114.76 ? 57  GLU H N   1 
ATOM 2907 C CA  . GLU D 3 35  ? 252.057 307.006 409.559 1.00 114.76 ? 57  GLU H CA  1 
ATOM 2908 C C   . GLU D 3 35  ? 253.266 306.105 409.359 1.00 114.76 ? 57  GLU H C   1 
ATOM 2909 O O   . GLU D 3 35  ? 254.391 306.587 409.210 1.00 114.76 ? 57  GLU H O   1 
ATOM 2910 C CB  . GLU D 3 35  ? 251.673 307.682 408.243 1.00 114.76 ? 57  GLU H CB  1 
ATOM 2911 C CG  . GLU D 3 35  ? 251.600 306.735 407.061 1.00 114.76 ? 57  GLU H CG  1 
ATOM 2912 C CD  . GLU D 3 35  ? 251.609 307.464 405.736 1.00 114.76 ? 57  GLU H CD  1 
ATOM 2913 O OE1 . GLU D 3 35  ? 251.607 308.712 405.744 1.00 114.76 ? 57  GLU H OE1 1 
ATOM 2914 O OE2 . GLU D 3 35  ? 251.618 306.789 404.686 1.00 114.76 ? 57  GLU H OE2 1 
ATOM 2915 N N   . ASN D 3 36  ? 253.029 304.795 409.358 1.00 122.08 ? 58  ASN H N   1 
ATOM 2916 C CA  . ASN D 3 36  ? 254.101 303.804 409.360 1.00 122.08 ? 58  ASN H CA  1 
ATOM 2917 C C   . ASN D 3 36  ? 255.052 304.071 410.526 1.00 122.08 ? 58  ASN H C   1 
ATOM 2918 O O   . ASN D 3 36  ? 256.228 304.396 410.353 1.00 122.08 ? 58  ASN H O   1 
ATOM 2919 C CB  . ASN D 3 36  ? 254.844 303.794 408.020 1.00 122.08 ? 58  ASN H CB  1 
ATOM 2920 C CG  . ASN D 3 36  ? 255.826 302.643 407.902 1.00 122.08 ? 58  ASN H CG  1 
ATOM 2921 O OD1 . ASN D 3 36  ? 255.988 301.848 408.827 1.00 122.08 ? 58  ASN H OD1 1 
ATOM 2922 N ND2 . ASN D 3 36  ? 256.492 302.552 406.757 1.00 122.08 ? 58  ASN H ND2 1 
ATOM 2923 N N   . GLY D 3 37  ? 254.501 303.945 411.731 1.00 124.52 ? 59  GLY H N   1 
ATOM 2924 C CA  . GLY D 3 37  ? 255.200 304.305 412.949 1.00 124.52 ? 59  GLY H CA  1 
ATOM 2925 C C   . GLY D 3 37  ? 256.540 303.631 413.148 1.00 124.52 ? 59  GLY H C   1 
ATOM 2926 O O   . GLY D 3 37  ? 256.612 302.421 413.379 1.00 124.52 ? 59  GLY H O   1 
ATOM 2927 N N   . GLU D 3 38  ? 257.612 304.413 413.061 1.00 130.69 ? 60  GLU H N   1 
ATOM 2928 C CA  . GLU D 3 38  ? 258.970 303.946 413.327 1.00 130.69 ? 60  GLU H CA  1 
ATOM 2929 C C   . GLU D 3 38  ? 259.539 304.804 414.454 1.00 130.69 ? 60  GLU H C   1 
ATOM 2930 O O   . GLU D 3 38  ? 259.848 305.984 414.264 1.00 130.69 ? 60  GLU H O   1 
ATOM 2931 C CB  . GLU D 3 38  ? 259.826 303.987 412.059 1.00 130.69 ? 60  GLU H CB  1 
ATOM 2932 C CG  . GLU D 3 38  ? 259.931 305.343 411.379 1.00 130.69 ? 60  GLU H CG  1 
ATOM 2933 C CD  . GLU D 3 38  ? 260.243 305.228 409.903 1.00 130.69 ? 60  GLU H CD  1 
ATOM 2934 O OE1 . GLU D 3 38  ? 259.691 304.319 409.247 1.00 130.69 ? 60  GLU H OE1 1 
ATOM 2935 O OE2 . GLU D 3 38  ? 261.040 306.046 409.398 1.00 130.69 ? 60  GLU H OE2 1 
ATOM 2936 N N   . THR D 3 39  ? 259.647 304.217 415.640 1.00 137.54 ? 61  THR H N   1 
ATOM 2937 C CA  . THR D 3 39  ? 260.064 304.977 416.807 1.00 137.54 ? 61  THR H CA  1 
ATOM 2938 C C   . THR D 3 39  ? 261.574 305.181 416.819 1.00 137.54 ? 61  THR H C   1 
ATOM 2939 O O   . THR D 3 39  ? 262.330 304.468 416.154 1.00 137.54 ? 61  THR H O   1 
ATOM 2940 C CB  . THR D 3 39  ? 259.625 304.275 418.089 1.00 137.54 ? 61  THR H CB  1 
ATOM 2941 O OG1 . THR D 3 39  ? 259.895 305.123 419.210 1.00 137.54 ? 61  THR H OG1 1 
ATOM 2942 C CG2 . THR D 3 39  ? 260.372 302.962 418.261 1.00 137.54 ? 61  THR H CG2 1 
ATOM 2943 N N   . ASN D 3 40  ? 262.007 306.183 417.579 1.00 136.51 ? 62  ASN H N   1 
ATOM 2944 C CA  . ASN D 3 40  ? 263.419 306.458 417.794 1.00 136.51 ? 62  ASN H CA  1 
ATOM 2945 C C   . ASN D 3 40  ? 263.670 306.656 419.280 1.00 136.51 ? 62  ASN H C   1 
ATOM 2946 O O   . ASN D 3 40  ? 262.974 307.435 419.938 1.00 136.51 ? 62  ASN H O   1 
ATOM 2947 C CB  . ASN D 3 40  ? 263.873 307.698 417.018 1.00 136.51 ? 62  ASN H CB  1 
ATOM 2948 C CG  . ASN D 3 40  ? 263.837 307.491 415.521 1.00 136.51 ? 62  ASN H CG  1 
ATOM 2949 O OD1 . ASN D 3 40  ? 264.116 306.400 415.027 1.00 136.51 ? 62  ASN H OD1 1 
ATOM 2950 N ND2 . ASN D 3 40  ? 263.494 308.543 414.788 1.00 136.51 ? 62  ASN H ND2 1 
ATOM 2951 N N   . TYR D 3 41  ? 264.664 305.947 419.804 1.00 144.71 ? 63  TYR H N   1 
ATOM 2952 C CA  . TYR D 3 41  ? 265.065 306.059 421.198 1.00 144.71 ? 63  TYR H CA  1 
ATOM 2953 C C   . TYR D 3 41  ? 266.489 306.583 421.275 1.00 144.71 ? 63  TYR H C   1 
ATOM 2954 O O   . TYR D 3 41  ? 267.387 306.070 420.600 1.00 144.71 ? 63  TYR H O   1 
ATOM 2955 C CB  . TYR D 3 41  ? 264.961 304.711 421.925 1.00 144.71 ? 63  TYR H CB  1 
ATOM 2956 C CG  . TYR D 3 41  ? 263.569 304.120 421.958 1.00 144.71 ? 63  TYR H CG  1 
ATOM 2957 C CD1 . TYR D 3 41  ? 262.449 304.916 421.771 1.00 144.71 ? 63  TYR H CD1 1 
ATOM 2958 C CD2 . TYR D 3 41  ? 263.377 302.761 422.169 1.00 144.71 ? 63  TYR H CD2 1 
ATOM 2959 C CE1 . TYR D 3 41  ? 261.180 304.381 421.804 1.00 144.71 ? 63  TYR H CE1 1 
ATOM 2960 C CE2 . TYR D 3 41  ? 262.109 302.215 422.200 1.00 144.71 ? 63  TYR H CE2 1 
ATOM 2961 C CZ  . TYR D 3 41  ? 261.014 303.031 422.015 1.00 144.71 ? 63  TYR H CZ  1 
ATOM 2962 O OH  . TYR D 3 41  ? 259.747 302.496 422.044 1.00 144.71 ? 63  TYR H OH  1 
ATOM 2963 N N   . ASN D 3 42  ? 266.689 307.607 422.100 1.00 151.07 ? 64  ASN H N   1 
ATOM 2964 C CA  . ASN D 3 42  ? 267.995 308.215 422.288 1.00 151.07 ? 64  ASN H CA  1 
ATOM 2965 C C   . ASN D 3 42  ? 268.230 308.409 423.779 1.00 151.07 ? 64  ASN H C   1 
ATOM 2966 O O   . ASN D 3 42  ? 267.394 308.051 424.613 1.00 151.07 ? 64  ASN H O   1 
ATOM 2967 C CB  . ASN D 3 42  ? 268.105 309.542 421.530 1.00 151.07 ? 64  ASN H CB  1 
ATOM 2968 C CG  . ASN D 3 42  ? 267.935 309.373 420.034 1.00 151.07 ? 64  ASN H CG  1 
ATOM 2969 O OD1 . ASN D 3 42  ? 266.984 309.887 419.444 1.00 151.07 ? 64  ASN H OD1 1 
ATOM 2970 N ND2 . ASN D 3 42  ? 268.858 308.650 419.410 1.00 151.07 ? 64  ASN H ND2 1 
ATOM 2971 N N   . GLY D 3 43  ? 269.379 308.990 424.113 1.00 151.80 ? 65  GLY H N   1 
ATOM 2972 C CA  . GLY D 3 43  ? 269.736 309.190 425.502 1.00 151.80 ? 65  GLY H CA  1 
ATOM 2973 C C   . GLY D 3 43  ? 269.890 307.880 426.244 1.00 151.80 ? 65  GLY H C   1 
ATOM 2974 O O   . GLY D 3 43  ? 270.862 307.148 426.040 1.00 151.80 ? 65  GLY H O   1 
ATOM 2975 N N   . LYS D 3 44  ? 268.927 307.574 427.107 1.00 153.41 ? 66  LYS H N   1 
ATOM 2976 C CA  . LYS D 3 44  ? 268.946 306.344 427.885 1.00 153.41 ? 66  LYS H CA  1 
ATOM 2977 C C   . LYS D 3 44  ? 268.450 305.182 427.024 1.00 153.41 ? 66  LYS H C   1 
ATOM 2978 O O   . LYS D 3 44  ? 268.307 305.289 425.803 1.00 153.41 ? 66  LYS H O   1 
ATOM 2979 C CB  . LYS D 3 44  ? 268.110 306.512 429.151 1.00 153.41 ? 66  LYS H CB  1 
ATOM 2980 C CG  . LYS D 3 44  ? 266.619 306.662 428.890 1.00 153.41 ? 66  LYS H CG  1 
ATOM 2981 C CD  . LYS D 3 44  ? 265.930 307.409 430.018 1.00 153.41 ? 66  LYS H CD  1 
ATOM 2982 C CE  . LYS D 3 44  ? 266.013 308.912 429.816 1.00 153.41 ? 66  LYS H CE  1 
ATOM 2983 N NZ  . LYS D 3 44  ? 265.284 309.345 428.592 1.00 153.41 ? 66  LYS H NZ  1 
ATOM 2984 N N   . PHE D 3 45  ? 268.174 304.051 427.670 1.00 161.75 ? 67  PHE H N   1 
ATOM 2985 C CA  . PHE D 3 45  ? 267.616 302.875 427.013 1.00 161.75 ? 67  PHE H CA  1 
ATOM 2986 C C   . PHE D 3 45  ? 266.127 303.097 426.781 1.00 161.75 ? 67  PHE H C   1 
ATOM 2987 O O   . PHE D 3 45  ? 265.654 304.237 426.837 1.00 161.75 ? 67  PHE H O   1 
ATOM 2988 C CB  . PHE D 3 45  ? 267.862 301.623 427.863 1.00 161.75 ? 67  PHE H CB  1 
ATOM 2989 C CG  . PHE D 3 45  ? 267.854 300.335 427.081 1.00 161.75 ? 67  PHE H CG  1 
ATOM 2990 C CD1 . PHE D 3 45  ? 268.809 300.089 426.110 1.00 161.75 ? 67  PHE H CD1 1 
ATOM 2991 C CD2 . PHE D 3 45  ? 266.898 299.363 427.333 1.00 161.75 ? 67  PHE H CD2 1 
ATOM 2992 C CE1 . PHE D 3 45  ? 268.805 298.903 425.397 1.00 161.75 ? 67  PHE H CE1 1 
ATOM 2993 C CE2 . PHE D 3 45  ? 266.889 298.176 426.623 1.00 161.75 ? 67  PHE H CE2 1 
ATOM 2994 C CZ  . PHE D 3 45  ? 267.844 297.946 425.655 1.00 161.75 ? 67  PHE H CZ  1 
ATOM 2995 N N   . LYS D 3 46  ? 265.387 302.025 426.484 1.00 159.65 ? 68  LYS H N   1 
ATOM 2996 C CA  . LYS D 3 46  ? 263.935 302.132 426.381 1.00 159.65 ? 68  LYS H CA  1 
ATOM 2997 C C   . LYS D 3 46  ? 263.360 302.818 427.613 1.00 159.65 ? 68  LYS H C   1 
ATOM 2998 O O   . LYS D 3 46  ? 262.493 303.693 427.506 1.00 159.65 ? 68  LYS H O   1 
ATOM 2999 C CB  . LYS D 3 46  ? 263.321 300.743 426.197 1.00 159.65 ? 68  LYS H CB  1 
ATOM 3000 C CG  . LYS D 3 46  ? 263.863 299.979 424.999 1.00 159.65 ? 68  LYS H CG  1 
ATOM 3001 C CD  . LYS D 3 46  ? 263.367 298.542 424.989 1.00 159.65 ? 68  LYS H CD  1 
ATOM 3002 C CE  . LYS D 3 46  ? 264.005 297.744 423.862 1.00 159.65 ? 68  LYS H CE  1 
ATOM 3003 N NZ  . LYS D 3 46  ? 263.588 296.315 423.883 1.00 159.65 ? 68  LYS H NZ  1 
ATOM 3004 N N   . GLY D 3 47  ? 263.851 302.442 428.791 1.00 163.96 ? 69  GLY H N   1 
ATOM 3005 C CA  . GLY D 3 47  ? 263.562 303.196 430.000 1.00 163.96 ? 69  GLY H CA  1 
ATOM 3006 C C   . GLY D 3 47  ? 262.081 303.270 430.302 1.00 163.96 ? 69  GLY H C   1 
ATOM 3007 O O   . GLY D 3 47  ? 261.365 302.262 430.296 1.00 163.96 ? 69  GLY H O   1 
ATOM 3008 N N   . LYS D 3 48  ? 261.610 304.486 430.569 1.00 170.53 ? 70  LYS H N   1 
ATOM 3009 C CA  . LYS D 3 48  ? 260.240 304.720 430.998 1.00 170.53 ? 70  LYS H CA  1 
ATOM 3010 C C   . LYS D 3 48  ? 259.368 305.336 429.915 1.00 170.53 ? 70  LYS H C   1 
ATOM 3011 O O   . LYS D 3 48  ? 258.151 305.438 430.105 1.00 170.53 ? 70  LYS H O   1 
ATOM 3012 C CB  . LYS D 3 48  ? 260.223 305.635 432.230 1.00 170.53 ? 70  LYS H CB  1 
ATOM 3013 C CG  . LYS D 3 48  ? 260.541 304.951 433.549 1.00 170.53 ? 70  LYS H CG  1 
ATOM 3014 C CD  . LYS D 3 48  ? 262.034 304.733 433.724 1.00 170.53 ? 70  LYS H CD  1 
ATOM 3015 C CE  . LYS D 3 48  ? 262.756 306.057 433.910 1.00 170.53 ? 70  LYS H CE  1 
ATOM 3016 N NZ  . LYS D 3 48  ? 264.210 305.875 434.163 1.00 170.53 ? 70  LYS H NZ  1 
ATOM 3017 N N   . ALA D 3 49  ? 259.944 305.743 428.788 1.00 167.23 ? 71  ALA H N   1 
ATOM 3018 C CA  . ALA D 3 49  ? 259.241 306.599 427.841 1.00 167.23 ? 71  ALA H CA  1 
ATOM 3019 C C   . ALA D 3 49  ? 259.176 305.973 426.457 1.00 167.23 ? 71  ALA H C   1 
ATOM 3020 O O   . ALA D 3 49  ? 259.345 306.654 425.442 1.00 167.23 ? 71  ALA H O   1 
ATOM 3021 C CB  . ALA D 3 49  ? 259.890 307.979 427.774 1.00 167.23 ? 71  ALA H CB  1 
ATOM 3022 N N   . THR D 3 50  ? 258.930 304.669 426.382 1.00 159.88 ? 72  THR H N   1 
ATOM 3023 C CA  . THR D 3 50  ? 258.536 304.087 425.108 1.00 159.88 ? 72  THR H CA  1 
ATOM 3024 C C   . THR D 3 50  ? 257.120 304.541 424.771 1.00 159.88 ? 72  THR H C   1 
ATOM 3025 O O   . THR D 3 50  ? 256.259 304.651 425.650 1.00 159.88 ? 72  THR H O   1 
ATOM 3026 C CB  . THR D 3 50  ? 258.642 302.561 425.147 1.00 159.88 ? 72  THR H CB  1 
ATOM 3027 O OG1 . THR D 3 50  ? 258.409 302.028 423.837 1.00 159.88 ? 72  THR H OG1 1 
ATOM 3028 C CG2 . THR D 3 50  ? 257.662 301.957 426.136 1.00 159.88 ? 72  THR H CG2 1 
ATOM 3029 N N   . LEU D 3 51  ? 256.883 304.836 423.496 1.00 149.87 ? 73  LEU H N   1 
ATOM 3030 C CA  . LEU D 3 51  ? 255.718 305.626 423.130 1.00 149.87 ? 73  LEU H CA  1 
ATOM 3031 C C   . LEU D 3 51  ? 255.028 305.032 421.911 1.00 149.87 ? 73  LEU H C   1 
ATOM 3032 O O   . LEU D 3 51  ? 255.595 304.214 421.181 1.00 149.87 ? 73  LEU H O   1 
ATOM 3033 C CB  . LEU D 3 51  ? 256.116 307.089 422.884 1.00 149.87 ? 73  LEU H CB  1 
ATOM 3034 C CG  . LEU D 3 51  ? 257.117 307.405 421.764 1.00 149.87 ? 73  LEU H CG  1 
ATOM 3035 C CD1 . LEU D 3 51  ? 256.459 307.505 420.394 1.00 149.87 ? 73  LEU H CD1 1 
ATOM 3036 C CD2 . LEU D 3 51  ? 257.901 308.670 422.079 1.00 149.87 ? 73  LEU H CD2 1 
ATOM 3037 N N   . THR D 3 52  ? 253.786 305.465 421.705 1.00 145.06 ? 74  THR H N   1 
ATOM 3038 C CA  . THR D 3 52  ? 252.966 305.075 420.570 1.00 145.06 ? 74  THR H CA  1 
ATOM 3039 C C   . THR D 3 52  ? 252.322 306.319 419.971 1.00 145.06 ? 74  THR H C   1 
ATOM 3040 O O   . THR D 3 52  ? 252.459 307.428 420.492 1.00 145.06 ? 74  THR H O   1 
ATOM 3041 C CB  . THR D 3 52  ? 251.885 304.066 420.976 1.00 145.06 ? 74  THR H CB  1 
ATOM 3042 O OG1 . THR D 3 52  ? 251.215 303.584 419.805 1.00 145.06 ? 74  THR H OG1 1 
ATOM 3043 C CG2 . THR D 3 52  ? 250.872 304.722 421.900 1.00 145.06 ? 74  THR H CG2 1 
ATOM 3044 N N   . ALA D 3 53  ? 251.608 306.126 418.864 1.00 145.17 ? 75  ALA H N   1 
ATOM 3045 C CA  . ALA D 3 53  ? 250.955 307.236 418.186 1.00 145.17 ? 75  ALA H CA  1 
ATOM 3046 C C   . ALA D 3 53  ? 249.692 306.745 417.494 1.00 145.17 ? 75  ALA H C   1 
ATOM 3047 O O   . ALA D 3 53  ? 249.610 305.593 417.061 1.00 145.17 ? 75  ALA H O   1 
ATOM 3048 C CB  . ALA D 3 53  ? 251.890 307.899 417.169 1.00 145.17 ? 75  ALA H CB  1 
ATOM 3049 N N   . ASP D 3 54  ? 248.709 307.637 417.395 1.00 143.88 ? 76  ASP H N   1 
ATOM 3050 C CA  . ASP D 3 54  ? 247.451 307.370 416.707 1.00 143.88 ? 76  ASP H CA  1 
ATOM 3051 C C   . ASP D 3 54  ? 247.249 308.440 415.645 1.00 143.88 ? 76  ASP H C   1 
ATOM 3052 O O   . ASP D 3 54  ? 247.117 309.625 415.972 1.00 143.88 ? 76  ASP H O   1 
ATOM 3053 C CB  . ASP D 3 54  ? 246.277 307.357 417.690 1.00 143.88 ? 76  ASP H CB  1 
ATOM 3054 C CG  . ASP D 3 54  ? 244.943 307.065 417.017 1.00 143.88 ? 76  ASP H CG  1 
ATOM 3055 O OD1 . ASP D 3 54  ? 244.916 306.799 415.796 1.00 143.88 ? 76  ASP H OD1 1 
ATOM 3056 O OD2 . ASP D 3 54  ? 243.910 307.102 417.718 1.00 143.88 ? 76  ASP H OD2 1 
ATOM 3057 N N   . LYS D 3 55  ? 247.215 308.023 414.379 1.00 139.90 ? 77  LYS H N   1 
ATOM 3058 C CA  . LYS D 3 55  ? 247.007 308.972 413.293 1.00 139.90 ? 77  LYS H CA  1 
ATOM 3059 C C   . LYS D 3 55  ? 245.552 309.408 413.179 1.00 139.90 ? 77  LYS H C   1 
ATOM 3060 O O   . LYS D 3 55  ? 245.281 310.552 412.799 1.00 139.90 ? 77  LYS H O   1 
ATOM 3061 C CB  . LYS D 3 55  ? 247.479 308.368 411.969 1.00 139.90 ? 77  LYS H CB  1 
ATOM 3062 C CG  . LYS D 3 55  ? 246.892 307.001 411.664 1.00 139.90 ? 77  LYS H CG  1 
ATOM 3063 C CD  . LYS D 3 55  ? 247.596 306.349 410.488 1.00 139.90 ? 77  LYS H CD  1 
ATOM 3064 C CE  . LYS D 3 55  ? 247.356 307.127 409.207 1.00 139.90 ? 77  LYS H CE  1 
ATOM 3065 N NZ  . LYS D 3 55  ? 245.944 307.584 409.094 1.00 139.90 ? 77  LYS H NZ  1 
ATOM 3066 N N   . SER D 3 56  ? 244.610 308.517 413.495 1.00 142.88 ? 78  SER H N   1 
ATOM 3067 C CA  . SER D 3 56  ? 243.196 308.845 413.343 1.00 142.88 ? 78  SER H CA  1 
ATOM 3068 C C   . SER D 3 56  ? 242.768 309.949 414.304 1.00 142.88 ? 78  SER H C   1 
ATOM 3069 O O   . SER D 3 56  ? 242.048 310.874 413.912 1.00 142.88 ? 78  SER H O   1 
ATOM 3070 C CB  . SER D 3 56  ? 242.348 307.592 413.553 1.00 142.88 ? 78  SER H CB  1 
ATOM 3071 O OG  . SER D 3 56  ? 242.484 307.103 414.876 1.00 142.88 ? 78  SER H OG  1 
ATOM 3072 N N   . SER D 3 57  ? 243.200 309.871 415.560 1.00 146.24 ? 79  SER H N   1 
ATOM 3073 C CA  . SER D 3 57  ? 242.770 310.821 416.578 1.00 146.24 ? 79  SER H CA  1 
ATOM 3074 C C   . SER D 3 57  ? 243.623 312.080 416.623 1.00 146.24 ? 79  SER H C   1 
ATOM 3075 O O   . SER D 3 57  ? 243.317 312.982 417.410 1.00 146.24 ? 79  SER H O   1 
ATOM 3076 C CB  . SER D 3 57  ? 242.774 310.152 417.954 1.00 146.24 ? 79  SER H CB  1 
ATOM 3077 O OG  . SER D 3 57  ? 244.088 309.790 418.339 1.00 146.24 ? 79  SER H OG  1 
ATOM 3078 N N   . ARG D 3 58  ? 244.675 312.158 415.807 1.00 141.13 ? 80  ARG H N   1 
ATOM 3079 C CA  . ARG D 3 58  ? 245.565 313.317 415.758 1.00 141.13 ? 80  ARG H CA  1 
ATOM 3080 C C   . ARG D 3 58  ? 246.171 313.604 417.134 1.00 141.13 ? 80  ARG H C   1 
ATOM 3081 O O   . ARG D 3 58  ? 246.149 314.730 417.634 1.00 141.13 ? 80  ARG H O   1 
ATOM 3082 C CB  . ARG D 3 58  ? 244.828 314.544 415.210 1.00 141.13 ? 80  ARG H CB  1 
ATOM 3083 C CG  . ARG D 3 58  ? 244.186 314.332 413.850 1.00 141.13 ? 80  ARG H CG  1 
ATOM 3084 C CD  . ARG D 3 58  ? 243.130 315.389 413.578 1.00 141.13 ? 80  ARG H CD  1 
ATOM 3085 N NE  . ARG D 3 58  ? 243.675 316.739 413.665 1.00 141.13 ? 80  ARG H NE  1 
ATOM 3086 C CZ  . ARG D 3 58  ? 244.237 317.386 412.654 1.00 141.13 ? 80  ARG H CZ  1 
ATOM 3087 N NH1 . ARG D 3 58  ? 244.344 316.836 411.455 1.00 141.13 ? 80  ARG H NH1 1 
ATOM 3088 N NH2 . ARG D 3 58  ? 244.703 318.616 412.850 1.00 141.13 ? 80  ARG H NH2 1 
ATOM 3089 N N   . SER D 3 59  ? 246.719 312.554 417.742 1.00 145.21 ? 81  SER H N   1 
ATOM 3090 C CA  . SER D 3 59  ? 247.336 312.683 419.055 1.00 145.21 ? 81  SER H CA  1 
ATOM 3091 C C   . SER D 3 59  ? 248.341 311.558 419.253 1.00 145.21 ? 81  SER H C   1 
ATOM 3092 O O   . SER D 3 59  ? 248.337 310.561 418.528 1.00 145.21 ? 81  SER H O   1 
ATOM 3093 C CB  . SER D 3 59  ? 246.284 312.668 420.168 1.00 145.21 ? 81  SER H CB  1 
ATOM 3094 O OG  . SER D 3 59  ? 245.592 311.433 420.190 1.00 145.21 ? 81  SER H OG  1 
ATOM 3095 N N   . ALA D 3 60  ? 249.209 311.740 420.248 1.00 145.06 ? 82  ALA H N   1 
ATOM 3096 C CA  . ALA D 3 60  ? 250.203 310.747 420.626 1.00 145.06 ? 82  ALA H CA  1 
ATOM 3097 C C   . ALA D 3 60  ? 250.146 310.524 422.130 1.00 145.06 ? 82  ALA H C   1 
ATOM 3098 O O   . ALA D 3 60  ? 249.776 311.422 422.892 1.00 145.06 ? 82  ALA H O   1 
ATOM 3099 C CB  . ALA D 3 60  ? 251.616 311.174 420.211 1.00 145.06 ? 82  ALA H CB  1 
ATOM 3100 N N   . TYR D 3 61  ? 250.521 309.320 422.556 1.00 148.09 ? 83  TYR H N   1 
ATOM 3101 C CA  . TYR D 3 61  ? 250.362 308.910 423.944 1.00 148.09 ? 83  TYR H CA  1 
ATOM 3102 C C   . TYR D 3 61  ? 251.646 308.298 424.485 1.00 148.09 ? 83  TYR H C   1 
ATOM 3103 O O   . TYR D 3 61  ? 252.411 307.673 423.744 1.00 148.09 ? 83  TYR H O   1 
ATOM 3104 C CB  . TYR D 3 61  ? 249.225 307.900 424.096 1.00 148.09 ? 83  TYR H CB  1 
ATOM 3105 C CG  . TYR D 3 61  ? 247.959 308.280 423.371 1.00 148.09 ? 83  TYR H CG  1 
ATOM 3106 C CD1 . TYR D 3 61  ? 247.430 307.457 422.387 1.00 148.09 ? 83  TYR H CD1 1 
ATOM 3107 C CD2 . TYR D 3 61  ? 247.287 309.454 423.675 1.00 148.09 ? 83  TYR H CD2 1 
ATOM 3108 C CE1 . TYR D 3 61  ? 246.271 307.794 421.723 1.00 148.09 ? 83  TYR H CE1 1 
ATOM 3109 C CE2 . TYR D 3 61  ? 246.126 309.800 423.016 1.00 148.09 ? 83  TYR H CE2 1 
ATOM 3110 C CZ  . TYR D 3 61  ? 245.623 308.966 422.042 1.00 148.09 ? 83  TYR H CZ  1 
ATOM 3111 O OH  . TYR D 3 61  ? 244.467 309.310 421.384 1.00 148.09 ? 83  TYR H OH  1 
ATOM 3112 N N   . MET D 3 62  ? 251.873 308.487 425.783 1.00 159.11 ? 84  MET H N   1 
ATOM 3113 C CA  . MET D 3 62  ? 252.903 307.778 426.528 1.00 159.11 ? 84  MET H CA  1 
ATOM 3114 C C   . MET D 3 62  ? 252.238 307.104 427.720 1.00 159.11 ? 84  MET H C   1 
ATOM 3115 O O   . MET D 3 62  ? 251.425 307.725 428.411 1.00 159.11 ? 84  MET H O   1 
ATOM 3116 C CB  . MET D 3 62  ? 254.023 308.721 426.990 1.00 159.11 ? 84  MET H CB  1 
ATOM 3117 C CG  . MET D 3 62  ? 253.601 309.793 427.987 1.00 159.11 ? 84  MET H CG  1 
ATOM 3118 S SD  . MET D 3 62  ? 254.934 310.929 428.418 1.00 159.11 ? 84  MET H SD  1 
ATOM 3119 C CE  . MET D 3 62  ? 255.060 311.905 426.925 1.00 159.11 ? 84  MET H CE  1 
ATOM 3120 N N   . GLN D 3 63  ? 252.545 305.824 427.936 1.00 165.16 ? 85  GLN H N   1 
ATOM 3121 C CA  . GLN D 3 63  ? 251.947 305.121 429.065 1.00 165.16 ? 85  GLN H CA  1 
ATOM 3122 C C   . GLN D 3 63  ? 252.754 305.297 430.346 1.00 165.16 ? 85  GLN H C   1 
ATOM 3123 O O   . GLN D 3 63  ? 252.191 305.195 431.442 1.00 165.16 ? 85  GLN H O   1 
ATOM 3124 C CB  . GLN D 3 63  ? 251.771 303.637 428.734 1.00 165.16 ? 85  GLN H CB  1 
ATOM 3125 C CG  . GLN D 3 63  ? 253.057 302.841 428.626 1.00 165.16 ? 85  GLN H CG  1 
ATOM 3126 C CD  . GLN D 3 63  ? 253.691 302.936 427.251 1.00 165.16 ? 85  GLN H CD  1 
ATOM 3127 O OE1 . GLN D 3 63  ? 253.365 303.819 426.458 1.00 165.16 ? 85  GLN H OE1 1 
ATOM 3128 N NE2 . GLN D 3 63  ? 254.587 302.007 426.954 1.00 165.16 ? 85  GLN H NE2 1 
ATOM 3129 N N   . LEU D 3 64  ? 254.058 305.561 430.229 1.00 169.64 ? 86  LEU H N   1 
ATOM 3130 C CA  . LEU D 3 64  ? 254.907 305.964 431.352 1.00 169.64 ? 86  LEU H CA  1 
ATOM 3131 C C   . LEU D 3 64  ? 254.889 304.909 432.466 1.00 169.64 ? 86  LEU H C   1 
ATOM 3132 O O   . LEU D 3 64  ? 254.399 305.126 433.577 1.00 169.64 ? 86  LEU H O   1 
ATOM 3133 C CB  . LEU D 3 64  ? 254.483 307.346 431.870 1.00 169.64 ? 86  LEU H CB  1 
ATOM 3134 C CG  . LEU D 3 64  ? 255.275 308.004 433.002 1.00 169.64 ? 86  LEU H CG  1 
ATOM 3135 C CD1 . LEU D 3 64  ? 256.709 308.266 432.568 1.00 169.64 ? 86  LEU H CD1 1 
ATOM 3136 C CD2 . LEU D 3 64  ? 254.596 309.291 433.443 1.00 169.64 ? 86  LEU H CD2 1 
ATOM 3137 N N   . ASN D 3 65  ? 255.416 303.736 432.122 1.00 171.90 ? 87  ASN H N   1 
ATOM 3138 C CA  . ASN D 3 65  ? 255.617 302.679 433.102 1.00 171.90 ? 87  ASN H CA  1 
ATOM 3139 C C   . ASN D 3 65  ? 256.766 303.040 434.046 1.00 171.90 ? 87  ASN H C   1 
ATOM 3140 O O   . ASN D 3 65  ? 257.488 304.020 433.839 1.00 171.90 ? 87  ASN H O   1 
ATOM 3141 C CB  . ASN D 3 65  ? 255.808 301.334 432.389 1.00 171.90 ? 87  ASN H CB  1 
ATOM 3142 C CG  . ASN D 3 65  ? 257.227 301.112 431.839 1.00 171.90 ? 87  ASN H CG  1 
ATOM 3143 O OD1 . ASN D 3 65  ? 258.170 301.850 432.122 1.00 171.90 ? 87  ASN H OD1 1 
ATOM 3144 N ND2 . ASN D 3 65  ? 257.367 300.065 431.035 1.00 171.90 ? 87  ASN H ND2 1 
ATOM 3145 N N   . SER D 3 66  ? 256.938 302.238 435.100 1.00 175.49 ? 88  SER H N   1 
ATOM 3146 C CA  . SER D 3 66  ? 257.972 302.458 436.113 1.00 175.49 ? 88  SER H CA  1 
ATOM 3147 C C   . SER D 3 66  ? 257.813 303.844 436.749 1.00 175.49 ? 88  SER H C   1 
ATOM 3148 O O   . SER D 3 66  ? 258.633 304.748 436.582 1.00 175.49 ? 88  SER H O   1 
ATOM 3149 C CB  . SER D 3 66  ? 259.375 302.269 435.524 1.00 175.49 ? 88  SER H CB  1 
ATOM 3150 O OG  . SER D 3 66  ? 259.573 300.931 435.103 1.00 175.49 ? 88  SER H OG  1 
ATOM 3151 N N   . LEU D 3 67  ? 256.717 303.975 437.496 1.00 179.80 ? 89  LEU H N   1 
ATOM 3152 C CA  . LEU D 3 67  ? 256.214 305.256 437.978 1.00 179.80 ? 89  LEU H CA  1 
ATOM 3153 C C   . LEU D 3 67  ? 257.029 305.838 439.131 1.00 179.80 ? 89  LEU H C   1 
ATOM 3154 O O   . LEU D 3 67  ? 256.537 306.740 439.820 1.00 179.80 ? 89  LEU H O   1 
ATOM 3155 C CB  . LEU D 3 67  ? 254.746 305.122 438.400 1.00 179.80 ? 89  LEU H CB  1 
ATOM 3156 C CG  . LEU D 3 67  ? 254.393 304.374 439.692 1.00 179.80 ? 89  LEU H CG  1 
ATOM 3157 C CD1 . LEU D 3 67  ? 252.962 304.686 440.101 1.00 179.80 ? 89  LEU H CD1 1 
ATOM 3158 C CD2 . LEU D 3 67  ? 254.581 302.869 439.552 1.00 179.80 ? 89  LEU H CD2 1 
ATOM 3159 N N   . THR D 3 68  ? 258.251 305.363 439.361 1.00 184.63 ? 90  THR H N   1 
ATOM 3160 C CA  . THR D 3 68  ? 259.090 305.929 440.407 1.00 184.63 ? 90  THR H CA  1 
ATOM 3161 C C   . THR D 3 68  ? 259.520 307.354 440.034 1.00 184.63 ? 90  THR H C   1 
ATOM 3162 O O   . THR D 3 68  ? 259.161 307.893 438.984 1.00 184.63 ? 90  THR H O   1 
ATOM 3163 C CB  . THR D 3 68  ? 260.276 305.007 440.688 1.00 184.63 ? 90  THR H CB  1 
ATOM 3164 O OG1 . THR D 3 68  ? 261.006 305.487 441.825 1.00 184.63 ? 90  THR H OG1 1 
ATOM 3165 C CG2 . THR D 3 68  ? 261.180 304.889 439.486 1.00 184.63 ? 90  THR H CG2 1 
ATOM 3166 N N   . SER D 3 69  ? 260.323 307.964 440.909 1.00 188.04 ? 91  SER H N   1 
ATOM 3167 C CA  . SER D 3 69  ? 260.289 309.409 441.121 1.00 188.04 ? 91  SER H CA  1 
ATOM 3168 C C   . SER D 3 69  ? 261.045 310.248 440.092 1.00 188.04 ? 91  SER H C   1 
ATOM 3169 O O   . SER D 3 69  ? 260.963 311.478 440.167 1.00 188.04 ? 91  SER H O   1 
ATOM 3170 C CB  . SER D 3 69  ? 260.834 309.736 442.513 1.00 188.04 ? 91  SER H CB  1 
ATOM 3171 O OG  . SER D 3 69  ? 260.876 311.136 442.727 1.00 188.04 ? 91  SER H OG  1 
ATOM 3172 N N   . GLU D 3 70  ? 261.770 309.659 439.140 1.00 185.15 ? 92  GLU H N   1 
ATOM 3173 C CA  . GLU D 3 70  ? 262.565 310.473 438.224 1.00 185.15 ? 92  GLU H CA  1 
ATOM 3174 C C   . GLU D 3 70  ? 261.746 311.024 437.057 1.00 185.15 ? 92  GLU H C   1 
ATOM 3175 O O   . GLU D 3 70  ? 262.325 311.425 436.041 1.00 185.15 ? 92  GLU H O   1 
ATOM 3176 C CB  . GLU D 3 70  ? 263.773 309.695 437.685 1.00 185.15 ? 92  GLU H CB  1 
ATOM 3177 C CG  . GLU D 3 70  ? 263.476 308.441 436.870 1.00 185.15 ? 92  GLU H CG  1 
ATOM 3178 C CD  . GLU D 3 70  ? 262.804 307.351 437.664 1.00 185.15 ? 92  GLU H CD  1 
ATOM 3179 O OE1 . GLU D 3 70  ? 262.180 306.468 437.040 1.00 185.15 ? 92  GLU H OE1 1 
ATOM 3180 O OE2 . GLU D 3 70  ? 262.908 307.375 438.908 1.00 185.15 ? 92  GLU H OE2 1 
ATOM 3181 N N   . ASP D 3 71  ? 260.423 311.059 437.183 1.00 186.25 ? 93  ASP H N   1 
ATOM 3182 C CA  . ASP D 3 71  ? 259.527 311.616 436.175 1.00 186.25 ? 93  ASP H CA  1 
ATOM 3183 C C   . ASP D 3 71  ? 258.719 312.767 436.763 1.00 186.25 ? 93  ASP H C   1 
ATOM 3184 O O   . ASP D 3 71  ? 257.498 312.842 436.608 1.00 186.25 ? 93  ASP H O   1 
ATOM 3185 C CB  . ASP D 3 71  ? 258.606 310.535 435.613 1.00 186.25 ? 93  ASP H CB  1 
ATOM 3186 C CG  . ASP D 3 71  ? 257.862 309.777 436.697 1.00 186.25 ? 93  ASP H CG  1 
ATOM 3187 O OD1 . ASP D 3 71  ? 258.034 310.111 437.888 1.00 186.25 ? 93  ASP H OD1 1 
ATOM 3188 O OD2 . ASP D 3 71  ? 257.108 308.841 436.357 1.00 186.25 ? 93  ASP H OD2 1 
ATOM 3189 N N   . SER D 3 72  ? 259.404 313.686 437.444 1.00 184.85 ? 94  SER H N   1 
ATOM 3190 C CA  . SER D 3 72  ? 258.726 314.583 438.373 1.00 184.85 ? 94  SER H CA  1 
ATOM 3191 C C   . SER D 3 72  ? 258.095 315.788 437.681 1.00 184.85 ? 94  SER H C   1 
ATOM 3192 O O   . SER D 3 72  ? 256.867 315.919 437.643 1.00 184.85 ? 94  SER H O   1 
ATOM 3193 C CB  . SER D 3 72  ? 259.712 315.047 439.449 1.00 184.85 ? 94  SER H CB  1 
ATOM 3194 O OG  . SER D 3 72  ? 260.751 315.826 438.883 1.00 184.85 ? 94  SER H OG  1 
ATOM 3195 N N   . ALA D 3 73  ? 258.918 316.678 437.124 1.00 182.52 ? 95  ALA H N   1 
ATOM 3196 C CA  . ALA D 3 73  ? 258.473 318.062 436.948 1.00 182.52 ? 95  ALA H CA  1 
ATOM 3197 C C   . ALA D 3 73  ? 257.600 318.265 435.712 1.00 182.52 ? 95  ALA H C   1 
ATOM 3198 O O   . ALA D 3 73  ? 256.401 318.534 435.827 1.00 182.52 ? 95  ALA H O   1 
ATOM 3199 C CB  . ALA D 3 73  ? 259.693 318.989 436.902 1.00 182.52 ? 95  ALA H CB  1 
ATOM 3200 N N   . VAL D 3 74  ? 258.175 318.112 434.518 1.00 171.32 ? 96  VAL H N   1 
ATOM 3201 C CA  . VAL D 3 74  ? 257.503 318.517 433.286 1.00 171.32 ? 96  VAL H CA  1 
ATOM 3202 C C   . VAL D 3 74  ? 257.998 317.662 432.130 1.00 171.32 ? 96  VAL H C   1 
ATOM 3203 O O   . VAL D 3 74  ? 259.160 317.248 432.088 1.00 171.32 ? 96  VAL H O   1 
ATOM 3204 C CB  . VAL D 3 74  ? 257.718 320.017 432.952 1.00 171.32 ? 96  VAL H CB  1 
ATOM 3205 C CG1 . VAL D 3 74  ? 257.053 320.934 433.972 1.00 171.32 ? 96  VAL H CG1 1 
ATOM 3206 C CG2 . VAL D 3 74  ? 259.203 320.330 432.850 1.00 171.32 ? 96  VAL H CG2 1 
ATOM 3207 N N   . TYR D 3 75  ? 257.095 317.395 431.189 1.00 167.16 ? 97  TYR H N   1 
ATOM 3208 C CA  . TYR D 3 75  ? 257.437 316.873 429.873 1.00 167.16 ? 97  TYR H CA  1 
ATOM 3209 C C   . TYR D 3 75  ? 256.783 317.759 428.825 1.00 167.16 ? 97  TYR H C   1 
ATOM 3210 O O   . TYR D 3 75  ? 255.586 318.051 428.916 1.00 167.16 ? 97  TYR H O   1 
ATOM 3211 C CB  . TYR D 3 75  ? 256.999 315.413 429.688 1.00 167.16 ? 97  TYR H CB  1 
ATOM 3212 C CG  . TYR D 3 75  ? 257.728 314.407 430.555 1.00 167.16 ? 97  TYR H CG  1 
ATOM 3213 C CD1 . TYR D 3 75  ? 257.683 314.475 431.942 1.00 167.16 ? 97  TYR H CD1 1 
ATOM 3214 C CD2 . TYR D 3 75  ? 258.479 313.393 429.976 1.00 167.16 ? 97  TYR H CD2 1 
ATOM 3215 C CE1 . TYR D 3 75  ? 258.359 313.558 432.724 1.00 167.16 ? 97  TYR H CE1 1 
ATOM 3216 C CE2 . TYR D 3 75  ? 259.155 312.474 430.748 1.00 167.16 ? 97  TYR H CE2 1 
ATOM 3217 C CZ  . TYR D 3 75  ? 259.093 312.560 432.121 1.00 167.16 ? 97  TYR H CZ  1 
ATOM 3218 O OH  . TYR D 3 75  ? 259.769 311.642 432.888 1.00 167.16 ? 97  TYR H OH  1 
ATOM 3219 N N   . PHE D 3 76  ? 257.564 318.181 427.837 1.00 159.02 ? 98  PHE H N   1 
ATOM 3220 C CA  . PHE D 3 76  ? 257.104 319.115 426.821 1.00 159.02 ? 98  PHE H CA  1 
ATOM 3221 C C   . PHE D 3 76  ? 256.740 318.384 425.536 1.00 159.02 ? 98  PHE H C   1 
ATOM 3222 O O   . PHE D 3 76  ? 257.481 317.526 425.052 1.00 159.02 ? 98  PHE H O   1 
ATOM 3223 C CB  . PHE D 3 76  ? 258.168 320.174 426.526 1.00 159.02 ? 98  PHE H CB  1 
ATOM 3224 C CG  . PHE D 3 76  ? 258.416 321.124 427.664 1.00 159.02 ? 98  PHE H CG  1 
ATOM 3225 C CD1 . PHE D 3 76  ? 259.484 322.006 427.624 1.00 159.02 ? 98  PHE H CD1 1 
ATOM 3226 C CD2 . PHE D 3 76  ? 257.574 321.151 428.764 1.00 159.02 ? 98  PHE H CD2 1 
ATOM 3227 C CE1 . PHE D 3 76  ? 259.715 322.885 428.664 1.00 159.02 ? 98  PHE H CE1 1 
ATOM 3228 C CE2 . PHE D 3 76  ? 257.801 322.028 429.807 1.00 159.02 ? 98  PHE H CE2 1 
ATOM 3229 C CZ  . PHE D 3 76  ? 258.872 322.897 429.756 1.00 159.02 ? 98  PHE H CZ  1 
ATOM 3230 N N   . CYS D 3 77  ? 255.582 318.741 424.987 1.00 153.02 ? 99  CYS H N   1 
ATOM 3231 C CA  . CYS D 3 77  ? 255.118 318.202 423.716 1.00 153.02 ? 99  CYS H CA  1 
ATOM 3232 C C   . CYS D 3 77  ? 255.623 319.096 422.589 1.00 153.02 ? 99  CYS H C   1 
ATOM 3233 O O   . CYS D 3 77  ? 255.159 320.231 422.436 1.00 153.02 ? 99  CYS H O   1 
ATOM 3234 C CB  . CYS D 3 77  ? 253.593 318.113 423.699 1.00 153.02 ? 99  CYS H CB  1 
ATOM 3235 S SG  . CYS D 3 77  ? 252.892 317.450 422.177 1.00 153.02 ? 99  CYS H SG  1 
ATOM 3236 N N   . ALA D 3 78  ? 256.568 318.584 421.803 1.00 143.32 ? 100 ALA H N   1 
ATOM 3237 C CA  . ALA D 3 78  ? 257.220 319.362 420.761 1.00 143.32 ? 100 ALA H CA  1 
ATOM 3238 C C   . ALA D 3 78  ? 256.943 318.744 419.400 1.00 143.32 ? 100 ALA H C   1 
ATOM 3239 O O   . ALA D 3 78  ? 256.868 317.521 419.258 1.00 143.32 ? 100 ALA H O   1 
ATOM 3240 C CB  . ALA D 3 78  ? 258.732 319.451 420.993 1.00 143.32 ? 100 ALA H CB  1 
ATOM 3241 N N   . ARG D 3 79  ? 256.815 319.604 418.396 1.00 132.46 ? 101 ARG H N   1 
ATOM 3242 C CA  . ARG D 3 79  ? 256.426 319.202 417.053 1.00 132.46 ? 101 ARG H CA  1 
ATOM 3243 C C   . ARG D 3 79  ? 257.609 319.312 416.103 1.00 132.46 ? 101 ARG H C   1 
ATOM 3244 O O   . ARG D 3 79  ? 258.290 320.339 416.064 1.00 132.46 ? 101 ARG H O   1 
ATOM 3245 C CB  . ARG D 3 79  ? 255.271 320.064 416.539 1.00 132.46 ? 101 ARG H CB  1 
ATOM 3246 C CG  . ARG D 3 79  ? 254.806 319.700 415.146 1.00 132.46 ? 101 ARG H CG  1 
ATOM 3247 C CD  . ARG D 3 79  ? 255.319 320.678 414.103 1.00 132.46 ? 101 ARG H CD  1 
ATOM 3248 N NE  . ARG D 3 79  ? 254.828 320.348 412.772 1.00 132.46 ? 101 ARG H NE  1 
ATOM 3249 C CZ  . ARG D 3 79  ? 255.331 320.834 411.647 1.00 132.46 ? 101 ARG H CZ  1 
ATOM 3250 N NH1 . ARG D 3 79  ? 256.340 321.689 411.654 1.00 132.46 ? 101 ARG H NH1 1 
ATOM 3251 N NH2 . ARG D 3 79  ? 254.810 320.451 410.485 1.00 132.46 ? 101 ARG H NH2 1 
ATOM 3252 N N   . SER D 3 80  ? 257.835 318.257 415.326 1.00 130.91 ? 102 SER H N   1 
ATOM 3253 C CA  . SER D 3 80  ? 258.891 318.225 414.325 1.00 130.91 ? 102 SER H CA  1 
ATOM 3254 C C   . SER D 3 80  ? 258.281 317.958 412.959 1.00 130.91 ? 102 SER H C   1 
ATOM 3255 O O   . SER D 3 80  ? 257.368 317.139 412.828 1.00 130.91 ? 102 SER H O   1 
ATOM 3256 C CB  . SER D 3 80  ? 259.934 317.155 414.647 1.00 130.91 ? 102 SER H CB  1 
ATOM 3257 O OG  . SER D 3 80  ? 260.940 317.106 413.653 1.00 130.91 ? 102 SER H OG  1 
ATOM 3258 N N   . GLY D 3 81  ? 258.792 318.649 411.943 1.00 120.20 ? 103 GLY H N   1 
ATOM 3259 C CA  . GLY D 3 81  ? 258.217 318.544 410.618 1.00 120.20 ? 103 GLY H CA  1 
ATOM 3260 C C   . GLY D 3 81  ? 259.138 317.993 409.550 1.00 120.20 ? 103 GLY H C   1 
ATOM 3261 O O   . GLY D 3 81  ? 260.195 318.566 409.271 1.00 120.20 ? 103 GLY H O   1 
ATOM 3262 N N   . TYR D 3 82  ? 258.734 316.874 408.947 1.00 113.25 ? 104 TYR H N   1 
ATOM 3263 C CA  . TYR D 3 82  ? 259.367 316.312 407.753 1.00 113.25 ? 104 TYR H CA  1 
ATOM 3264 C C   . TYR D 3 82  ? 260.852 316.012 407.992 1.00 113.25 ? 104 TYR H C   1 
ATOM 3265 O O   . TYR D 3 82  ? 261.752 316.637 407.429 1.00 113.25 ? 104 TYR H O   1 
ATOM 3266 C CB  . TYR D 3 82  ? 259.166 317.238 406.547 1.00 113.25 ? 104 TYR H CB  1 
ATOM 3267 C CG  . TYR D 3 82  ? 259.899 316.783 405.309 1.00 113.25 ? 104 TYR H CG  1 
ATOM 3268 C CD1 . TYR D 3 82  ? 259.637 315.548 404.741 1.00 113.25 ? 104 TYR H CD1 1 
ATOM 3269 C CD2 . TYR D 3 82  ? 260.860 317.587 404.715 1.00 113.25 ? 104 TYR H CD2 1 
ATOM 3270 C CE1 . TYR D 3 82  ? 260.309 315.128 403.617 1.00 113.25 ? 104 TYR H CE1 1 
ATOM 3271 C CE2 . TYR D 3 82  ? 261.536 317.175 403.593 1.00 113.25 ? 104 TYR H CE2 1 
ATOM 3272 C CZ  . TYR D 3 82  ? 261.256 315.946 403.049 1.00 113.25 ? 104 TYR H CZ  1 
ATOM 3273 O OH  . TYR D 3 82  ? 261.929 315.532 401.927 1.00 113.25 ? 104 TYR H OH  1 
ATOM 3274 N N   . TYR D 3 83  ? 261.080 315.048 408.884 1.00 116.27 ? 105 TYR H N   1 
ATOM 3275 C CA  . TYR D 3 83  ? 262.378 314.391 409.000 1.00 116.27 ? 105 TYR H CA  1 
ATOM 3276 C C   . TYR D 3 83  ? 263.554 315.337 409.224 1.00 116.27 ? 105 TYR H C   1 
ATOM 3277 O O   . TYR D 3 83  ? 264.008 315.529 410.356 1.00 116.27 ? 105 TYR H O   1 
ATOM 3278 C CB  . TYR D 3 83  ? 262.665 313.562 407.745 1.00 116.27 ? 105 TYR H CB  1 
ATOM 3279 C CG  . TYR D 3 83  ? 261.910 312.260 407.639 1.00 116.27 ? 105 TYR H CG  1 
ATOM 3280 C CD1 . TYR D 3 83  ? 261.193 311.756 408.713 1.00 116.27 ? 105 TYR H CD1 1 
ATOM 3281 C CD2 . TYR D 3 83  ? 261.944 311.516 406.468 1.00 116.27 ? 105 TYR H CD2 1 
ATOM 3282 C CE1 . TYR D 3 83  ? 260.515 310.558 408.616 1.00 116.27 ? 105 TYR H CE1 1 
ATOM 3283 C CE2 . TYR D 3 83  ? 261.271 310.318 406.363 1.00 116.27 ? 105 TYR H CE2 1 
ATOM 3284 C CZ  . TYR D 3 83  ? 260.557 309.844 407.438 1.00 116.27 ? 105 TYR H CZ  1 
ATOM 3285 O OH  . TYR D 3 83  ? 259.884 308.649 407.332 1.00 116.27 ? 105 TYR H OH  1 
ATOM 3286 N N   . PHE D 3 84  ? 264.048 315.926 408.136 1.00 108.72 ? 106 PHE H N   1 
ATOM 3287 C CA  . PHE D 3 84  ? 265.416 316.427 408.051 1.00 108.72 ? 106 PHE H CA  1 
ATOM 3288 C C   . PHE D 3 84  ? 265.587 317.836 408.613 1.00 108.72 ? 106 PHE H C   1 
ATOM 3289 O O   . PHE D 3 84  ? 266.352 318.033 409.562 1.00 108.72 ? 106 PHE H O   1 
ATOM 3290 C CB  . PHE D 3 84  ? 265.876 316.376 406.591 1.00 108.72 ? 106 PHE H CB  1 
ATOM 3291 C CG  . PHE D 3 84  ? 265.719 315.019 405.955 1.00 108.72 ? 106 PHE H CG  1 
ATOM 3292 C CD1 . PHE D 3 84  ? 265.896 313.863 406.697 1.00 108.72 ? 106 PHE H CD1 1 
ATOM 3293 C CD2 . PHE D 3 84  ? 265.364 314.901 404.621 1.00 108.72 ? 106 PHE H CD2 1 
ATOM 3294 C CE1 . PHE D 3 84  ? 265.739 312.617 406.116 1.00 108.72 ? 106 PHE H CE1 1 
ATOM 3295 C CE2 . PHE D 3 84  ? 265.207 313.655 404.036 1.00 108.72 ? 106 PHE H CE2 1 
ATOM 3296 C CZ  . PHE D 3 84  ? 265.394 312.514 404.785 1.00 108.72 ? 106 PHE H CZ  1 
ATOM 3297 N N   . SER D 3 85  ? 264.895 318.825 408.049 1.00 120.05 ? 107 SER H N   1 
ATOM 3298 C CA  . SER D 3 85  ? 265.143 320.220 408.391 1.00 120.05 ? 107 SER H CA  1 
ATOM 3299 C C   . SER D 3 85  ? 263.831 320.937 408.677 1.00 120.05 ? 107 SER H C   1 
ATOM 3300 O O   . SER D 3 85  ? 262.742 320.422 408.410 1.00 120.05 ? 107 SER H O   1 
ATOM 3301 C CB  . SER D 3 85  ? 265.902 320.943 407.273 1.00 120.05 ? 107 SER H CB  1 
ATOM 3302 O OG  . SER D 3 85  ? 265.991 322.332 407.538 1.00 120.05 ? 107 SER H OG  1 
ATOM 3303 N N   . SER D 3 86  ? 263.956 322.148 409.225 1.00 130.95 ? 108 SER H N   1 
ATOM 3304 C CA  . SER D 3 86  ? 262.823 323.027 409.516 1.00 130.95 ? 108 SER H CA  1 
ATOM 3305 C C   . SER D 3 86  ? 261.829 322.356 410.465 1.00 130.95 ? 108 SER H C   1 
ATOM 3306 O O   . SER D 3 86  ? 260.684 322.068 410.113 1.00 130.95 ? 108 SER H O   1 
ATOM 3307 C CB  . SER D 3 86  ? 262.135 323.477 408.222 1.00 130.95 ? 108 SER H CB  1 
ATOM 3308 O OG  . SER D 3 86  ? 261.361 322.429 407.668 1.00 130.95 ? 108 SER H OG  1 
ATOM 3309 N N   . ASN D 3 87  ? 262.292 322.106 411.690 1.00 137.53 ? 109 ASN H N   1 
ATOM 3310 C CA  . ASN D 3 87  ? 261.472 321.409 412.675 1.00 137.53 ? 109 ASN H CA  1 
ATOM 3311 C C   . ASN D 3 87  ? 261.490 322.092 414.038 1.00 137.53 ? 109 ASN H C   1 
ATOM 3312 O O   . ASN D 3 87  ? 261.948 323.232 414.168 1.00 137.53 ? 109 ASN H O   1 
ATOM 3313 C CB  . ASN D 3 87  ? 261.929 319.956 412.814 1.00 137.53 ? 109 ASN H CB  1 
ATOM 3314 C CG  . ASN D 3 87  ? 263.390 319.834 413.198 1.00 137.53 ? 109 ASN H CG  1 
ATOM 3315 O OD1 . ASN D 3 87  ? 264.072 320.831 413.432 1.00 137.53 ? 109 ASN H OD1 1 
ATOM 3316 N ND2 . ASN D 3 87  ? 263.878 318.601 413.268 1.00 137.53 ? 109 ASN H ND2 1 
ATOM 3317 N N   . TYR D 3 88  ? 260.967 321.392 415.050 1.00 142.05 ? 110 TYR H N   1 
ATOM 3318 C CA  . TYR D 3 88  ? 260.950 321.845 416.444 1.00 142.05 ? 110 TYR H CA  1 
ATOM 3319 C C   . TYR D 3 88  ? 260.074 323.086 416.628 1.00 142.05 ? 110 TYR H C   1 
ATOM 3320 O O   . TYR D 3 88  ? 260.455 324.046 417.296 1.00 142.05 ? 110 TYR H O   1 
ATOM 3321 C CB  . TYR D 3 88  ? 262.368 322.088 416.965 1.00 142.05 ? 110 TYR H CB  1 
ATOM 3322 C CG  . TYR D 3 88  ? 262.998 320.849 417.548 1.00 142.05 ? 110 TYR H CG  1 
ATOM 3323 C CD1 . TYR D 3 88  ? 263.434 319.820 416.726 1.00 142.05 ? 110 TYR H CD1 1 
ATOM 3324 C CD2 . TYR D 3 88  ? 263.144 320.700 418.919 1.00 142.05 ? 110 TYR H CD2 1 
ATOM 3325 C CE1 . TYR D 3 88  ? 264.005 318.682 417.253 1.00 142.05 ? 110 TYR H CE1 1 
ATOM 3326 C CE2 . TYR D 3 88  ? 263.714 319.566 419.456 1.00 142.05 ? 110 TYR H CE2 1 
ATOM 3327 C CZ  . TYR D 3 88  ? 264.143 318.560 418.618 1.00 142.05 ? 110 TYR H CZ  1 
ATOM 3328 O OH  . TYR D 3 88  ? 264.712 317.426 419.148 1.00 142.05 ? 110 TYR H OH  1 
ATOM 3329 N N   . ASP D 3 89  ? 258.870 323.038 416.057 1.00 141.53 ? 111 ASP H N   1 
ATOM 3330 C CA  . ASP D 3 89  ? 257.893 324.117 416.191 1.00 141.53 ? 111 ASP H CA  1 
ATOM 3331 C C   . ASP D 3 89  ? 257.040 323.833 417.425 1.00 141.53 ? 111 ASP H C   1 
ATOM 3332 O O   . ASP D 3 89  ? 255.959 323.249 417.351 1.00 141.53 ? 111 ASP H O   1 
ATOM 3333 C CB  . ASP D 3 89  ? 257.044 324.233 414.930 1.00 141.53 ? 111 ASP H CB  1 
ATOM 3334 C CG  . ASP D 3 89  ? 257.836 324.731 413.743 1.00 141.53 ? 111 ASP H CG  1 
ATOM 3335 O OD1 . ASP D 3 89  ? 258.810 325.483 413.952 1.00 141.53 ? 111 ASP H OD1 1 
ATOM 3336 O OD2 . ASP D 3 89  ? 257.486 324.370 412.600 1.00 141.53 ? 111 ASP H OD2 1 
ATOM 3337 N N   . PHE D 3 90  ? 257.548 324.259 418.577 1.00 140.99 ? 112 PHE H N   1 
ATOM 3338 C CA  . PHE D 3 90  ? 256.892 323.995 419.855 1.00 140.99 ? 112 PHE H CA  1 
ATOM 3339 C C   . PHE D 3 90  ? 255.500 324.613 419.908 1.00 140.99 ? 112 PHE H C   1 
ATOM 3340 O O   . PHE D 3 90  ? 254.528 323.940 420.249 1.00 140.99 ? 112 PHE H O   1 
ATOM 3341 C CB  . PHE D 3 90  ? 257.737 324.525 421.015 1.00 140.99 ? 112 PHE H CB  1 
ATOM 3342 C CG  . PHE D 3 90  ? 258.889 323.634 421.384 1.00 140.99 ? 112 PHE H CG  1 
ATOM 3343 C CD1 . PHE D 3 90  ? 259.900 323.374 420.475 1.00 140.99 ? 112 PHE H CD1 1 
ATOM 3344 C CD2 . PHE D 3 90  ? 258.952 323.044 422.634 1.00 140.99 ? 112 PHE H CD2 1 
ATOM 3345 C CE1 . PHE D 3 90  ? 260.958 322.554 420.810 1.00 140.99 ? 112 PHE H CE1 1 
ATOM 3346 C CE2 . PHE D 3 90  ? 260.005 322.218 422.972 1.00 140.99 ? 112 PHE H CE2 1 
ATOM 3347 C CZ  . PHE D 3 90  ? 261.011 321.976 422.060 1.00 140.99 ? 112 PHE H CZ  1 
ATOM 3348 N N   . ALA E 1 1   ? 276.524 253.084 396.746 1.00 97.33  ? 1   ALA C N   1 
ATOM 3349 C CA  . ALA E 1 1   ? 276.561 252.010 397.731 1.00 97.33  ? 1   ALA C CA  1 
ATOM 3350 C C   . ALA E 1 1   ? 275.326 251.126 397.611 1.00 97.33  ? 1   ALA C C   1 
ATOM 3351 O O   . ALA E 1 1   ? 275.074 250.529 396.565 1.00 97.33  ? 1   ALA C O   1 
ATOM 3352 C CB  . ALA E 1 1   ? 276.671 252.582 399.136 1.00 97.33  ? 1   ALA C CB  1 
ATOM 3353 N N   . LYS E 1 2   ? 274.560 251.045 398.696 1.00 91.83  ? 2   LYS C N   1 
ATOM 3354 C CA  . LYS E 1 2   ? 273.297 250.320 398.725 1.00 91.83  ? 2   LYS C CA  1 
ATOM 3355 C C   . LYS E 1 2   ? 272.190 251.300 399.079 1.00 91.83  ? 2   LYS C C   1 
ATOM 3356 O O   . LYS E 1 2   ? 272.192 251.872 400.174 1.00 91.83  ? 2   LYS C O   1 
ATOM 3357 C CB  . LYS E 1 2   ? 273.342 249.169 399.733 1.00 91.83  ? 2   LYS C CB  1 
ATOM 3358 C CG  . LYS E 1 2   ? 272.002 248.485 399.950 1.00 91.83  ? 2   LYS C CG  1 
ATOM 3359 C CD  . LYS E 1 2   ? 271.501 247.817 398.682 1.00 91.83  ? 2   LYS C CD  1 
ATOM 3360 C CE  . LYS E 1 2   ? 272.291 246.560 398.370 1.00 91.83  ? 2   LYS C CE  1 
ATOM 3361 N NZ  . LYS E 1 2   ? 271.999 245.474 399.343 1.00 91.83  ? 2   LYS C NZ  1 
ATOM 3362 N N   . LEU E 1 3   ? 271.255 251.496 398.155 1.00 77.33  ? 3   LEU C N   1 
ATOM 3363 C CA  . LEU E 1 3   ? 270.136 252.390 398.412 1.00 77.33  ? 3   LEU C CA  1 
ATOM 3364 C C   . LEU E 1 3   ? 269.259 251.815 399.512 1.00 77.33  ? 3   LEU C C   1 
ATOM 3365 O O   . LEU E 1 3   ? 268.824 250.662 399.436 1.00 77.33  ? 3   LEU C O   1 
ATOM 3366 C CB  . LEU E 1 3   ? 269.316 252.603 397.141 1.00 77.33  ? 3   LEU C CB  1 
ATOM 3367 C CG  . LEU E 1 3   ? 270.078 252.996 395.877 1.00 77.33  ? 3   LEU C CG  1 
ATOM 3368 C CD1 . LEU E 1 3   ? 270.376 251.773 395.026 1.00 77.33  ? 3   LEU C CD1 1 
ATOM 3369 C CD2 . LEU E 1 3   ? 269.290 254.022 395.085 1.00 77.33  ? 3   LEU C CD2 1 
ATOM 3370 N N   . GLU E 1 4   ? 269.000 252.617 400.537 1.00 82.43  ? 4   GLU C N   1 
ATOM 3371 C CA  . GLU E 1 4   ? 268.168 252.211 401.657 1.00 82.43  ? 4   GLU C CA  1 
ATOM 3372 C C   . GLU E 1 4   ? 267.225 253.359 401.990 1.00 82.43  ? 4   GLU C C   1 
ATOM 3373 O O   . GLU E 1 4   ? 267.485 254.518 401.654 1.00 82.43  ? 4   GLU C O   1 
ATOM 3374 C CB  . GLU E 1 4   ? 269.032 251.809 402.862 1.00 82.43  ? 4   GLU C CB  1 
ATOM 3375 C CG  . GLU E 1 4   ? 268.255 251.321 404.075 1.00 82.43  ? 4   GLU C CG  1 
ATOM 3376 C CD  . GLU E 1 4   ? 267.509 250.026 403.808 1.00 82.43  ? 4   GLU C CD  1 
ATOM 3377 O OE1 . GLU E 1 4   ? 267.939 249.259 402.921 1.00 82.43  ? 4   GLU C OE1 1 
ATOM 3378 O OE2 . GLU E 1 4   ? 266.487 249.777 404.481 1.00 82.43  ? 4   GLU C OE2 1 
ATOM 3379 N N   . THR E 1 5   ? 266.108 253.031 402.639 1.00 85.32  ? 5   THR C N   1 
ATOM 3380 C CA  . THR E 1 5   ? 265.128 254.047 402.994 1.00 85.32  ? 5   THR C CA  1 
ATOM 3381 C C   . THR E 1 5   ? 265.773 255.122 403.857 1.00 85.32  ? 5   THR C C   1 
ATOM 3382 O O   . THR E 1 5   ? 266.124 254.879 405.015 1.00 85.32  ? 5   THR C O   1 
ATOM 3383 C CB  . THR E 1 5   ? 263.954 253.416 403.739 1.00 85.32  ? 5   THR C CB  1 
ATOM 3384 O OG1 . THR E 1 5   ? 264.418 252.848 404.969 1.00 85.32  ? 5   THR C OG1 1 
ATOM 3385 C CG2 . THR E 1 5   ? 263.315 252.327 402.897 1.00 85.32  ? 5   THR C CG2 1 
ATOM 3386 N N   . VAL E 1 6   ? 265.923 256.313 403.288 1.00 81.53  ? 6   VAL C N   1 
ATOM 3387 C CA  . VAL E 1 6   ? 266.513 257.454 403.974 1.00 81.53  ? 6   VAL C CA  1 
ATOM 3388 C C   . VAL E 1 6   ? 265.385 258.344 404.471 1.00 81.53  ? 6   VAL C C   1 
ATOM 3389 O O   . VAL E 1 6   ? 264.439 258.637 403.729 1.00 81.53  ? 6   VAL C O   1 
ATOM 3390 C CB  . VAL E 1 6   ? 267.487 258.223 403.063 1.00 81.53  ? 6   VAL C CB  1 
ATOM 3391 C CG1 . VAL E 1 6   ? 266.792 258.704 401.799 1.00 81.53  ? 6   VAL C CG1 1 
ATOM 3392 C CG2 . VAL E 1 6   ? 268.098 259.393 403.814 1.00 81.53  ? 6   VAL C CG2 1 
ATOM 3393 N N   . THR E 1 7   ? 265.468 258.748 405.738 1.00 83.44  ? 7   THR C N   1 
ATOM 3394 C CA  . THR E 1 7   ? 264.429 259.545 406.381 1.00 83.44  ? 7   THR C CA  1 
ATOM 3395 C C   . THR E 1 7   ? 265.048 260.860 406.852 1.00 83.44  ? 7   THR C C   1 
ATOM 3396 O O   . THR E 1 7   ? 265.465 260.995 408.003 1.00 83.44  ? 7   THR C O   1 
ATOM 3397 C CB  . THR E 1 7   ? 263.793 258.786 407.542 1.00 83.44  ? 7   THR C CB  1 
ATOM 3398 O OG1 . THR E 1 7   ? 264.813 258.380 408.460 1.00 83.44  ? 7   THR C OG1 1 
ATOM 3399 C CG2 . THR E 1 7   ? 263.066 257.556 407.031 1.00 83.44  ? 7   THR C CG2 1 
ATOM 3400 N N   . LEU E 1 8   ? 265.101 261.835 405.950 1.00 91.89  ? 8   LEU C N   1 
ATOM 3401 C CA  . LEU E 1 8   ? 265.552 263.165 406.328 1.00 91.89  ? 8   LEU C CA  1 
ATOM 3402 C C   . LEU E 1 8   ? 264.398 263.937 406.953 1.00 91.89  ? 8   LEU C C   1 
ATOM 3403 O O   . LEU E 1 8   ? 263.284 263.951 406.423 1.00 91.89  ? 8   LEU C O   1 
ATOM 3404 C CB  . LEU E 1 8   ? 266.119 263.904 405.114 1.00 91.89  ? 8   LEU C CB  1 
ATOM 3405 C CG  . LEU E 1 8   ? 265.199 264.431 404.012 1.00 91.89  ? 8   LEU C CG  1 
ATOM 3406 C CD1 . LEU E 1 8   ? 265.951 265.424 403.148 1.00 91.89  ? 8   LEU C CD1 1 
ATOM 3407 C CD2 . LEU E 1 8   ? 264.655 263.302 403.158 1.00 91.89  ? 8   LEU C CD2 1 
ATOM 3408 N N   . GLY E 1 9   ? 264.661 264.561 408.097 1.00 102.14 ? 9   GLY C N   1 
ATOM 3409 C CA  . GLY E 1 9   ? 263.599 265.179 408.863 1.00 102.14 ? 9   GLY C CA  1 
ATOM 3410 C C   . GLY E 1 9   ? 263.840 266.624 409.239 1.00 102.14 ? 9   GLY C C   1 
ATOM 3411 O O   . GLY E 1 9   ? 264.912 267.176 408.975 1.00 102.14 ? 9   GLY C O   1 
ATOM 3412 N N   . ASN E 1 10  ? 262.837 267.239 409.861 1.00 102.26 ? 10  ASN C N   1 
ATOM 3413 C CA  . ASN E 1 10  ? 262.891 268.629 410.303 1.00 102.26 ? 10  ASN C CA  1 
ATOM 3414 C C   . ASN E 1 10  ? 263.213 269.558 409.132 1.00 102.26 ? 10  ASN C C   1 
ATOM 3415 O O   . ASN E 1 10  ? 264.179 270.322 409.148 1.00 102.26 ? 10  ASN C O   1 
ATOM 3416 C CB  . ASN E 1 10  ? 263.898 268.799 411.444 1.00 102.26 ? 10  ASN C CB  1 
ATOM 3417 C CG  . ASN E 1 10  ? 263.642 270.048 412.268 1.00 102.26 ? 10  ASN C CG  1 
ATOM 3418 O OD1 . ASN E 1 10  ? 263.602 271.159 411.742 1.00 102.26 ? 10  ASN C OD1 1 
ATOM 3419 N ND2 . ASN E 1 10  ? 263.465 269.867 413.572 1.00 102.26 ? 10  ASN C ND2 1 
ATOM 3420 N N   . ILE E 1 11  ? 262.381 269.467 408.093 1.00 101.44 ? 11  ILE C N   1 
ATOM 3421 C CA  . ILE E 1 11  ? 262.511 270.310 406.914 1.00 101.44 ? 11  ILE C CA  1 
ATOM 3422 C C   . ILE E 1 11  ? 261.165 270.957 406.623 1.00 101.44 ? 11  ILE C C   1 
ATOM 3423 O O   . ILE E 1 11  ? 260.152 270.660 407.259 1.00 101.44 ? 11  ILE C O   1 
ATOM 3424 C CB  . ILE E 1 11  ? 263.006 269.535 405.676 1.00 101.44 ? 11  ILE C CB  1 
ATOM 3425 C CG1 . ILE E 1 11  ? 261.881 268.688 405.091 1.00 101.44 ? 11  ILE C CG1 1 
ATOM 3426 C CG2 . ILE E 1 11  ? 264.191 268.658 406.030 1.00 101.44 ? 11  ILE C CG2 1 
ATOM 3427 C CD1 . ILE E 1 11  ? 262.136 268.272 403.667 1.00 101.44 ? 11  ILE C CD1 1 
ATOM 3428 N N   . GLY E 1 12  ? 261.168 271.844 405.638 1.00 98.41  ? 12  GLY C N   1 
ATOM 3429 C CA  . GLY E 1 12  ? 260.001 272.623 405.281 1.00 98.41  ? 12  GLY C CA  1 
ATOM 3430 C C   . GLY E 1 12  ? 260.123 274.062 405.749 1.00 98.41  ? 12  GLY C C   1 
ATOM 3431 O O   . GLY E 1 12  ? 260.965 274.413 406.574 1.00 98.41  ? 12  GLY C O   1 
ATOM 3432 N N   . LYS E 1 13  ? 259.251 274.901 405.187 1.00 93.04  ? 13  LYS C N   1 
ATOM 3433 C CA  . LYS E 1 13  ? 259.264 276.314 405.550 1.00 93.04  ? 13  LYS C CA  1 
ATOM 3434 C C   . LYS E 1 13  ? 259.016 276.490 407.041 1.00 93.04  ? 13  LYS C C   1 
ATOM 3435 O O   . LYS E 1 13  ? 259.732 277.236 407.718 1.00 93.04  ? 13  LYS C O   1 
ATOM 3436 C CB  . LYS E 1 13  ? 258.226 277.084 404.735 1.00 93.04  ? 13  LYS C CB  1 
ATOM 3437 C CG  . LYS E 1 13  ? 258.214 278.574 405.039 1.00 93.04  ? 13  LYS C CG  1 
ATOM 3438 C CD  . LYS E 1 13  ? 259.523 279.229 404.621 1.00 93.04  ? 13  LYS C CD  1 
ATOM 3439 C CE  . LYS E 1 13  ? 259.521 280.722 404.905 1.00 93.04  ? 13  LYS C CE  1 
ATOM 3440 N NZ  . LYS E 1 13  ? 259.568 281.009 406.365 1.00 93.04  ? 13  LYS C NZ  1 
ATOM 3441 N N   . ASP E 1 14  ? 258.006 275.802 407.572 1.00 100.76 ? 14  ASP C N   1 
ATOM 3442 C CA  . ASP E 1 14  ? 257.833 275.765 409.019 1.00 100.76 ? 14  ASP C CA  1 
ATOM 3443 C C   . ASP E 1 14  ? 258.900 274.895 409.669 1.00 100.76 ? 14  ASP C C   1 
ATOM 3444 O O   . ASP E 1 14  ? 259.310 275.149 410.808 1.00 100.76 ? 14  ASP C O   1 
ATOM 3445 C CB  . ASP E 1 14  ? 256.433 275.261 409.368 1.00 100.76 ? 14  ASP C CB  1 
ATOM 3446 C CG  . ASP E 1 14  ? 255.338 276.189 408.874 1.00 100.76 ? 14  ASP C CG  1 
ATOM 3447 O OD1 . ASP E 1 14  ? 255.068 277.207 409.545 1.00 100.76 ? 14  ASP C OD1 1 
ATOM 3448 O OD2 . ASP E 1 14  ? 254.747 275.899 407.813 1.00 100.76 ? 14  ASP C OD2 1 
ATOM 3449 N N   . GLY E 1 15  ? 259.362 273.866 408.959 1.00 101.85 ? 15  GLY C N   1 
ATOM 3450 C CA  . GLY E 1 15  ? 260.397 272.985 409.450 1.00 101.85 ? 15  GLY C CA  1 
ATOM 3451 C C   . GLY E 1 15  ? 259.910 271.825 410.288 1.00 101.85 ? 15  GLY C C   1 
ATOM 3452 O O   . GLY E 1 15  ? 260.712 270.946 410.623 1.00 101.85 ? 15  GLY C O   1 
ATOM 3453 N N   . LYS E 1 16  ? 258.624 271.790 410.639 1.00 103.34 ? 16  LYS C N   1 
ATOM 3454 C CA  . LYS E 1 16  ? 258.125 270.728 411.505 1.00 103.34 ? 16  LYS C CA  1 
ATOM 3455 C C   . LYS E 1 16  ? 257.935 269.425 410.740 1.00 103.34 ? 16  LYS C C   1 
ATOM 3456 O O   . LYS E 1 16  ? 258.206 268.341 411.270 1.00 103.34 ? 16  LYS C O   1 
ATOM 3457 C CB  . LYS E 1 16  ? 256.814 271.159 412.164 1.00 103.34 ? 16  LYS C CB  1 
ATOM 3458 C CG  . LYS E 1 16  ? 256.977 272.077 413.372 1.00 103.34 ? 16  LYS C CG  1 
ATOM 3459 C CD  . LYS E 1 16  ? 257.392 273.486 412.975 1.00 103.34 ? 16  LYS C CD  1 
ATOM 3460 C CE  . LYS E 1 16  ? 257.455 274.404 414.183 1.00 103.34 ? 16  LYS C CE  1 
ATOM 3461 N NZ  . LYS E 1 16  ? 257.972 275.753 413.825 1.00 103.34 ? 16  LYS C NZ  1 
ATOM 3462 N N   . GLN E 1 17  ? 257.475 269.507 409.495 1.00 104.23 ? 17  GLN C N   1 
ATOM 3463 C CA  . GLN E 1 17  ? 257.109 268.312 408.753 1.00 104.23 ? 17  GLN C CA  1 
ATOM 3464 C C   . GLN E 1 17  ? 258.351 267.538 408.315 1.00 104.23 ? 17  GLN C C   1 
ATOM 3465 O O   . GLN E 1 17  ? 259.480 268.034 408.352 1.00 104.23 ? 17  GLN C O   1 
ATOM 3466 C CB  . GLN E 1 17  ? 256.257 268.675 407.539 1.00 104.23 ? 17  GLN C CB  1 
ATOM 3467 C CG  . GLN E 1 17  ? 256.838 269.782 406.683 1.00 104.23 ? 17  GLN C CG  1 
ATOM 3468 C CD  . GLN E 1 17  ? 255.984 270.079 405.469 1.00 104.23 ? 17  GLN C CD  1 
ATOM 3469 O OE1 . GLN E 1 17  ? 255.427 269.172 404.852 1.00 104.23 ? 17  GLN C OE1 1 
ATOM 3470 N NE2 . GLN E 1 17  ? 255.872 271.355 405.121 1.00 104.23 ? 17  GLN C NE2 1 
ATOM 3471 N N   . THR E 1 18  ? 258.120 266.296 407.894 1.00 99.24  ? 18  THR C N   1 
ATOM 3472 C CA  . THR E 1 18  ? 259.176 265.409 407.431 1.00 99.24  ? 18  THR C CA  1 
ATOM 3473 C C   . THR E 1 18  ? 258.609 264.456 406.390 1.00 99.24  ? 18  THR C C   1 
ATOM 3474 O O   . THR E 1 18  ? 257.394 264.287 406.270 1.00 99.24  ? 18  THR C O   1 
ATOM 3475 C CB  . THR E 1 18  ? 259.795 264.610 408.582 1.00 99.24  ? 18  THR C CB  1 
ATOM 3476 O OG1 . THR E 1 18  ? 260.863 263.800 408.077 1.00 99.24  ? 18  THR C OG1 1 
ATOM 3477 C CG2 . THR E 1 18  ? 258.751 263.716 409.227 1.00 99.24  ? 18  THR C CG2 1 
ATOM 3478 N N   . LEU E 1 19  ? 259.508 263.831 405.633 1.00 88.95  ? 19  LEU C N   1 
ATOM 3479 C CA  . LEU E 1 19  ? 259.126 262.862 404.619 1.00 88.95  ? 19  LEU C CA  1 
ATOM 3480 C C   . LEU E 1 19  ? 260.069 261.671 404.672 1.00 88.95  ? 19  LEU C C   1 
ATOM 3481 O O   . LEU E 1 19  ? 261.168 261.753 405.226 1.00 88.95  ? 19  LEU C O   1 
ATOM 3482 C CB  . LEU E 1 19  ? 259.149 263.456 403.204 1.00 88.95  ? 19  LEU C CB  1 
ATOM 3483 C CG  . LEU E 1 19  ? 260.514 263.689 402.554 1.00 88.95  ? 19  LEU C CG  1 
ATOM 3484 C CD1 . LEU E 1 19  ? 260.348 263.911 401.062 1.00 88.95  ? 19  LEU C CD1 1 
ATOM 3485 C CD2 . LEU E 1 19  ? 261.244 264.852 403.185 1.00 88.95  ? 19  LEU C CD2 1 
ATOM 3486 N N   . VAL E 1 20  ? 259.627 260.561 404.088 1.00 79.68  ? 20  VAL C N   1 
ATOM 3487 C CA  . VAL E 1 20  ? 260.426 259.348 403.996 1.00 79.68  ? 20  VAL C CA  1 
ATOM 3488 C C   . VAL E 1 20  ? 260.648 259.027 402.526 1.00 79.68  ? 20  VAL C C   1 
ATOM 3489 O O   . VAL E 1 20  ? 259.866 259.424 401.657 1.00 79.68  ? 20  VAL C O   1 
ATOM 3490 C CB  . VAL E 1 20  ? 259.760 258.159 404.720 1.00 79.68  ? 20  VAL C CB  1 
ATOM 3491 C CG1 . VAL E 1 20  ? 259.576 258.474 406.191 1.00 79.68  ? 20  VAL C CG1 1 
ATOM 3492 C CG2 . VAL E 1 20  ? 258.428 257.827 404.074 1.00 79.68  ? 20  VAL C CG2 1 
ATOM 3493 N N   . LEU E 1 21  ? 261.732 258.309 402.252 1.00 77.52  ? 21  LEU C N   1 
ATOM 3494 C CA  . LEU E 1 21  ? 262.114 257.947 400.895 1.00 77.52  ? 21  LEU C CA  1 
ATOM 3495 C C   . LEU E 1 21  ? 262.264 256.437 400.788 1.00 77.52  ? 21  LEU C C   1 
ATOM 3496 O O   . LEU E 1 21  ? 262.784 255.789 401.700 1.00 77.52  ? 21  LEU C O   1 
ATOM 3497 C CB  . LEU E 1 21  ? 263.421 258.629 400.485 1.00 77.52  ? 21  LEU C CB  1 
ATOM 3498 C CG  . LEU E 1 21  ? 263.324 259.976 399.766 1.00 77.52  ? 21  LEU C CG  1 
ATOM 3499 C CD1 . LEU E 1 21  ? 262.608 259.817 398.439 1.00 77.52  ? 21  LEU C CD1 1 
ATOM 3500 C CD2 . LEU E 1 21  ? 262.638 261.024 400.624 1.00 77.52  ? 21  LEU C CD2 1 
ATOM 3501 N N   . ASN E 1 22  ? 261.801 255.880 399.671 1.00 77.20  ? 22  ASN C N   1 
ATOM 3502 C CA  . ASN E 1 22  ? 261.908 254.453 399.418 1.00 77.20  ? 22  ASN C CA  1 
ATOM 3503 C C   . ASN E 1 22  ? 262.690 254.208 398.139 1.00 77.20  ? 22  ASN C C   1 
ATOM 3504 O O   . ASN E 1 22  ? 262.394 254.833 397.112 1.00 77.20  ? 22  ASN C O   1 
ATOM 3505 C CB  . ASN E 1 22  ? 260.520 253.819 399.307 1.00 77.20  ? 22  ASN C CB  1 
ATOM 3506 C CG  . ASN E 1 22  ? 259.861 253.628 400.654 1.00 77.20  ? 22  ASN C CG  1 
ATOM 3507 O OD1 . ASN E 1 22  ? 260.377 254.074 401.678 1.00 77.20  ? 22  ASN C OD1 1 
ATOM 3508 N ND2 . ASN E 1 22  ? 258.713 252.962 400.663 1.00 77.20  ? 22  ASN C ND2 1 
ATOM 3509 N N   . PRO E 1 23  ? 263.689 253.328 398.158 1.00 64.36  ? 23  PRO C N   1 
ATOM 3510 C CA  . PRO E 1 23  ? 264.438 253.036 396.930 1.00 64.36  ? 23  PRO C CA  1 
ATOM 3511 C C   . PRO E 1 23  ? 263.544 252.372 395.895 1.00 64.36  ? 23  PRO C C   1 
ATOM 3512 O O   . PRO E 1 23  ? 262.647 251.600 396.236 1.00 64.36  ? 23  PRO C O   1 
ATOM 3513 C CB  . PRO E 1 23  ? 265.545 252.092 397.409 1.00 64.36  ? 23  PRO C CB  1 
ATOM 3514 C CG  . PRO E 1 23  ? 264.956 251.431 398.609 1.00 64.36  ? 23  PRO C CG  1 
ATOM 3515 C CD  . PRO E 1 23  ? 264.138 252.495 399.285 1.00 64.36  ? 23  PRO C CD  1 
ATOM 3516 N N   . ARG E 1 24  ? 263.793 252.678 394.624 1.00 59.06  ? 24  ARG C N   1 
ATOM 3517 C CA  . ARG E 1 24  ? 263.024 252.102 393.530 1.00 59.06  ? 24  ARG C CA  1 
ATOM 3518 C C   . ARG E 1 24  ? 263.910 251.448 392.478 1.00 59.06  ? 24  ARG C C   1 
ATOM 3519 O O   . ARG E 1 24  ? 263.439 251.164 391.372 1.00 59.06  ? 24  ARG C O   1 
ATOM 3520 C CB  . ARG E 1 24  ? 262.132 253.169 392.892 1.00 59.06  ? 24  ARG C CB  1 
ATOM 3521 C CG  . ARG E 1 24  ? 260.851 252.621 392.283 1.00 59.06  ? 24  ARG C CG  1 
ATOM 3522 C CD  . ARG E 1 24  ? 259.896 253.737 391.882 1.00 59.06  ? 24  ARG C CD  1 
ATOM 3523 N NE  . ARG E 1 24  ? 259.240 254.360 393.027 1.00 59.06  ? 24  ARG C NE  1 
ATOM 3524 C CZ  . ARG E 1 24  ? 258.420 253.741 393.867 1.00 59.06  ? 24  ARG C CZ  1 
ATOM 3525 N NH1 . ARG E 1 24  ? 258.087 252.471 393.705 1.00 59.06  ? 24  ARG C NH1 1 
ATOM 3526 N NH2 . ARG E 1 24  ? 257.910 254.418 394.891 1.00 59.06  ? 24  ARG C NH2 1 
ATOM 3527 N N   . GLY E 1 25  ? 265.180 251.209 392.790 1.00 57.90  ? 25  GLY C N   1 
ATOM 3528 C CA  . GLY E 1 25  ? 266.044 250.435 391.920 1.00 57.90  ? 25  GLY C CA  1 
ATOM 3529 C C   . GLY E 1 25  ? 266.606 251.194 390.737 1.00 57.90  ? 25  GLY C C   1 
ATOM 3530 O O   . GLY E 1 25  ? 265.903 251.980 390.097 1.00 57.90  ? 25  GLY C O   1 
ATOM 3531 N N   . VAL E 1 26  ? 267.881 250.952 390.432 1.00 55.52  ? 26  VAL C N   1 
ATOM 3532 C CA  . VAL E 1 26  ? 268.519 251.599 389.294 1.00 55.52  ? 26  VAL C CA  1 
ATOM 3533 C C   . VAL E 1 26  ? 268.125 250.887 388.006 1.00 55.52  ? 26  VAL C C   1 
ATOM 3534 O O   . VAL E 1 26  ? 267.956 249.662 387.970 1.00 55.52  ? 26  VAL C O   1 
ATOM 3535 C CB  . VAL E 1 26  ? 270.047 251.614 389.485 1.00 55.52  ? 26  VAL C CB  1 
ATOM 3536 C CG1 . VAL E 1 26  ? 270.576 250.200 389.645 1.00 55.52  ? 26  VAL C CG1 1 
ATOM 3537 C CG2 . VAL E 1 26  ? 270.733 252.314 388.324 1.00 55.52  ? 26  VAL C CG2 1 
ATOM 3538 N N   . ASN E 1 27  ? 267.963 251.662 386.935 1.00 62.22  ? 27  ASN C N   1 
ATOM 3539 C CA  . ASN E 1 27  ? 267.693 251.084 385.631 1.00 62.22  ? 27  ASN C CA  1 
ATOM 3540 C C   . ASN E 1 27  ? 268.990 250.881 384.866 1.00 62.22  ? 27  ASN C C   1 
ATOM 3541 O O   . ASN E 1 27  ? 269.914 251.694 384.992 1.00 62.22  ? 27  ASN C O   1 
ATOM 3542 C CB  . ASN E 1 27  ? 266.732 251.969 384.823 1.00 62.22  ? 27  ASN C CB  1 
ATOM 3543 C CG  . ASN E 1 27  ? 267.245 253.382 384.637 1.00 62.22  ? 27  ASN C CG  1 
ATOM 3544 O OD1 . ASN E 1 27  ? 268.268 253.769 385.197 1.00 62.22  ? 27  ASN C OD1 1 
ATOM 3545 N ND2 . ASN E 1 27  ? 266.528 254.165 383.840 1.00 62.22  ? 27  ASN C ND2 1 
ATOM 3546 N N   . PRO E 1 28  ? 269.108 249.805 384.087 1.00 70.67  ? 28  PRO C N   1 
ATOM 3547 C CA  . PRO E 1 28  ? 270.394 249.530 383.423 1.00 70.67  ? 28  PRO C CA  1 
ATOM 3548 C C   . PRO E 1 28  ? 270.656 250.415 382.219 1.00 70.67  ? 28  PRO C C   1 
ATOM 3549 O O   . PRO E 1 28  ? 271.767 250.396 381.677 1.00 70.67  ? 28  PRO C O   1 
ATOM 3550 C CB  . PRO E 1 28  ? 270.284 248.053 383.016 1.00 70.67  ? 28  PRO C CB  1 
ATOM 3551 C CG  . PRO E 1 28  ? 268.988 247.548 383.546 1.00 70.67  ? 28  PRO C CG  1 
ATOM 3552 C CD  . PRO E 1 28  ? 268.146 248.699 383.968 1.00 70.67  ? 28  PRO C CD  1 
ATOM 3553 N N   . THR E 1 29  ? 269.658 251.180 381.774 1.00 70.60  ? 29  THR C N   1 
ATOM 3554 C CA  . THR E 1 29  ? 269.799 251.936 380.533 1.00 70.60  ? 29  THR C CA  1 
ATOM 3555 C C   . THR E 1 29  ? 270.927 252.957 380.624 1.00 70.60  ? 29  THR C C   1 
ATOM 3556 O O   . THR E 1 29  ? 271.781 253.035 379.734 1.00 70.60  ? 29  THR C O   1 
ATOM 3557 C CB  . THR E 1 29  ? 268.480 252.628 380.192 1.00 70.60  ? 29  THR C CB  1 
ATOM 3558 O OG1 . THR E 1 29  ? 268.136 253.542 381.240 1.00 70.60  ? 29  THR C OG1 1 
ATOM 3559 C CG2 . THR E 1 29  ? 267.368 251.602 380.034 1.00 70.60  ? 29  THR C CG2 1 
ATOM 3560 N N   . ASN E 1 30  ? 270.949 253.750 381.695 1.00 69.40  ? 30  ASN C N   1 
ATOM 3561 C CA  . ASN E 1 30  ? 271.916 254.834 381.834 1.00 69.40  ? 30  ASN C CA  1 
ATOM 3562 C C   . ASN E 1 30  ? 272.502 254.922 383.239 1.00 69.40  ? 30  ASN C C   1 
ATOM 3563 O O   . ASN E 1 30  ? 273.136 255.925 383.578 1.00 69.40  ? 30  ASN C O   1 
ATOM 3564 C CB  . ASN E 1 30  ? 271.274 256.164 381.441 1.00 69.40  ? 30  ASN C CB  1 
ATOM 3565 C CG  . ASN E 1 30  ? 269.877 256.320 382.001 1.00 69.40  ? 30  ASN C CG  1 
ATOM 3566 O OD1 . ASN E 1 30  ? 269.565 255.806 383.074 1.00 69.40  ? 30  ASN C OD1 1 
ATOM 3567 N ND2 . ASN E 1 30  ? 269.024 257.031 381.273 1.00 69.40  ? 30  ASN C ND2 1 
ATOM 3568 N N   . GLY E 1 31  ? 272.310 253.895 384.060 1.00 66.30  ? 31  GLY C N   1 
ATOM 3569 C CA  . GLY E 1 31  ? 272.889 253.894 385.394 1.00 66.30  ? 31  GLY C CA  1 
ATOM 3570 C C   . GLY E 1 31  ? 272.399 255.015 386.283 1.00 66.30  ? 31  GLY C C   1 
ATOM 3571 O O   . GLY E 1 31  ? 273.208 255.680 386.942 1.00 66.30  ? 31  GLY C O   1 
ATOM 3572 N N   . VAL E 1 32  ? 271.090 255.242 386.319 1.00 56.45  ? 32  VAL C N   1 
ATOM 3573 C CA  . VAL E 1 32  ? 270.490 256.312 387.106 1.00 56.45  ? 32  VAL C CA  1 
ATOM 3574 C C   . VAL E 1 32  ? 269.639 255.679 388.196 1.00 56.45  ? 32  VAL C C   1 
ATOM 3575 O O   . VAL E 1 32  ? 268.723 254.903 387.901 1.00 56.45  ? 32  VAL C O   1 
ATOM 3576 C CB  . VAL E 1 32  ? 269.646 257.252 386.235 1.00 56.45  ? 32  VAL C CB  1 
ATOM 3577 C CG1 . VAL E 1 32  ? 268.925 258.266 387.101 1.00 56.45  ? 32  VAL C CG1 1 
ATOM 3578 C CG2 . VAL E 1 32  ? 270.522 257.947 385.210 1.00 56.45  ? 32  VAL C CG2 1 
ATOM 3579 N N   . ALA E 1 33  ? 269.933 256.016 389.448 1.00 52.65  ? 33  ALA C N   1 
ATOM 3580 C CA  . ALA E 1 33  ? 269.160 255.502 390.565 1.00 52.65  ? 33  ALA C CA  1 
ATOM 3581 C C   . ALA E 1 33  ? 267.807 256.204 390.644 1.00 52.65  ? 33  ALA C C   1 
ATOM 3582 O O   . ALA E 1 33  ? 267.474 257.067 389.830 1.00 52.65  ? 33  ALA C O   1 
ATOM 3583 C CB  . ALA E 1 33  ? 269.926 255.675 391.874 1.00 52.65  ? 33  ALA C CB  1 
ATOM 3584 N N   . SER E 1 34  ? 267.014 255.817 391.640 1.00 56.21  ? 34  SER C N   1 
ATOM 3585 C CA  . SER E 1 34  ? 265.712 256.428 391.858 1.00 56.21  ? 34  SER C CA  1 
ATOM 3586 C C   . SER E 1 34  ? 265.294 256.250 393.309 1.00 56.21  ? 34  SER C C   1 
ATOM 3587 O O   . SER E 1 34  ? 265.501 255.194 393.909 1.00 56.21  ? 34  SER C O   1 
ATOM 3588 C CB  . SER E 1 34  ? 264.646 255.829 390.934 1.00 56.21  ? 34  SER C CB  1 
ATOM 3589 O OG  . SER E 1 34  ? 264.881 256.192 389.586 1.00 56.21  ? 34  SER C OG  1 
ATOM 3590 N N   . LEU E 1 35  ? 264.699 257.301 393.864 1.00 61.70  ? 35  LEU C N   1 
ATOM 3591 C CA  . LEU E 1 35  ? 264.124 257.269 395.199 1.00 61.70  ? 35  LEU C CA  1 
ATOM 3592 C C   . LEU E 1 35  ? 262.755 257.925 395.135 1.00 61.70  ? 35  LEU C C   1 
ATOM 3593 O O   . LEU E 1 35  ? 262.473 258.721 394.237 1.00 61.70  ? 35  LEU C O   1 
ATOM 3594 C CB  . LEU E 1 35  ? 265.017 257.979 396.223 1.00 61.70  ? 35  LEU C CB  1 
ATOM 3595 C CG  . LEU E 1 35  ? 266.129 257.147 396.863 1.00 61.70  ? 35  LEU C CG  1 
ATOM 3596 C CD1 . LEU E 1 35  ? 267.327 257.041 395.939 1.00 61.70  ? 35  LEU C CD1 1 
ATOM 3597 C CD2 . LEU E 1 35  ? 266.537 257.748 398.197 1.00 61.70  ? 35  LEU C CD2 1 
ATOM 3598 N N   . SER E 1 36  ? 261.898 257.589 396.093 1.00 75.86  ? 36  SER C N   1 
ATOM 3599 C CA  . SER E 1 36  ? 260.509 258.010 395.997 1.00 75.86  ? 36  SER C CA  1 
ATOM 3600 C C   . SER E 1 36  ? 259.824 257.880 397.349 1.00 75.86  ? 36  SER C C   1 
ATOM 3601 O O   . SER E 1 36  ? 260.382 257.339 398.305 1.00 75.86  ? 36  SER C O   1 
ATOM 3602 C CB  . SER E 1 36  ? 259.769 257.192 394.942 1.00 75.86  ? 36  SER C CB  1 
ATOM 3603 O OG  . SER E 1 36  ? 258.392 257.471 394.994 1.00 75.86  ? 36  SER C OG  1 
ATOM 3604 N N   . GLN E 1 37  ? 258.594 258.388 397.407 1.00 86.99  ? 37  GLN C N   1 
ATOM 3605 C CA  . GLN E 1 37  ? 257.728 258.279 398.573 1.00 86.99  ? 37  GLN C CA  1 
ATOM 3606 C C   . GLN E 1 37  ? 256.514 257.427 398.229 1.00 86.99  ? 37  GLN C C   1 
ATOM 3607 O O   . GLN E 1 37  ? 255.865 257.642 397.203 1.00 86.99  ? 37  GLN C O   1 
ATOM 3608 C CB  . GLN E 1 37  ? 257.272 259.658 399.052 1.00 86.99  ? 37  GLN C CB  1 
ATOM 3609 C CG  . GLN E 1 37  ? 256.553 259.635 400.386 1.00 86.99  ? 37  GLN C CG  1 
ATOM 3610 C CD  . GLN E 1 37  ? 255.961 260.981 400.746 1.00 86.99  ? 37  GLN C CD  1 
ATOM 3611 O OE1 . GLN E 1 37  ? 256.072 261.941 399.987 1.00 86.99  ? 37  GLN C OE1 1 
ATOM 3612 N NE2 . GLN E 1 37  ? 255.327 261.058 401.910 1.00 86.99  ? 37  GLN C NE2 1 
ATOM 3613 N N   . ALA E 1 38  ? 256.193 256.472 399.102 1.00 91.82  ? 38  ALA C N   1 
ATOM 3614 C CA  . ALA E 1 38  ? 255.173 255.482 398.764 1.00 91.82  ? 38  ALA C CA  1 
ATOM 3615 C C   . ALA E 1 38  ? 253.789 255.913 399.234 1.00 91.82  ? 38  ALA C C   1 
ATOM 3616 O O   . ALA E 1 38  ? 252.853 255.107 399.243 1.00 91.82  ? 38  ALA C O   1 
ATOM 3617 C CB  . ALA E 1 38  ? 255.542 254.127 399.365 1.00 91.82  ? 38  ALA C CB  1 
ATOM 3618 N N   . GLY E 1 39  ? 253.642 257.177 399.632 1.00 98.64  ? 39  GLY C N   1 
ATOM 3619 C CA  . GLY E 1 39  ? 252.417 257.596 400.299 1.00 98.64  ? 39  GLY C CA  1 
ATOM 3620 C C   . GLY E 1 39  ? 251.177 257.486 399.430 1.00 98.64  ? 39  GLY C C   1 
ATOM 3621 O O   . GLY E 1 39  ? 250.145 256.969 399.865 1.00 98.64  ? 39  GLY C O   1 
ATOM 3622 N N   . ALA E 1 40  ? 251.257 257.967 398.189 1.00 99.97  ? 40  ALA C N   1 
ATOM 3623 C CA  . ALA E 1 40  ? 250.047 258.193 397.404 1.00 99.97  ? 40  ALA C CA  1 
ATOM 3624 C C   . ALA E 1 40  ? 250.029 257.454 396.070 1.00 99.97  ? 40  ALA C C   1 
ATOM 3625 O O   . ALA E 1 40  ? 250.813 256.527 395.846 1.00 99.97  ? 40  ALA C O   1 
ATOM 3626 C CB  . ALA E 1 40  ? 249.857 259.691 397.160 1.00 99.97  ? 40  ALA C CB  1 
ATOM 3627 N N   . VAL E 1 41  ? 249.106 257.856 395.197 1.00 92.00  ? 41  VAL C N   1 
ATOM 3628 C CA  . VAL E 1 41  ? 248.998 257.303 393.843 1.00 92.00  ? 41  VAL C CA  1 
ATOM 3629 C C   . VAL E 1 41  ? 250.322 257.497 393.117 1.00 92.00  ? 41  VAL C C   1 
ATOM 3630 O O   . VAL E 1 41  ? 250.968 258.552 393.283 1.00 92.00  ? 41  VAL C O   1 
ATOM 3631 C CB  . VAL E 1 41  ? 247.848 257.987 393.083 1.00 92.00  ? 41  VAL C CB  1 
ATOM 3632 C CG1 . VAL E 1 41  ? 247.517 257.246 391.797 1.00 92.00  ? 41  VAL C CG1 1 
ATOM 3633 C CG2 . VAL E 1 41  ? 246.622 258.101 393.972 1.00 92.00  ? 41  VAL C CG2 1 
ATOM 3634 N N   . PRO E 1 42  ? 250.783 256.532 392.317 1.00 84.36  ? 42  PRO C N   1 
ATOM 3635 C CA  . PRO E 1 42  ? 252.107 256.665 391.687 1.00 84.36  ? 42  PRO C CA  1 
ATOM 3636 C C   . PRO E 1 42  ? 252.287 257.914 390.844 1.00 84.36  ? 42  PRO C C   1 
ATOM 3637 O O   . PRO E 1 42  ? 253.404 258.441 390.786 1.00 84.36  ? 42  PRO C O   1 
ATOM 3638 C CB  . PRO E 1 42  ? 252.209 255.399 390.831 1.00 84.36  ? 42  PRO C CB  1 
ATOM 3639 C CG  . PRO E 1 42  ? 251.400 254.406 391.573 1.00 84.36  ? 42  PRO C CG  1 
ATOM 3640 C CD  . PRO E 1 42  ? 250.251 255.166 392.180 1.00 84.36  ? 42  PRO C CD  1 
ATOM 3641 N N   . ALA E 1 43  ? 251.241 258.403 390.178 1.00 83.74  ? 43  ALA C N   1 
ATOM 3642 C CA  . ALA E 1 43  ? 251.384 259.636 389.412 1.00 83.74  ? 43  ALA C CA  1 
ATOM 3643 C C   . ALA E 1 43  ? 251.676 260.819 390.324 1.00 83.74  ? 43  ALA C C   1 
ATOM 3644 O O   . ALA E 1 43  ? 252.491 261.686 389.990 1.00 83.74  ? 43  ALA C O   1 
ATOM 3645 C CB  . ALA E 1 43  ? 250.126 259.893 388.585 1.00 83.74  ? 43  ALA C CB  1 
ATOM 3646 N N   . LEU E 1 44  ? 251.023 260.869 391.484 1.00 84.96  ? 44  LEU C N   1 
ATOM 3647 C CA  . LEU E 1 44  ? 251.171 261.986 392.416 1.00 84.96  ? 44  LEU C CA  1 
ATOM 3648 C C   . LEU E 1 44  ? 252.170 261.606 393.507 1.00 84.96  ? 44  LEU C C   1 
ATOM 3649 O O   . LEU E 1 44  ? 251.840 261.451 394.684 1.00 84.96  ? 44  LEU C O   1 
ATOM 3650 C CB  . LEU E 1 44  ? 249.821 262.359 393.004 1.00 84.96  ? 44  LEU C CB  1 
ATOM 3651 C CG  . LEU E 1 44  ? 248.852 262.858 391.942 1.00 84.96  ? 44  LEU C CG  1 
ATOM 3652 C CD1 . LEU E 1 44  ? 247.489 263.121 392.552 1.00 84.96  ? 44  LEU C CD1 1 
ATOM 3653 C CD2 . LEU E 1 44  ? 249.417 264.082 391.255 1.00 84.96  ? 44  LEU C CD2 1 
ATOM 3654 N N   . GLU E 1 45  ? 253.422 261.459 393.089 1.00 85.88  ? 45  GLU C N   1 
ATOM 3655 C CA  . GLU E 1 45  ? 254.443 260.859 393.933 1.00 85.88  ? 45  GLU C CA  1 
ATOM 3656 C C   . GLU E 1 45  ? 255.746 261.630 393.798 1.00 85.88  ? 45  GLU C C   1 
ATOM 3657 O O   . GLU E 1 45  ? 256.240 261.831 392.684 1.00 85.88  ? 45  GLU C O   1 
ATOM 3658 C CB  . GLU E 1 45  ? 254.627 259.390 393.549 1.00 85.88  ? 45  GLU C CB  1 
ATOM 3659 C CG  . GLU E 1 45  ? 255.638 258.640 394.363 1.00 85.88  ? 45  GLU C CG  1 
ATOM 3660 C CD  . GLU E 1 45  ? 255.673 257.160 394.019 1.00 85.88  ? 45  GLU C CD  1 
ATOM 3661 O OE1 . GLU E 1 45  ? 254.795 256.703 393.262 1.00 85.88  ? 45  GLU C OE1 1 
ATOM 3662 O OE2 . GLU E 1 45  ? 256.573 256.450 394.512 1.00 85.88  ? 45  GLU C OE2 1 
ATOM 3663 N N   . LYS E 1 46  ? 256.298 262.059 394.931 1.00 73.86  ? 46  LYS C N   1 
ATOM 3664 C CA  . LYS E 1 46  ? 257.553 262.800 394.927 1.00 73.86  ? 46  LYS C CA  1 
ATOM 3665 C C   . LYS E 1 46  ? 258.697 261.881 394.521 1.00 73.86  ? 46  LYS C C   1 
ATOM 3666 O O   . LYS E 1 46  ? 258.779 260.737 394.978 1.00 73.86  ? 46  LYS C O   1 
ATOM 3667 C CB  . LYS E 1 46  ? 257.813 263.400 396.306 1.00 73.86  ? 46  LYS C CB  1 
ATOM 3668 C CG  . LYS E 1 46  ? 256.577 264.000 396.954 1.00 73.86  ? 46  LYS C CG  1 
ATOM 3669 C CD  . LYS E 1 46  ? 256.863 264.487 398.364 1.00 73.86  ? 46  LYS C CD  1 
ATOM 3670 C CE  . LYS E 1 46  ? 256.046 265.722 398.707 1.00 73.86  ? 46  LYS C CE  1 
ATOM 3671 N NZ  . LYS E 1 46  ? 256.591 266.959 398.090 1.00 73.86  ? 46  LYS C NZ  1 
ATOM 3672 N N   . ARG E 1 47  ? 259.583 262.378 393.662 1.00 67.25  ? 47  ARG C N   1 
ATOM 3673 C CA  . ARG E 1 47  ? 260.619 261.553 393.057 1.00 67.25  ? 47  ARG C CA  1 
ATOM 3674 C C   . ARG E 1 47  ? 261.981 262.210 393.224 1.00 67.25  ? 47  ARG C C   1 
ATOM 3675 O O   . ARG E 1 47  ? 262.116 263.423 393.039 1.00 67.25  ? 47  ARG C O   1 
ATOM 3676 C CB  . ARG E 1 47  ? 260.315 261.315 391.577 1.00 67.25  ? 47  ARG C CB  1 
ATOM 3677 C CG  . ARG E 1 47  ? 261.345 260.482 390.849 1.00 67.25  ? 47  ARG C CG  1 
ATOM 3678 C CD  . ARG E 1 47  ? 260.818 260.050 389.495 1.00 67.25  ? 47  ARG C CD  1 
ATOM 3679 N NE  . ARG E 1 47  ? 259.768 259.047 389.628 1.00 67.25  ? 47  ARG C NE  1 
ATOM 3680 C CZ  . ARG E 1 47  ? 258.489 259.259 389.353 1.00 67.25  ? 47  ARG C CZ  1 
ATOM 3681 N NH1 . ARG E 1 47  ? 258.059 260.435 388.927 1.00 67.25  ? 47  ARG C NH1 1 
ATOM 3682 N NH2 . ARG E 1 47  ? 257.618 258.266 389.512 1.00 67.25  ? 47  ARG C NH2 1 
ATOM 3683 N N   . VAL E 1 48  ? 262.983 261.406 393.575 1.00 55.06  ? 48  VAL C N   1 
ATOM 3684 C CA  . VAL E 1 48  ? 264.365 261.851 393.721 1.00 55.06  ? 48  VAL C CA  1 
ATOM 3685 C C   . VAL E 1 48  ? 265.251 260.921 392.905 1.00 55.06  ? 48  VAL C C   1 
ATOM 3686 O O   . VAL E 1 48  ? 265.131 259.694 393.007 1.00 55.06  ? 48  VAL C O   1 
ATOM 3687 C CB  . VAL E 1 48  ? 264.804 261.862 395.195 1.00 55.06  ? 48  VAL C CB  1 
ATOM 3688 C CG1 . VAL E 1 48  ? 266.206 262.427 395.323 1.00 55.06  ? 48  VAL C CG1 1 
ATOM 3689 C CG2 . VAL E 1 48  ? 263.825 262.653 396.039 1.00 55.06  ? 48  VAL C CG2 1 
ATOM 3690 N N   . THR E 1 49  ? 266.140 261.497 392.098 1.00 51.03  ? 49  THR C N   1 
ATOM 3691 C CA  . THR E 1 49  ? 267.024 260.730 391.229 1.00 51.03  ? 49  THR C CA  1 
ATOM 3692 C C   . THR E 1 49  ? 268.462 261.183 391.439 1.00 51.03  ? 49  THR C C   1 
ATOM 3693 O O   . THR E 1 49  ? 268.749 262.383 391.392 1.00 51.03  ? 49  THR C O   1 
ATOM 3694 C CB  . THR E 1 49  ? 266.631 260.893 389.760 1.00 51.03  ? 49  THR C CB  1 
ATOM 3695 O OG1 . THR E 1 49  ? 266.774 262.265 389.379 1.00 51.03  ? 49  THR C OG1 1 
ATOM 3696 C CG2 . THR E 1 49  ? 265.192 260.465 389.540 1.00 51.03  ? 49  THR C CG2 1 
ATOM 3697 N N   . VAL E 1 50  ? 269.358 260.226 391.665 1.00 46.19  ? 50  VAL C N   1 
ATOM 3698 C CA  . VAL E 1 50  ? 270.790 260.478 391.792 1.00 46.19  ? 50  VAL C CA  1 
ATOM 3699 C C   . VAL E 1 50  ? 271.522 259.570 390.813 1.00 46.19  ? 50  VAL C C   1 
ATOM 3700 O O   . VAL E 1 50  ? 271.211 258.377 390.713 1.00 46.19  ? 50  VAL C O   1 
ATOM 3701 C CB  . VAL E 1 50  ? 271.276 260.264 393.237 1.00 46.19  ? 50  VAL C CB  1 
ATOM 3702 C CG1 . VAL E 1 50  ? 270.924 258.876 393.727 1.00 46.19  ? 50  VAL C CG1 1 
ATOM 3703 C CG2 . VAL E 1 50  ? 272.770 260.484 393.327 1.00 46.19  ? 50  VAL C CG2 1 
ATOM 3704 N N   . SER E 1 51  ? 272.477 260.136 390.069 1.00 54.17  ? 51  SER C N   1 
ATOM 3705 C CA  . SER E 1 51  ? 273.157 259.421 388.989 1.00 54.17  ? 51  SER C CA  1 
ATOM 3706 C C   . SER E 1 51  ? 274.648 259.764 388.995 1.00 54.17  ? 51  SER C C   1 
ATOM 3707 O O   . SER E 1 51  ? 275.082 260.726 388.362 1.00 54.17  ? 51  SER C O   1 
ATOM 3708 C CB  . SER E 1 51  ? 272.525 259.750 387.641 1.00 54.17  ? 51  SER C CB  1 
ATOM 3709 O OG  . SER E 1 51  ? 272.796 261.091 387.272 1.00 54.17  ? 51  SER C OG  1 
ATOM 3710 N N   . VAL E 1 52  ? 275.439 258.958 389.705 1.00 61.67  ? 52  VAL C N   1 
ATOM 3711 C CA  . VAL E 1 52  ? 276.888 259.086 389.618 1.00 61.67  ? 52  VAL C CA  1 
ATOM 3712 C C   . VAL E 1 52  ? 277.356 258.502 388.296 1.00 61.67  ? 52  VAL C C   1 
ATOM 3713 O O   . VAL E 1 52  ? 276.961 257.395 387.914 1.00 61.67  ? 52  VAL C O   1 
ATOM 3714 C CB  . VAL E 1 52  ? 277.562 258.392 390.810 1.00 61.67  ? 52  VAL C CB  1 
ATOM 3715 C CG1 . VAL E 1 52  ? 279.067 258.365 390.622 1.00 61.67  ? 52  VAL C CG1 1 
ATOM 3716 C CG2 . VAL E 1 52  ? 277.200 259.099 392.103 1.00 61.67  ? 52  VAL C CG2 1 
ATOM 3717 N N   . SER E 1 53  ? 278.195 259.245 387.586 1.00 70.36  ? 53  SER C N   1 
ATOM 3718 C CA  . SER E 1 53  ? 278.642 258.837 386.267 1.00 70.36  ? 53  SER C CA  1 
ATOM 3719 C C   . SER E 1 53  ? 280.096 258.375 386.317 1.00 70.36  ? 53  SER C C   1 
ATOM 3720 O O   . SER E 1 53  ? 280.722 258.314 387.378 1.00 70.36  ? 53  SER C O   1 
ATOM 3721 C CB  . SER E 1 53  ? 278.450 259.980 385.271 1.00 70.36  ? 53  SER C CB  1 
ATOM 3722 O OG  . SER E 1 53  ? 278.679 259.539 383.944 1.00 70.36  ? 53  SER C OG  1 
ATOM 3723 N N   . GLN E 1 54  ? 280.638 258.040 385.150 1.00 88.39  ? 54  GLN C N   1 
ATOM 3724 C CA  . GLN E 1 54  ? 282.001 257.564 384.984 1.00 88.39  ? 54  GLN C CA  1 
ATOM 3725 C C   . GLN E 1 54  ? 282.645 258.335 383.842 1.00 88.39  ? 54  GLN C C   1 
ATOM 3726 O O   . GLN E 1 54  ? 281.943 258.808 382.940 1.00 88.39  ? 54  GLN C O   1 
ATOM 3727 C CB  . GLN E 1 54  ? 282.037 256.057 384.680 1.00 88.39  ? 54  GLN C CB  1 
ATOM 3728 C CG  . GLN E 1 54  ? 281.517 255.170 385.804 1.00 88.39  ? 54  GLN C CG  1 
ATOM 3729 C CD  . GLN E 1 54  ? 282.469 255.089 386.979 1.00 88.39  ? 54  GLN C CD  1 
ATOM 3730 O OE1 . GLN E 1 54  ? 283.687 255.064 386.807 1.00 88.39  ? 54  GLN C OE1 1 
ATOM 3731 N NE2 . GLN E 1 54  ? 281.917 255.039 388.184 1.00 88.39  ? 54  GLN C NE2 1 
ATOM 3732 N N   . PRO E 1 55  ? 283.978 258.482 383.851 1.00 89.75  ? 55  PRO C N   1 
ATOM 3733 C CA  . PRO E 1 55  ? 284.652 259.229 382.783 1.00 89.75  ? 55  PRO C CA  1 
ATOM 3734 C C   . PRO E 1 55  ? 284.593 258.510 381.439 1.00 89.75  ? 55  PRO C C   1 
ATOM 3735 O O   . PRO E 1 55  ? 284.378 259.167 380.420 1.00 89.75  ? 55  PRO C O   1 
ATOM 3736 C CB  . PRO E 1 55  ? 286.098 259.331 383.280 1.00 89.75  ? 55  PRO C CB  1 
ATOM 3737 C CG  . PRO E 1 55  ? 286.255 258.204 384.232 1.00 89.75  ? 55  PRO C CG  1 
ATOM 3738 C CD  . PRO E 1 55  ? 284.921 258.023 384.884 1.00 89.75  ? 55  PRO C CD  1 
ATOM 3739 N N   . ASN E 1 61  ? 286.917 263.340 383.764 1.00 72.59  ? 61  ASN C N   1 
ATOM 3740 C CA  . ASN E 1 61  ? 286.089 264.276 384.514 1.00 72.59  ? 61  ASN C CA  1 
ATOM 3741 C C   . ASN E 1 61  ? 284.734 263.666 384.867 1.00 72.59  ? 61  ASN C C   1 
ATOM 3742 O O   . ASN E 1 61  ? 283.987 263.234 383.993 1.00 72.59  ? 61  ASN C O   1 
ATOM 3743 C CB  . ASN E 1 61  ? 285.911 265.572 383.721 1.00 72.59  ? 61  ASN C CB  1 
ATOM 3744 C CG  . ASN E 1 61  ? 285.193 265.357 382.408 1.00 72.59  ? 61  ASN C CG  1 
ATOM 3745 O OD1 . ASN E 1 61  ? 283.984 265.557 382.309 1.00 72.59  ? 61  ASN C OD1 1 
ATOM 3746 N ND2 . ASN E 1 61  ? 285.936 264.942 381.390 1.00 72.59  ? 61  ASN C ND2 1 
ATOM 3747 N N   . TYR E 1 62  ? 284.432 263.621 386.161 1.00 69.86  ? 62  TYR C N   1 
ATOM 3748 C CA  . TYR E 1 62  ? 283.200 263.009 386.627 1.00 69.86  ? 62  TYR C CA  1 
ATOM 3749 C C   . TYR E 1 62  ? 282.022 263.962 386.455 1.00 69.86  ? 62  TYR C C   1 
ATOM 3750 O O   . TYR E 1 62  ? 282.181 265.164 386.232 1.00 69.86  ? 62  TYR C O   1 
ATOM 3751 C CB  . TYR E 1 62  ? 283.318 262.600 388.094 1.00 69.86  ? 62  TYR C CB  1 
ATOM 3752 C CG  . TYR E 1 62  ? 284.343 261.529 388.375 1.00 69.86  ? 62  TYR C CG  1 
ATOM 3753 C CD1 . TYR E 1 62  ? 284.937 260.818 387.344 1.00 69.86  ? 62  TYR C CD1 1 
ATOM 3754 C CD2 . TYR E 1 62  ? 284.707 261.222 389.677 1.00 69.86  ? 62  TYR C CD2 1 
ATOM 3755 C CE1 . TYR E 1 62  ? 285.872 259.840 387.603 1.00 69.86  ? 62  TYR C CE1 1 
ATOM 3756 C CE2 . TYR E 1 62  ? 285.639 260.244 389.944 1.00 69.86  ? 62  TYR C CE2 1 
ATOM 3757 C CZ  . TYR E 1 62  ? 286.218 259.556 388.903 1.00 69.86  ? 62  TYR C CZ  1 
ATOM 3758 O OH  . TYR E 1 62  ? 287.149 258.579 389.161 1.00 69.86  ? 62  TYR C OH  1 
ATOM 3759 N N   . LYS E 1 63  ? 280.818 263.403 386.564 1.00 62.82  ? 63  LYS C N   1 
ATOM 3760 C CA  . LYS E 1 63  ? 279.589 264.185 386.623 1.00 62.82  ? 63  LYS C CA  1 
ATOM 3761 C C   . LYS E 1 63  ? 278.658 263.526 387.624 1.00 62.82  ? 63  LYS C C   1 
ATOM 3762 O O   . LYS E 1 63  ? 278.278 262.366 387.446 1.00 62.82  ? 63  LYS C O   1 
ATOM 3763 C CB  . LYS E 1 63  ? 278.908 264.285 385.254 1.00 62.82  ? 63  LYS C CB  1 
ATOM 3764 C CG  . LYS E 1 63  ? 279.706 265.022 384.197 1.00 62.82  ? 63  LYS C CG  1 
ATOM 3765 C CD  . LYS E 1 63  ? 278.923 265.132 382.900 1.00 62.82  ? 63  LYS C CD  1 
ATOM 3766 C CE  . LYS E 1 63  ? 278.795 263.784 382.211 1.00 62.82  ? 63  LYS C CE  1 
ATOM 3767 N NZ  . LYS E 1 63  ? 280.111 263.267 381.744 1.00 62.82  ? 63  LYS C NZ  1 
ATOM 3768 N N   . VAL E 1 64  ? 278.296 264.257 388.673 1.00 51.70  ? 64  VAL C N   1 
ATOM 3769 C CA  . VAL E 1 64  ? 277.318 263.802 389.652 1.00 51.70  ? 64  VAL C CA  1 
ATOM 3770 C C   . VAL E 1 64  ? 276.097 264.696 389.520 1.00 51.70  ? 64  VAL C C   1 
ATOM 3771 O O   . VAL E 1 64  ? 276.186 265.911 389.734 1.00 51.70  ? 64  VAL C O   1 
ATOM 3772 C CB  . VAL E 1 64  ? 277.874 263.840 391.082 1.00 51.70  ? 64  VAL C CB  1 
ATOM 3773 C CG1 . VAL E 1 64  ? 276.744 263.769 392.090 1.00 51.70  ? 64  VAL C CG1 1 
ATOM 3774 C CG2 . VAL E 1 64  ? 278.849 262.698 391.296 1.00 51.70  ? 64  VAL C CG2 1 
ATOM 3775 N N   . GLN E 1 65  ? 274.962 264.101 389.164 1.00 50.87  ? 65  GLN C N   1 
ATOM 3776 C CA  . GLN E 1 65  ? 273.753 264.857 388.875 1.00 50.87  ? 65  GLN C CA  1 
ATOM 3777 C C   . GLN E 1 65  ? 272.613 264.353 389.745 1.00 50.87  ? 65  GLN C C   1 
ATOM 3778 O O   . GLN E 1 65  ? 272.276 263.166 389.706 1.00 50.87  ? 65  GLN C O   1 
ATOM 3779 C CB  . GLN E 1 65  ? 273.389 264.753 387.392 1.00 50.87  ? 65  GLN C CB  1 
ATOM 3780 C CG  . GLN E 1 65  ? 271.977 265.176 387.057 1.00 50.87  ? 65  GLN C CG  1 
ATOM 3781 C CD  . GLN E 1 65  ? 271.635 264.922 385.604 1.00 50.87  ? 65  GLN C CD  1 
ATOM 3782 O OE1 . GLN E 1 65  ? 270.613 264.314 385.290 1.00 50.87  ? 65  GLN C OE1 1 
ATOM 3783 N NE2 . GLN E 1 65  ? 272.495 265.386 384.706 1.00 50.87  ? 65  GLN C NE2 1 
ATOM 3784 N N   . VAL E 1 66  ? 272.024 265.256 390.523 1.00 45.67  ? 66  VAL C N   1 
ATOM 3785 C CA  . VAL E 1 66  ? 270.916 264.947 391.419 1.00 45.67  ? 66  VAL C CA  1 
ATOM 3786 C C   . VAL E 1 66  ? 269.719 265.785 391.001 1.00 45.67  ? 66  VAL C C   1 
ATOM 3787 O O   . VAL E 1 66  ? 269.817 267.014 390.911 1.00 45.67  ? 66  VAL C O   1 
ATOM 3788 C CB  . VAL E 1 66  ? 271.286 265.217 392.887 1.00 45.67  ? 66  VAL C CB  1 
ATOM 3789 C CG1 . VAL E 1 66  ? 270.045 265.200 393.757 1.00 45.67  ? 66  VAL C CG1 1 
ATOM 3790 C CG2 . VAL E 1 66  ? 272.296 264.199 393.374 1.00 45.67  ? 66  VAL C CG2 1 
ATOM 3791 N N   . LYS E 1 67  ? 268.592 265.126 390.746 1.00 48.54  ? 67  LYS C N   1 
ATOM 3792 C CA  . LYS E 1 67  ? 267.359 265.793 390.352 1.00 48.54  ? 67  LYS C CA  1 
ATOM 3793 C C   . LYS E 1 67  ? 266.254 265.433 391.331 1.00 48.54  ? 67  LYS C C   1 
ATOM 3794 O O   . LYS E 1 67  ? 266.023 264.252 391.605 1.00 48.54  ? 67  LYS C O   1 
ATOM 3795 C CB  . LYS E 1 67  ? 266.947 265.401 388.932 1.00 48.54  ? 67  LYS C CB  1 
ATOM 3796 C CG  . LYS E 1 67  ? 268.079 265.434 387.922 1.00 48.54  ? 67  LYS C CG  1 
ATOM 3797 C CD  . LYS E 1 67  ? 267.662 264.834 386.588 1.00 48.54  ? 67  LYS C CD  1 
ATOM 3798 C CE  . LYS E 1 67  ? 266.266 265.272 386.177 1.00 48.54  ? 67  LYS C CE  1 
ATOM 3799 N NZ  . LYS E 1 67  ? 266.129 266.754 386.154 1.00 48.54  ? 67  LYS C NZ  1 
ATOM 3800 N N   . ILE E 1 68  ? 265.575 266.450 391.855 1.00 53.91  ? 68  ILE C N   1 
ATOM 3801 C CA  . ILE E 1 68  ? 264.417 266.270 392.720 1.00 53.91  ? 68  ILE C CA  1 
ATOM 3802 C C   . ILE E 1 68  ? 263.259 267.062 392.133 1.00 53.91  ? 68  ILE C C   1 
ATOM 3803 O O   . ILE E 1 68  ? 263.437 268.209 391.708 1.00 53.91  ? 68  ILE C O   1 
ATOM 3804 C CB  . ILE E 1 68  ? 264.708 266.696 394.175 1.00 53.91  ? 68  ILE C CB  1 
ATOM 3805 C CG1 . ILE E 1 68  ? 263.496 266.431 395.071 1.00 53.91  ? 68  ILE C CG1 1 
ATOM 3806 C CG2 . ILE E 1 68  ? 265.155 268.141 394.255 1.00 53.91  ? 68  ILE C CG2 1 
ATOM 3807 C CD1 . ILE E 1 68  ? 263.788 266.560 396.552 1.00 53.91  ? 68  ILE C CD1 1 
ATOM 3808 N N   . GLN E 1 69  ? 262.085 266.438 392.070 1.00 70.13  ? 69  GLN C N   1 
ATOM 3809 C CA  . GLN E 1 69  ? 260.893 267.068 391.521 1.00 70.13  ? 69  GLN C CA  1 
ATOM 3810 C C   . GLN E 1 69  ? 259.702 266.749 392.412 1.00 70.13  ? 69  GLN C C   1 
ATOM 3811 O O   . GLN E 1 69  ? 259.653 265.681 393.029 1.00 70.13  ? 69  GLN C O   1 
ATOM 3812 C CB  . GLN E 1 69  ? 260.648 266.607 390.080 1.00 70.13  ? 69  GLN C CB  1 
ATOM 3813 C CG  . GLN E 1 69  ? 259.955 265.270 389.941 1.00 70.13  ? 69  GLN C CG  1 
ATOM 3814 C CD  . GLN E 1 69  ? 259.595 264.960 388.506 1.00 70.13  ? 69  GLN C CD  1 
ATOM 3815 O OE1 . GLN E 1 69  ? 260.461 264.914 387.634 1.00 70.13  ? 69  GLN C OE1 1 
ATOM 3816 N NE2 . GLN E 1 69  ? 258.312 264.738 388.252 1.00 70.13  ? 69  GLN C NE2 1 
ATOM 3817 N N   . ASN E 1 70  ? 258.756 267.683 392.492 1.00 76.31  ? 70  ASN C N   1 
ATOM 3818 C CA  . ASN E 1 70  ? 257.614 267.554 393.375 1.00 76.31  ? 70  ASN C CA  1 
ATOM 3819 C C   . ASN E 1 70  ? 256.334 267.919 392.636 1.00 76.31  ? 70  ASN C C   1 
ATOM 3820 O O   . ASN E 1 70  ? 256.180 269.071 392.209 1.00 76.31  ? 70  ASN C O   1 
ATOM 3821 C CB  . ASN E 1 70  ? 257.775 268.456 394.600 1.00 76.31  ? 70  ASN C CB  1 
ATOM 3822 C CG  . ASN E 1 70  ? 258.413 267.741 395.762 1.00 76.31  ? 70  ASN C CG  1 
ATOM 3823 O OD1 . ASN E 1 70  ? 258.426 266.514 395.814 1.00 76.31  ? 70  ASN C OD1 1 
ATOM 3824 N ND2 . ASN E 1 70  ? 258.938 268.503 396.712 1.00 76.31  ? 70  ASN C ND2 1 
ATOM 3825 N N   . PRO E 1 71  ? 255.404 266.986 392.464 1.00 79.30  ? 71  PRO C N   1 
ATOM 3826 C CA  . PRO E 1 71  ? 254.144 267.317 391.792 1.00 79.30  ? 71  PRO C CA  1 
ATOM 3827 C C   . PRO E 1 71  ? 253.045 267.714 392.764 1.00 79.30  ? 71  PRO C C   1 
ATOM 3828 O O   . PRO E 1 71  ? 252.947 267.159 393.862 1.00 79.30  ? 71  PRO C O   1 
ATOM 3829 C CB  . PRO E 1 71  ? 253.801 266.019 391.058 1.00 79.30  ? 71  PRO C CB  1 
ATOM 3830 C CG  . PRO E 1 71  ? 254.384 264.941 391.931 1.00 79.30  ? 71  PRO C CG  1 
ATOM 3831 C CD  . PRO E 1 71  ? 255.513 265.545 392.745 1.00 79.30  ? 71  PRO C CD  1 
ATOM 3832 N N   . THR E 1 72  ? 252.217 268.677 392.371 1.00 79.93  ? 72  THR C N   1 
ATOM 3833 C CA  . THR E 1 72  ? 251.055 269.094 393.143 1.00 79.93  ? 72  THR C CA  1 
ATOM 3834 C C   . THR E 1 72  ? 249.813 268.971 392.274 1.00 79.93  ? 72  THR C C   1 
ATOM 3835 O O   . THR E 1 72  ? 249.847 269.285 391.080 1.00 79.93  ? 72  THR C O   1 
ATOM 3836 C CB  . THR E 1 72  ? 251.197 270.531 393.645 1.00 79.93  ? 72  THR C CB  1 
ATOM 3837 O OG1 . THR E 1 72  ? 251.497 271.395 392.542 1.00 79.93  ? 72  THR C OG1 1 
ATOM 3838 C CG2 . THR E 1 72  ? 252.306 270.625 394.679 1.00 79.93  ? 72  THR C CG2 1 
ATOM 3839 N N   . ALA E 1 73  ? 248.717 268.513 392.873 1.00 87.90  ? 73  ALA C N   1 
ATOM 3840 C CA  . ALA E 1 73  ? 247.516 268.187 392.123 1.00 87.90  ? 73  ALA C CA  1 
ATOM 3841 C C   . ALA E 1 73  ? 246.298 268.871 392.720 1.00 87.90  ? 73  ALA C C   1 
ATOM 3842 O O   . ALA E 1 73  ? 246.254 269.195 393.909 1.00 87.90  ? 73  ALA C O   1 
ATOM 3843 C CB  . ALA E 1 73  ? 247.270 266.680 392.085 1.00 87.90  ? 73  ALA C CB  1 
ATOM 3844 N N   . CYS E 1 74  ? 245.302 269.077 391.863 1.00 108.00 ? 74  CYS C N   1 
ATOM 3845 C CA  . CYS E 1 74  ? 243.991 269.557 392.261 1.00 108.00 ? 74  CYS C CA  1 
ATOM 3846 C C   . CYS E 1 74  ? 242.933 268.642 391.660 1.00 108.00 ? 74  CYS C C   1 
ATOM 3847 O O   . CYS E 1 74  ? 243.153 267.994 390.634 1.00 108.00 ? 74  CYS C O   1 
ATOM 3848 C CB  . CYS E 1 74  ? 243.757 271.004 391.815 1.00 108.00 ? 74  CYS C CB  1 
ATOM 3849 S SG  . CYS E 1 74  ? 243.440 271.184 390.049 1.00 108.00 ? 74  CYS C SG  1 
ATOM 3850 N N   . THR E 1 75  ? 241.777 268.595 392.313 1.00 113.15 ? 75  THR C N   1 
ATOM 3851 C CA  . THR E 1 75  ? 240.695 267.703 391.913 1.00 113.15 ? 75  THR C CA  1 
ATOM 3852 C C   . THR E 1 75  ? 239.906 268.352 390.782 1.00 113.15 ? 75  THR C C   1 
ATOM 3853 O O   . THR E 1 75  ? 239.075 269.233 391.022 1.00 113.15 ? 75  THR C O   1 
ATOM 3854 C CB  . THR E 1 75  ? 239.786 267.391 393.098 1.00 113.15 ? 75  THR C CB  1 
ATOM 3855 O OG1 . THR E 1 75  ? 239.129 268.591 393.524 1.00 113.15 ? 75  THR C OG1 1 
ATOM 3856 C CG2 . THR E 1 75  ? 240.599 266.828 394.254 1.00 113.15 ? 75  THR C CG2 1 
ATOM 3857 N N   . ALA E 1 76  ? 240.168 267.919 389.552 1.00 116.31 ? 76  ALA C N   1 
ATOM 3858 C CA  . ALA E 1 76  ? 239.399 268.400 388.413 1.00 116.31 ? 76  ALA C CA  1 
ATOM 3859 C C   . ALA E 1 76  ? 237.953 267.939 388.535 1.00 116.31 ? 76  ALA C C   1 
ATOM 3860 O O   . ALA E 1 76  ? 237.686 266.790 388.899 1.00 116.31 ? 76  ALA C O   1 
ATOM 3861 C CB  . ALA E 1 76  ? 240.010 267.901 387.107 1.00 116.31 ? 76  ALA C CB  1 
ATOM 3862 N N   . ASN E 1 77  ? 237.017 268.843 388.242 1.00 127.69 ? 77  ASN C N   1 
ATOM 3863 C CA  . ASN E 1 77  ? 235.603 268.519 388.399 1.00 127.69 ? 77  ASN C CA  1 
ATOM 3864 C C   . ASN E 1 77  ? 235.162 267.440 387.417 1.00 127.69 ? 77  ASN C C   1 
ATOM 3865 O O   . ASN E 1 77  ? 234.396 266.539 387.777 1.00 127.69 ? 77  ASN C O   1 
ATOM 3866 C CB  . ASN E 1 77  ? 234.756 269.778 388.225 1.00 127.69 ? 77  ASN C CB  1 
ATOM 3867 C CG  . ASN E 1 77  ? 233.663 269.891 389.265 1.00 127.69 ? 77  ASN C CG  1 
ATOM 3868 O OD1 . ASN E 1 77  ? 233.785 269.362 390.369 1.00 127.69 ? 77  ASN C OD1 1 
ATOM 3869 N ND2 . ASN E 1 77  ? 232.585 270.584 388.918 1.00 127.69 ? 77  ASN C ND2 1 
ATOM 3870 N N   . GLY E 1 78  ? 235.632 267.518 386.171 1.00 128.00 ? 78  GLY C N   1 
ATOM 3871 C CA  . GLY E 1 78  ? 235.153 266.600 385.149 1.00 128.00 ? 78  GLY C CA  1 
ATOM 3872 C C   . GLY E 1 78  ? 235.526 265.155 385.424 1.00 128.00 ? 78  GLY C C   1 
ATOM 3873 O O   . GLY E 1 78  ? 234.690 264.254 385.319 1.00 128.00 ? 78  GLY C O   1 
ATOM 3874 N N   . SER E 1 79  ? 236.782 264.914 385.784 1.00 121.18 ? 79  SER C N   1 
ATOM 3875 C CA  . SER E 1 79  ? 237.304 263.567 385.964 1.00 121.18 ? 79  SER C CA  1 
ATOM 3876 C C   . SER E 1 79  ? 237.495 263.282 387.446 1.00 121.18 ? 79  SER C C   1 
ATOM 3877 O O   . SER E 1 79  ? 238.035 264.116 388.179 1.00 121.18 ? 79  SER C O   1 
ATOM 3878 C CB  . SER E 1 79  ? 238.626 263.389 385.215 1.00 121.18 ? 79  SER C CB  1 
ATOM 3879 O OG  . SER E 1 79  ? 238.435 263.518 383.817 1.00 121.18 ? 79  SER C OG  1 
ATOM 3880 N N   . CYS E 1 80  ? 237.049 262.102 387.882 1.00 117.26 ? 80  CYS C N   1 
ATOM 3881 C CA  . CYS E 1 80  ? 237.161 261.743 389.292 1.00 117.26 ? 80  CYS C CA  1 
ATOM 3882 C C   . CYS E 1 80  ? 238.617 261.593 389.715 1.00 117.26 ? 80  CYS C C   1 
ATOM 3883 O O   . CYS E 1 80  ? 238.996 262.008 390.816 1.00 117.26 ? 80  CYS C O   1 
ATOM 3884 C CB  . CYS E 1 80  ? 236.388 260.455 389.567 1.00 117.26 ? 80  CYS C CB  1 
ATOM 3885 S SG  . CYS E 1 80  ? 236.797 259.094 388.452 1.00 117.26 ? 80  CYS C SG  1 
ATOM 3886 N N   . ASP E 1 81  ? 239.442 260.998 388.864 1.00 116.21 ? 81  ASP C N   1 
ATOM 3887 C CA  . ASP E 1 81  ? 240.840 260.776 389.219 1.00 116.21 ? 81  ASP C CA  1 
ATOM 3888 C C   . ASP E 1 81  ? 241.613 262.093 389.263 1.00 116.21 ? 81  ASP C C   1 
ATOM 3889 O O   . ASP E 1 81  ? 241.377 262.977 388.432 1.00 116.21 ? 81  ASP C O   1 
ATOM 3890 C CB  . ASP E 1 81  ? 241.487 259.776 388.252 1.00 116.21 ? 81  ASP C CB  1 
ATOM 3891 C CG  . ASP E 1 81  ? 241.518 260.259 386.806 1.00 116.21 ? 81  ASP C CG  1 
ATOM 3892 O OD1 . ASP E 1 81  ? 241.005 261.352 386.499 1.00 116.21 ? 81  ASP C OD1 1 
ATOM 3893 O OD2 . ASP E 1 81  ? 242.071 259.526 385.961 1.00 116.21 ? 81  ASP C OD2 1 
ATOM 3894 N N   . PRO E 1 82  ? 242.496 262.283 390.240 1.00 110.66 ? 82  PRO C N   1 
ATOM 3895 C CA  . PRO E 1 82  ? 243.308 263.505 390.270 1.00 110.66 ? 82  PRO C CA  1 
ATOM 3896 C C   . PRO E 1 82  ? 244.284 263.547 389.104 1.00 110.66 ? 82  PRO C C   1 
ATOM 3897 O O   . PRO E 1 82  ? 244.704 262.512 388.582 1.00 110.66 ? 82  PRO C O   1 
ATOM 3898 C CB  . PRO E 1 82  ? 244.040 263.412 391.613 1.00 110.66 ? 82  PRO C CB  1 
ATOM 3899 C CG  . PRO E 1 82  ? 243.222 262.473 392.432 1.00 110.66 ? 82  PRO C CG  1 
ATOM 3900 C CD  . PRO E 1 82  ? 242.667 261.480 391.461 1.00 110.66 ? 82  PRO C CD  1 
ATOM 3901 N N   . SER E 1 83  ? 244.642 264.760 388.695 1.00 98.43  ? 83  SER C N   1 
ATOM 3902 C CA  . SER E 1 83  ? 245.578 264.976 387.604 1.00 98.43  ? 83  SER C CA  1 
ATOM 3903 C C   . SER E 1 83  ? 246.683 265.925 388.047 1.00 98.43  ? 83  SER C C   1 
ATOM 3904 O O   . SER E 1 83  ? 246.489 266.757 388.938 1.00 98.43  ? 83  SER C O   1 
ATOM 3905 C CB  . SER E 1 83  ? 244.872 265.540 386.369 1.00 98.43  ? 83  SER C CB  1 
ATOM 3906 O OG  . SER E 1 83  ? 245.796 265.781 385.323 1.00 98.43  ? 83  SER C OG  1 
ATOM 3907 N N   . VAL E 1 84  ? 247.847 265.794 387.416 1.00 93.44  ? 84  VAL C N   1 
ATOM 3908 C CA  . VAL E 1 84  ? 248.995 266.636 387.735 1.00 93.44  ? 84  VAL C CA  1 
ATOM 3909 C C   . VAL E 1 84  ? 248.733 268.035 387.184 1.00 93.44  ? 84  VAL C C   1 
ATOM 3910 O O   . VAL E 1 84  ? 248.420 268.204 386.003 1.00 93.44  ? 84  VAL C O   1 
ATOM 3911 C CB  . VAL E 1 84  ? 250.298 266.049 387.178 1.00 93.44  ? 84  VAL C CB  1 
ATOM 3912 C CG1 . VAL E 1 84  ? 250.672 264.796 387.940 1.00 93.44  ? 84  VAL C CG1 1 
ATOM 3913 C CG2 . VAL E 1 84  ? 250.157 265.726 385.699 1.00 93.44  ? 84  VAL C CG2 1 
ATOM 3914 N N   . THR E 1 85  ? 248.843 269.045 388.048 1.00 86.82  ? 85  THR C N   1 
ATOM 3915 C CA  . THR E 1 85  ? 248.589 270.415 387.615 1.00 86.82  ? 85  THR C CA  1 
ATOM 3916 C C   . THR E 1 85  ? 249.878 271.113 387.207 1.00 86.82  ? 85  THR C C   1 
ATOM 3917 O O   . THR E 1 85  ? 249.969 271.685 386.115 1.00 86.82  ? 85  THR C O   1 
ATOM 3918 C CB  . THR E 1 85  ? 247.890 271.195 388.727 1.00 86.82  ? 85  THR C CB  1 
ATOM 3919 O OG1 . THR E 1 85  ? 246.644 270.564 389.045 1.00 86.82  ? 85  THR C OG1 1 
ATOM 3920 C CG2 . THR E 1 85  ? 247.635 272.626 388.288 1.00 86.82  ? 85  THR C CG2 1 
ATOM 3921 N N   . ARG E 1 86  ? 250.886 271.077 388.073 1.00 82.74  ? 86  ARG C N   1 
ATOM 3922 C CA  . ARG E 1 86  ? 252.148 271.751 387.812 1.00 82.74  ? 86  ARG C CA  1 
ATOM 3923 C C   . ARG E 1 86  ? 253.258 270.983 388.509 1.00 82.74  ? 86  ARG C C   1 
ATOM 3924 O O   . ARG E 1 86  ? 253.045 270.349 389.545 1.00 82.74  ? 86  ARG C O   1 
ATOM 3925 C CB  . ARG E 1 86  ? 252.103 273.208 388.279 1.00 82.74  ? 86  ARG C CB  1 
ATOM 3926 C CG  . ARG E 1 86  ? 251.607 273.373 389.703 1.00 82.74  ? 86  ARG C CG  1 
ATOM 3927 C CD  . ARG E 1 86  ? 251.634 274.825 390.135 1.00 82.74  ? 86  ARG C CD  1 
ATOM 3928 N NE  . ARG E 1 86  ? 251.631 274.956 391.586 1.00 82.74  ? 86  ARG C NE  1 
ATOM 3929 C CZ  . ARG E 1 86  ? 250.532 275.006 392.326 1.00 82.74  ? 86  ARG C CZ  1 
ATOM 3930 N NH1 . ARG E 1 86  ? 249.329 274.941 391.781 1.00 82.74  ? 86  ARG C NH1 1 
ATOM 3931 N NH2 . ARG E 1 86  ? 250.644 275.122 393.646 1.00 82.74  ? 86  ARG C NH2 1 
ATOM 3932 N N   . GLN E 1 87  ? 254.452 271.057 387.930 1.00 75.26  ? 87  GLN C N   1 
ATOM 3933 C CA  . GLN E 1 87  ? 255.560 270.220 388.354 1.00 75.26  ? 87  GLN C CA  1 
ATOM 3934 C C   . GLN E 1 87  ? 256.737 271.115 388.717 1.00 75.26  ? 87  GLN C C   1 
ATOM 3935 O O   . GLN E 1 87  ? 257.168 271.951 387.920 1.00 75.26  ? 87  GLN C O   1 
ATOM 3936 C CB  . GLN E 1 87  ? 255.938 269.230 387.241 1.00 75.26  ? 87  GLN C CB  1 
ATOM 3937 C CG  . GLN E 1 87  ? 257.030 268.240 387.589 1.00 75.26  ? 87  GLN C CG  1 
ATOM 3938 C CD  . GLN E 1 87  ? 256.637 267.330 388.734 1.00 75.26  ? 87  GLN C CD  1 
ATOM 3939 O OE1 . GLN E 1 87  ? 257.105 267.493 389.860 1.00 75.26  ? 87  GLN C OE1 1 
ATOM 3940 N NE2 . GLN E 1 87  ? 255.759 266.375 388.455 1.00 75.26  ? 87  GLN C NE2 1 
ATOM 3941 N N   . ALA E 1 88  ? 257.255 270.932 389.930 1.00 69.04  ? 88  ALA C N   1 
ATOM 3942 C CA  . ALA E 1 88  ? 258.297 271.793 390.481 1.00 69.04  ? 88  ALA C CA  1 
ATOM 3943 C C   . ALA E 1 88  ? 259.642 271.088 390.360 1.00 69.04  ? 88  ALA C C   1 
ATOM 3944 O O   . ALA E 1 88  ? 260.009 270.286 391.224 1.00 69.04  ? 88  ALA C O   1 
ATOM 3945 C CB  . ALA E 1 88  ? 257.993 272.147 391.934 1.00 69.04  ? 88  ALA C CB  1 
ATOM 3946 N N   . TYR E 1 89  ? 260.378 271.393 389.296 1.00 66.36  ? 89  TYR C N   1 
ATOM 3947 C CA  . TYR E 1 89  ? 261.645 270.735 389.028 1.00 66.36  ? 89  TYR C CA  1 
ATOM 3948 C C   . TYR E 1 89  ? 262.735 271.242 389.969 1.00 66.36  ? 89  TYR C C   1 
ATOM 3949 O O   . TYR E 1 89  ? 262.540 272.169 390.757 1.00 66.36  ? 89  TYR C O   1 
ATOM 3950 C CB  . TYR E 1 89  ? 262.080 270.961 387.581 1.00 66.36  ? 89  TYR C CB  1 
ATOM 3951 C CG  . TYR E 1 89  ? 261.203 270.315 386.534 1.00 66.36  ? 89  TYR C CG  1 
ATOM 3952 C CD1 . TYR E 1 89  ? 259.860 270.643 386.418 1.00 66.36  ? 89  TYR C CD1 1 
ATOM 3953 C CD2 . TYR E 1 89  ? 261.726 269.383 385.651 1.00 66.36  ? 89  TYR C CD2 1 
ATOM 3954 C CE1 . TYR E 1 89  ? 259.064 270.058 385.459 1.00 66.36  ? 89  TYR C CE1 1 
ATOM 3955 C CE2 . TYR E 1 89  ? 260.937 268.792 384.689 1.00 66.36  ? 89  TYR C CE2 1 
ATOM 3956 C CZ  . TYR E 1 89  ? 259.606 269.133 384.598 1.00 66.36  ? 89  TYR C CZ  1 
ATOM 3957 O OH  . TYR E 1 89  ? 258.814 268.545 383.640 1.00 66.36  ? 89  TYR C OH  1 
ATOM 3958 N N   . ALA E 1 90  ? 263.898 270.601 389.874 1.00 53.91  ? 90  ALA C N   1 
ATOM 3959 C CA  . ALA E 1 90  ? 265.128 271.058 390.504 1.00 53.91  ? 90  ALA C CA  1 
ATOM 3960 C C   . ALA E 1 90  ? 266.277 270.265 389.904 1.00 53.91  ? 90  ALA C C   1 
ATOM 3961 O O   . ALA E 1 90  ? 266.088 269.141 389.435 1.00 53.91  ? 90  ALA C O   1 
ATOM 3962 C CB  . ALA E 1 90  ? 265.104 270.896 392.027 1.00 53.91  ? 90  ALA C CB  1 
ATOM 3963 N N   . ASP E 1 91  ? 267.469 270.854 389.918 1.00 51.28  ? 91  ASP C N   1 
ATOM 3964 C CA  . ASP E 1 91  ? 268.610 270.224 389.271 1.00 51.28  ? 91  ASP C CA  1 
ATOM 3965 C C   . ASP E 1 91  ? 269.888 270.595 390.005 1.00 51.28  ? 91  ASP C C   1 
ATOM 3966 O O   . ASP E 1 91  ? 270.122 271.766 390.312 1.00 51.28  ? 91  ASP C O   1 
ATOM 3967 C CB  . ASP E 1 91  ? 268.707 270.640 387.799 1.00 51.28  ? 91  ASP C CB  1 
ATOM 3968 C CG  . ASP E 1 91  ? 269.630 269.745 386.996 1.00 51.28  ? 91  ASP C CG  1 
ATOM 3969 O OD1 . ASP E 1 91  ? 270.727 269.407 387.490 1.00 51.28  ? 91  ASP C OD1 1 
ATOM 3970 O OD2 . ASP E 1 91  ? 269.256 269.375 385.864 1.00 51.28  ? 91  ASP C OD2 1 
ATOM 3971 N N   . VAL E 1 92  ? 270.711 269.586 390.274 1.00 46.10  ? 92  VAL C N   1 
ATOM 3972 C CA  . VAL E 1 92  ? 272.046 269.767 390.826 1.00 46.10  ? 92  VAL C CA  1 
ATOM 3973 C C   . VAL E 1 92  ? 273.010 268.962 389.970 1.00 46.10  ? 92  VAL C C   1 
ATOM 3974 O O   . VAL E 1 92  ? 272.821 267.756 389.788 1.00 46.10  ? 92  VAL C O   1 
ATOM 3975 C CB  . VAL E 1 92  ? 272.126 269.322 392.297 1.00 46.10  ? 92  VAL C CB  1 
ATOM 3976 C CG1 . VAL E 1 92  ? 273.570 269.283 392.757 1.00 46.10  ? 92  VAL C CG1 1 
ATOM 3977 C CG2 . VAL E 1 92  ? 271.310 270.255 393.172 1.00 46.10  ? 92  VAL C CG2 1 
ATOM 3978 N N   . THR E 1 93  ? 274.044 269.628 389.440 1.00 50.14  ? 93  THR C N   1 
ATOM 3979 C CA  . THR E 1 93  ? 274.984 269.002 388.516 1.00 50.14  ? 93  THR C CA  1 
ATOM 3980 C C   . THR E 1 93  ? 276.425 269.280 388.966 1.00 50.14  ? 93  THR C C   1 
ATOM 3981 O O   . THR E 1 93  ? 277.081 270.241 388.571 1.00 50.14  ? 93  THR C O   1 
ATOM 3982 C CB  . THR E 1 93  ? 274.733 269.464 387.076 1.00 50.14  ? 93  THR C CB  1 
ATOM 3983 O OG1 . THR E 1 93  ? 275.754 268.947 386.213 1.00 50.14  ? 93  THR C OG1 1 
ATOM 3984 C CG2 . THR E 1 93  ? 274.661 270.988 386.975 1.00 50.14  ? 93  THR C CG2 1 
ATOM 3985 N N   . PHE E 1 94  ? 276.946 268.402 389.818 1.00 47.03  ? 94  PHE C N   1 
ATOM 3986 C CA  . PHE E 1 94  ? 278.335 268.507 390.232 1.00 47.03  ? 94  PHE C CA  1 
ATOM 3987 C C   . PHE E 1 94  ? 279.264 268.147 389.077 1.00 47.03  ? 94  PHE C C   1 
ATOM 3988 O O   . PHE E 1 94  ? 278.880 267.473 388.119 1.00 47.03  ? 94  PHE C O   1 
ATOM 3989 C CB  . PHE E 1 94  ? 278.614 267.592 391.421 1.00 47.03  ? 94  PHE C CB  1 
ATOM 3990 C CG  . PHE E 1 94  ? 277.961 268.035 392.693 1.00 47.03  ? 94  PHE C CG  1 
ATOM 3991 C CD1 . PHE E 1 94  ? 277.472 269.319 392.824 1.00 47.03  ? 94  PHE C CD1 1 
ATOM 3992 C CD2 . PHE E 1 94  ? 277.837 267.165 393.760 1.00 47.03  ? 94  PHE C CD2 1 
ATOM 3993 C CE1 . PHE E 1 94  ? 276.874 269.726 393.995 1.00 47.03  ? 94  PHE C CE1 1 
ATOM 3994 C CE2 . PHE E 1 94  ? 277.239 267.567 394.932 1.00 47.03  ? 94  PHE C CE2 1 
ATOM 3995 C CZ  . PHE E 1 94  ? 276.756 268.849 395.049 1.00 47.03  ? 94  PHE C CZ  1 
ATOM 3996 N N   . SER E 1 95  ? 280.503 268.618 389.174 1.00 57.87  ? 95  SER C N   1 
ATOM 3997 C CA  . SER E 1 95  ? 281.541 268.276 388.216 1.00 57.87  ? 95  SER C CA  1 
ATOM 3998 C C   . SER E 1 95  ? 282.875 268.230 388.941 1.00 57.87  ? 95  SER C C   1 
ATOM 3999 O O   . SER E 1 95  ? 283.076 268.923 389.939 1.00 57.87  ? 95  SER C O   1 
ATOM 4000 C CB  . SER E 1 95  ? 281.598 269.278 387.058 1.00 57.87  ? 95  SER C CB  1 
ATOM 4001 O OG  . SER E 1 95  ? 282.854 269.224 386.408 1.00 57.87  ? 95  SER C OG  1 
ATOM 4002 N N   . PHE E 1 96  ? 283.789 267.412 388.427 1.00 60.28  ? 96  PHE C N   1 
ATOM 4003 C CA  . PHE E 1 96  ? 285.068 267.198 389.084 1.00 60.28  ? 96  PHE C CA  1 
ATOM 4004 C C   . PHE E 1 96  ? 286.095 266.760 388.052 1.00 60.28  ? 96  PHE C C   1 
ATOM 4005 O O   . PHE E 1 96  ? 285.765 266.444 386.907 1.00 60.28  ? 96  PHE C O   1 
ATOM 4006 C CB  . PHE E 1 96  ? 284.955 266.157 390.201 1.00 60.28  ? 96  PHE C CB  1 
ATOM 4007 C CG  . PHE E 1 96  ? 284.223 266.648 391.409 1.00 60.28  ? 96  PHE C CG  1 
ATOM 4008 C CD1 . PHE E 1 96  ? 284.780 267.610 392.226 1.00 60.28  ? 96  PHE C CD1 1 
ATOM 4009 C CD2 . PHE E 1 96  ? 282.965 266.167 391.712 1.00 60.28  ? 96  PHE C CD2 1 
ATOM 4010 C CE1 . PHE E 1 96  ? 284.104 268.069 393.333 1.00 60.28  ? 96  PHE C CE1 1 
ATOM 4011 C CE2 . PHE E 1 96  ? 282.286 266.624 392.817 1.00 60.28  ? 96  PHE C CE2 1 
ATOM 4012 C CZ  . PHE E 1 96  ? 282.854 267.579 393.626 1.00 60.28  ? 96  PHE C CZ  1 
ATOM 4013 N N   . THR E 1 97  ? 287.353 266.748 388.475 1.00 74.00  ? 97  THR C N   1 
ATOM 4014 C CA  . THR E 1 97  ? 288.458 266.276 387.659 1.00 74.00  ? 97  THR C CA  1 
ATOM 4015 C C   . THR E 1 97  ? 289.067 265.050 388.325 1.00 74.00  ? 97  THR C C   1 
ATOM 4016 O O   . THR E 1 97  ? 289.071 264.932 389.553 1.00 74.00  ? 97  THR C O   1 
ATOM 4017 C CB  . THR E 1 97  ? 289.514 267.372 387.467 1.00 74.00  ? 97  THR C CB  1 
ATOM 4018 O OG1 . THR E 1 97  ? 288.885 268.550 386.951 1.00 74.00  ? 97  THR C OG1 1 
ATOM 4019 C CG2 . THR E 1 97  ? 290.587 266.928 386.484 1.00 74.00  ? 97  THR C CG2 1 
ATOM 4020 N N   . GLN E 1 98  ? 289.576 264.133 387.500 1.00 84.98  ? 98  GLN C N   1 
ATOM 4021 C CA  . GLN E 1 98  ? 290.036 262.844 388.008 1.00 84.98  ? 98  GLN C CA  1 
ATOM 4022 C C   . GLN E 1 98  ? 291.150 263.003 389.035 1.00 84.98  ? 98  GLN C C   1 
ATOM 4023 O O   . GLN E 1 98  ? 291.380 262.105 389.853 1.00 84.98  ? 98  GLN C O   1 
ATOM 4024 C CB  . GLN E 1 98  ? 290.491 261.969 386.843 1.00 84.98  ? 98  GLN C CB  1 
ATOM 4025 C CG  . GLN E 1 98  ? 291.551 262.612 385.975 1.00 84.98  ? 98  GLN C CG  1 
ATOM 4026 C CD  . GLN E 1 98  ? 291.779 261.853 384.687 1.00 84.98  ? 98  GLN C CD  1 
ATOM 4027 O OE1 . GLN E 1 98  ? 291.171 260.810 384.454 1.00 84.98  ? 98  GLN C OE1 1 
ATOM 4028 N NE2 . GLN E 1 98  ? 292.658 262.374 383.840 1.00 84.98  ? 98  GLN C NE2 1 
ATOM 4029 N N   . TYR E 1 99  ? 291.854 264.136 389.014 1.00 79.78  ? 99  TYR C N   1 
ATOM 4030 C CA  . TYR E 1 99  ? 292.909 264.367 389.993 1.00 79.78  ? 99  TYR C CA  1 
ATOM 4031 C C   . TYR E 1 99  ? 292.403 265.062 391.251 1.00 79.78  ? 99  TYR C C   1 
ATOM 4032 O O   . TYR E 1 99  ? 293.189 265.272 392.181 1.00 79.78  ? 99  TYR C O   1 
ATOM 4033 C CB  . TYR E 1 99  ? 294.037 265.188 389.372 1.00 79.78  ? 99  TYR C CB  1 
ATOM 4034 C CG  . TYR E 1 99  ? 294.894 264.411 388.404 1.00 79.78  ? 99  TYR C CG  1 
ATOM 4035 C CD1 . TYR E 1 99  ? 295.877 263.546 388.860 1.00 79.78  ? 99  TYR C CD1 1 
ATOM 4036 C CD2 . TYR E 1 99  ? 294.721 264.542 387.034 1.00 79.78  ? 99  TYR C CD2 1 
ATOM 4037 C CE1 . TYR E 1 99  ? 296.663 262.833 387.979 1.00 79.78  ? 99  TYR C CE1 1 
ATOM 4038 C CE2 . TYR E 1 99  ? 295.502 263.834 386.146 1.00 79.78  ? 99  TYR C CE2 1 
ATOM 4039 C CZ  . TYR E 1 99  ? 296.472 262.981 386.623 1.00 79.78  ? 99  TYR C CZ  1 
ATOM 4040 O OH  . TYR E 1 99  ? 297.252 262.274 385.740 1.00 79.78  ? 99  TYR C OH  1 
ATOM 4041 N N   . SER E 1 100 ? 291.125 265.428 391.303 1.00 75.41  ? 100 SER C N   1 
ATOM 4042 C CA  . SER E 1 100 ? 290.594 266.120 392.471 1.00 75.41  ? 100 SER C CA  1 
ATOM 4043 C C   . SER E 1 100 ? 290.590 265.200 393.683 1.00 75.41  ? 100 SER C C   1 
ATOM 4044 O O   . SER E 1 100 ? 290.171 264.043 393.600 1.00 75.41  ? 100 SER C O   1 
ATOM 4045 C CB  . SER E 1 100 ? 289.182 266.623 392.187 1.00 75.41  ? 100 SER C CB  1 
ATOM 4046 O OG  . SER E 1 100 ? 288.327 265.548 391.841 1.00 75.41  ? 100 SER C OG  1 
ATOM 4047 N N   . THR E 1 101 ? 291.045 265.724 394.817 1.00 77.19  ? 101 THR C N   1 
ATOM 4048 C CA  . THR E 1 101 ? 291.157 264.933 396.031 1.00 77.19  ? 101 THR C CA  1 
ATOM 4049 C C   . THR E 1 101 ? 289.797 264.793 396.713 1.00 77.19  ? 101 THR C C   1 
ATOM 4050 O O   . THR E 1 101 ? 288.752 265.156 396.167 1.00 77.19  ? 101 THR C O   1 
ATOM 4051 C CB  . THR E 1 101 ? 292.177 265.554 396.981 1.00 77.19  ? 101 THR C CB  1 
ATOM 4052 O OG1 . THR E 1 101 ? 292.381 264.682 398.099 1.00 77.19  ? 101 THR C OG1 1 
ATOM 4053 C CG2 . THR E 1 101 ? 291.689 266.904 397.480 1.00 77.19  ? 101 THR C CG2 1 
ATOM 4054 N N   . ASP E 1 102 ? 289.816 264.247 397.930 1.00 81.06  ? 102 ASP C N   1 
ATOM 4055 C CA  . ASP E 1 102 ? 288.576 264.021 398.663 1.00 81.06  ? 102 ASP C CA  1 
ATOM 4056 C C   . ASP E 1 102 ? 288.064 265.300 399.314 1.00 81.06  ? 102 ASP C C   1 
ATOM 4057 O O   . ASP E 1 102 ? 286.890 265.654 399.159 1.00 81.06  ? 102 ASP C O   1 
ATOM 4058 C CB  . ASP E 1 102 ? 288.786 262.936 399.717 1.00 81.06  ? 102 ASP C CB  1 
ATOM 4059 C CG  . ASP E 1 102 ? 287.503 262.555 400.422 1.00 81.06  ? 102 ASP C CG  1 
ATOM 4060 O OD1 . ASP E 1 102 ? 286.667 261.861 399.806 1.00 81.06  ? 102 ASP C OD1 1 
ATOM 4061 O OD2 . ASP E 1 102 ? 287.330 262.951 401.593 1.00 81.06  ? 102 ASP C OD2 1 
ATOM 4062 N N   . GLU E 1 103 ? 288.925 266.002 400.055 1.00 77.01  ? 103 GLU C N   1 
ATOM 4063 C CA  . GLU E 1 103 ? 288.470 267.167 400.806 1.00 77.01  ? 103 GLU C CA  1 
ATOM 4064 C C   . GLU E 1 103 ? 288.049 268.299 399.880 1.00 77.01  ? 103 GLU C C   1 
ATOM 4065 O O   . GLU E 1 103 ? 287.076 269.011 400.158 1.00 77.01  ? 103 GLU C O   1 
ATOM 4066 C CB  . GLU E 1 103 ? 289.565 267.631 401.766 1.00 77.01  ? 103 GLU C CB  1 
ATOM 4067 C CG  . GLU E 1 103 ? 289.790 266.708 402.962 1.00 77.01  ? 103 GLU C CG  1 
ATOM 4068 C CD  . GLU E 1 103 ? 288.535 265.971 403.410 1.00 77.01  ? 103 GLU C CD  1 
ATOM 4069 O OE1 . GLU E 1 103 ? 287.490 266.624 403.628 1.00 77.01  ? 103 GLU C OE1 1 
ATOM 4070 O OE2 . GLU E 1 103 ? 288.592 264.730 403.541 1.00 77.01  ? 103 GLU C OE2 1 
ATOM 4071 N N   . GLU E 1 104 ? 288.770 268.488 398.774 1.00 76.34  ? 104 GLU C N   1 
ATOM 4072 C CA  . GLU E 1 104 ? 288.365 269.501 397.808 1.00 76.34  ? 104 GLU C CA  1 
ATOM 4073 C C   . GLU E 1 104 ? 287.003 269.166 397.217 1.00 76.34  ? 104 GLU C C   1 
ATOM 4074 O O   . GLU E 1 104 ? 286.197 270.062 396.946 1.00 76.34  ? 104 GLU C O   1 
ATOM 4075 C CB  . GLU E 1 104 ? 289.424 269.633 396.713 1.00 76.34  ? 104 GLU C CB  1 
ATOM 4076 C CG  . GLU E 1 104 ? 289.231 270.818 395.778 1.00 76.34  ? 104 GLU C CG  1 
ATOM 4077 C CD  . GLU E 1 104 ? 288.259 270.530 394.656 1.00 76.34  ? 104 GLU C CD  1 
ATOM 4078 O OE1 . GLU E 1 104 ? 288.147 269.353 394.258 1.00 76.34  ? 104 GLU C OE1 1 
ATOM 4079 O OE2 . GLU E 1 104 ? 287.607 271.478 394.171 1.00 76.34  ? 104 GLU C OE2 1 
ATOM 4080 N N   . ARG E 1 105 ? 286.729 267.876 397.012 1.00 69.16  ? 105 ARG C N   1 
ATOM 4081 C CA  . ARG E 1 105 ? 285.403 267.465 396.566 1.00 69.16  ? 105 ARG C CA  1 
ATOM 4082 C C   . ARG E 1 105 ? 284.349 267.777 397.618 1.00 69.16  ? 105 ARG C C   1 
ATOM 4083 O O   . ARG E 1 105 ? 283.275 268.298 397.298 1.00 69.16  ? 105 ARG C O   1 
ATOM 4084 C CB  . ARG E 1 105 ? 285.404 265.972 396.235 1.00 69.16  ? 105 ARG C CB  1 
ATOM 4085 C CG  . ARG E 1 105 ? 284.036 265.403 395.889 1.00 69.16  ? 105 ARG C CG  1 
ATOM 4086 C CD  . ARG E 1 105 ? 283.505 264.478 396.978 1.00 69.16  ? 105 ARG C CD  1 
ATOM 4087 N NE  . ARG E 1 105 ? 282.113 264.108 396.746 1.00 69.16  ? 105 ARG C NE  1 
ATOM 4088 C CZ  . ARG E 1 105 ? 281.463 263.170 397.420 1.00 69.16  ? 105 ARG C CZ  1 
ATOM 4089 N NH1 . ARG E 1 105 ? 282.050 262.480 398.385 1.00 69.16  ? 105 ARG C NH1 1 
ATOM 4090 N NH2 . ARG E 1 105 ? 280.194 262.915 397.116 1.00 69.16  ? 105 ARG C NH2 1 
ATOM 4091 N N   . ALA E 1 106 ? 284.641 267.471 398.883 1.00 69.05  ? 106 ALA C N   1 
ATOM 4092 C CA  . ALA E 1 106 ? 283.647 267.654 399.935 1.00 69.05  ? 106 ALA C CA  1 
ATOM 4093 C C   . ALA E 1 106 ? 283.385 269.126 400.216 1.00 69.05  ? 106 ALA C C   1 
ATOM 4094 O O   . ALA E 1 106 ? 282.326 269.476 400.751 1.00 69.05  ? 106 ALA C O   1 
ATOM 4095 C CB  . ALA E 1 106 ? 284.095 266.945 401.212 1.00 69.05  ? 106 ALA C CB  1 
ATOM 4096 N N   . PHE E 1 107 ? 284.340 269.996 399.885 1.00 68.15  ? 107 PHE C N   1 
ATOM 4097 C CA  . PHE E 1 107 ? 284.145 271.422 400.129 1.00 68.15  ? 107 PHE C CA  1 
ATOM 4098 C C   . PHE E 1 107 ? 282.965 271.965 399.335 1.00 68.15  ? 107 PHE C C   1 
ATOM 4099 O O   . PHE E 1 107 ? 282.166 272.753 399.858 1.00 68.15  ? 107 PHE C O   1 
ATOM 4100 C CB  . PHE E 1 107 ? 285.415 272.195 399.787 1.00 68.15  ? 107 PHE C CB  1 
ATOM 4101 C CG  . PHE E 1 107 ? 285.520 273.515 400.487 1.00 68.15  ? 107 PHE C CG  1 
ATOM 4102 C CD1 . PHE E 1 107 ? 285.507 273.582 401.868 1.00 68.15  ? 107 PHE C CD1 1 
ATOM 4103 C CD2 . PHE E 1 107 ? 285.621 274.689 399.765 1.00 68.15  ? 107 PHE C CD2 1 
ATOM 4104 C CE1 . PHE E 1 107 ? 285.601 274.794 402.515 1.00 68.15  ? 107 PHE C CE1 1 
ATOM 4105 C CE2 . PHE E 1 107 ? 285.715 275.904 400.406 1.00 68.15  ? 107 PHE C CE2 1 
ATOM 4106 C CZ  . PHE E 1 107 ? 285.704 275.957 401.783 1.00 68.15  ? 107 PHE C CZ  1 
ATOM 4107 N N   . VAL E 1 108 ? 282.840 271.561 398.069 1.00 62.18  ? 108 VAL C N   1 
ATOM 4108 C CA  . VAL E 1 108 ? 281.730 272.028 397.245 1.00 62.18  ? 108 VAL C CA  1 
ATOM 4109 C C   . VAL E 1 108 ? 280.403 271.600 397.852 1.00 62.18  ? 108 VAL C C   1 
ATOM 4110 O O   . VAL E 1 108 ? 279.470 272.403 397.978 1.00 62.18  ? 108 VAL C O   1 
ATOM 4111 C CB  . VAL E 1 108 ? 281.881 271.512 395.804 1.00 62.18  ? 108 VAL C CB  1 
ATOM 4112 C CG1 . VAL E 1 108 ? 280.579 271.673 395.045 1.00 62.18  ? 108 VAL C CG1 1 
ATOM 4113 C CG2 . VAL E 1 108 ? 283.006 272.239 395.098 1.00 62.18  ? 108 VAL C CG2 1 
ATOM 4114 N N   . ARG E 1 109 ? 280.302 270.330 398.246 1.00 64.00  ? 109 ARG C N   1 
ATOM 4115 C CA  . ARG E 1 109 ? 279.061 269.833 398.828 1.00 64.00  ? 109 ARG C CA  1 
ATOM 4116 C C   . ARG E 1 109 ? 278.725 270.572 400.114 1.00 64.00  ? 109 ARG C C   1 
ATOM 4117 O O   . ARG E 1 109 ? 277.575 270.968 400.331 1.00 64.00  ? 109 ARG C O   1 
ATOM 4118 C CB  . ARG E 1 109 ? 279.166 268.331 399.087 1.00 64.00  ? 109 ARG C CB  1 
ATOM 4119 C CG  . ARG E 1 109 ? 278.107 267.804 400.032 1.00 64.00  ? 109 ARG C CG  1 
ATOM 4120 C CD  . ARG E 1 109 ? 278.390 266.372 400.428 1.00 64.00  ? 109 ARG C CD  1 
ATOM 4121 N NE  . ARG E 1 109 ? 279.246 266.299 401.605 1.00 64.00  ? 109 ARG C NE  1 
ATOM 4122 C CZ  . ARG E 1 109 ? 278.800 266.279 402.853 1.00 64.00  ? 109 ARG C CZ  1 
ATOM 4123 N NH1 . ARG E 1 109 ? 277.507 266.331 403.125 1.00 64.00  ? 109 ARG C NH1 1 
ATOM 4124 N NH2 . ARG E 1 109 ? 279.673 266.206 403.853 1.00 64.00  ? 109 ARG C NH2 1 
ATOM 4125 N N   . THR E 1 110 ? 279.718 270.770 400.983 1.00 70.54  ? 110 THR C N   1 
ATOM 4126 C CA  . THR E 1 110 ? 279.451 271.449 402.246 1.00 70.54  ? 110 THR C CA  1 
ATOM 4127 C C   . THR E 1 110 ? 278.997 272.883 402.019 1.00 70.54  ? 110 THR C C   1 
ATOM 4128 O O   . THR E 1 110 ? 278.039 273.343 402.653 1.00 70.54  ? 110 THR C O   1 
ATOM 4129 C CB  . THR E 1 110 ? 280.687 271.420 403.144 1.00 70.54  ? 110 THR C CB  1 
ATOM 4130 O OG1 . THR E 1 110 ? 281.846 271.772 402.379 1.00 70.54  ? 110 THR C OG1 1 
ATOM 4131 C CG2 . THR E 1 110 ? 280.873 270.040 403.745 1.00 70.54  ? 110 THR C CG2 1 
ATOM 4132 N N   . GLU E 1 111 ? 279.665 273.610 401.119 1.00 71.31  ? 111 GLU C N   1 
ATOM 4133 C CA  . GLU E 1 111 ? 279.282 275.000 400.900 1.00 71.31  ? 111 GLU C CA  1 
ATOM 4134 C C   . GLU E 1 111 ? 277.899 275.084 400.268 1.00 71.31  ? 111 GLU C C   1 
ATOM 4135 O O   . GLU E 1 111 ? 277.106 275.965 400.611 1.00 71.31  ? 111 GLU C O   1 
ATOM 4136 C CB  . GLU E 1 111 ? 280.320 275.738 400.049 1.00 71.31  ? 111 GLU C CB  1 
ATOM 4137 C CG  . GLU E 1 111 ? 280.197 275.550 398.547 1.00 71.31  ? 111 GLU C CG  1 
ATOM 4138 C CD  . GLU E 1 111 ? 280.980 276.587 397.767 1.00 71.31  ? 111 GLU C CD  1 
ATOM 4139 O OE1 . GLU E 1 111 ? 281.649 277.429 398.402 1.00 71.31  ? 111 GLU C OE1 1 
ATOM 4140 O OE2 . GLU E 1 111 ? 280.918 276.569 396.520 1.00 71.31  ? 111 GLU C OE2 1 
ATOM 4141 N N   . LEU E 1 112 ? 277.575 274.157 399.362 1.00 61.96  ? 112 LEU C N   1 
ATOM 4142 C CA  . LEU E 1 112 ? 276.255 274.192 398.743 1.00 61.96  ? 112 LEU C CA  1 
ATOM 4143 C C   . LEU E 1 112 ? 275.171 273.835 399.750 1.00 61.96  ? 112 LEU C C   1 
ATOM 4144 O O   . LEU E 1 112 ? 274.064 274.382 399.702 1.00 61.96  ? 112 LEU C O   1 
ATOM 4145 C CB  . LEU E 1 112 ? 276.208 273.250 397.543 1.00 61.96  ? 112 LEU C CB  1 
ATOM 4146 C CG  . LEU E 1 112 ? 274.942 273.329 396.691 1.00 61.96  ? 112 LEU C CG  1 
ATOM 4147 C CD1 . LEU E 1 112 ? 274.524 274.769 396.494 1.00 61.96  ? 112 LEU C CD1 1 
ATOM 4148 C CD2 . LEU E 1 112 ? 275.164 272.658 395.353 1.00 61.96  ? 112 LEU C CD2 1 
ATOM 4149 N N   . ALA E 1 113 ? 275.471 272.921 400.673 1.00 65.26  ? 113 ALA C N   1 
ATOM 4150 C CA  . ALA E 1 113 ? 274.491 272.554 401.688 1.00 65.26  ? 113 ALA C CA  1 
ATOM 4151 C C   . ALA E 1 113 ? 274.265 273.688 402.675 1.00 65.26  ? 113 ALA C C   1 
ATOM 4152 O O   . ALA E 1 113 ? 273.129 273.939 403.093 1.00 65.26  ? 113 ALA C O   1 
ATOM 4153 C CB  . ALA E 1 113 ? 274.938 271.290 402.420 1.00 65.26  ? 113 ALA C CB  1 
ATOM 4154 N N   . ALA E 1 114 ? 275.330 274.383 403.065 1.00 63.28  ? 114 ALA C N   1 
ATOM 4155 C CA  . ALA E 1 114 ? 275.223 275.452 404.047 1.00 63.28  ? 114 ALA C CA  1 
ATOM 4156 C C   . ALA E 1 114 ? 274.799 276.783 403.443 1.00 63.28  ? 114 ALA C C   1 
ATOM 4157 O O   . ALA E 1 114 ? 274.396 277.681 404.187 1.00 63.28  ? 114 ALA C O   1 
ATOM 4158 C CB  . ALA E 1 114 ? 276.552 275.626 404.786 1.00 63.28  ? 114 ALA C CB  1 
ATOM 4159 N N   . LEU E 1 115 ? 274.879 276.937 402.121 1.00 61.58  ? 115 LEU C N   1 
ATOM 4160 C CA  . LEU E 1 115 ? 274.516 278.208 401.509 1.00 61.58  ? 115 LEU C CA  1 
ATOM 4161 C C   . LEU E 1 115 ? 273.016 278.279 401.252 1.00 61.58  ? 115 LEU C C   1 
ATOM 4162 O O   . LEU E 1 115 ? 272.416 279.358 401.313 1.00 61.58  ? 115 LEU C O   1 
ATOM 4163 C CB  . LEU E 1 115 ? 275.309 278.403 400.218 1.00 61.58  ? 115 LEU C CB  1 
ATOM 4164 C CG  . LEU E 1 115 ? 275.198 279.757 399.524 1.00 61.58  ? 115 LEU C CG  1 
ATOM 4165 C CD1 . LEU E 1 115 ? 275.754 280.846 400.416 1.00 61.58  ? 115 LEU C CD1 1 
ATOM 4166 C CD2 . LEU E 1 115 ? 275.923 279.735 398.191 1.00 61.58  ? 115 LEU C CD2 1 
ATOM 4167 N N   . LEU E 1 116 ? 272.392 277.136 400.960 1.00 59.88  ? 116 LEU C N   1 
ATOM 4168 C CA  . LEU E 1 116 ? 270.942 277.101 400.814 1.00 59.88  ? 116 LEU C CA  1 
ATOM 4169 C C   . LEU E 1 116 ? 270.224 277.411 402.118 1.00 59.88  ? 116 LEU C C   1 
ATOM 4170 O O   . LEU E 1 116 ? 269.043 277.772 402.094 1.00 59.88  ? 116 LEU C O   1 
ATOM 4171 C CB  . LEU E 1 116 ? 270.496 275.738 400.287 1.00 59.88  ? 116 LEU C CB  1 
ATOM 4172 C CG  . LEU E 1 116 ? 271.044 275.336 398.920 1.00 59.88  ? 116 LEU C CG  1 
ATOM 4173 C CD1 . LEU E 1 116 ? 270.442 274.021 398.473 1.00 59.88  ? 116 LEU C CD1 1 
ATOM 4174 C CD2 . LEU E 1 116 ? 270.750 276.420 397.907 1.00 59.88  ? 116 LEU C CD2 1 
ATOM 4175 N N   . ALA E 1 117 ? 270.898 277.267 403.255 1.00 61.81  ? 117 ALA C N   1 
ATOM 4176 C CA  . ALA E 1 117 ? 270.332 277.671 404.533 1.00 61.81  ? 117 ALA C CA  1 
ATOM 4177 C C   . ALA E 1 117 ? 270.651 279.116 404.884 1.00 61.81  ? 117 ALA C C   1 
ATOM 4178 O O   . ALA E 1 117 ? 270.105 279.635 405.863 1.00 61.81  ? 117 ALA C O   1 
ATOM 4179 C CB  . ALA E 1 117 ? 270.830 276.751 405.651 1.00 61.81  ? 117 ALA C CB  1 
ATOM 4180 N N   . SER E 1 118 ? 271.513 279.770 404.115 1.00 63.28  ? 118 SER C N   1 
ATOM 4181 C CA  . SER E 1 118 ? 271.812 281.176 404.314 1.00 63.28  ? 118 SER C CA  1 
ATOM 4182 C C   . SER E 1 118 ? 270.632 282.029 403.864 1.00 63.28  ? 118 SER C C   1 
ATOM 4183 O O   . SER E 1 118 ? 269.874 281.634 402.976 1.00 63.28  ? 118 SER C O   1 
ATOM 4184 C CB  . SER E 1 118 ? 273.068 281.551 403.533 1.00 63.28  ? 118 SER C CB  1 
ATOM 4185 O OG  . SER E 1 118 ? 273.385 282.923 403.668 1.00 63.28  ? 118 SER C OG  1 
ATOM 4186 N N   . PRO E 1 119 ? 270.445 283.205 404.470 1.00 66.04  ? 119 PRO C N   1 
ATOM 4187 C CA  . PRO E 1 119 ? 269.337 284.068 404.030 1.00 66.04  ? 119 PRO C CA  1 
ATOM 4188 C C   . PRO E 1 119 ? 269.429 284.468 402.570 1.00 66.04  ? 119 PRO C C   1 
ATOM 4189 O O   . PRO E 1 119 ? 268.394 284.683 401.926 1.00 66.04  ? 119 PRO C O   1 
ATOM 4190 C CB  . PRO E 1 119 ? 269.444 285.279 404.968 1.00 66.04  ? 119 PRO C CB  1 
ATOM 4191 C CG  . PRO E 1 119 ? 270.844 285.254 405.471 1.00 66.04  ? 119 PRO C CG  1 
ATOM 4192 C CD  . PRO E 1 119 ? 271.188 283.803 405.591 1.00 66.04  ? 119 PRO C CD  1 
ATOM 4193 N N   . LEU E 1 120 ? 270.644 284.538 402.021 1.00 63.06  ? 120 LEU C N   1 
ATOM 4194 C CA  . LEU E 1 120 ? 270.818 285.041 400.662 1.00 63.06  ? 120 LEU C CA  1 
ATOM 4195 C C   . LEU E 1 120 ? 270.071 284.191 399.643 1.00 63.06  ? 120 LEU C C   1 
ATOM 4196 O O   . LEU E 1 120 ? 269.406 284.729 398.750 1.00 63.06  ? 120 LEU C O   1 
ATOM 4197 C CB  . LEU E 1 120 ? 272.303 285.107 400.314 1.00 63.06  ? 120 LEU C CB  1 
ATOM 4198 C CG  . LEU E 1 120 ? 272.606 285.546 398.882 1.00 63.06  ? 120 LEU C CG  1 
ATOM 4199 C CD1 . LEU E 1 120 ? 272.026 286.924 398.621 1.00 63.06  ? 120 LEU C CD1 1 
ATOM 4200 C CD2 . LEU E 1 120 ? 274.102 285.536 398.626 1.00 63.06  ? 120 LEU C CD2 1 
ATOM 4201 N N   . LEU E 1 121 ? 270.163 282.863 399.751 1.00 64.37  ? 121 LEU C N   1 
ATOM 4202 C CA  . LEU E 1 121 ? 269.462 282.029 398.780 1.00 64.37  ? 121 LEU C CA  1 
ATOM 4203 C C   . LEU E 1 121 ? 268.070 281.644 399.254 1.00 64.37  ? 121 LEU C C   1 
ATOM 4204 O O   . LEU E 1 121 ? 267.190 281.388 398.428 1.00 64.37  ? 121 LEU C O   1 
ATOM 4205 C CB  . LEU E 1 121 ? 270.265 280.778 398.438 1.00 64.37  ? 121 LEU C CB  1 
ATOM 4206 C CG  . LEU E 1 121 ? 271.575 281.018 397.701 1.00 64.37  ? 121 LEU C CG  1 
ATOM 4207 C CD1 . LEU E 1 121 ? 272.322 279.713 397.547 1.00 64.37  ? 121 LEU C CD1 1 
ATOM 4208 C CD2 . LEU E 1 121 ? 271.296 281.647 396.349 1.00 64.37  ? 121 LEU C CD2 1 
ATOM 4209 N N   . ILE E 1 122 ? 267.834 281.596 400.566 1.00 64.74  ? 122 ILE C N   1 
ATOM 4210 C CA  . ILE E 1 122 ? 266.479 281.294 401.016 1.00 64.74  ? 122 ILE C CA  1 
ATOM 4211 C C   . ILE E 1 122 ? 265.532 282.403 400.575 1.00 64.74  ? 122 ILE C C   1 
ATOM 4212 O O   . ILE E 1 122 ? 264.391 282.143 400.173 1.00 64.74  ? 122 ILE C O   1 
ATOM 4213 C CB  . ILE E 1 122 ? 266.433 281.049 402.538 1.00 64.74  ? 122 ILE C CB  1 
ATOM 4214 C CG1 . ILE E 1 122 ? 265.206 280.208 402.897 1.00 64.74  ? 122 ILE C CG1 1 
ATOM 4215 C CG2 . ILE E 1 122 ? 266.374 282.345 403.313 1.00 64.74  ? 122 ILE C CG2 1 
ATOM 4216 C CD1 . ILE E 1 122 ? 265.263 278.783 402.382 1.00 64.74  ? 122 ILE C CD1 1 
ATOM 4217 N N   . ASP E 1 123 ? 266.011 283.649 400.579 1.00 67.77  ? 123 ASP C N   1 
ATOM 4218 C CA  . ASP E 1 123 ? 265.218 284.746 400.048 1.00 67.77  ? 123 ASP C CA  1 
ATOM 4219 C C   . ASP E 1 123 ? 265.141 284.728 398.528 1.00 67.77  ? 123 ASP C C   1 
ATOM 4220 O O   . ASP E 1 123 ? 264.069 284.999 397.981 1.00 67.77  ? 123 ASP C O   1 
ATOM 4221 C CB  . ASP E 1 123 ? 265.791 286.078 400.532 1.00 67.77  ? 123 ASP C CB  1 
ATOM 4222 C CG  . ASP E 1 123 ? 264.972 287.266 400.075 1.00 67.77  ? 123 ASP C CG  1 
ATOM 4223 O OD1 . ASP E 1 123 ? 265.157 287.711 398.924 1.00 67.77  ? 123 ASP C OD1 1 
ATOM 4224 O OD2 . ASP E 1 123 ? 264.137 287.753 400.865 1.00 67.77  ? 123 ASP C OD2 1 
ATOM 4225 N N   . ALA E 1 124 ? 266.232 284.400 397.838 1.00 65.84  ? 124 ALA C N   1 
ATOM 4226 C CA  . ALA E 1 124 ? 266.246 284.378 396.382 1.00 65.84  ? 124 ALA C CA  1 
ATOM 4227 C C   . ALA E 1 124 ? 265.480 283.203 395.789 1.00 65.84  ? 124 ALA C C   1 
ATOM 4228 O O   . ALA E 1 124 ? 265.195 283.214 394.587 1.00 65.84  ? 124 ALA C O   1 
ATOM 4229 C CB  . ALA E 1 124 ? 267.687 284.348 395.868 1.00 65.84  ? 124 ALA C CB  1 
ATOM 4230 N N   . ILE E 1 125 ? 265.155 282.194 396.589 1.00 62.25  ? 125 ILE C N   1 
ATOM 4231 C CA  . ILE E 1 125 ? 264.388 281.054 396.109 1.00 62.25  ? 125 ILE C CA  1 
ATOM 4232 C C   . ILE E 1 125 ? 263.018 280.949 396.760 1.00 62.25  ? 125 ILE C C   1 
ATOM 4233 O O   . ILE E 1 125 ? 262.195 280.137 396.308 1.00 62.25  ? 125 ILE C O   1 
ATOM 4234 C CB  . ILE E 1 125 ? 265.173 279.740 396.308 1.00 62.25  ? 125 ILE C CB  1 
ATOM 4235 C CG1 . ILE E 1 125 ? 264.762 278.698 395.268 1.00 62.25  ? 125 ILE C CG1 1 
ATOM 4236 C CG2 . ILE E 1 125 ? 264.944 279.190 397.704 1.00 62.25  ? 125 ILE C CG2 1 
ATOM 4237 C CD1 . ILE E 1 125 ? 265.730 277.538 395.157 1.00 62.25  ? 125 ILE C CD1 1 
ATOM 4238 N N   . ASP E 1 126 ? 262.727 281.735 397.797 1.00 74.03  ? 126 ASP C N   1 
ATOM 4239 C CA  . ASP E 1 126 ? 261.402 281.690 398.403 1.00 74.03  ? 126 ASP C CA  1 
ATOM 4240 C C   . ASP E 1 126 ? 260.422 282.585 397.653 1.00 74.03  ? 126 ASP C C   1 
ATOM 4241 O O   . ASP E 1 126 ? 259.295 282.173 397.357 1.00 74.03  ? 126 ASP C O   1 
ATOM 4242 C CB  . ASP E 1 126 ? 261.490 282.094 399.873 1.00 74.03  ? 126 ASP C CB  1 
ATOM 4243 C CG  . ASP E 1 126 ? 260.346 281.546 400.696 1.00 74.03  ? 126 ASP C CG  1 
ATOM 4244 O OD1 . ASP E 1 126 ? 259.199 281.553 400.203 1.00 74.03  ? 126 ASP C OD1 1 
ATOM 4245 O OD2 . ASP E 1 126 ? 260.593 281.108 401.838 1.00 74.03  ? 126 ASP C OD2 1 
ATOM 4246 N N   . GLN E 1 127 ? 260.831 283.817 397.334 1.00 71.30  ? 127 GLN C N   1 
ATOM 4247 C CA  . GLN E 1 127 ? 259.933 284.777 396.701 1.00 71.30  ? 127 GLN C CA  1 
ATOM 4248 C C   . GLN E 1 127 ? 260.390 285.173 395.301 1.00 71.30  ? 127 GLN C C   1 
ATOM 4249 O O   . GLN E 1 127 ? 259.858 286.133 394.736 1.00 71.30  ? 127 GLN C O   1 
ATOM 4250 C CB  . GLN E 1 127 ? 259.776 286.024 397.572 1.00 71.30  ? 127 GLN C CB  1 
ATOM 4251 C CG  . GLN E 1 127 ? 258.960 285.792 398.827 1.00 71.30  ? 127 GLN C CG  1 
ATOM 4252 C CD  . GLN E 1 127 ? 259.792 285.889 400.083 1.00 71.30  ? 127 GLN C CD  1 
ATOM 4253 O OE1 . GLN E 1 127 ? 260.776 285.170 400.244 1.00 71.30  ? 127 GLN C OE1 1 
ATOM 4254 N NE2 . GLN E 1 127 ? 259.402 286.781 400.985 1.00 71.30  ? 127 GLN C NE2 1 
ATOM 4255 N N   . LEU E 1 128 ? 261.359 284.456 394.733 1.00 73.25  ? 128 LEU C N   1 
ATOM 4256 C CA  . LEU E 1 128 ? 261.794 284.666 393.351 1.00 73.25  ? 128 LEU C CA  1 
ATOM 4257 C C   . LEU E 1 128 ? 262.205 286.114 393.097 1.00 73.25  ? 128 LEU C C   1 
ATOM 4258 O O   . LEU E 1 128 ? 261.935 286.680 392.037 1.00 73.25  ? 128 LEU C O   1 
ATOM 4259 C CB  . LEU E 1 128 ? 260.711 284.240 392.359 1.00 73.25  ? 128 LEU C CB  1 
ATOM 4260 C CG  . LEU E 1 128 ? 260.385 282.756 392.195 1.00 73.25  ? 128 LEU C CG  1 
ATOM 4261 C CD1 . LEU E 1 128 ? 259.492 282.250 393.319 1.00 73.25  ? 128 LEU C CD1 1 
ATOM 4262 C CD2 . LEU E 1 128 ? 259.741 282.513 390.837 1.00 73.25  ? 128 LEU C CD2 1 
ATOM 4263 N N   . ASN E 1 129 ? 262.862 286.724 394.077 1.00 75.99  ? 129 ASN C N   1 
ATOM 4264 C CA  . ASN E 1 129 ? 263.376 288.079 393.911 1.00 75.99  ? 129 ASN C CA  1 
ATOM 4265 C C   . ASN E 1 129 ? 264.880 288.063 393.674 1.00 75.99  ? 129 ASN C C   1 
ATOM 4266 O O   . ASN E 1 129 ? 265.642 287.650 394.561 1.00 75.99  ? 129 ASN C O   1 
ATOM 4267 C CB  . ASN E 1 129 ? 263.022 288.951 395.119 1.00 75.99  ? 129 ASN C CB  1 
ATOM 4268 C CG  . ASN E 1 129 ? 263.424 288.329 396.440 1.00 75.99  ? 129 ASN C CG  1 
ATOM 4269 O OD1 . ASN E 1 129 ? 263.997 287.245 396.485 1.00 75.99  ? 129 ASN C OD1 1 
ATOM 4270 N ND2 . ASN E 1 129 ? 263.129 289.025 397.530 1.00 75.99  ? 129 ASN C ND2 1 
ATOM 4271 N N   . PRO E 1 130 ? 265.354 288.483 392.504 1.00 80.06  ? 130 PRO C N   1 
ATOM 4272 C CA  . PRO E 1 130 ? 266.793 288.421 392.234 1.00 80.06  ? 130 PRO C CA  1 
ATOM 4273 C C   . PRO E 1 130 ? 267.566 289.361 393.143 1.00 80.06  ? 130 PRO C C   1 
ATOM 4274 O O   . PRO E 1 130 ? 267.064 290.407 393.558 1.00 80.06  ? 130 PRO C O   1 
ATOM 4275 C CB  . PRO E 1 130 ? 266.893 288.849 390.768 1.00 80.06  ? 130 PRO C CB  1 
ATOM 4276 C CG  . PRO E 1 130 ? 265.735 289.760 390.583 1.00 80.06  ? 130 PRO C CG  1 
ATOM 4277 C CD  . PRO E 1 130 ? 264.628 289.216 391.454 1.00 80.06  ? 130 PRO C CD  1 
ATOM 4278 N N   . ALA E 1 131 ? 268.796 288.970 393.458 1.00 84.21  ? 131 ALA C N   1 
ATOM 4279 C CA  . ALA E 1 131 ? 269.648 289.806 394.288 1.00 84.21  ? 131 ALA C CA  1 
ATOM 4280 C C   . ALA E 1 131 ? 270.068 291.052 393.521 1.00 84.21  ? 131 ALA C C   1 
ATOM 4281 O O   . ALA E 1 131 ? 270.283 291.012 392.306 1.00 84.21  ? 131 ALA C O   1 
ATOM 4282 C CB  . ALA E 1 131 ? 270.877 289.027 394.749 1.00 84.21  ? 131 ALA C CB  1 
ATOM 4283 N N   . TYR E 1 132 ? 270.180 292.163 394.238 1.00 97.50  ? 132 TYR C N   1 
ATOM 4284 C CA  . TYR E 1 132 ? 270.529 293.439 393.631 1.00 97.50  ? 132 TYR C CA  1 
ATOM 4285 C C   . TYR E 1 132 ? 271.931 293.884 394.026 1.00 97.50  ? 132 TYR C C   1 
ATOM 4286 O O   . TYR E 1 132 ? 272.311 295.032 393.803 1.00 97.50  ? 132 TYR C O   1 
ATOM 4287 C CB  . TYR E 1 132 ? 269.503 294.504 394.022 1.00 97.50  ? 132 TYR C CB  1 
ATOM 4288 C CG  . TYR E 1 132 ? 269.455 294.803 395.504 1.00 97.50  ? 132 TYR C CG  1 
ATOM 4289 C CD1 . TYR E 1 132 ? 268.612 294.090 396.346 1.00 97.50  ? 132 TYR C CD1 1 
ATOM 4290 C CD2 . TYR E 1 132 ? 270.243 295.801 396.059 1.00 97.50  ? 132 TYR C CD2 1 
ATOM 4291 C CE1 . TYR E 1 132 ? 268.561 294.359 397.698 1.00 97.50  ? 132 TYR C CE1 1 
ATOM 4292 C CE2 . TYR E 1 132 ? 270.199 296.076 397.410 1.00 97.50  ? 132 TYR C CE2 1 
ATOM 4293 C CZ  . TYR E 1 132 ? 269.357 295.353 398.225 1.00 97.50  ? 132 TYR C CZ  1 
ATOM 4294 O OH  . TYR E 1 132 ? 269.311 295.626 399.571 1.00 97.50  ? 132 TYR C OH  1 
# 
