data_8W5F
# 
_entry.id   8W5F 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8W5F         pdb_00008w5f 10.2210/pdb8w5f/pdb 
WWPDB D_1300040591 ?            ?                   
EMDB  EMD-37290    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-02-26 ? 
2 'EM metadata'     1 0 2025-02-26 ? 
3 'Half map'        1 0 2025-02-26 1 
4 'Half map'        1 0 2025-02-26 2 
5 Image             1 0 2025-02-26 ? 
6 'Primary map'     1 0 2025-02-26 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Half map'        repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 Image             repository 'Initial release' ? ? 
6 6 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8W5F 
_pdbx_database_status.recvd_initial_deposition_date   2023-08-26 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure of Qb-Ab6' 
_pdbx_database_related.db_id          EMD-37290 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              zhup@ibp.ac.cn 
_pdbx_contact_author.name_first         Ping 
_pdbx_contact_author.name_last          Zhu 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-2648-3170 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Bao, K.Y.' 1 ? 
'Li, R.H.'  2 ? 
'Hua, Z.L.' 3 ? 
'Hou, B.D.' 4 ? 
'Zhu, P.'   5 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Cell Rep' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2211-1247 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            44 
_citation.language                  ? 
_citation.page_first                115334 
_citation.page_last                 115334 
_citation.title                     
'Competition propels, rather than limits, the success of low-affinity B cells in the germinal center response.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.celrep.2025.115334 
_citation.pdbx_database_id_PubMed   39955776 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Li, R.'  1 ? 
primary 'Bao, K.' 2 ? 
primary 'Liu, C.' 3 ? 
primary 'Ma, X.'  4 ? 
primary 'Hua, Z.' 5 ? 
primary 'Zhu, P.' 6 ? 
primary 'Hou, B.' 7 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'Light chain of Ab6'      12014.307 1 ? ? ? ? 
2 polymer man 'Heavy chain of Ab6'      14077.556 1 ? ? ? ? 
3 polymer man 'Minor capsid protein A1' 14268.071 2 ? ? ? ? 
# 
_entity_name_com.entity_id   3 
_entity_name_com.name        'Qb coat protein' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;VHSDIQMTQSPASLSVSVGETVTLTCRASENIYSNLAWYHQKQGISPQLLVYAAAKLADGVPSRFSGSGSGTQYSFKINS
LQSEDFGSYYCQHFWGTPWTFGGGTKLEIK
;
;VHSDIQMTQSPASLSVSVGETVTLTCRASENIYSNLAWYHQKQGISPQLLVYAAAKLADGVPSRFSGSGSGTQYSFKINS
LQSEDFGSYYCQHFWGTPWTFGGGTKLEIK
;
L   ? 
2 'polypeptide(L)' no no 
;VHSQVQLQQPGTELVKPGASVKLSCKASGYTFTSYSVHWVKQRPGQGLEWIGSINPNNDVAYFNEKFKTKATLTVDRSSS
TAYMQLSSLTFEDSAVYYCARGGIHYTYDGYYFDYWGQGTTLTVSS
;
;VHSQVQLQQPGTELVKPGASVKLSCKASGYTFTSYSVHWVKQRPGQGLEWIGSINPNNDVAYFNEKFKTKATLTVDRSSS
TAYMQLSSLTFEDSAVYYCARGGIHYTYDGYYFDYWGQGTTLTVSS
;
H   ? 
3 'polypeptide(L)' no no 
;MAKLETVTLGNIGKDGKQTLVLNPRGVNPTNGVASLSQAGAVPALEKRVTVSVSQPSRNRKNYKVQVKIQNPTACTANGS
CDPSVTRQAYADVTFSFTQYSTDEERAFVRTELAALLASPLLIDAIDQLNPAY
;
;MAKLETVTLGNIGKDGKQTLVLNPRGVNPTNGVASLSQAGAVPALEKRVTVSVSQPSRNRKNYKVQVKIQNPTACTANGS
CDPSVTRQAYADVTFSFTQYSTDEERAFVRTELAALLASPLLIDAIDQLNPAY
;
c,C ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   VAL n 
1 2   HIS n 
1 3   SER n 
1 4   ASP n 
1 5   ILE n 
1 6   GLN n 
1 7   MET n 
1 8   THR n 
1 9   GLN n 
1 10  SER n 
1 11  PRO n 
1 12  ALA n 
1 13  SER n 
1 14  LEU n 
1 15  SER n 
1 16  VAL n 
1 17  SER n 
1 18  VAL n 
1 19  GLY n 
1 20  GLU n 
1 21  THR n 
1 22  VAL n 
1 23  THR n 
1 24  LEU n 
1 25  THR n 
1 26  CYS n 
1 27  ARG n 
1 28  ALA n 
1 29  SER n 
1 30  GLU n 
1 31  ASN n 
1 32  ILE n 
1 33  TYR n 
1 34  SER n 
1 35  ASN n 
1 36  LEU n 
1 37  ALA n 
1 38  TRP n 
1 39  TYR n 
1 40  HIS n 
1 41  GLN n 
1 42  LYS n 
1 43  GLN n 
1 44  GLY n 
1 45  ILE n 
1 46  SER n 
1 47  PRO n 
1 48  GLN n 
1 49  LEU n 
1 50  LEU n 
1 51  VAL n 
1 52  TYR n 
1 53  ALA n 
1 54  ALA n 
1 55  ALA n 
1 56  LYS n 
1 57  LEU n 
1 58  ALA n 
1 59  ASP n 
1 60  GLY n 
1 61  VAL n 
1 62  PRO n 
1 63  SER n 
1 64  ARG n 
1 65  PHE n 
1 66  SER n 
1 67  GLY n 
1 68  SER n 
1 69  GLY n 
1 70  SER n 
1 71  GLY n 
1 72  THR n 
1 73  GLN n 
1 74  TYR n 
1 75  SER n 
1 76  PHE n 
1 77  LYS n 
1 78  ILE n 
1 79  ASN n 
1 80  SER n 
1 81  LEU n 
1 82  GLN n 
1 83  SER n 
1 84  GLU n 
1 85  ASP n 
1 86  PHE n 
1 87  GLY n 
1 88  SER n 
1 89  TYR n 
1 90  TYR n 
1 91  CYS n 
1 92  GLN n 
1 93  HIS n 
1 94  PHE n 
1 95  TRP n 
1 96  GLY n 
1 97  THR n 
1 98  PRO n 
1 99  TRP n 
1 100 THR n 
1 101 PHE n 
1 102 GLY n 
1 103 GLY n 
1 104 GLY n 
1 105 THR n 
1 106 LYS n 
1 107 LEU n 
1 108 GLU n 
1 109 ILE n 
1 110 LYS n 
2 1   VAL n 
2 2   HIS n 
2 3   SER n 
2 4   GLN n 
2 5   VAL n 
2 6   GLN n 
2 7   LEU n 
2 8   GLN n 
2 9   GLN n 
2 10  PRO n 
2 11  GLY n 
2 12  THR n 
2 13  GLU n 
2 14  LEU n 
2 15  VAL n 
2 16  LYS n 
2 17  PRO n 
2 18  GLY n 
2 19  ALA n 
2 20  SER n 
2 21  VAL n 
2 22  LYS n 
2 23  LEU n 
2 24  SER n 
2 25  CYS n 
2 26  LYS n 
2 27  ALA n 
2 28  SER n 
2 29  GLY n 
2 30  TYR n 
2 31  THR n 
2 32  PHE n 
2 33  THR n 
2 34  SER n 
2 35  TYR n 
2 36  SER n 
2 37  VAL n 
2 38  HIS n 
2 39  TRP n 
2 40  VAL n 
2 41  LYS n 
2 42  GLN n 
2 43  ARG n 
2 44  PRO n 
2 45  GLY n 
2 46  GLN n 
2 47  GLY n 
2 48  LEU n 
2 49  GLU n 
2 50  TRP n 
2 51  ILE n 
2 52  GLY n 
2 53  SER n 
2 54  ILE n 
2 55  ASN n 
2 56  PRO n 
2 57  ASN n 
2 58  ASN n 
2 59  ASP n 
2 60  VAL n 
2 61  ALA n 
2 62  TYR n 
2 63  PHE n 
2 64  ASN n 
2 65  GLU n 
2 66  LYS n 
2 67  PHE n 
2 68  LYS n 
2 69  THR n 
2 70  LYS n 
2 71  ALA n 
2 72  THR n 
2 73  LEU n 
2 74  THR n 
2 75  VAL n 
2 76  ASP n 
2 77  ARG n 
2 78  SER n 
2 79  SER n 
2 80  SER n 
2 81  THR n 
2 82  ALA n 
2 83  TYR n 
2 84  MET n 
2 85  GLN n 
2 86  LEU n 
2 87  SER n 
2 88  SER n 
2 89  LEU n 
2 90  THR n 
2 91  PHE n 
2 92  GLU n 
2 93  ASP n 
2 94  SER n 
2 95  ALA n 
2 96  VAL n 
2 97  TYR n 
2 98  TYR n 
2 99  CYS n 
2 100 ALA n 
2 101 ARG n 
2 102 GLY n 
2 103 GLY n 
2 104 ILE n 
2 105 HIS n 
2 106 TYR n 
2 107 THR n 
2 108 TYR n 
2 109 ASP n 
2 110 GLY n 
2 111 TYR n 
2 112 TYR n 
2 113 PHE n 
2 114 ASP n 
2 115 TYR n 
2 116 TRP n 
2 117 GLY n 
2 118 GLN n 
2 119 GLY n 
2 120 THR n 
2 121 THR n 
2 122 LEU n 
2 123 THR n 
2 124 VAL n 
2 125 SER n 
2 126 SER n 
3 1   MET n 
3 2   ALA n 
3 3   LYS n 
3 4   LEU n 
3 5   GLU n 
3 6   THR n 
3 7   VAL n 
3 8   THR n 
3 9   LEU n 
3 10  GLY n 
3 11  ASN n 
3 12  ILE n 
3 13  GLY n 
3 14  LYS n 
3 15  ASP n 
3 16  GLY n 
3 17  LYS n 
3 18  GLN n 
3 19  THR n 
3 20  LEU n 
3 21  VAL n 
3 22  LEU n 
3 23  ASN n 
3 24  PRO n 
3 25  ARG n 
3 26  GLY n 
3 27  VAL n 
3 28  ASN n 
3 29  PRO n 
3 30  THR n 
3 31  ASN n 
3 32  GLY n 
3 33  VAL n 
3 34  ALA n 
3 35  SER n 
3 36  LEU n 
3 37  SER n 
3 38  GLN n 
3 39  ALA n 
3 40  GLY n 
3 41  ALA n 
3 42  VAL n 
3 43  PRO n 
3 44  ALA n 
3 45  LEU n 
3 46  GLU n 
3 47  LYS n 
3 48  ARG n 
3 49  VAL n 
3 50  THR n 
3 51  VAL n 
3 52  SER n 
3 53  VAL n 
3 54  SER n 
3 55  GLN n 
3 56  PRO n 
3 57  SER n 
3 58  ARG n 
3 59  ASN n 
3 60  ARG n 
3 61  LYS n 
3 62  ASN n 
3 63  TYR n 
3 64  LYS n 
3 65  VAL n 
3 66  GLN n 
3 67  VAL n 
3 68  LYS n 
3 69  ILE n 
3 70  GLN n 
3 71  ASN n 
3 72  PRO n 
3 73  THR n 
3 74  ALA n 
3 75  CYS n 
3 76  THR n 
3 77  ALA n 
3 78  ASN n 
3 79  GLY n 
3 80  SER n 
3 81  CYS n 
3 82  ASP n 
3 83  PRO n 
3 84  SER n 
3 85  VAL n 
3 86  THR n 
3 87  ARG n 
3 88  GLN n 
3 89  ALA n 
3 90  TYR n 
3 91  ALA n 
3 92  ASP n 
3 93  VAL n 
3 94  THR n 
3 95  PHE n 
3 96  SER n 
3 97  PHE n 
3 98  THR n 
3 99  GLN n 
3 100 TYR n 
3 101 SER n 
3 102 THR n 
3 103 ASP n 
3 104 GLU n 
3 105 GLU n 
3 106 ARG n 
3 107 ALA n 
3 108 PHE n 
3 109 VAL n 
3 110 ARG n 
3 111 THR n 
3 112 GLU n 
3 113 LEU n 
3 114 ALA n 
3 115 ALA n 
3 116 LEU n 
3 117 LEU n 
3 118 ALA n 
3 119 SER n 
3 120 PRO n 
3 121 LEU n 
3 122 LEU n 
3 123 ILE n 
3 124 ASP n 
3 125 ALA n 
3 126 ILE n 
3 127 ASP n 
3 128 GLN n 
3 129 LEU n 
3 130 ASN n 
3 131 PRO n 
3 132 ALA n 
3 133 TYR n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 110 ? ? ? ? ? ? ? ? ? 'Mus musculus'            10090   ? ? ? ? ? ? ? ? 'Homo sapiens'     9606 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 126 ? ? ? ? ? ? ? ? ? 'Mus musculus'            10090   ? ? ? ? ? ? ? ? 'Homo sapiens'     9606 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 133 ? ? ? ? ? ? ? ? ? 'Escherichia phage Qbeta' 2789016 ? ? ? ? ? ? ? ? 'Escherichia coli' 562  
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   VAL 1   16  ?   ?   ?   L . n 
A 1 2   HIS 2   17  ?   ?   ?   L . n 
A 1 3   SER 3   18  ?   ?   ?   L . n 
A 1 4   ASP 4   19  ?   ?   ?   L . n 
A 1 5   ILE 5   20  20  ILE ILE L . n 
A 1 6   GLN 6   21  21  GLN GLN L . n 
A 1 7   MET 7   22  22  MET MET L . n 
A 1 8   THR 8   23  23  THR THR L . n 
A 1 9   GLN 9   24  24  GLN GLN L . n 
A 1 10  SER 10  25  25  SER SER L . n 
A 1 11  PRO 11  26  26  PRO PRO L . n 
A 1 12  ALA 12  27  27  ALA ALA L . n 
A 1 13  SER 13  28  28  SER SER L . n 
A 1 14  LEU 14  29  29  LEU LEU L . n 
A 1 15  SER 15  30  30  SER SER L . n 
A 1 16  VAL 16  31  31  VAL VAL L . n 
A 1 17  SER 17  32  32  SER SER L . n 
A 1 18  VAL 18  33  33  VAL VAL L . n 
A 1 19  GLY 19  34  34  GLY GLY L . n 
A 1 20  GLU 20  35  35  GLU GLU L . n 
A 1 21  THR 21  36  36  THR THR L . n 
A 1 22  VAL 22  37  37  VAL VAL L . n 
A 1 23  THR 23  38  38  THR THR L . n 
A 1 24  LEU 24  39  39  LEU LEU L . n 
A 1 25  THR 25  40  40  THR THR L . n 
A 1 26  CYS 26  41  41  CYS CYS L . n 
A 1 27  ARG 27  42  42  ARG ARG L . n 
A 1 28  ALA 28  43  43  ALA ALA L . n 
A 1 29  SER 29  44  44  SER SER L . n 
A 1 30  GLU 30  45  45  GLU GLU L . n 
A 1 31  ASN 31  46  46  ASN ASN L . n 
A 1 32  ILE 32  47  47  ILE ILE L . n 
A 1 33  TYR 33  48  48  TYR TYR L . n 
A 1 34  SER 34  49  49  SER SER L . n 
A 1 35  ASN 35  50  50  ASN ASN L . n 
A 1 36  LEU 36  51  51  LEU LEU L . n 
A 1 37  ALA 37  52  52  ALA ALA L . n 
A 1 38  TRP 38  53  53  TRP TRP L . n 
A 1 39  TYR 39  54  54  TYR TYR L . n 
A 1 40  HIS 40  55  55  HIS HIS L . n 
A 1 41  GLN 41  56  56  GLN GLN L . n 
A 1 42  LYS 42  57  57  LYS LYS L . n 
A 1 43  GLN 43  58  58  GLN GLN L . n 
A 1 44  GLY 44  59  59  GLY GLY L . n 
A 1 45  ILE 45  60  60  ILE ILE L . n 
A 1 46  SER 46  61  61  SER SER L . n 
A 1 47  PRO 47  62  62  PRO PRO L . n 
A 1 48  GLN 48  63  63  GLN GLN L . n 
A 1 49  LEU 49  64  64  LEU LEU L . n 
A 1 50  LEU 50  65  65  LEU LEU L . n 
A 1 51  VAL 51  66  66  VAL VAL L . n 
A 1 52  TYR 52  67  67  TYR TYR L . n 
A 1 53  ALA 53  68  68  ALA ALA L . n 
A 1 54  ALA 54  69  69  ALA ALA L . n 
A 1 55  ALA 55  70  70  ALA ALA L . n 
A 1 56  LYS 56  71  71  LYS LYS L . n 
A 1 57  LEU 57  72  72  LEU LEU L . n 
A 1 58  ALA 58  73  73  ALA ALA L . n 
A 1 59  ASP 59  74  74  ASP ASP L . n 
A 1 60  GLY 60  75  75  GLY GLY L . n 
A 1 61  VAL 61  76  76  VAL VAL L . n 
A 1 62  PRO 62  77  77  PRO PRO L . n 
A 1 63  SER 63  78  78  SER SER L . n 
A 1 64  ARG 64  79  79  ARG ARG L . n 
A 1 65  PHE 65  80  80  PHE PHE L . n 
A 1 66  SER 66  81  81  SER SER L . n 
A 1 67  GLY 67  82  82  GLY GLY L . n 
A 1 68  SER 68  83  83  SER SER L . n 
A 1 69  GLY 69  84  84  GLY GLY L . n 
A 1 70  SER 70  85  85  SER SER L . n 
A 1 71  GLY 71  86  86  GLY GLY L . n 
A 1 72  THR 72  87  87  THR THR L . n 
A 1 73  GLN 73  88  88  GLN GLN L . n 
A 1 74  TYR 74  89  89  TYR TYR L . n 
A 1 75  SER 75  90  90  SER SER L . n 
A 1 76  PHE 76  91  91  PHE PHE L . n 
A 1 77  LYS 77  92  92  LYS LYS L . n 
A 1 78  ILE 78  93  93  ILE ILE L . n 
A 1 79  ASN 79  94  94  ASN ASN L . n 
A 1 80  SER 80  95  95  SER SER L . n 
A 1 81  LEU 81  96  96  LEU LEU L . n 
A 1 82  GLN 82  97  97  GLN GLN L . n 
A 1 83  SER 83  98  98  SER SER L . n 
A 1 84  GLU 84  99  99  GLU GLU L . n 
A 1 85  ASP 85  100 100 ASP ASP L . n 
A 1 86  PHE 86  101 101 PHE PHE L . n 
A 1 87  GLY 87  102 102 GLY GLY L . n 
A 1 88  SER 88  103 103 SER SER L . n 
A 1 89  TYR 89  104 104 TYR TYR L . n 
A 1 90  TYR 90  105 105 TYR TYR L . n 
A 1 91  CYS 91  106 106 CYS CYS L . n 
A 1 92  GLN 92  107 107 GLN GLN L . n 
A 1 93  HIS 93  108 108 HIS HIS L . n 
A 1 94  PHE 94  109 109 PHE PHE L . n 
A 1 95  TRP 95  110 110 TRP TRP L . n 
A 1 96  GLY 96  111 111 GLY GLY L . n 
A 1 97  THR 97  112 112 THR THR L . n 
A 1 98  PRO 98  113 113 PRO PRO L . n 
A 1 99  TRP 99  114 114 TRP TRP L . n 
A 1 100 THR 100 115 115 THR THR L . n 
A 1 101 PHE 101 116 116 PHE PHE L . n 
A 1 102 GLY 102 117 117 GLY GLY L . n 
A 1 103 GLY 103 118 118 GLY GLY L . n 
A 1 104 GLY 104 119 119 GLY GLY L . n 
A 1 105 THR 105 120 120 THR THR L . n 
A 1 106 LYS 106 121 121 LYS LYS L . n 
A 1 107 LEU 107 122 122 LEU LEU L . n 
A 1 108 GLU 108 123 ?   ?   ?   L . n 
A 1 109 ILE 109 124 ?   ?   ?   L . n 
A 1 110 LYS 110 125 ?   ?   ?   L . n 
B 2 1   VAL 1   17  ?   ?   ?   H . n 
B 2 2   HIS 2   18  ?   ?   ?   H . n 
B 2 3   SER 3   19  ?   ?   ?   H . n 
B 2 4   GLN 4   20  ?   ?   ?   H . n 
B 2 5   VAL 5   21  21  VAL VAL H . n 
B 2 6   GLN 6   22  22  GLN GLN H . n 
B 2 7   LEU 7   23  23  LEU LEU H . n 
B 2 8   GLN 8   24  24  GLN GLN H . n 
B 2 9   GLN 9   25  25  GLN GLN H . n 
B 2 10  PRO 10  26  26  PRO PRO H . n 
B 2 11  GLY 11  27  27  GLY GLY H . n 
B 2 12  THR 12  28  28  THR THR H . n 
B 2 13  GLU 13  29  29  GLU GLU H . n 
B 2 14  LEU 14  30  30  LEU LEU H . n 
B 2 15  VAL 15  31  31  VAL VAL H . n 
B 2 16  LYS 16  32  32  LYS LYS H . n 
B 2 17  PRO 17  33  33  PRO PRO H . n 
B 2 18  GLY 18  34  34  GLY GLY H . n 
B 2 19  ALA 19  35  35  ALA ALA H . n 
B 2 20  SER 20  36  36  SER SER H . n 
B 2 21  VAL 21  37  37  VAL VAL H . n 
B 2 22  LYS 22  38  38  LYS LYS H . n 
B 2 23  LEU 23  39  39  LEU LEU H . n 
B 2 24  SER 24  40  40  SER SER H . n 
B 2 25  CYS 25  41  41  CYS CYS H . n 
B 2 26  LYS 26  42  42  LYS LYS H . n 
B 2 27  ALA 27  43  43  ALA ALA H . n 
B 2 28  SER 28  44  44  SER SER H . n 
B 2 29  GLY 29  45  45  GLY GLY H . n 
B 2 30  TYR 30  46  46  TYR TYR H . n 
B 2 31  THR 31  47  47  THR THR H . n 
B 2 32  PHE 32  48  48  PHE PHE H . n 
B 2 33  THR 33  49  49  THR THR H . n 
B 2 34  SER 34  50  50  SER SER H . n 
B 2 35  TYR 35  51  51  TYR TYR H . n 
B 2 36  SER 36  52  52  SER SER H . n 
B 2 37  VAL 37  53  53  VAL VAL H . n 
B 2 38  HIS 38  54  54  HIS HIS H . n 
B 2 39  TRP 39  55  55  TRP TRP H . n 
B 2 40  VAL 40  56  56  VAL VAL H . n 
B 2 41  LYS 41  57  57  LYS LYS H . n 
B 2 42  GLN 42  58  58  GLN GLN H . n 
B 2 43  ARG 43  59  59  ARG ARG H . n 
B 2 44  PRO 44  60  60  PRO PRO H . n 
B 2 45  GLY 45  61  61  GLY GLY H . n 
B 2 46  GLN 46  62  62  GLN GLN H . n 
B 2 47  GLY 47  63  63  GLY GLY H . n 
B 2 48  LEU 48  64  64  LEU LEU H . n 
B 2 49  GLU 49  65  65  GLU GLU H . n 
B 2 50  TRP 50  66  66  TRP TRP H . n 
B 2 51  ILE 51  67  67  ILE ILE H . n 
B 2 52  GLY 52  68  68  GLY GLY H . n 
B 2 53  SER 53  69  69  SER SER H . n 
B 2 54  ILE 54  70  70  ILE ILE H . n 
B 2 55  ASN 55  71  71  ASN ASN H . n 
B 2 56  PRO 56  72  72  PRO PRO H . n 
B 2 57  ASN 57  73  73  ASN ASN H . n 
B 2 58  ASN 58  74  74  ASN ASN H . n 
B 2 59  ASP 59  75  75  ASP ASP H . n 
B 2 60  VAL 60  76  76  VAL VAL H . n 
B 2 61  ALA 61  77  77  ALA ALA H . n 
B 2 62  TYR 62  78  78  TYR TYR H . n 
B 2 63  PHE 63  79  79  PHE PHE H . n 
B 2 64  ASN 64  80  80  ASN ASN H . n 
B 2 65  GLU 65  81  81  GLU GLU H . n 
B 2 66  LYS 66  82  82  LYS LYS H . n 
B 2 67  PHE 67  83  83  PHE PHE H . n 
B 2 68  LYS 68  84  84  LYS LYS H . n 
B 2 69  THR 69  85  85  THR THR H . n 
B 2 70  LYS 70  86  86  LYS LYS H . n 
B 2 71  ALA 71  87  87  ALA ALA H . n 
B 2 72  THR 72  88  88  THR THR H . n 
B 2 73  LEU 73  89  89  LEU LEU H . n 
B 2 74  THR 74  90  90  THR THR H . n 
B 2 75  VAL 75  91  91  VAL VAL H . n 
B 2 76  ASP 76  92  92  ASP ASP H . n 
B 2 77  ARG 77  93  93  ARG ARG H . n 
B 2 78  SER 78  94  94  SER SER H . n 
B 2 79  SER 79  95  95  SER SER H . n 
B 2 80  SER 80  96  96  SER SER H . n 
B 2 81  THR 81  97  97  THR THR H . n 
B 2 82  ALA 82  98  98  ALA ALA H . n 
B 2 83  TYR 83  99  99  TYR TYR H . n 
B 2 84  MET 84  100 100 MET MET H . n 
B 2 85  GLN 85  101 101 GLN GLN H . n 
B 2 86  LEU 86  102 102 LEU LEU H . n 
B 2 87  SER 87  103 103 SER SER H . n 
B 2 88  SER 88  104 104 SER SER H . n 
B 2 89  LEU 89  105 105 LEU LEU H . n 
B 2 90  THR 90  106 106 THR THR H . n 
B 2 91  PHE 91  107 107 PHE PHE H . n 
B 2 92  GLU 92  108 108 GLU GLU H . n 
B 2 93  ASP 93  109 109 ASP ASP H . n 
B 2 94  SER 94  110 110 SER SER H . n 
B 2 95  ALA 95  111 111 ALA ALA H . n 
B 2 96  VAL 96  112 112 VAL VAL H . n 
B 2 97  TYR 97  113 113 TYR TYR H . n 
B 2 98  TYR 98  114 114 TYR TYR H . n 
B 2 99  CYS 99  115 115 CYS CYS H . n 
B 2 100 ALA 100 116 116 ALA ALA H . n 
B 2 101 ARG 101 117 117 ARG ARG H . n 
B 2 102 GLY 102 118 118 GLY GLY H . n 
B 2 103 GLY 103 119 119 GLY GLY H . n 
B 2 104 ILE 104 120 120 ILE ILE H . n 
B 2 105 HIS 105 121 121 HIS HIS H . n 
B 2 106 TYR 106 122 122 TYR TYR H . n 
B 2 107 THR 107 123 123 THR THR H . n 
B 2 108 TYR 108 124 124 TYR TYR H . n 
B 2 109 ASP 109 125 125 ASP ASP H . n 
B 2 110 GLY 110 126 126 GLY GLY H . n 
B 2 111 TYR 111 127 127 TYR TYR H . n 
B 2 112 TYR 112 128 128 TYR TYR H . n 
B 2 113 PHE 113 129 129 PHE PHE H . n 
B 2 114 ASP 114 130 130 ASP ASP H . n 
B 2 115 TYR 115 131 131 TYR TYR H . n 
B 2 116 TRP 116 132 132 TRP TRP H . n 
B 2 117 GLY 117 133 133 GLY GLY H . n 
B 2 118 GLN 118 134 134 GLN GLN H . n 
B 2 119 GLY 119 135 135 GLY GLY H . n 
B 2 120 THR 120 136 136 THR THR H . n 
B 2 121 THR 121 137 137 THR THR H . n 
B 2 122 LEU 122 138 138 LEU LEU H . n 
B 2 123 THR 123 139 139 THR THR H . n 
B 2 124 VAL 124 140 140 VAL VAL H . n 
B 2 125 SER 125 141 ?   ?   ?   H . n 
B 2 126 SER 126 142 ?   ?   ?   H . n 
C 3 1   MET 1   0   ?   ?   ?   c . n 
C 3 2   ALA 2   1   1   ALA ALA c . n 
C 3 3   LYS 3   2   2   LYS LYS c . n 
C 3 4   LEU 4   3   3   LEU LEU c . n 
C 3 5   GLU 5   4   4   GLU GLU c . n 
C 3 6   THR 6   5   5   THR THR c . n 
C 3 7   VAL 7   6   6   VAL VAL c . n 
C 3 8   THR 8   7   7   THR THR c . n 
C 3 9   LEU 9   8   8   LEU LEU c . n 
C 3 10  GLY 10  9   9   GLY GLY c . n 
C 3 11  ASN 11  10  10  ASN ASN c . n 
C 3 12  ILE 12  11  11  ILE ILE c . n 
C 3 13  GLY 13  12  12  GLY GLY c . n 
C 3 14  LYS 14  13  13  LYS LYS c . n 
C 3 15  ASP 15  14  14  ASP ASP c . n 
C 3 16  GLY 16  15  15  GLY GLY c . n 
C 3 17  LYS 17  16  16  LYS LYS c . n 
C 3 18  GLN 18  17  17  GLN GLN c . n 
C 3 19  THR 19  18  18  THR THR c . n 
C 3 20  LEU 20  19  19  LEU LEU c . n 
C 3 21  VAL 21  20  20  VAL VAL c . n 
C 3 22  LEU 22  21  21  LEU LEU c . n 
C 3 23  ASN 23  22  22  ASN ASN c . n 
C 3 24  PRO 24  23  23  PRO PRO c . n 
C 3 25  ARG 25  24  24  ARG ARG c . n 
C 3 26  GLY 26  25  25  GLY GLY c . n 
C 3 27  VAL 27  26  26  VAL VAL c . n 
C 3 28  ASN 28  27  27  ASN ASN c . n 
C 3 29  PRO 29  28  28  PRO PRO c . n 
C 3 30  THR 30  29  29  THR THR c . n 
C 3 31  ASN 31  30  30  ASN ASN c . n 
C 3 32  GLY 32  31  31  GLY GLY c . n 
C 3 33  VAL 33  32  32  VAL VAL c . n 
C 3 34  ALA 34  33  33  ALA ALA c . n 
C 3 35  SER 35  34  34  SER SER c . n 
C 3 36  LEU 36  35  35  LEU LEU c . n 
C 3 37  SER 37  36  36  SER SER c . n 
C 3 38  GLN 38  37  37  GLN GLN c . n 
C 3 39  ALA 39  38  38  ALA ALA c . n 
C 3 40  GLY 40  39  39  GLY GLY c . n 
C 3 41  ALA 41  40  40  ALA ALA c . n 
C 3 42  VAL 42  41  41  VAL VAL c . n 
C 3 43  PRO 43  42  42  PRO PRO c . n 
C 3 44  ALA 44  43  43  ALA ALA c . n 
C 3 45  LEU 45  44  44  LEU LEU c . n 
C 3 46  GLU 46  45  45  GLU GLU c . n 
C 3 47  LYS 47  46  46  LYS LYS c . n 
C 3 48  ARG 48  47  47  ARG ARG c . n 
C 3 49  VAL 49  48  48  VAL VAL c . n 
C 3 50  THR 50  49  49  THR THR c . n 
C 3 51  VAL 51  50  50  VAL VAL c . n 
C 3 52  SER 52  51  51  SER SER c . n 
C 3 53  VAL 53  52  52  VAL VAL c . n 
C 3 54  SER 54  53  53  SER SER c . n 
C 3 55  GLN 55  54  54  GLN GLN c . n 
C 3 56  PRO 56  55  55  PRO PRO c . n 
C 3 57  SER 57  56  56  SER SER c . n 
C 3 58  ARG 58  57  57  ARG ARG c . n 
C 3 59  ASN 59  58  58  ASN ASN c . n 
C 3 60  ARG 60  59  59  ARG ARG c . n 
C 3 61  LYS 61  60  60  LYS LYS c . n 
C 3 62  ASN 62  61  61  ASN ASN c . n 
C 3 63  TYR 63  62  62  TYR TYR c . n 
C 3 64  LYS 64  63  63  LYS LYS c . n 
C 3 65  VAL 65  64  64  VAL VAL c . n 
C 3 66  GLN 66  65  65  GLN GLN c . n 
C 3 67  VAL 67  66  66  VAL VAL c . n 
C 3 68  LYS 68  67  67  LYS LYS c . n 
C 3 69  ILE 69  68  68  ILE ILE c . n 
C 3 70  GLN 70  69  69  GLN GLN c . n 
C 3 71  ASN 71  70  70  ASN ASN c . n 
C 3 72  PRO 72  71  71  PRO PRO c . n 
C 3 73  THR 73  72  72  THR THR c . n 
C 3 74  ALA 74  73  73  ALA ALA c . n 
C 3 75  CYS 75  74  74  CYS CYS c . n 
C 3 76  THR 76  75  75  THR THR c . n 
C 3 77  ALA 77  76  76  ALA ALA c . n 
C 3 78  ASN 78  77  77  ASN ASN c . n 
C 3 79  GLY 79  78  78  GLY GLY c . n 
C 3 80  SER 80  79  79  SER SER c . n 
C 3 81  CYS 81  80  80  CYS CYS c . n 
C 3 82  ASP 82  81  81  ASP ASP c . n 
C 3 83  PRO 83  82  82  PRO PRO c . n 
C 3 84  SER 84  83  83  SER SER c . n 
C 3 85  VAL 85  84  84  VAL VAL c . n 
C 3 86  THR 86  85  85  THR THR c . n 
C 3 87  ARG 87  86  86  ARG ARG c . n 
C 3 88  GLN 88  87  87  GLN GLN c . n 
C 3 89  ALA 89  88  88  ALA ALA c . n 
C 3 90  TYR 90  89  89  TYR TYR c . n 
C 3 91  ALA 91  90  90  ALA ALA c . n 
C 3 92  ASP 92  91  91  ASP ASP c . n 
C 3 93  VAL 93  92  92  VAL VAL c . n 
C 3 94  THR 94  93  93  THR THR c . n 
C 3 95  PHE 95  94  94  PHE PHE c . n 
C 3 96  SER 96  95  95  SER SER c . n 
C 3 97  PHE 97  96  96  PHE PHE c . n 
C 3 98  THR 98  97  97  THR THR c . n 
C 3 99  GLN 99  98  98  GLN GLN c . n 
C 3 100 TYR 100 99  99  TYR TYR c . n 
C 3 101 SER 101 100 100 SER SER c . n 
C 3 102 THR 102 101 101 THR THR c . n 
C 3 103 ASP 103 102 102 ASP ASP c . n 
C 3 104 GLU 104 103 103 GLU GLU c . n 
C 3 105 GLU 105 104 104 GLU GLU c . n 
C 3 106 ARG 106 105 105 ARG ARG c . n 
C 3 107 ALA 107 106 106 ALA ALA c . n 
C 3 108 PHE 108 107 107 PHE PHE c . n 
C 3 109 VAL 109 108 108 VAL VAL c . n 
C 3 110 ARG 110 109 109 ARG ARG c . n 
C 3 111 THR 111 110 110 THR THR c . n 
C 3 112 GLU 112 111 111 GLU GLU c . n 
C 3 113 LEU 113 112 112 LEU LEU c . n 
C 3 114 ALA 114 113 113 ALA ALA c . n 
C 3 115 ALA 115 114 114 ALA ALA c . n 
C 3 116 LEU 116 115 115 LEU LEU c . n 
C 3 117 LEU 117 116 116 LEU LEU c . n 
C 3 118 ALA 118 117 117 ALA ALA c . n 
C 3 119 SER 119 118 118 SER SER c . n 
C 3 120 PRO 120 119 119 PRO PRO c . n 
C 3 121 LEU 121 120 120 LEU LEU c . n 
C 3 122 LEU 122 121 121 LEU LEU c . n 
C 3 123 ILE 123 122 122 ILE ILE c . n 
C 3 124 ASP 124 123 123 ASP ASP c . n 
C 3 125 ALA 125 124 124 ALA ALA c . n 
C 3 126 ILE 126 125 125 ILE ILE c . n 
C 3 127 ASP 127 126 126 ASP ASP c . n 
C 3 128 GLN 128 127 127 GLN GLN c . n 
C 3 129 LEU 129 128 128 LEU LEU c . n 
C 3 130 ASN 130 129 129 ASN ASN c . n 
C 3 131 PRO 131 130 130 PRO PRO c . n 
C 3 132 ALA 132 131 131 ALA ALA c . n 
C 3 133 TYR 133 132 ?   ?   ?   c . n 
D 3 1   MET 1   0   ?   ?   ?   C . n 
D 3 2   ALA 2   1   1   ALA ALA C . n 
D 3 3   LYS 3   2   2   LYS LYS C . n 
D 3 4   LEU 4   3   3   LEU LEU C . n 
D 3 5   GLU 5   4   4   GLU GLU C . n 
D 3 6   THR 6   5   5   THR THR C . n 
D 3 7   VAL 7   6   6   VAL VAL C . n 
D 3 8   THR 8   7   7   THR THR C . n 
D 3 9   LEU 9   8   8   LEU LEU C . n 
D 3 10  GLY 10  9   9   GLY GLY C . n 
D 3 11  ASN 11  10  10  ASN ASN C . n 
D 3 12  ILE 12  11  11  ILE ILE C . n 
D 3 13  GLY 13  12  12  GLY GLY C . n 
D 3 14  LYS 14  13  13  LYS LYS C . n 
D 3 15  ASP 15  14  14  ASP ASP C . n 
D 3 16  GLY 16  15  15  GLY GLY C . n 
D 3 17  LYS 17  16  16  LYS LYS C . n 
D 3 18  GLN 18  17  17  GLN GLN C . n 
D 3 19  THR 19  18  18  THR THR C . n 
D 3 20  LEU 20  19  19  LEU LEU C . n 
D 3 21  VAL 21  20  20  VAL VAL C . n 
D 3 22  LEU 22  21  21  LEU LEU C . n 
D 3 23  ASN 23  22  22  ASN ASN C . n 
D 3 24  PRO 24  23  23  PRO PRO C . n 
D 3 25  ARG 25  24  24  ARG ARG C . n 
D 3 26  GLY 26  25  25  GLY GLY C . n 
D 3 27  VAL 27  26  26  VAL VAL C . n 
D 3 28  ASN 28  27  27  ASN ASN C . n 
D 3 29  PRO 29  28  28  PRO PRO C . n 
D 3 30  THR 30  29  29  THR THR C . n 
D 3 31  ASN 31  30  30  ASN ASN C . n 
D 3 32  GLY 32  31  31  GLY GLY C . n 
D 3 33  VAL 33  32  32  VAL VAL C . n 
D 3 34  ALA 34  33  33  ALA ALA C . n 
D 3 35  SER 35  34  34  SER SER C . n 
D 3 36  LEU 36  35  35  LEU LEU C . n 
D 3 37  SER 37  36  36  SER SER C . n 
D 3 38  GLN 38  37  37  GLN GLN C . n 
D 3 39  ALA 39  38  38  ALA ALA C . n 
D 3 40  GLY 40  39  39  GLY GLY C . n 
D 3 41  ALA 41  40  40  ALA ALA C . n 
D 3 42  VAL 42  41  41  VAL VAL C . n 
D 3 43  PRO 43  42  42  PRO PRO C . n 
D 3 44  ALA 44  43  43  ALA ALA C . n 
D 3 45  LEU 45  44  44  LEU LEU C . n 
D 3 46  GLU 46  45  45  GLU GLU C . n 
D 3 47  LYS 47  46  46  LYS LYS C . n 
D 3 48  ARG 48  47  47  ARG ARG C . n 
D 3 49  VAL 49  48  48  VAL VAL C . n 
D 3 50  THR 50  49  49  THR THR C . n 
D 3 51  VAL 51  50  50  VAL VAL C . n 
D 3 52  SER 52  51  51  SER SER C . n 
D 3 53  VAL 53  52  52  VAL VAL C . n 
D 3 54  SER 54  53  53  SER SER C . n 
D 3 55  GLN 55  54  54  GLN GLN C . n 
D 3 56  PRO 56  55  55  PRO PRO C . n 
D 3 57  SER 57  56  56  SER SER C . n 
D 3 58  ARG 58  57  57  ARG ARG C . n 
D 3 59  ASN 59  58  58  ASN ASN C . n 
D 3 60  ARG 60  59  59  ARG ARG C . n 
D 3 61  LYS 61  60  60  LYS LYS C . n 
D 3 62  ASN 62  61  61  ASN ASN C . n 
D 3 63  TYR 63  62  62  TYR TYR C . n 
D 3 64  LYS 64  63  63  LYS LYS C . n 
D 3 65  VAL 65  64  64  VAL VAL C . n 
D 3 66  GLN 66  65  65  GLN GLN C . n 
D 3 67  VAL 67  66  66  VAL VAL C . n 
D 3 68  LYS 68  67  67  LYS LYS C . n 
D 3 69  ILE 69  68  68  ILE ILE C . n 
D 3 70  GLN 70  69  69  GLN GLN C . n 
D 3 71  ASN 71  70  70  ASN ASN C . n 
D 3 72  PRO 72  71  71  PRO PRO C . n 
D 3 73  THR 73  72  72  THR THR C . n 
D 3 74  ALA 74  73  73  ALA ALA C . n 
D 3 75  CYS 75  74  74  CYS CYS C . n 
D 3 76  THR 76  75  75  THR THR C . n 
D 3 77  ALA 77  76  76  ALA ALA C . n 
D 3 78  ASN 78  77  77  ASN ASN C . n 
D 3 79  GLY 79  78  78  GLY GLY C . n 
D 3 80  SER 80  79  79  SER SER C . n 
D 3 81  CYS 81  80  80  CYS CYS C . n 
D 3 82  ASP 82  81  81  ASP ASP C . n 
D 3 83  PRO 83  82  82  PRO PRO C . n 
D 3 84  SER 84  83  83  SER SER C . n 
D 3 85  VAL 85  84  84  VAL VAL C . n 
D 3 86  THR 86  85  85  THR THR C . n 
D 3 87  ARG 87  86  86  ARG ARG C . n 
D 3 88  GLN 88  87  87  GLN GLN C . n 
D 3 89  ALA 89  88  88  ALA ALA C . n 
D 3 90  TYR 90  89  89  TYR TYR C . n 
D 3 91  ALA 91  90  90  ALA ALA C . n 
D 3 92  ASP 92  91  91  ASP ASP C . n 
D 3 93  VAL 93  92  92  VAL VAL C . n 
D 3 94  THR 94  93  93  THR THR C . n 
D 3 95  PHE 95  94  94  PHE PHE C . n 
D 3 96  SER 96  95  95  SER SER C . n 
D 3 97  PHE 97  96  96  PHE PHE C . n 
D 3 98  THR 98  97  97  THR THR C . n 
D 3 99  GLN 99  98  98  GLN GLN C . n 
D 3 100 TYR 100 99  99  TYR TYR C . n 
D 3 101 SER 101 100 100 SER SER C . n 
D 3 102 THR 102 101 101 THR THR C . n 
D 3 103 ASP 103 102 102 ASP ASP C . n 
D 3 104 GLU 104 103 103 GLU GLU C . n 
D 3 105 GLU 105 104 104 GLU GLU C . n 
D 3 106 ARG 106 105 105 ARG ARG C . n 
D 3 107 ALA 107 106 106 ALA ALA C . n 
D 3 108 PHE 108 107 107 PHE PHE C . n 
D 3 109 VAL 109 108 108 VAL VAL C . n 
D 3 110 ARG 110 109 109 ARG ARG C . n 
D 3 111 THR 111 110 110 THR THR C . n 
D 3 112 GLU 112 111 111 GLU GLU C . n 
D 3 113 LEU 113 112 112 LEU LEU C . n 
D 3 114 ALA 114 113 113 ALA ALA C . n 
D 3 115 ALA 115 114 114 ALA ALA C . n 
D 3 116 LEU 116 115 115 LEU LEU C . n 
D 3 117 LEU 117 116 116 LEU LEU C . n 
D 3 118 ALA 118 117 117 ALA ALA C . n 
D 3 119 SER 119 118 118 SER SER C . n 
D 3 120 PRO 120 119 119 PRO PRO C . n 
D 3 121 LEU 121 120 120 LEU LEU C . n 
D 3 122 LEU 122 121 121 LEU LEU C . n 
D 3 123 ILE 123 122 122 ILE ILE C . n 
D 3 124 ASP 124 123 123 ASP ASP C . n 
D 3 125 ALA 125 124 124 ALA ALA C . n 
D 3 126 ILE 126 125 125 ILE ILE C . n 
D 3 127 ASP 127 126 126 ASP ASP C . n 
D 3 128 GLN 128 127 127 GLN GLN C . n 
D 3 129 LEU 129 128 128 LEU LEU C . n 
D 3 130 ASN 130 129 129 ASN ASN C . n 
D 3 131 PRO 131 130 130 PRO PRO C . n 
D 3 132 ALA 132 131 131 ALA ALA C . n 
D 3 133 TYR 133 132 ?   ?   ?   C . n 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8W5F 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8W5F 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8W5F 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 8W5F 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.005 ? 3776 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 1.035 ? 5139 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 6.212 ? 523  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.050 ? 588  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.012 ? 665  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     8W5F 
_struct.title                        'Cryo-EM structure of Qb-Ab6' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8W5F 
_struct_keywords.text            'Qb, Antibody, cryo-EM, IMMUNE SYSTEM' 
_struct_keywords.pdbx_keywords   'IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 3 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 8W5F     8W5F   ? 1 ? 1 
2 PDB 8W5F     8W5F   ? 2 ? 1 
3 UNP A1_BPQBE Q8LTE1 ? 3 
;MAKLETVTLGNIGKDGKQTLVLNPRGVNPTNGVASLSQAGAVPALEKRVTVSVSQPSRNRKNYKVQVKIQNPTACTANGS
CDPSVTRQAYADVTFSFTQYSTDEERAFVRTELAALLASPLLIDAIDQLNPAY
;
1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8W5F L 1 ? 110 ? 8W5F   16 ? 125 ? 16 125 
2 2 8W5F H 1 ? 126 ? 8W5F   17 ? 142 ? 17 142 
3 3 8W5F c 1 ? 133 ? Q8LTE1 1  ? 133 ? 0  132 
4 3 8W5F C 1 ? 133 ? Q8LTE1 1  ? 133 ? 0  132 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 AA1 THR C 102 ? LEU C 117 ? THR c 101 LEU c 116 1 ? 16 
HELX_P HELX_P2 AA2 SER C 119 ? GLN C 128 ? SER c 118 GLN c 127 1 ? 10 
HELX_P HELX_P3 AA3 THR D 102 ? ALA D 118 ? THR C 101 ALA C 117 1 ? 17 
HELX_P HELX_P4 AA4 SER D 119 ? GLN D 128 ? SER C 118 GLN C 127 1 ? 10 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 26 SG ? ? ? 1_555 A CYS 91 SG ? ? L CYS 41 L CYS 106 1_555 ? ? ? ? ? ? ? 2.034 ? ? 
disulf2 disulf ? ? B CYS 25 SG ? ? ? 1_555 B CYS 99 SG ? ? H CYS 41 H CYS 115 1_555 ? ? ? ? ? ? ? 2.032 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 26 ? CYS A 91 ? CYS L 41 ? 1_555 CYS L 106 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS B 25 ? CYS B 99 ? CYS H 41 ? 1_555 CYS H 115 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4  ? 
AA2 ? 2  ? 
AA3 ? 4  ? 
AA4 ? 2  ? 
AA5 ? 4  ? 
AA6 ? 12 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1  2  ? anti-parallel 
AA1 2  3  ? anti-parallel 
AA1 3  4  ? anti-parallel 
AA2 1  2  ? anti-parallel 
AA3 1  2  ? anti-parallel 
AA3 2  3  ? anti-parallel 
AA3 3  4  ? anti-parallel 
AA4 1  2  ? parallel      
AA5 1  2  ? anti-parallel 
AA5 2  3  ? anti-parallel 
AA5 3  4  ? anti-parallel 
AA6 1  2  ? anti-parallel 
AA6 2  3  ? anti-parallel 
AA6 3  4  ? anti-parallel 
AA6 4  5  ? anti-parallel 
AA6 5  6  ? anti-parallel 
AA6 6  7  ? anti-parallel 
AA6 7  8  ? anti-parallel 
AA6 8  9  ? anti-parallel 
AA6 9  10 ? anti-parallel 
AA6 10 11 ? anti-parallel 
AA6 11 12 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1  THR A 8   ? GLN A 9   ? THR L 23  GLN L 24  
AA1 2  VAL A 22  ? ARG A 27  ? VAL L 37  ARG L 42  
AA1 3  GLN A 73  ? ILE A 78  ? GLN L 88  ILE L 93  
AA1 4  PHE A 65  ? GLY A 69  ? PHE L 80  GLY L 84  
AA2 1  LEU A 36  ? ALA A 37  ? LEU L 51  ALA L 52  
AA2 2  GLN A 92  ? HIS A 93  ? GLN L 107 HIS L 108 
AA3 1  GLN B 6   ? GLN B 8   ? GLN H 22  GLN H 24  
AA3 2  LEU B 23  ? SER B 28  ? LEU H 39  SER H 44  
AA3 3  THR B 81  ? MET B 84  ? THR H 97  MET H 100 
AA3 4  LEU B 73  ? ASP B 76  ? LEU H 89  ASP H 92  
AA4 1  GLU B 13  ? LEU B 14  ? GLU H 29  LEU H 30  
AA4 2  LEU B 122 ? THR B 123 ? LEU H 138 THR H 139 
AA5 1  ALA B 61  ? PHE B 63  ? ALA H 77  PHE H 79  
AA5 2  GLY B 52  ? ILE B 54  ? GLY H 68  ILE H 70  
AA5 3  VAL B 37  ? GLN B 42  ? VAL H 53  GLN H 58  
AA5 4  VAL B 96  ? ARG B 101 ? VAL H 112 ARG H 117 
AA6 1  VAL C 7   ? ILE C 12  ? VAL c 6   ILE c 11  
AA6 2  GLN C 18  ? PRO C 24  ? GLN c 17  PRO c 23  
AA6 3  LEU C 36  ? SER C 37  ? LEU c 35  SER c 36  
AA6 4  ARG C 48  ? VAL C 53  ? ARG c 47  VAL c 52  
AA6 5  VAL C 65  ? CYS C 75  ? VAL c 64  CYS c 74  
AA6 6  SER C 84  ? PHE C 95  ? SER c 83  PHE c 94  
AA6 7  SER D 84  ? THR D 98  ? SER C 83  THR C 97  
AA6 8  ASN D 62  ? CYS D 75  ? ASN C 61  CYS C 74  
AA6 9  ARG D 48  ? VAL D 53  ? ARG C 47  VAL C 52  
AA6 10 ALA D 34  ? GLN D 38  ? ALA C 33  GLN C 37  
AA6 11 LEU D 20  ? VAL D 27  ? LEU C 19  VAL C 26  
AA6 12 VAL D 7   ? LEU D 9   ? VAL C 6   LEU C 8   
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1  2  N THR A 8  ? N THR L 23 O ARG A 27  ? O ARG L 42  
AA1 2  3  N LEU A 24 ? N LEU L 39 O PHE A 76  ? O PHE L 91  
AA1 3  4  O SER A 75 ? O SER L 90 N SER A 68  ? N SER L 83  
AA2 1  2  N ALA A 37 ? N ALA L 52 O GLN A 92  ? O GLN L 107 
AA3 1  2  N GLN B 8  ? N GLN H 24 O LYS B 26  ? O LYS H 42  
AA3 2  3  N CYS B 25 ? N CYS H 41 O ALA B 82  ? O ALA H 98  
AA3 3  4  O TYR B 83 ? O TYR H 99 N THR B 74  ? N THR H 90  
AA4 1  2  N GLU B 13 ? N GLU H 29 O THR B 123 ? O THR H 139 
AA5 1  2  O TYR B 62 ? O TYR H 78 N SER B 53  ? N SER H 69  
AA5 2  3  O GLY B 52 ? O GLY H 68 N TRP B 39  ? N TRP H 55  
AA5 3  4  N HIS B 38 ? N HIS H 54 O ALA B 100 ? O ALA H 116 
AA6 1  2  N VAL C 7  ? N VAL c 6  O LEU C 22  ? O LEU c 21  
AA6 2  3  N ASN C 23 ? N ASN c 22 O SER C 37  ? O SER c 36  
AA6 3  4  N LEU C 36 ? N LEU c 35 O VAL C 49  ? O VAL c 48  
AA6 4  5  N SER C 52 ? N SER c 51 O GLN C 66  ? O GLN c 65  
AA6 5  6  N VAL C 65 ? N VAL c 64 O PHE C 95  ? O PHE c 94  
AA6 6  7  N THR C 94 ? N THR c 93 O ASP D 92  ? O ASP C 91  
AA6 7  8  O ARG D 87 ? O ARG C 86 N THR D 73  ? N THR C 72  
AA6 8  9  O LYS D 68 ? O LYS C 67 N THR D 50  ? N THR C 49  
AA6 9  10 O VAL D 51 ? O VAL C 50 N ALA D 34  ? N ALA C 33  
AA6 10 11 O SER D 35 ? O SER C 34 N ARG D 25  ? N ARG C 24  
AA6 11 12 O LEU D 22 ? O LEU C 21 N VAL D 7   ? N VAL C 6   
# 
_pdbx_entry_details.entry_id                   8W5F 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 PRO L 26  ? ? -37.40  130.81  
2  1 LEU L 29  ? ? 66.21   -6.61   
3  1 SER L 30  ? ? 44.39   -92.77  
4  1 VAL L 31  ? ? 45.41   124.39  
5  1 ALA L 69  ? ? 160.01  -49.08  
6  1 ALA L 73  ? ? -80.65  -71.28  
7  1 ASP L 74  ? ? -125.56 -59.29  
8  1 GLN L 97  ? ? 62.56   166.83  
9  1 GLU L 99  ? ? 162.10  -30.33  
10 1 SER L 103 ? ? 61.31   69.67   
11 1 PHE L 116 ? ? 65.22   174.74  
12 1 PRO H 26  ? ? -3.31   -146.07 
13 1 LYS H 32  ? ? 95.69   145.96  
14 1 TYR H 46  ? ? -141.29 28.70   
15 1 THR H 47  ? ? 57.80   70.46   
16 1 THR H 49  ? ? -81.60  48.83   
17 1 TRP H 66  ? ? 59.33   73.57   
18 1 ASN H 74  ? ? 75.04   -8.71   
19 1 GLN H 101 ? ? -92.80  -60.16  
20 1 GLU H 108 ? ? -92.96  57.75   
21 1 LYS c 13  ? ? 75.91   -66.83  
22 1 ARG c 59  ? ? 62.77   154.65  
23 1 PRO c 130 ? ? -69.31  -173.91 
24 1 GLU C 4   ? ? -126.58 -169.37 
25 1 LYS C 13  ? ? 63.22   -13.30  
26 1 ASP C 14  ? ? 177.47  160.83  
27 1 ASN C 61  ? ? -170.83 146.57  
28 1 ALA C 90  ? ? -163.66 115.11  
# 
loop_
_pdbx_validate_peptide_omega.id 
_pdbx_validate_peptide_omega.PDB_model_num 
_pdbx_validate_peptide_omega.auth_comp_id_1 
_pdbx_validate_peptide_omega.auth_asym_id_1 
_pdbx_validate_peptide_omega.auth_seq_id_1 
_pdbx_validate_peptide_omega.PDB_ins_code_1 
_pdbx_validate_peptide_omega.label_alt_id_1 
_pdbx_validate_peptide_omega.auth_comp_id_2 
_pdbx_validate_peptide_omega.auth_asym_id_2 
_pdbx_validate_peptide_omega.auth_seq_id_2 
_pdbx_validate_peptide_omega.PDB_ins_code_2 
_pdbx_validate_peptide_omega.label_alt_id_2 
_pdbx_validate_peptide_omega.omega 
1 1 SER L 25 ? ? PRO L 26 ? ? -137.47 
2 1 ILE c 11 ? ? GLY c 12 ? ? -138.43 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8W5F 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8W5F 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.3 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               241562 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Complex of Qb-Ab6' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3' 
# 
_em_imaging.entry_id                        8W5F 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             1500 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8W5F 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8W5F 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 L VAL 16  ? A VAL 1   
2  1 Y 1 L HIS 17  ? A HIS 2   
3  1 Y 1 L SER 18  ? A SER 3   
4  1 Y 1 L ASP 19  ? A ASP 4   
5  1 Y 1 L GLU 123 ? A GLU 108 
6  1 Y 1 L ILE 124 ? A ILE 109 
7  1 Y 1 L LYS 125 ? A LYS 110 
8  1 Y 1 H VAL 17  ? B VAL 1   
9  1 Y 1 H HIS 18  ? B HIS 2   
10 1 Y 1 H SER 19  ? B SER 3   
11 1 Y 1 H GLN 20  ? B GLN 4   
12 1 Y 1 H SER 141 ? B SER 125 
13 1 Y 1 H SER 142 ? B SER 126 
14 1 Y 1 c MET 0   ? C MET 1   
15 1 Y 1 c TYR 132 ? C TYR 133 
16 1 Y 1 C MET 0   ? D MET 1   
17 1 Y 1 C TYR 132 ? D TYR 133 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-08-26 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8W5F 
_em_admin.last_update        2025-02-26 
_em_admin.map_release_date   2025-02-26 
_em_admin.title              'Cryo-EM structure of Qb-Ab6' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          10088 
_em_entity_assembly_naturalsource.organism             Mus 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K2 SUMMIT (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ? ? 
MASKING                         ? 3  ? ? ? ? ? 
'CTF CORRECTION'                ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ? ? 
'MODEL FITTING'                 ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'              ? 8  ? ? ? ? ? 
OTHER                           ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ? ? 
CLASSIFICATION                  ? 12 1 ? ? ? ? 
RECONSTRUCTION                  ? 13 1 ? ? ? ? 
'VOLUME SELECTION'              ? 14 1 1 1 ? ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ? ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ? ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ? ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ? ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Natural Science Foundation of China (NSFC)' China 81991495    1 
'National Natural Science Foundation of China (NSFC)' China 32241029    2 
'Chinese Academy of Sciences'                         China XDB29050600 3 
'Chinese Academy of Sciences'                         China XDB37010100 4 
# 
_atom_sites.entry_id                    8W5F 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . ILE A 1 5   ? 142.002 130.494 109.323 1.00 61.24  ? 20  ILE L N   1 
ATOM 2    C CA  . ILE A 1 5   ? 141.425 131.672 109.958 1.00 61.24  ? 20  ILE L CA  1 
ATOM 3    C C   . ILE A 1 5   ? 141.266 131.433 111.451 1.00 61.24  ? 20  ILE L C   1 
ATOM 4    O O   . ILE A 1 5   ? 140.604 130.485 111.869 1.00 61.24  ? 20  ILE L O   1 
ATOM 5    C CB  . ILE A 1 5   ? 140.079 132.045 109.320 1.00 61.24  ? 20  ILE L CB  1 
ATOM 6    C CG1 . ILE A 1 5   ? 140.296 132.629 107.925 1.00 61.24  ? 20  ILE L CG1 1 
ATOM 7    C CG2 . ILE A 1 5   ? 139.334 133.036 110.192 1.00 61.24  ? 20  ILE L CG2 1 
ATOM 8    C CD1 . ILE A 1 5   ? 139.028 133.091 107.253 1.00 61.24  ? 20  ILE L CD1 1 
ATOM 9    N N   . GLN A 1 6   ? 141.879 132.298 112.255 1.00 65.41  ? 21  GLN L N   1 
ATOM 10   C CA  . GLN A 1 6   ? 141.818 132.210 113.706 1.00 65.41  ? 21  GLN L CA  1 
ATOM 11   C C   . GLN A 1 6   ? 141.074 133.420 114.246 1.00 65.41  ? 21  GLN L C   1 
ATOM 12   O O   . GLN A 1 6   ? 141.400 134.560 113.899 1.00 65.41  ? 21  GLN L O   1 
ATOM 13   C CB  . GLN A 1 6   ? 143.220 132.134 114.316 1.00 65.41  ? 21  GLN L CB  1 
ATOM 14   C CG  . GLN A 1 6   ? 144.142 131.141 113.632 1.00 65.41  ? 21  GLN L CG  1 
ATOM 15   C CD  . GLN A 1 6   ? 144.998 131.789 112.561 1.00 65.41  ? 21  GLN L CD  1 
ATOM 16   O OE1 . GLN A 1 6   ? 145.186 133.005 112.553 1.00 65.41  ? 21  GLN L OE1 1 
ATOM 17   N NE2 . GLN A 1 6   ? 145.520 130.978 111.649 1.00 65.41  ? 21  GLN L NE2 1 
ATOM 18   N N   . MET A 1 7   ? 140.081 133.172 115.093 1.00 65.13  ? 22  MET L N   1 
ATOM 19   C CA  . MET A 1 7   ? 139.277 134.227 115.690 1.00 65.13  ? 22  MET L CA  1 
ATOM 20   C C   . MET A 1 7   ? 139.825 134.587 117.062 1.00 65.13  ? 22  MET L C   1 
ATOM 21   O O   . MET A 1 7   ? 140.046 133.712 117.904 1.00 65.13  ? 22  MET L O   1 
ATOM 22   C CB  . MET A 1 7   ? 137.816 133.794 115.810 1.00 65.13  ? 22  MET L CB  1 
ATOM 23   C CG  . MET A 1 7   ? 137.219 133.280 114.515 1.00 65.13  ? 22  MET L CG  1 
ATOM 24   S SD  . MET A 1 7   ? 136.490 134.594 113.525 1.00 65.13  ? 22  MET L SD  1 
ATOM 25   C CE  . MET A 1 7   ? 134.837 134.642 114.206 1.00 65.13  ? 22  MET L CE  1 
ATOM 26   N N   . THR A 1 8   ? 140.046 135.881 117.282 1.00 71.06  ? 23  THR L N   1 
ATOM 27   C CA  . THR A 1 8   ? 140.526 136.392 118.560 1.00 71.06  ? 23  THR L CA  1 
ATOM 28   C C   . THR A 1 8   ? 139.444 137.274 119.158 1.00 71.06  ? 23  THR L C   1 
ATOM 29   O O   . THR A 1 8   ? 139.026 138.255 118.535 1.00 71.06  ? 23  THR L O   1 
ATOM 30   C CB  . THR A 1 8   ? 141.829 137.177 118.394 1.00 71.06  ? 23  THR L CB  1 
ATOM 31   O OG1 . THR A 1 8   ? 141.604 138.306 117.541 1.00 71.06  ? 23  THR L OG1 1 
ATOM 32   C CG2 . THR A 1 8   ? 142.905 136.296 117.783 1.00 71.06  ? 23  THR L CG2 1 
ATOM 33   N N   . GLN A 1 9   ? 138.996 136.930 120.358 1.00 70.80  ? 24  GLN L N   1 
ATOM 34   C CA  . GLN A 1 9   ? 137.906 137.645 120.996 1.00 70.80  ? 24  GLN L CA  1 
ATOM 35   C C   . GLN A 1 9   ? 138.468 138.725 121.924 1.00 70.80  ? 24  GLN L C   1 
ATOM 36   O O   . GLN A 1 9   ? 139.674 138.812 122.161 1.00 70.80  ? 24  GLN L O   1 
ATOM 37   C CB  . GLN A 1 9   ? 137.008 136.655 121.740 1.00 70.80  ? 24  GLN L CB  1 
ATOM 38   C CG  . GLN A 1 9   ? 135.608 137.152 122.036 1.00 70.80  ? 24  GLN L CG  1 
ATOM 39   C CD  . GLN A 1 9   ? 134.652 136.020 122.344 1.00 70.80  ? 24  GLN L CD  1 
ATOM 40   O OE1 . GLN A 1 9   ? 135.064 134.874 122.513 1.00 70.80  ? 24  GLN L OE1 1 
ATOM 41   N NE2 . GLN A 1 9   ? 133.366 136.334 122.414 1.00 70.80  ? 24  GLN L NE2 1 
ATOM 42   N N   . SER A 1 10  ? 137.574 139.556 122.455 1.00 76.02  ? 25  SER L N   1 
ATOM 43   C CA  . SER A 1 10  ? 137.964 140.779 123.148 1.00 76.02  ? 25  SER L CA  1 
ATOM 44   C C   . SER A 1 10  ? 137.346 140.674 124.548 1.00 76.02  ? 25  SER L C   1 
ATOM 45   O O   . SER A 1 10  ? 136.653 139.684 124.800 1.00 76.02  ? 25  SER L O   1 
ATOM 46   C CB  . SER A 1 10  ? 137.523 141.981 122.303 1.00 76.02  ? 25  SER L CB  1 
ATOM 47   O OG  . SER A 1 10  ? 137.915 143.229 122.838 1.00 76.02  ? 25  SER L OG  1 
ATOM 48   N N   . PRO A 1 11  ? 137.510 141.671 125.479 1.00 81.32  ? 26  PRO L N   1 
ATOM 49   C CA  . PRO A 1 11  ? 137.803 141.338 126.889 1.00 81.32  ? 26  PRO L CA  1 
ATOM 50   C C   . PRO A 1 11  ? 137.104 140.112 127.458 1.00 81.32  ? 26  PRO L C   1 
ATOM 51   O O   . PRO A 1 11  ? 135.882 139.968 127.349 1.00 81.32  ? 26  PRO L O   1 
ATOM 52   C CB  . PRO A 1 11  ? 137.350 142.598 127.642 1.00 81.32  ? 26  PRO L CB  1 
ATOM 53   C CG  . PRO A 1 11  ? 137.360 143.666 126.629 1.00 81.32  ? 26  PRO L CG  1 
ATOM 54   C CD  . PRO A 1 11  ? 136.828 142.976 125.426 1.00 81.32  ? 26  PRO L CD  1 
ATOM 55   N N   . ALA A 1 12  ? 137.883 139.237 128.100 1.00 82.70  ? 27  ALA L N   1 
ATOM 56   C CA  . ALA A 1 12  ? 137.348 137.965 128.572 1.00 82.70  ? 27  ALA L CA  1 
ATOM 57   C C   . ALA A 1 12  ? 136.515 138.117 129.840 1.00 82.70  ? 27  ALA L C   1 
ATOM 58   O O   . ALA A 1 12  ? 135.537 137.384 130.026 1.00 82.70  ? 27  ALA L O   1 
ATOM 59   C CB  . ALA A 1 12  ? 138.488 136.976 128.806 1.00 82.70  ? 27  ALA L CB  1 
ATOM 60   N N   . SER A 1 13  ? 136.878 139.042 130.727 1.00 86.63  ? 28  SER L N   1 
ATOM 61   C CA  . SER A 1 13  ? 136.209 139.123 132.024 1.00 86.63  ? 28  SER L CA  1 
ATOM 62   C C   . SER A 1 13  ? 135.044 140.110 132.013 1.00 86.63  ? 28  SER L C   1 
ATOM 63   O O   . SER A 1 13  ? 133.906 139.737 132.314 1.00 86.63  ? 28  SER L O   1 
ATOM 64   C CB  . SER A 1 13  ? 137.220 139.501 133.111 1.00 86.63  ? 28  SER L CB  1 
ATOM 65   O OG  . SER A 1 13  ? 136.708 139.214 134.400 1.00 86.63  ? 28  SER L OG  1 
ATOM 66   N N   . LEU A 1 14  ? 135.327 141.380 131.719 1.00 88.76  ? 29  LEU L N   1 
ATOM 67   C CA  . LEU A 1 14  ? 134.316 142.423 131.552 1.00 88.76  ? 29  LEU L CA  1 
ATOM 68   C C   . LEU A 1 14  ? 133.567 142.748 132.842 1.00 88.76  ? 29  LEU L C   1 
ATOM 69   O O   . LEU A 1 14  ? 132.790 143.707 132.875 1.00 88.76  ? 29  LEU L O   1 
ATOM 70   C CB  . LEU A 1 14  ? 133.322 142.031 130.455 1.00 88.76  ? 29  LEU L CB  1 
ATOM 71   C CG  . LEU A 1 14  ? 133.623 142.589 129.064 1.00 88.76  ? 29  LEU L CG  1 
ATOM 72   C CD1 . LEU A 1 14  ? 132.569 142.142 128.066 1.00 88.76  ? 29  LEU L CD1 1 
ATOM 73   C CD2 . LEU A 1 14  ? 133.715 144.104 129.107 1.00 88.76  ? 29  LEU L CD2 1 
ATOM 74   N N   . SER A 1 15  ? 133.811 141.976 133.906 1.00 91.91  ? 30  SER L N   1 
ATOM 75   C CA  . SER A 1 15  ? 133.231 142.203 135.228 1.00 91.91  ? 30  SER L CA  1 
ATOM 76   C C   . SER A 1 15  ? 131.742 142.529 135.174 1.00 91.91  ? 30  SER L C   1 
ATOM 77   O O   . SER A 1 15  ? 130.906 141.622 135.181 1.00 91.91  ? 30  SER L O   1 
ATOM 78   C CB  . SER A 1 15  ? 133.985 143.325 135.944 1.00 91.91  ? 30  SER L CB  1 
ATOM 79   O OG  . SER A 1 15  ? 135.365 143.020 136.045 1.00 91.91  ? 30  SER L OG  1 
ATOM 80   N N   . VAL A 1 16  ? 131.431 143.831 135.124 1.00 93.39  ? 31  VAL L N   1 
ATOM 81   C CA  . VAL A 1 16  ? 130.111 144.461 134.995 1.00 93.39  ? 31  VAL L CA  1 
ATOM 82   C C   . VAL A 1 16  ? 129.032 143.869 135.903 1.00 93.39  ? 31  VAL L C   1 
ATOM 83   O O   . VAL A 1 16  ? 128.738 142.670 135.869 1.00 93.39  ? 31  VAL L O   1 
ATOM 84   C CB  . VAL A 1 16  ? 129.637 144.479 133.523 1.00 93.39  ? 31  VAL L CB  1 
ATOM 85   C CG1 . VAL A 1 16  ? 129.399 143.082 132.952 1.00 93.39  ? 31  VAL L CG1 1 
ATOM 86   C CG2 . VAL A 1 16  ? 128.388 145.335 133.381 1.00 93.39  ? 31  VAL L CG2 1 
ATOM 87   N N   . SER A 1 17  ? 128.412 144.728 136.705 1.00 96.69  ? 32  SER L N   1 
ATOM 88   C CA  . SER A 1 17  ? 127.260 144.354 137.509 1.00 96.69  ? 32  SER L CA  1 
ATOM 89   C C   . SER A 1 17  ? 125.985 144.491 136.682 1.00 96.69  ? 32  SER L C   1 
ATOM 90   O O   . SER A 1 17  ? 125.995 144.994 135.558 1.00 96.69  ? 32  SER L O   1 
ATOM 91   C CB  . SER A 1 17  ? 127.185 145.213 138.772 1.00 96.69  ? 32  SER L CB  1 
ATOM 92   O OG  . SER A 1 17  ? 128.431 145.232 139.449 1.00 96.69  ? 32  SER L OG  1 
ATOM 93   N N   . VAL A 1 18  ? 124.870 144.048 137.254 1.00 94.56  ? 33  VAL L N   1 
ATOM 94   C CA  . VAL A 1 18  ? 123.599 144.003 136.511 1.00 94.56  ? 33  VAL L CA  1 
ATOM 95   C C   . VAL A 1 18  ? 122.942 145.370 136.682 1.00 94.56  ? 33  VAL L C   1 
ATOM 96   O O   . VAL A 1 18  ? 122.011 145.577 137.463 1.00 94.56  ? 33  VAL L O   1 
ATOM 97   C CB  . VAL A 1 18  ? 122.716 142.822 136.952 1.00 94.56  ? 33  VAL L CB  1 
ATOM 98   C CG1 . VAL A 1 18  ? 122.336 142.901 138.432 1.00 94.56  ? 33  VAL L CG1 1 
ATOM 99   C CG2 . VAL A 1 18  ? 121.460 142.756 136.100 1.00 94.56  ? 33  VAL L CG2 1 
ATOM 100  N N   . GLY A 1 19  ? 123.440 146.335 135.914 1.00 98.74  ? 34  GLY L N   1 
ATOM 101  C CA  . GLY A 1 19  ? 122.757 147.605 135.787 1.00 98.74  ? 34  GLY L CA  1 
ATOM 102  C C   . GLY A 1 19  ? 122.966 148.313 134.465 1.00 98.74  ? 34  GLY L C   1 
ATOM 103  O O   . GLY A 1 19  ? 122.495 149.441 134.290 1.00 98.74  ? 34  GLY L O   1 
ATOM 104  N N   . GLU A 1 20  ? 123.659 147.677 133.521 1.00 99.29  ? 35  GLU L N   1 
ATOM 105  C CA  . GLU A 1 20  ? 124.164 148.389 132.356 1.00 99.29  ? 35  GLU L CA  1 
ATOM 106  C C   . GLU A 1 20  ? 124.209 147.479 131.138 1.00 99.29  ? 35  GLU L C   1 
ATOM 107  O O   . GLU A 1 20  ? 124.220 146.251 131.255 1.00 99.29  ? 35  GLU L O   1 
ATOM 108  C CB  . GLU A 1 20  ? 125.573 148.953 132.608 1.00 99.29  ? 35  GLU L CB  1 
ATOM 109  C CG  . GLU A 1 20  ? 125.644 150.073 133.636 1.00 99.29  ? 35  GLU L CG  1 
ATOM 110  C CD  . GLU A 1 20  ? 127.059 150.565 133.867 1.00 99.29  ? 35  GLU L CD  1 
ATOM 111  O OE1 . GLU A 1 20  ? 128.001 149.947 133.327 1.00 99.29  ? 35  GLU L OE1 1 
ATOM 112  O OE2 . GLU A 1 20  ? 127.231 151.571 134.586 1.00 99.29  ? 35  GLU L OE2 1 
ATOM 113  N N   . THR A 1 21  ? 124.237 148.106 129.965 1.00 92.06  ? 36  THR L N   1 
ATOM 114  C CA  . THR A 1 21  ? 124.493 147.385 128.727 1.00 92.06  ? 36  THR L CA  1 
ATOM 115  C C   . THR A 1 21  ? 125.944 146.927 128.683 1.00 92.06  ? 36  THR L C   1 
ATOM 116  O O   . THR A 1 21  ? 126.835 147.583 129.230 1.00 92.06  ? 36  THR L O   1 
ATOM 117  C CB  . THR A 1 21  ? 124.199 148.270 127.517 1.00 92.06  ? 36  THR L CB  1 
ATOM 118  O OG1 . THR A 1 21  ? 125.168 149.324 127.451 1.00 92.06  ? 36  THR L OG1 1 
ATOM 119  C CG2 . THR A 1 21  ? 122.816 148.882 127.625 1.00 92.06  ? 36  THR L CG2 1 
ATOM 120  N N   . VAL A 1 22  ? 126.183 145.795 128.028 1.00 83.37  ? 37  VAL L N   1 
ATOM 121  C CA  . VAL A 1 22  ? 127.528 145.265 127.845 1.00 83.37  ? 37  VAL L CA  1 
ATOM 122  C C   . VAL A 1 22  ? 127.731 144.968 126.366 1.00 83.37  ? 37  VAL L C   1 
ATOM 123  O O   . VAL A 1 22  ? 126.839 144.422 125.707 1.00 83.37  ? 37  VAL L O   1 
ATOM 124  C CB  . VAL A 1 22  ? 127.776 144.013 128.712 1.00 83.37  ? 37  VAL L CB  1 
ATOM 125  C CG1 . VAL A 1 22  ? 126.881 142.856 128.289 1.00 83.37  ? 37  VAL L CG1 1 
ATOM 126  C CG2 . VAL A 1 22  ? 129.241 143.616 128.663 1.00 83.37  ? 37  VAL L CG2 1 
ATOM 127  N N   . THR A 1 23  ? 128.886 145.363 125.837 1.00 77.34  ? 38  THR L N   1 
ATOM 128  C CA  . THR A 1 23  ? 129.208 145.186 124.430 1.00 77.34  ? 38  THR L CA  1 
ATOM 129  C C   . THR A 1 23  ? 130.574 144.529 124.308 1.00 77.34  ? 38  THR L C   1 
ATOM 130  O O   . THR A 1 23  ? 131.515 144.900 125.015 1.00 77.34  ? 38  THR L O   1 
ATOM 131  C CB  . THR A 1 23  ? 129.199 146.527 123.683 1.00 77.34  ? 38  THR L CB  1 
ATOM 132  O OG1 . THR A 1 23  ? 127.893 147.111 123.764 1.00 77.34  ? 38  THR L OG1 1 
ATOM 133  C CG2 . THR A 1 23  ? 129.567 146.332 122.220 1.00 77.34  ? 38  THR L CG2 1 
ATOM 134  N N   . LEU A 1 24  ? 130.679 143.553 123.408 1.00 72.60  ? 39  LEU L N   1 
ATOM 135  C CA  . LEU A 1 24  ? 131.916 142.811 123.212 1.00 72.60  ? 39  LEU L CA  1 
ATOM 136  C C   . LEU A 1 24  ? 132.099 142.540 121.726 1.00 72.60  ? 39  LEU L C   1 
ATOM 137  O O   . LEU A 1 24  ? 131.156 142.631 120.941 1.00 72.60  ? 39  LEU L O   1 
ATOM 138  C CB  . LEU A 1 24  ? 131.910 141.520 124.046 1.00 72.60  ? 39  LEU L CB  1 
ATOM 139  C CG  . LEU A 1 24  ? 130.839 140.457 123.790 1.00 72.60  ? 39  LEU L CG  1 
ATOM 140  C CD1 . LEU A 1 24  ? 131.203 139.538 122.637 1.00 72.60  ? 39  LEU L CD1 1 
ATOM 141  C CD2 . LEU A 1 24  ? 130.567 139.659 125.056 1.00 72.60  ? 39  LEU L CD2 1 
ATOM 142  N N   . THR A 1 25  ? 133.335 142.232 121.335 1.00 71.66  ? 40  THR L N   1 
ATOM 143  C CA  . THR A 1 25  ? 133.667 142.023 119.933 1.00 71.66  ? 40  THR L CA  1 
ATOM 144  C C   . THR A 1 25  ? 134.387 140.694 119.756 1.00 71.66  ? 40  THR L C   1 
ATOM 145  O O   . THR A 1 25  ? 134.991 140.158 120.688 1.00 71.66  ? 40  THR L O   1 
ATOM 146  C CB  . THR A 1 25  ? 134.543 143.152 119.368 1.00 71.66  ? 40  THR L CB  1 
ATOM 147  O OG1 . THR A 1 25  ? 135.907 142.938 119.748 1.00 71.66  ? 40  THR L OG1 1 
ATOM 148  C CG2 . THR A 1 25  ? 134.086 144.506 119.881 1.00 71.66  ? 40  THR L CG2 1 
ATOM 149  N N   . CYS A 1 26  ? 134.309 140.167 118.532 1.00 70.40  ? 41  CYS L N   1 
ATOM 150  C CA  . CYS A 1 26  ? 134.976 138.916 118.153 1.00 70.40  ? 41  CYS L CA  1 
ATOM 151  C C   . CYS A 1 26  ? 135.633 139.152 116.795 1.00 70.40  ? 41  CYS L C   1 
ATOM 152  O O   . CYS A 1 26  ? 135.002 138.980 115.749 1.00 70.40  ? 41  CYS L O   1 
ATOM 153  C CB  . CYS A 1 26  ? 133.995 137.751 118.119 1.00 70.40  ? 41  CYS L CB  1 
ATOM 154  S SG  . CYS A 1 26  ? 134.614 136.232 117.356 1.00 70.40  ? 41  CYS L SG  1 
ATOM 155  N N   . ARG A 1 27  ? 136.902 139.549 116.822 1.00 72.65  ? 42  ARG L N   1 
ATOM 156  C CA  . ARG A 1 27  ? 137.624 139.862 115.598 1.00 72.65  ? 42  ARG L CA  1 
ATOM 157  C C   . ARG A 1 27  ? 137.879 138.612 114.766 1.00 72.65  ? 42  ARG L C   1 
ATOM 158  O O   . ARG A 1 27  ? 137.990 137.500 115.288 1.00 72.65  ? 42  ARG L O   1 
ATOM 159  C CB  . ARG A 1 27  ? 138.958 140.528 115.918 1.00 72.65  ? 42  ARG L CB  1 
ATOM 160  C CG  . ARG A 1 27  ? 138.854 141.861 116.623 1.00 72.65  ? 42  ARG L CG  1 
ATOM 161  C CD  . ARG A 1 27  ? 140.108 142.699 116.399 1.00 72.65  ? 42  ARG L CD  1 
ATOM 162  N NE  . ARG A 1 27  ? 141.335 141.913 116.486 1.00 72.65  ? 42  ARG L NE  1 
ATOM 163  C CZ  . ARG A 1 27  ? 142.048 141.507 115.442 1.00 72.65  ? 42  ARG L CZ  1 
ATOM 164  N NH1 . ARG A 1 27  ? 141.683 141.792 114.203 1.00 72.65  ? 42  ARG L NH1 1 
ATOM 165  N NH2 . ARG A 1 27  ? 143.152 140.795 115.648 1.00 72.65  ? 42  ARG L NH2 1 
ATOM 166  N N   . ALA A 1 28  ? 137.982 138.811 113.456 1.00 69.28  ? 43  ALA L N   1 
ATOM 167  C CA  . ALA A 1 28  ? 138.332 137.761 112.511 1.00 69.28  ? 43  ALA L CA  1 
ATOM 168  C C   . ALA A 1 28  ? 139.646 138.122 111.837 1.00 69.28  ? 43  ALA L C   1 
ATOM 169  O O   . ALA A 1 28  ? 139.971 139.303 111.684 1.00 69.28  ? 43  ALA L O   1 
ATOM 170  C CB  . ALA A 1 28  ? 137.236 137.565 111.464 1.00 69.28  ? 43  ALA L CB  1 
ATOM 171  N N   . SER A 1 29  ? 140.404 137.103 111.435 1.00 65.92  ? 44  SER L N   1 
ATOM 172  C CA  . SER A 1 29  ? 141.760 137.348 110.960 1.00 65.92  ? 44  SER L CA  1 
ATOM 173  C C   . SER A 1 29  ? 141.808 137.668 109.470 1.00 65.92  ? 44  SER L C   1 
ATOM 174  O O   . SER A 1 29  ? 142.619 138.496 109.042 1.00 65.92  ? 44  SER L O   1 
ATOM 175  C CB  . SER A 1 29  ? 142.648 136.144 111.268 1.00 65.92  ? 44  SER L CB  1 
ATOM 176  O OG  . SER A 1 29  ? 142.492 135.133 110.289 1.00 65.92  ? 44  SER L OG  1 
ATOM 177  N N   . GLU A 1 30  ? 140.965 137.029 108.661 1.00 67.73  ? 45  GLU L N   1 
ATOM 178  C CA  . GLU A 1 30  ? 141.097 137.098 107.207 1.00 67.73  ? 45  GLU L CA  1 
ATOM 179  C C   . GLU A 1 30  ? 139.753 137.360 106.539 1.00 67.73  ? 45  GLU L C   1 
ATOM 180  O O   . GLU A 1 30  ? 139.414 136.754 105.521 1.00 67.73  ? 45  GLU L O   1 
ATOM 181  C CB  . GLU A 1 30  ? 141.718 135.816 106.661 1.00 67.73  ? 45  GLU L CB  1 
ATOM 182  C CG  . GLU A 1 30  ? 143.163 135.600 107.070 1.00 67.73  ? 45  GLU L CG  1 
ATOM 183  C CD  . GLU A 1 30  ? 143.735 134.308 106.523 1.00 67.73  ? 45  GLU L CD  1 
ATOM 184  O OE1 . GLU A 1 30  ? 142.967 133.523 105.929 1.00 67.73  ? 45  GLU L OE1 1 
ATOM 185  O OE2 . GLU A 1 30  ? 144.950 134.074 106.692 1.00 67.73  ? 45  GLU L OE2 1 
ATOM 186  N N   . ASN A 1 31  ? 138.972 138.281 107.103 1.00 60.62  ? 46  ASN L N   1 
ATOM 187  C CA  . ASN A 1 31  ? 137.754 138.796 106.473 1.00 60.62  ? 46  ASN L CA  1 
ATOM 188  C C   . ASN A 1 31  ? 136.758 137.670 106.174 1.00 60.62  ? 46  ASN L C   1 
ATOM 189  O O   . ASN A 1 31  ? 136.432 137.372 105.024 1.00 60.62  ? 46  ASN L O   1 
ATOM 190  C CB  . ASN A 1 31  ? 138.095 139.578 105.197 1.00 60.62  ? 46  ASN L CB  1 
ATOM 191  C CG  . ASN A 1 31  ? 136.880 140.248 104.570 1.00 60.62  ? 46  ASN L CG  1 
ATOM 192  O OD1 . ASN A 1 31  ? 135.769 140.173 105.093 1.00 60.62  ? 46  ASN L OD1 1 
ATOM 193  N ND2 . ASN A 1 31  ? 137.090 140.904 103.436 1.00 60.62  ? 46  ASN L ND2 1 
ATOM 194  N N   . ILE A 1 32  ? 136.282 137.043 107.248 1.00 57.57  ? 47  ILE L N   1 
ATOM 195  C CA  . ILE A 1 32  ? 135.118 136.178 107.119 1.00 57.57  ? 47  ILE L CA  1 
ATOM 196  C C   . ILE A 1 32  ? 133.913 137.047 106.797 1.00 57.57  ? 47  ILE L C   1 
ATOM 197  O O   . ILE A 1 32  ? 133.767 138.155 107.328 1.00 57.57  ? 47  ILE L O   1 
ATOM 198  C CB  . ILE A 1 32  ? 134.895 135.354 108.396 1.00 57.57  ? 47  ILE L CB  1 
ATOM 199  C CG1 . ILE A 1 32  ? 134.392 136.234 109.537 1.00 57.57  ? 47  ILE L CG1 1 
ATOM 200  C CG2 . ILE A 1 32  ? 136.177 134.665 108.808 1.00 57.57  ? 47  ILE L CG2 1 
ATOM 201  C CD1 . ILE A 1 32  ? 133.754 135.465 110.658 1.00 57.57  ? 47  ILE L CD1 1 
ATOM 202  N N   . TYR A 1 33  ? 133.061 136.575 105.897 1.00 51.84  ? 48  TYR L N   1 
ATOM 203  C CA  . TYR A 1 33  ? 131.883 137.360 105.582 1.00 51.84  ? 48  TYR L CA  1 
ATOM 204  C C   . TYR A 1 33  ? 130.835 137.177 106.676 1.00 51.84  ? 48  TYR L C   1 
ATOM 205  O O   . TYR A 1 33  ? 131.055 136.496 107.680 1.00 51.84  ? 48  TYR L O   1 
ATOM 206  C CB  . TYR A 1 33  ? 131.343 136.992 104.204 1.00 51.84  ? 48  TYR L CB  1 
ATOM 207  C CG  . TYR A 1 33  ? 132.227 137.504 103.090 1.00 51.84  ? 48  TYR L CG  1 
ATOM 208  C CD1 . TYR A 1 33  ? 133.471 136.942 102.852 1.00 51.84  ? 48  TYR L CD1 1 
ATOM 209  C CD2 . TYR A 1 33  ? 131.832 138.571 102.300 1.00 51.84  ? 48  TYR L CD2 1 
ATOM 210  C CE1 . TYR A 1 33  ? 134.287 137.412 101.849 1.00 51.84  ? 48  TYR L CE1 1 
ATOM 211  C CE2 . TYR A 1 33  ? 132.643 139.049 101.292 1.00 51.84  ? 48  TYR L CE2 1 
ATOM 212  C CZ  . TYR A 1 33  ? 133.870 138.464 101.072 1.00 51.84  ? 48  TYR L CZ  1 
ATOM 213  O OH  . TYR A 1 33  ? 134.684 138.933 100.070 1.00 51.84  ? 48  TYR L OH  1 
ATOM 214  N N   . SER A 1 34  ? 129.680 137.806 106.481 1.00 55.17  ? 49  SER L N   1 
ATOM 215  C CA  . SER A 1 34  ? 128.688 137.914 107.547 1.00 55.17  ? 49  SER L CA  1 
ATOM 216  C C   . SER A 1 34  ? 128.011 136.562 107.752 1.00 55.17  ? 49  SER L C   1 
ATOM 217  O O   . SER A 1 34  ? 126.849 136.349 107.402 1.00 55.17  ? 49  SER L O   1 
ATOM 218  C CB  . SER A 1 34  ? 127.672 139.000 107.221 1.00 55.17  ? 49  SER L CB  1 
ATOM 219  O OG  . SER A 1 34  ? 128.292 140.273 107.166 1.00 55.17  ? 49  SER L OG  1 
ATOM 220  N N   . ASN A 1 35  ? 128.763 135.627 108.338 1.00 52.65  ? 50  ASN L N   1 
ATOM 221  C CA  . ASN A 1 35  ? 128.190 134.352 108.773 1.00 52.65  ? 50  ASN L CA  1 
ATOM 222  C C   . ASN A 1 35  ? 129.015 133.839 109.951 1.00 52.65  ? 50  ASN L C   1 
ATOM 223  O O   . ASN A 1 35  ? 130.085 133.255 109.762 1.00 52.65  ? 50  ASN L O   1 
ATOM 224  C CB  . ASN A 1 35  ? 128.126 133.340 107.634 1.00 52.65  ? 50  ASN L CB  1 
ATOM 225  C CG  . ASN A 1 35  ? 129.390 133.295 106.809 1.00 52.65  ? 50  ASN L CG  1 
ATOM 226  O OD1 . ASN A 1 35  ? 130.394 133.913 107.150 1.00 52.65  ? 50  ASN L OD1 1 
ATOM 227  N ND2 . ASN A 1 35  ? 129.341 132.567 105.701 1.00 52.65  ? 50  ASN L ND2 1 
ATOM 228  N N   . LEU A 1 36  ? 128.505 134.067 111.158 1.00 52.63  ? 51  LEU L N   1 
ATOM 229  C CA  . LEU A 1 36  ? 129.117 133.564 112.378 1.00 52.63  ? 51  LEU L CA  1 
ATOM 230  C C   . LEU A 1 36  ? 128.028 133.430 113.431 1.00 52.63  ? 51  LEU L C   1 
ATOM 231  O O   . LEU A 1 36  ? 126.959 134.033 113.320 1.00 52.63  ? 51  LEU L O   1 
ATOM 232  C CB  . LEU A 1 36  ? 130.244 134.476 112.875 1.00 52.63  ? 51  LEU L CB  1 
ATOM 233  C CG  . LEU A 1 36  ? 129.884 135.711 113.698 1.00 52.63  ? 51  LEU L CG  1 
ATOM 234  C CD1 . LEU A 1 36  ? 131.147 136.355 114.231 1.00 52.63  ? 51  LEU L CD1 1 
ATOM 235  C CD2 . LEU A 1 36  ? 129.087 136.707 112.880 1.00 52.63  ? 51  LEU L CD2 1 
ATOM 236  N N   . ALA A 1 37  ? 128.313 132.635 114.455 1.00 51.96  ? 52  ALA L N   1 
ATOM 237  C CA  . ALA A 1 37  ? 127.351 132.343 115.505 1.00 51.96  ? 52  ALA L CA  1 
ATOM 238  C C   . ALA A 1 37  ? 127.827 132.918 116.832 1.00 51.96  ? 52  ALA L C   1 
ATOM 239  O O   . ALA A 1 37  ? 128.987 133.301 116.994 1.00 51.96  ? 52  ALA L O   1 
ATOM 240  C CB  . ALA A 1 37  ? 127.115 130.835 115.630 1.00 51.96  ? 52  ALA L CB  1 
ATOM 241  N N   . TRP A 1 38  ? 126.905 132.964 117.795 1.00 56.83  ? 53  TRP L N   1 
ATOM 242  C CA  . TRP A 1 38  ? 127.160 133.572 119.093 1.00 56.83  ? 53  TRP L CA  1 
ATOM 243  C C   . TRP A 1 38  ? 126.726 132.721 120.276 1.00 56.83  ? 53  TRP L C   1 
ATOM 244  O O   . TRP A 1 38  ? 125.987 133.221 121.129 1.00 56.83  ? 53  TRP L O   1 
ATOM 245  C CB  . TRP A 1 38  ? 126.479 134.944 119.184 1.00 56.83  ? 53  TRP L CB  1 
ATOM 246  C CG  . TRP A 1 38  ? 127.287 136.019 118.545 1.00 56.83  ? 53  TRP L CG  1 
ATOM 247  C CD1 . TRP A 1 38  ? 127.010 136.675 117.384 1.00 56.83  ? 53  TRP L CD1 1 
ATOM 248  C CD2 . TRP A 1 38  ? 128.521 136.556 119.026 1.00 56.83  ? 53  TRP L CD2 1 
ATOM 249  N NE1 . TRP A 1 38  ? 127.993 137.593 117.115 1.00 56.83  ? 53  TRP L NE1 1 
ATOM 250  C CE2 . TRP A 1 38  ? 128.933 137.538 118.110 1.00 56.83  ? 53  TRP L CE2 1 
ATOM 251  C CE3 . TRP A 1 38  ? 129.315 136.302 120.146 1.00 56.83  ? 53  TRP L CE3 1 
ATOM 252  C CZ2 . TRP A 1 38  ? 130.103 138.267 118.280 1.00 56.83  ? 53  TRP L CZ2 1 
ATOM 253  C CZ3 . TRP A 1 38  ? 130.474 137.025 120.310 1.00 56.83  ? 53  TRP L CZ3 1 
ATOM 254  C CH2 . TRP A 1 38  ? 130.856 137.996 119.386 1.00 56.83  ? 53  TRP L CH2 1 
ATOM 255  N N   . TYR A 1 39  ? 127.141 131.458 120.339 1.00 55.34  ? 54  TYR L N   1 
ATOM 256  C CA  . TYR A 1 39  ? 126.746 130.495 121.361 1.00 55.34  ? 54  TYR L CA  1 
ATOM 257  C C   . TYR A 1 39  ? 126.830 131.038 122.783 1.00 55.34  ? 54  TYR L C   1 
ATOM 258  O O   . TYR A 1 39  ? 127.713 131.840 123.104 1.00 55.34  ? 54  TYR L O   1 
ATOM 259  C CB  . TYR A 1 39  ? 127.624 129.253 121.235 1.00 55.34  ? 54  TYR L CB  1 
ATOM 260  C CG  . TYR A 1 39  ? 127.622 128.676 119.845 1.00 55.34  ? 54  TYR L CG  1 
ATOM 261  C CD1 . TYR A 1 39  ? 126.435 128.382 119.198 1.00 55.34  ? 54  TYR L CD1 1 
ATOM 262  C CD2 . TYR A 1 39  ? 128.807 128.466 119.163 1.00 55.34  ? 54  TYR L CD2 1 
ATOM 263  C CE1 . TYR A 1 39  ? 126.431 127.865 117.924 1.00 55.34  ? 54  TYR L CE1 1 
ATOM 264  C CE2 . TYR A 1 39  ? 128.811 127.955 117.889 1.00 55.34  ? 54  TYR L CE2 1 
ATOM 265  C CZ  . TYR A 1 39  ? 127.621 127.658 117.272 1.00 55.34  ? 54  TYR L CZ  1 
ATOM 266  O OH  . TYR A 1 39  ? 127.619 127.145 115.998 1.00 55.34  ? 54  TYR L OH  1 
ATOM 267  N N   . HIS A 1 40  ? 125.908 130.602 123.636 1.00 65.41  ? 55  HIS L N   1 
ATOM 268  C CA  . HIS A 1 40  ? 125.883 130.956 125.049 1.00 65.41  ? 55  HIS L CA  1 
ATOM 269  C C   . HIS A 1 40  ? 125.672 129.696 125.875 1.00 65.41  ? 55  HIS L C   1 
ATOM 270  O O   . HIS A 1 40  ? 124.787 128.892 125.567 1.00 65.41  ? 55  HIS L O   1 
ATOM 271  C CB  . HIS A 1 40  ? 124.776 131.968 125.333 1.00 65.41  ? 55  HIS L CB  1 
ATOM 272  C CG  . HIS A 1 40  ? 124.556 132.235 126.789 1.00 65.41  ? 55  HIS L CG  1 
ATOM 273  N ND1 . HIS A 1 40  ? 125.233 133.216 127.478 1.00 65.41  ? 55  HIS L ND1 1 
ATOM 274  C CD2 . HIS A 1 40  ? 123.716 131.661 127.682 1.00 65.41  ? 55  HIS L CD2 1 
ATOM 275  C CE1 . HIS A 1 40  ? 124.829 133.228 128.735 1.00 65.41  ? 55  HIS L CE1 1 
ATOM 276  N NE2 . HIS A 1 40  ? 123.908 132.293 128.886 1.00 65.41  ? 55  HIS L NE2 1 
ATOM 277  N N   . GLN A 1 41  ? 126.474 129.524 126.922 1.00 66.66  ? 56  GLN L N   1 
ATOM 278  C CA  . GLN A 1 41  ? 126.340 128.386 127.819 1.00 66.66  ? 56  GLN L CA  1 
ATOM 279  C C   . GLN A 1 41  ? 126.404 128.849 129.265 1.00 66.66  ? 56  GLN L C   1 
ATOM 280  O O   . GLN A 1 41  ? 127.213 129.712 129.612 1.00 66.66  ? 56  GLN L O   1 
ATOM 281  C CB  . GLN A 1 41  ? 127.417 127.330 127.553 1.00 66.66  ? 56  GLN L CB  1 
ATOM 282  C CG  . GLN A 1 41  ? 128.840 127.734 127.871 1.00 66.66  ? 56  GLN L CG  1 
ATOM 283  C CD  . GLN A 1 41  ? 129.718 126.531 128.154 1.00 66.66  ? 56  GLN L CD  1 
ATOM 284  O OE1 . GLN A 1 41  ? 129.225 125.462 128.510 1.00 66.66  ? 56  GLN L OE1 1 
ATOM 285  N NE2 . GLN A 1 41  ? 131.024 126.696 127.992 1.00 66.66  ? 56  GLN L NE2 1 
ATOM 286  N N   . LYS A 1 42  ? 125.532 128.294 130.096 1.00 73.75  ? 57  LYS L N   1 
ATOM 287  C CA  . LYS A 1 42  ? 125.648 128.431 131.537 1.00 73.75  ? 57  LYS L CA  1 
ATOM 288  C C   . LYS A 1 42  ? 126.340 127.190 132.076 1.00 73.75  ? 57  LYS L C   1 
ATOM 289  O O   . LYS A 1 42  ? 126.037 126.071 131.654 1.00 73.75  ? 57  LYS L O   1 
ATOM 290  C CB  . LYS A 1 42  ? 124.273 128.608 132.179 1.00 73.75  ? 57  LYS L CB  1 
ATOM 291  C CG  . LYS A 1 42  ? 123.687 129.997 131.987 1.00 73.75  ? 57  LYS L CG  1 
ATOM 292  C CD  . LYS A 1 42  ? 122.251 130.067 132.475 1.00 73.75  ? 57  LYS L CD  1 
ATOM 293  C CE  . LYS A 1 42  ? 121.424 128.917 131.926 1.00 73.75  ? 57  LYS L CE  1 
ATOM 294  N NZ  . LYS A 1 42  ? 119.970 129.235 131.918 1.00 73.75  ? 57  LYS L NZ  1 
ATOM 295  N N   . GLN A 1 43  ? 127.286 127.393 132.992 1.00 75.31  ? 58  GLN L N   1 
ATOM 296  C CA  . GLN A 1 43  ? 128.148 126.298 133.417 1.00 75.31  ? 58  GLN L CA  1 
ATOM 297  C C   . GLN A 1 43  ? 127.325 125.133 133.956 1.00 75.31  ? 58  GLN L C   1 
ATOM 298  O O   . GLN A 1 43  ? 126.358 125.316 134.701 1.00 75.31  ? 58  GLN L O   1 
ATOM 299  C CB  . GLN A 1 43  ? 129.156 126.789 134.462 1.00 75.31  ? 58  GLN L CB  1 
ATOM 300  C CG  . GLN A 1 43  ? 128.648 126.850 135.893 1.00 75.31  ? 58  GLN L CG  1 
ATOM 301  C CD  . GLN A 1 43  ? 129.425 127.835 136.740 1.00 75.31  ? 58  GLN L CD  1 
ATOM 302  O OE1 . GLN A 1 43  ? 130.357 128.482 136.262 1.00 75.31  ? 58  GLN L OE1 1 
ATOM 303  N NE2 . GLN A 1 43  ? 129.044 127.957 138.007 1.00 75.31  ? 58  GLN L NE2 1 
ATOM 304  N N   . GLY A 1 44  ? 127.691 123.926 133.530 1.00 72.40  ? 59  GLY L N   1 
ATOM 305  C CA  . GLY A 1 44  ? 126.987 122.723 133.913 1.00 72.40  ? 59  GLY L CA  1 
ATOM 306  C C   . GLY A 1 44  ? 126.035 122.161 132.878 1.00 72.40  ? 59  GLY L C   1 
ATOM 307  O O   . GLY A 1 44  ? 125.605 121.011 133.026 1.00 72.40  ? 59  GLY L O   1 
ATOM 308  N N   . ILE A 1 45  ? 125.689 122.924 131.838 1.00 67.92  ? 60  ILE L N   1 
ATOM 309  C CA  . ILE A 1 45  ? 124.767 122.459 130.808 1.00 67.92  ? 60  ILE L CA  1 
ATOM 310  C C   . ILE A 1 45  ? 125.327 122.807 129.436 1.00 67.92  ? 60  ILE L C   1 
ATOM 311  O O   . ILE A 1 45  ? 126.318 123.529 129.306 1.00 67.92  ? 60  ILE L O   1 
ATOM 312  C CB  . ILE A 1 45  ? 123.346 123.051 130.969 1.00 67.92  ? 60  ILE L CB  1 
ATOM 313  C CG1 . ILE A 1 45  ? 123.376 124.573 130.835 1.00 67.92  ? 60  ILE L CG1 1 
ATOM 314  C CG2 . ILE A 1 45  ? 122.736 122.635 132.297 1.00 67.92  ? 60  ILE L CG2 1 
ATOM 315  C CD1 . ILE A 1 45  ? 122.003 125.203 130.750 1.00 67.92  ? 60  ILE L CD1 1 
ATOM 316  N N   . SER A 1 46  ? 124.673 122.280 128.403 1.00 61.17  ? 61  SER L N   1 
ATOM 317  C CA  . SER A 1 46  ? 125.139 122.446 127.036 1.00 61.17  ? 61  SER L CA  1 
ATOM 318  C C   . SER A 1 46  ? 124.927 123.883 126.560 1.00 61.17  ? 61  SER L C   1 
ATOM 319  O O   . SER A 1 46  ? 124.043 124.587 127.054 1.00 61.17  ? 61  SER L O   1 
ATOM 320  C CB  . SER A 1 46  ? 124.404 121.479 126.114 1.00 61.17  ? 61  SER L CB  1 
ATOM 321  O OG  . SER A 1 46  ? 123.002 121.602 126.272 1.00 61.17  ? 61  SER L OG  1 
ATOM 322  N N   . PRO A 1 47  ? 125.727 124.344 125.601 1.00 57.82  ? 62  PRO L N   1 
ATOM 323  C CA  . PRO A 1 47  ? 125.559 125.706 125.088 1.00 57.82  ? 62  PRO L CA  1 
ATOM 324  C C   . PRO A 1 47  ? 124.249 125.884 124.337 1.00 57.82  ? 62  PRO L C   1 
ATOM 325  O O   . PRO A 1 47  ? 123.529 124.931 124.038 1.00 57.82  ? 62  PRO L O   1 
ATOM 326  C CB  . PRO A 1 47  ? 126.759 125.883 124.152 1.00 57.82  ? 62  PRO L CB  1 
ATOM 327  C CG  . PRO A 1 47  ? 127.767 124.914 124.649 1.00 57.82  ? 62  PRO L CG  1 
ATOM 328  C CD  . PRO A 1 47  ? 126.979 123.733 125.128 1.00 57.82  ? 62  PRO L CD  1 
ATOM 329  N N   . GLN A 1 48  ? 123.947 127.146 124.038 1.00 59.48  ? 63  GLN L N   1 
ATOM 330  C CA  . GLN A 1 48  ? 122.737 127.511 123.319 1.00 59.48  ? 63  GLN L CA  1 
ATOM 331  C C   . GLN A 1 48  ? 123.061 128.604 122.312 1.00 59.48  ? 63  GLN L C   1 
ATOM 332  O O   . GLN A 1 48  ? 123.968 129.412 122.521 1.00 59.48  ? 63  GLN L O   1 
ATOM 333  C CB  . GLN A 1 48  ? 121.637 127.984 124.274 1.00 59.48  ? 63  GLN L CB  1 
ATOM 334  C CG  . GLN A 1 48  ? 120.232 127.724 123.771 1.00 59.48  ? 63  GLN L CG  1 
ATOM 335  C CD  . GLN A 1 48  ? 119.194 127.856 124.864 1.00 59.48  ? 63  GLN L CD  1 
ATOM 336  O OE1 . GLN A 1 48  ? 119.523 127.867 126.049 1.00 59.48  ? 63  GLN L OE1 1 
ATOM 337  N NE2 . GLN A 1 48  ? 117.930 127.960 124.470 1.00 59.48  ? 63  GLN L NE2 1 
ATOM 338  N N   . LEU A 1 49  ? 122.305 128.622 121.219 1.00 56.65  ? 64  LEU L N   1 
ATOM 339  C CA  . LEU A 1 49  ? 122.533 129.581 120.148 1.00 56.65  ? 64  LEU L CA  1 
ATOM 340  C C   . LEU A 1 49  ? 121.687 130.831 120.350 1.00 56.65  ? 64  LEU L C   1 
ATOM 341  O O   . LEU A 1 49  ? 120.493 130.748 120.651 1.00 56.65  ? 64  LEU L O   1 
ATOM 342  C CB  . LEU A 1 49  ? 122.217 128.944 118.796 1.00 56.65  ? 64  LEU L CB  1 
ATOM 343  C CG  . LEU A 1 49  ? 122.333 129.805 117.540 1.00 56.65  ? 64  LEU L CG  1 
ATOM 344  C CD1 . LEU A 1 49  ? 123.773 129.944 117.104 1.00 56.65  ? 64  LEU L CD1 1 
ATOM 345  C CD2 . LEU A 1 49  ? 121.498 129.198 116.430 1.00 56.65  ? 64  LEU L CD2 1 
ATOM 346  N N   . LEU A 1 50  ? 122.313 131.997 120.180 1.00 60.69  ? 65  LEU L N   1 
ATOM 347  C CA  . LEU A 1 50  ? 121.638 133.278 120.344 1.00 60.69  ? 65  LEU L CA  1 
ATOM 348  C C   . LEU A 1 50  ? 121.522 134.040 119.030 1.00 60.69  ? 65  LEU L C   1 
ATOM 349  O O   . LEU A 1 50  ? 120.418 134.404 118.618 1.00 60.69  ? 65  LEU L O   1 
ATOM 350  C CB  . LEU A 1 50  ? 122.377 134.130 121.384 1.00 60.69  ? 65  LEU L CB  1 
ATOM 351  C CG  . LEU A 1 50  ? 122.503 133.562 122.796 1.00 60.69  ? 65  LEU L CG  1 
ATOM 352  C CD1 . LEU A 1 50  ? 122.997 134.639 123.744 1.00 60.69  ? 65  LEU L CD1 1 
ATOM 353  C CD2 . LEU A 1 50  ? 121.177 132.996 123.270 1.00 60.69  ? 65  LEU L CD2 1 
ATOM 354  N N   . VAL A 1 51  ? 122.641 134.291 118.357 1.00 58.63  ? 66  VAL L N   1 
ATOM 355  C CA  . VAL A 1 51  ? 122.669 134.980 117.073 1.00 58.63  ? 66  VAL L CA  1 
ATOM 356  C C   . VAL A 1 51  ? 123.281 134.031 116.056 1.00 58.63  ? 66  VAL L C   1 
ATOM 357  O O   . VAL A 1 51  ? 124.384 133.516 116.270 1.00 58.63  ? 66  VAL L O   1 
ATOM 358  C CB  . VAL A 1 51  ? 123.469 136.291 117.152 1.00 58.63  ? 66  VAL L CB  1 
ATOM 359  C CG1 . VAL A 1 51  ? 123.704 136.849 115.764 1.00 58.63  ? 66  VAL L CG1 1 
ATOM 360  C CG2 . VAL A 1 51  ? 122.741 137.299 118.022 1.00 58.63  ? 66  VAL L CG2 1 
ATOM 361  N N   . TYR A 1 52  ? 122.571 133.796 114.953 1.00 56.85  ? 67  TYR L N   1 
ATOM 362  C CA  . TYR A 1 52  ? 122.941 132.723 114.044 1.00 56.85  ? 67  TYR L CA  1 
ATOM 363  C C   . TYR A 1 52  ? 123.391 133.192 112.669 1.00 56.85  ? 67  TYR L C   1 
ATOM 364  O O   . TYR A 1 52  ? 123.731 132.351 111.836 1.00 56.85  ? 67  TYR L O   1 
ATOM 365  C CB  . TYR A 1 52  ? 121.782 131.726 113.903 1.00 56.85  ? 67  TYR L CB  1 
ATOM 366  C CG  . TYR A 1 52  ? 120.702 132.107 112.919 1.00 56.85  ? 67  TYR L CG  1 
ATOM 367  C CD1 . TYR A 1 52  ? 119.661 132.943 113.291 1.00 56.85  ? 67  TYR L CD1 1 
ATOM 368  C CD2 . TYR A 1 52  ? 120.702 131.601 111.628 1.00 56.85  ? 67  TYR L CD2 1 
ATOM 369  C CE1 . TYR A 1 52  ? 118.665 133.282 112.400 1.00 56.85  ? 67  TYR L CE1 1 
ATOM 370  C CE2 . TYR A 1 52  ? 119.712 131.936 110.730 1.00 56.85  ? 67  TYR L CE2 1 
ATOM 371  C CZ  . TYR A 1 52  ? 118.696 132.776 111.121 1.00 56.85  ? 67  TYR L CZ  1 
ATOM 372  O OH  . TYR A 1 52  ? 117.705 133.112 110.229 1.00 56.85  ? 67  TYR L OH  1 
ATOM 373  N N   . ALA A 1 53  ? 123.412 134.493 112.398 1.00 54.71  ? 68  ALA L N   1 
ATOM 374  C CA  . ALA A 1 53  ? 123.952 134.938 111.119 1.00 54.71  ? 68  ALA L CA  1 
ATOM 375  C C   . ALA A 1 53  ? 125.007 136.016 111.314 1.00 54.71  ? 68  ALA L C   1 
ATOM 376  O O   . ALA A 1 53  ? 126.053 135.991 110.659 1.00 54.71  ? 68  ALA L O   1 
ATOM 377  C CB  . ALA A 1 53  ? 122.836 135.452 110.211 1.00 54.71  ? 68  ALA L CB  1 
ATOM 378  N N   . ALA A 1 54  ? 124.739 136.927 112.251 1.00 59.55  ? 69  ALA L N   1 
ATOM 379  C CA  . ALA A 1 54  ? 125.531 138.112 112.567 1.00 59.55  ? 69  ALA L CA  1 
ATOM 380  C C   . ALA A 1 54  ? 124.627 139.083 113.310 1.00 59.55  ? 69  ALA L C   1 
ATOM 381  O O   . ALA A 1 54  ? 124.988 139.603 114.369 1.00 59.55  ? 69  ALA L O   1 
ATOM 382  C CB  . ALA A 1 54  ? 126.103 138.792 111.321 1.00 59.55  ? 69  ALA L CB  1 
ATOM 383  N N   . ALA A 1 55  ? 123.440 139.321 112.752 1.00 61.12  ? 70  ALA L N   1 
ATOM 384  C CA  . ALA A 1 55  ? 122.455 140.208 113.342 1.00 61.12  ? 70  ALA L CA  1 
ATOM 385  C C   . ALA A 1 55  ? 121.093 139.564 113.542 1.00 61.12  ? 70  ALA L C   1 
ATOM 386  O O   . ALA A 1 55  ? 120.141 140.274 113.885 1.00 61.12  ? 70  ALA L O   1 
ATOM 387  C CB  . ALA A 1 55  ? 122.286 141.468 112.479 1.00 61.12  ? 70  ALA L CB  1 
ATOM 388  N N   . LYS A 1 56  ? 120.966 138.255 113.343 1.00 61.48  ? 71  LYS L N   1 
ATOM 389  C CA  . LYS A 1 56  ? 119.672 137.592 113.386 1.00 61.48  ? 71  LYS L CA  1 
ATOM 390  C C   . LYS A 1 56  ? 119.481 136.833 114.692 1.00 61.48  ? 71  LYS L C   1 
ATOM 391  O O   . LYS A 1 56  ? 120.348 136.061 115.108 1.00 61.48  ? 71  LYS L O   1 
ATOM 392  C CB  . LYS A 1 56  ? 119.534 136.629 112.208 1.00 61.48  ? 71  LYS L CB  1 
ATOM 393  C CG  . LYS A 1 56  ? 119.474 137.306 110.856 1.00 61.48  ? 71  LYS L CG  1 
ATOM 394  C CD  . LYS A 1 56  ? 119.284 136.287 109.749 1.00 61.48  ? 71  LYS L CD  1 
ATOM 395  C CE  . LYS A 1 56  ? 119.303 136.951 108.388 1.00 61.48  ? 71  LYS L CE  1 
ATOM 396  N NZ  . LYS A 1 56  ? 118.115 137.828 108.203 1.00 61.48  ? 71  LYS L NZ  1 
ATOM 397  N N   . LEU A 1 57  ? 118.336 137.055 115.333 1.00 65.16  ? 72  LEU L N   1 
ATOM 398  C CA  . LEU A 1 57  ? 117.965 136.287 116.512 1.00 65.16  ? 72  LEU L CA  1 
ATOM 399  C C   . LEU A 1 57  ? 117.632 134.859 116.101 1.00 65.16  ? 72  LEU L C   1 
ATOM 400  O O   . LEU A 1 57  ? 117.091 134.617 115.019 1.00 65.16  ? 72  LEU L O   1 
ATOM 401  C CB  . LEU A 1 57  ? 116.772 136.928 117.224 1.00 65.16  ? 72  LEU L CB  1 
ATOM 402  C CG  . LEU A 1 57  ? 117.037 138.094 118.187 1.00 65.16  ? 72  LEU L CG  1 
ATOM 403  C CD1 . LEU A 1 57  ? 117.876 137.651 119.372 1.00 65.16  ? 72  LEU L CD1 1 
ATOM 404  C CD2 . LEU A 1 57  ? 117.677 139.290 117.492 1.00 65.16  ? 72  LEU L CD2 1 
ATOM 405  N N   . ALA A 1 58  ? 117.954 133.903 116.974 1.00 69.06  ? 73  ALA L N   1 
ATOM 406  C CA  . ALA A 1 58  ? 118.053 132.520 116.508 1.00 69.06  ? 73  ALA L CA  1 
ATOM 407  C C   . ALA A 1 58  ? 116.692 131.837 116.394 1.00 69.06  ? 73  ALA L C   1 
ATOM 408  O O   . ALA A 1 58  ? 116.207 131.587 115.286 1.00 69.06  ? 73  ALA L O   1 
ATOM 409  C CB  . ALA A 1 58  ? 118.975 131.729 117.440 1.00 69.06  ? 73  ALA L CB  1 
ATOM 410  N N   . ASP A 1 59  ? 116.056 131.526 117.523 1.00 79.22  ? 74  ASP L N   1 
ATOM 411  C CA  . ASP A 1 59  ? 114.734 130.914 117.439 1.00 79.22  ? 74  ASP L CA  1 
ATOM 412  C C   . ASP A 1 59  ? 113.680 131.672 118.234 1.00 79.22  ? 74  ASP L C   1 
ATOM 413  O O   . ASP A 1 59  ? 112.681 132.136 117.676 1.00 79.22  ? 74  ASP L O   1 
ATOM 414  C CB  . ASP A 1 59  ? 114.800 129.461 117.916 1.00 79.22  ? 74  ASP L CB  1 
ATOM 415  C CG  . ASP A 1 59  ? 113.604 128.639 117.461 1.00 79.22  ? 74  ASP L CG  1 
ATOM 416  O OD1 . ASP A 1 59  ? 112.467 129.154 117.487 1.00 79.22  ? 74  ASP L OD1 1 
ATOM 417  O OD2 . ASP A 1 59  ? 113.806 127.469 117.072 1.00 79.22  ? 74  ASP L OD2 1 
ATOM 418  N N   . GLY A 1 60  ? 113.902 131.801 119.538 1.00 81.34  ? 75  GLY L N   1 
ATOM 419  C CA  . GLY A 1 60  ? 112.912 132.373 120.428 1.00 81.34  ? 75  GLY L CA  1 
ATOM 420  C C   . GLY A 1 60  ? 113.530 133.175 121.550 1.00 81.34  ? 75  GLY L C   1 
ATOM 421  O O   . GLY A 1 60  ? 112.825 133.662 122.439 1.00 81.34  ? 75  GLY L O   1 
ATOM 422  N N   . VAL A 1 61  ? 114.853 133.295 121.525 1.00 78.30  ? 76  VAL L N   1 
ATOM 423  C CA  . VAL A 1 61  ? 115.564 134.034 122.573 1.00 78.30  ? 76  VAL L CA  1 
ATOM 424  C C   . VAL A 1 61  ? 115.056 135.473 122.603 1.00 78.30  ? 76  VAL L C   1 
ATOM 425  O O   . VAL A 1 61  ? 114.848 136.078 121.532 1.00 78.30  ? 76  VAL L O   1 
ATOM 426  C CB  . VAL A 1 61  ? 117.085 133.968 122.329 1.00 78.30  ? 76  VAL L CB  1 
ATOM 427  C CG1 . VAL A 1 61  ? 117.440 134.532 120.968 1.00 78.30  ? 76  VAL L CG1 1 
ATOM 428  C CG2 . VAL A 1 61  ? 117.849 134.691 123.420 1.00 78.30  ? 76  VAL L CG2 1 
ATOM 429  N N   . PRO A 1 62  ? 114.794 136.050 123.778 1.00 82.06  ? 77  PRO L N   1 
ATOM 430  C CA  . PRO A 1 62  ? 114.175 137.380 123.826 1.00 82.06  ? 77  PRO L CA  1 
ATOM 431  C C   . PRO A 1 62  ? 115.032 138.437 123.148 1.00 82.06  ? 77  PRO L C   1 
ATOM 432  O O   . PRO A 1 62  ? 116.263 138.383 123.168 1.00 82.06  ? 77  PRO L O   1 
ATOM 433  C CB  . PRO A 1 62  ? 114.034 137.653 125.329 1.00 82.06  ? 77  PRO L CB  1 
ATOM 434  C CG  . PRO A 1 62  ? 114.980 136.701 125.988 1.00 82.06  ? 77  PRO L CG  1 
ATOM 435  C CD  . PRO A 1 62  ? 114.972 135.484 125.125 1.00 82.06  ? 77  PRO L CD  1 
ATOM 436  N N   . SER A 1 63  ? 114.355 139.415 122.546 1.00 83.23  ? 78  SER L N   1 
ATOM 437  C CA  . SER A 1 63  ? 115.007 140.412 121.700 1.00 83.23  ? 78  SER L CA  1 
ATOM 438  C C   . SER A 1 63  ? 115.691 141.492 122.543 1.00 83.23  ? 78  SER L C   1 
ATOM 439  O O   . SER A 1 63  ? 115.451 142.690 122.400 1.00 83.23  ? 78  SER L O   1 
ATOM 440  C CB  . SER A 1 63  ? 113.996 141.019 120.737 1.00 83.23  ? 78  SER L CB  1 
ATOM 441  O OG  . SER A 1 63  ? 114.504 142.200 120.141 1.00 83.23  ? 78  SER L OG  1 
ATOM 442  N N   . ARG A 1 64  ? 116.567 141.039 123.437 1.00 83.05  ? 79  ARG L N   1 
ATOM 443  C CA  . ARG A 1 64  ? 117.460 141.928 124.161 1.00 83.05  ? 79  ARG L CA  1 
ATOM 444  C C   . ARG A 1 64  ? 118.921 141.668 123.832 1.00 83.05  ? 79  ARG L C   1 
ATOM 445  O O   . ARG A 1 64  ? 119.796 142.348 124.380 1.00 83.05  ? 79  ARG L O   1 
ATOM 446  C CB  . ARG A 1 64  ? 117.232 141.814 125.675 1.00 83.05  ? 79  ARG L CB  1 
ATOM 447  C CG  . ARG A 1 64  ? 117.604 140.476 126.282 1.00 83.05  ? 79  ARG L CG  1 
ATOM 448  C CD  . ARG A 1 64  ? 116.979 140.330 127.658 1.00 83.05  ? 79  ARG L CD  1 
ATOM 449  N NE  . ARG A 1 64  ? 116.778 138.937 128.034 1.00 83.05  ? 79  ARG L NE  1 
ATOM 450  C CZ  . ARG A 1 64  ? 117.562 138.268 128.868 1.00 83.05  ? 79  ARG L CZ  1 
ATOM 451  N NH1 . ARG A 1 64  ? 118.618 138.835 129.426 1.00 83.05  ? 79  ARG L NH1 1 
ATOM 452  N NH2 . ARG A 1 64  ? 117.277 137.000 129.151 1.00 83.05  ? 79  ARG L NH2 1 
ATOM 453  N N   . PHE A 1 65  ? 119.207 140.708 122.957 1.00 76.84  ? 80  PHE L N   1 
ATOM 454  C CA  . PHE A 1 65  ? 120.534 140.495 122.403 1.00 76.84  ? 80  PHE L CA  1 
ATOM 455  C C   . PHE A 1 65  ? 120.551 141.000 120.968 1.00 76.84  ? 80  PHE L C   1 
ATOM 456  O O   . PHE A 1 65  ? 119.596 140.780 120.216 1.00 76.84  ? 80  PHE L O   1 
ATOM 457  C CB  . PHE A 1 65  ? 120.925 139.015 122.427 1.00 76.84  ? 80  PHE L CB  1 
ATOM 458  C CG  . PHE A 1 65  ? 120.783 138.366 123.771 1.00 76.84  ? 80  PHE L CG  1 
ATOM 459  C CD1 . PHE A 1 65  ? 119.605 137.738 124.130 1.00 76.84  ? 80  PHE L CD1 1 
ATOM 460  C CD2 . PHE A 1 65  ? 121.833 138.370 124.671 1.00 76.84  ? 80  PHE L CD2 1 
ATOM 461  C CE1 . PHE A 1 65  ? 119.475 137.135 125.364 1.00 76.84  ? 80  PHE L CE1 1 
ATOM 462  C CE2 . PHE A 1 65  ? 121.709 137.767 125.906 1.00 76.84  ? 80  PHE L CE2 1 
ATOM 463  C CZ  . PHE A 1 65  ? 120.528 137.148 126.252 1.00 76.84  ? 80  PHE L CZ  1 
ATOM 464  N N   . SER A 1 66  ? 121.629 141.679 120.587 1.00 74.56  ? 81  SER L N   1 
ATOM 465  C CA  . SER A 1 66  ? 121.727 142.194 119.228 1.00 74.56  ? 81  SER L CA  1 
ATOM 466  C C   . SER A 1 66  ? 123.174 142.140 118.768 1.00 74.56  ? 81  SER L C   1 
ATOM 467  O O   . SER A 1 66  ? 124.081 142.529 119.508 1.00 74.56  ? 81  SER L O   1 
ATOM 468  C CB  . SER A 1 66  ? 121.189 143.625 119.139 1.00 74.56  ? 81  SER L CB  1 
ATOM 469  O OG  . SER A 1 66  ? 121.820 144.472 120.081 1.00 74.56  ? 81  SER L OG  1 
ATOM 470  N N   . GLY A 1 67  ? 123.378 141.666 117.544 1.00 70.32  ? 82  GLY L N   1 
ATOM 471  C CA  . GLY A 1 67  ? 124.701 141.580 116.962 1.00 70.32  ? 82  GLY L CA  1 
ATOM 472  C C   . GLY A 1 67  ? 124.781 142.392 115.685 1.00 70.32  ? 82  GLY L C   1 
ATOM 473  O O   . GLY A 1 67  ? 123.768 142.678 115.048 1.00 70.32  ? 82  GLY L O   1 
ATOM 474  N N   . SER A 1 68  ? 126.002 142.771 115.324 1.00 69.23  ? 83  SER L N   1 
ATOM 475  C CA  . SER A 1 68  ? 126.274 143.489 114.088 1.00 69.23  ? 83  SER L CA  1 
ATOM 476  C C   . SER A 1 68  ? 127.768 143.424 113.834 1.00 69.23  ? 83  SER L C   1 
ATOM 477  O O   . SER A 1 68  ? 128.557 143.278 114.771 1.00 69.23  ? 83  SER L O   1 
ATOM 478  C CB  . SER A 1 68  ? 125.805 144.945 114.159 1.00 69.23  ? 83  SER L CB  1 
ATOM 479  O OG  . SER A 1 68  ? 126.036 145.610 112.930 1.00 69.23  ? 83  SER L OG  1 
ATOM 480  N N   . GLY A 1 69  ? 128.151 143.529 112.566 1.00 70.11  ? 84  GLY L N   1 
ATOM 481  C CA  . GLY A 1 69  ? 129.555 143.392 112.237 1.00 70.11  ? 84  GLY L CA  1 
ATOM 482  C C   . GLY A 1 69  ? 129.922 144.012 110.911 1.00 70.11  ? 84  GLY L C   1 
ATOM 483  O O   . GLY A 1 69  ? 129.091 144.159 110.010 1.00 70.11  ? 84  GLY L O   1 
ATOM 484  N N   . SER A 1 70  ? 131.196 144.366 110.807 1.00 70.40  ? 85  SER L N   1 
ATOM 485  C CA  . SER A 1 70  ? 131.788 144.891 109.587 1.00 70.40  ? 85  SER L CA  1 
ATOM 486  C C   . SER A 1 70  ? 132.341 143.724 108.771 1.00 70.40  ? 85  SER L C   1 
ATOM 487  O O   . SER A 1 70  ? 132.005 142.563 109.020 1.00 70.40  ? 85  SER L O   1 
ATOM 488  C CB  . SER A 1 70  ? 132.856 145.933 109.933 1.00 70.40  ? 85  SER L CB  1 
ATOM 489  O OG  . SER A 1 70  ? 133.501 146.406 108.764 1.00 70.40  ? 85  SER L OG  1 
ATOM 490  N N   . GLY A 1 71  ? 133.175 144.018 107.773 1.00 66.04  ? 86  GLY L N   1 
ATOM 491  C CA  . GLY A 1 71  ? 133.758 142.952 106.975 1.00 66.04  ? 86  GLY L CA  1 
ATOM 492  C C   . GLY A 1 71  ? 134.593 141.987 107.794 1.00 66.04  ? 86  GLY L C   1 
ATOM 493  O O   . GLY A 1 71  ? 134.537 140.774 107.585 1.00 66.04  ? 86  GLY L O   1 
ATOM 494  N N   . THR A 1 72  ? 135.375 142.506 108.743 1.00 68.23  ? 87  THR L N   1 
ATOM 495  C CA  . THR A 1 72  ? 136.279 141.671 109.523 1.00 68.23  ? 87  THR L CA  1 
ATOM 496  C C   . THR A 1 72  ? 136.216 141.947 111.021 1.00 68.23  ? 87  THR L C   1 
ATOM 497  O O   . THR A 1 72  ? 137.120 141.525 111.751 1.00 68.23  ? 87  THR L O   1 
ATOM 498  C CB  . THR A 1 72  ? 137.720 141.843 109.035 1.00 68.23  ? 87  THR L CB  1 
ATOM 499  O OG1 . THR A 1 72  ? 138.573 140.931 109.735 1.00 68.23  ? 87  THR L OG1 1 
ATOM 500  C CG2 . THR A 1 72  ? 138.197 143.265 109.279 1.00 68.23  ? 87  THR L CG2 1 
ATOM 501  N N   . GLN A 1 73  ? 135.181 142.633 111.502 1.00 69.89  ? 88  GLN L N   1 
ATOM 502  C CA  . GLN A 1 73  ? 135.056 142.934 112.925 1.00 69.89  ? 88  GLN L CA  1 
ATOM 503  C C   . GLN A 1 73  ? 133.581 142.920 113.292 1.00 69.89  ? 88  GLN L C   1 
ATOM 504  O O   . GLN A 1 73  ? 132.795 143.681 112.721 1.00 69.89  ? 88  GLN L O   1 
ATOM 505  C CB  . GLN A 1 73  ? 135.687 144.288 113.255 1.00 69.89  ? 88  GLN L CB  1 
ATOM 506  C CG  . GLN A 1 73  ? 136.099 144.443 114.707 1.00 69.89  ? 88  GLN L CG  1 
ATOM 507  C CD  . GLN A 1 73  ? 137.379 145.240 114.867 1.00 69.89  ? 88  GLN L CD  1 
ATOM 508  O OE1 . GLN A 1 73  ? 137.877 145.836 113.912 1.00 69.89  ? 88  GLN L OE1 1 
ATOM 509  N NE2 . GLN A 1 73  ? 137.922 145.251 116.079 1.00 69.89  ? 88  GLN L NE2 1 
ATOM 510  N N   . TYR A 1 74  ? 133.210 142.064 114.241 1.00 65.78  ? 89  TYR L N   1 
ATOM 511  C CA  . TYR A 1 74  ? 131.817 141.845 114.596 1.00 65.78  ? 89  TYR L CA  1 
ATOM 512  C C   . TYR A 1 74  ? 131.629 142.032 116.095 1.00 65.78  ? 89  TYR L C   1 
ATOM 513  O O   . TYR A 1 74  ? 132.546 141.794 116.886 1.00 65.78  ? 89  TYR L O   1 
ATOM 514  C CB  . TYR A 1 74  ? 131.341 140.443 114.175 1.00 65.78  ? 89  TYR L CB  1 
ATOM 515  C CG  . TYR A 1 74  ? 131.515 140.143 112.699 1.00 65.78  ? 89  TYR L CG  1 
ATOM 516  C CD1 . TYR A 1 74  ? 132.775 139.954 112.149 1.00 65.78  ? 89  TYR L CD1 1 
ATOM 517  C CD2 . TYR A 1 74  ? 130.418 140.065 111.854 1.00 65.78  ? 89  TYR L CD2 1 
ATOM 518  C CE1 . TYR A 1 74  ? 132.938 139.690 110.809 1.00 65.78  ? 89  TYR L CE1 1 
ATOM 519  C CE2 . TYR A 1 74  ? 130.573 139.802 110.510 1.00 65.78  ? 89  TYR L CE2 1 
ATOM 520  C CZ  . TYR A 1 74  ? 131.835 139.615 109.995 1.00 65.78  ? 89  TYR L CZ  1 
ATOM 521  O OH  . TYR A 1 74  ? 131.999 139.352 108.657 1.00 65.78  ? 89  TYR L OH  1 
ATOM 522  N N   . SER A 1 75  ? 130.426 142.457 116.479 1.00 68.20  ? 90  SER L N   1 
ATOM 523  C CA  . SER A 1 75  ? 130.132 142.832 117.853 1.00 68.20  ? 90  SER L CA  1 
ATOM 524  C C   . SER A 1 75  ? 128.807 142.229 118.300 1.00 68.20  ? 90  SER L C   1 
ATOM 525  O O   . SER A 1 75  ? 127.932 141.916 117.491 1.00 68.20  ? 90  SER L O   1 
ATOM 526  C CB  . SER A 1 75  ? 130.088 144.355 118.019 1.00 68.20  ? 90  SER L CB  1 
ATOM 527  O OG  . SER A 1 75  ? 128.915 144.893 117.436 1.00 68.20  ? 90  SER L OG  1 
ATOM 528  N N   . PHE A 1 76  ? 128.680 142.077 119.616 1.00 69.06  ? 91  PHE L N   1 
ATOM 529  C CA  . PHE A 1 76  ? 127.508 141.510 120.265 1.00 69.06  ? 91  PHE L CA  1 
ATOM 530  C C   . PHE A 1 76  ? 127.216 142.319 121.520 1.00 69.06  ? 91  PHE L C   1 
ATOM 531  O O   . PHE A 1 76  ? 128.132 142.626 122.291 1.00 69.06  ? 91  PHE L O   1 
ATOM 532  C CB  . PHE A 1 76  ? 127.742 140.037 120.616 1.00 69.06  ? 91  PHE L CB  1 
ATOM 533  C CG  . PHE A 1 76  ? 126.563 139.360 121.244 1.00 69.06  ? 91  PHE L CG  1 
ATOM 534  C CD1 . PHE A 1 76  ? 125.387 139.195 120.540 1.00 69.06  ? 91  PHE L CD1 1 
ATOM 535  C CD2 . PHE A 1 76  ? 126.641 138.864 122.532 1.00 69.06  ? 91  PHE L CD2 1 
ATOM 536  C CE1 . PHE A 1 76  ? 124.305 138.561 121.113 1.00 69.06  ? 91  PHE L CE1 1 
ATOM 537  C CE2 . PHE A 1 76  ? 125.563 138.230 123.111 1.00 69.06  ? 91  PHE L CE2 1 
ATOM 538  C CZ  . PHE A 1 76  ? 124.395 138.078 122.400 1.00 69.06  ? 91  PHE L CZ  1 
ATOM 539  N N   . LYS A 1 77  ? 125.945 142.658 121.732 1.00 75.96  ? 92  LYS L N   1 
ATOM 540  C CA  . LYS A 1 77  ? 125.589 143.523 122.846 1.00 75.96  ? 92  LYS L CA  1 
ATOM 541  C C   . LYS A 1 77  ? 124.241 143.112 123.419 1.00 75.96  ? 92  LYS L C   1 
ATOM 542  O O   . LYS A 1 77  ? 123.422 142.471 122.753 1.00 75.96  ? 92  LYS L O   1 
ATOM 543  C CB  . LYS A 1 77  ? 125.565 144.997 122.424 1.00 75.96  ? 92  LYS L CB  1 
ATOM 544  C CG  . LYS A 1 77  ? 124.679 145.287 121.229 1.00 75.96  ? 92  LYS L CG  1 
ATOM 545  C CD  . LYS A 1 77  ? 124.359 146.769 121.124 1.00 75.96  ? 92  LYS L CD  1 
ATOM 546  C CE  . LYS A 1 77  ? 123.660 147.272 122.374 1.00 75.96  ? 92  LYS L CE  1 
ATOM 547  N NZ  . LYS A 1 77  ? 122.224 146.880 122.403 1.00 75.96  ? 92  LYS L NZ  1 
ATOM 548  N N   . ILE A 1 78  ? 124.028 143.492 124.678 1.00 81.86  ? 93  ILE L N   1 
ATOM 549  C CA  . ILE A 1 78  ? 122.808 143.198 125.419 1.00 81.86  ? 93  ILE L CA  1 
ATOM 550  C C   . ILE A 1 78  ? 122.283 144.500 126.007 1.00 81.86  ? 93  ILE L C   1 
ATOM 551  O O   . ILE A 1 78  ? 123.064 145.336 126.476 1.00 81.86  ? 93  ILE L O   1 
ATOM 552  C CB  . ILE A 1 78  ? 123.054 142.161 126.535 1.00 81.86  ? 93  ILE L CB  1 
ATOM 553  C CG1 . ILE A 1 78  ? 123.851 140.972 125.999 1.00 81.86  ? 93  ILE L CG1 1 
ATOM 554  C CG2 . ILE A 1 78  ? 121.738 141.686 127.125 1.00 81.86  ? 93  ILE L CG2 1 
ATOM 555  C CD1 . ILE A 1 78  ? 124.425 140.085 127.078 1.00 81.86  ? 93  ILE L CD1 1 
ATOM 556  N N   . ASN A 1 79  ? 120.962 144.675 125.984 1.00 87.37  ? 94  ASN L N   1 
ATOM 557  C CA  . ASN A 1 79  ? 120.349 145.898 126.494 1.00 87.37  ? 94  ASN L CA  1 
ATOM 558  C C   . ASN A 1 79  ? 120.222 145.875 128.016 1.00 87.37  ? 94  ASN L C   1 
ATOM 559  O O   . ASN A 1 79  ? 120.800 146.719 128.707 1.00 87.37  ? 94  ASN L O   1 
ATOM 560  C CB  . ASN A 1 79  ? 118.978 146.108 125.842 1.00 87.37  ? 94  ASN L CB  1 
ATOM 561  C CG  . ASN A 1 79  ? 119.082 146.629 124.424 1.00 87.37  ? 94  ASN L CG  1 
ATOM 562  O OD1 . ASN A 1 79  ? 120.177 146.880 123.920 1.00 87.37  ? 94  ASN L OD1 1 
ATOM 563  N ND2 . ASN A 1 79  ? 117.938 146.797 123.770 1.00 87.37  ? 94  ASN L ND2 1 
ATOM 564  N N   . SER A 1 80  ? 119.471 144.917 128.551 1.00 89.39  ? 95  SER L N   1 
ATOM 565  C CA  . SER A 1 80  ? 119.335 144.731 129.990 1.00 89.39  ? 95  SER L CA  1 
ATOM 566  C C   . SER A 1 80  ? 120.087 143.467 130.377 1.00 89.39  ? 95  SER L C   1 
ATOM 567  O O   . SER A 1 80  ? 119.770 142.379 129.884 1.00 89.39  ? 95  SER L O   1 
ATOM 568  C CB  . SER A 1 80  ? 117.865 144.636 130.399 1.00 89.39  ? 95  SER L CB  1 
ATOM 569  O OG  . SER A 1 80  ? 117.208 143.592 129.704 1.00 89.39  ? 95  SER L OG  1 
ATOM 570  N N   . LEU A 1 81  ? 121.083 143.611 131.255 1.00 89.44  ? 96  LEU L N   1 
ATOM 571  C CA  . LEU A 1 81  ? 121.955 142.482 131.562 1.00 89.44  ? 96  LEU L CA  1 
ATOM 572  C C   . LEU A 1 81  ? 121.176 141.346 132.216 1.00 89.44  ? 96  LEU L C   1 
ATOM 573  O O   . LEU A 1 81  ? 121.332 140.181 131.832 1.00 89.44  ? 96  LEU L O   1 
ATOM 574  C CB  . LEU A 1 81  ? 123.117 142.946 132.444 1.00 89.44  ? 96  LEU L CB  1 
ATOM 575  C CG  . LEU A 1 81  ? 124.285 141.996 132.737 1.00 89.44  ? 96  LEU L CG  1 
ATOM 576  C CD1 . LEU A 1 81  ? 125.546 142.800 132.994 1.00 89.44  ? 96  LEU L CD1 1 
ATOM 577  C CD2 . LEU A 1 81  ? 124.011 141.094 133.925 1.00 89.44  ? 96  LEU L CD2 1 
ATOM 578  N N   . GLN A 1 82  ? 120.329 141.667 133.199 1.00 89.27  ? 97  GLN L N   1 
ATOM 579  C CA  . GLN A 1 82  ? 119.416 140.720 133.839 1.00 89.27  ? 97  GLN L CA  1 
ATOM 580  C C   . GLN A 1 82  ? 120.187 139.604 134.549 1.00 89.27  ? 97  GLN L C   1 
ATOM 581  O O   . GLN A 1 82  ? 121.396 139.456 134.357 1.00 89.27  ? 97  GLN L O   1 
ATOM 582  C CB  . GLN A 1 82  ? 118.431 140.183 132.786 1.00 89.27  ? 97  GLN L CB  1 
ATOM 583  C CG  . GLN A 1 82  ? 117.265 139.327 133.280 1.00 89.27  ? 97  GLN L CG  1 
ATOM 584  C CD  . GLN A 1 82  ? 117.615 137.861 133.422 1.00 89.27  ? 97  GLN L CD  1 
ATOM 585  O OE1 . GLN A 1 82  ? 118.470 137.345 132.706 1.00 89.27  ? 97  GLN L OE1 1 
ATOM 586  N NE2 . GLN A 1 82  ? 116.948 137.179 134.346 1.00 89.27  ? 97  GLN L NE2 1 
ATOM 587  N N   . SER A 1 83  ? 119.516 138.826 135.393 1.00 89.82  ? 98  SER L N   1 
ATOM 588  C CA  . SER A 1 83  ? 120.162 137.768 136.163 1.00 89.82  ? 98  SER L CA  1 
ATOM 589  C C   . SER A 1 83  ? 119.887 136.426 135.495 1.00 89.82  ? 98  SER L C   1 
ATOM 590  O O   . SER A 1 83  ? 118.839 135.819 135.737 1.00 89.82  ? 98  SER L O   1 
ATOM 591  C CB  . SER A 1 83  ? 119.672 137.770 137.609 1.00 89.82  ? 98  SER L CB  1 
ATOM 592  O OG  . SER A 1 83  ? 120.459 136.907 138.411 1.00 89.82  ? 98  SER L OG  1 
ATOM 593  N N   . GLU A 1 84  ? 120.861 135.960 134.703 1.00 87.47  ? 99  GLU L N   1 
ATOM 594  C CA  . GLU A 1 84  ? 120.894 134.725 133.912 1.00 87.47  ? 99  GLU L CA  1 
ATOM 595  C C   . GLU A 1 84  ? 121.981 134.826 132.850 1.00 87.47  ? 99  GLU L C   1 
ATOM 596  O O   . GLU A 1 84  ? 122.569 133.814 132.458 1.00 87.47  ? 99  GLU L O   1 
ATOM 597  C CB  . GLU A 1 84  ? 119.567 134.395 133.210 1.00 87.47  ? 99  GLU L CB  1 
ATOM 598  C CG  . GLU A 1 84  ? 118.579 133.546 134.003 1.00 87.47  ? 99  GLU L CG  1 
ATOM 599  C CD  . GLU A 1 84  ? 117.147 133.745 133.548 1.00 87.47  ? 99  GLU L CD  1 
ATOM 600  O OE1 . GLU A 1 84  ? 116.458 132.736 133.292 1.00 87.47  ? 99  GLU L OE1 1 
ATOM 601  O OE2 . GLU A 1 84  ? 116.710 134.911 133.444 1.00 87.47  ? 99  GLU L OE2 1 
ATOM 602  N N   . ASP A 1 85  ? 122.252 136.042 132.377 1.00 82.68  ? 100 ASP L N   1 
ATOM 603  C CA  . ASP A 1 85  ? 123.167 136.254 131.257 1.00 82.68  ? 100 ASP L CA  1 
ATOM 604  C C   . ASP A 1 85  ? 124.606 136.211 131.764 1.00 82.68  ? 100 ASP L C   1 
ATOM 605  O O   . ASP A 1 85  ? 125.272 137.231 131.956 1.00 82.68  ? 100 ASP L O   1 
ATOM 606  C CB  . ASP A 1 85  ? 122.854 137.568 130.554 1.00 82.68  ? 100 ASP L CB  1 
ATOM 607  C CG  . ASP A 1 85  ? 121.529 137.529 129.821 1.00 82.68  ? 100 ASP L CG  1 
ATOM 608  O OD1 . ASP A 1 85  ? 121.127 136.433 129.383 1.00 82.68  ? 100 ASP L OD1 1 
ATOM 609  O OD2 . ASP A 1 85  ? 120.895 138.593 129.670 1.00 82.68  ? 100 ASP L OD2 1 
ATOM 610  N N   . PHE A 1 86  ? 125.093 134.990 131.971 1.00 82.05  ? 101 PHE L N   1 
ATOM 611  C CA  . PHE A 1 86  ? 126.467 134.748 132.383 1.00 82.05  ? 101 PHE L CA  1 
ATOM 612  C C   . PHE A 1 86  ? 126.924 133.434 131.767 1.00 82.05  ? 101 PHE L C   1 
ATOM 613  O O   . PHE A 1 86  ? 126.107 132.601 131.369 1.00 82.05  ? 101 PHE L O   1 
ATOM 614  C CB  . PHE A 1 86  ? 126.600 134.699 133.910 1.00 82.05  ? 101 PHE L CB  1 
ATOM 615  C CG  . PHE A 1 86  ? 126.168 135.962 134.600 1.00 82.05  ? 101 PHE L CG  1 
ATOM 616  C CD1 . PHE A 1 86  ? 126.998 137.071 134.632 1.00 82.05  ? 101 PHE L CD1 1 
ATOM 617  C CD2 . PHE A 1 86  ? 124.929 136.042 135.215 1.00 82.05  ? 101 PHE L CD2 1 
ATOM 618  C CE1 . PHE A 1 86  ? 126.602 138.235 135.268 1.00 82.05  ? 101 PHE L CE1 1 
ATOM 619  C CE2 . PHE A 1 86  ? 124.527 137.204 135.851 1.00 82.05  ? 101 PHE L CE2 1 
ATOM 620  C CZ  . PHE A 1 86  ? 125.365 138.302 135.877 1.00 82.05  ? 101 PHE L CZ  1 
ATOM 621  N N   . GLY A 1 87  ? 128.240 133.243 131.699 1.00 77.47  ? 102 GLY L N   1 
ATOM 622  C CA  . GLY A 1 87  ? 128.729 131.958 131.240 1.00 77.47  ? 102 GLY L CA  1 
ATOM 623  C C   . GLY A 1 87  ? 129.595 131.894 129.997 1.00 77.47  ? 102 GLY L C   1 
ATOM 624  O O   . GLY A 1 87  ? 129.505 130.925 129.239 1.00 77.47  ? 102 GLY L O   1 
ATOM 625  N N   . SER A 1 88  ? 130.443 132.897 129.768 1.00 73.52  ? 103 SER L N   1 
ATOM 626  C CA  . SER A 1 88  ? 131.512 132.796 128.773 1.00 73.52  ? 103 SER L CA  1 
ATOM 627  C C   . SER A 1 88  ? 130.954 132.573 127.362 1.00 73.52  ? 103 SER L C   1 
ATOM 628  O O   . SER A 1 88  ? 131.053 131.494 126.780 1.00 73.52  ? 103 SER L O   1 
ATOM 629  C CB  . SER A 1 88  ? 132.503 131.692 129.161 1.00 73.52  ? 103 SER L CB  1 
ATOM 630  O OG  . SER A 1 88  ? 131.957 130.408 128.921 1.00 73.52  ? 103 SER L OG  1 
ATOM 631  N N   . TYR A 1 89  ? 130.318 133.626 126.849 1.00 69.19  ? 104 TYR L N   1 
ATOM 632  C CA  . TYR A 1 89  ? 129.827 133.634 125.474 1.00 69.19  ? 104 TYR L CA  1 
ATOM 633  C C   . TYR A 1 89  ? 130.941 133.280 124.494 1.00 69.19  ? 104 TYR L C   1 
ATOM 634  O O   . TYR A 1 89  ? 132.105 133.629 124.703 1.00 69.19  ? 104 TYR L O   1 
ATOM 635  C CB  . TYR A 1 89  ? 129.264 135.014 125.123 1.00 69.19  ? 104 TYR L CB  1 
ATOM 636  C CG  . TYR A 1 89  ? 128.019 135.418 125.882 1.00 69.19  ? 104 TYR L CG  1 
ATOM 637  C CD1 . TYR A 1 89  ? 128.023 135.526 127.264 1.00 69.19  ? 104 TYR L CD1 1 
ATOM 638  C CD2 . TYR A 1 89  ? 126.840 135.696 125.211 1.00 69.19  ? 104 TYR L CD2 1 
ATOM 639  C CE1 . TYR A 1 89  ? 126.892 135.896 127.954 1.00 69.19  ? 104 TYR L CE1 1 
ATOM 640  C CE2 . TYR A 1 89  ? 125.703 136.065 125.894 1.00 69.19  ? 104 TYR L CE2 1 
ATOM 641  C CZ  . TYR A 1 89  ? 125.735 136.166 127.265 1.00 69.19  ? 104 TYR L CZ  1 
ATOM 642  O OH  . TYR A 1 89  ? 124.602 136.533 127.948 1.00 69.19  ? 104 TYR L OH  1 
ATOM 643  N N   . TYR A 1 90  ? 130.577 132.591 123.412 1.00 61.50  ? 105 TYR L N   1 
ATOM 644  C CA  . TYR A 1 90  ? 131.527 132.151 122.398 1.00 61.50  ? 105 TYR L CA  1 
ATOM 645  C C   . TYR A 1 90  ? 131.094 132.614 121.013 1.00 61.50  ? 105 TYR L C   1 
ATOM 646  O O   . TYR A 1 90  ? 129.909 132.848 120.761 1.00 61.50  ? 105 TYR L O   1 
ATOM 647  C CB  . TYR A 1 90  ? 131.673 130.624 122.383 1.00 61.50  ? 105 TYR L CB  1 
ATOM 648  C CG  . TYR A 1 90  ? 132.237 130.025 123.648 1.00 61.50  ? 105 TYR L CG  1 
ATOM 649  C CD1 . TYR A 1 90  ? 133.593 130.092 123.925 1.00 61.50  ? 105 TYR L CD1 1 
ATOM 650  C CD2 . TYR A 1 90  ? 131.418 129.363 124.549 1.00 61.50  ? 105 TYR L CD2 1 
ATOM 651  C CE1 . TYR A 1 90  ? 134.114 129.539 125.075 1.00 61.50  ? 105 TYR L CE1 1 
ATOM 652  C CE2 . TYR A 1 90  ? 131.930 128.805 125.700 1.00 61.50  ? 105 TYR L CE2 1 
ATOM 653  C CZ  . TYR A 1 90  ? 133.278 128.897 125.958 1.00 61.50  ? 105 TYR L CZ  1 
ATOM 654  O OH  . TYR A 1 90  ? 133.792 128.341 127.105 1.00 61.50  ? 105 TYR L OH  1 
ATOM 655  N N   . CYS A 1 91  ? 132.070 132.740 120.114 1.00 58.00  ? 106 CYS L N   1 
ATOM 656  C CA  . CYS A 1 91  ? 131.834 133.064 118.713 1.00 58.00  ? 106 CYS L CA  1 
ATOM 657  C C   . CYS A 1 91  ? 132.537 132.042 117.832 1.00 58.00  ? 106 CYS L C   1 
ATOM 658  O O   . CYS A 1 91  ? 133.636 131.583 118.159 1.00 58.00  ? 106 CYS L O   1 
ATOM 659  C CB  . CYS A 1 91  ? 132.331 134.476 118.370 1.00 58.00  ? 106 CYS L CB  1 
ATOM 660  S SG  . CYS A 1 91  ? 134.097 134.752 118.652 1.00 58.00  ? 106 CYS L SG  1 
ATOM 661  N N   . GLN A 1 92  ? 131.902 131.683 116.716 1.00 51.26  ? 107 GLN L N   1 
ATOM 662  C CA  . GLN A 1 92  ? 132.449 130.708 115.781 1.00 51.26  ? 107 GLN L CA  1 
ATOM 663  C C   . GLN A 1 92  ? 132.227 131.174 114.351 1.00 51.26  ? 107 GLN L C   1 
ATOM 664  O O   . GLN A 1 92  ? 131.156 131.684 114.017 1.00 51.26  ? 107 GLN L O   1 
ATOM 665  C CB  . GLN A 1 92  ? 131.810 129.334 115.975 1.00 51.26  ? 107 GLN L CB  1 
ATOM 666  C CG  . GLN A 1 92  ? 132.428 128.248 115.119 1.00 51.26  ? 107 GLN L CG  1 
ATOM 667  C CD  . GLN A 1 92  ? 131.717 126.923 115.256 1.00 51.26  ? 107 GLN L CD  1 
ATOM 668  O OE1 . GLN A 1 92  ? 130.539 126.871 115.600 1.00 51.26  ? 107 GLN L OE1 1 
ATOM 669  N NE2 . GLN A 1 92  ? 132.430 125.839 114.988 1.00 51.26  ? 107 GLN L NE2 1 
ATOM 670  N N   . HIS A 1 93  ? 133.238 130.985 113.507 1.00 49.42  ? 108 HIS L N   1 
ATOM 671  C CA  . HIS A 1 93  ? 133.171 131.355 112.102 1.00 49.42  ? 108 HIS L CA  1 
ATOM 672  C C   . HIS A 1 93  ? 132.907 130.126 111.243 1.00 49.42  ? 108 HIS L C   1 
ATOM 673  O O   . HIS A 1 93  ? 133.356 129.021 111.556 1.00 49.42  ? 108 HIS L O   1 
ATOM 674  C CB  . HIS A 1 93  ? 134.467 132.034 111.655 1.00 49.42  ? 108 HIS L CB  1 
ATOM 675  C CG  . HIS A 1 93  ? 135.529 131.080 111.207 1.00 49.42  ? 108 HIS L CG  1 
ATOM 676  N ND1 . HIS A 1 93  ? 135.570 130.553 109.935 1.00 49.42  ? 108 HIS L ND1 1 
ATOM 677  C CD2 . HIS A 1 93  ? 136.593 130.560 111.863 1.00 49.42  ? 108 HIS L CD2 1 
ATOM 678  C CE1 . HIS A 1 93  ? 136.612 129.748 109.827 1.00 49.42  ? 108 HIS L CE1 1 
ATOM 679  N NE2 . HIS A 1 93  ? 137.249 129.735 110.983 1.00 49.42  ? 108 HIS L NE2 1 
ATOM 680  N N   . PHE A 1 94  ? 132.179 130.328 110.149 1.00 45.76  ? 109 PHE L N   1 
ATOM 681  C CA  . PHE A 1 94  ? 131.792 129.253 109.245 1.00 45.76  ? 109 PHE L CA  1 
ATOM 682  C C   . PHE A 1 94  ? 132.203 129.554 107.810 1.00 45.76  ? 109 PHE L C   1 
ATOM 683  O O   . PHE A 1 94  ? 131.504 129.202 106.860 1.00 45.76  ? 109 PHE L O   1 
ATOM 684  C CB  . PHE A 1 94  ? 130.290 128.996 109.320 1.00 45.76  ? 109 PHE L CB  1 
ATOM 685  C CG  . PHE A 1 94  ? 129.859 128.287 110.565 1.00 45.76  ? 109 PHE L CG  1 
ATOM 686  C CD1 . PHE A 1 94  ? 130.067 126.931 110.708 1.00 45.76  ? 109 PHE L CD1 1 
ATOM 687  C CD2 . PHE A 1 94  ? 129.238 128.973 111.588 1.00 45.76  ? 109 PHE L CD2 1 
ATOM 688  C CE1 . PHE A 1 94  ? 129.670 126.274 111.849 1.00 45.76  ? 109 PHE L CE1 1 
ATOM 689  C CE2 . PHE A 1 94  ? 128.841 128.320 112.732 1.00 45.76  ? 109 PHE L CE2 1 
ATOM 690  C CZ  . PHE A 1 94  ? 129.057 126.970 112.862 1.00 45.76  ? 109 PHE L CZ  1 
ATOM 691  N N   . TRP A 1 95  ? 133.349 130.208 107.631 1.00 43.04  ? 110 TRP L N   1 
ATOM 692  C CA  . TRP A 1 95  ? 133.824 130.536 106.291 1.00 43.04  ? 110 TRP L CA  1 
ATOM 693  C C   . TRP A 1 95  ? 134.629 129.388 105.686 1.00 43.04  ? 110 TRP L C   1 
ATOM 694  O O   . TRP A 1 95  ? 134.257 128.843 104.643 1.00 43.04  ? 110 TRP L O   1 
ATOM 695  C CB  . TRP A 1 95  ? 134.646 131.828 106.330 1.00 43.04  ? 110 TRP L CB  1 
ATOM 696  C CG  . TRP A 1 95  ? 134.945 132.411 104.980 1.00 43.04  ? 110 TRP L CG  1 
ATOM 697  C CD1 . TRP A 1 95  ? 136.154 132.851 104.535 1.00 43.04  ? 110 TRP L CD1 1 
ATOM 698  C CD2 . TRP A 1 95  ? 134.020 132.627 103.905 1.00 43.04  ? 110 TRP L CD2 1 
ATOM 699  N NE1 . TRP A 1 95  ? 136.046 133.320 103.251 1.00 43.04  ? 110 TRP L NE1 1 
ATOM 700  C CE2 . TRP A 1 95  ? 134.745 133.195 102.842 1.00 43.04  ? 110 TRP L CE2 1 
ATOM 701  C CE3 . TRP A 1 95  ? 132.653 132.394 103.737 1.00 43.04  ? 110 TRP L CE3 1 
ATOM 702  C CZ2 . TRP A 1 95  ? 134.151 133.529 101.631 1.00 43.04  ? 110 TRP L CZ2 1 
ATOM 703  C CZ3 . TRP A 1 95  ? 132.067 132.726 102.537 1.00 43.04  ? 110 TRP L CZ3 1 
ATOM 704  C CH2 . TRP A 1 95  ? 132.814 133.288 101.499 1.00 43.04  ? 110 TRP L CH2 1 
ATOM 705  N N   . GLY A 1 96  ? 135.724 129.005 106.330 1.00 46.07  ? 111 GLY L N   1 
ATOM 706  C CA  . GLY A 1 96  ? 136.511 127.866 105.908 1.00 46.07  ? 111 GLY L CA  1 
ATOM 707  C C   . GLY A 1 96  ? 135.973 126.576 106.485 1.00 46.07  ? 111 GLY L C   1 
ATOM 708  O O   . GLY A 1 96  ? 134.833 126.497 106.945 1.00 46.07  ? 111 GLY L O   1 
ATOM 709  N N   . THR A 1 97  ? 136.799 125.536 106.426 1.00 48.29  ? 112 THR L N   1 
ATOM 710  C CA  . THR A 1 97  ? 136.462 124.293 107.112 1.00 48.29  ? 112 THR L CA  1 
ATOM 711  C C   . THR A 1 97  ? 136.730 124.292 108.621 1.00 48.29  ? 112 THR L C   1 
ATOM 712  O O   . THR A 1 97  ? 135.939 123.688 109.356 1.00 48.29  ? 112 THR L O   1 
ATOM 713  C CB  . THR A 1 97  ? 137.175 123.100 106.466 1.00 48.29  ? 112 THR L CB  1 
ATOM 714  O OG1 . THR A 1 97  ? 136.671 121.886 107.035 1.00 48.29  ? 112 THR L OG1 1 
ATOM 715  C CG2 . THR A 1 97  ? 138.674 123.161 106.663 1.00 48.29  ? 112 THR L CG2 1 
ATOM 716  N N   . PRO A 1 98  ? 137.809 124.905 109.139 1.00 50.24  ? 113 PRO L N   1 
ATOM 717  C CA  . PRO A 1 98  ? 138.186 124.611 110.534 1.00 50.24  ? 113 PRO L CA  1 
ATOM 718  C C   . PRO A 1 98  ? 137.133 124.980 111.567 1.00 50.24  ? 113 PRO L C   1 
ATOM 719  O O   . PRO A 1 98  ? 137.007 124.264 112.567 1.00 50.24  ? 113 PRO L O   1 
ATOM 720  C CB  . PRO A 1 98  ? 139.475 125.423 110.729 1.00 50.24  ? 113 PRO L CB  1 
ATOM 721  C CG  . PRO A 1 98  ? 139.940 125.753 109.365 1.00 50.24  ? 113 PRO L CG  1 
ATOM 722  C CD  . PRO A 1 98  ? 138.691 125.950 108.590 1.00 50.24  ? 113 PRO L CD  1 
ATOM 723  N N   . TRP A 1 99  ? 136.377 126.059 111.367 1.00 47.11  ? 114 TRP L N   1 
ATOM 724  C CA  . TRP A 1 99  ? 135.318 126.475 112.292 1.00 47.11  ? 114 TRP L CA  1 
ATOM 725  C C   . TRP A 1 99  ? 135.852 126.541 113.725 1.00 47.11  ? 114 TRP L C   1 
ATOM 726  O O   . TRP A 1 99  ? 135.430 125.805 114.617 1.00 47.11  ? 114 TRP L O   1 
ATOM 727  C CB  . TRP A 1 99  ? 134.107 125.543 112.189 1.00 47.11  ? 114 TRP L CB  1 
ATOM 728  C CG  . TRP A 1 99  ? 133.575 125.395 110.793 1.00 47.11  ? 114 TRP L CG  1 
ATOM 729  C CD1 . TRP A 1 99  ? 133.939 126.120 109.703 1.00 47.11  ? 114 TRP L CD1 1 
ATOM 730  C CD2 . TRP A 1 99  ? 132.577 124.471 110.342 1.00 47.11  ? 114 TRP L CD2 1 
ATOM 731  N NE1 . TRP A 1 99  ? 133.243 125.703 108.599 1.00 47.11  ? 114 TRP L NE1 1 
ATOM 732  C CE2 . TRP A 1 99  ? 132.397 124.691 108.965 1.00 47.11  ? 114 TRP L CE2 1 
ATOM 733  C CE3 . TRP A 1 99  ? 131.821 123.478 110.968 1.00 47.11  ? 114 TRP L CE3 1 
ATOM 734  C CZ2 . TRP A 1 99  ? 131.496 123.957 108.205 1.00 47.11  ? 114 TRP L CZ2 1 
ATOM 735  C CZ3 . TRP A 1 99  ? 130.926 122.749 110.210 1.00 47.11  ? 114 TRP L CZ3 1 
ATOM 736  C CH2 . TRP A 1 99  ? 130.771 122.993 108.844 1.00 47.11  ? 114 TRP L CH2 1 
ATOM 737  N N   . THR A 1 100 ? 136.797 127.461 113.929 1.00 52.81  ? 115 THR L N   1 
ATOM 738  C CA  . THR A 1 100 ? 137.746 127.351 115.032 1.00 52.81  ? 115 THR L CA  1 
ATOM 739  C C   . THR A 1 100 ? 137.191 127.773 116.388 1.00 52.81  ? 115 THR L C   1 
ATOM 740  O O   . THR A 1 100 ? 137.876 127.565 117.395 1.00 52.81  ? 115 THR L O   1 
ATOM 741  C CB  . THR A 1 100 ? 138.988 128.185 114.724 1.00 52.81  ? 115 THR L CB  1 
ATOM 742  O OG1 . THR A 1 100 ? 138.588 129.470 114.236 1.00 52.81  ? 115 THR L OG1 1 
ATOM 743  C CG2 . THR A 1 100 ? 139.846 127.498 113.682 1.00 52.81  ? 115 THR L CG2 1 
ATOM 744  N N   . PHE A 1 101 ? 136.001 128.378 116.445 1.00 51.63  ? 116 PHE L N   1 
ATOM 745  C CA  . PHE A 1 101 ? 135.458 128.926 117.690 1.00 51.63  ? 116 PHE L CA  1 
ATOM 746  C C   . PHE A 1 101 ? 136.301 130.088 118.203 1.00 51.63  ? 116 PHE L C   1 
ATOM 747  O O   . PHE A 1 101 ? 137.354 130.401 117.640 1.00 51.63  ? 116 PHE L O   1 
ATOM 748  C CB  . PHE A 1 101 ? 135.345 127.860 118.787 1.00 51.63  ? 116 PHE L CB  1 
ATOM 749  C CG  . PHE A 1 101 ? 134.095 127.039 118.721 1.00 51.63  ? 116 PHE L CG  1 
ATOM 750  C CD1 . PHE A 1 101 ? 132.920 127.503 119.276 1.00 51.63  ? 116 PHE L CD1 1 
ATOM 751  C CD2 . PHE A 1 101 ? 134.101 125.791 118.132 1.00 51.63  ? 116 PHE L CD2 1 
ATOM 752  C CE1 . PHE A 1 101 ? 131.771 126.747 119.226 1.00 51.63  ? 116 PHE L CE1 1 
ATOM 753  C CE2 . PHE A 1 101 ? 132.953 125.030 118.082 1.00 51.63  ? 116 PHE L CE2 1 
ATOM 754  C CZ  . PHE A 1 101 ? 131.788 125.509 118.629 1.00 51.63  ? 116 PHE L CZ  1 
ATOM 755  N N   . GLY A 1 102 ? 135.843 130.737 119.273 1.00 58.02  ? 117 GLY L N   1 
ATOM 756  C CA  . GLY A 1 102 ? 136.540 131.854 119.865 1.00 58.02  ? 117 GLY L CA  1 
ATOM 757  C C   . GLY A 1 102 ? 137.067 131.533 121.256 1.00 58.02  ? 117 GLY L C   1 
ATOM 758  O O   . GLY A 1 102 ? 136.897 130.436 121.785 1.00 58.02  ? 117 GLY L O   1 
ATOM 759  N N   . GLY A 1 103 ? 137.728 132.532 121.845 1.00 65.95  ? 118 GLY L N   1 
ATOM 760  C CA  . GLY A 1 103 ? 138.307 132.347 123.165 1.00 65.95  ? 118 GLY L CA  1 
ATOM 761  C C   . GLY A 1 103 ? 137.268 132.166 124.256 1.00 65.95  ? 118 GLY L C   1 
ATOM 762  O O   . GLY A 1 103 ? 137.409 131.297 125.120 1.00 65.95  ? 118 GLY L O   1 
ATOM 763  N N   . GLY A 1 104 ? 136.216 132.979 124.235 1.00 71.02  ? 119 GLY L N   1 
ATOM 764  C CA  . GLY A 1 104 ? 135.195 132.921 125.263 1.00 71.02  ? 119 GLY L CA  1 
ATOM 765  C C   . GLY A 1 104 ? 135.359 133.991 126.322 1.00 71.02  ? 119 GLY L C   1 
ATOM 766  O O   . GLY A 1 104 ? 136.435 134.129 126.910 1.00 71.02  ? 119 GLY L O   1 
ATOM 767  N N   . THR A 1 105 ? 134.301 134.759 126.573 1.00 75.55  ? 120 THR L N   1 
ATOM 768  C CA  . THR A 1 105 ? 134.344 135.868 127.513 1.00 75.55  ? 120 THR L CA  1 
ATOM 769  C C   . THR A 1 105 ? 133.266 135.712 128.575 1.00 75.55  ? 120 THR L C   1 
ATOM 770  O O   . THR A 1 105 ? 132.069 135.779 128.287 1.00 75.55  ? 120 THR L O   1 
ATOM 771  C CB  . THR A 1 105 ? 134.150 137.211 126.805 1.00 75.55  ? 120 THR L CB  1 
ATOM 772  O OG1 . THR A 1 105 ? 132.763 137.390 126.496 1.00 75.55  ? 120 THR L OG1 1 
ATOM 773  C CG2 . THR A 1 105 ? 134.942 137.245 125.527 1.00 75.55  ? 120 THR L CG2 1 
ATOM 774  N N   . LYS A 1 106 ? 133.707 135.542 129.818 1.00 77.81  ? 121 LYS L N   1 
ATOM 775  C CA  . LYS A 1 106 ? 132.814 135.382 130.954 1.00 77.81  ? 121 LYS L CA  1 
ATOM 776  C C   . LYS A 1 106 ? 132.224 136.729 131.345 1.00 77.81  ? 121 LYS L C   1 
ATOM 777  O O   . LYS A 1 106 ? 132.661 137.783 130.877 1.00 77.81  ? 121 LYS L O   1 
ATOM 778  C CB  . LYS A 1 106 ? 133.542 134.767 132.155 1.00 77.81  ? 121 LYS L CB  1 
ATOM 779  C CG  . LYS A 1 106 ? 134.413 133.573 131.813 1.00 77.81  ? 121 LYS L CG  1 
ATOM 780  C CD  . LYS A 1 106 ? 134.647 132.707 133.038 1.00 77.81  ? 121 LYS L CD  1 
ATOM 781  C CE  . LYS A 1 106 ? 133.336 132.162 133.582 1.00 77.81  ? 121 LYS L CE  1 
ATOM 782  N NZ  . LYS A 1 106 ? 133.438 131.793 135.020 1.00 77.81  ? 121 LYS L NZ  1 
ATOM 783  N N   . LEU A 1 107 ? 131.213 136.681 132.206 1.00 79.27  ? 122 LEU L N   1 
ATOM 784  C CA  . LEU A 1 107 ? 130.588 137.892 132.722 1.00 79.27  ? 122 LEU L CA  1 
ATOM 785  C C   . LEU A 1 107 ? 130.456 137.832 134.239 1.00 79.27  ? 122 LEU L C   1 
ATOM 786  O O   . LEU A 1 107 ? 130.169 136.778 134.805 1.00 79.27  ? 122 LEU L O   1 
ATOM 787  C CB  . LEU A 1 107 ? 129.214 138.107 132.085 1.00 79.27  ? 122 LEU L CB  1 
ATOM 788  C CG  . LEU A 1 107 ? 129.187 138.452 130.597 1.00 79.27  ? 122 LEU L CG  1 
ATOM 789  C CD1 . LEU A 1 107 ? 127.756 138.653 130.131 1.00 79.27  ? 122 LEU L CD1 1 
ATOM 790  C CD2 . LEU A 1 107 ? 130.022 139.689 130.319 1.00 79.27  ? 122 LEU L CD2 1 
ATOM 791  N N   . VAL B 2 5   ? 112.077 116.982 118.819 1.00 62.94  ? 21  VAL H N   1 
ATOM 792  C CA  . VAL B 2 5   ? 113.494 116.994 118.482 1.00 62.94  ? 21  VAL H CA  1 
ATOM 793  C C   . VAL B 2 5   ? 114.355 116.939 119.741 1.00 62.94  ? 21  VAL H C   1 
ATOM 794  O O   . VAL B 2 5   ? 114.207 117.756 120.650 1.00 62.94  ? 21  VAL H O   1 
ATOM 795  C CB  . VAL B 2 5   ? 113.842 118.222 117.615 1.00 62.94  ? 21  VAL H CB  1 
ATOM 796  C CG1 . VAL B 2 5   ? 113.462 119.510 118.324 1.00 62.94  ? 21  VAL H CG1 1 
ATOM 797  C CG2 . VAL B 2 5   ? 115.316 118.217 117.268 1.00 62.94  ? 21  VAL H CG2 1 
ATOM 798  N N   . GLN B 2 6   ? 115.249 115.952 119.797 1.00 64.05  ? 22  GLN H N   1 
ATOM 799  C CA  . GLN B 2 6   ? 116.101 115.775 120.966 1.00 64.05  ? 22  GLN H CA  1 
ATOM 800  C C   . GLN B 2 6   ? 117.269 114.843 120.668 1.00 64.05  ? 22  GLN H C   1 
ATOM 801  O O   . GLN B 2 6   ? 117.090 113.779 120.066 1.00 64.05  ? 22  GLN H O   1 
ATOM 802  C CB  . GLN B 2 6   ? 115.282 115.239 122.142 1.00 64.05  ? 22  GLN H CB  1 
ATOM 803  C CG  . GLN B 2 6   ? 116.095 114.502 123.188 1.00 64.05  ? 22  GLN H CG  1 
ATOM 804  C CD  . GLN B 2 6   ? 115.262 114.089 124.382 1.00 64.05  ? 22  GLN H CD  1 
ATOM 805  O OE1 . GLN B 2 6   ? 114.137 114.556 124.560 1.00 64.05  ? 22  GLN H OE1 1 
ATOM 806  N NE2 . GLN B 2 6   ? 115.811 113.210 125.211 1.00 64.05  ? 22  GLN H NE2 1 
ATOM 807  N N   . LEU B 2 7   ? 118.468 115.240 121.085 1.00 63.05  ? 23  LEU H N   1 
ATOM 808  C CA  . LEU B 2 7   ? 119.664 114.419 120.963 1.00 63.05  ? 23  LEU H CA  1 
ATOM 809  C C   . LEU B 2 7   ? 120.112 113.990 122.353 1.00 63.05  ? 23  LEU H C   1 
ATOM 810  O O   . LEU B 2 7   ? 120.284 114.833 123.238 1.00 63.05  ? 23  LEU H O   1 
ATOM 811  C CB  . LEU B 2 7   ? 120.787 115.186 120.262 1.00 63.05  ? 23  LEU H CB  1 
ATOM 812  C CG  . LEU B 2 7   ? 120.715 115.355 118.744 1.00 63.05  ? 23  LEU H CG  1 
ATOM 813  C CD1 . LEU B 2 7   ? 119.731 116.444 118.357 1.00 63.05  ? 23  LEU H CD1 1 
ATOM 814  C CD2 . LEU B 2 7   ? 122.090 115.656 118.182 1.00 63.05  ? 23  LEU H CD2 1 
ATOM 815  N N   . GLN B 2 8   ? 120.301 112.687 122.543 1.00 65.96  ? 24  GLN H N   1 
ATOM 816  C CA  . GLN B 2 8   ? 120.698 112.148 123.837 1.00 65.96  ? 24  GLN H CA  1 
ATOM 817  C C   . GLN B 2 8   ? 121.936 111.279 123.686 1.00 65.96  ? 24  GLN H C   1 
ATOM 818  O O   . GLN B 2 8   ? 122.070 110.532 122.711 1.00 65.96  ? 24  GLN H O   1 
ATOM 819  C CB  . GLN B 2 8   ? 119.562 111.344 124.477 1.00 65.96  ? 24  GLN H CB  1 
ATOM 820  C CG  . GLN B 2 8   ? 118.983 110.263 123.590 1.00 65.96  ? 24  GLN H CG  1 
ATOM 821  C CD  . GLN B 2 8   ? 117.566 109.899 123.980 1.00 65.96  ? 24  GLN H CD  1 
ATOM 822  O OE1 . GLN B 2 8   ? 117.134 110.160 125.102 1.00 65.96  ? 24  GLN H OE1 1 
ATOM 823  N NE2 . GLN B 2 8   ? 116.832 109.298 123.051 1.00 65.96  ? 24  GLN H NE2 1 
ATOM 824  N N   . GLN B 2 9   ? 122.839 111.380 124.660 1.00 63.93  ? 25  GLN H N   1 
ATOM 825  C CA  . GLN B 2 9   ? 124.108 110.668 124.602 1.00 63.93  ? 25  GLN H CA  1 
ATOM 826  C C   . GLN B 2 9   ? 124.639 110.380 126.001 1.00 63.93  ? 25  GLN H C   1 
ATOM 827  O O   . GLN B 2 9   ? 125.249 111.259 126.618 1.00 63.93  ? 25  GLN H O   1 
ATOM 828  C CB  . GLN B 2 9   ? 125.121 111.474 123.789 1.00 63.93  ? 25  GLN H CB  1 
ATOM 829  C CG  . GLN B 2 9   ? 125.137 112.955 124.105 1.00 63.93  ? 25  GLN H CG  1 
ATOM 830  C CD  . GLN B 2 9   ? 126.422 113.616 123.677 1.00 63.93  ? 25  GLN H CD  1 
ATOM 831  O OE1 . GLN B 2 9   ? 127.479 112.991 123.660 1.00 63.93  ? 25  GLN H OE1 1 
ATOM 832  N NE2 . GLN B 2 9   ? 126.342 114.893 123.335 1.00 63.93  ? 25  GLN H NE2 1 
ATOM 833  N N   . PRO B 2 10  ? 124.548 109.111 126.455 1.00 68.48  ? 26  PRO H N   1 
ATOM 834  C CA  . PRO B 2 10  ? 124.645 108.749 127.887 1.00 68.48  ? 26  PRO H CA  1 
ATOM 835  C C   . PRO B 2 10  ? 124.934 109.821 128.936 1.00 68.48  ? 26  PRO H C   1 
ATOM 836  O O   . PRO B 2 10  ? 124.403 110.934 128.882 1.00 68.48  ? 26  PRO H O   1 
ATOM 837  C CB  . PRO B 2 10  ? 125.757 107.694 127.874 1.00 68.48  ? 26  PRO H CB  1 
ATOM 838  C CG  . PRO B 2 10  ? 125.528 106.994 126.575 1.00 68.48  ? 26  PRO H CG  1 
ATOM 839  C CD  . PRO B 2 10  ? 125.083 108.044 125.593 1.00 68.48  ? 26  PRO H CD  1 
ATOM 840  N N   . GLY B 2 11  ? 125.664 109.442 129.981 1.00 68.91  ? 27  GLY H N   1 
ATOM 841  C CA  . GLY B 2 11  ? 126.072 110.417 130.972 1.00 68.91  ? 27  GLY H CA  1 
ATOM 842  C C   . GLY B 2 11  ? 127.546 110.442 131.318 1.00 68.91  ? 27  GLY H C   1 
ATOM 843  O O   . GLY B 2 11  ? 128.078 111.490 131.695 1.00 68.91  ? 27  GLY H O   1 
ATOM 844  N N   . THR B 2 12  ? 128.221 109.302 131.186 1.00 70.77  ? 28  THR H N   1 
ATOM 845  C CA  . THR B 2 12  ? 129.576 109.151 131.703 1.00 70.77  ? 28  THR H CA  1 
ATOM 846  C C   . THR B 2 12  ? 130.178 107.873 131.140 1.00 70.77  ? 28  THR H C   1 
ATOM 847  O O   . THR B 2 12  ? 129.486 106.864 130.986 1.00 70.77  ? 28  THR H O   1 
ATOM 848  C CB  . THR B 2 12  ? 129.597 109.114 133.241 1.00 70.77  ? 28  THR H CB  1 
ATOM 849  O OG1 . THR B 2 12  ? 129.020 110.314 133.769 1.00 70.77  ? 28  THR H OG1 1 
ATOM 850  C CG2 . THR B 2 12  ? 131.020 108.983 133.767 1.00 70.77  ? 28  THR H CG2 1 
ATOM 851  N N   . GLU B 2 13  ? 131.473 107.927 130.835 1.00 73.93  ? 29  GLU H N   1 
ATOM 852  C CA  . GLU B 2 13  ? 132.193 106.754 130.369 1.00 73.93  ? 29  GLU H CA  1 
ATOM 853  C C   . GLU B 2 13  ? 133.614 106.791 130.913 1.00 73.93  ? 29  GLU H C   1 
ATOM 854  O O   . GLU B 2 13  ? 134.200 107.859 131.108 1.00 73.93  ? 29  GLU H O   1 
ATOM 855  C CB  . GLU B 2 13  ? 132.191 106.674 128.838 1.00 73.93  ? 29  GLU H CB  1 
ATOM 856  C CG  . GLU B 2 13  ? 130.923 106.058 128.265 1.00 73.93  ? 29  GLU H CG  1 
ATOM 857  C CD  . GLU B 2 13  ? 130.903 106.059 126.752 1.00 73.93  ? 29  GLU H CD  1 
ATOM 858  O OE1 . GLU B 2 13  ? 131.990 106.060 126.142 1.00 73.93  ? 29  GLU H OE1 1 
ATOM 859  O OE2 . GLU B 2 13  ? 129.798 106.061 126.171 1.00 73.93  ? 29  GLU H OE2 1 
ATOM 860  N N   . LEU B 2 14  ? 134.164 105.602 131.152 1.00 76.53  ? 30  LEU H N   1 
ATOM 861  C CA  . LEU B 2 14  ? 135.487 105.450 131.739 1.00 76.53  ? 30  LEU H CA  1 
ATOM 862  C C   . LEU B 2 14  ? 136.204 104.329 131.003 1.00 76.53  ? 30  LEU H C   1 
ATOM 863  O O   . LEU B 2 14  ? 135.622 103.266 130.770 1.00 76.53  ? 30  LEU H O   1 
ATOM 864  C CB  . LEU B 2 14  ? 135.387 105.145 133.239 1.00 76.53  ? 30  LEU H CB  1 
ATOM 865  C CG  . LEU B 2 14  ? 136.634 104.722 134.017 1.00 76.53  ? 30  LEU H CG  1 
ATOM 866  C CD1 . LEU B 2 14  ? 137.809 105.640 133.723 1.00 76.53  ? 30  LEU H CD1 1 
ATOM 867  C CD2 . LEU B 2 14  ? 136.335 104.692 135.506 1.00 76.53  ? 30  LEU H CD2 1 
ATOM 868  N N   . VAL B 2 15  ? 137.465 104.564 130.637 1.00 77.21  ? 31  VAL H N   1 
ATOM 869  C CA  . VAL B 2 15  ? 138.156 103.637 129.746 1.00 77.21  ? 31  VAL H CA  1 
ATOM 870  C C   . VAL B 2 15  ? 139.374 102.987 130.404 1.00 77.21  ? 31  VAL H C   1 
ATOM 871  O O   . VAL B 2 15  ? 139.374 101.771 130.610 1.00 77.21  ? 31  VAL H O   1 
ATOM 872  C CB  . VAL B 2 15  ? 138.503 104.334 128.410 1.00 77.21  ? 31  VAL H CB  1 
ATOM 873  C CG1 . VAL B 2 15  ? 137.259 104.947 127.831 1.00 77.21  ? 31  VAL H CG1 1 
ATOM 874  C CG2 . VAL B 2 15  ? 139.516 105.454 128.578 1.00 77.21  ? 31  VAL H CG2 1 
ATOM 875  N N   . LYS B 2 16  ? 140.371 103.803 130.802 1.00 77.06  ? 32  LYS H N   1 
ATOM 876  C CA  . LYS B 2 16  ? 141.772 103.629 131.211 1.00 77.06  ? 32  LYS H CA  1 
ATOM 877  C C   . LYS B 2 16  ? 142.607 103.881 129.960 1.00 77.06  ? 32  LYS H C   1 
ATOM 878  O O   . LYS B 2 16  ? 142.163 103.552 128.854 1.00 77.06  ? 32  LYS H O   1 
ATOM 879  C CB  . LYS B 2 16  ? 142.133 102.257 131.805 1.00 77.06  ? 32  LYS H CB  1 
ATOM 880  C CG  . LYS B 2 16  ? 142.049 101.039 130.898 1.00 77.06  ? 32  LYS H CG  1 
ATOM 881  C CD  . LYS B 2 16  ? 142.827 99.875  131.485 1.00 77.06  ? 32  LYS H CD  1 
ATOM 882  C CE  . LYS B 2 16  ? 142.428 99.626  132.930 1.00 77.06  ? 32  LYS H CE  1 
ATOM 883  N NZ  . LYS B 2 16  ? 140.997 99.238  133.053 1.00 77.06  ? 32  LYS H NZ  1 
ATOM 884  N N   . PRO B 2 17  ? 143.805 104.458 130.080 1.00 74.04  ? 33  PRO H N   1 
ATOM 885  C CA  . PRO B 2 17  ? 144.560 104.834 128.876 1.00 74.04  ? 33  PRO H CA  1 
ATOM 886  C C   . PRO B 2 17  ? 144.925 103.615 128.043 1.00 74.04  ? 33  PRO H C   1 
ATOM 887  O O   . PRO B 2 17  ? 145.249 102.553 128.577 1.00 74.04  ? 33  PRO H O   1 
ATOM 888  C CB  . PRO B 2 17  ? 145.806 105.536 129.429 1.00 74.04  ? 33  PRO H CB  1 
ATOM 889  C CG  . PRO B 2 17  ? 145.912 105.132 130.841 1.00 74.04  ? 33  PRO H CG  1 
ATOM 890  C CD  . PRO B 2 17  ? 144.595 104.606 131.314 1.00 74.04  ? 33  PRO H CD  1 
ATOM 891  N N   . GLY B 2 18  ? 144.870 103.781 126.724 1.00 70.47  ? 34  GLY H N   1 
ATOM 892  C CA  . GLY B 2 18  ? 145.149 102.699 125.802 1.00 70.47  ? 34  GLY H CA  1 
ATOM 893  C C   . GLY B 2 18  ? 143.912 102.216 125.074 1.00 70.47  ? 34  GLY H C   1 
ATOM 894  O O   . GLY B 2 18  ? 143.955 101.955 123.868 1.00 70.47  ? 34  GLY H O   1 
ATOM 895  N N   . ALA B 2 19  ? 142.798 102.105 125.792 1.00 71.62  ? 35  ALA H N   1 
ATOM 896  C CA  . ALA B 2 19  ? 141.556 101.629 125.209 1.00 71.62  ? 35  ALA H CA  1 
ATOM 897  C C   . ALA B 2 19  ? 140.921 102.720 124.349 1.00 71.62  ? 35  ALA H C   1 
ATOM 898  O O   . ALA B 2 19  ? 141.425 103.841 124.243 1.00 71.62  ? 35  ALA H O   1 
ATOM 899  C CB  . ALA B 2 19  ? 140.600 101.164 126.304 1.00 71.62  ? 35  ALA H CB  1 
ATOM 900  N N   . SER B 2 20  ? 139.794 102.382 123.718 1.00 71.57  ? 36  SER H N   1 
ATOM 901  C CA  . SER B 2 20  ? 139.100 103.332 122.850 1.00 71.57  ? 36  SER H CA  1 
ATOM 902  C C   . SER B 2 20  ? 137.628 102.929 122.786 1.00 71.57  ? 36  SER H C   1 
ATOM 903  O O   . SER B 2 20  ? 137.276 101.988 122.070 1.00 71.57  ? 36  SER H O   1 
ATOM 904  C CB  . SER B 2 20  ? 139.727 103.360 121.468 1.00 71.57  ? 36  SER H CB  1 
ATOM 905  O OG  . SER B 2 20  ? 139.590 102.106 120.826 1.00 71.57  ? 36  SER H OG  1 
ATOM 906  N N   . VAL B 2 21  ? 136.785 103.644 123.528 1.00 69.86  ? 37  VAL H N   1 
ATOM 907  C CA  . VAL B 2 21  ? 135.345 103.423 123.472 1.00 69.86  ? 37  VAL H CA  1 
ATOM 908  C C   . VAL B 2 21  ? 134.751 104.376 122.448 1.00 69.86  ? 37  VAL H C   1 
ATOM 909  O O   . VAL B 2 21  ? 135.308 105.448 122.189 1.00 69.86  ? 37  VAL H O   1 
ATOM 910  C CB  . VAL B 2 21  ? 134.685 103.617 124.847 1.00 69.86  ? 37  VAL H CB  1 
ATOM 911  C CG1 . VAL B 2 21  ? 135.277 102.650 125.862 1.00 69.86  ? 37  VAL H CG1 1 
ATOM 912  C CG2 . VAL B 2 21  ? 134.837 105.056 125.301 1.00 69.86  ? 37  VAL H CG2 1 
ATOM 913  N N   . LYS B 2 22  ? 133.613 104.005 121.870 1.00 64.10  ? 38  LYS H N   1 
ATOM 914  C CA  . LYS B 2 22  ? 132.974 104.794 120.823 1.00 64.10  ? 38  LYS H CA  1 
ATOM 915  C C   . LYS B 2 22  ? 131.717 105.447 121.389 1.00 64.10  ? 38  LYS H C   1 
ATOM 916  O O   . LYS B 2 22  ? 130.791 104.761 121.832 1.00 64.10  ? 38  LYS H O   1 
ATOM 917  C CB  . LYS B 2 22  ? 132.686 103.927 119.593 1.00 64.10  ? 38  LYS H CB  1 
ATOM 918  C CG  . LYS B 2 22  ? 131.655 102.824 119.766 1.00 64.10  ? 38  LYS H CG  1 
ATOM 919  C CD  . LYS B 2 22  ? 131.551 101.984 118.505 1.00 64.10  ? 38  LYS H CD  1 
ATOM 920  C CE  . LYS B 2 22  ? 130.879 102.746 117.381 1.00 64.10  ? 38  LYS H CE  1 
ATOM 921  N NZ  . LYS B 2 22  ? 130.684 101.896 116.175 1.00 64.10  ? 38  LYS H NZ  1 
ATOM 922  N N   . LEU B 2 23  ? 131.711 106.777 121.407 1.00 60.49  ? 39  LEU H N   1 
ATOM 923  C CA  . LEU B 2 23  ? 130.570 107.526 121.907 1.00 60.49  ? 39  LEU H CA  1 
ATOM 924  C C   . LEU B 2 23  ? 129.413 107.446 120.922 1.00 60.49  ? 39  LEU H C   1 
ATOM 925  O O   . LEU B 2 23  ? 129.614 107.440 119.704 1.00 60.49  ? 39  LEU H O   1 
ATOM 926  C CB  . LEU B 2 23  ? 130.957 108.985 122.133 1.00 60.49  ? 39  LEU H CB  1 
ATOM 927  C CG  . LEU B 2 23  ? 132.232 109.228 122.936 1.00 60.49  ? 39  LEU H CG  1 
ATOM 928  C CD1 . LEU B 2 23  ? 132.673 110.673 122.806 1.00 60.49  ? 39  LEU H CD1 1 
ATOM 929  C CD2 . LEU B 2 23  ? 132.019 108.862 124.391 1.00 60.49  ? 39  LEU H CD2 1 
ATOM 930  N N   . SER B 2 24  ? 128.198 107.398 121.457 1.00 61.14  ? 40  SER H N   1 
ATOM 931  C CA  . SER B 2 24  ? 126.987 107.323 120.656 1.00 61.14  ? 40  SER H CA  1 
ATOM 932  C C   . SER B 2 24  ? 126.096 108.518 120.959 1.00 61.14  ? 40  SER H C   1 
ATOM 933  O O   . SER B 2 24  ? 126.081 109.034 122.078 1.00 61.14  ? 40  SER H O   1 
ATOM 934  C CB  . SER B 2 24  ? 126.218 106.026 120.924 1.00 61.14  ? 40  SER H CB  1 
ATOM 935  O OG  . SER B 2 24  ? 125.882 105.906 122.294 1.00 61.14  ? 40  SER H OG  1 
ATOM 936  N N   . CYS B 2 25  ? 125.354 108.951 119.944 1.00 59.29  ? 41  CYS H N   1 
ATOM 937  C CA  . CYS B 2 25  ? 124.438 110.079 120.083 1.00 59.29  ? 41  CYS H CA  1 
ATOM 938  C C   . CYS B 2 25  ? 123.191 109.748 119.278 1.00 59.29  ? 41  CYS H C   1 
ATOM 939  O O   . CYS B 2 25  ? 123.261 109.638 118.050 1.00 59.29  ? 41  CYS H O   1 
ATOM 940  C CB  . CYS B 2 25  ? 125.086 111.372 119.598 1.00 59.29  ? 41  CYS H CB  1 
ATOM 941  S SG  . CYS B 2 25  ? 124.013 112.819 119.585 1.00 59.29  ? 41  CYS H SG  1 
ATOM 942  N N   . LYS B 2 26  ? 122.064 109.566 119.961 1.00 61.09  ? 42  LYS H N   1 
ATOM 943  C CA  . LYS B 2 26  ? 120.818 109.184 119.313 1.00 61.09  ? 42  LYS H CA  1 
ATOM 944  C C   . LYS B 2 26  ? 119.910 110.397 119.197 1.00 61.09  ? 42  LYS H C   1 
ATOM 945  O O   . LYS B 2 26  ? 119.680 111.105 120.183 1.00 61.09  ? 42  LYS H O   1 
ATOM 946  C CB  . LYS B 2 26  ? 120.110 108.070 120.082 1.00 61.09  ? 42  LYS H CB  1 
ATOM 947  C CG  . LYS B 2 26  ? 118.847 107.584 119.396 1.00 61.09  ? 42  LYS H CG  1 
ATOM 948  C CD  . LYS B 2 26  ? 118.419 106.219 119.896 1.00 61.09  ? 42  LYS H CD  1 
ATOM 949  C CE  . LYS B 2 26  ? 116.919 106.035 119.752 1.00 61.09  ? 42  LYS H CE  1 
ATOM 950  N NZ  . LYS B 2 26  ? 116.495 106.080 118.326 1.00 61.09  ? 42  LYS H NZ  1 
ATOM 951  N N   . ALA B 2 27  ? 119.391 110.626 117.997 1.00 60.13  ? 43  ALA H N   1 
ATOM 952  C CA  . ALA B 2 27  ? 118.566 111.785 117.697 1.00 60.13  ? 43  ALA H CA  1 
ATOM 953  C C   . ALA B 2 27  ? 117.157 111.327 117.355 1.00 60.13  ? 43  ALA H C   1 
ATOM 954  O O   . ALA B 2 27  ? 116.978 110.427 116.529 1.00 60.13  ? 43  ALA H O   1 
ATOM 955  C CB  . ALA B 2 27  ? 119.161 112.585 116.539 1.00 60.13  ? 43  ALA H CB  1 
ATOM 956  N N   . SER B 2 28  ? 116.163 111.943 117.989 1.00 58.83  ? 44  SER H N   1 
ATOM 957  C CA  . SER B 2 28  ? 114.773 111.557 117.796 1.00 58.83  ? 44  SER H CA  1 
ATOM 958  C C   . SER B 2 28  ? 113.918 112.791 117.561 1.00 58.83  ? 44  SER H C   1 
ATOM 959  O O   . SER B 2 28  ? 114.018 113.772 118.304 1.00 58.83  ? 44  SER H O   1 
ATOM 960  C CB  . SER B 2 28  ? 114.246 110.777 119.004 1.00 58.83  ? 44  SER H CB  1 
ATOM 961  O OG  . SER B 2 28  ? 114.364 111.540 120.191 1.00 58.83  ? 44  SER H OG  1 
ATOM 962  N N   . GLY B 2 29  ? 113.080 112.734 116.526 1.00 58.88  ? 45  GLY H N   1 
ATOM 963  C CA  . GLY B 2 29  ? 112.048 113.727 116.304 1.00 58.88  ? 45  GLY H CA  1 
ATOM 964  C C   . GLY B 2 29  ? 112.210 114.610 115.086 1.00 58.88  ? 45  GLY H C   1 
ATOM 965  O O   . GLY B 2 29  ? 111.384 115.511 114.899 1.00 58.88  ? 45  GLY H O   1 
ATOM 966  N N   . TYR B 2 30  ? 113.235 114.411 114.250 1.00 57.09  ? 46  TYR H N   1 
ATOM 967  C CA  . TYR B 2 30  ? 113.392 115.311 113.113 1.00 57.09  ? 46  TYR H CA  1 
ATOM 968  C C   . TYR B 2 30  ? 113.847 114.605 111.837 1.00 57.09  ? 46  TYR H C   1 
ATOM 969  O O   . TYR B 2 30  ? 114.481 115.232 110.982 1.00 57.09  ? 46  TYR H O   1 
ATOM 970  C CB  . TYR B 2 30  ? 114.354 116.454 113.453 1.00 57.09  ? 46  TYR H CB  1 
ATOM 971  C CG  . TYR B 2 30  ? 115.787 116.037 113.686 1.00 57.09  ? 46  TYR H CG  1 
ATOM 972  C CD1 . TYR B 2 30  ? 116.202 115.593 114.928 1.00 57.09  ? 46  TYR H CD1 1 
ATOM 973  C CD2 . TYR B 2 30  ? 116.730 116.115 112.672 1.00 57.09  ? 46  TYR H CD2 1 
ATOM 974  C CE1 . TYR B 2 30  ? 117.506 115.224 115.149 1.00 57.09  ? 46  TYR H CE1 1 
ATOM 975  C CE2 . TYR B 2 30  ? 118.035 115.742 112.882 1.00 57.09  ? 46  TYR H CE2 1 
ATOM 976  C CZ  . TYR B 2 30  ? 118.419 115.299 114.123 1.00 57.09  ? 46  TYR H CZ  1 
ATOM 977  O OH  . TYR B 2 30  ? 119.725 114.930 114.336 1.00 57.09  ? 46  TYR H OH  1 
ATOM 978  N N   . THR B 2 31  ? 113.511 113.324 111.663 1.00 53.16  ? 47  THR H N   1 
ATOM 979  C CA  . THR B 2 31  ? 113.823 112.591 110.431 1.00 53.16  ? 47  THR H CA  1 
ATOM 980  C C   . THR B 2 31  ? 115.331 112.602 110.160 1.00 53.16  ? 47  THR H C   1 
ATOM 981  O O   . THR B 2 31  ? 115.828 113.256 109.243 1.00 53.16  ? 47  THR H O   1 
ATOM 982  C CB  . THR B 2 31  ? 113.047 113.142 109.227 1.00 53.16  ? 47  THR H CB  1 
ATOM 983  O OG1 . THR B 2 31  ? 113.471 114.481 108.946 1.00 53.16  ? 47  THR H OG1 1 
ATOM 984  C CG2 . THR B 2 31  ? 111.556 113.134 109.510 1.00 53.16  ? 47  THR H CG2 1 
ATOM 985  N N   . PHE B 2 32  ? 116.039 111.855 111.010 1.00 51.71  ? 48  PHE H N   1 
ATOM 986  C CA  . PHE B 2 32  ? 117.494 111.866 111.149 1.00 51.71  ? 48  PHE H CA  1 
ATOM 987  C C   . PHE B 2 32  ? 118.266 112.125 109.861 1.00 51.71  ? 48  PHE H C   1 
ATOM 988  O O   . PHE B 2 32  ? 119.202 112.928 109.857 1.00 51.71  ? 48  PHE H O   1 
ATOM 989  C CB  . PHE B 2 32  ? 117.953 110.529 111.732 1.00 51.71  ? 48  PHE H CB  1 
ATOM 990  C CG  . PHE B 2 32  ? 119.440 110.409 111.885 1.00 51.71  ? 48  PHE H CG  1 
ATOM 991  C CD1 . PHE B 2 32  ? 120.151 111.333 112.626 1.00 51.71  ? 48  PHE H CD1 1 
ATOM 992  C CD2 . PHE B 2 32  ? 120.126 109.373 111.279 1.00 51.71  ? 48  PHE H CD2 1 
ATOM 993  C CE1 . PHE B 2 32  ? 121.518 111.219 112.767 1.00 51.71  ? 48  PHE H CE1 1 
ATOM 994  C CE2 . PHE B 2 32  ? 121.491 109.256 111.415 1.00 51.71  ? 48  PHE H CE2 1 
ATOM 995  C CZ  . PHE B 2 32  ? 122.188 110.179 112.158 1.00 51.71  ? 48  PHE H CZ  1 
ATOM 996  N N   . THR B 2 33  ? 117.892 111.466 108.766 1.00 50.16  ? 49  THR H N   1 
ATOM 997  C CA  . THR B 2 33  ? 118.677 111.580 107.543 1.00 50.16  ? 49  THR H CA  1 
ATOM 998  C C   . THR B 2 33  ? 118.344 112.845 106.764 1.00 50.16  ? 49  THR H C   1 
ATOM 999  O O   . THR B 2 33  ? 118.117 112.787 105.553 1.00 50.16  ? 49  THR H O   1 
ATOM 1000 C CB  . THR B 2 33  ? 118.454 110.360 106.649 1.00 50.16  ? 49  THR H CB  1 
ATOM 1001 O OG1 . THR B 2 33  ? 117.238 110.524 105.911 1.00 50.16  ? 49  THR H OG1 1 
ATOM 1002 C CG2 . THR B 2 33  ? 118.360 109.099 107.485 1.00 50.16  ? 49  THR H CG2 1 
ATOM 1003 N N   . SER B 2 34  ? 118.320 113.992 107.441 1.00 47.86  ? 50  SER H N   1 
ATOM 1004 C CA  . SER B 2 34  ? 118.159 115.268 106.751 1.00 47.86  ? 50  SER H CA  1 
ATOM 1005 C C   . SER B 2 34  ? 119.056 116.381 107.266 1.00 47.86  ? 50  SER H C   1 
ATOM 1006 O O   . SER B 2 34  ? 119.248 117.362 106.542 1.00 47.86  ? 50  SER H O   1 
ATOM 1007 C CB  . SER B 2 34  ? 116.704 115.739 106.829 1.00 47.86  ? 50  SER H CB  1 
ATOM 1008 O OG  . SER B 2 34  ? 115.897 115.048 105.894 1.00 47.86  ? 50  SER H OG  1 
ATOM 1009 N N   . TYR B 2 35  ? 119.631 116.269 108.461 1.00 47.96  ? 51  TYR H N   1 
ATOM 1010 C CA  . TYR B 2 35  ? 120.459 117.312 109.052 1.00 47.96  ? 51  TYR H CA  1 
ATOM 1011 C C   . TYR B 2 35  ? 121.784 116.702 109.474 1.00 47.96  ? 51  TYR H C   1 
ATOM 1012 O O   . TYR B 2 35  ? 121.804 115.635 110.094 1.00 47.96  ? 51  TYR H O   1 
ATOM 1013 C CB  . TYR B 2 35  ? 119.771 117.947 110.267 1.00 47.96  ? 51  TYR H CB  1 
ATOM 1014 C CG  . TYR B 2 35  ? 118.539 118.767 109.958 1.00 47.96  ? 51  TYR H CG  1 
ATOM 1015 C CD1 . TYR B 2 35  ? 118.266 119.194 108.671 1.00 47.96  ? 51  TYR H CD1 1 
ATOM 1016 C CD2 . TYR B 2 35  ? 117.638 119.096 110.956 1.00 47.96  ? 51  TYR H CD2 1 
ATOM 1017 C CE1 . TYR B 2 35  ? 117.141 119.938 108.388 1.00 47.96  ? 51  TYR H CE1 1 
ATOM 1018 C CE2 . TYR B 2 35  ? 116.507 119.836 110.681 1.00 47.96  ? 51  TYR H CE2 1 
ATOM 1019 C CZ  . TYR B 2 35  ? 116.265 120.256 109.396 1.00 47.96  ? 51  TYR H CZ  1 
ATOM 1020 O OH  . TYR B 2 35  ? 115.142 120.996 109.114 1.00 47.96  ? 51  TYR H OH  1 
ATOM 1021 N N   . SER B 2 36  ? 122.884 117.378 109.153 1.00 43.52  ? 52  SER H N   1 
ATOM 1022 C CA  . SER B 2 36  ? 124.196 116.874 109.524 1.00 43.52  ? 52  SER H CA  1 
ATOM 1023 C C   . SER B 2 36  ? 124.399 116.959 111.035 1.00 43.52  ? 52  SER H C   1 
ATOM 1024 O O   . SER B 2 36  ? 123.738 117.727 111.737 1.00 43.52  ? 52  SER H O   1 
ATOM 1025 C CB  . SER B 2 36  ? 125.294 117.649 108.800 1.00 43.52  ? 52  SER H CB  1 
ATOM 1026 O OG  . SER B 2 36  ? 125.045 119.040 108.840 1.00 43.52  ? 52  SER H OG  1 
ATOM 1027 N N   . VAL B 2 37  ? 125.329 116.148 111.532 1.00 44.25  ? 53  VAL H N   1 
ATOM 1028 C CA  . VAL B 2 37  ? 125.609 116.028 112.958 1.00 44.25  ? 53  VAL H CA  1 
ATOM 1029 C C   . VAL B 2 37  ? 127.063 116.406 113.198 1.00 44.25  ? 53  VAL H C   1 
ATOM 1030 O O   . VAL B 2 37  ? 127.959 115.914 112.503 1.00 44.25  ? 53  VAL H O   1 
ATOM 1031 C CB  . VAL B 2 37  ? 125.319 114.607 113.472 1.00 44.25  ? 53  VAL H CB  1 
ATOM 1032 C CG1 . VAL B 2 37  ? 125.714 114.481 114.928 1.00 44.25  ? 53  VAL H CG1 1 
ATOM 1033 C CG2 . VAL B 2 37  ? 123.854 114.270 113.286 1.00 44.25  ? 53  VAL H CG2 1 
ATOM 1034 N N   . HIS B 2 38  ? 127.297 117.268 114.185 1.00 45.41  ? 54  HIS H N   1 
ATOM 1035 C CA  . HIS B 2 38  ? 128.597 117.848 114.465 1.00 45.41  ? 54  HIS H CA  1 
ATOM 1036 C C   . HIS B 2 38  ? 129.025 117.464 115.874 1.00 45.41  ? 54  HIS H C   1 
ATOM 1037 O O   . HIS B 2 38  ? 128.191 117.344 116.777 1.00 45.41  ? 54  HIS H O   1 
ATOM 1038 C CB  . HIS B 2 38  ? 128.537 119.371 114.351 1.00 45.41  ? 54  HIS H CB  1 
ATOM 1039 C CG  . HIS B 2 38  ? 127.874 119.863 113.102 1.00 45.41  ? 54  HIS H CG  1 
ATOM 1040 N ND1 . HIS B 2 38  ? 128.524 119.944 111.891 1.00 45.41  ? 54  HIS H ND1 1 
ATOM 1041 C CD2 . HIS B 2 38  ? 126.613 120.301 112.881 1.00 45.41  ? 54  HIS H CD2 1 
ATOM 1042 C CE1 . HIS B 2 38  ? 127.693 120.412 110.977 1.00 45.41  ? 54  HIS H CE1 1 
ATOM 1043 N NE2 . HIS B 2 38  ? 126.527 120.638 111.552 1.00 45.41  ? 54  HIS H NE2 1 
ATOM 1044 N N   . TRP B 2 39  ? 130.330 117.285 116.064 1.00 50.14  ? 55  TRP H N   1 
ATOM 1045 C CA  . TRP B 2 39  ? 130.894 116.912 117.354 1.00 50.14  ? 55  TRP H CA  1 
ATOM 1046 C C   . TRP B 2 39  ? 131.830 118.002 117.854 1.00 50.14  ? 55  TRP H C   1 
ATOM 1047 O O   . TRP B 2 39  ? 132.690 118.482 117.112 1.00 50.14  ? 55  TRP H O   1 
ATOM 1048 C CB  . TRP B 2 39  ? 131.647 115.586 117.264 1.00 50.14  ? 55  TRP H CB  1 
ATOM 1049 C CG  . TRP B 2 39  ? 130.747 114.409 117.129 1.00 50.14  ? 55  TRP H CG  1 
ATOM 1050 C CD1 . TRP B 2 39  ? 130.196 113.929 115.983 1.00 50.14  ? 55  TRP H CD1 1 
ATOM 1051 C CD2 . TRP B 2 39  ? 130.285 113.561 118.184 1.00 50.14  ? 55  TRP H CD2 1 
ATOM 1052 N NE1 . TRP B 2 39  ? 129.419 112.832 116.254 1.00 50.14  ? 55  TRP H NE1 1 
ATOM 1053 C CE2 . TRP B 2 39  ? 129.457 112.586 117.601 1.00 50.14  ? 55  TRP H CE2 1 
ATOM 1054 C CE3 . TRP B 2 39  ? 130.492 113.531 119.564 1.00 50.14  ? 55  TRP H CE3 1 
ATOM 1055 C CZ2 . TRP B 2 39  ? 128.838 111.591 118.348 1.00 50.14  ? 55  TRP H CZ2 1 
ATOM 1056 C CZ3 . TRP B 2 39  ? 129.875 112.545 120.304 1.00 50.14  ? 55  TRP H CZ3 1 
ATOM 1057 C CH2 . TRP B 2 39  ? 129.060 111.588 119.696 1.00 50.14  ? 55  TRP H CH2 1 
ATOM 1058 N N   . VAL B 2 40  ? 131.663 118.383 119.119 1.00 52.10  ? 56  VAL H N   1 
ATOM 1059 C CA  . VAL B 2 40  ? 132.436 119.458 119.731 1.00 52.10  ? 56  VAL H CA  1 
ATOM 1060 C C   . VAL B 2 40  ? 133.020 118.960 121.046 1.00 52.10  ? 56  VAL H C   1 
ATOM 1061 O O   . VAL B 2 40  ? 132.326 118.315 121.839 1.00 52.10  ? 56  VAL H O   1 
ATOM 1062 C CB  . VAL B 2 40  ? 131.572 120.715 119.961 1.00 52.10  ? 56  VAL H CB  1 
ATOM 1063 C CG1 . VAL B 2 40  ? 132.371 121.788 120.667 1.00 52.10  ? 56  VAL H CG1 1 
ATOM 1064 C CG2 . VAL B 2 40  ? 131.034 121.235 118.645 1.00 52.10  ? 56  VAL H CG2 1 
ATOM 1065 N N   . LYS B 2 41  ? 134.295 119.260 121.282 1.00 56.32  ? 57  LYS H N   1 
ATOM 1066 C CA  . LYS B 2 41  ? 134.992 118.837 122.490 1.00 56.32  ? 57  LYS H CA  1 
ATOM 1067 C C   . LYS B 2 41  ? 135.313 120.050 123.348 1.00 56.32  ? 57  LYS H C   1 
ATOM 1068 O O   . LYS B 2 41  ? 135.915 121.013 122.865 1.00 56.32  ? 57  LYS H O   1 
ATOM 1069 C CB  . LYS B 2 41  ? 136.280 118.089 122.153 1.00 56.32  ? 57  LYS H CB  1 
ATOM 1070 C CG  . LYS B 2 41  ? 137.247 117.975 123.317 1.00 56.32  ? 57  LYS H CG  1 
ATOM 1071 C CD  . LYS B 2 41  ? 138.677 117.826 122.839 1.00 56.32  ? 57  LYS H CD  1 
ATOM 1072 C CE  . LYS B 2 41  ? 139.539 117.193 123.913 1.00 56.32  ? 57  LYS H CE  1 
ATOM 1073 N NZ  . LYS B 2 41  ? 140.958 117.068 123.489 1.00 56.32  ? 57  LYS H NZ  1 
ATOM 1074 N N   . GLN B 2 42  ? 134.923 119.996 124.620 1.00 63.07  ? 58  GLN H N   1 
ATOM 1075 C CA  . GLN B 2 42  ? 135.181 121.067 125.570 1.00 63.07  ? 58  GLN H CA  1 
ATOM 1076 C C   . GLN B 2 42  ? 136.040 120.545 126.708 1.00 63.07  ? 58  GLN H C   1 
ATOM 1077 O O   . GLN B 2 42  ? 135.653 119.597 127.398 1.00 63.07  ? 58  GLN H O   1 
ATOM 1078 C CB  . GLN B 2 42  ? 133.882 121.639 126.137 1.00 63.07  ? 58  GLN H CB  1 
ATOM 1079 C CG  . GLN B 2 42  ? 134.088 122.871 126.999 1.00 63.07  ? 58  GLN H CG  1 
ATOM 1080 C CD  . GLN B 2 42  ? 132.799 123.380 127.603 1.00 63.07  ? 58  GLN H CD  1 
ATOM 1081 O OE1 . GLN B 2 42  ? 132.659 124.571 127.878 1.00 63.07  ? 58  GLN H OE1 1 
ATOM 1082 N NE2 . GLN B 2 42  ? 131.851 122.479 127.821 1.00 63.07  ? 58  GLN H NE2 1 
ATOM 1083 N N   . ARG B 2 43  ? 137.189 121.177 126.912 1.00 69.96  ? 59  ARG H N   1 
ATOM 1084 C CA  . ARG B 2 43  ? 138.021 120.870 128.057 1.00 69.96  ? 59  ARG H CA  1 
ATOM 1085 C C   . ARG B 2 43  ? 137.330 121.324 129.341 1.00 69.96  ? 59  ARG H C   1 
ATOM 1086 O O   . ARG B 2 43  ? 136.423 122.157 129.306 1.00 69.96  ? 59  ARG H O   1 
ATOM 1087 C CB  . ARG B 2 43  ? 139.378 121.549 127.913 1.00 69.96  ? 59  ARG H CB  1 
ATOM 1088 C CG  . ARG B 2 43  ? 140.340 120.822 126.998 1.00 69.96  ? 59  ARG H CG  1 
ATOM 1089 C CD  . ARG B 2 43  ? 141.035 119.698 127.742 1.00 69.96  ? 59  ARG H CD  1 
ATOM 1090 N NE  . ARG B 2 43  ? 142.069 119.068 126.932 1.00 69.96  ? 59  ARG H NE  1 
ATOM 1091 C CZ  . ARG B 2 43  ? 142.887 118.122 127.371 1.00 69.96  ? 59  ARG H CZ  1 
ATOM 1092 N NH1 . ARG B 2 43  ? 142.828 117.681 128.617 1.00 69.96  ? 59  ARG H NH1 1 
ATOM 1093 N NH2 . ARG B 2 43  ? 143.786 117.605 126.539 1.00 69.96  ? 59  ARG H NH2 1 
ATOM 1094 N N   . PRO B 2 44  ? 137.727 120.767 130.489 1.00 71.09  ? 60  PRO H N   1 
ATOM 1095 C CA  . PRO B 2 44  ? 137.093 121.187 131.751 1.00 71.09  ? 60  PRO H CA  1 
ATOM 1096 C C   . PRO B 2 44  ? 137.215 122.676 132.035 1.00 71.09  ? 60  PRO H C   1 
ATOM 1097 O O   . PRO B 2 44  ? 136.322 123.251 132.669 1.00 71.09  ? 60  PRO H O   1 
ATOM 1098 C CB  . PRO B 2 44  ? 137.828 120.345 132.802 1.00 71.09  ? 60  PRO H CB  1 
ATOM 1099 C CG  . PRO B 2 44  ? 138.272 119.135 132.064 1.00 71.09  ? 60  PRO H CG  1 
ATOM 1100 C CD  . PRO B 2 44  ? 138.607 119.600 130.676 1.00 71.09  ? 60  PRO H CD  1 
ATOM 1101 N N   . GLY B 2 45  ? 138.289 123.321 131.587 1.00 70.53  ? 61  GLY H N   1 
ATOM 1102 C CA  . GLY B 2 45  ? 138.461 124.735 131.859 1.00 70.53  ? 61  GLY H CA  1 
ATOM 1103 C C   . GLY B 2 45  ? 138.951 125.562 130.687 1.00 70.53  ? 61  GLY H C   1 
ATOM 1104 O O   . GLY B 2 45  ? 139.565 126.615 130.884 1.00 70.53  ? 61  GLY H O   1 
ATOM 1105 N N   . GLN B 2 46  ? 138.691 125.103 129.464 1.00 71.59  ? 62  GLN H N   1 
ATOM 1106 C CA  . GLN B 2 46  ? 139.080 125.825 128.260 1.00 71.59  ? 62  GLN H CA  1 
ATOM 1107 C C   . GLN B 2 46  ? 137.938 125.777 127.252 1.00 71.59  ? 62  GLN H C   1 
ATOM 1108 O O   . GLN B 2 46  ? 136.848 125.271 127.536 1.00 71.59  ? 62  GLN H O   1 
ATOM 1109 C CB  . GLN B 2 46  ? 140.382 125.268 127.666 1.00 71.59  ? 62  GLN H CB  1 
ATOM 1110 C CG  . GLN B 2 46  ? 141.625 125.487 128.527 1.00 71.59  ? 62  GLN H CG  1 
ATOM 1111 C CD  . GLN B 2 46  ? 141.786 124.468 129.638 1.00 71.59  ? 62  GLN H CD  1 
ATOM 1112 O OE1 . GLN B 2 46  ? 141.172 123.405 129.618 1.00 71.59  ? 62  GLN H OE1 1 
ATOM 1113 N NE2 . GLN B 2 46  ? 142.620 124.793 130.618 1.00 71.59  ? 62  GLN H NE2 1 
ATOM 1114 N N   . GLY B 2 47  ? 138.198 126.310 126.059 1.00 65.97  ? 63  GLY H N   1 
ATOM 1115 C CA  . GLY B 2 47  ? 137.167 126.509 125.065 1.00 65.97  ? 63  GLY H CA  1 
ATOM 1116 C C   . GLY B 2 47  ? 136.832 125.260 124.271 1.00 65.97  ? 63  GLY H C   1 
ATOM 1117 O O   . GLY B 2 47  ? 137.315 124.159 124.531 1.00 65.97  ? 63  GLY H O   1 
ATOM 1118 N N   . LEU B 2 48  ? 135.975 125.456 123.273 1.00 55.96  ? 64  LEU H N   1 
ATOM 1119 C CA  . LEU B 2 48  ? 135.464 124.383 122.437 1.00 55.96  ? 64  LEU H CA  1 
ATOM 1120 C C   . LEU B 2 48  ? 136.418 124.108 121.274 1.00 55.96  ? 64  LEU H C   1 
ATOM 1121 O O   . LEU B 2 48  ? 137.319 124.895 120.975 1.00 55.96  ? 64  LEU H O   1 
ATOM 1122 C CB  . LEU B 2 48  ? 134.066 124.743 121.944 1.00 55.96  ? 64  LEU H CB  1 
ATOM 1123 C CG  . LEU B 2 48  ? 133.143 125.177 123.084 1.00 55.96  ? 64  LEU H CG  1 
ATOM 1124 C CD1 . LEU B 2 48  ? 132.016 126.055 122.587 1.00 55.96  ? 64  LEU H CD1 1 
ATOM 1125 C CD2 . LEU B 2 48  ? 132.579 123.963 123.777 1.00 55.96  ? 64  LEU H CD2 1 
ATOM 1126 N N   . GLU B 2 49  ? 136.220 122.964 120.611 1.00 54.69  ? 65  GLU H N   1 
ATOM 1127 C CA  . GLU B 2 49  ? 137.231 122.487 119.673 1.00 54.69  ? 65  GLU H CA  1 
ATOM 1128 C C   . GLU B 2 49  ? 136.710 122.145 118.279 1.00 54.69  ? 65  GLU H C   1 
ATOM 1129 O O   . GLU B 2 49  ? 137.429 122.341 117.294 1.00 54.69  ? 65  GLU H O   1 
ATOM 1130 C CB  . GLU B 2 49  ? 137.939 121.267 120.259 1.00 54.69  ? 65  GLU H CB  1 
ATOM 1131 C CG  . GLU B 2 49  ? 139.381 121.136 119.819 1.00 54.69  ? 65  GLU H CG  1 
ATOM 1132 C CD  . GLU B 2 49  ? 140.291 122.104 120.543 1.00 54.69  ? 65  GLU H CD  1 
ATOM 1133 O OE1 . GLU B 2 49  ? 139.998 122.434 121.711 1.00 54.69  ? 65  GLU H OE1 1 
ATOM 1134 O OE2 . GLU B 2 49  ? 141.296 122.538 119.945 1.00 54.69  ? 65  GLU H OE2 1 
ATOM 1135 N N   . TRP B 2 50  ? 135.483 121.631 118.172 1.00 48.90  ? 66  TRP H N   1 
ATOM 1136 C CA  . TRP B 2 50  ? 134.923 121.161 116.900 1.00 48.90  ? 66  TRP H CA  1 
ATOM 1137 C C   . TRP B 2 50  ? 135.778 120.044 116.292 1.00 48.90  ? 66  TRP H C   1 
ATOM 1138 O O   . TRP B 2 50  ? 136.547 120.245 115.355 1.00 48.90  ? 66  TRP H O   1 
ATOM 1139 C CB  . TRP B 2 50  ? 134.732 122.290 115.882 1.00 48.90  ? 66  TRP H CB  1 
ATOM 1140 C CG  . TRP B 2 50  ? 133.992 121.790 114.676 1.00 48.90  ? 66  TRP H CG  1 
ATOM 1141 C CD1 . TRP B 2 50  ? 132.666 121.492 114.603 1.00 48.90  ? 66  TRP H CD1 1 
ATOM 1142 C CD2 . TRP B 2 50  ? 134.540 121.483 113.387 1.00 48.90  ? 66  TRP H CD2 1 
ATOM 1143 N NE1 . TRP B 2 50  ? 132.349 121.040 113.348 1.00 48.90  ? 66  TRP H NE1 1 
ATOM 1144 C CE2 . TRP B 2 50  ? 133.484 121.027 112.583 1.00 48.90  ? 66  TRP H CE2 1 
ATOM 1145 C CE3 . TRP B 2 50  ? 135.819 121.565 112.832 1.00 48.90  ? 66  TRP H CE3 1 
ATOM 1146 C CZ2 . TRP B 2 50  ? 133.666 120.650 111.259 1.00 48.90  ? 66  TRP H CZ2 1 
ATOM 1147 C CZ3 . TRP B 2 50  ? 135.996 121.191 111.520 1.00 48.90  ? 66  TRP H CZ3 1 
ATOM 1148 C CH2 . TRP B 2 50  ? 134.927 120.742 110.747 1.00 48.90  ? 66  TRP H CH2 1 
ATOM 1149 N N   . ILE B 2 51  ? 135.672 118.867 116.909 1.00 49.49  ? 67  ILE H N   1 
ATOM 1150 C CA  . ILE B 2 51  ? 136.377 117.690 116.406 1.00 49.49  ? 67  ILE H CA  1 
ATOM 1151 C C   . ILE B 2 51  ? 136.088 117.470 114.923 1.00 49.49  ? 67  ILE H C   1 
ATOM 1152 O O   . ILE B 2 51  ? 136.997 117.508 114.087 1.00 49.49  ? 67  ILE H O   1 
ATOM 1153 C CB  . ILE B 2 51  ? 136.000 116.453 117.235 1.00 49.49  ? 67  ILE H CB  1 
ATOM 1154 C CG1 . ILE B 2 51  ? 136.459 116.631 118.679 1.00 49.49  ? 67  ILE H CG1 1 
ATOM 1155 C CG2 . ILE B 2 51  ? 136.593 115.200 116.621 1.00 49.49  ? 67  ILE H CG2 1 
ATOM 1156 C CD1 . ILE B 2 51  ? 135.913 115.595 119.602 1.00 49.49  ? 67  ILE H CD1 1 
ATOM 1157 N N   . GLY B 2 52  ? 134.827 117.241 114.574 1.00 47.89  ? 68  GLY H N   1 
ATOM 1158 C CA  . GLY B 2 52  ? 134.489 116.961 113.189 1.00 47.89  ? 68  GLY H CA  1 
ATOM 1159 C C   . GLY B 2 52  ? 132.996 116.792 113.029 1.00 47.89  ? 68  GLY H C   1 
ATOM 1160 O O   . GLY B 2 52  ? 132.223 116.960 113.977 1.00 47.89  ? 68  GLY H O   1 
ATOM 1161 N N   . SER B 2 53  ? 132.592 116.446 111.807 1.00 46.75  ? 69  SER H N   1 
ATOM 1162 C CA  . SER B 2 53  ? 131.172 116.318 111.511 1.00 46.75  ? 69  SER H CA  1 
ATOM 1163 C C   . SER B 2 53  ? 130.963 115.557 110.212 1.00 46.75  ? 69  SER H C   1 
ATOM 1164 O O   . SER B 2 53  ? 131.810 115.586 109.317 1.00 46.75  ? 69  SER H O   1 
ATOM 1165 C CB  . SER B 2 53  ? 130.510 117.689 111.405 1.00 46.75  ? 69  SER H CB  1 
ATOM 1166 O OG  . SER B 2 53  ? 130.981 118.393 110.271 1.00 46.75  ? 69  SER H OG  1 
ATOM 1167 N N   . ILE B 2 54  ? 129.813 114.885 110.119 1.00 44.75  ? 70  ILE H N   1 
ATOM 1168 C CA  . ILE B 2 54  ? 129.365 114.217 108.902 1.00 44.75  ? 70  ILE H CA  1 
ATOM 1169 C C   . ILE B 2 54  ? 127.867 114.445 108.749 1.00 44.75  ? 70  ILE H C   1 
ATOM 1170 O O   . ILE B 2 54  ? 127.176 114.830 109.693 1.00 44.75  ? 70  ILE H O   1 
ATOM 1171 C CB  . ILE B 2 54  ? 129.665 112.704 108.906 1.00 44.75  ? 70  ILE H CB  1 
ATOM 1172 C CG1 . ILE B 2 54  ? 128.991 112.025 110.088 1.00 44.75  ? 70  ILE H CG1 1 
ATOM 1173 C CG2 . ILE B 2 54  ? 131.148 112.436 108.965 1.00 44.75  ? 70  ILE H CG2 1 
ATOM 1174 C CD1 . ILE B 2 54  ? 129.055 110.536 109.993 1.00 44.75  ? 70  ILE H CD1 1 
ATOM 1175 N N   . ASN B 2 55  ? 127.365 114.201 107.536 1.00 43.24  ? 71  ASN H N   1 
ATOM 1176 C CA  . ASN B 2 55  ? 125.922 114.216 107.366 1.00 43.24  ? 71  ASN H CA  1 
ATOM 1177 C C   . ASN B 2 55  ? 125.385 112.800 107.159 1.00 43.24  ? 71  ASN H C   1 
ATOM 1178 O O   . ASN B 2 55  ? 126.088 111.930 106.638 1.00 43.24  ? 71  ASN H O   1 
ATOM 1179 C CB  . ASN B 2 55  ? 125.485 115.125 106.207 1.00 43.24  ? 71  ASN H CB  1 
ATOM 1180 C CG  . ASN B 2 55  ? 126.021 114.687 104.864 1.00 43.24  ? 71  ASN H CG  1 
ATOM 1181 O OD1 . ASN B 2 55  ? 126.655 113.646 104.736 1.00 43.24  ? 71  ASN H OD1 1 
ATOM 1182 N ND2 . ASN B 2 55  ? 125.754 115.489 103.843 1.00 43.24  ? 71  ASN H ND2 1 
ATOM 1183 N N   . PRO B 2 56  ? 124.154 112.530 107.601 1.00 44.98  ? 72  PRO H N   1 
ATOM 1184 C CA  . PRO B 2 56  ? 123.657 111.144 107.577 1.00 44.98  ? 72  PRO H CA  1 
ATOM 1185 C C   . PRO B 2 56  ? 123.610 110.514 106.197 1.00 44.98  ? 72  PRO H C   1 
ATOM 1186 O O   . PRO B 2 56  ? 123.891 109.317 106.067 1.00 44.98  ? 72  PRO H O   1 
ATOM 1187 C CB  . PRO B 2 56  ? 122.257 111.277 108.185 1.00 44.98  ? 72  PRO H CB  1 
ATOM 1188 C CG  . PRO B 2 56  ? 122.342 112.483 109.043 1.00 44.98  ? 72  PRO H CG  1 
ATOM 1189 C CD  . PRO B 2 56  ? 123.239 113.428 108.319 1.00 44.98  ? 72  PRO H CD  1 
ATOM 1190 N N   . ASN B 2 57  ? 123.261 111.270 105.163 1.00 45.18  ? 73  ASN H N   1 
ATOM 1191 C CA  . ASN B 2 57  ? 123.169 110.736 103.812 1.00 45.18  ? 73  ASN H CA  1 
ATOM 1192 C C   . ASN B 2 57  ? 124.332 111.248 102.975 1.00 45.18  ? 73  ASN H C   1 
ATOM 1193 O O   . ASN B 2 57  ? 124.707 112.418 103.072 1.00 45.18  ? 73  ASN H O   1 
ATOM 1194 C CB  . ASN B 2 57  ? 121.837 111.104 103.153 1.00 45.18  ? 73  ASN H CB  1 
ATOM 1195 C CG  . ASN B 2 57  ? 121.629 112.595 103.049 1.00 45.18  ? 73  ASN H CG  1 
ATOM 1196 O OD1 . ASN B 2 57  ? 122.156 113.365 103.849 1.00 45.18  ? 73  ASN H OD1 1 
ATOM 1197 N ND2 . ASN B 2 57  ? 120.861 113.014 102.052 1.00 45.18  ? 73  ASN H ND2 1 
ATOM 1198 N N   . ASN B 2 58  ? 124.893 110.350 102.166 1.00 42.93  ? 74  ASN H N   1 
ATOM 1199 C CA  . ASN B 2 58  ? 126.063 110.442 101.298 1.00 42.93  ? 74  ASN H CA  1 
ATOM 1200 C C   . ASN B 2 58  ? 127.377 110.397 102.081 1.00 42.93  ? 74  ASN H C   1 
ATOM 1201 O O   . ASN B 2 58  ? 128.435 110.289 101.462 1.00 42.93  ? 74  ASN H O   1 
ATOM 1202 C CB  . ASN B 2 58  ? 126.042 111.666 100.350 1.00 42.93  ? 74  ASN H CB  1 
ATOM 1203 C CG  . ASN B 2 58  ? 126.480 112.986 101.000 1.00 42.93  ? 74  ASN H CG  1 
ATOM 1204 O OD1 . ASN B 2 58  ? 127.089 113.029 102.064 1.00 42.93  ? 74  ASN H OD1 1 
ATOM 1205 N ND2 . ASN B 2 58  ? 126.145 114.084 100.337 1.00 42.93  ? 74  ASN H ND2 1 
ATOM 1206 N N   . ASP B 2 59  ? 127.344 110.461 103.412 1.00 44.72  ? 75  ASP H N   1 
ATOM 1207 C CA  . ASP B 2 59  ? 128.487 110.151 104.273 1.00 44.72  ? 75  ASP H CA  1 
ATOM 1208 C C   . ASP B 2 59  ? 129.757 110.896 103.863 1.00 44.72  ? 75  ASP H C   1 
ATOM 1209 O O   . ASP B 2 59  ? 130.808 110.297 103.629 1.00 44.72  ? 75  ASP H O   1 
ATOM 1210 C CB  . ASP B 2 59  ? 128.737 108.645 104.307 1.00 44.72  ? 75  ASP H CB  1 
ATOM 1211 C CG  . ASP B 2 59  ? 127.513 107.866 104.722 1.00 44.72  ? 75  ASP H CG  1 
ATOM 1212 O OD1 . ASP B 2 59  ? 126.489 108.501 105.043 1.00 44.72  ? 75  ASP H OD1 1 
ATOM 1213 O OD2 . ASP B 2 59  ? 127.571 106.620 104.726 1.00 44.72  ? 75  ASP H OD2 1 
ATOM 1214 N N   . VAL B 2 60  ? 129.662 112.211 103.774 1.00 42.40  ? 76  VAL H N   1 
ATOM 1215 C CA  . VAL B 2 60  ? 130.844 113.042 103.586 1.00 42.40  ? 76  VAL H CA  1 
ATOM 1216 C C   . VAL B 2 60  ? 131.327 113.517 104.947 1.00 42.40  ? 76  VAL H C   1 
ATOM 1217 O O   . VAL B 2 60  ? 130.532 113.920 105.803 1.00 42.40  ? 76  VAL H O   1 
ATOM 1218 C CB  . VAL B 2 60  ? 130.559 114.221 102.635 1.00 42.40  ? 76  VAL H CB  1 
ATOM 1219 C CG1 . VAL B 2 60  ? 130.177 113.702 101.266 1.00 42.40  ? 76  VAL H CG1 1 
ATOM 1220 C CG2 . VAL B 2 60  ? 129.459 115.108 103.186 1.00 42.40  ? 76  VAL H CG2 1 
ATOM 1221 N N   . ALA B 2 61  ? 132.636 113.445 105.162 1.00 43.72  ? 77  ALA H N   1 
ATOM 1222 C CA  . ALA B 2 61  ? 133.232 113.717 106.460 1.00 43.72  ? 77  ALA H CA  1 
ATOM 1223 C C   . ALA B 2 61  ? 134.067 114.987 106.414 1.00 43.72  ? 77  ALA H C   1 
ATOM 1224 O O   . ALA B 2 61  ? 134.893 115.169 105.515 1.00 43.72  ? 77  ALA H O   1 
ATOM 1225 C CB  . ALA B 2 61  ? 134.102 112.545 106.917 1.00 43.72  ? 77  ALA H CB  1 
ATOM 1226 N N   . TYR B 2 62  ? 133.845 115.860 107.390 1.00 45.81  ? 78  TYR H N   1 
ATOM 1227 C CA  . TYR B 2 62  ? 134.639 117.064 107.578 1.00 45.81  ? 78  TYR H CA  1 
ATOM 1228 C C   . TYR B 2 62  ? 135.411 116.920 108.879 1.00 45.81  ? 78  TYR H C   1 
ATOM 1229 O O   . TYR B 2 62  ? 134.813 116.693 109.935 1.00 45.81  ? 78  TYR H O   1 
ATOM 1230 C CB  . TYR B 2 62  ? 133.754 118.310 107.616 1.00 45.81  ? 78  TYR H CB  1 
ATOM 1231 C CG  . TYR B 2 62  ? 133.070 118.618 106.308 1.00 45.81  ? 78  TYR H CG  1 
ATOM 1232 C CD1 . TYR B 2 62  ? 133.559 118.119 105.113 1.00 45.81  ? 78  TYR H CD1 1 
ATOM 1233 C CD2 . TYR B 2 62  ? 131.932 119.409 106.269 1.00 45.81  ? 78  TYR H CD2 1 
ATOM 1234 C CE1 . TYR B 2 62  ? 132.936 118.398 103.916 1.00 45.81  ? 78  TYR H CE1 1 
ATOM 1235 C CE2 . TYR B 2 62  ? 131.304 119.694 105.078 1.00 45.81  ? 78  TYR H CE2 1 
ATOM 1236 C CZ  . TYR B 2 62  ? 131.810 119.187 103.904 1.00 45.81  ? 78  TYR H CZ  1 
ATOM 1237 O OH  . TYR B 2 62  ? 131.184 119.469 102.713 1.00 45.81  ? 78  TYR H OH  1 
ATOM 1238 N N   . PHE B 2 63  ? 136.730 117.054 108.807 1.00 50.20  ? 79  PHE H N   1 
ATOM 1239 C CA  . PHE B 2 63  ? 137.592 116.785 109.946 1.00 50.20  ? 79  PHE H CA  1 
ATOM 1240 C C   . PHE B 2 63  ? 138.429 118.007 110.284 1.00 50.20  ? 79  PHE H C   1 
ATOM 1241 O O   . PHE B 2 63  ? 138.787 118.805 109.416 1.00 50.20  ? 79  PHE H O   1 
ATOM 1242 C CB  . PHE B 2 63  ? 138.527 115.601 109.678 1.00 50.20  ? 79  PHE H CB  1 
ATOM 1243 C CG  . PHE B 2 63  ? 137.934 114.272 110.019 1.00 50.20  ? 79  PHE H CG  1 
ATOM 1244 C CD1 . PHE B 2 63  ? 137.680 113.932 111.334 1.00 50.20  ? 79  PHE H CD1 1 
ATOM 1245 C CD2 . PHE B 2 63  ? 137.644 113.354 109.026 1.00 50.20  ? 79  PHE H CD2 1 
ATOM 1246 C CE1 . PHE B 2 63  ? 137.138 112.708 111.650 1.00 50.20  ? 79  PHE H CE1 1 
ATOM 1247 C CE2 . PHE B 2 63  ? 137.104 112.127 109.336 1.00 50.20  ? 79  PHE H CE2 1 
ATOM 1248 C CZ  . PHE B 2 63  ? 136.852 111.803 110.649 1.00 50.20  ? 79  PHE H CZ  1 
ATOM 1249 N N   . ASN B 2 64  ? 138.732 118.142 111.570 1.00 54.97  ? 80  ASN H N   1 
ATOM 1250 C CA  . ASN B 2 64  ? 139.768 119.060 112.004 1.00 54.97  ? 80  ASN H CA  1 
ATOM 1251 C C   . ASN B 2 64  ? 141.131 118.428 111.759 1.00 54.97  ? 80  ASN H C   1 
ATOM 1252 O O   . ASN B 2 64  ? 141.280 117.203 111.764 1.00 54.97  ? 80  ASN H O   1 
ATOM 1253 C CB  . ASN B 2 64  ? 139.598 119.406 113.483 1.00 54.97  ? 80  ASN H CB  1 
ATOM 1254 C CG  . ASN B 2 64  ? 140.354 120.655 113.880 1.00 54.97  ? 80  ASN H CG  1 
ATOM 1255 O OD1 . ASN B 2 64  ? 141.502 120.852 113.487 1.00 54.97  ? 80  ASN H OD1 1 
ATOM 1256 N ND2 . ASN B 2 64  ? 139.711 121.509 114.665 1.00 54.97  ? 80  ASN H ND2 1 
ATOM 1257 N N   . GLU B 2 65  ? 142.132 119.277 111.527 1.00 59.44  ? 81  GLU H N   1 
ATOM 1258 C CA  . GLU B 2 65  ? 143.464 118.772 111.211 1.00 59.44  ? 81  GLU H CA  1 
ATOM 1259 C C   . GLU B 2 65  ? 144.069 118.018 112.389 1.00 59.44  ? 81  GLU H C   1 
ATOM 1260 O O   . GLU B 2 65  ? 144.739 116.996 112.204 1.00 59.44  ? 81  GLU H O   1 
ATOM 1261 C CB  . GLU B 2 65  ? 144.372 119.924 110.784 1.00 59.44  ? 81  GLU H CB  1 
ATOM 1262 C CG  . GLU B 2 65  ? 144.161 120.393 109.349 1.00 59.44  ? 81  GLU H CG  1 
ATOM 1263 C CD  . GLU B 2 65  ? 144.530 119.347 108.308 1.00 59.44  ? 81  GLU H CD  1 
ATOM 1264 O OE1 . GLU B 2 65  ? 145.148 118.321 108.666 1.00 59.44  ? 81  GLU H OE1 1 
ATOM 1265 O OE2 . GLU B 2 65  ? 144.199 119.553 107.121 1.00 59.44  ? 81  GLU H OE2 1 
ATOM 1266 N N   . LYS B 2 66  ? 143.847 118.510 113.609 1.00 59.56  ? 82  LYS H N   1 
ATOM 1267 C CA  . LYS B 2 66  ? 144.454 117.889 114.783 1.00 59.56  ? 82  LYS H CA  1 
ATOM 1268 C C   . LYS B 2 66  ? 143.897 116.494 115.030 1.00 59.56  ? 82  LYS H C   1 
ATOM 1269 O O   . LYS B 2 66  ? 144.632 115.587 115.436 1.00 59.56  ? 82  LYS H O   1 
ATOM 1270 C CB  . LYS B 2 66  ? 144.237 118.771 116.011 1.00 59.56  ? 82  LYS H CB  1 
ATOM 1271 C CG  . LYS B 2 66  ? 144.414 120.252 115.748 1.00 59.56  ? 82  LYS H CG  1 
ATOM 1272 C CD  . LYS B 2 66  ? 144.540 121.025 117.047 1.00 59.56  ? 82  LYS H CD  1 
ATOM 1273 C CE  . LYS B 2 66  ? 143.193 121.181 117.729 1.00 59.56  ? 82  LYS H CE  1 
ATOM 1274 N NZ  . LYS B 2 66  ? 143.023 122.537 118.320 1.00 59.56  ? 82  LYS H NZ  1 
ATOM 1275 N N   . PHE B 2 67  ? 142.602 116.301 114.795 1.00 58.19  ? 83  PHE H N   1 
ATOM 1276 C CA  . PHE B 2 67  ? 141.919 115.063 115.142 1.00 58.19  ? 83  PHE H CA  1 
ATOM 1277 C C   . PHE B 2 67  ? 141.774 114.110 113.965 1.00 58.19  ? 83  PHE H C   1 
ATOM 1278 O O   . PHE B 2 67  ? 141.044 113.121 114.071 1.00 58.19  ? 83  PHE H O   1 
ATOM 1279 C CB  . PHE B 2 67  ? 140.546 115.378 115.731 1.00 58.19  ? 83  PHE H CB  1 
ATOM 1280 C CG  . PHE B 2 67  ? 140.607 116.134 117.021 1.00 58.19  ? 83  PHE H CG  1 
ATOM 1281 C CD1 . PHE B 2 67  ? 140.024 117.381 117.136 1.00 58.19  ? 83  PHE H CD1 1 
ATOM 1282 C CD2 . PHE B 2 67  ? 141.251 115.600 118.120 1.00 58.19  ? 83  PHE H CD2 1 
ATOM 1283 C CE1 . PHE B 2 67  ? 140.080 118.080 118.319 1.00 58.19  ? 83  PHE H CE1 1 
ATOM 1284 C CE2 . PHE B 2 67  ? 141.310 116.295 119.309 1.00 58.19  ? 83  PHE H CE2 1 
ATOM 1285 C CZ  . PHE B 2 67  ? 140.723 117.538 119.408 1.00 58.19  ? 83  PHE H CZ  1 
ATOM 1286 N N   . LYS B 2 68  ? 142.450 114.382 112.847 1.00 60.15  ? 84  LYS H N   1 
ATOM 1287 C CA  . LYS B 2 68  ? 142.310 113.525 111.675 1.00 60.15  ? 84  LYS H CA  1 
ATOM 1288 C C   . LYS B 2 68  ? 142.839 112.122 111.935 1.00 60.15  ? 84  LYS H C   1 
ATOM 1289 O O   . LYS B 2 68  ? 142.259 111.142 111.454 1.00 60.15  ? 84  LYS H O   1 
ATOM 1290 C CB  . LYS B 2 68  ? 143.028 114.149 110.479 1.00 60.15  ? 84  LYS H CB  1 
ATOM 1291 C CG  . LYS B 2 68  ? 142.826 113.396 109.176 1.00 60.15  ? 84  LYS H CG  1 
ATOM 1292 C CD  . LYS B 2 68  ? 143.202 114.250 107.976 1.00 60.15  ? 84  LYS H CD  1 
ATOM 1293 C CE  . LYS B 2 68  ? 142.555 115.624 108.043 1.00 60.15  ? 84  LYS H CE  1 
ATOM 1294 N NZ  . LYS B 2 68  ? 141.201 115.633 107.423 1.00 60.15  ? 84  LYS H NZ  1 
ATOM 1295 N N   . THR B 2 69  ? 143.929 112.001 112.690 1.00 63.31  ? 85  THR H N   1 
ATOM 1296 C CA  . THR B 2 69  ? 144.562 110.715 112.956 1.00 63.31  ? 85  THR H CA  1 
ATOM 1297 C C   . THR B 2 69  ? 144.153 110.132 114.304 1.00 63.31  ? 85  THR H C   1 
ATOM 1298 O O   . THR B 2 69  ? 144.748 109.149 114.756 1.00 63.31  ? 85  THR H O   1 
ATOM 1299 C CB  . THR B 2 69  ? 146.082 110.849 112.880 1.00 63.31  ? 85  THR H CB  1 
ATOM 1300 O OG1 . THR B 2 69  ? 146.685 109.556 113.014 1.00 63.31  ? 85  THR H OG1 1 
ATOM 1301 C CG2 . THR B 2 69  ? 146.592 111.758 113.987 1.00 63.31  ? 85  THR H CG2 1 
ATOM 1302 N N   . LYS B 2 70  ? 143.147 110.713 114.954 1.00 64.10  ? 86  LYS H N   1 
ATOM 1303 C CA  . LYS B 2 70  ? 142.740 110.284 116.285 1.00 64.10  ? 86  LYS H CA  1 
ATOM 1304 C C   . LYS B 2 70  ? 141.279 109.879 116.391 1.00 64.10  ? 86  LYS H C   1 
ATOM 1305 O O   . LYS B 2 70  ? 140.966 109.005 117.208 1.00 64.10  ? 86  LYS H O   1 
ATOM 1306 C CB  . LYS B 2 70  ? 143.017 111.397 117.308 1.00 64.10  ? 86  LYS H CB  1 
ATOM 1307 C CG  . LYS B 2 70  ? 142.771 111.010 118.754 1.00 64.10  ? 86  LYS H CG  1 
ATOM 1308 C CD  . LYS B 2 70  ? 143.222 112.113 119.692 1.00 64.10  ? 86  LYS H CD  1 
ATOM 1309 C CE  . LYS B 2 70  ? 143.495 111.578 121.085 1.00 64.10  ? 86  LYS H CE  1 
ATOM 1310 N NZ  . LYS B 2 70  ? 144.250 110.298 121.039 1.00 64.10  ? 86  LYS H NZ  1 
ATOM 1311 N N   . ALA B 2 71  ? 140.381 110.460 115.600 1.00 60.10  ? 87  ALA H N   1 
ATOM 1312 C CA  . ALA B 2 71  ? 138.963 110.160 115.717 1.00 60.10  ? 87  ALA H CA  1 
ATOM 1313 C C   . ALA B 2 71  ? 138.363 109.948 114.338 1.00 60.10  ? 87  ALA H C   1 
ATOM 1314 O O   . ALA B 2 71  ? 138.719 110.643 113.384 1.00 60.10  ? 87  ALA H O   1 
ATOM 1315 C CB  . ALA B 2 71  ? 138.215 111.283 116.441 1.00 60.10  ? 87  ALA H CB  1 
ATOM 1316 N N   . THR B 2 72  ? 137.458 108.978 114.243 1.00 58.05  ? 88  THR H N   1 
ATOM 1317 C CA  . THR B 2 72  ? 136.633 108.779 113.063 1.00 58.05  ? 88  THR H CA  1 
ATOM 1318 C C   . THR B 2 72  ? 135.187 108.619 113.504 1.00 58.05  ? 88  THR H C   1 
ATOM 1319 O O   . THR B 2 72  ? 134.905 108.066 114.570 1.00 58.05  ? 88  THR H O   1 
ATOM 1320 C CB  . THR B 2 72  ? 137.077 107.558 112.242 1.00 58.05  ? 88  THR H CB  1 
ATOM 1321 O OG1 . THR B 2 72  ? 136.251 107.438 111.078 1.00 58.05  ? 88  THR H OG1 1 
ATOM 1322 C CG2 . THR B 2 72  ? 136.977 106.285 113.061 1.00 58.05  ? 88  THR H CG2 1 
ATOM 1323 N N   . LEU B 2 73  ? 134.269 109.121 112.684 1.00 52.87  ? 89  LEU H N   1 
ATOM 1324 C CA  . LEU B 2 73  ? 132.861 109.150 113.044 1.00 52.87  ? 89  LEU H CA  1 
ATOM 1325 C C   . LEU B 2 73  ? 132.013 108.619 111.899 1.00 52.87  ? 89  LEU H C   1 
ATOM 1326 O O   . LEU B 2 73  ? 132.348 108.800 110.726 1.00 52.87  ? 89  LEU H O   1 
ATOM 1327 C CB  . LEU B 2 73  ? 132.414 110.566 113.434 1.00 52.87  ? 89  LEU H CB  1 
ATOM 1328 C CG  . LEU B 2 73  ? 132.252 111.646 112.369 1.00 52.87  ? 89  LEU H CG  1 
ATOM 1329 C CD1 . LEU B 2 73  ? 131.459 112.802 112.940 1.00 52.87  ? 89  LEU H CD1 1 
ATOM 1330 C CD2 . LEU B 2 73  ? 133.596 112.136 111.883 1.00 52.87  ? 89  LEU H CD2 1 
ATOM 1331 N N   . THR B 2 74  ? 130.913 107.960 112.259 1.00 54.53  ? 90  THR H N   1 
ATOM 1332 C CA  . THR B 2 74  ? 130.045 107.284 111.305 1.00 54.53  ? 90  THR H CA  1 
ATOM 1333 C C   . THR B 2 74  ? 128.595 107.425 111.745 1.00 54.53  ? 90  THR H C   1 
ATOM 1334 O O   . THR B 2 74  ? 128.296 107.938 112.825 1.00 54.53  ? 90  THR H O   1 
ATOM 1335 C CB  . THR B 2 74  ? 130.404 105.801 111.166 1.00 54.53  ? 90  THR H CB  1 
ATOM 1336 O OG1 . THR B 2 74  ? 130.560 105.223 112.467 1.00 54.53  ? 90  THR H OG1 1 
ATOM 1337 C CG2 . THR B 2 74  ? 131.690 105.625 110.375 1.00 54.53  ? 90  THR H CG2 1 
ATOM 1338 N N   . VAL B 2 75  ? 127.690 106.952 110.893 1.00 53.97  ? 91  VAL H N   1 
ATOM 1339 C CA  . VAL B 2 75  ? 126.261 106.988 111.168 1.00 53.97  ? 91  VAL H CA  1 
ATOM 1340 C C   . VAL B 2 75  ? 125.693 105.578 111.116 1.00 53.97  ? 91  VAL H C   1 
ATOM 1341 O O   . VAL B 2 75  ? 126.281 104.651 110.551 1.00 53.97  ? 91  VAL H O   1 
ATOM 1342 C CB  . VAL B 2 75  ? 125.496 107.904 110.191 1.00 53.97  ? 91  VAL H CB  1 
ATOM 1343 C CG1 . VAL B 2 75  ? 125.830 109.353 110.446 1.00 53.97  ? 91  VAL H CG1 1 
ATOM 1344 C CG2 . VAL B 2 75  ? 125.819 107.528 108.758 1.00 53.97  ? 91  VAL H CG2 1 
ATOM 1345 N N   . ASP B 2 76  ? 124.519 105.426 111.723 1.00 57.04  ? 92  ASP H N   1 
ATOM 1346 C CA  . ASP B 2 76  ? 123.721 104.205 111.662 1.00 57.04  ? 92  ASP H CA  1 
ATOM 1347 C C   . ASP B 2 76  ? 122.299 104.652 111.341 1.00 57.04  ? 92  ASP H C   1 
ATOM 1348 O O   . ASP B 2 76  ? 121.592 105.169 112.214 1.00 57.04  ? 92  ASP H O   1 
ATOM 1349 C CB  . ASP B 2 76  ? 123.791 103.424 112.970 1.00 57.04  ? 92  ASP H CB  1 
ATOM 1350 C CG  . ASP B 2 76  ? 123.039 102.109 112.909 1.00 57.04  ? 92  ASP H CG  1 
ATOM 1351 O OD1 . ASP B 2 76  ? 121.790 102.132 112.910 1.00 57.04  ? 92  ASP H OD1 1 
ATOM 1352 O OD2 . ASP B 2 76  ? 123.697 101.049 112.861 1.00 57.04  ? 92  ASP H OD2 1 
ATOM 1353 N N   . ARG B 2 77  ? 121.895 104.466 110.082 1.00 53.79  ? 93  ARG H N   1 
ATOM 1354 C CA  . ARG B 2 77  ? 120.610 104.981 109.624 1.00 53.79  ? 93  ARG H CA  1 
ATOM 1355 C C   . ARG B 2 77  ? 119.441 104.173 110.169 1.00 53.79  ? 93  ARG H C   1 
ATOM 1356 O O   . ARG B 2 77  ? 118.360 104.728 110.392 1.00 53.79  ? 93  ARG H O   1 
ATOM 1357 C CB  . ARG B 2 77  ? 120.569 104.996 108.097 1.00 53.79  ? 93  ARG H CB  1 
ATOM 1358 C CG  . ARG B 2 77  ? 120.931 106.332 107.479 1.00 53.79  ? 93  ARG H CG  1 
ATOM 1359 C CD  . ARG B 2 77  ? 121.555 106.141 106.110 1.00 53.79  ? 93  ARG H CD  1 
ATOM 1360 N NE  . ARG B 2 77  ? 123.002 105.994 106.191 1.00 53.79  ? 93  ARG H NE  1 
ATOM 1361 C CZ  . ARG B 2 77  ? 123.815 106.001 105.145 1.00 53.79  ? 93  ARG H CZ  1 
ATOM 1362 N NH1 . ARG B 2 77  ? 123.354 106.138 103.913 1.00 53.79  ? 93  ARG H NH1 1 
ATOM 1363 N NH2 . ARG B 2 77  ? 125.123 105.864 105.339 1.00 53.79  ? 93  ARG H NH2 1 
ATOM 1364 N N   . SER B 2 78  ? 119.628 102.867 110.371 1.00 56.50  ? 94  SER H N   1 
ATOM 1365 C CA  . SER B 2 78  ? 118.532 102.026 110.841 1.00 56.50  ? 94  SER H CA  1 
ATOM 1366 C C   . SER B 2 78  ? 118.059 102.456 112.224 1.00 56.50  ? 94  SER H C   1 
ATOM 1367 O O   . SER B 2 78  ? 116.853 102.587 112.466 1.00 56.50  ? 94  SER H O   1 
ATOM 1368 C CB  . SER B 2 78  ? 118.965 100.561 110.851 1.00 56.50  ? 94  SER H CB  1 
ATOM 1369 O OG  . SER B 2 78  ? 120.029 100.354 111.763 1.00 56.50  ? 94  SER H OG  1 
ATOM 1370 N N   . SER B 2 79  ? 118.993 102.685 113.143 1.00 58.24  ? 95  SER H N   1 
ATOM 1371 C CA  . SER B 2 79  ? 118.665 103.142 114.485 1.00 58.24  ? 95  SER H CA  1 
ATOM 1372 C C   . SER B 2 79  ? 118.747 104.655 114.631 1.00 58.24  ? 95  SER H C   1 
ATOM 1373 O O   . SER B 2 79  ? 118.427 105.175 115.704 1.00 58.24  ? 95  SER H O   1 
ATOM 1374 C CB  . SER B 2 79  ? 119.587 102.476 115.511 1.00 58.24  ? 95  SER H CB  1 
ATOM 1375 O OG  . SER B 2 79  ? 120.928 102.900 115.342 1.00 58.24  ? 95  SER H OG  1 
ATOM 1376 N N   . SER B 2 80  ? 119.165 105.366 113.583 1.00 57.58  ? 96  SER H N   1 
ATOM 1377 C CA  . SER B 2 80  ? 119.293 106.822 113.602 1.00 57.58  ? 96  SER H CA  1 
ATOM 1378 C C   . SER B 2 80  ? 120.226 107.274 114.727 1.00 57.58  ? 96  SER H C   1 
ATOM 1379 O O   . SER B 2 80  ? 119.824 107.957 115.670 1.00 57.58  ? 96  SER H O   1 
ATOM 1380 C CB  . SER B 2 80  ? 117.922 107.493 113.722 1.00 57.58  ? 96  SER H CB  1 
ATOM 1381 O OG  . SER B 2 80  ? 117.437 107.415 115.048 1.00 57.58  ? 96  SER H OG  1 
ATOM 1382 N N   . THR B 2 81  ? 121.489 106.872 114.614 1.00 57.94  ? 97  THR H N   1 
ATOM 1383 C CA  . THR B 2 81  ? 122.472 107.161 115.648 1.00 57.94  ? 97  THR H CA  1 
ATOM 1384 C C   . THR B 2 81  ? 123.762 107.633 114.991 1.00 57.94  ? 97  THR H C   1 
ATOM 1385 O O   . THR B 2 81  ? 124.046 107.308 113.838 1.00 57.94  ? 97  THR H O   1 
ATOM 1386 C CB  . THR B 2 81  ? 122.726 105.923 116.523 1.00 57.94  ? 97  THR H CB  1 
ATOM 1387 O OG1 . THR B 2 81  ? 121.471 105.373 116.942 1.00 57.94  ? 97  THR H OG1 1 
ATOM 1388 C CG2 . THR B 2 81  ? 123.521 106.287 117.765 1.00 57.94  ? 97  THR H CG2 1 
ATOM 1389 N N   . ALA B 2 82  ? 124.541 108.420 115.730 1.00 55.36  ? 98  ALA H N   1 
ATOM 1390 C CA  . ALA B 2 82  ? 125.854 108.868 115.285 1.00 55.36  ? 98  ALA H CA  1 
ATOM 1391 C C   . ALA B 2 82  ? 126.910 108.344 116.244 1.00 55.36  ? 98  ALA H C   1 
ATOM 1392 O O   . ALA B 2 82  ? 126.764 108.476 117.463 1.00 55.36  ? 98  ALA H O   1 
ATOM 1393 C CB  . ALA B 2 82  ? 125.920 110.394 115.207 1.00 55.36  ? 98  ALA H CB  1 
ATOM 1394 N N   . TYR B 2 83  ? 127.970 107.753 115.700 1.00 57.28  ? 99  TYR H N   1 
ATOM 1395 C CA  . TYR B 2 83  ? 129.038 107.173 116.498 1.00 57.28  ? 99  TYR H CA  1 
ATOM 1396 C C   . TYR B 2 83  ? 130.351 107.898 116.240 1.00 57.28  ? 99  TYR H C   1 
ATOM 1397 O O   . TYR B 2 83  ? 130.619 108.354 115.126 1.00 57.28  ? 99  TYR H O   1 
ATOM 1398 C CB  . TYR B 2 83  ? 129.212 105.685 116.190 1.00 57.28  ? 99  TYR H CB  1 
ATOM 1399 C CG  . TYR B 2 83  ? 127.975 104.855 116.418 1.00 57.28  ? 99  TYR H CG  1 
ATOM 1400 C CD1 . TYR B 2 83  ? 127.374 104.802 117.665 1.00 57.28  ? 99  TYR H CD1 1 
ATOM 1401 C CD2 . TYR B 2 83  ? 127.409 104.122 115.387 1.00 57.28  ? 99  TYR H CD2 1 
ATOM 1402 C CE1 . TYR B 2 83  ? 126.246 104.042 117.880 1.00 57.28  ? 99  TYR H CE1 1 
ATOM 1403 C CE2 . TYR B 2 83  ? 126.280 103.360 115.592 1.00 57.28  ? 99  TYR H CE2 1 
ATOM 1404 C CZ  . TYR B 2 83  ? 125.702 103.325 116.840 1.00 57.28  ? 99  TYR H CZ  1 
ATOM 1405 O OH  . TYR B 2 83  ? 124.575 102.567 117.050 1.00 57.28  ? 99  TYR H OH  1 
ATOM 1406 N N   . MET B 2 84  ? 131.173 107.985 117.284 1.00 58.33  ? 100 MET H N   1 
ATOM 1407 C CA  . MET B 2 84  ? 132.478 108.629 117.197 1.00 58.33  ? 100 MET H CA  1 
ATOM 1408 C C   . MET B 2 84  ? 133.490 107.752 117.922 1.00 58.33  ? 100 MET H C   1 
ATOM 1409 O O   . MET B 2 84  ? 133.176 107.197 118.976 1.00 58.33  ? 100 MET H O   1 
ATOM 1410 C CB  . MET B 2 84  ? 132.435 110.031 117.806 1.00 58.33  ? 100 MET H CB  1 
ATOM 1411 C CG  . MET B 2 84  ? 133.523 110.956 117.316 1.00 58.33  ? 100 MET H CG  1 
ATOM 1412 S SD  . MET B 2 84  ? 134.940 110.959 118.415 1.00 58.33  ? 100 MET H SD  1 
ATOM 1413 C CE  . MET B 2 84  ? 134.509 112.313 119.497 1.00 58.33  ? 100 MET H CE  1 
ATOM 1414 N N   . GLN B 2 85  ? 134.697 107.629 117.366 1.00 63.76  ? 101 GLN H N   1 
ATOM 1415 C CA  . GLN B 2 85  ? 135.590 106.557 117.801 1.00 63.76  ? 101 GLN H CA  1 
ATOM 1416 C C   . GLN B 2 85  ? 136.544 106.981 118.916 1.00 63.76  ? 101 GLN H C   1 
ATOM 1417 O O   . GLN B 2 85  ? 136.533 106.391 120.000 1.00 63.76  ? 101 GLN H O   1 
ATOM 1418 C CB  . GLN B 2 85  ? 136.379 106.015 116.609 1.00 63.76  ? 101 GLN H CB  1 
ATOM 1419 C CG  . GLN B 2 85  ? 136.792 104.559 116.761 1.00 63.76  ? 101 GLN H CG  1 
ATOM 1420 C CD  . GLN B 2 85  ? 135.669 103.677 117.273 1.00 63.76  ? 101 GLN H CD  1 
ATOM 1421 O OE1 . GLN B 2 85  ? 134.531 103.763 116.811 1.00 63.76  ? 101 GLN H OE1 1 
ATOM 1422 N NE2 . GLN B 2 85  ? 135.986 102.823 118.238 1.00 63.76  ? 101 GLN H NE2 1 
ATOM 1423 N N   . LEU B 2 86  ? 137.390 107.983 118.667 1.00 63.87  ? 102 LEU H N   1 
ATOM 1424 C CA  . LEU B 2 86  ? 138.525 108.292 119.544 1.00 63.87  ? 102 LEU H CA  1 
ATOM 1425 C C   . LEU B 2 86  ? 139.441 107.071 119.679 1.00 63.87  ? 102 LEU H C   1 
ATOM 1426 O O   . LEU B 2 86  ? 139.589 106.470 120.744 1.00 63.87  ? 102 LEU H O   1 
ATOM 1427 C CB  . LEU B 2 86  ? 138.059 108.790 120.918 1.00 63.87  ? 102 LEU H CB  1 
ATOM 1428 C CG  . LEU B 2 86  ? 137.348 110.138 120.988 1.00 63.87  ? 102 LEU H CG  1 
ATOM 1429 C CD1 . LEU B 2 86  ? 137.340 110.638 122.414 1.00 63.87  ? 102 LEU H CD1 1 
ATOM 1430 C CD2 . LEU B 2 86  ? 138.043 111.142 120.091 1.00 63.87  ? 102 LEU H CD2 1 
ATOM 1431 N N   . SER B 2 87  ? 140.054 106.725 118.543 1.00 68.88  ? 103 SER H N   1 
ATOM 1432 C CA  . SER B 2 87  ? 140.744 105.444 118.400 1.00 68.88  ? 103 SER H CA  1 
ATOM 1433 C C   . SER B 2 87  ? 141.855 105.250 119.426 1.00 68.88  ? 103 SER H C   1 
ATOM 1434 O O   . SER B 2 87  ? 142.190 104.108 119.759 1.00 68.88  ? 103 SER H O   1 
ATOM 1435 C CB  . SER B 2 87  ? 141.317 105.316 116.987 1.00 68.88  ? 103 SER H CB  1 
ATOM 1436 O OG  . SER B 2 87  ? 140.286 105.273 116.015 1.00 68.88  ? 103 SER H OG  1 
ATOM 1437 N N   . SER B 2 88  ? 142.456 106.328 119.919 1.00 69.59  ? 104 SER H N   1 
ATOM 1438 C CA  . SER B 2 88  ? 143.525 106.221 120.909 1.00 69.59  ? 104 SER H CA  1 
ATOM 1439 C C   . SER B 2 88  ? 143.307 107.292 121.966 1.00 69.59  ? 104 SER H C   1 
ATOM 1440 O O   . SER B 2 88  ? 143.028 108.447 121.631 1.00 69.59  ? 104 SER H O   1 
ATOM 1441 C CB  . SER B 2 88  ? 144.901 106.364 120.261 1.00 69.59  ? 104 SER H CB  1 
ATOM 1442 O OG  . SER B 2 88  ? 145.157 105.289 119.374 1.00 69.59  ? 104 SER H OG  1 
ATOM 1443 N N   . LEU B 2 89  ? 143.432 106.914 123.234 1.00 70.50  ? 105 LEU H N   1 
ATOM 1444 C CA  . LEU B 2 89  ? 143.193 107.822 124.346 1.00 70.50  ? 105 LEU H CA  1 
ATOM 1445 C C   . LEU B 2 89  ? 144.425 107.904 125.236 1.00 70.50  ? 105 LEU H C   1 
ATOM 1446 O O   . LEU B 2 89  ? 144.981 106.876 125.635 1.00 70.50  ? 105 LEU H O   1 
ATOM 1447 C CB  . LEU B 2 89  ? 141.981 107.372 125.161 1.00 70.50  ? 105 LEU H CB  1 
ATOM 1448 C CG  . LEU B 2 89  ? 140.646 107.441 124.425 1.00 70.50  ? 105 LEU H CG  1 
ATOM 1449 C CD1 . LEU B 2 89  ? 139.496 107.188 125.377 1.00 70.50  ? 105 LEU H CD1 1 
ATOM 1450 C CD2 . LEU B 2 89  ? 140.492 108.794 123.757 1.00 70.50  ? 105 LEU H CD2 1 
ATOM 1451 N N   . THR B 2 90  ? 144.842 109.126 125.544 1.00 73.26  ? 106 THR H N   1 
ATOM 1452 C CA  . THR B 2 90  ? 145.929 109.407 126.464 1.00 73.26  ? 106 THR H CA  1 
ATOM 1453 C C   . THR B 2 90  ? 145.375 110.147 127.681 1.00 73.26  ? 106 THR H C   1 
ATOM 1454 O O   . THR B 2 90  ? 144.160 110.314 127.833 1.00 73.26  ? 106 THR H O   1 
ATOM 1455 C CB  . THR B 2 90  ? 147.028 110.205 125.761 1.00 73.26  ? 106 THR H CB  1 
ATOM 1456 O OG1 . THR B 2 90  ? 146.503 111.464 125.326 1.00 73.26  ? 106 THR H OG1 1 
ATOM 1457 C CG2 . THR B 2 90  ? 147.551 109.441 124.558 1.00 73.26  ? 106 THR H CG2 1 
ATOM 1458 N N   . PHE B 2 91  ? 146.276 110.587 128.560 1.00 75.23  ? 107 PHE H N   1 
ATOM 1459 C CA  . PHE B 2 91  ? 145.854 111.254 129.786 1.00 75.23  ? 107 PHE H CA  1 
ATOM 1460 C C   . PHE B 2 91  ? 145.171 112.591 129.525 1.00 75.23  ? 107 PHE H C   1 
ATOM 1461 O O   . PHE B 2 91  ? 144.240 112.945 130.256 1.00 75.23  ? 107 PHE H O   1 
ATOM 1462 C CB  . PHE B 2 91  ? 147.051 111.456 130.714 1.00 75.23  ? 107 PHE H CB  1 
ATOM 1463 C CG  . PHE B 2 91  ? 147.190 110.391 131.761 1.00 75.23  ? 107 PHE H CG  1 
ATOM 1464 C CD1 . PHE B 2 91  ? 148.333 109.614 131.829 1.00 75.23  ? 107 PHE H CD1 1 
ATOM 1465 C CD2 . PHE B 2 91  ? 146.176 110.165 132.675 1.00 75.23  ? 107 PHE H CD2 1 
ATOM 1466 C CE1 . PHE B 2 91  ? 148.463 108.632 132.791 1.00 75.23  ? 107 PHE H CE1 1 
ATOM 1467 C CE2 . PHE B 2 91  ? 146.300 109.185 133.640 1.00 75.23  ? 107 PHE H CE2 1 
ATOM 1468 C CZ  . PHE B 2 91  ? 147.445 108.417 133.698 1.00 75.23  ? 107 PHE H CZ  1 
ATOM 1469 N N   . GLU B 2 92  ? 145.607 113.340 128.516 1.00 76.28  ? 108 GLU H N   1 
ATOM 1470 C CA  . GLU B 2 92  ? 145.058 114.661 128.221 1.00 76.28  ? 108 GLU H CA  1 
ATOM 1471 C C   . GLU B 2 92  ? 143.939 114.510 127.193 1.00 76.28  ? 108 GLU H C   1 
ATOM 1472 O O   . GLU B 2 92  ? 143.963 115.112 126.119 1.00 76.28  ? 108 GLU H O   1 
ATOM 1473 C CB  . GLU B 2 92  ? 146.158 115.613 127.727 1.00 76.28  ? 108 GLU H CB  1 
ATOM 1474 C CG  . GLU B 2 92  ? 147.176 116.004 128.791 1.00 76.28  ? 108 GLU H CG  1 
ATOM 1475 C CD  . GLU B 2 92  ? 148.311 115.007 128.924 1.00 76.28  ? 108 GLU H CD  1 
ATOM 1476 O OE1 . GLU B 2 92  ? 148.050 113.789 128.860 1.00 76.28  ? 108 GLU H OE1 1 
ATOM 1477 O OE2 . GLU B 2 92  ? 149.468 115.444 129.100 1.00 76.28  ? 108 GLU H OE2 1 
ATOM 1478 N N   . ASP B 2 93  ? 142.936 113.706 127.546 1.00 72.71  ? 109 ASP H N   1 
ATOM 1479 C CA  . ASP B 2 93  ? 141.742 113.544 126.724 1.00 72.71  ? 109 ASP H CA  1 
ATOM 1480 C C   . ASP B 2 93  ? 140.444 113.633 127.507 1.00 72.71  ? 109 ASP H C   1 
ATOM 1481 O O   . ASP B 2 93  ? 139.380 113.650 126.882 1.00 72.71  ? 109 ASP H O   1 
ATOM 1482 C CB  . ASP B 2 93  ? 141.771 112.205 125.977 1.00 72.71  ? 109 ASP H CB  1 
ATOM 1483 C CG  . ASP B 2 93  ? 142.955 112.084 125.047 1.00 72.71  ? 109 ASP H CG  1 
ATOM 1484 O OD1 . ASP B 2 93  ? 143.279 113.076 124.364 1.00 72.71  ? 109 ASP H OD1 1 
ATOM 1485 O OD2 . ASP B 2 93  ? 143.560 110.996 124.994 1.00 72.71  ? 109 ASP H OD2 1 
ATOM 1486 N N   . SER B 2 94  ? 140.483 113.673 128.837 1.00 69.77  ? 110 SER H N   1 
ATOM 1487 C CA  . SER B 2 94  ? 139.268 113.777 129.632 1.00 69.77  ? 110 SER H CA  1 
ATOM 1488 C C   . SER B 2 94  ? 138.596 115.121 129.392 1.00 69.77  ? 110 SER H C   1 
ATOM 1489 O O   . SER B 2 94  ? 139.109 116.163 129.811 1.00 69.77  ? 110 SER H O   1 
ATOM 1490 C CB  . SER B 2 94  ? 139.579 113.592 131.117 1.00 69.77  ? 110 SER H CB  1 
ATOM 1491 O OG  . SER B 2 94  ? 138.402 113.696 131.898 1.00 69.77  ? 110 SER H OG  1 
ATOM 1492 N N   . ALA B 2 95  ? 137.453 115.106 128.717 1.00 63.09  ? 111 ALA H N   1 
ATOM 1493 C CA  . ALA B 2 95  ? 136.743 116.327 128.374 1.00 63.09  ? 111 ALA H CA  1 
ATOM 1494 C C   . ALA B 2 95  ? 135.261 115.999 128.242 1.00 63.09  ? 111 ALA H C   1 
ATOM 1495 O O   . ALA B 2 95  ? 134.818 114.901 128.586 1.00 63.09  ? 111 ALA H O   1 
ATOM 1496 C CB  . ALA B 2 95  ? 137.324 116.943 127.097 1.00 63.09  ? 111 ALA H CB  1 
ATOM 1497 N N   . VAL B 2 96  ? 134.492 116.960 127.740 1.00 60.57  ? 112 VAL H N   1 
ATOM 1498 C CA  . VAL B 2 96  ? 133.057 116.807 127.534 1.00 60.57  ? 112 VAL H CA  1 
ATOM 1499 C C   . VAL B 2 96  ? 132.790 116.851 126.037 1.00 60.57  ? 112 VAL H C   1 
ATOM 1500 O O   . VAL B 2 96  ? 133.246 117.770 125.348 1.00 60.57  ? 112 VAL H O   1 
ATOM 1501 C CB  . VAL B 2 96  ? 132.261 117.900 128.267 1.00 60.57  ? 112 VAL H CB  1 
ATOM 1502 C CG1 . VAL B 2 96  ? 130.776 117.667 128.102 1.00 60.57  ? 112 VAL H CG1 1 
ATOM 1503 C CG2 . VAL B 2 96  ? 132.640 117.935 129.734 1.00 60.57  ? 112 VAL H CG2 1 
ATOM 1504 N N   . TYR B 2 97  ? 132.060 115.861 125.535 1.00 56.27  ? 113 TYR H N   1 
ATOM 1505 C CA  . TYR B 2 97  ? 131.846 115.696 124.102 1.00 56.27  ? 113 TYR H CA  1 
ATOM 1506 C C   . TYR B 2 97  ? 130.372 115.920 123.786 1.00 56.27  ? 113 TYR H C   1 
ATOM 1507 O O   . TYR B 2 97  ? 129.520 115.113 124.171 1.00 56.27  ? 113 TYR H O   1 
ATOM 1508 C CB  . TYR B 2 97  ? 132.309 114.314 123.651 1.00 56.27  ? 113 TYR H CB  1 
ATOM 1509 C CG  . TYR B 2 97  ? 133.803 114.126 123.760 1.00 56.27  ? 113 TYR H CG  1 
ATOM 1510 C CD1 . TYR B 2 97  ? 134.382 113.686 124.940 1.00 56.27  ? 113 TYR H CD1 1 
ATOM 1511 C CD2 . TYR B 2 97  ? 134.635 114.403 122.690 1.00 56.27  ? 113 TYR H CD2 1 
ATOM 1512 C CE1 . TYR B 2 97  ? 135.746 113.519 125.044 1.00 56.27  ? 113 TYR H CE1 1 
ATOM 1513 C CE2 . TYR B 2 97  ? 135.998 114.240 122.788 1.00 56.27  ? 113 TYR H CE2 1 
ATOM 1514 C CZ  . TYR B 2 97  ? 136.548 113.799 123.964 1.00 56.27  ? 113 TYR H CZ  1 
ATOM 1515 O OH  . TYR B 2 97  ? 137.908 113.636 124.057 1.00 56.27  ? 113 TYR H OH  1 
ATOM 1516 N N   . TYR B 2 98  ? 130.077 117.009 123.085 1.00 55.27  ? 114 TYR H N   1 
ATOM 1517 C CA  . TYR B 2 98  ? 128.722 117.351 122.689 1.00 55.27  ? 114 TYR H CA  1 
ATOM 1518 C C   . TYR B 2 98  ? 128.478 116.960 121.239 1.00 55.27  ? 114 TYR H C   1 
ATOM 1519 O O   . TYR B 2 98  ? 129.359 117.088 120.384 1.00 55.27  ? 114 TYR H O   1 
ATOM 1520 C CB  . TYR B 2 98  ? 128.456 118.848 122.852 1.00 55.27  ? 114 TYR H CB  1 
ATOM 1521 C CG  . TYR B 2 98  ? 128.720 119.403 124.230 1.00 55.27  ? 114 TYR H CG  1 
ATOM 1522 C CD1 . TYR B 2 98  ? 127.847 119.156 125.278 1.00 55.27  ? 114 TYR H CD1 1 
ATOM 1523 C CD2 . TYR B 2 98  ? 129.835 120.190 124.478 1.00 55.27  ? 114 TYR H CD2 1 
ATOM 1524 C CE1 . TYR B 2 98  ? 128.083 119.668 126.534 1.00 55.27  ? 114 TYR H CE1 1 
ATOM 1525 C CE2 . TYR B 2 98  ? 130.078 120.705 125.730 1.00 55.27  ? 114 TYR H CE2 1 
ATOM 1526 C CZ  . TYR B 2 98  ? 129.200 120.442 126.754 1.00 55.27  ? 114 TYR H CZ  1 
ATOM 1527 O OH  . TYR B 2 98  ? 129.440 120.955 128.007 1.00 55.27  ? 114 TYR H OH  1 
ATOM 1528 N N   . CYS B 2 99  ? 127.266 116.484 120.971 1.00 54.62  ? 115 CYS H N   1 
ATOM 1529 C CA  . CYS B 2 99  ? 126.786 116.241 119.619 1.00 54.62  ? 115 CYS H CA  1 
ATOM 1530 C C   . CYS B 2 99  ? 125.635 117.194 119.344 1.00 54.62  ? 115 CYS H C   1 
ATOM 1531 O O   . CYS B 2 99  ? 124.665 117.235 120.106 1.00 54.62  ? 115 CYS H O   1 
ATOM 1532 C CB  . CYS B 2 99  ? 126.337 114.788 119.434 1.00 54.62  ? 115 CYS H CB  1 
ATOM 1533 S SG  . CYS B 2 99  ? 125.073 114.224 120.600 1.00 54.62  ? 115 CYS H SG  1 
ATOM 1534 N N   . ALA B 2 100 ? 125.747 117.966 118.268 1.00 46.76  ? 116 ALA H N   1 
ATOM 1535 C CA  . ALA B 2 100 ? 124.739 118.957 117.922 1.00 46.76  ? 116 ALA H CA  1 
ATOM 1536 C C   . ALA B 2 100 ? 124.409 118.860 116.443 1.00 46.76  ? 116 ALA H C   1 
ATOM 1537 O O   . ALA B 2 100 ? 125.307 118.720 115.614 1.00 46.76  ? 116 ALA H O   1 
ATOM 1538 C CB  . ALA B 2 100 ? 125.217 120.369 118.252 1.00 46.76  ? 116 ALA H CB  1 
ATOM 1539 N N   . ARG B 2 101 ? 123.129 118.944 116.104 1.00 47.03  ? 117 ARG H N   1 
ATOM 1540 C CA  . ARG B 2 101 ? 122.723 118.933 114.706 1.00 47.03  ? 117 ARG H CA  1 
ATOM 1541 C C   . ARG B 2 101 ? 122.642 120.366 114.208 1.00 47.03  ? 117 ARG H C   1 
ATOM 1542 O O   . ARG B 2 101 ? 122.121 121.243 114.903 1.00 47.03  ? 117 ARG H O   1 
ATOM 1543 C CB  . ARG B 2 101 ? 121.393 118.200 114.498 1.00 47.03  ? 117 ARG H CB  1 
ATOM 1544 C CG  . ARG B 2 101 ? 120.155 118.803 115.150 1.00 47.03  ? 117 ARG H CG  1 
ATOM 1545 C CD  . ARG B 2 101 ? 119.453 119.775 114.213 1.00 47.03  ? 117 ARG H CD  1 
ATOM 1546 N NE  . ARG B 2 101 ? 118.061 120.009 114.572 1.00 47.03  ? 117 ARG H NE  1 
ATOM 1547 C CZ  . ARG B 2 101 ? 117.254 120.834 113.920 1.00 47.03  ? 117 ARG H CZ  1 
ATOM 1548 N NH1 . ARG B 2 101 ? 117.695 121.590 112.929 1.00 47.03  ? 117 ARG H NH1 1 
ATOM 1549 N NH2 . ARG B 2 101 ? 115.977 120.913 114.279 1.00 47.03  ? 117 ARG H NH2 1 
ATOM 1550 N N   . GLY B 2 102 ? 123.192 120.607 113.025 1.00 44.02  ? 118 GLY H N   1 
ATOM 1551 C CA  . GLY B 2 102 ? 123.106 121.914 112.415 1.00 44.02  ? 118 GLY H CA  1 
ATOM 1552 C C   . GLY B 2 102 ? 123.302 121.854 110.919 1.00 44.02  ? 118 GLY H C   1 
ATOM 1553 O O   . GLY B 2 102 ? 124.294 121.299 110.438 1.00 44.02  ? 118 GLY H O   1 
ATOM 1554 N N   . GLY B 2 103 ? 122.361 122.416 110.170 1.00 45.80  ? 119 GLY H N   1 
ATOM 1555 C CA  . GLY B 2 103 ? 122.484 122.455 108.730 1.00 45.80  ? 119 GLY H CA  1 
ATOM 1556 C C   . GLY B 2 103 ? 121.399 121.698 108.000 1.00 45.80  ? 119 GLY H C   1 
ATOM 1557 O O   . GLY B 2 103 ? 120.309 121.482 108.534 1.00 45.80  ? 119 GLY H O   1 
ATOM 1558 N N   . ILE B 2 104 ? 121.696 121.292 106.767 1.00 42.50  ? 120 ILE H N   1 
ATOM 1559 C CA  . ILE B 2 104 ? 120.770 120.515 105.955 1.00 42.50  ? 120 ILE H CA  1 
ATOM 1560 C C   . ILE B 2 104 ? 121.601 119.810 104.897 1.00 42.50  ? 120 ILE H C   1 
ATOM 1561 O O   . ILE B 2 104 ? 122.737 120.196 104.621 1.00 42.50  ? 120 ILE H O   1 
ATOM 1562 C CB  . ILE B 2 104 ? 119.670 121.406 105.325 1.00 42.50  ? 120 ILE H CB  1 
ATOM 1563 C CG1 . ILE B 2 104 ? 118.392 120.606 105.099 1.00 42.50  ? 120 ILE H CG1 1 
ATOM 1564 C CG2 . ILE B 2 104 ? 120.137 121.966 104.016 1.00 42.50  ? 120 ILE H CG2 1 
ATOM 1565 C CD1 . ILE B 2 104 ? 117.185 121.468 104.840 1.00 42.50  ? 120 ILE H CD1 1 
ATOM 1566 N N   . HIS B 2 105 ? 121.040 118.762 104.305 1.00 42.04  ? 121 HIS H N   1 
ATOM 1567 C CA  . HIS B 2 105 ? 121.861 117.889 103.478 1.00 42.04  ? 121 HIS H CA  1 
ATOM 1568 C C   . HIS B 2 105 ? 122.190 118.469 102.106 1.00 42.04  ? 121 HIS H C   1 
ATOM 1569 O O   . HIS B 2 105 ? 122.913 117.809 101.353 1.00 42.04  ? 121 HIS H O   1 
ATOM 1570 C CB  . HIS B 2 105 ? 121.176 116.532 103.315 1.00 42.04  ? 121 HIS H CB  1 
ATOM 1571 C CG  . HIS B 2 105 ? 119.831 116.606 102.667 1.00 42.04  ? 121 HIS H CG  1 
ATOM 1572 N ND1 . HIS B 2 105 ? 118.694 116.970 103.353 1.00 42.04  ? 121 HIS H ND1 1 
ATOM 1573 C CD2 . HIS B 2 105 ? 119.440 116.356 101.396 1.00 42.04  ? 121 HIS H CD2 1 
ATOM 1574 C CE1 . HIS B 2 105 ? 117.661 116.946 102.531 1.00 42.04  ? 121 HIS H CE1 1 
ATOM 1575 N NE2 . HIS B 2 105 ? 118.087 116.577 101.337 1.00 42.04  ? 121 HIS H NE2 1 
ATOM 1576 N N   . TYR B 2 106 ? 121.703 119.660 101.744 1.00 39.44  ? 122 TYR H N   1 
ATOM 1577 C CA  . TYR B 2 106 ? 121.982 120.164 100.404 1.00 39.44  ? 122 TYR H CA  1 
ATOM 1578 C C   . TYR B 2 106 ? 122.304 121.655 100.337 1.00 39.44  ? 122 TYR H C   1 
ATOM 1579 O O   . TYR B 2 106 ? 122.400 122.194 99.228  1.00 39.44  ? 122 TYR H O   1 
ATOM 1580 C CB  . TYR B 2 106 ? 120.811 119.845 99.462  1.00 39.44  ? 122 TYR H CB  1 
ATOM 1581 C CG  . TYR B 2 106 ? 119.529 120.589 99.757  1.00 39.44  ? 122 TYR H CG  1 
ATOM 1582 C CD1 . TYR B 2 106 ? 119.247 121.798 99.140  1.00 39.44  ? 122 TYR H CD1 1 
ATOM 1583 C CD2 . TYR B 2 106 ? 118.594 120.074 100.640 1.00 39.44  ? 122 TYR H CD2 1 
ATOM 1584 C CE1 . TYR B 2 106 ? 118.080 122.476 99.401  1.00 39.44  ? 122 TYR H CE1 1 
ATOM 1585 C CE2 . TYR B 2 106 ? 117.423 120.745 100.907 1.00 39.44  ? 122 TYR H CE2 1 
ATOM 1586 C CZ  . TYR B 2 106 ? 117.170 121.946 100.286 1.00 39.44  ? 122 TYR H CZ  1 
ATOM 1587 O OH  . TYR B 2 106 ? 116.002 122.618 100.551 1.00 39.44  ? 122 TYR H OH  1 
ATOM 1588 N N   . THR B 2 107 ? 122.480 122.342 101.462 1.00 42.52  ? 123 THR H N   1 
ATOM 1589 C CA  . THR B 2 107 ? 122.897 123.738 101.449 1.00 42.52  ? 123 THR H CA  1 
ATOM 1590 C C   . THR B 2 107 ? 124.184 123.908 102.243 1.00 42.52  ? 123 THR H C   1 
ATOM 1591 O O   . THR B 2 107 ? 124.412 123.221 103.243 1.00 42.52  ? 123 THR H O   1 
ATOM 1592 C CB  . THR B 2 107 ? 121.823 124.673 102.019 1.00 42.52  ? 123 THR H CB  1 
ATOM 1593 O OG1 . THR B 2 107 ? 121.802 124.570 103.447 1.00 42.52  ? 123 THR H OG1 1 
ATOM 1594 C CG2 . THR B 2 107 ? 120.452 124.344 101.451 1.00 42.52  ? 123 THR H CG2 1 
ATOM 1595 N N   . TYR B 2 108 ? 125.021 124.841 101.789 1.00 39.51  ? 124 TYR H N   1 
ATOM 1596 C CA  . TYR B 2 108 ? 126.339 125.078 102.365 1.00 39.51  ? 124 TYR H CA  1 
ATOM 1597 C C   . TYR B 2 108 ? 126.418 126.431 103.061 1.00 39.51  ? 124 TYR H C   1 
ATOM 1598 O O   . TYR B 2 108 ? 127.509 126.951 103.298 1.00 39.51  ? 124 TYR H O   1 
ATOM 1599 C CB  . TYR B 2 108 ? 127.423 124.967 101.294 1.00 39.51  ? 124 TYR H CB  1 
ATOM 1600 C CG  . TYR B 2 108 ? 127.295 123.742 100.422 1.00 39.51  ? 124 TYR H CG  1 
ATOM 1601 C CD1 . TYR B 2 108 ? 126.513 123.757 99.280  1.00 39.51  ? 124 TYR H CD1 1 
ATOM 1602 C CD2 . TYR B 2 108 ? 127.953 122.567 100.747 1.00 39.51  ? 124 TYR H CD2 1 
ATOM 1603 C CE1 . TYR B 2 108 ? 126.393 122.640 98.486  1.00 39.51  ? 124 TYR H CE1 1 
ATOM 1604 C CE2 . TYR B 2 108 ? 127.838 121.445 99.958  1.00 39.51  ? 124 TYR H CE2 1 
ATOM 1605 C CZ  . TYR B 2 108 ? 127.055 121.486 98.830  1.00 39.51  ? 124 TYR H CZ  1 
ATOM 1606 O OH  . TYR B 2 108 ? 126.935 120.369 98.039  1.00 39.51  ? 124 TYR H OH  1 
ATOM 1607 N N   . ASP B 2 109 ? 125.271 127.015 103.398 1.00 47.42  ? 125 ASP H N   1 
ATOM 1608 C CA  . ASP B 2 109 ? 125.227 128.302 104.078 1.00 47.42  ? 125 ASP H CA  1 
ATOM 1609 C C   . ASP B 2 109 ? 124.901 128.146 105.557 1.00 47.42  ? 125 ASP H C   1 
ATOM 1610 O O   . ASP B 2 109 ? 125.663 128.607 106.411 1.00 47.42  ? 125 ASP H O   1 
ATOM 1611 C CB  . ASP B 2 109 ? 124.205 129.222 103.397 1.00 47.42  ? 125 ASP H CB  1 
ATOM 1612 C CG  . ASP B 2 109 ? 124.508 130.691 103.615 1.00 47.42  ? 125 ASP H CG  1 
ATOM 1613 O OD1 . ASP B 2 109 ? 124.217 131.500 102.709 1.00 47.42  ? 125 ASP H OD1 1 
ATOM 1614 O OD2 . ASP B 2 109 ? 125.035 131.039 104.692 1.00 47.42  ? 125 ASP H OD2 1 
ATOM 1615 N N   . GLY B 2 110 ? 123.787 127.501 105.884 1.00 46.54  ? 126 GLY H N   1 
ATOM 1616 C CA  . GLY B 2 110 ? 123.433 127.283 107.270 1.00 46.54  ? 126 GLY H CA  1 
ATOM 1617 C C   . GLY B 2 110 ? 124.119 126.070 107.859 1.00 46.54  ? 126 GLY H C   1 
ATOM 1618 O O   . GLY B 2 110 ? 123.828 124.939 107.468 1.00 46.54  ? 126 GLY H O   1 
ATOM 1619 N N   . TYR B 2 111 ? 125.047 126.296 108.790 1.00 45.05  ? 127 TYR H N   1 
ATOM 1620 C CA  . TYR B 2 111 ? 125.718 125.214 109.501 1.00 45.05  ? 127 TYR H CA  1 
ATOM 1621 C C   . TYR B 2 111 ? 125.836 125.529 110.984 1.00 45.05  ? 127 TYR H C   1 
ATOM 1622 O O   . TYR B 2 111 ? 126.762 125.059 111.650 1.00 45.05  ? 127 TYR H O   1 
ATOM 1623 C CB  . TYR B 2 111 ? 127.110 124.945 108.928 1.00 45.05  ? 127 TYR H CB  1 
ATOM 1624 C CG  . TYR B 2 111 ? 127.137 123.980 107.768 1.00 45.05  ? 127 TYR H CG  1 
ATOM 1625 C CD1 . TYR B 2 111 ? 126.480 122.763 107.836 1.00 45.05  ? 127 TYR H CD1 1 
ATOM 1626 C CD2 . TYR B 2 111 ? 127.839 124.280 106.610 1.00 45.05  ? 127 TYR H CD2 1 
ATOM 1627 C CE1 . TYR B 2 111 ? 126.509 121.880 106.781 1.00 45.05  ? 127 TYR H CE1 1 
ATOM 1628 C CE2 . TYR B 2 111 ? 127.874 123.402 105.552 1.00 45.05  ? 127 TYR H CE2 1 
ATOM 1629 C CZ  . TYR B 2 111 ? 127.208 122.205 105.642 1.00 45.05  ? 127 TYR H CZ  1 
ATOM 1630 O OH  . TYR B 2 111 ? 127.241 121.326 104.584 1.00 45.05  ? 127 TYR H OH  1 
ATOM 1631 N N   . TYR B 2 112 ? 124.913 126.322 111.514 1.00 47.42  ? 128 TYR H N   1 
ATOM 1632 C CA  . TYR B 2 112 ? 125.013 126.827 112.875 1.00 47.42  ? 128 TYR H CA  1 
ATOM 1633 C C   . TYR B 2 112 ? 124.439 125.815 113.855 1.00 47.42  ? 128 TYR H C   1 
ATOM 1634 O O   . TYR B 2 112 ? 123.285 125.397 113.722 1.00 47.42  ? 128 TYR H O   1 
ATOM 1635 C CB  . TYR B 2 112 ? 124.286 128.165 112.989 1.00 47.42  ? 128 TYR H CB  1 
ATOM 1636 C CG  . TYR B 2 112 ? 124.576 129.087 111.830 1.00 47.42  ? 128 TYR H CG  1 
ATOM 1637 C CD1 . TYR B 2 112 ? 125.801 129.725 111.718 1.00 47.42  ? 128 TYR H CD1 1 
ATOM 1638 C CD2 . TYR B 2 112 ? 123.633 129.304 110.840 1.00 47.42  ? 128 TYR H CD2 1 
ATOM 1639 C CE1 . TYR B 2 112 ? 126.074 130.562 110.658 1.00 47.42  ? 128 TYR H CE1 1 
ATOM 1640 C CE2 . TYR B 2 112 ? 123.898 130.138 109.774 1.00 47.42  ? 128 TYR H CE2 1 
ATOM 1641 C CZ  . TYR B 2 112 ? 125.120 130.764 109.690 1.00 47.42  ? 128 TYR H CZ  1 
ATOM 1642 O OH  . TYR B 2 112 ? 125.387 131.597 108.631 1.00 47.42  ? 128 TYR H OH  1 
ATOM 1643 N N   . PHE B 2 113 ? 125.248 125.426 114.836 1.00 47.49  ? 129 PHE H N   1 
ATOM 1644 C CA  . PHE B 2 113 ? 124.836 124.440 115.829 1.00 47.49  ? 129 PHE H CA  1 
ATOM 1645 C C   . PHE B 2 113 ? 123.758 125.060 116.705 1.00 47.49  ? 129 PHE H C   1 
ATOM 1646 O O   . PHE B 2 113 ? 123.998 126.076 117.363 1.00 47.49  ? 129 PHE H O   1 
ATOM 1647 C CB  . PHE B 2 113 ? 126.025 123.998 116.678 1.00 47.49  ? 129 PHE H CB  1 
ATOM 1648 C CG  . PHE B 2 113 ? 127.264 123.659 115.891 1.00 47.49  ? 129 PHE H CG  1 
ATOM 1649 C CD1 . PHE B 2 113 ? 127.194 123.246 114.575 1.00 47.49  ? 129 PHE H CD1 1 
ATOM 1650 C CD2 . PHE B 2 113 ? 128.508 123.750 116.486 1.00 47.49  ? 129 PHE H CD2 1 
ATOM 1651 C CE1 . PHE B 2 113 ? 128.337 122.947 113.870 1.00 47.49  ? 129 PHE H CE1 1 
ATOM 1652 C CE2 . PHE B 2 113 ? 129.651 123.446 115.786 1.00 47.49  ? 129 PHE H CE2 1 
ATOM 1653 C CZ  . PHE B 2 113 ? 129.566 123.042 114.478 1.00 47.49  ? 129 PHE H CZ  1 
ATOM 1654 N N   . ASP B 2 114 ? 122.571 124.461 116.729 1.00 48.12  ? 130 ASP H N   1 
ATOM 1655 C CA  . ASP B 2 114 ? 121.450 125.062 117.431 1.00 48.12  ? 130 ASP H CA  1 
ATOM 1656 C C   . ASP B 2 114 ? 120.814 124.178 118.493 1.00 48.12  ? 130 ASP H C   1 
ATOM 1657 O O   . ASP B 2 114 ? 120.146 124.711 119.386 1.00 48.12  ? 130 ASP H O   1 
ATOM 1658 C CB  . ASP B 2 114 ? 120.368 125.492 116.426 1.00 48.12  ? 130 ASP H CB  1 
ATOM 1659 C CG  . ASP B 2 114 ? 119.780 124.322 115.659 1.00 48.12  ? 130 ASP H CG  1 
ATOM 1660 O OD1 . ASP B 2 114 ? 120.227 123.177 115.864 1.00 48.12  ? 130 ASP H OD1 1 
ATOM 1661 O OD2 . ASP B 2 114 ? 118.868 124.552 114.837 1.00 48.12  ? 130 ASP H OD2 1 
ATOM 1662 N N   . TYR B 2 115 ? 121.031 122.867 118.454 1.00 49.00  ? 131 TYR H N   1 
ATOM 1663 C CA  . TYR B 2 115 ? 120.258 121.909 119.242 1.00 49.00  ? 131 TYR H CA  1 
ATOM 1664 C C   . TYR B 2 115 ? 121.194 120.952 119.971 1.00 49.00  ? 131 TYR H C   1 
ATOM 1665 O O   . TYR B 2 115 ? 121.047 119.731 119.908 1.00 49.00  ? 131 TYR H O   1 
ATOM 1666 C CB  . TYR B 2 115 ? 119.270 121.156 118.354 1.00 49.00  ? 131 TYR H CB  1 
ATOM 1667 C CG  . TYR B 2 115 ? 117.958 121.880 118.126 1.00 49.00  ? 131 TYR H CG  1 
ATOM 1668 C CD1 . TYR B 2 115 ? 116.891 121.244 117.520 1.00 49.00  ? 131 TYR H CD1 1 
ATOM 1669 C CD2 . TYR B 2 115 ? 117.777 123.186 118.547 1.00 49.00  ? 131 TYR H CD2 1 
ATOM 1670 C CE1 . TYR B 2 115 ? 115.695 121.898 117.312 1.00 49.00  ? 131 TYR H CE1 1 
ATOM 1671 C CE2 . TYR B 2 115 ? 116.586 123.847 118.348 1.00 49.00  ? 131 TYR H CE2 1 
ATOM 1672 C CZ  . TYR B 2 115 ? 115.547 123.198 117.733 1.00 49.00  ? 131 TYR H CZ  1 
ATOM 1673 O OH  . TYR B 2 115 ? 114.355 123.852 117.533 1.00 49.00  ? 131 TYR H OH  1 
ATOM 1674 N N   . TRP B 2 116 ? 122.189 121.515 120.655 1.00 49.85  ? 132 TRP H N   1 
ATOM 1675 C CA  . TRP B 2 116 ? 123.185 120.730 121.375 1.00 49.85  ? 132 TRP H CA  1 
ATOM 1676 C C   . TRP B 2 116 ? 122.534 119.772 122.363 1.00 49.85  ? 132 TRP H C   1 
ATOM 1677 O O   . TRP B 2 116 ? 121.607 120.141 123.087 1.00 49.85  ? 132 TRP H O   1 
ATOM 1678 C CB  . TRP B 2 116 ? 124.133 121.659 122.136 1.00 49.85  ? 132 TRP H CB  1 
ATOM 1679 C CG  . TRP B 2 116 ? 124.782 122.729 121.326 1.00 49.85  ? 132 TRP H CG  1 
ATOM 1680 C CD1 . TRP B 2 116 ? 124.170 123.780 120.717 1.00 49.85  ? 132 TRP H CD1 1 
ATOM 1681 C CD2 . TRP B 2 116 ? 126.182 122.890 121.092 1.00 49.85  ? 132 TRP H CD2 1 
ATOM 1682 N NE1 . TRP B 2 116 ? 125.098 124.569 120.088 1.00 49.85  ? 132 TRP H NE1 1 
ATOM 1683 C CE2 . TRP B 2 116 ? 126.344 124.045 120.308 1.00 49.85  ? 132 TRP H CE2 1 
ATOM 1684 C CE3 . TRP B 2 116 ? 127.315 122.162 121.459 1.00 49.85  ? 132 TRP H CE3 1 
ATOM 1685 C CZ2 . TRP B 2 116 ? 127.590 124.488 119.884 1.00 49.85  ? 132 TRP H CZ2 1 
ATOM 1686 C CZ3 . TRP B 2 116 ? 128.549 122.603 121.039 1.00 49.85  ? 132 TRP H CZ3 1 
ATOM 1687 C CH2 . TRP B 2 116 ? 128.679 123.754 120.259 1.00 49.85  ? 132 TRP H CH2 1 
ATOM 1688 N N   . GLY B 2 117 ? 123.034 118.537 122.396 1.00 58.09  ? 133 GLY H N   1 
ATOM 1689 C CA  . GLY B 2 117 ? 122.702 117.610 123.454 1.00 58.09  ? 133 GLY H CA  1 
ATOM 1690 C C   . GLY B 2 117 ? 123.646 117.762 124.633 1.00 58.09  ? 133 GLY H C   1 
ATOM 1691 O O   . GLY B 2 117 ? 124.578 118.563 124.624 1.00 58.09  ? 133 GLY H O   1 
ATOM 1692 N N   . GLN B 2 118 ? 123.395 116.966 125.668 1.00 63.26  ? 134 GLN H N   1 
ATOM 1693 C CA  . GLN B 2 118 ? 124.225 117.025 126.861 1.00 63.26  ? 134 GLN H CA  1 
ATOM 1694 C C   . GLN B 2 118 ? 125.578 116.368 126.589 1.00 63.26  ? 134 GLN H C   1 
ATOM 1695 O O   . GLN B 2 118 ? 125.874 115.927 125.476 1.00 63.26  ? 134 GLN H O   1 
ATOM 1696 C CB  . GLN B 2 118 ? 123.506 116.379 128.044 1.00 63.26  ? 134 GLN H CB  1 
ATOM 1697 C CG  . GLN B 2 118 ? 123.025 114.962 127.799 1.00 63.26  ? 134 GLN H CG  1 
ATOM 1698 C CD  . GLN B 2 118 ? 121.663 114.919 127.134 1.00 63.26  ? 134 GLN H CD  1 
ATOM 1699 O OE1 . GLN B 2 118 ? 121.506 115.358 125.995 1.00 63.26  ? 134 GLN H OE1 1 
ATOM 1700 N NE2 . GLN B 2 118 ? 120.671 114.394 127.842 1.00 63.26  ? 134 GLN H NE2 1 
ATOM 1701 N N   . GLY B 2 119 ? 126.422 116.307 127.620 1.00 64.07  ? 135 GLY H N   1 
ATOM 1702 C CA  . GLY B 2 119 ? 127.778 115.828 127.461 1.00 64.07  ? 135 GLY H CA  1 
ATOM 1703 C C   . GLY B 2 119 ? 127.948 114.366 127.831 1.00 64.07  ? 135 GLY H C   1 
ATOM 1704 O O   . GLY B 2 119 ? 126.993 113.639 128.097 1.00 64.07  ? 135 GLY H O   1 
ATOM 1705 N N   . THR B 2 120 ? 129.209 113.937 127.835 1.00 66.19  ? 136 THR H N   1 
ATOM 1706 C CA  . THR B 2 120 ? 129.590 112.597 128.260 1.00 66.19  ? 136 THR H CA  1 
ATOM 1707 C C   . THR B 2 120 ? 130.627 112.575 129.369 1.00 66.19  ? 136 THR H C   1 
ATOM 1708 O O   . THR B 2 120 ? 130.616 111.645 130.176 1.00 66.19  ? 136 THR H O   1 
ATOM 1709 C CB  . THR B 2 120 ? 130.131 111.780 127.077 1.00 66.19  ? 136 THR H CB  1 
ATOM 1710 O OG1 . THR B 2 120 ? 131.286 112.429 126.535 1.00 66.19  ? 136 THR H OG1 1 
ATOM 1711 C CG2 . THR B 2 120 ? 129.076 111.624 126.004 1.00 66.19  ? 136 THR H CG2 1 
ATOM 1712 N N   . THR B 2 121 ? 131.521 113.564 129.432 1.00 68.83  ? 137 THR H N   1 
ATOM 1713 C CA  . THR B 2 121 ? 132.512 113.684 130.502 1.00 68.83  ? 137 THR H CA  1 
ATOM 1714 C C   . THR B 2 121 ? 133.386 112.428 130.589 1.00 68.83  ? 137 THR H C   1 
ATOM 1715 O O   . THR B 2 121 ? 133.363 111.679 131.566 1.00 68.83  ? 137 THR H O   1 
ATOM 1716 C CB  . THR B 2 121 ? 131.841 113.979 131.850 1.00 68.83  ? 137 THR H CB  1 
ATOM 1717 O OG1 . THR B 2 121 ? 131.290 112.769 132.385 1.00 68.83  ? 137 THR H OG1 1 
ATOM 1718 C CG2 . THR B 2 121 ? 130.737 115.017 131.696 1.00 68.83  ? 137 THR H CG2 1 
ATOM 1719 N N   . LEU B 2 122 ? 134.148 112.207 129.519 1.00 69.33  ? 138 LEU H N   1 
ATOM 1720 C CA  . LEU B 2 122 ? 135.107 111.112 129.509 1.00 69.33  ? 138 LEU H CA  1 
ATOM 1721 C C   . LEU B 2 122 ? 136.158 111.300 130.595 1.00 69.33  ? 138 LEU H C   1 
ATOM 1722 O O   . LEU B 2 122 ? 136.577 112.419 130.902 1.00 69.33  ? 138 LEU H O   1 
ATOM 1723 C CB  . LEU B 2 122 ? 135.797 111.003 128.151 1.00 69.33  ? 138 LEU H CB  1 
ATOM 1724 C CG  . LEU B 2 122 ? 135.174 110.043 127.143 1.00 69.33  ? 138 LEU H CG  1 
ATOM 1725 C CD1 . LEU B 2 122 ? 135.977 110.039 125.860 1.00 69.33  ? 138 LEU H CD1 1 
ATOM 1726 C CD2 . LEU B 2 122 ? 135.100 108.648 127.733 1.00 69.33  ? 138 LEU H CD2 1 
ATOM 1727 N N   . THR B 2 123 ? 136.581 110.183 131.182 1.00 71.77  ? 139 THR H N   1 
ATOM 1728 C CA  . THR B 2 123 ? 137.614 110.166 132.205 1.00 71.77  ? 139 THR H CA  1 
ATOM 1729 C C   . THR B 2 123 ? 138.638 109.094 131.868 1.00 71.77  ? 139 THR H C   1 
ATOM 1730 O O   . THR B 2 123 ? 138.277 107.971 131.505 1.00 71.77  ? 139 THR H O   1 
ATOM 1731 C CB  . THR B 2 123 ? 137.025 109.901 133.596 1.00 71.77  ? 139 THR H CB  1 
ATOM 1732 O OG1 . THR B 2 123 ? 136.332 108.647 133.590 1.00 71.77  ? 139 THR H OG1 1 
ATOM 1733 C CG2 . THR B 2 123 ? 136.062 111.006 133.995 1.00 71.77  ? 139 THR H CG2 1 
ATOM 1734 N N   . VAL B 2 124 ? 139.914 109.445 131.987 1.00 71.34  ? 140 VAL H N   1 
ATOM 1735 C CA  . VAL B 2 124 ? 140.992 108.508 131.702 1.00 71.34  ? 140 VAL H CA  1 
ATOM 1736 C C   . VAL B 2 124 ? 141.933 108.410 132.896 1.00 71.34  ? 140 VAL H C   1 
ATOM 1737 O O   . VAL B 2 124 ? 142.463 107.341 133.196 1.00 71.34  ? 140 VAL H O   1 
ATOM 1738 C CB  . VAL B 2 124 ? 141.764 108.916 130.439 1.00 71.34  ? 140 VAL H CB  1 
ATOM 1739 C CG1 . VAL B 2 124 ? 140.876 108.800 129.216 1.00 71.34  ? 140 VAL H CG1 1 
ATOM 1740 C CG2 . VAL B 2 124 ? 142.292 110.332 130.581 1.00 71.34  ? 140 VAL H CG2 1 
ATOM 1741 N N   . ALA C 3 2   ? 117.831 140.307 91.367  1.00 53.41  ? 1   ALA c N   1 
ATOM 1742 C CA  . ALA C 3 2   ? 117.460 141.644 90.918  1.00 53.41  ? 1   ALA c CA  1 
ATOM 1743 C C   . ALA C 3 2   ? 118.671 142.383 90.366  1.00 53.41  ? 1   ALA c C   1 
ATOM 1744 O O   . ALA C 3 2   ? 118.969 142.296 89.175  1.00 53.41  ? 1   ALA c O   1 
ATOM 1745 C CB  . ALA C 3 2   ? 116.830 142.430 92.054  1.00 53.41  ? 1   ALA c CB  1 
ATOM 1746 N N   . LYS C 3 3   ? 119.368 143.111 91.234  1.00 50.89  ? 2   LYS c N   1 
ATOM 1747 C CA  . LYS C 3 3   ? 120.572 143.844 90.864  1.00 50.89  ? 2   LYS c CA  1 
ATOM 1748 C C   . LYS C 3 3   ? 121.777 143.079 91.391  1.00 50.89  ? 2   LYS c C   1 
ATOM 1749 O O   . LYS C 3 3   ? 121.865 142.804 92.592  1.00 50.89  ? 2   LYS c O   1 
ATOM 1750 C CB  . LYS C 3 3   ? 120.543 145.270 91.412  1.00 50.89  ? 2   LYS c CB  1 
ATOM 1751 C CG  . LYS C 3 3   ? 119.337 146.104 90.961  1.00 50.89  ? 2   LYS c CG  1 
ATOM 1752 C CD  . LYS C 3 3   ? 119.400 146.480 89.480  1.00 50.89  ? 2   LYS c CD  1 
ATOM 1753 C CE  . LYS C 3 3   ? 118.526 145.576 88.618  1.00 50.89  ? 2   LYS c CE  1 
ATOM 1754 N NZ  . LYS C 3 3   ? 118.557 145.984 87.191  1.00 50.89  ? 2   LYS c NZ  1 
ATOM 1755 N N   . LEU C 3 4   ? 122.696 142.740 90.493  1.00 45.37  ? 3   LEU c N   1 
ATOM 1756 C CA  . LEU C 3 4   ? 123.785 141.839 90.842  1.00 45.37  ? 3   LEU c CA  1 
ATOM 1757 C C   . LEU C 3 4   ? 124.837 142.546 91.687  1.00 45.37  ? 3   LEU c C   1 
ATOM 1758 O O   . LEU C 3 4   ? 125.174 143.709 91.453  1.00 45.37  ? 3   LEU c O   1 
ATOM 1759 C CB  . LEU C 3 4   ? 124.416 141.254 89.575  1.00 45.37  ? 3   LEU c CB  1 
ATOM 1760 C CG  . LEU C 3 4   ? 125.294 142.118 88.668  1.00 45.37  ? 3   LEU c CG  1 
ATOM 1761 C CD1 . LEU C 3 4   ? 126.082 141.235 87.718  1.00 45.37  ? 3   LEU c CD1 1 
ATOM 1762 C CD2 . LEU C 3 4   ? 124.476 143.131 87.885  1.00 45.37  ? 3   LEU c CD2 1 
ATOM 1763 N N   . GLU C 3 5   ? 125.342 141.830 92.688  1.00 41.94  ? 4   GLU c N   1 
ATOM 1764 C CA  . GLU C 3 5   ? 126.411 142.303 93.557  1.00 41.94  ? 4   GLU c CA  1 
ATOM 1765 C C   . GLU C 3 5   ? 127.325 141.115 93.843  1.00 41.94  ? 4   GLU c C   1 
ATOM 1766 O O   . GLU C 3 5   ? 127.198 140.052 93.229  1.00 41.94  ? 4   GLU c O   1 
ATOM 1767 C CB  . GLU C 3 5   ? 125.831 142.939 94.828  1.00 41.94  ? 4   GLU c CB  1 
ATOM 1768 C CG  . GLU C 3 5   ? 126.750 143.946 95.518  1.00 41.94  ? 4   GLU c CG  1 
ATOM 1769 C CD  . GLU C 3 5   ? 126.826 145.278 94.793  1.00 41.94  ? 4   GLU c CD  1 
ATOM 1770 O OE1 . GLU C 3 5   ? 125.887 146.087 94.941  1.00 41.94  ? 4   GLU c OE1 1 
ATOM 1771 O OE2 . GLU C 3 5   ? 127.828 145.520 94.085  1.00 41.94  ? 4   GLU c OE2 1 
ATOM 1772 N N   . THR C 3 6   ? 128.255 141.292 94.778  1.00 37.23  ? 5   THR c N   1 
ATOM 1773 C CA  . THR C 3 6   ? 129.201 140.232 95.101  1.00 37.23  ? 5   THR c CA  1 
ATOM 1774 C C   . THR C 3 6   ? 128.482 139.015 95.671  1.00 37.23  ? 5   THR c C   1 
ATOM 1775 O O   . THR C 3 6   ? 127.548 139.138 96.468  1.00 37.23  ? 5   THR c O   1 
ATOM 1776 C CB  . THR C 3 6   ? 130.250 140.746 96.089  1.00 37.23  ? 5   THR c CB  1 
ATOM 1777 O OG1 . THR C 3 6   ? 131.095 139.666 96.502  1.00 37.23  ? 5   THR c OG1 1 
ATOM 1778 C CG2 . THR C 3 6   ? 129.589 141.370 97.304  1.00 37.23  ? 5   THR c CG2 1 
ATOM 1779 N N   . VAL C 3 7   ? 128.917 137.831 95.247  1.00 35.18  ? 6   VAL c N   1 
ATOM 1780 C CA  . VAL C 3 7   ? 128.318 136.564 95.655  1.00 35.18  ? 6   VAL c CA  1 
ATOM 1781 C C   . VAL C 3 7   ? 129.388 135.742 96.358  1.00 35.18  ? 6   VAL c C   1 
ATOM 1782 O O   . VAL C 3 7   ? 130.441 135.461 95.776  1.00 35.18  ? 6   VAL c O   1 
ATOM 1783 C CB  . VAL C 3 7   ? 127.741 135.797 94.457  1.00 35.18  ? 6   VAL c CB  1 
ATOM 1784 C CG1 . VAL C 3 7   ? 127.488 134.351 94.829  1.00 35.18  ? 6   VAL c CG1 1 
ATOM 1785 C CG2 . VAL C 3 7   ? 126.465 136.453 93.973  1.00 35.18  ? 6   VAL c CG2 1 
ATOM 1786 N N   . THR C 3 8   ? 129.120 135.342 97.594  1.00 37.60  ? 7   THR c N   1 
ATOM 1787 C CA  . THR C 3 8   ? 130.094 134.630 98.410  1.00 37.60  ? 7   THR c CA  1 
ATOM 1788 C C   . THR C 3 8   ? 129.614 133.206 98.648  1.00 37.60  ? 7   THR c C   1 
ATOM 1789 O O   . THR C 3 8   ? 128.498 132.998 99.135  1.00 37.60  ? 7   THR c O   1 
ATOM 1790 C CB  . THR C 3 8   ? 130.312 135.345 99.739  1.00 37.60  ? 7   THR c CB  1 
ATOM 1791 O OG1 . THR C 3 8   ? 129.145 135.196 100.554 1.00 37.60  ? 7   THR c OG1 1 
ATOM 1792 C CG2 . THR C 3 8   ? 130.560 136.820 99.498  1.00 37.60  ? 7   THR c CG2 1 
ATOM 1793 N N   . LEU C 3 9   ? 130.456 132.232 98.313  1.00 36.26  ? 8   LEU c N   1 
ATOM 1794 C CA  . LEU C 3 9   ? 130.170 130.822 98.524  1.00 36.26  ? 8   LEU c CA  1 
ATOM 1795 C C   . LEU C 3 9   ? 131.235 130.248 99.443  1.00 36.26  ? 8   LEU c C   1 
ATOM 1796 O O   . LEU C 3 9   ? 132.432 130.394 99.176  1.00 36.26  ? 8   LEU c O   1 
ATOM 1797 C CB  . LEU C 3 9   ? 130.148 130.066 97.196  1.00 36.26  ? 8   LEU c CB  1 
ATOM 1798 C CG  . LEU C 3 9   ? 129.203 130.624 96.134  1.00 36.26  ? 8   LEU c CG  1 
ATOM 1799 C CD1 . LEU C 3 9   ? 129.200 129.742 94.903  1.00 36.26  ? 8   LEU c CD1 1 
ATOM 1800 C CD2 . LEU C 3 9   ? 127.804 130.763 96.697  1.00 36.26  ? 8   LEU c CD2 1 
ATOM 1801 N N   . GLY C 3 10  ? 130.804 129.596 100.522 1.00 37.68  ? 9   GLY c N   1 
ATOM 1802 C CA  . GLY C 3 10  ? 131.725 129.052 101.490 1.00 37.68  ? 9   GLY c CA  1 
ATOM 1803 C C   . GLY C 3 10  ? 131.453 127.582 101.738 1.00 37.68  ? 9   GLY c C   1 
ATOM 1804 O O   . GLY C 3 10  ? 130.380 127.063 101.435 1.00 37.68  ? 9   GLY c O   1 
ATOM 1805 N N   . ASN C 3 11  ? 132.463 126.916 102.298 1.00 38.06  ? 10  ASN c N   1 
ATOM 1806 C CA  . ASN C 3 11  ? 132.395 125.493 102.627 1.00 38.06  ? 10  ASN c CA  1 
ATOM 1807 C C   . ASN C 3 11  ? 132.110 124.638 101.399 1.00 38.06  ? 10  ASN c C   1 
ATOM 1808 O O   . ASN C 3 11  ? 131.471 123.590 101.497 1.00 38.06  ? 10  ASN c O   1 
ATOM 1809 C CB  . ASN C 3 11  ? 131.353 125.220 103.712 1.00 38.06  ? 10  ASN c CB  1 
ATOM 1810 C CG  . ASN C 3 11  ? 131.359 126.266 104.797 1.00 38.06  ? 10  ASN c CG  1 
ATOM 1811 O OD1 . ASN C 3 11  ? 132.226 126.268 105.667 1.00 38.06  ? 10  ASN c OD1 1 
ATOM 1812 N ND2 . ASN C 3 11  ? 130.386 127.165 104.756 1.00 38.06  ? 10  ASN c ND2 1 
ATOM 1813 N N   . ILE C 3 12  ? 132.582 125.072 100.230 1.00 37.68  ? 11  ILE c N   1 
ATOM 1814 C CA  . ILE C 3 12  ? 132.322 124.303 99.022  1.00 37.68  ? 11  ILE c CA  1 
ATOM 1815 C C   . ILE C 3 12  ? 133.207 123.060 98.982  1.00 37.68  ? 11  ILE c C   1 
ATOM 1816 O O   . ILE C 3 12  ? 134.102 122.862 99.809  1.00 37.68  ? 11  ILE c O   1 
ATOM 1817 C CB  . ILE C 3 12  ? 132.480 125.167 97.761  1.00 37.68  ? 11  ILE c CB  1 
ATOM 1818 C CG1 . ILE C 3 12  ? 133.852 125.818 97.708  1.00 37.68  ? 11  ILE c CG1 1 
ATOM 1819 C CG2 . ILE C 3 12  ? 131.397 126.225 97.706  1.00 37.68  ? 11  ILE c CG2 1 
ATOM 1820 C CD1 . ILE C 3 12  ? 134.038 126.644 96.474  1.00 37.68  ? 11  ILE c CD1 1 
ATOM 1821 N N   . GLY C 3 13  ? 132.958 122.224 97.983  1.00 41.90  ? 12  GLY c N   1 
ATOM 1822 C CA  . GLY C 3 13  ? 132.945 120.789 98.165  1.00 41.90  ? 12  GLY c CA  1 
ATOM 1823 C C   . GLY C 3 13  ? 134.288 120.098 98.258  1.00 41.90  ? 12  GLY c C   1 
ATOM 1824 O O   . GLY C 3 13  ? 135.351 120.703 98.406  1.00 41.90  ? 12  GLY c O   1 
ATOM 1825 N N   . LYS C 3 14  ? 134.198 118.766 98.173  1.00 45.24  ? 13  LYS c N   1 
ATOM 1826 C CA  . LYS C 3 14  ? 135.243 117.776 98.410  1.00 45.24  ? 13  LYS c CA  1 
ATOM 1827 C C   . LYS C 3 14  ? 135.477 117.620 99.907  1.00 45.24  ? 13  LYS c C   1 
ATOM 1828 O O   . LYS C 3 14  ? 135.186 116.565 100.479 1.00 45.24  ? 13  LYS c O   1 
ATOM 1829 C CB  . LYS C 3 14  ? 136.547 118.115 97.689  1.00 45.24  ? 13  LYS c CB  1 
ATOM 1830 C CG  . LYS C 3 14  ? 137.607 117.062 97.921  1.00 45.24  ? 13  LYS c CG  1 
ATOM 1831 C CD  . LYS C 3 14  ? 137.212 115.775 97.214  1.00 45.24  ? 13  LYS c CD  1 
ATOM 1832 C CE  . LYS C 3 14  ? 138.283 114.708 97.319  1.00 45.24  ? 13  LYS c CE  1 
ATOM 1833 N NZ  . LYS C 3 14  ? 137.840 113.440 96.676  1.00 45.24  ? 13  LYS c NZ  1 
ATOM 1834 N N   . ASP C 3 15  ? 135.995 118.667 100.550 1.00 46.65  ? 14  ASP c N   1 
ATOM 1835 C CA  . ASP C 3 15  ? 136.308 118.594 101.972 1.00 46.65  ? 14  ASP c CA  1 
ATOM 1836 C C   . ASP C 3 15  ? 135.908 119.857 102.727 1.00 46.65  ? 14  ASP c C   1 
ATOM 1837 O O   . ASP C 3 15  ? 136.250 119.995 103.906 1.00 46.65  ? 14  ASP c O   1 
ATOM 1838 C CB  . ASP C 3 15  ? 137.796 118.320 102.158 1.00 46.65  ? 14  ASP c CB  1 
ATOM 1839 C CG  . ASP C 3 15  ? 138.658 119.289 101.382 1.00 46.65  ? 14  ASP c CG  1 
ATOM 1840 O OD1 . ASP C 3 15  ? 139.772 119.602 101.844 1.00 46.65  ? 14  ASP c OD1 1 
ATOM 1841 O OD2 . ASP C 3 15  ? 138.217 119.742 100.306 1.00 46.65  ? 14  ASP c OD2 1 
ATOM 1842 N N   . GLY C 3 16  ? 135.197 120.780 102.084 1.00 44.10  ? 15  GLY c N   1 
ATOM 1843 C CA  . GLY C 3 16  ? 134.736 121.975 102.764 1.00 44.10  ? 15  GLY c CA  1 
ATOM 1844 C C   . GLY C 3 16  ? 135.819 122.972 103.094 1.00 44.10  ? 15  GLY c C   1 
ATOM 1845 O O   . GLY C 3 16  ? 135.578 123.900 103.867 1.00 44.10  ? 15  GLY c O   1 
ATOM 1846 N N   . LYS C 3 17  ? 137.005 122.821 102.514 1.00 45.14  ? 16  LYS c N   1 
ATOM 1847 C CA  . LYS C 3 17  ? 138.147 123.648 102.872 1.00 45.14  ? 16  LYS c CA  1 
ATOM 1848 C C   . LYS C 3 17  ? 138.257 124.925 102.049 1.00 45.14  ? 16  LYS c C   1 
ATOM 1849 O O   . LYS C 3 17  ? 139.089 125.779 102.374 1.00 45.14  ? 16  LYS c O   1 
ATOM 1850 C CB  . LYS C 3 17  ? 139.443 122.839 102.724 1.00 45.14  ? 16  LYS c CB  1 
ATOM 1851 C CG  . LYS C 3 17  ? 140.599 123.339 103.580 1.00 45.14  ? 16  LYS c CG  1 
ATOM 1852 C CD  . LYS C 3 17  ? 141.798 122.402 103.539 1.00 45.14  ? 16  LYS c CD  1 
ATOM 1853 C CE  . LYS C 3 17  ? 141.465 120.999 104.021 1.00 45.14  ? 16  LYS c CE  1 
ATOM 1854 N NZ  . LYS C 3 17  ? 140.504 120.983 105.154 1.00 45.14  ? 16  LYS c NZ  1 
ATOM 1855 N N   . GLN C 3 18  ? 137.445 125.094 101.011 1.00 43.11  ? 17  GLN c N   1 
ATOM 1856 C CA  . GLN C 3 18  ? 137.654 126.170 100.055 1.00 43.11  ? 17  GLN c CA  1 
ATOM 1857 C C   . GLN C 3 18  ? 136.474 127.131 100.034 1.00 43.11  ? 17  GLN c C   1 
ATOM 1858 O O   . GLN C 3 18  ? 135.348 126.784 100.399 1.00 43.11  ? 17  GLN c O   1 
ATOM 1859 C CB  . GLN C 3 18  ? 137.905 125.613 98.652  1.00 43.11  ? 17  GLN c CB  1 
ATOM 1860 C CG  . GLN C 3 18  ? 138.760 124.363 98.654  1.00 43.11  ? 17  GLN c CG  1 
ATOM 1861 C CD  . GLN C 3 18  ? 138.762 123.656 97.322  1.00 43.11  ? 17  GLN c CD  1 
ATOM 1862 O OE1 . GLN C 3 18  ? 138.756 124.294 96.273  1.00 43.11  ? 17  GLN c OE1 1 
ATOM 1863 N NE2 . GLN C 3 18  ? 138.771 122.330 97.355  1.00 43.11  ? 17  GLN c NE2 1 
ATOM 1864 N N   . THR C 3 19  ? 136.763 128.357 99.606  1.00 39.96  ? 18  THR c N   1 
ATOM 1865 C CA  . THR C 3 19  ? 135.792 129.435 99.514  1.00 39.96  ? 18  THR c CA  1 
ATOM 1866 C C   . THR C 3 19  ? 135.921 130.094 98.150  1.00 39.96  ? 18  THR c C   1 
ATOM 1867 O O   . THR C 3 19  ? 136.892 129.870 97.424  1.00 39.96  ? 18  THR c O   1 
ATOM 1868 C CB  . THR C 3 19  ? 136.000 130.476 100.616 1.00 39.96  ? 18  THR c CB  1 
ATOM 1869 O OG1 . THR C 3 19  ? 137.336 130.986 100.543 1.00 39.96  ? 18  THR c OG1 1 
ATOM 1870 C CG2 . THR C 3 19  ? 135.790 129.850 101.979 1.00 39.96  ? 18  THR c CG2 1 
ATOM 1871 N N   . LEU C 3 20  ? 134.935 130.916 97.799  1.00 36.02  ? 19  LEU c N   1 
ATOM 1872 C CA  . LEU C 3 20  ? 134.914 131.522 96.472  1.00 36.02  ? 19  LEU c CA  1 
ATOM 1873 C C   . LEU C 3 20  ? 134.062 132.781 96.490  1.00 36.02  ? 19  LEU c C   1 
ATOM 1874 O O   . LEU C 3 20  ? 132.869 132.722 96.798  1.00 36.02  ? 19  LEU c O   1 
ATOM 1875 C CB  . LEU C 3 20  ? 134.398 130.512 95.444  1.00 36.02  ? 19  LEU c CB  1 
ATOM 1876 C CG  . LEU C 3 20  ? 134.446 130.837 93.955  1.00 36.02  ? 19  LEU c CG  1 
ATOM 1877 C CD1 . LEU C 3 20  ? 134.640 129.574 93.163  1.00 36.02  ? 19  LEU c CD1 1 
ATOM 1878 C CD2 . LEU C 3 20  ? 133.147 131.462 93.557  1.00 36.02  ? 19  LEU c CD2 1 
ATOM 1879 N N   . VAL C 3 21  ? 134.667 133.912 96.139  1.00 34.90  ? 20  VAL c N   1 
ATOM 1880 C CA  . VAL C 3 21  ? 133.999 135.209 96.129  1.00 34.90  ? 20  VAL c CA  1 
ATOM 1881 C C   . VAL C 3 21  ? 133.963 135.706 94.691  1.00 34.90  ? 20  VAL c C   1 
ATOM 1882 O O   . VAL C 3 21  ? 135.010 135.868 94.054  1.00 34.90  ? 20  VAL c O   1 
ATOM 1883 C CB  . VAL C 3 21  ? 134.706 136.218 97.041  1.00 34.90  ? 20  VAL c CB  1 
ATOM 1884 C CG1 . VAL C 3 21  ? 134.088 137.590 96.884  1.00 34.90  ? 20  VAL c CG1 1 
ATOM 1885 C CG2 . VAL C 3 21  ? 134.640 135.762 98.481  1.00 34.90  ? 20  VAL c CG2 1 
ATOM 1886 N N   . LEU C 3 22  ? 132.763 135.964 94.183  1.00 32.66  ? 21  LEU c N   1 
ATOM 1887 C CA  . LEU C 3 22  ? 132.554 136.419 92.818  1.00 32.66  ? 21  LEU c CA  1 
ATOM 1888 C C   . LEU C 3 22  ? 132.141 137.882 92.814  1.00 32.66  ? 21  LEU c C   1 
ATOM 1889 O O   . LEU C 3 22  ? 131.244 138.287 93.558  1.00 32.66  ? 21  LEU c O   1 
ATOM 1890 C CB  . LEU C 3 22  ? 131.479 135.582 92.129  1.00 32.66  ? 21  LEU c CB  1 
ATOM 1891 C CG  . LEU C 3 22  ? 131.832 134.135 91.805  1.00 32.66  ? 21  LEU c CG  1 
ATOM 1892 C CD1 . LEU C 3 22  ? 130.614 133.391 91.305  1.00 32.66  ? 21  LEU c CD1 1 
ATOM 1893 C CD2 . LEU C 3 22  ? 132.950 134.070 90.788  1.00 32.66  ? 21  LEU c CD2 1 
ATOM 1894 N N   . ASN C 3 23  ? 132.796 138.670 91.966  1.00 34.02  ? 22  ASN c N   1 
ATOM 1895 C CA  . ASN C 3 23  ? 132.490 140.077 91.826  1.00 34.02  ? 22  ASN c CA  1 
ATOM 1896 C C   . ASN C 3 23  ? 131.793 140.332 90.497  1.00 34.02  ? 22  ASN c C   1 
ATOM 1897 O O   . ASN C 3 23  ? 132.182 139.755 89.478  1.00 34.02  ? 22  ASN c O   1 
ATOM 1898 C CB  . ASN C 3 23  ? 133.764 140.922 91.906  1.00 34.02  ? 22  ASN c CB  1 
ATOM 1899 C CG  . ASN C 3 23  ? 134.661 140.508 93.048  1.00 34.02  ? 22  ASN c CG  1 
ATOM 1900 O OD1 . ASN C 3 23  ? 135.833 140.191 92.849  1.00 34.02  ? 22  ASN c OD1 1 
ATOM 1901 N ND2 . ASN C 3 23  ? 134.116 140.508 94.256  1.00 34.02  ? 22  ASN c ND2 1 
ATOM 1902 N N   . PRO C 3 24  ? 130.765 141.178 90.475  1.00 34.49  ? 23  PRO c N   1 
ATOM 1903 C CA  . PRO C 3 24  ? 130.055 141.441 89.220  1.00 34.49  ? 23  PRO c CA  1 
ATOM 1904 C C   . PRO C 3 24  ? 130.976 142.041 88.171  1.00 34.49  ? 23  PRO c C   1 
ATOM 1905 O O   . PRO C 3 24  ? 131.884 142.816 88.477  1.00 34.49  ? 23  PRO c O   1 
ATOM 1906 C CB  . PRO C 3 24  ? 128.960 142.428 89.636  1.00 34.49  ? 23  PRO c CB  1 
ATOM 1907 C CG  . PRO C 3 24  ? 129.470 143.042 90.891  1.00 34.49  ? 23  PRO c CG  1 
ATOM 1908 C CD  . PRO C 3 24  ? 130.189 141.939 91.593  1.00 34.49  ? 23  PRO c CD  1 
ATOM 1909 N N   . ARG C 3 25  ? 130.732 141.668 86.914  1.00 34.82  ? 24  ARG c N   1 
ATOM 1910 C CA  . ARG C 3 25  ? 131.581 142.093 85.808  1.00 34.82  ? 24  ARG c CA  1 
ATOM 1911 C C   . ARG C 3 25  ? 130.774 142.737 84.685  1.00 34.82  ? 24  ARG c C   1 
ATOM 1912 O O   . ARG C 3 25  ? 131.245 142.800 83.546  1.00 34.82  ? 24  ARG c O   1 
ATOM 1913 C CB  . ARG C 3 25  ? 132.399 140.911 85.283  1.00 34.82  ? 24  ARG c CB  1 
ATOM 1914 C CG  . ARG C 3 25  ? 133.707 141.294 84.614  1.00 34.82  ? 24  ARG c CG  1 
ATOM 1915 C CD  . ARG C 3 25  ? 134.580 142.131 85.533  1.00 34.82  ? 24  ARG c CD  1 
ATOM 1916 N NE  . ARG C 3 25  ? 135.023 141.406 86.717  1.00 34.82  ? 24  ARG c NE  1 
ATOM 1917 C CZ  . ARG C 3 25  ? 136.176 140.759 86.806  1.00 34.82  ? 24  ARG c CZ  1 
ATOM 1918 N NH1 . ARG C 3 25  ? 137.019 140.704 85.788  1.00 34.82  ? 24  ARG c NH1 1 
ATOM 1919 N NH2 . ARG C 3 25  ? 136.495 140.156 87.947  1.00 34.82  ? 24  ARG c NH2 1 
ATOM 1920 N N   . GLY C 3 26  ? 129.566 143.209 84.976  1.00 35.73  ? 25  GLY c N   1 
ATOM 1921 C CA  . GLY C 3 26  ? 128.812 143.988 84.014  1.00 35.73  ? 25  GLY c CA  1 
ATOM 1922 C C   . GLY C 3 26  ? 127.932 143.179 83.086  1.00 35.73  ? 25  GLY c C   1 
ATOM 1923 O O   . GLY C 3 26  ? 128.316 142.098 82.636  1.00 35.73  ? 25  GLY c O   1 
ATOM 1924 N N   . VAL C 3 27  ? 126.750 143.706 82.786  1.00 39.13  ? 26  VAL c N   1 
ATOM 1925 C CA  . VAL C 3 27  ? 125.805 143.031 81.905  1.00 39.13  ? 26  VAL c CA  1 
ATOM 1926 C C   . VAL C 3 27  ? 126.161 143.332 80.457  1.00 39.13  ? 26  VAL c C   1 
ATOM 1927 O O   . VAL C 3 27  ? 126.326 144.496 80.074  1.00 39.13  ? 26  VAL c O   1 
ATOM 1928 C CB  . VAL C 3 27  ? 124.366 143.467 82.218  1.00 39.13  ? 26  VAL c CB  1 
ATOM 1929 C CG1 . VAL C 3 27  ? 123.401 142.822 81.246  1.00 39.13  ? 26  VAL c CG1 1 
ATOM 1930 C CG2 . VAL C 3 27  ? 124.004 143.112 83.646  1.00 39.13  ? 26  VAL c CG2 1 
ATOM 1931 N N   . ASN C 3 28  ? 126.284 142.286 79.652  1.00 42.01  ? 27  ASN c N   1 
ATOM 1932 C CA  . ASN C 3 28  ? 126.473 142.466 78.219  1.00 42.01  ? 27  ASN c CA  1 
ATOM 1933 C C   . ASN C 3 28  ? 125.210 143.072 77.619  1.00 42.01  ? 27  ASN c C   1 
ATOM 1934 O O   . ASN C 3 28  ? 124.106 142.604 77.914  1.00 42.01  ? 27  ASN c O   1 
ATOM 1935 C CB  . ASN C 3 28  ? 126.791 141.128 77.556  1.00 42.01  ? 27  ASN c CB  1 
ATOM 1936 C CG  . ASN C 3 28  ? 127.137 141.268 76.087  1.00 42.01  ? 27  ASN c CG  1 
ATOM 1937 O OD1 . ASN C 3 28  ? 126.301 141.652 75.271  1.00 42.01  ? 27  ASN c OD1 1 
ATOM 1938 N ND2 . ASN C 3 28  ? 128.377 140.946 75.742  1.00 42.01  ? 27  ASN c ND2 1 
ATOM 1939 N N   . PRO C 3 29  ? 125.321 144.110 76.784  1.00 42.02  ? 28  PRO c N   1 
ATOM 1940 C CA  . PRO C 3 29  ? 124.118 144.767 76.262  1.00 42.02  ? 28  PRO c CA  1 
ATOM 1941 C C   . PRO C 3 29  ? 123.618 144.214 74.939  1.00 42.02  ? 28  PRO c C   1 
ATOM 1942 O O   . PRO C 3 29  ? 122.503 144.564 74.531  1.00 42.02  ? 28  PRO c O   1 
ATOM 1943 C CB  . PRO C 3 29  ? 124.568 146.229 76.112  1.00 42.02  ? 28  PRO c CB  1 
ATOM 1944 C CG  . PRO C 3 29  ? 126.114 146.197 76.218  1.00 42.02  ? 28  PRO c CG  1 
ATOM 1945 C CD  . PRO C 3 29  ? 126.529 144.754 76.253  1.00 42.02  ? 28  PRO c CD  1 
ATOM 1946 N N   . THR C 3 30  ? 124.389 143.370 74.257  1.00 43.08  ? 29  THR c N   1 
ATOM 1947 C CA  . THR C 3 30  ? 123.951 142.817 72.983  1.00 43.08  ? 29  THR c CA  1 
ATOM 1948 C C   . THR C 3 30  ? 123.020 141.626 73.146  1.00 43.08  ? 29  THR c C   1 
ATOM 1949 O O   . THR C 3 30  ? 122.141 141.419 72.303  1.00 43.08  ? 29  THR c O   1 
ATOM 1950 C CB  . THR C 3 30  ? 125.159 142.401 72.141  1.00 43.08  ? 29  THR c CB  1 
ATOM 1951 O OG1 . THR C 3 30  ? 125.870 141.352 72.809  1.00 43.08  ? 29  THR c OG1 1 
ATOM 1952 C CG2 . THR C 3 30  ? 126.091 143.582 71.933  1.00 43.08  ? 29  THR c CG2 1 
ATOM 1953 N N   . ASN C 3 31  ? 123.190 140.838 74.209  1.00 42.94  ? 30  ASN c N   1 
ATOM 1954 C CA  . ASN C 3 31  ? 122.328 139.686 74.436  1.00 42.94  ? 30  ASN c CA  1 
ATOM 1955 C C   . ASN C 3 31  ? 121.934 139.519 75.900  1.00 42.94  ? 30  ASN c C   1 
ATOM 1956 O O   . ASN C 3 31  ? 121.373 138.476 76.256  1.00 42.94  ? 30  ASN c O   1 
ATOM 1957 C CB  . ASN C 3 31  ? 123.000 138.410 73.920  1.00 42.94  ? 30  ASN c CB  1 
ATOM 1958 C CG  . ASN C 3 31  ? 124.344 138.157 74.565  1.00 42.94  ? 30  ASN c CG  1 
ATOM 1959 O OD1 . ASN C 3 31  ? 125.107 139.086 74.821  1.00 42.94  ? 30  ASN c OD1 1 
ATOM 1960 N ND2 . ASN C 3 31  ? 124.652 136.891 74.809  1.00 42.94  ? 30  ASN c ND2 1 
ATOM 1961 N N   . GLY C 3 32  ? 122.203 140.504 76.753  1.00 41.00  ? 31  GLY c N   1 
ATOM 1962 C CA  . GLY C 3 32  ? 121.712 140.492 78.118  1.00 41.00  ? 31  GLY c CA  1 
ATOM 1963 C C   . GLY C 3 32  ? 122.228 139.367 78.989  1.00 41.00  ? 31  GLY c C   1 
ATOM 1964 O O   . GLY C 3 32  ? 121.449 138.720 79.694  1.00 41.00  ? 31  GLY c O   1 
ATOM 1965 N N   . VAL C 3 33  ? 123.534 139.124 78.959  1.00 37.89  ? 32  VAL c N   1 
ATOM 1966 C CA  . VAL C 3 33  ? 124.163 138.071 79.746  1.00 37.89  ? 32  VAL c CA  1 
ATOM 1967 C C   . VAL C 3 33  ? 124.949 138.720 80.874  1.00 37.89  ? 32  VAL c C   1 
ATOM 1968 O O   . VAL C 3 33  ? 125.905 139.464 80.626  1.00 37.89  ? 32  VAL c O   1 
ATOM 1969 C CB  . VAL C 3 33  ? 125.071 137.187 78.880  1.00 37.89  ? 32  VAL c CB  1 
ATOM 1970 C CG1 . VAL C 3 33  ? 125.956 136.328 79.751  1.00 37.89  ? 32  VAL c CG1 1 
ATOM 1971 C CG2 . VAL C 3 33  ? 124.233 136.319 77.970  1.00 37.89  ? 32  VAL c CG2 1 
ATOM 1972 N N   . ALA C 3 34  ? 124.550 138.441 82.111  1.00 35.57  ? 33  ALA c N   1 
ATOM 1973 C CA  . ALA C 3 34  ? 125.299 138.916 83.261  1.00 35.57  ? 33  ALA c CA  1 
ATOM 1974 C C   . ALA C 3 34  ? 126.631 138.181 83.360  1.00 35.57  ? 33  ALA c C   1 
ATOM 1975 O O   . ALA C 3 34  ? 126.851 137.154 82.717  1.00 35.57  ? 33  ALA c O   1 
ATOM 1976 C CB  . ALA C 3 34  ? 124.496 138.724 84.545  1.00 35.57  ? 33  ALA c CB  1 
ATOM 1977 N N   . SER C 3 35  ? 127.531 138.720 84.176  1.00 34.70  ? 34  SER c N   1 
ATOM 1978 C CA  . SER C 3 35  ? 128.846 138.122 84.334  1.00 34.70  ? 34  SER c CA  1 
ATOM 1979 C C   . SER C 3 35  ? 129.345 138.315 85.755  1.00 34.70  ? 34  SER c C   1 
ATOM 1980 O O   . SER C 3 35  ? 129.117 139.360 86.367  1.00 34.70  ? 34  SER c O   1 
ATOM 1981 C CB  . SER C 3 35  ? 129.851 138.720 83.346  1.00 34.70  ? 34  SER c CB  1 
ATOM 1982 O OG  . SER C 3 35  ? 129.387 138.601 82.015  1.00 34.70  ? 34  SER c OG  1 
ATOM 1983 N N   . LEU C 3 36  ? 130.026 137.297 86.270  1.00 32.08  ? 35  LEU c N   1 
ATOM 1984 C CA  . LEU C 3 36  ? 130.696 137.363 87.557  1.00 32.08  ? 35  LEU c CA  1 
ATOM 1985 C C   . LEU C 3 36  ? 132.043 136.672 87.428  1.00 32.08  ? 35  LEU c C   1 
ATOM 1986 O O   . LEU C 3 36  ? 132.207 135.757 86.619  1.00 32.08  ? 35  LEU c O   1 
ATOM 1987 C CB  . LEU C 3 36  ? 129.871 136.707 88.668  1.00 32.08  ? 35  LEU c CB  1 
ATOM 1988 C CG  . LEU C 3 36  ? 128.504 137.313 88.973  1.00 32.08  ? 35  LEU c CG  1 
ATOM 1989 C CD1 . LEU C 3 36  ? 127.419 136.508 88.292  1.00 32.08  ? 35  LEU c CD1 1 
ATOM 1990 C CD2 . LEU C 3 36  ? 128.267 137.360 90.467  1.00 32.08  ? 35  LEU c CD2 1 
ATOM 1991 N N   . SER C 3 37  ? 133.011 137.120 88.222  1.00 35.62  ? 36  SER c N   1 
ATOM 1992 C CA  . SER C 3 37  ? 134.345 136.545 88.166  1.00 35.62  ? 36  SER c CA  1 
ATOM 1993 C C   . SER C 3 37  ? 135.015 136.687 89.521  1.00 35.62  ? 36  SER c C   1 
ATOM 1994 O O   . SER C 3 37  ? 134.640 137.532 90.337  1.00 35.62  ? 36  SER c O   1 
ATOM 1995 C CB  . SER C 3 37  ? 135.205 137.208 87.085  1.00 35.62  ? 36  SER c CB  1 
ATOM 1996 O OG  . SER C 3 37  ? 134.487 137.359 85.875  1.00 35.62  ? 36  SER c OG  1 
ATOM 1997 N N   . GLN C 3 38  ? 136.018 135.850 89.747  1.00 39.84  ? 37  GLN c N   1 
ATOM 1998 C CA  . GLN C 3 38  ? 136.828 135.902 90.952  1.00 39.84  ? 37  GLN c CA  1 
ATOM 1999 C C   . GLN C 3 38  ? 138.083 136.723 90.692  1.00 39.84  ? 37  GLN c C   1 
ATOM 2000 O O   . GLN C 3 38  ? 138.628 136.720 89.586  1.00 39.84  ? 37  GLN c O   1 
ATOM 2001 C CB  . GLN C 3 38  ? 137.216 134.498 91.414  1.00 39.84  ? 37  GLN c CB  1 
ATOM 2002 C CG  . GLN C 3 38  ? 137.745 134.445 92.832  1.00 39.84  ? 37  GLN c CG  1 
ATOM 2003 C CD  . GLN C 3 38  ? 138.325 133.096 93.186  1.00 39.84  ? 37  GLN c CD  1 
ATOM 2004 O OE1 . GLN C 3 38  ? 138.501 132.239 92.324  1.00 39.84  ? 37  GLN c OE1 1 
ATOM 2005 N NE2 . GLN C 3 38  ? 138.625 132.899 94.463  1.00 39.84  ? 37  GLN c NE2 1 
ATOM 2006 N N   . ALA C 3 39  ? 138.542 137.424 91.725  1.00 43.56  ? 38  ALA c N   1 
ATOM 2007 C CA  . ALA C 3 39  ? 139.742 138.239 91.596  1.00 43.56  ? 38  ALA c CA  1 
ATOM 2008 C C   . ALA C 3 39  ? 140.977 137.353 91.530  1.00 43.56  ? 38  ALA c C   1 
ATOM 2009 O O   . ALA C 3 39  ? 141.527 136.966 92.565  1.00 43.56  ? 38  ALA c O   1 
ATOM 2010 C CB  . ALA C 3 39  ? 139.850 139.226 92.759  1.00 43.56  ? 38  ALA c CB  1 
ATOM 2011 N N   . GLY C 3 40  ? 141.417 137.023 90.315  1.00 46.81  ? 39  GLY c N   1 
ATOM 2012 C CA  . GLY C 3 40  ? 142.554 136.155 90.118  1.00 46.81  ? 39  GLY c CA  1 
ATOM 2013 C C   . GLY C 3 40  ? 143.845 136.925 89.875  1.00 46.81  ? 39  GLY c C   1 
ATOM 2014 O O   . GLY C 3 40  ? 143.867 138.147 89.762  1.00 46.81  ? 39  GLY c O   1 
ATOM 2015 N N   . ALA C 3 41  ? 144.940 136.165 89.800  1.00 48.53  ? 40  ALA c N   1 
ATOM 2016 C CA  . ALA C 3 41  ? 146.246 136.767 89.553  1.00 48.53  ? 40  ALA c CA  1 
ATOM 2017 C C   . ALA C 3 41  ? 146.323 137.359 88.152  1.00 48.53  ? 40  ALA c C   1 
ATOM 2018 O O   . ALA C 3 41  ? 146.781 138.492 87.969  1.00 48.53  ? 40  ALA c O   1 
ATOM 2019 C CB  . ALA C 3 41  ? 147.347 135.726 89.762  1.00 48.53  ? 40  ALA c CB  1 
ATOM 2020 N N   . VAL C 3 42  ? 145.874 136.607 87.153  1.00 46.83  ? 41  VAL c N   1 
ATOM 2021 C CA  . VAL C 3 42  ? 145.905 137.023 85.758  1.00 46.83  ? 41  VAL c CA  1 
ATOM 2022 C C   . VAL C 3 42  ? 144.478 136.965 85.233  1.00 46.83  ? 41  VAL c C   1 
ATOM 2023 O O   . VAL C 3 42  ? 143.786 135.973 85.467  1.00 46.83  ? 41  VAL c O   1 
ATOM 2024 C CB  . VAL C 3 42  ? 146.826 136.135 84.902  1.00 46.83  ? 41  VAL c CB  1 
ATOM 2025 C CG1 . VAL C 3 42  ? 146.851 136.617 83.466  1.00 46.83  ? 41  VAL c CG1 1 
ATOM 2026 C CG2 . VAL C 3 42  ? 148.226 136.112 85.484  1.00 46.83  ? 41  VAL c CG2 1 
ATOM 2027 N N   . PRO C 3 43  ? 143.992 137.995 84.537  1.00 43.72  ? 42  PRO c N   1 
ATOM 2028 C CA  . PRO C 3 43  ? 142.608 137.952 84.041  1.00 43.72  ? 42  PRO c CA  1 
ATOM 2029 C C   . PRO C 3 43  ? 142.335 136.808 83.084  1.00 43.72  ? 42  PRO c C   1 
ATOM 2030 O O   . PRO C 3 43  ? 141.181 136.380 82.960  1.00 43.72  ? 42  PRO c O   1 
ATOM 2031 C CB  . PRO C 3 43  ? 142.447 139.312 83.350  1.00 43.72  ? 42  PRO c CB  1 
ATOM 2032 C CG  . PRO C 3 43  ? 143.437 140.188 84.018  1.00 43.72  ? 42  PRO c CG  1 
ATOM 2033 C CD  . PRO C 3 43  ? 144.612 139.312 84.322  1.00 43.72  ? 42  PRO c CD  1 
ATOM 2034 N N   . ALA C 3 44  ? 143.358 136.299 82.398  1.00 44.50  ? 43  ALA c N   1 
ATOM 2035 C CA  . ALA C 3 44  ? 143.157 135.227 81.433  1.00 44.50  ? 43  ALA c CA  1 
ATOM 2036 C C   . ALA C 3 44  ? 142.800 133.900 82.083  1.00 44.50  ? 43  ALA c C   1 
ATOM 2037 O O   . ALA C 3 44  ? 142.314 133.004 81.387  1.00 44.50  ? 43  ALA c O   1 
ATOM 2038 C CB  . ALA C 3 44  ? 144.408 135.052 80.573  1.00 44.50  ? 43  ALA c CB  1 
ATOM 2039 N N   . LEU C 3 45  ? 143.031 133.745 83.385  1.00 46.09  ? 44  LEU c N   1 
ATOM 2040 C CA  . LEU C 3 45  ? 142.744 132.489 84.075  1.00 46.09  ? 44  LEU c CA  1 
ATOM 2041 C C   . LEU C 3 45  ? 142.077 132.826 85.406  1.00 46.09  ? 44  LEU c C   1 
ATOM 2042 O O   . LEU C 3 45  ? 142.725 133.301 86.341  1.00 46.09  ? 44  LEU c O   1 
ATOM 2043 C CB  . LEU C 3 45  ? 144.013 131.651 84.233  1.00 46.09  ? 44  LEU c CB  1 
ATOM 2044 C CG  . LEU C 3 45  ? 145.277 132.065 85.001  1.00 46.09  ? 44  LEU c CG  1 
ATOM 2045 C CD1 . LEU C 3 45  ? 145.225 131.739 86.489  1.00 46.09  ? 44  LEU c CD1 1 
ATOM 2046 C CD2 . LEU C 3 45  ? 146.512 131.465 84.357  1.00 46.09  ? 44  LEU c CD2 1 
ATOM 2047 N N   . GLU C 3 46  ? 140.764 132.626 85.460  1.00 43.65  ? 45  GLU c N   1 
ATOM 2048 C CA  . GLU C 3 46  ? 139.986 132.830 86.672  1.00 43.65  ? 45  GLU c CA  1 
ATOM 2049 C C   . GLU C 3 46  ? 138.618 132.204 86.459  1.00 43.65  ? 45  GLU c C   1 
ATOM 2050 O O   . GLU C 3 46  ? 138.205 131.941 85.328  1.00 43.65  ? 45  GLU c O   1 
ATOM 2051 C CB  . GLU C 3 46  ? 139.855 134.313 87.027  1.00 43.65  ? 45  GLU c CB  1 
ATOM 2052 C CG  . GLU C 3 46  ? 139.603 135.211 85.836  1.00 43.65  ? 45  GLU c CG  1 
ATOM 2053 C CD  . GLU C 3 46  ? 139.378 136.651 86.237  1.00 43.65  ? 45  GLU c CD  1 
ATOM 2054 O OE1 . GLU C 3 46  ? 140.080 137.129 87.151  1.00 43.65  ? 45  GLU c OE1 1 
ATOM 2055 O OE2 . GLU C 3 46  ? 138.498 137.306 85.640  1.00 43.65  ? 45  GLU c OE2 1 
ATOM 2056 N N   . LYS C 3 47  ? 137.918 131.974 87.563  1.00 37.47  ? 46  LYS c N   1 
ATOM 2057 C CA  . LYS C 3 47  ? 136.622 131.317 87.510  1.00 37.47  ? 46  LYS c CA  1 
ATOM 2058 C C   . LYS C 3 47  ? 135.540 132.325 87.153  1.00 37.47  ? 46  LYS c C   1 
ATOM 2059 O O   . LYS C 3 47  ? 135.449 133.394 87.764  1.00 37.47  ? 46  LYS c O   1 
ATOM 2060 C CB  . LYS C 3 47  ? 136.332 130.648 88.849  1.00 37.47  ? 46  LYS c CB  1 
ATOM 2061 C CG  . LYS C 3 47  ? 137.425 129.677 89.246  1.00 37.47  ? 46  LYS c CG  1 
ATOM 2062 C CD  . LYS C 3 47  ? 137.373 129.308 90.708  1.00 37.47  ? 46  LYS c CD  1 
ATOM 2063 C CE  . LYS C 3 47  ? 138.248 128.101 90.971  1.00 37.47  ? 46  LYS c CE  1 
ATOM 2064 N NZ  . LYS C 3 47  ? 139.557 128.213 90.278  1.00 37.47  ? 46  LYS c NZ  1 
ATOM 2065 N N   . ARG C 3 48  ? 134.721 131.985 86.160  1.00 36.23  ? 47  ARG c N   1 
ATOM 2066 C CA  . ARG C 3 48  ? 133.720 132.894 85.626  1.00 36.23  ? 47  ARG c CA  1 
ATOM 2067 C C   . ARG C 3 48  ? 132.345 132.249 85.680  1.00 36.23  ? 47  ARG c C   1 
ATOM 2068 O O   . ARG C 3 48  ? 132.207 131.033 85.544  1.00 36.23  ? 47  ARG c O   1 
ATOM 2069 C CB  . ARG C 3 48  ? 134.039 133.293 84.183  1.00 36.23  ? 47  ARG c CB  1 
ATOM 2070 C CG  . ARG C 3 48  ? 135.483 133.682 83.957  1.00 36.23  ? 47  ARG c CG  1 
ATOM 2071 C CD  . ARG C 3 48  ? 135.587 134.892 83.043  1.00 36.23  ? 47  ARG c CD  1 
ATOM 2072 N NE  . ARG C 3 48  ? 136.957 135.143 82.612  1.00 36.23  ? 47  ARG c NE  1 
ATOM 2073 C CZ  . ARG C 3 48  ? 137.629 134.385 81.757  1.00 36.23  ? 47  ARG c CZ  1 
ATOM 2074 N NH1 . ARG C 3 48  ? 137.084 133.315 81.203  1.00 36.23  ? 47  ARG c NH1 1 
ATOM 2075 N NH2 . ARG C 3 48  ? 138.879 134.713 81.443  1.00 36.23  ? 47  ARG c NH2 1 
ATOM 2076 N N   . VAL C 3 49  ? 131.327 133.081 85.889  1.00 31.54  ? 48  VAL c N   1 
ATOM 2077 C CA  . VAL C 3 49  ? 129.935 132.649 85.912  1.00 31.54  ? 48  VAL c CA  1 
ATOM 2078 C C   . VAL C 3 49  ? 129.108 133.657 85.131  1.00 31.54  ? 48  VAL c C   1 
ATOM 2079 O O   . VAL C 3 49  ? 129.299 134.869 85.271  1.00 31.54  ? 48  VAL c O   1 
ATOM 2080 C CB  . VAL C 3 49  ? 129.394 132.519 87.350  1.00 31.54  ? 48  VAL c CB  1 
ATOM 2081 C CG1 . VAL C 3 49  ? 127.981 131.989 87.328  1.00 31.54  ? 48  VAL c CG1 1 
ATOM 2082 C CG2 . VAL C 3 49  ? 130.288 131.631 88.188  1.00 31.54  ? 48  VAL c CG2 1 
ATOM 2083 N N   . THR C 3 50  ? 128.190 133.162 84.304  1.00 31.61  ? 49  THR c N   1 
ATOM 2084 C CA  . THR C 3 50  ? 127.281 134.013 83.548  1.00 31.61  ? 49  THR c CA  1 
ATOM 2085 C C   . THR C 3 50  ? 125.857 133.520 83.743  1.00 31.61  ? 49  THR c C   1 
ATOM 2086 O O   . THR C 3 50  ? 125.587 132.326 83.591  1.00 31.61  ? 49  THR c O   1 
ATOM 2087 C CB  . THR C 3 50  ? 127.621 134.024 82.054  1.00 31.61  ? 49  THR c CB  1 
ATOM 2088 O OG1 . THR C 3 50  ? 127.307 132.750 81.482  1.00 31.61  ? 49  THR c OG1 1 
ATOM 2089 C CG2 . THR C 3 50  ? 129.095 134.322 81.835  1.00 31.61  ? 49  THR c CG2 1 
ATOM 2090 N N   . VAL C 3 51  ? 124.949 134.436 84.069  1.00 31.51  ? 50  VAL c N   1 
ATOM 2091 C CA  . VAL C 3 51  ? 123.534 134.129 84.245  1.00 31.51  ? 50  VAL c CA  1 
ATOM 2092 C C   . VAL C 3 51  ? 122.742 134.905 83.205  1.00 31.51  ? 50  VAL c C   1 
ATOM 2093 O O   . VAL C 3 51  ? 122.863 136.132 83.114  1.00 31.51  ? 50  VAL c O   1 
ATOM 2094 C CB  . VAL C 3 51  ? 123.054 134.470 85.664  1.00 31.51  ? 50  VAL c CB  1 
ATOM 2095 C CG1 . VAL C 3 51  ? 121.561 134.242 85.780  1.00 31.51  ? 50  VAL c CG1 1 
ATOM 2096 C CG2 . VAL C 3 51  ? 123.799 133.638 86.687  1.00 31.51  ? 50  VAL c CG2 1 
ATOM 2097 N N   . SER C 3 52  ? 121.928 134.197 82.428  1.00 35.42  ? 51  SER c N   1 
ATOM 2098 C CA  . SER C 3 52  ? 121.131 134.808 81.374  1.00 35.42  ? 51  SER c CA  1 
ATOM 2099 C C   . SER C 3 52  ? 119.671 134.429 81.552  1.00 35.42  ? 51  SER c C   1 
ATOM 2100 O O   . SER C 3 52  ? 119.340 133.244 81.637  1.00 35.42  ? 51  SER c O   1 
ATOM 2101 C CB  . SER C 3 52  ? 121.621 134.375 79.992  1.00 35.42  ? 51  SER c CB  1 
ATOM 2102 O OG  . SER C 3 52  ? 120.663 134.684 78.998  1.00 35.42  ? 51  SER c OG  1 
ATOM 2103 N N   . VAL C 3 53  ? 118.802 135.434 81.592  1.00 41.04  ? 52  VAL c N   1 
ATOM 2104 C CA  . VAL C 3 53  ? 117.362 135.239 81.702  1.00 41.04  ? 52  VAL c CA  1 
ATOM 2105 C C   . VAL C 3 53  ? 116.700 135.952 80.534  1.00 41.04  ? 52  VAL c C   1 
ATOM 2106 O O   . VAL C 3 53  ? 117.004 137.119 80.263  1.00 41.04  ? 52  VAL c O   1 
ATOM 2107 C CB  . VAL C 3 53  ? 116.816 135.764 83.041  1.00 41.04  ? 52  VAL c CB  1 
ATOM 2108 C CG1 . VAL C 3 53  ? 115.302 135.751 83.031  1.00 41.04  ? 52  VAL c CG1 1 
ATOM 2109 C CG2 . VAL C 3 53  ? 117.347 134.932 84.190  1.00 41.04  ? 52  VAL c CG2 1 
ATOM 2110 N N   . SER C 3 54  ? 115.810 135.249 79.838  1.00 49.94  ? 53  SER c N   1 
ATOM 2111 C CA  . SER C 3 54  ? 115.095 135.856 78.725  1.00 49.94  ? 53  SER c CA  1 
ATOM 2112 C C   . SER C 3 54  ? 114.234 137.010 79.224  1.00 49.94  ? 53  SER c C   1 
ATOM 2113 O O   . SER C 3 54  ? 113.513 136.878 80.217  1.00 49.94  ? 53  SER c O   1 
ATOM 2114 C CB  . SER C 3 54  ? 114.236 134.812 78.016  1.00 49.94  ? 53  SER c CB  1 
ATOM 2115 O OG  . SER C 3 54  ? 113.000 134.640 78.681  1.00 49.94  ? 53  SER c OG  1 
ATOM 2116 N N   . GLN C 3 55  ? 114.318 138.143 78.532  1.00 59.36  ? 54  GLN c N   1 
ATOM 2117 C CA  . GLN C 3 55  ? 113.642 139.349 78.982  1.00 59.36  ? 54  GLN c CA  1 
ATOM 2118 C C   . GLN C 3 55  ? 112.127 139.202 78.852  1.00 59.36  ? 54  GLN c C   1 
ATOM 2119 O O   . GLN C 3 55  ? 111.636 138.533 77.939  1.00 59.36  ? 54  GLN c O   1 
ATOM 2120 C CB  . GLN C 3 55  ? 114.111 140.555 78.174  1.00 59.36  ? 54  GLN c CB  1 
ATOM 2121 C CG  . GLN C 3 55  ? 115.617 140.745 78.154  1.00 59.36  ? 54  GLN c CG  1 
ATOM 2122 C CD  . GLN C 3 55  ? 116.147 141.310 79.454  1.00 59.36  ? 54  GLN c CD  1 
ATOM 2123 O OE1 . GLN C 3 55  ? 115.423 141.973 80.197  1.00 59.36  ? 54  GLN c OE1 1 
ATOM 2124 N NE2 . GLN C 3 55  ? 117.418 141.052 79.736  1.00 59.36  ? 54  GLN c NE2 1 
ATOM 2125 N N   . PRO C 3 56  ? 111.366 139.812 79.759  1.00 67.33  ? 55  PRO c N   1 
ATOM 2126 C CA  . PRO C 3 56  ? 109.906 139.793 79.622  1.00 67.33  ? 55  PRO c CA  1 
ATOM 2127 C C   . PRO C 3 56  ? 109.465 140.559 78.386  1.00 67.33  ? 55  PRO c C   1 
ATOM 2128 O O   . PRO C 3 56  ? 110.050 141.582 78.025  1.00 67.33  ? 55  PRO c O   1 
ATOM 2129 C CB  . PRO C 3 56  ? 109.420 140.471 80.906  1.00 67.33  ? 55  PRO c CB  1 
ATOM 2130 C CG  . PRO C 3 56  ? 110.551 141.344 81.314  1.00 67.33  ? 55  PRO c CG  1 
ATOM 2131 C CD  . PRO C 3 56  ? 111.800 140.605 80.921  1.00 67.33  ? 55  PRO c CD  1 
ATOM 2132 N N   . SER C 3 57  ? 108.416 140.056 77.742  1.00 72.99  ? 56  SER c N   1 
ATOM 2133 C CA  . SER C 3 57  ? 107.882 140.672 76.537  1.00 72.99  ? 56  SER c CA  1 
ATOM 2134 C C   . SER C 3 57  ? 106.363 140.556 76.578  1.00 72.99  ? 56  SER c C   1 
ATOM 2135 O O   . SER C 3 57  ? 105.780 140.131 77.580  1.00 72.99  ? 56  SER c O   1 
ATOM 2136 C CB  . SER C 3 57  ? 108.485 140.030 75.281  1.00 72.99  ? 56  SER c CB  1 
ATOM 2137 O OG  . SER C 3 57  ? 107.944 140.604 74.105  1.00 72.99  ? 56  SER c OG  1 
ATOM 2138 N N   . ARG C 3 58  ? 105.718 140.943 75.476  1.00 76.89  ? 57  ARG c N   1 
ATOM 2139 C CA  . ARG C 3 58  ? 104.259 140.955 75.442  1.00 76.89  ? 57  ARG c CA  1 
ATOM 2140 C C   . ARG C 3 58  ? 103.690 139.545 75.535  1.00 76.89  ? 57  ARG c C   1 
ATOM 2141 O O   . ARG C 3 58  ? 102.828 139.268 76.377  1.00 76.89  ? 57  ARG c O   1 
ATOM 2142 C CB  . ARG C 3 58  ? 103.771 141.651 74.170  1.00 76.89  ? 57  ARG c CB  1 
ATOM 2143 C CG  . ARG C 3 58  ? 103.713 143.172 74.264  1.00 76.89  ? 57  ARG c CG  1 
ATOM 2144 C CD  . ARG C 3 58  ? 105.085 143.797 74.058  1.00 76.89  ? 57  ARG c CD  1 
ATOM 2145 N NE  . ARG C 3 58  ? 105.054 145.250 74.177  1.00 76.89  ? 57  ARG c NE  1 
ATOM 2146 C CZ  . ARG C 3 58  ? 104.822 146.079 73.168  1.00 76.89  ? 57  ARG c CZ  1 
ATOM 2147 N NH1 . ARG C 3 58  ? 104.592 145.632 71.944  1.00 76.89  ? 57  ARG c NH1 1 
ATOM 2148 N NH2 . ARG C 3 58  ? 104.824 147.390 73.393  1.00 76.89  ? 57  ARG c NH2 1 
ATOM 2149 N N   . ASN C 3 59  ? 104.161 138.634 74.681  1.00 74.21  ? 58  ASN c N   1 
ATOM 2150 C CA  . ASN C 3 59  ? 103.650 137.267 74.671  1.00 74.21  ? 58  ASN c CA  1 
ATOM 2151 C C   . ASN C 3 59  ? 104.710 136.240 75.041  1.00 74.21  ? 58  ASN c C   1 
ATOM 2152 O O   . ASN C 3 59  ? 104.529 135.507 76.019  1.00 74.21  ? 58  ASN c O   1 
ATOM 2153 C CB  . ASN C 3 59  ? 103.062 136.947 73.291  1.00 74.21  ? 58  ASN c CB  1 
ATOM 2154 C CG  . ASN C 3 59  ? 101.998 137.935 72.869  1.00 74.21  ? 58  ASN c CG  1 
ATOM 2155 O OD1 . ASN C 3 59  ? 102.197 138.723 71.944  1.00 74.21  ? 58  ASN c OD1 1 
ATOM 2156 N ND2 . ASN C 3 59  ? 100.855 137.897 73.543  1.00 74.21  ? 58  ASN c ND2 1 
ATOM 2157 N N   . ARG C 3 60  ? 105.811 136.169 74.287  1.00 64.25  ? 59  ARG c N   1 
ATOM 2158 C CA  . ARG C 3 60  ? 106.857 135.160 74.444  1.00 64.25  ? 59  ARG c CA  1 
ATOM 2159 C C   . ARG C 3 60  ? 106.332 133.750 74.186  1.00 64.25  ? 59  ARG c C   1 
ATOM 2160 O O   . ARG C 3 60  ? 105.136 133.480 74.341  1.00 64.25  ? 59  ARG c O   1 
ATOM 2161 C CB  . ARG C 3 60  ? 107.497 135.233 75.834  1.00 64.25  ? 59  ARG c CB  1 
ATOM 2162 C CG  . ARG C 3 60  ? 108.262 136.510 76.098  1.00 64.25  ? 59  ARG c CG  1 
ATOM 2163 C CD  . ARG C 3 60  ? 109.395 136.272 77.077  1.00 64.25  ? 59  ARG c CD  1 
ATOM 2164 N NE  . ARG C 3 60  ? 110.484 135.506 76.486  1.00 64.25  ? 59  ARG c NE  1 
ATOM 2165 C CZ  . ARG C 3 60  ? 111.357 135.993 75.615  1.00 64.25  ? 59  ARG c CZ  1 
ATOM 2166 N NH1 . ARG C 3 60  ? 111.313 137.256 75.226  1.00 64.25  ? 59  ARG c NH1 1 
ATOM 2167 N NH2 . ARG C 3 60  ? 112.301 135.194 75.128  1.00 64.25  ? 59  ARG c NH2 1 
ATOM 2168 N N   . LYS C 3 61  ? 107.221 132.841 73.789  1.00 60.91  ? 60  LYS c N   1 
ATOM 2169 C CA  . LYS C 3 61  ? 106.842 131.435 73.694  1.00 60.91  ? 60  LYS c CA  1 
ATOM 2170 C C   . LYS C 3 61  ? 106.954 130.762 75.056  1.00 60.91  ? 60  LYS c C   1 
ATOM 2171 O O   . LYS C 3 61  ? 105.958 130.303 75.624  1.00 60.91  ? 60  LYS c O   1 
ATOM 2172 C CB  . LYS C 3 61  ? 107.721 130.723 72.663  1.00 60.91  ? 60  LYS c CB  1 
ATOM 2173 C CG  . LYS C 3 61  ? 107.667 131.330 71.272  1.00 60.91  ? 60  LYS c CG  1 
ATOM 2174 C CD  . LYS C 3 61  ? 108.592 130.594 70.318  1.00 60.91  ? 60  LYS c CD  1 
ATOM 2175 C CE  . LYS C 3 61  ? 110.049 130.810 70.690  1.00 60.91  ? 60  LYS c CE  1 
ATOM 2176 N NZ  . LYS C 3 61  ? 110.462 132.230 70.517  1.00 60.91  ? 60  LYS c NZ  1 
ATOM 2177 N N   . ASN C 3 62  ? 108.167 130.714 75.596  1.00 51.01  ? 61  ASN c N   1 
ATOM 2178 C CA  . ASN C 3 62  ? 108.411 130.249 76.952  1.00 51.01  ? 61  ASN c CA  1 
ATOM 2179 C C   . ASN C 3 62  ? 109.743 130.816 77.414  1.00 51.01  ? 61  ASN c C   1 
ATOM 2180 O O   . ASN C 3 62  ? 110.590 131.197 76.602  1.00 51.01  ? 61  ASN c O   1 
ATOM 2181 C CB  . ASN C 3 62  ? 108.362 128.716 77.043  1.00 51.01  ? 61  ASN c CB  1 
ATOM 2182 C CG  . ASN C 3 62  ? 109.447 128.029 76.228  1.00 51.01  ? 61  ASN c CG  1 
ATOM 2183 O OD1 . ASN C 3 62  ? 110.336 128.667 75.668  1.00 51.01  ? 61  ASN c OD1 1 
ATOM 2184 N ND2 . ASN C 3 62  ? 109.369 126.706 76.160  1.00 51.01  ? 61  ASN c ND2 1 
ATOM 2185 N N   . TYR C 3 63  ? 109.910 130.889 78.726  1.00 45.96  ? 62  TYR c N   1 
ATOM 2186 C CA  . TYR C 3 63  ? 111.066 131.558 79.295  1.00 45.96  ? 62  TYR c CA  1 
ATOM 2187 C C   . TYR C 3 63  ? 112.261 130.614 79.371  1.00 45.96  ? 62  TYR c C   1 
ATOM 2188 O O   . TYR C 3 63  ? 112.153 129.407 79.154  1.00 45.96  ? 62  TYR c O   1 
ATOM 2189 C CB  . TYR C 3 63  ? 110.727 132.116 80.672  1.00 45.96  ? 62  TYR c CB  1 
ATOM 2190 C CG  . TYR C 3 63  ? 109.725 133.241 80.621  1.00 45.96  ? 62  TYR c CG  1 
ATOM 2191 C CD1 . TYR C 3 63  ? 108.366 132.989 80.703  1.00 45.96  ? 62  TYR c CD1 1 
ATOM 2192 C CD2 . TYR C 3 63  ? 110.139 134.556 80.486  1.00 45.96  ? 62  TYR c CD2 1 
ATOM 2193 C CE1 . TYR C 3 63  ? 107.448 134.015 80.656  1.00 45.96  ? 62  TYR c CE1 1 
ATOM 2194 C CE2 . TYR C 3 63  ? 109.229 135.589 80.442  1.00 45.96  ? 62  TYR c CE2 1 
ATOM 2195 C CZ  . TYR C 3 63  ? 107.885 135.314 80.525  1.00 45.96  ? 62  TYR c CZ  1 
ATOM 2196 O OH  . TYR C 3 63  ? 106.974 136.343 80.477  1.00 45.96  ? 62  TYR c OH  1 
ATOM 2197 N N   . LYS C 3 64  ? 113.419 131.189 79.683  1.00 39.00  ? 63  LYS c N   1 
ATOM 2198 C CA  . LYS C 3 64  ? 114.664 130.438 79.716  1.00 39.00  ? 63  LYS c CA  1 
ATOM 2199 C C   . LYS C 3 64  ? 115.600 131.068 80.733  1.00 39.00  ? 63  LYS c C   1 
ATOM 2200 O O   . LYS C 3 64  ? 115.781 132.288 80.739  1.00 39.00  ? 63  LYS c O   1 
ATOM 2201 C CB  . LYS C 3 64  ? 115.329 130.416 78.339  1.00 39.00  ? 63  LYS c CB  1 
ATOM 2202 C CG  . LYS C 3 64  ? 115.007 129.193 77.512  1.00 39.00  ? 63  LYS c CG  1 
ATOM 2203 C CD  . LYS C 3 64  ? 115.807 129.192 76.225  1.00 39.00  ? 63  LYS c CD  1 
ATOM 2204 C CE  . LYS C 3 64  ? 117.299 129.200 76.514  1.00 39.00  ? 63  LYS c CE  1 
ATOM 2205 N NZ  . LYS C 3 64  ? 118.111 129.183 75.267  1.00 39.00  ? 63  LYS c NZ  1 
ATOM 2206 N N   . VAL C 3 65  ? 116.188 130.235 81.583  1.00 31.77  ? 64  VAL c N   1 
ATOM 2207 C CA  . VAL C 3 65  ? 117.224 130.646 82.520  1.00 31.77  ? 64  VAL c CA  1 
ATOM 2208 C C   . VAL C 3 65  ? 118.438 129.769 82.265  1.00 31.77  ? 64  VAL c C   1 
ATOM 2209 O O   . VAL C 3 65  ? 118.321 128.540 82.239  1.00 31.77  ? 64  VAL c O   1 
ATOM 2210 C CB  . VAL C 3 65  ? 116.755 130.525 83.979  1.00 31.77  ? 64  VAL c CB  1 
ATOM 2211 C CG1 . VAL C 3 65  ? 117.902 130.799 84.928  1.00 31.77  ? 64  VAL c CG1 1 
ATOM 2212 C CG2 . VAL C 3 65  ? 115.600 131.466 84.241  1.00 31.77  ? 64  VAL c CG2 1 
ATOM 2213 N N   . GLN C 3 66  ? 119.596 130.392 82.070  1.00 31.17  ? 65  GLN c N   1 
ATOM 2214 C CA  . GLN C 3 66  ? 120.807 129.666 81.709  1.00 31.17  ? 65  GLN c CA  1 
ATOM 2215 C C   . GLN C 3 66  ? 121.960 130.131 82.583  1.00 31.17  ? 65  GLN c C   1 
ATOM 2216 O O   . GLN C 3 66  ? 122.309 131.315 82.576  1.00 31.17  ? 65  GLN c O   1 
ATOM 2217 C CB  . GLN C 3 66  ? 121.137 129.865 80.230  1.00 31.17  ? 65  GLN c CB  1 
ATOM 2218 C CG  . GLN C 3 66  ? 122.429 129.213 79.801  1.00 31.17  ? 65  GLN c CG  1 
ATOM 2219 C CD  . GLN C 3 66  ? 122.399 128.774 78.355  1.00 31.17  ? 65  GLN c CD  1 
ATOM 2220 O OE1 . GLN C 3 66  ? 121.618 129.288 77.555  1.00 31.17  ? 65  GLN c OE1 1 
ATOM 2221 N NE2 . GLN C 3 66  ? 123.251 127.816 78.010  1.00 31.17  ? 65  GLN c NE2 1 
ATOM 2222 N N   . VAL C 3 67  ? 122.549 129.200 83.325  1.00 27.87  ? 66  VAL c N   1 
ATOM 2223 C CA  . VAL C 3 67  ? 123.723 129.452 84.150  1.00 27.87  ? 66  VAL c CA  1 
ATOM 2224 C C   . VAL C 3 67  ? 124.877 128.659 83.562  1.00 27.87  ? 66  VAL c C   1 
ATOM 2225 O O   . VAL C 3 67  ? 124.697 127.513 83.140  1.00 27.87  ? 66  VAL c O   1 
ATOM 2226 C CB  . VAL C 3 67  ? 123.472 129.062 85.618  1.00 27.87  ? 66  VAL c CB  1 
ATOM 2227 C CG1 . VAL C 3 67  ? 124.731 129.233 86.446  1.00 27.87  ? 66  VAL c CG1 1 
ATOM 2228 C CG2 . VAL C 3 67  ? 122.339 129.880 86.185  1.00 27.87  ? 66  VAL c CG2 1 
ATOM 2229 N N   . LYS C 3 68  ? 126.059 129.267 83.524  1.00 29.05  ? 67  LYS c N   1 
ATOM 2230 C CA  . LYS C 3 68  ? 127.181 128.687 82.792  1.00 29.05  ? 67  LYS c CA  1 
ATOM 2231 C C   . LYS C 3 68  ? 128.470 129.045 83.514  1.00 29.05  ? 67  LYS c C   1 
ATOM 2232 O O   . LYS C 3 68  ? 128.875 130.210 83.511  1.00 29.05  ? 67  LYS c O   1 
ATOM 2233 C CB  . LYS C 3 68  ? 127.193 129.200 81.357  1.00 29.05  ? 67  LYS c CB  1 
ATOM 2234 C CG  . LYS C 3 68  ? 128.112 128.458 80.424  1.00 29.05  ? 67  LYS c CG  1 
ATOM 2235 C CD  . LYS C 3 68  ? 127.984 129.004 79.015  1.00 29.05  ? 67  LYS c CD  1 
ATOM 2236 C CE  . LYS C 3 68  ? 126.527 129.186 78.627  1.00 29.05  ? 67  LYS c CE  1 
ATOM 2237 N NZ  . LYS C 3 68  ? 126.345 129.161 77.153  1.00 29.05  ? 67  LYS c NZ  1 
ATOM 2238 N N   . ILE C 3 69  ? 129.116 128.053 84.121  1.00 29.12  ? 68  ILE c N   1 
ATOM 2239 C CA  . ILE C 3 69  ? 130.341 128.276 84.875  1.00 29.12  ? 68  ILE c CA  1 
ATOM 2240 C C   . ILE C 3 69  ? 131.486 127.552 84.184  1.00 29.12  ? 68  ILE c C   1 
ATOM 2241 O O   . ILE C 3 69  ? 131.292 126.587 83.442  1.00 29.12  ? 68  ILE c O   1 
ATOM 2242 C CB  . ILE C 3 69  ? 130.216 127.814 86.340  1.00 29.12  ? 68  ILE c CB  1 
ATOM 2243 C CG1 . ILE C 3 69  ? 129.963 126.316 86.410  1.00 29.12  ? 68  ILE c CG1 1 
ATOM 2244 C CG2 . ILE C 3 69  ? 129.056 128.496 87.011  1.00 29.12  ? 68  ILE c CG2 1 
ATOM 2245 C CD1 . ILE C 3 69  ? 130.062 125.768 87.808  1.00 29.12  ? 68  ILE c CD1 1 
ATOM 2246 N N   . GLN C 3 70  ? 132.701 128.035 84.434  1.00 33.99  ? 69  GLN c N   1 
ATOM 2247 C CA  . GLN C 3 70  ? 133.904 127.404 83.907  1.00 33.99  ? 69  GLN c CA  1 
ATOM 2248 C C   . GLN C 3 70  ? 135.082 127.757 84.802  1.00 33.99  ? 69  GLN c C   1 
ATOM 2249 O O   . GLN C 3 70  ? 135.224 128.909 85.220  1.00 33.99  ? 69  GLN c O   1 
ATOM 2250 C CB  . GLN C 3 70  ? 134.165 127.832 82.457  1.00 33.99  ? 69  GLN c CB  1 
ATOM 2251 C CG  . GLN C 3 70  ? 134.639 129.256 82.272  1.00 33.99  ? 69  GLN c CG  1 
ATOM 2252 C CD  . GLN C 3 70  ? 135.256 129.482 80.909  1.00 33.99  ? 69  GLN c CD  1 
ATOM 2253 O OE1 . GLN C 3 70  ? 135.116 128.656 80.011  1.00 33.99  ? 69  GLN c OE1 1 
ATOM 2254 N NE2 . GLN C 3 70  ? 135.945 130.604 80.749  1.00 33.99  ? 69  GLN c NE2 1 
ATOM 2255 N N   . ASN C 3 71  ? 135.902 126.761 85.117  1.00 37.19  ? 70  ASN c N   1 
ATOM 2256 C CA  . ASN C 3 71  ? 137.056 126.945 85.996  1.00 37.19  ? 70  ASN c CA  1 
ATOM 2257 C C   . ASN C 3 71  ? 138.325 126.499 85.292  1.00 37.19  ? 70  ASN c C   1 
ATOM 2258 O O   . ASN C 3 71  ? 138.544 125.283 85.130  1.00 37.19  ? 70  ASN c O   1 
ATOM 2259 C CB  . ASN C 3 71  ? 136.875 126.169 87.299  1.00 37.19  ? 70  ASN c CB  1 
ATOM 2260 C CG  . ASN C 3 71  ? 135.524 126.400 87.931  1.00 37.19  ? 70  ASN c CG  1 
ATOM 2261 O OD1 . ASN C 3 71  ? 134.880 125.465 88.401  1.00 37.19  ? 70  ASN c OD1 1 
ATOM 2262 N ND2 . ASN C 3 71  ? 135.087 127.650 87.952  1.00 37.19  ? 70  ASN c ND2 1 
ATOM 2263 N N   . PRO C 3 72  ? 139.189 127.416 84.863  1.00 44.53  ? 71  PRO c N   1 
ATOM 2264 C CA  . PRO C 3 72  ? 140.415 127.014 84.168  1.00 44.53  ? 71  PRO c CA  1 
ATOM 2265 C C   . PRO C 3 72  ? 141.573 126.753 85.117  1.00 44.53  ? 71  PRO c C   1 
ATOM 2266 O O   . PRO C 3 72  ? 141.825 127.501 86.062  1.00 44.53  ? 71  PRO c O   1 
ATOM 2267 C CB  . PRO C 3 72  ? 140.704 128.226 83.274  1.00 44.53  ? 71  PRO c CB  1 
ATOM 2268 C CG  . PRO C 3 72  ? 140.156 129.381 84.037  1.00 44.53  ? 71  PRO c CG  1 
ATOM 2269 C CD  . PRO C 3 72  ? 139.030 128.878 84.903  1.00 44.53  ? 71  PRO c CD  1 
ATOM 2270 N N   . THR C 3 73  ? 142.285 125.661 84.848  1.00 50.88  ? 72  THR c N   1 
ATOM 2271 C CA  . THR C 3 73  ? 143.488 125.292 85.578  1.00 50.88  ? 72  THR c CA  1 
ATOM 2272 C C   . THR C 3 73  ? 144.680 125.408 84.641  1.00 50.88  ? 72  THR c C   1 
ATOM 2273 O O   . THR C 3 73  ? 144.666 124.856 83.532  1.00 50.88  ? 72  THR c O   1 
ATOM 2274 C CB  . THR C 3 73  ? 143.399 123.872 86.137  1.00 50.88  ? 72  THR c CB  1 
ATOM 2275 O OG1 . THR C 3 73  ? 143.446 122.932 85.060  1.00 50.88  ? 72  THR c OG1 1 
ATOM 2276 C CG2 . THR C 3 73  ? 142.104 123.686 86.909  1.00 50.88  ? 72  THR c CG2 1 
ATOM 2277 N N   . ALA C 3 74  ? 145.707 126.120 85.098  1.00 58.54  ? 73  ALA c N   1 
ATOM 2278 C CA  . ALA C 3 74  ? 146.880 126.434 84.303  1.00 58.54  ? 73  ALA c CA  1 
ATOM 2279 C C   . ALA C 3 74  ? 148.145 126.044 85.054  1.00 58.54  ? 73  ALA c C   1 
ATOM 2280 O O   . ALA C 3 74  ? 148.160 125.945 86.283  1.00 58.54  ? 73  ALA c O   1 
ATOM 2281 C CB  . ALA C 3 74  ? 146.925 127.924 83.955  1.00 58.54  ? 73  ALA c CB  1 
ATOM 2282 N N   . CYS C 3 75  ? 149.214 125.828 84.292  1.00 69.93  ? 74  CYS c N   1 
ATOM 2283 C CA  . CYS C 3 75  ? 150.508 125.474 84.852  1.00 69.93  ? 74  CYS c CA  1 
ATOM 2284 C C   . CYS C 3 75  ? 151.586 126.308 84.178  1.00 69.93  ? 74  CYS c C   1 
ATOM 2285 O O   . CYS C 3 75  ? 151.444 126.735 83.030  1.00 69.93  ? 74  CYS c O   1 
ATOM 2286 C CB  . CYS C 3 75  ? 150.811 123.981 84.680  1.00 69.93  ? 74  CYS c CB  1 
ATOM 2287 S SG  . CYS C 3 75  ? 151.130 123.479 82.973  1.00 69.93  ? 74  CYS c SG  1 
ATOM 2288 N N   . THR C 3 76  ? 152.676 126.530 84.910  1.00 79.29  ? 75  THR c N   1 
ATOM 2289 C CA  . THR C 3 76  ? 153.813 127.303 84.409  1.00 79.29  ? 75  THR c CA  1 
ATOM 2290 C C   . THR C 3 76  ? 154.706 126.363 83.612  1.00 79.29  ? 75  THR c C   1 
ATOM 2291 O O   . THR C 3 76  ? 155.559 125.663 84.161  1.00 79.29  ? 75  THR c O   1 
ATOM 2292 C CB  . THR C 3 76  ? 154.570 127.959 85.556  1.00 79.29  ? 75  THR c CB  1 
ATOM 2293 O OG1 . THR C 3 76  ? 154.823 126.988 86.579  1.00 79.29  ? 75  THR c OG1 1 
ATOM 2294 C CG2 . THR C 3 76  ? 153.758 129.103 86.142  1.00 79.29  ? 75  THR c CG2 1 
ATOM 2295 N N   . ALA C 3 77  ? 154.503 126.344 82.299  1.00 86.07  ? 76  ALA c N   1 
ATOM 2296 C CA  . ALA C 3 77  ? 155.287 125.478 81.432  1.00 86.07  ? 76  ALA c CA  1 
ATOM 2297 C C   . ALA C 3 77  ? 156.736 125.945 81.374  1.00 86.07  ? 76  ALA c C   1 
ATOM 2298 O O   . ALA C 3 77  ? 157.032 127.138 81.464  1.00 86.07  ? 76  ALA c O   1 
ATOM 2299 C CB  . ALA C 3 77  ? 154.691 125.447 80.026  1.00 86.07  ? 76  ALA c CB  1 
ATOM 2300 N N   . ASN C 3 78  ? 157.643 124.983 81.233  1.00 94.19  ? 77  ASN c N   1 
ATOM 2301 C CA  . ASN C 3 78  ? 159.058 125.307 81.126  1.00 94.19  ? 77  ASN c CA  1 
ATOM 2302 C C   . ASN C 3 78  ? 159.328 126.081 79.842  1.00 94.19  ? 77  ASN c C   1 
ATOM 2303 O O   . ASN C 3 78  ? 158.707 125.834 78.805  1.00 94.19  ? 77  ASN c O   1 
ATOM 2304 C CB  . ASN C 3 78  ? 159.903 124.032 81.171  1.00 94.19  ? 77  ASN c CB  1 
ATOM 2305 C CG  . ASN C 3 78  ? 159.638 123.109 79.996  1.00 94.19  ? 77  ASN c CG  1 
ATOM 2306 O OD1 . ASN C 3 78  ? 160.111 123.346 78.884  1.00 94.19  ? 77  ASN c OD1 1 
ATOM 2307 N ND2 . ASN C 3 78  ? 158.881 122.045 80.239  1.00 94.19  ? 77  ASN c ND2 1 
ATOM 2308 N N   . GLY C 3 79  ? 160.257 127.030 79.920  1.00 94.30  ? 78  GLY c N   1 
ATOM 2309 C CA  . GLY C 3 79  ? 160.572 127.868 78.783  1.00 94.30  ? 78  GLY c CA  1 
ATOM 2310 C C   . GLY C 3 79  ? 159.621 129.019 78.553  1.00 94.30  ? 78  GLY c C   1 
ATOM 2311 O O   . GLY C 3 79  ? 159.702 129.667 77.503  1.00 94.30  ? 78  GLY c O   1 
ATOM 2312 N N   . SER C 3 80  ? 158.721 129.294 79.494  1.00 91.34  ? 79  SER c N   1 
ATOM 2313 C CA  . SER C 3 80  ? 157.781 130.397 79.373  1.00 91.34  ? 79  SER c CA  1 
ATOM 2314 C C   . SER C 3 80  ? 157.741 131.163 80.686  1.00 91.34  ? 79  SER c C   1 
ATOM 2315 O O   . SER C 3 80  ? 157.994 130.604 81.757  1.00 91.34  ? 79  SER c O   1 
ATOM 2316 C CB  . SER C 3 80  ? 156.375 129.908 79.004  1.00 91.34  ? 79  SER c CB  1 
ATOM 2317 O OG  . SER C 3 80  ? 156.402 129.124 77.824  1.00 91.34  ? 79  SER c OG  1 
ATOM 2318 N N   . CYS C 3 81  ? 157.416 132.452 80.591  1.00 88.81  ? 80  CYS c N   1 
ATOM 2319 C CA  . CYS C 3 81  ? 157.379 133.331 81.750  1.00 88.81  ? 80  CYS c CA  1 
ATOM 2320 C C   . CYS C 3 81  ? 155.970 133.647 82.230  1.00 88.81  ? 80  CYS c C   1 
ATOM 2321 O O   . CYS C 3 81  ? 155.821 134.234 83.307  1.00 88.81  ? 80  CYS c O   1 
ATOM 2322 C CB  . CYS C 3 81  ? 158.110 134.646 81.442  1.00 88.81  ? 80  CYS c CB  1 
ATOM 2323 S SG  . CYS C 3 81  ? 159.885 134.465 81.153  1.00 88.81  ? 80  CYS c SG  1 
ATOM 2324 N N   . ASP C 3 82  ? 154.940 133.280 81.471  1.00 82.74  ? 81  ASP c N   1 
ATOM 2325 C CA  . ASP C 3 82  ? 153.575 133.576 81.859  1.00 82.74  ? 81  ASP c CA  1 
ATOM 2326 C C   . ASP C 3 82  ? 152.737 132.304 81.880  1.00 82.74  ? 81  ASP c C   1 
ATOM 2327 O O   . ASP C 3 82  ? 152.911 131.434 81.020  1.00 82.74  ? 81  ASP c O   1 
ATOM 2328 C CB  . ASP C 3 82  ? 152.938 134.591 80.900  1.00 82.74  ? 81  ASP c CB  1 
ATOM 2329 C CG  . ASP C 3 82  ? 153.138 134.221 79.444  1.00 82.74  ? 81  ASP c CG  1 
ATOM 2330 O OD1 . ASP C 3 82  ? 153.955 133.320 79.164  1.00 82.74  ? 81  ASP c OD1 1 
ATOM 2331 O OD2 . ASP C 3 82  ? 152.478 134.833 78.579  1.00 82.74  ? 81  ASP c OD2 1 
ATOM 2332 N N   . PRO C 3 83  ? 151.834 132.163 82.848  1.00 72.47  ? 82  PRO c N   1 
ATOM 2333 C CA  . PRO C 3 83  ? 150.982 130.971 82.890  1.00 72.47  ? 82  PRO c CA  1 
ATOM 2334 C C   . PRO C 3 83  ? 150.092 130.881 81.660  1.00 72.47  ? 82  PRO c C   1 
ATOM 2335 O O   . PRO C 3 83  ? 149.600 131.888 81.150  1.00 72.47  ? 82  PRO c O   1 
ATOM 2336 C CB  . PRO C 3 83  ? 150.158 131.170 84.167  1.00 72.47  ? 82  PRO c CB  1 
ATOM 2337 C CG  . PRO C 3 83  ? 150.960 132.123 84.990  1.00 72.47  ? 82  PRO c CG  1 
ATOM 2338 C CD  . PRO C 3 83  ? 151.603 133.043 84.004  1.00 72.47  ? 82  PRO c CD  1 
ATOM 2339 N N   . SER C 3 84  ? 149.888 129.656 81.188  1.00 64.20  ? 83  SER c N   1 
ATOM 2340 C CA  . SER C 3 84  ? 149.011 129.384 80.061  1.00 64.20  ? 83  SER c CA  1 
ATOM 2341 C C   . SER C 3 84  ? 147.961 128.375 80.492  1.00 64.20  ? 83  SER c C   1 
ATOM 2342 O O   . SER C 3 84  ? 148.284 127.375 81.139  1.00 64.20  ? 83  SER c O   1 
ATOM 2343 C CB  . SER C 3 84  ? 149.790 128.850 78.857  1.00 64.20  ? 83  SER c CB  1 
ATOM 2344 O OG  . SER C 3 84  ? 150.347 127.579 79.137  1.00 64.20  ? 83  SER c OG  1 
ATOM 2345 N N   . VAL C 3 85  ? 146.707 128.640 80.130  1.00 55.81  ? 84  VAL c N   1 
ATOM 2346 C CA  . VAL C 3 85  ? 145.600 127.815 80.599  1.00 55.81  ? 84  VAL c CA  1 
ATOM 2347 C C   . VAL C 3 85  ? 145.758 126.406 80.044  1.00 55.81  ? 84  VAL c C   1 
ATOM 2348 O O   . VAL C 3 85  ? 145.606 126.174 78.840  1.00 55.81  ? 84  VAL c O   1 
ATOM 2349 C CB  . VAL C 3 85  ? 144.253 128.425 80.195  1.00 55.81  ? 84  VAL c CB  1 
ATOM 2350 C CG1 . VAL C 3 85  ? 143.120 127.504 80.592  1.00 55.81  ? 84  VAL c CG1 1 
ATOM 2351 C CG2 . VAL C 3 85  ? 144.083 129.789 80.837  1.00 55.81  ? 84  VAL c CG2 1 
ATOM 2352 N N   . THR C 3 86  ? 146.062 125.458 80.928  1.00 54.56  ? 85  THR c N   1 
ATOM 2353 C CA  . THR C 3 86  ? 146.236 124.066 80.536  1.00 54.56  ? 85  THR c CA  1 
ATOM 2354 C C   . THR C 3 86  ? 144.921 123.412 80.140  1.00 54.56  ? 85  THR c C   1 
ATOM 2355 O O   . THR C 3 86  ? 144.845 122.762 79.093  1.00 54.56  ? 85  THR c O   1 
ATOM 2356 C CB  . THR C 3 86  ? 146.880 123.272 81.675  1.00 54.56  ? 85  THR c CB  1 
ATOM 2357 O OG1 . THR C 3 86  ? 148.159 123.835 81.989  1.00 54.56  ? 85  THR c OG1 1 
ATOM 2358 C CG2 . THR C 3 86  ? 147.059 121.821 81.276  1.00 54.56  ? 85  THR c CG2 1 
ATOM 2359 N N   . ARG C 3 87  ? 143.880 123.581 80.952  1.00 47.70  ? 86  ARG c N   1 
ATOM 2360 C CA  . ARG C 3 87  ? 142.591 122.969 80.658  1.00 47.70  ? 86  ARG c CA  1 
ATOM 2361 C C   . ARG C 3 87  ? 141.525 123.694 81.462  1.00 47.70  ? 86  ARG c C   1 
ATOM 2362 O O   . ARG C 3 87  ? 141.818 124.617 82.222  1.00 47.70  ? 86  ARG c O   1 
ATOM 2363 C CB  . ARG C 3 87  ? 142.600 121.474 80.978  1.00 47.70  ? 86  ARG c CB  1 
ATOM 2364 C CG  . ARG C 3 87  ? 142.800 121.182 82.445  1.00 47.70  ? 86  ARG c CG  1 
ATOM 2365 C CD  . ARG C 3 87  ? 142.811 119.699 82.734  1.00 47.70  ? 86  ARG c CD  1 
ATOM 2366 N NE  . ARG C 3 87  ? 142.986 119.451 84.158  1.00 47.70  ? 86  ARG c NE  1 
ATOM 2367 C CZ  . ARG C 3 87  ? 144.163 119.320 84.754  1.00 47.70  ? 86  ARG c CZ  1 
ATOM 2368 N NH1 . ARG C 3 87  ? 145.293 119.398 84.073  1.00 47.70  ? 86  ARG c NH1 1 
ATOM 2369 N NH2 . ARG C 3 87  ? 144.206 119.108 86.065  1.00 47.70  ? 86  ARG c NH2 1 
ATOM 2370 N N   . GLN C 3 88  ? 140.278 123.266 81.285  1.00 41.36  ? 87  GLN c N   1 
ATOM 2371 C CA  . GLN C 3 88  ? 139.176 123.852 82.031  1.00 41.36  ? 87  GLN c CA  1 
ATOM 2372 C C   . GLN C 3 88  ? 137.984 122.911 82.011  1.00 41.36  ? 87  GLN c C   1 
ATOM 2373 O O   . GLN C 3 88  ? 137.799 122.134 81.071  1.00 41.36  ? 87  GLN c O   1 
ATOM 2374 C CB  . GLN C 3 88  ? 138.783 125.221 81.472  1.00 41.36  ? 87  GLN c CB  1 
ATOM 2375 C CG  . GLN C 3 88  ? 138.698 125.270 79.968  1.00 41.36  ? 87  GLN c CG  1 
ATOM 2376 C CD  . GLN C 3 88  ? 138.708 126.686 79.447  1.00 41.36  ? 87  GLN c CD  1 
ATOM 2377 O OE1 . GLN C 3 88  ? 138.722 126.912 78.238  1.00 41.36  ? 87  GLN c OE1 1 
ATOM 2378 N NE2 . GLN C 3 88  ? 138.700 127.651 80.356  1.00 41.36  ? 87  GLN c NE2 1 
ATOM 2379 N N   . ALA C 3 89  ? 137.179 122.993 83.064  1.00 35.42  ? 88  ALA c N   1 
ATOM 2380 C CA  . ALA C 3 89  ? 135.983 122.179 83.221  1.00 35.42  ? 88  ALA c CA  1 
ATOM 2381 C C   . ALA C 3 89  ? 134.763 123.082 83.125  1.00 35.42  ? 88  ALA c C   1 
ATOM 2382 O O   . ALA C 3 89  ? 134.637 124.041 83.892  1.00 35.42  ? 88  ALA c O   1 
ATOM 2383 C CB  . ALA C 3 89  ? 136.000 121.438 84.557  1.00 35.42  ? 88  ALA c CB  1 
ATOM 2384 N N   . TYR C 3 90  ? 133.870 122.772 82.192  1.00 33.60  ? 89  TYR c N   1 
ATOM 2385 C CA  . TYR C 3 90  ? 132.661 123.552 82.002  1.00 33.60  ? 89  TYR c CA  1 
ATOM 2386 C C   . TYR C 3 90  ? 131.490 122.926 82.752  1.00 33.60  ? 89  TYR c C   1 
ATOM 2387 O O   . TYR C 3 90  ? 131.566 121.808 83.263  1.00 33.60  ? 89  TYR c O   1 
ATOM 2388 C CB  . TYR C 3 90  ? 132.322 123.671 80.518  1.00 33.60  ? 89  TYR c CB  1 
ATOM 2389 C CG  . TYR C 3 90  ? 133.475 124.097 79.646  1.00 33.60  ? 89  TYR c CG  1 
ATOM 2390 C CD1 . TYR C 3 90  ? 134.145 125.286 79.881  1.00 33.60  ? 89  TYR c CD1 1 
ATOM 2391 C CD2 . TYR C 3 90  ? 133.886 123.315 78.579  1.00 33.60  ? 89  TYR c CD2 1 
ATOM 2392 C CE1 . TYR C 3 90  ? 135.195 125.680 79.082  1.00 33.60  ? 89  TYR c CE1 1 
ATOM 2393 C CE2 . TYR C 3 90  ? 134.935 123.701 77.775  1.00 33.60  ? 89  TYR c CE2 1 
ATOM 2394 C CZ  . TYR C 3 90  ? 135.586 124.885 78.031  1.00 33.60  ? 89  TYR c CZ  1 
ATOM 2395 O OH  . TYR C 3 90  ? 136.635 125.275 77.232  1.00 33.60  ? 89  TYR c OH  1 
ATOM 2396 N N   . ALA C 3 91  ? 130.391 123.674 82.809  1.00 30.36  ? 90  ALA c N   1 
ATOM 2397 C CA  . ALA C 3 91  ? 129.132 123.229 83.385  1.00 30.36  ? 90  ALA c CA  1 
ATOM 2398 C C   . ALA C 3 91  ? 128.071 124.254 83.032  1.00 30.36  ? 90  ALA c C   1 
ATOM 2399 O O   . ALA C 3 91  ? 128.351 125.453 83.027  1.00 30.36  ? 90  ALA c O   1 
ATOM 2400 C CB  . ALA C 3 91  ? 129.227 123.070 84.906  1.00 30.36  ? 90  ALA c CB  1 
ATOM 2401 N N   . ASP C 3 92  ? 126.863 123.785 82.732  1.00 31.34  ? 91  ASP c N   1 
ATOM 2402 C CA  . ASP C 3 92  ? 125.780 124.703 82.415  1.00 31.34  ? 91  ASP c CA  1 
ATOM 2403 C C   . ASP C 3 92  ? 124.445 124.027 82.678  1.00 31.34  ? 91  ASP c C   1 
ATOM 2404 O O   . ASP C 3 92  ? 124.293 122.823 82.467  1.00 31.34  ? 91  ASP c O   1 
ATOM 2405 C CB  . ASP C 3 92  ? 125.861 125.190 80.964  1.00 31.34  ? 91  ASP c CB  1 
ATOM 2406 C CG  . ASP C 3 92  ? 125.892 124.057 79.965  1.00 31.34  ? 91  ASP c CG  1 
ATOM 2407 O OD1 . ASP C 3 92  ? 124.864 123.370 79.807  1.00 31.34  ? 91  ASP c OD1 1 
ATOM 2408 O OD2 . ASP C 3 92  ? 126.950 123.853 79.335  1.00 31.34  ? 91  ASP c OD2 1 
ATOM 2409 N N   . VAL C 3 93  ? 123.480 124.817 83.140  1.00 29.20  ? 92  VAL c N   1 
ATOM 2410 C CA  . VAL C 3 93  ? 122.142 124.334 83.453  1.00 29.20  ? 92  VAL c CA  1 
ATOM 2411 C C   . VAL C 3 93  ? 121.128 125.256 82.792  1.00 29.20  ? 92  VAL c C   1 
ATOM 2412 O O   . VAL C 3 93  ? 121.295 126.480 82.797  1.00 29.20  ? 92  VAL c O   1 
ATOM 2413 C CB  . VAL C 3 93  ? 121.913 124.246 84.977  1.00 29.20  ? 92  VAL c CB  1 
ATOM 2414 C CG1 . VAL C 3 93  ? 122.168 125.581 85.635  1.00 29.20  ? 92  VAL c CG1 1 
ATOM 2415 C CG2 . VAL C 3 93  ? 120.512 123.762 85.279  1.00 29.20  ? 92  VAL c CG2 1 
ATOM 2416 N N   . THR C 3 94  ? 120.087 124.669 82.204  1.00 29.62  ? 93  THR c N   1 
ATOM 2417 C CA  . THR C 3 94  ? 119.114 125.411 81.408  1.00 29.62  ? 93  THR c CA  1 
ATOM 2418 C C   . THR C 3 94  ? 117.705 125.049 81.853  1.00 29.62  ? 93  THR c C   1 
ATOM 2419 O O   . THR C 3 94  ? 117.252 123.924 81.627  1.00 29.62  ? 93  THR c O   1 
ATOM 2420 C CB  . THR C 3 94  ? 119.294 125.120 79.920  1.00 29.62  ? 93  THR c CB  1 
ATOM 2421 O OG1 . THR C 3 94  ? 120.633 125.444 79.528  1.00 29.62  ? 93  THR c OG1 1 
ATOM 2422 C CG2 . THR C 3 94  ? 118.318 125.942 79.099  1.00 29.62  ? 93  THR c CG2 1 
ATOM 2423 N N   . PHE C 3 95  ? 117.010 126.002 82.467  1.00 30.12  ? 94  PHE c N   1 
ATOM 2424 C CA  . PHE C 3 95  ? 115.612 125.834 82.832  1.00 30.12  ? 94  PHE c CA  1 
ATOM 2425 C C   . PHE C 3 95  ? 114.715 126.389 81.733  1.00 30.12  ? 94  PHE c C   1 
ATOM 2426 O O   . PHE C 3 95  ? 115.047 127.378 81.077  1.00 30.12  ? 94  PHE c O   1 
ATOM 2427 C CB  . PHE C 3 95  ? 115.309 126.531 84.155  1.00 30.12  ? 94  PHE c CB  1 
ATOM 2428 C CG  . PHE C 3 95  ? 116.235 126.150 85.272  1.00 30.12  ? 94  PHE c CG  1 
ATOM 2429 C CD1 . PHE C 3 95  ? 117.420 126.827 85.470  1.00 30.12  ? 94  PHE c CD1 1 
ATOM 2430 C CD2 . PHE C 3 95  ? 115.911 125.120 86.132  1.00 30.12  ? 94  PHE c CD2 1 
ATOM 2431 C CE1 . PHE C 3 95  ? 118.265 126.480 86.500  1.00 30.12  ? 94  PHE c CE1 1 
ATOM 2432 C CE2 . PHE C 3 95  ? 116.754 124.770 87.161  1.00 30.12  ? 94  PHE c CE2 1 
ATOM 2433 C CZ  . PHE C 3 95  ? 117.931 125.450 87.345  1.00 30.12  ? 94  PHE c CZ  1 
ATOM 2434 N N   . SER C 3 96  ? 113.572 125.738 81.532  1.00 34.37  ? 95  SER c N   1 
ATOM 2435 C CA  . SER C 3 96  ? 112.719 126.010 80.377  1.00 34.37  ? 95  SER c CA  1 
ATOM 2436 C C   . SER C 3 96  ? 111.252 126.123 80.785  1.00 34.37  ? 95  SER c C   1 
ATOM 2437 O O   . SER C 3 96  ? 110.374 125.487 80.202  1.00 34.37  ? 95  SER c O   1 
ATOM 2438 C CB  . SER C 3 96  ? 112.903 124.937 79.308  1.00 34.37  ? 95  SER c CB  1 
ATOM 2439 O OG  . SER C 3 96  ? 112.018 125.146 78.224  1.00 34.37  ? 95  SER c OG  1 
ATOM 2440 N N   . PHE C 3 97  ? 110.971 126.928 81.807  1.00 36.95  ? 96  PHE c N   1 
ATOM 2441 C CA  . PHE C 3 97  ? 109.598 127.127 82.245  1.00 36.95  ? 96  PHE c CA  1 
ATOM 2442 C C   . PHE C 3 97  ? 108.767 127.789 81.147  1.00 36.95  ? 96  PHE c C   1 
ATOM 2443 O O   . PHE C 3 97  ? 109.287 128.350 80.182  1.00 36.95  ? 96  PHE c O   1 
ATOM 2444 C CB  . PHE C 3 97  ? 109.555 127.976 83.510  1.00 36.95  ? 96  PHE c CB  1 
ATOM 2445 C CG  . PHE C 3 97  ? 110.616 127.633 84.501  1.00 36.95  ? 96  PHE c CG  1 
ATOM 2446 C CD1 . PHE C 3 97  ? 110.583 126.428 85.175  1.00 36.95  ? 96  PHE c CD1 1 
ATOM 2447 C CD2 . PHE C 3 97  ? 111.647 128.513 84.763  1.00 36.95  ? 96  PHE c CD2 1 
ATOM 2448 C CE1 . PHE C 3 97  ? 111.558 126.106 86.088  1.00 36.95  ? 96  PHE c CE1 1 
ATOM 2449 C CE2 . PHE C 3 97  ? 112.625 128.197 85.679  1.00 36.95  ? 96  PHE c CE2 1 
ATOM 2450 C CZ  . PHE C 3 97  ? 112.580 126.991 86.342  1.00 36.95  ? 96  PHE c CZ  1 
ATOM 2451 N N   . THR C 3 98  ? 107.451 127.718 81.311  1.00 41.94  ? 97  THR c N   1 
ATOM 2452 C CA  . THR C 3 98  ? 106.493 128.193 80.320  1.00 41.94  ? 97  THR c CA  1 
ATOM 2453 C C   . THR C 3 98  ? 105.796 129.455 80.823  1.00 41.94  ? 97  THR c C   1 
ATOM 2454 O O   . THR C 3 98  ? 106.113 129.989 81.887  1.00 41.94  ? 97  THR c O   1 
ATOM 2455 C CB  . THR C 3 98  ? 105.469 127.106 79.985  1.00 41.94  ? 97  THR c CB  1 
ATOM 2456 O OG1 . THR C 3 98  ? 104.550 127.600 79.005  1.00 41.94  ? 97  THR c OG1 1 
ATOM 2457 C CG2 . THR C 3 98  ? 104.704 126.702 81.225  1.00 41.94  ? 97  THR c CG2 1 
ATOM 2458 N N   . GLN C 3 99  ? 104.827 129.924 80.034  1.00 47.27  ? 98  GLN c N   1 
ATOM 2459 C CA  . GLN C 3 99  ? 104.196 131.213 80.307  1.00 47.27  ? 98  GLN c CA  1 
ATOM 2460 C C   . GLN C 3 99  ? 103.316 131.167 81.548  1.00 47.27  ? 98  GLN c C   1 
ATOM 2461 O O   . GLN C 3 99  ? 103.269 132.134 82.315  1.00 47.27  ? 98  GLN c O   1 
ATOM 2462 C CB  . GLN C 3 99  ? 103.377 131.657 79.098  1.00 47.27  ? 98  GLN c CB  1 
ATOM 2463 C CG  . GLN C 3 99  ? 102.906 133.095 79.166  1.00 47.27  ? 98  GLN c CG  1 
ATOM 2464 C CD  . GLN C 3 99  ? 101.996 133.458 78.011  1.00 47.27  ? 98  GLN c CD  1 
ATOM 2465 O OE1 . GLN C 3 99  ? 101.293 132.607 77.469  1.00 47.27  ? 98  GLN c OE1 1 
ATOM 2466 N NE2 . GLN C 3 99  ? 102.004 134.729 77.629  1.00 47.27  ? 98  GLN c NE2 1 
ATOM 2467 N N   . TYR C 3 100 ? 102.605 130.062 81.761  1.00 43.74  ? 99  TYR c N   1 
ATOM 2468 C CA  . TYR C 3 100 ? 101.628 129.958 82.836  1.00 43.74  ? 99  TYR c CA  1 
ATOM 2469 C C   . TYR C 3 100 ? 102.183 129.289 84.083  1.00 43.74  ? 99  TYR c C   1 
ATOM 2470 O O   . TYR C 3 100 ? 101.414 128.964 84.991  1.00 43.74  ? 99  TYR c O   1 
ATOM 2471 C CB  . TYR C 3 100 ? 100.392 129.199 82.354  1.00 43.74  ? 99  TYR c CB  1 
ATOM 2472 C CG  . TYR C 3 100 ? 99.514  129.990 81.418  1.00 43.74  ? 99  TYR c CG  1 
ATOM 2473 C CD1 . TYR C 3 100 ? 98.575  130.884 81.910  1.00 43.74  ? 99  TYR c CD1 1 
ATOM 2474 C CD2 . TYR C 3 100 ? 99.617  129.839 80.044  1.00 43.74  ? 99  TYR c CD2 1 
ATOM 2475 C CE1 . TYR C 3 100 ? 97.771  131.610 81.062  1.00 43.74  ? 99  TYR c CE1 1 
ATOM 2476 C CE2 . TYR C 3 100 ? 98.815  130.560 79.187  1.00 43.74  ? 99  TYR c CE2 1 
ATOM 2477 C CZ  . TYR C 3 100 ? 97.894  131.444 79.702  1.00 43.74  ? 99  TYR c CZ  1 
ATOM 2478 O OH  . TYR C 3 100 ? 97.090  132.167 78.854  1.00 43.74  ? 99  TYR c OH  1 
ATOM 2479 N N   . SER C 3 101 ? 103.493 129.083 84.155  1.00 42.42  ? 100 SER c N   1 
ATOM 2480 C CA  . SER C 3 101 ? 104.081 128.364 85.277  1.00 42.42  ? 100 SER c CA  1 
ATOM 2481 C C   . SER C 3 101 ? 103.986 129.200 86.545  1.00 42.42  ? 100 SER c C   1 
ATOM 2482 O O   . SER C 3 101 ? 104.481 130.330 86.590  1.00 42.42  ? 100 SER c O   1 
ATOM 2483 C CB  . SER C 3 101 ? 105.534 128.021 84.972  1.00 42.42  ? 100 SER c CB  1 
ATOM 2484 O OG  . SER C 3 101 ? 106.306 129.199 84.836  1.00 42.42  ? 100 SER c OG  1 
ATOM 2485 N N   . THR C 3 102 ? 103.360 128.643 87.577  1.00 43.49  ? 101 THR c N   1 
ATOM 2486 C CA  . THR C 3 102 ? 103.240 129.347 88.842  1.00 43.49  ? 101 THR c CA  1 
ATOM 2487 C C   . THR C 3 102 ? 104.582 129.382 89.565  1.00 43.49  ? 101 THR c C   1 
ATOM 2488 O O   . THR C 3 102 ? 105.518 128.649 89.237  1.00 43.49  ? 101 THR c O   1 
ATOM 2489 C CB  . THR C 3 102 ? 102.182 128.695 89.731  1.00 43.49  ? 101 THR c CB  1 
ATOM 2490 O OG1 . THR C 3 102 ? 102.002 129.478 90.916  1.00 43.49  ? 101 THR c OG1 1 
ATOM 2491 C CG2 . THR C 3 102 ? 102.600 127.295 90.123  1.00 43.49  ? 101 THR c CG2 1 
ATOM 2492 N N   . ASP C 3 103 ? 104.666 130.260 90.565  1.00 45.22  ? 102 ASP c N   1 
ATOM 2493 C CA  . ASP C 3 103 ? 105.921 130.462 91.282  1.00 45.22  ? 102 ASP c CA  1 
ATOM 2494 C C   . ASP C 3 103 ? 106.332 129.215 92.055  1.00 45.22  ? 102 ASP c C   1 
ATOM 2495 O O   . ASP C 3 103 ? 107.524 128.902 92.135  1.00 45.22  ? 102 ASP c O   1 
ATOM 2496 C CB  . ASP C 3 103 ? 105.780 131.659 92.223  1.00 45.22  ? 102 ASP c CB  1 
ATOM 2497 C CG  . ASP C 3 103 ? 107.097 132.079 92.854  1.00 45.22  ? 102 ASP c CG  1 
ATOM 2498 O OD1 . ASP C 3 103 ? 108.134 131.437 92.598  1.00 45.22  ? 102 ASP c OD1 1 
ATOM 2499 O OD2 . ASP C 3 103 ? 107.091 133.068 93.618  1.00 45.22  ? 102 ASP c OD2 1 
ATOM 2500 N N   . GLU C 3 104 ? 105.367 128.490 92.622  1.00 44.15  ? 103 GLU c N   1 
ATOM 2501 C CA  . GLU C 3 104 ? 105.694 127.340 93.458  1.00 44.15  ? 103 GLU c CA  1 
ATOM 2502 C C   . GLU C 3 104 ? 106.379 126.237 92.661  1.00 44.15  ? 103 GLU c C   1 
ATOM 2503 O O   . GLU C 3 104 ? 107.329 125.616 93.148  1.00 44.15  ? 103 GLU c O   1 
ATOM 2504 C CB  . GLU C 3 104 ? 104.430 126.809 94.130  1.00 44.15  ? 103 GLU c CB  1 
ATOM 2505 C CG  . GLU C 3 104 ? 104.106 127.481 95.454  1.00 44.15  ? 103 GLU c CG  1 
ATOM 2506 C CD  . GLU C 3 104 ? 103.566 128.892 95.291  1.00 44.15  ? 103 GLU c CD  1 
ATOM 2507 O OE1 . GLU C 3 104 ? 103.351 129.328 94.141  1.00 44.15  ? 103 GLU c OE1 1 
ATOM 2508 O OE2 . GLU C 3 104 ? 103.360 129.570 96.319  1.00 44.15  ? 103 GLU c OE2 1 
ATOM 2509 N N   . GLU C 3 105 ? 105.913 125.970 91.440  1.00 42.99  ? 104 GLU c N   1 
ATOM 2510 C CA  . GLU C 3 105 ? 106.482 124.862 90.681  1.00 42.99  ? 104 GLU c CA  1 
ATOM 2511 C C   . GLU C 3 105 ? 107.805 125.249 90.032  1.00 42.99  ? 104 GLU c C   1 
ATOM 2512 O O   . GLU C 3 105 ? 108.643 124.383 89.760  1.00 42.99  ? 104 GLU c O   1 
ATOM 2513 C CB  . GLU C 3 105 ? 105.485 124.366 89.636  1.00 42.99  ? 104 GLU c CB  1 
ATOM 2514 C CG  . GLU C 3 105 ? 105.159 125.352 88.541  1.00 42.99  ? 104 GLU c CG  1 
ATOM 2515 C CD  . GLU C 3 105 ? 104.117 124.811 87.588  1.00 42.99  ? 104 GLU c CD  1 
ATOM 2516 O OE1 . GLU C 3 105 ? 103.645 123.678 87.810  1.00 42.99  ? 104 GLU c OE1 1 
ATOM 2517 O OE2 . GLU C 3 105 ? 103.771 125.508 86.615  1.00 42.99  ? 104 GLU c OE2 1 
ATOM 2518 N N   . ARG C 3 106 ? 108.008 126.540 89.761  1.00 39.81  ? 105 ARG c N   1 
ATOM 2519 C CA  . ARG C 3 106 ? 109.327 126.989 89.329  1.00 39.81  ? 105 ARG c CA  1 
ATOM 2520 C C   . ARG C 3 106 ? 110.350 126.863 90.447  1.00 39.81  ? 105 ARG c C   1 
ATOM 2521 O O   . ARG C 3 106 ? 111.497 126.480 90.196  1.00 39.81  ? 105 ARG c O   1 
ATOM 2522 C CB  . ARG C 3 106 ? 109.268 128.432 88.833  1.00 39.81  ? 105 ARG c CB  1 
ATOM 2523 C CG  . ARG C 3 106 ? 108.615 128.591 87.484  1.00 39.81  ? 105 ARG c CG  1 
ATOM 2524 C CD  . ARG C 3 106 ? 108.795 129.998 86.962  1.00 39.81  ? 105 ARG c CD  1 
ATOM 2525 N NE  . ARG C 3 106 ? 108.521 130.995 87.987  1.00 39.81  ? 105 ARG c NE  1 
ATOM 2526 C CZ  . ARG C 3 106 ? 107.542 131.885 87.917  1.00 39.81  ? 105 ARG c CZ  1 
ATOM 2527 N NH1 . ARG C 3 106 ? 106.727 131.932 86.878  1.00 39.81  ? 105 ARG c NH1 1 
ATOM 2528 N NH2 . ARG C 3 106 ? 107.377 132.749 88.913  1.00 39.81  ? 105 ARG c NH2 1 
ATOM 2529 N N   . ALA C 3 107 ? 109.957 127.176 91.676  1.00 37.68  ? 106 ALA c N   1 
ATOM 2530 C CA  . ALA C 3 107 ? 110.828 127.037 92.830  1.00 37.68  ? 106 ALA c CA  1 
ATOM 2531 C C   . ALA C 3 107 ? 110.999 125.593 93.266  1.00 37.68  ? 106 ALA c C   1 
ATOM 2532 O O   . ALA C 3 107 ? 111.836 125.319 94.127  1.00 37.68  ? 106 ALA c O   1 
ATOM 2533 C CB  . ALA C 3 107 ? 110.288 127.861 94.001  1.00 37.68  ? 106 ALA c CB  1 
ATOM 2534 N N   . PHE C 3 108 ? 110.224 124.668 92.703  1.00 36.38  ? 107 PHE c N   1 
ATOM 2535 C CA  . PHE C 3 108 ? 110.361 123.253 93.019  1.00 36.38  ? 107 PHE c CA  1 
ATOM 2536 C C   . PHE C 3 108 ? 111.459 122.590 92.200  1.00 36.38  ? 107 PHE c C   1 
ATOM 2537 O O   . PHE C 3 108 ? 112.172 121.724 92.711  1.00 36.38  ? 107 PHE c O   1 
ATOM 2538 C CB  . PHE C 3 108 ? 109.033 122.532 92.786  1.00 36.38  ? 107 PHE c CB  1 
ATOM 2539 C CG  . PHE C 3 108 ? 109.002 121.132 93.315  1.00 36.38  ? 107 PHE c CG  1 
ATOM 2540 C CD1 . PHE C 3 108 ? 108.718 120.890 94.645  1.00 36.38  ? 107 PHE c CD1 1 
ATOM 2541 C CD2 . PHE C 3 108 ? 109.246 120.057 92.482  1.00 36.38  ? 107 PHE c CD2 1 
ATOM 2542 C CE1 . PHE C 3 108 ? 108.686 119.605 95.137  1.00 36.38  ? 107 PHE c CE1 1 
ATOM 2543 C CE2 . PHE C 3 108 ? 109.215 118.769 92.968  1.00 36.38  ? 107 PHE c CE2 1 
ATOM 2544 C CZ  . PHE C 3 108 ? 108.933 118.543 94.298  1.00 36.38  ? 107 PHE c CZ  1 
ATOM 2545 N N   . VAL C 3 109 ? 111.607 122.987 90.936  1.00 34.89  ? 108 VAL c N   1 
ATOM 2546 C CA  . VAL C 3 109 ? 112.634 122.401 90.083  1.00 34.89  ? 108 VAL c CA  1 
ATOM 2547 C C   . VAL C 3 109 ? 114.022 122.837 90.528  1.00 34.89  ? 108 VAL c C   1 
ATOM 2548 O O   . VAL C 3 109 ? 114.964 122.037 90.535  1.00 34.89  ? 108 VAL c O   1 
ATOM 2549 C CB  . VAL C 3 109 ? 112.373 122.769 88.613  1.00 34.89  ? 108 VAL c CB  1 
ATOM 2550 C CG1 . VAL C 3 109 ? 113.426 122.156 87.721  1.00 34.89  ? 108 VAL c CG1 1 
ATOM 2551 C CG2 . VAL C 3 109 ? 110.992 122.310 88.198  1.00 34.89  ? 108 VAL c CG2 1 
ATOM 2552 N N   . ARG C 3 110 ? 114.175 124.109 90.900  1.00 34.15  ? 109 ARG c N   1 
ATOM 2553 C CA  . ARG C 3 110 ? 115.497 124.633 91.227  1.00 34.15  ? 109 ARG c CA  1 
ATOM 2554 C C   . ARG C 3 110 ? 116.089 123.925 92.438  1.00 34.15  ? 109 ARG c C   1 
ATOM 2555 O O   . ARG C 3 110 ? 117.275 123.577 92.448  1.00 34.15  ? 109 ARG c O   1 
ATOM 2556 C CB  . ARG C 3 110 ? 115.418 126.137 91.476  1.00 34.15  ? 109 ARG c CB  1 
ATOM 2557 C CG  . ARG C 3 110 ? 116.510 126.662 92.386  1.00 34.15  ? 109 ARG c CG  1 
ATOM 2558 C CD  . ARG C 3 110 ? 116.268 128.104 92.761  1.00 34.15  ? 109 ARG c CD  1 
ATOM 2559 N NE  . ARG C 3 110 ? 115.324 128.221 93.864  1.00 34.15  ? 109 ARG c NE  1 
ATOM 2560 C CZ  . ARG C 3 110 ? 115.601 127.919 95.125  1.00 34.15  ? 109 ARG c CZ  1 
ATOM 2561 N NH1 . ARG C 3 110 ? 116.798 127.491 95.486  1.00 34.15  ? 109 ARG c NH1 1 
ATOM 2562 N NH2 . ARG C 3 110 ? 114.653 128.055 96.047  1.00 34.15  ? 109 ARG c NH2 1 
ATOM 2563 N N   . THR C 3 111 ? 115.284 123.707 93.471  1.00 34.18  ? 110 THR c N   1 
ATOM 2564 C CA  . THR C 3 111 ? 115.763 123.049 94.677  1.00 34.18  ? 110 THR c CA  1 
ATOM 2565 C C   . THR C 3 111 ? 115.630 121.535 94.624  1.00 34.18  ? 110 THR c C   1 
ATOM 2566 O O   . THR C 3 111 ? 116.149 120.853 95.512  1.00 34.18  ? 110 THR c O   1 
ATOM 2567 C CB  . THR C 3 111 ? 115.023 123.574 95.901  1.00 34.18  ? 110 THR c CB  1 
ATOM 2568 O OG1 . THR C 3 111 ? 115.468 122.863 97.060  1.00 34.18  ? 110 THR c OG1 1 
ATOM 2569 C CG2 . THR C 3 111 ? 113.557 123.348 95.732  1.00 34.18  ? 110 THR c CG2 1 
ATOM 2570 N N   . GLU C 3 112 ? 114.936 120.990 93.626  1.00 35.59  ? 111 GLU c N   1 
ATOM 2571 C CA  . GLU C 3 112 ? 115.027 119.556 93.385  1.00 35.59  ? 111 GLU c CA  1 
ATOM 2572 C C   . GLU C 3 112 ? 116.354 119.208 92.731  1.00 35.59  ? 111 GLU c C   1 
ATOM 2573 O O   . GLU C 3 112 ? 116.973 118.195 93.071  1.00 35.59  ? 111 GLU c O   1 
ATOM 2574 C CB  . GLU C 3 112 ? 113.860 119.086 92.518  1.00 35.59  ? 111 GLU c CB  1 
ATOM 2575 C CG  . GLU C 3 112 ? 114.095 117.767 91.810  1.00 35.59  ? 111 GLU c CG  1 
ATOM 2576 C CD  . GLU C 3 112 ? 112.880 117.302 91.034  1.00 35.59  ? 111 GLU c CD  1 
ATOM 2577 O OE1 . GLU C 3 112 ? 111.805 117.914 91.196  1.00 35.59  ? 111 GLU c OE1 1 
ATOM 2578 O OE2 . GLU C 3 112 ? 112.996 116.326 90.264  1.00 35.59  ? 111 GLU c OE2 1 
ATOM 2579 N N   . LEU C 3 113 ? 116.806 120.044 91.796  1.00 32.68  ? 112 LEU c N   1 
ATOM 2580 C CA  . LEU C 3 113 ? 118.127 119.860 91.209  1.00 32.68  ? 112 LEU c CA  1 
ATOM 2581 C C   . LEU C 3 113 ? 119.220 120.053 92.249  1.00 32.68  ? 112 LEU c C   1 
ATOM 2582 O O   . LEU C 3 113 ? 120.207 119.312 92.267  1.00 32.68  ? 112 LEU c O   1 
ATOM 2583 C CB  . LEU C 3 113 ? 118.314 120.830 90.045  1.00 32.68  ? 112 LEU c CB  1 
ATOM 2584 C CG  . LEU C 3 113 ? 119.679 120.837 89.369  1.00 32.68  ? 112 LEU c CG  1 
ATOM 2585 C CD1 . LEU C 3 113 ? 119.970 119.477 88.772  1.00 32.68  ? 112 LEU c CD1 1 
ATOM 2586 C CD2 . LEU C 3 113 ? 119.719 121.907 88.302  1.00 32.68  ? 112 LEU c CD2 1 
ATOM 2587 N N   . ALA C 3 114 ? 119.064 121.052 93.121  1.00 32.51  ? 113 ALA c N   1 
ATOM 2588 C CA  . ALA C 3 114 ? 120.067 121.306 94.149  1.00 32.51  ? 113 ALA c CA  1 
ATOM 2589 C C   . ALA C 3 114 ? 120.165 120.148 95.132  1.00 32.51  ? 113 ALA c C   1 
ATOM 2590 O O   . ALA C 3 114 ? 121.269 119.740 95.509  1.00 32.51  ? 113 ALA c O   1 
ATOM 2591 C CB  . ALA C 3 114 ? 119.743 122.604 94.885  1.00 32.51  ? 113 ALA c CB  1 
ATOM 2592 N N   . ALA C 3 115 ? 119.027 119.607 95.560  1.00 33.18  ? 114 ALA c N   1 
ATOM 2593 C CA  . ALA C 3 115 ? 119.020 118.483 96.485  1.00 33.18  ? 114 ALA c CA  1 
ATOM 2594 C C   . ALA C 3 115 ? 119.414 117.173 95.825  1.00 33.18  ? 114 ALA c C   1 
ATOM 2595 O O   . ALA C 3 115 ? 119.680 116.197 96.533  1.00 33.18  ? 114 ALA c O   1 
ATOM 2596 C CB  . ALA C 3 115 ? 117.639 118.328 97.120  1.00 33.18  ? 114 ALA c CB  1 
ATOM 2597 N N   . LEU C 3 116 ? 119.445 117.126 94.498  1.00 32.30  ? 115 LEU c N   1 
ATOM 2598 C CA  . LEU C 3 116 ? 119.855 115.940 93.766  1.00 32.30  ? 115 LEU c CA  1 
ATOM 2599 C C   . LEU C 3 116 ? 121.346 115.926 93.474  1.00 32.30  ? 115 LEU c C   1 
ATOM 2600 O O   . LEU C 3 116 ? 121.927 114.845 93.347  1.00 32.30  ? 115 LEU c O   1 
ATOM 2601 C CB  . LEU C 3 116 ? 119.068 115.844 92.455  1.00 32.30  ? 115 LEU c CB  1 
ATOM 2602 C CG  . LEU C 3 116 ? 119.123 114.553 91.650  1.00 32.30  ? 115 LEU c CG  1 
ATOM 2603 C CD1 . LEU C 3 116 ? 118.320 113.478 92.345  1.00 32.30  ? 115 LEU c CD1 1 
ATOM 2604 C CD2 . LEU C 3 116 ? 118.579 114.807 90.261  1.00 32.30  ? 115 LEU c CD2 1 
ATOM 2605 N N   . LEU C 3 117 ? 121.978 117.095 93.397  1.00 32.21  ? 116 LEU c N   1 
ATOM 2606 C CA  . LEU C 3 117 ? 123.415 117.196 93.196  1.00 32.21  ? 116 LEU c CA  1 
ATOM 2607 C C   . LEU C 3 117 ? 124.203 116.870 94.454  1.00 32.21  ? 116 LEU c C   1 
ATOM 2608 O O   . LEU C 3 117 ? 125.435 116.812 94.396  1.00 32.21  ? 116 LEU c O   1 
ATOM 2609 C CB  . LEU C 3 117 ? 123.776 118.602 92.717  1.00 32.21  ? 116 LEU c CB  1 
ATOM 2610 C CG  . LEU C 3 117 ? 123.628 118.884 91.224  1.00 32.21  ? 116 LEU c CG  1 
ATOM 2611 C CD1 . LEU C 3 117 ? 123.760 120.368 90.959  1.00 32.21  ? 116 LEU c CD1 1 
ATOM 2612 C CD2 . LEU C 3 117 ? 124.655 118.110 90.429  1.00 32.21  ? 116 LEU c CD2 1 
ATOM 2613 N N   . ALA C 3 118 ? 123.526 116.674 95.582  1.00 33.35  ? 117 ALA c N   1 
ATOM 2614 C CA  . ALA C 3 118 ? 124.156 116.250 96.822  1.00 33.35  ? 117 ALA c CA  1 
ATOM 2615 C C   . ALA C 3 118 ? 123.813 114.816 97.195  1.00 33.35  ? 117 ALA c C   1 
ATOM 2616 O O   . ALA C 3 118 ? 124.291 114.328 98.223  1.00 33.35  ? 117 ALA c O   1 
ATOM 2617 C CB  . ALA C 3 118 ? 123.760 117.188 97.965  1.00 33.35  ? 117 ALA c CB  1 
ATOM 2618 N N   . SER C 3 119 ? 122.995 114.136 96.398  1.00 34.91  ? 118 SER c N   1 
ATOM 2619 C CA  . SER C 3 119 ? 122.681 112.745 96.651  1.00 34.91  ? 118 SER c CA  1 
ATOM 2620 C C   . SER C 3 119 ? 123.885 111.872 96.312  1.00 34.91  ? 118 SER c C   1 
ATOM 2621 O O   . SER C 3 119 ? 124.762 112.283 95.551  1.00 34.91  ? 118 SER c O   1 
ATOM 2622 C CB  . SER C 3 119 ? 121.471 112.316 95.828  1.00 34.91  ? 118 SER c CB  1 
ATOM 2623 O OG  . SER C 3 119 ? 121.837 112.083 94.481  1.00 34.91  ? 118 SER c OG  1 
ATOM 2624 N N   . PRO C 3 120 ? 123.957 110.664 96.877  1.00 35.89  ? 119 PRO c N   1 
ATOM 2625 C CA  . PRO C 3 120 ? 125.087 109.779 96.550  1.00 35.89  ? 119 PRO c CA  1 
ATOM 2626 C C   . PRO C 3 120 ? 125.189 109.449 95.074  1.00 35.89  ? 119 PRO c C   1 
ATOM 2627 O O   . PRO C 3 120 ? 126.302 109.261 94.566  1.00 35.89  ? 119 PRO c O   1 
ATOM 2628 C CB  . PRO C 3 120 ? 124.797 108.527 97.387  1.00 35.89  ? 119 PRO c CB  1 
ATOM 2629 C CG  . PRO C 3 120 ? 123.964 109.019 98.510  1.00 35.89  ? 119 PRO c CG  1 
ATOM 2630 C CD  . PRO C 3 120 ? 123.097 110.084 97.920  1.00 35.89  ? 119 PRO c CD  1 
ATOM 2631 N N   . LEU C 3 121 ? 124.058 109.383 94.369  1.00 36.45  ? 120 LEU c N   1 
ATOM 2632 C CA  . LEU C 3 121 ? 124.074 108.980 92.967  1.00 36.45  ? 120 LEU c CA  1 
ATOM 2633 C C   . LEU C 3 121 ? 124.923 109.926 92.127  1.00 36.45  ? 120 LEU c C   1 
ATOM 2634 O O   . LEU C 3 121 ? 125.849 109.496 91.432  1.00 36.45  ? 120 LEU c O   1 
ATOM 2635 C CB  . LEU C 3 121 ? 122.645 108.919 92.434  1.00 36.45  ? 120 LEU c CB  1 
ATOM 2636 C CG  . LEU C 3 121 ? 122.478 108.800 90.922  1.00 36.45  ? 120 LEU c CG  1 
ATOM 2637 C CD1 . LEU C 3 121 ? 122.779 107.385 90.467  1.00 36.45  ? 120 LEU c CD1 1 
ATOM 2638 C CD2 . LEU C 3 121 ? 121.076 109.212 90.514  1.00 36.45  ? 120 LEU c CD2 1 
ATOM 2639 N N   . LEU C 3 122 ? 124.646 111.228 92.201  1.00 34.47  ? 121 LEU c N   1 
ATOM 2640 C CA  . LEU C 3 122 ? 125.425 112.169 91.409  1.00 34.47  ? 121 LEU c CA  1 
ATOM 2641 C C   . LEU C 3 122 ? 126.807 112.426 91.989  1.00 34.47  ? 121 LEU c C   1 
ATOM 2642 O O   . LEU C 3 122 ? 127.718 112.772 91.232  1.00 34.47  ? 121 LEU c O   1 
ATOM 2643 C CB  . LEU C 3 122 ? 124.674 113.487 91.237  1.00 34.47  ? 121 LEU c CB  1 
ATOM 2644 C CG  . LEU C 3 122 ? 123.422 113.341 90.376  1.00 34.47  ? 121 LEU c CG  1 
ATOM 2645 C CD1 . LEU C 3 122 ? 122.640 114.634 90.315  1.00 34.47  ? 121 LEU c CD1 1 
ATOM 2646 C CD2 . LEU C 3 122 ? 123.804 112.880 88.989  1.00 34.47  ? 121 LEU c CD2 1 
ATOM 2647 N N   . ILE C 3 123 ? 126.996 112.243 93.296  1.00 35.72  ? 122 ILE c N   1 
ATOM 2648 C CA  . ILE C 3 123 ? 128.346 112.289 93.850  1.00 35.72  ? 122 ILE c CA  1 
ATOM 2649 C C   . ILE C 3 123 ? 129.224 111.244 93.176  1.00 35.72  ? 122 ILE c C   1 
ATOM 2650 O O   . ILE C 3 123 ? 130.324 111.545 92.698  1.00 35.72  ? 122 ILE c O   1 
ATOM 2651 C CB  . ILE C 3 123 ? 128.317 112.096 95.376  1.00 35.72  ? 122 ILE c CB  1 
ATOM 2652 C CG1 . ILE C 3 123 ? 127.840 113.368 96.070  1.00 35.72  ? 122 ILE c CG1 1 
ATOM 2653 C CG2 . ILE C 3 123 ? 129.686 111.692 95.887  1.00 35.72  ? 122 ILE c CG2 1 
ATOM 2654 C CD1 . ILE C 3 123 ? 127.760 113.236 97.564  1.00 35.72  ? 122 ILE c CD1 1 
ATOM 2655 N N   . ASP C 3 124 ? 128.740 110.002 93.106  1.00 38.72  ? 123 ASP c N   1 
ATOM 2656 C CA  . ASP C 3 124 ? 129.508 108.961 92.431  1.00 38.72  ? 123 ASP c CA  1 
ATOM 2657 C C   . ASP C 3 124 ? 129.572 109.186 90.927  1.00 38.72  ? 123 ASP c C   1 
ATOM 2658 O O   . ASP C 3 124 ? 130.569 108.825 90.294  1.00 38.72  ? 123 ASP c O   1 
ATOM 2659 C CB  . ASP C 3 124 ? 128.925 107.581 92.736  1.00 38.72  ? 123 ASP c CB  1 
ATOM 2660 C CG  . ASP C 3 124 ? 128.928 107.259 94.219  1.00 38.72  ? 123 ASP c CG  1 
ATOM 2661 O OD1 . ASP C 3 124 ? 127.839 107.040 94.788  1.00 38.72  ? 123 ASP c OD1 1 
ATOM 2662 O OD2 . ASP C 3 124 ? 130.023 107.221 94.816  1.00 38.72  ? 123 ASP c OD2 1 
ATOM 2663 N N   . ALA C 3 125 ? 128.532 109.776 90.335  1.00 36.39  ? 124 ALA c N   1 
ATOM 2664 C CA  . ALA C 3 125 ? 128.520 109.961 88.889  1.00 36.39  ? 124 ALA c CA  1 
ATOM 2665 C C   . ALA C 3 125 ? 129.449 111.073 88.422  1.00 36.39  ? 124 ALA c C   1 
ATOM 2666 O O   . ALA C 3 125 ? 129.913 111.027 87.280  1.00 36.39  ? 124 ALA c O   1 
ATOM 2667 C CB  . ALA C 3 125 ? 127.099 110.244 88.406  1.00 36.39  ? 124 ALA c CB  1 
ATOM 2668 N N   . ILE C 3 126 ? 129.727 112.070 89.259  1.00 35.79  ? 125 ILE c N   1 
ATOM 2669 C CA  . ILE C 3 126 ? 130.549 113.204 88.868  1.00 35.79  ? 125 ILE c CA  1 
ATOM 2670 C C   . ILE C 3 126 ? 131.955 113.117 89.450  1.00 35.79  ? 125 ILE c C   1 
ATOM 2671 O O   . ILE C 3 126 ? 132.934 113.335 88.735  1.00 35.79  ? 125 ILE c O   1 
ATOM 2672 C CB  . ILE C 3 126 ? 129.873 114.535 89.260  1.00 35.79  ? 125 ILE c CB  1 
ATOM 2673 C CG1 . ILE C 3 126 ? 128.534 114.678 88.542  1.00 35.79  ? 125 ILE c CG1 1 
ATOM 2674 C CG2 . ILE C 3 126 ? 130.762 115.704 88.904  1.00 35.79  ? 125 ILE c CG2 1 
ATOM 2675 C CD1 . ILE C 3 126 ? 127.567 115.600 89.239  1.00 35.79  ? 125 ILE c CD1 1 
ATOM 2676 N N   . ASP C 3 127 ? 132.082 112.808 90.743  1.00 40.42  ? 126 ASP c N   1 
ATOM 2677 C CA  . ASP C 3 127 ? 133.403 112.792 91.360  1.00 40.42  ? 126 ASP c CA  1 
ATOM 2678 C C   . ASP C 3 127 ? 134.302 111.711 90.772  1.00 40.42  ? 126 ASP c C   1 
ATOM 2679 O O   . ASP C 3 127 ? 135.482 111.968 90.513  1.00 40.42  ? 126 ASP c O   1 
ATOM 2680 C CB  . ASP C 3 127 ? 133.280 112.605 92.869  1.00 40.42  ? 126 ASP c CB  1 
ATOM 2681 C CG  . ASP C 3 127 ? 132.679 113.809 93.554  1.00 40.42  ? 126 ASP c CG  1 
ATOM 2682 O OD1 . ASP C 3 127 ? 132.843 114.929 93.031  1.00 40.42  ? 126 ASP c OD1 1 
ATOM 2683 O OD2 . ASP C 3 127 ? 132.051 113.641 94.619  1.00 40.42  ? 126 ASP c OD2 1 
ATOM 2684 N N   . GLN C 3 128 ? 133.776 110.506 90.551  1.00 40.28  ? 127 GLN c N   1 
ATOM 2685 C CA  . GLN C 3 128 ? 134.581 109.408 90.038  1.00 40.28  ? 127 GLN c CA  1 
ATOM 2686 C C   . GLN C 3 128 ? 134.265 109.024 88.602  1.00 40.28  ? 127 GLN c C   1 
ATOM 2687 O O   . GLN C 3 128 ? 135.002 108.216 88.027  1.00 40.28  ? 127 GLN c O   1 
ATOM 2688 C CB  . GLN C 3 128 ? 134.428 108.163 90.925  1.00 40.28  ? 127 GLN c CB  1 
ATOM 2689 C CG  . GLN C 3 128 ? 134.980 108.318 92.327  1.00 40.28  ? 127 GLN c CG  1 
ATOM 2690 C CD  . GLN C 3 128 ? 133.937 108.798 93.309  1.00 40.28  ? 127 GLN c CD  1 
ATOM 2691 O OE1 . GLN C 3 128 ? 132.739 108.730 93.039  1.00 40.28  ? 127 GLN c OE1 1 
ATOM 2692 N NE2 . GLN C 3 128 ? 134.384 109.278 94.462  1.00 40.28  ? 127 GLN c NE2 1 
ATOM 2693 N N   . LEU C 3 129 ? 133.205 109.571 88.009  1.00 37.38  ? 128 LEU c N   1 
ATOM 2694 C CA  . LEU C 3 129 ? 132.848 109.319 86.614  1.00 37.38  ? 128 LEU c CA  1 
ATOM 2695 C C   . LEU C 3 129 ? 132.595 107.832 86.361  1.00 37.38  ? 128 LEU c C   1 
ATOM 2696 O O   . LEU C 3 129 ? 133.273 107.185 85.562  1.00 37.38  ? 128 LEU c O   1 
ATOM 2697 C CB  . LEU C 3 129 ? 133.923 109.859 85.665  1.00 37.38  ? 128 LEU c CB  1 
ATOM 2698 C CG  . LEU C 3 129 ? 134.129 111.369 85.620  1.00 37.38  ? 128 LEU c CG  1 
ATOM 2699 C CD1 . LEU C 3 129 ? 135.097 111.726 84.513  1.00 37.38  ? 128 LEU c CD1 1 
ATOM 2700 C CD2 . LEU C 3 129 ? 132.806 112.075 85.416  1.00 37.38  ? 128 LEU c CD2 1 
ATOM 2701 N N   . ASN C 3 130 ? 131.596 107.295 87.059  1.00 38.08  ? 129 ASN c N   1 
ATOM 2702 C CA  . ASN C 3 130 ? 131.152 105.931 86.820  1.00 38.08  ? 129 ASN c CA  1 
ATOM 2703 C C   . ASN C 3 130 ? 129.641 105.934 86.626  1.00 38.08  ? 129 ASN c C   1 
ATOM 2704 O O   . ASN C 3 130 ? 128.913 106.532 87.435  1.00 38.08  ? 129 ASN c O   1 
ATOM 2705 C CB  . ASN C 3 130 ? 131.545 104.991 87.965  1.00 38.08  ? 129 ASN c CB  1 
ATOM 2706 C CG  . ASN C 3 130 ? 131.201 105.548 89.321  1.00 38.08  ? 129 ASN c CG  1 
ATOM 2707 O OD1 . ASN C 3 130 ? 131.945 106.347 89.880  1.00 38.08  ? 129 ASN c OD1 1 
ATOM 2708 N ND2 . ASN C 3 130 ? 130.072 105.119 89.866  1.00 38.08  ? 129 ASN c ND2 1 
ATOM 2709 N N   . PRO C 3 131 ? 129.132 105.280 85.584  1.00 39.07  ? 130 PRO c N   1 
ATOM 2710 C CA  . PRO C 3 131 ? 127.693 105.340 85.299  1.00 39.07  ? 130 PRO c CA  1 
ATOM 2711 C C   . PRO C 3 131 ? 126.851 104.607 86.329  1.00 39.07  ? 130 PRO c C   1 
ATOM 2712 O O   . PRO C 3 131 ? 127.366 104.134 87.346  1.00 39.07  ? 130 PRO c O   1 
ATOM 2713 C CB  . PRO C 3 131 ? 127.586 104.670 83.923  1.00 39.07  ? 130 PRO c CB  1 
ATOM 2714 C CG  . PRO C 3 131 ? 128.957 104.765 83.341  1.00 39.07  ? 130 PRO c CG  1 
ATOM 2715 C CD  . PRO C 3 131 ? 129.875 104.613 84.505  1.00 39.07  ? 130 PRO c CD  1 
ATOM 2716 N N   . ALA C 3 132 ? 125.551 104.510 86.073  1.00 38.93  ? 131 ALA c N   1 
ATOM 2717 C CA  . ALA C 3 132 ? 124.645 103.798 86.966  1.00 38.93  ? 131 ALA c CA  1 
ATOM 2718 C C   . ALA C 3 132 ? 124.178 102.489 86.338  1.00 38.93  ? 131 ALA c C   1 
ATOM 2719 O O   . ALA C 3 132 ? 124.254 101.428 86.958  1.00 38.93  ? 131 ALA c O   1 
ATOM 2720 C CB  . ALA C 3 132 ? 123.457 104.670 87.316  1.00 38.93  ? 131 ALA c CB  1 
ATOM 2721 N N   . ALA D 3 2   ? 127.388 104.083 91.214  1.00 45.55  ? 1   ALA C N   1 
ATOM 2722 C CA  . ALA D 3 2   ? 127.144 102.700 91.600  1.00 45.55  ? 1   ALA C CA  1 
ATOM 2723 C C   . ALA D 3 2   ? 125.765 102.252 91.142  1.00 45.55  ? 1   ALA C C   1 
ATOM 2724 O O   . ALA D 3 2   ? 125.125 102.923 90.334  1.00 45.55  ? 1   ALA C O   1 
ATOM 2725 C CB  . ALA D 3 2   ? 127.283 102.535 93.104  1.00 45.55  ? 1   ALA C CB  1 
ATOM 2726 N N   . LYS D 3 3   ? 125.313 101.112 91.658  1.00 45.67  ? 2   LYS C N   1 
ATOM 2727 C CA  . LYS D 3 3   ? 123.981 100.626 91.330  1.00 45.67  ? 2   LYS C CA  1 
ATOM 2728 C C   . LYS D 3 3   ? 122.931 101.602 91.838  1.00 45.67  ? 2   LYS C C   1 
ATOM 2729 O O   . LYS D 3 3   ? 122.965 102.023 92.997  1.00 45.67  ? 2   LYS C O   1 
ATOM 2730 C CB  . LYS D 3 3   ? 123.759 99.238  91.931  1.00 45.67  ? 2   LYS C CB  1 
ATOM 2731 C CG  . LYS D 3 3   ? 124.806 98.223  91.511  1.00 45.67  ? 2   LYS C CG  1 
ATOM 2732 C CD  . LYS D 3 3   ? 124.857 98.090  89.996  1.00 45.67  ? 2   LYS C CD  1 
ATOM 2733 C CE  . LYS D 3 3   ? 126.284 97.937  89.493  1.00 45.67  ? 2   LYS C CE  1 
ATOM 2734 N NZ  . LYS D 3 3   ? 126.401 98.350  88.069  1.00 45.67  ? 2   LYS C NZ  1 
ATOM 2735 N N   . LEU D 3 4   ? 122.000 101.962 90.963  1.00 43.54  ? 3   LEU C N   1 
ATOM 2736 C CA  . LEU D 3 4   ? 121.003 102.966 91.301  1.00 43.54  ? 3   LEU C CA  1 
ATOM 2737 C C   . LEU D 3 4   ? 119.952 102.386 92.239  1.00 43.54  ? 3   LEU C C   1 
ATOM 2738 O O   . LEU D 3 4   ? 119.529 101.237 92.093  1.00 43.54  ? 3   LEU C O   1 
ATOM 2739 C CB  . LEU D 3 4   ? 120.361 103.520 90.027  1.00 43.54  ? 3   LEU C CB  1 
ATOM 2740 C CG  . LEU D 3 4   ? 119.384 102.683 89.198  1.00 43.54  ? 3   LEU C CG  1 
ATOM 2741 C CD1 . LEU D 3 4   ? 118.659 103.579 88.211  1.00 43.54  ? 3   LEU C CD1 1 
ATOM 2742 C CD2 . LEU D 3 4   ? 120.081 101.553 88.463  1.00 43.54  ? 3   LEU C CD2 1 
ATOM 2743 N N   . GLU D 3 5   ? 119.547 103.188 93.217  1.00 45.94  ? 4   GLU C N   1 
ATOM 2744 C CA  . GLU D 3 5   ? 118.601 102.793 94.251  1.00 45.94  ? 4   GLU C CA  1 
ATOM 2745 C C   . GLU D 3 5   ? 117.452 103.798 94.306  1.00 45.94  ? 4   GLU C C   1 
ATOM 2746 O O   . GLU D 3 5   ? 117.306 104.657 93.434  1.00 45.94  ? 4   GLU C O   1 
ATOM 2747 C CB  . GLU D 3 5   ? 119.303 102.676 95.604  1.00 45.94  ? 4   GLU C CB  1 
ATOM 2748 C CG  . GLU D 3 5   ? 119.835 101.290 95.912  1.00 45.94  ? 4   GLU C CG  1 
ATOM 2749 C CD  . GLU D 3 5   ? 120.580 101.234 97.232  1.00 45.94  ? 4   GLU C CD  1 
ATOM 2750 O OE1 . GLU D 3 5   ? 121.550 102.002 97.404  1.00 45.94  ? 4   GLU C OE1 1 
ATOM 2751 O OE2 . GLU D 3 5   ? 120.194 100.422 98.099  1.00 45.94  ? 4   GLU C OE2 1 
ATOM 2752 N N   . THR D 3 6   ? 116.633 103.683 95.347  1.00 40.60  ? 5   THR C N   1 
ATOM 2753 C CA  . THR D 3 6   ? 115.490 104.573 95.536  1.00 40.60  ? 5   THR C CA  1 
ATOM 2754 C C   . THR D 3 6   ? 115.973 105.858 96.194  1.00 40.60  ? 5   THR C C   1 
ATOM 2755 O O   . THR D 3 6   ? 116.167 105.915 97.410  1.00 40.60  ? 5   THR C O   1 
ATOM 2756 C CB  . THR D 3 6   ? 114.412 103.899 96.375  1.00 40.60  ? 5   THR C CB  1 
ATOM 2757 O OG1 . THR D 3 6   ? 114.949 103.559 97.658  1.00 40.60  ? 5   THR C OG1 1 
ATOM 2758 C CG2 . THR D 3 6   ? 113.920 102.639 95.688  1.00 40.60  ? 5   THR C CG2 1 
ATOM 2759 N N   . VAL D 3 7   ? 116.166 106.898 95.385  1.00 37.32  ? 6   VAL C N   1 
ATOM 2760 C CA  . VAL D 3 7   ? 116.622 108.181 95.902  1.00 37.32  ? 6   VAL C CA  1 
ATOM 2761 C C   . VAL D 3 7   ? 115.444 108.931 96.505  1.00 37.32  ? 6   VAL C C   1 
ATOM 2762 O O   . VAL D 3 7   ? 114.402 109.102 95.860  1.00 37.32  ? 6   VAL C O   1 
ATOM 2763 C CB  . VAL D 3 7   ? 117.290 108.998 94.787  1.00 37.32  ? 6   VAL C CB  1 
ATOM 2764 C CG1 . VAL D 3 7   ? 117.431 110.448 95.200  1.00 37.32  ? 6   VAL C CG1 1 
ATOM 2765 C CG2 . VAL D 3 7   ? 118.645 108.409 94.439  1.00 37.32  ? 6   VAL C CG2 1 
ATOM 2766 N N   . THR D 3 8   ? 115.600 109.381 97.747  1.00 37.72  ? 7   THR C N   1 
ATOM 2767 C CA  . THR D 3 8   ? 114.587 110.175 98.432  1.00 37.72  ? 7   THR C CA  1 
ATOM 2768 C C   . THR D 3 8   ? 115.150 111.563 98.694  1.00 37.72  ? 7   THR C C   1 
ATOM 2769 O O   . THR D 3 8   ? 116.201 111.700 99.328  1.00 37.72  ? 7   THR C O   1 
ATOM 2770 C CB  . THR D 3 8   ? 114.158 109.525 99.746  1.00 37.72  ? 7   THR C CB  1 
ATOM 2771 O OG1 . THR D 3 8   ? 115.215 109.645 100.704 1.00 37.72  ? 7   THR C OG1 1 
ATOM 2772 C CG2 . THR D 3 8   ? 113.842 108.055 99.534  1.00 37.72  ? 7   THR C CG2 1 
ATOM 2773 N N   . LEU D 3 9   ? 114.449 112.584 98.217  1.00 36.17  ? 8   LEU C N   1 
ATOM 2774 C CA  . LEU D 3 9   ? 114.839 113.974 98.412  1.00 36.17  ? 8   LEU C CA  1 
ATOM 2775 C C   . LEU D 3 9   ? 113.866 114.612 99.392  1.00 36.17  ? 8   LEU C C   1 
ATOM 2776 O O   . LEU D 3 9   ? 112.652 114.591 99.166  1.00 36.17  ? 8   LEU C O   1 
ATOM 2777 C CB  . LEU D 3 9   ? 114.845 114.728 97.084  1.00 36.17  ? 8   LEU C CB  1 
ATOM 2778 C CG  . LEU D 3 9   ? 115.600 114.041 95.948  1.00 36.17  ? 8   LEU C CG  1 
ATOM 2779 C CD1 . LEU D 3 9   ? 115.333 114.733 94.628  1.00 36.17  ? 8   LEU C CD1 1 
ATOM 2780 C CD2 . LEU D 3 9   ? 117.085 114.011 96.248  1.00 36.17  ? 8   LEU C CD2 1 
ATOM 2781 N N   . GLY D 3 10  ? 114.395 115.170 100.475 1.00 38.77  ? 9   GLY C N   1 
ATOM 2782 C CA  . GLY D 3 10  ? 113.554 115.758 101.496 1.00 38.77  ? 9   GLY C CA  1 
ATOM 2783 C C   . GLY D 3 10  ? 113.827 117.227 101.734 1.00 38.77  ? 9   GLY C C   1 
ATOM 2784 O O   . GLY D 3 10  ? 114.892 117.732 101.371 1.00 38.77  ? 9   GLY C O   1 
ATOM 2785 N N   . ASN D 3 11  ? 112.862 117.920 102.341 1.00 42.81  ? 10  ASN C N   1 
ATOM 2786 C CA  . ASN D 3 11  ? 112.996 119.335 102.685 1.00 42.81  ? 10  ASN C CA  1 
ATOM 2787 C C   . ASN D 3 11  ? 113.272 120.190 101.451 1.00 42.81  ? 10  ASN C C   1 
ATOM 2788 O O   . ASN D 3 11  ? 114.220 120.975 101.420 1.00 42.81  ? 10  ASN C O   1 
ATOM 2789 C CB  . ASN D 3 11  ? 114.086 119.546 103.737 1.00 42.81  ? 10  ASN C CB  1 
ATOM 2790 C CG  . ASN D 3 11  ? 113.810 118.797 105.019 1.00 42.81  ? 10  ASN C CG  1 
ATOM 2791 O OD1 . ASN D 3 11  ? 114.508 117.843 105.354 1.00 42.81  ? 10  ASN C OD1 1 
ATOM 2792 N ND2 . ASN D 3 11  ? 112.788 119.226 105.748 1.00 42.81  ? 10  ASN C ND2 1 
ATOM 2793 N N   . ILE D 3 12  ? 112.442 120.040 100.422 1.00 40.82  ? 11  ILE C N   1 
ATOM 2794 C CA  . ILE D 3 12  ? 112.635 120.781 99.184  1.00 40.82  ? 11  ILE C CA  1 
ATOM 2795 C C   . ILE D 3 12  ? 111.335 121.453 98.769  1.00 40.82  ? 11  ILE C C   1 
ATOM 2796 O O   . ILE D 3 12  ? 110.235 121.003 99.102  1.00 40.82  ? 11  ILE C O   1 
ATOM 2797 C CB  . ILE D 3 12  ? 113.155 119.880 98.044  1.00 40.82  ? 11  ILE C CB  1 
ATOM 2798 C CG1 . ILE D 3 12  ? 112.145 118.786 97.717  1.00 40.82  ? 11  ILE C CG1 1 
ATOM 2799 C CG2 . ILE D 3 12  ? 114.475 119.258 98.426  1.00 40.82  ? 11  ILE C CG2 1 
ATOM 2800 C CD1 . ILE D 3 12  ? 112.478 118.017 96.469  1.00 40.82  ? 11  ILE C CD1 1 
ATOM 2801 N N   . GLY D 3 13  ? 111.484 122.554 98.043  1.00 42.92  ? 12  GLY C N   1 
ATOM 2802 C CA  . GLY D 3 13  ? 110.419 123.226 97.325  1.00 42.92  ? 12  GLY C CA  1 
ATOM 2803 C C   . GLY D 3 13  ? 109.896 124.472 98.004  1.00 42.92  ? 12  GLY C C   1 
ATOM 2804 O O   . GLY D 3 13  ? 108.987 124.409 98.834  1.00 42.92  ? 12  GLY C O   1 
ATOM 2805 N N   . LYS D 3 14  ? 110.484 125.616 97.650  1.00 46.02  ? 13  LYS C N   1 
ATOM 2806 C CA  . LYS D 3 14  ? 109.981 126.957 97.939  1.00 46.02  ? 13  LYS C CA  1 
ATOM 2807 C C   . LYS D 3 14  ? 109.917 127.251 99.436  1.00 46.02  ? 13  LYS C C   1 
ATOM 2808 O O   . LYS D 3 14  ? 109.837 128.416 99.842  1.00 46.02  ? 13  LYS C O   1 
ATOM 2809 C CB  . LYS D 3 14  ? 108.604 127.136 97.284  1.00 46.02  ? 13  LYS C CB  1 
ATOM 2810 C CG  . LYS D 3 14  ? 107.856 128.403 97.665  1.00 46.02  ? 13  LYS C CG  1 
ATOM 2811 C CD  . LYS D 3 14  ? 107.806 129.394 96.519  1.00 46.02  ? 13  LYS C CD  1 
ATOM 2812 C CE  . LYS D 3 14  ? 107.317 130.748 97.001  1.00 46.02  ? 13  LYS C CE  1 
ATOM 2813 N NZ  . LYS D 3 14  ? 107.441 131.795 95.953  1.00 46.02  ? 13  LYS C NZ  1 
ATOM 2814 N N   . ASP D 3 15  ? 110.047 126.217 100.263 1.00 48.98  ? 14  ASP C N   1 
ATOM 2815 C CA  . ASP D 3 15  ? 109.903 126.328 101.709 1.00 48.98  ? 14  ASP C CA  1 
ATOM 2816 C C   . ASP D 3 15  ? 110.055 124.941 102.313 1.00 48.98  ? 14  ASP C C   1 
ATOM 2817 O O   . ASP D 3 15  ? 109.918 123.929 101.622 1.00 48.98  ? 14  ASP C O   1 
ATOM 2818 C CB  . ASP D 3 15  ? 108.547 126.910 102.114 1.00 48.98  ? 14  ASP C CB  1 
ATOM 2819 C CG  . ASP D 3 15  ? 107.419 125.905 101.975 1.00 48.98  ? 14  ASP C CG  1 
ATOM 2820 O OD1 . ASP D 3 15  ? 107.342 125.233 100.926 1.00 48.98  ? 14  ASP C OD1 1 
ATOM 2821 O OD2 . ASP D 3 15  ? 106.611 125.781 102.918 1.00 48.98  ? 14  ASP C OD2 1 
ATOM 2822 N N   . GLY D 3 16  ? 110.345 124.916 103.611 1.00 49.57  ? 15  GLY C N   1 
ATOM 2823 C CA  . GLY D 3 16  ? 110.116 123.765 104.464 1.00 49.57  ? 15  GLY C CA  1 
ATOM 2824 C C   . GLY D 3 16  ? 110.358 122.388 103.884 1.00 49.57  ? 15  GLY C C   1 
ATOM 2825 O O   . GLY D 3 16  ? 111.436 122.102 103.359 1.00 49.57  ? 15  GLY C O   1 
ATOM 2826 N N   . LYS D 3 17  ? 109.340 121.532 103.963 1.00 46.97  ? 16  LYS C N   1 
ATOM 2827 C CA  . LYS D 3 17  ? 109.463 120.113 103.659 1.00 46.97  ? 16  LYS C CA  1 
ATOM 2828 C C   . LYS D 3 17  ? 108.444 119.711 102.604 1.00 46.97  ? 16  LYS C C   1 
ATOM 2829 O O   . LYS D 3 17  ? 107.245 119.958 102.768 1.00 46.97  ? 16  LYS C O   1 
ATOM 2830 C CB  . LYS D 3 17  ? 109.271 119.274 104.925 1.00 46.97  ? 16  LYS C CB  1 
ATOM 2831 C CG  . LYS D 3 17  ? 109.107 117.782 104.673 1.00 46.97  ? 16  LYS C CG  1 
ATOM 2832 C CD  . LYS D 3 17  ? 107.661 117.351 104.893 1.00 46.97  ? 16  LYS C CD  1 
ATOM 2833 C CE  . LYS D 3 17  ? 107.488 115.851 104.732 1.00 46.97  ? 16  LYS C CE  1 
ATOM 2834 N NZ  . LYS D 3 17  ? 106.087 115.428 104.998 1.00 46.97  ? 16  LYS C NZ  1 
ATOM 2835 N N   . GLN D 3 18  ? 108.927 119.087 101.527 1.00 43.99  ? 17  GLN C N   1 
ATOM 2836 C CA  . GLN D 3 18  ? 108.080 118.386 100.558 1.00 43.99  ? 17  GLN C CA  1 
ATOM 2837 C C   . GLN D 3 18  ? 108.920 117.235 100.000 1.00 43.99  ? 17  GLN C C   1 
ATOM 2838 O O   . GLN D 3 18  ? 109.680 117.415 99.048  1.00 43.99  ? 17  GLN C O   1 
ATOM 2839 C CB  . GLN D 3 18  ? 107.590 119.304 99.449  1.00 43.99  ? 17  GLN C CB  1 
ATOM 2840 C CG  . GLN D 3 18  ? 106.347 120.099 99.782  1.00 43.99  ? 17  GLN C CG  1 
ATOM 2841 C CD  . GLN D 3 18  ? 106.085 121.196 98.777  1.00 43.99  ? 17  GLN C CD  1 
ATOM 2842 O OE1 . GLN D 3 18  ? 106.080 120.959 97.570  1.00 43.99  ? 17  GLN C OE1 1 
ATOM 2843 N NE2 . GLN D 3 18  ? 105.869 122.410 99.268  1.00 43.99  ? 17  GLN C NE2 1 
ATOM 2844 N N   . THR D 3 19  ? 108.766 116.057 100.595 1.00 43.19  ? 18  THR C N   1 
ATOM 2845 C CA  . THR D 3 19  ? 109.578 114.919 100.196 1.00 43.19  ? 18  THR C CA  1 
ATOM 2846 C C   . THR D 3 19  ? 109.226 114.468 98.782  1.00 43.19  ? 18  THR C C   1 
ATOM 2847 O O   . THR D 3 19  ? 108.172 114.801 98.234  1.00 43.19  ? 18  THR C O   1 
ATOM 2848 C CB  . THR D 3 19  ? 109.401 113.756 101.172 1.00 43.19  ? 18  THR C CB  1 
ATOM 2849 O OG1 . THR D 3 19  ? 108.022 113.370 101.216 1.00 43.19  ? 18  THR C OG1 1 
ATOM 2850 C CG2 . THR D 3 19  ? 109.864 114.154 102.563 1.00 43.19  ? 18  THR C CG2 1 
ATOM 2851 N N   . LEU D 3 20  ? 110.138 113.700 98.189  1.00 38.39  ? 19  LEU C N   1 
ATOM 2852 C CA  . LEU D 3 20  ? 109.954 113.211 96.826  1.00 38.39  ? 19  LEU C CA  1 
ATOM 2853 C C   . LEU D 3 20  ? 110.795 111.954 96.666  1.00 38.39  ? 19  LEU C C   1 
ATOM 2854 O O   . LEU D 3 20  ? 112.025 112.038 96.609  1.00 38.39  ? 19  LEU C O   1 
ATOM 2855 C CB  . LEU D 3 20  ? 110.345 114.282 95.816  1.00 38.39  ? 19  LEU C CB  1 
ATOM 2856 C CG  . LEU D 3 20  ? 110.202 113.975 94.330  1.00 38.39  ? 19  LEU C CG  1 
ATOM 2857 C CD1 . LEU D 3 20  ? 109.606 115.161 93.620  1.00 38.39  ? 19  LEU C CD1 1 
ATOM 2858 C CD2 . LEU D 3 20  ? 111.556 113.669 93.750  1.00 38.39  ? 19  LEU C CD2 1 
ATOM 2859 N N   . VAL D 3 21  ? 110.138 110.801 96.591  1.00 37.58  ? 20  VAL C N   1 
ATOM 2860 C CA  . VAL D 3 21  ? 110.808 109.507 96.555  1.00 37.58  ? 20  VAL C CA  1 
ATOM 2861 C C   . VAL D 3 21  ? 110.860 109.029 95.113  1.00 37.58  ? 20  VAL C C   1 
ATOM 2862 O O   . VAL D 3 21  ? 109.818 108.820 94.481  1.00 37.58  ? 20  VAL C O   1 
ATOM 2863 C CB  . VAL D 3 21  ? 110.092 108.482 97.447  1.00 37.58  ? 20  VAL C CB  1 
ATOM 2864 C CG1 . VAL D 3 21  ? 110.669 107.097 97.230  1.00 37.58  ? 20  VAL C CG1 1 
ATOM 2865 C CG2 . VAL D 3 21  ? 110.199 108.886 98.905  1.00 37.58  ? 20  VAL C CG2 1 
ATOM 2866 N N   . LEU D 3 22  ? 112.070 108.843 94.597  1.00 35.37  ? 21  LEU C N   1 
ATOM 2867 C CA  . LEU D 3 22  ? 112.282 108.404 93.226  1.00 35.37  ? 21  LEU C CA  1 
ATOM 2868 C C   . LEU D 3 22  ? 112.705 106.943 93.216  1.00 35.37  ? 21  LEU C C   1 
ATOM 2869 O O   . LEU D 3 22  ? 113.622 106.551 93.943  1.00 35.37  ? 21  LEU C O   1 
ATOM 2870 C CB  . LEU D 3 22  ? 113.342 109.261 92.535  1.00 35.37  ? 21  LEU C CB  1 
ATOM 2871 C CG  . LEU D 3 22  ? 113.020 110.738 92.329  1.00 35.37  ? 21  LEU C CG  1 
ATOM 2872 C CD1 . LEU D 3 22  ? 114.299 111.520 92.134  1.00 35.37  ? 21  LEU C CD1 1 
ATOM 2873 C CD2 . LEU D 3 22  ? 112.099 110.931 91.142  1.00 35.37  ? 21  LEU C CD2 1 
ATOM 2874 N N   . ASN D 3 23  ? 112.040 106.153 92.397  1.00 36.72  ? 22  ASN C N   1 
ATOM 2875 C CA  . ASN D 3 23  ? 112.277 104.741 92.176  1.00 36.72  ? 22  ASN C CA  1 
ATOM 2876 C C   . ASN D 3 23  ? 112.987 104.526 90.847  1.00 36.72  ? 22  ASN C C   1 
ATOM 2877 O O   . ASN D 3 23  ? 112.699 105.230 89.873  1.00 36.72  ? 22  ASN C O   1 
ATOM 2878 C CB  . ASN D 3 23  ? 110.957 103.963 92.178  1.00 36.72  ? 22  ASN C CB  1 
ATOM 2879 C CG  . ASN D 3 23  ? 110.188 104.130 93.468  1.00 36.72  ? 22  ASN C CG  1 
ATOM 2880 O OD1 . ASN D 3 23  ? 110.749 104.021 94.556  1.00 36.72  ? 22  ASN C OD1 1 
ATOM 2881 N ND2 . ASN D 3 23  ? 108.895 104.403 93.354  1.00 36.72  ? 22  ASN C ND2 1 
ATOM 2882 N N   . PRO D 3 24  ? 113.914 103.574 90.772  1.00 36.14  ? 23  PRO C N   1 
ATOM 2883 C CA  . PRO D 3 24  ? 114.647 103.360 89.520  1.00 36.14  ? 23  PRO C CA  1 
ATOM 2884 C C   . PRO D 3 24  ? 113.763 102.766 88.438  1.00 36.14  ? 23  PRO C C   1 
ATOM 2885 O O   . PRO D 3 24  ? 112.826 102.014 88.712  1.00 36.14  ? 23  PRO C O   1 
ATOM 2886 C CB  . PRO D 3 24  ? 115.768 102.391 89.917  1.00 36.14  ? 23  PRO C CB  1 
ATOM 2887 C CG  . PRO D 3 24  ? 115.405 101.844 91.240  1.00 36.14  ? 23  PRO C CG  1 
ATOM 2888 C CD  . PRO D 3 24  ? 114.221 102.561 91.792  1.00 36.14  ? 23  PRO C CD  1 
ATOM 2889 N N   . ARG D 3 25  ? 114.077 103.115 87.189  1.00 38.05  ? 24  ARG C N   1 
ATOM 2890 C CA  . ARG D 3 25  ? 113.317 102.663 86.029  1.00 38.05  ? 24  ARG C CA  1 
ATOM 2891 C C   . ARG D 3 25  ? 114.197 101.976 84.991  1.00 38.05  ? 24  ARG C C   1 
ATOM 2892 O O   . ARG D 3 25  ? 113.798 101.856 83.830  1.00 38.05  ? 24  ARG C O   1 
ATOM 2893 C CB  . ARG D 3 25  ? 112.571 103.835 85.393  1.00 38.05  ? 24  ARG C CB  1 
ATOM 2894 C CG  . ARG D 3 25  ? 111.059 103.724 85.431  1.00 38.05  ? 24  ARG C CG  1 
ATOM 2895 C CD  . ARG D 3 25  ? 110.530 103.418 86.817  1.00 38.05  ? 24  ARG C CD  1 
ATOM 2896 N NE  . ARG D 3 25  ? 109.079 103.540 86.858  1.00 38.05  ? 24  ARG C NE  1 
ATOM 2897 C CZ  . ARG D 3 25  ? 108.352 103.530 87.967  1.00 38.05  ? 24  ARG C CZ  1 
ATOM 2898 N NH1 . ARG D 3 25  ? 108.905 103.361 89.156  1.00 38.05  ? 24  ARG C NH1 1 
ATOM 2899 N NH2 . ARG D 3 25  ? 107.035 103.691 87.879  1.00 38.05  ? 24  ARG C NH2 1 
ATOM 2900 N N   . GLY D 3 26  ? 115.390 101.533 85.377  1.00 38.99  ? 25  GLY C N   1 
ATOM 2901 C CA  . GLY D 3 26  ? 116.217 100.739 84.490  1.00 38.99  ? 25  GLY C CA  1 
ATOM 2902 C C   . GLY D 3 26  ? 117.008 101.531 83.471  1.00 38.99  ? 25  GLY C C   1 
ATOM 2903 O O   . GLY D 3 26  ? 116.590 102.611 83.048  1.00 38.99  ? 25  GLY C O   1 
ATOM 2904 N N   . VAL D 3 27  ? 118.151 100.990 83.063  1.00 41.69  ? 26  VAL C N   1 
ATOM 2905 C CA  . VAL D 3 27  ? 119.024 101.648 82.099  1.00 41.69  ? 26  VAL C CA  1 
ATOM 2906 C C   . VAL D 3 27  ? 118.540 101.361 80.685  1.00 41.69  ? 26  VAL C C   1 
ATOM 2907 O O   . VAL D 3 27  ? 118.040 100.272 80.383  1.00 41.69  ? 26  VAL C O   1 
ATOM 2908 C CB  . VAL D 3 27  ? 120.481 101.185 82.300  1.00 41.69  ? 26  VAL C CB  1 
ATOM 2909 C CG1 . VAL D 3 27  ? 121.426 101.999 81.437  1.00 41.69  ? 26  VAL C CG1 1 
ATOM 2910 C CG2 . VAL D 3 27  ? 120.869 101.284 83.762  1.00 41.69  ? 26  VAL C CG2 1 
ATOM 2911 N N   . ASN D 3 28  ? 118.689 102.351 79.803  1.00 42.40  ? 27  ASN C N   1 
ATOM 2912 C CA  . ASN D 3 28  ? 118.358 102.185 78.395  1.00 42.40  ? 27  ASN C CA  1 
ATOM 2913 C C   . ASN D 3 28  ? 119.570 101.612 77.673  1.00 42.40  ? 27  ASN C C   1 
ATOM 2914 O O   . ASN D 3 28  ? 120.605 102.288 77.597  1.00 42.40  ? 27  ASN C O   1 
ATOM 2915 C CB  . ASN D 3 28  ? 117.955 103.517 77.782  1.00 42.40  ? 27  ASN C CB  1 
ATOM 2916 C CG  . ASN D 3 28  ? 117.405 103.375 76.379  1.00 42.40  ? 27  ASN C CG  1 
ATOM 2917 O OD1 . ASN D 3 28  ? 117.341 102.277 75.829  1.00 42.40  ? 27  ASN C OD1 1 
ATOM 2918 N ND2 . ASN D 3 28  ? 117.005 104.494 75.788  1.00 42.40  ? 27  ASN C ND2 1 
ATOM 2919 N N   . PRO D 3 29  ? 119.498 100.393 77.136  1.00 43.42  ? 28  PRO C N   1 
ATOM 2920 C CA  . PRO D 3 29  ? 120.687 99.799  76.502  1.00 43.42  ? 28  PRO C CA  1 
ATOM 2921 C C   . PRO D 3 29  ? 121.195 100.562 75.292  1.00 43.42  ? 28  PRO C C   1 
ATOM 2922 O O   . PRO D 3 29  ? 122.405 100.551 75.033  1.00 43.42  ? 28  PRO C O   1 
ATOM 2923 C CB  . PRO D 3 29  ? 120.206 98.394  76.117  1.00 43.42  ? 28  PRO C CB  1 
ATOM 2924 C CG  . PRO D 3 29  ? 118.720 98.518  76.025  1.00 43.42  ? 28  PRO C CG  1 
ATOM 2925 C CD  . PRO D 3 29  ? 118.343 99.482  77.102  1.00 43.42  ? 28  PRO C CD  1 
ATOM 2926 N N   . THR D 3 30  ? 120.312 101.217 74.537  1.00 45.88  ? 29  THR C N   1 
ATOM 2927 C CA  . THR D 3 30  ? 120.729 101.849 73.288  1.00 45.88  ? 29  THR C CA  1 
ATOM 2928 C C   . THR D 3 30  ? 121.713 102.987 73.531  1.00 45.88  ? 29  THR C C   1 
ATOM 2929 O O   . THR D 3 30  ? 122.706 103.118 72.806  1.00 45.88  ? 29  THR C O   1 
ATOM 2930 C CB  . THR D 3 30  ? 119.508 102.356 72.523  1.00 45.88  ? 29  THR C CB  1 
ATOM 2931 O OG1 . THR D 3 30  ? 118.708 103.174 73.386  1.00 45.88  ? 29  THR C OG1 1 
ATOM 2932 C CG2 . THR D 3 30  ? 118.673 101.188 72.029  1.00 45.88  ? 29  THR C CG2 1 
ATOM 2933 N N   . ASN D 3 31  ? 121.460 103.818 74.542  1.00 43.16  ? 30  ASN C N   1 
ATOM 2934 C CA  . ASN D 3 31  ? 122.290 104.987 74.796  1.00 43.16  ? 30  ASN C CA  1 
ATOM 2935 C C   . ASN D 3 31  ? 122.794 105.122 76.227  1.00 43.16  ? 30  ASN C C   1 
ATOM 2936 O O   . ASN D 3 31  ? 123.579 106.038 76.494  1.00 43.16  ? 30  ASN C O   1 
ATOM 2937 C CB  . ASN D 3 31  ? 121.539 106.267 74.395  1.00 43.16  ? 30  ASN C CB  1 
ATOM 2938 C CG  . ASN D 3 31  ? 120.288 106.498 75.217  1.00 43.16  ? 30  ASN C CG  1 
ATOM 2939 O OD1 . ASN D 3 31  ? 120.014 105.782 76.177  1.00 43.16  ? 30  ASN C OD1 1 
ATOM 2940 N ND2 . ASN D 3 31  ? 119.513 107.506 74.834  1.00 43.16  ? 30  ASN C ND2 1 
ATOM 2941 N N   . GLY D 3 32  ? 122.380 104.256 77.148  1.00 39.39  ? 31  GLY C N   1 
ATOM 2942 C CA  . GLY D 3 32  ? 122.978 104.201 78.464  1.00 39.39  ? 31  GLY C CA  1 
ATOM 2943 C C   . GLY D 3 32  ? 122.415 105.144 79.505  1.00 39.39  ? 31  GLY C C   1 
ATOM 2944 O O   . GLY D 3 32  ? 122.996 105.247 80.592  1.00 39.39  ? 31  GLY C O   1 
ATOM 2945 N N   . VAL D 3 33  ? 121.311 105.836 79.223  1.00 37.25  ? 32  VAL C N   1 
ATOM 2946 C CA  . VAL D 3 33  ? 120.736 106.737 80.214  1.00 37.25  ? 32  VAL C CA  1 
ATOM 2947 C C   . VAL D 3 33  ? 120.035 105.929 81.298  1.00 37.25  ? 32  VAL C C   1 
ATOM 2948 O O   . VAL D 3 33  ? 119.282 104.989 81.015  1.00 37.25  ? 32  VAL C O   1 
ATOM 2949 C CB  . VAL D 3 33  ? 119.776 107.740 79.552  1.00 37.25  ? 32  VAL C CB  1 
ATOM 2950 C CG1 . VAL D 3 33  ? 120.544 108.677 78.645  1.00 37.25  ? 32  VAL C CG1 1 
ATOM 2951 C CG2 . VAL D 3 33  ? 118.695 107.025 78.773  1.00 37.25  ? 32  VAL C CG2 1 
ATOM 2952 N N   . ALA D 3 34  ? 120.297 106.281 82.552  1.00 35.36  ? 33  ALA C N   1 
ATOM 2953 C CA  . ALA D 3 34  ? 119.688 105.622 83.699  1.00 35.36  ? 33  ALA C CA  1 
ATOM 2954 C C   . ALA D 3 34  ? 118.511 106.462 84.172  1.00 35.36  ? 33  ALA C C   1 
ATOM 2955 O O   . ALA D 3 34  ? 118.679 107.640 84.499  1.00 35.36  ? 33  ALA C O   1 
ATOM 2956 C CB  . ALA D 3 34  ? 120.703 105.432 84.824  1.00 35.36  ? 33  ALA C CB  1 
ATOM 2957 N N   . SER D 3 35  ? 117.332 105.858 84.218  1.00 36.07  ? 34  SER C N   1 
ATOM 2958 C CA  . SER D 3 35  ? 116.098 106.584 84.463  1.00 36.07  ? 34  SER C CA  1 
ATOM 2959 C C   . SER D 3 35  ? 115.622 106.399 85.897  1.00 36.07  ? 34  SER C C   1 
ATOM 2960 O O   . SER D 3 35  ? 115.795 105.339 86.501  1.00 36.07  ? 34  SER C O   1 
ATOM 2961 C CB  . SER D 3 35  ? 115.006 106.129 83.495  1.00 36.07  ? 34  SER C CB  1 
ATOM 2962 O OG  . SER D 3 35  ? 115.495 106.080 82.167  1.00 36.07  ? 34  SER C OG  1 
ATOM 2963 N N   . LEU D 3 36  ? 115.018 107.454 86.433  1.00 34.49  ? 35  LEU C N   1 
ATOM 2964 C CA  . LEU D 3 36  ? 114.355 107.427 87.727  1.00 34.49  ? 35  LEU C CA  1 
ATOM 2965 C C   . LEU D 3 36  ? 112.982 108.051 87.555  1.00 34.49  ? 35  LEU C C   1 
ATOM 2966 O O   . LEU D 3 36  ? 112.757 108.843 86.639  1.00 34.49  ? 35  LEU C O   1 
ATOM 2967 C CB  . LEU D 3 36  ? 115.154 108.180 88.793  1.00 34.49  ? 35  LEU C CB  1 
ATOM 2968 C CG  . LEU D 3 36  ? 116.301 107.441 89.474  1.00 34.49  ? 35  LEU C CG  1 
ATOM 2969 C CD1 . LEU D 3 36  ? 117.366 108.426 89.891  1.00 34.49  ? 35  LEU C CD1 1 
ATOM 2970 C CD2 . LEU D 3 36  ? 115.790 106.686 90.677  1.00 34.49  ? 35  LEU C CD2 1 
ATOM 2971 N N   . SER D 3 37  ? 112.055 107.688 88.434  1.00 38.49  ? 36  SER C N   1 
ATOM 2972 C CA  . SER D 3 37  ? 110.684 108.153 88.292  1.00 38.49  ? 36  SER C CA  1 
ATOM 2973 C C   . SER D 3 37  ? 110.032 108.243 89.664  1.00 38.49  ? 36  SER C C   1 
ATOM 2974 O O   . SER D 3 37  ? 110.648 107.945 90.686  1.00 38.49  ? 36  SER C O   1 
ATOM 2975 C CB  . SER D 3 37  ? 109.895 107.232 87.368  1.00 38.49  ? 36  SER C CB  1 
ATOM 2976 O OG  . SER D 3 37  ? 108.513 107.434 87.553  1.00 38.49  ? 36  SER C OG  1 
ATOM 2977 N N   . GLN D 3 38  ? 108.771 108.661 89.680  1.00 43.14  ? 37  GLN C N   1 
ATOM 2978 C CA  . GLN D 3 38  ? 108.011 108.800 90.911  1.00 43.14  ? 37  GLN C CA  1 
ATOM 2979 C C   . GLN D 3 38  ? 106.808 107.871 90.883  1.00 43.14  ? 37  GLN C C   1 
ATOM 2980 O O   . GLN D 3 38  ? 106.218 107.623 89.828  1.00 43.14  ? 37  GLN C O   1 
ATOM 2981 C CB  . GLN D 3 38  ? 107.541 110.241 91.118  1.00 43.14  ? 37  GLN C CB  1 
ATOM 2982 C CG  . GLN D 3 38  ? 107.181 110.569 92.552  1.00 43.14  ? 37  GLN C CG  1 
ATOM 2983 C CD  . GLN D 3 38  ? 106.344 111.823 92.668  1.00 43.14  ? 37  GLN C CD  1 
ATOM 2984 O OE1 . GLN D 3 38  ? 105.832 112.334 91.673  1.00 43.14  ? 37  GLN C OE1 1 
ATOM 2985 N NE2 . GLN D 3 38  ? 106.199 112.328 93.886  1.00 43.14  ? 37  GLN C NE2 1 
ATOM 2986 N N   . ALA D 3 39  ? 106.441 107.363 92.059  1.00 48.25  ? 38  ALA C N   1 
ATOM 2987 C CA  . ALA D 3 39  ? 105.327 106.424 92.187  1.00 48.25  ? 38  ALA C CA  1 
ATOM 2988 C C   . ALA D 3 39  ? 104.016 107.193 92.053  1.00 48.25  ? 38  ALA C C   1 
ATOM 2989 O O   . ALA D 3 39  ? 103.370 107.573 93.032  1.00 48.25  ? 38  ALA C O   1 
ATOM 2990 C CB  . ALA D 3 39  ? 105.405 105.675 93.511  1.00 48.25  ? 38  ALA C CB  1 
ATOM 2991 N N   . GLY D 3 40  ? 103.618 107.425 90.804  1.00 52.55  ? 39  GLY C N   1 
ATOM 2992 C CA  . GLY D 3 40  ? 102.382 108.109 90.507  1.00 52.55  ? 39  GLY C CA  1 
ATOM 2993 C C   . GLY D 3 40  ? 101.261 107.150 90.153  1.00 52.55  ? 39  GLY C C   1 
ATOM 2994 O O   . GLY D 3 40  ? 101.490 106.008 89.763  1.00 52.55  ? 39  GLY C O   1 
ATOM 2995 N N   . ALA D 3 41  ? 100.028 107.638 90.304  1.00 55.53  ? 40  ALA C N   1 
ATOM 2996 C CA  . ALA D 3 41  ? 98.865  106.826 89.961  1.00 55.53  ? 40  ALA C CA  1 
ATOM 2997 C C   . ALA D 3 41  ? 98.793  106.564 88.462  1.00 55.53  ? 40  ALA C C   1 
ATOM 2998 O O   . ALA D 3 41  ? 98.431  105.462 88.035  1.00 55.53  ? 40  ALA C O   1 
ATOM 2999 C CB  . ALA D 3 41  ? 97.587  107.507 90.449  1.00 55.53  ? 40  ALA C CB  1 
ATOM 3000 N N   . VAL D 3 42  ? 99.129  107.557 87.653  1.00 50.38  ? 41  VAL C N   1 
ATOM 3001 C CA  . VAL D 3 42  ? 99.093  107.459 86.196  1.00 50.38  ? 41  VAL C CA  1 
ATOM 3002 C C   . VAL D 3 42  ? 100.527 107.518 85.686  1.00 50.38  ? 41  VAL C C   1 
ATOM 3003 O O   . VAL D 3 42  ? 101.289 108.387 86.123  1.00 50.38  ? 41  VAL C O   1 
ATOM 3004 C CB  . VAL D 3 42  ? 98.248  108.585 85.571  1.00 50.38  ? 41  VAL C CB  1 
ATOM 3005 C CG1 . VAL D 3 42  ? 98.036  108.336 84.090  1.00 50.38  ? 41  VAL C CG1 1 
ATOM 3006 C CG2 . VAL D 3 42  ? 96.919  108.701 86.288  1.00 50.38  ? 41  VAL C CG2 1 
ATOM 3007 N N   . PRO D 3 43  ? 100.938 106.618 84.791  1.00 46.75  ? 42  PRO C N   1 
ATOM 3008 C CA  . PRO D 3 43  ? 102.333 106.629 84.324  1.00 46.75  ? 42  PRO C CA  1 
ATOM 3009 C C   . PRO D 3 43  ? 102.734 107.890 83.579  1.00 46.75  ? 42  PRO C C   1 
ATOM 3010 O O   . PRO D 3 43  ? 103.929 108.203 83.531  1.00 46.75  ? 42  PRO C O   1 
ATOM 3011 C CB  . PRO D 3 43  ? 102.397 105.399 83.409  1.00 46.75  ? 42  PRO C CB  1 
ATOM 3012 C CG  . PRO D 3 43  ? 101.324 104.508 83.927  1.00 46.75  ? 42  PRO C CG  1 
ATOM 3013 C CD  . PRO D 3 43  ? 100.212 105.437 84.303  1.00 46.75  ? 42  PRO C CD  1 
ATOM 3014 N N   . ALA D 3 44  ? 101.789 108.622 82.997  1.00 46.60  ? 43  ALA C N   1 
ATOM 3015 C CA  . ALA D 3 44  ? 102.101 109.792 82.189  1.00 46.60  ? 43  ALA C CA  1 
ATOM 3016 C C   . ALA D 3 44  ? 101.991 111.096 82.966  1.00 46.60  ? 43  ALA C C   1 
ATOM 3017 O O   . ALA D 3 44  ? 102.050 112.169 82.361  1.00 46.60  ? 43  ALA C O   1 
ATOM 3018 C CB  . ALA D 3 44  ? 101.191 109.841 80.962  1.00 46.60  ? 43  ALA C CB  1 
ATOM 3019 N N   . LEU D 3 45  ? 101.830 111.031 84.283  1.00 47.64  ? 44  LEU C N   1 
ATOM 3020 C CA  . LEU D 3 45  ? 101.655 112.214 85.116  1.00 47.64  ? 44  LEU C CA  1 
ATOM 3021 C C   . LEU D 3 45  ? 102.668 112.225 86.242  1.00 47.64  ? 44  LEU C C   1 
ATOM 3022 O O   . LEU D 3 45  ? 102.397 112.700 87.349  1.00 47.64  ? 44  LEU C O   1 
ATOM 3023 C CB  . LEU D 3 45  ? 100.240 112.280 85.676  1.00 47.64  ? 44  LEU C CB  1 
ATOM 3024 C CG  . LEU D 3 45  ? 99.244  112.877 84.693  1.00 47.64  ? 44  LEU C CG  1 
ATOM 3025 C CD1 . LEU D 3 45  ? 97.855  112.898 85.291  1.00 47.64  ? 44  LEU C CD1 1 
ATOM 3026 C CD2 . LEU D 3 45  ? 99.699  114.255 84.295  1.00 47.64  ? 44  LEU C CD2 1 
ATOM 3027 N N   . GLU D 3 46  ? 103.858 111.708 85.972  1.00 43.50  ? 45  GLU C N   1 
ATOM 3028 C CA  . GLU D 3 46  ? 104.844 111.441 87.002  1.00 43.50  ? 45  GLU C CA  1 
ATOM 3029 C C   . GLU D 3 46  ? 106.160 112.123 86.662  1.00 43.50  ? 45  GLU C C   1 
ATOM 3030 O O   . GLU D 3 46  ? 106.557 112.189 85.495  1.00 43.50  ? 45  GLU C O   1 
ATOM 3031 C CB  . GLU D 3 46  ? 105.010 109.924 87.171  1.00 43.50  ? 45  GLU C CB  1 
ATOM 3032 C CG  . GLU D 3 46  ? 106.012 109.271 86.242  1.00 43.50  ? 45  GLU C CG  1 
ATOM 3033 C CD  . GLU D 3 46  ? 105.979 107.760 86.338  1.00 43.50  ? 45  GLU C CD  1 
ATOM 3034 O OE1 . GLU D 3 46  ? 106.714 107.098 85.576  1.00 43.50  ? 45  GLU C OE1 1 
ATOM 3035 O OE2 . GLU D 3 46  ? 105.219 107.233 87.176  1.00 43.50  ? 45  GLU C OE2 1 
ATOM 3036 N N   . LYS D 3 47  ? 106.812 112.661 87.688  1.00 38.19  ? 46  LYS C N   1 
ATOM 3037 C CA  . LYS D 3 47  ? 108.104 113.304 87.519  1.00 38.19  ? 46  LYS C CA  1 
ATOM 3038 C C   . LYS D 3 47  ? 109.190 112.260 87.301  1.00 38.19  ? 46  LYS C C   1 
ATOM 3039 O O   . LYS D 3 47  ? 109.132 111.153 87.837  1.00 38.19  ? 46  LYS C O   1 
ATOM 3040 C CB  . LYS D 3 47  ? 108.432 114.158 88.743  1.00 38.19  ? 46  LYS C CB  1 
ATOM 3041 C CG  . LYS D 3 47  ? 107.241 114.927 89.298  1.00 38.19  ? 46  LYS C CG  1 
ATOM 3042 C CD  . LYS D 3 47  ? 107.547 115.508 90.666  1.00 38.19  ? 46  LYS C CD  1 
ATOM 3043 C CE  . LYS D 3 47  ? 106.847 116.837 90.881  1.00 38.19  ? 46  LYS C CE  1 
ATOM 3044 N NZ  . LYS D 3 47  ? 105.418 116.788 90.483  1.00 38.19  ? 46  LYS C NZ  1 
ATOM 3045 N N   . ARG D 3 48  ? 110.191 112.618 86.499  1.00 35.79  ? 47  ARG C N   1 
ATOM 3046 C CA  . ARG D 3 48  ? 111.258 111.679 86.193  1.00 35.79  ? 47  ARG C CA  1 
ATOM 3047 C C   . ARG D 3 48  ? 112.557 112.429 85.937  1.00 35.79  ? 47  ARG C C   1 
ATOM 3048 O O   . ARG D 3 48  ? 112.552 113.596 85.541  1.00 35.79  ? 47  ARG C O   1 
ATOM 3049 C CB  . ARG D 3 48  ? 110.896 110.799 84.991  1.00 35.79  ? 47  ARG C CB  1 
ATOM 3050 C CG  . ARG D 3 48  ? 110.192 111.526 83.873  1.00 35.79  ? 47  ARG C CG  1 
ATOM 3051 C CD  . ARG D 3 48  ? 109.963 110.614 82.678  1.00 35.79  ? 47  ARG C CD  1 
ATOM 3052 N NE  . ARG D 3 48  ? 109.339 109.354 83.061  1.00 35.79  ? 47  ARG C NE  1 
ATOM 3053 C CZ  . ARG D 3 48  ? 108.088 109.019 82.776  1.00 35.79  ? 47  ARG C CZ  1 
ATOM 3054 N NH1 . ARG D 3 48  ? 107.296 109.825 82.088  1.00 35.79  ? 47  ARG C NH1 1 
ATOM 3055 N NH2 . ARG D 3 48  ? 107.620 107.844 83.188  1.00 35.79  ? 47  ARG C NH2 1 
ATOM 3056 N N   . VAL D 3 49  ? 113.670 111.737 86.173  1.00 30.98  ? 48  VAL C N   1 
ATOM 3057 C CA  . VAL D 3 49  ? 115.013 112.270 85.974  1.00 30.98  ? 48  VAL C CA  1 
ATOM 3058 C C   . VAL D 3 49  ? 115.882 111.171 85.376  1.00 30.98  ? 48  VAL C C   1 
ATOM 3059 O O   . VAL D 3 49  ? 115.707 109.990 85.692  1.00 30.98  ? 48  VAL C O   1 
ATOM 3060 C CB  . VAL D 3 49  ? 115.610 112.807 87.292  1.00 30.98  ? 48  VAL C CB  1 
ATOM 3061 C CG1 . VAL D 3 49  ? 115.780 111.692 88.292  1.00 30.98  ? 48  VAL C CG1 1 
ATOM 3062 C CG2 . VAL D 3 49  ? 116.947 113.464 87.038  1.00 30.98  ? 48  VAL C CG2 1 
ATOM 3063 N N   . THR D 3 50  ? 116.794 111.553 84.482  1.00 31.79  ? 49  THR C N   1 
ATOM 3064 C CA  . THR D 3 50  ? 117.693 110.613 83.821  1.00 31.79  ? 49  THR C CA  1 
ATOM 3065 C C   . THR D 3 50  ? 119.116 111.143 83.910  1.00 31.79  ? 49  THR C C   1 
ATOM 3066 O O   . THR D 3 50  ? 119.360 112.312 83.600  1.00 31.79  ? 49  THR C O   1 
ATOM 3067 C CB  . THR D 3 50  ? 117.306 110.407 82.354  1.00 31.79  ? 49  THR C CB  1 
ATOM 3068 O OG1 . THR D 3 50  ? 117.530 111.620 81.629  1.00 31.79  ? 49  THR C OG1 1 
ATOM 3069 C CG2 . THR D 3 50  ? 115.841 110.022 82.228  1.00 31.79  ? 49  THR C CG2 1 
ATOM 3070 N N   . VAL D 3 51  ? 120.051 110.289 84.319  1.00 30.77  ? 50  VAL C N   1 
ATOM 3071 C CA  . VAL D 3 51  ? 121.466 110.639 84.335  1.00 30.77  ? 50  VAL C CA  1 
ATOM 3072 C C   . VAL D 3 51  ? 122.165 109.860 83.233  1.00 30.77  ? 50  VAL C C   1 
ATOM 3073 O O   . VAL D 3 51  ? 121.718 108.782 82.827  1.00 30.77  ? 50  VAL C O   1 
ATOM 3074 C CB  . VAL D 3 51  ? 122.116 110.368 85.707  1.00 30.77  ? 50  VAL C CB  1 
ATOM 3075 C CG1 . VAL D 3 51  ? 121.331 111.051 86.808  1.00 30.77  ? 50  VAL C CG1 1 
ATOM 3076 C CG2 . VAL D 3 51  ? 122.223 108.882 85.965  1.00 30.77  ? 50  VAL C CG2 1 
ATOM 3077 N N   . SER D 3 52  ? 123.272 110.408 82.733  1.00 33.67  ? 51  SER C N   1 
ATOM 3078 C CA  . SER D 3 52  ? 123.972 109.789 81.608  1.00 33.67  ? 51  SER C CA  1 
ATOM 3079 C C   . SER D 3 52  ? 125.449 110.161 81.693  1.00 33.67  ? 51  SER C C   1 
ATOM 3080 O O   . SER D 3 52  ? 125.836 111.263 81.297  1.00 33.67  ? 51  SER C O   1 
ATOM 3081 C CB  . SER D 3 52  ? 123.367 110.228 80.285  1.00 33.67  ? 51  SER C CB  1 
ATOM 3082 O OG  . SER D 3 52  ? 124.212 109.878 79.206  1.00 33.67  ? 51  SER C OG  1 
ATOM 3083 N N   . VAL D 3 53  ? 126.260 109.237 82.188  1.00 38.14  ? 52  VAL C N   1 
ATOM 3084 C CA  . VAL D 3 53  ? 127.703 109.420 82.272  1.00 38.14  ? 52  VAL C CA  1 
ATOM 3085 C C   . VAL D 3 53  ? 128.351 108.778 81.056  1.00 38.14  ? 52  VAL C C   1 
ATOM 3086 O O   . VAL D 3 53  ? 127.932 107.707 80.605  1.00 38.14  ? 52  VAL C O   1 
ATOM 3087 C CB  . VAL D 3 53  ? 128.254 108.823 83.579  1.00 38.14  ? 52  VAL C CB  1 
ATOM 3088 C CG1 . VAL D 3 53  ? 129.743 109.078 83.694  1.00 38.14  ? 52  VAL C CG1 1 
ATOM 3089 C CG2 . VAL D 3 53  ? 127.523 109.409 84.768  1.00 38.14  ? 52  VAL C CG2 1 
ATOM 3090 N N   . SER D 3 54  ? 129.372 109.438 80.515  1.00 46.73  ? 53  SER C N   1 
ATOM 3091 C CA  . SER D 3 54  ? 130.070 108.918 79.349  1.00 46.73  ? 53  SER C CA  1 
ATOM 3092 C C   . SER D 3 54  ? 130.773 107.607 79.682  1.00 46.73  ? 53  SER C C   1 
ATOM 3093 O O   . SER D 3 54  ? 131.322 107.436 80.773  1.00 46.73  ? 53  SER C O   1 
ATOM 3094 C CB  . SER D 3 54  ? 131.080 109.943 78.838  1.00 46.73  ? 53  SER C CB  1 
ATOM 3095 O OG  . SER D 3 54  ? 131.783 109.445 77.717  1.00 46.73  ? 53  SER C OG  1 
ATOM 3096 N N   . GLN D 3 55  ? 130.755 106.682 78.731  1.00 53.84  ? 54  GLN C N   1 
ATOM 3097 C CA  . GLN D 3 55  ? 131.306 105.353 78.967  1.00 53.84  ? 54  GLN C CA  1 
ATOM 3098 C C   . GLN D 3 55  ? 132.830 105.413 78.950  1.00 53.84  ? 54  GLN C C   1 
ATOM 3099 O O   . GLN D 3 55  ? 133.414 105.912 77.981  1.00 53.84  ? 54  GLN C O   1 
ATOM 3100 C CB  . GLN D 3 55  ? 130.804 104.379 77.905  1.00 53.84  ? 54  GLN C CB  1 
ATOM 3101 C CG  . GLN D 3 55  ? 130.604 102.953 78.390  1.00 53.84  ? 54  GLN C CG  1 
ATOM 3102 C CD  . GLN D 3 55  ? 129.913 102.883 79.737  1.00 53.84  ? 54  GLN C CD  1 
ATOM 3103 O OE1 . GLN D 3 55  ? 128.790 103.360 79.895  1.00 53.84  ? 54  GLN C OE1 1 
ATOM 3104 N NE2 . GLN D 3 55  ? 130.569 102.263 80.709  1.00 53.84  ? 54  GLN C NE2 1 
ATOM 3105 N N   . PRO D 3 56  ? 133.508 104.923 79.990  1.00 58.40  ? 55  PRO C N   1 
ATOM 3106 C CA  . PRO D 3 56  ? 134.975 105.011 80.032  1.00 58.40  ? 55  PRO C CA  1 
ATOM 3107 C C   . PRO D 3 56  ? 135.620 104.091 79.004  1.00 58.40  ? 55  PRO C C   1 
ATOM 3108 O O   . PRO D 3 56  ? 135.293 102.905 78.917  1.00 58.40  ? 55  PRO C O   1 
ATOM 3109 C CB  . PRO D 3 56  ? 135.313 104.572 81.461  1.00 58.40  ? 55  PRO C CB  1 
ATOM 3110 C CG  . PRO D 3 56  ? 134.181 103.687 81.846  1.00 58.40  ? 55  PRO C CG  1 
ATOM 3111 C CD  . PRO D 3 56  ? 132.965 104.305 81.210  1.00 58.40  ? 55  PRO C CD  1 
ATOM 3112 N N   . SER D 3 57  ? 136.549 104.646 78.234  1.00 66.58  ? 56  SER C N   1 
ATOM 3113 C CA  . SER D 3 57  ? 137.294 103.909 77.226  1.00 66.58  ? 56  SER C CA  1 
ATOM 3114 C C   . SER D 3 57  ? 138.779 104.218 77.358  1.00 66.58  ? 56  SER C C   1 
ATOM 3115 O O   . SER D 3 57  ? 139.186 105.147 78.059  1.00 66.58  ? 56  SER C O   1 
ATOM 3116 C CB  . SER D 3 57  ? 136.803 104.251 75.814  1.00 66.58  ? 56  SER C CB  1 
ATOM 3117 O OG  . SER D 3 57  ? 137.543 103.544 74.834  1.00 66.58  ? 56  SER C OG  1 
ATOM 3118 N N   . ARG D 3 58  ? 139.593 103.412 76.673  1.00 71.02  ? 57  ARG C N   1 
ATOM 3119 C CA  . ARG D 3 58  ? 141.039 103.603 76.727  1.00 71.02  ? 57  ARG C CA  1 
ATOM 3120 C C   . ARG D 3 58  ? 141.443 104.945 76.130  1.00 71.02  ? 57  ARG C C   1 
ATOM 3121 O O   . ARG D 3 58  ? 142.323 105.631 76.664  1.00 71.02  ? 57  ARG C O   1 
ATOM 3122 C CB  . ARG D 3 58  ? 141.749 102.458 76.005  1.00 71.02  ? 57  ARG C CB  1 
ATOM 3123 C CG  . ARG D 3 58  ? 141.454 101.083 76.582  1.00 71.02  ? 57  ARG C CG  1 
ATOM 3124 C CD  . ARG D 3 58  ? 142.345 100.019 75.962  1.00 71.02  ? 57  ARG C CD  1 
ATOM 3125 N NE  . ARG D 3 58  ? 142.094 99.849  74.536  1.00 71.02  ? 57  ARG C NE  1 
ATOM 3126 C CZ  . ARG D 3 58  ? 142.823 99.085  73.734  1.00 71.02  ? 57  ARG C CZ  1 
ATOM 3127 N NH1 . ARG D 3 58  ? 143.862 98.403  74.186  1.00 71.02  ? 57  ARG C NH1 1 
ATOM 3128 N NH2 . ARG D 3 58  ? 142.501 99.004  72.446  1.00 71.02  ? 57  ARG C NH2 1 
ATOM 3129 N N   . ASN D 3 59  ? 140.815 105.337 75.025  1.00 67.45  ? 58  ASN C N   1 
ATOM 3130 C CA  . ASN D 3 59  ? 141.107 106.598 74.347  1.00 67.45  ? 58  ASN C CA  1 
ATOM 3131 C C   . ASN D 3 59  ? 139.824 107.426 74.272  1.00 67.45  ? 58  ASN C C   1 
ATOM 3132 O O   . ASN D 3 59  ? 139.104 107.411 73.272  1.00 67.45  ? 58  ASN C O   1 
ATOM 3133 C CB  . ASN D 3 59  ? 141.727 106.335 72.963  1.00 67.45  ? 58  ASN C CB  1 
ATOM 3134 C CG  . ASN D 3 59  ? 140.951 105.311 72.150  1.00 67.45  ? 58  ASN C CG  1 
ATOM 3135 O OD1 . ASN D 3 59  ? 139.917 105.615 71.557  1.00 67.45  ? 58  ASN C OD1 1 
ATOM 3136 N ND2 . ASN D 3 59  ? 141.452 104.082 72.125  1.00 67.45  ? 58  ASN C ND2 1 
ATOM 3137 N N   . ARG D 3 60  ? 139.552 108.168 75.343  1.00 58.00  ? 59  ARG C N   1 
ATOM 3138 C CA  . ARG D 3 60  ? 138.381 109.041 75.428  1.00 58.00  ? 59  ARG C CA  1 
ATOM 3139 C C   . ARG D 3 60  ? 138.871 110.352 76.034  1.00 58.00  ? 59  ARG C C   1 
ATOM 3140 O O   . ARG D 3 60  ? 139.060 110.444 77.250  1.00 58.00  ? 59  ARG C O   1 
ATOM 3141 C CB  . ARG D 3 60  ? 137.276 108.410 76.266  1.00 58.00  ? 59  ARG C CB  1 
ATOM 3142 C CG  . ARG D 3 60  ? 135.951 109.137 76.200  1.00 58.00  ? 59  ARG C CG  1 
ATOM 3143 C CD  . ARG D 3 60  ? 135.367 109.038 74.807  1.00 58.00  ? 59  ARG C CD  1 
ATOM 3144 N NE  . ARG D 3 60  ? 134.075 109.700 74.701  1.00 58.00  ? 59  ARG C NE  1 
ATOM 3145 C CZ  . ARG D 3 60  ? 132.913 109.110 74.941  1.00 58.00  ? 59  ARG C CZ  1 
ATOM 3146 N NH1 . ARG D 3 60  ? 132.846 107.844 75.315  1.00 58.00  ? 59  ARG C NH1 1 
ATOM 3147 N NH2 . ARG D 3 60  ? 131.790 109.809 74.802  1.00 58.00  ? 59  ARG C NH2 1 
ATOM 3148 N N   . LYS D 3 61  ? 139.073 111.363 75.189  1.00 54.38  ? 60  LYS C N   1 
ATOM 3149 C CA  . LYS D 3 61  ? 139.802 112.565 75.589  1.00 54.38  ? 60  LYS C CA  1 
ATOM 3150 C C   . LYS D 3 61  ? 138.818 113.629 76.071  1.00 54.38  ? 60  LYS C C   1 
ATOM 3151 O O   . LYS D 3 61  ? 139.108 114.825 76.081  1.00 54.38  ? 60  LYS C O   1 
ATOM 3152 C CB  . LYS D 3 61  ? 140.661 113.072 74.435  1.00 54.38  ? 60  LYS C CB  1 
ATOM 3153 C CG  . LYS D 3 61  ? 141.557 112.008 73.823  1.00 54.38  ? 60  LYS C CG  1 
ATOM 3154 C CD  . LYS D 3 61  ? 142.371 112.560 72.664  1.00 54.38  ? 60  LYS C CD  1 
ATOM 3155 C CE  . LYS D 3 61  ? 141.704 112.273 71.331  1.00 54.38  ? 60  LYS C CE  1 
ATOM 3156 N NZ  . LYS D 3 61  ? 141.909 113.384 70.361  1.00 54.38  ? 60  LYS C NZ  1 
ATOM 3157 N N   . ASN D 3 62  ? 137.645 113.168 76.506  1.00 51.02  ? 61  ASN C N   1 
ATOM 3158 C CA  . ASN D 3 62  ? 136.657 114.025 77.154  1.00 51.02  ? 61  ASN C CA  1 
ATOM 3159 C C   . ASN D 3 62  ? 135.513 113.212 77.750  1.00 51.02  ? 61  ASN C C   1 
ATOM 3160 O O   . ASN D 3 62  ? 135.146 112.157 77.226  1.00 51.02  ? 61  ASN C O   1 
ATOM 3161 C CB  . ASN D 3 62  ? 136.137 115.093 76.179  1.00 51.02  ? 61  ASN C CB  1 
ATOM 3162 C CG  . ASN D 3 62  ? 135.399 114.512 74.983  1.00 51.02  ? 61  ASN C CG  1 
ATOM 3163 O OD1 . ASN D 3 62  ? 135.145 113.314 74.898  1.00 51.02  ? 61  ASN C OD1 1 
ATOM 3164 N ND2 . ASN D 3 62  ? 135.059 115.380 74.037  1.00 51.02  ? 61  ASN C ND2 1 
ATOM 3165 N N   . TYR D 3 63  ? 134.968 113.681 78.865  1.00 41.80  ? 62  TYR C N   1 
ATOM 3166 C CA  . TYR D 3 63  ? 133.843 113.041 79.526  1.00 41.80  ? 62  TYR C CA  1 
ATOM 3167 C C   . TYR D 3 63  ? 132.698 114.037 79.654  1.00 41.80  ? 62  TYR C C   1 
ATOM 3168 O O   . TYR D 3 63  ? 132.889 115.251 79.580  1.00 41.80  ? 62  TYR C O   1 
ATOM 3169 C CB  . TYR D 3 63  ? 134.248 112.498 80.900  1.00 41.80  ? 62  TYR C CB  1 
ATOM 3170 C CG  . TYR D 3 63  ? 135.176 111.300 80.854  1.00 41.80  ? 62  TYR C CG  1 
ATOM 3171 C CD1 . TYR D 3 63  ? 136.432 111.386 80.273  1.00 41.80  ? 62  TYR C CD1 1 
ATOM 3172 C CD2 . TYR D 3 63  ? 134.786 110.078 81.382  1.00 41.80  ? 62  TYR C CD2 1 
ATOM 3173 C CE1 . TYR D 3 63  ? 137.273 110.297 80.227  1.00 41.80  ? 62  TYR C CE1 1 
ATOM 3174 C CE2 . TYR D 3 63  ? 135.622 108.983 81.339  1.00 41.80  ? 62  TYR C CE2 1 
ATOM 3175 C CZ  . TYR D 3 63  ? 136.863 109.098 80.759  1.00 41.80  ? 62  TYR C CZ  1 
ATOM 3176 O OH  . TYR D 3 63  ? 137.701 108.010 80.714  1.00 41.80  ? 62  TYR C OH  1 
ATOM 3177 N N   . LYS D 3 64  ? 131.491 113.512 79.846  1.00 36.08  ? 63  LYS C N   1 
ATOM 3178 C CA  . LYS D 3 64  ? 130.305 114.362 79.825  1.00 36.08  ? 63  LYS C CA  1 
ATOM 3179 C C   . LYS D 3 64  ? 129.204 113.720 80.655  1.00 36.08  ? 63  LYS C C   1 
ATOM 3180 O O   . LYS D 3 64  ? 128.682 112.665 80.288  1.00 36.08  ? 63  LYS C O   1 
ATOM 3181 C CB  . LYS D 3 64  ? 129.840 114.598 78.393  1.00 36.08  ? 63  LYS C CB  1 
ATOM 3182 C CG  . LYS D 3 64  ? 128.841 115.726 78.249  1.00 36.08  ? 63  LYS C CG  1 
ATOM 3183 C CD  . LYS D 3 64  ? 128.562 116.034 76.788  1.00 36.08  ? 63  LYS C CD  1 
ATOM 3184 C CE  . LYS D 3 64  ? 129.829 115.943 75.950  1.00 36.08  ? 63  LYS C CE  1 
ATOM 3185 N NZ  . LYS D 3 64  ? 130.699 117.139 76.124  1.00 36.08  ? 63  LYS C NZ  1 
ATOM 3186 N N   . VAL D 3 65  ? 128.859 114.359 81.760  1.00 30.58  ? 64  VAL C N   1 
ATOM 3187 C CA  . VAL D 3 65  ? 127.730 113.964 82.591  1.00 30.58  ? 64  VAL C CA  1 
ATOM 3188 C C   . VAL D 3 65  ? 126.539 114.835 82.226  1.00 30.58  ? 64  VAL C C   1 
ATOM 3189 O O   . VAL D 3 65  ? 126.690 116.035 81.979  1.00 30.58  ? 64  VAL C O   1 
ATOM 3190 C CB  . VAL D 3 65  ? 128.082 114.097 84.083  1.00 30.58  ? 64  VAL C CB  1 
ATOM 3191 C CG1 . VAL D 3 65  ? 126.946 113.590 84.947  1.00 30.58  ? 64  VAL C CG1 1 
ATOM 3192 C CG2 . VAL D 3 65  ? 129.364 113.348 84.384  1.00 30.58  ? 64  VAL C CG2 1 
ATOM 3193 N N   . GLN D 3 66  ? 125.349 114.240 82.186  1.00 31.11  ? 65  GLN C N   1 
ATOM 3194 C CA  . GLN D 3 66  ? 124.145 114.972 81.810  1.00 31.11  ? 65  GLN C CA  1 
ATOM 3195 C C   . GLN D 3 66  ? 122.990 114.529 82.692  1.00 31.11  ? 65  GLN C C   1 
ATOM 3196 O O   . GLN D 3 66  ? 122.638 113.348 82.707  1.00 31.11  ? 65  GLN C O   1 
ATOM 3197 C CB  . GLN D 3 66  ? 123.808 114.753 80.335  1.00 31.11  ? 65  GLN C CB  1 
ATOM 3198 C CG  . GLN D 3 66  ? 122.638 115.580 79.850  1.00 31.11  ? 65  GLN C CG  1 
ATOM 3199 C CD  . GLN D 3 66  ? 122.735 115.909 78.378  1.00 31.11  ? 65  GLN C CD  1 
ATOM 3200 O OE1 . GLN D 3 66  ? 123.575 115.364 77.663  1.00 31.11  ? 65  GLN C OE1 1 
ATOM 3201 N NE2 . GLN D 3 66  ? 121.876 116.809 77.915  1.00 31.11  ? 65  GLN C NE2 1 
ATOM 3202 N N   . VAL D 3 67  ? 122.396 115.477 83.412  1.00 28.36  ? 66  VAL C N   1 
ATOM 3203 C CA  . VAL D 3 67  ? 121.260 115.219 84.289  1.00 28.36  ? 66  VAL C CA  1 
ATOM 3204 C C   . VAL D 3 67  ? 120.078 116.014 83.763  1.00 28.36  ? 66  VAL C C   1 
ATOM 3205 O O   . VAL D 3 67  ? 120.190 117.223 83.541  1.00 28.36  ? 66  VAL C O   1 
ATOM 3206 C CB  . VAL D 3 67  ? 121.569 115.601 85.746  1.00 28.36  ? 66  VAL C CB  1 
ATOM 3207 C CG1 . VAL D 3 67  ? 120.417 115.212 86.650  1.00 28.36  ? 66  VAL C CG1 1 
ATOM 3208 C CG2 . VAL D 3 67  ? 122.856 114.950 86.194  1.00 28.36  ? 66  VAL C CG2 1 
ATOM 3209 N N   . LYS D 3 68  ? 118.944 115.346 83.577  1.00 31.03  ? 67  LYS C N   1 
ATOM 3210 C CA  . LYS D 3 68  ? 117.817 115.921 82.847  1.00 31.03  ? 67  LYS C CA  1 
ATOM 3211 C C   . LYS D 3 68  ? 116.526 115.688 83.626  1.00 31.03  ? 67  LYS C C   1 
ATOM 3212 O O   . LYS D 3 68  ? 115.919 114.618 83.530  1.00 31.03  ? 67  LYS C O   1 
ATOM 3213 C CB  . LYS D 3 68  ? 117.743 115.322 81.449  1.00 31.03  ? 67  LYS C CB  1 
ATOM 3214 C CG  . LYS D 3 68  ? 116.668 115.903 80.570  1.00 31.03  ? 67  LYS C CG  1 
ATOM 3215 C CD  . LYS D 3 68  ? 116.867 115.464 79.133  1.00 31.03  ? 67  LYS C CD  1 
ATOM 3216 C CE  . LYS D 3 68  ? 118.319 115.603 78.713  1.00 31.03  ? 67  LYS C CE  1 
ATOM 3217 N NZ  . LYS D 3 68  ? 118.439 115.959 77.274  1.00 31.03  ? 67  LYS C NZ  1 
ATOM 3218 N N   . ILE D 3 69  ? 116.106 116.693 84.385  1.00 30.34  ? 68  ILE C N   1 
ATOM 3219 C CA  . ILE D 3 69  ? 114.858 116.667 85.136  1.00 30.34  ? 68  ILE C CA  1 
ATOM 3220 C C   . ILE D 3 69  ? 113.761 117.240 84.258  1.00 30.34  ? 68  ILE C C   1 
ATOM 3221 O O   . ILE D 3 69  ? 113.971 118.236 83.560  1.00 30.34  ? 68  ILE C O   1 
ATOM 3222 C CB  . ILE D 3 69  ? 114.990 117.479 86.437  1.00 30.34  ? 68  ILE C CB  1 
ATOM 3223 C CG1 . ILE D 3 69  ? 116.086 116.902 87.326  1.00 30.34  ? 68  ILE C CG1 1 
ATOM 3224 C CG2 . ILE D 3 69  ? 113.671 117.520 87.180  1.00 30.34  ? 68  ILE C CG2 1 
ATOM 3225 C CD1 . ILE D 3 69  ? 116.521 117.838 88.419  1.00 30.34  ? 68  ILE C CD1 1 
ATOM 3226 N N   . GLN D 3 70  ? 112.585 116.620 84.279  1.00 33.93  ? 69  GLN C N   1 
ATOM 3227 C CA  . GLN D 3 70  ? 111.431 117.232 83.626  1.00 33.93  ? 69  GLN C CA  1 
ATOM 3228 C C   . GLN D 3 70  ? 110.178 116.715 84.315  1.00 33.93  ? 69  GLN C C   1 
ATOM 3229 O O   . GLN D 3 70  ? 109.982 115.502 84.419  1.00 33.93  ? 69  GLN C O   1 
ATOM 3230 C CB  . GLN D 3 70  ? 111.426 116.956 82.122  1.00 33.93  ? 69  GLN C CB  1 
ATOM 3231 C CG  . GLN D 3 70  ? 111.298 115.524 81.639  1.00 33.93  ? 69  GLN C CG  1 
ATOM 3232 C CD  . GLN D 3 70  ? 109.857 115.069 81.566  1.00 33.93  ? 69  GLN C CD  1 
ATOM 3233 O OE1 . GLN D 3 70  ? 108.956 115.875 81.340  1.00 33.93  ? 69  GLN C OE1 1 
ATOM 3234 N NE2 . GLN D 3 70  ? 109.634 113.773 81.718  1.00 33.93  ? 69  GLN C NE2 1 
ATOM 3235 N N   . ASN D 3 71  ? 109.368 117.634 84.830  1.00 36.35  ? 70  ASN C N   1 
ATOM 3236 C CA  . ASN D 3 71  ? 108.197 117.261 85.603  1.00 36.35  ? 70  ASN C CA  1 
ATOM 3237 C C   . ASN D 3 71  ? 106.938 117.941 85.078  1.00 36.35  ? 70  ASN C C   1 
ATOM 3238 O O   . ASN D 3 71  ? 106.954 119.147 84.794  1.00 36.35  ? 70  ASN C O   1 
ATOM 3239 C CB  . ASN D 3 71  ? 108.417 117.553 87.111  1.00 36.35  ? 70  ASN C CB  1 
ATOM 3240 C CG  . ASN D 3 71  ? 108.762 119.003 87.411  1.00 36.35  ? 70  ASN C CG  1 
ATOM 3241 O OD1 . ASN D 3 71  ? 109.383 119.330 88.414  1.00 36.35  ? 70  ASN C OD1 1 
ATOM 3242 N ND2 . ASN D 3 71  ? 108.342 119.889 86.519  1.00 36.35  ? 70  ASN C ND2 1 
ATOM 3243 N N   . PRO D 3 72  ? 105.858 117.189 84.854  1.00 42.11  ? 71  PRO C N   1 
ATOM 3244 C CA  . PRO D 3 72  ? 104.636 117.786 84.307  1.00 42.11  ? 71  PRO C CA  1 
ATOM 3245 C C   . PRO D 3 72  ? 103.614 118.159 85.366  1.00 42.11  ? 71  PRO C C   1 
ATOM 3246 O O   . PRO D 3 72  ? 103.616 117.597 86.465  1.00 42.11  ? 71  PRO C O   1 
ATOM 3247 C CB  . PRO D 3 72  ? 104.104 116.682 83.390  1.00 42.11  ? 71  PRO C CB  1 
ATOM 3248 C CG  . PRO D 3 72  ? 104.580 115.409 84.030  1.00 42.11  ? 71  PRO C CG  1 
ATOM 3249 C CD  . PRO D 3 72  ? 105.764 115.722 84.919  1.00 42.11  ? 71  PRO C CD  1 
ATOM 3250 N N   . THR D 3 73  ? 102.730 119.100 85.040  1.00 50.52  ? 72  THR C N   1 
ATOM 3251 C CA  . THR D 3 73  ? 101.598 119.444 85.889  1.00 50.52  ? 72  THR C CA  1 
ATOM 3252 C C   . THR D 3 73  ? 100.349 119.494 85.026  1.00 50.52  ? 72  THR C C   1 
ATOM 3253 O O   . THR D 3 73  ? 100.336 120.165 83.990  1.00 50.52  ? 72  THR C O   1 
ATOM 3254 C CB  . THR D 3 73  ? 101.813 120.783 86.595  1.00 50.52  ? 72  THR C CB  1 
ATOM 3255 O OG1 . THR D 3 73  ? 102.361 121.727 85.670  1.00 50.52  ? 72  THR C OG1 1 
ATOM 3256 C CG2 . THR D 3 73  ? 102.767 120.614 87.765  1.00 50.52  ? 72  THR C CG2 1 
ATOM 3257 N N   . ALA D 3 74  ? 99.304  118.788 85.450  1.00 62.55  ? 73  ALA C N   1 
ATOM 3258 C CA  . ALA D 3 74  ? 98.109  118.640 84.634  1.00 62.55  ? 73  ALA C CA  1 
ATOM 3259 C C   . ALA D 3 74  ? 96.856  118.840 85.468  1.00 62.55  ? 73  ALA C C   1 
ATOM 3260 O O   . ALA D 3 74  ? 96.801  118.436 86.633  1.00 62.55  ? 73  ALA C O   1 
ATOM 3261 C CB  . ALA D 3 74  ? 98.057  117.266 83.972  1.00 62.55  ? 73  ALA C CB  1 
ATOM 3262 N N   . CYS D 3 75  ? 95.851  119.454 84.855  1.00 80.66  ? 74  CYS C N   1 
ATOM 3263 C CA  . CYS D 3 75  ? 94.547  119.651 85.465  1.00 80.66  ? 74  CYS C CA  1 
ATOM 3264 C C   . CYS D 3 75  ? 93.512  118.763 84.786  1.00 80.66  ? 74  CYS C C   1 
ATOM 3265 O O   . CYS D 3 75  ? 93.685  118.321 83.648  1.00 80.66  ? 74  CYS C O   1 
ATOM 3266 C CB  . CYS D 3 75  ? 94.116  121.117 85.373  1.00 80.66  ? 74  CYS C CB  1 
ATOM 3267 S SG  . CYS D 3 75  ? 93.673  121.656 83.706  1.00 80.66  ? 74  CYS C SG  1 
ATOM 3268 N N   . THR D 3 76  ? 92.422  118.509 85.506  1.00 92.39  ? 75  THR C N   1 
ATOM 3269 C CA  . THR D 3 76  ? 91.341  117.682 84.987  1.00 92.39  ? 75  THR C CA  1 
ATOM 3270 C C   . THR D 3 76  ? 90.567  118.436 83.914  1.00 92.39  ? 75  THR C C   1 
ATOM 3271 O O   . THR D 3 76  ? 89.693  119.251 84.227  1.00 92.39  ? 75  THR C O   1 
ATOM 3272 C CB  . THR D 3 76  ? 90.403  117.251 86.117  1.00 92.39  ? 75  THR C CB  1 
ATOM 3273 O OG1 . THR D 3 76  ? 89.777  118.407 86.688  1.00 92.39  ? 75  THR C OG1 1 
ATOM 3274 C CG2 . THR D 3 76  ? 91.179  116.517 87.199  1.00 92.39  ? 75  THR C CG2 1 
ATOM 3275 N N   . ALA D 3 77  ? 90.891  118.175 82.650  1.00 98.83  ? 76  ALA C N   1 
ATOM 3276 C CA  . ALA D 3 77  ? 90.253  118.874 81.542  1.00 98.83  ? 76  ALA C CA  1 
ATOM 3277 C C   . ALA D 3 77  ? 88.756  118.608 81.533  1.00 98.83  ? 76  ALA C C   1 
ATOM 3278 O O   . ALA D 3 77  ? 88.317  117.464 81.687  1.00 98.83  ? 76  ALA C O   1 
ATOM 3279 C CB  . ALA D 3 77  ? 90.880  118.439 80.218  1.00 98.83  ? 76  ALA C CB  1 
ATOM 3280 N N   . ASN D 3 78  ? 87.972  119.668 81.357  1.00 103.38 ? 77  ASN C N   1 
ATOM 3281 C CA  . ASN D 3 78  ? 86.525  119.525 81.316  1.00 103.38 ? 77  ASN C CA  1 
ATOM 3282 C C   . ASN D 3 78  ? 86.099  118.742 80.079  1.00 103.38 ? 77  ASN C C   1 
ATOM 3283 O O   . ASN D 3 78  ? 86.719  118.827 79.016  1.00 103.38 ? 77  ASN C O   1 
ATOM 3284 C CB  . ASN D 3 78  ? 85.852  120.899 81.326  1.00 103.38 ? 77  ASN C CB  1 
ATOM 3285 C CG  . ASN D 3 78  ? 85.955  121.588 82.673  1.00 103.38 ? 77  ASN C CG  1 
ATOM 3286 O OD1 . ASN D 3 78  ? 85.746  120.970 83.717  1.00 103.38 ? 77  ASN C OD1 1 
ATOM 3287 N ND2 . ASN D 3 78  ? 86.278  122.876 82.655  1.00 103.38 ? 77  ASN C ND2 1 
ATOM 3288 N N   . GLY D 3 79  ? 85.028  117.968 80.231  1.00 104.51 ? 78  GLY C N   1 
ATOM 3289 C CA  . GLY D 3 79  ? 84.501  117.182 79.136  1.00 104.51 ? 78  GLY C CA  1 
ATOM 3290 C C   . GLY D 3 79  ? 85.187  115.857 78.902  1.00 104.51 ? 78  GLY C C   1 
ATOM 3291 O O   . GLY D 3 79  ? 84.840  115.162 77.940  1.00 104.51 ? 78  GLY C O   1 
ATOM 3292 N N   . SER D 3 80  ? 86.149  115.482 79.743  1.00 102.34 ? 79  SER C N   1 
ATOM 3293 C CA  . SER D 3 80  ? 86.822  114.200 79.605  1.00 102.34 ? 79  SER C CA  1 
ATOM 3294 C C   . SER D 3 80  ? 87.018  113.597 80.987  1.00 102.34 ? 79  SER C C   1 
ATOM 3295 O O   . SER D 3 80  ? 87.057  114.304 81.996  1.00 102.34 ? 79  SER C O   1 
ATOM 3296 C CB  . SER D 3 80  ? 88.167  114.339 78.882  1.00 102.34 ? 79  SER C CB  1 
ATOM 3297 O OG  . SER D 3 80  ? 88.801  113.080 78.750  1.00 102.34 ? 79  SER C OG  1 
ATOM 3298 N N   . CYS D 3 81  ? 87.136  112.271 81.019  1.00 98.18  ? 80  CYS C N   1 
ATOM 3299 C CA  . CYS D 3 81  ? 87.272  111.549 82.276  1.00 98.18  ? 80  CYS C CA  1 
ATOM 3300 C C   . CYS D 3 81  ? 88.719  111.343 82.699  1.00 98.18  ? 80  CYS C C   1 
ATOM 3301 O O   . CYS D 3 81  ? 88.966  111.027 83.869  1.00 98.18  ? 80  CYS C O   1 
ATOM 3302 C CB  . CYS D 3 81  ? 86.576  110.188 82.180  1.00 98.18  ? 80  CYS C CB  1 
ATOM 3303 S SG  . CYS D 3 81  ? 87.300  109.067 80.961  1.00 98.18  ? 80  CYS C SG  1 
ATOM 3304 N N   . ASP D 3 82  ? 89.680  111.515 81.788  1.00 88.52  ? 81  ASP C N   1 
ATOM 3305 C CA  . ASP D 3 82  ? 91.069  111.299 82.155  1.00 88.52  ? 81  ASP C CA  1 
ATOM 3306 C C   . ASP D 3 82  ? 91.859  112.601 82.090  1.00 88.52  ? 81  ASP C C   1 
ATOM 3307 O O   . ASP D 3 82  ? 91.646  113.413 81.183  1.00 88.52  ? 81  ASP C O   1 
ATOM 3308 C CB  . ASP D 3 82  ? 91.724  110.256 81.240  1.00 88.52  ? 81  ASP C CB  1 
ATOM 3309 C CG  . ASP D 3 82  ? 91.638  110.626 79.771  1.00 88.52  ? 81  ASP C CG  1 
ATOM 3310 O OD1 . ASP D 3 82  ? 92.392  111.518 79.328  1.00 88.52  ? 81  ASP C OD1 1 
ATOM 3311 O OD2 . ASP D 3 82  ? 90.811  110.023 79.057  1.00 88.52  ? 81  ASP C OD2 1 
ATOM 3312 N N   . PRO D 3 83  ? 92.760  112.833 83.042  1.00 76.91  ? 82  PRO C N   1 
ATOM 3313 C CA  . PRO D 3 83  ? 93.575  114.051 83.004  1.00 76.91  ? 82  PRO C CA  1 
ATOM 3314 C C   . PRO D 3 83  ? 94.570  114.024 81.856  1.00 76.91  ? 82  PRO C C   1 
ATOM 3315 O O   . PRO D 3 83  ? 95.016  112.965 81.411  1.00 76.91  ? 82  PRO C O   1 
ATOM 3316 C CB  . PRO D 3 83  ? 94.286  114.039 84.360  1.00 76.91  ? 82  PRO C CB  1 
ATOM 3317 C CG  . PRO D 3 83  ? 94.347  112.594 84.721  1.00 76.91  ? 82  PRO C CG  1 
ATOM 3318 C CD  . PRO D 3 83  ? 93.063  112.004 84.220  1.00 76.91  ? 82  PRO C CD  1 
ATOM 3319 N N   . SER D 3 84  ? 94.919  115.216 81.379  1.00 67.41  ? 83  SER C N   1 
ATOM 3320 C CA  . SER D 3 84  ? 95.851  115.371 80.274  1.00 67.41  ? 83  SER C CA  1 
ATOM 3321 C C   . SER D 3 84  ? 96.885  116.429 80.625  1.00 67.41  ? 83  SER C C   1 
ATOM 3322 O O   . SER D 3 84  ? 96.573  117.435 81.267  1.00 67.41  ? 83  SER C O   1 
ATOM 3323 C CB  . SER D 3 84  ? 95.130  115.756 78.978  1.00 67.41  ? 83  SER C CB  1 
ATOM 3324 O OG  . SER D 3 84  ? 95.977  115.588 77.855  1.00 67.41  ? 83  SER C OG  1 
ATOM 3325 N N   . VAL D 3 85  ? 98.119  116.199 80.179  1.00 58.50  ? 84  VAL C N   1 
ATOM 3326 C CA  . VAL D 3 85  ? 99.226  117.087 80.513  1.00 58.50  ? 84  VAL C CA  1 
ATOM 3327 C C   . VAL D 3 85  ? 99.025  118.425 79.815  1.00 58.50  ? 84  VAL C C   1 
ATOM 3328 O O   . VAL D 3 85  ? 98.899  118.491 78.587  1.00 58.50  ? 84  VAL C O   1 
ATOM 3329 C CB  . VAL D 3 85  ? 100.568 116.458 80.123  1.00 58.50  ? 84  VAL C CB  1 
ATOM 3330 C CG1 . VAL D 3 85  ? 101.687 117.472 80.262  1.00 58.50  ? 84  VAL C CG1 1 
ATOM 3331 C CG2 . VAL D 3 85  ? 100.843 115.237 80.977  1.00 58.50  ? 84  VAL C CG2 1 
ATOM 3332 N N   . THR D 3 86  ? 98.997  119.501 80.599  1.00 55.36  ? 85  THR C N   1 
ATOM 3333 C CA  . THR D 3 86  ? 98.866  120.844 80.052  1.00 55.36  ? 85  THR C CA  1 
ATOM 3334 C C   . THR D 3 86  ? 100.216 121.518 79.851  1.00 55.36  ? 85  THR C C   1 
ATOM 3335 O O   . THR D 3 86  ? 100.413 122.223 78.857  1.00 55.36  ? 85  THR C O   1 
ATOM 3336 C CB  . THR D 3 86  ? 97.990  121.702 80.967  1.00 55.36  ? 85  THR C CB  1 
ATOM 3337 O OG1 . THR D 3 86  ? 98.603  121.805 82.257  1.00 55.36  ? 85  THR C OG1 1 
ATOM 3338 C CG2 . THR D 3 86  ? 96.616  121.082 81.118  1.00 55.36  ? 85  THR C CG2 1 
ATOM 3339 N N   . ARG D 3 87  ? 101.151 121.313 80.775  1.00 47.73  ? 86  ARG C N   1 
ATOM 3340 C CA  . ARG D 3 87  ? 102.463 121.935 80.687  1.00 47.73  ? 86  ARG C CA  1 
ATOM 3341 C C   . ARG D 3 87  ? 103.435 121.153 81.555  1.00 47.73  ? 86  ARG C C   1 
ATOM 3342 O O   . ARG D 3 87  ? 103.035 120.366 82.417  1.00 47.73  ? 86  ARG C O   1 
ATOM 3343 C CB  . ARG D 3 87  ? 102.417 123.400 81.123  1.00 47.73  ? 86  ARG C CB  1 
ATOM 3344 C CG  . ARG D 3 87  ? 101.971 123.579 82.554  1.00 47.73  ? 86  ARG C CG  1 
ATOM 3345 C CD  . ARG D 3 87  ? 102.012 125.028 82.980  1.00 47.73  ? 86  ARG C CD  1 
ATOM 3346 N NE  . ARG D 3 87  ? 101.823 125.153 84.419  1.00 47.73  ? 86  ARG C NE  1 
ATOM 3347 C CZ  . ARG D 3 87  ? 100.640 125.179 85.015  1.00 47.73  ? 86  ARG C CZ  1 
ATOM 3348 N NH1 . ARG D 3 87  ? 99.516  125.120 84.322  1.00 47.73  ? 86  ARG C NH1 1 
ATOM 3349 N NH2 . ARG D 3 87  ? 100.585 125.269 86.340  1.00 47.73  ? 86  ARG C NH2 1 
ATOM 3350 N N   . GLN D 3 88  ? 104.723 121.385 81.314  1.00 42.26  ? 87  GLN C N   1 
ATOM 3351 C CA  . GLN D 3 88  ? 105.766 120.721 82.077  1.00 42.26  ? 87  GLN C CA  1 
ATOM 3352 C C   . GLN D 3 88  ? 107.000 121.608 82.124  1.00 42.26  ? 87  GLN C C   1 
ATOM 3353 O O   . GLN D 3 88  ? 107.213 122.459 81.258  1.00 42.26  ? 87  GLN C O   1 
ATOM 3354 C CB  . GLN D 3 88  ? 106.094 119.347 81.486  1.00 42.26  ? 87  GLN C CB  1 
ATOM 3355 C CG  . GLN D 3 88  ? 106.116 119.307 79.977  1.00 42.26  ? 87  GLN C CG  1 
ATOM 3356 C CD  . GLN D 3 88  ? 106.111 117.892 79.451  1.00 42.26  ? 87  GLN C CD  1 
ATOM 3357 O OE1 . GLN D 3 88  ? 106.114 116.934 80.222  1.00 42.26  ? 87  GLN C OE1 1 
ATOM 3358 N NE2 . GLN D 3 88  ? 106.093 117.749 78.132  1.00 42.26  ? 87  GLN C NE2 1 
ATOM 3359 N N   . ALA D 3 89  ? 107.812 121.394 83.154  1.00 36.88  ? 88  ALA C N   1 
ATOM 3360 C CA  . ALA D 3 89  ? 109.013 122.182 83.392  1.00 36.88  ? 88  ALA C CA  1 
ATOM 3361 C C   . ALA D 3 89  ? 110.242 121.312 83.176  1.00 36.88  ? 88  ALA C C   1 
ATOM 3362 O O   . ALA D 3 89  ? 110.306 120.185 83.681  1.00 36.88  ? 88  ALA C O   1 
ATOM 3363 C CB  . ALA D 3 89  ? 109.016 122.763 84.805  1.00 36.88  ? 88  ALA C CB  1 
ATOM 3364 N N   . TYR D 3 90  ? 111.210 121.844 82.435  1.00 34.51  ? 89  TYR C N   1 
ATOM 3365 C CA  . TYR D 3 90  ? 112.432 121.149 82.065  1.00 34.51  ? 89  TYR C CA  1 
ATOM 3366 C C   . TYR D 3 90  ? 113.626 121.775 82.773  1.00 34.51  ? 89  TYR C C   1 
ATOM 3367 O O   . TYR D 3 90  ? 113.610 122.953 83.136  1.00 34.51  ? 89  TYR C O   1 
ATOM 3368 C CB  . TYR D 3 90  ? 112.666 121.216 80.553  1.00 34.51  ? 89  TYR C CB  1 
ATOM 3369 C CG  . TYR D 3 90  ? 111.545 120.683 79.697  1.00 34.51  ? 89  TYR C CG  1 
ATOM 3370 C CD1 . TYR D 3 90  ? 111.128 119.369 79.800  1.00 34.51  ? 89  TYR C CD1 1 
ATOM 3371 C CD2 . TYR D 3 90  ? 110.911 121.498 78.773  1.00 34.51  ? 89  TYR C CD2 1 
ATOM 3372 C CE1 . TYR D 3 90  ? 110.110 118.881 79.011  1.00 34.51  ? 89  TYR C CE1 1 
ATOM 3373 C CE2 . TYR D 3 90  ? 109.893 121.022 77.982  1.00 34.51  ? 89  TYR C CE2 1 
ATOM 3374 C CZ  . TYR D 3 90  ? 109.495 119.712 78.104  1.00 34.51  ? 89  TYR C CZ  1 
ATOM 3375 O OH  . TYR D 3 90  ? 108.476 119.233 77.315  1.00 34.51  ? 89  TYR C OH  1 
ATOM 3376 N N   . ALA D 3 91  ? 114.673 120.971 82.957  1.00 30.09  ? 90  ALA C N   1 
ATOM 3377 C CA  . ALA D 3 91  ? 115.943 121.457 83.480  1.00 30.09  ? 90  ALA C CA  1 
ATOM 3378 C C   . ALA D 3 91  ? 117.051 120.449 83.212  1.00 30.09  ? 90  ALA C C   1 
ATOM 3379 O O   . ALA D 3 91  ? 117.025 119.347 83.760  1.00 30.09  ? 90  ALA C O   1 
ATOM 3380 C CB  . ALA D 3 91  ? 115.838 121.730 84.980  1.00 30.09  ? 90  ALA C CB  1 
ATOM 3381 N N   . ASP D 3 92  ? 118.038 120.803 82.396  1.00 31.80  ? 91  ASP C N   1 
ATOM 3382 C CA  . ASP D 3 92  ? 119.135 119.890 82.110  1.00 31.80  ? 91  ASP C CA  1 
ATOM 3383 C C   . ASP D 3 92  ? 120.479 120.551 82.382  1.00 31.80  ? 91  ASP C C   1 
ATOM 3384 O O   . ASP D 3 92  ? 120.678 121.738 82.116  1.00 31.80  ? 91  ASP C O   1 
ATOM 3385 C CB  . ASP D 3 92  ? 119.060 119.346 80.667  1.00 31.80  ? 91  ASP C CB  1 
ATOM 3386 C CG  . ASP D 3 92  ? 119.185 120.424 79.607  1.00 31.80  ? 91  ASP C CG  1 
ATOM 3387 O OD1 . ASP D 3 92  ? 119.288 121.617 79.945  1.00 31.80  ? 91  ASP C OD1 1 
ATOM 3388 O OD2 . ASP D 3 92  ? 119.179 120.068 78.410  1.00 31.80  ? 91  ASP C OD2 1 
ATOM 3389 N N   . VAL D 3 93  ? 121.392 119.768 82.947  1.00 28.46  ? 92  VAL C N   1 
ATOM 3390 C CA  . VAL D 3 93  ? 122.735 120.228 83.278  1.00 28.46  ? 92  VAL C CA  1 
ATOM 3391 C C   . VAL D 3 93  ? 123.744 119.273 82.658  1.00 28.46  ? 92  VAL C C   1 
ATOM 3392 O O   . VAL D 3 93  ? 123.592 118.050 82.740  1.00 28.46  ? 92  VAL C O   1 
ATOM 3393 C CB  . VAL D 3 93  ? 122.931 120.360 84.804  1.00 28.46  ? 92  VAL C CB  1 
ATOM 3394 C CG1 . VAL D 3 93  ? 122.693 119.044 85.501  1.00 28.46  ? 92  VAL C CG1 1 
ATOM 3395 C CG2 . VAL D 3 93  ? 124.321 120.872 85.113  1.00 28.46  ? 92  VAL C CG2 1 
ATOM 3396 N N   . THR D 3 94  ? 124.760 119.836 82.004  1.00 29.33  ? 93  THR C N   1 
ATOM 3397 C CA  . THR D 3 94  ? 125.751 119.060 81.259  1.00 29.33  ? 93  THR C CA  1 
ATOM 3398 C C   . THR D 3 94  ? 127.149 119.458 81.722  1.00 29.33  ? 93  THR C C   1 
ATOM 3399 O O   . THR D 3 94  ? 127.658 120.512 81.335  1.00 29.33  ? 93  THR C O   1 
ATOM 3400 C CB  . THR D 3 94  ? 125.610 119.278 79.757  1.00 29.33  ? 93  THR C CB  1 
ATOM 3401 O OG1 . THR D 3 94  ? 126.080 120.588 79.421  1.00 29.33  ? 93  THR C OG1 1 
ATOM 3402 C CG2 . THR D 3 94  ? 124.159 119.145 79.324  1.00 29.33  ? 93  THR C CG2 1 
ATOM 3403 N N   . PHE D 3 95  ? 127.770 118.614 82.539  1.00 28.24  ? 94  PHE C N   1 
ATOM 3404 C CA  . PHE D 3 95  ? 129.168 118.798 82.890  1.00 28.24  ? 94  PHE C CA  1 
ATOM 3405 C C   . PHE D 3 95  ? 130.059 118.252 81.782  1.00 28.24  ? 94  PHE C C   1 
ATOM 3406 O O   . PHE D 3 95  ? 129.714 117.282 81.106  1.00 28.24  ? 94  PHE C O   1 
ATOM 3407 C CB  . PHE D 3 95  ? 129.491 118.099 84.206  1.00 28.24  ? 94  PHE C CB  1 
ATOM 3408 C CG  . PHE D 3 95  ? 128.692 118.599 85.368  1.00 28.24  ? 94  PHE C CG  1 
ATOM 3409 C CD1 . PHE D 3 95  ? 129.126 119.680 86.108  1.00 28.24  ? 94  PHE C CD1 1 
ATOM 3410 C CD2 . PHE D 3 95  ? 127.509 117.985 85.725  1.00 28.24  ? 94  PHE C CD2 1 
ATOM 3411 C CE1 . PHE D 3 95  ? 128.395 120.139 87.178  1.00 28.24  ? 94  PHE C CE1 1 
ATOM 3412 C CE2 . PHE D 3 95  ? 126.775 118.441 86.797  1.00 28.24  ? 94  PHE C CE2 1 
ATOM 3413 C CZ  . PHE D 3 95  ? 127.219 119.521 87.522  1.00 28.24  ? 94  PHE C CZ  1 
ATOM 3414 N N   . SER D 3 96  ? 131.216 118.884 81.600  1.00 31.71  ? 95  SER C N   1 
ATOM 3415 C CA  . SER D 3 96  ? 132.142 118.504 80.533  1.00 31.71  ? 95  SER C CA  1 
ATOM 3416 C C   . SER D 3 96  ? 133.566 118.655 81.054  1.00 31.71  ? 95  SER C C   1 
ATOM 3417 O O   . SER D 3 96  ? 134.119 119.758 81.051  1.00 31.71  ? 95  SER C O   1 
ATOM 3418 C CB  . SER D 3 96  ? 131.920 119.349 79.286  1.00 31.71  ? 95  SER C CB  1 
ATOM 3419 O OG  . SER D 3 96  ? 132.842 118.998 78.269  1.00 31.71  ? 95  SER C OG  1 
ATOM 3420 N N   . PHE D 3 97  ? 134.158 117.548 81.487  1.00 35.88  ? 96  PHE C N   1 
ATOM 3421 C CA  . PHE D 3 97  ? 135.507 117.542 82.020  1.00 35.88  ? 96  PHE C CA  1 
ATOM 3422 C C   . PHE D 3 97  ? 136.496 117.081 80.955  1.00 35.88  ? 96  PHE C C   1 
ATOM 3423 O O   . PHE D 3 97  ? 136.146 116.842 79.798  1.00 35.88  ? 96  PHE C O   1 
ATOM 3424 C CB  . PHE D 3 97  ? 135.580 116.659 83.263  1.00 35.88  ? 96  PHE C CB  1 
ATOM 3425 C CG  . PHE D 3 97  ? 134.494 116.931 84.253  1.00 35.88  ? 96  PHE C CG  1 
ATOM 3426 C CD1 . PHE D 3 97  ? 134.451 118.131 84.935  1.00 35.88  ? 96  PHE C CD1 1 
ATOM 3427 C CD2 . PHE D 3 97  ? 133.510 115.993 84.494  1.00 35.88  ? 96  PHE C CD2 1 
ATOM 3428 C CE1 . PHE D 3 97  ? 133.450 118.388 85.843  1.00 35.88  ? 96  PHE C CE1 1 
ATOM 3429 C CE2 . PHE D 3 97  ? 132.508 116.245 85.404  1.00 35.88  ? 96  PHE C CE2 1 
ATOM 3430 C CZ  . PHE D 3 97  ? 132.478 117.444 86.078  1.00 35.88  ? 96  PHE C CZ  1 
ATOM 3431 N N   . THR D 3 98  ? 137.754 116.960 81.359  1.00 39.81  ? 97  THR C N   1 
ATOM 3432 C CA  . THR D 3 98  ? 138.848 116.603 80.473  1.00 39.81  ? 97  THR C CA  1 
ATOM 3433 C C   . THR D 3 98  ? 139.421 115.259 80.906  1.00 39.81  ? 97  THR C C   1 
ATOM 3434 O O   . THR D 3 98  ? 139.226 114.812 82.039  1.00 39.81  ? 97  THR C O   1 
ATOM 3435 C CB  . THR D 3 98  ? 139.925 117.699 80.489  1.00 39.81  ? 97  THR C CB  1 
ATOM 3436 O OG1 . THR D 3 98  ? 139.322 118.952 80.150  1.00 39.81  ? 97  THR C OG1 1 
ATOM 3437 C CG2 . THR D 3 98  ? 141.025 117.428 79.473  1.00 39.81  ? 97  THR C CG2 1 
ATOM 3438 N N   . GLN D 3 99  ? 140.125 114.608 79.980  1.00 44.38  ? 98  GLN C N   1 
ATOM 3439 C CA  . GLN D 3 99  ? 140.736 113.313 80.251  1.00 44.38  ? 98  GLN C CA  1 
ATOM 3440 C C   . GLN D 3 99  ? 141.726 113.361 81.408  1.00 44.38  ? 98  GLN C C   1 
ATOM 3441 O O   . GLN D 3 99  ? 142.001 112.321 82.014  1.00 44.38  ? 98  GLN C O   1 
ATOM 3442 C CB  . GLN D 3 99  ? 141.435 112.818 78.986  1.00 44.38  ? 98  GLN C CB  1 
ATOM 3443 C CG  . GLN D 3 99  ? 141.852 111.369 79.001  1.00 44.38  ? 98  GLN C CG  1 
ATOM 3444 C CD  . GLN D 3 99  ? 142.814 111.048 77.878  1.00 44.38  ? 98  GLN C CD  1 
ATOM 3445 O OE1 . GLN D 3 99  ? 143.580 111.906 77.439  1.00 44.38  ? 98  GLN C OE1 1 
ATOM 3446 N NE2 . GLN D 3 99  ? 142.781 109.809 77.404  1.00 44.38  ? 98  GLN C NE2 1 
ATOM 3447 N N   . TYR D 3 100 ? 142.261 114.537 81.733  1.00 41.60  ? 99  TYR C N   1 
ATOM 3448 C CA  . TYR D 3 100 ? 143.283 114.680 82.762  1.00 41.60  ? 99  TYR C CA  1 
ATOM 3449 C C   . TYR D 3 100 ? 142.765 115.340 84.033  1.00 41.60  ? 99  TYR C C   1 
ATOM 3450 O O   . TYR D 3 100 ? 143.557 115.615 84.938  1.00 41.60  ? 99  TYR C O   1 
ATOM 3451 C CB  . TYR D 3 100 ? 144.466 115.478 82.215  1.00 41.60  ? 99  TYR C CB  1 
ATOM 3452 C CG  . TYR D 3 100 ? 145.368 114.689 81.299  1.00 41.60  ? 99  TYR C CG  1 
ATOM 3453 C CD1 . TYR D 3 100 ? 146.174 113.676 81.793  1.00 41.60  ? 99  TYR C CD1 1 
ATOM 3454 C CD2 . TYR D 3 100 ? 145.414 114.958 79.940  1.00 41.60  ? 99  TYR C CD2 1 
ATOM 3455 C CE1 . TYR D 3 100 ? 146.999 112.953 80.960  1.00 41.60  ? 99  TYR C CE1 1 
ATOM 3456 C CE2 . TYR D 3 100 ? 146.237 114.240 79.100  1.00 41.60  ? 99  TYR C CE2 1 
ATOM 3457 C CZ  . TYR D 3 100 ? 147.026 113.238 79.615  1.00 41.60  ? 99  TYR C CZ  1 
ATOM 3458 O OH  . TYR D 3 100 ? 147.848 112.518 78.781  1.00 41.60  ? 99  TYR C OH  1 
ATOM 3459 N N   . SER D 3 101 ? 141.464 115.599 84.129  1.00 42.78  ? 100 SER C N   1 
ATOM 3460 C CA  . SER D 3 101 ? 140.928 116.311 85.281  1.00 42.78  ? 100 SER C CA  1 
ATOM 3461 C C   . SER D 3 101 ? 140.910 115.413 86.510  1.00 42.78  ? 100 SER C C   1 
ATOM 3462 O O   . SER D 3 101 ? 140.461 114.265 86.448  1.00 42.78  ? 100 SER C O   1 
ATOM 3463 C CB  . SER D 3 101 ? 139.520 116.818 84.980  1.00 42.78  ? 100 SER C CB  1 
ATOM 3464 O OG  . SER D 3 101 ? 139.561 118.046 84.276  1.00 42.78  ? 100 SER C OG  1 
ATOM 3465 N N   . THR D 3 102 ? 141.390 115.944 87.631  1.00 44.70  ? 101 THR C N   1 
ATOM 3466 C CA  . THR D 3 102 ? 141.411 115.206 88.883  1.00 44.70  ? 101 THR C CA  1 
ATOM 3467 C C   . THR D 3 102 ? 140.060 115.314 89.587  1.00 44.70  ? 101 THR C C   1 
ATOM 3468 O O   . THR D 3 102 ? 139.123 115.953 89.103  1.00 44.70  ? 101 THR C O   1 
ATOM 3469 C CB  . THR D 3 102 ? 142.534 115.715 89.781  1.00 44.70  ? 101 THR C CB  1 
ATOM 3470 O OG1 . THR D 3 102 ? 142.281 117.077 90.140  1.00 44.70  ? 101 THR C OG1 1 
ATOM 3471 C CG2 . THR D 3 102 ? 143.867 115.630 89.059  1.00 44.70  ? 101 THR C CG2 1 
ATOM 3472 N N   . ASP D 3 103 ? 139.956 114.672 90.751  1.00 44.94  ? 102 ASP C N   1 
ATOM 3473 C CA  . ASP D 3 103 ? 138.703 114.680 91.498  1.00 44.94  ? 102 ASP C CA  1 
ATOM 3474 C C   . ASP D 3 103 ? 138.445 116.028 92.161  1.00 44.94  ? 102 ASP C C   1 
ATOM 3475 O O   . ASP D 3 103 ? 137.284 116.440 92.301  1.00 44.94  ? 102 ASP C O   1 
ATOM 3476 C CB  . ASP D 3 103 ? 138.721 113.569 92.546  1.00 44.94  ? 102 ASP C CB  1 
ATOM 3477 C CG  . ASP D 3 103 ? 137.344 113.248 93.078  1.00 44.94  ? 102 ASP C CG  1 
ATOM 3478 O OD1 . ASP D 3 103 ? 136.361 113.841 92.589  1.00 44.94  ? 102 ASP C OD1 1 
ATOM 3479 O OD2 . ASP D 3 103 ? 137.242 112.400 93.990  1.00 44.94  ? 102 ASP C OD2 1 
ATOM 3480 N N   . GLU D 3 104 ? 139.508 116.721 92.575  1.00 44.70  ? 103 GLU C N   1 
ATOM 3481 C CA  . GLU D 3 104 ? 139.367 118.011 93.240  1.00 44.70  ? 103 GLU C CA  1 
ATOM 3482 C C   . GLU D 3 104 ? 138.720 119.057 92.347  1.00 44.70  ? 103 GLU C C   1 
ATOM 3483 O O   . GLU D 3 104 ? 138.161 120.029 92.860  1.00 44.70  ? 103 GLU C O   1 
ATOM 3484 C CB  . GLU D 3 104 ? 140.735 118.518 93.702  1.00 44.70  ? 103 GLU C CB  1 
ATOM 3485 C CG  . GLU D 3 104 ? 141.679 117.456 94.259  1.00 44.70  ? 103 GLU C CG  1 
ATOM 3486 C CD  . GLU D 3 104 ? 141.023 116.517 95.253  1.00 44.70  ? 103 GLU C CD  1 
ATOM 3487 O OE1 . GLU D 3 104 ? 141.435 115.340 95.315  1.00 44.70  ? 103 GLU C OE1 1 
ATOM 3488 O OE2 . GLU D 3 104 ? 140.128 116.960 96.000  1.00 44.70  ? 103 GLU C OE2 1 
ATOM 3489 N N   . GLU D 3 105 ? 138.791 118.885 91.030  1.00 43.99  ? 104 GLU C N   1 
ATOM 3490 C CA  . GLU D 3 105 ? 138.174 119.815 90.096  1.00 43.99  ? 104 GLU C CA  1 
ATOM 3491 C C   . GLU D 3 105 ? 136.702 119.503 89.876  1.00 43.99  ? 104 GLU C C   1 
ATOM 3492 O O   . GLU D 3 105 ? 135.862 120.412 89.885  1.00 43.99  ? 104 GLU C O   1 
ATOM 3493 C CB  . GLU D 3 105 ? 138.918 119.775 88.761  1.00 43.99  ? 104 GLU C CB  1 
ATOM 3494 C CG  . GLU D 3 105 ? 140.404 120.045 88.884  1.00 43.99  ? 104 GLU C CG  1 
ATOM 3495 C CD  . GLU D 3 105 ? 141.069 120.261 87.542  1.00 43.99  ? 104 GLU C CD  1 
ATOM 3496 O OE1 . GLU D 3 105 ? 140.357 120.590 86.570  1.00 43.99  ? 104 GLU C OE1 1 
ATOM 3497 O OE2 . GLU D 3 105 ? 142.304 120.097 87.458  1.00 43.99  ? 104 GLU C OE2 1 
ATOM 3498 N N   . ARG D 3 106 ? 136.375 118.226 89.684  1.00 38.55  ? 105 ARG C N   1 
ATOM 3499 C CA  . ARG D 3 106 ? 134.992 117.839 89.445  1.00 38.55  ? 105 ARG C CA  1 
ATOM 3500 C C   . ARG D 3 106 ? 134.129 118.069 90.680  1.00 38.55  ? 105 ARG C C   1 
ATOM 3501 O O   . ARG D 3 106 ? 133.004 118.579 90.574  1.00 38.55  ? 105 ARG C O   1 
ATOM 3502 C CB  . ARG D 3 106 ? 134.945 116.381 88.996  1.00 38.55  ? 105 ARG C CB  1 
ATOM 3503 C CG  . ARG D 3 106 ? 135.987 116.057 87.935  1.00 38.55  ? 105 ARG C CG  1 
ATOM 3504 C CD  . ARG D 3 106 ? 135.773 114.687 87.330  1.00 38.55  ? 105 ARG C CD  1 
ATOM 3505 N NE  . ARG D 3 106 ? 136.166 113.618 88.237  1.00 38.55  ? 105 ARG C NE  1 
ATOM 3506 C CZ  . ARG D 3 106 ? 137.204 112.817 88.041  1.00 38.55  ? 105 ARG C CZ  1 
ATOM 3507 N NH1 . ARG D 3 106 ? 137.973 112.935 86.973  1.00 38.55  ? 105 ARG C NH1 1 
ATOM 3508 N NH2 . ARG D 3 106 ? 137.472 111.871 88.935  1.00 38.55  ? 105 ARG C NH2 1 
ATOM 3509 N N   . ALA D 3 107 ? 134.640 117.712 91.862  1.00 36.90  ? 106 ALA C N   1 
ATOM 3510 C CA  . ALA D 3 107 ? 133.899 117.995 93.086  1.00 36.90  ? 106 ALA C CA  1 
ATOM 3511 C C   . ALA D 3 107 ? 133.706 119.493 93.267  1.00 36.90  ? 106 ALA C C   1 
ATOM 3512 O O   . ALA D 3 107 ? 132.632 119.947 93.685  1.00 36.90  ? 106 ALA C O   1 
ATOM 3513 C CB  . ALA D 3 107 ? 134.624 117.397 94.290  1.00 36.90  ? 106 ALA C CB  1 
ATOM 3514 N N   . PHE D 3 108 ? 134.736 120.274 92.942  1.00 35.64  ? 107 PHE C N   1 
ATOM 3515 C CA  . PHE D 3 108 ? 134.642 121.724 93.039  1.00 35.64  ? 107 PHE C CA  1 
ATOM 3516 C C   . PHE D 3 108 ? 133.528 122.259 92.154  1.00 35.64  ? 107 PHE C C   1 
ATOM 3517 O O   . PHE D 3 108 ? 132.700 123.059 92.597  1.00 35.64  ? 107 PHE C O   1 
ATOM 3518 C CB  . PHE D 3 108 ? 135.972 122.356 92.644  1.00 35.64  ? 107 PHE C CB  1 
ATOM 3519 C CG  . PHE D 3 108 ? 136.069 123.807 92.974  1.00 35.64  ? 107 PHE C CG  1 
ATOM 3520 C CD1 . PHE D 3 108 ? 136.424 124.214 94.241  1.00 35.64  ? 107 PHE C CD1 1 
ATOM 3521 C CD2 . PHE D 3 108 ? 135.783 124.765 92.025  1.00 35.64  ? 107 PHE C CD2 1 
ATOM 3522 C CE1 . PHE D 3 108 ? 136.516 125.543 94.548  1.00 35.64  ? 107 PHE C CE1 1 
ATOM 3523 C CE2 . PHE D 3 108 ? 135.863 126.099 92.333  1.00 35.64  ? 107 PHE C CE2 1 
ATOM 3524 C CZ  . PHE D 3 108 ? 136.230 126.488 93.597  1.00 35.64  ? 107 PHE C CZ  1 
ATOM 3525 N N   . VAL D 3 109 ? 133.495 121.825 90.893  1.00 34.87  ? 108 VAL C N   1 
ATOM 3526 C CA  . VAL D 3 109 ? 132.485 122.324 89.962  1.00 34.87  ? 108 VAL C CA  1 
ATOM 3527 C C   . VAL D 3 109 ? 131.089 121.945 90.436  1.00 34.87  ? 108 VAL C C   1 
ATOM 3528 O O   . VAL D 3 109 ? 130.166 122.771 90.432  1.00 34.87  ? 108 VAL C O   1 
ATOM 3529 C CB  . VAL D 3 109 ? 132.757 121.801 88.542  1.00 34.87  ? 108 VAL C CB  1 
ATOM 3530 C CG1 . VAL D 3 109 ? 131.630 122.201 87.615  1.00 34.87  ? 108 VAL C CG1 1 
ATOM 3531 C CG2 . VAL D 3 109 ? 134.073 122.338 88.028  1.00 34.87  ? 108 VAL C CG2 1 
ATOM 3532 N N   . ARG D 3 110 ? 130.911 120.690 90.855  1.00 33.22  ? 109 ARG C N   1 
ATOM 3533 C CA  . ARG D 3 110 ? 129.585 120.234 91.264  1.00 33.22  ? 109 ARG C CA  1 
ATOM 3534 C C   . ARG D 3 110 ? 129.083 121.007 92.480  1.00 33.22  ? 109 ARG C C   1 
ATOM 3535 O O   . ARG D 3 110 ? 127.936 121.481 92.507  1.00 33.22  ? 109 ARG C O   1 
ATOM 3536 C CB  . ARG D 3 110 ? 129.622 118.734 91.546  1.00 33.22  ? 109 ARG C CB  1 
ATOM 3537 C CG  . ARG D 3 110 ? 128.568 118.251 92.512  1.00 33.22  ? 109 ARG C CG  1 
ATOM 3538 C CD  . ARG D 3 110 ? 128.854 116.832 92.948  1.00 33.22  ? 109 ARG C CD  1 
ATOM 3539 N NE  . ARG D 3 110 ? 129.674 116.795 94.151  1.00 33.22  ? 109 ARG C NE  1 
ATOM 3540 C CZ  . ARG D 3 110 ? 129.200 116.927 95.382  1.00 33.22  ? 109 ARG C CZ  1 
ATOM 3541 N NH1 . ARG D 3 110 ? 127.909 117.091 95.611  1.00 33.22  ? 109 ARG C NH1 1 
ATOM 3542 N NH2 . ARG D 3 110 ? 130.043 116.891 96.409  1.00 33.22  ? 109 ARG C NH2 1 
ATOM 3543 N N   . THR D 3 111 ? 129.935 121.168 93.495  1.00 33.86  ? 110 THR C N   1 
ATOM 3544 C CA  . THR D 3 111 ? 129.487 121.870 94.691  1.00 33.86  ? 110 THR C CA  1 
ATOM 3545 C C   . THR D 3 111 ? 129.313 123.362 94.435  1.00 33.86  ? 110 THR C C   1 
ATOM 3546 O O   . THR D 3 111 ? 128.430 123.991 95.029  1.00 33.86  ? 110 THR C O   1 
ATOM 3547 C CB  . THR D 3 111 ? 130.461 121.643 95.836  1.00 33.86  ? 110 THR C CB  1 
ATOM 3548 O OG1 . THR D 3 111 ? 130.560 120.240 96.100  1.00 33.86  ? 110 THR C OG1 1 
ATOM 3549 C CG2 . THR D 3 111 ? 129.940 122.321 97.082  1.00 33.86  ? 110 THR C CG2 1 
ATOM 3550 N N   . GLU D 3 112 ? 130.134 123.946 93.560  1.00 34.19  ? 111 GLU C N   1 
ATOM 3551 C CA  . GLU D 3 112 ? 129.932 125.337 93.181  1.00 34.19  ? 111 GLU C CA  1 
ATOM 3552 C C   . GLU D 3 112 ? 128.577 125.527 92.519  1.00 34.19  ? 111 GLU C C   1 
ATOM 3553 O O   . GLU D 3 112 ? 127.866 126.494 92.813  1.00 34.19  ? 111 GLU C O   1 
ATOM 3554 C CB  . GLU D 3 112 ? 131.053 125.791 92.249  1.00 34.19  ? 111 GLU C CB  1 
ATOM 3555 C CG  . GLU D 3 112 ? 130.874 127.186 91.687  1.00 34.19  ? 111 GLU C CG  1 
ATOM 3556 C CD  . GLU D 3 112 ? 132.051 127.626 90.838  1.00 34.19  ? 111 GLU C CD  1 
ATOM 3557 O OE1 . GLU D 3 112 ? 133.108 126.966 90.900  1.00 34.19  ? 111 GLU C OE1 1 
ATOM 3558 O OE2 . GLU D 3 112 ? 131.920 128.630 90.108  1.00 34.19  ? 111 GLU C OE2 1 
ATOM 3559 N N   . LEU D 3 113 ? 128.194 124.606 91.631  1.00 31.31  ? 112 LEU C N   1 
ATOM 3560 C CA  . LEU D 3 113 ? 126.879 124.699 91.006  1.00 31.31  ? 112 LEU C CA  1 
ATOM 3561 C C   . LEU D 3 113 ? 125.764 124.581 92.036  1.00 31.31  ? 112 LEU C C   1 
ATOM 3562 O O   . LEU D 3 113 ? 124.771 125.313 91.969  1.00 31.31  ? 112 LEU C O   1 
ATOM 3563 C CB  . LEU D 3 113 ? 126.722 123.630 89.929  1.00 31.31  ? 112 LEU C CB  1 
ATOM 3564 C CG  . LEU D 3 113 ? 125.414 123.714 89.144  1.00 31.31  ? 112 LEU C CG  1 
ATOM 3565 C CD1 . LEU D 3 113 ? 125.353 124.990 88.328  1.00 31.31  ? 112 LEU C CD1 1 
ATOM 3566 C CD2 . LEU D 3 113 ? 125.248 122.502 88.251  1.00 31.31  ? 112 LEU C CD2 1 
ATOM 3567 N N   . ALA D 3 114 ? 125.902 123.664 92.997  1.00 30.33  ? 113 ALA C N   1 
ATOM 3568 C CA  . ALA D 3 114 ? 124.864 123.528 94.021  1.00 30.33  ? 113 ALA C CA  1 
ATOM 3569 C C   . ALA D 3 114 ? 124.736 124.800 94.858  1.00 30.33  ? 113 ALA C C   1 
ATOM 3570 O O   . ALA D 3 114 ? 123.629 125.319 95.071  1.00 30.33  ? 113 ALA C O   1 
ATOM 3571 C CB  . ALA D 3 114 ? 125.160 122.324 94.913  1.00 30.33  ? 113 ALA C CB  1 
ATOM 3572 N N   . ALA D 3 115 ? 125.868 125.325 95.335  1.00 31.27  ? 114 ALA C N   1 
ATOM 3573 C CA  . ALA D 3 115 ? 125.839 126.535 96.148  1.00 31.27  ? 114 ALA C CA  1 
ATOM 3574 C C   . ALA D 3 115 ? 125.306 127.723 95.364  1.00 31.27  ? 114 ALA C C   1 
ATOM 3575 O O   . ALA D 3 115 ? 124.649 128.599 95.935  1.00 31.27  ? 114 ALA C O   1 
ATOM 3576 C CB  . ALA D 3 115 ? 127.234 126.840 96.687  1.00 31.27  ? 114 ALA C CB  1 
ATOM 3577 N N   . LEU D 3 116 ? 125.581 127.778 94.062  1.00 31.28  ? 115 LEU C N   1 
ATOM 3578 C CA  . LEU D 3 116 ? 125.007 128.816 93.220  1.00 31.28  ? 115 LEU C CA  1 
ATOM 3579 C C   . LEU D 3 116 ? 123.504 128.646 93.064  1.00 31.28  ? 115 LEU C C   1 
ATOM 3580 O O   . LEU D 3 116 ? 122.775 129.640 93.001  1.00 31.28  ? 115 LEU C O   1 
ATOM 3581 C CB  . LEU D 3 116 ? 125.685 128.802 91.854  1.00 31.28  ? 115 LEU C CB  1 
ATOM 3582 C CG  . LEU D 3 116 ? 125.879 130.144 91.165  1.00 31.28  ? 115 LEU C CG  1 
ATOM 3583 C CD1 . LEU D 3 116 ? 126.530 131.125 92.112  1.00 31.28  ? 115 LEU C CD1 1 
ATOM 3584 C CD2 . LEU D 3 116 ? 126.734 129.940 89.942  1.00 31.28  ? 115 LEU C CD2 1 
ATOM 3585 N N   . LEU D 3 117 ? 123.028 127.402 92.986  1.00 31.23  ? 116 LEU C N   1 
ATOM 3586 C CA  . LEU D 3 117 ? 121.590 127.165 92.954  1.00 31.23  ? 116 LEU C CA  1 
ATOM 3587 C C   . LEU D 3 117 ? 120.921 127.639 94.234  1.00 31.23  ? 116 LEU C C   1 
ATOM 3588 O O   . LEU D 3 117 ? 119.761 128.063 94.203  1.00 31.23  ? 116 LEU C O   1 
ATOM 3589 C CB  . LEU D 3 117 ? 121.296 125.683 92.731  1.00 31.23  ? 116 LEU C CB  1 
ATOM 3590 C CG  . LEU D 3 117 ? 121.479 125.125 91.323  1.00 31.23  ? 116 LEU C CG  1 
ATOM 3591 C CD1 . LEU D 3 117 ? 121.040 123.681 91.285  1.00 31.23  ? 116 LEU C CD1 1 
ATOM 3592 C CD2 . LEU D 3 117 ? 120.698 125.940 90.320  1.00 31.23  ? 116 LEU C CD2 1 
ATOM 3593 N N   . ALA D 3 118 ? 121.619 127.567 95.362  1.00 32.49  ? 117 ALA C N   1 
ATOM 3594 C CA  . ALA D 3 118 ? 121.067 128.082 96.611  1.00 32.49  ? 117 ALA C CA  1 
ATOM 3595 C C   . ALA D 3 118 ? 121.389 129.555 96.852  1.00 32.49  ? 117 ALA C C   1 
ATOM 3596 O O   . ALA D 3 118 ? 121.013 130.091 97.899  1.00 32.49  ? 117 ALA C O   1 
ATOM 3597 C CB  . ALA D 3 118 ? 121.564 127.249 97.795  1.00 32.49  ? 117 ALA C CB  1 
ATOM 3598 N N   . SER D 3 119 ? 122.071 130.216 95.920  1.00 36.05  ? 118 SER C N   1 
ATOM 3599 C CA  . SER D 3 119 ? 122.509 131.591 96.118  1.00 36.05  ? 118 SER C CA  1 
ATOM 3600 C C   . SER D 3 119 ? 121.325 132.558 96.078  1.00 36.05  ? 118 SER C C   1 
ATOM 3601 O O   . SER D 3 119 ? 120.353 132.330 95.357  1.00 36.05  ? 118 SER C O   1 
ATOM 3602 C CB  . SER D 3 119 ? 123.524 131.972 95.044  1.00 36.05  ? 118 SER C CB  1 
ATOM 3603 O OG  . SER D 3 119 ? 123.883 133.338 95.121  1.00 36.05  ? 118 SER C OG  1 
ATOM 3604 N N   . PRO D 3 120 ? 121.393 133.663 96.831  1.00 39.17  ? 119 PRO C N   1 
ATOM 3605 C CA  . PRO D 3 120 ? 120.278 134.627 96.836  1.00 39.17  ? 119 PRO C CA  1 
ATOM 3606 C C   . PRO D 3 120 ? 120.031 135.309 95.500  1.00 39.17  ? 119 PRO C C   1 
ATOM 3607 O O   . PRO D 3 120 ? 118.958 135.896 95.319  1.00 39.17  ? 119 PRO C O   1 
ATOM 3608 C CB  . PRO D 3 120 ? 120.689 135.650 97.904  1.00 39.17  ? 119 PRO C CB  1 
ATOM 3609 C CG  . PRO D 3 120 ? 122.135 135.455 98.124  1.00 39.17  ? 119 PRO C CG  1 
ATOM 3610 C CD  . PRO D 3 120 ? 122.478 134.052 97.748  1.00 39.17  ? 119 PRO C CD  1 
ATOM 3611 N N   . LEU D 3 121 ? 120.983 135.267 94.570  1.00 39.79  ? 120 LEU C N   1 
ATOM 3612 C CA  . LEU D 3 121 ? 120.763 135.837 93.245  1.00 39.79  ? 120 LEU C CA  1 
ATOM 3613 C C   . LEU D 3 121 ? 119.962 134.886 92.366  1.00 39.79  ? 120 LEU C C   1 
ATOM 3614 O O   . LEU D 3 121 ? 118.930 135.261 91.794  1.00 39.79  ? 120 LEU C O   1 
ATOM 3615 C CB  . LEU D 3 121 ? 122.112 136.162 92.599  1.00 39.79  ? 120 LEU C CB  1 
ATOM 3616 C CG  . LEU D 3 121 ? 122.193 136.927 91.276  1.00 39.79  ? 120 LEU C CG  1 
ATOM 3617 C CD1 . LEU D 3 121 ? 123.515 137.667 91.197  1.00 39.79  ? 120 LEU C CD1 1 
ATOM 3618 C CD2 . LEU D 3 121 ? 122.058 135.997 90.085  1.00 39.79  ? 120 LEU C CD2 1 
ATOM 3619 N N   . LEU D 3 122 ? 120.425 133.644 92.249  1.00 38.88  ? 121 LEU C N   1 
ATOM 3620 C CA  . LEU D 3 122 ? 119.814 132.729 91.299  1.00 38.88  ? 121 LEU C CA  1 
ATOM 3621 C C   . LEU D 3 122 ? 118.449 132.250 91.778  1.00 38.88  ? 121 LEU C C   1 
ATOM 3622 O O   . LEU D 3 122 ? 117.590 131.920 90.952  1.00 38.88  ? 121 LEU C O   1 
ATOM 3623 C CB  . LEU D 3 122 ? 120.759 131.559 91.039  1.00 38.88  ? 121 LEU C CB  1 
ATOM 3624 C CG  . LEU D 3 122 ? 120.312 130.560 89.983  1.00 38.88  ? 121 LEU C CG  1 
ATOM 3625 C CD1 . LEU D 3 122 ? 120.191 131.261 88.652  1.00 38.88  ? 121 LEU C CD1 1 
ATOM 3626 C CD2 . LEU D 3 122 ? 121.318 129.441 89.889  1.00 38.88  ? 121 LEU C CD2 1 
ATOM 3627 N N   . ILE D 3 123 ? 118.209 132.244 93.092  1.00 39.36  ? 122 ILE C N   1 
ATOM 3628 C CA  . ILE D 3 123 ? 116.888 131.857 93.580  1.00 39.36  ? 122 ILE C CA  1 
ATOM 3629 C C   . ILE D 3 123 ? 115.829 132.814 93.054  1.00 39.36  ? 122 ILE C C   1 
ATOM 3630 O O   . ILE D 3 123 ? 114.768 132.384 92.593  1.00 39.36  ? 122 ILE C O   1 
ATOM 3631 C CB  . ILE D 3 123 ? 116.855 131.763 95.118  1.00 39.36  ? 122 ILE C CB  1 
ATOM 3632 C CG1 . ILE D 3 123 ? 117.220 133.088 95.778  1.00 39.36  ? 122 ILE C CG1 1 
ATOM 3633 C CG2 . ILE D 3 123 ? 117.754 130.649 95.613  1.00 39.36  ? 122 ILE C CG2 1 
ATOM 3634 C CD1 . ILE D 3 123 ? 116.940 133.107 97.258  1.00 39.36  ? 122 ILE C CD1 1 
ATOM 3635 N N   . ASP D 3 124 ? 116.099 134.120 93.089  1.00 43.46  ? 123 ASP C N   1 
ATOM 3636 C CA  . ASP D 3 124 ? 115.119 135.054 92.553  1.00 43.46  ? 123 ASP C CA  1 
ATOM 3637 C C   . ASP D 3 124 ? 115.129 135.062 91.031  1.00 43.46  ? 123 ASP C C   1 
ATOM 3638 O O   . ASP D 3 124 ? 114.068 135.209 90.414  1.00 43.46  ? 123 ASP C O   1 
ATOM 3639 C CB  . ASP D 3 124 ? 115.328 136.457 93.151  1.00 43.46  ? 123 ASP C CB  1 
ATOM 3640 C CG  . ASP D 3 124 ? 116.490 137.238 92.532  1.00 43.46  ? 123 ASP C CG  1 
ATOM 3641 O OD1 . ASP D 3 124 ? 116.952 136.950 91.412  1.00 43.46  ? 123 ASP C OD1 1 
ATOM 3642 O OD2 . ASP D 3 124 ? 116.955 138.182 93.203  1.00 43.46  ? 123 ASP C OD2 1 
ATOM 3643 N N   . ALA D 3 125 ? 116.301 134.873 90.414  1.00 40.09  ? 124 ALA C N   1 
ATOM 3644 C CA  . ALA D 3 125 ? 116.358 134.810 88.956  1.00 40.09  ? 124 ALA C CA  1 
ATOM 3645 C C   . ALA D 3 125 ? 115.549 133.643 88.404  1.00 40.09  ? 124 ALA C C   1 
ATOM 3646 O O   . ALA D 3 125 ? 115.119 133.684 87.247  1.00 40.09  ? 124 ALA C O   1 
ATOM 3647 C CB  . ALA D 3 125 ? 117.808 134.711 88.488  1.00 40.09  ? 124 ALA C CB  1 
ATOM 3648 N N   . ILE D 3 126 ? 115.341 132.596 89.198  1.00 39.74  ? 125 ILE C N   1 
ATOM 3649 C CA  . ILE D 3 126 ? 114.521 131.469 88.757  1.00 39.74  ? 125 ILE C CA  1 
ATOM 3650 C C   . ILE D 3 126 ? 113.077 131.605 89.226  1.00 39.74  ? 125 ILE C C   1 
ATOM 3651 O O   . ILE D 3 126 ? 112.144 131.396 88.449  1.00 39.74  ? 125 ILE C O   1 
ATOM 3652 C CB  . ILE D 3 126 ? 115.138 130.138 89.231  1.00 39.74  ? 125 ILE C CB  1 
ATOM 3653 C CG1 . ILE D 3 126 ? 116.511 129.930 88.599  1.00 39.74  ? 125 ILE C CG1 1 
ATOM 3654 C CG2 . ILE D 3 126 ? 114.234 128.979 88.878  1.00 39.74  ? 125 ILE C CG2 1 
ATOM 3655 C CD1 . ILE D 3 126 ? 117.277 128.788 89.209  1.00 39.74  ? 125 ILE C CD1 1 
ATOM 3656 N N   . ASP D 3 127 ? 112.858 131.940 90.499  1.00 42.97  ? 126 ASP C N   1 
ATOM 3657 C CA  . ASP D 3 127 ? 111.499 132.014 91.026  1.00 42.97  ? 126 ASP C CA  1 
ATOM 3658 C C   . ASP D 3 127 ? 110.712 133.154 90.394  1.00 42.97  ? 126 ASP C C   1 
ATOM 3659 O O   . ASP D 3 127 ? 109.588 132.954 89.921  1.00 42.97  ? 126 ASP C O   1 
ATOM 3660 C CB  . ASP D 3 127 ? 111.538 132.175 92.544  1.00 42.97  ? 126 ASP C CB  1 
ATOM 3661 C CG  . ASP D 3 127 ? 112.079 130.951 93.245  1.00 42.97  ? 126 ASP C CG  1 
ATOM 3662 O OD1 . ASP D 3 127 ? 112.883 130.223 92.629  1.00 42.97  ? 126 ASP C OD1 1 
ATOM 3663 O OD2 . ASP D 3 127 ? 111.711 130.724 94.417  1.00 42.97  ? 126 ASP C OD2 1 
ATOM 3664 N N   . GLN D 3 128 ? 111.277 134.360 90.380  1.00 44.75  ? 127 GLN C N   1 
ATOM 3665 C CA  . GLN D 3 128 ? 110.561 135.534 89.901  1.00 44.75  ? 127 GLN C CA  1 
ATOM 3666 C C   . GLN D 3 128 ? 110.974 135.961 88.501  1.00 44.75  ? 127 GLN C C   1 
ATOM 3667 O O   . GLN D 3 128 ? 110.430 136.941 87.987  1.00 44.75  ? 127 GLN C O   1 
ATOM 3668 C CB  . GLN D 3 128 ? 110.750 136.701 90.871  1.00 44.75  ? 127 GLN C CB  1 
ATOM 3669 C CG  . GLN D 3 128 ? 109.871 136.616 92.102  1.00 44.75  ? 127 GLN C CG  1 
ATOM 3670 C CD  . GLN D 3 128 ? 110.524 135.849 93.229  1.00 44.75  ? 127 GLN C CD  1 
ATOM 3671 O OE1 . GLN D 3 128 ? 111.747 135.738 93.290  1.00 44.75  ? 127 GLN C OE1 1 
ATOM 3672 N NE2 . GLN D 3 128 ? 109.710 135.309 94.127  1.00 44.75  ? 127 GLN C NE2 1 
ATOM 3673 N N   . LEU D 3 129 ? 111.916 135.254 87.879  1.00 43.01  ? 128 LEU C N   1 
ATOM 3674 C CA  . LEU D 3 129 ? 112.346 135.534 86.509  1.00 43.01  ? 128 LEU C CA  1 
ATOM 3675 C C   . LEU D 3 129 ? 112.871 136.957 86.351  1.00 43.01  ? 128 LEU C C   1 
ATOM 3676 O O   . LEU D 3 129 ? 112.704 137.579 85.301  1.00 43.01  ? 128 LEU C O   1 
ATOM 3677 C CB  . LEU D 3 129 ? 111.217 135.269 85.511  1.00 43.01  ? 128 LEU C CB  1 
ATOM 3678 C CG  . LEU D 3 129 ? 111.084 133.844 84.976  1.00 43.01  ? 128 LEU C CG  1 
ATOM 3679 C CD1 . LEU D 3 129 ? 110.701 132.888 86.072  1.00 43.01  ? 128 LEU C CD1 1 
ATOM 3680 C CD2 . LEU D 3 129 ? 110.039 133.812 83.895  1.00 43.01  ? 128 LEU C CD2 1 
ATOM 3681 N N   . ASN D 3 130 ? 113.504 137.484 87.389  1.00 46.05  ? 129 ASN C N   1 
ATOM 3682 C CA  . ASN D 3 130 ? 114.101 138.808 87.313  1.00 46.05  ? 129 ASN C CA  1 
ATOM 3683 C C   . ASN D 3 130 ? 115.467 138.720 86.646  1.00 46.05  ? 129 ASN C C   1 
ATOM 3684 O O   . ASN D 3 130 ? 116.351 138.031 87.164  1.00 46.05  ? 129 ASN C O   1 
ATOM 3685 C CB  . ASN D 3 130 ? 114.244 139.410 88.703  1.00 46.05  ? 129 ASN C CB  1 
ATOM 3686 C CG  . ASN D 3 130 ? 112.922 139.842 89.291  1.00 46.05  ? 129 ASN C CG  1 
ATOM 3687 O OD1 . ASN D 3 130 ? 111.951 140.057 88.569  1.00 46.05  ? 129 ASN C OD1 1 
ATOM 3688 N ND2 . ASN D 3 130 ? 112.877 139.978 90.609  1.00 46.05  ? 129 ASN C ND2 1 
ATOM 3689 N N   . PRO D 3 131 ? 115.685 139.386 85.517  1.00 45.43  ? 130 PRO C N   1 
ATOM 3690 C CA  . PRO D 3 131 ? 117.025 139.416 84.926  1.00 45.43  ? 130 PRO C CA  1 
ATOM 3691 C C   . PRO D 3 131 ? 118.006 140.127 85.844  1.00 45.43  ? 130 PRO C C   1 
ATOM 3692 O O   . PRO D 3 131 ? 117.653 141.019 86.616  1.00 45.43  ? 130 PRO C O   1 
ATOM 3693 C CB  . PRO D 3 131 ? 116.827 140.184 83.617  1.00 45.43  ? 130 PRO C CB  1 
ATOM 3694 C CG  . PRO D 3 131 ? 115.368 140.079 83.331  1.00 45.43  ? 130 PRO C CG  1 
ATOM 3695 C CD  . PRO D 3 131 ? 114.696 140.065 84.666  1.00 45.43  ? 130 PRO C CD  1 
ATOM 3696 N N   . ALA D 3 132 ? 119.263 139.709 85.755  1.00 44.74  ? 131 ALA C N   1 
ATOM 3697 C CA  . ALA D 3 132 ? 120.312 140.279 86.593  1.00 44.74  ? 131 ALA C CA  1 
ATOM 3698 C C   . ALA D 3 132 ? 121.037 141.412 85.877  1.00 44.74  ? 131 ALA C C   1 
ATOM 3699 O O   . ALA D 3 132 ? 121.040 142.551 86.344  1.00 44.74  ? 131 ALA C O   1 
ATOM 3700 C CB  . ALA D 3 132 ? 121.295 139.203 87.011  1.00 44.74  ? 131 ALA C CB  1 
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