data_8W5E
# 
_entry.id   8W5E 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8W5E         pdb_00008w5e 10.2210/pdb8w5e/pdb 
WWPDB D_1300040590 ?            ?                   
EMDB  EMD-37287    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-02-26 ? 
2 'EM metadata'     1 0 2025-02-26 ? 
3 'Half map'        1 0 2025-02-26 1 
4 'Half map'        1 0 2025-02-26 2 
5 Image             1 0 2025-02-26 ? 
6 'Primary map'     1 0 2025-02-26 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Half map'        repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 Image             repository 'Initial release' ? ? 
6 6 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8W5E 
_pdbx_database_status.recvd_initial_deposition_date   2023-08-26 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure of Qb-Ab4' 
_pdbx_database_related.db_id          EMD-37287 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              zhup@ibp.ac.cn 
_pdbx_contact_author.name_first         Ping 
_pdbx_contact_author.name_last          Zhu 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-2648-3170 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Bao, K.Y.' 1 ? 
'Li, R.H.'  2 ? 
'Hua, Z.L.' 3 ? 
'Hou, B.D.' 4 ? 
'Zhu, P.'   5 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Cell Rep' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2211-1247 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            44 
_citation.language                  ? 
_citation.page_first                115334 
_citation.page_last                 115334 
_citation.title                     
'Competition propels, rather than limits, the success of low-affinity B cells in the germinal center response.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.celrep.2025.115334 
_citation.pdbx_database_id_PubMed   39955776 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Li, R.'  1 ? 
primary 'Bao, K.' 2 ? 
primary 'Liu, C.' 3 ? 
primary 'Ma, X.'  4 ? 
primary 'Hua, Z.' 5 ? 
primary 'Zhu, P.' 6 ? 
primary 'Hou, B.' 7 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man 'Heavy chain of Ab4'      13855.258 1 ? ? ? ? 
2 polymer man 'Minor capsid protein A1' 14268.071 2 ? ? ? ? 
3 polymer man 'Light chain of Ab4'      12101.261 1 ? ? ? ? 
# 
_entity_name_com.entity_id   2 
_entity_name_com.name        'Qb coat protein' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no yes 
;VHSEVQLVESGGGLVQPGGSLKLSCAASGFTFSDYGMAWVRQAPRKGPEWVAFISNLAYSIYYADTVTGRFTI(SEP)RE
NAKNTLYLEMSSLRSEDTAMYYCARQNFDSSFYFDYWGRGTTLTVSSA
;
;VHSEVQLVESGGGLVQPGGSLKLSCAASGFTFSDYGMAWVRQAPRKGPEWVAFISNLAYSIYYADTVTGRFTISRENAKN
TLYLEMSSLRSEDTAMYYCARQNFDSSFYFDYWGRGTTLTVSSA
;
H   ? 
2 'polypeptide(L)' no no  
;MAKLETVTLGNIGKDGKQTLVLNPRGVNPTNGVASLSQAGAVPALEKRVTVSVSQPSRNRKNYKVQVKIQNPTACTANGS
CDPSVTRQAYADVTFSFTQYSTDEERAFVRTELAALLASPLLIDAIDQLNPAY
;
;MAKLETVTLGNIGKDGKQTLVLNPRGVNPTNGVASLSQAGAVPALEKRVTVSVSQPSRNRKNYKVQVKIQNPTACTANGS
CDPSVTRQAYADVTFSFTQYSTDEERAFVRTELAALLASPLLIDAIDQLNPAY
;
c,C ? 
3 'polypeptide(L)' no yes 
;VHSETTVTQSPASL(SEP)VATGEKVTIRCITSTDIDDDMNWYQQKPGEPPKLLISEGNTLRPGVPSRFSSSGYGTDFVF
TIENTLSEDVADYYCLQSDNMPLTFGAGTKLEIK
;
;VHSETTVTQSPASLSVATGEKVTIRCITSTDIDDDMNWYQQKPGEPPKLLISEGNTLRPGVPSRFSSSGYGTDFVFTIEN
TLSEDVADYYCLQSDNMPLTFGAGTKLEIK
;
L   ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   VAL n 
1 2   HIS n 
1 3   SER n 
1 4   GLU n 
1 5   VAL n 
1 6   GLN n 
1 7   LEU n 
1 8   VAL n 
1 9   GLU n 
1 10  SER n 
1 11  GLY n 
1 12  GLY n 
1 13  GLY n 
1 14  LEU n 
1 15  VAL n 
1 16  GLN n 
1 17  PRO n 
1 18  GLY n 
1 19  GLY n 
1 20  SER n 
1 21  LEU n 
1 22  LYS n 
1 23  LEU n 
1 24  SER n 
1 25  CYS n 
1 26  ALA n 
1 27  ALA n 
1 28  SER n 
1 29  GLY n 
1 30  PHE n 
1 31  THR n 
1 32  PHE n 
1 33  SER n 
1 34  ASP n 
1 35  TYR n 
1 36  GLY n 
1 37  MET n 
1 38  ALA n 
1 39  TRP n 
1 40  VAL n 
1 41  ARG n 
1 42  GLN n 
1 43  ALA n 
1 44  PRO n 
1 45  ARG n 
1 46  LYS n 
1 47  GLY n 
1 48  PRO n 
1 49  GLU n 
1 50  TRP n 
1 51  VAL n 
1 52  ALA n 
1 53  PHE n 
1 54  ILE n 
1 55  SER n 
1 56  ASN n 
1 57  LEU n 
1 58  ALA n 
1 59  TYR n 
1 60  SER n 
1 61  ILE n 
1 62  TYR n 
1 63  TYR n 
1 64  ALA n 
1 65  ASP n 
1 66  THR n 
1 67  VAL n 
1 68  THR n 
1 69  GLY n 
1 70  ARG n 
1 71  PHE n 
1 72  THR n 
1 73  ILE n 
1 74  SEP n 
1 75  ARG n 
1 76  GLU n 
1 77  ASN n 
1 78  ALA n 
1 79  LYS n 
1 80  ASN n 
1 81  THR n 
1 82  LEU n 
1 83  TYR n 
1 84  LEU n 
1 85  GLU n 
1 86  MET n 
1 87  SER n 
1 88  SER n 
1 89  LEU n 
1 90  ARG n 
1 91  SER n 
1 92  GLU n 
1 93  ASP n 
1 94  THR n 
1 95  ALA n 
1 96  MET n 
1 97  TYR n 
1 98  TYR n 
1 99  CYS n 
1 100 ALA n 
1 101 ARG n 
1 102 GLN n 
1 103 ASN n 
1 104 PHE n 
1 105 ASP n 
1 106 SER n 
1 107 SER n 
1 108 PHE n 
1 109 TYR n 
1 110 PHE n 
1 111 ASP n 
1 112 TYR n 
1 113 TRP n 
1 114 GLY n 
1 115 ARG n 
1 116 GLY n 
1 117 THR n 
1 118 THR n 
1 119 LEU n 
1 120 THR n 
1 121 VAL n 
1 122 SER n 
1 123 SER n 
1 124 ALA n 
2 1   MET n 
2 2   ALA n 
2 3   LYS n 
2 4   LEU n 
2 5   GLU n 
2 6   THR n 
2 7   VAL n 
2 8   THR n 
2 9   LEU n 
2 10  GLY n 
2 11  ASN n 
2 12  ILE n 
2 13  GLY n 
2 14  LYS n 
2 15  ASP n 
2 16  GLY n 
2 17  LYS n 
2 18  GLN n 
2 19  THR n 
2 20  LEU n 
2 21  VAL n 
2 22  LEU n 
2 23  ASN n 
2 24  PRO n 
2 25  ARG n 
2 26  GLY n 
2 27  VAL n 
2 28  ASN n 
2 29  PRO n 
2 30  THR n 
2 31  ASN n 
2 32  GLY n 
2 33  VAL n 
2 34  ALA n 
2 35  SER n 
2 36  LEU n 
2 37  SER n 
2 38  GLN n 
2 39  ALA n 
2 40  GLY n 
2 41  ALA n 
2 42  VAL n 
2 43  PRO n 
2 44  ALA n 
2 45  LEU n 
2 46  GLU n 
2 47  LYS n 
2 48  ARG n 
2 49  VAL n 
2 50  THR n 
2 51  VAL n 
2 52  SER n 
2 53  VAL n 
2 54  SER n 
2 55  GLN n 
2 56  PRO n 
2 57  SER n 
2 58  ARG n 
2 59  ASN n 
2 60  ARG n 
2 61  LYS n 
2 62  ASN n 
2 63  TYR n 
2 64  LYS n 
2 65  VAL n 
2 66  GLN n 
2 67  VAL n 
2 68  LYS n 
2 69  ILE n 
2 70  GLN n 
2 71  ASN n 
2 72  PRO n 
2 73  THR n 
2 74  ALA n 
2 75  CYS n 
2 76  THR n 
2 77  ALA n 
2 78  ASN n 
2 79  GLY n 
2 80  SER n 
2 81  CYS n 
2 82  ASP n 
2 83  PRO n 
2 84  SER n 
2 85  VAL n 
2 86  THR n 
2 87  ARG n 
2 88  GLN n 
2 89  ALA n 
2 90  TYR n 
2 91  ALA n 
2 92  ASP n 
2 93  VAL n 
2 94  THR n 
2 95  PHE n 
2 96  SER n 
2 97  PHE n 
2 98  THR n 
2 99  GLN n 
2 100 TYR n 
2 101 SER n 
2 102 THR n 
2 103 ASP n 
2 104 GLU n 
2 105 GLU n 
2 106 ARG n 
2 107 ALA n 
2 108 PHE n 
2 109 VAL n 
2 110 ARG n 
2 111 THR n 
2 112 GLU n 
2 113 LEU n 
2 114 ALA n 
2 115 ALA n 
2 116 LEU n 
2 117 LEU n 
2 118 ALA n 
2 119 SER n 
2 120 PRO n 
2 121 LEU n 
2 122 LEU n 
2 123 ILE n 
2 124 ASP n 
2 125 ALA n 
2 126 ILE n 
2 127 ASP n 
2 128 GLN n 
2 129 LEU n 
2 130 ASN n 
2 131 PRO n 
2 132 ALA n 
2 133 TYR n 
3 1   VAL n 
3 2   HIS n 
3 3   SER n 
3 4   GLU n 
3 5   THR n 
3 6   THR n 
3 7   VAL n 
3 8   THR n 
3 9   GLN n 
3 10  SER n 
3 11  PRO n 
3 12  ALA n 
3 13  SER n 
3 14  LEU n 
3 15  SEP n 
3 16  VAL n 
3 17  ALA n 
3 18  THR n 
3 19  GLY n 
3 20  GLU n 
3 21  LYS n 
3 22  VAL n 
3 23  THR n 
3 24  ILE n 
3 25  ARG n 
3 26  CYS n 
3 27  ILE n 
3 28  THR n 
3 29  SER n 
3 30  THR n 
3 31  ASP n 
3 32  ILE n 
3 33  ASP n 
3 34  ASP n 
3 35  ASP n 
3 36  MET n 
3 37  ASN n 
3 38  TRP n 
3 39  TYR n 
3 40  GLN n 
3 41  GLN n 
3 42  LYS n 
3 43  PRO n 
3 44  GLY n 
3 45  GLU n 
3 46  PRO n 
3 47  PRO n 
3 48  LYS n 
3 49  LEU n 
3 50  LEU n 
3 51  ILE n 
3 52  SER n 
3 53  GLU n 
3 54  GLY n 
3 55  ASN n 
3 56  THR n 
3 57  LEU n 
3 58  ARG n 
3 59  PRO n 
3 60  GLY n 
3 61  VAL n 
3 62  PRO n 
3 63  SER n 
3 64  ARG n 
3 65  PHE n 
3 66  SER n 
3 67  SER n 
3 68  SER n 
3 69  GLY n 
3 70  TYR n 
3 71  GLY n 
3 72  THR n 
3 73  ASP n 
3 74  PHE n 
3 75  VAL n 
3 76  PHE n 
3 77  THR n 
3 78  ILE n 
3 79  GLU n 
3 80  ASN n 
3 81  THR n 
3 82  LEU n 
3 83  SER n 
3 84  GLU n 
3 85  ASP n 
3 86  VAL n 
3 87  ALA n 
3 88  ASP n 
3 89  TYR n 
3 90  TYR n 
3 91  CYS n 
3 92  LEU n 
3 93  GLN n 
3 94  SER n 
3 95  ASP n 
3 96  ASN n 
3 97  MET n 
3 98  PRO n 
3 99  LEU n 
3 100 THR n 
3 101 PHE n 
3 102 GLY n 
3 103 ALA n 
3 104 GLY n 
3 105 THR n 
3 106 LYS n 
3 107 LEU n 
3 108 GLU n 
3 109 ILE n 
3 110 LYS n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 124 ? ? ? ? ? ? ? ? ? 'Mus musculus'            10090   ? ? ? ? ? ? ? ? 'Homo sapiens'     9606 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 133 ? ? ? ? ? ? ? ? ? 'Escherichia phage Qbeta' 2789016 ? ? ? ? ? ? ? ? 'Escherichia coli' 562  
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
3 1 sample 'Biological sequence' 1 110 ? ? ? ? ? ? ? ? ? 'Mus musculus'            10090   ? ? ? ? ? ? ? ? 'Homo sapiens'     9606 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ?               'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ?               'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ?               'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ?               'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ?               'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ?               'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ?               'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ?               'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ?               'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ?               'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ?               'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ?               'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ?               'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ?               'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ?               'C5 H9 N O2'     115.130 
SEP 'L-peptide linking' n PHOSPHOSERINE   PHOSPHONOSERINE 'C3 H8 N O6 P'   185.072 
SER 'L-peptide linking' y SERINE          ?               'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ?               'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ?               'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ?               'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ?               'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   VAL 1   1   ?   ?   ?   H . n 
A 1 2   HIS 2   2   ?   ?   ?   H . n 
A 1 3   SER 3   3   ?   ?   ?   H . n 
A 1 4   GLU 4   4   ?   ?   ?   H . n 
A 1 5   VAL 5   5   5   VAL VAL H . n 
A 1 6   GLN 6   6   6   GLN GLN H . n 
A 1 7   LEU 7   7   7   LEU LEU H . n 
A 1 8   VAL 8   8   8   VAL VAL H . n 
A 1 9   GLU 9   9   9   GLU GLU H . n 
A 1 10  SER 10  10  10  SER SER H . n 
A 1 11  GLY 11  11  11  GLY GLY H . n 
A 1 12  GLY 12  12  12  GLY GLY H . n 
A 1 13  GLY 13  13  13  GLY GLY H . n 
A 1 14  LEU 14  14  14  LEU LEU H . n 
A 1 15  VAL 15  15  15  VAL VAL H . n 
A 1 16  GLN 16  16  16  GLN GLN H . n 
A 1 17  PRO 17  17  17  PRO PRO H . n 
A 1 18  GLY 18  18  18  GLY GLY H . n 
A 1 19  GLY 19  19  19  GLY GLY H . n 
A 1 20  SER 20  20  20  SER SER H . n 
A 1 21  LEU 21  21  21  LEU LEU H . n 
A 1 22  LYS 22  22  22  LYS LYS H . n 
A 1 23  LEU 23  23  23  LEU LEU H . n 
A 1 24  SER 24  24  24  SER SER H . n 
A 1 25  CYS 25  25  25  CYS CYS H . n 
A 1 26  ALA 26  26  26  ALA ALA H . n 
A 1 27  ALA 27  27  27  ALA ALA H . n 
A 1 28  SER 28  28  28  SER SER H . n 
A 1 29  GLY 29  29  29  GLY GLY H . n 
A 1 30  PHE 30  30  30  PHE PHE H . n 
A 1 31  THR 31  31  31  THR THR H . n 
A 1 32  PHE 32  32  32  PHE PHE H . n 
A 1 33  SER 33  33  33  SER SER H . n 
A 1 34  ASP 34  34  34  ASP ASP H . n 
A 1 35  TYR 35  35  35  TYR TYR H . n 
A 1 36  GLY 36  36  36  GLY GLY H . n 
A 1 37  MET 37  37  37  MET MET H . n 
A 1 38  ALA 38  38  38  ALA ALA H . n 
A 1 39  TRP 39  39  39  TRP TRP H . n 
A 1 40  VAL 40  40  40  VAL VAL H . n 
A 1 41  ARG 41  41  41  ARG ARG H . n 
A 1 42  GLN 42  42  42  GLN GLN H . n 
A 1 43  ALA 43  43  43  ALA ALA H . n 
A 1 44  PRO 44  44  44  PRO PRO H . n 
A 1 45  ARG 45  45  45  ARG ARG H . n 
A 1 46  LYS 46  46  46  LYS LYS H . n 
A 1 47  GLY 47  47  47  GLY GLY H . n 
A 1 48  PRO 48  48  48  PRO PRO H . n 
A 1 49  GLU 49  49  49  GLU GLU H . n 
A 1 50  TRP 50  50  50  TRP TRP H . n 
A 1 51  VAL 51  51  51  VAL VAL H . n 
A 1 52  ALA 52  52  52  ALA ALA H . n 
A 1 53  PHE 53  53  53  PHE PHE H . n 
A 1 54  ILE 54  54  54  ILE ILE H . n 
A 1 55  SER 55  55  55  SER SER H . n 
A 1 56  ASN 56  56  56  ASN ASN H . n 
A 1 57  LEU 57  57  57  LEU LEU H . n 
A 1 58  ALA 58  58  58  ALA ALA H . n 
A 1 59  TYR 59  59  59  TYR TYR H . n 
A 1 60  SER 60  60  60  SER SER H . n 
A 1 61  ILE 61  61  61  ILE ILE H . n 
A 1 62  TYR 62  62  62  TYR TYR H . n 
A 1 63  TYR 63  63  63  TYR TYR H . n 
A 1 64  ALA 64  64  64  ALA ALA H . n 
A 1 65  ASP 65  65  65  ASP ASP H . n 
A 1 66  THR 66  66  66  THR THR H . n 
A 1 67  VAL 67  67  67  VAL VAL H . n 
A 1 68  THR 68  68  68  THR THR H . n 
A 1 69  GLY 69  69  69  GLY GLY H . n 
A 1 70  ARG 70  70  70  ARG ARG H . n 
A 1 71  PHE 71  71  71  PHE PHE H . n 
A 1 72  THR 72  72  72  THR THR H . n 
A 1 73  ILE 73  73  73  ILE ILE H . n 
A 1 74  SEP 74  74  74  SEP SEP H . n 
A 1 75  ARG 75  75  75  ARG ARG H . n 
A 1 76  GLU 76  76  76  GLU GLU H . n 
A 1 77  ASN 77  77  77  ASN ASN H . n 
A 1 78  ALA 78  78  78  ALA ALA H . n 
A 1 79  LYS 79  79  79  LYS LYS H . n 
A 1 80  ASN 80  80  80  ASN ASN H . n 
A 1 81  THR 81  81  81  THR THR H . n 
A 1 82  LEU 82  82  82  LEU LEU H . n 
A 1 83  TYR 83  83  83  TYR TYR H . n 
A 1 84  LEU 84  84  84  LEU LEU H . n 
A 1 85  GLU 85  85  ?   ?   ?   H . n 
A 1 86  MET 86  86  ?   ?   ?   H . n 
A 1 87  SER 87  87  ?   ?   ?   H . n 
A 1 88  SER 88  88  ?   ?   ?   H . n 
A 1 89  LEU 89  89  ?   ?   ?   H . n 
A 1 90  ARG 90  90  ?   ?   ?   H . n 
A 1 91  SER 91  91  ?   ?   ?   H . n 
A 1 92  GLU 92  92  ?   ?   ?   H . n 
A 1 93  ASP 93  93  ?   ?   ?   H . n 
A 1 94  THR 94  94  ?   ?   ?   H . n 
A 1 95  ALA 95  95  ?   ?   ?   H . n 
A 1 96  MET 96  96  ?   ?   ?   H . n 
A 1 97  TYR 97  97  ?   ?   ?   H . n 
A 1 98  TYR 98  98  98  TYR TYR H . n 
A 1 99  CYS 99  99  99  CYS CYS H . n 
A 1 100 ALA 100 100 100 ALA ALA H . n 
A 1 101 ARG 101 101 101 ARG ARG H . n 
A 1 102 GLN 102 102 102 GLN GLN H . n 
A 1 103 ASN 103 103 103 ASN ASN H . n 
A 1 104 PHE 104 104 104 PHE PHE H . n 
A 1 105 ASP 105 105 105 ASP ASP H . n 
A 1 106 SER 106 106 106 SER SER H . n 
A 1 107 SER 107 107 107 SER SER H . n 
A 1 108 PHE 108 108 108 PHE PHE H . n 
A 1 109 TYR 109 109 109 TYR TYR H . n 
A 1 110 PHE 110 110 110 PHE PHE H . n 
A 1 111 ASP 111 111 111 ASP ASP H . n 
A 1 112 TYR 112 112 112 TYR TYR H . n 
A 1 113 TRP 113 113 113 TRP TRP H . n 
A 1 114 GLY 114 114 114 GLY GLY H . n 
A 1 115 ARG 115 115 115 ARG ARG H . n 
A 1 116 GLY 116 116 ?   ?   ?   H . n 
A 1 117 THR 117 117 ?   ?   ?   H . n 
A 1 118 THR 118 118 ?   ?   ?   H . n 
A 1 119 LEU 119 119 ?   ?   ?   H . n 
A 1 120 THR 120 120 ?   ?   ?   H . n 
A 1 121 VAL 121 121 ?   ?   ?   H . n 
A 1 122 SER 122 122 ?   ?   ?   H . n 
A 1 123 SER 123 123 ?   ?   ?   H . n 
A 1 124 ALA 124 124 ?   ?   ?   H . n 
B 2 1   MET 1   0   ?   ?   ?   c . n 
B 2 2   ALA 2   1   1   ALA ALA c . n 
B 2 3   LYS 3   2   2   LYS LYS c . n 
B 2 4   LEU 4   3   3   LEU LEU c . n 
B 2 5   GLU 5   4   4   GLU GLU c . n 
B 2 6   THR 6   5   5   THR THR c . n 
B 2 7   VAL 7   6   6   VAL VAL c . n 
B 2 8   THR 8   7   7   THR THR c . n 
B 2 9   LEU 9   8   8   LEU LEU c . n 
B 2 10  GLY 10  9   9   GLY GLY c . n 
B 2 11  ASN 11  10  10  ASN ASN c . n 
B 2 12  ILE 12  11  11  ILE ILE c . n 
B 2 13  GLY 13  12  12  GLY GLY c . n 
B 2 14  LYS 14  13  13  LYS LYS c . n 
B 2 15  ASP 15  14  14  ASP ASP c . n 
B 2 16  GLY 16  15  15  GLY GLY c . n 
B 2 17  LYS 17  16  16  LYS LYS c . n 
B 2 18  GLN 18  17  17  GLN GLN c . n 
B 2 19  THR 19  18  18  THR THR c . n 
B 2 20  LEU 20  19  19  LEU LEU c . n 
B 2 21  VAL 21  20  20  VAL VAL c . n 
B 2 22  LEU 22  21  21  LEU LEU c . n 
B 2 23  ASN 23  22  22  ASN ASN c . n 
B 2 24  PRO 24  23  23  PRO PRO c . n 
B 2 25  ARG 25  24  24  ARG ARG c . n 
B 2 26  GLY 26  25  25  GLY GLY c . n 
B 2 27  VAL 27  26  26  VAL VAL c . n 
B 2 28  ASN 28  27  27  ASN ASN c . n 
B 2 29  PRO 29  28  28  PRO PRO c . n 
B 2 30  THR 30  29  29  THR THR c . n 
B 2 31  ASN 31  30  30  ASN ASN c . n 
B 2 32  GLY 32  31  31  GLY GLY c . n 
B 2 33  VAL 33  32  32  VAL VAL c . n 
B 2 34  ALA 34  33  33  ALA ALA c . n 
B 2 35  SER 35  34  34  SER SER c . n 
B 2 36  LEU 36  35  35  LEU LEU c . n 
B 2 37  SER 37  36  36  SER SER c . n 
B 2 38  GLN 38  37  37  GLN GLN c . n 
B 2 39  ALA 39  38  38  ALA ALA c . n 
B 2 40  GLY 40  39  39  GLY GLY c . n 
B 2 41  ALA 41  40  40  ALA ALA c . n 
B 2 42  VAL 42  41  41  VAL VAL c . n 
B 2 43  PRO 43  42  42  PRO PRO c . n 
B 2 44  ALA 44  43  43  ALA ALA c . n 
B 2 45  LEU 45  44  44  LEU LEU c . n 
B 2 46  GLU 46  45  45  GLU GLU c . n 
B 2 47  LYS 47  46  46  LYS LYS c . n 
B 2 48  ARG 48  47  47  ARG ARG c . n 
B 2 49  VAL 49  48  48  VAL VAL c . n 
B 2 50  THR 50  49  49  THR THR c . n 
B 2 51  VAL 51  50  50  VAL VAL c . n 
B 2 52  SER 52  51  51  SER SER c . n 
B 2 53  VAL 53  52  52  VAL VAL c . n 
B 2 54  SER 54  53  53  SER SER c . n 
B 2 55  GLN 55  54  54  GLN GLN c . n 
B 2 56  PRO 56  55  55  PRO PRO c . n 
B 2 57  SER 57  56  ?   ?   ?   c . n 
B 2 58  ARG 58  57  ?   ?   ?   c . n 
B 2 59  ASN 59  58  ?   ?   ?   c . n 
B 2 60  ARG 60  59  ?   ?   ?   c . n 
B 2 61  LYS 61  60  60  LYS LYS c . n 
B 2 62  ASN 62  61  61  ASN ASN c . n 
B 2 63  TYR 63  62  62  TYR TYR c . n 
B 2 64  LYS 64  63  63  LYS LYS c . n 
B 2 65  VAL 65  64  64  VAL VAL c . n 
B 2 66  GLN 66  65  65  GLN GLN c . n 
B 2 67  VAL 67  66  66  VAL VAL c . n 
B 2 68  LYS 68  67  67  LYS LYS c . n 
B 2 69  ILE 69  68  68  ILE ILE c . n 
B 2 70  GLN 70  69  69  GLN GLN c . n 
B 2 71  ASN 71  70  70  ASN ASN c . n 
B 2 72  PRO 72  71  71  PRO PRO c . n 
B 2 73  THR 73  72  72  THR THR c . n 
B 2 74  ALA 74  73  73  ALA ALA c . n 
B 2 75  CYS 75  74  74  CYS CYS c . n 
B 2 76  THR 76  75  75  THR THR c . n 
B 2 77  ALA 77  76  76  ALA ALA c . n 
B 2 78  ASN 78  77  77  ASN ASN c . n 
B 2 79  GLY 79  78  78  GLY GLY c . n 
B 2 80  SER 80  79  79  SER SER c . n 
B 2 81  CYS 81  80  80  CYS CYS c . n 
B 2 82  ASP 82  81  81  ASP ASP c . n 
B 2 83  PRO 83  82  82  PRO PRO c . n 
B 2 84  SER 84  83  83  SER SER c . n 
B 2 85  VAL 85  84  84  VAL VAL c . n 
B 2 86  THR 86  85  85  THR THR c . n 
B 2 87  ARG 87  86  86  ARG ARG c . n 
B 2 88  GLN 88  87  87  GLN GLN c . n 
B 2 89  ALA 89  88  88  ALA ALA c . n 
B 2 90  TYR 90  89  89  TYR TYR c . n 
B 2 91  ALA 91  90  90  ALA ALA c . n 
B 2 92  ASP 92  91  91  ASP ASP c . n 
B 2 93  VAL 93  92  92  VAL VAL c . n 
B 2 94  THR 94  93  93  THR THR c . n 
B 2 95  PHE 95  94  94  PHE PHE c . n 
B 2 96  SER 96  95  95  SER SER c . n 
B 2 97  PHE 97  96  96  PHE PHE c . n 
B 2 98  THR 98  97  97  THR THR c . n 
B 2 99  GLN 99  98  98  GLN GLN c . n 
B 2 100 TYR 100 99  99  TYR TYR c . n 
B 2 101 SER 101 100 100 SER SER c . n 
B 2 102 THR 102 101 101 THR THR c . n 
B 2 103 ASP 103 102 102 ASP ASP c . n 
B 2 104 GLU 104 103 103 GLU GLU c . n 
B 2 105 GLU 105 104 104 GLU GLU c . n 
B 2 106 ARG 106 105 105 ARG ARG c . n 
B 2 107 ALA 107 106 106 ALA ALA c . n 
B 2 108 PHE 108 107 107 PHE PHE c . n 
B 2 109 VAL 109 108 108 VAL VAL c . n 
B 2 110 ARG 110 109 109 ARG ARG c . n 
B 2 111 THR 111 110 110 THR THR c . n 
B 2 112 GLU 112 111 111 GLU GLU c . n 
B 2 113 LEU 113 112 112 LEU LEU c . n 
B 2 114 ALA 114 113 113 ALA ALA c . n 
B 2 115 ALA 115 114 114 ALA ALA c . n 
B 2 116 LEU 116 115 115 LEU LEU c . n 
B 2 117 LEU 117 116 116 LEU LEU c . n 
B 2 118 ALA 118 117 117 ALA ALA c . n 
B 2 119 SER 119 118 118 SER SER c . n 
B 2 120 PRO 120 119 119 PRO PRO c . n 
B 2 121 LEU 121 120 120 LEU LEU c . n 
B 2 122 LEU 122 121 121 LEU LEU c . n 
B 2 123 ILE 123 122 122 ILE ILE c . n 
B 2 124 ASP 124 123 123 ASP ASP c . n 
B 2 125 ALA 125 124 124 ALA ALA c . n 
B 2 126 ILE 126 125 125 ILE ILE c . n 
B 2 127 ASP 127 126 126 ASP ASP c . n 
B 2 128 GLN 128 127 127 GLN GLN c . n 
B 2 129 LEU 129 128 128 LEU LEU c . n 
B 2 130 ASN 130 129 129 ASN ASN c . n 
B 2 131 PRO 131 130 130 PRO PRO c . n 
B 2 132 ALA 132 131 131 ALA ALA c . n 
B 2 133 TYR 133 132 ?   ?   ?   c . n 
C 2 1   MET 1   0   ?   ?   ?   C . n 
C 2 2   ALA 2   1   1   ALA ALA C . n 
C 2 3   LYS 3   2   2   LYS LYS C . n 
C 2 4   LEU 4   3   3   LEU LEU C . n 
C 2 5   GLU 5   4   4   GLU GLU C . n 
C 2 6   THR 6   5   5   THR THR C . n 
C 2 7   VAL 7   6   6   VAL VAL C . n 
C 2 8   THR 8   7   7   THR THR C . n 
C 2 9   LEU 9   8   8   LEU LEU C . n 
C 2 10  GLY 10  9   9   GLY GLY C . n 
C 2 11  ASN 11  10  10  ASN ASN C . n 
C 2 12  ILE 12  11  11  ILE ILE C . n 
C 2 13  GLY 13  12  12  GLY GLY C . n 
C 2 14  LYS 14  13  13  LYS LYS C . n 
C 2 15  ASP 15  14  14  ASP ASP C . n 
C 2 16  GLY 16  15  15  GLY GLY C . n 
C 2 17  LYS 17  16  16  LYS LYS C . n 
C 2 18  GLN 18  17  17  GLN GLN C . n 
C 2 19  THR 19  18  18  THR THR C . n 
C 2 20  LEU 20  19  19  LEU LEU C . n 
C 2 21  VAL 21  20  20  VAL VAL C . n 
C 2 22  LEU 22  21  21  LEU LEU C . n 
C 2 23  ASN 23  22  22  ASN ASN C . n 
C 2 24  PRO 24  23  23  PRO PRO C . n 
C 2 25  ARG 25  24  24  ARG ARG C . n 
C 2 26  GLY 26  25  25  GLY GLY C . n 
C 2 27  VAL 27  26  26  VAL VAL C . n 
C 2 28  ASN 28  27  27  ASN ASN C . n 
C 2 29  PRO 29  28  28  PRO PRO C . n 
C 2 30  THR 30  29  29  THR THR C . n 
C 2 31  ASN 31  30  30  ASN ASN C . n 
C 2 32  GLY 32  31  31  GLY GLY C . n 
C 2 33  VAL 33  32  32  VAL VAL C . n 
C 2 34  ALA 34  33  33  ALA ALA C . n 
C 2 35  SER 35  34  34  SER SER C . n 
C 2 36  LEU 36  35  35  LEU LEU C . n 
C 2 37  SER 37  36  36  SER SER C . n 
C 2 38  GLN 38  37  37  GLN GLN C . n 
C 2 39  ALA 39  38  38  ALA ALA C . n 
C 2 40  GLY 40  39  39  GLY GLY C . n 
C 2 41  ALA 41  40  40  ALA ALA C . n 
C 2 42  VAL 42  41  41  VAL VAL C . n 
C 2 43  PRO 43  42  42  PRO PRO C . n 
C 2 44  ALA 44  43  43  ALA ALA C . n 
C 2 45  LEU 45  44  44  LEU LEU C . n 
C 2 46  GLU 46  45  45  GLU GLU C . n 
C 2 47  LYS 47  46  46  LYS LYS C . n 
C 2 48  ARG 48  47  47  ARG ARG C . n 
C 2 49  VAL 49  48  48  VAL VAL C . n 
C 2 50  THR 50  49  49  THR THR C . n 
C 2 51  VAL 51  50  50  VAL VAL C . n 
C 2 52  SER 52  51  51  SER SER C . n 
C 2 53  VAL 53  52  52  VAL VAL C . n 
C 2 54  SER 54  53  53  SER SER C . n 
C 2 55  GLN 55  54  54  GLN GLN C . n 
C 2 56  PRO 56  55  55  PRO PRO C . n 
C 2 57  SER 57  56  ?   ?   ?   C . n 
C 2 58  ARG 58  57  ?   ?   ?   C . n 
C 2 59  ASN 59  58  ?   ?   ?   C . n 
C 2 60  ARG 60  59  ?   ?   ?   C . n 
C 2 61  LYS 61  60  60  LYS LYS C . n 
C 2 62  ASN 62  61  61  ASN ASN C . n 
C 2 63  TYR 63  62  62  TYR TYR C . n 
C 2 64  LYS 64  63  63  LYS LYS C . n 
C 2 65  VAL 65  64  64  VAL VAL C . n 
C 2 66  GLN 66  65  65  GLN GLN C . n 
C 2 67  VAL 67  66  66  VAL VAL C . n 
C 2 68  LYS 68  67  67  LYS LYS C . n 
C 2 69  ILE 69  68  68  ILE ILE C . n 
C 2 70  GLN 70  69  69  GLN GLN C . n 
C 2 71  ASN 71  70  70  ASN ASN C . n 
C 2 72  PRO 72  71  71  PRO PRO C . n 
C 2 73  THR 73  72  72  THR THR C . n 
C 2 74  ALA 74  73  73  ALA ALA C . n 
C 2 75  CYS 75  74  74  CYS CYS C . n 
C 2 76  THR 76  75  75  THR THR C . n 
C 2 77  ALA 77  76  76  ALA ALA C . n 
C 2 78  ASN 78  77  77  ASN ASN C . n 
C 2 79  GLY 79  78  78  GLY GLY C . n 
C 2 80  SER 80  79  79  SER SER C . n 
C 2 81  CYS 81  80  80  CYS CYS C . n 
C 2 82  ASP 82  81  81  ASP ASP C . n 
C 2 83  PRO 83  82  82  PRO PRO C . n 
C 2 84  SER 84  83  83  SER SER C . n 
C 2 85  VAL 85  84  84  VAL VAL C . n 
C 2 86  THR 86  85  85  THR THR C . n 
C 2 87  ARG 87  86  86  ARG ARG C . n 
C 2 88  GLN 88  87  87  GLN GLN C . n 
C 2 89  ALA 89  88  88  ALA ALA C . n 
C 2 90  TYR 90  89  89  TYR TYR C . n 
C 2 91  ALA 91  90  90  ALA ALA C . n 
C 2 92  ASP 92  91  91  ASP ASP C . n 
C 2 93  VAL 93  92  92  VAL VAL C . n 
C 2 94  THR 94  93  93  THR THR C . n 
C 2 95  PHE 95  94  94  PHE PHE C . n 
C 2 96  SER 96  95  95  SER SER C . n 
C 2 97  PHE 97  96  96  PHE PHE C . n 
C 2 98  THR 98  97  97  THR THR C . n 
C 2 99  GLN 99  98  98  GLN GLN C . n 
C 2 100 TYR 100 99  99  TYR TYR C . n 
C 2 101 SER 101 100 100 SER SER C . n 
C 2 102 THR 102 101 101 THR THR C . n 
C 2 103 ASP 103 102 102 ASP ASP C . n 
C 2 104 GLU 104 103 103 GLU GLU C . n 
C 2 105 GLU 105 104 104 GLU GLU C . n 
C 2 106 ARG 106 105 105 ARG ARG C . n 
C 2 107 ALA 107 106 106 ALA ALA C . n 
C 2 108 PHE 108 107 107 PHE PHE C . n 
C 2 109 VAL 109 108 108 VAL VAL C . n 
C 2 110 ARG 110 109 109 ARG ARG C . n 
C 2 111 THR 111 110 110 THR THR C . n 
C 2 112 GLU 112 111 111 GLU GLU C . n 
C 2 113 LEU 113 112 112 LEU LEU C . n 
C 2 114 ALA 114 113 113 ALA ALA C . n 
C 2 115 ALA 115 114 114 ALA ALA C . n 
C 2 116 LEU 116 115 115 LEU LEU C . n 
C 2 117 LEU 117 116 116 LEU LEU C . n 
C 2 118 ALA 118 117 117 ALA ALA C . n 
C 2 119 SER 119 118 118 SER SER C . n 
C 2 120 PRO 120 119 119 PRO PRO C . n 
C 2 121 LEU 121 120 120 LEU LEU C . n 
C 2 122 LEU 122 121 121 LEU LEU C . n 
C 2 123 ILE 123 122 122 ILE ILE C . n 
C 2 124 ASP 124 123 123 ASP ASP C . n 
C 2 125 ALA 125 124 124 ALA ALA C . n 
C 2 126 ILE 126 125 125 ILE ILE C . n 
C 2 127 ASP 127 126 126 ASP ASP C . n 
C 2 128 GLN 128 127 127 GLN GLN C . n 
C 2 129 LEU 129 128 128 LEU LEU C . n 
C 2 130 ASN 130 129 129 ASN ASN C . n 
C 2 131 PRO 131 130 130 PRO PRO C . n 
C 2 132 ALA 132 131 131 ALA ALA C . n 
C 2 133 TYR 133 132 ?   ?   ?   C . n 
D 3 1   VAL 1   1   ?   ?   ?   L . n 
D 3 2   HIS 2   2   ?   ?   ?   L . n 
D 3 3   SER 3   3   ?   ?   ?   L . n 
D 3 4   GLU 4   4   ?   ?   ?   L . n 
D 3 5   THR 5   5   ?   ?   ?   L . n 
D 3 6   THR 6   6   ?   ?   ?   L . n 
D 3 7   VAL 7   7   7   VAL VAL L . n 
D 3 8   THR 8   8   8   THR THR L . n 
D 3 9   GLN 9   9   9   GLN GLN L . n 
D 3 10  SER 10  10  10  SER SER L . n 
D 3 11  PRO 11  11  11  PRO PRO L . n 
D 3 12  ALA 12  12  12  ALA ALA L . n 
D 3 13  SER 13  13  13  SER SER L . n 
D 3 14  LEU 14  14  14  LEU LEU L . n 
D 3 15  SEP 15  15  15  SEP SEP L . n 
D 3 16  VAL 16  16  16  VAL VAL L . n 
D 3 17  ALA 17  17  17  ALA ALA L . n 
D 3 18  THR 18  18  18  THR THR L . n 
D 3 19  GLY 19  19  19  GLY GLY L . n 
D 3 20  GLU 20  20  20  GLU GLU L . n 
D 3 21  LYS 21  21  21  LYS LYS L . n 
D 3 22  VAL 22  22  22  VAL VAL L . n 
D 3 23  THR 23  23  23  THR THR L . n 
D 3 24  ILE 24  24  24  ILE ILE L . n 
D 3 25  ARG 25  25  25  ARG ARG L . n 
D 3 26  CYS 26  26  26  CYS CYS L . n 
D 3 27  ILE 27  27  27  ILE ILE L . n 
D 3 28  THR 28  28  28  THR THR L . n 
D 3 29  SER 29  29  29  SER SER L . n 
D 3 30  THR 30  30  30  THR THR L . n 
D 3 31  ASP 31  31  31  ASP ASP L . n 
D 3 32  ILE 32  32  32  ILE ILE L . n 
D 3 33  ASP 33  33  33  ASP ASP L . n 
D 3 34  ASP 34  34  34  ASP ASP L . n 
D 3 35  ASP 35  35  35  ASP ASP L . n 
D 3 36  MET 36  36  36  MET MET L . n 
D 3 37  ASN 37  37  37  ASN ASN L . n 
D 3 38  TRP 38  38  38  TRP TRP L . n 
D 3 39  TYR 39  39  39  TYR TYR L . n 
D 3 40  GLN 40  40  40  GLN GLN L . n 
D 3 41  GLN 41  41  41  GLN GLN L . n 
D 3 42  LYS 42  42  42  LYS LYS L . n 
D 3 43  PRO 43  43  43  PRO PRO L . n 
D 3 44  GLY 44  44  44  GLY GLY L . n 
D 3 45  GLU 45  45  45  GLU GLU L . n 
D 3 46  PRO 46  46  46  PRO PRO L . n 
D 3 47  PRO 47  47  47  PRO PRO L . n 
D 3 48  LYS 48  48  48  LYS LYS L . n 
D 3 49  LEU 49  49  49  LEU LEU L . n 
D 3 50  LEU 50  50  50  LEU LEU L . n 
D 3 51  ILE 51  51  51  ILE ILE L . n 
D 3 52  SER 52  52  52  SER SER L . n 
D 3 53  GLU 53  53  53  GLU GLU L . n 
D 3 54  GLY 54  54  54  GLY GLY L . n 
D 3 55  ASN 55  55  55  ASN ASN L . n 
D 3 56  THR 56  56  56  THR THR L . n 
D 3 57  LEU 57  57  57  LEU LEU L . n 
D 3 58  ARG 58  58  58  ARG ARG L . n 
D 3 59  PRO 59  59  59  PRO PRO L . n 
D 3 60  GLY 60  60  60  GLY GLY L . n 
D 3 61  VAL 61  61  61  VAL VAL L . n 
D 3 62  PRO 62  62  62  PRO PRO L . n 
D 3 63  SER 63  63  63  SER SER L . n 
D 3 64  ARG 64  64  64  ARG ARG L . n 
D 3 65  PHE 65  65  65  PHE PHE L . n 
D 3 66  SER 66  66  66  SER SER L . n 
D 3 67  SER 67  67  67  SER SER L . n 
D 3 68  SER 68  68  68  SER SER L . n 
D 3 69  GLY 69  69  69  GLY GLY L . n 
D 3 70  TYR 70  70  70  TYR TYR L . n 
D 3 71  GLY 71  71  71  GLY GLY L . n 
D 3 72  THR 72  72  72  THR THR L . n 
D 3 73  ASP 73  73  73  ASP ASP L . n 
D 3 74  PHE 74  74  74  PHE PHE L . n 
D 3 75  VAL 75  75  75  VAL VAL L . n 
D 3 76  PHE 76  76  76  PHE PHE L . n 
D 3 77  THR 77  77  77  THR THR L . n 
D 3 78  ILE 78  78  78  ILE ILE L . n 
D 3 79  GLU 79  79  79  GLU GLU L . n 
D 3 80  ASN 80  80  80  ASN ASN L . n 
D 3 81  THR 81  81  81  THR THR L . n 
D 3 82  LEU 82  82  82  LEU LEU L . n 
D 3 83  SER 83  83  83  SER SER L . n 
D 3 84  GLU 84  84  84  GLU GLU L . n 
D 3 85  ASP 85  85  85  ASP ASP L . n 
D 3 86  VAL 86  86  86  VAL VAL L . n 
D 3 87  ALA 87  87  87  ALA ALA L . n 
D 3 88  ASP 88  88  88  ASP ASP L . n 
D 3 89  TYR 89  89  89  TYR TYR L . n 
D 3 90  TYR 90  90  90  TYR TYR L . n 
D 3 91  CYS 91  91  91  CYS CYS L . n 
D 3 92  LEU 92  92  92  LEU LEU L . n 
D 3 93  GLN 93  93  93  GLN GLN L . n 
D 3 94  SER 94  94  94  SER SER L . n 
D 3 95  ASP 95  95  95  ASP ASP L . n 
D 3 96  ASN 96  96  96  ASN ASN L . n 
D 3 97  MET 97  97  97  MET MET L . n 
D 3 98  PRO 98  98  98  PRO PRO L . n 
D 3 99  LEU 99  99  99  LEU LEU L . n 
D 3 100 THR 100 100 100 THR THR L . n 
D 3 101 PHE 101 101 ?   ?   ?   L . n 
D 3 102 GLY 102 102 ?   ?   ?   L . n 
D 3 103 ALA 103 103 ?   ?   ?   L . n 
D 3 104 GLY 104 104 ?   ?   ?   L . n 
D 3 105 THR 105 105 ?   ?   ?   L . n 
D 3 106 LYS 106 106 ?   ?   ?   L . n 
D 3 107 LEU 107 107 ?   ?   ?   L . n 
D 3 108 GLU 108 108 ?   ?   ?   L . n 
D 3 109 ILE 109 109 ?   ?   ?   L . n 
D 3 110 LYS 110 110 ?   ?   ?   L . n 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8W5E 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8W5E 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8W5E 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     8W5E 
_struct.title                        'Cryo-EM structure of Qb-Ab4' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8W5E 
_struct_keywords.text            'Qb, Antibody, cryo-EM, IMMUNE SYSTEM' 
_struct_keywords.pdbx_keywords   'IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 2 ? 
D N N 3 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 8W5E     8W5E   ? 1 ? 1 
2 UNP A1_BPQBE Q8LTE1 ? 2 
;MAKLETVTLGNIGKDGKQTLVLNPRGVNPTNGVASLSQAGAVPALEKRVTVSVSQPSRNRKNYKVQVKIQNPTACTANGS
CDPSVTRQAYADVTFSFTQYSTDEERAFVRTELAALLASPLLIDAIDQLNPAY
;
1 
3 PDB 8W5E     8W5E   ? 3 ? 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8W5E H 1 ? 124 ? 8W5E   1 ? 124 ? 1 124 
2 2 8W5E c 1 ? 133 ? Q8LTE1 1 ? 133 ? 0 132 
3 2 8W5E C 1 ? 133 ? Q8LTE1 1 ? 133 ? 0 132 
4 3 8W5E L 1 ? 110 ? 8W5E   1 ? 110 ? 1 110 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 AA1 THR B 102 ? LEU B 117 ? THR c 101 LEU c 116 1 ? 16 
HELX_P HELX_P2 AA2 LEU B 121 ? ASP B 127 ? LEU c 120 ASP c 126 1 ? 7  
HELX_P HELX_P3 AA3 THR C 102 ? LEU C 117 ? THR C 101 LEU C 116 1 ? 16 
HELX_P HELX_P4 AA4 LEU C 121 ? ASP C 127 ? LEU C 120 ASP C 126 1 ? 7  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ?    ? A CYS 25 SG ? ? ? 1_555 A CYS 99 SG ? ? H CYS 25 H CYS 99 1_555 ? ? ? ? ? ? ? 2.033 ? ? 
disulf2 disulf ?    ? D CYS 26 SG ? ? ? 1_555 D CYS 91 SG ? ? L CYS 26 L CYS 91 1_555 ? ? ? ? ? ? ? 2.042 ? ? 
covale1 covale both ? A ILE 73 C  ? ? ? 1_555 A SEP 74 N  ? ? H ILE 73 H SEP 74 1_555 ? ? ? ? ? ? ? 1.327 ? ? 
covale2 covale both ? A SEP 74 C  ? ? ? 1_555 A ARG 75 N  ? ? H SEP 74 H ARG 75 1_555 ? ? ? ? ? ? ? 1.328 ? ? 
covale3 covale both ? D LEU 14 C  ? ? ? 1_555 D SEP 15 N  ? ? L LEU 14 L SEP 15 1_555 ? ? ? ? ? ? ? 1.329 ? ? 
covale4 covale both ? D SEP 15 C  ? ? ? 1_555 D VAL 16 N  ? ? L SEP 15 L VAL 16 1_555 ? ? ? ? ? ? ? 1.333 ? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 SEP A 74 ? .   . .  . SEP H 74 ? 1_555 .   . .  . .     .  .  SER 1 SEP Phosphorylation 'Named protein modification' 
2 SEP D 15 ? .   . .  . SEP L 15 ? 1_555 .   . .  . .     .  .  SER 1 SEP Phosphorylation 'Named protein modification' 
3 CYS A 25 ? CYS A 99 ? CYS H 25 ? 1_555 CYS H 99 ? 1_555 SG SG .   . .   None            'Disulfide bridge'           
4 CYS D 26 ? CYS D 91 ? CYS L 26 ? 1_555 CYS L 91 ? 1_555 SG SG .   . .   None            'Disulfide bridge'           
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 3 ? 
AA3 ? 5 ? 
AA4 ? 5 ? 
AA5 ? 4 ? 
AA6 ? 3 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA3 4 5 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA4 4 5 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 LEU A 7   ? SER A 10  ? LEU H 7   SER H 10  
AA1 2 LEU A 23  ? ALA A 27  ? LEU H 23  ALA H 27  
AA1 3 ASN A 80  ? TYR A 83  ? ASN H 80  TYR H 83  
AA1 4 THR A 72  ? ARG A 75  ? THR H 72  ARG H 75  
AA2 1 MET A 37  ? TRP A 39  ? MET H 37  TRP H 39  
AA2 2 CYS A 99  ? GLN A 102 ? CYS H 99  GLN H 102 
AA2 3 PHE A 110 ? TYR A 112 ? PHE H 110 TYR H 112 
AA3 1 ASN B 23  ? ASN B 28  ? ASN c 22  ASN c 27  
AA3 2 VAL B 33  ? SER B 37  ? VAL c 32  SER c 36  
AA3 3 ARG B 48  ? VAL B 53  ? ARG c 47  VAL c 52  
AA3 4 VAL B 65  ? CYS B 75  ? VAL c 64  CYS c 74  
AA3 5 SER B 84  ? PHE B 95  ? SER c 83  PHE c 94  
AA4 1 ASN C 23  ? ASN C 28  ? ASN C 22  ASN C 27  
AA4 2 VAL C 33  ? SER C 37  ? VAL C 32  SER C 36  
AA4 3 ARG C 48  ? VAL C 53  ? ARG C 47  VAL C 52  
AA4 4 VAL C 65  ? CYS C 75  ? VAL C 64  CYS C 74  
AA4 5 SER C 84  ? PHE C 95  ? SER C 83  PHE C 94  
AA5 1 THR D 8   ? GLN D 9   ? THR L 8   GLN L 9   
AA5 2 ILE D 24  ? THR D 28  ? ILE L 24  THR L 28  
AA5 3 ASP D 73  ? THR D 77  ? ASP L 73  THR L 77  
AA5 4 SER D 66  ? TYR D 70  ? SER L 66  TYR L 70  
AA6 1 LYS D 48  ? LEU D 49  ? LYS L 48  LEU L 49  
AA6 2 MET D 36  ? GLN D 41  ? MET L 36  GLN L 41  
AA6 3 ASP D 88  ? GLN D 93  ? ASP L 88  GLN L 93  
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N SER A 10  ? N SER H 10  O SER A 24  ? O SER H 24  
AA1 2 3 N LEU A 23  ? N LEU H 23  O TYR A 83  ? O TYR H 83  
AA1 3 4 O LEU A 82  ? O LEU H 82  N ILE A 73  ? N ILE H 73  
AA2 1 2 N ALA A 38  ? N ALA H 38  O ALA A 100 ? O ALA H 100 
AA2 2 3 N ARG A 101 ? N ARG H 101 O TYR A 112 ? O TYR H 112 
AA3 1 2 N ASN B 23  ? N ASN c 22  O SER B 37  ? O SER c 36  
AA3 2 3 N LEU B 36  ? N LEU c 35  O VAL B 49  ? O VAL c 48  
AA3 3 4 N THR B 50  ? N THR c 49  O LYS B 68  ? O LYS c 67  
AA3 4 5 N VAL B 65  ? N VAL c 64  O PHE B 95  ? O PHE c 94  
AA4 1 2 N ASN C 23  ? N ASN C 22  O SER C 37  ? O SER C 36  
AA4 2 3 N LEU C 36  ? N LEU C 35  O VAL C 49  ? O VAL C 48  
AA4 3 4 N THR C 50  ? N THR C 49  O LYS C 68  ? O LYS C 67  
AA4 4 5 N VAL C 65  ? N VAL C 64  O PHE C 95  ? O PHE C 94  
AA5 1 2 N GLN D 9   ? N GLN L 9   O ILE D 27  ? O ILE L 27  
AA5 2 3 N ILE D 24  ? N ILE L 24  O PHE D 76  ? O PHE L 76  
AA5 3 4 O VAL D 75  ? O VAL L 75  N SER D 68  ? N SER L 68  
AA6 1 2 O LYS D 48  ? O LYS L 48  N GLN D 40  ? N GLN L 40  
AA6 2 3 N GLN D 41  ? N GLN L 41  O ASP D 88  ? O ASP L 88  
# 
_pdbx_entry_details.entry_id                   8W5E 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_close_contact.id               1 
_pdbx_validate_close_contact.PDB_model_num    1 
_pdbx_validate_close_contact.auth_atom_id_1   OE2 
_pdbx_validate_close_contact.auth_asym_id_1   H 
_pdbx_validate_close_contact.auth_comp_id_1   GLU 
_pdbx_validate_close_contact.auth_seq_id_1    9 
_pdbx_validate_close_contact.PDB_ins_code_1   ? 
_pdbx_validate_close_contact.label_alt_id_1   ? 
_pdbx_validate_close_contact.auth_atom_id_2   C 
_pdbx_validate_close_contact.auth_asym_id_2   H 
_pdbx_validate_close_contact.auth_comp_id_2   ARG 
_pdbx_validate_close_contact.auth_seq_id_2    115 
_pdbx_validate_close_contact.PDB_ins_code_2   ? 
_pdbx_validate_close_contact.label_alt_id_2   ? 
_pdbx_validate_close_contact.dist             2.16 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 CA L LEU 49 ? ? CB L LEU 49 ? ? CG L LEU 49 ? ? 130.12 115.30 14.82 2.30 N 
2 1 CA L LEU 92 ? ? CB L LEU 92 ? ? CG L LEU 92 ? ? 129.36 115.30 14.06 2.30 N 
3 1 CA L LEU 99 ? ? CB L LEU 99 ? ? CG L LEU 99 ? ? 129.54 115.30 14.24 2.30 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 SER H 28 ? ? -142.06 20.30   
2  1 THR H 31 ? ? 71.39   -9.17   
3  1 PHE H 32 ? ? 66.41   -10.54  
4  1 ASP H 34 ? ? 70.57   -6.59   
5  1 TYR H 59 ? ? -95.53  -63.85  
6  1 GLU H 76 ? ? -93.03  52.25   
7  1 LYS c 13 ? ? 67.97   -18.12  
8  1 ASP c 14 ? ? -141.91 -13.07  
9  1 LYS C 13 ? ? 67.93   -18.05  
10 1 ASP C 14 ? ? -141.95 -13.05  
11 1 SEP L 15 ? ? -144.10 -31.98  
12 1 VAL L 16 ? ? 57.34   -76.95  
13 1 MET L 36 ? ? -160.97 114.79  
14 1 LEU L 50 ? ? -150.73 -148.95 
15 1 ILE L 51 ? ? -54.34  16.12   
16 1 SER L 52 ? ? -40.36  158.16  
17 1 ASN L 55 ? ? -141.28 46.78   
18 1 LEU L 57 ? ? 59.11   71.13   
19 1 ILE L 78 ? ? -113.89 -78.66  
20 1 GLU L 79 ? ? 178.13  158.32  
21 1 THR L 81 ? ? 37.43   47.53   
22 1 ASN L 96 ? ? 60.32   75.95   
23 1 MET L 97 ? ? -31.21  -38.68  
24 1 LEU L 99 ? ? 57.53   18.23   
# 
_pdbx_validate_peptide_omega.id               1 
_pdbx_validate_peptide_omega.PDB_model_num    1 
_pdbx_validate_peptide_omega.auth_comp_id_1   LEU 
_pdbx_validate_peptide_omega.auth_asym_id_1   L 
_pdbx_validate_peptide_omega.auth_seq_id_1    50 
_pdbx_validate_peptide_omega.PDB_ins_code_1   ? 
_pdbx_validate_peptide_omega.label_alt_id_1   ? 
_pdbx_validate_peptide_omega.auth_comp_id_2   ILE 
_pdbx_validate_peptide_omega.auth_asym_id_2   L 
_pdbx_validate_peptide_omega.auth_seq_id_2    51 
_pdbx_validate_peptide_omega.PDB_ins_code_2   ? 
_pdbx_validate_peptide_omega.label_alt_id_2   ? 
_pdbx_validate_peptide_omega.omega            -149.45 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          8W5E 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    8W5E 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.8 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               123614 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Complex of Qb-Ab4' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2, 3' 
# 
_em_imaging.entry_id                        8W5E 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             1500 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              8W5E 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                8W5E 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 H VAL 1   ? A VAL 1   
2  1 Y 1 H HIS 2   ? A HIS 2   
3  1 Y 1 H SER 3   ? A SER 3   
4  1 Y 1 H GLU 4   ? A GLU 4   
5  1 Y 1 H GLU 85  ? A GLU 85  
6  1 Y 1 H MET 86  ? A MET 86  
7  1 Y 1 H SER 87  ? A SER 87  
8  1 Y 1 H SER 88  ? A SER 88  
9  1 Y 1 H LEU 89  ? A LEU 89  
10 1 Y 1 H ARG 90  ? A ARG 90  
11 1 Y 1 H SER 91  ? A SER 91  
12 1 Y 1 H GLU 92  ? A GLU 92  
13 1 Y 1 H ASP 93  ? A ASP 93  
14 1 Y 1 H THR 94  ? A THR 94  
15 1 Y 1 H ALA 95  ? A ALA 95  
16 1 Y 1 H MET 96  ? A MET 96  
17 1 Y 1 H TYR 97  ? A TYR 97  
18 1 Y 1 H GLY 116 ? A GLY 116 
19 1 Y 1 H THR 117 ? A THR 117 
20 1 Y 1 H THR 118 ? A THR 118 
21 1 Y 1 H LEU 119 ? A LEU 119 
22 1 Y 1 H THR 120 ? A THR 120 
23 1 Y 1 H VAL 121 ? A VAL 121 
24 1 Y 1 H SER 122 ? A SER 122 
25 1 Y 1 H SER 123 ? A SER 123 
26 1 Y 1 H ALA 124 ? A ALA 124 
27 1 Y 1 c MET 0   ? B MET 1   
28 1 Y 1 c SER 56  ? B SER 57  
29 1 Y 1 c ARG 57  ? B ARG 58  
30 1 Y 1 c ASN 58  ? B ASN 59  
31 1 Y 1 c ARG 59  ? B ARG 60  
32 1 Y 1 c TYR 132 ? B TYR 133 
33 1 Y 1 C MET 0   ? C MET 1   
34 1 Y 1 C SER 56  ? C SER 57  
35 1 Y 1 C ARG 57  ? C ARG 58  
36 1 Y 1 C ASN 58  ? C ASN 59  
37 1 Y 1 C ARG 59  ? C ARG 60  
38 1 Y 1 C TYR 132 ? C TYR 133 
39 1 Y 1 L VAL 1   ? D VAL 1   
40 1 Y 1 L HIS 2   ? D HIS 2   
41 1 Y 1 L SER 3   ? D SER 3   
42 1 Y 1 L GLU 4   ? D GLU 4   
43 1 Y 1 L THR 5   ? D THR 5   
44 1 Y 1 L THR 6   ? D THR 6   
45 1 Y 1 L PHE 101 ? D PHE 101 
46 1 Y 1 L GLY 102 ? D GLY 102 
47 1 Y 1 L ALA 103 ? D ALA 103 
48 1 Y 1 L GLY 104 ? D GLY 104 
49 1 Y 1 L THR 105 ? D THR 105 
50 1 Y 1 L LYS 106 ? D LYS 106 
51 1 Y 1 L LEU 107 ? D LEU 107 
52 1 Y 1 L GLU 108 ? D GLU 108 
53 1 Y 1 L ILE 109 ? D ILE 109 
54 1 Y 1 L LYS 110 ? D LYS 110 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SEP N    N N N 287 
SEP CA   C N S 288 
SEP CB   C N N 289 
SEP OG   O N N 290 
SEP C    C N N 291 
SEP O    O N N 292 
SEP OXT  O N N 293 
SEP P    P N N 294 
SEP O1P  O N N 295 
SEP O2P  O N N 296 
SEP O3P  O N N 297 
SEP H    H N N 298 
SEP H2   H N N 299 
SEP HA   H N N 300 
SEP HB2  H N N 301 
SEP HB3  H N N 302 
SEP HXT  H N N 303 
SEP HOP2 H N N 304 
SEP HOP3 H N N 305 
SER N    N N N 306 
SER CA   C N S 307 
SER C    C N N 308 
SER O    O N N 309 
SER CB   C N N 310 
SER OG   O N N 311 
SER OXT  O N N 312 
SER H    H N N 313 
SER H2   H N N 314 
SER HA   H N N 315 
SER HB2  H N N 316 
SER HB3  H N N 317 
SER HG   H N N 318 
SER HXT  H N N 319 
THR N    N N N 320 
THR CA   C N S 321 
THR C    C N N 322 
THR O    O N N 323 
THR CB   C N R 324 
THR OG1  O N N 325 
THR CG2  C N N 326 
THR OXT  O N N 327 
THR H    H N N 328 
THR H2   H N N 329 
THR HA   H N N 330 
THR HB   H N N 331 
THR HG1  H N N 332 
THR HG21 H N N 333 
THR HG22 H N N 334 
THR HG23 H N N 335 
THR HXT  H N N 336 
TRP N    N N N 337 
TRP CA   C N S 338 
TRP C    C N N 339 
TRP O    O N N 340 
TRP CB   C N N 341 
TRP CG   C Y N 342 
TRP CD1  C Y N 343 
TRP CD2  C Y N 344 
TRP NE1  N Y N 345 
TRP CE2  C Y N 346 
TRP CE3  C Y N 347 
TRP CZ2  C Y N 348 
TRP CZ3  C Y N 349 
TRP CH2  C Y N 350 
TRP OXT  O N N 351 
TRP H    H N N 352 
TRP H2   H N N 353 
TRP HA   H N N 354 
TRP HB2  H N N 355 
TRP HB3  H N N 356 
TRP HD1  H N N 357 
TRP HE1  H N N 358 
TRP HE3  H N N 359 
TRP HZ2  H N N 360 
TRP HZ3  H N N 361 
TRP HH2  H N N 362 
TRP HXT  H N N 363 
TYR N    N N N 364 
TYR CA   C N S 365 
TYR C    C N N 366 
TYR O    O N N 367 
TYR CB   C N N 368 
TYR CG   C Y N 369 
TYR CD1  C Y N 370 
TYR CD2  C Y N 371 
TYR CE1  C Y N 372 
TYR CE2  C Y N 373 
TYR CZ   C Y N 374 
TYR OH   O N N 375 
TYR OXT  O N N 376 
TYR H    H N N 377 
TYR H2   H N N 378 
TYR HA   H N N 379 
TYR HB2  H N N 380 
TYR HB3  H N N 381 
TYR HD1  H N N 382 
TYR HD2  H N N 383 
TYR HE1  H N N 384 
TYR HE2  H N N 385 
TYR HH   H N N 386 
TYR HXT  H N N 387 
VAL N    N N N 388 
VAL CA   C N S 389 
VAL C    C N N 390 
VAL O    O N N 391 
VAL CB   C N N 392 
VAL CG1  C N N 393 
VAL CG2  C N N 394 
VAL OXT  O N N 395 
VAL H    H N N 396 
VAL H2   H N N 397 
VAL HA   H N N 398 
VAL HB   H N N 399 
VAL HG11 H N N 400 
VAL HG12 H N N 401 
VAL HG13 H N N 402 
VAL HG21 H N N 403 
VAL HG22 H N N 404 
VAL HG23 H N N 405 
VAL HXT  H N N 406 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SEP N   CA   sing N N 275 
SEP N   H    sing N N 276 
SEP N   H2   sing N N 277 
SEP CA  CB   sing N N 278 
SEP CA  C    sing N N 279 
SEP CA  HA   sing N N 280 
SEP CB  OG   sing N N 281 
SEP CB  HB2  sing N N 282 
SEP CB  HB3  sing N N 283 
SEP OG  P    sing N N 284 
SEP C   O    doub N N 285 
SEP C   OXT  sing N N 286 
SEP OXT HXT  sing N N 287 
SEP P   O1P  doub N N 288 
SEP P   O2P  sing N N 289 
SEP P   O3P  sing N N 290 
SEP O2P HOP2 sing N N 291 
SEP O3P HOP3 sing N N 292 
SER N   CA   sing N N 293 
SER N   H    sing N N 294 
SER N   H2   sing N N 295 
SER CA  C    sing N N 296 
SER CA  CB   sing N N 297 
SER CA  HA   sing N N 298 
SER C   O    doub N N 299 
SER C   OXT  sing N N 300 
SER CB  OG   sing N N 301 
SER CB  HB2  sing N N 302 
SER CB  HB3  sing N N 303 
SER OG  HG   sing N N 304 
SER OXT HXT  sing N N 305 
THR N   CA   sing N N 306 
THR N   H    sing N N 307 
THR N   H2   sing N N 308 
THR CA  C    sing N N 309 
THR CA  CB   sing N N 310 
THR CA  HA   sing N N 311 
THR C   O    doub N N 312 
THR C   OXT  sing N N 313 
THR CB  OG1  sing N N 314 
THR CB  CG2  sing N N 315 
THR CB  HB   sing N N 316 
THR OG1 HG1  sing N N 317 
THR CG2 HG21 sing N N 318 
THR CG2 HG22 sing N N 319 
THR CG2 HG23 sing N N 320 
THR OXT HXT  sing N N 321 
TRP N   CA   sing N N 322 
TRP N   H    sing N N 323 
TRP N   H2   sing N N 324 
TRP CA  C    sing N N 325 
TRP CA  CB   sing N N 326 
TRP CA  HA   sing N N 327 
TRP C   O    doub N N 328 
TRP C   OXT  sing N N 329 
TRP CB  CG   sing N N 330 
TRP CB  HB2  sing N N 331 
TRP CB  HB3  sing N N 332 
TRP CG  CD1  doub Y N 333 
TRP CG  CD2  sing Y N 334 
TRP CD1 NE1  sing Y N 335 
TRP CD1 HD1  sing N N 336 
TRP CD2 CE2  doub Y N 337 
TRP CD2 CE3  sing Y N 338 
TRP NE1 CE2  sing Y N 339 
TRP NE1 HE1  sing N N 340 
TRP CE2 CZ2  sing Y N 341 
TRP CE3 CZ3  doub Y N 342 
TRP CE3 HE3  sing N N 343 
TRP CZ2 CH2  doub Y N 344 
TRP CZ2 HZ2  sing N N 345 
TRP CZ3 CH2  sing Y N 346 
TRP CZ3 HZ3  sing N N 347 
TRP CH2 HH2  sing N N 348 
TRP OXT HXT  sing N N 349 
TYR N   CA   sing N N 350 
TYR N   H    sing N N 351 
TYR N   H2   sing N N 352 
TYR CA  C    sing N N 353 
TYR CA  CB   sing N N 354 
TYR CA  HA   sing N N 355 
TYR C   O    doub N N 356 
TYR C   OXT  sing N N 357 
TYR CB  CG   sing N N 358 
TYR CB  HB2  sing N N 359 
TYR CB  HB3  sing N N 360 
TYR CG  CD1  doub Y N 361 
TYR CG  CD2  sing Y N 362 
TYR CD1 CE1  sing Y N 363 
TYR CD1 HD1  sing N N 364 
TYR CD2 CE2  doub Y N 365 
TYR CD2 HD2  sing N N 366 
TYR CE1 CZ   doub Y N 367 
TYR CE1 HE1  sing N N 368 
TYR CE2 CZ   sing Y N 369 
TYR CE2 HE2  sing N N 370 
TYR CZ  OH   sing N N 371 
TYR OH  HH   sing N N 372 
TYR OXT HXT  sing N N 373 
VAL N   CA   sing N N 374 
VAL N   H    sing N N 375 
VAL N   H2   sing N N 376 
VAL CA  C    sing N N 377 
VAL CA  CB   sing N N 378 
VAL CA  HA   sing N N 379 
VAL C   O    doub N N 380 
VAL C   OXT  sing N N 381 
VAL CB  CG1  sing N N 382 
VAL CB  CG2  sing N N 383 
VAL CB  HB   sing N N 384 
VAL CG1 HG11 sing N N 385 
VAL CG1 HG12 sing N N 386 
VAL CG1 HG13 sing N N 387 
VAL CG2 HG21 sing N N 388 
VAL CG2 HG22 sing N N 389 
VAL CG2 HG23 sing N N 390 
VAL OXT HXT  sing N N 391 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2023-08-26 
_em_admin.deposition_site    PDBJ 
_em_admin.entry_id           8W5E 
_em_admin.last_update        2025-02-26 
_em_admin.map_release_date   2025-02-26 
_em_admin.title              'Cryo-EM structure of Qb-Ab4' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          10088 
_em_entity_assembly_naturalsource.organism             Mus 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         60 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K2 SUMMIT (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ?      ?          
'MODEL REFINEMENT'         ? 2  ? ? ? PHENIX 1.13_2998: 
'IMAGE ACQUISITION'        ? 3  ? ? 1 ?      ?          
MASKING                    ? 4  ? ? ? ?      ?          
'CTF CORRECTION'           ? 5  1 ? ? ?      ?          
'LAYERLINE INDEXING'       ? 6  ? ? ? ?      ?          
'DIFFRACTION INDEXING'     ? 7  ? ? ? ?      ?          
'MODEL FITTING'            ? 8  ? ? ? ?      ?          
OTHER                      ? 9  ? ? ? ?      ?          
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ?      ?          
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ?      ?          
CLASSIFICATION             ? 12 1 ? ? ?      ?          
RECONSTRUCTION             ? 13 1 ? ? ?      ?          
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Natural Science Foundation of China (NSFC)' China 81991495    1 
'National Natural Science Foundation of China (NSFC)' China 32241029    2 
'Chinese Academy of Sciences'                         China XDB29050600 3 
'Chinese Academy of Sciences'                         China XDB37010100 4 
# 
_atom_sites.entry_id                    8W5E 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
P 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . VAL A 1 5   ? 126.221 112.451 143.269 1.00 122.15 ? 5   VAL H N   1 
ATOM   2    C CA  . VAL A 1 5   ? 127.514 112.885 142.765 1.00 122.15 ? 5   VAL H CA  1 
ATOM   3    C C   . VAL A 1 5   ? 127.920 114.187 143.427 1.00 122.15 ? 5   VAL H C   1 
ATOM   4    O O   . VAL A 1 5   ? 127.270 115.214 143.249 1.00 122.15 ? 5   VAL H O   1 
ATOM   5    C CB  . VAL A 1 5   ? 127.490 113.040 141.251 1.00 122.15 ? 5   VAL H CB  1 
ATOM   6    C CG1 . VAL A 1 5   ? 128.833 113.555 140.757 1.00 122.15 ? 5   VAL H CG1 1 
ATOM   7    C CG2 . VAL A 1 5   ? 127.141 111.717 140.601 1.00 122.15 ? 5   VAL H CG2 1 
ATOM   8    N N   . GLN A 1 6   ? 129.002 114.135 144.187 1.00 125.20 ? 6   GLN H N   1 
ATOM   9    C CA  . GLN A 1 6   ? 129.459 115.249 144.995 1.00 125.20 ? 6   GLN H CA  1 
ATOM   10   C C   . GLN A 1 6   ? 130.655 115.932 144.337 1.00 125.20 ? 6   GLN H C   1 
ATOM   11   O O   . GLN A 1 6   ? 131.010 115.646 143.193 1.00 125.20 ? 6   GLN H O   1 
ATOM   12   C CB  . GLN A 1 6   ? 129.766 114.745 146.407 1.00 125.20 ? 6   GLN H CB  1 
ATOM   13   C CG  . GLN A 1 6   ? 130.808 113.633 146.490 1.00 125.20 ? 6   GLN H CG  1 
ATOM   14   C CD  . GLN A 1 6   ? 132.220 114.159 146.627 1.00 125.20 ? 6   GLN H CD  1 
ATOM   15   O OE1 . GLN A 1 6   ? 132.437 115.241 147.169 1.00 125.20 ? 6   GLN H OE1 1 
ATOM   16   N NE2 . GLN A 1 6   ? 133.188 113.393 146.149 1.00 125.20 ? 6   GLN H NE2 1 
ATOM   17   N N   . LEU A 1 7   ? 131.282 116.839 145.085 1.00 123.13 ? 7   LEU H N   1 
ATOM   18   C CA  . LEU A 1 7   ? 132.515 117.534 144.707 1.00 123.13 ? 7   LEU H CA  1 
ATOM   19   C C   . LEU A 1 7   ? 133.100 118.178 145.973 1.00 123.13 ? 7   LEU H C   1 
ATOM   20   O O   . LEU A 1 7   ? 132.383 118.838 146.697 1.00 123.13 ? 7   LEU H O   1 
ATOM   21   C CB  . LEU A 1 7   ? 132.273 118.570 143.648 1.00 123.13 ? 7   LEU H CB  1 
ATOM   22   C CG  . LEU A 1 7   ? 131.826 119.865 144.251 1.00 123.13 ? 7   LEU H CG  1 
ATOM   23   C CD1 . LEU A 1 7   ? 131.683 120.832 143.104 1.00 123.13 ? 7   LEU H CD1 1 
ATOM   24   C CD2 . LEU A 1 7   ? 130.499 119.613 144.922 1.00 123.13 ? 7   LEU H CD2 1 
ATOM   25   N N   . VAL A 1 8   ? 134.403 118.025 146.212 1.00 124.25 ? 8   VAL H N   1 
ATOM   26   C CA  . VAL A 1 8   ? 135.033 118.475 147.455 1.00 124.25 ? 8   VAL H CA  1 
ATOM   27   C C   . VAL A 1 8   ? 136.183 119.491 147.466 1.00 124.25 ? 8   VAL H C   1 
ATOM   28   O O   . VAL A 1 8   ? 137.198 119.269 146.841 1.00 124.25 ? 8   VAL H O   1 
ATOM   29   C CB  . VAL A 1 8   ? 135.645 117.227 148.052 1.00 124.25 ? 8   VAL H CB  1 
ATOM   30   C CG1 . VAL A 1 8   ? 136.561 116.620 147.023 1.00 124.25 ? 8   VAL H CG1 1 
ATOM   31   C CG2 . VAL A 1 8   ? 136.416 117.524 149.310 1.00 124.25 ? 8   VAL H CG2 1 
ATOM   32   N N   . GLU A 1 9   ? 136.042 120.556 148.263 1.00 130.74 ? 9   GLU H N   1 
ATOM   33   C CA  . GLU A 1 9   ? 137.024 121.632 148.441 1.00 130.74 ? 9   GLU H CA  1 
ATOM   34   C C   . GLU A 1 9   ? 138.241 121.194 149.224 1.00 130.74 ? 9   GLU H C   1 
ATOM   35   O O   . GLU A 1 9   ? 138.215 120.173 149.879 1.00 130.74 ? 9   GLU H O   1 
ATOM   36   C CB  . GLU A 1 9   ? 136.389 122.778 149.272 1.00 30.00  ? 9   GLU H CB  1 
ATOM   37   C CG  . GLU A 1 9   ? 136.706 122.717 150.781 1.00 30.00  ? 9   GLU H CG  1 
ATOM   38   C CD  . GLU A 1 9   ? 136.071 123.797 151.665 1.00 30.00  ? 9   GLU H CD  1 
ATOM   39   O OE1 . GLU A 1 9   ? 136.797 124.690 152.166 1.00 30.00  ? 9   GLU H OE1 1 
ATOM   40   O OE2 . GLU A 1 9   ? 134.852 123.721 151.912 1.00 30.00  ? 9   GLU H OE2 1 
ATOM   41   N N   . SER A 1 10  ? 139.343 121.913 149.075 1.00 138.28 ? 10  SER H N   1 
ATOM   42   C CA  . SER A 1 10  ? 140.514 121.687 149.906 1.00 138.28 ? 10  SER H CA  1 
ATOM   43   C C   . SER A 1 10  ? 141.294 122.991 149.961 1.00 138.28 ? 10  SER H C   1 
ATOM   44   O O   . SER A 1 10  ? 141.362 123.679 148.966 1.00 138.28 ? 10  SER H O   1 
ATOM   45   C CB  . SER A 1 10  ? 141.376 120.590 149.354 1.00 138.28 ? 10  SER H CB  1 
ATOM   46   O OG  . SER A 1 10  ? 142.670 120.747 149.870 1.00 138.28 ? 10  SER H OG  1 
ATOM   47   N N   . GLY A 1 11  ? 141.937 123.317 151.074 1.00 142.90 ? 11  GLY H N   1 
ATOM   48   C CA  . GLY A 1 11  ? 142.668 124.579 151.153 1.00 142.90 ? 11  GLY H CA  1 
ATOM   49   C C   . GLY A 1 11  ? 143.201 124.872 152.539 1.00 142.90 ? 11  GLY H C   1 
ATOM   50   O O   . GLY A 1 11  ? 142.745 124.278 153.498 1.00 142.90 ? 11  GLY H O   1 
ATOM   51   N N   . GLY A 1 12  ? 144.073 125.868 152.692 1.00 146.01 ? 12  GLY H N   1 
ATOM   52   C CA  . GLY A 1 12  ? 144.711 126.129 153.965 1.00 146.01 ? 12  GLY H CA  1 
ATOM   53   C C   . GLY A 1 12  ? 143.805 126.826 154.963 1.00 146.01 ? 12  GLY H C   1 
ATOM   54   O O   . GLY A 1 12  ? 142.643 127.141 154.703 1.00 146.01 ? 12  GLY H O   1 
ATOM   55   N N   . GLY A 1 13  ? 144.366 127.069 156.147 1.00 157.15 ? 13  GLY H N   1 
ATOM   56   C CA  . GLY A 1 13  ? 143.595 127.673 157.216 1.00 157.15 ? 13  GLY H CA  1 
ATOM   57   C C   . GLY A 1 13  ? 144.311 128.685 158.090 1.00 157.15 ? 13  GLY H C   1 
ATOM   58   O O   . GLY A 1 13  ? 143.711 129.215 159.028 1.00 157.15 ? 13  GLY H O   1 
ATOM   59   N N   . LEU A 1 14  ? 145.578 128.972 157.813 1.00 162.54 ? 14  LEU H N   1 
ATOM   60   C CA  . LEU A 1 14  ? 146.344 129.898 158.644 1.00 162.54 ? 14  LEU H CA  1 
ATOM   61   C C   . LEU A 1 14  ? 147.124 130.877 157.773 1.00 162.54 ? 14  LEU H C   1 
ATOM   62   O O   . LEU A 1 14  ? 148.311 131.128 157.976 1.00 162.54 ? 14  LEU H O   1 
ATOM   63   C CB  . LEU A 1 14  ? 147.223 129.126 159.633 1.00 162.54 ? 14  LEU H CB  1 
ATOM   64   C CG  . LEU A 1 14  ? 148.166 127.968 159.267 1.00 162.54 ? 14  LEU H CG  1 
ATOM   65   C CD1 . LEU A 1 14  ? 149.602 128.371 158.939 1.00 162.54 ? 14  LEU H CD1 1 
ATOM   66   C CD2 . LEU A 1 14  ? 148.156 126.943 160.397 1.00 162.54 ? 14  LEU H CD2 1 
ATOM   67   N N   . VAL A 1 15  ? 146.437 131.476 156.800 1.00 167.78 ? 15  VAL H N   1 
ATOM   68   C CA  . VAL A 1 15  ? 147.087 132.415 155.895 1.00 167.78 ? 15  VAL H CA  1 
ATOM   69   C C   . VAL A 1 15  ? 147.403 133.719 156.624 1.00 167.78 ? 15  VAL H C   1 
ATOM   70   O O   . VAL A 1 15  ? 146.620 134.210 157.451 1.00 167.78 ? 15  VAL H O   1 
ATOM   71   C CB  . VAL A 1 15  ? 146.215 132.630 154.642 1.00 167.78 ? 15  VAL H CB  1 
ATOM   72   C CG1 . VAL A 1 15  ? 144.836 133.192 154.989 1.00 167.78 ? 15  VAL H CG1 1 
ATOM   73   C CG2 . VAL A 1 15  ? 146.924 133.503 153.606 1.00 167.78 ? 15  VAL H CG2 1 
ATOM   74   N N   . GLN A 1 16  ? 148.597 134.237 156.381 1.00 173.21 ? 16  GLN H N   1 
ATOM   75   C CA  . GLN A 1 16  ? 149.033 135.519 156.904 1.00 173.21 ? 16  GLN H CA  1 
ATOM   76   C C   . GLN A 1 16  ? 148.389 136.645 156.100 1.00 173.21 ? 16  GLN H C   1 
ATOM   77   O O   . GLN A 1 16  ? 148.265 136.533 154.878 1.00 173.21 ? 16  GLN H O   1 
ATOM   78   C CB  . GLN A 1 16  ? 150.553 135.623 156.826 1.00 173.21 ? 16  GLN H CB  1 
ATOM   79   C CG  . GLN A 1 16  ? 151.154 136.859 157.462 1.00 173.21 ? 16  GLN H CG  1 
ATOM   80   C CD  . GLN A 1 16  ? 151.008 136.861 158.968 1.00 173.21 ? 16  GLN H CD  1 
ATOM   81   O OE1 . GLN A 1 16  ? 151.134 135.822 159.614 1.00 173.21 ? 16  GLN H OE1 1 
ATOM   82   N NE2 . GLN A 1 16  ? 150.765 138.034 159.539 1.00 173.21 ? 16  GLN H NE2 1 
ATOM   83   N N   . PRO A 1 17  ? 147.937 137.722 156.762 1.00 173.98 ? 17  PRO H N   1 
ATOM   84   C CA  . PRO A 1 17  ? 147.387 138.871 156.028 1.00 173.98 ? 17  PRO H CA  1 
ATOM   85   C C   . PRO A 1 17  ? 148.400 139.539 155.113 1.00 173.98 ? 17  PRO H C   1 
ATOM   86   O O   . PRO A 1 17  ? 149.391 140.117 155.565 1.00 173.98 ? 17  PRO H O   1 
ATOM   87   C CB  . PRO A 1 17  ? 146.937 139.814 157.149 1.00 173.98 ? 17  PRO H CB  1 
ATOM   88   C CG  . PRO A 1 17  ? 146.645 138.909 158.289 1.00 173.98 ? 17  PRO H CG  1 
ATOM   89   C CD  . PRO A 1 17  ? 147.664 137.813 158.206 1.00 173.98 ? 17  PRO H CD  1 
ATOM   90   N N   . GLY A 1 18  ? 148.146 139.443 153.811 1.00 171.35 ? 18  GLY H N   1 
ATOM   91   C CA  . GLY A 1 18  ? 149.077 139.898 152.803 1.00 171.35 ? 18  GLY H CA  1 
ATOM   92   C C   . GLY A 1 18  ? 149.364 138.816 151.785 1.00 171.35 ? 18  GLY H C   1 
ATOM   93   O O   . GLY A 1 18  ? 149.552 139.099 150.599 1.00 171.35 ? 18  GLY H O   1 
ATOM   94   N N   . GLY A 1 19  ? 149.383 137.565 152.239 1.00 165.86 ? 19  GLY H N   1 
ATOM   95   C CA  . GLY A 1 19  ? 149.700 136.437 151.389 1.00 165.86 ? 19  GLY H CA  1 
ATOM   96   C C   . GLY A 1 19  ? 148.534 136.003 150.525 1.00 165.86 ? 19  GLY H C   1 
ATOM   97   O O   . GLY A 1 19  ? 147.565 136.737 150.313 1.00 165.86 ? 19  GLY H O   1 
ATOM   98   N N   . SER A 1 20  ? 148.638 134.778 150.015 1.00 156.96 ? 20  SER H N   1 
ATOM   99   C CA  . SER A 1 20  ? 147.608 134.222 149.150 1.00 156.96 ? 20  SER H CA  1 
ATOM   100  C C   . SER A 1 20  ? 147.626 132.706 149.264 1.00 156.96 ? 20  SER H C   1 
ATOM   101  O O   . SER A 1 20  ? 148.624 132.106 149.667 1.00 156.96 ? 20  SER H O   1 
ATOM   102  C CB  . SER A 1 20  ? 147.808 134.648 147.693 1.00 156.96 ? 20  SER H CB  1 
ATOM   103  O OG  . SER A 1 20  ? 148.997 134.089 147.168 1.00 156.96 ? 20  SER H OG  1 
ATOM   104  N N   . LEU A 1 21  ? 146.506 132.091 148.898 1.00 151.46 ? 21  LEU H N   1 
ATOM   105  C CA  . LEU A 1 21  ? 146.357 130.644 148.928 1.00 151.46 ? 21  LEU H CA  1 
ATOM   106  C C   . LEU A 1 21  ? 145.885 130.157 147.566 1.00 151.46 ? 21  LEU H C   1 
ATOM   107  O O   . LEU A 1 21  ? 145.627 130.946 146.654 1.00 151.46 ? 21  LEU H O   1 
ATOM   108  C CB  . LEU A 1 21  ? 145.371 130.204 150.014 1.00 151.46 ? 21  LEU H CB  1 
ATOM   109  C CG  . LEU A 1 21  ? 145.775 130.465 151.457 1.00 151.46 ? 21  LEU H CG  1 
ATOM   110  C CD1 . LEU A 1 21  ? 144.654 130.036 152.385 1.00 151.46 ? 21  LEU H CD1 1 
ATOM   111  C CD2 . LEU A 1 21  ? 147.061 129.734 151.776 1.00 151.46 ? 21  LEU H CD2 1 
ATOM   112  N N   . LYS A 1 22  ? 145.769 128.836 147.436 1.00 147.00 ? 22  LYS H N   1 
ATOM   113  C CA  . LYS A 1 22  ? 145.246 128.203 146.225 1.00 147.00 ? 22  LYS H CA  1 
ATOM   114  C C   . LYS A 1 22  ? 144.273 127.113 146.658 1.00 147.00 ? 22  LYS H C   1 
ATOM   115  O O   . LYS A 1 22  ? 144.692 126.014 147.029 1.00 147.00 ? 22  LYS H O   1 
ATOM   116  C CB  . LYS A 1 22  ? 146.360 127.626 145.360 1.00 147.00 ? 22  LYS H CB  1 
ATOM   117  C CG  . LYS A 1 22  ? 147.232 128.659 144.679 1.00 147.00 ? 22  LYS H CG  1 
ATOM   118  C CD  . LYS A 1 22  ? 148.378 128.003 143.936 1.00 147.00 ? 22  LYS H CD  1 
ATOM   119  C CE  . LYS A 1 22  ? 147.879 127.260 142.713 1.00 147.00 ? 22  LYS H CE  1 
ATOM   120  N NZ  . LYS A 1 22  ? 149.008 126.714 141.918 1.00 147.00 ? 22  LYS H NZ  1 
ATOM   121  N N   . LEU A 1 23  ? 142.983 127.421 146.619 1.00 141.35 ? 23  LEU H N   1 
ATOM   122  C CA  . LEU A 1 23  ? 141.970 126.406 146.853 1.00 141.35 ? 23  LEU H CA  1 
ATOM   123  C C   . LEU A 1 23  ? 141.908 125.448 145.673 1.00 141.35 ? 23  LEU H C   1 
ATOM   124  O O   . LEU A 1 23  ? 141.908 125.865 144.511 1.00 141.35 ? 23  LEU H O   1 
ATOM   125  C CB  . LEU A 1 23  ? 140.606 127.053 147.056 1.00 141.35 ? 23  LEU H CB  1 
ATOM   126  C CG  . LEU A 1 23  ? 140.441 127.982 148.251 1.00 141.35 ? 23  LEU H CG  1 
ATOM   127  C CD1 . LEU A 1 23  ? 139.068 128.595 148.206 1.00 141.35 ? 23  LEU H CD1 1 
ATOM   128  C CD2 . LEU A 1 23  ? 140.629 127.227 149.533 1.00 141.35 ? 23  LEU H CD2 1 
ATOM   129  N N   . SER A 1 24  ? 141.858 124.158 145.975 1.00 138.39 ? 24  SER H N   1 
ATOM   130  C CA  . SER A 1 24  ? 141.661 123.132 144.967 1.00 138.39 ? 24  SER H CA  1 
ATOM   131  C C   . SER A 1 24  ? 140.268 122.546 145.127 1.00 138.39 ? 24  SER H C   1 
ATOM   132  O O   . SER A 1 24  ? 139.700 122.558 146.222 1.00 138.39 ? 24  SER H O   1 
ATOM   133  C CB  . SER A 1 24  ? 142.713 122.027 145.086 1.00 138.39 ? 24  SER H CB  1 
ATOM   134  O OG  . SER A 1 24  ? 144.012 122.535 144.847 1.00 138.39 ? 24  SER H OG  1 
ATOM   135  N N   . CYS A 1 25  ? 139.710 122.041 144.031 1.00 136.28 ? 25  CYS H N   1 
ATOM   136  C CA  . CYS A 1 25  ? 138.375 121.454 144.104 1.00 136.28 ? 25  CYS H CA  1 
ATOM   137  C C   . CYS A 1 25  ? 138.265 120.347 143.067 1.00 136.28 ? 25  CYS H C   1 
ATOM   138  O O   . CYS A 1 25  ? 138.315 120.614 141.865 1.00 136.28 ? 25  CYS H O   1 
ATOM   139  C CB  . CYS A 1 25  ? 137.312 122.523 143.897 1.00 136.28 ? 25  CYS H CB  1 
ATOM   140  S SG  . CYS A 1 25  ? 135.606 122.002 144.118 1.00 136.28 ? 25  CYS H SG  1 
ATOM   141  N N   . ALA A 1 26  ? 138.095 119.118 143.537 1.00 126.52 ? 26  ALA H N   1 
ATOM   142  C CA  . ALA A 1 26  ? 138.037 117.938 142.690 1.00 126.52 ? 26  ALA H CA  1 
ATOM   143  C C   . ALA A 1 26  ? 136.600 117.488 142.467 1.00 126.52 ? 26  ALA H C   1 
ATOM   144  O O   . ALA A 1 26  ? 135.739 117.620 143.343 1.00 126.52 ? 26  ALA H O   1 
ATOM   145  C CB  . ALA A 1 26  ? 138.842 116.793 143.305 1.00 126.52 ? 26  ALA H CB  1 
ATOM   146  N N   . ALA A 1 27  ? 136.362 116.936 141.280 1.00 121.54 ? 27  ALA H N   1 
ATOM   147  C CA  . ALA A 1 27  ? 135.069 116.429 140.858 1.00 121.54 ? 27  ALA H CA  1 
ATOM   148  C C   . ALA A 1 27  ? 134.926 114.957 141.228 1.00 121.54 ? 27  ALA H C   1 
ATOM   149  O O   . ALA A 1 27  ? 135.871 114.311 141.681 1.00 121.54 ? 27  ALA H O   1 
ATOM   150  C CB  . ALA A 1 27  ? 134.894 116.611 139.355 1.00 121.54 ? 27  ALA H CB  1 
ATOM   151  N N   . SER A 1 28  ? 133.715 114.421 141.029 1.00 122.11 ? 28  SER H N   1 
ATOM   152  C CA  . SER A 1 28  ? 133.460 113.043 141.429 1.00 122.11 ? 28  SER H CA  1 
ATOM   153  C C   . SER A 1 28  ? 132.564 112.272 140.465 1.00 122.11 ? 28  SER H C   1 
ATOM   154  O O   . SER A 1 28  ? 131.975 111.263 140.868 1.00 122.11 ? 28  SER H O   1 
ATOM   155  C CB  . SER A 1 28  ? 132.828 112.995 142.816 1.00 122.11 ? 28  SER H CB  1 
ATOM   156  O OG  . SER A 1 28  ? 133.683 113.571 143.786 1.00 122.11 ? 28  SER H OG  1 
ATOM   157  N N   . GLY A 1 29  ? 132.428 112.701 139.217 1.00 118.12 ? 29  GLY H N   1 
ATOM   158  C CA  . GLY A 1 29  ? 131.671 111.885 138.289 1.00 118.12 ? 29  GLY H CA  1 
ATOM   159  C C   . GLY A 1 29  ? 130.648 112.578 137.413 1.00 118.12 ? 29  GLY H C   1 
ATOM   160  O O   . GLY A 1 29  ? 129.846 111.908 136.759 1.00 118.12 ? 29  GLY H O   1 
ATOM   161  N N   . PHE A 1 30  ? 130.650 113.906 137.385 1.00 123.00 ? 30  PHE H N   1 
ATOM   162  C CA  . PHE A 1 30  ? 129.873 114.647 136.403 1.00 123.00 ? 30  PHE H CA  1 
ATOM   163  C C   . PHE A 1 30  ? 130.712 115.059 135.202 1.00 123.00 ? 30  PHE H C   1 
ATOM   164  O O   . PHE A 1 30  ? 130.293 115.935 134.438 1.00 123.00 ? 30  PHE H O   1 
ATOM   165  C CB  . PHE A 1 30  ? 129.209 115.869 137.051 1.00 123.00 ? 30  PHE H CB  1 
ATOM   166  C CG  . PHE A 1 30  ? 130.171 116.844 137.677 1.00 123.00 ? 30  PHE H CG  1 
ATOM   167  C CD1 . PHE A 1 30  ? 130.545 116.702 139.000 1.00 123.00 ? 30  PHE H CD1 1 
ATOM   168  C CD2 . PHE A 1 30  ? 130.663 117.923 136.962 1.00 123.00 ? 30  PHE H CD2 1 
ATOM   169  C CE1 . PHE A 1 30  ? 131.414 117.594 139.586 1.00 123.00 ? 30  PHE H CE1 1 
ATOM   170  C CE2 . PHE A 1 30  ? 131.528 118.819 137.542 1.00 123.00 ? 30  PHE H CE2 1 
ATOM   171  C CZ  . PHE A 1 30  ? 131.911 118.652 138.854 1.00 123.00 ? 30  PHE H CZ  1 
ATOM   172  N N   . THR A 1 31  ? 131.912 114.479 135.065 1.00 128.84 ? 31  THR H N   1 
ATOM   173  C CA  . THR A 1 31  ? 132.880 114.555 133.961 1.00 128.84 ? 31  THR H CA  1 
ATOM   174  C C   . THR A 1 31  ? 133.588 115.902 133.841 1.00 128.84 ? 31  THR H C   1 
ATOM   175  O O   . THR A 1 31  ? 134.492 116.040 133.010 1.00 128.84 ? 31  THR H O   1 
ATOM   176  C CB  . THR A 1 31  ? 132.251 114.208 132.598 1.00 128.84 ? 31  THR H CB  1 
ATOM   177  O OG1 . THR A 1 31  ? 131.284 115.200 132.228 1.00 128.84 ? 31  THR H OG1 1 
ATOM   178  C CG2 . THR A 1 31  ? 131.593 112.840 132.634 1.00 128.84 ? 31  THR H CG2 1 
ATOM   179  N N   . PHE A 1 32  ? 133.145 116.916 134.596 1.00 128.23 ? 32  PHE H N   1 
ATOM   180  C CA  . PHE A 1 32  ? 133.789 118.218 134.817 1.00 128.23 ? 32  PHE H CA  1 
ATOM   181  C C   . PHE A 1 32  ? 133.861 119.098 133.566 1.00 128.23 ? 32  PHE H C   1 
ATOM   182  O O   . PHE A 1 32  ? 134.105 120.304 133.659 1.00 128.23 ? 32  PHE H O   1 
ATOM   183  C CB  . PHE A 1 32  ? 135.182 118.013 135.426 1.00 128.23 ? 32  PHE H CB  1 
ATOM   184  C CG  . PHE A 1 32  ? 135.861 119.279 135.845 1.00 128.23 ? 32  PHE H CG  1 
ATOM   185  C CD1 . PHE A 1 32  ? 135.435 119.969 136.964 1.00 128.23 ? 32  PHE H CD1 1 
ATOM   186  C CD2 . PHE A 1 32  ? 136.915 119.787 135.110 1.00 128.23 ? 32  PHE H CD2 1 
ATOM   187  C CE1 . PHE A 1 32  ? 136.058 121.137 137.351 1.00 128.23 ? 32  PHE H CE1 1 
ATOM   188  C CE2 . PHE A 1 32  ? 137.546 120.953 135.495 1.00 128.23 ? 32  PHE H CE2 1 
ATOM   189  C CZ  . PHE A 1 32  ? 137.112 121.631 136.616 1.00 128.23 ? 32  PHE H CZ  1 
ATOM   190  N N   . SER A 1 33  ? 133.552 118.546 132.404 1.00 120.32 ? 33  SER H N   1 
ATOM   191  C CA  . SER A 1 33  ? 133.157 119.347 131.271 1.00 120.32 ? 33  SER H CA  1 
ATOM   192  C C   . SER A 1 33  ? 131.652 119.534 131.365 1.00 120.32 ? 33  SER H C   1 
ATOM   193  O O   . SER A 1 33  ? 131.039 119.247 132.399 1.00 120.32 ? 33  SER H O   1 
ATOM   194  C CB  . SER A 1 33  ? 133.582 118.683 129.966 1.00 120.32 ? 33  SER H CB  1 
ATOM   195  O OG  . SER A 1 33  ? 132.912 117.448 129.797 1.00 120.32 ? 33  SER H OG  1 
ATOM   196  N N   . ASP A 1 34  ? 131.067 120.128 130.318 1.00 120.24 ? 34  ASP H N   1 
ATOM   197  C CA  . ASP A 1 34  ? 129.625 120.199 130.064 1.00 120.24 ? 34  ASP H CA  1 
ATOM   198  C C   . ASP A 1 34  ? 128.906 121.133 131.048 1.00 120.24 ? 34  ASP H C   1 
ATOM   199  O O   . ASP A 1 34  ? 127.742 121.482 130.838 1.00 120.24 ? 34  ASP H O   1 
ATOM   200  C CB  . ASP A 1 34  ? 129.031 118.777 130.073 1.00 120.24 ? 34  ASP H CB  1 
ATOM   201  C CG  . ASP A 1 34  ? 127.719 118.664 129.333 1.00 120.24 ? 34  ASP H CG  1 
ATOM   202  O OD1 . ASP A 1 34  ? 127.229 119.670 128.800 1.00 120.24 ? 34  ASP H OD1 1 
ATOM   203  O OD2 . ASP A 1 34  ? 127.178 117.541 129.256 1.00 120.24 ? 34  ASP H OD2 1 
ATOM   204  N N   . TYR A 1 35  ? 129.611 121.638 132.056 1.00 120.87 ? 35  TYR H N   1 
ATOM   205  C CA  . TYR A 1 35  ? 129.018 122.160 133.276 1.00 120.87 ? 35  TYR H CA  1 
ATOM   206  C C   . TYR A 1 35  ? 129.833 123.344 133.764 1.00 120.87 ? 35  TYR H C   1 
ATOM   207  O O   . TYR A 1 35  ? 131.045 123.228 133.953 1.00 120.87 ? 35  TYR H O   1 
ATOM   208  C CB  . TYR A 1 35  ? 129.004 121.077 134.355 1.00 120.87 ? 35  TYR H CB  1 
ATOM   209  C CG  . TYR A 1 35  ? 128.046 119.952 134.117 1.00 120.87 ? 35  TYR H CG  1 
ATOM   210  C CD1 . TYR A 1 35  ? 126.812 120.185 133.527 1.00 120.87 ? 35  TYR H CD1 1 
ATOM   211  C CD2 . TYR A 1 35  ? 128.386 118.641 134.431 1.00 120.87 ? 35  TYR H CD2 1 
ATOM   212  C CE1 . TYR A 1 35  ? 125.932 119.148 133.287 1.00 120.87 ? 35  TYR H CE1 1 
ATOM   213  C CE2 . TYR A 1 35  ? 127.509 117.608 134.198 1.00 120.87 ? 35  TYR H CE2 1 
ATOM   214  C CZ  . TYR A 1 35  ? 126.288 117.867 133.618 1.00 120.87 ? 35  TYR H CZ  1 
ATOM   215  O OH  . TYR A 1 35  ? 125.399 116.849 133.380 1.00 120.87 ? 35  TYR H OH  1 
ATOM   216  N N   . GLY A 1 36  ? 129.173 124.473 133.973 1.00 120.98 ? 36  GLY H N   1 
ATOM   217  C CA  . GLY A 1 36  ? 129.823 125.598 134.613 1.00 120.98 ? 36  GLY H CA  1 
ATOM   218  C C   . GLY A 1 36  ? 129.827 125.441 136.118 1.00 120.98 ? 36  GLY H C   1 
ATOM   219  O O   . GLY A 1 36  ? 129.141 124.581 136.664 1.00 120.98 ? 36  GLY H O   1 
ATOM   220  N N   . MET A 1 37  ? 130.605 126.287 136.788 1.00 124.02 ? 37  MET H N   1 
ATOM   221  C CA  . MET A 1 37  ? 130.719 126.206 138.237 1.00 124.02 ? 37  MET H CA  1 
ATOM   222  C C   . MET A 1 37  ? 131.163 127.557 138.788 1.00 124.02 ? 37  MET H C   1 
ATOM   223  O O   . MET A 1 37  ? 131.353 128.525 138.043 1.00 124.02 ? 37  MET H O   1 
ATOM   224  C CB  . MET A 1 37  ? 131.653 125.063 138.634 1.00 124.02 ? 37  MET H CB  1 
ATOM   225  C CG  . MET A 1 37  ? 133.066 125.224 138.206 1.00 124.02 ? 37  MET H CG  1 
ATOM   226  S SD  . MET A 1 37  ? 133.968 123.732 138.589 1.00 124.02 ? 37  MET H SD  1 
ATOM   227  C CE  . MET A 1 37  ? 133.860 123.787 140.359 1.00 124.02 ? 37  MET H CE  1 
ATOM   228  N N   . ALA A 1 38  ? 131.297 127.624 140.112 1.00 127.67 ? 38  ALA H N   1 
ATOM   229  C CA  . ALA A 1 38  ? 131.467 128.897 140.795 1.00 127.67 ? 38  ALA H CA  1 
ATOM   230  C C   . ALA A 1 38  ? 132.001 128.665 142.199 1.00 127.67 ? 38  ALA H C   1 
ATOM   231  O O   . ALA A 1 38  ? 131.918 127.561 142.753 1.00 127.67 ? 38  ALA H O   1 
ATOM   232  C CB  . ALA A 1 38  ? 130.151 129.675 140.862 1.00 127.67 ? 38  ALA H CB  1 
ATOM   233  N N   . TRP A 1 39  ? 132.538 129.737 142.767 1.00 135.34 ? 39  TRP H N   1 
ATOM   234  C CA  . TRP A 1 39  ? 133.051 129.760 144.127 1.00 135.34 ? 39  TRP H CA  1 
ATOM   235  C C   . TRP A 1 39  ? 132.187 130.693 144.957 1.00 135.34 ? 39  TRP H C   1 
ATOM   236  O O   . TRP A 1 39  ? 131.988 131.852 144.580 1.00 135.34 ? 39  TRP H O   1 
ATOM   237  C CB  . TRP A 1 39  ? 134.497 130.243 144.158 1.00 135.34 ? 39  TRP H CB  1 
ATOM   238  C CG  . TRP A 1 39  ? 135.469 129.296 143.594 1.00 135.34 ? 39  TRP H CG  1 
ATOM   239  C CD1 . TRP A 1 39  ? 135.945 129.273 142.321 1.00 135.34 ? 39  TRP H CD1 1 
ATOM   240  C CD2 . TRP A 1 39  ? 136.127 128.245 144.292 1.00 135.34 ? 39  TRP H CD2 1 
ATOM   241  N NE1 . TRP A 1 39  ? 136.851 128.254 142.175 1.00 135.34 ? 39  TRP H NE1 1 
ATOM   242  C CE2 . TRP A 1 39  ? 136.980 127.608 143.376 1.00 135.34 ? 39  TRP H CE2 1 
ATOM   243  C CE3 . TRP A 1 39  ? 136.070 127.772 145.602 1.00 135.34 ? 39  TRP H CE3 1 
ATOM   244  C CZ2 . TRP A 1 39  ? 137.770 126.524 143.727 1.00 135.34 ? 39  TRP H CZ2 1 
ATOM   245  C CZ3 . TRP A 1 39  ? 136.854 126.700 145.950 1.00 135.34 ? 39  TRP H CZ3 1 
ATOM   246  C CH2 . TRP A 1 39  ? 137.695 126.086 145.018 1.00 135.34 ? 39  TRP H CH2 1 
ATOM   247  N N   . VAL A 1 40  ? 131.675 130.193 146.075 1.00 132.10 ? 40  VAL H N   1 
ATOM   248  C CA  . VAL A 1 40  ? 131.091 131.069 147.079 1.00 132.10 ? 40  VAL H CA  1 
ATOM   249  C C   . VAL A 1 40  ? 131.336 130.474 148.459 1.00 132.10 ? 40  VAL H C   1 
ATOM   250  O O   . VAL A 1 40  ? 130.950 129.337 148.749 1.00 132.10 ? 40  VAL H O   1 
ATOM   251  C CB  . VAL A 1 40  ? 129.598 131.358 146.801 1.00 132.10 ? 40  VAL H CB  1 
ATOM   252  C CG1 . VAL A 1 40  ? 128.766 130.093 146.578 1.00 132.10 ? 40  VAL H CG1 1 
ATOM   253  C CG2 . VAL A 1 40  ? 129.016 132.188 147.931 1.00 132.10 ? 40  VAL H CG2 1 
ATOM   254  N N   . ARG A 1 41  ? 132.045 131.212 149.298 1.00 139.20 ? 41  ARG H N   1 
ATOM   255  C CA  . ARG A 1 41  ? 132.214 130.834 150.687 1.00 139.20 ? 41  ARG H CA  1 
ATOM   256  C C   . ARG A 1 41  ? 131.258 131.667 151.525 1.00 139.20 ? 41  ARG H C   1 
ATOM   257  O O   . ARG A 1 41  ? 130.453 132.437 151.003 1.00 139.20 ? 41  ARG H O   1 
ATOM   258  C CB  . ARG A 1 41  ? 133.666 131.015 151.129 1.00 139.20 ? 41  ARG H CB  1 
ATOM   259  C CG  . ARG A 1 41  ? 134.098 132.460 151.199 1.00 139.20 ? 41  ARG H CG  1 
ATOM   260  C CD  . ARG A 1 41  ? 135.562 132.583 151.527 1.00 139.20 ? 41  ARG H CD  1 
ATOM   261  N NE  . ARG A 1 41  ? 136.394 132.155 150.415 1.00 139.20 ? 41  ARG H NE  1 
ATOM   262  C CZ  . ARG A 1 41  ? 137.710 132.034 150.485 1.00 139.20 ? 41  ARG H CZ  1 
ATOM   263  N NH1 . ARG A 1 41  ? 138.397 131.647 149.425 1.00 139.20 ? 41  ARG H NH1 1 
ATOM   264  N NH2 . ARG A 1 41  ? 138.340 132.304 151.618 1.00 139.20 ? 41  ARG H NH2 1 
ATOM   265  N N   . GLN A 1 42  ? 131.328 131.502 152.838 1.00 143.99 ? 42  GLN H N   1 
ATOM   266  C CA  . GLN A 1 42  ? 130.462 132.255 153.724 1.00 143.99 ? 42  GLN H CA  1 
ATOM   267  C C   . GLN A 1 42  ? 131.246 132.781 154.913 1.00 143.99 ? 42  GLN H C   1 
ATOM   268  O O   . GLN A 1 42  ? 132.220 132.173 155.367 1.00 143.99 ? 42  GLN H O   1 
ATOM   269  C CB  . GLN A 1 42  ? 129.269 131.418 154.206 1.00 143.99 ? 42  GLN H CB  1 
ATOM   270  C CG  . GLN A 1 42  ? 129.607 130.211 155.048 1.00 143.99 ? 42  GLN H CG  1 
ATOM   271  C CD  . GLN A 1 42  ? 128.372 129.422 155.431 1.00 143.99 ? 42  GLN H CD  1 
ATOM   272  O OE1 . GLN A 1 42  ? 127.250 129.815 155.110 1.00 143.99 ? 42  GLN H OE1 1 
ATOM   273  N NE2 . GLN A 1 42  ? 128.570 128.304 156.119 1.00 143.99 ? 42  GLN H NE2 1 
ATOM   274  N N   . ALA A 1 43  ? 130.819 133.944 155.383 1.00 145.00 ? 43  ALA H N   1 
ATOM   275  C CA  . ALA A 1 43  ? 131.225 134.441 156.676 1.00 145.00 ? 43  ALA H CA  1 
ATOM   276  C C   . ALA A 1 43  ? 130.528 133.619 157.760 1.00 145.00 ? 43  ALA H C   1 
ATOM   277  O O   . ALA A 1 43  ? 129.535 132.941 157.488 1.00 145.00 ? 43  ALA H O   1 
ATOM   278  C CB  . ALA A 1 43  ? 130.862 135.922 156.786 1.00 145.00 ? 43  ALA H CB  1 
ATOM   279  N N   . PRO A 1 44  ? 131.010 133.668 159.014 1.00 142.29 ? 44  PRO H N   1 
ATOM   280  C CA  . PRO A 1 44  ? 130.255 133.013 160.096 1.00 142.29 ? 44  PRO H CA  1 
ATOM   281  C C   . PRO A 1 44  ? 129.009 133.768 160.549 1.00 142.29 ? 44  PRO H C   1 
ATOM   282  O O   . PRO A 1 44  ? 128.391 133.394 161.550 1.00 142.29 ? 44  PRO H O   1 
ATOM   283  C CB  . PRO A 1 44  ? 131.283 132.918 161.228 1.00 142.29 ? 44  PRO H CB  1 
ATOM   284  C CG  . PRO A 1 44  ? 132.257 133.991 160.945 1.00 142.29 ? 44  PRO H CG  1 
ATOM   285  C CD  . PRO A 1 44  ? 132.361 134.055 159.460 1.00 142.29 ? 44  PRO H CD  1 
ATOM   286  N N   . ARG A 1 45  ? 128.629 134.826 159.830 1.00 146.32 ? 45  ARG H N   1 
ATOM   287  C CA  . ARG A 1 45  ? 127.427 135.588 160.116 1.00 146.32 ? 45  ARG H CA  1 
ATOM   288  C C   . ARG A 1 45  ? 126.386 135.543 159.009 1.00 146.32 ? 45  ARG H C   1 
ATOM   289  O O   . ARG A 1 45  ? 125.216 135.827 159.284 1.00 146.32 ? 45  ARG H O   1 
ATOM   290  C CB  . ARG A 1 45  ? 127.782 137.058 160.381 1.00 146.32 ? 45  ARG H CB  1 
ATOM   291  C CG  . ARG A 1 45  ? 128.363 137.768 159.167 1.00 146.32 ? 45  ARG H CG  1 
ATOM   292  C CD  . ARG A 1 45  ? 128.672 139.220 159.457 1.00 146.32 ? 45  ARG H CD  1 
ATOM   293  N NE  . ARG A 1 45  ? 129.735 139.365 160.445 1.00 146.32 ? 45  ARG H NE  1 
ATOM   294  C CZ  . ARG A 1 45  ? 131.028 139.413 160.144 1.00 146.32 ? 45  ARG H CZ  1 
ATOM   295  N NH1 . ARG A 1 45  ? 131.419 139.329 158.880 1.00 146.32 ? 45  ARG H NH1 1 
ATOM   296  N NH2 . ARG A 1 45  ? 131.931 139.549 161.105 1.00 146.32 ? 45  ARG H NH2 1 
ATOM   297  N N   . LYS A 1 46  ? 126.765 135.194 157.778 1.00 143.27 ? 46  LYS H N   1 
ATOM   298  C CA  . LYS A 1 46  ? 125.861 135.306 156.640 1.00 143.27 ? 46  LYS H CA  1 
ATOM   299  C C   . LYS A 1 46  ? 126.332 134.372 155.536 1.00 143.27 ? 46  LYS H C   1 
ATOM   300  O O   . LYS A 1 46  ? 127.521 134.351 155.207 1.00 143.27 ? 46  LYS H O   1 
ATOM   301  C CB  . LYS A 1 46  ? 125.805 136.752 156.142 1.00 143.27 ? 46  LYS H CB  1 
ATOM   302  C CG  . LYS A 1 46  ? 124.852 136.997 154.991 1.00 143.27 ? 46  LYS H CG  1 
ATOM   303  C CD  . LYS A 1 46  ? 124.776 138.483 154.679 1.00 143.27 ? 46  LYS H CD  1 
ATOM   304  C CE  . LYS A 1 46  ? 126.071 138.972 154.046 1.00 143.27 ? 46  LYS H CE  1 
ATOM   305  N NZ  . LYS A 1 46  ? 126.002 140.397 153.627 1.00 143.27 ? 46  LYS H NZ  1 
ATOM   306  N N   . GLY A 1 47  ? 125.403 133.602 154.974 1.00 136.92 ? 47  GLY H N   1 
ATOM   307  C CA  . GLY A 1 47  ? 125.740 132.572 154.019 1.00 136.92 ? 47  GLY H CA  1 
ATOM   308  C C   . GLY A 1 47  ? 126.088 133.018 152.609 1.00 136.92 ? 47  GLY H C   1 
ATOM   309  O O   . GLY A 1 47  ? 127.249 132.956 152.196 1.00 136.92 ? 47  GLY H O   1 
ATOM   310  N N   . PRO A 1 48  ? 125.101 133.490 151.838 1.00 135.32 ? 48  PRO H N   1 
ATOM   311  C CA  . PRO A 1 48  ? 125.339 133.684 150.401 1.00 135.32 ? 48  PRO H CA  1 
ATOM   312  C C   . PRO A 1 48  ? 126.152 134.924 150.081 1.00 135.32 ? 48  PRO H C   1 
ATOM   313  O O   . PRO A 1 48  ? 125.668 136.057 150.134 1.00 135.32 ? 48  PRO H O   1 
ATOM   314  C CB  . PRO A 1 48  ? 123.924 133.773 149.820 1.00 135.32 ? 48  PRO H CB  1 
ATOM   315  C CG  . PRO A 1 48  ? 123.089 134.237 150.941 1.00 135.32 ? 48  PRO H CG  1 
ATOM   316  C CD  . PRO A 1 48  ? 123.680 133.644 152.178 1.00 135.32 ? 48  PRO H CD  1 
ATOM   317  N N   . GLU A 1 49  ? 127.408 134.693 149.751 1.00 139.65 ? 49  GLU H N   1 
ATOM   318  C CA  . GLU A 1 49  ? 128.333 135.743 149.363 1.00 139.65 ? 49  GLU H CA  1 
ATOM   319  C C   . GLU A 1 49  ? 128.373 135.872 147.842 1.00 139.65 ? 49  GLU H C   1 
ATOM   320  O O   . GLU A 1 49  ? 127.472 135.420 147.132 1.00 139.65 ? 49  GLU H O   1 
ATOM   321  C CB  . GLU A 1 49  ? 129.712 135.470 149.958 1.00 139.65 ? 49  GLU H CB  1 
ATOM   322  C CG  . GLU A 1 49  ? 129.757 135.593 151.463 1.00 139.65 ? 49  GLU H CG  1 
ATOM   323  C CD  . GLU A 1 49  ? 131.140 135.334 152.009 1.00 139.65 ? 49  GLU H CD  1 
ATOM   324  O OE1 . GLU A 1 49  ? 132.029 134.982 151.208 1.00 139.65 ? 49  GLU H OE1 1 
ATOM   325  O OE2 . GLU A 1 49  ? 131.336 135.475 153.234 1.00 139.65 ? 49  GLU H OE2 1 
ATOM   326  N N   . TRP A 1 50  ? 129.421 136.522 147.351 1.00 144.16 ? 50  TRP H N   1 
ATOM   327  C CA  . TRP A 1 50  ? 129.706 136.808 145.956 1.00 144.16 ? 50  TRP H CA  1 
ATOM   328  C C   . TRP A 1 50  ? 129.769 135.547 145.095 1.00 144.16 ? 50  TRP H C   1 
ATOM   329  O O   . TRP A 1 50  ? 129.828 134.419 145.580 1.00 144.16 ? 50  TRP H O   1 
ATOM   330  C CB  . TRP A 1 50  ? 131.048 137.522 145.867 1.00 144.16 ? 50  TRP H CB  1 
ATOM   331  C CG  . TRP A 1 50  ? 132.158 136.718 146.516 1.00 144.16 ? 50  TRP H CG  1 
ATOM   332  C CD1 . TRP A 1 50  ? 132.547 136.768 147.820 1.00 144.16 ? 50  TRP H CD1 1 
ATOM   333  C CD2 . TRP A 1 50  ? 132.990 135.741 145.892 1.00 144.16 ? 50  TRP H CD2 1 
ATOM   334  N NE1 . TRP A 1 50  ? 133.571 135.889 148.048 1.00 144.16 ? 50  TRP H NE1 1 
ATOM   335  C CE2 . TRP A 1 50  ? 133.863 135.245 146.876 1.00 144.16 ? 50  TRP H CE2 1 
ATOM   336  C CE3 . TRP A 1 50  ? 133.088 135.244 144.593 1.00 144.16 ? 50  TRP H CE3 1 
ATOM   337  C CZ2 . TRP A 1 50  ? 134.815 134.276 146.600 1.00 144.16 ? 50  TRP H CZ2 1 
ATOM   338  C CZ3 . TRP A 1 50  ? 134.029 134.280 144.321 1.00 144.16 ? 50  TRP H CZ3 1 
ATOM   339  C CH2 . TRP A 1 50  ? 134.880 133.806 145.319 1.00 144.16 ? 50  TRP H CH2 1 
ATOM   340  N N   . VAL A 1 51  ? 129.809 135.767 143.784 1.00 134.92 ? 51  VAL H N   1 
ATOM   341  C CA  . VAL A 1 51  ? 129.990 134.698 142.811 1.00 134.92 ? 51  VAL H CA  1 
ATOM   342  C C   . VAL A 1 51  ? 131.124 135.106 141.870 1.00 134.92 ? 51  VAL H C   1 
ATOM   343  O O   . VAL A 1 51  ? 131.286 136.293 141.564 1.00 134.92 ? 51  VAL H O   1 
ATOM   344  C CB  . VAL A 1 51  ? 128.685 134.393 142.043 1.00 134.92 ? 51  VAL H CB  1 
ATOM   345  C CG1 . VAL A 1 51  ? 128.225 135.565 141.201 1.00 134.92 ? 51  VAL H CG1 1 
ATOM   346  C CG2 . VAL A 1 51  ? 128.821 133.151 141.188 1.00 134.92 ? 51  VAL H CG2 1 
ATOM   347  N N   . ALA A 1 52  ? 131.978 134.152 141.506 1.00 133.26 ? 52  ALA H N   1 
ATOM   348  C CA  . ALA A 1 52  ? 132.900 134.298 140.384 1.00 133.26 ? 52  ALA H CA  1 
ATOM   349  C C   . ALA A 1 52  ? 132.603 133.125 139.464 1.00 133.26 ? 52  ALA H C   1 
ATOM   350  O O   . ALA A 1 52  ? 133.262 132.088 139.519 1.00 133.26 ? 52  ALA H O   1 
ATOM   351  C CB  . ALA A 1 52  ? 134.355 134.315 140.819 1.00 133.26 ? 52  ALA H CB  1 
ATOM   352  N N   . PHE A 1 53  ? 131.606 133.308 138.611 1.00 124.98 ? 53  PHE H N   1 
ATOM   353  C CA  . PHE A 1 53  ? 131.134 132.229 137.765 1.00 124.98 ? 53  PHE H CA  1 
ATOM   354  C C   . PHE A 1 53  ? 132.105 131.982 136.625 1.00 124.98 ? 53  PHE H C   1 
ATOM   355  O O   . PHE A 1 53  ? 132.459 132.899 135.882 1.00 124.98 ? 53  PHE H O   1 
ATOM   356  C CB  . PHE A 1 53  ? 129.755 132.581 137.226 1.00 124.98 ? 53  PHE H CB  1 
ATOM   357  C CG  . PHE A 1 53  ? 129.175 131.554 136.315 1.00 124.98 ? 53  PHE H CG  1 
ATOM   358  C CD1 . PHE A 1 53  ? 128.716 130.351 136.812 1.00 124.98 ? 53  PHE H CD1 1 
ATOM   359  C CD2 . PHE A 1 53  ? 129.049 131.811 134.963 1.00 124.98 ? 53  PHE H CD2 1 
ATOM   360  C CE1 . PHE A 1 53  ? 128.163 129.406 135.972 1.00 124.98 ? 53  PHE H CE1 1 
ATOM   361  C CE2 . PHE A 1 53  ? 128.496 130.876 134.117 1.00 124.98 ? 53  PHE H CE2 1 
ATOM   362  C CZ  . PHE A 1 53  ? 128.053 129.669 134.623 1.00 124.98 ? 53  PHE H CZ  1 
ATOM   363  N N   . ILE A 1 54  ? 132.544 130.739 136.491 1.00 121.92 ? 54  ILE H N   1 
ATOM   364  C CA  . ILE A 1 54  ? 133.422 130.355 135.402 1.00 121.92 ? 54  ILE H CA  1 
ATOM   365  C C   . ILE A 1 54  ? 132.529 129.862 134.269 1.00 121.92 ? 54  ILE H C   1 
ATOM   366  O O   . ILE A 1 54  ? 131.364 129.508 134.470 1.00 121.92 ? 54  ILE H O   1 
ATOM   367  C CB  . ILE A 1 54  ? 134.435 129.279 135.857 1.00 121.92 ? 54  ILE H CB  1 
ATOM   368  C CG1 . ILE A 1 54  ? 135.654 129.196 134.946 1.00 121.92 ? 54  ILE H CG1 1 
ATOM   369  C CG2 . ILE A 1 54  ? 133.792 127.945 135.919 1.00 121.92 ? 54  ILE H CG2 1 
ATOM   370  C CD1 . ILE A 1 54  ? 136.588 130.330 135.120 1.00 121.92 ? 54  ILE H CD1 1 
ATOM   371  N N   . SER A 1 55  ? 133.060 129.890 133.054 1.00 121.45 ? 55  SER H N   1 
ATOM   372  C CA  . SER A 1 55  ? 132.335 129.253 131.973 1.00 121.45 ? 55  SER H CA  1 
ATOM   373  C C   . SER A 1 55  ? 132.482 127.738 132.019 1.00 121.45 ? 55  SER H C   1 
ATOM   374  O O   . SER A 1 55  ? 133.227 127.170 132.817 1.00 121.45 ? 55  SER H O   1 
ATOM   375  C CB  . SER A 1 55  ? 132.828 129.752 130.627 1.00 121.45 ? 55  SER H CB  1 
ATOM   376  O OG  . SER A 1 55  ? 132.153 129.083 129.580 1.00 121.45 ? 55  SER H OG  1 
ATOM   377  N N   . ASN A 1 56  ? 131.743 127.086 131.126 1.00 114.80 ? 56  ASN H N   1 
ATOM   378  C CA  . ASN A 1 56  ? 131.947 125.667 130.871 1.00 114.80 ? 56  ASN H CA  1 
ATOM   379  C C   . ASN A 1 56  ? 133.317 125.419 130.263 1.00 114.80 ? 56  ASN H C   1 
ATOM   380  O O   . ASN A 1 56  ? 133.999 124.452 130.615 1.00 114.80 ? 56  ASN H O   1 
ATOM   381  C CB  . ASN A 1 56  ? 130.859 125.171 129.927 1.00 114.80 ? 56  ASN H CB  1 
ATOM   382  C CG  . ASN A 1 56  ? 130.855 123.669 129.756 1.00 114.80 ? 56  ASN H CG  1 
ATOM   383  O OD1 . ASN A 1 56  ? 131.537 122.929 130.464 1.00 114.80 ? 56  ASN H OD1 1 
ATOM   384  N ND2 . ASN A 1 56  ? 130.110 123.213 128.759 1.00 114.80 ? 56  ASN H ND2 1 
ATOM   385  N N   . LEU A 1 57  ? 133.739 126.296 129.359 1.00 108.59 ? 57  LEU H N   1 
ATOM   386  C CA  . LEU A 1 57  ? 134.943 126.107 128.566 1.00 108.59 ? 57  LEU H CA  1 
ATOM   387  C C   . LEU A 1 57  ? 136.017 127.118 128.922 1.00 108.59 ? 57  LEU H C   1 
ATOM   388  O O   . LEU A 1 57  ? 136.909 127.373 128.107 1.00 108.59 ? 57  LEU H O   1 
ATOM   389  C CB  . LEU A 1 57  ? 134.609 126.199 127.080 1.00 108.59 ? 57  LEU H CB  1 
ATOM   390  C CG  . LEU A 1 57  ? 134.109 124.972 126.322 1.00 108.59 ? 57  LEU H CG  1 
ATOM   391  C CD1 . LEU A 1 57  ? 132.759 124.491 126.786 1.00 108.59 ? 57  LEU H CD1 1 
ATOM   392  C CD2 . LEU A 1 57  ? 134.006 125.364 124.882 1.00 108.59 ? 57  LEU H CD2 1 
ATOM   393  N N   . ALA A 1 58  ? 135.916 127.710 130.117 1.00 113.79 ? 58  ALA H N   1 
ATOM   394  C CA  . ALA A 1 58  ? 136.799 128.767 130.620 1.00 113.79 ? 58  ALA H CA  1 
ATOM   395  C C   . ALA A 1 58  ? 136.850 129.971 129.687 1.00 113.79 ? 58  ALA H C   1 
ATOM   396  O O   . ALA A 1 58  ? 137.870 130.655 129.599 1.00 113.79 ? 58  ALA H O   1 
ATOM   397  C CB  . ALA A 1 58  ? 138.215 128.249 130.900 1.00 113.79 ? 58  ALA H CB  1 
ATOM   398  N N   . TYR A 1 59  ? 135.756 130.241 128.976 1.00 116.20 ? 59  TYR H N   1 
ATOM   399  C CA  . TYR A 1 59  ? 135.709 131.381 128.075 1.00 116.20 ? 59  TYR H CA  1 
ATOM   400  C C   . TYR A 1 59  ? 135.083 132.606 128.728 1.00 116.20 ? 59  TYR H C   1 
ATOM   401  O O   . TYR A 1 59  ? 135.749 133.629 128.907 1.00 116.20 ? 59  TYR H O   1 
ATOM   402  C CB  . TYR A 1 59  ? 134.939 131.030 126.803 1.00 116.20 ? 59  TYR H CB  1 
ATOM   403  C CG  . TYR A 1 59  ? 134.948 132.192 125.859 1.00 116.20 ? 59  TYR H CG  1 
ATOM   404  C CD1 . TYR A 1 59  ? 136.121 132.555 125.219 1.00 116.20 ? 59  TYR H CD1 1 
ATOM   405  C CD2 . TYR A 1 59  ? 133.801 132.944 125.622 1.00 116.20 ? 59  TYR H CD2 1 
ATOM   406  C CE1 . TYR A 1 59  ? 136.161 133.625 124.365 1.00 116.20 ? 59  TYR H CE1 1 
ATOM   407  C CE2 . TYR A 1 59  ? 133.831 134.026 124.762 1.00 116.20 ? 59  TYR H CE2 1 
ATOM   408  C CZ  . TYR A 1 59  ? 135.018 134.355 124.138 1.00 116.20 ? 59  TYR H CZ  1 
ATOM   409  O OH  . TYR A 1 59  ? 135.085 135.419 123.282 1.00 116.20 ? 59  TYR H OH  1 
ATOM   410  N N   . SER A 1 60  ? 133.809 132.521 129.090 1.00 121.73 ? 60  SER H N   1 
ATOM   411  C CA  . SER A 1 60  ? 133.147 133.624 129.771 1.00 121.73 ? 60  SER H CA  1 
ATOM   412  C C   . SER A 1 60  ? 133.518 133.545 131.240 1.00 121.73 ? 60  SER H C   1 
ATOM   413  O O   . SER A 1 60  ? 133.087 132.633 131.956 1.00 121.73 ? 60  SER H O   1 
ATOM   414  C CB  . SER A 1 60  ? 131.636 133.572 129.581 1.00 121.73 ? 60  SER H CB  1 
ATOM   415  O OG  . SER A 1 60  ? 131.073 132.494 130.297 1.00 121.73 ? 60  SER H OG  1 
ATOM   416  N N   . ILE A 1 61  ? 134.359 134.469 131.674 1.00 129.39 ? 61  ILE H N   1 
ATOM   417  C CA  . ILE A 1 61  ? 134.762 134.582 133.064 1.00 129.39 ? 61  ILE H CA  1 
ATOM   418  C C   . ILE A 1 61  ? 134.310 135.947 133.546 1.00 129.39 ? 61  ILE H C   1 
ATOM   419  O O   . ILE A 1 61  ? 134.292 136.908 132.769 1.00 129.39 ? 61  ILE H O   1 
ATOM   420  C CB  . ILE A 1 61  ? 136.287 134.372 133.231 1.00 129.39 ? 61  ILE H CB  1 
ATOM   421  C CG1 . ILE A 1 61  ? 137.132 135.401 132.466 1.00 129.39 ? 61  ILE H CG1 1 
ATOM   422  C CG2 . ILE A 1 61  ? 136.684 133.035 132.678 1.00 129.39 ? 61  ILE H CG2 1 
ATOM   423  C CD1 . ILE A 1 61  ? 137.680 136.573 133.295 1.00 129.39 ? 61  ILE H CD1 1 
ATOM   424  N N   . TYR A 1 62  ? 133.901 136.023 134.806 1.00 136.25 ? 62  TYR H N   1 
ATOM   425  C CA  . TYR A 1 62  ? 133.741 137.317 135.454 1.00 136.25 ? 62  TYR H CA  1 
ATOM   426  C C   . TYR A 1 62  ? 133.886 137.127 136.950 1.00 136.25 ? 62  TYR H C   1 
ATOM   427  O O   . TYR A 1 62  ? 133.470 136.099 137.492 1.00 136.25 ? 62  TYR H O   1 
ATOM   428  C CB  . TYR A 1 62  ? 132.399 137.990 135.120 1.00 136.25 ? 62  TYR H CB  1 
ATOM   429  C CG  . TYR A 1 62  ? 131.161 137.218 135.480 1.00 136.25 ? 62  TYR H CG  1 
ATOM   430  C CD1 . TYR A 1 62  ? 130.585 137.334 136.740 1.00 136.25 ? 62  TYR H CD1 1 
ATOM   431  C CD2 . TYR A 1 62  ? 130.544 136.399 134.547 1.00 136.25 ? 62  TYR H CD2 1 
ATOM   432  C CE1 . TYR A 1 62  ? 129.458 136.634 137.074 1.00 136.25 ? 62  TYR H CE1 1 
ATOM   433  C CE2 . TYR A 1 62  ? 129.399 135.702 134.867 1.00 136.25 ? 62  TYR H CE2 1 
ATOM   434  C CZ  . TYR A 1 62  ? 128.860 135.828 136.134 1.00 136.25 ? 62  TYR H CZ  1 
ATOM   435  O OH  . TYR A 1 62  ? 127.723 135.142 136.479 1.00 136.25 ? 62  TYR H OH  1 
ATOM   436  N N   . TYR A 1 63  ? 134.469 138.119 137.603 1.00 135.50 ? 63  TYR H N   1 
ATOM   437  C CA  . TYR A 1 63  ? 134.605 138.134 139.042 1.00 135.50 ? 63  TYR H CA  1 
ATOM   438  C C   . TYR A 1 63  ? 133.611 139.130 139.617 1.00 135.50 ? 63  TYR H C   1 
ATOM   439  O O   . TYR A 1 63  ? 132.972 139.897 138.896 1.00 135.50 ? 63  TYR H O   1 
ATOM   440  C CB  . TYR A 1 63  ? 136.040 138.476 139.431 1.00 135.50 ? 63  TYR H CB  1 
ATOM   441  C CG  . TYR A 1 63  ? 137.030 137.475 138.900 1.00 135.50 ? 63  TYR H CG  1 
ATOM   442  C CD1 . TYR A 1 63  ? 137.198 136.248 139.517 1.00 135.50 ? 63  TYR H CD1 1 
ATOM   443  C CD2 . TYR A 1 63  ? 137.791 137.754 137.774 1.00 135.50 ? 63  TYR H CD2 1 
ATOM   444  C CE1 . TYR A 1 63  ? 138.095 135.322 139.028 1.00 135.50 ? 63  TYR H CE1 1 
ATOM   445  C CE2 . TYR A 1 63  ? 138.692 136.834 137.278 1.00 135.50 ? 63  TYR H CE2 1 
ATOM   446  C CZ  . TYR A 1 63  ? 138.841 135.620 137.912 1.00 135.50 ? 63  TYR H CZ  1 
ATOM   447  O OH  . TYR A 1 63  ? 139.739 134.699 137.428 1.00 135.50 ? 63  TYR H OH  1 
ATOM   448  N N   . ALA A 1 64  ? 133.484 139.121 140.930 1.00 142.54 ? 64  ALA H N   1 
ATOM   449  C CA  . ALA A 1 64  ? 132.566 140.015 141.615 1.00 142.54 ? 64  ALA H CA  1 
ATOM   450  C C   . ALA A 1 64  ? 133.292 141.315 141.957 1.00 142.54 ? 64  ALA H C   1 
ATOM   451  O O   . ALA A 1 64  ? 134.349 141.615 141.395 1.00 142.54 ? 64  ALA H O   1 
ATOM   452  C CB  . ALA A 1 64  ? 131.982 139.320 142.840 1.00 142.54 ? 64  ALA H CB  1 
ATOM   453  N N   . ASP A 1 65  ? 132.712 142.112 142.859 1.00 144.66 ? 65  ASP H N   1 
ATOM   454  C CA  . ASP A 1 65  ? 133.248 143.432 143.164 1.00 144.66 ? 65  ASP H CA  1 
ATOM   455  C C   . ASP A 1 65  ? 134.590 143.366 143.878 1.00 144.66 ? 65  ASP H C   1 
ATOM   456  O O   . ASP A 1 65  ? 135.435 144.246 143.684 1.00 144.66 ? 65  ASP H O   1 
ATOM   457  C CB  . ASP A 1 65  ? 132.256 144.213 144.013 1.00 144.66 ? 65  ASP H CB  1 
ATOM   458  C CG  . ASP A 1 65  ? 132.697 145.631 144.245 1.00 144.66 ? 65  ASP H CG  1 
ATOM   459  O OD1 . ASP A 1 65  ? 132.585 146.443 143.305 1.00 144.66 ? 65  ASP H OD1 1 
ATOM   460  O OD2 . ASP A 1 65  ? 133.179 145.927 145.356 1.00 144.66 ? 65  ASP H OD2 1 
ATOM   461  N N   . THR A 1 66  ? 134.815 142.342 144.698 1.00 146.31 ? 66  THR H N   1 
ATOM   462  C CA  . THR A 1 66  ? 136.089 142.207 145.401 1.00 146.31 ? 66  THR H CA  1 
ATOM   463  C C   . THR A 1 66  ? 137.059 141.451 144.499 1.00 146.31 ? 66  THR H C   1 
ATOM   464  O O   . THR A 1 66  ? 137.359 140.271 144.690 1.00 146.31 ? 66  THR H O   1 
ATOM   465  C CB  . THR A 1 66  ? 135.901 141.510 146.738 1.00 146.31 ? 66  THR H CB  1 
ATOM   466  O OG1 . THR A 1 66  ? 135.454 140.170 146.517 1.00 146.31 ? 66  THR H OG1 1 
ATOM   467  C CG2 . THR A 1 66  ? 134.868 142.255 147.568 1.00 146.31 ? 66  THR H CG2 1 
ATOM   468  N N   . VAL A 1 67  ? 137.551 142.159 143.489 1.00 142.94 ? 67  VAL H N   1 
ATOM   469  C CA  . VAL A 1 67  ? 138.570 141.648 142.584 1.00 142.94 ? 67  VAL H CA  1 
ATOM   470  C C   . VAL A 1 67  ? 139.844 142.461 142.811 1.00 142.94 ? 67  VAL H C   1 
ATOM   471  O O   . VAL A 1 67  ? 139.987 143.607 142.365 1.00 142.94 ? 67  VAL H O   1 
ATOM   472  C CB  . VAL A 1 67  ? 138.100 141.638 141.117 1.00 142.94 ? 67  VAL H CB  1 
ATOM   473  C CG1 . VAL A 1 67  ? 137.403 142.946 140.692 1.00 142.94 ? 67  VAL H CG1 1 
ATOM   474  C CG2 . VAL A 1 67  ? 139.260 141.306 140.180 1.00 142.94 ? 67  VAL H CG2 1 
ATOM   475  N N   . THR A 1 68  ? 140.755 141.888 143.588 1.00 146.04 ? 68  THR H N   1 
ATOM   476  C CA  . THR A 1 68  ? 142.114 142.394 143.698 1.00 146.04 ? 68  THR H CA  1 
ATOM   477  C C   . THR A 1 68  ? 143.136 141.360 143.255 1.00 146.04 ? 68  THR H C   1 
ATOM   478  O O   . THR A 1 68  ? 144.013 141.668 142.440 1.00 146.04 ? 68  THR H O   1 
ATOM   479  C CB  . THR A 1 68  ? 142.386 142.894 145.137 1.00 146.04 ? 68  THR H CB  1 
ATOM   480  O OG1 . THR A 1 68  ? 143.779 143.182 145.307 1.00 146.04 ? 68  THR H OG1 1 
ATOM   481  C CG2 . THR A 1 68  ? 141.873 141.938 146.226 1.00 146.04 ? 68  THR H CG2 1 
ATOM   482  N N   . GLY A 1 69  ? 143.035 140.136 143.756 1.00 139.74 ? 69  GLY H N   1 
ATOM   483  C CA  . GLY A 1 69  ? 143.651 138.983 143.151 1.00 139.74 ? 69  GLY H CA  1 
ATOM   484  C C   . GLY A 1 69  ? 142.507 138.061 142.809 1.00 139.74 ? 69  GLY H C   1 
ATOM   485  O O   . GLY A 1 69  ? 141.656 138.424 141.990 1.00 139.74 ? 69  GLY H O   1 
ATOM   486  N N   . ARG A 1 70  ? 142.469 136.897 143.464 1.00 140.70 ? 70  ARG H N   1 
ATOM   487  C CA  . ARG A 1 70  ? 141.322 135.987 143.500 1.00 140.70 ? 70  ARG H CA  1 
ATOM   488  C C   . ARG A 1 70  ? 140.926 135.532 142.092 1.00 140.70 ? 70  ARG H C   1 
ATOM   489  O O   . ARG A 1 70  ? 139.864 135.864 141.574 1.00 140.70 ? 70  ARG H O   1 
ATOM   490  C CB  . ARG A 1 70  ? 140.142 136.636 144.234 1.00 140.70 ? 70  ARG H CB  1 
ATOM   491  C CG  . ARG A 1 70  ? 140.384 136.954 145.718 1.00 140.70 ? 70  ARG H CG  1 
ATOM   492  C CD  . ARG A 1 70  ? 140.586 135.707 146.584 1.00 140.70 ? 70  ARG H CD  1 
ATOM   493  N NE  . ARG A 1 70  ? 141.992 135.319 146.695 1.00 140.70 ? 70  ARG H NE  1 
ATOM   494  C CZ  . ARG A 1 70  ? 142.417 134.150 147.164 1.00 140.70 ? 70  ARG H CZ  1 
ATOM   495  N NH1 . ARG A 1 70  ? 141.547 133.240 147.576 1.00 140.70 ? 70  ARG H NH1 1 
ATOM   496  N NH2 . ARG A 1 70  ? 143.716 133.890 147.218 1.00 140.70 ? 70  ARG H NH2 1 
ATOM   497  N N   . PHE A 1 71  ? 141.836 134.789 141.475 1.00 141.26 ? 71  PHE H N   1 
ATOM   498  C CA  . PHE A 1 71  ? 141.665 134.350 140.098 1.00 141.26 ? 71  PHE H CA  1 
ATOM   499  C C   . PHE A 1 71  ? 141.103 132.937 140.048 1.00 141.26 ? 71  PHE H C   1 
ATOM   500  O O   . PHE A 1 71  ? 141.545 132.054 140.787 1.00 141.26 ? 71  PHE H O   1 
ATOM   501  C CB  . PHE A 1 71  ? 142.986 134.406 139.334 1.00 141.26 ? 71  PHE H CB  1 
ATOM   502  C CG  . PHE A 1 71  ? 143.458 135.799 139.034 1.00 141.26 ? 71  PHE H CG  1 
ATOM   503  C CD1 . PHE A 1 71  ? 142.596 136.881 139.139 1.00 141.26 ? 71  PHE H CD1 1 
ATOM   504  C CD2 . PHE A 1 71  ? 144.768 136.026 138.648 1.00 141.26 ? 71  PHE H CD2 1 
ATOM   505  C CE1 . PHE A 1 71  ? 143.034 138.162 138.866 1.00 141.26 ? 71  PHE H CE1 1 
ATOM   506  C CE2 . PHE A 1 71  ? 145.213 137.306 138.372 1.00 141.26 ? 71  PHE H CE2 1 
ATOM   507  C CZ  . PHE A 1 71  ? 144.342 138.376 138.481 1.00 141.26 ? 71  PHE H CZ  1 
ATOM   508  N N   . THR A 1 72  ? 140.130 132.733 139.164 1.00 132.40 ? 72  THR H N   1 
ATOM   509  C CA  . THR A 1 72  ? 139.499 131.436 138.965 1.00 132.40 ? 72  THR H CA  1 
ATOM   510  C C   . THR A 1 72  ? 140.063 130.814 137.697 1.00 132.40 ? 72  THR H C   1 
ATOM   511  O O   . THR A 1 72  ? 140.185 131.491 136.673 1.00 132.40 ? 72  THR H O   1 
ATOM   512  C CB  . THR A 1 72  ? 137.980 131.579 138.851 1.00 132.40 ? 72  THR H CB  1 
ATOM   513  O OG1 . THR A 1 72  ? 137.479 132.276 139.995 1.00 132.40 ? 72  THR H OG1 1 
ATOM   514  C CG2 . THR A 1 72  ? 137.311 130.220 138.801 1.00 132.40 ? 72  THR H CG2 1 
ATOM   515  N N   . ILE A 1 73  ? 140.419 129.539 137.768 1.00 134.25 ? 73  ILE H N   1 
ATOM   516  C CA  . ILE A 1 73  ? 140.945 128.857 136.603 1.00 134.25 ? 73  ILE H CA  1 
ATOM   517  C C   . ILE A 1 73  ? 140.444 127.412 136.614 1.00 134.25 ? 73  ILE H C   1 
ATOM   518  O O   . ILE A 1 73  ? 140.212 126.831 137.673 1.00 134.25 ? 73  ILE H O   1 
ATOM   519  C CB  . ILE A 1 73  ? 142.492 128.977 136.560 1.00 134.25 ? 73  ILE H CB  1 
ATOM   520  C CG1 . ILE A 1 73  ? 143.050 128.570 135.194 1.00 134.25 ? 73  ILE H CG1 1 
ATOM   521  C CG2 . ILE A 1 73  ? 143.150 128.213 137.698 1.00 134.25 ? 73  ILE H CG2 1 
ATOM   522  C CD1 . ILE A 1 73  ? 142.659 129.508 134.078 1.00 134.25 ? 73  ILE H CD1 1 
HETATM 523  N N   . SEP A 1 74  ? 140.224 126.854 135.430 1.00 134.17 ? 74  SEP H N   1 
HETATM 524  C CA  . SEP A 1 74  ? 139.699 125.504 135.304 1.00 134.17 ? 74  SEP H CA  1 
HETATM 525  C CB  . SEP A 1 74  ? 138.276 125.542 134.743 1.00 134.17 ? 74  SEP H CB  1 
HETATM 526  O OG  . SEP A 1 74  ? 137.769 124.242 134.495 1.00 134.17 ? 74  SEP H OG  1 
HETATM 527  C C   . SEP A 1 74  ? 140.604 124.665 134.413 1.00 134.17 ? 74  SEP H C   1 
HETATM 528  O O   . SEP A 1 74  ? 140.993 125.097 133.331 1.00 134.17 ? 74  SEP H O   1 
HETATM 529  P P   . SEP A 1 74  ? 136.248 124.346 133.977 1.00 134.17 ? 74  SEP H P   1 
HETATM 530  O O1P . SEP A 1 74  ? 136.196 125.046 132.532 1.00 134.17 ? 74  SEP H O1P 1 
HETATM 531  O O2P . SEP A 1 74  ? 135.578 122.890 133.882 1.00 134.17 ? 74  SEP H O2P 1 
HETATM 532  O O3P . SEP A 1 74  ? 135.395 125.222 135.009 1.00 134.17 ? 74  SEP H O3P 1 
ATOM   533  N N   . ARG A 1 75  ? 140.951 123.469 134.875 1.00 137.52 ? 75  ARG H N   1 
ATOM   534  C CA  . ARG A 1 75  ? 141.789 122.566 134.095 1.00 137.52 ? 75  ARG H CA  1 
ATOM   535  C C   . ARG A 1 75  ? 141.186 121.173 134.053 1.00 137.52 ? 75  ARG H C   1 
ATOM   536  O O   . ARG A 1 75  ? 140.968 120.553 135.089 1.00 137.52 ? 75  ARG H O   1 
ATOM   537  C CB  . ARG A 1 75  ? 143.200 122.501 134.673 1.00 137.52 ? 75  ARG H CB  1 
ATOM   538  C CG  . ARG A 1 75  ? 143.993 123.783 134.527 1.00 137.52 ? 75  ARG H CG  1 
ATOM   539  C CD  . ARG A 1 75  ? 145.363 123.657 135.165 1.00 137.52 ? 75  ARG H CD  1 
ATOM   540  N NE  . ARG A 1 75  ? 146.120 124.902 135.075 1.00 137.52 ? 75  ARG H NE  1 
ATOM   541  C CZ  . ARG A 1 75  ? 147.320 125.088 135.614 1.00 137.52 ? 75  ARG H CZ  1 
ATOM   542  N NH1 . ARG A 1 75  ? 147.907 124.109 136.288 1.00 137.52 ? 75  ARG H NH1 1 
ATOM   543  N NH2 . ARG A 1 75  ? 147.934 126.256 135.480 1.00 137.52 ? 75  ARG H NH2 1 
ATOM   544  N N   . GLU A 1 76  ? 140.924 120.678 132.849 1.00 134.74 ? 76  GLU H N   1 
ATOM   545  C CA  . GLU A 1 76  ? 140.307 119.364 132.675 1.00 134.74 ? 76  GLU H CA  1 
ATOM   546  C C   . GLU A 1 76  ? 141.351 118.267 132.500 1.00 134.74 ? 76  GLU H C   1 
ATOM   547  O O   . GLU A 1 76  ? 141.304 117.484 131.553 1.00 134.74 ? 76  GLU H O   1 
ATOM   548  C CB  . GLU A 1 76  ? 139.350 119.393 131.491 1.00 134.74 ? 76  GLU H CB  1 
ATOM   549  C CG  . GLU A 1 76  ? 138.102 120.227 131.698 1.00 134.74 ? 76  GLU H CG  1 
ATOM   550  C CD  . GLU A 1 76  ? 138.309 121.690 131.378 1.00 134.74 ? 76  GLU H CD  1 
ATOM   551  O OE1 . GLU A 1 76  ? 139.422 122.060 130.955 1.00 134.74 ? 76  GLU H OE1 1 
ATOM   552  O OE2 . GLU A 1 76  ? 137.355 122.471 131.543 1.00 134.74 ? 76  GLU H OE2 1 
ATOM   553  N N   . ASN A 1 77  ? 142.308 118.199 133.420 1.00 137.59 ? 77  ASN H N   1 
ATOM   554  C CA  . ASN A 1 77  ? 143.278 117.113 133.432 1.00 137.59 ? 77  ASN H CA  1 
ATOM   555  C C   . ASN A 1 77  ? 142.992 116.101 134.533 1.00 137.59 ? 77  ASN H C   1 
ATOM   556  O O   . ASN A 1 77  ? 142.947 114.895 134.276 1.00 137.59 ? 77  ASN H O   1 
ATOM   557  C CB  . ASN A 1 77  ? 144.708 117.671 133.547 1.00 137.59 ? 77  ASN H CB  1 
ATOM   558  C CG  . ASN A 1 77  ? 144.902 118.608 134.737 1.00 137.59 ? 77  ASN H CG  1 
ATOM   559  O OD1 . ASN A 1 77  ? 143.997 118.811 135.547 1.00 137.59 ? 77  ASN H OD1 1 
ATOM   560  N ND2 . ASN A 1 77  ? 146.099 119.174 134.849 1.00 137.59 ? 77  ASN H ND2 1 
ATOM   561  N N   . ALA A 1 78  ? 142.779 116.574 135.758 1.00 137.75 ? 78  ALA H N   1 
ATOM   562  C CA  . ALA A 1 78  ? 142.357 115.732 136.867 1.00 137.75 ? 78  ALA H CA  1 
ATOM   563  C C   . ALA A 1 78  ? 140.984 116.146 137.369 1.00 137.75 ? 78  ALA H C   1 
ATOM   564  O O   . ALA A 1 78  ? 140.657 115.906 138.536 1.00 137.75 ? 78  ALA H O   1 
ATOM   565  C CB  . ALA A 1 78  ? 143.381 115.780 138.001 1.00 137.75 ? 78  ALA H CB  1 
ATOM   566  N N   . LYS A 1 79  ? 140.201 116.796 136.503 1.00 132.98 ? 79  LYS H N   1 
ATOM   567  C CA  . LYS A 1 79  ? 138.831 117.241 136.753 1.00 132.98 ? 79  LYS H CA  1 
ATOM   568  C C   . LYS A 1 79  ? 138.721 118.197 137.933 1.00 132.98 ? 79  LYS H C   1 
ATOM   569  O O   . LYS A 1 79  ? 137.671 118.276 138.573 1.00 132.98 ? 79  LYS H O   1 
ATOM   570  C CB  . LYS A 1 79  ? 137.883 116.052 136.942 1.00 132.98 ? 79  LYS H CB  1 
ATOM   571  C CG  . LYS A 1 79  ? 137.664 115.250 135.679 1.00 132.98 ? 79  LYS H CG  1 
ATOM   572  C CD  . LYS A 1 79  ? 136.682 114.124 135.911 1.00 132.98 ? 79  LYS H CD  1 
ATOM   573  C CE  . LYS A 1 79  ? 136.478 113.312 134.645 1.00 132.98 ? 79  LYS H CE  1 
ATOM   574  N NZ  . LYS A 1 79  ? 135.526 112.187 134.853 1.00 132.98 ? 79  LYS H NZ  1 
ATOM   575  N N   . ASN A 1 80  ? 139.780 118.935 138.232 1.00 136.68 ? 80  ASN H N   1 
ATOM   576  C CA  . ASN A 1 80  ? 139.795 119.859 139.354 1.00 136.68 ? 80  ASN H CA  1 
ATOM   577  C C   . ASN A 1 80  ? 139.812 121.299 138.862 1.00 136.68 ? 80  ASN H C   1 
ATOM   578  O O   . ASN A 1 80  ? 140.152 121.588 137.714 1.00 136.68 ? 80  ASN H O   1 
ATOM   579  C CB  . ASN A 1 80  ? 140.997 119.585 140.268 1.00 136.68 ? 80  ASN H CB  1 
ATOM   580  C CG  . ASN A 1 80  ? 142.323 119.568 139.522 1.00 136.68 ? 80  ASN H CG  1 
ATOM   581  O OD1 . ASN A 1 80  ? 142.378 119.750 138.306 1.00 136.68 ? 80  ASN H OD1 1 
ATOM   582  N ND2 . ASN A 1 80  ? 143.407 119.364 140.261 1.00 136.68 ? 80  ASN H ND2 1 
ATOM   583  N N   . THR A 1 81  ? 139.433 122.208 139.751 1.00 134.49 ? 81  THR H N   1 
ATOM   584  C CA  . THR A 1 81  ? 139.628 123.624 139.513 1.00 134.49 ? 81  THR H CA  1 
ATOM   585  C C   . THR A 1 81  ? 140.518 124.196 140.605 1.00 134.49 ? 81  THR H C   1 
ATOM   586  O O   . THR A 1 81  ? 140.542 123.708 141.742 1.00 134.49 ? 81  THR H O   1 
ATOM   587  C CB  . THR A 1 81  ? 138.301 124.403 139.426 1.00 134.49 ? 81  THR H CB  1 
ATOM   588  O OG1 . THR A 1 81  ? 138.572 125.765 139.077 1.00 134.49 ? 81  THR H OG1 1 
ATOM   589  C CG2 . THR A 1 81  ? 137.536 124.369 140.729 1.00 134.49 ? 81  THR H CG2 1 
ATOM   590  N N   . LEU A 1 82  ? 141.284 125.210 140.224 1.00 131.87 ? 82  LEU H N   1 
ATOM   591  C CA  . LEU A 1 82  ? 142.196 125.905 141.111 1.00 131.87 ? 82  LEU H CA  1 
ATOM   592  C C   . LEU A 1 82  ? 141.711 127.334 141.282 1.00 131.87 ? 82  LEU H C   1 
ATOM   593  O O   . LEU A 1 82  ? 141.067 127.896 140.392 1.00 131.87 ? 82  LEU H O   1 
ATOM   594  C CB  . LEU A 1 82  ? 143.617 125.895 140.547 1.00 131.87 ? 82  LEU H CB  1 
ATOM   595  C CG  . LEU A 1 82  ? 144.234 124.513 140.345 1.00 131.87 ? 82  LEU H CG  1 
ATOM   596  C CD1 . LEU A 1 82  ? 145.561 124.618 139.623 1.00 131.87 ? 82  LEU H CD1 1 
ATOM   597  C CD2 . LEU A 1 82  ? 144.407 123.810 141.672 1.00 131.87 ? 82  LEU H CD2 1 
ATOM   598  N N   . TYR A 1 83  ? 142.015 127.921 142.433 1.00 142.36 ? 83  TYR H N   1 
ATOM   599  C CA  . TYR A 1 83  ? 141.529 129.264 142.724 1.00 142.36 ? 83  TYR H CA  1 
ATOM   600  C C   . TYR A 1 83  ? 142.532 129.996 143.599 1.00 142.36 ? 83  TYR H C   1 
ATOM   601  O O   . TYR A 1 83  ? 142.870 129.520 144.685 1.00 142.36 ? 83  TYR H O   1 
ATOM   602  C CB  . TYR A 1 83  ? 140.168 129.191 143.402 1.00 142.36 ? 83  TYR H CB  1 
ATOM   603  C CG  . TYR A 1 83  ? 139.591 130.531 143.736 1.00 142.36 ? 83  TYR H CG  1 
ATOM   604  C CD1 . TYR A 1 83  ? 139.073 131.348 142.746 1.00 142.36 ? 83  TYR H CD1 1 
ATOM   605  C CD2 . TYR A 1 83  ? 139.554 130.978 145.046 1.00 142.36 ? 83  TYR H CD2 1 
ATOM   606  C CE1 . TYR A 1 83  ? 138.542 132.580 143.052 1.00 142.36 ? 83  TYR H CE1 1 
ATOM   607  C CE2 . TYR A 1 83  ? 139.023 132.205 145.363 1.00 142.36 ? 83  TYR H CE2 1 
ATOM   608  C CZ  . TYR A 1 83  ? 138.519 133.002 144.363 1.00 142.36 ? 83  TYR H CZ  1 
ATOM   609  O OH  . TYR A 1 83  ? 137.989 134.226 144.683 1.00 142.36 ? 83  TYR H OH  1 
ATOM   610  N N   . LEU A 1 84  ? 142.997 131.152 143.141 1.00 143.63 ? 84  LEU H N   1 
ATOM   611  C CA  . LEU A 1 84  ? 143.979 131.914 143.903 1.00 143.63 ? 84  LEU H CA  1 
ATOM   612  C C   . LEU A 1 84  ? 143.720 133.413 143.848 1.00 143.63 ? 84  LEU H C   1 
ATOM   613  O O   . LEU A 1 84  ? 144.330 134.180 144.592 1.00 143.63 ? 84  LEU H O   1 
ATOM   614  C CB  . LEU A 1 84  ? 145.392 131.587 143.408 1.00 143.63 ? 84  LEU H CB  1 
ATOM   615  C CG  . LEU A 1 84  ? 145.797 131.787 141.944 1.00 143.63 ? 84  LEU H CG  1 
ATOM   616  C CD1 . LEU A 1 84  ? 146.384 133.166 141.658 1.00 143.63 ? 84  LEU H CD1 1 
ATOM   617  C CD2 . LEU A 1 84  ? 146.772 130.699 141.525 1.00 143.63 ? 84  LEU H CD2 1 
ATOM   618  N N   . TYR A 1 98  ? 133.151 127.733 149.687 1.00 131.85 ? 98  TYR H N   1 
ATOM   619  C CA  . TYR A 1 98  ? 132.378 126.662 149.065 1.00 131.85 ? 98  TYR H CA  1 
ATOM   620  C C   . TYR A 1 98  ? 132.622 126.602 147.563 1.00 131.85 ? 98  TYR H C   1 
ATOM   621  O O   . TYR A 1 98  ? 132.799 127.626 146.909 1.00 131.85 ? 98  TYR H O   1 
ATOM   622  C CB  . TYR A 1 98  ? 130.881 126.835 149.319 1.00 131.85 ? 98  TYR H CB  1 
ATOM   623  C CG  . TYR A 1 98  ? 130.434 126.617 150.740 1.00 131.85 ? 98  TYR H CG  1 
ATOM   624  C CD1 . TYR A 1 98  ? 131.252 125.985 151.665 1.00 131.85 ? 98  TYR H CD1 1 
ATOM   625  C CD2 . TYR A 1 98  ? 129.183 127.042 151.152 1.00 131.85 ? 98  TYR H CD2 1 
ATOM   626  C CE1 . TYR A 1 98  ? 130.833 125.789 152.967 1.00 131.85 ? 98  TYR H CE1 1 
ATOM   627  C CE2 . TYR A 1 98  ? 128.756 126.852 152.445 1.00 131.85 ? 98  TYR H CE2 1 
ATOM   628  C CZ  . TYR A 1 98  ? 129.584 126.226 153.347 1.00 131.85 ? 98  TYR H CZ  1 
ATOM   629  O OH  . TYR A 1 98  ? 129.159 126.036 154.637 1.00 131.85 ? 98  TYR H OH  1 
ATOM   630  N N   . CYS A 1 99  ? 132.589 125.392 147.027 1.00 131.96 ? 99  CYS H N   1 
ATOM   631  C CA  . CYS A 1 99  ? 132.878 125.108 145.628 1.00 131.96 ? 99  CYS H CA  1 
ATOM   632  C C   . CYS A 1 99  ? 131.645 124.449 145.023 1.00 131.96 ? 99  CYS H C   1 
ATOM   633  O O   . CYS A 1 99  ? 131.422 123.252 145.212 1.00 131.96 ? 99  CYS H O   1 
ATOM   634  C CB  . CYS A 1 99  ? 134.107 124.213 145.535 1.00 131.96 ? 99  CYS H CB  1 
ATOM   635  S SG  . CYS A 1 99  ? 134.560 123.729 143.880 1.00 131.96 ? 99  CYS H SG  1 
ATOM   636  N N   . ALA A 1 100 ? 130.855 125.214 144.275 1.00 125.07 ? 100 ALA H N   1 
ATOM   637  C CA  . ALA A 1 100 ? 129.578 124.719 143.786 1.00 125.07 ? 100 ALA H CA  1 
ATOM   638  C C   . ALA A 1 100 ? 129.546 124.734 142.264 1.00 125.07 ? 100 ALA H C   1 
ATOM   639  O O   . ALA A 1 100 ? 130.394 125.348 141.620 1.00 125.07 ? 100 ALA H O   1 
ATOM   640  C CB  . ALA A 1 100 ? 128.428 125.544 144.349 1.00 125.07 ? 100 ALA H CB  1 
ATOM   641  N N   . ARG A 1 101 ? 128.571 124.031 141.685 1.00 125.59 ? 101 ARG H N   1 
ATOM   642  C CA  . ARG A 1 101 ? 128.431 123.948 140.235 1.00 125.59 ? 101 ARG H CA  1 
ATOM   643  C C   . ARG A 1 101 ? 126.973 124.052 139.815 1.00 125.59 ? 101 ARG H C   1 
ATOM   644  O O   . ARG A 1 101 ? 126.072 123.621 140.540 1.00 125.59 ? 101 ARG H O   1 
ATOM   645  C CB  . ARG A 1 101 ? 129.001 122.647 139.668 1.00 125.59 ? 101 ARG H CB  1 
ATOM   646  C CG  . ARG A 1 101 ? 128.338 121.410 140.229 1.00 125.59 ? 101 ARG H CG  1 
ATOM   647  C CD  . ARG A 1 101 ? 128.734 120.154 139.491 1.00 125.59 ? 101 ARG H CD  1 
ATOM   648  N NE  . ARG A 1 101 ? 128.107 120.094 138.176 1.00 125.59 ? 101 ARG H NE  1 
ATOM   649  C CZ  . ARG A 1 101 ? 126.883 119.618 137.968 1.00 125.59 ? 101 ARG H CZ  1 
ATOM   650  N NH1 . ARG A 1 101 ? 126.173 119.159 138.984 1.00 125.59 ? 101 ARG H NH1 1 
ATOM   651  N NH2 . ARG A 1 101 ? 126.366 119.593 136.754 1.00 125.59 ? 101 ARG H NH2 1 
ATOM   652  N N   . GLN A 1 102 ? 126.751 124.608 138.626 1.00 123.40 ? 102 GLN H N   1 
ATOM   653  C CA  . GLN A 1 102 ? 125.406 124.791 138.106 1.00 123.40 ? 102 GLN H CA  1 
ATOM   654  C C   . GLN A 1 102 ? 124.914 123.510 137.441 1.00 123.40 ? 102 GLN H C   1 
ATOM   655  O O   . GLN A 1 102 ? 125.569 122.464 137.474 1.00 123.40 ? 102 GLN H O   1 
ATOM   656  C CB  . GLN A 1 102 ? 125.367 125.959 137.130 1.00 123.40 ? 102 GLN H CB  1 
ATOM   657  C CG  . GLN A 1 102 ? 126.153 125.720 135.867 1.00 123.40 ? 102 GLN H CG  1 
ATOM   658  C CD  . GLN A 1 102 ? 126.035 126.864 134.895 1.00 123.40 ? 102 GLN H CD  1 
ATOM   659  O OE1 . GLN A 1 102 ? 125.326 127.831 135.146 1.00 123.40 ? 102 GLN H OE1 1 
ATOM   660  N NE2 . GLN A 1 102 ? 126.723 126.758 133.769 1.00 123.40 ? 102 GLN H NE2 1 
ATOM   661  N N   . ASN A 1 103 ? 123.737 123.598 136.830 1.00 125.00 ? 103 ASN H N   1 
ATOM   662  C CA  . ASN A 1 103 ? 123.102 122.453 136.199 1.00 125.00 ? 103 ASN H CA  1 
ATOM   663  C C   . ASN A 1 103 ? 123.501 122.342 134.730 1.00 125.00 ? 103 ASN H C   1 
ATOM   664  O O   . ASN A 1 103 ? 124.412 123.019 134.251 1.00 125.00 ? 103 ASN H O   1 
ATOM   665  C CB  . ASN A 1 103 ? 121.589 122.544 136.315 1.00 125.00 ? 103 ASN H CB  1 
ATOM   666  C CG  . ASN A 1 103 ? 121.057 123.830 135.755 1.00 125.00 ? 103 ASN H CG  1 
ATOM   667  O OD1 . ASN A 1 103 ? 121.807 124.780 135.536 1.00 125.00 ? 103 ASN H OD1 1 
ATOM   668  N ND2 . ASN A 1 103 ? 119.777 123.835 135.418 1.00 125.00 ? 103 ASN H ND2 1 
ATOM   669  N N   . PHE A 1 104 ? 122.790 121.482 133.998 1.00 120.62 ? 104 PHE H N   1 
ATOM   670  C CA  . PHE A 1 104 ? 123.133 121.203 132.610 1.00 120.62 ? 104 PHE H CA  1 
ATOM   671  C C   . PHE A 1 104 ? 122.770 122.365 131.708 1.00 120.62 ? 104 PHE H C   1 
ATOM   672  O O   . PHE A 1 104 ? 123.575 122.787 130.870 1.00 120.62 ? 104 PHE H O   1 
ATOM   673  C CB  . PHE A 1 104 ? 122.427 119.935 132.149 1.00 120.62 ? 104 PHE H CB  1 
ATOM   674  C CG  . PHE A 1 104 ? 122.719 119.562 130.732 1.00 120.62 ? 104 PHE H CG  1 
ATOM   675  C CD1 . PHE A 1 104 ? 123.924 118.975 130.395 1.00 120.62 ? 104 PHE H CD1 1 
ATOM   676  C CD2 . PHE A 1 104 ? 121.784 119.790 129.734 1.00 120.62 ? 104 PHE H CD2 1 
ATOM   677  C CE1 . PHE A 1 104 ? 124.194 118.627 129.097 1.00 120.62 ? 104 PHE H CE1 1 
ATOM   678  C CE2 . PHE A 1 104 ? 122.053 119.445 128.430 1.00 120.62 ? 104 PHE H CE2 1 
ATOM   679  C CZ  . PHE A 1 104 ? 123.260 118.862 128.115 1.00 120.62 ? 104 PHE H CZ  1 
ATOM   680  N N   . ASP A 1 105 ? 121.553 122.874 131.845 1.00 121.52 ? 105 ASP H N   1 
ATOM   681  C CA  . ASP A 1 105 ? 121.153 124.054 131.101 1.00 121.52 ? 105 ASP H CA  1 
ATOM   682  C C   . ASP A 1 105 ? 121.927 125.258 131.613 1.00 121.52 ? 105 ASP H C   1 
ATOM   683  O O   . ASP A 1 105 ? 122.285 125.327 132.789 1.00 121.52 ? 105 ASP H O   1 
ATOM   684  C CB  . ASP A 1 105 ? 119.654 124.287 131.252 1.00 121.52 ? 105 ASP H CB  1 
ATOM   685  C CG  . ASP A 1 105 ? 119.114 125.278 130.251 1.00 121.52 ? 105 ASP H CG  1 
ATOM   686  O OD1 . ASP A 1 105 ? 119.887 125.777 129.409 1.00 121.52 ? 105 ASP H OD1 1 
ATOM   687  O OD2 . ASP A 1 105 ? 117.901 125.561 130.306 1.00 121.52 ? 105 ASP H OD2 1 
ATOM   688  N N   . SER A 1 106 ? 122.213 126.193 130.717 1.00 116.46 ? 106 SER H N   1 
ATOM   689  C CA  . SER A 1 106 ? 122.872 127.419 131.132 1.00 116.46 ? 106 SER H CA  1 
ATOM   690  C C   . SER A 1 106 ? 121.904 128.275 131.924 1.00 116.46 ? 106 SER H C   1 
ATOM   691  O O   . SER A 1 106 ? 120.790 128.557 131.477 1.00 116.46 ? 106 SER H O   1 
ATOM   692  C CB  . SER A 1 106 ? 123.392 128.187 129.930 1.00 116.46 ? 106 SER H CB  1 
ATOM   693  O OG  . SER A 1 106 ? 123.959 129.422 130.323 1.00 116.46 ? 106 SER H OG  1 
ATOM   694  N N   . SER A 1 107 ? 122.318 128.638 133.126 1.00 122.41 ? 107 SER H N   1 
ATOM   695  C CA  . SER A 1 107 ? 121.530 129.465 134.022 1.00 122.41 ? 107 SER H CA  1 
ATOM   696  C C   . SER A 1 107 ? 122.489 130.081 135.019 1.00 122.41 ? 107 SER H C   1 
ATOM   697  O O   . SER A 1 107 ? 123.693 130.155 134.760 1.00 122.41 ? 107 SER H O   1 
ATOM   698  C CB  . SER A 1 107 ? 120.447 128.656 134.728 1.00 122.41 ? 107 SER H CB  1 
ATOM   699  O OG  . SER A 1 107 ? 119.466 128.197 133.814 1.00 122.41 ? 107 SER H OG  1 
ATOM   700  N N   . PHE A 1 108 ? 121.979 130.559 136.137 1.00 126.91 ? 108 PHE H N   1 
ATOM   701  C CA  . PHE A 1 108 ? 122.859 131.040 137.180 1.00 126.91 ? 108 PHE H CA  1 
ATOM   702  C C   . PHE A 1 108 ? 122.506 130.536 138.566 1.00 126.91 ? 108 PHE H C   1 
ATOM   703  O O   . PHE A 1 108 ? 123.185 130.910 139.525 1.00 126.91 ? 108 PHE H O   1 
ATOM   704  C CB  . PHE A 1 108 ? 122.899 132.569 137.169 1.00 126.91 ? 108 PHE H CB  1 
ATOM   705  C CG  . PHE A 1 108 ? 123.562 133.126 135.953 1.00 126.91 ? 108 PHE H CG  1 
ATOM   706  C CD1 . PHE A 1 108 ? 124.941 133.187 135.871 1.00 126.91 ? 108 PHE H CD1 1 
ATOM   707  C CD2 . PHE A 1 108 ? 122.810 133.559 134.877 1.00 126.91 ? 108 PHE H CD2 1 
ATOM   708  C CE1 . PHE A 1 108 ? 125.554 133.687 134.744 1.00 126.91 ? 108 PHE H CE1 1 
ATOM   709  C CE2 . PHE A 1 108 ? 123.424 134.065 133.751 1.00 126.91 ? 108 PHE H CE2 1 
ATOM   710  C CZ  . PHE A 1 108 ? 124.797 134.127 133.688 1.00 126.91 ? 108 PHE H CZ  1 
ATOM   711  N N   . TYR A 1 109 ? 121.490 129.699 138.707 1.00 128.83 ? 109 TYR H N   1 
ATOM   712  C CA  . TYR A 1 109 ? 121.358 128.950 139.942 1.00 128.83 ? 109 TYR H CA  1 
ATOM   713  C C   . TYR A 1 109 ? 122.293 127.752 139.908 1.00 128.83 ? 109 TYR H C   1 
ATOM   714  O O   . TYR A 1 109 ? 122.797 127.357 138.860 1.00 128.83 ? 109 TYR H O   1 
ATOM   715  C CB  . TYR A 1 109 ? 119.914 128.506 140.168 1.00 128.83 ? 109 TYR H CB  1 
ATOM   716  C CG  . TYR A 1 109 ? 119.361 127.574 139.128 1.00 128.83 ? 109 TYR H CG  1 
ATOM   717  C CD1 . TYR A 1 109 ? 118.733 128.071 138.003 1.00 128.83 ? 109 TYR H CD1 1 
ATOM   718  C CD2 . TYR A 1 109 ? 119.427 126.196 139.290 1.00 128.83 ? 109 TYR H CD2 1 
ATOM   719  C CE1 . TYR A 1 109 ? 118.213 127.232 137.061 1.00 128.83 ? 109 TYR H CE1 1 
ATOM   720  C CE2 . TYR A 1 109 ? 118.923 125.355 138.348 1.00 128.83 ? 109 TYR H CE2 1 
ATOM   721  C CZ  . TYR A 1 109 ? 118.319 125.883 137.235 1.00 128.83 ? 109 TYR H CZ  1 
ATOM   722  O OH  . TYR A 1 109 ? 117.800 125.036 136.286 1.00 128.83 ? 109 TYR H OH  1 
ATOM   723  N N   . PHE A 1 110 ? 122.496 127.148 141.073 1.00 130.29 ? 110 PHE H N   1 
ATOM   724  C CA  . PHE A 1 110 ? 123.401 126.014 141.175 1.00 130.29 ? 110 PHE H CA  1 
ATOM   725  C C   . PHE A 1 110 ? 123.029 125.143 142.364 1.00 130.29 ? 110 PHE H C   1 
ATOM   726  O O   . PHE A 1 110 ? 122.539 125.646 143.374 1.00 130.29 ? 110 PHE H O   1 
ATOM   727  C CB  . PHE A 1 110 ? 124.858 126.481 141.249 1.00 130.29 ? 110 PHE H CB  1 
ATOM   728  C CG  . PHE A 1 110 ? 125.118 127.585 142.204 1.00 130.29 ? 110 PHE H CG  1 
ATOM   729  C CD1 . PHE A 1 110 ? 125.444 127.320 143.512 1.00 130.29 ? 110 PHE H CD1 1 
ATOM   730  C CD2 . PHE A 1 110 ? 125.106 128.897 141.769 1.00 130.29 ? 110 PHE H CD2 1 
ATOM   731  C CE1 . PHE A 1 110 ? 125.721 128.355 144.386 1.00 130.29 ? 110 PHE H CE1 1 
ATOM   732  C CE2 . PHE A 1 110 ? 125.383 129.934 142.626 1.00 130.29 ? 110 PHE H CE2 1 
ATOM   733  C CZ  . PHE A 1 110 ? 125.688 129.655 143.938 1.00 130.29 ? 110 PHE H CZ  1 
ATOM   734  N N   . ASP A 1 111 ? 123.298 123.838 142.238 1.00 129.07 ? 111 ASP H N   1 
ATOM   735  C CA  . ASP A 1 111 ? 122.633 122.818 143.044 1.00 129.07 ? 111 ASP H CA  1 
ATOM   736  C C   . ASP A 1 111 ? 123.542 121.960 143.916 1.00 129.07 ? 111 ASP H C   1 
ATOM   737  O O   . ASP A 1 111 ? 123.176 121.667 145.054 1.00 129.07 ? 111 ASP H O   1 
ATOM   738  C CB  . ASP A 1 111 ? 121.807 121.915 142.124 1.00 129.07 ? 111 ASP H CB  1 
ATOM   739  C CG  . ASP A 1 111 ? 122.627 121.299 141.016 1.00 129.07 ? 111 ASP H CG  1 
ATOM   740  O OD1 . ASP A 1 111 ? 123.821 121.640 140.884 1.00 129.07 ? 111 ASP H OD1 1 
ATOM   741  O OD2 . ASP A 1 111 ? 122.082 120.455 140.277 1.00 129.07 ? 111 ASP H OD2 1 
ATOM   742  N N   . TYR A 1 112 ? 124.699 121.523 143.427 1.00 127.19 ? 112 TYR H N   1 
ATOM   743  C CA  . TYR A 1 112 ? 125.572 120.656 144.207 1.00 127.19 ? 112 TYR H CA  1 
ATOM   744  C C   . TYR A 1 112 ? 126.705 121.456 144.830 1.00 127.19 ? 112 TYR H C   1 
ATOM   745  O O   . TYR A 1 112 ? 127.154 122.465 144.286 1.00 127.19 ? 112 TYR H O   1 
ATOM   746  C CB  . TYR A 1 112 ? 126.134 119.521 143.356 1.00 127.19 ? 112 TYR H CB  1 
ATOM   747  C CG  . TYR A 1 112 ? 125.081 118.531 142.946 1.00 127.19 ? 112 TYR H CG  1 
ATOM   748  C CD1 . TYR A 1 112 ? 124.633 117.556 143.826 1.00 127.19 ? 112 TYR H CD1 1 
ATOM   749  C CD2 . TYR A 1 112 ? 124.516 118.583 141.689 1.00 127.19 ? 112 TYR H CD2 1 
ATOM   750  C CE1 . TYR A 1 112 ? 123.656 116.656 143.454 1.00 127.19 ? 112 TYR H CE1 1 
ATOM   751  C CE2 . TYR A 1 112 ? 123.544 117.688 141.304 1.00 127.19 ? 112 TYR H CE2 1 
ATOM   752  C CZ  . TYR A 1 112 ? 123.117 116.729 142.190 1.00 127.19 ? 112 TYR H CZ  1 
ATOM   753  O OH  . TYR A 1 112 ? 122.145 115.839 141.804 1.00 127.19 ? 112 TYR H OH  1 
ATOM   754  N N   . TRP A 1 113 ? 127.177 120.978 145.977 1.00 126.54 ? 113 TRP H N   1 
ATOM   755  C CA  . TRP A 1 113 ? 128.013 121.773 146.859 1.00 126.54 ? 113 TRP H CA  1 
ATOM   756  C C   . TRP A 1 113 ? 129.146 120.930 147.425 1.00 126.54 ? 113 TRP H C   1 
ATOM   757  O O   . TRP A 1 113 ? 129.123 119.699 147.367 1.00 126.54 ? 113 TRP H O   1 
ATOM   758  C CB  . TRP A 1 113 ? 127.179 122.334 148.004 1.00 126.54 ? 113 TRP H CB  1 
ATOM   759  C CG  . TRP A 1 113 ? 126.194 123.368 147.604 1.00 126.54 ? 113 TRP H CG  1 
ATOM   760  C CD1 . TRP A 1 113 ? 124.949 123.158 147.099 1.00 126.54 ? 113 TRP H CD1 1 
ATOM   761  C CD2 . TRP A 1 113 ? 126.327 124.779 147.764 1.00 126.54 ? 113 TRP H CD2 1 
ATOM   762  N NE1 . TRP A 1 113 ? 124.314 124.356 146.888 1.00 126.54 ? 113 TRP H NE1 1 
ATOM   763  C CE2 . TRP A 1 113 ? 125.140 125.366 147.300 1.00 126.54 ? 113 TRP H CE2 1 
ATOM   764  C CE3 . TRP A 1 113 ? 127.341 125.604 148.246 1.00 126.54 ? 113 TRP H CE3 1 
ATOM   765  C CZ2 . TRP A 1 113 ? 124.942 126.736 147.298 1.00 126.54 ? 113 TRP H CZ2 1 
ATOM   766  C CZ3 . TRP A 1 113 ? 127.147 126.964 148.244 1.00 126.54 ? 113 TRP H CZ3 1 
ATOM   767  C CH2 . TRP A 1 113 ? 125.956 127.520 147.771 1.00 126.54 ? 113 TRP H CH2 1 
ATOM   768  N N   . GLY A 1 114 ? 130.144 121.619 147.989 1.00 131.92 ? 114 GLY H N   1 
ATOM   769  C CA  . GLY A 1 114 ? 131.204 120.969 148.727 1.00 131.92 ? 114 GLY H CA  1 
ATOM   770  C C   . GLY A 1 114 ? 131.312 121.562 150.121 1.00 131.92 ? 114 GLY H C   1 
ATOM   771  O O   . GLY A 1 114 ? 130.689 122.575 150.437 1.00 131.92 ? 114 GLY H O   1 
ATOM   772  N N   . ARG A 1 115 ? 132.116 120.907 150.955 1.00 135.13 ? 115 ARG H N   1 
ATOM   773  C CA  . ARG A 1 115 ? 132.234 121.343 152.340 1.00 135.13 ? 115 ARG H CA  1 
ATOM   774  C C   . ARG A 1 115 ? 133.117 122.575 152.488 1.00 135.13 ? 115 ARG H C   1 
ATOM   775  O O   . ARG A 1 115 ? 132.912 123.368 153.412 1.00 135.13 ? 115 ARG H O   1 
ATOM   776  C CB  . ARG A 1 115 ? 132.771 120.201 153.197 1.00 135.13 ? 115 ARG H CB  1 
ATOM   777  C CG  . ARG A 1 115 ? 131.834 119.018 153.276 1.00 135.13 ? 115 ARG H CG  1 
ATOM   778  C CD  . ARG A 1 115 ? 130.600 119.384 154.067 1.00 135.13 ? 115 ARG H CD  1 
ATOM   779  N NE  . ARG A 1 115 ? 129.718 118.244 154.283 1.00 135.13 ? 115 ARG H NE  1 
ATOM   780  C CZ  . ARG A 1 115 ? 128.735 117.900 153.459 1.00 135.13 ? 115 ARG H CZ  1 
ATOM   781  N NH1 . ARG A 1 115 ? 128.516 118.604 152.360 1.00 135.13 ? 115 ARG H NH1 1 
ATOM   782  N NH2 . ARG A 1 115 ? 127.974 116.850 153.731 1.00 135.13 ? 115 ARG H NH2 1 
ATOM   783  N N   . ALA B 2 2   ? 131.946 151.745 117.800 1.00 115.07 ? 1   ALA c N   1 
ATOM   784  C CA  . ALA B 2 2   ? 131.781 152.926 116.964 1.00 115.07 ? 1   ALA c CA  1 
ATOM   785  C C   . ALA B 2 2   ? 133.069 153.734 116.928 1.00 115.07 ? 1   ALA c C   1 
ATOM   786  O O   . ALA B 2 2   ? 133.876 153.591 116.012 1.00 115.07 ? 1   ALA c O   1 
ATOM   787  C CB  . ALA B 2 2   ? 130.634 153.777 117.470 1.00 115.07 ? 1   ALA c CB  1 
ATOM   788  N N   . LYS B 2 3   ? 133.246 154.593 117.926 1.00 119.23 ? 2   LYS c N   1 
ATOM   789  C CA  . LYS B 2 3   ? 134.481 155.355 118.078 1.00 119.23 ? 2   LYS c CA  1 
ATOM   790  C C   . LYS B 2 3   ? 135.576 154.387 118.492 1.00 119.23 ? 2   LYS c C   1 
ATOM   791  O O   . LYS B 2 3   ? 135.628 153.946 119.641 1.00 119.23 ? 2   LYS c O   1 
ATOM   792  C CB  . LYS B 2 3   ? 134.300 156.461 119.110 1.00 119.23 ? 2   LYS c CB  1 
ATOM   793  C CG  . LYS B 2 3   ? 135.511 157.351 119.289 1.00 119.23 ? 2   LYS c CG  1 
ATOM   794  C CD  . LYS B 2 3   ? 135.752 158.195 118.055 1.00 119.23 ? 2   LYS c CD  1 
ATOM   795  C CE  . LYS B 2 3   ? 136.953 159.105 118.237 1.00 119.23 ? 2   LYS c CE  1 
ATOM   796  N NZ  . LYS B 2 3   ? 136.712 160.134 119.283 1.00 119.23 ? 2   LYS c NZ  1 
ATOM   797  N N   . LEU B 2 4   ? 136.445 154.037 117.551 1.00 113.44 ? 3   LEU c N   1 
ATOM   798  C CA  . LEU B 2 4   ? 137.449 153.015 117.799 1.00 113.44 ? 3   LEU c CA  1 
ATOM   799  C C   . LEU B 2 4   ? 138.566 153.567 118.674 1.00 113.44 ? 3   LEU c C   1 
ATOM   800  O O   . LEU B 2 4   ? 138.986 154.717 118.525 1.00 113.44 ? 3   LEU c O   1 
ATOM   801  C CB  . LEU B 2 4   ? 138.008 152.473 116.482 1.00 113.44 ? 3   LEU c CB  1 
ATOM   802  C CG  . LEU B 2 4   ? 139.015 153.225 115.609 1.00 113.44 ? 3   LEU c CG  1 
ATOM   803  C CD1 . LEU B 2 4   ? 139.609 152.256 114.614 1.00 113.44 ? 3   LEU c CD1 1 
ATOM   804  C CD2 . LEU B 2 4   ? 138.400 154.404 114.883 1.00 113.44 ? 3   LEU c CD2 1 
ATOM   805  N N   . GLU B 2 5   ? 139.017 152.748 119.620 1.00 116.27 ? 4   GLU c N   1 
ATOM   806  C CA  . GLU B 2 5   ? 140.013 153.178 120.592 1.00 116.27 ? 4   GLU c CA  1 
ATOM   807  C C   . GLU B 2 5   ? 141.123 152.150 120.726 1.00 116.27 ? 4   GLU c C   1 
ATOM   808  O O   . GLU B 2 5   ? 141.178 151.183 119.962 1.00 116.27 ? 4   GLU c O   1 
ATOM   809  C CB  . GLU B 2 5   ? 139.369 153.421 121.955 1.00 116.27 ? 4   GLU c CB  1 
ATOM   810  C CG  . GLU B 2 5   ? 138.456 154.628 122.017 1.00 116.27 ? 4   GLU c CG  1 
ATOM   811  C CD  . GLU B 2 5   ? 137.820 154.801 123.381 1.00 116.27 ? 4   GLU c CD  1 
ATOM   812  O OE1 . GLU B 2 5   ? 137.986 153.902 124.232 1.00 116.27 ? 4   GLU c OE1 1 
ATOM   813  O OE2 . GLU B 2 5   ? 137.157 155.835 123.603 1.00 116.27 ? 4   GLU c OE2 1 
ATOM   814  N N   . THR B 2 6   ? 142.004 152.345 121.704 1.00 106.86 ? 5   THR c N   1 
ATOM   815  C CA  . THR B 2 6   ? 143.124 151.438 121.905 1.00 106.86 ? 5   THR c CA  1 
ATOM   816  C C   . THR B 2 6   ? 142.645 150.137 122.526 1.00 106.86 ? 5   THR c C   1 
ATOM   817  O O   . THR B 2 6   ? 142.582 150.011 123.752 1.00 106.86 ? 5   THR c O   1 
ATOM   818  C CB  . THR B 2 6   ? 144.187 152.078 122.793 1.00 106.86 ? 5   THR c CB  1 
ATOM   819  O OG1 . THR B 2 6   ? 143.639 152.305 124.095 1.00 106.86 ? 5   THR c OG1 1 
ATOM   820  C CG2 . THR B 2 6   ? 144.630 153.402 122.211 1.00 106.86 ? 5   THR c CG2 1 
ATOM   821  N N   . VAL B 2 7   ? 142.301 149.166 121.685 1.00 103.33 ? 6   VAL c N   1 
ATOM   822  C CA  . VAL B 2 7   ? 141.812 147.890 122.179 1.00 103.33 ? 6   VAL c CA  1 
ATOM   823  C C   . VAL B 2 7   ? 142.977 147.077 122.719 1.00 103.33 ? 6   VAL c C   1 
ATOM   824  O O   . VAL B 2 7   ? 143.975 146.849 122.024 1.00 103.33 ? 6   VAL c O   1 
ATOM   825  C CB  . VAL B 2 7   ? 141.078 147.133 121.067 1.00 103.33 ? 6   VAL c CB  1 
ATOM   826  C CG1 . VAL B 2 7   ? 140.646 145.769 121.556 1.00 103.33 ? 6   VAL c CG1 1 
ATOM   827  C CG2 . VAL B 2 7   ? 139.888 147.934 120.598 1.00 103.33 ? 6   VAL c CG2 1 
ATOM   828  N N   . THR B 2 8   ? 142.861 146.643 123.967 1.00 103.81 ? 7   THR c N   1 
ATOM   829  C CA  . THR B 2 8   ? 143.864 145.799 124.594 1.00 103.81 ? 7   THR c CA  1 
ATOM   830  C C   . THR B 2 8   ? 143.249 144.443 124.882 1.00 103.81 ? 7   THR c C   1 
ATOM   831  O O   . THR B 2 8   ? 142.175 144.361 125.482 1.00 103.81 ? 7   THR c O   1 
ATOM   832  C CB  . THR B 2 8   ? 144.377 146.410 125.888 1.00 103.81 ? 7   THR c CB  1 
ATOM   833  O OG1 . THR B 2 8   ? 143.309 146.458 126.838 1.00 103.81 ? 7   THR c OG1 1 
ATOM   834  C CG2 . THR B 2 8   ? 144.872 147.817 125.639 1.00 103.81 ? 7   THR c CG2 1 
ATOM   835  N N   . LEU B 2 9   ? 143.933 143.391 124.463 1.00 105.11 ? 8   LEU c N   1 
ATOM   836  C CA  . LEU B 2 9   ? 143.496 142.032 124.732 1.00 105.11 ? 8   LEU c CA  1 
ATOM   837  C C   . LEU B 2 9   ? 144.035 141.613 126.095 1.00 105.11 ? 8   LEU c C   1 
ATOM   838  O O   . LEU B 2 9   ? 144.558 142.427 126.858 1.00 105.11 ? 8   LEU c O   1 
ATOM   839  C CB  . LEU B 2 9   ? 143.954 141.093 123.621 1.00 105.11 ? 8   LEU c CB  1 
ATOM   840  C CG  . LEU B 2 9   ? 143.099 140.969 122.358 1.00 105.11 ? 8   LEU c CG  1 
ATOM   841  C CD1 . LEU B 2 9   ? 141.698 140.541 122.731 1.00 105.11 ? 8   LEU c CD1 1 
ATOM   842  C CD2 . LEU B 2 9   ? 143.072 142.219 121.494 1.00 105.11 ? 8   LEU c CD2 1 
ATOM   843  N N   . GLY B 2 10  ? 143.921 140.332 126.421 1.00 109.46 ? 9   GLY c N   1 
ATOM   844  C CA  . GLY B 2 10  ? 144.464 139.861 127.676 1.00 109.46 ? 9   GLY c CA  1 
ATOM   845  C C   . GLY B 2 10  ? 144.534 138.357 127.798 1.00 109.46 ? 9   GLY c C   1 
ATOM   846  O O   . GLY B 2 10  ? 143.547 137.667 127.524 1.00 109.46 ? 9   GLY c O   1 
ATOM   847  N N   . ASN B 2 11  ? 145.707 137.859 128.204 1.00 113.75 ? 10  ASN c N   1 
ATOM   848  C CA  . ASN B 2 11  ? 145.960 136.462 128.565 1.00 113.75 ? 10  ASN c CA  1 
ATOM   849  C C   . ASN B 2 11  ? 145.658 135.520 127.396 1.00 113.75 ? 10  ASN c C   1 
ATOM   850  O O   . ASN B 2 11  ? 144.755 134.686 127.445 1.00 113.75 ? 10  ASN c O   1 
ATOM   851  C CB  . ASN B 2 11  ? 145.153 136.079 129.808 1.00 113.75 ? 10  ASN c CB  1 
ATOM   852  C CG  . ASN B 2 11  ? 145.490 136.941 130.990 1.00 113.75 ? 10  ASN c CG  1 
ATOM   853  O OD1 . ASN B 2 11  ? 144.671 137.736 131.441 1.00 113.75 ? 10  ASN c OD1 1 
ATOM   854  N ND2 . ASN B 2 11  ? 146.705 136.800 131.499 1.00 113.75 ? 10  ASN c ND2 1 
ATOM   855  N N   . ILE B 2 12  ? 146.436 135.686 126.331 1.00 112.19 ? 11  ILE c N   1 
ATOM   856  C CA  . ILE B 2 12  ? 146.158 135.004 125.077 1.00 112.19 ? 11  ILE c CA  1 
ATOM   857  C C   . ILE B 2 12  ? 147.382 134.240 124.594 1.00 112.19 ? 11  ILE c C   1 
ATOM   858  O O   . ILE B 2 12  ? 148.509 134.740 124.655 1.00 112.19 ? 11  ILE c O   1 
ATOM   859  C CB  . ILE B 2 12  ? 145.634 135.981 124.007 1.00 112.19 ? 11  ILE c CB  1 
ATOM   860  C CG1 . ILE B 2 12  ? 146.474 137.248 123.910 1.00 112.19 ? 11  ILE c CG1 1 
ATOM   861  C CG2 . ILE B 2 12  ? 144.214 136.359 124.307 1.00 112.19 ? 11  ILE c CG2 1 
ATOM   862  C CD1 . ILE B 2 12  ? 147.505 137.247 122.822 1.00 112.19 ? 11  ILE c CD1 1 
ATOM   863  N N   . GLY B 2 13  ? 147.149 133.004 124.169 1.00 110.39 ? 12  GLY c N   1 
ATOM   864  C CA  . GLY B 2 13  ? 148.071 132.184 123.410 1.00 110.39 ? 12  GLY c CA  1 
ATOM   865  C C   . GLY B 2 13  ? 148.791 131.147 124.243 1.00 110.39 ? 12  GLY c C   1 
ATOM   866  O O   . GLY B 2 13  ? 149.836 131.428 124.833 1.00 110.39 ? 12  GLY c O   1 
ATOM   867  N N   . LYS B 2 14  ? 148.202 129.948 124.316 1.00 111.55 ? 13  LYS c N   1 
ATOM   868  C CA  . LYS B 2 14  ? 148.773 128.683 124.785 1.00 111.55 ? 13  LYS c CA  1 
ATOM   869  C C   . LYS B 2 14  ? 149.079 128.646 126.288 1.00 111.55 ? 13  LYS c C   1 
ATOM   870  O O   . LYS B 2 14  ? 149.135 127.567 126.887 1.00 111.55 ? 13  LYS c O   1 
ATOM   871  C CB  . LYS B 2 14  ? 150.023 128.363 123.944 1.00 111.55 ? 13  LYS c CB  1 
ATOM   872  C CG  . LYS B 2 14  ? 150.742 127.051 124.227 1.00 111.55 ? 13  LYS c CG  1 
ATOM   873  C CD  . LYS B 2 14  ? 149.840 125.859 124.017 1.00 111.55 ? 13  LYS c CD  1 
ATOM   874  C CE  . LYS B 2 14  ? 149.502 125.685 122.557 1.00 111.55 ? 13  LYS c CE  1 
ATOM   875  N NZ  . LYS B 2 14  ? 150.704 125.289 121.777 1.00 111.55 ? 13  LYS c NZ  1 
ATOM   876  N N   . ASP B 2 15  ? 149.165 129.798 126.947 1.00 118.31 ? 14  ASP c N   1 
ATOM   877  C CA  . ASP B 2 15  ? 149.343 129.808 128.390 1.00 118.31 ? 14  ASP c CA  1 
ATOM   878  C C   . ASP B 2 15  ? 148.576 130.904 129.104 1.00 118.31 ? 14  ASP c C   1 
ATOM   879  O O   . ASP B 2 15  ? 148.480 130.855 130.332 1.00 118.31 ? 14  ASP c O   1 
ATOM   880  C CB  . ASP B 2 15  ? 150.836 129.899 128.746 1.00 118.31 ? 14  ASP c CB  1 
ATOM   881  C CG  . ASP B 2 15  ? 151.525 131.119 128.153 1.00 118.31 ? 14  ASP c CG  1 
ATOM   882  O OD1 . ASP B 2 15  ? 150.887 131.916 127.438 1.00 118.31 ? 14  ASP c OD1 1 
ATOM   883  O OD2 . ASP B 2 15  ? 152.739 131.276 128.398 1.00 118.31 ? 14  ASP c OD2 1 
ATOM   884  N N   . GLY B 2 16  ? 148.044 131.893 128.395 1.00 117.06 ? 15  GLY c N   1 
ATOM   885  C CA  . GLY B 2 16  ? 147.437 133.016 129.068 1.00 117.06 ? 15  GLY c CA  1 
ATOM   886  C C   . GLY B 2 16  ? 148.424 133.980 129.678 1.00 117.06 ? 15  GLY c C   1 
ATOM   887  O O   . GLY B 2 16  ? 148.066 134.718 130.596 1.00 117.06 ? 15  GLY c O   1 
ATOM   888  N N   . LYS B 2 17  ? 149.663 133.995 129.199 1.00 119.20 ? 16  LYS c N   1 
ATOM   889  C CA  . LYS B 2 17  ? 150.687 134.868 129.747 1.00 119.20 ? 16  LYS c CA  1 
ATOM   890  C C   . LYS B 2 17  ? 151.092 135.988 128.809 1.00 119.20 ? 16  LYS c C   1 
ATOM   891  O O   . LYS B 2 17  ? 151.994 136.758 129.146 1.00 119.20 ? 16  LYS c O   1 
ATOM   892  C CB  . LYS B 2 17  ? 151.935 134.067 130.112 1.00 119.20 ? 16  LYS c CB  1 
ATOM   893  C CG  . LYS B 2 17  ? 151.778 133.146 131.287 1.00 119.20 ? 16  LYS c CG  1 
ATOM   894  C CD  . LYS B 2 17  ? 153.111 132.499 131.580 1.00 119.20 ? 16  LYS c CD  1 
ATOM   895  C CE  . LYS B 2 17  ? 153.024 131.559 132.747 1.00 119.20 ? 16  LYS c CE  1 
ATOM   896  N NZ  . LYS B 2 17  ? 154.349 130.944 133.027 1.00 119.20 ? 16  LYS c NZ  1 
ATOM   897  N N   . GLN B 2 18  ? 150.484 136.095 127.640 1.00 115.80 ? 17  GLN c N   1 
ATOM   898  C CA  . GLN B 2 18  ? 150.835 137.137 126.694 1.00 115.80 ? 17  GLN c CA  1 
ATOM   899  C C   . GLN B 2 18  ? 149.668 138.097 126.564 1.00 115.80 ? 17  GLN c C   1 
ATOM   900  O O   . GLN B 2 18  ? 148.520 137.668 126.429 1.00 115.80 ? 17  GLN c O   1 
ATOM   901  C CB  . GLN B 2 18  ? 151.194 136.547 125.335 1.00 115.80 ? 17  GLN c CB  1 
ATOM   902  C CG  . GLN B 2 18  ? 152.435 135.693 125.360 1.00 115.80 ? 17  GLN c CG  1 
ATOM   903  C CD  . GLN B 2 18  ? 152.760 135.116 124.006 1.00 115.80 ? 17  GLN c CD  1 
ATOM   904  O OE1 . GLN B 2 18  ? 152.024 135.319 123.043 1.00 115.80 ? 17  GLN c OE1 1 
ATOM   905  N NE2 . GLN B 2 18  ? 153.862 134.387 123.923 1.00 115.80 ? 17  GLN c NE2 1 
ATOM   906  N N   . THR B 2 19  ? 149.959 139.384 126.640 1.00 112.28 ? 18  THR c N   1 
ATOM   907  C CA  . THR B 2 19  ? 148.975 140.419 126.394 1.00 112.28 ? 18  THR c CA  1 
ATOM   908  C C   . THR B 2 19  ? 149.263 141.069 125.052 1.00 112.28 ? 18  THR c C   1 
ATOM   909  O O   . THR B 2 19  ? 150.272 140.792 124.401 1.00 112.28 ? 18  THR c O   1 
ATOM   910  C CB  . THR B 2 19  ? 148.978 141.460 127.508 1.00 112.28 ? 18  THR c CB  1 
ATOM   911  O OG1 . THR B 2 19  ? 147.884 142.361 127.314 1.00 112.28 ? 18  THR c OG1 1 
ATOM   912  C CG2 . THR B 2 19  ? 150.270 142.242 127.485 1.00 112.28 ? 18  THR c CG2 1 
ATOM   913  N N   . LEU B 2 20  ? 148.367 141.955 124.644 1.00 103.88 ? 19  LEU c N   1 
ATOM   914  C CA  . LEU B 2 20  ? 148.496 142.591 123.348 1.00 103.88 ? 19  LEU c CA  1 
ATOM   915  C C   . LEU B 2 20  ? 147.771 143.921 123.396 1.00 103.88 ? 19  LEU c C   1 
ATOM   916  O O   . LEU B 2 20  ? 146.682 144.014 123.959 1.00 103.88 ? 19  LEU c O   1 
ATOM   917  C CB  . LEU B 2 20  ? 147.919 141.701 122.247 1.00 103.88 ? 19  LEU c CB  1 
ATOM   918  C CG  . LEU B 2 20  ? 148.090 142.224 120.831 1.00 103.88 ? 19  LEU c CG  1 
ATOM   919  C CD1 . LEU B 2 20  ? 149.559 142.366 120.533 1.00 103.88 ? 19  LEU c CD1 1 
ATOM   920  C CD2 . LEU B 2 20  ? 147.444 141.277 119.861 1.00 103.88 ? 19  LEU c CD2 1 
ATOM   921  N N   . VAL B 2 21  ? 148.386 144.950 122.830 1.00 99.53  ? 20  VAL c N   1 
ATOM   922  C CA  . VAL B 2 21  ? 147.732 146.238 122.694 1.00 99.53  ? 20  VAL c CA  1 
ATOM   923  C C   . VAL B 2 21  ? 147.607 146.547 121.214 1.00 99.53  ? 20  VAL c C   1 
ATOM   924  O O   . VAL B 2 21  ? 148.373 146.057 120.384 1.00 99.53  ? 20  VAL c O   1 
ATOM   925  C CB  . VAL B 2 21  ? 148.485 147.359 123.428 1.00 99.53  ? 20  VAL c CB  1 
ATOM   926  C CG1 . VAL B 2 21  ? 148.492 147.080 124.902 1.00 99.53  ? 20  VAL c CG1 1 
ATOM   927  C CG2 . VAL B 2 21  ? 149.903 147.464 122.920 1.00 99.53  ? 20  VAL c CG2 1 
ATOM   928  N N   . LEU B 2 22  ? 146.607 147.350 120.882 1.00 99.19  ? 21  LEU c N   1 
ATOM   929  C CA  . LEU B 2 22  ? 146.415 147.784 119.514 1.00 99.19  ? 21  LEU c CA  1 
ATOM   930  C C   . LEU B 2 22  ? 146.209 149.287 119.489 1.00 99.19  ? 21  LEU c C   1 
ATOM   931  O O   . LEU B 2 22  ? 145.730 149.889 120.449 1.00 99.19  ? 21  LEU c O   1 
ATOM   932  C CB  . LEU B 2 22  ? 145.223 147.083 118.864 1.00 99.19  ? 21  LEU c CB  1 
ATOM   933  C CG  . LEU B 2 22  ? 145.394 145.586 118.640 1.00 99.19  ? 21  LEU c CG  1 
ATOM   934  C CD1 . LEU B 2 22  ? 144.119 144.980 118.110 1.00 99.19  ? 21  LEU c CD1 1 
ATOM   935  C CD2 . LEU B 2 22  ? 146.534 145.347 117.683 1.00 99.19  ? 21  LEU c CD2 1 
ATOM   936  N N   . ASN B 2 23  ? 146.584 149.887 118.371 1.00 98.08  ? 22  ASN c N   1 
ATOM   937  C CA  . ASN B 2 23  ? 146.350 151.292 118.151 1.00 98.08  ? 22  ASN c CA  1 
ATOM   938  C C   . ASN B 2 23  ? 145.622 151.449 116.826 1.00 98.08  ? 22  ASN c C   1 
ATOM   939  O O   . ASN B 2 23  ? 145.866 150.674 115.892 1.00 98.08  ? 22  ASN c O   1 
ATOM   940  C CB  . ASN B 2 23  ? 147.667 152.070 118.129 1.00 98.08  ? 22  ASN c CB  1 
ATOM   941  C CG  . ASN B 2 23  ? 148.419 151.959 119.430 1.00 98.08  ? 22  ASN c CG  1 
ATOM   942  O OD1 . ASN B 2 23  ? 149.530 151.437 119.475 1.00 98.08  ? 22  ASN c OD1 1 
ATOM   943  N ND2 . ASN B 2 23  ? 147.809 152.433 120.505 1.00 98.08  ? 22  ASN c ND2 1 
ATOM   944  N N   . PRO B 2 24  ? 144.711 152.409 116.727 1.00 98.19  ? 23  PRO c N   1 
ATOM   945  C CA  . PRO B 2 24  ? 144.011 152.626 115.463 1.00 98.19  ? 23  PRO c CA  1 
ATOM   946  C C   . PRO B 2 24  ? 144.930 153.226 114.423 1.00 98.19  ? 23  PRO c C   1 
ATOM   947  O O   . PRO B 2 24  ? 145.866 153.961 114.735 1.00 98.19  ? 23  PRO c O   1 
ATOM   948  C CB  . PRO B 2 24  ? 142.897 153.601 115.842 1.00 98.19  ? 23  PRO c CB  1 
ATOM   949  C CG  . PRO B 2 24  ? 143.422 154.312 117.022 1.00 98.19  ? 23  PRO c CG  1 
ATOM   950  C CD  . PRO B 2 24  ? 144.226 153.310 117.781 1.00 98.19  ? 23  PRO c CD  1 
ATOM   951  N N   . ARG B 2 25  ? 144.661 152.894 113.170 1.00 95.33  ? 24  ARG c N   1 
ATOM   952  C CA  . ARG B 2 25  ? 145.449 153.409 112.065 1.00 95.33  ? 24  ARG c CA  1 
ATOM   953  C C   . ARG B 2 25  ? 144.501 153.885 110.969 1.00 95.33  ? 24  ARG c C   1 
ATOM   954  O O   . ARG B 2 25  ? 144.645 153.565 109.789 1.00 95.33  ? 24  ARG c O   1 
ATOM   955  C CB  . ARG B 2 25  ? 146.440 152.351 111.588 1.00 95.33  ? 24  ARG c CB  1 
ATOM   956  C CG  . ARG B 2 25  ? 147.600 152.887 110.770 1.00 95.33  ? 24  ARG c CG  1 
ATOM   957  C CD  . ARG B 2 25  ? 148.573 151.785 110.421 1.00 95.33  ? 24  ARG c CD  1 
ATOM   958  N NE  . ARG B 2 25  ? 149.203 151.239 111.616 1.00 95.33  ? 24  ARG c NE  1 
ATOM   959  C CZ  . ARG B 2 25  ? 150.275 151.761 112.198 1.00 95.33  ? 24  ARG c CZ  1 
ATOM   960  N NH1 . ARG B 2 25  ? 150.848 152.844 111.698 1.00 95.33  ? 24  ARG c NH1 1 
ATOM   961  N NH2 . ARG B 2 25  ? 150.774 151.196 113.285 1.00 95.33  ? 24  ARG c NH2 1 
ATOM   962  N N   . GLY B 2 26  ? 143.486 154.637 111.374 1.00 101.35 ? 25  GLY c N   1 
ATOM   963  C CA  . GLY B 2 26  ? 142.622 155.324 110.435 1.00 101.35 ? 25  GLY c CA  1 
ATOM   964  C C   . GLY B 2 26  ? 141.671 154.402 109.695 1.00 101.35 ? 25  GLY c C   1 
ATOM   965  O O   . GLY B 2 26  ? 141.671 153.183 109.845 1.00 101.35 ? 25  GLY c O   1 
ATOM   966  N N   . VAL B 2 27  ? 140.841 155.026 108.867 1.00 107.71 ? 26  VAL c N   1 
ATOM   967  C CA  . VAL B 2 27  ? 139.873 154.328 108.037 1.00 107.71 ? 26  VAL c CA  1 
ATOM   968  C C   . VAL B 2 27  ? 140.231 154.601 106.589 1.00 107.71 ? 26  VAL c C   1 
ATOM   969  O O   . VAL B 2 27  ? 140.353 155.763 106.187 1.00 107.71 ? 26  VAL c O   1 
ATOM   970  C CB  . VAL B 2 27  ? 138.438 154.781 108.336 1.00 107.71 ? 26  VAL c CB  1 
ATOM   971  C CG1 . VAL B 2 27  ? 137.468 154.116 107.387 1.00 107.71 ? 26  VAL c CG1 1 
ATOM   972  C CG2 . VAL B 2 27  ? 138.080 154.470 109.769 1.00 107.71 ? 26  VAL c CG2 1 
ATOM   973  N N   . ASN B 2 28  ? 140.418 153.543 105.821 1.00 112.39 ? 27  ASN c N   1 
ATOM   974  C CA  . ASN B 2 28  ? 140.635 153.667 104.388 1.00 112.39 ? 27  ASN c CA  1 
ATOM   975  C C   . ASN B 2 28  ? 139.359 154.181 103.737 1.00 112.39 ? 27  ASN c C   1 
ATOM   976  O O   . ASN B 2 28  ? 138.335 153.491 103.779 1.00 112.39 ? 27  ASN c O   1 
ATOM   977  C CB  . ASN B 2 28  ? 141.026 152.310 103.813 1.00 112.39 ? 27  ASN c CB  1 
ATOM   978  C CG  . ASN B 2 28  ? 141.520 152.387 102.382 1.00 112.39 ? 27  ASN c CG  1 
ATOM   979  O OD1 . ASN B 2 28  ? 141.606 153.459 101.788 1.00 112.39 ? 27  ASN c OD1 1 
ATOM   980  N ND2 . ASN B 2 28  ? 141.841 151.232 101.816 1.00 112.39 ? 27  ASN c ND2 1 
ATOM   981  N N   . PRO B 2 29  ? 139.366 155.371 103.129 1.00 112.55 ? 28  PRO c N   1 
ATOM   982  C CA  . PRO B 2 29  ? 138.124 155.914 102.565 1.00 112.55 ? 28  PRO c CA  1 
ATOM   983  C C   . PRO B 2 29  ? 137.698 155.258 101.268 1.00 112.55 ? 28  PRO c C   1 
ATOM   984  O O   . PRO B 2 29  ? 136.558 155.470 100.839 1.00 112.55 ? 28  PRO c O   1 
ATOM   985  C CB  . PRO B 2 29  ? 138.463 157.390 102.342 1.00 112.55 ? 28  PRO c CB  1 
ATOM   986  C CG  . PRO B 2 29  ? 139.922 157.387 102.107 1.00 112.55 ? 28  PRO c CG  1 
ATOM   987  C CD  . PRO B 2 29  ? 140.492 156.305 102.976 1.00 112.55 ? 28  PRO c CD  1 
ATOM   988  N N   . THR B 2 30  ? 138.566 154.474 100.631 1.00 117.45 ? 29  THR c N   1 
ATOM   989  C CA  . THR B 2 30  ? 138.206 153.864 99.358  1.00 117.45 ? 29  THR c CA  1 
ATOM   990  C C   . THR B 2 30  ? 137.236 152.707 99.540  1.00 117.45 ? 29  THR c C   1 
ATOM   991  O O   . THR B 2 30  ? 136.390 152.468 98.672  1.00 117.45 ? 29  THR c O   1 
ATOM   992  C CB  . THR B 2 30  ? 139.460 153.380 98.639  1.00 117.45 ? 29  THR c CB  1 
ATOM   993  O OG1 . THR B 2 30  ? 140.092 152.366 99.427  1.00 117.45 ? 29  THR c OG1 1 
ATOM   994  C CG2 . THR B 2 30  ? 140.428 154.529 98.444  1.00 117.45 ? 29  THR c CG2 1 
ATOM   995  N N   . ASN B 2 31  ? 137.340 151.979 100.647 1.00 108.10 ? 30  ASN c N   1 
ATOM   996  C CA  . ASN B 2 31  ? 136.503 150.810 100.858 1.00 108.10 ? 30  ASN c CA  1 
ATOM   997  C C   . ASN B 2 31  ? 135.928 150.691 102.261 1.00 108.10 ? 30  ASN c C   1 
ATOM   998  O O   . ASN B 2 31  ? 135.160 149.759 102.510 1.00 108.10 ? 30  ASN c O   1 
ATOM   999  C CB  . ASN B 2 31  ? 137.292 149.540 100.514 1.00 108.10 ? 30  ASN c CB  1 
ATOM   1000 C CG  . ASN B 2 31  ? 138.620 149.458 101.242 1.00 108.10 ? 30  ASN c CG  1 
ATOM   1001 O OD1 . ASN B 2 31  ? 138.943 150.296 102.083 1.00 108.10 ? 30  ASN c OD1 1 
ATOM   1002 N ND2 . ASN B 2 31  ? 139.404 148.438 100.916 1.00 108.10 ? 30  ASN c ND2 1 
ATOM   1003 N N   . GLY B 2 32  ? 136.271 151.588 103.178 1.00 102.83 ? 31  GLY c N   1 
ATOM   1004 C CA  . GLY B 2 32  ? 135.713 151.551 104.514 1.00 102.83 ? 31  GLY c CA  1 
ATOM   1005 C C   . GLY B 2 32  ? 136.222 150.402 105.354 1.00 102.83 ? 31  GLY c C   1 
ATOM   1006 O O   . GLY B 2 32  ? 135.433 149.634 105.906 1.00 102.83 ? 31  GLY c O   1 
ATOM   1007 N N   . VAL B 2 33  ? 137.538 150.268 105.458 1.00 98.87  ? 32  VAL c N   1 
ATOM   1008 C CA  . VAL B 2 33  ? 138.161 149.190 106.210 1.00 98.87  ? 32  VAL c CA  1 
ATOM   1009 C C   . VAL B 2 33  ? 138.984 149.821 107.318 1.00 98.87  ? 32  VAL c C   1 
ATOM   1010 O O   . VAL B 2 33  ? 140.006 150.463 107.050 1.00 98.87  ? 32  VAL c O   1 
ATOM   1011 C CB  . VAL B 2 33  ? 139.034 148.301 105.319 1.00 98.87  ? 32  VAL c CB  1 
ATOM   1012 C CG1 . VAL B 2 33  ? 139.734 147.252 106.151 1.00 98.87  ? 32  VAL c CG1 1 
ATOM   1013 C CG2 . VAL B 2 33  ? 138.194 147.656 104.241 1.00 98.87  ? 32  VAL c CG2 1 
ATOM   1014 N N   . ALA B 2 34  ? 138.546 149.649 108.556 1.00 93.93  ? 33  ALA c N   1 
ATOM   1015 C CA  . ALA B 2 34  ? 139.316 150.145 109.681 1.00 93.93  ? 33  ALA c CA  1 
ATOM   1016 C C   . ALA B 2 34  ? 140.457 149.192 109.995 1.00 93.93  ? 33  ALA c C   1 
ATOM   1017 O O   . ALA B 2 34  ? 140.371 147.987 109.750 1.00 93.93  ? 33  ALA c O   1 
ATOM   1018 C CB  . ALA B 2 34  ? 138.434 150.311 110.911 1.00 93.93  ? 33  ALA c CB  1 
ATOM   1019 N N   . SER B 2 35  ? 141.523 149.742 110.564 1.00 97.26  ? 34  SER c N   1 
ATOM   1020 C CA  . SER B 2 35  ? 142.728 148.981 110.838 1.00 97.26  ? 34  SER c CA  1 
ATOM   1021 C C   . SER B 2 35  ? 143.192 149.217 112.265 1.00 97.26  ? 34  SER c C   1 
ATOM   1022 O O   . SER B 2 35  ? 142.918 150.257 112.865 1.00 97.26  ? 34  SER c O   1 
ATOM   1023 C CB  . SER B 2 35  ? 143.844 149.352 109.871 1.00 97.26  ? 34  SER c CB  1 
ATOM   1024 O OG  . SER B 2 35  ? 143.481 149.025 108.544 1.00 97.26  ? 34  SER c OG  1 
ATOM   1025 N N   . LEU B 2 36  ? 143.896 148.229 112.798 1.00 96.40  ? 35  LEU c N   1 
ATOM   1026 C CA  . LEU B 2 36  ? 144.481 148.268 114.125 1.00 96.40  ? 35  LEU c CA  1 
ATOM   1027 C C   . LEU B 2 36  ? 145.835 147.592 114.033 1.00 96.40  ? 35  LEU c C   1 
ATOM   1028 O O   . LEU B 2 36  ? 145.996 146.626 113.282 1.00 96.40  ? 35  LEU c O   1 
ATOM   1029 C CB  . LEU B 2 36  ? 143.615 147.536 115.149 1.00 96.40  ? 35  LEU c CB  1 
ATOM   1030 C CG  . LEU B 2 36  ? 142.209 148.053 115.426 1.00 96.40  ? 35  LEU c CG  1 
ATOM   1031 C CD1 . LEU B 2 36  ? 141.472 147.100 116.333 1.00 96.40  ? 35  LEU c CD1 1 
ATOM   1032 C CD2 . LEU B 2 36  ? 142.275 149.411 116.051 1.00 96.40  ? 35  LEU c CD2 1 
ATOM   1033 N N   . SER B 2 37  ? 146.801 148.080 114.800 1.00 99.15  ? 36  SER c N   1 
ATOM   1034 C CA  . SER B 2 37  ? 148.136 147.514 114.692 1.00 99.15  ? 36  SER c CA  1 
ATOM   1035 C C   . SER B 2 37  ? 148.843 147.582 116.031 1.00 99.15  ? 36  SER c C   1 
ATOM   1036 O O   . SER B 2 37  ? 148.556 148.448 116.856 1.00 99.15  ? 36  SER c O   1 
ATOM   1037 C CB  . SER B 2 37  ? 148.959 148.244 113.637 1.00 99.15  ? 36  SER c CB  1 
ATOM   1038 O OG  . SER B 2 37  ? 149.201 149.569 114.056 1.00 99.15  ? 36  SER c OG  1 
ATOM   1039 N N   . GLN B 2 38  ? 149.771 146.655 116.238 1.00 99.86  ? 37  GLN c N   1 
ATOM   1040 C CA  . GLN B 2 38  ? 150.620 146.691 117.416 1.00 99.86  ? 37  GLN c CA  1 
ATOM   1041 C C   . GLN B 2 38  ? 151.749 147.683 117.193 1.00 99.86  ? 37  GLN c C   1 
ATOM   1042 O O   . GLN B 2 38  ? 152.325 147.751 116.106 1.00 99.86  ? 37  GLN c O   1 
ATOM   1043 C CB  . GLN B 2 38  ? 151.193 145.307 117.708 1.00 99.86  ? 37  GLN c CB  1 
ATOM   1044 C CG  . GLN B 2 38  ? 151.980 145.223 118.999 1.00 99.86  ? 37  GLN c CG  1 
ATOM   1045 C CD  . GLN B 2 38  ? 152.558 143.851 119.240 1.00 99.86  ? 37  GLN c CD  1 
ATOM   1046 O OE1 . GLN B 2 38  ? 152.435 142.959 118.404 1.00 99.86  ? 37  GLN c OE1 1 
ATOM   1047 N NE2 . GLN B 2 38  ? 153.189 143.669 120.391 1.00 99.86  ? 37  GLN c NE2 1 
ATOM   1048 N N   . ALA B 2 39  ? 152.067 148.456 118.230 1.00 107.96 ? 38  ALA c N   1 
ATOM   1049 C CA  . ALA B 2 39  ? 153.101 149.485 118.142 1.00 107.96 ? 38  ALA c CA  1 
ATOM   1050 C C   . ALA B 2 39  ? 154.471 148.815 118.151 1.00 107.96 ? 38  ALA c C   1 
ATOM   1051 O O   . ALA B 2 39  ? 155.170 148.756 119.164 1.00 107.96 ? 38  ALA c O   1 
ATOM   1052 C CB  . ALA B 2 39  ? 152.960 150.484 119.281 1.00 107.96 ? 38  ALA c CB  1 
ATOM   1053 N N   . GLY B 2 40  ? 154.865 148.308 116.983 1.00 108.74 ? 39  GLY c N   1 
ATOM   1054 C CA  . GLY B 2 40  ? 156.136 147.635 116.838 1.00 108.74 ? 39  GLY c CA  1 
ATOM   1055 C C   . GLY B 2 40  ? 157.265 148.598 116.526 1.00 108.74 ? 39  GLY c C   1 
ATOM   1056 O O   . GLY B 2 40  ? 157.090 149.812 116.443 1.00 108.74 ? 39  GLY c O   1 
ATOM   1057 N N   . ALA B 2 41  ? 158.456 148.027 116.355 1.00 104.84 ? 40  ALA c N   1 
ATOM   1058 C CA  . ALA B 2 41  ? 159.619 148.835 116.009 1.00 104.84 ? 40  ALA c CA  1 
ATOM   1059 C C   . ALA B 2 41  ? 159.625 149.174 114.526 1.00 104.84 ? 40  ALA c C   1 
ATOM   1060 O O   . ALA B 2 41  ? 159.553 150.345 114.143 1.00 104.84 ? 40  ALA c O   1 
ATOM   1061 C CB  . ALA B 2 41  ? 160.904 148.099 116.395 1.00 104.84 ? 40  ALA c CB  1 
ATOM   1062 N N   . VAL B 2 42  ? 159.699 148.158 113.678 1.00 101.26 ? 41  VAL c N   1 
ATOM   1063 C CA  . VAL B 2 42  ? 159.699 148.362 112.237 1.00 101.26 ? 41  VAL c CA  1 
ATOM   1064 C C   . VAL B 2 42  ? 158.270 148.174 111.747 1.00 101.26 ? 41  VAL c C   1 
ATOM   1065 O O   . VAL B 2 42  ? 157.631 147.178 112.106 1.00 101.26 ? 41  VAL c O   1 
ATOM   1066 C CB  . VAL B 2 42  ? 160.666 147.395 111.547 1.00 101.26 ? 41  VAL c CB  1 
ATOM   1067 C CG1 . VAL B 2 42  ? 160.672 147.625 110.051 1.00 101.26 ? 41  VAL c CG1 1 
ATOM   1068 C CG2 . VAL B 2 42  ? 162.052 147.550 112.127 1.00 101.26 ? 41  VAL c CG2 1 
ATOM   1069 N N   . PRO B 2 43  ? 157.727 149.094 110.943 1.00 98.49  ? 42  PRO c N   1 
ATOM   1070 C CA  . PRO B 2 43  ? 156.326 148.974 110.512 1.00 98.49  ? 42  PRO c CA  1 
ATOM   1071 C C   . PRO B 2 43  ? 156.047 147.810 109.584 1.00 98.49  ? 42  PRO c C   1 
ATOM   1072 O O   . PRO B 2 43  ? 154.872 147.491 109.372 1.00 98.49  ? 42  PRO c O   1 
ATOM   1073 C CB  . PRO B 2 43  ? 156.066 150.304 109.802 1.00 98.49  ? 42  PRO c CB  1 
ATOM   1074 C CG  . PRO B 2 43  ? 157.052 151.229 110.378 1.00 98.49  ? 42  PRO c CG  1 
ATOM   1075 C CD  . PRO B 2 43  ? 158.279 150.415 110.620 1.00 98.49  ? 42  PRO c CD  1 
ATOM   1076 N N   . ALA B 2 44  ? 157.068 147.170 109.019 1.00 99.29  ? 43  ALA c N   1 
ATOM   1077 C CA  . ALA B 2 44  ? 156.822 145.945 108.273 1.00 99.29  ? 43  ALA c CA  1 
ATOM   1078 C C   . ALA B 2 44  ? 156.459 144.798 109.200 1.00 99.29  ? 43  ALA c C   1 
ATOM   1079 O O   . ALA B 2 44  ? 155.760 143.868 108.787 1.00 99.29  ? 43  ALA c O   1 
ATOM   1080 C CB  . ALA B 2 44  ? 158.043 145.580 107.437 1.00 99.29  ? 43  ALA c CB  1 
ATOM   1081 N N   . LEU B 2 45  ? 156.926 144.838 110.443 1.00 103.17 ? 44  LEU c N   1 
ATOM   1082 C CA  . LEU B 2 45  ? 156.651 143.795 111.424 1.00 103.17 ? 44  LEU c CA  1 
ATOM   1083 C C   . LEU B 2 45  ? 155.611 144.312 112.410 1.00 103.17 ? 44  LEU c C   1 
ATOM   1084 O O   . LEU B 2 45  ? 155.930 144.727 113.523 1.00 103.17 ? 44  LEU c O   1 
ATOM   1085 C CB  . LEU B 2 45  ? 157.919 143.403 112.120 1.00 103.17 ? 44  LEU c CB  1 
ATOM   1086 C CG  . LEU B 2 45  ? 158.970 142.870 111.160 1.00 103.17 ? 44  LEU c CG  1 
ATOM   1087 C CD1 . LEU B 2 45  ? 160.243 142.517 111.900 1.00 103.17 ? 44  LEU c CD1 1 
ATOM   1088 C CD2 . LEU B 2 45  ? 158.408 141.686 110.432 1.00 103.17 ? 44  LEU c CD2 1 
ATOM   1089 N N   . GLU B 2 46  ? 154.349 144.265 112.003 1.00 105.03 ? 45  GLU c N   1 
ATOM   1090 C CA  . GLU B 2 46  ? 153.259 144.728 112.848 1.00 105.03 ? 45  GLU c CA  1 
ATOM   1091 C C   . GLU B 2 46  ? 152.096 143.766 112.705 1.00 105.03 ? 45  GLU c C   1 
ATOM   1092 O O   . GLU B 2 46  ? 151.629 143.517 111.591 1.00 105.03 ? 45  GLU c O   1 
ATOM   1093 C CB  . GLU B 2 46  ? 152.826 146.152 112.483 1.00 105.03 ? 45  GLU c CB  1 
ATOM   1094 C CG  . GLU B 2 46  ? 153.806 147.245 112.886 1.00 105.03 ? 45  GLU c CG  1 
ATOM   1095 C CD  . GLU B 2 46  ? 153.333 148.638 112.505 1.00 105.03 ? 45  GLU c CD  1 
ATOM   1096 O OE1 . GLU B 2 46  ? 152.319 148.758 111.786 1.00 105.03 ? 45  GLU c OE1 1 
ATOM   1097 O OE2 . GLU B 2 46  ? 153.977 149.618 112.935 1.00 105.03 ? 45  GLU c OE2 1 
ATOM   1098 N N   . LYS B 2 47  ? 151.637 143.231 113.829 1.00 100.45 ? 46  LYS c N   1 
ATOM   1099 C CA  . LYS B 2 47  ? 150.474 142.355 113.854 1.00 100.45 ? 46  LYS c CA  1 
ATOM   1100 C C   . LYS B 2 47  ? 149.234 143.172 113.531 1.00 100.45 ? 46  LYS c C   1 
ATOM   1101 O O   . LYS B 2 47  ? 148.805 143.996 114.340 1.00 100.45 ? 46  LYS c O   1 
ATOM   1102 C CB  . LYS B 2 47  ? 150.366 141.709 115.226 1.00 100.45 ? 46  LYS c CB  1 
ATOM   1103 C CG  . LYS B 2 47  ? 151.544 140.823 115.547 1.00 100.45 ? 46  LYS c CG  1 
ATOM   1104 C CD  . LYS B 2 47  ? 151.403 140.165 116.896 1.00 100.45 ? 46  LYS c CD  1 
ATOM   1105 C CE  . LYS B 2 47  ? 152.574 139.246 117.161 1.00 100.45 ? 46  LYS c CE  1 
ATOM   1106 N NZ  . LYS B 2 47  ? 153.836 140.018 117.304 1.00 100.45 ? 46  LYS c NZ  1 
ATOM   1107 N N   . ARG B 2 48  ? 148.657 142.970 112.352 1.00 99.18  ? 47  ARG c N   1 
ATOM   1108 C CA  . ARG B 2 48  ? 147.611 143.861 111.874 1.00 99.18  ? 47  ARG c CA  1 
ATOM   1109 C C   . ARG B 2 48  ? 146.248 143.192 111.926 1.00 99.18  ? 47  ARG c C   1 
ATOM   1110 O O   . ARG B 2 48  ? 146.119 141.989 111.675 1.00 99.18  ? 47  ARG c O   1 
ATOM   1111 C CB  . ARG B 2 48  ? 147.906 144.352 110.458 1.00 99.18  ? 47  ARG c CB  1 
ATOM   1112 C CG  . ARG B 2 48  ? 149.017 145.380 110.419 1.00 99.18  ? 47  ARG c CG  1 
ATOM   1113 C CD  . ARG B 2 48  ? 149.091 146.075 109.077 1.00 99.18  ? 47  ARG c CD  1 
ATOM   1114 N NE  . ARG B 2 48  ? 149.474 145.159 108.011 1.00 99.18  ? 47  ARG c NE  1 
ATOM   1115 C CZ  . ARG B 2 48  ? 150.731 144.901 107.675 1.00 99.18  ? 47  ARG c CZ  1 
ATOM   1116 N NH1 . ARG B 2 48  ? 151.723 145.489 108.326 1.00 99.18  ? 47  ARG c NH1 1 
ATOM   1117 N NH2 . ARG B 2 48  ? 150.997 144.053 106.692 1.00 99.18  ? 47  ARG c NH2 1 
ATOM   1118 N N   . VAL B 2 49  ? 145.237 143.981 112.280 1.00 89.23  ? 48  VAL c N   1 
ATOM   1119 C CA  . VAL B 2 49  ? 143.861 143.523 112.412 1.00 89.23  ? 48  VAL c CA  1 
ATOM   1120 C C   . VAL B 2 49  ? 142.976 144.520 111.688 1.00 89.23  ? 48  VAL c C   1 
ATOM   1121 O O   . VAL B 2 49  ? 142.912 145.686 112.081 1.00 89.23  ? 48  VAL c O   1 
ATOM   1122 C CB  . VAL B 2 49  ? 143.424 143.415 113.881 1.00 89.23  ? 48  VAL c CB  1 
ATOM   1123 C CG1 . VAL B 2 49  ? 141.949 143.116 113.957 1.00 89.23  ? 48  VAL c CG1 1 
ATOM   1124 C CG2 . VAL B 2 49  ? 144.210 142.356 114.608 1.00 89.23  ? 48  VAL c CG2 1 
ATOM   1125 N N   . THR B 2 50  ? 142.287 144.076 110.649 1.00 89.10  ? 49  THR c N   1 
ATOM   1126 C CA  . THR B 2 50  ? 141.384 144.937 109.909 1.00 89.10  ? 49  THR c CA  1 
ATOM   1127 C C   . THR B 2 50  ? 139.953 144.462 110.100 1.00 89.10  ? 49  THR c C   1 
ATOM   1128 O O   . THR B 2 50  ? 139.693 143.266 110.229 1.00 89.10  ? 49  THR c O   1 
ATOM   1129 C CB  . THR B 2 50  ? 141.727 144.942 108.423 1.00 89.10  ? 49  THR c CB  1 
ATOM   1130 O OG1 . THR B 2 50  ? 141.506 143.636 107.887 1.00 89.10  ? 49  THR c OG1 1 
ATOM   1131 C CG2 . THR B 2 50  ? 143.184 145.304 108.226 1.00 89.10  ? 49  THR c CG2 1 
ATOM   1132 N N   . VAL B 2 51  ? 139.026 145.409 110.110 1.00 87.08  ? 50  VAL c N   1 
ATOM   1133 C CA  . VAL B 2 51  ? 137.613 145.108 110.304 1.00 87.08  ? 50  VAL c CA  1 
ATOM   1134 C C   . VAL B 2 51  ? 136.798 146.012 109.389 1.00 87.08  ? 50  VAL c C   1 
ATOM   1135 O O   . VAL B 2 51  ? 137.125 147.190 109.209 1.00 87.08  ? 50  VAL c O   1 
ATOM   1136 C CB  . VAL B 2 51  ? 137.222 145.243 111.795 1.00 87.08  ? 50  VAL c CB  1 
ATOM   1137 C CG1 . VAL B 2 51  ? 137.554 146.611 112.340 1.00 87.08  ? 50  VAL c CG1 1 
ATOM   1138 C CG2 . VAL B 2 51  ? 135.756 144.942 112.014 1.00 87.08  ? 50  VAL c CG2 1 
ATOM   1139 N N   . SER B 2 52  ? 135.776 145.445 108.751 1.00 92.35  ? 51  SER c N   1 
ATOM   1140 C CA  . SER B 2 52  ? 134.934 146.232 107.859 1.00 92.35  ? 51  SER c CA  1 
ATOM   1141 C C   . SER B 2 52  ? 133.529 145.664 107.859 1.00 92.35  ? 51  SER c C   1 
ATOM   1142 O O   . SER B 2 52  ? 133.330 144.489 107.534 1.00 92.35  ? 51  SER c O   1 
ATOM   1143 C CB  . SER B 2 52  ? 135.493 146.242 106.443 1.00 92.35  ? 51  SER c CB  1 
ATOM   1144 O OG  . SER B 2 52  ? 135.392 144.959 105.862 1.00 92.35  ? 51  SER c OG  1 
ATOM   1145 N N   . VAL B 2 53  ? 132.566 146.498 108.231 1.00 95.00  ? 52  VAL c N   1 
ATOM   1146 C CA  . VAL B 2 53  ? 131.154 146.189 108.071 1.00 95.00  ? 52  VAL c CA  1 
ATOM   1147 C C   . VAL B 2 53  ? 130.780 146.708 106.689 1.00 95.00  ? 52  VAL c C   1 
ATOM   1148 O O   . VAL B 2 53  ? 131.544 147.467 106.085 1.00 95.00  ? 52  VAL c O   1 
ATOM   1149 C CB  . VAL B 2 53  ? 130.323 146.836 109.193 1.00 95.00  ? 52  VAL c CB  1 
ATOM   1150 C CG1 . VAL B 2 53  ? 130.206 148.308 108.966 1.00 95.00  ? 52  VAL c CG1 1 
ATOM   1151 C CG2 . VAL B 2 53  ? 128.959 146.191 109.356 1.00 95.00  ? 52  VAL c CG2 1 
ATOM   1152 N N   . SER B 2 54  ? 129.637 146.287 106.155 1.00 103.37 ? 53  SER c N   1 
ATOM   1153 C CA  . SER B 2 54  ? 129.240 146.740 104.831 1.00 103.37 ? 53  SER c CA  1 
ATOM   1154 C C   . SER B 2 54  ? 127.850 147.354 104.831 1.00 103.37 ? 53  SER c C   1 
ATOM   1155 O O   . SER B 2 54  ? 127.264 147.595 105.890 1.00 103.37 ? 53  SER c O   1 
ATOM   1156 C CB  . SER B 2 54  ? 129.295 145.585 103.833 1.00 103.37 ? 53  SER c CB  1 
ATOM   1157 O OG  . SER B 2 54  ? 128.850 146.005 102.556 1.00 103.37 ? 53  SER c OG  1 
ATOM   1158 N N   . GLN B 2 55  ? 127.334 147.620 103.640 1.00 113.47 ? 54  GLN c N   1 
ATOM   1159 C CA  . GLN B 2 55  ? 126.017 148.183 103.393 1.00 113.47 ? 54  GLN c CA  1 
ATOM   1160 C C   . GLN B 2 55  ? 125.405 147.407 102.235 1.00 113.47 ? 54  GLN c C   1 
ATOM   1161 O O   . GLN B 2 55  ? 126.125 146.729 101.496 1.00 113.47 ? 54  GLN c O   1 
ATOM   1162 C CB  . GLN B 2 55  ? 126.109 149.680 103.054 1.00 113.47 ? 54  GLN c CB  1 
ATOM   1163 C CG  . GLN B 2 55  ? 126.604 150.582 104.181 1.00 113.47 ? 54  GLN c CG  1 
ATOM   1164 C CD  . GLN B 2 55  ? 125.655 150.637 105.360 1.00 113.47 ? 54  GLN c CD  1 
ATOM   1165 O OE1 . GLN B 2 55  ? 125.961 150.141 106.441 1.00 113.47 ? 54  GLN c OE1 1 
ATOM   1166 N NE2 . GLN B 2 55  ? 124.496 151.248 105.157 1.00 113.47 ? 54  GLN c NE2 1 
ATOM   1167 N N   . PRO B 2 56  ? 124.070 147.460 102.067 1.00 114.71 ? 55  PRO c N   1 
ATOM   1168 C CA  . PRO B 2 56  ? 123.521 146.752 100.905 1.00 114.71 ? 55  PRO c CA  1 
ATOM   1169 C C   . PRO B 2 56  ? 123.784 147.486 99.595  1.00 114.71 ? 55  PRO c C   1 
ATOM   1170 O O   . PRO B 2 56  ? 123.756 146.856 98.538  1.00 114.71 ? 55  PRO c O   1 
ATOM   1171 C CB  . PRO B 2 56  ? 122.018 146.705 101.199 1.00 114.71 ? 55  PRO c CB  1 
ATOM   1172 C CG  . PRO B 2 56  ? 121.904 146.904 102.656 1.00 114.71 ? 55  PRO c CG  1 
ATOM   1173 C CD  . PRO B 2 56  ? 123.003 147.856 102.997 1.00 114.71 ? 55  PRO c CD  1 
ATOM   1174 N N   . LYS B 2 61  ? 120.348 144.022 99.127  1.00 107.56 ? 60  LYS c N   1 
ATOM   1175 C CA  . LYS B 2 61  ? 120.959 142.700 99.171  1.00 107.56 ? 60  LYS c CA  1 
ATOM   1176 C C   . LYS B 2 61  ? 120.920 142.129 100.581 1.00 107.56 ? 60  LYS c C   1 
ATOM   1177 O O   . LYS B 2 61  ? 119.876 141.690 101.057 1.00 107.56 ? 60  LYS c O   1 
ATOM   1178 C CB  . LYS B 2 61  ? 122.408 142.756 98.676  1.00 107.56 ? 60  LYS c CB  1 
ATOM   1179 C CG  . LYS B 2 61  ? 122.570 143.140 97.221  1.00 107.56 ? 60  LYS c CG  1 
ATOM   1180 C CD  . LYS B 2 61  ? 124.034 143.157 96.826  1.00 107.56 ? 60  LYS c CD  1 
ATOM   1181 C CE  . LYS B 2 61  ? 124.193 143.483 95.356  1.00 107.56 ? 60  LYS c CE  1 
ATOM   1182 N NZ  . LYS B 2 61  ? 123.776 144.881 95.058  1.00 107.56 ? 60  LYS c NZ  1 
ATOM   1183 N N   . ASN B 2 62  ? 122.074 142.154 101.241 1.00 107.74 ? 61  ASN c N   1 
ATOM   1184 C CA  . ASN B 2 62  ? 122.237 141.595 102.573 1.00 107.74 ? 61  ASN c CA  1 
ATOM   1185 C C   . ASN B 2 62  ? 123.485 142.181 103.214 1.00 107.74 ? 61  ASN c C   1 
ATOM   1186 O O   . ASN B 2 62  ? 124.404 142.623 102.523 1.00 107.74 ? 61  ASN c O   1 
ATOM   1187 C CB  . ASN B 2 62  ? 122.302 140.067 102.523 1.00 107.74 ? 61  ASN c CB  1 
ATOM   1188 C CG  . ASN B 2 62  ? 123.299 139.553 101.503 1.00 107.74 ? 61  ASN c CG  1 
ATOM   1189 O OD1 . ASN B 2 62  ? 123.979 140.323 100.828 1.00 107.74 ? 61  ASN c OD1 1 
ATOM   1190 N ND2 . ASN B 2 62  ? 123.388 138.236 101.386 1.00 107.74 ? 61  ASN c ND2 1 
ATOM   1191 N N   . TYR B 2 63  ? 123.497 142.189 104.542 1.00 101.67 ? 62  TYR c N   1 
ATOM   1192 C CA  . TYR B 2 63  ? 124.605 142.753 105.292 1.00 101.67 ? 62  TYR c CA  1 
ATOM   1193 C C   . TYR B 2 63  ? 125.814 141.828 105.249 1.00 101.67 ? 62  TYR c C   1 
ATOM   1194 O O   . TYR B 2 63  ? 125.712 140.642 104.931 1.00 101.67 ? 62  TYR c O   1 
ATOM   1195 C CB  . TYR B 2 63  ? 124.175 143.002 106.731 1.00 101.67 ? 62  TYR c CB  1 
ATOM   1196 C CG  . TYR B 2 63  ? 123.284 144.202 106.886 1.00 101.67 ? 62  TYR c CG  1 
ATOM   1197 C CD1 . TYR B 2 63  ? 123.409 145.288 106.044 1.00 101.67 ? 62  TYR c CD1 1 
ATOM   1198 C CD2 . TYR B 2 63  ? 122.259 144.215 107.819 1.00 101.67 ? 62  TYR c CD2 1 
ATOM   1199 C CE1 . TYR B 2 63  ? 122.591 146.384 106.178 1.00 101.67 ? 62  TYR c CE1 1 
ATOM   1200 C CE2 . TYR B 2 63  ? 121.428 145.305 107.952 1.00 101.67 ? 62  TYR c CE2 1 
ATOM   1201 C CZ  . TYR B 2 63  ? 121.599 146.387 107.124 1.00 101.67 ? 62  TYR c CZ  1 
ATOM   1202 O OH  . TYR B 2 63  ? 120.774 147.480 107.245 1.00 101.67 ? 62  TYR c OH  1 
ATOM   1203 N N   . LYS B 2 64  ? 126.974 142.386 105.588 1.00 97.13  ? 63  LYS c N   1 
ATOM   1204 C CA  . LYS B 2 64  ? 128.222 141.640 105.519 1.00 97.13  ? 63  LYS c CA  1 
ATOM   1205 C C   . LYS B 2 64  ? 129.241 142.276 106.446 1.00 97.13  ? 63  LYS c C   1 
ATOM   1206 O O   . LYS B 2 64  ? 129.490 143.479 106.358 1.00 97.13  ? 63  LYS c O   1 
ATOM   1207 C CB  . LYS B 2 64  ? 128.765 141.613 104.095 1.00 97.13  ? 63  LYS c CB  1 
ATOM   1208 C CG  . LYS B 2 64  ? 130.004 140.770 103.943 1.00 97.13  ? 63  LYS c CG  1 
ATOM   1209 C CD  . LYS B 2 64  ? 130.484 140.771 102.513 1.00 97.13  ? 63  LYS c CD  1 
ATOM   1210 C CE  . LYS B 2 64  ? 129.529 140.000 101.631 1.00 97.13  ? 63  LYS c CE  1 
ATOM   1211 N NZ  . LYS B 2 64  ? 129.515 138.558 101.981 1.00 97.13  ? 63  LYS c NZ  1 
ATOM   1212 N N   . VAL B 2 65  ? 129.820 141.472 107.329 1.00 91.39  ? 64  VAL c N   1 
ATOM   1213 C CA  . VAL B 2 65  ? 130.865 141.907 108.244 1.00 91.39  ? 64  VAL c CA  1 
ATOM   1214 C C   . VAL B 2 65  ? 132.068 141.016 108.002 1.00 91.39  ? 64  VAL c C   1 
ATOM   1215 O O   . VAL B 2 65  ? 131.912 139.802 107.859 1.00 91.39  ? 64  VAL c O   1 
ATOM   1216 C CB  . VAL B 2 65  ? 130.406 141.795 109.712 1.00 91.39  ? 64  VAL c CB  1 
ATOM   1217 C CG1 . VAL B 2 65  ? 131.480 142.284 110.658 1.00 91.39  ? 64  VAL c CG1 1 
ATOM   1218 C CG2 . VAL B 2 65  ? 129.112 142.536 109.934 1.00 91.39  ? 64  VAL c CG2 1 
ATOM   1219 N N   . GLN B 2 66  ? 133.263 141.591 107.942 1.00 88.31  ? 65  GLN c N   1 
ATOM   1220 C CA  . GLN B 2 66  ? 134.430 140.729 107.878 1.00 88.31  ? 65  GLN c CA  1 
ATOM   1221 C C   . GLN B 2 66  ? 135.568 141.302 108.703 1.00 88.31  ? 65  GLN c C   1 
ATOM   1222 O O   . GLN B 2 66  ? 135.704 142.518 108.866 1.00 88.31  ? 65  GLN c O   1 
ATOM   1223 C CB  . GLN B 2 66  ? 134.892 140.478 106.445 1.00 88.31  ? 65  GLN c CB  1 
ATOM   1224 C CG  . GLN B 2 66  ? 135.427 141.668 105.723 1.00 88.31  ? 65  GLN c CG  1 
ATOM   1225 C CD  . GLN B 2 66  ? 135.845 141.316 104.320 1.00 88.31  ? 65  GLN c CD  1 
ATOM   1226 O OE1 . GLN B 2 66  ? 135.781 140.155 103.920 1.00 88.31  ? 65  GLN c OE1 1 
ATOM   1227 N NE2 . GLN B 2 66  ? 136.275 142.313 103.560 1.00 88.31  ? 65  GLN c NE2 1 
ATOM   1228 N N   . VAL B 2 67  ? 136.365 140.389 109.252 1.00 85.40  ? 66  VAL c N   1 
ATOM   1229 C CA  . VAL B 2 67  ? 137.528 140.712 110.070 1.00 85.40  ? 66  VAL c CA  1 
ATOM   1230 C C   . VAL B 2 67  ? 138.703 139.928 109.520 1.00 85.40  ? 66  VAL c C   1 
ATOM   1231 O O   . VAL B 2 67  ? 138.662 138.697 109.487 1.00 85.40  ? 66  VAL c O   1 
ATOM   1232 C CB  . VAL B 2 67  ? 137.320 140.368 111.552 1.00 85.40  ? 66  VAL c CB  1 
ATOM   1233 C CG1 . VAL B 2 67  ? 138.607 140.568 112.315 1.00 85.40  ? 66  VAL c CG1 1 
ATOM   1234 C CG2 . VAL B 2 67  ? 136.214 141.200 112.151 1.00 85.40  ? 66  VAL c CG2 1 
ATOM   1235 N N   . LYS B 2 68  ? 139.746 140.627 109.098 1.00 89.33  ? 67  LYS c N   1 
ATOM   1236 C CA  . LYS B 2 68  ? 140.925 139.994 108.527 1.00 89.33  ? 67  LYS c CA  1 
ATOM   1237 C C   . LYS B 2 68  ? 142.123 140.298 109.411 1.00 89.33  ? 67  LYS c C   1 
ATOM   1238 O O   . LYS B 2 68  ? 142.529 141.454 109.532 1.00 89.33  ? 67  LYS c O   1 
ATOM   1239 C CB  . LYS B 2 68  ? 141.164 140.484 107.103 1.00 89.33  ? 67  LYS c CB  1 
ATOM   1240 C CG  . LYS B 2 68  ? 142.278 139.775 106.381 1.00 89.33  ? 67  LYS c CG  1 
ATOM   1241 C CD  . LYS B 2 68  ? 142.461 140.348 104.990 1.00 89.33  ? 67  LYS c CD  1 
ATOM   1242 C CE  . LYS B 2 68  ? 141.707 139.540 103.952 1.00 89.33  ? 67  LYS c CE  1 
ATOM   1243 N NZ  . LYS B 2 68  ? 140.252 139.843 103.940 1.00 89.33  ? 67  LYS c NZ  1 
ATOM   1244 N N   . ILE B 2 69  ? 142.689 139.265 110.019 1.00 90.83  ? 68  ILE c N   1 
ATOM   1245 C CA  . ILE B 2 69  ? 143.755 139.396 111.001 1.00 90.83  ? 68  ILE c CA  1 
ATOM   1246 C C   . ILE B 2 69  ? 144.976 138.635 110.510 1.00 90.83  ? 68  ILE c C   1 
ATOM   1247 O O   . ILE B 2 69  ? 144.872 137.466 110.120 1.00 90.83  ? 68  ILE c O   1 
ATOM   1248 C CB  . ILE B 2 69  ? 143.291 138.895 112.381 1.00 90.83  ? 68  ILE c CB  1 
ATOM   1249 C CG1 . ILE B 2 69  ? 144.442 138.831 113.368 1.00 90.83  ? 68  ILE c CG1 1 
ATOM   1250 C CG2 . ILE B 2 69  ? 142.520 137.593 112.294 1.00 90.83  ? 68  ILE c CG2 1 
ATOM   1251 C CD1 . ILE B 2 69  ? 143.960 138.576 114.738 1.00 90.83  ? 68  ILE c CD1 1 
ATOM   1252 N N   . GLN B 2 70  ? 146.132 139.292 110.510 1.00 100.72 ? 69  GLN c N   1 
ATOM   1253 C CA  . GLN B 2 70  ? 147.331 138.623 110.037 1.00 100.72 ? 69  GLN c CA  1 
ATOM   1254 C C   . GLN B 2 70  ? 148.540 139.035 110.863 1.00 100.72 ? 69  GLN c C   1 
ATOM   1255 O O   . GLN B 2 70  ? 148.693 140.203 111.238 1.00 100.72 ? 69  GLN c O   1 
ATOM   1256 C CB  . GLN B 2 70  ? 147.532 138.876 108.536 1.00 100.72 ? 69  GLN c CB  1 
ATOM   1257 C CG  . GLN B 2 70  ? 147.659 140.314 108.108 1.00 100.72 ? 69  GLN c CG  1 
ATOM   1258 C CD  . GLN B 2 70  ? 149.090 140.778 108.088 1.00 100.72 ? 69  GLN c CD  1 
ATOM   1259 O OE1 . GLN B 2 70  ? 150.006 139.984 107.887 1.00 100.72 ? 69  GLN c OE1 1 
ATOM   1260 N NE2 . GLN B 2 70  ? 149.294 142.071 108.286 1.00 100.72 ? 69  GLN c NE2 1 
ATOM   1261 N N   . ASN B 2 71  ? 149.377 138.042 111.157 1.00 107.07 ? 70  ASN c N   1 
ATOM   1262 C CA  . ASN B 2 71  ? 150.569 138.180 111.977 1.00 107.07 ? 70  ASN c CA  1 
ATOM   1263 C C   . ASN B 2 71  ? 151.761 137.721 111.157 1.00 107.07 ? 70  ASN c C   1 
ATOM   1264 O O   . ASN B 2 71  ? 151.774 136.566 110.701 1.00 107.07 ? 70  ASN c O   1 
ATOM   1265 C CB  . ASN B 2 71  ? 150.467 137.327 113.236 1.00 107.07 ? 70  ASN c CB  1 
ATOM   1266 C CG  . ASN B 2 71  ? 149.202 137.576 114.002 1.00 107.07 ? 70  ASN c CG  1 
ATOM   1267 O OD1 . ASN B 2 71  ? 148.400 136.673 114.184 1.00 107.07 ? 70  ASN c OD1 1 
ATOM   1268 N ND2 . ASN B 2 71  ? 148.999 138.804 114.436 1.00 107.07 ? 70  ASN c ND2 1 
ATOM   1269 N N   . PRO B 2 72  ? 152.760 138.559 110.918 1.00 105.22 ? 71  PRO c N   1 
ATOM   1270 C CA  . PRO B 2 72  ? 153.990 138.088 110.285 1.00 105.22 ? 71  PRO c CA  1 
ATOM   1271 C C   . PRO B 2 72  ? 155.048 137.716 111.309 1.00 105.22 ? 71  PRO c C   1 
ATOM   1272 O O   . PRO B 2 72  ? 155.084 138.233 112.425 1.00 105.22 ? 71  PRO c O   1 
ATOM   1273 C CB  . PRO B 2 72  ? 154.437 139.306 109.471 1.00 105.22 ? 71  PRO c CB  1 
ATOM   1274 C CG  . PRO B 2 72  ? 153.952 140.451 110.268 1.00 105.22 ? 71  PRO c CG  1 
ATOM   1275 C CD  . PRO B 2 72  ? 152.655 140.025 110.889 1.00 105.22 ? 71  PRO c CD  1 
ATOM   1276 N N   . THR B 2 73  ? 155.923 136.795 110.909 1.00 114.23 ? 72  THR c N   1 
ATOM   1277 C CA  . THR B 2 73  ? 157.118 136.476 111.677 1.00 114.23 ? 72  THR c CA  1 
ATOM   1278 C C   . THR B 2 73  ? 158.334 136.632 110.781 1.00 114.23 ? 72  THR c C   1 
ATOM   1279 O O   . THR B 2 73  ? 158.271 136.372 109.577 1.00 114.23 ? 72  THR c O   1 
ATOM   1280 C CB  . THR B 2 73  ? 157.095 135.058 112.248 1.00 114.23 ? 72  THR c CB  1 
ATOM   1281 O OG1 . THR B 2 73  ? 156.984 134.114 111.178 1.00 114.23 ? 72  THR c OG1 1 
ATOM   1282 C CG2 . THR B 2 73  ? 155.937 134.879 113.205 1.00 114.23 ? 72  THR c CG2 1 
ATOM   1283 N N   . ALA B 2 74  ? 159.444 137.055 111.375 1.00 116.53 ? 73  ALA c N   1 
ATOM   1284 C CA  . ALA B 2 74  ? 160.631 137.368 110.600 1.00 116.53 ? 73  ALA c CA  1 
ATOM   1285 C C   . ALA B 2 74  ? 161.877 136.909 111.333 1.00 116.53 ? 73  ALA c C   1 
ATOM   1286 O O   . ALA B 2 74  ? 161.909 136.823 112.562 1.00 116.53 ? 73  ALA c O   1 
ATOM   1287 C CB  . ALA B 2 74  ? 160.741 138.862 110.317 1.00 116.53 ? 73  ALA c CB  1 
ATOM   1288 N N   . CYS B 2 75  ? 162.913 136.633 110.550 1.00 132.93 ? 74  CYS c N   1 
ATOM   1289 C CA  . CYS B 2 75  ? 164.224 136.299 111.074 1.00 132.93 ? 74  CYS c CA  1 
ATOM   1290 C C   . CYS B 2 75  ? 165.265 137.092 110.305 1.00 132.93 ? 74  CYS c C   1 
ATOM   1291 O O   . CYS B 2 75  ? 165.077 137.420 109.132 1.00 132.93 ? 74  CYS c O   1 
ATOM   1292 C CB  . CYS B 2 75  ? 164.515 134.799 110.970 1.00 132.93 ? 74  CYS c CB  1 
ATOM   1293 S SG  . CYS B 2 75  ? 164.642 134.172 109.283 1.00 132.93 ? 74  CYS c SG  1 
ATOM   1294 N N   . THR B 2 76  ? 166.365 137.403 110.981 1.00 143.75 ? 75  THR c N   1 
ATOM   1295 C CA  . THR B 2 76  ? 167.421 138.212 110.385 1.00 143.75 ? 75  THR c CA  1 
ATOM   1296 C C   . THR B 2 76  ? 168.261 137.340 109.465 1.00 143.75 ? 75  THR c C   1 
ATOM   1297 O O   . THR B 2 76  ? 169.005 136.471 109.926 1.00 143.75 ? 75  THR c O   1 
ATOM   1298 C CB  . THR B 2 76  ? 168.286 138.840 111.469 1.00 143.75 ? 75  THR c CB  1 
ATOM   1299 O OG1 . THR B 2 76  ? 168.906 137.804 112.239 1.00 143.75 ? 75  THR c OG1 1 
ATOM   1300 C CG2 . THR B 2 76  ? 167.439 139.706 112.382 1.00 143.75 ? 75  THR c CG2 1 
ATOM   1301 N N   . ALA B 2 77  ? 168.133 137.565 108.160 1.00 154.72 ? 76  ALA c N   1 
ATOM   1302 C CA  . ALA B 2 77  ? 169.015 136.919 107.202 1.00 154.72 ? 76  ALA c CA  1 
ATOM   1303 C C   . ALA B 2 77  ? 170.430 137.450 107.370 1.00 154.72 ? 76  ALA c C   1 
ATOM   1304 O O   . ALA B 2 77  ? 170.635 138.629 107.669 1.00 154.72 ? 76  ALA c O   1 
ATOM   1305 C CB  . ALA B 2 77  ? 168.524 137.160 105.776 1.00 154.72 ? 76  ALA c CB  1 
ATOM   1306 N N   . ASN B 2 78  ? 171.412 136.567 107.179 1.00 164.10 ? 77  ASN c N   1 
ATOM   1307 C CA  . ASN B 2 78  ? 172.791 136.929 107.483 1.00 164.10 ? 77  ASN c CA  1 
ATOM   1308 C C   . ASN B 2 78  ? 173.375 137.841 106.412 1.00 164.10 ? 77  ASN c C   1 
ATOM   1309 O O   . ASN B 2 78  ? 174.325 138.586 106.677 1.00 164.10 ? 77  ASN c O   1 
ATOM   1310 C CB  . ASN B 2 78  ? 173.639 135.667 107.634 1.00 164.10 ? 77  ASN c CB  1 
ATOM   1311 C CG  . ASN B 2 78  ? 174.827 135.861 108.562 1.00 164.10 ? 77  ASN c CG  1 
ATOM   1312 O OD1 . ASN B 2 78  ? 175.457 134.890 108.976 1.00 164.10 ? 77  ASN c OD1 1 
ATOM   1313 N ND2 . ASN B 2 78  ? 175.119 137.108 108.917 1.00 164.10 ? 77  ASN c ND2 1 
ATOM   1314 N N   . GLY B 2 79  ? 172.818 137.808 105.205 1.00 163.44 ? 78  GLY c N   1 
ATOM   1315 C CA  . GLY B 2 79  ? 173.345 138.633 104.137 1.00 163.44 ? 78  GLY c CA  1 
ATOM   1316 C C   . GLY B 2 79  ? 172.965 140.095 104.247 1.00 163.44 ? 78  GLY c C   1 
ATOM   1317 O O   . GLY B 2 79  ? 173.537 140.940 103.554 1.00 163.44 ? 78  GLY c O   1 
ATOM   1318 N N   . SER B 2 80  ? 172.008 140.420 105.106 1.00 161.39 ? 79  SER c N   1 
ATOM   1319 C CA  . SER B 2 80  ? 171.507 141.778 105.233 1.00 161.39 ? 79  SER c CA  1 
ATOM   1320 C C   . SER B 2 80  ? 171.513 142.211 106.690 1.00 161.39 ? 79  SER c C   1 
ATOM   1321 O O   . SER B 2 80  ? 171.631 141.382 107.597 1.00 161.39 ? 79  SER c O   1 
ATOM   1322 C CB  . SER B 2 80  ? 170.094 141.891 104.666 1.00 161.39 ? 79  SER c CB  1 
ATOM   1323 O OG  . SER B 2 80  ? 169.182 141.132 105.439 1.00 161.39 ? 79  SER c OG  1 
ATOM   1324 N N   . CYS B 2 81  ? 171.387 143.521 106.906 1.00 155.52 ? 80  CYS c N   1 
ATOM   1325 C CA  . CYS B 2 81  ? 171.289 144.042 108.264 1.00 155.52 ? 80  CYS c CA  1 
ATOM   1326 C C   . CYS B 2 81  ? 169.837 144.143 108.711 1.00 155.52 ? 80  CYS c C   1 
ATOM   1327 O O   . CYS B 2 81  ? 169.517 143.867 109.872 1.00 155.52 ? 80  CYS c O   1 
ATOM   1328 C CB  . CYS B 2 81  ? 171.969 145.405 108.346 1.00 155.52 ? 80  CYS c CB  1 
ATOM   1329 S SG  . CYS B 2 81  ? 171.179 146.674 107.340 1.00 155.52 ? 80  CYS c SG  1 
ATOM   1330 N N   . ASP B 2 82  ? 168.949 144.540 107.807 1.00 149.39 ? 81  ASP c N   1 
ATOM   1331 C CA  . ASP B 2 82  ? 167.542 144.677 108.149 1.00 149.39 ? 81  ASP c CA  1 
ATOM   1332 C C   . ASP B 2 82  ? 166.870 143.308 108.224 1.00 149.39 ? 81  ASP c C   1 
ATOM   1333 O O   . ASP B 2 82  ? 167.263 142.384 107.507 1.00 149.39 ? 81  ASP c O   1 
ATOM   1334 C CB  . ASP B 2 82  ? 166.827 145.562 107.131 1.00 149.39 ? 81  ASP c CB  1 
ATOM   1335 C CG  . ASP B 2 82  ? 167.035 145.108 105.692 1.00 149.39 ? 81  ASP c CG  1 
ATOM   1336 O OD1 . ASP B 2 82  ? 167.868 144.215 105.436 1.00 149.39 ? 81  ASP c OD1 1 
ATOM   1337 O OD2 . ASP B 2 82  ? 166.351 145.652 104.802 1.00 149.39 ? 81  ASP c OD2 1 
ATOM   1338 N N   . PRO B 2 83  ? 165.882 143.136 109.098 1.00 132.98 ? 82  PRO c N   1 
ATOM   1339 C CA  . PRO B 2 83  ? 165.139 141.874 109.113 1.00 132.98 ? 82  PRO c CA  1 
ATOM   1340 C C   . PRO B 2 83  ? 164.183 141.798 107.936 1.00 132.98 ? 82  PRO c C   1 
ATOM   1341 O O   . PRO B 2 83  ? 163.641 142.808 107.484 1.00 132.98 ? 82  PRO c O   1 
ATOM   1342 C CB  . PRO B 2 83  ? 164.389 141.924 110.446 1.00 132.98 ? 82  PRO c CB  1 
ATOM   1343 C CG  . PRO B 2 83  ? 164.230 143.367 110.721 1.00 132.98 ? 82  PRO c CG  1 
ATOM   1344 C CD  . PRO B 2 83  ? 165.465 144.030 110.190 1.00 132.98 ? 82  PRO c CD  1 
ATOM   1345 N N   . SER B 2 84  ? 163.984 140.585 107.435 1.00 128.94 ? 83  SER c N   1 
ATOM   1346 C CA  . SER B 2 84  ? 163.129 140.341 106.284 1.00 128.94 ? 83  SER c CA  1 
ATOM   1347 C C   . SER B 2 84  ? 162.001 139.402 106.673 1.00 128.94 ? 83  SER c C   1 
ATOM   1348 O O   . SER B 2 84  ? 162.210 138.443 107.421 1.00 128.94 ? 83  SER c O   1 
ATOM   1349 C CB  . SER B 2 84  ? 163.921 139.739 105.128 1.00 128.94 ? 83  SER c CB  1 
ATOM   1350 O OG  . SER B 2 84  ? 164.375 138.440 105.461 1.00 128.94 ? 83  SER c OG  1 
ATOM   1351 N N   . VAL B 2 85  ? 160.811 139.669 106.143 1.00 117.04 ? 84  VAL c N   1 
ATOM   1352 C CA  . VAL B 2 85  ? 159.635 138.896 106.514 1.00 117.04 ? 84  VAL c CA  1 
ATOM   1353 C C   . VAL B 2 85  ? 159.662 137.555 105.797 1.00 117.04 ? 84  VAL c C   1 
ATOM   1354 O O   . VAL B 2 85  ? 159.834 137.491 104.574 1.00 117.04 ? 84  VAL c O   1 
ATOM   1355 C CB  . VAL B 2 85  ? 158.361 139.676 106.173 1.00 117.04 ? 84  VAL c CB  1 
ATOM   1356 C CG1 . VAL B 2 85  ? 157.158 138.924 106.651 1.00 117.04 ? 84  VAL c CG1 1 
ATOM   1357 C CG2 . VAL B 2 85  ? 158.414 141.052 106.780 1.00 117.04 ? 84  VAL c CG2 1 
ATOM   1358 N N   . THR B 2 86  ? 159.483 136.476 106.554 1.00 115.62 ? 85  THR c N   1 
ATOM   1359 C CA  . THR B 2 86  ? 159.503 135.132 105.995 1.00 115.62 ? 85  THR c CA  1 
ATOM   1360 C C   . THR B 2 86  ? 158.110 134.585 105.728 1.00 115.62 ? 85  THR c C   1 
ATOM   1361 O O   . THR B 2 86  ? 157.833 134.106 104.627 1.00 115.62 ? 85  THR c O   1 
ATOM   1362 C CB  . THR B 2 86  ? 160.242 134.183 106.937 1.00 115.62 ? 85  THR c CB  1 
ATOM   1363 O OG1 . THR B 2 86  ? 159.527 134.100 108.173 1.00 115.62 ? 85  THR c OG1 1 
ATOM   1364 C CG2 . THR B 2 86  ? 161.635 134.698 107.205 1.00 115.62 ? 85  THR c CG2 1 
ATOM   1365 N N   . ARG B 2 87  ? 157.225 134.640 106.718 1.00 114.38 ? 86  ARG c N   1 
ATOM   1366 C CA  . ARG B 2 87  ? 155.925 134.005 106.591 1.00 114.38 ? 86  ARG c CA  1 
ATOM   1367 C C   . ARG B 2 87  ? 154.906 134.748 107.441 1.00 114.38 ? 86  ARG c C   1 
ATOM   1368 O O   . ARG B 2 87  ? 155.255 135.511 108.347 1.00 114.38 ? 86  ARG c O   1 
ATOM   1369 C CB  . ARG B 2 87  ? 156.003 132.531 106.994 1.00 114.38 ? 86  ARG c CB  1 
ATOM   1370 C CG  . ARG B 2 87  ? 156.408 132.327 108.432 1.00 114.38 ? 86  ARG c CG  1 
ATOM   1371 C CD  . ARG B 2 87  ? 156.616 130.863 108.746 1.00 114.38 ? 86  ARG c CD  1 
ATOM   1372 N NE  . ARG B 2 87  ? 156.918 130.654 110.157 1.00 114.38 ? 86  ARG c NE  1 
ATOM   1373 C CZ  . ARG B 2 87  ? 158.143 130.674 110.667 1.00 114.38 ? 86  ARG c CZ  1 
ATOM   1374 N NH1 . ARG B 2 87  ? 159.186 130.885 109.880 1.00 114.38 ? 86  ARG c NH1 1 
ATOM   1375 N NH2 . ARG B 2 87  ? 158.326 130.477 111.964 1.00 114.38 ? 86  ARG c NH2 1 
ATOM   1376 N N   . GLN B 2 88  ? 153.638 134.527 107.123 1.00 108.74 ? 87  GLN c N   1 
ATOM   1377 C CA  . GLN B 2 88  ? 152.524 135.122 107.840 1.00 108.74 ? 87  GLN c CA  1 
ATOM   1378 C C   . GLN B 2 88  ? 151.671 134.024 108.454 1.00 108.74 ? 87  GLN c C   1 
ATOM   1379 O O   . GLN B 2 88  ? 151.984 132.838 108.370 1.00 108.74 ? 87  GLN c O   1 
ATOM   1380 C CB  . GLN B 2 88  ? 151.651 135.986 106.927 1.00 108.74 ? 87  GLN c CB  1 
ATOM   1381 C CG  . GLN B 2 88  ? 152.240 137.312 106.517 1.00 108.74 ? 87  GLN c CG  1 
ATOM   1382 C CD  . GLN B 2 88  ? 153.264 137.164 105.434 1.00 108.74 ? 87  GLN c CD  1 
ATOM   1383 O OE1 . GLN B 2 88  ? 154.421 137.513 105.610 1.00 108.74 ? 87  GLN c OE1 1 
ATOM   1384 N NE2 . GLN B 2 88  ? 152.847 136.625 104.302 1.00 108.74 ? 87  GLN c NE2 1 
ATOM   1385 N N   . ALA B 2 89  ? 150.585 134.442 109.088 1.00 103.25 ? 88  ALA c N   1 
ATOM   1386 C CA  . ALA B 2 89  ? 149.526 133.525 109.505 1.00 103.25 ? 88  ALA c CA  1 
ATOM   1387 C C   . ALA B 2 89  ? 148.203 134.259 109.303 1.00 103.25 ? 88  ALA c C   1 
ATOM   1388 O O   . ALA B 2 89  ? 147.726 134.954 110.200 1.00 103.25 ? 88  ALA c O   1 
ATOM   1389 C CB  . ALA B 2 89  ? 149.716 133.079 110.943 1.00 103.25 ? 88  ALA c CB  1 
ATOM   1390 N N   . TYR B 2 90  ? 147.612 134.095 108.128 1.00 95.70  ? 89  TYR c N   1 
ATOM   1391 C CA  . TYR B 2 90  ? 146.394 134.815 107.807 1.00 95.70  ? 89  TYR c CA  1 
ATOM   1392 C C   . TYR B 2 90  ? 145.198 134.179 108.492 1.00 95.70  ? 89  TYR c C   1 
ATOM   1393 O O   . TYR B 2 90  ? 145.186 132.980 108.780 1.00 95.70  ? 89  TYR c O   1 
ATOM   1394 C CB  . TYR B 2 90  ? 146.163 134.834 106.302 1.00 95.70  ? 89  TYR c CB  1 
ATOM   1395 C CG  . TYR B 2 90  ? 147.215 135.586 105.543 1.00 95.70  ? 89  TYR c CG  1 
ATOM   1396 C CD1 . TYR B 2 90  ? 147.186 136.967 105.471 1.00 95.70  ? 89  TYR c CD1 1 
ATOM   1397 C CD2 . TYR B 2 90  ? 148.236 134.913 104.892 1.00 95.70  ? 89  TYR c CD2 1 
ATOM   1398 C CE1 . TYR B 2 90  ? 148.146 137.660 104.777 1.00 95.70  ? 89  TYR c CE1 1 
ATOM   1399 C CE2 . TYR B 2 90  ? 149.200 135.594 104.195 1.00 95.70  ? 89  TYR c CE2 1 
ATOM   1400 C CZ  . TYR B 2 90  ? 149.152 136.968 104.140 1.00 95.70  ? 89  TYR c CZ  1 
ATOM   1401 O OH  . TYR B 2 90  ? 150.115 137.655 103.444 1.00 95.70  ? 89  TYR c OH  1 
ATOM   1402 N N   . ALA B 2 91  ? 144.182 134.999 108.744 1.00 90.09  ? 90  ALA c N   1 
ATOM   1403 C CA  . ALA B 2 91  ? 142.899 134.518 109.227 1.00 90.09  ? 90  ALA c CA  1 
ATOM   1404 C C   . ALA B 2 91  ? 141.856 135.565 108.895 1.00 90.09  ? 90  ALA c C   1 
ATOM   1405 O O   . ALA B 2 91  ? 142.173 136.750 108.814 1.00 90.09  ? 90  ALA c O   1 
ATOM   1406 C CB  . ALA B 2 91  ? 142.919 134.261 110.733 1.00 90.09  ? 90  ALA c CB  1 
ATOM   1407 N N   . ASP B 2 92  ? 140.613 135.127 108.713 1.00 90.48  ? 91  ASP c N   1 
ATOM   1408 C CA  . ASP B 2 92  ? 139.524 136.062 108.475 1.00 90.48  ? 91  ASP c CA  1 
ATOM   1409 C C   . ASP B 2 92  ? 138.194 135.410 108.809 1.00 90.48  ? 91  ASP c C   1 
ATOM   1410 O O   . ASP B 2 92  ? 138.022 134.206 108.633 1.00 90.48  ? 91  ASP c O   1 
ATOM   1411 C CB  . ASP B 2 92  ? 139.519 136.565 107.029 1.00 90.48  ? 91  ASP c CB  1 
ATOM   1412 C CG  . ASP B 2 92  ? 139.610 135.449 106.029 1.00 90.48  ? 91  ASP c CG  1 
ATOM   1413 O OD1 . ASP B 2 92  ? 139.857 134.301 106.447 1.00 90.48  ? 91  ASP c OD1 1 
ATOM   1414 O OD2 . ASP B 2 92  ? 139.422 135.718 104.824 1.00 90.48  ? 91  ASP c OD2 1 
ATOM   1415 N N   . VAL B 2 93  ? 137.275 136.217 109.317 1.00 86.82  ? 92  VAL c N   1 
ATOM   1416 C CA  . VAL B 2 93  ? 135.905 135.797 109.558 1.00 86.82  ? 92  VAL c CA  1 
ATOM   1417 C C   . VAL B 2 93  ? 135.019 136.642 108.655 1.00 86.82  ? 92  VAL c C   1 
ATOM   1418 O O   . VAL B 2 93  ? 135.356 137.784 108.321 1.00 86.82  ? 92  VAL c O   1 
ATOM   1419 C CB  . VAL B 2 93  ? 135.503 135.926 111.046 1.00 86.82  ? 92  VAL c CB  1 
ATOM   1420 C CG1 . VAL B 2 93  ? 136.579 135.345 111.921 1.00 86.82  ? 92  VAL c CG1 1 
ATOM   1421 C CG2 . VAL B 2 93  ? 135.244 137.338 111.450 1.00 86.82  ? 92  VAL c CG2 1 
ATOM   1422 N N   . THR B 2 94  ? 133.924 136.044 108.186 1.00 88.38  ? 93  THR c N   1 
ATOM   1423 C CA  . THR B 2 94  ? 132.949 136.737 107.339 1.00 88.38  ? 93  THR c CA  1 
ATOM   1424 C C   . THR B 2 94  ? 131.554 136.356 107.818 1.00 88.38  ? 93  THR c C   1 
ATOM   1425 O O   . THR B 2 94  ? 131.052 135.281 107.486 1.00 88.38  ? 93  THR c O   1 
ATOM   1426 C CB  . THR B 2 94  ? 133.107 136.396 105.859 1.00 88.38  ? 93  THR c CB  1 
ATOM   1427 O OG1 . THR B 2 94  ? 133.041 134.979 105.685 1.00 88.38  ? 93  THR c OG1 1 
ATOM   1428 C CG2 . THR B 2 94  ? 134.404 136.932 105.264 1.00 88.38  ? 93  THR c CG2 1 
ATOM   1429 N N   . PHE B 2 95  ? 130.930 137.243 108.577 1.00 87.91  ? 94  PHE c N   1 
ATOM   1430 C CA  . PHE B 2 95  ? 129.541 137.088 108.965 1.00 87.91  ? 94  PHE c CA  1 
ATOM   1431 C C   . PHE B 2 95  ? 128.641 137.655 107.881 1.00 87.91  ? 94  PHE c C   1 
ATOM   1432 O O   . PHE B 2 95  ? 128.943 138.696 107.292 1.00 87.91  ? 94  PHE c O   1 
ATOM   1433 C CB  . PHE B 2 95  ? 129.271 137.811 110.277 1.00 87.91  ? 94  PHE c CB  1 
ATOM   1434 C CG  . PHE B 2 95  ? 130.052 137.277 111.418 1.00 87.91  ? 94  PHE c CG  1 
ATOM   1435 C CD1 . PHE B 2 95  ? 129.637 136.144 112.076 1.00 87.91  ? 94  PHE c CD1 1 
ATOM   1436 C CD2 . PHE B 2 95  ? 131.207 137.906 111.832 1.00 87.91  ? 94  PHE c CD2 1 
ATOM   1437 C CE1 . PHE B 2 95  ? 130.357 135.639 113.127 1.00 87.91  ? 94  PHE c CE1 1 
ATOM   1438 C CE2 . PHE B 2 95  ? 131.932 137.413 112.886 1.00 87.91  ? 94  PHE c CE2 1 
ATOM   1439 C CZ  . PHE B 2 95  ? 131.509 136.276 113.534 1.00 87.91  ? 94  PHE c CZ  1 
ATOM   1440 N N   . SER B 2 96  ? 127.524 136.978 107.632 1.00 91.76  ? 95  SER c N   1 
ATOM   1441 C CA  . SER B 2 96  ? 126.554 137.421 106.641 1.00 91.76  ? 95  SER c CA  1 
ATOM   1442 C C   . SER B 2 96  ? 125.158 137.296 107.226 1.00 91.76  ? 95  SER c C   1 
ATOM   1443 O O   . SER B 2 96  ? 124.709 136.188 107.530 1.00 91.76  ? 95  SER c O   1 
ATOM   1444 C CB  . SER B 2 96  ? 126.670 136.606 105.356 1.00 91.76  ? 95  SER c CB  1 
ATOM   1445 O OG  . SER B 2 96  ? 125.688 137.009 104.422 1.00 91.76  ? 95  SER c OG  1 
ATOM   1446 N N   . PHE B 2 97  ? 124.479 138.421 107.376 1.00 94.66  ? 96  PHE c N   1 
ATOM   1447 C CA  . PHE B 2 97  ? 123.125 138.471 107.899 1.00 94.66  ? 96  PHE c CA  1 
ATOM   1448 C C   . PHE B 2 97  ? 122.191 138.991 106.816 1.00 94.66  ? 96  PHE c C   1 
ATOM   1449 O O   . PHE B 2 97  ? 122.609 139.285 105.697 1.00 94.66  ? 96  PHE c O   1 
ATOM   1450 C CB  . PHE B 2 97  ? 123.069 139.359 109.136 1.00 94.66  ? 96  PHE c CB  1 
ATOM   1451 C CG  . PHE B 2 97  ? 123.972 138.914 110.235 1.00 94.66  ? 96  PHE c CG  1 
ATOM   1452 C CD1 . PHE B 2 97  ? 123.615 137.870 111.061 1.00 94.66  ? 96  PHE c CD1 1 
ATOM   1453 C CD2 . PHE B 2 97  ? 125.178 139.548 110.446 1.00 94.66  ? 96  PHE c CD2 1 
ATOM   1454 C CE1 . PHE B 2 97  ? 124.449 137.466 112.080 1.00 94.66  ? 96  PHE c CE1 1 
ATOM   1455 C CE2 . PHE B 2 97  ? 126.013 139.149 111.458 1.00 94.66  ? 96  PHE c CE2 1 
ATOM   1456 C CZ  . PHE B 2 97  ? 125.648 138.108 112.277 1.00 94.66  ? 96  PHE c CZ  1 
ATOM   1457 N N   . THR B 2 98  ? 120.915 139.114 107.156 1.00 97.76  ? 97  THR c N   1 
ATOM   1458 C CA  . THR B 2 98  ? 119.917 139.654 106.244 1.00 97.76  ? 97  THR c CA  1 
ATOM   1459 C C   . THR B 2 98  ? 119.301 140.912 106.841 1.00 97.76  ? 97  THR c C   1 
ATOM   1460 O O   . THR B 2 98  ? 119.667 141.347 107.933 1.00 97.76  ? 97  THR c O   1 
ATOM   1461 C CB  . THR B 2 98  ? 118.828 138.628 105.942 1.00 97.76  ? 97  THR c CB  1 
ATOM   1462 O OG1 . THR B 2 98  ? 118.167 138.276 107.160 1.00 97.76  ? 97  THR c OG1 1 
ATOM   1463 C CG2 . THR B 2 98  ? 119.424 137.387 105.316 1.00 97.76  ? 97  THR c CG2 1 
ATOM   1464 N N   . GLN B 2 99  ? 118.350 141.493 106.104 1.00 104.10 ? 98  GLN c N   1 
ATOM   1465 C CA  . GLN B 2 99  ? 117.686 142.707 106.564 1.00 104.10 ? 98  GLN c CA  1 
ATOM   1466 C C   . GLN B 2 99  ? 116.834 142.459 107.796 1.00 104.10 ? 98  GLN c C   1 
ATOM   1467 O O   . GLN B 2 99  ? 116.682 143.355 108.631 1.00 104.10 ? 98  GLN c O   1 
ATOM   1468 C CB  . GLN B 2 99  ? 116.805 143.299 105.464 1.00 104.10 ? 98  GLN c CB  1 
ATOM   1469 C CG  . GLN B 2 99  ? 117.522 144.121 104.411 1.00 104.10 ? 98  GLN c CG  1 
ATOM   1470 C CD  . GLN B 2 99  ? 118.322 143.284 103.446 1.00 104.10 ? 98  GLN c CD  1 
ATOM   1471 O OE1 . GLN B 2 99  ? 119.535 143.443 103.328 1.00 104.10 ? 98  GLN c OE1 1 
ATOM   1472 N NE2 . GLN B 2 99  ? 117.646 142.387 102.742 1.00 104.10 ? 98  GLN c NE2 1 
ATOM   1473 N N   . TYR B 2 100 ? 116.275 141.261 107.932 1.00 104.11 ? 99  TYR c N   1 
ATOM   1474 C CA  . TYR B 2 100 ? 115.329 140.970 108.996 1.00 104.11 ? 99  TYR c CA  1 
ATOM   1475 C C   . TYR B 2 100 ? 115.979 140.253 110.168 1.00 104.11 ? 99  TYR c C   1 
ATOM   1476 O O   . TYR B 2 100 ? 115.288 139.579 110.936 1.00 104.11 ? 99  TYR c O   1 
ATOM   1477 C CB  . TYR B 2 100 ? 114.167 140.141 108.452 1.00 104.11 ? 99  TYR c CB  1 
ATOM   1478 C CG  . TYR B 2 100 ? 113.270 140.879 107.485 1.00 104.11 ? 99  TYR c CG  1 
ATOM   1479 C CD1 . TYR B 2 100 ? 113.275 142.265 107.412 1.00 104.11 ? 99  TYR c CD1 1 
ATOM   1480 C CD2 . TYR B 2 100 ? 112.422 140.184 106.638 1.00 104.11 ? 99  TYR c CD2 1 
ATOM   1481 C CE1 . TYR B 2 100 ? 112.461 142.933 106.529 1.00 104.11 ? 99  TYR c CE1 1 
ATOM   1482 C CE2 . TYR B 2 100 ? 111.602 140.845 105.751 1.00 104.11 ? 99  TYR c CE2 1 
ATOM   1483 C CZ  . TYR B 2 100 ? 111.627 142.218 105.703 1.00 104.11 ? 99  TYR c CZ  1 
ATOM   1484 O OH  . TYR B 2 100 ? 110.811 142.880 104.820 1.00 104.11 ? 99  TYR c OH  1 
ATOM   1485 N N   . SER B 2 101 ? 117.289 140.380 110.321 1.00 101.08 ? 100 SER c N   1 
ATOM   1486 C CA  . SER B 2 101 ? 117.987 139.719 111.410 1.00 101.08 ? 100 SER c CA  1 
ATOM   1487 C C   . SER B 2 101 ? 117.784 140.505 112.694 1.00 101.08 ? 100 SER c C   1 
ATOM   1488 O O   . SER B 2 101 ? 118.024 141.713 112.732 1.00 101.08 ? 100 SER c O   1 
ATOM   1489 C CB  . SER B 2 101 ? 119.472 139.611 111.086 1.00 101.08 ? 100 SER c CB  1 
ATOM   1490 O OG  . SER B 2 101 ? 119.676 138.865 109.900 1.00 101.08 ? 100 SER c OG  1 
ATOM   1491 N N   . THR B 2 102 ? 117.351 139.827 113.749 1.00 107.66 ? 101 THR c N   1 
ATOM   1492 C CA  . THR B 2 102 ? 117.154 140.512 115.015 1.00 107.66 ? 101 THR c CA  1 
ATOM   1493 C C   . THR B 2 102 ? 118.493 140.707 115.721 1.00 107.66 ? 101 THR c C   1 
ATOM   1494 O O   . THR B 2 102 ? 119.548 140.296 115.240 1.00 107.66 ? 101 THR c O   1 
ATOM   1495 C CB  . THR B 2 102 ? 116.191 139.737 115.904 1.00 107.66 ? 101 THR c CB  1 
ATOM   1496 O OG1 . THR B 2 102 ? 116.767 138.471 116.236 1.00 107.66 ? 101 THR c OG1 1 
ATOM   1497 C CG2 . THR B 2 102 ? 114.880 139.510 115.185 1.00 107.66 ? 101 THR c CG2 1 
ATOM   1498 N N   . ASP B 2 103 ? 118.448 141.338 116.890 1.00 110.25 ? 102 ASP c N   1 
ATOM   1499 C CA  . ASP B 2 103 ? 119.670 141.606 117.638 1.00 110.25 ? 102 ASP c CA  1 
ATOM   1500 C C   . ASP B 2 103 ? 120.175 140.344 118.326 1.00 110.25 ? 102 ASP c C   1 
ATOM   1501 O O   . ASP B 2 103 ? 121.373 140.031 118.270 1.00 110.25 ? 102 ASP c O   1 
ATOM   1502 C CB  . ASP B 2 103 ? 119.405 142.711 118.662 1.00 110.25 ? 102 ASP c CB  1 
ATOM   1503 C CG  . ASP B 2 103 ? 120.676 143.309 119.239 1.00 110.25 ? 102 ASP c CG  1 
ATOM   1504 O OD1 . ASP B 2 103 ? 121.785 142.894 118.847 1.00 110.25 ? 102 ASP c OD1 1 
ATOM   1505 O OD2 . ASP B 2 103 ? 120.558 144.210 120.096 1.00 110.25 ? 102 ASP c OD2 1 
ATOM   1506 N N   . GLU B 2 104 ? 119.265 139.622 118.987 1.00 110.94 ? 103 GLU c N   1 
ATOM   1507 C CA  . GLU B 2 104 ? 119.623 138.410 119.713 1.00 110.94 ? 103 GLU c CA  1 
ATOM   1508 C C   . GLU B 2 104 ? 120.162 137.342 118.775 1.00 110.94 ? 103 GLU c C   1 
ATOM   1509 O O   . GLU B 2 104 ? 121.151 136.665 119.087 1.00 110.94 ? 103 GLU c O   1 
ATOM   1510 C CB  . GLU B 2 104 ? 118.399 137.885 120.460 1.00 110.94 ? 103 GLU c CB  1 
ATOM   1511 C CG  . GLU B 2 104 ? 118.651 136.633 121.268 1.00 110.94 ? 103 GLU c CG  1 
ATOM   1512 C CD  . GLU B 2 104 ? 119.509 136.892 122.484 1.00 110.94 ? 103 GLU c CD  1 
ATOM   1513 O OE1 . GLU B 2 104 ? 119.453 138.019 123.017 1.00 110.94 ? 103 GLU c OE1 1 
ATOM   1514 O OE2 . GLU B 2 104 ? 120.241 135.973 122.905 1.00 110.94 ? 103 GLU c OE2 1 
ATOM   1515 N N   . GLU B 2 105 ? 119.543 137.204 117.605 1.00 108.09 ? 104 GLU c N   1 
ATOM   1516 C CA  . GLU B 2 105 ? 119.966 136.194 116.652 1.00 108.09 ? 104 GLU c CA  1 
ATOM   1517 C C   . GLU B 2 105 ? 121.303 136.544 116.016 1.00 108.09 ? 104 GLU c C   1 
ATOM   1518 O O   . GLU B 2 105 ? 122.034 135.639 115.606 1.00 108.09 ? 104 GLU c O   1 
ATOM   1519 C CB  . GLU B 2 105 ? 118.875 136.017 115.598 1.00 108.09 ? 104 GLU c CB  1 
ATOM   1520 C CG  . GLU B 2 105 ? 118.948 134.733 114.805 1.00 108.09 ? 104 GLU c CG  1 
ATOM   1521 C CD  . GLU B 2 105 ? 119.794 134.857 113.567 1.00 108.09 ? 104 GLU c CD  1 
ATOM   1522 O OE1 . GLU B 2 105 ? 119.877 135.974 113.020 1.00 108.09 ? 104 GLU c OE1 1 
ATOM   1523 O OE2 . GLU B 2 105 ? 120.374 133.836 113.144 1.00 108.09 ? 104 GLU c OE2 1 
ATOM   1524 N N   . ARG B 2 106 ? 121.655 137.827 115.951 1.00 100.40 ? 105 ARG c N   1 
ATOM   1525 C CA  . ARG B 2 106 ? 122.999 138.177 115.515 1.00 100.40 ? 105 ARG c CA  1 
ATOM   1526 C C   . ARG B 2 106 ? 124.023 137.912 116.604 1.00 100.40 ? 105 ARG c C   1 
ATOM   1527 O O   . ARG B 2 106 ? 125.129 137.453 116.309 1.00 100.40 ? 105 ARG c O   1 
ATOM   1528 C CB  . ARG B 2 106 ? 123.072 139.639 115.088 1.00 100.40 ? 105 ARG c CB  1 
ATOM   1529 C CG  . ARG B 2 106 ? 122.427 139.938 113.762 1.00 100.40 ? 105 ARG c CG  1 
ATOM   1530 C CD  . ARG B 2 106 ? 122.764 141.341 113.319 1.00 100.40 ? 105 ARG c CD  1 
ATOM   1531 N NE  . ARG B 2 106 ? 122.239 142.328 114.251 1.00 100.40 ? 105 ARG c NE  1 
ATOM   1532 C CZ  . ARG B 2 106 ? 121.034 142.868 114.153 1.00 100.40 ? 105 ARG c CZ  1 
ATOM   1533 N NH1 . ARG B 2 106 ? 120.239 142.521 113.156 1.00 100.40 ? 105 ARG c NH1 1 
ATOM   1534 N NH2 . ARG B 2 106 ? 120.627 143.755 115.046 1.00 100.40 ? 105 ARG c NH2 1 
ATOM   1535 N N   . ALA B 2 107 ? 123.682 138.201 117.863 1.00 103.25 ? 106 ALA c N   1 
ATOM   1536 C CA  . ALA B 2 107 ? 124.656 138.021 118.937 1.00 103.25 ? 106 ALA c CA  1 
ATOM   1537 C C   . ALA B 2 107 ? 124.932 136.551 119.209 1.00 103.25 ? 106 ALA c C   1 
ATOM   1538 O O   . ALA B 2 107 ? 126.041 136.195 119.643 1.00 103.25 ? 106 ALA c O   1 
ATOM   1539 C CB  . ALA B 2 107 ? 124.167 138.702 120.209 1.00 103.25 ? 106 ALA c CB  1 
ATOM   1540 N N   . PHE B 2 108 ? 123.931 135.705 118.954 1.00 99.26  ? 107 PHE c N   1 
ATOM   1541 C CA  . PHE B 2 108 ? 124.057 134.265 119.141 1.00 99.26  ? 107 PHE c CA  1 
ATOM   1542 C C   . PHE B 2 108 ? 125.183 133.691 118.295 1.00 99.26  ? 107 PHE c C   1 
ATOM   1543 O O   . PHE B 2 108 ? 125.954 132.851 118.770 1.00 99.26  ? 107 PHE c O   1 
ATOM   1544 C CB  . PHE B 2 108 ? 122.729 133.610 118.781 1.00 99.26  ? 107 PHE c CB  1 
ATOM   1545 C CG  . PHE B 2 108 ? 122.666 132.149 119.059 1.00 99.26  ? 107 PHE c CG  1 
ATOM   1546 C CD1 . PHE B 2 108 ? 122.408 131.690 120.335 1.00 99.26  ? 107 PHE c CD1 1 
ATOM   1547 C CD2 . PHE B 2 108 ? 122.836 131.234 118.039 1.00 99.26  ? 107 PHE c CD2 1 
ATOM   1548 C CE1 . PHE B 2 108 ? 122.326 130.347 120.589 1.00 99.26  ? 107 PHE c CE1 1 
ATOM   1549 C CE2 . PHE B 2 108 ? 122.763 129.890 118.288 1.00 99.26  ? 107 PHE c CE2 1 
ATOM   1550 C CZ  . PHE B 2 108 ? 122.509 129.442 119.567 1.00 99.26  ? 107 PHE c CZ  1 
ATOM   1551 N N   . VAL B 2 109 ? 125.328 134.186 117.064 1.00 97.23  ? 108 VAL c N   1 
ATOM   1552 C CA  . VAL B 2 109 ? 126.319 133.649 116.137 1.00 97.23  ? 108 VAL c CA  1 
ATOM   1553 C C   . VAL B 2 109 ? 127.727 133.971 116.608 1.00 97.23  ? 108 VAL c C   1 
ATOM   1554 O O   . VAL B 2 109 ? 128.590 133.085 116.677 1.00 97.23  ? 108 VAL c O   1 
ATOM   1555 C CB  . VAL B 2 109 ? 126.071 134.191 114.722 1.00 97.23  ? 108 VAL c CB  1 
ATOM   1556 C CG1 . VAL B 2 109 ? 127.170 133.753 113.789 1.00 97.23  ? 108 VAL c CG1 1 
ATOM   1557 C CG2 . VAL B 2 109 ? 124.742 133.711 114.220 1.00 97.23  ? 108 VAL c CG2 1 
ATOM   1558 N N   . ARG B 2 110 ? 127.979 135.236 116.954 1.00 99.61  ? 109 ARG c N   1 
ATOM   1559 C CA  . ARG B 2 110 ? 129.331 135.604 117.351 1.00 99.61  ? 109 ARG c CA  1 
ATOM   1560 C C   . ARG B 2 110 ? 129.699 135.013 118.702 1.00 99.61  ? 109 ARG c C   1 
ATOM   1561 O O   . ARG B 2 110 ? 130.860 134.646 118.905 1.00 99.61  ? 109 ARG c O   1 
ATOM   1562 C CB  . ARG B 2 110 ? 129.522 137.121 117.370 1.00 99.61  ? 109 ARG c CB  1 
ATOM   1563 C CG  . ARG B 2 110 ? 128.740 137.833 118.425 1.00 99.61  ? 109 ARG c CG  1 
ATOM   1564 C CD  . ARG B 2 110 ? 129.213 139.235 118.635 1.00 99.61  ? 109 ARG c CD  1 
ATOM   1565 N NE  . ARG B 2 110 ? 128.428 139.863 119.688 1.00 99.61  ? 109 ARG c NE  1 
ATOM   1566 C CZ  . ARG B 2 110 ? 128.698 139.747 120.981 1.00 99.61  ? 109 ARG c CZ  1 
ATOM   1567 N NH1 . ARG B 2 110 ? 129.744 139.042 121.383 1.00 99.61  ? 109 ARG c NH1 1 
ATOM   1568 N NH2 . ARG B 2 110 ? 127.933 140.351 121.874 1.00 99.61  ? 109 ARG c NH2 1 
ATOM   1569 N N   . THR B 2 111 ? 128.736 134.832 119.610 1.00 101.01 ? 110 THR c N   1 
ATOM   1570 C CA  . THR B 2 111 ? 129.128 134.259 120.886 1.00 101.01 ? 110 THR c CA  1 
ATOM   1571 C C   . THR B 2 111 ? 129.332 132.759 120.765 1.00 101.01 ? 110 THR c C   1 
ATOM   1572 O O   . THR B 2 111 ? 130.228 132.206 121.414 1.00 101.01 ? 110 THR c O   1 
ATOM   1573 C CB  . THR B 2 111 ? 128.096 134.590 121.953 1.00 101.01 ? 110 THR c CB  1 
ATOM   1574 O OG1 . THR B 2 111 ? 127.797 135.985 121.880 1.00 101.01 ? 110 THR c OG1 1 
ATOM   1575 C CG2 . THR B 2 111 ? 128.684 134.344 123.314 1.00 101.01 ? 110 THR c CG2 1 
ATOM   1576 N N   . GLU B 2 112 ? 128.559 132.107 119.889 1.00 97.80  ? 111 GLU c N   1 
ATOM   1577 C CA  . GLU B 2 112 ? 128.771 130.696 119.603 1.00 97.80  ? 111 GLU c CA  1 
ATOM   1578 C C   . GLU B 2 112 ? 130.131 130.459 118.972 1.00 97.80  ? 111 GLU c C   1 
ATOM   1579 O O   . GLU B 2 112 ? 130.850 129.538 119.369 1.00 97.80  ? 111 GLU c O   1 
ATOM   1580 C CB  . GLU B 2 112 ? 127.667 130.187 118.687 1.00 97.80  ? 111 GLU c CB  1 
ATOM   1581 C CG  . GLU B 2 112 ? 127.768 128.725 118.355 1.00 97.80  ? 111 GLU c CG  1 
ATOM   1582 C CD  . GLU B 2 112 ? 126.614 128.256 117.502 1.00 97.80  ? 111 GLU c CD  1 
ATOM   1583 O OE1 . GLU B 2 112 ? 125.741 129.083 117.177 1.00 97.80  ? 111 GLU c OE1 1 
ATOM   1584 O OE2 . GLU B 2 112 ? 126.592 127.068 117.126 1.00 97.80  ? 111 GLU c OE2 1 
ATOM   1585 N N   . LEU B 2 113 ? 130.523 131.314 118.025 1.00 91.26  ? 112 LEU c N   1 
ATOM   1586 C CA  . LEU B 2 113 ? 131.830 131.165 117.395 1.00 91.26  ? 112 LEU c CA  1 
ATOM   1587 C C   . LEU B 2 113 ? 132.959 131.466 118.372 1.00 91.26  ? 112 LEU c C   1 
ATOM   1588 O O   . LEU B 2 113 ? 133.975 130.755 118.398 1.00 91.26  ? 112 LEU c O   1 
ATOM   1589 C CB  . LEU B 2 113 ? 131.925 132.075 116.177 1.00 91.26  ? 112 LEU c CB  1 
ATOM   1590 C CG  . LEU B 2 113 ? 133.232 132.001 115.401 1.00 91.26  ? 112 LEU c CG  1 
ATOM   1591 C CD1 . LEU B 2 113 ? 133.434 130.602 114.888 1.00 91.26  ? 112 LEU c CD1 1 
ATOM   1592 C CD2 . LEU B 2 113 ? 133.202 132.981 114.257 1.00 91.26  ? 112 LEU c CD2 1 
ATOM   1593 N N   . ALA B 2 114 ? 132.777 132.486 119.212 1.00 94.73  ? 113 ALA c N   1 
ATOM   1594 C CA  . ALA B 2 114 ? 133.824 132.888 120.139 1.00 94.73  ? 113 ALA c CA  1 
ATOM   1595 C C   . ALA B 2 114 ? 134.043 131.848 121.225 1.00 94.73  ? 113 ALA c C   1 
ATOM   1596 O O   . ALA B 2 114 ? 135.180 131.619 121.647 1.00 94.73  ? 113 ALA c O   1 
ATOM   1597 C CB  . ALA B 2 114 ? 133.470 134.235 120.756 1.00 94.73  ? 113 ALA c CB  1 
ATOM   1598 N N   . ALA B 2 115 ? 132.978 131.203 121.688 1.00 96.16  ? 114 ALA c N   1 
ATOM   1599 C CA  . ALA B 2 115 ? 133.170 130.144 122.664 1.00 96.16  ? 114 ALA c CA  1 
ATOM   1600 C C   . ALA B 2 115 ? 133.533 128.821 122.017 1.00 96.16  ? 114 ALA c C   1 
ATOM   1601 O O   . ALA B 2 115 ? 134.101 127.957 122.690 1.00 96.16  ? 114 ALA c O   1 
ATOM   1602 C CB  . ALA B 2 115 ? 131.921 129.972 123.520 1.00 96.16  ? 114 ALA c CB  1 
ATOM   1603 N N   . LEU B 2 116 ? 133.234 128.639 120.734 1.00 91.19  ? 115 LEU c N   1 
ATOM   1604 C CA  . LEU B 2 116 ? 133.611 127.406 120.068 1.00 91.19  ? 115 LEU c CA  1 
ATOM   1605 C C   . LEU B 2 116 ? 135.071 127.410 119.649 1.00 91.19  ? 115 LEU c C   1 
ATOM   1606 O O   . LEU B 2 116 ? 135.652 126.337 119.473 1.00 91.19  ? 115 LEU c O   1 
ATOM   1607 C CB  . LEU B 2 116 ? 132.683 127.177 118.872 1.00 91.19  ? 115 LEU c CB  1 
ATOM   1608 C CG  . LEU B 2 116 ? 132.660 125.852 118.113 1.00 91.19  ? 115 LEU c CG  1 
ATOM   1609 C CD1 . LEU B 2 116 ? 131.253 125.531 117.707 1.00 91.19  ? 115 LEU c CD1 1 
ATOM   1610 C CD2 . LEU B 2 116 ? 133.487 125.951 116.867 1.00 91.19  ? 115 LEU c CD2 1 
ATOM   1611 N N   . LEU B 2 117 ? 135.686 128.586 119.519 1.00 91.32  ? 116 LEU c N   1 
ATOM   1612 C CA  . LEU B 2 117 ? 137.118 128.627 119.242 1.00 91.32  ? 116 LEU c CA  1 
ATOM   1613 C C   . LEU B 2 117 ? 137.990 128.224 120.426 1.00 91.32  ? 116 LEU c C   1 
ATOM   1614 O O   . LEU B 2 117 ? 139.208 128.133 120.259 1.00 91.32  ? 116 LEU c O   1 
ATOM   1615 C CB  . LEU B 2 117 ? 137.541 130.015 118.781 1.00 91.32  ? 116 LEU c CB  1 
ATOM   1616 C CG  . LEU B 2 117 ? 137.151 130.424 117.369 1.00 91.32  ? 116 LEU c CG  1 
ATOM   1617 C CD1 . LEU B 2 117 ? 137.498 131.872 117.155 1.00 91.32  ? 116 LEU c CD1 1 
ATOM   1618 C CD2 . LEU B 2 117 ? 137.893 129.571 116.381 1.00 91.32  ? 116 LEU c CD2 1 
ATOM   1619 N N   . ALA B 2 118 ? 137.426 128.004 121.612 1.00 94.91  ? 117 ALA c N   1 
ATOM   1620 C CA  . ALA B 2 118 ? 138.198 127.513 122.745 1.00 94.91  ? 117 ALA c CA  1 
ATOM   1621 C C   . ALA B 2 118 ? 137.766 126.119 123.170 1.00 94.91  ? 117 ALA c C   1 
ATOM   1622 O O   . ALA B 2 118 ? 138.085 125.685 124.280 1.00 94.91  ? 117 ALA c O   1 
ATOM   1623 C CB  . ALA B 2 118 ? 138.097 128.477 123.925 1.00 94.91  ? 117 ALA c CB  1 
ATOM   1624 N N   . SER B 2 119 ? 137.045 125.413 122.308 1.00 94.98  ? 118 SER c N   1 
ATOM   1625 C CA  . SER B 2 119 ? 136.590 124.071 122.607 1.00 94.98  ? 118 SER c CA  1 
ATOM   1626 C C   . SER B 2 119 ? 137.768 123.104 122.603 1.00 94.98  ? 118 SER c C   1 
ATOM   1627 O O   . SER B 2 119 ? 138.811 123.392 122.019 1.00 94.98  ? 118 SER c O   1 
ATOM   1628 C CB  . SER B 2 119 ? 135.561 123.633 121.571 1.00 94.98  ? 118 SER c CB  1 
ATOM   1629 O OG  . SER B 2 119 ? 136.190 123.408 120.324 1.00 94.98  ? 118 SER c OG  1 
ATOM   1630 N N   . PRO B 2 120 ? 137.623 121.928 123.224 1.00 97.97  ? 119 PRO c N   1 
ATOM   1631 C CA  . PRO B 2 120 ? 138.640 120.883 123.042 1.00 97.97  ? 119 PRO c CA  1 
ATOM   1632 C C   . PRO B 2 120 ? 138.646 120.253 121.661 1.00 97.97  ? 119 PRO c C   1 
ATOM   1633 O O   . PRO B 2 120 ? 139.483 119.383 121.406 1.00 97.97  ? 119 PRO c O   1 
ATOM   1634 C CB  . PRO B 2 120 ? 138.277 119.849 124.113 1.00 97.97  ? 119 PRO c CB  1 
ATOM   1635 C CG  . PRO B 2 120 ? 136.854 120.081 124.397 1.00 97.97  ? 119 PRO c CG  1 
ATOM   1636 C CD  . PRO B 2 120 ? 136.661 121.558 124.274 1.00 97.97  ? 119 PRO c CD  1 
ATOM   1637 N N   . LEU B 2 121 ? 137.744 120.649 120.766 1.00 96.82  ? 120 LEU c N   1 
ATOM   1638 C CA  . LEU B 2 121 ? 137.826 120.213 119.381 1.00 96.82  ? 120 LEU c CA  1 
ATOM   1639 C C   . LEU B 2 121 ? 138.853 121.034 118.613 1.00 96.82  ? 120 LEU c C   1 
ATOM   1640 O O   . LEU B 2 121 ? 139.796 120.479 118.042 1.00 96.82  ? 120 LEU c O   1 
ATOM   1641 C CB  . LEU B 2 121 ? 136.442 120.303 118.736 1.00 96.82  ? 120 LEU c CB  1 
ATOM   1642 C CG  . LEU B 2 121 ? 136.132 119.723 117.352 1.00 96.82  ? 120 LEU c CG  1 
ATOM   1643 C CD1 . LEU B 2 121 ? 136.421 120.682 116.208 1.00 96.82  ? 120 LEU c CD1 1 
ATOM   1644 C CD2 . LEU B 2 121 ? 136.900 118.427 117.155 1.00 96.82  ? 120 LEU c CD2 1 
ATOM   1645 N N   . LEU B 2 122 ? 138.691 122.356 118.591 1.00 96.99  ? 121 LEU c N   1 
ATOM   1646 C CA  . LEU B 2 122 ? 139.521 123.182 117.726 1.00 96.99  ? 121 LEU c CA  1 
ATOM   1647 C C   . LEU B 2 122 ? 140.934 123.386 118.240 1.00 96.99  ? 121 LEU c C   1 
ATOM   1648 O O   . LEU B 2 122 ? 141.820 123.684 117.435 1.00 96.99  ? 121 LEU c O   1 
ATOM   1649 C CB  . LEU B 2 122 ? 138.886 124.545 117.504 1.00 96.99  ? 121 LEU c CB  1 
ATOM   1650 C CG  . LEU B 2 122 ? 137.646 124.530 116.634 1.00 96.99  ? 121 LEU c CG  1 
ATOM   1651 C CD1 . LEU B 2 122 ? 137.152 125.931 116.526 1.00 96.99  ? 121 LEU c CD1 1 
ATOM   1652 C CD2 . LEU B 2 122 ? 137.978 123.994 115.272 1.00 96.99  ? 121 LEU c CD2 1 
ATOM   1653 N N   . ILE B 2 123 ? 141.177 123.231 119.544 1.00 104.53 ? 122 ILE c N   1 
ATOM   1654 C CA  . ILE B 2 123 ? 142.546 123.332 120.033 1.00 104.53 ? 122 ILE c CA  1 
ATOM   1655 C C   . ILE B 2 123 ? 143.369 122.140 119.578 1.00 104.53 ? 122 ILE c C   1 
ATOM   1656 O O   . ILE B 2 123 ? 144.599 122.215 119.547 1.00 104.53 ? 122 ILE c O   1 
ATOM   1657 C CB  . ILE B 2 123 ? 142.568 123.495 121.567 1.00 104.53 ? 122 ILE c CB  1 
ATOM   1658 C CG1 . ILE B 2 123 ? 141.948 122.297 122.289 1.00 104.53 ? 122 ILE c CG1 1 
ATOM   1659 C CG2 . ILE B 2 123 ? 141.806 124.727 121.965 1.00 104.53 ? 122 ILE c CG2 1 
ATOM   1660 C CD1 . ILE B 2 123 ? 142.929 121.276 122.862 1.00 104.53 ? 122 ILE c CD1 1 
ATOM   1661 N N   . ASP B 2 124 ? 142.718 121.035 119.233 1.00 109.61 ? 123 ASP c N   1 
ATOM   1662 C CA  . ASP B 2 124 ? 143.383 119.923 118.582 1.00 109.61 ? 123 ASP c CA  1 
ATOM   1663 C C   . ASP B 2 124 ? 143.365 120.050 117.068 1.00 109.61 ? 123 ASP c C   1 
ATOM   1664 O O   . ASP B 2 124 ? 144.238 119.488 116.397 1.00 109.61 ? 123 ASP c O   1 
ATOM   1665 C CB  . ASP B 2 124 ? 142.724 118.610 119.014 1.00 109.61 ? 123 ASP c CB  1 
ATOM   1666 C CG  . ASP B 2 124 ? 143.464 117.391 118.515 1.00 109.61 ? 123 ASP c CG  1 
ATOM   1667 O OD1 . ASP B 2 124 ? 144.571 117.118 119.022 1.00 109.61 ? 123 ASP c OD1 1 
ATOM   1668 O OD2 . ASP B 2 124 ? 142.934 116.700 117.623 1.00 109.61 ? 123 ASP c OD2 1 
ATOM   1669 N N   . ALA B 2 125 ? 142.416 120.798 116.517 1.00 102.48 ? 124 ALA c N   1 
ATOM   1670 C CA  . ALA B 2 125 ? 142.310 120.938 115.075 1.00 102.48 ? 124 ALA c CA  1 
ATOM   1671 C C   . ALA B 2 125 ? 143.131 122.088 114.520 1.00 102.48 ? 124 ALA c C   1 
ATOM   1672 O O   . ALA B 2 125 ? 143.234 122.214 113.298 1.00 102.48 ? 124 ALA c O   1 
ATOM   1673 C CB  . ALA B 2 125 ? 140.848 121.119 114.664 1.00 102.48 ? 124 ALA c CB  1 
ATOM   1674 N N   . ILE B 2 126 ? 143.702 122.932 115.369 1.00 102.32 ? 125 ILE c N   1 
ATOM   1675 C CA  . ILE B 2 126 ? 144.550 124.031 114.931 1.00 102.32 ? 125 ILE c CA  1 
ATOM   1676 C C   . ILE B 2 126 ? 145.986 123.845 115.399 1.00 102.32 ? 125 ILE c C   1 
ATOM   1677 O O   . ILE B 2 126 ? 146.923 123.935 114.606 1.00 102.32 ? 125 ILE c O   1 
ATOM   1678 C CB  . ILE B 2 126 ? 143.985 125.390 115.397 1.00 102.32 ? 125 ILE c CB  1 
ATOM   1679 C CG1 . ILE B 2 126 ? 142.685 125.699 114.665 1.00 102.32 ? 125 ILE c CG1 1 
ATOM   1680 C CG2 . ILE B 2 126 ? 144.980 126.500 115.161 1.00 102.32 ? 125 ILE c CG2 1 
ATOM   1681 C CD1 . ILE B 2 126 ? 141.979 126.916 115.181 1.00 102.32 ? 125 ILE c CD1 1 
ATOM   1682 N N   . ASP B 2 127 ? 146.176 123.547 116.680 1.00 109.37 ? 126 ASP c N   1 
ATOM   1683 C CA  . ASP B 2 127 ? 147.521 123.487 117.229 1.00 109.37 ? 126 ASP c CA  1 
ATOM   1684 C C   . ASP B 2 127 ? 148.272 122.229 116.828 1.00 109.37 ? 126 ASP c C   1 
ATOM   1685 O O   . ASP B 2 127 ? 149.493 122.180 116.986 1.00 109.37 ? 126 ASP c O   1 
ATOM   1686 C CB  . ASP B 2 127 ? 147.456 123.592 118.746 1.00 109.37 ? 126 ASP c CB  1 
ATOM   1687 C CG  . ASP B 2 127 ? 146.846 124.894 119.195 1.00 109.37 ? 126 ASP c CG  1 
ATOM   1688 O OD1 . ASP B 2 127 ? 146.949 125.867 118.428 1.00 109.37 ? 126 ASP c OD1 1 
ATOM   1689 O OD2 . ASP B 2 127 ? 146.256 124.941 120.293 1.00 109.37 ? 126 ASP c OD2 1 
ATOM   1690 N N   . GLN B 2 128 ? 147.577 121.214 116.330 1.00 112.42 ? 127 GLN c N   1 
ATOM   1691 C CA  . GLN B 2 128 ? 148.220 120.014 115.823 1.00 112.42 ? 127 GLN c CA  1 
ATOM   1692 C C   . GLN B 2 128 ? 147.692 119.619 114.455 1.00 112.42 ? 127 GLN c C   1 
ATOM   1693 O O   . GLN B 2 128 ? 148.191 118.647 113.876 1.00 112.42 ? 127 GLN c O   1 
ATOM   1694 C CB  . GLN B 2 128 ? 148.038 118.841 116.799 1.00 112.42 ? 127 GLN c CB  1 
ATOM   1695 C CG  . GLN B 2 128 ? 148.819 118.964 118.100 1.00 112.42 ? 127 GLN c CG  1 
ATOM   1696 C CD  . GLN B 2 128 ? 148.118 119.827 119.122 1.00 112.42 ? 127 GLN c CD  1 
ATOM   1697 O OE1 . GLN B 2 128 ? 146.929 120.106 118.997 1.00 112.42 ? 127 GLN c OE1 1 
ATOM   1698 N NE2 . GLN B 2 128 ? 148.854 120.266 120.132 1.00 112.42 ? 127 GLN c NE2 1 
ATOM   1699 N N   . LEU B 2 129 ? 146.691 120.341 113.945 1.00 102.12 ? 128 LEU c N   1 
ATOM   1700 C CA  . LEU B 2 129 ? 146.102 120.157 112.617 1.00 102.12 ? 128 LEU c CA  1 
ATOM   1701 C C   . LEU B 2 129 ? 145.539 118.754 112.429 1.00 102.12 ? 128 LEU c C   1 
ATOM   1702 O O   . LEU B 2 129 ? 145.625 118.174 111.347 1.00 102.12 ? 128 LEU c O   1 
ATOM   1703 C CB  . LEU B 2 129 ? 147.086 120.486 111.497 1.00 102.12 ? 128 LEU c CB  1 
ATOM   1704 C CG  . LEU B 2 129 ? 147.389 121.964 111.294 1.00 102.12 ? 128 LEU c CG  1 
ATOM   1705 C CD1 . LEU B 2 129 ? 148.568 122.418 112.130 1.00 102.12 ? 128 LEU c CD1 1 
ATOM   1706 C CD2 . LEU B 2 129 ? 147.576 122.258 109.845 1.00 102.12 ? 128 LEU c CD2 1 
ATOM   1707 N N   . ASN B 2 130 ? 144.971 118.213 113.467 1.00 106.70 ? 129 ASN c N   1 
ATOM   1708 C CA  . ASN B 2 130 ? 144.371 116.905 113.296 1.00 106.70 ? 129 ASN c CA  1 
ATOM   1709 C C   . ASN B 2 130 ? 143.007 117.041 112.630 1.00 106.70 ? 129 ASN c C   1 
ATOM   1710 O O   . ASN B 2 130 ? 142.244 117.950 112.960 1.00 106.70 ? 129 ASN c O   1 
ATOM   1711 C CB  . ASN B 2 130 ? 144.222 116.209 114.637 1.00 106.70 ? 129 ASN c CB  1 
ATOM   1712 C CG  . ASN B 2 130 ? 145.551 115.811 115.232 1.00 106.70 ? 129 ASN c CG  1 
ATOM   1713 O OD1 . ASN B 2 130 ? 146.415 115.265 114.545 1.00 106.70 ? 129 ASN c OD1 1 
ATOM   1714 N ND2 . ASN B 2 130 ? 145.733 116.104 116.512 1.00 106.70 ? 129 ASN c ND2 1 
ATOM   1715 N N   . PRO B 2 131 ? 142.682 116.168 111.694 1.00 106.88 ? 130 PRO c N   1 
ATOM   1716 C CA  . PRO B 2 131 ? 141.315 116.127 111.162 1.00 106.88 ? 130 PRO c CA  1 
ATOM   1717 C C   . PRO B 2 131 ? 140.341 115.498 112.143 1.00 106.88 ? 130 PRO c C   1 
ATOM   1718 O O   . PRO B 2 131 ? 140.699 115.183 113.281 1.00 106.88 ? 130 PRO c O   1 
ATOM   1719 C CB  . PRO B 2 131 ? 141.458 115.268 109.901 1.00 106.88 ? 130 PRO c CB  1 
ATOM   1720 C CG  . PRO B 2 131 ? 142.909 115.289 109.571 1.00 106.88 ? 130 PRO c CG  1 
ATOM   1721 C CD  . PRO B 2 131 ? 143.611 115.368 110.882 1.00 106.88 ? 130 PRO c CD  1 
ATOM   1722 N N   . ALA B 2 132 ? 139.103 115.299 111.721 1.00 104.28 ? 131 ALA c N   1 
ATOM   1723 C CA  . ALA B 2 132 ? 138.158 114.599 112.574 1.00 104.28 ? 131 ALA c CA  1 
ATOM   1724 C C   . ALA B 2 132 ? 137.772 113.256 111.967 1.00 104.28 ? 131 ALA c C   1 
ATOM   1725 O O   . ALA B 2 132 ? 138.132 112.203 112.492 1.00 104.28 ? 131 ALA c O   1 
ATOM   1726 C CB  . ALA B 2 132 ? 136.939 115.445 112.809 1.00 104.28 ? 131 ALA c CB  1 
ATOM   1727 N N   . ALA C 2 2   ? 140.682 115.327 117.675 1.00 112.87 ? 1   ALA C N   1 
ATOM   1728 C CA  . ALA C 2 2   ? 140.850 114.154 116.830 1.00 112.87 ? 1   ALA C CA  1 
ATOM   1729 C C   . ALA C 2 2   ? 139.565 113.342 116.787 1.00 112.87 ? 1   ALA C C   1 
ATOM   1730 O O   . ALA C 2 2   ? 138.756 113.492 115.873 1.00 112.87 ? 1   ALA C O   1 
ATOM   1731 C CB  . ALA C 2 2   ? 141.999 113.302 117.328 1.00 112.87 ? 1   ALA C CB  1 
ATOM   1732 N N   . LYS C 2 3   ? 139.390 112.475 117.778 1.00 113.32 ? 2   LYS C N   1 
ATOM   1733 C CA  . LYS C 2 3   ? 138.157 111.708 117.924 1.00 113.32 ? 2   LYS C CA  1 
ATOM   1734 C C   . LYS C 2 3   ? 137.060 112.670 118.347 1.00 113.32 ? 2   LYS C C   1 
ATOM   1735 O O   . LYS C 2 3   ? 137.006 113.101 119.499 1.00 113.32 ? 2   LYS C O   1 
ATOM   1736 C CB  . LYS C 2 3   ? 138.341 110.595 118.946 1.00 113.32 ? 2   LYS C CB  1 
ATOM   1737 C CG  . LYS C 2 3   ? 137.133 109.699 119.119 1.00 113.32 ? 2   LYS C CG  1 
ATOM   1738 C CD  . LYS C 2 3   ? 136.894 108.865 117.878 1.00 113.32 ? 2   LYS C CD  1 
ATOM   1739 C CE  . LYS C 2 3   ? 135.695 107.950 118.053 1.00 113.32 ? 2   LYS C CE  1 
ATOM   1740 N NZ  . LYS C 2 3   ? 135.940 106.913 119.090 1.00 113.32 ? 2   LYS C NZ  1 
ATOM   1741 N N   . LEU C 2 4   ? 136.189 113.025 117.409 1.00 104.64 ? 3   LEU C N   1 
ATOM   1742 C CA  . LEU C 2 4   ? 135.182 114.042 117.666 1.00 104.64 ? 3   LEU C CA  1 
ATOM   1743 C C   . LEU C 2 4   ? 134.067 113.480 118.536 1.00 104.64 ? 3   LEU C C   1 
ATOM   1744 O O   . LEU C 2 4   ? 133.651 112.330 118.377 1.00 104.64 ? 3   LEU C O   1 
ATOM   1745 C CB  . LEU C 2 4   ? 134.621 114.593 116.353 1.00 104.64 ? 3   LEU C CB  1 
ATOM   1746 C CG  . LEU C 2 4   ? 133.617 113.846 115.475 1.00 104.64 ? 3   LEU C CG  1 
ATOM   1747 C CD1 . LEU C 2 4   ? 133.020 114.822 114.487 1.00 104.64 ? 3   LEU C CD1 1 
ATOM   1748 C CD2 . LEU C 2 4   ? 134.235 112.675 114.738 1.00 104.64 ? 3   LEU C CD2 1 
ATOM   1749 N N   . GLU C 2 5   ? 133.614 114.290 119.490 1.00 103.71 ? 4   GLU C N   1 
ATOM   1750 C CA  . GLU C 2 5   ? 132.619 113.849 120.458 1.00 103.71 ? 4   GLU C CA  1 
ATOM   1751 C C   . GLU C 2 5   ? 131.507 114.873 120.601 1.00 103.71 ? 4   GLU C C   1 
ATOM   1752 O O   . GLU C 2 5   ? 131.449 115.846 119.845 1.00 103.71 ? 4   GLU C O   1 
ATOM   1753 C CB  . GLU C 2 5   ? 133.265 113.597 121.819 1.00 103.71 ? 4   GLU C CB  1 
ATOM   1754 C CG  . GLU C 2 5   ? 134.182 112.392 121.870 1.00 103.71 ? 4   GLU C CG  1 
ATOM   1755 C CD  . GLU C 2 5   ? 134.818 112.209 123.233 1.00 103.71 ? 4   GLU C CD  1 
ATOM   1756 O OE1 . GLU C 2 5   ? 134.651 113.100 124.091 1.00 103.71 ? 4   GLU C OE1 1 
ATOM   1757 O OE2 . GLU C 2 5   ? 135.484 111.175 123.446 1.00 103.71 ? 4   GLU C OE2 1 
ATOM   1758 N N   . THR C 2 6   ? 130.627 114.667 121.578 1.00 98.95  ? 5   THR C N   1 
ATOM   1759 C CA  . THR C 2 6   ? 129.504 115.569 121.787 1.00 98.95  ? 5   THR C CA  1 
ATOM   1760 C C   . THR C 2 6   ? 129.980 116.866 122.418 1.00 98.95  ? 5   THR C C   1 
ATOM   1761 O O   . THR C 2 6   ? 130.043 116.982 123.645 1.00 98.95  ? 5   THR C O   1 
ATOM   1762 C CB  . THR C 2 6   ? 128.444 114.919 122.670 1.00 98.95  ? 5   THR C CB  1 
ATOM   1763 O OG1 . THR C 2 6   ? 128.993 114.682 123.969 1.00 98.95  ? 5   THR C OG1 1 
ATOM   1764 C CG2 . THR C 2 6   ? 128.004 113.598 122.076 1.00 98.95  ? 5   THR C CG2 1 
ATOM   1765 N N   . VAL C 2 7   ? 130.321 117.845 121.585 1.00 90.01  ? 6   VAL C N   1 
ATOM   1766 C CA  . VAL C 2 7   ? 130.806 119.119 122.089 1.00 90.01  ? 6   VAL C CA  1 
ATOM   1767 C C   . VAL C 2 7   ? 129.640 119.924 122.637 1.00 90.01  ? 6   VAL C C   1 
ATOM   1768 O O   . VAL C 2 7   ? 128.641 120.154 121.944 1.00 90.01  ? 6   VAL C O   1 
ATOM   1769 C CB  . VAL C 2 7   ? 131.538 119.887 120.983 1.00 90.01  ? 6   VAL C CB  1 
ATOM   1770 C CG1 . VAL C 2 7   ? 131.967 121.248 121.484 1.00 90.01  ? 6   VAL C CG1 1 
ATOM   1771 C CG2 . VAL C 2 7   ? 132.731 119.093 120.508 1.00 90.01  ? 6   VAL C CG2 1 
ATOM   1772 N N   . THR C 2 8   ? 129.755 120.348 123.888 1.00 96.38  ? 7   THR C N   1 
ATOM   1773 C CA  . THR C 2 8   ? 128.750 121.183 124.523 1.00 96.38  ? 7   THR C CA  1 
ATOM   1774 C C   . THR C 2 8   ? 129.361 122.539 124.822 1.00 96.38  ? 7   THR C C   1 
ATOM   1775 O O   . THR C 2 8   ? 130.435 122.619 125.422 1.00 96.38  ? 7   THR C O   1 
ATOM   1776 C CB  . THR C 2 8   ? 128.239 120.560 125.812 1.00 96.38  ? 7   THR C CB  1 
ATOM   1777 O OG1 . THR C 2 8   ? 129.307 120.508 126.760 1.00 96.38  ? 7   THR C OG1 1 
ATOM   1778 C CG2 . THR C 2 8   ? 127.748 119.154 125.551 1.00 96.38  ? 7   THR C CG2 1 
ATOM   1779 N N   . LEU C 2 9   ? 128.674 123.593 124.411 1.00 95.85  ? 8   LEU C N   1 
ATOM   1780 C CA  . LEU C 2 9   ? 129.107 124.951 124.691 1.00 95.85  ? 8   LEU C CA  1 
ATOM   1781 C C   . LEU C 2 9   ? 128.567 125.357 126.058 1.00 95.85  ? 8   LEU C C   1 
ATOM   1782 O O   . LEU C 2 9   ? 128.047 124.534 126.815 1.00 95.85  ? 8   LEU C O   1 
ATOM   1783 C CB  . LEU C 2 9   ? 128.646 125.897 123.589 1.00 95.85  ? 8   LEU C CB  1 
ATOM   1784 C CG  . LEU C 2 9   ? 129.501 126.034 122.326 1.00 95.85  ? 8   LEU C CG  1 
ATOM   1785 C CD1 . LEU C 2 9   ? 130.901 126.463 122.702 1.00 95.85  ? 8   LEU C CD1 1 
ATOM   1786 C CD2 . LEU C 2 9   ? 129.531 124.792 121.453 1.00 95.85  ? 8   LEU C CD2 1 
ATOM   1787 N N   . GLY C 2 10  ? 128.678 126.635 126.395 1.00 104.64 ? 9   GLY C N   1 
ATOM   1788 C CA  . GLY C 2 10  ? 128.134 127.094 127.654 1.00 104.64 ? 9   GLY C CA  1 
ATOM   1789 C C   . GLY C 2 10  ? 128.060 128.597 127.788 1.00 104.64 ? 9   GLY C C   1 
ATOM   1790 O O   . GLY C 2 10  ? 129.045 129.292 127.520 1.00 104.64 ? 9   GLY C O   1 
ATOM   1791 N N   . ASN C 2 11  ? 126.886 129.088 128.199 1.00 112.42 ? 10  ASN C N   1 
ATOM   1792 C CA  . ASN C 2 11  ? 126.629 130.482 128.571 1.00 112.42 ? 10  ASN C CA  1 
ATOM   1793 C C   . ASN C 2 11  ? 126.928 131.433 127.410 1.00 112.42 ? 10  ASN C C   1 
ATOM   1794 O O   . ASN C 2 11  ? 127.828 132.270 127.466 1.00 112.42 ? 10  ASN C O   1 
ATOM   1795 C CB  . ASN C 2 11  ? 127.435 130.857 129.817 1.00 112.42 ? 10  ASN C CB  1 
ATOM   1796 C CG  . ASN C 2 11  ? 127.101 129.983 130.993 1.00 112.42 ? 10  ASN C CG  1 
ATOM   1797 O OD1 . ASN C 2 11  ? 127.923 129.187 131.437 1.00 112.42 ? 10  ASN C OD1 1 
ATOM   1798 N ND2 . ASN C 2 11  ? 125.886 130.117 131.503 1.00 112.42 ? 10  ASN C ND2 1 
ATOM   1799 N N   . ILE C 2 12  ? 126.150 131.274 126.345 1.00 110.01 ? 11  ILE C N   1 
ATOM   1800 C CA  . ILE C 2 12  ? 126.425 131.968 125.096 1.00 110.01 ? 11  ILE C CA  1 
ATOM   1801 C C   . ILE C 2 12  ? 125.200 132.733 124.619 1.00 110.01 ? 11  ILE C C   1 
ATOM   1802 O O   . ILE C 2 12  ? 124.074 132.229 124.677 1.00 110.01 ? 11  ILE C O   1 
ATOM   1803 C CB  . ILE C 2 12  ? 126.952 131.001 124.018 1.00 110.01 ? 11  ILE C CB  1 
ATOM   1804 C CG1 . ILE C 2 12  ? 126.116 129.732 123.911 1.00 110.01 ? 11  ILE C CG1 1 
ATOM   1805 C CG2 . ILE C 2 12  ? 128.373 130.624 124.314 1.00 110.01 ? 11  ILE C CG2 1 
ATOM   1806 C CD1 . ILE C 2 12  ? 125.084 129.740 122.823 1.00 110.01 ? 11  ILE C CD1 1 
ATOM   1807 N N   . GLY C 2 13  ? 125.428 133.973 124.205 1.00 111.33 ? 12  GLY C N   1 
ATOM   1808 C CA  . GLY C 2 13  ? 124.504 134.796 123.453 1.00 111.33 ? 12  GLY C CA  1 
ATOM   1809 C C   . GLY C 2 13  ? 123.782 135.824 124.295 1.00 111.33 ? 12  GLY C C   1 
ATOM   1810 O O   . GLY C 2 13  ? 122.738 135.536 124.883 1.00 111.33 ? 12  GLY C O   1 
ATOM   1811 N N   . LYS C 2 14  ? 124.367 137.024 124.378 1.00 109.39 ? 13  LYS C N   1 
ATOM   1812 C CA  . LYS C 2 14  ? 123.793 138.284 124.858 1.00 109.39 ? 13  LYS C CA  1 
ATOM   1813 C C   . LYS C 2 14  ? 123.487 138.307 126.361 1.00 109.39 ? 13  LYS C C   1 
ATOM   1814 O O   . LYS C 2 14  ? 123.428 139.381 126.969 1.00 109.39 ? 13  LYS C O   1 
ATOM   1815 C CB  . LYS C 2 14  ? 122.542 138.607 124.019 1.00 109.39 ? 13  LYS C CB  1 
ATOM   1816 C CG  . LYS C 2 14  ? 121.819 139.915 124.314 1.00 109.39 ? 13  LYS C CG  1 
ATOM   1817 C CD  . LYS C 2 14  ? 122.718 141.111 124.114 1.00 109.39 ? 13  LYS C CD  1 
ATOM   1818 C CE  . LYS C 2 14  ? 123.054 141.298 122.655 1.00 109.39 ? 13  LYS C CE  1 
ATOM   1819 N NZ  . LYS C 2 14  ? 121.851 141.697 121.878 1.00 109.39 ? 13  LYS C NZ  1 
ATOM   1820 N N   . ASP C 2 15  ? 123.405 137.150 127.010 1.00 118.34 ? 14  ASP C N   1 
ATOM   1821 C CA  . ASP C 2 15  ? 123.227 137.127 128.453 1.00 118.34 ? 14  ASP C CA  1 
ATOM   1822 C C   . ASP C 2 15  ? 123.997 136.027 129.158 1.00 118.34 ? 14  ASP C C   1 
ATOM   1823 O O   . ASP C 2 15  ? 124.094 136.066 130.387 1.00 118.34 ? 14  ASP C O   1 
ATOM   1824 C CB  . ASP C 2 15  ? 121.734 137.029 128.809 1.00 118.34 ? 14  ASP C CB  1 
ATOM   1825 C CG  . ASP C 2 15  ? 121.049 135.812 128.206 1.00 118.34 ? 14  ASP C CG  1 
ATOM   1826 O OD1 . ASP C 2 15  ? 121.689 135.023 127.484 1.00 118.34 ? 14  ASP C OD1 1 
ATOM   1827 O OD2 . ASP C 2 15  ? 119.836 135.650 128.450 1.00 118.34 ? 14  ASP C OD2 1 
ATOM   1828 N N   . GLY C 2 16  ? 124.532 135.046 128.441 1.00 117.86 ? 15  GLY C N   1 
ATOM   1829 C CA  . GLY C 2 16  ? 125.142 133.918 129.104 1.00 117.86 ? 15  GLY C CA  1 
ATOM   1830 C C   . GLY C 2 16  ? 124.159 132.947 129.706 1.00 117.86 ? 15  GLY C C   1 
ATOM   1831 O O   . GLY C 2 16  ? 124.519 132.203 130.618 1.00 117.86 ? 15  GLY C O   1 
ATOM   1832 N N   . LYS C 2 17  ? 122.919 132.933 129.228 1.00 120.82 ? 16  LYS C N   1 
ATOM   1833 C CA  . LYS C 2 17  ? 121.898 132.052 129.768 1.00 120.82 ? 16  LYS C CA  1 
ATOM   1834 C C   . LYS C 2 17  ? 121.496 130.939 128.821 1.00 120.82 ? 16  LYS C C   1 
ATOM   1835 O O   . LYS C 2 17  ? 120.596 130.164 129.153 1.00 120.82 ? 16  LYS C O   1 
ATOM   1836 C CB  . LYS C 2 17  ? 120.648 132.846 130.141 1.00 120.82 ? 16  LYS C CB  1 
ATOM   1837 C CG  . LYS C 2 17  ? 120.803 133.758 131.323 1.00 120.82 ? 16  LYS C CG  1 
ATOM   1838 C CD  . LYS C 2 17  ? 119.468 134.399 131.622 1.00 120.82 ? 16  LYS C CD  1 
ATOM   1839 C CE  . LYS C 2 17  ? 119.553 135.330 132.797 1.00 120.82 ? 16  LYS C CE  1 
ATOM   1840 N NZ  . LYS C 2 17  ? 118.226 135.939 133.082 1.00 120.82 ? 16  LYS C NZ  1 
ATOM   1841 N N   . GLN C 2 18  ? 122.104 130.844 127.652 1.00 113.60 ? 17  GLN C N   1 
ATOM   1842 C CA  . GLN C 2 18  ? 121.755 129.808 126.697 1.00 113.60 ? 17  GLN C CA  1 
ATOM   1843 C C   . GLN C 2 18  ? 122.925 128.852 126.559 1.00 113.60 ? 17  GLN C C   1 
ATOM   1844 O O   . GLN C 2 18  ? 124.072 129.286 126.427 1.00 113.60 ? 17  GLN C O   1 
ATOM   1845 C CB  . GLN C 2 18  ? 121.394 130.409 125.343 1.00 113.60 ? 17  GLN C CB  1 
ATOM   1846 C CG  . GLN C 2 18  ? 120.150 131.259 125.376 1.00 113.60 ? 17  GLN C CG  1 
ATOM   1847 C CD  . GLN C 2 18  ? 119.824 131.846 124.027 1.00 113.60 ? 17  GLN C CD  1 
ATOM   1848 O OE1 . GLN C 2 18  ? 120.560 131.653 123.061 1.00 113.60 ? 17  GLN C OE1 1 
ATOM   1849 N NE2 . GLN C 2 18  ? 118.719 132.573 123.950 1.00 113.60 ? 17  GLN C NE2 1 
ATOM   1850 N N   . THR C 2 19  ? 122.637 127.564 126.624 1.00 107.73 ? 18  THR C N   1 
ATOM   1851 C CA  . THR C 2 19  ? 123.624 126.534 126.369 1.00 107.73 ? 18  THR C CA  1 
ATOM   1852 C C   . THR C 2 19  ? 123.337 125.894 125.022 1.00 107.73 ? 18  THR C C   1 
ATOM   1853 O O   . THR C 2 19  ? 122.328 126.174 124.373 1.00 107.73 ? 18  THR C O   1 
ATOM   1854 C CB  . THR C 2 19  ? 123.624 125.484 127.475 1.00 107.73 ? 18  THR C CB  1 
ATOM   1855 O OG1 . THR C 2 19  ? 124.721 124.588 127.272 1.00 107.73 ? 18  THR C OG1 1 
ATOM   1856 C CG2 . THR C 2 19  ? 122.335 124.699 127.445 1.00 107.73 ? 18  THR C CG2 1 
ATOM   1857 N N   . LEU C 2 20  ? 124.236 125.014 124.606 1.00 99.43  ? 19  LEU C N   1 
ATOM   1858 C CA  . LEU C 2 20  ? 124.108 124.389 123.304 1.00 99.43  ? 19  LEU C CA  1 
ATOM   1859 C C   . LEU C 2 20  ? 124.837 123.060 123.341 1.00 99.43  ? 19  LEU C C   1 
ATOM   1860 O O   . LEU C 2 20  ? 125.927 122.966 123.903 1.00 99.43  ? 19  LEU C O   1 
ATOM   1861 C CB  . LEU C 2 20  ? 124.682 125.289 122.211 1.00 99.43  ? 19  LEU C CB  1 
ATOM   1862 C CG  . LEU C 2 20  ? 124.513 124.777 120.791 1.00 99.43  ? 19  LEU C CG  1 
ATOM   1863 C CD1 . LEU C 2 20  ? 123.043 124.635 120.492 1.00 99.43  ? 19  LEU C CD1 1 
ATOM   1864 C CD2 . LEU C 2 20  ? 125.156 125.734 119.828 1.00 99.43  ? 19  LEU C CD2 1 
ATOM   1865 N N   . VAL C 2 21  ? 124.225 122.035 122.767 1.00 91.12  ? 20  VAL C N   1 
ATOM   1866 C CA  . VAL C 2 21  ? 124.882 120.749 122.620 1.00 91.12  ? 20  VAL C CA  1 
ATOM   1867 C C   . VAL C 2 21  ? 125.008 120.453 121.138 1.00 91.12  ? 20  VAL C C   1 
ATOM   1868 O O   . VAL C 2 21  ? 124.240 120.948 120.312 1.00 91.12  ? 20  VAL C O   1 
ATOM   1869 C CB  . VAL C 2 21  ? 124.133 119.621 123.345 1.00 91.12  ? 20  VAL C CB  1 
ATOM   1870 C CG1 . VAL C 2 21  ? 124.126 119.887 124.822 1.00 91.12  ? 20  VAL C CG1 1 
ATOM   1871 C CG2 . VAL C 2 21  ? 122.715 119.516 122.836 1.00 91.12  ? 20  VAL C CG2 1 
ATOM   1872 N N   . LEU C 2 22  ? 126.010 119.656 120.798 1.00 93.62  ? 21  LEU C N   1 
ATOM   1873 C CA  . LEU C 2 22  ? 126.203 119.234 119.427 1.00 93.62  ? 21  LEU C CA  1 
ATOM   1874 C C   . LEU C 2 22  ? 126.412 117.732 119.389 1.00 93.62  ? 21  LEU C C   1 
ATOM   1875 O O   . LEU C 2 22  ? 126.894 117.123 120.345 1.00 93.62  ? 21  LEU C O   1 
ATOM   1876 C CB  . LEU C 2 22  ? 127.392 119.944 118.782 1.00 93.62  ? 21  LEU C CB  1 
ATOM   1877 C CG  . LEU C 2 22  ? 127.217 121.442 118.571 1.00 93.62  ? 21  LEU C CG  1 
ATOM   1878 C CD1 . LEU C 2 22  ? 128.490 122.056 118.046 1.00 93.62  ? 21  LEU C CD1 1 
ATOM   1879 C CD2 . LEU C 2 22  ? 126.076 121.685 117.617 1.00 93.62  ? 21  LEU C CD2 1 
ATOM   1880 N N   . ASN C 2 23  ? 126.039 117.140 118.267 1.00 93.57  ? 22  ASN C N   1 
ATOM   1881 C CA  . ASN C 2 23  ? 126.276 115.737 118.035 1.00 93.57  ? 22  ASN C CA  1 
ATOM   1882 C C   . ASN C 2 23  ? 127.005 115.593 116.708 1.00 93.57  ? 22  ASN C C   1 
ATOM   1883 O O   . ASN C 2 23  ? 126.758 116.375 115.781 1.00 93.57  ? 22  ASN C O   1 
ATOM   1884 C CB  . ASN C 2 23  ? 124.962 114.956 118.007 1.00 93.57  ? 22  ASN C CB  1 
ATOM   1885 C CG  . ASN C 2 23  ? 124.210 115.054 119.309 1.00 93.57  ? 22  ASN C CG  1 
ATOM   1886 O OD1 . ASN C 2 23  ? 123.098 115.572 119.359 1.00 93.57  ? 22  ASN C OD1 1 
ATOM   1887 N ND2 . ASN C 2 23  ? 124.821 114.573 120.379 1.00 93.57  ? 22  ASN C ND2 1 
ATOM   1888 N N   . PRO C 2 24  ? 127.919 114.637 116.601 1.00 93.23  ? 23  PRO C N   1 
ATOM   1889 C CA  . PRO C 2 24  ? 128.619 114.433 115.335 1.00 93.23  ? 23  PRO C CA  1 
ATOM   1890 C C   . PRO C 2 24  ? 127.701 113.839 114.290 1.00 93.23  ? 23  PRO C C   1 
ATOM   1891 O O   . PRO C 2 24  ? 126.767 113.098 114.597 1.00 93.23  ? 23  PRO C O   1 
ATOM   1892 C CB  . PRO C 2 24  ? 129.736 113.457 115.706 1.00 93.23  ? 23  PRO C CB  1 
ATOM   1893 C CG  . PRO C 2 24  ? 129.212 112.735 116.879 1.00 93.23  ? 23  PRO C CG  1 
ATOM   1894 C CD  . PRO C 2 24  ? 128.406 113.729 117.647 1.00 93.23  ? 23  PRO C CD  1 
ATOM   1895 N N   . ARG C 2 25  ? 127.969 114.182 113.040 1.00 95.53  ? 24  ARG C N   1 
ATOM   1896 C CA  . ARG C 2 25  ? 127.181 113.673 111.931 1.00 95.53  ? 24  ARG C CA  1 
ATOM   1897 C C   . ARG C 2 25  ? 128.130 113.209 110.831 1.00 95.53  ? 24  ARG C C   1 
ATOM   1898 O O   . ARG C 2 25  ? 127.985 113.538 109.654 1.00 95.53  ? 24  ARG C O   1 
ATOM   1899 C CB  . ARG C 2 25  ? 126.187 114.733 111.463 1.00 95.53  ? 24  ARG C CB  1 
ATOM   1900 C CG  . ARG C 2 25  ? 125.028 114.200 110.642 1.00 95.53  ? 24  ARG C CG  1 
ATOM   1901 C CD  . ARG C 2 25  ? 124.052 115.303 110.302 1.00 95.53  ? 24  ARG C CD  1 
ATOM   1902 N NE  . ARG C 2 25  ? 123.422 115.836 111.501 1.00 95.53  ? 24  ARG C NE  1 
ATOM   1903 C CZ  . ARG C 2 25  ? 122.351 115.307 112.079 1.00 95.53  ? 24  ARG C CZ  1 
ATOM   1904 N NH1 . ARG C 2 25  ? 121.780 114.227 111.571 1.00 95.53  ? 24  ARG C NH1 1 
ATOM   1905 N NH2 . ARG C 2 25  ? 121.851 115.862 113.171 1.00 95.53  ? 24  ARG C NH2 1 
ATOM   1906 N N   . GLY C 2 26  ? 129.148 112.457 111.229 1.00 98.23  ? 25  GLY C N   1 
ATOM   1907 C CA  . GLY C 2 26  ? 130.013 111.780 110.284 1.00 98.23  ? 25  GLY C CA  1 
ATOM   1908 C C   . GLY C 2 26  ? 130.961 112.711 109.551 1.00 98.23  ? 25  GLY C C   1 
ATOM   1909 O O   . GLY C 2 26  ? 130.958 113.928 109.712 1.00 98.23  ? 25  GLY C O   1 
ATOM   1910 N N   . VAL C 2 27  ? 131.793 112.097 108.719 1.00 100.07 ? 26  VAL C N   1 
ATOM   1911 C CA  . VAL C 2 27  ? 132.759 112.804 107.894 1.00 100.07 ? 26  VAL C CA  1 
ATOM   1912 C C   . VAL C 2 27  ? 132.401 112.542 106.444 1.00 100.07 ? 26  VAL C C   1 
ATOM   1913 O O   . VAL C 2 27  ? 132.282 111.383 106.032 1.00 100.07 ? 26  VAL C O   1 
ATOM   1914 C CB  . VAL C 2 27  ? 134.195 112.353 108.189 1.00 100.07 ? 26  VAL C CB  1 
ATOM   1915 C CG1 . VAL C 2 27  ? 135.163 113.028 107.244 1.00 100.07 ? 26  VAL C CG1 1 
ATOM   1916 C CG2 . VAL C 2 27  ? 134.552 112.652 109.624 1.00 100.07 ? 26  VAL C CG2 1 
ATOM   1917 N N   . ASN C 2 28  ? 132.211 113.606 105.684 1.00 107.79 ? 27  ASN C N   1 
ATOM   1918 C CA  . ASN C 2 28  ? 131.993 113.493 104.251 1.00 107.79 ? 27  ASN C CA  1 
ATOM   1919 C C   . ASN C 2 28  ? 133.271 112.988 103.595 1.00 107.79 ? 27  ASN C C   1 
ATOM   1920 O O   . ASN C 2 28  ? 134.293 113.681 103.642 1.00 107.79 ? 27  ASN C O   1 
ATOM   1921 C CB  . ASN C 2 28  ? 131.598 114.854 103.687 1.00 107.79 ? 27  ASN C CB  1 
ATOM   1922 C CG  . ASN C 2 28  ? 131.105 114.787 102.256 1.00 107.79 ? 27  ASN C CG  1 
ATOM   1923 O OD1 . ASN C 2 28  ? 131.021 113.720 101.653 1.00 107.79 ? 27  ASN C OD1 1 
ATOM   1924 N ND2 . ASN C 2 28  ? 130.780 115.946 101.700 1.00 107.79 ? 27  ASN C ND2 1 
ATOM   1925 N N   . PRO C 2 29  ? 133.266 111.803 102.978 1.00 113.96 ? 28  PRO C N   1 
ATOM   1926 C CA  . PRO C 2 29  ? 134.510 111.268 102.408 1.00 113.96 ? 28  PRO C CA  1 
ATOM   1927 C C   . PRO C 2 29  ? 134.934 111.937 101.117 1.00 113.96 ? 28  PRO C C   1 
ATOM   1928 O O   . PRO C 2 29  ? 136.074 111.731 100.685 1.00 113.96 ? 28  PRO C O   1 
ATOM   1929 C CB  . PRO C 2 29  ? 134.176 109.794 102.173 1.00 113.96 ? 28  PRO C CB  1 
ATOM   1930 C CG  . PRO C 2 29  ? 132.716 109.794 101.938 1.00 113.96 ? 28  PRO C CG  1 
ATOM   1931 C CD  . PRO C 2 29  ? 132.143 110.867 102.817 1.00 113.96 ? 28  PRO C CD  1 
ATOM   1932 N N   . THR C 2 30  ? 134.063 112.723 100.486 1.00 117.70 ? 29  THR C N   1 
ATOM   1933 C CA  . THR C 2 30  ? 134.421 113.345 99.218  1.00 117.70 ? 29  THR C CA  1 
ATOM   1934 C C   . THR C 2 30  ? 135.388 114.503 99.409  1.00 117.70 ? 29  THR C C   1 
ATOM   1935 O O   . THR C 2 30  ? 136.233 114.751 98.543  1.00 117.70 ? 29  THR C O   1 
ATOM   1936 C CB  . THR C 2 30  ? 133.166 113.831 98.504  1.00 117.70 ? 29  THR C CB  1 
ATOM   1937 O OG1 . THR C 2 30  ? 132.531 114.837 99.300  1.00 117.70 ? 29  THR C OG1 1 
ATOM   1938 C CG2 . THR C 2 30  ? 132.200 112.681 98.299  1.00 117.70 ? 29  THR C CG2 1 
ATOM   1939 N N   . ASN C 2 31  ? 135.282 115.221 100.523 1.00 108.27 ? 30  ASN C N   1 
ATOM   1940 C CA  . ASN C 2 31  ? 136.116 116.391 100.743 1.00 108.27 ? 30  ASN C CA  1 
ATOM   1941 C C   . ASN C 2 31  ? 136.691 116.500 102.147 1.00 108.27 ? 30  ASN C C   1 
ATOM   1942 O O   . ASN C 2 31  ? 137.457 117.432 102.403 1.00 108.27 ? 30  ASN C O   1 
ATOM   1943 C CB  . ASN C 2 31  ? 135.324 117.661 100.409 1.00 108.27 ? 30  ASN C CB  1 
ATOM   1944 C CG  . ASN C 2 31  ? 133.995 117.733 101.139 1.00 108.27 ? 30  ASN C CG  1 
ATOM   1945 O OD1 . ASN C 2 31  ? 133.676 116.888 101.973 1.00 108.27 ? 30  ASN C OD1 1 
ATOM   1946 N ND2 . ASN C 2 31  ? 133.209 118.754 100.822 1.00 108.27 ? 30  ASN C ND2 1 
ATOM   1947 N N   . GLY C 2 32  ? 136.351 115.594 103.056 1.00 102.28 ? 31  GLY C N   1 
ATOM   1948 C CA  . GLY C 2 32  ? 136.910 115.621 104.392 1.00 102.28 ? 31  GLY C CA  1 
ATOM   1949 C C   . GLY C 2 32  ? 136.397 116.762 105.243 1.00 102.28 ? 31  GLY C C   1 
ATOM   1950 O O   . GLY C 2 32  ? 137.185 117.528 105.801 1.00 102.28 ? 31  GLY C O   1 
ATOM   1951 N N   . VAL C 2 33  ? 135.082 116.892 105.348 1.00 95.91  ? 32  VAL C N   1 
ATOM   1952 C CA  . VAL C 2 33  ? 134.455 117.962 106.109 1.00 95.91  ? 32  VAL C CA  1 
ATOM   1953 C C   . VAL C 2 33  ? 133.635 117.319 107.212 1.00 95.91  ? 32  VAL C C   1 
ATOM   1954 O O   . VAL C 2 33  ? 132.614 116.677 106.939 1.00 95.91  ? 32  VAL C O   1 
ATOM   1955 C CB  . VAL C 2 33  ? 133.579 118.855 105.225 1.00 95.91  ? 32  VAL C CB  1 
ATOM   1956 C CG1 . VAL C 2 33  ? 132.877 119.896 106.067 1.00 95.91  ? 32  VAL C CG1 1 
ATOM   1957 C CG2 . VAL C 2 33  ? 134.418 119.512 104.153 1.00 95.91  ? 32  VAL C CG2 1 
ATOM   1958 N N   . ALA C 2 34  ? 134.073 117.482 108.451 1.00 91.90  ? 33  ALA C N   1 
ATOM   1959 C CA  . ALA C 2 34  ? 133.304 116.975 109.573 1.00 91.90  ? 33  ALA C CA  1 
ATOM   1960 C C   . ALA C 2 34  ? 132.161 117.921 109.895 1.00 91.90  ? 33  ALA C C   1 
ATOM   1961 O O   . ALA C 2 34  ? 132.244 119.129 109.659 1.00 91.90  ? 33  ALA C O   1 
ATOM   1962 C CB  . ALA C 2 34  ? 134.188 116.801 110.801 1.00 91.90  ? 33  ALA C CB  1 
ATOM   1963 N N   . SER C 2 35  ? 131.096 117.364 110.459 1.00 91.42  ? 34  SER C N   1 
ATOM   1964 C CA  . SER C 2 35  ? 129.889 118.119 110.740 1.00 91.42  ? 34  SER C CA  1 
ATOM   1965 C C   . SER C 2 35  ? 129.427 117.870 112.165 1.00 91.42  ? 34  SER C C   1 
ATOM   1966 O O   . SER C 2 35  ? 129.704 116.826 112.757 1.00 91.42  ? 34  SER C O   1 
ATOM   1967 C CB  . SER C 2 35  ? 128.774 117.753 109.770 1.00 91.42  ? 34  SER C CB  1 
ATOM   1968 O OG  . SER C 2 35  ? 129.136 118.092 108.446 1.00 91.42  ? 34  SER C OG  1 
ATOM   1969 N N   . LEU C 2 36  ? 128.720 118.852 112.707 1.00 93.49  ? 35  LEU C N   1 
ATOM   1970 C CA  . LEU C 2 36  ? 128.136 118.800 114.033 1.00 93.49  ? 35  LEU C CA  1 
ATOM   1971 C C   . LEU C 2 36  ? 126.780 119.473 113.948 1.00 93.49  ? 35  LEU C C   1 
ATOM   1972 O O   . LEU C 2 36  ? 126.616 120.444 113.204 1.00 93.49  ? 35  LEU C O   1 
ATOM   1973 C CB  . LEU C 2 36  ? 129.001 119.526 115.063 1.00 93.49  ? 35  LEU C CB  1 
ATOM   1974 C CG  . LEU C 2 36  ? 130.408 119.010 115.335 1.00 93.49  ? 35  LEU C CG  1 
ATOM   1975 C CD1 . LEU C 2 36  ? 131.142 119.958 116.250 1.00 93.49  ? 35  LEU C CD1 1 
ATOM   1976 C CD2 . LEU C 2 36  ? 130.346 117.647 115.950 1.00 93.49  ? 35  LEU C CD2 1 
ATOM   1977 N N   . SER C 2 37  ? 125.815 118.975 114.711 1.00 97.29  ? 36  SER C N   1 
ATOM   1978 C CA  . SER C 2 37  ? 124.479 119.539 114.608 1.00 97.29  ? 36  SER C CA  1 
ATOM   1979 C C   . SER C 2 37  ? 123.772 119.458 115.947 1.00 97.29  ? 36  SER C C   1 
ATOM   1980 O O   . SER C 2 37  ? 124.062 118.586 116.765 1.00 97.29  ? 36  SER C O   1 
ATOM   1981 C CB  . SER C 2 37  ? 123.658 118.816 113.547 1.00 97.29  ? 36  SER C CB  1 
ATOM   1982 O OG  . SER C 2 37  ? 123.419 117.487 113.955 1.00 97.29  ? 36  SER C OG  1 
ATOM   1983 N N   . GLN C 2 38  ? 122.843 120.381 116.162 1.00 98.42  ? 37  GLN C N   1 
ATOM   1984 C CA  . GLN C 2 38  ? 121.994 120.333 117.339 1.00 98.42  ? 37  GLN C CA  1 
ATOM   1985 C C   . GLN C 2 38  ? 120.867 119.339 117.109 1.00 98.42  ? 37  GLN C C   1 
ATOM   1986 O O   . GLN C 2 38  ? 120.291 119.278 116.021 1.00 98.42  ? 37  GLN C O   1 
ATOM   1987 C CB  . GLN C 2 38  ? 121.417 121.712 117.643 1.00 98.42  ? 37  GLN C CB  1 
ATOM   1988 C CG  . GLN C 2 38  ? 120.630 121.783 118.935 1.00 98.42  ? 37  GLN C CG  1 
ATOM   1989 C CD  . GLN C 2 38  ? 120.049 123.152 119.188 1.00 98.42  ? 37  GLN C CD  1 
ATOM   1990 O OE1 . GLN C 2 38  ? 120.169 124.051 118.360 1.00 98.42  ? 37  GLN C OE1 1 
ATOM   1991 N NE2 . GLN C 2 38  ? 119.417 123.323 120.341 1.00 98.42  ? 37  GLN C NE2 1 
ATOM   1992 N N   . ALA C 2 39  ? 120.552 118.557 118.139 1.00 108.40 ? 38  ALA C N   1 
ATOM   1993 C CA  . ALA C 2 39  ? 119.520 117.525 118.043 1.00 108.40 ? 38  ALA C CA  1 
ATOM   1994 C C   . ALA C 2 39  ? 118.148 118.191 118.058 1.00 108.40 ? 38  ALA C C   1 
ATOM   1995 O O   . ALA C 2 39  ? 117.450 118.240 119.072 1.00 108.40 ? 38  ALA C O   1 
ATOM   1996 C CB  . ALA C 2 39  ? 119.665 116.517 119.173 1.00 108.40 ? 38  ALA C CB  1 
ATOM   1997 N N   . GLY C 2 40  ? 117.753 118.707 116.895 1.00 106.86 ? 39  GLY C N   1 
ATOM   1998 C CA  . GLY C 2 40  ? 116.480 119.378 116.755 1.00 106.86 ? 39  GLY C CA  1 
ATOM   1999 C C   . GLY C 2 40  ? 115.354 118.414 116.436 1.00 106.86 ? 39  GLY C C   1 
ATOM   2000 O O   . GLY C 2 40  ? 115.532 117.201 116.343 1.00 106.86 ? 39  GLY C O   1 
ATOM   2001 N N   . ALA C 2 41  ? 114.161 118.983 116.270 1.00 106.35 ? 40  ALA C N   1 
ATOM   2002 C CA  . ALA C 2 41  ? 113.000 118.175 115.918 1.00 106.35 ? 40  ALA C CA  1 
ATOM   2003 C C   . ALA C 2 41  ? 112.995 117.848 114.432 1.00 106.35 ? 40  ALA C C   1 
ATOM   2004 O O   . ALA C 2 41  ? 113.070 116.681 114.039 1.00 106.35 ? 40  ALA C O   1 
ATOM   2005 C CB  . ALA C 2 41  ? 111.714 118.904 116.310 1.00 106.35 ? 40  ALA C CB  1 
ATOM   2006 N N   . VAL C 2 42  ? 112.918 118.872 113.593 1.00 101.44 ? 41  VAL C N   1 
ATOM   2007 C CA  . VAL C 2 42  ? 112.918 118.679 112.150 1.00 101.44 ? 41  VAL C CA  1 
ATOM   2008 C C   . VAL C 2 42  ? 114.346 118.875 111.661 1.00 101.44 ? 41  VAL C C   1 
ATOM   2009 O O   . VAL C 2 42  ? 114.982 119.870 112.028 1.00 101.44 ? 41  VAL C O   1 
ATOM   2010 C CB  . VAL C 2 42  ? 111.947 119.650 111.468 1.00 101.44 ? 41  VAL C CB  1 
ATOM   2011 C CG1 . VAL C 2 42  ? 111.941 119.432 109.971 1.00 101.44 ? 41  VAL C CG1 1 
ATOM   2012 C CG2 . VAL C 2 42  ? 110.563 119.486 112.047 1.00 101.44 ? 41  VAL C CG2 1 
ATOM   2013 N N   . PRO C 2 43  ? 114.891 117.963 110.850 1.00 98.50  ? 42  PRO C N   1 
ATOM   2014 C CA  . PRO C 2 43  ? 116.292 118.091 110.419 1.00 98.50  ? 42  PRO C CA  1 
ATOM   2015 C C   . PRO C 2 43  ? 116.567 119.264 109.500 1.00 98.50  ? 42  PRO C C   1 
ATOM   2016 O O   . PRO C 2 43  ? 117.741 119.588 109.290 1.00 98.50  ? 42  PRO C O   1 
ATOM   2017 C CB  . PRO C 2 43  ? 116.555 116.767 109.698 1.00 98.50  ? 42  PRO C CB  1 
ATOM   2018 C CG  . PRO C 2 43  ? 115.572 115.835 110.267 1.00 98.50  ? 42  PRO C CG  1 
ATOM   2019 C CD  . PRO C 2 43  ? 114.343 116.644 110.515 1.00 98.50  ? 42  PRO C CD  1 
ATOM   2020 N N   . ALA C 2 44  ? 115.544 119.905 108.941 1.00 97.88  ? 43  ALA C N   1 
ATOM   2021 C CA  . ALA C 2 44  ? 115.787 121.137 108.205 1.00 97.88  ? 43  ALA C CA  1 
ATOM   2022 C C   . ALA C 2 44  ? 116.147 122.278 109.141 1.00 97.88  ? 43  ALA C C   1 
ATOM   2023 O O   . ALA C 2 44  ? 116.842 123.212 108.736 1.00 97.88  ? 43  ALA C O   1 
ATOM   2024 C CB  . ALA C 2 44  ? 114.564 121.506 107.373 1.00 97.88  ? 43  ALA C CB  1 
ATOM   2025 N N   . LEU C 2 45  ? 115.680 122.226 110.384 1.00 100.89 ? 44  LEU C N   1 
ATOM   2026 C CA  . LEU C 2 45  ? 115.952 123.261 111.374 1.00 100.89 ? 44  LEU C CA  1 
ATOM   2027 C C   . LEU C 2 45  ? 116.994 122.738 112.356 1.00 100.89 ? 44  LEU C C   1 
ATOM   2028 O O   . LEU C 2 45  ? 116.677 122.313 113.465 1.00 100.89 ? 44  LEU C O   1 
ATOM   2029 C CB  . LEU C 2 45  ? 114.684 123.644 112.074 1.00 100.89 ? 44  LEU C CB  1 
ATOM   2030 C CG  . LEU C 2 45  ? 113.631 124.181 111.119 1.00 100.89 ? 44  LEU C CG  1 
ATOM   2031 C CD1 . LEU C 2 45  ? 112.357 124.526 111.862 1.00 100.89 ? 44  LEU C CD1 1 
ATOM   2032 C CD2 . LEU C 2 45  ? 114.189 125.373 110.400 1.00 100.89 ? 44  LEU C CD2 1 
ATOM   2033 N N   . GLU C 2 46  ? 118.256 122.793 111.949 1.00 100.87 ? 45  GLU C N   1 
ATOM   2034 C CA  . GLU C 2 46  ? 119.348 122.326 112.789 1.00 100.87 ? 45  GLU C CA  1 
ATOM   2035 C C   . GLU C 2 46  ? 120.508 123.292 112.654 1.00 100.87 ? 45  GLU C C   1 
ATOM   2036 O O   . GLU C 2 46  ? 120.974 123.552 111.541 1.00 100.87 ? 45  GLU C O   1 
ATOM   2037 C CB  . GLU C 2 46  ? 119.784 120.906 112.412 1.00 100.87 ? 45  GLU C CB  1 
ATOM   2038 C CG  . GLU C 2 46  ? 118.808 119.807 112.807 1.00 100.87 ? 45  GLU C CG  1 
ATOM   2039 C CD  . GLU C 2 46  ? 119.284 118.418 112.413 1.00 100.87 ? 45  GLU C CD  1 
ATOM   2040 O OE1 . GLU C 2 46  ? 120.298 118.307 111.693 1.00 100.87 ? 45  GLU C OE1 1 
ATOM   2041 O OE2 . GLU C 2 46  ? 118.643 117.434 112.835 1.00 100.87 ? 45  GLU C OE2 1 
ATOM   2042 N N   . LYS C 2 47  ? 120.966 123.819 113.782 1.00 97.49  ? 46  LYS C N   1 
ATOM   2043 C CA  . LYS C 2 47  ? 122.126 124.698 113.813 1.00 97.49  ? 46  LYS C CA  1 
ATOM   2044 C C   . LYS C 2 47  ? 123.368 123.887 113.483 1.00 97.49  ? 46  LYS C C   1 
ATOM   2045 O O   . LYS C 2 47  ? 123.800 123.058 114.286 1.00 97.49  ? 46  LYS C O   1 
ATOM   2046 C CB  . LYS C 2 47  ? 122.233 125.333 115.191 1.00 97.49  ? 46  LYS C CB  1 
ATOM   2047 C CG  . LYS C 2 47  ? 121.053 126.213 115.520 1.00 97.49  ? 46  LYS C CG  1 
ATOM   2048 C CD  . LYS C 2 47  ? 121.192 126.860 116.874 1.00 97.49  ? 46  LYS C CD  1 
ATOM   2049 C CE  . LYS C 2 47  ? 120.019 127.774 117.147 1.00 97.49  ? 46  LYS C CE  1 
ATOM   2050 N NZ  . LYS C 2 47  ? 118.759 126.997 117.284 1.00 97.49  ? 46  LYS C NZ  1 
ATOM   2051 N N   . ARG C 2 48  ? 123.944 124.101 112.306 1.00 91.87  ? 47  ARG C N   1 
ATOM   2052 C CA  . ARG C 2 48  ? 124.992 123.217 111.820 1.00 91.87  ? 47  ARG C CA  1 
ATOM   2053 C C   . ARG C 2 48  ? 126.354 123.889 111.877 1.00 91.87  ? 47  ARG C C   1 
ATOM   2054 O O   . ARG C 2 48  ? 126.479 125.094 111.636 1.00 91.87  ? 47  ARG C O   1 
ATOM   2055 C CB  . ARG C 2 48  ? 124.699 122.737 110.401 1.00 91.87  ? 47  ARG C CB  1 
ATOM   2056 C CG  . ARG C 2 48  ? 123.590 121.706 110.353 1.00 91.87  ? 47  ARG C CG  1 
ATOM   2057 C CD  . ARG C 2 48  ? 123.518 121.022 109.005 1.00 91.87  ? 47  ARG C CD  1 
ATOM   2058 N NE  . ARG C 2 48  ? 123.132 121.945 107.947 1.00 91.87  ? 47  ARG C NE  1 
ATOM   2059 C CZ  . ARG C 2 48  ? 121.874 122.203 107.614 1.00 91.87  ? 47  ARG C CZ  1 
ATOM   2060 N NH1 . ARG C 2 48  ? 120.884 121.607 108.260 1.00 91.87  ? 47  ARG C NH1 1 
ATOM   2061 N NH2 . ARG C 2 48  ? 121.605 123.058 106.638 1.00 91.87  ? 47  ARG C NH2 1 
ATOM   2062 N N   . VAL C 2 49  ? 127.367 123.100 112.224 1.00 88.07  ? 48  VAL C N   1 
ATOM   2063 C CA  . VAL C 2 49  ? 128.742 123.560 112.360 1.00 88.07  ? 48  VAL C CA  1 
ATOM   2064 C C   . VAL C 2 49  ? 129.630 122.572 111.628 1.00 88.07  ? 48  VAL C C   1 
ATOM   2065 O O   . VAL C 2 49  ? 129.697 121.403 112.010 1.00 88.07  ? 48  VAL C O   1 
ATOM   2066 C CB  . VAL C 2 49  ? 129.179 123.658 113.829 1.00 88.07  ? 48  VAL C CB  1 
ATOM   2067 C CG1 . VAL C 2 49  ? 130.653 123.960 113.908 1.00 88.07  ? 48  VAL C CG1 1 
ATOM   2068 C CG2 . VAL C 2 49  ? 128.390 124.709 114.566 1.00 88.07  ? 48  VAL C CG2 1 
ATOM   2069 N N   . THR C 2 50  ? 130.316 123.027 110.592 1.00 88.27  ? 49  THR C N   1 
ATOM   2070 C CA  . THR C 2 50  ? 131.222 122.175 109.844 1.00 88.27  ? 49  THR C CA  1 
ATOM   2071 C C   . THR C 2 50  ? 132.652 122.652 110.039 1.00 88.27  ? 49  THR C C   1 
ATOM   2072 O O   . THR C 2 50  ? 132.908 123.848 110.178 1.00 88.27  ? 49  THR C O   1 
ATOM   2073 C CB  . THR C 2 50  ? 130.878 122.181 108.359 1.00 88.27  ? 49  THR C CB  1 
ATOM   2074 O OG1 . THR C 2 50  ? 131.095 123.492 107.833 1.00 88.27  ? 49  THR C OG1 1 
ATOM   2075 C CG2 . THR C 2 50  ? 129.423 121.817 108.159 1.00 88.27  ? 49  THR C CG2 1 
ATOM   2076 N N   . VAL C 2 51  ? 133.582 121.708 110.040 1.00 86.98  ? 50  VAL C N   1 
ATOM   2077 C CA  . VAL C 2 51  ? 134.993 122.010 110.237 1.00 86.98  ? 50  VAL C CA  1 
ATOM   2078 C C   . VAL C 2 51  ? 135.811 121.116 109.314 1.00 86.98  ? 50  VAL C C   1 
ATOM   2079 O O   . VAL C 2 51  ? 135.487 119.939 109.124 1.00 86.98  ? 50  VAL C O   1 
ATOM   2080 C CB  . VAL C 2 51  ? 135.386 121.865 111.727 1.00 86.98  ? 50  VAL C CB  1 
ATOM   2081 C CG1 . VAL C 2 51  ? 135.057 120.492 112.260 1.00 86.98  ? 50  VAL C CG1 1 
ATOM   2082 C CG2 . VAL C 2 51  ? 136.850 122.167 111.947 1.00 86.98  ? 50  VAL C CG2 1 
ATOM   2083 N N   . SER C 2 52  ? 136.831 121.692 108.680 1.00 87.82  ? 51  SER C N   1 
ATOM   2084 C CA  . SER C 2 52  ? 137.675 120.915 107.781 1.00 87.82  ? 51  SER C CA  1 
ATOM   2085 C C   . SER C 2 52  ? 139.079 121.487 107.786 1.00 87.82  ? 51  SER C C   1 
ATOM   2086 O O   . SER C 2 52  ? 139.274 122.665 107.471 1.00 87.82  ? 51  SER C O   1 
ATOM   2087 C CB  . SER C 2 52  ? 137.115 120.915 106.365 1.00 87.82  ? 51  SER C CB  1 
ATOM   2088 O OG  . SER C 2 52  ? 137.212 122.203 105.795 1.00 87.82  ? 51  SER C OG  1 
ATOM   2089 N N   . VAL C 2 53  ? 140.044 120.652 108.150 1.00 92.78  ? 52  VAL C N   1 
ATOM   2090 C CA  . VAL C 2 53  ? 141.455 120.967 107.993 1.00 92.78  ? 52  VAL C CA  1 
ATOM   2091 C C   . VAL C 2 53  ? 141.830 120.460 106.606 1.00 92.78  ? 52  VAL C C   1 
ATOM   2092 O O   . VAL C 2 53  ? 141.068 119.704 105.996 1.00 92.78  ? 52  VAL C O   1 
ATOM   2093 C CB  . VAL C 2 53  ? 142.288 120.312 109.109 1.00 92.78  ? 52  VAL C CB  1 
ATOM   2094 C CG1 . VAL C 2 53  ? 142.409 118.843 108.869 1.00 92.78  ? 52  VAL C CG1 1 
ATOM   2095 C CG2 . VAL C 2 53  ? 143.651 120.960 109.277 1.00 92.78  ? 52  VAL C CG2 1 
ATOM   2096 N N   . SER C 2 54  ? 142.971 120.889 106.075 1.00 97.36  ? 53  SER C N   1 
ATOM   2097 C CA  . SER C 2 54  ? 143.369 120.448 104.747 1.00 97.36  ? 53  SER C CA  1 
ATOM   2098 C C   . SER C 2 54  ? 144.761 119.838 104.742 1.00 97.36  ? 53  SER C C   1 
ATOM   2099 O O   . SER C 2 54  ? 145.347 119.590 105.799 1.00 97.36  ? 53  SER C O   1 
ATOM   2100 C CB  . SER C 2 54  ? 143.311 121.611 103.760 1.00 97.36  ? 53  SER C CB  1 
ATOM   2101 O OG  . SER C 2 54  ? 143.756 121.203 102.479 1.00 97.36  ? 53  SER C OG  1 
ATOM   2102 N N   . GLN C 2 55  ? 145.277 119.583 103.548 1.00 111.72 ? 54  GLN C N   1 
ATOM   2103 C CA  . GLN C 2 55  ? 146.595 119.026 103.296 1.00 111.72 ? 54  GLN C CA  1 
ATOM   2104 C C   . GLN C 2 55  ? 147.205 119.813 102.144 1.00 111.72 ? 54  GLN C C   1 
ATOM   2105 O O   . GLN C 2 55  ? 146.483 120.495 101.411 1.00 111.72 ? 54  GLN C O   1 
ATOM   2106 C CB  . GLN C 2 55  ? 146.508 117.532 102.945 1.00 111.72 ? 54  GLN C CB  1 
ATOM   2107 C CG  . GLN C 2 55  ? 146.016 116.619 104.064 1.00 111.72 ? 54  GLN C CG  1 
ATOM   2108 C CD  . GLN C 2 55  ? 146.965 116.556 105.243 1.00 111.72 ? 54  GLN C CD  1 
ATOM   2109 O OE1 . GLN C 2 55  ? 146.659 117.043 106.328 1.00 111.72 ? 54  GLN C OE1 1 
ATOM   2110 N NE2 . GLN C 2 55  ? 148.126 115.951 105.035 1.00 111.72 ? 54  GLN C NE2 1 
ATOM   2111 N N   . PRO C 2 56  ? 148.540 119.766 101.976 1.00 116.59 ? 55  PRO C N   1 
ATOM   2112 C CA  . PRO C 2 56  ? 149.087 120.484 100.820 1.00 116.59 ? 55  PRO C CA  1 
ATOM   2113 C C   . PRO C 2 56  ? 148.826 119.761 99.504  1.00 116.59 ? 55  PRO C C   1 
ATOM   2114 O O   . PRO C 2 56  ? 148.851 120.400 98.452  1.00 116.59 ? 55  PRO C O   1 
ATOM   2115 C CB  . PRO C 2 56  ? 150.590 120.534 101.113 1.00 116.59 ? 55  PRO C CB  1 
ATOM   2116 C CG  . PRO C 2 56  ? 150.704 120.322 102.569 1.00 116.59 ? 55  PRO C CG  1 
ATOM   2117 C CD  . PRO C 2 56  ? 149.608 119.364 102.902 1.00 116.59 ? 55  PRO C CD  1 
ATOM   2118 N N   . LYS C 2 61  ? 152.251 123.238 99.063  1.00 115.95 ? 60  LYS C N   1 
ATOM   2119 C CA  . LYS C 2 61  ? 151.636 124.558 99.118  1.00 115.95 ? 60  LYS C CA  1 
ATOM   2120 C C   . LYS C 2 61  ? 151.675 125.117 100.533 1.00 115.95 ? 60  LYS C C   1 
ATOM   2121 O O   . LYS C 2 61  ? 152.718 125.555 101.012 1.00 115.95 ? 60  LYS C O   1 
ATOM   2122 C CB  . LYS C 2 61  ? 150.188 124.502 98.623  1.00 115.95 ? 60  LYS C CB  1 
ATOM   2123 C CG  . LYS C 2 61  ? 150.026 124.130 97.165  1.00 115.95 ? 60  LYS C CG  1 
ATOM   2124 C CD  . LYS C 2 61  ? 148.563 124.112 96.771  1.00 115.95 ? 60  LYS C CD  1 
ATOM   2125 C CE  . LYS C 2 61  ? 148.404 123.798 95.298  1.00 115.95 ? 60  LYS C CE  1 
ATOM   2126 N NZ  . LYS C 2 61  ? 148.824 122.403 94.989  1.00 115.95 ? 60  LYS C NZ  1 
ATOM   2127 N N   . ASN C 2 62  ? 150.521 125.083 101.194 1.00 109.85 ? 61  ASN C N   1 
ATOM   2128 C CA  . ASN C 2 62  ? 150.357 125.631 102.530 1.00 109.85 ? 61  ASN C CA  1 
ATOM   2129 C C   . ASN C 2 62  ? 149.111 125.036 103.167 1.00 109.85 ? 61  ASN C C   1 
ATOM   2130 O O   . ASN C 2 62  ? 148.193 124.598 102.472 1.00 109.85 ? 61  ASN C O   1 
ATOM   2131 C CB  . ASN C 2 62  ? 150.287 127.159 102.493 1.00 109.85 ? 61  ASN C CB  1 
ATOM   2132 C CG  . ASN C 2 62  ? 149.289 127.679 101.477 1.00 109.85 ? 61  ASN C CG  1 
ATOM   2133 O OD1 . ASN C 2 62  ? 148.610 126.912 100.796 1.00 109.85 ? 61  ASN C OD1 1 
ATOM   2134 N ND2 . ASN C 2 62  ? 149.196 128.997 101.371 1.00 109.85 ? 61  ASN C ND2 1 
ATOM   2135 N N   . TYR C 2 63  ? 149.099 125.018 104.494 1.00 99.75  ? 62  TYR C N   1 
ATOM   2136 C CA  . TYR C 2 63  ? 147.993 124.444 105.240 1.00 99.75  ? 62  TYR C CA  1 
ATOM   2137 C C   . TYR C 2 63  ? 146.781 125.366 105.206 1.00 99.75  ? 62  TYR C C   1 
ATOM   2138 O O   . TYR C 2 63  ? 146.881 126.554 104.897 1.00 99.75  ? 62  TYR C O   1 
ATOM   2139 C CB  . TYR C 2 63  ? 148.425 124.184 106.677 1.00 99.75  ? 62  TYR C CB  1 
ATOM   2140 C CG  . TYR C 2 63  ? 149.319 122.985 106.821 1.00 99.75  ? 62  TYR C CG  1 
ATOM   2141 C CD1 . TYR C 2 63  ? 149.197 121.906 105.970 1.00 99.75  ? 62  TYR C CD1 1 
ATOM   2142 C CD2 . TYR C 2 63  ? 150.344 122.968 107.754 1.00 99.75  ? 62  TYR C CD2 1 
ATOM   2143 C CE1 . TYR C 2 63  ? 150.018 120.811 106.096 1.00 99.75  ? 62  TYR C CE1 1 
ATOM   2144 C CE2 . TYR C 2 63  ? 151.178 121.878 107.877 1.00 99.75  ? 62  TYR C CE2 1 
ATOM   2145 C CZ  . TYR C 2 63  ? 151.010 120.803 107.041 1.00 99.75  ? 62  TYR C CZ  1 
ATOM   2146 O OH  . TYR C 2 63  ? 151.838 119.711 107.153 1.00 99.75  ? 62  TYR C OH  1 
ATOM   2147 N N   . LYS C 2 64  ? 145.624 124.801 105.540 1.00 90.56  ? 63  LYS C N   1 
ATOM   2148 C CA  . LYS C 2 64  ? 144.373 125.545 105.477 1.00 90.56  ? 63  LYS C CA  1 
ATOM   2149 C C   . LYS C 2 64  ? 143.357 124.898 106.400 1.00 90.56  ? 63  LYS C C   1 
ATOM   2150 O O   . LYS C 2 64  ? 143.110 123.695 106.302 1.00 90.56  ? 63  LYS C O   1 
ATOM   2151 C CB  . LYS C 2 64  ? 143.830 125.582 104.054 1.00 90.56  ? 63  LYS C CB  1 
ATOM   2152 C CG  . LYS C 2 64  ? 142.588 126.423 103.909 1.00 90.56  ? 63  LYS C CG  1 
ATOM   2153 C CD  . LYS C 2 64  ? 142.107 126.432 102.479 1.00 90.56  ? 63  LYS C CD  1 
ATOM   2154 C CE  . LYS C 2 64  ? 143.060 127.214 101.603 1.00 90.56  ? 63  LYS C CE  1 
ATOM   2155 N NZ  . LYS C 2 64  ? 143.070 128.653 101.966 1.00 90.56  ? 63  LYS C NZ  1 
ATOM   2156 N N   . VAL C 2 65  ? 142.775 125.694 107.289 1.00 85.25  ? 64  VAL C N   1 
ATOM   2157 C CA  . VAL C 2 65  ? 141.732 125.248 108.201 1.00 85.25  ? 64  VAL C CA  1 
ATOM   2158 C C   . VAL C 2 65  ? 140.526 126.138 107.967 1.00 85.25  ? 64  VAL C C   1 
ATOM   2159 O O   . VAL C 2 65  ? 140.679 127.353 107.834 1.00 85.25  ? 64  VAL C O   1 
ATOM   2160 C CB  . VAL C 2 65  ? 142.191 125.348 109.669 1.00 85.25  ? 64  VAL C CB  1 
ATOM   2161 C CG1 . VAL C 2 65  ? 141.119 124.849 110.612 1.00 85.25  ? 64  VAL C CG1 1 
ATOM   2162 C CG2 . VAL C 2 65  ? 143.487 124.610 109.885 1.00 85.25  ? 64  VAL C CG2 1 
ATOM   2163 N N   . GLN C 2 66  ? 139.333 125.560 107.902 1.00 88.21  ? 65  GLN C N   1 
ATOM   2164 C CA  . GLN C 2 66  ? 138.163 126.419 107.846 1.00 88.21  ? 65  GLN C CA  1 
ATOM   2165 C C   . GLN C 2 66  ? 137.027 125.836 108.666 1.00 88.21  ? 65  GLN C C   1 
ATOM   2166 O O   . GLN C 2 66  ? 136.895 124.618 108.819 1.00 88.21  ? 65  GLN C O   1 
ATOM   2167 C CB  . GLN C 2 66  ? 137.700 126.681 106.415 1.00 88.21  ? 65  GLN C CB  1 
ATOM   2168 C CG  . GLN C 2 66  ? 137.168 125.495 105.684 1.00 88.21  ? 65  GLN C CG  1 
ATOM   2169 C CD  . GLN C 2 66  ? 136.749 125.858 104.284 1.00 88.21  ? 65  GLN C CD  1 
ATOM   2170 O OE1 . GLN C 2 66  ? 136.809 127.022 103.893 1.00 88.21  ? 65  GLN C OE1 1 
ATOM   2171 N NE2 . GLN C 2 66  ? 136.321 124.865 103.515 1.00 88.21  ? 65  GLN C NE2 1 
ATOM   2172 N N   . VAL C 2 67  ? 136.228 126.742 109.223 1.00 85.07  ? 66  VAL C N   1 
ATOM   2173 C CA  . VAL C 2 67  ? 135.066 126.409 110.039 1.00 85.07  ? 66  VAL C CA  1 
ATOM   2174 C C   . VAL C 2 67  ? 133.889 127.194 109.496 1.00 85.07  ? 66  VAL C C   1 
ATOM   2175 O O   . VAL C 2 67  ? 133.926 128.426 109.474 1.00 85.07  ? 66  VAL C O   1 
ATOM   2176 C CB  . VAL C 2 67  ? 135.274 126.741 111.524 1.00 85.07  ? 66  VAL C CB  1 
ATOM   2177 C CG1 . VAL C 2 67  ? 133.987 126.531 112.286 1.00 85.07  ? 66  VAL C CG1 1 
ATOM   2178 C CG2 . VAL C 2 67  ? 136.383 125.907 112.115 1.00 85.07  ? 66  VAL C CG2 1 
ATOM   2179 N N   . LYS C 2 68  ? 132.848 126.495 109.069 1.00 86.92  ? 67  LYS C N   1 
ATOM   2180 C CA  . LYS C 2 68  ? 131.667 127.131 108.503 1.00 86.92  ? 67  LYS C CA  1 
ATOM   2181 C C   . LYS C 2 68  ? 130.470 126.816 109.385 1.00 86.92  ? 67  LYS C C   1 
ATOM   2182 O O   . LYS C 2 68  ? 130.067 125.657 109.497 1.00 86.92  ? 67  LYS C O   1 
ATOM   2183 C CB  . LYS C 2 68  ? 131.429 126.651 107.075 1.00 86.92  ? 67  LYS C CB  1 
ATOM   2184 C CG  . LYS C 2 68  ? 130.313 127.363 106.360 1.00 86.92  ? 67  LYS C CG  1 
ATOM   2185 C CD  . LYS C 2 68  ? 130.131 126.801 104.964 1.00 86.92  ? 67  LYS C CD  1 
ATOM   2186 C CE  . LYS C 2 68  ? 130.882 127.620 103.932 1.00 86.92  ? 67  LYS C CE  1 
ATOM   2187 N NZ  . LYS C 2 68  ? 132.337 127.321 103.918 1.00 86.92  ? 67  LYS C NZ  1 
ATOM   2188 N N   . ILE C 2 69  ? 129.901 127.842 110.002 1.00 83.23  ? 68  ILE C N   1 
ATOM   2189 C CA  . ILE C 2 69  ? 128.836 127.700 110.983 1.00 83.23  ? 68  ILE C CA  1 
ATOM   2190 C C   . ILE C 2 69  ? 127.613 128.462 110.499 1.00 83.23  ? 68  ILE C C   1 
ATOM   2191 O O   . ILE C 2 69  ? 127.713 129.633 110.119 1.00 83.23  ? 68  ILE C O   1 
ATOM   2192 C CB  . ILE C 2 69  ? 129.299 128.190 112.367 1.00 83.23  ? 68  ILE C CB  1 
ATOM   2193 C CG1 . ILE C 2 69  ? 128.148 128.243 113.355 1.00 83.23  ? 68  ILE C CG1 1 
ATOM   2194 C CG2 . ILE C 2 69  ? 130.066 129.495 112.291 1.00 83.23  ? 68  ILE C CG2 1 
ATOM   2195 C CD1 . ILE C 2 69  ? 128.630 128.488 114.727 1.00 83.23  ? 68  ILE C CD1 1 
ATOM   2196 N N   . GLN C 2 70  ? 126.458 127.801 110.494 1.00 92.26  ? 69  GLN C N   1 
ATOM   2197 C CA  . GLN C 2 70  ? 125.258 128.471 110.027 1.00 92.26  ? 69  GLN C CA  1 
ATOM   2198 C C   . GLN C 2 70  ? 124.050 128.048 110.849 1.00 92.26  ? 69  GLN C C   1 
ATOM   2199 O O   . GLN C 2 70  ? 123.900 126.876 111.215 1.00 92.26  ? 69  GLN C O   1 
ATOM   2200 C CB  . GLN C 2 70  ? 125.056 128.230 108.524 1.00 92.26  ? 69  GLN C CB  1 
ATOM   2201 C CG  . GLN C 2 70  ? 124.934 126.795 108.084 1.00 92.26  ? 69  GLN C CG  1 
ATOM   2202 C CD  . GLN C 2 70  ? 123.504 126.327 108.061 1.00 92.26  ? 69  GLN C CD  1 
ATOM   2203 O OE1 . GLN C 2 70  ? 122.585 127.120 107.867 1.00 92.26  ? 69  GLN C OE1 1 
ATOM   2204 N NE2 . GLN C 2 70  ? 123.303 125.032 108.248 1.00 92.26  ? 69  GLN C NE2 1 
ATOM   2205 N N   . ASN C 2 71  ? 123.210 129.036 111.152 1.00 96.08  ? 70  ASN C N   1 
ATOM   2206 C CA  . ASN C 2 71  ? 122.019 128.889 111.972 1.00 96.08  ? 70  ASN C CA  1 
ATOM   2207 C C   . ASN C 2 71  ? 120.825 129.351 111.156 1.00 96.08  ? 70  ASN C C   1 
ATOM   2208 O O   . ASN C 2 71  ? 120.809 130.510 110.709 1.00 96.08  ? 70  ASN C O   1 
ATOM   2209 C CB  . ASN C 2 71  ? 122.119 129.731 113.237 1.00 96.08  ? 70  ASN C CB  1 
ATOM   2210 C CG  . ASN C 2 71  ? 123.385 129.479 114.001 1.00 96.08  ? 70  ASN C CG  1 
ATOM   2211 O OD1 . ASN C 2 71  ? 124.184 130.384 114.190 1.00 96.08  ? 70  ASN C OD1 1 
ATOM   2212 N ND2 . ASN C 2 71  ? 123.592 128.249 114.425 1.00 96.08  ? 70  ASN C ND2 1 
ATOM   2213 N N   . PRO C 2 72  ? 119.829 128.512 110.910 1.00 96.64  ? 71  PRO C N   1 
ATOM   2214 C CA  . PRO C 2 72  ? 118.597 128.985 110.282 1.00 96.64  ? 71  PRO C CA  1 
ATOM   2215 C C   . PRO C 2 72  ? 117.538 129.346 111.309 1.00 96.64  ? 71  PRO C C   1 
ATOM   2216 O O   . PRO C 2 72  ? 117.504 128.819 112.420 1.00 96.64  ? 71  PRO C O   1 
ATOM   2217 C CB  . PRO C 2 72  ? 118.153 127.772 109.457 1.00 96.64  ? 71  PRO C CB  1 
ATOM   2218 C CG  . PRO C 2 72  ? 118.642 126.622 110.245 1.00 96.64  ? 71  PRO C CG  1 
ATOM   2219 C CD  . PRO C 2 72  ? 119.937 127.047 110.869 1.00 96.64  ? 71  PRO C CD  1 
ATOM   2220 N N   . THR C 2 73  ? 116.661 130.268 110.917 1.00 105.58 ? 72  THR C N   1 
ATOM   2221 C CA  . THR C 2 73  ? 115.465 130.576 111.688 1.00 105.58 ? 72  THR C CA  1 
ATOM   2222 C C   . THR C 2 73  ? 114.250 130.425 110.791 1.00 105.58 ? 72  THR C C   1 
ATOM   2223 O O   . THR C 2 73  ? 114.311 130.695 109.589 1.00 105.58 ? 72  THR C O   1 
ATOM   2224 C CB  . THR C 2 73  ? 115.484 131.990 112.271 1.00 105.58 ? 72  THR C CB  1 
ATOM   2225 O OG1 . THR C 2 73  ? 115.592 132.943 111.209 1.00 105.58 ? 72  THR C OG1 1 
ATOM   2226 C CG2 . THR C 2 73  ? 116.642 132.164 113.229 1.00 105.58 ? 72  THR C CG2 1 
ATOM   2227 N N   . ALA C 2 74  ? 113.140 129.994 111.382 1.00 111.78 ? 73  ALA C N   1 
ATOM   2228 C CA  . ALA C 2 74  ? 111.954 129.684 110.605 1.00 111.78 ? 73  ALA C CA  1 
ATOM   2229 C C   . ALA C 2 74  ? 110.707 130.133 111.342 1.00 111.78 ? 73  ALA C C   1 
ATOM   2230 O O   . ALA C 2 74  ? 110.675 130.208 112.571 1.00 111.78 ? 73  ALA C O   1 
ATOM   2231 C CB  . ALA C 2 74  ? 111.848 128.191 110.309 1.00 111.78 ? 73  ALA C CB  1 
ATOM   2232 N N   . CYS C 2 75  ? 109.670 130.413 110.561 1.00 128.95 ? 74  CYS C N   1 
ATOM   2233 C CA  . CYS C 2 75  ? 108.359 130.738 111.089 1.00 128.95 ? 74  CYS C CA  1 
ATOM   2234 C C   . CYS C 2 75  ? 107.319 129.949 110.314 1.00 128.95 ? 74  CYS C C   1 
ATOM   2235 O O   . CYS C 2 75  ? 107.508 129.632 109.138 1.00 128.95 ? 74  CYS C O   1 
ATOM   2236 C CB  . CYS C 2 75  ? 108.063 132.239 110.997 1.00 128.95 ? 74  CYS C CB  1 
ATOM   2237 S SG  . CYS C 2 75  ? 107.933 132.879 109.315 1.00 128.95 ? 74  CYS C SG  1 
ATOM   2238 N N   . THR C 2 76  ? 106.221 129.630 110.987 1.00 138.56 ? 75  THR C N   1 
ATOM   2239 C CA  . THR C 2 76  ? 105.166 128.823 110.385 1.00 138.56 ? 75  THR C CA  1 
ATOM   2240 C C   . THR C 2 76  ? 104.324 129.700 109.472 1.00 138.56 ? 75  THR C C   1 
ATOM   2241 O O   . THR C 2 76  ? 103.577 130.563 109.941 1.00 138.56 ? 75  THR C O   1 
ATOM   2242 C CB  . THR C 2 76  ? 104.303 128.183 111.464 1.00 138.56 ? 75  THR C CB  1 
ATOM   2243 O OG1 . THR C 2 76  ? 103.681 129.211 112.243 1.00 138.56 ? 75  THR C OG1 1 
ATOM   2244 C CG2 . THR C 2 76  ? 105.153 127.311 112.369 1.00 138.56 ? 75  THR C CG2 1 
ATOM   2245 N N   . ALA C 2 77  ? 104.452 129.485 108.166 1.00 150.68 ? 76  ALA C N   1 
ATOM   2246 C CA  . ALA C 2 77  ? 103.568 130.137 107.213 1.00 150.68 ? 76  ALA C CA  1 
ATOM   2247 C C   . ALA C 2 77  ? 102.154 129.601 107.377 1.00 150.68 ? 76  ALA C C   1 
ATOM   2248 O O   . ALA C 2 77  ? 101.952 128.419 107.667 1.00 150.68 ? 76  ALA C O   1 
ATOM   2249 C CB  . ALA C 2 77  ? 104.058 129.909 105.785 1.00 150.68 ? 76  ALA C CB  1 
ATOM   2250 N N   . ASN C 2 78  ? 101.170 130.483 107.194 1.00 158.68 ? 77  ASN C N   1 
ATOM   2251 C CA  . ASN C 2 78  ? 99.792  130.114 107.495 1.00 158.68 ? 77  ASN C CA  1 
ATOM   2252 C C   . ASN C 2 78  ? 99.210  129.210 106.417 1.00 158.68 ? 77  ASN C C   1 
ATOM   2253 O O   . ASN C 2 78  ? 98.262  128.460 106.676 1.00 158.68 ? 77  ASN C O   1 
ATOM   2254 C CB  . ASN C 2 78  ? 98.940  131.373 107.657 1.00 158.68 ? 77  ASN C CB  1 
ATOM   2255 C CG  . ASN C 2 78  ? 97.754  131.168 108.584 1.00 158.68 ? 77  ASN C CG  1 
ATOM   2256 O OD1 . ASN C 2 78  ? 97.121  132.133 109.007 1.00 158.68 ? 77  ASN C OD1 1 
ATOM   2257 N ND2 . ASN C 2 78  ? 97.465  129.917 108.929 1.00 158.68 ? 77  ASN C ND2 1 
ATOM   2258 N N   . GLY C 2 79  ? 99.767  129.255 105.210 1.00 157.58 ? 78  GLY C N   1 
ATOM   2259 C CA  . GLY C 2 79  ? 99.241  128.437 104.136 1.00 157.58 ? 78  GLY C CA  1 
ATOM   2260 C C   . GLY C 2 79  ? 99.626  126.975 104.233 1.00 157.58 ? 78  GLY C C   1 
ATOM   2261 O O   . GLY C 2 79  ? 99.056  126.134 103.534 1.00 157.58 ? 78  GLY C O   1 
ATOM   2262 N N   . SER C 2 80  ? 100.584 126.646 105.090 1.00 152.49 ? 79  SER C N   1 
ATOM   2263 C CA  . SER C 2 80  ? 101.089 125.288 105.205 1.00 152.49 ? 79  SER C CA  1 
ATOM   2264 C C   . SER C 2 80  ? 101.085 124.843 106.659 1.00 152.49 ? 79  SER C C   1 
ATOM   2265 O O   . SER C 2 80  ? 100.965 125.664 107.572 1.00 152.49 ? 79  SER C O   1 
ATOM   2266 C CB  . SER C 2 80  ? 102.502 125.184 104.636 1.00 152.49 ? 79  SER C CB  1 
ATOM   2267 O OG  . SER C 2 80  ? 103.412 125.939 105.416 1.00 152.49 ? 79  SER C OG  1 
ATOM   2268 N N   . CYS C 2 81  ? 101.214 123.532 106.863 1.00 150.58 ? 80  CYS C N   1 
ATOM   2269 C CA  . CYS C 2 81  ? 101.314 123.000 108.217 1.00 150.58 ? 80  CYS C CA  1 
ATOM   2270 C C   . CYS C 2 81  ? 102.766 122.899 108.662 1.00 150.58 ? 80  CYS C C   1 
ATOM   2271 O O   . CYS C 2 81  ? 103.086 123.166 109.826 1.00 150.58 ? 80  CYS C O   1 
ATOM   2272 C CB  . CYS C 2 81  ? 100.638 121.634 108.288 1.00 150.58 ? 80  CYS C CB  1 
ATOM   2273 S SG  . CYS C 2 81  ? 101.431 120.376 107.271 1.00 150.58 ? 80  CYS C SG  1 
ATOM   2274 N N   . ASP C 2 82  ? 103.655 122.512 107.755 1.00 148.45 ? 81  ASP C N   1 
ATOM   2275 C CA  . ASP C 2 82  ? 105.062 122.376 108.095 1.00 148.45 ? 81  ASP C CA  1 
ATOM   2276 C C   . ASP C 2 82  ? 105.731 123.746 108.182 1.00 148.45 ? 81  ASP C C   1 
ATOM   2277 O O   . ASP C 2 82  ? 105.336 124.675 107.473 1.00 148.45 ? 81  ASP C O   1 
ATOM   2278 C CB  . ASP C 2 82  ? 105.780 121.502 107.070 1.00 148.45 ? 81  ASP C CB  1 
ATOM   2279 C CG  . ASP C 2 82  ? 105.570 121.967 105.635 1.00 148.45 ? 81  ASP C CG  1 
ATOM   2280 O OD1 . ASP C 2 82  ? 104.735 122.860 105.386 1.00 148.45 ? 81  ASP C OD1 1 
ATOM   2281 O OD2 . ASP C 2 82  ? 106.255 121.432 104.740 1.00 148.45 ? 81  ASP C OD2 1 
ATOM   2282 N N   . PRO C 2 83  ? 106.719 123.914 109.057 1.00 133.18 ? 82  PRO C N   1 
ATOM   2283 C CA  . PRO C 2 83  ? 107.458 125.177 109.082 1.00 133.18 ? 82  PRO C CA  1 
ATOM   2284 C C   . PRO C 2 83  ? 108.414 125.266 107.905 1.00 133.18 ? 82  PRO C C   1 
ATOM   2285 O O   . PRO C 2 83  ? 108.958 124.262 107.445 1.00 133.18 ? 82  PRO C O   1 
ATOM   2286 C CB  . PRO C 2 83  ? 108.209 125.119 110.414 1.00 133.18 ? 82  PRO C CB  1 
ATOM   2287 C CG  . PRO C 2 83  ? 108.372 123.674 110.677 1.00 133.18 ? 82  PRO C CG  1 
ATOM   2288 C CD  . PRO C 2 83  ? 107.139 123.012 110.141 1.00 133.18 ? 82  PRO C CD  1 
ATOM   2289 N N   . SER C 2 84  ? 108.609 126.484 107.414 1.00 121.53 ? 83  SER C N   1 
ATOM   2290 C CA  . SER C 2 84  ? 109.463 126.740 106.265 1.00 121.53 ? 83  SER C CA  1 
ATOM   2291 C C   . SER C 2 84  ? 110.589 127.679 106.662 1.00 121.53 ? 83  SER C C   1 
ATOM   2292 O O   . SER C 2 84  ? 110.377 128.631 107.417 1.00 121.53 ? 83  SER C O   1 
ATOM   2293 C CB  . SER C 2 84  ? 108.668 127.349 105.114 1.00 121.53 ? 83  SER C CB  1 
ATOM   2294 O OG  . SER C 2 84  ? 108.211 128.644 105.458 1.00 121.53 ? 83  SER C OG  1 
ATOM   2295 N N   . VAL C 2 85  ? 111.779 127.420 106.129 1.00 109.54 ? 84  VAL C N   1 
ATOM   2296 C CA  . VAL C 2 85  ? 112.953 128.192 106.506 1.00 109.54 ? 84  VAL C CA  1 
ATOM   2297 C C   . VAL C 2 85  ? 112.922 129.539 105.800 1.00 109.54 ? 84  VAL C C   1 
ATOM   2298 O O   . VAL C 2 85  ? 112.749 129.613 104.578 1.00 109.54 ? 84  VAL C O   1 
ATOM   2299 C CB  . VAL C 2 85  ? 114.229 127.419 106.158 1.00 109.54 ? 84  VAL C CB  1 
ATOM   2300 C CG1 . VAL C 2 85  ? 115.430 128.171 106.641 1.00 109.54 ? 84  VAL C CG1 1 
ATOM   2301 C CG2 . VAL C 2 85  ? 114.181 126.038 106.753 1.00 109.54 ? 84  VAL C CG2 1 
ATOM   2302 N N   . THR C 2 86  ? 113.098 130.613 106.566 1.00 109.17 ? 85  THR C N   1 
ATOM   2303 C CA  . THR C 2 86  ? 113.074 131.961 106.018 1.00 109.17 ? 85  THR C CA  1 
ATOM   2304 C C   . THR C 2 86  ? 114.466 132.515 105.756 1.00 109.17 ? 85  THR C C   1 
ATOM   2305 O O   . THR C 2 86  ? 114.741 133.003 104.658 1.00 109.17 ? 85  THR C O   1 
ATOM   2306 C CB  . THR C 2 86  ? 112.333 132.900 106.968 1.00 109.17 ? 85  THR C CB  1 
ATOM   2307 O OG1 . THR C 2 86  ? 113.048 132.975 108.204 1.00 109.17 ? 85  THR C OG1 1 
ATOM   2308 C CG2 . THR C 2 86  ? 110.941 132.379 107.233 1.00 109.17 ? 85  THR C CG2 1 
ATOM   2309 N N   . ARG C 2 87  ? 115.352 132.454 106.744 1.00 103.50 ? 86  ARG C N   1 
ATOM   2310 C CA  . ARG C 2 87  ? 116.650 133.094 106.623 1.00 103.50 ? 86  ARG C CA  1 
ATOM   2311 C C   . ARG C 2 87  ? 117.671 132.346 107.465 1.00 103.50 ? 86  ARG C C   1 
ATOM   2312 O O   . ARG C 2 87  ? 117.324 131.575 108.365 1.00 103.50 ? 86  ARG C O   1 
ATOM   2313 C CB  . ARG C 2 87  ? 116.568 134.563 107.037 1.00 103.50 ? 86  ARG C CB  1 
ATOM   2314 C CG  . ARG C 2 87  ? 116.162 134.754 108.478 1.00 103.50 ? 86  ARG C CG  1 
ATOM   2315 C CD  . ARG C 2 87  ? 115.951 136.215 108.803 1.00 103.50 ? 86  ARG C CD  1 
ATOM   2316 N NE  . ARG C 2 87  ? 115.648 136.412 110.216 1.00 103.50 ? 86  ARG C NE  1 
ATOM   2317 C CZ  . ARG C 2 87  ? 114.423 136.384 110.727 1.00 103.50 ? 86  ARG C CZ  1 
ATOM   2318 N NH1 . ARG C 2 87  ? 113.381 136.176 109.938 1.00 103.50 ? 86  ARG C NH1 1 
ATOM   2319 N NH2 . ARG C 2 87  ? 114.240 136.570 112.025 1.00 103.50 ? 86  ARG C NH2 1 
ATOM   2320 N N   . GLN C 2 88  ? 118.938 132.573 107.149 1.00 99.35  ? 87  GLN C N   1 
ATOM   2321 C CA  . GLN C 2 88  ? 120.054 131.975 107.861 1.00 99.35  ? 87  GLN C CA  1 
ATOM   2322 C C   . GLN C 2 88  ? 120.904 133.071 108.483 1.00 99.35  ? 87  GLN C C   1 
ATOM   2323 O O   . GLN C 2 88  ? 120.588 134.257 108.410 1.00 99.35  ? 87  GLN C O   1 
ATOM   2324 C CB  . GLN C 2 88  ? 120.929 131.121 106.940 1.00 99.35  ? 87  GLN C CB  1 
ATOM   2325 C CG  . GLN C 2 88  ? 120.344 129.797 106.520 1.00 99.35  ? 87  GLN C CG  1 
ATOM   2326 C CD  . GLN C 2 88  ? 119.319 129.951 105.438 1.00 99.35  ? 87  GLN C CD  1 
ATOM   2327 O OE1 . GLN C 2 88  ? 118.163 129.597 105.611 1.00 99.35  ? 87  GLN C OE1 1 
ATOM   2328 N NE2 . GLN C 2 88  ? 119.734 130.501 104.310 1.00 99.35  ? 87  GLN C NE2 1 
ATOM   2329 N N   . ALA C 2 89  ? 121.991 132.650 109.114 1.00 92.50  ? 88  ALA C N   1 
ATOM   2330 C CA  . ALA C 2 89  ? 123.048 133.566 109.538 1.00 92.50  ? 88  ALA C CA  1 
ATOM   2331 C C   . ALA C 2 89  ? 124.373 132.838 109.330 1.00 92.50  ? 88  ALA C C   1 
ATOM   2332 O O   . ALA C 2 89  ? 124.853 132.137 110.220 1.00 92.50  ? 88  ALA C O   1 
ATOM   2333 C CB  . ALA C 2 89  ? 122.857 134.000 110.980 1.00 92.50  ? 88  ALA C CB  1 
ATOM   2334 N N   . TYR C 2 90  ? 124.963 133.013 108.156 1.00 89.45  ? 89  TYR C N   1 
ATOM   2335 C CA  . TYR C 2 90  ? 126.183 132.299 107.828 1.00 89.45  ? 89  TYR C CA  1 
ATOM   2336 C C   . TYR C 2 90  ? 127.378 132.934 108.518 1.00 89.45  ? 89  TYR C C   1 
ATOM   2337 O O   . TYR C 2 90  ? 127.386 134.130 108.816 1.00 89.45  ? 89  TYR C O   1 
ATOM   2338 C CB  . TYR C 2 90  ? 126.414 132.294 106.323 1.00 89.45  ? 89  TYR C CB  1 
ATOM   2339 C CG  . TYR C 2 90  ? 125.363 131.545 105.558 1.00 89.45  ? 89  TYR C CG  1 
ATOM   2340 C CD1 . TYR C 2 90  ? 125.396 130.165 105.475 1.00 89.45  ? 89  TYR C CD1 1 
ATOM   2341 C CD2 . TYR C 2 90  ? 124.340 132.220 104.914 1.00 89.45  ? 89  TYR C CD2 1 
ATOM   2342 C CE1 . TYR C 2 90  ? 124.438 129.475 104.775 1.00 89.45  ? 89  TYR C CE1 1 
ATOM   2343 C CE2 . TYR C 2 90  ? 123.378 131.542 104.211 1.00 89.45  ? 89  TYR C CE2 1 
ATOM   2344 C CZ  . TYR C 2 90  ? 123.430 130.170 104.145 1.00 89.45  ? 89  TYR C CZ  1 
ATOM   2345 O OH  . TYR C 2 90  ? 122.468 129.485 103.443 1.00 89.45  ? 89  TYR C OH  1 
ATOM   2346 N N   . ALA C 2 91  ? 128.396 132.114 108.763 1.00 85.31  ? 90  ALA C N   1 
ATOM   2347 C CA  . ALA C 2 91  ? 129.678 132.595 109.250 1.00 85.31  ? 90  ALA C CA  1 
ATOM   2348 C C   . ALA C 2 91  ? 130.724 131.553 108.909 1.00 85.31  ? 90  ALA C C   1 
ATOM   2349 O O   . ALA C 2 91  ? 130.410 130.368 108.818 1.00 85.31  ? 90  ALA C O   1 
ATOM   2350 C CB  . ALA C 2 91  ? 129.657 132.839 110.758 1.00 85.31  ? 90  ALA C CB  1 
ATOM   2351 N N   . ASP C 2 92  ? 131.965 131.997 108.730 1.00 89.14  ? 91  ASP C N   1 
ATOM   2352 C CA  . ASP C 2 92  ? 133.057 131.067 108.483 1.00 89.14  ? 91  ASP C CA  1 
ATOM   2353 C C   . ASP C 2 92  ? 134.385 131.719 108.822 1.00 89.14  ? 91  ASP C C   1 
ATOM   2354 O O   . ASP C 2 92  ? 134.554 132.925 108.657 1.00 89.14  ? 91  ASP C O   1 
ATOM   2355 C CB  . ASP C 2 92  ? 133.063 130.575 107.033 1.00 89.14  ? 91  ASP C CB  1 
ATOM   2356 C CG  . ASP C 2 92  ? 132.968 131.699 106.043 1.00 89.14  ? 91  ASP C CG  1 
ATOM   2357 O OD1 . ASP C 2 92  ? 132.718 132.844 106.470 1.00 89.14  ? 91  ASP C OD1 1 
ATOM   2358 O OD2 . ASP C 2 92  ? 133.156 131.441 104.835 1.00 89.14  ? 91  ASP C OD2 1 
ATOM   2359 N N   . VAL C 2 93  ? 135.307 130.911 109.323 1.00 88.35  ? 92  VAL C N   1 
ATOM   2360 C CA  . VAL C 2 93  ? 136.675 131.332 109.567 1.00 88.35  ? 92  VAL C CA  1 
ATOM   2361 C C   . VAL C 2 93  ? 137.563 130.498 108.658 1.00 88.35  ? 92  VAL C C   1 
ATOM   2362 O O   . VAL C 2 93  ? 137.230 129.358 108.313 1.00 88.35  ? 92  VAL C O   1 
ATOM   2363 C CB  . VAL C 2 93  ? 137.078 131.192 111.055 1.00 88.35  ? 92  VAL C CB  1 
ATOM   2364 C CG1 . VAL C 2 93  ? 136.001 131.763 111.934 1.00 88.35  ? 92  VAL C CG1 1 
ATOM   2365 C CG2 . VAL C 2 93  ? 137.341 129.778 111.447 1.00 88.35  ? 92  VAL C CG2 1 
ATOM   2366 N N   . THR C 2 94  ? 138.657 131.103 108.193 1.00 88.42  ? 93  THR C N   1 
ATOM   2367 C CA  . THR C 2 94  ? 139.633 130.419 107.340 1.00 88.42  ? 93  THR C CA  1 
ATOM   2368 C C   . THR C 2 94  ? 141.027 130.800 107.821 1.00 88.42  ? 93  THR C C   1 
ATOM   2369 O O   . THR C 2 94  ? 141.526 131.880 107.498 1.00 88.42  ? 93  THR C O   1 
ATOM   2370 C CB  . THR C 2 94  ? 139.474 130.772 105.863 1.00 88.42  ? 93  THR C CB  1 
ATOM   2371 O OG1 . THR C 2 94  ? 139.536 132.190 105.700 1.00 88.42  ? 93  THR C OG1 1 
ATOM   2372 C CG2 . THR C 2 94  ? 138.178 130.237 105.263 1.00 88.42  ? 93  THR C CG2 1 
ATOM   2373 N N   . PHE C 2 95  ? 141.654 129.909 108.573 1.00 89.44  ? 94  PHE C N   1 
ATOM   2374 C CA  . PHE C 2 95  ? 143.043 130.065 108.962 1.00 89.44  ? 94  PHE C CA  1 
ATOM   2375 C C   . PHE C 2 95  ? 143.944 129.509 107.872 1.00 89.44  ? 94  PHE C C   1 
ATOM   2376 O O   . PHE C 2 95  ? 143.645 128.472 107.275 1.00 89.44  ? 94  PHE C O   1 
ATOM   2377 C CB  . PHE C 2 95  ? 143.315 129.331 110.268 1.00 89.44  ? 94  PHE C CB  1 
ATOM   2378 C CG  . PHE C 2 95  ? 142.533 129.854 111.413 1.00 89.44  ? 94  PHE C CG  1 
ATOM   2379 C CD1 . PHE C 2 95  ? 142.945 130.982 112.081 1.00 89.44  ? 94  PHE C CD1 1 
ATOM   2380 C CD2 . PHE C 2 95  ? 141.380 129.218 111.822 1.00 89.44  ? 94  PHE C CD2 1 
ATOM   2381 C CE1 . PHE C 2 95  ? 142.224 131.476 113.136 1.00 89.44  ? 94  PHE C CE1 1 
ATOM   2382 C CE2 . PHE C 2 95  ? 140.654 129.700 112.881 1.00 89.44  ? 94  PHE C CE2 1 
ATOM   2383 C CZ  . PHE C 2 95  ? 141.074 130.833 113.538 1.00 89.44  ? 94  PHE C CZ  1 
ATOM   2384 N N   . SER C 2 96  ? 145.058 130.191 107.629 1.00 95.86  ? 95  SER C N   1 
ATOM   2385 C CA  . SER C 2 96  ? 146.030 129.759 106.634 1.00 95.86  ? 95  SER C CA  1 
ATOM   2386 C C   . SER C 2 96  ? 147.425 129.883 107.219 1.00 95.86  ? 95  SER C C   1 
ATOM   2387 O O   . SER C 2 96  ? 147.871 130.989 107.532 1.00 95.86  ? 95  SER C O   1 
ATOM   2388 C CB  . SER C 2 96  ? 145.911 130.584 105.356 1.00 95.86  ? 95  SER C CB  1 
ATOM   2389 O OG  . SER C 2 96  ? 146.893 130.192 104.419 1.00 95.86  ? 95  SER C OG  1 
ATOM   2390 N N   . PHE C 2 97  ? 148.108 128.758 107.360 1.00 99.74  ? 96  PHE C N   1 
ATOM   2391 C CA  . PHE C 2 97  ? 149.462 128.708 107.882 1.00 99.74  ? 96  PHE C CA  1 
ATOM   2392 C C   . PHE C 2 97  ? 150.398 128.200 106.795 1.00 99.74  ? 96  PHE C C   1 
ATOM   2393 O O   . PHE C 2 97  ? 149.979 127.914 105.673 1.00 99.74  ? 96  PHE C O   1 
ATOM   2394 C CB  . PHE C 2 97  ? 149.521 127.810 109.111 1.00 99.74  ? 96  PHE C CB  1 
ATOM   2395 C CG  . PHE C 2 97  ? 148.617 128.244 110.214 1.00 99.74  ? 96  PHE C CG  1 
ATOM   2396 C CD1 . PHE C 2 97  ? 148.971 129.281 111.050 1.00 99.74  ? 96  PHE C CD1 1 
ATOM   2397 C CD2 . PHE C 2 97  ? 147.413 127.604 110.420 1.00 99.74  ? 96  PHE C CD2 1 
ATOM   2398 C CE1 . PHE C 2 97  ? 148.137 129.674 112.072 1.00 99.74  ? 96  PHE C CE1 1 
ATOM   2399 C CE2 . PHE C 2 97  ? 146.577 127.992 111.436 1.00 99.74  ? 96  PHE C CE2 1 
ATOM   2400 C CZ  . PHE C 2 97  ? 146.940 129.027 112.264 1.00 99.74  ? 96  PHE C CZ  1 
ATOM   2401 N N   . THR C 2 98  ? 151.674 128.077 107.133 1.00 105.97 ? 97  THR C N   1 
ATOM   2402 C CA  . THR C 2 98  ? 152.673 127.547 106.216 1.00 105.97 ? 97  THR C CA  1 
ATOM   2403 C C   . THR C 2 98  ? 153.292 126.287 106.803 1.00 105.97 ? 97  THR C C   1 
ATOM   2404 O O   . THR C 2 98  ? 152.928 125.841 107.891 1.00 105.97 ? 97  THR C O   1 
ATOM   2405 C CB  . THR C 2 98  ? 153.759 128.579 105.923 1.00 105.97 ? 97  THR C CB  1 
ATOM   2406 O OG1 . THR C 2 98  ? 154.420 128.923 107.143 1.00 105.97 ? 97  THR C OG1 1 
ATOM   2407 C CG2 . THR C 2 98  ? 153.159 129.824 105.307 1.00 105.97 ? 97  THR C CG2 1 
ATOM   2408 N N   . GLN C 2 99  ? 154.244 125.715 106.060 1.00 112.67 ? 98  GLN C N   1 
ATOM   2409 C CA  . GLN C 2 99  ? 154.913 124.498 106.510 1.00 112.67 ? 98  GLN C CA  1 
ATOM   2410 C C   . GLN C 2 99  ? 155.765 124.739 107.744 1.00 112.67 ? 98  GLN C C   1 
ATOM   2411 O O   . GLN C 2 99  ? 155.919 123.837 108.572 1.00 112.67 ? 98  GLN C O   1 
ATOM   2412 C CB  . GLN C 2 99  ? 155.795 123.918 105.405 1.00 112.67 ? 98  GLN C CB  1 
ATOM   2413 C CG  . GLN C 2 99  ? 155.080 123.103 104.346 1.00 112.67 ? 98  GLN C CG  1 
ATOM   2414 C CD  . GLN C 2 99  ? 154.277 123.946 103.388 1.00 112.67 ? 98  GLN C CD  1 
ATOM   2415 O OE1 . GLN C 2 99  ? 153.064 123.784 103.269 1.00 112.67 ? 98  GLN C OE1 1 
ATOM   2416 N NE2 . GLN C 2 99  ? 154.950 124.851 102.691 1.00 112.67 ? 98  GLN C NE2 1 
ATOM   2417 N N   . TYR C 2 100 ? 156.320 125.937 107.889 1.00 110.99 ? 99  TYR C N   1 
ATOM   2418 C CA  . TYR C 2 100 ? 157.266 126.222 108.956 1.00 110.99 ? 99  TYR C CA  1 
ATOM   2419 C C   . TYR C 2 100 ? 156.614 126.927 110.134 1.00 110.99 ? 99  TYR C C   1 
ATOM   2420 O O   . TYR C 2 100 ? 157.303 127.597 110.907 1.00 110.99 ? 99  TYR C O   1 
ATOM   2421 C CB  . TYR C 2 100 ? 158.425 127.058 108.418 1.00 110.99 ? 99  TYR C CB  1 
ATOM   2422 C CG  . TYR C 2 100 ? 159.324 126.331 107.444 1.00 110.99 ? 99  TYR C CG  1 
ATOM   2423 C CD1 . TYR C 2 100 ? 159.323 124.946 107.361 1.00 110.99 ? 99  TYR C CD1 1 
ATOM   2424 C CD2 . TYR C 2 100 ? 160.170 127.036 106.603 1.00 110.99 ? 99  TYR C CD2 1 
ATOM   2425 C CE1 . TYR C 2 100 ? 160.138 124.288 106.472 1.00 110.99 ? 99  TYR C CE1 1 
ATOM   2426 C CE2 . TYR C 2 100 ? 160.991 126.384 105.711 1.00 110.99 ? 99  TYR C CE2 1 
ATOM   2427 C CZ  . TYR C 2 100 ? 160.970 125.011 105.651 1.00 110.99 ? 99  TYR C CZ  1 
ATOM   2428 O OH  . TYR C 2 100 ? 161.787 124.360 104.762 1.00 110.99 ? 99  TYR C OH  1 
ATOM   2429 N N   . SER C 2 101 ? 155.304 126.795 110.286 1.00 109.00 ? 100 SER C N   1 
ATOM   2430 C CA  . SER C 2 101 ? 154.605 127.445 111.381 1.00 109.00 ? 100 SER C CA  1 
ATOM   2431 C C   . SER C 2 101 ? 154.811 126.649 112.658 1.00 109.00 ? 100 SER C C   1 
ATOM   2432 O O   . SER C 2 101 ? 154.574 125.440 112.687 1.00 109.00 ? 100 SER C O   1 
ATOM   2433 C CB  . SER C 2 101 ? 153.120 127.552 111.058 1.00 109.00 ? 100 SER C CB  1 
ATOM   2434 O OG  . SER C 2 101 ? 152.913 128.307 109.879 1.00 109.00 ? 100 SER C OG  1 
ATOM   2435 N N   . THR C 2 102 ? 155.242 127.320 113.719 1.00 109.07 ? 101 THR C N   1 
ATOM   2436 C CA  . THR C 2 102 ? 155.441 126.625 114.979 1.00 109.07 ? 101 THR C CA  1 
ATOM   2437 C C   . THR C 2 102 ? 154.104 126.420 115.683 1.00 109.07 ? 101 THR C C   1 
ATOM   2438 O O   . THR C 2 102 ? 153.047 126.832 115.207 1.00 109.07 ? 101 THR C O   1 
ATOM   2439 C CB  . THR C 2 102 ? 156.403 127.395 115.874 1.00 109.07 ? 101 THR C CB  1 
ATOM   2440 O OG1 . THR C 2 102 ? 155.823 128.656 116.217 1.00 109.07 ? 101 THR C OG1 1 
ATOM   2441 C CG2 . THR C 2 102 ? 157.713 127.632 115.157 1.00 109.07 ? 101 THR C CG2 1 
ATOM   2442 N N   . ASP C 2 103 ? 154.150 125.780 116.847 1.00 113.61 ? 102 ASP C N   1 
ATOM   2443 C CA  . ASP C 2 103 ? 152.930 125.502 117.594 1.00 113.61 ? 102 ASP C CA  1 
ATOM   2444 C C   . ASP C 2 103 ? 152.421 126.757 118.293 1.00 113.61 ? 102 ASP C C   1 
ATOM   2445 O O   . ASP C 2 103 ? 151.222 127.067 118.239 1.00 113.61 ? 102 ASP C O   1 
ATOM   2446 C CB  . ASP C 2 103 ? 153.198 124.389 118.608 1.00 113.61 ? 102 ASP C CB  1 
ATOM   2447 C CG  . ASP C 2 103 ? 151.929 123.783 119.180 1.00 113.61 ? 102 ASP C CG  1 
ATOM   2448 O OD1 . ASP C 2 103 ? 150.819 124.198 118.793 1.00 113.61 ? 102 ASP C OD1 1 
ATOM   2449 O OD2 . ASP C 2 103 ? 152.050 122.875 120.030 1.00 113.61 ? 102 ASP C OD2 1 
ATOM   2450 N N   . GLU C 2 104 ? 153.329 127.475 118.958 1.00 115.54 ? 103 GLU C N   1 
ATOM   2451 C CA  . GLU C 2 104 ? 152.968 128.681 119.695 1.00 115.54 ? 103 GLU C CA  1 
ATOM   2452 C C   . GLU C 2 104 ? 152.426 129.755 118.766 1.00 115.54 ? 103 GLU C C   1 
ATOM   2453 O O   . GLU C 2 104 ? 151.435 130.426 119.084 1.00 115.54 ? 103 GLU C O   1 
ATOM   2454 C CB  . GLU C 2 104 ? 154.191 129.202 120.446 1.00 115.54 ? 103 GLU C CB  1 
ATOM   2455 C CG  . GLU C 2 104 ? 153.935 130.447 121.264 1.00 115.54 ? 103 GLU C CG  1 
ATOM   2456 C CD  . GLU C 2 104 ? 153.079 130.176 122.479 1.00 115.54 ? 103 GLU C CD  1 
ATOM   2457 O OE1 . GLU C 2 104 ? 153.138 129.045 123.002 1.00 115.54 ? 103 GLU C OE1 1 
ATOM   2458 O OE2 . GLU C 2 104 ? 152.345 131.090 122.907 1.00 115.54 ? 103 GLU C OE2 1 
ATOM   2459 N N   . GLU C 2 105 ? 153.044 129.904 117.597 1.00 111.57 ? 104 GLU C N   1 
ATOM   2460 C CA  . GLU C 2 105 ? 152.618 130.921 116.652 1.00 111.57 ? 104 GLU C CA  1 
ATOM   2461 C C   . GLU C 2 105 ? 151.282 130.573 116.014 1.00 111.57 ? 104 GLU C C   1 
ATOM   2462 O O   . GLU C 2 105 ? 150.548 131.479 115.612 1.00 111.57 ? 104 GLU C O   1 
ATOM   2463 C CB  . GLU C 2 105 ? 153.708 131.110 115.600 1.00 111.57 ? 104 GLU C CB  1 
ATOM   2464 C CG  . GLU C 2 105 ? 153.631 132.400 114.817 1.00 111.57 ? 104 GLU C CG  1 
ATOM   2465 C CD  . GLU C 2 105 ? 152.785 132.285 113.579 1.00 111.57 ? 104 GLU C CD  1 
ATOM   2466 O OE1 . GLU C 2 105 ? 152.705 131.172 113.023 1.00 111.57 ? 104 GLU C OE1 1 
ATOM   2467 O OE2 . GLU C 2 105 ? 152.202 133.307 113.165 1.00 111.57 ? 104 GLU C OE2 1 
ATOM   2468 N N   . ARG C 2 106 ? 150.934 129.289 115.939 1.00 104.36 ? 105 ARG C N   1 
ATOM   2469 C CA  . ARG C 2 106 ? 149.590 128.939 115.500 1.00 104.36 ? 105 ARG C CA  1 
ATOM   2470 C C   . ARG C 2 106 ? 148.566 129.192 116.592 1.00 104.36 ? 105 ARG C C   1 
ATOM   2471 O O   . ARG C 2 106 ? 147.458 129.651 116.301 1.00 104.36 ? 105 ARG C O   1 
ATOM   2472 C CB  . ARG C 2 106 ? 149.521 127.480 115.062 1.00 104.36 ? 105 ARG C CB  1 
ATOM   2473 C CG  . ARG C 2 106 ? 150.166 127.194 113.732 1.00 104.36 ? 105 ARG C CG  1 
ATOM   2474 C CD  . ARG C 2 106 ? 149.833 125.795 113.278 1.00 104.36 ? 105 ARG C CD  1 
ATOM   2475 N NE  . ARG C 2 106 ? 150.361 124.801 114.202 1.00 104.36 ? 105 ARG C NE  1 
ATOM   2476 C CZ  . ARG C 2 106 ? 151.568 124.265 114.098 1.00 104.36 ? 105 ARG C CZ  1 
ATOM   2477 N NH1 . ARG C 2 106 ? 152.361 124.623 113.104 1.00 104.36 ? 105 ARG C NH1 1 
ATOM   2478 N NH2 . ARG C 2 106 ? 151.977 123.372 114.984 1.00 104.36 ? 105 ARG C NH2 1 
ATOM   2479 N N   . ALA C 2 107 ? 148.908 128.894 117.848 1.00 104.71 ? 106 ALA C N   1 
ATOM   2480 C CA  . ALA C 2 107 ? 147.933 129.063 118.924 1.00 104.71 ? 106 ALA C CA  1 
ATOM   2481 C C   . ALA C 2 107 ? 147.654 130.529 119.208 1.00 104.71 ? 106 ALA C C   1 
ATOM   2482 O O   . ALA C 2 107 ? 146.544 130.878 119.646 1.00 104.71 ? 106 ALA C O   1 
ATOM   2483 C CB  . ALA C 2 107 ? 148.425 128.372 120.190 1.00 104.71 ? 106 ALA C CB  1 
ATOM   2484 N N   . PHE C 2 108 ? 148.652 131.380 118.960 1.00 98.17  ? 107 PHE C N   1 
ATOM   2485 C CA  . PHE C 2 108 ? 148.522 132.818 119.159 1.00 98.17  ? 107 PHE C CA  1 
ATOM   2486 C C   . PHE C 2 108 ? 147.395 133.396 118.318 1.00 98.17  ? 107 PHE C C   1 
ATOM   2487 O O   . PHE C 2 108 ? 146.621 134.230 118.800 1.00 98.17  ? 107 PHE C O   1 
ATOM   2488 C CB  . PHE C 2 108 ? 149.848 133.479 118.804 1.00 98.17  ? 107 PHE C CB  1 
ATOM   2489 C CG  . PHE C 2 108 ? 149.907 134.938 119.094 1.00 98.17  ? 107 PHE C CG  1 
ATOM   2490 C CD1 . PHE C 2 108 ? 150.164 135.388 120.374 1.00 98.17  ? 107 PHE C CD1 1 
ATOM   2491 C CD2 . PHE C 2 108 ? 149.735 135.861 118.082 1.00 98.17  ? 107 PHE C CD2 1 
ATOM   2492 C CE1 . PHE C 2 108 ? 150.243 136.729 120.639 1.00 98.17  ? 107 PHE C CE1 1 
ATOM   2493 C CE2 . PHE C 2 108 ? 149.804 137.204 118.342 1.00 98.17  ? 107 PHE C CE2 1 
ATOM   2494 C CZ  . PHE C 2 108 ? 150.057 137.642 119.625 1.00 98.17  ? 107 PHE C CZ  1 
ATOM   2495 N N   . VAL C 2 109 ? 147.250 132.911 117.083 1.00 99.48  ? 108 VAL C N   1 
ATOM   2496 C CA  . VAL C 2 109 ? 146.258 133.452 116.161 1.00 99.48  ? 108 VAL C CA  1 
ATOM   2497 C C   . VAL C 2 109 ? 144.850 133.122 116.630 1.00 99.48  ? 108 VAL C C   1 
ATOM   2498 O O   . VAL C 2 109 ? 143.985 134.005 116.706 1.00 99.48  ? 108 VAL C O   1 
ATOM   2499 C CB  . VAL C 2 109 ? 146.507 132.923 114.741 1.00 99.48  ? 108 VAL C CB  1 
ATOM   2500 C CG1 . VAL C 2 109 ? 145.406 133.365 113.813 1.00 99.48  ? 108 VAL C CG1 1 
ATOM   2501 C CG2 . VAL C 2 109 ? 147.834 133.411 114.243 1.00 99.48  ? 108 VAL C CG2 1 
ATOM   2502 N N   . ARG C 2 110 ? 144.602 131.854 116.966 1.00 101.06 ? 109 ARG C N   1 
ATOM   2503 C CA  . ARG C 2 110 ? 143.252 131.479 117.359 1.00 101.06 ? 109 ARG C CA  1 
ATOM   2504 C C   . ARG C 2 110 ? 142.882 132.057 118.716 1.00 101.06 ? 109 ARG C C   1 
ATOM   2505 O O   . ARG C 2 110 ? 141.721 132.419 118.922 1.00 101.06 ? 109 ARG C O   1 
ATOM   2506 C CB  . ARG C 2 110 ? 143.065 129.962 117.366 1.00 101.06 ? 109 ARG C CB  1 
ATOM   2507 C CG  . ARG C 2 110 ? 143.849 129.243 118.415 1.00 101.06 ? 109 ARG C CG  1 
ATOM   2508 C CD  . ARG C 2 110 ? 143.381 127.838 118.614 1.00 101.06 ? 109 ARG C CD  1 
ATOM   2509 N NE  . ARG C 2 110 ? 144.168 127.203 119.661 1.00 101.06 ? 109 ARG C NE  1 
ATOM   2510 C CZ  . ARG C 2 110 ? 143.897 127.308 120.954 1.00 101.06 ? 109 ARG C CZ  1 
ATOM   2511 N NH1 . ARG C 2 110 ? 142.849 128.007 121.363 1.00 101.06 ? 109 ARG C NH1 1 
ATOM   2512 N NH2 . ARG C 2 110 ? 144.664 126.698 121.843 1.00 101.06 ? 109 ARG C NH2 1 
ATOM   2513 N N   . THR C 2 111 ? 143.846 132.234 119.625 1.00 102.55 ? 110 THR C N   1 
ATOM   2514 C CA  . THR C 2 111 ? 143.452 132.795 120.906 1.00 102.55 ? 110 THR C CA  1 
ATOM   2515 C C   . THR C 2 111 ? 143.244 134.296 120.797 1.00 102.55 ? 110 THR C C   1 
ATOM   2516 O O   . THR C 2 111 ? 142.346 134.841 121.452 1.00 102.55 ? 110 THR C O   1 
ATOM   2517 C CB  . THR C 2 111 ? 144.486 132.458 121.969 1.00 102.55 ? 110 THR C CB  1 
ATOM   2518 O OG1 . THR C 2 111 ? 144.789 131.064 121.885 1.00 102.55 ? 110 THR C OG1 1 
ATOM   2519 C CG2 . THR C 2 111 ? 143.897 132.691 123.333 1.00 102.55 ? 110 THR C CG2 1 
ATOM   2520 N N   . GLU C 2 112 ? 144.015 134.957 119.927 1.00 101.39 ? 111 GLU C N   1 
ATOM   2521 C CA  . GLU C 2 112 ? 143.798 136.370 119.652 1.00 101.39 ? 111 GLU C CA  1 
ATOM   2522 C C   . GLU C 2 112 ? 142.438 136.608 119.024 1.00 101.39 ? 111 GLU C C   1 
ATOM   2523 O O   . GLU C 2 112 ? 141.717 137.524 119.429 1.00 101.39 ? 111 GLU C O   1 
ATOM   2524 C CB  . GLU C 2 112 ? 144.901 136.890 118.740 1.00 101.39 ? 111 GLU C CB  1 
ATOM   2525 C CG  . GLU C 2 112 ? 144.796 138.354 118.420 1.00 101.39 ? 111 GLU C CG  1 
ATOM   2526 C CD  . GLU C 2 112 ? 145.948 138.834 117.571 1.00 101.39 ? 111 GLU C CD  1 
ATOM   2527 O OE1 . GLU C 2 112 ? 146.823 138.011 117.239 1.00 101.39 ? 111 GLU C OE1 1 
ATOM   2528 O OE2 . GLU C 2 112 ? 145.966 140.024 117.205 1.00 101.39 ? 111 GLU C OE2 1 
ATOM   2529 N N   . LEU C 2 113 ? 142.048 135.760 118.070 1.00 98.99  ? 112 LEU C N   1 
ATOM   2530 C CA  . LEU C 2 113 ? 140.740 135.911 117.441 1.00 98.99  ? 112 LEU C CA  1 
ATOM   2531 C C   . LEU C 2 113 ? 139.612 135.598 118.416 1.00 98.99  ? 112 LEU C C   1 
ATOM   2532 O O   . LEU C 2 113 ? 138.595 136.306 118.448 1.00 98.99  ? 112 LEU C O   1 
ATOM   2533 C CB  . LEU C 2 113 ? 140.648 135.011 116.215 1.00 98.99  ? 112 LEU C CB  1 
ATOM   2534 C CG  . LEU C 2 113 ? 139.340 135.087 115.441 1.00 98.99  ? 112 LEU C CG  1 
ATOM   2535 C CD1 . LEU C 2 113 ? 139.134 136.490 114.940 1.00 98.99  ? 112 LEU C CD1 1 
ATOM   2536 C CD2 . LEU C 2 113 ? 139.372 134.117 114.289 1.00 98.99  ? 112 LEU C CD2 1 
ATOM   2537 N N   . ALA C 2 114 ? 139.797 134.572 119.247 1.00 99.98  ? 113 ALA C N   1 
ATOM   2538 C CA  . ALA C 2 114 ? 138.752 134.159 120.172 1.00 99.98  ? 113 ALA C CA  1 
ATOM   2539 C C   . ALA C 2 114 ? 138.530 135.190 121.266 1.00 99.98  ? 113 ALA C C   1 
ATOM   2540 O O   . ALA C 2 114 ? 137.393 135.412 121.691 1.00 99.98  ? 113 ALA C O   1 
ATOM   2541 C CB  . ALA C 2 114 ? 139.110 132.808 120.777 1.00 99.98  ? 113 ALA C CB  1 
ATOM   2542 N N   . ALA C 2 115 ? 139.594 135.834 121.734 1.00 100.33 ? 114 ALA C N   1 
ATOM   2543 C CA  . ALA C 2 115 ? 139.400 136.884 122.719 1.00 100.33 ? 114 ALA C CA  1 
ATOM   2544 C C   . ALA C 2 115 ? 139.032 138.211 122.084 1.00 100.33 ? 114 ALA C C   1 
ATOM   2545 O O   . ALA C 2 115 ? 138.462 139.068 122.763 1.00 100.33 ? 114 ALA C O   1 
ATOM   2546 C CB  . ALA C 2 115 ? 140.648 137.053 123.576 1.00 100.33 ? 114 ALA C CB  1 
ATOM   2547 N N   . LEU C 2 116 ? 139.330 138.405 120.802 1.00 96.62  ? 115 LEU C N   1 
ATOM   2548 C CA  . LEU C 2 116 ? 138.949 139.642 120.146 1.00 96.62  ? 115 LEU C CA  1 
ATOM   2549 C C   . LEU C 2 116 ? 137.490 139.638 119.727 1.00 96.62  ? 115 LEU C C   1 
ATOM   2550 O O   . LEU C 2 116 ? 136.906 140.711 119.560 1.00 96.62  ? 115 LEU C O   1 
ATOM   2551 C CB  . LEU C 2 116 ? 139.877 139.883 118.951 1.00 96.62  ? 115 LEU C CB  1 
ATOM   2552 C CG  . LEU C 2 116 ? 139.895 141.215 118.204 1.00 96.62  ? 115 LEU C CG  1 
ATOM   2553 C CD1 . LEU C 2 116 ? 141.301 141.543 117.800 1.00 96.62  ? 115 LEU C CD1 1 
ATOM   2554 C CD2 . LEU C 2 116 ? 139.068 141.124 116.957 1.00 96.62  ? 115 LEU C CD2 1 
ATOM   2555 N N   . LEU C 2 117 ? 136.878 138.461 119.588 1.00 95.66  ? 116 LEU C N   1 
ATOM   2556 C CA  . LEU C 2 117 ? 135.445 138.418 119.311 1.00 95.66  ? 116 LEU C CA  1 
ATOM   2557 C C   . LEU C 2 117 ? 134.573 138.809 120.499 1.00 95.66  ? 116 LEU C C   1 
ATOM   2558 O O   . LEU C 2 117 ? 133.354 138.898 120.333 1.00 95.66  ? 116 LEU C O   1 
ATOM   2559 C CB  . LEU C 2 117 ? 135.026 137.032 118.839 1.00 95.66  ? 116 LEU C CB  1 
ATOM   2560 C CG  . LEU C 2 117 ? 135.417 136.637 117.424 1.00 95.66  ? 116 LEU C CG  1 
ATOM   2561 C CD1 . LEU C 2 117 ? 135.074 135.190 117.197 1.00 95.66  ? 116 LEU C CD1 1 
ATOM   2562 C CD2 . LEU C 2 117 ? 134.673 137.496 116.443 1.00 95.66  ? 116 LEU C CD2 1 
ATOM   2563 N N   . ALA C 2 118 ? 135.137 139.020 121.686 1.00 95.78  ? 117 ALA C N   1 
ATOM   2564 C CA  . ALA C 2 118 ? 134.364 139.500 122.824 1.00 95.78  ? 117 ALA C CA  1 
ATOM   2565 C C   . ALA C 2 118 ? 134.792 140.892 123.260 1.00 95.78  ? 117 ALA C C   1 
ATOM   2566 O O   . ALA C 2 118 ? 134.472 141.315 124.373 1.00 95.78  ? 117 ALA C O   1 
ATOM   2567 C CB  . ALA C 2 118 ? 134.468 138.527 123.995 1.00 95.78  ? 117 ALA C CB  1 
ATOM   2568 N N   . SER C 2 119 ? 135.510 141.607 122.404 1.00 98.19  ? 118 SER C N   1 
ATOM   2569 C CA  . SER C 2 119 ? 135.962 142.947 122.714 1.00 98.19  ? 118 SER C CA  1 
ATOM   2570 C C   . SER C 2 119 ? 134.782 143.911 122.719 1.00 98.19  ? 118 SER C C   1 
ATOM   2571 O O   . SER C 2 119 ? 133.739 143.625 122.132 1.00 98.19  ? 118 SER C O   1 
ATOM   2572 C CB  . SER C 2 119 ? 136.990 143.397 121.681 1.00 98.19  ? 118 SER C CB  1 
ATOM   2573 O OG  . SER C 2 119 ? 136.360 143.631 120.436 1.00 98.19  ? 118 SER C OG  1 
ATOM   2574 N N   . PRO C 2 120 ? 134.923 145.082 123.349 1.00 101.39 ? 119 PRO C N   1 
ATOM   2575 C CA  . PRO C 2 120 ? 133.904 146.126 123.176 1.00 101.39 ? 119 PRO C CA  1 
ATOM   2576 C C   . PRO C 2 120 ? 133.895 146.767 121.800 1.00 101.39 ? 119 PRO C C   1 
ATOM   2577 O O   . PRO C 2 120 ? 133.056 147.638 121.553 1.00 101.39 ? 119 PRO C O   1 
ATOM   2578 C CB  . PRO C 2 120 ? 134.264 147.152 124.256 1.00 101.39 ? 119 PRO C CB  1 
ATOM   2579 C CG  . PRO C 2 120 ? 135.688 146.921 124.537 1.00 101.39 ? 119 PRO C CG  1 
ATOM   2580 C CD  . PRO C 2 120 ? 135.885 145.446 124.402 1.00 101.39 ? 119 PRO C CD  1 
ATOM   2581 N N   . LEU C 2 121 ? 134.798 146.382 120.901 1.00 100.65 ? 120 LEU C N   1 
ATOM   2582 C CA  . LEU C 2 121 ? 134.714 146.829 119.521 1.00 100.65 ? 120 LEU C CA  1 
ATOM   2583 C C   . LEU C 2 121 ? 133.689 146.012 118.746 1.00 100.65 ? 120 LEU C C   1 
ATOM   2584 O O   . LEU C 2 121 ? 132.744 146.568 118.180 1.00 100.65 ? 120 LEU C O   1 
ATOM   2585 C CB  . LEU C 2 121 ? 136.099 146.748 118.874 1.00 100.65 ? 120 LEU C CB  1 
ATOM   2586 C CG  . LEU C 2 121 ? 136.406 147.341 117.495 1.00 100.65 ? 120 LEU C CG  1 
ATOM   2587 C CD1 . LEU C 2 121 ? 136.120 146.390 116.344 1.00 100.65 ? 120 LEU C CD1 1 
ATOM   2588 C CD2 . LEU C 2 121 ? 135.634 148.636 117.309 1.00 100.65 ? 120 LEU C CD2 1 
ATOM   2589 N N   . LEU C 2 122 ? 133.855 144.690 118.713 1.00 98.77  ? 121 LEU C N   1 
ATOM   2590 C CA  . LEU C 2 122 ? 133.027 143.869 117.841 1.00 98.77  ? 121 LEU C CA  1 
ATOM   2591 C C   . LEU C 2 122 ? 131.615 143.657 118.354 1.00 98.77  ? 121 LEU C C   1 
ATOM   2592 O O   . LEU C 2 122 ? 130.729 143.363 117.547 1.00 98.77  ? 121 LEU C O   1 
ATOM   2593 C CB  . LEU C 2 122 ? 133.666 142.509 117.608 1.00 98.77  ? 121 LEU C CB  1 
ATOM   2594 C CG  . LEU C 2 122 ? 134.905 142.535 116.738 1.00 98.77  ? 121 LEU C CG  1 
ATOM   2595 C CD1 . LEU C 2 122 ? 135.403 141.136 116.618 1.00 98.77  ? 121 LEU C CD1 1 
ATOM   2596 C CD2 . LEU C 2 122 ? 134.572 143.081 115.381 1.00 98.77  ? 121 LEU C CD2 1 
ATOM   2597 N N   . ILE C 2 123 ? 131.372 143.801 119.659 1.00 102.47 ? 122 ILE C N   1 
ATOM   2598 C CA  . ILE C 2 123 ? 130.003 143.691 120.149 1.00 102.47 ? 122 ILE C CA  1 
ATOM   2599 C C   . ILE C 2 123 ? 129.177 144.884 119.703 1.00 102.47 ? 122 ILE C C   1 
ATOM   2600 O O   . ILE C 2 123 ? 127.947 144.807 119.672 1.00 102.47 ? 122 ILE C O   1 
ATOM   2601 C CB  . ILE C 2 123 ? 129.982 143.515 121.680 1.00 102.47 ? 122 ILE C CB  1 
ATOM   2602 C CG1 . ILE C 2 123 ? 130.599 144.709 122.413 1.00 102.47 ? 122 ILE C CG1 1 
ATOM   2603 C CG2 . ILE C 2 123 ? 130.748 142.283 122.068 1.00 102.47 ? 122 ILE C CG2 1 
ATOM   2604 C CD1 . ILE C 2 123 ? 129.616 145.722 122.994 1.00 102.47 ? 122 ILE C CD1 1 
ATOM   2605 N N   . ASP C 2 124 ? 129.825 145.994 119.367 1.00 106.16 ? 123 ASP C N   1 
ATOM   2606 C CA  . ASP C 2 124 ? 129.156 147.110 118.726 1.00 106.16 ? 123 ASP C CA  1 
ATOM   2607 C C   . ASP C 2 124 ? 129.174 146.995 117.210 1.00 106.16 ? 123 ASP C C   1 
ATOM   2608 O O   . ASP C 2 124 ? 128.299 147.561 116.544 1.00 106.16 ? 123 ASP C O   1 
ATOM   2609 C CB  . ASP C 2 124 ? 129.811 148.421 119.169 1.00 106.16 ? 123 ASP C CB  1 
ATOM   2610 C CG  . ASP C 2 124 ? 129.068 149.642 118.680 1.00 106.16 ? 123 ASP C CG  1 
ATOM   2611 O OD1 . ASP C 2 124 ? 127.961 149.908 119.190 1.00 106.16 ? 123 ASP C OD1 1 
ATOM   2612 O OD2 . ASP C 2 124 ? 129.596 150.342 117.793 1.00 106.16 ? 123 ASP C OD2 1 
ATOM   2613 N N   . ALA C 2 125 ? 130.125 146.255 116.653 1.00 102.83 ? 124 ALA C N   1 
ATOM   2614 C CA  . ALA C 2 125 ? 130.231 146.127 115.210 1.00 102.83 ? 124 ALA C CA  1 
ATOM   2615 C C   . ALA C 2 125 ? 129.412 144.979 114.646 1.00 102.83 ? 124 ALA C C   1 
ATOM   2616 O O   . ALA C 2 125 ? 129.309 144.863 113.423 1.00 102.83 ? 124 ALA C O   1 
ATOM   2617 C CB  . ALA C 2 125 ? 131.694 145.953 114.797 1.00 102.83 ? 124 ALA C CB  1 
ATOM   2618 N N   . ILE C 2 126 ? 128.844 144.127 115.488 1.00 99.10  ? 125 ILE C N   1 
ATOM   2619 C CA  . ILE C 2 126 ? 127.999 143.029 115.042 1.00 99.10  ? 125 ILE C CA  1 
ATOM   2620 C C   . ILE C 2 126 ? 126.563 143.208 115.511 1.00 99.10  ? 125 ILE C C   1 
ATOM   2621 O O   . ILE C 2 126 ? 125.626 143.122 114.718 1.00 99.10  ? 125 ILE C O   1 
ATOM   2622 C CB  . ILE C 2 126 ? 128.569 141.668 115.496 1.00 99.10  ? 125 ILE C CB  1 
ATOM   2623 C CG1 . ILE C 2 126 ? 129.869 141.369 114.761 1.00 99.10  ? 125 ILE C CG1 1 
ATOM   2624 C CG2 . ILE C 2 126 ? 127.576 140.558 115.250 1.00 99.10  ? 125 ILE C CG2 1 
ATOM   2625 C CD1 . ILE C 2 126 ? 130.578 140.149 115.266 1.00 99.10  ? 125 ILE C CD1 1 
ATOM   2626 N N   . ASP C 2 127 ? 126.373 143.494 116.794 1.00 106.48 ? 126 ASP C N   1 
ATOM   2627 C CA  . ASP C 2 127 ? 125.028 143.545 117.344 1.00 106.48 ? 126 ASP C CA  1 
ATOM   2628 C C   . ASP C 2 127 ? 124.273 144.805 116.954 1.00 106.48 ? 126 ASP C C   1 
ATOM   2629 O O   . ASP C 2 127 ? 123.052 144.849 117.113 1.00 106.48 ? 126 ASP C O   1 
ATOM   2630 C CB  . ASP C 2 127 ? 125.093 143.428 118.860 1.00 106.48 ? 126 ASP C CB  1 
ATOM   2631 C CG  . ASP C 2 127 ? 125.707 142.125 119.299 1.00 106.48 ? 126 ASP C CG  1 
ATOM   2632 O OD1 . ASP C 2 127 ? 125.607 141.157 118.524 1.00 106.48 ? 126 ASP C OD1 1 
ATOM   2633 O OD2 . ASP C 2 127 ? 126.298 142.070 120.396 1.00 106.48 ? 126 ASP C OD2 1 
ATOM   2634 N N   . GLN C 2 128 ? 124.965 145.826 116.465 1.00 103.70 ? 127 GLN C N   1 
ATOM   2635 C CA  . GLN C 2 128 ? 124.319 147.029 115.968 1.00 103.70 ? 127 GLN C CA  1 
ATOM   2636 C C   . GLN C 2 128 ? 124.845 147.437 114.603 1.00 103.70 ? 127 GLN C C   1 
ATOM   2637 O O   . GLN C 2 128 ? 124.343 148.412 114.033 1.00 103.70 ? 127 GLN C O   1 
ATOM   2638 C CB  . GLN C 2 128 ? 124.497 148.194 116.953 1.00 103.70 ? 127 GLN C CB  1 
ATOM   2639 C CG  . GLN C 2 128 ? 123.717 148.058 118.253 1.00 103.70 ? 127 GLN C CG  1 
ATOM   2640 C CD  . GLN C 2 128 ? 124.421 147.188 119.268 1.00 103.70 ? 127 GLN C CD  1 
ATOM   2641 O OE1 . GLN C 2 128 ? 125.611 146.913 119.140 1.00 103.70 ? 127 GLN C OE1 1 
ATOM   2642 N NE2 . GLN C 2 128 ? 123.686 146.738 120.275 1.00 103.70 ? 127 GLN C NE2 1 
ATOM   2643 N N   . LEU C 2 129 ? 125.847 146.721 114.087 1.00 94.70  ? 128 LEU C N   1 
ATOM   2644 C CA  . LEU C 2 129 ? 126.435 146.918 112.760 1.00 94.70  ? 128 LEU C CA  1 
ATOM   2645 C C   . LEU C 2 129 ? 126.994 148.324 112.583 1.00 94.70  ? 128 LEU C C   1 
ATOM   2646 O O   . LEU C 2 129 ? 126.907 148.912 111.506 1.00 94.70  ? 128 LEU C O   1 
ATOM   2647 C CB  . LEU C 2 129 ? 125.452 146.596 111.638 1.00 94.70  ? 128 LEU C CB  1 
ATOM   2648 C CG  . LEU C 2 129 ? 125.153 145.119 111.422 1.00 94.70  ? 128 LEU C CG  1 
ATOM   2649 C CD1 . LEU C 2 129 ? 123.976 144.654 112.255 1.00 94.70  ? 128 LEU C CD1 1 
ATOM   2650 C CD2 . LEU C 2 129 ? 124.966 144.836 109.971 1.00 94.70  ? 128 LEU C CD2 1 
ATOM   2651 N N   . ASN C 2 130 ? 127.562 148.858 113.626 1.00 100.99 ? 129 ASN C N   1 
ATOM   2652 C CA  . ASN C 2 130 ? 128.158 150.169 113.465 1.00 100.99 ? 129 ASN C CA  1 
ATOM   2653 C C   . ASN C 2 130 ? 129.522 150.042 112.798 1.00 100.99 ? 129 ASN C C   1 
ATOM   2654 O O   . ASN C 2 130 ? 130.288 149.133 113.120 1.00 100.99 ? 129 ASN C O   1 
ATOM   2655 C CB  . ASN C 2 130 ? 128.305 150.854 114.812 1.00 100.99 ? 129 ASN C CB  1 
ATOM   2656 C CG  . ASN C 2 130 ? 126.976 151.244 115.411 1.00 100.99 ? 129 ASN C CG  1 
ATOM   2657 O OD1 . ASN C 2 130 ? 126.109 151.793 114.729 1.00 100.99 ? 129 ASN C OD1 1 
ATOM   2658 N ND2 . ASN C 2 130 ? 126.795 150.940 116.688 1.00 100.99 ? 129 ASN C ND2 1 
ATOM   2659 N N   . PRO C 2 131 ? 129.844 150.924 111.869 1.00 101.65 ? 130 PRO C N   1 
ATOM   2660 C CA  . PRO C 2 131 ? 131.210 150.973 111.337 1.00 101.65 ? 130 PRO C CA  1 
ATOM   2661 C C   . PRO C 2 131 ? 132.184 151.597 112.323 1.00 101.65 ? 130 PRO C C   1 
ATOM   2662 O O   . PRO C 2 131 ? 131.825 151.901 113.464 1.00 101.65 ? 130 PRO C O   1 
ATOM   2663 C CB  . PRO C 2 131 ? 131.066 151.842 110.083 1.00 101.65 ? 130 PRO C CB  1 
ATOM   2664 C CG  . PRO C 2 131 ? 129.614 151.820 109.754 1.00 101.65 ? 130 PRO C CG  1 
ATOM   2665 C CD  . PRO C 2 131 ? 128.912 151.728 111.064 1.00 101.65 ? 130 PRO C CD  1 
ATOM   2666 N N   . ALA C 2 132 ? 133.421 151.803 111.902 1.00 100.64 ? 131 ALA C N   1 
ATOM   2667 C CA  . ALA C 2 132 ? 134.364 152.498 112.760 1.00 100.64 ? 131 ALA C CA  1 
ATOM   2668 C C   . ALA C 2 132 ? 134.746 153.847 112.164 1.00 100.64 ? 131 ALA C C   1 
ATOM   2669 O O   . ALA C 2 132 ? 134.383 154.895 112.698 1.00 100.64 ? 131 ALA C O   1 
ATOM   2670 C CB  . ALA C 2 132 ? 135.585 151.654 112.988 1.00 100.64 ? 131 ALA C CB  1 
ATOM   2671 N N   . VAL D 3 7   ? 119.932 143.789 144.278 1.00 148.19 ? 7   VAL L N   1 
ATOM   2672 C CA  . VAL D 3 7   ? 119.422 144.345 145.522 1.00 148.19 ? 7   VAL L CA  1 
ATOM   2673 C C   . VAL D 3 7   ? 118.172 143.585 145.932 1.00 148.19 ? 7   VAL L C   1 
ATOM   2674 O O   . VAL D 3 7   ? 117.097 143.815 145.390 1.00 148.19 ? 7   VAL L O   1 
ATOM   2675 C CB  . VAL D 3 7   ? 119.128 145.847 145.387 1.00 148.19 ? 7   VAL L CB  1 
ATOM   2676 C CG1 . VAL D 3 7   ? 118.612 146.412 146.700 1.00 148.19 ? 7   VAL L CG1 1 
ATOM   2677 C CG2 . VAL D 3 7   ? 120.365 146.591 144.933 1.00 148.19 ? 7   VAL L CG2 1 
ATOM   2678 N N   . THR D 3 8   ? 118.316 142.668 146.881 1.00 151.08 ? 8   THR L N   1 
ATOM   2679 C CA  . THR D 3 8   ? 117.207 141.858 147.359 1.00 151.08 ? 8   THR L CA  1 
ATOM   2680 C C   . THR D 3 8   ? 116.975 142.120 148.840 1.00 151.08 ? 8   THR L C   1 
ATOM   2681 O O   . THR D 3 8   ? 117.796 142.737 149.523 1.00 151.08 ? 8   THR L O   1 
ATOM   2682 C CB  . THR D 3 8   ? 117.467 140.366 147.129 1.00 151.08 ? 8   THR L CB  1 
ATOM   2683 O OG1 . THR D 3 8   ? 118.637 139.970 147.853 1.00 151.08 ? 8   THR L OG1 1 
ATOM   2684 C CG2 . THR D 3 8   ? 117.667 140.082 145.653 1.00 151.08 ? 8   THR L CG2 1 
ATOM   2685 N N   . GLN D 3 9   ? 115.843 141.625 149.336 1.00 156.88 ? 9   GLN L N   1 
ATOM   2686 C CA  . GLN D 3 9   ? 115.460 141.857 150.721 1.00 156.88 ? 9   GLN L CA  1 
ATOM   2687 C C   . GLN D 3 9   ? 114.453 140.804 151.152 1.00 156.88 ? 9   GLN L C   1 
ATOM   2688 O O   . GLN D 3 9   ? 113.502 140.517 150.421 1.00 156.88 ? 9   GLN L O   1 
ATOM   2689 C CB  . GLN D 3 9   ? 114.867 143.256 150.894 1.00 156.88 ? 9   GLN L CB  1 
ATOM   2690 C CG  . GLN D 3 9   ? 114.552 143.600 152.327 1.00 156.88 ? 9   GLN L CG  1 
ATOM   2691 C CD  . GLN D 3 9   ? 115.784 143.557 153.200 1.00 156.88 ? 9   GLN L CD  1 
ATOM   2692 O OE1 . GLN D 3 9   ? 115.984 142.615 153.964 1.00 156.88 ? 9   GLN L OE1 1 
ATOM   2693 N NE2 . GLN D 3 9   ? 116.624 144.578 153.088 1.00 156.88 ? 9   GLN L NE2 1 
ATOM   2694 N N   . SER D 3 10  ? 114.662 140.241 152.337 1.00 155.63 ? 10  SER L N   1 
ATOM   2695 C CA  . SER D 3 10  ? 113.757 139.306 152.978 1.00 155.63 ? 10  SER L CA  1 
ATOM   2696 C C   . SER D 3 10  ? 113.325 139.864 154.333 1.00 155.63 ? 10  SER L C   1 
ATOM   2697 O O   . SER D 3 10  ? 114.060 140.656 154.930 1.00 155.63 ? 10  SER L O   1 
ATOM   2698 C CB  . SER D 3 10  ? 114.438 137.940 153.151 1.00 155.63 ? 10  SER L CB  1 
ATOM   2699 O OG  . SER D 3 10  ? 115.553 138.024 154.019 1.00 155.63 ? 10  SER L OG  1 
ATOM   2700 N N   . PRO D 3 11  ? 112.131 139.491 154.853 1.00 154.14 ? 11  PRO L N   1 
ATOM   2701 C CA  . PRO D 3 11  ? 111.707 140.038 156.150 1.00 154.14 ? 11  PRO L CA  1 
ATOM   2702 C C   . PRO D 3 11  ? 112.458 139.440 157.328 1.00 154.14 ? 11  PRO L C   1 
ATOM   2703 O O   . PRO D 3 11  ? 113.363 138.619 157.154 1.00 154.14 ? 11  PRO L O   1 
ATOM   2704 C CB  . PRO D 3 11  ? 110.215 139.692 156.207 1.00 154.14 ? 11  PRO L CB  1 
ATOM   2705 C CG  . PRO D 3 11  ? 110.087 138.493 155.372 1.00 154.14 ? 11  PRO L CG  1 
ATOM   2706 C CD  . PRO D 3 11  ? 111.074 138.657 154.254 1.00 154.14 ? 11  PRO L CD  1 
ATOM   2707 N N   . ALA D 3 12  ? 112.075 139.841 158.537 1.00 160.69 ? 12  ALA L N   1 
ATOM   2708 C CA  . ALA D 3 12  ? 112.833 139.495 159.728 1.00 160.69 ? 12  ALA L CA  1 
ATOM   2709 C C   . ALA D 3 12  ? 112.621 138.030 160.108 1.00 160.69 ? 12  ALA L C   1 
ATOM   2710 O O   . ALA D 3 12  ? 111.774 137.324 159.554 1.00 160.69 ? 12  ALA L O   1 
ATOM   2711 C CB  . ALA D 3 12  ? 112.440 140.403 160.891 1.00 160.69 ? 12  ALA L CB  1 
ATOM   2712 N N   . SER D 3 13  ? 113.413 137.580 161.078 1.00 165.60 ? 13  SER L N   1 
ATOM   2713 C CA  . SER D 3 13  ? 113.387 136.190 161.505 1.00 165.60 ? 13  SER L CA  1 
ATOM   2714 C C   . SER D 3 13  ? 112.162 135.911 162.363 1.00 165.60 ? 13  SER L C   1 
ATOM   2715 O O   . SER D 3 13  ? 111.799 136.709 163.231 1.00 165.60 ? 13  SER L O   1 
ATOM   2716 C CB  . SER D 3 13  ? 114.656 135.857 162.285 1.00 165.60 ? 13  SER L CB  1 
ATOM   2717 O OG  . SER D 3 13  ? 115.801 136.017 161.468 1.00 165.60 ? 13  SER L OG  1 
ATOM   2718 N N   . LEU D 3 14  ? 111.532 134.766 162.121 1.00 167.47 ? 14  LEU L N   1 
ATOM   2719 C CA  . LEU D 3 14  ? 110.325 134.379 162.844 1.00 167.47 ? 14  LEU L CA  1 
ATOM   2720 C C   . LEU D 3 14  ? 110.126 132.869 162.809 1.00 167.47 ? 14  LEU L C   1 
ATOM   2721 O O   . LEU D 3 14  ? 110.768 132.168 162.029 1.00 167.47 ? 14  LEU L O   1 
ATOM   2722 C CB  . LEU D 3 14  ? 109.088 135.078 162.266 1.00 167.47 ? 14  LEU L CB  1 
ATOM   2723 C CG  . LEU D 3 14  ? 108.475 134.609 160.942 1.00 167.47 ? 14  LEU L CG  1 
ATOM   2724 C CD1 . LEU D 3 14  ? 107.052 135.102 160.850 1.00 167.47 ? 14  LEU L CD1 1 
ATOM   2725 C CD2 . LEU D 3 14  ? 109.247 135.104 159.735 1.00 167.47 ? 14  LEU L CD2 1 
HETATM 2726 N N   . SEP D 3 15  ? 109.233 132.373 163.659 1.00 174.36 ? 15  SEP L N   1 
HETATM 2727 C CA  . SEP D 3 15  ? 108.949 130.945 163.717 1.00 174.36 ? 15  SEP L CA  1 
HETATM 2728 C CB  . SEP D 3 15  ? 109.812 130.268 164.780 1.00 174.36 ? 15  SEP L CB  1 
HETATM 2729 O OG  . SEP D 3 15  ? 109.493 128.892 164.881 1.00 174.36 ? 15  SEP L OG  1 
HETATM 2730 C C   . SEP D 3 15  ? 107.478 130.681 164.001 1.00 174.36 ? 15  SEP L C   1 
HETATM 2731 O O   . SEP D 3 15  ? 106.926 129.677 163.546 1.00 174.36 ? 15  SEP L O   1 
HETATM 2732 P P   . SEP D 3 15  ? 110.564 128.140 165.814 1.00 174.36 ? 15  SEP L P   1 
HETATM 2733 O O1P . SEP D 3 15  ? 112.048 128.427 165.266 1.00 174.36 ? 15  SEP L O1P 1 
HETATM 2734 O O2P . SEP D 3 15  ? 110.275 126.557 165.783 1.00 174.36 ? 15  SEP L O2P 1 
HETATM 2735 O O3P . SEP D 3 15  ? 110.434 128.694 167.319 1.00 174.36 ? 15  SEP L O3P 1 
ATOM   2736 N N   . VAL D 3 16  ? 106.877 131.593 164.766 1.00 172.31 ? 16  VAL L N   1 
ATOM   2737 C CA  . VAL D 3 16  ? 105.461 131.592 165.148 1.00 172.31 ? 16  VAL L CA  1 
ATOM   2738 C C   . VAL D 3 16  ? 105.044 130.310 165.874 1.00 172.31 ? 16  VAL L C   1 
ATOM   2739 O O   . VAL D 3 16  ? 104.905 130.305 167.097 1.00 172.31 ? 16  VAL L O   1 
ATOM   2740 C CB  . VAL D 3 16  ? 104.550 131.847 163.921 1.00 172.31 ? 16  VAL L CB  1 
ATOM   2741 C CG1 . VAL D 3 16  ? 103.081 131.916 164.331 1.00 172.31 ? 16  VAL L CG1 1 
ATOM   2742 C CG2 . VAL D 3 16  ? 104.964 133.117 163.221 1.00 172.31 ? 16  VAL L CG2 1 
ATOM   2743 N N   . ALA D 3 17  ? 104.856 129.225 165.128 1.00 172.87 ? 17  ALA L N   1 
ATOM   2744 C CA  . ALA D 3 17  ? 104.280 128.010 165.683 1.00 172.87 ? 17  ALA L CA  1 
ATOM   2745 C C   . ALA D 3 17  ? 104.830 126.815 164.918 1.00 172.87 ? 17  ALA L C   1 
ATOM   2746 O O   . ALA D 3 17  ? 105.707 126.952 164.061 1.00 172.87 ? 17  ALA L O   1 
ATOM   2747 C CB  . ALA D 3 17  ? 102.749 128.066 165.629 1.00 172.87 ? 17  ALA L CB  1 
ATOM   2748 N N   . THR D 3 18  ? 104.309 125.630 165.240 1.00 174.14 ? 18  THR L N   1 
ATOM   2749 C CA  . THR D 3 18  ? 104.692 124.391 164.575 1.00 174.14 ? 18  THR L CA  1 
ATOM   2750 C C   . THR D 3 18  ? 103.516 123.756 163.843 1.00 174.14 ? 18  THR L C   1 
ATOM   2751 O O   . THR D 3 18  ? 103.510 122.541 163.623 1.00 174.14 ? 18  THR L O   1 
ATOM   2752 C CB  . THR D 3 18  ? 105.272 123.396 165.580 1.00 174.14 ? 18  THR L CB  1 
ATOM   2753 O OG1 . THR D 3 18  ? 104.256 123.023 166.517 1.00 174.14 ? 18  THR L OG1 1 
ATOM   2754 C CG2 . THR D 3 18  ? 106.439 124.014 166.333 1.00 174.14 ? 18  THR L CG2 1 
ATOM   2755 N N   . GLY D 3 19  ? 102.513 124.547 163.475 1.00 173.58 ? 19  GLY L N   1 
ATOM   2756 C CA  . GLY D 3 19  ? 101.346 124.003 162.813 1.00 173.58 ? 19  GLY L CA  1 
ATOM   2757 C C   . GLY D 3 19  ? 100.761 124.898 161.742 1.00 173.58 ? 19  GLY L C   1 
ATOM   2758 O O   . GLY D 3 19  ? 99.650  124.651 161.265 1.00 173.58 ? 19  GLY L O   1 
ATOM   2759 N N   . GLU D 3 20  ? 101.496 125.932 161.345 1.00 175.18 ? 20  GLU L N   1 
ATOM   2760 C CA  . GLU D 3 20  ? 100.976 126.969 160.466 1.00 175.18 ? 20  GLU L CA  1 
ATOM   2761 C C   . GLU D 3 20  ? 101.936 127.212 159.308 1.00 175.18 ? 20  GLU L C   1 
ATOM   2762 O O   . GLU D 3 20  ? 103.023 126.632 159.231 1.00 175.18 ? 20  GLU L O   1 
ATOM   2763 C CB  . GLU D 3 20  ? 100.748 128.275 161.233 1.00 175.18 ? 20  GLU L CB  1 
ATOM   2764 C CG  . GLU D 3 20  ? 99.663  128.214 162.281 1.00 175.18 ? 20  GLU L CG  1 
ATOM   2765 C CD  . GLU D 3 20  ? 99.541  129.512 163.042 1.00 175.18 ? 20  GLU L CD  1 
ATOM   2766 O OE1 . GLU D 3 20  ? 100.396 130.398 162.836 1.00 175.18 ? 20  GLU L OE1 1 
ATOM   2767 O OE2 . GLU D 3 20  ? 98.595  129.651 163.844 1.00 175.18 ? 20  GLU L OE2 1 
ATOM   2768 N N   . LYS D 3 21  ? 101.519 128.100 158.411 1.00 164.82 ? 21  LYS L N   1 
ATOM   2769 C CA  . LYS D 3 21  ? 102.324 128.562 157.296 1.00 164.82 ? 21  LYS L CA  1 
ATOM   2770 C C   . LYS D 3 21  ? 103.205 129.726 157.743 1.00 164.82 ? 21  LYS L C   1 
ATOM   2771 O O   . LYS D 3 21  ? 103.130 130.191 158.882 1.00 164.82 ? 21  LYS L O   1 
ATOM   2772 C CB  . LYS D 3 21  ? 101.417 128.977 156.142 1.00 164.82 ? 21  LYS L CB  1 
ATOM   2773 C CG  . LYS D 3 21  ? 100.549 130.174 156.488 1.00 164.82 ? 21  LYS L CG  1 
ATOM   2774 C CD  . LYS D 3 21  ? 99.550  130.501 155.393 1.00 164.82 ? 21  LYS L CD  1 
ATOM   2775 C CE  . LYS D 3 21  ? 100.226 131.084 154.171 1.00 164.82 ? 21  LYS L CE  1 
ATOM   2776 N NZ  . LYS D 3 21  ? 100.856 132.398 154.459 1.00 164.82 ? 21  LYS L NZ  1 
ATOM   2777 N N   . VAL D 3 22  ? 104.049 130.210 156.835 1.00 157.00 ? 22  VAL L N   1 
ATOM   2778 C CA  . VAL D 3 22  ? 104.854 131.404 157.083 1.00 157.00 ? 22  VAL L CA  1 
ATOM   2779 C C   . VAL D 3 22  ? 105.125 132.091 155.749 1.00 157.00 ? 22  VAL L C   1 
ATOM   2780 O O   . VAL D 3 22  ? 105.404 131.437 154.741 1.00 157.00 ? 22  VAL L O   1 
ATOM   2781 C CB  . VAL D 3 22  ? 106.154 131.076 157.859 1.00 157.00 ? 22  VAL L CB  1 
ATOM   2782 C CG1 . VAL D 3 22  ? 107.029 130.068 157.126 1.00 157.00 ? 22  VAL L CG1 1 
ATOM   2783 C CG2 . VAL D 3 22  ? 106.940 132.342 158.180 1.00 157.00 ? 22  VAL L CG2 1 
ATOM   2784 N N   . THR D 3 23  ? 104.981 133.409 155.731 1.00 160.73 ? 23  THR L N   1 
ATOM   2785 C CA  . THR D 3 23  ? 105.205 134.201 154.533 1.00 160.73 ? 23  THR L CA  1 
ATOM   2786 C C   . THR D 3 23  ? 106.617 134.769 154.545 1.00 160.73 ? 23  THR L C   1 
ATOM   2787 O O   . THR D 3 23  ? 107.012 135.441 155.502 1.00 160.73 ? 23  THR L O   1 
ATOM   2788 C CB  . THR D 3 23  ? 104.176 135.330 154.454 1.00 160.73 ? 23  THR L CB  1 
ATOM   2789 O OG1 . THR D 3 23  ? 102.868 134.772 154.285 1.00 160.73 ? 23  THR L OG1 1 
ATOM   2790 C CG2 . THR D 3 23  ? 104.483 136.279 153.311 1.00 160.73 ? 23  THR L CG2 1 
ATOM   2791 N N   . ILE D 3 24  ? 107.378 134.491 153.490 1.00 155.26 ? 24  ILE L N   1 
ATOM   2792 C CA  . ILE D 3 24  ? 108.685 135.101 153.280 1.00 155.26 ? 24  ILE L CA  1 
ATOM   2793 C C   . ILE D 3 24  ? 108.620 135.901 151.989 1.00 155.26 ? 24  ILE L C   1 
ATOM   2794 O O   . ILE D 3 24  ? 108.269 135.359 150.937 1.00 155.26 ? 24  ILE L O   1 
ATOM   2795 C CB  . ILE D 3 24  ? 109.806 134.051 153.221 1.00 155.26 ? 24  ILE L CB  1 
ATOM   2796 C CG1 . ILE D 3 24  ? 109.805 133.200 154.489 1.00 155.26 ? 24  ILE L CG1 1 
ATOM   2797 C CG2 . ILE D 3 24  ? 111.141 134.733 153.075 1.00 155.26 ? 24  ILE L CG2 1 
ATOM   2798 C CD1 . ILE D 3 24  ? 110.046 133.987 155.752 1.00 155.26 ? 24  ILE L CD1 1 
ATOM   2799 N N   . ARG D 3 25  ? 108.950 137.185 152.066 1.00 152.66 ? 25  ARG L N   1 
ATOM   2800 C CA  . ARG D 3 25  ? 108.798 138.098 150.940 1.00 152.66 ? 25  ARG L CA  1 
ATOM   2801 C C   . ARG D 3 25  ? 110.169 138.489 150.411 1.00 152.66 ? 25  ARG L C   1 
ATOM   2802 O O   . ARG D 3 25  ? 110.893 139.258 151.050 1.00 152.66 ? 25  ARG L O   1 
ATOM   2803 C CB  . ARG D 3 25  ? 108.005 139.336 151.346 1.00 152.66 ? 25  ARG L CB  1 
ATOM   2804 C CG  . ARG D 3 25  ? 106.553 139.064 151.677 1.00 152.66 ? 25  ARG L CG  1 
ATOM   2805 C CD  . ARG D 3 25  ? 105.840 140.343 152.071 1.00 152.66 ? 25  ARG L CD  1 
ATOM   2806 N NE  . ARG D 3 25  ? 105.741 141.281 150.957 1.00 152.66 ? 25  ARG L NE  1 
ATOM   2807 C CZ  . ARG D 3 25  ? 106.414 142.424 150.882 1.00 152.66 ? 25  ARG L CZ  1 
ATOM   2808 N NH1 . ARG D 3 25  ? 107.243 142.768 151.856 1.00 152.66 ? 25  ARG L NH1 1 
ATOM   2809 N NH2 . ARG D 3 25  ? 106.265 143.218 149.834 1.00 152.66 ? 25  ARG L NH2 1 
ATOM   2810 N N   . CYS D 3 26  ? 110.516 137.980 149.236 1.00 157.99 ? 26  CYS L N   1 
ATOM   2811 C CA  . CYS D 3 26  ? 111.729 138.399 148.552 1.00 157.99 ? 26  CYS L CA  1 
ATOM   2812 C C   . CYS D 3 26  ? 111.331 139.528 147.609 1.00 157.99 ? 26  CYS L C   1 
ATOM   2813 O O   . CYS D 3 26  ? 110.560 139.320 146.662 1.00 157.99 ? 26  CYS L O   1 
ATOM   2814 C CB  . CYS D 3 26  ? 112.374 137.228 147.814 1.00 157.99 ? 26  CYS L CB  1 
ATOM   2815 S SG  . CYS D 3 26  ? 114.080 137.484 147.242 1.00 157.99 ? 26  CYS L SG  1 
ATOM   2816 N N   . ILE D 3 27  ? 111.817 140.730 147.895 1.00 157.09 ? 27  ILE L N   1 
ATOM   2817 C CA  . ILE D 3 27  ? 111.515 141.911 147.100 1.00 157.09 ? 27  ILE L CA  1 
ATOM   2818 C C   . ILE D 3 27  ? 112.820 142.455 146.531 1.00 157.09 ? 27  ILE L C   1 
ATOM   2819 O O   . ILE D 3 27  ? 113.854 142.470 147.208 1.00 157.09 ? 27  ILE L O   1 
ATOM   2820 C CB  . ILE D 3 27  ? 110.738 142.964 147.929 1.00 157.09 ? 27  ILE L CB  1 
ATOM   2821 C CG1 . ILE D 3 27  ? 110.292 144.138 147.058 1.00 157.09 ? 27  ILE L CG1 1 
ATOM   2822 C CG2 . ILE D 3 27  ? 111.508 143.421 149.169 1.00 157.09 ? 27  ILE L CG2 1 
ATOM   2823 C CD1 . ILE D 3 27  ? 109.243 145.005 147.704 1.00 157.09 ? 27  ILE L CD1 1 
ATOM   2824 N N   . THR D 3 28  ? 112.784 142.839 145.259 1.00 159.17 ? 28  THR L N   1 
ATOM   2825 C CA  . THR D 3 28  ? 113.976 143.238 144.528 1.00 159.17 ? 28  THR L CA  1 
ATOM   2826 C C   . THR D 3 28  ? 113.713 144.557 143.825 1.00 159.17 ? 28  THR L C   1 
ATOM   2827 O O   . THR D 3 28  ? 112.759 144.669 143.053 1.00 159.17 ? 28  THR L O   1 
ATOM   2828 C CB  . THR D 3 28  ? 114.379 142.167 143.515 1.00 159.17 ? 28  THR L CB  1 
ATOM   2829 O OG1 . THR D 3 28  ? 114.707 140.960 144.210 1.00 159.17 ? 28  THR L OG1 1 
ATOM   2830 C CG2 . THR D 3 28  ? 115.575 142.618 142.703 1.00 159.17 ? 28  THR L CG2 1 
ATOM   2831 N N   . SER D 3 29  ? 114.562 145.546 144.086 1.00 163.33 ? 29  SER L N   1 
ATOM   2832 C CA  . SER D 3 29  ? 114.348 146.899 143.595 1.00 163.33 ? 29  SER L CA  1 
ATOM   2833 C C   . SER D 3 29  ? 115.107 147.209 142.314 1.00 163.33 ? 29  SER L C   1 
ATOM   2834 O O   . SER D 3 29  ? 115.023 148.338 141.824 1.00 163.33 ? 29  SER L O   1 
ATOM   2835 C CB  . SER D 3 29  ? 114.741 147.915 144.671 1.00 163.33 ? 29  SER L CB  1 
ATOM   2836 O OG  . SER D 3 29  ? 116.137 147.882 144.903 1.00 163.33 ? 29  SER L OG  1 
ATOM   2837 N N   . THR D 3 30  ? 115.843 146.249 141.756 1.00 164.99 ? 30  THR L N   1 
ATOM   2838 C CA  . THR D 3 30  ? 116.644 146.564 140.579 1.00 164.99 ? 30  THR L CA  1 
ATOM   2839 C C   . THR D 3 30  ? 115.794 146.561 139.316 1.00 164.99 ? 30  THR L C   1 
ATOM   2840 O O   . THR D 3 30  ? 115.565 147.610 138.709 1.00 164.99 ? 30  THR L O   1 
ATOM   2841 C CB  . THR D 3 30  ? 117.799 145.570 140.434 1.00 164.99 ? 30  THR L CB  1 
ATOM   2842 O OG1 . THR D 3 30  ? 117.276 144.250 140.244 1.00 164.99 ? 30  THR L OG1 1 
ATOM   2843 C CG2 . THR D 3 30  ? 118.684 145.590 141.667 1.00 164.99 ? 30  THR L CG2 1 
ATOM   2844 N N   . ASP D 3 31  ? 115.279 145.396 138.938 1.00 164.26 ? 31  ASP L N   1 
ATOM   2845 C CA  . ASP D 3 31  ? 114.579 145.220 137.674 1.00 164.26 ? 31  ASP L CA  1 
ATOM   2846 C C   . ASP D 3 31  ? 113.394 144.300 137.916 1.00 164.26 ? 31  ASP L C   1 
ATOM   2847 O O   . ASP D 3 31  ? 113.030 144.013 139.059 1.00 164.26 ? 31  ASP L O   1 
ATOM   2848 C CB  . ASP D 3 31  ? 115.521 144.648 136.607 1.00 164.26 ? 31  ASP L CB  1 
ATOM   2849 C CG  . ASP D 3 31  ? 116.554 145.649 136.134 1.00 164.26 ? 31  ASP L CG  1 
ATOM   2850 O OD1 . ASP D 3 31  ? 116.234 146.851 136.051 1.00 164.26 ? 31  ASP L OD1 1 
ATOM   2851 O OD2 . ASP D 3 31  ? 117.699 145.233 135.857 1.00 164.26 ? 31  ASP L OD2 1 
ATOM   2852 N N   . ILE D 3 32  ? 112.794 143.824 136.831 1.00 160.83 ? 32  ILE L N   1 
ATOM   2853 C CA  . ILE D 3 32  ? 111.781 142.780 136.901 1.00 160.83 ? 32  ILE L CA  1 
ATOM   2854 C C   . ILE D 3 32  ? 112.419 141.457 136.507 1.00 160.83 ? 32  ILE L C   1 
ATOM   2855 O O   . ILE D 3 32  ? 113.251 141.391 135.593 1.00 160.83 ? 32  ILE L O   1 
ATOM   2856 C CB  . ILE D 3 32  ? 110.549 143.107 136.032 1.00 160.83 ? 32  ILE L CB  1 
ATOM   2857 C CG1 . ILE D 3 32  ? 110.920 143.326 134.565 1.00 160.83 ? 32  ILE L CG1 1 
ATOM   2858 C CG2 . ILE D 3 32  ? 109.826 144.321 136.583 1.00 160.83 ? 32  ILE L CG2 1 
ATOM   2859 C CD1 . ILE D 3 32  ? 109.722 143.386 133.647 1.00 160.83 ? 32  ILE L CD1 1 
ATOM   2860 N N   . ASP D 3 33  ? 112.053 140.403 137.226 1.00 159.72 ? 33  ASP L N   1 
ATOM   2861 C CA  . ASP D 3 33  ? 112.698 139.110 137.097 1.00 159.72 ? 33  ASP L CA  1 
ATOM   2862 C C   . ASP D 3 33  ? 111.634 138.032 137.007 1.00 159.72 ? 33  ASP L C   1 
ATOM   2863 O O   . ASP D 3 33  ? 110.621 138.088 137.709 1.00 159.72 ? 33  ASP L O   1 
ATOM   2864 C CB  . ASP D 3 33  ? 113.607 138.828 138.295 1.00 159.72 ? 33  ASP L CB  1 
ATOM   2865 C CG  . ASP D 3 33  ? 114.752 139.807 138.401 1.00 159.72 ? 33  ASP L CG  1 
ATOM   2866 O OD1 . ASP D 3 33  ? 115.219 140.296 137.357 1.00 159.72 ? 33  ASP L OD1 1 
ATOM   2867 O OD2 . ASP D 3 33  ? 115.181 140.097 139.535 1.00 159.72 ? 33  ASP L OD2 1 
ATOM   2868 N N   . ASP D 3 34  ? 111.866 137.055 136.139 1.00 160.02 ? 34  ASP L N   1 
ATOM   2869 C CA  . ASP D 3 34  ? 111.060 135.847 136.104 1.00 160.02 ? 34  ASP L CA  1 
ATOM   2870 C C   . ASP D 3 34  ? 111.730 134.701 136.839 1.00 160.02 ? 34  ASP L C   1 
ATOM   2871 O O   . ASP D 3 34  ? 111.160 133.610 136.922 1.00 160.02 ? 34  ASP L O   1 
ATOM   2872 C CB  . ASP D 3 34  ? 110.772 135.449 134.659 1.00 160.02 ? 34  ASP L CB  1 
ATOM   2873 C CG  . ASP D 3 34  ? 109.846 136.418 133.969 1.00 160.02 ? 34  ASP L CG  1 
ATOM   2874 O OD1 . ASP D 3 34  ? 109.014 137.027 134.668 1.00 160.02 ? 34  ASP L OD1 1 
ATOM   2875 O OD2 . ASP D 3 34  ? 109.951 136.577 132.735 1.00 160.02 ? 34  ASP L OD2 1 
ATOM   2876 N N   . ASP D 3 35  ? 112.918 134.935 137.390 1.00 159.02 ? 35  ASP L N   1 
ATOM   2877 C CA  . ASP D 3 35  ? 113.731 133.881 137.985 1.00 159.02 ? 35  ASP L CA  1 
ATOM   2878 C C   . ASP D 3 35  ? 114.230 134.378 139.333 1.00 159.02 ? 35  ASP L C   1 
ATOM   2879 O O   . ASP D 3 35  ? 114.842 135.446 139.416 1.00 159.02 ? 35  ASP L O   1 
ATOM   2880 C CB  . ASP D 3 35  ? 114.896 133.516 137.072 1.00 159.02 ? 35  ASP L CB  1 
ATOM   2881 C CG  . ASP D 3 35  ? 114.445 132.898 135.766 1.00 159.02 ? 35  ASP L CG  1 
ATOM   2882 O OD1 . ASP D 3 35  ? 113.409 132.202 135.758 1.00 159.02 ? 35  ASP L OD1 1 
ATOM   2883 O OD2 . ASP D 3 35  ? 115.119 133.124 134.738 1.00 159.02 ? 35  ASP L OD2 1 
ATOM   2884 N N   . MET D 3 36  ? 113.979 133.597 140.379 1.00 154.44 ? 36  MET L N   1 
ATOM   2885 C CA  . MET D 3 36  ? 114.275 134.011 141.746 1.00 154.44 ? 36  MET L CA  1 
ATOM   2886 C C   . MET D 3 36  ? 114.317 132.753 142.593 1.00 154.44 ? 36  MET L C   1 
ATOM   2887 O O   . MET D 3 36  ? 113.290 132.089 142.749 1.00 154.44 ? 36  MET L O   1 
ATOM   2888 C CB  . MET D 3 36  ? 113.203 134.972 142.241 1.00 154.44 ? 36  MET L CB  1 
ATOM   2889 C CG  . MET D 3 36  ? 113.493 135.638 143.556 1.00 154.44 ? 36  MET L CG  1 
ATOM   2890 S SD  . MET D 3 36  ? 114.890 136.766 143.488 1.00 154.44 ? 36  MET L SD  1 
ATOM   2891 C CE  . MET D 3 36  ? 114.241 138.109 142.507 1.00 154.44 ? 36  MET L CE  1 
ATOM   2892 N N   . ASN D 3 37  ? 115.481 132.419 143.138 1.00 145.42 ? 37  ASN L N   1 
ATOM   2893 C CA  . ASN D 3 37  ? 115.681 131.097 143.709 1.00 145.42 ? 37  ASN L CA  1 
ATOM   2894 C C   . ASN D 3 37  ? 115.810 131.138 145.229 1.00 145.42 ? 37  ASN L C   1 
ATOM   2895 O O   . ASN D 3 37  ? 116.154 132.166 145.830 1.00 145.42 ? 37  ASN L O   1 
ATOM   2896 C CB  . ASN D 3 37  ? 116.895 130.403 143.066 1.00 145.42 ? 37  ASN L CB  1 
ATOM   2897 C CG  . ASN D 3 37  ? 118.201 131.153 143.233 1.00 145.42 ? 37  ASN L CG  1 
ATOM   2898 O OD1 . ASN D 3 37  ? 118.302 132.115 143.958 1.00 145.42 ? 37  ASN L OD1 1 
ATOM   2899 N ND2 . ASN D 3 37  ? 119.220 130.691 142.540 1.00 145.42 ? 37  ASN L ND2 1 
ATOM   2900 N N   . TRP D 3 38  ? 115.585 129.966 145.825 1.00 143.57 ? 38  TRP L N   1 
ATOM   2901 C CA  . TRP D 3 38  ? 115.548 129.786 147.266 1.00 143.57 ? 38  TRP L CA  1 
ATOM   2902 C C   . TRP D 3 38  ? 116.414 128.607 147.684 1.00 143.57 ? 38  TRP L C   1 
ATOM   2903 O O   . TRP D 3 38  ? 116.304 127.504 147.129 1.00 143.57 ? 38  TRP L O   1 
ATOM   2904 C CB  . TRP D 3 38  ? 114.134 129.547 147.733 1.00 143.57 ? 38  TRP L CB  1 
ATOM   2905 C CG  . TRP D 3 38  ? 113.229 130.688 147.530 1.00 143.57 ? 38  TRP L CG  1 
ATOM   2906 C CD1 . TRP D 3 38  ? 112.390 130.891 146.480 1.00 143.57 ? 38  TRP L CD1 1 
ATOM   2907 C CD2 . TRP D 3 38  ? 113.038 131.783 148.417 1.00 143.57 ? 38  TRP L CD2 1 
ATOM   2908 N NE1 . TRP D 3 38  ? 111.693 132.058 146.652 1.00 143.57 ? 38  TRP L NE1 1 
ATOM   2909 C CE2 . TRP D 3 38  ? 112.074 132.625 147.838 1.00 143.57 ? 38  TRP L CE2 1 
ATOM   2910 C CE3 . TRP D 3 38  ? 113.594 132.139 149.646 1.00 143.57 ? 38  TRP L CE3 1 
ATOM   2911 C CZ2 . TRP D 3 38  ? 111.654 133.795 148.444 1.00 143.57 ? 38  TRP L CZ2 1 
ATOM   2912 C CZ3 . TRP D 3 38  ? 113.176 133.299 150.247 1.00 143.57 ? 38  TRP L CZ3 1 
ATOM   2913 C CH2 . TRP D 3 38  ? 112.218 134.118 149.646 1.00 143.57 ? 38  TRP L CH2 1 
ATOM   2914 N N   . TYR D 3 39  ? 117.271 128.854 148.671 1.00 136.08 ? 39  TYR L N   1 
ATOM   2915 C CA  . TYR D 3 39  ? 118.114 127.833 149.275 1.00 136.08 ? 39  TYR L CA  1 
ATOM   2916 C C   . TYR D 3 39  ? 117.754 127.729 150.748 1.00 136.08 ? 39  TYR L C   1 
ATOM   2917 O O   . TYR D 3 39  ? 117.178 128.651 151.327 1.00 136.08 ? 39  TYR L O   1 
ATOM   2918 C CB  . TYR D 3 39  ? 119.614 128.153 149.171 1.00 136.08 ? 39  TYR L CB  1 
ATOM   2919 C CG  . TYR D 3 39  ? 120.228 128.204 147.789 1.00 136.08 ? 39  TYR L CG  1 
ATOM   2920 C CD1 . TYR D 3 39  ? 119.535 127.806 146.663 1.00 136.08 ? 39  TYR L CD1 1 
ATOM   2921 C CD2 . TYR D 3 39  ? 121.536 128.625 147.629 1.00 136.08 ? 39  TYR L CD2 1 
ATOM   2922 C CE1 . TYR D 3 39  ? 120.110 127.854 145.422 1.00 136.08 ? 39  TYR L CE1 1 
ATOM   2923 C CE2 . TYR D 3 39  ? 122.122 128.668 146.390 1.00 136.08 ? 39  TYR L CE2 1 
ATOM   2924 C CZ  . TYR D 3 39  ? 121.403 128.280 145.292 1.00 136.08 ? 39  TYR L CZ  1 
ATOM   2925 O OH  . TYR D 3 39  ? 121.980 128.319 144.049 1.00 136.08 ? 39  TYR L OH  1 
ATOM   2926 N N   . GLN D 3 40  ? 118.130 126.615 151.367 1.00 135.85 ? 40  GLN L N   1 
ATOM   2927 C CA  . GLN D 3 40  ? 117.931 126.458 152.802 1.00 135.85 ? 40  GLN L CA  1 
ATOM   2928 C C   . GLN D 3 40  ? 119.225 126.019 153.469 1.00 135.85 ? 40  GLN L C   1 
ATOM   2929 O O   . GLN D 3 40  ? 119.925 125.137 152.968 1.00 135.85 ? 40  GLN L O   1 
ATOM   2930 C CB  . GLN D 3 40  ? 116.783 125.480 153.106 1.00 135.85 ? 40  GLN L CB  1 
ATOM   2931 C CG  . GLN D 3 40  ? 116.907 124.064 152.583 1.00 135.85 ? 40  GLN L CG  1 
ATOM   2932 C CD  . GLN D 3 40  ? 117.569 123.143 153.577 1.00 135.85 ? 40  GLN L CD  1 
ATOM   2933 O OE1 . GLN D 3 40  ? 117.451 123.333 154.785 1.00 135.85 ? 40  GLN L OE1 1 
ATOM   2934 N NE2 . GLN D 3 40  ? 118.272 122.139 153.075 1.00 135.85 ? 40  GLN L NE2 1 
ATOM   2935 N N   . GLN D 3 41  ? 119.547 126.644 154.599 1.00 136.70 ? 41  GLN L N   1 
ATOM   2936 C CA  . GLN D 3 41  ? 120.821 126.421 155.278 1.00 136.70 ? 41  GLN L CA  1 
ATOM   2937 C C   . GLN D 3 41  ? 120.567 125.779 156.638 1.00 136.70 ? 41  GLN L C   1 
ATOM   2938 O O   . GLN D 3 41  ? 120.325 126.465 157.631 1.00 136.70 ? 41  GLN L O   1 
ATOM   2939 C CB  . GLN D 3 41  ? 121.593 127.731 155.421 1.00 136.70 ? 41  GLN L CB  1 
ATOM   2940 C CG  . GLN D 3 41  ? 122.939 127.598 156.107 1.00 136.70 ? 41  GLN L CG  1 
ATOM   2941 C CD  . GLN D 3 41  ? 123.939 126.878 155.251 1.00 136.70 ? 41  GLN L CD  1 
ATOM   2942 O OE1 . GLN D 3 41  ? 124.049 127.154 154.066 1.00 136.70 ? 41  GLN L OE1 1 
ATOM   2943 N NE2 . GLN D 3 41  ? 124.672 125.946 155.842 1.00 136.70 ? 41  GLN L NE2 1 
ATOM   2944 N N   . LYS D 3 42  ? 120.629 124.457 156.687 1.00 139.03 ? 42  LYS L N   1 
ATOM   2945 C CA  . LYS D 3 42  ? 120.713 123.795 157.974 1.00 139.03 ? 42  LYS L CA  1 
ATOM   2946 C C   . LYS D 3 42  ? 122.121 123.984 158.536 1.00 139.03 ? 42  LYS L C   1 
ATOM   2947 O O   . LYS D 3 42  ? 123.092 124.031 157.779 1.00 139.03 ? 42  LYS L O   1 
ATOM   2948 C CB  . LYS D 3 42  ? 120.372 122.316 157.835 1.00 139.03 ? 42  LYS L CB  1 
ATOM   2949 C CG  . LYS D 3 42  ? 118.919 122.065 157.500 1.00 139.03 ? 42  LYS L CG  1 
ATOM   2950 C CD  . LYS D 3 42  ? 118.611 120.583 157.422 1.00 139.03 ? 42  LYS L CD  1 
ATOM   2951 C CE  . LYS D 3 42  ? 117.129 120.350 157.192 1.00 139.03 ? 42  LYS L CE  1 
ATOM   2952 N NZ  . LYS D 3 42  ? 116.696 120.840 155.857 1.00 139.03 ? 42  LYS L NZ  1 
ATOM   2953 N N   . PRO D 3 43  ? 122.267 124.098 159.858 1.00 140.36 ? 43  PRO L N   1 
ATOM   2954 C CA  . PRO D 3 43  ? 123.553 124.510 160.433 1.00 140.36 ? 43  PRO L CA  1 
ATOM   2955 C C   . PRO D 3 43  ? 124.633 123.438 160.452 1.00 140.36 ? 43  PRO L C   1 
ATOM   2956 O O   . PRO D 3 43  ? 125.638 123.623 161.142 1.00 140.36 ? 43  PRO L O   1 
ATOM   2957 C CB  . PRO D 3 43  ? 123.168 124.908 161.865 1.00 140.36 ? 43  PRO L CB  1 
ATOM   2958 C CG  . PRO D 3 43  ? 121.987 124.096 162.168 1.00 140.36 ? 43  PRO L CG  1 
ATOM   2959 C CD  . PRO D 3 43  ? 121.222 123.993 160.892 1.00 140.36 ? 43  PRO L CD  1 
ATOM   2960 N N   . GLY D 3 44  ? 124.475 122.334 159.731 1.00 135.90 ? 44  GLY L N   1 
ATOM   2961 C CA  . GLY D 3 44  ? 125.516 121.331 159.686 1.00 135.90 ? 44  GLY L CA  1 
ATOM   2962 C C   . GLY D 3 44  ? 126.229 121.241 158.353 1.00 135.90 ? 44  GLY L C   1 
ATOM   2963 O O   . GLY D 3 44  ? 127.382 120.804 158.300 1.00 135.90 ? 44  GLY L O   1 
ATOM   2964 N N   . GLU D 3 45  ? 125.577 121.660 157.278 1.00 136.82 ? 45  GLU L N   1 
ATOM   2965 C CA  . GLU D 3 45  ? 126.029 121.361 155.929 1.00 136.82 ? 45  GLU L CA  1 
ATOM   2966 C C   . GLU D 3 45  ? 125.907 122.578 155.023 1.00 136.82 ? 45  GLU L C   1 
ATOM   2967 O O   . GLU D 3 45  ? 125.196 123.534 155.349 1.00 136.82 ? 45  GLU L O   1 
ATOM   2968 C CB  . GLU D 3 45  ? 125.217 120.186 155.356 1.00 136.82 ? 45  GLU L CB  1 
ATOM   2969 C CG  . GLU D 3 45  ? 123.770 120.487 155.027 1.00 136.82 ? 45  GLU L CG  1 
ATOM   2970 C CD  . GLU D 3 45  ? 122.831 120.199 156.176 1.00 136.82 ? 45  GLU L CD  1 
ATOM   2971 O OE1 . GLU D 3 45  ? 123.297 120.122 157.332 1.00 136.82 ? 45  GLU L OE1 1 
ATOM   2972 O OE2 . GLU D 3 45  ? 121.626 120.017 155.911 1.00 136.82 ? 45  GLU L OE2 1 
ATOM   2973 N N   . PRO D 3 46  ? 126.621 122.590 153.895 1.00 132.89 ? 46  PRO L N   1 
ATOM   2974 C CA  . PRO D 3 46  ? 126.365 123.608 152.880 1.00 132.89 ? 46  PRO L CA  1 
ATOM   2975 C C   . PRO D 3 46  ? 124.977 123.447 152.299 1.00 132.89 ? 46  PRO L C   1 
ATOM   2976 O O   . PRO D 3 46  ? 124.414 122.336 152.296 1.00 132.89 ? 46  PRO L O   1 
ATOM   2977 C CB  . PRO D 3 46  ? 127.459 123.338 151.834 1.00 132.89 ? 46  PRO L CB  1 
ATOM   2978 C CG  . PRO D 3 46  ? 127.898 121.957 152.080 1.00 132.89 ? 46  PRO L CG  1 
ATOM   2979 C CD  . PRO D 3 46  ? 127.814 121.796 153.554 1.00 132.89 ? 46  PRO L CD  1 
ATOM   2980 N N   . PRO D 3 47  ? 124.369 124.545 151.779 1.00 126.33 ? 47  PRO L N   1 
ATOM   2981 C CA  . PRO D 3 47  ? 122.911 124.556 151.599 1.00 126.33 ? 47  PRO L CA  1 
ATOM   2982 C C   . PRO D 3 47  ? 122.396 123.707 150.452 1.00 126.33 ? 47  PRO L C   1 
ATOM   2983 O O   . PRO D 3 47  ? 123.164 123.087 149.713 1.00 126.33 ? 47  PRO L O   1 
ATOM   2984 C CB  . PRO D 3 47  ? 122.609 126.037 151.349 1.00 126.33 ? 47  PRO L CB  1 
ATOM   2985 C CG  . PRO D 3 47  ? 123.810 126.542 150.702 1.00 126.33 ? 47  PRO L CG  1 
ATOM   2986 C CD  . PRO D 3 47  ? 124.969 125.804 151.293 1.00 126.33 ? 47  PRO L CD  1 
ATOM   2987 N N   . LYS D 3 48  ? 121.077 123.685 150.306 1.00 128.33 ? 48  LYS L N   1 
ATOM   2988 C CA  . LYS D 3 48  ? 120.393 122.900 149.291 1.00 128.33 ? 48  LYS L CA  1 
ATOM   2989 C C   . LYS D 3 48  ? 119.332 123.776 148.652 1.00 128.33 ? 48  LYS L C   1 
ATOM   2990 O O   . LYS D 3 48  ? 118.676 124.561 149.343 1.00 128.33 ? 48  LYS L O   1 
ATOM   2991 C CB  . LYS D 3 48  ? 119.750 121.656 149.907 1.00 128.33 ? 48  LYS L CB  1 
ATOM   2992 C CG  . LYS D 3 48  ? 119.100 120.715 148.920 1.00 128.33 ? 48  LYS L CG  1 
ATOM   2993 C CD  . LYS D 3 48  ? 118.421 119.579 149.650 1.00 128.33 ? 48  LYS L CD  1 
ATOM   2994 C CE  . LYS D 3 48  ? 119.449 118.630 150.233 1.00 128.33 ? 48  LYS L CE  1 
ATOM   2995 N NZ  . LYS D 3 48  ? 118.803 117.447 150.852 1.00 128.33 ? 48  LYS L NZ  1 
ATOM   2996 N N   . LEU D 3 49  ? 119.158 123.647 147.340 1.00 133.76 ? 49  LEU L N   1 
ATOM   2997 C CA  . LEU D 3 49  ? 118.185 124.500 146.686 1.00 133.76 ? 49  LEU L CA  1 
ATOM   2998 C C   . LEU D 3 49  ? 116.783 123.935 146.817 1.00 133.76 ? 49  LEU L C   1 
ATOM   2999 O O   . LEU D 3 49  ? 116.540 122.881 147.411 1.00 133.76 ? 49  LEU L O   1 
ATOM   3000 C CB  . LEU D 3 49  ? 118.509 124.718 145.208 1.00 133.76 ? 49  LEU L CB  1 
ATOM   3001 C CG  . LEU D 3 49  ? 118.655 123.705 144.071 1.00 133.76 ? 49  LEU L CG  1 
ATOM   3002 C CD1 . LEU D 3 49  ? 117.343 123.170 143.522 1.00 133.76 ? 49  LEU L CD1 1 
ATOM   3003 C CD2 . LEU D 3 49  ? 119.324 124.482 142.970 1.00 133.76 ? 49  LEU L CD2 1 
ATOM   3004 N N   . LEU D 3 50  ? 115.857 124.680 146.229 1.00 146.08 ? 50  LEU L N   1 
ATOM   3005 C CA  . LEU D 3 50  ? 114.508 124.211 145.960 1.00 146.08 ? 50  LEU L CA  1 
ATOM   3006 C C   . LEU D 3 50  ? 113.976 124.930 144.720 1.00 146.08 ? 50  LEU L C   1 
ATOM   3007 O O   . LEU D 3 50  ? 114.750 125.290 143.826 1.00 146.08 ? 50  LEU L O   1 
ATOM   3008 C CB  . LEU D 3 50  ? 113.628 124.326 147.211 1.00 146.08 ? 50  LEU L CB  1 
ATOM   3009 C CG  . LEU D 3 50  ? 113.536 125.588 148.054 1.00 146.08 ? 50  LEU L CG  1 
ATOM   3010 C CD1 . LEU D 3 50  ? 112.320 126.400 147.682 1.00 146.08 ? 50  LEU L CD1 1 
ATOM   3011 C CD2 . LEU D 3 50  ? 113.521 125.208 149.529 1.00 146.08 ? 50  LEU L CD2 1 
ATOM   3012 N N   . ILE D 3 51  ? 112.667 125.152 144.662 1.00 150.54 ? 51  ILE L N   1 
ATOM   3013 C CA  . ILE D 3 51  ? 111.772 125.236 143.508 1.00 150.54 ? 51  ILE L CA  1 
ATOM   3014 C C   . ILE D 3 51  ? 112.101 126.217 142.373 1.00 150.54 ? 51  ILE L C   1 
ATOM   3015 O O   . ILE D 3 51  ? 111.219 126.539 141.566 1.00 150.54 ? 51  ILE L O   1 
ATOM   3016 C CB  . ILE D 3 51  ? 110.362 125.508 144.045 1.00 150.54 ? 51  ILE L CB  1 
ATOM   3017 C CG1 . ILE D 3 51  ? 110.275 126.894 144.657 1.00 150.54 ? 51  ILE L CG1 1 
ATOM   3018 C CG2 . ILE D 3 51  ? 110.048 124.531 145.166 1.00 150.54 ? 51  ILE L CG2 1 
ATOM   3019 C CD1 . ILE D 3 51  ? 108.877 127.219 145.075 1.00 150.54 ? 51  ILE L CD1 1 
ATOM   3020 N N   . SER D 3 52  ? 113.345 126.712 142.321 1.00 148.90 ? 52  SER L N   1 
ATOM   3021 C CA  . SER D 3 52  ? 113.899 127.728 141.419 1.00 148.90 ? 52  SER L CA  1 
ATOM   3022 C C   . SER D 3 52  ? 113.489 127.698 139.950 1.00 148.90 ? 52  SER L C   1 
ATOM   3023 O O   . SER D 3 52  ? 113.100 126.648 139.437 1.00 148.90 ? 52  SER L O   1 
ATOM   3024 C CB  . SER D 3 52  ? 115.416 127.615 141.425 1.00 148.90 ? 52  SER L CB  1 
ATOM   3025 O OG  . SER D 3 52  ? 115.971 128.528 140.494 1.00 148.90 ? 52  SER L OG  1 
ATOM   3026 N N   . GLU D 3 53  ? 113.633 128.858 139.285 1.00 155.49 ? 53  GLU L N   1 
ATOM   3027 C CA  . GLU D 3 53  ? 112.968 129.223 138.024 1.00 155.49 ? 53  GLU L CA  1 
ATOM   3028 C C   . GLU D 3 53  ? 111.453 129.200 138.196 1.00 155.49 ? 53  GLU L C   1 
ATOM   3029 O O   . GLU D 3 53  ? 110.715 128.622 137.399 1.00 155.49 ? 53  GLU L O   1 
ATOM   3030 C CB  . GLU D 3 53  ? 113.403 128.362 136.833 1.00 155.49 ? 53  GLU L CB  1 
ATOM   3031 C CG  . GLU D 3 53  ? 114.827 128.578 136.371 1.00 155.49 ? 53  GLU L CG  1 
ATOM   3032 C CD  . GLU D 3 53  ? 115.157 127.740 135.150 1.00 155.49 ? 53  GLU L CD  1 
ATOM   3033 O OE1 . GLU D 3 53  ? 114.314 126.904 134.763 1.00 155.49 ? 53  GLU L OE1 1 
ATOM   3034 O OE2 . GLU D 3 53  ? 116.250 127.920 134.572 1.00 155.49 ? 53  GLU L OE2 1 
ATOM   3035 N N   . GLY D 3 54  ? 110.997 129.864 139.250 1.00 152.13 ? 54  GLY L N   1 
ATOM   3036 C CA  . GLY D 3 54  ? 109.588 130.041 139.520 1.00 152.13 ? 54  GLY L CA  1 
ATOM   3037 C C   . GLY D 3 54  ? 108.933 128.879 140.232 1.00 152.13 ? 54  GLY L C   1 
ATOM   3038 O O   . GLY D 3 54  ? 108.743 128.926 141.449 1.00 152.13 ? 54  GLY L O   1 
ATOM   3039 N N   . ASN D 3 55  ? 108.587 127.827 139.500 1.00 154.38 ? 55  ASN L N   1 
ATOM   3040 C CA  . ASN D 3 55  ? 107.751 126.767 140.050 1.00 154.38 ? 55  ASN L CA  1 
ATOM   3041 C C   . ASN D 3 55  ? 108.207 125.394 139.567 1.00 154.38 ? 55  ASN L C   1 
ATOM   3042 O O   . ASN D 3 55  ? 107.403 124.570 139.131 1.00 154.38 ? 55  ASN L O   1 
ATOM   3043 C CB  . ASN D 3 55  ? 106.286 127.012 139.695 1.00 154.38 ? 55  ASN L CB  1 
ATOM   3044 C CG  . ASN D 3 55  ? 105.689 128.186 140.451 1.00 154.38 ? 55  ASN L CG  1 
ATOM   3045 O OD1 . ASN D 3 55  ? 105.902 128.340 141.654 1.00 154.38 ? 55  ASN L OD1 1 
ATOM   3046 N ND2 . ASN D 3 55  ? 104.945 129.030 139.743 1.00 154.38 ? 55  ASN L ND2 1 
ATOM   3047 N N   . THR D 3 56  ? 109.509 125.123 139.622 1.00 153.33 ? 56  THR L N   1 
ATOM   3048 C CA  . THR D 3 56  ? 109.967 123.839 139.100 1.00 153.33 ? 56  THR L CA  1 
ATOM   3049 C C   . THR D 3 56  ? 109.888 122.711 140.125 1.00 153.33 ? 56  THR L C   1 
ATOM   3050 O O   . THR D 3 56  ? 109.404 121.625 139.789 1.00 153.33 ? 56  THR L O   1 
ATOM   3051 C CB  . THR D 3 56  ? 111.387 123.961 138.556 1.00 153.33 ? 56  THR L CB  1 
ATOM   3052 O OG1 . THR D 3 56  ? 112.243 124.498 139.571 1.00 153.33 ? 56  THR L OG1 1 
ATOM   3053 C CG2 . THR D 3 56  ? 111.404 124.842 137.314 1.00 153.33 ? 56  THR L CG2 1 
ATOM   3054 N N   . LEU D 3 57  ? 110.352 122.956 141.359 1.00 147.94 ? 57  LEU L N   1 
ATOM   3055 C CA  . LEU D 3 57  ? 110.299 122.011 142.485 1.00 147.94 ? 57  LEU L CA  1 
ATOM   3056 C C   . LEU D 3 57  ? 111.047 120.715 142.151 1.00 147.94 ? 57  LEU L C   1 
ATOM   3057 O O   . LEU D 3 57  ? 110.460 119.677 141.846 1.00 147.94 ? 57  LEU L O   1 
ATOM   3058 C CB  . LEU D 3 57  ? 108.851 121.757 142.933 1.00 147.94 ? 57  LEU L CB  1 
ATOM   3059 C CG  . LEU D 3 57  ? 108.569 121.209 144.340 1.00 147.94 ? 57  LEU L CG  1 
ATOM   3060 C CD1 . LEU D 3 57  ? 107.248 121.774 144.831 1.00 147.94 ? 57  LEU L CD1 1 
ATOM   3061 C CD2 . LEU D 3 57  ? 108.536 119.690 144.439 1.00 147.94 ? 57  LEU L CD2 1 
ATOM   3062 N N   . ARG D 3 58  ? 112.369 120.853 142.102 1.00 145.14 ? 58  ARG L N   1 
ATOM   3063 C CA  . ARG D 3 58  ? 113.245 119.731 141.795 1.00 145.14 ? 58  ARG L CA  1 
ATOM   3064 C C   . ARG D 3 58  ? 113.096 118.628 142.839 1.00 145.14 ? 58  ARG L C   1 
ATOM   3065 O O   . ARG D 3 58  ? 112.908 118.922 144.023 1.00 145.14 ? 58  ARG L O   1 
ATOM   3066 C CB  . ARG D 3 58  ? 114.691 120.213 141.716 1.00 145.14 ? 58  ARG L CB  1 
ATOM   3067 C CG  . ARG D 3 58  ? 114.862 121.064 140.505 1.00 145.14 ? 58  ARG L CG  1 
ATOM   3068 C CD  . ARG D 3 58  ? 116.232 121.632 140.290 1.00 145.14 ? 58  ARG L CD  1 
ATOM   3069 N NE  . ARG D 3 58  ? 116.147 122.441 139.086 1.00 145.14 ? 58  ARG L NE  1 
ATOM   3070 C CZ  . ARG D 3 58  ? 115.791 123.719 139.082 1.00 145.14 ? 58  ARG L CZ  1 
ATOM   3071 N NH1 . ARG D 3 58  ? 115.519 124.343 140.221 1.00 145.14 ? 58  ARG L NH1 1 
ATOM   3072 N NH2 . ARG D 3 58  ? 115.705 124.375 137.938 1.00 145.14 ? 58  ARG L NH2 1 
ATOM   3073 N N   . PRO D 3 59  ? 113.149 117.359 142.433 1.00 146.12 ? 59  PRO L N   1 
ATOM   3074 C CA  . PRO D 3 59  ? 112.798 116.271 143.350 1.00 146.12 ? 59  PRO L CA  1 
ATOM   3075 C C   . PRO D 3 59  ? 113.833 116.078 144.442 1.00 146.12 ? 59  PRO L C   1 
ATOM   3076 O O   . PRO D 3 59  ? 115.004 116.433 144.299 1.00 146.12 ? 59  PRO L O   1 
ATOM   3077 C CB  . PRO D 3 59  ? 112.728 115.047 142.434 1.00 146.12 ? 59  PRO L CB  1 
ATOM   3078 C CG  . PRO D 3 59  ? 113.627 115.382 141.306 1.00 146.12 ? 59  PRO L CG  1 
ATOM   3079 C CD  . PRO D 3 59  ? 113.482 116.855 141.090 1.00 146.12 ? 59  PRO L CD  1 
ATOM   3080 N N   . GLY D 3 60  ? 113.374 115.501 145.546 1.00 148.87 ? 60  GLY L N   1 
ATOM   3081 C CA  . GLY D 3 60  ? 114.109 115.468 146.786 1.00 148.87 ? 60  GLY L CA  1 
ATOM   3082 C C   . GLY D 3 60  ? 113.525 116.372 147.845 1.00 148.87 ? 60  GLY L C   1 
ATOM   3083 O O   . GLY D 3 60  ? 113.785 116.163 149.036 1.00 148.87 ? 60  GLY L O   1 
ATOM   3084 N N   . VAL D 3 61  ? 112.738 117.364 147.444 1.00 151.07 ? 61  VAL L N   1 
ATOM   3085 C CA  . VAL D 3 61  ? 112.063 118.260 148.376 1.00 151.07 ? 61  VAL L CA  1 
ATOM   3086 C C   . VAL D 3 61  ? 110.595 117.841 148.344 1.00 151.07 ? 61  VAL L C   1 
ATOM   3087 O O   . VAL D 3 61  ? 110.113 117.385 147.295 1.00 151.07 ? 61  VAL L O   1 
ATOM   3088 C CB  . VAL D 3 61  ? 112.321 119.736 147.997 1.00 151.07 ? 61  VAL L CB  1 
ATOM   3089 C CG1 . VAL D 3 61  ? 111.577 120.166 146.738 1.00 151.07 ? 61  VAL L CG1 1 
ATOM   3090 C CG2 . VAL D 3 61  ? 112.052 120.685 149.142 1.00 151.07 ? 61  VAL L CG2 1 
ATOM   3091 N N   . PRO D 3 62  ? 109.872 117.865 149.461 1.00 156.91 ? 62  PRO L N   1 
ATOM   3092 C CA  . PRO D 3 62  ? 108.461 117.471 149.423 1.00 156.91 ? 62  PRO L CA  1 
ATOM   3093 C C   . PRO D 3 62  ? 107.607 118.527 148.743 1.00 156.91 ? 62  PRO L C   1 
ATOM   3094 O O   . PRO D 3 62  ? 108.026 119.660 148.503 1.00 156.91 ? 62  PRO L O   1 
ATOM   3095 C CB  . PRO D 3 62  ? 108.089 117.312 150.898 1.00 156.91 ? 62  PRO L CB  1 
ATOM   3096 C CG  . PRO D 3 62  ? 109.071 118.128 151.624 1.00 156.91 ? 62  PRO L CG  1 
ATOM   3097 C CD  . PRO D 3 62  ? 110.345 118.002 150.847 1.00 156.91 ? 62  PRO L CD  1 
ATOM   3098 N N   . SER D 3 63  ? 106.373 118.130 148.437 1.00 159.18 ? 63  SER L N   1 
ATOM   3099 C CA  . SER D 3 63  ? 105.432 118.976 147.715 1.00 159.18 ? 63  SER L CA  1 
ATOM   3100 C C   . SER D 3 63  ? 104.749 120.008 148.600 1.00 159.18 ? 63  SER L C   1 
ATOM   3101 O O   . SER D 3 63  ? 103.884 120.741 148.111 1.00 159.18 ? 63  SER L O   1 
ATOM   3102 C CB  . SER D 3 63  ? 104.370 118.112 147.039 1.00 159.18 ? 63  SER L CB  1 
ATOM   3103 O OG  . SER D 3 63  ? 103.574 117.461 148.011 1.00 159.18 ? 63  SER L OG  1 
ATOM   3104 N N   . ARG D 3 64  ? 105.103 120.078 149.881 1.00 162.30 ? 64  ARG L N   1 
ATOM   3105 C CA  . ARG D 3 64  ? 104.501 121.063 150.764 1.00 162.30 ? 64  ARG L CA  1 
ATOM   3106 C C   . ARG D 3 64  ? 105.000 122.477 150.490 1.00 162.30 ? 64  ARG L C   1 
ATOM   3107 O O   . ARG D 3 64  ? 104.284 123.435 150.783 1.00 162.30 ? 64  ARG L O   1 
ATOM   3108 C CB  . ARG D 3 64  ? 104.757 120.669 152.219 1.00 162.30 ? 64  ARG L CB  1 
ATOM   3109 C CG  . ARG D 3 64  ? 106.223 120.581 152.599 1.00 162.30 ? 64  ARG L CG  1 
ATOM   3110 C CD  . ARG D 3 64  ? 106.393 120.145 154.044 1.00 162.30 ? 64  ARG L CD  1 
ATOM   3111 N NE  . ARG D 3 64  ? 107.796 120.131 154.444 1.00 162.30 ? 64  ARG L NE  1 
ATOM   3112 C CZ  . ARG D 3 64  ? 108.225 119.801 155.657 1.00 162.30 ? 64  ARG L CZ  1 
ATOM   3113 N NH1 . ARG D 3 64  ? 107.358 119.451 156.596 1.00 162.30 ? 64  ARG L NH1 1 
ATOM   3114 N NH2 . ARG D 3 64  ? 109.521 119.821 155.932 1.00 162.30 ? 64  ARG L NH2 1 
ATOM   3115 N N   . PHE D 3 65  ? 106.187 122.631 149.913 1.00 155.24 ? 65  PHE L N   1 
ATOM   3116 C CA  . PHE D 3 65  ? 106.760 123.949 149.684 1.00 155.24 ? 65  PHE L CA  1 
ATOM   3117 C C   . PHE D 3 65  ? 106.116 124.626 148.482 1.00 155.24 ? 65  PHE L C   1 
ATOM   3118 O O   . PHE D 3 65  ? 105.663 123.967 147.543 1.00 155.24 ? 65  PHE L O   1 
ATOM   3119 C CB  . PHE D 3 65  ? 108.263 123.831 149.470 1.00 155.24 ? 65  PHE L CB  1 
ATOM   3120 C CG  . PHE D 3 65  ? 109.002 123.398 150.689 1.00 155.24 ? 65  PHE L CG  1 
ATOM   3121 C CD1 . PHE D 3 65  ? 109.417 124.325 151.624 1.00 155.24 ? 65  PHE L CD1 1 
ATOM   3122 C CD2 . PHE D 3 65  ? 109.246 122.058 150.921 1.00 155.24 ? 65  PHE L CD2 1 
ATOM   3123 C CE1 . PHE D 3 65  ? 110.094 123.927 152.756 1.00 155.24 ? 65  PHE L CE1 1 
ATOM   3124 C CE2 . PHE D 3 65  ? 109.919 121.652 152.053 1.00 155.24 ? 65  PHE L CE2 1 
ATOM   3125 C CZ  . PHE D 3 65  ? 110.342 122.589 152.971 1.00 155.24 ? 65  PHE L CZ  1 
ATOM   3126 N N   . SER D 3 66  ? 106.088 125.959 148.512 1.00 154.19 ? 66  SER L N   1 
ATOM   3127 C CA  . SER D 3 66  ? 105.473 126.706 147.424 1.00 154.19 ? 66  SER L CA  1 
ATOM   3128 C C   . SER D 3 66  ? 106.026 128.122 147.379 1.00 154.19 ? 66  SER L C   1 
ATOM   3129 O O   . SER D 3 66  ? 106.469 128.676 148.387 1.00 154.19 ? 66  SER L O   1 
ATOM   3130 C CB  . SER D 3 66  ? 103.950 126.754 147.576 1.00 154.19 ? 66  SER L CB  1 
ATOM   3131 O OG  . SER D 3 66  ? 103.589 127.508 148.719 1.00 154.19 ? 66  SER L OG  1 
ATOM   3132 N N   . SER D 3 67  ? 105.970 128.713 146.191 1.00 150.46 ? 67  SER L N   1 
ATOM   3133 C CA  . SER D 3 67  ? 106.160 130.149 146.070 1.00 150.46 ? 67  SER L CA  1 
ATOM   3134 C C   . SER D 3 67  ? 105.359 130.632 144.877 1.00 150.46 ? 67  SER L C   1 
ATOM   3135 O O   . SER D 3 67  ? 104.862 129.842 144.072 1.00 150.46 ? 67  SER L O   1 
ATOM   3136 C CB  . SER D 3 67  ? 107.624 130.539 145.880 1.00 150.46 ? 67  SER L CB  1 
ATOM   3137 O OG  . SER D 3 67  ? 108.017 130.317 144.540 1.00 150.46 ? 67  SER L OG  1 
ATOM   3138 N N   . SER D 3 68  ? 105.256 131.949 144.772 1.00 150.53 ? 68  SER L N   1 
ATOM   3139 C CA  . SER D 3 68  ? 104.716 132.587 143.584 1.00 150.53 ? 68  SER L CA  1 
ATOM   3140 C C   . SER D 3 68  ? 105.315 133.977 143.486 1.00 150.53 ? 68  SER L C   1 
ATOM   3141 O O   . SER D 3 68  ? 106.004 134.447 144.395 1.00 150.53 ? 68  SER L O   1 
ATOM   3142 C CB  . SER D 3 68  ? 103.187 132.653 143.614 1.00 150.53 ? 68  SER L CB  1 
ATOM   3143 O OG  . SER D 3 68  ? 102.737 133.527 144.629 1.00 150.53 ? 68  SER L OG  1 
ATOM   3144 N N   . GLY D 3 69  ? 105.059 134.628 142.370 1.00 155.43 ? 69  GLY L N   1 
ATOM   3145 C CA  . GLY D 3 69  ? 105.465 136.003 142.203 1.00 155.43 ? 69  GLY L CA  1 
ATOM   3146 C C   . GLY D 3 69  ? 105.929 136.273 140.788 1.00 155.43 ? 69  GLY L C   1 
ATOM   3147 O O   . GLY D 3 69  ? 105.760 135.458 139.887 1.00 155.43 ? 69  GLY L O   1 
ATOM   3148 N N   . TYR D 3 70  ? 106.536 137.441 140.638 1.00 164.10 ? 70  TYR L N   1 
ATOM   3149 C CA  . TYR D 3 70  ? 106.916 138.028 139.360 1.00 164.10 ? 70  TYR L CA  1 
ATOM   3150 C C   . TYR D 3 70  ? 107.886 139.155 139.715 1.00 164.10 ? 70  TYR L C   1 
ATOM   3151 O O   . TYR D 3 70  ? 108.282 139.295 140.876 1.00 164.10 ? 70  TYR L O   1 
ATOM   3152 C CB  . TYR D 3 70  ? 105.654 138.472 138.603 1.00 164.10 ? 70  TYR L CB  1 
ATOM   3153 C CG  . TYR D 3 70  ? 105.822 138.969 137.184 1.00 164.10 ? 70  TYR L CG  1 
ATOM   3154 C CD1 . TYR D 3 70  ? 106.115 138.098 136.143 1.00 164.10 ? 70  TYR L CD1 1 
ATOM   3155 C CD2 . TYR D 3 70  ? 105.659 140.316 136.888 1.00 164.10 ? 70  TYR L CD2 1 
ATOM   3156 C CE1 . TYR D 3 70  ? 106.258 138.564 134.849 1.00 164.10 ? 70  TYR L CE1 1 
ATOM   3157 C CE2 . TYR D 3 70  ? 105.805 140.789 135.607 1.00 164.10 ? 70  TYR L CE2 1 
ATOM   3158 C CZ  . TYR D 3 70  ? 106.104 139.911 134.591 1.00 164.10 ? 70  TYR L CZ  1 
ATOM   3159 O OH  . TYR D 3 70  ? 106.243 140.395 133.311 1.00 164.10 ? 70  TYR L OH  1 
ATOM   3160 N N   . GLY D 3 71  ? 108.280 139.941 138.713 1.00 163.86 ? 71  GLY L N   1 
ATOM   3161 C CA  . GLY D 3 71  ? 109.174 141.072 138.868 1.00 163.86 ? 71  GLY L CA  1 
ATOM   3162 C C   . GLY D 3 71  ? 108.862 142.034 139.996 1.00 163.86 ? 71  GLY L C   1 
ATOM   3163 O O   . GLY D 3 71  ? 107.760 142.585 140.074 1.00 163.86 ? 71  GLY L O   1 
ATOM   3164 N N   . THR D 3 72  ? 109.843 142.168 140.896 1.00 162.60 ? 72  THR L N   1 
ATOM   3165 C CA  . THR D 3 72  ? 109.895 142.959 142.128 1.00 162.60 ? 72  THR L CA  1 
ATOM   3166 C C   . THR D 3 72  ? 109.011 142.427 143.252 1.00 162.60 ? 72  THR L C   1 
ATOM   3167 O O   . THR D 3 72  ? 108.879 143.116 144.272 1.00 162.60 ? 72  THR L O   1 
ATOM   3168 C CB  . THR D 3 72  ? 109.561 144.448 141.924 1.00 162.60 ? 72  THR L CB  1 
ATOM   3169 O OG1 . THR D 3 72  ? 108.178 144.596 141.581 1.00 162.60 ? 72  THR L OG1 1 
ATOM   3170 C CG2 . THR D 3 72  ? 110.412 145.058 140.815 1.00 162.60 ? 72  THR L CG2 1 
ATOM   3171 N N   . ASP D 3 73  ? 108.419 141.231 143.130 1.00 164.51 ? 73  ASP L N   1 
ATOM   3172 C CA  . ASP D 3 73  ? 107.626 140.703 144.247 1.00 164.51 ? 73  ASP L CA  1 
ATOM   3173 C C   . ASP D 3 73  ? 107.558 139.180 144.216 1.00 164.51 ? 73  ASP L C   1 
ATOM   3174 O O   . ASP D 3 73  ? 107.008 138.599 143.276 1.00 164.51 ? 73  ASP L O   1 
ATOM   3175 C CB  . ASP D 3 73  ? 106.222 141.315 144.264 1.00 164.51 ? 73  ASP L CB  1 
ATOM   3176 C CG  . ASP D 3 73  ? 105.549 141.312 142.907 1.00 164.51 ? 73  ASP L CG  1 
ATOM   3177 O OD1 . ASP D 3 73  ? 106.200 140.962 141.905 1.00 164.51 ? 73  ASP L OD1 1 
ATOM   3178 O OD2 . ASP D 3 73  ? 104.356 141.671 142.836 1.00 164.51 ? 73  ASP L OD2 1 
ATOM   3179 N N   . PHE D 3 74  ? 108.073 138.535 145.261 1.00 157.42 ? 74  PHE L N   1 
ATOM   3180 C CA  . PHE D 3 74  ? 107.963 137.092 145.368 1.00 157.42 ? 74  PHE L CA  1 
ATOM   3181 C C   . PHE D 3 74  ? 107.579 136.709 146.784 1.00 157.42 ? 74  PHE L C   1 
ATOM   3182 O O   . PHE D 3 74  ? 108.143 137.229 147.749 1.00 157.42 ? 74  PHE L O   1 
ATOM   3183 C CB  . PHE D 3 74  ? 109.264 136.415 144.985 1.00 157.42 ? 74  PHE L CB  1 
ATOM   3184 C CG  . PHE D 3 74  ? 109.608 136.558 143.542 1.00 157.42 ? 74  PHE L CG  1 
ATOM   3185 C CD1 . PHE D 3 74  ? 109.049 135.712 142.599 1.00 157.42 ? 74  PHE L CD1 1 
ATOM   3186 C CD2 . PHE D 3 74  ? 110.476 137.548 143.121 1.00 157.42 ? 74  PHE L CD2 1 
ATOM   3187 C CE1 . PHE D 3 74  ? 109.361 135.842 141.262 1.00 157.42 ? 74  PHE L CE1 1 
ATOM   3188 C CE2 . PHE D 3 74  ? 110.794 137.680 141.789 1.00 157.42 ? 74  PHE L CE2 1 
ATOM   3189 C CZ  . PHE D 3 74  ? 110.238 136.826 140.857 1.00 157.42 ? 74  PHE L CZ  1 
ATOM   3190 N N   . VAL D 3 75  ? 106.637 135.782 146.902 1.00 150.12 ? 75  VAL L N   1 
ATOM   3191 C CA  . VAL D 3 75  ? 106.167 135.303 148.193 1.00 150.12 ? 75  VAL L CA  1 
ATOM   3192 C C   . VAL D 3 75  ? 106.423 133.803 148.270 1.00 150.12 ? 75  VAL L C   1 
ATOM   3193 O O   . VAL D 3 75  ? 106.216 133.076 147.292 1.00 150.12 ? 75  VAL L O   1 
ATOM   3194 C CB  . VAL D 3 75  ? 104.684 135.669 148.424 1.00 150.12 ? 75  VAL L CB  1 
ATOM   3195 C CG1 . VAL D 3 75  ? 103.773 135.132 147.323 1.00 150.12 ? 75  VAL L CG1 1 
ATOM   3196 C CG2 . VAL D 3 75  ? 104.209 135.196 149.783 1.00 150.12 ? 75  VAL L CG2 1 
ATOM   3197 N N   . PHE D 3 76  ? 106.940 133.358 149.412 1.00 150.44 ? 76  PHE L N   1 
ATOM   3198 C CA  . PHE D 3 76  ? 107.338 131.980 149.652 1.00 150.44 ? 76  PHE L CA  1 
ATOM   3199 C C   . PHE D 3 76  ? 106.625 131.475 150.896 1.00 150.44 ? 76  PHE L C   1 
ATOM   3200 O O   . PHE D 3 76  ? 106.675 132.127 151.946 1.00 150.44 ? 76  PHE L O   1 
ATOM   3201 C CB  . PHE D 3 76  ? 108.856 131.895 149.828 1.00 150.44 ? 76  PHE L CB  1 
ATOM   3202 C CG  . PHE D 3 76  ? 109.360 130.523 150.142 1.00 150.44 ? 76  PHE L CG  1 
ATOM   3203 C CD1 . PHE D 3 76  ? 109.417 129.556 149.163 1.00 150.44 ? 76  PHE L CD1 1 
ATOM   3204 C CD2 . PHE D 3 76  ? 109.806 130.209 151.415 1.00 150.44 ? 76  PHE L CD2 1 
ATOM   3205 C CE1 . PHE D 3 76  ? 109.879 128.293 149.451 1.00 150.44 ? 76  PHE L CE1 1 
ATOM   3206 C CE2 . PHE D 3 76  ? 110.280 128.946 151.706 1.00 150.44 ? 76  PHE L CE2 1 
ATOM   3207 C CZ  . PHE D 3 76  ? 110.319 127.990 150.721 1.00 150.44 ? 76  PHE L CZ  1 
ATOM   3208 N N   . THR D 3 77  ? 105.968 130.321 150.782 1.00 157.22 ? 77  THR L N   1 
ATOM   3209 C CA  . THR D 3 77  ? 105.188 129.802 151.897 1.00 157.22 ? 77  THR L CA  1 
ATOM   3210 C C   . THR D 3 77  ? 105.041 128.296 151.757 1.00 157.22 ? 77  THR L C   1 
ATOM   3211 O O   . THR D 3 77  ? 105.208 127.737 150.671 1.00 157.22 ? 77  THR L O   1 
ATOM   3212 C CB  . THR D 3 77  ? 103.815 130.473 151.981 1.00 157.22 ? 77  THR L CB  1 
ATOM   3213 O OG1 . THR D 3 77  ? 103.150 130.033 153.167 1.00 157.22 ? 77  THR L OG1 1 
ATOM   3214 C CG2 . THR D 3 77  ? 102.969 130.143 150.762 1.00 157.22 ? 77  THR L CG2 1 
ATOM   3215 N N   . ILE D 3 78  ? 104.741 127.630 152.871 1.00 162.39 ? 78  ILE L N   1 
ATOM   3216 C CA  . ILE D 3 78  ? 104.739 126.178 152.785 1.00 162.39 ? 78  ILE L CA  1 
ATOM   3217 C C   . ILE D 3 78  ? 103.340 125.605 152.981 1.00 162.39 ? 78  ILE L C   1 
ATOM   3218 O O   . ILE D 3 78  ? 102.620 125.381 152.001 1.00 162.39 ? 78  ILE L O   1 
ATOM   3219 C CB  . ILE D 3 78  ? 105.711 125.575 153.822 1.00 162.39 ? 78  ILE L CB  1 
ATOM   3220 C CG1 . ILE D 3 78  ? 107.117 126.172 153.703 1.00 162.39 ? 78  ILE L CG1 1 
ATOM   3221 C CG2 . ILE D 3 78  ? 105.826 124.080 153.646 1.00 162.39 ? 78  ILE L CG2 1 
ATOM   3222 C CD1 . ILE D 3 78  ? 107.453 127.240 154.732 1.00 162.39 ? 78  ILE L CD1 1 
ATOM   3223 N N   . GLU D 3 79  ? 102.888 125.525 154.232 1.00 172.26 ? 79  GLU L N   1 
ATOM   3224 C CA  . GLU D 3 79  ? 101.825 124.586 154.579 1.00 172.26 ? 79  GLU L CA  1 
ATOM   3225 C C   . GLU D 3 79  ? 101.571 124.703 156.075 1.00 172.26 ? 79  GLU L C   1 
ATOM   3226 O O   . GLU D 3 79  ? 102.442 125.139 156.831 1.00 172.26 ? 79  GLU L O   1 
ATOM   3227 C CB  . GLU D 3 79  ? 102.227 123.138 154.195 1.00 172.26 ? 79  GLU L CB  1 
ATOM   3228 C CG  . GLU D 3 79  ? 101.178 122.031 154.300 1.00 172.26 ? 79  GLU L CG  1 
ATOM   3229 C CD  . GLU D 3 79  ? 99.986  122.231 153.390 1.00 172.26 ? 79  GLU L CD  1 
ATOM   3230 O OE1 . GLU D 3 79  ? 100.128 122.876 152.328 1.00 172.26 ? 79  GLU L OE1 1 
ATOM   3231 O OE2 . GLU D 3 79  ? 98.896  121.733 153.741 1.00 172.26 ? 79  GLU L OE2 1 
ATOM   3232 N N   . ASN D 3 80  ? 100.381 124.283 156.498 1.00 180.10 ? 80  ASN L N   1 
ATOM   3233 C CA  . ASN D 3 80  ? 100.120 124.034 157.906 1.00 180.10 ? 80  ASN L CA  1 
ATOM   3234 C C   . ASN D 3 80  ? 100.785 122.724 158.329 1.00 180.10 ? 80  ASN L C   1 
ATOM   3235 O O   . ASN D 3 80  ? 101.340 121.992 157.503 1.00 180.10 ? 80  ASN L O   1 
ATOM   3236 C CB  . ASN D 3 80  ? 98.618  123.987 158.164 1.00 180.10 ? 80  ASN L CB  1 
ATOM   3237 C CG  . ASN D 3 80  ? 97.948  125.320 157.926 1.00 180.10 ? 80  ASN L CG  1 
ATOM   3238 O OD1 . ASN D 3 80  ? 98.468  126.368 158.310 1.00 180.10 ? 80  ASN L OD1 1 
ATOM   3239 N ND2 . ASN D 3 80  ? 96.789  125.290 157.279 1.00 180.10 ? 80  ASN L ND2 1 
ATOM   3240 N N   . THR D 3 81  ? 100.671 122.420 159.633 1.00 181.92 ? 81  THR L N   1 
ATOM   3241 C CA  . THR D 3 81  ? 101.327 121.301 160.359 1.00 181.92 ? 81  THR L CA  1 
ATOM   3242 C C   . THR D 3 81  ? 102.759 121.035 159.874 1.00 181.92 ? 81  THR L C   1 
ATOM   3243 O O   . THR D 3 81  ? 103.181 119.901 159.628 1.00 181.92 ? 81  THR L O   1 
ATOM   3244 C CB  . THR D 3 81  ? 100.453 120.020 160.381 1.00 181.92 ? 81  THR L CB  1 
ATOM   3245 O OG1 . THR D 3 81  ? 101.099 119.013 161.173 1.00 181.92 ? 81  THR L OG1 1 
ATOM   3246 C CG2 . THR D 3 81  ? 100.075 119.428 158.996 1.00 181.92 ? 81  THR L CG2 1 
ATOM   3247 N N   . LEU D 3 82  ? 103.516 122.124 159.764 1.00 172.58 ? 82  LEU L N   1 
ATOM   3248 C CA  . LEU D 3 82  ? 104.870 122.072 159.240 1.00 172.58 ? 82  LEU L CA  1 
ATOM   3249 C C   . LEU D 3 82  ? 105.793 121.380 160.231 1.00 172.58 ? 82  LEU L C   1 
ATOM   3250 O O   . LEU D 3 82  ? 105.767 121.678 161.429 1.00 172.58 ? 82  LEU L O   1 
ATOM   3251 C CB  . LEU D 3 82  ? 105.359 123.485 158.951 1.00 172.58 ? 82  LEU L CB  1 
ATOM   3252 C CG  . LEU D 3 82  ? 106.762 123.571 158.374 1.00 172.58 ? 82  LEU L CG  1 
ATOM   3253 C CD1 . LEU D 3 82  ? 106.804 122.838 157.050 1.00 172.58 ? 82  LEU L CD1 1 
ATOM   3254 C CD2 . LEU D 3 82  ? 107.165 125.023 158.211 1.00 172.58 ? 82  LEU L CD2 1 
ATOM   3255 N N   . SER D 3 83  ? 106.609 120.456 159.730 1.00 170.57 ? 83  SER L N   1 
ATOM   3256 C CA  . SER D 3 83  ? 107.408 119.594 160.585 1.00 170.57 ? 83  SER L CA  1 
ATOM   3257 C C   . SER D 3 83  ? 108.552 120.375 161.231 1.00 170.57 ? 83  SER L C   1 
ATOM   3258 O O   . SER D 3 83  ? 108.781 121.556 160.958 1.00 170.57 ? 83  SER L O   1 
ATOM   3259 C CB  . SER D 3 83  ? 107.945 118.411 159.787 1.00 170.57 ? 83  SER L CB  1 
ATOM   3260 O OG  . SER D 3 83  ? 108.855 118.851 158.797 1.00 170.57 ? 83  SER L OG  1 
ATOM   3261 N N   . GLU D 3 84  ? 109.293 119.686 162.091 1.00 170.17 ? 84  GLU L N   1 
ATOM   3262 C CA  . GLU D 3 84  ? 110.286 120.325 162.941 1.00 170.17 ? 84  GLU L CA  1 
ATOM   3263 C C   . GLU D 3 84  ? 111.578 120.584 162.173 1.00 170.17 ? 84  GLU L C   1 
ATOM   3264 O O   . GLU D 3 84  ? 111.641 120.466 160.944 1.00 170.17 ? 84  GLU L O   1 
ATOM   3265 C CB  . GLU D 3 84  ? 110.545 119.468 164.176 1.00 170.17 ? 84  GLU L CB  1 
ATOM   3266 C CG  . GLU D 3 84  ? 109.376 119.397 165.126 1.00 170.17 ? 84  GLU L CG  1 
ATOM   3267 C CD  . GLU D 3 84  ? 109.106 120.722 165.805 1.00 170.17 ? 84  GLU L CD  1 
ATOM   3268 O OE1 . GLU D 3 84  ? 110.071 121.473 166.064 1.00 170.17 ? 84  GLU L OE1 1 
ATOM   3269 O OE2 . GLU D 3 84  ? 107.924 121.014 166.078 1.00 170.17 ? 84  GLU L OE2 1 
ATOM   3270 N N   . ASP D 3 85  ? 112.620 120.946 162.930 1.00 165.58 ? 85  ASP L N   1 
ATOM   3271 C CA  . ASP D 3 85  ? 113.982 121.210 162.457 1.00 165.58 ? 85  ASP L CA  1 
ATOM   3272 C C   . ASP D 3 85  ? 113.994 122.336 161.416 1.00 165.58 ? 85  ASP L C   1 
ATOM   3273 O O   . ASP D 3 85  ? 114.281 122.146 160.233 1.00 165.58 ? 85  ASP L O   1 
ATOM   3274 C CB  . ASP D 3 85  ? 114.638 119.922 161.939 1.00 165.58 ? 85  ASP L CB  1 
ATOM   3275 C CG  . ASP D 3 85  ? 114.913 118.917 163.053 1.00 165.58 ? 85  ASP L CG  1 
ATOM   3276 O OD1 . ASP D 3 85  ? 115.161 119.342 164.202 1.00 165.58 ? 85  ASP L OD1 1 
ATOM   3277 O OD2 . ASP D 3 85  ? 114.871 117.700 162.780 1.00 165.58 ? 85  ASP L OD2 1 
ATOM   3278 N N   . VAL D 3 86  ? 113.635 123.524 161.905 1.00 154.61 ? 86  VAL L N   1 
ATOM   3279 C CA  . VAL D 3 86  ? 113.621 124.713 161.066 1.00 154.61 ? 86  VAL L CA  1 
ATOM   3280 C C   . VAL D 3 86  ? 115.058 125.150 160.797 1.00 154.61 ? 86  VAL L C   1 
ATOM   3281 O O   . VAL D 3 86  ? 115.989 124.823 161.547 1.00 154.61 ? 86  VAL L O   1 
ATOM   3282 C CB  . VAL D 3 86  ? 112.790 125.827 161.738 1.00 154.61 ? 86  VAL L CB  1 
ATOM   3283 C CG1 . VAL D 3 86  ? 113.517 126.429 162.936 1.00 154.61 ? 86  VAL L CG1 1 
ATOM   3284 C CG2 . VAL D 3 86  ? 112.330 126.908 160.744 1.00 154.61 ? 86  VAL L CG2 1 
ATOM   3285 N N   . ALA D 3 87  ? 115.250 125.854 159.685 1.00 149.40 ? 87  ALA L N   1 
ATOM   3286 C CA  . ALA D 3 87  ? 116.533 126.422 159.316 1.00 149.40 ? 87  ALA L CA  1 
ATOM   3287 C C   . ALA D 3 87  ? 116.259 127.613 158.416 1.00 149.40 ? 87  ALA L C   1 
ATOM   3288 O O   . ALA D 3 87  ? 115.195 127.705 157.803 1.00 149.40 ? 87  ALA L O   1 
ATOM   3289 C CB  . ALA D 3 87  ? 117.416 125.391 158.618 1.00 149.40 ? 87  ALA L CB  1 
ATOM   3290 N N   . ASP D 3 88  ? 117.218 128.532 158.344 1.00 146.86 ? 88  ASP L N   1 
ATOM   3291 C CA  . ASP D 3 88  ? 116.975 129.772 157.618 1.00 146.86 ? 88  ASP L CA  1 
ATOM   3292 C C   . ASP D 3 88  ? 116.982 129.551 156.108 1.00 146.86 ? 88  ASP L C   1 
ATOM   3293 O O   . ASP D 3 88  ? 117.568 128.595 155.589 1.00 146.86 ? 88  ASP L O   1 
ATOM   3294 C CB  . ASP D 3 88  ? 117.990 130.849 158.009 1.00 146.86 ? 88  ASP L CB  1 
ATOM   3295 C CG  . ASP D 3 88  ? 119.423 130.408 157.824 1.00 146.86 ? 88  ASP L CG  1 
ATOM   3296 O OD1 . ASP D 3 88  ? 119.653 129.222 157.545 1.00 146.86 ? 88  ASP L OD1 1 
ATOM   3297 O OD2 . ASP D 3 88  ? 120.329 131.256 157.953 1.00 146.86 ? 88  ASP L OD2 1 
ATOM   3298 N N   . TYR D 3 89  ? 116.297 130.447 155.411 1.00 143.71 ? 89  TYR L N   1 
ATOM   3299 C CA  . TYR D 3 89  ? 116.078 130.348 153.980 1.00 143.71 ? 89  TYR L CA  1 
ATOM   3300 C C   . TYR D 3 89  ? 116.644 131.590 153.315 1.00 143.71 ? 89  TYR L C   1 
ATOM   3301 O O   . TYR D 3 89  ? 116.416 132.706 153.789 1.00 143.71 ? 89  TYR L O   1 
ATOM   3302 C CB  . TYR D 3 89  ? 114.589 130.216 153.678 1.00 143.71 ? 89  TYR L CB  1 
ATOM   3303 C CG  . TYR D 3 89  ? 113.977 128.940 154.197 1.00 143.71 ? 89  TYR L CG  1 
ATOM   3304 C CD1 . TYR D 3 89  ? 114.082 127.761 153.483 1.00 143.71 ? 89  TYR L CD1 1 
ATOM   3305 C CD2 . TYR D 3 89  ? 113.295 128.915 155.402 1.00 143.71 ? 89  TYR L CD2 1 
ATOM   3306 C CE1 . TYR D 3 89  ? 113.523 126.591 153.949 1.00 143.71 ? 89  TYR L CE1 1 
ATOM   3307 C CE2 . TYR D 3 89  ? 112.728 127.749 155.874 1.00 143.71 ? 89  TYR L CE2 1 
ATOM   3308 C CZ  . TYR D 3 89  ? 112.855 126.590 155.146 1.00 143.71 ? 89  TYR L CZ  1 
ATOM   3309 O OH  . TYR D 3 89  ? 112.300 125.421 155.610 1.00 143.71 ? 89  TYR L OH  1 
ATOM   3310 N N   . TYR D 3 90  ? 117.372 131.397 152.223 1.00 143.61 ? 90  TYR L N   1 
ATOM   3311 C CA  . TYR D 3 90  ? 117.988 132.499 151.503 1.00 143.61 ? 90  TYR L CA  1 
ATOM   3312 C C   . TYR D 3 90  ? 117.416 132.618 150.098 1.00 143.61 ? 90  TYR L C   1 
ATOM   3313 O O   . TYR D 3 90  ? 116.994 131.629 149.492 1.00 143.61 ? 90  TYR L O   1 
ATOM   3314 C CB  . TYR D 3 90  ? 119.501 132.330 151.423 1.00 143.61 ? 90  TYR L CB  1 
ATOM   3315 C CG  . TYR D 3 90  ? 120.191 132.430 152.752 1.00 143.61 ? 90  TYR L CG  1 
ATOM   3316 C CD1 . TYR D 3 90  ? 120.350 133.656 153.380 1.00 143.61 ? 90  TYR L CD1 1 
ATOM   3317 C CD2 . TYR D 3 90  ? 120.711 131.305 153.366 1.00 143.61 ? 90  TYR L CD2 1 
ATOM   3318 C CE1 . TYR D 3 90  ? 120.999 133.754 154.594 1.00 143.61 ? 90  TYR L CE1 1 
ATOM   3319 C CE2 . TYR D 3 90  ? 121.360 131.391 154.578 1.00 143.61 ? 90  TYR L CE2 1 
ATOM   3320 C CZ  . TYR D 3 90  ? 121.503 132.617 155.187 1.00 143.61 ? 90  TYR L CZ  1 
ATOM   3321 O OH  . TYR D 3 90  ? 122.149 132.702 156.397 1.00 143.61 ? 90  TYR L OH  1 
ATOM   3322 N N   . CYS D 3 91  ? 117.426 133.845 149.587 1.00 147.96 ? 91  CYS L N   1 
ATOM   3323 C CA  . CYS D 3 91  ? 116.880 134.191 148.284 1.00 147.96 ? 91  CYS L CA  1 
ATOM   3324 C C   . CYS D 3 91  ? 117.966 134.858 147.457 1.00 147.96 ? 91  CYS L C   1 
ATOM   3325 O O   . CYS D 3 91  ? 118.705 135.703 147.971 1.00 147.96 ? 91  CYS L O   1 
ATOM   3326 C CB  . CYS D 3 91  ? 115.680 135.142 148.440 1.00 147.96 ? 91  CYS L CB  1 
ATOM   3327 S SG  . CYS D 3 91  ? 114.820 135.608 146.919 1.00 147.96 ? 91  CYS L SG  1 
ATOM   3328 N N   . LEU D 3 92  ? 118.073 134.479 146.182 1.00 142.64 ? 92  LEU L N   1 
ATOM   3329 C CA  . LEU D 3 92  ? 118.918 135.246 145.265 1.00 142.64 ? 92  LEU L CA  1 
ATOM   3330 C C   . LEU D 3 92  ? 118.336 135.168 143.858 1.00 142.64 ? 92  LEU L C   1 
ATOM   3331 O O   . LEU D 3 92  ? 117.239 134.650 143.649 1.00 142.64 ? 92  LEU L O   1 
ATOM   3332 C CB  . LEU D 3 92  ? 120.395 134.813 145.336 1.00 142.64 ? 92  LEU L CB  1 
ATOM   3333 C CG  . LEU D 3 92  ? 121.018 133.443 145.066 1.00 142.64 ? 92  LEU L CG  1 
ATOM   3334 C CD1 . LEU D 3 92  ? 121.348 133.264 143.596 1.00 142.64 ? 92  LEU L CD1 1 
ATOM   3335 C CD2 . LEU D 3 92  ? 122.266 133.260 145.921 1.00 142.64 ? 92  LEU L CD2 1 
ATOM   3336 N N   . GLN D 3 93  ? 119.063 135.716 142.891 1.00 141.59 ? 93  GLN L N   1 
ATOM   3337 C CA  . GLN D 3 93  ? 118.528 135.931 141.555 1.00 141.59 ? 93  GLN L CA  1 
ATOM   3338 C C   . GLN D 3 93  ? 119.506 135.442 140.500 1.00 141.59 ? 93  GLN L C   1 
ATOM   3339 O O   . GLN D 3 93  ? 120.620 135.013 140.802 1.00 141.59 ? 93  GLN L O   1 
ATOM   3340 C CB  . GLN D 3 93  ? 118.217 137.412 141.329 1.00 141.59 ? 93  GLN L CB  1 
ATOM   3341 C CG  . GLN D 3 93  ? 119.445 138.291 141.181 1.00 141.59 ? 93  GLN L CG  1 
ATOM   3342 C CD  . GLN D 3 93  ? 120.003 138.773 142.506 1.00 141.59 ? 93  GLN L CD  1 
ATOM   3343 O OE1 . GLN D 3 93  ? 119.734 138.198 143.561 1.00 141.59 ? 93  GLN L OE1 1 
ATOM   3344 N NE2 . GLN D 3 93  ? 120.769 139.853 142.459 1.00 141.59 ? 93  GLN L NE2 1 
ATOM   3345 N N   . SER D 3 94  ? 119.077 135.521 139.240 1.00 138.66 ? 94  SER L N   1 
ATOM   3346 C CA  . SER D 3 94  ? 119.867 135.020 138.127 1.00 138.66 ? 94  SER L CA  1 
ATOM   3347 C C   . SER D 3 94  ? 120.075 136.050 137.026 1.00 138.66 ? 94  SER L C   1 
ATOM   3348 O O   . SER D 3 94  ? 120.393 135.672 135.898 1.00 138.66 ? 94  SER L O   1 
ATOM   3349 C CB  . SER D 3 94  ? 119.215 133.777 137.534 1.00 138.66 ? 94  SER L CB  1 
ATOM   3350 O OG  . SER D 3 94  ? 118.046 134.136 136.834 1.00 138.66 ? 94  SER L OG  1 
ATOM   3351 N N   . ASP D 3 95  ? 119.906 137.330 137.318 1.00 140.53 ? 95  ASP L N   1 
ATOM   3352 C CA  . ASP D 3 95  ? 120.339 138.392 136.426 1.00 140.53 ? 95  ASP L CA  1 
ATOM   3353 C C   . ASP D 3 95  ? 121.468 139.141 137.109 1.00 140.53 ? 95  ASP L C   1 
ATOM   3354 O O   . ASP D 3 95  ? 121.751 138.901 138.286 1.00 140.53 ? 95  ASP L O   1 
ATOM   3355 C CB  . ASP D 3 95  ? 119.199 139.363 136.101 1.00 140.53 ? 95  ASP L CB  1 
ATOM   3356 C CG  . ASP D 3 95  ? 118.100 138.719 135.302 1.00 140.53 ? 95  ASP L CG  1 
ATOM   3357 O OD1 . ASP D 3 95  ? 118.384 137.727 134.618 1.00 140.53 ? 95  ASP L OD1 1 
ATOM   3358 O OD2 . ASP D 3 95  ? 116.957 139.213 135.335 1.00 140.53 ? 95  ASP L OD2 1 
ATOM   3359 N N   . ASN D 3 96  ? 122.094 140.055 136.354 1.00 148.77 ? 96  ASN L N   1 
ATOM   3360 C CA  . ASN D 3 96  ? 122.960 141.103 136.906 1.00 148.77 ? 96  ASN L CA  1 
ATOM   3361 C C   . ASN D 3 96  ? 124.148 140.511 137.666 1.00 148.77 ? 96  ASN L C   1 
ATOM   3362 O O   . ASN D 3 96  ? 124.162 140.462 138.895 1.00 148.77 ? 96  ASN L O   1 
ATOM   3363 C CB  . ASN D 3 96  ? 122.156 142.067 137.782 1.00 148.77 ? 96  ASN L CB  1 
ATOM   3364 C CG  . ASN D 3 96  ? 121.145 142.860 136.985 1.00 148.77 ? 96  ASN L CG  1 
ATOM   3365 O OD1 . ASN D 3 96  ? 121.421 143.289 135.864 1.00 148.77 ? 96  ASN L OD1 1 
ATOM   3366 N ND2 . ASN D 3 96  ? 119.964 143.061 137.559 1.00 148.77 ? 96  ASN L ND2 1 
ATOM   3367 N N   . MET D 3 97  ? 125.117 140.023 136.892 1.00 145.92 ? 97  MET L N   1 
ATOM   3368 C CA  . MET D 3 97  ? 126.155 139.019 137.127 1.00 145.92 ? 97  MET L CA  1 
ATOM   3369 C C   . MET D 3 97  ? 126.731 138.851 138.539 1.00 145.92 ? 97  MET L C   1 
ATOM   3370 O O   . MET D 3 97  ? 127.044 137.706 138.889 1.00 145.92 ? 97  MET L O   1 
ATOM   3371 C CB  . MET D 3 97  ? 127.294 139.271 136.135 1.00 145.92 ? 97  MET L CB  1 
ATOM   3372 C CG  . MET D 3 97  ? 126.910 139.089 134.680 1.00 145.92 ? 97  MET L CG  1 
ATOM   3373 S SD  . MET D 3 97  ? 126.320 137.432 134.291 1.00 145.92 ? 97  MET L SD  1 
ATOM   3374 C CE  . MET D 3 97  ? 124.565 137.731 134.063 1.00 145.92 ? 97  MET L CE  1 
ATOM   3375 N N   . PRO D 3 98  ? 126.969 139.897 139.356 1.00 147.87 ? 98  PRO L N   1 
ATOM   3376 C CA  . PRO D 3 98  ? 127.239 139.613 140.783 1.00 147.87 ? 98  PRO L CA  1 
ATOM   3377 C C   . PRO D 3 98  ? 126.112 138.871 141.495 1.00 147.87 ? 98  PRO L C   1 
ATOM   3378 O O   . PRO D 3 98  ? 126.388 138.025 142.355 1.00 147.87 ? 98  PRO L O   1 
ATOM   3379 C CB  . PRO D 3 98  ? 127.473 141.006 141.376 1.00 147.87 ? 98  PRO L CB  1 
ATOM   3380 C CG  . PRO D 3 98  ? 127.984 141.793 140.260 1.00 147.87 ? 98  PRO L CG  1 
ATOM   3381 C CD  . PRO D 3 98  ? 127.258 141.316 139.052 1.00 147.87 ? 98  PRO L CD  1 
ATOM   3382 N N   . LEU D 3 99  ? 124.854 139.190 141.180 1.00 144.93 ? 99  LEU L N   1 
ATOM   3383 C CA  . LEU D 3 99  ? 123.647 138.375 141.425 1.00 144.93 ? 99  LEU L CA  1 
ATOM   3384 C C   . LEU D 3 99  ? 123.411 138.000 142.897 1.00 144.93 ? 99  LEU L C   1 
ATOM   3385 O O   . LEU D 3 99  ? 122.613 137.114 143.205 1.00 144.93 ? 99  LEU L O   1 
ATOM   3386 C CB  . LEU D 3 99  ? 123.635 137.122 140.530 1.00 144.93 ? 99  LEU L CB  1 
ATOM   3387 C CG  . LEU D 3 99  ? 124.617 135.938 140.489 1.00 144.93 ? 99  LEU L CG  1 
ATOM   3388 C CD1 . LEU D 3 99  ? 124.286 134.860 141.496 1.00 144.93 ? 99  LEU L CD1 1 
ATOM   3389 C CD2 . LEU D 3 99  ? 124.697 135.343 139.094 1.00 144.93 ? 99  LEU L CD2 1 
ATOM   3390 N N   . THR D 3 100 ? 124.064 138.734 143.800 1.00 141.61 ? 100 THR L N   1 
ATOM   3391 C CA  . THR D 3 100 ? 123.987 138.559 145.264 1.00 141.61 ? 100 THR L CA  1 
ATOM   3392 C C   . THR D 3 100 ? 124.193 137.128 145.761 1.00 141.61 ? 100 THR L C   1 
ATOM   3393 O O   . THR D 3 100 ? 123.385 136.609 146.535 1.00 141.61 ? 100 THR L O   1 
ATOM   3394 C CB  . THR D 3 100 ? 122.641 139.054 145.832 1.00 141.61 ? 100 THR L CB  1 
ATOM   3395 O OG1 . THR D 3 100 ? 121.577 138.219 145.364 1.00 141.61 ? 100 THR L OG1 1 
ATOM   3396 C CG2 . THR D 3 100 ? 122.382 140.478 145.396 1.00 141.61 ? 100 THR L CG2 1 
# 
