data_8W4Y
# 
_entry.id   8W4Y 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8W4Y         pdb_00008w4y 10.2210/pdb8w4y/pdb 
WWPDB D_1300040396 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-03-12 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8W4Y 
_pdbx_database_status.recvd_initial_deposition_date   2023-08-25 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              aquarius@mail.ecc.u-tokyo.ac.jp 
_pdbx_contact_author.name_first         Kiyohiko 
_pdbx_contact_author.name_last          Igarashi 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-5152-7177 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Tachioka, M.'    1  0000-0002-3558-8700 
'Yamaguchi, S.'   2  ?                   
'Nakamura, A.'    3  ?                   
'Ishida, T.'      4  ?                   
'Kusaka, K.'      5  ?                   
'Yamada, T.'      6  ?                   
'Yano, N.'        7  ?                   
'Chatake, T.'     8  ?                   
'Tamada, T.'      9  ?                   
'Takeda, K.'      10 ?                   
'Niwa, S.'        11 ?                   
'Tanaka, H.'      12 ?                   
'Takahashi, S.'   13 ?                   
'Inaka, K.'       14 ?                   
'Furubayashi, N.' 15 ?                   
'Deguchi, S.'     16 ?                   
'Samejima, M.'    17 ?                   
'Igarashi, K.'    18 ?                   
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     
'Deprotonated Arginine Controls a Putative Catalytic Base in Invert-ing Family 6 Glycoside Hydrolase' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Tachioka, M.'    1  0000-0002-3558-8700 
primary 'Yamaguchi, S.'   2  ?                   
primary 'Nakamura, A.'    3  ?                   
primary 'Ishida, T.'      4  ?                   
primary 'Kusaka, K.'      5  ?                   
primary 'Yamada, T.'      6  ?                   
primary 'Yano, N.'        7  ?                   
primary 'Chatake, T.'     8  ?                   
primary 'Tamada, T.'      9  ?                   
primary 'Takeda, K.'      10 ?                   
primary 'Niwa, S.'        11 ?                   
primary 'Tanaka, H.'      12 ?                   
primary 'Takahashi, S.'   13 ?                   
primary 'Inaka, K.'       14 ?                   
primary 'Furubayashi, N.' 15 ?                   
primary 'Deguchi, S.'     16 ?                   
primary 'Samejima, M.'    17 ?                   
primary 'Igarashi, K.'    18 0000-0001-5152-7177 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man Glucanase 38381.574 1   ? ? ? ? 
2 water   nat water     18.015    246 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;SANNPWTGFQIFLSPYYANEVAAAAKQITDPTLSSKAASVANIPTFTWLDSVAKIPDLGTYLASASALGKSTGTKQLVQI
VIYDLPDRDCAAKASNGEFSIANNGQANYENYIDQIVAQIQQFPDVRVVAVIEPDSLANLVTNLNVQKCANAKTTYLACV
NYALTNLAKVGVYMYMDAGHAGWLGWPANLSPAAQLFTQVWQNAGKSPFIKGLATNVANYNALQAASPDPITQGNPNYDE
IHYINALAPLLQQAGWDATFIVDQGRSGVQNIRQQWGDWCNIKGAGFGTRPTTNTGSQFIDSIVWVKPGGECDGTSNSSS
PRYDSTCSLPDAAQPAPEAGTWFQAYFQTLVSAANPPL
;
_entity_poly.pdbx_seq_one_letter_code_can   
;SANNPWTGFQIFLSPYYANEVAAAAKQITDPTLSSKAASVANIPTFTWLDSVAKIPDLGTYLASASALGKSTGTKQLVQI
VIYDLPDRDCAAKASNGEFSIANNGQANYENYIDQIVAQIQQFPDVRVVAVIEPDSLANLVTNLNVQKCANAKTTYLACV
NYALTNLAKVGVYMYMDAGHAGWLGWPANLSPAAQLFTQVWQNAGKSPFIKGLATNVANYNALQAASPDPITQGNPNYDE
IHYINALAPLLQQAGWDATFIVDQGRSGVQNIRQQWGDWCNIKGAGFGTRPTTNTGSQFIDSIVWVKPGGECDGTSNSSS
PRYDSTCSLPDAAQPAPEAGTWFQAYFQTLVSAANPPL
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   2 
_pdbx_entity_nonpoly.name        water 
_pdbx_entity_nonpoly.comp_id     HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   SER n 
1 2   ALA n 
1 3   ASN n 
1 4   ASN n 
1 5   PRO n 
1 6   TRP n 
1 7   THR n 
1 8   GLY n 
1 9   PHE n 
1 10  GLN n 
1 11  ILE n 
1 12  PHE n 
1 13  LEU n 
1 14  SER n 
1 15  PRO n 
1 16  TYR n 
1 17  TYR n 
1 18  ALA n 
1 19  ASN n 
1 20  GLU n 
1 21  VAL n 
1 22  ALA n 
1 23  ALA n 
1 24  ALA n 
1 25  ALA n 
1 26  LYS n 
1 27  GLN n 
1 28  ILE n 
1 29  THR n 
1 30  ASP n 
1 31  PRO n 
1 32  THR n 
1 33  LEU n 
1 34  SER n 
1 35  SER n 
1 36  LYS n 
1 37  ALA n 
1 38  ALA n 
1 39  SER n 
1 40  VAL n 
1 41  ALA n 
1 42  ASN n 
1 43  ILE n 
1 44  PRO n 
1 45  THR n 
1 46  PHE n 
1 47  THR n 
1 48  TRP n 
1 49  LEU n 
1 50  ASP n 
1 51  SER n 
1 52  VAL n 
1 53  ALA n 
1 54  LYS n 
1 55  ILE n 
1 56  PRO n 
1 57  ASP n 
1 58  LEU n 
1 59  GLY n 
1 60  THR n 
1 61  TYR n 
1 62  LEU n 
1 63  ALA n 
1 64  SER n 
1 65  ALA n 
1 66  SER n 
1 67  ALA n 
1 68  LEU n 
1 69  GLY n 
1 70  LYS n 
1 71  SER n 
1 72  THR n 
1 73  GLY n 
1 74  THR n 
1 75  LYS n 
1 76  GLN n 
1 77  LEU n 
1 78  VAL n 
1 79  GLN n 
1 80  ILE n 
1 81  VAL n 
1 82  ILE n 
1 83  TYR n 
1 84  ASP n 
1 85  LEU n 
1 86  PRO n 
1 87  ASP n 
1 88  ARG n 
1 89  ASP n 
1 90  CYS n 
1 91  ALA n 
1 92  ALA n 
1 93  LYS n 
1 94  ALA n 
1 95  SER n 
1 96  ASN n 
1 97  GLY n 
1 98  GLU n 
1 99  PHE n 
1 100 SER n 
1 101 ILE n 
1 102 ALA n 
1 103 ASN n 
1 104 ASN n 
1 105 GLY n 
1 106 GLN n 
1 107 ALA n 
1 108 ASN n 
1 109 TYR n 
1 110 GLU n 
1 111 ASN n 
1 112 TYR n 
1 113 ILE n 
1 114 ASP n 
1 115 GLN n 
1 116 ILE n 
1 117 VAL n 
1 118 ALA n 
1 119 GLN n 
1 120 ILE n 
1 121 GLN n 
1 122 GLN n 
1 123 PHE n 
1 124 PRO n 
1 125 ASP n 
1 126 VAL n 
1 127 ARG n 
1 128 VAL n 
1 129 VAL n 
1 130 ALA n 
1 131 VAL n 
1 132 ILE n 
1 133 GLU n 
1 134 PRO n 
1 135 ASP n 
1 136 SER n 
1 137 LEU n 
1 138 ALA n 
1 139 ASN n 
1 140 LEU n 
1 141 VAL n 
1 142 THR n 
1 143 ASN n 
1 144 LEU n 
1 145 ASN n 
1 146 VAL n 
1 147 GLN n 
1 148 LYS n 
1 149 CYS n 
1 150 ALA n 
1 151 ASN n 
1 152 ALA n 
1 153 LYS n 
1 154 THR n 
1 155 THR n 
1 156 TYR n 
1 157 LEU n 
1 158 ALA n 
1 159 CYS n 
1 160 VAL n 
1 161 ASN n 
1 162 TYR n 
1 163 ALA n 
1 164 LEU n 
1 165 THR n 
1 166 ASN n 
1 167 LEU n 
1 168 ALA n 
1 169 LYS n 
1 170 VAL n 
1 171 GLY n 
1 172 VAL n 
1 173 TYR n 
1 174 MET n 
1 175 TYR n 
1 176 MET n 
1 177 ASP n 
1 178 ALA n 
1 179 GLY n 
1 180 HIS n 
1 181 ALA n 
1 182 GLY n 
1 183 TRP n 
1 184 LEU n 
1 185 GLY n 
1 186 TRP n 
1 187 PRO n 
1 188 ALA n 
1 189 ASN n 
1 190 LEU n 
1 191 SER n 
1 192 PRO n 
1 193 ALA n 
1 194 ALA n 
1 195 GLN n 
1 196 LEU n 
1 197 PHE n 
1 198 THR n 
1 199 GLN n 
1 200 VAL n 
1 201 TRP n 
1 202 GLN n 
1 203 ASN n 
1 204 ALA n 
1 205 GLY n 
1 206 LYS n 
1 207 SER n 
1 208 PRO n 
1 209 PHE n 
1 210 ILE n 
1 211 LYS n 
1 212 GLY n 
1 213 LEU n 
1 214 ALA n 
1 215 THR n 
1 216 ASN n 
1 217 VAL n 
1 218 ALA n 
1 219 ASN n 
1 220 TYR n 
1 221 ASN n 
1 222 ALA n 
1 223 LEU n 
1 224 GLN n 
1 225 ALA n 
1 226 ALA n 
1 227 SER n 
1 228 PRO n 
1 229 ASP n 
1 230 PRO n 
1 231 ILE n 
1 232 THR n 
1 233 GLN n 
1 234 GLY n 
1 235 ASN n 
1 236 PRO n 
1 237 ASN n 
1 238 TYR n 
1 239 ASP n 
1 240 GLU n 
1 241 ILE n 
1 242 HIS n 
1 243 TYR n 
1 244 ILE n 
1 245 ASN n 
1 246 ALA n 
1 247 LEU n 
1 248 ALA n 
1 249 PRO n 
1 250 LEU n 
1 251 LEU n 
1 252 GLN n 
1 253 GLN n 
1 254 ALA n 
1 255 GLY n 
1 256 TRP n 
1 257 ASP n 
1 258 ALA n 
1 259 THR n 
1 260 PHE n 
1 261 ILE n 
1 262 VAL n 
1 263 ASP n 
1 264 GLN n 
1 265 GLY n 
1 266 ARG n 
1 267 SER n 
1 268 GLY n 
1 269 VAL n 
1 270 GLN n 
1 271 ASN n 
1 272 ILE n 
1 273 ARG n 
1 274 GLN n 
1 275 GLN n 
1 276 TRP n 
1 277 GLY n 
1 278 ASP n 
1 279 TRP n 
1 280 CYS n 
1 281 ASN n 
1 282 ILE n 
1 283 LYS n 
1 284 GLY n 
1 285 ALA n 
1 286 GLY n 
1 287 PHE n 
1 288 GLY n 
1 289 THR n 
1 290 ARG n 
1 291 PRO n 
1 292 THR n 
1 293 THR n 
1 294 ASN n 
1 295 THR n 
1 296 GLY n 
1 297 SER n 
1 298 GLN n 
1 299 PHE n 
1 300 ILE n 
1 301 ASP n 
1 302 SER n 
1 303 ILE n 
1 304 VAL n 
1 305 TRP n 
1 306 VAL n 
1 307 LYS n 
1 308 PRO n 
1 309 GLY n 
1 310 GLY n 
1 311 GLU n 
1 312 CYS n 
1 313 ASP n 
1 314 GLY n 
1 315 THR n 
1 316 SER n 
1 317 ASN n 
1 318 SER n 
1 319 SER n 
1 320 SER n 
1 321 PRO n 
1 322 ARG n 
1 323 TYR n 
1 324 ASP n 
1 325 SER n 
1 326 THR n 
1 327 CYS n 
1 328 SER n 
1 329 LEU n 
1 330 PRO n 
1 331 ASP n 
1 332 ALA n 
1 333 ALA n 
1 334 GLN n 
1 335 PRO n 
1 336 ALA n 
1 337 PRO n 
1 338 GLU n 
1 339 ALA n 
1 340 GLY n 
1 341 THR n 
1 342 TRP n 
1 343 PHE n 
1 344 GLN n 
1 345 ALA n 
1 346 TYR n 
1 347 PHE n 
1 348 GLN n 
1 349 THR n 
1 350 LEU n 
1 351 VAL n 
1 352 SER n 
1 353 ALA n 
1 354 ALA n 
1 355 ASN n 
1 356 PRO n 
1 357 PRO n 
1 358 LEU n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   358 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 cel6A 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Phanerodontia chrysosporium' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     2822231 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Komagataella pastoris' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     4922 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER           ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   SER 1   82  82  SER SER A . n 
A 1 2   ALA 2   83  83  ALA ALA A . n 
A 1 3   ASN 3   84  84  ASN ASN A . n 
A 1 4   ASN 4   85  85  ASN ASN A . n 
A 1 5   PRO 5   86  86  PRO PRO A . n 
A 1 6   TRP 6   87  87  TRP TRP A . n 
A 1 7   THR 7   88  88  THR THR A . n 
A 1 8   GLY 8   89  89  GLY GLY A . n 
A 1 9   PHE 9   90  90  PHE PHE A . n 
A 1 10  GLN 10  91  91  GLN GLN A . n 
A 1 11  ILE 11  92  92  ILE ILE A . n 
A 1 12  PHE 12  93  93  PHE PHE A . n 
A 1 13  LEU 13  94  94  LEU LEU A . n 
A 1 14  SER 14  95  95  SER SER A . n 
A 1 15  PRO 15  96  96  PRO PRO A . n 
A 1 16  TYR 16  97  97  TYR TYR A . n 
A 1 17  TYR 17  98  98  TYR TYR A . n 
A 1 18  ALA 18  99  99  ALA ALA A . n 
A 1 19  ASN 19  100 100 ASN ASN A . n 
A 1 20  GLU 20  101 101 GLU GLU A . n 
A 1 21  VAL 21  102 102 VAL VAL A . n 
A 1 22  ALA 22  103 103 ALA ALA A . n 
A 1 23  ALA 23  104 104 ALA ALA A . n 
A 1 24  ALA 24  105 105 ALA ALA A . n 
A 1 25  ALA 25  106 106 ALA ALA A . n 
A 1 26  LYS 26  107 107 LYS LYS A . n 
A 1 27  GLN 27  108 108 GLN GLN A . n 
A 1 28  ILE 28  109 109 ILE ILE A . n 
A 1 29  THR 29  110 110 THR THR A . n 
A 1 30  ASP 30  111 111 ASP ASP A . n 
A 1 31  PRO 31  112 112 PRO PRO A . n 
A 1 32  THR 32  113 113 THR THR A . n 
A 1 33  LEU 33  114 114 LEU LEU A . n 
A 1 34  SER 34  115 115 SER SER A . n 
A 1 35  SER 35  116 116 SER SER A . n 
A 1 36  LYS 36  117 117 LYS LYS A . n 
A 1 37  ALA 37  118 118 ALA ALA A . n 
A 1 38  ALA 38  119 119 ALA ALA A . n 
A 1 39  SER 39  120 120 SER SER A . n 
A 1 40  VAL 40  121 121 VAL VAL A . n 
A 1 41  ALA 41  122 122 ALA ALA A . n 
A 1 42  ASN 42  123 123 ASN ASN A . n 
A 1 43  ILE 43  124 124 ILE ILE A . n 
A 1 44  PRO 44  125 125 PRO PRO A . n 
A 1 45  THR 45  126 126 THR THR A . n 
A 1 46  PHE 46  127 127 PHE PHE A . n 
A 1 47  THR 47  128 128 THR THR A . n 
A 1 48  TRP 48  129 129 TRP TRP A . n 
A 1 49  LEU 49  130 130 LEU LEU A . n 
A 1 50  ASP 50  131 131 ASP ASP A . n 
A 1 51  SER 51  132 132 SER SER A . n 
A 1 52  VAL 52  133 133 VAL VAL A . n 
A 1 53  ALA 53  134 134 ALA ALA A . n 
A 1 54  LYS 54  135 135 LYS LYS A . n 
A 1 55  ILE 55  136 136 ILE ILE A . n 
A 1 56  PRO 56  137 137 PRO PRO A . n 
A 1 57  ASP 57  138 138 ASP ASP A . n 
A 1 58  LEU 58  139 139 LEU LEU A . n 
A 1 59  GLY 59  140 140 GLY GLY A . n 
A 1 60  THR 60  141 141 THR THR A . n 
A 1 61  TYR 61  142 142 TYR TYR A . n 
A 1 62  LEU 62  143 143 LEU LEU A . n 
A 1 63  ALA 63  144 144 ALA ALA A . n 
A 1 64  SER 64  145 145 SER SER A . n 
A 1 65  ALA 65  146 146 ALA ALA A . n 
A 1 66  SER 66  147 147 SER SER A . n 
A 1 67  ALA 67  148 148 ALA ALA A . n 
A 1 68  LEU 68  149 149 LEU LEU A . n 
A 1 69  GLY 69  150 150 GLY GLY A . n 
A 1 70  LYS 70  151 151 LYS LYS A . n 
A 1 71  SER 71  152 152 SER SER A . n 
A 1 72  THR 72  153 153 THR THR A . n 
A 1 73  GLY 73  154 154 GLY GLY A . n 
A 1 74  THR 74  155 155 THR THR A . n 
A 1 75  LYS 75  156 156 LYS LYS A . n 
A 1 76  GLN 76  157 157 GLN GLN A . n 
A 1 77  LEU 77  158 158 LEU LEU A . n 
A 1 78  VAL 78  159 159 VAL VAL A . n 
A 1 79  GLN 79  160 160 GLN GLN A . n 
A 1 80  ILE 80  161 161 ILE ILE A . n 
A 1 81  VAL 81  162 162 VAL VAL A . n 
A 1 82  ILE 82  163 163 ILE ILE A . n 
A 1 83  TYR 83  164 164 TYR TYR A . n 
A 1 84  ASP 84  165 165 ASP ASP A . n 
A 1 85  LEU 85  166 166 LEU LEU A . n 
A 1 86  PRO 86  167 167 PRO PRO A . n 
A 1 87  ASP 87  168 168 ASP ASP A . n 
A 1 88  ARG 88  169 169 ARG ARG A . n 
A 1 89  ASP 89  170 170 ASP ASP A . n 
A 1 90  CYS 90  171 171 CYS CYS A . n 
A 1 91  ALA 91  172 172 ALA ALA A . n 
A 1 92  ALA 92  173 173 ALA ALA A . n 
A 1 93  LYS 93  174 174 LYS LYS A . n 
A 1 94  ALA 94  175 175 ALA ALA A . n 
A 1 95  SER 95  176 176 SER SER A . n 
A 1 96  ASN 96  177 177 ASN ASN A . n 
A 1 97  GLY 97  178 178 GLY GLY A . n 
A 1 98  GLU 98  179 179 GLU GLU A . n 
A 1 99  PHE 99  180 180 PHE PHE A . n 
A 1 100 SER 100 181 181 SER SER A . n 
A 1 101 ILE 101 182 182 ILE ILE A . n 
A 1 102 ALA 102 183 183 ALA ALA A . n 
A 1 103 ASN 103 184 184 ASN ASN A . n 
A 1 104 ASN 104 185 185 ASN ASN A . n 
A 1 105 GLY 105 186 186 GLY GLY A . n 
A 1 106 GLN 106 187 187 GLN GLN A . n 
A 1 107 ALA 107 188 188 ALA ALA A . n 
A 1 108 ASN 108 189 189 ASN ASN A . n 
A 1 109 TYR 109 190 190 TYR TYR A . n 
A 1 110 GLU 110 191 191 GLU GLU A . n 
A 1 111 ASN 111 192 192 ASN ASN A . n 
A 1 112 TYR 112 193 193 TYR TYR A . n 
A 1 113 ILE 113 194 194 ILE ILE A . n 
A 1 114 ASP 114 195 195 ASP ASP A . n 
A 1 115 GLN 115 196 196 GLN GLN A . n 
A 1 116 ILE 116 197 197 ILE ILE A . n 
A 1 117 VAL 117 198 198 VAL VAL A . n 
A 1 118 ALA 118 199 199 ALA ALA A . n 
A 1 119 GLN 119 200 200 GLN GLN A . n 
A 1 120 ILE 120 201 201 ILE ILE A . n 
A 1 121 GLN 121 202 202 GLN GLN A . n 
A 1 122 GLN 122 203 203 GLN GLN A . n 
A 1 123 PHE 123 204 204 PHE PHE A . n 
A 1 124 PRO 124 205 205 PRO PRO A . n 
A 1 125 ASP 125 206 206 ASP ASP A . n 
A 1 126 VAL 126 207 207 VAL VAL A . n 
A 1 127 ARG 127 208 208 ARG ARG A . n 
A 1 128 VAL 128 209 209 VAL VAL A . n 
A 1 129 VAL 129 210 210 VAL VAL A . n 
A 1 130 ALA 130 211 211 ALA ALA A . n 
A 1 131 VAL 131 212 212 VAL VAL A . n 
A 1 132 ILE 132 213 213 ILE ILE A . n 
A 1 133 GLU 133 214 214 GLU GLU A . n 
A 1 134 PRO 134 215 215 PRO PRO A . n 
A 1 135 ASP 135 216 216 ASP ASP A . n 
A 1 136 SER 136 217 217 SER SER A . n 
A 1 137 LEU 137 218 218 LEU LEU A . n 
A 1 138 ALA 138 219 219 ALA ALA A . n 
A 1 139 ASN 139 220 220 ASN ASN A . n 
A 1 140 LEU 140 221 221 LEU LEU A . n 
A 1 141 VAL 141 222 222 VAL VAL A . n 
A 1 142 THR 142 223 223 THR THR A . n 
A 1 143 ASN 143 224 224 ASN ASN A . n 
A 1 144 LEU 144 225 225 LEU LEU A . n 
A 1 145 ASN 145 226 226 ASN ASN A . n 
A 1 146 VAL 146 227 227 VAL VAL A . n 
A 1 147 GLN 147 228 228 GLN GLN A . n 
A 1 148 LYS 148 229 229 LYS LYS A . n 
A 1 149 CYS 149 230 230 CYS CYS A . n 
A 1 150 ALA 150 231 231 ALA ALA A . n 
A 1 151 ASN 151 232 232 ASN ASN A . n 
A 1 152 ALA 152 233 233 ALA ALA A . n 
A 1 153 LYS 153 234 234 LYS LYS A . n 
A 1 154 THR 154 235 235 THR THR A . n 
A 1 155 THR 155 236 236 THR THR A . n 
A 1 156 TYR 156 237 237 TYR TYR A . n 
A 1 157 LEU 157 238 238 LEU LEU A . n 
A 1 158 ALA 158 239 239 ALA ALA A . n 
A 1 159 CYS 159 240 240 CYS CYS A . n 
A 1 160 VAL 160 241 241 VAL VAL A . n 
A 1 161 ASN 161 242 242 ASN ASN A . n 
A 1 162 TYR 162 243 243 TYR TYR A . n 
A 1 163 ALA 163 244 244 ALA ALA A . n 
A 1 164 LEU 164 245 245 LEU LEU A . n 
A 1 165 THR 165 246 246 THR THR A . n 
A 1 166 ASN 166 247 247 ASN ASN A . n 
A 1 167 LEU 167 248 248 LEU LEU A . n 
A 1 168 ALA 168 249 249 ALA ALA A . n 
A 1 169 LYS 169 250 250 LYS LYS A . n 
A 1 170 VAL 170 251 251 VAL VAL A . n 
A 1 171 GLY 171 252 252 GLY GLY A . n 
A 1 172 VAL 172 253 253 VAL VAL A . n 
A 1 173 TYR 173 254 254 TYR TYR A . n 
A 1 174 MET 174 255 255 MET MET A . n 
A 1 175 TYR 175 256 256 TYR TYR A . n 
A 1 176 MET 176 257 257 MET MET A . n 
A 1 177 ASP 177 258 258 ASP ASP A . n 
A 1 178 ALA 178 259 259 ALA ALA A . n 
A 1 179 GLY 179 260 260 GLY GLY A . n 
A 1 180 HIS 180 261 261 HIS HIS A . n 
A 1 181 ALA 181 262 262 ALA ALA A . n 
A 1 182 GLY 182 263 263 GLY GLY A . n 
A 1 183 TRP 183 264 264 TRP TRP A . n 
A 1 184 LEU 184 265 265 LEU LEU A . n 
A 1 185 GLY 185 266 266 GLY GLY A . n 
A 1 186 TRP 186 267 267 TRP TRP A . n 
A 1 187 PRO 187 268 268 PRO PRO A . n 
A 1 188 ALA 188 269 269 ALA ALA A . n 
A 1 189 ASN 189 270 270 ASN ASN A . n 
A 1 190 LEU 190 271 271 LEU LEU A . n 
A 1 191 SER 191 272 272 SER SER A . n 
A 1 192 PRO 192 273 273 PRO PRO A . n 
A 1 193 ALA 193 274 274 ALA ALA A . n 
A 1 194 ALA 194 275 275 ALA ALA A . n 
A 1 195 GLN 195 276 276 GLN GLN A . n 
A 1 196 LEU 196 277 277 LEU LEU A . n 
A 1 197 PHE 197 278 278 PHE PHE A . n 
A 1 198 THR 198 279 279 THR THR A . n 
A 1 199 GLN 199 280 280 GLN GLN A . n 
A 1 200 VAL 200 281 281 VAL VAL A . n 
A 1 201 TRP 201 282 282 TRP TRP A . n 
A 1 202 GLN 202 283 283 GLN GLN A . n 
A 1 203 ASN 203 284 284 ASN ASN A . n 
A 1 204 ALA 204 285 285 ALA ALA A . n 
A 1 205 GLY 205 286 286 GLY GLY A . n 
A 1 206 LYS 206 287 287 LYS LYS A . n 
A 1 207 SER 207 288 288 SER SER A . n 
A 1 208 PRO 208 289 289 PRO PRO A . n 
A 1 209 PHE 209 290 290 PHE PHE A . n 
A 1 210 ILE 210 291 291 ILE ILE A . n 
A 1 211 LYS 211 292 292 LYS LYS A . n 
A 1 212 GLY 212 293 293 GLY GLY A . n 
A 1 213 LEU 213 294 294 LEU LEU A . n 
A 1 214 ALA 214 295 295 ALA ALA A . n 
A 1 215 THR 215 296 296 THR THR A . n 
A 1 216 ASN 216 297 297 ASN ASN A . n 
A 1 217 VAL 217 298 298 VAL VAL A . n 
A 1 218 ALA 218 299 299 ALA ALA A . n 
A 1 219 ASN 219 300 300 ASN ASN A . n 
A 1 220 TYR 220 301 301 TYR TYR A . n 
A 1 221 ASN 221 302 302 ASN ASN A . n 
A 1 222 ALA 222 303 303 ALA ALA A . n 
A 1 223 LEU 223 304 304 LEU LEU A . n 
A 1 224 GLN 224 305 305 GLN GLN A . n 
A 1 225 ALA 225 306 306 ALA ALA A . n 
A 1 226 ALA 226 307 307 ALA ALA A . n 
A 1 227 SER 227 308 308 SER SER A . n 
A 1 228 PRO 228 309 309 PRO PRO A . n 
A 1 229 ASP 229 310 310 ASP ASP A . n 
A 1 230 PRO 230 311 311 PRO PRO A . n 
A 1 231 ILE 231 312 312 ILE ILE A . n 
A 1 232 THR 232 313 313 THR THR A . n 
A 1 233 GLN 233 314 314 GLN GLN A . n 
A 1 234 GLY 234 315 315 GLY GLY A . n 
A 1 235 ASN 235 316 316 ASN ASN A . n 
A 1 236 PRO 236 317 317 PRO PRO A . n 
A 1 237 ASN 237 318 318 ASN ASN A . n 
A 1 238 TYR 238 319 319 TYR TYR A . n 
A 1 239 ASP 239 320 320 ASP ASP A . n 
A 1 240 GLU 240 321 321 GLU GLU A . n 
A 1 241 ILE 241 322 322 ILE ILE A . n 
A 1 242 HIS 242 323 323 HIS HIS A . n 
A 1 243 TYR 243 324 324 TYR TYR A . n 
A 1 244 ILE 244 325 325 ILE ILE A . n 
A 1 245 ASN 245 326 326 ASN ASN A . n 
A 1 246 ALA 246 327 327 ALA ALA A . n 
A 1 247 LEU 247 328 328 LEU LEU A . n 
A 1 248 ALA 248 329 329 ALA ALA A . n 
A 1 249 PRO 249 330 330 PRO PRO A . n 
A 1 250 LEU 250 331 331 LEU LEU A . n 
A 1 251 LEU 251 332 332 LEU LEU A . n 
A 1 252 GLN 252 333 333 GLN GLN A . n 
A 1 253 GLN 253 334 334 GLN GLN A . n 
A 1 254 ALA 254 335 335 ALA ALA A . n 
A 1 255 GLY 255 336 336 GLY GLY A . n 
A 1 256 TRP 256 337 337 TRP TRP A . n 
A 1 257 ASP 257 338 338 ASP ASP A . n 
A 1 258 ALA 258 339 339 ALA ALA A . n 
A 1 259 THR 259 340 340 THR THR A . n 
A 1 260 PHE 260 341 341 PHE PHE A . n 
A 1 261 ILE 261 342 342 ILE ILE A . n 
A 1 262 VAL 262 343 343 VAL VAL A . n 
A 1 263 ASP 263 344 344 ASP ASP A . n 
A 1 264 GLN 264 345 345 GLN GLN A . n 
A 1 265 GLY 265 346 346 GLY GLY A . n 
A 1 266 ARG 266 347 347 ARG ARG A . n 
A 1 267 SER 267 348 348 SER SER A . n 
A 1 268 GLY 268 349 349 GLY GLY A . n 
A 1 269 VAL 269 350 350 VAL VAL A . n 
A 1 270 GLN 270 351 351 GLN GLN A . n 
A 1 271 ASN 271 352 352 ASN ASN A . n 
A 1 272 ILE 272 353 353 ILE ILE A . n 
A 1 273 ARG 273 354 354 ARG ARG A . n 
A 1 274 GLN 274 355 355 GLN GLN A . n 
A 1 275 GLN 275 356 356 GLN GLN A . n 
A 1 276 TRP 276 357 357 TRP TRP A . n 
A 1 277 GLY 277 358 358 GLY GLY A . n 
A 1 278 ASP 278 359 359 ASP ASP A . n 
A 1 279 TRP 279 360 360 TRP TRP A . n 
A 1 280 CYS 280 361 361 CYS CYS A . n 
A 1 281 ASN 281 362 362 ASN ASN A . n 
A 1 282 ILE 282 363 363 ILE ILE A . n 
A 1 283 LYS 283 364 364 LYS LYS A . n 
A 1 284 GLY 284 365 365 GLY GLY A . n 
A 1 285 ALA 285 366 366 ALA ALA A . n 
A 1 286 GLY 286 367 367 GLY GLY A . n 
A 1 287 PHE 287 368 368 PHE PHE A . n 
A 1 288 GLY 288 369 369 GLY GLY A . n 
A 1 289 THR 289 370 370 THR THR A . n 
A 1 290 ARG 290 371 371 ARG ARG A . n 
A 1 291 PRO 291 372 372 PRO PRO A . n 
A 1 292 THR 292 373 373 THR THR A . n 
A 1 293 THR 293 374 374 THR THR A . n 
A 1 294 ASN 294 375 375 ASN ASN A . n 
A 1 295 THR 295 376 376 THR THR A . n 
A 1 296 GLY 296 377 377 GLY GLY A . n 
A 1 297 SER 297 378 378 SER SER A . n 
A 1 298 GLN 298 379 379 GLN GLN A . n 
A 1 299 PHE 299 380 380 PHE PHE A . n 
A 1 300 ILE 300 381 381 ILE ILE A . n 
A 1 301 ASP 301 382 382 ASP ASP A . n 
A 1 302 SER 302 383 383 SER SER A . n 
A 1 303 ILE 303 384 384 ILE ILE A . n 
A 1 304 VAL 304 385 385 VAL VAL A . n 
A 1 305 TRP 305 386 386 TRP TRP A . n 
A 1 306 VAL 306 387 387 VAL VAL A . n 
A 1 307 LYS 307 388 388 LYS LYS A . n 
A 1 308 PRO 308 389 389 PRO PRO A . n 
A 1 309 GLY 309 390 390 GLY GLY A . n 
A 1 310 GLY 310 391 391 GLY GLY A . n 
A 1 311 GLU 311 392 392 GLU GLU A . n 
A 1 312 CYS 312 393 393 CYS CYS A . n 
A 1 313 ASP 313 394 394 ASP ASP A . n 
A 1 314 GLY 314 395 395 GLY GLY A . n 
A 1 315 THR 315 396 396 THR THR A . n 
A 1 316 SER 316 397 397 SER SER A . n 
A 1 317 ASN 317 398 398 ASN ASN A . n 
A 1 318 SER 318 399 399 SER SER A . n 
A 1 319 SER 319 400 400 SER SER A . n 
A 1 320 SER 320 401 401 SER SER A . n 
A 1 321 PRO 321 402 402 PRO PRO A . n 
A 1 322 ARG 322 403 403 ARG ARG A . n 
A 1 323 TYR 323 404 404 TYR TYR A . n 
A 1 324 ASP 324 405 405 ASP ASP A . n 
A 1 325 SER 325 406 406 SER SER A . n 
A 1 326 THR 326 407 407 THR THR A . n 
A 1 327 CYS 327 408 408 CYS CYS A . n 
A 1 328 SER 328 409 409 SER SER A . n 
A 1 329 LEU 329 410 410 LEU LEU A . n 
A 1 330 PRO 330 411 411 PRO PRO A . n 
A 1 331 ASP 331 412 412 ASP ASP A . n 
A 1 332 ALA 332 413 413 ALA ALA A . n 
A 1 333 ALA 333 414 414 ALA ALA A . n 
A 1 334 GLN 334 415 415 GLN GLN A . n 
A 1 335 PRO 335 416 416 PRO PRO A . n 
A 1 336 ALA 336 417 417 ALA ALA A . n 
A 1 337 PRO 337 418 418 PRO PRO A . n 
A 1 338 GLU 338 419 419 GLU GLU A . n 
A 1 339 ALA 339 420 420 ALA ALA A . n 
A 1 340 GLY 340 421 421 GLY GLY A . n 
A 1 341 THR 341 422 422 THR THR A . n 
A 1 342 TRP 342 423 423 TRP TRP A . n 
A 1 343 PHE 343 424 424 PHE PHE A . n 
A 1 344 GLN 344 425 425 GLN GLN A . n 
A 1 345 ALA 345 426 426 ALA ALA A . n 
A 1 346 TYR 346 427 427 TYR TYR A . n 
A 1 347 PHE 347 428 428 PHE PHE A . n 
A 1 348 GLN 348 429 429 GLN GLN A . n 
A 1 349 THR 349 430 430 THR THR A . n 
A 1 350 LEU 350 431 431 LEU LEU A . n 
A 1 351 VAL 351 432 432 VAL VAL A . n 
A 1 352 SER 352 433 433 SER SER A . n 
A 1 353 ALA 353 434 434 ALA ALA A . n 
A 1 354 ALA 354 435 435 ALA ALA A . n 
A 1 355 ASN 355 436 436 ASN ASN A . n 
A 1 356 PRO 356 437 437 PRO PRO A . n 
A 1 357 PRO 357 438 438 PRO PRO A . n 
A 1 358 LEU 358 439 439 LEU LEU A . n 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
B 2 HOH 1   501 323 HOH HOH A . 
B 2 HOH 2   502 260 HOH HOH A . 
B 2 HOH 3   503 110 HOH HOH A . 
B 2 HOH 4   504 176 HOH HOH A . 
B 2 HOH 5   505 177 HOH HOH A . 
B 2 HOH 6   506 212 HOH HOH A . 
B 2 HOH 7   507 327 HOH HOH A . 
B 2 HOH 8   508 100 HOH HOH A . 
B 2 HOH 9   509 82  HOH HOH A . 
B 2 HOH 10  510 117 HOH HOH A . 
B 2 HOH 11  511 330 HOH HOH A . 
B 2 HOH 12  512 305 HOH HOH A . 
B 2 HOH 13  513 112 HOH HOH A . 
B 2 HOH 14  514 148 HOH HOH A . 
B 2 HOH 15  515 208 HOH HOH A . 
B 2 HOH 16  516 105 HOH HOH A . 
B 2 HOH 17  517 189 HOH HOH A . 
B 2 HOH 18  518 129 HOH HOH A . 
B 2 HOH 19  519 86  HOH HOH A . 
B 2 HOH 20  520 133 HOH HOH A . 
B 2 HOH 21  521 52  HOH HOH A . 
B 2 HOH 22  522 152 HOH HOH A . 
B 2 HOH 23  523 125 HOH HOH A . 
B 2 HOH 24  524 40  HOH HOH A . 
B 2 HOH 25  525 131 HOH HOH A . 
B 2 HOH 26  526 145 HOH HOH A . 
B 2 HOH 27  527 154 HOH HOH A . 
B 2 HOH 28  528 22  HOH HOH A . 
B 2 HOH 29  529 247 HOH HOH A . 
B 2 HOH 30  530 120 HOH HOH A . 
B 2 HOH 31  531 4   HOH HOH A . 
B 2 HOH 32  532 73  HOH HOH A . 
B 2 HOH 33  533 46  HOH HOH A . 
B 2 HOH 34  534 128 HOH HOH A . 
B 2 HOH 35  535 211 HOH HOH A . 
B 2 HOH 36  536 242 HOH HOH A . 
B 2 HOH 37  537 200 HOH HOH A . 
B 2 HOH 38  538 301 HOH HOH A . 
B 2 HOH 39  539 26  HOH HOH A . 
B 2 HOH 40  540 167 HOH HOH A . 
B 2 HOH 41  541 91  HOH HOH A . 
B 2 HOH 42  542 8   HOH HOH A . 
B 2 HOH 43  543 183 HOH HOH A . 
B 2 HOH 44  544 102 HOH HOH A . 
B 2 HOH 45  545 221 HOH HOH A . 
B 2 HOH 46  546 89  HOH HOH A . 
B 2 HOH 47  547 245 HOH HOH A . 
B 2 HOH 48  548 97  HOH HOH A . 
B 2 HOH 49  549 2   HOH HOH A . 
B 2 HOH 50  550 165 HOH HOH A . 
B 2 HOH 51  551 191 HOH HOH A . 
B 2 HOH 52  552 29  HOH HOH A . 
B 2 HOH 53  553 144 HOH HOH A . 
B 2 HOH 54  554 62  HOH HOH A . 
B 2 HOH 55  555 68  HOH HOH A . 
B 2 HOH 56  556 60  HOH HOH A . 
B 2 HOH 57  557 161 HOH HOH A . 
B 2 HOH 58  558 74  HOH HOH A . 
B 2 HOH 59  559 55  HOH HOH A . 
B 2 HOH 60  560 47  HOH HOH A . 
B 2 HOH 61  561 12  HOH HOH A . 
B 2 HOH 62  562 56  HOH HOH A . 
B 2 HOH 63  563 194 HOH HOH A . 
B 2 HOH 64  564 197 HOH HOH A . 
B 2 HOH 65  565 21  HOH HOH A . 
B 2 HOH 66  566 27  HOH HOH A . 
B 2 HOH 67  567 70  HOH HOH A . 
B 2 HOH 68  568 109 HOH HOH A . 
B 2 HOH 69  569 63  HOH HOH A . 
B 2 HOH 70  570 226 HOH HOH A . 
B 2 HOH 71  571 196 HOH HOH A . 
B 2 HOH 72  572 7   HOH HOH A . 
B 2 HOH 73  573 14  HOH HOH A . 
B 2 HOH 74  574 202 HOH HOH A . 
B 2 HOH 75  575 276 HOH HOH A . 
B 2 HOH 76  576 187 HOH HOH A . 
B 2 HOH 77  577 20  HOH HOH A . 
B 2 HOH 78  578 108 HOH HOH A . 
B 2 HOH 79  579 33  HOH HOH A . 
B 2 HOH 80  580 156 HOH HOH A . 
B 2 HOH 81  581 113 HOH HOH A . 
B 2 HOH 82  582 1   HOH HOH A . 
B 2 HOH 83  583 16  HOH HOH A . 
B 2 HOH 84  584 213 HOH HOH A . 
B 2 HOH 85  585 134 HOH HOH A . 
B 2 HOH 86  586 250 HOH HOH A . 
B 2 HOH 87  587 43  HOH HOH A . 
B 2 HOH 88  588 54  HOH HOH A . 
B 2 HOH 89  589 81  HOH HOH A . 
B 2 HOH 90  590 23  HOH HOH A . 
B 2 HOH 91  591 69  HOH HOH A . 
B 2 HOH 92  592 85  HOH HOH A . 
B 2 HOH 93  593 151 HOH HOH A . 
B 2 HOH 94  594 192 HOH HOH A . 
B 2 HOH 95  595 127 HOH HOH A . 
B 2 HOH 96  596 18  HOH HOH A . 
B 2 HOH 97  597 119 HOH HOH A . 
B 2 HOH 98  598 17  HOH HOH A . 
B 2 HOH 99  599 28  HOH HOH A . 
B 2 HOH 100 600 42  HOH HOH A . 
B 2 HOH 101 601 38  HOH HOH A . 
B 2 HOH 102 602 259 HOH HOH A . 
B 2 HOH 103 603 171 HOH HOH A . 
B 2 HOH 104 604 30  HOH HOH A . 
B 2 HOH 105 605 67  HOH HOH A . 
B 2 HOH 106 606 49  HOH HOH A . 
B 2 HOH 107 607 31  HOH HOH A . 
B 2 HOH 108 608 114 HOH HOH A . 
B 2 HOH 109 609 9   HOH HOH A . 
B 2 HOH 110 610 15  HOH HOH A . 
B 2 HOH 111 611 223 HOH HOH A . 
B 2 HOH 112 612 149 HOH HOH A . 
B 2 HOH 113 613 224 HOH HOH A . 
B 2 HOH 114 614 78  HOH HOH A . 
B 2 HOH 115 615 115 HOH HOH A . 
B 2 HOH 116 616 263 HOH HOH A . 
B 2 HOH 117 617 233 HOH HOH A . 
B 2 HOH 118 618 172 HOH HOH A . 
B 2 HOH 119 619 6   HOH HOH A . 
B 2 HOH 120 620 83  HOH HOH A . 
B 2 HOH 121 621 75  HOH HOH A . 
B 2 HOH 122 622 214 HOH HOH A . 
B 2 HOH 123 623 99  HOH HOH A . 
B 2 HOH 124 624 77  HOH HOH A . 
B 2 HOH 125 625 95  HOH HOH A . 
B 2 HOH 126 626 11  HOH HOH A . 
B 2 HOH 127 627 36  HOH HOH A . 
B 2 HOH 128 628 179 HOH HOH A . 
B 2 HOH 129 629 32  HOH HOH A . 
B 2 HOH 130 630 48  HOH HOH A . 
B 2 HOH 131 631 58  HOH HOH A . 
B 2 HOH 132 632 10  HOH HOH A . 
B 2 HOH 133 633 19  HOH HOH A . 
B 2 HOH 134 634 61  HOH HOH A . 
B 2 HOH 135 635 215 HOH HOH A . 
B 2 HOH 136 636 126 HOH HOH A . 
B 2 HOH 137 637 5   HOH HOH A . 
B 2 HOH 138 638 71  HOH HOH A . 
B 2 HOH 139 639 87  HOH HOH A . 
B 2 HOH 140 640 146 HOH HOH A . 
B 2 HOH 141 641 269 HOH HOH A . 
B 2 HOH 142 642 3   HOH HOH A . 
B 2 HOH 143 643 124 HOH HOH A . 
B 2 HOH 144 644 66  HOH HOH A . 
B 2 HOH 145 645 199 HOH HOH A . 
B 2 HOH 146 646 325 HOH HOH A . 
B 2 HOH 147 647 98  HOH HOH A . 
B 2 HOH 148 648 57  HOH HOH A . 
B 2 HOH 149 649 53  HOH HOH A . 
B 2 HOH 150 650 136 HOH HOH A . 
B 2 HOH 151 651 186 HOH HOH A . 
B 2 HOH 152 652 228 HOH HOH A . 
B 2 HOH 153 653 104 HOH HOH A . 
B 2 HOH 154 654 107 HOH HOH A . 
B 2 HOH 155 655 84  HOH HOH A . 
B 2 HOH 156 656 59  HOH HOH A . 
B 2 HOH 157 657 140 HOH HOH A . 
B 2 HOH 158 658 234 HOH HOH A . 
B 2 HOH 159 659 88  HOH HOH A . 
B 2 HOH 160 660 143 HOH HOH A . 
B 2 HOH 161 661 45  HOH HOH A . 
B 2 HOH 162 662 130 HOH HOH A . 
B 2 HOH 163 663 25  HOH HOH A . 
B 2 HOH 164 664 24  HOH HOH A . 
B 2 HOH 165 665 217 HOH HOH A . 
B 2 HOH 166 666 65  HOH HOH A . 
B 2 HOH 167 667 157 HOH HOH A . 
B 2 HOH 168 668 35  HOH HOH A . 
B 2 HOH 169 669 162 HOH HOH A . 
B 2 HOH 170 670 64  HOH HOH A . 
B 2 HOH 171 671 158 HOH HOH A . 
B 2 HOH 172 672 230 HOH HOH A . 
B 2 HOH 173 673 13  HOH HOH A . 
B 2 HOH 174 674 326 HOH HOH A . 
B 2 HOH 175 675 163 HOH HOH A . 
B 2 HOH 176 676 96  HOH HOH A . 
B 2 HOH 177 677 51  HOH HOH A . 
B 2 HOH 178 678 106 HOH HOH A . 
B 2 HOH 179 679 44  HOH HOH A . 
B 2 HOH 180 680 137 HOH HOH A . 
B 2 HOH 181 681 116 HOH HOH A . 
B 2 HOH 182 682 168 HOH HOH A . 
B 2 HOH 183 683 150 HOH HOH A . 
B 2 HOH 184 684 248 HOH HOH A . 
B 2 HOH 185 685 34  HOH HOH A . 
B 2 HOH 186 686 93  HOH HOH A . 
B 2 HOH 187 687 90  HOH HOH A . 
B 2 HOH 188 688 41  HOH HOH A . 
B 2 HOH 189 689 72  HOH HOH A . 
B 2 HOH 190 690 122 HOH HOH A . 
B 2 HOH 191 691 184 HOH HOH A . 
B 2 HOH 192 692 159 HOH HOH A . 
B 2 HOH 193 693 94  HOH HOH A . 
B 2 HOH 194 694 101 HOH HOH A . 
B 2 HOH 195 695 169 HOH HOH A . 
B 2 HOH 196 696 37  HOH HOH A . 
B 2 HOH 197 697 236 HOH HOH A . 
B 2 HOH 198 698 139 HOH HOH A . 
B 2 HOH 199 699 103 HOH HOH A . 
B 2 HOH 200 700 203 HOH HOH A . 
B 2 HOH 201 701 141 HOH HOH A . 
B 2 HOH 202 702 164 HOH HOH A . 
B 2 HOH 203 703 80  HOH HOH A . 
B 2 HOH 204 704 39  HOH HOH A . 
B 2 HOH 205 705 181 HOH HOH A . 
B 2 HOH 206 706 160 HOH HOH A . 
B 2 HOH 207 707 118 HOH HOH A . 
B 2 HOH 208 708 138 HOH HOH A . 
B 2 HOH 209 709 239 HOH HOH A . 
B 2 HOH 210 710 121 HOH HOH A . 
B 2 HOH 211 711 92  HOH HOH A . 
B 2 HOH 212 712 185 HOH HOH A . 
B 2 HOH 213 713 261 HOH HOH A . 
B 2 HOH 214 714 132 HOH HOH A . 
B 2 HOH 215 715 79  HOH HOH A . 
B 2 HOH 216 716 303 HOH HOH A . 
B 2 HOH 217 717 155 HOH HOH A . 
B 2 HOH 218 718 76  HOH HOH A . 
B 2 HOH 219 719 328 HOH HOH A . 
B 2 HOH 220 720 50  HOH HOH A . 
B 2 HOH 221 721 135 HOH HOH A . 
B 2 HOH 222 722 205 HOH HOH A . 
B 2 HOH 223 723 288 HOH HOH A . 
B 2 HOH 224 724 111 HOH HOH A . 
B 2 HOH 225 725 198 HOH HOH A . 
B 2 HOH 226 726 256 HOH HOH A . 
B 2 HOH 227 727 271 HOH HOH A . 
B 2 HOH 228 728 273 HOH HOH A . 
B 2 HOH 229 729 304 HOH HOH A . 
B 2 HOH 230 730 231 HOH HOH A . 
B 2 HOH 231 731 123 HOH HOH A . 
B 2 HOH 232 732 195 HOH HOH A . 
B 2 HOH 233 733 170 HOH HOH A . 
B 2 HOH 234 734 229 HOH HOH A . 
B 2 HOH 235 735 244 HOH HOH A . 
B 2 HOH 236 736 292 HOH HOH A . 
B 2 HOH 237 737 300 HOH HOH A . 
B 2 HOH 238 738 206 HOH HOH A . 
B 2 HOH 239 739 227 HOH HOH A . 
B 2 HOH 240 740 190 HOH HOH A . 
B 2 HOH 241 741 209 HOH HOH A . 
B 2 HOH 242 742 219 HOH HOH A . 
B 2 HOH 243 743 188 HOH HOH A . 
B 2 HOH 244 744 204 HOH HOH A . 
B 2 HOH 245 745 266 HOH HOH A . 
B 2 HOH 246 746 280 HOH HOH A . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.dependencies 
_software.description 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.pdbx_ordinal 
_software.type 
_software.version 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX    ? ? 1 ? 1.19.2_4158 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHENIX    ? ? 2 ? 1.19.2_4158 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? STARGazer ? ? 3 ? .           
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8W4Y 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     55.350 
_cell.length_a_esd                 ? 
_cell.length_b                     67.920 
_cell.length_b_esd                 ? 
_cell.length_c                     89.790 
_cell.length_c_esd                 ? 
_cell.volume                       337554.012 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8W4Y 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                19 
_symmetry.space_group_name_Hall            'P 2ac 2ab' 
_symmetry.space_group_name_H-M             'P 21 21 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
loop_
_exptl.absorpt_coefficient_mu 
_exptl.absorpt_correction_T_max 
_exptl.absorpt_correction_T_min 
_exptl.absorpt_correction_type 
_exptl.absorpt_process_details 
_exptl.entry_id 
_exptl.crystals_number 
_exptl.details 
_exptl.method 
_exptl.method_details 
? ? ? ? ? 8W4Y 1 ? 'X-RAY DIFFRACTION'   ? 
? ? ? ? ? 8W4Y ? ? 'NEUTRON DIFFRACTION' ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.20 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          44.06 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    
;polyethylene glycol 3350, 
sodium chloride, 
2-methyl-2,4-pentandiol,
acetate buffer,
;
_exptl_crystal_grow.pdbx_pH_range   5.2-5.7 
_exptl_crystal_grow.temp            293 
# 
loop_
_diffrn.ambient_environment 
_diffrn.ambient_temp 
_diffrn.ambient_temp_details 
_diffrn.ambient_temp_esd 
_diffrn.crystal_id 
_diffrn.crystal_support 
_diffrn.crystal_treatment 
_diffrn.details 
_diffrn.id 
_diffrn.ambient_pressure 
_diffrn.ambient_pressure_esd 
_diffrn.ambient_pressure_gt 
_diffrn.ambient_pressure_lt 
_diffrn.ambient_temp_gt 
_diffrn.ambient_temp_lt 
_diffrn.pdbx_serial_crystal_experiment 
? 298 ? ? 1 ? ? ? 1 ? ? ? ? ? ? N 
? 298 ? ? 1 ? ? ? 2 ? ? ? ? ? ? N 
# 
loop_
_diffrn_detector.details 
_diffrn_detector.detector 
_diffrn_detector.diffrn_id 
_diffrn_detector.type 
_diffrn_detector.area_resol_mean 
_diffrn_detector.dtime 
_diffrn_detector.pdbx_frames_total 
_diffrn_detector.pdbx_collection_time_total 
_diffrn_detector.pdbx_collection_date 
_diffrn_detector.pdbx_frequency 
_diffrn_detector.id 
_diffrn_detector.number_of_axes 
? PIXEL          1 'DECTRIS PILATUS 2M' ? ? ? ? 2017-04-16 ? ? ? 
? DIFFRACTOMETER 2 iBIX                 ? ? ? ? 2017-02-05 ? ? ? 
# 
loop_
_diffrn_radiation.collimation 
_diffrn_radiation.diffrn_id 
_diffrn_radiation.filter_edge 
_diffrn_radiation.inhomogeneity 
_diffrn_radiation.monochromator 
_diffrn_radiation.polarisn_norm 
_diffrn_radiation.polarisn_ratio 
_diffrn_radiation.probe 
_diffrn_radiation.type 
_diffrn_radiation.xray_symbol 
_diffrn_radiation.wavelength_id 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l 
_diffrn_radiation.pdbx_wavelength_list 
_diffrn_radiation.pdbx_wavelength 
_diffrn_radiation.pdbx_diffrn_protocol 
_diffrn_radiation.pdbx_analyzer 
_diffrn_radiation.pdbx_scattering_type 
? 1 ? ? ? ? ? ? ? ? 1 M ? ? 'SINGLE WAVELENGTH' ? x-ray   
? 2 ? ? ? ? ? ? ? ? 2 L ? ? LAUE                ? neutron 
# 
loop_
_diffrn_radiation_wavelength.id 
_diffrn_radiation_wavelength.wavelength 
_diffrn_radiation_wavelength.wt 
1 1.0 1.0 
2 2.9 1.0 
3 5.6 1.0 
# 
loop_
_diffrn_source.current 
_diffrn_source.details 
_diffrn_source.diffrn_id 
_diffrn_source.power 
_diffrn_source.size 
_diffrn_source.source 
_diffrn_source.target 
_diffrn_source.type 
_diffrn_source.voltage 
_diffrn_source.take-off_angle 
_diffrn_source.pdbx_wavelength_list 
_diffrn_source.pdbx_wavelength 
_diffrn_source.pdbx_synchrotron_beamline 
_diffrn_source.pdbx_synchrotron_site 
? ? 1 ? ? SYNCHROTRON         ? 'PHOTON FACTORY BEAMLINE AR-NE3A' ? ? 1.0     ? AR-NE3A 'Photon Factory' 
? ? 2 ? ? 'SPALLATION SOURCE' ? 'J-PARC MLF BEAMLINE BL-03'       ? ? 2.9-5.6 ? BL-03   'JPARC MLF'      
# 
loop_
_reflns.B_iso_Wilson_estimate 
_reflns.entry_id 
_reflns.data_reduction_details 
_reflns.data_reduction_method 
_reflns.d_resolution_high 
_reflns.d_resolution_low 
_reflns.details 
_reflns.limit_h_max 
_reflns.limit_h_min 
_reflns.limit_k_max 
_reflns.limit_k_min 
_reflns.limit_l_max 
_reflns.limit_l_min 
_reflns.number_all 
_reflns.number_obs 
_reflns.observed_criterion 
_reflns.observed_criterion_F_max 
_reflns.observed_criterion_F_min 
_reflns.observed_criterion_I_max 
_reflns.observed_criterion_I_min 
_reflns.observed_criterion_sigma_F 
_reflns.observed_criterion_sigma_I 
_reflns.percent_possible_obs 
_reflns.R_free_details 
_reflns.Rmerge_F_all 
_reflns.Rmerge_F_obs 
_reflns.Friedel_coverage 
_reflns.number_gt 
_reflns.threshold_expression 
_reflns.pdbx_redundancy 
_reflns.pdbx_netI_over_av_sigmaI 
_reflns.pdbx_netI_over_sigmaI 
_reflns.pdbx_res_netI_over_av_sigmaI_2 
_reflns.pdbx_res_netI_over_sigmaI_2 
_reflns.pdbx_chi_squared 
_reflns.pdbx_scaling_rejects 
_reflns.pdbx_d_res_high_opt 
_reflns.pdbx_d_res_low_opt 
_reflns.pdbx_d_res_opt_method 
_reflns.phase_calculation_details 
_reflns.pdbx_Rrim_I_all 
_reflns.pdbx_Rpim_I_all 
_reflns.pdbx_d_opt 
_reflns.pdbx_number_measured_all 
_reflns.pdbx_diffrn_id 
_reflns.pdbx_ordinal 
_reflns.pdbx_CC_half 
_reflns.pdbx_CC_star 
_reflns.pdbx_R_split 
_reflns.pdbx_Rmerge_I_obs 
_reflns.pdbx_Rmerge_I_all 
_reflns.pdbx_Rsym_value 
_reflns.pdbx_CC_split_method 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1] 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2] 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3] 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1] 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2] 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3] 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1] 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2] 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3] 
_reflns.pdbx_aniso_diffraction_limit_1 
_reflns.pdbx_aniso_diffraction_limit_2 
_reflns.pdbx_aniso_diffraction_limit_3 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1] 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2] 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3] 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1] 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2] 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3] 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1] 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2] 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3] 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3 
_reflns.pdbx_orthogonalization_convention 
_reflns.pdbx_percent_possible_ellipsoidal 
_reflns.pdbx_percent_possible_spherical 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous 
_reflns.pdbx_percent_possible_spherical_anomalous 
_reflns.pdbx_redundancy_anomalous 
_reflns.pdbx_CC_half_anomalous 
_reflns.pdbx_absDiff_over_sigma_anomalous 
_reflns.pdbx_percent_possible_anomalous 
_reflns.pdbx_observed_signal_threshold 
_reflns.pdbx_signal_type 
_reflns.pdbx_signal_details 
_reflns.pdbx_signal_software_id 
12.52 8W4Y ? ? 1.4  100  ? ? ? ? ? ? ? ? 65352 ? ? ? ? ? ? ? 96.9 ? ? ? ? ? ? 6.7 ? 23.3 ? ? ? ? ? ? ? ? ? ? ? ? 1 1 ? ? ? 0.075 ? 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
?     8W4Y ? ? 2.15 20.9 ? ? ? ? ? ? ? ? 18875 ? ? ? ? ? ? ? 91.2 ? ? ? ? ? ? 2.2 ? 6.2  ? ? ? ? ? ? ? ? ? ? ? ? 2 2 ? ? ? 0.289 ? 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_reflns_shell.d_res_high 
_reflns_shell.d_res_low 
_reflns_shell.meanI_over_sigI_all 
_reflns_shell.meanI_over_sigI_obs 
_reflns_shell.number_measured_all 
_reflns_shell.number_measured_obs 
_reflns_shell.number_possible 
_reflns_shell.number_unique_all 
_reflns_shell.number_unique_obs 
_reflns_shell.percent_possible_obs 
_reflns_shell.Rmerge_F_all 
_reflns_shell.Rmerge_F_obs 
_reflns_shell.meanI_over_sigI_gt 
_reflns_shell.meanI_over_uI_all 
_reflns_shell.meanI_over_uI_gt 
_reflns_shell.number_measured_gt 
_reflns_shell.number_unique_gt 
_reflns_shell.percent_possible_gt 
_reflns_shell.Rmerge_F_gt 
_reflns_shell.Rmerge_I_gt 
_reflns_shell.pdbx_redundancy 
_reflns_shell.pdbx_chi_squared 
_reflns_shell.pdbx_netI_over_sigmaI_all 
_reflns_shell.pdbx_netI_over_sigmaI_obs 
_reflns_shell.pdbx_Rrim_I_all 
_reflns_shell.pdbx_Rpim_I_all 
_reflns_shell.pdbx_rejects 
_reflns_shell.pdbx_ordinal 
_reflns_shell.pdbx_diffrn_id 
_reflns_shell.pdbx_CC_half 
_reflns_shell.pdbx_CC_star 
_reflns_shell.pdbx_R_split 
_reflns_shell.percent_possible_all 
_reflns_shell.Rmerge_I_all 
_reflns_shell.Rmerge_I_obs 
_reflns_shell.pdbx_Rsym_value 
_reflns_shell.pdbx_percent_possible_ellipsoidal 
_reflns_shell.pdbx_percent_possible_spherical 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous 
_reflns_shell.pdbx_percent_possible_spherical_anomalous 
_reflns_shell.pdbx_redundancy_anomalous 
_reflns_shell.pdbx_CC_half_anomalous 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous 
_reflns_shell.pdbx_percent_possible_anomalous 
1.40 1.42 ? ? ? ? ? ? 3176 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 1 1 ? ? ? ? ? 0.432 ? ? ? ? ? ? ? ? ? 
2.15 2.23 ? ? ? ? ? ? 2108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 2 2 ? ? ? ? ? 0.540 ? ? ? ? ? ? ? ? ? 
# 
loop_
_refine.aniso_B[1][1] 
_refine.aniso_B[1][2] 
_refine.aniso_B[1][3] 
_refine.aniso_B[2][2] 
_refine.aniso_B[2][3] 
_refine.aniso_B[3][3] 
_refine.B_iso_max 
_refine.B_iso_mean 
_refine.B_iso_min 
_refine.correlation_coeff_Fo_to_Fc 
_refine.correlation_coeff_Fo_to_Fc_free 
_refine.details 
_refine.diff_density_max 
_refine.diff_density_max_esd 
_refine.diff_density_min 
_refine.diff_density_min_esd 
_refine.diff_density_rms 
_refine.diff_density_rms_esd 
_refine.entry_id 
_refine.pdbx_refine_id 
_refine.ls_abs_structure_details 
_refine.ls_abs_structure_Flack 
_refine.ls_abs_structure_Flack_esd 
_refine.ls_abs_structure_Rogers 
_refine.ls_abs_structure_Rogers_esd 
_refine.ls_d_res_high 
_refine.ls_d_res_low 
_refine.ls_extinction_coef 
_refine.ls_extinction_coef_esd 
_refine.ls_extinction_expression 
_refine.ls_extinction_method 
_refine.ls_goodness_of_fit_all 
_refine.ls_goodness_of_fit_all_esd 
_refine.ls_goodness_of_fit_obs 
_refine.ls_goodness_of_fit_obs_esd 
_refine.ls_hydrogen_treatment 
_refine.ls_matrix_type 
_refine.ls_number_constraints 
_refine.ls_number_parameters 
_refine.ls_number_reflns_all 
_refine.ls_number_reflns_obs 
_refine.ls_number_reflns_R_free 
_refine.ls_number_reflns_R_work 
_refine.ls_number_restraints 
_refine.ls_percent_reflns_obs 
_refine.ls_percent_reflns_R_free 
_refine.ls_R_factor_all 
_refine.ls_R_factor_obs 
_refine.ls_R_factor_R_free 
_refine.ls_R_factor_R_free_error 
_refine.ls_R_factor_R_free_error_details 
_refine.ls_R_factor_R_work 
_refine.ls_R_Fsqd_factor_obs 
_refine.ls_R_I_factor_obs 
_refine.ls_redundancy_reflns_all 
_refine.ls_redundancy_reflns_obs 
_refine.ls_restrained_S_all 
_refine.ls_restrained_S_obs 
_refine.ls_shift_over_esd_max 
_refine.ls_shift_over_esd_mean 
_refine.ls_structure_factor_coef 
_refine.ls_weighting_details 
_refine.ls_weighting_scheme 
_refine.ls_wR_factor_all 
_refine.ls_wR_factor_obs 
_refine.ls_wR_factor_R_free 
_refine.ls_wR_factor_R_work 
_refine.occupancy_max 
_refine.occupancy_min 
_refine.solvent_model_details 
_refine.solvent_model_param_bsol 
_refine.solvent_model_param_ksol 
_refine.pdbx_R_complete 
_refine.ls_R_factor_gt 
_refine.ls_goodness_of_fit_gt 
_refine.ls_goodness_of_fit_ref 
_refine.ls_shift_over_su_max 
_refine.ls_shift_over_su_max_lt 
_refine.ls_shift_over_su_mean 
_refine.ls_shift_over_su_mean_lt 
_refine.pdbx_ls_sigma_I 
_refine.pdbx_ls_sigma_F 
_refine.pdbx_ls_sigma_Fsqd 
_refine.pdbx_data_cutoff_high_absF 
_refine.pdbx_data_cutoff_high_rms_absF 
_refine.pdbx_data_cutoff_low_absF 
_refine.pdbx_isotropic_thermal_model 
_refine.pdbx_ls_cross_valid_method 
_refine.pdbx_method_to_determine_struct 
_refine.pdbx_starting_model 
_refine.pdbx_stereochemistry_target_values 
_refine.pdbx_R_Free_selection_details 
_refine.pdbx_stereochem_target_val_spec_case 
_refine.pdbx_overall_ESU_R 
_refine.pdbx_overall_ESU_R_Free 
_refine.pdbx_solvent_vdw_probe_radii 
_refine.pdbx_solvent_ion_probe_radii 
_refine.pdbx_solvent_shrinkage_radii 
_refine.pdbx_real_space_R 
_refine.pdbx_density_correlation 
_refine.pdbx_pd_number_of_powder_patterns 
_refine.pdbx_pd_number_of_points 
_refine.pdbx_pd_meas_number_of_points 
_refine.pdbx_pd_proc_ls_prof_R_factor 
_refine.pdbx_pd_proc_ls_prof_wR_factor 
_refine.pdbx_pd_Marquardt_correlation_coeff 
_refine.pdbx_pd_Fsqrd_R_factor 
_refine.pdbx_pd_ls_matrix_band_width 
_refine.pdbx_overall_phase_error 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI 
_refine.pdbx_overall_SU_R_free_Blow_DPI 
_refine.pdbx_overall_SU_R_Blow_DPI 
_refine.pdbx_TLS_residual_ADP_flag 
_refine.pdbx_diffrn_id 
_refine.overall_SU_B 
_refine.overall_SU_ML 
_refine.overall_SU_R_Cruickshank_DPI 
_refine.overall_SU_R_free 
_refine.overall_FOM_free_R_set 
_refine.overall_FOM_work_R_set 
_refine.pdbx_average_fsc_overall 
_refine.pdbx_average_fsc_work 
_refine.pdbx_average_fsc_free 
? ? ? ? ? ? ? 20.29 ? ? ? ? ? ? ? ? ? ? 8W4Y 'X-RAY DIFFRACTION'   ? ? ? ? ? 1.40 47.12 ? ? ? ? ? ? ? ? ? ? ? ? ? 65296 3290 61998 
? 96.92 5.04 ? 0.1461 0.1635 ? ? 0.1452 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 'FLAT BULK SOLVENT MODEL' ? ? ? ? ? ? ? ? ? ? ? 1.37 ? ? 
? ? ? 'FREE R-VALUE' 'MOLECULAR REPLACEMENT' ? 'GeoStd + Monomer Library + CDL v1.2' ? ? ? ? 1.1100 ? 0.9000 ? ? ? ? ? ? ? ? ? ? 
15.6354 ? ? ? ? ? ? 0.1170 ? ? ? ? ? ? ? 
? ? ? ? ? ? ? ?     ? ? ? ? ? ? ? ? ? ? 8W4Y 'NEUTRON DIFFRACTION' ? ? ? ? ? 2.15 20.4  ? ? ? ? ? ? ? ? ? ? ? ? ? 18124 ?    ?     
? 94.73 ?    ? ?      0.1767 ? ? 0.1554 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 'FLAT BULK SOLVENT MODEL' ? ? ? ? ? ? ? ? ? ? ? ?    ? ? 
? ? ? 'FREE R-VALUE' 'MOLECULAR REPLACEMENT' ? 'GeoStd + Monomer Library + CDL v1.2' ? ? ? ? 1.1100 ? 0.9000 ? ? ? ? ? ? ? ? ? ? 
15.6354 ? ? ? ? 2 ? 0.1170 ? ? ? ? ? ? ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.40 
_refine_hist.d_res_low                        47.12 
_refine_hist.number_atoms_solvent             246 
_refine_hist.number_atoms_total               2956 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        2710 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         0 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0114  ? 2955 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.0437  ? 4076 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0813  ? 452  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0085  ? 549  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 14.3738 ? 1052 ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.40 1.42  . . 123 2508 94.40 . . . . 0.2265 . . . . . . . . . . . 0.2432 
'X-RAY DIFFRACTION' 1.42 1.44  . . 152 2476 95.15 . . . . 0.2041 . . . . . . . . . . . 0.2215 
'X-RAY DIFFRACTION' 1.44 1.46  . . 128 2510 95.10 . . . . 0.1949 . . . . . . . . . . . 0.2170 
'X-RAY DIFFRACTION' 1.46 1.49  . . 151 2485 95.13 . . . . 0.1922 . . . . . . . . . . . 0.2312 
'X-RAY DIFFRACTION' 1.49 1.51  . . 114 2520 95.54 . . . . 0.1881 . . . . . . . . . . . 0.2346 
'X-RAY DIFFRACTION' 1.51 1.54  . . 145 2507 95.36 . . . . 0.1870 . . . . . . . . . . . 0.2248 
'X-RAY DIFFRACTION' 1.54 1.57  . . 143 2506 95.84 . . . . 0.1913 . . . . . . . . . . . 0.1800 
'X-RAY DIFFRACTION' 1.57 1.60  . . 126 2548 96.19 . . . . 0.1762 . . . . . . . . . . . 0.1925 
'X-RAY DIFFRACTION' 1.60 1.64  . . 149 2541 96.24 . . . . 0.1822 . . . . . . . . . . . 0.2024 
'X-RAY DIFFRACTION' 1.64 1.68  . . 124 2563 96.31 . . . . 0.1701 . . . . . . . . . . . 0.2008 
'X-RAY DIFFRACTION' 1.68 1.72  . . 106 2575 96.37 . . . . 0.1680 . . . . . . . . . . . 0.2009 
'X-RAY DIFFRACTION' 1.72 1.76  . . 136 2536 96.71 . . . . 0.1684 . . . . . . . . . . . 0.1951 
'X-RAY DIFFRACTION' 1.76 1.82  . . 132 2572 96.88 . . . . 0.1575 . . . . . . . . . . . 0.1783 
'X-RAY DIFFRACTION' 1.82 1.87  . . 171 2546 97.11 . . . . 0.1534 . . . . . . . . . . . 0.1720 
'X-RAY DIFFRACTION' 1.87 1.94  . . 142 2593 97.12 . . . . 0.1621 . . . . . . . . . . . 0.1830 
'X-RAY DIFFRACTION' 1.94 2.02  . . 135 2572 97.83 . . . . 0.1496 . . . . . . . . . . . 0.1569 
'X-RAY DIFFRACTION' 2.02 2.11  . . 143 2604 97.45 . . . . 0.1466 . . . . . . . . . . . 0.1556 
'X-RAY DIFFRACTION' 2.11 2.22  . . 142 2609 98.29 . . . . 0.1372 . . . . . . . . . . . 0.1727 
'X-RAY DIFFRACTION' 2.22 2.36  . . 118 2653 97.92 . . . . 0.1359 . . . . . . . . . . . 0.1224 
'X-RAY DIFFRACTION' 2.36 2.54  . . 126 2649 98.47 . . . . 0.1359 . . . . . . . . . . . 0.1516 
'X-RAY DIFFRACTION' 2.54 2.80  . . 151 2654 98.80 . . . . 0.1343 . . . . . . . . . . . 0.1483 
'X-RAY DIFFRACTION' 2.80 3.20  . . 133 2695 98.92 . . . . 0.1364 . . . . . . . . . . . 0.1589 
'X-RAY DIFFRACTION' 3.21 4.04  . . 150 2716 99.07 . . . . 0.1118 . . . . . . . . . . . 0.1406 
'X-RAY DIFFRACTION' 4.04 47.12 . . 150 2860 99.47 . . . . 0.1232 . . . . . . . . . . . 0.1363 
# 
_struct.entry_id                     8W4Y 
_struct.title                        
'Neutron structure of cellulase Cel6A from Phanerochaete chrysosporium at room temperature, low-D2O-solvent' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8W4Y 
_struct_keywords.text            'Cellulase, Glycoside hydrolase family 6, Cellobiohydrolase II, HYDROLASE' 
_struct_keywords.pdbx_keywords   HYDROLASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    H3K419_PHACH 
_struct_ref.pdbx_db_accession          H3K419 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;SANNPWTGFQIFLSPYYANEVAAAAKQITDPTLSSKAASVANIPTFTWLDSVAKIPDLGTYLASASALGKSTGTKQLVQI
VIYDLPDRDCAAKASNGEFSIANNGQANYENYIDQIVAQIQQFPDVRVVAVIEPDSLANLVTNLNVQKCANAKTTYLACV
NYALTNLAKVGVYMYMDAGHAGWLGWPANLSPAAQLFTQVWQNAGKSPFIKGLATNVANYNALQAASPDPITQGNPNYDE
IHYINALAPLLQQAGWDATFIVDQGRSGVQNIRQQWGDWCNIKGAGFGTRPTTNTGSQFIDSIVWVKPGGECDGTSNSSS
PRYDSTCSLPDAAQPAPEAGTWFQAYFQTLVSAANPPL
;
_struct_ref.pdbx_align_begin           82 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              8W4Y 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 358 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             H3K419 
_struct_ref_seq.db_align_beg                  82 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  439 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       82 
_struct_ref_seq.pdbx_auth_seq_align_end       439 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 0     ? 
1 MORE         0     ? 
1 'SSA (A^2)'  14210 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 14  ? GLN A 27  ? SER A 95  GLN A 108 1 ? 14 
HELX_P HELX_P2  AA2 ASP A 30  ? VAL A 40  ? ASP A 111 VAL A 121 1 ? 11 
HELX_P HELX_P3  AA3 ALA A 41  ? ILE A 43  ? ALA A 122 ILE A 124 5 ? 3  
HELX_P HELX_P4  AA4 SER A 51  ? ALA A 53  ? SER A 132 ALA A 134 5 ? 3  
HELX_P HELX_P5  AA5 LYS A 54  ? GLY A 73  ? LYS A 135 GLY A 154 1 ? 20 
HELX_P HELX_P6  AA6 ASN A 104 ? GLN A 121 ? ASN A 185 GLN A 202 1 ? 18 
HELX_P HELX_P7  AA7 ALA A 138 ? ASN A 143 ? ALA A 219 ASN A 224 1 ? 6  
HELX_P HELX_P8  AA8 VAL A 146 ? VAL A 170 ? VAL A 227 VAL A 251 1 ? 25 
HELX_P HELX_P9  AA9 TRP A 186 ? ALA A 204 ? TRP A 267 ALA A 285 1 ? 19 
HELX_P HELX_P10 AB1 ASP A 229 ? GLN A 233 ? ASP A 310 GLN A 314 5 ? 5  
HELX_P HELX_P11 AB2 ASP A 239 ? ALA A 254 ? ASP A 320 ALA A 335 1 ? 16 
HELX_P HELX_P12 AB3 ASP A 324 ? LEU A 329 ? ASP A 405 LEU A 410 5 ? 6  
HELX_P HELX_P13 AB4 PHE A 343 ? ALA A 353 ? PHE A 424 ALA A 434 1 ? 11 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 90  SG A ? ? 1_555 A CYS 149 SG ? ? A CYS 171 A CYS 230 1_555 ? ? ? ? ? ? ? 2.020 ? ? 
disulf2 disulf ? ? A CYS 90  SG B ? ? 1_555 A CYS 149 SG ? ? A CYS 171 A CYS 230 1_555 ? ? ? ? ? ? ? 2.020 ? ? 
disulf3 disulf ? ? A CYS 280 SG ? ? ? 1_555 A CYS 327 SG A ? A CYS 361 A CYS 408 1_555 ? ? ? ? ? ? ? 2.015 ? ? 
disulf4 disulf ? ? A CYS 280 SG ? ? ? 1_555 A CYS 327 SG B ? A CYS 361 A CYS 408 1_555 ? ? ? ? ? ? ? 2.033 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 90  A CYS A 149 ? CYS A 171 ? 1_555 CYS A 230 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS A 90  B CYS A 149 ? CYS A 171 ? 1_555 CYS A 230 ? 1_555 SG SG . . . None 'Disulfide bridge' 
3 CYS A 280 ? CYS A 327 A CYS A 361 ? 1_555 CYS A 408 ? 1_555 SG SG . . . None 'Disulfide bridge' 
4 CYS A 280 ? CYS A 327 B CYS A 361 ? 1_555 CYS A 408 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 GLN 334 A . ? GLN 415 A PRO 335 A ? PRO 416 A 1 -7.74 
2 ASN 355 A . ? ASN 436 A PRO 356 A ? PRO 437 A 1 2.50  
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 3 ? 
AA2 ? 7 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? parallel 
AA1 2 3 ? parallel 
AA2 1 2 ? parallel 
AA2 2 3 ? parallel 
AA2 3 4 ? parallel 
AA2 4 5 ? parallel 
AA2 5 6 ? parallel 
AA2 6 7 ? parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLN A 10  ? ILE A 11  ? GLN A 91  ILE A 92  
AA1 2 GLN A 76  ? ILE A 82  ? GLN A 157 ILE A 163 
AA1 3 THR A 47  ? LEU A 49  ? THR A 128 LEU A 130 
AA2 1 GLN A 10  ? ILE A 11  ? GLN A 91  ILE A 92  
AA2 2 GLN A 76  ? ILE A 82  ? GLN A 157 ILE A 163 
AA2 3 ARG A 127 ? ILE A 132 ? ARG A 208 ILE A 213 
AA2 4 TYR A 173 ? ASP A 177 ? TYR A 254 ASP A 258 
AA2 5 ILE A 210 ? THR A 215 ? ILE A 291 THR A 296 
AA2 6 THR A 259 ? ASP A 263 ? THR A 340 ASP A 344 
AA2 7 ILE A 300 ? VAL A 304 ? ILE A 381 VAL A 385 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N GLN A 10  ? N GLN A 91  O LEU A 77  ? O LEU A 158 
AA1 2 3 O VAL A 81  ? O VAL A 162 N LEU A 49  ? N LEU A 130 
AA2 1 2 N GLN A 10  ? N GLN A 91  O LEU A 77  ? O LEU A 158 
AA2 2 3 N VAL A 78  ? N VAL A 159 O ARG A 127 ? O ARG A 208 
AA2 3 4 N ALA A 130 ? N ALA A 211 O TYR A 173 ? O TYR A 254 
AA2 4 5 N MET A 176 ? N MET A 257 O GLY A 212 ? O GLY A 293 
AA2 5 6 N THR A 215 ? N THR A 296 O ASP A 263 ? O ASP A 344 
AA2 6 7 N VAL A 262 ? N VAL A 343 O VAL A 304 ? O VAL A 385 
# 
_pdbx_entry_details.entry_id                   8W4Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 H   A ASP 405 ? A O A HOH 517 ? ? 1.60 
2 1 NE2 A GLN 356 ? B O A HOH 501 ? ? 2.01 
3 1 O   A TYR 404 ? B O A HOH 502 ? ? 2.11 
4 1 OE1 A GLN 429 ? ? O A HOH 503 ? ? 2.14 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 TYR A 164 ? ? -150.39 72.30   
2 1 ASP A 165 ? ? -151.92 32.23   
3 1 ASN A 184 ? ? -108.32 69.78   
4 1 GLU A 214 ? ? 52.73   74.84   
5 1 SER A 217 ? ? -121.65 -86.21  
6 1 TRP A 264 ? ? -113.46 -70.53  
7 1 ASN A 300 ? ? -110.91 -162.20 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z           
2 x+1/2,-y+1/2,-z 
3 -x,y+1/2,-z+1/2 
4 -x+1/2,-y,z+1/2 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
HOH O    O N N 158 
HOH H1   H N N 159 
HOH H2   H N N 160 
ILE N    N N N 161 
ILE CA   C N S 162 
ILE C    C N N 163 
ILE O    O N N 164 
ILE CB   C N S 165 
ILE CG1  C N N 166 
ILE CG2  C N N 167 
ILE CD1  C N N 168 
ILE OXT  O N N 169 
ILE H    H N N 170 
ILE H2   H N N 171 
ILE HA   H N N 172 
ILE HB   H N N 173 
ILE HG12 H N N 174 
ILE HG13 H N N 175 
ILE HG21 H N N 176 
ILE HG22 H N N 177 
ILE HG23 H N N 178 
ILE HD11 H N N 179 
ILE HD12 H N N 180 
ILE HD13 H N N 181 
ILE HXT  H N N 182 
LEU N    N N N 183 
LEU CA   C N S 184 
LEU C    C N N 185 
LEU O    O N N 186 
LEU CB   C N N 187 
LEU CG   C N N 188 
LEU CD1  C N N 189 
LEU CD2  C N N 190 
LEU OXT  O N N 191 
LEU H    H N N 192 
LEU H2   H N N 193 
LEU HA   H N N 194 
LEU HB2  H N N 195 
LEU HB3  H N N 196 
LEU HG   H N N 197 
LEU HD11 H N N 198 
LEU HD12 H N N 199 
LEU HD13 H N N 200 
LEU HD21 H N N 201 
LEU HD22 H N N 202 
LEU HD23 H N N 203 
LEU HXT  H N N 204 
LYS N    N N N 205 
LYS CA   C N S 206 
LYS C    C N N 207 
LYS O    O N N 208 
LYS CB   C N N 209 
LYS CG   C N N 210 
LYS CD   C N N 211 
LYS CE   C N N 212 
LYS NZ   N N N 213 
LYS OXT  O N N 214 
LYS H    H N N 215 
LYS H2   H N N 216 
LYS HA   H N N 217 
LYS HB2  H N N 218 
LYS HB3  H N N 219 
LYS HG2  H N N 220 
LYS HG3  H N N 221 
LYS HD2  H N N 222 
LYS HD3  H N N 223 
LYS HE2  H N N 224 
LYS HE3  H N N 225 
LYS HZ1  H N N 226 
LYS HZ2  H N N 227 
LYS HZ3  H N N 228 
LYS HXT  H N N 229 
MET N    N N N 230 
MET CA   C N S 231 
MET C    C N N 232 
MET O    O N N 233 
MET CB   C N N 234 
MET CG   C N N 235 
MET SD   S N N 236 
MET CE   C N N 237 
MET OXT  O N N 238 
MET H    H N N 239 
MET H2   H N N 240 
MET HA   H N N 241 
MET HB2  H N N 242 
MET HB3  H N N 243 
MET HG2  H N N 244 
MET HG3  H N N 245 
MET HE1  H N N 246 
MET HE2  H N N 247 
MET HE3  H N N 248 
MET HXT  H N N 249 
PHE N    N N N 250 
PHE CA   C N S 251 
PHE C    C N N 252 
PHE O    O N N 253 
PHE CB   C N N 254 
PHE CG   C Y N 255 
PHE CD1  C Y N 256 
PHE CD2  C Y N 257 
PHE CE1  C Y N 258 
PHE CE2  C Y N 259 
PHE CZ   C Y N 260 
PHE OXT  O N N 261 
PHE H    H N N 262 
PHE H2   H N N 263 
PHE HA   H N N 264 
PHE HB2  H N N 265 
PHE HB3  H N N 266 
PHE HD1  H N N 267 
PHE HD2  H N N 268 
PHE HE1  H N N 269 
PHE HE2  H N N 270 
PHE HZ   H N N 271 
PHE HXT  H N N 272 
PRO N    N N N 273 
PRO CA   C N S 274 
PRO C    C N N 275 
PRO O    O N N 276 
PRO CB   C N N 277 
PRO CG   C N N 278 
PRO CD   C N N 279 
PRO OXT  O N N 280 
PRO H    H N N 281 
PRO HA   H N N 282 
PRO HB2  H N N 283 
PRO HB3  H N N 284 
PRO HG2  H N N 285 
PRO HG3  H N N 286 
PRO HD2  H N N 287 
PRO HD3  H N N 288 
PRO HXT  H N N 289 
SER N    N N N 290 
SER CA   C N S 291 
SER C    C N N 292 
SER O    O N N 293 
SER CB   C N N 294 
SER OG   O N N 295 
SER OXT  O N N 296 
SER H    H N N 297 
SER H2   H N N 298 
SER HA   H N N 299 
SER HB2  H N N 300 
SER HB3  H N N 301 
SER HG   H N N 302 
SER HXT  H N N 303 
THR N    N N N 304 
THR CA   C N S 305 
THR C    C N N 306 
THR O    O N N 307 
THR CB   C N R 308 
THR OG1  O N N 309 
THR CG2  C N N 310 
THR OXT  O N N 311 
THR H    H N N 312 
THR H2   H N N 313 
THR HA   H N N 314 
THR HB   H N N 315 
THR HG1  H N N 316 
THR HG21 H N N 317 
THR HG22 H N N 318 
THR HG23 H N N 319 
THR HXT  H N N 320 
TRP N    N N N 321 
TRP CA   C N S 322 
TRP C    C N N 323 
TRP O    O N N 324 
TRP CB   C N N 325 
TRP CG   C Y N 326 
TRP CD1  C Y N 327 
TRP CD2  C Y N 328 
TRP NE1  N Y N 329 
TRP CE2  C Y N 330 
TRP CE3  C Y N 331 
TRP CZ2  C Y N 332 
TRP CZ3  C Y N 333 
TRP CH2  C Y N 334 
TRP OXT  O N N 335 
TRP H    H N N 336 
TRP H2   H N N 337 
TRP HA   H N N 338 
TRP HB2  H N N 339 
TRP HB3  H N N 340 
TRP HD1  H N N 341 
TRP HE1  H N N 342 
TRP HE3  H N N 343 
TRP HZ2  H N N 344 
TRP HZ3  H N N 345 
TRP HH2  H N N 346 
TRP HXT  H N N 347 
TYR N    N N N 348 
TYR CA   C N S 349 
TYR C    C N N 350 
TYR O    O N N 351 
TYR CB   C N N 352 
TYR CG   C Y N 353 
TYR CD1  C Y N 354 
TYR CD2  C Y N 355 
TYR CE1  C Y N 356 
TYR CE2  C Y N 357 
TYR CZ   C Y N 358 
TYR OH   O N N 359 
TYR OXT  O N N 360 
TYR H    H N N 361 
TYR H2   H N N 362 
TYR HA   H N N 363 
TYR HB2  H N N 364 
TYR HB3  H N N 365 
TYR HD1  H N N 366 
TYR HD2  H N N 367 
TYR HE1  H N N 368 
TYR HE2  H N N 369 
TYR HH   H N N 370 
TYR HXT  H N N 371 
VAL N    N N N 372 
VAL CA   C N S 373 
VAL C    C N N 374 
VAL O    O N N 375 
VAL CB   C N N 376 
VAL CG1  C N N 377 
VAL CG2  C N N 378 
VAL OXT  O N N 379 
VAL H    H N N 380 
VAL H2   H N N 381 
VAL HA   H N N 382 
VAL HB   H N N 383 
VAL HG11 H N N 384 
VAL HG12 H N N 385 
VAL HG13 H N N 386 
VAL HG21 H N N 387 
VAL HG22 H N N 388 
VAL HG23 H N N 389 
VAL HXT  H N N 390 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
PHE N   CA   sing N N 237 
PHE N   H    sing N N 238 
PHE N   H2   sing N N 239 
PHE CA  C    sing N N 240 
PHE CA  CB   sing N N 241 
PHE CA  HA   sing N N 242 
PHE C   O    doub N N 243 
PHE C   OXT  sing N N 244 
PHE CB  CG   sing N N 245 
PHE CB  HB2  sing N N 246 
PHE CB  HB3  sing N N 247 
PHE CG  CD1  doub Y N 248 
PHE CG  CD2  sing Y N 249 
PHE CD1 CE1  sing Y N 250 
PHE CD1 HD1  sing N N 251 
PHE CD2 CE2  doub Y N 252 
PHE CD2 HD2  sing N N 253 
PHE CE1 CZ   doub Y N 254 
PHE CE1 HE1  sing N N 255 
PHE CE2 CZ   sing Y N 256 
PHE CE2 HE2  sing N N 257 
PHE CZ  HZ   sing N N 258 
PHE OXT HXT  sing N N 259 
PRO N   CA   sing N N 260 
PRO N   CD   sing N N 261 
PRO N   H    sing N N 262 
PRO CA  C    sing N N 263 
PRO CA  CB   sing N N 264 
PRO CA  HA   sing N N 265 
PRO C   O    doub N N 266 
PRO C   OXT  sing N N 267 
PRO CB  CG   sing N N 268 
PRO CB  HB2  sing N N 269 
PRO CB  HB3  sing N N 270 
PRO CG  CD   sing N N 271 
PRO CG  HG2  sing N N 272 
PRO CG  HG3  sing N N 273 
PRO CD  HD2  sing N N 274 
PRO CD  HD3  sing N N 275 
PRO OXT HXT  sing N N 276 
SER N   CA   sing N N 277 
SER N   H    sing N N 278 
SER N   H2   sing N N 279 
SER CA  C    sing N N 280 
SER CA  CB   sing N N 281 
SER CA  HA   sing N N 282 
SER C   O    doub N N 283 
SER C   OXT  sing N N 284 
SER CB  OG   sing N N 285 
SER CB  HB2  sing N N 286 
SER CB  HB3  sing N N 287 
SER OG  HG   sing N N 288 
SER OXT HXT  sing N N 289 
THR N   CA   sing N N 290 
THR N   H    sing N N 291 
THR N   H2   sing N N 292 
THR CA  C    sing N N 293 
THR CA  CB   sing N N 294 
THR CA  HA   sing N N 295 
THR C   O    doub N N 296 
THR C   OXT  sing N N 297 
THR CB  OG1  sing N N 298 
THR CB  CG2  sing N N 299 
THR CB  HB   sing N N 300 
THR OG1 HG1  sing N N 301 
THR CG2 HG21 sing N N 302 
THR CG2 HG22 sing N N 303 
THR CG2 HG23 sing N N 304 
THR OXT HXT  sing N N 305 
TRP N   CA   sing N N 306 
TRP N   H    sing N N 307 
TRP N   H2   sing N N 308 
TRP CA  C    sing N N 309 
TRP CA  CB   sing N N 310 
TRP CA  HA   sing N N 311 
TRP C   O    doub N N 312 
TRP C   OXT  sing N N 313 
TRP CB  CG   sing N N 314 
TRP CB  HB2  sing N N 315 
TRP CB  HB3  sing N N 316 
TRP CG  CD1  doub Y N 317 
TRP CG  CD2  sing Y N 318 
TRP CD1 NE1  sing Y N 319 
TRP CD1 HD1  sing N N 320 
TRP CD2 CE2  doub Y N 321 
TRP CD2 CE3  sing Y N 322 
TRP NE1 CE2  sing Y N 323 
TRP NE1 HE1  sing N N 324 
TRP CE2 CZ2  sing Y N 325 
TRP CE3 CZ3  doub Y N 326 
TRP CE3 HE3  sing N N 327 
TRP CZ2 CH2  doub Y N 328 
TRP CZ2 HZ2  sing N N 329 
TRP CZ3 CH2  sing Y N 330 
TRP CZ3 HZ3  sing N N 331 
TRP CH2 HH2  sing N N 332 
TRP OXT HXT  sing N N 333 
TYR N   CA   sing N N 334 
TYR N   H    sing N N 335 
TYR N   H2   sing N N 336 
TYR CA  C    sing N N 337 
TYR CA  CB   sing N N 338 
TYR CA  HA   sing N N 339 
TYR C   O    doub N N 340 
TYR C   OXT  sing N N 341 
TYR CB  CG   sing N N 342 
TYR CB  HB2  sing N N 343 
TYR CB  HB3  sing N N 344 
TYR CG  CD1  doub Y N 345 
TYR CG  CD2  sing Y N 346 
TYR CD1 CE1  sing Y N 347 
TYR CD1 HD1  sing N N 348 
TYR CD2 CE2  doub Y N 349 
TYR CD2 HD2  sing N N 350 
TYR CE1 CZ   doub Y N 351 
TYR CE1 HE1  sing N N 352 
TYR CE2 CZ   sing Y N 353 
TYR CE2 HE2  sing N N 354 
TYR CZ  OH   sing N N 355 
TYR OH  HH   sing N N 356 
TYR OXT HXT  sing N N 357 
VAL N   CA   sing N N 358 
VAL N   H    sing N N 359 
VAL N   H2   sing N N 360 
VAL CA  C    sing N N 361 
VAL CA  CB   sing N N 362 
VAL CA  HA   sing N N 363 
VAL C   O    doub N N 364 
VAL C   OXT  sing N N 365 
VAL CB  CG1  sing N N 366 
VAL CB  CG2  sing N N 367 
VAL CB  HB   sing N N 368 
VAL CG1 HG11 sing N N 369 
VAL CG1 HG12 sing N N 370 
VAL CG1 HG13 sing N N 371 
VAL CG2 HG21 sing N N 372 
VAL CG2 HG22 sing N N 373 
VAL CG2 HG23 sing N N 374 
VAL OXT HXT  sing N N 375 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'Ministry of Education, Culture, Sports, Science and Technology (Japan)' Japan 18H05494                                 1 
'Japan Society for the Promotion of Science (JSPS)'                      Japan '23H00341, 19H03013, 18J01906, 15J10657' 2 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   5XCY 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 21 21 21' 
_space_group.name_Hall        'P 2ac 2ab' 
_space_group.IT_number        19 
_space_group.crystal_system   orthorhombic 
_space_group.id               1 
# 
_atom_sites.entry_id                    8W4Y 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.018067 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.014723 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.011137 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C   ? ? ? ? ? ? ? ? ? ? 6.64599990845  'Custom 0-Gaussian' ? 
D   ? ? ? ? ? ? ? ? ? ? 6.67100000381  'Custom 0-Gaussian' ? 
H   ? ? ? ? ? ? ? ? ? ? -3.73900008202 'Custom 0-Gaussian' ? 
N   ? ? ? ? ? ? ? ? ? ? 9.35999965668  'Custom 0-Gaussian' ? 
O   ? ? ? ? ? ? ? ? ? ? 5.8029999733   'Custom 0-Gaussian' ? 
O1- ? ? ? ? ? ? ? ? ? ? 5.8029999733   'Custom 0-Gaussian' ? 
S   ? ? ? ? ? ? ? ? ? ? 2.84699988365  'Custom 0-Gaussian' ? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N    A SER A 1 1   ? 29.28094  -26.60942 -22.33975 0.426 39.43986  ?  82  SER A N    1 
ATOM   2    N N    B SER A 1 1   ? 27.49660  -25.53793 -23.83701 0.574 42.39942  ?  82  SER A N    1 
ATOM   3    C CA   A SER A 1 1   ? 27.89276  -26.47323 -22.76867 0.426 39.24760  ?  82  SER A CA   1 
ATOM   4    C CA   B SER A 1 1   ? 28.23803  -26.66699 -23.26977 0.574 41.39588  ?  82  SER A CA   1 
ATOM   5    C C    A SER A 1 1   ? 27.16091  -27.81333 -22.83172 0.426 35.72077  ?  82  SER A C    1 
ATOM   6    C C    B SER A 1 1   ? 27.31511  -27.88056 -23.06568 0.574 36.50049  ?  82  SER A C    1 
ATOM   7    O O    A SER A 1 1   ? 26.04284  -27.90189 -23.35893 0.426 35.19573  ?  82  SER A O    1 
ATOM   8    O O    B SER A 1 1   ? 26.20403  -27.93468 -23.61017 0.574 35.88922  ?  82  SER A O    1 
ATOM   9    C CB   A SER A 1 1   ? 27.81952  -25.79204 -24.14997 0.426 41.20353  ?  82  SER A CB   1 
ATOM   10   C CB   B SER A 1 1   ? 28.95193  -26.26787 -21.96366 0.574 35.64861  ?  82  SER A CB   1 
ATOM   11   O OG   A SER A 1 1   ? 26.49151  -25.80060 -24.64729 0.426 35.98645  ?  82  SER A OG   1 
ATOM   12   O OG   B SER A 1 1   ? 28.05732  -25.79459 -20.97840 0.574 33.68514  ?  82  SER A OG   1 
ATOM   13   H HA   A SER A 1 1   ? 27.38080  -25.85369 -22.03235 0.426 47.09712  ?  82  SER A HA   1 
ATOM   14   H HA   B SER A 1 1   ? 29.02065  -26.96785 -23.96625 0.574 49.67506  ?  82  SER A HA   1 
ATOM   15   H HB2  A SER A 1 1   ? 28.15602  -24.75967 -24.05471 0.426 49.44423  ?  82  SER A HB2  1 
ATOM   16   H HB2  B SER A 1 1   ? 29.46996  -27.14253 -21.57032 0.574 42.77833  ?  82  SER A HB2  1 
ATOM   17   H HB3  A SER A 1 1   ? 28.46243  -26.33100 -24.84587 0.426 49.44423  ?  82  SER A HB3  1 
ATOM   18   H HB3  B SER A 1 1   ? 29.66985  -25.47895 -22.18794 0.574 42.77833  ?  82  SER A HB3  1 
ATOM   19   N N    . ALA A 1 2   ? 27.78953  -28.86204 -22.29195 1.000 23.73527  ?  83  ALA A N    1 
ATOM   20   C CA   . ALA A 1 2   ? 27.09944  -30.13764 -22.24263 1.000 17.87154  ?  83  ALA A CA   1 
ATOM   21   C C    A ALA A 1 2   ? 25.86002  -30.06714 -21.36030 0.490 18.25978  ?  83  ALA A C    1 
ATOM   22   C C    B ALA A 1 2   ? 25.85975  -30.06807 -21.35787 0.510 18.24782  ?  83  ALA A C    1 
ATOM   23   O O    . ALA A 1 2   ? 24.89502  -30.80326 -21.59121 1.000 21.72412  ?  83  ALA A O    1 
ATOM   24   C CB   A ALA A 1 2   ? 28.04522  -31.21267 -21.71825 0.490 22.17989  ?  83  ALA A CB   1 
ATOM   25   C CB   B ALA A 1 2   ? 28.04327  -31.20976 -21.70769 0.510 22.17386  ?  83  ALA A CB   1 
ATOM   26   H H    A ALA A 1 2   ? 28.73156  -28.85377 -21.90090 0.684 28.48233  ?  83  ALA A H    1 
ATOM   27   D D    B ALA A 1 2   ? 28.62363  -28.80101 -21.70803 0.316 28.48233  ?  83  ALA A D    1 
ATOM   28   H HA   A ALA A 1 2   ? 26.78710  -30.40942 -23.25094 0.490 21.44585  ?  83  ALA A HA   1 
ATOM   29   H HA   B ALA A 1 2   ? 26.79197  -30.41711 -23.25033 0.510 21.44585  ?  83  ALA A HA   1 
ATOM   30   H HB1  A ALA A 1 2   ? 27.97698  -32.08989 -22.36162 0.490 26.61586  ?  83  ALA A HB1  1 
ATOM   31   H HB1  B ALA A 1 2   ? 27.75141  -31.46301 -20.68849 0.510 26.60863  ?  83  ALA A HB1  1 
ATOM   32   H HB2  A ALA A 1 2   ? 29.06356  -30.82408 -21.72637 0.490 26.61586  ?  83  ALA A HB2  1 
ATOM   33   H HB2  B ALA A 1 2   ? 27.97507  -32.09214 -22.34399 0.510 26.60863  ?  83  ALA A HB2  1 
ATOM   34   H HB3  A ALA A 1 2   ? 27.75543  -31.47460 -20.70065 0.490 26.61586  ?  83  ALA A HB3  1 
ATOM   35   H HB3  B ALA A 1 2   ? 29.06210  -30.82247 -21.71723 0.510 26.60863  ?  83  ALA A HB3  1 
ATOM   36   N N    . ASN A 1 3   ? 25.86620  -29.19250 -20.35276 1.000 16.91519  ?  84  ASN A N    1 
ATOM   37   C CA   . ASN A 1 3   ? 24.79906  -29.08999 -19.37222 1.000 16.34886  ?  84  ASN A CA   1 
ATOM   38   C C    . ASN A 1 3   ? 24.03358  -27.79672 -19.64272 1.000 16.63342  ?  84  ASN A C    1 
ATOM   39   O O    . ASN A 1 3   ? 24.44779  -26.72584 -19.20665 1.000 23.97015  ?  84  ASN A O    1 
ATOM   40   C CB   . ASN A 1 3   ? 25.43750  -29.05966 -17.99138 1.000 17.25391  ?  84  ASN A CB   1 
ATOM   41   C CG   . ASN A 1 3   ? 24.43229  -28.96079 -16.89517 1.000 28.04276  ?  84  ASN A CG   1 
ATOM   42   O OD1  . ASN A 1 3   ? 23.34218  -29.50789 -16.99549 1.000 26.28487  ?  84  ASN A OD1  1 
ATOM   43   N ND2  . ASN A 1 3   ? 24.78531  -28.24801 -15.83195 1.000 28.78018  ?  84  ASN A ND2  1 
ATOM   44   H H    A ASN A 1 3   ? 26.62163  -28.52632 -20.19168 0.942 20.29823  ?  84  ASN A H    1 
ATOM   45   D D    B ASN A 1 3   ? 26.62247  -28.52643 -20.19526 0.058 20.29823  ?  84  ASN A D    1 
ATOM   46   H HA   . ASN A 1 3   ? 24.10037  -29.92190 -19.46091 1.000 19.61863  ?  84  ASN A HA   1 
ATOM   47   H HB2  . ASN A 1 3   ? 26.00874  -29.97615 -17.84363 1.000 20.70469  ?  84  ASN A HB2  1 
ATOM   48   H HB3  . ASN A 1 3   ? 26.09686  -28.19436 -17.92352 1.000 20.70469  ?  84  ASN A HB3  1 
ATOM   49   N N    . ASN A 1 4   ? 22.93754  -27.90988 -20.32958 1.000 13.53839  ?  85  ASN A N    1 
ATOM   50   C CA   . ASN A 1 4   ? 21.99219  -26.79141 -20.46812 1.000 14.12536  ?  85  ASN A CA   1 
ATOM   51   C C    . ASN A 1 4   ? 20.97497  -26.90140 -19.34211 1.000 13.63833  ?  85  ASN A C    1 
ATOM   52   O O    . ASN A 1 4   ? 20.29556  -27.92170 -19.25198 1.000 13.42400  ?  85  ASN A O    1 
ATOM   53   C CB   . ASN A 1 4   ? 21.27821  -26.88132 -21.80408 1.000 13.97978  ?  85  ASN A CB   1 
ATOM   54   C CG   . ASN A 1 4   ? 20.37610  -25.69335 -22.06139 1.000 14.80764  ?  85  ASN A CG   1 
ATOM   55   O OD1  . ASN A 1 4   ? 19.68785  -25.24744 -21.14782 1.000 16.26978  ?  85  ASN A OD1  1 
ATOM   56   N ND2  . ASN A 1 4   ? 20.34734  -25.18850 -23.27195 1.000 14.31302  ?  85  ASN A ND2  1 
ATOM   57   H H    A ASN A 1 4   ? 22.64920  -28.75878 -20.81602 0.623 16.24606  ?  85  ASN A H    1 
ATOM   58   D D    B ASN A 1 4   ? 22.64906  -28.75870 -20.81608 0.377 16.24606  ?  85  ASN A D    1 
ATOM   59   H HA   . ASN A 1 4   ? 22.50613  -25.83192 -20.41019 1.000 16.95043  ?  85  ASN A HA   1 
ATOM   60   H HB2  . ASN A 1 4   ? 22.01963  -26.92183 -22.60204 1.000 16.77573  ?  85  ASN A HB2  1 
ATOM   61   H HB3  . ASN A 1 4   ? 20.66410  -27.78173 -21.81973 1.000 16.77573  ?  85  ASN A HB3  1 
ATOM   62   N N    . PRO A 1 5   ? 20.86214  -25.91155 -18.45217 1.000 12.91046  ?  86  PRO A N    1 
ATOM   63   C CA   . PRO A 1 5   ? 19.99497  -26.08428 -17.27912 1.000 14.21268  ?  86  PRO A CA   1 
ATOM   64   C C    . PRO A 1 5   ? 18.54407  -26.37889 -17.60011 1.000 12.82920  ?  86  PRO A C    1 
ATOM   65   O O    . PRO A 1 5   ? 17.84824  -26.95367 -16.74534 1.000 13.56571  ?  86  PRO A O    1 
ATOM   66   C CB   . PRO A 1 5   ? 20.14205  -24.73470 -16.51767 1.000 13.79762  ?  86  PRO A CB   1 
ATOM   67   C CG   . PRO A 1 5   ? 21.40925  -24.16649 -16.97239 1.000 15.05070  ?  86  PRO A CG   1 
ATOM   68   C CD   . PRO A 1 5   ? 21.56000  -24.60267 -18.41066 1.000 13.59391  ?  86  PRO A CD   1 
ATOM   69   H HA   . PRO A 1 5   ? 20.38676  -26.89507 -16.66494 1.000 17.05522  ?  86  PRO A HA   1 
ATOM   70   H HB2  . PRO A 1 5   ? 19.30966  -24.07716 -16.76840 1.000 16.55715  ?  86  PRO A HB2  1 
ATOM   71   H HB3  . PRO A 1 5   ? 20.16205  -24.91770 -15.44332 1.000 16.55715  ?  86  PRO A HB3  1 
ATOM   72   H HG2  . PRO A 1 5   ? 21.37268  -23.07952 -16.89977 1.000 18.06084  ?  86  PRO A HG2  1 
ATOM   73   H HG3  . PRO A 1 5   ? 22.22614  -24.55354 -16.36330 1.000 18.06084  ?  86  PRO A HG3  1 
ATOM   74   H HD2  . PRO A 1 5   ? 21.08405  -23.88904 -19.08320 1.000 16.31269  ?  86  PRO A HD2  1 
ATOM   75   H HD3  . PRO A 1 5   ? 22.61203  -24.71676 -18.67203 1.000 16.31269  ?  86  PRO A HD3  1 
ATOM   76   N N    . TRP A 1 6   ? 18.05990  -26.02281 -18.76856 1.000 12.78319  ?  87  TRP A N    1 
ATOM   77   C CA   . TRP A 1 6   ? 16.65256  -26.22089 -19.12445 1.000 12.08330  ?  87  TRP A CA   1 
ATOM   78   C C    . TRP A 1 6   ? 16.33601  -27.59850 -19.68084 1.000 14.48605  ?  87  TRP A C    1 
ATOM   79   O O    . TRP A 1 6   ? 15.17280  -28.00786 -19.64744 1.000 16.35301  ?  87  TRP A O    1 
ATOM   80   C CB   . TRP A 1 6   ? 16.19533  -25.16177 -20.13064 1.000 13.01972  ?  87  TRP A CB   1 
ATOM   81   C CG   . TRP A 1 6   ? 15.89369  -23.84130 -19.49029 1.000 10.47538  ?  87  TRP A CG   1 
ATOM   82   C CD1  . TRP A 1 6   ? 14.68086  -23.45726 -18.98647 1.000 11.82496  ?  87  TRP A CD1  1 
ATOM   83   C CD2  . TRP A 1 6   ? 16.80496  -22.76979 -19.22553 1.000 10.55773  ?  87  TRP A CD2  1 
ATOM   84   N NE1  . TRP A 1 6   ? 14.79254  -22.22627 -18.45222 1.000 13.50137  ?  87  TRP A NE1  1 
ATOM   85   C CE2  . TRP A 1 6   ? 16.07401  -21.76524 -18.58316 1.000 11.86235  ?  87  TRP A CE2  1 
ATOM   86   C CE3  . TRP A 1 6   ? 18.17117  -22.56113 -19.48312 1.000 12.64742  ?  87  TRP A CE3  1 
ATOM   87   C CZ2  . TRP A 1 6   ? 16.65652  -20.56032 -18.18185 1.000 13.28527  ?  87  TRP A CZ2  1 
ATOM   88   C CZ3  . TRP A 1 6   ? 18.74380  -21.38069 -19.07433 1.000 11.49354  ?  87  TRP A CZ3  1 
ATOM   89   C CH2  . TRP A 1 6   ? 17.98246  -20.38888 -18.43548 1.000 12.67729  ?  87  TRP A CH2  1 
ATOM   90   H H    A TRP A 1 6   ? 18.61215  -25.58854 -19.50803 0.990 15.33983  ?  87  TRP A H    1 
ATOM   91   D D    B TRP A 1 6   ? 18.61209  -25.58853 -19.50808 0.010 15.33983  ?  87  TRP A D    1 
ATOM   92   H HA   . TRP A 1 6   ? 16.06775  -26.09867 -18.21277 1.000 14.49996  ?  87  TRP A HA   1 
ATOM   93   H HB2  . TRP A 1 6   ? 16.98523  -25.00698 -20.86562 1.000 15.62366  ?  87  TRP A HB2  1 
ATOM   94   H HB3  . TRP A 1 6   ? 15.28901  -25.51097 -20.62535 1.000 15.62366  ?  87  TRP A HB3  1 
ATOM   95   H HD1  . TRP A 1 6   ? 13.77709  -24.04793 -19.01309 1.000 14.18996  ?  87  TRP A HD1  1 
ATOM   96   H HE3  . TRP A 1 6   ? 18.75788  -23.31216 -19.99118 1.000 15.17690  ?  87  TRP A HE3  1 
ATOM   97   H HZ2  . TRP A 1 6   ? 16.07647  -19.79410 -17.68906 1.000 15.94232  ?  87  TRP A HZ2  1 
ATOM   98   H HZ3  . TRP A 1 6   ? 19.79661  -21.21312 -19.24728 1.000 13.79225  ?  87  TRP A HZ3  1 
ATOM   99   H HH2  . TRP A 1 6   ? 18.46086  -19.46741 -18.13811 1.000 15.21274  ?  87  TRP A HH2  1 
ATOM   100  N N    . THR A 1 7   ? 17.33389  -28.35753 -20.13874 1.000 14.29167  ?  88  THR A N    1 
ATOM   101  C CA   . THR A 1 7   ? 17.06068  -29.62632 -20.79807 1.000 16.24425  ?  88  THR A CA   1 
ATOM   102  C C    . THR A 1 7   ? 16.45143  -30.60161 -19.79644 1.000 15.28558  ?  88  THR A C    1 
ATOM   103  O O    . THR A 1 7   ? 17.00831  -30.83989 -18.71487 1.000 16.51822  ?  88  THR A O    1 
ATOM   104  C CB   . THR A 1 7   ? 18.35902  -30.21648 -21.37479 1.000 18.46558  ?  88  THR A CB   1 
ATOM   105  O OG1  . THR A 1 7   ? 18.88257  -29.28840 -22.31528 1.000 22.51373  ?  88  THR A OG1  1 
ATOM   106  C CG2  . THR A 1 7   ? 18.07460  -31.55379 -22.06488 1.000 21.61701  ?  88  THR A CG2  1 
ATOM   107  H H    A THR A 1 7   ? 18.32377  -28.12195 -20.06764 0.639 17.15001  ?  88  THR A H    1 
ATOM   108  D D    B THR A 1 7   ? 18.32410  -28.12314 -20.06829 0.361 17.15001  ?  88  THR A D    1 
ATOM   109  H HA   . THR A 1 7   ? 16.35966  -29.47005 -21.61798 1.000 19.49310  ?  88  THR A HA   1 
ATOM   110  H HB   . THR A 1 7   ? 19.08683  -30.40045 -20.58450 1.000 22.15869  ?  88  THR A HB   1 
ATOM   111  H HG21 . THR A 1 7   ? 19.00266  -32.11001 -22.19687 1.000 25.94041  ?  88  THR A HG21 1 
ATOM   112  H HG22 . THR A 1 7   ? 17.38948  -32.14737 -21.45959 1.000 25.94041  ?  88  THR A HG22 1 
ATOM   113  H HG23 . THR A 1 7   ? 17.62394  -31.38060 -23.04213 1.000 25.94041  ?  88  THR A HG23 1 
ATOM   114  N N    . GLY A 1 8   ? 15.30697  -31.17895 -20.19535 1.000 16.32384  ?  89  GLY A N    1 
ATOM   115  C CA   . GLY A 1 8   ? 14.65428  -32.19248 -19.37543 1.000 20.49101  ?  89  GLY A CA   1 
ATOM   116  C C    . GLY A 1 8   ? 13.76778  -31.66162 -18.28412 1.000 20.63199  ?  89  GLY A C    1 
ATOM   117  O O    . GLY A 1 8   ? 13.30297  -32.45348 -17.45444 1.000 23.01576  ?  89  GLY A O    1 
ATOM   118  H H    A GLY A 1 8   ? 14.82246  -30.96432 -21.06690 0.502 19.58861  ?  89  GLY A H    1 
ATOM   119  D D    B GLY A 1 8   ? 14.82224  -30.96453 -21.06682 0.498 19.58861  ?  89  GLY A D    1 
ATOM   120  H HA2  . GLY A 1 8   ? 14.04195  -32.82077 -20.02228 1.000 24.58921  ?  89  GLY A HA2  1 
ATOM   121  H HA3  . GLY A 1 8   ? 15.42257  -32.80772 -18.90713 1.000 24.58921  ?  89  GLY A HA3  1 
ATOM   122  N N    . PHE A 1 9   ? 13.53818  -30.35685 -18.24082 1.000 15.30395  ?  90  PHE A N    1 
ATOM   123  C CA   . PHE A 1 9   ? 12.70797  -29.75371 -17.20487 1.000 14.78649  ?  90  PHE A CA   1 
ATOM   124  C C    . PHE A 1 9   ? 11.52457  -29.04059 -17.81616 1.000 13.70212  ?  90  PHE A C    1 
ATOM   125  O O    . PHE A 1 9   ? 11.55477  -28.59732 -18.96281 1.000 16.74882  ?  90  PHE A O    1 
ATOM   126  C CB   . PHE A 1 9   ? 13.50342  -28.71501 -16.40250 1.000 14.52627  ?  90  PHE A CB   1 
ATOM   127  C CG   . PHE A 1 9   ? 14.45565  -29.34345 -15.43386 1.000 17.23059  ?  90  PHE A CG   1 
ATOM   128  C CD1  . PHE A 1 9   ? 15.65611  -29.86617 -15.88421 1.000 18.91862  ?  90  PHE A CD1  1 
ATOM   129  C CD2  . PHE A 1 9   ? 14.14288  -29.43940 -14.08718 1.000 16.43068  ?  90  PHE A CD2  1 
ATOM   130  C CE1  . PHE A 1 9   ? 16.53422  -30.45942 -14.98154 1.000 20.48081  ?  90  PHE A CE1  1 
ATOM   131  C CE2  . PHE A 1 9   ? 15.00139  -30.03144 -13.18869 1.000 16.73850  ?  90  PHE A CE2  1 
ATOM   132  C CZ   . PHE A 1 9   ? 16.19735  -30.55357 -13.63573 1.000 20.97347  ?  90  PHE A CZ   1 
ATOM   133  H H    A PHE A 1 9   ? 13.91469  -29.68752 -18.91212 0.598 18.36474  ?  90  PHE A H    1 
ATOM   134  D D    B PHE A 1 9   ? 13.91562  -29.68904 -18.91310 0.402 18.36474  ?  90  PHE A D    1 
ATOM   135  H HA   . PHE A 1 9   ? 12.34846  -30.54614 -16.54843 1.000 17.74378  ?  90  PHE A HA   1 
ATOM   136  H HB2  . PHE A 1 9   ? 14.08003  -28.09851 -17.09209 1.000 17.43152  ?  90  PHE A HB2  1 
ATOM   137  H HB3  . PHE A 1 9   ? 12.80835  -28.09308 -15.83841 1.000 17.43152  ?  90  PHE A HB3  1 
ATOM   138  H HD1  . PHE A 1 9   ? 15.91041  -29.81380 -16.93253 1.000 22.70234  ?  90  PHE A HD1  1 
ATOM   139  H HD2  . PHE A 1 9   ? 13.20342  -29.04025 -13.73433 1.000 19.71681  ?  90  PHE A HD2  1 
ATOM   140  H HE1  . PHE A 1 9   ? 17.48056  -30.84797 -15.32775 1.000 24.57697  ?  90  PHE A HE1  1 
ATOM   141  H HE2  . PHE A 1 9   ? 14.74066  -30.08672 -12.14209 1.000 20.08620  ?  90  PHE A HE2  1 
ATOM   142  H HZ   . PHE A 1 9   ? 16.87078  -31.03456 -12.94180 1.000 25.16817  ?  90  PHE A HZ   1 
ATOM   143  N N    . GLN A 1 10  ? 10.46202  -28.96501 -17.03956 1.000 14.59721  ?  91  GLN A N    1 
ATOM   144  C CA   A GLN A 1 10  ? 9.31145   -28.14172 -17.37769 0.567 14.87726  ?  91  GLN A CA   1 
ATOM   145  C CA   B GLN A 1 10  ? 9.31374   -28.13931 -17.37490 0.433 14.80971  ?  91  GLN A CA   1 
ATOM   146  C C    . GLN A 1 10  ? 9.44302   -26.84847 -16.58403 1.000 12.13554  ?  91  GLN A C    1 
ATOM   147  O O    . GLN A 1 10  ? 9.83117   -26.87538 -15.42600 1.000 16.31234  ?  91  GLN A O    1 
ATOM   148  C CB   A GLN A 1 10  ? 7.99147   -28.83293 -17.01598 0.567 16.09570  ?  91  GLN A CB   1 
ATOM   149  C CB   B GLN A 1 10  ? 8.01809   -28.86268 -17.00459 0.433 16.13522  ?  91  GLN A CB   1 
ATOM   150  C CG   A GLN A 1 10  ? 7.74127   -30.13500 -17.75393 0.567 23.46779  ?  91  GLN A CG   1 
ATOM   151  C CG   B GLN A 1 10  ? 6.77084   -28.21022 -17.53390 0.433 25.11553  ?  91  GLN A CG   1 
ATOM   152  C CD   A GLN A 1 10  ? 7.39340   -29.94415 -19.21536 0.567 27.71165  ?  91  GLN A CD   1 
ATOM   153  C CD   B GLN A 1 10  ? 5.54909   -29.07058 -17.30274 0.433 29.64336  ?  91  GLN A CD   1 
ATOM   154  O OE1  A GLN A 1 10  ? 7.13193   -28.83286 -19.67154 0.567 33.56350  ?  91  GLN A OE1  1 
ATOM   155  O OE1  B GLN A 1 10  ? 4.62147   -28.68686 -16.58321 0.433 27.04625  ?  91  GLN A OE1  1 
ATOM   156  N NE2  A GLN A 1 10  ? 7.38458   -31.04356 -19.96447 0.567 43.54513  ?  91  GLN A NE2  1 
ATOM   157  N NE2  B GLN A 1 10  ? 5.55104   -30.25907 -17.90448 0.433 35.60834  ?  91  GLN A NE2  1 
ATOM   158  H H    A GLN A 1 10  ? 10.36344  -29.46745 -16.15738 0.677 17.51665  ?  91  GLN A H    1 
ATOM   159  D D    B GLN A 1 10  ? 10.36401  -29.47042 -16.15902 0.323 17.51665  ?  91  GLN A D    1 
ATOM   160  H HA   A GLN A 1 10  ? 9.28151   -27.94194 -18.44881 0.567 17.85271  ?  91  GLN A HA   1 
ATOM   161  H HA   B GLN A 1 10  ? 9.27177   -27.91568 -18.44089 0.433 17.77166  ?  91  GLN A HA   1 
ATOM   162  H HB2  A GLN A 1 10  ? 7.99669   -29.05486 -15.94883 0.567 19.31484  ?  91  GLN A HB2  1 
ATOM   163  H HB2  B GLN A 1 10  ? 8.05745   -29.87475 -17.40740 0.433 19.36227  ?  91  GLN A HB2  1 
ATOM   164  H HB3  A GLN A 1 10  ? 7.16947   -28.15721 -17.25222 0.567 19.31484  ?  91  GLN A HB3  1 
ATOM   165  H HB3  B GLN A 1 10  ? 7.93706   -28.89674 -15.91814 0.433 19.36227  ?  91  GLN A HB3  1 
ATOM   166  H HG2  A GLN A 1 10  ? 8.64170   -30.74714 -17.70274 0.567 28.16135  ?  91  GLN A HG2  1 
ATOM   167  H HG2  B GLN A 1 10  ? 6.61967   -27.25775 -17.02592 0.433 30.13864  ?  91  GLN A HG2  1 
ATOM   168  H HG3  A GLN A 1 10  ? 6.90956   -30.65481 -17.27837 0.567 28.16135  ?  91  GLN A HG3  1 
ATOM   169  H HG3  B GLN A 1 10  ? 6.87707   -28.04795 -18.60651 0.433 30.13864  ?  91  GLN A HG3  1 
ATOM   170  N N    . ILE A 1 11  ? 9.14730   -25.73287 -17.21230 1.000 13.29371  ?  92  ILE A N    1 
ATOM   171  C CA   . ILE A 1 11  ? 9.27690   -24.43465 -16.55710 1.000 12.88449  ?  92  ILE A CA   1 
ATOM   172  C C    . ILE A 1 11  ? 7.98506   -24.13146 -15.81368 1.000 12.98942  ?  92  ILE A C    1 
ATOM   173  O O    . ILE A 1 11  ? 6.89972   -24.16103 -16.39840 1.000 14.64835  ?  92  ILE A O    1 
ATOM   174  C CB   . ILE A 1 11  ? 9.62855   -23.32001 -17.54739 1.000 12.24788  ?  92  ILE A CB   1 
ATOM   175  C CG1  . ILE A 1 11  ? 10.92204  -23.67393 -18.28768 1.000 15.65180  ?  92  ILE A CG1  1 
ATOM   176  C CG2  . ILE A 1 11  ? 9.76356   -22.01719 -16.77285 1.000 14.98624  ?  92  ILE A CG2  1 
ATOM   177  C CD1  . ILE A 1 11  ? 11.14820  -22.75859 -19.47135 1.000 20.19597  ?  92  ILE A CD1  1 
ATOM   178  H H    A ILE A 1 11  ? 8.81473   -25.68521 -18.17538 0.709 15.95245  ?  92  ILE A H    1 
ATOM   179  D D    B ILE A 1 11  ? 8.81479   -25.68643 -18.17546 0.291 15.95245  ?  92  ILE A D    1 
ATOM   180  H HA   . ILE A 1 11  ? 10.08913  -24.49040 -15.83235 1.000 15.46138  ?  92  ILE A HA   1 
ATOM   181  H HB   . ILE A 1 11  ? 8.84362   -23.20889 -18.29548 1.000 14.69745  ?  92  ILE A HB   1 
ATOM   182  H HG12 . ILE A 1 11  ? 11.76706  -23.57108 -17.60689 1.000 18.78216  ?  92  ILE A HG12 1 
ATOM   183  H HG13 . ILE A 1 11  ? 10.85993  -24.69916 -18.65257 1.000 18.78216  ?  92  ILE A HG13 1 
ATOM   184  H HG21 . ILE A 1 11  ? 10.32624  -22.20470 -15.85834 1.000 17.98349  ?  92  ILE A HG21 1 
ATOM   185  H HG22 . ILE A 1 11  ? 10.29019  -21.28991 -17.39077 1.000 17.98349  ?  92  ILE A HG22 1 
ATOM   186  H HG23 . ILE A 1 11  ? 8.76870   -21.64545 -16.52754 1.000 17.98349  ?  92  ILE A HG23 1 
ATOM   187  H HD11 . ILE A 1 11  ? 10.62432  -21.81855 -19.29819 1.000 24.23516  ?  92  ILE A HD11 1 
ATOM   188  H HD12 . ILE A 1 11  ? 12.21716  -22.57418 -19.57820 1.000 24.23516  ?  92  ILE A HD12 1 
ATOM   189  H HD13 . ILE A 1 11  ? 10.76222  -23.23909 -20.37037 1.000 24.23516  ?  92  ILE A HD13 1 
ATOM   190  N N    . PHE A 1 12  ? 8.09670   -23.84304 -14.52711 1.000 12.13501  ?  93  PHE A N    1 
ATOM   191  C CA   . PHE A 1 12  ? 6.95837   -23.42012 -13.73094 1.000 11.78870  ?  93  PHE A CA   1 
ATOM   192  C C    . PHE A 1 12  ? 6.51118   -22.04718 -14.17859 1.000 14.21230  ?  93  PHE A C    1 
ATOM   193  O O    . PHE A 1 12  ? 7.29185   -21.09966 -14.24827 1.000 14.68287  ?  93  PHE A O    1 
ATOM   194  C CB   . PHE A 1 12  ? 7.38416   -23.36339 -12.24835 1.000 13.65150  ?  93  PHE A CB   1 
ATOM   195  C CG   . PHE A 1 12  ? 6.27695   -22.97061 -11.31204 1.000 14.98495  ?  93  PHE A CG   1 
ATOM   196  C CD1  . PHE A 1 12  ? 5.25110   -23.84106 -11.07383 1.000 19.09832  ?  93  PHE A CD1  1 
ATOM   197  C CD2  . PHE A 1 12  ? 6.29262   -21.74610 -10.67349 1.000 17.18293  ?  93  PHE A CD2  1 
ATOM   198  C CE1  . PHE A 1 12  ? 4.21204   -23.47670 -10.18462 1.000 20.49211  ?  93  PHE A CE1  1 
ATOM   199  C CE2  . PHE A 1 12  ? 5.26896   -21.39597 -9.77831  1.000 19.14576  ?  93  PHE A CE2  1 
ATOM   200  C CZ   . PHE A 1 12  ? 4.25823   -22.27416 -9.55836  1.000 17.26513  ?  93  PHE A CZ   1 
ATOM   201  H H    A PHE A 1 12  ? 8.96935   -23.89260 -14.00135 0.983 14.56201  ?  93  PHE A H    1 
ATOM   202  D D    B PHE A 1 12  ? 8.96866   -23.89218 -14.00017 0.017 14.56201  ?  93  PHE A D    1 
ATOM   203  H HA   . PHE A 1 12  ? 6.12929   -24.11809 -13.84743 1.000 14.14644  ?  93  PHE A HA   1 
ATOM   204  H HB2  . PHE A 1 12  ? 7.73874   -24.34943 -11.94817 1.000 16.38180  ?  93  PHE A HB2  1 
ATOM   205  H HB3  . PHE A 1 12  ? 8.18447   -22.63109 -12.14193 1.000 16.38180  ?  93  PHE A HB3  1 
ATOM   206  H HD1  . PHE A 1 12  ? 5.23316   -24.80401 -11.56250 1.000 22.91798  ?  93  PHE A HD1  1 
ATOM   207  H HD2  . PHE A 1 12  ? 7.09828   -21.05258 -10.86410 1.000 20.61951  ?  93  PHE A HD2  1 
ATOM   208  H HE1  . PHE A 1 12  ? 3.38794   -24.15145 -10.00584 1.000 24.59054  ?  93  PHE A HE1  1 
ATOM   209  H HE2  . PHE A 1 12  ? 5.28587   -20.44193 -9.27242  1.000 22.97492  ?  93  PHE A HE2  1 
ATOM   210  H HZ   . PHE A 1 12  ? 3.47122   -22.00931 -8.86780  1.000 20.71815  ?  93  PHE A HZ   1 
ATOM   211  N N    . LEU A 1 13  ? 5.23303   -21.90908 -14.46624 1.000 12.54102  ?  94  LEU A N    1 
ATOM   212  C CA   . LEU A 1 13  ? 4.67421   -20.65053 -14.94581 1.000 13.56633  ?  94  LEU A CA   1 
ATOM   213  C C    . LEU A 1 13  ? 4.31195   -19.73946 -13.78744 1.000 15.00681  ?  94  LEU A C    1 
ATOM   214  O O    . LEU A 1 13  ? 3.59929   -20.14397 -12.86293 1.000 18.70355  ?  94  LEU A O    1 
ATOM   215  C CB   . LEU A 1 13  ? 3.42038   -20.91621 -15.77993 1.000 15.21273  ?  94  LEU A CB   1 
ATOM   216  C CG   . LEU A 1 13  ? 3.66631   -21.65477 -17.09100 1.000 15.73359  ?  94  LEU A CG   1 
ATOM   217  C CD1  . LEU A 1 13  ? 2.29912   -22.05761 -17.70837 1.000 21.18036  ?  94  LEU A CD1  1 
ATOM   218  C CD2  . LEU A 1 13  ? 4.48040   -20.85201 -18.05755 1.000 17.10056  ?  94  LEU A CD2  1 
ATOM   219  H H    A LEU A 1 13  ? 4.54440   -22.65641 -14.37856 0.788 15.04923  ?  94  LEU A H    1 
ATOM   220  D D    B LEU A 1 13  ? 4.54505   -22.65698 -14.37827 0.212 15.04923  ?  94  LEU A D    1 
ATOM   221  H HA   . LEU A 1 13  ? 5.42587   -20.14770 -15.55432 1.000 16.27960  ?  94  LEU A HA   1 
ATOM   222  H HB2  . LEU A 1 13  ? 2.73355   -21.52019 -15.18700 1.000 18.25528  ?  94  LEU A HB2  1 
ATOM   223  H HB3  . LEU A 1 13  ? 2.95958   -19.95904 -16.02404 1.000 18.25528  ?  94  LEU A HB3  1 
ATOM   224  H HG   . LEU A 1 13  ? 4.25095   -22.55176 -16.88676 1.000 18.88031  ?  94  LEU A HG   1 
ATOM   225  H HD11 . LEU A 1 13  ? 2.42507   -22.21078 -18.78018 1.000 25.41643  ?  94  LEU A HD11 1 
ATOM   226  H HD12 . LEU A 1 13  ? 1.95561   -22.97944 -17.23898 1.000 25.41643  ?  94  LEU A HD12 1 
ATOM   227  H HD13 . LEU A 1 13  ? 1.57960   -21.25870 -17.52908 1.000 25.41643  ?  94  LEU A HD13 1 
ATOM   228  H HD21 . LEU A 1 13  ? 4.09489   -19.83285 -18.08546 1.000 20.52067  ?  94  LEU A HD21 1 
ATOM   229  H HD22 . LEU A 1 13  ? 5.51947   -20.84749 -17.72829 1.000 20.52067  ?  94  LEU A HD22 1 
ATOM   230  H HD23 . LEU A 1 13  ? 4.40574   -21.30487 -19.04621 1.000 20.52067  ?  94  LEU A HD23 1 
ATOM   231  N N    . SER A 1 14  ? 4.78251   -18.50682 -13.85330 1.000 15.18333  ?  95  SER A N    1 
ATOM   232  C CA   . SER A 1 14  ? 4.57443   -17.57055 -12.75916 1.000 16.43770  ?  95  SER A CA   1 
ATOM   233  C C    . SER A 1 14  ? 3.09504   -17.37112 -12.48665 1.000 18.65592  ?  95  SER A C    1 
ATOM   234  O O    . SER A 1 14  ? 2.36841   -16.91678 -13.37705 1.000 16.81978  ?  95  SER A O    1 
ATOM   235  C CB   . SER A 1 14  ? 5.16229   -16.22530 -13.12489 1.000 17.59506  ?  95  SER A CB   1 
ATOM   236  O OG   . SER A 1 14  ? 4.67115   -15.23771 -12.19815 1.000 22.89975  ?  95  SER A OG   1 
ATOM   237  H H    A SER A 1 14  ? 5.30700   -18.12692 -14.64133 0.727 18.22000  ?  95  SER A H    1 
ATOM   238  D D    B SER A 1 14  ? 5.30705   -18.12635 -14.64102 0.273 18.22000  ?  95  SER A D    1 
ATOM   239  H HA   . SER A 1 14  ? 5.05542   -17.97220 -11.86729 1.000 19.72524  ?  95  SER A HA   1 
ATOM   240  H HB2  . SER A 1 14  ? 6.24943   -16.27400 -13.06289 1.000 21.11407  ?  95  SER A HB2  1 
ATOM   241  H HB3  . SER A 1 14  ? 4.85819   -15.95803 -14.13691 1.000 21.11407  ?  95  SER A HB3  1 
ATOM   242  N N    . PRO A 1 15  ? 2.61827   -17.63611 -11.26336 1.000 18.71532  ?  96  PRO A N    1 
ATOM   243  C CA   . PRO A 1 15  ? 1.19943   -17.34511 -10.96373 1.000 20.38641  ?  96  PRO A CA   1 
ATOM   244  C C    . PRO A 1 15  ? 0.89322   -15.84927 -10.92155 1.000 19.50730  ?  96  PRO A C    1 
ATOM   245  O O    . PRO A 1 15  ? -0.22067  -15.45028 -11.28661 1.000 22.80480  ?  96  PRO A O    1 
ATOM   246  C CB   . PRO A 1 15  ? 0.98204   -18.01937 -9.59673  1.000 26.98936  ?  96  PRO A CB   1 
ATOM   247  C CG   . PRO A 1 15  ? 2.21735   -18.87642 -9.37519  1.000 30.32229  ?  96  PRO A CG   1 
ATOM   248  C CD   . PRO A 1 15  ? 3.33126   -18.28523 -10.14106 1.000 19.82353  ?  96  PRO A CD   1 
ATOM   249  H HA   . PRO A 1 15  ? 0.55057   -17.82175 -11.69851 1.000 24.46369  ?  96  PRO A HA   1 
ATOM   250  H HB2  . PRO A 1 15  ? 0.89034   -17.26026 -8.81991  1.000 32.38723  ?  96  PRO A HB2  1 
ATOM   251  H HB3  . PRO A 1 15  ? 0.08205   -18.63360 -9.62583  1.000 32.38723  ?  96  PRO A HB3  1 
ATOM   252  H HG2  . PRO A 1 15  ? 2.45675   -18.88930 -8.31188  1.000 36.38675  ?  96  PRO A HG2  1 
ATOM   253  H HG3  . PRO A 1 15  ? 2.01631   -19.88923 -9.72435  1.000 36.38675  ?  96  PRO A HG3  1 
ATOM   254  H HD2  . PRO A 1 15  ? 3.87525   -17.55338 -9.54392  1.000 23.78824  ?  96  PRO A HD2  1 
ATOM   255  H HD3  . PRO A 1 15  ? 4.01431   -19.05479 -10.50066 1.000 23.78824  ?  96  PRO A HD3  1 
ATOM   256  N N    . TYR A 1 16  ? 1.86772   -15.01759 -10.55358 1.000 23.41475  ?  97  TYR A N    1 
ATOM   257  C CA   . TYR A 1 16  ? 1.61723   -13.57730 -10.47973 1.000 20.50542  ?  97  TYR A CA   1 
ATOM   258  C C    . TYR A 1 16  ? 1.40181   -12.99207 -11.86579 1.000 20.08512  ?  97  TYR A C    1 
ATOM   259  O O    . TYR A 1 16  ? 0.42825   -12.28690 -12.10815 1.000 21.59045  ?  97  TYR A O    1 
ATOM   260  C CB   . TYR A 1 16  ? 2.79354   -12.90896 -9.81779  1.000 21.82645  ?  97  TYR A CB   1 
ATOM   261  C CG   . TYR A 1 16  ? 2.60062   -11.44265 -9.62175  1.000 31.64809  ?  97  TYR A CG   1 
ATOM   262  C CD1  . TYR A 1 16  ? 1.81004   -10.96875 -8.60006  1.000 39.28499  ?  97  TYR A CD1  1 
ATOM   263  C CD2  . TYR A 1 16  ? 3.21446   -10.52466 -10.45536 1.000 37.04983  ?  97  TYR A CD2  1 
ATOM   264  C CE1  . TYR A 1 16  ? 1.63220   -9.62461  -8.41298  1.000 59.65775  ?  97  TYR A CE1  1 
ATOM   265  C CE2  . TYR A 1 16  ? 3.04876   -9.17650  -10.27628 1.000 43.13372  ?  97  TYR A CE2  1 
ATOM   266  C CZ   . TYR A 1 16  ? 2.25292   -8.73222  -9.25461  1.000 37.80616  ?  97  TYR A CZ   1 
ATOM   267  O OH   . TYR A 1 16  ? 2.07748   -7.38308  -9.06287  1.000 58.27524  ?  97  TYR A OH   1 
ATOM   268  H H    A TYR A 1 16  ? 2.81625   -15.29987 -10.30659 0.603 28.09770  ?  97  TYR A H    1 
ATOM   269  D D    B TYR A 1 16  ? 2.81682   -15.29761 -10.30619 0.397 28.09770  ?  97  TYR A D    1 
ATOM   270  H HA   . TYR A 1 16  ? 0.72032   -13.39612 -9.88742  1.000 24.60650  ?  97  TYR A HA   1 
ATOM   271  H HB2  . TYR A 1 16  ? 2.95123   -13.36069 -8.83841  1.000 26.19173  ?  97  TYR A HB2  1 
ATOM   272  H HB3  . TYR A 1 16  ? 3.67682   -13.05105 -10.44046 1.000 26.19173  ?  97  TYR A HB3  1 
ATOM   273  H HD1  . TYR A 1 16  ? 1.32281   -11.66752 -7.93619  1.000 47.14199  ?  97  TYR A HD1  1 
ATOM   274  H HD2  . TYR A 1 16  ? 3.83709   -10.87816 -11.26392 1.000 44.45980  ?  97  TYR A HD2  1 
ATOM   275  H HE1  . TYR A 1 16  ? 1.00729   -9.26678  -7.60809  1.000 71.58930  ?  97  TYR A HE1  1 
ATOM   276  H HE2  . TYR A 1 16  ? 3.53964   -8.47320  -10.93265 1.000 51.76046  ?  97  TYR A HE2  1 
ATOM   277  N N    . TYR A 1 17  ? 2.28538   -13.30878 -12.80889 1.000 17.82260  ?  98  TYR A N    1 
ATOM   278  C CA   . TYR A 1 17  ? 2.09485   -12.82004 -14.17557 1.000 15.10257  ?  98  TYR A CA   1 
ATOM   279  C C    . TYR A 1 17  ? 0.86136   -13.44063 -14.79648 1.000 17.73903  ?  98  TYR A C    1 
ATOM   280  O O    . TYR A 1 17  ? 0.13527   -12.77960 -15.53596 1.000 16.81797  ?  98  TYR A O    1 
ATOM   281  C CB   . TYR A 1 17  ? 3.34726   -13.10865 -15.00916 1.000 14.79825  ?  98  TYR A CB   1 
ATOM   282  C CG   . TYR A 1 17  ? 3.40695   -12.41999 -16.36497 1.000 13.63832  ?  98  TYR A CG   1 
ATOM   283  C CD1  . TYR A 1 17  ? 3.43904   -11.03631 -16.46346 1.000 13.67306  ?  98  TYR A CD1  1 
ATOM   284  C CD2  . TYR A 1 17  ? 3.45279   -13.16625 -17.51146 1.000 14.21000  ?  98  TYR A CD2  1 
ATOM   285  C CE1  . TYR A 1 17  ? 3.50908   -10.41023 -17.67277 1.000 14.54807  ?  98  TYR A CE1  1 
ATOM   286  C CE2  . TYR A 1 17  ? 3.54798   -12.53192 -18.76954 1.000 13.23652  ?  98  TYR A CE2  1 
ATOM   287  C CZ   . TYR A 1 17  ? 3.54335   -11.17201 -18.82213 1.000 13.87931  ?  98  TYR A CZ   1 
ATOM   288  O OH   . TYR A 1 17  ? 3.61093   -10.54525 -20.05942 1.000 16.11973  ?  98  TYR A OH   1 
ATOM   289  H H    A TYR A 1 17  ? 3.11686   -13.88239 -12.66740 0.560 21.38712  ?  98  TYR A H    1 
ATOM   290  D D    B TYR A 1 17  ? 3.11748   -13.88211 -12.66994 0.440 21.38712  ?  98  TYR A D    1 
ATOM   291  H HA   . TYR A 1 17  ? 1.95375   -11.73928 -14.16327 1.000 18.12309  ?  98  TYR A HA   1 
ATOM   292  H HB2  . TYR A 1 17  ? 4.21900   -12.78289 -14.44167 1.000 17.75790  ?  98  TYR A HB2  1 
ATOM   293  H HB3  . TYR A 1 17  ? 3.39927   -14.18251 -15.18867 1.000 17.75790  ?  98  TYR A HB3  1 
ATOM   294  H HD1  . TYR A 1 17  ? 3.40784   -10.44197 -15.56224 1.000 16.40768  ?  98  TYR A HD1  1 
ATOM   295  H HD2  . TYR A 1 17  ? 3.41603   -14.24408 -17.45373 1.000 17.05200  ?  98  TYR A HD2  1 
ATOM   296  H HE1  . TYR A 1 17  ? 3.53735   -9.33211  -17.72989 1.000 17.45769  ?  98  TYR A HE1  1 
ATOM   297  H HE2  . TYR A 1 17  ? 3.62318   -13.11616 -19.67475 1.000 15.88382  ?  98  TYR A HE2  1 
ATOM   298  N N    . ALA A 1 18  ? 0.56609   -14.70760 -14.47682 1.000 17.65824  ?  99  ALA A N    1 
ATOM   299  C CA   . ALA A 1 18  ? -0.64782  -15.31127 -15.02415 1.000 18.45368  ?  99  ALA A CA   1 
ATOM   300  C C    . ALA A 1 18  ? -1.88191  -14.52067 -14.56556 1.000 20.61377  ?  99  ALA A C    1 
ATOM   301  O O    . ALA A 1 18  ? -2.79967  -14.27506 -15.36007 1.000 21.81131  ?  99  ALA A O    1 
ATOM   302  C CB   . ALA A 1 18  ? -0.74255  -16.78452 -14.63330 1.000 18.39765  ?  99  ALA A CB   1 
ATOM   303  H H    A ALA A 1 18  ? 1.12182   -15.31101 -13.87063 0.751 21.18989  ?  99  ALA A H    1 
ATOM   304  D D    B ALA A 1 18  ? 1.12010   -15.31293 -13.87098 0.249 21.18989  ?  99  ALA A D    1 
ATOM   305  H HA   . ALA A 1 18  ? -0.60990  -15.28499 -16.11317 1.000 22.14442  ?  99  ALA A HA   1 
ATOM   306  H HB1  . ALA A 1 18  ? -1.61871  -17.22281 -15.11116 1.000 22.07718  ?  99  ALA A HB1  1 
ATOM   307  H HB2  . ALA A 1 18  ? 0.15889   -17.29876 -14.96658 1.000 22.07718  ?  99  ALA A HB2  1 
ATOM   308  H HB3  . ALA A 1 18  ? -0.83386  -16.85903 -13.54969 1.000 22.07718  ?  99  ALA A HB3  1 
ATOM   309  N N    . ASN A 1 19  ? -1.87695  -14.07026 -13.30940 1.000 21.34778  ?  100 ASN A N    1 
ATOM   310  C CA   . ASN A 1 19  ? -2.99376  -13.27831 -12.79011 1.000 23.21638  ?  100 ASN A CA   1 
ATOM   311  C C    . ASN A 1 19  ? -3.06592  -11.91206 -13.43416 1.000 26.29388  ?  100 ASN A C    1 
ATOM   312  O O    . ASN A 1 19  ? -4.16484  -11.42457 -13.72448 1.000 24.60093  ?  100 ASN A O    1 
ATOM   313  C CB   . ASN A 1 19  ? -2.86553  -13.11038 -11.27117 1.000 35.16684  ?  100 ASN A CB   1 
ATOM   314  C CG   . ASN A 1 19  ? -3.25058  -14.37989 -10.52237 1.000 51.93863  ?  100 ASN A CG   1 
ATOM   315  O OD1  . ASN A 1 19  ? -4.05995  -15.18402 -11.00282 1.000 44.04792  ?  100 ASN A OD1  1 
ATOM   316  N ND2  . ASN A 1 19  ? -2.66993  -14.56863 -9.34539  1.000 47.06035  ?  100 ASN A ND2  1 
ATOM   317  H H    A ASN A 1 19  ? -1.12812  -14.23286 -12.63619 0.652 25.61733  ?  100 ASN A H    1 
ATOM   318  D D    B ASN A 1 19  ? -1.12948  -14.23145 -12.63434 0.348 25.61733  ?  100 ASN A D    1 
ATOM   319  H HA   . ASN A 1 19  ? -3.91360  -13.81846 -13.01425 1.000 27.85966  ?  100 ASN A HA   1 
ATOM   320  H HB2  . ASN A 1 19  ? -1.83198  -12.86878 -11.02317 1.000 42.20021  ?  100 ASN A HB2  1 
ATOM   321  H HB3  . ASN A 1 19  ? -3.52529  -12.30748 -10.94228 1.000 42.20021  ?  100 ASN A HB3  1 
ATOM   322  N N    . GLU A 1 20  ? -1.92338  -11.25950 -13.63642 1.000 21.00147  ?  101 GLU A N    1 
ATOM   323  C CA   . GLU A 1 20  ? -1.93233  -9.97850  -14.34399 1.000 19.84545  ?  101 GLU A CA   1 
ATOM   324  C C    . GLU A 1 20  ? -2.49028  -10.14733 -15.74819 1.000 20.10576  ?  101 GLU A C    1 
ATOM   325  O O    . GLU A 1 20  ? -3.31209  -9.34653  -16.21993 1.000 20.47385  ?  101 GLU A O    1 
ATOM   326  C CB   . GLU A 1 20  ? -0.51618  -9.39502  -14.40987 1.000 18.05730  ?  101 GLU A CB   1 
ATOM   327  C CG   . GLU A 1 20  ? 0.05577   -9.09844  -13.07464 1.000 19.46306  ?  101 GLU A CG   1 
ATOM   328  C CD   . GLU A 1 20  ? 1.39651   -8.44801  -13.15999 1.000 21.09056  ?  101 GLU A CD   1 
ATOM   329  O OE1  . GLU A 1 20  ? 1.53242   -7.30582  -12.70652 1.000 23.32502  ?  101 GLU A OE1  1 
ATOM   330  O OE2  . GLU A 1 20  ? 2.32682   -9.08408  -13.70681 1.000 20.36155  -1 101 GLU A OE2  1 
ATOM   331  H H    A GLU A 1 20  ? -1.00302  -11.57838 -13.33367 0.750 25.20176  ?  101 GLU A H    1 
ATOM   332  D D    B GLU A 1 20  ? -1.00205  -11.57646 -13.33460 0.250 25.20176  ?  101 GLU A D    1 
ATOM   333  H HA   . GLU A 1 20  ? -2.56214  -9.28024  -13.79276 1.000 23.81454  ?  101 GLU A HA   1 
ATOM   334  H HB2  . GLU A 1 20  ? 0.13869   -10.11314 -14.90337 1.000 21.66876  ?  101 GLU A HB2  1 
ATOM   335  H HB3  . GLU A 1 20  ? -0.54395  -8.46467  -14.97711 1.000 21.66876  ?  101 GLU A HB3  1 
ATOM   336  H HG2  . GLU A 1 20  ? -0.61430  -8.42386  -12.54168 1.000 23.35567  ?  101 GLU A HG2  1 
ATOM   337  H HG3  . GLU A 1 20  ? 0.16623   -10.02984 -12.51930 1.000 23.35567  ?  101 GLU A HG3  1 
ATOM   338  N N    . VAL A 1 21  ? -2.05770  -11.18602 -16.44147 1.000 17.00125  ?  102 VAL A N    1 
ATOM   339  C CA   . VAL A 1 21  ? -2.47894  -11.37806 -17.82412 1.000 17.84683  ?  102 VAL A CA   1 
ATOM   340  C C    . VAL A 1 21  ? -3.95615  -11.71706 -17.87715 1.000 21.00838  ?  102 VAL A C    1 
ATOM   341  O O    . VAL A 1 21  ? -4.67122  -11.21040 -18.74127 1.000 22.14271  ?  102 VAL A O    1 
ATOM   342  C CB   . VAL A 1 21  ? -1.60129  -12.45832 -18.50911 1.000 15.90844  ?  102 VAL A CB   1 
ATOM   343  C CG1  . VAL A 1 21  ? -2.13845  -12.84482 -19.86599 1.000 21.09326  ?  102 VAL A CG1  1 
ATOM   344  C CG2  . VAL A 1 21  ? -0.20164  -11.94811 -18.64559 1.000 18.76098  ?  102 VAL A CG2  1 
ATOM   345  H H    A VAL A 1 21  ? -1.42564  -11.90333 -16.08598 0.954 20.40150  ?  102 VAL A H    1 
ATOM   346  D D    B VAL A 1 21  ? -1.42572  -11.90445 -16.08811 0.046 20.40150  ?  102 VAL A D    1 
ATOM   347  H HA   . VAL A 1 21  ? -2.33355  -10.44681 -18.37159 1.000 21.41619  ?  102 VAL A HA   1 
ATOM   348  H HB   . VAL A 1 21  ? -1.61287  -13.35383 -17.88780 1.000 19.09013  ?  102 VAL A HB   1 
ATOM   349  H HG11 . VAL A 1 21  ? -2.31879  -13.91966 -19.88326 1.000 25.31191  ?  102 VAL A HG11 1 
ATOM   350  H HG12 . VAL A 1 21  ? -3.07050  -12.30863 -20.04456 1.000 25.31191  ?  102 VAL A HG12 1 
ATOM   351  H HG13 . VAL A 1 21  ? -1.40488  -12.57873 -20.62702 1.000 25.31191  ?  102 VAL A HG13 1 
ATOM   352  H HG21 . VAL A 1 21  ? -0.20198  -11.08460 -19.31076 1.000 22.51317  ?  102 VAL A HG21 1 
ATOM   353  H HG22 . VAL A 1 21  ? 0.16831   -11.65933 -17.66180 1.000 22.51317  ?  102 VAL A HG22 1 
ATOM   354  H HG23 . VAL A 1 21  ? 0.42480   -12.73730 -19.06134 1.000 22.51317  ?  102 VAL A HG23 1 
ATOM   355  N N    . ALA A 1 22  ? -4.43438  -12.58693 -16.97067 1.000 23.05271  ?  103 ALA A N    1 
ATOM   356  C CA   . ALA A 1 22  ? -5.85402  -12.93370 -17.01532 1.000 29.49524  ?  103 ALA A CA   1 
ATOM   357  C C    . ALA A 1 22  ? -6.69833  -11.68122 -16.80933 1.000 26.00484  ?  103 ALA A C    1 
ATOM   358  O O    . ALA A 1 22  ? -7.66830  -11.44544 -17.54620 1.000 27.05465  ?  103 ALA A O    1 
ATOM   359  C CB   . ALA A 1 22  ? -6.17544  -14.00418 -15.96508 1.000 25.01851  ?  103 ALA A CB   1 
ATOM   360  H H    A ALA A 1 22  ? -3.89063  -13.04022 -16.23633 0.741 27.66325  ?  103 ALA A H    1 
ATOM   361  D D    B ALA A 1 22  ? -3.89275  -13.04145 -16.23552 0.259 27.66325  ?  103 ALA A D    1 
ATOM   362  H HA   . ALA A 1 22  ? -6.10019  -13.36251 -17.98672 1.000 35.39429  ?  103 ALA A HA   1 
ATOM   363  H HB1  . ALA A 1 22  ? -5.26763  -14.56363 -15.73925 1.000 30.02221  ?  103 ALA A HB1  1 
ATOM   364  H HB2  . ALA A 1 22  ? -6.54563  -13.51663 -15.06321 1.000 30.02221  ?  103 ALA A HB2  1 
ATOM   365  H HB3  . ALA A 1 22  ? -6.93617  -14.67533 -16.36376 1.000 30.02221  ?  103 ALA A HB3  1 
ATOM   366  N N    . ALA A 1 23  ? -6.31829  -10.85456 -15.82702 1.000 23.27749  ?  104 ALA A N    1 
ATOM   367  C CA   . ALA A 1 23  ? -7.04072  -9.60354  -15.58454 1.000 21.41343  ?  104 ALA A CA   1 
ATOM   368  C C    . ALA A 1 23  ? -6.94379  -8.68222  -16.79511 1.000 30.26880  ?  104 ALA A C    1 
ATOM   369  O O    . ALA A 1 23  ? -7.90052  -7.97344  -17.11633 1.000 27.80088  ?  104 ALA A O    1 
ATOM   370  C CB   . ALA A 1 23  ? -6.46096  -8.90383  -14.35604 1.000 22.61812  ?  104 ALA A CB   1 
ATOM   371  H H    A ALA A 1 23  ? -5.53307  -11.01904 -15.19711 0.766 27.93299  ?  104 ALA A H    1 
ATOM   372  D D    B ALA A 1 23  ? -5.53359  -11.01671 -15.19586 0.234 27.93299  ?  104 ALA A D    1 
ATOM   373  H HA   . ALA A 1 23  ? -8.09051  -9.82827  -15.39600 1.000 25.69612  ?  104 ALA A HA   1 
ATOM   374  H HB1  . ALA A 1 23  ? -6.93612  -7.92909  -14.24558 1.000 27.14174  ?  104 ALA A HB1  1 
ATOM   375  H HB2  . ALA A 1 23  ? -6.65628  -9.51458  -13.47460 1.000 27.14174  ?  104 ALA A HB2  1 
ATOM   376  H HB3  . ALA A 1 23  ? -5.38655  -8.78033  -14.49203 1.000 27.14174  ?  104 ALA A HB3  1 
ATOM   377  N N    . ALA A 1 24  ? -5.79431  -8.67081  -17.47709 1.000 21.50326  ?  105 ALA A N    1 
ATOM   378  C CA   . ALA A 1 24  ? -5.62763  -7.77147  -18.60197 1.000 19.64316  ?  105 ALA A CA   1 
ATOM   379  C C    . ALA A 1 24  ? -6.42669  -8.22762  -19.80853 1.000 25.00456  ?  105 ALA A C    1 
ATOM   380  O O    . ALA A 1 24  ? -6.96787  -7.41282  -20.55054 1.000 22.99596  ?  105 ALA A O    1 
ATOM   381  C CB   . ALA A 1 24  ? -4.14619  -7.68148  -18.97207 1.000 20.72569  ?  105 ALA A CB   1 
ATOM   382  H H    A ALA A 1 24  ? -4.98614  -9.25931  -17.27479 0.693 25.80391  ?  105 ALA A H    1 
ATOM   383  D D    B ALA A 1 24  ? -4.98484  -9.25821  -17.27681 0.307 25.80391  ?  105 ALA A D    1 
ATOM   384  H HA   . ALA A 1 24  ? -5.98474  -6.78399  -18.30965 1.000 23.57180  ?  105 ALA A HA   1 
ATOM   385  H HB1  . ALA A 1 24  ? -4.01045  -6.88268  -19.70118 1.000 24.87083  ?  105 ALA A HB1  1 
ATOM   386  H HB2  . ALA A 1 24  ? -3.56829  -7.46647  -18.07324 1.000 24.87083  ?  105 ALA A HB2  1 
ATOM   387  H HB3  . ALA A 1 24  ? -3.82875  -8.63265  -19.39939 1.000 24.87083  ?  105 ALA A HB3  1 
ATOM   388  N N    . ALA A 1 25  ? -6.50529  -9.52533  -20.03504 1.000 23.91392  ?  106 ALA A N    1 
ATOM   389  C CA   . ALA A 1 25  ? -7.20125  -10.00842 -21.21448 1.000 27.49232  ?  106 ALA A CA   1 
ATOM   390  C C    . ALA A 1 25  ? -8.69564  -9.71431  -21.11778 1.000 27.44706  ?  106 ALA A C    1 
ATOM   391  O O    . ALA A 1 25  ? -9.35496  -9.55272  -22.14340 1.000 26.67761  ?  106 ALA A O    1 
ATOM   392  C CB   . ALA A 1 25  ? -6.93060  -11.51342 -21.42596 1.000 26.53092  ?  106 ALA A CB   1 
ATOM   393  H H    A ALA A 1 25  ? -6.10914  -10.25200 -19.43886 0.683 28.69670  ?  106 ALA A H    1 
ATOM   394  D D    B ALA A 1 25  ? -6.11004  -10.25381 -19.44047 0.317 28.69670  ?  106 ALA A D    1 
ATOM   395  H HA   . ALA A 1 25  ? -6.81601  -9.49959  -22.09810 1.000 32.99078  ?  106 ALA A HA   1 
ATOM   396  H HB1  . ALA A 1 25  ? -7.64518  -12.08865 -20.83724 1.000 31.83711  ?  106 ALA A HB1  1 
ATOM   397  H HB2  . ALA A 1 25  ? -7.04530  -11.74938 -22.48392 1.000 31.83711  ?  106 ALA A HB2  1 
ATOM   398  H HB3  . ALA A 1 25  ? -5.91467  -11.74016 -21.10258 1.000 31.83711  ?  106 ALA A HB3  1 
ATOM   399  N N    . LYS A 1 26  ? -9.24026  -9.64278  -19.90057 1.000 25.67338  ?  107 LYS A N    1 
ATOM   400  C CA   . LYS A 1 26  ? -10.67122 -9.33551  -19.78687 1.000 39.74224  ?  107 LYS A CA   1 
ATOM   401  C C    . LYS A 1 26  ? -10.95845 -7.93058  -20.30961 1.000 39.70041  ?  107 LYS A C    1 
ATOM   402  O O    . LYS A 1 26  ? -12.00004 -7.68163  -20.92992 1.000 55.46911  ?  107 LYS A O    1 
ATOM   403  C CB   . LYS A 1 26  ? -11.15780 -9.50715  -18.34418 1.000 33.17830  ?  107 LYS A CB   1 
ATOM   404  C CG   . LYS A 1 26  ? -11.04427 -10.94268 -17.85043 1.000 49.01370  ?  107 LYS A CG   1 
ATOM   405  C CD   . LYS A 1 26  ? -11.39954 -11.07947 -16.36061 1.000 70.91046  ?  107 LYS A CD   1 
ATOM   406  C CE   . LYS A 1 26  ? -10.48216 -12.10358 -15.65645 1.000 74.42227  ?  107 LYS A CE   1 
ATOM   407  N NZ   . LYS A 1 26  ? -10.67657 -13.51416 -16.14549 1.000 90.01416  ?  107 LYS A NZ   1 
ATOM   408  H H    . LYS A 1 26  ? -8.74694  -9.78433  -19.01909 1.000 30.80806  ?  107 LYS A H    1 
ATOM   409  H HA   . LYS A 1 26  ? -11.23568 -10.04709 -20.38947 1.000 47.69069  ?  107 LYS A HA   1 
ATOM   410  H HB2  . LYS A 1 26  ? -10.55603 -8.87664  -17.68964 1.000 39.81396  ?  107 LYS A HB2  1 
ATOM   411  H HB3  . LYS A 1 26  ? -12.20551 -9.21218  -18.28590 1.000 39.81396  ?  107 LYS A HB3  1 
ATOM   412  H HG2  . LYS A 1 26  ? -11.72806 -11.57165 -18.42045 1.000 58.81644  ?  107 LYS A HG2  1 
ATOM   413  H HG3  . LYS A 1 26  ? -10.01924 -11.28736 -17.98685 1.000 58.81644  ?  107 LYS A HG3  1 
ATOM   414  H HD2  . LYS A 1 26  ? -11.27735 -10.11415 -15.86934 1.000 85.09255  ?  107 LYS A HD2  1 
ATOM   415  H HD3  . LYS A 1 26  ? -12.43084 -11.41893 -16.26421 1.000 85.09255  ?  107 LYS A HD3  1 
ATOM   416  H HE2  . LYS A 1 26  ? -9.44288  -11.82821 -15.83581 1.000 89.30672  ?  107 LYS A HE2  1 
ATOM   417  H HE3  . LYS A 1 26  ? -10.69247 -12.08893 -14.58703 1.000 89.30672  ?  107 LYS A HE3  1 
ATOM   418  N N    . GLN A 1 27  ? -10.03310 -6.99332  -20.07848 1.000 33.49911  ?  108 GLN A N    1 
ATOM   419  C CA   . GLN A 1 27  ? -10.22000 -5.58892  -20.45319 1.000 32.48144  ?  108 GLN A CA   1 
ATOM   420  C C    . GLN A 1 27  ? -9.99161  -5.31356  -21.93164 1.000 32.17510  ?  108 GLN A C    1 
ATOM   421  O O    . GLN A 1 27  ? -10.17343 -4.17079  -22.37204 1.000 40.95504  ?  108 GLN A O    1 
ATOM   422  C CB   . GLN A 1 27  ? -9.27941  -4.69108  -19.64421 1.000 29.46050  ?  108 GLN A CB   1 
ATOM   423  C CG   . GLN A 1 27  ? -9.57445  -4.70517  -18.15183 1.000 35.77567  ?  108 GLN A CG   1 
ATOM   424  C CD   . GLN A 1 27  ? -8.64498  -3.76887  -17.39536 1.000 82.10732  ?  108 GLN A CD   1 
ATOM   425  O OE1  . GLN A 1 27  ? -8.93832  -2.58266  -17.24225 1.000 94.05848  ?  108 GLN A OE1  1 
ATOM   426  N NE2  . GLN A 1 27  ? -7.51296  -4.29406  -16.92843 1.000 89.95712  ?  108 GLN A NE2  1 
ATOM   427  D D    . GLN A 1 27  ? -9.13616  -7.17831  -19.62939 0.000 40.19893  ?  108 GLN A D    1 
ATOM   428  H HA   . GLN A 1 27  ? -11.25017 -5.32495  -20.21409 1.000 38.97773  ?  108 GLN A HA   1 
ATOM   429  H HB2  . GLN A 1 27  ? -8.25470  -5.03415  -19.78690 1.000 35.35260  ?  108 GLN A HB2  1 
ATOM   430  H HB3  . GLN A 1 27  ? -9.38143  -3.66471  -19.99672 1.000 35.35260  ?  108 GLN A HB3  1 
ATOM   431  H HG2  . GLN A 1 27  ? -10.60123 -4.38043  -17.98339 1.000 42.93080  ?  108 GLN A HG2  1 
ATOM   432  H HG3  . GLN A 1 27  ? -9.43459  -5.71471  -17.76535 1.000 42.93080  ?  108 GLN A HG3  1 
ATOM   433  N N    . ILE A 1 28  ? -9.56848  -6.30914  -22.69700 1.000 29.13882  ?  109 ILE A N    1 
ATOM   434  C CA   . ILE A 1 28  ? -9.36688  -6.15265  -24.12542 1.000 29.59944  ?  109 ILE A CA   1 
ATOM   435  C C    . ILE A 1 28  ? -10.69661 -6.52046  -24.75530 1.000 38.54520  ?  109 ILE A C    1 
ATOM   436  O O    . ILE A 1 28  ? -11.22654 -7.61270  -24.52183 1.000 35.71068  ?  109 ILE A O    1 
ATOM   437  C CB   . ILE A 1 28  ? -8.22617  -7.05164  -24.62795 1.000 30.79861  ?  109 ILE A CB   1 
ATOM   438  C CG1  . ILE A 1 28  ? -6.91146  -6.51309  -24.06475 1.000 27.65409  ?  109 ILE A CG1  1 
ATOM   439  C CG2  . ILE A 1 28  ? -8.15807  -7.09406  -26.14645 1.000 25.78641  ?  109 ILE A CG2  1 
ATOM   440  C CD1  . ILE A 1 28  ? -5.75726  -7.46146  -24.18682 1.000 29.52295  ?  109 ILE A CD1  1 
ATOM   441  H H    A ILE A 1 28  ? -9.35524  -7.24472  -22.35113 0.920 34.96659  ?  109 ILE A H    1 
ATOM   442  D D    B ILE A 1 28  ? -9.35554  -7.24436  -22.34998 0.080 34.96659  ?  109 ILE A D    1 
ATOM   443  H HA   . ILE A 1 28  ? -9.09924  -5.12865  -24.38598 1.000 35.51933  ?  109 ILE A HA   1 
ATOM   444  H HB   . ILE A 1 28  ? -8.41083  -8.06993  -24.28577 1.000 36.95834  ?  109 ILE A HB   1 
ATOM   445  H HG12 . ILE A 1 28  ? -6.64909  -5.60194  -24.60239 1.000 33.18491  ?  109 ILE A HG12 1 
ATOM   446  H HG13 . ILE A 1 28  ? -7.04931  -6.29454  -23.00582 1.000 33.18491  ?  109 ILE A HG13 1 
ATOM   447  H HG21 . ILE A 1 28  ? -9.15646  -6.92826  -26.55122 1.000 30.94369  ?  109 ILE A HG21 1 
ATOM   448  H HG22 . ILE A 1 28  ? -7.48188  -6.31269  -26.49332 1.000 30.94369  ?  109 ILE A HG22 1 
ATOM   449  H HG23 . ILE A 1 28  ? -7.78821  -8.07093  -26.45794 1.000 30.94369  ?  109 ILE A HG23 1 
ATOM   450  H HD11 . ILE A 1 28  ? -6.14145  -8.47179  -24.32729 1.000 35.42753  ?  109 ILE A HD11 1 
ATOM   451  H HD12 . ILE A 1 28  ? -5.14955  -7.17233  -25.04426 1.000 35.42753  ?  109 ILE A HD12 1 
ATOM   452  H HD13 . ILE A 1 28  ? -5.16097  -7.41388  -23.27563 1.000 35.42753  ?  109 ILE A HD13 1 
ATOM   453  N N    . THR A 1 29  ? -11.25032 -5.59833  -25.52440 1.000 49.98042  ?  110 THR A N    1 
ATOM   454  C CA   . THR A 1 29  ? -12.63140 -5.72917  -25.96371 1.000 50.17146  ?  110 THR A CA   1 
ATOM   455  C C    . THR A 1 29  ? -12.75440 -6.52903  -27.23943 1.000 42.62849  ?  110 THR A C    1 
ATOM   456  O O    . THR A 1 29  ? -13.79477 -7.15369  -27.46958 1.000 53.67078  ?  110 THR A O    1 
ATOM   457  C CB   . THR A 1 29  ? -13.25068 -4.33736  -26.14403 1.000 36.27168  ?  110 THR A CB   1 
ATOM   458  O OG1  . THR A 1 29  ? -12.45167 -3.57552  -27.05645 1.000 45.66287  ?  110 THR A OG1  1 
ATOM   459  C CG2  . THR A 1 29  ? -13.32646 -3.62864  -24.78231 1.000 37.56669  ?  110 THR A CG2  1 
ATOM   460  H H    A THR A 1 29  ? -10.77668 -4.75858  -25.85738 0.491 59.97650  ?  110 THR A H    1 
ATOM   461  D D    B THR A 1 29  ? -10.77696 -4.75848  -25.85754 0.509 59.97650  ?  110 THR A D    1 
ATOM   462  H HA   . THR A 1 29  ? -13.21100 -6.24653  -25.19918 1.000 60.20575  ?  110 THR A HA   1 
ATOM   463  H HB   . THR A 1 29  ? -14.26018 -4.41625  -26.54750 1.000 43.52602  ?  110 THR A HB   1 
ATOM   464  H HG21 . THR A 1 29  ? -13.20345 -2.55366  -24.91417 1.000 45.08003  ?  110 THR A HG21 1 
ATOM   465  H HG22 . THR A 1 29  ? -14.29299 -3.81951  -24.31596 1.000 45.08003  ?  110 THR A HG22 1 
ATOM   466  H HG23 . THR A 1 29  ? -12.53808 -3.99702  -24.12592 1.000 45.08003  ?  110 THR A HG23 1 
ATOM   467  N N    . ASP A 1 30  ? -11.73099 -6.54160  -28.06769 1.000 40.45754  ?  111 ASP A N    1 
ATOM   468  C CA   . ASP A 1 30  ? -11.78187 -7.35679  -29.27205 1.000 30.07009  ?  111 ASP A CA   1 
ATOM   469  C C    . ASP A 1 30  ? -11.64953 -8.80459  -28.84047 1.000 48.54917  ?  111 ASP A C    1 
ATOM   470  O O    . ASP A 1 30  ? -10.61060 -9.17729  -28.27577 1.000 36.41512  ?  111 ASP A O    1 
ATOM   471  C CB   . ASP A 1 30  ? -10.64883 -6.96495  -30.19573 1.000 35.12371  ?  111 ASP A CB   1 
ATOM   472  C CG   . ASP A 1 30  ? -10.56773 -7.84212  -31.42357 1.000 45.76085  ?  111 ASP A CG   1 
ATOM   473  O OD1  . ASP A 1 30  ? -11.21186 -8.91222  -31.45696 1.000 51.99622  ?  111 ASP A OD1  1 
ATOM   474  O OD2  . ASP A 1 30  ? -9.85864  -7.44733  -32.37126 1.000 62.78512  -1 111 ASP A OD2  1 
ATOM   475  H H    A ASP A 1 30  ? -10.86838 -6.01215  -27.94130 0.502 48.54904  ?  111 ASP A H    1 
ATOM   476  D D    B ASP A 1 30  ? -10.86803 -6.01252  -27.94213 0.498 48.54904  ?  111 ASP A D    1 
ATOM   477  H HA   . ASP A 1 30  ? -12.71549 -7.21609  -29.81671 1.000 36.08411  ?  111 ASP A HA   1 
ATOM   478  H HB2  . ASP A 1 30  ? -10.79806 -5.93665  -30.52502 1.000 42.14845  ?  111 ASP A HB2  1 
ATOM   479  H HB3  . ASP A 1 30  ? -9.70516  -7.05065  -29.65699 1.000 42.14845  ?  111 ASP A HB3  1 
ATOM   480  N N    . PRO A 1 31  ? -12.64739 -9.65710  -29.09136 1.000 49.39674  ?  112 PRO A N    1 
ATOM   481  C CA   . PRO A 1 31  ? -12.57190 -11.03252 -28.56347 1.000 58.67245  ?  112 PRO A CA   1 
ATOM   482  C C    . PRO A 1 31  ? -11.40209 -11.84162 -29.11014 1.000 44.83043  ?  112 PRO A C    1 
ATOM   483  O O    . PRO A 1 31  ? -10.91505 -12.74086 -28.40759 1.000 44.22383  ?  112 PRO A O    1 
ATOM   484  C CB   . PRO A 1 31  ? -13.92219 -11.65868 -28.95583 1.000 56.91804  ?  112 PRO A CB   1 
ATOM   485  C CG   . PRO A 1 31  ? -14.80327 -10.51112 -29.31603 1.000 65.73649  ?  112 PRO A CG   1 
ATOM   486  C CD   . PRO A 1 31  ? -13.89630 -9.42004  -29.83436 1.000 62.93714  ?  112 PRO A CD   1 
ATOM   487  H HA   . PRO A 1 31  ? -12.50357 -10.98980 -27.47645 1.000 70.40694  ?  112 PRO A HA   1 
ATOM   488  H HB2  . PRO A 1 31  ? -13.78596 -12.32555 -29.80720 1.000 68.30165  ?  112 PRO A HB2  1 
ATOM   489  H HB3  . PRO A 1 31  ? -14.33160 -12.21198 -28.11064 1.000 68.30165  ?  112 PRO A HB3  1 
ATOM   490  H HG2  . PRO A 1 31  ? -15.50914 -10.82115 -30.08657 1.000 78.88379  ?  112 PRO A HG2  1 
ATOM   491  H HG3  . PRO A 1 31  ? -15.34223 -10.17332 -28.43086 1.000 78.88379  ?  112 PRO A HG3  1 
ATOM   492  H HD2  . PRO A 1 31  ? -13.73727 -9.52165  -30.90790 1.000 75.52457  ?  112 PRO A HD2  1 
ATOM   493  H HD3  . PRO A 1 31  ? -14.30334 -8.43423  -29.60944 1.000 75.52457  ?  112 PRO A HD3  1 
ATOM   494  N N    . THR A 1 32  ? -10.93979 -11.57524 -30.34133 1.000 41.93749  ?  113 THR A N    1 
ATOM   495  C CA   . THR A 1 32  ? -9.81146  -12.33907 -30.85981 1.000 39.83152  ?  113 THR A CA   1 
ATOM   496  C C    . THR A 1 32  ? -8.49260  -11.89161 -30.22549 1.000 44.60496  ?  113 THR A C    1 
ATOM   497  O O    . THR A 1 32  ? -7.66835  -12.73189 -29.83997 1.000 36.52206  ?  113 THR A O    1 
ATOM   498  C CB   . THR A 1 32  ? -9.74867  -12.28793 -32.39316 1.000 49.54827  ?  113 THR A CB   1 
ATOM   499  O OG1  . THR A 1 32  ? -8.38433  -12.47189 -32.81104 1.000 59.90944  ?  113 THR A OG1  1 
ATOM   500  C CG2  . THR A 1 32  ? -10.24546 -10.98266 -32.98710 1.000 50.76099  ?  113 THR A CG2  1 
ATOM   501  H H    A THR A 1 32  ? -11.31357 -10.86595 -30.97188 0.427 50.32499  ?  113 THR A H    1 
ATOM   502  D D    B THR A 1 32  ? -11.31217 -10.86646 -30.97329 0.573 50.32499  ?  113 THR A D    1 
ATOM   503  H HA   . THR A 1 32  ? -9.96473  -13.38716 -30.60269 1.000 47.79782  ?  113 THR A HA   1 
ATOM   504  H HB   . THR A 1 32  ? -10.40318 -13.07488 -32.76790 1.000 59.45793  ?  113 THR A HB   1 
ATOM   505  H HG21 . THR A 1 32  ? -9.74696  -10.14081 -32.50658 1.000 60.91319  ?  113 THR A HG21 1 
ATOM   506  H HG22 . THR A 1 32  ? -10.03453 -10.95536 -34.05615 1.000 60.91319  ?  113 THR A HG22 1 
ATOM   507  H HG23 . THR A 1 32  ? -11.32098 -10.88990 -32.83626 1.000 60.91319  ?  113 THR A HG23 1 
ATOM   508  N N    . LEU A 1 33  ? -8.28668  -10.58326 -30.07770 1.000 34.81509  ?  114 LEU A N    1 
ATOM   509  C CA   . LEU A 1 33  ? -7.10004  -10.10594 -29.37038 1.000 34.07634  ?  114 LEU A CA   1 
ATOM   510  C C    . LEU A 1 33  ? -7.12740  -10.53454 -27.90914 1.000 28.46951  ?  114 LEU A C    1 
ATOM   511  O O    . LEU A 1 33  ? -6.07286  -10.81676 -27.31883 1.000 25.88978  ?  114 LEU A O    1 
ATOM   512  C CB   . LEU A 1 33  ? -7.02600  -8.58668  -29.48388 1.000 34.04825  ?  114 LEU A CB   1 
ATOM   513  C CG   . LEU A 1 33  ? -5.66489  -7.90362  -29.58267 1.000 50.11388  ?  114 LEU A CG   1 
ATOM   514  C CD1  . LEU A 1 33  ? -4.92245  -8.34817  -30.82652 1.000 34.20170  ?  114 LEU A CD1  1 
ATOM   515  C CD2  . LEU A 1 33  ? -5.85201  -6.38018  -29.54159 1.000 41.32473  ?  114 LEU A CD2  1 
ATOM   516  H H    A LEU A 1 33  ? -8.90356  -9.84907  -30.42532 0.687 41.77810  ?  114 LEU A H    1 
ATOM   517  D D    B LEU A 1 33  ? -8.90192  -9.84723  -30.42432 0.313 41.77810  ?  114 LEU A D    1 
ATOM   518  H HA   . LEU A 1 33  ? -6.20323  -10.52573 -29.82601 1.000 40.89161  ?  114 LEU A HA   1 
ATOM   519  H HB2  . LEU A 1 33  ? -7.57613  -8.30179  -30.38071 1.000 40.85790  ?  114 LEU A HB2  1 
ATOM   520  H HB3  . LEU A 1 33  ? -7.51212  -8.17194  -28.60084 1.000 40.85790  ?  114 LEU A HB3  1 
ATOM   521  H HG   . LEU A 1 33  ? -5.04426  -8.19091  -28.73391 1.000 60.13665  ?  114 LEU A HG   1 
ATOM   522  H HD11 . LEU A 1 33  ? -4.52013  -7.47047  -31.33237 1.000 41.04204  ?  114 LEU A HD11 1 
ATOM   523  H HD12 . LEU A 1 33  ? -4.11031  -9.01456  -30.53591 1.000 41.04204  ?  114 LEU A HD12 1 
ATOM   524  H HD13 . LEU A 1 33  ? -5.61528  -8.87182  -31.48522 1.000 41.04204  ?  114 LEU A HD13 1 
ATOM   525  H HD21 . LEU A 1 33  ? -6.83637  -6.15448  -29.13147 1.000 49.58968  ?  114 LEU A HD21 1 
ATOM   526  H HD22 . LEU A 1 33  ? -5.07754  -5.94440  -28.91041 1.000 49.58968  ?  114 LEU A HD22 1 
ATOM   527  H HD23 . LEU A 1 33  ? -5.77188  -5.98536  -30.55440 1.000 49.58968  ?  114 LEU A HD23 1 
ATOM   528  N N    . SER A 1 34  ? -8.30984  -10.59838 -27.30045 1.000 26.38005  ?  115 SER A N    1 
ATOM   529  C CA   . SER A 1 34  ? -8.39844  -11.04261 -25.91428 1.000 24.96742  ?  115 SER A CA   1 
ATOM   530  C C    . SER A 1 34  ? -7.91096  -12.48712 -25.77522 1.000 28.35627  ?  115 SER A C    1 
ATOM   531  O O    . SER A 1 34  ? -7.24229  -12.83651 -24.78813 1.000 23.71355  ?  115 SER A O    1 
ATOM   532  C CB   . SER A 1 34  ? -9.85052  -10.89884 -25.42105 1.000 28.64400  ?  115 SER A CB   1 
ATOM   533  O OG   . SER A 1 34  ? -9.96394  -11.18982 -24.04151 1.000 29.63826  ?  115 SER A OG   1 
ATOM   534  H H    A SER A 1 34  ? -9.20298  -10.35540 -27.72900 0.930 31.65606  ?  115 SER A H    1 
ATOM   535  D D    B SER A 1 34  ? -9.20424  -10.35601 -27.72672 0.070 31.65606  ?  115 SER A D    1 
ATOM   536  H HA   . SER A 1 34  ? -7.76618  -10.41501 -25.28622 1.000 29.96091  ?  115 SER A HA   1 
ATOM   537  H HB2  . SER A 1 34  ? -10.17973 -9.87392  -25.59207 1.000 34.37279  ?  115 SER A HB2  1 
ATOM   538  H HB3  . SER A 1 34  ? -10.48117 -11.59098 -25.97902 1.000 34.37279  ?  115 SER A HB3  1 
ATOM   539  N N    . SER A 1 35  ? -8.20909  -13.33417 -26.77034 1.000 26.21106  ?  116 SER A N    1 
ATOM   540  C CA   . SER A 1 35  ? -7.78526  -14.72953 -26.68986 1.000 37.46731  ?  116 SER A CA   1 
ATOM   541  C C    . SER A 1 35  ? -6.27654  -14.83166 -26.80809 1.000 28.38758  ?  116 SER A C    1 
ATOM   542  O O    . SER A 1 35  ? -5.63395  -15.62313 -26.10054 1.000 24.81259  ?  116 SER A O    1 
ATOM   543  C CB   . SER A 1 35  ? -8.43504  -15.56432 -27.78438 1.000 32.32495  ?  116 SER A CB   1 
ATOM   544  O OG   . SER A 1 35  ? -9.72930  -15.99475 -27.37047 1.000 79.87142  ?  116 SER A OG   1 
ATOM   545  H H    A SER A 1 35  ? -8.72542  -13.08941 -27.61526 0.679 31.45327  ?  116 SER A H    1 
ATOM   546  D D    B SER A 1 35  ? -8.72520  -13.09189 -27.61611 0.321 31.45327  ?  116 SER A D    1 
ATOM   547  H HA   . SER A 1 35  ? -8.10854  -15.12901 -25.72860 1.000 44.96077  ?  116 SER A HA   1 
ATOM   548  H HB2  . SER A 1 35  ? -8.53030  -14.96004 -28.68652 1.000 38.78994  ?  116 SER A HB2  1 
ATOM   549  H HB3  . SER A 1 35  ? -7.81437  -16.43772 -27.98452 1.000 38.78994  ?  116 SER A HB3  1 
ATOM   550  N N    . LYS A 1 36  ? -5.70187  -14.05605 -27.72191 1.000 22.66056  ?  117 LYS A N    1 
ATOM   551  C CA   . LYS A 1 36  ? -4.25159  -14.03454 -27.88590 1.000 27.60951  ?  117 LYS A CA   1 
ATOM   552  C C    . LYS A 1 36  ? -3.58467  -13.49602 -26.63302 1.000 21.47796  ?  117 LYS A C    1 
ATOM   553  O O    . LYS A 1 36  ? -2.58389  -14.05819 -26.16296 1.000 19.84955  ?  117 LYS A O    1 
ATOM   554  C CB   . LYS A 1 36  ? -3.91519  -13.22857 -29.12945 1.000 24.70513  ?  117 LYS A CB   1 
ATOM   555  C CG   . LYS A 1 36  ? -4.15222  -14.02778 -30.40737 1.000 30.84447  ?  117 LYS A CG   1 
ATOM   556  C CD   . LYS A 1 36  ? -4.31493  -13.15703 -31.64794 1.000 55.98114  ?  117 LYS A CD   1 
ATOM   557  C CE   . LYS A 1 36  ? -2.98849  -12.54352 -32.11001 1.000 77.35672  ?  117 LYS A CE   1 
ATOM   558  N NZ   . LYS A 1 36  ? -2.80626  -12.59269 -33.60484 1.000 58.10314  ?  117 LYS A NZ   1 
ATOM   559  H H    A LYS A 1 36  ? -6.20480  -13.43730 -28.35800 0.703 27.19267  ?  117 LYS A H    1 
ATOM   560  D D    B LYS A 1 36  ? -6.20245  -13.43652 -28.35910 0.297 27.19267  ?  117 LYS A D    1 
ATOM   561  H HA   . LYS A 1 36  ? -3.85732  -15.03921 -28.03852 1.000 33.13141  ?  117 LYS A HA   1 
ATOM   562  H HB2  . LYS A 1 36  ? -4.54452  -12.33917 -29.16115 1.000 29.64615  ?  117 LYS A HB2  1 
ATOM   563  H HB3  . LYS A 1 36  ? -2.86439  -12.94076 -29.09656 1.000 29.64615  ?  117 LYS A HB3  1 
ATOM   564  H HG2  . LYS A 1 36  ? -3.30080  -14.68784 -30.57322 1.000 37.01337  ?  117 LYS A HG2  1 
ATOM   565  H HG3  . LYS A 1 36  ? -5.06272  -14.61572 -30.29152 1.000 37.01337  ?  117 LYS A HG3  1 
ATOM   566  H HD2  . LYS A 1 36  ? -4.70782  -13.76570 -32.46235 1.000 67.17737  ?  117 LYS A HD2  1 
ATOM   567  H HD3  . LYS A 1 36  ? -5.00448  -12.34289 -31.42479 1.000 67.17737  ?  117 LYS A HD3  1 
ATOM   568  H HE2  . LYS A 1 36  ? -2.95503  -11.49848 -31.80199 1.000 92.82807  ?  117 LYS A HE2  1 
ATOM   569  H HE3  . LYS A 1 36  ? -2.16556  -13.09332 -31.65329 1.000 92.82807  ?  117 LYS A HE3  1 
ATOM   570  N N    . ALA A 1 37  ? -4.13971  -12.44041 -26.04587 1.000 19.43046  ?  118 ALA A N    1 
ATOM   571  C CA   . ALA A 1 37  ? -3.59412  -11.92359 -24.80339 1.000 16.86467  ?  118 ALA A CA   1 
ATOM   572  C C    . ALA A 1 37  ? -3.63496  -12.95602 -23.69144 1.000 23.00135  ?  118 ALA A C    1 
ATOM   573  O O    . ALA A 1 37  ? -2.67895  -13.09999 -22.91374 1.000 18.26698  ?  118 ALA A O    1 
ATOM   574  C CB   . ALA A 1 37  ? -4.38981  -10.68312 -24.37728 1.000 21.09311  ?  118 ALA A CB   1 
ATOM   575  H H    A ALA A 1 37  ? -4.95077  -11.93295 -26.39953 0.738 23.31655  ?  118 ALA A H    1 
ATOM   576  D D    B ALA A 1 37  ? -4.95064  -11.93129 -26.39744 0.262 23.31655  ?  118 ALA A D    1 
ATOM   577  H HA   . ALA A 1 37  ? -2.55247  -11.65063 -24.97239 1.000 20.23760  ?  118 ALA A HA   1 
ATOM   578  H HB1  . ALA A 1 37  ? -5.24985  -10.99879 -23.78670 1.000 25.31174  ?  118 ALA A HB1  1 
ATOM   579  H HB2  . ALA A 1 37  ? -3.74638  -10.03647 -23.78067 1.000 25.31174  ?  118 ALA A HB2  1 
ATOM   580  H HB3  . ALA A 1 37  ? -4.72537  -10.15327 -25.26877 1.000 25.31174  ?  118 ALA A HB3  1 
ATOM   581  N N    . ALA A 1 38  ? -4.73800  -13.69046 -23.57293 1.000 21.36853  ?  119 ALA A N    1 
ATOM   582  C CA   . ALA A 1 38  ? -4.83354  -14.66810 -22.49855 1.000 21.45161  ?  119 ALA A CA   1 
ATOM   583  C C    . ALA A 1 38  ? -3.75383  -15.73905 -22.63156 1.000 18.25526  ?  119 ALA A C    1 
ATOM   584  O O    . ALA A 1 38  ? -3.28776  -16.25785 -21.62060 1.000 22.03654  ?  119 ALA A O    1 
ATOM   585  C CB   . ALA A 1 38  ? -6.22343  -15.34686 -22.50686 1.000 21.47700  ?  119 ALA A CB   1 
ATOM   586  H H    A ALA A 1 38  ? -5.55329  -13.63382 -24.18325 0.654 25.64223  ?  119 ALA A H    1 
ATOM   587  D D    B ALA A 1 38  ? -5.55447  -13.63570 -24.18185 0.346 25.64223  ?  119 ALA A D    1 
ATOM   588  H HA   . ALA A 1 38  ? -4.70943  -14.14789 -21.54877 1.000 25.74194  ?  119 ALA A HA   1 
ATOM   589  H HB1  . ALA A 1 38  ? -6.18690  -16.22244 -23.15503 1.000 25.77240  ?  119 ALA A HB1  1 
ATOM   590  H HB2  . ALA A 1 38  ? -6.47775  -15.64722 -21.49039 1.000 25.77240  ?  119 ALA A HB2  1 
ATOM   591  H HB3  . ALA A 1 38  ? -6.96226  -14.63809 -22.88087 1.000 25.77240  ?  119 ALA A HB3  1 
ATOM   592  N N    . SER A 1 39  ? -3.38322  -16.10346 -23.84757 1.000 18.65889  ?  120 SER A N    1 
ATOM   593  C CA   . SER A 1 39  ? -2.42373  -17.17869 -24.05380 1.000 16.60477  ?  120 SER A CA   1 
ATOM   594  C C    . SER A 1 39  ? -1.03777  -16.79706 -23.53969 1.000 17.22194  ?  120 SER A C    1 
ATOM   595  O O    . SER A 1 39  ? -0.19902  -17.69088 -23.34577 1.000 18.72366  ?  120 SER A O    1 
ATOM   596  C CB   . SER A 1 39  ? -2.35065  -17.54783 -25.52754 1.000 18.91464  ?  120 SER A CB   1 
ATOM   597  O OG   . SER A 1 39  ? -1.60619  -16.60167 -26.25053 1.000 19.49072  ?  120 SER A OG   1 
ATOM   598  H H    A SER A 1 39  ? -3.72550  -15.67799 -24.70909 0.480 22.39067  ?  120 SER A H    1 
ATOM   599  D D    B SER A 1 39  ? -3.72443  -15.67915 -24.71009 0.520 22.39067  ?  120 SER A D    1 
ATOM   600  H HA   . SER A 1 39  ? -2.75946  -18.06411 -23.51396 1.000 19.92572  ?  120 SER A HA   1 
ATOM   601  H HB2  . SER A 1 39  ? -1.87263  -18.52261 -25.62447 1.000 22.69757  ?  120 SER A HB2  1 
ATOM   602  H HB3  . SER A 1 39  ? -3.36178  -17.58651 -25.93279 1.000 22.69757  ?  120 SER A HB3  1 
ATOM   603  N N    . VAL A 1 40  ? -0.78373  -15.50887 -23.29931 1.000 16.35609  ?  121 VAL A N    1 
ATOM   604  C CA   . VAL A 1 40  ? 0.52111   -15.06279 -22.79258 1.000 15.88937  ?  121 VAL A CA   1 
ATOM   605  C C    . VAL A 1 40  ? 0.80076   -15.63066 -21.42208 1.000 16.70408  ?  121 VAL A C    1 
ATOM   606  O O    . VAL A 1 40  ? 1.95997   -15.80745 -21.03229 1.000 16.89120  ?  121 VAL A O    1 
ATOM   607  C CB   . VAL A 1 40  ? 0.60744   -13.52518 -22.81972 1.000 15.88470  ?  121 VAL A CB   1 
ATOM   608  C CG1  . VAL A 1 40  ? 1.86965   -12.99743 -22.12818 1.000 18.00733  ?  121 VAL A CG1  1 
ATOM   609  C CG2  . VAL A 1 40  ? 0.52350   -13.03773 -24.26296 1.000 18.56310  ?  121 VAL A CG2  1 
ATOM   610  H H    A VAL A 1 40  ? -1.45243  -14.75212 -23.44275 0.846 19.62731  ?  121 VAL A H    1 
ATOM   611  D D    B VAL A 1 40  ? -1.45082  -14.75056 -23.44201 0.154 19.62731  ?  121 VAL A D    1 
ATOM   612  H HA   . VAL A 1 40  ? 1.29622   -15.44572 -23.45641 1.000 19.06725  ?  121 VAL A HA   1 
ATOM   613  H HB   . VAL A 1 40  ? -0.23377  -13.12189 -22.25595 1.000 19.06164  ?  121 VAL A HB   1 
ATOM   614  H HG11 . VAL A 1 40  ? 1.67980   -12.91485 -21.05802 1.000 21.60880  ?  121 VAL A HG11 1 
ATOM   615  H HG12 . VAL A 1 40  ? 2.68968   -13.69274 -22.30763 1.000 21.60880  ?  121 VAL A HG12 1 
ATOM   616  H HG13 . VAL A 1 40  ? 2.11607   -12.01819 -22.53862 1.000 21.60880  ?  121 VAL A HG13 1 
ATOM   617  H HG21 . VAL A 1 40  ? 0.22863   -11.98837 -24.26653 1.000 22.27572  ?  121 VAL A HG21 1 
ATOM   618  H HG22 . VAL A 1 40  ? 1.50034   -13.15093 -24.73314 1.000 22.27572  ?  121 VAL A HG22 1 
ATOM   619  H HG23 . VAL A 1 40  ? -0.21705  -13.63373 -24.79633 1.000 22.27572  ?  121 VAL A HG23 1 
ATOM   620  N N    . ALA A 1 41  ? -0.24210  -15.95438 -20.65626 1.000 16.01696  ?  122 ALA A N    1 
ATOM   621  C CA   . ALA A 1 41  ? -0.01873  -16.52373 -19.32703 1.000 16.41261  ?  122 ALA A CA   1 
ATOM   622  C C    . ALA A 1 41  ? 0.62305   -17.89867 -19.37454 1.000 14.60118  ?  122 ALA A C    1 
ATOM   623  O O    . ALA A 1 41  ? 1.07247   -18.39415 -18.33374 1.000 17.54792  ?  122 ALA A O    1 
ATOM   624  C CB   . ALA A 1 41  ? -1.37692  -16.61322 -18.59037 1.000 19.73622  ?  122 ALA A CB   1 
ATOM   625  H H    A ALA A 1 41  ? -1.22099  -15.83863 -20.91850 0.612 19.22035  ?  122 ALA A H    1 
ATOM   626  D D    B ALA A 1 41  ? -1.22126  -15.83898 -20.91766 0.388 19.22035  ?  122 ALA A D    1 
ATOM   627  H HA   . ALA A 1 41  ? 0.64893   -15.87159 -18.76397 1.000 19.69514  ?  122 ALA A HA   1 
ATOM   628  H HB1  . ALA A 1 41  ? -1.81597  -15.61719 -18.53329 1.000 23.68346  ?  122 ALA A HB1  1 
ATOM   629  H HB2  . ALA A 1 41  ? -2.03795  -17.27961 -19.14451 1.000 23.68346  ?  122 ALA A HB2  1 
ATOM   630  H HB3  . ALA A 1 41  ? -1.21109  -17.00442 -17.58660 1.000 23.68346  ?  122 ALA A HB3  1 
ATOM   631  N N    . ASN A 1 42  ? 0.66209   -18.54245 -20.53578 1.000 13.78409  ?  123 ASN A N    1 
ATOM   632  C CA   . ASN A 1 42  ? 1.31107   -19.83594 -20.68284 1.000 14.54035  ?  123 ASN A CA   1 
ATOM   633  C C    . ASN A 1 42  ? 2.74173   -19.72960 -21.19342 1.000 16.49300  ?  123 ASN A C    1 
ATOM   634  O O    . ASN A 1 42  ? 3.35377   -20.75759 -21.51755 1.000 16.56791  ?  123 ASN A O    1 
ATOM   635  C CB   . ASN A 1 42  ? 0.51795   -20.72772 -21.65860 1.000 16.79837  ?  123 ASN A CB   1 
ATOM   636  C CG   . ASN A 1 42  ? -0.86188  -21.02664 -21.16666 1.000 28.62124  ?  123 ASN A CG   1 
ATOM   637  O OD1  . ASN A 1 42  ? -1.08989  -21.19092 -19.96569 1.000 31.79448  ?  123 ASN A OD1  1 
ATOM   638  N ND2  . ASN A 1 42  ? -1.80476  -21.09310 -22.10571 1.000 31.75907  ?  123 ASN A ND2  1 
ATOM   639  H H    A ASN A 1 42  ? 0.24886   -18.18853 -21.39856 0.548 16.54090  ?  123 ASN A H    1 
ATOM   640  D D    B ASN A 1 42  ? 0.24832   -18.18710 -21.39771 0.452 16.54090  ?  123 ASN A D    1 
ATOM   641  H HA   . ASN A 1 42  ? 1.32349   -20.30628 -19.69962 1.000 17.44842  ?  123 ASN A HA   1 
ATOM   642  H HB2  . ASN A 1 42  ? 0.43205   -20.21767 -22.61806 1.000 20.15805  ?  123 ASN A HB2  1 
ATOM   643  H HB3  . ASN A 1 42  ? 1.04445   -21.67371 -21.78511 1.000 20.15805  ?  123 ASN A HB3  1 
ATOM   644  N N    . ILE A 1 43  ? 3.28053   -18.52414 -21.30313 1.000 14.25544  ?  124 ILE A N    1 
ATOM   645  C CA   . ILE A 1 43  ? 4.66028   -18.29816 -21.76637 1.000 14.10641  ?  124 ILE A CA   1 
ATOM   646  C C    . ILE A 1 43  ? 5.53161   -18.03707 -20.53947 1.000 13.39112  ?  124 ILE A C    1 
ATOM   647  O O    . ILE A 1 43  ? 5.20860   -17.13163 -19.76950 1.000 13.99399  ?  124 ILE A O    1 
ATOM   648  C CB   . ILE A 1 43  ? 4.74355   -17.10813 -22.74592 1.000 11.78901  ?  124 ILE A CB   1 
ATOM   649  C CG1  . ILE A 1 43  ? 3.84411   -17.37752 -23.94051 1.000 16.24843  ?  124 ILE A CG1  1 
ATOM   650  C CG2  . ILE A 1 43  ? 6.18845   -16.88262 -23.13026 1.000 15.81992  ?  124 ILE A CG2  1 
ATOM   651  C CD1  . ILE A 1 43  ? 3.70065   -16.19436 -24.87466 1.000 19.95623  ?  124 ILE A CD1  1 
ATOM   652  H H    A ILE A 1 43  ? 2.78510   -17.66178 -21.07666 0.987 17.10653  ?  124 ILE A H    1 
ATOM   653  D D    B ILE A 1 43  ? 2.78308   -17.66311 -21.07604 0.013 17.10653  ?  124 ILE A D    1 
ATOM   654  H HA   . ILE A 1 43  ? 5.02175   -19.19149 -22.27569 1.000 16.92769  ?  124 ILE A HA   1 
ATOM   655  H HB   . ILE A 1 43  ? 4.38591   -16.19142 -22.27707 1.000 14.14682  ?  124 ILE A HB   1 
ATOM   656  H HG12 . ILE A 1 43  ? 4.26128   -18.20544 -24.51377 1.000 19.49811  ?  124 ILE A HG12 1 
ATOM   657  H HG13 . ILE A 1 43  ? 2.84955   -17.63836 -23.57872 1.000 19.49811  ?  124 ILE A HG13 1 
ATOM   658  H HG21 . ILE A 1 43  ? 6.45110   -17.56451 -23.93906 1.000 18.98391  ?  124 ILE A HG21 1 
ATOM   659  H HG22 . ILE A 1 43  ? 6.31122   -15.85078 -23.45940 1.000 18.98391  ?  124 ILE A HG22 1 
ATOM   660  H HG23 . ILE A 1 43  ? 6.82036   -17.07380 -22.26294 1.000 18.98391  ?  124 ILE A HG23 1 
ATOM   661  H HD11 . ILE A 1 43  ? 2.64729   -16.06361 -25.12254 1.000 23.94748  ?  124 ILE A HD11 1 
ATOM   662  H HD12 . ILE A 1 43  ? 4.07903   -15.30142 -24.37707 1.000 23.94748  ?  124 ILE A HD12 1 
ATOM   663  H HD13 . ILE A 1 43  ? 4.27477   -16.38624 -25.78112 1.000 23.94748  ?  124 ILE A HD13 1 
ATOM   664  N N    . PRO A 1 44  ? 6.60401   -18.78716 -20.34449 1.000 12.35285  ?  125 PRO A N    1 
ATOM   665  C CA   . PRO A 1 44  ? 7.37238   -18.65929 -19.09436 1.000 12.56966  ?  125 PRO A CA   1 
ATOM   666  C C    . PRO A 1 44  ? 8.12770   -17.34428 -19.01485 1.000 10.92001  ?  125 PRO A C    1 
ATOM   667  O O    . PRO A 1 44  ? 8.73702   -16.90528 -19.97987 1.000 12.57035  ?  125 PRO A O    1 
ATOM   668  C CB   . PRO A 1 44  ? 8.34501   -19.84555 -19.14155 1.000 14.43125  ?  125 PRO A CB   1 
ATOM   669  C CG   . PRO A 1 44  ? 8.34841   -20.31585 -20.46550 1.000 21.76629  ?  125 PRO A CG   1 
ATOM   670  C CD   . PRO A 1 44  ? 7.06450   -19.90476 -21.16617 1.000 14.50788  ?  125 PRO A CD   1 
ATOM   671  H HA   . PRO A 1 44  ? 6.70489   -18.75094 -18.23752 1.000 15.08359  ?  125 PRO A HA   1 
ATOM   672  H HB2  . PRO A 1 44  ? 9.34082   -19.50977 -18.85223 1.000 17.31750  ?  125 PRO A HB2  1 
ATOM   673  H HB3  . PRO A 1 44  ? 8.00130   -20.62366 -18.46000 1.000 17.31750  ?  125 PRO A HB3  1 
ATOM   674  H HG2  . PRO A 1 44  ? 9.20550   -19.88750 -20.98514 1.000 26.11955  ?  125 PRO A HG2  1 
ATOM   675  H HG3  . PRO A 1 44  ? 8.42765   -21.40284 -20.44885 1.000 26.11955  ?  125 PRO A HG3  1 
ATOM   676  H HD2  . PRO A 1 44  ? 7.26159   -19.58408 -22.18912 1.000 17.40945  ?  125 PRO A HD2  1 
ATOM   677  H HD3  . PRO A 1 44  ? 6.33889   -20.71815 -21.16372 1.000 17.40945  ?  125 PRO A HD3  1 
ATOM   678  N N    . THR A 1 45  ? 8.06543   -16.73489 -17.85996 1.000 11.49961  ?  126 THR A N    1 
ATOM   679  C CA   . THR A 1 45  ? 8.76529   -15.49961 -17.52698 1.000 11.77304  ?  126 THR A CA   1 
ATOM   680  C C    . THR A 1 45  ? 9.53717   -15.71868 -16.22692 1.000 11.82754  ?  126 THR A C    1 
ATOM   681  O O    . THR A 1 45  ? 9.38034   -16.72092 -15.52844 1.000 12.52702  ?  126 THR A O    1 
ATOM   682  C CB   . THR A 1 45  ? 7.81529   -14.29008 -17.35365 1.000 11.28796  ?  126 THR A CB   1 
ATOM   683  O OG1  . THR A 1 45  ? 6.85203   -14.58045 -16.32132 1.000 14.19499  ?  126 THR A OG1  1 
ATOM   684  C CG2  . THR A 1 45  ? 7.07064   -14.00867 -18.64959 1.000 15.83780  ?  126 THR A CG2  1 
ATOM   685  H H    A THR A 1 45  ? 7.50859   -17.08289 -17.07944 0.713 13.79953  ?  126 THR A H    1 
ATOM   686  D D    B THR A 1 45  ? 7.50794   -17.08458 -17.08065 0.287 13.79953  ?  126 THR A D    1 
ATOM   687  H HA   . THR A 1 45  ? 9.45102   -15.26472 -18.34104 1.000 14.12765  ?  126 THR A HA   1 
ATOM   688  H HB   . THR A 1 45  ? 8.39693   -13.40879 -17.08325 1.000 13.54555  ?  126 THR A HB   1 
ATOM   689  H HG21 . THR A 1 45  ? 6.38125   -13.17596 -18.51017 1.000 19.00536  ?  126 THR A HG21 1 
ATOM   690  H HG22 . THR A 1 45  ? 7.77836   -13.75373 -19.43841 1.000 19.00536  ?  126 THR A HG22 1 
ATOM   691  H HG23 . THR A 1 45  ? 6.50472   -14.88940 -18.95317 1.000 19.00536  ?  126 THR A HG23 1 
ATOM   692  N N    . PHE A 1 46  ? 10.40480  -14.75423 -15.92723 1.000 10.48936  ?  127 PHE A N    1 
ATOM   693  C CA   . PHE A 1 46  ? 11.13592  -14.72932 -14.66760 1.000 10.01179  ?  127 PHE A CA   1 
ATOM   694  C C    . PHE A 1 46  ? 10.37709  -13.92007 -13.63266 1.000 10.96647  ?  127 PHE A C    1 
ATOM   695  O O    . PHE A 1 46  ? 9.75311   -12.90428 -13.93978 1.000 11.92598  ?  127 PHE A O    1 
ATOM   696  C CB   . PHE A 1 46  ? 12.50593  -14.07914 -14.90556 1.000 10.28289  ?  127 PHE A CB   1 
ATOM   697  C CG   . PHE A 1 46  ? 13.52349  -15.02496 -15.42743 1.000 9.23736   ?  127 PHE A CG   1 
ATOM   698  C CD1  . PHE A 1 46  ? 13.40427  -15.58113 -16.67317 1.000 13.22844  ?  127 PHE A CD1  1 
ATOM   699  C CD2  . PHE A 1 46  ? 14.61415  -15.36154 -14.64273 1.000 10.62844  ?  127 PHE A CD2  1 
ATOM   700  C CE1  . PHE A 1 46  ? 14.35792  -16.46873 -17.15850 1.000 11.94767  ?  127 PHE A CE1  1 
ATOM   701  C CE2  . PHE A 1 46  ? 15.57834  -16.25821 -15.12901 1.000 13.48870  ?  127 PHE A CE2  1 
ATOM   702  C CZ   . PHE A 1 46  ? 15.42612  -16.81075 -16.37769 1.000 12.36550  ?  127 PHE A CZ   1 
ATOM   703  H H    A PHE A 1 46  ? 10.62290  -13.97102 -16.54320 0.644 12.58724  ?  127 PHE A H    1 
ATOM   704  D D    B PHE A 1 46  ? 10.62243  -13.97128 -16.54369 0.356 12.58724  ?  127 PHE A D    1 
ATOM   705  H HA   . PHE A 1 46  ? 11.26167  -15.74203 -14.28458 1.000 12.01415  ?  127 PHE A HA   1 
ATOM   706  H HB2  . PHE A 1 46  ? 12.39261  -13.27497 -15.63258 1.000 12.33946  ?  127 PHE A HB2  1 
ATOM   707  H HB3  . PHE A 1 46  ? 12.87454  -13.67871 -13.96116 1.000 12.33946  ?  127 PHE A HB3  1 
ATOM   708  H HD1  . PHE A 1 46  ? 12.55474  -15.32583 -17.28923 1.000 15.87413  ?  127 PHE A HD1  1 
ATOM   709  H HD2  . PHE A 1 46  ? 14.72265  -14.93410 -13.65687 1.000 12.75413  ?  127 PHE A HD2  1 
ATOM   710  H HE1  . PHE A 1 46  ? 14.25496  -16.88649 -18.14910 1.000 14.33720  ?  127 PHE A HE1  1 
ATOM   711  H HE2  . PHE A 1 46  ? 16.43618  -16.51271 -14.52424 1.000 16.18644  ?  127 PHE A HE2  1 
ATOM   712  H HZ   . PHE A 1 46  ? 16.15442  -17.51907 -16.74410 1.000 14.83860  ?  127 PHE A HZ   1 
ATOM   713  N N    . THR A 1 47  ? 10.45013  -14.37723 -12.38936 1.000 11.02526  ?  128 THR A N    1 
ATOM   714  C CA   . THR A 1 47  ? 9.85943   -13.68028 -11.23508 1.000 11.65000  ?  128 THR A CA   1 
ATOM   715  C C    . THR A 1 47  ? 10.95214  -12.87353 -10.57733 1.000 11.48821  ?  128 THR A C    1 
ATOM   716  O O    . THR A 1 47  ? 12.01803  -13.40368 -10.25050 1.000 12.88687  ?  128 THR A O    1 
ATOM   717  C CB   . THR A 1 47  ? 9.33776   -14.72168 -10.23910 1.000 14.49541  ?  128 THR A CB   1 
ATOM   718  O OG1  . THR A 1 47  ? 8.21559   -15.39897 -10.84174 1.000 18.31504  ?  128 THR A OG1  1 
ATOM   719  C CG2  . THR A 1 47  ? 8.92917   -14.04344 -8.95803  1.000 21.63036  ?  128 THR A CG2  1 
ATOM   720  H H    A THR A 1 47  ? 10.92026  -15.24593 -12.13492 0.863 13.23031  ?  128 THR A H    1 
ATOM   721  D D    B THR A 1 47  ? 10.92072  -15.24622 -12.13676 0.137 13.23031  ?  128 THR A D    1 
ATOM   722  H HA   . THR A 1 47  ? 9.04611   -13.02158 -11.53958 1.000 13.98000  ?  128 THR A HA   1 
ATOM   723  H HB   . THR A 1 47  ? 10.10629  -15.45350 -9.99031  1.000 17.39449  ?  128 THR A HB   1 
ATOM   724  H HG21 . THR A 1 47  ? 8.25284   -13.21622 -9.17343  1.000 25.95644  ?  128 THR A HG21 1 
ATOM   725  H HG22 . THR A 1 47  ? 8.42222   -14.75404 -8.30523  1.000 25.95644  ?  128 THR A HG22 1 
ATOM   726  H HG23 . THR A 1 47  ? 9.80901   -13.65637 -8.44407  1.000 25.95644  ?  128 THR A HG23 1 
ATOM   727  N N    . TRP A 1 48  ? 10.70225  -11.60048 -10.35348 1.000 10.61921  ?  129 TRP A N    1 
ATOM   728  C CA   . TRP A 1 48  ? 11.71568  -10.68451 -9.81976  1.000 10.74038  ?  129 TRP A CA   1 
ATOM   729  C C    . TRP A 1 48  ? 11.58487  -10.58595 -8.31010  1.000 11.76216  ?  129 TRP A C    1 
ATOM   730  O O    . TRP A 1 48  ? 10.54334  -10.19635 -7.78098  1.000 13.86248  ?  129 TRP A O    1 
ATOM   731  C CB   . TRP A 1 48  ? 11.56679  -9.29338  -10.44723 1.000 11.42679  ?  129 TRP A CB   1 
ATOM   732  C CG   . TRP A 1 48  ? 11.94886  -9.25148  -11.89798 1.000 10.54011  ?  129 TRP A CG   1 
ATOM   733  C CD1  . TRP A 1 48  ? 11.40451  -9.99152  -12.91470 1.000 11.87256  ?  129 TRP A CD1  1 
ATOM   734  C CD2  . TRP A 1 48  ? 12.93952  -8.42162  -12.47750 1.000 10.22308  ?  129 TRP A CD2  1 
ATOM   735  N NE1  . TRP A 1 48  ? 12.01718  -9.66539  -14.10806 1.000 11.08284  ?  129 TRP A NE1  1 
ATOM   736  C CE2  . TRP A 1 48  ? 12.93915  -8.68350  -13.86153 1.000 9.82094   ?  129 TRP A CE2  1 
ATOM   737  C CE3  . TRP A 1 48  ? 13.79561  -7.44556  -11.97031 1.000 11.49615  ?  129 TRP A CE3  1 
ATOM   738  C CZ2  . TRP A 1 48  ? 13.80511  -8.04738  -14.73680 1.000 10.81384  ?  129 TRP A CZ2  1 
ATOM   739  C CZ3  . TRP A 1 48  ? 14.65227  -6.79442  -12.83399 1.000 12.06609  ?  129 TRP A CZ3  1 
ATOM   740  C CH2  . TRP A 1 48  ? 14.66465  -7.09787  -14.20618 1.000 12.72392  ?  129 TRP A CH2  1 
ATOM   741  H H    A TRP A 1 48  ? 9.80092   -11.15669 -10.52972 0.561 12.74305  ?  129 TRP A H    1 
ATOM   742  D D    B TRP A 1 48  ? 9.80051   -11.15767 -10.53008 0.439 12.74305  ?  129 TRP A D    1 
ATOM   743  H HA   . TRP A 1 48  ? 12.70363  -11.08018 -10.05531 1.000 12.88846  ?  129 TRP A HA   1 
ATOM   744  H HB2  . TRP A 1 48  ? 10.52602  -8.97982  -10.36613 1.000 13.71215  ?  129 TRP A HB2  1 
ATOM   745  H HB3  . TRP A 1 48  ? 12.20947  -8.59465  -9.91165  1.000 13.71215  ?  129 TRP A HB3  1 
ATOM   746  H HD1  . TRP A 1 48  ? 10.61540  -10.71987 -12.79981 1.000 14.24707  ?  129 TRP A HD1  1 
ATOM   747  H HE3  . TRP A 1 48  ? 13.78851  -7.20279  -10.91797 1.000 13.79538  ?  129 TRP A HE3  1 
ATOM   748  H HZ2  . TRP A 1 48  ? 13.81014  -8.28215  -15.79096 1.000 12.97660  ?  129 TRP A HZ2  1 
ATOM   749  H HZ3  . TRP A 1 48  ? 15.32326  -6.04036  -12.44984 1.000 14.47931  ?  129 TRP A HZ3  1 
ATOM   750  H HH2  . TRP A 1 48  ? 15.35499  -6.58300  -14.85789 1.000 15.26871  ?  129 TRP A HH2  1 
ATOM   751  N N    . LEU A 1 49  ? 12.65568  -10.89167 -7.62685  1.000 10.17056  ?  130 LEU A N    1 
ATOM   752  C CA   . LEU A 1 49  ? 12.70366  -10.77759 -6.16329  1.000 10.58178  ?  130 LEU A CA   1 
ATOM   753  C C    . LEU A 1 49  ? 13.35678  -9.42149  -5.90210  1.000 11.71264  ?  130 LEU A C    1 
ATOM   754  O O    . LEU A 1 49  ? 14.54342  -9.29666  -5.58192  1.000 13.10969  ?  130 LEU A O    1 
ATOM   755  C CB   . LEU A 1 49  ? 13.48536  -11.92108 -5.50392  1.000 12.45792  ?  130 LEU A CB   1 
ATOM   756  C CG   . LEU A 1 49  ? 12.82784  -13.24516 -5.81000  1.000 16.33352  ?  130 LEU A CG   1 
ATOM   757  C CD1  . LEU A 1 49  ? 13.70948  -14.37634 -5.24436  1.000 22.88503  ?  130 LEU A CD1  1 
ATOM   758  C CD2  . LEU A 1 49  ? 11.41943  -13.38519 -5.32326  1.000 24.66001  ?  130 LEU A CD2  1 
ATOM   759  H H    A LEU A 1 49  ? 13.52445  -11.22629 -8.04358  0.985 12.20467  ?  130 LEU A H    1 
ATOM   760  D D    B LEU A 1 49  ? 13.52410  -11.22624 -8.04435  0.015 12.20467  ?  130 LEU A D    1 
ATOM   761  H HA   . LEU A 1 49  ? 11.69729  -10.82959 -5.74784  1.000 12.69814  ?  130 LEU A HA   1 
ATOM   762  H HB2  . LEU A 1 49  ? 14.50413  -11.93790 -5.89114  1.000 14.94950  ?  130 LEU A HB2  1 
ATOM   763  H HB3  . LEU A 1 49  ? 13.49954  -11.77831 -4.42341  1.000 14.94950  ?  130 LEU A HB3  1 
ATOM   764  H HG   . LEU A 1 49  ? 12.74222  -13.31610 -6.89431  1.000 19.60022  ?  130 LEU A HG   1 
ATOM   765  H HD11 . LEU A 1 49  ? 13.06826  -15.18867 -4.90222  1.000 27.46204  ?  130 LEU A HD11 1 
ATOM   766  H HD12 . LEU A 1 49  ? 14.37519  -14.73394 -6.02989  1.000 27.46204  ?  130 LEU A HD12 1 
ATOM   767  H HD13 . LEU A 1 49  ? 14.29379  -13.98756 -4.41038  1.000 27.46204  ?  130 LEU A HD13 1 
ATOM   768  H HD21 . LEU A 1 49  ? 10.79933  -12.63223 -5.80970  1.000 29.59201  ?  130 LEU A HD21 1 
ATOM   769  H HD22 . LEU A 1 49  ? 11.05593  -14.38254 -5.57079  1.000 29.59201  ?  130 LEU A HD22 1 
ATOM   770  H HD23 . LEU A 1 49  ? 11.40122  -13.24041 -4.24307  1.000 29.59201  ?  130 LEU A HD23 1 
ATOM   771  N N    . ASP A 1 50  ? 12.57532  -8.36629  -6.09565  1.000 12.85525  ?  131 ASP A N    1 
ATOM   772  C CA   . ASP A 1 50  ? 13.09002  -7.01603  -6.04091  1.000 11.59795  ?  131 ASP A CA   1 
ATOM   773  C C    . ASP A 1 50  ? 12.92435  -6.37618  -4.66921  1.000 12.94614  ?  131 ASP A C    1 
ATOM   774  O O    . ASP A 1 50  ? 13.27986  -5.21523  -4.50678  1.000 16.32646  ?  131 ASP A O    1 
ATOM   775  C CB   . ASP A 1 50  ? 12.48172  -6.16130  -7.15251  1.000 13.71106  ?  131 ASP A CB   1 
ATOM   776  C CG   . ASP A 1 50  ? 11.00122  -5.96151  -6.98336  1.000 23.63776  ?  131 ASP A CG   1 
ATOM   777  O OD1  . ASP A 1 50  ? 10.29991  -6.87465  -6.50927  1.000 19.20030  ?  131 ASP A OD1  1 
ATOM   778  O OD2  . ASP A 1 50  ? 10.53128  -4.85607  -7.30395  1.000 31.12946  -1 131 ASP A OD2  1 
ATOM   779  H H    A ASP A 1 50  ? 11.57618  -8.42203  -6.29314  0.664 15.42630  ?  131 ASP A H    1 
ATOM   780  D D    B ASP A 1 50  ? 11.57626  -8.42361  -6.29307  0.336 15.42630  ?  131 ASP A D    1 
ATOM   781  H HA   . ASP A 1 50  ? 14.16163  -7.03888  -6.23898  1.000 13.91754  ?  131 ASP A HA   1 
ATOM   782  H HB2  . ASP A 1 50  ? 12.95756  -5.18066  -7.14819  1.000 16.45327  ?  131 ASP A HB2  1 
ATOM   783  H HB3  . ASP A 1 50  ? 12.64890  -6.65257  -8.11106  1.000 16.45327  ?  131 ASP A HB3  1 
ATOM   784  N N    . SER A 1 51  ? 12.46815  -7.13117  -3.69312  1.000 14.98231  ?  132 SER A N    1 
ATOM   785  C CA   . SER A 1 51  ? 12.42924  -6.65542  -2.31090  1.000 15.46801  ?  132 SER A CA   1 
ATOM   786  C C    . SER A 1 51  ? 12.34074  -7.87264  -1.40618  1.000 15.85239  ?  132 SER A C    1 
ATOM   787  O O    . SER A 1 51  ? 11.92166  -8.95962  -1.82567  1.000 14.79439  ?  132 SER A O    1 
ATOM   788  C CB   . SER A 1 51  ? 11.24635  -5.70834  -2.05283  1.000 21.84241  ?  132 SER A CB   1 
ATOM   789  O OG   . SER A 1 51  ? 10.04015  -6.41923  -1.96854  1.000 32.58066  ?  132 SER A OG   1 
ATOM   790  H H    A SER A 1 51  ? 12.11531  -8.08024  -3.81632  0.669 17.97878  ?  132 SER A H    1 
ATOM   791  D D    B SER A 1 51  ? 12.11528  -8.08025  -3.81617  0.331 17.97878  ?  132 SER A D    1 
ATOM   792  H HA   . SER A 1 51  ? 13.34437  -6.10549  -2.09134  1.000 18.56161  ?  132 SER A HA   1 
ATOM   793  H HB2  . SER A 1 51  ? 11.41315  -5.18190  -1.11308  1.000 26.21089  ?  132 SER A HB2  1 
ATOM   794  H HB3  . SER A 1 51  ? 11.17945  -4.99409  -2.87349  1.000 26.21089  ?  132 SER A HB3  1 
ATOM   795  N N    . VAL A 1 52  ? 12.69647  -7.67119  -0.13240  1.000 14.76032  ?  133 VAL A N    1 
ATOM   796  C CA   . VAL A 1 52  ? 12.60892  -8.77841  0.82871   1.000 15.29817  ?  133 VAL A CA   1 
ATOM   797  C C    . VAL A 1 52  ? 11.16935  -9.23604  1.00968   1.000 14.31768  ?  133 VAL A C    1 
ATOM   798  O O    . VAL A 1 52  ? 10.92773  -10.39093 1.36078   1.000 16.03172  ?  133 VAL A O    1 
ATOM   799  C CB   . VAL A 1 52  ? 13.23304  -8.48519  2.21405   1.000 22.08803  ?  133 VAL A CB   1 
ATOM   800  C CG1  . VAL A 1 52  ? 14.69468  -8.49264  2.14969   1.000 23.45728  ?  133 VAL A CG1  1 
ATOM   801  C CG2  . VAL A 1 52  ? 12.76733  -7.17362  2.74915   1.000 25.88036  ?  133 VAL A CG2  1 
ATOM   802  H H    A VAL A 1 52  ? 13.03587  -6.78942  0.25189   0.658 17.71239  ?  133 VAL A H    1 
ATOM   803  D D    B VAL A 1 52  ? 13.03608  -6.79039  0.25394   0.342 17.71239  ?  133 VAL A D    1 
ATOM   804  H HA   . VAL A 1 52  ? 13.21220  -9.56789  0.38050   1.000 18.35780  ?  133 VAL A HA   1 
ATOM   805  H HB   . VAL A 1 52  ? 12.90883  -9.27508  2.89160   1.000 26.50564  ?  133 VAL A HB   1 
ATOM   806  H HG11 . VAL A 1 52  ? 15.09469  -8.46047  3.16312   1.000 28.14873  ?  133 VAL A HG11 1 
ATOM   807  H HG12 . VAL A 1 52  ? 15.02322  -9.40348  1.64914   1.000 28.14873  ?  133 VAL A HG12 1 
ATOM   808  H HG13 . VAL A 1 52  ? 15.02970  -7.61939  1.58996   1.000 28.14873  ?  133 VAL A HG13 1 
ATOM   809  H HG21 . VAL A 1 52  ? 13.28818  -6.37175  2.22589   1.000 31.05643  ?  133 VAL A HG21 1 
ATOM   810  H HG22 . VAL A 1 52  ? 11.69285  -7.08601  2.58815   1.000 31.05643  ?  133 VAL A HG22 1 
ATOM   811  H HG23 . VAL A 1 52  ? 12.98845  -7.12670  3.81546   1.000 31.05643  ?  133 VAL A HG23 1 
ATOM   812  N N    . ALA A 1 53  ? 10.20840  -8.35147  0.78596   1.000 16.15614  ?  134 ALA A N    1 
ATOM   813  C CA   . ALA A 1 53  ? 8.82282   -8.74150  0.98616   1.000 19.68203  ?  134 ALA A CA   1 
ATOM   814  C C    . ALA A 1 53  ? 8.37288   -9.82888  0.02986   1.000 19.90815  ?  134 ALA A C    1 
ATOM   815  O O    . ALA A 1 53  ? 7.37070   -10.50064 0.31486   1.000 25.33255  ?  134 ALA A O    1 
ATOM   816  C CB   . ALA A 1 53  ? 7.88922   -7.53740  0.79795   1.000 23.85701  ?  134 ALA A CB   1 
ATOM   817  H H    A ALA A 1 53  ? 10.35127  -7.39020  0.47621   0.655 19.38737  ?  134 ALA A H    1 
ATOM   818  D D    B ALA A 1 53  ? 10.34950  -7.38993  0.47623   0.345 19.38737  ?  134 ALA A D    1 
ATOM   819  H HA   . ALA A 1 53  ? 8.73661   -9.10735  2.00930   1.000 23.61844  ?  134 ALA A HA   1 
ATOM   820  H HB1  . ALA A 1 53  ? 7.03697   -7.64076  1.46958   1.000 28.62841  ?  134 ALA A HB1  1 
ATOM   821  H HB2  . ALA A 1 53  ? 8.43686   -6.62403  1.03020   1.000 28.62841  ?  134 ALA A HB2  1 
ATOM   822  H HB3  . ALA A 1 53  ? 7.54641   -7.51242  -0.23644  1.000 28.62841  ?  134 ALA A HB3  1 
ATOM   823  N N    . LYS A 1 54  ? 9.07474   -10.03304 -1.09293  1.000 16.72043  ?  135 LYS A N    1 
ATOM   824  C CA   . LYS A 1 54  ? 8.69704   -11.08203 -2.03765  1.000 16.10257  ?  135 LYS A CA   1 
ATOM   825  C C    . LYS A 1 54  ? 9.25971   -12.44617 -1.66881  1.000 15.87234  ?  135 LYS A C    1 
ATOM   826  O O    . LYS A 1 54  ? 8.89403   -13.43232 -2.32660  1.000 17.21683  ?  135 LYS A O    1 
ATOM   827  C CB   . LYS A 1 54  ? 9.12387   -10.67784 -3.42403  1.000 18.94526  ?  135 LYS A CB   1 
ATOM   828  C CG   . LYS A 1 54  ? 8.58946   -9.30349  -3.80035  1.000 28.46582  ?  135 LYS A CG   1 
ATOM   829  C CD   . LYS A 1 54  ? 8.01582   -9.29295  -5.16877  1.000 31.65439  ?  135 LYS A CD   1 
ATOM   830  C CE   . LYS A 1 54  ? 7.42313   -7.91569  -5.53282  1.000 27.42275  ?  135 LYS A CE   1 
ATOM   831  N NZ   . LYS A 1 54  ? 7.57482   -7.72597  -7.02956  1.000 36.08098  ?  135 LYS A NZ   1 
ATOM   832  H H    A LYS A 1 54  ? 9.89621   -9.49457  -1.36795  0.492 20.06452  ?  135 LYS A H    1 
ATOM   833  D D    B LYS A 1 54  ? 9.89623   -9.49469  -1.36813  0.508 20.06452  ?  135 LYS A D    1 
ATOM   834  H HA   . LYS A 1 54  ? 7.61256   -11.19102 -2.04880  1.000 19.32308  ?  135 LYS A HA   1 
ATOM   835  H HB2  . LYS A 1 54  ? 10.21246  -10.64612 -3.46965  1.000 22.73432  ?  135 LYS A HB2  1 
ATOM   836  H HB3  . LYS A 1 54  ? 8.74157   -11.40244 -4.14299  1.000 22.73432  ?  135 LYS A HB3  1 
ATOM   837  H HG2  . LYS A 1 54  ? 7.80538   -9.01766  -3.09919  1.000 34.15898  ?  135 LYS A HG2  1 
ATOM   838  H HG3  . LYS A 1 54  ? 9.40300   -8.57889  -3.76552  1.000 34.15898  ?  135 LYS A HG3  1 
ATOM   839  H HD2  . LYS A 1 54  ? 8.79959   -9.52785  -5.88893  1.000 37.98527  ?  135 LYS A HD2  1 
ATOM   840  H HD3  . LYS A 1 54  ? 7.21884   -10.03399 -5.23018  1.000 37.98527  ?  135 LYS A HD3  1 
ATOM   841  H HE2  . LYS A 1 54  ? 6.36570   -7.87975  -5.27079  1.000 32.90730  ?  135 LYS A HE2  1 
ATOM   842  H HE3  . LYS A 1 54  ? 7.96310   -7.12421  -5.01312  1.000 32.90730  ?  135 LYS A HE3  1 
ATOM   843  N N    . ILE A 1 55  ? 10.13811  -12.55820 -0.67485  1.000 13.03508  ?  136 ILE A N    1 
ATOM   844  C CA   . ILE A 1 55  ? 10.73378  -13.85538 -0.37493  1.000 14.98204  ?  136 ILE A CA   1 
ATOM   845  C C    . ILE A 1 55  ? 9.70123   -14.88876 0.03996   1.000 15.58050  ?  136 ILE A C    1 
ATOM   846  O O    . ILE A 1 55  ? 9.80982   -16.04838 -0.38360  1.000 16.42390  ?  136 ILE A O    1 
ATOM   847  C CB   . ILE A 1 55  ? 11.88924  -13.69247 0.61750   1.000 15.83085  ?  136 ILE A CB   1 
ATOM   848  C CG1  . ILE A 1 55  ? 13.02331  -12.87942 -0.04170  1.000 16.63229  ?  136 ILE A CG1  1 
ATOM   849  C CG2  . ILE A 1 55  ? 12.38528  -15.06922 1.04388   1.000 18.76847  ?  136 ILE A CG2  1 
ATOM   850  C CD1  . ILE A 1 55  ? 14.10804  -12.41169 0.90035   1.000 24.53451  ?  136 ILE A CD1  1 
ATOM   851  H H    A ILE A 1 55  ? 10.44911  -11.79302 -0.07636  0.816 15.64210  ?  136 ILE A H    1 
ATOM   852  D D    B ILE A 1 55  ? 10.45073  -11.79475 -0.07500  0.184 15.64210  ?  136 ILE A D    1 
ATOM   853  H HA   . ILE A 1 55  ? 11.17512  -14.22336 -1.30117  1.000 17.97845  ?  136 ILE A HA   1 
ATOM   854  H HB   . ILE A 1 55  ? 11.54606  -13.15401 1.50090   1.000 18.99702  ?  136 ILE A HB   1 
ATOM   855  H HG12 . ILE A 1 55  ? 13.49682  -13.50160 -0.80115  1.000 19.95874  ?  136 ILE A HG12 1 
ATOM   856  H HG13 . ILE A 1 55  ? 12.58827  -11.99328 -0.50386  1.000 19.95874  ?  136 ILE A HG13 1 
ATOM   857  H HG21 . ILE A 1 55  ? 12.47417  -15.70327 0.16174   1.000 22.52216  ?  136 ILE A HG21 1 
ATOM   858  H HG22 . ILE A 1 55  ? 13.35770  -14.96284 1.52469   1.000 22.52216  ?  136 ILE A HG22 1 
ATOM   859  H HG23 . ILE A 1 55  ? 11.67042  -15.50314 1.74301   1.000 22.52216  ?  136 ILE A HG23 1 
ATOM   860  H HD11 . ILE A 1 55  ? 14.95059  -12.04212 0.31586   1.000 29.44141  ?  136 ILE A HD11 1 
ATOM   861  H HD12 . ILE A 1 55  ? 13.71268  -11.61335 1.52839   1.000 29.44141  ?  136 ILE A HD12 1 
ATOM   862  H HD13 . ILE A 1 55  ? 14.42518  -13.25005 1.52058   1.000 29.44141  ?  136 ILE A HD13 1 
ATOM   863  N N    . PRO A 1 56  ? 8.66624   -14.56998 0.81388   1.000 15.64824  ?  137 PRO A N    1 
ATOM   864  C CA   . PRO A 1 56  ? 7.68235   -15.62132 1.11317   1.000 16.05062  ?  137 PRO A CA   1 
ATOM   865  C C    . PRO A 1 56  ? 6.94330   -16.11938 -0.12023  1.000 15.62659  ?  137 PRO A C    1 
ATOM   866  O O    . PRO A 1 56  ? 6.58816   -17.30460 -0.16172  1.000 16.14212  ?  137 PRO A O    1 
ATOM   867  C CB   . PRO A 1 56  ? 6.75547   -14.94112 2.11634   1.000 19.77162  ?  137 PRO A CB   1 
ATOM   868  C CG   . PRO A 1 56  ? 7.62685   -13.93727 2.77421   1.000 21.77673  ?  137 PRO A CG   1 
ATOM   869  C CD   . PRO A 1 56  ? 8.45366   -13.37636 1.62720   1.000 16.06061  ?  137 PRO A CD   1 
ATOM   870  H HA   . PRO A 1 56  ? 8.16340   -16.47042 1.59866   1.000 19.26074  ?  137 PRO A HA   1 
ATOM   871  H HB2  . PRO A 1 56  ? 5.92395   -14.46381 1.59782   1.000 23.72594  ?  137 PRO A HB2  1 
ATOM   872  H HB3  . PRO A 1 56  ? 6.37836   -15.66892 2.83481   1.000 23.72594  ?  137 PRO A HB3  1 
ATOM   873  H HG2  . PRO A 1 56  ? 7.02212   -13.16066 3.24249   1.000 26.13207  ?  137 PRO A HG2  1 
ATOM   874  H HG3  . PRO A 1 56  ? 8.26007   -14.41733 3.52031   1.000 26.13207  ?  137 PRO A HG3  1 
ATOM   875  H HD2  . PRO A 1 56  ? 7.90141   -12.61502 1.07630   1.000 19.27273  ?  137 PRO A HD2  1 
ATOM   876  H HD3  . PRO A 1 56  ? 9.39872   -12.96662 1.98367   1.000 19.27273  ?  137 PRO A HD3  1 
ATOM   877  N N    . ASP A 1 57  ? 6.72264   -15.26480 -1.13774  1.000 15.74389  ?  138 ASP A N    1 
ATOM   878  C CA   . ASP A 1 57  ? 6.12232   -15.72282 -2.37546  1.000 15.43271  ?  138 ASP A CA   1 
ATOM   879  C C    . ASP A 1 57  ? 7.01057   -16.74805 -3.06580  1.000 14.51172  ?  138 ASP A C    1 
ATOM   880  O O    . ASP A 1 57  ? 6.50972   -17.73240 -3.61303  1.000 14.49474  ?  138 ASP A O    1 
ATOM   881  C CB   . ASP A 1 57  ? 5.86041   -14.54082 -3.30712  1.000 19.36392  ?  138 ASP A CB   1 
ATOM   882  C CG   . ASP A 1 57  ? 4.76935   -13.61849 -2.79844  1.000 31.16487  ?  138 ASP A CG   1 
ATOM   883  O OD1  . ASP A 1 57  ? 3.87087   -14.10552 -2.10566  1.000 31.45132  ?  138 ASP A OD1  1 
ATOM   884  O OD2  . ASP A 1 57  ? 4.81261   -12.41101 -3.10943  1.000 46.61485  -1 138 ASP A OD2  1 
ATOM   885  H H    A ASP A 1 57  ? 6.94926   -14.27041 -1.12230  0.669 18.89267  ?  138 ASP A H    1 
ATOM   886  D D    B ASP A 1 57  ? 6.94830   -14.27016 -1.12481  0.331 18.89267  ?  138 ASP A D    1 
ATOM   887  H HA   . ASP A 1 57  ? 5.16521   -16.19123 -2.14600  1.000 18.51925  ?  138 ASP A HA   1 
ATOM   888  H HB2  . ASP A 1 57  ? 6.77567   -13.95704 -3.40509  1.000 23.23671  ?  138 ASP A HB2  1 
ATOM   889  H HB3  . ASP A 1 57  ? 5.55340   -14.91918 -4.28216  1.000 23.23671  ?  138 ASP A HB3  1 
ATOM   890  N N    . LEU A 1 58  ? 8.34285   -16.55990 -3.02414  1.000 15.27343  ?  139 LEU A N    1 
ATOM   891  C CA   . LEU A 1 58  ? 9.23866   -17.55833 -3.59564  1.000 14.53865  ?  139 LEU A CA   1 
ATOM   892  C C    . LEU A 1 58  ? 9.00752   -18.92720 -2.96659  1.000 12.95593  ?  139 LEU A C    1 
ATOM   893  O O    . LEU A 1 58  ? 9.00779   -19.94730 -3.64764  1.000 13.07976  ?  139 LEU A O    1 
ATOM   894  C CB   . LEU A 1 58  ? 10.67973  -17.10230 -3.43900  1.000 17.37795  ?  139 LEU A CB   1 
ATOM   895  C CG   . LEU A 1 58  ? 11.73487  -18.17053 -3.80261  1.000 17.13365  ?  139 LEU A CG   1 
ATOM   896  C CD1  . LEU A 1 58  ? 11.70863  -18.49544 -5.24606  1.000 17.13797  ?  139 LEU A CD1  1 
ATOM   897  C CD2  . LEU A 1 58  ? 13.11032  -17.70323 -3.34379  1.000 18.93417  ?  139 LEU A CD2  1 
ATOM   898  H H    A LEU A 1 58  ? 8.80856   -15.75071 -2.61339  0.658 18.32812  ?  139 LEU A H    1 
ATOM   899  D D    B LEU A 1 58  ? 8.81093   -15.75174 -2.61404  0.342 18.32812  ?  139 LEU A D    1 
ATOM   900  H HA   . LEU A 1 58  ? 9.04178   -17.65757 -4.66311  1.000 17.44638  ?  139 LEU A HA   1 
ATOM   901  H HB2  . LEU A 1 58  ? 10.84332  -16.24280 -4.08908  1.000 20.85354  ?  139 LEU A HB2  1 
ATOM   902  H HB3  . LEU A 1 58  ? 10.84206  -16.81935 -2.39896  1.000 20.85354  ?  139 LEU A HB3  1 
ATOM   903  H HG   . LEU A 1 58  ? 11.50354  -19.10165 -3.28532  1.000 20.56037  ?  139 LEU A HG   1 
ATOM   904  H HD11 . LEU A 1 58  ? 12.48502  -19.23041 -5.45854  1.000 20.56556  ?  139 LEU A HD11 1 
ATOM   905  H HD12 . LEU A 1 58  ? 10.73054  -18.90396 -5.50013  1.000 20.56556  ?  139 LEU A HD12 1 
ATOM   906  H HD13 . LEU A 1 58  ? 11.89146  -17.58572 -5.81797  1.000 20.56556  ?  139 LEU A HD13 1 
ATOM   907  H HD21 . LEU A 1 58  ? 13.12117  -17.64703 -2.25530  1.000 22.72101  ?  139 LEU A HD21 1 
ATOM   908  H HD22 . LEU A 1 58  ? 13.86001  -18.41634 -3.68666  1.000 22.72101  ?  139 LEU A HD22 1 
ATOM   909  H HD23 . LEU A 1 58  ? 13.31101  -16.71977 -3.76879  1.000 22.72101  ?  139 LEU A HD23 1 
ATOM   910  N N    . GLY A 1 59  ? 8.86341   -18.96937 -1.63299  1.000 13.11727  ?  140 GLY A N    1 
ATOM   911  C CA   . GLY A 1 59  ? 8.59906   -20.23309 -0.96783  1.000 12.97599  ?  140 GLY A CA   1 
ATOM   912  C C    . GLY A 1 59  ? 7.34417   -20.90391 -1.49036  1.000 13.46035  ?  140 GLY A C    1 
ATOM   913  O O    . GLY A 1 59  ? 7.33725   -22.11925 -1.69848  1.000 13.77131  ?  140 GLY A O    1 
ATOM   914  H H    A GLY A 1 59  ? 8.92406   -18.16343 -1.01074  0.534 15.74072  ?  140 GLY A H    1 
ATOM   915  D D    B GLY A 1 59  ? 8.92349   -18.16537 -1.00819  0.466 15.74072  ?  140 GLY A D    1 
ATOM   916  H HA2  . GLY A 1 59  ? 9.44097   -20.90735 -1.12489  1.000 15.57119  ?  140 GLY A HA2  1 
ATOM   917  H HA3  . GLY A 1 59  ? 8.47749   -20.06029 0.10150   1.000 15.57119  ?  140 GLY A HA3  1 
ATOM   918  N N    . THR A 1 60  ? 6.27365   -20.10736 -1.75210  1.000 11.57158  ?  141 THR A N    1 
ATOM   919  C CA   . THR A 1 60  ? 5.06167   -20.69774 -2.28163  1.000 11.95532  ?  141 THR A CA   1 
ATOM   920  C C    . THR A 1 60  ? 5.29355   -21.21829 -3.69356  1.000 13.22000  ?  141 THR A C    1 
ATOM   921  O O    . THR A 1 60  ? 4.73607   -22.25118 -4.07954  1.000 13.82861  ?  141 THR A O    1 
ATOM   922  C CB   . THR A 1 60  ? 3.84892   -19.75204 -2.23957  1.000 13.57279  ?  141 THR A CB   1 
ATOM   923  O OG1  . THR A 1 60  ? 4.00901   -18.65220 -3.10967  1.000 17.38768  ?  141 THR A OG1  1 
ATOM   924  C CG2  . THR A 1 60  ? 3.62126   -19.24440 -0.81128  1.000 15.24300  ?  141 THR A CG2  1 
ATOM   925  H H    A THR A 1 60  ? 6.23893   -19.09834 -1.60694  0.586 13.88590  ?  141 THR A H    1 
ATOM   926  D D    B THR A 1 60  ? 6.23647   -19.09830 -1.60782  0.414 13.88590  ?  141 THR A D    1 
ATOM   927  H HA   . THR A 1 60  ? 4.79786   -21.52603 -1.62404  1.000 14.34638  ?  141 THR A HA   1 
ATOM   928  H HB   . THR A 1 60  ? 2.97173   -20.30953 -2.56795  1.000 16.28735  ?  141 THR A HB   1 
ATOM   929  H HG21 . THR A 1 60  ? 4.43500   -18.58156 -0.51707  1.000 18.29159  ?  141 THR A HG21 1 
ATOM   930  H HG22 . THR A 1 60  ? 2.68081   -18.69612 -0.75597  1.000 18.29159  ?  141 THR A HG22 1 
ATOM   931  H HG23 . THR A 1 60  ? 3.58184   -20.08514 -0.11867  1.000 18.29159  ?  141 THR A HG23 1 
ATOM   932  N N    . TYR A 1 61  ? 6.11022   -20.52316 -4.49058  1.000 12.66198  ?  142 TYR A N    1 
ATOM   933  C CA   . TYR A 1 61  ? 6.31597   -20.95981 -5.86948  1.000 12.12461  ?  142 TYR A CA   1 
ATOM   934  C C    . TYR A 1 61  ? 7.11123   -22.25806 -5.92178  1.000 12.06933  ?  142 TYR A C    1 
ATOM   935  O O    . TYR A 1 61  ? 6.78683   -23.16830 -6.68369  1.000 12.76343  ?  142 TYR A O    1 
ATOM   936  C CB   . TYR A 1 61  ? 7.05723   -19.88778 -6.63985  1.000 14.17055  ?  142 TYR A CB   1 
ATOM   937  C CG   . TYR A 1 61  ? 6.33763   -18.59595 -6.81614  1.000 16.94044  ?  142 TYR A CG   1 
ATOM   938  C CD1  . TYR A 1 61  ? 4.95375   -18.48944 -6.61649  1.000 15.99805  ?  142 TYR A CD1  1 
ATOM   939  C CD2  . TYR A 1 61  ? 7.03713   -17.44591 -7.18291  1.000 22.73727  ?  142 TYR A CD2  1 
ATOM   940  C CE1  . TYR A 1 61  ? 4.30160   -17.30742 -6.80602  1.000 19.28326  ?  142 TYR A CE1  1 
ATOM   941  C CE2  . TYR A 1 61  ? 6.37141   -16.24644 -7.35297  1.000 31.36604  ?  142 TYR A CE2  1 
ATOM   942  C CZ   . TYR A 1 61  ? 5.01483   -16.18387 -7.15562  1.000 29.18568  ?  142 TYR A CZ   1 
ATOM   943  O OH   . TYR A 1 61  ? 4.37462   -14.97087 -7.32375  1.000 38.25648  ?  142 TYR A OH   1 
ATOM   944  H H    A TYR A 1 61  ? 6.62435   -19.68467 -4.22036  0.997 15.19438  ?  142 TYR A H    1 
ATOM   945  D D    B TYR A 1 61  ? 6.62537   -19.68453 -4.22276  0.003 15.19438  ?  142 TYR A D    1 
ATOM   946  H HA   . TYR A 1 61  ? 5.34264   -21.12349 -6.33201  1.000 14.54953  ?  142 TYR A HA   1 
ATOM   947  H HB2  . TYR A 1 61  ? 7.98592   -19.66973 -6.11251  1.000 17.00466  ?  142 TYR A HB2  1 
ATOM   948  H HB3  . TYR A 1 61  ? 7.27567   -20.27324 -7.63574  1.000 17.00466  ?  142 TYR A HB3  1 
ATOM   949  H HD1  . TYR A 1 61  ? 4.39430   -19.35982 -6.30688  1.000 19.19766  ?  142 TYR A HD1  1 
ATOM   950  H HD2  . TYR A 1 61  ? 8.10534   -17.49307 -7.33491  1.000 27.28472  ?  142 TYR A HD2  1 
ATOM   951  H HE1  . TYR A 1 61  ? 3.23008   -17.25311 -6.68235  1.000 23.13991  ?  142 TYR A HE1  1 
ATOM   952  H HE2  . TYR A 1 61  ? 6.91781   -15.36036 -7.64056  1.000 37.63925  ?  142 TYR A HE2  1 
ATOM   953  N N    . LEU A 1 62  ? 8.14037   -22.38325 -5.08975  1.000 11.94990  ?  143 LEU A N    1 
ATOM   954  C CA   . LEU A 1 62  ? 8.90421   -23.63424 -5.00125  1.000 11.76168  ?  143 LEU A CA   1 
ATOM   955  C C    . LEU A 1 62  ? 8.03305   -24.78789 -4.54185  1.000 12.70171  ?  143 LEU A C    1 
ATOM   956  O O    . LEU A 1 62  ? 8.09507   -25.89446 -5.10181  1.000 13.72801  ?  143 LEU A O    1 
ATOM   957  C CB   . LEU A 1 62  ? 10.09301  -23.46366 -4.06301  1.000 12.80846  ?  143 LEU A CB   1 
ATOM   958  C CG   . LEU A 1 62  ? 11.10466  -22.38939 -4.47284  1.000 13.52413  ?  143 LEU A CG   1 
ATOM   959  C CD1  . LEU A 1 62  ? 12.07539  -22.14979 -3.35677  1.000 18.16477  ?  143 LEU A CD1  1 
ATOM   960  C CD2  . LEU A 1 62  ? 11.86140  -22.81517 -5.71950  1.000 19.23114  ?  143 LEU A CD2  1 
ATOM   961  H H    A LEU A 1 62  ? 8.47334   -21.64796 -4.46614  0.943 14.33988  ?  143 LEU A H    1 
ATOM   962  D D    B LEU A 1 62  ? 8.47530   -21.64964 -4.46522  0.057 14.33988  ?  143 LEU A D    1 
ATOM   963  H HA   . LEU A 1 62  ? 9.28610   -23.87267 -5.99393  1.000 14.11402  ?  143 LEU A HA   1 
ATOM   964  H HB2  . LEU A 1 62  ? 9.71491   -23.19541 -3.07651  1.000 15.37015  ?  143 LEU A HB2  1 
ATOM   965  H HB3  . LEU A 1 62  ? 10.62785  -24.41205 -4.01205  1.000 15.37015  ?  143 LEU A HB3  1 
ATOM   966  H HG   . LEU A 1 62  ? 10.57054  -21.46436 -4.68995  1.000 16.22896  ?  143 LEU A HG   1 
ATOM   967  H HD11 . LEU A 1 62  ? 11.60745  -22.43018 -2.41311  1.000 21.79772  ?  143 LEU A HD11 1 
ATOM   968  H HD12 . LEU A 1 62  ? 12.96575  -22.75574 -3.52465  1.000 21.79772  ?  143 LEU A HD12 1 
ATOM   969  H HD13 . LEU A 1 62  ? 12.34267  -21.09320 -3.33963  1.000 21.79772  ?  143 LEU A HD13 1 
ATOM   970  H HD21 . LEU A 1 62  ? 11.24748  -23.51594 -6.28529  1.000 23.07736  ?  143 LEU A HD21 1 
ATOM   971  H HD22 . LEU A 1 62  ? 12.07283  -21.93362 -6.32470  1.000 23.07736  ?  143 LEU A HD22 1 
ATOM   972  H HD23 . LEU A 1 62  ? 12.79419  -23.29431 -5.42211  1.000 23.07736  ?  143 LEU A HD23 1 
ATOM   973  N N    . ALA A 1 63  ? 7.18763   -24.55491 -3.52396  1.000 12.91109  ?  144 ALA A N    1 
ATOM   974  C CA   . ALA A 1 63  ? 6.32382   -25.64707 -3.05337  1.000 13.37533  ?  144 ALA A CA   1 
ATOM   975  C C    . ALA A 1 63  ? 5.30661   -26.06456 -4.10290  1.000 12.42647  ?  144 ALA A C    1 
ATOM   976  O O    . ALA A 1 63  ? 5.01679   -27.26605 -4.25462  1.000 14.59660  ?  144 ALA A O    1 
ATOM   977  C CB   . ALA A 1 63  ? 5.62063   -25.19670 -1.75314  1.000 15.25636  ?  144 ALA A CB   1 
ATOM   978  H H    A ALA A 1 63  ? 7.08314   -23.66816 -3.03086  0.900 15.49331  ?  144 ALA A H    1 
ATOM   979  D D    B ALA A 1 63  ? 7.08132   -23.66922 -3.02933  0.100 15.49331  ?  144 ALA A D    1 
ATOM   980  H HA   . ALA A 1 63  ? 6.93572   -26.52421 -2.84286  1.000 16.05040  ?  144 ALA A HA   1 
ATOM   981  H HB1  . ALA A 1 63  ? 5.18591   -26.06866 -1.26447  1.000 18.30763  ?  144 ALA A HB1  1 
ATOM   982  H HB2  . ALA A 1 63  ? 6.35449   -24.72978 -1.09623  1.000 18.30763  ?  144 ALA A HB2  1 
ATOM   983  H HB3  . ALA A 1 63  ? 4.83703   -24.48139 -2.00295  1.000 18.30763  ?  144 ALA A HB3  1 
ATOM   984  N N    . SER A 1 64  ? 4.71772   -25.10047 -4.79007  1.000 11.72294  ?  145 SER A N    1 
ATOM   985  C CA   . SER A 1 64  ? 3.75882   -25.42037 -5.84563  1.000 13.18620  ?  145 SER A CA   1 
ATOM   986  C C    . SER A 1 64  ? 4.43570   -26.14471 -7.00997  1.000 16.00240  ?  145 SER A C    1 
ATOM   987  O O    . SER A 1 64  ? 3.86419   -27.09851 -7.57868  1.000 16.01308  ?  145 SER A O    1 
ATOM   988  C CB   . SER A 1 64  ? 3.08622   -24.15931 -6.37988  1.000 13.58669  ?  145 SER A CB   1 
ATOM   989  O OG   . SER A 1 64  ? 2.37797   -23.47673 -5.33827  1.000 16.47994  ?  145 SER A OG   1 
ATOM   990  H H    A SER A 1 64  ? 4.87518   -24.10270 -4.64845  0.670 14.06752  ?  145 SER A H    1 
ATOM   991  D D    B SER A 1 64  ? 4.87344   -24.10215 -4.65040  0.330 14.06752  ?  145 SER A D    1 
ATOM   992  H HA   . SER A 1 64  ? 2.99530   -26.06281 -5.40700  1.000 15.82344  ?  145 SER A HA   1 
ATOM   993  H HB2  . SER A 1 64  ? 3.84962   -23.49448 -6.78401  1.000 16.30403  ?  145 SER A HB2  1 
ATOM   994  H HB3  . SER A 1 64  ? 2.38187   -24.43814 -7.16362  1.000 16.30403  ?  145 SER A HB3  1 
ATOM   995  N N    . ALA A 1 65  ? 5.64882   -25.69928 -7.38606  1.000 12.55507  ?  146 ALA A N    1 
ATOM   996  C CA   . ALA A 1 65  ? 6.38615   -26.38170 -8.42809  1.000 14.22251  ?  146 ALA A CA   1 
ATOM   997  C C    . ALA A 1 65  ? 6.71941   -27.80052 -8.01707  1.000 13.56500  ?  146 ALA A C    1 
ATOM   998  O O    . ALA A 1 65  ? 6.54981   -28.72819 -8.82377  1.000 14.10851  ?  146 ALA A O    1 
ATOM   999  C CB   . ALA A 1 65  ? 7.67008   -25.59872 -8.74677  1.000 12.43938  ?  146 ALA A CB   1 
ATOM   1000 H H    A ALA A 1 65  ? 6.12316   -24.88806 -6.98942  1.000 15.06608  ?  146 ALA A H    1 
ATOM   1001 D D    B ALA A 1 65  ? 6.12523   -24.88847 -6.99106  0.000 15.06608  ?  146 ALA A D    1 
ATOM   1002 H HA   . ALA A 1 65  ? 5.77654   -26.42513 -9.33063  1.000 17.06702  ?  146 ALA A HA   1 
ATOM   1003 H HB1  . ALA A 1 65  ? 8.28263   -26.18519 -9.43155  1.000 14.92725  ?  146 ALA A HB1  1 
ATOM   1004 H HB2  . ALA A 1 65  ? 7.40104   -24.64902 -9.20914  1.000 14.92725  ?  146 ALA A HB2  1 
ATOM   1005 H HB3  . ALA A 1 65  ? 8.21574   -25.41971 -7.82032  1.000 14.92725  ?  146 ALA A HB3  1 
ATOM   1006 N N    . SER A 1 66  ? 7.12998   -28.01703 -6.75996  1.000 12.98690  ?  147 SER A N    1 
ATOM   1007 C CA   . SER A 1 66  ? 7.45098   -29.36587 -6.30574  1.000 13.18996  ?  147 SER A CA   1 
ATOM   1008 C C    . SER A 1 66  ? 6.22849   -30.27227 -6.44252  1.000 15.89093  ?  147 SER A C    1 
ATOM   1009 O O    . SER A 1 66  ? 6.31277   -31.39923 -6.95641  1.000 17.07532  ?  147 SER A O    1 
ATOM   1010 C CB   . SER A 1 66  ? 7.91427   -29.29506 -4.84608  1.000 14.18243  ?  147 SER A CB   1 
ATOM   1011 O OG   . SER A 1 66  ? 8.20118   -30.59848 -4.36901  1.000 19.15398  ?  147 SER A OG   1 
ATOM   1012 H H    A SER A 1 66  ? 7.24633   -27.29250 -6.05150  0.761 15.58428  ?  147 SER A H    1 
ATOM   1013 D D    B SER A 1 66  ? 7.24703   -27.29415 -6.04993  0.239 15.58428  ?  147 SER A D    1 
ATOM   1014 H HA   . SER A 1 66  ? 8.25656   -29.78690 -6.90729  1.000 15.82795  ?  147 SER A HA   1 
ATOM   1015 H HB2  . SER A 1 66  ? 8.81435   -28.68343 -4.78399  1.000 17.01892  ?  147 SER A HB2  1 
ATOM   1016 H HB3  . SER A 1 66  ? 7.12269   -28.85622 -4.23868  1.000 17.01892  ?  147 SER A HB3  1 
ATOM   1017 N N    . ALA A 1 67  ? 5.06382   -29.78610 -6.03032  1.000 14.79786  ?  148 ALA A N    1 
ATOM   1018 C CA   . ALA A 1 67  ? 3.88010   -30.63081 -6.07433  1.000 15.66090  ?  148 ALA A CA   1 
ATOM   1019 C C    . ALA A 1 67  ? 3.45518   -30.88383 -7.50510  1.000 16.33045  ?  148 ALA A C    1 
ATOM   1020 O O    . ALA A 1 67  ? 3.04355   -32.00754 -7.84709  1.000 18.60182  ?  148 ALA A O    1 
ATOM   1021 C CB   . ALA A 1 67  ? 2.74251   -29.95529 -5.29067  1.000 17.26827  ?  148 ALA A CB   1 
ATOM   1022 H H    A ALA A 1 67  ? 4.91158   -28.84319 -5.67235  0.513 17.75743  ?  148 ALA A H    1 
ATOM   1023 D D    B ALA A 1 67  ? 4.90905   -28.84373 -5.67201  0.487 17.75743  ?  148 ALA A D    1 
ATOM   1024 H HA   . ALA A 1 67  ? 4.10000   -31.59076 -5.60717  1.000 18.79308  ?  148 ALA A HA   1 
ATOM   1025 H HB1  . ALA A 1 67  ? 3.08765   -29.73921 -4.27958  1.000 20.72192  ?  148 ALA A HB1  1 
ATOM   1026 H HB2  . ALA A 1 67  ? 2.46544   -29.02938 -5.79468  1.000 20.72192  ?  148 ALA A HB2  1 
ATOM   1027 H HB3  . ALA A 1 67  ? 1.88685   -30.62960 -5.25519  1.000 20.72192  ?  148 ALA A HB3  1 
ATOM   1028 N N    . LEU A 1 68  ? 3.49281   -29.85448 -8.35948  1.000 15.53185  ?  149 LEU A N    1 
ATOM   1029 C CA   . LEU A 1 68  ? 3.14648   -30.05450 -9.76912  1.000 15.97579  ?  149 LEU A CA   1 
ATOM   1030 C C    . LEU A 1 68  ? 4.05228   -31.11405 -10.39127 1.000 17.66265  ?  149 LEU A C    1 
ATOM   1031 O O    . LEU A 1 68  ? 3.58983   -31.95167 -11.17169 1.000 19.25372  ?  149 LEU A O    1 
ATOM   1032 C CB   . LEU A 1 68  ? 3.25560   -28.73074 -10.50937 1.000 17.01080  ?  149 LEU A CB   1 
ATOM   1033 C CG   . LEU A 1 68  ? 2.88618   -28.77260 -12.00437 1.000 25.39077  ?  149 LEU A CG   1 
ATOM   1034 C CD1  . LEU A 1 68  ? 1.42034   -29.13482 -12.19922 1.000 26.38118  ?  149 LEU A CD1  1 
ATOM   1035 C CD2  . LEU A 1 68  ? 3.18925   -27.43220 -12.64226 1.000 21.42818  ?  149 LEU A CD2  1 
ATOM   1036 H H    A LEU A 1 68  ? 3.75121   -28.89872 -8.11423  0.732 18.63822  ?  149 LEU A H    1 
ATOM   1037 D D    B LEU A 1 68  ? 3.75082   -28.89797 -8.11676  0.268 18.63822  ?  149 LEU A D    1 
ATOM   1038 H HA   . LEU A 1 68  ? 2.11605   -30.39882 -9.85723  1.000 19.17095  ?  149 LEU A HA   1 
ATOM   1039 H HB2  . LEU A 1 68  ? 2.58798   -28.01497 -10.02973 1.000 20.41297  ?  149 LEU A HB2  1 
ATOM   1040 H HB3  . LEU A 1 68  ? 4.28656   -28.38392 -10.43912 1.000 20.41297  ?  149 LEU A HB3  1 
ATOM   1041 H HG   . LEU A 1 68  ? 3.48045   -29.54233 -12.49677 1.000 30.46892  ?  149 LEU A HG   1 
ATOM   1042 H HD11 . LEU A 1 68  ? 1.34855   -29.94637 -12.92333 1.000 31.65742  ?  149 LEU A HD11 1 
ATOM   1043 H HD12 . LEU A 1 68  ? 1.00297   -29.45152 -11.24339 1.000 31.65742  ?  149 LEU A HD12 1 
ATOM   1044 H HD13 . LEU A 1 68  ? 0.88447   -28.25987 -12.56718 1.000 31.65742  ?  149 LEU A HD13 1 
ATOM   1045 H HD21 . LEU A 1 68  ? 3.36139   -27.57753 -13.70872 1.000 25.71382  ?  149 LEU A HD21 1 
ATOM   1046 H HD22 . LEU A 1 68  ? 2.33955   -26.76662 -12.49021 1.000 25.71382  ?  149 LEU A HD22 1 
ATOM   1047 H HD23 . LEU A 1 68  ? 4.07975   -27.01058 -12.17607 1.000 25.71382  ?  149 LEU A HD23 1 
ATOM   1048 N N    . GLY A 1 69  ? 5.34273   -31.09622 -10.04631 1.000 15.56078  ?  150 GLY A N    1 
ATOM   1049 C CA   . GLY A 1 69  ? 6.25659   -32.10042 -10.53261 1.000 17.37743  ?  150 GLY A CA   1 
ATOM   1050 C C    . GLY A 1 69  ? 5.79152   -33.49857 -10.19508 1.000 23.36688  ?  150 GLY A C    1 
ATOM   1051 O O    . GLY A 1 69  ? 5.67680   -34.35147 -11.07819 1.000 22.14913  ?  150 GLY A O    1 
ATOM   1052 H H    A GLY A 1 69  ? 5.77174   -30.40056 -9.43605  0.741 18.67294  ?  150 GLY A H    1 
ATOM   1053 D D    B GLY A 1 69  ? 5.77474   -30.40212 -9.43640  0.259 18.67294  ?  150 GLY A D    1 
ATOM   1054 H HA2  . GLY A 1 69  ? 6.34383   -32.01731 -11.61593 1.000 20.85291  ?  150 GLY A HA2  1 
ATOM   1055 H HA3  . GLY A 1 69  ? 7.23806   -31.94510 -10.08461 1.000 20.85291  ?  150 GLY A HA3  1 
ATOM   1056 N N    . LYS A 1 70  ? 5.52791   -33.75857 -8.91625  1.000 20.91653  ?  151 LYS A N    1 
ATOM   1057 C CA   . LYS A 1 70  ? 5.02303   -35.07638 -8.50230  1.000 22.65247  ?  151 LYS A CA   1 
ATOM   1058 C C    . LYS A 1 70  ? 3.70258   -35.41260 -9.18073  1.000 24.54119  ?  151 LYS A C    1 
ATOM   1059 O O    . LYS A 1 70  ? 3.52489   -36.53387 -9.66964  1.000 36.05810  ?  151 LYS A O    1 
ATOM   1060 C CB   . LYS A 1 70  ? 4.91089   -35.12269 -6.98204  1.000 27.11964  ?  151 LYS A CB   1 
ATOM   1061 C CG   . LYS A 1 70  ? 6.24635   -34.92881 -6.27983  1.000 25.12959  ?  151 LYS A CG   1 
ATOM   1062 C CD   . LYS A 1 70  ? 6.11007   -35.04058 -4.76292  1.000 43.56114  ?  151 LYS A CD   1 
ATOM   1063 C CE   . LYS A 1 70  ? 7.46144   -35.18533 -4.05344  1.000 65.73064  ?  151 LYS A CE   1 
ATOM   1064 N NZ   . LYS A 1 70  ? 8.07733   -33.87805 -3.66203  1.000 81.36512  ?  151 LYS A NZ   1 
ATOM   1065 H H    A LYS A 1 70  ? 5.64867   -33.09520 -8.15091  0.832 25.09983  ?  151 LYS A H    1 
ATOM   1066 D D    B LYS A 1 70  ? 5.64780   -33.09707 -8.14915  0.168 25.09983  ?  151 LYS A D    1 
ATOM   1067 H HA   . LYS A 1 70  ? 5.73184   -35.84689 -8.80560  1.000 27.18296  ?  151 LYS A HA   1 
ATOM   1068 H HB2  . LYS A 1 70  ? 4.23977   -34.32938 -6.65287  1.000 32.54356  ?  151 LYS A HB2  1 
ATOM   1069 H HB3  . LYS A 1 70  ? 4.51357   -36.09370 -6.68642  1.000 32.54356  ?  151 LYS A HB3  1 
ATOM   1070 H HG2  . LYS A 1 70  ? 6.94485   -35.69461 -6.61709  1.000 30.15551  ?  151 LYS A HG2  1 
ATOM   1071 H HG3  . LYS A 1 70  ? 6.63644   -33.93864 -6.51541  1.000 30.15551  ?  151 LYS A HG3  1 
ATOM   1072 H HD2  . LYS A 1 70  ? 5.62515   -34.14157 -4.38249  1.000 52.27337  ?  151 LYS A HD2  1 
ATOM   1073 H HD3  . LYS A 1 70  ? 5.50908   -35.91793 -4.52382  1.000 52.27337  ?  151 LYS A HD3  1 
ATOM   1074 H HE2  . LYS A 1 70  ? 7.32080   -35.77175 -3.14546  1.000 78.87677  ?  151 LYS A HE2  1 
ATOM   1075 H HE3  . LYS A 1 70  ? 8.15665   -35.69362 -4.72159  1.000 78.87677  ?  151 LYS A HE3  1 
ATOM   1076 N N    . SER A 1 71  ? 2.80809   -34.44707 -9.30919  1.000 23.04475  ?  152 SER A N    1 
ATOM   1077 C CA   . SER A 1 71  ? 1.51068   -34.73499 -9.90420  1.000 32.37506  ?  152 SER A CA   1 
ATOM   1078 C C    . SER A 1 71  ? 1.62399   -35.15949 -11.36251 1.000 43.39836  ?  152 SER A C    1 
ATOM   1079 O O    . SER A 1 71  ? 0.75194   -35.87789 -11.86559 1.000 34.35421  ?  152 SER A O    1 
ATOM   1080 C CB   . SER A 1 71  ? 0.58827   -33.50603 -9.83613  1.000 26.28800  ?  152 SER A CB   1 
ATOM   1081 O OG   . SER A 1 71  ? 0.32613   -33.15908 -8.48533  1.000 43.77155  ?  152 SER A OG   1 
ATOM   1082 H H    A SER A 1 71  ? 2.94347   -33.47837 -9.01988  0.852 27.65370  ?  152 SER A H    1 
ATOM   1083 D D    B SER A 1 71  ? 2.94103   -33.47778 -9.02073  0.148 27.65370  ?  152 SER A D    1 
ATOM   1084 H HA   . SER A 1 71  ? 1.07115   -35.54679 -9.32463  1.000 38.85007  ?  152 SER A HA   1 
ATOM   1085 H HB2  . SER A 1 71  ? 1.07517   -32.66643 -10.33223 1.000 31.54560  ?  152 SER A HB2  1 
ATOM   1086 H HB3  . SER A 1 71  ? -0.35310  -33.73833 -10.33409 1.000 31.54560  ?  152 SER A HB3  1 
ATOM   1087 N N    . THR A 1 72  ? 2.65162   -34.69940 -12.07485 1.000 30.24689  ?  153 THR A N    1 
ATOM   1088 C CA   . THR A 1 72  ? 2.71154   -34.88173 -13.51977 1.000 22.12168  ?  153 THR A CA   1 
ATOM   1089 C C    . THR A 1 72  ? 3.87099   -35.74793 -13.96309 1.000 23.04525  ?  153 THR A C    1 
ATOM   1090 O O    . THR A 1 72  ? 3.99709   -36.00921 -15.16373 1.000 31.36238  ?  153 THR A O    1 
ATOM   1091 C CB   . THR A 1 72  ? 2.74327   -33.52465 -14.23276 1.000 33.38772  ?  153 THR A CB   1 
ATOM   1092 O OG1  . THR A 1 72  ? 3.91454   -32.80078 -13.82357 1.000 25.22380  ?  153 THR A OG1  1 
ATOM   1093 C CG2  . THR A 1 72  ? 1.48570   -32.71599 -13.90308 1.000 24.79199  ?  153 THR A CG2  1 
ATOM   1094 H H    A THR A 1 72  ? 3.44943   -34.20102 -11.68050 0.750 36.29627  ?  153 THR A H    1 
ATOM   1095 D D    B THR A 1 72  ? 3.44900   -34.20111 -11.67952 0.250 36.29627  ?  153 THR A D    1 
ATOM   1096 H HA   . THR A 1 72  ? 1.80092   -35.38313 -13.84757 1.000 26.54602  ?  153 THR A HA   1 
ATOM   1097 H HB   . THR A 1 72  ? 2.77201   -33.67274 -15.31227 1.000 40.06526  ?  153 THR A HB   1 
ATOM   1098 H HG21 . THR A 1 72  ? 0.96983   -33.15958 -13.05150 1.000 29.75038  ?  153 THR A HG21 1 
ATOM   1099 H HG22 . THR A 1 72  ? 1.75657   -31.68927 -13.65695 1.000 29.75038  ?  153 THR A HG22 1 
ATOM   1100 H HG23 . THR A 1 72  ? 0.81208   -32.70839 -14.75998 1.000 29.75038  ?  153 THR A HG23 1 
ATOM   1101 N N    . GLY A 1 73  ? 4.66923   -36.24576 -13.03570 1.000 28.85438  ?  154 GLY A N    1 
ATOM   1102 C CA   . GLY A 1 73  ? 5.85877   -37.00308 -13.36875 1.000 31.23190  ?  154 GLY A CA   1 
ATOM   1103 C C    . GLY A 1 73  ? 6.93135   -36.19503 -14.05347 1.000 36.89905  ?  154 GLY A C    1 
ATOM   1104 O O    . GLY A 1 73  ? 7.71971   -36.75177 -14.82425 1.000 30.72598  ?  154 GLY A O    1 
ATOM   1105 H H    A GLY A 1 73  ? 4.51828   -36.14099 -12.03239 0.584 34.62526  ?  154 GLY A H    1 
ATOM   1106 D D    B GLY A 1 73  ? 4.51961   -36.14183 -12.03210 0.416 34.62526  ?  154 GLY A D    1 
ATOM   1107 H HA2  . GLY A 1 73  ? 6.28213   -37.41546 -12.45288 1.000 37.47828  ?  154 GLY A HA2  1 
ATOM   1108 H HA3  . GLY A 1 73  ? 5.58094   -37.82253 -14.03163 1.000 37.47828  ?  154 GLY A HA3  1 
ATOM   1109 N N    . THR A 1 74  ? 6.98293   -34.89955 -13.80833 1.000 26.72896  ?  155 THR A N    1 
ATOM   1110 C CA   . THR A 1 74  ? 7.97850   -34.03686 -14.43955 1.000 21.75317  ?  155 THR A CA   1 
ATOM   1111 C C    . THR A 1 74  ? 8.89361   -33.44507 -13.37138 1.000 20.68030  ?  155 THR A C    1 
ATOM   1112 O O    . THR A 1 74  ? 8.63571   -33.52118 -12.17067 1.000 23.56652  ?  155 THR A O    1 
ATOM   1113 C CB   . THR A 1 74  ? 7.29609   -32.89399 -15.18993 1.000 21.99176  ?  155 THR A CB   1 
ATOM   1114 O OG1  . THR A 1 74  ? 6.46495   -32.15777 -14.27071 1.000 22.90137  ?  155 THR A OG1  1 
ATOM   1115 C CG2  . THR A 1 74  ? 6.46702   -33.42422 -16.32386 1.000 29.02421  ?  155 THR A CG2  1 
ATOM   1116 H H    A THR A 1 74  ? 6.34912   -34.41091 -13.17594 0.868 32.07475  ?  155 THR A H    1 
ATOM   1117 D D    B THR A 1 74  ? 6.34799   -34.41299 -13.17547 0.132 32.07475  ?  155 THR A D    1 
ATOM   1118 H HA   . THR A 1 74  ? 8.57452   -34.62646 -15.13614 1.000 26.10380  ?  155 THR A HA   1 
ATOM   1119 H HB   . THR A 1 74  ? 8.04600   -32.22632 -15.61416 1.000 26.39011  ?  155 THR A HB   1 
ATOM   1120 H HG21 . THR A 1 74  ? 7.09513   -33.98937 -17.01247 1.000 34.82905  ?  155 THR A HG21 1 
ATOM   1121 H HG22 . THR A 1 74  ? 5.68515   -34.07924 -15.93952 1.000 34.82905  ?  155 THR A HG22 1 
ATOM   1122 H HG23 . THR A 1 74  ? 6.00321   -32.59901 -16.86424 1.000 34.82905  ?  155 THR A HG23 1 
ATOM   1123 N N    . LYS A 1 75  ? 9.99320   -32.88547 -13.83736 1.000 15.88827  ?  156 LYS A N    1 
ATOM   1124 C CA   . LYS A 1 75  ? 10.90145  -32.10236 -13.02377 1.000 16.37764  ?  156 LYS A CA   1 
ATOM   1125 C C    . LYS A 1 75  ? 10.67151  -30.63527 -13.37970 1.000 15.52854  ?  156 LYS A C    1 
ATOM   1126 O O    . LYS A 1 75  ? 10.66987  -30.27180 -14.56618 1.000 15.77033  ?  156 LYS A O    1 
ATOM   1127 C CB   . LYS A 1 75  ? 12.33825  -32.50974 -13.34570 1.000 22.80694  ?  156 LYS A CB   1 
ATOM   1128 C CG   . LYS A 1 75  ? 12.63654  -33.95573 -13.03028 1.000 30.96211  ?  156 LYS A CG   1 
ATOM   1129 C CD   . LYS A 1 75  ? 14.13638  -34.28257 -13.00864 1.000 45.24961  ?  156 LYS A CD   1 
ATOM   1130 C CE   . LYS A 1 75  ? 14.71738  -34.41434 -14.42869 1.000 71.42068  ?  156 LYS A CE   1 
ATOM   1131 N NZ   . LYS A 1 75  ? 14.26893  -35.66010 -15.12255 1.000 106.48303 ?  156 LYS A NZ   1 
ATOM   1132 H H    A LYS A 1 75  ? 10.29297  -32.95920 -14.80952 0.588 19.06593  ?  156 LYS A H    1 
ATOM   1133 D D    B LYS A 1 75  ? 10.29142  -32.96028 -14.80992 0.412 19.06593  ?  156 LYS A D    1 
ATOM   1134 H HA   . LYS A 1 75  ? 10.72973  -32.24722 -11.95717 1.000 19.65317  ?  156 LYS A HA   1 
ATOM   1135 H HB2  . LYS A 1 75  ? 12.51774  -32.35558 -14.40971 1.000 27.36833  ?  156 LYS A HB2  1 
ATOM   1136 H HB3  . LYS A 1 75  ? 13.01884  -31.89225 -12.75952 1.000 27.36833  ?  156 LYS A HB3  1 
ATOM   1137 H HG2  . LYS A 1 75  ? 12.23018  -34.19275 -12.04703 1.000 37.15454  ?  156 LYS A HG2  1 
ATOM   1138 H HG3  . LYS A 1 75  ? 12.16983  -34.58498 -13.78813 1.000 37.15454  ?  156 LYS A HG3  1 
ATOM   1139 H HD2  . LYS A 1 75  ? 14.67072  -33.48334 -12.49502 1.000 54.29953  ?  156 LYS A HD2  1 
ATOM   1140 H HD3  . LYS A 1 75  ? 14.29041  -35.22811 -12.48871 1.000 54.29953  ?  156 LYS A HD3  1 
ATOM   1141 H HE2  . LYS A 1 75  ? 14.39458  -33.56132 -15.02556 1.000 85.70482  ?  156 LYS A HE2  1 
ATOM   1142 H HE3  . LYS A 1 75  ? 15.80543  -34.43592 -14.36717 1.000 85.70482  ?  156 LYS A HE3  1 
ATOM   1143 N N    . GLN A 1 76  ? 10.48017  -29.79994 -12.36326 1.000 14.48600  ?  157 GLN A N    1 
ATOM   1144 C CA   . GLN A 1 76  ? 10.08304  -28.42379 -12.56837 1.000 11.32725  ?  157 GLN A CA   1 
ATOM   1145 C C    . GLN A 1 76  ? 11.25083  -27.48014 -12.28466 1.000 13.64629  ?  157 GLN A C    1 
ATOM   1146 O O    . GLN A 1 76  ? 12.14585  -27.77351 -11.47903 1.000 13.28540  ?  157 GLN A O    1 
ATOM   1147 C CB   . GLN A 1 76  ? 8.93074   -28.04858 -11.66494 1.000 13.54800  ?  157 GLN A CB   1 
ATOM   1148 C CG   . GLN A 1 76  ? 7.67363   -28.84576 -11.88814 1.000 16.04473  ?  157 GLN A CG   1 
ATOM   1149 C CD   . GLN A 1 76  ? 6.92506   -28.40752 -13.07886 1.000 17.31028  ?  157 GLN A CD   1 
ATOM   1150 O OE1  . GLN A 1 76  ? 6.73592   -27.22929 -13.31009 1.000 19.40382  ?  157 GLN A OE1  1 
ATOM   1151 N NE2  . GLN A 1 76  ? 6.43922   -29.37786 -13.87051 1.000 21.43790  ?  157 GLN A NE2  1 
ATOM   1152 H H    A GLN A 1 76  ? 10.59531  -30.05663 -11.38282 0.826 17.38321  ?  157 GLN A H    1 
ATOM   1153 D D    B GLN A 1 76  ? 10.59585  -30.05861 -11.38341 0.174 17.38321  ?  157 GLN A D    1 
ATOM   1154 H HA   . GLN A 1 76  ? 9.77680   -28.30055 -13.60718 1.000 13.59270  ?  157 GLN A HA   1 
ATOM   1155 H HB2  . GLN A 1 76  ? 9.23751   -28.20151 -10.63024 1.000 16.25761  ?  157 GLN A HB2  1 
ATOM   1156 H HB3  . GLN A 1 76  ? 8.68802   -26.99893 -11.83056 1.000 16.25761  ?  157 GLN A HB3  1 
ATOM   1157 H HG2  . GLN A 1 76  ? 7.93742   -29.89473 -12.02300 1.000 19.25368  ?  157 GLN A HG2  1 
ATOM   1158 H HG3  . GLN A 1 76  ? 7.02309   -28.73348 -11.02080 1.000 19.25368  ?  157 GLN A HG3  1 
ATOM   1159 N N    . LEU A 1 77  ? 11.22953  -26.34444 -12.97290 1.000 11.90659  ?  158 LEU A N    1 
ATOM   1160 C CA   . LEU A 1 77  ? 12.27967  -25.33628 -12.93010 1.000 10.98912  ?  158 LEU A CA   1 
ATOM   1161 C C    . LEU A 1 77  ? 11.63390  -23.98842 -12.69451 1.000 11.98512  ?  158 LEU A C    1 
ATOM   1162 O O    . LEU A 1 77  ? 10.66406  -23.61944 -13.37402 1.000 12.66929  ?  158 LEU A O    1 
ATOM   1163 C CB   . LEU A 1 77  ? 13.05631  -25.37455 -14.24383 1.000 11.79215  ?  158 LEU A CB   1 
ATOM   1164 C CG   . LEU A 1 77  ? 14.24012  -24.43948 -14.46527 1.000 12.11502  ?  158 LEU A CG   1 
ATOM   1165 C CD1  . LEU A 1 77  ? 15.07988  -25.06949 -15.58649 1.000 15.47511  ?  158 LEU A CD1  1 
ATOM   1166 C CD2  . LEU A 1 77  ? 13.89800  -23.04901 -14.83244 1.000 13.57105  ?  158 LEU A CD2  1 
ATOM   1167 H H    A LEU A 1 77  ? 10.46459  -26.08418 -13.59542 0.947 14.28791  ?  158 LEU A H    1 
ATOM   1168 D D    B LEU A 1 77  ? 10.46365  -26.08589 -13.59498 0.053 14.28791  ?  158 LEU A D    1 
ATOM   1169 H HA   . LEU A 1 77  ? 12.97816  -25.50371 -12.11024 1.000 13.18694  ?  158 LEU A HA   1 
ATOM   1170 H HB2  . LEU A 1 77  ? 13.44590  -26.38628 -14.35661 1.000 14.15058  ?  158 LEU A HB2  1 
ATOM   1171 H HB3  . LEU A 1 77  ? 12.34678  -25.15713 -15.04220 1.000 14.15058  ?  158 LEU A HB3  1 
ATOM   1172 H HG   . LEU A 1 77  ? 14.77326  -24.33824 -13.51996 1.000 14.53802  ?  158 LEU A HG   1 
ATOM   1173 H HD11 . LEU A 1 77  ? 14.43263  -25.28395 -16.43689 1.000 18.57014  ?  158 LEU A HD11 1 
ATOM   1174 H HD12 . LEU A 1 77  ? 15.86102  -24.36878 -15.88131 1.000 18.57014  ?  158 LEU A HD12 1 
ATOM   1175 H HD13 . LEU A 1 77  ? 15.52802  -25.99241 -15.21840 1.000 18.57014  ?  158 LEU A HD13 1 
ATOM   1176 H HD21 . LEU A 1 77  ? 13.61182  -23.01977 -15.88379 1.000 16.28526  ?  158 LEU A HD21 1 
ATOM   1177 H HD22 . LEU A 1 77  ? 13.06777  -22.71210 -14.21171 1.000 16.28526  ?  158 LEU A HD22 1 
ATOM   1178 H HD23 . LEU A 1 77  ? 14.76804  -22.41378 -14.66624 1.000 16.28526  ?  158 LEU A HD23 1 
ATOM   1179 N N    . VAL A 1 78  ? 12.15021  -23.26594 -11.71253 1.000 11.23964  ?  159 VAL A N    1 
ATOM   1180 C CA   . VAL A 1 78  ? 11.65796  -21.93616 -11.33831 1.000 10.09387  ?  159 VAL A CA   1 
ATOM   1181 C C    . VAL A 1 78  ? 12.71086  -20.90372 -11.73772 1.000 11.29942  ?  159 VAL A C    1 
ATOM   1182 O O    . VAL A 1 78  ? 13.90076  -21.05887 -11.41104 1.000 11.67980  ?  159 VAL A O    1 
ATOM   1183 C CB   . VAL A 1 78  ? 11.33683  -21.87676 -9.83791  1.000 11.14270  ?  159 VAL A CB   1 
ATOM   1184 C CG1  . VAL A 1 78  ? 11.01542  -20.47955 -9.39354  1.000 15.25534  ?  159 VAL A CG1  1 
ATOM   1185 C CG2  . VAL A 1 78  ? 10.17087  -22.81939 -9.52893  1.000 13.59781  ?  159 VAL A CG2  1 
ATOM   1186 H H    A VAL A 1 78  ? 12.93281  -23.57785 -11.13751 1.000 13.48756  ?  159 VAL A H    1 
ATOM   1187 D D    B VAL A 1 78  ? 12.93291  -23.58023 -11.13895 0.000 13.48756  ?  159 VAL A D    1 
ATOM   1188 H HA   . VAL A 1 78  ? 10.74706  -21.70478 -11.89042 1.000 12.11265  ?  159 VAL A HA   1 
ATOM   1189 H HB   . VAL A 1 78  ? 12.21705  -22.19442 -9.27898  1.000 13.37124  ?  159 VAL A HB   1 
ATOM   1190 H HG11 . VAL A 1 78  ? 11.82865  -19.81701 -9.68985  1.000 18.30640  ?  159 VAL A HG11 1 
ATOM   1191 H HG12 . VAL A 1 78  ? 10.08609  -20.16176 -9.86625  1.000 18.30640  ?  159 VAL A HG12 1 
ATOM   1192 H HG13 . VAL A 1 78  ? 10.90355  -20.46887 -8.30935  1.000 18.30640  ?  159 VAL A HG13 1 
ATOM   1193 H HG21 . VAL A 1 78  ? 10.15610  -23.02671 -8.45893  1.000 16.31737  ?  159 VAL A HG21 1 
ATOM   1194 H HG22 . VAL A 1 78  ? 9.23847   -22.34029 -9.82761  1.000 16.31737  ?  159 VAL A HG22 1 
ATOM   1195 H HG23 . VAL A 1 78  ? 10.30716  -23.74669 -10.08538 1.000 16.31737  ?  159 VAL A HG23 1 
ATOM   1196 N N    . GLN A 1 79  ? 12.26064  -19.82152 -12.36998 1.000 10.50352  ?  160 GLN A N    1 
ATOM   1197 C CA   . GLN A 1 79  ? 13.12365  -18.76023 -12.92116 1.000 10.01863  ?  160 GLN A CA   1 
ATOM   1198 C C    . GLN A 1 79  ? 12.96976  -17.50239 -12.08977 1.000 10.27774  ?  160 GLN A C    1 
ATOM   1199 O O    . GLN A 1 79  ? 11.85439  -16.98460 -11.97764 1.000 11.02141  ?  160 GLN A O    1 
ATOM   1200 C CB   . GLN A 1 79  ? 12.69301  -18.45524 -14.35559 1.000 11.39662  ?  160 GLN A CB   1 
ATOM   1201 C CG   . GLN A 1 79  ? 12.73171  -19.68937 -15.24540 1.000 13.38659  ?  160 GLN A CG   1 
ATOM   1202 C CD   . GLN A 1 79  ? 12.47633  -19.38827 -16.68495 1.000 12.67713  ?  160 GLN A CD   1 
ATOM   1203 O OE1  . GLN A 1 79  ? 13.12128  -19.94212 -17.54424 1.000 14.04012  ?  160 GLN A OE1  1 
ATOM   1204 N NE2  . GLN A 1 79  ? 11.51898  -18.52713 -16.95397 1.000 12.74161  ?  160 GLN A NE2  1 
ATOM   1205 H H    A GLN A 1 79  ? 11.26918  -19.63886 -12.52504 0.631 12.60422  ?  160 GLN A H    1 
ATOM   1206 D D    B GLN A 1 79  ? 11.26859  -19.64106 -12.52383 0.369 12.60422  ?  160 GLN A D    1 
ATOM   1207 H HA   . GLN A 1 79  ? 14.16507  -19.08005 -12.88569 1.000 12.02235  ?  160 GLN A HA   1 
ATOM   1208 H HB2  . GLN A 1 79  ? 11.67191  -18.07393 -14.34795 1.000 13.67594  ?  160 GLN A HB2  1 
ATOM   1209 H HB3  . GLN A 1 79  ? 13.36614  -17.70988 -14.77918 1.000 13.67594  ?  160 GLN A HB3  1 
ATOM   1210 H HG2  . GLN A 1 79  ? 13.71754  -20.14816 -15.16957 1.000 16.06390  ?  160 GLN A HG2  1 
ATOM   1211 H HG3  . GLN A 1 79  ? 11.96747  -20.39036 -14.90976 1.000 16.06390  ?  160 GLN A HG3  1 
ATOM   1212 N N    . ILE A 1 80  ? 14.05396  -17.00932 -11.50623 1.000 9.11007   ?  161 ILE A N    1 
ATOM   1213 C CA   . ILE A 1 80  ? 14.00312  -15.86008 -10.61042 1.000 9.37612   ?  161 ILE A CA   1 
ATOM   1214 C C    . ILE A 1 80  ? 15.07480  -14.84422 -10.99052 1.000 9.92653   ?  161 ILE A C    1 
ATOM   1215 O O    . ILE A 1 80  ? 16.08915  -15.16151 -11.62060 1.000 9.72914   ?  161 ILE A O    1 
ATOM   1216 C CB   . ILE A 1 80  ? 14.14470  -16.24439 -9.10900  1.000 11.19101  ?  161 ILE A CB   1 
ATOM   1217 C CG1  . ILE A 1 80  ? 15.52220  -16.81345 -8.83746  1.000 11.71876  ?  161 ILE A CG1  1 
ATOM   1218 C CG2  . ILE A 1 80  ? 13.03031  -17.19360 -8.73751  1.000 16.00696  ?  161 ILE A CG2  1 
ATOM   1219 C CD1  . ILE A 1 80  ? 15.79610  -17.14104 -7.38960  1.000 17.13325  ?  161 ILE A CD1  1 
ATOM   1220 H H    A ILE A 1 80  ? 14.99231  -17.38779 -11.63525 1.000 10.93209  ?  161 ILE A H    1 
ATOM   1221 D D    B ILE A 1 80  ? 14.99165  -17.38906 -11.63636 0.000 10.93209  ?  161 ILE A D    1 
ATOM   1222 H HA   . ILE A 1 80  ? 13.03217  -15.38534 -10.75174 1.000 11.25135  ?  161 ILE A HA   1 
ATOM   1223 H HB   . ILE A 1 80  ? 14.05150  -15.35796 -8.48158  1.000 13.42921  ?  161 ILE A HB   1 
ATOM   1224 H HG12 . ILE A 1 80  ? 15.63511  -17.73459 -9.40918  1.000 14.06251  ?  161 ILE A HG12 1 
ATOM   1225 H HG13 . ILE A 1 80  ? 16.26701  -16.08380 -9.15522  1.000 14.06251  ?  161 ILE A HG13 1 
ATOM   1226 H HG21 . ILE A 1 80  ? 12.48838  -17.47531 -9.64032  1.000 19.20835  ?  161 ILE A HG21 1 
ATOM   1227 H HG22 . ILE A 1 80  ? 13.45990  -18.07966 -8.27013  1.000 19.20835  ?  161 ILE A HG22 1 
ATOM   1228 H HG23 . ILE A 1 80  ? 12.35708  -16.69494 -8.04023  1.000 19.20835  ?  161 ILE A HG23 1 
ATOM   1229 H HD11 . ILE A 1 80  ? 16.87195  -17.24077 -7.24571  1.000 20.55990  ?  161 ILE A HD11 1 
ATOM   1230 H HD12 . ILE A 1 80  ? 15.41057  -16.33564 -6.76446  1.000 20.55990  ?  161 ILE A HD12 1 
ATOM   1231 H HD13 . ILE A 1 80  ? 15.29896  -18.07774 -7.13750  1.000 20.55990  ?  161 ILE A HD13 1 
ATOM   1232 N N    . VAL A 1 81  ? 14.82642  -13.58457 -10.62061 1.000 11.03090  ?  162 VAL A N    1 
ATOM   1233 C CA   . VAL A 1 81  ? 15.81703  -12.51048 -10.71906 1.000 8.98527   ?  162 VAL A CA   1 
ATOM   1234 C C    . VAL A 1 81  ? 16.12151  -12.00125 -9.30999  1.000 10.26552  ?  162 VAL A C    1 
ATOM   1235 O O    . VAL A 1 81  ? 15.20614  -11.67057 -8.54852  1.000 12.52846  ?  162 VAL A O    1 
ATOM   1236 C CB   . VAL A 1 81  ? 15.30782  -11.34262 -11.56325 1.000 10.47016  ?  162 VAL A CB   1 
ATOM   1237 C CG1  . VAL A 1 81  ? 16.38387  -10.34666 -11.76194 1.000 10.20227  ?  162 VAL A CG1  1 
ATOM   1238 C CG2  . VAL A 1 81  ? 14.79432  -11.84552 -12.90852 1.000 12.99936  ?  162 VAL A CG2  1 
ATOM   1239 H H    A VAL A 1 81  ? 13.93153  -13.27384 -10.24243 1.000 13.23708  ?  162 VAL A H    1 
ATOM   1240 D D    B VAL A 1 81  ? 13.93057  -13.27633 -10.24266 0.000 13.23708  ?  162 VAL A D    1 
ATOM   1241 H HA   . VAL A 1 81  ? 16.72263  -12.91922 -11.16731 1.000 10.78232  ?  162 VAL A HA   1 
ATOM   1242 H HB   . VAL A 1 81  ? 14.48290  -10.85865 -11.04040 1.000 12.56419  ?  162 VAL A HB   1 
ATOM   1243 H HG11 . VAL A 1 81  ? 17.02820  -10.34021 -10.88279 1.000 12.24272  ?  162 VAL A HG11 1 
ATOM   1244 H HG12 . VAL A 1 81  ? 16.96206  -10.62021 -12.64453 1.000 12.24272  ?  162 VAL A HG12 1 
ATOM   1245 H HG13 . VAL A 1 81  ? 15.93559  -9.36296  -11.90145 1.000 12.24272  ?  162 VAL A HG13 1 
ATOM   1246 H HG21 . VAL A 1 81  ? 14.61138  -12.91789 -12.84015 1.000 15.59923  ?  162 VAL A HG21 1 
ATOM   1247 H HG22 . VAL A 1 81  ? 13.86794  -11.32518 -13.15177 1.000 15.59923  ?  162 VAL A HG22 1 
ATOM   1248 H HG23 . VAL A 1 81  ? 15.54521  -11.64453 -13.67262 1.000 15.59923  ?  162 VAL A HG23 1 
ATOM   1249 N N    . ILE A 1 82  ? 17.40392  -11.94155 -8.96362  1.000 9.37584   ?  163 ILE A N    1 
ATOM   1250 C CA   . ILE A 1 82  ? 17.90975  -11.36486 -7.72060  1.000 9.90557   ?  163 ILE A CA   1 
ATOM   1251 C C    . ILE A 1 82  ? 18.20114  -9.90455  -8.03318  1.000 10.80752  ?  163 ILE A C    1 
ATOM   1252 O O    . ILE A 1 82  ? 19.05511  -9.59347  -8.88439  1.000 10.99893  ?  163 ILE A O    1 
ATOM   1253 C CB   . ILE A 1 82  ? 19.19776  -12.09374 -7.30959  1.000 11.59425  ?  163 ILE A CB   1 
ATOM   1254 C CG1  . ILE A 1 82  ? 18.97265  -13.60938 -7.18121  1.000 18.17947  ?  163 ILE A CG1  1 
ATOM   1255 C CG2  . ILE A 1 82  ? 19.77457  -11.49922 -6.03080  1.000 16.07476  ?  163 ILE A CG2  1 
ATOM   1256 C CD1  . ILE A 1 82  ? 17.98568  -13.99734 -6.18787  1.000 21.74605  ?  163 ILE A CD1  1 
ATOM   1257 H H    A ILE A 1 82  ? 18.15485  -12.30226 -9.55217  0.890 11.25101  ?  163 ILE A H    1 
ATOM   1258 D D    B ILE A 1 82  ? 18.15397  -12.30263 -9.55307  0.110 11.25101  ?  163 ILE A D    1 
ATOM   1259 H HA   . ILE A 1 82  ? 17.18412  -11.43590 -6.91034  1.000 11.88668  ?  163 ILE A HA   1 
ATOM   1260 H HB   . ILE A 1 82  ? 19.92872  -11.94652 -8.10466  1.000 13.91310  ?  163 ILE A HB   1 
ATOM   1261 H HG12 . ILE A 1 82  ? 18.63558  -13.99179 -8.14467  1.000 21.81536  ?  163 ILE A HG12 1 
ATOM   1262 H HG13 . ILE A 1 82  ? 19.91746  -14.07712 -6.90433  1.000 21.81536  ?  163 ILE A HG13 1 
ATOM   1263 H HG21 . ILE A 1 82  ? 20.84669  -11.35130 -6.16034  1.000 19.28972  ?  163 ILE A HG21 1 
ATOM   1264 H HG22 . ILE A 1 82  ? 19.28873  -10.54373 -5.83306  1.000 19.28972  ?  163 ILE A HG22 1 
ATOM   1265 H HG23 . ILE A 1 82  ? 19.59132  -12.18723 -5.20547  1.000 19.28972  ?  163 ILE A HG23 1 
ATOM   1266 H HD11 . ILE A 1 82  ? 17.86060  -13.18249 -5.47480  1.000 26.09526  ?  163 ILE A HD11 1 
ATOM   1267 H HD12 . ILE A 1 82  ? 17.03935  -14.20149 -6.68876  1.000 26.09526  ?  163 ILE A HD12 1 
ATOM   1268 H HD13 . ILE A 1 82  ? 18.33396  -14.89230 -5.67226  1.000 26.09526  ?  163 ILE A HD13 1 
ATOM   1269 N N    . TYR A 1 83  ? 17.46220  -8.99166  -7.36578  1.000 10.06178  ?  164 TYR A N    1 
ATOM   1270 C CA   . TYR A 1 83  ? 17.51097  -7.58427  -7.74969  1.000 11.60655  ?  164 TYR A CA   1 
ATOM   1271 C C    . TYR A 1 83  ? 17.25044  -6.68873  -6.52868  1.000 11.30783  ?  164 TYR A C    1 
ATOM   1272 O O    . TYR A 1 83  ? 16.21521  -6.02769  -6.42138  1.000 11.88843  ?  164 TYR A O    1 
ATOM   1273 C CB   . TYR A 1 83  ? 16.51102  -7.31242  -8.87789  1.000 11.68405  ?  164 TYR A CB   1 
ATOM   1274 C CG   . TYR A 1 83  ? 16.52868  -5.93515  -9.45464  1.000 10.56410  ?  164 TYR A CG   1 
ATOM   1275 C CD1  . TYR A 1 83  ? 17.70815  -5.35914  -9.86573  1.000 12.26835  ?  164 TYR A CD1  1 
ATOM   1276 C CD2  . TYR A 1 83  ? 15.34983  -5.21695  -9.66481  1.000 12.47543  ?  164 TYR A CD2  1 
ATOM   1277 C CE1  . TYR A 1 83  ? 17.72472  -4.07849  -10.47167 1.000 11.92704  ?  164 TYR A CE1  1 
ATOM   1278 C CE2  . TYR A 1 83  ? 15.35420  -3.97502  -10.22749 1.000 14.51704  ?  164 TYR A CE2  1 
ATOM   1279 C CZ   . TYR A 1 83  ? 16.52052  -3.41973  -10.63174 1.000 13.09691  ?  164 TYR A CZ   1 
ATOM   1280 O OH   . TYR A 1 83  ? 16.51542  -2.16907  -11.22722 1.000 16.92831  ?  164 TYR A OH   1 
ATOM   1281 H H    A TYR A 1 83  ? 16.84465  -9.20387  -6.58220  0.990 12.07414  ?  164 TYR A H    1 
ATOM   1282 D D    B TYR A 1 83  ? 16.84519  -9.20600  -6.58235  0.010 12.07414  ?  164 TYR A D    1 
ATOM   1283 H HA   . TYR A 1 83  ? 18.52176  -7.34702  -8.08153  1.000 13.92786  ?  164 TYR A HA   1 
ATOM   1284 H HB2  . TYR A 1 83  ? 16.72153  -8.00478  -9.69302  1.000 14.02086  ?  164 TYR A HB2  1 
ATOM   1285 H HB3  . TYR A 1 83  ? 15.50675  -7.48597  -8.49132  1.000 14.02086  ?  164 TYR A HB3  1 
ATOM   1286 H HD1  . TYR A 1 83  ? 18.63693  -5.89183  -9.72431  1.000 14.72202  ?  164 TYR A HD1  1 
ATOM   1287 H HD2  . TYR A 1 83  ? 14.40788  -5.65766  -9.37343  1.000 14.97052  ?  164 TYR A HD2  1 
ATOM   1288 H HE1  . TYR A 1 83  ? 18.65126  -3.63031  -10.79884 1.000 14.31245  ?  164 TYR A HE1  1 
ATOM   1289 H HE2  . TYR A 1 83  ? 14.42733  -3.43451  -10.35060 1.000 17.42045  ?  164 TYR A HE2  1 
ATOM   1290 N N    . ASP A 1 84  ? 18.23171  -6.61692  -5.62630  1.000 10.87718  ?  165 ASP A N    1 
ATOM   1291 C CA   . ASP A 1 84  ? 18.02909  -5.82244  -4.41340  1.000 9.61699   ?  165 ASP A CA   1 
ATOM   1292 C C    . ASP A 1 84  ? 19.34267  -5.27762  -3.86073  1.000 12.35328  ?  165 ASP A C    1 
ATOM   1293 O O    . ASP A 1 84  ? 19.45334  -5.06387  -2.65285  1.000 12.04280  ?  165 ASP A O    1 
ATOM   1294 C CB   . ASP A 1 84  ? 17.28198  -6.62295  -3.36026  1.000 11.45808  ?  165 ASP A CB   1 
ATOM   1295 C CG   . ASP A 1 84  ? 16.46868  -5.71944  -2.40419  1.000 13.43343  ?  165 ASP A CG   1 
ATOM   1296 O OD1  . ASP A 1 84  ? 16.33983  -4.51656  -2.63396  1.000 13.86648  ?  165 ASP A OD1  1 
ATOM   1297 O OD2  . ASP A 1 84  ? 15.91771  -6.30723  -1.43702  1.000 14.66144  -1 165 ASP A OD2  1 
ATOM   1298 H H    A ASP A 1 84  ? 19.13880  -7.07710  -5.70255  0.855 13.05262  ?  165 ASP A H    1 
ATOM   1299 D D    B ASP A 1 84  ? 19.13910  -7.07667  -5.70156  0.145 13.05262  ?  165 ASP A D    1 
ATOM   1300 H HA   . ASP A 1 84  ? 17.41184  -4.95813  -4.65850  1.000 11.54039  ?  165 ASP A HA   1 
ATOM   1301 H HB2  . ASP A 1 84  ? 16.58937  -7.30438  -3.85427  1.000 13.74970  ?  165 ASP A HB2  1 
ATOM   1302 H HB3  . ASP A 1 84  ? 17.99961  -7.18756  -2.76502  1.000 13.74970  ?  165 ASP A HB3  1 
ATOM   1303 N N    . LEU A 1 85  ? 20.31988  -4.97099  -4.71104  1.000 10.98896  ?  166 LEU A N    1 
ATOM   1304 C CA   . LEU A 1 85  ? 21.58009  -4.45176  -4.20600  1.000 10.90250  ?  166 LEU A CA   1 
ATOM   1305 C C    . LEU A 1 85  ? 21.35657  -3.14690  -3.44491  1.000 12.98118  ?  166 LEU A C    1 
ATOM   1306 O O    . LEU A 1 85  ? 20.50112  -2.32940  -3.82763  1.000 13.16647  ?  166 LEU A O    1 
ATOM   1307 C CB   . LEU A 1 85  ? 22.55600  -4.16542  -5.34717  1.000 11.74399  ?  166 LEU A CB   1 
ATOM   1308 C CG   . LEU A 1 85  ? 23.33839  -5.32952  -5.86206  1.000 12.14569  ?  166 LEU A CG   1 
ATOM   1309 C CD1  . LEU A 1 85  ? 24.15295  -4.86571  -7.05714  1.000 17.41889  ?  166 LEU A CD1  1 
ATOM   1310 C CD2  . LEU A 1 85  ? 24.26865  -5.93664  -4.86713  1.000 15.39691  ?  166 LEU A CD2  1 
ATOM   1311 H H    A LEU A 1 85  ? 20.26866  -5.06889  -5.72504  1.000 13.18675  ?  166 LEU A H    1 
ATOM   1312 D D    B LEU A 1 85  ? 20.27056  -5.06818  -5.72520  0.000 13.18675  ?  166 LEU A D    1 
ATOM   1313 H HA   . LEU A 1 85  ? 22.01016  -5.19973  -3.53990  1.000 13.08300  ?  166 LEU A HA   1 
ATOM   1314 H HB2  . LEU A 1 85  ? 21.98657  -3.76568  -6.18626  1.000 14.09279  ?  166 LEU A HB2  1 
ATOM   1315 H HB3  . LEU A 1 85  ? 23.27559  -3.42474  -4.99836  1.000 14.09279  ?  166 LEU A HB3  1 
ATOM   1316 H HG   . LEU A 1 85  ? 22.62123  -6.10824  -6.12165  1.000 14.57482  ?  166 LEU A HG   1 
ATOM   1317 H HD11 . LEU A 1 85  ? 24.97588  -4.24332  -6.70569  1.000 20.90267  ?  166 LEU A HD11 1 
ATOM   1318 H HD12 . LEU A 1 85  ? 24.54402  -5.73835  -7.58026  1.000 20.90267  ?  166 LEU A HD12 1 
ATOM   1319 H HD13 . LEU A 1 85  ? 23.50991  -4.29035  -7.72314  1.000 20.90267  ?  166 LEU A HD13 1 
ATOM   1320 H HD21 . LEU A 1 85  ? 23.68789  -6.49502  -4.13295  1.000 18.47629  ?  166 LEU A HD21 1 
ATOM   1321 H HD22 . LEU A 1 85  ? 24.95486  -6.60635  -5.38550  1.000 18.47629  ?  166 LEU A HD22 1 
ATOM   1322 H HD23 . LEU A 1 85  ? 24.82732  -5.14198  -4.37266  1.000 18.47629  ?  166 LEU A HD23 1 
ATOM   1323 N N    . PRO A 1 86  ? 22.16313  -2.87894  -2.41617  1.000 12.15174  ?  167 PRO A N    1 
ATOM   1324 C CA   . PRO A 1 86  ? 22.12926  -1.54255  -1.80148  1.000 13.35642  ?  167 PRO A CA   1 
ATOM   1325 C C    . PRO A 1 86  ? 22.60436  -0.49962  -2.78999  1.000 13.33349  ?  167 PRO A C    1 
ATOM   1326 O O    . PRO A 1 86  ? 23.49016  -0.75367  -3.60265  1.000 13.95626  ?  167 PRO A O    1 
ATOM   1327 C CB   . PRO A 1 86  ? 23.08668  -1.66265  -0.62543  1.000 14.90504  ?  167 PRO A CB   1 
ATOM   1328 C CG   . PRO A 1 86  ? 23.54213  -3.07025  -0.55196  1.000 18.78406  ?  167 PRO A CG   1 
ATOM   1329 C CD   . PRO A 1 86  ? 23.23652  -3.72726  -1.89822  1.000 11.95620  ?  167 PRO A CD   1 
ATOM   1330 H HA   . PRO A 1 86  ? 21.13257  -1.29832  -1.43398  1.000 16.02771  ?  167 PRO A HA   1 
ATOM   1331 H HB2  . PRO A 1 86  ? 23.93574  -0.99828  -0.78609  1.000 17.88605  ?  167 PRO A HB2  1 
ATOM   1332 H HB3  . PRO A 1 86  ? 22.56470  -1.38571  0.29051   1.000 17.88605  ?  167 PRO A HB3  1 
ATOM   1333 H HG2  . PRO A 1 86  ? 24.61400  -3.09130  -0.35508  1.000 22.54087  ?  167 PRO A HG2  1 
ATOM   1334 H HG3  . PRO A 1 86  ? 23.00599  -3.58009  0.24849   1.000 22.54087  ?  167 PRO A HG3  1 
ATOM   1335 H HD2  . PRO A 1 86  ? 24.10709  -3.70386  -2.55371  1.000 14.34744  ?  167 PRO A HD2  1 
ATOM   1336 H HD3  . PRO A 1 86  ? 22.89675  -4.75450  -1.76622  1.000 14.34744  ?  167 PRO A HD3  1 
ATOM   1337 N N    . ASP A 1 87  ? 21.98725  0.69065   -2.72429  1.000 13.62523  ?  168 ASP A N    1 
ATOM   1338 C CA   . ASP A 1 87  ? 22.30231  1.75000   -3.69172  1.000 13.22553  ?  168 ASP A CA   1 
ATOM   1339 C C    . ASP A 1 87  ? 22.09770  1.21645   -5.10598  1.000 13.39901  ?  168 ASP A C    1 
ATOM   1340 O O    . ASP A 1 87  ? 22.88084  1.49517   -6.02152  1.000 13.75181  ?  168 ASP A O    1 
ATOM   1341 C CB   . ASP A 1 87  ? 23.70639  2.34473   -3.48605  1.000 14.29687  ?  168 ASP A CB   1 
ATOM   1342 C CG   . ASP A 1 87  ? 23.80251  3.30301   -2.27605  1.000 17.29917  ?  168 ASP A CG   1 
ATOM   1343 O OD1  . ASP A 1 87  ? 23.00497  3.21192   -1.32591  1.000 17.21300  ?  168 ASP A OD1  1 
ATOM   1344 O OD2  . ASP A 1 87  ? 24.67661  4.18324   -2.32342  1.000 23.98456  -1 168 ASP A OD2  1 
ATOM   1345 H H    A ASP A 1 87  ? 21.28359  0.94250   -2.03015  0.719 16.35028  ?  168 ASP A H    1 
ATOM   1346 D D    B ASP A 1 87  ? 21.28364  0.94190   -2.02988  0.281 16.35028  ?  168 ASP A D    1 
ATOM   1347 H HA   . ASP A 1 87  ? 21.61889  2.58494   -3.53711  1.000 15.87063  ?  168 ASP A HA   1 
ATOM   1348 H HB2  . ASP A 1 87  ? 24.41245  1.53053   -3.32277  1.000 17.15624  ?  168 ASP A HB2  1 
ATOM   1349 H HB3  . ASP A 1 87  ? 23.98442  2.90602   -4.37810  1.000 17.15624  ?  168 ASP A HB3  1 
ATOM   1350 N N    . ARG A 1 88  ? 21.00928  0.47652   -5.27637  1.000 14.25772  ?  169 ARG A N    1 
ATOM   1351 C CA   . ARG A 1 88  ? 20.69963  -0.15741  -6.54615  1.000 13.01389  ?  169 ARG A CA   1 
ATOM   1352 C C    . ARG A 1 88  ? 20.62248  0.88281   -7.67066  1.000 14.10813  ?  169 ARG A C    1 
ATOM   1353 O O    . ARG A 1 88  ? 20.16802  2.01859   -7.47310  1.000 15.42342  ?  169 ARG A O    1 
ATOM   1354 C CB   . ARG A 1 88  ? 19.34885  -0.86023  -6.40412  1.000 14.40986  ?  169 ARG A CB   1 
ATOM   1355 C CG   . ARG A 1 88  ? 19.23288  -2.12156  -7.23674  1.000 13.50126  ?  169 ARG A CG   1 
ATOM   1356 C CD   . ARG A 1 88  ? 17.91943  -2.81257  -7.04631  1.000 13.04283  ?  169 ARG A CD   1 
ATOM   1357 N NE   . ARG A 1 88  ? 16.81768  -2.00981  -7.50800  1.000 14.59123  ?  169 ARG A NE   1 
ATOM   1358 C CZ   . ARG A 1 88  ? 15.54714  -2.24829  -7.23397  1.000 13.77868  ?  169 ARG A CZ   1 
ATOM   1359 N NH1  . ARG A 1 88  ? 15.18143  -3.25437  -6.48079  1.000 15.12324  ?  169 ARG A NH1  1 
ATOM   1360 N NH2  . ARG A 1 88  ? 14.62139  -1.42859  -7.73370  1.000 19.86532  ?  169 ARG A NH2  1 
ATOM   1361 H H    A ARG A 1 88  ? 20.31765  0.29617   -4.54868  0.677 17.10926  ?  169 ARG A H    1 
ATOM   1362 D D    B ARG A 1 88  ? 20.31668  0.29516   -4.54986  0.323 17.10926  ?  169 ARG A D    1 
ATOM   1363 H HA   . ARG A 1 88  ? 21.47277  -0.87715  -6.81510  1.000 15.61666  ?  169 ARG A HA   1 
ATOM   1364 H HB2  . ARG A 1 88  ? 19.20392  -1.13523  -5.35939  1.000 17.29184  ?  169 ARG A HB2  1 
ATOM   1365 H HB3  . ARG A 1 88  ? 18.56181  -0.17653  -6.72229  1.000 17.29184  ?  169 ARG A HB3  1 
ATOM   1366 H HG2  . ARG A 1 88  ? 19.32939  -1.86340  -8.29132  1.000 16.20152  ?  169 ARG A HG2  1 
ATOM   1367 H HG3  . ARG A 1 88  ? 20.02404  -2.81370  -6.94845  1.000 16.20152  ?  169 ARG A HG3  1 
ATOM   1368 H HD2  . ARG A 1 88  ? 17.92010  -3.74614  -7.60893  1.000 15.65139  ?  169 ARG A HD2  1 
ATOM   1369 H HD3  . ARG A 1 88  ? 17.77156  -3.01651  -5.98582  1.000 15.65139  ?  169 ARG A HD3  1 
ATOM   1370 N N    . ASP A 1 89  ? 21.03799  0.47551   -8.86152  1.000 12.52025  ?  170 ASP A N    1 
ATOM   1371 C CA   . ASP A 1 89  ? 20.85693  1.30196   -10.05797 1.000 12.26428  ?  170 ASP A CA   1 
ATOM   1372 C C    . ASP A 1 89  ? 21.59452  2.63381   -9.91356  1.000 14.79092  ?  170 ASP A C    1 
ATOM   1373 O O    . ASP A 1 89  ? 21.03374  3.69804   -10.10572 1.000 14.48646  ?  170 ASP A O    1 
ATOM   1374 C CB   . ASP A 1 89  ? 19.36407  1.53561   -10.34787 1.000 11.44695  ?  170 ASP A CB   1 
ATOM   1375 C CG   . ASP A 1 89  ? 18.55432  0.24135   -10.35674 1.000 13.68218  ?  170 ASP A CG   1 
ATOM   1376 O OD1  . ASP A 1 89  ? 18.73248  -0.59182  -11.27490 1.000 14.10131  ?  170 ASP A OD1  1 
ATOM   1377 O OD2  . ASP A 1 89  ? 17.74255  0.08888   -9.43591  1.000 16.05735  -1 170 ASP A OD2  1 
ATOM   1378 H H    A ASP A 1 89  ? 21.50169  -0.41637  -9.03455  0.724 15.02430  ?  170 ASP A H    1 
ATOM   1379 D D    B ASP A 1 89  ? 21.50157  -0.41675  -9.03291  0.276 15.02430  ?  170 ASP A D    1 
ATOM   1380 H HA   . ASP A 1 89  ? 21.28788  0.76866   -10.90530 1.000 14.71713  ?  170 ASP A HA   1 
ATOM   1381 H HB2  . ASP A 1 89  ? 18.95038  2.18668   -9.57776  1.000 13.73635  ?  170 ASP A HB2  1 
ATOM   1382 H HB3  . ASP A 1 89  ? 19.26142  2.00406   -11.32671 1.000 13.73635  ?  170 ASP A HB3  1 
ATOM   1383 N N    . CYS A 1 90  ? 22.89829  2.54760   -9.62953  1.000 13.84093  ?  171 CYS A N    1 
ATOM   1384 C CA   A CYS A 1 90  ? 23.64140  3.72459   -9.19092  0.522 13.02668  ?  171 CYS A CA   1 
ATOM   1385 C CA   B CYS A 1 90  ? 23.64389  3.72354   -9.19033  0.478 13.02257  ?  171 CYS A CA   1 
ATOM   1386 C C    . CYS A 1 90  ? 23.68023  4.85265   -10.21726 1.000 14.68401  ?  171 CYS A C    1 
ATOM   1387 O O    . CYS A 1 90  ? 23.85245  6.00190   -9.83479  1.000 17.03955  ?  171 CYS A O    1 
ATOM   1388 C CB   A CYS A 1 90  ? 25.05956  3.32510   -8.80312  0.522 14.84727  ?  171 CYS A CB   1 
ATOM   1389 C CB   B CYS A 1 90  ? 25.06337  3.32126   -8.80529  0.478 14.84135  ?  171 CYS A CB   1 
ATOM   1390 S SG   A CYS A 1 90  ? 26.00828  2.51769   -10.14027 0.522 14.36652  ?  171 CYS A SG   1 
ATOM   1391 S SG   B CYS A 1 90  ? 26.01067  2.51574   -10.14098 0.478 14.37125  ?  171 CYS A SG   1 
ATOM   1392 H H    A CYS A 1 90  ? 23.45420  1.69473   -9.69262  0.757 16.60912  ?  171 CYS A H    1 
ATOM   1393 D D    B CYS A 1 90  ? 23.45581  1.69575   -9.69217  0.243 16.60912  ?  171 CYS A D    1 
ATOM   1394 H HA   A CYS A 1 90  ? 23.12583  4.12147   -8.31641  0.522 15.63202  ?  171 CYS A HA   1 
ATOM   1395 H HA   B CYS A 1 90  ? 23.13226  4.12070   -8.31363  0.478 15.62709  ?  171 CYS A HA   1 
ATOM   1396 H HB2  A CYS A 1 90  ? 25.60443  4.22147   -8.50692  0.522 17.81672  ?  171 CYS A HB2  1 
ATOM   1397 H HB2  B CYS A 1 90  ? 25.60930  4.21671   -8.50828  0.478 17.80962  ?  171 CYS A HB2  1 
ATOM   1398 H HB3  A CYS A 1 90  ? 25.00780  2.62711   -7.96752  0.522 17.81672  ?  171 CYS A HB3  1 
ATOM   1399 H HB3  B CYS A 1 90  ? 25.01156  2.62219   -7.97059  0.478 17.80962  ?  171 CYS A HB3  1 
ATOM   1400 N N    . ALA A 1 91  ? 23.54053  4.57014   -11.51064 1.000 14.82119  ?  172 ALA A N    1 
ATOM   1401 C CA   . ALA A 1 91  ? 23.61757  5.59193   -12.55532 1.000 15.19264  ?  172 ALA A CA   1 
ATOM   1402 C C    . ALA A 1 91  ? 22.25159  6.08358   -12.98381 1.000 19.69168  ?  172 ALA A C    1 
ATOM   1403 O O    . ALA A 1 91  ? 22.16591  6.91634   -13.88507 1.000 22.31303  ?  172 ALA A O    1 
ATOM   1404 C CB   . ALA A 1 91  ? 24.39423  5.09029   -13.77895 1.000 16.64319  ?  172 ALA A CB   1 
ATOM   1405 H H    A ALA A 1 91  ? 23.37090  3.63138   -11.87169 0.580 17.78543  ?  172 ALA A H    1 
ATOM   1406 D D    B ALA A 1 91  ? 23.37092  3.63081   -11.87023 0.420 17.78543  ?  172 ALA A D    1 
ATOM   1407 H HA   . ALA A 1 91  ? 24.17981  6.43622   -12.15638 1.000 18.23116  ?  172 ALA A HA   1 
ATOM   1408 H HB1  . ALA A 1 91  ? 23.77427  4.38007   -14.32607 1.000 19.97183  ?  172 ALA A HB1  1 
ATOM   1409 H HB2  . ALA A 1 91  ? 24.63802  5.93960   -14.41718 1.000 19.97183  ?  172 ALA A HB2  1 
ATOM   1410 H HB3  . ALA A 1 91  ? 25.30952  4.60297   -13.44300 1.000 19.97183  ?  172 ALA A HB3  1 
ATOM   1411 N N    . ALA A 1 92  ? 21.19464  5.60492   -12.37333 1.000 18.71398  ?  173 ALA A N    1 
ATOM   1412 C CA   . ALA A 1 92  ? 19.84162  5.99271   -12.76258 1.000 21.62320  ?  173 ALA A CA   1 
ATOM   1413 C C    . ALA A 1 92  ? 19.47319  7.27955   -12.04299 1.000 24.39635  ?  173 ALA A C    1 
ATOM   1414 O O    . ALA A 1 92  ? 20.01395  7.60336   -10.99259 1.000 23.25459  ?  173 ALA A O    1 
ATOM   1415 C CB   . ALA A 1 92  ? 18.84633  4.87543   -12.42301 1.000 16.51703  ?  173 ALA A CB   1 
ATOM   1416 H H    A ALA A 1 92  ? 21.23003  4.94181   -11.59910 0.831 22.45678  ?  173 ALA A H    1 
ATOM   1417 D D    B ALA A 1 92  ? 21.23071  4.94181   -11.59913 0.169 22.45678  ?  173 ALA A D    1 
ATOM   1418 H HA   . ALA A 1 92  ? 19.78208  6.16125   -13.83782 1.000 25.94784  ?  173 ALA A HA   1 
ATOM   1419 H HB1  . ALA A 1 92  ? 17.94197  5.31998   -12.00757 1.000 19.82044  ?  173 ALA A HB1  1 
ATOM   1420 H HB2  . ALA A 1 92  ? 18.60603  4.32560   -13.33298 1.000 19.82044  ?  173 ALA A HB2  1 
ATOM   1421 H HB3  . ALA A 1 92  ? 19.30042  4.20549   -11.69289 1.000 19.82044  ?  173 ALA A HB3  1 
ATOM   1422 N N    . LYS A 1 93  ? 18.51560  8.00090   -12.62782 1.000 26.01653  ?  174 LYS A N    1 
ATOM   1423 C CA   . LYS A 1 93  ? 18.02055  9.24368   -12.02572 1.000 27.05870  ?  174 LYS A CA   1 
ATOM   1424 C C    . LYS A 1 93  ? 17.15357  8.96968   -10.81354 1.000 30.45602  ?  174 LYS A C    1 
ATOM   1425 O O    . LYS A 1 93  ? 17.12725  9.78094   -9.88117  1.000 38.07452  ?  174 LYS A O    1 
ATOM   1426 C CB   . LYS A 1 93  ? 17.27346  10.06829  -13.09915 1.000 27.26848  ?  174 LYS A CB   1 
ATOM   1427 C CG   . LYS A 1 93  ? 18.22020  10.42491  -14.29233 1.000 34.68799  ?  174 LYS A CG   1 
ATOM   1428 C CD   . LYS A 1 93  ? 17.63483  11.41748  -15.29539 1.000 48.78232  ?  174 LYS A CD   1 
ATOM   1429 C CE   . LYS A 1 93  ? 17.46998  12.80468  -14.65412 1.000 91.73184  ?  174 LYS A CE   1 
ATOM   1430 N NZ   . LYS A 1 93  ? 17.01241  13.85976  -15.60702 1.000 86.78378  ?  174 LYS A NZ   1 
ATOM   1431 H H    A LYS A 1 93  ? 18.06447  7.75759   -13.50968 0.554 31.21984  ?  174 LYS A H    1 
ATOM   1432 D D    B LYS A 1 93  ? 18.06296  7.75978   -13.50950 0.446 31.21984  ?  174 LYS A D    1 
ATOM   1433 H HA   . LYS A 1 93  ? 18.85840  9.84745   -11.67707 1.000 32.47044  ?  174 LYS A HA   1 
ATOM   1434 H HB2  . LYS A 1 93  ? 16.43570  9.48699   -13.48431 1.000 32.72217  ?  174 LYS A HB2  1 
ATOM   1435 H HB3  . LYS A 1 93  ? 16.91114  10.99592  -12.65606 1.000 32.72217  ?  174 LYS A HB3  1 
ATOM   1436 H HG2  . LYS A 1 93  ? 19.13368  10.86441  -13.89173 1.000 41.62559  ?  174 LYS A HG2  1 
ATOM   1437 H HG3  . LYS A 1 93  ? 18.45414  9.50953   -14.83588 1.000 41.62559  ?  174 LYS A HG3  1 
ATOM   1438 H HD2  . LYS A 1 93  ? 18.30416  11.50871  -16.15083 1.000 58.53879  ?  174 LYS A HD2  1 
ATOM   1439 H HD3  . LYS A 1 93  ? 16.65557  11.06912  -15.62372 1.000 58.53879  ?  174 LYS A HD3  1 
ATOM   1440 H HE2  . LYS A 1 93  ? 16.73140  12.73634  -13.85542 1.000 110.07821 ?  174 LYS A HE2  1 
ATOM   1441 H HE3  . LYS A 1 93  ? 18.43097  13.11948  -14.24730 1.000 110.07821 ?  174 LYS A HE3  1 
ATOM   1442 N N    . ALA A 1 94  ? 16.47624  7.82702   -10.78673 1.000 24.07773  ?  175 ALA A N    1 
ATOM   1443 C CA   . ALA A 1 94  ? 15.69150  7.41377   -9.64150  1.000 31.10984  ?  175 ALA A CA   1 
ATOM   1444 C C    . ALA A 1 94  ? 15.91481  5.92223   -9.43093  1.000 35.51835  ?  175 ALA A C    1 
ATOM   1445 O O    . ALA A 1 94  ? 16.02303  5.17378   -10.40434 1.000 44.46474  ?  175 ALA A O    1 
ATOM   1446 C CB   . ALA A 1 94  ? 14.19057  7.63681   -9.93156  1.000 30.74181  ?  175 ALA A CB   1 
ATOM   1447 H H    A ALA A 1 94  ? 16.45493  7.15994   -11.55807 0.792 28.89328  ?  175 ALA A H    1 
ATOM   1448 D D    B ALA A 1 94  ? 16.45568  7.16069   -11.55873 0.208 28.89328  ?  175 ALA A D    1 
ATOM   1449 H HA   . ALA A 1 94  ? 15.98863  7.96296   -8.74807  1.000 37.33180  ?  175 ALA A HA   1 
ATOM   1450 H HB1  . ALA A 1 94  ? 13.88468  6.97869   -10.74483 1.000 36.89017  ?  175 ALA A HB1  1 
ATOM   1451 H HB2  . ALA A 1 94  ? 13.61766  7.40818   -9.03289  1.000 36.89017  ?  175 ALA A HB2  1 
ATOM   1452 H HB3  . ALA A 1 94  ? 14.03505  8.67726   -10.21684 1.000 36.89017  ?  175 ALA A HB3  1 
ATOM   1453 N N    . SER A 1 95  ? 15.98365  5.49015   -8.17435  1.000 39.25616  ?  176 SER A N    1 
ATOM   1454 C CA   . SER A 1 95  ? 15.98234  4.06825   -7.87454  1.000 39.46248  ?  176 SER A CA   1 
ATOM   1455 C C    . SER A 1 95  ? 14.89540  3.72879   -6.86698  1.000 30.67870  ?  176 SER A C    1 
ATOM   1456 O O    . SER A 1 95  ? 14.66916  4.47315   -5.90872  1.000 35.21176  ?  176 SER A O    1 
ATOM   1457 C CB   . SER A 1 95  ? 17.31718  3.56566   -7.30314  1.000 35.66047  ?  176 SER A CB   1 
ATOM   1458 O OG   . SER A 1 95  ? 17.25414  2.14724   -7.16535  1.000 37.38957  ?  176 SER A OG   1 
ATOM   1459 H H    A SER A 1 95  ? 16.04039  6.09697   -7.35646  0.195 47.10739  ?  176 SER A H    1 
ATOM   1460 D D    B SER A 1 95  ? 16.04035  6.09845   -7.35756  0.805 47.10739  ?  176 SER A D    1 
ATOM   1461 H HA   . SER A 1 95  ? 15.78477  3.55452   -8.81536  1.000 47.35498  ?  176 SER A HA   1 
ATOM   1462 H HB2  . SER A 1 95  ? 18.12664  3.82944   -7.98380  1.000 42.79256  ?  176 SER A HB2  1 
ATOM   1463 H HB3  . SER A 1 95  ? 17.48858  4.01877   -6.32671  1.000 42.79256  ?  176 SER A HB3  1 
ATOM   1464 N N    . ASN A 1 96  ? 14.24958  2.58529   -7.08520  1.000 31.63330  ?  177 ASN A N    1 
ATOM   1465 C CA   . ASN A 1 96  ? 13.26575  2.04553   -6.17091  1.000 31.19239  ?  177 ASN A CA   1 
ATOM   1466 C C    . ASN A 1 96  ? 13.86644  1.05983   -5.18187  1.000 33.86312  ?  177 ASN A C    1 
ATOM   1467 O O    . ASN A 1 96  ? 13.11173  0.33871   -4.51123  1.000 31.43356  ?  177 ASN A O    1 
ATOM   1468 C CB   . ASN A 1 96  ? 12.15882  1.30898   -6.94757  1.000 39.35183  ?  177 ASN A CB   1 
ATOM   1469 C CG   . ASN A 1 96  ? 11.22142  2.26027   -7.68315  1.000 60.93511  ?  177 ASN A CG   1 
ATOM   1470 O OD1  . ASN A 1 96  ? 10.26751  2.76510   -7.09006  1.000 65.29776  ?  177 ASN A OD1  1 
ATOM   1471 N ND2  . ASN A 1 96  ? 11.47388  2.48927   -8.98362  1.000 45.80867  ?  177 ASN A ND2  1 
ATOM   1472 H H    A ASN A 1 96  ? 14.39575  2.00199   -7.90909  0.839 37.95996  ?  177 ASN A H    1 
ATOM   1473 D D    B ASN A 1 96  ? 14.39685  2.00305   -7.90964  0.161 37.95996  ?  177 ASN A D    1 
ATOM   1474 H HA   . ASN A 1 96  ? 12.82659  2.88259   -5.62816  1.000 37.43087  ?  177 ASN A HA   1 
ATOM   1475 H HB2  . ASN A 1 96  ? 12.61949  0.65216   -7.68545  1.000 47.22220  ?  177 ASN A HB2  1 
ATOM   1476 H HB3  . ASN A 1 96  ? 11.56318  0.72327   -6.24738  1.000 47.22220  ?  177 ASN A HB3  1 
ATOM   1477 N N    . GLY A 1 97  ? 15.18935  0.96750   -5.10043  1.000 22.87899  ?  178 GLY A N    1 
ATOM   1478 C CA   . GLY A 1 97  ? 15.79245  -0.03059  -4.23029  1.000 17.93708  ?  178 GLY A CA   1 
ATOM   1479 C C    . GLY A 1 97  ? 15.58910  0.32883   -2.76885  1.000 19.45375  ?  178 GLY A C    1 
ATOM   1480 O O    . GLY A 1 97  ? 15.70501  1.48580   -2.37179  1.000 25.12550  ?  178 GLY A O    1 
ATOM   1481 H H    A GLY A 1 97  ? 15.85196  1.55240   -5.60960  0.614 27.45479  ?  178 GLY A H    1 
ATOM   1482 D D    B GLY A 1 97  ? 15.85392  1.55113   -5.60849  0.386 27.45479  ?  178 GLY A D    1 
ATOM   1483 H HA2  . GLY A 1 97  ? 15.33869  -1.00374  -4.41782  1.000 21.52449  ?  178 GLY A HA2  1 
ATOM   1484 H HA3  . GLY A 1 97  ? 16.86221  -0.09349  -4.42970  1.000 21.52449  ?  178 GLY A HA3  1 
ATOM   1485 N N    . GLU A 1 98  ? 15.28980  -0.68830  -1.95700  1.000 17.25119  ?  179 GLU A N    1 
ATOM   1486 C CA   . GLU A 1 98  ? 14.98551  -0.46588  -0.55396  1.000 17.27461  ?  179 GLU A CA   1 
ATOM   1487 C C    . GLU A 1 98  ? 16.20026  -0.38246  0.34553   1.000 18.33254  ?  179 GLU A C    1 
ATOM   1488 O O    . GLU A 1 98  ? 16.07135  0.08214   1.47868   1.000 18.56516  ?  179 GLU A O    1 
ATOM   1489 C CB   . GLU A 1 98  ? 14.08566  -1.59422  -0.04536  1.000 17.90019  ?  179 GLU A CB   1 
ATOM   1490 C CG   . GLU A 1 98  ? 14.73008  -2.94753  0.04589   1.000 17.34965  ?  179 GLU A CG   1 
ATOM   1491 C CD   . GLU A 1 98  ? 13.74042  -4.04389  0.33143   1.000 18.96970  ?  179 GLU A CD   1 
ATOM   1492 O OE1  . GLU A 1 98  ? 12.61974  -3.76362  0.83438   1.000 23.61085  ?  179 GLU A OE1  1 
ATOM   1493 O OE2  . GLU A 1 98  ? 14.03590  -5.21722  0.04706   1.000 14.60684  -1 179 GLU A OE2  1 
ATOM   1494 H H    A GLU A 1 98  ? 15.25182  -1.66627  -2.24426  0.607 20.70143  ?  179 GLU A H    1 
ATOM   1495 D D    B GLU A 1 98  ? 15.25156  -1.66655  -2.24328  0.393 20.70143  ?  179 GLU A D    1 
ATOM   1496 H HA   . GLU A 1 98  ? 14.46452  0.48865   -0.47960  1.000 20.72953  ?  179 GLU A HA   1 
ATOM   1497 H HB2  . GLU A 1 98  ? 13.74011  -1.33202  0.95461   1.000 21.48023  ?  179 GLU A HB2  1 
ATOM   1498 H HB3  . GLU A 1 98  ? 13.23565  -1.68526  -0.72159  1.000 21.48023  ?  179 GLU A HB3  1 
ATOM   1499 H HG2  . GLU A 1 98  ? 15.21907  -3.17298  -0.90182  1.000 20.81958  ?  179 GLU A HG2  1 
ATOM   1500 H HG3  . GLU A 1 98  ? 15.46447  -2.93791  0.85130   1.000 20.81958  ?  179 GLU A HG3  1 
ATOM   1501 N N    . PHE A 1 99  ? 17.36677  -0.82097  -0.08695  1.000 16.17314  ?  180 PHE A N    1 
ATOM   1502 C CA   . PHE A 1 99  ? 18.54535  -0.81100  0.77906   1.000 15.35540  ?  180 PHE A CA   1 
ATOM   1503 C C    . PHE A 1 99  ? 19.51908  0.27980   0.35412   1.000 14.61044  ?  180 PHE A C    1 
ATOM   1504 O O    . PHE A 1 99  ? 19.65018  0.60180   -0.83414  1.000 16.61906  ?  180 PHE A O    1 
ATOM   1505 C CB   . PHE A 1 99  ? 19.27954  -2.15238  0.74494   1.000 15.31069  ?  180 PHE A CB   1 
ATOM   1506 C CG   . PHE A 1 99  ? 18.48891  -3.29891  1.26842   1.000 14.85613  ?  180 PHE A CG   1 
ATOM   1507 C CD1  . PHE A 1 99  ? 17.70761  -3.17018  2.40549   1.000 19.43636  ?  180 PHE A CD1  1 
ATOM   1508 C CD2  . PHE A 1 99  ? 18.54228  -4.54976  0.63637   1.000 17.38896  ?  180 PHE A CD2  1 
ATOM   1509 C CE1  . PHE A 1 99  ? 16.99648  -4.24967  2.89970   1.000 16.71227  ?  180 PHE A CE1  1 
ATOM   1510 C CE2  . PHE A 1 99  ? 17.81240  -5.63014  1.12825   1.000 15.74174  ?  180 PHE A CE2  1 
ATOM   1511 C CZ   . PHE A 1 99  ? 17.04177  -5.47061  2.24483   1.000 17.00322  ?  180 PHE A CZ   1 
ATOM   1512 H H    A PHE A 1 99  ? 17.53352  -1.18793  -1.02393  0.717 19.40777  ?  180 PHE A H    1 
ATOM   1513 D D    B PHE A 1 99  ? 17.53150  -1.18760  -1.02441  0.283 19.40777  ?  180 PHE A D    1 
ATOM   1514 H HA   . PHE A 1 99  ? 18.21548  -0.61230  1.79876   1.000 18.42648  ?  180 PHE A HA   1 
ATOM   1515 H HB2  . PHE A 1 99  ? 19.54332  -2.37823  -0.28827  1.000 18.37282  ?  180 PHE A HB2  1 
ATOM   1516 H HB3  . PHE A 1 99  ? 20.18200  -2.07034  1.35069   1.000 18.37282  ?  180 PHE A HB3  1 
ATOM   1517 H HD1  . PHE A 1 99  ? 17.65303  -2.21754  2.91135   1.000 23.32363  ?  180 PHE A HD1  1 
ATOM   1518 H HD2  . PHE A 1 99  ? 19.15675  -4.67728  -0.24259  1.000 20.86675  ?  180 PHE A HD2  1 
ATOM   1519 H HE1  . PHE A 1 99  ? 16.40532  -4.14069  3.79694   1.000 20.05472  ?  180 PHE A HE1  1 
ATOM   1520 H HE2  . PHE A 1 99  ? 17.85572  -6.58733  0.62995   1.000 18.89009  ?  180 PHE A HE2  1 
ATOM   1521 H HZ   . PHE A 1 99  ? 16.46349  -6.30192  2.62020   1.000 20.40386  ?  180 PHE A HZ   1 
ATOM   1522 N N    . SER A 1 100 ? 20.20174  0.87344   1.32955   1.000 14.53454  ?  181 SER A N    1 
ATOM   1523 C CA   . SER A 1 100 ? 21.21511  1.87436   1.05276   1.000 15.70582  ?  181 SER A CA   1 
ATOM   1524 C C    . SER A 1 100 ? 22.52599  1.47633   1.72307   1.000 18.80599  ?  181 SER A C    1 
ATOM   1525 O O    . SER A 1 100 ? 22.54286  0.89139   2.80764   1.000 18.27759  ?  181 SER A O    1 
ATOM   1526 C CB   . SER A 1 100 ? 20.79168  3.28027   1.54832   1.000 21.97507  ?  181 SER A CB   1 
ATOM   1527 O OG   . SER A 1 100 ? 20.51800  3.22881   2.92346   1.000 32.53547  ?  181 SER A OG   1 
ATOM   1528 H H    A SER A 1 100 ? 20.07073  0.67764   2.32197   0.547 17.44145  ?  181 SER A H    1 
ATOM   1529 D D    B SER A 1 100 ? 20.06954  0.67651   2.32159   0.453 17.44145  ?  181 SER A D    1 
ATOM   1530 H HA   . SER A 1 100 ? 21.37630  1.92727   -0.02396  1.000 18.84699  ?  181 SER A HA   1 
ATOM   1531 H HB2  . SER A 1 100 ? 21.60259  3.98594   1.36787   1.000 26.37009  ?  181 SER A HB2  1 
ATOM   1532 H HB3  . SER A 1 100 ? 19.89612  3.59683   1.01368   1.000 26.37009  ?  181 SER A HB3  1 
ATOM   1533 N N    . ILE A 1 101 ? 23.63935  1.79673   1.06978   1.000 16.32466  ?  182 ILE A N    1 
ATOM   1534 C CA   . ILE A 1 101 ? 24.93346  1.43707   1.63120   1.000 16.64495  ?  182 ILE A CA   1 
ATOM   1535 C C    . ILE A 1 101 ? 25.09533  2.05868   3.00289   1.000 22.74220  ?  182 ILE A C    1 
ATOM   1536 O O    . ILE A 1 101 ? 25.54011  1.40923   3.94202   1.000 21.98991  ?  182 ILE A O    1 
ATOM   1537 C CB   . ILE A 1 101 ? 26.06847  1.84945   0.68008   1.000 18.37339  ?  182 ILE A CB   1 
ATOM   1538 C CG1  . ILE A 1 101 ? 26.02954  0.95424   -0.56135  1.000 18.95117  ?  182 ILE A CG1  1 
ATOM   1539 C CG2  . ILE A 1 101 ? 27.43078  1.75675   1.39468   1.000 18.74426  ?  182 ILE A CG2  1 
ATOM   1540 C CD1  . ILE A 1 101 ? 26.97812  1.35663   -1.64889  1.000 19.47165  ?  182 ILE A CD1  1 
ATOM   1541 H H    A ILE A 1 101 ? 23.67688  2.28980   0.17767   0.826 19.58959  ?  182 ILE A H    1 
ATOM   1542 D D    B ILE A 1 101 ? 23.67917  2.28969   0.17771   0.174 19.58959  ?  182 ILE A D    1 
ATOM   1543 H HA   . ILE A 1 101 ? 24.97622  0.35360   1.74237   1.000 19.97394  ?  182 ILE A HA   1 
ATOM   1544 H HB   . ILE A 1 101 ? 25.92875  2.88584   0.37272   1.000 22.04807  ?  182 ILE A HB   1 
ATOM   1545 H HG12 . ILE A 1 101 ? 26.28310  -0.06318  -0.26359  1.000 22.74140  ?  182 ILE A HG12 1 
ATOM   1546 H HG13 . ILE A 1 101 ? 25.02226  0.98096   -0.97699  1.000 22.74140  ?  182 ILE A HG13 1 
ATOM   1547 H HG21 . ILE A 1 101 ? 27.73626  2.75531   1.70719   1.000 22.49311  ?  182 ILE A HG21 1 
ATOM   1548 H HG22 . ILE A 1 101 ? 27.33133  1.10888   2.26558   1.000 22.49311  ?  182 ILE A HG22 1 
ATOM   1549 H HG23 . ILE A 1 101 ? 28.16584  1.34203   0.70490   1.000 22.49311  ?  182 ILE A HG23 1 
ATOM   1550 H HD11 . ILE A 1 101 ? 26.75879  2.38098   -1.95004  1.000 23.36597  ?  182 ILE A HD11 1 
ATOM   1551 H HD12 . ILE A 1 101 ? 27.99875  1.29045   -1.27202  1.000 23.36597  ?  182 ILE A HD12 1 
ATOM   1552 H HD13 . ILE A 1 101 ? 26.85090  0.68441   -2.49743  1.000 23.36597  ?  182 ILE A HD13 1 
ATOM   1553 N N    . ALA A 1 102 ? 24.66573  3.31241   3.14786   1.000 19.59374  ?  183 ALA A N    1 
ATOM   1554 C CA   . ALA A 1 102 ? 24.84381  4.04998   4.39423   1.000 24.35292  ?  183 ALA A CA   1 
ATOM   1555 C C    . ALA A 1 102 ? 24.03240  3.47434   5.55024   1.000 25.80529  ?  183 ALA A C    1 
ATOM   1556 O O    . ALA A 1 102 ? 24.42629  3.67141   6.70716   1.000 36.71842  ?  183 ALA A O    1 
ATOM   1557 C CB   . ALA A 1 102 ? 24.43305  5.51713   4.17872   1.000 27.90200  ?  183 ALA A CB   1 
ATOM   1558 H H    A ALA A 1 102 ? 24.19005  3.84570   2.42003   0.633 23.51249  ?  183 ALA A H    1 
ATOM   1559 D D    B ALA A 1 102 ? 24.18986  3.84781   2.42171   0.367 23.51249  ?  183 ALA A D    1 
ATOM   1560 H HA   . ALA A 1 102 ? 25.89721  3.99263   4.66836   1.000 29.22351  ?  183 ALA A HA   1 
ATOM   1561 H HB1  . ALA A 1 102 ? 24.81322  5.85409   3.21434   1.000 33.48240  ?  183 ALA A HB1  1 
ATOM   1562 H HB2  . ALA A 1 102 ? 23.34542  5.58714   4.19455   1.000 33.48240  ?  183 ALA A HB2  1 
ATOM   1563 H HB3  . ALA A 1 102 ? 24.85634  6.12525   4.97818   1.000 33.48240  ?  183 ALA A HB3  1 
ATOM   1564 N N    . ASN A 1 103 ? 22.89915  2.81368   5.31970   1.000 20.17845  ?  184 ASN A N    1 
ATOM   1565 C CA   . ASN A 1 103 ? 22.13678  2.22169   6.40485   1.000 19.98229  ?  184 ASN A CA   1 
ATOM   1566 C C    . ASN A 1 103 ? 22.26713  0.69453   6.35296   1.000 16.85458  ?  184 ASN A C    1 
ATOM   1567 O O    . ASN A 1 103 ? 21.31084  -0.03603  6.06293   1.000 20.89109  ?  184 ASN A O    1 
ATOM   1568 C CB   . ASN A 1 103 ? 20.64944  2.71083   6.35527   1.000 25.32235  ?  184 ASN A CB   1 
ATOM   1569 C CG   . ASN A 1 103 ? 19.75513  1.96013   7.36558   1.000 63.89160  ?  184 ASN A CG   1 
ATOM   1570 O OD1  . ASN A 1 103 ? 20.24401  1.18933   8.20863   1.000 43.01784  ?  184 ASN A OD1  1 
ATOM   1571 N ND2  . ASN A 1 103 ? 18.43411  2.17987   7.28406   1.000 51.99199  ?  184 ASN A ND2  1 
ATOM   1572 H H    . ASN A 1 103 ? 22.49121  2.67598   4.39503   0.354 24.21414  ?  184 ASN A H    1 
ATOM   1573 H HA   . ASN A 1 103 ? 22.55613  2.54707   7.35688   1.000 23.97875  ?  184 ASN A HA   1 
ATOM   1574 H HB2  . ASN A 1 103 ? 20.61424  3.77367   6.59450   1.000 30.38682  ?  184 ASN A HB2  1 
ATOM   1575 H HB3  . ASN A 1 103 ? 20.24992  2.54030   5.35557   1.000 30.38682  ?  184 ASN A HB3  1 
ATOM   1576 N N    . ASN A 1 104 ? 23.46585  0.19486   6.66509   1.000 21.03072  ?  185 ASN A N    1 
ATOM   1577 C CA   . ASN A 1 104 ? 23.71638  -1.23126  6.84936   1.000 21.34869  ?  185 ASN A CA   1 
ATOM   1578 C C    . ASN A 1 104 ? 23.37789  -2.02725  5.59203   1.000 20.22027  ?  185 ASN A C    1 
ATOM   1579 O O    . ASN A 1 104 ? 22.86699  -3.16678  5.66821   1.000 18.81939  ?  185 ASN A O    1 
ATOM   1580 C CB   . ASN A 1 104 ? 22.88961  -1.83611  7.98103   1.000 24.74888  ?  185 ASN A CB   1 
ATOM   1581 C CG   . ASN A 1 104 ? 23.33346  -1.37803  9.30248   1.000 49.31940  ?  185 ASN A CG   1 
ATOM   1582 O OD1  . ASN A 1 104 ? 24.41081  -1.75546  9.76679   1.000 47.85608  ?  185 ASN A OD1  1 
ATOM   1583 N ND2  . ASN A 1 104 ? 22.50368  -0.54947  9.94970   1.000 42.76235  ?  185 ASN A ND2  1 
ATOM   1584 H H    A ASN A 1 104 ? 24.29880  0.76813   6.79908   0.606 25.23686  ?  185 ASN A H    1 
ATOM   1585 D D    B ASN A 1 104 ? 24.29809  0.76922   6.79882   0.394 25.23686  ?  185 ASN A D    1 
ATOM   1586 H HA   . ASN A 1 104 ? 24.77658  -1.31808  7.08715   1.000 25.61843  ?  185 ASN A HA   1 
ATOM   1587 H HB2  . ASN A 1 104 ? 21.84625  -1.54703  7.85482   1.000 29.69865  ?  185 ASN A HB2  1 
ATOM   1588 H HB3  . ASN A 1 104 ? 22.98205  -2.92174  7.94986   1.000 29.69865  ?  185 ASN A HB3  1 
ATOM   1589 N N    . GLY A 1 105 ? 23.63722  -1.43661  4.42666   1.000 15.99051  ?  186 GLY A N    1 
ATOM   1590 C CA   . GLY A 1 105 ? 23.10162  -2.00771  3.20289   1.000 19.31363  ?  186 GLY A CA   1 
ATOM   1591 C C    . GLY A 1 105 ? 23.62350  -3.40648  2.93215   1.000 14.69617  ?  186 GLY A C    1 
ATOM   1592 O O    . GLY A 1 105 ? 22.85930  -4.31121  2.58174   1.000 14.59210  ?  186 GLY A O    1 
ATOM   1593 H H    A GLY A 1 105 ? 24.19532  -0.59173  4.30379   0.505 19.18861  ?  186 GLY A H    1 
ATOM   1594 D D    B GLY A 1 105 ? 24.19482  -0.59188  4.30055   0.495 19.18861  ?  186 GLY A D    1 
ATOM   1595 H HA2  . GLY A 1 105 ? 22.01503  -2.05597  3.27432   1.000 23.17636  ?  186 GLY A HA2  1 
ATOM   1596 H HA3  . GLY A 1 105 ? 23.37399  -1.37204  2.36037   1.000 23.17636  ?  186 GLY A HA3  1 
ATOM   1597 N N    . GLN A 1 106 ? 24.93398  -3.60052  3.07753   1.000 14.09021  ?  187 GLN A N    1 
ATOM   1598 C CA   . GLN A 1 106 ? 25.49372  -4.90787  2.78037   1.000 14.20071  ?  187 GLN A CA   1 
ATOM   1599 C C    . GLN A 1 106 ? 24.93605  -5.96912  3.71325   1.000 13.04215  ?  187 GLN A C    1 
ATOM   1600 O O    . GLN A 1 106 ? 24.60687  -7.07305  3.29128   1.000 15.42662  ?  187 GLN A O    1 
ATOM   1601 C CB   . GLN A 1 106 ? 27.00653  -4.85544  2.86424   1.000 17.10813  ?  187 GLN A CB   1 
ATOM   1602 C CG   . GLN A 1 106 ? 27.64784  -6.16551  2.47344   1.000 18.09625  ?  187 GLN A CG   1 
ATOM   1603 C CD   . GLN A 1 106 ? 29.13588  -6.06860  2.33491   1.000 21.48936  ?  187 GLN A CD   1 
ATOM   1604 O OE1  . GLN A 1 106 ? 29.68706  -5.03609  1.95768   1.000 19.88985  ?  187 GLN A OE1  1 
ATOM   1605 N NE2  . GLN A 1 106 ? 29.81101  -7.15030  2.69615   1.000 23.21721  ?  187 GLN A NE2  1 
ATOM   1606 H H    A GLN A 1 106 ? 25.60506  -2.89761  3.38735   0.759 16.90825  ?  187 GLN A H    1 
ATOM   1607 D D    B GLN A 1 106 ? 25.60676  -2.89916  3.38716   0.241 16.90825  ?  187 GLN A D    1 
ATOM   1608 H HA   . GLN A 1 106 ? 25.22229  -5.18295  1.76118   1.000 17.04085  ?  187 GLN A HA   1 
ATOM   1609 H HB2  . GLN A 1 106 ? 27.37458  -4.08245  2.18961   1.000 20.52976  ?  187 GLN A HB2  1 
ATOM   1610 H HB3  . GLN A 1 106 ? 27.29922  -4.62624  3.88888   1.000 20.52976  ?  187 GLN A HB3  1 
ATOM   1611 H HG2  . GLN A 1 106 ? 27.42928  -6.90952  3.23946   1.000 21.71550  ?  187 GLN A HG2  1 
ATOM   1612 H HG3  . GLN A 1 106 ? 27.24119  -6.48707  1.51462   1.000 21.71550  ?  187 GLN A HG3  1 
ATOM   1613 N N    . ALA A 1 107 ? 24.85328  -5.65993  5.02150   1.000 13.92140  ?  188 ALA A N    1 
ATOM   1614 C CA   . ALA A 1 107 ? 24.34023  -6.63591  5.96468   1.000 14.10618  ?  188 ALA A CA   1 
ATOM   1615 C C    . ALA A 1 107 ? 22.89211  -6.97999  5.64770   1.000 13.63493  ?  188 ALA A C    1 
ATOM   1616 O O    . ALA A 1 107 ? 22.48166  -8.13748  5.74097   1.000 14.67779  ?  188 ALA A O    1 
ATOM   1617 C CB   . ALA A 1 107 ? 24.42682  -6.09668  7.39575   1.000 17.32935  ?  188 ALA A CB   1 
ATOM   1618 H H    A ALA A 1 107 ? 25.12789  -4.76778  5.43265   0.711 16.70568  ?  188 ALA A H    1 
ATOM   1619 D D    B ALA A 1 107 ? 25.12719  -4.76867  5.43505   0.289 16.70568  ?  188 ALA A D    1 
ATOM   1620 H HA   . ALA A 1 107 ? 24.95222  -7.53524  5.89558   1.000 16.92742  ?  188 ALA A HA   1 
ATOM   1621 H HB1  . ALA A 1 107 ? 24.19220  -5.03225  7.38870   1.000 20.79522  ?  188 ALA A HB1  1 
ATOM   1622 H HB2  . ALA A 1 107 ? 23.71083  -6.63098  8.02024   1.000 20.79522  ?  188 ALA A HB2  1 
ATOM   1623 H HB3  . ALA A 1 107 ? 25.43760  -6.25202  7.77296   1.000 20.79522  ?  188 ALA A HB3  1 
ATOM   1624 N N    . ASN A 1 108 ? 22.09399  -5.97839  5.25481   1.000 13.76044  ?  189 ASN A N    1 
ATOM   1625 C CA   . ASN A 1 108 ? 20.70751  -6.25058  4.91269   1.000 13.59868  ?  189 ASN A CA   1 
ATOM   1626 C C    . ASN A 1 108 ? 20.62961  -7.11219  3.65191   1.000 14.37384  ?  189 ASN A C    1 
ATOM   1627 O O    . ASN A 1 108 ? 19.79390  -8.01018  3.55150   1.000 13.48927  ?  189 ASN A O    1 
ATOM   1628 C CB   . ASN A 1 108 ? 19.95043  -4.95024  4.67978   1.000 16.84511  ?  189 ASN A CB   1 
ATOM   1629 C CG   . ASN A 1 108 ? 19.70373  -4.15920  5.98001   1.000 20.23311  ?  189 ASN A CG   1 
ATOM   1630 O OD1  . ASN A 1 108 ? 19.52273  -4.74348  7.02782   1.000 26.74539  ?  189 ASN A OD1  1 
ATOM   1631 N ND2  . ASN A 1 108 ? 19.73000  -2.84447  5.88595   1.000 25.08356  ?  189 ASN A ND2  1 
ATOM   1632 H H    A ASN A 1 108 ? 22.37542  -5.00180  5.16839   0.596 16.51253  ?  189 ASN A H    1 
ATOM   1633 D D    B ASN A 1 108 ? 22.37298  -5.00117  5.16760   0.404 16.51253  ?  189 ASN A D    1 
ATOM   1634 H HA   . ASN A 1 108 ? 20.23995  -6.77544  5.74576   1.000 16.31841  ?  189 ASN A HA   1 
ATOM   1635 H HB2  . ASN A 1 108 ? 20.52946  -4.31843  4.00626   1.000 20.21414  ?  189 ASN A HB2  1 
ATOM   1636 H HB3  . ASN A 1 108 ? 18.98146  -5.17859  4.23586   1.000 20.21414  ?  189 ASN A HB3  1 
ATOM   1637 N N    . TYR A 1 109 ? 21.53554  -6.87175  2.68790   1.000 12.94904  ?  190 TYR A N    1 
ATOM   1638 C CA   . TYR A 1 109 ? 21.57075  -7.68562  1.46807   1.000 11.38411  ?  190 TYR A CA   1 
ATOM   1639 C C    . TYR A 1 109 ? 21.94748  -9.11580  1.79579   1.000 12.28305  ?  190 TYR A C    1 
ATOM   1640 O O    . TYR A 1 109 ? 21.37457  -10.07463 1.26011   1.000 11.86467  ?  190 TYR A O    1 
ATOM   1641 C CB   . TYR A 1 109 ? 22.54005  -7.09037  0.47088   1.000 12.58752  ?  190 TYR A CB   1 
ATOM   1642 C CG   . TYR A 1 109 ? 22.48119  -7.77648  -0.86130  1.000 10.26157  ?  190 TYR A CG   1 
ATOM   1643 C CD1  . TYR A 1 109 ? 21.51740  -7.40524  -1.79598  1.000 11.45908  ?  190 TYR A CD1  1 
ATOM   1644 C CD2  . TYR A 1 109 ? 23.34883  -8.77839  -1.19694  1.000 10.90421  ?  190 TYR A CD2  1 
ATOM   1645 C CE1  . TYR A 1 109 ? 21.41173  -8.05368  -3.01339  1.000 11.54605  ?  190 TYR A CE1  1 
ATOM   1646 C CE2  . TYR A 1 109 ? 23.26437  -9.39729  -2.45754  1.000 11.81631  ?  190 TYR A CE2  1 
ATOM   1647 C CZ   . TYR A 1 109 ? 22.30317  -9.01613  -3.33142  1.000 10.59490  ?  190 TYR A CZ   1 
ATOM   1648 O OH   . TYR A 1 109 ? 22.21980  -9.65325  -4.57327  1.000 12.28127  ?  190 TYR A OH   1 
ATOM   1649 H H    A TYR A 1 109 ? 22.24162  -6.13650  2.72342   0.625 15.53884  ?  190 TYR A H    1 
ATOM   1650 D D    B TYR A 1 109 ? 22.24254  -6.13727  2.72100   0.375 15.53884  ?  190 TYR A D    1 
ATOM   1651 H HA   . TYR A 1 109 ? 20.58325  -7.68586  1.00661   1.000 13.66093  ?  190 TYR A HA   1 
ATOM   1652 H HB2  . TYR A 1 109 ? 22.29699  -6.03833  0.32183   1.000 15.10502  ?  190 TYR A HB2  1 
ATOM   1653 H HB3  . TYR A 1 109 ? 23.55433  -7.18743  0.85808   1.000 15.10502  ?  190 TYR A HB3  1 
ATOM   1654 H HD1  . TYR A 1 109 ? 20.84004  -6.59613  -1.56595  1.000 13.75089  ?  190 TYR A HD1  1 
ATOM   1655 H HD2  . TYR A 1 109 ? 24.10224  -9.09607  -0.49136  1.000 13.08505  ?  190 TYR A HD2  1 
ATOM   1656 H HE1  . TYR A 1 109 ? 20.62300  -7.79219  -3.70326  1.000 13.85526  ?  190 TYR A HE1  1 
ATOM   1657 H HE2  . TYR A 1 109 ? 23.96432  -10.17426 -2.72735  1.000 14.17957  ?  190 TYR A HE2  1 
ATOM   1658 N N    . GLU A 1 110 ? 22.95048  -9.30740  2.67180   1.000 13.15137  ?  191 GLU A N    1 
ATOM   1659 C CA   . GLU A 1 110 ? 23.34876  -10.66467 3.01221   1.000 13.14669  ?  191 GLU A CA   1 
ATOM   1660 C C    . GLU A 1 110 ? 22.21235  -11.39753 3.70037   1.000 12.19622  ?  191 GLU A C    1 
ATOM   1661 O O    . GLU A 1 110 ? 21.97535  -12.57241 3.42856   1.000 13.80272  ?  191 GLU A O    1 
ATOM   1662 C CB   . GLU A 1 110 ? 24.58611  -10.60553 3.89675   1.000 16.51673  ?  191 GLU A CB   1 
ATOM   1663 C CG   . GLU A 1 110 ? 25.81695  -10.10014 3.10687   1.000 18.26502  ?  191 GLU A CG   1 
ATOM   1664 C CD   . GLU A 1 110 ? 27.06240  -9.92975  3.95813   1.000 25.06466  ?  191 GLU A CD   1 
ATOM   1665 O OE1  . GLU A 1 110 ? 26.97300  -10.17489 5.16653   1.000 28.97301  ?  191 GLU A OE1  1 
ATOM   1666 O OE2  . GLU A 1 110 ? 28.09568  -9.52242  3.38537   1.000 30.89653  -1 191 GLU A OE2  1 
ATOM   1667 H H    A GLU A 1 110 ? 23.47776  -8.56864  3.13721   0.982 15.78165  ?  191 GLU A H    1 
ATOM   1668 D D    B GLU A 1 110 ? 23.47919  -8.57045  3.13845   0.018 15.78165  ?  191 GLU A D    1 
ATOM   1669 H HA   . GLU A 1 110 ? 23.60139  -11.22316 2.11089   1.000 15.77603  ?  191 GLU A HA   1 
ATOM   1670 H HB2  . GLU A 1 110 ? 24.40468  -9.92219  4.72634   1.000 19.82008  ?  191 GLU A HB2  1 
ATOM   1671 H HB3  . GLU A 1 110 ? 24.80638  -11.60310 4.27680   1.000 19.82008  ?  191 GLU A HB3  1 
ATOM   1672 H HG2  . GLU A 1 110 ? 26.04799  -10.81829 2.32011   1.000 21.91802  ?  191 GLU A HG2  1 
ATOM   1673 H HG3  . GLU A 1 110 ? 25.57885  -9.13090  2.66872   1.000 21.91802  ?  191 GLU A HG3  1 
ATOM   1674 N N    . ASN A 1 111 ? 21.41879  -10.68540 4.52140   1.000 12.63426  ?  192 ASN A N    1 
ATOM   1675 C CA   . ASN A 1 111 ? 20.25958  -11.31026 5.13359   1.000 12.59167  ?  192 ASN A CA   1 
ATOM   1676 C C    . ASN A 1 111 ? 19.19336  -11.66555 4.07837   1.000 14.60871  ?  192 ASN A C    1 
ATOM   1677 O O    . ASN A 1 111 ? 18.55688  -12.72706 4.16325   1.000 15.17725  ?  192 ASN A O    1 
ATOM   1678 C CB   . ASN A 1 111 ? 19.69174  -10.38163 6.20057   1.000 15.69233  ?  192 ASN A CB   1 
ATOM   1679 C CG   . ASN A 1 111 ? 18.38691  -10.89286 6.75665   1.000 27.67148  ?  192 ASN A CG   1 
ATOM   1680 O OD1  . ASN A 1 111 ? 17.31151  -10.32872 6.51511   1.000 29.26510  ?  192 ASN A OD1  1 
ATOM   1681 N ND2  . ASN A 1 111 ? 18.46983  -12.02186 7.46188   1.000 30.48488  ?  192 ASN A ND2  1 
ATOM   1682 H H    A ASN A 1 111 ? 21.55773  -9.70526  4.76723   0.845 15.16111  ?  192 ASN A H    1 
ATOM   1683 D D    B ASN A 1 111 ? 21.55557  -9.70534  4.76875   0.155 15.16111  ?  192 ASN A D    1 
ATOM   1684 H HA   . ASN A 1 111 ? 20.55963  -12.23972 5.61749   1.000 15.11000  ?  192 ASN A HA   1 
ATOM   1685 H HB2  . ASN A 1 111 ? 20.40394  -10.30105 7.02178   1.000 18.83080  ?  192 ASN A HB2  1 
ATOM   1686 H HB3  . ASN A 1 111 ? 19.51424  -9.39909  5.76329   1.000 18.83080  ?  192 ASN A HB3  1 
ATOM   1687 N N    . TYR A 1 112 ? 18.99228  -10.79005 3.06851   1.000 11.88270  ?  193 TYR A N    1 
ATOM   1688 C CA   . TYR A 1 112 ? 18.10449  -11.09703 1.94309   1.000 11.90100  ?  193 TYR A CA   1 
ATOM   1689 C C    . TYR A 1 112 ? 18.53700  -12.37925 1.23198   1.000 11.85921  ?  193 TYR A C    1 
ATOM   1690 O O    . TYR A 1 112 ? 17.72178  -13.25740 0.98862   1.000 11.75609  ?  193 TYR A O    1 
ATOM   1691 C CB   . TYR A 1 112 ? 18.06970  -9.86760  1.04753   1.000 12.53435  ?  193 TYR A CB   1 
ATOM   1692 C CG   . TYR A 1 112 ? 17.66846  -10.02278 -0.42266  1.000 12.27627  ?  193 TYR A CG   1 
ATOM   1693 C CD1  . TYR A 1 112 ? 16.34294  -9.97823  -0.82287  1.000 12.70606  ?  193 TYR A CD1  1 
ATOM   1694 C CD2  . TYR A 1 112 ? 18.63450  -10.13500 -1.40458  1.000 11.92632  ?  193 TYR A CD2  1 
ATOM   1695 C CE1  . TYR A 1 112 ? 16.00342  -10.04493 -2.18232  1.000 10.58834  ?  193 TYR A CE1  1 
ATOM   1696 C CE2  . TYR A 1 112 ? 18.30799  -10.22940 -2.71848  1.000 12.65566  ?  193 TYR A CE2  1 
ATOM   1697 C CZ   . TYR A 1 112 ? 16.98386  -10.17731 -3.10036  1.000 12.56902  ?  193 TYR A CZ   1 
ATOM   1698 O OH   . TYR A 1 112 ? 16.69203  -10.25935 -4.44260  1.000 13.32474  ?  193 TYR A OH   1 
ATOM   1699 H H    A TYR A 1 112 ? 19.42918  -9.87032  3.00831   0.887 14.25924  ?  193 TYR A H    1 
ATOM   1700 D D    B TYR A 1 112 ? 19.42803  -9.86992  3.00620   0.113 14.25924  ?  193 TYR A D    1 
ATOM   1701 H HA   . TYR A 1 112 ? 17.08407  -11.29547 2.27091   1.000 14.28120  ?  193 TYR A HA   1 
ATOM   1702 H HB2  . TYR A 1 112 ? 17.36064  -9.16508  1.48548   1.000 15.04122  ?  193 TYR A HB2  1 
ATOM   1703 H HB3  . TYR A 1 112 ? 19.07053  -9.43581  1.04741   1.000 15.04122  ?  193 TYR A HB3  1 
ATOM   1704 H HD1  . TYR A 1 112 ? 15.56312  -9.89127  -0.08077  1.000 15.24727  ?  193 TYR A HD1  1 
ATOM   1705 H HD2  . TYR A 1 112 ? 19.67598  -10.14790 -1.11900  1.000 14.31159  ?  193 TYR A HD2  1 
ATOM   1706 H HE1  . TYR A 1 112 ? 14.96978  -9.99100  -2.49066  1.000 12.70601  ?  193 TYR A HE1  1 
ATOM   1707 H HE2  . TYR A 1 112 ? 19.08238  -10.34490 -3.46237  1.000 15.18680  ?  193 TYR A HE2  1 
ATOM   1708 N N    . ILE A 1 113 ? 19.83024  -12.53922 0.94255   1.000 10.38426  ?  194 ILE A N    1 
ATOM   1709 C CA   . ILE A 1 113 ? 20.30475  -13.76060 0.30153   1.000 11.79709  ?  194 ILE A CA   1 
ATOM   1710 C C    . ILE A 1 113 ? 20.08764  -14.96575 1.21679   1.000 11.76067  ?  194 ILE A C    1 
ATOM   1711 O O    . ILE A 1 113 ? 19.68311  -16.03577 0.77760   1.000 11.99901  ?  194 ILE A O    1 
ATOM   1712 C CB   . ILE A 1 113 ? 21.78855  -13.60182 -0.12121  1.000 10.36725  ?  194 ILE A CB   1 
ATOM   1713 C CG1  . ILE A 1 113 ? 21.96527  -12.57140 -1.23664  1.000 9.79486   ?  194 ILE A CG1  1 
ATOM   1714 C CG2  . ILE A 1 113 ? 22.39786  -14.93630 -0.51260  1.000 11.16200  ?  194 ILE A CG2  1 
ATOM   1715 C CD1  . ILE A 1 113 ? 21.23396  -12.85976 -2.49389  1.000 12.16794  ?  194 ILE A CD1  1 
ATOM   1716 H H    A ILE A 1 113 ? 20.55965  -11.85308 1.13643   1.000 12.46111  ?  194 ILE A H    1 
ATOM   1717 D D    B ILE A 1 113 ? 20.56125  -11.85452 1.13550   0.000 12.46111  ?  194 ILE A D    1 
ATOM   1718 H HA   . ILE A 1 113 ? 19.72125  -13.93133 -0.60317  1.000 14.15651  ?  194 ILE A HA   1 
ATOM   1719 H HB   . ILE A 1 113 ? 22.32166  -13.22595 0.75207   1.000 12.44070  ?  194 ILE A HB   1 
ATOM   1720 H HG12 . ILE A 1 113 ? 21.61370  -11.60663 -0.87098  1.000 11.75384  ?  194 ILE A HG12 1 
ATOM   1721 H HG13 . ILE A 1 113 ? 23.02515  -12.51253 -1.48422  1.000 11.75384  ?  194 ILE A HG13 1 
ATOM   1722 H HG21 . ILE A 1 113 ? 22.41333  -15.01415 -1.59970  1.000 13.39440  ?  194 ILE A HG21 1 
ATOM   1723 H HG22 . ILE A 1 113 ? 23.41383  -14.99086 -0.12155  1.000 13.39440  ?  194 ILE A HG22 1 
ATOM   1724 H HG23 . ILE A 1 113 ? 21.79365  -15.73958 -0.09098  1.000 13.39440  ?  194 ILE A HG23 1 
ATOM   1725 H HD11 . ILE A 1 113 ? 21.51905  -13.84925 -2.85130  1.000 14.60153  ?  194 ILE A HD11 1 
ATOM   1726 H HD12 . ILE A 1 113 ? 20.16250  -12.83053 -2.29588  1.000 14.60153  ?  194 ILE A HD12 1 
ATOM   1727 H HD13 . ILE A 1 113 ? 21.49527  -12.10654 -3.23718  1.000 14.60153  ?  194 ILE A HD13 1 
ATOM   1728 N N    . ASP A 1 114 ? 20.35436  -14.80291 2.50941   1.000 12.66497  ?  195 ASP A N    1 
ATOM   1729 C CA   . ASP A 1 114 ? 20.23308  -15.94136 3.42807   1.000 11.83774  ?  195 ASP A CA   1 
ATOM   1730 C C    . ASP A 1 114 ? 18.80392  -16.45188 3.46324   1.000 11.73444  ?  195 ASP A C    1 
ATOM   1731 O O    . ASP A 1 114 ? 18.56154  -17.66564 3.52767   1.000 14.34966  ?  195 ASP A O    1 
ATOM   1732 C CB   . ASP A 1 114 ? 20.66095  -15.55019 4.84516   1.000 11.31313  ?  195 ASP A CB   1 
ATOM   1733 C CG   . ASP A 1 114 ? 22.15518  -15.35879 4.99590   1.000 16.43101  ?  195 ASP A CG   1 
ATOM   1734 O OD1  . ASP A 1 114 ? 22.94548  -15.73692 4.11379   1.000 15.95656  ?  195 ASP A OD1  1 
ATOM   1735 O OD2  . ASP A 1 114 ? 22.53385  -14.77171 6.05323   1.000 20.47068  -1 195 ASP A OD2  1 
ATOM   1736 H H    A ASP A 1 114 ? 20.64733  -13.92771 2.94369   0.996 15.19796  ?  195 ASP A H    1 
ATOM   1737 D D    B ASP A 1 114 ? 20.64744  -13.92892 2.94604   0.004 15.19796  ?  195 ASP A D    1 
ATOM   1738 H HA   . ASP A 1 114 ? 20.89729  -16.73106 3.07696   1.000 14.20529  ?  195 ASP A HA   1 
ATOM   1739 H HB2  . ASP A 1 114 ? 20.17629  -14.61108 5.11213   1.000 13.57576  ?  195 ASP A HB2  1 
ATOM   1740 H HB3  . ASP A 1 114 ? 20.35474  -16.33693 5.53464   1.000 13.57576  ?  195 ASP A HB3  1 
ATOM   1741 N N    . GLN A 1 115 ? 17.83895  -15.54130 3.42003   1.000 12.50000  ?  196 GLN A N    1 
ATOM   1742 C CA   . GLN A 1 115 ? 16.43297  -15.94206 3.42508   1.000 13.25561  ?  196 GLN A CA   1 
ATOM   1743 C C    . GLN A 1 115 ? 16.01693  -16.62551 2.14281   1.000 14.29731  ?  196 GLN A C    1 
ATOM   1744 O O    . GLN A 1 115 ? 15.19192  -17.53044 2.16255   1.000 15.33824  ?  196 GLN A O    1 
ATOM   1745 C CB   . GLN A 1 115 ? 15.54241  -14.71568 3.62878   1.000 17.23798  ?  196 GLN A CB   1 
ATOM   1746 C CG   . GLN A 1 115 ? 15.60631  -14.10590 5.05398   1.000 18.10625  ?  196 GLN A CG   1 
ATOM   1747 C CD   . GLN A 1 115 ? 14.57250  -13.00409 5.20235   1.000 38.84841  ?  196 GLN A CD   1 
ATOM   1748 O OE1  . GLN A 1 115 ? 13.37435  -13.22901 5.02293   1.000 46.76632  ?  196 GLN A OE1  1 
ATOM   1749 N NE2  . GLN A 1 115 ? 15.03493  -11.79884 5.49078   1.000 34.60183  ?  196 GLN A NE2  1 
ATOM   1750 H H    A GLN A 1 115 ? 17.99035  -14.53334 3.38151   0.952 15.00000  ?  196 GLN A H    1 
ATOM   1751 D D    B GLN A 1 115 ? 17.98770  -14.53295 3.38148   0.048 15.00000  ?  196 GLN A D    1 
ATOM   1752 H HA   . GLN A 1 115 ? 16.30167  -16.64315 4.24930   1.000 15.90673  ?  196 GLN A HA   1 
ATOM   1753 H HB2  . GLN A 1 115 ? 15.85017  -13.94210 2.92524   1.000 20.68557  ?  196 GLN A HB2  1 
ATOM   1754 H HB3  . GLN A 1 115 ? 14.50798  -15.00208 3.43894   1.000 20.68557  ?  196 GLN A HB3  1 
ATOM   1755 H HG2  . GLN A 1 115 ? 15.39913  -14.88016 5.79269   1.000 21.72750  ?  196 GLN A HG2  1 
ATOM   1756 H HG3  . GLN A 1 115 ? 16.59539  -13.68144 5.22617   1.000 21.72750  ?  196 GLN A HG3  1 
ATOM   1757 N N    . ILE A 1 116 ? 16.57671  -16.19830 1.00843   1.000 13.09624  ?  197 ILE A N    1 
ATOM   1758 C CA   . ILE A 1 116 ? 16.33919  -16.89200 -0.26351  1.000 12.92766  ?  197 ILE A CA   1 
ATOM   1759 C C    . ILE A 1 116 ? 16.92726  -18.29911 -0.20776  1.000 11.83547  ?  197 ILE A C    1 
ATOM   1760 O O    . ILE A 1 116 ? 16.27888  -19.25906 -0.59945  1.000 13.43836  ?  197 ILE A O    1 
ATOM   1761 C CB   . ILE A 1 116 ? 16.91358  -16.06843 -1.44154  1.000 12.40109  ?  197 ILE A CB   1 
ATOM   1762 C CG1  . ILE A 1 116 ? 16.05444  -14.81203 -1.61965  1.000 12.22166  ?  197 ILE A CG1  1 
ATOM   1763 C CG2  . ILE A 1 116 ? 16.96520  -16.90018 -2.69697  1.000 12.95361  ?  197 ILE A CG2  1 
ATOM   1764 C CD1  . ILE A 1 116 ? 16.65629  -13.82456 -2.51987  1.000 16.45896  ?  197 ILE A CD1  1 
ATOM   1765 H H    A ILE A 1 116 ? 17.19095  -15.38734 0.93448   0.916 15.71549  ?  197 ILE A H    1 
ATOM   1766 D D    B ILE A 1 116 ? 17.19115  -15.38769 0.93235   0.084 15.71549  ?  197 ILE A D    1 
ATOM   1767 H HA   . ILE A 1 116 ? 15.26479  -16.98501 -0.42200  1.000 15.51319  ?  197 ILE A HA   1 
ATOM   1768 H HB   . ILE A 1 116 ? 17.93811  -15.76724 -1.22308  1.000 14.88131  ?  197 ILE A HB   1 
ATOM   1769 H HG12 . ILE A 1 116 ? 15.08908  -15.10058 -2.03548  1.000 14.66599  ?  197 ILE A HG12 1 
ATOM   1770 H HG13 . ILE A 1 116 ? 15.91525  -14.33888 -0.64761  1.000 14.66599  ?  197 ILE A HG13 1 
ATOM   1771 H HG21 . ILE A 1 116 ? 17.66510  -17.72263 -2.54924  1.000 15.54433  ?  197 ILE A HG21 1 
ATOM   1772 H HG22 . ILE A 1 116 ? 15.96945  -17.29217 -2.90415  1.000 15.54433  ?  197 ILE A HG22 1 
ATOM   1773 H HG23 . ILE A 1 116 ? 17.29752  -16.27340 -3.52451  1.000 15.54433  ?  197 ILE A HG23 1 
ATOM   1774 H HD11 . ILE A 1 116 ? 16.30519  -12.83073 -2.24214  1.000 19.75075  ?  197 ILE A HD11 1 
ATOM   1775 H HD12 . ILE A 1 116 ? 17.74119  -13.87481 -2.42738  1.000 19.75075  ?  197 ILE A HD12 1 
ATOM   1776 H HD13 . ILE A 1 116 ? 16.35968  -14.05081 -3.54405  1.000 19.75075  ?  197 ILE A HD13 1 
ATOM   1777 N N    . VAL A 1 117 ? 18.16723  -18.43164 0.25664   1.000 11.36630  ?  198 VAL A N    1 
ATOM   1778 C CA   . VAL A 1 117 ? 18.79047  -19.75017 0.37899   1.000 13.49851  ?  198 VAL A CA   1 
ATOM   1779 C C    . VAL A 1 117 ? 17.95284  -20.65987 1.27338   1.000 14.30480  ?  198 VAL A C    1 
ATOM   1780 O O    . VAL A 1 117 ? 17.77855  -21.85376 0.98103   1.000 16.02589  ?  198 VAL A O    1 
ATOM   1781 C CB   . VAL A 1 117 ? 20.24396  -19.62984 0.89599   1.000 14.55455  ?  198 VAL A CB   1 
ATOM   1782 C CG1  . VAL A 1 117 ? 20.78313  -20.98919 1.32289   1.000 18.52262  ?  198 VAL A CG1  1 
ATOM   1783 C CG2  . VAL A 1 117 ? 21.11983  -18.96046 -0.15173  1.000 16.07848  ?  198 VAL A CG2  1 
ATOM   1784 H H    A VAL A 1 117 ? 18.76170  -17.65780 0.55358   0.794 13.63956  ?  198 VAL A H    1 
ATOM   1785 D D    B VAL A 1 117 ? 18.76342  -17.65932 0.55411   0.206 13.63956  ?  198 VAL A D    1 
ATOM   1786 H HA   . VAL A 1 117 ? 18.82903  -20.19503 -0.61535  1.000 16.19821  ?  198 VAL A HA   1 
ATOM   1787 H HB   . VAL A 1 117 ? 20.26289  -18.99777 1.78381   1.000 17.46546  ?  198 VAL A HB   1 
ATOM   1788 H HG11 . VAL A 1 117 ? 21.27484  -21.45931 0.47124   1.000 22.22714  ?  198 VAL A HG11 1 
ATOM   1789 H HG12 . VAL A 1 117 ? 21.49788  -20.84874 2.13376   1.000 22.22714  ?  198 VAL A HG12 1 
ATOM   1790 H HG13 . VAL A 1 117 ? 19.95346  -21.60948 1.66200   1.000 22.22714  ?  198 VAL A HG13 1 
ATOM   1791 H HG21 . VAL A 1 117 ? 22.08522  -18.72020 0.29369   1.000 19.29417  ?  198 VAL A HG21 1 
ATOM   1792 H HG22 . VAL A 1 117 ? 21.25683  -19.64443 -0.98930  1.000 19.29417  ?  198 VAL A HG22 1 
ATOM   1793 H HG23 . VAL A 1 117 ? 20.63058  -18.04818 -0.49301  1.000 19.29417  ?  198 VAL A HG23 1 
ATOM   1794 N N    . ALA A 1 118 ? 17.42033  -20.11119 2.37211   1.000 13.09946  ?  199 ALA A N    1 
ATOM   1795 C CA   . ALA A 1 118 ? 16.65293  -20.93502 3.29232   1.000 16.88219  ?  199 ALA A CA   1 
ATOM   1796 C C    . ALA A 1 118 ? 15.39155  -21.48464 2.64504   1.000 16.92732  ?  199 ALA A C    1 
ATOM   1797 O O    . ALA A 1 118 ? 14.98531  -22.61544 2.93908   1.000 17.46250  ?  199 ALA A O    1 
ATOM   1798 C CB   . ALA A 1 118 ? 16.30370  -20.12462 4.53442   1.000 18.15128  ?  199 ALA A CB   1 
ATOM   1799 H H    A ALA A 1 118 ? 17.50346  -19.13017 2.63875   0.834 15.71935  ?  199 ALA A H    1 
ATOM   1800 D D    B ALA A 1 118 ? 17.50202  -19.13064 2.64092   0.166 15.71935  ?  199 ALA A D    1 
ATOM   1801 H HA   . ALA A 1 118 ? 17.26285  -21.78553 3.59684   1.000 20.25863  ?  199 ALA A HA   1 
ATOM   1802 H HB1  . ALA A 1 118 ? 17.20672  -19.64282 4.90927   1.000 21.78153  ?  199 ALA A HB1  1 
ATOM   1803 H HB2  . ALA A 1 118 ? 15.56270  -19.37046 4.26935   1.000 21.78153  ?  199 ALA A HB2  1 
ATOM   1804 H HB3  . ALA A 1 118 ? 15.89767  -20.79433 5.29252   1.000 21.78153  ?  199 ALA A HB3  1 
ATOM   1805 N N    . GLN A 1 119 ? 14.76870  -20.72551 1.73250   1.000 14.82240  ?  200 GLN A N    1 
ATOM   1806 C CA   . GLN A 1 119 ? 13.63704  -21.25027 0.97031   1.000 14.37039  ?  200 GLN A CA   1 
ATOM   1807 C C    . GLN A 1 119 ? 14.07810  -22.32549 -0.01877  1.000 15.40358  ?  200 GLN A C    1 
ATOM   1808 O O    . GLN A 1 119 ? 13.48814  -23.40421 -0.07910  1.000 16.55696  ?  200 GLN A O    1 
ATOM   1809 C CB   . GLN A 1 119 ? 12.93282  -20.10595 0.25912   1.000 14.37757  ?  200 GLN A CB   1 
ATOM   1810 C CG   . GLN A 1 119 ? 12.28466  -19.12365 1.17585   1.000 15.03984  ?  200 GLN A CG   1 
ATOM   1811 C CD   . GLN A 1 119 ? 11.07512  -19.69651 1.88939   1.000 21.46577  ?  200 GLN A CD   1 
ATOM   1812 O OE1  . GLN A 1 119 ? 10.60269  -20.77776 1.58360   1.000 20.29385  ?  200 GLN A OE1  1 
ATOM   1813 N NE2  . GLN A 1 119 ? 10.56037  -18.94188 2.84194   1.000 35.57264  ?  200 GLN A NE2  1 
ATOM   1814 H H    A GLN A 1 119 ? 15.02107  -19.76375 1.50506   0.896 17.78687  ?  200 GLN A H    1 
ATOM   1815 D D    B GLN A 1 119 ? 15.01931  -19.76367 1.50345   0.104 17.78687  ?  200 GLN A D    1 
ATOM   1816 H HA   . GLN A 1 119 ? 12.92902  -21.71453 1.65680   1.000 17.24447  ?  200 GLN A HA   1 
ATOM   1817 H HB2  . GLN A 1 119 ? 13.66479  -19.56534 -0.34094  1.000 17.25308  ?  200 GLN A HB2  1 
ATOM   1818 H HB3  . GLN A 1 119 ? 12.15648  -20.52036 -0.38404  1.000 17.25308  ?  200 GLN A HB3  1 
ATOM   1819 H HG2  . GLN A 1 119 ? 13.00622  -18.81349 1.93165   1.000 18.04780  ?  200 GLN A HG2  1 
ATOM   1820 H HG3  . GLN A 1 119 ? 11.95681  -18.26027 0.59689   1.000 18.04780  ?  200 GLN A HG3  1 
ATOM   1821 N N    . ILE A 1 120 ? 15.12075  -22.05212 -0.80351  1.000 13.52330  ?  201 ILE A N    1 
ATOM   1822 C CA   . ILE A 1 120 ? 15.52942  -22.98170 -1.85229  1.000 13.40161  ?  201 ILE A CA   1 
ATOM   1823 C C    . ILE A 1 120 ? 15.94788  -24.32113 -1.25841  1.000 14.30279  ?  201 ILE A C    1 
ATOM   1824 O O    . ILE A 1 120 ? 15.67156  -25.38737 -1.83476  1.000 15.98260  ?  201 ILE A O    1 
ATOM   1825 C CB   . ILE A 1 120 ? 16.64531  -22.32706 -2.70892  1.000 13.95754  ?  201 ILE A CB   1 
ATOM   1826 C CG1  . ILE A 1 120 ? 16.05970  -21.12640 -3.44598  1.000 15.11620  ?  201 ILE A CG1  1 
ATOM   1827 C CG2  . ILE A 1 120 ? 17.23659  -23.34516 -3.66919  1.000 15.68997  ?  201 ILE A CG2  1 
ATOM   1828 C CD1  . ILE A 1 120 ? 17.10228  -20.24447 -4.18376  1.000 17.40248  ?  201 ILE A CD1  1 
ATOM   1829 H H    A ILE A 1 120 ? 15.69283  -21.21010 -0.73932  0.982 16.22796  ?  201 ILE A H    1 
ATOM   1830 D D    B ILE A 1 120 ? 15.69415  -21.21086 -0.74111  0.018 16.22796  ?  201 ILE A D    1 
ATOM   1831 H HA   . ILE A 1 120 ? 14.68080  -23.18750 -2.50467  1.000 16.08194  ?  201 ILE A HA   1 
ATOM   1832 H HB   . ILE A 1 120 ? 17.45454  -21.98039 -2.06622  1.000 16.74904  ?  201 ILE A HB   1 
ATOM   1833 H HG12 . ILE A 1 120 ? 15.35156  -21.48935 -4.19090  1.000 18.13944  ?  201 ILE A HG12 1 
ATOM   1834 H HG13 . ILE A 1 120 ? 15.54738  -20.49235 -2.72238  1.000 18.13944  ?  201 ILE A HG13 1 
ATOM   1835 H HG21 . ILE A 1 120 ? 17.33344  -24.30212 -3.15641  1.000 18.82796  ?  201 ILE A HG21 1 
ATOM   1836 H HG22 . ILE A 1 120 ? 16.57392  -23.44922 -4.52834  1.000 18.82796  ?  201 ILE A HG22 1 
ATOM   1837 H HG23 . ILE A 1 120 ? 18.21671  -22.99754 -3.99569  1.000 18.82796  ?  201 ILE A HG23 1 
ATOM   1838 H HD11 . ILE A 1 120 ? 17.49107  -20.79576 -5.03993  1.000 20.88297  ?  201 ILE A HD11 1 
ATOM   1839 H HD12 . ILE A 1 120 ? 16.61720  -19.32836 -4.52070  1.000 20.88297  ?  201 ILE A HD12 1 
ATOM   1840 H HD13 . ILE A 1 120 ? 17.91369  -20.00437 -3.49668  1.000 20.88297  ?  201 ILE A HD13 1 
ATOM   1841 N N    . GLN A 1 121 ? 16.61647  -24.28933 -0.09857  1.000 16.07054  ?  202 GLN A N    1 
ATOM   1842 C CA   . GLN A 1 121 ? 17.10993  -25.49968 0.55218   1.000 15.60718  ?  202 GLN A CA   1 
ATOM   1843 C C    . GLN A 1 121 ? 16.01515  -26.48747 0.86125   1.000 18.89306  ?  202 GLN A C    1 
ATOM   1844 O O    . GLN A 1 121 ? 16.28021  -27.69366 0.98913   1.000 20.78133  ?  202 GLN A O    1 
ATOM   1845 C CB   . GLN A 1 121 ? 17.70016  -25.07613 1.89772   1.000 18.90311  ?  202 GLN A CB   1 
ATOM   1846 C CG   . GLN A 1 121 ? 18.93382  -25.73507 2.33185   1.000 50.15424  ?  202 GLN A CG   1 
ATOM   1847 C CD   . GLN A 1 121 ? 19.60337  -24.90783 3.40714   1.000 56.60993  ?  202 GLN A CD   1 
ATOM   1848 O OE1  . GLN A 1 121 ? 18.92772  -24.20509 4.17364   1.000 44.68597  ?  202 GLN A OE1  1 
ATOM   1849 N NE2  . GLN A 1 121 ? 20.93752  -24.95214 3.45157   1.000 67.15976  ?  202 GLN A NE2  1 
ATOM   1850 H H    A GLN A 1 121 ? 16.83199  -23.43521 0.41567   0.632 19.28465  ?  202 GLN A H    1 
ATOM   1851 D D    B GLN A 1 121 ? 16.83327  -23.43672 0.41763   0.368 19.28465  ?  202 GLN A D    1 
ATOM   1852 H HA   . GLN A 1 121 ? 17.83753  -25.97586 -0.10505  1.000 18.72861  ?  202 GLN A HA   1 
ATOM   1853 H HB2  . GLN A 1 121 ? 17.91448  -24.00860 1.84728   1.000 22.68373  ?  202 GLN A HB2  1 
ATOM   1854 H HB3  . GLN A 1 121 ? 16.95227  -25.27030 2.66653   1.000 22.68373  ?  202 GLN A HB3  1 
ATOM   1855 H HG2  . GLN A 1 121 ? 18.70197  -26.71923 2.73900   1.000 60.18508  ?  202 GLN A HG2  1 
ATOM   1856 H HG3  . GLN A 1 121 ? 19.61615  -25.83227 1.48741   1.000 60.18508  ?  202 GLN A HG3  1 
ATOM   1857 N N    . GLN A 1 122 ? 14.79098  -26.01074 1.00109   1.000 16.24076  ?  203 GLN A N    1 
ATOM   1858 C CA   . GLN A 1 122 ? 13.65845  -26.84371 1.41419   1.000 15.94187  ?  203 GLN A CA   1 
ATOM   1859 C C    . GLN A 1 122 ? 13.05278  -27.63070 0.27257   1.000 20.42300  ?  203 GLN A C    1 
ATOM   1860 O O    . GLN A 1 122 ? 12.25994  -28.54832 0.52062   1.000 19.57464  ?  203 GLN A O    1 
ATOM   1861 C CB   . GLN A 1 122 ? 12.57374  -25.95177 2.02026   1.000 17.62285  ?  203 GLN A CB   1 
ATOM   1862 C CG   . GLN A 1 122 ? 12.95994  -25.38239 3.36765   1.000 26.98029  ?  203 GLN A CG   1 
ATOM   1863 C CD   . GLN A 1 122 ? 11.91503  -24.41549 3.89393   1.000 34.81501  ?  203 GLN A CD   1 
ATOM   1864 O OE1  . GLN A 1 122 ? 10.72195  -24.72202 3.92922   1.000 42.12573  ?  203 GLN A OE1  1 
ATOM   1865 N NE2  . GLN A 1 122 ? 12.36283  -23.22900 4.27648   1.000 32.40820  ?  203 GLN A NE2  1 
ATOM   1866 H H    A GLN A 1 122 ? 14.53729  -25.03682 0.83517   0.564 19.48891  ?  203 GLN A H    1 
ATOM   1867 D D    B GLN A 1 122 ? 14.53707  -25.03687 0.83522   0.436 19.48891  ?  203 GLN A D    1 
ATOM   1868 H HA   . GLN A 1 122 ? 14.00259  -27.55320 2.16672   1.000 19.13024  ?  203 GLN A HA   1 
ATOM   1869 H HB2  . GLN A 1 122 ? 12.38371  -25.11769 1.34476   1.000 21.14742  ?  203 GLN A HB2  1 
ATOM   1870 H HB3  . GLN A 1 122 ? 11.66528  -26.53961 2.15155   1.000 21.14742  ?  203 GLN A HB3  1 
ATOM   1871 H HG2  . GLN A 1 122 ? 13.06350  -26.19649 4.08501   1.000 32.37635  ?  203 GLN A HG2  1 
ATOM   1872 H HG3  . GLN A 1 122 ? 13.90423  -24.84617 3.27341   1.000 32.37635  ?  203 GLN A HG3  1 
ATOM   1873 N N    . PHE A 1 123 ? 13.40504  -27.32186 -0.96690  1.000 16.93588  ?  204 PHE A N    1 
ATOM   1874 C CA   . PHE A 1 123 ? 12.82629  -27.98139 -2.13887  1.000 17.44461  ?  204 PHE A CA   1 
ATOM   1875 C C    . PHE A 1 123 ? 13.92377  -28.36840 -3.11007  1.000 17.34985  ?  204 PHE A C    1 
ATOM   1876 O O    . PHE A 1 123 ? 13.99912  -27.84400 -4.23012  1.000 18.14976  ?  204 PHE A O    1 
ATOM   1877 C CB   . PHE A 1 123 ? 11.78611  -27.07343 -2.79103  1.000 17.07049  ?  204 PHE A CB   1 
ATOM   1878 C CG   . PHE A 1 123 ? 10.66830  -26.72114 -1.86641  1.000 21.44470  ?  204 PHE A CG   1 
ATOM   1879 C CD1  . PHE A 1 123 ? 9.65383   -27.62351 -1.64595  1.000 24.35063  ?  204 PHE A CD1  1 
ATOM   1880 C CD2  . PHE A 1 123 ? 10.64820  -25.51220 -1.19741  1.000 26.83991  ?  204 PHE A CD2  1 
ATOM   1881 C CE1  . PHE A 1 123 ? 8.62009   -27.31763 -0.77801  1.000 22.85879  ?  204 PHE A CE1  1 
ATOM   1882 C CE2  . PHE A 1 123 ? 9.62586   -25.20160 -0.35115  1.000 31.80179  ?  204 PHE A CE2  1 
ATOM   1883 C CZ   . PHE A 1 123 ? 8.61607   -26.11230 -0.14073  1.000 27.71577  ?  204 PHE A CZ   1 
ATOM   1884 H H    A PHE A 1 123 ? 14.09770  -26.61005 -1.19918  0.563 20.32305  ?  204 PHE A H    1 
ATOM   1885 D D    B PHE A 1 123 ? 14.09806  -26.60956 -1.19658  0.437 20.32305  ?  204 PHE A D    1 
ATOM   1886 H HA   . PHE A 1 123 ? 12.34017  -28.90671 -1.82973  1.000 20.93353  ?  204 PHE A HA   1 
ATOM   1887 H HB2  . PHE A 1 123 ? 12.26927  -26.14810 -3.10475  1.000 20.48459  ?  204 PHE A HB2  1 
ATOM   1888 H HB3  . PHE A 1 123 ? 11.36131  -27.58381 -3.65541  1.000 20.48459  ?  204 PHE A HB3  1 
ATOM   1889 H HD1  . PHE A 1 123 ? 9.66404   -28.57681 -2.15340  1.000 29.22076  ?  204 PHE A HD1  1 
ATOM   1890 H HD2  . PHE A 1 123 ? 11.45133  -24.80573 -1.34672  1.000 32.20789  ?  204 PHE A HD2  1 
ATOM   1891 H HE1  . PHE A 1 123 ? 7.82399   -28.02714 -0.60710  1.000 27.43054  ?  204 PHE A HE1  1 
ATOM   1892 H HE2  . PHE A 1 123 ? 9.60847   -24.24587 0.15151   1.000 38.16215  ?  204 PHE A HE2  1 
ATOM   1893 H HZ   . PHE A 1 123 ? 7.81102   -25.86955 0.53704   1.000 33.25893  ?  204 PHE A HZ   1 
ATOM   1894 N N    . PRO A 1 124 ? 14.78379  -29.31301 -2.71916  1.000 19.12366  ?  205 PRO A N    1 
ATOM   1895 C CA   . PRO A 1 124 ? 15.88032  -29.71351 -3.58731  1.000 21.15647  ?  205 PRO A CA   1 
ATOM   1896 C C    . PRO A 1 124 ? 15.43568  -30.41784 -4.86104  1.000 18.70162  ?  205 PRO A C    1 
ATOM   1897 O O    . PRO A 1 124 ? 16.26827  -30.56072 -5.76917  1.000 21.11300  ?  205 PRO A O    1 
ATOM   1898 C CB   . PRO A 1 124 ? 16.68806  -30.65823 -2.70764  1.000 25.16886  ?  205 PRO A CB   1 
ATOM   1899 C CG   . PRO A 1 124 ? 15.70133  -31.18069 -1.77354  1.000 22.99260  ?  205 PRO A CG   1 
ATOM   1900 C CD   . PRO A 1 124 ? 14.74332  -30.10621 -1.48106  1.000 21.44939  ?  205 PRO A CD   1 
ATOM   1901 H HA   . PRO A 1 124 ? 16.48411  -28.84398 -3.84705  1.000 25.38777  ?  205 PRO A HA   1 
ATOM   1902 H HB2  . PRO A 1 124 ? 17.12411  -31.45514 -3.31005  1.000 30.20263  ?  205 PRO A HB2  1 
ATOM   1903 H HB3  . PRO A 1 124 ? 17.47447  -30.11080 -2.18803  1.000 30.20263  ?  205 PRO A HB3  1 
ATOM   1904 H HG2  . PRO A 1 124 ? 15.19011  -32.02852 -2.22955  1.000 27.59112  ?  205 PRO A HG2  1 
ATOM   1905 H HG3  . PRO A 1 124 ? 16.20498  -31.49649 -0.85992  1.000 27.59112  ?  205 PRO A HG3  1 
ATOM   1906 H HD2  . PRO A 1 124 ? 13.74535  -30.50686 -1.30320  1.000 25.73926  ?  205 PRO A HD2  1 
ATOM   1907 H HD3  . PRO A 1 124 ? 15.06564  -29.51449 -0.62428  1.000 25.73926  ?  205 PRO A HD3  1 
ATOM   1908 N N    . ASP A 1 125 ? 14.18270  -30.83414 -4.96842  1.000 18.04294  ?  206 ASP A N    1 
ATOM   1909 C CA   . ASP A 1 125 ? 13.67879  -31.44430 -6.18711  1.000 16.39177  ?  206 ASP A CA   1 
ATOM   1910 C C    . ASP A 1 125 ? 13.30268  -30.42355 -7.25377  1.000 15.54892  ?  206 ASP A C    1 
ATOM   1911 O O    . ASP A 1 125 ? 12.93557  -30.82165 -8.36740  1.000 19.02087  ?  206 ASP A O    1 
ATOM   1912 C CB   . ASP A 1 125 ? 12.44345  -32.31957 -5.88319  1.000 19.27645  ?  206 ASP A CB   1 
ATOM   1913 C CG   . ASP A 1 125 ? 11.35294  -31.54448 -5.19726  1.000 18.75121  ?  206 ASP A CG   1 
ATOM   1914 O OD1  . ASP A 1 125 ? 11.68624  -30.75504 -4.27467  1.000 22.67133  ?  206 ASP A OD1  1 
ATOM   1915 O OD2  . ASP A 1 125 ? 10.17866  -31.72886 -5.54390  1.000 25.96206  -1 206 ASP A OD2  1 
ATOM   1916 H H    A ASP A 1 125 ? 13.48872  -30.76208 -4.22438  0.606 21.65153  ?  206 ASP A H    1 
ATOM   1917 D D    B ASP A 1 125 ? 13.48903  -30.76189 -4.22411  0.394 21.65153  ?  206 ASP A D    1 
ATOM   1918 H HA   . ASP A 1 125 ? 14.46326  -32.08742 -6.58599  1.000 19.67012  ?  206 ASP A HA   1 
ATOM   1919 H HB2  . ASP A 1 125 ? 12.04447  -32.71212 -6.81851  1.000 23.13174  ?  206 ASP A HB2  1 
ATOM   1920 H HB3  . ASP A 1 125 ? 12.73892  -33.14073 -5.23013  1.000 23.13174  ?  206 ASP A HB3  1 
ATOM   1921 N N    . VAL A 1 126 ? 13.37351  -29.14257 -6.94745  1.000 13.74292  ?  207 VAL A N    1 
ATOM   1922 C CA   . VAL A 1 126 ? 13.05680  -28.08379 -7.89840  1.000 13.99915  ?  207 VAL A CA   1 
ATOM   1923 C C    . VAL A 1 126 ? 14.34802  -27.43258 -8.33716  1.000 13.77003  ?  207 VAL A C    1 
ATOM   1924 O O    . VAL A 1 126 ? 15.17145  -27.06441 -7.50041  1.000 17.14834  ?  207 VAL A O    1 
ATOM   1925 C CB   . VAL A 1 126 ? 12.10077  -27.04498 -7.29375  1.000 12.28365  ?  207 VAL A CB   1 
ATOM   1926 C CG1  . VAL A 1 126 ? 11.79699  -25.96223 -8.25509  1.000 16.17585  ?  207 VAL A CG1  1 
ATOM   1927 C CG2  . VAL A 1 126 ? 10.79241  -27.73776 -6.91032  1.000 18.61483  ?  207 VAL A CG2  1 
ATOM   1928 H H    A VAL A 1 126 ? 13.65268  -28.79466 -6.03015  0.779 16.49151  ?  207 VAL A H    1 
ATOM   1929 D D    B VAL A 1 126 ? 13.65300  -28.79724 -6.02928  0.221 16.49151  ?  207 VAL A D    1 
ATOM   1930 H HA   . VAL A 1 126 ? 12.57697  -28.52425 -8.77239  1.000 16.79898  ?  207 VAL A HA   1 
ATOM   1931 H HB   . VAL A 1 126 ? 12.57805  -26.60284 -6.41921  1.000 14.74038  ?  207 VAL A HB   1 
ATOM   1932 H HG11 . VAL A 1 126 ? 11.68100  -25.02564 -7.70970  1.000 19.41102  ?  207 VAL A HG11 1 
ATOM   1933 H HG12 . VAL A 1 126 ? 12.61840  -25.87869 -8.96671  1.000 19.41102  ?  207 VAL A HG12 1 
ATOM   1934 H HG13 . VAL A 1 126 ? 10.87296  -26.20320 -8.78064  1.000 19.41102  ?  207 VAL A HG13 1 
ATOM   1935 H HG21 . VAL A 1 126 ? 10.12989  -27.01032 -6.44128  1.000 22.33779  ?  207 VAL A HG21 1 
ATOM   1936 H HG22 . VAL A 1 126 ? 10.32631  -28.13896 -7.81026  1.000 22.33779  ?  207 VAL A HG22 1 
ATOM   1937 H HG23 . VAL A 1 126 ? 11.01023  -28.54628 -6.21249  1.000 22.33779  ?  207 VAL A HG23 1 
ATOM   1938 N N    . ARG A 1 127 ? 14.51982  -27.27537 -9.64400  1.000 11.67797  ?  208 ARG A N    1 
ATOM   1939 C CA   . ARG A 1 127 ? 15.69643  -26.56885 -10.15249 1.000 12.24737  ?  208 ARG A CA   1 
ATOM   1940 C C    . ARG A 1 127 ? 15.38917  -25.07853 -10.19894 1.000 10.98260  ?  208 ARG A C    1 
ATOM   1941 O O    . ARG A 1 127 ? 14.27541  -24.66931 -10.54735 1.000 13.90480  ?  208 ARG A O    1 
ATOM   1942 C CB   . ARG A 1 127 ? 16.05183  -27.05553 -11.53503 1.000 12.44619  ?  208 ARG A CB   1 
ATOM   1943 C CG   . ARG A 1 127 ? 17.22114  -26.29007 -12.12019 1.000 13.15136  ?  208 ARG A CG   1 
ATOM   1944 C CD   . ARG A 1 127 ? 17.79136  -27.02709 -13.29795 1.000 14.31165  ?  208 ARG A CD   1 
ATOM   1945 N NE   . ARG A 1 127 ? 18.56560  -28.17092 -12.85966 1.000 13.40279  ?  208 ARG A NE   1 
ATOM   1946 C CZ   . ARG A 1 127 ? 19.24839  -28.92721 -13.69680 1.000 13.99460  ?  208 ARG A CZ   1 
ATOM   1947 N NH1  . ARG A 1 127 ? 19.26413  -28.67849 -14.98634 1.000 14.75387  ?  208 ARG A NH1  1 
ATOM   1948 N NH2  . ARG A 1 127 ? 19.94809  -29.95137 -13.22095 1.000 18.32694  ?  208 ARG A NH2  1 
ATOM   1949 H H    A ARG A 1 127 ? 13.87962  -27.61621 -10.36120 0.636 14.01357  ?  208 ARG A H    1 
ATOM   1950 D D    B ARG A 1 127 ? 13.87920  -27.61647 -10.36071 0.364 14.01357  ?  208 ARG A D    1 
ATOM   1951 H HA   . ARG A 1 127 ? 16.55345  -26.74613 -9.50272  1.000 14.69684  ?  208 ARG A HA   1 
ATOM   1952 H HB2  . ARG A 1 127 ? 16.32434  -28.10973 -11.48490 1.000 14.93542  ?  208 ARG A HB2  1 
ATOM   1953 H HB3  . ARG A 1 127 ? 15.19318  -26.92333 -12.19331 1.000 14.93542  ?  208 ARG A HB3  1 
ATOM   1954 H HG2  . ARG A 1 127 ? 16.88559  -25.30803 -12.45352 1.000 15.78163  ?  208 ARG A HG2  1 
ATOM   1955 H HG3  . ARG A 1 127 ? 18.00128  -26.18155 -11.36672 1.000 15.78163  ?  208 ARG A HG3  1 
ATOM   1956 H HD2  . ARG A 1 127 ? 16.97997  -27.38081 -13.93405 1.000 17.17398  ?  208 ARG A HD2  1 
ATOM   1957 H HD3  . ARG A 1 127 ? 18.44476  -26.36189 -13.86248 1.000 17.17398  ?  208 ARG A HD3  1 
ATOM   1958 N N    . VAL A 1 128 ? 16.36833  -24.26400 -9.81954  1.000 10.84893  ?  209 VAL A N    1 
ATOM   1959 C CA   . VAL A 1 128 ? 16.23588  -22.80689 -9.83651  1.000 11.45324  ?  209 VAL A CA   1 
ATOM   1960 C C    . VAL A 1 128 ? 17.28988  -22.24735 -10.76096 1.000 11.63126  ?  209 VAL A C    1 
ATOM   1961 O O    . VAL A 1 128 ? 18.45370  -22.62339 -10.66624 1.000 11.11443  ?  209 VAL A O    1 
ATOM   1962 C CB   . VAL A 1 128 ? 16.36467  -22.20702 -8.42366  1.000 11.03907  ?  209 VAL A CB   1 
ATOM   1963 C CG1  . VAL A 1 128 ? 16.28606  -20.73897 -8.49060  1.000 12.03141  ?  209 VAL A CG1  1 
ATOM   1964 C CG2  . VAL A 1 128 ? 15.27652  -22.77799 -7.54944  1.000 15.13329  ?  209 VAL A CG2  1 
ATOM   1965 H H    A VAL A 1 128 ? 17.27835  -24.58658 -9.49060  0.672 13.01871  ?  209 VAL A H    1 
ATOM   1966 D D    B VAL A 1 128 ? 17.27758  -24.58909 -9.49094  0.328 13.01871  ?  209 VAL A D    1 
ATOM   1967 H HA   . VAL A 1 128 ? 15.25657  -22.53700 -10.23173 1.000 13.74389  ?  209 VAL A HA   1 
ATOM   1968 H HB   . VAL A 1 128 ? 17.32997  -22.46187 -7.98623  1.000 13.24689  ?  209 VAL A HB   1 
ATOM   1969 H HG11 . VAL A 1 128 ? 17.23588  -20.34905 -8.85654  1.000 14.43769  ?  209 VAL A HG11 1 
ATOM   1970 H HG12 . VAL A 1 128 ? 15.48195  -20.45728 -9.17043  1.000 14.43769  ?  209 VAL A HG12 1 
ATOM   1971 H HG13 . VAL A 1 128 ? 16.08348  -20.34859 -7.49327  1.000 14.43769  ?  209 VAL A HG13 1 
ATOM   1972 H HG21 . VAL A 1 128 ? 15.69891  -23.03159 -6.57713  1.000 18.15995  ?  209 VAL A HG21 1 
ATOM   1973 H HG22 . VAL A 1 128 ? 14.48975  -22.03311 -7.43006  1.000 18.15995  ?  209 VAL A HG22 1 
ATOM   1974 H HG23 . VAL A 1 128 ? 14.87273  -23.67235 -8.02398  1.000 18.15995  ?  209 VAL A HG23 1 
ATOM   1975 N N    . VAL A 1 129 ? 16.86880  -21.38792 -11.65876 1.000 9.85215   ?  210 VAL A N    1 
ATOM   1976 C CA   . VAL A 1 129 ? 17.76451  -20.58144 -12.49895 1.000 10.64051  ?  210 VAL A CA   1 
ATOM   1977 C C    . VAL A 1 129 ? 17.58266  -19.14096 -12.07132 1.000 10.58340  ?  210 VAL A C    1 
ATOM   1978 O O    . VAL A 1 129 ? 16.45009  -18.64582 -11.99925 1.000 11.45534  ?  210 VAL A O    1 
ATOM   1979 C CB   . VAL A 1 129 ? 17.46959  -20.75567 -14.00247 1.000 11.36244  ?  210 VAL A CB   1 
ATOM   1980 C CG1  . VAL A 1 129 ? 18.33617  -19.81838 -14.80784 1.000 14.03347  ?  210 VAL A CG1  1 
ATOM   1981 C CG2  . VAL A 1 129 ? 17.69513  -22.20079 -14.36699 1.000 15.75911  ?  210 VAL A CG2  1 
ATOM   1982 H H    A VAL A 1 129 ? 15.88187  -21.21056 -11.84565 0.995 11.82258  ?  210 VAL A H    1 
ATOM   1983 D D    B VAL A 1 129 ? 15.88117  -21.21244 -11.84369 0.005 11.82258  ?  210 VAL A D    1 
ATOM   1984 H HA   . VAL A 1 129 ? 18.79859  -20.88530 -12.33633 1.000 12.76862  ?  210 VAL A HA   1 
ATOM   1985 H HB   . VAL A 1 129 ? 16.43520  -20.50285 -14.23531 1.000 13.63493  ?  210 VAL A HB   1 
ATOM   1986 H HG11 . VAL A 1 129 ? 18.01895  -19.84929 -15.85020 1.000 16.84017  ?  210 VAL A HG11 1 
ATOM   1987 H HG12 . VAL A 1 129 ? 18.22553  -18.80749 -14.41546 1.000 16.84017  ?  210 VAL A HG12 1 
ATOM   1988 H HG13 . VAL A 1 129 ? 19.37526  -20.13724 -14.72592 1.000 16.84017  ?  210 VAL A HG13 1 
ATOM   1989 H HG21 . VAL A 1 129 ? 16.78510  -22.60001 -14.81483 1.000 18.91094  ?  210 VAL A HG21 1 
ATOM   1990 H HG22 . VAL A 1 129 ? 18.51802  -22.26289 -15.07910 1.000 18.91094  ?  210 VAL A HG22 1 
ATOM   1991 H HG23 . VAL A 1 129 ? 17.94158  -22.76013 -13.46449 1.000 18.91094  ?  210 VAL A HG23 1 
ATOM   1992 N N    . ALA A 1 130 ? 18.67016  -18.45424 -11.80246 1.000 9.96587   ?  211 ALA A N    1 
ATOM   1993 C CA   . ALA A 1 130 ? 18.63536  -17.07747 -11.32127 1.000 10.55038  ?  211 ALA A CA   1 
ATOM   1994 C C    . ALA A 1 130 ? 19.44186  -16.16202 -12.23593 1.000 11.18738  ?  211 ALA A C    1 
ATOM   1995 O O    . ALA A 1 130 ? 20.56934  -16.49272 -12.62583 1.000 13.47681  ?  211 ALA A O    1 
ATOM   1996 C CB   . ALA A 1 130 ? 19.17531  -16.94103 -9.91088  1.000 11.77831  ?  211 ALA A CB   1 
ATOM   1997 H H    A ALA A 1 130 ? 19.61475  -18.82455 -11.90746 1.000 11.95905  ?  211 ALA A H    1 
ATOM   1998 D D    B ALA A 1 130 ? 19.61388  -18.82656 -11.90819 0.000 11.95905  ?  211 ALA A D    1 
ATOM   1999 H HA   . ALA A 1 130 ? 17.59315  -16.75836 -11.32953 1.000 12.66045  ?  211 ALA A HA   1 
ATOM   2000 H HB1  . ALA A 1 130 ? 18.55932  -17.53536 -9.23603  1.000 14.13397  ?  211 ALA A HB1  1 
ATOM   2001 H HB2  . ALA A 1 130 ? 20.20417  -17.30026 -9.88848  1.000 14.13397  ?  211 ALA A HB2  1 
ATOM   2002 H HB3  . ALA A 1 130 ? 19.14153  -15.89168 -9.61793  1.000 14.13397  ?  211 ALA A HB3  1 
ATOM   2003 N N    . VAL A 1 131 ? 18.86061  -15.02942 -12.60281 1.000 10.11647  ?  212 VAL A N    1 
ATOM   2004 C CA   . VAL A 1 131 ? 19.59119  -13.88707 -13.13760 1.000 9.46619   ?  212 VAL A CA   1 
ATOM   2005 C C    . VAL A 1 131 ? 20.07124  -13.02384 -11.97027 1.000 9.58324   ?  212 VAL A C    1 
ATOM   2006 O O    . VAL A 1 131 ? 19.27351  -12.62861 -11.12414 1.000 10.94495  ?  212 VAL A O    1 
ATOM   2007 C CB   . VAL A 1 131 ? 18.73307  -13.06761 -14.10410 1.000 9.81124   ?  212 VAL A CB   1 
ATOM   2008 C CG1  . VAL A 1 131 ? 19.43481  -11.79220 -14.50938 1.000 10.90504  ?  212 VAL A CG1  1 
ATOM   2009 C CG2  . VAL A 1 131 ? 18.43275  -13.88602 -15.36757 1.000 11.59540  ?  212 VAL A CG2  1 
ATOM   2010 H H    A VAL A 1 131 ? 17.85572  -14.86592 -12.54055 1.000 12.13977  ?  212 VAL A H    1 
ATOM   2011 D D    B VAL A 1 131 ? 17.85556  -14.86710 -12.54007 0.000 12.13977  ?  212 VAL A D    1 
ATOM   2012 H HA   . VAL A 1 131 ? 20.45905  -14.25212 -13.68684 1.000 11.35943  ?  212 VAL A HA   1 
ATOM   2013 H HB   . VAL A 1 131 ? 17.80308  -12.81289 -13.59582 1.000 11.77349  ?  212 VAL A HB   1 
ATOM   2014 H HG11 . VAL A 1 131 ? 19.60240  -11.18196 -13.62191 1.000 13.08605  ?  212 VAL A HG11 1 
ATOM   2015 H HG12 . VAL A 1 131 ? 20.38866  -12.04389 -14.97297 1.000 13.08605  ?  212 VAL A HG12 1 
ATOM   2016 H HG13 . VAL A 1 131 ? 18.80775  -11.25219 -15.21881 1.000 13.08605  ?  212 VAL A HG13 1 
ATOM   2017 H HG21 . VAL A 1 131 ? 17.96000  -13.23833 -16.10588 1.000 13.91448  ?  212 VAL A HG21 1 
ATOM   2018 H HG22 . VAL A 1 131 ? 19.36756  -14.28177 -15.76457 1.000 13.91448  ?  212 VAL A HG22 1 
ATOM   2019 H HG23 . VAL A 1 131 ? 17.76241  -14.70556 -15.10853 1.000 13.91448  ?  212 VAL A HG23 1 
ATOM   2020 N N    . ILE A 1 132 ? 21.36679  -12.73239 -11.90247 1.000 8.94095   ?  213 ILE A N    1 
ATOM   2021 C CA   . ILE A 1 132 ? 21.95410  -12.02062 -10.77924 1.000 9.69967   ?  213 ILE A CA   1 
ATOM   2022 C C    . ILE A 1 132 ? 22.11079  -10.54614 -11.12862 1.000 11.25887  ?  213 ILE A C    1 
ATOM   2023 O O    . ILE A 1 132 ? 22.93260  -10.15267 -11.96183 1.000 10.55247  ?  213 ILE A O    1 
ATOM   2024 C CB   . ILE A 1 132 ? 23.31670  -12.63167 -10.38226 1.000 10.31577  ?  213 ILE A CB   1 
ATOM   2025 C CG1  . ILE A 1 132 ? 23.20250  -14.16157 -10.12407 1.000 12.91539  ?  213 ILE A CG1  1 
ATOM   2026 C CG2  . ILE A 1 132 ? 23.89272  -11.90301 -9.20887  1.000 12.28240  ?  213 ILE A CG2  1 
ATOM   2027 C CD1  . ILE A 1 132 ? 22.28200  -14.52792 -9.02330  1.000 16.23300  ?  213 ILE A CD1  1 
ATOM   2028 H H    A ILE A 1 132 ? 22.04269  -12.98214 -12.62440 1.000 10.72914  ?  213 ILE A H    1 
ATOM   2029 D D    B ILE A 1 132 ? 22.04103  -12.98311 -12.62562 0.000 10.72914  ?  213 ILE A D    1 
ATOM   2030 H HA   . ILE A 1 132 ? 21.25896  -12.08520 -9.94215  1.000 11.63961  ?  213 ILE A HA   1 
ATOM   2031 H HB   . ILE A 1 132 ? 24.00209  -12.50923 -11.22093 1.000 12.37892  ?  213 ILE A HB   1 
ATOM   2032 H HG12 . ILE A 1 132 ? 22.83799  -14.64142 -11.03236 1.000 15.49847  ?  213 ILE A HG12 1 
ATOM   2033 H HG13 . ILE A 1 132 ? 24.19021  -14.54617 -9.86989  1.000 15.49847  ?  213 ILE A HG13 1 
ATOM   2034 H HG21 . ILE A 1 132 ? 24.88551  -12.30001 -8.99710  1.000 14.73888  ?  213 ILE A HG21 1 
ATOM   2035 H HG22 . ILE A 1 132 ? 23.96008  -10.84178 -9.44835  1.000 14.73888  ?  213 ILE A HG22 1 
ATOM   2036 H HG23 . ILE A 1 132 ? 23.24233  -12.04888 -8.34642  1.000 14.73888  ?  213 ILE A HG23 1 
ATOM   2037 H HD11 . ILE A 1 132 ? 21.25514  -14.46392 -9.38326  1.000 19.47960  ?  213 ILE A HD11 1 
ATOM   2038 H HD12 . ILE A 1 132 ? 22.50049  -15.54635 -8.70211  1.000 19.47960  ?  213 ILE A HD12 1 
ATOM   2039 H HD13 . ILE A 1 132 ? 22.42865  -13.83685 -8.19324  1.000 19.47960  ?  213 ILE A HD13 1 
ATOM   2040 N N    . GLU A 1 133 ? 21.31461  -9.69494  -10.46215 1.000 9.33053   ?  214 GLU A N    1 
ATOM   2041 C CA   . GLU A 1 133 ? 21.45912  -8.25989  -10.35424 1.000 8.04021   ?  214 GLU A CA   1 
ATOM   2042 C C    . GLU A 1 133 ? 21.59385  -7.53584  -11.67073 1.000 9.99496   ?  214 GLU A C    1 
ATOM   2043 O O    . GLU A 1 133 ? 22.64096  -6.98998  -12.00102 1.000 10.73355  ?  214 GLU A O    1 
ATOM   2044 C CB   . GLU A 1 133 ? 22.52371  -7.91957  -9.35405  1.000 8.88544   ?  214 GLU A CB   1 
ATOM   2045 C CG   . GLU A 1 133 ? 22.21473  -8.38861  -7.92051  1.000 8.43300   ?  214 GLU A CG   1 
ATOM   2046 C CD   . GLU A 1 133 ? 21.10979  -7.67228  -7.23468  1.000 9.67450   ?  214 GLU A CD   1 
ATOM   2047 O OE1  . GLU A 1 133 ? 20.63683  -6.62343  -7.71723  1.000 10.91483  ?  214 GLU A OE1  1 
ATOM   2048 O OE2  . GLU A 1 133 ? 20.64858  -8.15732  -6.18092  1.000 10.37057  -1 214 GLU A OE2  1 
ATOM   2049 H H    A GLU A 1 133 ? 20.49334  -10.01151 -9.94669  0.973 11.19663  ?  214 GLU A H    1 
ATOM   2050 D D    B GLU A 1 133 ? 20.49339  -10.01171 -9.94675  0.027 11.19663  ?  214 GLU A D    1 
ATOM   2051 H HA   . GLU A 1 133 ? 20.51569  -7.86012  -9.98246  1.000 9.64825   ?  214 GLU A HA   1 
ATOM   2052 H HB2  . GLU A 1 133 ? 23.45612  -8.39207  -9.66299  1.000 10.66253  ?  214 GLU A HB2  1 
ATOM   2053 H HB3  . GLU A 1 133 ? 22.64501  -6.83663  -9.32890  1.000 10.66253  ?  214 GLU A HB3  1 
ATOM   2054 H HG2  . GLU A 1 133 ? 21.94301  -9.44359  -7.95615  1.000 10.11960  ?  214 GLU A HG2  1 
ATOM   2055 H HG3  . GLU A 1 133 ? 23.11140  -8.25482  -7.31537  1.000 10.11960  ?  214 GLU A HG3  1 
ATOM   2056 N N    . PRO A 1 134 ? 20.49399  -7.39610  -12.40109 1.000 9.58372   ?  215 PRO A N    1 
ATOM   2057 C CA   . PRO A 1 134 ? 20.48323  -6.47236  -13.51543 1.000 9.80843   ?  215 PRO A CA   1 
ATOM   2058 C C    . PRO A 1 134 ? 20.93371  -5.08709  -13.08673 1.000 11.25972  ?  215 PRO A C    1 
ATOM   2059 O O    . PRO A 1 134 ? 20.70386  -4.63564  -11.98360 1.000 11.56527  ?  215 PRO A O    1 
ATOM   2060 C CB   . PRO A 1 134 ? 19.01152  -6.44268  -13.94566 1.000 12.44853  ?  215 PRO A CB   1 
ATOM   2061 C CG   . PRO A 1 134 ? 18.42721  -7.68929  -13.41544 1.000 12.89548  ?  215 PRO A CG   1 
ATOM   2062 C CD   . PRO A 1 134 ? 19.18673  -7.97670  -12.14704 1.000 11.19193  ?  215 PRO A CD   1 
ATOM   2063 H HA   . PRO A 1 134 ? 21.11107  -6.84702  -14.32385 1.000 11.77011  ?  215 PRO A HA   1 
ATOM   2064 H HB2  . PRO A 1 134 ? 18.51875  -5.56943  -13.51822 1.000 14.93823  ?  215 PRO A HB2  1 
ATOM   2065 H HB3  . PRO A 1 134 ? 18.94462  -6.41343  -15.03321 1.000 14.93823  ?  215 PRO A HB3  1 
ATOM   2066 H HG2  . PRO A 1 134 ? 17.36719  -7.54233  -13.20839 1.000 15.47458  ?  215 PRO A HG2  1 
ATOM   2067 H HG3  . PRO A 1 134 ? 18.55779  -8.49549  -14.13730 1.000 15.47458  ?  215 PRO A HG3  1 
ATOM   2068 H HD2  . PRO A 1 134 ? 18.70923  -7.49800  -11.29210 1.000 13.43032  ?  215 PRO A HD2  1 
ATOM   2069 H HD3  . PRO A 1 134 ? 19.26562  -9.05047  -11.97705 1.000 13.43032  ?  215 PRO A HD3  1 
ATOM   2070 N N    . ASP A 1 135 ? 21.54586  -4.37067  -14.02564 1.000 10.25975  ?  216 ASP A N    1 
ATOM   2071 C CA   . ASP A 1 135 ? 21.91185  -2.96701  -13.84886 1.000 12.03359  ?  216 ASP A CA   1 
ATOM   2072 C C    . ASP A 1 135 ? 22.86042  -2.78891  -12.66281 1.000 12.62202  ?  216 ASP A C    1 
ATOM   2073 O O    . ASP A 1 135 ? 22.71754  -1.84541  -11.89927 1.000 12.81669  ?  216 ASP A O    1 
ATOM   2074 C CB   . ASP A 1 135 ? 20.68083  -2.07635  -13.67380 1.000 12.48537  ?  216 ASP A CB   1 
ATOM   2075 C CG   . ASP A 1 135 ? 20.99957  -0.61517  -13.80549 1.000 12.65538  ?  216 ASP A CG   1 
ATOM   2076 O OD1  . ASP A 1 135 ? 21.90898  -0.26127  -14.53786 1.000 14.82712  ?  216 ASP A OD1  1 
ATOM   2077 O OD2  . ASP A 1 135 ? 20.29699  0.19384   -13.12996 1.000 14.76513  -1 216 ASP A OD2  1 
ATOM   2078 H H    A ASP A 1 135 ? 21.80744  -4.74143  -14.93916 0.816 12.31170  ?  216 ASP A H    1 
ATOM   2079 D D    B ASP A 1 135 ? 21.80709  -4.74226  -14.93892 0.184 12.31170  ?  216 ASP A D    1 
ATOM   2080 H HA   . ASP A 1 135 ? 22.43178  -2.64661  -14.75170 1.000 14.44031  ?  216 ASP A HA   1 
ATOM   2081 H HB2  . ASP A 1 135 ? 19.94601  -2.33148  -14.43737 1.000 14.98244  ?  216 ASP A HB2  1 
ATOM   2082 H HB3  . ASP A 1 135 ? 20.26050  -2.24186  -12.68182 1.000 14.98244  ?  216 ASP A HB3  1 
ATOM   2083 N N    . SER A 1 136 ? 23.83504  -3.69821  -12.51011 1.000 12.33177  ?  217 SER A N    1 
ATOM   2084 C CA   . SER A 1 136 ? 24.79741  -3.62275  -11.41485 1.000 10.95658  ?  217 SER A CA   1 
ATOM   2085 C C    . SER A 1 136 ? 26.20955  -3.54539  -11.96481 1.000 11.46261  ?  217 SER A C    1 
ATOM   2086 O O    . SER A 1 136 ? 26.73402  -2.44786  -12.18987 1.000 12.38161  ?  217 SER A O    1 
ATOM   2087 C CB   . SER A 1 136 ? 24.60074  -4.76402  -10.42666 1.000 11.55421  ?  217 SER A CB   1 
ATOM   2088 O OG   . SER A 1 136 ? 24.89816  -6.02305  -10.94679 1.000 12.96089  ?  217 SER A OG   1 
ATOM   2089 H H    A SER A 1 136 ? 23.97860  -4.49486  -13.13070 0.613 14.79812  ?  217 SER A H    1 
ATOM   2090 D D    B SER A 1 136 ? 23.97884  -4.49495  -13.13053 0.387 14.79812  ?  217 SER A D    1 
ATOM   2091 H HA   . SER A 1 136 ? 24.63327  -2.71297  -10.83740 1.000 13.14790  ?  217 SER A HA   1 
ATOM   2092 H HB2  . SER A 1 136 ? 25.25045  -4.58774  -9.56939  1.000 13.86505  ?  217 SER A HB2  1 
ATOM   2093 H HB3  . SER A 1 136 ? 23.55771  -4.76423  -10.11012 1.000 13.86505  ?  217 SER A HB3  1 
ATOM   2094 N N    . LEU A 1 137 ? 26.80758  -4.69777  -12.23562 1.000 11.04735  ?  218 LEU A N    1 
ATOM   2095 C CA   . LEU A 1 137 ? 28.23076  -4.71273  -12.59065 1.000 12.69689  ?  218 LEU A CA   1 
ATOM   2096 C C    . LEU A 1 137 ? 28.52279  -3.99818  -13.90925 1.000 12.32377  ?  218 LEU A C    1 
ATOM   2097 O O    . LEU A 1 137 ? 29.62397  -3.48783  -14.08080 1.000 12.56774  ?  218 LEU A O    1 
ATOM   2098 C CB   . LEU A 1 137 ? 28.71455  -6.17063  -12.69024 1.000 15.94021  ?  218 LEU A CB   1 
ATOM   2099 C CG   . LEU A 1 137 ? 28.56776  -6.98690  -11.40952 1.000 16.09516  ?  218 LEU A CG   1 
ATOM   2100 C CD1  . LEU A 1 137 ? 29.08051  -8.39168  -11.67141 1.000 18.60402  ?  218 LEU A CD1  1 
ATOM   2101 C CD2  . LEU A 1 137 ? 29.25151  -6.30290  -10.26772 1.000 20.59965  ?  218 LEU A CD2  1 
ATOM   2102 H H    A LEU A 1 137 ? 26.35655  -5.61251  -12.22067 0.901 13.25682  ?  218 LEU A H    1 
ATOM   2103 D D    B LEU A 1 137 ? 26.35879  -5.61362  -12.22134 0.099 13.25682  ?  218 LEU A D    1 
ATOM   2104 H HA   . LEU A 1 137 ? 28.77876  -4.19314  -11.80464 1.000 15.23627  ?  218 LEU A HA   1 
ATOM   2105 H HB2  . LEU A 1 137 ? 28.13742  -6.67266  -13.46676 1.000 19.12826  ?  218 LEU A HB2  1 
ATOM   2106 H HB3  . LEU A 1 137 ? 29.77162  -6.16526  -12.95606 1.000 19.12826  ?  218 LEU A HB3  1 
ATOM   2107 H HG   . LEU A 1 137 ? 27.52365  -7.07147  -11.10821 1.000 19.31419  ?  218 LEU A HG   1 
ATOM   2108 H HD11 . LEU A 1 137 ? 30.17020  -8.37397  -11.69012 1.000 22.32482  ?  218 LEU A HD11 1 
ATOM   2109 H HD12 . LEU A 1 137 ? 28.73308  -9.05040  -10.87549 1.000 22.32482  ?  218 LEU A HD12 1 
ATOM   2110 H HD13 . LEU A 1 137 ? 28.69780  -8.73575  -12.63227 1.000 22.32482  ?  218 LEU A HD13 1 
ATOM   2111 H HD21 . LEU A 1 137 ? 28.80696  -5.31773  -10.12661 1.000 24.71958  ?  218 LEU A HD21 1 
ATOM   2112 H HD22 . LEU A 1 137 ? 29.12186  -6.90178  -9.36626  1.000 24.71958  ?  218 LEU A HD22 1 
ATOM   2113 H HD23 . LEU A 1 137 ? 30.31219  -6.20256  -10.49795 1.000 24.71958  ?  218 LEU A HD23 1 
ATOM   2114 N N    . ALA A 1 138 ? 27.57151  -3.94292  -14.85588 1.000 10.82705  ?  219 ALA A N    1 
ATOM   2115 C CA   . ALA A 1 138 ? 27.83959  -3.23215  -16.08903 1.000 10.98459  ?  219 ALA A CA   1 
ATOM   2116 C C    . ALA A 1 138 ? 28.16479  -1.78455  -15.79369 1.000 13.87012  ?  219 ALA A C    1 
ATOM   2117 O O    . ALA A 1 138 ? 28.94457  -1.17075  -16.54203 1.000 13.27980  ?  219 ALA A O    1 
ATOM   2118 C CB   . ALA A 1 138 ? 26.61851  -3.36275  -16.98152 1.000 13.26358  ?  219 ALA A CB   1 
ATOM   2119 H H    A ALA A 1 138 ? 26.64633  -4.36720  -14.78941 0.711 12.99245  ?  219 ALA A H    1 
ATOM   2120 D D    B ALA A 1 138 ? 26.64574  -4.36629  -14.79180 0.289 12.99245  ?  219 ALA A D    1 
ATOM   2121 H HA   . ALA A 1 138 ? 28.69174  -3.65648  -16.61995 1.000 13.18150  ?  219 ALA A HA   1 
ATOM   2122 H HB1  . ALA A 1 138 ? 25.95530  -4.12180  -16.56667 1.000 15.91630  ?  219 ALA A HB1  1 
ATOM   2123 H HB2  . ALA A 1 138 ? 26.10460  -2.40239  -17.02256 1.000 15.91630  ?  219 ALA A HB2  1 
ATOM   2124 H HB3  . ALA A 1 138 ? 26.93933  -3.65567  -17.98121 1.000 15.91630  ?  219 ALA A HB3  1 
ATOM   2125 N N    . ASN A 1 139 ? 27.60482  -1.19597  -14.70383 1.000 12.85886  ?  220 ASN A N    1 
ATOM   2126 C CA   . ASN A 1 139 ? 27.94922  0.17256   -14.35953 1.000 12.70462  ?  220 ASN A CA   1 
ATOM   2127 C C    . ASN A 1 139 ? 29.40063  0.33555   -13.95114 1.000 14.77366  ?  220 ASN A C    1 
ATOM   2128 O O    . ASN A 1 139 ? 29.92651  1.44967   -14.01984 1.000 14.54369  ?  220 ASN A O    1 
ATOM   2129 C CB   . ASN A 1 139 ? 27.11202  0.64893   -13.18470 1.000 12.70533  ?  220 ASN A CB   1 
ATOM   2130 C CG   . ASN A 1 139 ? 25.65944  0.83137   -13.52970 1.000 15.15892  ?  220 ASN A CG   1 
ATOM   2131 O OD1  . ASN A 1 139 ? 25.27433  1.70620   -14.29488 1.000 15.08377  ?  220 ASN A OD1  1 
ATOM   2132 N ND2  . ASN A 1 139 ? 24.81256  -0.04078  -12.95265 1.000 19.18159  ?  220 ASN A ND2  1 
ATOM   2133 H H    A ASN A 1 139 ? 26.93604  -1.64111  -14.07535 0.753 15.43063  ?  220 ASN A H    1 
ATOM   2134 D D    B ASN A 1 139 ? 26.93594  -1.63893  -14.07392 0.247 15.43063  ?  220 ASN A D    1 
ATOM   2135 H HA   . ASN A 1 139 ? 27.74921  0.77144   -15.24803 1.000 15.24555  ?  220 ASN A HA   1 
ATOM   2136 H HB2  . ASN A 1 139 ? 27.17637  -0.08698  -12.38321 1.000 15.24640  ?  220 ASN A HB2  1 
ATOM   2137 H HB3  . ASN A 1 139 ? 27.49818  1.60870   -12.84145 1.000 15.24640  ?  220 ASN A HB3  1 
ATOM   2138 N N    . LEU A 1 140 ? 30.04177  -0.71777  -13.47398 1.000 13.31461  ?  221 LEU A N    1 
ATOM   2139 C CA   . LEU A 1 140 ? 31.43651  -0.63224  -13.06552 1.000 12.78244  ?  221 LEU A CA   1 
ATOM   2140 C C    . LEU A 1 140 ? 32.37277  -0.66076  -14.24241 1.000 16.66292  ?  221 LEU A C    1 
ATOM   2141 O O    . LEU A 1 140 ? 33.56147  -0.39375  -14.07680 1.000 21.05765  ?  221 LEU A O    1 
ATOM   2142 C CB   . LEU A 1 140 ? 31.79291  -1.71856  -12.04922 1.000 15.52890  ?  221 LEU A CB   1 
ATOM   2143 C CG   . LEU A 1 140 ? 30.79805  -1.78352  -10.87486 1.000 17.24299  ?  221 LEU A CG   1 
ATOM   2144 C CD1  . LEU A 1 140 ? 31.17181  -2.89860  -9.90288  1.000 19.62213  ?  221 LEU A CD1  1 
ATOM   2145 C CD2  . LEU A 1 140 ? 30.67383  -0.44867  -10.15248 1.000 20.05362  ?  221 LEU A CD2  1 
ATOM   2146 H H    A LEU A 1 140 ? 29.62701  -1.64230  -13.35731 0.935 15.97753  ?  221 LEU A H    1 
ATOM   2147 D D    B LEU A 1 140 ? 29.62721  -1.64238  -13.35723 0.065 15.97753  ?  221 LEU A D    1 
ATOM   2148 H HA   . LEU A 1 140 ? 31.59057  0.31070   -12.54090 1.000 15.33893  ?  221 LEU A HA   1 
ATOM   2149 H HB2  . LEU A 1 140 ? 31.78943  -2.68683  -12.54976 1.000 18.63468  ?  221 LEU A HB2  1 
ATOM   2150 H HB3  . LEU A 1 140 ? 32.78315  -1.51245  -11.64297 1.000 18.63468  ?  221 LEU A HB3  1 
ATOM   2151 H HG   . LEU A 1 140 ? 29.81456  -2.01051  -11.28635 1.000 20.69159  ?  221 LEU A HG   1 
ATOM   2152 H HD11 . LEU A 1 140 ? 30.27207  -3.23894  -9.39031  1.000 23.54656  ?  221 LEU A HD11 1 
ATOM   2153 H HD12 . LEU A 1 140 ? 31.61541  -3.72261  -10.46175 1.000 23.54656  ?  221 LEU A HD12 1 
ATOM   2154 H HD13 . LEU A 1 140 ? 31.88874  -2.51233  -9.17838  1.000 23.54656  ?  221 LEU A HD13 1 
ATOM   2155 H HD21 . LEU A 1 140 ? 31.47018  0.21383   -10.49163 1.000 24.06434  ?  221 LEU A HD21 1 
ATOM   2156 H HD22 . LEU A 1 140 ? 29.70262  -0.01014  -10.38171 1.000 24.06434  ?  221 LEU A HD22 1 
ATOM   2157 H HD23 . LEU A 1 140 ? 30.76185  -0.61652  -9.07908  1.000 24.06434  ?  221 LEU A HD23 1 
ATOM   2158 N N    . VAL A 1 141 ? 31.86964  -0.96341  -15.43659 1.000 13.34760  ?  222 VAL A N    1 
ATOM   2159 C CA   . VAL A 1 141 ? 32.70853  -0.85625  -16.63808 1.000 14.53687  ?  222 VAL A CA   1 
ATOM   2160 C C    . VAL A 1 141 ? 32.67758  0.55522   -17.21082 1.000 16.31898  ?  222 VAL A C    1 
ATOM   2161 O O    . VAL A 1 141 ? 33.73074  1.11070   -17.52697 1.000 22.33870  ?  222 VAL A O    1 
ATOM   2162 C CB   . VAL A 1 141 ? 32.28075  -1.90018  -17.65924 1.000 16.53615  ?  222 VAL A CB   1 
ATOM   2163 C CG1  . VAL A 1 141 ? 33.18324  -1.82478  -18.88820 1.000 18.83835  ?  222 VAL A CG1  1 
ATOM   2164 C CG2  . VAL A 1 141 ? 32.32699  -3.26216  -17.03419 1.000 19.48499  ?  222 VAL A CG2  1 
ATOM   2165 H H    A VAL A 1 141 ? 30.91395  -1.27700  -15.60602 0.677 16.01712  ?  222 VAL A H    1 
ATOM   2166 D D    B VAL A 1 141 ? 30.91407  -1.27704  -15.60666 0.323 16.01712  ?  222 VAL A D    1 
ATOM   2167 H HA   . VAL A 1 141 ? 33.74260  -1.06883  -16.36675 1.000 17.44424  ?  222 VAL A HA   1 
ATOM   2168 H HB   . VAL A 1 141 ? 31.25785  -1.70995  -17.98420 1.000 19.84338  ?  222 VAL A HB   1 
ATOM   2169 H HG11 . VAL A 1 141 ? 32.82192  -2.52906  -19.63756 1.000 22.60602  ?  222 VAL A HG11 1 
ATOM   2170 H HG12 . VAL A 1 141 ? 33.15553  -0.81080  -19.28715 1.000 22.60602  ?  222 VAL A HG12 1 
ATOM   2171 H HG13 . VAL A 1 141 ? 34.20164  -2.08191  -18.59692 1.000 22.60602  ?  222 VAL A HG13 1 
ATOM   2172 H HG21 . VAL A 1 141 ? 32.11289  -4.01034  -17.79740 1.000 23.38198  ?  222 VAL A HG21 1 
ATOM   2173 H HG22 . VAL A 1 141 ? 33.32103  -3.42855  -16.61909 1.000 23.38198  ?  222 VAL A HG22 1 
ATOM   2174 H HG23 . VAL A 1 141 ? 31.57990  -3.31472  -16.24224 1.000 23.38198  ?  222 VAL A HG23 1 
ATOM   2175 N N    . THR A 1 142 ? 31.49439  1.15585   -17.33101 1.000 13.44869  ?  223 THR A N    1 
ATOM   2176 C CA   . THR A 1 142 ? 31.34964  2.39980   -18.07677 1.000 14.63834  ?  223 THR A CA   1 
ATOM   2177 C C    . THR A 1 142 ? 30.95012  3.60670   -17.25341 1.000 17.99887  ?  223 THR A C    1 
ATOM   2178 O O    . THR A 1 142 ? 31.01471  4.72333   -17.77602 1.000 20.25304  ?  223 THR A O    1 
ATOM   2179 C CB   . THR A 1 142 ? 30.32754  2.24129   -19.21336 1.000 15.62293  ?  223 THR A CB   1 
ATOM   2180 O OG1  . THR A 1 142 ? 29.02231  2.04588   -18.67085 1.000 16.58309  ?  223 THR A OG1  1 
ATOM   2181 C CG2  . THR A 1 142 ? 30.66308  1.06698   -20.10846 1.000 17.90274  ?  223 THR A CG2  1 
ATOM   2182 H H    A THR A 1 142 ? 30.62639  0.80591   -16.92540 0.593 16.13842  ?  223 THR A H    1 
ATOM   2183 D D    B THR A 1 142 ? 30.62687  0.80515   -16.92503 0.407 16.13842  ?  223 THR A D    1 
ATOM   2184 H HA   . THR A 1 142 ? 32.32438  2.61653   -18.51382 1.000 17.56601  ?  223 THR A HA   1 
ATOM   2185 H HB   . THR A 1 142 ? 30.34833  3.14678   -19.81980 1.000 18.74752  ?  223 THR A HB   1 
ATOM   2186 H HG21 . THR A 1 142 ? 31.49411  0.50194   -19.68630 1.000 21.48329  ?  223 THR A HG21 1 
ATOM   2187 H HG22 . THR A 1 142 ? 29.79868  0.40937   -20.20040 1.000 21.48329  ?  223 THR A HG22 1 
ATOM   2188 H HG23 . THR A 1 142 ? 30.94429  1.42228   -21.09982 1.000 21.48329  ?  223 THR A HG23 1 
ATOM   2189 N N    . ASN A 1 143 ? 30.52693  3.43765   -16.00687 1.000 14.40789  ?  224 ASN A N    1 
ATOM   2190 C CA   . ASN A 1 143 ? 29.90321  4.49911   -15.23656 1.000 14.71909  ?  224 ASN A CA   1 
ATOM   2191 C C    . ASN A 1 143 ? 30.64769  4.82364   -13.93724 1.000 13.83202  ?  224 ASN A C    1 
ATOM   2192 O O    . ASN A 1 143 ? 30.03624  5.36600   -13.02259 1.000 15.75487  ?  224 ASN A O    1 
ATOM   2193 C CB   . ASN A 1 143 ? 28.43073  4.17005   -14.95114 1.000 14.44604  ?  224 ASN A CB   1 
ATOM   2194 C CG   . ASN A 1 143 ? 27.57459  4.33256   -16.12286 1.000 21.25866  ?  224 ASN A CG   1 
ATOM   2195 O OD1  . ASN A 1 143 ? 27.88393  5.11181   -17.02701 1.000 26.42965  ?  224 ASN A OD1  1 
ATOM   2196 N ND2  . ASN A 1 143 ? 26.44589  3.62296   -16.15278 1.000 17.21273  ?  224 ASN A ND2  1 
ATOM   2197 H H    A ASN A 1 143 ? 30.60530  2.55813   -15.49629 0.769 17.28947  ?  224 ASN A H    1 
ATOM   2198 D D    B ASN A 1 143 ? 30.60618  2.55727   -15.49790 0.231 17.28947  ?  224 ASN A D    1 
ATOM   2199 H HA   . ASN A 1 143 ? 29.94394  5.40366   -15.84338 1.000 17.66291  ?  224 ASN A HA   1 
ATOM   2200 H HB2  . ASN A 1 143 ? 28.35646  3.13376   -14.62146 1.000 17.33524  ?  224 ASN A HB2  1 
ATOM   2201 H HB3  . ASN A 1 143 ? 28.06322  4.83670   -14.17100 1.000 17.33524  ?  224 ASN A HB3  1 
ATOM   2202 N N    . LEU A 1 144 ? 31.95879  4.56522   -13.87636 1.000 14.46757  ?  225 LEU A N    1 
ATOM   2203 C CA   . LEU A 1 144 ? 32.70283  4.91238   -12.66760 1.000 15.87010  ?  225 LEU A CA   1 
ATOM   2204 C C    . LEU A 1 144 ? 32.90856  6.41146   -12.46400 1.000 16.37707  ?  225 LEU A C    1 
ATOM   2205 O O    . LEU A 1 144 ? 33.29767  6.81184   -11.36803 1.000 20.76761  ?  225 LEU A O    1 
ATOM   2206 C CB   . LEU A 1 144 ? 34.06385  4.21539   -12.62106 1.000 17.12786  ?  225 LEU A CB   1 
ATOM   2207 C CG   . LEU A 1 144 ? 33.98455  2.70739   -12.43760 1.000 21.73150  ?  225 LEU A CG   1 
ATOM   2208 C CD1  . LEU A 1 144 ? 35.32949  2.08807   -12.50365 1.000 24.50391  ?  225 LEU A CD1  1 
ATOM   2209 C CD2  . LEU A 1 144 ? 33.28995  2.39562   -11.13491 1.000 25.53415  ?  225 LEU A CD2  1 
ATOM   2210 H H    A LEU A 1 144 ? 32.50918  4.13375   -14.61886 0.652 17.36108  ?  225 LEU A H    1 
ATOM   2211 D D    B LEU A 1 144 ? 32.50995  4.13381   -14.61832 0.348 17.36108  ?  225 LEU A D    1 
ATOM   2212 H HA   . LEU A 1 144 ? 32.10836  4.54082   -11.83294 1.000 19.04412  ?  225 LEU A HA   1 
ATOM   2213 H HB2  . LEU A 1 144 ? 34.58593  4.40849   -13.55821 1.000 20.55343  ?  225 LEU A HB2  1 
ATOM   2214 H HB3  . LEU A 1 144 ? 34.63446  4.62157   -11.78588 1.000 20.55343  ?  225 LEU A HB3  1 
ATOM   2215 H HG   . LEU A 1 144 ? 33.40308  2.26879   -13.24854 1.000 26.07780  ?  225 LEU A HG   1 
ATOM   2216 H HD11 . LEU A 1 144 ? 35.80140  2.15913   -11.52367 1.000 29.40469  ?  225 LEU A HD11 1 
ATOM   2217 H HD12 . LEU A 1 144 ? 35.22468  1.04180   -12.79074 1.000 29.40469  ?  225 LEU A HD12 1 
ATOM   2218 H HD13 . LEU A 1 144 ? 35.92843  2.61844   -13.24396 1.000 29.40469  ?  225 LEU A HD13 1 
ATOM   2219 H HD21 . LEU A 1 144 ? 33.77314  2.95343   -10.33274 1.000 30.64098  ?  225 LEU A HD21 1 
ATOM   2220 H HD22 . LEU A 1 144 ? 32.24270  2.68781   -11.21235 1.000 30.64098  ?  225 LEU A HD22 1 
ATOM   2221 H HD23 . LEU A 1 144 ? 33.36392  1.32565   -10.94051 1.000 30.64098  ?  225 LEU A HD23 1 
ATOM   2222 N N    . ASN A 1 145 ? 32.61771  7.24905   -13.45626 1.000 15.81467  ?  226 ASN A N    1 
ATOM   2223 C CA   . ASN A 1 145 ? 32.60691  8.68371   -13.19993 1.000 17.27127  ?  226 ASN A CA   1 
ATOM   2224 C C    . ASN A 1 145 ? 31.32172  9.17683   -12.57550 1.000 21.60447  ?  226 ASN A C    1 
ATOM   2225 O O    . ASN A 1 145 ? 31.24559  10.35611  -12.21080 1.000 24.30031  ?  226 ASN A O    1 
ATOM   2226 C CB   . ASN A 1 145 ? 32.81829  9.44046   -14.50001 1.000 21.18525  ?  226 ASN A CB   1 
ATOM   2227 C CG   . ASN A 1 145 ? 34.24566  9.41324   -14.91767 1.000 33.66868  ?  226 ASN A CG   1 
ATOM   2228 O OD1  . ASN A 1 145 ? 35.18196  9.53637   -14.10630 1.000 27.50833  ?  226 ASN A OD1  1 
ATOM   2229 N ND2  . ASN A 1 145 ? 34.43791  9.24152   -16.22047 1.000 37.08202  ?  226 ASN A ND2  1 
ATOM   2230 H H    A ASN A 1 145 ? 32.39376  6.97371   -14.41252 0.762 18.97760  ?  226 ASN A H    1 
ATOM   2231 D D    B ASN A 1 145 ? 32.39373  6.97391   -14.41257 0.238 18.97760  ?  226 ASN A D    1 
ATOM   2232 H HA   . ASN A 1 145 ? 33.42568  8.90532   -12.51539 1.000 20.72552  ?  226 ASN A HA   1 
ATOM   2233 H HB2  . ASN A 1 145 ? 32.22121  8.97991   -15.28708 1.000 25.42230  ?  226 ASN A HB2  1 
ATOM   2234 H HB3  . ASN A 1 145 ? 32.51952  10.48004  -14.36537 1.000 25.42230  ?  226 ASN A HB3  1 
ATOM   2235 N N    . VAL A 1 146 ? 30.30118  8.32451   -12.44809 1.000 15.26179  ?  227 VAL A N    1 
ATOM   2236 C CA   . VAL A 1 146 ? 29.12626  8.63800   -11.65029 1.000 15.89264  ?  227 VAL A CA   1 
ATOM   2237 C C    . VAL A 1 146 ? 29.48764  8.38030   -10.19589 1.000 17.99326  ?  227 VAL A C    1 
ATOM   2238 O O    . VAL A 1 146 ? 29.82706  7.24465   -9.81170  1.000 15.78493  ?  227 VAL A O    1 
ATOM   2239 C CB   . VAL A 1 146 ? 27.93956  7.77078   -12.05229 1.000 16.76505  ?  227 VAL A CB   1 
ATOM   2240 C CG1  . VAL A 1 146 ? 26.69617  8.21049   -11.26657 1.000 19.70092  ?  227 VAL A CG1  1 
ATOM   2241 C CG2  . VAL A 1 146 ? 27.69425  7.83487   -13.55227 1.000 19.20971  ?  227 VAL A CG2  1 
ATOM   2242 H H    A VAL A 1 146 ? 30.26440  7.40594   -12.88999 0.830 18.31415  ?  227 VAL A H    1 
ATOM   2243 D D    B VAL A 1 146 ? 30.26457  7.40597   -12.89007 0.170 18.31415  ?  227 VAL A D    1 
ATOM   2244 H HA   . VAL A 1 146 ? 28.85525  9.68437   -11.79089 1.000 19.07117  ?  227 VAL A HA   1 
ATOM   2245 H HB   . VAL A 1 146 ? 28.15557  6.72989   -11.81147 1.000 20.11806  ?  227 VAL A HB   1 
ATOM   2246 H HG11 . VAL A 1 146 ? 26.09062  7.33287   -11.04033 1.000 23.64111  ?  227 VAL A HG11 1 
ATOM   2247 H HG12 . VAL A 1 146 ? 27.01293  8.69206   -10.34144 1.000 23.64111  ?  227 VAL A HG12 1 
ATOM   2248 H HG13 . VAL A 1 146 ? 26.12268  8.91149   -11.87305 1.000 23.64111  ?  227 VAL A HG13 1 
ATOM   2249 H HG21 . VAL A 1 146 ? 27.87205  6.84965   -13.98334 1.000 23.05165  ?  227 VAL A HG21 1 
ATOM   2250 H HG22 . VAL A 1 146 ? 26.66249  8.13788   -13.73049 1.000 23.05165  ?  227 VAL A HG22 1 
ATOM   2251 H HG23 . VAL A 1 146 ? 28.37653  8.56193   -13.99269 1.000 23.05165  ?  227 VAL A HG23 1 
ATOM   2252 N N    . GLN A 1 147 ? 29.43662  9.44260   -9.36695  1.000 18.66937  ?  228 GLN A N    1 
ATOM   2253 C CA   . GLN A 1 147 ? 29.94630  9.30998   -8.01403  1.000 18.46132  ?  228 GLN A CA   1 
ATOM   2254 C C    . GLN A 1 147 ? 29.22587  8.21186   -7.24651  1.000 16.99566  ?  228 GLN A C    1 
ATOM   2255 O O    . GLN A 1 147 ? 29.85039  7.45799   -6.49880  1.000 17.29274  ?  228 GLN A O    1 
ATOM   2256 C CB   . GLN A 1 147 ? 29.81137  10.62294  -7.27284  1.000 25.23680  ?  228 GLN A CB   1 
ATOM   2257 C CG   . GLN A 1 147 ? 30.04314  10.45839  -5.76676  1.000 72.31083  ?  228 GLN A CG   1 
ATOM   2258 C CD   . GLN A 1 147 ? 30.75259  11.64253  -5.14466  1.000 102.17181 ?  228 GLN A CD   1 
ATOM   2259 O OE1  . GLN A 1 147 ? 31.72462  12.16259  -5.70344  1.000 92.30880  ?  228 GLN A OE1  1 
ATOM   2260 N NE2  . GLN A 1 147 ? 30.26893  12.07780  -3.97766  1.000 101.11227 ?  228 GLN A NE2  1 
ATOM   2261 H H    A GLN A 1 147 ? 29.06255  10.36120  -9.60494  0.586 22.40324  ?  228 GLN A H    1 
ATOM   2262 D D    B GLN A 1 147 ? 29.06311  10.36205  -9.60253  0.414 22.40324  ?  228 GLN A D    1 
ATOM   2263 H HA   . GLN A 1 147 ? 31.00302  9.04980   -8.07528  1.000 22.15359  ?  228 GLN A HA   1 
ATOM   2264 H HB2  . GLN A 1 147 ? 30.54878  11.32803  -7.65647  1.000 30.28415  ?  228 GLN A HB2  1 
ATOM   2265 H HB3  . GLN A 1 147 ? 28.80604  11.01673  -7.42228  1.000 30.28415  ?  228 GLN A HB3  1 
ATOM   2266 H HG2  . GLN A 1 147 ? 29.07934  10.34552  -5.27034  1.000 86.77299  ?  228 GLN A HG2  1 
ATOM   2267 H HG3  . GLN A 1 147 ? 30.65572  9.57286   -5.59735  1.000 86.77299  ?  228 GLN A HG3  1 
ATOM   2268 N N    . LYS A 1 148 ? 27.91507  8.10731   -7.41493  1.000 16.82518  ?  229 LYS A N    1 
ATOM   2269 C CA   . LYS A 1 148 ? 27.17858  7.05663   -6.71609  1.000 17.19557  ?  229 LYS A CA   1 
ATOM   2270 C C    . LYS A 1 148 ? 27.67766  5.66064   -7.10250  1.000 15.59465  ?  229 LYS A C    1 
ATOM   2271 O O    . LYS A 1 148 ? 27.69996  4.76188   -6.25342  1.000 16.75864  ?  229 LYS A O    1 
ATOM   2272 C CB   . LYS A 1 148 ? 25.67956  7.19882   -6.98936  1.000 17.77169  ?  229 LYS A CB   1 
ATOM   2273 C CG   . LYS A 1 148 ? 24.82645  6.24694   -6.15623  1.000 20.41610  ?  229 LYS A CG   1 
ATOM   2274 C CD   . LYS A 1 148 ? 23.36219  6.63920   -6.20658  1.000 24.45791  ?  229 LYS A CD   1 
ATOM   2275 C CE   . LYS A 1 148 ? 22.50181  5.68197   -5.41661  1.000 28.21919  ?  229 LYS A CE   1 
ATOM   2276 N NZ   . LYS A 1 148 ? 21.06051  5.88328   -5.70329  1.000 31.50807  ?  229 LYS A NZ   1 
ATOM   2277 H H    A LYS A 1 148 ? 27.34736  8.71245   -8.00815  0.673 20.19021  ?  229 LYS A H    1 
ATOM   2278 D D    B LYS A 1 148 ? 27.34520  8.71108   -8.00747  0.327 20.19021  ?  229 LYS A D    1 
ATOM   2279 H HA   . LYS A 1 148 ? 27.33119  7.17099   -5.64290  1.000 20.63469  ?  229 LYS A HA   1 
ATOM   2280 H HB2  . LYS A 1 148 ? 25.37275  8.21800   -6.75433  1.000 21.32603  ?  229 LYS A HB2  1 
ATOM   2281 H HB3  . LYS A 1 148 ? 25.49053  6.98584   -8.04151  1.000 21.32603  ?  229 LYS A HB3  1 
ATOM   2282 H HG2  . LYS A 1 148 ? 24.92536  5.23443   -6.54756  1.000 24.49933  ?  229 LYS A HG2  1 
ATOM   2283 H HG3  . LYS A 1 148 ? 25.15606  6.27911   -5.11776  1.000 24.49933  ?  229 LYS A HG3  1 
ATOM   2284 H HD2  . LYS A 1 148 ? 23.24140  7.63641   -5.78342  1.000 29.34950  ?  229 LYS A HD2  1 
ATOM   2285 H HD3  . LYS A 1 148 ? 23.02193  6.62990   -7.24207  1.000 29.34950  ?  229 LYS A HD3  1 
ATOM   2286 H HE2  . LYS A 1 148 ? 22.76428  4.65784   -5.68187  1.000 33.86303  ?  229 LYS A HE2  1 
ATOM   2287 H HE3  . LYS A 1 148 ? 22.66541  5.84477   -4.35133  1.000 33.86303  ?  229 LYS A HE3  1 
ATOM   2288 N N    . CYS A 1 149 ? 28.08526  5.46118   -8.34542  1.000 13.51126  ?  230 CYS A N    1 
ATOM   2289 C CA   . CYS A 1 149 ? 28.61043  4.17247   -8.76672  1.000 13.98027  ?  230 CYS A CA   1 
ATOM   2290 C C    . CYS A 1 149 ? 30.01051  3.93960   -8.23582  1.000 14.40873  ?  230 CYS A C    1 
ATOM   2291 O O    . CYS A 1 149 ? 30.32171  2.83245   -7.78451  1.000 14.72251  ?  230 CYS A O    1 
ATOM   2292 C CB   . CYS A 1 149 ? 28.63706  4.03744   -10.30359 1.000 14.38266  ?  230 CYS A CB   1 
ATOM   2293 S SG   . CYS A 1 149 ? 26.96396  4.03145   -11.07508 1.000 13.87257  ?  230 CYS A SG   1 
ATOM   2294 H H    A CYS A 1 149 ? 28.06590  6.16633   -9.08216  0.657 16.21352  ?  230 CYS A H    1 
ATOM   2295 D D    B CYS A 1 149 ? 28.06672  6.16492   -9.08352  0.343 16.21352  ?  230 CYS A D    1 
ATOM   2296 H HA   . CYS A 1 149 ? 27.93529  3.41242   -8.37353  1.000 16.77632  ?  230 CYS A HA   1 
ATOM   2297 H HB2  . CYS A 1 149 ? 29.19291  4.87763   -10.71977 1.000 17.25919  ?  230 CYS A HB2  1 
ATOM   2298 H HB3  . CYS A 1 149 ? 29.12777  3.09982   -10.56469 1.000 17.25919  ?  230 CYS A HB3  1 
ATOM   2299 N N    . ALA A 1 150 ? 30.88362  4.95468   -8.30666  1.000 13.94970  ?  231 ALA A N    1 
ATOM   2300 C CA   . ALA A 1 150 ? 32.22927  4.79915   -7.75412  1.000 15.38026  ?  231 ALA A CA   1 
ATOM   2301 C C    . ALA A 1 150 ? 32.16381  4.45903   -6.26732  1.000 15.34268  ?  231 ALA A C    1 
ATOM   2302 O O    . ALA A 1 150 ? 32.88613  3.57858   -5.78963  1.000 17.38528  ?  231 ALA A O    1 
ATOM   2303 C CB   . ALA A 1 150 ? 33.02234  6.07337   -7.98148  1.000 17.95680  ?  231 ALA A CB   1 
ATOM   2304 H H    A ALA A 1 150 ? 30.69357  5.86471   -8.72635  0.793 16.73964  ?  231 ALA A H    1 
ATOM   2305 D D    B ALA A 1 150 ? 30.69604  5.86549   -8.72575  0.207 16.73964  ?  231 ALA A D    1 
ATOM   2306 H HA   . ALA A 1 150 ? 32.74377  3.98578   -8.26579  1.000 18.45631  ?  231 ALA A HA   1 
ATOM   2307 H HB1  . ALA A 1 150 ? 32.73255  6.50560   -8.93923  1.000 21.54816  ?  231 ALA A HB1  1 
ATOM   2308 H HB2  . ALA A 1 150 ? 32.80516  6.77500   -7.17609  1.000 21.54816  ?  231 ALA A HB2  1 
ATOM   2309 H HB3  . ALA A 1 150 ? 34.08552  5.83314   -7.98856  1.000 21.54816  ?  231 ALA A HB3  1 
ATOM   2310 N N    . ASN A 1 151 ? 31.24996  5.10508   -5.53679  1.000 16.26428  ?  232 ASN A N    1 
ATOM   2311 C CA   . ASN A 1 151 ? 31.11464  4.84535   -4.11436  1.000 16.63205  ?  232 ASN A CA   1 
ATOM   2312 C C    . ASN A 1 151 ? 30.50019  3.48717   -3.85149  1.000 18.99498  ?  232 ASN A C    1 
ATOM   2313 O O    . ASN A 1 151 ? 30.72570  2.91667   -2.77686  1.000 21.23111  ?  232 ASN A O    1 
ATOM   2314 C CB   . ASN A 1 151 ? 30.24459  5.90693   -3.44331  1.000 23.28686  ?  232 ASN A CB   1 
ATOM   2315 C CG   . ASN A 1 151 ? 31.00457  7.22468   -3.24877  1.000 49.77320  ?  232 ASN A CG   1 
ATOM   2316 O OD1  . ASN A 1 151 ? 32.23612  7.25736   -3.32238  1.000 38.53514  ?  232 ASN A OD1  1 
ATOM   2317 N ND2  . ASN A 1 151 ? 30.26773  8.30915   -3.01019  1.000 59.42680  ?  232 ASN A ND2  1 
ATOM   2318 H H    A ASN A 1 151 ? 30.60126  5.80255   -5.90165  0.762 19.51714  ?  232 ASN A H    1 
ATOM   2319 D D    B ASN A 1 151 ? 30.60054  5.80276   -5.89996  0.238 19.51714  ?  232 ASN A D    1 
ATOM   2320 H HA   . ASN A 1 151 ? 32.10819  4.89105   -3.66842  1.000 19.95846  ?  232 ASN A HA   1 
ATOM   2321 H HB2  . ASN A 1 151 ? 29.37268  6.10404   -4.06702  1.000 27.94423  ?  232 ASN A HB2  1 
ATOM   2322 H HB3  . ASN A 1 151 ? 29.92882  5.54668   -2.46422  1.000 27.94423  ?  232 ASN A HB3  1 
ATOM   2323 N N    . ALA A 1 152 ? 29.74974  2.93778   -4.80395  1.000 16.66756  ?  233 ALA A N    1 
ATOM   2324 C CA   . ALA A 1 152 ? 29.09178  1.65717   -4.56566  1.000 13.44773  ?  233 ALA A CA   1 
ATOM   2325 C C    . ALA A 1 152 ? 29.92651  0.47950   -5.03751  1.000 15.86838  ?  233 ALA A C    1 
ATOM   2326 O O    . ALA A 1 152 ? 29.55082  -0.66120  -4.75554  1.000 16.03677  ?  233 ALA A O    1 
ATOM   2327 C CB   . ALA A 1 152 ? 27.74530  1.59959   -5.30776  1.000 17.12744  ?  233 ALA A CB   1 
ATOM   2328 H H    A ALA A 1 152 ? 29.58370  3.34453   -5.72449  0.725 20.00107  ?  233 ALA A H    1 
ATOM   2329 D D    B ALA A 1 152 ? 29.58407  3.34504   -5.72433  0.275 20.00107  ?  233 ALA A D    1 
ATOM   2330 H HA   . ALA A 1 152 ? 28.90562  1.56415   -3.49571  1.000 16.13728  ?  233 ALA A HA   1 
ATOM   2331 H HB1  . ALA A 1 152 ? 27.17952  0.73929   -4.95016  1.000 20.55293  ?  233 ALA A HB1  1 
ATOM   2332 H HB2  . ALA A 1 152 ? 27.19137  2.51719   -5.10960  1.000 20.55293  ?  233 ALA A HB2  1 
ATOM   2333 H HB3  . ALA A 1 152 ? 27.93329  1.50245   -6.37702  1.000 20.55293  ?  233 ALA A HB3  1 
ATOM   2334 N N    . LYS A 1 153 ? 31.06476  0.71817   -5.71564  1.000 15.13227  ?  234 LYS A N    1 
ATOM   2335 C CA   . LYS A 1 153 ? 31.78183  -0.35374  -6.39040  1.000 13.55759  ?  234 LYS A CA   1 
ATOM   2336 C C    . LYS A 1 153 ? 32.09893  -1.51994  -5.45188  1.000 14.69924  ?  234 LYS A C    1 
ATOM   2337 O O    . LYS A 1 153 ? 31.79627  -2.66974  -5.77092  1.000 15.36136  ?  234 LYS A O    1 
ATOM   2338 C CB   . LYS A 1 153 ? 33.07342  0.20385   -6.99245  1.000 15.75918  ?  234 LYS A CB   1 
ATOM   2339 C CG   . LYS A 1 153 ? 33.94689  -0.85144  -7.63533  1.000 18.53923  ?  234 LYS A CG   1 
ATOM   2340 C CD   . LYS A 1 153 ? 35.23101  -0.25932  -8.19309  1.000 30.06825  ?  234 LYS A CD   1 
ATOM   2341 C CE   . LYS A 1 153 ? 36.24746  -1.36764  -8.45049  1.000 48.11958  ?  234 LYS A CE   1 
ATOM   2342 N NZ   . LYS A 1 153 ? 37.44900  -0.91037  -9.17289  1.000 55.48418  ?  234 LYS A NZ   1 
ATOM   2343 H H    A LYS A 1 153 ? 31.50170  1.63512   -5.80879  0.735 18.15872  ?  234 LYS A H    1 
ATOM   2344 D D    B LYS A 1 153 ? 31.50332  1.63422   -5.81001  0.265 18.15872  ?  234 LYS A D    1 
ATOM   2345 H HA   . LYS A 1 153 ? 31.14870  -0.74055  -7.18892  1.000 16.26911  ?  234 LYS A HA   1 
ATOM   2346 H HB2  . LYS A 1 153 ? 32.81646  0.93589   -7.75807  1.000 18.91102  ?  234 LYS A HB2  1 
ATOM   2347 H HB3  . LYS A 1 153 ? 33.65277  0.67966   -6.20121  1.000 18.91102  ?  234 LYS A HB3  1 
ATOM   2348 H HG2  . LYS A 1 153 ? 34.21263  -1.60118  -6.89011  1.000 22.24708  ?  234 LYS A HG2  1 
ATOM   2349 H HG3  . LYS A 1 153 ? 33.40204  -1.31821  -8.45592  1.000 22.24708  ?  234 LYS A HG3  1 
ATOM   2350 H HD2  . LYS A 1 153 ? 35.02265  0.24958   -9.13420  1.000 36.08190  ?  234 LYS A HD2  1 
ATOM   2351 H HD3  . LYS A 1 153 ? 35.65399  0.44326   -7.47505  1.000 36.08190  ?  234 LYS A HD3  1 
ATOM   2352 H HE2  . LYS A 1 153 ? 36.57041  -1.77800  -7.49372  1.000 57.74349  ?  234 LYS A HE2  1 
ATOM   2353 H HE3  . LYS A 1 153 ? 35.77505  -2.14608  -9.04962  1.000 57.74349  ?  234 LYS A HE3  1 
ATOM   2354 N N    . THR A 1 154 ? 32.74090  -1.25215  -4.30218  1.000 14.56046  ?  235 THR A N    1 
ATOM   2355 C CA   A THR A 1 154 ? 33.15576  -2.36893  -3.46960  0.558 15.81386  ?  235 THR A CA   1 
ATOM   2356 C CA   B THR A 1 154 ? 33.15173  -2.31626  -3.39610  0.442 16.02460  ?  235 THR A CA   1 
ATOM   2357 C C    . THR A 1 154 ? 31.95298  -3.08838  -2.86988  1.000 14.49896  ?  235 THR A C    1 
ATOM   2358 O O    . THR A 1 154 ? 32.00739  -4.31650  -2.71599  1.000 16.00436  ?  235 THR A O    1 
ATOM   2359 C CB   A THR A 1 154 ? 34.16788  -1.89738  -2.40559  0.558 20.96736  ?  235 THR A CB   1 
ATOM   2360 C CB   B THR A 1 154 ? 33.90242  -1.67688  -2.21343  0.442 19.62514  ?  235 THR A CB   1 
ATOM   2361 O OG1  A THR A 1 154 ? 33.58050  -0.84893  -1.62859  0.558 20.05782  ?  235 THR A OG1  1 
ATOM   2362 O OG1  B THR A 1 154 ? 34.96182  -0.84742  -2.68665  0.442 22.25976  ?  235 THR A OG1  1 
ATOM   2363 C CG2  A THR A 1 154 ? 35.48469  -1.44269  -3.07190  0.558 15.81444  ?  235 THR A CG2  1 
ATOM   2364 C CG2  B THR A 1 154 ? 34.47876  -2.73906  -1.29468  0.442 21.39270  ?  235 THR A CG2  1 
ATOM   2365 H H    A THR A 1 154 ? 32.97040  -0.32315  -3.94906  0.650 17.47255  ?  235 THR A H    1 
ATOM   2366 D D    B THR A 1 154 ? 32.98603  -0.31659  -3.97807  0.350 17.47255  ?  235 THR A D    1 
ATOM   2367 H HA   A THR A 1 154 ? 33.68496  -3.10485  -4.07497  0.558 18.97664  ?  235 THR A HA   1 
ATOM   2368 H HA   B THR A 1 154 ? 33.80189  -3.01378  -3.92417  0.442 19.22952  ?  235 THR A HA   1 
ATOM   2369 H HB   A THR A 1 154 ? 34.42475  -2.71623  -1.73357  0.558 25.16084  ?  235 THR A HB   1 
ATOM   2370 H HB   B THR A 1 154 ? 33.19736  -1.07149  -1.64379  0.442 23.55017  ?  235 THR A HB   1 
ATOM   2371 H HG1  A THR A 1 154 ? 32.76164  -0.52918  -2.06174  0.558 24.06939  ?  235 THR A HG1  1 
ATOM   2372 H HG1  B THR A 1 154 ? 35.72137  -1.40031  -2.96557  0.442 26.71172  ?  235 THR A HG1  1 
ATOM   2373 H HG21 A THR A 1 154 ? 35.65664  -0.38467  -2.87409  0.558 18.97732  ?  235 THR A HG21 1 
ATOM   2374 H HG21 B THR A 1 154 ? 34.33743  -3.72722  -1.73246  0.442 25.67124  ?  235 THR A HG21 1 
ATOM   2375 H HG22 A THR A 1 154 ? 36.32135  -2.01737  -2.67462  0.558 18.97732  ?  235 THR A HG22 1 
ATOM   2376 H HG22 B THR A 1 154 ? 35.54494  -2.56638  -1.14789  0.442 25.67124  ?  235 THR A HG22 1 
ATOM   2377 H HG23 A THR A 1 154 ? 35.42976  -1.59671  -4.14957  0.558 18.97732  ?  235 THR A HG23 1 
ATOM   2378 H HG23 B THR A 1 154 ? 33.97853  -2.70611  -0.32681  0.442 25.67124  ?  235 THR A HG23 1 
ATOM   2379 N N    . THR A 1 155 ? 30.86558  -2.37246  -2.55638  1.000 14.01164  ?  236 THR A N    1 
ATOM   2380 C CA   . THR A 1 155 ? 29.66530  -3.02512  -2.05899  1.000 12.30542  ?  236 THR A CA   1 
ATOM   2381 C C    . THR A 1 155 ? 29.01298  -3.88321  -3.14481  1.000 14.60129  ?  236 THR A C    1 
ATOM   2382 O O    . THR A 1 155 ? 28.54098  -5.00158  -2.87213  1.000 13.91406  ?  236 THR A O    1 
ATOM   2383 C CB   . THR A 1 155 ? 28.68170  -1.98887  -1.55472  1.000 15.81020  ?  236 THR A CB   1 
ATOM   2384 O OG1  . THR A 1 155 ? 29.29354  -1.24103  -0.48578  1.000 18.57299  ?  236 THR A OG1  1 
ATOM   2385 C CG2  . THR A 1 155 ? 27.41126  -2.62581  -1.03189  1.000 16.72644  ?  236 THR A CG2  1 
ATOM   2386 H H    A THR A 1 155 ? 30.79273  -1.35825  -2.63673  0.710 16.81397  ?  236 THR A H    1 
ATOM   2387 D D    B THR A 1 155 ? 30.79049  -1.35834  -2.63592  0.290 16.81397  ?  236 THR A D    1 
ATOM   2388 H HA   . THR A 1 155 ? 29.94233  -3.67289  -1.22728  1.000 14.76650  ?  236 THR A HA   1 
ATOM   2389 H HB   . THR A 1 155 ? 28.41071  -1.33207  -2.38133  1.000 18.97224  ?  236 THR A HB   1 
ATOM   2390 H HG21 . THR A 1 155 ? 26.77353  -2.92336  -1.86428  1.000 20.07173  ?  236 THR A HG21 1 
ATOM   2391 H HG22 . THR A 1 155 ? 27.65316  -3.50773  -0.43875  1.000 20.07173  ?  236 THR A HG22 1 
ATOM   2392 H HG23 . THR A 1 155 ? 26.86880  -1.91679  -0.40650  1.000 20.07173  ?  236 THR A HG23 1 
ATOM   2393 N N    . TYR A 1 156 ? 28.88588  -3.34580  -4.37181  1.000 12.61835  ?  237 TYR A N    1 
ATOM   2394 C CA   . TYR A 1 156 ? 28.33474  -4.15476  -5.45076  1.000 11.69947  ?  237 TYR A CA   1 
ATOM   2395 C C    . TYR A 1 156 ? 29.12976  -5.45351  -5.60435  1.000 12.63150  ?  237 TYR A C    1 
ATOM   2396 O O    . TYR A 1 156 ? 28.55900  -6.53424  -5.71833  1.000 11.78304  ?  237 TYR A O    1 
ATOM   2397 C CB   . TYR A 1 156 ? 28.38131  -3.37547  -6.76486  1.000 12.51110  ?  237 TYR A CB   1 
ATOM   2398 C CG   . TYR A 1 156 ? 27.26011  -2.41415  -7.04628  1.000 12.85079  ?  237 TYR A CG   1 
ATOM   2399 C CD1  . TYR A 1 156 ? 26.37162  -1.96796  -6.05579  1.000 11.40298  ?  237 TYR A CD1  1 
ATOM   2400 C CD2  . TYR A 1 156 ? 27.06663  -1.93812  -8.35243  1.000 12.40173  ?  237 TYR A CD2  1 
ATOM   2401 C CE1  . TYR A 1 156 ? 25.36725  -1.09025  -6.35085  1.000 11.81528  ?  237 TYR A CE1  1 
ATOM   2402 C CE2  . TYR A 1 156 ? 26.03276  -1.03663  -8.65430  1.000 13.23445  ?  237 TYR A CE2  1 
ATOM   2403 C CZ   . TYR A 1 156 ? 25.22008  -0.61669  -7.63950  1.000 12.09477  ?  237 TYR A CZ   1 
ATOM   2404 O OH   . TYR A 1 156 ? 24.19809  0.30752   -7.97536  1.000 13.69865  ?  237 TYR A OH   1 
ATOM   2405 H H    A TYR A 1 156 ? 29.14680  -2.39401  -4.62952  1.000 15.14202  ?  237 TYR A H    1 
ATOM   2406 D D    B TYR A 1 156 ? 29.14617  -2.39438  -4.63152  0.000 15.14202  ?  237 TYR A D    1 
ATOM   2407 H HA   . TYR A 1 156 ? 27.29583  -4.38940  -5.21902  1.000 14.03937  ?  237 TYR A HA   1 
ATOM   2408 H HB2  . TYR A 1 156 ? 29.30319  -2.79399  -6.77505  1.000 15.01332  ?  237 TYR A HB2  1 
ATOM   2409 H HB3  . TYR A 1 156 ? 28.38730  -4.09810  -7.58087  1.000 15.01332  ?  237 TYR A HB3  1 
ATOM   2410 H HD1  . TYR A 1 156 ? 26.48386  -2.32473  -5.04262  1.000 13.68357  ?  237 TYR A HD1  1 
ATOM   2411 H HD2  . TYR A 1 156 ? 27.72549  -2.27148  -9.14057  1.000 14.88208  ?  237 TYR A HD2  1 
ATOM   2412 H HE1  . TYR A 1 156 ? 24.68813  -0.76665  -5.57595  1.000 14.17833  ?  237 TYR A HE1  1 
ATOM   2413 H HE2  . TYR A 1 156 ? 25.88379  -0.68395  -9.66416  1.000 15.88134  ?  237 TYR A HE2  1 
ATOM   2414 N N    . LEU A 1 157 ? 30.46379  -5.36230  -5.61511  1.000 11.93874  ?  238 LEU A N    1 
ATOM   2415 C CA   . LEU A 1 157 ? 31.28542  -6.55187  -5.79812  1.000 12.59467  ?  238 LEU A CA   1 
ATOM   2416 C C    . LEU A 1 157 ? 31.10995  -7.50919  -4.62600  1.000 11.60721  ?  238 LEU A C    1 
ATOM   2417 O O    . LEU A 1 157 ? 30.95903  -8.70716  -4.83063  1.000 12.67035  ?  238 LEU A O    1 
ATOM   2418 C CB   . LEU A 1 157 ? 32.75194  -6.18267  -6.00560  1.000 14.36946  ?  238 LEU A CB   1 
ATOM   2419 C CG   . LEU A 1 157 ? 33.06975  -5.50001  -7.35556  1.000 17.87495  ?  238 LEU A CG   1 
ATOM   2420 C CD1  . LEU A 1 157 ? 34.48419  -4.92993  -7.27865  1.000 22.08317  ?  238 LEU A CD1  1 
ATOM   2421 C CD2  . LEU A 1 157 ? 32.90228  -6.41108  -8.53309  1.000 18.75579  ?  238 LEU A CD2  1 
ATOM   2422 H H    A LEU A 1 157 ? 30.99069  -4.49631  -5.50186  0.945 14.32648  ?  238 LEU A H    1 
ATOM   2423 D D    B LEU A 1 157 ? 30.99299  -4.49768  -5.50209  0.055 14.32648  ?  238 LEU A D    1 
ATOM   2424 H HA   . LEU A 1 157 ? 30.96707  -7.06332  -6.70651  1.000 15.11360  ?  238 LEU A HA   1 
ATOM   2425 H HB2  . LEU A 1 157 ? 33.04923  -5.49566  -5.21329  1.000 17.24335  ?  238 LEU A HB2  1 
ATOM   2426 H HB3  . LEU A 1 157 ? 33.34722  -7.09416  -5.95148  1.000 17.24335  ?  238 LEU A HB3  1 
ATOM   2427 H HG   . LEU A 1 157 ? 32.35370  -4.69661  -7.52858  1.000 21.44995  ?  238 LEU A HG   1 
ATOM   2428 H HD11 . LEU A 1 157 ? 35.17998  -5.73681  -7.04862  1.000 26.49980  ?  238 LEU A HD11 1 
ATOM   2429 H HD12 . LEU A 1 157 ? 34.73895  -4.48194  -8.23912  1.000 26.49980  ?  238 LEU A HD12 1 
ATOM   2430 H HD13 . LEU A 1 157 ? 34.51980  -4.17357  -6.49459  1.000 26.49980  ?  238 LEU A HD13 1 
ATOM   2431 H HD21 . LEU A 1 157 ? 33.00107  -7.44405  -8.19942  1.000 22.50694  ?  238 LEU A HD21 1 
ATOM   2432 H HD22 . LEU A 1 157 ? 31.91459  -6.25324  -8.96626  1.000 22.50694  ?  238 LEU A HD22 1 
ATOM   2433 H HD23 . LEU A 1 157 ? 33.67219  -6.18336  -9.27029  1.000 22.50694  ?  238 LEU A HD23 1 
ATOM   2434 N N    . ALA A 1 158 ? 31.09362  -6.99961  -3.39530  1.000 12.15192  ?  239 ALA A N    1 
ATOM   2435 C CA   . ALA A 1 158 ? 30.99399  -7.88415  -2.24715  1.000 11.69767  ?  239 ALA A CA   1 
ATOM   2436 C C    . ALA A 1 158 ? 29.63512  -8.53079  -2.17936  1.000 10.99881  ?  239 ALA A C    1 
ATOM   2437 O O    . ALA A 1 158 ? 29.51029  -9.69525  -1.82134  1.000 12.94985  ?  239 ALA A O    1 
ATOM   2438 C CB   . ALA A 1 158 ? 31.24168  -7.08989  -0.95990  1.000 14.28165  ?  239 ALA A CB   1 
ATOM   2439 H H    A ALA A 1 158 ? 31.14648  -6.00622  -3.16996  0.625 14.58230  ?  239 ALA A H    1 
ATOM   2440 D D    B ALA A 1 158 ? 31.14635  -6.00680  -3.16740  0.375 14.58230  ?  239 ALA A D    1 
ATOM   2441 H HA   . ALA A 1 158 ? 31.75206  -8.66211  -2.33769  1.000 14.03720  ?  239 ALA A HA   1 
ATOM   2442 H HB1  . ALA A 1 158 ? 31.49152  -7.78379  -0.15728  1.000 17.13798  ?  239 ALA A HB1  1 
ATOM   2443 H HB2  . ALA A 1 158 ? 32.06767  -6.39771  -1.12338  1.000 17.13798  ?  239 ALA A HB2  1 
ATOM   2444 H HB3  . ALA A 1 158 ? 30.33789  -6.53648  -0.70491  1.000 17.13798  ?  239 ALA A HB3  1 
ATOM   2445 N N    . CYS A 1 159 ? 28.57180  -7.78388  -2.48219  1.000 11.01259  ?  240 CYS A N    1 
ATOM   2446 C CA   . CYS A 1 159 ? 27.24283  -8.36466  -2.45487  1.000 11.14760  ?  240 CYS A CA   1 
ATOM   2447 C C    . CYS A 1 159 ? 27.03739  -9.40496  -3.55006  1.000 10.38155  ?  240 CYS A C    1 
ATOM   2448 O O    . CYS A 1 159 ? 26.45559  -10.46479 -3.30046  1.000 11.28489  ?  240 CYS A O    1 
ATOM   2449 C CB   . CYS A 1 159 ? 26.20823  -7.27221  -2.56559  1.000 11.68510  ?  240 CYS A CB   1 
ATOM   2450 S SG   . CYS A 1 159 ? 25.99064  -6.24044  -1.12309  1.000 14.87749  ?  240 CYS A SG   1 
ATOM   2451 H H    A CYS A 1 159 ? 28.60293  -6.79835  -2.74328  1.000 13.21510  ?  240 CYS A H    1 
ATOM   2452 D D    B CYS A 1 159 ? 28.60029  -6.79834  -2.74354  0.000 13.21510  ?  240 CYS A D    1 
ATOM   2453 H HA   . CYS A 1 159 ? 27.11578  -8.87478  -1.50002  1.000 13.37712  ?  240 CYS A HA   1 
ATOM   2454 H HB2  . CYS A 1 159 ? 26.49340  -6.61696  -3.38865  1.000 14.02212  ?  240 CYS A HB2  1 
ATOM   2455 H HB3  . CYS A 1 159 ? 25.24501  -7.73712  -2.77575  1.000 14.02212  ?  240 CYS A HB3  1 
ATOM   2456 N N    . VAL A 1 160 ? 27.50118  -9.13419  -4.78140  1.000 10.73939  ?  241 VAL A N    1 
ATOM   2457 C CA   . VAL A 1 160 ? 27.36927  -10.13142 -5.84148  1.000 11.51701  ?  241 VAL A CA   1 
ATOM   2458 C C    . VAL A 1 160 ? 28.15405  -11.38053 -5.44734  1.000 11.47290  ?  241 VAL A C    1 
ATOM   2459 O O    . VAL A 1 160 ? 27.70502  -12.50359 -5.64959  1.000 12.48260  ?  241 VAL A O    1 
ATOM   2460 C CB   . VAL A 1 160 ? 27.78088  -9.54207  -7.20974  1.000 10.64773  ?  241 VAL A CB   1 
ATOM   2461 C CG1  . VAL A 1 160 ? 27.96053  -10.64011 -8.22408  1.000 13.99436  ?  241 VAL A CG1  1 
ATOM   2462 C CG2  . VAL A 1 160 ? 26.74604  -8.52378  -7.65293  1.000 13.90847  ?  241 VAL A CG2  1 
ATOM   2463 H H    A VAL A 1 160 ? 27.95530  -8.26458  -5.06062  0.912 12.88727  ?  241 VAL A H    1 
ATOM   2464 D D    B VAL A 1 160 ? 27.95555  -8.26540  -5.06276  0.088 12.88727  ?  241 VAL A D    1 
ATOM   2465 H HA   . VAL A 1 160 ? 26.32380  -10.41900 -5.95282  1.000 13.82042  ?  241 VAL A HA   1 
ATOM   2466 H HB   . VAL A 1 160 ? 28.73992  -9.03123  -7.12387  1.000 12.77727  ?  241 VAL A HB   1 
ATOM   2467 H HG11 . VAL A 1 160 ? 28.93405  -10.52679 -8.70107  1.000 16.79324  ?  241 VAL A HG11 1 
ATOM   2468 H HG12 . VAL A 1 160 ? 27.90468  -11.60369 -7.71762  1.000 16.79324  ?  241 VAL A HG12 1 
ATOM   2469 H HG13 . VAL A 1 160 ? 27.16991  -10.56629 -8.97078  1.000 16.79324  ?  241 VAL A HG13 1 
ATOM   2470 H HG21 . VAL A 1 160 ? 26.07806  -8.31041  -6.81844  1.000 16.69017  ?  241 VAL A HG21 1 
ATOM   2471 H HG22 . VAL A 1 160 ? 27.25589  -7.61181  -7.96350  1.000 16.69017  ?  241 VAL A HG22 1 
ATOM   2472 H HG23 . VAL A 1 160 ? 26.17838  -8.93496  -8.48768  1.000 16.69017  ?  241 VAL A HG23 1 
ATOM   2473 N N    . ASN A 1 161 ? 29.36066  -11.20023 -4.89384  1.000 11.84409  ?  242 ASN A N    1 
ATOM   2474 C CA   . ASN A 1 161 ? 30.11992  -12.35078 -4.44633  1.000 10.61726  ?  242 ASN A CA   1 
ATOM   2475 C C    . ASN A 1 161 ? 29.36266  -13.15521 -3.40339  1.000 11.57914  ?  242 ASN A C    1 
ATOM   2476 O O    . ASN A 1 161 ? 29.37500  -14.39245 -3.44852  1.000 12.84195  ?  242 ASN A O    1 
ATOM   2477 C CB   . ASN A 1 161 ? 31.43271  -11.88742 -3.81664  1.000 12.10585  ?  242 ASN A CB   1 
ATOM   2478 C CG   . ASN A 1 161 ? 32.32718  -13.04786 -3.45530  1.000 15.71908  ?  242 ASN A CG   1 
ATOM   2479 O OD1  . ASN A 1 161 ? 32.76530  -13.79505 -4.33668  1.000 15.86917  ?  242 ASN A OD1  1 
ATOM   2480 N ND2  . ASN A 1 161 ? 32.60716  -13.20942 -2.17338  1.000 17.04873  ?  242 ASN A ND2  1 
ATOM   2481 H H    A ASN A 1 161 ? 29.81500  -10.29826 -4.75090  1.000 14.21291  ?  242 ASN A H    1 
ATOM   2482 D D    B ASN A 1 161 ? 29.81707  -10.29948 -4.74983  0.000 14.21291  ?  242 ASN A D    1 
ATOM   2483 H HA   . ASN A 1 161 ? 30.31590  -12.97848 -5.31563  1.000 12.74071  ?  242 ASN A HA   1 
ATOM   2484 H HB2  . ASN A 1 161 ? 31.96620  -11.25394 -4.52529  1.000 14.52702  ?  242 ASN A HB2  1 
ATOM   2485 H HB3  . ASN A 1 161 ? 31.21593  -11.32819 -2.90650  1.000 14.52702  ?  242 ASN A HB3  1 
ATOM   2486 N N    . TYR A 1 162 ? 28.71445  -12.47737 -2.44730  1.000 10.35265  ?  243 TYR A N    1 
ATOM   2487 C CA   . TYR A 1 162 ? 27.95260  -13.20226 -1.43060  1.000 10.53950  ?  243 TYR A CA   1 
ATOM   2488 C C    . TYR A 1 162 ? 26.83157  -14.01369 -2.05360  1.000 12.01579  ?  243 TYR A C    1 
ATOM   2489 O O    . TYR A 1 162 ? 26.60267  -15.17264 -1.68731  1.000 11.84545  ?  243 TYR A O    1 
ATOM   2490 C CB   . TYR A 1 162 ? 27.42440  -12.22618 -0.38690  1.000 11.74972  ?  243 TYR A CB   1 
ATOM   2491 C CG   . TYR A 1 162 ? 26.87596  -12.89837 0.81472   1.000 11.34316  ?  243 TYR A CG   1 
ATOM   2492 C CD1  . TYR A 1 162 ? 25.53517  -13.23355 0.92917   1.000 13.00089  ?  243 TYR A CD1  1 
ATOM   2493 C CD2  . TYR A 1 162 ? 27.70483  -13.20200 1.90966   1.000 13.22063  ?  243 TYR A CD2  1 
ATOM   2494 C CE1  . TYR A 1 162 ? 25.02853  -13.86019 2.04821   1.000 13.44209  ?  243 TYR A CE1  1 
ATOM   2495 C CE2  . TYR A 1 162 ? 27.20807  -13.82440 3.03713   1.000 13.64346  ?  243 TYR A CE2  1 
ATOM   2496 C CZ   . TYR A 1 162 ? 25.88382  -14.15312 3.09781   1.000 14.01489  ?  243 TYR A CZ   1 
ATOM   2497 O OH   . TYR A 1 162 ? 25.39113  -14.78810 4.24684   1.000 15.95291  ?  243 TYR A OH   1 
ATOM   2498 H H    A TYR A 1 162 ? 28.69911  -11.46172 -2.35437  1.000 12.42318  ?  243 TYR A H    1 
ATOM   2499 D D    B TYR A 1 162 ? 28.69757  -11.46195 -2.35223  0.000 12.42318  ?  243 TYR A D    1 
ATOM   2500 H HA   . TYR A 1 162 ? 28.61221  -13.90405 -0.92020  1.000 12.64740  ?  243 TYR A HA   1 
ATOM   2501 H HB2  . TYR A 1 162 ? 28.23932  -11.57734 -0.06593  1.000 14.09967  ?  243 TYR A HB2  1 
ATOM   2502 H HB3  . TYR A 1 162 ? 26.62702  -11.63090 -0.83178  1.000 14.09967  ?  243 TYR A HB3  1 
ATOM   2503 H HD1  . TYR A 1 162 ? 24.86600  -12.99607 0.11541   1.000 15.60107  ?  243 TYR A HD1  1 
ATOM   2504 H HD2  . TYR A 1 162 ? 28.75237  -12.94262 1.86740   1.000 15.86476  ?  243 TYR A HD2  1 
ATOM   2505 H HE1  . TYR A 1 162 ? 23.98144  -14.11852 2.10542   1.000 16.13050  ?  243 TYR A HE1  1 
ATOM   2506 H HE2  . TYR A 1 162 ? 27.86248  -14.05004 3.86613   1.000 16.37216  ?  243 TYR A HE2  1 
ATOM   2507 N N    . ALA A 1 163 ? 26.12222  -13.41654 -3.00720  1.000 11.35017  ?  244 ALA A N    1 
ATOM   2508 C CA   . ALA A 1 163 ? 25.05387  -14.12318 -3.69645  1.000 10.74861  ?  244 ALA A CA   1 
ATOM   2509 C C    . ALA A 1 163 ? 25.58657  -15.31927 -4.45028  1.000 11.32376  ?  244 ALA A C    1 
ATOM   2510 O O    . ALA A 1 163 ? 25.04480  -16.41793 -4.33328  1.000 12.13970  ?  244 ALA A O    1 
ATOM   2511 C CB   . ALA A 1 163 ? 24.31185  -13.13756 -4.60701  1.000 11.87984  ?  244 ALA A CB   1 
ATOM   2512 H H    A ALA A 1 163 ? 26.26202  -12.45604 -3.32072  1.000 13.62020  ?  244 ALA A H    1 
ATOM   2513 D D    B ALA A 1 163 ? 26.26024  -12.45630 -3.32230  0.000 13.62020  ?  244 ALA A D    1 
ATOM   2514 H HA   . ALA A 1 163 ? 24.33454  -14.51128 -2.97530  1.000 12.89834  ?  244 ALA A HA   1 
ATOM   2515 H HB1  . ALA A 1 163 ? 24.06903  -12.24114 -4.03641  1.000 14.25581  ?  244 ALA A HB1  1 
ATOM   2516 H HB2  . ALA A 1 163 ? 24.95430  -12.87960 -5.44891  1.000 14.25581  ?  244 ALA A HB2  1 
ATOM   2517 H HB3  . ALA A 1 163 ? 23.39702  -13.60761 -4.96790  1.000 14.25581  ?  244 ALA A HB3  1 
ATOM   2518 N N    . LEU A 1 164 ? 26.64520  -15.14441 -5.23764  1.000 9.79866   ?  245 LEU A N    1 
ATOM   2519 C CA   . LEU A 1 164 ? 27.13872  -16.26364 -6.04283  1.000 10.64866  ?  245 LEU A CA   1 
ATOM   2520 C C    . LEU A 1 164 ? 27.62077  -17.40530 -5.15759  1.000 11.15929  ?  245 LEU A C    1 
ATOM   2521 O O    . LEU A 1 164 ? 27.31306  -18.56547 -5.41595  1.000 12.69590  ?  245 LEU A O    1 
ATOM   2522 C CB   . LEU A 1 164 ? 28.28646  -15.79997 -6.94964  1.000 12.46378  ?  245 LEU A CB   1 
ATOM   2523 C CG   . LEU A 1 164 ? 27.96523  -14.75299 -8.00214  1.000 11.26618  ?  245 LEU A CG   1 
ATOM   2524 C CD1  . LEU A 1 164 ? 29.25696  -14.30905 -8.64907  1.000 14.90288  ?  245 LEU A CD1  1 
ATOM   2525 C CD2  . LEU A 1 164 ? 27.03729  -15.29034 -9.04574  1.000 15.59986  ?  245 LEU A CD2  1 
ATOM   2526 H H    A LEU A 1 164 ? 27.16666  -14.27368 -5.33920  0.928 11.75840  ?  245 LEU A H    1 
ATOM   2527 D D    B LEU A 1 164 ? 27.16808  -14.27472 -5.34072  0.072 11.75840  ?  245 LEU A D    1 
ATOM   2528 H HA   . LEU A 1 164 ? 26.32014  -16.62087 -6.66765  1.000 12.77839  ?  245 LEU A HA   1 
ATOM   2529 H HB2  . LEU A 1 164 ? 29.06564  -15.38003 -6.31353  1.000 14.95653  ?  245 LEU A HB2  1 
ATOM   2530 H HB3  . LEU A 1 164 ? 28.66759  -16.67345 -7.47867  1.000 14.95653  ?  245 LEU A HB3  1 
ATOM   2531 H HG   . LEU A 1 164 ? 27.46718  -13.90656 -7.52927  1.000 13.51941  ?  245 LEU A HG   1 
ATOM   2532 H HD11 . LEU A 1 164 ? 29.28548  -13.21970 -8.67362  1.000 17.88345  ?  245 LEU A HD11 1 
ATOM   2533 H HD12 . LEU A 1 164 ? 30.09524  -14.68976 -8.06558  1.000 17.88345  ?  245 LEU A HD12 1 
ATOM   2534 H HD13 . LEU A 1 164 ? 29.30008  -14.70496 -9.66370  1.000 17.88345  ?  245 LEU A HD13 1 
ATOM   2535 H HD21 . LEU A 1 164 ? 26.72269  -14.47357 -9.69537  1.000 18.71983  ?  245 LEU A HD21 1 
ATOM   2536 H HD22 . LEU A 1 164 ? 27.55986  -16.04875 -9.62870  1.000 18.71983  ?  245 LEU A HD22 1 
ATOM   2537 H HD23 . LEU A 1 164 ? 26.16910  -15.73102 -8.55569  1.000 18.71983  ?  245 LEU A HD23 1 
ATOM   2538 N N    . THR A 1 165 ? 28.39057  -17.08752 -4.11175  1.000 11.57117  ?  246 THR A N    1 
ATOM   2539 C CA   A THR A 1 165 ? 28.97718  -18.11856 -3.25462  0.609 11.76248  ?  246 THR A CA   1 
ATOM   2540 C CA   B THR A 1 165 ? 28.96450  -18.15713 -3.30670  0.391 11.59729  ?  246 THR A CA   1 
ATOM   2541 C C    . THR A 1 165 ? 27.88857  -18.88915 -2.52798  1.000 11.92299  ?  246 THR A C    1 
ATOM   2542 O O    . THR A 1 165 ? 27.96435  -20.09888 -2.37376  1.000 14.95614  ?  246 THR A O    1 
ATOM   2543 C CB   A THR A 1 165 ? 29.88309  -17.43661 -2.23127  0.609 11.54424  ?  246 THR A CB   1 
ATOM   2544 C CB   B THR A 1 165 ? 30.04903  -17.62641 -2.38558  0.391 14.78595  ?  246 THR A CB   1 
ATOM   2545 O OG1  A THR A 1 165 ? 30.99271  -16.81135 -2.90164  0.609 16.72027  ?  246 THR A OG1  1 
ATOM   2546 O OG1  B THR A 1 165 ? 29.51927  -16.58790 -1.57859  0.391 10.37690  ?  246 THR A OG1  1 
ATOM   2547 C CG2  A THR A 1 165 ? 30.45220  -18.43403 -1.21885  0.609 16.90477  ?  246 THR A CG2  1 
ATOM   2548 C CG2  B THR A 1 165 ? 31.23382  -17.12324 -3.21012  0.391 13.69336  ?  246 THR A CG2  1 
ATOM   2549 H H    A THR A 1 165 ? 28.62469  -16.13435 -3.83413  1.000 13.88540  ?  246 THR A H    1 
ATOM   2550 D D    B THR A 1 165 ? 28.62412  -16.14129 -3.81090  0.000 13.88540  ?  246 THR A D    1 
ATOM   2551 H HA   A THR A 1 165 ? 29.55963  -18.81601 -3.85663  0.609 14.11498  ?  246 THR A HA   1 
ATOM   2552 H HA   B THR A 1 165 ? 29.44430  -18.87307 -3.97403  0.391 13.91675  ?  246 THR A HA   1 
ATOM   2553 H HB   A THR A 1 165 ? 29.28670  -16.69794 -1.69575  0.609 13.85309  ?  246 THR A HB   1 
ATOM   2554 H HB   B THR A 1 165 ? 30.41232  -18.41799 -1.73020  0.391 17.74314  ?  246 THR A HB   1 
ATOM   2555 H HG1  A THR A 1 165 ? 31.47466  -17.47291 -3.44059  0.609 20.06433  ?  246 THR A HG1  1 
ATOM   2556 H HG1  B THR A 1 165 ? 28.57109  -16.45269 -1.78611  0.391 12.45228  ?  246 THR A HG1  1 
ATOM   2557 H HG21 A THR A 1 165 ? 31.21730  -19.04972 -1.69177  0.609 20.28573  ?  246 THR A HG21 1 
ATOM   2558 H HG21 B THR A 1 165 ? 30.97283  -16.18813 -3.70566  0.391 16.43203  ?  246 THR A HG21 1 
ATOM   2559 H HG22 A THR A 1 165 ? 30.89697  -17.90009 -0.37910  0.609 20.28573  ?  246 THR A HG22 1 
ATOM   2560 H HG22 B THR A 1 165 ? 32.09329  -16.95219 -2.56192  0.391 16.43203  ?  246 THR A HG22 1 
ATOM   2561 H HG23 A THR A 1 165 ? 29.65808  -19.08096 -0.84607  0.609 20.28573  ?  246 THR A HG23 1 
ATOM   2562 H HG23 B THR A 1 165 ? 31.50218  -17.86125 -3.96604  0.391 16.43203  ?  246 THR A HG23 1 
ATOM   2563 N N    . ASN A 1 166 ? 26.88117  -18.18607 -2.03487  1.000 11.78613  ?  247 ASN A N    1 
ATOM   2564 C CA   . ASN A 1 166 ? 25.87466  -18.84575 -1.20855  1.000 10.35080  ?  247 ASN A CA   1 
ATOM   2565 C C    . ASN A 1 166 ? 24.79392  -19.53975 -2.01649  1.000 12.94616  ?  247 ASN A C    1 
ATOM   2566 O O    . ASN A 1 166 ? 24.29687  -20.58439 -1.60988  1.000 14.05641  ?  247 ASN A O    1 
ATOM   2567 C CB   . ASN A 1 166 ? 25.30919  -17.84802 -0.18707  1.000 13.81890  ?  247 ASN A CB   1 
ATOM   2568 C CG   . ASN A 1 166 ? 26.22690  -17.66526 0.95782   1.000 16.58285  ?  247 ASN A CG   1 
ATOM   2569 O OD1  . ASN A 1 166 ? 26.28812  -18.49745 1.83791   1.000 23.20674  ?  247 ASN A OD1  1 
ATOM   2570 N ND2  . ASN A 1 166 ? 27.01738  -16.62388 0.93945   1.000 15.48326  ?  247 ASN A ND2  1 
ATOM   2571 H H    A ASN A 1 166 ? 26.73336  -17.18759 -2.18182  1.000 14.14336  ?  247 ASN A H    1 
ATOM   2572 D D    B ASN A 1 166 ? 26.73164  -17.18768 -2.18066  0.000 14.14336  ?  247 ASN A D    1 
ATOM   2573 H HA   . ASN A 1 166 ? 26.35490  -19.64512 -0.64423  1.000 12.42096  ?  247 ASN A HA   1 
ATOM   2574 H HB2  . ASN A 1 166 ? 25.16543  -16.88102 -0.66909  1.000 16.58268  ?  247 ASN A HB2  1 
ATOM   2575 H HB3  . ASN A 1 166 ? 24.35767  -18.22063 0.19222   1.000 16.58268  ?  247 ASN A HB3  1 
ATOM   2576 N N    . LEU A 1 167 ? 24.37629  -18.97265 -3.15222  1.000 11.55161  ?  248 LEU A N    1 
ATOM   2577 C CA   . LEU A 1 167 ? 23.42368  -19.68653 -4.00088  1.000 10.94859  ?  248 LEU A CA   1 
ATOM   2578 C C    . LEU A 1 167 ? 24.05879  -20.92465 -4.63002  1.000 12.65813  ?  248 LEU A C    1 
ATOM   2579 O O    . LEU A 1 167 ? 23.35227  -21.90622 -4.87841  1.000 12.30472  ?  248 LEU A O    1 
ATOM   2580 C CB   . LEU A 1 167 ? 22.84169  -18.73653 -5.03696  1.000 11.67496  ?  248 LEU A CB   1 
ATOM   2581 C CG   . LEU A 1 167 ? 21.93438  -17.68203 -4.45262  1.000 12.84289  ?  248 LEU A CG   1 
ATOM   2582 C CD1  . LEU A 1 167 ? 21.62923  -16.63600 -5.51606  1.000 19.23153  ?  248 LEU A CD1  1 
ATOM   2583 C CD2  . LEU A 1 167 ? 20.68391  -18.23092 -3.89630  1.000 17.82283  ?  248 LEU A CD2  1 
ATOM   2584 H H    A LEU A 1 167 ? 24.66719  -18.05803 -3.49753  1.000 13.86193  ?  248 LEU A H    1 
ATOM   2585 D D    B LEU A 1 167 ? 24.66569  -18.05833 -3.49958  0.000 13.86193  ?  248 LEU A D    1 
ATOM   2586 H HA   . LEU A 1 167 ? 22.58435  -20.04012 -3.40205  1.000 13.13830  ?  248 LEU A HA   1 
ATOM   2587 H HB2  . LEU A 1 167 ? 23.66131  -18.22754 -5.54416  1.000 14.00995  ?  248 LEU A HB2  1 
ATOM   2588 H HB3  . LEU A 1 167 ? 22.26101  -19.31546 -5.75513  1.000 14.00995  ?  248 LEU A HB3  1 
ATOM   2589 H HG   . LEU A 1 167 ? 22.45420  -17.22089 -3.61284  1.000 15.41147  ?  248 LEU A HG   1 
ATOM   2590 H HD11 . LEU A 1 167 ? 21.49178  -15.66856 -5.03308  1.000 23.07784  ?  248 LEU A HD11 1 
ATOM   2591 H HD12 . LEU A 1 167 ? 22.46382  -16.58704 -6.21546  1.000 23.07784  ?  248 LEU A HD12 1 
ATOM   2592 H HD13 . LEU A 1 167 ? 20.71874  -16.92098 -6.04320  1.000 23.07784  ?  248 LEU A HD13 1 
ATOM   2593 H HD21 . LEU A 1 167 ? 20.87932  -19.22707 -3.49929  1.000 21.38739  ?  248 LEU A HD21 1 
ATOM   2594 H HD22 . LEU A 1 167 ? 20.33230  -17.57559 -3.09943  1.000 21.38739  ?  248 LEU A HD22 1 
ATOM   2595 H HD23 . LEU A 1 167 ? 19.93733  -18.28639 -4.68853  1.000 21.38739  ?  248 LEU A HD23 1 
ATOM   2596 N N    . ALA A 1 168 ? 25.37567  -20.89730 -4.88822  1.000 11.25804  ?  249 ALA A N    1 
ATOM   2597 C CA   . ALA A 1 168 ? 26.02330  -22.09485 -5.40273  1.000 12.50743  ?  249 ALA A CA   1 
ATOM   2598 C C    . ALA A 1 168 ? 25.93855  -23.26820 -4.42319  1.000 13.47970  ?  249 ALA A C    1 
ATOM   2599 O O    . ALA A 1 168 ? 25.86858  -24.41716 -4.86139  1.000 13.68779  ?  249 ALA A O    1 
ATOM   2600 C CB   . ALA A 1 168 ? 27.48342  -21.79611 -5.72397  1.000 14.40456  ?  249 ALA A CB   1 
ATOM   2601 H H    A ALA A 1 168 ? 25.98797  -20.09251 -4.75479  0.964 13.50965  ?  249 ALA A H    1 
ATOM   2602 D D    B ALA A 1 168 ? 25.99000  -20.09391 -4.75565  0.036 13.50965  ?  249 ALA A D    1 
ATOM   2603 H HA   . ALA A 1 168 ? 25.51407  -22.38966 -6.32027  1.000 15.00891  ?  249 ALA A HA   1 
ATOM   2604 H HB1  . ALA A 1 168 ? 27.91190  -21.20722 -4.91297  1.000 17.28547  ?  249 ALA A HB1  1 
ATOM   2605 H HB2  . ALA A 1 168 ? 28.02406  -22.73708 -5.82590  1.000 17.28547  ?  249 ALA A HB2  1 
ATOM   2606 H HB3  . ALA A 1 168 ? 27.53390  -21.23543 -6.65734  1.000 17.28547  ?  249 ALA A HB3  1 
ATOM   2607 N N    . LYS A 1 169 ? 25.93172  -22.98737 -3.12007  1.000 13.09440  ?  250 LYS A N    1 
ATOM   2608 C CA   . LYS A 1 169 ? 25.86870  -24.05686 -2.13493  1.000 14.13288  ?  250 LYS A CA   1 
ATOM   2609 C C    . LYS A 1 169 ? 24.55833  -24.81043 -2.18148  1.000 15.12497  ?  250 LYS A C    1 
ATOM   2610 O O    . LYS A 1 169 ? 24.50773  -25.97126 -1.74239  1.000 18.09196  ?  250 LYS A O    1 
ATOM   2611 C CB   . LYS A 1 169 ? 26.07905  -23.49318 -0.72217  1.000 17.38282  ?  250 LYS A CB   1 
ATOM   2612 C CG   . LYS A 1 169 ? 27.51723  -22.96947 -0.52958  1.000 16.55557  ?  250 LYS A CG   1 
ATOM   2613 C CD   . LYS A 1 169 ? 27.65877  -22.32355 0.80738   1.000 20.21906  ?  250 LYS A CD   1 
ATOM   2614 C CE   . LYS A 1 169 ? 29.11317  -21.94325 1.05636   1.000 31.82609  ?  250 LYS A CE   1 
ATOM   2615 N NZ   . LYS A 1 169 ? 29.19485  -20.99033 2.20936   1.000 44.37357  ?  250 LYS A NZ   1 
ATOM   2616 H H    A LYS A 1 169 ? 25.96824  -22.04744 -2.72562  0.734 15.71328  ?  250 LYS A H    1 
ATOM   2617 D D    B LYS A 1 169 ? 25.96818  -22.04814 -2.72393  0.266 15.71328  ?  250 LYS A D    1 
ATOM   2618 H HA   . LYS A 1 169 ? 26.67407  -24.76030 -2.34625  1.000 16.95946  ?  250 LYS A HA   1 
ATOM   2619 H HB2  . LYS A 1 169 ? 25.38781  -22.66658 -0.55783  1.000 20.85939  ?  250 LYS A HB2  1 
ATOM   2620 H HB3  . LYS A 1 169 ? 25.89948  -24.28050 0.00993   1.000 20.85939  ?  250 LYS A HB3  1 
ATOM   2621 H HG2  . LYS A 1 169 ? 28.22053  -23.79994 -0.59116  1.000 19.86669  ?  250 LYS A HG2  1 
ATOM   2622 H HG3  . LYS A 1 169 ? 27.74399  -22.23110 -1.29866  1.000 19.86669  ?  250 LYS A HG3  1 
ATOM   2623 H HD2  . LYS A 1 169 ? 27.05074  -21.41964 0.84409   1.000 24.26288  ?  250 LYS A HD2  1 
ATOM   2624 H HD3  . LYS A 1 169 ? 27.34175  -23.01795 1.58546   1.000 24.26288  ?  250 LYS A HD3  1 
ATOM   2625 H HE2  . LYS A 1 169 ? 29.69166  -22.83540 1.29618   1.000 38.19131  ?  250 LYS A HE2  1 
ATOM   2626 H HE3  . LYS A 1 169 ? 29.52449  -21.45916 0.17060   1.000 38.19131  ?  250 LYS A HE3  1 
ATOM   2627 N N    . VAL A 1 170 ? 23.49454  -24.21071 -2.68334  1.000 13.22163  ?  251 VAL A N    1 
ATOM   2628 C CA   . VAL A 1 170 ? 22.21485  -24.88891 -2.81973  1.000 14.05840  ?  251 VAL A CA   1 
ATOM   2629 C C    . VAL A 1 170 ? 21.89604  -25.18610 -4.28318  1.000 12.29099  ?  251 VAL A C    1 
ATOM   2630 O O    . VAL A 1 170 ? 20.76240  -25.47259 -4.62003  1.000 16.25532  ?  251 VAL A O    1 
ATOM   2631 C CB   . VAL A 1 170 ? 21.05756  -24.15307 -2.11382  1.000 15.87222  ?  251 VAL A CB   1 
ATOM   2632 C CG1  . VAL A 1 170 ? 21.21596  -24.32826 -0.61428  1.000 20.03882  ?  251 VAL A CG1  1 
ATOM   2633 C CG2  . VAL A 1 170 ? 20.98471  -22.69592 -2.47779  1.000 15.99414  ?  251 VAL A CG2  1 
ATOM   2634 H H    A VAL A 1 170 ? 23.48480  -23.24409 -3.00884  0.553 15.86596  ?  251 VAL A H    1 
ATOM   2635 D D    B VAL A 1 170 ? 23.48634  -23.24395 -3.00845  0.447 15.86596  ?  251 VAL A D    1 
ATOM   2636 H HA   . VAL A 1 170 ? 22.31384  -25.84574 -2.30710  1.000 16.87007  ?  251 VAL A HA   1 
ATOM   2637 H HB   . VAL A 1 170 ? 20.11422  -24.58714 -2.44518  1.000 19.04667  ?  251 VAL A HB   1 
ATOM   2638 H HG11 . VAL A 1 170 ? 22.26010  -24.54730 -0.39092  1.000 24.04658  ?  251 VAL A HG11 1 
ATOM   2639 H HG12 . VAL A 1 170 ? 20.91449  -23.40711 -0.11558  1.000 24.04658  ?  251 VAL A HG12 1 
ATOM   2640 H HG13 . VAL A 1 170 ? 20.58437  -25.15323 -0.28471  1.000 24.04658  ?  251 VAL A HG13 1 
ATOM   2641 H HG21 . VAL A 1 170 ? 20.32248  -22.18775 -1.77686  1.000 19.19297  ?  251 VAL A HG21 1 
ATOM   2642 H HG22 . VAL A 1 170 ? 21.98481  -22.26595 -2.42266  1.000 19.19297  ?  251 VAL A HG22 1 
ATOM   2643 H HG23 . VAL A 1 170 ? 20.59528  -22.60241 -3.49155  1.000 19.19297  ?  251 VAL A HG23 1 
ATOM   2644 N N    . GLY A 1 171 ? 22.88163  -25.14014 -5.16386  1.000 11.78249  ?  252 GLY A N    1 
ATOM   2645 C CA   . GLY A 1 171 ? 22.72680  -25.71127 -6.48246  1.000 11.22712  ?  252 GLY A CA   1 
ATOM   2646 C C    . GLY A 1 171 ? 21.95336  -24.86858 -7.47693  1.000 10.99949  ?  252 GLY A C    1 
ATOM   2647 O O    . GLY A 1 171 ? 21.42795  -25.43257 -8.45360  1.000 12.67052  ?  252 GLY A O    1 
ATOM   2648 H H    A GLY A 1 171 ? 23.79338  -24.71607 -4.99273  0.708 14.13899  ?  252 GLY A H    1 
ATOM   2649 D D    B GLY A 1 171 ? 23.79371  -24.71636 -4.99382  0.292 14.13899  ?  252 GLY A D    1 
ATOM   2650 H HA2  . GLY A 1 171 ? 23.71770  -25.88663 -6.90134  1.000 13.47255  ?  252 GLY A HA2  1 
ATOM   2651 H HA3  . GLY A 1 171 ? 22.20803  -26.66513 -6.38689  1.000 13.47255  ?  252 GLY A HA3  1 
ATOM   2652 N N    . VAL A 1 172 ? 21.89454  -23.54078 -7.28228  1.000 10.23947  ?  253 VAL A N    1 
ATOM   2653 C CA   . VAL A 1 172 ? 21.22543  -22.63009 -8.21280  1.000 10.68405  ?  253 VAL A CA   1 
ATOM   2654 C C    . VAL A 1 172 ? 22.10180  -22.33791 -9.40727  1.000 10.45073  ?  253 VAL A C    1 
ATOM   2655 O O    . VAL A 1 172 ? 23.27333  -21.98645 -9.23607  1.000 12.01551  ?  253 VAL A O    1 
ATOM   2656 C CB   . VAL A 1 172 ? 20.88512  -21.33023 -7.47525  1.000 10.49774  ?  253 VAL A CB   1 
ATOM   2657 C CG1  . VAL A 1 172 ? 20.24780  -20.34604 -8.33657  1.000 13.40347  ?  253 VAL A CG1  1 
ATOM   2658 C CG2  . VAL A 1 172 ? 19.94860  -21.66080 -6.28599  1.000 12.99579  ?  253 VAL A CG2  1 
ATOM   2659 H H    A VAL A 1 172 ? 22.30677  -23.06555 -6.47939  0.862 12.28736  ?  253 VAL A H    1 
ATOM   2660 D D    B VAL A 1 172 ? 22.30674  -23.06549 -6.47942  0.138 12.28736  ?  253 VAL A D    1 
ATOM   2661 H HA   . VAL A 1 172 ? 20.32262  -23.11197 -8.58807  1.000 12.82086  ?  253 VAL A HA   1 
ATOM   2662 H HB   . VAL A 1 172 ? 21.81641  -20.88594 -7.12396  1.000 12.59729  ?  253 VAL A HB   1 
ATOM   2663 H HG11 . VAL A 1 172 ? 21.01085  -19.85793 -8.94286  1.000 16.08417  ?  253 VAL A HG11 1 
ATOM   2664 H HG12 . VAL A 1 172 ? 19.52815  -20.85123 -8.98076  1.000 16.08417  ?  253 VAL A HG12 1 
ATOM   2665 H HG13 . VAL A 1 172 ? 19.73803  -19.60877 -7.71634  1.000 16.08417  ?  253 VAL A HG13 1 
ATOM   2666 H HG21 . VAL A 1 172 ? 19.53488  -20.73273 -5.89150  1.000 15.59495  ?  253 VAL A HG21 1 
ATOM   2667 H HG22 . VAL A 1 172 ? 19.14393  -22.30691 -6.63691  1.000 15.59495  ?  253 VAL A HG22 1 
ATOM   2668 H HG23 . VAL A 1 172 ? 20.52352  -22.16988 -5.51243  1.000 15.59495  ?  253 VAL A HG23 1 
ATOM   2669 N N    . TYR A 1 173 ? 21.54367  -22.49061 -10.59957 1.000 9.68463   ?  254 TYR A N    1 
ATOM   2670 C CA   . TYR A 1 173 ? 22.23605  -22.10420 -11.81293 1.000 10.04377  ?  254 TYR A CA   1 
ATOM   2671 C C    . TYR A 1 173 ? 22.09005  -20.61533 -12.02781 1.000 10.31775  ?  254 TYR A C    1 
ATOM   2672 O O    . TYR A 1 173 ? 20.98828  -20.07847 -12.01109 1.000 13.09990  ?  254 TYR A O    1 
ATOM   2673 C CB   . TYR A 1 173 ? 21.65487  -22.88472 -13.01365 1.000 10.81520  ?  254 TYR A CB   1 
ATOM   2674 C CG   . TYR A 1 173 ? 22.12578  -24.30628 -12.99357 1.000 11.66177  ?  254 TYR A CG   1 
ATOM   2675 C CD1  . TYR A 1 173 ? 23.37940  -24.63734 -13.50376 1.000 13.35163  ?  254 TYR A CD1  1 
ATOM   2676 C CD2  . TYR A 1 173 ? 21.34595  -25.30884 -12.45053 1.000 13.01435  ?  254 TYR A CD2  1 
ATOM   2677 C CE1  . TYR A 1 173 ? 23.85049  -25.92954 -13.44586 1.000 15.64391  ?  254 TYR A CE1  1 
ATOM   2678 C CE2  . TYR A 1 173 ? 21.82997  -26.62734 -12.39447 1.000 15.50398  ?  254 TYR A CE2  1 
ATOM   2679 C CZ   . TYR A 1 173 ? 23.06078  -26.90659 -12.90349 1.000 17.23550  ?  254 TYR A CZ   1 
ATOM   2680 O OH   . TYR A 1 173 ? 23.53816  -28.19803 -12.86510 1.000 22.56617  ?  254 TYR A OH   1 
ATOM   2681 H H    A TYR A 1 173 ? 20.61351  -22.87905 -10.75550 1.000 11.62156  ?  254 TYR A H    1 
ATOM   2682 D D    B TYR A 1 173 ? 20.61356  -22.87901 -10.75587 0.000 11.62156  ?  254 TYR A D    1 
ATOM   2683 H HA   . TYR A 1 173 ? 23.29812  -22.33575 -11.73238 1.000 12.05253  ?  254 TYR A HA   1 
ATOM   2684 H HB2  . TYR A 1 173 ? 20.56621  -22.87798 -12.96010 1.000 12.97823  ?  254 TYR A HB2  1 
ATOM   2685 H HB3  . TYR A 1 173 ? 21.98526  -22.42178 -13.94350 1.000 12.97823  ?  254 TYR A HB3  1 
ATOM   2686 H HD1  . TYR A 1 173 ? 23.99107  -23.86814 -13.95164 1.000 16.02196  ?  254 TYR A HD1  1 
ATOM   2687 H HD2  . TYR A 1 173 ? 20.36233  -25.07917 -12.06825 1.000 15.61722  ?  254 TYR A HD2  1 
ATOM   2688 H HE1  . TYR A 1 173 ? 24.83302  -26.16964 -13.82453 1.000 18.77269  ?  254 TYR A HE1  1 
ATOM   2689 H HE2  . TYR A 1 173 ? 21.23162  -27.41019 -11.95229 1.000 18.60477  ?  254 TYR A HE2  1 
ATOM   2690 N N    . MET A 1 174 ? 23.19671  -19.93316 -12.23587 1.000 9.58904   ?  255 MET A N    1 
ATOM   2691 C CA   . MET A 1 174 ? 23.23669  -18.45949 -12.19179 1.000 9.24497   ?  255 MET A CA   1 
ATOM   2692 C C    . MET A 1 174 ? 23.78795  -17.88434 -13.47908 1.000 10.35865  ?  255 MET A C    1 
ATOM   2693 O O    . MET A 1 174 ? 24.81837  -18.37254 -13.99058 1.000 11.44958  ?  255 MET A O    1 
ATOM   2694 C CB   . MET A 1 174 ? 24.09582  -17.94792 -11.03094 1.000 10.32720  ?  255 MET A CB   1 
ATOM   2695 C CG   . MET A 1 174 ? 23.51254  -18.31807 -9.72012  1.000 11.11669  ?  255 MET A CG   1 
ATOM   2696 S SD   . MET A 1 174 ? 24.55213  -18.09582 -8.29765  1.000 14.80684  ?  255 MET A SD   1 
ATOM   2697 C CE   . MET A 1 174 ? 25.52350  -19.56624 -8.29700  1.000 13.75245  ?  255 MET A CE   1 
ATOM   2698 H H    A MET A 1 174 ? 24.09925  -20.36199 -12.44064 1.000 11.50685  ?  255 MET A H    1 
ATOM   2699 D D    B MET A 1 174 ? 24.09829  -20.36405 -12.44051 0.000 11.50685  ?  255 MET A D    1 
ATOM   2700 H HA   . MET A 1 174 ? 22.21098  -18.11625 -12.05685 1.000 11.09397  ?  255 MET A HA   1 
ATOM   2701 H HB2  . MET A 1 174 ? 25.09175  -18.38551 -11.09974 1.000 12.39264  ?  255 MET A HB2  1 
ATOM   2702 H HB3  . MET A 1 174 ? 24.16168  -16.86117 -11.08316 1.000 12.39264  ?  255 MET A HB3  1 
ATOM   2703 H HG2  . MET A 1 174 ? 22.62173  -17.71015 -9.56204  1.000 13.34003  ?  255 MET A HG2  1 
ATOM   2704 H HG3  . MET A 1 174 ? 23.24219  -19.37342 -9.75562  1.000 13.34003  ?  255 MET A HG3  1 
ATOM   2705 H HE1  . MET A 1 174 ? 25.70456  -19.87148 -7.26639  1.000 16.50293  ?  255 MET A HE1  1 
ATOM   2706 H HE2  . MET A 1 174 ? 24.98177  -20.34966 -8.82698  1.000 16.50293  ?  255 MET A HE2  1 
ATOM   2707 H HE3  . MET A 1 174 ? 26.47098  -19.36585 -8.79722  1.000 16.50293  ?  255 MET A HE3  1 
ATOM   2708 N N    . TYR A 1 175 ? 23.16922  -16.79318 -13.93389 1.000 9.31680   ?  256 TYR A N    1 
ATOM   2709 C CA   . TYR A 1 175 ? 23.63574  -15.99047 -15.04821 1.000 8.22080   ?  256 TYR A CA   1 
ATOM   2710 C C    . TYR A 1 175 ? 23.73613  -14.56840 -14.52325 1.000 10.08708  ?  256 TYR A C    1 
ATOM   2711 O O    . TYR A 1 175 ? 22.73806  -13.97179 -14.11373 1.000 11.20473  ?  256 TYR A O    1 
ATOM   2712 C CB   . TYR A 1 175 ? 22.71862  -16.06949 -16.24035 1.000 9.09579   ?  256 TYR A CB   1 
ATOM   2713 C CG   . TYR A 1 175 ? 22.61647  -17.44801 -16.81045 1.000 9.78928   ?  256 TYR A CG   1 
ATOM   2714 C CD1  . TYR A 1 175 ? 21.72156  -18.39391 -16.26373 1.000 10.44784  ?  256 TYR A CD1  1 
ATOM   2715 C CD2  . TYR A 1 175 ? 23.40720  -17.84570 -17.90986 1.000 10.96591  ?  256 TYR A CD2  1 
ATOM   2716 C CE1  . TYR A 1 175 ? 21.64907  -19.66565 -16.79880 1.000 11.34851  ?  256 TYR A CE1  1 
ATOM   2717 C CE2  . TYR A 1 175 ? 23.31331  -19.10045 -18.43106 1.000 10.43562  ?  256 TYR A CE2  1 
ATOM   2718 C CZ   . TYR A 1 175 ? 22.43924  -20.02831 -17.86373 1.000 12.01428  ?  256 TYR A CZ   1 
ATOM   2719 O OH   . TYR A 1 175 ? 22.29616  -21.30305 -18.41085 1.000 13.05500  ?  256 TYR A OH   1 
ATOM   2720 H H    A TYR A 1 175 ? 22.30618  -16.43179 -13.52775 0.922 11.18017  ?  256 TYR A H    1 
ATOM   2721 D D    B TYR A 1 175 ? 22.30618  -16.43333 -13.52637 0.078 11.18017  ?  256 TYR A D    1 
ATOM   2722 H HA   . TYR A 1 175 ? 24.60996  -16.33787 -15.39219 1.000 9.86496   ?  256 TYR A HA   1 
ATOM   2723 H HB2  . TYR A 1 175 ? 21.71927  -15.75563 -15.93889 1.000 10.91495  ?  256 TYR A HB2  1 
ATOM   2724 H HB3  . TYR A 1 175 ? 23.09673  -15.40998 -17.02149 1.000 10.91495  ?  256 TYR A HB3  1 
ATOM   2725 H HD1  . TYR A 1 175 ? 21.09397  -18.12321 -15.42752 1.000 12.53741  ?  256 TYR A HD1  1 
ATOM   2726 H HD2  . TYR A 1 175 ? 24.10004  -17.14145 -18.34620 1.000 13.15910  ?  256 TYR A HD2  1 
ATOM   2727 H HE1  . TYR A 1 175 ? 20.96292  -20.38401 -16.37505 1.000 13.61821  ?  256 TYR A HE1  1 
ATOM   2728 H HE2  . TYR A 1 175 ? 23.91558  -19.37732 -19.28371 1.000 12.52274  ?  256 TYR A HE2  1 
ATOM   2729 N N    . MET A 1 176 ? 24.91969  -13.99534 -14.52950 1.000 9.87805   ?  257 MET A N    1 
ATOM   2730 C CA   . MET A 1 176 ? 25.10997  -12.62553 -14.09706 1.000 11.20145  ?  257 MET A CA   1 
ATOM   2731 C C    . MET A 1 176 ? 24.67496  -11.68909 -15.20087 1.000 9.25899   ?  257 MET A C    1 
ATOM   2732 O O    . MET A 1 176 ? 24.96857  -11.89530 -16.37175 1.000 10.45027  ?  257 MET A O    1 
ATOM   2733 C CB   . MET A 1 176 ? 26.59539  -12.37966 -13.78416 1.000 13.37490  ?  257 MET A CB   1 
ATOM   2734 C CG   . MET A 1 176 ? 27.03374  -13.04769 -12.54265 1.000 15.33889  ?  257 MET A CG   1 
ATOM   2735 S SD   . MET A 1 176 ? 28.71261  -12.51789 -12.10793 1.000 19.47427  ?  257 MET A SD   1 
ATOM   2736 C CE   . MET A 1 176 ? 29.65703  -13.29151 -13.38740 1.000 23.79973  ?  257 MET A CE   1 
ATOM   2737 H H    A MET A 1 176 ? 25.77857  -14.45544 -14.83121 0.868 11.85366  ?  257 MET A H    1 
ATOM   2738 D D    B MET A 1 176 ? 25.77884  -14.45500 -14.83111 0.132 11.85366  ?  257 MET A D    1 
ATOM   2739 H HA   . MET A 1 176 ? 24.52984  -12.43608 -13.19391 1.000 13.44175  ?  257 MET A HA   1 
ATOM   2740 H HB2  . MET A 1 176 ? 27.19965  -12.76372 -14.60603 1.000 16.04988  ?  257 MET A HB2  1 
ATOM   2741 H HB3  . MET A 1 176 ? 26.76127  -11.30861 -13.66828 1.000 16.04988  ?  257 MET A HB3  1 
ATOM   2742 H HG2  . MET A 1 176 ? 26.36134  -12.78246 -11.72679 1.000 18.40667  ?  257 MET A HG2  1 
ATOM   2743 H HG3  . MET A 1 176 ? 27.03495  -14.12788 -12.68857 1.000 18.40667  ?  257 MET A HG3  1 
ATOM   2744 H HE1  . MET A 1 176 ? 29.74669  -12.60326 -14.22786 1.000 28.55968  ?  257 MET A HE1  1 
ATOM   2745 H HE2  . MET A 1 176 ? 30.64610  -13.53598 -13.00001 1.000 28.55968  ?  257 MET A HE2  1 
ATOM   2746 H HE3  . MET A 1 176 ? 29.14682  -14.20102 -13.70456 1.000 28.55968  ?  257 MET A HE3  1 
ATOM   2747 N N    . ASP A 1 177 ? 23.99218  -10.60859 -14.82667 1.000 10.91995  ?  258 ASP A N    1 
ATOM   2748 C CA   . ASP A 1 177 ? 23.60121  -9.63004  -15.83542 1.000 10.17094  ?  258 ASP A CA   1 
ATOM   2749 C C    . ASP A 1 177 ? 24.84758  -9.02126  -16.47278 1.000 11.37974  ?  258 ASP A C    1 
ATOM   2750 O O    . ASP A 1 177 ? 25.79383  -8.63922  -15.79073 1.000 12.21681  ?  258 ASP A O    1 
ATOM   2751 C CB   . ASP A 1 177 ? 22.79703  -8.50330  -15.21370 1.000 9.75552   ?  258 ASP A CB   1 
ATOM   2752 C CG   . ASP A 1 177 ? 22.32923  -7.52529  -16.24510 1.000 11.29836  ?  258 ASP A CG   1 
ATOM   2753 O OD1  . ASP A 1 177 ? 21.27778  -7.77373  -16.85699 1.000 14.11655  ?  258 ASP A OD1  1 
ATOM   2754 O OD2  . ASP A 1 177 ? 23.02697  -6.55146  -16.52145 1.000 12.81425  -1 258 ASP A OD2  1 
ATOM   2755 H H    A ASP A 1 177 ? 23.70647  -10.39131 -13.87192 0.907 13.10393  ?  258 ASP A H    1 
ATOM   2756 D D    B ASP A 1 177 ? 23.70569  -10.38979 -13.87250 0.093 13.10393  ?  258 ASP A D    1 
ATOM   2757 H HA   . ASP A 1 177 ? 22.99043  -10.12895 -16.58784 1.000 12.20513  ?  258 ASP A HA   1 
ATOM   2758 H HB2  . ASP A 1 177 ? 21.92194  -8.91869  -14.71393 1.000 11.70663  ?  258 ASP A HB2  1 
ATOM   2759 H HB3  . ASP A 1 177 ? 23.41946  -7.97097  -14.49447 1.000 11.70663  ?  258 ASP A HB3  1 
ATOM   2760 N N    . ALA A 1 178 ? 24.79214  -8.82569  -17.79503 1.000 9.73926   ?  259 ALA A N    1 
ATOM   2761 C CA   . ALA A 1 178 ? 25.90642  -8.29646  -18.58076 1.000 10.28641  ?  259 ALA A CA   1 
ATOM   2762 C C    . ALA A 1 178 ? 25.41630  -7.22739  -19.55344 1.000 10.41339  ?  259 ALA A C    1 
ATOM   2763 O O    . ALA A 1 178 ? 25.92824  -7.06402  -20.66839 1.000 11.15217  ?  259 ALA A O    1 
ATOM   2764 C CB   . ALA A 1 178 ? 26.68600  -9.37199  -19.31766 1.000 10.80321  ?  259 ALA A CB   1 
ATOM   2765 H H    A ALA A 1 178 ? 23.96751  -9.03059  -18.35929 0.907 11.68711  ?  259 ALA A H    1 
ATOM   2766 D D    B ALA A 1 178 ? 23.96621  -9.03141  -18.35709 0.093 11.68711  ?  259 ALA A D    1 
ATOM   2767 H HA   . ALA A 1 178 ? 26.60051  -7.83869  -17.87592 1.000 12.34369  ?  259 ALA A HA   1 
ATOM   2768 H HB1  . ALA A 1 178 ? 26.01609  -9.88704  -20.00617 1.000 12.96385  ?  259 ALA A HB1  1 
ATOM   2769 H HB2  . ALA A 1 178 ? 27.49992  -8.90391  -19.87132 1.000 12.96385  ?  259 ALA A HB2  1 
ATOM   2770 H HB3  . ALA A 1 178 ? 27.08835  -10.07879 -18.59196 1.000 12.96385  ?  259 ALA A HB3  1 
ATOM   2771 N N    . GLY A 1 179 ? 24.42880  -6.42854  -19.15604 1.000 9.65107   ?  260 GLY A N    1 
ATOM   2772 C CA   . GLY A 1 179 ? 24.01490  -5.33085  -20.01640 1.000 10.95354  ?  260 GLY A CA   1 
ATOM   2773 C C    . GLY A 1 179 ? 23.51808  -5.83209  -21.35949 1.000 11.22581  ?  260 GLY A C    1 
ATOM   2774 O O    . GLY A 1 179 ? 22.83383  -6.83815  -21.47179 1.000 10.69628  ?  260 GLY A O    1 
ATOM   2775 H H    A GLY A 1 179 ? 23.91619  -6.51271  -18.27823 0.540 11.58128  ?  260 GLY A H    1 
ATOM   2776 D D    B GLY A 1 179 ? 23.91453  -6.51031  -18.27898 0.460 11.58128  ?  260 GLY A D    1 
ATOM   2777 H HA2  . GLY A 1 179 ? 23.21144  -4.77323  -19.53515 1.000 13.14425  ?  260 GLY A HA2  1 
ATOM   2778 H HA3  . GLY A 1 179 ? 24.85883  -4.66218  -20.18598 1.000 13.14425  ?  260 GLY A HA3  1 
ATOM   2779 N N    . HIS A 1 180 ? 23.84524  -5.10035  -22.42138 1.000 10.32473  ?  261 HIS A N    1 
ATOM   2780 C CA   . HIS A 1 180 ? 23.36930  -5.41110  -23.76353 1.000 10.44366  ?  261 HIS A CA   1 
ATOM   2781 C C    . HIS A 1 180 ? 24.37340  -4.87179  -24.77522 1.000 10.86116  ?  261 HIS A C    1 
ATOM   2782 O O    . HIS A 1 180 ? 25.36537  -4.25133  -24.42730 1.000 10.62037  ?  261 HIS A O    1 
ATOM   2783 C CB   . HIS A 1 180 ? 21.95635  -4.88195  -23.99361 1.000 11.27577  ?  261 HIS A CB   1 
ATOM   2784 C CG   . HIS A 1 180 ? 21.82511  -3.40494  -23.90690 1.000 12.17412  ?  261 HIS A CG   1 
ATOM   2785 N ND1  . HIS A 1 180 ? 22.03384  -2.59009  -25.01290 1.000 12.46989  ?  261 HIS A ND1  1 
ATOM   2786 C CD2  . HIS A 1 180 ? 21.49124  -2.58545  -22.87576 1.000 15.47546  ?  261 HIS A CD2  1 
ATOM   2787 C CE1  . HIS A 1 180 ? 21.84443  -1.32457  -24.64835 1.000 13.50495  ?  261 HIS A CE1  1 
ATOM   2788 N NE2  . HIS A 1 180 ? 21.52339  -1.29571  -23.36110 1.000 15.33679  ?  261 HIS A NE2  1 
ATOM   2789 H H    A HIS A 1 180 ? 24.44553  -4.27663  -22.38230 0.664 12.38967  ?  261 HIS A H    1 
ATOM   2790 D D    B HIS A 1 180 ? 24.44561  -4.27672  -22.38154 0.336 12.38967  ?  261 HIS A D    1 
ATOM   2791 H HA   . HIS A 1 180 ? 23.33080  -6.49366  -23.88474 1.000 12.53239  ?  261 HIS A HA   1 
ATOM   2792 H HB2  . HIS A 1 180 ? 21.63194  -5.18232  -24.98992 1.000 13.53093  ?  261 HIS A HB2  1 
ATOM   2793 H HB3  . HIS A 1 180 ? 21.29753  -5.31472  -23.24077 1.000 13.53093  ?  261 HIS A HB3  1 
ATOM   2794 H HD2  . HIS A 1 180 ? 21.24717  -2.88715  -21.86789 1.000 18.57056  ?  261 HIS A HD2  1 
ATOM   2795 H HE1  . HIS A 1 180 ? 21.93670  -0.46330  -25.29340 1.000 16.20595  ?  261 HIS A HE1  1 
ATOM   2796 N N    . ALA A 1 181 ? 24.10877  -5.13327  -26.05891 1.000 10.78689  ?  262 ALA A N    1 
ATOM   2797 C CA   . ALA A 1 181 ? 25.07470  -4.79873  -27.11985 1.000 9.85515   ?  262 ALA A CA   1 
ATOM   2798 C C    . ALA A 1 181 ? 25.40972  -3.32103  -27.14348 1.000 11.61871  ?  262 ALA A C    1 
ATOM   2799 O O    . ALA A 1 181 ? 26.55662  -2.95551  -27.43568 1.000 13.70702  ?  262 ALA A O    1 
ATOM   2800 C CB   . ALA A 1 181 ? 24.49587  -5.23617  -28.45397 1.000 12.11039  ?  262 ALA A CB   1 
ATOM   2801 H H    A ALA A 1 181 ? 23.25067  -5.56864  -26.39732 0.631 12.94427  ?  262 ALA A H    1 
ATOM   2802 D D    B ALA A 1 181 ? 23.25160  -5.56848  -26.39987 0.369 12.94427  ?  262 ALA A D    1 
ATOM   2803 H HA   . ALA A 1 181 ? 26.00868  -5.33205  -26.94274 1.000 11.82618  ?  262 ALA A HA   1 
ATOM   2804 H HB1  . ALA A 1 181 ? 25.03241  -4.73020  -29.25661 1.000 14.53247  ?  262 ALA A HB1  1 
ATOM   2805 H HB2  . ALA A 1 181 ? 24.60988  -6.31562  -28.55345 1.000 14.53247  ?  262 ALA A HB2  1 
ATOM   2806 H HB3  . ALA A 1 181 ? 23.43956  -4.96935  -28.48711 1.000 14.53247  ?  262 ALA A HB3  1 
ATOM   2807 N N    . GLY A 1 182 ? 24.43728  -2.46220  -26.79162 1.000 10.52040  ?  263 GLY A N    1 
ATOM   2808 C CA   . GLY A 1 182 ? 24.64700  -1.04355  -26.81540 1.000 12.21114  ?  263 GLY A CA   1 
ATOM   2809 C C    . GLY A 1 182 ? 25.24745  -0.46347  -25.56114 1.000 13.67268  ?  263 GLY A C    1 
ATOM   2810 O O    . GLY A 1 182 ? 25.47882  0.73724   -25.47728 1.000 14.46198  ?  263 GLY A O    1 
ATOM   2811 H H    A GLY A 1 182 ? 23.50391  -2.74165  -26.48975 0.806 12.62448  ?  263 GLY A H    1 
ATOM   2812 D D    B GLY A 1 182 ? 23.50408  -2.74229  -26.48982 0.194 12.62448  ?  263 GLY A D    1 
ATOM   2813 H HA2  . GLY A 1 182 ? 25.31474  -0.80486  -27.64319 1.000 14.65337  ?  263 GLY A HA2  1 
ATOM   2814 H HA3  . GLY A 1 182 ? 23.68763  -0.55322  -26.98062 1.000 14.65337  ?  263 GLY A HA3  1 
ATOM   2815 N N    . TRP A 1 183 ? 25.58579  -1.31872  -24.59727 1.000 12.57093  ?  264 TRP A N    1 
ATOM   2816 C CA   . TRP A 1 183 ? 26.23311  -0.90548  -23.35466 1.000 11.16396  ?  264 TRP A CA   1 
ATOM   2817 C C    . TRP A 1 183 ? 27.63264  -1.48900  -23.35217 1.000 12.63290  ?  264 TRP A C    1 
ATOM   2818 O O    . TRP A 1 183 ? 28.60686  -0.75865  -23.48977 1.000 14.30320  ?  264 TRP A O    1 
ATOM   2819 C CB   . TRP A 1 183 ? 25.39914  -1.39092  -22.17495 1.000 12.24250  ?  264 TRP A CB   1 
ATOM   2820 C CG   . TRP A 1 183 ? 25.82927  -0.83230  -20.84892 1.000 12.09427  ?  264 TRP A CG   1 
ATOM   2821 C CD1  . TRP A 1 183 ? 26.97654  -0.12567  -20.57207 1.000 13.83664  ?  264 TRP A CD1  1 
ATOM   2822 C CD2  . TRP A 1 183 ? 25.09737  -0.88581  -19.61614 1.000 12.36051  ?  264 TRP A CD2  1 
ATOM   2823 N NE1  . TRP A 1 183 ? 26.97706  0.26916   -19.25438 1.000 14.23384  ?  264 TRP A NE1  1 
ATOM   2824 C CE2  . TRP A 1 183 ? 25.84994  -0.18361  -18.64664 1.000 13.24565  ?  264 TRP A CE2  1 
ATOM   2825 C CE3  . TRP A 1 183 ? 23.89916  -1.43518  -19.25245 1.000 13.48962  ?  264 TRP A CE3  1 
ATOM   2826 C CZ2  . TRP A 1 183 ? 25.41468  -0.02430  -17.32255 1.000 16.34418  ?  264 TRP A CZ2  1 
ATOM   2827 C CZ3  . TRP A 1 183 ? 23.46664  -1.27378  -17.90841 1.000 15.71077  ?  264 TRP A CZ3  1 
ATOM   2828 C CH2  . TRP A 1 183 ? 24.24237  -0.60042  -16.98853 1.000 14.39345  ?  264 TRP A CH2  1 
ATOM   2829 H H    A TRP A 1 183 ? 25.42085  -2.32393  -24.64978 1.000 15.08511  ?  264 TRP A H    1 
ATOM   2830 D D    B TRP A 1 183 ? 25.42028  -2.32377  -24.65105 0.000 15.08511  ?  264 TRP A D    1 
ATOM   2831 H HA   . TRP A 1 183 ? 26.30808  0.17863   -23.26992 1.000 13.39676  ?  264 TRP A HA   1 
ATOM   2832 H HB2  . TRP A 1 183 ? 24.36180  -1.09792  -22.33676 1.000 14.69100  ?  264 TRP A HB2  1 
ATOM   2833 H HB3  . TRP A 1 183 ? 25.47515  -2.47672  -22.11705 1.000 14.69100  ?  264 TRP A HB3  1 
ATOM   2834 H HD1  . TRP A 1 183 ? 27.76052  0.08750   -21.28364 1.000 16.60396  ?  264 TRP A HD1  1 
ATOM   2835 H HE3  . TRP A 1 183 ? 23.29774  -1.97709  -19.96730 1.000 16.18755  ?  264 TRP A HE3  1 
ATOM   2836 H HZ2  . TRP A 1 183 ? 25.99323  0.53523   -16.60241 1.000 19.61302  ?  264 TRP A HZ2  1 
ATOM   2837 H HZ3  . TRP A 1 183 ? 22.51583  -1.68482  -17.60279 1.000 18.85293  ?  264 TRP A HZ3  1 
ATOM   2838 H HH2  . TRP A 1 183 ? 23.89954  -0.53224  -15.96666 1.000 17.27215  ?  264 TRP A HH2  1 
ATOM   2839 N N    . LEU A 1 184 ? 27.76393  -2.79420  -23.20024 1.000 12.78690  ?  265 LEU A N    1 
ATOM   2840 C CA   . LEU A 1 184 ? 29.05676  -3.45910  -23.11292 1.000 11.50077  ?  265 LEU A CA   1 
ATOM   2841 C C    . LEU A 1 184 ? 29.53878  -4.02996  -24.43180 1.000 12.14540  ?  265 LEU A C    1 
ATOM   2842 O O    . LEU A 1 184 ? 30.70214  -4.44251  -24.52083 1.000 14.70946  ?  265 LEU A O    1 
ATOM   2843 C CB   . LEU A 1 184 ? 29.00503  -4.56110  -22.06443 1.000 13.37758  ?  265 LEU A CB   1 
ATOM   2844 C CG   . LEU A 1 184 ? 28.65699  -4.04218  -20.65338 1.000 12.69390  ?  265 LEU A CG   1 
ATOM   2845 C CD1  . LEU A 1 184 ? 28.80709  -5.21344  -19.66715 1.000 15.00929  ?  265 LEU A CD1  1 
ATOM   2846 C CD2  . LEU A 1 184 ? 29.52618  -2.89898  -20.20790 1.000 17.29026  ?  265 LEU A CD2  1 
ATOM   2847 H H    A LEU A 1 184 ? 26.97564  -3.43792  -23.13223 0.776 15.34428  ?  265 LEU A H    1 
ATOM   2848 D D    B LEU A 1 184 ? 26.97497  -3.43710  -23.13233 0.224 15.34428  ?  265 LEU A D    1 
ATOM   2849 H HA   . LEU A 1 184 ? 29.79986  -2.72846  -22.79343 1.000 13.80093  ?  265 LEU A HA   1 
ATOM   2850 H HB2  . LEU A 1 184 ? 28.24409  -5.28620  -22.35304 1.000 16.05309  ?  265 LEU A HB2  1 
ATOM   2851 H HB3  . LEU A 1 184 ? 29.98056  -5.04470  -22.01355 1.000 16.05309  ?  265 LEU A HB3  1 
ATOM   2852 H HG   . LEU A 1 184 ? 27.63720  -3.65763  -20.66875 1.000 15.23268  ?  265 LEU A HG   1 
ATOM   2853 H HD11 . LEU A 1 184 ? 28.41029  -4.91370  -18.69720 1.000 18.01115  ?  265 LEU A HD11 1 
ATOM   2854 H HD12 . LEU A 1 184 ? 28.25154  -6.07077  -20.04720 1.000 18.01115  ?  265 LEU A HD12 1 
ATOM   2855 H HD13 . LEU A 1 184 ? 29.86330  -5.46631  -19.57462 1.000 18.01115  ?  265 LEU A HD13 1 
ATOM   2856 H HD21 . LEU A 1 184 ? 29.00623  -2.34012  -19.42980 1.000 20.74831  ?  265 LEU A HD21 1 
ATOM   2857 H HD22 . LEU A 1 184 ? 30.46280  -3.29663  -19.81711 1.000 20.74831  ?  265 LEU A HD22 1 
ATOM   2858 H HD23 . LEU A 1 184 ? 29.72491  -2.25075  -21.06137 1.000 20.74831  ?  265 LEU A HD23 1 
ATOM   2859 N N    . GLY A 1 185 ? 28.70013  -4.01574  -25.48460 1.000 12.33739  ?  266 GLY A N    1 
ATOM   2860 C CA   . GLY A 1 185 ? 29.08735  -4.60663  -26.75253 1.000 13.52377  ?  266 GLY A CA   1 
ATOM   2861 C C    . GLY A 1 185 ? 29.94449  -3.71723  -27.61560 1.000 13.07793  ?  266 GLY A C    1 
ATOM   2862 O O    . GLY A 1 185 ? 30.52587  -4.20157  -28.59231 1.000 15.56421  ?  266 GLY A O    1 
ATOM   2863 H H    A GLY A 1 185 ? 27.76570  -3.60684  -25.47777 0.955 14.80487  ?  266 GLY A H    1 
ATOM   2864 D D    B GLY A 1 185 ? 27.76550  -3.60729  -25.47941 0.045 14.80487  ?  266 GLY A D    1 
ATOM   2865 H HA2  . GLY A 1 185 ? 29.64519  -5.52259  -26.55776 1.000 16.22853  ?  266 GLY A HA2  1 
ATOM   2866 H HA3  . GLY A 1 185 ? 28.18689  -4.85244  -27.31543 1.000 16.22853  ?  266 GLY A HA3  1 
ATOM   2867 N N    . TRP A 1 186 ? 30.01554  -2.42796  -27.31118 1.000 13.72459  ?  267 TRP A N    1 
ATOM   2868 C CA   . TRP A 1 186 ? 30.98272  -1.55358  -27.98214 1.000 13.81276  ?  267 TRP A CA   1 
ATOM   2869 C C    . TRP A 1 186 ? 32.35693  -2.22588  -27.92598 1.000 12.97333  ?  267 TRP A C    1 
ATOM   2870 O O    . TRP A 1 186 ? 32.77730  -2.65726  -26.85390 1.000 14.49646  ?  267 TRP A O    1 
ATOM   2871 C CB   . TRP A 1 186 ? 31.03026  -0.18103  -27.30536 1.000 13.48529  ?  267 TRP A CB   1 
ATOM   2872 C CG   . TRP A 1 186 ? 29.79708  0.60008   -27.54445 1.000 14.43465  ?  267 TRP A CG   1 
ATOM   2873 C CD1  . TRP A 1 186 ? 28.67602  0.65904   -26.76630 1.000 13.33197  ?  267 TRP A CD1  1 
ATOM   2874 C CD2  . TRP A 1 186 ? 29.54221  1.44909   -28.65465 1.000 13.10339  ?  267 TRP A CD2  1 
ATOM   2875 N NE1  . TRP A 1 186 ? 27.71763  1.45452   -27.34913 1.000 15.06439  ?  267 TRP A NE1  1 
ATOM   2876 C CE2  . TRP A 1 186 ? 28.24047  1.97344   -28.50761 1.000 14.67555  ?  267 TRP A CE2  1 
ATOM   2877 C CE3  . TRP A 1 186 ? 30.30828  1.82826   -29.76789 1.000 14.34678  ?  267 TRP A CE3  1 
ATOM   2878 C CZ2  . TRP A 1 186 ? 27.67610  2.84543   -29.43727 1.000 18.18778  ?  267 TRP A CZ2  1 
ATOM   2879 C CZ3  . TRP A 1 186 ? 29.75791  2.71665   -30.68683 1.000 17.35650  ?  267 TRP A CZ3  1 
ATOM   2880 C CH2  . TRP A 1 186 ? 28.44595  3.21418   -30.51991 1.000 16.94839  ?  267 TRP A CH2  1 
ATOM   2881 H H    A TRP A 1 186 ? 29.43117  -1.96031  -26.61821 0.995 16.46951  ?  267 TRP A H    1 
ATOM   2882 D D    B TRP A 1 186 ? 29.43193  -1.95890  -26.61853 0.005 16.46951  ?  267 TRP A D    1 
ATOM   2883 H HA   . TRP A 1 186 ? 30.69561  -1.39163  -29.02111 1.000 16.57532  ?  267 TRP A HA   1 
ATOM   2884 H HB2  . TRP A 1 186 ? 31.14460  -0.31623  -26.22984 1.000 16.18235  ?  267 TRP A HB2  1 
ATOM   2885 H HB3  . TRP A 1 186 ? 31.87369  0.38429   -27.70178 1.000 16.18235  ?  267 TRP A HB3  1 
ATOM   2886 H HD1  . TRP A 1 186 ? 28.55827  0.14981   -25.82120 1.000 15.99836  ?  267 TRP A HD1  1 
ATOM   2887 H HE3  . TRP A 1 186 ? 31.30549  1.43816   -29.90860 1.000 17.21614  ?  267 TRP A HE3  1 
ATOM   2888 H HZ2  . TRP A 1 186 ? 26.67043  3.21926   -29.31371 1.000 21.82534  ?  267 TRP A HZ2  1 
ATOM   2889 H HZ3  . TRP A 1 186 ? 30.34176  3.03026   -31.53958 1.000 20.82780  ?  267 TRP A HZ3  1 
ATOM   2890 H HH2  . TRP A 1 186 ? 28.03926  3.89503   -31.25303 1.000 20.33806  ?  267 TRP A HH2  1 
ATOM   2891 N N    . PRO A 1 187 ? 33.08966  -2.32172  -29.04793 1.000 14.32991  ?  268 PRO A N    1 
ATOM   2892 C CA   . PRO A 1 187 ? 34.37276  -3.04299  -29.01714 1.000 14.30322  ?  268 PRO A CA   1 
ATOM   2893 C C    . PRO A 1 187 ? 35.31658  -2.60755  -27.92190 1.000 14.57868  ?  268 PRO A C    1 
ATOM   2894 O O    . PRO A 1 187 ? 36.00258  -3.43546  -27.33331 1.000 18.10695  ?  268 PRO A O    1 
ATOM   2895 C CB   . PRO A 1 187 ? 34.94214  -2.80437  -30.42119 1.000 18.24581  ?  268 PRO A CB   1 
ATOM   2896 C CG   . PRO A 1 187 ? 33.68601  -2.75552  -31.29909 1.000 21.33468  ?  268 PRO A CG   1 
ATOM   2897 C CD   . PRO A 1 187 ? 32.63557  -2.03864  -30.42559 1.000 15.67788  ?  268 PRO A CD   1 
ATOM   2898 H HA   . PRO A 1 187 ? 34.17902  -4.10802  -28.88955 1.000 17.16387  ?  268 PRO A HA   1 
ATOM   2899 H HB2  . PRO A 1 187 ? 35.48827  -1.86165  -30.45466 1.000 21.89497  ?  268 PRO A HB2  1 
ATOM   2900 H HB3  . PRO A 1 187 ? 35.59807  -3.62564  -30.70993 1.000 21.89497  ?  268 PRO A HB3  1 
ATOM   2901 H HG2  . PRO A 1 187 ? 33.88797  -2.19283  -32.21051 1.000 25.60162  ?  268 PRO A HG2  1 
ATOM   2902 H HG3  . PRO A 1 187 ? 33.36426  -3.76658  -31.54874 1.000 25.60162  ?  268 PRO A HG3  1 
ATOM   2903 H HD2  . PRO A 1 187 ? 32.63473  -0.96635  -30.62126 1.000 18.81345  ?  268 PRO A HD2  1 
ATOM   2904 H HD3  . PRO A 1 187 ? 31.64109  -2.44996  -30.59859 1.000 18.81345  ?  268 PRO A HD3  1 
ATOM   2905 N N    . ALA A 1 188 ? 35.34456  -1.31625  -27.59256 1.000 15.41999  ?  269 ALA A N    1 
ATOM   2906 C CA   . ALA A 1 188 ? 36.25693  -0.83652  -26.57054 1.000 13.44914  ?  269 ALA A CA   1 
ATOM   2907 C C    . ALA A 1 188 ? 35.86897  -1.26435  -25.16360 1.000 14.14370  ?  269 ALA A C    1 
ATOM   2908 O O    . ALA A 1 188 ? 36.69232  -1.19850  -24.25524 1.000 16.72627  ?  269 ALA A O    1 
ATOM   2909 C CB   . ALA A 1 188 ? 36.28368  0.68844   -26.62881 1.000 18.86895  ?  269 ALA A CB   1 
ATOM   2910 H H    A ALA A 1 188 ? 34.75687  -0.59482  -28.01035 0.558 18.50399  ?  269 ALA A H    1 
ATOM   2911 D D    B ALA A 1 188 ? 34.75765  -0.59356  -28.00928 0.442 18.50399  ?  269 ALA A D    1 
ATOM   2912 H HA   . ALA A 1 188 ? 37.24858  -1.24242  -26.77050 1.000 16.13896  ?  269 ALA A HA   1 
ATOM   2913 H HB1  . ALA A 1 188 ? 35.42273  1.03692   -27.19928 1.000 22.64274  ?  269 ALA A HB1  1 
ATOM   2914 H HB2  . ALA A 1 188 ? 36.24140  1.08315   -25.61367 1.000 22.64274  ?  269 ALA A HB2  1 
ATOM   2915 H HB3  . ALA A 1 188 ? 37.20556  1.00890   -27.11414 1.000 22.64274  ?  269 ALA A HB3  1 
ATOM   2916 N N    . ASN A 1 189 ? 34.61799  -1.70103  -24.94840 1.000 14.10993  ?  270 ASN A N    1 
ATOM   2917 C CA   . ASN A 1 189 ? 34.14974  -2.09738  -23.62830 1.000 14.09441  ?  270 ASN A CA   1 
ATOM   2918 C C    . ASN A 1 189 ? 34.25216  -3.60128  -23.39604 1.000 15.19144  ?  270 ASN A C    1 
ATOM   2919 O O    . ASN A 1 189 ? 34.08596  -4.04082  -22.25742 1.000 14.21203  ?  270 ASN A O    1 
ATOM   2920 C CB   . ASN A 1 189 ? 32.69560  -1.66355  -23.45778 1.000 13.16443  ?  270 ASN A CB   1 
ATOM   2921 C CG   . ASN A 1 189 ? 32.52324  -0.15889  -23.38972 1.000 15.13452  ?  270 ASN A CG   1 
ATOM   2922 O OD1  . ASN A 1 189 ? 33.49264  0.56697   -23.15523 1.000 17.85894  ?  270 ASN A OD1  1 
ATOM   2923 N ND2  . ASN A 1 189 ? 31.31791  0.32845   -23.57532 1.000 15.32804  ?  270 ASN A ND2  1 
ATOM   2924 H H    A ASN A 1 189 ? 33.91049  -1.78805  -25.67797 0.596 16.93191  ?  270 ASN A H    1 
ATOM   2925 D D    B ASN A 1 189 ? 33.91118  -1.78770  -25.67868 0.404 16.93191  ?  270 ASN A D    1 
ATOM   2926 H HA   . ASN A 1 189 ? 34.74975  -1.59968  -22.86647 1.000 16.91329  ?  270 ASN A HA   1 
ATOM   2927 H HB2  . ASN A 1 189 ? 32.11660  -2.02857  -24.30608 1.000 15.79732  ?  270 ASN A HB2  1 
ATOM   2928 H HB3  . ASN A 1 189 ? 32.30727  -2.08699  -22.53150 1.000 15.79732  ?  270 ASN A HB3  1 
ATOM   2929 N N    . LEU A 1 190 ? 34.54123  -4.38403  -24.44628 1.000 14.27709  ?  271 LEU A N    1 
ATOM   2930 C CA   . LEU A 1 190 ? 34.49982  -5.83452  -24.30650 1.000 13.09563  ?  271 LEU A CA   1 
ATOM   2931 C C    . LEU A 1 190 ? 35.58988  -6.33269  -23.36083 1.000 14.93128  ?  271 LEU A C    1 
ATOM   2932 O O    . LEU A 1 190 ? 35.33278  -7.15245  -22.48684 1.000 15.89503  ?  271 LEU A O    1 
ATOM   2933 C CB   . LEU A 1 190 ? 34.64127  -6.45917  -25.68743 1.000 15.13916  ?  271 LEU A CB   1 
ATOM   2934 C CG   . LEU A 1 190 ? 33.52869  -6.28833  -26.67723 1.000 16.46304  ?  271 LEU A CG   1 
ATOM   2935 C CD1  . LEU A 1 190 ? 33.98551  -6.74474  -28.02060 1.000 18.25202  ?  271 LEU A CD1  1 
ATOM   2936 C CD2  . LEU A 1 190 ? 32.34719  -7.10262  -26.22185 1.000 17.19917  ?  271 LEU A CD2  1 
ATOM   2937 H H    A LEU A 1 190 ? 34.79868  -4.04892  -25.37462 0.690 17.13250  ?  271 LEU A H    1 
ATOM   2938 D D    B LEU A 1 190 ? 34.79888  -4.05114  -25.37536 0.310 17.13250  ?  271 LEU A D    1 
ATOM   2939 H HA   . LEU A 1 190 ? 33.54359  -6.13763  -23.88006 1.000 15.71475  ?  271 LEU A HA   1 
ATOM   2940 H HB2  . LEU A 1 190 ? 35.53265  -6.03408  -26.14877 1.000 18.16699  ?  271 LEU A HB2  1 
ATOM   2941 H HB3  . LEU A 1 190 ? 34.76901  -7.53278  -25.54906 1.000 18.16699  ?  271 LEU A HB3  1 
ATOM   2942 H HG   . LEU A 1 190 ? 33.23339  -5.24172  -26.75150 1.000 19.75565  ?  271 LEU A HG   1 
ATOM   2943 H HD11 . LEU A 1 190 ? 33.99935  -7.83449  -28.03940 1.000 21.90242  ?  271 LEU A HD11 1 
ATOM   2944 H HD12 . LEU A 1 190 ? 33.29613  -6.36868  -28.77654 1.000 21.90242  ?  271 LEU A HD12 1 
ATOM   2945 H HD13 . LEU A 1 190 ? 34.98733  -6.35704  -28.20539 1.000 21.90242  ?  271 LEU A HD13 1 
ATOM   2946 H HD21 . LEU A 1 190 ? 32.65830  -8.13966  -26.09587 1.000 20.63901  ?  271 LEU A HD21 1 
ATOM   2947 H HD22 . LEU A 1 190 ? 31.98652  -6.70490  -25.27325 1.000 20.63901  ?  271 LEU A HD22 1 
ATOM   2948 H HD23 . LEU A 1 190 ? 31.56122  -7.03915  -26.97440 1.000 20.63901  ?  271 LEU A HD23 1 
ATOM   2949 N N    . SER A 1 191 ? 36.82110  -5.85392  -23.51328 1.000 15.39765  ?  272 SER A N    1 
ATOM   2950 C CA   . SER A 1 191 ? 37.91821  -6.36884  -22.70028 1.000 16.93226  ?  272 SER A CA   1 
ATOM   2951 C C    . SER A 1 191 ? 37.75990  -5.95976  -21.24763 1.000 17.87751  ?  272 SER A C    1 
ATOM   2952 O O    . SER A 1 191 ? 37.86641  -6.83329  -20.36561 1.000 17.17151  ?  272 SER A O    1 
ATOM   2953 C CB   . SER A 1 191 ? 39.25425  -5.94814  -23.32433 1.000 25.83466  ?  272 SER A CB   1 
ATOM   2954 O OG   . SER A 1 191 ? 40.34344  -6.33548  -22.50154 1.000 39.72227  ?  272 SER A OG   1 
ATOM   2955 H H    A SER A 1 191 ? 37.08839  -5.12565  -24.17553 0.686 18.47718  ?  272 SER A H    1 
ATOM   2956 D D    B SER A 1 191 ? 37.09186  -5.12588  -24.17438 0.314 18.47718  ?  272 SER A D    1 
ATOM   2957 H HA   . SER A 1 191 ? 37.90362  -7.45861  -22.71755 1.000 20.31871  ?  272 SER A HA   1 
ATOM   2958 H HB2  . SER A 1 191 ? 39.35733  -6.42800  -24.29758 1.000 31.00160  ?  272 SER A HB2  1 
ATOM   2959 H HB3  . SER A 1 191 ? 39.26554  -4.86435  -23.43997 1.000 31.00160  ?  272 SER A HB3  1 
ATOM   2960 N N    . PRO A 1 192 ? 37.49095  -4.69285  -20.91929 1.000 18.21915  ?  273 PRO A N    1 
ATOM   2961 C CA   . PRO A 1 192 ? 37.19344  -4.35637  -19.52700 1.000 16.76918  ?  273 PRO A CA   1 
ATOM   2962 C C    . PRO A 1 192 ? 36.06261  -5.18680  -18.93062 1.000 15.00500  ?  273 PRO A C    1 
ATOM   2963 O O    . PRO A 1 192 ? 36.13186  -5.59293  -17.76446 1.000 15.97014  ?  273 PRO A O    1 
ATOM   2964 C CB   . PRO A 1 192 ? 36.84244  -2.87184  -19.58408 1.000 16.81682  ?  273 PRO A CB   1 
ATOM   2965 C CG   . PRO A 1 192 ? 37.47565  -2.37591  -20.80642 1.000 25.70665  ?  273 PRO A CG   1 
ATOM   2966 C CD   . PRO A 1 192 ? 37.49431  -3.50296  -21.80174 1.000 18.84357  ?  273 PRO A CD   1 
ATOM   2967 H HA   . PRO A 1 192 ? 38.09234  -4.48278  -18.92358 1.000 20.12301  ?  273 PRO A HA   1 
ATOM   2968 H HB2  . PRO A 1 192 ? 35.76033  -2.74864  -19.62844 1.000 20.18018  ?  273 PRO A HB2  1 
ATOM   2969 H HB3  . PRO A 1 192 ? 37.23985  -2.36334  -18.70568 1.000 20.18018  ?  273 PRO A HB3  1 
ATOM   2970 H HG2  . PRO A 1 192 ? 36.89796  -1.53734  -21.19524 1.000 30.84798  ?  273 PRO A HG2  1 
ATOM   2971 H HG3  . PRO A 1 192 ? 38.49224  -2.05486  -20.57932 1.000 30.84798  ?  273 PRO A HG3  1 
ATOM   2972 H HD2  . PRO A 1 192 ? 36.60881  -3.48166  -22.43698 1.000 22.61229  ?  273 PRO A HD2  1 
ATOM   2973 H HD3  . PRO A 1 192 ? 38.39440  -3.47090  -22.41568 1.000 22.61229  ?  273 PRO A HD3  1 
ATOM   2974 N N    . ALA A 1 193 ? 35.01570  -5.44361  -19.71452 1.000 14.85094  ?  274 ALA A N    1 
ATOM   2975 C CA   . ALA A 1 193 ? 33.88761  -6.24555  -19.21429 1.000 13.12952  ?  274 ALA A CA   1 
ATOM   2976 C C    . ALA A 1 193 ? 34.32846  -7.67983  -18.94356 1.000 13.31641  ?  274 ALA A C    1 
ATOM   2977 O O    . ALA A 1 193 ? 34.05568  -8.23645  -17.87113 1.000 13.72414  ?  274 ALA A O    1 
ATOM   2978 C CB   . ALA A 1 193 ? 32.73459  -6.22326  -20.21709 1.000 12.76690  ?  274 ALA A CB   1 
ATOM   2979 H H    A ALA A 1 193 ? 34.91440  -5.12212  -20.67721 1.000 17.82112  ?  274 ALA A H    1 
ATOM   2980 D D    B ALA A 1 193 ? 34.91229  -5.12320  -20.67735 0.000 17.82112  ?  274 ALA A D    1 
ATOM   2981 H HA   . ALA A 1 193 ? 33.52943  -5.80757  -18.28263 1.000 15.75542  ?  274 ALA A HA   1 
ATOM   2982 H HB1  . ALA A 1 193 ? 31.79252  -6.31651  -19.67680 1.000 15.32027  ?  274 ALA A HB1  1 
ATOM   2983 H HB2  . ALA A 1 193 ? 32.75784  -5.28050  -20.76370 1.000 15.32027  ?  274 ALA A HB2  1 
ATOM   2984 H HB3  . ALA A 1 193 ? 32.85018  -7.05723  -20.90936 1.000 15.32027  ?  274 ALA A HB3  1 
ATOM   2985 N N    . ALA A 1 194 ? 35.07631  -8.28777  -19.88308 1.000 13.92697  ?  275 ALA A N    1 
ATOM   2986 C CA   . ALA A 1 194 ? 35.55997  -9.66705  -19.69337 1.000 13.77049  ?  275 ALA A CA   1 
ATOM   2987 C C    . ALA A 1 194 ? 36.43698  -9.74980  -18.46803 1.000 14.26019  ?  275 ALA A C    1 
ATOM   2988 O O    . ALA A 1 194 ? 36.35214  -10.71247 -17.69664 1.000 16.84659  ?  275 ALA A O    1 
ATOM   2989 C CB   . ALA A 1 194 ? 36.31071  -10.14199 -20.92432 1.000 13.90725  ?  275 ALA A CB   1 
ATOM   2990 H H    A ALA A 1 194 ? 35.35813  -7.86243  -20.76629 1.000 16.71237  ?  275 ALA A H    1 
ATOM   2991 D D    B ALA A 1 194 ? 35.35944  -7.86470  -20.76696 0.000 16.71237  ?  275 ALA A D    1 
ATOM   2992 H HA   . ALA A 1 194 ? 34.70598  -10.33089 -19.55873 1.000 16.52459  ?  275 ALA A HA   1 
ATOM   2993 H HB1  . ALA A 1 194 ? 35.62960  -10.14731 -21.77530 1.000 16.68870  ?  275 ALA A HB1  1 
ATOM   2994 H HB2  . ALA A 1 194 ? 37.14134  -9.46309  -21.11730 1.000 16.68870  ?  275 ALA A HB2  1 
ATOM   2995 H HB3  . ALA A 1 194 ? 36.68768  -11.14864 -20.74365 1.000 16.68870  ?  275 ALA A HB3  1 
ATOM   2996 N N    . GLN A 1 195 ? 37.27806  -8.74618  -18.25424 1.000 15.21740  ?  276 GLN A N    1 
ATOM   2997 C CA   . GLN A 1 195 ? 38.15590  -8.75315  -17.09375 1.000 17.22370  ?  276 GLN A CA   1 
ATOM   2998 C C    . GLN A 1 195 ? 37.32287  -8.71360  -15.80874 1.000 18.06840  ?  276 GLN A C    1 
ATOM   2999 O O    . GLN A 1 195 ? 37.62493  -9.42381  -14.84195 1.000 18.94646  ?  276 GLN A O    1 
ATOM   3000 C CB   . GLN A 1 195 ? 39.09415  -7.55824  -17.13028 1.000 17.81038  ?  276 GLN A CB   1 
ATOM   3001 C CG   . GLN A 1 195 ? 40.20151  -7.66467  -18.18463 1.000 43.31068  ?  276 GLN A CG   1 
ATOM   3002 C CD   . GLN A 1 195 ? 41.06681  -6.40041  -18.21065 1.000 69.41707  ?  276 GLN A CD   1 
ATOM   3003 O OE1  . GLN A 1 195 ? 41.73388  -6.06946  -17.22347 1.000 51.41089  ?  276 GLN A OE1  1 
ATOM   3004 N NE2  . GLN A 1 195 ? 41.03613  -5.67427  -19.33705 1.000 42.59867  ?  276 GLN A NE2  1 
ATOM   3005 H H    A GLN A 1 195 ? 37.37493  -7.92738  -18.85472 0.494 18.26088  ?  276 GLN A H    1 
ATOM   3006 D D    B GLN A 1 195 ? 37.37683  -7.92641  -18.85309 0.506 18.26088  ?  276 GLN A D    1 
ATOM   3007 H HA   . GLN A 1 195 ? 38.76254  -9.65857  -17.11112 1.000 20.66844  ?  276 GLN A HA   1 
ATOM   3008 H HB2  . GLN A 1 195 ? 38.51162  -6.66376  -17.35087 1.000 21.37246  ?  276 GLN A HB2  1 
ATOM   3009 H HB3  . GLN A 1 195 ? 39.57283  -7.46049  -16.15590 1.000 21.37246  ?  276 GLN A HB3  1 
ATOM   3010 H HG2  . GLN A 1 195 ? 40.84197  -8.51540  -17.95191 1.000 51.97282  ?  276 GLN A HG2  1 
ATOM   3011 H HG3  . GLN A 1 195 ? 39.75222  -7.79459  -19.16919 1.000 51.97282  ?  276 GLN A HG3  1 
ATOM   3012 N N    . LEU A 1 196 ? 36.29529  -7.84470  -15.75813 1.000 14.08695  ?  277 LEU A N    1 
ATOM   3013 C CA   . LEU A 1 196 ? 35.48724  -7.71763  -14.55039 1.000 14.80455  ?  277 LEU A CA   1 
ATOM   3014 C C    . LEU A 1 196 ? 34.72839  -9.01072  -14.25991 1.000 13.22308  ?  277 LEU A C    1 
ATOM   3015 O O    . LEU A 1 196 ? 34.78772  -9.53698  -13.14044 1.000 13.73048  ?  277 LEU A O    1 
ATOM   3016 C CB   . LEU A 1 196 ? 34.50483  -6.57077  -14.71399 1.000 14.16726  ?  277 LEU A CB   1 
ATOM   3017 C CG   . LEU A 1 196 ? 33.55766  -6.42613  -13.53319 1.000 17.39551  ?  277 LEU A CG   1 
ATOM   3018 C CD1  . LEU A 1 196 ? 34.22744  -6.19367  -12.21004 1.000 24.24284  ?  277 LEU A CD1  1 
ATOM   3019 C CD2  . LEU A 1 196 ? 32.57818  -5.27593  -13.80698 1.000 28.15457  ?  277 LEU A CD2  1 
ATOM   3020 H H    A LEU A 1 196 ? 36.01101  -7.23321  -16.52341 0.909 16.90434  ?  277 LEU A H    1 
ATOM   3021 D D    B LEU A 1 196 ? 36.00926  -7.23233  -16.52206 0.091 16.90434  ?  277 LEU A D    1 
ATOM   3022 H HA   . LEU A 1 196 ? 36.14464  -7.50420  -13.70756 1.000 17.76545  ?  277 LEU A HA   1 
ATOM   3023 H HB2  . LEU A 1 196 ? 35.06278  -5.63980  -14.81447 1.000 17.00071  ?  277 LEU A HB2  1 
ATOM   3024 H HB3  . LEU A 1 196 ? 33.90534  -6.74442  -15.60761 1.000 17.00071  ?  277 LEU A HB3  1 
ATOM   3025 H HG   . LEU A 1 196 ? 33.04067  -7.38090  -13.43711 1.000 20.87461  ?  277 LEU A HG   1 
ATOM   3026 H HD11 . LEU A 1 196 ? 35.30039  -6.34879  -12.32332 1.000 29.09141  ?  277 LEU A HD11 1 
ATOM   3027 H HD12 . LEU A 1 196 ? 34.03169  -5.17088  -11.88804 1.000 29.09141  ?  277 LEU A HD12 1 
ATOM   3028 H HD13 . LEU A 1 196 ? 33.82526  -6.89648  -11.48038 1.000 29.09141  ?  277 LEU A HD13 1 
ATOM   3029 H HD21 . LEU A 1 196 ? 31.59765  -5.54348  -13.41319 1.000 33.78548  ?  277 LEU A HD21 1 
ATOM   3030 H HD22 . LEU A 1 196 ? 32.94303  -4.37439  -13.31483 1.000 33.78548  ?  277 LEU A HD22 1 
ATOM   3031 H HD23 . LEU A 1 196 ? 32.51470  -5.11236  -14.88276 1.000 33.78548  ?  277 LEU A HD23 1 
ATOM   3032 N N    . PHE A 1 197 ? 34.06891  -9.57213  -15.26897 1.000 12.32541  ?  278 PHE A N    1 
ATOM   3033 C CA   . PHE A 1 197 ? 33.24828  -10.74106 -15.00779 1.000 12.82599  ?  278 PHE A CA   1 
ATOM   3034 C C    . PHE A 1 197 ? 34.11009  -11.93809 -14.63946 1.000 14.49709  ?  278 PHE A C    1 
ATOM   3035 O O    . PHE A 1 197 ? 33.72797  -12.75128 -13.78727 1.000 14.48623  ?  278 PHE A O    1 
ATOM   3036 C CB   . PHE A 1 197 ? 32.35657  -11.05598 -16.22628 1.000 16.43904  ?  278 PHE A CB   1 
ATOM   3037 C CG   . PHE A 1 197 ? 31.27722  -10.04278 -16.44181 1.000 15.87385  ?  278 PHE A CG   1 
ATOM   3038 C CD1  . PHE A 1 197 ? 30.35683  -9.77528  -15.43656 1.000 20.07695  ?  278 PHE A CD1  1 
ATOM   3039 C CD2  . PHE A 1 197 ? 31.19582  -9.36858  -17.64374 1.000 20.85739  ?  278 PHE A CD2  1 
ATOM   3040 C CE1  . PHE A 1 197 ? 29.35993  -8.81987  -15.62559 1.000 25.84756  ?  278 PHE A CE1  1 
ATOM   3041 C CE2  . PHE A 1 197 ? 30.20996  -8.41921  -17.82594 1.000 22.79910  ?  278 PHE A CE2  1 
ATOM   3042 C CZ   . PHE A 1 197 ? 29.30804  -8.14442  -16.81078 1.000 20.95530  ?  278 PHE A CZ   1 
ATOM   3043 H H    A PHE A 1 197 ? 34.08328  -9.25273  -16.23757 0.889 14.79049  ?  278 PHE A H    1 
ATOM   3044 D D    B PHE A 1 197 ? 34.08168  -9.25465  -16.23822 0.111 14.79049  ?  278 PHE A D    1 
ATOM   3045 H HA   . PHE A 1 197 ? 32.58737  -10.52815 -14.16757 1.000 15.39119  ?  278 PHE A HA   1 
ATOM   3046 H HB2  . PHE A 1 197 ? 32.97771  -11.08046 -17.12165 1.000 19.72685  ?  278 PHE A HB2  1 
ATOM   3047 H HB3  . PHE A 1 197 ? 31.88172  -12.02543 -16.07536 1.000 19.72685  ?  278 PHE A HB3  1 
ATOM   3048 H HD1  . PHE A 1 197 ? 30.41415  -10.31188 -14.50105 1.000 24.09234  ?  278 PHE A HD1  1 
ATOM   3049 H HD2  . PHE A 1 197 ? 31.89822  -9.58220  -18.43582 1.000 25.02887  ?  278 PHE A HD2  1 
ATOM   3050 H HE1  . PHE A 1 197 ? 28.63980  -8.61707  -14.84670 1.000 31.01707  ?  278 PHE A HE1  1 
ATOM   3051 H HE2  . PHE A 1 197 ? 30.14159  -7.88842  -18.76402 1.000 27.35892  ?  278 PHE A HE2  1 
ATOM   3052 H HZ   . PHE A 1 197 ? 28.55386  -7.38572  -16.95906 1.000 25.14636  ?  278 PHE A HZ   1 
ATOM   3053 N N    . THR A 1 198 ? 35.27322  -12.07620 -15.27450 1.000 13.81008  ?  279 THR A N    1 
ATOM   3054 C CA   . THR A 1 198 ? 36.16821  -13.16491 -14.93299 1.000 14.26503  ?  279 THR A CA   1 
ATOM   3055 C C    . THR A 1 198 ? 36.67914  -13.01954 -13.50840 1.000 16.80223  ?  279 THR A C    1 
ATOM   3056 O O    . THR A 1 198 ? 36.79846  -14.01802 -12.78242 1.000 16.83756  ?  279 THR A O    1 
ATOM   3057 C CB   . THR A 1 198 ? 37.32794  -13.17095 -15.93514 1.000 18.05197  ?  279 THR A CB   1 
ATOM   3058 O OG1  . THR A 1 198 ? 36.83211  -13.57257 -17.22124 1.000 24.36884  ?  279 THR A OG1  1 
ATOM   3059 C CG2  . THR A 1 198 ? 38.39376  -14.13842 -15.48664 1.000 39.22186  ?  279 THR A CG2  1 
ATOM   3060 H H    A THR A 1 198 ? 35.61289  -11.46105 -16.01383 1.000 16.57209  ?  279 THR A H    1 
ATOM   3061 D D    B THR A 1 198 ? 35.61512  -11.46252 -16.01402 0.000 16.57209  ?  279 THR A D    1 
ATOM   3062 H HA   . THR A 1 198 ? 35.64488  -14.11895 -14.99646 1.000 17.11804  ?  279 THR A HA   1 
ATOM   3063 H HB   . THR A 1 198 ? 37.76952  -12.17688 -16.00533 1.000 21.66236  ?  279 THR A HB   1 
ATOM   3064 H HG21 . THR A 1 198 ? 37.93417  -15.05937 -15.12784 1.000 47.06623  ?  279 THR A HG21 1 
ATOM   3065 H HG22 . THR A 1 198 ? 39.05673  -14.37485 -16.31891 1.000 47.06623  ?  279 THR A HG22 1 
ATOM   3066 H HG23 . THR A 1 198 ? 38.98101  -13.69873 -14.68047 1.000 47.06623  ?  279 THR A HG23 1 
ATOM   3067 N N    . GLN A 1 199 ? 36.99887  -11.79562 -13.08337 1.000 13.48763  ?  280 GLN A N    1 
ATOM   3068 C CA   A GLN A 1 199 ? 37.45353  -11.62612 -11.71034 0.453 15.19413  ?  280 GLN A CA   1 
ATOM   3069 C CA   B GLN A 1 199 ? 37.42532  -11.55576 -11.70619 0.547 15.17488  ?  280 GLN A CA   1 
ATOM   3070 C C    . GLN A 1 199 ? 36.35266  -11.99574 -10.71755 1.000 17.04297  ?  280 GLN A C    1 
ATOM   3071 O O    . GLN A 1 199 ? 36.63911  -12.59914 -9.67749  1.000 16.91375  ?  280 GLN A O    1 
ATOM   3072 C CB   A GLN A 1 199 ? 37.97626  -10.21897 -11.43711 0.453 18.18329  ?  280 GLN A CB   1 
ATOM   3073 C CB   B GLN A 1 199 ? 37.71345  -10.05858 -11.55037 0.547 17.88920  ?  280 GLN A CB   1 
ATOM   3074 C CG   A GLN A 1 199 ? 38.59670  -10.05078 -10.03194 0.453 27.99819  ?  280 GLN A CG   1 
ATOM   3075 C CG   B GLN A 1 199 ? 37.78909  -9.50463  -10.14011 0.547 24.12540  ?  280 GLN A CG   1 
ATOM   3076 C CD   A GLN A 1 199 ? 39.68006  -11.09638 -9.69880  0.453 37.90316  ?  280 GLN A CD   1 
ATOM   3077 C CD   B GLN A 1 199 ? 38.06253  -7.99394  -10.12870 0.547 36.72459  ?  280 GLN A CD   1 
ATOM   3078 O OE1  A GLN A 1 199 ? 39.73234  -11.61028 -8.57734  0.453 28.69862  ?  280 GLN A OE1  1 
ATOM   3079 O OE1  B GLN A 1 199 ? 38.95014  -7.50145  -10.83168 0.547 36.27496  ?  280 GLN A OE1  1 
ATOM   3080 N NE2  A GLN A 1 199 ? 40.54516  -11.40062 -10.66686 0.453 40.49814  ?  280 GLN A NE2  1 
ATOM   3081 N NE2  B GLN A 1 199 ? 37.28196  -7.25468  -9.33845  0.547 38.35998  ?  280 GLN A NE2  1 
ATOM   3082 H H    A GLN A 1 199 ? 36.95488  -10.94296 -13.64144 0.453 16.18516  ?  280 GLN A H    1 
ATOM   3083 H H    B GLN A 1 199 ? 36.97326  -10.95652 -13.66274 0.547 16.18516  ?  280 GLN A H    1 
ATOM   3084 H HA   A GLN A 1 199 ? 38.30065  -12.29656 -11.56546 0.453 18.23295  ?  280 GLN A HA   1 
ATOM   3085 H HA   B GLN A 1 199 ? 38.32948  -12.12408 -11.48802 0.547 18.20985  ?  280 GLN A HA   1 
ATOM   3086 H HB2  A GLN A 1 199 ? 38.74560  -9.98159  -12.17185 0.453 21.81995  ?  280 GLN A HB2  1 
ATOM   3087 H HB2  B GLN A 1 199 ? 38.67434  -9.85228  -12.02179 0.547 21.46704  ?  280 GLN A HB2  1 
ATOM   3088 H HB3  A GLN A 1 199 ? 37.14892  -9.51449  -11.52275 0.453 21.81995  ?  280 GLN A HB3  1 
ATOM   3089 H HB3  B GLN A 1 199 ? 36.92199  -9.51085  -12.06192 0.547 21.46704  ?  280 GLN A HB3  1 
ATOM   3090 H HG2  A GLN A 1 199 ? 39.05661  -9.06464  -9.96776  0.453 33.59782  ?  280 GLN A HG2  1 
ATOM   3091 H HG2  B GLN A 1 199 ? 36.84041  -9.68278  -9.63379  0.547 28.95048  ?  280 GLN A HG2  1 
ATOM   3092 H HG3  A GLN A 1 199 ? 37.80657  -10.14284 -9.28675  0.453 33.59782  ?  280 GLN A HG3  1 
ATOM   3093 H HG3  B GLN A 1 199 ? 38.59730  -10.00102 -9.60301  0.547 28.95048  ?  280 GLN A HG3  1 
ATOM   3094 N N    . VAL A 1 200 ? 35.08596  -11.68102 -11.02332 1.000 13.75642  ?  281 VAL A N    1 
ATOM   3095 C CA   . VAL A 1 200 ? 33.99653  -12.03123 -10.12133 1.000 14.17845  ?  281 VAL A CA   1 
ATOM   3096 C C    . VAL A 1 200 ? 33.82584  -13.54995 -10.06422 1.000 11.73011  ?  281 VAL A C    1 
ATOM   3097 O O    . VAL A 1 200 ? 33.64801  -14.12340 -8.98986  1.000 12.66711  ?  281 VAL A O    1 
ATOM   3098 C CB   . VAL A 1 200 ? 32.70253  -11.29377 -10.58178 1.000 13.88860  ?  281 VAL A CB   1 
ATOM   3099 C CG1  . VAL A 1 200 ? 31.48191  -11.80543 -9.82617  1.000 13.33811  ?  281 VAL A CG1  1 
ATOM   3100 C CG2  . VAL A 1 200 ? 32.87317  -9.78659  -10.47238 1.000 14.72421  ?  281 VAL A CG2  1 
ATOM   3101 H H    A VAL A 1 200 ? 34.79429  -11.19432 -11.87093 1.000 16.50771  ?  281 VAL A H    1 
ATOM   3102 D D    B VAL A 1 200 ? 34.79199  -11.19443 -11.87020 0.000 16.50771  ?  281 VAL A D    1 
ATOM   3103 H HA   . VAL A 1 200 ? 34.22887  -11.70235 -9.10844  1.000 17.01414  ?  281 VAL A HA   1 
ATOM   3104 H HB   . VAL A 1 200 ? 32.52361  -11.51170 -11.63467 1.000 16.66632  ?  281 VAL A HB   1 
ATOM   3105 H HG11 . VAL A 1 200 ? 30.66856  -11.96686 -10.53363 1.000 16.00574  ?  281 VAL A HG11 1 
ATOM   3106 H HG12 . VAL A 1 200 ? 31.73726  -12.74337 -9.33305  1.000 16.00574  ?  281 VAL A HG12 1 
ATOM   3107 H HG13 . VAL A 1 200 ? 31.18725  -11.06350 -9.08401  1.000 16.00574  ?  281 VAL A HG13 1 
ATOM   3108 H HG21 . VAL A 1 200 ? 33.79618  -9.49659  -10.97443 1.000 17.66905  ?  281 VAL A HG21 1 
ATOM   3109 H HG22 . VAL A 1 200 ? 32.02242  -9.29775  -10.94711 1.000 17.66905  ?  281 VAL A HG22 1 
ATOM   3110 H HG23 . VAL A 1 200 ? 32.92036  -9.51032  -9.41903  1.000 17.66905  ?  281 VAL A HG23 1 
ATOM   3111 N N    . TRP A 1 201 ? 33.88777  -14.21382 -11.20877 1.000 11.90690  ?  282 TRP A N    1 
ATOM   3112 C CA   . TRP A 1 201 ? 33.81528  -15.67743 -11.27447 1.000 14.14612  ?  282 TRP A CA   1 
ATOM   3113 C C    . TRP A 1 201 ? 34.94759  -16.32320 -10.45327 1.000 14.61298  ?  282 TRP A C    1 
ATOM   3114 O O    . TRP A 1 201 ? 34.72169  -17.27430 -9.70187  1.000 15.36243  ?  282 TRP A O    1 
ATOM   3115 C CB   . TRP A 1 201 ? 33.84418  -16.07386 -12.74387 1.000 13.95334  ?  282 TRP A CB   1 
ATOM   3116 C CG   . TRP A 1 201 ? 34.05078  -17.55650 -13.09242 1.000 14.24244  ?  282 TRP A CG   1 
ATOM   3117 C CD1  . TRP A 1 201 ? 33.13462  -18.55055 -12.99249 1.000 14.62611  ?  282 TRP A CD1  1 
ATOM   3118 C CD2  . TRP A 1 201 ? 35.24327  -18.16223 -13.63565 1.000 15.23727  ?  282 TRP A CD2  1 
ATOM   3119 N NE1  . TRP A 1 201 ? 33.68957  -19.74433 -13.43777 1.000 15.31041  ?  282 TRP A NE1  1 
ATOM   3120 C CE2  . TRP A 1 201 ? 34.97488  -19.51847 -13.84109 1.000 16.81498  ?  282 TRP A CE2  1 
ATOM   3121 C CE3  . TRP A 1 201 ? 36.49844  -17.65553 -13.99272 1.000 18.35304  ?  282 TRP A CE3  1 
ATOM   3122 C CZ2  . TRP A 1 201 ? 35.92634  -20.39275 -14.36125 1.000 17.53688  ?  282 TRP A CZ2  1 
ATOM   3123 C CZ3  . TRP A 1 201 ? 37.44619  -18.52218 -14.52411 1.000 18.87023  ?  282 TRP A CZ3  1 
ATOM   3124 C CH2  . TRP A 1 201 ? 37.14214  -19.86922 -14.69827 1.000 19.85830  ?  282 TRP A CH2  1 
ATOM   3125 H H    A TRP A 1 201 ? 33.98906  -13.77188 -12.12246 0.901 14.28828  ?  282 TRP A H    1 
ATOM   3126 D D    B TRP A 1 201 ? 33.98903  -13.77439 -12.12367 0.099 14.28828  ?  282 TRP A D    1 
ATOM   3127 H HA   . TRP A 1 201 ? 32.88735  -16.05232 -10.84261 1.000 16.97534  ?  282 TRP A HA   1 
ATOM   3128 H HB2  . TRP A 1 201 ? 32.89134  -15.78067 -13.18459 1.000 16.74401  ?  282 TRP A HB2  1 
ATOM   3129 H HB3  . TRP A 1 201 ? 34.65858  -15.52645 -13.21841 1.000 16.74401  ?  282 TRP A HB3  1 
ATOM   3130 H HD1  . TRP A 1 201 ? 32.12666  -18.43273 -12.62301 1.000 17.55133  ?  282 TRP A HD1  1 
ATOM   3131 H HE3  . TRP A 1 201 ? 36.72653  -16.60859 -13.85751 1.000 22.02365  ?  282 TRP A HE3  1 
ATOM   3132 H HZ2  . TRP A 1 201 ? 35.71131  -21.44292 -14.49287 1.000 21.04426  ?  282 TRP A HZ2  1 
ATOM   3133 H HZ3  . TRP A 1 201 ? 38.42087  -18.14953 -14.80256 1.000 22.64428  ?  282 TRP A HZ3  1 
ATOM   3134 H HH2  . TRP A 1 201 ? 37.89388  -20.52347 -15.11448 1.000 23.82996  ?  282 TRP A HH2  1 
ATOM   3135 N N    . GLN A 1 202 ? 36.17676  -15.78084 -10.54561 1.000 14.17969  ?  283 GLN A N    1 
ATOM   3136 C CA   . GLN A 1 202 ? 37.29922  -16.32266 -9.79781  1.000 15.05246  ?  283 GLN A CA   1 
ATOM   3137 C C    . GLN A 1 202 ? 37.10241  -16.11961 -8.30073  1.000 16.15352  ?  283 GLN A C    1 
ATOM   3138 O O    . GLN A 1 202 ? 37.38266  -17.01849 -7.49237  1.000 15.88933  ?  283 GLN A O    1 
ATOM   3139 C CB   . GLN A 1 202 ? 38.56867  -15.60441 -10.20492 1.000 20.77507  ?  283 GLN A CB   1 
ATOM   3140 C CG   . GLN A 1 202 ? 39.34315  -16.34522 -11.28006 1.000 49.84457  ?  283 GLN A CG   1 
ATOM   3141 C CD   . GLN A 1 202 ? 40.45771  -15.49928 -11.85489 1.000 57.32150  ?  283 GLN A CD   1 
ATOM   3142 O OE1  . GLN A 1 202 ? 40.90365  -14.53281 -11.23154 1.000 49.65595  ?  283 GLN A OE1  1 
ATOM   3143 N NE2  . GLN A 1 202 ? 40.90249  -15.84997 -13.06640 1.000 61.36143  ?  283 GLN A NE2  1 
ATOM   3144 H H    A GLN A 1 202 ? 36.41237  -14.97574 -11.12587 0.995 17.01562  ?  283 GLN A H    1 
ATOM   3145 D D    B GLN A 1 202 ? 36.41466  -14.97587 -11.12512 0.005 17.01562  ?  283 GLN A D    1 
ATOM   3146 H HA   . GLN A 1 202 ? 37.38064  -17.38691 -10.01879 1.000 18.06295  ?  283 GLN A HA   1 
ATOM   3147 H HB2  . GLN A 1 202 ? 38.30996  -14.61936 -10.59332 1.000 24.93009  ?  283 GLN A HB2  1 
ATOM   3148 H HB3  . GLN A 1 202 ? 39.21444  -15.50339 -9.33264  1.000 24.93009  ?  283 GLN A HB3  1 
ATOM   3149 H HG2  . GLN A 1 202 ? 39.78418  -17.24441 -10.84988 1.000 59.81348  ?  283 GLN A HG2  1 
ATOM   3150 H HG3  . GLN A 1 202 ? 38.66543  -16.61345 -12.09053 1.000 59.81348  ?  283 GLN A HG3  1 
ATOM   3151 N N    . ASN A 1 203 ? 36.67771  -14.91934 -7.88172  1.000 14.73712  ?  284 ASN A N    1 
ATOM   3152 C CA   . ASN A 1 203 ? 36.53028  -14.65042 -6.47232  1.000 14.45202  ?  284 ASN A CA   1 
ATOM   3153 C C    . ASN A 1 203 ? 35.49012  -15.55427 -5.83884  1.000 16.63150  ?  284 ASN A C    1 
ATOM   3154 O O    . ASN A 1 203 ? 35.55647  -15.85753 -4.63788  1.000 17.83994  ?  284 ASN A O    1 
ATOM   3155 C CB   . ASN A 1 203 ? 36.17045  -13.19187 -6.21340  1.000 18.11556  ?  284 ASN A CB   1 
ATOM   3156 C CG   . ASN A 1 203 ? 37.37581  -12.30709 -6.09568  1.000 32.86286  ?  284 ASN A CG   1 
ATOM   3157 O OD1  . ASN A 1 203 ? 38.47650  -12.77948 -5.82043  1.000 38.34010  ?  284 ASN A OD1  1 
ATOM   3158 N ND2  . ASN A 1 203 ? 37.17987  -11.00636 -6.29433  1.000 48.12747  ?  284 ASN A ND2  1 
ATOM   3159 H H    A ASN A 1 203 ? 36.43648  -14.13842 -8.49194  0.965 17.68455  ?  284 ASN A H    1 
ATOM   3160 D D    B ASN A 1 203 ? 36.43588  -14.13693 -8.48980  0.035 17.68455  ?  284 ASN A D    1 
ATOM   3161 H HA   . ASN A 1 203 ? 37.49543  -14.83528 -6.00073  1.000 17.34242  ?  284 ASN A HA   1 
ATOM   3162 H HB2  . ASN A 1 203 ? 35.56238  -12.82425 -7.03997  1.000 21.73867  ?  284 ASN A HB2  1 
ATOM   3163 H HB3  . ASN A 1 203 ? 35.61102  -13.12462 -5.28033  1.000 21.73867  ?  284 ASN A HB3  1 
ATOM   3164 N N    . ALA A 1 204 ? 34.49727  -15.96592 -6.59110  1.000 13.19544  ?  285 ALA A N    1 
ATOM   3165 C CA   . ALA A 1 204 ? 33.44454  -16.84197 -6.09589  1.000 14.18995  ?  285 ALA A CA   1 
ATOM   3166 C C    . ALA A 1 204 ? 33.80227  -18.31019 -6.20267  1.000 17.09498  ?  285 ALA A C    1 
ATOM   3167 O O    . ALA A 1 204 ? 32.97202  -19.16228 -5.91679  1.000 24.10457  ?  285 ALA A O    1 
ATOM   3168 C CB   . ALA A 1 204 ? 32.12424  -16.55832 -6.83378  1.000 14.63382  ?  285 ALA A CB   1 
ATOM   3169 H H    A ALA A 1 204 ? 34.38355  -15.70898 -7.57163  1.000 15.83453  ?  285 ALA A H    1 
ATOM   3170 D D    B ALA A 1 204 ? 34.38462  -15.70829 -7.57157  0.000 15.83453  ?  285 ALA A D    1 
ATOM   3171 H HA   . ALA A 1 204 ? 33.27625  -16.62524 -5.04100  1.000 17.02794  ?  285 ALA A HA   1 
ATOM   3172 H HB1  . ALA A 1 204 ? 31.83409  -15.52270 -6.65661  1.000 17.56058  ?  285 ALA A HB1  1 
ATOM   3173 H HB2  . ALA A 1 204 ? 32.27095  -16.72589 -7.90079  1.000 17.56058  ?  285 ALA A HB2  1 
ATOM   3174 H HB3  . ALA A 1 204 ? 31.35428  -17.23015 -6.45443  1.000 17.56058  ?  285 ALA A HB3  1 
ATOM   3175 N N    . GLY A 1 205 ? 35.00790  -18.63155 -6.60360  1.000 13.64729  ?  286 GLY A N    1 
ATOM   3176 C CA   . GLY A 1 205 ? 35.48666  -19.98902 -6.58827  1.000 16.86205  ?  286 GLY A CA   1 
ATOM   3177 C C    . GLY A 1 205 ? 35.29332  -20.76292 -7.86238  1.000 15.66895  ?  286 GLY A C    1 
ATOM   3178 O O    . GLY A 1 205 ? 35.48081  -21.97992 -7.86327  1.000 17.42292  ?  286 GLY A O    1 
ATOM   3179 H H    A GLY A 1 205 ? 35.69192  -17.96002 -6.95226  0.697 16.37675  ?  286 GLY A H    1 
ATOM   3180 D D    B GLY A 1 205 ? 35.69173  -17.95981 -6.95222  0.303 16.37675  ?  286 GLY A D    1 
ATOM   3181 H HA2  . GLY A 1 205 ? 36.55467  -19.97591 -6.37085  1.000 20.23446  ?  286 GLY A HA2  1 
ATOM   3182 H HA3  . GLY A 1 205 ? 34.96956  -20.52845 -5.79471  1.000 20.23446  ?  286 GLY A HA3  1 
ATOM   3183 N N    . LYS A 1 206 ? 34.90883  -20.10910 -8.95438  1.000 13.77451  ?  287 LYS A N    1 
ATOM   3184 C CA   . LYS A 1 206 ? 34.80146  -20.77382 -10.25888 1.000 13.27154  ?  287 LYS A CA   1 
ATOM   3185 C C    . LYS A 1 206 ? 33.77390  -21.89307 -10.23497 1.000 13.76501  ?  287 LYS A C    1 
ATOM   3186 O O    . LYS A 1 206 ? 33.91184  -22.88072 -10.94019 1.000 16.23239  ?  287 LYS A O    1 
ATOM   3187 C CB   . LYS A 1 206 ? 36.12347  -21.30223 -10.79543 1.000 16.42872  ?  287 LYS A CB   1 
ATOM   3188 C CG   . LYS A 1 206 ? 37.27494  -20.28910 -10.77197 1.000 18.83160  ?  287 LYS A CG   1 
ATOM   3189 C CD   . LYS A 1 206 ? 38.54489  -20.89324 -11.31848 1.000 24.73516  ?  287 LYS A CD   1 
ATOM   3190 C CE   . LYS A 1 206 ? 39.65718  -19.84184 -11.31184 1.000 47.85425  ?  287 LYS A CE   1 
ATOM   3191 N NZ   . LYS A 1 206 ? 40.94331  -20.38494 -11.76326 1.000 46.96939  ?  287 LYS A NZ   1 
ATOM   3192 H H    A LYS A 1 206 ? 34.66407  -19.11907 -8.97260  0.691 16.52941  ?  287 LYS A H    1 
ATOM   3193 D D    B LYS A 1 206 ? 34.66431  -19.11899 -8.97134  0.309 16.52941  ?  287 LYS A D    1 
ATOM   3194 H HA   . LYS A 1 206 ? 34.47139  -20.00601 -10.95861 1.000 15.92585  ?  287 LYS A HA   1 
ATOM   3195 H HB2  . LYS A 1 206 ? 36.42588  -22.15709 -10.19056 1.000 19.71447  ?  287 LYS A HB2  1 
ATOM   3196 H HB3  . LYS A 1 206 ? 35.97857  -21.61072 -11.83077 1.000 19.71447  ?  287 LYS A HB3  1 
ATOM   3197 H HG2  . LYS A 1 206 ? 37.01203  -19.42758 -11.38578 1.000 22.59792  ?  287 LYS A HG2  1 
ATOM   3198 H HG3  . LYS A 1 206 ? 37.45858  -19.97309 -9.74507  1.000 22.59792  ?  287 LYS A HG3  1 
ATOM   3199 H HD2  . LYS A 1 206 ? 38.85172  -21.73365 -10.69586 1.000 29.68219  ?  287 LYS A HD2  1 
ATOM   3200 H HD3  . LYS A 1 206 ? 38.38343  -21.22784 -12.34321 1.000 29.68219  ?  287 LYS A HD3  1 
ATOM   3201 H HE2  . LYS A 1 206 ? 39.38112  -19.02603 -11.97993 1.000 57.42510  ?  287 LYS A HE2  1 
ATOM   3202 H HE3  . LYS A 1 206 ? 39.78628  -19.46528 -10.29713 1.000 57.42510  ?  287 LYS A HE3  1 
ATOM   3203 N N    . SER A 1 207 ? 32.70913  -21.73418 -9.46334  1.000 12.15475  ?  288 SER A N    1 
ATOM   3204 C CA   . SER A 1 207 ? 31.73127  -22.76847 -9.31798  1.000 12.58241  ?  288 SER A CA   1 
ATOM   3205 C C    . SER A 1 207 ? 31.10246  -23.07824 -10.66756 1.000 13.14222  ?  288 SER A C    1 
ATOM   3206 O O    . SER A 1 207 ? 30.72910  -22.15781 -11.40010 1.000 13.06128  ?  288 SER A O    1 
ATOM   3207 C CB   . SER A 1 207 ? 30.61317  -22.31944 -8.37281  1.000 14.49117  ?  288 SER A CB   1 
ATOM   3208 O OG   . SER A 1 207 ? 29.61560  -23.33171 -8.32598  1.000 16.04241  ?  288 SER A OG   1 
ATOM   3209 H H    A SER A 1 207 ? 32.50428  -20.89106 -8.92708  0.696 14.58570  ?  288 SER A H    1 
ATOM   3210 D D    B SER A 1 207 ? 32.50217  -20.89213 -8.92621  0.304 14.58570  ?  288 SER A D    1 
ATOM   3211 H HA   . SER A 1 207 ? 32.21703  -23.65868 -8.91841  1.000 15.09889  ?  288 SER A HA   1 
ATOM   3212 H HB2  . SER A 1 207 ? 31.02155  -22.16503 -7.37407  1.000 17.38941  ?  288 SER A HB2  1 
ATOM   3213 H HB3  . SER A 1 207 ? 30.17404  -21.39317 -8.74333  1.000 17.38941  ?  288 SER A HB3  1 
ATOM   3214 N N    . PRO A 1 208 ? 30.88773  -24.35461 -10.98482 1.000 12.63466  ?  289 PRO A N    1 
ATOM   3215 C CA   . PRO A 1 208 ? 30.18100  -24.70682 -12.20767 1.000 13.85599  ?  289 PRO A CA   1 
ATOM   3216 C C    . PRO A 1 208 ? 28.77551  -24.17752 -12.25304 1.000 12.87180  ?  289 PRO A C    1 
ATOM   3217 O O    . PRO A 1 208 ? 28.19757  -24.08930 -13.34285 1.000 14.89685  ?  289 PRO A O    1 
ATOM   3218 C CB   . PRO A 1 208 ? 30.16774  -26.24568 -12.18347 1.000 15.65457  ?  289 PRO A CB   1 
ATOM   3219 C CG   . PRO A 1 208 ? 31.25704  -26.61779 -11.30562 1.000 24.54288  ?  289 PRO A CG   1 
ATOM   3220 C CD   . PRO A 1 208 ? 31.41519  -25.53721 -10.29405 1.000 15.88043  ?  289 PRO A CD   1 
ATOM   3221 H HA   . PRO A 1 208 ? 30.74435  -24.35488 -13.07189 1.000 16.62718  ?  289 PRO A HA   1 
ATOM   3222 H HB2  . PRO A 1 208 ? 29.21412  -26.60204 -11.79396 1.000 18.78548  ?  289 PRO A HB2  1 
ATOM   3223 H HB3  . PRO A 1 208 ? 30.32793  -26.63358 -13.18943 1.000 18.78548  ?  289 PRO A HB3  1 
ATOM   3224 H HG2  . PRO A 1 208 ? 31.01687  -27.56162 -10.81614 1.000 29.45146  ?  289 PRO A HG2  1 
ATOM   3225 H HG3  . PRO A 1 208 ? 32.16996  -26.72350 -11.89171 1.000 29.45146  ?  289 PRO A HG3  1 
ATOM   3226 H HD2  . PRO A 1 208 ? 30.83406  -25.75544 -9.39808  1.000 19.05651  ?  289 PRO A HD2  1 
ATOM   3227 H HD3  . PRO A 1 208 ? 32.46454  -25.39932 -10.03340 1.000 19.05651  ?  289 PRO A HD3  1 
ATOM   3228 N N    . PHE A 1 209 ? 28.20169  -23.81645 -11.11077 1.000 11.30801  ?  290 PHE A N    1 
ATOM   3229 C CA   . PHE A 1 209 ? 26.83981  -23.28001 -11.10159 1.000 11.76965  ?  290 PHE A CA   1 
ATOM   3230 C C    . PHE A 1 209 ? 26.79989  -21.86425 -11.61429 1.000 11.26828  ?  290 PHE A C    1 
ATOM   3231 O O    . PHE A 1 209 ? 25.71197  -21.37060 -11.92158 1.000 12.77519  ?  290 PHE A O    1 
ATOM   3232 C CB   . PHE A 1 209 ? 26.24336  -23.35289 -9.71207  1.000 12.38817  ?  290 PHE A CB   1 
ATOM   3233 C CG   . PHE A 1 209 ? 25.94715  -24.75655 -9.27716  1.000 12.58048  ?  290 PHE A CG   1 
ATOM   3234 C CD1  . PHE A 1 209 ? 24.93592  -25.49008 -9.87053  1.000 14.24489  ?  290 PHE A CD1  1 
ATOM   3235 C CD2  . PHE A 1 209 ? 26.74806  -25.34582 -8.31201  1.000 13.78260  ?  290 PHE A CD2  1 
ATOM   3236 C CE1  . PHE A 1 209 ? 24.68498  -26.79406 -9.47158  1.000 15.22785  ?  290 PHE A CE1  1 
ATOM   3237 C CE2  . PHE A 1 209 ? 26.50121  -26.63859 -7.93118  1.000 16.21957  ?  290 PHE A CE2  1 
ATOM   3238 C CZ   . PHE A 1 209 ? 25.48958  -27.35408 -8.51095  1.000 14.31053  ?  290 PHE A CZ   1 
ATOM   3239 H H    A PHE A 1 209 ? 28.64011  -23.87981 -10.19198 0.593 13.56961  ?  290 PHE A H    1 
ATOM   3240 D D    B PHE A 1 209 ? 28.63859  -23.87912 -10.19122 0.407 13.56961  ?  290 PHE A D    1 
ATOM   3241 H HA   . PHE A 1 209 ? 26.21406  -23.89646 -11.74698 1.000 14.12358  ?  290 PHE A HA   1 
ATOM   3242 H HB2  . PHE A 1 209 ? 26.94811  -22.92169 -9.00109  1.000 14.86580  ?  290 PHE A HB2  1 
ATOM   3243 H HB3  . PHE A 1 209 ? 25.30904  -22.79168 -9.69784  1.000 14.86580  ?  290 PHE A HB3  1 
ATOM   3244 H HD1  . PHE A 1 209 ? 24.33709  -25.04377 -10.65067 1.000 17.09386  ?  290 PHE A HD1  1 
ATOM   3245 H HD2  . PHE A 1 209 ? 27.55934  -24.79119 -7.86413  1.000 16.53912  ?  290 PHE A HD2  1 
ATOM   3246 H HE1  . PHE A 1 209 ? 23.87326  -27.35739 -9.90766  1.000 18.27341  ?  290 PHE A HE1  1 
ATOM   3247 H HE2  . PHE A 1 209 ? 27.11073  -27.09687 -7.16643  1.000 19.46348  ?  290 PHE A HE2  1 
ATOM   3248 H HZ   . PHE A 1 209 ? 25.32121  -28.37685 -8.20765  1.000 17.17264  ?  290 PHE A HZ   1 
ATOM   3249 N N    . ILE A 1 210 ? 27.92912  -21.17113 -11.66763 1.000 12.09106  ?  291 ILE A N    1 
ATOM   3250 C CA   . ILE A 1 210 ? 28.01423  -19.83401 -12.28598 1.000 11.34880  ?  291 ILE A CA   1 
ATOM   3251 C C    . ILE A 1 210 ? 28.13896  -20.07878 -13.78235 1.000 12.47650  ?  291 ILE A C    1 
ATOM   3252 O O    . ILE A 1 210 ? 29.25831  -20.20231 -14.32532 1.000 13.20446  ?  291 ILE A O    1 
ATOM   3253 C CB   . ILE A 1 210 ? 29.17411  -19.01571 -11.71508 1.000 13.91153  ?  291 ILE A CB   1 
ATOM   3254 C CG1  . ILE A 1 210 ? 29.09613  -18.89190 -10.19763 1.000 13.34241  ?  291 ILE A CG1  1 
ATOM   3255 C CG2  . ILE A 1 210 ? 29.17805  -17.63602 -12.33579 1.000 14.95453  ?  291 ILE A CG2  1 
ATOM   3256 C CD1  . ILE A 1 210 ? 30.37232  -18.32727 -9.61396  1.000 17.83668  ?  291 ILE A CD1  1 
ATOM   3257 H H    A ILE A 1 210 ? 28.81761  -21.50141 -11.29094 1.000 14.50927  ?  291 ILE A H    1 
ATOM   3258 D D    B ILE A 1 210 ? 28.81738  -21.50184 -11.29078 0.000 14.50927  ?  291 ILE A D    1 
ATOM   3259 H HA   . ILE A 1 210 ? 27.12085  -19.24226 -12.08647 1.000 13.61856  ?  291 ILE A HA   1 
ATOM   3260 H HB   . ILE A 1 210 ? 30.09620  -19.54357 -11.95840 1.000 16.69383  ?  291 ILE A HB   1 
ATOM   3261 H HG12 . ILE A 1 210 ? 28.27507  -18.22539 -9.93357  1.000 16.01089  ?  291 ILE A HG12 1 
ATOM   3262 H HG13 . ILE A 1 210 ? 28.92935  -19.87839 -9.76507  1.000 16.01089  ?  291 ILE A HG13 1 
ATOM   3263 H HG21 . ILE A 1 210 ? 28.21292  -17.16280 -12.15499 1.000 17.94543  ?  291 ILE A HG21 1 
ATOM   3264 H HG22 . ILE A 1 210 ? 29.97293  -17.04468 -11.88129 1.000 17.94543  ?  291 ILE A HG22 1 
ATOM   3265 H HG23 . ILE A 1 210 ? 29.35106  -17.72971 -13.40789 1.000 17.94543  ?  291 ILE A HG23 1 
ATOM   3266 H HD11 . ILE A 1 210 ? 30.36879  -18.48366 -8.53525  1.000 21.40401  ?  291 ILE A HD11 1 
ATOM   3267 H HD12 . ILE A 1 210 ? 31.22415  -18.83971 -10.06106 1.000 21.40401  ?  291 ILE A HD12 1 
ATOM   3268 H HD13 . ILE A 1 210 ? 30.42221  -17.26104 -9.83480  1.000 21.40401  ?  291 ILE A HD13 1 
ATOM   3269 N N    . LYS A 1 211 ? 27.00510  -20.18898 -14.44769 1.000 10.89338  ?  292 LYS A N    1 
ATOM   3270 C CA   A LYS A 1 211 ? 26.95523  -20.66761 -15.82900 0.540 11.75321  ?  292 LYS A CA   1 
ATOM   3271 C CA   B LYS A 1 211 ? 26.97240  -20.67488 -15.82933 0.460 11.72689  ?  292 LYS A CA   1 
ATOM   3272 C C    . LYS A 1 211 ? 27.46103  -19.63406 -16.83167 1.000 11.41635  ?  292 LYS A C    1 
ATOM   3273 O O    . LYS A 1 211 ? 28.08306  -19.98758 -17.82911 1.000 11.59784  ?  292 LYS A O    1 
ATOM   3274 C CB   A LYS A 1 211 ? 25.53490  -21.05729 -16.24920 0.540 15.24772  ?  292 LYS A CB   1 
ATOM   3275 C CB   B LYS A 1 211 ? 25.55872  -21.18455 -16.12719 0.460 14.43695  ?  292 LYS A CB   1 
ATOM   3276 C CG   A LYS A 1 211 ? 25.00876  -22.35464 -15.70062 0.540 13.73531  ?  292 LYS A CG   1 
ATOM   3277 C CG   B LYS A 1 211 ? 25.40992  -22.04271 -17.35153 0.460 15.78783  ?  292 LYS A CG   1 
ATOM   3278 C CD   A LYS A 1 211 ? 25.78153  -23.59172 -16.15955 0.540 16.67211  ?  292 LYS A CD   1 
ATOM   3279 C CD   B LYS A 1 211 ? 25.96004  -23.46953 -17.17456 0.460 17.71354  ?  292 LYS A CD   1 
ATOM   3280 C CE   A LYS A 1 211 ? 25.52896  -23.97163 -17.60575 0.540 17.46370  ?  292 LYS A CE   1 
ATOM   3281 C CE   B LYS A 1 211 ? 26.31398  -24.09640 -18.53542 0.460 16.70277  ?  292 LYS A CE   1 
ATOM   3282 N NZ   A LYS A 1 211 ? 26.41789  -25.07757 -18.01446 0.540 20.31720  ?  292 LYS A NZ   1 
ATOM   3283 N NZ   B LYS A 1 211 ? 27.43198  -23.35986 -19.21918 0.460 20.75086  ?  292 LYS A NZ   1 
ATOM   3284 H H    A LYS A 1 211 ? 26.08956  -19.95513 -14.06364 0.540 13.07205  ?  292 LYS A H    1 
ATOM   3285 H H    B LYS A 1 211 ? 26.08790  -19.95320 -14.06881 0.460 13.07205  ?  292 LYS A H    1 
ATOM   3286 H HA   A LYS A 1 211 ? 27.59244  -21.55157 -15.85500 0.540 14.10385  ?  292 LYS A HA   1 
ATOM   3287 H HA   B LYS A 1 211 ? 27.65192  -21.51753 -15.95702 0.460 14.07227  ?  292 LYS A HA   1 
ATOM   3288 H HB2  A LYS A 1 211 ? 24.85595  -20.27113 -15.91890 0.540 18.29726  ?  292 LYS A HB2  1 
ATOM   3289 H HB2  B LYS A 1 211 ? 25.22475  -21.77800 -15.27608 0.460 17.32434  ?  292 LYS A HB2  1 
ATOM   3290 H HB3  A LYS A 1 211 ? 25.51270  -21.13671 -17.33607 0.540 18.29726  ?  292 LYS A HB3  1 
ATOM   3291 H HB3  B LYS A 1 211 ? 24.90651  -20.32115 -16.25853 0.460 17.32434  ?  292 LYS A HB3  1 
ATOM   3292 H HG2  A LYS A 1 211 ? 25.05987  -22.31963 -14.61238 0.540 16.48237  ?  292 LYS A HG2  1 
ATOM   3293 H HG2  B LYS A 1 211 ? 24.35135  -22.12273 -17.59880 0.460 18.94539  ?  292 LYS A HG2  1 
ATOM   3294 H HG3  A LYS A 1 211 ? 23.97407  -22.47513 -16.02155 0.540 16.48237  ?  292 LYS A HG3  1 
ATOM   3295 H HG3  B LYS A 1 211 ? 25.95107  -21.57746 -18.17542 0.460 18.94539  ?  292 LYS A HG3  1 
ATOM   3296 H HD2  A LYS A 1 211 ? 26.84877  -23.39966 -16.04909 0.540 20.00654  ?  292 LYS A HD2  1 
ATOM   3297 H HD2  B LYS A 1 211 ? 26.86250  -23.43783 -16.56408 0.460 21.25625  ?  292 LYS A HD2  1 
ATOM   3298 H HD3  A LYS A 1 211 ? 25.48889  -24.43848 -15.53870 0.540 20.00654  ?  292 LYS A HD3  1 
ATOM   3299 H HD3  B LYS A 1 211 ? 25.20611  -24.09250 -16.69332 0.460 21.25625  ?  292 LYS A HD3  1 
ATOM   3300 H HE2  A LYS A 1 211 ? 24.49494  -24.29610 -17.72248 0.540 20.95643  ?  292 LYS A HE2  1 
ATOM   3301 H HE2  B LYS A 1 211 ? 26.62866  -25.12895 -18.38407 0.460 20.04332  ?  292 LYS A HE2  1 
ATOM   3302 H HE3  A LYS A 1 211 ? 25.72506  -23.11311 -18.24808 0.540 20.95643  ?  292 LYS A HE3  1 
ATOM   3303 H HE3  B LYS A 1 211 ? 25.43841  -24.06474 -19.18385 0.460 20.04332  ?  292 LYS A HE3  1 
ATOM   3304 H HZ1  A LYS A 1 211 ? 25.91269  -25.72137 -18.65625 0.540 24.38064  ?  292 LYS A HZ1  1 
ATOM   3305 H HZ1  B LYS A 1 211 ? 27.04491  -22.70269 -19.92622 0.460 24.90103  ?  292 LYS A HZ1  1 
ATOM   3306 H HZ2  A LYS A 1 211 ? 27.25365  -24.69958 -18.50459 0.540 24.38064  ?  292 LYS A HZ2  1 
ATOM   3307 H HZ2  B LYS A 1 211 ? 27.98118  -22.81920 -18.52085 0.460 24.90103  ?  292 LYS A HZ2  1 
ATOM   3308 H HZ3  A LYS A 1 211 ? 26.72973  -25.61098 -17.17791 0.540 24.38064  ?  292 LYS A HZ3  1 
ATOM   3309 H HZ3  B LYS A 1 211 ? 28.06345  -24.03488 -19.69584 0.460 24.90103  ?  292 LYS A HZ3  1 
ATOM   3310 N N    . GLY A 1 212 ? 27.17467  -18.36217 -16.61977 1.000 11.10441  ?  293 GLY A N    1 
ATOM   3311 C CA   . GLY A 1 212 ? 27.56449  -17.36264 -17.57461 1.000 11.45882  ?  293 GLY A CA   1 
ATOM   3312 C C    . GLY A 1 212 ? 26.80355  -16.08083 -17.29438 1.000 11.13685  ?  293 GLY A C    1 
ATOM   3313 O O    . GLY A 1 212 ? 26.72265  -15.61845 -16.16229 1.000 10.66697  ?  293 GLY A O    1 
ATOM   3314 H H    A GLY A 1 212 ? 26.67911  -18.00398 -15.80337 1.000 13.32530  ?  293 GLY A H    1 
ATOM   3315 D D    B GLY A 1 212 ? 26.67915  -18.00348 -15.80356 0.000 13.32530  ?  293 GLY A D    1 
ATOM   3316 H HA2  . GLY A 1 212 ? 28.63437  -17.16880 -17.49797 1.000 13.75059  ?  293 GLY A HA2  1 
ATOM   3317 H HA3  . GLY A 1 212 ? 27.33673  -17.70142 -18.58528 1.000 13.75059  ?  293 GLY A HA3  1 
ATOM   3318 N N    . LEU A 1 213 ? 26.30687  -15.47849 -18.38674 1.000 9.69583   ?  294 LEU A N    1 
ATOM   3319 C CA   . LEU A 1 213 ? 25.82695  -14.09711 -18.39012 1.000 10.19880  ?  294 LEU A CA   1 
ATOM   3320 C C    . LEU A 1 213 ? 24.46623  -14.02510 -19.05217 1.000 10.22826  ?  294 LEU A C    1 
ATOM   3321 O O    . LEU A 1 213 ? 24.12865  -14.82666 -19.90760 1.000 10.66462  ?  294 LEU A O    1 
ATOM   3322 C CB   . LEU A 1 213 ? 26.82529  -13.16018 -19.16257 1.000 9.61178   ?  294 LEU A CB   1 
ATOM   3323 C CG   . LEU A 1 213 ? 28.22838  -13.19386 -18.61834 1.000 11.46607  ?  294 LEU A CG   1 
ATOM   3324 C CD1  . LEU A 1 213 ? 29.14182  -12.29186 -19.44994 1.000 13.86636  ?  294 LEU A CD1  1 
ATOM   3325 C CD2  . LEU A 1 213 ? 28.33755  -12.76268 -17.18625 1.000 13.57302  ?  294 LEU A CD2  1 
ATOM   3326 H H    A LEU A 1 213 ? 26.22558  -15.93450 -19.29550 0.934 11.63500  ?  294 LEU A H    1 
ATOM   3327 D D    B LEU A 1 213 ? 26.22626  -15.93595 -19.29483 0.066 11.63500  ?  294 LEU A D    1 
ATOM   3328 H HA   . LEU A 1 213 ? 25.72591  -13.74488 -17.36356 1.000 12.23857  ?  294 LEU A HA   1 
ATOM   3329 H HB2  . LEU A 1 213 ? 26.86398  -13.47389 -20.20573 1.000 11.53414  ?  294 LEU A HB2  1 
ATOM   3330 H HB3  . LEU A 1 213 ? 26.46537  -12.13353 -19.09513 1.000 11.53414  ?  294 LEU A HB3  1 
ATOM   3331 H HG   . LEU A 1 213 ? 28.54294  -14.23612 -18.67172 1.000 13.75928  ?  294 LEU A HG   1 
ATOM   3332 H HD11 . LEU A 1 213 ? 30.16917  -12.41417 -19.10687 1.000 16.63964  ?  294 LEU A HD11 1 
ATOM   3333 H HD12 . LEU A 1 213 ? 29.06366  -12.57795 -20.49882 1.000 16.63964  ?  294 LEU A HD12 1 
ATOM   3334 H HD13 . LEU A 1 213 ? 28.82842  -11.25564 -19.32296 1.000 16.63964  ?  294 LEU A HD13 1 
ATOM   3335 H HD21 . LEU A 1 213 ? 29.38629  -12.58514 -16.94806 1.000 16.28762  ?  294 LEU A HD21 1 
ATOM   3336 H HD22 . LEU A 1 213 ? 27.76441  -11.84605 -17.04695 1.000 16.28762  ?  294 LEU A HD22 1 
ATOM   3337 H HD23 . LEU A 1 213 ? 27.93946  -13.55074 -16.54704 1.000 16.28762  ?  294 LEU A HD23 1 
ATOM   3338 N N    . ALA A 1 214 ? 23.68563  -13.05195 -18.62888 1.000 10.37256  ?  295 ALA A N    1 
ATOM   3339 C CA   . ALA A 1 214 ? 22.38673  -12.72763 -19.21318 1.000 8.78249   ?  295 ALA A CA   1 
ATOM   3340 C C    . ALA A 1 214 ? 22.49895  -11.37531 -19.89799 1.000 8.78585   ?  295 ALA A C    1 
ATOM   3341 O O    . ALA A 1 214 ? 23.09165  -10.44760 -19.34829 1.000 11.68273  ?  295 ALA A O    1 
ATOM   3342 C CB   . ALA A 1 214 ? 21.31918  -12.61935 -18.15377 1.000 9.74761   ?  295 ALA A CB   1 
ATOM   3343 H H    A ALA A 1 214 ? 23.92888  -12.43993 -17.85000 0.921 12.44707  ?  295 ALA A H    1 
ATOM   3344 D D    B ALA A 1 214 ? 23.93090  -12.44108 -17.84973 0.079 12.44707  ?  295 ALA A D    1 
ATOM   3345 H HA   . ALA A 1 214 ? 22.10112  -13.50296 -19.92409 1.000 10.53899  ?  295 ALA A HA   1 
ATOM   3346 H HB1  . ALA A 1 214 ? 21.04023  -13.62122 -17.82736 1.000 11.69713  ?  295 ALA A HB1  1 
ATOM   3347 H HB2  . ALA A 1 214 ? 21.71168  -12.04978 -17.31137 1.000 11.69713  ?  295 ALA A HB2  1 
ATOM   3348 H HB3  . ALA A 1 214 ? 20.45190  -12.11059 -18.57460 1.000 11.69713  ?  295 ALA A HB3  1 
ATOM   3349 N N    . THR A 1 215 ? 21.93285  -11.24976 -21.12742 1.000 9.67387   ?  296 THR A N    1 
ATOM   3350 C CA   . THR A 1 215 ? 21.99143  -9.98666  -21.84715 1.000 9.09166   ?  296 THR A CA   1 
ATOM   3351 C C    . THR A 1 215 ? 20.59449  -9.52176  -22.23469 1.000 9.57549   ?  296 THR A C    1 
ATOM   3352 O O    . THR A 1 215 ? 19.63508  -10.32284 -22.29591 1.000 9.95799   ?  296 THR A O    1 
ATOM   3353 C CB   . THR A 1 215 ? 22.87831  -10.02962 -23.08028 1.000 10.74219  ?  296 THR A CB   1 
ATOM   3354 O OG1  . THR A 1 215 ? 22.19487  -10.67774 -24.16578 1.000 11.88899  ?  296 THR A OG1  1 
ATOM   3355 C CG2  . THR A 1 215 ? 24.19369  -10.75696 -22.83352 1.000 13.11084  ?  296 THR A CG2  1 
ATOM   3356 H H    A THR A 1 215 ? 21.44461  -11.99832 -21.61904 1.000 11.60865  ?  296 THR A H    1 
ATOM   3357 D D    B THR A 1 215 ? 21.44496  -11.99954 -21.61752 0.000 11.60865  ?  296 THR A D    1 
ATOM   3358 H HA   . THR A 1 215 ? 22.42594  -9.25172  -21.16953 1.000 10.91000  ?  296 THR A HA   1 
ATOM   3359 H HB   . THR A 1 215 ? 23.11383  -8.99856  -23.34397 1.000 12.89063  ?  296 THR A HB   1 
ATOM   3360 H HG21 . THR A 1 215 ? 24.71050  -10.92369 -23.77861 1.000 15.73300  ?  296 THR A HG21 1 
ATOM   3361 H HG22 . THR A 1 215 ? 24.83242  -10.16130 -22.18135 1.000 15.73300  ?  296 THR A HG22 1 
ATOM   3362 H HG23 . THR A 1 215 ? 24.00398  -11.71993 -22.35939 1.000 15.73300  ?  296 THR A HG23 1 
ATOM   3363 N N    . ASN A 1 216 ? 20.48829  -8.21459  -22.50972 1.000 9.27625   ?  297 ASN A N    1 
ATOM   3364 C CA   . ASN A 1 216 ? 19.26376  -7.57988  -23.00291 1.000 8.26616   ?  297 ASN A CA   1 
ATOM   3365 C C    . ASN A 1 216 ? 18.12848  -7.58878  -21.99166 1.000 9.40928   ?  297 ASN A C    1 
ATOM   3366 O O    . ASN A 1 216 ? 16.99292  -7.36153  -22.36127 1.000 9.82305   ?  297 ASN A O    1 
ATOM   3367 C CB   . ASN A 1 216 ? 18.79460  -8.19217  -24.32400 1.000 9.69761   ?  297 ASN A CB   1 
ATOM   3368 C CG   . ASN A 1 216 ? 18.02155  -7.22293  -25.18335 1.000 12.00449  ?  297 ASN A CG   1 
ATOM   3369 O OD1  . ASN A 1 216 ? 18.37260  -6.07785  -25.37609 1.000 11.92342  ?  297 ASN A OD1  1 
ATOM   3370 N ND2  . ASN A 1 216 ? 16.89138  -7.70290  -25.65415 1.000 13.34453  ?  297 ASN A ND2  1 
ATOM   3371 H H    A ASN A 1 216 ? 21.25800  -7.55502  -22.39608 0.883 11.13150  ?  297 ASN A H    1 
ATOM   3372 D D    B ASN A 1 216 ? 21.25995  -7.55749  -22.39502 0.117 11.13150  ?  297 ASN A D    1 
ATOM   3373 H HA   . ASN A 1 216 ? 19.50439  -6.53364  -23.19153 1.000 9.91939   ?  297 ASN A HA   1 
ATOM   3374 H HB2  . ASN A 1 216 ? 19.66567  -8.52171  -24.89033 1.000 11.63713  ?  297 ASN A HB2  1 
ATOM   3375 H HB3  . ASN A 1 216 ? 18.14606  -9.04162  -24.10971 1.000 11.63713  ?  297 ASN A HB3  1 
ATOM   3376 N N    . VAL A 1 217 ? 18.43174  -7.80495  -20.71147 1.000 9.03258   ?  298 VAL A N    1 
ATOM   3377 C CA   . VAL A 1 217 ? 17.37596  -7.86212  -19.68377 1.000 9.20549   ?  298 VAL A CA   1 
ATOM   3378 C C    . VAL A 1 217 ? 16.64697  -6.53610  -19.60905 1.000 9.27709   ?  298 VAL A C    1 
ATOM   3379 O O    . VAL A 1 217 ? 17.25275  -5.48320  -19.44567 1.000 11.13507  ?  298 VAL A O    1 
ATOM   3380 C CB   . VAL A 1 217 ? 17.99128  -8.23917  -18.32348 1.000 8.79883   ?  298 VAL A CB   1 
ATOM   3381 C CG1  . VAL A 1 217 ? 16.96910  -8.10421  -17.23878 1.000 10.40163  ?  298 VAL A CG1  1 
ATOM   3382 C CG2  . VAL A 1 217 ? 18.57832  -9.62175  -18.36124 1.000 11.15097  ?  298 VAL A CG2  1 
ATOM   3383 H H    A VAL A 1 217 ? 19.37673  -7.94249  -20.35302 0.749 10.83909  ?  298 VAL A H    1 
ATOM   3384 D D    B VAL A 1 217 ? 19.37599  -7.94270  -20.35116 0.251 10.83909  ?  298 VAL A D    1 
ATOM   3385 H HA   . VAL A 1 217 ? 16.65123  -8.62505  -19.96803 1.000 11.04658  ?  298 VAL A HA   1 
ATOM   3386 H HB   . VAL A 1 217 ? 18.80824  -7.55297  -18.10033 1.000 10.55860  ?  298 VAL A HB   1 
ATOM   3387 H HG11 . VAL A 1 217 ? 16.40985  -7.18109  -17.39105 1.000 12.48196  ?  298 VAL A HG11 1 
ATOM   3388 H HG12 . VAL A 1 217 ? 16.29381  -8.95888  -17.27920 1.000 12.48196  ?  298 VAL A HG12 1 
ATOM   3389 H HG13 . VAL A 1 217 ? 17.47648  -8.07666  -16.27447 1.000 12.48196  ?  298 VAL A HG13 1 
ATOM   3390 H HG21 . VAL A 1 217 ? 18.97421  -9.81207  -19.35882 1.000 13.38116  ?  298 VAL A HG21 1 
ATOM   3391 H HG22 . VAL A 1 217 ? 19.37917  -9.68748  -17.62475 1.000 13.38116  ?  298 VAL A HG22 1 
ATOM   3392 H HG23 . VAL A 1 217 ? 17.79754  -10.34533 -18.12691 1.000 13.38116  ?  298 VAL A HG23 1 
ATOM   3393 N N    . ALA A 1 218 ? 15.33479  -6.58690  -19.76634 1.000 10.31567  ?  299 ALA A N    1 
ATOM   3394 C CA   . ALA A 1 218 ? 14.45550  -5.41753  -19.75613 1.000 10.78990  ?  299 ALA A CA   1 
ATOM   3395 C C    . ALA A 1 218 ? 14.74958  -4.46222  -20.89665 1.000 11.03723  ?  299 ALA A C    1 
ATOM   3396 O O    . ALA A 1 218 ? 14.26462  -3.32880  -20.88926 1.000 14.10649  ?  299 ALA A O    1 
ATOM   3397 C CB   . ALA A 1 218 ? 14.51420  -4.66386  -18.42165 1.000 12.04560  ?  299 ALA A CB   1 
ATOM   3398 H H    A ALA A 1 218 ? 14.82563  -7.45910  -19.90927 0.628 12.37881  ?  299 ALA A H    1 
ATOM   3399 D D    B ALA A 1 218 ? 14.82918  -7.46120  -19.90906 0.372 12.37881  ?  299 ALA A D    1 
ATOM   3400 H HA   . ALA A 1 218 ? 13.43376  -5.77574  -19.88202 1.000 12.94788  ?  299 ALA A HA   1 
ATOM   3401 H HB1  . ALA A 1 218 ? 15.54799  -4.38610  -18.21615 1.000 14.45472  ?  299 ALA A HB1  1 
ATOM   3402 H HB2  . ALA A 1 218 ? 13.89585  -3.76899  -18.49199 1.000 14.45472  ?  299 ALA A HB2  1 
ATOM   3403 H HB3  . ALA A 1 218 ? 14.13953  -5.31334  -17.63051 1.000 14.45472  ?  299 ALA A HB3  1 
ATOM   3404 N N    . ASN A 1 219 ? 15.49283  -4.88505  -21.92089 1.000 10.39760  ?  300 ASN A N    1 
ATOM   3405 C CA   . ASN A 1 219 ? 15.76301  -4.01583  -23.05651 1.000 11.04864  ?  300 ASN A CA   1 
ATOM   3406 C C    . ASN A 1 219 ? 15.02585  -4.53653  -24.30944 1.000 10.44711  ?  300 ASN A C    1 
ATOM   3407 O O    . ASN A 1 219 ? 14.08092  -5.33925  -24.21964 1.000 10.89451  ?  300 ASN A O    1 
ATOM   3408 C CB   . ASN A 1 219 ? 17.26759  -3.86852  -23.22598 1.000 11.52991  ?  300 ASN A CB   1 
ATOM   3409 C CG   . ASN A 1 219 ? 17.64562  -2.51009  -23.78843 1.000 14.56187  ?  300 ASN A CG   1 
ATOM   3410 O OD1  . ASN A 1 219 ? 17.52382  -2.30103  -25.01012 1.000 15.37430  ?  300 ASN A OD1  1 
ATOM   3411 N ND2  . ASN A 1 219 ? 18.05629  -1.58502  -22.94357 1.000 16.06162  ?  300 ASN A ND2  1 
ATOM   3412 H H    A ASN A 1 219 ? 15.91264  -5.81240  -21.98562 1.000 12.47712  ?  300 ASN A H    1 
ATOM   3413 D D    B ASN A 1 219 ? 15.91162  -5.81302  -21.98332 0.000 12.47712  ?  300 ASN A D    1 
ATOM   3414 H HA   . ASN A 1 219 ? 15.36571  -3.02312  -22.84491 1.000 13.25837  ?  300 ASN A HA   1 
ATOM   3415 H HB2  . ASN A 1 219 ? 17.75055  -3.98187  -22.25541 1.000 13.83590  ?  300 ASN A HB2  1 
ATOM   3416 H HB3  . ASN A 1 219 ? 17.62767  -4.63410  -23.91325 1.000 13.83590  ?  300 ASN A HB3  1 
ATOM   3417 N N    . TYR A 1 220 ? 15.46464  -4.07085  -25.47329 1.000 10.81223  ?  301 TYR A N    1 
ATOM   3418 C CA   . TYR A 1 220 ? 14.65532  -4.17978  -26.68067 1.000 12.78185  ?  301 TYR A CA   1 
ATOM   3419 C C    . TYR A 1 220 ? 15.47012  -4.57013  -27.90680 1.000 10.77756  ?  301 TYR A C    1 
ATOM   3420 O O    . TYR A 1 220 ? 14.92149  -4.56262  -29.02587 1.000 12.52123  ?  301 TYR A O    1 
ATOM   3421 C CB   . TYR A 1 220 ? 13.92964  -2.82629  -26.98360 1.000 13.29016  ?  301 TYR A CB   1 
ATOM   3422 C CG   . TYR A 1 220 ? 13.18673  -2.18962  -25.80496 1.000 11.26103  ?  301 TYR A CG   1 
ATOM   3423 C CD1  . TYR A 1 220 ? 13.84154  -1.40165  -24.90036 1.000 12.93982  ?  301 TYR A CD1  1 
ATOM   3424 C CD2  . TYR A 1 220 ? 11.82302  -2.37734  -25.67921 1.000 12.04665  ?  301 TYR A CD2  1 
ATOM   3425 C CE1  . TYR A 1 220 ? 13.15752  -0.80723  -23.83401 1.000 12.85550  ?  301 TYR A CE1  1 
ATOM   3426 C CE2  . TYR A 1 220 ? 11.13129  -1.78882  -24.62225 1.000 12.22692  ?  301 TYR A CE2  1 
ATOM   3427 C CZ   . TYR A 1 220 ? 11.79972  -1.01930  -23.73494 1.000 14.52644  ?  301 TYR A CZ   1 
ATOM   3428 O OH   . TYR A 1 220 ? 11.09397  -0.40599  -22.71677 1.000 15.31449  ?  301 TYR A OH   1 
ATOM   3429 H H    A TYR A 1 220 ? 16.36749  -3.61706  -25.61228 0.691 12.97468  ?  301 TYR A H    1 
ATOM   3430 D D    B TYR A 1 220 ? 16.36729  -3.61694  -25.61322 0.309 12.97468  ?  301 TYR A D    1 
ATOM   3431 H HA   . TYR A 1 220 ? 13.90432  -4.95095  -26.50920 1.000 15.33822  ?  301 TYR A HA   1 
ATOM   3432 H HB2  . TYR A 1 220 ? 14.67566  -2.10700  -27.32149 1.000 15.94819  ?  301 TYR A HB2  1 
ATOM   3433 H HB3  . TYR A 1 220 ? 13.19645  -3.00072  -27.77108 1.000 15.94819  ?  301 TYR A HB3  1 
ATOM   3434 H HD1  . TYR A 1 220 ? 14.90297  -1.23521  -25.01018 1.000 15.52779  ?  301 TYR A HD1  1 
ATOM   3435 H HD2  . TYR A 1 220 ? 11.29291  -2.98091  -26.40108 1.000 14.45598  ?  301 TYR A HD2  1 
ATOM   3436 H HE1  . TYR A 1 220 ? 13.67906  -0.19956  -23.10935 1.000 15.42660  ?  301 TYR A HE1  1 
ATOM   3437 H HE2  . TYR A 1 220 ? 10.06848  -1.94659  -24.51300 1.000 14.67230  ?  301 TYR A HE2  1 
ATOM   3438 N N    . ASN A 1 221 ? 16.73484  -4.90157  -27.74892 1.000 11.26948  ?  302 ASN A N    1 
ATOM   3439 C CA   . ASN A 1 221 ? 17.57498  -5.18504  -28.89458 1.000 11.17119  ?  302 ASN A CA   1 
ATOM   3440 C C    . ASN A 1 221 ? 17.16749  -6.49099  -29.55116 1.000 11.79963  ?  302 ASN A C    1 
ATOM   3441 O O    . ASN A 1 221 ? 16.64366  -7.40574  -28.91396 1.000 12.26386  ?  302 ASN A O    1 
ATOM   3442 C CB   . ASN A 1 221 ? 19.02435  -5.35045  -28.48153 1.000 11.47861  ?  302 ASN A CB   1 
ATOM   3443 C CG   . ASN A 1 221 ? 19.65386  -4.08519  -27.93007 1.000 11.93717  ?  302 ASN A CG   1 
ATOM   3444 O OD1  . ASN A 1 221 ? 19.12581  -2.99007  -28.08683 1.000 13.23127  ?  302 ASN A OD1  1 
ATOM   3445 N ND2  . ASN A 1 221 ? 20.82919  -4.22216  -27.31981 1.000 12.36309  ?  302 ASN A ND2  1 
ATOM   3446 H H    A ASN A 1 221 ? 17.20660  -4.98259  -26.84821 0.597 13.52338  ?  302 ASN A H    1 
ATOM   3447 D D    B ASN A 1 221 ? 17.20781  -4.98294  -26.84887 0.403 13.52338  ?  302 ASN A D    1 
ATOM   3448 H HA   . ASN A 1 221 ? 17.47509  -4.35287  -29.59144 1.000 13.40543  ?  302 ASN A HA   1 
ATOM   3449 H HB2  . ASN A 1 221 ? 19.08281  -6.11490  -27.70675 1.000 13.77433  ?  302 ASN A HB2  1 
ATOM   3450 H HB3  . ASN A 1 221 ? 19.60400  -5.65703  -29.35223 1.000 13.77433  ?  302 ASN A HB3  1 
ATOM   3451 N N    . ALA A 1 222 ? 17.43143  -6.58784  -30.84485 1.000 11.92316  ?  303 ALA A N    1 
ATOM   3452 C CA   . ALA A 1 222 ? 17.25537  -7.85160  -31.52764 1.000 12.57857  ?  303 ALA A CA   1 
ATOM   3453 C C    . ALA A 1 222 ? 18.35139  -8.82803  -31.09749 1.000 11.88932  ?  303 ALA A C    1 
ATOM   3454 O O    . ALA A 1 222 ? 19.48342  -8.45098  -30.80614 1.000 12.00749  ?  303 ALA A O    1 
ATOM   3455 C CB   . ALA A 1 222 ? 17.33502  -7.64690  -33.04001 1.000 15.09616  ?  303 ALA A CB   1 
ATOM   3456 H H    A ALA A 1 222 ? 17.76186  -5.82348  -31.43389 0.712 14.30780  ?  303 ALA A H    1 
ATOM   3457 D D    B ALA A 1 222 ? 17.76188  -5.82434  -31.43500 0.288 14.30780  ?  303 ALA A D    1 
ATOM   3458 H HA   . ALA A 1 222 ? 16.28000  -8.27247  -31.28345 1.000 15.09429  ?  303 ALA A HA   1 
ATOM   3459 H HB1  . ALA A 1 222 ? 17.57624  -8.59803  -33.51463 1.000 18.11539  ?  303 ALA A HB1  1 
ATOM   3460 H HB2  . ALA A 1 222 ? 16.37194  -7.28535  -33.40039 1.000 18.11539  ?  303 ALA A HB2  1 
ATOM   3461 H HB3  . ALA A 1 222 ? 18.11235  -6.91472  -33.25857 1.000 18.11539  ?  303 ALA A HB3  1 
ATOM   3462 N N    . LEU A 1 223 ? 17.99596  -10.10856 -31.09975 1.000 11.85383  ?  304 LEU A N    1 
ATOM   3463 C CA   . LEU A 1 223 ? 19.02627  -11.13328 -31.05173 1.000 12.52829  ?  304 LEU A CA   1 
ATOM   3464 C C    . LEU A 1 223 ? 19.82669  -11.12457 -32.34978 1.000 14.28469  ?  304 LEU A C    1 
ATOM   3465 O O    . LEU A 1 223 ? 21.06056  -11.02193 -32.35260 1.000 13.98820  ?  304 LEU A O    1 
ATOM   3466 C CB   . LEU A 1 223 ? 18.41324  -12.51247 -30.79459 1.000 14.95731  ?  304 LEU A CB   1 
ATOM   3467 C CG   . LEU A 1 223 ? 19.36406  -13.70339 -30.78692 1.000 15.34493  ?  304 LEU A CG   1 
ATOM   3468 C CD1  . LEU A 1 223 ? 20.47876  -13.55661 -29.77579 1.000 17.63468  ?  304 LEU A CD1  1 
ATOM   3469 C CD2  . LEU A 1 223 ? 18.58788  -14.96928 -30.49896 1.000 19.82148  ?  304 LEU A CD2  1 
ATOM   3470 H H    A LEU A 1 223 ? 17.03728  -10.45531 -31.13305 0.662 14.22460  ?  304 LEU A H    1 
ATOM   3471 D D    B LEU A 1 223 ? 17.03807  -10.45749 -31.13300 0.338 14.22460  ?  304 LEU A D    1 
ATOM   3472 H HA   . LEU A 1 223 ? 19.69827  -10.92675 -30.21874 1.000 15.03395  ?  304 LEU A HA   1 
ATOM   3473 H HB2  . LEU A 1 223 ? 17.92834  -12.48698 -29.81872 1.000 17.94877  ?  304 LEU A HB2  1 
ATOM   3474 H HB3  . LEU A 1 223 ? 17.67423  -12.70115 -31.57328 1.000 17.94877  ?  304 LEU A HB3  1 
ATOM   3475 H HG   . LEU A 1 223 ? 19.83165  -13.76047 -31.76988 1.000 18.41391  ?  304 LEU A HG   1 
ATOM   3476 H HD11 . LEU A 1 223 ? 21.12754  -12.73509 -30.07959 1.000 21.16161  ?  304 LEU A HD11 1 
ATOM   3477 H HD12 . LEU A 1 223 ? 20.04549  -13.34604 -28.79802 1.000 21.16161  ?  304 LEU A HD12 1 
ATOM   3478 H HD13 . LEU A 1 223 ? 21.04805  -14.48536 -29.73788 1.000 21.16161  ?  304 LEU A HD13 1 
ATOM   3479 H HD21 . LEU A 1 223 ? 19.17873  -15.82805 -30.81757 1.000 23.78578  ?  304 LEU A HD21 1 
ATOM   3480 H HD22 . LEU A 1 223 ? 18.39182  -15.02957 -29.42844 1.000 23.78578  ?  304 LEU A HD22 1 
ATOM   3481 H HD23 . LEU A 1 223 ? 17.64679  -14.94121 -31.04820 1.000 23.78578  ?  304 LEU A HD23 1 
ATOM   3482 N N    . GLN A 1 224 ? 19.11918  -11.23269 -33.46867 1.000 15.51168  ?  305 GLN A N    1 
ATOM   3483 C CA   . GLN A 1 224 ? 19.74372  -11.27455 -34.79239 1.000 16.35618  ?  305 GLN A CA   1 
ATOM   3484 C C    . GLN A 1 224 ? 18.94031  -10.33103 -35.66718 1.000 17.66657  ?  305 GLN A C    1 
ATOM   3485 O O    . GLN A 1 224 ? 17.78666  -10.62391 -36.01487 1.000 22.54579  ?  305 GLN A O    1 
ATOM   3486 C CB   . GLN A 1 224 ? 19.73838  -12.69881 -35.32256 1.000 20.37258  ?  305 GLN A CB   1 
ATOM   3487 C CG   . GLN A 1 224 ? 20.51850  -12.83188 -36.61671 1.000 54.55994  ?  305 GLN A CG   1 
ATOM   3488 C CD   . GLN A 1 224 ? 21.13526  -14.19298 -36.77683 1.000 57.45527  ?  305 GLN A CD   1 
ATOM   3489 O OE1  . GLN A 1 224 ? 22.30509  -14.30926 -37.14044 1.000 62.30160  ?  305 GLN A OE1  1 
ATOM   3490 N NE2  . GLN A 1 224 ? 20.35359  -15.24249 -36.49836 1.000 58.59197  ?  305 GLN A NE2  1 
ATOM   3491 H H    A GLN A 1 224 ? 18.10135  -11.29413 -33.49409 0.708 18.61401  ?  305 GLN A H    1 
ATOM   3492 D D    B GLN A 1 224 ? 18.10129  -11.29400 -33.49195 0.292 18.61401  ?  305 GLN A D    1 
ATOM   3493 H HA   . GLN A 1 224 ? 20.77865  -10.93312 -34.77109 1.000 19.62742  ?  305 GLN A HA   1 
ATOM   3494 H HB2  . GLN A 1 224 ? 20.19290  -13.35712 -34.58218 1.000 24.44710  ?  305 GLN A HB2  1 
ATOM   3495 H HB3  . GLN A 1 224 ? 18.70973  -13.00529 -35.51242 1.000 24.44710  ?  305 GLN A HB3  1 
ATOM   3496 H HG2  . GLN A 1 224 ? 19.84565  -12.66393 -37.45764 1.000 65.47193  ?  305 GLN A HG2  1 
ATOM   3497 H HG3  . GLN A 1 224 ? 21.32018  -12.09344 -36.62745 1.000 65.47193  ?  305 GLN A HG3  1 
ATOM   3498 N N    . ALA A 1 225 ? 19.52199  -9.18152  -35.97620 1.000 17.39932  ?  306 ALA A N    1 
ATOM   3499 C CA   . ALA A 1 225 ? 18.82769  -8.16178  -36.76048 1.000 20.77926  ?  306 ALA A CA   1 
ATOM   3500 C C    . ALA A 1 225 ? 19.01368  -8.39306  -38.25282 1.000 23.66318  ?  306 ALA A C    1 
ATOM   3501 O O    . ALA A 1 225 ? 20.10274  -8.73350  -38.70844 1.000 22.61893  ?  306 ALA A O    1 
ATOM   3502 C CB   . ALA A 1 225 ? 19.38192  -6.77456  -36.42856 1.000 18.06412  ?  306 ALA A CB   1 
ATOM   3503 H H    A ALA A 1 225 ? 20.46974  -8.92372  -35.70103 0.651 20.87919  ?  306 ALA A H    1 
ATOM   3504 D D    B ALA A 1 225 ? 20.46981  -8.92435  -35.70069 0.349 20.87919  ?  306 ALA A D    1 
ATOM   3505 H HA   . ALA A 1 225 ? 17.76477  -8.21185  -36.52424 1.000 24.93511  ?  306 ALA A HA   1 
ATOM   3506 H HB1  . ALA A 1 225 ? 18.62434  -6.02538  -36.65858 1.000 21.67694  ?  306 ALA A HB1  1 
ATOM   3507 H HB2  . ALA A 1 225 ? 19.63219  -6.73676  -35.36836 1.000 21.67694  ?  306 ALA A HB2  1 
ATOM   3508 H HB3  . ALA A 1 225 ? 20.27481  -6.59644  -37.02783 1.000 21.67694  ?  306 ALA A HB3  1 
ATOM   3509 N N    . ALA A 1 226 ? 17.93665  -8.16896  -39.00608 1.000 26.96607  ?  307 ALA A N    1 
ATOM   3510 C CA   . ALA A 1 226 ? 18.01132  -8.22407  -40.46580 1.000 36.94999  ?  307 ALA A CA   1 
ATOM   3511 C C    . ALA A 1 226 ? 18.98067  -7.17506  -40.99898 1.000 31.54192  ?  307 ALA A C    1 
ATOM   3512 O O    . ALA A 1 226 ? 19.87595  -7.47882  -41.80144 1.000 38.38258  ?  307 ALA A O    1 
ATOM   3513 C CB   . ALA A 1 226 ? 16.60814  -7.97779  -41.04049 1.000 29.94957  ?  307 ALA A CB   1 
ATOM   3514 H H    A ALA A 1 226 ? 17.00940  -7.94952  -38.64215 0.703 32.35929  ?  307 ALA A H    1 
ATOM   3515 D D    B ALA A 1 226 ? 17.00855  -7.94939  -38.64439 0.297 32.35929  ?  307 ALA A D    1 
ATOM   3516 H HA   . ALA A 1 226 ? 18.36397  -9.20752  -40.77655 1.000 44.33999  ?  307 ALA A HA   1 
ATOM   3517 H HB1  . ALA A 1 226 ? 16.33271  -6.93695  -40.87051 1.000 35.93949  ?  307 ALA A HB1  1 
ATOM   3518 H HB2  . ALA A 1 226 ? 16.62045  -8.18917  -42.10972 1.000 35.93949  ?  307 ALA A HB2  1 
ATOM   3519 H HB3  . ALA A 1 226 ? 15.89882  -8.63656  -40.53950 1.000 35.93949  ?  307 ALA A HB3  1 
ATOM   3520 N N    . SER A 1 227 ? 18.81391  -5.93017  -40.55763 1.000 26.88458  ?  308 SER A N    1 
ATOM   3521 C CA   . SER A 1 227 ? 19.73020  -4.83852  -40.84972 1.000 24.89811  ?  308 SER A CA   1 
ATOM   3522 C C    . SER A 1 227 ? 19.85736  -4.00919  -39.57980 1.000 19.38932  ?  308 SER A C    1 
ATOM   3523 O O    . SER A 1 227 ? 18.94510  -4.01933  -38.73597 1.000 21.73381  ?  308 SER A O    1 
ATOM   3524 C CB   . SER A 1 227 ? 19.20625  -3.93462  -41.97875 1.000 26.43665  ?  308 SER A CB   1 
ATOM   3525 O OG   . SER A 1 227 ? 17.94903  -3.40096  -41.63779 1.000 35.59918  ?  308 SER A OG   1 
ATOM   3526 H H    A SER A 1 227 ? 18.02652  -5.64188  -39.97686 0.481 32.26150  ?  308 SER A H    1 
ATOM   3527 D D    B SER A 1 227 ? 18.02571  -5.64401  -39.97691 0.519 32.26150  ?  308 SER A D    1 
ATOM   3528 H HA   . SER A 1 227 ? 20.70277  -5.22686  -41.15203 1.000 29.87773  ?  308 SER A HA   1 
ATOM   3529 H HB2  . SER A 1 227 ? 19.90975  -3.11716  -42.13668 1.000 31.72398  ?  308 SER A HB2  1 
ATOM   3530 H HB3  . SER A 1 227 ? 19.10827  -4.52357  -42.89069 1.000 31.72398  ?  308 SER A HB3  1 
ATOM   3531 N N    . PRO A 1 228 ? 20.98072  -3.32152  -39.40231 1.000 19.63773  ?  309 PRO A N    1 
ATOM   3532 C CA   . PRO A 1 228 ? 21.21251  -2.56996  -38.15936 1.000 18.78644  ?  309 PRO A CA   1 
ATOM   3533 C C    . PRO A 1 228 ? 20.16059  -1.50225  -37.91384 1.000 20.56291  ?  309 PRO A C    1 
ATOM   3534 O O    . PRO A 1 228 ? 19.75465  -0.76834  -38.81014 1.000 19.61744  ?  309 PRO A O    1 
ATOM   3535 C CB   . PRO A 1 228 ? 22.59588  -1.91911  -38.38670 1.000 17.98799  ?  309 PRO A CB   1 
ATOM   3536 C CG   . PRO A 1 228 ? 23.26580  -2.80301  -39.35656 1.000 25.64394  ?  309 PRO A CG   1 
ATOM   3537 C CD   . PRO A 1 228 ? 22.19251  -3.35363  -40.25515 1.000 21.89587  ?  309 PRO A CD   1 
ATOM   3538 H HA   . PRO A 1 228 ? 21.23668  -3.26106  -37.31681 1.000 22.54373  ?  309 PRO A HA   1 
ATOM   3539 H HB2  . PRO A 1 228 ? 22.47351  -0.91447  -38.79143 1.000 21.58559  ?  309 PRO A HB2  1 
ATOM   3540 H HB3  . PRO A 1 228 ? 23.14769  -1.87804  -37.44759 1.000 21.58559  ?  309 PRO A HB3  1 
ATOM   3541 H HG2  . PRO A 1 228 ? 23.98932  -2.22720  -39.93367 1.000 30.77273  ?  309 PRO A HG2  1 
ATOM   3542 H HG3  . PRO A 1 228 ? 23.77031  -3.60980  -38.82490 1.000 30.77273  ?  309 PRO A HG3  1 
ATOM   3543 H HD2  . PRO A 1 228 ? 22.06354  -2.72404  -41.13554 1.000 26.27504  ?  309 PRO A HD2  1 
ATOM   3544 H HD3  . PRO A 1 228 ? 22.42644  -4.37431  -40.55778 1.000 26.27504  ?  309 PRO A HD3  1 
ATOM   3545 N N    . ASP A 1 229 ? 19.68357  -1.44813  -36.67893 1.000 17.21369  ?  310 ASP A N    1 
ATOM   3546 C CA   . ASP A 1 229 ? 18.86046  -0.33411  -36.23692 1.000 16.98669  ?  310 ASP A CA   1 
ATOM   3547 C C    . ASP A 1 229 ? 19.68584  0.94437   -36.31084 1.000 18.10192  ?  310 ASP A C    1 
ATOM   3548 O O    . ASP A 1 229 ? 20.84115  0.95368   -35.91427 1.000 15.88904  ?  310 ASP A O    1 
ATOM   3549 C CB   . ASP A 1 229 ? 18.45085  -0.62992  -34.78408 1.000 15.01587  ?  310 ASP A CB   1 
ATOM   3550 C CG   . ASP A 1 229 ? 17.38104  0.28182   -34.25120 1.000 19.06338  ?  310 ASP A CG   1 
ATOM   3551 O OD1  . ASP A 1 229 ? 17.41963  1.50620   -34.50959 1.000 18.68725  ?  310 ASP A OD1  1 
ATOM   3552 O OD2  . ASP A 1 229 ? 16.46410  -0.21487  -33.54527 1.000 17.95101  -1 310 ASP A OD2  1 
ATOM   3553 H H    A ASP A 1 229 ? 19.84739  -2.15578  -35.96284 0.846 20.65643  ?  310 ASP A H    1 
ATOM   3554 D D    B ASP A 1 229 ? 19.84602  -2.15445  -35.96122 0.154 20.65643  ?  310 ASP A D    1 
ATOM   3555 H HA   . ASP A 1 229 ? 17.97252  -0.19433  -36.85346 1.000 20.38402  ?  310 ASP A HA   1 
ATOM   3556 H HB2  . ASP A 1 229 ? 18.07330  -1.65092  -34.72831 1.000 18.01904  ?  310 ASP A HB2  1 
ATOM   3557 H HB3  . ASP A 1 229 ? 19.32694  -0.52097  -34.14480 1.000 18.01904  ?  310 ASP A HB3  1 
ATOM   3558 N N    . PRO A 1 230 ? 19.12609  2.04020   -36.85491 1.000 18.66631  ?  311 PRO A N    1 
ATOM   3559 C CA   . PRO A 1 230 ? 19.90878  3.26975   -36.98337 1.000 18.53716  ?  311 PRO A CA   1 
ATOM   3560 C C    . PRO A 1 230 ? 20.54270  3.77161   -35.70483 1.000 17.06652  ?  311 PRO A C    1 
ATOM   3561 O O    . PRO A 1 230 ? 21.57766  4.44360   -35.75834 1.000 20.07572  ?  311 PRO A O    1 
ATOM   3562 C CB   . PRO A 1 230 ? 18.88150  4.30702   -37.47901 1.000 22.15762  ?  311 PRO A CB   1 
ATOM   3563 C CG   . PRO A 1 230 ? 17.75760  3.55447   -38.00720 1.000 25.86887  ?  311 PRO A CG   1 
ATOM   3564 C CD   . PRO A 1 230 ? 17.75677  2.17968   -37.40213 1.000 26.69668  ?  311 PRO A CD   1 
ATOM   3565 H HA   . PRO A 1 230 ? 20.67991  3.08723   -37.73180 1.000 22.24459  ?  311 PRO A HA   1 
ATOM   3566 H HB2  . PRO A 1 230 ? 18.56581  4.93398   -36.64512 1.000 26.58914  ?  311 PRO A HB2  1 
ATOM   3567 H HB3  . PRO A 1 230 ? 19.33192  4.92197   -38.25815 1.000 26.58914  ?  311 PRO A HB3  1 
ATOM   3568 H HG2  . PRO A 1 230 ? 16.83426  4.07427   -37.75152 1.000 31.04265  ?  311 PRO A HG2  1 
ATOM   3569 H HG3  . PRO A 1 230 ? 17.85836  3.48445   -39.09027 1.000 31.04265  ?  311 PRO A HG3  1 
ATOM   3570 H HD2  . PRO A 1 230 ? 17.01363  2.10702   -36.60805 1.000 32.03601  ?  311 PRO A HD2  1 
ATOM   3571 H HD3  . PRO A 1 230 ? 17.56512  1.42256   -38.16249 1.000 32.03601  ?  311 PRO A HD3  1 
ATOM   3572 N N    . ILE A 1 231 ? 19.92735  3.48985   -34.53281 1.000 17.66436  ?  312 ILE A N    1 
ATOM   3573 C CA   . ILE A 1 231 ? 20.49216  3.94446   -33.25067 1.000 16.77763  ?  312 ILE A CA   1 
ATOM   3574 C C    . ILE A 1 231 ? 21.86049  3.32972   -32.96440 1.000 14.02119  ?  312 ILE A C    1 
ATOM   3575 O O    . ILE A 1 231 ? 22.57495  3.80679   -32.08977 1.000 15.76393  ?  312 ILE A O    1 
ATOM   3576 C CB   . ILE A 1 231 ? 19.54471  3.65465   -32.05207 1.000 18.24563  ?  312 ILE A CB   1 
ATOM   3577 C CG1  . ILE A 1 231 ? 19.44302  2.11358   -31.86272 1.000 19.69144  ?  312 ILE A CG1  1 
ATOM   3578 C CG2  . ILE A 1 231 ? 18.20132  4.35850   -32.25982 1.000 18.91782  ?  312 ILE A CG2  1 
ATOM   3579 C CD1  . ILE A 1 231 ? 18.40632  1.67689   -30.88294 1.000 21.86476  ?  312 ILE A CD1  1 
ATOM   3580 H H    A ILE A 1 231 ? 19.05893  2.96195   -34.44582 0.731 21.19723  ?  312 ILE A H    1 
ATOM   3581 D D    B ILE A 1 231 ? 19.05898  2.96212   -34.44424 0.269 21.19723  ?  312 ILE A D    1 
ATOM   3582 H HA   . ILE A 1 231 ? 20.59833  5.02501   -33.34675 1.000 20.13315  ?  312 ILE A HA   1 
ATOM   3583 H HB   . ILE A 1 231 ? 19.94346  4.06281   -31.12336 1.000 21.89476  ?  312 ILE A HB   1 
ATOM   3584 H HG12 . ILE A 1 231 ? 19.19859  1.66119   -32.82381 1.000 23.62973  ?  312 ILE A HG12 1 
ATOM   3585 H HG13 . ILE A 1 231 ? 20.40557  1.74294   -31.51026 1.000 23.62973  ?  312 ILE A HG13 1 
ATOM   3586 H HG21 . ILE A 1 231 ? 18.04867  4.52418   -33.32628 1.000 22.70138  ?  312 ILE A HG21 1 
ATOM   3587 H HG22 . ILE A 1 231 ? 17.40530  3.72783   -31.86396 1.000 22.70138  ?  312 ILE A HG22 1 
ATOM   3588 H HG23 . ILE A 1 231 ? 18.21569  5.31301   -31.73369 1.000 22.70138  ?  312 ILE A HG23 1 
ATOM   3589 H HD11 . ILE A 1 231 ? 18.01236  2.55354   -30.36876 1.000 26.23771  ?  312 ILE A HD11 1 
ATOM   3590 H HD12 . ILE A 1 231 ? 17.60440  1.16812   -31.41790 1.000 26.23771  ?  312 ILE A HD12 1 
ATOM   3591 H HD13 . ILE A 1 231 ? 18.86236  0.99737   -30.16295 1.000 26.23771  ?  312 ILE A HD13 1 
ATOM   3592 N N    . THR A 1 232 ? 22.25483  2.28636   -33.70310 1.000 13.97404  ?  313 THR A N    1 
ATOM   3593 C CA   . THR A 1 232 ? 23.49197  1.56699   -33.40719 1.000 15.09734  ?  313 THR A CA   1 
ATOM   3594 C C    . THR A 1 232 ? 24.70315  2.08743   -34.15916 1.000 15.73701  ?  313 THR A C    1 
ATOM   3595 O O    . THR A 1 232 ? 25.76526  1.50032   -34.04608 1.000 15.60291  ?  313 THR A O    1 
ATOM   3596 C CB   . THR A 1 232 ? 23.36946  0.07092   -33.72908 1.000 14.29459  ?  313 THR A CB   1 
ATOM   3597 O OG1  . THR A 1 232 ? 23.18101  -0.14613  -35.14447 1.000 16.08132  ?  313 THR A OG1  1 
ATOM   3598 C CG2  . THR A 1 232 ? 22.16318  -0.55148  -33.00966 1.000 14.27125  ?  313 THR A CG2  1 
ATOM   3599 H H    A THR A 1 232 ? 21.74041  1.92208   -34.50502 0.715 16.76884  ?  313 THR A H    1 
ATOM   3600 D D    B THR A 1 232 ? 21.73954  1.92295   -34.50485 0.285 16.76884  ?  313 THR A D    1 
ATOM   3601 H HA   . THR A 1 232 ? 23.65563  1.68509   -32.33603 1.000 18.11681  ?  313 THR A HA   1 
ATOM   3602 H HB   . THR A 1 232 ? 24.29065  -0.40861  -33.39808 1.000 17.15351  ?  313 THR A HB   1 
ATOM   3603 H HG21 . THR A 1 232 ? 22.24022  -0.37994  -31.93600 1.000 17.12550  ?  313 THR A HG21 1 
ATOM   3604 H HG22 . THR A 1 232 ? 21.23929  -0.10246  -33.37423 1.000 17.12550  ?  313 THR A HG22 1 
ATOM   3605 H HG23 . THR A 1 232 ? 22.13184  -1.62515  -33.19500 1.000 17.12550  ?  313 THR A HG23 1 
ATOM   3606 N N    . GLN A 1 233 ? 24.56370  3.13637   -34.96863 1.000 15.50768  ?  314 GLN A N    1 
ATOM   3607 C CA   . GLN A 1 233 ? 25.67659  3.56108   -35.81581 1.000 16.14262  ?  314 GLN A CA   1 
ATOM   3608 C C    . GLN A 1 233 ? 26.91601  3.78922   -34.99816 1.000 15.29591  ?  314 GLN A C    1 
ATOM   3609 O O    . GLN A 1 233 ? 26.87068  4.42412   -33.95785 1.000 15.66446  ?  314 GLN A O    1 
ATOM   3610 C CB   . GLN A 1 233 ? 25.37028  4.86043   -36.53886 1.000 20.12479  ?  314 GLN A CB   1 
ATOM   3611 C CG   . GLN A 1 233 ? 24.43189  4.68693   -37.69618 1.000 40.50164  ?  314 GLN A CG   1 
ATOM   3612 C CD   . GLN A 1 233 ? 24.08846  6.02148   -38.30160 1.000 42.94288  ?  314 GLN A CD   1 
ATOM   3613 O OE1  . GLN A 1 233 ? 24.84749  6.55794   -39.11350 1.000 55.91981  ?  314 GLN A OE1  1 
ATOM   3614 N NE2  . GLN A 1 233 ? 22.95924  6.58446   -37.88287 1.000 51.14655  ?  314 GLN A NE2  1 
ATOM   3615 H H    A GLN A 1 233 ? 23.71686  3.69774   -35.05882 0.781 18.60922  ?  314 GLN A H    1 
ATOM   3616 D D    B GLN A 1 233 ? 23.71753  3.69859   -35.05982 0.219 18.60922  ?  314 GLN A D    1 
ATOM   3617 H HA   . GLN A 1 233 ? 25.83902  2.77141   -36.54939 1.000 19.37114  ?  314 GLN A HA   1 
ATOM   3618 H HB2  . GLN A 1 233 ? 24.91071  5.55524   -35.83590 1.000 24.14975  ?  314 GLN A HB2  1 
ATOM   3619 H HB3  . GLN A 1 233 ? 26.30112  5.27873   -36.92183 1.000 24.14975  ?  314 GLN A HB3  1 
ATOM   3620 H HG2  . GLN A 1 233 ? 24.90502  4.07002   -38.46016 1.000 48.60196  ?  314 GLN A HG2  1 
ATOM   3621 H HG3  . GLN A 1 233 ? 23.51195  4.21415   -37.35223 1.000 48.60196  ?  314 GLN A HG3  1 
ATOM   3622 N N    . GLY A 1 234 ? 28.05215  3.28262   -35.50142 1.000 16.63075  ?  315 GLY A N    1 
ATOM   3623 C CA   . GLY A 1 234 ? 29.31216  3.35771   -34.83916 1.000 14.76118  ?  315 GLY A CA   1 
ATOM   3624 C C    . GLY A 1 234 ? 29.71043  2.08339   -34.11576 1.000 14.90073  ?  315 GLY A C    1 
ATOM   3625 O O    . GLY A 1 234 ? 30.87236  1.90974   -33.80986 1.000 16.29271  ?  315 GLY A O    1 
ATOM   3626 H H    A GLY A 1 234 ? 28.10341  2.80266   -36.39998 0.736 19.95690  ?  315 GLY A H    1 
ATOM   3627 D D    B GLY A 1 234 ? 28.10126  2.80297   -36.40026 0.264 19.95690  ?  315 GLY A D    1 
ATOM   3628 H HA2  . GLY A 1 234 ? 30.08435  3.58126   -35.57527 1.000 17.71342  ?  315 GLY A HA2  1 
ATOM   3629 H HA3  . GLY A 1 234 ? 29.27725  4.16325   -34.10568 1.000 17.71342  ?  315 GLY A HA3  1 
ATOM   3630 N N    . ASN A 1 235 ? 28.74405  1.21995   -33.79733 1.000 15.19179  ?  316 ASN A N    1 
ATOM   3631 C CA   . ASN A 1 235 ? 29.00711  -0.03271  -33.08787 1.000 15.25631  ?  316 ASN A CA   1 
ATOM   3632 C C    . ASN A 1 235 ? 28.84054  -1.19528  -34.04027 1.000 13.05330  ?  316 ASN A C    1 
ATOM   3633 O O    . ASN A 1 235 ? 27.71892  -1.45886  -34.48173 1.000 14.80637  ?  316 ASN A O    1 
ATOM   3634 C CB   . ASN A 1 235 ? 28.02916  -0.18083  -31.90991 1.000 13.87032  ?  316 ASN A CB   1 
ATOM   3635 C CG   . ASN A 1 235 ? 28.39736  -1.31305  -31.01153 1.000 14.46135  ?  316 ASN A CG   1 
ATOM   3636 O OD1  . ASN A 1 235 ? 29.17640  -2.15100  -31.34309 1.000 14.19819  ?  316 ASN A OD1  1 
ATOM   3637 N ND2  . ASN A 1 235 ? 27.78516  -1.33640  -29.82719 1.000 15.58766  ?  316 ASN A ND2  1 
ATOM   3638 H H    A ASN A 1 235 ? 27.75872  1.36170   -34.01964 0.593 18.23015  ?  316 ASN A H    1 
ATOM   3639 D D    B ASN A 1 235 ? 27.75887  1.36229   -34.01993 0.407 18.23015  ?  316 ASN A D    1 
ATOM   3640 H HA   . ASN A 1 235 ? 30.02972  -0.03143  -32.71056 1.000 18.30757  ?  316 ASN A HA   1 
ATOM   3641 H HB2  . ASN A 1 235 ? 28.03676  0.73645   -31.32115 1.000 16.64439  ?  316 ASN A HB2  1 
ATOM   3642 H HB3  . ASN A 1 235 ? 27.02756  -0.36662  -32.29771 1.000 16.64439  ?  316 ASN A HB3  1 
ATOM   3643 N N    . PRO A 1 236 ? 29.90874  -1.93225  -34.36592 1.000 15.88158  ?  317 PRO A N    1 
ATOM   3644 C CA   . PRO A 1 236 ? 29.73117  -3.11290  -35.23005 1.000 16.52841  ?  317 PRO A CA   1 
ATOM   3645 C C    . PRO A 1 236 ? 28.91328  -4.20959  -34.59636 1.000 15.97182  ?  317 PRO A C    1 
ATOM   3646 O O    . PRO A 1 236 ? 28.40737  -5.08479  -35.29950 1.000 18.08585  ?  317 PRO A O    1 
ATOM   3647 C CB   . PRO A 1 236 ? 31.16739  -3.59898  -35.47733 1.000 17.64169  ?  317 PRO A CB   1 
ATOM   3648 C CG   . PRO A 1 236 ? 31.97514  -3.00953  -34.41483 1.000 21.86634  ?  317 PRO A CG   1 
ATOM   3649 C CD   . PRO A 1 236 ? 31.31746  -1.74058  -33.97091 1.000 15.48727  ?  317 PRO A CD   1 
ATOM   3650 H HA   . PRO A 1 236 ? 29.27602  -2.80498  -36.17140 1.000 19.83409  ?  317 PRO A HA   1 
ATOM   3651 H HB2  . PRO A 1 236 ? 31.20010  -4.68743  -35.42941 1.000 21.17003  ?  317 PRO A HB2  1 
ATOM   3652 H HB3  . PRO A 1 236 ? 31.50705  -3.25851  -36.45550 1.000 21.17003  ?  317 PRO A HB3  1 
ATOM   3653 H HG2  . PRO A 1 236 ? 32.03655  -3.71154  -33.58325 1.000 26.23961  ?  317 PRO A HG2  1 
ATOM   3654 H HG3  . PRO A 1 236 ? 32.97291  -2.80037  -34.80060 1.000 26.23961  ?  317 PRO A HG3  1 
ATOM   3655 H HD2  . PRO A 1 236 ? 31.40416  -1.61572  -32.89157 1.000 18.58473  ?  317 PRO A HD2  1 
ATOM   3656 H HD3  . PRO A 1 236 ? 31.74995  -0.88024  -34.48166 1.000 18.58473  ?  317 PRO A HD3  1 
ATOM   3657 N N    . ASN A 1 237 ? 28.73801  -4.16766  -33.27966 1.000 14.42910  ?  318 ASN A N    1 
ATOM   3658 C CA   . ASN A 1 237 ? 27.96187  -5.17650  -32.52940 1.000 14.05242  ?  318 ASN A CA   1 
ATOM   3659 C C    . ASN A 1 237 ? 26.55366  -4.64261  -32.31487 1.000 12.85404  ?  318 ASN A C    1 
ATOM   3660 O O    . ASN A 1 237 ? 26.20649  -4.17657  -31.23646 1.000 14.95860  ?  318 ASN A O    1 
ATOM   3661 C CB   . ASN A 1 237 ? 28.71777  -5.51172  -31.27715 1.000 14.67245  ?  318 ASN A CB   1 
ATOM   3662 C CG   . ASN A 1 237 ? 30.03588  -6.21252  -31.57608 1.000 16.09065  ?  318 ASN A CG   1 
ATOM   3663 O OD1  . ASN A 1 237 ? 30.12692  -6.94287  -32.57669 1.000 16.44673  ?  318 ASN A OD1  1 
ATOM   3664 N ND2  . ASN A 1 237 ? 31.03956  -5.99431  -30.75227 1.000 19.06715  ?  318 ASN A ND2  1 
ATOM   3665 H H    A ASN A 1 237 ? 29.12473  -3.43671  -32.68252 1.000 17.31492  ?  318 ASN A H    1 
ATOM   3666 D D    B ASN A 1 237 ? 29.12528  -3.43612  -32.68361 0.000 17.31492  ?  318 ASN A D    1 
ATOM   3667 H HA   . ASN A 1 237 ? 27.83226  -6.09691  -33.09875 1.000 16.86290  ?  318 ASN A HA   1 
ATOM   3668 H HB2  . ASN A 1 237 ? 28.93644  -4.59253  -30.73367 1.000 17.60694  ?  318 ASN A HB2  1 
ATOM   3669 H HB3  . ASN A 1 237 ? 28.11198  -6.17483  -30.65957 1.000 17.60694  ?  318 ASN A HB3  1 
ATOM   3670 N N    . TYR A 1 238 ? 25.73580  -4.68536  -33.38521 1.000 13.49007  ?  319 TYR A N    1 
ATOM   3671 C CA   . TYR A 1 238 ? 24.47585  -3.98663  -33.41807 1.000 12.93975  ?  319 TYR A CA   1 
ATOM   3672 C C    . TYR A 1 238 ? 23.31110  -4.82807  -32.92743 1.000 14.66705  ?  319 TYR A C    1 
ATOM   3673 O O    . TYR A 1 238 ? 22.17519  -4.33141  -32.88746 1.000 14.77290  ?  319 TYR A O    1 
ATOM   3674 C CB   . TYR A 1 238 ? 24.19487  -3.48846  -34.83594 1.000 15.03194  ?  319 TYR A CB   1 
ATOM   3675 C CG   . TYR A 1 238 ? 24.32666  -4.52581  -35.93189 1.000 14.80609  ?  319 TYR A CG   1 
ATOM   3676 C CD1  . TYR A 1 238 ? 23.29302  -5.39763  -36.22585 1.000 16.43273  ?  319 TYR A CD1  1 
ATOM   3677 C CD2  . TYR A 1 238 ? 25.48908  -4.59178  -36.69458 1.000 16.76222  ?  319 TYR A CD2  1 
ATOM   3678 C CE1  . TYR A 1 238 ? 23.41488  -6.36245  -37.23589 1.000 18.53913  ?  319 TYR A CE1  1 
ATOM   3679 C CE2  . TYR A 1 238 ? 25.60885  -5.56482  -37.71279 1.000 18.67488  ?  319 TYR A CE2  1 
ATOM   3680 C CZ   . TYR A 1 238 ? 24.58567  -6.41771  -37.95597 1.000 21.35919  ?  319 TYR A CZ   1 
ATOM   3681 O OH   . TYR A 1 238 ? 24.69199  -7.37114  -38.96192 1.000 25.09280  ?  319 TYR A OH   1 
ATOM   3682 H H    A TYR A 1 238 ? 25.93983  -5.20494  -34.23891 1.000 16.18809  ?  319 TYR A H    1 
ATOM   3683 D D    B TYR A 1 238 ? 25.94092  -5.20532  -34.23842 0.000 16.18809  ?  319 TYR A D    1 
ATOM   3684 H HA   . TYR A 1 238 ? 24.54437  -3.11740  -32.76398 1.000 15.52770  ?  319 TYR A HA   1 
ATOM   3685 H HB2  . TYR A 1 238 ? 23.17338  -3.10963  -34.86967 1.000 18.03833  ?  319 TYR A HB2  1 
ATOM   3686 H HB3  . TYR A 1 238 ? 24.89753  -2.68662  -35.06272 1.000 18.03833  ?  319 TYR A HB3  1 
ATOM   3687 H HD1  . TYR A 1 238 ? 22.37230  -5.33348  -35.66501 1.000 19.71928  ?  319 TYR A HD1  1 
ATOM   3688 H HD2  . TYR A 1 238 ? 26.29802  -3.90079  -36.50875 1.000 20.11466  ?  319 TYR A HD2  1 
ATOM   3689 H HE1  . TYR A 1 238 ? 22.60660  -7.04780  -37.44416 1.000 22.24696  ?  319 TYR A HE1  1 
ATOM   3690 H HE2  . TYR A 1 238 ? 26.51551  -5.62797  -38.29621 1.000 22.40986  ?  319 TYR A HE2  1 
ATOM   3691 N N    . ASP A 1 239 ? 23.55368  -6.07924  -32.56236 1.000 12.24157  ?  320 ASP A N    1 
ATOM   3692 C CA   . ASP A 1 239 ? 22.51562  -6.94661  -32.00664 1.000 12.57037  ?  320 ASP A CA   1 
ATOM   3693 C C    . ASP A 1 239 ? 23.18122  -7.84348  -30.96605 1.000 13.19417  ?  320 ASP A C    1 
ATOM   3694 O O    . ASP A 1 239 ? 24.40799  -7.84848  -30.78935 1.000 12.16372  ?  320 ASP A O    1 
ATOM   3695 C CB   . ASP A 1 239 ? 21.75172  -7.70243  -33.09439 1.000 13.25892  ?  320 ASP A CB   1 
ATOM   3696 C CG   . ASP A 1 239 ? 22.64792  -8.53018  -33.98965 1.000 14.69935  ?  320 ASP A CG   1 
ATOM   3697 O OD1  . ASP A 1 239 ? 23.78621  -8.85294  -33.58143 1.000 15.07727  ?  320 ASP A OD1  1 
ATOM   3698 O OD2  . ASP A 1 239 ? 22.15947  -8.88708  -35.09626 1.000 16.60710  -1 320 ASP A OD2  1 
ATOM   3699 H H    A ASP A 1 239 ? 24.46582  -6.52946  -32.63794 0.880 14.68989  ?  320 ASP A H    1 
ATOM   3700 D D    B ASP A 1 239 ? 24.46594  -6.52919  -32.63806 0.120 14.68989  ?  320 ASP A D    1 
ATOM   3701 H HA   . ASP A 1 239 ? 21.75579  -6.36229  -31.48767 1.000 15.08445  ?  320 ASP A HA   1 
ATOM   3702 H HB2  . ASP A 1 239 ? 21.03767  -8.37621  -32.62083 1.000 15.91071  ?  320 ASP A HB2  1 
ATOM   3703 H HB3  . ASP A 1 239 ? 21.22567  -6.98245  -33.72130 1.000 15.91071  ?  320 ASP A HB3  1 
ATOM   3704 N N    . GLU A 1 240 ? 22.35064  -8.62384  -30.26862 1.000 11.70375  ?  321 GLU A N    1 
ATOM   3705 C CA   . GLU A 1 240 ? 22.89772  -9.40148  -29.14800 1.000 11.31073  ?  321 GLU A CA   1 
ATOM   3706 C C    . GLU A 1 240 ? 23.79909  -10.53330 -29.64428 1.000 10.45657  ?  321 GLU A C    1 
ATOM   3707 O O    . GLU A 1 240 ? 24.76930  -10.87398 -28.97875 1.000 11.33190  ?  321 GLU A O    1 
ATOM   3708 C CB   . GLU A 1 240 ? 21.78912  -9.91612  -28.26696 1.000 11.15059  ?  321 GLU A CB   1 
ATOM   3709 C CG   . GLU A 1 240 ? 21.02175  -8.79187  -27.54480 1.000 9.63794   ?  321 GLU A CG   1 
ATOM   3710 C CD   . GLU A 1 240 ? 21.87861  -7.92947  -26.67255 1.000 11.75522  ?  321 GLU A CD   1 
ATOM   3711 O OE1  . GLU A 1 240 ? 22.47375  -8.45285  -25.72492 1.000 13.73859  ?  321 GLU A OE1  1 
ATOM   3712 O OE2  . GLU A 1 240 ? 22.05583  -6.74433  -26.99105 1.000 12.87203  -1 321 GLU A OE2  1 
ATOM   3713 H H    A GLU A 1 240 ? 21.35160  -8.73545  -30.44141 0.931 14.04451  ?  321 GLU A H    1 
ATOM   3714 D D    B GLU A 1 240 ? 21.35145  -8.73707  -30.43948 0.069 14.04451  ?  321 GLU A D    1 
ATOM   3715 H HA   . GLU A 1 240 ? 23.50828  -8.74786  -28.52503 1.000 13.57288  ?  321 GLU A HA   1 
ATOM   3716 H HB2  . GLU A 1 240 ? 21.07749  -10.46856 -28.88055 1.000 13.38071  ?  321 GLU A HB2  1 
ATOM   3717 H HB3  . GLU A 1 240 ? 22.21602  -10.57261 -27.50875 1.000 13.38071  ?  321 GLU A HB3  1 
ATOM   3718 H HG2  . GLU A 1 240 ? 20.55871  -8.14854  -28.29301 1.000 11.56553  ?  321 GLU A HG2  1 
ATOM   3719 H HG3  . GLU A 1 240 ? 20.25505  -9.24164  -26.91395 1.000 11.56553  ?  321 GLU A HG3  1 
ATOM   3720 N N    . ILE A 1 241 ? 23.51282  -11.13173 -30.81756 1.000 12.74060  ?  322 ILE A N    1 
ATOM   3721 C CA   . ILE A 1 241 ? 24.37682  -12.23673 -31.25926 1.000 11.97810  ?  322 ILE A CA   1 
ATOM   3722 C C    . ILE A 1 241 ? 25.77609  -11.73239 -31.57236 1.000 11.51076  ?  322 ILE A C    1 
ATOM   3723 O O    . ILE A 1 241 ? 26.76805  -12.39987 -31.30388 1.000 12.70444  ?  322 ILE A O    1 
ATOM   3724 C CB   . ILE A 1 241 ? 23.72923  -13.00881 -32.41052 1.000 14.08543  ?  322 ILE A CB   1 
ATOM   3725 C CG1  . ILE A 1 241 ? 24.48852  -14.30230 -32.65735 1.000 18.45047  ?  322 ILE A CG1  1 
ATOM   3726 C CG2  . ILE A 1 241 ? 23.70667  -12.20828 -33.68352 1.000 17.17038  ?  322 ILE A CG2  1 
ATOM   3727 C CD1  . ILE A 1 241 ? 24.32807  -15.30366 -31.58460 1.000 25.22536  ?  322 ILE A CD1  1 
ATOM   3728 H H    A ILE A 1 241 ? 22.74214  -10.88911 -31.44012 0.887 15.28872  ?  322 ILE A H    1 
ATOM   3729 D D    B ILE A 1 241 ? 22.74279  -10.89077 -31.44158 0.113 15.28872  ?  322 ILE A D    1 
ATOM   3730 H HA   . ILE A 1 241 ? 24.48108  -12.94770 -30.43966 1.000 14.37372  ?  322 ILE A HA   1 
ATOM   3731 H HB   . ILE A 1 241 ? 22.70089  -13.21905 -32.11656 1.000 16.90252  ?  322 ILE A HB   1 
ATOM   3732 H HG12 . ILE A 1 241 ? 24.12809  -14.74816 -33.58439 1.000 22.14057  ?  322 ILE A HG12 1 
ATOM   3733 H HG13 . ILE A 1 241 ? 25.55091  -14.07370 -32.74201 1.000 22.14057  ?  322 ILE A HG13 1 
ATOM   3734 H HG21 . ILE A 1 241 ? 23.21046  -12.79041 -34.46005 1.000 20.60446  ?  322 ILE A HG21 1 
ATOM   3735 H HG22 . ILE A 1 241 ? 23.16210  -11.28023 -33.50951 1.000 20.60446  ?  322 ILE A HG22 1 
ATOM   3736 H HG23 . ILE A 1 241 ? 24.73146  -11.98752 -33.98211 1.000 20.60446  ?  322 ILE A HG23 1 
ATOM   3737 H HD11 . ILE A 1 241 ? 23.62699  -16.06962 -31.91609 1.000 30.27043  ?  322 ILE A HD11 1 
ATOM   3738 H HD12 . ILE A 1 241 ? 25.29753  -15.75416 -31.37178 1.000 30.27043  ?  322 ILE A HD12 1 
ATOM   3739 H HD13 . ILE A 1 241 ? 23.94398  -14.80934 -30.69228 1.000 30.27043  ?  322 ILE A HD13 1 
ATOM   3740 N N    . HIS A 1 242 ? 25.89757  -10.52861 -32.11782 1.000 12.01323  ?  323 HIS A N    1 
ATOM   3741 C CA   . HIS A 1 242 ? 27.22543  -9.98975  -32.35689 1.000 11.67882  ?  323 HIS A CA   1 
ATOM   3742 C C    . HIS A 1 242 ? 27.95501  -9.73791  -31.05865 1.000 12.20658  ?  323 HIS A C    1 
ATOM   3743 O O    . HIS A 1 242 ? 29.14423  -10.02159 -30.93507 1.000 14.23548  ?  323 HIS A O    1 
ATOM   3744 C CB   . HIS A 1 242 ? 27.15400  -8.67726  -33.14825 1.000 15.10533  ?  323 HIS A CB   1 
ATOM   3745 C CG   . HIS A 1 242 ? 26.98828  -8.86161  -34.61260 1.000 14.38733  ?  323 HIS A CG   1 
ATOM   3746 N ND1  . HIS A 1 242 ? 25.77395  -9.15598  -35.17623 1.000 16.27840  ?  323 HIS A ND1  1 
ATOM   3747 C CD2  . HIS A 1 242 ? 27.87935  -8.78407  -35.62472 1.000 20.61364  ?  323 HIS A CD2  1 
ATOM   3748 C CE1  . HIS A 1 242 ? 25.91190  -9.27644  -36.48539 1.000 21.61286  ?  323 HIS A CE1  1 
ATOM   3749 N NE2  . HIS A 1 242 ? 27.18595  -9.06274  -36.77739 1.000 20.54216  ?  323 HIS A NE2  1 
ATOM   3750 H H    A HIS A 1 242 ? 25.12422  -9.92408  -32.39508 1.000 14.41587  ?  323 HIS A H    1 
ATOM   3751 D D    B HIS A 1 242 ? 25.12593  -9.92227  -32.39590 0.000 14.41587  ?  323 HIS A D    1 
ATOM   3752 H HA   . HIS A 1 242 ? 27.77506  -10.72176 -32.94863 1.000 14.01459  ?  323 HIS A HA   1 
ATOM   3753 H HB2  . HIS A 1 242 ? 26.30303  -8.09867  -32.78882 1.000 18.12639  ?  323 HIS A HB2  1 
ATOM   3754 H HB3  . HIS A 1 242 ? 28.07763  -8.12144  -32.98678 1.000 18.12639  ?  323 HIS A HB3  1 
ATOM   3755 H HD2  . HIS A 1 242 ? 28.93038  -8.54917  -35.54371 1.000 24.73637  ?  323 HIS A HD2  1 
ATOM   3756 H HE1  . HIS A 1 242 ? 25.12685  -9.50756  -37.19015 1.000 25.93543  ?  323 HIS A HE1  1 
ATOM   3757 N N    . TYR A 1 243 ? 27.25417  -9.18275  -30.05732 1.000 12.38938  ?  324 TYR A N    1 
ATOM   3758 C CA   . TYR A 1 243 ? 27.87458  -8.92679  -28.76003 1.000 11.64184  ?  324 TYR A CA   1 
ATOM   3759 C C    . TYR A 1 243 ? 28.32531  -10.23109 -28.12000 1.000 11.90665  ?  324 TYR A C    1 
ATOM   3760 O O    . TYR A 1 243 ? 29.46633  -10.35196 -27.69343 1.000 12.28199  ?  324 TYR A O    1 
ATOM   3761 C CB   . TYR A 1 243 ? 26.82304  -8.18778  -27.89452 1.000 11.52567  ?  324 TYR A CB   1 
ATOM   3762 C CG   . TYR A 1 243 ? 27.12092  -8.07005  -26.42043 1.000 10.26238  ?  324 TYR A CG   1 
ATOM   3763 C CD1  . TYR A 1 243 ? 28.38356  -7.82165  -25.95802 1.000 10.09082  ?  324 TYR A CD1  1 
ATOM   3764 C CD2  . TYR A 1 243 ? 26.11173  -8.15405  -25.50925 1.000 12.23925  ?  324 TYR A CD2  1 
ATOM   3765 C CE1  . TYR A 1 243 ? 28.65766  -7.70161  -24.62871 1.000 11.13419  ?  324 TYR A CE1  1 
ATOM   3766 C CE2  . TYR A 1 243 ? 26.37850  -8.01290  -24.13687 1.000 11.51760  ?  324 TYR A CE2  1 
ATOM   3767 C CZ   . TYR A 1 243 ? 27.63460  -7.79352  -23.70659 1.000 11.58442  ?  324 TYR A CZ   1 
ATOM   3768 O OH   . TYR A 1 243 ? 27.93117  -7.70050  -22.39345 1.000 12.60361  ?  324 TYR A OH   1 
ATOM   3769 H H    A TYR A 1 243 ? 26.27420  -8.90615  -30.11700 0.999 14.86726  ?  324 TYR A H    1 
ATOM   3770 D D    B TYR A 1 243 ? 26.27428  -8.90539  -30.11473 0.001 14.86726  ?  324 TYR A D    1 
ATOM   3771 H HA   . TYR A 1 243 ? 28.76278  -8.30184  -28.85306 1.000 13.97021  ?  324 TYR A HA   1 
ATOM   3772 H HB2  . TYR A 1 243 ? 26.72033  -7.17369  -28.28076 1.000 13.83080  ?  324 TYR A HB2  1 
ATOM   3773 H HB3  . TYR A 1 243 ? 25.87600  -8.71950  -27.98668 1.000 13.83080  ?  324 TYR A HB3  1 
ATOM   3774 H HD1  . TYR A 1 243 ? 29.18950  -7.71726  -26.66932 1.000 12.10898  ?  324 TYR A HD1  1 
ATOM   3775 H HD2  . TYR A 1 243 ? 25.10009  -8.33026  -25.84382 1.000 14.68710  ?  324 TYR A HD2  1 
ATOM   3776 H HE1  . TYR A 1 243 ? 29.67208  -7.53508  -24.29761 1.000 13.36103  ?  324 TYR A HE1  1 
ATOM   3777 H HE2  . TYR A 1 243 ? 25.57075  -8.08088  -23.42320 1.000 13.82112  ?  324 TYR A HE2  1 
ATOM   3778 N N    . ILE A 1 244 ? 27.44625  -11.23162 -28.09075 1.000 11.16259  ?  325 ILE A N    1 
ATOM   3779 C CA   . ILE A 1 244 ? 27.81122  -12.51199 -27.46846 1.000 12.66912  ?  325 ILE A CA   1 
ATOM   3780 C C    . ILE A 1 244 ? 28.94973  -13.19560 -28.22631 1.000 12.91264  ?  325 ILE A C    1 
ATOM   3781 O O    . ILE A 1 244 ? 29.88706  -13.71283 -27.61849 1.000 13.38826  ?  325 ILE A O    1 
ATOM   3782 C CB   . ILE A 1 244 ? 26.56290  -13.40041 -27.36566 1.000 12.56778  ?  325 ILE A CB   1 
ATOM   3783 C CG1  . ILE A 1 244 ? 25.59938  -12.77552 -26.35653 1.000 12.40665  ?  325 ILE A CG1  1 
ATOM   3784 C CG2  . ILE A 1 244 ? 26.97121  -14.81932 -26.96747 1.000 16.65697  ?  325 ILE A CG2  1 
ATOM   3785 C CD1  . ILE A 1 244 ? 24.26123  -13.39075 -26.31901 1.000 17.49128  ?  325 ILE A CD1  1 
ATOM   3786 H H    A ILE A 1 244 ? 26.50224  -11.19433 -28.47526 0.905 13.39511  ?  325 ILE A H    1 
ATOM   3787 D D    B ILE A 1 244 ? 26.50191  -11.19633 -28.47465 0.095 13.39511  ?  325 ILE A D    1 
ATOM   3788 H HA   . ILE A 1 244 ? 28.18572  -12.32116 -26.46276 1.000 15.20294  ?  325 ILE A HA   1 
ATOM   3789 H HB   . ILE A 1 244 ? 26.05741  -13.46462 -28.32922 1.000 15.08134  ?  325 ILE A HB   1 
ATOM   3790 H HG12 . ILE A 1 244 ? 26.03190  -12.87022 -25.36051 1.000 14.88798  ?  325 ILE A HG12 1 
ATOM   3791 H HG13 . ILE A 1 244 ? 25.46944  -11.72291 -26.60800 1.000 14.88798  ?  325 ILE A HG13 1 
ATOM   3792 H HG21 . ILE A 1 244 ? 26.10931  -15.47863 -27.07016 1.000 19.98836  ?  325 ILE A HG21 1 
ATOM   3793 H HG22 . ILE A 1 244 ? 27.77548  -15.15418 -27.62254 1.000 19.98836  ?  325 ILE A HG22 1 
ATOM   3794 H HG23 . ILE A 1 244 ? 27.31309  -14.81295 -25.93249 1.000 19.98836  ?  325 ILE A HG23 1 
ATOM   3795 H HD11 . ILE A 1 244 ? 23.84992  -13.40748 -27.32828 1.000 20.98954  ?  325 ILE A HD11 1 
ATOM   3796 H HD12 . ILE A 1 244 ? 24.34877  -14.40762 -25.93639 1.000 20.98954  ?  325 ILE A HD12 1 
ATOM   3797 H HD13 . ILE A 1 244 ? 23.61804  -12.80170 -25.66523 1.000 20.98954  ?  325 ILE A HD13 1 
ATOM   3798 N N    . ASN A 1 245 ? 28.90419  -13.18586 -29.57729 1.000 12.42012  ?  326 ASN A N    1 
ATOM   3799 C CA   . ASN A 1 245 ? 29.97961  -13.80196 -30.35263 1.000 13.32325  ?  326 ASN A CA   1 
ATOM   3800 C C    . ASN A 1 245 ? 31.31475  -13.11619 -30.08797 1.000 13.78360  ?  326 ASN A C    1 
ATOM   3801 O O    . ASN A 1 245 ? 32.38311  -13.74667 -30.20437 1.000 16.65178  ?  326 ASN A O    1 
ATOM   3802 C CB   . ASN A 1 245 ? 29.67262  -13.75156 -31.83570 1.000 15.90065  ?  326 ASN A CB   1 
ATOM   3803 C CG   . ASN A 1 245 ? 28.65814  -14.77712 -32.27789 1.000 19.18480  ?  326 ASN A CG   1 
ATOM   3804 O OD1  . ASN A 1 245 ? 28.35994  -15.72253 -31.55704 1.000 22.80632  ?  326 ASN A OD1  1 
ATOM   3805 N ND2  . ASN A 1 245 ? 28.12551  -14.60232 -33.49586 1.000 23.20217  ?  326 ASN A ND2  1 
ATOM   3806 H H    A ASN A 1 245 ? 28.15788  -12.77127 -30.13546 0.957 14.90414  ?  326 ASN A H    1 
ATOM   3807 D D    B ASN A 1 245 ? 28.15915  -12.77201 -30.13769 0.043 14.90414  ?  326 ASN A D    1 
ATOM   3808 H HA   . ASN A 1 245 ? 30.05199  -14.84919 -30.05910 1.000 15.98790  ?  326 ASN A HA   1 
ATOM   3809 H HB2  . ASN A 1 245 ? 29.27729  -12.76548 -32.07954 1.000 19.08078  ?  326 ASN A HB2  1 
ATOM   3810 H HB3  . ASN A 1 245 ? 30.59272  -13.93220 -32.39148 1.000 19.08078  ?  326 ASN A HB3  1 
ATOM   3811 N N    . ALA A 1 246 ? 31.30346  -11.81882 -29.75148 1.000 13.10804  ?  327 ALA A N    1 
ATOM   3812 C CA   . ALA A 1 246 ? 32.53517  -11.10783 -29.51798 1.000 13.31615  ?  327 ALA A CA   1 
ATOM   3813 C C    . ALA A 1 246 ? 33.03346  -11.27645 -28.09973 1.000 14.39834  ?  327 ALA A C    1 
ATOM   3814 O O    . ALA A 1 246 ? 34.25337  -11.28056 -27.86260 1.000 17.11157  ?  327 ALA A O    1 
ATOM   3815 C CB   . ALA A 1 246 ? 32.30255  -9.62903  -29.79210 1.000 14.87526  ?  327 ALA A CB   1 
ATOM   3816 H H    A ALA A 1 246 ? 30.46153  -11.25425 -29.63824 1.000 15.72964  ?  327 ALA A H    1 
ATOM   3817 D D    B ALA A 1 246 ? 30.46261  -11.25273 -29.63780 0.000 15.72964  ?  327 ALA A D    1 
ATOM   3818 H HA   . ALA A 1 246 ? 33.30287  -11.48975 -30.19094 1.000 15.97938  ?  327 ALA A HA   1 
ATOM   3819 H HB1  . ALA A 1 246 ? 33.26489  -9.14111  -29.94677 1.000 17.85031  ?  327 ALA A HB1  1 
ATOM   3820 H HB2  . ALA A 1 246 ? 31.68595  -9.52634  -30.68505 1.000 17.85031  ?  327 ALA A HB2  1 
ATOM   3821 H HB3  . ALA A 1 246 ? 31.79406  -9.18516  -28.93622 1.000 17.85031  ?  327 ALA A HB3  1 
ATOM   3822 N N    . LEU A 1 247 ? 32.13268  -11.43169 -27.10300 1.000 12.81776  ?  328 LEU A N    1 
ATOM   3823 C CA   . LEU A 1 247 ? 32.53801  -11.51573 -25.71188 1.000 11.22201  ?  328 LEU A CA   1 
ATOM   3824 C C    . LEU A 1 247 ? 32.84714  -12.94755 -25.27967 1.000 13.58226  ?  328 LEU A C    1 
ATOM   3825 O O    . LEU A 1 247 ? 33.77888  -13.16109 -24.51285 1.000 14.16867  ?  328 LEU A O    1 
ATOM   3826 C CB   . LEU A 1 247 ? 31.39661  -10.97355 -24.82677 1.000 12.62350  ?  328 LEU A CB   1 
ATOM   3827 C CG   . LEU A 1 247 ? 31.63472  -10.94367 -23.31264 1.000 13.41729  ?  328 LEU A CG   1 
ATOM   3828 C CD1  . LEU A 1 247 ? 32.85752  -10.11409 -22.99556 1.000 17.13806  ?  328 LEU A CD1  1 
ATOM   3829 C CD2  . LEU A 1 247 ? 30.48215  -10.41462 -22.55126 1.000 14.65433  ?  328 LEU A CD2  1 
ATOM   3830 H H    A LEU A 1 247 ? 31.12496  -11.50020 -27.24518 0.935 15.38131  ?  328 LEU A H    1 
ATOM   3831 D D    B LEU A 1 247 ? 31.12495  -11.50021 -27.24507 0.065 15.38131  ?  328 LEU A D    1 
ATOM   3832 H HA   . LEU A 1 247 ? 33.43519  -10.91373 -25.56771 1.000 13.46642  ?  328 LEU A HA   1 
ATOM   3833 H HB2  . LEU A 1 247 ? 31.19284  -9.94819  -25.13534 1.000 15.14820  ?  328 LEU A HB2  1 
ATOM   3834 H HB3  . LEU A 1 247 ? 30.51782  -11.59562 -24.99668 1.000 15.14820  ?  328 LEU A HB3  1 
ATOM   3835 H HG   . LEU A 1 247 ? 31.78249  -11.97575 -22.99473 1.000 16.10075  ?  328 LEU A HG   1 
ATOM   3836 H HD11 . LEU A 1 247 ? 33.71724  -10.53579 -23.51629 1.000 20.56567  ?  328 LEU A HD11 1 
ATOM   3837 H HD12 . LEU A 1 247 ? 32.68743  -9.08995  -23.32771 1.000 20.56567  ?  328 LEU A HD12 1 
ATOM   3838 H HD13 . LEU A 1 247 ? 33.02927  -10.13213 -21.91933 1.000 20.56567  ?  328 LEU A HD13 1 
ATOM   3839 H HD21 . LEU A 1 247 ? 30.73679  -10.39260 -21.49165 1.000 17.58520  ?  328 LEU A HD21 1 
ATOM   3840 H HD22 . LEU A 1 247 ? 30.25846  -9.40671  -22.90081 1.000 17.58520  ?  328 LEU A HD22 1 
ATOM   3841 H HD23 . LEU A 1 247 ? 29.62167  -11.06377 -22.71335 1.000 17.58520  ?  328 LEU A HD23 1 
ATOM   3842 N N    . ALA A 1 248 ? 32.08453  -13.92173 -25.76803 1.000 13.84147  ?  329 ALA A N    1 
ATOM   3843 C CA   . ALA A 1 248 ? 32.26879  -15.30881 -25.33095 1.000 15.55457  ?  329 ALA A CA   1 
ATOM   3844 C C    . ALA A 1 248 ? 33.70011  -15.81095 -25.49027 1.000 15.41321  ?  329 ALA A C    1 
ATOM   3845 O O    . ALA A 1 248 ? 34.23738  -16.36237 -24.51689 1.000 15.48583  ?  329 ALA A O    1 
ATOM   3846 C CB   . ALA A 1 248 ? 31.25152  -16.23461 -25.99785 1.000 17.37848  ?  329 ALA A CB   1 
ATOM   3847 H H    A ALA A 1 248 ? 31.34257  -13.79004 -26.45546 0.776 16.60977  ?  329 ALA A H    1 
ATOM   3848 D D    B ALA A 1 248 ? 31.34231  -13.79137 -26.45543 0.224 16.60977  ?  329 ALA A D    1 
ATOM   3849 H HA   . ALA A 1 248 ? 32.04231  -15.33155 -24.26498 1.000 18.66549  ?  329 ALA A HA   1 
ATOM   3850 H HB1  . ALA A 1 248 ? 31.49523  -17.26750 -25.74914 1.000 20.85417  ?  329 ALA A HB1  1 
ATOM   3851 H HB2  . ALA A 1 248 ? 30.25473  -15.98930 -25.63135 1.000 20.85417  ?  329 ALA A HB2  1 
ATOM   3852 H HB3  . ALA A 1 248 ? 31.29614  -16.09182 -27.07754 1.000 20.85417  ?  329 ALA A HB3  1 
ATOM   3853 N N    . PRO A 1 249 ? 34.39911  -15.58286 -26.61618 1.000 16.03755  ?  330 PRO A N    1 
ATOM   3854 C CA   . PRO A 1 249 ? 35.80252  -16.02912 -26.70006 1.000 17.71573  ?  330 PRO A CA   1 
ATOM   3855 C C    . PRO A 1 249 ? 36.70764  -15.41041 -25.65986 1.000 20.08806  ?  330 PRO A C    1 
ATOM   3856 O O    . PRO A 1 249 ? 37.67888  -16.05721 -25.22697 1.000 20.08545  ?  330 PRO A O    1 
ATOM   3857 C CB   . PRO A 1 249 ? 36.22382  -15.59774 -28.11177 1.000 23.70695  ?  330 PRO A CB   1 
ATOM   3858 C CG   . PRO A 1 249 ? 34.95354  -15.51980 -28.88500 1.000 22.24831  ?  330 PRO A CG   1 
ATOM   3859 C CD   . PRO A 1 249 ? 33.88804  -15.07953 -27.90879 1.000 18.34417  ?  330 PRO A CD   1 
ATOM   3860 H HA   . PRO A 1 249 ? 35.83855  -17.11503 -26.61278 1.000 21.25887  ?  330 PRO A HA   1 
ATOM   3861 H HB2  . PRO A 1 249 ? 36.71641  -14.62622 -28.07151 1.000 28.44834  ?  330 PRO A HB2  1 
ATOM   3862 H HB3  . PRO A 1 249 ? 36.89715  -16.33961 -28.54114 1.000 28.44834  ?  330 PRO A HB3  1 
ATOM   3863 H HG2  . PRO A 1 249 ? 35.06013  -14.79329 -29.69057 1.000 26.69798  ?  330 PRO A HG2  1 
ATOM   3864 H HG3  . PRO A 1 249 ? 34.71559  -16.50063 -29.29663 1.000 26.69798  ?  330 PRO A HG3  1 
ATOM   3865 H HD2  . PRO A 1 249 ? 33.79610  -13.99349 -27.89551 1.000 22.01301  ?  330 PRO A HD2  1 
ATOM   3866 H HD3  . PRO A 1 249 ? 32.92643  -15.53214 -28.15080 1.000 22.01301  ?  330 PRO A HD3  1 
ATOM   3867 N N    . LEU A 1 250 ? 36.42571  -14.18235 -25.20719 1.000 16.30444  ?  331 LEU A N    1 
ATOM   3868 C CA   . LEU A 1 250 ? 37.28991  -13.55110 -24.23199 1.000 17.21795  ?  331 LEU A CA   1 
ATOM   3869 C C    . LEU A 1 250 ? 37.13739  -14.20861 -22.87815 1.000 18.63816  ?  331 LEU A C    1 
ATOM   3870 O O    . LEU A 1 250 ? 38.11220  -14.36264 -22.13367 1.000 21.04266  ?  331 LEU A O    1 
ATOM   3871 C CB   . LEU A 1 250 ? 37.02251  -12.04828 -24.15506 1.000 18.71980  ?  331 LEU A CB   1 
ATOM   3872 C CG   . LEU A 1 250 ? 37.14342  -11.28190 -25.47135 1.000 21.71655  ?  331 LEU A CG   1 
ATOM   3873 C CD1  . LEU A 1 250 ? 36.72387  -9.83271  -25.28371 1.000 26.86763  ?  331 LEU A CD1  1 
ATOM   3874 C CD2  . LEU A 1 250 ? 38.57002  -11.31934 -26.00618 1.000 30.74034  ?  331 LEU A CD2  1 
ATOM   3875 H H    A LEU A 1 250 ? 35.62415  -13.62122 -25.49536 0.645 19.56533  ?  331 LEU A H    1 
ATOM   3876 D D    B LEU A 1 250 ? 35.62493  -13.61928 -25.49374 0.355 19.56533  ?  331 LEU A D    1 
ATOM   3877 H HA   . LEU A 1 250 ? 38.32540  -13.66681 -24.55208 1.000 20.66153  ?  331 LEU A HA   1 
ATOM   3878 H HB2  . LEU A 1 250 ? 36.00692  -11.90154 -23.78746 1.000 22.46376  ?  331 LEU A HB2  1 
ATOM   3879 H HB3  . LEU A 1 250 ? 37.73787  -11.61038 -23.45893 1.000 22.46376  ?  331 LEU A HB3  1 
ATOM   3880 H HG   . LEU A 1 250 ? 36.48688  -11.75940 -26.19870 1.000 26.05986  ?  331 LEU A HG   1 
ATOM   3881 H HD11 . LEU A 1 250 ? 37.59127  -9.18988  -25.43369 1.000 32.24115  ?  331 LEU A HD11 1 
ATOM   3882 H HD12 . LEU A 1 250 ? 35.95076  -9.58986  -26.01270 1.000 32.24115  ?  331 LEU A HD12 1 
ATOM   3883 H HD13 . LEU A 1 250 ? 36.33579  -9.70359  -24.27335 1.000 32.24115  ?  331 LEU A HD13 1 
ATOM   3884 H HD21 . LEU A 1 250 ? 38.95460  -12.33563 -25.92042 1.000 36.88840  ?  331 LEU A HD21 1 
ATOM   3885 H HD22 . LEU A 1 250 ? 38.56531  -11.01069 -27.05156 1.000 36.88840  ?  331 LEU A HD22 1 
ATOM   3886 H HD23 . LEU A 1 250 ? 39.18670  -10.63787 -25.42018 1.000 36.88840  ?  331 LEU A HD23 1 
ATOM   3887 N N    . LEU A 1 251 ? 35.93069  -14.67519 -22.55651 1.000 15.54953  ?  332 LEU A N    1 
ATOM   3888 C CA   . LEU A 1 251 ? 35.74836  -15.41252 -21.30600 1.000 16.80550  ?  332 LEU A CA   1 
ATOM   3889 C C    . LEU A 1 251 ? 36.38608  -16.79091 -21.39253 1.000 14.10260  ?  332 LEU A C    1 
ATOM   3890 O O    . LEU A 1 251 ? 37.03648  -17.24025 -20.43859 1.000 16.42440  ?  332 LEU A O    1 
ATOM   3891 C CB   . LEU A 1 251 ? 34.24925  -15.53516 -20.99878 1.000 14.21817  ?  332 LEU A CB   1 
ATOM   3892 C CG   . LEU A 1 251 ? 33.51921  -14.19998 -20.93743 1.000 15.11792  ?  332 LEU A CG   1 
ATOM   3893 C CD1  . LEU A 1 251 ? 32.01283  -14.44591 -20.87097 1.000 19.19561  ?  332 LEU A CD1  1 
ATOM   3894 C CD2  . LEU A 1 251 ? 33.98036  -13.34755 -19.79957 1.000 17.61630  ?  332 LEU A CD2  1 
ATOM   3895 H H    A LEU A 1 251 ? 35.08744  -14.56416 -23.11954 0.914 18.65944  ?  332 LEU A H    1 
ATOM   3896 D D    B LEU A 1 251 ? 35.08607  -14.56548 -23.11774 0.086 18.65944  ?  332 LEU A D    1 
ATOM   3897 H HA   . LEU A 1 251 ? 36.22412  -14.86689 -20.49111 1.000 20.16660  ?  332 LEU A HA   1 
ATOM   3898 H HB2  . LEU A 1 251 ? 33.78111  -16.13453 -21.77961 1.000 17.06180  ?  332 LEU A HB2  1 
ATOM   3899 H HB3  . LEU A 1 251 ? 34.13024  -16.02395 -20.03182 1.000 17.06180  ?  332 LEU A HB3  1 
ATOM   3900 H HG   . LEU A 1 251 ? 33.74792  -13.63621 -21.84184 1.000 18.14150  ?  332 LEU A HG   1 
ATOM   3901 H HD11 . LEU A 1 251 ? 31.53946  -13.61123 -20.35393 1.000 23.03473  ?  332 LEU A HD11 1 
ATOM   3902 H HD12 . LEU A 1 251 ? 31.62114  -14.52527 -21.88506 1.000 23.03473  ?  332 LEU A HD12 1 
ATOM   3903 H HD13 . LEU A 1 251 ? 31.82819  -15.37261 -20.32761 1.000 23.03473  ?  332 LEU A HD13 1 
ATOM   3904 H HD21 . LEU A 1 251 ? 34.20296  -13.98648 -18.94498 1.000 21.13956  ?  332 LEU A HD21 1 
ATOM   3905 H HD22 . LEU A 1 251 ? 34.87663  -12.80610 -20.10230 1.000 21.13956  ?  332 LEU A HD22 1 
ATOM   3906 H HD23 . LEU A 1 251 ? 33.18998  -12.64292 -19.54097 1.000 21.13956  ?  332 LEU A HD23 1 
ATOM   3907 N N    . GLN A 1 252 ? 36.20924  -17.46883 -22.52992 1.000 15.73912  ?  333 GLN A N    1 
ATOM   3908 C CA   . GLN A 1 252 ? 36.84133  -18.78391 -22.71169 1.000 20.36168  ?  333 GLN A CA   1 
ATOM   3909 C C    . GLN A 1 252 ? 38.34999  -18.70872 -22.56657 1.000 20.38419  ?  333 GLN A C    1 
ATOM   3910 O O    . GLN A 1 252 ? 38.95766  -19.61120 -21.99048 1.000 22.00878  ?  333 GLN A O    1 
ATOM   3911 C CB   . GLN A 1 252 ? 36.50787  -19.35252 -24.09323 1.000 17.63459  ?  333 GLN A CB   1 
ATOM   3912 C CG   . GLN A 1 252 ? 35.09403  -19.78755 -24.20747 1.000 24.81955  ?  333 GLN A CG   1 
ATOM   3913 C CD   . GLN A 1 252 ? 34.69141  -20.23082 -25.62046 1.000 37.70713  ?  333 GLN A CD   1 
ATOM   3914 O OE1  . GLN A 1 252 ? 35.28445  -19.82364 -26.62790 1.000 34.48270  ?  333 GLN A OE1  1 
ATOM   3915 N NE2  . GLN A 1 252 ? 33.66104  -21.06187 -25.68381 1.000 36.36087  ?  333 GLN A NE2  1 
ATOM   3916 H H    A GLN A 1 252 ? 35.65243  -17.14876 -23.32233 0.656 18.88695  ?  333 GLN A H    1 
ATOM   3917 D D    B GLN A 1 252 ? 35.65303  -17.15100 -23.32365 0.344 18.88695  ?  333 GLN A D    1 
ATOM   3918 H HA   . GLN A 1 252 ? 36.44266  -19.44777 -21.94458 1.000 24.43401  ?  333 GLN A HA   1 
ATOM   3919 H HB2  . GLN A 1 252 ? 36.68685  -18.58457 -24.84577 1.000 21.16151  ?  333 GLN A HB2  1 
ATOM   3920 H HB3  . GLN A 1 252 ? 37.14375  -20.21698 -24.28418 1.000 21.16151  ?  333 GLN A HB3  1 
ATOM   3921 H HG2  . GLN A 1 252 ? 34.93202  -20.63126 -23.53665 1.000 29.78346  ?  333 GLN A HG2  1 
ATOM   3922 H HG3  . GLN A 1 252 ? 34.44804  -18.95658 -23.92411 1.000 29.78346  ?  333 GLN A HG3  1 
ATOM   3923 N N    . GLN A 1 253 ? 38.96085  -17.64196 -23.07621 1.000 20.62195  ?  334 GLN A N    1 
ATOM   3924 C CA   A GLN A 1 253 ? 40.40867  -17.52114 -22.96594 0.606 27.09674  ?  334 GLN A CA   1 
ATOM   3925 C CA   B GLN A 1 253 ? 40.41005  -17.46093 -22.96625 0.394 27.29220  ?  334 GLN A CA   1 
ATOM   3926 C C    . GLN A 1 253 ? 40.86179  -17.49587 -21.50793 1.000 28.21546  ?  334 GLN A C    1 
ATOM   3927 O O    . GLN A 1 253 ? 41.96847  -17.96195 -21.18916 1.000 30.35084  ?  334 GLN A O    1 
ATOM   3928 C CB   A GLN A 1 253 ? 40.89779  -16.28402 -23.71887 0.606 32.74653  ?  334 GLN A CB   1 
ATOM   3929 C CB   B GLN A 1 253 ? 40.81990  -16.13594 -23.63182 0.394 33.07868  ?  334 GLN A CB   1 
ATOM   3930 C CG   A GLN A 1 253 ? 41.32440  -16.55739 -25.15328 0.606 37.41902  ?  334 GLN A CG   1 
ATOM   3931 C CG   B GLN A 1 253 ? 41.59473  -15.13231 -22.74607 0.394 43.58260  ?  334 GLN A CG   1 
ATOM   3932 C CD   A GLN A 1 253 ? 41.78802  -15.29138 -25.86943 0.606 53.06495  ?  334 GLN A CD   1 
ATOM   3933 C CD   B GLN A 1 253 ? 41.39145  -13.66679 -23.17248 0.394 41.17426  ?  334 GLN A CD   1 
ATOM   3934 O OE1  A GLN A 1 253 ? 41.15341  -14.84250 -26.82821 0.606 46.57272  ?  334 GLN A OE1  1 
ATOM   3935 O OE1  B GLN A 1 253 ? 40.84211  -12.85590 -22.41537 0.394 29.67560  ?  334 GLN A OE1  1 
ATOM   3936 N NE2  A GLN A 1 253 ? 42.88929  -14.71131 -25.40239 0.606 43.54961  ?  334 GLN A NE2  1 
ATOM   3937 N NE2  B GLN A 1 253 ? 41.82949  -13.33007 -24.38844 0.394 34.51534  ?  334 GLN A NE2  1 
ATOM   3938 H H    A GLN A 1 253 ? 38.49698  -16.87015 -23.55531 0.656 24.74634  ?  334 GLN A H    1 
ATOM   3939 D D    B GLN A 1 253 ? 38.48884  -16.88463 -23.57024 0.344 24.74634  ?  334 GLN A D    1 
ATOM   3940 H HA   A GLN A 1 253 ? 40.87140  -18.38852 -23.43671 0.606 32.51609  ?  334 GLN A HA   1 
ATOM   3941 H HA   B GLN A 1 253 ? 40.91200  -18.27399 -23.49073 0.394 32.75065  ?  334 GLN A HA   1 
ATOM   3942 H HB2  A GLN A 1 253 ? 40.09114  -15.55149 -23.74733 0.606 39.29584  ?  334 GLN A HB2  1 
ATOM   3943 H HB2  B GLN A 1 253 ? 41.45730  -16.36829 -24.48495 0.394 39.69442  ?  334 GLN A HB2  1 
ATOM   3944 H HB3  A GLN A 1 253 ? 41.75748  -15.87156 -23.19074 0.606 39.29584  ?  334 GLN A HB3  1 
ATOM   3945 H HB3  B GLN A 1 253 ? 39.91425  -15.63201 -23.96940 0.394 39.69442  ?  334 GLN A HB3  1 
ATOM   3946 H HG2  A GLN A 1 253 ? 42.15075  -17.26819 -25.15113 0.606 44.90283  ?  334 GLN A HG2  1 
ATOM   3947 H HG2  B GLN A 1 253 ? 41.25253  -15.23230 -21.71602 0.394 52.29912  ?  334 GLN A HG2  1 
ATOM   3948 H HG3  A GLN A 1 253 ? 40.47956  -16.96955 -25.70508 0.606 44.90283  ?  334 GLN A HG3  1 
ATOM   3949 H HG3  B GLN A 1 253 ? 42.65995  -15.35489 -22.80829 0.394 52.29912  ?  334 GLN A HG3  1 
ATOM   3950 N N    . ALA A 1 254 ? 40.04063  -16.97713 -20.60830 1.000 24.37707  ?  335 ALA A N    1 
ATOM   3951 C CA   . ALA A 1 254 ? 40.39617  -16.91433 -19.20443 1.000 18.16487  ?  335 ALA A CA   1 
ATOM   3952 C C    . ALA A 1 254 ? 40.05316  -18.18160 -18.44910 1.000 24.29073  ?  335 ALA A C    1 
ATOM   3953 O O    . ALA A 1 254 ? 40.23776  -18.23691 -17.22272 1.000 35.13851  ?  335 ALA A O    1 
ATOM   3954 C CB   . ALA A 1 254 ? 39.67835  -15.74262 -18.53910 1.000 34.63998  ?  335 ALA A CB   1 
ATOM   3955 H H    A ALA A 1 254 ? 39.12099  -16.59218 -20.82389 0.618 29.25249  ?  335 ALA A H    1 
ATOM   3956 D D    B ALA A 1 254 ? 39.12116  -16.59245 -20.82510 0.382 29.25249  ?  335 ALA A D    1 
ATOM   3957 H HA   . ALA A 1 254 ? 41.47184  -16.75385 -19.13185 1.000 21.79784  ?  335 ALA A HA   1 
ATOM   3958 H HB1  . ALA A 1 254 ? 40.31293  -14.85831 -18.59750 1.000 41.56798  ?  335 ALA A HB1  1 
ATOM   3959 H HB2  . ALA A 1 254 ? 38.73822  -15.56052 -19.05976 1.000 41.56798  ?  335 ALA A HB2  1 
ATOM   3960 H HB3  . ALA A 1 254 ? 39.48335  -15.99196 -17.49607 1.000 41.56798  ?  335 ALA A HB3  1 
ATOM   3961 N N    . GLY A 1 255 ? 39.55933  -19.20584 -19.12958 1.000 20.66918  ?  336 GLY A N    1 
ATOM   3962 C CA   . GLY A 1 255 ? 39.25100  -20.45538 -18.50294 1.000 23.91245  ?  336 GLY A CA   1 
ATOM   3963 C C    . GLY A 1 255 ? 37.79121  -20.67540 -18.16959 1.000 22.18499  ?  336 GLY A C    1 
ATOM   3964 O O    . GLY A 1 255 ? 37.45441  -21.71395 -17.59021 1.000 22.45402  ?  336 GLY A O    1 
ATOM   3965 H H    A GLY A 1 255 ? 39.36388  -19.18679 -20.13050 0.583 24.80302  ?  336 GLY A H    1 
ATOM   3966 D D    B GLY A 1 255 ? 39.36421  -19.18582 -20.13054 0.417 24.80302  ?  336 GLY A D    1 
ATOM   3967 H HA2  . GLY A 1 255 ? 39.56206  -21.26161 -19.16726 1.000 28.69494  ?  336 GLY A HA2  1 
ATOM   3968 H HA3  . GLY A 1 255 ? 39.81505  -20.52442 -17.57279 1.000 28.69494  ?  336 GLY A HA3  1 
ATOM   3969 N N    . TRP A 1 256 ? 36.90657  -19.74097 -18.52572 1.000 21.02547  ?  337 TRP A N    1 
ATOM   3970 C CA   . TRP A 1 256 ? 35.48555  -19.85705 -18.18591 1.000 17.96290  ?  337 TRP A CA   1 
ATOM   3971 C C    . TRP A 1 256 ? 34.72121  -20.17702 -19.44874 1.000 14.91920  ?  337 TRP A C    1 
ATOM   3972 O O    . TRP A 1 256 ? 34.59157  -19.33853 -20.33830 1.000 17.55595  ?  337 TRP A O    1 
ATOM   3973 C CB   . TRP A 1 256 ? 35.05437  -18.55054 -17.56937 1.000 15.60255  ?  337 TRP A CB   1 
ATOM   3974 C CG   . TRP A 1 256 ? 33.66873  -18.53091 -17.02296 1.000 14.03435  ?  337 TRP A CG   1 
ATOM   3975 C CD1  . TRP A 1 256 ? 32.84937  -19.60363 -16.76730 1.000 16.28221  ?  337 TRP A CD1  1 
ATOM   3976 C CD2  . TRP A 1 256 ? 32.93375  -17.36972 -16.68458 1.000 12.42212  ?  337 TRP A CD2  1 
ATOM   3977 N NE1  . TRP A 1 256 ? 31.63201  -19.14585 -16.30148 1.000 15.81518  ?  337 TRP A NE1  1 
ATOM   3978 C CE2  . TRP A 1 256 ? 31.66102  -17.78546 -16.22854 1.000 14.54441  ?  337 TRP A CE2  1 
ATOM   3979 C CE3  . TRP A 1 256 ? 33.23114  -16.00999 -16.73363 1.000 17.26563  ?  337 TRP A CE3  1 
ATOM   3980 C CZ2  . TRP A 1 256 ? 30.68449  -16.87810 -15.81541 1.000 16.49675  ?  337 TRP A CZ2  1 
ATOM   3981 C CZ3  . TRP A 1 256 ? 32.26326  -15.10399 -16.30979 1.000 21.06477  ?  337 TRP A CZ3  1 
ATOM   3982 C CH2  . TRP A 1 256 ? 31.01558  -15.55300 -15.87311 1.000 19.69605  ?  337 TRP A CH2  1 
ATOM   3983 H H    A TRP A 1 256 ? 37.14351  -18.89707 -19.04734 0.749 25.23056  ?  337 TRP A H    1 
ATOM   3984 D D    B TRP A 1 256 ? 37.14595  -18.89779 -19.04741 0.251 25.23056  ?  337 TRP A D    1 
ATOM   3985 H HA   . TRP A 1 256 ? 35.29567  -20.67397 -17.48972 1.000 21.55548  ?  337 TRP A HA   1 
ATOM   3986 H HB2  . TRP A 1 256 ? 35.73139  -18.31835 -16.74727 1.000 18.72306  ?  337 TRP A HB2  1 
ATOM   3987 H HB3  . TRP A 1 256 ? 35.11412  -17.77418 -18.33213 1.000 18.72306  ?  337 TRP A HB3  1 
ATOM   3988 H HD1  . TRP A 1 256 ? 33.11498  -20.64094 -16.90821 1.000 19.53865  ?  337 TRP A HD1  1 
ATOM   3989 H HE3  . TRP A 1 256 ? 34.19029  -15.66663 -17.09214 1.000 20.71875  ?  337 TRP A HE3  1 
ATOM   3990 H HZ2  . TRP A 1 256 ? 29.71608  -17.20620 -15.46767 1.000 19.79610  ?  337 TRP A HZ2  1 
ATOM   3991 H HZ3  . TRP A 1 256 ? 32.47904  -14.04581 -16.31881 1.000 25.27772  ?  337 TRP A HZ3  1 
ATOM   3992 H HH2  . TRP A 1 256 ? 30.28086  -14.82261 -15.56797 1.000 23.63526  ?  337 TRP A HH2  1 
ATOM   3993 N N    . ASP A 1 257 ? 34.22017  -21.40019 -19.51724 1.000 19.55530  ?  338 ASP A N    1 
ATOM   3994 C CA   . ASP A 1 257 ? 33.38452  -21.83770 -20.63158 1.000 21.96593  ?  338 ASP A CA   1 
ATOM   3995 C C    . ASP A 1 257 ? 31.98915  -21.30515 -20.34978 1.000 17.51046  ?  338 ASP A C    1 
ATOM   3996 O O    . ASP A 1 257 ? 31.10162  -22.03598 -19.91499 1.000 23.55048  ?  338 ASP A O    1 
ATOM   3997 C CB   . ASP A 1 257 ? 33.39583  -23.36268 -20.70420 1.000 27.31161  ?  338 ASP A CB   1 
ATOM   3998 C CG   . ASP A 1 257 ? 32.73218  -23.89530 -21.97191 1.000 36.65383  ?  338 ASP A CG   1 
ATOM   3999 O OD1  . ASP A 1 257 ? 32.75256  -23.19210 -23.00573 1.000 38.14325  ?  338 ASP A OD1  1 
ATOM   4000 O OD2  . ASP A 1 257 ? 32.17063  -25.00910 -21.91088 1.000 51.82986  -1 338 ASP A OD2  1 
ATOM   4001 H H    A ASP A 1 257 ? 34.37427  -22.12062 -18.81181 0.620 23.46636  ?  338 ASP A H    1 
ATOM   4002 D D    B ASP A 1 257 ? 34.37486  -22.11996 -18.81125 0.380 23.46636  ?  338 ASP A D    1 
ATOM   4003 H HA   . ASP A 1 257 ? 33.74494  -21.44117 -21.58077 1.000 26.35912  ?  338 ASP A HA   1 
ATOM   4004 H HB2  . ASP A 1 257 ? 34.42832  -23.71182 -20.69133 1.000 32.77394  ?  338 ASP A HB2  1 
ATOM   4005 H HB3  . ASP A 1 257 ? 32.85596  -23.76371 -19.84640 1.000 32.77394  ?  338 ASP A HB3  1 
ATOM   4006 N N    . ALA A 1 258 ? 31.80469  -20.01563 -20.58006 1.000 14.51754  ?  339 ALA A N    1 
ATOM   4007 C CA   . ALA A 1 258 ? 30.57102  -19.34170 -20.18147 1.000 12.42955  ?  339 ALA A CA   1 
ATOM   4008 C C    . ALA A 1 258 ? 29.53141  -19.45918 -21.28202 1.000 13.21287  ?  339 ALA A C    1 
ATOM   4009 O O    . ALA A 1 258 ? 29.85007  -19.41746 -22.47298 1.000 15.40878  ?  339 ALA A O    1 
ATOM   4010 C CB   . ALA A 1 258 ? 30.87480  -17.87185 -19.91556 1.000 14.45087  ?  339 ALA A CB   1 
ATOM   4011 H H    A ALA A 1 258 ? 32.48463  -19.40891 -21.03828 0.484 17.42105  ?  339 ALA A H    1 
ATOM   4012 D D    B ALA A 1 258 ? 32.48508  -19.40946 -21.03834 0.516 17.42105  ?  339 ALA A D    1 
ATOM   4013 H HA   . ALA A 1 258 ? 30.16093  -19.79807 -19.28056 1.000 14.91546  ?  339 ALA A HA   1 
ATOM   4014 H HB1  . ALA A 1 258 ? 31.43057  -17.46580 -20.76075 1.000 17.34105  ?  339 ALA A HB1  1 
ATOM   4015 H HB2  . ALA A 1 258 ? 29.93584  -17.33174 -19.79416 1.000 17.34105  ?  339 ALA A HB2  1 
ATOM   4016 H HB3  . ALA A 1 258 ? 31.47015  -17.79141 -19.00607 1.000 17.34105  ?  339 ALA A HB3  1 
ATOM   4017 N N    . THR A 1 259 ? 28.27065  -19.61103 -20.87395 1.000 11.12768  ?  340 THR A N    1 
ATOM   4018 C CA   . THR A 1 259 ? 27.15654  -19.55354 -21.78910 1.000 12.05620  ?  340 THR A CA   1 
ATOM   4019 C C    . THR A 1 259 ? 26.22354  -18.40901 -21.37888 1.000 11.44458  ?  340 THR A C    1 
ATOM   4020 O O    . THR A 1 259 ? 26.41682  -17.75162 -20.35686 1.000 13.28890  ?  340 THR A O    1 
ATOM   4021 C CB   . THR A 1 259 ? 26.40535  -20.88062 -21.84604 1.000 10.31391  ?  340 THR A CB   1 
ATOM   4022 O OG1  . THR A 1 259 ? 26.10241  -21.30293 -20.51256 1.000 13.70254  ?  340 THR A OG1  1 
ATOM   4023 C CG2  . THR A 1 259 ? 27.26716  -21.92198 -22.55956 1.000 17.55638  ?  340 THR A CG2  1 
ATOM   4024 H H    A THR A 1 259 ? 28.00088  -19.77610 -19.90422 0.979 13.35321  ?  340 THR A H    1 
ATOM   4025 D D    B THR A 1 259 ? 28.00321  -19.77603 -19.90356 0.021 13.35321  ?  340 THR A D    1 
ATOM   4026 H HA   . THR A 1 259 ? 27.52336  -19.35070 -22.79528 1.000 14.46744  ?  340 THR A HA   1 
ATOM   4027 H HB   . THR A 1 259 ? 25.47135  -20.77852 -22.39860 1.000 12.37669  ?  340 THR A HB   1 
ATOM   4028 H HG21 . THR A 1 259 ? 27.08834  -21.88097 -23.63401 1.000 21.06765  ?  340 THR A HG21 1 
ATOM   4029 H HG22 . THR A 1 259 ? 28.32240  -21.72653 -22.36886 1.000 21.06765  ?  340 THR A HG22 1 
ATOM   4030 H HG23 . THR A 1 259 ? 27.02133  -22.92041 -22.19789 1.000 21.06765  ?  340 THR A HG23 1 
ATOM   4031 N N    . PHE A 1 260 ? 25.20454  -18.16932 -22.18824 1.000 10.44284  ?  341 PHE A N    1 
ATOM   4032 C CA   . PHE A 1 260 ? 24.43173  -16.95015 -22.13601 1.000 10.22267  ?  341 PHE A CA   1 
ATOM   4033 C C    . PHE A 1 260 ? 22.96211  -17.26976 -22.22375 1.000 10.11573  ?  341 PHE A C    1 
ATOM   4034 O O    . PHE A 1 260 ? 22.54245  -18.23448 -22.85580 1.000 11.69364  ?  341 PHE A O    1 
ATOM   4035 C CB   . PHE A 1 260 ? 24.78127  -16.00825 -23.32490 1.000 10.45343  ?  341 PHE A CB   1 
ATOM   4036 C CG   . PHE A 1 260 ? 26.14317  -15.40869 -23.26972 1.000 11.05870  ?  341 PHE A CG   1 
ATOM   4037 C CD1  . PHE A 1 260 ? 27.25869  -16.17136 -23.53975 1.000 14.61371  ?  341 PHE A CD1  1 
ATOM   4038 C CD2  . PHE A 1 260 ? 26.31489  -14.08354 -22.93668 1.000 11.76418  ?  341 PHE A CD2  1 
ATOM   4039 C CE1  . PHE A 1 260 ? 28.54000  -15.62284 -23.45255 1.000 16.05510  ?  341 PHE A CE1  1 
ATOM   4040 C CE2  . PHE A 1 260 ? 27.58512  -13.53366 -22.88184 1.000 13.63420  ?  341 PHE A CE2  1 
ATOM   4041 C CZ   . PHE A 1 260 ? 28.68079  -14.29334 -23.14393 1.000 15.51297  ?  341 PHE A CZ   1 
ATOM   4042 H H    A PHE A 1 260 ? 24.88645  -18.81983 -22.90661 0.915 12.53141  ?  341 PHE A H    1 
ATOM   4043 D D    B PHE A 1 260 ? 24.88768  -18.82094 -22.90615 0.085 12.53141  ?  341 PHE A D    1 
ATOM   4044 H HA   . PHE A 1 260 ? 24.63711  -16.44665 -21.19134 1.000 12.26721  ?  341 PHE A HA   1 
ATOM   4045 H HB2  . PHE A 1 260 ? 24.71262  -16.57992 -24.25042 1.000 12.54412  ?  341 PHE A HB2  1 
ATOM   4046 H HB3  . PHE A 1 260 ? 24.06309  -15.18842 -23.33897 1.000 12.54412  ?  341 PHE A HB3  1 
ATOM   4047 H HD1  . PHE A 1 260 ? 27.14049  -17.20695 -23.82255 1.000 17.53645  ?  341 PHE A HD1  1 
ATOM   4048 H HD2  . PHE A 1 260 ? 25.45413  -13.46937 -22.71694 1.000 14.11701  ?  341 PHE A HD2  1 
ATOM   4049 H HE1  . PHE A 1 260 ? 29.41038  -16.23825 -23.62608 1.000 19.26612  ?  341 PHE A HE1  1 
ATOM   4050 H HE2  . PHE A 1 260 ? 27.70579  -12.49081 -22.62826 1.000 16.36104  ?  341 PHE A HE2  1 
ATOM   4051 H HZ   . PHE A 1 260 ? 29.66482  -13.84962 -23.10925 1.000 18.61556  ?  341 PHE A HZ   1 
ATOM   4052 N N    . ILE A 1 261 ? 22.16447  -16.38311 -21.65526 1.000 9.27535   ?  342 ILE A N    1 
ATOM   4053 C CA   . ILE A 1 261 ? 20.72523  -16.29271 -21.90540 1.000 9.41939   ?  342 ILE A CA   1 
ATOM   4054 C C    . ILE A 1 261 ? 20.42345  -14.87220 -22.35075 1.000 9.85186   ?  342 ILE A C    1 
ATOM   4055 O O    . ILE A 1 261 ? 21.10121  -13.91763 -21.95447 1.000 11.69832  ?  342 ILE A O    1 
ATOM   4056 C CB   . ILE A 1 261 ? 19.83620  -16.74695 -20.74388 1.000 10.21991  ?  342 ILE A CB   1 
ATOM   4057 C CG1  . ILE A 1 261 ? 20.09574  -15.87966 -19.49357 1.000 10.64615  ?  342 ILE A CG1  1 
ATOM   4058 C CG2  . ILE A 1 261 ? 20.15570  -18.21192 -20.42942 1.000 11.95691  ?  342 ILE A CG2  1 
ATOM   4059 C CD1  . ILE A 1 261 ? 19.13561  -16.17864 -18.36297 1.000 11.86768  ?  342 ILE A CD1  1 
ATOM   4060 H H    A ILE A 1 261 ? 22.49144  -15.68307 -20.98935 0.933 11.13042  ?  342 ILE A H    1 
ATOM   4061 D D    B ILE A 1 261 ? 22.49321  -15.68374 -20.98951 0.067 11.13042  ?  342 ILE A D    1 
ATOM   4062 H HA   . ILE A 1 261 ? 20.47215  -16.97559 -22.71640 1.000 11.30327  ?  342 ILE A HA   1 
ATOM   4063 H HB   . ILE A 1 261 ? 18.78940  -16.63780 -21.02742 1.000 12.26389  ?  342 ILE A HB   1 
ATOM   4064 H HG12 . ILE A 1 261 ? 21.10780  -16.06794 -19.13524 1.000 12.77538  ?  342 ILE A HG12 1 
ATOM   4065 H HG13 . ILE A 1 261 ? 19.98455  -14.82897 -19.76150 1.000 12.77538  ?  342 ILE A HG13 1 
ATOM   4066 H HG21 . ILE A 1 261 ? 19.88608  -18.82624 -21.28850 1.000 14.34830  ?  342 ILE A HG21 1 
ATOM   4067 H HG22 . ILE A 1 261 ? 21.22215  -18.30654 -20.22486 1.000 14.34830  ?  342 ILE A HG22 1 
ATOM   4068 H HG23 . ILE A 1 261 ? 19.58091  -18.52100 -19.55639 1.000 14.34830  ?  342 ILE A HG23 1 
ATOM   4069 H HD11 . ILE A 1 261 ? 19.59788  -15.88972 -17.41907 1.000 14.24122  ?  342 ILE A HD11 1 
ATOM   4070 H HD12 . ILE A 1 261 ? 18.21824  -15.61044 -18.51684 1.000 14.24122  ?  342 ILE A HD12 1 
ATOM   4071 H HD13 . ILE A 1 261 ? 18.91518  -17.24610 -18.35751 1.000 14.24122  ?  342 ILE A HD13 1 
ATOM   4072 N N    . VAL A 1 262 ? 19.41065  -14.73227 -23.20506 1.000 9.68610   ?  343 VAL A N    1 
ATOM   4073 C CA   . VAL A 1 262 ? 19.08762  -13.45233 -23.83225 1.000 9.76928   ?  343 VAL A CA   1 
ATOM   4074 C C    . VAL A 1 262 ? 17.60382  -13.18268 -23.67111 1.000 8.31863   ?  343 VAL A C    1 
ATOM   4075 O O    . VAL A 1 262 ? 16.77142  -13.97885 -24.11878 1.000 10.03009  ?  343 VAL A O    1 
ATOM   4076 C CB   . VAL A 1 262 ? 19.48993  -13.43189 -25.31500 1.000 10.42783  ?  343 VAL A CB   1 
ATOM   4077 C CG1  . VAL A 1 262 ? 19.23576  -12.09435 -25.93863 1.000 12.88906  ?  343 VAL A CG1  1 
ATOM   4078 C CG2  . VAL A 1 262 ? 20.94797  -13.80360 -25.47082 1.000 13.83450  ?  343 VAL A CG2  1 
ATOM   4079 H H    A VAL A 1 262 ? 18.79195  -15.49383 -23.48371 1.000 11.62332  ?  343 VAL A H    1 
ATOM   4080 D D    B VAL A 1 262 ? 18.79314  -15.49530 -23.48232 0.000 11.62332  ?  343 VAL A D    1 
ATOM   4081 H HA   . VAL A 1 262 ? 19.61978  -12.65650 -23.31115 1.000 11.72314  ?  343 VAL A HA   1 
ATOM   4082 H HB   . VAL A 1 262 ? 18.87627  -14.16535 -25.83804 1.000 12.51340  ?  343 VAL A HB   1 
ATOM   4083 H HG11 . VAL A 1 262 ? 18.18115  -11.84392 -25.82386 1.000 15.46687  ?  343 VAL A HG11 1 
ATOM   4084 H HG12 . VAL A 1 262 ? 19.85182  -11.34690 -25.43874 1.000 15.46687  ?  343 VAL A HG12 1 
ATOM   4085 H HG13 . VAL A 1 262 ? 19.49363  -12.14133 -26.99665 1.000 15.46687  ?  343 VAL A HG13 1 
ATOM   4086 H HG21 . VAL A 1 262 ? 21.26863  -14.35937 -24.58969 1.000 16.60140  ?  343 VAL A HG21 1 
ATOM   4087 H HG22 . VAL A 1 262 ? 21.06362  -14.42062 -26.36190 1.000 16.60140  ?  343 VAL A HG22 1 
ATOM   4088 H HG23 . VAL A 1 262 ? 21.53779  -12.89241 -25.57055 1.000 16.60140  ?  343 VAL A HG23 1 
ATOM   4089 N N    . ASP A 1 263 ? 17.26188  -12.02747 -23.11034 1.000 9.49254   ?  344 ASP A N    1 
ATOM   4090 C CA   . ASP A 1 263 ? 15.86412  -11.60434 -22.99554 1.000 9.31688   ?  344 ASP A CA   1 
ATOM   4091 C C    . ASP A 1 263 ? 15.38282  -11.14137 -24.36878 1.000 9.97580   ?  344 ASP A C    1 
ATOM   4092 O O    . ASP A 1 263 ? 16.05083  -10.33973 -25.00996 1.000 11.18094  ?  344 ASP A O    1 
ATOM   4093 C CB   . ASP A 1 263 ? 15.79124  -10.42231 -22.02969 1.000 8.87787   ?  344 ASP A CB   1 
ATOM   4094 C CG   . ASP A 1 263 ? 14.37126  -10.12049 -21.52371 1.000 10.72908  ?  344 ASP A CG   1 
ATOM   4095 O OD1  . ASP A 1 263 ? 13.41270  -10.69943 -22.01691 1.000 10.30761  ?  344 ASP A OD1  1 
ATOM   4096 O OD2  . ASP A 1 263 ? 14.29715  -9.32670  -20.55925 1.000 10.60356  -1 344 ASP A OD2  1 
ATOM   4097 H H    A ASP A 1 263 ? 17.92691  -11.35765 -22.72372 0.982 11.39105  ?  344 ASP A H    1 
ATOM   4098 D D    B ASP A 1 263 ? 17.92582  -11.35678 -22.72336 0.018 11.39105  ?  344 ASP A D    1 
ATOM   4099 H HA   . ASP A 1 263 ? 15.23745  -12.41963 -22.63404 1.000 11.18026  ?  344 ASP A HA   1 
ATOM   4100 H HB2  . ASP A 1 263 ? 16.41365  -10.63991 -21.16173 1.000 10.65345  ?  344 ASP A HB2  1 
ATOM   4101 H HB3  . ASP A 1 263 ? 16.15892  -9.53098  -22.53806 1.000 10.65345  ?  344 ASP A HB3  1 
ATOM   4102 N N    . GLN A 1 264 ? 14.24509  -11.66346 -24.83694 1.000 9.78423   ?  345 GLN A N    1 
ATOM   4103 C CA   . GLN A 1 264 ? 13.63295  -11.21170 -26.07038 1.000 10.05508  ?  345 GLN A CA   1 
ATOM   4104 C C    . GLN A 1 264 ? 12.17534  -10.84019 -25.83668 1.000 12.59055  ?  345 GLN A C    1 
ATOM   4105 O O    . GLN A 1 264 ? 11.43091  -10.67423 -26.80347 1.000 12.40549  ?  345 GLN A O    1 
ATOM   4106 C CB   . GLN A 1 264 ? 13.76689  -12.26702 -27.16195 1.000 10.70768  ?  345 GLN A CB   1 
ATOM   4107 C CG   . GLN A 1 264 ? 15.19240  -12.42692 -27.70205 1.000 12.11748  ?  345 GLN A CG   1 
ATOM   4108 C CD   . GLN A 1 264 ? 15.61858  -11.25185 -28.56494 1.000 13.43776  ?  345 GLN A CD   1 
ATOM   4109 O OE1  . GLN A 1 264 ? 15.22151  -11.16275 -29.75464 1.000 14.65094  ?  345 GLN A OE1  1 
ATOM   4110 N NE2  . GLN A 1 264 ? 16.40293  -10.36328 -28.01985 1.000 13.02000  ?  345 GLN A NE2  1 
ATOM   4111 H H    A GLN A 1 264 ? 13.72594  -12.40823 -24.37195 1.000 11.74107  ?  345 GLN A H    1 
ATOM   4112 D D    B GLN A 1 264 ? 13.72651  -12.40825 -24.37135 0.000 11.74107  ?  345 GLN A D    1 
ATOM   4113 H HA   . GLN A 1 264 ? 14.14941  -10.32317 -26.43355 1.000 12.06609  ?  345 GLN A HA   1 
ATOM   4114 H HB2  . GLN A 1 264 ? 13.45556  -13.22997 -26.75709 1.000 12.84922  ?  345 GLN A HB2  1 
ATOM   4115 H HB3  . GLN A 1 264 ? 13.12477  -11.98879 -27.99764 1.000 12.84922  ?  345 GLN A HB3  1 
ATOM   4116 H HG2  . GLN A 1 264 ? 15.88540  -12.50093 -26.86397 1.000 14.54098  ?  345 GLN A HG2  1 
ATOM   4117 H HG3  . GLN A 1 264 ? 15.24457  -13.33025 -28.30982 1.000 14.54098  ?  345 GLN A HG3  1 
ATOM   4118 N N    . GLY A 1 265 ? 11.75407  -10.67017 -24.56753 1.000 10.31316  ?  346 GLY A N    1 
ATOM   4119 C CA   . GLY A 1 265 ? 10.33882  -10.45457 -24.28603 1.000 12.15323  ?  346 GLY A CA   1 
ATOM   4120 C C    . GLY A 1 265 ? 9.74772   -9.20709  -24.91527 1.000 12.46093  ?  346 GLY A C    1 
ATOM   4121 O O    . GLY A 1 265 ? 8.56475   -9.20903  -25.27281 1.000 14.90088  ?  346 GLY A O    1 
ATOM   4122 H H    A GLY A 1 265 ? 12.35648  -10.67775 -23.74446 0.804 12.37579  ?  346 GLY A H    1 
ATOM   4123 D D    B GLY A 1 265 ? 12.35414  -10.67728 -23.74274 0.196 12.37579  ?  346 GLY A D    1 
ATOM   4124 H HA2  . GLY A 1 265 ? 9.77440   -11.31141 -24.65393 1.000 14.58387  ?  346 GLY A HA2  1 
ATOM   4125 H HA3  . GLY A 1 265 ? 10.20440  -10.37785 -23.20708 1.000 14.58387  ?  346 GLY A HA3  1 
ATOM   4126 N N    . ARG A 1 266 ? 10.52844  -8.18085  -25.12545 1.000 10.82506  ?  347 ARG A N    1 
ATOM   4127 C CA   . ARG A 1 266 ? 10.05668  -6.93091  -25.74963 1.000 11.61468  ?  347 ARG A CA   1 
ATOM   4128 C C    . ARG A 1 266 ? 10.84534  -6.56967  -27.00161 1.000 11.29101  ?  347 ARG A C    1 
ATOM   4129 O O    . ARG A 1 266 ? 10.97919  -5.39739  -27.32246 1.000 12.68266  ?  347 ARG A O    1 
ATOM   4130 C CB   . ARG A 1 266 ? 10.07199  -5.76903  -24.74513 1.000 11.13329  ?  347 ARG A CB   1 
ATOM   4131 C CG   . ARG A 1 266 ? 9.13240   -6.05892  -23.57272 1.000 13.77772  ?  347 ARG A CG   1 
ATOM   4132 C CD   . ARG A 1 266 ? 8.90151   -4.80580  -22.71743 1.000 13.64754  ?  347 ARG A CD   1 
ATOM   4133 N NE   . ARG A 1 266 ? 10.11202  -4.37402  -22.04854 1.000 12.08693  ?  347 ARG A NE   1 
ATOM   4134 C CZ   . ARG A 1 266 ? 10.20331  -3.27069  -21.31432 1.000 13.71892  ?  347 ARG A CZ   1 
ATOM   4135 N NH1  . ARG A 1 266 ? 9.14576   -2.50315  -21.07367 1.000 15.42904  ?  347 ARG A NH1  1 
ATOM   4136 N NH2  . ARG A 1 266 ? 11.36496  -2.93000  -20.79103 1.000 12.50192  ?  347 ARG A NH2  1 
ATOM   4137 H H    A ARG A 1 266 ? 11.51758  -8.16158  -24.87719 0.506 12.99007  ?  347 ARG A H    1 
ATOM   4138 D D    B ARG A 1 266 ? 11.51743  -8.16347  -24.87647 0.494 12.99007  ?  347 ARG A D    1 
ATOM   4139 H HA   . ARG A 1 266 ? 9.02430   -7.09141  -26.06032 1.000 13.93762  ?  347 ARG A HA   1 
ATOM   4140 H HB2  . ARG A 1 266 ? 11.08190  -5.63666  -24.35696 1.000 13.35995  ?  347 ARG A HB2  1 
ATOM   4141 H HB3  . ARG A 1 266 ? 9.73994   -4.85606  -25.23942 1.000 13.35995  ?  347 ARG A HB3  1 
ATOM   4142 H HG2  . ARG A 1 266 ? 8.16896   -6.39495  -23.95608 1.000 16.53326  ?  347 ARG A HG2  1 
ATOM   4143 H HG3  . ARG A 1 266 ? 9.57134   -6.83019  -22.93980 1.000 16.53326  ?  347 ARG A HG3  1 
ATOM   4144 H HD2  . ARG A 1 266 ? 8.55794   -3.99314  -23.35746 1.000 16.37705  ?  347 ARG A HD2  1 
ATOM   4145 H HD3  . ARG A 1 266 ? 8.15172   -5.02388  -21.95693 1.000 16.37705  ?  347 ARG A HD3  1 
ATOM   4146 N N    . SER A 1 267 ? 11.31230  -7.57065  -27.73749 1.000 11.72549  ?  348 SER A N    1 
ATOM   4147 C CA   . SER A 1 267 ? 12.19718  -7.38032  -28.87390 1.000 12.45332  ?  348 SER A CA   1 
ATOM   4148 C C    . SER A 1 267 ? 11.52206  -7.61116  -30.21876 1.000 12.63078  ?  348 SER A C    1 
ATOM   4149 O O    . SER A 1 267 ? 12.20792  -7.62590  -31.24385 1.000 13.93442  ?  348 SER A O    1 
ATOM   4150 C CB   . SER A 1 267 ? 13.44501  -8.26899  -28.74038 1.000 13.21828  ?  348 SER A CB   1 
ATOM   4151 O OG   . SER A 1 267 ? 14.20296  -7.84250  -27.62868 1.000 13.57335  ?  348 SER A OG   1 
ATOM   4152 H H    A SER A 1 267 ? 11.08783  -8.55048  -27.56440 0.956 14.07059  ?  348 SER A H    1 
ATOM   4153 D D    B SER A 1 267 ? 11.08686  -8.55002  -27.56308 0.044 14.07059  ?  348 SER A D    1 
ATOM   4154 H HA   . SER A 1 267 ? 12.52610  -6.34119  -28.86283 1.000 14.94398  ?  348 SER A HA   1 
ATOM   4155 H HB2  . SER A 1 267 ? 13.13794  -9.30446  -28.59338 1.000 15.86193  ?  348 SER A HB2  1 
ATOM   4156 H HB3  . SER A 1 267 ? 14.04846  -8.18381  -29.64409 1.000 15.86193  ?  348 SER A HB3  1 
ATOM   4157 N N    . GLY A 1 268 ? 10.21264  -7.77993  -30.23926 1.000 13.11654  ?  349 GLY A N    1 
ATOM   4158 C CA   . GLY A 1 268 ? 9.53323   -8.14549  -31.49916 1.000 16.20825  ?  349 GLY A CA   1 
ATOM   4159 C C    . GLY A 1 268 ? 9.60723   -7.06781  -32.56420 1.000 16.83947  ?  349 GLY A C    1 
ATOM   4160 O O    . GLY A 1 268 ? 9.58385   -7.39011  -33.76257 1.000 18.14644  ?  349 GLY A O    1 
ATOM   4161 H H    A GLY A 1 268 ? 9.59531   -7.67810  -29.43370 0.779 15.73985  ?  349 GLY A H    1 
ATOM   4162 D D    B GLY A 1 268 ? 9.59300   -7.67876  -29.43539 0.221 15.73985  ?  349 GLY A D    1 
ATOM   4163 H HA2  . GLY A 1 268 ? 9.99167   -9.04925  -31.90061 1.000 19.44990  ?  349 GLY A HA2  1 
ATOM   4164 H HA3  . GLY A 1 268 ? 8.48169   -8.34329  -31.29118 1.000 19.44990  ?  349 GLY A HA3  1 
ATOM   4165 N N    . VAL A 1 269 ? 9.69042   -5.80503  -32.15723 1.000 14.19705  ?  350 VAL A N    1 
ATOM   4166 C CA   . VAL A 1 269 ? 9.65894   -4.65767  -33.05688 1.000 16.19849  ?  350 VAL A CA   1 
ATOM   4167 C C    . VAL A 1 269 ? 10.95243  -3.89081  -32.89355 1.000 14.93228  ?  350 VAL A C    1 
ATOM   4168 O O    . VAL A 1 269 ? 11.27266  -3.43423  -31.79862 1.000 14.95590  ?  350 VAL A O    1 
ATOM   4169 C CB   . VAL A 1 269 ? 8.43332   -3.75633  -32.77427 1.000 16.08175  ?  350 VAL A CB   1 
ATOM   4170 C CG1  . VAL A 1 269 ? 8.39255   -2.59204  -33.75679 1.000 20.24346  ?  350 VAL A CG1  1 
ATOM   4171 C CG2  . VAL A 1 269 ? 7.14403   -4.57345  -32.86089 1.000 17.58050  ?  350 VAL A CG2  1 
ATOM   4172 H H    A VAL A 1 269 ? 9.78341   -5.53738  -31.17738 0.801 17.03646  ?  350 VAL A H    1 
ATOM   4173 D D    B VAL A 1 269 ? 9.78337   -5.53993  -31.17668 0.199 17.03646  ?  350 VAL A D    1 
ATOM   4174 H HA   . VAL A 1 269 ? 9.60687   -5.00394  -34.08911 1.000 19.43819  ?  350 VAL A HA   1 
ATOM   4175 H HB   . VAL A 1 269 ? 8.51598   -3.34989  -31.76626 1.000 19.29810  ?  350 VAL A HB   1 
ATOM   4176 H HG11 . VAL A 1 269 ? 7.74557   -1.81182  -33.35581 1.000 24.29215  ?  350 VAL A HG11 1 
ATOM   4177 H HG12 . VAL A 1 269 ? 9.40270   -2.20497  -33.89048 1.000 24.29215  ?  350 VAL A HG12 1 
ATOM   4178 H HG13 . VAL A 1 269 ? 8.00089   -2.94600  -34.71042 1.000 24.29215  ?  350 VAL A HG13 1 
ATOM   4179 H HG21 . VAL A 1 269 ? 6.81993   -4.83289  -31.85305 1.000 21.09660  ?  350 VAL A HG21 1 
ATOM   4180 H HG22 . VAL A 1 269 ? 6.37797   -3.97627  -33.35550 1.000 21.09660  ?  350 VAL A HG22 1 
ATOM   4181 H HG23 . VAL A 1 269 ? 7.33639   -5.48016  -33.43444 1.000 21.09660  ?  350 VAL A HG23 1 
ATOM   4182 N N    . GLN A 1 270 ? 11.68504  -3.73204  -33.99025 1.000 16.05773  ?  351 GLN A N    1 
ATOM   4183 C CA   . GLN A 1 270 ? 12.93775  -3.00443  -33.99477 1.000 13.56782  ?  351 GLN A CA   1 
ATOM   4184 C C    . GLN A 1 270 ? 12.71890  -1.61922  -34.58698 1.000 17.25673  ?  351 GLN A C    1 
ATOM   4185 O O    . GLN A 1 270 ? 11.63419  -1.30463  -35.09649 1.000 17.74062  ?  351 GLN A O    1 
ATOM   4186 C CB   . GLN A 1 270 ? 13.95138  -3.77192  -34.82708 1.000 15.42155  ?  351 GLN A CB   1 
ATOM   4187 C CG   . GLN A 1 270 ? 14.25434  -5.13764  -34.19845 1.000 17.29134  ?  351 GLN A CG   1 
ATOM   4188 C CD   . GLN A 1 270 ? 14.90953  -4.96928  -32.82979 1.000 13.89980  ?  351 GLN A CD   1 
ATOM   4189 O OE1  . GLN A 1 270 ? 15.88256  -4.27544  -32.68519 1.000 15.80622  ?  351 GLN A OE1  1 
ATOM   4190 N NE2  . GLN A 1 270 ? 14.28739  -5.58217  -31.79609 1.000 14.99780  ?  351 GLN A NE2  1 
ATOM   4191 H H    A GLN A 1 270 ? 11.42735  -4.10475  -34.90407 0.684 19.26928  ?  351 GLN A H    1 
ATOM   4192 D D    B GLN A 1 270 ? 11.42584  -4.10545  -34.90336 0.316 19.26928  ?  351 GLN A D    1 
ATOM   4193 H HA   . GLN A 1 270 ? 13.31949  -2.89246  -32.97996 1.000 16.28138  ?  351 GLN A HA   1 
ATOM   4194 H HB2  . GLN A 1 270 ? 13.55133  -3.93263  -35.82819 1.000 18.50585  ?  351 GLN A HB2  1 
ATOM   4195 H HB3  . GLN A 1 270 ? 14.87950  -3.20312  -34.88337 1.000 18.50585  ?  351 GLN A HB3  1 
ATOM   4196 H HG2  . GLN A 1 270 ? 13.32566  -5.69413  -34.07209 1.000 20.74960  ?  351 GLN A HG2  1 
ATOM   4197 H HG3  . GLN A 1 270 ? 14.93626  -5.69187  -34.84337 1.000 20.74960  ?  351 GLN A HG3  1 
ATOM   4198 N N    . ASN A 1 271 ? 13.74138  -0.78471  -34.48188 1.000 15.54151  ?  352 ASN A N    1 
ATOM   4199 C CA   . ASN A 1 271 ? 13.75220  0.56082   -35.07449 1.000 16.10919  ?  352 ASN A CA   1 
ATOM   4200 C C    . ASN A 1 271 ? 12.62558  1.41044   -34.51573 1.000 26.27135  ?  352 ASN A C    1 
ATOM   4201 O O    . ASN A 1 271 ? 11.89569  2.07557   -35.25465 1.000 22.35024  ?  352 ASN A O    1 
ATOM   4202 C CB   . ASN A 1 271 ? 13.62310  0.47602   -36.59680 1.000 22.48941  ?  352 ASN A CB   1 
ATOM   4203 C CG   . ASN A 1 271 ? 14.75058  -0.26393  -37.25548 1.000 20.14213  ?  352 ASN A CG   1 
ATOM   4204 O OD1  . ASN A 1 271 ? 15.61076  -0.85157  -36.61313 1.000 22.01814  ?  352 ASN A OD1  1 
ATOM   4205 N ND2  . ASN A 1 271 ? 14.76189  -0.23463  -38.58563 1.000 28.94473  ?  352 ASN A ND2  1 
ATOM   4206 H H    A ASN A 1 271 ? 14.60222  -1.00770  -33.98226 0.765 18.64982  ?  352 ASN A H    1 
ATOM   4207 D D    B ASN A 1 271 ? 14.60177  -1.00880  -33.98198 0.235 18.64982  ?  352 ASN A D    1 
ATOM   4208 H HA   . ASN A 1 271 ? 14.69887  1.03747   -34.82011 1.000 19.33103  ?  352 ASN A HA   1 
ATOM   4209 H HB2  . ASN A 1 271 ? 12.69620  -0.04217  -36.84264 1.000 26.98729  ?  352 ASN A HB2  1 
ATOM   4210 H HB3  . ASN A 1 271 ? 13.60475  1.48660   -37.00484 1.000 26.98729  ?  352 ASN A HB3  1 
ATOM   4211 N N    . ILE A 1 272 ? 12.46928  1.37385   -33.19292 1.000 20.27972  ?  353 ILE A N    1 
ATOM   4212 C CA   . ILE A 1 272 ? 11.44409  2.15662   -32.50844 1.000 18.00724  ?  353 ILE A CA   1 
ATOM   4213 C C    . ILE A 1 272 ? 12.03158  3.17195   -31.53723 1.000 19.56248  ?  353 ILE A C    1 
ATOM   4214 O O    . ILE A 1 272 ? 11.27751  3.88884   -30.86627 1.000 23.27984  ?  353 ILE A O    1 
ATOM   4215 C CB   . ILE A 1 272 ? 10.38542  1.27657   -31.81026 1.000 19.76509  ?  353 ILE A CB   1 
ATOM   4216 C CG1  . ILE A 1 272 ? 11.06060  0.20451   -30.94392 1.000 20.59734  ?  353 ILE A CG1  1 
ATOM   4217 C CG2  . ILE A 1 272 ? 9.45687   0.64979   -32.84349 1.000 26.79744  ?  353 ILE A CG2  1 
ATOM   4218 C CD1  . ILE A 1 272 ? 10.12546  -0.48337  -30.04521 1.000 21.91076  ?  353 ILE A CD1  1 
ATOM   4219 H H    A ILE A 1 272 ? 13.04161  0.80778   -32.56650 0.710 24.33566  ?  353 ILE A H    1 
ATOM   4220 D D    B ILE A 1 272 ? 13.04259  0.80714   -32.56797 0.290 24.33566  ?  353 ILE A D    1 
ATOM   4221 H HA   . ILE A 1 272 ? 10.90743  2.72097   -33.27106 1.000 21.60869  ?  353 ILE A HA   1 
ATOM   4222 H HB   . ILE A 1 272 ? 9.78719   1.90673   -31.15215 1.000 23.71810  ?  353 ILE A HB   1 
ATOM   4223 H HG12 . ILE A 1 272 ? 11.51177  -0.54371  -31.59561 1.000 24.71681  ?  353 ILE A HG12 1 
ATOM   4224 H HG13 . ILE A 1 272 ? 11.82846  0.67725   -30.33154 1.000 24.71681  ?  353 ILE A HG13 1 
ATOM   4225 H HG21 . ILE A 1 272 ? 9.25120   -0.38144  -32.55652 1.000 32.15693  ?  353 ILE A HG21 1 
ATOM   4226 H HG22 . ILE A 1 272 ? 8.52770   1.21867   -32.87699 1.000 32.15693  ?  353 ILE A HG22 1 
ATOM   4227 H HG23 . ILE A 1 272 ? 9.94307   0.67431   -33.81874 1.000 32.15693  ?  353 ILE A HG23 1 
ATOM   4228 H HD11 . ILE A 1 272 ? 9.43516   -1.08062  -30.64092 1.000 26.29291  ?  353 ILE A HD11 1 
ATOM   4229 H HD12 . ILE A 1 272 ? 10.68990  -1.12872  -29.37214 1.000 26.29291  ?  353 ILE A HD12 1 
ATOM   4230 H HD13 . ILE A 1 272 ? 9.57319   0.26042   -29.47085 1.000 26.29291  ?  353 ILE A HD13 1 
ATOM   4231 N N    . ARG A 1 273 ? 13.33914  3.25557   -31.42442 1.000 18.17650  ?  354 ARG A N    1 
ATOM   4232 C CA   . ARG A 1 273 ? 13.96616  4.14458   -30.48278 1.000 16.84637  ?  354 ARG A CA   1 
ATOM   4233 C C    . ARG A 1 273 ? 14.66756  5.27706   -31.21431 1.000 21.73563  ?  354 ARG A C    1 
ATOM   4234 O O    . ARG A 1 273 ? 15.16678  5.11273   -32.33139 1.000 21.14077  ?  354 ARG A O    1 
ATOM   4235 C CB   . ARG A 1 273 ? 15.00820  3.40934   -29.61915 1.000 17.13214  ?  354 ARG A CB   1 
ATOM   4236 C CG   . ARG A 1 273 ? 14.40172  2.53924   -28.51840 1.000 17.48592  ?  354 ARG A CG   1 
ATOM   4237 C CD   . ARG A 1 273 ? 15.43338  1.74398   -27.78476 1.000 14.66023  ?  354 ARG A CD   1 
ATOM   4238 N NE   . ARG A 1 273 ? 15.89338  0.61882   -28.56644 1.000 15.31021  ?  354 ARG A NE   1 
ATOM   4239 C CZ   . ARG A 1 273 ? 16.71180  -0.34500  -28.12666 1.000 15.40392  ?  354 ARG A CZ   1 
ATOM   4240 N NH1  . ARG A 1 273 ? 17.22309  -0.30042  -26.91643 1.000 19.17710  ?  354 ARG A NH1  1 
ATOM   4241 N NH2  . ARG A 1 273 ? 17.03754  -1.34319  -28.94475 1.000 16.07999  ?  354 ARG A NH2  1 
ATOM   4242 H H    A ARG A 1 273 ? 13.99707  2.71048   -31.98156 0.699 21.81181  ?  354 ARG A H    1 
ATOM   4243 D D    B ARG A 1 273 ? 13.99544  2.70954   -31.98257 0.301 21.81181  ?  354 ARG A D    1 
ATOM   4244 H HA   . ARG A 1 273 ? 13.19561  4.55820   -29.83218 1.000 20.21565  ?  354 ARG A HA   1 
ATOM   4245 H HB2  . ARG A 1 273 ? 15.60206  2.76177   -30.26419 1.000 20.55857  ?  354 ARG A HB2  1 
ATOM   4246 H HB3  . ARG A 1 273 ? 15.65011  4.14922   -29.14099 1.000 20.55857  ?  354 ARG A HB3  1 
ATOM   4247 H HG2  . ARG A 1 273 ? 13.89268  3.17907   -27.79757 1.000 20.98310  ?  354 ARG A HG2  1 
ATOM   4248 H HG3  . ARG A 1 273 ? 13.69222  1.84239   -28.96462 1.000 20.98310  ?  354 ARG A HG3  1 
ATOM   4249 H HD2  . ARG A 1 273 ? 16.29007  2.38097   -27.56472 1.000 17.59227  ?  354 ARG A HD2  1 
ATOM   4250 H HD3  . ARG A 1 273 ? 15.00354  1.36400   -26.85796 1.000 17.59227  ?  354 ARG A HD3  1 
ATOM   4251 N N    . GLN A 1 274 ? 14.67672  6.43946   -30.57180 1.000 19.29128  ?  355 GLN A N    1 
ATOM   4252 C CA   A GLN A 1 274 ? 15.36890  7.60028   -31.11531 0.515 22.19999  ?  355 GLN A CA   1 
ATOM   4253 C CA   B GLN A 1 274 ? 15.38146  7.58080   -31.13756 0.485 22.14719  ?  355 GLN A CA   1 
ATOM   4254 C C    . GLN A 1 274 ? 16.85142  7.57586   -30.77595 1.000 22.64886  ?  355 GLN A C    1 
ATOM   4255 O O    . GLN A 1 274 ? 17.68473  7.98993   -31.59338 1.000 28.34466  ?  355 GLN A O    1 
ATOM   4256 C CB   A GLN A 1 274 ? 14.73775  8.89432   -30.58067 0.515 26.49813  ?  355 GLN A CB   1 
ATOM   4257 C CB   B GLN A 1 274 ? 14.68840  8.87653   -30.70013 0.485 26.56656  ?  355 GLN A CB   1 
ATOM   4258 C CG   A GLN A 1 274 ? 15.66002  10.11176  -30.70797 0.515 30.01372  ?  355 GLN A CG   1 
ATOM   4259 C CG   B GLN A 1 274 ? 13.30202  9.01687   -31.30531 0.485 26.51791  ?  355 GLN A CG   1 
ATOM   4260 C CD   A GLN A 1 274 ? 14.91815  11.42136  -30.54898 0.515 38.65640  ?  355 GLN A CD   1 
ATOM   4261 C CD   B GLN A 1 274 ? 12.51778  10.17591  -30.73483 0.485 38.33374  ?  355 GLN A CD   1 
ATOM   4262 O OE1  A GLN A 1 274 ? 15.22967  12.23432  -29.66848 0.515 26.87880  ?  355 GLN A OE1  1 
ATOM   4263 O OE1  B GLN A 1 274 ? 11.57587  10.66458  -31.35891 0.485 43.47408  ?  355 GLN A OE1  1 
ATOM   4264 N NE2  A GLN A 1 274 ? 13.92660  11.63449  -31.40284 0.515 38.98733  ?  355 GLN A NE2  1 
ATOM   4265 N NE2  B GLN A 1 274 ? 12.89433  10.62142  -29.53574 0.485 43.58793  ?  355 GLN A NE2  1 
ATOM   4266 H H    A GLN A 1 274 ? 14.21687  6.60982   -29.67741 0.719 23.14954  ?  355 GLN A H    1 
ATOM   4267 D D    B GLN A 1 274 ? 14.21643  6.61775   -29.67919 0.281 23.14954  ?  355 GLN A D    1 
ATOM   4268 H HA   A GLN A 1 274 ? 15.26064  7.58776   -32.19985 0.515 26.63999  ?  355 GLN A HA   1 
ATOM   4269 H HA   B GLN A 1 274 ? 15.33279  7.56022   -32.22628 0.485 26.57663  ?  355 GLN A HA   1 
ATOM   4270 H HB2  A GLN A 1 274 ? 13.82786  9.10213   -31.14371 0.515 31.79775  ?  355 GLN A HB2  1 
ATOM   4271 H HB2  B GLN A 1 274 ? 14.58797  8.87925   -29.61477 0.485 31.87988  ?  355 GLN A HB2  1 
ATOM   4272 H HB3  A GLN A 1 274 ? 14.50081  8.76159   -29.52505 0.515 31.79775  ?  355 GLN A HB3  1 
ATOM   4273 H HB3  B GLN A 1 274 ? 15.28785  9.72840   -31.02119 0.485 31.87988  ?  355 GLN A HB3  1 
ATOM   4274 H HG2  A GLN A 1 274 ? 16.42568  10.06091  -29.93384 0.515 36.01647  ?  355 GLN A HG2  1 
ATOM   4275 H HG2  B GLN A 1 274 ? 13.39975  9.17497   -32.37934 0.485 31.82149  ?  355 GLN A HG2  1 
ATOM   4276 H HG3  A GLN A 1 274 ? 16.12536  10.10442  -31.69362 0.515 36.01647  ?  355 GLN A HG3  1 
ATOM   4277 H HG3  B GLN A 1 274 ? 12.73840  8.10401   -31.11263 0.485 31.82149  ?  355 GLN A HG3  1 
ATOM   4278 N N    . GLN A 1 275 ? 17.19981  7.09773   -29.58933 1.000 21.52466  ?  356 GLN A N    1 
ATOM   4279 C CA   A GLN A 1 275 ? 18.59176  6.85849   -29.23413 0.489 18.76035  ?  356 GLN A CA   1 
ATOM   4280 C CA   B GLN A 1 275 ? 18.58096  6.89457   -29.16434 0.511 18.73283  ?  356 GLN A CA   1 
ATOM   4281 C C    . GLN A 1 275 ? 18.69495  5.53156   -28.48885 1.000 22.51822  ?  356 GLN A C    1 
ATOM   4282 O O    . GLN A 1 275 ? 17.72212  5.04684   -27.89762 1.000 19.10991  ?  356 GLN A O    1 
ATOM   4283 C CB   A GLN A 1 275 ? 19.20387  8.01616   -28.43188 0.489 24.97299  ?  356 GLN A CB   1 
ATOM   4284 C CB   B GLN A 1 275 ? 19.03922  7.97510   -28.16843 0.511 24.88409  ?  356 GLN A CB   1 
ATOM   4285 C CG   A GLN A 1 275 ? 19.13100  9.40840   -29.12525 0.489 31.11543  ?  356 GLN A CG   1 
ATOM   4286 C CG   B GLN A 1 275 ? 19.67574  9.20898   -28.82143 0.511 37.43236  ?  356 GLN A CG   1 
ATOM   4287 C CD   A GLN A 1 275 ? 20.32098  9.71909   -30.05216 0.489 33.40900  ?  356 GLN A CD   1 
ATOM   4288 C CD   B GLN A 1 275 ? 20.27877  10.16671  -27.80934 0.511 29.87420  ?  356 GLN A CD   1 
ATOM   4289 O OE1  A GLN A 1 275 ? 21.38598  10.16837  -29.60535 0.489 29.32208  ?  356 GLN A OE1  1 
ATOM   4290 O OE1  B GLN A 1 275 ? 21.38500  10.68719  -27.99350 0.511 22.83843  ?  356 GLN A OE1  1 
ATOM   4291 N NE2  A GLN A 1 275 ? 20.12578  9.49535   -31.35111 0.489 29.21611  ?  356 GLN A NE2  1 
ATOM   4292 N NE2  B GLN A 1 275 ? 19.54107  10.40568  -26.73021 0.511 36.82781  ?  356 GLN A NE2  1 
ATOM   4293 H H    A GLN A 1 275 ? 16.53796  6.86503   -28.84892 0.813 25.82959  ?  356 GLN A H    1 
ATOM   4294 D D    B GLN A 1 275 ? 16.52319  6.83197   -28.87382 0.187 25.82959  ?  356 GLN A D    1 
ATOM   4295 H HA   A GLN A 1 275 ? 19.19237  6.76918   -30.13933 0.489 22.51242  ?  356 GLN A HA   1 
ATOM   4296 H HA   B GLN A 1 275 ? 19.23426  6.92762   -30.03624 0.511 22.47940  ?  356 GLN A HA   1 
ATOM   4297 H HB2  A GLN A 1 275 ? 18.67430  8.09581   -27.48251 0.489 29.96759  ?  356 GLN A HB2  1 
ATOM   4298 H HB2  B GLN A 1 275 ? 18.17327  8.31297   -27.59916 0.511 29.86091  ?  356 GLN A HB2  1 
ATOM   4299 H HB3  A GLN A 1 275 ? 20.25617  7.79424   -28.25430 0.489 29.96759  ?  356 GLN A HB3  1 
ATOM   4300 H HB3  B GLN A 1 275 ? 19.77905  7.53835   -27.49761 0.511 29.86091  ?  356 GLN A HB3  1 
ATOM   4301 H HG2  A GLN A 1 275 ? 18.22400  9.45012   -29.72834 0.489 37.33852  ?  356 GLN A HG2  1 
ATOM   4302 H HG2  B GLN A 1 275 ? 20.47061  8.88466   -29.49307 0.511 44.91883  ?  356 GLN A HG2  1 
ATOM   4303 H HG3  A GLN A 1 275 ? 19.10275  10.17976  -28.35563 0.489 37.33852  ?  356 GLN A HG3  1 
ATOM   4304 H HG3  B GLN A 1 275 ? 18.91151  9.74814   -29.38122 0.511 44.91883  ?  356 GLN A HG3  1 
ATOM   4305 N N    . TRP A 1 276 ? 19.87543  4.91528   -28.57501 1.000 17.26007  ?  357 TRP A N    1 
ATOM   4306 C CA   . TRP A 1 276 ? 20.06355  3.57259   -28.02099 1.000 19.32421  ?  357 TRP A CA   1 
ATOM   4307 C C    . TRP A 1 276 ? 19.85945  3.54211   -26.50707 1.000 20.18395  ?  357 TRP A C    1 
ATOM   4308 O O    . TRP A 1 276 ? 19.40416  2.52290   -25.96839 1.000 17.98237  ?  357 TRP A O    1 
ATOM   4309 C CB   . TRP A 1 276 ? 21.45990  3.00209   -28.34925 1.000 15.82906  ?  357 TRP A CB   1 
ATOM   4310 C CG   . TRP A 1 276 ? 21.49054  1.49986   -28.52080 1.000 13.74950  ?  357 TRP A CG   1 
ATOM   4311 C CD1  . TRP A 1 276 ? 20.51117  0.58517   -28.14045 1.000 14.76515  ?  357 TRP A CD1  1 
ATOM   4312 C CD2  . TRP A 1 276 ? 22.52802  0.74691   -29.12627 1.000 12.64940  ?  357 TRP A CD2  1 
ATOM   4313 N NE1  . TRP A 1 276 ? 20.90032  -0.68711  -28.48517 1.000 13.73111  ?  357 TRP A NE1  1 
ATOM   4314 C CE2  . TRP A 1 276 ? 22.13986  -0.60963  -29.09670 1.000 13.07824  ?  357 TRP A CE2  1 
ATOM   4315 C CE3  . TRP A 1 276 ? 23.75393  1.08232   -29.70313 1.000 14.95498  ?  357 TRP A CE3  1 
ATOM   4316 C CZ2  . TRP A 1 276 ? 22.94179  -1.61210  -29.63257 1.000 13.36049  ?  357 TRP A CZ2  1 
ATOM   4317 C CZ3  . TRP A 1 276 ? 24.55082  0.06851   -30.22225 1.000 14.24414  ?  357 TRP A CZ3  1 
ATOM   4318 C CH2  . TRP A 1 276 ? 24.12901  -1.25388  -30.17412 1.000 13.43883  ?  357 TRP A CH2  1 
ATOM   4319 H H    A TRP A 1 276 ? 20.70731  5.30992   -29.01391 0.699 20.71208  ?  357 TRP A H    1 
ATOM   4320 D D    B TRP A 1 276 ? 20.70869  5.30767   -29.01331 0.301 20.71208  ?  357 TRP A D    1 
ATOM   4321 H HA   . TRP A 1 276 ? 19.32105  2.93270   -28.49779 1.000 23.18905  ?  357 TRP A HA   1 
ATOM   4322 H HB2  . TRP A 1 276 ? 21.80881  3.44836   -29.28049 1.000 18.99488  ?  357 TRP A HB2  1 
ATOM   4323 H HB3  . TRP A 1 276 ? 22.14022  3.25594   -27.53634 1.000 18.99488  ?  357 TRP A HB3  1 
ATOM   4324 H HD1  . TRP A 1 276 ? 19.58392  0.83815   -27.64790 1.000 17.71818  ?  357 TRP A HD1  1 
ATOM   4325 H HE3  . TRP A 1 276 ? 24.07779  2.11175   -29.74544 1.000 17.94597  ?  357 TRP A HE3  1 
ATOM   4326 H HZ2  . TRP A 1 276 ? 22.62640  -2.64490  -29.61686 1.000 16.03259  ?  357 TRP A HZ2  1 
ATOM   4327 H HZ3  . TRP A 1 276 ? 25.50500  0.31095   -30.66628 1.000 17.09297  ?  357 TRP A HZ3  1 
ATOM   4328 H HH2  . TRP A 1 276 ? 24.76964  -2.02156  -30.58236 1.000 16.12659  ?  357 TRP A HH2  1 
ATOM   4329 N N    . GLY A 1 277 ? 20.17525  4.62512   -25.80637 1.000 18.40491  ?  358 GLY A N    1 
ATOM   4330 C CA   . GLY A 1 277 ? 20.03128  4.66298   -24.36572 1.000 17.46339  ?  358 GLY A CA   1 
ATOM   4331 C C    . GLY A 1 277 ? 18.60843  4.80640   -23.86336 1.000 16.62078  ?  358 GLY A C    1 
ATOM   4332 O O    . GLY A 1 277 ? 18.40712  4.72076   -22.64317 1.000 22.27338  ?  358 GLY A O    1 
ATOM   4333 H H    A GLY A 1 277 ? 20.53301  5.48944   -26.21299 0.610 22.08590  ?  358 GLY A H    1 
ATOM   4334 D D    B GLY A 1 277 ? 20.53298  5.48917   -26.21360 0.390 22.08590  ?  358 GLY A D    1 
ATOM   4335 H HA2  . GLY A 1 277 ? 20.43706  3.73994   -23.95166 1.000 20.95606  ?  358 GLY A HA2  1 
ATOM   4336 H HA3  . GLY A 1 277 ? 20.60466  5.50653   -23.98134 1.000 20.95606  ?  358 GLY A HA3  1 
ATOM   4337 N N    . ASP A 1 278 ? 17.62562  5.00647   -24.74026 1.000 15.52260  ?  359 ASP A N    1 
ATOM   4338 C CA   . ASP A 1 278 ? 16.23496  5.16981   -24.29994 1.000 16.06844  ?  359 ASP A CA   1 
ATOM   4339 C C    . ASP A 1 278 ? 15.67202  3.79445   -23.90414 1.000 17.09105  ?  359 ASP A C    1 
ATOM   4340 O O    . ASP A 1 278 ? 15.56118  2.89139   -24.76065 1.000 18.66597  ?  359 ASP A O    1 
ATOM   4341 C CB   . ASP A 1 278 ? 15.36568  5.72642   -25.43148 1.000 19.57051  ?  359 ASP A CB   1 
ATOM   4342 C CG   . ASP A 1 278 ? 15.83421  7.08769   -25.93241 1.000 21.79652  ?  359 ASP A CG   1 
ATOM   4343 O OD1  . ASP A 1 278 ? 16.72154  7.67167   -25.29079 1.000 22.64953  ?  359 ASP A OD1  1 
ATOM   4344 O OD2  . ASP A 1 278 ? 15.31409  7.51773   -26.97513 1.000 22.07762  -1 359 ASP A OD2  1 
ATOM   4345 H H    A ASP A 1 278 ? 17.75416  5.06046   -25.75069 0.681 18.62713  ?  359 ASP A H    1 
ATOM   4346 D D    B ASP A 1 278 ? 17.75332  5.06058   -25.75079 0.319 18.62713  ?  359 ASP A D    1 
ATOM   4347 H HA   . ASP A 1 278 ? 16.21570  5.86039   -23.45684 1.000 19.28213  ?  359 ASP A HA   1 
ATOM   4348 H HB2  . ASP A 1 278 ? 15.39227  5.03265   -26.27177 1.000 23.48461  ?  359 ASP A HB2  1 
ATOM   4349 H HB3  . ASP A 1 278 ? 14.34299  5.83583   -25.07059 1.000 23.48461  ?  359 ASP A HB3  1 
ATOM   4350 N N    . TRP A 1 279 ? 15.25528  3.65258   -22.65299 1.000 14.98945  ?  360 TRP A N    1 
ATOM   4351 C CA   . TRP A 1 279 ? 14.91424  2.34808   -22.11653 1.000 15.62037  ?  360 TRP A CA   1 
ATOM   4352 C C    . TRP A 1 279 ? 13.51860  2.26792   -21.53038 1.000 14.96900  ?  360 TRP A C    1 
ATOM   4353 O O    . TRP A 1 279 ? 13.06530  1.16323   -21.22924 1.000 14.68083  ?  360 TRP A O    1 
ATOM   4354 C CB   . TRP A 1 279 ? 15.91937  1.91561   -21.02751 1.000 14.76430  ?  360 TRP A CB   1 
ATOM   4355 C CG   . TRP A 1 279 ? 16.04736  2.93294   -19.97257 1.000 19.17429  ?  360 TRP A CG   1 
ATOM   4356 C CD1  . TRP A 1 279 ? 16.95408  3.94597   -19.92497 1.000 21.07248  ?  360 TRP A CD1  1 
ATOM   4357 C CD2  . TRP A 1 279 ? 15.20781  3.08844   -18.80360 1.000 22.29064  ?  360 TRP A CD2  1 
ATOM   4358 N NE1  . TRP A 1 279 ? 16.74967  4.71202   -18.79205 1.000 28.42770  ?  360 TRP A NE1  1 
ATOM   4359 C CE2  . TRP A 1 279 ? 15.68698  4.20413   -18.09127 1.000 25.23078  ?  360 TRP A CE2  1 
ATOM   4360 C CE3  . TRP A 1 279 ? 14.11325  2.37179   -18.28130 1.000 18.62296  ?  360 TRP A CE3  1 
ATOM   4361 C CZ2  . TRP A 1 279 ? 15.10687  4.64319   -16.89529 1.000 25.83799  ?  360 TRP A CZ2  1 
ATOM   4362 C CZ3  . TRP A 1 279 ? 13.53659  2.81572   -17.09938 1.000 22.43229  ?  360 TRP A CZ3  1 
ATOM   4363 C CH2  . TRP A 1 279 ? 14.03303  3.94217   -16.41685 1.000 21.54447  ?  360 TRP A CH2  1 
ATOM   4364 H H    A TRP A 1 279 ? 15.14499  4.42097   -21.99132 0.590 17.98734  ?  360 TRP A H    1 
ATOM   4365 D D    B TRP A 1 279 ? 15.14529  4.42159   -21.99200 0.410 17.98734  ?  360 TRP A D    1 
ATOM   4366 H HA   . TRP A 1 279 ? 14.97954  1.63032   -22.93424 1.000 18.74444  ?  360 TRP A HA   1 
ATOM   4367 H HB2  . TRP A 1 279 ? 15.57623  0.98805   -20.56926 1.000 17.71716  ?  360 TRP A HB2  1 
ATOM   4368 H HB3  . TRP A 1 279 ? 16.89934  1.76711   -21.48107 1.000 17.71716  ?  360 TRP A HB3  1 
ATOM   4369 H HD1  . TRP A 1 279 ? 17.72113  4.12558   -20.66374 1.000 25.28697  ?  360 TRP A HD1  1 
ATOM   4370 H HE3  . TRP A 1 279 ? 13.73190  1.49783   -18.78841 1.000 22.34755  ?  360 TRP A HE3  1 
ATOM   4371 H HZ2  . TRP A 1 279 ? 15.49266  5.50386   -16.36917 1.000 31.00559  ?  360 TRP A HZ2  1 
ATOM   4372 H HZ3  . TRP A 1 279 ? 12.68780  2.28483   -16.69428 1.000 26.91874  ?  360 TRP A HZ3  1 
ATOM   4373 H HH2  . TRP A 1 279 ? 13.55845  4.25881   -15.49983 1.000 25.85336  ?  360 TRP A HH2  1 
ATOM   4374 N N    . CYS A 1 280 ? 12.82171  3.38987   -21.35895 1.000 16.38428  ?  361 CYS A N    1 
ATOM   4375 C CA   . CYS A 1 280 ? 11.62450  3.41985   -20.51540 1.000 17.05661  ?  361 CYS A CA   1 
ATOM   4376 C C    . CYS A 1 280 ? 10.36267  3.34209   -21.35158 1.000 15.04422  ?  361 CYS A C    1 
ATOM   4377 O O    . CYS A 1 280 ? 10.06253  4.25052   -22.12992 1.000 16.77046  ?  361 CYS A O    1 
ATOM   4378 C CB   . CYS A 1 280 ? 11.61583  4.68560   -19.65832 1.000 16.53575  ?  361 CYS A CB   1 
ATOM   4379 S SG   . CYS A 1 280 ? 10.23311  4.61181   -18.49121 1.000 16.36489  ?  361 CYS A SG   1 
ATOM   4380 H H    A CYS A 1 280 ? 13.05816  4.28531   -21.78636 0.607 19.66114  ?  361 CYS A H    1 
ATOM   4381 D D    B CYS A 1 280 ? 13.05979  4.28445   -21.78727 0.393 19.66114  ?  361 CYS A D    1 
ATOM   4382 H HA   . CYS A 1 280 ? 11.64181  2.53314   -19.88174 1.000 20.46793  ?  361 CYS A HA   1 
ATOM   4383 H HB2  . CYS A 1 280 ? 12.54792  4.75829   -19.09794 1.000 19.84290  ?  361 CYS A HB2  1 
ATOM   4384 H HB3  . CYS A 1 280 ? 11.49444  5.56180   -20.29522 1.000 19.84290  ?  361 CYS A HB3  1 
ATOM   4385 N N    . ASN A 1 281 ? 9.62893   2.24852   -21.19123 1.000 12.81863  ?  362 ASN A N    1 
ATOM   4386 C CA   . ASN A 1 281 ? 8.31377   2.05214   -21.82794 1.000 12.12733  ?  362 ASN A CA   1 
ATOM   4387 C C    . ASN A 1 281 ? 8.33283   2.43060   -23.31208 1.000 15.54903  ?  362 ASN A C    1 
ATOM   4388 O O    . ASN A 1 281 ? 7.48137   3.16887   -23.79994 1.000 14.98627  ?  362 ASN A O    1 
ATOM   4389 C CB   . ASN A 1 281 ? 7.22736   2.86338   -21.12904 1.000 13.66406  ?  362 ASN A CB   1 
ATOM   4390 C CG   . ASN A 1 281 ? 7.16013   2.59006   -19.64632 1.000 14.07145  ?  362 ASN A CG   1 
ATOM   4391 O OD1  . ASN A 1 281 ? 7.14052   1.42607   -19.20587 1.000 14.91549  ?  362 ASN A OD1  1 
ATOM   4392 N ND2  . ASN A 1 281 ? 7.12652   3.64683   -18.86405 1.000 14.37835  ?  362 ASN A ND2  1 
ATOM   4393 H H    A ASN A 1 281 ? 9.91542   1.45689   -20.61534 0.944 15.38236  ?  362 ASN A H    1 
ATOM   4394 D D    B ASN A 1 281 ? 9.91649   1.45749   -20.61506 0.056 15.38236  ?  362 ASN A D    1 
ATOM   4395 H HA   . ASN A 1 281 ? 8.08600   0.98968   -21.74199 1.000 14.55280  ?  362 ASN A HA   1 
ATOM   4396 H HB2  . ASN A 1 281 ? 7.43182   3.92504   -21.26751 1.000 16.39688  ?  362 ASN A HB2  1 
ATOM   4397 H HB3  . ASN A 1 281 ? 6.26002   2.61032   -21.56299 1.000 16.39688  ?  362 ASN A HB3  1 
ATOM   4398 H HD21 A ASN A 1 281 ? 7.14625   4.58249   -19.26972 1.000 17.25402  ?  362 ASN A HD21 1 
ATOM   4399 D DD21 B ASN A 1 281 ? 7.14625   4.58249   -19.26972 0.000 17.25402  ?  362 ASN A DD21 1 
ATOM   4400 H HD22 A ASN A 1 281 ? 7.08073   3.53074   -17.85172 0.923 17.25402  ?  362 ASN A HD22 1 
ATOM   4401 D DD22 B ASN A 1 281 ? 7.08073   3.53074   -17.85172 0.077 17.25402  ?  362 ASN A DD22 1 
ATOM   4402 N N    . ILE A 1 282 ? 9.28719   1.87837   -24.07187 1.000 13.39067  ?  363 ILE A N    1 
ATOM   4403 C CA   . ILE A 1 282 ? 9.45838   2.31829   -25.44332 1.000 13.12293  ?  363 ILE A CA   1 
ATOM   4404 C C    . ILE A 1 282 ? 8.20367   2.01084   -26.23234 1.000 15.63786  ?  363 ILE A C    1 
ATOM   4405 O O    . ILE A 1 282 ? 7.69886   0.87805   -26.26041 1.000 14.30804  ?  363 ILE A O    1 
ATOM   4406 C CB   . ILE A 1 282 ? 10.70741  1.68046   -26.05981 1.000 14.85730  ?  363 ILE A CB   1 
ATOM   4407 C CG1  . ILE A 1 282 ? 11.98663  2.19815   -25.37865 1.000 14.69439  ?  363 ILE A CG1  1 
ATOM   4408 C CG2  . ILE A 1 282 ? 10.79102  2.00040   -27.55248 1.000 18.88973  ?  363 ILE A CG2  1 
ATOM   4409 C CD1  . ILE A 1 282 ? 12.16030  3.66566   -25.37296 1.000 17.40640  ?  363 ILE A CD1  1 
ATOM   4410 H H    A ILE A 1 282 ? 9.93192   1.14872   -23.76799 0.997 16.06881  ?  363 ILE A H    1 
ATOM   4411 D D    B ILE A 1 282 ? 9.93276   1.14873   -23.76978 0.003 16.06881  ?  363 ILE A D    1 
ATOM   4412 H HA   . ILE A 1 282 ? 9.60262   3.39862   -25.45726 1.000 15.74752  ?  363 ILE A HA   1 
ATOM   4413 H HB   . ILE A 1 282 ? 10.62604  0.60383   -25.91033 1.000 17.82876  ?  363 ILE A HB   1 
ATOM   4414 H HG12 . ILE A 1 282 ? 11.97771  1.86954   -24.33940 1.000 17.63327  ?  363 ILE A HG12 1 
ATOM   4415 H HG13 . ILE A 1 282 ? 12.84613  1.77281   -25.89677 1.000 17.63327  ?  363 ILE A HG13 1 
ATOM   4416 H HG21 . ILE A 1 282 ? 11.15739  3.01940   -27.67702 1.000 22.66767  ?  363 ILE A HG21 1 
ATOM   4417 H HG22 . ILE A 1 282 ? 11.47596  1.29842   -28.02806 1.000 22.66767  ?  363 ILE A HG22 1 
ATOM   4418 H HG23 . ILE A 1 282 ? 9.79792   1.90618   -27.99178 1.000 22.66767  ?  363 ILE A HG23 1 
ATOM   4419 H HD11 . ILE A 1 282 ? 13.20242  3.89883   -25.15450 1.000 20.88769  ?  363 ILE A HD11 1 
ATOM   4420 H HD12 . ILE A 1 282 ? 11.88890  4.05893   -26.35264 1.000 20.88769  ?  363 ILE A HD12 1 
ATOM   4421 H HD13 . ILE A 1 282 ? 11.51470  4.09644   -24.60763 1.000 20.88769  ?  363 ILE A HD13 1 
ATOM   4422 N N    . LYS A 1 283 ? 7.69223   3.04366   -26.90818 1.000 17.57327  ?  364 LYS A N    1 
ATOM   4423 C CA   . LYS A 1 283 ? 6.38996   2.97377   -27.56602 1.000 18.70887  ?  364 LYS A CA   1 
ATOM   4424 C C    . LYS A 1 283 ? 6.47833   2.10472   -28.80356 1.000 15.59294  ?  364 LYS A C    1 
ATOM   4425 O O    . LYS A 1 283 ? 7.41840   2.20389   -29.58892 1.000 18.75615  ?  364 LYS A O    1 
ATOM   4426 C CB   . LYS A 1 283 ? 5.99472   4.40042   -27.95102 1.000 22.25869  ?  364 LYS A CB   1 
ATOM   4427 C CG   . LYS A 1 283 ? 4.58489   4.53760   -28.48841 1.000 41.09404  ?  364 LYS A CG   1 
ATOM   4428 C CD   . LYS A 1 283 ? 4.08522   5.97978   -28.39256 1.000 44.78286  ?  364 LYS A CD   1 
ATOM   4429 C CE   . LYS A 1 283 ? 4.95035   6.92781   -29.21815 1.000 60.79846  ?  364 LYS A CE   1 
ATOM   4430 N NZ   . LYS A 1 283 ? 4.47161   8.33409   -29.10760 1.000 70.39150  ?  364 LYS A NZ   1 
ATOM   4431 H H    A LYS A 1 283 ? 8.15799   3.94447   -27.01776 0.863 21.08792  ?  364 LYS A H    1 
ATOM   4432 D D    B LYS A 1 283 ? 8.15676   3.94501   -27.01862 0.137 21.08792  ?  364 LYS A D    1 
ATOM   4433 H HA   . LYS A 1 283 ? 5.63296   2.54090   -26.91205 1.000 22.45064  ?  364 LYS A HA   1 
ATOM   4434 H HB2  . LYS A 1 283 ? 6.07321   5.03308   -27.06690 1.000 26.71043  ?  364 LYS A HB2  1 
ATOM   4435 H HB3  . LYS A 1 283 ? 6.67757   4.75338   -28.72383 1.000 26.71043  ?  364 LYS A HB3  1 
ATOM   4436 H HG2  . LYS A 1 283 ? 4.56740   4.23815   -29.53632 1.000 49.31285  ?  364 LYS A HG2  1 
ATOM   4437 H HG3  . LYS A 1 283 ? 3.91429   3.90367   -27.90829 1.000 49.31285  ?  364 LYS A HG3  1 
ATOM   4438 H HD2  . LYS A 1 283 ? 3.06347   6.03356   -28.76839 1.000 53.73943  ?  364 LYS A HD2  1 
ATOM   4439 H HD3  . LYS A 1 283 ? 4.11749   6.30465   -27.35260 1.000 53.73943  ?  364 LYS A HD3  1 
ATOM   4440 H HE2  . LYS A 1 283 ? 5.97818   6.88557   -28.85776 1.000 72.95815  ?  364 LYS A HE2  1 
ATOM   4441 H HE3  . LYS A 1 283 ? 4.91054   6.63286   -30.26673 1.000 72.95815  ?  364 LYS A HE3  1 
ATOM   4442 N N    . GLY A 1 284 ? 5.48739   1.23533   -28.97617 1.000 16.84723  ?  365 GLY A N    1 
ATOM   4443 C CA   . GLY A 1 284 ? 5.42881   0.39745   -30.13668 1.000 15.74703  ?  365 GLY A CA   1 
ATOM   4444 C C    . GLY A 1 284 ? 6.08956   -0.95742  -29.99296 1.000 17.60069  ?  365 GLY A C    1 
ATOM   4445 O O    . GLY A 1 284 ? 6.06168   -1.74179  -30.94567 1.000 19.09823  ?  365 GLY A O    1 
ATOM   4446 H H    A GLY A 1 284 ? 4.71772   1.09990   -28.32069 0.541 20.21667  ?  365 GLY A H    1 
ATOM   4447 D D    B GLY A 1 284 ? 4.71797   1.10035   -28.32031 0.459 20.21667  ?  365 GLY A D    1 
ATOM   4448 H HA2  . GLY A 1 284 ? 4.38216   0.22889   -30.39005 1.000 18.89644  ?  365 GLY A HA2  1 
ATOM   4449 H HA3  . GLY A 1 284 ? 5.91501   0.91562   -30.96325 1.000 18.89644  ?  365 GLY A HA3  1 
ATOM   4450 N N    . ALA A 1 285 ? 6.66042   -1.25884  -28.82959 1.000 16.95706  ?  366 ALA A N    1 
ATOM   4451 C CA   . ALA A 1 285 ? 7.29654   -2.54801  -28.63349 1.000 14.28618  ?  366 ALA A CA   1 
ATOM   4452 C C    . ALA A 1 285 ? 6.30015   -3.67700  -28.75013 1.000 13.55034  ?  366 ALA A C    1 
ATOM   4453 O O    . ALA A 1 285 ? 5.12044   -3.53661  -28.42583 1.000 14.81233  ?  366 ALA A O    1 
ATOM   4454 C CB   . ALA A 1 285 ? 7.90677   -2.60610  -27.25103 1.000 14.92601  ?  366 ALA A CB   1 
ATOM   4455 H H    A ALA A 1 285 ? 6.69635   -0.63964  -28.01984 0.612 20.34847  ?  366 ALA A H    1 
ATOM   4456 D D    B ALA A 1 285 ? 6.69724   -0.64088  -28.01893 0.388 20.34847  ?  366 ALA A D    1 
ATOM   4457 H HA   . ALA A 1 285 ? 8.06604   -2.67670  -29.39467 1.000 17.14342  ?  366 ALA A HA   1 
ATOM   4458 H HB1  . ALA A 1 285 ? 8.70457   -3.34879  -27.24621 1.000 17.91121  ?  366 ALA A HB1  1 
ATOM   4459 H HB2  . ALA A 1 285 ? 8.31048   -1.62528  -26.99983 1.000 17.91121  ?  366 ALA A HB2  1 
ATOM   4460 H HB3  . ALA A 1 285 ? 7.13484   -2.88513  -26.53383 1.000 17.91121  ?  366 ALA A HB3  1 
ATOM   4461 N N    . GLY A 1 286 ? 6.79281   -4.81099  -29.25401 1.000 14.67194  ?  367 GLY A N    1 
ATOM   4462 C CA   . GLY A 1 286 ? 5.99866   -6.01598  -29.34782 1.000 13.01651  ?  367 GLY A CA   1 
ATOM   4463 C C    . GLY A 1 286 ? 6.70565   -7.17717  -28.68076 1.000 12.44739  ?  367 GLY A C    1 
ATOM   4464 O O    . GLY A 1 286 ? 7.91443   -7.20445  -28.56871 1.000 14.10880  ?  367 GLY A O    1 
ATOM   4465 H H    A GLY A 1 286 ? 7.74480   -4.91669  -29.60466 1.000 17.60633  ?  367 GLY A H    1 
ATOM   4466 D D    B GLY A 1 286 ? 7.74476   -4.91690  -29.60471 0.000 17.60633  ?  367 GLY A D    1 
ATOM   4467 H HA2  . GLY A 1 286 ? 5.03702   -5.86247  -28.85816 1.000 15.61982  ?  367 GLY A HA2  1 
ATOM   4468 H HA3  . GLY A 1 286 ? 5.82789   -6.26403  -30.39539 1.000 15.61982  ?  367 GLY A HA3  1 
ATOM   4469 N N    . PHE A 1 287 ? 5.91341   -8.16316  -28.28387 1.000 14.13545  ?  368 PHE A N    1 
ATOM   4470 C CA   . PHE A 1 287 ? 6.47357   -9.38893  -27.75609 1.000 13.26867  ?  368 PHE A CA   1 
ATOM   4471 C C    . PHE A 1 287 ? 7.35106   -10.00166 -28.83639 1.000 14.52172  ?  368 PHE A C    1 
ATOM   4472 O O    . PHE A 1 287 ? 6.99173   -10.02752 -30.01101 1.000 15.43530  ?  368 PHE A O    1 
ATOM   4473 C CB   . PHE A 1 287 ? 5.35747   -10.37252 -27.36949 1.000 13.49699  ?  368 PHE A CB   1 
ATOM   4474 C CG   . PHE A 1 287 ? 4.70824   -10.07747 -26.06193 1.000 13.88842  ?  368 PHE A CG   1 
ATOM   4475 C CD1  . PHE A 1 287 ? 5.43471   -9.91562  -24.90395 1.000 15.65001  ?  368 PHE A CD1  1 
ATOM   4476 C CD2  . PHE A 1 287 ? 3.32687   -9.99011  -25.97690 1.000 15.07082  ?  368 PHE A CD2  1 
ATOM   4477 C CE1  . PHE A 1 287 ? 4.81751   -9.65629  -23.69654 1.000 16.43600  ?  368 PHE A CE1  1 
ATOM   4478 C CE2  . PHE A 1 287 ? 2.72058   -9.72312  -24.76767 1.000 17.41060  ?  368 PHE A CE2  1 
ATOM   4479 C CZ   . PHE A 1 287 ? 3.45130   -9.57059  -23.63316 1.000 18.38971  ?  368 PHE A CZ   1 
ATOM   4480 H H    A PHE A 1 287 ? 4.89415   -8.14112  -28.31583 1.000 16.96254  ?  368 PHE A H    1 
ATOM   4481 D D    B PHE A 1 287 ? 4.89410   -8.14283  -28.31511 0.000 16.96254  ?  368 PHE A D    1 
ATOM   4482 H HA   . PHE A 1 287 ? 7.05656   -9.19192  -26.85642 1.000 15.92240  ?  368 PHE A HA   1 
ATOM   4483 H HB2  . PHE A 1 287 ? 4.58407   -10.34095 -28.13692 1.000 16.19639  ?  368 PHE A HB2  1 
ATOM   4484 H HB3  . PHE A 1 287 ? 5.78188   -11.37468 -27.30893 1.000 16.19639  ?  368 PHE A HB3  1 
ATOM   4485 H HD1  . PHE A 1 287 ? 6.51129   -9.99321  -24.94078 1.000 18.78002  ?  368 PHE A HD1  1 
ATOM   4486 H HD2  . PHE A 1 287 ? 2.72354   -10.13176 -26.86139 1.000 18.08498  ?  368 PHE A HD2  1 
ATOM   4487 H HE1  . PHE A 1 287 ? 5.41018   -9.52125  -22.80384 1.000 19.72319  ?  368 PHE A HE1  1 
ATOM   4488 H HE2  . PHE A 1 287 ? 1.64526   -9.63369  -24.72189 1.000 20.89271  ?  368 PHE A HE2  1 
ATOM   4489 H HZ   . PHE A 1 287 ? 2.96019   -9.38346  -22.68966 1.000 22.06765  ?  368 PHE A HZ   1 
ATOM   4490 N N    . GLY A 1 288 ? 8.53255   -10.48460 -28.43592 1.000 13.23193  ?  369 GLY A N    1 
ATOM   4491 C CA   . GLY A 1 288 ? 9.48156   -11.07516 -29.33737 1.000 12.99214  ?  369 GLY A CA   1 
ATOM   4492 C C    . GLY A 1 288 ? 9.42971   -12.58857 -29.30658 1.000 13.02962  ?  369 GLY A C    1 
ATOM   4493 O O    . GLY A 1 288 ? 8.46144   -13.21632 -28.85828 1.000 14.06535  ?  369 GLY A O    1 
ATOM   4494 H H    A GLY A 1 288 ? 8.84978   -10.47149 -27.46660 0.907 15.87831  ?  369 GLY A H    1 
ATOM   4495 D D    B GLY A 1 288 ? 8.84798   -10.47056 -27.46602 0.093 15.87831  ?  369 GLY A D    1 
ATOM   4496 H HA2  . GLY A 1 288 ? 9.27051   -10.74324 -30.35392 1.000 15.59057  ?  369 GLY A HA2  1 
ATOM   4497 H HA3  . GLY A 1 288 ? 10.48770  -10.75866 -29.06240 1.000 15.59057  ?  369 GLY A HA3  1 
ATOM   4498 N N    . THR A 1 289 ? 10.52639  -13.18738 -29.75682 1.000 13.34966  ?  370 THR A N    1 
ATOM   4499 C CA   . THR A 1 289 ? 10.64665  -14.63300 -29.86603 1.000 13.81318  ?  370 THR A CA   1 
ATOM   4500 C C    . THR A 1 289 ? 10.36170  -15.27783 -28.52219 1.000 13.70209  ?  370 THR A C    1 
ATOM   4501 O O    . THR A 1 289 ? 10.89367  -14.85368 -27.49337 1.000 13.32579  ?  370 THR A O    1 
ATOM   4502 C CB   . THR A 1 289 ? 12.06983  -14.94552 -30.29307 1.000 14.67928  ?  370 THR A CB   1 
ATOM   4503 O OG1  . THR A 1 289 ? 12.30137  -14.38084 -31.60112 1.000 18.03543  ?  370 THR A OG1  1 
ATOM   4504 C CG2  . THR A 1 289 ? 12.34641  -16.42854 -30.32573 1.000 17.61876  ?  370 THR A CG2  1 
ATOM   4505 H H    A THR A 1 289 ? 11.36372  -12.68953 -30.05917 0.604 16.01960  ?  370 THR A H    1 
ATOM   4506 D D    B THR A 1 289 ? 11.36428  -12.69063 -30.05943 0.396 16.01960  ?  370 THR A D    1 
ATOM   4507 H HA   . THR A 1 289 ? 9.94286   -15.03162 -30.59670 1.000 16.57582  ?  370 THR A HA   1 
ATOM   4508 H HB   . THR A 1 289 ? 12.75758  -14.51378 -29.56595 1.000 17.61514  ?  370 THR A HB   1 
ATOM   4509 H HG21 . THR A 1 289 ? 11.43167  -16.98307 -30.11633 1.000 21.14251  ?  370 THR A HG21 1 
ATOM   4510 H HG22 . THR A 1 289 ? 12.71766  -16.71697 -31.30913 1.000 21.14251  ?  370 THR A HG22 1 
ATOM   4511 H HG23 . THR A 1 289 ? 13.09490  -16.68478 -29.57593 1.000 21.14251  ?  370 THR A HG23 1 
ATOM   4512 N N    . ARG A 1 290 ? 9.54662   -16.31568 -28.52915 1.000 13.01581  ?  371 ARG A N    1 
ATOM   4513 C CA   . ARG A 1 290 ? 9.17922   -16.98343 -27.30635 1.000 14.82608  ?  371 ARG A CA   1 
ATOM   4514 C C    . ARG A 1 290 ? 10.35719  -17.79414 -26.74896 1.000 12.83832  ?  371 ARG A C    1 
ATOM   4515 O O    . ARG A 1 290 ? 11.28081  -18.20396 -27.48055 1.000 13.76594  ?  371 ARG A O    1 
ATOM   4516 C CB   . ARG A 1 290 ? 7.98061   -17.91317 -27.53747 1.000 17.48354  ?  371 ARG A CB   1 
ATOM   4517 C CG   . ARG A 1 290 ? 6.62852   -17.25935 -27.22130 1.000 28.32308  ?  371 ARG A CG   1 
ATOM   4518 C CD   . ARG A 1 290 ? 6.49858   -15.93195 -27.90254 1.000 24.95780  ?  371 ARG A CD   1 
ATOM   4519 N NE   . ARG A 1 290 ? 5.70927   -16.10481 -29.08840 1.000 34.80047  ?  371 ARG A NE   1 
ATOM   4520 C CZ   . ARG A 1 290 ? 5.41824   -15.15887 -29.97330 1.000 29.38248  ?  371 ARG A CZ   1 
ATOM   4521 N NH1  . ARG A 1 290 ? 6.01713   -13.97731 -29.97529 1.000 22.83303  ?  371 ARG A NH1  1 
ATOM   4522 N NH2  . ARG A 1 290 ? 4.47878   -15.40469 -30.87007 1.000 34.99239  ?  371 ARG A NH2  1 
ATOM   4523 H H    A ARG A 1 290 ? 9.12532   -16.71602 -29.36738 0.670 15.61897  ?  371 ARG A H    1 
ATOM   4524 D D    B ARG A 1 290 ? 9.12442   -16.71734 -29.36630 0.330 15.61897  ?  371 ARG A D    1 
ATOM   4525 H HA   . ARG A 1 290 ? 8.89979   -16.23530 -26.56451 1.000 17.79130  ?  371 ARG A HA   1 
ATOM   4526 H HB2  . ARG A 1 290 ? 7.96808   -18.21676 -28.58427 1.000 20.98025  ?  371 ARG A HB2  1 
ATOM   4527 H HB3  . ARG A 1 290 ? 8.08620   -18.78857 -26.89667 1.000 20.98025  ?  371 ARG A HB3  1 
ATOM   4528 H HG2  . ARG A 1 290 ? 5.82286   -17.90557 -27.56972 1.000 33.98770  ?  371 ARG A HG2  1 
ATOM   4529 H HG3  . ARG A 1 290 ? 6.54334   -17.10423 -26.14576 1.000 33.98770  ?  371 ARG A HG3  1 
ATOM   4530 H HD2  . ARG A 1 290 ? 6.00120   -15.22063 -27.24320 1.000 29.94936  ?  371 ARG A HD2  1 
ATOM   4531 H HD3  . ARG A 1 290 ? 7.48340   -15.55670 -28.18077 1.000 29.94936  ?  371 ARG A HD3  1 
ATOM   4532 H HE   . ARG A 1 290 ? 5.33862   -17.03805 -29.26750 0.000 41.76056  ?  371 ARG A HE   1 
ATOM   4533 N N    . PRO A 1 291 ? 10.37305  -18.00075 -25.44435 1.000 10.60869  ?  372 PRO A N    1 
ATOM   4534 C CA   . PRO A 1 291 ? 11.48758  -18.73672 -24.83772 1.000 11.52563  ?  372 PRO A CA   1 
ATOM   4535 C C    . PRO A 1 291 ? 11.71212  -20.08773 -25.48066 1.000 12.96932  ?  372 PRO A C    1 
ATOM   4536 O O    . PRO A 1 291 ? 10.76509  -20.82070 -25.78883 1.000 13.74685  ?  372 PRO A O    1 
ATOM   4537 C CB   . PRO A 1 291 ? 11.05506  -18.88197 -23.36696 1.000 13.79127  ?  372 PRO A CB   1 
ATOM   4538 C CG   . PRO A 1 291 ? 10.20112  -17.64253 -23.14609 1.000 13.78878  ?  372 PRO A CG   1 
ATOM   4539 C CD   . PRO A 1 291 ? 9.41682   -17.50073 -24.43766 1.000 11.29017  ?  372 PRO A CD   1 
ATOM   4540 H HA   . PRO A 1 291 ? 12.40283  -18.14940 -24.91177 1.000 13.83075  ?  372 PRO A HA   1 
ATOM   4541 H HB2  . PRO A 1 291 ? 10.47690  -19.79546 -23.22779 1.000 16.54952  ?  372 PRO A HB2  1 
ATOM   4542 H HB3  . PRO A 1 291 ? 11.92631  -18.88878 -22.71200 1.000 16.54952  ?  372 PRO A HB3  1 
ATOM   4543 H HG2  . PRO A 1 291 ? 9.53548   -17.79133 -22.29586 1.000 16.54654  ?  372 PRO A HG2  1 
ATOM   4544 H HG3  . PRO A 1 291 ? 10.83677  -16.77387 -22.97436 1.000 16.54654  ?  372 PRO A HG3  1 
ATOM   4545 H HD2  . PRO A 1 291 ? 8.51421   -18.11144 -24.41714 1.000 13.54820  ?  372 PRO A HD2  1 
ATOM   4546 H HD3  . PRO A 1 291 ? 9.15785   -16.45893 -24.62656 1.000 13.54820  ?  372 PRO A HD3  1 
ATOM   4547 N N    . THR A 1 292 ? 12.98096  -20.43125 -25.69941 1.000 12.27620  ?  373 THR A N    1 
ATOM   4548 C CA   . THR A 1 292 ? 13.35188  -21.67694 -26.34744 1.000 13.06756  ?  373 THR A CA   1 
ATOM   4549 C C    . THR A 1 292 ? 14.84005  -21.92243 -26.15758 1.000 11.71127  ?  373 THR A C    1 
ATOM   4550 O O    . THR A 1 292 ? 15.63818  -21.00105 -26.13120 1.000 12.53423  ?  373 THR A O    1 
ATOM   4551 C CB   . THR A 1 292 ? 13.02227  -21.61989 -27.84889 1.000 14.16559  ?  373 THR A CB   1 
ATOM   4552 O OG1  . THR A 1 292 ? 13.38667  -22.90262 -28.42966 1.000 16.16812  ?  373 THR A OG1  1 
ATOM   4553 C CG2  . THR A 1 292 ? 13.76053  -20.50966 -28.57786 1.000 13.14824  ?  373 THR A CG2  1 
ATOM   4554 H H    A THR A 1 292 ? 13.78075  -19.85663 -25.43381 0.624 14.73144  ?  373 THR A H    1 
ATOM   4555 D D    B THR A 1 292 ? 13.78055  -19.85641 -25.43369 0.376 14.73144  ?  373 THR A D    1 
ATOM   4556 H HA   . THR A 1 292 ? 12.81314  -22.50333 -25.88382 1.000 15.68107  ?  373 THR A HA   1 
ATOM   4557 H HB   . THR A 1 292 ? 11.96032  -21.40831 -27.97374 1.000 16.99871  ?  373 THR A HB   1 
ATOM   4558 H HG21 . THR A 1 292 ? 13.45769  -19.53945 -28.18404 1.000 15.77789  ?  373 THR A HG21 1 
ATOM   4559 H HG22 . THR A 1 292 ? 14.83590  -20.62607 -28.44319 1.000 15.77789  ?  373 THR A HG22 1 
ATOM   4560 H HG23 . THR A 1 292 ? 13.53138  -20.54631 -29.64286 1.000 15.77789  ?  373 THR A HG23 1 
ATOM   4561 N N    . THR A 1 293 ? 15.20160  -23.19376 -26.10070 1.000 12.86481  ?  374 THR A N    1 
ATOM   4562 C CA   . THR A 1 293 ? 16.58475  -23.61535 -26.12866 1.000 11.95595  ?  374 THR A CA   1 
ATOM   4563 C C    . THR A 1 293 ? 17.09526  -23.83978 -27.54298 1.000 15.03200  ?  374 THR A C    1 
ATOM   4564 O O    . THR A 1 293 ? 18.26139  -24.17821 -27.71197 1.000 15.82130  ?  374 THR A O    1 
ATOM   4565 C CB   . THR A 1 293 ? 16.79540  -24.86246 -25.28486 1.000 14.52598  ?  374 THR A CB   1 
ATOM   4566 O OG1  . THR A 1 293 ? 15.94369  -25.89683 -25.78623 1.000 20.23021  ?  374 THR A OG1  1 
ATOM   4567 C CG2  . THR A 1 293 ? 16.48974  -24.62992 -23.82097 1.000 13.52631  ?  374 THR A CG2  1 
ATOM   4568 H H    A THR A 1 293 ? 14.54225  -23.96908 -26.03340 0.677 15.43778  ?  374 THR A H    1 
ATOM   4569 D D    B THR A 1 293 ? 14.54128  -23.96826 -26.03341 0.323 15.43778  ?  374 THR A D    1 
ATOM   4570 H HA   . THR A 1 293 ? 17.19248  -22.83274 -25.67447 1.000 14.34714  ?  374 THR A HA   1 
ATOM   4571 H HB   . THR A 1 293 ? 17.84346  -25.15615 -25.34339 1.000 17.43118  ?  374 THR A HB   1 
ATOM   4572 H HG21 . THR A 1 293 ? 15.50113  -24.18376 -23.71285 1.000 16.23158  ?  374 THR A HG21 1 
ATOM   4573 H HG22 . THR A 1 293 ? 16.51176  -25.57630 -23.28062 1.000 16.23158  ?  374 THR A HG22 1 
ATOM   4574 H HG23 . THR A 1 293 ? 17.23045  -23.95785 -23.38764 1.000 16.23158  ?  374 THR A HG23 1 
ATOM   4575 N N    A ASN A 1 294 ? 16.24780  -23.68317 -28.55725 0.583 15.02385  ?  375 ASN A N    1 
ATOM   4576 N N    B ASN A 1 294 ? 16.27209  -23.64750 -28.56314 0.417 15.19619  ?  375 ASN A N    1 
ATOM   4577 C CA   A ASN A 1 294 ? 16.67182  -23.71493 -29.96035 0.583 15.55884  ?  375 ASN A CA   1 
ATOM   4578 C CA   B ASN A 1 294 ? 16.73774  -23.76619 -29.94698 0.417 15.44249  ?  375 ASN A CA   1 
ATOM   4579 C C    A ASN A 1 294 ? 17.11722  -22.30044 -30.30368 0.583 16.27756  ?  375 ASN A C    1 
ATOM   4580 C C    B ASN A 1 294 ? 17.16098  -22.37691 -30.41753 0.417 16.01232  ?  375 ASN A C    1 
ATOM   4581 O O    A ASN A 1 294 ? 16.33507  -21.46584 -30.76729 0.583 21.28343  ?  375 ASN A O    1 
ATOM   4582 O O    B ASN A 1 294 ? 16.42916  -21.65757 -31.09340 0.417 18.43770  ?  375 ASN A O    1 
ATOM   4583 C CB   A ASN A 1 294 ? 15.52469  -24.17920 -30.85095 0.583 20.48368  ?  375 ASN A CB   1 
ATOM   4584 C CB   B ASN A 1 294 ? 15.65107  -24.41060 -30.79884 0.417 21.03726  ?  375 ASN A CB   1 
ATOM   4585 C CG   A ASN A 1 294 ? 15.92344  -24.28948 -32.32329 0.583 28.23294  ?  375 ASN A CG   1 
ATOM   4586 C CG   B ASN A 1 294 ? 15.33597  -25.82663 -30.34201 0.417 27.22462  ?  375 ASN A CG   1 
ATOM   4587 O OD1  A ASN A 1 294 ? 17.09495  -24.20538 -32.67731 0.583 31.97789  ?  375 ASN A OD1  1 
ATOM   4588 O OD1  B ASN A 1 294 ? 16.24139  -26.57882 -29.96514 0.417 27.29667  ?  375 ASN A OD1  1 
ATOM   4589 N ND2  A ASN A 1 294 ? 14.93317  -24.48688 -33.18581 0.583 37.25426  ?  375 ASN A ND2  1 
ATOM   4590 N ND2  B ASN A 1 294 ? 14.05044  -26.19127 -30.35244 0.417 26.80170  ?  375 ASN A ND2  1 
ATOM   4591 H H    A ASN A 1 294 ? 15.24610  -23.53012 -28.44076 0.489 18.02862  ?  375 ASN A H    1 
ATOM   4592 D D    B ASN A 1 294 ? 15.28448  -23.41016 -28.46989 0.511 18.23542  ?  375 ASN A D    1 
ATOM   4593 H HA   A ASN A 1 294 ? 17.50523  -24.40396 -30.09734 0.583 18.67061  ?  375 ASN A HA   1 
ATOM   4594 H HA   B ASN A 1 294 ? 17.61849  -24.40497 -30.01285 0.417 18.53099  ?  375 ASN A HA   1 
ATOM   4595 H HB2  A ASN A 1 294 ? 15.19219  -25.16229 -30.51768 0.583 24.58041  ?  375 ASN A HB2  1 
ATOM   4596 H HB2  B ASN A 1 294 ? 14.73923  -23.81790 -30.72569 0.417 25.24471  ?  375 ASN A HB2  1 
ATOM   4597 H HB3  A ASN A 1 294 ? 14.70578  -23.46369 -30.77664 0.583 24.58041  ?  375 ASN A HB3  1 
ATOM   4598 H HB3  B ASN A 1 294 ? 15.98583  -24.45327 -31.83528 0.417 25.24471  ?  375 ASN A HB3  1 
ATOM   4599 N N    . THR A 1 295 ? 18.38253  -22.00658 -30.03603 1.000 14.57289  ?  376 THR A N    1 
ATOM   4600 C CA   . THR A 1 295 ? 18.87205  -20.64421 -30.11265 1.000 15.59131  ?  376 THR A CA   1 
ATOM   4601 C C    . THR A 1 295 ? 19.73328  -20.37620 -31.33199 1.000 17.41295  ?  376 THR A C    1 
ATOM   4602 O O    . THR A 1 295 ? 19.99994  -19.21413 -31.61434 1.000 19.82580  ?  376 THR A O    1 
ATOM   4603 C CB   . THR A 1 295 ? 19.74050  -20.34888 -28.86737 1.000 14.50520  ?  376 THR A CB   1 
ATOM   4604 O OG1  . THR A 1 295 ? 20.88463  -21.21222 -28.93441 1.000 15.11634  ?  376 THR A OG1  1 
ATOM   4605 C CG2  . THR A 1 295 ? 18.96530  -20.61329 -27.59847 1.000 15.08022  ?  376 THR A CG2  1 
ATOM   4606 H H    A THR A 1 295 ? 19.08823  -22.69111 -29.76435 0.572 17.48747  ?  376 THR A H    1 
ATOM   4607 D D    B THR A 1 295 ? 19.07394  -22.65426 -29.65804 0.428 17.48747  ?  376 THR A D    1 
ATOM   4608 H HA   . THR A 1 295 ? 18.01754  -19.96805 -30.13949 1.000 18.70957  ?  376 THR A HA   1 
ATOM   4609 H HB   . THR A 1 295 ? 20.04759  -19.30337 -28.84079 1.000 17.40624  ?  376 THR A HB   1 
ATOM   4610 H HG21 . THR A 1 295 ? 18.66829  -21.66112 -27.55455 1.000 18.09626  ?  376 THR A HG21 1 
ATOM   4611 H HG22 . THR A 1 295 ? 19.58254  -20.38386 -26.72987 1.000 18.09626  ?  376 THR A HG22 1 
ATOM   4612 H HG23 . THR A 1 295 ? 18.07103  -19.99069 -27.57135 1.000 18.09626  ?  376 THR A HG23 1 
ATOM   4613 N N    . GLY A 1 296 ? 20.21013  -21.42390 -31.99493 1.000 19.23916  ?  377 GLY A N    1 
ATOM   4614 C CA   . GLY A 1 296 ? 21.08651  -21.26276 -33.12631 1.000 20.35212  ?  377 GLY A CA   1 
ATOM   4615 C C    . GLY A 1 296 ? 22.48515  -20.84340 -32.81220 1.000 18.01469  ?  377 GLY A C    1 
ATOM   4616 O O    . GLY A 1 296 ? 23.27315  -20.58775 -33.73934 1.000 20.29232  ?  377 GLY A O    1 
ATOM   4617 H H    A GLY A 1 296 ? 20.00186  -22.39558 -31.76499 0.699 23.08699  ?  377 GLY A H    1 
ATOM   4618 D D    B GLY A 1 296 ? 20.00243  -22.39587 -31.76573 0.301 23.08699  ?  377 GLY A D    1 
ATOM   4619 H HA2  . GLY A 1 296 ? 21.14091  -22.21272 -33.65802 1.000 24.42254  ?  377 GLY A HA2  1 
ATOM   4620 H HA3  . GLY A 1 296 ? 20.65949  -20.50947 -33.78835 1.000 24.42254  ?  377 GLY A HA3  1 
ATOM   4621 N N    . SER A 1 297 ? 22.86336  -20.80456 -31.54912 1.000 14.09185  ?  378 SER A N    1 
ATOM   4622 C CA   . SER A 1 297 ? 24.20980  -20.40027 -31.16142 1.000 15.04634  ?  378 SER A CA   1 
ATOM   4623 C C    . SER A 1 297 ? 24.78402  -21.33123 -30.12760 1.000 17.44092  ?  378 SER A C    1 
ATOM   4624 O O    . SER A 1 297 ? 24.09146  -21.71795 -29.19285 1.000 16.43493  ?  378 SER A O    1 
ATOM   4625 C CB   . SER A 1 297 ? 24.22089  -18.98274 -30.55569 1.000 17.64149  ?  378 SER A CB   1 
ATOM   4626 O OG   . SER A 1 297 ? 25.51583  -18.67968 -30.02218 1.000 19.90989  ?  378 SER A OG   1 
ATOM   4627 H H    A SER A 1 297 ? 22.26030  -21.04776 -30.76327 0.709 16.91022  ?  378 SER A H    1 
ATOM   4628 D D    B SER A 1 297 ? 22.25889  -21.04813 -30.76447 0.291 16.91022  ?  378 SER A D    1 
ATOM   4629 H HA   . SER A 1 297 ? 24.83083  -20.43895 -32.05636 1.000 18.05561  ?  378 SER A HA   1 
ATOM   4630 H HB2  . SER A 1 297 ? 23.97718  -18.25977 -31.33415 1.000 21.16978  ?  378 SER A HB2  1 
ATOM   4631 H HB3  . SER A 1 297 ? 23.48349  -18.93085 -29.75465 1.000 21.16978  ?  378 SER A HB3  1 
ATOM   4632 N N    A GLN A 1 298 ? 26.05925  -21.69581 -30.31781 0.497 15.67292  ?  379 GLN A N    1 
ATOM   4633 N N    B GLN A 1 298 ? 26.07032  -21.67609 -30.30925 0.503 15.69677  ?  379 GLN A N    1 
ATOM   4634 C CA   A GLN A 1 298 ? 26.74823  -22.52380 -29.34356 0.497 16.58656  ?  379 GLN A CA   1 
ATOM   4635 C CA   B GLN A 1 298 ? 26.78137  -22.52295 -29.36309 0.503 16.63023  ?  379 GLN A CA   1 
ATOM   4636 C C    A GLN A 1 298 ? 26.74547  -21.88750 -27.95961 0.497 16.35358  ?  379 GLN A C    1 
ATOM   4637 C C    B GLN A 1 298 ? 26.90815  -21.87967 -27.98719 0.503 16.22666  ?  379 GLN A C    1 
ATOM   4638 O O    A GLN A 1 298 ? 26.72345  -22.58833 -26.94084 0.497 17.90562  ?  379 GLN A O    1 
ATOM   4639 O O    B GLN A 1 298 ? 27.14660  -22.57713 -26.99818 0.503 19.87259  ?  379 GLN A O    1 
ATOM   4640 C CB   A GLN A 1 298 ? 28.18899  -22.72570 -29.82186 0.497 19.96742  ?  379 GLN A CB   1 
ATOM   4641 C CB   B GLN A 1 298 ? 28.17882  -22.85346 -29.91916 0.503 20.10914  ?  379 GLN A CB   1 
ATOM   4642 C CG   A GLN A 1 298 ? 29.06042  -23.52860 -28.89093 0.497 23.83450  ?  379 GLN A CG   1 
ATOM   4643 C CG   B GLN A 1 298 ? 29.10415  -21.65090 -30.14503 0.503 18.07682  ?  379 GLN A CG   1 
ATOM   4644 C CD   A GLN A 1 298 ? 30.39166  -23.90017 -29.53386 0.497 33.63532  ?  379 GLN A CD   1 
ATOM   4645 C CD   B GLN A 1 298 ? 30.17302  -21.90470 -31.20619 0.503 29.02044  ?  379 GLN A CD   1 
ATOM   4646 O OE1  A GLN A 1 298 ? 31.06348  -23.05084 -30.12497 0.497 28.57567  ?  379 GLN A OE1  1 
ATOM   4647 O OE1  B GLN A 1 298 ? 30.72627  -20.97131 -31.79396 0.503 29.14330  ?  379 GLN A OE1  1 
ATOM   4648 N NE2  A GLN A 1 298 ? 30.76606  -25.18178 -29.43925 0.497 22.20474  ?  379 GLN A NE2  1 
ATOM   4649 N NE2  B GLN A 1 298 ? 30.45521  -23.17894 -31.46313 0.503 34.08714  ?  379 GLN A NE2  1 
ATOM   4650 H H    A GLN A 1 298 ? 26.62560  -21.43437 -31.12484 0.770 18.80751  ?  379 GLN A H    1 
ATOM   4651 D D    B GLN A 1 298 ? 26.63996  -21.38184 -31.10255 0.230 18.83612  ?  379 GLN A D    1 
ATOM   4652 H HA   A GLN A 1 298 ? 26.24946  -23.48956 -29.26211 0.497 19.90388  ?  379 GLN A HA   1 
ATOM   4653 H HA   B GLN A 1 298 ? 26.22933  -23.45468 -29.23970 0.503 19.95627  ?  379 GLN A HA   1 
ATOM   4654 H HB2  A GLN A 1 298 ? 28.16526  -23.24698 -30.77884 0.497 23.96091  ?  379 GLN A HB2  1 
ATOM   4655 H HB2  B GLN A 1 298 ? 28.67863  -23.51895 -29.21531 0.503 24.13097  ?  379 GLN A HB2  1 
ATOM   4656 H HB3  A GLN A 1 298 ? 28.65332  -21.74688 -29.94192 0.497 23.96091  ?  379 GLN A HB3  1 
ATOM   4657 H HB3  B GLN A 1 298 ? 28.05547  -23.35221 -30.88047 0.503 24.13097  ?  379 GLN A HB3  1 
ATOM   4658 H HG2  A GLN A 1 298 ? 29.26637  -22.94080 -27.99640 0.497 28.60140  ?  379 GLN A HG2  1 
ATOM   4659 H HG2  B GLN A 1 298 ? 28.50500  -20.80030 -30.46998 0.503 21.69219  ?  379 GLN A HG2  1 
ATOM   4660 H HG3  A GLN A 1 298 ? 28.54358  -24.44954 -28.62104 0.497 28.60140  ?  379 GLN A HG3  1 
ATOM   4661 H HG3  B GLN A 1 298 ? 29.61074  -21.41435 -29.20935 0.503 21.69219  ?  379 GLN A HG3  1 
ATOM   4662 N N    . PHE A 1 299 ? 26.74975  -20.56434 -27.90526 1.000 13.90557  ?  380 PHE A N    1 
ATOM   4663 C CA   . PHE A 1 299 ? 26.99012  -19.84674 -26.67565 1.000 13.18612  ?  380 PHE A CA   1 
ATOM   4664 C C    . PHE A 1 299 ? 25.71883  -19.55697 -25.91480 1.000 13.24339  ?  380 PHE A C    1 
ATOM   4665 O O    . PHE A 1 299 ? 25.83414  -19.08780 -24.77924 1.000 14.52902  ?  380 PHE A O    1 
ATOM   4666 C CB   . PHE A 1 299 ? 27.66985  -18.51608 -26.97317 1.000 15.25807  ?  380 PHE A CB   1 
ATOM   4667 C CG   . PHE A 1 299 ? 28.98171  -18.65471 -27.69964 1.000 17.15631  ?  380 PHE A CG   1 
ATOM   4668 C CD1  . PHE A 1 299 ? 29.98904  -19.42477 -27.17330 1.000 20.84674  ?  380 PHE A CD1  1 
ATOM   4669 C CD2  . PHE A 1 299 ? 29.18903  -17.99078 -28.89084 1.000 19.93304  ?  380 PHE A CD2  1 
ATOM   4670 C CE1  . PHE A 1 299 ? 31.20395  -19.55745 -27.85158 1.000 24.92920  ?  380 PHE A CE1  1 
ATOM   4671 C CE2  . PHE A 1 299 ? 30.41188  -18.10349 -29.55856 1.000 23.55607  ?  380 PHE A CE2  1 
ATOM   4672 C CZ   . PHE A 1 299 ? 31.39198  -18.90252 -29.03236 1.000 24.02191  ?  380 PHE A CZ   1 
ATOM   4673 H H    A PHE A 1 299 ? 26.58722  -19.95863 -28.70968 0.765 16.68669  ?  380 PHE A H    1 
ATOM   4674 D D    B PHE A 1 299 ? 26.45416  -19.97312 -28.68210 0.235 16.68669  ?  380 PHE A D    1 
ATOM   4675 H HA   . PHE A 1 299 ? 27.64992  -20.44617 -26.04841 1.000 15.82334  ?  380 PHE A HA   1 
ATOM   4676 H HB2  . PHE A 1 299 ? 27.00674  -17.91507 -27.59541 1.000 18.30969  ?  380 PHE A HB2  1 
ATOM   4677 H HB3  . PHE A 1 299 ? 27.86367  -18.00307 -26.03117 1.000 18.30969  ?  380 PHE A HB3  1 
ATOM   4678 H HD1  . PHE A 1 299 ? 29.84201  -19.93057 -26.23046 1.000 25.01608  ?  380 PHE A HD1  1 
ATOM   4679 H HD2  . PHE A 1 299 ? 28.40244  -17.38071 -29.30977 1.000 23.91965  ?  380 PHE A HD2  1 
ATOM   4680 H HE1  . PHE A 1 299 ? 31.98948  -20.17548 -27.44245 1.000 29.91504  ?  380 PHE A HE1  1 
ATOM   4681 H HE2  . PHE A 1 299 ? 30.58208  -17.56611 -30.47979 1.000 28.26728  ?  380 PHE A HE2  1 
ATOM   4682 H HZ   . PHE A 1 299 ? 32.32727  -19.01536 -29.56047 1.000 28.82629  ?  380 PHE A HZ   1 
ATOM   4683 N N    . ILE A 1 300 ? 24.53314  -19.78526 -26.49949 1.000 11.91220  ?  381 ILE A N    1 
ATOM   4684 C CA   . ILE A 1 300 ? 23.29903  -19.33734 -25.86286 1.000 10.31239  ?  381 ILE A CA   1 
ATOM   4685 C C    . ILE A 1 300 ? 22.49273  -20.55225 -25.43749 1.000 11.85521  ?  381 ILE A C    1 
ATOM   4686 O O    . ILE A 1 300 ? 22.04271  -21.34324 -26.28539 1.000 13.06346  ?  381 ILE A O    1 
ATOM   4687 C CB   . ILE A 1 300 ? 22.46399  -18.45740 -26.80358 1.000 11.78918  ?  381 ILE A CB   1 
ATOM   4688 C CG1  . ILE A 1 300 ? 23.29198  -17.27598 -27.29198 1.000 14.47741  ?  381 ILE A CG1  1 
ATOM   4689 C CG2  . ILE A 1 300 ? 21.17656  -17.98410 -26.11728 1.000 12.84037  ?  381 ILE A CG2  1 
ATOM   4690 C CD1  . ILE A 1 300 ? 22.52830  -16.36303 -28.27753 1.000 16.02455  ?  381 ILE A CD1  1 
ATOM   4691 H H    A ILE A 1 300 ? 24.40808  -20.26589 -27.39042 0.692 14.29464  ?  381 ILE A H    1 
ATOM   4692 D D    B ILE A 1 300 ? 24.41055  -20.26618 -27.39061 0.308 14.29464  ?  381 ILE A D    1 
ATOM   4693 H HA   . ILE A 1 300 ? 23.56241  -18.76847 -24.97117 1.000 12.37487  ?  381 ILE A HA   1 
ATOM   4694 H HB   . ILE A 1 300 ? 22.17650  -19.05700 -27.66725 1.000 14.14701  ?  381 ILE A HB   1 
ATOM   4695 H HG12 . ILE A 1 300 ? 23.58507  -16.67162 -26.43353 1.000 17.37289  ?  381 ILE A HG12 1 
ATOM   4696 H HG13 . ILE A 1 300 ? 24.17817  -17.65317 -27.80236 1.000 17.37289  ?  381 ILE A HG13 1 
ATOM   4697 H HG21 . ILE A 1 300 ? 21.30523  -18.05063 -25.03694 1.000 15.40844  ?  381 ILE A HG21 1 
ATOM   4698 H HG22 . ILE A 1 300 ? 20.97990  -16.95140 -26.40529 1.000 15.40844  ?  381 ILE A HG22 1 
ATOM   4699 H HG23 . ILE A 1 300 ? 20.35093  -18.62176 -26.43323 1.000 15.40844  ?  381 ILE A HG23 1 
ATOM   4700 H HD11 . ILE A 1 300 ? 21.76661  -16.95159 -28.78894 1.000 19.22946  ?  381 ILE A HD11 1 
ATOM   4701 H HD12 . ILE A 1 300 ? 22.05935  -15.55246 -27.71971 1.000 19.22946  ?  381 ILE A HD12 1 
ATOM   4702 H HD13 . ILE A 1 300 ? 23.23281  -15.95609 -29.00290 1.000 19.22946  ?  381 ILE A HD13 1 
ATOM   4703 N N    . ASP A 1 301 ? 22.30527  -20.69562 -24.12819 1.000 10.72494  ?  382 ASP A N    1 
ATOM   4704 C CA   . ASP A 1 301 ? 21.53087  -21.78960 -23.57319 1.000 11.29515  ?  382 ASP A CA   1 
ATOM   4705 C C    . ASP A 1 301 ? 20.05329  -21.61047 -23.84790 1.000 11.23403  ?  382 ASP A C    1 
ATOM   4706 O O    . ASP A 1 301 ? 19.33051  -22.59387 -24.08333 1.000 12.57132  ?  382 ASP A O    1 
ATOM   4707 C CB   . ASP A 1 301 ? 21.76024  -21.86031 -22.07376 1.000 11.87282  ?  382 ASP A CB   1 
ATOM   4708 C CG   . ASP A 1 301 ? 23.12072  -22.36751 -21.69874 1.000 12.49503  ?  382 ASP A CG   1 
ATOM   4709 O OD1  . ASP A 1 301 ? 23.71773  -23.11263 -22.50894 1.000 15.26091  ?  382 ASP A OD1  1 
ATOM   4710 O OD2  . ASP A 1 301 ? 23.55921  -22.05817 -20.60182 1.000 12.67766  -1 382 ASP A OD2  1 
ATOM   4711 H H    A ASP A 1 301 ? 22.68147  -20.06329 -23.42177 0.897 12.86993  ?  382 ASP A H    1 
ATOM   4712 D D    B ASP A 1 301 ? 22.68031  -20.06482 -23.41978 0.103 12.86993  ?  382 ASP A D    1 
ATOM   4713 H HA   . ASP A 1 301 ? 21.85980  -22.72177 -24.03249 1.000 13.55418  ?  382 ASP A HA   1 
ATOM   4714 H HB2  . ASP A 1 301 ? 21.64982  -20.86065 -21.65352 1.000 14.24739  ?  382 ASP A HB2  1 
ATOM   4715 H HB3  . ASP A 1 301 ? 21.02186  -22.53226 -21.63629 1.000 14.24739  ?  382 ASP A HB3  1 
ATOM   4716 N N    . SER A 1 302 ? 19.54789  -20.37863 -23.78338 1.000 10.93450  ?  383 SER A N    1 
ATOM   4717 C CA   . SER A 1 302 ? 18.10989  -20.15870 -23.96997 1.000 10.30580  ?  383 SER A CA   1 
ATOM   4718 C C    . SER A 1 302 ? 17.84532  -18.71771 -24.35995 1.000 10.90091  ?  383 SER A C    1 
ATOM   4719 O O    . SER A 1 302 ? 18.47815  -17.79926 -23.82477 1.000 12.54025  ?  383 SER A O    1 
ATOM   4720 C CB   . SER A 1 302 ? 17.32801  -20.52517 -22.68331 1.000 11.40419  ?  383 SER A CB   1 
ATOM   4721 O OG   . SER A 1 302 ? 15.95175  -20.59343 -22.95524 1.000 13.96852  ?  383 SER A OG   1 
ATOM   4722 H H    A SER A 1 302 ? 20.09171  -19.53366 -23.60823 0.994 13.12140  ?  383 SER A H    1 
ATOM   4723 D D    B SER A 1 302 ? 20.09170  -19.53365 -23.60823 0.006 13.12140  ?  383 SER A D    1 
ATOM   4724 H HA   . SER A 1 302 ? 17.75791  -20.78182 -24.79212 1.000 12.36696  ?  383 SER A HA   1 
ATOM   4725 H HB2  . SER A 1 302 ? 17.66962  -21.49480 -22.32105 1.000 13.68502  ?  383 SER A HB2  1 
ATOM   4726 H HB3  . SER A 1 302 ? 17.50571  -19.76085 -21.92678 1.000 13.68502  ?  383 SER A HB3  1 
ATOM   4727 N N    . ILE A 1 303 ? 16.85712  -18.53288 -25.18206 1.000 10.95760  ?  384 ILE A N    1 
ATOM   4728 C CA   . ILE A 1 303 ? 16.11863  -17.27704 -25.27864 1.000 10.68119  ?  384 ILE A CA   1 
ATOM   4729 C C    . ILE A 1 303 ? 15.09762  -17.31225 -24.15585 1.000 10.11632  ?  384 ILE A C    1 
ATOM   4730 O O    . ILE A 1 303 ? 14.46379  -18.34842 -23.92284 1.000 10.85544  ?  384 ILE A O    1 
ATOM   4731 C CB   . ILE A 1 303 ? 15.44395  -17.14267 -26.66640 1.000 11.17738  ?  384 ILE A CB   1 
ATOM   4732 C CG1  . ILE A 1 303 ? 16.54864  -17.03489 -27.71044 1.000 12.78989  ?  384 ILE A CG1  1 
ATOM   4733 C CG2  . ILE A 1 303 ? 14.48534  -15.98665 -26.65176 1.000 12.05455  ?  384 ILE A CG2  1 
ATOM   4734 C CD1  . ILE A 1 303 ? 15.99701  -17.18091 -29.10738 1.000 20.34565  ?  384 ILE A CD1  1 
ATOM   4735 H H    A ILE A 1 303 ? 16.51615  -19.24671 -25.82594 0.844 13.14912  ?  384 ILE A H    1 
ATOM   4736 D D    B ILE A 1 303 ? 16.51616  -19.24672 -25.82593 0.156 13.14912  ?  384 ILE A D    1 
ATOM   4737 H HA   . ILE A 1 303 ? 16.77860  -16.41656 -25.16851 1.000 12.81743  ?  384 ILE A HA   1 
ATOM   4738 H HB   . ILE A 1 303 ? 14.84209  -18.01564 -26.91896 1.000 13.41286  ?  384 ILE A HB   1 
ATOM   4739 H HG12 . ILE A 1 303 ? 17.02828  -16.05944 -27.62957 1.000 15.34787  ?  384 ILE A HG12 1 
ATOM   4740 H HG13 . ILE A 1 303 ? 17.28077  -17.82521 -27.54470 1.000 15.34787  ?  384 ILE A HG13 1 
ATOM   4741 H HG21 . ILE A 1 303 ? 13.80795  -16.07658 -27.50097 1.000 14.46546  ?  384 ILE A HG21 1 
ATOM   4742 H HG22 . ILE A 1 303 ? 13.91893  -16.00709 -25.72071 1.000 14.46546  ?  384 ILE A HG22 1 
ATOM   4743 H HG23 . ILE A 1 303 ? 15.04960  -15.05681 -26.72323 1.000 14.46546  ?  384 ILE A HG23 1 
ATOM   4744 H HD11 . ILE A 1 303 ? 16.82641  -17.27297 -29.80861 1.000 24.41478  ?  384 ILE A HD11 1 
ATOM   4745 H HD12 . ILE A 1 303 ? 15.37268  -18.07334 -29.15090 1.000 24.41478  ?  384 ILE A HD12 1 
ATOM   4746 H HD13 . ILE A 1 303 ? 15.40276  -16.29945 -29.34820 1.000 24.41478  ?  384 ILE A HD13 1 
ATOM   4747 N N    . VAL A 1 304 ? 14.98854  -16.18335 -23.42834 1.000 10.35174  ?  385 VAL A N    1 
ATOM   4748 C CA   . VAL A 1 304 ? 14.14991  -16.09379 -22.24402 1.000 10.42935  ?  385 VAL A CA   1 
ATOM   4749 C C    . VAL A 1 304 ? 13.32530  -14.81450 -22.29176 1.000 10.62691  ?  385 VAL A C    1 
ATOM   4750 O O    . VAL A 1 304 ? 13.57934  -13.90495 -23.08491 1.000 10.34161  ?  385 VAL A O    1 
ATOM   4751 C CB   . VAL A 1 304 ? 14.97790  -16.13464 -20.94302 1.000 10.39440  ?  385 VAL A CB   1 
ATOM   4752 C CG1  . VAL A 1 304 ? 15.55863  -17.56185 -20.74489 1.000 13.30977  ?  385 VAL A CG1  1 
ATOM   4753 C CG2  . VAL A 1 304 ? 16.06980  -15.08890 -20.93885 1.000 11.74692  ?  385 VAL A CG2  1 
ATOM   4754 H H    A VAL A 1 304 ? 15.47839  -15.31609 -23.64811 0.957 12.42208  ?  385 VAL A H    1 
ATOM   4755 D D    B VAL A 1 304 ? 15.47915  -15.31688 -23.64955 0.043 12.42208  ?  385 VAL A D    1 
ATOM   4756 H HA   . VAL A 1 304 ? 13.45743  -16.93553 -22.25000 1.000 12.51522  ?  385 VAL A HA   1 
ATOM   4757 H HB   . VAL A 1 304 ? 14.32691  -15.89990 -20.10086 1.000 12.47328  ?  385 VAL A HB   1 
ATOM   4758 H HG11 . VAL A 1 304 ? 14.76677  -18.22093 -20.38900 1.000 15.97172  ?  385 VAL A HG11 1 
ATOM   4759 H HG12 . VAL A 1 304 ? 15.94319  -17.92401 -21.69834 1.000 15.97172  ?  385 VAL A HG12 1 
ATOM   4760 H HG13 . VAL A 1 304 ? 16.36391  -17.51866 -20.01157 1.000 15.97172  ?  385 VAL A HG13 1 
ATOM   4761 H HG21 . VAL A 1 304 ? 16.87159  -15.41038 -21.60359 1.000 14.09631  ?  385 VAL A HG21 1 
ATOM   4762 H HG22 . VAL A 1 304 ? 15.65592  -14.14230 -21.28635 1.000 14.09631  ?  385 VAL A HG22 1 
ATOM   4763 H HG23 . VAL A 1 304 ? 16.45076  -14.97766 -19.92366 1.000 14.09631  ?  385 VAL A HG23 1 
ATOM   4764 N N    . TRP A 1 305 ? 12.28189  -14.76885 -21.42979 1.000 9.84232   ?  386 TRP A N    1 
ATOM   4765 C CA   . TRP A 1 305 ? 11.54248  -13.52869 -21.18019 1.000 9.51492   ?  386 TRP A CA   1 
ATOM   4766 C C    . TRP A 1 305 ? 11.80293  -13.17524 -19.73657 1.000 9.62718   ?  386 TRP A C    1 
ATOM   4767 O O    . TRP A 1 305 ? 11.20359  -13.77237 -18.82940 1.000 11.06733  ?  386 TRP A O    1 
ATOM   4768 C CB   . TRP A 1 305 ? 10.06077  -13.71459 -21.41420 1.000 11.48589  ?  386 TRP A CB   1 
ATOM   4769 C CG   . TRP A 1 305 ? 9.65350   -13.69613 -22.85905 1.000 10.91274  ?  386 TRP A CG   1 
ATOM   4770 C CD1  . TRP A 1 305 ? 10.44567  -13.83830 -23.93655 1.000 9.62226   ?  386 TRP A CD1  1 
ATOM   4771 C CD2  . TRP A 1 305 ? 8.30558   -13.53022 -23.34999 1.000 11.10916  ?  386 TRP A CD2  1 
ATOM   4772 N NE1  . TRP A 1 305 ? 9.67587   -13.76490 -25.11031 1.000 11.58406  ?  386 TRP A NE1  1 
ATOM   4773 C CE2  . TRP A 1 305 ? 8.36614   -13.57797 -24.75805 1.000 12.01147  ?  386 TRP A CE2  1 
ATOM   4774 C CE3  . TRP A 1 305 ? 7.08993   -13.33303 -22.72842 1.000 13.55387  ?  386 TRP A CE3  1 
ATOM   4775 C CZ2  . TRP A 1 305 ? 7.24501   -13.43600 -25.56099 1.000 13.62658  ?  386 TRP A CZ2  1 
ATOM   4776 C CZ3  . TRP A 1 305 ? 5.94330   -13.19165 -23.54064 1.000 14.79397  ?  386 TRP A CZ3  1 
ATOM   4777 C CH2  . TRP A 1 305 ? 6.04846   -13.27067 -24.92373 1.000 15.62229  ?  386 TRP A CH2  1 
ATOM   4778 H H    A TRP A 1 305 ? 11.93953  -15.57195 -20.90232 0.622 11.81078  ?  386 TRP A H    1 
ATOM   4779 D D    B TRP A 1 305 ? 11.94134  -15.57343 -20.90340 0.378 11.81078  ?  386 TRP A D    1 
ATOM   4780 H HA   . TRP A 1 305 ? 11.89875  -12.73986 -21.84270 1.000 11.41791  ?  386 TRP A HA   1 
ATOM   4781 H HB2  . TRP A 1 305 ? 9.76148   -14.67732 -20.99984 1.000 13.78306  ?  386 TRP A HB2  1 
ATOM   4782 H HB3  . TRP A 1 305 ? 9.52560   -12.90945 -20.91077 1.000 13.78306  ?  386 TRP A HB3  1 
ATOM   4783 H HD1  . TRP A 1 305 ? 11.51493  -13.98685 -23.90468 1.000 11.54672  ?  386 TRP A HD1  1 
ATOM   4784 H HE1  A TRP A 1 305 ? 10.03258  -13.83843 -26.06307 0.958 13.90088  ?  386 TRP A HE1  1 
ATOM   4785 D DE1  B TRP A 1 305 ? 10.03258  -13.83843 -26.06307 0.042 13.90088  ?  386 TRP A DE1  1 
ATOM   4786 H HE3  . TRP A 1 305 ? 7.01718   -13.28808 -21.65181 1.000 16.26465  ?  386 TRP A HE3  1 
ATOM   4787 H HZ2  . TRP A 1 305 ? 7.31447   -13.45521 -26.63858 1.000 16.35189  ?  386 TRP A HZ2  1 
ATOM   4788 H HZ3  . TRP A 1 305 ? 4.97947   -13.02118 -23.08416 1.000 17.75277  ?  386 TRP A HZ3  1 
ATOM   4789 H HH2  . TRP A 1 305 ? 5.14940   -13.19859 -25.51779 1.000 18.74675  ?  386 TRP A HH2  1 
ATOM   4790 N N    . VAL A 1 306 ? 12.72993  -12.23896 -19.49146 1.000 10.04511  ?  387 VAL A N    1 
ATOM   4791 C CA   . VAL A 1 306 ? 13.13797  -11.90942 -18.12355 1.000 8.85082   ?  387 VAL A CA   1 
ATOM   4792 C C    . VAL A 1 306 ? 12.23026  -10.80810 -17.59519 1.000 10.11886  ?  387 VAL A C    1 
ATOM   4793 O O    . VAL A 1 306 ? 11.52398  -11.01450 -16.60156 1.000 10.67553  ?  387 VAL A O    1 
ATOM   4794 C CB   . VAL A 1 306 ? 14.62516  -11.54936 -18.02247 1.000 9.74655   ?  387 VAL A CB   1 
ATOM   4795 C CG1  . VAL A 1 306 ? 14.96685  -11.39673 -16.54878 1.000 12.65267  ?  387 VAL A CG1  1 
ATOM   4796 C CG2  . VAL A 1 306 ? 15.50078  -12.66713 -18.62623 1.000 12.07456  ?  387 VAL A CG2  1 
ATOM   4797 H H    A VAL A 1 306 ? 13.20896  -11.69957 -20.21257 0.741 12.05413  ?  387 VAL A H    1 
ATOM   4798 D D    B VAL A 1 306 ? 13.20870  -11.69981 -20.21292 0.259 12.05413  ?  387 VAL A D    1 
ATOM   4799 H HA   . VAL A 1 306 ? 13.00179  -12.78791 -17.49284 1.000 10.62098  ?  387 VAL A HA   1 
ATOM   4800 H HB   . VAL A 1 306 ? 14.82242  -10.62790 -18.57029 1.000 11.69586  ?  387 VAL A HB   1 
ATOM   4801 H HG11 . VAL A 1 306 ? 16.05045  -11.41381 -16.43212 1.000 15.18320  ?  387 VAL A HG11 1 
ATOM   4802 H HG12 . VAL A 1 306 ? 14.56914  -10.44789 -16.18871 1.000 15.18320  ?  387 VAL A HG12 1 
ATOM   4803 H HG13 . VAL A 1 306 ? 14.52019  -12.22161 -15.99365 1.000 15.18320  ?  387 VAL A HG13 1 
ATOM   4804 H HG21 . VAL A 1 306 ? 15.68370  -13.42510 -17.86458 1.000 14.48947  ?  387 VAL A HG21 1 
ATOM   4805 H HG22 . VAL A 1 306 ? 14.97669  -13.11008 -19.47312 1.000 14.48947  ?  387 VAL A HG22 1 
ATOM   4806 H HG23 . VAL A 1 306 ? 16.44612  -12.23744 -18.95759 1.000 14.48947  ?  387 VAL A HG23 1 
ATOM   4807 N N    . LYS A 1 307 ? 12.24273  -9.64209  -18.21659 1.000 9.75017   ?  388 LYS A N    1 
ATOM   4808 C CA   . LYS A 1 307 ? 11.28274  -8.59216  -17.88038 1.000 10.51097  ?  388 LYS A CA   1 
ATOM   4809 C C    . LYS A 1 307 ? 9.88360   -8.95550  -18.33836 1.000 12.38899  ?  388 LYS A C    1 
ATOM   4810 O O    . LYS A 1 307 ? 9.69563   -9.28794  -19.51386 1.000 12.97400  ?  388 LYS A O    1 
ATOM   4811 C CB   . LYS A 1 307 ? 11.75783  -7.29345  -18.56271 1.000 12.03436  ?  388 LYS A CB   1 
ATOM   4812 C CG   . LYS A 1 307 ? 10.74117  -6.13578  -18.62438 1.000 14.46654  ?  388 LYS A CG   1 
ATOM   4813 C CD   . LYS A 1 307 ? 10.52072  -5.47227  -17.30409 1.000 14.73932  ?  388 LYS A CD   1 
ATOM   4814 C CE   . LYS A 1 307 ? 9.38647   -4.44440  -17.41970 1.000 16.22372  ?  388 LYS A CE   1 
ATOM   4815 N NZ   . LYS A 1 307 ? 9.20306   -3.61168  -16.20101 1.000 17.87673  ?  388 LYS A NZ   1 
ATOM   4816 H H    A LYS A 1 307 ? 12.89850  -9.38677  -18.95495 0.632 11.70021  ?  388 LYS A H    1 
ATOM   4817 D D    B LYS A 1 307 ? 12.89765  -9.38501  -18.95509 0.368 11.70021  ?  388 LYS A D    1 
ATOM   4818 H HA   . LYS A 1 307 ? 11.22650  -8.45673  -16.80029 1.000 12.61317  ?  388 LYS A HA   1 
ATOM   4819 H HB2  . LYS A 1 307 ? 12.62845  -6.92527  -18.01997 1.000 14.44123  ?  388 LYS A HB2  1 
ATOM   4820 H HB3  . LYS A 1 307 ? 12.03255  -7.53223  -19.59013 1.000 14.44123  ?  388 LYS A HB3  1 
ATOM   4821 H HG2  . LYS A 1 307 ? 11.10691  -5.38104  -19.32058 1.000 17.35985  ?  388 LYS A HG2  1 
ATOM   4822 H HG3  . LYS A 1 307 ? 9.78243   -6.52533  -18.96667 1.000 17.35985  ?  388 LYS A HG3  1 
ATOM   4823 H HD2  . LYS A 1 307 ? 10.24300  -6.21805  -16.55925 1.000 17.68718  ?  388 LYS A HD2  1 
ATOM   4824 H HD3  . LYS A 1 307 ? 11.43010  -4.95707  -16.99474 1.000 17.68718  ?  388 LYS A HD3  1 
ATOM   4825 H HE2  . LYS A 1 307 ? 9.60480   -3.77309  -18.25022 1.000 19.46846  ?  388 LYS A HE2  1 
ATOM   4826 H HE3  . LYS A 1 307 ? 8.45130   -4.97326  -17.60375 1.000 19.46846  ?  388 LYS A HE3  1 
ATOM   4827 N N    . PRO A 1 308 ? 8.87688   -8.95056  -17.44475 1.000 11.79747  ?  389 PRO A N    1 
ATOM   4828 C CA   . PRO A 1 308 ? 7.52244   -9.35109  -17.86187 1.000 12.52465  ?  389 PRO A CA   1 
ATOM   4829 C C    . PRO A 1 308 ? 6.84351   -8.18379  -18.56327 1.000 13.35224  ?  389 PRO A C    1 
ATOM   4830 O O    . PRO A 1 308 ? 6.54571   -7.15859  -17.94513 1.000 14.32911  ?  389 PRO A O    1 
ATOM   4831 C CB   . PRO A 1 308 ? 6.83457   -9.69953  -16.53895 1.000 16.90602  ?  389 PRO A CB   1 
ATOM   4832 C CG   . PRO A 1 308 ? 7.90857   -9.79010  -15.51737 1.000 18.76489  ?  389 PRO A CG   1 
ATOM   4833 C CD   . PRO A 1 308 ? 8.98763   -8.86220  -15.97838 1.000 14.23604  ?  389 PRO A CD   1 
ATOM   4834 H HA   . PRO A 1 308 ? 7.54161   -10.23287 -18.50233 1.000 15.02958  ?  389 PRO A HA   1 
ATOM   4835 H HB2  . PRO A 1 308 ? 6.12364   -8.91482  -16.28028 1.000 20.28722  ?  389 PRO A HB2  1 
ATOM   4836 H HB3  . PRO A 1 308 ? 6.31701   -10.65371 -16.63774 1.000 20.28722  ?  389 PRO A HB3  1 
ATOM   4837 H HG2  . PRO A 1 308 ? 7.52067   -9.47984  -14.54712 1.000 22.51787  ?  389 PRO A HG2  1 
ATOM   4838 H HG3  . PRO A 1 308 ? 8.27758   -10.81420 -15.46118 1.000 22.51787  ?  389 PRO A HG3  1 
ATOM   4839 H HD2  . PRO A 1 308 ? 8.80374   -7.84508  -15.63235 1.000 17.08324  ?  389 PRO A HD2  1 
ATOM   4840 H HD3  . PRO A 1 308 ? 9.96653   -9.20035  -15.63851 1.000 17.08324  ?  389 PRO A HD3  1 
ATOM   4841 N N    . GLY A 1 309 ? 6.55718   -8.36568  -19.85877 1.000 13.22809  ?  390 GLY A N    1 
ATOM   4842 C CA   . GLY A 1 309 ? 5.92202   -7.31309  -20.62665 1.000 15.50162  ?  390 GLY A CA   1 
ATOM   4843 C C    . GLY A 1 309 ? 4.55371   -6.94770  -20.11664 1.000 14.95741  ?  390 GLY A C    1 
ATOM   4844 O O    . GLY A 1 309 ? 3.72225   -7.80877  -19.82303 1.000 15.37619  ?  390 GLY A O    1 
ATOM   4845 H H    A GLY A 1 309 ? 6.75315   -9.21762  -20.38431 0.758 15.87370  ?  390 GLY A H    1 
ATOM   4846 D D    B GLY A 1 309 ? 6.75294   -9.21740  -20.38475 0.242 15.87370  ?  390 GLY A D    1 
ATOM   4847 H HA2  . GLY A 1 309 ? 6.54649   -6.42035  -20.59271 1.000 18.60194  ?  390 GLY A HA2  1 
ATOM   4848 H HA3  . GLY A 1 309 ? 5.82272   -7.63753  -21.66250 1.000 18.60194  ?  390 GLY A HA3  1 
ATOM   4849 N N    . GLY A 1 310 ? 4.35274   -5.64758  -19.94438 1.000 13.46396  ?  391 GLY A N    1 
ATOM   4850 C CA   . GLY A 1 310 ? 3.12998   -5.10805  -19.36146 1.000 15.08279  ?  391 GLY A CA   1 
ATOM   4851 C C    . GLY A 1 310 ? 3.33627   -4.45921  -18.01229 1.000 15.09584  ?  391 GLY A C    1 
ATOM   4852 O O    . GLY A 1 310 ? 2.54392   -3.60861  -17.61141 1.000 18.26763  ?  391 GLY A O    1 
ATOM   4853 H H    A GLY A 1 310 ? 5.03085   -4.93106  -20.20355 0.570 16.15675  ?  391 GLY A H    1 
ATOM   4854 D D    B GLY A 1 310 ? 5.03283   -4.93332  -20.20458 0.430 16.15675  ?  391 GLY A D    1 
ATOM   4855 H HA2  . GLY A 1 310 ? 2.71550   -4.35932  -20.03651 1.000 18.09935  ?  391 GLY A HA2  1 
ATOM   4856 H HA3  . GLY A 1 310 ? 2.40800   -5.91572  -19.24099 1.000 18.09935  ?  391 GLY A HA3  1 
ATOM   4857 N N    . GLU A 1 311 ? 4.34881   -4.87936  -17.28086 1.000 13.95843  ?  392 GLU A N    1 
ATOM   4858 C CA   . GLU A 1 311 ? 4.70740   -4.22650  -16.04385 1.000 13.46672  ?  392 GLU A CA   1 
ATOM   4859 C C    . GLU A 1 311 ? 5.56765   -3.01316  -16.36960 1.000 14.41336  ?  392 GLU A C    1 
ATOM   4860 O O    . GLU A 1 311 ? 6.54080   -3.11686  -17.11969 1.000 15.27048  ?  392 GLU A O    1 
ATOM   4861 C CB   . GLU A 1 311 ? 5.46373   -5.20960  -15.12790 1.000 14.70238  ?  392 GLU A CB   1 
ATOM   4862 C CG   . GLU A 1 311 ? 4.60756   -6.40246  -14.69155 1.000 15.57999  ?  392 GLU A CG   1 
ATOM   4863 C CD   . GLU A 1 311 ? 5.30058   -7.37936  -13.77209 1.000 16.32833  ?  392 GLU A CD   1 
ATOM   4864 O OE1  . GLU A 1 311 ? 6.46998   -7.12504  -13.42633 1.000 20.45504  ?  392 GLU A OE1  1 
ATOM   4865 O OE2  . GLU A 1 311 ? 4.66687   -8.39929  -13.43226 1.000 18.66603  -1 392 GLU A OE2  1 
ATOM   4866 H H    A GLU A 1 311 ? 4.94247   -5.67349  -17.52029 0.594 16.75011  ?  392 GLU A H    1 
ATOM   4867 D D    B GLU A 1 311 ? 4.94267   -5.67343  -17.51998 0.406 16.75011  ?  392 GLU A D    1 
ATOM   4868 H HA   . GLU A 1 311 ? 3.81879   -3.89493  -15.50670 1.000 16.16007  ?  392 GLU A HA   1 
ATOM   4869 H HB2  . GLU A 1 311 ? 6.33066   -5.59619  -15.66371 1.000 17.64285  ?  392 GLU A HB2  1 
ATOM   4870 H HB3  . GLU A 1 311 ? 5.78536   -4.68063  -14.23077 1.000 17.64285  ?  392 GLU A HB3  1 
ATOM   4871 H HG2  . GLU A 1 311 ? 3.73040   -6.02493  -14.16604 1.000 18.69599  ?  392 GLU A HG2  1 
ATOM   4872 H HG3  . GLU A 1 311 ? 4.30105   -6.95227  -15.58142 1.000 18.69599  ?  392 GLU A HG3  1 
ATOM   4873 N N    . CYS A 1 312 ? 5.18077   -1.85354  -15.84291 1.000 14.60013  ?  393 CYS A N    1 
ATOM   4874 C CA   . CYS A 1 312 ? 5.72922   -0.59628  -16.29290 1.000 14.37221  ?  393 CYS A CA   1 
ATOM   4875 C C    . CYS A 1 312 ? 7.19327   -0.46070  -15.86312 1.000 14.89436  ?  393 CYS A C    1 
ATOM   4876 O O    . CYS A 1 312 ? 7.61454   -0.99866  -14.84097 1.000 17.11702  ?  393 CYS A O    1 
ATOM   4877 C CB   . CYS A 1 312 ? 4.90287   0.52568   -15.65471 1.000 15.65102  ?  393 CYS A CB   1 
ATOM   4878 S SG   . CYS A 1 312 ? 5.23699   2.10470   -16.37274 1.000 16.43755  ?  393 CYS A SG   1 
ATOM   4879 H H    A CYS A 1 312 ? 4.48672   -1.76058  -15.10125 0.680 17.52016  ?  393 CYS A H    1 
ATOM   4880 D D    B CYS A 1 312 ? 4.48688   -1.75914  -15.10128 0.320 17.52016  ?  393 CYS A D    1 
ATOM   4881 H HA   . CYS A 1 312 ? 5.69535   -0.52105  -17.37978 1.000 17.24666  ?  393 CYS A HA   1 
ATOM   4882 H HB2  . CYS A 1 312 ? 3.84343   0.30881   -15.79126 1.000 18.78123  ?  393 CYS A HB2  1 
ATOM   4883 H HB3  . CYS A 1 312 ? 5.13827   0.58024   -14.59184 1.000 18.78123  ?  393 CYS A HB3  1 
ATOM   4884 N N    . ASP A 1 313 ? 7.97264   0.25498   -16.65691 1.000 13.84929  ?  394 ASP A N    1 
ATOM   4885 C CA   . ASP A 1 313 ? 9.37265   0.50937   -16.37757 1.000 14.52103  ?  394 ASP A CA   1 
ATOM   4886 C C    . ASP A 1 313 ? 9.55595   1.73557   -15.48854 1.000 17.55368  ?  394 ASP A C    1 
ATOM   4887 O O    . ASP A 1 313 ? 10.63326  1.91754   -14.91332 1.000 17.84718  ?  394 ASP A O    1 
ATOM   4888 C CB   . ASP A 1 313 ? 10.16713  0.77465   -17.66241 1.000 15.34165  ?  394 ASP A CB   1 
ATOM   4889 C CG   . ASP A 1 313 ? 10.22911  -0.39964  -18.60243 1.000 16.49578  ?  394 ASP A CG   1 
ATOM   4890 O OD1  . ASP A 1 313 ? 10.28256  -1.54246  -18.10828 1.000 18.36186  ?  394 ASP A OD1  1 
ATOM   4891 O OD2  . ASP A 1 313 ? 10.21163  -0.15878  -19.82292 1.000 14.53192  -1 394 ASP A OD2  1 
ATOM   4892 H H    A ASP A 1 313 ? 7.65421   0.68410   -17.52574 0.545 16.61915  ?  394 ASP A H    1 
ATOM   4893 D D    B ASP A 1 313 ? 7.65428   0.68413   -17.52575 0.455 16.61915  ?  394 ASP A D    1 
ATOM   4894 H HA   . ASP A 1 313 ? 9.78289   -0.38155  -15.90211 1.000 17.42524  ?  394 ASP A HA   1 
ATOM   4895 H HB2  . ASP A 1 313 ? 9.69993   1.60154   -18.19727 1.000 18.40998  ?  394 ASP A HB2  1 
ATOM   4896 H HB3  . ASP A 1 313 ? 11.19033  1.03595   -17.39246 1.000 18.40998  ?  394 ASP A HB3  1 
ATOM   4897 N N    . GLY A 1 314 ? 8.56543   2.62048   -15.42513 1.000 17.13222  ?  395 GLY A N    1 
ATOM   4898 C CA   . GLY A 1 314 ? 8.69674   3.85995   -14.68877 1.000 17.64726  ?  395 GLY A CA   1 
ATOM   4899 C C    . GLY A 1 314 ? 7.64344   4.86279   -15.10858 1.000 20.49115  ?  395 GLY A C    1 
ATOM   4900 O O    . GLY A 1 314 ? 7.07127   4.80944   -16.18623 1.000 16.31242  ?  395 GLY A O    1 
ATOM   4901 H H    A GLY A 1 314 ? 7.65883   2.50130   -15.87710 0.513 20.55866  ?  395 GLY A H    1 
ATOM   4902 D D    B GLY A 1 314 ? 7.65882   2.50135   -15.87708 0.487 20.55866  ?  395 GLY A D    1 
ATOM   4903 H HA2  . GLY A 1 314 ? 8.58682   3.66521   -13.62196 1.000 21.17671  ?  395 GLY A HA2  1 
ATOM   4904 H HA3  . GLY A 1 314 ? 9.68094   4.29145   -14.87118 1.000 21.17671  ?  395 GLY A HA3  1 
ATOM   4905 N N    . THR A 1 315 ? 7.37020   5.80582   -14.21058 1.000 19.34871  ?  396 THR A N    1 
ATOM   4906 C CA   . THR A 1 315 ? 6.27818   6.74098   -14.43180 1.000 19.93116  ?  396 THR A CA   1 
ATOM   4907 C C    . THR A 1 315 ? 6.72935   7.91864   -15.27603 1.000 18.99889  ?  396 THR A C    1 
ATOM   4908 O O    . THR A 1 315 ? 7.88091   8.34083   -15.25120 1.000 20.55290  ?  396 THR A O    1 
ATOM   4909 C CB   . THR A 1 315 ? 5.68655   7.24016   -13.09814 1.000 19.70732  ?  396 THR A CB   1 
ATOM   4910 O OG1  . THR A 1 315 ? 4.52274   8.01649   -13.37464 1.000 22.60739  ?  396 THR A OG1  1 
ATOM   4911 C CG2  . THR A 1 315 ? 6.68342   8.06874   -12.32801 1.000 24.36478  ?  396 THR A CG2  1 
ATOM   4912 H H    A THR A 1 315 ? 7.87881   5.94321   -13.33718 0.592 23.21845  ?  396 THR A H    1 
ATOM   4913 D D    B THR A 1 315 ? 7.87847   5.94365   -13.33705 0.408 23.21845  ?  396 THR A D    1 
ATOM   4914 H HA   . THR A 1 315 ? 5.48325   6.22531   -14.97056 1.000 23.91739  ?  396 THR A HA   1 
ATOM   4915 H HB   . THR A 1 315 ? 5.42606   6.38698   -12.47177 1.000 23.64879  ?  396 THR A HB   1 
ATOM   4916 H HG21 . THR A 1 315 ? 6.83079   9.02907   -12.82211 1.000 29.23773  ?  396 THR A HG21 1 
ATOM   4917 H HG22 . THR A 1 315 ? 6.31950   8.24398   -11.31560 1.000 29.23773  ?  396 THR A HG22 1 
ATOM   4918 H HG23 . THR A 1 315 ? 7.63939   7.54777   -12.27505 1.000 29.23773  ?  396 THR A HG23 1 
ATOM   4919 N N    . SER A 1 316 ? 5.76811   8.47056   -16.02374 1.000 18.09641  ?  397 SER A N    1 
ATOM   4920 C CA   . SER A 1 316 ? 5.95081   9.72467   -16.73411 1.000 19.26137  ?  397 SER A CA   1 
ATOM   4921 C C    . SER A 1 316 ? 5.50902   10.94085  -15.91916 1.000 22.90923  ?  397 SER A C    1 
ATOM   4922 O O    . SER A 1 316 ? 5.60832   12.06297  -16.41310 1.000 24.59249  ?  397 SER A O    1 
ATOM   4923 C CB   . SER A 1 316 ? 5.18100   9.66841   -18.06099 1.000 23.27963  ?  397 SER A CB   1 
ATOM   4924 O OG   . SER A 1 316 ? 3.81104   9.52437   -17.85709 1.000 20.34347  ?  397 SER A OG   1 
ATOM   4925 H H    A SER A 1 316 ? 4.84303   8.06082   -16.15311 0.759 21.71569  ?  397 SER A H    1 
ATOM   4926 D D    B SER A 1 316 ? 4.84336   8.05984   -16.15236 0.241 21.71569  ?  397 SER A D    1 
ATOM   4927 H HA   . SER A 1 316 ? 7.00820   9.86075   -16.96108 1.000 23.11364  ?  397 SER A HA   1 
ATOM   4928 H HB2  . SER A 1 316 ? 5.35865   10.59371  -18.60904 1.000 27.93555  ?  397 SER A HB2  1 
ATOM   4929 H HB3  . SER A 1 316 ? 5.54087   8.81754   -18.63945 1.000 27.93555  ?  397 SER A HB3  1 
ATOM   4930 N N    . ASN A 1 317 ? 5.06397   10.74221  -14.68431 1.000 20.09819  ?  398 ASN A N    1 
ATOM   4931 C CA   . ASN A 1 317 ? 4.50902   11.82473  -13.85863 1.000 24.72522  ?  398 ASN A CA   1 
ATOM   4932 C C    . ASN A 1 317 ? 5.66725   12.54677  -13.18376 1.000 23.25921  ?  398 ASN A C    1 
ATOM   4933 O O    . ASN A 1 317 ? 6.34084   11.97851  -12.32338 1.000 24.59325  ?  398 ASN A O    1 
ATOM   4934 C CB   . ASN A 1 317 ? 3.52720   11.21056  -12.86290 1.000 24.51292  ?  398 ASN A CB   1 
ATOM   4935 C CG   . ASN A 1 317 ? 3.03616   12.20715  -11.83891 1.000 37.54572  ?  398 ASN A CG   1 
ATOM   4936 O OD1  . ASN A 1 317 ? 3.15111   13.41359  -12.03122 1.000 27.97212  ?  398 ASN A OD1  1 
ATOM   4937 N ND2  . ASN A 1 317 ? 2.51261   11.70019  -10.72386 1.000 36.69978  ?  398 ASN A ND2  1 
ATOM   4938 H H    A ASN A 1 317 ? 5.07095   9.83627   -14.21567 0.791 24.11783  ?  398 ASN A H    1 
ATOM   4939 D D    B ASN A 1 317 ? 5.07117   9.83604   -14.21612 0.209 24.11783  ?  398 ASN A D    1 
ATOM   4940 H HA   . ASN A 1 317 ? 3.97440   12.56362  -14.45556 1.000 29.67026  ?  398 ASN A HA   1 
ATOM   4941 H HB2  . ASN A 1 317 ? 2.66179   10.83011  -13.40551 1.000 29.41550  ?  398 ASN A HB2  1 
ATOM   4942 H HB3  . ASN A 1 317 ? 4.02150   10.39700  -12.33195 1.000 29.41550  ?  398 ASN A HB3  1 
ATOM   4943 N N    . SER A 1 318 ? 5.89865   13.80409  -13.57077 1.000 25.71824  ?  399 SER A N    1 
ATOM   4944 C CA   . SER A 1 318 ? 7.06878   14.52903  -13.07209 1.000 26.36080  ?  399 SER A CA   1 
ATOM   4945 C C    . SER A 1 318 ? 6.92668   14.94803  -11.60775 1.000 24.09656  ?  399 SER A C    1 
ATOM   4946 O O    . SER A 1 318 ? 7.93047   15.31155  -11.00015 1.000 34.17805  ?  399 SER A O    1 
ATOM   4947 C CB   . SER A 1 318 ? 7.38231   15.72169  -13.95980 1.000 31.15125  ?  399 SER A CB   1 
ATOM   4948 O OG   . SER A 1 318 ? 6.22194   16.51490  -14.16087 1.000 33.26319  ?  399 SER A OG   1 
ATOM   4949 H H    A SER A 1 318 ? 5.30935   14.33464  -14.21236 0.754 30.86188  ?  399 SER A H    1 
ATOM   4950 D D    B SER A 1 318 ? 5.30994   14.33539  -14.21228 0.246 30.86188  ?  399 SER A D    1 
ATOM   4951 H HA   . SER A 1 318 ? 7.93611   13.87139  -13.13000 1.000 31.63296  ?  399 SER A HA   1 
ATOM   4952 H HB2  . SER A 1 318 ? 8.15005   16.32945  -13.48095 1.000 37.38150  ?  399 SER A HB2  1 
ATOM   4953 H HB3  . SER A 1 318 ? 7.73934   15.36257  -14.92503 1.000 37.38150  ?  399 SER A HB3  1 
ATOM   4954 N N    . SER A 1 319 ? 5.74528   14.84914  -11.03116 1.000 23.42910  ?  400 SER A N    1 
ATOM   4955 C CA   . SER A 1 319 ? 5.54619   15.03476  -9.59885  1.000 30.30151  ?  400 SER A CA   1 
ATOM   4956 C C    . SER A 1 319 ? 5.83235   13.78597  -8.77210  1.000 32.67310  ?  400 SER A C    1 
ATOM   4957 O O    . SER A 1 319 ? 5.76528   13.84533  -7.53238  1.000 29.85846  ?  400 SER A O    1 
ATOM   4958 C CB   . SER A 1 319 ? 4.09993   15.46102  -9.33192  1.000 30.87686  ?  400 SER A CB   1 
ATOM   4959 O OG   . SER A 1 319 ? 3.81133   16.68051  -9.99155  1.000 42.69308  ?  400 SER A OG   1 
ATOM   4960 H H    A SER A 1 319 ? 4.88385   14.63706  -11.53452 0.776 28.11492  ?  400 SER A H    1 
ATOM   4961 D D    B SER A 1 319 ? 4.88408   14.63704  -11.53491 0.224 28.11492  ?  400 SER A D    1 
ATOM   4962 H HA   . SER A 1 319 ? 6.22518   15.82109  -9.26905  1.000 36.36181  ?  400 SER A HA   1 
ATOM   4963 H HB2  . SER A 1 319 ? 3.42667   14.68787  -9.70212  1.000 37.05223  ?  400 SER A HB2  1 
ATOM   4964 H HB3  . SER A 1 319 ? 3.96023   15.59462  -8.25920  1.000 37.05223  ?  400 SER A HB3  1 
ATOM   4965 N N    . SER A 1 320 ? 6.13429   12.66407  -9.39656  1.000 34.02096  ?  401 SER A N    1 
ATOM   4966 C CA   . SER A 1 320 ? 6.38757   11.50100  -8.56597  1.000 31.47729  ?  401 SER A CA   1 
ATOM   4967 C C    . SER A 1 320 ? 7.78376   11.60487  -7.96761  1.000 24.61339  ?  401 SER A C    1 
ATOM   4968 O O    . SER A 1 320 ? 8.69649   12.12590  -8.61239  1.000 29.83767  ?  401 SER A O    1 
ATOM   4969 C CB   . SER A 1 320 ? 6.30760   10.21350  -9.38182  1.000 33.24187  ?  401 SER A CB   1 
ATOM   4970 O OG   . SER A 1 320 ? 6.77451   9.11435   -8.58625  1.000 28.24580  ?  401 SER A OG   1 
ATOM   4971 H H    A SER A 1 320 ? 6.20703   12.53457  -10.40569 0.703 40.82515  ?  401 SER A H    1 
ATOM   4972 D D    B SER A 1 320 ? 6.20743   12.53288  -10.40544 0.297 40.82515  ?  401 SER A D    1 
ATOM   4973 H HA   . SER A 1 320 ? 5.64063   11.45175  -7.77366  1.000 37.77275  ?  401 SER A HA   1 
ATOM   4974 H HB2  . SER A 1 320 ? 5.27268   10.03436  -9.67327  1.000 39.89025  ?  401 SER A HB2  1 
ATOM   4975 H HB3  . SER A 1 320 ? 6.93362   10.30871  -10.26903 1.000 39.89025  ?  401 SER A HB3  1 
ATOM   4976 N N    A PRO A 1 321 ? 7.94121   11.18221  -6.70674  0.619 29.91787  ?  402 PRO A N    1 
ATOM   4977 N N    B PRO A 1 321 ? 8.00944   11.06264  -6.78684  0.381 29.95140  ?  402 PRO A N    1 
ATOM   4978 C CA   A PRO A 1 321 ? 9.29032   11.09198  -6.12699  0.619 32.53443  ?  402 PRO A CA   1 
ATOM   4979 C CA   B PRO A 1 321 ? 9.38699   11.05013  -6.26755  0.381 32.56886  ?  402 PRO A CA   1 
ATOM   4980 C C    A PRO A 1 321 ? 10.09763  9.96518   -6.73130  0.619 35.03386  ?  402 PRO A C    1 
ATOM   4981 C C    B PRO A 1 321 ? 10.39006  10.41115  -7.22452  0.381 34.35773  ?  402 PRO A C    1 
ATOM   4982 O O    A PRO A 1 321 ? 11.32138  9.94348   -6.55888  0.619 36.94064  ?  402 PRO A O    1 
ATOM   4983 O O    B PRO A 1 321 ? 11.59065  10.68379  -7.12753  0.381 31.49835  ?  402 PRO A O    1 
ATOM   4984 C CB   A PRO A 1 321 ? 9.01935   10.85139  -4.63234  0.619 29.31548  ?  402 PRO A CB   1 
ATOM   4985 C CB   B PRO A 1 321 ? 9.26502   10.26156  -4.95266  0.381 33.14275  ?  402 PRO A CB   1 
ATOM   4986 C CG   A PRO A 1 321 ? 7.70677   10.10866  -4.61667  0.619 33.08135  ?  402 PRO A CG   1 
ATOM   4987 C CG   B PRO A 1 321 ? 7.83152   10.44774  -4.53139  0.381 32.25014  ?  402 PRO A CG   1 
ATOM   4988 C CD   A PRO A 1 321 ? 6.89894   10.69613  -5.77496  0.619 30.54746  ?  402 PRO A CD   1 
ATOM   4989 C CD   B PRO A 1 321 ? 7.03488   10.51907  -5.81898  0.381 31.17911  ?  402 PRO A CD   1 
ATOM   4990 H HA   A PRO A 1 321 ? 9.82668   12.03463  -6.23575  0.619 39.04132  ?  402 PRO A HA   1 
ATOM   4991 H HA   B PRO A 1 321 ? 9.71050   12.06819  -6.05078  0.381 39.08263  ?  402 PRO A HA   1 
ATOM   4992 H HB2  A PRO A 1 321 ? 9.81795   10.25035  -4.19750  0.619 35.17858  ?  402 PRO A HB2  1 
ATOM   4993 H HB2  B PRO A 1 321 ? 9.48878   9.20908   -5.12677  0.381 39.77130  ?  402 PRO A HB2  1 
ATOM   4994 H HB3  A PRO A 1 321 ? 8.94047   11.80299  -4.10666  0.619 35.17858  ?  402 PRO A HB3  1 
ATOM   4995 H HB3  B PRO A 1 321 ? 9.94846   10.66978  -4.20811  0.381 39.77130  ?  402 PRO A HB3  1 
ATOM   4996 H HG2  A PRO A 1 321 ? 7.88212   9.04329   -4.76614  0.619 39.69762  ?  402 PRO A HG2  1 
ATOM   4997 H HG2  B PRO A 1 321 ? 7.51218   9.60017   -3.92498  0.381 38.70017  ?  402 PRO A HG2  1 
ATOM   4998 H HG3  A PRO A 1 321 ? 7.19931   10.27319  -3.66614  0.619 39.69762  ?  402 PRO A HG3  1 
ATOM   4999 H HG3  B PRO A 1 321 ? 7.73131   11.37203  -3.96240  0.381 38.70017  ?  402 PRO A HG3  1 
ATOM   5000 H HD2  A PRO A 1 321 ? 6.28404   9.92971   -6.24676  0.619 36.65695  ?  402 PRO A HD2  1 
ATOM   5001 H HD2  B PRO A 1 321 ? 6.69714   9.52813   -6.12244  0.381 37.41493  ?  402 PRO A HD2  1 
ATOM   5002 H HD3  A PRO A 1 321 ? 6.27137   11.51871  -5.43200  0.619 36.65695  ?  402 PRO A HD3  1 
ATOM   5003 H HD3  B PRO A 1 321 ? 6.18049   11.18723  -5.71088  0.381 37.41493  ?  402 PRO A HD3  1 
ATOM   5004 N N    A ARG A 1 322 ? 9.45314   9.03894   -7.43752  0.619 23.62983  ?  403 ARG A N    1 
ATOM   5005 N N    B ARG A 1 322 ? 9.92050   9.59142   -8.17208  0.381 29.44252  ?  403 ARG A N    1 
ATOM   5006 C CA   A ARG A 1 322 ? 10.14761  7.99984   -8.18003  0.619 29.28618  ?  403 ARG A CA   1 
ATOM   5007 C CA   B ARG A 1 322 ? 10.79401  8.71254   -8.94699  0.381 28.42466  ?  403 ARG A CA   1 
ATOM   5008 C C    A ARG A 1 322 ? 10.32727  8.36216   -9.64740  0.619 22.75319  ?  403 ARG A C    1 
ATOM   5009 C C    B ARG A 1 322 ? 10.77280  9.00407   -10.44395 0.381 28.61741  ?  403 ARG A C    1 
ATOM   5010 O O    A ARG A 1 322 ? 10.69522  7.49461   -10.44937 0.619 28.93682  ?  403 ARG A O    1 
ATOM   5011 O O    B ARG A 1 322 ? 11.03608  8.11409   -11.25948 0.381 26.76695  ?  403 ARG A O    1 
ATOM   5012 C CB   A ARG A 1 322 ? 9.38548   6.67985   -8.06703  0.619 37.59206  ?  403 ARG A CB   1 
ATOM   5013 C CB   B ARG A 1 322 ? 10.43464  7.24883   -8.67877  0.381 35.08597  ?  403 ARG A CB   1 
ATOM   5014 C CG   A ARG A 1 322 ? 9.27931   6.13963   -6.65050  0.619 47.37375  ?  403 ARG A CG   1 
ATOM   5015 C CG   B ARG A 1 322 ? 10.46105  6.86559   -7.21225  0.381 35.92771  ?  403 ARG A CG   1 
ATOM   5016 C CD   A ARG A 1 322 ? 10.55663  5.41170   -6.24428  0.619 52.39462  ?  403 ARG A CD   1 
ATOM   5017 C CD   B ARG A 1 322 ? 9.11127   6.31342   -6.75107  0.381 45.79204  ?  403 ARG A CD   1 
ATOM   5018 N NE   A ARG A 1 322 ? 11.52577  6.30055   -5.62348  0.619 66.85308  ?  403 ARG A NE   1 
ATOM   5019 N NE   B ARG A 1 322 ? 8.81424   5.02646   -7.36403  0.381 47.20850  ?  403 ARG A NE   1 
ATOM   5020 C CZ   A ARG A 1 322 ? 11.88944  6.23646   -4.34526  0.619 70.04320  ?  403 ARG A CZ   1 
ATOM   5021 C CZ   B ARG A 1 322 ? 7.75823   4.27427   -7.06962  0.381 37.33214  ?  403 ARG A CZ   1 
ATOM   5022 N NH1  A ARG A 1 322 ? 11.41119  5.29857   -3.53413  0.619 59.77856  ?  403 ARG A NH1  1 
ATOM   5023 N NH1  B ARG A 1 322 ? 6.85836   4.66520   -6.18134  0.381 43.94805  ?  403 ARG A NH1  1 
ATOM   5024 N NH2  A ARG A 1 322 ? 12.76045  7.12807   -3.87456  0.619 72.92832  ?  403 ARG A NH2  1 
ATOM   5025 N NH2  B ARG A 1 322 ? 7.59949   3.10667   -7.68871  0.381 36.07574  ?  403 ARG A NH2  1 
ATOM   5026 H H    A ARG A 1 322 ? 8.43731   8.98556   -7.51257  0.619 28.35580  ?  403 ARG A H    1 
ATOM   5027 H H    B ARG A 1 322 ? 8.93478   9.51674   -8.42346  0.381 35.33102  ?  403 ARG A H    1 
ATOM   5028 H HA   A ARG A 1 322 ? 11.13563  7.85925   -7.74167  0.619 35.14341  ?  403 ARG A HA   1 
ATOM   5029 H HA   B ARG A 1 322 ? 11.81799  8.89474   -8.62083  0.381 34.10959  ?  403 ARG A HA   1 
ATOM   5030 H HB2  A ARG A 1 322 ? 8.37241   6.82963   -8.44033  0.619 45.11047  ?  403 ARG A HB2  1 
ATOM   5031 H HB2  B ARG A 1 322 ? 9.42764   7.06244   -9.05202  0.381 42.10316  ?  403 ARG A HB2  1 
ATOM   5032 H HB3  A ARG A 1 322 ? 9.89757   5.92944   -8.66932  0.619 45.11047  ?  403 ARG A HB3  1 
ATOM   5033 H HB3  B ARG A 1 322 ? 11.14938  6.61249   -9.20061  0.381 42.10316  ?  403 ARG A HB3  1 
ATOM   5034 H HG2  A ARG A 1 322 ? 9.11846   6.96592   -5.95806  0.619 56.84850  ?  403 ARG A HG2  1 
ATOM   5035 H HG2  B ARG A 1 322 ? 11.21746  6.09693   -7.05379  0.381 43.11326  ?  403 ARG A HG2  1 
ATOM   5036 H HG3  A ARG A 1 322 ? 8.44839   5.43664   -6.59150  0.619 56.84850  ?  403 ARG A HG3  1 
ATOM   5037 H HG3  B ARG A 1 322 ? 10.69326  7.74621   -6.61335  0.381 43.11326  ?  403 ARG A HG3  1 
ATOM   5038 H HD2  A ARG A 1 322 ? 10.30883  4.62775   -5.52865  0.619 62.87355  ?  403 ARG A HD2  1 
ATOM   5039 H HD2  B ARG A 1 322 ? 9.12814   6.18031   -5.66936  0.381 54.95045  ?  403 ARG A HD2  1 
ATOM   5040 H HD3  A ARG A 1 322 ? 11.01647  4.97528   -7.13095  0.619 62.87355  ?  403 ARG A HD3  1 
ATOM   5041 H HD3  B ARG A 1 322 ? 8.32304   7.01337   -7.02830  0.381 54.95045  ?  403 ARG A HD3  1 
ATOM   5042 N N    A TYR A 1 323 ? 10.09316  9.61473   -10.01282 0.619 22.11311  ?  404 TYR A N    1 
ATOM   5043 N N    B TYR A 1 323 ? 10.49885  10.24608  -10.82528 0.381 25.56683  ?  404 TYR A N    1 
ATOM   5044 C CA   A TYR A 1 323 ? 10.13354  10.00747  -11.41467 0.619 20.92904  ?  404 TYR A CA   1 
ATOM   5045 C CA   B TYR A 1 323 ? 10.39904  10.58224  -12.23922 0.381 23.01927  ?  404 TYR A CA   1 
ATOM   5046 C C    A TYR A 1 323 ? 11.53503  9.89443   -11.98704 0.619 22.17239  ?  404 TYR A C    1 
ATOM   5047 C C    B TYR A 1 323 ? 11.76103  10.55565  -12.91852 0.381 22.82162  ?  404 TYR A C    1 
ATOM   5048 O O    A TYR A 1 323 ? 12.49524  10.44264  -11.43096 0.619 21.59711  ?  404 TYR A O    1 
ATOM   5049 O O    B TYR A 1 323 ? 12.77449  10.97049  -12.34460 0.381 19.04182  ?  404 TYR A O    1 
ATOM   5050 C CB   A TYR A 1 323 ? 9.68260   11.45579  -11.53440 0.619 26.28029  ?  404 TYR A CB   1 
ATOM   5051 C CB   B TYR A 1 323 ? 9.79313   11.97835  -12.38931 0.381 22.89676  ?  404 TYR A CB   1 
ATOM   5052 C CG   A TYR A 1 323 ? 9.78049   12.06136  -12.91797 0.619 19.18691  ?  404 TYR A CG   1 
ATOM   5053 C CG   B TYR A 1 323 ? 9.81657   12.55589  -13.78409 0.381 20.66533  ?  404 TYR A CG   1 
ATOM   5054 C CD1  A TYR A 1 323 ? 9.08295   11.51629  -13.98824 0.619 21.44447  ?  404 TYR A CD1  1 
ATOM   5055 C CD1  B TYR A 1 323 ? 8.96189   12.08156  -14.77251 0.381 21.96232  ?  404 TYR A CD1  1 
ATOM   5056 C CD2  A TYR A 1 323 ? 10.50902  13.21146  -13.13986 0.619 23.08255  ?  404 TYR A CD2  1 
ATOM   5057 C CD2  B TYR A 1 323 ? 10.64545  13.62377  -14.09549 0.381 24.38865  ?  404 TYR A CD2  1 
ATOM   5058 C CE1  A TYR A 1 323 ? 9.14314   12.08395  -15.24111 0.619 22.16728  ?  404 TYR A CE1  1 
ATOM   5059 C CE1  B TYR A 1 323 ? 8.95589   12.63995  -16.04718 0.381 20.27634  ?  404 TYR A CE1  1 
ATOM   5060 C CE2  A TYR A 1 323 ? 10.56617  13.79565  -14.38343 0.619 24.79675  ?  404 TYR A CE2  1 
ATOM   5061 C CE2  B TYR A 1 323 ? 10.65186  14.17896  -15.36061 0.381 26.56391  ?  404 TYR A CE2  1 
ATOM   5062 C CZ   A TYR A 1 323 ? 9.87953   13.22629  -15.43331 0.619 22.38189  ?  404 TYR A CZ   1 
ATOM   5063 C CZ   B TYR A 1 323 ? 9.80563   13.68645  -16.32930 0.381 24.17597  ?  404 TYR A CZ   1 
ATOM   5064 O OH   A TYR A 1 323 ? 9.93403   13.79643  -16.67818 0.619 27.18420  ?  404 TYR A OH   1 
ATOM   5065 O OH   B TYR A 1 323 ? 9.81952   14.24652  -17.59118 0.381 31.33853  ?  404 TYR A OH   1 
ATOM   5066 H H    A TYR A 1 323 ? 9.87452   10.37535  -9.36934  0.619 26.53573  ?  404 TYR A H    1 
ATOM   5067 H H    B TYR A 1 323 ? 10.34321  11.02938  -10.19075 0.381 30.68019  ?  404 TYR A H    1 
ATOM   5068 H HA   A TYR A 1 323 ? 9.47754   9.34694   -11.98165 0.619 25.11485  ?  404 TYR A HA   1 
ATOM   5069 H HA   B TYR A 1 323 ? 9.76266   9.84767   -12.73271 0.381 27.62312  ?  404 TYR A HA   1 
ATOM   5070 H HB2  A TYR A 1 323 ? 8.63805   11.51509  -11.22864 0.619 31.53635  ?  404 TYR A HB2  1 
ATOM   5071 H HB2  B TYR A 1 323 ? 8.75031   11.93408  -12.07518 0.381 27.47611  ?  404 TYR A HB2  1 
ATOM   5072 H HB3  A TYR A 1 323 ? 10.30005  12.06208  -10.87163 0.619 31.53635  ?  404 TYR A HB3  1 
ATOM   5073 H HB3  B TYR A 1 323 ? 10.34732  12.66249  -11.74672 0.381 27.47611  ?  404 TYR A HB3  1 
ATOM   5074 H HD1  A TYR A 1 323 ? 8.48278   10.63159  -13.83496 0.619 25.73336  ?  404 TYR A HD1  1 
ATOM   5075 H HD1  B TYR A 1 323 ? 8.29102   11.26570  -14.54732 0.381 26.35479  ?  404 TYR A HD1  1 
ATOM   5076 H HD2  A TYR A 1 323 ? 11.04630  13.66299  -12.31898 0.619 27.69906  ?  404 TYR A HD2  1 
ATOM   5077 H HD2  B TYR A 1 323 ? 11.29737  14.02837  -13.33542 0.381 29.26638  ?  404 TYR A HD2  1 
ATOM   5078 H HE1  A TYR A 1 323 ? 8.61412   11.63314  -16.06774 0.619 26.60074  ?  404 TYR A HE1  1 
ATOM   5079 H HE1  B TYR A 1 323 ? 8.29159   12.25653  -16.80752 0.381 24.33161  ?  404 TYR A HE1  1 
ATOM   5080 H HE2  A TYR A 1 323 ? 11.14523  14.69443  -14.53596 0.619 29.75610  ?  404 TYR A HE2  1 
ATOM   5081 H HE2  B TYR A 1 323 ? 11.31874  14.99708  -15.58940 0.381 31.87670  ?  404 TYR A HE2  1 
ATOM   5082 N N    A ASP A 1 324 ? 11.64727  9.21080   -13.12438 0.619 18.72468  ?  405 ASP A N    1 
ATOM   5083 N N    B ASP A 1 324 ? 11.77110  10.07145  -14.16072 0.381 21.74441  ?  405 ASP A N    1 
ATOM   5084 C CA   A ASP A 1 324 ? 12.86511  9.21021   -13.91776 0.619 16.35385  ?  405 ASP A CA   1 
ATOM   5085 C CA   B ASP A 1 324 ? 12.93825  10.13945  -15.03341 0.381 21.55891  ?  405 ASP A CA   1 
ATOM   5086 C C    A ASP A 1 324 ? 12.52189  9.86506   -15.24754 0.619 20.81227  ?  405 ASP A C    1 
ATOM   5087 C C    B ASP A 1 324 ? 12.49909  10.69403  -16.38136 0.381 22.84491  ?  405 ASP A C    1 
ATOM   5088 O O    A ASP A 1 324 ? 11.63033  9.38588   -15.96032 0.619 17.91396  ?  405 ASP A O    1 
ATOM   5089 O O    B ASP A 1 324 ? 11.59414  10.13778  -17.01858 0.381 19.72656  ?  405 ASP A O    1 
ATOM   5090 C CB   A ASP A 1 324 ? 13.35059  7.77636   -14.10741 0.619 21.77932  ?  405 ASP A CB   1 
ATOM   5091 C CB   B ASP A 1 324 ? 13.56104  8.75030   -15.20783 0.381 24.27847  ?  405 ASP A CB   1 
ATOM   5092 C CG   A ASP A 1 324 ? 14.67230  7.70599   -14.81378 0.619 20.82814  ?  405 ASP A CG   1 
ATOM   5093 C CG   B ASP A 1 324 ? 14.86795  8.79553   -15.95710 0.381 21.61556  ?  405 ASP A CG   1 
ATOM   5094 O OD1  A ASP A 1 324 ? 14.82177  8.36585   -15.86597 0.619 21.68245  ?  405 ASP A OD1  1 
ATOM   5095 O OD1  B ASP A 1 324 ? 14.96075  9.52633   -16.96544 0.381 23.98080  ?  405 ASP A OD1  1 
ATOM   5096 O OD2  A ASP A 1 324 ? 15.56720  6.97913   -14.31194 0.619 21.26516  -1 405 ASP A OD2  1 
ATOM   5097 O OD2  B ASP A 1 324 ? 15.80907  8.10177   -15.52357 0.381 27.80648  -1 405 ASP A OD2  1 
ATOM   5098 H H    A ASP A 1 324 ? 10.89927  8.64270   -13.52208 0.619 22.46962  ?  405 ASP A H    1 
ATOM   5099 H H    B ASP A 1 324 ? 10.96825  9.61780   -14.59666 0.381 26.09329  ?  405 ASP A H    1 
ATOM   5100 H HA   A ASP A 1 324 ? 13.66480  9.77938   -13.44380 0.619 19.62462  ?  405 ASP A HA   1 
ATOM   5101 H HA   B ASP A 1 324 ? 13.68401  10.81039  -14.60705 0.381 25.87070  ?  405 ASP A HA   1 
ATOM   5102 H HB2  A ASP A 1 324 ? 13.46382  7.30643   -13.13045 0.619 26.13518  ?  405 ASP A HB2  1 
ATOM   5103 H HB2  B ASP A 1 324 ? 13.74905  8.31790   -14.22508 0.381 29.13416  ?  405 ASP A HB2  1 
ATOM   5104 H HB3  A ASP A 1 324 ? 12.61969  7.22850   -14.70216 0.619 26.13518  ?  405 ASP A HB3  1 
ATOM   5105 H HB3  B ASP A 1 324 ? 12.87164  8.11820   -15.76754 0.381 29.13416  ?  405 ASP A HB3  1 
ATOM   5106 N N    A SER A 1 325 ? 13.23603  10.94219  -15.59338 0.619 20.45679  ?  406 SER A N    1 
ATOM   5107 N N    B SER A 1 325 ? 13.14317  11.78030  -16.81697 0.381 21.84465  ?  406 SER A N    1 
ATOM   5108 C CA   A SER A 1 325 ? 12.84003  11.72438  -16.76231 0.619 19.83095  ?  406 SER A CA   1 
ATOM   5109 C CA   B SER A 1 325 ? 12.74456  12.45968  -18.04403 0.381 20.23156  ?  406 SER A CA   1 
ATOM   5110 C C    A SER A 1 325 ? 13.02305  10.94714  -18.06015 0.619 20.82431  ?  406 SER A C    1 
ATOM   5111 C C    B SER A 1 325 ? 12.79297  11.54556  -19.26335 0.381 21.26968  ?  406 SER A C    1 
ATOM   5112 O O    A SER A 1 325 ? 12.44983  11.32954  -19.08908 0.619 20.53100  ?  406 SER A O    1 
ATOM   5113 O O    B SER A 1 325 ? 12.16698  11.85237  -20.28192 0.381 22.33857  ?  406 SER A O    1 
ATOM   5114 C CB   A SER A 1 325 ? 13.60235  13.04325  -16.83177 0.619 18.70521  ?  406 SER A CB   1 
ATOM   5115 C CB   B SER A 1 325 ? 13.62490  13.69476  -18.27478 0.381 27.21441  ?  406 SER A CB   1 
ATOM   5116 O OG   A SER A 1 325 ? 14.97605  12.81880  -17.05477 0.619 25.76094  ?  406 SER A OG   1 
ATOM   5117 O OG   B SER A 1 325 ? 14.60890  13.46576  -19.27732 0.381 27.53124  ?  406 SER A OG   1 
ATOM   5118 H H    A SER A 1 325 ? 14.06183  11.28385  -15.10171 0.619 24.54815  ?  406 SER A H    1 
ATOM   5119 H H    B SER A 1 325 ? 13.93875  12.20908  -16.34411 0.381 26.21358  ?  406 SER A H    1 
ATOM   5120 H HA   A SER A 1 325 ? 11.78437  11.97487  -16.65768 0.619 23.79714  ?  406 SER A HA   1 
ATOM   5121 H HA   B SER A 1 325 ? 11.71487  12.79845  -17.92971 0.381 24.27787  ?  406 SER A HA   1 
ATOM   5122 H HB2  A SER A 1 325 ? 13.20309  13.64086  -17.65126 0.619 22.44625  ?  406 SER A HB2  1 
ATOM   5123 H HB2  B SER A 1 325 ? 12.99026  14.52301  -18.58995 0.381 32.65730  ?  406 SER A HB2  1 
ATOM   5124 H HB3  A SER A 1 325 ? 13.47847  13.57454  -15.88811 0.619 22.44625  ?  406 SER A HB3  1 
ATOM   5125 H HB3  B SER A 1 325 ? 14.12829  13.94520  -17.34098 0.381 32.65730  ?  406 SER A HB3  1 
ATOM   5126 N N    A THR A 1 326 ? 13.80330  9.86011   -18.04074 0.619 18.58317  ?  407 THR A N    1 
ATOM   5127 N N    B THR A 1 326 ? 13.52806  10.43676  -19.18570 0.381 19.88138  ?  407 THR A N    1 
ATOM   5128 C CA   A THR A 1 326 ? 13.83406  8.99876   -19.21313 0.619 16.13981  ?  407 THR A CA   1 
ATOM   5129 C CA   B THR A 1 326 ? 13.56046  9.49627   -20.30124 0.381 17.42071  ?  407 THR A CA   1 
ATOM   5130 C C    A THR A 1 326 ? 12.43240  8.55250   -19.60097 0.619 15.55458  ?  407 THR A C    1 
ATOM   5131 C C    B THR A 1 326 ? 12.19010  8.86144   -20.54051 0.381 20.64612  ?  407 THR A C    1 
ATOM   5132 O O    A THR A 1 326 ? 12.17155  8.26583   -20.77001 0.619 15.87716  ?  407 THR A O    1 
ATOM   5133 O O    B THR A 1 326 ? 11.86694  8.48225   -21.67692 0.381 14.71860  ?  407 THR A O    1 
ATOM   5134 C CB   A THR A 1 326 ? 14.66753  7.74714   -18.92338 0.619 22.67426  ?  407 THR A CB   1 
ATOM   5135 C CB   B THR A 1 326 ? 14.61974  8.43593   -20.03046 0.381 21.93487  ?  407 THR A CB   1 
ATOM   5136 O OG1  A THR A 1 326 ? 15.92074  8.13884   -18.36042 0.619 23.18878  ?  407 THR A OG1  1 
ATOM   5137 O OG1  B THR A 1 326 ? 15.87159  9.07676   -19.73552 0.381 22.90351  ?  407 THR A OG1  1 
ATOM   5138 C CG2  A THR A 1 326 ? 14.87665  6.92400   -20.21168 0.619 19.27669  ?  407 THR A CG2  1 
ATOM   5139 C CG2  B THR A 1 326 ? 14.79658  7.50707   -21.23149 0.381 22.96957  ?  407 THR A CG2  1 
ATOM   5140 H H    A THR A 1 326 ? 14.39512  9.56788   -17.26309 0.619 22.29980  ?  407 THR A H    1 
ATOM   5141 H H    B THR A 1 326 ? 14.09829  10.16747  -18.38400 0.381 23.85766  ?  407 THR A H    1 
ATOM   5142 H HA   A THR A 1 326 ? 14.28770  9.55181   -20.03559 0.619 19.36778  ?  407 THR A HA   1 
ATOM   5143 H HA   B THR A 1 326 ? 13.83454  10.02074  -21.21661 0.381 20.90485  ?  407 THR A HA   1 
ATOM   5144 H HB   A THR A 1 326 ? 14.14913  7.10432   -18.21194 0.619 27.20912  ?  407 THR A HB   1 
ATOM   5145 H HB   B THR A 1 326 ? 14.30614  7.82707   -19.18250 0.381 26.32184  ?  407 THR A HB   1 
ATOM   5146 H HG21 A THR A 1 326 ? 15.56463  7.44367   -20.87855 0.619 23.13203  ?  407 THR A HG21 1 
ATOM   5147 H HG21 B THR A 1 326 ? 15.41155  7.99140   -21.99000 0.381 27.56349  ?  407 THR A HG21 1 
ATOM   5148 H HG22 A THR A 1 326 ? 15.29227  5.94669   -19.96629 0.619 23.13203  ?  407 THR A HG22 1 
ATOM   5149 H HG22 B THR A 1 326 ? 15.28252  6.58262   -20.91946 0.381 27.56349  ?  407 THR A HG22 1 
ATOM   5150 H HG23 A THR A 1 326 ? 13.92461  6.78504   -20.72394 0.619 23.13203  ?  407 THR A HG23 1 
ATOM   5151 H HG23 B THR A 1 326 ? 13.82505  7.26755   -21.66378 0.381 27.56349  ?  407 THR A HG23 1 
ATOM   5152 N N    A CYS A 1 327 ? 11.53572  8.46135   -18.63794 0.619 13.72041  ?  408 CYS A N    1 
ATOM   5153 N N    B CYS A 1 327 ? 11.35732  8.75770   -19.50307 0.381 13.96362  ?  408 CYS A N    1 
ATOM   5154 C CA   A CYS A 1 327 ? 10.19306  7.99602   -18.91462 0.619 13.08746  ?  408 CYS A CA   1 
ATOM   5155 C CA   B CYS A 1 327 ? 10.02605  8.18421   -19.67784 0.381 18.25084  ?  408 CYS A CA   1 
ATOM   5156 C C    A CYS A 1 327 ? 9.29982   9.08479   -19.49062 0.619 15.36396  ?  408 CYS A C    1 
ATOM   5157 C C    B CYS A 1 327 ? 9.02377   9.19014   -20.23422 0.381 14.94273  ?  408 CYS A C    1 
ATOM   5158 O O    A CYS A 1 327 ? 8.10650   8.83732   -19.70368 0.619 17.04293  ?  408 CYS A O    1 
ATOM   5159 O O    B CYS A 1 327 ? 7.85186   8.83952   -20.40956 0.381 16.23408  ?  408 CYS A O    1 
ATOM   5160 C CB   A CYS A 1 327 ? 9.60840   7.36669   -17.65829 0.619 15.24222  ?  408 CYS A CB   1 
ATOM   5161 C CB   B CYS A 1 327 ? 9.48406   7.60921   -18.36769 0.381 15.34077  ?  408 CYS A CB   1 
ATOM   5162 S SG   A CYS A 1 327 ? 10.61162  5.96725   -17.04885 0.619 14.68937  ?  408 CYS A SG   1 
ATOM   5163 S SG   B CYS A 1 327 ? 10.54308  6.38447   -17.54518 0.381 16.05002  ?  408 CYS A SG   1 
ATOM   5164 H H    A CYS A 1 327 ? 11.70856  8.70122   -17.66173 0.619 16.46449  ?  408 CYS A H    1 
ATOM   5165 H H    B CYS A 1 327 ? 11.57302  9.05587   -18.55177 0.381 16.75634  ?  408 CYS A H    1 
ATOM   5166 H HA   A CYS A 1 327 ? 10.21913  7.20887   -19.66815 0.619 15.70495  ?  408 CYS A HA   1 
ATOM   5167 H HA   B CYS A 1 327 ? 10.11644  7.35265   -20.37673 0.381 21.90101  ?  408 CYS A HA   1 
ATOM   5168 H HB2  A CYS A 1 327 ? 9.56248   8.11937   -16.87123 0.619 18.29066  ?  408 CYS A HB2  1 
ATOM   5169 H HB2  B CYS A 1 327 ? 9.33823   8.43222   -17.66805 0.381 18.40892  ?  408 CYS A HB2  1 
ATOM   5170 H HB3  A CYS A 1 327 ? 8.60730   6.99598   -17.87848 0.619 18.29066  ?  408 CYS A HB3  1 
ATOM   5171 H HB3  B CYS A 1 327 ? 8.53063   7.12390   -18.57634 0.381 18.40892  ?  408 CYS A HB3  1 
ATOM   5172 N N    A SER A 1 328 ? 9.85825   10.26124  -19.76794 0.619 16.30400  ?  409 SER A N    1 
ATOM   5173 N N    B SER A 1 328 ? 9.44423   10.42232  -20.49981 0.381 17.19097  ?  409 SER A N    1 
ATOM   5174 C CA   A SER A 1 328 ? 9.14181   11.35706  -20.39185 0.619 19.39953  ?  409 SER A CA   1 
ATOM   5175 C CA   B SER A 1 328 ? 8.60497   11.40574  -21.16700 0.381 18.04510  ?  409 SER A CA   1 
ATOM   5176 C C    A SER A 1 328 ? 9.59779   11.61631  -21.81462 0.619 22.53680  ?  409 SER A C    1 
ATOM   5177 C C    B SER A 1 328 ? 9.07118   11.69643  -22.58739 0.381 23.33162  ?  409 SER A C    1 
ATOM   5178 O O    A SER A 1 328 ? 9.08337   12.53645  -22.46108 0.619 21.74537  ?  409 SER A O    1 
ATOM   5179 O O    B SER A 1 328 ? 8.53746   12.60217  -23.23317 0.381 23.27895  ?  409 SER A O    1 
ATOM   5180 C CB   A SER A 1 328 ? 9.33458   12.65535  -19.59432 0.619 21.64203  ?  409 SER A CB   1 
ATOM   5181 C CB   B SER A 1 328 ? 8.55887   12.71016  -20.36699 0.381 17.95942  ?  409 SER A CB   1 
ATOM   5182 O OG   A SER A 1 328 ? 8.78536   12.52192  -18.29822 0.619 31.74208  ?  409 SER A OG   1 
ATOM   5183 O OG   B SER A 1 328 ? 7.98380   12.49219  -19.09902 0.381 23.37900  ?  409 SER A OG   1 
ATOM   5184 H H    A SER A 1 328 ? 10.83230  10.48509  -19.56414 0.619 19.56480  ?  409 SER A H    1 
ATOM   5185 H H    B SER A 1 328 ? 10.37269  10.77081  -20.26125 0.381 20.62916  ?  409 SER A H    1 
ATOM   5186 H HA   A SER A 1 328 ? 8.08199   11.10232  -20.39234 0.619 23.27943  ?  409 SER A HA   1 
ATOM   5187 H HA   B SER A 1 328 ? 7.59167   11.00680  -21.21342 0.381 21.65412  ?  409 SER A HA   1 
ATOM   5188 H HB2  A SER A 1 328 ? 10.40034  12.86800  -19.51040 0.619 25.97044  ?  409 SER A HB2  1 
ATOM   5189 H HB2  B SER A 1 328 ? 9.57423   13.08499  -20.23797 0.381 21.55131  ?  409 SER A HB2  1 
ATOM   5190 H HB3  A SER A 1 328 ? 8.83136   13.47124  -20.11316 0.619 25.97044  ?  409 SER A HB3  1 
ATOM   5191 H HB3  B SER A 1 328 ? 7.95823   13.43997  -20.90987 0.381 21.55131  ?  409 SER A HB3  1 
ATOM   5192 N N    A LEU A 1 329 ? 10.55193  10.84964  -22.32460 0.619 21.02897  ?  410 LEU A N    1 
ATOM   5193 N N    B LEU A 1 329 ? 10.04379  10.95344  -23.09426 0.381 16.64687  ?  410 LEU A N    1 
ATOM   5194 C CA   A LEU A 1 329 ? 11.06062  11.10544  -23.66389 0.619 23.37303  ?  410 LEU A CA   1 
ATOM   5195 C CA   B LEU A 1 329 ? 10.59616  11.27780  -24.38647 0.381 18.06306  ?  410 LEU A CA   1 
ATOM   5196 C C    A LEU A 1 329 ? 9.98250   10.79906  -24.70093 0.619 17.79433  ?  410 LEU A C    1 
ATOM   5197 C C    B LEU A 1 329 ? 9.58397   10.96689  -25.47758 0.381 24.01597  ?  410 LEU A C    1 
ATOM   5198 O O    A LEU A 1 329 ? 9.02585   10.07739  -24.42641 0.619 16.44653  ?  410 LEU A O    1 
ATOM   5199 O O    B LEU A 1 329 ? 8.63727   10.20026  -25.27171 0.381 16.13651  ?  410 LEU A O    1 
ATOM   5200 C CB   A LEU A 1 329 ? 12.31540  10.28296  -23.89595 0.619 19.52624  ?  410 LEU A CB   1 
ATOM   5201 C CB   B LEU A 1 329 ? 11.86108  10.47640  -24.64795 0.381 17.70540  ?  410 LEU A CB   1 
ATOM   5202 C CG   A LEU A 1 329 ? 13.46389  10.60632  -22.93422 0.619 20.03321  ?  410 LEU A CG   1 
ATOM   5203 C CG   B LEU A 1 329 ? 13.05898  10.89656  -23.80233 0.381 20.51624  ?  410 LEU A CG   1 
ATOM   5204 C CD1  A LEU A 1 329 ? 14.61882  9.62651   -23.13217 0.619 21.31178  ?  410 LEU A CD1  1 
ATOM   5205 C CD1  B LEU A 1 329 ? 14.22459  9.95564   -24.06009 0.381 24.28077  ?  410 LEU A CD1  1 
ATOM   5206 C CD2  A LEU A 1 329 ? 13.94188  12.02346  -23.14825 0.619 24.74693  ?  410 LEU A CD2  1 
ATOM   5207 C CD2  B LEU A 1 329 ? 13.45141  12.34113  -24.10416 0.381 21.56090  ?  410 LEU A CD2  1 
ATOM   5208 H H    A LEU A 1 329 ? 10.98489  10.05973  -21.84607 0.619 25.23476  ?  410 LEU A H    1 
ATOM   5209 H H    B LEU A 1 329 ? 10.45759  10.13939  -22.63984 0.381 19.97625  ?  410 LEU A H    1 
ATOM   5210 H HA   A LEU A 1 329 ? 11.33084  12.15455  -23.78415 0.619 28.04763  ?  410 LEU A HA   1 
ATOM   5211 H HA   B LEU A 1 329 ? 10.84508  12.33869  -24.41204 0.381 21.67567  ?  410 LEU A HA   1 
ATOM   5212 H HB2  A LEU A 1 329 ? 12.06771  9.22850   -23.77403 0.619 23.43149  ?  410 LEU A HB2  1 
ATOM   5213 H HB2  B LEU A 1 329 ? 11.65737  9.42716   -24.43416 0.381 21.24648  ?  410 LEU A HB2  1 
ATOM   5214 H HB3  A LEU A 1 329 ? 12.66998  10.46780  -24.90995 0.619 23.43149  ?  410 LEU A HB3  1 
ATOM   5215 H HB3  B LEU A 1 329 ? 12.13755  10.59658  -25.69543 0.381 21.24648  ?  410 LEU A HB3  1 
ATOM   5216 H HG   A LEU A 1 329 ? 13.10656  10.51187  -21.90880 0.619 24.03985  ?  410 LEU A HG   1 
ATOM   5217 H HG   B LEU A 1 329 ? 12.79640  10.84107  -22.74589 0.381 24.61949  ?  410 LEU A HG   1 
ATOM   5218 H HD11 A LEU A 1 329 ? 14.50615  9.13580   -24.09892 0.619 25.57413  ?  410 LEU A HD11 1 
ATOM   5219 H HD11 B LEU A 1 329 ? 14.79360  9.83474   -23.13829 0.381 29.13693  ?  410 LEU A HD11 1 
ATOM   5220 H HD12 A LEU A 1 329 ? 15.55963  10.17611  -23.10170 0.619 25.57413  ?  410 LEU A HD12 1 
ATOM   5221 H HD12 B LEU A 1 329 ? 13.83635  8.99085   -24.38650 0.381 29.13693  ?  410 LEU A HD12 1 
ATOM   5222 H HD13 A LEU A 1 329 ? 14.59567  8.88472   -22.33385 0.619 25.57413  ?  410 LEU A HD13 1 
ATOM   5223 H HD13 B LEU A 1 329 ? 14.86020  10.38232  -24.83600 0.381 29.13693  ?  410 LEU A HD13 1 
ATOM   5224 H HD21 A LEU A 1 329 ? 13.15382  12.71323  -22.84611 0.619 29.69631  ?  410 LEU A HD21 1 
ATOM   5225 H HD21 B LEU A 1 329 ? 13.65524  12.85695  -23.16582 0.381 25.87308  ?  410 LEU A HD21 1 
ATOM   5226 H HD22 A LEU A 1 329 ? 14.83437  12.19178  -22.54556 0.619 29.69631  ?  410 LEU A HD22 1 
ATOM   5227 H HD22 B LEU A 1 329 ? 14.34332  12.34305  -24.73073 0.381 25.87308  ?  410 LEU A HD22 1 
ATOM   5228 H HD23 A LEU A 1 329 ? 14.17427  12.16398  -24.20387 0.619 29.69631  ?  410 LEU A HD23 1 
ATOM   5229 H HD23 B LEU A 1 329 ? 12.62926  12.83050  -24.62635 0.381 25.87308  ?  410 LEU A HD23 1 
ATOM   5230 N N    A PRO A 1 330 ? 10.13689  11.32821  -25.91914 0.619 26.86762  ?  411 PRO A N    1 
ATOM   5231 N N    B PRO A 1 330 ? 9.79182   11.51845  -26.66527 0.381 23.55437  ?  411 PRO A N    1 
ATOM   5232 C CA   A PRO A 1 330 ? 9.06364   11.19577  -26.92723 0.619 25.78661  ?  411 PRO A CA   1 
ATOM   5233 C CA   B PRO A 1 330 ? 8.90082   11.20062  -27.78168 0.381 28.88299  ?  411 PRO A CA   1 
ATOM   5234 C C    A PRO A 1 330 ? 8.73268   9.77164   -27.36453 0.619 29.84116  ?  411 PRO A C    1 
ATOM   5235 C C    B PRO A 1 330 ? 8.81027   9.70611   -28.02370 0.381 23.39452  ?  411 PRO A C    1 
ATOM   5236 O O    A PRO A 1 330 ? 7.56453   9.46645   -27.64978 0.619 27.51784  ?  411 PRO A O    1 
ATOM   5237 O O    B PRO A 1 330 ? 7.87319   9.27143   -28.70584 0.381 21.24520  ?  411 PRO A O    1 
ATOM   5238 C CB   A PRO A 1 330 ? 9.58183   12.02940  -28.11922 0.619 36.42348  ?  411 PRO A CB   1 
ATOM   5239 C CB   B PRO A 1 330 ? 9.54427   11.92426  -28.97323 0.381 33.37228  ?  411 PRO A CB   1 
ATOM   5240 C CG   A PRO A 1 330 ? 10.71608  12.86751  -27.58260 0.619 26.72403  ?  411 PRO A CG   1 
ATOM   5241 C CG   B PRO A 1 330 ? 10.36667  13.01972  -28.36112 0.381 31.53792  ?  411 PRO A CG   1 
ATOM   5242 C CD   A PRO A 1 330 ? 11.29299  12.10305  -26.41103 0.619 31.85140  ?  411 PRO A CD   1 
ATOM   5243 C CD   B PRO A 1 330 ? 10.86271  12.46100  -27.05561 0.381 30.47437  ?  411 PRO A CD   1 
ATOM   5244 H HA   A PRO A 1 330 ? 8.16496   11.64459  -26.50412 0.619 30.94393  ?  411 PRO A HA   1 
ATOM   5245 H HA   B PRO A 1 330 ? 7.90608   11.61150  -27.60912 0.381 34.65959  ?  411 PRO A HA   1 
ATOM   5246 H HB2  A PRO A 1 330 ? 9.93403   11.36267  -28.90633 0.619 43.70817  ?  411 PRO A HB2  1 
ATOM   5247 H HB2  B PRO A 1 330 ? 10.17195  11.23141  -29.53365 0.381 40.04674  ?  411 PRO A HB2  1 
ATOM   5248 H HB3  A PRO A 1 330 ? 8.78016   12.66311  -28.49847 0.619 43.70817  ?  411 PRO A HB3  1 
ATOM   5249 H HB3  B PRO A 1 330 ? 8.76956   12.33343  -29.62169 0.381 40.04674  ?  411 PRO A HB3  1 
ATOM   5250 H HG2  A PRO A 1 330 ? 11.46827  13.00479  -28.35943 0.619 32.06883  ?  411 PRO A HG2  1 
ATOM   5251 H HG2  B PRO A 1 330 ? 11.19968  13.26874  -29.01853 0.381 37.84550  ?  411 PRO A HG2  1 
ATOM   5252 H HG3  A PRO A 1 330 ? 10.33369  13.83548  -27.25870 0.619 32.06883  ?  411 PRO A HG3  1 
ATOM   5253 H HG3  B PRO A 1 330 ? 9.74601   13.90039  -28.19587 0.381 37.84550  ?  411 PRO A HG3  1 
ATOM   5254 H HD2  A PRO A 1 330 ? 12.09572  11.44093  -26.73556 0.619 38.22169  ?  411 PRO A HD2  1 
ATOM   5255 H HD2  B PRO A 1 330 ? 11.80980  11.93874  -27.19114 0.381 36.56924  ?  411 PRO A HD2  1 
ATOM   5256 H HD3  A PRO A 1 330 ? 11.65946  12.78498  -25.64372 0.619 38.22169  ?  411 PRO A HD3  1 
ATOM   5257 H HD3  B PRO A 1 330 ? 10.97538  13.25058  -26.31266 0.381 36.56924  ?  411 PRO A HD3  1 
ATOM   5258 N N    . ASP A 1 331 ? 9.74910   8.89838   -27.48661 1.000 25.43140  ?  412 ASP A N    1 
ATOM   5259 C CA   . ASP A 1 331 ? 9.67236   7.45776   -27.74447 1.000 18.95209  ?  412 ASP A CA   1 
ATOM   5260 C C    . ASP A 1 331 ? 9.23121   6.62810   -26.55135 1.000 16.66169  ?  412 ASP A C    1 
ATOM   5261 O O    . ASP A 1 331 ? 9.20064   5.39171   -26.64211 1.000 19.43019  ?  412 ASP A O    1 
ATOM   5262 C CB   . ASP A 1 331 ? 10.97236  6.92774   -28.35501 1.000 21.84918  ?  412 ASP A CB   1 
ATOM   5263 C CG   . ASP A 1 331 ? 12.16142  7.12790   -27.46757 1.000 20.20995  ?  412 ASP A CG   1 
ATOM   5264 O OD1  . ASP A 1 331 ? 12.03113  7.65778   -26.36223 1.000 23.88265  ?  412 ASP A OD1  1 
ATOM   5265 O OD2  . ASP A 1 331 ? 13.28309  6.71350   -27.90011 1.000 22.64338  -1 412 ASP A OD2  1 
ATOM   5266 H H    A ASP A 1 331 ? 10.72283  9.19051   -27.40346 0.560 30.51769  ?  412 ASP A H    1 
ATOM   5267 D D    B ASP A 1 331 ? 10.52695  9.20599   -26.90289 0.440 30.51769  ?  412 ASP A D    1 
ATOM   5268 H HA   . ASP A 1 331 ? 8.90142   7.31363   -28.50143 1.000 22.74250  ?  412 ASP A HA   1 
ATOM   5269 H HB2  . ASP A 1 331 ? 10.86690  5.85851   -28.53868 1.000 26.21901  ?  412 ASP A HB2  1 
ATOM   5270 H HB3  . ASP A 1 331 ? 11.16172  7.45019   -29.29271 1.000 26.21901  ?  412 ASP A HB3  1 
ATOM   5271 N N    . ALA A 1 332 ? 8.80285   7.26318   -25.47276 1.000 19.47826  ?  413 ALA A N    1 
ATOM   5272 C CA   . ALA A 1 332 ? 8.26420   6.56148   -24.30889 1.000 16.63497  ?  413 ALA A CA   1 
ATOM   5273 C C    . ALA A 1 332 ? 6.74957   6.70286   -24.30909 1.000 18.79985  ?  413 ALA A C    1 
ATOM   5274 O O    . ALA A 1 332 ? 6.22682   7.81211   -24.49297 1.000 21.62577  ?  413 ALA A O    1 
ATOM   5275 C CB   . ALA A 1 332 ? 8.86158   7.16466   -23.03557 1.000 19.38325  ?  413 ALA A CB   1 
ATOM   5276 H H    A ALA A 1 332 ? 8.81404   8.27780   -25.36870 0.906 23.37391  ?  413 ALA A H    1 
ATOM   5277 D D    B ALA A 1 332 ? 8.81479   8.27797   -25.37043 0.094 23.37391  ?  413 ALA A D    1 
ATOM   5278 H HA   . ALA A 1 332 ? 8.50569   5.49912   -24.34313 1.000 19.96196  ?  413 ALA A HA   1 
ATOM   5279 H HB1  . ALA A 1 332 ? 9.92140   6.91448   -22.98777 1.000 23.25990  ?  413 ALA A HB1  1 
ATOM   5280 H HB2  . ALA A 1 332 ? 8.73603   8.24706   -23.06291 1.000 23.25990  ?  413 ALA A HB2  1 
ATOM   5281 H HB3  . ALA A 1 332 ? 8.34287   6.75203   -22.17025 1.000 23.25990  ?  413 ALA A HB3  1 
ATOM   5282 N N    . ALA A 1 333 ? 6.04624   5.59356   -24.08886 1.000 16.40788  ?  414 ALA A N    1 
ATOM   5283 C CA   . ALA A 1 333 ? 4.58793   5.62736   -24.02250 1.000 16.94530  ?  414 ALA A CA   1 
ATOM   5284 C C    . ALA A 1 333 ? 4.14259   6.38615   -22.77130 1.000 18.77912  ?  414 ALA A C    1 
ATOM   5285 O O    . ALA A 1 333 ? 4.64001   6.13961   -21.66623 1.000 17.79737  ?  414 ALA A O    1 
ATOM   5286 C CB   . ALA A 1 333 ? 4.03680   4.21133   -23.99032 1.000 17.95151  ?  414 ALA A CB   1 
ATOM   5287 H H    A ALA A 1 333 ? 6.45152   4.66730   -23.95399 0.782 19.68946  ?  414 ALA A H    1 
ATOM   5288 D D    B ALA A 1 333 ? 6.45022   4.66676   -23.95384 0.218 19.68946  ?  414 ALA A D    1 
ATOM   5289 H HA   . ALA A 1 333 ? 4.19225   6.13503   -24.90217 1.000 20.33436  ?  414 ALA A HA   1 
ATOM   5290 H HB1  . ALA A 1 333 ? 3.54793   3.99911   -24.94114 1.000 21.54181  ?  414 ALA A HB1  1 
ATOM   5291 H HB2  . ALA A 1 333 ? 4.85930   3.51394   -23.83145 1.000 21.54181  ?  414 ALA A HB2  1 
ATOM   5292 H HB3  . ALA A 1 333 ? 3.31713   4.12906   -23.17583 1.000 21.54181  ?  414 ALA A HB3  1 
ATOM   5293 N N    . GLN A 1 334 ? 3.17661   7.29381   -22.94234 1.000 19.29747  ?  415 GLN A N    1 
ATOM   5294 C CA   . GLN A 1 334 ? 2.71817   8.18260   -21.88331 1.000 19.30692  ?  415 GLN A CA   1 
ATOM   5295 C C    . GLN A 1 334 ? 1.21659   8.36276   -22.01083 1.000 26.36653  ?  415 GLN A C    1 
ATOM   5296 O O    . GLN A 1 334 ? 0.67231   8.24792   -23.11155 1.000 24.87375  ?  415 GLN A O    1 
ATOM   5297 C CB   . GLN A 1 334 ? 3.35402   9.57147   -22.02203 1.000 20.76064  ?  415 GLN A CB   1 
ATOM   5298 C CG   . GLN A 1 334 ? 4.81974   9.55506   -21.95475 1.000 30.99590  ?  415 GLN A CG   1 
ATOM   5299 C CD   . GLN A 1 334 ? 5.42654   10.83484  -22.42968 1.000 32.57736  ?  415 GLN A CD   1 
ATOM   5300 O OE1  . GLN A 1 334 ? 5.03673   11.92483  -21.99488 1.000 34.76449  ?  415 GLN A OE1  1 
ATOM   5301 N NE2  . GLN A 1 334 ? 6.38256   10.73111  -23.33525 1.000 31.79891  ?  415 GLN A NE2  1 
ATOM   5302 H H    A GLN A 1 334 ? 2.68586   7.43515   -23.82528 0.842 23.15697  ?  415 GLN A H    1 
ATOM   5303 D D    B GLN A 1 334 ? 2.68710   7.43353   -23.82623 0.158 23.15697  ?  415 GLN A D    1 
ATOM   5304 H HA   . GLN A 1 334 ? 2.96144   7.75032   -20.91272 1.000 23.16831  ?  415 GLN A HA   1 
ATOM   5305 H HB2  . GLN A 1 334 ? 3.06893   9.99358   -22.98569 1.000 24.91276  ?  415 GLN A HB2  1 
ATOM   5306 H HB3  . GLN A 1 334 ? 2.99000   10.20662  -21.21445 1.000 24.91276  ?  415 GLN A HB3  1 
ATOM   5307 H HG2  . GLN A 1 334 ? 5.12753   9.39751   -20.92104 1.000 37.19508  ?  415 GLN A HG2  1 
ATOM   5308 H HG3  . GLN A 1 334 ? 5.19655   8.74800   -22.58306 1.000 37.19508  ?  415 GLN A HG3  1 
ATOM   5309 N N    . PRO A 1 335 ? 0.52175   8.65284   -20.90730 1.000 22.57889  ?  416 PRO A N    1 
ATOM   5310 C CA   . PRO A 1 335 ? 1.03956   8.66367   -19.53382 1.000 18.79724  ?  416 PRO A CA   1 
ATOM   5311 C C    . PRO A 1 335 ? 1.29597   7.22855   -19.02254 1.000 21.16510  ?  416 PRO A C    1 
ATOM   5312 O O    . PRO A 1 335 ? 0.59909   6.27838   -19.38852 1.000 21.63247  ?  416 PRO A O    1 
ATOM   5313 C CB   . PRO A 1 335 ? -0.08877  9.33545   -18.75462 1.000 25.33175  ?  416 PRO A CB   1 
ATOM   5314 C CG   . PRO A 1 335 ? -1.29103  8.97569   -19.48527 1.000 26.20769  ?  416 PRO A CG   1 
ATOM   5315 C CD   . PRO A 1 335 ? -0.90655  9.02749   -20.93757 1.000 22.73697  ?  416 PRO A CD   1 
ATOM   5316 H HA   . PRO A 1 335 ? 1.94691   9.25993   -19.43742 1.000 22.55669  ?  416 PRO A HA   1 
ATOM   5317 H HB2  . PRO A 1 335 ? -0.11915  8.95237   -17.73461 1.000 30.39810  ?  416 PRO A HB2  1 
ATOM   5318 H HB3  . PRO A 1 335 ? 0.05576   10.41576  -18.74297 1.000 30.39810  ?  416 PRO A HB3  1 
ATOM   5319 H HG2  . PRO A 1 335 ? -1.60819  7.97161   -19.20361 1.000 31.44923  ?  416 PRO A HG2  1 
ATOM   5320 H HG3  . PRO A 1 335 ? -2.08369  9.69168   -19.26813 1.000 31.44923  ?  416 PRO A HG3  1 
ATOM   5321 H HD2  . PRO A 1 335 ? -1.48594  8.31187   -21.52092 1.000 27.28436  ?  416 PRO A HD2  1 
ATOM   5322 H HD3  . PRO A 1 335 ? -1.03872  10.03134  -21.34119 1.000 27.28436  ?  416 PRO A HD3  1 
ATOM   5323 N N    . ALA A 1 336 ? 2.31466   7.09409   -18.17930 1.000 20.17226  ?  417 ALA A N    1 
ATOM   5324 C CA   . ALA A 1 336 ? 2.72077   5.80884   -17.67374 1.000 17.71349  ?  417 ALA A CA   1 
ATOM   5325 C C    . ALA A 1 336 ? 2.64815   5.80574   -16.16282 1.000 18.94766  ?  417 ALA A C    1 
ATOM   5326 O O    . ALA A 1 336 ? 2.99914   6.80219   -15.53501 1.000 18.90851  ?  417 ALA A O    1 
ATOM   5327 C CB   . ALA A 1 336 ? 4.17905   5.54605   -18.08464 1.000 20.80451  ?  417 ALA A CB   1 
ATOM   5328 H H    A ALA A 1 336 ? 2.87633   7.87122   -17.83145 0.534 24.20671  ?  417 ALA A H    1 
ATOM   5329 D D    B ALA A 1 336 ? 2.87581   7.87182   -17.83196 0.466 24.20671  ?  417 ALA A D    1 
ATOM   5330 H HA   . ALA A 1 336 ? 2.07445   5.02143   -18.06150 1.000 21.25619  ?  417 ALA A HA   1 
ATOM   5331 H HB1  . ALA A 1 336 ? 4.20206   5.22617   -19.12639 1.000 24.96541  ?  417 ALA A HB1  1 
ATOM   5332 H HB2  . ALA A 1 336 ? 4.75252   6.46528   -17.96531 1.000 24.96541  ?  417 ALA A HB2  1 
ATOM   5333 H HB3  . ALA A 1 336 ? 4.59219   4.76474   -17.44670 1.000 24.96541  ?  417 ALA A HB3  1 
ATOM   5334 N N    . PRO A 1 337 ? 2.23768   4.68353   -15.55344 1.000 17.48254  ?  418 PRO A N    1 
ATOM   5335 C CA   . PRO A 1 337 ? 2.13136   4.62328   -14.09390 1.000 18.09424  ?  418 PRO A CA   1 
ATOM   5336 C C    . PRO A 1 337 ? 3.45253   4.31200   -13.42309 1.000 20.31972  ?  418 PRO A C    1 
ATOM   5337 O O    . PRO A 1 337 ? 4.51336   4.35007   -14.05510 1.000 20.44630  ?  418 PRO A O    1 
ATOM   5338 C CB   . PRO A 1 337 ? 1.09527   3.52366   -13.87642 1.000 19.41116  ?  418 PRO A CB   1 
ATOM   5339 C CG   . PRO A 1 337 ? 1.30672   2.59875   -15.04112 1.000 21.76222  ?  418 PRO A CG   1 
ATOM   5340 C CD   . PRO A 1 337 ? 1.70011   3.47299   -16.20050 1.000 17.16808  ?  418 PRO A CD   1 
ATOM   5341 H HA   . PRO A 1 337 ? 1.74976   5.56212   -13.69257 1.000 21.71308  ?  418 PRO A HA   1 
ATOM   5342 H HB2  . PRO A 1 337 ? 1.27848   3.01535   -12.92976 1.000 23.29339  ?  418 PRO A HB2  1 
ATOM   5343 H HB3  . PRO A 1 337 ? 0.09043   3.94594   -13.88446 1.000 23.29339  ?  418 PRO A HB3  1 
ATOM   5344 H HG2  . PRO A 1 337 ? 2.10053   1.88949   -14.80676 1.000 26.11466  ?  418 PRO A HG2  1 
ATOM   5345 H HG3  . PRO A 1 337 ? 0.38161   2.06464   -15.25792 1.000 26.11466  ?  418 PRO A HG3  1 
ATOM   5346 H HD2  . PRO A 1 337 ? 2.46349   2.98818   -16.80902 1.000 20.60170  ?  418 PRO A HD2  1 
ATOM   5347 H HD3  . PRO A 1 337 ? 0.83246   3.71524   -16.81418 1.000 20.60170  ?  418 PRO A HD3  1 
ATOM   5348 N N    . GLU A 1 338 ? 3.41069   4.00978   -12.12677 1.000 21.96351  ?  419 GLU A N    1 
ATOM   5349 C CA   . GLU A 1 338 ? 4.64141   3.77108   -11.38425 1.000 24.98951  ?  419 GLU A CA   1 
ATOM   5350 C C    . GLU A 1 338 ? 5.29087   2.45622   -11.81881 1.000 19.21808  ?  419 GLU A C    1 
ATOM   5351 O O    . GLU A 1 338 ? 4.61263   1.51434   -12.23877 1.000 20.04285  ?  419 GLU A O    1 
ATOM   5352 C CB   . GLU A 1 338 ? 4.36173   3.74393   -9.87698  1.000 32.89101  ?  419 GLU A CB   1 
ATOM   5353 C CG   . GLU A 1 338 ? 4.03261   5.13191   -9.29000  1.000 37.05084  ?  419 GLU A CG   1 
ATOM   5354 C CD   . GLU A 1 338 ? 5.25140   6.02859   -9.15486  1.000 29.99200  ?  419 GLU A CD   1 
ATOM   5355 O OE1  . GLU A 1 338 ? 6.36903   5.50079   -9.08063  1.000 29.61007  ?  419 GLU A OE1  1 
ATOM   5356 O OE2  . GLU A 1 338 ? 5.08377   7.27131   -9.11960  1.000 36.02015  -1 419 GLU A OE2  1 
ATOM   5357 H H    A GLU A 1 338 ? 2.55707   3.92482   -11.57494 0.694 26.35621  ?  419 GLU A H    1 
ATOM   5358 D D    B GLU A 1 338 ? 2.55784   3.92451   -11.57380 0.306 26.35621  ?  419 GLU A D    1 
ATOM   5359 H HA   . GLU A 1 338 ? 5.34472   4.57950   -11.58399 1.000 29.98742  ?  419 GLU A HA   1 
ATOM   5360 H HB2  . GLU A 1 338 ? 3.50976   3.09059   -9.68883  1.000 39.46921  ?  419 GLU A HB2  1 
ATOM   5361 H HB3  . GLU A 1 338 ? 5.24401   3.36365   -9.36212  1.000 39.46921  ?  419 GLU A HB3  1 
ATOM   5362 H HG2  . GLU A 1 338 ? 3.31946   5.63246   -9.94496  1.000 44.46101  ?  419 GLU A HG2  1 
ATOM   5363 H HG3  . GLU A 1 338 ? 3.60031   5.00247   -8.29780  1.000 44.46101  ?  419 GLU A HG3  1 
ATOM   5364 N N    . ALA A 1 339 ? 6.62252   2.41542   -11.70340 1.000 22.05135  ?  420 ALA A N    1 
ATOM   5365 C CA   . ALA A 1 339 ? 7.38344   1.22890   -12.07429 1.000 19.30096  ?  420 ALA A CA   1 
ATOM   5366 C C    . ALA A 1 339 ? 6.82164   0.01426   -11.35284 1.000 21.04428  ?  420 ALA A C    1 
ATOM   5367 O O    . ALA A 1 339 ? 6.50518   0.06933   -10.16426 1.000 22.67111  ?  420 ALA A O    1 
ATOM   5368 C CB   . ALA A 1 339 ? 8.84648   1.40375   -11.69512 1.000 24.80361  ?  420 ALA A CB   1 
ATOM   5369 H H    A ALA A 1 339 ? 7.19570   3.18521   -11.35804 0.574 26.46162  ?  420 ALA A H    1 
ATOM   5370 D D    B ALA A 1 339 ? 7.19695   3.18437   -11.35824 0.426 26.46162  ?  420 ALA A D    1 
ATOM   5371 H HA   . ALA A 1 339 ? 7.32036   1.07620   -13.15170 1.000 23.16115  ?  420 ALA A HA   1 
ATOM   5372 H HB1  . ALA A 1 339 ? 8.93073   2.21246   -10.96917 1.000 29.76433  ?  420 ALA A HB1  1 
ATOM   5373 H HB2  . ALA A 1 339 ? 9.21394   0.47421   -11.26034 1.000 29.76433  ?  420 ALA A HB2  1 
ATOM   5374 H HB3  . ALA A 1 339 ? 9.41852   1.64694   -12.59052 1.000 29.76433  ?  420 ALA A HB3  1 
ATOM   5375 N N    . GLY A 1 340 ? 6.71869   -1.09642  -12.06822 1.000 20.20898  ?  421 GLY A N    1 
ATOM   5376 C CA   . GLY A 1 340 ? 6.23731   -2.31581  -11.49818 1.000 18.37319  ?  421 GLY A CA   1 
ATOM   5377 C C    . GLY A 1 340 ? 4.76403   -2.52528  -11.63347 1.000 23.89924  ?  421 GLY A C    1 
ATOM   5378 O O    . GLY A 1 340 ? 4.30678   -3.67394  -11.61905 1.000 29.11550  ?  421 GLY A O    1 
ATOM   5379 H H    A GLY A 1 340 ? 6.96757   -1.16827  -13.05478 0.516 24.25077  ?  421 GLY A H    1 
ATOM   5380 D D    B GLY A 1 340 ? 6.96794   -1.16692  -13.05478 0.484 24.25077  ?  421 GLY A D    1 
ATOM   5381 H HA2  . GLY A 1 340 ? 6.73950   -3.15217  -11.98440 1.000 22.04782  ?  421 GLY A HA2  1 
ATOM   5382 H HA3  . GLY A 1 340 ? 6.47974   -2.32554  -10.43552 1.000 22.04782  ?  421 GLY A HA3  1 
ATOM   5383 N N    . THR A 1 341 ? 3.99805   -1.46167  -11.78113 1.000 23.44672  ?  422 THR A N    1 
ATOM   5384 C CA   . THR A 1 341 ? 2.54638   -1.61178  -11.86514 1.000 22.15474  ?  422 THR A CA   1 
ATOM   5385 C C    . THR A 1 341 ? 2.12157   -1.93517  -13.30171 1.000 19.35071  ?  422 THR A C    1 
ATOM   5386 O O    . THR A 1 341 ? 2.87389   -1.75743  -14.26572 1.000 20.05817  ?  422 THR A O    1 
ATOM   5387 C CB   . THR A 1 341 ? 1.82848   -0.37216  -11.32039 1.000 25.67703  ?  422 THR A CB   1 
ATOM   5388 O OG1  . THR A 1 341 ? 2.01827   0.73383   -12.19227 1.000 24.92604  ?  422 THR A OG1  1 
ATOM   5389 C CG2  . THR A 1 341 ? 2.34989   -0.00044  -9.93257  1.000 25.27588  ?  422 THR A CG2  1 
ATOM   5390 H H    A THR A 1 341 ? 4.33611   -0.50146  -11.84522 0.577 28.13606  ?  422 THR A H    1 
ATOM   5391 D D    B THR A 1 341 ? 4.33546   -0.50123  -11.84528 0.423 28.13606  ?  422 THR A D    1 
ATOM   5392 H HA   . THR A 1 341 ? 2.22773   -2.44706  -11.24155 1.000 26.58569  ?  422 THR A HA   1 
ATOM   5393 H HB   . THR A 1 341 ? 0.76454   -0.59670  -11.24484 1.000 30.81244  ?  422 THR A HB   1 
ATOM   5394 H HG21 . THR A 1 341 ? 1.71115   0.76167   -9.48614  1.000 30.33105  ?  422 THR A HG21 1 
ATOM   5395 H HG22 . THR A 1 341 ? 2.35476   -0.87967  -9.28833  1.000 30.33105  ?  422 THR A HG22 1 
ATOM   5396 H HG23 . THR A 1 341 ? 3.36530   0.38866   -10.00770 1.000 30.33105  ?  422 THR A HG23 1 
ATOM   5397 N N    . TRP A 1 342 ? 0.90461   -2.43628  -13.42903 1.000 19.17335  ?  423 TRP A N    1 
ATOM   5398 C CA   . TRP A 1 342 ? 0.41157   -2.87986  -14.71021 1.000 16.76194  ?  423 TRP A CA   1 
ATOM   5399 C C    . TRP A 1 342 ? 0.09596   -1.68454  -15.58877 1.000 19.69104  ?  423 TRP A C    1 
ATOM   5400 O O    . TRP A 1 342 ? -0.52669  -0.71560  -15.14373 1.000 20.42190  ?  423 TRP A O    1 
ATOM   5401 C CB   . TRP A 1 342 ? -0.83661  -3.74037  -14.53808 1.000 19.89186  ?  423 TRP A CB   1 
ATOM   5402 C CG   . TRP A 1 342 ? -1.18074  -4.45471  -15.77961 1.000 18.47075  ?  423 TRP A CG   1 
ATOM   5403 C CD1  . TRP A 1 342 ? -2.22364  -4.21491  -16.61455 1.000 17.58688  ?  423 TRP A CD1  1 
ATOM   5404 C CD2  . TRP A 1 342 ? -0.46475  -5.55358  -16.34797 1.000 17.31693  ?  423 TRP A CD2  1 
ATOM   5405 N NE1  . TRP A 1 342 ? -2.19960  -5.07362  -17.66973 1.000 19.14100  ?  423 TRP A NE1  1 
ATOM   5406 C CE2  . TRP A 1 342 ? -1.11837  -5.91873  -17.52633 1.000 17.87499  ?  423 TRP A CE2  1 
ATOM   5407 C CE3  . TRP A 1 342 ? 0.68693   -6.25006  -15.96809 1.000 16.20877  ?  423 TRP A CE3  1 
ATOM   5408 C CZ2  . TRP A 1 342 ? -0.66147  -6.96769  -18.33127 1.000 16.75613  ?  423 TRP A CZ2  1 
ATOM   5409 C CZ3  . TRP A 1 342 ? 1.12340   -7.27051  -16.76618 1.000 17.83042  ?  423 TRP A CZ3  1 
ATOM   5410 C CH2  . TRP A 1 342 ? 0.46556   -7.62923  -17.91866 1.000 16.03229  ?  423 TRP A CH2  1 
ATOM   5411 H H    A TRP A 1 342 ? 0.24025   -2.54637  -12.66293 0.804 23.00802  ?  423 TRP A H    1 
ATOM   5412 D D    B TRP A 1 342 ? 0.23931   -2.54691  -12.66382 0.196 23.00802  ?  423 TRP A D    1 
ATOM   5413 H HA   . TRP A 1 342 ? 1.17742   -3.48394  -15.19670 1.000 20.11432  ?  423 TRP A HA   1 
ATOM   5414 H HB2  . TRP A 1 342 ? -0.65921  -4.47870  -13.75609 1.000 23.87024  ?  423 TRP A HB2  1 
ATOM   5415 H HB3  . TRP A 1 342 ? -1.67777  -3.10311  -14.26523 1.000 23.87024  ?  423 TRP A HB3  1 
ATOM   5416 H HD1  . TRP A 1 342 ? -2.96932  -3.44861  -16.46242 1.000 21.10426  ?  423 TRP A HD1  1 
ATOM   5417 H HE3  . TRP A 1 342 ? 1.21895   -5.98792  -15.06552 1.000 19.45052  ?  423 TRP A HE3  1 
ATOM   5418 H HZ2  . TRP A 1 342 ? -1.17543  -7.24458  -19.23988 1.000 20.10735  ?  423 TRP A HZ2  1 
ATOM   5419 H HZ3  . TRP A 1 342 ? 2.01353   -7.81219  -16.48217 1.000 21.39650  ?  423 TRP A HZ3  1 
ATOM   5420 H HH2  . TRP A 1 342 ? 0.84457   -8.44898  -18.51092 1.000 19.23875  ?  423 TRP A HH2  1 
ATOM   5421 N N    . PHE A 1 343 ? 0.51942   -1.75543  -16.84513 1.000 17.74052  ?  424 PHE A N    1 
ATOM   5422 C CA   . PHE A 1 343 ? 0.34600   -0.70027  -17.84995 1.000 17.56423  ?  424 PHE A CA   1 
ATOM   5423 C C    . PHE A 1 343 ? -0.46103  -1.32239  -18.96934 1.000 17.36849  ?  424 PHE A C    1 
ATOM   5424 O O    . PHE A 1 343 ? 0.07251   -1.90127  -19.91298 1.000 16.73324  ?  424 PHE A O    1 
ATOM   5425 C CB   . PHE A 1 343 ? 1.75203   -0.26429  -18.30862 1.000 17.52017  ?  424 PHE A CB   1 
ATOM   5426 C CG   . PHE A 1 343 ? 1.79825   0.99736   -19.13600 1.000 16.19333  ?  424 PHE A CG   1 
ATOM   5427 C CD1  . PHE A 1 343 ? 0.63801   1.60700   -19.58051 1.000 19.96797  ?  424 PHE A CD1  1 
ATOM   5428 C CD2  . PHE A 1 343 ? 3.01507   1.56408   -19.48265 1.000 16.03756  ?  424 PHE A CD2  1 
ATOM   5429 C CE1  . PHE A 1 343 ? 0.69776   2.76550   -20.33635 1.000 19.49200  ?  424 PHE A CE1  1 
ATOM   5430 C CE2  . PHE A 1 343 ? 3.08282   2.70553   -20.25357 1.000 19.46776  ?  424 PHE A CE2  1 
ATOM   5431 C CZ   . PHE A 1 343 ? 1.90740   3.30839   -20.67002 1.000 19.24736  ?  424 PHE A CZ   1 
ATOM   5432 H H    A PHE A 1 343 ? 1.00990   -2.56780  -17.21914 1.000 21.28862  ?  424 PHE A H    1 
ATOM   5433 D D    B PHE A 1 343 ? 1.00969   -2.56920  -17.21636 0.000 21.28862  ?  424 PHE A D    1 
ATOM   5434 H HA   . PHE A 1 343 ? -0.20280  0.16388   -17.47555 1.000 21.07707  ?  424 PHE A HA   1 
ATOM   5435 H HB2  . PHE A 1 343 ? 2.36537   -0.09545  -17.42352 1.000 21.02420  ?  424 PHE A HB2  1 
ATOM   5436 H HB3  . PHE A 1 343 ? 2.18039   -1.06473  -18.91187 1.000 21.02420  ?  424 PHE A HB3  1 
ATOM   5437 H HD1  . PHE A 1 343 ? -0.32145  1.17571   -19.33592 1.000 23.96156  ?  424 PHE A HD1  1 
ATOM   5438 H HD2  . PHE A 1 343 ? 3.92958   1.10172   -19.14163 1.000 19.24507  ?  424 PHE A HD2  1 
ATOM   5439 H HE1  . PHE A 1 343 ? -0.21449  3.24209   -20.66354 1.000 23.39040  ?  424 PHE A HE1  1 
ATOM   5440 H HE2  . PHE A 1 343 ? 4.03969   3.12383   -20.52892 1.000 23.36132  ?  424 PHE A HE2  1 
ATOM   5441 H HZ   . PHE A 1 343 ? 1.94660   4.21147   -21.26105 1.000 23.09683  ?  424 PHE A HZ   1 
ATOM   5442 N N    . GLN A 1 344 ? -1.78804  -1.17839  -18.89257 1.000 17.64961  ?  425 GLN A N    1 
ATOM   5443 C CA   . GLN A 1 344 ? -2.66649  -1.96363  -19.73642 1.000 18.26135  ?  425 GLN A CA   1 
ATOM   5444 C C    . GLN A 1 344 ? -2.51773  -1.62277  -21.21141 1.000 17.18956  ?  425 GLN A C    1 
ATOM   5445 O O    . GLN A 1 344 ? -2.48131  -2.51686  -22.06323 1.000 17.70563  ?  425 GLN A O    1 
ATOM   5446 C CB   . GLN A 1 344 ? -4.11465  -1.74833  -19.27116 1.000 20.22067  ?  425 GLN A CB   1 
ATOM   5447 C CG   . GLN A 1 344 ? -5.14904  -2.36247  -20.16737 1.000 19.22110  ?  425 GLN A CG   1 
ATOM   5448 C CD   . GLN A 1 344 ? -5.14075  -3.87115  -20.11840 1.000 23.97895  ?  425 GLN A CD   1 
ATOM   5449 O OE1  . GLN A 1 344 ? -4.60319  -4.47215  -19.18992 1.000 23.39892  ?  425 GLN A OE1  1 
ATOM   5450 N NE2  . GLN A 1 344 ? -5.78019  -4.48945  -21.10883 1.000 24.21853  ?  425 GLN A NE2  1 
ATOM   5451 H H    A GLN A 1 344 ? -2.26905  -0.53498  -18.26404 0.785 21.17953  ?  425 GLN A H    1 
ATOM   5452 D D    B GLN A 1 344 ? -2.27114  -0.53571  -18.26489 0.215 21.17953  ?  425 GLN A D    1 
ATOM   5453 H HA   . GLN A 1 344 ? -2.40291  -3.01629  -19.63379 1.000 21.91362  ?  425 GLN A HA   1 
ATOM   5454 H HB2  . GLN A 1 344 ? -4.23139  -2.18972  -18.28139 1.000 24.26480  ?  425 GLN A HB2  1 
ATOM   5455 H HB3  . GLN A 1 344 ? -4.31028  -0.67694  -19.22700 1.000 24.26480  ?  425 GLN A HB3  1 
ATOM   5456 H HG2  . GLN A 1 344 ? -6.13638  -2.02036  -19.85716 1.000 23.06531  ?  425 GLN A HG2  1 
ATOM   5457 H HG3  . GLN A 1 344 ? -4.95480  -2.05731  -21.19560 1.000 23.06531  ?  425 GLN A HG3  1 
ATOM   5458 N N    . ALA A 1 345 ? -2.47772  -0.33142  -21.54056 1.000 17.58763  ?  426 ALA A N    1 
ATOM   5459 C CA   . ALA A 1 345 ? -2.36132  0.06513   -22.93729 1.000 17.57203  ?  426 ALA A CA   1 
ATOM   5460 C C    . ALA A 1 345 ? -1.08508  -0.47393  -23.54732 1.000 19.33899  ?  426 ALA A C    1 
ATOM   5461 O O    . ALA A 1 345 ? -1.04930  -0.82969  -24.73460 1.000 18.29399  ?  426 ALA A O    1 
ATOM   5462 C CB   . ALA A 1 345 ? -2.36215  1.58839   -23.06507 1.000 21.44022  ?  426 ALA A CB   1 
ATOM   5463 H H    A ALA A 1 345 ? -2.52277  0.44340   -20.87873 0.613 21.10515  ?  426 ALA A H    1 
ATOM   5464 D D    B ALA A 1 345 ? -2.52259  0.44513   -20.88075 0.387 21.10515  ?  426 ALA A D    1 
ATOM   5465 H HA   . ALA A 1 345 ? -3.22175  -0.33375  -23.47455 1.000 21.08643  ?  426 ALA A HA   1 
ATOM   5466 H HB1  . ALA A 1 345 ? -2.46892  1.85627   -24.11623 1.000 25.72826  ?  426 ALA A HB1  1 
ATOM   5467 H HB2  . ALA A 1 345 ? -3.19680  1.99213   -22.49196 1.000 25.72826  ?  426 ALA A HB2  1 
ATOM   5468 H HB3  . ALA A 1 345 ? -1.42130  1.97765   -22.67600 1.000 25.72826  ?  426 ALA A HB3  1 
ATOM   5469 N N    . TYR A 1 346 ? -0.00636  -0.51380  -22.74513 1.000 16.39733  ?  427 TYR A N    1 
ATOM   5470 C CA   . TYR A 1 346 ? 1.27675   -1.00667  -23.25272 1.000 14.88290  ?  427 TYR A CA   1 
ATOM   5471 C C    . TYR A 1 346 ? 1.21146   -2.50585  -23.51388 1.000 15.75050  ?  427 TYR A C    1 
ATOM   5472 O O    . TYR A 1 346 ? 1.71279   -2.98396  -24.52481 1.000 15.77021  ?  427 TYR A O    1 
ATOM   5473 C CB   . TYR A 1 346 ? 2.34056   -0.70274  -22.20961 1.000 14.60873  ?  427 TYR A CB   1 
ATOM   5474 C CG   . TYR A 1 346 ? 3.74337   -0.78086  -22.76877 1.000 14.73332  ?  427 TYR A CG   1 
ATOM   5475 C CD1  . TYR A 1 346 ? 4.33638   0.30678   -23.38404 1.000 13.96078  ?  427 TYR A CD1  1 
ATOM   5476 C CD2  . TYR A 1 346 ? 4.46921   -1.96736  -22.69765 1.000 13.47499  ?  427 TYR A CD2  1 
ATOM   5477 C CE1  . TYR A 1 346 ? 5.59419   0.23170   -23.92768 1.000 13.59184  ?  427 TYR A CE1  1 
ATOM   5478 C CE2  . TYR A 1 346 ? 5.73470   -2.04749  -23.24065 1.000 12.50978  ?  427 TYR A CE2  1 
ATOM   5479 C CZ   . TYR A 1 346 ? 6.30203   -0.94973  -23.82540 1.000 14.45851  ?  427 TYR A CZ   1 
ATOM   5480 O OH   . TYR A 1 346 ? 7.54880   -1.05621  -24.39903 1.000 15.04493  ?  427 TYR A OH   1 
ATOM   5481 H H    A TYR A 1 346 ? 0.00711   -0.21974  -21.76853 0.763 19.67680  ?  427 TYR A H    1 
ATOM   5482 D D    B TYR A 1 346 ? 0.00969   -0.22037  -21.76837 0.237 19.67680  ?  427 TYR A D    1 
ATOM   5483 H HA   . TYR A 1 346 ? 1.53106   -0.51151  -24.18987 1.000 17.85949  ?  427 TYR A HA   1 
ATOM   5484 H HB2  . TYR A 1 346 ? 2.18490   0.30592   -21.82690 1.000 17.53048  ?  427 TYR A HB2  1 
ATOM   5485 H HB3  . TYR A 1 346 ? 2.25935   -1.42600  -21.39819 1.000 17.53048  ?  427 TYR A HB3  1 
ATOM   5486 H HD1  . TYR A 1 346 ? 3.79520   1.23984   -23.43804 1.000 16.75293  ?  427 TYR A HD1  1 
ATOM   5487 H HD2  . TYR A 1 346 ? 4.03800   -2.83122  -22.21370 1.000 16.16999  ?  427 TYR A HD2  1 
ATOM   5488 H HE1  . TYR A 1 346 ? 6.02507   1.08567   -24.42915 1.000 16.31021  ?  427 TYR A HE1  1 
ATOM   5489 H HE2  . TYR A 1 346 ? 6.27865   -2.97977  -23.20375 1.000 15.01174  ?  427 TYR A HE2  1 
ATOM   5490 N N    . PHE A 1 347 ? 0.61072   -3.26738  -22.59828 1.000 14.78236  ?  428 PHE A N    1 
ATOM   5491 C CA   . PHE A 1 347 ? 0.39056   -4.69247  -22.81735 1.000 14.12178  ?  428 PHE A CA   1 
ATOM   5492 C C    . PHE A 1 347 ? -0.41262  -4.94437  -24.08519 1.000 15.57140  ?  428 PHE A C    1 
ATOM   5493 O O    . PHE A 1 347 ? -0.09501  -5.84285  -24.86701 1.000 17.23333  ?  428 PHE A O    1 
ATOM   5494 C CB   . PHE A 1 347 ? -0.34393  -5.28940  -21.61763 1.000 14.33320  ?  428 PHE A CB   1 
ATOM   5495 C CG   . PHE A 1 347 ? -0.66131  -6.73196  -21.76194 1.000 15.72155  ?  428 PHE A CG   1 
ATOM   5496 C CD1  . PHE A 1 347 ? 0.35530   -7.69720  -21.66619 1.000 16.71713  ?  428 PHE A CD1  1 
ATOM   5497 C CD2  . PHE A 1 347 ? -1.95365  -7.16138  -21.97867 1.000 18.39051  ?  428 PHE A CD2  1 
ATOM   5498 C CE1  . PHE A 1 347 ? 0.06208   -9.03720  -21.82342 1.000 18.66541  ?  428 PHE A CE1  1 
ATOM   5499 C CE2  . PHE A 1 347 ? -2.23819  -8.50018  -22.10878 1.000 20.95803  ?  428 PHE A CE2  1 
ATOM   5500 C CZ   . PHE A 1 347 ? -1.21306  -9.44817  -22.03070 1.000 19.01292  ?  428 PHE A CZ   1 
ATOM   5501 H H    A PHE A 1 347 ? 0.26708   -2.92844  -21.69971 0.997 17.73884  ?  428 PHE A H    1 
ATOM   5502 D D    B PHE A 1 347 ? 0.26621   -2.93096  -21.69909 0.003 17.73884  ?  428 PHE A D    1 
ATOM   5503 H HA   . PHE A 1 347 ? 1.35926   -5.18119  -22.92170 1.000 16.94614  ?  428 PHE A HA   1 
ATOM   5504 H HB2  . PHE A 1 347 ? 0.28139   -5.17431  -20.73229 1.000 17.19984  ?  428 PHE A HB2  1 
ATOM   5505 H HB3  . PHE A 1 347 ? -1.28413  -4.75487  -21.48204 1.000 17.19984  ?  428 PHE A HB3  1 
ATOM   5506 H HD1  . PHE A 1 347 ? 1.37144   -7.38930  -21.46855 1.000 20.06056  ?  428 PHE A HD1  1 
ATOM   5507 H HD2  . PHE A 1 347 ? -2.75199  -6.43724  -22.04704 1.000 22.06862  ?  428 PHE A HD2  1 
ATOM   5508 H HE1  . PHE A 1 347 ? 0.85768   -9.76631  -21.78079 1.000 22.39849  ?  428 PHE A HE1  1 
ATOM   5509 H HE2  . PHE A 1 347 ? -3.25656  -8.82073  -22.27180 1.000 25.14964  ?  428 PHE A HE2  1 
ATOM   5510 H HZ   . PHE A 1 347 ? -1.43556  -10.49987 -22.13475 1.000 22.81550  ?  428 PHE A HZ   1 
ATOM   5511 N N    . GLN A 1 348 ? -1.48677  -4.17311  -24.29548 1.000 16.87203  ?  429 GLN A N    1 
ATOM   5512 C CA   . GLN A 1 348 ? -2.31785  -4.38628  -25.46905 1.000 18.95546  ?  429 GLN A CA   1 
ATOM   5513 C C    . GLN A 1 348 ? -1.50825  -4.22712  -26.75056 1.000 15.80707  ?  429 GLN A C    1 
ATOM   5514 O O    . GLN A 1 348 ? -1.66538  -5.01154  -27.69745 1.000 18.37861  ?  429 GLN A O    1 
ATOM   5515 C CB   . GLN A 1 348 ? -3.49886  -3.42440  -25.42411 1.000 20.61035  ?  429 GLN A CB   1 
ATOM   5516 C CG   . GLN A 1 348 ? -4.43070  -3.61897  -26.59486 1.000 36.60985  ?  429 GLN A CG   1 
ATOM   5517 C CD   . GLN A 1 348 ? -5.81659  -3.09697  -26.32849 1.000 43.73133  ?  429 GLN A CD   1 
ATOM   5518 O OE1  . GLN A 1 348 ? -6.24834  -2.99204  -25.18281 1.000 38.34317  ?  429 GLN A OE1  1 
ATOM   5519 N NE2  . GLN A 1 348 ? -6.52693  -2.77195  -27.39436 1.000 55.03889  ?  429 GLN A NE2  1 
ATOM   5520 H H    A GLN A 1 348 ? -1.79349  -3.41570  -23.68503 0.620 20.24643  ?  429 GLN A H    1 
ATOM   5521 D D    B GLN A 1 348 ? -1.79554  -3.41521  -23.68667 0.380 20.24643  ?  429 GLN A D    1 
ATOM   5522 H HA   . GLN A 1 348 ? -2.71332  -5.40200  -25.46640 1.000 22.74655  ?  429 GLN A HA   1 
ATOM   5523 H HB2  . GLN A 1 348 ? -4.06331  -3.59307  -24.50703 1.000 24.73242  ?  429 GLN A HB2  1 
ATOM   5524 H HB3  . GLN A 1 348 ? -3.12746  -2.39996  -25.45020 1.000 24.73242  ?  429 GLN A HB3  1 
ATOM   5525 H HG2  . GLN A 1 348 ? -4.03097  -3.08839  -27.45904 1.000 43.93181  ?  429 GLN A HG2  1 
ATOM   5526 H HG3  . GLN A 1 348 ? -4.50798  -4.68388  -26.81421 1.000 43.93181  ?  429 GLN A HG3  1 
ATOM   5527 N N    . THR A 1 349 ? -0.58998  -3.25405  -26.78129 1.000 16.04743  ?  430 THR A N    1 
ATOM   5528 C CA   . THR A 1 349 ? 0.26600   -3.09642  -27.93380 1.000 15.12645  ?  430 THR A CA   1 
ATOM   5529 C C    . THR A 1 349 ? 1.29413   -4.21105  -28.04180 1.000 15.80492  ?  430 THR A C    1 
ATOM   5530 O O    . THR A 1 349 ? 1.59321   -4.66341  -29.14447 1.000 16.62631  ?  430 THR A O    1 
ATOM   5531 C CB   . THR A 1 349 ? 0.90693   -1.73328  -27.88534 1.000 15.48567  ?  430 THR A CB   1 
ATOM   5532 O OG1  . THR A 1 349 ? -0.15755  -0.74964  -27.94575 1.000 21.59855  ?  430 THR A OG1  1 
ATOM   5533 C CG2  . THR A 1 349 ? 1.82997   -1.53022  -29.03761 1.000 20.45519  ?  430 THR A CG2  1 
ATOM   5534 H H    A THR A 1 349 ? -0.42711  -2.57940  -26.03382 0.597 19.25691  ?  430 THR A H    1 
ATOM   5535 D D    B THR A 1 349 ? -0.42518  -2.57827  -26.03526 0.403 19.25691  ?  430 THR A D    1 
ATOM   5536 H HA   . THR A 1 349 ? -0.33303  -3.15472  -28.84257 1.000 18.15174  ?  430 THR A HA   1 
ATOM   5537 H HB   . THR A 1 349 ? 1.49530   -1.62174  -26.97458 1.000 18.58281  ?  430 THR A HB   1 
ATOM   5538 H HG21 . THR A 1 349 ? 1.37773   -1.91804  -29.95040 1.000 24.54623  ?  430 THR A HG21 1 
ATOM   5539 H HG22 . THR A 1 349 ? 2.03505   -0.46769  -29.16825 1.000 24.54623  ?  430 THR A HG22 1 
ATOM   5540 H HG23 . THR A 1 349 ? 2.76984   -2.05254  -28.85893 1.000 24.54623  ?  430 THR A HG23 1 
ATOM   5541 N N    . LEU A 1 350 ? 1.85532   -4.66435  -26.92247 1.000 13.87508  ?  431 LEU A N    1 
ATOM   5542 C CA   . LEU A 1 350 ? 2.78796   -5.78780  -26.98299 1.000 14.22281  ?  431 LEU A CA   1 
ATOM   5543 C C    . LEU A 1 350 ? 2.14874   -6.99220  -27.65300 1.000 14.10996  ?  431 LEU A C    1 
ATOM   5544 O O    . LEU A 1 350 ? 2.79489   -7.69207  -28.42780 1.000 14.57069  ?  431 LEU A O    1 
ATOM   5545 C CB   . LEU A 1 350 ? 3.23649   -6.18218  -25.58551 1.000 15.14517  ?  431 LEU A CB   1 
ATOM   5546 C CG   . LEU A 1 350 ? 4.27429   -5.29131  -24.89137 1.000 12.90407  ?  431 LEU A CG   1 
ATOM   5547 C CD1  . LEU A 1 350 ? 4.41105   -5.73027  -23.44796 1.000 15.11228  ?  431 LEU A CD1  1 
ATOM   5548 C CD2  . LEU A 1 350 ? 5.59930   -5.40274  -25.61410 1.000 14.45364  ?  431 LEU A CD2  1 
ATOM   5549 H H    A LEU A 1 350 ? 1.69147   -4.28902  -25.98829 0.925 16.65009  ?  431 LEU A H    1 
ATOM   5550 D D    B LEU A 1 350 ? 1.69313   -4.29081  -25.98729 0.075 16.65009  ?  431 LEU A D    1 
ATOM   5551 H HA   . LEU A 1 350 ? 3.65941   -5.47326  -27.55722 1.000 17.06737  ?  431 LEU A HA   1 
ATOM   5552 H HB2  . LEU A 1 350 ? 2.35467   -6.19527  -24.94493 1.000 18.17420  ?  431 LEU A HB2  1 
ATOM   5553 H HB3  . LEU A 1 350 ? 3.66898   -7.18094  -25.64492 1.000 18.17420  ?  431 LEU A HB3  1 
ATOM   5554 H HG   . LEU A 1 350 ? 3.96392   -4.24662  -24.91128 1.000 15.48489  ?  431 LEU A HG   1 
ATOM   5555 H HD11 . LEU A 1 350 ? 3.41894   -5.79476  -23.00113 1.000 18.13473  ?  431 LEU A HD11 1 
ATOM   5556 H HD12 . LEU A 1 350 ? 4.89626   -6.70587  -23.41818 1.000 18.13473  ?  431 LEU A HD12 1 
ATOM   5557 H HD13 . LEU A 1 350 ? 5.01408   -4.99866  -22.91017 1.000 18.13473  ?  431 LEU A HD13 1 
ATOM   5558 H HD21 . LEU A 1 350 ? 6.09853   -6.31957  -25.30059 1.000 17.34437  ?  431 LEU A HD21 1 
ATOM   5559 H HD22 . LEU A 1 350 ? 5.41655   -5.42769  -26.68839 1.000 17.34437  ?  431 LEU A HD22 1 
ATOM   5560 H HD23 . LEU A 1 350 ? 6.21489   -4.53934  -25.36174 1.000 17.34437  ?  431 LEU A HD23 1 
ATOM   5561 N N    . VAL A 1 351 ? 0.87290   -7.25897  -27.33578 1.000 14.99055  ?  432 VAL A N    1 
ATOM   5562 C CA   . VAL A 1 351 ? 0.14910   -8.35649  -27.95052 1.000 15.78813  ?  432 VAL A CA   1 
ATOM   5563 C C    . VAL A 1 351 ? -0.07405  -8.07736  -29.42972 1.000 17.59485  ?  432 VAL A C    1 
ATOM   5564 O O    . VAL A 1 351 ? 0.16975   -8.92812  -30.27901 1.000 18.37432  ?  432 VAL A O    1 
ATOM   5565 C CB   . VAL A 1 351 ? -1.18367  -8.55075  -27.19367 1.000 18.07810  ?  432 VAL A CB   1 
ATOM   5566 C CG1  . VAL A 1 351 ? -2.06739  -9.53953  -27.92771 1.000 30.36165  ?  432 VAL A CG1  1 
ATOM   5567 C CG2  . VAL A 1 351 ? -0.95443  -9.02645  -25.77601 1.000 16.33598  ?  432 VAL A CG2  1 
ATOM   5568 H H    A VAL A 1 351 ? 0.32404   -6.72962  -26.65832 0.982 17.98866  ?  432 VAL A H    1 
ATOM   5569 D D    B VAL A 1 351 ? 0.32233   -6.73093  -26.65869 0.018 17.98866  ?  432 VAL A D    1 
ATOM   5570 H HA   . VAL A 1 351 ? 0.73314   -9.27418  -27.88089 1.000 18.94576  ?  432 VAL A HA   1 
ATOM   5571 H HB   . VAL A 1 351 ? -1.68622  -7.58463  -27.14720 1.000 21.69372  ?  432 VAL A HB   1 
ATOM   5572 H HG11 . VAL A 1 351 ? -2.17097  -9.22094  -28.96495 1.000 36.43398  ?  432 VAL A HG11 1 
ATOM   5573 H HG12 . VAL A 1 351 ? -1.60635  -10.52636 -27.88625 1.000 36.43398  ?  432 VAL A HG12 1 
ATOM   5574 H HG13 . VAL A 1 351 ? -3.04555  -9.56579  -27.44749 1.000 36.43398  ?  432 VAL A HG13 1 
ATOM   5575 H HG21 . VAL A 1 351 ? -0.13008  -8.46136  -25.34101 1.000 19.60317  ?  432 VAL A HG21 1 
ATOM   5576 H HG22 . VAL A 1 351 ? -1.86300  -8.86445  -25.19605 1.000 19.60317  ?  432 VAL A HG22 1 
ATOM   5577 H HG23 . VAL A 1 351 ? -0.70889  -10.08829 -25.79333 1.000 19.60317  ?  432 VAL A HG23 1 
ATOM   5578 N N    A SER A 1 352 ? -0.54647  -6.87708  -29.75053 0.444 16.82446  ?  433 SER A N    1 
ATOM   5579 N N    B SER A 1 352 ? -0.55418  -6.87862  -29.75433 0.556 16.86982  ?  433 SER A N    1 
ATOM   5580 C CA   A SER A 1 352 ? -0.93377  -6.57591  -31.11924 0.444 17.95435  ?  433 SER A CA   1 
ATOM   5581 C CA   B SER A 1 352 ? -0.91580  -6.58065  -31.13212 0.556 17.95797  ?  433 SER A CA   1 
ATOM   5582 C C    A SER A 1 352 ? 0.26938   -6.52243  -32.05115 0.444 21.12490  ?  433 SER A C    1 
ATOM   5583 C C    B SER A 1 352 ? 0.30247   -6.61117  -32.03671 0.556 21.21354  ?  433 SER A C    1 
ATOM   5584 O O    A SER A 1 352 ? 0.15915   -6.88553  -33.22753 0.444 22.24127  ?  433 SER A O    1 
ATOM   5585 O O    B SER A 1 352 ? 0.23929   -7.10411  -33.17158 0.556 21.74830  ?  433 SER A O    1 
ATOM   5586 C CB   A SER A 1 352 ? -1.67864  -5.24454  -31.15552 0.444 21.82198  ?  433 SER A CB   1 
ATOM   5587 C CB   B SER A 1 352 ? -1.56537  -5.20390  -31.21415 0.556 21.77742  ?  433 SER A CB   1 
ATOM   5588 O OG   A SER A 1 352 ? -2.15533  -4.97742  -32.46158 0.444 31.02132  ?  433 SER A OG   1 
ATOM   5589 O OG   B SER A 1 352 ? -2.81435  -5.19453  -30.55921 0.556 30.71353  ?  433 SER A OG   1 
ATOM   5590 H H    A SER A 1 352 ? -0.67070  -6.10495  -29.09571 0.612 20.18936  ?  433 SER A H    1 
ATOM   5591 D D    B SER A 1 352 ? -0.70169  -6.10876  -29.10168 0.388 20.24378  ?  433 SER A D    1 
ATOM   5592 H HA   A SER A 1 352 ? -1.59948  -7.36120  -31.47735 0.444 21.54522  ?  433 SER A HA   1 
ATOM   5593 H HA   B SER A 1 352 ? -1.62928  -7.33172  -31.47116 0.556 21.54957  ?  433 SER A HA   1 
ATOM   5594 H HB2  A SER A 1 352 ? -2.52488  -5.29108  -30.47009 0.444 26.18637  ?  433 SER A HB2  1 
ATOM   5595 H HB2  B SER A 1 352 ? -0.91033  -4.47435  -30.73796 0.556 26.13290  ?  433 SER A HB2  1 
ATOM   5596 H HB3  A SER A 1 352 ? -0.99857  -4.44762  -30.85465 0.444 26.18637  ?  433 SER A HB3  1 
ATOM   5597 H HB3  B SER A 1 352 ? -1.71321  -4.94399  -32.26234 0.556 26.13290  ?  433 SER A HB3  1 
ATOM   5598 N N    . ALA A 1 353 ? 1.42101   -6.09133  -31.54969 1.000 16.49420  ?  434 ALA A N    1 
ATOM   5599 C CA   . ALA A 1 353 ? 2.64017   -5.97240  -32.33930 1.000 15.54376  ?  434 ALA A CA   1 
ATOM   5600 C C    . ALA A 1 353 ? 3.58424   -7.15685  -32.15741 1.000 17.44329  ?  434 ALA A C    1 
ATOM   5601 O O    . ALA A 1 353 ? 4.72027   -7.09589  -32.63728 1.000 18.85016  ?  434 ALA A O    1 
ATOM   5602 C CB   . ALA A 1 353 ? 3.37683   -4.65762  -32.01740 1.000 15.61601  ?  434 ALA A CB   1 
ATOM   5603 H H    A ALA A 1 353 ? 1.54340   -5.81051  -30.57678 0.918 19.79304  ?  434 ALA A H    1 
ATOM   5604 D D    B ALA A 1 353 ? 1.51456   -5.73873  -30.59716 0.082 19.79304  ?  434 ALA A D    1 
ATOM   5605 H HA   . ALA A 1 353 ? 2.35434   -5.93461  -33.39048 1.000 18.65251  ?  434 ALA A HA   1 
ATOM   5606 H HB1  . ALA A 1 353 ? 2.68015   -3.82582  -32.12157 1.000 18.73921  ?  434 ALA A HB1  1 
ATOM   5607 H HB2  . ALA A 1 353 ? 3.75219   -4.70228  -30.99505 1.000 18.73921  ?  434 ALA A HB2  1 
ATOM   5608 H HB3  . ALA A 1 353 ? 4.20705   -4.53648  -32.71322 1.000 18.73921  ?  434 ALA A HB3  1 
ATOM   5609 N N    . ALA A 1 354 ? 3.12535   -8.23334  -31.50868 1.000 15.78762  ?  435 ALA A N    1 
ATOM   5610 C CA   . ALA A 1 354 ? 3.97168   -9.39690  -31.30974 1.000 16.98984  ?  435 ALA A CA   1 
ATOM   5611 C C    . ALA A 1 354 ? 4.53560   -9.85325  -32.64745 1.000 17.54575  ?  435 ALA A C    1 
ATOM   5612 O O    . ALA A 1 354 ? 3.81032   -9.96714  -33.64215 1.000 20.26973  ?  435 ALA A O    1 
ATOM   5613 C CB   . ALA A 1 354 ? 3.18444   -10.52641 -30.64893 1.000 18.86069  ?  435 ALA A CB   1 
ATOM   5614 H H    A ALA A 1 354 ? 2.18691   -8.32093  -31.11873 0.992 18.94515  ?  435 ALA A H    1 
ATOM   5615 D D    B ALA A 1 354 ? 2.18718   -8.32205  -31.11834 0.008 18.94515  ?  435 ALA A D    1 
ATOM   5616 H HA   . ALA A 1 354 ? 4.79540   -9.14147  -30.64315 1.000 20.38781  ?  435 ALA A HA   1 
ATOM   5617 H HB1  . ALA A 1 354 ? 3.02012   -10.27823 -29.60036 1.000 22.63282  ?  435 ALA A HB1  1 
ATOM   5618 H HB2  . ALA A 1 354 ? 2.22756   -10.63767 -31.15893 1.000 22.63282  ?  435 ALA A HB2  1 
ATOM   5619 H HB3  . ALA A 1 354 ? 3.75685   -11.45074 -30.72683 1.000 22.63282  ?  435 ALA A HB3  1 
ATOM   5620 N N    . ASN A 1 355 ? 5.83957   -10.15014 -32.66655 1.000 17.52138  ?  436 ASN A N    1 
ATOM   5621 C CA   . ASN A 1 355 ? 6.50574   -10.75859 -33.81643 1.000 19.62693  ?  436 ASN A CA   1 
ATOM   5622 C C    . ASN A 1 355 ? 7.46334   -11.83090 -33.32306 1.000 22.15679  ?  436 ASN A C    1 
ATOM   5623 O O    . ASN A 1 355 ? 8.47067   -11.48980 -32.69775 1.000 22.00165  ?  436 ASN A O    1 
ATOM   5624 C CB   . ASN A 1 355 ? 7.25319   -9.66886  -34.56814 1.000 22.32755  ?  436 ASN A CB   1 
ATOM   5625 C CG   . ASN A 1 355 ? 7.94296   -10.17813 -35.80787 1.000 29.62648  ?  436 ASN A CG   1 
ATOM   5626 O OD1  . ASN A 1 355 ? 7.54900   -11.18910 -36.38903 1.000 29.94729  ?  436 ASN A OD1  1 
ATOM   5627 N ND2  . ASN A 1 355 ? 8.98661   -9.48400  -36.20900 1.000 41.51675  ?  436 ASN A ND2  1 
ATOM   5628 H H    A ASN A 1 355 ? 6.47080   -9.97677  -31.88432 0.698 21.02565  ?  436 ASN A H    1 
ATOM   5629 D D    B ASN A 1 355 ? 6.47066   -9.97670  -31.88422 0.302 21.02565  ?  436 ASN A D    1 
ATOM   5630 H HA   . ASN A 1 355 ? 5.79095   -11.23139 -34.48995 1.000 23.55232  ?  436 ASN A HA   1 
ATOM   5631 H HB2  . ASN A 1 355 ? 6.54521   -8.89711  -34.87024 1.000 26.79306  ?  436 ASN A HB2  1 
ATOM   5632 H HB3  . ASN A 1 355 ? 8.01213   -9.24241  -33.91222 1.000 26.79306  ?  436 ASN A HB3  1 
ATOM   5633 N N    . PRO A 1 356 ? 7.21627   -13.12679 -33.59802 1.000 20.48047  ?  437 PRO A N    1 
ATOM   5634 C CA   . PRO A 1 356 ? 6.11534   -13.66928 -34.39183 1.000 20.46159  ?  437 PRO A CA   1 
ATOM   5635 C C    . PRO A 1 356 ? 4.78816   -13.37380 -33.75723 1.000 25.68363  ?  437 PRO A C    1 
ATOM   5636 O O    . PRO A 1 356 ? 4.72286   -13.09178 -32.57185 1.000 21.55092  ?  437 PRO A O    1 
ATOM   5637 C CB   . PRO A 1 356 ? 6.36191   -15.19484 -34.35838 1.000 29.96822  ?  437 PRO A CB   1 
ATOM   5638 C CG   . PRO A 1 356 ? 7.76826   -15.36491 -34.00944 1.000 32.01883  ?  437 PRO A CG   1 
ATOM   5639 C CD   . PRO A 1 356 ? 8.10341   -14.19745 -33.10819 1.000 32.54038  ?  437 PRO A CD   1 
ATOM   5640 H HA   . PRO A 1 356 ? 6.15560   -13.30332 -35.41777 1.000 24.55391  ?  437 PRO A HA   1 
ATOM   5641 H HB2  . PRO A 1 356 ? 5.71919   -15.65394 -33.60722 1.000 35.96186  ?  437 PRO A HB2  1 
ATOM   5642 H HB3  . PRO A 1 356 ? 6.15282   -15.62183 -35.33923 1.000 35.96186  ?  437 PRO A HB3  1 
ATOM   5643 H HG2  . PRO A 1 356 ? 7.90741   -16.31102 -33.48635 1.000 38.42259  ?  437 PRO A HG2  1 
ATOM   5644 H HG3  . PRO A 1 356 ? 8.37812   -15.34509 -34.91264 1.000 38.42259  ?  437 PRO A HG3  1 
ATOM   5645 H HD2  . PRO A 1 356 ? 7.88577   -14.43587 -32.06709 1.000 39.04846  ?  437 PRO A HD2  1 
ATOM   5646 H HD3  . PRO A 1 356 ? 9.15027   -13.91307 -33.21453 1.000 39.04846  ?  437 PRO A HD3  1 
ATOM   5647 N N    . PRO A 1 357 ? 3.70985   -13.44005 -34.52938 1.000 23.79304  ?  438 PRO A N    1 
ATOM   5648 C CA   . PRO A 1 357 ? 2.37930   -13.24024 -33.94860 1.000 22.16501  ?  438 PRO A CA   1 
ATOM   5649 C C    . PRO A 1 357 ? 2.03557   -14.31076 -32.93627 1.000 19.57638  ?  438 PRO A C    1 
ATOM   5650 O O    . PRO A 1 357 ? 2.45783   -15.46572 -33.04248 1.000 23.93869  ?  438 PRO A O    1 
ATOM   5651 C CB   . PRO A 1 357 ? 1.44206   -13.33207 -35.17267 1.000 23.69076  ?  438 PRO A CB   1 
ATOM   5652 C CG   . PRO A 1 357 ? 2.27462   -12.91363 -36.29649 1.000 30.18279  ?  438 PRO A CG   1 
ATOM   5653 C CD   . PRO A 1 357 ? 3.67102   -13.45744 -36.01002 1.000 33.78658  ?  438 PRO A CD   1 
ATOM   5654 H HA   . PRO A 1 357 ? 2.31348   -12.25652 -33.48378 1.000 26.59801  ?  438 PRO A HA   1 
ATOM   5655 H HB2  . PRO A 1 357 ? 1.09423   -14.35701 -35.30154 1.000 28.42891  ?  438 PRO A HB2  1 
ATOM   5656 H HB3  . PRO A 1 357 ? 0.59124   -12.66311 -35.04348 1.000 28.42891  ?  438 PRO A HB3  1 
ATOM   5657 H HG2  . PRO A 1 357 ? 1.87991   -13.33307 -37.22189 1.000 36.21934  ?  438 PRO A HG2  1 
ATOM   5658 H HG3  . PRO A 1 357 ? 2.28962   -11.82541 -36.35701 1.000 36.21934  ?  438 PRO A HG3  1 
ATOM   5659 H HD2  . PRO A 1 357 ? 3.78531   -14.47083 -36.39483 1.000 40.54390  ?  438 PRO A HD2  1 
ATOM   5660 H HD3  . PRO A 1 357 ? 4.43973   -12.80971 -36.43150 1.000 40.54390  ?  438 PRO A HD3  1 
ATOM   5661 N N    . LEU A 1 358 ? 1.27066   -13.90465 -31.93550 1.000 21.10680  ?  439 LEU A N    1 
ATOM   5662 C CA   . LEU A 1 358 ? 0.70288   -14.83853 -30.99276 1.000 31.40198  ?  439 LEU A CA   1 
ATOM   5663 C C    . LEU A 1 358 ? -0.44939  -15.63888 -31.59003 1.000 38.39411  ?  439 LEU A C    1 
ATOM   5664 O O    . LEU A 1 358 ? -1.02840  -15.29271 -32.61366 1.000 35.13416  ?  439 LEU A O    1 
ATOM   5665 C CB   . LEU A 1 358 ? 0.16653   -14.06819 -29.77692 1.000 25.20238  ?  439 LEU A CB   1 
ATOM   5666 C CG   . LEU A 1 358 ? 1.25179   -13.39287 -28.93815 1.000 22.94237  ?  439 LEU A CG   1 
ATOM   5667 C CD1  . LEU A 1 358 ? 0.57624   -12.43135 -27.98433 1.000 27.25441  ?  439 LEU A CD1  1 
ATOM   5668 C CD2  . LEU A 1 358 ? 2.09367   -14.39006 -28.18461 1.000 31.33159  ?  439 LEU A CD2  1 
ATOM   5669 O OXT  . LEU A 1 358 ? -0.87855  -16.63930 -31.01130 1.000 39.33582  ?  439 LEU A OXT  1 
ATOM   5670 H H    C LEU A 1 358 ? 1.02796   -12.93058 -31.75472 0.677 25.32816  ?  439 LEU A H    1 
ATOM   5671 D D    D LEU A 1 358 ? 1.02796   -12.93058 -31.75472 0.323 25.32816  ?  439 LEU A D    1 
ATOM   5672 H HA   . LEU A 1 358 ? 1.48335   -15.53865 -30.69475 1.000 37.68237  ?  439 LEU A HA   1 
ATOM   5673 H HB2  . LEU A 1 358 ? -0.51262  -13.29155 -30.12861 1.000 30.24286  ?  439 LEU A HB2  1 
ATOM   5674 H HB3  . LEU A 1 358 ? -0.36691  -14.76522 -29.13063 1.000 30.24286  ?  439 LEU A HB3  1 
ATOM   5675 H HG   . LEU A 1 358 ? 1.93870   -12.85604 -29.59241 1.000 27.53084  ?  439 LEU A HG   1 
ATOM   5676 H HD11 . LEU A 1 358 ? 0.51019   -12.89537 -27.00024 1.000 32.70529  ?  439 LEU A HD11 1 
ATOM   5677 H HD12 . LEU A 1 358 ? 1.16635   -11.51682 -27.92520 1.000 32.70529  ?  439 LEU A HD12 1 
ATOM   5678 H HD13 . LEU A 1 358 ? -0.42301  -12.20552 -28.35661 1.000 32.70529  ?  439 LEU A HD13 1 
ATOM   5679 H HD21 . LEU A 1 358 ? 2.50026   -15.11553 -28.88922 1.000 37.59791  ?  439 LEU A HD21 1 
ATOM   5680 H HD22 . LEU A 1 358 ? 2.90570   -13.86258 -27.68413 1.000 37.59791  ?  439 LEU A HD22 1 
ATOM   5681 H HD23 . LEU A 1 358 ? 1.46981   -14.89652 -27.44814 1.000 37.59791  ?  439 LEU A HD23 1 
HETATM 5682 O O    . HOH B 2 .   ? 18.17951  10.22512  -25.26899 1.000 35.72698  ?  501 HOH A O    1 
HETATM 5683 O O    . HOH B 2 .   ? 14.17907  12.34946  -13.09457 1.000 36.63045  ?  502 HOH A O    1 
HETATM 5684 O O    . HOH B 2 .   ? -6.76769  -2.76642  -23.11425 1.000 32.91030  ?  503 HOH A O    1 
HETATM 5685 O O    . HOH B 2 .   ? 12.42051  14.05510  -20.77984 1.000 38.01390  ?  504 HOH A O    1 
HETATM 5686 O O    . HOH B 2 .   ? 12.87423  11.26554  -8.94860  1.000 44.51756  ?  505 HOH A O    1 
HETATM 5687 O O    . HOH B 2 .   ? 24.085    -28.451   -24.461   1.000 44.27985  ?  506 HOH A O    1 
HETATM 5688 O O    . HOH B 2 .   ? 34.611    9.729     -18.507   1.000 30.14746  ?  507 HOH A O    1 
HETATM 5689 O O    . HOH B 2 .   ? 17.92441  6.93453   -15.64425 1.000 36.39342  ?  508 HOH A O    1 
HETATM 5690 O O    . HOH B 2 .   ? 21.47269  -30.77817 -16.09497 1.000 34.19092  ?  509 HOH A O    1 
HETATM 5691 O O    . HOH B 2 .   ? 27.59527  4.08486   -19.29498 1.000 34.99939  ?  510 HOH A O    1 
HETATM 5692 O O    . HOH B 2 .   ? 22.63336  -8.47115  -39.87829 1.000 49.85889  ?  511 HOH A O    1 
HETATM 5693 O O    . HOH B 2 .   ? -0.86273  9.73286   -24.46473 1.000 35.26801  ?  512 HOH A O    1 
HETATM 5694 O O    . HOH B 2 .   ? 13.97967  -1.16872  -19.59929 1.000 25.45608  ?  513 HOH A O    1 
HETATM 5695 O O    . HOH B 2 .   ? 10.45811  5.14595   -11.41452 1.000 38.82726  ?  514 HOH A O    1 
HETATM 5696 O O    . HOH B 2 .   ? 31.85865  -7.96367  -34.16691 1.000 40.27157  ?  515 HOH A O    1 
HETATM 5697 O O    . HOH B 2 .   ? -1.07230  0.62631   -13.02185 1.000 38.61336  ?  516 HOH A O    1 
HETATM 5698 O O    . HOH B 2 .   ? 10.09429  7.32133   -13.91216 1.000 33.94871  ?  517 HOH A O    1 
HETATM 5699 O O    . HOH B 2 .   ? 25.063    9.082     -38.646   1.000 33.66098  ?  518 HOH A O    1 
HETATM 5700 O O    . HOH B 2 .   ? 26.80245  4.97144   -3.54805  1.000 26.83418  ?  519 HOH A O    1 
HETATM 5701 O O    . HOH B 2 .   ? 18.76309  1.03848   -3.22774  1.000 27.85753  ?  520 HOH A O    1 
HETATM 5702 O O    . HOH B 2 .   ? 26.90275  -17.99155 -32.11023 1.000 23.18862  ?  521 HOH A O    1 
HETATM 5703 O O    . HOH B 2 .   ? 21.04410  0.99994   -22.23677 1.000 47.02271  ?  522 HOH A O    1 
HETATM 5704 O O    . HOH B 2 .   ? 10.73109  -5.54578  1.08105   1.000 40.22396  ?  523 HOH A O    1 
HETATM 5705 O O    . HOH B 2 .   ? 22.48397  -29.77546 -11.07481 1.000 23.49533  ?  524 HOH A O    1 
HETATM 5706 O O    . HOH B 2 .   ? 36.24451  -10.67219 -29.44452 1.000 31.15613  ?  525 HOH A O    1 
HETATM 5707 O O    . HOH B 2 .   ? 8.76894   4.48927   -30.41464 1.000 27.26079  ?  526 HOH A O    1 
HETATM 5708 O O    . HOH B 2 .   ? 6.30548   -13.45193 -11.19608 1.000 31.48391  ?  527 HOH A O    1 
HETATM 5709 O O    . HOH B 2 .   ? 5.19265   -26.20561 -15.16437 1.000 21.97845  ?  528 HOH A O    1 
HETATM 5710 O O    . HOH B 2 .   ? 17.77045  -27.21385 -27.93029 1.000 40.85393  ?  529 HOH A O    1 
HETATM 5711 O O    . HOH B 2 .   ? 15.17102  0.80455   -9.00386  1.000 35.38993  ?  530 HOH A O    1 
HETATM 5712 O O    . HOH B 2 .   ? 20.97669  -7.27153  -19.42771 1.000 13.04082  ?  531 HOH A O    1 
HETATM 5713 O O    . HOH B 2 .   ? 23.075    1.361     11.693    1.000 24.55648  ?  532 HOH A O    1 
HETATM 5714 O O    . HOH B 2 .   ? 17.12325  -2.16919  -31.65434 1.000 17.58837  ?  533 HOH A O    1 
HETATM 5715 O O    . HOH B 2 .   ? 1.21761   -9.39423  -34.09137 1.000 27.81090  ?  534 HOH A O    1 
HETATM 5716 O O    . HOH B 2 .   ? 32.70065  -15.92329 -31.69544 1.000 35.69313  ?  535 HOH A O    1 
HETATM 5717 O O    . HOH B 2 .   ? 1.95420   -14.68517 -6.25681  1.000 42.97078  ?  536 HOH A O    1 
HETATM 5718 O O    . HOH B 2 .   ? 25.835    0.985     7.592     1.000 40.24674  ?  537 HOH A O    1 
HETATM 5719 O O    . HOH B 2 .   ? 5.00877   9.19406   -26.41882 1.000 41.85483  ?  538 HOH A O    1 
HETATM 5720 O O    . HOH B 2 .   ? 30.98291  0.54688   -1.58223  1.000 22.52173  ?  539 HOH A O    1 
HETATM 5721 O O    . HOH B 2 .   ? 23.10052  -18.15591 3.00058   1.000 34.76771  ?  540 HOH A O    1 
HETATM 5722 O O    . HOH B 2 .   ? 23.09379  -10.40635 -37.08738 1.000 28.46251  ?  541 HOH A O    1 
HETATM 5723 O O    . HOH B 2 .   ? 6.06748   -0.77812  -20.27929 1.000 22.62882  ?  542 HOH A O    1 
HETATM 5724 O O    . HOH B 2 .   ? 24.76148  -23.78648 -24.98355 1.000 28.58442  ?  543 HOH A O    1 
HETATM 5725 O O    . HOH B 2 .   ? 1.94007   -16.96171 -2.94009  1.000 31.40421  ?  544 HOH A O    1 
HETATM 5726 O O    . HOH B 2 .   ? 4.64469   15.61393  -16.12831 1.000 45.21493  ?  545 HOH A O    1 
HETATM 5727 O O    . HOH B 2 .   ? 7.98157   4.88163   -11.13072 1.000 29.89206  ?  546 HOH A O    1 
HETATM 5728 O O    . HOH B 2 .   ? 20.76301  4.56522   -1.91884  1.000 39.34889  ?  547 HOH A O    1 
HETATM 5729 O O    . HOH B 2 .   ? 13.09613  -26.31553 -19.88136 1.000 35.87552  ?  548 HOH A O    1 
HETATM 5730 O O    . HOH B 2 .   ? 21.14287  -4.46221  -9.24034  1.000 13.51728  ?  549 HOH A O    1 
HETATM 5731 O O    . HOH B 2 .   ? 12.59977  -1.52982  -16.73733 1.000 42.57373  ?  550 HOH A O    1 
HETATM 5732 O O    . HOH B 2 .   ? 23.41284  8.65618   -9.95256  1.000 35.24562  ?  551 HOH A O    1 
HETATM 5733 O O    . HOH B 2 .   ? 13.81144  -21.77569 -21.81306 1.000 21.87916  ?  552 HOH A O    1 
HETATM 5734 O O    . HOH B 2 .   ? 14.23537  -30.85864 -22.65221 1.000 35.25776  ?  553 HOH A O    1 
HETATM 5735 O O    . HOH B 2 .   ? 15.34804  3.26460   -34.29083 1.000 25.27720  ?  554 HOH A O    1 
HETATM 5736 O O    . HOH B 2 .   ? 8.40987   -7.76258  -11.66009 1.000 35.01777  ?  555 HOH A O    1 
HETATM 5737 O O    . HOH B 2 .   ? 34.68746  -14.91665 -1.88261  1.000 19.58020  ?  556 HOH A O    1 
HETATM 5738 O O    . HOH B 2 .   ? 27.50374  -20.65060 -32.36466 1.000 33.61292  ?  557 HOH A O    1 
HETATM 5739 O O    . HOH B 2 .   ? 32.16552  -21.44669 -4.70573  1.000 39.11857  ?  558 HOH A O    1 
HETATM 5740 O O    . HOH B 2 .   ? 29.27337  -2.20804  2.04449   1.000 25.08830  ?  559 HOH A O    1 
HETATM 5741 O O    . HOH B 2 .   ? 19.63200  -0.26636  3.94889   1.000 22.79339  ?  560 HOH A O    1 
HETATM 5742 O O    . HOH B 2 .   ? 6.86119   6.23910   -20.11256 1.000 20.31278  ?  561 HOH A O    1 
HETATM 5743 O O    . HOH B 2 .   ? 37.98747  -4.34468  -25.71713 1.000 20.47807  ?  562 HOH A O    1 
HETATM 5744 O O    . HOH B 2 .   ? 14.92932  -13.69255 -31.57420 1.000 32.61031  ?  563 HOH A O    1 
HETATM 5745 O O    . HOH B 2 .   ? 18.26892  1.24162   -23.85532 1.000 35.14969  ?  564 HOH A O    1 
HETATM 5746 O O    . HOH B 2 .   ? 32.66618  -12.67488 -6.81384  1.000 17.60328  ?  565 HOH A O    1 
HETATM 5747 O O    . HOH B 2 .   ? 31.20718  -11.08792 -0.21009  1.000 17.39110  ?  566 HOH A O    1 
HETATM 5748 O O    . HOH B 2 .   ? 8.80420   -32.32075 -7.81906  1.000 22.51864  ?  567 HOH A O    1 
HETATM 5749 O O    . HOH B 2 .   ? 11.16106  -11.45509 -33.12259 1.000 28.06521  ?  568 HOH A O    1 
HETATM 5750 O O    . HOH B 2 .   ? 0.04794   -11.00728 -32.03483 1.000 27.87934  ?  569 HOH A O    1 
HETATM 5751 O O    . HOH B 2 .   ? 5.03429   -6.29303  -35.22319 1.000 37.83983  ?  570 HOH A O    1 
HETATM 5752 O O    . HOH B 2 .   ? 30.83649  -21.53018 -24.01762 1.000 34.59164  ?  571 HOH A O    1 
HETATM 5753 O O    . HOH B 2 .   ? 9.83591   -4.45365  -29.61618 1.000 14.64893  ?  572 HOH A O    1 
HETATM 5754 O O    . HOH B 2 .   ? 30.29937  -10.74634 2.33232   1.000 17.21722  ?  573 HOH A O    1 
HETATM 5755 O O    . HOH B 2 .   ? 23.53979  -9.91616  7.52757   1.000 37.07761  ?  574 HOH A O    1 
HETATM 5756 O O    . HOH B 2 .   ? 18.82948  -1.15292  8.23671   1.000 41.96416  ?  575 HOH A O    1 
HETATM 5757 O O    . HOH B 2 .   ? 7.72659   -10.03177 -21.68872 1.000 26.78989  ?  576 HOH A O    1 
HETATM 5758 O O    . HOH B 2 .   ? 25.72989  -7.85317  -13.16766 1.000 22.60964  ?  577 HOH A O    1 
HETATM 5759 O O    . HOH B 2 .   ? 8.48875   -5.32609  -13.87178 1.000 25.07688  ?  578 HOH A O    1 
HETATM 5760 O O    . HOH B 2 .   ? 25.24159  4.18536   -31.57106 1.000 18.39629  ?  579 HOH A O    1 
HETATM 5761 O O    . HOH B 2 .   ? 2.10846   11.43382  -16.86552 1.000 38.06552  ?  580 HOH A O    1 
HETATM 5762 O O    . HOH B 2 .   ? 29.407    -26.485   -27.441   1.000 40.55063  ?  581 HOH A O    1 
HETATM 5763 O O    . HOH B 2 .   ? 22.20381  -1.99479  -9.17558  1.000 14.75979  ?  582 HOH A O    1 
HETATM 5764 O O    . HOH B 2 .   ? 5.07333   -16.55269 -17.04035 1.000 15.74949  ?  583 HOH A O    1 
HETATM 5765 O O    . HOH B 2 .   ? 0.99700   1.74981   -27.88361 1.000 41.74451  ?  584 HOH A O    1 
HETATM 5766 O O    . HOH B 2 .   ? 39.39524  -1.59873  -24.60535 1.000 28.22266  ?  585 HOH A O    1 
HETATM 5767 O O    . HOH B 2 .   ? 8.39163   -21.97444 2.72212   1.000 34.82120  ?  586 HOH A O    1 
HETATM 5768 O O    . HOH B 2 .   ? 19.49430  -30.07376 -17.71685 1.000 21.29735  ?  587 HOH A O    1 
HETATM 5769 O O    . HOH B 2 .   ? 7.33228   -18.65946 -15.55301 1.000 19.32800  ?  588 HOH A O    1 
HETATM 5770 O O    . HOH B 2 .   ? 12.61073  -11.33979 -30.65752 1.000 19.01601  ?  589 HOH A O    1 
HETATM 5771 O O    . HOH B 2 .   ? 18.68509  -25.70882 -8.75718  1.000 17.01983  ?  590 HOH A O    1 
HETATM 5772 O O    . HOH B 2 .   ? 17.29993  -8.13668  4.81568   1.000 27.49298  ?  591 HOH A O    1 
HETATM 5773 O O    . HOH B 2 .   ? 16.01044  -26.03587 -5.06291  1.000 27.55836  ?  592 HOH A O    1 
HETATM 5774 O O    . HOH B 2 .   ? 12.28740  -0.18581  -14.15418 1.000 42.74582  ?  593 HOH A O    1 
HETATM 5775 O O    . HOH B 2 .   ? 20.30891  5.85597   -8.50701  1.000 32.34651  ?  594 HOH A O    1 
HETATM 5776 O O    . HOH B 2 .   ? 7.63294   -10.28970 -8.10848  1.000 30.71380  ?  595 HOH A O    1 
HETATM 5777 O O    . HOH B 2 .   ? 17.70766  -4.30737  -34.79186 1.000 21.26452  ?  596 HOH A O    1 
HETATM 5778 O O    . HOH B 2 .   ? 19.74916  3.51166   -5.05064  1.000 30.16126  ?  597 HOH A O    1 
HETATM 5779 O O    . HOH B 2 .   ? 14.78810  0.24138   -31.36485 1.000 15.97711  ?  598 HOH A O    1 
HETATM 5780 O O    . HOH B 2 .   ? 6.93249   -12.87787 -14.11298 1.000 17.53341  ?  599 HOH A O    1 
HETATM 5781 O O    . HOH B 2 .   ? 21.31524  -4.40878  -17.03479 1.000 20.96266  ?  600 HOH A O    1 
HETATM 5782 O O    . HOH B 2 .   ? 5.80900   -10.83390 -12.68782 1.000 20.41117  ?  601 HOH A O    1 
HETATM 5783 O O    . HOH B 2 .   ? 20.73942  -13.81723 7.96798   1.000 37.55990  ?  602 HOH A O    1 
HETATM 5784 O O    . HOH B 2 .   ? 35.56373  3.35273   -6.56528  1.000 42.65918  ?  603 HOH A O    1 
HETATM 5785 O O    . HOH B 2 .   ? 9.52843   -19.97427 -12.99843 1.000 19.76687  ?  604 HOH A O    1 
HETATM 5786 O O    . HOH B 2 .   ? 18.86056  -28.98206 -10.19761 1.000 28.49181  ?  605 HOH A O    1 
HETATM 5787 O O    . HOH B 2 .   ? 25.36118  -25.03496 -21.31025 1.000 26.09498  ?  606 HOH A O    1 
HETATM 5788 O O    . HOH B 2 .   ? 20.34228  -3.45675  -34.81587 1.000 16.80853  ?  607 HOH A O    1 
HETATM 5789 O O    . HOH B 2 .   ? 20.32827  -19.34682 4.91330   1.000 33.06436  ?  608 HOH A O    1 
HETATM 5790 O O    . HOH B 2 .   ? 13.49176  -7.99666  -24.90337 1.000 14.30327  ?  609 HOH A O    1 
HETATM 5791 O O    . HOH B 2 .   ? 11.53092  -17.19025 -19.92635 1.000 12.54317  ?  610 HOH A O    1 
HETATM 5792 O O    . HOH B 2 .   ? 3.43687   -21.63628 -24.18560 1.000 39.41992  ?  611 HOH A O    1 
HETATM 5793 O O    . HOH B 2 .   ? 28.37895  1.51144   -37.65994 1.000 35.90227  ?  612 HOH A O    1 
HETATM 5794 O O    . HOH B 2 .   ? 29.19133  -5.72147  -37.92495 1.000 32.66158  ?  613 HOH A O    1 
HETATM 5795 O O    . HOH B 2 .   ? 8.78901   -17.33354 -12.80348 1.000 24.03274  ?  614 HOH A O    1 
HETATM 5796 O O    . HOH B 2 .   ? 15.499    10.283    -27.464   1.000 36.22793  ?  615 HOH A O    1 
HETATM 5797 O O    . HOH B 2 .   ? 3.12883   8.62839   -10.62218 1.000 43.67745  ?  616 HOH A O    1 
HETATM 5798 O O    . HOH B 2 .   ? -1.51757  5.33906   -17.78539 1.000 46.18863  ?  617 HOH A O    1 
HETATM 5799 O O    . HOH B 2 .   ? 12.00782  -2.58697  -6.52111  1.000 31.09195  ?  618 HOH A O    1 
HETATM 5800 O O    . HOH B 2 .   ? 11.31428  -8.80742  -21.77409 1.000 12.79887  ?  619 HOH A O    1 
HETATM 5801 O O    . HOH B 2 .   ? 13.69982  -2.76087  -3.17220  1.000 24.32599  ?  620 HOH A O    1 
HETATM 5802 O O    . HOH B 2 .   ? 29.03053  11.97981  -10.54358 1.000 33.63248  ?  621 HOH A O    1 
HETATM 5803 O O    . HOH B 2 .   ? 2.27473   -20.66585 -5.61936  1.000 41.13522  ?  622 HOH A O    1 
HETATM 5804 O O    . HOH B 2 .   ? 32.515    -5.037    1.958     1.000 25.39527  ?  623 HOH A O    1 
HETATM 5805 O O    . HOH B 2 .   ? 34.35311  -5.87304  -2.43985  1.000 30.74449  ?  624 HOH A O    1 
HETATM 5806 O O    . HOH B 2 .   ? 33.03989  1.04758   -32.20939 1.000 26.24418  ?  625 HOH A O    1 
HETATM 5807 O O    . HOH B 2 .   ? 12.54245  -19.63790 -20.29818 1.000 16.39734  ?  626 HOH A O    1 
HETATM 5808 O O    . HOH B 2 .   ? 10.41348  -19.58501 -29.79502 1.000 22.96409  ?  627 HOH A O    1 
HETATM 5809 O O    . HOH B 2 .   ? 1.81431   -22.24719 -12.20895 1.000 39.55097  ?  628 HOH A O    1 
HETATM 5810 O O    . HOH B 2 .   ? 21.41763  -28.23262 -8.91450  1.000 23.65965  ?  629 HOH A O    1 
HETATM 5811 O O    . HOH B 2 .   ? 16.64156  -3.43654  -37.18173 1.000 21.45964  ?  630 HOH A O    1 
HETATM 5812 O O    . HOH B 2 .   ? 31.87497  -21.88228 -13.98384 1.000 20.90853  ?  631 HOH A O    1 
HETATM 5813 O O    . HOH B 2 .   ? 12.30788  -6.17724  -22.09291 1.000 11.94918  ?  632 HOH A O    1 
HETATM 5814 O O    . HOH B 2 .   ? 17.92634  -2.12573  -2.63660  1.000 15.64047  ?  633 HOH A O    1 
HETATM 5815 O O    . HOH B 2 .   ? 4.12417   -1.70195  -26.49357 1.000 18.87424  ?  634 HOH A O    1 
HETATM 5816 O O    . HOH B 2 .   ? 2.48927   7.86395   -25.64905 1.000 34.39366  ?  635 HOH A O    1 
HETATM 5817 O O    . HOH B 2 .   ? 39.25895  -19.16360 -7.57693  1.000 35.47884  ?  636 HOH A O    1 
HETATM 5818 O O    . HOH B 2 .   ? 6.29993   -3.52786  -19.93192 1.000 15.36001  ?  637 HOH A O    1 
HETATM 5819 O O    . HOH B 2 .   ? 18.55875  -4.52269  -17.09169 1.000 23.81362  ?  638 HOH A O    1 
HETATM 5820 O O    . HOH B 2 .   ? 1.07449   4.41885   -10.52809 1.000 35.37656  ?  639 HOH A O    1 
HETATM 5821 O O    . HOH B 2 .   ? -2.91447  0.03713   -16.56083 1.000 32.71447  ?  640 HOH A O    1 
HETATM 5822 O O    . HOH B 2 .   ? 28.39030  -8.23595  -39.23842 1.000 48.06778  ?  641 HOH A O    1 
HETATM 5823 O O    . HOH B 2 .   ? 24.93948  -5.51839  -14.65910 1.000 12.73399  ?  642 HOH A O    1 
HETATM 5824 O O    . HOH B 2 .   ? 1.03097   -27.51013 -7.45114  1.000 30.63939  ?  643 HOH A O    1 
HETATM 5825 O O    . HOH B 2 .   ? 30.28881  -21.73621 -2.73529  1.000 25.11792  ?  644 HOH A O    1 
HETATM 5826 O O    . HOH B 2 .   ? 18.32357  -25.56311 -6.12687  1.000 32.92661  ?  645 HOH A O    1 
HETATM 5827 O O    . HOH B 2 .   ? 23.751    -24.024   -27.516   1.000 28.71636  ?  646 HOH A O    1 
HETATM 5828 O O    . HOH B 2 .   ? 24.16756  4.93900   0.65233   1.000 27.80558  ?  647 HOH A O    1 
HETATM 5829 O O    . HOH B 2 .   ? 10.35342  -30.76585 -9.66112  1.000 19.93297  ?  648 HOH A O    1 
HETATM 5830 O O    . HOH B 2 .   ? 21.74449  6.02337   -30.45997 1.000 21.56350  ?  649 HOH A O    1 
HETATM 5831 O O    . HOH B 2 .   ? 16.14258  -24.01394 5.16819   1.000 35.71586  ?  650 HOH A O    1 
HETATM 5832 O O    . HOH B 2 .   ? 24.25736  4.09678   -17.95668 1.000 49.20917  ?  651 HOH A O    1 
HETATM 5833 O O    . HOH B 2 .   ? 16.47807  15.54276  -17.88681 1.000 48.35404  ?  652 HOH A O    1 
HETATM 5834 O O    . HOH B 2 .   ? -0.67355  -2.91848  -11.06391 1.000 34.91688  ?  653 HOH A O    1 
HETATM 5835 O O    . HOH B 2 .   ? 10.62701  -33.20118 -16.67919 1.000 30.93182  ?  654 HOH A O    1 
HETATM 5836 O O    . HOH B 2 .   ? 30.70792  -10.46706 -33.31834 1.000 22.63219  ?  655 HOH A O    1 
HETATM 5837 O O    . HOH B 2 .   ? -3.30444  -6.75384  -14.95142 1.000 26.92808  ?  656 HOH A O    1 
HETATM 5838 O O    . HOH B 2 .   ? 17.14462  -1.10171  -40.08672 1.000 29.14814  ?  657 HOH A O    1 
HETATM 5839 O O    . HOH B 2 .   ? 12.45047  -2.71068  3.51919   1.000 41.49646  ?  658 HOH A O    1 
HETATM 5840 O O    . HOH B 2 .   ? 26.37373  10.32330  -8.44456  1.000 28.29603  ?  659 HOH A O    1 
HETATM 5841 O O    . HOH B 2 .   ? 29.36338  -24.58010 -15.94422 1.000 30.44592  ?  660 HOH A O    1 
HETATM 5842 O O    . HOH B 2 .   ? 3.42246   -24.16087 -14.31926 1.000 22.73456  ?  661 HOH A O    1 
HETATM 5843 O O    . HOH B 2 .   ? -4.87581  -16.15088 -19.19853 1.000 39.88258  ?  662 HOH A O    1 
HETATM 5844 O O    . HOH B 2 .   ? 8.13069   -10.44623 -11.02859 1.000 19.87884  ?  663 HOH A O    1 
HETATM 5845 O O    . HOH B 2 .   ? 12.67296  6.00590   -22.95520 1.000 23.40671  ?  664 HOH A O    1 
HETATM 5846 O O    . HOH B 2 .   ? 9.90278   -11.18476 3.95615   1.000 32.36912  ?  665 HOH A O    1 
HETATM 5847 O O    . HOH B 2 .   ? 33.73361  1.65762   -3.78670  1.000 23.51034  ?  666 HOH A O    1 
HETATM 5848 O O    . HOH B 2 .   ? 8.04033   -20.83933 -24.76443 1.000 30.63046  ?  667 HOH A O    1 
HETATM 5849 O O    . HOH B 2 .   ? 2.56043   -16.91138 -16.29600 1.000 20.04968  ?  668 HOH A O    1 
HETATM 5850 O O    . HOH B 2 .   ? 12.97445  -25.03354 -25.63592 1.000 32.34123  ?  669 HOH A O    1 
HETATM 5851 O O    . HOH B 2 .   ? 8.83236   -17.56784 -31.07698 1.000 25.03475  ?  670 HOH A O    1 
HETATM 5852 O O    . HOH B 2 .   ? 37.40517  -3.83133  -15.79320 1.000 33.84765  ?  671 HOH A O    1 
HETATM 5853 O O    . HOH B 2 .   ? 14.64587  4.53843   -12.95275 1.000 35.28818  ?  672 HOH A O    1 
HETATM 5854 O O    . HOH B 2 .   ? 13.69367  -2.26406  -30.60228 1.000 16.46057  ?  673 HOH A O    1 
HETATM 5855 O O    . HOH B 2 .   ? 31.81461  7.23978   -16.28864 1.000 27.27549  ?  674 HOH A O    1 
HETATM 5856 O O    . HOH B 2 .   ? -0.33254  -30.28734 -8.42162  1.000 42.37453  ?  675 HOH A O    1 
HETATM 5857 O O    . HOH B 2 .   ? 8.41459   -25.86813 -20.06781 1.000 30.92005  ?  676 HOH A O    1 
HETATM 5858 O O    . HOH B 2 .   ? 25.81797  -0.64984  -36.58934 1.000 24.02216  ?  677 HOH A O    1 
HETATM 5859 O O    . HOH B 2 .   ? 27.39770  -27.01055 -15.20207 1.000 33.81985  ?  678 HOH A O    1 
HETATM 5860 O O    . HOH B 2 .   ? -3.02414  1.93965   -19.72375 1.000 27.91912  ?  679 HOH A O    1 
HETATM 5861 O O    . HOH B 2 .   ? 30.11714  -22.18977 -17.12826 1.000 36.79064  ?  680 HOH A O    1 
HETATM 5862 O O    . HOH B 2 .   ? -0.41706  -20.02735 -16.36488 1.000 32.04701  ?  681 HOH A O    1 
HETATM 5863 O O    . HOH B 2 .   ? 1.24603   9.14107   -15.03358 1.000 34.63790  ?  682 HOH A O    1 
HETATM 5864 O O    . HOH B 2 .   ? -3.11781  -0.52048  -26.84060 1.000 33.38791  ?  683 HOH A O    1 
HETATM 5865 O O    . HOH B 2 .   ? -8.99370  -13.88743 -18.59200 1.000 40.65045  ?  684 HOH A O    1 
HETATM 5866 O O    . HOH B 2 .   ? 22.47438  2.37972   -13.21777 1.000 22.02430  ?  685 HOH A O    1 
HETATM 5867 O O    . HOH B 2 .   ? 6.00720   -24.13763 -19.23610 1.000 32.59891  ?  686 HOH A O    1 
HETATM 5868 O O    . HOH B 2 .   ? 21.843    -30.670   -20.535   1.000 24.65880  ?  687 HOH A O    1 
HETATM 5869 O O    . HOH B 2 .   ? 26.76601  -1.28996  3.48934   1.000 23.73390  ?  688 HOH A O    1 
HETATM 5870 O O    . HOH B 2 .   ? 3.46634   1.02384   -26.79962 1.000 24.03486  ?  689 HOH A O    1 
HETATM 5871 O O    . HOH B 2 .   ? 33.77765  -6.56072  -31.78372 1.000 29.43073  ?  690 HOH A O    1 
HETATM 5872 O O    . HOH B 2 .   ? 8.04905   -6.55331  -36.17664 1.000 40.25270  ?  691 HOH A O    1 
HETATM 5873 O O    . HOH B 2 .   ? 14.02822  -9.22381  -32.98450 1.000 39.03257  ?  692 HOH A O    1 
HETATM 5874 O O    . HOH B 2 .   ? 13.24718  -17.43507 4.42427   1.000 27.01590  ?  693 HOH A O    1 
HETATM 5875 O O    . HOH B 2 .   ? 32.86331  -9.88044  -6.81247  1.000 32.68708  ?  694 HOH A O    1 
HETATM 5876 O O    . HOH B 2 .   ? 12.01163  3.91493   -13.16039 1.000 34.67300  ?  695 HOH A O    1 
HETATM 5877 O O    . HOH B 2 .   ? 33.78185  3.76042   -16.12740 1.000 26.40879  ?  696 HOH A O    1 
HETATM 5878 O O    . HOH B 2 .   ? 16.59666  -28.38734 -24.23953 1.000 46.75284  ?  697 HOH A O    1 
HETATM 5879 O O    . HOH B 2 .   ? 10.50011  -16.26138 4.19755   1.000 32.87890  ?  698 HOH A O    1 
HETATM 5880 O O    . HOH B 2 .   ? 24.23665  -12.45407 6.95873   1.000 35.36235  ?  699 HOH A O    1 
HETATM 5881 O O    . HOH B 2 .   ? 29.36661  -23.61013 -25.23812 1.000 44.10274  ?  700 HOH A O    1 
HETATM 5882 O O    . HOH B 2 .   ? 24.47739  -20.91292 1.38483   1.000 38.35705  ?  701 HOH A O    1 
HETATM 5883 O O    . HOH B 2 .   ? -6.44098  -18.39863 -25.19613 1.000 39.62505  ?  702 HOH A O    1 
HETATM 5884 O O    . HOH B 2 .   ? 26.35729  -3.29103  6.16957   1.000 25.91333  ?  703 HOH A O    1 
HETATM 5885 O O    . HOH B 2 .   ? 19.35193  -4.38261  -31.66968 1.000 18.71257  ?  704 HOH A O    1 
HETATM 5886 O O    . HOH B 2 .   ? 23.85291  7.09864   -2.66614  1.000 58.40880  ?  705 HOH A O    1 
HETATM 5887 O O    . HOH B 2 .   ? 10.65438  -5.21561  -36.44908 1.000 32.82893  ?  706 HOH A O    1 
HETATM 5888 O O    . HOH B 2 .   ? 28.57745  6.46137   -32.45876 1.000 27.15840  ?  707 HOH A O    1 
HETATM 5889 O O    . HOH B 2 .   ? 34.95415  1.11145   -20.52467 1.000 33.82711  ?  708 HOH A O    1 
HETATM 5890 O O    . HOH B 2 .   ? -9.45327  -3.13960  -25.87790 1.000 37.63019  ?  709 HOH A O    1 
HETATM 5891 O O    . HOH B 2 .   ? 22.31492  6.82316   -26.17123 1.000 39.11974  ?  710 HOH A O    1 
HETATM 5892 O O    . HOH B 2 .   ? 33.96622  -10.53004 -1.45116  1.000 30.33907  ?  711 HOH A O    1 
HETATM 5893 O O    . HOH B 2 .   ? -1.36570  -10.68044 -10.16805 1.000 39.25437  ?  712 HOH A O    1 
HETATM 5894 O O    . HOH B 2 .   ? 1.68439   -33.63114 -5.58701  1.000 35.06127  ?  713 HOH A O    1 
HETATM 5895 O O    . HOH B 2 .   ? 23.22855  3.35860   9.54658   1.000 34.56413  ?  714 HOH A O    1 
HETATM 5896 O O    . HOH B 2 .   ? 20.05810  -4.88121  -20.61642 1.000 24.24435  ?  715 HOH A O    1 
HETATM 5897 O O    . HOH B 2 .   ? -2.51074  -7.84570  -34.48234 1.000 43.47690  ?  716 HOH A O    1 
HETATM 5898 O O    . HOH B 2 .   ? 29.19958  -12.16597 -35.10101 1.000 34.66190  ?  717 HOH A O    1 
HETATM 5899 O O    . HOH B 2 .   ? 34.34280  0.85617   -29.57917 1.000 24.27062  ?  718 HOH A O    1 
HETATM 5900 O O    . HOH B 2 .   ? 12.74331  1.31385   -40.37987 1.000 44.10179  ?  719 HOH A O    1 
HETATM 5901 O O    . HOH B 2 .   ? 15.89285  -11.28589 -33.11652 1.000 24.21924  ?  720 HOH A O    1 
HETATM 5902 O O    . HOH B 2 .   ? 18.31466  -2.42822  -19.90984 1.000 40.47417  ?  721 HOH A O    1 
HETATM 5903 O O    . HOH B 2 .   ? 33.52106  9.45203   -9.61662  1.000 44.66419  ?  722 HOH A O    1 
HETATM 5904 O O    . HOH B 2 .   ? 18.53977  8.10079   -22.71699 1.000 45.05894  ?  723 HOH A O    1 
HETATM 5905 O O    . HOH B 2 .   ? 22.05019  -26.48598 -25.63515 1.000 36.19250  ?  724 HOH A O    1 
HETATM 5906 O O    . HOH B 2 .   ? 25.56641  -0.20579  12.35470  1.000 40.07879  ?  725 HOH A O    1 
HETATM 5907 O O    . HOH B 2 .   ? 0.81011   -20.06417 -25.32357 1.000 42.01674  ?  726 HOH A O    1 
HETATM 5908 O O    . HOH B 2 .   ? 40.48527  -10.96204 -14.61632 1.000 41.80471  ?  727 HOH A O    1 
HETATM 5909 O O    . HOH B 2 .   ? 6.06794   -12.27673 -6.42540  1.000 44.19714  ?  728 HOH A O    1 
HETATM 5910 O O    . HOH B 2 .   ? 25.09742  -17.82973 -33.95675 1.000 41.25626  ?  729 HOH A O    1 
HETATM 5911 O O    . HOH B 2 .   ? 9.77503   -34.47254 -9.19994  1.000 42.87584  ?  730 HOH A O    1 
HETATM 5912 O O    . HOH B 2 .   ? 37.17373  -22.40670 -21.72676 1.000 38.66520  ?  731 HOH A O    1 
HETATM 5913 O O    . HOH B 2 .   ? 23.44842  7.62761   -28.97034 1.000 35.90813  ?  732 HOH A O    1 
HETATM 5914 O O    . HOH B 2 .   ? 26.97885  7.73319   -2.76177  1.000 39.05697  ?  733 HOH A O    1 
HETATM 5915 O O    . HOH B 2 .   ? 8.16730   -3.79288  -0.42877  1.000 45.21811  ?  734 HOH A O    1 
HETATM 5916 O O    . HOH B 2 .   ? 17.01053  -0.38095  5.16503   1.000 43.02084  ?  735 HOH A O    1 
HETATM 5917 O O    . HOH B 2 .   ? 34.33717  -8.60803  -3.44273  1.000 37.65430  ?  736 HOH A O    1 
HETATM 5918 O O    . HOH B 2 .   ? 8.89581   -21.97003 -28.70913 1.000 44.70304  ?  737 HOH A O    1 
HETATM 5919 O O    . HOH B 2 .   ? 29.45908  -24.29518 -3.63903  1.000 43.85938  ?  738 HOH A O    1 
HETATM 5920 O O    . HOH B 2 .   ? 37.07445  0.19919   -30.74587 1.000 33.96485  ?  739 HOH A O    1 
HETATM 5921 O O    . HOH B 2 .   ? 30.804    -0.569    3.426     1.000 32.92533  ?  740 HOH A O    1 
HETATM 5922 O O    . HOH B 2 .   ? 12.46857  -23.80671 -22.90739 1.000 40.81005  ?  741 HOH A O    1 
HETATM 5923 O O    . HOH B 2 .   ? 20.98347  -3.18019  -19.44609 1.000 32.80021  ?  742 HOH A O    1 
HETATM 5924 O O    . HOH B 2 .   ? 25.46671  5.49330   -29.21924 1.000 27.14832  ?  743 HOH A O    1 
HETATM 5925 O O    . HOH B 2 .   ? 15.38639  -6.35029  5.57388   1.000 41.73588  ?  744 HOH A O    1 
HETATM 5926 O O    . HOH B 2 .   ? 7.91465   -23.21590 -22.75205 1.000 44.18368  ?  745 HOH A O    1 
HETATM 5927 O O    . HOH B 2 .   ? -3.44546  -6.62091  -12.03855 1.000 42.43125  ?  746 HOH A O    1 
# 
