data_8W3R
# 
_entry.id   8W3R 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.401 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   8W3R         pdb_00008w3r 10.2210/pdb8w3r/pdb 
WWPDB D_1000280353 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-01-15 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        8W3R 
_pdbx_database_status.recvd_initial_deposition_date   2024-02-22 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              jiang@scripps.edu 
_pdbx_contact_author.name_first         JIANG 
_pdbx_contact_author.name_last          ZHU 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-0259-7157 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Lee, Y.Z.'       1 ? 
'Stanfield, R.L.' 2 ? 
'Wilson, I.A.'    3 ? 
'Zhu, J.'         4 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            15 
_citation.language                  ? 
_citation.page_first                9939 
_citation.page_last                 9939 
_citation.title                     
'Rational design of uncleaved prefusion-closed trimer vaccines for human respiratory syncytial virus and metapneumovirus.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-024-54287-x 
_citation.pdbx_database_id_PubMed   39550381 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Lee, Y.Z.'       1  0000-0002-5651-863X 
primary 'Han, J.'         2  ?                   
primary 'Zhang, Y.N.'     3  0000-0001-9053-5890 
primary 'Ward, G.'        4  ?                   
primary 'Braz Gomes, K.'  5  ?                   
primary 'Auclair, S.'     6  ?                   
primary 'Stanfield, R.L.' 7  ?                   
primary 'He, L.'          8  ?                   
primary 'Wilson, I.A.'    9  0000-0002-6469-2419 
primary 'Zhu, J.'         10 0000-0003-0259-7157 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'A4 single-chain fragment variable'                  28327.896 1 ? ? ? ? 
2 polymer     man 'prefusion-stabilized RSV F protein UFCR2-iSS-P2-NQ' 55649.660 1 ? ? ? ? 
3 non-polymer syn 2-acetamido-2-deoxy-beta-D-glucopyranose             221.208   1 ? ? ? ? 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;EVQLVESGGGLVQPGGSLRLSCAASGFTFTTYAMHWVRQSPGKGLEWLASISYDGTSQYYAESVKGRFTVSRDNSKKTLL
LQVNSLRPEDTAVYYCAGSPSGHYSWLGYFYAMDVWGQGTVTVSSGGGGSGGGGSGGGGSQSALTQPASVSGSPGQSITI
SCTGASSDVGGYDYVSWYQQHPGKAPKLLIYDVSDRPSGVSNRFSGSKSGNTASLTISGLQTEDEADYYCSSYTSKNTLI
FGGGTKLTVLTSGPGGPEPKSSDKGSHHHHHH
;
;EVQLVESGGGLVQPGGSLRLSCAASGFTFTTYAMHWVRQSPGKGLEWLASISYDGTSQYYAESVKGRFTVSRDNSKKTLL
LQVNSLRPEDTAVYYCAGSPSGHYSWLGYFYAMDVWGQGTVTVSSGGGGSGGGGSGGGGSQSALTQPASVSGSPGQSITI
SCTGASSDVGGYDYVSWYQQHPGKAPKLLIYDVSDRPSGVSNRFSGSKSGNTASLTISGLQTEDEADYYCSSYTSKNTLI
FGGGTKLTVLTSGPGGPEPKSSDKGSHHHHHH
;
A ? 
2 'polypeptide(L)' no no 
;MGILPSPGMPALLSLVSLLSVLLMGCVAEQNITEEFYQSTCSAVSKGYLGALRTGWYTSVITIELSNIKENKCNGTDAKV
KLIKQELDKYKNAVTDLQLLMQSTPATGSGSAICSGVAVCKVLHLEGEVNKIKSALLSTNKAVVSLSNGPSVLTSKVLDL
KNYIDKQLLPIVNKQSCSIPNIETVIEFQQKNNRLLEITREFSVNAGVTTPVSTYMLTNSELLSLINDMPITNDQKKLMS
NNVQIVRQQSYSIMCIIKEEVLAYVVQLPLYGVIDTPCWKLHTSPLCTTNTKEGSNICLTRTDRGWYCDNAGSVSFFPQA
ETCKVQSNRVFCDTMNSLTLPSEVNLCNVDIFNPKYDCKIMTSKTDVSSSVITSLGAIVSCYGKTKCTASNKNRGIIKTF
SNGCDYVSNKGVDTVSVGNTLYCVNKQEGQSLYVKGEPIINFYDPLVFPSNQFDASISQVNEKINQSLAFIRKSDELLAS
GYIPEAPRDGQAYVRKDGEWVLLSTFL
;
;MGILPSPGMPALLSLVSLLSVLLMGCVAEQNITEEFYQSTCSAVSKGYLGALRTGWYTSVITIELSNIKENKCNGTDAKV
KLIKQELDKYKNAVTDLQLLMQSTPATGSGSAICSGVAVCKVLHLEGEVNKIKSALLSTNKAVVSLSNGPSVLTSKVLDL
KNYIDKQLLPIVNKQSCSIPNIETVIEFQQKNNRLLEITREFSVNAGVTTPVSTYMLTNSELLSLINDMPITNDQKKLMS
NNVQIVRQQSYSIMCIIKEEVLAYVVQLPLYGVIDTPCWKLHTSPLCTTNTKEGSNICLTRTDRGWYCDNAGSVSFFPQA
ETCKVQSNRVFCDTMNSLTLPSEVNLCNVDIFNPKYDCKIMTSKTDVSSSVITSLGAIVSCYGKTKCTASNKNRGIIKTF
SNGCDYVSNKGVDTVSVGNTLYCVNKQEGQSLYVKGEPIINFYDPLVFPSNQFDASISQVNEKINQSLAFIRKSDELLAS
GYIPEAPRDGQAYVRKDGEWVLLSTFL
;
F ? 
# 
_pdbx_entity_nonpoly.entity_id   3 
_pdbx_entity_nonpoly.name        2-acetamido-2-deoxy-beta-D-glucopyranose 
_pdbx_entity_nonpoly.comp_id     NAG 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLU n 
1 2   VAL n 
1 3   GLN n 
1 4   LEU n 
1 5   VAL n 
1 6   GLU n 
1 7   SER n 
1 8   GLY n 
1 9   GLY n 
1 10  GLY n 
1 11  LEU n 
1 12  VAL n 
1 13  GLN n 
1 14  PRO n 
1 15  GLY n 
1 16  GLY n 
1 17  SER n 
1 18  LEU n 
1 19  ARG n 
1 20  LEU n 
1 21  SER n 
1 22  CYS n 
1 23  ALA n 
1 24  ALA n 
1 25  SER n 
1 26  GLY n 
1 27  PHE n 
1 28  THR n 
1 29  PHE n 
1 30  THR n 
1 31  THR n 
1 32  TYR n 
1 33  ALA n 
1 34  MET n 
1 35  HIS n 
1 36  TRP n 
1 37  VAL n 
1 38  ARG n 
1 39  GLN n 
1 40  SER n 
1 41  PRO n 
1 42  GLY n 
1 43  LYS n 
1 44  GLY n 
1 45  LEU n 
1 46  GLU n 
1 47  TRP n 
1 48  LEU n 
1 49  ALA n 
1 50  SER n 
1 51  ILE n 
1 52  SER n 
1 53  TYR n 
1 54  ASP n 
1 55  GLY n 
1 56  THR n 
1 57  SER n 
1 58  GLN n 
1 59  TYR n 
1 60  TYR n 
1 61  ALA n 
1 62  GLU n 
1 63  SER n 
1 64  VAL n 
1 65  LYS n 
1 66  GLY n 
1 67  ARG n 
1 68  PHE n 
1 69  THR n 
1 70  VAL n 
1 71  SER n 
1 72  ARG n 
1 73  ASP n 
1 74  ASN n 
1 75  SER n 
1 76  LYS n 
1 77  LYS n 
1 78  THR n 
1 79  LEU n 
1 80  LEU n 
1 81  LEU n 
1 82  GLN n 
1 83  VAL n 
1 84  ASN n 
1 85  SER n 
1 86  LEU n 
1 87  ARG n 
1 88  PRO n 
1 89  GLU n 
1 90  ASP n 
1 91  THR n 
1 92  ALA n 
1 93  VAL n 
1 94  TYR n 
1 95  TYR n 
1 96  CYS n 
1 97  ALA n 
1 98  GLY n 
1 99  SER n 
1 100 PRO n 
1 101 SER n 
1 102 GLY n 
1 103 HIS n 
1 104 TYR n 
1 105 SER n 
1 106 TRP n 
1 107 LEU n 
1 108 GLY n 
1 109 TYR n 
1 110 PHE n 
1 111 TYR n 
1 112 ALA n 
1 113 MET n 
1 114 ASP n 
1 115 VAL n 
1 116 TRP n 
1 117 GLY n 
1 118 GLN n 
1 119 GLY n 
1 120 THR n 
1 121 VAL n 
1 122 THR n 
1 123 VAL n 
1 124 SER n 
1 125 SER n 
1 126 GLY n 
1 127 GLY n 
1 128 GLY n 
1 129 GLY n 
1 130 SER n 
1 131 GLY n 
1 132 GLY n 
1 133 GLY n 
1 134 GLY n 
1 135 SER n 
1 136 GLY n 
1 137 GLY n 
1 138 GLY n 
1 139 GLY n 
1 140 SER n 
1 141 GLN n 
1 142 SER n 
1 143 ALA n 
1 144 LEU n 
1 145 THR n 
1 146 GLN n 
1 147 PRO n 
1 148 ALA n 
1 149 SER n 
1 150 VAL n 
1 151 SER n 
1 152 GLY n 
1 153 SER n 
1 154 PRO n 
1 155 GLY n 
1 156 GLN n 
1 157 SER n 
1 158 ILE n 
1 159 THR n 
1 160 ILE n 
1 161 SER n 
1 162 CYS n 
1 163 THR n 
1 164 GLY n 
1 165 ALA n 
1 166 SER n 
1 167 SER n 
1 168 ASP n 
1 169 VAL n 
1 170 GLY n 
1 171 GLY n 
1 172 TYR n 
1 173 ASP n 
1 174 TYR n 
1 175 VAL n 
1 176 SER n 
1 177 TRP n 
1 178 TYR n 
1 179 GLN n 
1 180 GLN n 
1 181 HIS n 
1 182 PRO n 
1 183 GLY n 
1 184 LYS n 
1 185 ALA n 
1 186 PRO n 
1 187 LYS n 
1 188 LEU n 
1 189 LEU n 
1 190 ILE n 
1 191 TYR n 
1 192 ASP n 
1 193 VAL n 
1 194 SER n 
1 195 ASP n 
1 196 ARG n 
1 197 PRO n 
1 198 SER n 
1 199 GLY n 
1 200 VAL n 
1 201 SER n 
1 202 ASN n 
1 203 ARG n 
1 204 PHE n 
1 205 SER n 
1 206 GLY n 
1 207 SER n 
1 208 LYS n 
1 209 SER n 
1 210 GLY n 
1 211 ASN n 
1 212 THR n 
1 213 ALA n 
1 214 SER n 
1 215 LEU n 
1 216 THR n 
1 217 ILE n 
1 218 SER n 
1 219 GLY n 
1 220 LEU n 
1 221 GLN n 
1 222 THR n 
1 223 GLU n 
1 224 ASP n 
1 225 GLU n 
1 226 ALA n 
1 227 ASP n 
1 228 TYR n 
1 229 TYR n 
1 230 CYS n 
1 231 SER n 
1 232 SER n 
1 233 TYR n 
1 234 THR n 
1 235 SER n 
1 236 LYS n 
1 237 ASN n 
1 238 THR n 
1 239 LEU n 
1 240 ILE n 
1 241 PHE n 
1 242 GLY n 
1 243 GLY n 
1 244 GLY n 
1 245 THR n 
1 246 LYS n 
1 247 LEU n 
1 248 THR n 
1 249 VAL n 
1 250 LEU n 
1 251 THR n 
1 252 SER n 
1 253 GLY n 
1 254 PRO n 
1 255 GLY n 
1 256 GLY n 
1 257 PRO n 
1 258 GLU n 
1 259 PRO n 
1 260 LYS n 
1 261 SER n 
1 262 SER n 
1 263 ASP n 
1 264 LYS n 
1 265 GLY n 
1 266 SER n 
1 267 HIS n 
1 268 HIS n 
1 269 HIS n 
1 270 HIS n 
1 271 HIS n 
1 272 HIS n 
2 1   MET n 
2 2   GLY n 
2 3   ILE n 
2 4   LEU n 
2 5   PRO n 
2 6   SER n 
2 7   PRO n 
2 8   GLY n 
2 9   MET n 
2 10  PRO n 
2 11  ALA n 
2 12  LEU n 
2 13  LEU n 
2 14  SER n 
2 15  LEU n 
2 16  VAL n 
2 17  SER n 
2 18  LEU n 
2 19  LEU n 
2 20  SER n 
2 21  VAL n 
2 22  LEU n 
2 23  LEU n 
2 24  MET n 
2 25  GLY n 
2 26  CYS n 
2 27  VAL n 
2 28  ALA n 
2 29  GLU n 
2 30  GLN n 
2 31  ASN n 
2 32  ILE n 
2 33  THR n 
2 34  GLU n 
2 35  GLU n 
2 36  PHE n 
2 37  TYR n 
2 38  GLN n 
2 39  SER n 
2 40  THR n 
2 41  CYS n 
2 42  SER n 
2 43  ALA n 
2 44  VAL n 
2 45  SER n 
2 46  LYS n 
2 47  GLY n 
2 48  TYR n 
2 49  LEU n 
2 50  GLY n 
2 51  ALA n 
2 52  LEU n 
2 53  ARG n 
2 54  THR n 
2 55  GLY n 
2 56  TRP n 
2 57  TYR n 
2 58  THR n 
2 59  SER n 
2 60  VAL n 
2 61  ILE n 
2 62  THR n 
2 63  ILE n 
2 64  GLU n 
2 65  LEU n 
2 66  SER n 
2 67  ASN n 
2 68  ILE n 
2 69  LYS n 
2 70  GLU n 
2 71  ASN n 
2 72  LYS n 
2 73  CYS n 
2 74  ASN n 
2 75  GLY n 
2 76  THR n 
2 77  ASP n 
2 78  ALA n 
2 79  LYS n 
2 80  VAL n 
2 81  LYS n 
2 82  LEU n 
2 83  ILE n 
2 84  LYS n 
2 85  GLN n 
2 86  GLU n 
2 87  LEU n 
2 88  ASP n 
2 89  LYS n 
2 90  TYR n 
2 91  LYS n 
2 92  ASN n 
2 93  ALA n 
2 94  VAL n 
2 95  THR n 
2 96  ASP n 
2 97  LEU n 
2 98  GLN n 
2 99  LEU n 
2 100 LEU n 
2 101 MET n 
2 102 GLN n 
2 103 SER n 
2 104 THR n 
2 105 PRO n 
2 106 ALA n 
2 107 THR n 
2 108 GLY n 
2 109 SER n 
2 110 GLY n 
2 111 SER n 
2 112 ALA n 
2 113 ILE n 
2 114 CYS n 
2 115 SER n 
2 116 GLY n 
2 117 VAL n 
2 118 ALA n 
2 119 VAL n 
2 120 CYS n 
2 121 LYS n 
2 122 VAL n 
2 123 LEU n 
2 124 HIS n 
2 125 LEU n 
2 126 GLU n 
2 127 GLY n 
2 128 GLU n 
2 129 VAL n 
2 130 ASN n 
2 131 LYS n 
2 132 ILE n 
2 133 LYS n 
2 134 SER n 
2 135 ALA n 
2 136 LEU n 
2 137 LEU n 
2 138 SER n 
2 139 THR n 
2 140 ASN n 
2 141 LYS n 
2 142 ALA n 
2 143 VAL n 
2 144 VAL n 
2 145 SER n 
2 146 LEU n 
2 147 SER n 
2 148 ASN n 
2 149 GLY n 
2 150 PRO n 
2 151 SER n 
2 152 VAL n 
2 153 LEU n 
2 154 THR n 
2 155 SER n 
2 156 LYS n 
2 157 VAL n 
2 158 LEU n 
2 159 ASP n 
2 160 LEU n 
2 161 LYS n 
2 162 ASN n 
2 163 TYR n 
2 164 ILE n 
2 165 ASP n 
2 166 LYS n 
2 167 GLN n 
2 168 LEU n 
2 169 LEU n 
2 170 PRO n 
2 171 ILE n 
2 172 VAL n 
2 173 ASN n 
2 174 LYS n 
2 175 GLN n 
2 176 SER n 
2 177 CYS n 
2 178 SER n 
2 179 ILE n 
2 180 PRO n 
2 181 ASN n 
2 182 ILE n 
2 183 GLU n 
2 184 THR n 
2 185 VAL n 
2 186 ILE n 
2 187 GLU n 
2 188 PHE n 
2 189 GLN n 
2 190 GLN n 
2 191 LYS n 
2 192 ASN n 
2 193 ASN n 
2 194 ARG n 
2 195 LEU n 
2 196 LEU n 
2 197 GLU n 
2 198 ILE n 
2 199 THR n 
2 200 ARG n 
2 201 GLU n 
2 202 PHE n 
2 203 SER n 
2 204 VAL n 
2 205 ASN n 
2 206 ALA n 
2 207 GLY n 
2 208 VAL n 
2 209 THR n 
2 210 THR n 
2 211 PRO n 
2 212 VAL n 
2 213 SER n 
2 214 THR n 
2 215 TYR n 
2 216 MET n 
2 217 LEU n 
2 218 THR n 
2 219 ASN n 
2 220 SER n 
2 221 GLU n 
2 222 LEU n 
2 223 LEU n 
2 224 SER n 
2 225 LEU n 
2 226 ILE n 
2 227 ASN n 
2 228 ASP n 
2 229 MET n 
2 230 PRO n 
2 231 ILE n 
2 232 THR n 
2 233 ASN n 
2 234 ASP n 
2 235 GLN n 
2 236 LYS n 
2 237 LYS n 
2 238 LEU n 
2 239 MET n 
2 240 SER n 
2 241 ASN n 
2 242 ASN n 
2 243 VAL n 
2 244 GLN n 
2 245 ILE n 
2 246 VAL n 
2 247 ARG n 
2 248 GLN n 
2 249 GLN n 
2 250 SER n 
2 251 TYR n 
2 252 SER n 
2 253 ILE n 
2 254 MET n 
2 255 CYS n 
2 256 ILE n 
2 257 ILE n 
2 258 LYS n 
2 259 GLU n 
2 260 GLU n 
2 261 VAL n 
2 262 LEU n 
2 263 ALA n 
2 264 TYR n 
2 265 VAL n 
2 266 VAL n 
2 267 GLN n 
2 268 LEU n 
2 269 PRO n 
2 270 LEU n 
2 271 TYR n 
2 272 GLY n 
2 273 VAL n 
2 274 ILE n 
2 275 ASP n 
2 276 THR n 
2 277 PRO n 
2 278 CYS n 
2 279 TRP n 
2 280 LYS n 
2 281 LEU n 
2 282 HIS n 
2 283 THR n 
2 284 SER n 
2 285 PRO n 
2 286 LEU n 
2 287 CYS n 
2 288 THR n 
2 289 THR n 
2 290 ASN n 
2 291 THR n 
2 292 LYS n 
2 293 GLU n 
2 294 GLY n 
2 295 SER n 
2 296 ASN n 
2 297 ILE n 
2 298 CYS n 
2 299 LEU n 
2 300 THR n 
2 301 ARG n 
2 302 THR n 
2 303 ASP n 
2 304 ARG n 
2 305 GLY n 
2 306 TRP n 
2 307 TYR n 
2 308 CYS n 
2 309 ASP n 
2 310 ASN n 
2 311 ALA n 
2 312 GLY n 
2 313 SER n 
2 314 VAL n 
2 315 SER n 
2 316 PHE n 
2 317 PHE n 
2 318 PRO n 
2 319 GLN n 
2 320 ALA n 
2 321 GLU n 
2 322 THR n 
2 323 CYS n 
2 324 LYS n 
2 325 VAL n 
2 326 GLN n 
2 327 SER n 
2 328 ASN n 
2 329 ARG n 
2 330 VAL n 
2 331 PHE n 
2 332 CYS n 
2 333 ASP n 
2 334 THR n 
2 335 MET n 
2 336 ASN n 
2 337 SER n 
2 338 LEU n 
2 339 THR n 
2 340 LEU n 
2 341 PRO n 
2 342 SER n 
2 343 GLU n 
2 344 VAL n 
2 345 ASN n 
2 346 LEU n 
2 347 CYS n 
2 348 ASN n 
2 349 VAL n 
2 350 ASP n 
2 351 ILE n 
2 352 PHE n 
2 353 ASN n 
2 354 PRO n 
2 355 LYS n 
2 356 TYR n 
2 357 ASP n 
2 358 CYS n 
2 359 LYS n 
2 360 ILE n 
2 361 MET n 
2 362 THR n 
2 363 SER n 
2 364 LYS n 
2 365 THR n 
2 366 ASP n 
2 367 VAL n 
2 368 SER n 
2 369 SER n 
2 370 SER n 
2 371 VAL n 
2 372 ILE n 
2 373 THR n 
2 374 SER n 
2 375 LEU n 
2 376 GLY n 
2 377 ALA n 
2 378 ILE n 
2 379 VAL n 
2 380 SER n 
2 381 CYS n 
2 382 TYR n 
2 383 GLY n 
2 384 LYS n 
2 385 THR n 
2 386 LYS n 
2 387 CYS n 
2 388 THR n 
2 389 ALA n 
2 390 SER n 
2 391 ASN n 
2 392 LYS n 
2 393 ASN n 
2 394 ARG n 
2 395 GLY n 
2 396 ILE n 
2 397 ILE n 
2 398 LYS n 
2 399 THR n 
2 400 PHE n 
2 401 SER n 
2 402 ASN n 
2 403 GLY n 
2 404 CYS n 
2 405 ASP n 
2 406 TYR n 
2 407 VAL n 
2 408 SER n 
2 409 ASN n 
2 410 LYS n 
2 411 GLY n 
2 412 VAL n 
2 413 ASP n 
2 414 THR n 
2 415 VAL n 
2 416 SER n 
2 417 VAL n 
2 418 GLY n 
2 419 ASN n 
2 420 THR n 
2 421 LEU n 
2 422 TYR n 
2 423 CYS n 
2 424 VAL n 
2 425 ASN n 
2 426 LYS n 
2 427 GLN n 
2 428 GLU n 
2 429 GLY n 
2 430 GLN n 
2 431 SER n 
2 432 LEU n 
2 433 TYR n 
2 434 VAL n 
2 435 LYS n 
2 436 GLY n 
2 437 GLU n 
2 438 PRO n 
2 439 ILE n 
2 440 ILE n 
2 441 ASN n 
2 442 PHE n 
2 443 TYR n 
2 444 ASP n 
2 445 PRO n 
2 446 LEU n 
2 447 VAL n 
2 448 PHE n 
2 449 PRO n 
2 450 SER n 
2 451 ASN n 
2 452 GLN n 
2 453 PHE n 
2 454 ASP n 
2 455 ALA n 
2 456 SER n 
2 457 ILE n 
2 458 SER n 
2 459 GLN n 
2 460 VAL n 
2 461 ASN n 
2 462 GLU n 
2 463 LYS n 
2 464 ILE n 
2 465 ASN n 
2 466 GLN n 
2 467 SER n 
2 468 LEU n 
2 469 ALA n 
2 470 PHE n 
2 471 ILE n 
2 472 ARG n 
2 473 LYS n 
2 474 SER n 
2 475 ASP n 
2 476 GLU n 
2 477 LEU n 
2 478 LEU n 
2 479 ALA n 
2 480 SER n 
2 481 GLY n 
2 482 TYR n 
2 483 ILE n 
2 484 PRO n 
2 485 GLU n 
2 486 ALA n 
2 487 PRO n 
2 488 ARG n 
2 489 ASP n 
2 490 GLY n 
2 491 GLN n 
2 492 ALA n 
2 493 TYR n 
2 494 VAL n 
2 495 ARG n 
2 496 LYS n 
2 497 ASP n 
2 498 GLY n 
2 499 GLU n 
2 500 TRP n 
2 501 VAL n 
2 502 LEU n 
2 503 LEU n 
2 504 SER n 
2 505 THR n 
2 506 PHE n 
2 507 LEU n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1 272 ?     ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Homo sapiens'       9606  ? ? ? 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1 507 human ? ? ? ? ? ? ? ? 'Homo sapiens' 9606 ? ? ? ? ? ? ? ? 'Cricetulus griseus' 10029 ? ? ? 
? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking'          y ALANINE                                  ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking'          y ARGININE                                 ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking'          y ASPARAGINE                               ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking'          y 'ASPARTIC ACID'                          ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking'          y CYSTEINE                                 ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking'          y GLUTAMINE                                ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking'          y 'GLUTAMIC ACID'                          ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'            y GLYCINE                                  ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking'          y HISTIDINE                                ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking'          y ISOLEUCINE                               ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking'          y LEUCINE                                  ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking'          y LYSINE                                   ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking'          y METHIONINE                               ? 'C5 H11 N O2 S'  149.211 
NAG 'D-saccharide, beta linking' . 2-acetamido-2-deoxy-beta-D-glucopyranose 
;N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE
;
'C8 H15 N O6'    221.208 
PHE 'L-peptide linking'          y PHENYLALANINE                            ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking'          y PROLINE                                  ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking'          y SERINE                                   ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking'          y THREONINE                                ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking'          y TRYPTOPHAN                               ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking'          y TYROSINE                                 ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking'          y VALINE                                   ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
NAG 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpNAcb                      
NAG 'COMMON NAME'                         GMML     1.0 N-acetyl-b-D-glucopyranosamine 
NAG 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-GlcpNAc                    
NAG 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GlcNAc                         
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLU 1   1   1   GLU GLU A . n 
A 1 2   VAL 2   2   2   VAL VAL A . n 
A 1 3   GLN 3   3   3   GLN GLN A . n 
A 1 4   LEU 4   4   4   LEU LEU A . n 
A 1 5   VAL 5   5   5   VAL VAL A . n 
A 1 6   GLU 6   6   6   GLU GLU A . n 
A 1 7   SER 7   7   7   SER SER A . n 
A 1 8   GLY 8   8   8   GLY GLY A . n 
A 1 9   GLY 9   9   9   GLY GLY A . n 
A 1 10  GLY 10  10  10  GLY GLY A . n 
A 1 11  LEU 11  11  11  LEU LEU A . n 
A 1 12  VAL 12  12  12  VAL VAL A . n 
A 1 13  GLN 13  13  13  GLN GLN A . n 
A 1 14  PRO 14  14  14  PRO PRO A . n 
A 1 15  GLY 15  15  15  GLY GLY A . n 
A 1 16  GLY 16  16  16  GLY GLY A . n 
A 1 17  SER 17  17  17  SER SER A . n 
A 1 18  LEU 18  18  18  LEU LEU A . n 
A 1 19  ARG 19  19  19  ARG ARG A . n 
A 1 20  LEU 20  20  20  LEU LEU A . n 
A 1 21  SER 21  21  21  SER SER A . n 
A 1 22  CYS 22  22  22  CYS CYS A . n 
A 1 23  ALA 23  23  23  ALA ALA A . n 
A 1 24  ALA 24  24  24  ALA ALA A . n 
A 1 25  SER 25  25  25  SER SER A . n 
A 1 26  GLY 26  26  26  GLY GLY A . n 
A 1 27  PHE 27  27  27  PHE PHE A . n 
A 1 28  THR 28  28  28  THR THR A . n 
A 1 29  PHE 29  29  29  PHE PHE A . n 
A 1 30  THR 30  30  30  THR THR A . n 
A 1 31  THR 31  31  31  THR THR A . n 
A 1 32  TYR 32  32  32  TYR TYR A . n 
A 1 33  ALA 33  33  33  ALA ALA A . n 
A 1 34  MET 34  34  34  MET MET A . n 
A 1 35  HIS 35  35  35  HIS HIS A . n 
A 1 36  TRP 36  36  36  TRP TRP A . n 
A 1 37  VAL 37  37  37  VAL VAL A . n 
A 1 38  ARG 38  38  38  ARG ARG A . n 
A 1 39  GLN 39  39  39  GLN GLN A . n 
A 1 40  SER 40  40  40  SER SER A . n 
A 1 41  PRO 41  41  41  PRO PRO A . n 
A 1 42  GLY 42  42  42  GLY GLY A . n 
A 1 43  LYS 43  43  43  LYS LYS A . n 
A 1 44  GLY 44  44  44  GLY GLY A . n 
A 1 45  LEU 45  45  45  LEU LEU A . n 
A 1 46  GLU 46  46  46  GLU GLU A . n 
A 1 47  TRP 47  47  47  TRP TRP A . n 
A 1 48  LEU 48  48  48  LEU LEU A . n 
A 1 49  ALA 49  49  49  ALA ALA A . n 
A 1 50  SER 50  50  50  SER SER A . n 
A 1 51  ILE 51  51  51  ILE ILE A . n 
A 1 52  SER 52  52  52  SER SER A . n 
A 1 53  TYR 53  52  52  TYR TYR A A n 
A 1 54  ASP 54  53  53  ASP ASP A . n 
A 1 55  GLY 55  54  54  GLY GLY A . n 
A 1 56  THR 56  55  55  THR THR A . n 
A 1 57  SER 57  56  56  SER SER A . n 
A 1 58  GLN 58  57  57  GLN GLN A . n 
A 1 59  TYR 59  58  58  TYR TYR A . n 
A 1 60  TYR 60  59  59  TYR TYR A . n 
A 1 61  ALA 61  60  60  ALA ALA A . n 
A 1 62  GLU 62  61  61  GLU GLU A . n 
A 1 63  SER 63  62  62  SER SER A . n 
A 1 64  VAL 64  63  63  VAL VAL A . n 
A 1 65  LYS 65  64  64  LYS LYS A . n 
A 1 66  GLY 66  65  65  GLY GLY A . n 
A 1 67  ARG 67  66  66  ARG ARG A . n 
A 1 68  PHE 68  67  67  PHE PHE A . n 
A 1 69  THR 69  68  68  THR THR A . n 
A 1 70  VAL 70  69  69  VAL VAL A . n 
A 1 71  SER 71  70  70  SER SER A . n 
A 1 72  ARG 72  71  71  ARG ARG A . n 
A 1 73  ASP 73  72  72  ASP ASP A . n 
A 1 74  ASN 74  73  73  ASN ASN A . n 
A 1 75  SER 75  74  74  SER SER A . n 
A 1 76  LYS 76  75  75  LYS LYS A . n 
A 1 77  LYS 77  76  76  LYS LYS A . n 
A 1 78  THR 78  77  77  THR THR A . n 
A 1 79  LEU 79  78  78  LEU LEU A . n 
A 1 80  LEU 80  79  79  LEU LEU A . n 
A 1 81  LEU 81  80  80  LEU LEU A . n 
A 1 82  GLN 82  81  81  GLN GLN A . n 
A 1 83  VAL 83  82  82  VAL VAL A . n 
A 1 84  ASN 84  83  83  ASN ASN A A n 
A 1 85  SER 85  83  83  SER SER A B n 
A 1 86  LEU 86  83  83  LEU LEU A C n 
A 1 87  ARG 87  84  84  ARG ARG A . n 
A 1 88  PRO 88  85  85  PRO PRO A . n 
A 1 89  GLU 89  86  86  GLU GLU A . n 
A 1 90  ASP 90  87  87  ASP ASP A . n 
A 1 91  THR 91  88  88  THR THR A . n 
A 1 92  ALA 92  89  89  ALA ALA A . n 
A 1 93  VAL 93  90  90  VAL VAL A . n 
A 1 94  TYR 94  91  91  TYR TYR A . n 
A 1 95  TYR 95  92  92  TYR TYR A . n 
A 1 96  CYS 96  93  93  CYS CYS A . n 
A 1 97  ALA 97  94  94  ALA ALA A . n 
A 1 98  GLY 98  95  95  GLY GLY A . n 
A 1 99  SER 99  96  96  SER SER A . n 
A 1 100 PRO 100 97  97  PRO PRO A . n 
A 1 101 SER 101 98  98  SER SER A . n 
A 1 102 GLY 102 99  99  GLY GLY A . n 
A 1 103 HIS 103 100 100 HIS HIS A . n 
A 1 104 TYR 104 100 100 TYR TYR A A n 
A 1 105 SER 105 100 100 SER SER A B n 
A 1 106 TRP 106 100 100 TRP TRP A C n 
A 1 107 LEU 107 100 100 LEU LEU A D n 
A 1 108 GLY 108 100 100 GLY GLY A E n 
A 1 109 TYR 109 100 100 TYR TYR A F n 
A 1 110 PHE 110 100 100 PHE PHE A G n 
A 1 111 TYR 111 100 100 TYR TYR A H n 
A 1 112 ALA 112 100 100 ALA ALA A I n 
A 1 113 MET 113 100 100 MET MET A J n 
A 1 114 ASP 114 101 101 ASP ASP A . n 
A 1 115 VAL 115 102 102 VAL VAL A . n 
A 1 116 TRP 116 103 103 TRP TRP A . n 
A 1 117 GLY 117 104 104 GLY GLY A . n 
A 1 118 GLN 118 105 105 GLN GLN A . n 
A 1 119 GLY 119 106 106 GLY GLY A . n 
A 1 120 THR 120 107 107 THR THR A . n 
A 1 121 VAL 121 108 108 VAL VAL A . n 
A 1 122 THR 122 109 109 THR THR A . n 
A 1 123 VAL 123 110 110 VAL VAL A . n 
A 1 124 SER 124 111 111 SER SER A . n 
A 1 125 SER 125 112 112 SER SER A . n 
A 1 126 GLY 126 113 113 GLY GLY A . n 
A 1 127 GLY 127 114 ?   ?   ?   A . n 
A 1 128 GLY 128 115 ?   ?   ?   A . n 
A 1 129 GLY 129 116 ?   ?   ?   A . n 
A 1 130 SER 130 117 ?   ?   ?   A . n 
A 1 131 GLY 131 118 ?   ?   ?   A . n 
A 1 132 GLY 132 119 ?   ?   ?   A . n 
A 1 133 GLY 133 120 ?   ?   ?   A . n 
A 1 134 GLY 134 121 ?   ?   ?   A . n 
A 1 135 SER 135 122 ?   ?   ?   A . n 
A 1 136 GLY 136 123 ?   ?   ?   A . n 
A 1 137 GLY 137 124 ?   ?   ?   A . n 
A 1 138 GLY 138 125 ?   ?   ?   A . n 
A 1 139 GLY 139 126 ?   ?   ?   A . n 
A 1 140 SER 140 127 ?   ?   ?   A . n 
A 1 141 GLN 141 128 128 GLN GLN A . n 
A 1 142 SER 142 129 129 SER SER A . n 
A 1 143 ALA 143 130 130 ALA ALA A . n 
A 1 144 LEU 144 131 131 LEU LEU A . n 
A 1 145 THR 145 132 132 THR THR A . n 
A 1 146 GLN 146 133 133 GLN GLN A . n 
A 1 147 PRO 147 134 134 PRO PRO A . n 
A 1 148 ALA 148 135 135 ALA ALA A . n 
A 1 149 SER 149 136 136 SER SER A . n 
A 1 150 VAL 150 137 137 VAL VAL A . n 
A 1 151 SER 151 138 138 SER SER A . n 
A 1 152 GLY 152 139 139 GLY GLY A . n 
A 1 153 SER 153 140 140 SER SER A . n 
A 1 154 PRO 154 141 141 PRO PRO A . n 
A 1 155 GLY 155 142 142 GLY GLY A . n 
A 1 156 GLN 156 143 143 GLN GLN A . n 
A 1 157 SER 157 144 144 SER SER A . n 
A 1 158 ILE 158 145 145 ILE ILE A . n 
A 1 159 THR 159 146 146 THR THR A . n 
A 1 160 ILE 160 147 147 ILE ILE A . n 
A 1 161 SER 161 148 148 SER SER A . n 
A 1 162 CYS 162 149 149 CYS CYS A . n 
A 1 163 THR 163 150 150 THR THR A . n 
A 1 164 GLY 164 151 151 GLY GLY A . n 
A 1 165 ALA 165 152 152 ALA ALA A . n 
A 1 166 SER 166 153 153 SER SER A . n 
A 1 167 SER 167 153 153 SER SER A A n 
A 1 168 ASP 168 153 153 ASP ASP A B n 
A 1 169 VAL 169 153 153 VAL VAL A C n 
A 1 170 GLY 170 154 154 GLY GLY A . n 
A 1 171 GLY 171 155 155 GLY GLY A . n 
A 1 172 TYR 172 156 156 TYR TYR A . n 
A 1 173 ASP 173 157 157 ASP ASP A . n 
A 1 174 TYR 174 158 158 TYR TYR A . n 
A 1 175 VAL 175 159 159 VAL VAL A . n 
A 1 176 SER 176 160 160 SER SER A . n 
A 1 177 TRP 177 161 161 TRP TRP A . n 
A 1 178 TYR 178 162 162 TYR TYR A . n 
A 1 179 GLN 179 163 163 GLN GLN A . n 
A 1 180 GLN 180 164 164 GLN GLN A . n 
A 1 181 HIS 181 165 165 HIS HIS A . n 
A 1 182 PRO 182 166 166 PRO PRO A . n 
A 1 183 GLY 183 167 167 GLY GLY A . n 
A 1 184 LYS 184 168 168 LYS LYS A . n 
A 1 185 ALA 185 169 169 ALA ALA A . n 
A 1 186 PRO 186 170 170 PRO PRO A . n 
A 1 187 LYS 187 171 171 LYS LYS A . n 
A 1 188 LEU 188 172 172 LEU LEU A . n 
A 1 189 LEU 189 173 173 LEU LEU A . n 
A 1 190 ILE 190 174 174 ILE ILE A . n 
A 1 191 TYR 191 175 175 TYR TYR A . n 
A 1 192 ASP 192 176 176 ASP ASP A . n 
A 1 193 VAL 193 177 177 VAL VAL A . n 
A 1 194 SER 194 178 178 SER SER A . n 
A 1 195 ASP 195 179 179 ASP ASP A . n 
A 1 196 ARG 196 180 180 ARG ARG A . n 
A 1 197 PRO 197 181 181 PRO PRO A . n 
A 1 198 SER 198 182 182 SER SER A . n 
A 1 199 GLY 199 183 183 GLY GLY A . n 
A 1 200 VAL 200 184 184 VAL VAL A . n 
A 1 201 SER 201 185 185 SER SER A . n 
A 1 202 ASN 202 186 186 ASN ASN A . n 
A 1 203 ARG 203 187 187 ARG ARG A . n 
A 1 204 PHE 204 188 188 PHE PHE A . n 
A 1 205 SER 205 189 189 SER SER A . n 
A 1 206 GLY 206 190 190 GLY GLY A . n 
A 1 207 SER 207 191 191 SER SER A . n 
A 1 208 LYS 208 192 192 LYS LYS A . n 
A 1 209 SER 209 193 193 SER SER A . n 
A 1 210 GLY 210 194 194 GLY GLY A . n 
A 1 211 ASN 211 195 195 ASN ASN A . n 
A 1 212 THR 212 196 196 THR THR A . n 
A 1 213 ALA 213 197 197 ALA ALA A . n 
A 1 214 SER 214 198 198 SER SER A . n 
A 1 215 LEU 215 199 199 LEU LEU A . n 
A 1 216 THR 216 200 200 THR THR A . n 
A 1 217 ILE 217 201 201 ILE ILE A . n 
A 1 218 SER 218 202 202 SER SER A . n 
A 1 219 GLY 219 203 203 GLY GLY A . n 
A 1 220 LEU 220 204 204 LEU LEU A . n 
A 1 221 GLN 221 205 205 GLN GLN A . n 
A 1 222 THR 222 206 206 THR THR A . n 
A 1 223 GLU 223 207 207 GLU GLU A . n 
A 1 224 ASP 224 208 208 ASP ASP A . n 
A 1 225 GLU 225 209 209 GLU GLU A . n 
A 1 226 ALA 226 210 210 ALA ALA A . n 
A 1 227 ASP 227 211 211 ASP ASP A . n 
A 1 228 TYR 228 212 212 TYR TYR A . n 
A 1 229 TYR 229 213 213 TYR TYR A . n 
A 1 230 CYS 230 214 214 CYS CYS A . n 
A 1 231 SER 231 215 215 SER SER A . n 
A 1 232 SER 232 216 216 SER SER A . n 
A 1 233 TYR 233 217 217 TYR TYR A . n 
A 1 234 THR 234 218 218 THR THR A . n 
A 1 235 SER 235 219 219 SER SER A . n 
A 1 236 LYS 236 220 220 LYS LYS A . n 
A 1 237 ASN 237 221 221 ASN ASN A . n 
A 1 238 THR 238 221 221 THR THR A A n 
A 1 239 LEU 239 222 222 LEU LEU A . n 
A 1 240 ILE 240 223 223 ILE ILE A . n 
A 1 241 PHE 241 224 224 PHE PHE A . n 
A 1 242 GLY 242 225 225 GLY GLY A . n 
A 1 243 GLY 243 226 226 GLY GLY A . n 
A 1 244 GLY 244 227 227 GLY GLY A . n 
A 1 245 THR 245 228 228 THR THR A . n 
A 1 246 LYS 246 229 229 LYS LYS A . n 
A 1 247 LEU 247 230 230 LEU LEU A . n 
A 1 248 THR 248 231 231 THR THR A . n 
A 1 249 VAL 249 232 232 VAL VAL A . n 
A 1 250 LEU 250 233 233 LEU LEU A . n 
A 1 251 THR 251 234 ?   ?   ?   A . n 
A 1 252 SER 252 235 ?   ?   ?   A . n 
A 1 253 GLY 253 236 ?   ?   ?   A . n 
A 1 254 PRO 254 237 ?   ?   ?   A . n 
A 1 255 GLY 255 238 ?   ?   ?   A . n 
A 1 256 GLY 256 239 ?   ?   ?   A . n 
A 1 257 PRO 257 240 ?   ?   ?   A . n 
A 1 258 GLU 258 241 ?   ?   ?   A . n 
A 1 259 PRO 259 242 ?   ?   ?   A . n 
A 1 260 LYS 260 243 ?   ?   ?   A . n 
A 1 261 SER 261 244 ?   ?   ?   A . n 
A 1 262 SER 262 245 ?   ?   ?   A . n 
A 1 263 ASP 263 246 ?   ?   ?   A . n 
A 1 264 LYS 264 247 ?   ?   ?   A . n 
A 1 265 GLY 265 248 ?   ?   ?   A . n 
A 1 266 SER 266 249 ?   ?   ?   A . n 
A 1 267 HIS 267 250 ?   ?   ?   A . n 
A 1 268 HIS 268 251 ?   ?   ?   A . n 
A 1 269 HIS 269 252 ?   ?   ?   A . n 
A 1 270 HIS 270 253 ?   ?   ?   A . n 
A 1 271 HIS 271 254 ?   ?   ?   A . n 
A 1 272 HIS 272 255 ?   ?   ?   A . n 
B 2 1   MET 1   -3  ?   ?   ?   F . n 
B 2 2   GLY 2   -2  ?   ?   ?   F . n 
B 2 3   ILE 3   -1  ?   ?   ?   F . n 
B 2 4   LEU 4   0   ?   ?   ?   F . n 
B 2 5   PRO 5   1   ?   ?   ?   F . n 
B 2 6   SER 6   2   ?   ?   ?   F . n 
B 2 7   PRO 7   3   ?   ?   ?   F . n 
B 2 8   GLY 8   4   ?   ?   ?   F . n 
B 2 9   MET 9   5   ?   ?   ?   F . n 
B 2 10  PRO 10  6   ?   ?   ?   F . n 
B 2 11  ALA 11  7   ?   ?   ?   F . n 
B 2 12  LEU 12  8   ?   ?   ?   F . n 
B 2 13  LEU 13  9   ?   ?   ?   F . n 
B 2 14  SER 14  10  ?   ?   ?   F . n 
B 2 15  LEU 15  11  ?   ?   ?   F . n 
B 2 16  VAL 16  12  ?   ?   ?   F . n 
B 2 17  SER 17  13  ?   ?   ?   F . n 
B 2 18  LEU 18  14  ?   ?   ?   F . n 
B 2 19  LEU 19  15  ?   ?   ?   F . n 
B 2 20  SER 20  16  ?   ?   ?   F . n 
B 2 21  VAL 21  17  ?   ?   ?   F . n 
B 2 22  LEU 22  18  ?   ?   ?   F . n 
B 2 23  LEU 23  19  ?   ?   ?   F . n 
B 2 24  MET 24  20  ?   ?   ?   F . n 
B 2 25  GLY 25  21  ?   ?   ?   F . n 
B 2 26  CYS 26  22  ?   ?   ?   F . n 
B 2 27  VAL 27  23  ?   ?   ?   F . n 
B 2 28  ALA 28  24  ?   ?   ?   F . n 
B 2 29  GLU 29  25  ?   ?   ?   F . n 
B 2 30  GLN 30  26  26  GLN GLN F . n 
B 2 31  ASN 31  27  27  ASN ASN F . n 
B 2 32  ILE 32  28  28  ILE ILE F . n 
B 2 33  THR 33  29  29  THR THR F . n 
B 2 34  GLU 34  30  30  GLU GLU F . n 
B 2 35  GLU 35  31  31  GLU GLU F . n 
B 2 36  PHE 36  32  32  PHE PHE F . n 
B 2 37  TYR 37  33  33  TYR TYR F . n 
B 2 38  GLN 38  34  34  GLN GLN F . n 
B 2 39  SER 39  35  35  SER SER F . n 
B 2 40  THR 40  36  36  THR THR F . n 
B 2 41  CYS 41  37  37  CYS CYS F . n 
B 2 42  SER 42  38  38  SER SER F . n 
B 2 43  ALA 43  39  39  ALA ALA F . n 
B 2 44  VAL 44  40  40  VAL VAL F . n 
B 2 45  SER 45  41  41  SER SER F . n 
B 2 46  LYS 46  42  42  LYS LYS F . n 
B 2 47  GLY 47  43  43  GLY GLY F . n 
B 2 48  TYR 48  44  44  TYR TYR F . n 
B 2 49  LEU 49  45  45  LEU LEU F . n 
B 2 50  GLY 50  46  46  GLY GLY F . n 
B 2 51  ALA 51  47  47  ALA ALA F . n 
B 2 52  LEU 52  48  48  LEU LEU F . n 
B 2 53  ARG 53  49  49  ARG ARG F . n 
B 2 54  THR 54  50  50  THR THR F . n 
B 2 55  GLY 55  51  51  GLY GLY F . n 
B 2 56  TRP 56  52  52  TRP TRP F . n 
B 2 57  TYR 57  53  53  TYR TYR F . n 
B 2 58  THR 58  54  54  THR THR F . n 
B 2 59  SER 59  55  55  SER SER F . n 
B 2 60  VAL 60  56  56  VAL VAL F . n 
B 2 61  ILE 61  57  57  ILE ILE F . n 
B 2 62  THR 62  58  58  THR THR F . n 
B 2 63  ILE 63  59  59  ILE ILE F . n 
B 2 64  GLU 64  60  60  GLU GLU F . n 
B 2 65  LEU 65  61  61  LEU LEU F . n 
B 2 66  SER 66  62  62  SER SER F . n 
B 2 67  ASN 67  63  63  ASN ASN F . n 
B 2 68  ILE 68  64  64  ILE ILE F . n 
B 2 69  LYS 69  65  65  LYS LYS F . n 
B 2 70  GLU 70  66  66  GLU GLU F . n 
B 2 71  ASN 71  67  67  ASN ASN F . n 
B 2 72  LYS 72  68  68  LYS LYS F . n 
B 2 73  CYS 73  69  69  CYS CYS F . n 
B 2 74  ASN 74  70  70  ASN ASN F . n 
B 2 75  GLY 75  71  71  GLY GLY F . n 
B 2 76  THR 76  72  72  THR THR F . n 
B 2 77  ASP 77  73  73  ASP ASP F . n 
B 2 78  ALA 78  74  74  ALA ALA F . n 
B 2 79  LYS 79  75  75  LYS LYS F . n 
B 2 80  VAL 80  76  76  VAL VAL F . n 
B 2 81  LYS 81  77  77  LYS LYS F . n 
B 2 82  LEU 82  78  78  LEU LEU F . n 
B 2 83  ILE 83  79  79  ILE ILE F . n 
B 2 84  LYS 84  80  80  LYS LYS F . n 
B 2 85  GLN 85  81  81  GLN GLN F . n 
B 2 86  GLU 86  82  82  GLU GLU F . n 
B 2 87  LEU 87  83  83  LEU LEU F . n 
B 2 88  ASP 88  84  84  ASP ASP F . n 
B 2 89  LYS 89  85  85  LYS LYS F . n 
B 2 90  TYR 90  86  86  TYR TYR F . n 
B 2 91  LYS 91  87  87  LYS LYS F . n 
B 2 92  ASN 92  88  88  ASN ASN F . n 
B 2 93  ALA 93  89  89  ALA ALA F . n 
B 2 94  VAL 94  90  90  VAL VAL F . n 
B 2 95  THR 95  91  91  THR THR F . n 
B 2 96  ASP 96  92  92  ASP ASP F . n 
B 2 97  LEU 97  93  93  LEU LEU F . n 
B 2 98  GLN 98  94  94  GLN GLN F . n 
B 2 99  LEU 99  95  95  LEU LEU F . n 
B 2 100 LEU 100 96  96  LEU LEU F . n 
B 2 101 MET 101 97  97  MET MET F . n 
B 2 102 GLN 102 98  98  GLN GLN F . n 
B 2 103 SER 103 99  99  SER SER F . n 
B 2 104 THR 104 100 100 THR THR F . n 
B 2 105 PRO 105 101 101 PRO PRO F . n 
B 2 106 ALA 106 102 102 ALA ALA F . n 
B 2 107 THR 107 103 103 THR THR F . n 
B 2 108 GLY 108 143 143 GLY GLY F . n 
B 2 109 SER 109 144 144 SER SER F . n 
B 2 110 GLY 110 145 145 GLY GLY F . n 
B 2 111 SER 111 146 146 SER SER F . n 
B 2 112 ALA 112 147 147 ALA ALA F . n 
B 2 113 ILE 113 148 148 ILE ILE F . n 
B 2 114 CYS 114 149 149 CYS CYS F . n 
B 2 115 SER 115 150 150 SER SER F . n 
B 2 116 GLY 116 151 151 GLY GLY F . n 
B 2 117 VAL 117 152 152 VAL VAL F . n 
B 2 118 ALA 118 153 153 ALA ALA F . n 
B 2 119 VAL 119 154 154 VAL VAL F . n 
B 2 120 CYS 120 155 155 CYS CYS F . n 
B 2 121 LYS 121 156 156 LYS LYS F . n 
B 2 122 VAL 122 157 157 VAL VAL F . n 
B 2 123 LEU 123 158 158 LEU LEU F . n 
B 2 124 HIS 124 159 159 HIS HIS F . n 
B 2 125 LEU 125 160 160 LEU LEU F . n 
B 2 126 GLU 126 161 161 GLU GLU F . n 
B 2 127 GLY 127 162 162 GLY GLY F . n 
B 2 128 GLU 128 163 163 GLU GLU F . n 
B 2 129 VAL 129 164 164 VAL VAL F . n 
B 2 130 ASN 130 165 165 ASN ASN F . n 
B 2 131 LYS 131 166 166 LYS LYS F . n 
B 2 132 ILE 132 167 167 ILE ILE F . n 
B 2 133 LYS 133 168 168 LYS LYS F . n 
B 2 134 SER 134 169 169 SER SER F . n 
B 2 135 ALA 135 170 170 ALA ALA F . n 
B 2 136 LEU 136 171 171 LEU LEU F . n 
B 2 137 LEU 137 172 172 LEU LEU F . n 
B 2 138 SER 138 173 173 SER SER F . n 
B 2 139 THR 139 174 174 THR THR F . n 
B 2 140 ASN 140 175 175 ASN ASN F . n 
B 2 141 LYS 141 176 176 LYS LYS F . n 
B 2 142 ALA 142 177 177 ALA ALA F . n 
B 2 143 VAL 143 178 178 VAL VAL F . n 
B 2 144 VAL 144 179 179 VAL VAL F . n 
B 2 145 SER 145 180 180 SER SER F . n 
B 2 146 LEU 146 181 181 LEU LEU F . n 
B 2 147 SER 147 182 182 SER SER F . n 
B 2 148 ASN 148 183 183 ASN ASN F . n 
B 2 149 GLY 149 184 184 GLY GLY F . n 
B 2 150 PRO 150 185 185 PRO PRO F . n 
B 2 151 SER 151 186 186 SER SER F . n 
B 2 152 VAL 152 187 187 VAL VAL F . n 
B 2 153 LEU 153 188 188 LEU LEU F . n 
B 2 154 THR 154 189 189 THR THR F . n 
B 2 155 SER 155 190 190 SER SER F . n 
B 2 156 LYS 156 191 191 LYS LYS F . n 
B 2 157 VAL 157 192 192 VAL VAL F . n 
B 2 158 LEU 158 193 193 LEU LEU F . n 
B 2 159 ASP 159 194 194 ASP ASP F . n 
B 2 160 LEU 160 195 195 LEU LEU F . n 
B 2 161 LYS 161 196 196 LYS LYS F . n 
B 2 162 ASN 162 197 197 ASN ASN F . n 
B 2 163 TYR 163 198 198 TYR TYR F . n 
B 2 164 ILE 164 199 199 ILE ILE F . n 
B 2 165 ASP 165 200 200 ASP ASP F . n 
B 2 166 LYS 166 201 201 LYS LYS F . n 
B 2 167 GLN 167 202 202 GLN GLN F . n 
B 2 168 LEU 168 203 203 LEU LEU F . n 
B 2 169 LEU 169 204 204 LEU LEU F . n 
B 2 170 PRO 170 205 205 PRO PRO F . n 
B 2 171 ILE 171 206 206 ILE ILE F . n 
B 2 172 VAL 172 207 207 VAL VAL F . n 
B 2 173 ASN 173 208 208 ASN ASN F . n 
B 2 174 LYS 174 209 209 LYS LYS F . n 
B 2 175 GLN 175 210 210 GLN GLN F . n 
B 2 176 SER 176 211 211 SER SER F . n 
B 2 177 CYS 177 212 212 CYS CYS F . n 
B 2 178 SER 178 213 213 SER SER F . n 
B 2 179 ILE 179 214 214 ILE ILE F . n 
B 2 180 PRO 180 215 215 PRO PRO F . n 
B 2 181 ASN 181 216 216 ASN ASN F . n 
B 2 182 ILE 182 217 217 ILE ILE F . n 
B 2 183 GLU 183 218 218 GLU GLU F . n 
B 2 184 THR 184 219 219 THR THR F . n 
B 2 185 VAL 185 220 220 VAL VAL F . n 
B 2 186 ILE 186 221 221 ILE ILE F . n 
B 2 187 GLU 187 222 222 GLU GLU F . n 
B 2 188 PHE 188 223 223 PHE PHE F . n 
B 2 189 GLN 189 224 224 GLN GLN F . n 
B 2 190 GLN 190 225 225 GLN GLN F . n 
B 2 191 LYS 191 226 226 LYS LYS F . n 
B 2 192 ASN 192 227 227 ASN ASN F . n 
B 2 193 ASN 193 228 228 ASN ASN F . n 
B 2 194 ARG 194 229 229 ARG ARG F . n 
B 2 195 LEU 195 230 230 LEU LEU F . n 
B 2 196 LEU 196 231 231 LEU LEU F . n 
B 2 197 GLU 197 232 232 GLU GLU F . n 
B 2 198 ILE 198 233 233 ILE ILE F . n 
B 2 199 THR 199 234 234 THR THR F . n 
B 2 200 ARG 200 235 235 ARG ARG F . n 
B 2 201 GLU 201 236 236 GLU GLU F . n 
B 2 202 PHE 202 237 237 PHE PHE F . n 
B 2 203 SER 203 238 238 SER SER F . n 
B 2 204 VAL 204 239 239 VAL VAL F . n 
B 2 205 ASN 205 240 240 ASN ASN F . n 
B 2 206 ALA 206 241 241 ALA ALA F . n 
B 2 207 GLY 207 242 242 GLY GLY F . n 
B 2 208 VAL 208 243 243 VAL VAL F . n 
B 2 209 THR 209 244 244 THR THR F . n 
B 2 210 THR 210 245 245 THR THR F . n 
B 2 211 PRO 211 246 246 PRO PRO F . n 
B 2 212 VAL 212 247 247 VAL VAL F . n 
B 2 213 SER 213 248 248 SER SER F . n 
B 2 214 THR 214 249 249 THR THR F . n 
B 2 215 TYR 215 250 250 TYR TYR F . n 
B 2 216 MET 216 251 251 MET MET F . n 
B 2 217 LEU 217 252 252 LEU LEU F . n 
B 2 218 THR 218 253 253 THR THR F . n 
B 2 219 ASN 219 254 254 ASN ASN F . n 
B 2 220 SER 220 255 255 SER SER F . n 
B 2 221 GLU 221 256 256 GLU GLU F . n 
B 2 222 LEU 222 257 257 LEU LEU F . n 
B 2 223 LEU 223 258 258 LEU LEU F . n 
B 2 224 SER 224 259 259 SER SER F . n 
B 2 225 LEU 225 260 260 LEU LEU F . n 
B 2 226 ILE 226 261 261 ILE ILE F . n 
B 2 227 ASN 227 262 262 ASN ASN F . n 
B 2 228 ASP 228 263 263 ASP ASP F . n 
B 2 229 MET 229 264 264 MET MET F . n 
B 2 230 PRO 230 265 265 PRO PRO F . n 
B 2 231 ILE 231 266 266 ILE ILE F . n 
B 2 232 THR 232 267 267 THR THR F . n 
B 2 233 ASN 233 268 268 ASN ASN F . n 
B 2 234 ASP 234 269 269 ASP ASP F . n 
B 2 235 GLN 235 270 270 GLN GLN F . n 
B 2 236 LYS 236 271 271 LYS LYS F . n 
B 2 237 LYS 237 272 272 LYS LYS F . n 
B 2 238 LEU 238 273 273 LEU LEU F . n 
B 2 239 MET 239 274 274 MET MET F . n 
B 2 240 SER 240 275 275 SER SER F . n 
B 2 241 ASN 241 276 276 ASN ASN F . n 
B 2 242 ASN 242 277 277 ASN ASN F . n 
B 2 243 VAL 243 278 278 VAL VAL F . n 
B 2 244 GLN 244 279 279 GLN GLN F . n 
B 2 245 ILE 245 280 280 ILE ILE F . n 
B 2 246 VAL 246 281 281 VAL VAL F . n 
B 2 247 ARG 247 282 282 ARG ARG F . n 
B 2 248 GLN 248 283 283 GLN GLN F . n 
B 2 249 GLN 249 284 284 GLN GLN F . n 
B 2 250 SER 250 285 285 SER SER F . n 
B 2 251 TYR 251 286 286 TYR TYR F . n 
B 2 252 SER 252 287 287 SER SER F . n 
B 2 253 ILE 253 288 288 ILE ILE F . n 
B 2 254 MET 254 289 289 MET MET F . n 
B 2 255 CYS 255 290 290 CYS CYS F . n 
B 2 256 ILE 256 291 291 ILE ILE F . n 
B 2 257 ILE 257 292 292 ILE ILE F . n 
B 2 258 LYS 258 293 293 LYS LYS F . n 
B 2 259 GLU 259 294 294 GLU GLU F . n 
B 2 260 GLU 260 295 295 GLU GLU F . n 
B 2 261 VAL 261 296 296 VAL VAL F . n 
B 2 262 LEU 262 297 297 LEU LEU F . n 
B 2 263 ALA 263 298 298 ALA ALA F . n 
B 2 264 TYR 264 299 299 TYR TYR F . n 
B 2 265 VAL 265 300 300 VAL VAL F . n 
B 2 266 VAL 266 301 301 VAL VAL F . n 
B 2 267 GLN 267 302 302 GLN GLN F . n 
B 2 268 LEU 268 303 303 LEU LEU F . n 
B 2 269 PRO 269 304 304 PRO PRO F . n 
B 2 270 LEU 270 305 305 LEU LEU F . n 
B 2 271 TYR 271 306 306 TYR TYR F . n 
B 2 272 GLY 272 307 307 GLY GLY F . n 
B 2 273 VAL 273 308 308 VAL VAL F . n 
B 2 274 ILE 274 309 309 ILE ILE F . n 
B 2 275 ASP 275 310 310 ASP ASP F . n 
B 2 276 THR 276 311 311 THR THR F . n 
B 2 277 PRO 277 312 312 PRO PRO F . n 
B 2 278 CYS 278 313 313 CYS CYS F . n 
B 2 279 TRP 279 314 314 TRP TRP F . n 
B 2 280 LYS 280 315 315 LYS LYS F . n 
B 2 281 LEU 281 316 316 LEU LEU F . n 
B 2 282 HIS 282 317 317 HIS HIS F . n 
B 2 283 THR 283 318 318 THR THR F . n 
B 2 284 SER 284 319 319 SER SER F . n 
B 2 285 PRO 285 320 320 PRO PRO F . n 
B 2 286 LEU 286 321 321 LEU LEU F . n 
B 2 287 CYS 287 322 322 CYS CYS F . n 
B 2 288 THR 288 323 323 THR THR F . n 
B 2 289 THR 289 324 324 THR THR F . n 
B 2 290 ASN 290 325 325 ASN ASN F . n 
B 2 291 THR 291 326 326 THR THR F . n 
B 2 292 LYS 292 327 327 LYS LYS F . n 
B 2 293 GLU 293 328 328 GLU GLU F . n 
B 2 294 GLY 294 329 329 GLY GLY F . n 
B 2 295 SER 295 330 330 SER SER F . n 
B 2 296 ASN 296 331 331 ASN ASN F . n 
B 2 297 ILE 297 332 332 ILE ILE F . n 
B 2 298 CYS 298 333 333 CYS CYS F . n 
B 2 299 LEU 299 334 334 LEU LEU F . n 
B 2 300 THR 300 335 335 THR THR F . n 
B 2 301 ARG 301 336 336 ARG ARG F . n 
B 2 302 THR 302 337 337 THR THR F . n 
B 2 303 ASP 303 338 338 ASP ASP F . n 
B 2 304 ARG 304 339 339 ARG ARG F . n 
B 2 305 GLY 305 340 340 GLY GLY F . n 
B 2 306 TRP 306 341 341 TRP TRP F . n 
B 2 307 TYR 307 342 342 TYR TYR F . n 
B 2 308 CYS 308 343 343 CYS CYS F . n 
B 2 309 ASP 309 344 344 ASP ASP F . n 
B 2 310 ASN 310 345 345 ASN ASN F . n 
B 2 311 ALA 311 346 346 ALA ALA F . n 
B 2 312 GLY 312 347 347 GLY GLY F . n 
B 2 313 SER 313 348 348 SER SER F . n 
B 2 314 VAL 314 349 349 VAL VAL F . n 
B 2 315 SER 315 350 350 SER SER F . n 
B 2 316 PHE 316 351 351 PHE PHE F . n 
B 2 317 PHE 317 352 352 PHE PHE F . n 
B 2 318 PRO 318 353 353 PRO PRO F . n 
B 2 319 GLN 319 354 354 GLN GLN F . n 
B 2 320 ALA 320 355 355 ALA ALA F . n 
B 2 321 GLU 321 356 356 GLU GLU F . n 
B 2 322 THR 322 357 357 THR THR F . n 
B 2 323 CYS 323 358 358 CYS CYS F . n 
B 2 324 LYS 324 359 359 LYS LYS F . n 
B 2 325 VAL 325 360 360 VAL VAL F . n 
B 2 326 GLN 326 361 361 GLN GLN F . n 
B 2 327 SER 327 362 362 SER SER F . n 
B 2 328 ASN 328 363 363 ASN ASN F . n 
B 2 329 ARG 329 364 364 ARG ARG F . n 
B 2 330 VAL 330 365 365 VAL VAL F . n 
B 2 331 PHE 331 366 366 PHE PHE F . n 
B 2 332 CYS 332 367 367 CYS CYS F . n 
B 2 333 ASP 333 368 368 ASP ASP F . n 
B 2 334 THR 334 369 369 THR THR F . n 
B 2 335 MET 335 370 370 MET MET F . n 
B 2 336 ASN 336 371 371 ASN ASN F . n 
B 2 337 SER 337 372 372 SER SER F . n 
B 2 338 LEU 338 373 373 LEU LEU F . n 
B 2 339 THR 339 374 374 THR THR F . n 
B 2 340 LEU 340 375 375 LEU LEU F . n 
B 2 341 PRO 341 376 376 PRO PRO F . n 
B 2 342 SER 342 377 377 SER SER F . n 
B 2 343 GLU 343 378 378 GLU GLU F . n 
B 2 344 VAL 344 379 379 VAL VAL F . n 
B 2 345 ASN 345 380 380 ASN ASN F . n 
B 2 346 LEU 346 381 381 LEU LEU F . n 
B 2 347 CYS 347 382 382 CYS CYS F . n 
B 2 348 ASN 348 383 383 ASN ASN F . n 
B 2 349 VAL 349 384 384 VAL VAL F . n 
B 2 350 ASP 350 385 385 ASP ASP F . n 
B 2 351 ILE 351 386 386 ILE ILE F . n 
B 2 352 PHE 352 387 387 PHE PHE F . n 
B 2 353 ASN 353 388 388 ASN ASN F . n 
B 2 354 PRO 354 389 389 PRO PRO F . n 
B 2 355 LYS 355 390 390 LYS LYS F . n 
B 2 356 TYR 356 391 391 TYR TYR F . n 
B 2 357 ASP 357 392 392 ASP ASP F . n 
B 2 358 CYS 358 393 393 CYS CYS F . n 
B 2 359 LYS 359 394 394 LYS LYS F . n 
B 2 360 ILE 360 395 395 ILE ILE F . n 
B 2 361 MET 361 396 396 MET MET F . n 
B 2 362 THR 362 397 397 THR THR F . n 
B 2 363 SER 363 398 398 SER SER F . n 
B 2 364 LYS 364 399 399 LYS LYS F . n 
B 2 365 THR 365 400 400 THR THR F . n 
B 2 366 ASP 366 401 401 ASP ASP F . n 
B 2 367 VAL 367 402 402 VAL VAL F . n 
B 2 368 SER 368 403 403 SER SER F . n 
B 2 369 SER 369 404 404 SER SER F . n 
B 2 370 SER 370 405 405 SER SER F . n 
B 2 371 VAL 371 406 406 VAL VAL F . n 
B 2 372 ILE 372 407 407 ILE ILE F . n 
B 2 373 THR 373 408 408 THR THR F . n 
B 2 374 SER 374 409 409 SER SER F . n 
B 2 375 LEU 375 410 410 LEU LEU F . n 
B 2 376 GLY 376 411 411 GLY GLY F . n 
B 2 377 ALA 377 412 412 ALA ALA F . n 
B 2 378 ILE 378 413 413 ILE ILE F . n 
B 2 379 VAL 379 414 414 VAL VAL F . n 
B 2 380 SER 380 415 415 SER SER F . n 
B 2 381 CYS 381 416 416 CYS CYS F . n 
B 2 382 TYR 382 417 417 TYR TYR F . n 
B 2 383 GLY 383 418 418 GLY GLY F . n 
B 2 384 LYS 384 419 419 LYS LYS F . n 
B 2 385 THR 385 420 420 THR THR F . n 
B 2 386 LYS 386 421 421 LYS LYS F . n 
B 2 387 CYS 387 422 422 CYS CYS F . n 
B 2 388 THR 388 423 423 THR THR F . n 
B 2 389 ALA 389 424 424 ALA ALA F . n 
B 2 390 SER 390 425 425 SER SER F . n 
B 2 391 ASN 391 426 426 ASN ASN F . n 
B 2 392 LYS 392 427 427 LYS LYS F . n 
B 2 393 ASN 393 428 428 ASN ASN F . n 
B 2 394 ARG 394 429 429 ARG ARG F . n 
B 2 395 GLY 395 430 430 GLY GLY F . n 
B 2 396 ILE 396 431 431 ILE ILE F . n 
B 2 397 ILE 397 432 432 ILE ILE F . n 
B 2 398 LYS 398 433 433 LYS LYS F . n 
B 2 399 THR 399 434 434 THR THR F . n 
B 2 400 PHE 400 435 435 PHE PHE F . n 
B 2 401 SER 401 436 436 SER SER F . n 
B 2 402 ASN 402 437 437 ASN ASN F . n 
B 2 403 GLY 403 438 438 GLY GLY F . n 
B 2 404 CYS 404 439 439 CYS CYS F . n 
B 2 405 ASP 405 440 440 ASP ASP F . n 
B 2 406 TYR 406 441 441 TYR TYR F . n 
B 2 407 VAL 407 442 442 VAL VAL F . n 
B 2 408 SER 408 443 443 SER SER F . n 
B 2 409 ASN 409 444 444 ASN ASN F . n 
B 2 410 LYS 410 445 445 LYS LYS F . n 
B 2 411 GLY 411 446 446 GLY GLY F . n 
B 2 412 VAL 412 447 447 VAL VAL F . n 
B 2 413 ASP 413 448 448 ASP ASP F . n 
B 2 414 THR 414 449 449 THR THR F . n 
B 2 415 VAL 415 450 450 VAL VAL F . n 
B 2 416 SER 416 451 451 SER SER F . n 
B 2 417 VAL 417 452 452 VAL VAL F . n 
B 2 418 GLY 418 453 453 GLY GLY F . n 
B 2 419 ASN 419 454 454 ASN ASN F . n 
B 2 420 THR 420 455 455 THR THR F . n 
B 2 421 LEU 421 456 456 LEU LEU F . n 
B 2 422 TYR 422 457 457 TYR TYR F . n 
B 2 423 CYS 423 458 458 CYS CYS F . n 
B 2 424 VAL 424 459 459 VAL VAL F . n 
B 2 425 ASN 425 460 460 ASN ASN F . n 
B 2 426 LYS 426 461 461 LYS LYS F . n 
B 2 427 GLN 427 462 462 GLN GLN F . n 
B 2 428 GLU 428 463 463 GLU GLU F . n 
B 2 429 GLY 429 464 464 GLY GLY F . n 
B 2 430 GLN 430 465 465 GLN GLN F . n 
B 2 431 SER 431 466 466 SER SER F . n 
B 2 432 LEU 432 467 467 LEU LEU F . n 
B 2 433 TYR 433 468 468 TYR TYR F . n 
B 2 434 VAL 434 469 469 VAL VAL F . n 
B 2 435 LYS 435 470 470 LYS LYS F . n 
B 2 436 GLY 436 471 471 GLY GLY F . n 
B 2 437 GLU 437 472 472 GLU GLU F . n 
B 2 438 PRO 438 473 473 PRO PRO F . n 
B 2 439 ILE 439 474 474 ILE ILE F . n 
B 2 440 ILE 440 475 475 ILE ILE F . n 
B 2 441 ASN 441 476 476 ASN ASN F . n 
B 2 442 PHE 442 477 477 PHE PHE F . n 
B 2 443 TYR 443 478 478 TYR TYR F . n 
B 2 444 ASP 444 479 479 ASP ASP F . n 
B 2 445 PRO 445 480 480 PRO PRO F . n 
B 2 446 LEU 446 481 481 LEU LEU F . n 
B 2 447 VAL 447 482 482 VAL VAL F . n 
B 2 448 PHE 448 483 483 PHE PHE F . n 
B 2 449 PRO 449 484 484 PRO PRO F . n 
B 2 450 SER 450 485 485 SER SER F . n 
B 2 451 ASN 451 486 486 ASN ASN F . n 
B 2 452 GLN 452 487 487 GLN GLN F . n 
B 2 453 PHE 453 488 488 PHE PHE F . n 
B 2 454 ASP 454 489 489 ASP ASP F . n 
B 2 455 ALA 455 490 490 ALA ALA F . n 
B 2 456 SER 456 491 491 SER SER F . n 
B 2 457 ILE 457 492 492 ILE ILE F . n 
B 2 458 SER 458 493 493 SER SER F . n 
B 2 459 GLN 459 494 494 GLN GLN F . n 
B 2 460 VAL 460 495 495 VAL VAL F . n 
B 2 461 ASN 461 496 496 ASN ASN F . n 
B 2 462 GLU 462 497 497 GLU GLU F . n 
B 2 463 LYS 463 498 498 LYS LYS F . n 
B 2 464 ILE 464 499 499 ILE ILE F . n 
B 2 465 ASN 465 500 500 ASN ASN F . n 
B 2 466 GLN 466 501 501 GLN GLN F . n 
B 2 467 SER 467 502 502 SER SER F . n 
B 2 468 LEU 468 503 503 LEU LEU F . n 
B 2 469 ALA 469 504 504 ALA ALA F . n 
B 2 470 PHE 470 505 505 PHE PHE F . n 
B 2 471 ILE 471 506 506 ILE ILE F . n 
B 2 472 ARG 472 507 507 ARG ARG F . n 
B 2 473 LYS 473 508 508 LYS LYS F . n 
B 2 474 SER 474 509 509 SER SER F . n 
B 2 475 ASP 475 510 ?   ?   ?   F . n 
B 2 476 GLU 476 511 ?   ?   ?   F . n 
B 2 477 LEU 477 512 ?   ?   ?   F . n 
B 2 478 LEU 478 513 ?   ?   ?   F . n 
B 2 479 ALA 479 514 ?   ?   ?   F . n 
B 2 480 SER 480 515 ?   ?   ?   F . n 
B 2 481 GLY 481 516 ?   ?   ?   F . n 
B 2 482 TYR 482 517 ?   ?   ?   F . n 
B 2 483 ILE 483 518 ?   ?   ?   F . n 
B 2 484 PRO 484 519 ?   ?   ?   F . n 
B 2 485 GLU 485 520 ?   ?   ?   F . n 
B 2 486 ALA 486 521 ?   ?   ?   F . n 
B 2 487 PRO 487 522 ?   ?   ?   F . n 
B 2 488 ARG 488 523 ?   ?   ?   F . n 
B 2 489 ASP 489 524 ?   ?   ?   F . n 
B 2 490 GLY 490 525 ?   ?   ?   F . n 
B 2 491 GLN 491 526 ?   ?   ?   F . n 
B 2 492 ALA 492 527 ?   ?   ?   F . n 
B 2 493 TYR 493 528 ?   ?   ?   F . n 
B 2 494 VAL 494 529 ?   ?   ?   F . n 
B 2 495 ARG 495 530 ?   ?   ?   F . n 
B 2 496 LYS 496 531 ?   ?   ?   F . n 
B 2 497 ASP 497 532 ?   ?   ?   F . n 
B 2 498 GLY 498 533 ?   ?   ?   F . n 
B 2 499 GLU 499 534 ?   ?   ?   F . n 
B 2 500 TRP 500 535 ?   ?   ?   F . n 
B 2 501 VAL 501 536 ?   ?   ?   F . n 
B 2 502 LEU 502 537 ?   ?   ?   F . n 
B 2 503 LEU 503 538 ?   ?   ?   F . n 
B 2 504 SER 504 539 ?   ?   ?   F . n 
B 2 505 THR 505 540 ?   ?   ?   F . n 
B 2 506 PHE 506 541 ?   ?   ?   F . n 
B 2 507 LEU 507 542 ?   ?   ?   F . n 
# 
_pdbx_nonpoly_scheme.asym_id         C 
_pdbx_nonpoly_scheme.entity_id       3 
_pdbx_nonpoly_scheme.mon_id          NAG 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     601 
_pdbx_nonpoly_scheme.auth_seq_num    510 
_pdbx_nonpoly_scheme.pdb_mon_id      NAG 
_pdbx_nonpoly_scheme.auth_mon_id     NAG 
_pdbx_nonpoly_scheme.pdb_strand_id   F 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? 1.19.2_4158 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? .           2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? HKL-2000 ? ? ? .           3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHENIX   ? ? ? .           4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  120.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     8W3R 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     100.240 
_cell.length_a_esd                 ? 
_cell.length_b                     100.240 
_cell.length_b_esd                 ? 
_cell.length_c                     588.218 
_cell.length_c_esd                 ? 
_cell.volume                       5118598.415 
_cell.volume_esd                   ? 
_cell.Z_PDB                        18 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         8W3R 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                155 
_symmetry.space_group_name_Hall            
;R 3 2"
;
_symmetry.space_group_name_H-M             'H 3 2' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   8W3R 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             3.38 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          63.63 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '0.1 M MES pH 5.87, 10 %(w/v) PEG 6,000.' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-09-02 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.97 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'SSRL BEAMLINE BL12-1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.97 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   BL12-1 
_diffrn_source.pdbx_synchrotron_site       SSRL 
# 
_reflns.B_iso_Wilson_estimate                          84.78 
_reflns.entry_id                                       8W3R 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              4.02 
_reflns.d_resolution_low                               50.12 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     9477 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           94.75 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                13.2 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          16.9 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.998 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    4.02 
_reflns_shell.d_res_low                                     4.167 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             742 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.878 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  ? 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               109.96 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 8W3R 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            4.02 
_refine.ls_d_res_low                             50.12 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     9470 
_refine.ls_number_reflns_R_free                  424 
_refine.ls_number_reflns_R_work                  9046 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    94.83 
_refine.ls_percent_reflns_R_free                 4.48 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.2516 
_refine.ls_R_factor_R_free                       0.3026 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.2492 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.34 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1100 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 30.3835 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.5233 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       4.02 
_refine_hist.d_res_low                        50.12 
_refine_hist.number_atoms_solvent             0 
_refine_hist.number_atoms_total               5210 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        5196 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         14 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0054 ? 5312 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.0936 ? 7212 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0582 ? 844  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0076 ? 915  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 4.5349 ? 736  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 4.02 4.17  . . 114 2654 85.30 . . . . 0.2689 . . . . . . . . . . . 0.3533 
'X-RAY DIFFRACTION' 4.61 5.80  . . 172 3097 99.48 . . . . 0.2577 . . . . . . . . . . . 0.3027 
'X-RAY DIFFRACTION' 5.80 50.12 . . 138 3295 99.36 . . . . 0.2341 . . . . . . . . . . . 0.2754 
# 
_struct.entry_id                     8W3R 
_struct.title                        
'Crystal structure of prefusion-stabilized RSV F protein UFCR2-iSS-P2-NQ in complex with A4 single-chain fragment variable' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        8W3R 
_struct_keywords.text            'Respiratory syncytial virus, glycoprotein, prefusion vaccine, stabilized, viral protein' 
_struct_keywords.pdbx_keywords   'VIRAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 8W3R 8W3R ? 1 ? 1 
2 PDB 8W3R 8W3R ? 2 ? 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 8W3R A 1 ? 272 ? 8W3R 1  ? 255 ? 1  255 
2 2 8W3R F 1 ? 507 ? 8W3R -3 ? 542 ? -3 542 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 THR A 28  ? TYR A 32  ? THR A 28  TYR A 32  5 ? 5  
HELX_P HELX_P2  AA2 GLU A 62  ? LYS A 65  ? GLU A 61  LYS A 64  5 ? 4  
HELX_P HELX_P3  AA3 ARG A 87  ? THR A 91  ? ARG A 84  THR A 88  5 ? 5  
HELX_P HELX_P4  AA4 TRP A 106 C TYR A 111 H TRP A 100 TYR A 100 5 ? 6  
HELX_P HELX_P5  AA5 ASP B 77  ? SER B 103 ? ASP F 73  SER F 99  1 ? 27 
HELX_P HELX_P6  AA6 ILE B 113 ? HIS B 124 ? ILE F 148 HIS F 159 1 ? 12 
HELX_P HELX_P7  AA7 GLY B 127 ? LEU B 136 ? GLY F 162 LEU F 171 1 ? 10 
HELX_P HELX_P8  AA8 LEU B 160 ? LEU B 168 ? LEU F 195 LEU F 203 1 ? 9  
HELX_P HELX_P9  AA9 LEU B 168 ? ASN B 173 ? LEU F 203 ASN F 208 1 ? 6  
HELX_P HELX_P10 AB1 ASN B 181 ? ASN B 205 ? ASN F 216 ASN F 240 1 ? 25 
HELX_P HELX_P11 AB2 THR B 218 ? ASP B 228 ? THR F 253 ASP F 263 1 ? 11 
HELX_P HELX_P12 AB3 THR B 232 ? ASN B 242 ? THR F 267 ASN F 277 1 ? 11 
HELX_P HELX_P13 AB4 ASN B 242 ? GLN B 249 ? ASN F 277 GLN F 284 1 ? 8  
HELX_P HELX_P14 AB5 GLN B 319 ? GLU B 321 ? GLN F 354 GLU F 356 5 ? 3  
HELX_P HELX_P15 AB6 MET B 335 ? SER B 337 ? MET F 370 SER F 372 5 ? 3  
HELX_P HELX_P16 AB7 PRO B 341 ? ASN B 348 ? PRO F 376 ASN F 383 5 ? 8  
HELX_P HELX_P17 AB8 PRO B 438 ? TYR B 443 ? PRO F 473 TYR F 478 5 ? 6  
HELX_P HELX_P18 AB9 SER B 456 ? LYS B 473 ? SER F 491 LYS F 508 1 ? 18 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1  disulf ?   ? A CYS 22  SG  ? ? ? 1_555 A CYS 96  SG ? ? A CYS 22  A CYS 93  1_555 ? ? ? ? ? ? ? 2.035 ? ?               
disulf2  disulf ?   ? A CYS 162 SG  ? ? ? 1_555 A CYS 230 SG ? ? A CYS 149 A CYS 214 1_555 ? ? ? ? ? ? ? 2.036 ? ?               
disulf3  disulf ?   ? B CYS 41  SG  ? ? ? 1_555 B CYS 404 SG ? ? F CYS 37  F CYS 439 1_555 ? ? ? ? ? ? ? 2.041 ? ?               
disulf4  disulf ?   ? B CYS 73  SG  ? ? ? 1_555 B CYS 177 SG ? ? F CYS 69  F CYS 212 1_555 ? ? ? ? ? ? ? 2.032 ? ?               
disulf5  disulf ?   ? B CYS 114 SG  ? ? ? 1_555 B CYS 423 SG ? ? F CYS 149 F CYS 458 3_455 ? ? ? ? ? ? ? 2.041 ? ?               
disulf6  disulf ?   ? B CYS 120 SG  ? ? ? 1_555 B CYS 255 SG ? ? F CYS 155 F CYS 290 1_555 ? ? ? ? ? ? ? 2.035 ? ?               
disulf7  disulf ?   ? B CYS 278 SG  ? ? ? 1_555 B CYS 308 SG ? ? F CYS 313 F CYS 343 1_555 ? ? ? ? ? ? ? 2.039 ? ?               
disulf8  disulf ?   ? B CYS 287 SG  ? ? ? 1_555 B CYS 298 SG ? ? F CYS 322 F CYS 333 1_555 ? ? ? ? ? ? ? 2.037 ? ?               
disulf9  disulf ?   ? B CYS 323 SG  ? ? ? 1_555 B CYS 332 SG ? ? F CYS 358 F CYS 367 1_555 ? ? ? ? ? ? ? 2.032 ? ?               
disulf10 disulf ?   ? B CYS 347 SG  ? ? ? 1_555 B CYS 358 SG ? ? F CYS 382 F CYS 393 1_555 ? ? ? ? ? ? ? 2.014 ? ?               
disulf11 disulf ?   ? B CYS 381 SG  ? ? ? 1_555 B CYS 387 SG ? ? F CYS 416 F CYS 422 1_555 ? ? ? ? ? ? ? 2.028 ? ?               
covale1  covale one ? B ASN 465 ND2 ? ? ? 1_555 C NAG .   C1 ? ? F ASN 500 F NAG 601 1_555 ? ? ? ? ? ? ? 1.453 ? N-Glycosylation 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1  NAG C .   ? ASN B 465 ? NAG F 601 ? 1_555 ASN F 500 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
2  CYS A 22  ? CYS A 96  ? CYS A 22  ? 1_555 CYS A 93  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
3  CYS A 162 ? CYS A 230 ? CYS A 149 ? 1_555 CYS A 214 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
4  CYS B 41  ? CYS B 404 ? CYS F 37  ? 1_555 CYS F 439 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
5  CYS B 73  ? CYS B 177 ? CYS F 69  ? 1_555 CYS F 212 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
6  CYS B 114 ? CYS B 423 ? CYS F 149 ? 1_555 CYS F 458 ? 3_455 SG SG  .   . .   None            'Disulfide bridge' 
7  CYS B 120 ? CYS B 255 ? CYS F 155 ? 1_555 CYS F 290 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
8  CYS B 278 ? CYS B 308 ? CYS F 313 ? 1_555 CYS F 343 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
9  CYS B 287 ? CYS B 298 ? CYS F 322 ? 1_555 CYS F 333 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
10 CYS B 323 ? CYS B 332 ? CYS F 358 ? 1_555 CYS F 367 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
11 CYS B 347 ? CYS B 358 ? CYS F 382 ? 1_555 CYS F 393 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
12 CYS B 381 ? CYS B 387 ? CYS F 416 ? 1_555 CYS F 422 ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          THR 
_struct_mon_prot_cis.label_seq_id           210 
_struct_mon_prot_cis.label_asym_id          B 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           THR 
_struct_mon_prot_cis.auth_seq_id            245 
_struct_mon_prot_cis.auth_asym_id           F 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    211 
_struct_mon_prot_cis.pdbx_label_asym_id_2   B 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     246 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    F 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       2.32 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 6 ? 
AA3 ? 5 ? 
AA4 ? 4 ? 
AA5 ? 3 ? 
AA6 ? 7 ? 
AA7 ? 5 ? 
AA8 ? 6 ? 
AA9 ? 4 ? 
AB1 ? 3 ? 
AB2 ? 3 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA2 5 6 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA3 4 5 ? anti-parallel 
AA4 1 2 ? parallel      
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? parallel      
AA6 3 4 ? anti-parallel 
AA6 4 5 ? anti-parallel 
AA6 5 6 ? anti-parallel 
AA6 6 7 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? parallel      
AA7 3 4 ? anti-parallel 
AA7 4 5 ? parallel      
AA8 1 2 ? anti-parallel 
AA8 2 3 ? parallel      
AA8 3 4 ? anti-parallel 
AA8 4 5 ? anti-parallel 
AA8 5 6 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLN A 3   ? SER A 7   ? GLN A 3   SER A 7   
AA1 2 SER A 17  ? SER A 25  ? SER A 17  SER A 25  
AA1 3 THR A 78  ? ASN A 84  A THR A 77  ASN A 83  
AA1 4 PHE A 68  ? ASP A 73  ? PHE A 67  ASP A 72  
AA2 1 GLY A 10  ? LEU A 11  ? GLY A 10  LEU A 11  
AA2 2 THR A 120 ? VAL A 123 ? THR A 107 VAL A 110 
AA2 3 ALA A 92  ? SER A 99  ? ALA A 89  SER A 96  
AA2 4 ALA A 33  ? GLN A 39  ? ALA A 33  GLN A 39  
AA2 5 LEU A 45  ? ILE A 51  ? LEU A 45  ILE A 51  
AA2 6 GLN A 58  ? TYR A 60  ? GLN A 57  TYR A 59  
AA3 1 SER A 149 ? GLY A 152 ? SER A 136 GLY A 139 
AA3 2 THR A 245 ? VAL A 249 ? THR A 228 VAL A 232 
AA3 3 ASP A 227 ? TYR A 233 ? ASP A 211 TYR A 217 
AA3 4 VAL A 175 ? GLN A 180 ? VAL A 159 GLN A 164 
AA3 5 PRO A 186 ? ILE A 190 ? PRO A 170 ILE A 174 
AA4 1 SER A 149 ? GLY A 152 ? SER A 136 GLY A 139 
AA4 2 THR A 245 ? VAL A 249 ? THR A 228 VAL A 232 
AA4 3 ASP A 227 ? TYR A 233 ? ASP A 211 TYR A 217 
AA4 4 LEU A 239 ? PHE A 241 ? LEU A 222 PHE A 224 
AA5 1 SER A 157 ? THR A 163 ? SER A 144 THR A 150 
AA5 2 THR A 212 ? SER A 218 ? THR A 196 SER A 202 
AA5 3 SER A 205 ? SER A 209 ? SER A 189 SER A 193 
AA6 1 CYS B 323 ? GLN B 326 ? CYS F 358 GLN F 361 
AA6 2 ARG B 329 ? ASP B 333 ? ARG F 364 ASP F 368 
AA6 3 SER B 42  ? ARG B 53  ? SER F 38  ARG F 49  
AA6 4 VAL B 273 ? THR B 283 ? VAL F 308 THR F 318 
AA6 5 GLY B 305 ? ASN B 310 ? GLY F 340 ASN F 345 
AA6 6 SER B 313 ? PHE B 317 ? SER F 348 PHE F 352 
AA6 7 LEU B 338 ? LEU B 340 ? LEU F 373 LEU F 375 
AA7 1 CYS B 323 ? GLN B 326 ? CYS F 358 GLN F 361 
AA7 2 ARG B 329 ? ASP B 333 ? ARG F 364 ASP F 368 
AA7 3 SER B 42  ? ARG B 53  ? SER F 38  ARG F 49  
AA7 4 THR B 33  ? TYR B 37  ? THR F 29  TYR F 33  
AA7 5 GLN B 430 ? VAL B 434 ? GLN F 465 VAL F 469 
AA8 1 LYS B 141 ? SER B 145 ? LYS F 176 SER F 180 
AA8 2 SER B 151 ? ASP B 159 ? SER F 186 ASP F 194 
AA8 3 GLY B 55  ? GLU B 64  ? GLY F 51  GLU F 60  
AA8 4 VAL B 261 ? LEU B 270 ? VAL F 296 LEU F 305 
AA8 5 TYR B 251 ? ILE B 257 ? TYR F 286 ILE F 292 
AA8 6 VAL B 208 ? THR B 209 ? VAL F 243 THR F 244 
AA9 1 LEU B 286 ? CYS B 287 ? LEU F 321 CYS F 322 
AA9 2 CYS B 298 ? ARG B 301 ? CYS F 333 ARG F 336 
AA9 3 ILE B 360 ? SER B 363 ? ILE F 395 SER F 398 
AA9 4 ASP B 454 ? ALA B 455 ? ASP F 489 ALA F 490 
AB1 1 SER B 369 ? THR B 373 ? SER F 404 THR F 408 
AB1 2 GLY B 376 ? CYS B 381 ? GLY F 411 CYS F 416 
AB1 3 GLY B 403 ? SER B 408 ? GLY F 438 SER F 443 
AB2 1 CYS B 387 ? THR B 388 ? CYS F 422 THR F 423 
AB2 2 THR B 414 ? VAL B 417 ? THR F 449 VAL F 452 
AB2 3 THR B 420 ? CYS B 423 ? THR F 455 CYS F 458 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N GLN A 3   ? N GLN A 3   O SER A 25  ? O SER A 25  
AA1 2 3 N LEU A 18  ? N LEU A 18  O VAL A 83  ? O VAL A 82  
AA1 3 4 O LEU A 80  ? O LEU A 79  N SER A 71  ? N SER A 70  
AA2 1 2 N GLY A 10  ? N GLY A 10  O VAL A 123 ? O VAL A 110 
AA2 2 3 O THR A 120 ? O THR A 107 N TYR A 94  ? N TYR A 91  
AA2 3 4 O TYR A 95  ? O TYR A 92  N VAL A 37  ? N VAL A 37  
AA2 4 5 N ARG A 38  ? N ARG A 38  O GLU A 46  ? O GLU A 46  
AA2 5 6 N SER A 50  ? N SER A 50  O TYR A 59  ? O TYR A 58  
AA3 1 2 N GLY A 152 ? N GLY A 139 O THR A 248 ? O THR A 231 
AA3 2 3 O THR A 245 ? O THR A 228 N TYR A 228 ? N TYR A 212 
AA3 3 4 O SER A 231 ? O SER A 215 N SER A 176 ? N SER A 160 
AA3 4 5 N GLN A 179 ? N GLN A 163 O LYS A 187 ? O LYS A 171 
AA4 1 2 N GLY A 152 ? N GLY A 139 O THR A 248 ? O THR A 231 
AA4 2 3 O THR A 245 ? O THR A 228 N TYR A 228 ? N TYR A 212 
AA4 3 4 N SER A 232 ? N SER A 216 O ILE A 240 ? O ILE A 223 
AA5 1 2 N CYS A 162 ? N CYS A 149 O ALA A 213 ? O ALA A 197 
AA5 2 3 O THR A 216 ? O THR A 200 N SER A 205 ? N SER A 189 
AA6 1 2 N LYS B 324 ? N LYS F 359 O PHE B 331 ? O PHE F 366 
AA6 2 3 O CYS B 332 ? O CYS F 367 N ARG B 53  ? N ARG F 49  
AA6 3 4 N GLY B 50  ? N GLY F 46  O THR B 276 ? O THR F 311 
AA6 4 5 N TRP B 279 ? N TRP F 314 O TYR B 307 ? O TYR F 342 
AA6 5 6 N CYS B 308 ? N CYS F 343 O SER B 315 ? O SER F 350 
AA6 6 7 N PHE B 316 ? N PHE F 351 O LEU B 338 ? O LEU F 373 
AA7 1 2 N LYS B 324 ? N LYS F 359 O PHE B 331 ? O PHE F 366 
AA7 2 3 O CYS B 332 ? O CYS F 367 N ARG B 53  ? N ARG F 49  
AA7 3 4 O SER B 42  ? O SER F 38  N TYR B 37  ? N TYR F 33  
AA7 4 5 N PHE B 36  ? N PHE F 32  O VAL B 434 ? O VAL F 469 
AA8 1 2 N ALA B 142 ? N ALA F 177 O THR B 154 ? O THR F 189 
AA8 2 3 O SER B 155 ? O SER F 190 N THR B 62  ? N THR F 58  
AA8 3 4 N ILE B 61  ? N ILE F 57  O TYR B 264 ? O TYR F 299 
AA8 4 5 O GLN B 267 ? O GLN F 302 N TYR B 251 ? N TYR F 286 
AA8 5 6 O SER B 252 ? O SER F 287 N THR B 209 ? N THR F 244 
AA9 1 2 N LEU B 286 ? N LEU F 321 O LEU B 299 ? O LEU F 334 
AA9 2 3 N CYS B 298 ? N CYS F 333 O SER B 363 ? O SER F 398 
AA9 3 4 N ILE B 360 ? N ILE F 395 O ALA B 455 ? O ALA F 490 
AB1 1 2 N SER B 369 ? N SER F 404 O SER B 380 ? O SER F 415 
AB1 2 3 N CYS B 381 ? N CYS F 416 O GLY B 403 ? O GLY F 438 
AB2 1 2 N THR B 388 ? N THR F 423 O SER B 416 ? O SER F 451 
AB2 2 3 N VAL B 415 ? N VAL F 450 O TYR B 422 ? O TYR F 457 
# 
_pdbx_entry_details.entry_id                   8W3R 
_pdbx_entry_details.has_ligand_of_interest     N 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_symm_contact.id                1 
_pdbx_validate_symm_contact.PDB_model_num     1 
_pdbx_validate_symm_contact.auth_atom_id_1    CB 
_pdbx_validate_symm_contact.auth_asym_id_1    F 
_pdbx_validate_symm_contact.auth_comp_id_1    CYS 
_pdbx_validate_symm_contact.auth_seq_id_1     149 
_pdbx_validate_symm_contact.PDB_ins_code_1    ? 
_pdbx_validate_symm_contact.label_alt_id_1    ? 
_pdbx_validate_symm_contact.site_symmetry_1   1_555 
_pdbx_validate_symm_contact.auth_atom_id_2    SG 
_pdbx_validate_symm_contact.auth_asym_id_2    F 
_pdbx_validate_symm_contact.auth_comp_id_2    CYS 
_pdbx_validate_symm_contact.auth_seq_id_2     458 
_pdbx_validate_symm_contact.PDB_ins_code_2    ? 
_pdbx_validate_symm_contact.label_alt_id_2    ? 
_pdbx_validate_symm_contact.site_symmetry_2   3_455 
_pdbx_validate_symm_contact.dist              1.72 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 GLN A 39  ? ? -160.40 114.85  
2  1 LEU A 48  ? ? -128.45 -72.47  
3  1 HIS A 100 ? ? 56.38   13.49   
4  1 PHE A 100 G ? -146.03 53.27   
5  1 ALA A 135 ? ? -122.08 -51.85  
6  1 SER A 153 ? ? 66.59   -61.88  
7  1 VAL A 153 C ? 67.84   -55.67  
8  1 PRO A 166 ? ? -55.28  108.23  
9  1 ASP A 176 ? ? 58.15   -104.92 
10 1 VAL A 177 ? ? -133.36 -30.09  
11 1 SER A 193 ? ? -151.13 89.21   
12 1 SER A 219 ? ? 73.38   -17.92  
13 1 LYS F 65  ? ? -114.74 74.97   
14 1 LYS F 68  ? ? -36.10  127.16  
15 1 THR F 72  ? ? -142.76 -50.27  
16 1 THR F 100 ? ? -111.36 50.10   
17 1 LEU F 171 ? ? -92.41  36.54   
18 1 CYS F 290 ? ? -95.04  -102.91 
19 1 SER F 362 ? ? 49.42   -126.45 
20 1 ASN F 371 ? ? -118.19 66.85   
21 1 PHE F 488 ? ? 63.24   -132.94 
# 
_pdbx_validate_main_chain_plane.id                       1 
_pdbx_validate_main_chain_plane.PDB_model_num            1 
_pdbx_validate_main_chain_plane.auth_comp_id             THR 
_pdbx_validate_main_chain_plane.auth_asym_id             F 
_pdbx_validate_main_chain_plane.auth_seq_id              408 
_pdbx_validate_main_chain_plane.PDB_ins_code             ? 
_pdbx_validate_main_chain_plane.label_alt_id             ? 
_pdbx_validate_main_chain_plane.improper_torsion_angle   -11.83 
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1  x,y,z                  
2  -y,x-y,z               
3  -x+y,-x,z              
4  x-y,-y,-z              
5  -x,-x+y,-z             
6  y,x,-z                 
7  x+1/3,y+2/3,z+2/3      
8  -y+1/3,x-y+2/3,z+2/3   
9  -x+y+1/3,-x+2/3,z+2/3  
10 x-y+1/3,-y+2/3,-z+2/3  
11 -x+1/3,-x+y+2/3,-z+2/3 
12 y+1/3,x+2/3,-z+2/3     
13 x+2/3,y+1/3,z+1/3      
14 -y+2/3,x-y+1/3,z+1/3   
15 -x+y+2/3,-x+1/3,z+1/3  
16 x-y+2/3,-y+1/3,-z+1/3  
17 -x+2/3,-x+y+1/3,-z+1/3 
18 y+2/3,x+1/3,-z+1/3     
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A GLY 114 ? A GLY 127 
2  1 Y 1 A GLY 115 ? A GLY 128 
3  1 Y 1 A GLY 116 ? A GLY 129 
4  1 Y 1 A SER 117 ? A SER 130 
5  1 Y 1 A GLY 118 ? A GLY 131 
6  1 Y 1 A GLY 119 ? A GLY 132 
7  1 Y 1 A GLY 120 ? A GLY 133 
8  1 Y 1 A GLY 121 ? A GLY 134 
9  1 Y 1 A SER 122 ? A SER 135 
10 1 Y 1 A GLY 123 ? A GLY 136 
11 1 Y 1 A GLY 124 ? A GLY 137 
12 1 Y 1 A GLY 125 ? A GLY 138 
13 1 Y 1 A GLY 126 ? A GLY 139 
14 1 Y 1 A SER 127 ? A SER 140 
15 1 Y 1 A THR 234 ? A THR 251 
16 1 Y 1 A SER 235 ? A SER 252 
17 1 Y 1 A GLY 236 ? A GLY 253 
18 1 Y 1 A PRO 237 ? A PRO 254 
19 1 Y 1 A GLY 238 ? A GLY 255 
20 1 Y 1 A GLY 239 ? A GLY 256 
21 1 Y 1 A PRO 240 ? A PRO 257 
22 1 Y 1 A GLU 241 ? A GLU 258 
23 1 Y 1 A PRO 242 ? A PRO 259 
24 1 Y 1 A LYS 243 ? A LYS 260 
25 1 Y 1 A SER 244 ? A SER 261 
26 1 Y 1 A SER 245 ? A SER 262 
27 1 Y 1 A ASP 246 ? A ASP 263 
28 1 Y 1 A LYS 247 ? A LYS 264 
29 1 Y 1 A GLY 248 ? A GLY 265 
30 1 Y 1 A SER 249 ? A SER 266 
31 1 Y 1 A HIS 250 ? A HIS 267 
32 1 Y 1 A HIS 251 ? A HIS 268 
33 1 Y 1 A HIS 252 ? A HIS 269 
34 1 Y 1 A HIS 253 ? A HIS 270 
35 1 Y 1 A HIS 254 ? A HIS 271 
36 1 Y 1 A HIS 255 ? A HIS 272 
37 1 Y 1 F MET -3  ? B MET 1   
38 1 Y 1 F GLY -2  ? B GLY 2   
39 1 Y 1 F ILE -1  ? B ILE 3   
40 1 Y 1 F LEU 0   ? B LEU 4   
41 1 Y 1 F PRO 1   ? B PRO 5   
42 1 Y 1 F SER 2   ? B SER 6   
43 1 Y 1 F PRO 3   ? B PRO 7   
44 1 Y 1 F GLY 4   ? B GLY 8   
45 1 Y 1 F MET 5   ? B MET 9   
46 1 Y 1 F PRO 6   ? B PRO 10  
47 1 Y 1 F ALA 7   ? B ALA 11  
48 1 Y 1 F LEU 8   ? B LEU 12  
49 1 Y 1 F LEU 9   ? B LEU 13  
50 1 Y 1 F SER 10  ? B SER 14  
51 1 Y 1 F LEU 11  ? B LEU 15  
52 1 Y 1 F VAL 12  ? B VAL 16  
53 1 Y 1 F SER 13  ? B SER 17  
54 1 Y 1 F LEU 14  ? B LEU 18  
55 1 Y 1 F LEU 15  ? B LEU 19  
56 1 Y 1 F SER 16  ? B SER 20  
57 1 Y 1 F VAL 17  ? B VAL 21  
58 1 Y 1 F LEU 18  ? B LEU 22  
59 1 Y 1 F LEU 19  ? B LEU 23  
60 1 Y 1 F MET 20  ? B MET 24  
61 1 Y 1 F GLY 21  ? B GLY 25  
62 1 Y 1 F CYS 22  ? B CYS 26  
63 1 Y 1 F VAL 23  ? B VAL 27  
64 1 Y 1 F ALA 24  ? B ALA 28  
65 1 Y 1 F GLU 25  ? B GLU 29  
66 1 Y 1 F ASP 510 ? B ASP 475 
67 1 Y 1 F GLU 511 ? B GLU 476 
68 1 Y 1 F LEU 512 ? B LEU 477 
69 1 Y 1 F LEU 513 ? B LEU 478 
70 1 Y 1 F ALA 514 ? B ALA 479 
71 1 Y 1 F SER 515 ? B SER 480 
72 1 Y 1 F GLY 516 ? B GLY 481 
73 1 Y 1 F TYR 517 ? B TYR 482 
74 1 Y 1 F ILE 518 ? B ILE 483 
75 1 Y 1 F PRO 519 ? B PRO 484 
76 1 Y 1 F GLU 520 ? B GLU 485 
77 1 Y 1 F ALA 521 ? B ALA 486 
78 1 Y 1 F PRO 522 ? B PRO 487 
79 1 Y 1 F ARG 523 ? B ARG 488 
80 1 Y 1 F ASP 524 ? B ASP 489 
81 1 Y 1 F GLY 525 ? B GLY 490 
82 1 Y 1 F GLN 526 ? B GLN 491 
83 1 Y 1 F ALA 527 ? B ALA 492 
84 1 Y 1 F TYR 528 ? B TYR 493 
85 1 Y 1 F VAL 529 ? B VAL 494 
86 1 Y 1 F ARG 530 ? B ARG 495 
87 1 Y 1 F LYS 531 ? B LYS 496 
88 1 Y 1 F ASP 532 ? B ASP 497 
89 1 Y 1 F GLY 533 ? B GLY 498 
90 1 Y 1 F GLU 534 ? B GLU 499 
91 1 Y 1 F TRP 535 ? B TRP 500 
92 1 Y 1 F VAL 536 ? B VAL 501 
93 1 Y 1 F LEU 537 ? B LEU 502 
94 1 Y 1 F LEU 538 ? B LEU 503 
95 1 Y 1 F SER 539 ? B SER 504 
96 1 Y 1 F THR 540 ? B THR 505 
97 1 Y 1 F PHE 541 ? B PHE 506 
98 1 Y 1 F LEU 542 ? B LEU 507 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
NAG C1   C N R 247 
NAG C2   C N R 248 
NAG C3   C N R 249 
NAG C4   C N S 250 
NAG C5   C N R 251 
NAG C6   C N N 252 
NAG C7   C N N 253 
NAG C8   C N N 254 
NAG N2   N N N 255 
NAG O1   O N N 256 
NAG O3   O N N 257 
NAG O4   O N N 258 
NAG O5   O N N 259 
NAG O6   O N N 260 
NAG O7   O N N 261 
NAG H1   H N N 262 
NAG H2   H N N 263 
NAG H3   H N N 264 
NAG H4   H N N 265 
NAG H5   H N N 266 
NAG H61  H N N 267 
NAG H62  H N N 268 
NAG H81  H N N 269 
NAG H82  H N N 270 
NAG H83  H N N 271 
NAG HN2  H N N 272 
NAG HO1  H N N 273 
NAG HO3  H N N 274 
NAG HO4  H N N 275 
NAG HO6  H N N 276 
PHE N    N N N 277 
PHE CA   C N S 278 
PHE C    C N N 279 
PHE O    O N N 280 
PHE CB   C N N 281 
PHE CG   C Y N 282 
PHE CD1  C Y N 283 
PHE CD2  C Y N 284 
PHE CE1  C Y N 285 
PHE CE2  C Y N 286 
PHE CZ   C Y N 287 
PHE OXT  O N N 288 
PHE H    H N N 289 
PHE H2   H N N 290 
PHE HA   H N N 291 
PHE HB2  H N N 292 
PHE HB3  H N N 293 
PHE HD1  H N N 294 
PHE HD2  H N N 295 
PHE HE1  H N N 296 
PHE HE2  H N N 297 
PHE HZ   H N N 298 
PHE HXT  H N N 299 
PRO N    N N N 300 
PRO CA   C N S 301 
PRO C    C N N 302 
PRO O    O N N 303 
PRO CB   C N N 304 
PRO CG   C N N 305 
PRO CD   C N N 306 
PRO OXT  O N N 307 
PRO H    H N N 308 
PRO HA   H N N 309 
PRO HB2  H N N 310 
PRO HB3  H N N 311 
PRO HG2  H N N 312 
PRO HG3  H N N 313 
PRO HD2  H N N 314 
PRO HD3  H N N 315 
PRO HXT  H N N 316 
SER N    N N N 317 
SER CA   C N S 318 
SER C    C N N 319 
SER O    O N N 320 
SER CB   C N N 321 
SER OG   O N N 322 
SER OXT  O N N 323 
SER H    H N N 324 
SER H2   H N N 325 
SER HA   H N N 326 
SER HB2  H N N 327 
SER HB3  H N N 328 
SER HG   H N N 329 
SER HXT  H N N 330 
THR N    N N N 331 
THR CA   C N S 332 
THR C    C N N 333 
THR O    O N N 334 
THR CB   C N R 335 
THR OG1  O N N 336 
THR CG2  C N N 337 
THR OXT  O N N 338 
THR H    H N N 339 
THR H2   H N N 340 
THR HA   H N N 341 
THR HB   H N N 342 
THR HG1  H N N 343 
THR HG21 H N N 344 
THR HG22 H N N 345 
THR HG23 H N N 346 
THR HXT  H N N 347 
TRP N    N N N 348 
TRP CA   C N S 349 
TRP C    C N N 350 
TRP O    O N N 351 
TRP CB   C N N 352 
TRP CG   C Y N 353 
TRP CD1  C Y N 354 
TRP CD2  C Y N 355 
TRP NE1  N Y N 356 
TRP CE2  C Y N 357 
TRP CE3  C Y N 358 
TRP CZ2  C Y N 359 
TRP CZ3  C Y N 360 
TRP CH2  C Y N 361 
TRP OXT  O N N 362 
TRP H    H N N 363 
TRP H2   H N N 364 
TRP HA   H N N 365 
TRP HB2  H N N 366 
TRP HB3  H N N 367 
TRP HD1  H N N 368 
TRP HE1  H N N 369 
TRP HE3  H N N 370 
TRP HZ2  H N N 371 
TRP HZ3  H N N 372 
TRP HH2  H N N 373 
TRP HXT  H N N 374 
TYR N    N N N 375 
TYR CA   C N S 376 
TYR C    C N N 377 
TYR O    O N N 378 
TYR CB   C N N 379 
TYR CG   C Y N 380 
TYR CD1  C Y N 381 
TYR CD2  C Y N 382 
TYR CE1  C Y N 383 
TYR CE2  C Y N 384 
TYR CZ   C Y N 385 
TYR OH   O N N 386 
TYR OXT  O N N 387 
TYR H    H N N 388 
TYR H2   H N N 389 
TYR HA   H N N 390 
TYR HB2  H N N 391 
TYR HB3  H N N 392 
TYR HD1  H N N 393 
TYR HD2  H N N 394 
TYR HE1  H N N 395 
TYR HE2  H N N 396 
TYR HH   H N N 397 
TYR HXT  H N N 398 
VAL N    N N N 399 
VAL CA   C N S 400 
VAL C    C N N 401 
VAL O    O N N 402 
VAL CB   C N N 403 
VAL CG1  C N N 404 
VAL CG2  C N N 405 
VAL OXT  O N N 406 
VAL H    H N N 407 
VAL H2   H N N 408 
VAL HA   H N N 409 
VAL HB   H N N 410 
VAL HG11 H N N 411 
VAL HG12 H N N 412 
VAL HG13 H N N 413 
VAL HG21 H N N 414 
VAL HG22 H N N 415 
VAL HG23 H N N 416 
VAL HXT  H N N 417 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
NAG C1  C2   sing N N 235 
NAG C1  O1   sing N N 236 
NAG C1  O5   sing N N 237 
NAG C1  H1   sing N N 238 
NAG C2  C3   sing N N 239 
NAG C2  N2   sing N N 240 
NAG C2  H2   sing N N 241 
NAG C3  C4   sing N N 242 
NAG C3  O3   sing N N 243 
NAG C3  H3   sing N N 244 
NAG C4  C5   sing N N 245 
NAG C4  O4   sing N N 246 
NAG C4  H4   sing N N 247 
NAG C5  C6   sing N N 248 
NAG C5  O5   sing N N 249 
NAG C5  H5   sing N N 250 
NAG C6  O6   sing N N 251 
NAG C6  H61  sing N N 252 
NAG C6  H62  sing N N 253 
NAG C7  C8   sing N N 254 
NAG C7  N2   sing N N 255 
NAG C7  O7   doub N N 256 
NAG C8  H81  sing N N 257 
NAG C8  H82  sing N N 258 
NAG C8  H83  sing N N 259 
NAG N2  HN2  sing N N 260 
NAG O1  HO1  sing N N 261 
NAG O3  HO3  sing N N 262 
NAG O4  HO4  sing N N 263 
NAG O6  HO6  sing N N 264 
PHE N   CA   sing N N 265 
PHE N   H    sing N N 266 
PHE N   H2   sing N N 267 
PHE CA  C    sing N N 268 
PHE CA  CB   sing N N 269 
PHE CA  HA   sing N N 270 
PHE C   O    doub N N 271 
PHE C   OXT  sing N N 272 
PHE CB  CG   sing N N 273 
PHE CB  HB2  sing N N 274 
PHE CB  HB3  sing N N 275 
PHE CG  CD1  doub Y N 276 
PHE CG  CD2  sing Y N 277 
PHE CD1 CE1  sing Y N 278 
PHE CD1 HD1  sing N N 279 
PHE CD2 CE2  doub Y N 280 
PHE CD2 HD2  sing N N 281 
PHE CE1 CZ   doub Y N 282 
PHE CE1 HE1  sing N N 283 
PHE CE2 CZ   sing Y N 284 
PHE CE2 HE2  sing N N 285 
PHE CZ  HZ   sing N N 286 
PHE OXT HXT  sing N N 287 
PRO N   CA   sing N N 288 
PRO N   CD   sing N N 289 
PRO N   H    sing N N 290 
PRO CA  C    sing N N 291 
PRO CA  CB   sing N N 292 
PRO CA  HA   sing N N 293 
PRO C   O    doub N N 294 
PRO C   OXT  sing N N 295 
PRO CB  CG   sing N N 296 
PRO CB  HB2  sing N N 297 
PRO CB  HB3  sing N N 298 
PRO CG  CD   sing N N 299 
PRO CG  HG2  sing N N 300 
PRO CG  HG3  sing N N 301 
PRO CD  HD2  sing N N 302 
PRO CD  HD3  sing N N 303 
PRO OXT HXT  sing N N 304 
SER N   CA   sing N N 305 
SER N   H    sing N N 306 
SER N   H2   sing N N 307 
SER CA  C    sing N N 308 
SER CA  CB   sing N N 309 
SER CA  HA   sing N N 310 
SER C   O    doub N N 311 
SER C   OXT  sing N N 312 
SER CB  OG   sing N N 313 
SER CB  HB2  sing N N 314 
SER CB  HB3  sing N N 315 
SER OG  HG   sing N N 316 
SER OXT HXT  sing N N 317 
THR N   CA   sing N N 318 
THR N   H    sing N N 319 
THR N   H2   sing N N 320 
THR CA  C    sing N N 321 
THR CA  CB   sing N N 322 
THR CA  HA   sing N N 323 
THR C   O    doub N N 324 
THR C   OXT  sing N N 325 
THR CB  OG1  sing N N 326 
THR CB  CG2  sing N N 327 
THR CB  HB   sing N N 328 
THR OG1 HG1  sing N N 329 
THR CG2 HG21 sing N N 330 
THR CG2 HG22 sing N N 331 
THR CG2 HG23 sing N N 332 
THR OXT HXT  sing N N 333 
TRP N   CA   sing N N 334 
TRP N   H    sing N N 335 
TRP N   H2   sing N N 336 
TRP CA  C    sing N N 337 
TRP CA  CB   sing N N 338 
TRP CA  HA   sing N N 339 
TRP C   O    doub N N 340 
TRP C   OXT  sing N N 341 
TRP CB  CG   sing N N 342 
TRP CB  HB2  sing N N 343 
TRP CB  HB3  sing N N 344 
TRP CG  CD1  doub Y N 345 
TRP CG  CD2  sing Y N 346 
TRP CD1 NE1  sing Y N 347 
TRP CD1 HD1  sing N N 348 
TRP CD2 CE2  doub Y N 349 
TRP CD2 CE3  sing Y N 350 
TRP NE1 CE2  sing Y N 351 
TRP NE1 HE1  sing N N 352 
TRP CE2 CZ2  sing Y N 353 
TRP CE3 CZ3  doub Y N 354 
TRP CE3 HE3  sing N N 355 
TRP CZ2 CH2  doub Y N 356 
TRP CZ2 HZ2  sing N N 357 
TRP CZ3 CH2  sing Y N 358 
TRP CZ3 HZ3  sing N N 359 
TRP CH2 HH2  sing N N 360 
TRP OXT HXT  sing N N 361 
TYR N   CA   sing N N 362 
TYR N   H    sing N N 363 
TYR N   H2   sing N N 364 
TYR CA  C    sing N N 365 
TYR CA  CB   sing N N 366 
TYR CA  HA   sing N N 367 
TYR C   O    doub N N 368 
TYR C   OXT  sing N N 369 
TYR CB  CG   sing N N 370 
TYR CB  HB2  sing N N 371 
TYR CB  HB3  sing N N 372 
TYR CG  CD1  doub Y N 373 
TYR CG  CD2  sing Y N 374 
TYR CD1 CE1  sing Y N 375 
TYR CD1 HD1  sing N N 376 
TYR CD2 CE2  doub Y N 377 
TYR CD2 HD2  sing N N 378 
TYR CE1 CZ   doub Y N 379 
TYR CE1 HE1  sing N N 380 
TYR CE2 CZ   sing Y N 381 
TYR CE2 HE2  sing N N 382 
TYR CZ  OH   sing N N 383 
TYR OH  HH   sing N N 384 
TYR OXT HXT  sing N N 385 
VAL N   CA   sing N N 386 
VAL N   H    sing N N 387 
VAL N   H2   sing N N 388 
VAL CA  C    sing N N 389 
VAL CA  CB   sing N N 390 
VAL CA  HA   sing N N 391 
VAL C   O    doub N N 392 
VAL C   OXT  sing N N 393 
VAL CB  CG1  sing N N 394 
VAL CB  CG2  sing N N 395 
VAL CB  HB   sing N N 396 
VAL CG1 HG11 sing N N 397 
VAL CG1 HG12 sing N N 398 
VAL CG1 HG13 sing N N 399 
VAL CG2 HG21 sing N N 400 
VAL CG2 HG22 sing N N 401 
VAL CG2 HG23 sing N N 402 
VAL OXT HXT  sing N N 403 
# 
_pdbx_audit_support.funding_organization   'Other private' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   5K6I 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'R 3 2 :H' 
_space_group.name_Hall        
;R 3 2"
;
_space_group.IT_number        155 
_space_group.crystal_system   trigonal 
_space_group.id               1 
# 
_atom_sites.entry_id                    8W3R 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.009976 
_atom_sites.fract_transf_matrix[1][2]   0.005760 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.011519 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.001700 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 5.96793  ? ? ? 14.89577 ? ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 6.96715  ? ? ? 11.43723 ? ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 7.96527  ? ? ? 9.05267  ? ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 15.91112 ? ? ? 10.84690 ? ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . GLU A 1 1   ? -73.29703 -19.10474 67.83430  1.000 105.21438 ? 1   GLU A N   1 
ATOM   2    C CA  . GLU A 1 1   ? -72.04944 -19.85688 67.74089  1.000 115.36095 ? 1   GLU A CA  1 
ATOM   3    C C   . GLU A 1 1   ? -70.86893 -18.96510 67.38596  1.000 115.85603 ? 1   GLU A C   1 
ATOM   4    O O   . GLU A 1 1   ? -70.10788 -19.25233 66.46186  1.000 115.03123 ? 1   GLU A O   1 
ATOM   5    C CB  . GLU A 1 1   ? -72.17822 -20.98648 66.71890  1.000 124.24008 ? 1   GLU A CB  1 
ATOM   6    C CG  . GLU A 1 1   ? -71.27634 -22.18291 67.00362  1.000 124.33376 ? 1   GLU A CG  1 
ATOM   7    C CD  . GLU A 1 1   ? -70.19673 -22.35791 65.94364  1.000 127.51839 ? 1   GLU A CD  1 
ATOM   8    O OE1 . GLU A 1 1   ? -70.24621 -21.63727 64.92229  1.000 124.46009 ? 1   GLU A OE1 1 
ATOM   9    O OE2 . GLU A 1 1   ? -69.29763 -23.20504 66.12952  1.000 125.35127 ? 1   GLU A OE2 1 
ATOM   10   N N   . VAL A 1 2   ? -70.72164 -17.87087 68.12505  1.000 110.52655 ? 2   VAL A N   1 
ATOM   11   C CA  . VAL A 1 2   ? -69.53053 -17.03648 68.04869  1.000 101.27869 ? 2   VAL A CA  1 
ATOM   12   C C   . VAL A 1 2   ? -68.58154 -17.55616 69.12164  1.000 100.81025 ? 2   VAL A C   1 
ATOM   13   O O   . VAL A 1 2   ? -68.72555 -17.23888 70.30247  1.000 106.19100 ? 2   VAL A O   1 
ATOM   14   C CB  . VAL A 1 2   ? -69.86099 -15.55855 68.24073  1.000 96.72952  ? 2   VAL A CB  1 
ATOM   15   C CG1 . VAL A 1 2   ? -68.70369 -14.71569 67.76322  1.000 92.12627  ? 2   VAL A CG1 1 
ATOM   16   C CG2 . VAL A 1 2   ? -71.13399 -15.20580 67.48882  1.000 98.51710  ? 2   VAL A CG2 1 
ATOM   17   N N   . GLN A 1 3   ? -67.60549 -18.36021 68.71055  1.000 96.56923  ? 3   GLN A N   1 
ATOM   18   C CA  . GLN A 1 3   ? -66.86161 -19.20786 69.63455  1.000 98.63906  ? 3   GLN A CA  1 
ATOM   19   C C   . GLN A 1 3   ? -65.39299 -18.80309 69.68122  1.000 91.10986  ? 3   GLN A C   1 
ATOM   20   O O   . GLN A 1 3   ? -64.71736 -18.76829 68.64467  1.000 82.97237  ? 3   GLN A O   1 
ATOM   21   C CB  . GLN A 1 3   ? -67.00691 -20.67882 69.23912  1.000 106.20790 ? 3   GLN A CB  1 
ATOM   22   C CG  . GLN A 1 3   ? -68.34341 -21.28825 69.65086  1.000 111.50649 ? 3   GLN A CG  1 
ATOM   23   C CD  . GLN A 1 3   ? -68.36500 -22.79836 69.51805  1.000 110.69569 ? 3   GLN A CD  1 
ATOM   24   O OE1 . GLN A 1 3   ? -67.37863 -23.41150 69.10874  1.000 100.73495 ? 3   GLN A OE1 1 
ATOM   25   N NE2 . GLN A 1 3   ? -69.49354 -23.40698 69.86557  1.000 111.15198 ? 3   GLN A NE2 1 
ATOM   26   N N   . LEU A 1 4   ? -64.90859 -18.50510 70.88972  1.000 90.68179  ? 4   LEU A N   1 
ATOM   27   C CA  . LEU A 1 4   ? -63.49739 -18.28735 71.18217  1.000 78.31918  ? 4   LEU A CA  1 
ATOM   28   C C   . LEU A 1 4   ? -63.01094 -19.38032 72.12439  1.000 75.74572  ? 4   LEU A C   1 
ATOM   29   O O   . LEU A 1 4   ? -63.71503 -19.74399 73.07311  1.000 70.87294  ? 4   LEU A O   1 
ATOM   30   C CB  . LEU A 1 4   ? -63.26855 -16.92164 71.84059  1.000 57.51616  ? 4   LEU A CB  1 
ATOM   31   C CG  . LEU A 1 4   ? -63.78589 -15.68896 71.11030  1.000 59.40016  ? 4   LEU A CG  1 
ATOM   32   C CD1 . LEU A 1 4   ? -63.85013 -14.53666 72.08371  1.000 59.62717  ? 4   LEU A CD1 1 
ATOM   33   C CD2 . LEU A 1 4   ? -62.90823 -15.33339 69.91853  1.000 69.65650  ? 4   LEU A CD2 1 
ATOM   34   N N   . VAL A 1 5   ? -61.80665 -19.90002 71.87265  1.000 76.50565  ? 5   VAL A N   1 
ATOM   35   C CA  . VAL A 1 5   ? -61.21629 -20.94923 72.70063  1.000 78.34290  ? 5   VAL A CA  1 
ATOM   36   C C   . VAL A 1 5   ? -59.75821 -20.60252 72.99993  1.000 80.78800  ? 5   VAL A C   1 
ATOM   37   O O   . VAL A 1 5   ? -58.97845 -20.29521 72.08888  1.000 75.89395  ? 5   VAL A O   1 
ATOM   38   C CB  . VAL A 1 5   ? -61.34126 -22.34242 72.04423  1.000 78.94938  ? 5   VAL A CB  1 
ATOM   39   C CG1 . VAL A 1 5   ? -60.54137 -22.44072 70.74849  1.000 72.59379  ? 5   VAL A CG1 1 
ATOM   40   C CG2 . VAL A 1 5   ? -60.94130 -23.43298 73.02941  1.000 83.67211  ? 5   VAL A CG2 1 
ATOM   41   N N   . GLU A 1 6   ? -59.40345 -20.63579 74.28179  1.000 81.81406  ? 6   GLU A N   1 
ATOM   42   C CA  . GLU A 1 6   ? -58.06873 -20.30839 74.75519  1.000 72.54517  ? 6   GLU A CA  1 
ATOM   43   C C   . GLU A 1 6   ? -57.17957 -21.55038 74.73569  1.000 72.42182  ? 6   GLU A C   1 
ATOM   44   O O   . GLU A 1 6   ? -57.65204 -22.68452 74.64015  1.000 78.24027  ? 6   GLU A O   1 
ATOM   45   C CB  . GLU A 1 6   ? -58.14328 -19.70757 76.16160  1.000 75.89270  ? 6   GLU A CB  1 
ATOM   46   C CG  . GLU A 1 6   ? -58.87924 -18.37090 76.22191  1.000 69.43451  ? 6   GLU A CG  1 
ATOM   47   C CD  . GLU A 1 6   ? -60.38350 -18.52305 76.41425  1.000 74.70104  ? 6   GLU A CD  1 
ATOM   48   O OE1 . GLU A 1 6   ? -61.07930 -18.80647 75.41268  1.000 86.30869  ? 6   GLU A OE1 1 
ATOM   49   O OE2 . GLU A 1 6   ? -60.87598 -18.34248 77.54985  1.000 66.07551  ? 6   GLU A OE2 1 
ATOM   50   N N   . SER A 1 7   ? -55.87257 -21.32809 74.83992  1.000 69.74579  ? 7   SER A N   1 
ATOM   51   C CA  . SER A 1 7   ? -54.92498 -22.41085 74.62211  1.000 59.55949  ? 7   SER A CA  1 
ATOM   52   C C   . SER A 1 7   ? -53.57559 -22.03083 75.20938  1.000 57.67512  ? 7   SER A C   1 
ATOM   53   O O   . SER A 1 7   ? -53.21596 -20.85123 75.25935  1.000 61.48323  ? 7   SER A O   1 
ATOM   54   C CB  . SER A 1 7   ? -54.80071 -22.72425 73.12687  1.000 74.59015  ? 7   SER A CB  1 
ATOM   55   O OG  . SER A 1 7   ? -54.80799 -21.52956 72.36135  1.000 81.50690  ? 7   SER A OG  1 
ATOM   56   N N   . GLY A 1 8   ? -52.84127 -23.04650 75.65825  1.000 66.80584  ? 8   GLY A N   1 
ATOM   57   C CA  . GLY A 1 8   ? -51.54204 -22.84882 76.27321  1.000 70.18032  ? 8   GLY A CA  1 
ATOM   58   C C   . GLY A 1 8   ? -51.62904 -22.65058 77.77026  1.000 59.31983  ? 8   GLY A C   1 
ATOM   59   O O   . GLY A 1 8   ? -52.38459 -21.79741 78.23936  1.000 61.23725  ? 8   GLY A O   1 
ATOM   60   N N   . GLY A 1 9   ? -50.87945 -23.42431 78.54257  1.000 49.99995  ? 9   GLY A N   1 
ATOM   61   C CA  . GLY A 1 9   ? -50.93628 -23.21164 79.97324  1.000 63.36623  ? 9   GLY A CA  1 
ATOM   62   C C   . GLY A 1 9   ? -50.49401 -24.40095 80.78986  1.000 76.43657  ? 9   GLY A C   1 
ATOM   63   O O   . GLY A 1 9   ? -49.33334 -24.80947 80.72048  1.000 92.99234  ? 9   GLY A O   1 
ATOM   64   N N   . GLY A 1 10  ? -51.40887 -24.97252 81.56512  1.000 77.01993  ? 10  GLY A N   1 
ATOM   65   C CA  . GLY A 1 10  ? -51.01064 -26.04954 82.45017  1.000 82.29479  ? 10  GLY A CA  1 
ATOM   66   C C   . GLY A 1 10  ? -50.10591 -25.52047 83.54217  1.000 83.96054  ? 10  GLY A C   1 
ATOM   67   O O   . GLY A 1 10  ? -50.26671 -24.39659 84.02739  1.000 66.92653  ? 10  GLY A O   1 
ATOM   68   N N   . LEU A 1 11  ? -49.13267 -26.33618 83.93103  1.000 86.20409  ? 11  LEU A N   1 
ATOM   69   C CA  . LEU A 1 11  ? -48.16200 -25.98146 84.95416  1.000 63.81751  ? 11  LEU A CA  1 
ATOM   70   C C   . LEU A 1 11  ? -46.91518 -25.39885 84.29937  1.000 62.91586  ? 11  LEU A C   1 
ATOM   71   O O   . LEU A 1 11  ? -46.52764 -25.80586 83.20092  1.000 75.96007  ? 11  LEU A O   1 
ATOM   72   C CB  . LEU A 1 11  ? -47.79960 -27.21025 85.78602  1.000 56.40967  ? 11  LEU A CB  1 
ATOM   73   C CG  . LEU A 1 11  ? -46.90200 -27.02394 86.99655  1.000 60.23629  ? 11  LEU A CG  1 
ATOM   74   C CD1 . LEU A 1 11  ? -47.44705 -25.92029 87.86885  1.000 78.07883  ? 11  LEU A CD1 1 
ATOM   75   C CD2 . LEU A 1 11  ? -46.85860 -28.32382 87.75722  1.000 64.82131  ? 11  LEU A CD2 1 
ATOM   76   N N   . VAL A 1 12  ? -46.28048 -24.44036 84.97995  1.000 57.89408  ? 12  VAL A N   1 
ATOM   77   C CA  . VAL A 1 12  ? -45.16384 -23.70801 84.39227  1.000 56.90201  ? 12  VAL A CA  1 
ATOM   78   C C   . VAL A 1 12  ? -44.20086 -23.22368 85.46983  1.000 57.58869  ? 12  VAL A C   1 
ATOM   79   O O   . VAL A 1 12  ? -44.56523 -23.04152 86.63092  1.000 63.80682  ? 12  VAL A O   1 
ATOM   80   C CB  . VAL A 1 12  ? -45.65680 -22.51403 83.54219  1.000 56.66745  ? 12  VAL A CB  1 
ATOM   81   C CG1 . VAL A 1 12  ? -45.89991 -21.29246 84.42051  1.000 54.59048  ? 12  VAL A CG1 1 
ATOM   82   C CG2 . VAL A 1 12  ? -44.65805 -22.20327 82.43227  1.000 70.83012  ? 12  VAL A CG2 1 
ATOM   83   N N   . GLN A 1 13  ? -42.96694 -22.98067 85.05198  1.000 59.46713  ? 13  GLN A N   1 
ATOM   84   C CA  . GLN A 1 13  ? -41.84594 -22.60483 85.90790  1.000 59.89473  ? 13  GLN A CA  1 
ATOM   85   C C   . GLN A 1 13  ? -41.88393 -21.11261 86.23195  1.000 66.12173  ? 13  GLN A C   1 
ATOM   86   O O   . GLN A 1 13  ? -42.03209 -20.29322 85.32222  1.000 83.41290  ? 13  GLN A O   1 
ATOM   87   C CB  . GLN A 1 13  ? -40.54930 -22.97256 85.19269  1.000 60.40337  ? 13  GLN A CB  1 
ATOM   88   C CG  . GLN A 1 13  ? -39.27861 -22.36281 85.73040  1.000 71.06892  ? 13  GLN A CG  1 
ATOM   89   C CD  . GLN A 1 13  ? -38.32946 -21.99896 84.59884  1.000 82.95337  ? 13  GLN A CD  1 
ATOM   90   O OE1 . GLN A 1 13  ? -38.54588 -22.39875 83.44956  1.000 70.85277  ? 13  GLN A OE1 1 
ATOM   91   N NE2 . GLN A 1 13  ? -37.29085 -21.23068 84.90648  1.000 88.79490  ? 13  GLN A NE2 1 
ATOM   92   N N   . PRO A 1 14  ? -41.76163 -20.71739 87.51017  1.000 62.85173  ? 14  PRO A N   1 
ATOM   93   C CA  . PRO A 1 14  ? -41.58756 -19.28778 87.81149  1.000 58.01973  ? 14  PRO A CA  1 
ATOM   94   C C   . PRO A 1 14  ? -40.32276 -18.74935 87.15952  1.000 58.61452  ? 14  PRO A C   1 
ATOM   95   O O   . PRO A 1 14  ? -39.21040 -19.06166 87.59305  1.000 63.40438  ? 14  PRO A O   1 
ATOM   96   C CB  . PRO A 1 14  ? -41.51926 -19.24760 89.34468  1.000 69.49367  ? 14  PRO A CB  1 
ATOM   97   C CG  . PRO A 1 14  ? -41.18647 -20.64946 89.76888  1.000 87.63427  ? 14  PRO A CG  1 
ATOM   98   C CD  . PRO A 1 14  ? -41.78689 -21.55033 88.72552  1.000 78.69317  ? 14  PRO A CD  1 
ATOM   99   N N   . GLY A 1 15  ? -40.48594 -17.95710 86.10832  1.000 66.12158  ? 15  GLY A N   1 
ATOM   100  C CA  . GLY A 1 15  ? -39.39813 -17.54863 85.24289  1.000 73.15531  ? 15  GLY A CA  1 
ATOM   101  C C   . GLY A 1 15  ? -39.65510 -17.94739 83.80059  1.000 87.76654  ? 15  GLY A C   1 
ATOM   102  O O   . GLY A 1 15  ? -40.68463 -18.52750 83.45713  1.000 83.29456  ? 15  GLY A O   1 
ATOM   103  N N   . GLY A 1 16  ? -38.68444 -17.61670 82.94820  1.000 96.93847  ? 16  GLY A N   1 
ATOM   104  C CA  . GLY A 1 16  ? -38.84215 -17.91529 81.53151  1.000 99.28346  ? 16  GLY A CA  1 
ATOM   105  C C   . GLY A 1 16  ? -40.04511 -17.21582 80.90014  1.000 101.11143 ? 16  GLY A C   1 
ATOM   106  O O   . GLY A 1 16  ? -40.71097 -16.37062 81.49438  1.000 98.97311  ? 16  GLY A O   1 
ATOM   107  N N   . SER A 1 17  ? -40.31022 -17.60203 79.65817  1.000 103.78820 ? 17  SER A N   1 
ATOM   108  C CA  . SER A 1 17  ? -41.40734 -17.04044 78.88813  1.000 99.08367  ? 17  SER A CA  1 
ATOM   109  C C   . SER A 1 17  ? -42.54396 -18.05505 78.77274  1.000 96.22643  ? 17  SER A C   1 
ATOM   110  O O   . SER A 1 17  ? -42.43497 -19.20587 79.20692  1.000 93.61963  ? 17  SER A O   1 
ATOM   111  C CB  . SER A 1 17  ? -40.91986 -16.57759 77.51043  1.000 99.93830  ? 17  SER A CB  1 
ATOM   112  O OG  . SER A 1 17  ? -40.40672 -17.65482 76.74776  1.000 111.02646 ? 17  SER A OG  1 
ATOM   113  N N   . LEU A 1 18  ? -43.65631 -17.60109 78.19426  1.000 89.08197  ? 18  LEU A N   1 
ATOM   114  C CA  . LEU A 1 18  ? -44.83829 -18.43370 78.01549  1.000 79.68623  ? 18  LEU A CA  1 
ATOM   115  C C   . LEU A 1 18  ? -45.78984 -17.77511 77.02834  1.000 80.37156  ? 18  LEU A C   1 
ATOM   116  O O   . LEU A 1 18  ? -46.06816 -16.57602 77.13246  1.000 77.39533  ? 18  LEU A O   1 
ATOM   117  C CB  . LEU A 1 18  ? -45.54258 -18.67185 79.35065  1.000 81.30515  ? 18  LEU A CB  1 
ATOM   118  C CG  . LEU A 1 18  ? -46.55001 -19.81805 79.38410  1.000 78.74923  ? 18  LEU A CG  1 
ATOM   119  C CD1 . LEU A 1 18  ? -45.90943 -21.12743 78.93843  1.000 80.33989  ? 18  LEU A CD1 1 
ATOM   120  C CD2 . LEU A 1 18  ? -47.12952 -19.93480 80.78027  1.000 75.75622  ? 18  LEU A CD2 1 
ATOM   121  N N   . ARG A 1 19  ? -46.29342 -18.54958 76.07217  1.000 85.90978  ? 19  ARG A N   1 
ATOM   122  C CA  . ARG A 1 19  ? -47.16633 -18.04954 75.01814  1.000 86.29652  ? 19  ARG A CA  1 
ATOM   123  C C   . ARG A 1 19  ? -48.59540 -18.54250 75.22577  1.000 77.81669  ? 19  ARG A C   1 
ATOM   124  O O   . ARG A 1 19  ? -48.81925 -19.72299 75.51645  1.000 76.00218  ? 19  ARG A O   1 
ATOM   125  C CB  . ARG A 1 19  ? -46.66814 -18.49362 73.63457  1.000 96.36291  ? 19  ARG A CB  1 
ATOM   126  C CG  . ARG A 1 19  ? -45.62212 -17.58649 72.96436  1.000 98.77656  ? 19  ARG A CG  1 
ATOM   127  C CD  . ARG A 1 19  ? -44.24164 -17.67997 73.59983  1.000 105.01091 ? 19  ARG A CD  1 
ATOM   128  N NE  . ARG A 1 19  ? -43.80950 -19.05573 73.79838  1.000 112.36285 ? 19  ARG A NE  1 
ATOM   129  C CZ  . ARG A 1 19  ? -42.64333 -19.40452 74.32428  1.000 108.80157 ? 19  ARG A CZ  1 
ATOM   130  N NH1 . ARG A 1 19  ? -41.74557 -18.49880 74.67904  1.000 103.37540 ? 19  ARG A NH1 1 
ATOM   131  N NH2 . ARG A 1 19  ? -42.37146 -20.69469 74.50076  1.000 102.04496 ? 19  ARG A NH2 1 
ATOM   132  N N   . LEU A 1 20  ? -49.56206 -17.63157 75.06988  1.000 73.41276  ? 20  LEU A N   1 
ATOM   133  C CA  . LEU A 1 20  ? -50.98256 -17.96559 75.07530  1.000 73.46432  ? 20  LEU A CA  1 
ATOM   134  C C   . LEU A 1 20  ? -51.64202 -17.40654 73.82378  1.000 69.29437  ? 20  LEU A C   1 
ATOM   135  O O   . LEU A 1 20  ? -51.29149 -16.31518 73.36403  1.000 66.76739  ? 20  LEU A O   1 
ATOM   136  C CB  . LEU A 1 20  ? -51.71326 -17.41764 76.31171  1.000 58.75499  ? 20  LEU A CB  1 
ATOM   137  C CG  . LEU A 1 20  ? -51.10744 -17.61461 77.69955  1.000 55.75552  ? 20  LEU A CG  1 
ATOM   138  C CD1 . LEU A 1 20  ? -52.05165 -17.05266 78.75547  1.000 42.10317  ? 20  LEU A CD1 1 
ATOM   139  C CD2 . LEU A 1 20  ? -50.78518 -19.07900 77.96591  1.000 59.67787  ? 20  LEU A CD2 1 
ATOM   140  N N   . SER A 1 21  ? -52.61080 -18.14828 73.28323  1.000 67.97111  ? 21  SER A N   1 
ATOM   141  C CA  . SER A 1 21  ? -53.27395 -17.74272 72.05354  1.000 65.15815  ? 21  SER A CA  1 
ATOM   142  C C   . SER A 1 21  ? -54.77084 -18.01896 72.14117  1.000 66.15233  ? 21  SER A C   1 
ATOM   143  O O   . SER A 1 21  ? -55.28550 -18.51901 73.14665  1.000 65.58991  ? 21  SER A O   1 
ATOM   144  C CB  . SER A 1 21  ? -52.66689 -18.43753 70.82633  1.000 63.80953  ? 21  SER A CB  1 
ATOM   145  O OG  . SER A 1 21  ? -52.81164 -19.84469 70.88892  1.000 75.01304  ? 21  SER A OG  1 
ATOM   146  N N   . CYS A 1 22  ? -55.46356 -17.68787 71.05334  1.000 66.55502  ? 22  CYS A N   1 
ATOM   147  C CA  . CYS A 1 22  ? -56.91246 -17.75661 70.95927  1.000 67.46257  ? 22  CYS A CA  1 
ATOM   148  C C   . CYS A 1 22  ? -57.27250 -18.24034 69.56204  1.000 68.78560  ? 22  CYS A C   1 
ATOM   149  O O   . CYS A 1 22  ? -56.42153 -18.31904 68.67142  1.000 76.02643  ? 22  CYS A O   1 
ATOM   150  C CB  . CYS A 1 22  ? -57.54493 -16.38668 71.25179  1.000 68.46221  ? 22  CYS A CB  1 
ATOM   151  S SG  . CYS A 1 22  ? -59.26027 -16.37191 71.84280  1.000 85.65035  ? 22  CYS A SG  1 
ATOM   152  N N   . ALA A 1 23  ? -58.54989 -18.56152 69.37044  1.000 66.92805  ? 23  ALA A N   1 
ATOM   153  C CA  . ALA A 1 23  ? -59.04155 -19.02294 68.08033  1.000 72.31774  ? 23  ALA A CA  1 
ATOM   154  C C   . ALA A 1 23  ? -60.42609 -18.45211 67.81754  1.000 75.46530  ? 23  ALA A C   1 
ATOM   155  O O   . ALA A 1 23  ? -61.27466 -18.41398 68.71481  1.000 72.96434  ? 23  ALA A O   1 
ATOM   156  C CB  . ALA A 1 23  ? -59.08903 -20.55143 68.00518  1.000 89.53432  ? 23  ALA A CB  1 
ATOM   157  N N   . ALA A 1 24  ? -60.64964 -18.04022 66.57053  1.000 76.88433  ? 24  ALA A N   1 
ATOM   158  C CA  . ALA A 1 24  ? -61.86596 -17.35774 66.15036  1.000 79.02701  ? 24  ALA A CA  1 
ATOM   159  C C   . ALA A 1 24  ? -62.66044 -18.22483 65.18609  1.000 92.78815  ? 24  ALA A C   1 
ATOM   160  O O   . ALA A 1 24  ? -62.12181 -18.70141 64.18136  1.000 100.18911 ? 24  ALA A O   1 
ATOM   161  C CB  . ALA A 1 24  ? -61.53435 -16.02505 65.48081  1.000 80.72482  ? 24  ALA A CB  1 
ATOM   162  N N   . SER A 1 25  ? -63.94688 -18.39358 65.47844  1.000 94.03365  ? 25  SER A N   1 
ATOM   163  C CA  . SER A 1 25  ? -64.84450 -19.14970 64.61726  1.000 94.61803  ? 25  SER A CA  1 
ATOM   164  C C   . SER A 1 25  ? -66.26865 -18.68547 64.88179  1.000 99.43178  ? 25  SER A C   1 
ATOM   165  O O   . SER A 1 25  ? -66.67554 -18.54695 66.04033  1.000 104.73682 ? 25  SER A O   1 
ATOM   166  C CB  . SER A 1 25  ? -64.70032 -20.65294 64.86411  1.000 96.38321  ? 25  SER A CB  1 
ATOM   167  O OG  . SER A 1 25  ? -64.75598 -20.94201 66.25141  1.000 107.00450 ? 25  SER A OG  1 
ATOM   168  N N   . GLY A 1 26  ? -67.01474 -18.43965 63.80914  1.000 96.23077  ? 26  GLY A N   1 
ATOM   169  C CA  . GLY A 1 26  ? -68.37795 -17.97094 63.90673  1.000 100.06771 ? 26  GLY A CA  1 
ATOM   170  C C   . GLY A 1 26  ? -68.55612 -16.49438 63.65634  1.000 99.11900  ? 26  GLY A C   1 
ATOM   171  O O   . GLY A 1 26  ? -69.69466 -16.01092 63.68781  1.000 104.01434 ? 26  GLY A O   1 
ATOM   172  N N   . PHE A 1 27  ? -67.47238 -15.76523 63.41007  1.000 95.60135  ? 27  PHE A N   1 
ATOM   173  C CA  . PHE A 1 27  ? -67.54854 -14.33834 63.15144  1.000 94.76801  ? 27  PHE A CA  1 
ATOM   174  C C   . PHE A 1 27  ? -66.39073 -13.94540 62.24657  1.000 92.61104  ? 27  PHE A C   1 
ATOM   175  O O   . PHE A 1 27  ? -65.46578 -14.72559 62.00552  1.000 93.31171  ? 27  PHE A O   1 
ATOM   176  C CB  . PHE A 1 27  ? -67.52863 -13.53372 64.45318  1.000 98.06224  ? 27  PHE A CB  1 
ATOM   177  C CG  . PHE A 1 27  ? -66.18599 -13.49580 65.12372  1.000 101.58049 ? 27  PHE A CG  1 
ATOM   178  C CD1 . PHE A 1 27  ? -65.77501 -14.52870 65.95155  1.000 103.32448 ? 27  PHE A CD1 1 
ATOM   179  C CD2 . PHE A 1 27  ? -65.32993 -12.42645 64.91743  1.000 100.32402 ? 27  PHE A CD2 1 
ATOM   180  C CE1 . PHE A 1 27  ? -64.53721 -14.48981 66.56853  1.000 101.97478 ? 27  PHE A CE1 1 
ATOM   181  C CE2 . PHE A 1 27  ? -64.09221 -12.38149 65.52429  1.000 96.96354  ? 27  PHE A CE2 1 
ATOM   182  C CZ  . PHE A 1 27  ? -63.69380 -13.41246 66.35251  1.000 100.99028 ? 27  PHE A CZ  1 
ATOM   183  N N   . THR A 1 28  ? -66.45450 -12.71667 61.74601  1.000 86.50712  ? 28  THR A N   1 
ATOM   184  C CA  . THR A 1 28  ? -65.41592 -12.17264 60.88246  1.000 87.61816  ? 28  THR A CA  1 
ATOM   185  C C   . THR A 1 28  ? -64.37517 -11.46316 61.74050  1.000 88.49067  ? 28  THR A C   1 
ATOM   186  O O   . THR A 1 28  ? -64.70556 -10.52392 62.47149  1.000 92.73786  ? 28  THR A O   1 
ATOM   187  C CB  . THR A 1 28  ? -66.02281 -11.21540 59.86078  1.000 87.61634  ? 28  THR A CB  1 
ATOM   188  O OG1 . THR A 1 28  ? -66.29969 -9.96428  60.49455  1.000 81.38115  ? 28  THR A OG1 1 
ATOM   189  C CG2 . THR A 1 28  ? -67.31313 -11.78100 59.31515  1.000 94.52855  ? 28  THR A CG2 1 
ATOM   190  N N   . PHE A 1 29  ? -63.11986 -11.90890 61.64308  1.000 87.53737  ? 29  PHE A N   1 
ATOM   191  C CA  . PHE A 1 29  ? -62.07658 -11.40497 62.53322  1.000 82.54109  ? 29  PHE A CA  1 
ATOM   192  C C   . PHE A 1 29  ? -61.79210 -9.92773  62.29183  1.000 81.54629  ? 29  PHE A C   1 
ATOM   193  O O   . PHE A 1 29  ? -61.72688 -9.13402  63.23689  1.000 84.09009  ? 29  PHE A O   1 
ATOM   194  C CB  . PHE A 1 29  ? -60.79908 -12.22794 62.36726  1.000 86.66517  ? 29  PHE A CB  1 
ATOM   195  C CG  . PHE A 1 29  ? -59.99802 -12.36898 63.63353  1.000 71.27409  ? 29  PHE A CG  1 
ATOM   196  C CD1 . PHE A 1 29  ? -59.76804 -11.27301 64.44576  1.000 63.85784  ? 29  PHE A CD1 1 
ATOM   197  C CD2 . PHE A 1 29  ? -59.45742 -13.58998 63.99969  1.000 70.56382  ? 29  PHE A CD2 1 
ATOM   198  C CE1 . PHE A 1 29  ? -59.03103 -11.38785 65.60398  1.000 63.38261  ? 29  PHE A CE1 1 
ATOM   199  C CE2 . PHE A 1 29  ? -58.71608 -13.71009 65.16049  1.000 65.49442  ? 29  PHE A CE2 1 
ATOM   200  C CZ  . PHE A 1 29  ? -58.50347 -12.60774 65.96103  1.000 66.70887  ? 29  PHE A CZ  1 
ATOM   201  N N   . THR A 1 30  ? -61.61512 -9.53614  61.03169  1.000 75.12833  ? 30  THR A N   1 
ATOM   202  C CA  . THR A 1 30  ? -61.14293 -8.18793  60.73324  1.000 76.21506  ? 30  THR A CA  1 
ATOM   203  C C   . THR A 1 30  ? -62.08056 -7.09358  61.23679  1.000 74.65423  ? 30  THR A C   1 
ATOM   204  O O   . THR A 1 30  ? -61.74206 -5.91006  61.12130  1.000 83.85785  ? 30  THR A O   1 
ATOM   205  C CB  . THR A 1 30  ? -60.92792 -8.04269  59.22341  1.000 97.28996  ? 30  THR A CB  1 
ATOM   206  O OG1 . THR A 1 30  ? -60.41376 -6.73572  58.93066  1.000 114.53650 ? 30  THR A OG1 1 
ATOM   207  C CG2 . THR A 1 30  ? -62.23236 -8.24578  58.47964  1.000 100.73362 ? 30  THR A CG2 1 
ATOM   208  N N   . THR A 1 31  ? -63.23533 -7.44689  61.79838  1.000 65.73148  ? 31  THR A N   1 
ATOM   209  C CA  . THR A 1 31  ? -64.15091 -6.45291  62.33850  1.000 72.56434  ? 31  THR A CA  1 
ATOM   210  C C   . THR A 1 31  ? -64.16111 -6.40341  63.85862  1.000 81.73856  ? 31  THR A C   1 
ATOM   211  O O   . THR A 1 31  ? -64.77148 -5.49042  64.42454  1.000 90.88696  ? 31  THR A O   1 
ATOM   212  C CB  . THR A 1 31  ? -65.58252 -6.70577  61.84782  1.000 82.09145  ? 31  THR A CB  1 
ATOM   213  O OG1 . THR A 1 31  ? -66.35150 -5.50647  61.99263  1.000 95.69740  ? 31  THR A OG1 1 
ATOM   214  C CG2 . THR A 1 31  ? -66.24174 -7.79847  62.66058  1.000 74.11254  ? 31  THR A CG2 1 
ATOM   215  N N   . TYR A 1 32  ? -63.51657 -7.35127  64.53037  1.000 85.88453  ? 32  TYR A N   1 
ATOM   216  C CA  . TYR A 1 32  ? -63.57812 -7.46432  65.97912  1.000 84.22794  ? 32  TYR A CA  1 
ATOM   217  C C   . TYR A 1 32  ? -62.24498 -7.07054  66.60053  1.000 76.33961  ? 32  TYR A C   1 
ATOM   218  O O   . TYR A 1 32  ? -61.17787 -7.34048  66.03902  1.000 76.50624  ? 32  TYR A O   1 
ATOM   219  C CB  . TYR A 1 32  ? -63.94941 -8.89189  66.39653  1.000 82.83038  ? 32  TYR A CB  1 
ATOM   220  C CG  . TYR A 1 32  ? -65.41393 -9.08773  66.73015  1.000 86.34460  ? 32  TYR A CG  1 
ATOM   221  C CD1 . TYR A 1 32  ? -66.35173 -9.31808  65.73264  1.000 89.13113  ? 32  TYR A CD1 1 
ATOM   222  C CD2 . TYR A 1 32  ? -65.85254 -9.07109  68.04808  1.000 94.29947  ? 32  TYR A CD2 1 
ATOM   223  C CE1 . TYR A 1 32  ? -67.68851 -9.50358  66.03620  1.000 96.97508  ? 32  TYR A CE1 1 
ATOM   224  C CE2 . TYR A 1 32  ? -67.18628 -9.25621  68.36499  1.000 97.12009  ? 32  TYR A CE2 1 
ATOM   225  C CZ  . TYR A 1 32  ? -68.10073 -9.47114  67.35723  1.000 96.61916  ? 32  TYR A CZ  1 
ATOM   226  O OH  . TYR A 1 32  ? -69.42896 -9.65673  67.67315  1.000 99.16067  ? 32  TYR A OH  1 
ATOM   227  N N   . ALA A 1 33  ? -62.31294 -6.42340  67.75469  1.000 69.79621  ? 33  ALA A N   1 
ATOM   228  C CA  . ALA A 1 33  ? -61.13443 -6.11277  68.54592  1.000 72.04679  ? 33  ALA A CA  1 
ATOM   229  C C   . ALA A 1 33  ? -61.06582 -7.06839  69.73439  1.000 75.20323  ? 33  ALA A C   1 
ATOM   230  O O   . ALA A 1 33  ? -62.08813 -7.58949  70.18656  1.000 78.00799  ? 33  ALA A O   1 
ATOM   231  C CB  . ALA A 1 33  ? -61.16687 -4.65634  69.01183  1.000 70.45371  ? 33  ALA A CB  1 
ATOM   232  N N   . MET A 1 34  ? -59.85336 -7.31061  70.23202  1.000 66.95085  ? 34  MET A N   1 
ATOM   233  C CA  . MET A 1 34  ? -59.61664 -8.39539  71.17494  1.000 55.88534  ? 34  MET A CA  1 
ATOM   234  C C   . MET A 1 34  ? -59.16774 -7.86275  72.53084  1.000 59.85920  ? 34  MET A C   1 
ATOM   235  O O   . MET A 1 34  ? -58.66027 -6.74375  72.64599  1.000 61.76403  ? 34  MET A O   1 
ATOM   236  C CB  . MET A 1 34  ? -58.57043 -9.37448  70.63039  1.000 53.80432  ? 34  MET A CB  1 
ATOM   237  C CG  . MET A 1 34  ? -58.97534 -10.04224 69.32292  1.000 63.19652  ? 34  MET A CG  1 
ATOM   238  S SD  . MET A 1 34  ? -60.53996 -10.93452 69.43663  1.000 51.98133  ? 34  MET A SD  1 
ATOM   239  C CE  . MET A 1 34  ? -60.10577 -12.23310 70.58605  1.000 63.43103  ? 34  MET A CE  1 
ATOM   240  N N   . HIS A 1 35  ? -59.38541 -8.68314  73.56545  1.000 64.42116  ? 35  HIS A N   1 
ATOM   241  C CA  . HIS A 1 35  ? -59.00737 -8.36618  74.93843  1.000 55.53865  ? 35  HIS A CA  1 
ATOM   242  C C   . HIS A 1 35  ? -58.41239 -9.60182  75.60147  1.000 48.46633  ? 35  HIS A C   1 
ATOM   243  O O   . HIS A 1 35  ? -58.79316 -10.73651 75.29950  1.000 50.03230  ? 35  HIS A O   1 
ATOM   244  C CB  . HIS A 1 35  ? -60.19857 -7.89927  75.79965  1.000 52.17759  ? 35  HIS A CB  1 
ATOM   245  C CG  . HIS A 1 35  ? -60.88954 -6.67405  75.28948  1.000 55.53435  ? 35  HIS A CG  1 
ATOM   246  N ND1 . HIS A 1 35  ? -61.16987 -5.59023  76.09405  1.000 66.86796  ? 35  HIS A ND1 1 
ATOM   247  C CD2 . HIS A 1 35  ? -61.39464 -6.37709  74.06906  1.000 56.74628  ? 35  HIS A CD2 1 
ATOM   248  C CE1 . HIS A 1 35  ? -61.79510 -4.66824  75.38424  1.000 69.26653  ? 35  HIS A CE1 1 
ATOM   249  N NE2 . HIS A 1 35  ? -61.94310 -5.12072  74.15194  1.000 63.35644  ? 35  HIS A NE2 1 
ATOM   250  N N   . TRP A 1 36  ? -57.47468 -9.37154  76.51213  1.000 41.76577  ? 36  TRP A N   1 
ATOM   251  C CA  . TRP A 1 36  ? -56.97412 -10.40619 77.40695  1.000 49.15798  ? 36  TRP A CA  1 
ATOM   252  C C   . TRP A 1 36  ? -57.31932 -9.99154  78.82915  1.000 52.92955  ? 36  TRP A C   1 
ATOM   253  O O   . TRP A 1 36  ? -57.00253 -8.87384  79.24774  1.000 54.48783  ? 36  TRP A O   1 
ATOM   254  C CB  . TRP A 1 36  ? -55.46550 -10.61295 77.25357  1.000 49.18106  ? 36  TRP A CB  1 
ATOM   255  C CG  . TRP A 1 36  ? -55.03115 -11.51617 76.11511  1.000 49.35007  ? 36  TRP A CG  1 
ATOM   256  C CD1 . TRP A 1 36  ? -54.31040 -11.15930 75.00906  1.000 54.19763  ? 36  TRP A CD1 1 
ATOM   257  C CD2 . TRP A 1 36  ? -55.27109 -12.92352 75.99486  1.000 51.75322  ? 36  TRP A CD2 1 
ATOM   258  N NE1 . TRP A 1 36  ? -54.09805 -12.25499 74.20586  1.000 54.33226  ? 36  TRP A NE1 1 
ATOM   259  C CE2 . TRP A 1 36  ? -54.67581 -13.35032 74.79067  1.000 55.73489  ? 36  TRP A CE2 1 
ATOM   260  C CE3 . TRP A 1 36  ? -55.93588 -13.86324 76.78599  1.000 53.70423  ? 36  TRP A CE3 1 
ATOM   261  C CZ2 . TRP A 1 36  ? -54.72683 -14.67501 74.36185  1.000 60.88578  ? 36  TRP A CZ2 1 
ATOM   262  C CZ3 . TRP A 1 36  ? -55.98824 -15.17734 76.35803  1.000 56.25672  ? 36  TRP A CZ3 1 
ATOM   263  C CH2 . TRP A 1 36  ? -55.38633 -15.57184 75.15865  1.000 57.43328  ? 36  TRP A CH2 1 
ATOM   264  N N   . VAL A 1 37  ? -57.99740 -10.87005 79.55385  1.000 51.37136  ? 37  VAL A N   1 
ATOM   265  C CA  . VAL A 1 37  ? -58.42051 -10.59498 80.91971  1.000 48.91314  ? 37  VAL A CA  1 
ATOM   266  C C   . VAL A 1 37  ? -58.17359 -11.84307 81.75113  1.000 53.54015  ? 37  VAL A C   1 
ATOM   267  O O   . VAL A 1 37  ? -58.44126 -12.96103 81.29932  1.000 64.71989  ? 37  VAL A O   1 
ATOM   268  C CB  . VAL A 1 37  ? -59.90560 -10.17254 80.98613  1.000 53.28858  ? 37  VAL A CB  1 
ATOM   269  C CG1 . VAL A 1 37  ? -60.38255 -10.15069 82.41571  1.000 68.69687  ? 37  VAL A CG1 1 
ATOM   270  C CG2 . VAL A 1 37  ? -60.11024 -8.80402  80.34719  1.000 52.59879  ? 37  VAL A CG2 1 
ATOM   271  N N   . ARG A 1 38  ? -57.66123 -11.65468 82.96050  1.000 46.85504  ? 38  ARG A N   1 
ATOM   272  C CA  . ARG A 1 38  ? -57.28566 -12.75473 83.83051  1.000 46.55068  ? 38  ARG A CA  1 
ATOM   273  C C   . ARG A 1 38  ? -58.05048 -12.67020 85.14714  1.000 56.30381  ? 38  ARG A C   1 
ATOM   274  O O   . ARG A 1 38  ? -58.73978 -11.68957 85.43497  1.000 59.37684  ? 38  ARG A O   1 
ATOM   275  C CB  . ARG A 1 38  ? -55.76833 -12.75442 84.06293  1.000 49.69468  ? 38  ARG A CB  1 
ATOM   276  C CG  . ARG A 1 38  ? -55.26768 -11.55223 84.86088  1.000 59.81745  ? 38  ARG A CG  1 
ATOM   277  C CD  . ARG A 1 38  ? -53.83182 -11.73909 85.34333  1.000 54.87872  ? 38  ARG A CD  1 
ATOM   278  N NE  . ARG A 1 38  ? -53.31541 -10.56134 86.03309  1.000 52.60762  ? 38  ARG A NE  1 
ATOM   279  C CZ  . ARG A 1 38  ? -52.15461 -10.51822 86.67376  1.000 60.63314  ? 38  ARG A CZ  1 
ATOM   280  N NH1 . ARG A 1 38  ? -51.36047 -11.57450 86.73670  1.000 62.46636  ? 38  ARG A NH1 1 
ATOM   281  N NH2 . ARG A 1 38  ? -51.78114 -9.38716  87.26672  1.000 70.90277  ? 38  ARG A NH2 1 
ATOM   282  N N   . GLN A 1 39  ? -57.91997 -13.72627 85.95274  1.000 61.62322  ? 39  GLN A N   1 
ATOM   283  C CA  . GLN A 1 39  ? -58.65029 -13.83340 87.21759  1.000 64.35459  ? 39  GLN A CA  1 
ATOM   284  C C   . GLN A 1 39  ? -57.95846 -14.85397 88.11430  1.000 63.39025  ? 39  GLN A C   1 
ATOM   285  O O   . GLN A 1 39  ? -57.93630 -16.04438 87.79151  1.000 66.89101  ? 39  GLN A O   1 
ATOM   286  C CB  . GLN A 1 39  ? -60.09851 -14.22505 86.96838  1.000 61.11785  ? 39  GLN A CB  1 
ATOM   287  C CG  . GLN A 1 39  ? -60.97738 -14.12476 88.19978  1.000 64.74546  ? 39  GLN A CG  1 
ATOM   288  C CD  . GLN A 1 39  ? -62.43344 -14.42500 87.90301  1.000 71.52007  ? 39  GLN A CD  1 
ATOM   289  O OE1 . GLN A 1 39  ? -62.78359 -14.82050 86.78994  1.000 67.28080  ? 39  GLN A OE1 1 
ATOM   290  N NE2 . GLN A 1 39  ? -63.29089 -14.24502 88.90236  1.000 74.71488  ? 39  GLN A NE2 1 
ATOM   291  N N   . SER A 1 40  ? -57.41798 -14.39459 89.24082  1.000 62.78932  ? 40  SER A N   1 
ATOM   292  C CA  . SER A 1 40  ? -56.88332 -15.30907 90.23464  1.000 69.07464  ? 40  SER A CA  1 
ATOM   293  C C   . SER A 1 40  ? -58.01048 -16.13582 90.85427  1.000 71.11949  ? 40  SER A C   1 
ATOM   294  O O   . SER A 1 40  ? -59.17968 -15.74603 90.80325  1.000 78.77686  ? 40  SER A O   1 
ATOM   295  C CB  . SER A 1 40  ? -56.13206 -14.53783 91.31994  1.000 75.02656  ? 40  SER A CB  1 
ATOM   296  O OG  . SER A 1 40  ? -55.00488 -13.87020 90.78164  1.000 81.19781  ? 40  SER A OG  1 
ATOM   297  N N   . PRO A 1 41  ? -57.68760 -17.29740 91.42446  1.000 63.78785  ? 41  PRO A N   1 
ATOM   298  C CA  . PRO A 1 41  ? -58.72747 -18.10439 92.07227  1.000 66.22471  ? 41  PRO A CA  1 
ATOM   299  C C   . PRO A 1 41  ? -59.38831 -17.34821 93.21479  1.000 72.18055  ? 41  PRO A C   1 
ATOM   300  O O   . PRO A 1 41  ? -58.72401 -16.68463 94.01594  1.000 75.92849  ? 41  PRO A O   1 
ATOM   301  C CB  . PRO A 1 41  ? -57.95968 -19.32850 92.57877  1.000 76.77854  ? 41  PRO A CB  1 
ATOM   302  C CG  . PRO A 1 41  ? -56.81546 -19.44471 91.64259  1.000 78.42757  ? 41  PRO A CG  1 
ATOM   303  C CD  . PRO A 1 41  ? -56.41204 -18.02685 91.33876  1.000 67.89126  ? 41  PRO A CD  1 
ATOM   304  N N   . GLY A 1 42  ? -60.71659 -17.44161 93.26330  1.000 78.10558  ? 42  GLY A N   1 
ATOM   305  C CA  . GLY A 1 42  ? -61.51338 -16.85128 94.32258  1.000 81.20085  ? 42  GLY A CA  1 
ATOM   306  C C   . GLY A 1 42  ? -61.28599 -15.36668 94.50253  1.000 70.02460  ? 42  GLY A C   1 
ATOM   307  O O   . GLY A 1 42  ? -61.40528 -14.83915 95.61366  1.000 81.30207  ? 42  GLY A O   1 
ATOM   308  N N   . LYS A 1 43  ? -60.95018 -14.67853 93.41277  1.000 55.57376  ? 43  LYS A N   1 
ATOM   309  C CA  . LYS A 1 43  ? -60.63829 -13.25756 93.45497  1.000 60.91861  ? 43  LYS A CA  1 
ATOM   310  C C   . LYS A 1 43  ? -61.31009 -12.58226 92.26720  1.000 61.76021  ? 43  LYS A C   1 
ATOM   311  O O   . LYS A 1 43  ? -61.97512 -13.23027 91.45394  1.000 62.20637  ? 43  LYS A O   1 
ATOM   312  C CB  . LYS A 1 43  ? -59.12164 -13.03178 93.47500  1.000 64.30441  ? 43  LYS A CB  1 
ATOM   313  C CG  . LYS A 1 43  ? -58.53734 -13.08736 94.87647  1.000 79.93444  ? 43  LYS A CG  1 
ATOM   314  C CD  . LYS A 1 43  ? -57.04121 -12.82643 94.88186  1.000 95.34115  ? 43  LYS A CD  1 
ATOM   315  C CE  . LYS A 1 43  ? -56.47552 -12.87211 96.30193  1.000 105.79494 ? 43  LYS A CE  1 
ATOM   316  N NZ  . LYS A 1 43  ? -56.73561 -14.17616 96.98472  1.000 88.50771  ? 43  LYS A NZ  1 
ATOM   317  N N   . GLY A 1 44  ? -61.14194 -11.26340 92.17590  1.000 61.67381  ? 44  GLY A N   1 
ATOM   318  C CA  . GLY A 1 44  ? -61.80054 -10.47905 91.15249  1.000 65.31265  ? 44  GLY A CA  1 
ATOM   319  C C   . GLY A 1 44  ? -61.13013 -10.56500 89.78991  1.000 67.71657  ? 44  GLY A C   1 
ATOM   320  O O   . GLY A 1 44  ? -60.12858 -11.25252 89.58604  1.000 68.11132  ? 44  GLY A O   1 
ATOM   321  N N   . LEU A 1 45  ? -61.71655 -9.84114  88.83669  1.000 62.12352  ? 45  LEU A N   1 
ATOM   322  C CA  . LEU A 1 45  ? -61.19134 -9.74571  87.48192  1.000 54.64178  ? 45  LEU A CA  1 
ATOM   323  C C   . LEU A 1 45  ? -60.17445 -8.61657  87.37670  1.000 56.97538  ? 45  LEU A C   1 
ATOM   324  O O   . LEU A 1 45  ? -60.24524 -7.61851  88.10016  1.000 65.41132  ? 45  LEU A O   1 
ATOM   325  C CB  . LEU A 1 45  ? -62.31338 -9.50494  86.47259  1.000 50.69543  ? 45  LEU A CB  1 
ATOM   326  C CG  . LEU A 1 45  ? -63.20317 -10.70455 86.15244  1.000 62.00755  ? 45  LEU A CG  1 
ATOM   327  C CD1 . LEU A 1 45  ? -64.49610 -10.25217 85.49038  1.000 55.44746  ? 45  LEU A CD1 1 
ATOM   328  C CD2 . LEU A 1 45  ? -62.46267 -11.70851 85.28420  1.000 64.75172  ? 45  LEU A CD2 1 
ATOM   329  N N   . GLU A 1 46  ? -59.22835 -8.77681  86.45405  1.000 48.97796  ? 46  GLU A N   1 
ATOM   330  C CA  . GLU A 1 46  ? -58.20777 -7.76466  86.21423  1.000 52.08314  ? 46  GLU A CA  1 
ATOM   331  C C   . GLU A 1 46  ? -57.97434 -7.63964  84.72164  1.000 51.61086  ? 46  GLU A C   1 
ATOM   332  O O   . GLU A 1 46  ? -57.73818 -8.64330  84.04489  1.000 58.37182  ? 46  GLU A O   1 
ATOM   333  C CB  . GLU A 1 46  ? -56.88880 -8.10932  86.92270  1.000 59.05084  ? 46  GLU A CB  1 
ATOM   334  C CG  . GLU A 1 46  ? -55.80072 -7.04952  86.74974  1.000 64.09038  ? 46  GLU A CG  1 
ATOM   335  C CD  . GLU A 1 46  ? -54.54186 -7.35607  87.54443  1.000 72.34666  ? 46  GLU A CD  1 
ATOM   336  O OE1 . GLU A 1 46  ? -54.45940 -8.45586  88.13387  1.000 74.26396  ? 46  GLU A OE1 1 
ATOM   337  O OE2 . GLU A 1 46  ? -53.63446 -6.49688  87.57690  1.000 75.12927  ? 46  GLU A OE2 1 
ATOM   338  N N   . TRP A 1 47  ? -58.03975 -6.41541  84.21383  1.000 49.57716  ? 47  TRP A N   1 
ATOM   339  C CA  . TRP A 1 47  ? -57.80719 -6.20101  82.79614  1.000 53.06010  ? 47  TRP A CA  1 
ATOM   340  C C   . TRP A 1 47  ? -56.32799 -6.32975  82.46174  1.000 55.65964  ? 47  TRP A C   1 
ATOM   341  O O   . TRP A 1 47  ? -55.45307 -6.14644  83.31213  1.000 70.19928  ? 47  TRP A O   1 
ATOM   342  C CB  . TRP A 1 47  ? -58.29075 -4.82014  82.37554  1.000 59.90282  ? 47  TRP A CB  1 
ATOM   343  C CG  . TRP A 1 47  ? -58.14802 -4.57620  80.91814  1.000 55.01134  ? 47  TRP A CG  1 
ATOM   344  C CD1 . TRP A 1 47  ? -58.73115 -5.27923  79.90832  1.000 55.62907  ? 47  TRP A CD1 1 
ATOM   345  C CD2 . TRP A 1 47  ? -57.34426 -3.57049  80.29622  1.000 51.09488  ? 47  TRP A CD2 1 
ATOM   346  N NE1 . TRP A 1 47  ? -58.35296 -4.76361  78.69474  1.000 56.16359  ? 47  TRP A NE1 1 
ATOM   347  C CE2 . TRP A 1 47  ? -57.50244 -3.71189  78.90723  1.000 48.99253  ? 47  TRP A CE2 1 
ATOM   348  C CE3 . TRP A 1 47  ? -56.51694 -2.55495  80.78024  1.000 56.72520  ? 47  TRP A CE3 1 
ATOM   349  C CZ2 . TRP A 1 47  ? -56.86276 -2.88222  77.99864  1.000 53.69251  ? 47  TRP A CZ2 1 
ATOM   350  C CZ3 . TRP A 1 47  ? -55.88226 -1.73311  79.87583  1.000 56.36999  ? 47  TRP A CZ3 1 
ATOM   351  C CH2 . TRP A 1 47  ? -56.05824 -1.90007  78.50140  1.000 58.25594  ? 47  TRP A CH2 1 
ATOM   352  N N   . LEU A 1 48  ? -56.05060 -6.62072  81.19186  1.000 46.57518  ? 48  LEU A N   1 
ATOM   353  C CA  . LEU A 1 48  ? -54.66754 -6.66911  80.74244  1.000 51.80344  ? 48  LEU A CA  1 
ATOM   354  C C   . LEU A 1 48  ? -54.41259 -5.82490  79.49907  1.000 59.83453  ? 48  LEU A C   1 
ATOM   355  O O   . LEU A 1 48  ? -53.78621 -4.76095  79.58597  1.000 63.08185  ? 48  LEU A O   1 
ATOM   356  C CB  . LEU A 1 48  ? -54.24197 -8.11559  80.49133  1.000 48.13496  ? 48  LEU A CB  1 
ATOM   357  C CG  . LEU A 1 48  ? -54.17945 -9.00011  81.73486  1.000 44.47559  ? 48  LEU A CG  1 
ATOM   358  C CD1 . LEU A 1 48  ? -54.50700 -10.43861 81.37450  1.000 50.44597  ? 48  LEU A CD1 1 
ATOM   359  C CD2 . LEU A 1 48  ? -52.80188 -8.91762  82.36189  1.000 43.10126  ? 48  LEU A CD2 1 
ATOM   360  N N   . ALA A 1 49  ? -54.89203 -6.26776  78.33794  1.000 58.55378  ? 49  ALA A N   1 
ATOM   361  C CA  . ALA A 1 49  ? -54.50752 -5.61283  77.09308  1.000 54.82365  ? 49  ALA A CA  1 
ATOM   362  C C   . ALA A 1 49  ? -55.66937 -5.60159  76.10492  1.000 51.91602  ? 49  ALA A C   1 
ATOM   363  O O   . ALA A 1 49  ? -56.70607 -6.23485  76.31900  1.000 48.33527  ? 49  ALA A O   1 
ATOM   364  C CB  . ALA A 1 49  ? -53.28213 -6.28995  76.46562  1.000 53.64199  ? 49  ALA A CB  1 
ATOM   365  N N   . SER A 1 50  ? -55.46643 -4.87179  75.00211  1.000 51.41254  ? 50  SER A N   1 
ATOM   366  C CA  . SER A 1 50  ? -56.42204 -4.75907  73.90485  1.000 52.57481  ? 50  SER A CA  1 
ATOM   367  C C   . SER A 1 50  ? -55.69047 -4.30343  72.64568  1.000 66.33125  ? 50  SER A C   1 
ATOM   368  O O   . SER A 1 50  ? -54.76958 -3.48438  72.72254  1.000 75.85208  ? 50  SER A O   1 
ATOM   369  C CB  . SER A 1 50  ? -57.54595 -3.77205  74.24279  1.000 46.56595  ? 50  SER A CB  1 
ATOM   370  O OG  . SER A 1 50  ? -58.34182 -4.25789  75.30752  1.000 44.56271  ? 50  SER A OG  1 
ATOM   371  N N   . ILE A 1 51  ? -56.10987 -4.83043  71.49149  1.000 60.98234  ? 51  ILE A N   1 
ATOM   372  C CA  . ILE A 1 51  ? -55.56791 -4.42344  70.20021  1.000 64.45685  ? 51  ILE A CA  1 
ATOM   373  C C   . ILE A 1 51  ? -56.70944 -4.11330  69.24587  1.000 60.37203  ? 51  ILE A C   1 
ATOM   374  O O   . ILE A 1 51  ? -57.79991 -4.68480  69.33587  1.000 62.30076  ? 51  ILE A O   1 
ATOM   375  C CB  . ILE A 1 51  ? -54.64531 -5.49026  69.57882  1.000 65.06439  ? 51  ILE A CB  1 
ATOM   376  C CG1 . ILE A 1 51  ? -55.24712 -6.87840  69.74483  1.000 63.47166  ? 51  ILE A CG1 1 
ATOM   377  C CG2 . ILE A 1 51  ? -53.27094 -5.44254  70.19513  1.000 76.37915  ? 51  ILE A CG2 1 
ATOM   378  C CD1 . ILE A 1 51  ? -54.59047 -7.88055  68.86570  1.000 72.66280  ? 51  ILE A CD1 1 
ATOM   379  N N   . SER A 1 52  ? -56.44519 -3.20683  68.31333  1.000 65.18357  ? 52  SER A N   1 
ATOM   380  C CA  . SER A 1 52  ? -57.47364 -2.78110  67.38160  1.000 69.63305  ? 52  SER A CA  1 
ATOM   381  C C   . SER A 1 52  ? -57.65609 -3.82771  66.28420  1.000 72.32229  ? 52  SER A C   1 
ATOM   382  O O   . SER A 1 52  ? -56.96389 -4.84873  66.22993  1.000 75.52351  ? 52  SER A O   1 
ATOM   383  C CB  . SER A 1 52  ? -57.11299 -1.41995  66.79867  1.000 74.44693  ? 52  SER A CB  1 
ATOM   384  O OG  . SER A 1 52  ? -55.75335 -1.41416  66.40473  1.000 83.98167  ? 52  SER A OG  1 
ATOM   385  N N   . TYR A 1 53  A -58.61330 -3.55966  65.39518  1.000 68.71238  ? 52  TYR A N   1 
ATOM   386  C CA  . TYR A 1 53  A -58.92682 -4.50260  64.32669  1.000 75.61579  ? 52  TYR A CA  1 
ATOM   387  C C   . TYR A 1 53  A -57.74568 -4.72900  63.39445  1.000 72.87528  ? 52  TYR A C   1 
ATOM   388  O O   . TYR A 1 53  A -57.63644 -5.79554  62.77890  1.000 72.92842  ? 52  TYR A O   1 
ATOM   389  C CB  . TYR A 1 53  A -60.12577 -4.00099  63.52678  1.000 83.74253  ? 52  TYR A CB  1 
ATOM   390  C CG  . TYR A 1 53  A -59.78918 -2.84898  62.60825  1.000 87.77765  ? 52  TYR A CG  1 
ATOM   391  C CD1 . TYR A 1 53  A -59.49330 -1.59318  63.12283  1.000 86.19319  ? 52  TYR A CD1 1 
ATOM   392  C CD2 . TYR A 1 53  A -59.77268 -3.01427  61.22720  1.000 86.38995  ? 52  TYR A CD2 1 
ATOM   393  C CE1 . TYR A 1 53  A -59.18526 -0.53906  62.29392  1.000 82.28096  ? 52  TYR A CE1 1 
ATOM   394  C CE2 . TYR A 1 53  A -59.46775 -1.95913  60.38604  1.000 89.51920  ? 52  TYR A CE2 1 
ATOM   395  C CZ  . TYR A 1 53  A -59.17449 -0.72250  60.92650  1.000 85.96934  ? 52  TYR A CZ  1 
ATOM   396  O OH  . TYR A 1 53  A -58.86959 0.33384   60.09762  1.000 95.58110  ? 52  TYR A OH  1 
ATOM   397  N N   . ASP A 1 54  ? -56.86497 -3.74763  63.26044  1.000 71.07038  ? 53  ASP A N   1 
ATOM   398  C CA  . ASP A 1 54  ? -55.71955 -3.88155  62.37946  1.000 79.97797  ? 53  ASP A CA  1 
ATOM   399  C C   . ASP A 1 54  ? -54.42449 -4.20561  63.11529  1.000 83.07715  ? 53  ASP A C   1 
ATOM   400  O O   . ASP A 1 54  ? -53.36989 -4.23307  62.48010  1.000 99.57877  ? 53  ASP A O   1 
ATOM   401  C CB  . ASP A 1 54  ? -55.54656 -2.59990  61.56150  1.000 85.44439  ? 53  ASP A CB  1 
ATOM   402  C CG  . ASP A 1 54  ? -55.83531 -1.35444  62.37199  1.000 85.28556  ? 53  ASP A CG  1 
ATOM   403  O OD1 . ASP A 1 54  ? -55.77699 -1.43367  63.61864  1.000 87.12269  ? 53  ASP A OD1 1 
ATOM   404  O OD2 . ASP A 1 54  ? -56.12061 -0.30012  61.76277  1.000 86.82251  ? 53  ASP A OD2 1 
ATOM   405  N N   . GLY A 1 55  ? -54.46814 -4.44626  64.42546  1.000 73.95636  ? 54  GLY A N   1 
ATOM   406  C CA  . GLY A 1 55  ? -53.25293 -4.68821  65.17641  1.000 78.09495  ? 54  GLY A CA  1 
ATOM   407  C C   . GLY A 1 55  ? -52.25089 -3.55469  65.19149  1.000 85.65500  ? 54  GLY A C   1 
ATOM   408  O O   . GLY A 1 55  ? -51.15662 -3.73637  65.72188  1.000 93.92132  ? 54  GLY A O   1 
ATOM   409  N N   . THR A 1 56  ? -52.58479 -2.39364  64.62858  1.000 80.24812  ? 55  THR A N   1 
ATOM   410  C CA  . THR A 1 56  ? -51.69194 -1.24590  64.67630  1.000 89.92660  ? 55  THR A CA  1 
ATOM   411  C C   . THR A 1 56  ? -51.57291 -0.72738  66.10177  1.000 98.19321  ? 55  THR A C   1 
ATOM   412  O O   . THR A 1 56  ? -50.49537 -0.77467  66.70224  1.000 102.83604 ? 55  THR A O   1 
ATOM   413  C CB  . THR A 1 56  ? -52.21574 -0.14736  63.75554  1.000 91.70397  ? 55  THR A CB  1 
ATOM   414  O OG1 . THR A 1 56  ? -53.48269 0.33830   64.23492  1.000 84.51507  ? 55  THR A OG1 1 
ATOM   415  C CG2 . THR A 1 56  ? -52.41802 -0.68733  62.34988  1.000 96.69183  ? 55  THR A CG2 1 
ATOM   416  N N   . SER A 1 57  ? -52.67491 -0.22569  66.64544  1.000 94.08045  ? 56  SER A N   1 
ATOM   417  C CA  . SER A 1 57  ? -52.68025 0.25973   68.01171  1.000 92.46237  ? 56  SER A CA  1 
ATOM   418  C C   . SER A 1 57  ? -52.80665 -0.90407  68.98253  1.000 80.98391  ? 56  SER A C   1 
ATOM   419  O O   . SER A 1 57  ? -53.47173 -1.90461  68.70951  1.000 75.85175  ? 56  SER A O   1 
ATOM   420  C CB  . SER A 1 57  ? -53.81598 1.26110   68.22420  1.000 92.60232  ? 56  SER A CB  1 
ATOM   421  O OG  . SER A 1 57  ? -55.02180 0.78363   67.66143  1.000 91.84268  ? 56  SER A OG  1 
ATOM   422  N N   . GLN A 1 58  ? -52.14421 -0.76499  70.12339  1.000 76.00785  ? 57  GLN A N   1 
ATOM   423  C CA  . GLN A 1 58  ? -52.08351 -1.83871  71.10710  1.000 70.48336  ? 57  GLN A CA  1 
ATOM   424  C C   . GLN A 1 58  ? -51.80613 -1.18676  72.45203  1.000 83.12721  ? 57  GLN A C   1 
ATOM   425  O O   . GLN A 1 58  ? -50.69150 -0.70968  72.68378  1.000 90.20251  ? 57  GLN A O   1 
ATOM   426  C CB  . GLN A 1 58  ? -50.99677 -2.83882  70.73955  1.000 67.87755  ? 57  GLN A CB  1 
ATOM   427  C CG  . GLN A 1 58  ? -49.69256 -2.18721  70.29610  1.000 82.90848  ? 57  GLN A CG  1 
ATOM   428  C CD  . GLN A 1 58  ? -48.55624 -3.17651  70.19376  1.000 83.72439  ? 57  GLN A CD  1 
ATOM   429  O OE1 . GLN A 1 58  ? -47.98192 -3.58441  71.20468  1.000 87.67308  ? 57  GLN A OE1 1 
ATOM   430  N NE2 . GLN A 1 58  ? -48.22529 -3.57435  68.97216  1.000 76.40462  ? 57  GLN A NE2 1 
ATOM   431  N N   . TYR A 1 59  ? -52.80216 -1.15294  73.33260  1.000 78.83952  ? 58  TYR A N   1 
ATOM   432  C CA  . TYR A 1 59  ? -52.68061 -0.38028  74.56303  1.000 77.20263  ? 58  TYR A CA  1 
ATOM   433  C C   . TYR A 1 59  ? -53.02432 -1.23898  75.77429  1.000 67.47406  ? 58  TYR A C   1 
ATOM   434  O O   . TYR A 1 59  ? -54.05686 -1.91752  75.78841  1.000 60.26502  ? 58  TYR A O   1 
ATOM   435  C CB  . TYR A 1 59  ? -53.55274 0.87823   74.46824  1.000 77.47729  ? 58  TYR A CB  1 
ATOM   436  C CG  . TYR A 1 59  ? -53.11164 1.75103   73.30477  1.000 112.45582 ? 58  TYR A CG  1 
ATOM   437  C CD1 . TYR A 1 59  ? -51.76460 2.06728   73.12246  1.000 128.92253 ? 58  TYR A CD1 1 
ATOM   438  C CD2 . TYR A 1 59  ? -54.02090 2.20567   72.35972  1.000 104.76548 ? 58  TYR A CD2 1 
ATOM   439  C CE1 . TYR A 1 59  ? -51.34507 2.83798   72.05372  1.000 119.98029 ? 58  TYR A CE1 1 
ATOM   440  C CE2 . TYR A 1 59  ? -53.61557 2.97484   71.28866  1.000 120.65806 ? 58  TYR A CE2 1 
ATOM   441  C CZ  . TYR A 1 59  ? -52.27490 3.28828   71.14007  1.000 126.16772 ? 58  TYR A CZ  1 
ATOM   442  O OH  . TYR A 1 59  ? -51.85713 4.05491   70.07779  1.000 114.31274 ? 58  TYR A OH  1 
ATOM   443  N N   . TYR A 1 60  ? -52.14894 -1.19471  76.78664  1.000 72.99720  ? 59  TYR A N   1 
ATOM   444  C CA  . TYR A 1 60  ? -52.09301 -2.11701  77.92068  1.000 69.16914  ? 59  TYR A CA  1 
ATOM   445  C C   . TYR A 1 60  ? -52.47873 -1.41948  79.22426  1.000 72.52378  ? 59  TYR A C   1 
ATOM   446  O O   . TYR A 1 60  ? -52.61569 -0.19274  79.29069  1.000 68.35444  ? 59  TYR A O   1 
ATOM   447  C CB  . TYR A 1 60  ? -50.68352 -2.70843  78.09455  1.000 67.18160  ? 59  TYR A CB  1 
ATOM   448  C CG  . TYR A 1 60  ? -50.06276 -3.35685  76.87582  1.000 69.09016  ? 59  TYR A CG  1 
ATOM   449  C CD1 . TYR A 1 60  ? -49.43084 -2.59118  75.90504  1.000 76.21825  ? 59  TYR A CD1 1 
ATOM   450  C CD2 . TYR A 1 60  ? -50.06584 -4.73719  76.71629  1.000 72.53460  ? 59  TYR A CD2 1 
ATOM   451  C CE1 . TYR A 1 60  ? -48.84997 -3.17918  74.78703  1.000 76.27066  ? 59  TYR A CE1 1 
ATOM   452  C CE2 . TYR A 1 60  ? -49.48099 -5.33808  75.59999  1.000 72.03944  ? 59  TYR A CE2 1 
ATOM   453  C CZ  . TYR A 1 60  ? -48.87619 -4.55063  74.63976  1.000 73.02309  ? 59  TYR A CZ  1 
ATOM   454  O OH  . TYR A 1 60  ? -48.29614 -5.12725  73.53145  1.000 72.93952  ? 59  TYR A OH  1 
ATOM   455  N N   . ALA A 1 61  ? -52.61172 -2.22947  80.27954  1.000 76.58395  ? 60  ALA A N   1 
ATOM   456  C CA  . ALA A 1 61  ? -52.73459 -1.75016  81.65175  1.000 82.66943  ? 60  ALA A CA  1 
ATOM   457  C C   . ALA A 1 61  ? -51.35299 -1.56166  82.26948  1.000 93.97638  ? 60  ALA A C   1 
ATOM   458  O O   . ALA A 1 61  ? -50.39131 -2.25131  81.91508  1.000 96.02508  ? 60  ALA A O   1 
ATOM   459  C CB  . ALA A 1 61  ? -53.54798 -2.71802  82.51407  1.000 68.11049  ? 60  ALA A CB  1 
ATOM   460  N N   . GLU A 1 62  ? -51.27210 -0.63074  83.22507  1.000 90.35174  ? 61  GLU A N   1 
ATOM   461  C CA  . GLU A 1 62  ? -49.97687 -0.22041  83.76375  1.000 95.64474  ? 61  GLU A CA  1 
ATOM   462  C C   . GLU A 1 62  ? -49.30599 -1.33954  84.55186  1.000 97.22403  ? 61  GLU A C   1 
ATOM   463  O O   . GLU A 1 62  ? -48.08440 -1.52152  84.46431  1.000 100.67019 ? 61  GLU A O   1 
ATOM   464  C CB  . GLU A 1 62  ? -50.15310 1.02445   84.63241  1.000 93.53938  ? 61  GLU A CB  1 
ATOM   465  C CG  . GLU A 1 62  ? -48.85482 1.72504   85.01083  1.000 107.10272 ? 61  GLU A CG  1 
ATOM   466  C CD  . GLU A 1 62  ? -47.94052 2.00445   83.82851  1.000 116.36070 ? 61  GLU A CD  1 
ATOM   467  O OE1 . GLU A 1 62  ? -48.37423 2.67250   82.86299  1.000 123.14275 ? 61  GLU A OE1 1 
ATOM   468  O OE2 . GLU A 1 62  ? -46.77393 1.55466   83.87518  1.000 115.95599 ? 61  GLU A OE2 1 
ATOM   469  N N   . SER A 1 63  ? -50.08692 -2.10510  85.31881  1.000 100.43633 ? 62  SER A N   1 
ATOM   470  C CA  . SER A 1 63  ? -49.50045 -3.09632  86.21737  1.000 108.02786 ? 62  SER A CA  1 
ATOM   471  C C   . SER A 1 63  ? -48.74598 -4.17546  85.45257  1.000 94.68940  ? 62  SER A C   1 
ATOM   472  O O   . SER A 1 63  ? -47.82414 -4.79731  85.99562  1.000 98.26657  ? 62  SER A O   1 
ATOM   473  C CB  . SER A 1 63  ? -50.59211 -3.72021  87.08843  1.000 110.95034 ? 62  SER A CB  1 
ATOM   474  O OG  . SER A 1 63  ? -51.80519 -3.86094  86.37025  1.000 103.28037 ? 62  SER A OG  1 
ATOM   475  N N   . VAL A 1 64  ? -49.08901 -4.38036  84.18464  1.000 81.96974  ? 63  VAL A N   1 
ATOM   476  C CA  . VAL A 1 64  ? -48.55547 -5.47916  83.39895  1.000 85.44889  ? 63  VAL A CA  1 
ATOM   477  C C   . VAL A 1 64  ? -47.75083 -4.98654  82.20474  1.000 94.82111  ? 63  VAL A C   1 
ATOM   478  O O   . VAL A 1 64  ? -47.24226 -5.80203  81.42952  1.000 94.65150  ? 63  VAL A O   1 
ATOM   479  C CB  . VAL A 1 64  ? -49.70241 -6.41433  82.95632  1.000 89.98111  ? 63  VAL A CB  1 
ATOM   480  C CG1 . VAL A 1 64  ? -50.67255 -5.68785  82.01054  1.000 84.44977  ? 63  VAL A CG1 1 
ATOM   481  C CG2 . VAL A 1 64  ? -49.21450 -7.75488  82.43535  1.000 86.55063  ? 63  VAL A CG2 1 
ATOM   482  N N   . LYS A 1 65  ? -47.60551 -3.67205  82.04730  1.000 97.08956  ? 64  LYS A N   1 
ATOM   483  C CA  . LYS A 1 65  ? -46.87511 -3.11331  80.91937  1.000 96.05542  ? 64  LYS A CA  1 
ATOM   484  C C   . LYS A 1 65  ? -45.44281 -3.62460  80.89901  1.000 91.19727  ? 64  LYS A C   1 
ATOM   485  O O   . LYS A 1 65  ? -44.78603 -3.72124  81.93739  1.000 89.58961  ? 64  LYS A O   1 
ATOM   486  C CB  . LYS A 1 65  ? -46.88323 -1.58927  81.01056  1.000 105.57061 ? 64  LYS A CB  1 
ATOM   487  C CG  . LYS A 1 65  ? -46.67920 -0.85021  79.70029  1.000 106.58269 ? 64  LYS A CG  1 
ATOM   488  C CD  . LYS A 1 65  ? -47.35780 0.51309   79.77481  1.000 109.11444 ? 64  LYS A CD  1 
ATOM   489  C CE  . LYS A 1 65  ? -47.51030 1.15210   78.40427  1.000 114.92507 ? 64  LYS A CE  1 
ATOM   490  N NZ  . LYS A 1 65  ? -48.68624 2.06970   78.34502  1.000 101.10866 ? 64  LYS A NZ  1 
ATOM   491  N N   . GLY A 1 66  ? -44.95835 -3.95421  79.70587  1.000 93.29887  ? 65  GLY A N   1 
ATOM   492  C CA  . GLY A 1 66  ? -43.57910 -4.37191  79.56125  1.000 98.81188  ? 65  GLY A CA  1 
ATOM   493  C C   . GLY A 1 66  ? -43.39506 -5.87396  79.58204  1.000 91.26206  ? 65  GLY A C   1 
ATOM   494  O O   . GLY A 1 66  ? -42.96872 -6.46593  78.58525  1.000 89.00526  ? 65  GLY A O   1 
ATOM   495  N N   . ARG A 1 67  ? -43.72056 -6.50190  80.71486  1.000 85.06251  ? 66  ARG A N   1 
ATOM   496  C CA  . ARG A 1 67  ? -43.59369 -7.94946  80.83947  1.000 84.08209  ? 66  ARG A CA  1 
ATOM   497  C C   . ARG A 1 67  ? -44.51432 -8.69228  79.87569  1.000 88.26325  ? 66  ARG A C   1 
ATOM   498  O O   . ARG A 1 67  ? -44.31526 -9.89141  79.64500  1.000 87.95585  ? 66  ARG A O   1 
ATOM   499  C CB  . ARG A 1 67  ? -43.87253 -8.36813  82.29318  1.000 80.48380  ? 66  ARG A CB  1 
ATOM   500  C CG  . ARG A 1 67  ? -43.10666 -7.52572  83.32158  1.000 82.44968  ? 66  ARG A CG  1 
ATOM   501  C CD  . ARG A 1 67  ? -43.08849 -8.09803  84.74866  1.000 86.96400  ? 66  ARG A CD  1 
ATOM   502  N NE  . ARG A 1 67  ? -44.40628 -8.25100  85.35276  1.000 82.48728  ? 66  ARG A NE  1 
ATOM   503  C CZ  . ARG A 1 67  ? -44.99943 -9.41708  85.56980  1.000 85.14957  ? 66  ARG A CZ  1 
ATOM   504  N NH1 . ARG A 1 67  ? -44.41820 -10.55895 85.24217  1.000 90.74931  ? 66  ARG A NH1 1 
ATOM   505  N NH2 . ARG A 1 67  ? -46.20171 -9.43804  86.14004  1.000 81.75760  ? 66  ARG A NH2 1 
ATOM   506  N N   . PHE A 1 68  ? -45.49842 -8.00403  79.29165  1.000 81.84669  ? 67  PHE A N   1 
ATOM   507  C CA  . PHE A 1 68  ? -46.49698 -8.60688  78.41988  1.000 77.13731  ? 67  PHE A CA  1 
ATOM   508  C C   . PHE A 1 68  ? -46.50159 -7.90577  77.06795  1.000 75.49054  ? 67  PHE A C   1 
ATOM   509  O O   . PHE A 1 68  ? -46.28196 -6.69473  76.98033  1.000 81.54201  ? 67  PHE A O   1 
ATOM   510  C CB  . PHE A 1 68  ? -47.90048 -8.51127  79.03095  1.000 77.82510  ? 67  PHE A CB  1 
ATOM   511  C CG  . PHE A 1 68  ? -48.26054 -9.65681  79.93475  1.000 84.60476  ? 67  PHE A CG  1 
ATOM   512  C CD1 . PHE A 1 68  ? -47.32827 -10.19808 80.80222  1.000 94.52117  ? 67  PHE A CD1 1 
ATOM   513  C CD2 . PHE A 1 68  ? -49.54884 -10.16926 79.94030  1.000 82.26038  ? 67  PHE A CD2 1 
ATOM   514  C CE1 . PHE A 1 68  ? -47.66638 -11.23949 81.64536  1.000 93.93028  ? 67  PHE A CE1 1 
ATOM   515  C CE2 . PHE A 1 68  ? -49.89293 -11.21181 80.77966  1.000 82.95430  ? 67  PHE A CE2 1 
ATOM   516  C CZ  . PHE A 1 68  ? -48.94946 -11.74785 81.63399  1.000 90.83720  ? 67  PHE A CZ  1 
ATOM   517  N N   . THR A 1 69  ? -46.75129 -8.67758  76.01054  1.000 68.83535  ? 68  THR A N   1 
ATOM   518  C CA  . THR A 1 69  ? -46.95535 -8.13455  74.67202  1.000 63.66888  ? 68  THR A CA  1 
ATOM   519  C C   . THR A 1 69  ? -48.05622 -8.92697  73.98634  1.000 62.10403  ? 68  THR A C   1 
ATOM   520  O O   . THR A 1 69  ? -48.06749 -10.15981 74.04564  1.000 62.99975  ? 68  THR A O   1 
ATOM   521  C CB  . THR A 1 69  ? -45.67680 -8.17707  73.81804  1.000 69.13444  ? 68  THR A CB  1 
ATOM   522  O OG1 . THR A 1 69  ? -45.34292 -9.53720  73.51233  1.000 85.42469  ? 68  THR A OG1 1 
ATOM   523  C CG2 . THR A 1 69  ? -44.50159 -7.48853  74.51190  1.000 53.65698  ? 68  THR A CG2 1 
ATOM   524  N N   . VAL A 1 70  ? -48.97535 -8.22154  73.33894  1.000 59.27728  ? 69  VAL A N   1 
ATOM   525  C CA  . VAL A 1 70  ? -50.09310 -8.83959  72.64180  1.000 57.94330  ? 69  VAL A CA  1 
ATOM   526  C C   . VAL A 1 70  ? -49.87189 -8.69288  71.14456  1.000 60.97256  ? 69  VAL A C   1 
ATOM   527  O O   . VAL A 1 70  ? -49.44040 -7.63578  70.67021  1.000 67.20173  ? 69  VAL A O   1 
ATOM   528  C CB  . VAL A 1 70  ? -51.42688 -8.20522  73.06675  1.000 49.77606  ? 69  VAL A CB  1 
ATOM   529  C CG1 . VAL A 1 70  ? -51.33286 -6.70603  72.94651  1.000 53.91885  ? 69  VAL A CG1 1 
ATOM   530  C CG2 . VAL A 1 70  ? -52.55316 -8.73911  72.21980  1.000 47.59569  ? 69  VAL A CG2 1 
ATOM   531  N N   . SER A 1 71  ? -50.16821 -9.75512  70.40037  1.000 64.78836  ? 70  SER A N   1 
ATOM   532  C CA  . SER A 1 71  ? -49.96869 -9.77260  68.95909  1.000 75.14806  ? 70  SER A CA  1 
ATOM   533  C C   . SER A 1 71  ? -51.15835 -10.45242 68.29573  1.000 78.02371  ? 70  SER A C   1 
ATOM   534  O O   . SER A 1 71  ? -51.96422 -11.11472 68.95362  1.000 79.23349  ? 70  SER A O   1 
ATOM   535  C CB  . SER A 1 71  ? -48.66707 -10.49004 68.59339  1.000 84.28494  ? 70  SER A CB  1 
ATOM   536  O OG  . SER A 1 71  ? -48.54840 -11.70686 69.30943  1.000 81.99459  ? 70  SER A OG  1 
ATOM   537  N N   . ARG A 1 72  ? -51.25815 -10.30444 66.97350  1.000 74.85068  ? 71  ARG A N   1 
ATOM   538  C CA  . ARG A 1 72  ? -52.38703 -10.87627 66.24526  1.000 75.50134  ? 71  ARG A CA  1 
ATOM   539  C C   . ARG A 1 72  ? -51.99342 -11.14977 64.80113  1.000 92.84758  ? 71  ARG A C   1 
ATOM   540  O O   . ARG A 1 72  ? -51.39070 -10.29040 64.15085  1.000 104.78221 ? 71  ARG A O   1 
ATOM   541  C CB  . ARG A 1 72  ? -53.59556 -9.93581  66.29096  1.000 69.46789  ? 71  ARG A CB  1 
ATOM   542  C CG  . ARG A 1 72  ? -54.80729 -10.41741 65.49919  1.000 75.18306  ? 71  ARG A CG  1 
ATOM   543  C CD  . ARG A 1 72  ? -55.67168 -9.25149  65.01938  1.000 74.75185  ? 71  ARG A CD  1 
ATOM   544  N NE  . ARG A 1 72  ? -56.34070 -8.55758  66.11538  1.000 58.71335  ? 71  ARG A NE  1 
ATOM   545  C CZ  . ARG A 1 72  ? -57.43421 -7.81806  65.98311  1.000 57.35574  ? 71  ARG A CZ  1 
ATOM   546  N NH1 . ARG A 1 72  ? -58.03318 -7.67239  64.81319  1.000 63.86133  ? 71  ARG A NH1 1 
ATOM   547  N NH2 . ARG A 1 72  ? -57.94150 -7.21200  67.05316  1.000 58.94977  ? 71  ARG A NH2 1 
ATOM   548  N N   . ASP A 1 73  ? -52.34811 -12.33506 64.29973  1.000 91.73186  ? 72  ASP A N   1 
ATOM   549  C CA  . ASP A 1 73  ? -52.16698 -12.69616 62.89413  1.000 98.16876  ? 72  ASP A CA  1 
ATOM   550  C C   . ASP A 1 73  ? -53.55358 -12.79475 62.26311  1.000 89.58689  ? 72  ASP A C   1 
ATOM   551  O O   . ASP A 1 73  ? -54.24500 -13.80640 62.41313  1.000 84.04636  ? 72  ASP A O   1 
ATOM   552  C CB  . ASP A 1 73  ? -51.39241 -14.00615 62.75089  1.000 98.72434  ? 72  ASP A CB  1 
ATOM   553  C CG  . ASP A 1 73  ? -50.83554 -14.21270 61.34531  1.000 107.61937 ? 72  ASP A CG  1 
ATOM   554  O OD1 . ASP A 1 73  ? -51.01196 -13.32011 60.47799  1.000 107.17662 ? 72  ASP A OD1 1 
ATOM   555  O OD2 . ASP A 1 73  ? -50.22624 -15.28067 61.10932  1.000 110.33088 ? 72  ASP A OD2 1 
ATOM   556  N N   . ASN A 1 74  ? -53.95671 -11.74154 61.55028  1.000 91.29455  ? 73  ASN A N   1 
ATOM   557  C CA  . ASN A 1 74  ? -55.26801 -11.73778 60.91385  1.000 93.63730  ? 73  ASN A CA  1 
ATOM   558  C C   . ASN A 1 74  ? -55.34914 -12.71436 59.74586  1.000 102.32519 ? 73  ASN A C   1 
ATOM   559  O O   . ASN A 1 74  ? -56.45638 -13.09237 59.34321  1.000 95.40948  ? 73  ASN A O   1 
ATOM   560  C CB  . ASN A 1 74  ? -55.61798 -10.32188 60.44862  1.000 95.39861  ? 73  ASN A CB  1 
ATOM   561  C CG  . ASN A 1 74  ? -56.67189 -9.66499  61.32586  1.000 86.31625  ? 73  ASN A CG  1 
ATOM   562  O OD1 . ASN A 1 74  ? -57.11208 -10.24493 62.31712  1.000 84.97439  ? 73  ASN A OD1 1 
ATOM   563  N ND2 . ASN A 1 74  ? -57.08248 -8.45264  60.96332  1.000 83.77891  ? 73  ASN A ND2 1 
ATOM   564  N N   . SER A 1 75  ? -54.20463 -13.12851 59.19578  1.000 109.17179 ? 74  SER A N   1 
ATOM   565  C CA  . SER A 1 75  ? -54.21195 -14.10995 58.11583  1.000 108.14640 ? 74  SER A CA  1 
ATOM   566  C C   . SER A 1 75  ? -54.52958 -15.50465 58.64085  1.000 99.68336  ? 74  SER A C   1 
ATOM   567  O O   . SER A 1 75  ? -55.26524 -16.26352 57.99904  1.000 96.78272  ? 74  SER A O   1 
ATOM   568  C CB  . SER A 1 75  ? -52.86543 -14.09803 57.38665  1.000 117.87017 ? 74  SER A CB  1 
ATOM   569  O OG  . SER A 1 75  ? -51.90337 -14.90577 58.04618  1.000 115.93724 ? 74  SER A OG  1 
ATOM   570  N N   . LYS A 1 76  ? -53.98639 -15.85794 59.80484  1.000 95.63805  ? 75  LYS A N   1 
ATOM   571  C CA  . LYS A 1 76  ? -54.22245 -17.15970 60.41314  1.000 94.76218  ? 75  LYS A CA  1 
ATOM   572  C C   . LYS A 1 76  ? -55.36930 -17.14829 61.41791  1.000 86.09174  ? 75  LYS A C   1 
ATOM   573  O O   . LYS A 1 76  ? -55.73862 -18.21611 61.91858  1.000 79.09777  ? 75  LYS A O   1 
ATOM   574  C CB  . LYS A 1 76  ? -52.94151 -17.66526 61.09211  1.000 95.39997  ? 75  LYS A CB  1 
ATOM   575  C CG  . LYS A 1 76  ? -52.34625 -18.93584 60.46961  1.000 105.28050 ? 75  LYS A CG  1 
ATOM   576  C CD  . LYS A 1 76  ? -51.97432 -18.74147 58.99924  1.000 101.84106 ? 75  LYS A CD  1 
ATOM   577  C CE  . LYS A 1 76  ? -51.34224 -19.99980 58.40339  1.000 89.47037  ? 75  LYS A CE  1 
ATOM   578  N NZ  . LYS A 1 76  ? -50.95071 -19.83263 56.97142  1.000 70.35292  ? 75  LYS A NZ  1 
ATOM   579  N N   . LYS A 1 77  ? -55.91681 -15.97176 61.73802  1.000 88.25731  ? 76  LYS A N   1 
ATOM   580  C CA  . LYS A 1 77  ? -57.13782 -15.83629 62.54115  1.000 82.69709  ? 76  LYS A CA  1 
ATOM   581  C C   . LYS A 1 77  ? -56.92533 -16.22938 64.00646  1.000 76.42835  ? 76  LYS A C   1 
ATOM   582  O O   . LYS A 1 77  ? -57.75496 -16.92236 64.59710  1.000 67.81410  ? 76  LYS A O   1 
ATOM   583  C CB  . LYS A 1 77  ? -58.28886 -16.64468 61.93336  1.000 75.98824  ? 76  LYS A CB  1 
ATOM   584  C CG  . LYS A 1 77  ? -59.00432 -15.96492 60.78128  1.000 77.73924  ? 76  LYS A CG  1 
ATOM   585  C CD  . LYS A 1 77  ? -60.50746 -15.98209 61.01544  1.000 87.49581  ? 76  LYS A CD  1 
ATOM   586  C CE  . LYS A 1 77  ? -61.25869 -15.22352 59.92996  1.000 85.12383  ? 76  LYS A CE  1 
ATOM   587  N NZ  . LYS A 1 77  ? -62.73337 -15.21397 60.16578  1.000 78.04085  ? 76  LYS A NZ  1 
ATOM   588  N N   . THR A 1 78  ? -55.82488 -15.77413 64.60861  1.000 74.17291  ? 77  THR A N   1 
ATOM   589  C CA  . THR A 1 78  ? -55.56080 -16.03451 66.01970  1.000 62.29026  ? 77  THR A CA  1 
ATOM   590  C C   . THR A 1 78  ? -55.05360 -14.77201 66.70492  1.000 61.50150  ? 77  THR A C   1 
ATOM   591  O O   . THR A 1 78  ? -54.61319 -13.81657 66.05959  1.000 65.65405  ? 77  THR A O   1 
ATOM   592  C CB  . THR A 1 78  ? -54.53883 -17.16744 66.23410  1.000 69.88006  ? 77  THR A CB  1 
ATOM   593  O OG1 . THR A 1 78  ? -53.20905 -16.65703 66.07500  1.000 75.93640  ? 77  THR A OG1 1 
ATOM   594  C CG2 . THR A 1 78  ? -54.76768 -18.32516 65.26502  1.000 76.69896  ? 77  THR A CG2 1 
ATOM   595  N N   . LEU A 1 79  ? -55.11689 -14.79443 68.03701  1.000 66.85957  ? 78  LEU A N   1 
ATOM   596  C CA  . LEU A 1 79  ? -54.65692 -13.71045 68.89956  1.000 68.41875  ? 78  LEU A CA  1 
ATOM   597  C C   . LEU A 1 79  ? -53.69032 -14.27755 69.92579  1.000 66.70845  ? 78  LEU A C   1 
ATOM   598  O O   . LEU A 1 79  ? -54.02287 -15.24503 70.61390  1.000 66.87588  ? 78  LEU A O   1 
ATOM   599  C CB  . LEU A 1 79  ? -55.82614 -13.03751 69.62578  1.000 60.70537  ? 78  LEU A CB  1 
ATOM   600  C CG  . LEU A 1 79  ? -55.41975 -12.26296 70.88456  1.000 56.10249  ? 78  LEU A CG  1 
ATOM   601  C CD1 . LEU A 1 79  ? -54.72175 -10.96780 70.51713  1.000 60.65172  ? 78  LEU A CD1 1 
ATOM   602  C CD2 . LEU A 1 79  ? -56.59417 -12.00305 71.80782  1.000 55.78390  ? 78  LEU A CD2 1 
ATOM   603  N N   . LEU A 1 80  ? -52.51753 -13.66217 70.05561  1.000 65.29832  ? 79  LEU A N   1 
ATOM   604  C CA  . LEU A 1 80  ? -51.44751 -14.19382 70.88735  1.000 62.64381  ? 79  LEU A CA  1 
ATOM   605  C C   . LEU A 1 80  ? -51.10708 -13.23593 72.01909  1.000 60.84380  ? 79  LEU A C   1 
ATOM   606  O O   . LEU A 1 80  ? -51.14843 -12.01350 71.84954  1.000 63.13129  ? 79  LEU A O   1 
ATOM   607  C CB  . LEU A 1 80  ? -50.19151 -14.46511 70.05398  1.000 75.26616  ? 79  LEU A CB  1 
ATOM   608  C CG  . LEU A 1 80  ? -49.14238 -15.40371 70.65419  1.000 83.62549  ? 79  LEU A CG  1 
ATOM   609  C CD1 . LEU A 1 80  ? -48.68218 -16.44370 69.63015  1.000 95.56603  ? 79  LEU A CD1 1 
ATOM   610  C CD2 . LEU A 1 80  ? -47.96442 -14.61132 71.20635  1.000 76.38211  ? 79  LEU A CD2 1 
ATOM   611  N N   . LEU A 1 81  ? -50.76099 -13.81000 73.16985  1.000 63.94519  ? 80  LEU A N   1 
ATOM   612  C CA  . LEU A 1 81  ? -50.25017 -13.07359 74.32052  1.000 64.71763  ? 80  LEU A CA  1 
ATOM   613  C C   . LEU A 1 81  ? -49.02763 -13.80342 74.84918  1.000 66.48235  ? 80  LEU A C   1 
ATOM   614  O O   . LEU A 1 81  ? -49.13159 -14.95547 75.28272  1.000 67.87461  ? 80  LEU A O   1 
ATOM   615  C CB  . LEU A 1 81  ? -51.30361 -12.94613 75.42269  1.000 57.89278  ? 80  LEU A CB  1 
ATOM   616  C CG  . LEU A 1 81  ? -50.77816 -12.38612 76.74408  1.000 50.31052  ? 80  LEU A CG  1 
ATOM   617  C CD1 . LEU A 1 81  ? -50.31707 -10.96220 76.56351  1.000 60.97608  ? 80  LEU A CD1 1 
ATOM   618  C CD2 . LEU A 1 81  ? -51.82602 -12.48020 77.83755  1.000 42.62966  ? 80  LEU A CD2 1 
ATOM   619  N N   . GLN A 1 82  ? -47.87713 -13.14223 74.80971  1.000 67.51096  ? 81  GLN A N   1 
ATOM   620  C CA  . GLN A 1 82  ? -46.64214 -13.71449 75.32160  1.000 77.81898  ? 81  GLN A CA  1 
ATOM   621  C C   . GLN A 1 82  ? -46.37229 -13.19809 76.72749  1.000 75.93098  ? 81  GLN A C   1 
ATOM   622  O O   . GLN A 1 82  ? -46.52588 -12.00506 77.00461  1.000 72.08264  ? 81  GLN A O   1 
ATOM   623  C CB  . GLN A 1 82  ? -45.45716 -13.39020 74.40932  1.000 90.89231  ? 81  GLN A CB  1 
ATOM   624  C CG  . GLN A 1 82  ? -44.23991 -14.26695 74.67914  1.000 94.86779  ? 81  GLN A CG  1 
ATOM   625  C CD  . GLN A 1 82  ? -43.06700 -13.95810 73.76958  1.000 99.82660  ? 81  GLN A CD  1 
ATOM   626  O OE1 . GLN A 1 82  ? -43.06157 -12.94997 73.06503  1.000 99.54330  ? 81  GLN A OE1 1 
ATOM   627  N NE2 . GLN A 1 82  ? -42.06204 -14.82814 73.78351  1.000 105.49864 ? 81  GLN A NE2 1 
ATOM   628  N N   . VAL A 1 83  ? -45.96237 -14.10464 77.60842  1.000 80.88360  ? 82  VAL A N   1 
ATOM   629  C CA  . VAL A 1 83  ? -45.68436 -13.79285 79.00448  1.000 81.73513  ? 82  VAL A CA  1 
ATOM   630  C C   . VAL A 1 83  ? -44.19350 -13.97196 79.24405  1.000 89.26952  ? 82  VAL A C   1 
ATOM   631  O O   . VAL A 1 83  ? -43.66053 -15.07121 79.06287  1.000 92.40069  ? 82  VAL A O   1 
ATOM   632  C CB  . VAL A 1 83  ? -46.49931 -14.68554 79.95066  1.000 76.41276  ? 82  VAL A CB  1 
ATOM   633  C CG1 . VAL A 1 83  ? -46.18335 -14.34956 81.38957  1.000 82.44379  ? 82  VAL A CG1 1 
ATOM   634  C CG2 . VAL A 1 83  ? -47.98099 -14.53386 79.67226  1.000 77.59938  ? 82  VAL A CG2 1 
ATOM   635  N N   . ASN A 1 84  A -43.52256 -12.90304 79.65935  1.000 87.82376  ? 83  ASN A N   1 
ATOM   636  C CA  . ASN A 1 84  A -42.11569 -12.95605 80.02734  1.000 88.85471  ? 83  ASN A CA  1 
ATOM   637  C C   . ASN A 1 84  A -41.96251 -12.68247 81.51612  1.000 83.30933  ? 83  ASN A C   1 
ATOM   638  O O   . ASN A 1 84  A -42.69888 -11.87062 82.08737  1.000 79.48164  ? 83  ASN A O   1 
ATOM   639  C CB  . ASN A 1 84  A -41.28915 -11.94363 79.22709  1.000 99.53462  ? 83  ASN A CB  1 
ATOM   640  C CG  . ASN A 1 84  A -41.34481 -12.18933 77.72746  1.000 101.08945 ? 83  ASN A CG  1 
ATOM   641  O OD1 . ASN A 1 84  A -41.75311 -13.25782 77.27257  1.000 100.42752 ? 83  ASN A OD1 1 
ATOM   642  N ND2 . ASN A 1 84  A -40.93697 -11.19010 76.95110  1.000 92.90093  ? 83  ASN A ND2 1 
ATOM   643  N N   . SER A 1 85  B -41.00453 -13.37411 82.13712  1.000 86.35958  ? 83  SER A N   1 
ATOM   644  C CA  . SER A 1 85  B -40.64702 -13.16282 83.54340  1.000 84.24626  ? 83  SER A CA  1 
ATOM   645  C C   . SER A 1 85  B -41.81731 -13.49555 84.47067  1.000 75.35854  ? 83  SER A C   1 
ATOM   646  O O   . SER A 1 85  B -42.26877 -12.66065 85.25280  1.000 76.97576  ? 83  SER A O   1 
ATOM   647  C CB  . SER A 1 85  B -40.15587 -11.73054 83.77640  1.000 97.52207  ? 83  SER A CB  1 
ATOM   648  O OG  . SER A 1 85  B -39.20016 -11.36665 82.80219  1.000 124.45045 ? 83  SER A OG  1 
ATOM   649  N N   . LEU A 1 86  C -42.29537 -14.73435 84.38188  1.000 74.14279  ? 83  LEU A N   1 
ATOM   650  C CA  . LEU A 1 86  C -43.43885 -15.16772 85.17403  1.000 67.26697  ? 83  LEU A CA  1 
ATOM   651  C C   . LEU A 1 86  C -43.13959 -15.06298 86.66450  1.000 71.04986  ? 83  LEU A C   1 
ATOM   652  O O   . LEU A 1 86  C -42.00957 -15.28941 87.10069  1.000 83.75584  ? 83  LEU A O   1 
ATOM   653  C CB  . LEU A 1 86  C -43.80440 -16.60496 84.80556  1.000 63.24688  ? 83  LEU A CB  1 
ATOM   654  C CG  . LEU A 1 86  C -44.80214 -16.79343 83.66962  1.000 62.41207  ? 83  LEU A CG  1 
ATOM   655  C CD1 . LEU A 1 86  C -44.65260 -18.17078 83.06280  1.000 69.72216  ? 83  LEU A CD1 1 
ATOM   656  C CD2 . LEU A 1 86  C -46.19430 -16.60076 84.22266  1.000 68.36003  ? 83  LEU A CD2 1 
ATOM   657  N N   . ARG A 1 87  ? -44.15862 -14.71824 87.44842  1.000 70.59581  ? 84  ARG A N   1 
ATOM   658  C CA  . ARG A 1 87  ? -44.00843 -14.55322 88.88761  1.000 81.74020  ? 84  ARG A CA  1 
ATOM   659  C C   . ARG A 1 87  ? -45.02907 -15.40024 89.63545  1.000 80.77015  ? 84  ARG A C   1 
ATOM   660  O O   . ARG A 1 87  ? -46.09078 -15.72102 89.09143  1.000 75.74709  ? 84  ARG A O   1 
ATOM   661  C CB  . ARG A 1 87  ? -44.15853 -13.07578 89.29433  1.000 84.76760  ? 84  ARG A CB  1 
ATOM   662  C CG  . ARG A 1 87  ? -42.82671 -12.33811 89.39168  1.000 88.46841  ? 84  ARG A CG  1 
ATOM   663  C CD  . ARG A 1 87  ? -42.90210 -11.10751 90.29178  1.000 99.26247  ? 84  ARG A CD  1 
ATOM   664  N NE  . ARG A 1 87  ? -43.81004 -10.08452 89.78065  1.000 100.82443 ? 84  ARG A NE  1 
ATOM   665  C CZ  . ARG A 1 87  ? -43.47368 -9.17390  88.87684  1.000 98.48412  ? 84  ARG A CZ  1 
ATOM   666  N NH1 . ARG A 1 87  ? -42.26375 -9.14536  88.33998  1.000 91.63091  ? 84  ARG A NH1 1 
ATOM   667  N NH2 . ARG A 1 87  ? -44.37442 -8.27421  88.49728  1.000 99.03212  ? 84  ARG A NH2 1 
ATOM   668  N N   . PRO A 1 88  ? -44.73189 -15.78966 90.88222  1.000 89.45455  ? 85  PRO A N   1 
ATOM   669  C CA  . PRO A 1 88  ? -45.68939 -16.62391 91.62832  1.000 84.44294  ? 85  PRO A CA  1 
ATOM   670  C C   . PRO A 1 88  ? -47.01954 -15.94303 91.86053  1.000 83.69888  ? 85  PRO A C   1 
ATOM   671  O O   . PRO A 1 88  ? -48.00383 -16.62692 92.16384  1.000 87.43960  ? 85  PRO A O   1 
ATOM   672  C CB  . PRO A 1 88  ? -44.96594 -16.90528 92.95428  1.000 98.50063  ? 85  PRO A CB  1 
ATOM   673  C CG  . PRO A 1 88  ? -43.96743 -15.80643 93.08802  1.000 103.74406 ? 85  PRO A CG  1 
ATOM   674  C CD  . PRO A 1 88  ? -43.54307 -15.46012 91.69013  1.000 106.94835 ? 85  PRO A CD  1 
ATOM   675  N N   . GLU A 1 89  ? -47.08284 -14.62304 91.72586  1.000 80.93290  ? 86  GLU A N   1 
ATOM   676  C CA  . GLU A 1 89  ? -48.32266 -13.87904 91.87479  1.000 79.60898  ? 86  GLU A CA  1 
ATOM   677  C C   . GLU A 1 89  ? -49.10259 -13.74883 90.56726  1.000 68.15637  ? 86  GLU A C   1 
ATOM   678  O O   . GLU A 1 89  ? -50.08462 -13.00004 90.52189  1.000 63.28420  ? 86  GLU A O   1 
ATOM   679  C CB  . GLU A 1 89  ? -48.03224 -12.49116 92.45599  1.000 88.04177  ? 86  GLU A CB  1 
ATOM   680  C CG  . GLU A 1 89  ? -47.36078 -12.51238 93.82790  1.000 105.15644 ? 86  GLU A CG  1 
ATOM   681  C CD  . GLU A 1 89  ? -45.84688 -12.60168 93.75243  1.000 115.33730 ? 86  GLU A CD  1 
ATOM   682  O OE1 . GLU A 1 89  ? -45.28389 -12.36511 92.66020  1.000 99.76447  ? 86  GLU A OE1 1 
ATOM   683  O OE2 . GLU A 1 89  ? -45.22013 -12.89922 94.79414  1.000 130.73939 ? 86  GLU A OE2 1 
ATOM   684  N N   . ASP A 1 90  ? -48.69641 -14.45715 89.51140  1.000 66.59258  ? 87  ASP A N   1 
ATOM   685  C CA  . ASP A 1 90  ? -49.36342 -14.39364 88.21502  1.000 59.24160  ? 87  ASP A CA  1 
ATOM   686  C C   . ASP A 1 90  ? -50.29695 -15.56870 87.95915  1.000 54.93149  ? 87  ASP A C   1 
ATOM   687  O O   . ASP A 1 90  ? -50.94290 -15.60492 86.90687  1.000 48.89648  ? 87  ASP A O   1 
ATOM   688  C CB  . ASP A 1 90  ? -48.33092 -14.32859 87.07823  1.000 59.70558  ? 87  ASP A CB  1 
ATOM   689  C CG  . ASP A 1 90  ? -47.50671 -13.05770 87.10035  1.000 79.00426  ? 87  ASP A CG  1 
ATOM   690  O OD1 . ASP A 1 90  ? -47.98817 -12.04053 87.63804  1.000 87.03782  ? 87  ASP A OD1 1 
ATOM   691  O OD2 . ASP A 1 90  ? -46.36727 -13.08796 86.58385  1.000 80.26092  ? 87  ASP A OD2 1 
ATOM   692  N N   . THR A 1 91  ? -50.38431 -16.52211 88.88429  1.000 61.56804  ? 88  THR A N   1 
ATOM   693  C CA  . THR A 1 91  ? -51.15231 -17.74183 88.66310  1.000 54.66397  ? 88  THR A CA  1 
ATOM   694  C C   . THR A 1 91  ? -52.63284 -17.39587 88.59844  1.000 51.97160  ? 88  THR A C   1 
ATOM   695  O O   . THR A 1 91  ? -53.22102 -16.96188 89.59265  1.000 63.41549  ? 88  THR A O   1 
ATOM   696  C CB  . THR A 1 91  ? -50.87387 -18.74606 89.77880  1.000 60.91154  ? 88  THR A CB  1 
ATOM   697  O OG1 . THR A 1 91  ? -51.37161 -18.23027 91.01722  1.000 73.74892  ? 88  THR A OG1 1 
ATOM   698  C CG2 . THR A 1 91  ? -49.38587 -18.95640 89.91847  1.000 70.62835  ? 88  THR A CG2 1 
ATOM   699  N N   . ALA A 1 92  ? -53.24589 -17.60131 87.43941  1.000 50.65985  ? 89  ALA A N   1 
ATOM   700  C CA  . ALA A 1 92  ? -54.64133 -17.22801 87.25583  1.000 56.64074  ? 89  ALA A CA  1 
ATOM   701  C C   . ALA A 1 92  ? -55.19513 -17.91362 86.01337  1.000 57.83512  ? 89  ALA A C   1 
ATOM   702  O O   . ALA A 1 92  ? -54.45576 -18.47808 85.20221  1.000 55.73554  ? 89  ALA A O   1 
ATOM   703  C CB  . ALA A 1 92  ? -54.80157 -15.70821 87.14496  1.000 57.69236  ? 89  ALA A CB  1 
ATOM   704  N N   . VAL A 1 93  ? -56.51993 -17.86404 85.88886  1.000 58.95305  ? 90  VAL A N   1 
ATOM   705  C CA  . VAL A 1 93  ? -57.21234 -18.29275 84.67760  1.000 55.11272  ? 90  VAL A CA  1 
ATOM   706  C C   . VAL A 1 93  ? -57.23001 -17.12189 83.70905  1.000 59.02903  ? 90  VAL A C   1 
ATOM   707  O O   . VAL A 1 93  ? -57.68679 -16.02585 84.05421  1.000 56.29996  ? 90  VAL A O   1 
ATOM   708  C CB  . VAL A 1 93  ? -58.64068 -18.76563 84.98191  1.000 54.39503  ? 90  VAL A CB  1 
ATOM   709  C CG1 . VAL A 1 93  ? -59.31803 -19.25047 83.70358  1.000 55.79200  ? 90  VAL A CG1 1 
ATOM   710  C CG2 . VAL A 1 93  ? -58.62323 -19.85506 86.03978  1.000 71.68189  ? 90  VAL A CG2 1 
ATOM   711  N N   . TYR A 1 94  ? -56.74743 -17.35396 82.49394  1.000 63.32056  ? 91  TYR A N   1 
ATOM   712  C CA  . TYR A 1 94  ? -56.60793 -16.30005 81.50165  1.000 54.05039  ? 91  TYR A CA  1 
ATOM   713  C C   . TYR A 1 94  ? -57.69268 -16.45321 80.44663  1.000 53.20917  ? 91  TYR A C   1 
ATOM   714  O O   . TYR A 1 94  ? -57.81058 -17.50920 79.81252  1.000 54.12745  ? 91  TYR A O   1 
ATOM   715  C CB  . TYR A 1 94  ? -55.21312 -16.32081 80.87342  1.000 51.00111  ? 91  TYR A CB  1 
ATOM   716  C CG  . TYR A 1 94  ? -54.14418 -15.74103 81.78574  1.000 54.01360  ? 91  TYR A CG  1 
ATOM   717  C CD1 . TYR A 1 94  ? -53.84036 -16.33698 83.00040  1.000 58.99126  ? 91  TYR A CD1 1 
ATOM   718  C CD2 . TYR A 1 94  ? -53.46386 -14.57982 81.44699  1.000 56.71513  ? 91  TYR A CD2 1 
ATOM   719  C CE1 . TYR A 1 94  ? -52.88049 -15.80468 83.84454  1.000 57.41124  ? 91  TYR A CE1 1 
ATOM   720  C CE2 . TYR A 1 94  ? -52.49818 -14.03940 82.29104  1.000 58.43195  ? 91  TYR A CE2 1 
ATOM   721  C CZ  . TYR A 1 94  ? -52.21240 -14.66028 83.48911  1.000 58.66603  ? 91  TYR A CZ  1 
ATOM   722  O OH  . TYR A 1 94  ? -51.26113 -14.15466 84.35072  1.000 64.96494  ? 91  TYR A OH  1 
ATOM   723  N N   . TYR A 1 95  ? -58.48996 -15.40080 80.28411  1.000 54.78045  ? 92  TYR A N   1 
ATOM   724  C CA  . TYR A 1 95  ? -59.65724 -15.39474 79.42035  1.000 52.84381  ? 92  TYR A CA  1 
ATOM   725  C C   . TYR A 1 95  ? -59.37878 -14.63629 78.13045  1.000 52.52165  ? 92  TYR A C   1 
ATOM   726  O O   . TYR A 1 95  ? -58.61325 -13.66910 78.09987  1.000 52.98186  ? 92  TYR A O   1 
ATOM   727  C CB  . TYR A 1 95  ? -60.86138 -14.75268 80.11668  1.000 45.60662  ? 92  TYR A CB  1 
ATOM   728  C CG  . TYR A 1 95  ? -61.62138 -15.63816 81.07928  1.000 48.27089  ? 92  TYR A CG  1 
ATOM   729  C CD1 . TYR A 1 95  ? -62.63092 -16.47439 80.62632  1.000 57.26658  ? 92  TYR A CD1 1 
ATOM   730  C CD2 . TYR A 1 95  ? -61.36979 -15.59633 82.44749  1.000 55.43424  ? 92  TYR A CD2 1 
ATOM   731  C CE1 . TYR A 1 95  ? -63.34693 -17.27190 81.50096  1.000 65.88623  ? 92  TYR A CE1 1 
ATOM   732  C CE2 . TYR A 1 95  ? -62.08297 -16.38825 83.33155  1.000 64.49722  ? 92  TYR A CE2 1 
ATOM   733  C CZ  . TYR A 1 95  ? -63.07030 -17.22412 82.85134  1.000 71.97788  ? 92  TYR A CZ  1 
ATOM   734  O OH  . TYR A 1 95  ? -63.78384 -18.01551 83.72300  1.000 81.18493  ? 92  TYR A OH  1 
ATOM   735  N N   . CYS A 1 96  ? -60.03920 -15.08527 77.07291  1.000 53.71465  ? 93  CYS A N   1 
ATOM   736  C CA  . CYS A 1 96  ? -60.05511 -14.42851 75.77574  1.000 52.86763  ? 93  CYS A CA  1 
ATOM   737  C C   . CYS A 1 96  ? -61.41795 -13.78021 75.57422  1.000 52.88322  ? 93  CYS A C   1 
ATOM   738  O O   . CYS A 1 96  ? -62.45030 -14.42061 75.80256  1.000 58.21980  ? 93  CYS A O   1 
ATOM   739  C CB  . CYS A 1 96  ? -59.77280 -15.44008 74.66504  1.000 65.06191  ? 93  CYS A CB  1 
ATOM   740  S SG  . CYS A 1 96  ? -59.33427 -14.75421 73.07507  1.000 95.35057  ? 93  CYS A SG  1 
ATOM   741  N N   . ALA A 1 97  ? -61.42133 -12.51966 75.13911  1.000 44.65430  ? 94  ALA A N   1 
ATOM   742  C CA  . ALA A 1 97  ? -62.65509 -11.76301 74.97718  1.000 51.77663  ? 94  ALA A CA  1 
ATOM   743  C C   . ALA A 1 97  ? -62.59882 -10.91805 73.71374  1.000 58.15090  ? 94  ALA A C   1 
ATOM   744  O O   . ALA A 1 97  ? -61.52556 -10.52672 73.24690  1.000 62.66889  ? 94  ALA A O   1 
ATOM   745  C CB  . ALA A 1 97  ? -62.93049 -10.85477 76.18002  1.000 62.41572  ? 94  ALA A CB  1 
ATOM   746  N N   . GLY A 1 98  ? -63.78734 -10.61148 73.18618  1.000 63.34272  ? 95  GLY A N   1 
ATOM   747  C CA  . GLY A 1 98  ? -63.90403 -9.81483  71.98660  1.000 64.96385  ? 95  GLY A CA  1 
ATOM   748  C C   . GLY A 1 98  ? -64.91672 -8.69639  72.14691  1.000 72.33278  ? 95  GLY A C   1 
ATOM   749  O O   . GLY A 1 98  ? -65.76802 -8.71189  73.03816  1.000 76.70428  ? 95  GLY A O   1 
ATOM   750  N N   . SER A 1 99  ? -64.80772 -7.71472  71.24623  1.000 75.11768  ? 96  SER A N   1 
ATOM   751  C CA  . SER A 1 99  ? -65.64737 -6.52115  71.21206  1.000 81.04322  ? 96  SER A CA  1 
ATOM   752  C C   . SER A 1 99  ? -66.04417 -6.20175  69.77382  1.000 87.42661  ? 96  SER A C   1 
ATOM   753  O O   . SER A 1 99  ? -65.20435 -6.27214  68.86163  1.000 87.96445  ? 96  SER A O   1 
ATOM   754  C CB  . SER A 1 99  ? -64.92624 -5.32401  71.84945  1.000 81.94205  ? 96  SER A CB  1 
ATOM   755  O OG  . SER A 1 99  ? -63.58195 -5.23277  71.41075  1.000 86.17846  ? 96  SER A OG  1 
ATOM   756  N N   . PRO A 1 100 ? -67.30944 -5.83599  69.54304  1.000 87.90057  ? 97  PRO A N   1 
ATOM   757  C CA  . PRO A 1 100 ? -67.86175 -5.89278  68.18128  1.000 81.61498  ? 97  PRO A CA  1 
ATOM   758  C C   . PRO A 1 100 ? -67.50255 -4.72186  67.27587  1.000 87.28640  ? 97  PRO A C   1 
ATOM   759  O O   . PRO A 1 100 ? -67.78243 -4.79892  66.07199  1.000 93.88081  ? 97  PRO A O   1 
ATOM   760  C CB  . PRO A 1 100 ? -69.37588 -5.95001  68.43522  1.000 82.80897  ? 97  PRO A CB  1 
ATOM   761  C CG  . PRO A 1 100 ? -69.54925 -5.18232  69.70201  1.000 98.81848  ? 97  PRO A CG  1 
ATOM   762  C CD  . PRO A 1 100 ? -68.34375 -5.51795  70.54477  1.000 95.20888  ? 97  PRO A CD  1 
ATOM   763  N N   . SER A 1 101 ? -66.87644 -3.66199  67.77968  1.000 87.97694  ? 98  SER A N   1 
ATOM   764  C CA  . SER A 1 101 ? -66.61120 -2.49750  66.94313  1.000 83.15605  ? 98  SER A CA  1 
ATOM   765  C C   . SER A 1 101 ? -65.40312 -2.73356  66.04187  1.000 78.20728  ? 98  SER A C   1 
ATOM   766  O O   . SER A 1 101 ? -64.35988 -3.21725  66.49255  1.000 78.69933  ? 98  SER A O   1 
ATOM   767  C CB  . SER A 1 101 ? -66.39528 -1.25317  67.79844  1.000 82.70087  ? 98  SER A CB  1 
ATOM   768  O OG  . SER A 1 101 ? -66.03644 -0.15728  66.97615  1.000 93.37040  ? 98  SER A OG  1 
ATOM   769  N N   . GLY A 1 102 ? -65.54526 -2.37754  64.76480  1.000 72.30533  ? 99  GLY A N   1 
ATOM   770  C CA  . GLY A 1 102 ? -64.48207 -2.50629  63.79609  1.000 84.57171  ? 99  GLY A CA  1 
ATOM   771  C C   . GLY A 1 102 ? -64.16000 -1.17379  63.14272  1.000 88.44370  ? 99  GLY A C   1 
ATOM   772  O O   . GLY A 1 102 ? -64.83441 -0.16569  63.36310  1.000 90.11822  ? 99  GLY A O   1 
ATOM   773  N N   . HIS A 1 103 ? -63.09941 -1.19005  62.33469  1.000 87.04063  ? 100 HIS A N   1 
ATOM   774  C CA  . HIS A 1 103 ? -62.61457 0.00464   61.64267  1.000 87.86543  ? 100 HIS A CA  1 
ATOM   775  C C   . HIS A 1 103 ? -62.29399 1.14903   62.60646  1.000 87.93049  ? 100 HIS A C   1 
ATOM   776  O O   . HIS A 1 103 ? -62.11803 2.29466   62.17775  1.000 89.02979  ? 100 HIS A O   1 
ATOM   777  C CB  . HIS A 1 103 ? -63.61351 0.47105   60.57483  1.000 94.67518  ? 100 HIS A CB  1 
ATOM   778  C CG  . HIS A 1 103 ? -63.40245 -0.15846  59.23386  1.000 95.42021  ? 100 HIS A CG  1 
ATOM   779  N ND1 . HIS A 1 103 ? -63.17915 -1.50923  59.07202  1.000 88.51238  ? 100 HIS A ND1 1 
ATOM   780  C CD2 . HIS A 1 103 ? -63.36475 0.38204   57.99256  1.000 96.36619  ? 100 HIS A CD2 1 
ATOM   781  C CE1 . HIS A 1 103 ? -63.01739 -1.77468  57.78828  1.000 99.68240  ? 100 HIS A CE1 1 
ATOM   782  N NE2 . HIS A 1 103 ? -63.12972 -0.64514  57.11175  1.000 100.31999 ? 100 HIS A NE2 1 
ATOM   783  N N   . TYR A 1 104 A -62.21721 0.86289   63.90748  1.000 80.52235  ? 100 TYR A N   1 
ATOM   784  C CA  . TYR A 1 104 A -61.89893 1.85541   64.92374  1.000 78.04656  ? 100 TYR A CA  1 
ATOM   785  C C   . TYR A 1 104 A -60.73584 1.35413   65.76606  1.000 72.90966  ? 100 TYR A C   1 
ATOM   786  O O   . TYR A 1 104 A -60.52881 0.14736   65.90845  1.000 75.17308  ? 100 TYR A O   1 
ATOM   787  C CB  . TYR A 1 104 A -63.11743 2.17570   65.81847  1.000 71.05094  ? 100 TYR A CB  1 
ATOM   788  C CG  . TYR A 1 104 A -64.22676 2.90349   65.08403  1.000 80.02437  ? 100 TYR A CG  1 
ATOM   789  C CD1 . TYR A 1 104 A -64.01297 4.16860   64.56925  1.000 83.54597  ? 100 TYR A CD1 1 
ATOM   790  C CD2 . TYR A 1 104 A -65.48688 2.34187   64.92302  1.000 85.59708  ? 100 TYR A CD2 1 
ATOM   791  C CE1 . TYR A 1 104 A -65.00221 4.85555   63.89346  1.000 81.35165  ? 100 TYR A CE1 1 
ATOM   792  C CE2 . TYR A 1 104 A -66.49457 3.02644   64.24564  1.000 88.35900  ? 100 TYR A CE2 1 
ATOM   793  C CZ  . TYR A 1 104 A -66.23934 4.28664   63.73515  1.000 79.94879  ? 100 TYR A CZ  1 
ATOM   794  O OH  . TYR A 1 104 A -67.20991 4.99177   63.06085  1.000 81.46822  ? 100 TYR A OH  1 
ATOM   795  N N   . SER A 1 105 B -59.97120 2.29307   66.32203  1.000 67.29099  ? 100 SER A N   1 
ATOM   796  C CA  . SER A 1 105 B -58.71494 1.95433   66.97899  1.000 71.65104  ? 100 SER A CA  1 
ATOM   797  C C   . SER A 1 105 B -58.51856 2.58291   68.35081  1.000 81.63998  ? 100 SER A C   1 
ATOM   798  O O   . SER A 1 105 B -57.67581 2.08922   69.11130  1.000 84.60757  ? 100 SER A O   1 
ATOM   799  C CB  . SER A 1 105 B -57.53265 2.34149   66.08219  1.000 78.05329  ? 100 SER A CB  1 
ATOM   800  O OG  . SER A 1 105 B -57.73935 3.62901   65.53201  1.000 83.20781  ? 100 SER A OG  1 
ATOM   801  N N   . TRP A 1 106 C -59.24200 3.64476   68.69553  1.000 82.45371  ? 100 TRP A N   1 
ATOM   802  C CA  . TRP A 1 106 C -59.18570 4.16232   70.05630  1.000 69.87946  ? 100 TRP A CA  1 
ATOM   803  C C   . TRP A 1 106 C -59.84981 3.17960   71.00621  1.000 66.07439  ? 100 TRP A C   1 
ATOM   804  O O   . TRP A 1 106 C -60.88818 2.59510   70.69121  1.000 71.76562  ? 100 TRP A O   1 
ATOM   805  C CB  . TRP A 1 106 C -59.88209 5.51719   70.15341  1.000 72.50943  ? 100 TRP A CB  1 
ATOM   806  C CG  . TRP A 1 106 C -59.82213 6.13404   71.52449  1.000 71.63278  ? 100 TRP A CG  1 
ATOM   807  C CD1 . TRP A 1 106 C -58.71848 6.27491   72.31131  1.000 74.16954  ? 100 TRP A CD1 1 
ATOM   808  C CD2 . TRP A 1 106 C -60.91259 6.70457   72.25983  1.000 75.39255  ? 100 TRP A CD2 1 
ATOM   809  N NE1 . TRP A 1 106 C -59.05117 6.89748   73.49062  1.000 71.12011  ? 100 TRP A NE1 1 
ATOM   810  C CE2 . TRP A 1 106 C -60.39331 7.17014   73.48389  1.000 70.85042  ? 100 TRP A CE2 1 
ATOM   811  C CE3 . TRP A 1 106 C -62.27775 6.86640   72.00162  1.000 80.97966  ? 100 TRP A CE3 1 
ATOM   812  C CZ2 . TRP A 1 106 C -61.19032 7.78534   74.44779  1.000 70.74232  ? 100 TRP A CZ2 1 
ATOM   813  C CZ3 . TRP A 1 106 C -63.06735 7.47732   72.95959  1.000 78.47846  ? 100 TRP A CZ3 1 
ATOM   814  C CH2 . TRP A 1 106 C -62.52203 7.92891   74.16750  1.000 69.91669  ? 100 TRP A CH2 1 
ATOM   815  N N   . LEU A 1 107 D -59.25348 3.00676   72.18238  1.000 67.82316  ? 100 LEU A N   1 
ATOM   816  C CA  . LEU A 1 107 D -59.77111 2.01793   73.11627  1.000 71.58345  ? 100 LEU A CA  1 
ATOM   817  C C   . LEU A 1 107 D -61.16644 2.35717   73.61602  1.000 60.43962  ? 100 LEU A C   1 
ATOM   818  O O   . LEU A 1 107 D -61.87444 1.46139   74.08875  1.000 54.43556  ? 100 LEU A O   1 
ATOM   819  C CB  . LEU A 1 107 D -58.81301 1.85419   74.29261  1.000 78.41600  ? 100 LEU A CB  1 
ATOM   820  C CG  . LEU A 1 107 D -57.82682 0.69799   74.15750  1.000 74.82333  ? 100 LEU A CG  1 
ATOM   821  C CD1 . LEU A 1 107 D -56.90903 0.89454   72.96200  1.000 59.61017  ? 100 LEU A CD1 1 
ATOM   822  C CD2 . LEU A 1 107 D -57.03207 0.56015   75.43629  1.000 70.95964  ? 100 LEU A CD2 1 
ATOM   823  N N   . GLY A 1 108 E -61.58175 3.62059   73.52089  1.000 62.08516  ? 100 GLY A N   1 
ATOM   824  C CA  . GLY A 1 108 E -62.91136 3.98622   73.97022  1.000 68.03733  ? 100 GLY A CA  1 
ATOM   825  C C   . GLY A 1 108 E -64.02870 3.50434   73.06323  1.000 61.71797  ? 100 GLY A C   1 
ATOM   826  O O   . GLY A 1 108 E -65.18306 3.41487   73.50322  1.000 57.93055  ? 100 GLY A O   1 
ATOM   827  N N   . TYR A 1 109 F -63.71625 3.19935   71.80709  1.000 59.26013  ? 100 TYR A N   1 
ATOM   828  C CA  . TYR A 1 109 F -64.71649 2.74114   70.85703  1.000 57.05225  ? 100 TYR A CA  1 
ATOM   829  C C   . TYR A 1 109 F -64.93507 1.23478   70.91084  1.000 61.75069  ? 100 TYR A C   1 
ATOM   830  O O   . TYR A 1 109 F -65.79105 0.71846   70.18622  1.000 66.45672  ? 100 TYR A O   1 
ATOM   831  C CB  . TYR A 1 109 F -64.34073 3.16875   69.43043  1.000 65.15443  ? 100 TYR A CB  1 
ATOM   832  C CG  . TYR A 1 109 F -64.52229 4.65250   69.16194  1.000 73.82714  ? 100 TYR A CG  1 
ATOM   833  C CD1 . TYR A 1 109 F -65.78089 5.24544   69.23032  1.000 84.38908  ? 100 TYR A CD1 1 
ATOM   834  C CD2 . TYR A 1 109 F -63.43928 5.45660   68.82596  1.000 68.36866  ? 100 TYR A CD2 1 
ATOM   835  C CE1 . TYR A 1 109 F -65.95139 6.60262   68.98271  1.000 89.25870  ? 100 TYR A CE1 1 
ATOM   836  C CE2 . TYR A 1 109 F -63.60006 6.81150   68.57585  1.000 71.84156  ? 100 TYR A CE2 1 
ATOM   837  C CZ  . TYR A 1 109 F -64.85437 7.37944   68.65488  1.000 82.73713  ? 100 TYR A CZ  1 
ATOM   838  O OH  . TYR A 1 109 F -65.00334 8.72609   68.40521  1.000 82.94308  ? 100 TYR A OH  1 
ATOM   839  N N   . PHE A 1 110 G -64.19851 0.51682   71.74902  1.000 68.20065  ? 100 PHE A N   1 
ATOM   840  C CA  . PHE A 1 110 G -64.47787 -0.89720  71.97513  1.000 74.42497  ? 100 PHE A CA  1 
ATOM   841  C C   . PHE A 1 110 G -64.15832 -1.24869  73.42744  1.000 73.36233  ? 100 PHE A C   1 
ATOM   842  O O   . PHE A 1 110 G -63.41547 -2.18627  73.72028  1.000 69.17110  ? 100 PHE A O   1 
ATOM   843  C CB  . PHE A 1 110 G -63.70841 -1.78404  70.99292  1.000 76.70094  ? 100 PHE A CB  1 
ATOM   844  C CG  . PHE A 1 110 G -62.30070 -1.32123  70.69930  1.000 66.40969  ? 100 PHE A CG  1 
ATOM   845  C CD1 . PHE A 1 110 G -61.31724 -1.38737  71.66858  1.000 67.34879  ? 100 PHE A CD1 1 
ATOM   846  C CD2 . PHE A 1 110 G -61.95306 -0.86226  69.43932  1.000 68.00014  ? 100 PHE A CD2 1 
ATOM   847  C CE1 . PHE A 1 110 G -60.02879 -0.97927  71.39777  1.000 63.60065  ? 100 PHE A CE1 1 
ATOM   848  C CE2 . PHE A 1 110 G -60.65905 -0.45165  69.16571  1.000 68.96042  ? 100 PHE A CE2 1 
ATOM   849  C CZ  . PHE A 1 110 G -59.69983 -0.51026  70.14620  1.000 63.05056  ? 100 PHE A CZ  1 
ATOM   850  N N   . TYR A 1 111 H -64.73022 -0.49803  74.36306  1.000 74.05312  ? 100 TYR A N   1 
ATOM   851  C CA  . TYR A 1 111 H -64.38436 -0.66276  75.76638  1.000 66.45140  ? 100 TYR A CA  1 
ATOM   852  C C   . TYR A 1 111 H -65.18774 -1.74833  76.46735  1.000 60.23885  ? 100 TYR A C   1 
ATOM   853  O O   . TYR A 1 111 H -64.82615 -2.13785  77.58234  1.000 51.47738  ? 100 TYR A O   1 
ATOM   854  C CB  . TYR A 1 111 H -64.55656 0.66662   76.50637  1.000 70.97934  ? 100 TYR A CB  1 
ATOM   855  C CG  . TYR A 1 111 H -65.97253 0.95561   76.94383  1.000 75.78566  ? 100 TYR A CG  1 
ATOM   856  C CD1 . TYR A 1 111 H -66.94175 1.33407   76.01659  1.000 76.11491  ? 100 TYR A CD1 1 
ATOM   857  C CD2 . TYR A 1 111 H -66.33938 0.86161   78.28190  1.000 71.02953  ? 100 TYR A CD2 1 
ATOM   858  C CE1 . TYR A 1 111 H -68.23096 1.60638   76.40692  1.000 75.55221  ? 100 TYR A CE1 1 
ATOM   859  C CE2 . TYR A 1 111 H -67.62633 1.12827   78.68089  1.000 65.91907  ? 100 TYR A CE2 1 
ATOM   860  C CZ  . TYR A 1 111 H -68.56487 1.50193   77.73892  1.000 73.86899  ? 100 TYR A CZ  1 
ATOM   861  O OH  . TYR A 1 111 H -69.84671 1.77190   78.13161  1.000 83.79331  ? 100 TYR A OH  1 
ATOM   862  N N   . ALA A 1 112 I -66.25265 -2.24507  75.85398  1.000 61.16084  ? 100 ALA A N   1 
ATOM   863  C CA  . ALA A 1 112 I -67.05196 -3.31009  76.43616  1.000 65.93328  ? 100 ALA A CA  1 
ATOM   864  C C   . ALA A 1 112 I -66.66599 -4.65424  75.82610  1.000 69.67410  ? 100 ALA A C   1 
ATOM   865  O O   . ALA A 1 112 I -66.03711 -4.72461  74.76910  1.000 72.67544  ? 100 ALA A O   1 
ATOM   866  C CB  . ALA A 1 112 I -68.54373 -3.03637  76.23143  1.000 69.59915  ? 100 ALA A CB  1 
ATOM   867  N N   . MET A 1 113 J -67.04576 -5.73000  76.51325  1.000 68.54351  ? 100 MET A N   1 
ATOM   868  C CA  . MET A 1 113 J -66.72857 -7.08974  76.08892  1.000 70.10435  ? 100 MET A CA  1 
ATOM   869  C C   . MET A 1 113 J -68.00589 -7.91977  76.10813  1.000 82.91539  ? 100 MET A C   1 
ATOM   870  O O   . MET A 1 113 J -68.72613 -7.92274  77.11046  1.000 92.44374  ? 100 MET A O   1 
ATOM   871  C CB  . MET A 1 113 J -65.66421 -7.71730  77.00651  1.000 64.33300  ? 100 MET A CB  1 
ATOM   872  C CG  . MET A 1 113 J -64.22428 -7.26566  76.74001  1.000 61.40370  ? 100 MET A CG  1 
ATOM   873  S SD  . MET A 1 113 J -63.19678 -7.22252  78.22924  1.000 52.53933  ? 100 MET A SD  1 
ATOM   874  C CE  . MET A 1 113 J -63.80244 -5.72309  79.00428  1.000 69.89845  ? 100 MET A CE  1 
ATOM   875  N N   . ASP A 1 114 ? -68.29546 -8.62314  75.00806  1.000 78.00441  ? 101 ASP A N   1 
ATOM   876  C CA  . ASP A 1 114 ? -69.50874 -9.42899  74.93621  1.000 81.23674  ? 101 ASP A CA  1 
ATOM   877  C C   . ASP A 1 114 ? -69.28936 -10.89219 74.57313  1.000 80.56639  ? 101 ASP A C   1 
ATOM   878  O O   . ASP A 1 114 ? -70.19778 -11.69961 74.79917  1.000 93.64722  ? 101 ASP A O   1 
ATOM   879  C CB  . ASP A 1 114 ? -70.51050 -8.82209  73.93711  1.000 90.99041  ? 101 ASP A CB  1 
ATOM   880  C CG  . ASP A 1 114 ? -69.87923 -8.49088  72.60217  1.000 97.21855  ? 101 ASP A CG  1 
ATOM   881  O OD1 . ASP A 1 114 ? -68.63593 -8.38864  72.54959  1.000 95.18578  ? 101 ASP A OD1 1 
ATOM   882  O OD2 . ASP A 1 114 ? -70.62675 -8.32362  71.61167  1.000 104.77801 ? 101 ASP A OD2 1 
ATOM   883  N N   . VAL A 1 115 ? -68.13465 -11.26192 74.02533  1.000 67.24695  ? 102 VAL A N   1 
ATOM   884  C CA  . VAL A 1 115 ? -67.84490 -12.64340 73.65633  1.000 66.55433  ? 102 VAL A CA  1 
ATOM   885  C C   . VAL A 1 115 ? -66.63581 -13.10669 74.45511  1.000 68.96116  ? 102 VAL A C   1 
ATOM   886  O O   . VAL A 1 115 ? -65.61584 -12.41256 74.49880  1.000 67.01768  ? 102 VAL A O   1 
ATOM   887  C CB  . VAL A 1 115 ? -67.59701 -12.78537 72.14455  1.000 61.58638  ? 102 VAL A CB  1 
ATOM   888  C CG1 . VAL A 1 115 ? -67.61084 -14.24958 71.73943  1.000 79.76534  ? 102 VAL A CG1 1 
ATOM   889  C CG2 . VAL A 1 115 ? -68.64412 -12.00799 71.37072  1.000 76.56042  ? 102 VAL A CG2 1 
ATOM   890  N N   . TRP A 1 116 ? -66.74681 -14.27529 75.08264  1.000 68.93643  ? 103 TRP A N   1 
ATOM   891  C CA  . TRP A 1 116 ? -65.72888 -14.75881 76.00586  1.000 54.69701  ? 103 TRP A CA  1 
ATOM   892  C C   . TRP A 1 116 ? -65.38996 -16.21005 75.68694  1.000 59.65961  ? 103 TRP A C   1 
ATOM   893  O O   . TRP A 1 116 ? -65.90622 -16.79634 74.73210  1.000 73.82298  ? 103 TRP A O   1 
ATOM   894  C CB  . TRP A 1 116 ? -66.20048 -14.61076 77.45543  1.000 55.08810  ? 103 TRP A CB  1 
ATOM   895  C CG  . TRP A 1 116 ? -66.24960 -13.18820 77.89988  1.000 54.98199  ? 103 TRP A CG  1 
ATOM   896  C CD1 . TRP A 1 116 ? -67.17303 -12.25170 77.54266  1.000 62.37637  ? 103 TRP A CD1 1 
ATOM   897  C CD2 . TRP A 1 116 ? -65.33526 -12.53181 78.78258  1.000 56.82474  ? 103 TRP A CD2 1 
ATOM   898  N NE1 . TRP A 1 116 ? -66.89014 -11.05229 78.14585  1.000 64.26815  ? 103 TRP A NE1 1 
ATOM   899  C CE2 . TRP A 1 116 ? -65.76645 -11.19820 78.91409  1.000 57.37815  ? 103 TRP A CE2 1 
ATOM   900  C CE3 . TRP A 1 116 ? -64.19424 -12.94232 79.47569  1.000 66.49837  ? 103 TRP A CE3 1 
ATOM   901  C CZ2 . TRP A 1 116 ? -65.09767 -10.27398 79.70844  1.000 61.26342  ? 103 TRP A CZ2 1 
ATOM   902  C CZ3 . TRP A 1 116 ? -63.53164 -12.02423 80.26397  1.000 59.39284  ? 103 TRP A CZ3 1 
ATOM   903  C CH2 . TRP A 1 116 ? -63.98418 -10.70536 80.37431  1.000 59.55746  ? 103 TRP A CH2 1 
ATOM   904  N N   . GLY A 1 117 ? -64.51515 -16.79759 76.50783  1.000 52.47667  ? 104 GLY A N   1 
ATOM   905  C CA  . GLY A 1 117 ? -64.06254 -18.15773 76.29940  1.000 63.01852  ? 104 GLY A CA  1 
ATOM   906  C C   . GLY A 1 117 ? -63.99009 -18.93133 77.60334  1.000 72.26873  ? 104 GLY A C   1 
ATOM   907  O O   . GLY A 1 117 ? -64.30568 -18.40758 78.67280  1.000 75.51675  ? 104 GLY A O   1 
ATOM   908  N N   . GLN A 1 118 ? -63.55559 -20.19479 77.49194  1.000 80.09961  ? 105 GLN A N   1 
ATOM   909  C CA  . GLN A 1 118 ? -63.50577 -21.08541 78.65281  1.000 79.09326  ? 105 GLN A CA  1 
ATOM   910  C C   . GLN A 1 118 ? -62.43314 -20.65306 79.64462  1.000 70.10703  ? 105 GLN A C   1 
ATOM   911  O O   . GLN A 1 118 ? -62.68442 -20.57616 80.85415  1.000 65.47843  ? 105 GLN A O   1 
ATOM   912  C CB  . GLN A 1 118 ? -63.26546 -22.53061 78.20746  1.000 74.99395  ? 105 GLN A CB  1 
ATOM   913  C CG  . GLN A 1 118 ? -64.22372 -23.03225 77.13563  1.000 91.62917  ? 105 GLN A CG  1 
ATOM   914  C CD  . GLN A 1 118 ? -65.68195 -22.89536 77.54442  1.000 109.71249 ? 105 GLN A CD  1 
ATOM   915  O OE1 . GLN A 1 118 ? -66.05104 -23.21010 78.67566  1.000 104.86431 ? 105 GLN A OE1 1 
ATOM   916  N NE2 . GLN A 1 118 ? -66.51736 -22.42255 76.62303  1.000 118.58095 ? 105 GLN A NE2 1 
ATOM   917  N N   . GLY A 1 119 ? -61.22953 -20.37905 79.15473  1.000 63.89893  ? 106 GLY A N   1 
ATOM   918  C CA  . GLY A 1 119 ? -60.13800 -19.98893 80.02379  1.000 68.51510  ? 106 GLY A CA  1 
ATOM   919  C C   . GLY A 1 119 ? -59.12841 -21.09903 80.20847  1.000 76.64236  ? 106 GLY A C   1 
ATOM   920  O O   . GLY A 1 119 ? -59.49437 -22.27214 80.32506  1.000 92.47890  ? 106 GLY A O   1 
ATOM   921  N N   . THR A 1 120 ? -57.84846 -20.74308 80.23406  1.000 65.42147  ? 107 THR A N   1 
ATOM   922  C CA  . THR A 1 120 ? -56.76767 -21.69905 80.43107  1.000 70.62627  ? 107 THR A CA  1 
ATOM   923  C C   . THR A 1 120 ? -55.98204 -21.32265 81.67639  1.000 65.37307  ? 107 THR A C   1 
ATOM   924  O O   . THR A 1 120 ? -55.81793 -20.13684 81.98154  1.000 60.22301  ? 107 THR A O   1 
ATOM   925  C CB  . THR A 1 120 ? -55.83720 -21.73363 79.22568  1.000 66.64559  ? 107 THR A CB  1 
ATOM   926  O OG1 . THR A 1 120 ? -55.54243 -20.39059 78.82716  1.000 56.04757  ? 107 THR A OG1 1 
ATOM   927  C CG2 . THR A 1 120 ? -56.48800 -22.48104 78.06257  1.000 69.03300  ? 107 THR A CG2 1 
ATOM   928  N N   . VAL A 1 121 ? -55.48904 -22.32711 82.38214  1.000 69.40502  ? 108 VAL A N   1 
ATOM   929  C CA  . VAL A 1 121 ? -54.83634 -22.11669 83.66833  1.000 67.09524  ? 108 VAL A CA  1 
ATOM   930  C C   . VAL A 1 121 ? -53.33581 -22.01636 83.47279  1.000 65.84083  ? 108 VAL A C   1 
ATOM   931  O O   . VAL A 1 121 ? -52.74114 -22.74205 82.66387  1.000 62.19491  ? 108 VAL A O   1 
ATOM   932  C CB  . VAL A 1 121 ? -55.18793 -23.24526 84.65171  1.000 62.22855  ? 108 VAL A CB  1 
ATOM   933  C CG1 . VAL A 1 121 ? -54.85132 -22.83475 86.08295  1.000 41.16589  ? 108 VAL A CG1 1 
ATOM   934  C CG2 . VAL A 1 121 ? -56.64128 -23.57800 84.51990  1.000 61.73582  ? 108 VAL A CG2 1 
ATOM   935  N N   . THR A 1 122 ? -52.72651 -21.10418 84.22528  1.000 62.25455  ? 109 THR A N   1 
ATOM   936  C CA  . THR A 1 122 ? -51.27728 -20.94292 84.27095  1.000 66.24352  ? 109 THR A CA  1 
ATOM   937  C C   . THR A 1 122 ? -50.86654 -20.86006 85.73335  1.000 73.21768  ? 109 THR A C   1 
ATOM   938  O O   . THR A 1 122 ? -51.17971 -19.87775 86.41288  1.000 71.05428  ? 109 THR A O   1 
ATOM   939  C CB  . THR A 1 122 ? -50.84249 -19.69735 83.50535  1.000 49.12276  ? 109 THR A CB  1 
ATOM   940  O OG1 . THR A 1 122 ? -51.60872 -18.57670 83.95132  1.000 47.46746  ? 109 THR A OG1 1 
ATOM   941  C CG2 . THR A 1 122 ? -51.07793 -19.88874 82.02611  1.000 55.20438  ? 109 THR A CG2 1 
ATOM   942  N N   . VAL A 1 123 ? -50.18639 -21.88986 86.22038  1.000 65.42129  ? 110 VAL A N   1 
ATOM   943  C CA  . VAL A 1 123 ? -49.89926 -22.02717 87.63858  1.000 60.09081  ? 110 VAL A CA  1 
ATOM   944  C C   . VAL A 1 123 ? -48.39406 -22.13282 87.84677  1.000 67.71657  ? 110 VAL A C   1 
ATOM   945  O O   . VAL A 1 123 ? -47.68296 -22.73490 87.03453  1.000 75.84818  ? 110 VAL A O   1 
ATOM   946  C CB  . VAL A 1 123 ? -50.64399 -23.24637 88.22070  1.000 72.94152  ? 110 VAL A CB  1 
ATOM   947  C CG1 . VAL A 1 123 ? -50.08694 -23.64837 89.57566  1.000 99.97573  ? 110 VAL A CG1 1 
ATOM   948  C CG2 . VAL A 1 123 ? -52.12317 -22.93263 88.33033  1.000 68.94560  ? 110 VAL A CG2 1 
ATOM   949  N N   . SER A 1 124 ? -47.91475 -21.54196 88.94369  1.000 71.69302  ? 111 SER A N   1 
ATOM   950  C CA  . SER A 1 124 ? -46.48964 -21.45539 89.25658  1.000 74.25752  ? 111 SER A CA  1 
ATOM   951  C C   . SER A 1 124 ? -46.30771 -21.63916 90.75744  1.000 85.66927  ? 111 SER A C   1 
ATOM   952  O O   . SER A 1 124 ? -46.70170 -20.76789 91.54040  1.000 95.14068  ? 111 SER A O   1 
ATOM   953  C CB  . SER A 1 124 ? -45.92828 -20.10998 88.80911  1.000 69.51504  ? 111 SER A CB  1 
ATOM   954  O OG  . SER A 1 124 ? -46.53102 -19.71216 87.58979  1.000 62.75356  ? 111 SER A OG  1 
ATOM   955  N N   . SER A 1 125 ? -45.70153 -22.75198 91.16092  1.000 82.86769  ? 112 SER A N   1 
ATOM   956  C CA  . SER A 1 125 ? -45.47484 -23.04984 92.56826  1.000 107.14549 ? 112 SER A CA  1 
ATOM   957  C C   . SER A 1 125 ? -43.97930 -23.10823 92.85392  1.000 104.81080 ? 112 SER A C   1 
ATOM   958  O O   . SER A 1 125 ? -43.14801 -23.14178 91.94365  1.000 85.41790  ? 112 SER A O   1 
ATOM   959  C CB  . SER A 1 125 ? -46.15299 -24.36594 92.97776  1.000 109.43692 ? 112 SER A CB  1 
ATOM   960  O OG  . SER A 1 125 ? -47.55996 -24.21661 93.07548  1.000 104.51831 ? 112 SER A OG  1 
ATOM   961  N N   . GLY A 1 126 ? -43.64475 -23.11106 94.14158  1.000 104.36172 ? 113 GLY A N   1 
ATOM   962  C CA  . GLY A 1 126 ? -42.25913 -23.14336 94.57338  1.000 99.55280  ? 113 GLY A CA  1 
ATOM   963  C C   . GLY A 1 126 ? -41.76296 -24.53746 94.90373  1.000 97.29616  ? 113 GLY A C   1 
ATOM   964  O O   . GLY A 1 126 ? -40.91672 -25.08851 94.20018  1.000 101.06992 ? 113 GLY A O   1 
ATOM   965  N N   . GLN A 1 141 ? -55.52835 -4.72891  93.41916  1.000 132.05460 ? 128 GLN A N   1 
ATOM   966  C CA  . GLN A 1 141 ? -55.91056 -5.38710  92.17165  1.000 134.68806 ? 128 GLN A CA  1 
ATOM   967  C C   . GLN A 1 141 ? -57.34793 -5.05483  91.75360  1.000 133.47693 ? 128 GLN A C   1 
ATOM   968  O O   . GLN A 1 141 ? -58.00358 -5.84619  91.07074  1.000 107.75909 ? 128 GLN A O   1 
ATOM   969  C CB  . GLN A 1 141 ? -55.73417 -6.90334  92.29951  1.000 135.99664 ? 128 GLN A CB  1 
ATOM   970  C CG  . GLN A 1 141 ? -56.09550 -7.46870  93.66678  1.000 150.46171 ? 128 GLN A CG  1 
ATOM   971  C CD  . GLN A 1 141 ? -55.43197 -8.80852  93.93148  1.000 148.05314 ? 128 GLN A CD  1 
ATOM   972  O OE1 . GLN A 1 141 ? -54.61668 -9.27679  93.13583  1.000 138.22917 ? 128 GLN A OE1 1 
ATOM   973  N NE2 . GLN A 1 141 ? -55.76956 -9.42654  95.05855  1.000 144.35802 ? 128 GLN A NE2 1 
ATOM   974  N N   . SER A 1 142 ? -57.82591 -3.87742  92.17642  1.000 141.40570 ? 129 SER A N   1 
ATOM   975  C CA  . SER A 1 142 ? -59.15786 -3.39619  91.79834  1.000 121.64803 ? 129 SER A CA  1 
ATOM   976  C C   . SER A 1 142 ? -59.17370 -1.88083  92.01194  1.000 94.56309  ? 129 SER A C   1 
ATOM   977  O O   . SER A 1 142 ? -59.32946 -1.41747  93.14504  1.000 92.39284  ? 129 SER A O   1 
ATOM   978  C CB  . SER A 1 142 ? -60.26018 -4.08495  92.59799  1.000 112.26388 ? 129 SER A CB  1 
ATOM   979  O OG  . SER A 1 142 ? -60.11140 -3.91333  93.99940  1.000 109.06609 ? 129 SER A OG  1 
ATOM   980  N N   . ALA A 1 143 ? -59.00829 -1.12548  90.92551  1.000 80.81043  ? 130 ALA A N   1 
ATOM   981  C CA  . ALA A 1 143 ? -59.11008 0.32324   91.01655  1.000 84.28287  ? 130 ALA A CA  1 
ATOM   982  C C   . ALA A 1 143 ? -60.55726 0.81161   91.04290  1.000 82.59546  ? 130 ALA A C   1 
ATOM   983  O O   . ALA A 1 143 ? -60.78971 1.98562   91.34989  1.000 81.60224  ? 130 ALA A O   1 
ATOM   984  C CB  . ALA A 1 143 ? -58.34289 0.97989   89.86586  1.000 86.96421  ? 130 ALA A CB  1 
ATOM   985  N N   . LEU A 1 144 ? -61.52680 -0.04785  90.73001  1.000 76.53958  ? 131 LEU A N   1 
ATOM   986  C CA  . LEU A 1 144 ? -62.93496 0.19472   91.01732  1.000 64.62696  ? 131 LEU A CA  1 
ATOM   987  C C   . LEU A 1 144 ? -63.35541 -0.60145  92.24164  1.000 70.29973  ? 131 LEU A C   1 
ATOM   988  O O   . LEU A 1 144 ? -62.68378 -1.54750  92.65649  1.000 74.50840  ? 131 LEU A O   1 
ATOM   989  C CB  . LEU A 1 144 ? -63.83854 -0.16433  89.83490  1.000 60.24271  ? 131 LEU A CB  1 
ATOM   990  C CG  . LEU A 1 144 ? -63.96508 0.84710   88.69597  1.000 71.15052  ? 131 LEU A CG  1 
ATOM   991  C CD1 . LEU A 1 144 ? -64.75056 0.26894   87.53266  1.000 64.75272  ? 131 LEU A CD1 1 
ATOM   992  C CD2 . LEU A 1 144 ? -64.61520 2.11807   89.19493  1.000 77.59867  ? 131 LEU A CD2 1 
ATOM   993  N N   . THR A 1 145 ? -64.48492 -0.20425  92.82300  1.000 76.39001  ? 132 THR A N   1 
ATOM   994  C CA  . THR A 1 145 ? -64.86958 -0.68684  94.14477  1.000 73.23164  ? 132 THR A CA  1 
ATOM   995  C C   . THR A 1 145 ? -66.36330 -0.97791  94.18124  1.000 62.79663  ? 132 THR A C   1 
ATOM   996  O O   . THR A 1 145 ? -67.17674 -0.07374  93.97274  1.000 57.48631  ? 132 THR A O   1 
ATOM   997  C CB  . THR A 1 145 ? -64.49692 0.34875   95.20642  1.000 65.47417  ? 132 THR A CB  1 
ATOM   998  O OG1 . THR A 1 145 ? -65.07614 1.61286   94.85516  1.000 62.70849  ? 132 THR A OG1 1 
ATOM   999  C CG2 . THR A 1 145 ? -62.97699 0.51126   95.28253  1.000 77.10612  ? 132 THR A CG2 1 
ATOM   1000 N N   . GLN A 1 146 ? -66.72294 -2.23460  94.46061  1.000 64.70955  ? 133 GLN A N   1 
ATOM   1001 C CA  . GLN A 1 146 ? -68.11315 -2.64783  94.60419  1.000 68.21759  ? 133 GLN A CA  1 
ATOM   1002 C C   . GLN A 1 146 ? -68.34853 -3.20792  96.00242  1.000 81.50755  ? 133 GLN A C   1 
ATOM   1003 O O   . GLN A 1 146 ? -67.38448 -3.40917  96.75402  1.000 85.35890  ? 133 GLN A O   1 
ATOM   1004 C CB  . GLN A 1 146 ? -68.47468 -3.71348  93.56915  1.000 65.62893  ? 133 GLN A CB  1 
ATOM   1005 C CG  . GLN A 1 146 ? -67.98035 -3.45347  92.18066  1.000 66.42827  ? 133 GLN A CG  1 
ATOM   1006 C CD  . GLN A 1 146 ? -68.22375 -4.64078  91.28042  1.000 69.01889  ? 133 GLN A CD  1 
ATOM   1007 O OE1 . GLN A 1 146 ? -67.68047 -4.72168  90.18209  1.000 74.66921  ? 133 GLN A OE1 1 
ATOM   1008 N NE2 . GLN A 1 146 ? -69.03970 -5.58066  91.74867  1.000 69.40925  ? 133 GLN A NE2 1 
ATOM   1009 N N   . PRO A 1 147 ? -69.61454 -3.48538  96.39523  1.000 85.90294  ? 134 PRO A N   1 
ATOM   1010 C CA  . PRO A 1 147 ? -69.82860 -4.26909  97.62526  1.000 87.08578  ? 134 PRO A CA  1 
ATOM   1011 C C   . PRO A 1 147 ? -69.48746 -5.74882  97.47266  1.000 88.95226  ? 134 PRO A C   1 
ATOM   1012 O O   . PRO A 1 147 ? -69.06918 -6.18785  96.40252  1.000 102.77850 ? 134 PRO A O   1 
ATOM   1013 C CB  . PRO A 1 147 ? -71.31419 -4.05088  97.92542  1.000 92.82029  ? 134 PRO A CB  1 
ATOM   1014 C CG  . PRO A 1 147 ? -71.92105 -3.71629  96.60537  1.000 76.52461  ? 134 PRO A CG  1 
ATOM   1015 C CD  . PRO A 1 147 ? -70.87844 -2.93258  95.86541  1.000 74.34903  ? 134 PRO A CD  1 
ATOM   1016 N N   . ALA A 1 148 ? -69.65216 -6.52800  98.53879  1.000 69.90052  ? 135 ALA A N   1 
ATOM   1017 C CA  . ALA A 1 148 ? -69.52381 -7.97478  98.44180  1.000 74.94019  ? 135 ALA A CA  1 
ATOM   1018 C C   . ALA A 1 148 ? -70.78702 -8.68222  98.89120  1.000 86.69880  ? 135 ALA A C   1 
ATOM   1019 O O   . ALA A 1 148 ? -71.31224 -9.53056  98.16305  1.000 78.73925  ? 135 ALA A O   1 
ATOM   1020 C CB  . ALA A 1 148 ? -68.32900 -8.46440  99.27171  1.000 88.56011  ? 135 ALA A CB  1 
ATOM   1021 N N   . SER A 1 149 ? -71.28458 -8.35426  100.07919 1.000 106.37481 ? 136 SER A N   1 
ATOM   1022 C CA  . SER A 1 149 ? -72.49955 -8.96062  100.60155 1.000 117.77857 ? 136 SER A CA  1 
ATOM   1023 C C   . SER A 1 149 ? -73.71367 -8.22640  100.04673 1.000 116.87290 ? 136 SER A C   1 
ATOM   1024 O O   . SER A 1 149 ? -73.86522 -7.01769  100.25724 1.000 119.47850 ? 136 SER A O   1 
ATOM   1025 C CB  . SER A 1 149 ? -72.49686 -8.91724  102.12835 1.000 114.32729 ? 136 SER A CB  1 
ATOM   1026 O OG  . SER A 1 149 ? -73.71948 -9.39865  102.65187 1.000 122.65226 ? 136 SER A OG  1 
ATOM   1027 N N   . VAL A 1 150 ? -74.57617 -8.95219  99.33741  1.000 112.98658 ? 137 VAL A N   1 
ATOM   1028 C CA  . VAL A 1 150 ? -75.84835 -8.39680  98.88909  1.000 108.78189 ? 137 VAL A CA  1 
ATOM   1029 C C   . VAL A 1 150 ? -76.94080 -9.46340  98.96473  1.000 107.54810 ? 137 VAL A C   1 
ATOM   1030 O O   . VAL A 1 150 ? -77.13175 -10.26478 98.04118  1.000 93.41879  ? 137 VAL A O   1 
ATOM   1031 C CB  . VAL A 1 150 ? -75.71496 -7.77426  97.48388  1.000 86.78899  ? 137 VAL A CB  1 
ATOM   1032 C CG1 . VAL A 1 150 ? -75.17732 -8.77072  96.47919  1.000 84.51949  ? 137 VAL A CG1 1 
ATOM   1033 C CG2 . VAL A 1 150 ? -77.04844 -7.21125  97.03124  1.000 93.38855  ? 137 VAL A CG2 1 
ATOM   1034 N N   . SER A 1 151 ? -77.65380 -9.48827  100.08786 1.000 111.50553 ? 138 SER A N   1 
ATOM   1035 C CA  . SER A 1 151 ? -78.73588 -10.44211 100.27983 1.000 107.36667 ? 138 SER A CA  1 
ATOM   1036 C C   . SER A 1 151 ? -80.01081 -9.93646  99.61473  1.000 101.52485 ? 138 SER A C   1 
ATOM   1037 O O   . SER A 1 151 ? -80.32619 -8.74382  99.66690  1.000 99.48387  ? 138 SER A O   1 
ATOM   1038 C CB  . SER A 1 151 ? -78.97372 -10.67856 101.77401 1.000 105.77724 ? 138 SER A CB  1 
ATOM   1039 O OG  . SER A 1 151 ? -80.08067 -11.53561 101.99567 1.000 105.12395 ? 138 SER A OG  1 
ATOM   1040 N N   . GLY A 1 152 ? -80.73376 -10.84613 98.97033  1.000 93.97742  ? 139 GLY A N   1 
ATOM   1041 C CA  . GLY A 1 152 ? -81.98067 -10.48030 98.33066  1.000 91.49297  ? 139 GLY A CA  1 
ATOM   1042 C C   . GLY A 1 152 ? -82.98551 -11.61128 98.28053  1.000 103.96568 ? 139 GLY A C   1 
ATOM   1043 O O   . GLY A 1 152 ? -82.72712 -12.64897 97.66627  1.000 109.51591 ? 139 GLY A O   1 
ATOM   1044 N N   . SER A 1 153 ? -84.13101 -11.43115 98.93459  1.000 102.56093 ? 140 SER A N   1 
ATOM   1045 C CA  . SER A 1 153 ? -85.20116 -12.41072 98.84688  1.000 104.70716 ? 140 SER A CA  1 
ATOM   1046 C C   . SER A 1 153 ? -85.90555 -12.29261 97.49252  1.000 105.81516 ? 140 SER A C   1 
ATOM   1047 O O   . SER A 1 153 ? -85.96184 -11.20579 96.91452  1.000 106.39613 ? 140 SER A O   1 
ATOM   1048 C CB  . SER A 1 153 ? -86.19829 -12.20490 99.98504  1.000 108.66065 ? 140 SER A CB  1 
ATOM   1049 O OG  . SER A 1 153 ? -85.62393 -12.54544 101.23834 1.000 111.27038 ? 140 SER A OG  1 
ATOM   1050 N N   . PRO A 1 154 ? -86.43654 -13.39756 96.95843  1.000 110.89689 ? 141 PRO A N   1 
ATOM   1051 C CA  . PRO A 1 154 ? -87.01511 -13.36694 95.60538  1.000 109.53219 ? 141 PRO A CA  1 
ATOM   1052 C C   . PRO A 1 154 ? -88.17461 -12.38613 95.48938  1.000 114.50603 ? 141 PRO A C   1 
ATOM   1053 O O   . PRO A 1 154 ? -88.81865 -12.01886 96.47405  1.000 127.31840 ? 141 PRO A O   1 
ATOM   1054 C CB  . PRO A 1 154 ? -87.49404 -14.80886 95.38813  1.000 104.32012 ? 141 PRO A CB  1 
ATOM   1055 C CG  . PRO A 1 154 ? -86.68553 -15.62771 96.34490  1.000 114.57335 ? 141 PRO A CG  1 
ATOM   1056 C CD  . PRO A 1 154 ? -86.48052 -14.74806 97.54414  1.000 109.67989 ? 141 PRO A CD  1 
ATOM   1057 N N   . GLY A 1 155 ? -88.43973 -11.96247 94.25464  1.000 104.85074 ? 142 GLY A N   1 
ATOM   1058 C CA  . GLY A 1 155 ? -89.53321 -11.03435 94.01089  1.000 113.58756 ? 142 GLY A CA  1 
ATOM   1059 C C   . GLY A 1 155 ? -89.34964 -9.66829  94.63730  1.000 124.04270 ? 142 GLY A C   1 
ATOM   1060 O O   . GLY A 1 155 ? -90.33883 -9.01265  94.98268  1.000 129.99694 ? 142 GLY A O   1 
ATOM   1061 N N   . GLN A 1 156 ? -88.10856 -9.21652  94.79377  1.000 126.64846 ? 143 GLN A N   1 
ATOM   1062 C CA  . GLN A 1 156 ? -87.80459 -7.89661  95.32842  1.000 128.24500 ? 143 GLN A CA  1 
ATOM   1063 C C   . GLN A 1 156 ? -86.72140 -7.27878  94.44802  1.000 132.08219 ? 143 GLN A C   1 
ATOM   1064 O O   . GLN A 1 156 ? -86.31053 -7.86181  93.43837  1.000 122.27787 ? 143 GLN A O   1 
ATOM   1065 C CB  . GLN A 1 156 ? -87.41604 -7.99280  96.81626  1.000 118.45776 ? 143 GLN A CB  1 
ATOM   1066 C CG  . GLN A 1 156 ? -85.93089 -8.20342  97.12368  1.000 127.45819 ? 143 GLN A CG  1 
ATOM   1067 C CD  . GLN A 1 156 ? -85.65411 -8.39056  98.61200  1.000 117.32638 ? 143 GLN A CD  1 
ATOM   1068 O OE1 . GLN A 1 156 ? -86.52387 -8.82504  99.36748  1.000 107.00892 ? 143 GLN A OE1 1 
ATOM   1069 N NE2 . GLN A 1 156 ? -84.43834 -8.05795  99.03668  1.000 112.46187 ? 143 GLN A NE2 1 
ATOM   1070 N N   . SER A 1 157 ? -86.27351 -6.07587  94.80042  1.000 134.86126 ? 144 SER A N   1 
ATOM   1071 C CA  . SER A 1 157 ? -85.33431 -5.33296  93.96631  1.000 125.15813 ? 144 SER A CA  1 
ATOM   1072 C C   . SER A 1 157 ? -84.17049 -4.83107  94.80733  1.000 129.83076 ? 144 SER A C   1 
ATOM   1073 O O   . SER A 1 157 ? -84.36388 -4.02319  95.72117  1.000 131.84491 ? 144 SER A O   1 
ATOM   1074 C CB  . SER A 1 157 ? -86.04132 -4.17087  93.26947  1.000 120.57815 ? 144 SER A CB  1 
ATOM   1075 O OG  . SER A 1 157 ? -87.33553 -4.56684  92.85161  1.000 123.95601 ? 144 SER A OG  1 
ATOM   1076 N N   . ILE A 1 158 ? -82.96534 -5.30062  94.48627  1.000 126.68715 ? 145 ILE A N   1 
ATOM   1077 C CA  . ILE A 1 158 ? -81.73945 -4.85875  95.13432  1.000 121.19007 ? 145 ILE A CA  1 
ATOM   1078 C C   . ILE A 1 158 ? -80.82288 -4.29981  94.05199  1.000 111.69889 ? 145 ILE A C   1 
ATOM   1079 O O   . ILE A 1 158 ? -80.94867 -4.62712  92.86904  1.000 106.77424 ? 145 ILE A O   1 
ATOM   1080 C CB  . ILE A 1 158 ? -81.05282 -5.99717  95.91932  1.000 121.09303 ? 145 ILE A CB  1 
ATOM   1081 C CG1 . ILE A 1 158 ? -80.26852 -5.44602  97.11386  1.000 117.93982 ? 145 ILE A CG1 1 
ATOM   1082 C CG2 . ILE A 1 158 ? -80.16948 -6.82414  94.99642  1.000 117.31408 ? 145 ILE A CG2 1 
ATOM   1083 C CD1 . ILE A 1 158 ? -81.14034 -5.01539  98.28908  1.000 102.58871 ? 145 ILE A CD1 1 
ATOM   1084 N N   . THR A 1 159 ? -79.89531 -3.43762  94.46759  1.000 105.02403 ? 146 THR A N   1 
ATOM   1085 C CA  . THR A 1 159 ? -79.08617 -2.67060  93.52800  1.000 96.84187  ? 146 THR A CA  1 
ATOM   1086 C C   . THR A 1 159 ? -77.63115 -2.63769  93.98343  1.000 90.49212  ? 146 THR A C   1 
ATOM   1087 O O   . THR A 1 159 ? -77.35136 -2.56517  95.18351  1.000 89.64004  ? 146 THR A O   1 
ATOM   1088 C CB  . THR A 1 159 ? -79.63683 -1.24468  93.38431  1.000 102.34523 ? 146 THR A CB  1 
ATOM   1089 O OG1 . THR A 1 159 ? -80.95972 -1.30170  92.83746  1.000 113.00544 ? 146 THR A OG1 1 
ATOM   1090 C CG2 . THR A 1 159 ? -78.76140 -0.40821  92.46147  1.000 93.86701  ? 146 THR A CG2 1 
ATOM   1091 N N   . ILE A 1 160 ? -76.70743 -2.67668  93.01698  1.000 85.76753  ? 147 ILE A N   1 
ATOM   1092 C CA  . ILE A 1 160 ? -75.27542 -2.79781  93.27609  1.000 82.39199  ? 147 ILE A CA  1 
ATOM   1093 C C   . ILE A 1 160 ? -74.58434 -1.48433  92.93118  1.000 76.90143  ? 147 ILE A C   1 
ATOM   1094 O O   . ILE A 1 160 ? -74.95187 -0.81204  91.95887  1.000 75.48901  ? 147 ILE A O   1 
ATOM   1095 C CB  . ILE A 1 160 ? -74.67663 -3.96934  92.47267  1.000 67.95586  ? 147 ILE A CB  1 
ATOM   1096 C CG1 . ILE A 1 160 ? -75.49867 -5.23767  92.71725  1.000 64.36676  ? 147 ILE A CG1 1 
ATOM   1097 C CG2 . ILE A 1 160 ? -73.20791 -4.17825  92.82622  1.000 75.88748  ? 147 ILE A CG2 1 
ATOM   1098 C CD1 . ILE A 1 160 ? -74.97498 -6.10315  93.84418  1.000 77.00332  ? 147 ILE A CD1 1 
ATOM   1099 N N   . SER A 1 161 ? -73.56591 -1.13377  93.71660  1.000 75.98156  ? 148 SER A N   1 
ATOM   1100 C CA  . SER A 1 161 ? -72.87996 0.14890   93.60775  1.000 67.73471  ? 148 SER A CA  1 
ATOM   1101 C C   . SER A 1 161 ? -71.48606 -0.04619  93.03087  1.000 67.93933  ? 148 SER A C   1 
ATOM   1102 O O   . SER A 1 161 ? -70.64252 -0.70672  93.64695  1.000 71.59291  ? 148 SER A O   1 
ATOM   1103 C CB  . SER A 1 161 ? -72.78944 0.82842   94.97269  1.000 67.77549  ? 148 SER A CB  1 
ATOM   1104 O OG  . SER A 1 161 ? -74.05204 0.84935   95.60326  1.000 76.58708  ? 148 SER A OG  1 
ATOM   1105 N N   . CYS A 1 162 ? -71.24625 0.53566   91.86103  1.000 70.62006  ? 149 CYS A N   1 
ATOM   1106 C CA  . CYS A 1 162 ? -69.91600 0.59921   91.26435  1.000 75.71707  ? 149 CYS A CA  1 
ATOM   1107 C C   . CYS A 1 162 ? -69.44967 2.05018   91.32501  1.000 77.51886  ? 149 CYS A C   1 
ATOM   1108 O O   . CYS A 1 162 ? -69.93355 2.89662   90.56420  1.000 79.39637  ? 149 CYS A O   1 
ATOM   1109 C CB  . CYS A 1 162 ? -69.92958 0.07458   89.82926  1.000 72.49382  ? 149 CYS A CB  1 
ATOM   1110 S SG  . CYS A 1 162 ? -68.31957 0.08335   88.99512  1.000 60.83100  ? 149 CYS A SG  1 
ATOM   1111 N N   . THR A 1 163 ? -68.52181 2.33789   92.23584  1.000 74.28653  ? 150 THR A N   1 
ATOM   1112 C CA  . THR A 1 163 ? -68.09972 3.70334   92.52791  1.000 72.32219  ? 150 THR A CA  1 
ATOM   1113 C C   . THR A 1 163 ? -66.70308 3.95208   91.96848  1.000 74.55951  ? 150 THR A C   1 
ATOM   1114 O O   . THR A 1 163 ? -65.75232 3.24110   92.31536  1.000 68.89074  ? 150 THR A O   1 
ATOM   1115 C CB  . THR A 1 163 ? -68.12179 3.97640   94.03223  1.000 75.42024  ? 150 THR A CB  1 
ATOM   1116 O OG1 . THR A 1 163 ? -69.40572 3.62537   94.56317  1.000 85.39364  ? 150 THR A OG1 1 
ATOM   1117 C CG2 . THR A 1 163 ? -67.86321 5.45369   94.29933  1.000 77.72977  ? 150 THR A CG2 1 
ATOM   1118 N N   . GLY A 1 164 ? -66.58982 4.96584   91.10987  1.000 83.74352  ? 151 GLY A N   1 
ATOM   1119 C CA  . GLY A 1 164 ? -65.32372 5.42540   90.57101  1.000 83.89409  ? 151 GLY A CA  1 
ATOM   1120 C C   . GLY A 1 164 ? -65.09962 6.88095   90.92548  1.000 89.89264  ? 151 GLY A C   1 
ATOM   1121 O O   . GLY A 1 164 ? -65.80166 7.41123   91.79009  1.000 95.90475  ? 151 GLY A O   1 
ATOM   1122 N N   . ALA A 1 165 ? -64.14649 7.55589   90.26600  1.000 88.59392  ? 152 ALA A N   1 
ATOM   1123 C CA  . ALA A 1 165 ? -63.82387 8.93210   90.66017  1.000 96.72379  ? 152 ALA A CA  1 
ATOM   1124 C C   . ALA A 1 165 ? -63.39931 9.72930   89.42012  1.000 90.11019  ? 152 ALA A C   1 
ATOM   1125 O O   . ALA A 1 165 ? -62.21307 9.87995   89.12046  1.000 102.11571 ? 152 ALA A O   1 
ATOM   1126 C CB  . ALA A 1 165 ? -62.74325 8.96407   91.74127  1.000 99.42806  ? 152 ALA A CB  1 
ATOM   1127 N N   . SER A 1 166 ? -64.39808 10.23804  88.69481  1.000 76.71538  ? 153 SER A N   1 
ATOM   1128 C CA  . SER A 1 166 ? -64.20931 11.20687  87.61595  1.000 81.62116  ? 153 SER A CA  1 
ATOM   1129 C C   . SER A 1 166 ? -63.45995 10.64888  86.40687  1.000 86.94351  ? 153 SER A C   1 
ATOM   1130 O O   . SER A 1 166 ? -64.00830 10.62503  85.29986  1.000 86.54968  ? 153 SER A O   1 
ATOM   1131 C CB  . SER A 1 166 ? -63.49250 12.45135  88.14510  1.000 83.48389  ? 153 SER A CB  1 
ATOM   1132 O OG  . SER A 1 166 ? -63.01756 13.25074  87.07892  1.000 87.06957  ? 153 SER A OG  1 
ATOM   1133 N N   . SER A 1 167 A -62.20553 10.22266  86.59115  1.000 85.61439  ? 153 SER A N   1 
ATOM   1134 C CA  . SER A 1 167 A -61.44839 9.65824   85.47457  1.000 73.07106  ? 153 SER A CA  1 
ATOM   1135 C C   . SER A 1 167 A -62.11996 8.40541   84.92670  1.000 74.26135  ? 153 SER A C   1 
ATOM   1136 O O   . SER A 1 167 A -62.16572 8.19789   83.70826  1.000 71.24575  ? 153 SER A O   1 
ATOM   1137 C CB  . SER A 1 167 A -60.01841 9.35135   85.91129  1.000 67.01799  ? 153 SER A CB  1 
ATOM   1138 O OG  . SER A 1 167 A -59.32213 10.54726  86.20300  1.000 78.57923  ? 153 SER A OG  1 
ATOM   1139 N N   . ASP A 1 168 B -62.64289 7.56114   85.81062  1.000 82.23458  ? 153 ASP A N   1 
ATOM   1140 C CA  . ASP A 1 168 B -63.41590 6.38533   85.43826  1.000 78.47991  ? 153 ASP A CA  1 
ATOM   1141 C C   . ASP A 1 168 B -64.87681 6.58440   85.82775  1.000 86.28551  ? 153 ASP A C   1 
ATOM   1142 O O   . ASP A 1 168 B -65.17265 7.14363   86.88929  1.000 96.40681  ? 153 ASP A O   1 
ATOM   1143 C CB  . ASP A 1 168 B -62.85267 5.12113   86.10762  1.000 86.08548  ? 153 ASP A CB  1 
ATOM   1144 C CG  . ASP A 1 168 B -62.50010 5.33247   87.57816  1.000 104.95639 ? 153 ASP A CG  1 
ATOM   1145 O OD1 . ASP A 1 168 B -62.72498 6.44549   88.09974  1.000 99.43736  ? 153 ASP A OD1 1 
ATOM   1146 O OD2 . ASP A 1 168 B -61.99602 4.37972   88.21501  1.000 115.22540 ? 153 ASP A OD2 1 
ATOM   1147 N N   . VAL A 1 169 C -65.78657 6.15009   84.95065  1.000 79.29130  ? 153 VAL A N   1 
ATOM   1148 C CA  . VAL A 1 169 C -67.23289 6.18848   85.18536  1.000 84.80724  ? 153 VAL A CA  1 
ATOM   1149 C C   . VAL A 1 169 C -67.75060 7.62285   85.21893  1.000 84.48264  ? 153 VAL A C   1 
ATOM   1150 O O   . VAL A 1 169 C -68.66965 7.98100   84.47297  1.000 86.54722  ? 153 VAL A O   1 
ATOM   1151 C CB  . VAL A 1 169 C -67.61733 5.44769   86.48301  1.000 74.31931  ? 153 VAL A CB  1 
ATOM   1152 C CG1 . VAL A 1 169 C -69.08739 5.66401   86.80674  1.000 66.07034  ? 153 VAL A CG1 1 
ATOM   1153 C CG2 . VAL A 1 169 C -67.30385 3.96911   86.36520  1.000 75.17859  ? 153 VAL A CG2 1 
ATOM   1154 N N   . GLY A 1 170 ? -67.17575 8.44744   86.08993  1.000 80.48607  ? 154 GLY A N   1 
ATOM   1155 C CA  . GLY A 1 170 ? -67.64461 9.80764   86.27322  1.000 78.16125  ? 154 GLY A CA  1 
ATOM   1156 C C   . GLY A 1 170 ? -67.56873 10.66819  85.02941  1.000 86.21755  ? 154 GLY A C   1 
ATOM   1157 O O   . GLY A 1 170 ? -68.58870 11.16931  84.54865  1.000 98.19598  ? 154 GLY A O   1 
ATOM   1158 N N   . GLY A 1 171 ? -66.36103 10.84476  84.49603  1.000 82.83764  ? 155 GLY A N   1 
ATOM   1159 C CA  . GLY A 1 171 ? -66.19372 11.71511  83.34730  1.000 95.74876  ? 155 GLY A CA  1 
ATOM   1160 C C   . GLY A 1 171 ? -66.76307 11.14515  82.06474  1.000 101.62747 ? 155 GLY A C   1 
ATOM   1161 O O   . GLY A 1 171 ? -67.23332 11.89692  81.20537  1.000 106.59865 ? 155 GLY A O   1 
ATOM   1162 N N   . TYR A 1 172 ? -66.73907 9.82512   81.91497  1.000 89.18003  ? 156 TYR A N   1 
ATOM   1163 C CA  . TYR A 1 172 ? -67.12730 9.17308   80.67540  1.000 74.35305  ? 156 TYR A CA  1 
ATOM   1164 C C   . TYR A 1 172 ? -68.40977 8.39531   80.90555  1.000 80.24588  ? 156 TYR A C   1 
ATOM   1165 O O   . TYR A 1 172 ? -68.47125 7.55649   81.80901  1.000 85.69176  ? 156 TYR A O   1 
ATOM   1166 C CB  . TYR A 1 172 ? -66.03788 8.21449   80.20223  1.000 59.91060  ? 156 TYR A CB  1 
ATOM   1167 C CG  . TYR A 1 172 ? -64.73208 8.87849   79.87241  1.000 62.52790  ? 156 TYR A CG  1 
ATOM   1168 C CD1 . TYR A 1 172 ? -63.85769 9.24382   80.87623  1.000 67.38606  ? 156 TYR A CD1 1 
ATOM   1169 C CD2 . TYR A 1 172 ? -64.37174 9.14152   78.56182  1.000 72.57513  ? 156 TYR A CD2 1 
ATOM   1170 C CE1 . TYR A 1 172 ? -62.66795 9.85127   80.58558  1.000 69.14815  ? 156 TYR A CE1 1 
ATOM   1171 C CE2 . TYR A 1 172 ? -63.17293 9.75223   78.26053  1.000 70.99261  ? 156 TYR A CE2 1 
ATOM   1172 C CZ  . TYR A 1 172 ? -62.32485 10.10360  79.27551  1.000 65.40802  ? 156 TYR A CZ  1 
ATOM   1173 O OH  . TYR A 1 172 ? -61.12796 10.71256  78.97965  1.000 72.32196  ? 156 TYR A OH  1 
ATOM   1174 N N   . ASP A 1 173 ? -69.41984 8.64786   80.07835  1.000 86.02310  ? 157 ASP A N   1 
ATOM   1175 C CA  . ASP A 1 173 ? -70.59292 7.78561   80.08762  1.000 86.00108  ? 157 ASP A CA  1 
ATOM   1176 C C   . ASP A 1 173 ? -70.23920 6.46365   79.40356  1.000 83.13488  ? 157 ASP A C   1 
ATOM   1177 O O   . ASP A 1 173 ? -70.83816 6.08923   78.38873  1.000 86.12311  ? 157 ASP A O   1 
ATOM   1178 C CB  . ASP A 1 173 ? -71.78993 8.47752   79.42178  1.000 96.32059  ? 157 ASP A CB  1 
ATOM   1179 C CG  . ASP A 1 173 ? -71.41563 9.22042   78.14112  1.000 117.15890 ? 157 ASP A CG  1 
ATOM   1180 O OD1 . ASP A 1 173 ? -70.30408 9.00458   77.60966  1.000 117.24002 ? 157 ASP A OD1 1 
ATOM   1181 O OD2 . ASP A 1 173 ? -72.24638 10.02209  77.65573  1.000 127.89170 ? 157 ASP A OD2 1 
ATOM   1182 N N   . TYR A 1 174 ? -69.23452 5.75954   79.95998  1.000 74.99365  ? 158 TYR A N   1 
ATOM   1183 C CA  . TYR A 1 174 ? -68.67874 4.50922   79.42413  1.000 69.59005  ? 158 TYR A CA  1 
ATOM   1184 C C   . TYR A 1 174 ? -68.57977 3.51283   80.57995  1.000 68.14931  ? 158 TYR A C   1 
ATOM   1185 O O   . TYR A 1 174 ? -67.51503 3.36634   81.18085  1.000 62.80170  ? 158 TYR A O   1 
ATOM   1186 C CB  . TYR A 1 174 ? -67.28625 4.72197   78.78169  1.000 66.78020  ? 158 TYR A CB  1 
ATOM   1187 C CG  . TYR A 1 174 ? -67.23368 5.43827   77.44621  1.000 77.57796  ? 158 TYR A CG  1 
ATOM   1188 C CD1 . TYR A 1 174 ? -68.23848 5.28414   76.49826  1.000 84.29122  ? 158 TYR A CD1 1 
ATOM   1189 C CD2 . TYR A 1 174 ? -66.14791 6.24304   77.12181  1.000 76.64411  ? 158 TYR A CD2 1 
ATOM   1190 C CE1 . TYR A 1 174 ? -68.16760 5.93746   75.27324  1.000 88.54960  ? 158 TYR A CE1 1 
ATOM   1191 C CE2 . TYR A 1 174 ? -66.06972 6.89384   75.90940  1.000 71.65262  ? 158 TYR A CE2 1 
ATOM   1192 C CZ  . TYR A 1 174 ? -67.07631 6.74110   74.98876  1.000 76.53565  ? 158 TYR A CZ  1 
ATOM   1193 O OH  . TYR A 1 174 ? -66.97564 7.40233   73.78588  1.000 75.14542  ? 158 TYR A OH  1 
ATOM   1194 N N   . VAL A 1 175 ? -69.67330 2.81957   80.88831  1.000 72.86126  ? 159 VAL A N   1 
ATOM   1195 C CA  . VAL A 1 175 ? -69.67979 1.83185   81.96224  1.000 60.57399  ? 159 VAL A CA  1 
ATOM   1196 C C   . VAL A 1 175 ? -70.37603 0.56822   81.47937  1.000 59.21674  ? 159 VAL A C   1 
ATOM   1197 O O   . VAL A 1 175 ? -71.48981 0.63011   80.94729  1.000 65.77233  ? 159 VAL A O   1 
ATOM   1198 C CB  . VAL A 1 175 ? -70.36419 2.36042   83.23674  1.000 55.98432  ? 159 VAL A CB  1 
ATOM   1199 C CG1 . VAL A 1 175 ? -70.12703 1.39881   84.38471  1.000 59.88844  ? 159 VAL A CG1 1 
ATOM   1200 C CG2 . VAL A 1 175 ? -69.85600 3.74964   83.59108  1.000 64.05115  ? 159 VAL A CG2 1 
ATOM   1201 N N   . SER A 1 176 ? -69.73069 -0.57649  81.68965  1.000 57.04121  ? 160 SER A N   1 
ATOM   1202 C CA  . SER A 1 176 ? -70.28157 -1.87197  81.32765  1.000 58.98955  ? 160 SER A CA  1 
ATOM   1203 C C   . SER A 1 176 ? -70.50040 -2.73325  82.56496  1.000 61.23432  ? 160 SER A C   1 
ATOM   1204 O O   . SER A 1 176 ? -69.90720 -2.50917  83.62408  1.000 63.82629  ? 160 SER A O   1 
ATOM   1205 C CB  . SER A 1 176 ? -69.36938 -2.61164  80.34759  1.000 66.71114  ? 160 SER A CB  1 
ATOM   1206 O OG  . SER A 1 176 ? -69.17895 -1.84812  79.17332  1.000 84.32235  ? 160 SER A OG  1 
ATOM   1207 N N   . TRP A 1 177 ? -71.34928 -3.74763  82.40379  1.000 65.72202  ? 161 TRP A N   1 
ATOM   1208 C CA  . TRP A 1 177 ? -71.76125 -4.60886  83.50481  1.000 67.53054  ? 161 TRP A CA  1 
ATOM   1209 C C   . TRP A 1 177 ? -71.83509 -6.04770  83.01498  1.000 71.06194  ? 161 TRP A C   1 
ATOM   1210 O O   . TRP A 1 177 ? -72.41919 -6.31718  81.96007  1.000 75.66158  ? 161 TRP A O   1 
ATOM   1211 C CB  . TRP A 1 177 ? -73.11929 -4.16940  84.06408  1.000 69.16605  ? 161 TRP A CB  1 
ATOM   1212 C CG  . TRP A 1 177 ? -73.07216 -2.88533  84.85174  1.000 67.97019  ? 161 TRP A CG  1 
ATOM   1213 C CD1 . TRP A 1 177 ? -73.19740 -1.62000  84.35538  1.000 74.10638  ? 161 TRP A CD1 1 
ATOM   1214 C CD2 . TRP A 1 177 ? -72.90170 -2.74183  86.27031  1.000 68.47462  ? 161 TRP A CD2 1 
ATOM   1215 N NE1 . TRP A 1 177 ? -73.11050 -0.69907  85.37179  1.000 73.88827  ? 161 TRP A NE1 1 
ATOM   1216 C CE2 . TRP A 1 177 ? -72.92883 -1.36113  86.55673  1.000 72.90418  ? 161 TRP A CE2 1 
ATOM   1217 C CE3 . TRP A 1 177 ? -72.72554 -3.64374  87.32321  1.000 71.21618  ? 161 TRP A CE3 1 
ATOM   1218 C CZ2 . TRP A 1 177 ? -72.78778 -0.86257  87.85041  1.000 74.98027  ? 161 TRP A CZ2 1 
ATOM   1219 C CZ3 . TRP A 1 177 ? -72.58597 -3.14538  88.60802  1.000 75.37388  ? 161 TRP A CZ3 1 
ATOM   1220 C CH2 . TRP A 1 177 ? -72.62083 -1.76891  88.86006  1.000 74.47015  ? 161 TRP A CH2 1 
ATOM   1221 N N   . TYR A 1 178 ? -71.26354 -6.97039  83.78890  1.000 61.63771  ? 162 TYR A N   1 
ATOM   1222 C CA  . TYR A 1 178 ? -71.13718 -8.35873  83.36741  1.000 67.53441  ? 162 TYR A CA  1 
ATOM   1223 C C   . TYR A 1 178 ? -71.64561 -9.32373  84.42912  1.000 63.70692  ? 162 TYR A C   1 
ATOM   1224 O O   . TYR A 1 178 ? -71.49954 -9.08580  85.63213  1.000 57.46569  ? 162 TYR A O   1 
ATOM   1225 C CB  . TYR A 1 178 ? -69.68695 -8.71247  83.02861  1.000 72.49076  ? 162 TYR A CB  1 
ATOM   1226 C CG  . TYR A 1 178 ? -69.00388 -7.74759  82.09135  1.000 68.82118  ? 162 TYR A CG  1 
ATOM   1227 C CD1 . TYR A 1 178 ? -68.34753 -6.62316  82.57327  1.000 68.16737  ? 162 TYR A CD1 1 
ATOM   1228 C CD2 . TYR A 1 178 ? -69.01789 -7.96326  80.72135  1.000 62.56338  ? 162 TYR A CD2 1 
ATOM   1229 C CE1 . TYR A 1 178 ? -67.71784 -5.74319  81.71511  1.000 72.98374  ? 162 TYR A CE1 1 
ATOM   1230 C CE2 . TYR A 1 178 ? -68.39488 -7.09039  79.85974  1.000 68.63297  ? 162 TYR A CE2 1 
ATOM   1231 C CZ  . TYR A 1 178 ? -67.74588 -5.98046  80.35752  1.000 77.75527  ? 162 TYR A CZ  1 
ATOM   1232 O OH  . TYR A 1 178 ? -67.12078 -5.10322  79.49798  1.000 79.89124  ? 162 TYR A OH  1 
ATOM   1233 N N   . GLN A 1 179 ? -72.22044 -10.42732 83.95859  1.000 66.15564  ? 163 GLN A N   1 
ATOM   1234 C CA  . GLN A 1 179 ? -72.71070 -11.51728 84.79061  1.000 61.51645  ? 163 GLN A CA  1 
ATOM   1235 C C   . GLN A 1 179 ? -71.79952 -12.72291 84.59951  1.000 69.64294  ? 163 GLN A C   1 
ATOM   1236 O O   . GLN A 1 179 ? -71.71926 -13.27362 83.49613  1.000 79.30236  ? 163 GLN A O   1 
ATOM   1237 C CB  . GLN A 1 179 ? -74.14954 -11.87349 84.41828  1.000 67.72707  ? 163 GLN A CB  1 
ATOM   1238 C CG  . GLN A 1 179 ? -74.72007 -13.08046 85.14912  1.000 66.37189  ? 163 GLN A CG  1 
ATOM   1239 C CD  . GLN A 1 179 ? -76.05411 -13.53753 84.57790  1.000 73.93496  ? 163 GLN A CD  1 
ATOM   1240 O OE1 . GLN A 1 179 ? -76.26061 -13.53249 83.36237  1.000 93.48524  ? 163 GLN A OE1 1 
ATOM   1241 N NE2 . GLN A 1 179 ? -76.96805 -13.92877 85.45584  1.000 69.45764  ? 163 GLN A NE2 1 
ATOM   1242 N N   . GLN A 1 180 ? -71.11654 -13.13278 85.66595  1.000 66.79291  ? 164 GLN A N   1 
ATOM   1243 C CA  . GLN A 1 180 ? -70.27542 -14.32404 85.64821  1.000 72.60933  ? 164 GLN A CA  1 
ATOM   1244 C C   . GLN A 1 180 ? -70.78994 -15.29887 86.69437  1.000 82.06515  ? 164 GLN A C   1 
ATOM   1245 O O   . GLN A 1 180 ? -70.87806 -14.95538 87.87880  1.000 77.96122  ? 164 GLN A O   1 
ATOM   1246 C CB  . GLN A 1 180 ? -68.80789 -13.98670 85.91179  1.000 70.50728  ? 164 GLN A CB  1 
ATOM   1247 C CG  . GLN A 1 180 ? -67.86105 -15.14732 85.61324  1.000 76.88197  ? 164 GLN A CG  1 
ATOM   1248 C CD  . GLN A 1 180 ? -66.44075 -14.89943 86.10671  1.000 82.92565  ? 164 GLN A CD  1 
ATOM   1249 O OE1 . GLN A 1 180 ? -66.20980 -14.07362 86.99275  1.000 76.24602  ? 164 GLN A OE1 1 
ATOM   1250 N NE2 . GLN A 1 180 ? -65.48197 -15.61904 85.53175  1.000 84.55822  ? 164 GLN A NE2 1 
ATOM   1251 N N   . HIS A 1 181 ? -71.12426 -16.51916 86.25349  1.000 89.90909  ? 165 HIS A N   1 
ATOM   1252 C CA  . HIS A 1 181 ? -71.58919 -17.59530 87.11459  1.000 91.86859  ? 165 HIS A CA  1 
ATOM   1253 C C   . HIS A 1 181 ? -70.40803 -18.42039 87.61473  1.000 92.16480  ? 165 HIS A C   1 
ATOM   1254 O O   . HIS A 1 181 ? -69.39900 -18.55240 86.91365  1.000 95.66599  ? 165 HIS A O   1 
ATOM   1255 C CB  . HIS A 1 181 ? -72.56572 -18.49415 86.36076  1.000 89.23732  ? 165 HIS A CB  1 
ATOM   1256 C CG  . HIS A 1 181 ? -73.97005 -17.97725 86.35126  1.000 87.77607  ? 165 HIS A CG  1 
ATOM   1257 N ND1 . HIS A 1 181 ? -74.60840 -17.56853 85.19889  1.000 91.07072  ? 165 HIS A ND1 1 
ATOM   1258 C CD2 . HIS A 1 181 ? -74.85646 -17.79448 87.35808  1.000 86.60642  ? 165 HIS A CD2 1 
ATOM   1259 C CE1 . HIS A 1 181 ? -75.82901 -17.15970 85.49642  1.000 97.34059  ? 165 HIS A CE1 1 
ATOM   1260 N NE2 . HIS A 1 181 ? -76.00421 -17.28648 86.79985  1.000 102.57959 ? 165 HIS A NE2 1 
ATOM   1261 N N   . PRO A 1 182 ? -70.51273 -18.99178 88.83199  1.000 88.22094  ? 166 PRO A N   1 
ATOM   1262 C CA  . PRO A 1 182 ? -69.36119 -19.69070 89.42883  1.000 88.55957  ? 166 PRO A CA  1 
ATOM   1263 C C   . PRO A 1 182 ? -68.78636 -20.79155 88.54731  1.000 89.91972  ? 166 PRO A C   1 
ATOM   1264 O O   . PRO A 1 182 ? -69.39809 -21.85089 88.37562  1.000 91.63288  ? 166 PRO A O   1 
ATOM   1265 C CB  . PRO A 1 182 ? -69.93486 -20.26595 90.73306  1.000 95.77213  ? 166 PRO A CB  1 
ATOM   1266 C CG  . PRO A 1 182 ? -71.43101 -20.21633 90.57164  1.000 91.52108  ? 166 PRO A CG  1 
ATOM   1267 C CD  . PRO A 1 182 ? -71.69629 -19.02735 89.70880  1.000 88.25682  ? 166 PRO A CD  1 
ATOM   1268 N N   . GLY A 1 183 ? -67.60374 -20.54620 87.98630  1.000 86.16261  ? 167 GLY A N   1 
ATOM   1269 C CA  . GLY A 1 183 ? -66.95618 -21.51097 87.11749  1.000 89.76109  ? 167 GLY A CA  1 
ATOM   1270 C C   . GLY A 1 183 ? -67.50780 -21.53059 85.70441  1.000 94.40246  ? 167 GLY A C   1 
ATOM   1271 O O   . GLY A 1 183 ? -67.89793 -22.58794 85.19633  1.000 95.73032  ? 167 GLY A O   1 
ATOM   1272 N N   . LYS A 1 184 ? -67.53573 -20.36780 85.05782  1.000 99.43994  ? 168 LYS A N   1 
ATOM   1273 C CA  . LYS A 1 184 ? -68.05734 -20.23832 83.70226  1.000 94.87640  ? 168 LYS A CA  1 
ATOM   1274 C C   . LYS A 1 184 ? -67.62905 -18.87612 83.17038  1.000 90.82513  ? 168 LYS A C   1 
ATOM   1275 O O   . LYS A 1 184 ? -67.08050 -18.04846 83.90239  1.000 85.82187  ? 168 LYS A O   1 
ATOM   1276 C CB  . LYS A 1 184 ? -69.58265 -20.40054 83.67134  1.000 87.89991  ? 168 LYS A CB  1 
ATOM   1277 C CG  . LYS A 1 184 ? -70.15327 -20.95955 82.36646  1.000 97.15041  ? 168 LYS A CG  1 
ATOM   1278 C CD  . LYS A 1 184 ? -69.51044 -22.28370 81.98341  1.000 106.14581 ? 168 LYS A CD  1 
ATOM   1279 C CE  . LYS A 1 184 ? -69.57528 -22.53026 80.47718  1.000 117.37090 ? 168 LYS A CE  1 
ATOM   1280 N NZ  . LYS A 1 184 ? -68.74564 -21.56146 79.69697  1.000 113.91735 ? 168 LYS A NZ  1 
ATOM   1281 N N   . ALA A 1 185 ? -67.88966 -18.65150 81.88461  1.000 93.42814  ? 169 ALA A N   1 
ATOM   1282 C CA  . ALA A 1 185 ? -67.49097 -17.41109 81.24084  1.000 84.78740  ? 169 ALA A CA  1 
ATOM   1283 C C   . ALA A 1 185 ? -68.40298 -16.25826 81.66488  1.000 85.22122  ? 169 ALA A C   1 
ATOM   1284 O O   . ALA A 1 185 ? -69.54542 -16.47372 82.08045  1.000 89.93666  ? 169 ALA A O   1 
ATOM   1285 C CB  . ALA A 1 185 ? -67.51964 -17.57126 79.72233  1.000 77.01761  ? 169 ALA A CB  1 
ATOM   1286 N N   . PRO A 1 186 ? -67.90238 -15.02282 81.60026  1.000 70.54048  ? 170 PRO A N   1 
ATOM   1287 C CA  . PRO A 1 186 ? -68.76460 -13.85775 81.83964  1.000 63.45875  ? 170 PRO A CA  1 
ATOM   1288 C C   . PRO A 1 186 ? -69.60850 -13.51036 80.62169  1.000 68.40723  ? 170 PRO A C   1 
ATOM   1289 O O   . PRO A 1 186 ? -69.14809 -13.58002 79.47959  1.000 75.67481  ? 170 PRO A O   1 
ATOM   1290 C CB  . PRO A 1 186 ? -67.76005 -12.73605 82.13669  1.000 55.81326  ? 170 PRO A CB  1 
ATOM   1291 C CG  . PRO A 1 186 ? -66.53042 -13.44510 82.58985  1.000 56.34802  ? 170 PRO A CG  1 
ATOM   1292 C CD  . PRO A 1 186 ? -66.47762 -14.67234 81.72827  1.000 63.12029  ? 170 PRO A CD  1 
ATOM   1293 N N   . LYS A 1 187 ? -70.85183 -13.11631 80.88084  1.000 69.88437  ? 171 LYS A N   1 
ATOM   1294 C CA  . LYS A 1 187 ? -71.78251 -12.66491 79.85677  1.000 77.53173  ? 171 LYS A CA  1 
ATOM   1295 C C   . LYS A 1 187 ? -71.98725 -11.16187 79.98804  1.000 76.17955  ? 171 LYS A C   1 
ATOM   1296 O O   . LYS A 1 187 ? -71.89837 -10.60392 81.08519  1.000 72.61579  ? 171 LYS A O   1 
ATOM   1297 C CB  . LYS A 1 187 ? -73.12966 -13.39180 79.97888  1.000 84.96319  ? 171 LYS A CB  1 
ATOM   1298 C CG  . LYS A 1 187 ? -74.15693 -13.06166 78.89920  1.000 87.20233  ? 171 LYS A CG  1 
ATOM   1299 C CD  . LYS A 1 187 ? -75.54554 -13.54041 79.30914  1.000 85.42368  ? 171 LYS A CD  1 
ATOM   1300 C CE  . LYS A 1 187 ? -76.59925 -13.16115 78.28349  1.000 89.00008  ? 171 LYS A CE  1 
ATOM   1301 N NZ  . LYS A 1 187 ? -77.95903 -13.58826 78.71015  1.000 88.83809  ? 171 LYS A NZ  1 
ATOM   1302 N N   . LEU A 1 188 ? -72.25389 -10.50369 78.86392  1.000 77.77402  ? 172 LEU A N   1 
ATOM   1303 C CA  . LEU A 1 188 ? -72.46960 -9.06581  78.88748  1.000 78.82740  ? 172 LEU A CA  1 
ATOM   1304 C C   . LEU A 1 188 ? -73.91112 -8.74558  79.25996  1.000 85.53773  ? 172 LEU A C   1 
ATOM   1305 O O   . LEU A 1 188 ? -74.85098 -9.38579  78.77878  1.000 92.19622  ? 172 LEU A O   1 
ATOM   1306 C CB  . LEU A 1 188 ? -72.13518 -8.44626  77.53235  1.000 75.32976  ? 172 LEU A CB  1 
ATOM   1307 C CG  . LEU A 1 188 ? -72.42871 -6.94464  77.46936  1.000 75.23542  ? 172 LEU A CG  1 
ATOM   1308 C CD1 . LEU A 1 188 ? -71.51279 -6.15140  78.41135  1.000 58.97595  ? 172 LEU A CD1 1 
ATOM   1309 C CD2 . LEU A 1 188 ? -72.34960 -6.43209  76.03747  1.000 94.49743  ? 172 LEU A CD2 1 
ATOM   1310 N N   . LEU A 1 189 ? -74.07968 -7.75163  80.13217  1.000 69.76511  ? 173 LEU A N   1 
ATOM   1311 C CA  . LEU A 1 189 ? -75.39739 -7.29545  80.55183  1.000 62.14429  ? 173 LEU A CA  1 
ATOM   1312 C C   . LEU A 1 189 ? -75.69659 -5.87829  80.07934  1.000 70.12505  ? 173 LEU A C   1 
ATOM   1313 O O   . LEU A 1 189 ? -76.71435 -5.64794  79.41943  1.000 74.42609  ? 173 LEU A O   1 
ATOM   1314 C CB  . LEU A 1 189 ? -75.52008 -7.38278  82.07491  1.000 56.56501  ? 173 LEU A CB  1 
ATOM   1315 C CG  . LEU A 1 189 ? -75.63771 -8.79421  82.63385  1.000 62.59680  ? 173 LEU A CG  1 
ATOM   1316 C CD1 . LEU A 1 189 ? -76.08082 -8.73719  84.08644  1.000 66.39365  ? 173 LEU A CD1 1 
ATOM   1317 C CD2 . LEU A 1 189 ? -76.60201 -9.62366  81.79199  1.000 78.65311  ? 173 LEU A CD2 1 
ATOM   1318 N N   . ILE A 1 190 ? -74.83861 -4.91322  80.40602  1.000 68.78917  ? 174 ILE A N   1 
ATOM   1319 C CA  . ILE A 1 190 ? -75.07949 -3.50913  80.09749  1.000 64.25387  ? 174 ILE A CA  1 
ATOM   1320 C C   . ILE A 1 190 ? -73.84808 -2.92868  79.41777  1.000 63.91983  ? 174 ILE A C   1 
ATOM   1321 O O   . ILE A 1 190 ? -72.72141 -3.14457  79.87524  1.000 64.92968  ? 174 ILE A O   1 
ATOM   1322 C CB  . ILE A 1 190 ? -75.41711 -2.69111  81.35863  1.000 60.44461  ? 174 ILE A CB  1 
ATOM   1323 C CG1 . ILE A 1 190 ? -76.75084 -3.14669  81.95348  1.000 75.80426  ? 174 ILE A CG1 1 
ATOM   1324 C CG2 . ILE A 1 190 ? -75.44595 -1.20190  81.03213  1.000 64.76337  ? 174 ILE A CG2 1 
ATOM   1325 C CD1 . ILE A 1 190 ? -77.93958 -2.90250  81.06463  1.000 92.49122  ? 174 ILE A CD1 1 
ATOM   1326 N N   . TYR A 1 191 ? -74.06483 -2.19016  78.33370  1.000 67.67673  ? 175 TYR A N   1 
ATOM   1327 C CA  . TYR A 1 191 ? -73.03170 -1.41629  77.66334  1.000 67.22095  ? 175 TYR A CA  1 
ATOM   1328 C C   . TYR A 1 191 ? -73.48111 0.03624   77.56172  1.000 75.96785  ? 175 TYR A C   1 
ATOM   1329 O O   . TYR A 1 191 ? -74.63472 0.37285   77.84017  1.000 81.85284  ? 175 TYR A O   1 
ATOM   1330 C CB  . TYR A 1 191 ? -72.69601 -2.01369  76.28776  1.000 65.75602  ? 175 TYR A CB  1 
ATOM   1331 C CG  . TYR A 1 191 ? -73.70514 -1.77026  75.17890  1.000 74.46405  ? 175 TYR A CG  1 
ATOM   1332 C CD1 . TYR A 1 191 ? -74.74443 -2.66781  74.95199  1.000 78.30929  ? 175 TYR A CD1 1 
ATOM   1333 C CD2 . TYR A 1 191 ? -73.60082 -0.66834  74.33717  1.000 76.66185  ? 175 TYR A CD2 1 
ATOM   1334 C CE1 . TYR A 1 191 ? -75.66473 -2.46537  73.92996  1.000 81.91487  ? 175 TYR A CE1 1 
ATOM   1335 C CE2 . TYR A 1 191 ? -74.51852 -0.45441  73.31175  1.000 76.14563  ? 175 TYR A CE2 1 
ATOM   1336 C CZ  . TYR A 1 191 ? -75.54783 -1.35598  73.11174  1.000 83.85108  ? 175 TYR A CZ  1 
ATOM   1337 O OH  . TYR A 1 191 ? -76.45906 -1.14720  72.09436  1.000 101.30775 ? 175 TYR A OH  1 
ATOM   1338 N N   . ASP A 1 192 ? -72.54199 0.89850   77.17120  1.000 72.02127  ? 176 ASP A N   1 
ATOM   1339 C CA  . ASP A 1 192 ? -72.70621 2.34819   77.26944  1.000 79.32776  ? 176 ASP A CA  1 
ATOM   1340 C C   . ASP A 1 192 ? -72.97074 2.75637   78.71705  1.000 85.46556  ? 176 ASP A C   1 
ATOM   1341 O O   . ASP A 1 192 ? -72.03651 2.77684   79.52085  1.000 87.66178  ? 176 ASP A O   1 
ATOM   1342 C CB  . ASP A 1 192 ? -73.79731 2.83538   76.32051  1.000 84.33778  ? 176 ASP A CB  1 
ATOM   1343 C CG  . ASP A 1 192 ? -73.33699 2.82715   74.88973  1.000 94.55230  ? 176 ASP A CG  1 
ATOM   1344 O OD1 . ASP A 1 192 ? -72.13285 2.55427   74.67362  1.000 85.04046  ? 176 ASP A OD1 1 
ATOM   1345 O OD2 . ASP A 1 192 ? -74.16966 3.08921   73.99446  1.000 104.81940 ? 176 ASP A OD2 1 
ATOM   1346 N N   . VAL A 1 193 ? -74.20699 3.10289   79.07576  1.000 84.31606  ? 177 VAL A N   1 
ATOM   1347 C CA  . VAL A 1 193 ? -74.52729 3.32133   80.48826  1.000 78.44811  ? 177 VAL A CA  1 
ATOM   1348 C C   . VAL A 1 193 ? -75.81892 2.61062   80.85662  1.000 82.36641  ? 177 VAL A C   1 
ATOM   1349 O O   . VAL A 1 193 ? -76.01171 2.21100   82.01041  1.000 76.51668  ? 177 VAL A O   1 
ATOM   1350 C CB  . VAL A 1 193 ? -74.63171 4.81523   80.85273  1.000 81.82318  ? 177 VAL A CB  1 
ATOM   1351 C CG1 . VAL A 1 193 ? -73.32324 5.51709   80.62805  1.000 80.37621  ? 177 VAL A CG1 1 
ATOM   1352 C CG2 . VAL A 1 193 ? -75.73775 5.48535   80.04946  1.000 89.88386  ? 177 VAL A CG2 1 
ATOM   1353 N N   . SER A 1 194 ? -76.72199 2.47600   79.89022  1.000 83.13231  ? 178 SER A N   1 
ATOM   1354 C CA  . SER A 1 194 ? -77.99863 1.82581   80.13934  1.000 84.22125  ? 178 SER A CA  1 
ATOM   1355 C C   . SER A 1 194 ? -78.42196 0.88249   79.02974  1.000 83.89099  ? 178 SER A C   1 
ATOM   1356 O O   . SER A 1 194 ? -79.36355 0.11253   79.23735  1.000 94.05774  ? 178 SER A O   1 
ATOM   1357 C CB  . SER A 1 194 ? -79.10450 2.87103   80.34984  1.000 94.71600  ? 178 SER A CB  1 
ATOM   1358 O OG  . SER A 1 194 ? -80.33066 2.24617   80.69042  1.000 100.80213 ? 178 SER A OG  1 
ATOM   1359 N N   . ASP A 1 195 ? -77.77326 0.90859   77.87015  1.000 76.41915  ? 179 ASP A N   1 
ATOM   1360 C CA  . ASP A 1 195 ? -78.14216 0.01961   76.77927  1.000 80.97125  ? 179 ASP A CA  1 
ATOM   1361 C C   . ASP A 1 195 ? -77.73460 -1.41797  77.09558  1.000 76.72144  ? 179 ASP A C   1 
ATOM   1362 O O   . ASP A 1 195 ? -76.77022 -1.66792  77.82400  1.000 76.52229  ? 179 ASP A O   1 
ATOM   1363 C CB  . ASP A 1 195 ? -77.48082 0.48100   75.48049  1.000 89.84805  ? 179 ASP A CB  1 
ATOM   1364 C CG  . ASP A 1 195 ? -77.73281 1.94810   75.18747  1.000 95.67164  ? 179 ASP A CG  1 
ATOM   1365 O OD1 . ASP A 1 195 ? -78.54378 2.56546   75.91370  1.000 104.20404 ? 179 ASP A OD1 1 
ATOM   1366 O OD2 . ASP A 1 195 ? -77.11036 2.48341   74.24165  1.000 89.51818  ? 179 ASP A OD2 1 
ATOM   1367 N N   . ARG A 1 196 ? -78.48053 -2.36975  76.54016  1.000 75.70753  ? 180 ARG A N   1 
ATOM   1368 C CA  . ARG A 1 196 ? -78.21233 -3.78127  76.76239  1.000 71.11367  ? 180 ARG A CA  1 
ATOM   1369 C C   . ARG A 1 196 ? -78.22212 -4.52964  75.43951  1.000 79.38717  ? 180 ARG A C   1 
ATOM   1370 O O   . ARG A 1 196 ? -78.93446 -4.14655  74.50692  1.000 87.43753  ? 180 ARG A O   1 
ATOM   1371 C CB  . ARG A 1 196 ? -79.25009 -4.41533  77.70089  1.000 78.24907  ? 180 ARG A CB  1 
ATOM   1372 C CG  . ARG A 1 196 ? -80.69726 -4.14747  77.30953  1.000 95.51463  ? 180 ARG A CG  1 
ATOM   1373 C CD  . ARG A 1 196 ? -81.65340 -5.05665  78.06706  1.000 95.52947  ? 180 ARG A CD  1 
ATOM   1374 N NE  . ARG A 1 196 ? -83.05591 -4.74168  77.82002  1.000 99.17625  ? 180 ARG A NE  1 
ATOM   1375 C CZ  . ARG A 1 196 ? -83.81212 -4.00073  78.61890  1.000 102.31408 ? 180 ARG A CZ  1 
ATOM   1376 N NH1 . ARG A 1 196 ? -83.33079 -3.47210  79.73131  1.000 90.09269  ? 180 ARG A NH1 1 
ATOM   1377 N NH2 . ARG A 1 196 ? -85.08588 -3.79111  78.29676  1.000 113.16996 ? 180 ARG A NH2 1 
ATOM   1378 N N   . PRO A 1 197 ? -77.44912 -5.59809  75.33006  1.000 80.42246  ? 181 PRO A N   1 
ATOM   1379 C CA  . PRO A 1 197 ? -77.44872 -6.40089  74.10604  1.000 87.30647  ? 181 PRO A CA  1 
ATOM   1380 C C   . PRO A 1 197 ? -78.63200 -7.36375  74.09947  1.000 96.54689  ? 181 PRO A C   1 
ATOM   1381 O O   . PRO A 1 197 ? -79.45155 -7.39189  75.01464  1.000 89.57534  ? 181 PRO A O   1 
ATOM   1382 C CB  . PRO A 1 197 ? -76.11136 -7.13740  74.18804  1.000 85.78349  ? 181 PRO A CB  1 
ATOM   1383 C CG  . PRO A 1 197 ? -75.91426 -7.33014  75.65039  1.000 79.33218  ? 181 PRO A CG  1 
ATOM   1384 C CD  . PRO A 1 197 ? -76.44639 -6.07844  76.29782  1.000 76.99371  ? 181 PRO A CD  1 
ATOM   1385 N N   . SER A 1 198 ? -78.70912 -8.15877  73.03695  1.000 98.15472  ? 182 SER A N   1 
ATOM   1386 C CA  . SER A 1 198 ? -79.74891 -9.16754  72.93099  1.000 93.85447  ? 182 SER A CA  1 
ATOM   1387 C C   . SER A 1 198 ? -79.53148 -10.27218 73.96835  1.000 93.04223  ? 182 SER A C   1 
ATOM   1388 O O   . SER A 1 198 ? -78.48222 -10.36957 74.61344  1.000 85.51147  ? 182 SER A O   1 
ATOM   1389 C CB  . SER A 1 198 ? -79.78412 -9.73448  71.51289  1.000 74.48903  ? 182 SER A CB  1 
ATOM   1390 O OG  . SER A 1 198 ? -78.51958 -10.25508 71.13899  1.000 66.40666  ? 182 SER A OG  1 
ATOM   1391 N N   . GLY A 1 199 ? -80.56110 -11.09852 74.14386  1.000 95.50381  ? 183 GLY A N   1 
ATOM   1392 C CA  . GLY A 1 199 ? -80.48929 -12.23628 75.04305  1.000 85.82915  ? 183 GLY A CA  1 
ATOM   1393 C C   . GLY A 1 199 ? -80.42796 -11.80498 76.49059  1.000 83.58553  ? 183 GLY A C   1 
ATOM   1394 O O   . GLY A 1 199 ? -80.11759 -12.59881 77.38593  1.000 96.70337  ? 183 GLY A O   1 
ATOM   1395 N N   . VAL A 1 200 ? -80.72635 -10.53506 76.72769  1.000 81.76447  ? 184 VAL A N   1 
ATOM   1396 C CA  . VAL A 1 200 ? -80.61167 -9.92635  78.04133  1.000 82.57058  ? 184 VAL A CA  1 
ATOM   1397 C C   . VAL A 1 200 ? -82.01131 -9.56527  78.50362  1.000 89.45323  ? 184 VAL A C   1 
ATOM   1398 O O   . VAL A 1 200 ? -82.73860 -8.84708  77.80503  1.000 95.25791  ? 184 VAL A O   1 
ATOM   1399 C CB  . VAL A 1 200 ? -79.69851 -8.69431  78.01226  1.000 80.03073  ? 184 VAL A CB  1 
ATOM   1400 C CG1 . VAL A 1 200 ? -79.91018 -7.87189  79.24832  1.000 78.69190  ? 184 VAL A CG1 1 
ATOM   1401 C CG2 . VAL A 1 200 ? -78.23856 -9.12590  77.88223  1.000 82.56922  ? 184 VAL A CG2 1 
ATOM   1402 N N   . SER A 1 201 ? -82.38437 -10.06988 79.67719  1.000 87.89037  ? 185 SER A N   1 
ATOM   1403 C CA  . SER A 1 201 ? -83.72719 -9.86736  80.20085  1.000 94.51271  ? 185 SER A CA  1 
ATOM   1404 C C   . SER A 1 201 ? -83.99560 -8.39343  80.47351  1.000 97.04557  ? 185 SER A C   1 
ATOM   1405 O O   . SER A 1 201 ? -83.08685 -7.62130  80.78776  1.000 91.43417  ? 185 SER A O   1 
ATOM   1406 C CB  . SER A 1 201 ? -83.91719 -10.66729 81.48561  1.000 86.52142  ? 185 SER A CB  1 
ATOM   1407 O OG  . SER A 1 201 ? -85.16579 -10.36561 82.08244  1.000 75.95883  ? 185 SER A OG  1 
ATOM   1408 N N   . ASN A 1 202 ? -85.27209 -8.01251  80.36247  1.000 106.71133 ? 186 ASN A N   1 
ATOM   1409 C CA  . ASN A 1 202 ? -85.67546 -6.64117  80.65964  1.000 103.51452 ? 186 ASN A CA  1 
ATOM   1410 C C   . ASN A 1 202 ? -85.24164 -6.23916  82.05702  1.000 96.96793  ? 186 ASN A C   1 
ATOM   1411 O O   . ASN A 1 202 ? -84.88118 -5.08323  82.30187  1.000 96.90974  ? 186 ASN A O   1 
ATOM   1412 C CB  . ASN A 1 202 ? -87.19097 -6.50182  80.54315  1.000 102.03589 ? 186 ASN A CB  1 
ATOM   1413 C CG  . ASN A 1 202 ? -87.72009 -6.96736  79.21374  1.000 119.44079 ? 186 ASN A CG  1 
ATOM   1414 O OD1 . ASN A 1 202 ? -86.96393 -7.19751  78.27034  1.000 117.50133 ? 186 ASN A OD1 1 
ATOM   1415 N ND2 . ASN A 1 202 ? -89.03418 -7.12669  79.13405  1.000 134.16550 ? 186 ASN A ND2 1 
ATOM   1416 N N   . ARG A 1 203 ? -85.27449 -7.19498  82.98611  1.000 95.04950  ? 187 ARG A N   1 
ATOM   1417 C CA  . ARG A 1 203 ? -84.96684 -6.93002  84.38726  1.000 103.95770 ? 187 ARG A CA  1 
ATOM   1418 C C   . ARG A 1 203 ? -83.56989 -6.34815  84.57196  1.000 100.74570 ? 187 ARG A C   1 
ATOM   1419 O O   . ARG A 1 203 ? -83.31938 -5.63212  85.55029  1.000 92.44989  ? 187 ARG A O   1 
ATOM   1420 C CB  . ARG A 1 203 ? -85.13349 -8.22739  85.16789  1.000 101.70216 ? 187 ARG A CB  1 
ATOM   1421 C CG  . ARG A 1 203 ? -86.43606 -8.92650  84.83962  1.000 102.10760 ? 187 ARG A CG  1 
ATOM   1422 C CD  . ARG A 1 203 ? -86.51400 -10.27920 85.49727  1.000 101.27643 ? 187 ARG A CD  1 
ATOM   1423 N NE  . ARG A 1 203 ? -85.32890 -11.06020 85.16253  1.000 98.21374  ? 187 ARG A NE  1 
ATOM   1424 C CZ  . ARG A 1 203 ? -84.90368 -12.11882 85.83588  1.000 98.29082  ? 187 ARG A CZ  1 
ATOM   1425 N NH1 . ARG A 1 203 ? -85.54744 -12.56319 86.90097  1.000 105.55625 ? 187 ARG A NH1 1 
ATOM   1426 N NH2 . ARG A 1 203 ? -83.81353 -12.75672 85.41892  1.000 86.02763  ? 187 ARG A NH2 1 
ATOM   1427 N N   . PHE A 1 204 ? -82.64640 -6.65718  83.66376  1.000 96.42065  ? 188 PHE A N   1 
ATOM   1428 C CA  . PHE A 1 204 ? -81.32255 -6.05126  83.69016  1.000 91.64585  ? 188 PHE A CA  1 
ATOM   1429 C C   . PHE A 1 204 ? -81.40829 -4.60009  83.23252  1.000 93.81003  ? 188 PHE A C   1 
ATOM   1430 O O   . PHE A 1 204 ? -81.93491 -4.30993  82.15413  1.000 104.88281 ? 188 PHE A O   1 
ATOM   1431 C CB  . PHE A 1 204 ? -80.35625 -6.83501  82.80257  1.000 90.26470  ? 188 PHE A CB  1 
ATOM   1432 C CG  . PHE A 1 204 ? -80.27559 -8.30218  83.13221  1.000 94.29095  ? 188 PHE A CG  1 
ATOM   1433 C CD1 . PHE A 1 204 ? -79.82732 -8.71935  84.38033  1.000 84.99981  ? 188 PHE A CD1 1 
ATOM   1434 C CD2 . PHE A 1 204 ? -80.63588 -9.26239  82.19330  1.000 96.03534  ? 188 PHE A CD2 1 
ATOM   1435 C CE1 . PHE A 1 204 ? -79.74243 -10.06463 84.68904  1.000 83.30357  ? 188 PHE A CE1 1 
ATOM   1436 C CE2 . PHE A 1 204 ? -80.55177 -10.60972 82.48776  1.000 97.63974  ? 188 PHE A CE2 1 
ATOM   1437 C CZ  . PHE A 1 204 ? -80.10638 -11.01420 83.74050  1.000 95.36066  ? 188 PHE A CZ  1 
ATOM   1438 N N   . SER A 1 205 ? -80.89101 -3.68783  84.05550  1.000 78.92748  ? 189 SER A N   1 
ATOM   1439 C CA  . SER A 1 205 ? -81.00245 -2.26070  83.77640  1.000 79.20359  ? 189 SER A CA  1 
ATOM   1440 C C   . SER A 1 205 ? -80.03788 -1.45887  84.63946  1.000 78.94703  ? 189 SER A C   1 
ATOM   1441 O O   . SER A 1 205 ? -79.98777 -1.65526  85.85533  1.000 83.85196  ? 189 SER A O   1 
ATOM   1442 C CB  . SER A 1 205 ? -82.43871 -1.79555  84.01222  1.000 91.19579  ? 189 SER A CB  1 
ATOM   1443 O OG  . SER A 1 205 ? -82.95870 -2.36438  85.20373  1.000 95.44658  ? 189 SER A OG  1 
ATOM   1444 N N   . GLY A 1 206 ? -79.28796 -0.54291  84.03682  1.000 83.24674  ? 190 GLY A N   1 
ATOM   1445 C CA  . GLY A 1 206 ? -78.24433 0.16969   84.74925  1.000 87.52473  ? 190 GLY A CA  1 
ATOM   1446 C C   . GLY A 1 206 ? -78.29270 1.66776   84.53369  1.000 87.34148  ? 190 GLY A C   1 
ATOM   1447 O O   . GLY A 1 206 ? -78.78636 2.15775   83.51817  1.000 87.72256  ? 190 GLY A O   1 
ATOM   1448 N N   . SER A 1 207 ? -77.73800 2.39559   85.50738  1.000 88.21492  ? 191 SER A N   1 
ATOM   1449 C CA  . SER A 1 207 ? -77.81905 3.85163   85.54561  1.000 89.36441  ? 191 SER A CA  1 
ATOM   1450 C C   . SER A 1 207 ? -76.47794 4.44008   85.97322  1.000 85.04302  ? 191 SER A C   1 
ATOM   1451 O O   . SER A 1 207 ? -75.49841 3.72116   86.19957  1.000 86.26939  ? 191 SER A O   1 
ATOM   1452 C CB  . SER A 1 207 ? -78.93332 4.31876   86.49127  1.000 87.11334  ? 191 SER A CB  1 
ATOM   1453 O OG  . SER A 1 207 ? -78.70333 3.87038   87.81799  1.000 78.20379  ? 191 SER A OG  1 
ATOM   1454 N N   . LYS A 1 208 ? -76.45265 5.76894   86.08737  1.000 81.32000  ? 192 LYS A N   1 
ATOM   1455 C CA  . LYS A 1 208 ? -75.27113 6.52542   86.47513  1.000 81.00497  ? 192 LYS A CA  1 
ATOM   1456 C C   . LYS A 1 208 ? -75.73507 7.82083   87.12406  1.000 79.62044  ? 192 LYS A C   1 
ATOM   1457 O O   . LYS A 1 208 ? -76.74402 8.40241   86.71280  1.000 88.94012  ? 192 LYS A O   1 
ATOM   1458 C CB  . LYS A 1 208 ? -74.36663 6.82013   85.26676  1.000 84.77872  ? 192 LYS A CB  1 
ATOM   1459 C CG  . LYS A 1 208 ? -73.03354 7.50055   85.59432  1.000 70.68421  ? 192 LYS A CG  1 
ATOM   1460 C CD  . LYS A 1 208 ? -72.11802 7.55075   84.36939  1.000 70.94855  ? 192 LYS A CD  1 
ATOM   1461 C CE  . LYS A 1 208 ? -72.53508 8.62513   83.36939  1.000 83.91738  ? 192 LYS A CE  1 
ATOM   1462 N NZ  . LYS A 1 208 ? -72.34307 10.00482  83.89124  1.000 91.33570  ? 192 LYS A NZ  1 
ATOM   1463 N N   . SER A 1 209 ? -75.00516 8.25892   88.14944  1.000 68.51564  ? 193 SER A N   1 
ATOM   1464 C CA  . SER A 1 209 ? -75.32447 9.50948   88.84188  1.000 76.22816  ? 193 SER A CA  1 
ATOM   1465 C C   . SER A 1 209 ? -74.01594 10.07402  89.39409  1.000 79.90581  ? 193 SER A C   1 
ATOM   1466 O O   . SER A 1 209 ? -73.63251 9.79142   90.53154  1.000 75.04734  ? 193 SER A O   1 
ATOM   1467 C CB  . SER A 1 209 ? -76.35392 9.29998   89.94063  1.000 86.69210  ? 193 SER A CB  1 
ATOM   1468 O OG  . SER A 1 209 ? -77.50952 8.66289   89.42993  1.000 97.31594  ? 193 SER A OG  1 
ATOM   1469 N N   . GLY A 1 210 ? -73.34749 10.88069  88.57639  1.000 85.78799  ? 194 GLY A N   1 
ATOM   1470 C CA  . GLY A 1 210 ? -72.09698 11.48151  88.98557  1.000 87.00807  ? 194 GLY A CA  1 
ATOM   1471 C C   . GLY A 1 210 ? -70.94106 10.51331  88.86838  1.000 89.33962  ? 194 GLY A C   1 
ATOM   1472 O O   . GLY A 1 210 ? -70.57935 10.10357  87.76054  1.000 96.30729  ? 194 GLY A O   1 
ATOM   1473 N N   . ASN A 1 211 ? -70.36732 10.12797  90.00787  1.000 83.61674  ? 195 ASN A N   1 
ATOM   1474 C CA  . ASN A 1 211 ? -69.21540 9.23732   90.05364  1.000 81.34075  ? 195 ASN A CA  1 
ATOM   1475 C C   . ASN A 1 211 ? -69.59218 7.77380   90.27083  1.000 85.60449  ? 195 ASN A C   1 
ATOM   1476 O O   . ASN A 1 211 ? -68.70284 6.91727   90.27473  1.000 82.11558  ? 195 ASN A O   1 
ATOM   1477 C CB  . ASN A 1 211 ? -68.24585 9.68689   91.15851  1.000 76.89271  ? 195 ASN A CB  1 
ATOM   1478 C CG  . ASN A 1 211 ? -67.29454 10.77883  90.69481  1.000 88.33395  ? 195 ASN A CG  1 
ATOM   1479 O OD1 . ASN A 1 211 ? -67.31627 11.18159  89.53157  1.000 92.65894  ? 195 ASN A OD1 1 
ATOM   1480 N ND2 . ASN A 1 211 ? -66.44216 11.24917  91.59985  1.000 93.91833  ? 195 ASN A ND2 1 
ATOM   1481 N N   . THR A 1 212 ? -70.87586 7.45649   90.43238  1.000 89.60879  ? 196 THR A N   1 
ATOM   1482 C CA  . THR A 1 212 ? -71.31183 6.10133   90.75069  1.000 79.95621  ? 196 THR A CA  1 
ATOM   1483 C C   . THR A 1 212 ? -72.33342 5.62742   89.72666  1.000 83.94194  ? 196 THR A C   1 
ATOM   1484 O O   . THR A 1 212 ? -73.34914 6.29443   89.49956  1.000 89.55214  ? 196 THR A O   1 
ATOM   1485 C CB  . THR A 1 212 ? -71.90077 6.03534   92.15992  1.000 78.59515  ? 196 THR A CB  1 
ATOM   1486 O OG1 . THR A 1 212 ? -70.91311 6.46981   93.10540  1.000 88.57861  ? 196 THR A OG1 1 
ATOM   1487 C CG2 . THR A 1 212 ? -72.33139 4.61889   92.48474  1.000 78.67533  ? 196 THR A CG2 1 
ATOM   1488 N N   . ALA A 1 213 ? -72.06244 4.47878   89.11470  1.000 77.74752  ? 197 ALA A N   1 
ATOM   1489 C CA  . ALA A 1 213 ? -73.03339 3.78189   88.28871  1.000 76.18353  ? 197 ALA A CA  1 
ATOM   1490 C C   . ALA A 1 213 ? -73.69228 2.68936   89.11895  1.000 73.51186  ? 197 ALA A C   1 
ATOM   1491 O O   . ALA A 1 213 ? -73.11598 2.19579   90.09028  1.000 78.37402  ? 197 ALA A O   1 
ATOM   1492 C CB  . ALA A 1 213 ? -72.37225 3.18070   87.04802  1.000 78.48188  ? 197 ALA A CB  1 
ATOM   1493 N N   . SER A 1 214 ? -74.90994 2.31495   88.73838  1.000 73.96263  ? 198 SER A N   1 
ATOM   1494 C CA  . SER A 1 214 ? -75.66277 1.34703   89.53025  1.000 78.68689  ? 198 SER A CA  1 
ATOM   1495 C C   . SER A 1 214 ? -76.50234 0.47337   88.61080  1.000 79.62618  ? 198 SER A C   1 
ATOM   1496 O O   . SER A 1 214 ? -77.30189 0.98865   87.82320  1.000 78.91133  ? 198 SER A O   1 
ATOM   1497 C CB  . SER A 1 214 ? -76.54757 2.05954   90.55728  1.000 79.10106  ? 198 SER A CB  1 
ATOM   1498 O OG  . SER A 1 214 ? -75.76433 2.79089   91.48811  1.000 67.48616  ? 198 SER A OG  1 
ATOM   1499 N N   . LEU A 1 215 ? -76.31760 -0.84158  88.71477  1.000 77.11100  ? 199 LEU A N   1 
ATOM   1500 C CA  . LEU A 1 215 ? -77.11239 -1.81813  87.98129  1.000 75.87014  ? 199 LEU A CA  1 
ATOM   1501 C C   . LEU A 1 215 ? -78.22031 -2.33939  88.88741  1.000 83.08915  ? 199 LEU A C   1 
ATOM   1502 O O   . LEU A 1 215 ? -77.95612 -2.76390  90.01706  1.000 83.93612  ? 199 LEU A O   1 
ATOM   1503 C CB  . LEU A 1 215 ? -76.23498 -2.97040  87.48204  1.000 72.22097  ? 199 LEU A CB  1 
ATOM   1504 C CG  . LEU A 1 215 ? -76.90400 -4.20458  86.86521  1.000 74.90572  ? 199 LEU A CG  1 
ATOM   1505 C CD1 . LEU A 1 215 ? -77.61619 -3.85564  85.56913  1.000 88.17233  ? 199 LEU A CD1 1 
ATOM   1506 C CD2 . LEU A 1 215 ? -75.87996 -5.30611  86.61807  1.000 57.32567  ? 199 LEU A CD2 1 
ATOM   1507 N N   . THR A 1 216 ? -79.45669 -2.29669  88.39647  1.000 92.62617  ? 200 THR A N   1 
ATOM   1508 C CA  . THR A 1 216 ? -80.61942 -2.68642  89.17958  1.000 96.29442  ? 200 THR A CA  1 
ATOM   1509 C C   . THR A 1 216 ? -81.27712 -3.92093  88.57542  1.000 103.94671 ? 200 THR A C   1 
ATOM   1510 O O   . THR A 1 216 ? -81.21654 -4.15423  87.36337  1.000 97.92508  ? 200 THR A O   1 
ATOM   1511 C CB  . THR A 1 216 ? -81.64276 -1.54224  89.27879  1.000 100.47961 ? 200 THR A CB  1 
ATOM   1512 O OG1 . THR A 1 216 ? -82.35636 -1.41782  88.04350  1.000 123.10559 ? 200 THR A OG1 1 
ATOM   1513 C CG2 . THR A 1 216 ? -80.94315 -0.22484  89.58068  1.000 92.77696  ? 200 THR A CG2 1 
ATOM   1514 N N   . ILE A 1 217 ? -81.91237 -4.70603  89.44020  1.000 114.47829 ? 201 ILE A N   1 
ATOM   1515 C CA  . ILE A 1 217 ? -82.52395 -5.97340  89.05609  1.000 117.69972 ? 201 ILE A CA  1 
ATOM   1516 C C   . ILE A 1 217 ? -83.76367 -6.17851  89.92209  1.000 128.94788 ? 201 ILE A C   1 
ATOM   1517 O O   . ILE A 1 217 ? -83.70989 -6.03554  91.14848  1.000 128.59707 ? 201 ILE A O   1 
ATOM   1518 C CB  . ILE A 1 217 ? -81.51244 -7.13528  89.19197  1.000 105.11865 ? 201 ILE A CB  1 
ATOM   1519 C CG1 . ILE A 1 217 ? -82.01049 -8.40918  88.50462  1.000 96.43350  ? 201 ILE A CG1 1 
ATOM   1520 C CG2 . ILE A 1 217 ? -81.10828 -7.37088  90.65118  1.000 108.37439 ? 201 ILE A CG2 1 
ATOM   1521 C CD1 . ILE A 1 217 ? -82.23663 -8.26274  87.03638  1.000 97.97719  ? 201 ILE A CD1 1 
ATOM   1522 N N   . SER A 1 218 ? -84.89331 -6.47742  89.28292  1.000 122.45992 ? 202 SER A N   1 
ATOM   1523 C CA  . SER A 1 218 ? -86.16091 -6.62312  89.98270  1.000 128.17103 ? 202 SER A CA  1 
ATOM   1524 C C   . SER A 1 218 ? -86.83546 -7.92514  89.57720  1.000 128.68695 ? 202 SER A C   1 
ATOM   1525 O O   . SER A 1 218 ? -86.66447 -8.41563  88.45663  1.000 118.14654 ? 202 SER A O   1 
ATOM   1526 C CB  . SER A 1 218 ? -87.10532 -5.43620  89.71360  1.000 134.49710 ? 202 SER A CB  1 
ATOM   1527 O OG  . SER A 1 218 ? -86.46460 -4.19143  89.94205  1.000 136.51489 ? 202 SER A OG  1 
ATOM   1528 N N   . GLY A 1 219 ? -87.62080 -8.46943  90.50393  1.000 124.94386 ? 203 GLY A N   1 
ATOM   1529 C CA  . GLY A 1 219 ? -88.19578 -9.78581  90.32890  1.000 121.46012 ? 203 GLY A CA  1 
ATOM   1530 C C   . GLY A 1 219 ? -87.10711 -10.83526 90.34647  1.000 121.10544 ? 203 GLY A C   1 
ATOM   1531 O O   . GLY A 1 219 ? -86.88346 -11.52597 89.34667  1.000 112.81652 ? 203 GLY A O   1 
ATOM   1532 N N   . LEU A 1 220 ? -86.41567 -10.94824 91.48003  1.000 116.56804 ? 204 LEU A N   1 
ATOM   1533 C CA  . LEU A 1 220 ? -85.26147 -11.83082 91.57226  1.000 108.35044 ? 204 LEU A CA  1 
ATOM   1534 C C   . LEU A 1 220 ? -85.66571 -13.28541 91.38715  1.000 112.46945 ? 204 LEU A C   1 
ATOM   1535 O O   . LEU A 1 220 ? -86.69555 -13.73631 91.89632  1.000 118.63216 ? 204 LEU A O   1 
ATOM   1536 C CB  . LEU A 1 220 ? -84.55990 -11.65554 92.91887  1.000 104.87973 ? 204 LEU A CB  1 
ATOM   1537 C CG  . LEU A 1 220 ? -83.04489 -11.87778 92.89563  1.000 93.97531  ? 204 LEU A CG  1 
ATOM   1538 C CD1 . LEU A 1 220 ? -82.35787 -10.71408 92.21615  1.000 102.13487 ? 204 LEU A CD1 1 
ATOM   1539 C CD2 . LEU A 1 220 ? -82.49111 -12.08741 94.29929  1.000 104.15027 ? 204 LEU A CD2 1 
ATOM   1540 N N   . GLN A 1 221 ? -84.83801 -14.01730 90.65530  1.000 101.50576 ? 205 GLN A N   1 
ATOM   1541 C CA  . GLN A 1 221 ? -85.04118 -15.42560 90.37463  1.000 109.92940 ? 205 GLN A CA  1 
ATOM   1542 C C   . GLN A 1 221 ? -83.91121 -16.23493 91.01169  1.000 113.60860 ? 205 GLN A C   1 
ATOM   1543 O O   . GLN A 1 221 ? -83.07964 -15.70677 91.76113  1.000 105.15773 ? 205 GLN A O   1 
ATOM   1544 C CB  . GLN A 1 221 ? -85.13527 -15.64021 88.86199  1.000 98.58332  ? 205 GLN A CB  1 
ATOM   1545 C CG  . GLN A 1 221 ? -86.49108 -15.29316 88.26159  1.000 90.60343  ? 205 GLN A CG  1 
ATOM   1546 C CD  . GLN A 1 221 ? -86.63659 -15.78024 86.83379  1.000 105.57624 ? 205 GLN A CD  1 
ATOM   1547 O OE1 . GLN A 1 221 ? -85.72024 -16.38217 86.27509  1.000 113.94719 ? 205 GLN A OE1 1 
ATOM   1548 N NE2 . GLN A 1 221 ? -87.78804 -15.51134 86.23121  1.000 112.80913 ? 205 GLN A NE2 1 
ATOM   1549 N N   . THR A 1 222 ? -83.88910 -17.53320 90.72170  1.000 119.54353 ? 206 THR A N   1 
ATOM   1550 C CA  . THR A 1 222 ? -82.84183 -18.40072 91.24301  1.000 118.04836 ? 206 THR A CA  1 
ATOM   1551 C C   . THR A 1 222 ? -81.60342 -18.39553 90.35628  1.000 122.21788 ? 206 THR A C   1 
ATOM   1552 O O   . THR A 1 222 ? -80.47977 -18.46950 90.86592  1.000 126.09849 ? 206 THR A O   1 
ATOM   1553 C CB  . THR A 1 222 ? -83.36619 -19.83064 91.40101  1.000 129.19939 ? 206 THR A CB  1 
ATOM   1554 O OG1 . THR A 1 222 ? -83.65076 -20.38362 90.10906  1.000 135.89487 ? 206 THR A OG1 1 
ATOM   1555 C CG2 . THR A 1 222 ? -84.63235 -19.84384 92.25250  1.000 120.03147 ? 206 THR A CG2 1 
ATOM   1556 N N   . GLU A 1 223 ? -81.78685 -18.29027 89.03626  1.000 119.03594 ? 207 GLU A N   1 
ATOM   1557 C CA  . GLU A 1 223 ? -80.65725 -18.22784 88.11446  1.000 116.56608 ? 207 GLU A CA  1 
ATOM   1558 C C   . GLU A 1 223 ? -79.75055 -17.03197 88.37016  1.000 110.97921 ? 207 GLU A C   1 
ATOM   1559 O O   . GLU A 1 223 ? -78.64771 -16.98421 87.81378  1.000 113.60930 ? 207 GLU A O   1 
ATOM   1560 C CB  . GLU A 1 223 ? -81.14215 -18.15532 86.66375  1.000 118.92215 ? 207 GLU A CB  1 
ATOM   1561 C CG  . GLU A 1 223 ? -82.34646 -19.01307 86.32897  1.000 122.98698 ? 207 GLU A CG  1 
ATOM   1562 C CD  . GLU A 1 223 ? -82.96845 -18.62735 84.99835  1.000 137.77005 ? 207 GLU A CD  1 
ATOM   1563 O OE1 . GLU A 1 223 ? -82.35127 -17.82727 84.25981  1.000 134.64010 ? 207 GLU A OE1 1 
ATOM   1564 O OE2 . GLU A 1 223 ? -84.07318 -19.12419 84.69071  1.000 150.45260 ? 207 GLU A OE2 1 
ATOM   1565 N N   . ASP A 1 224 ? -80.18380 -16.07296 89.18910  1.000 105.01673 ? 208 ASP A N   1 
ATOM   1566 C CA  . ASP A 1 224 ? -79.50686 -14.79318 89.33098  1.000 101.10343 ? 208 ASP A CA  1 
ATOM   1567 C C   . ASP A 1 224 ? -78.53444 -14.74769 90.50455  1.000 103.04008 ? 208 ASP A C   1 
ATOM   1568 O O   . ASP A 1 224 ? -77.76424 -13.78646 90.61010  1.000 97.57179  ? 208 ASP A O   1 
ATOM   1569 C CB  . ASP A 1 224 ? -80.54814 -13.67128 89.46581  1.000 106.70321 ? 208 ASP A CB  1 
ATOM   1570 C CG  . ASP A 1 224 ? -81.46642 -13.57970 88.24841  1.000 114.50942 ? 208 ASP A CG  1 
ATOM   1571 O OD1 . ASP A 1 224 ? -81.60260 -14.59309 87.53145  1.000 116.66338 ? 208 ASP A OD1 1 
ATOM   1572 O OD2 . ASP A 1 224 ? -82.04946 -12.50170 87.99924  1.000 116.69232 ? 208 ASP A OD2 1 
ATOM   1573 N N   . GLU A 1 225 ? -78.55053 -15.74816 91.38631  1.000 108.41369 ? 209 GLU A N   1 
ATOM   1574 C CA  . GLU A 1 225 ? -77.51260 -15.87148 92.40277  1.000 106.48201 ? 209 GLU A CA  1 
ATOM   1575 C C   . GLU A 1 225 ? -76.16476 -16.09295 91.72636  1.000 106.79146 ? 209 GLU A C   1 
ATOM   1576 O O   . GLU A 1 225 ? -75.90587 -17.17156 91.18024  1.000 107.37818 ? 209 GLU A O   1 
ATOM   1577 C CB  . GLU A 1 225 ? -77.84548 -17.00784 93.37744  1.000 109.58117 ? 209 GLU A CB  1 
ATOM   1578 C CG  . GLU A 1 225 ? -76.84760 -17.17470 94.51027  1.000 119.70068 ? 209 GLU A CG  1 
ATOM   1579 C CD  . GLU A 1 225 ? -77.43380 -17.86897 95.72492  1.000 122.05375 ? 209 GLU A CD  1 
ATOM   1580 O OE1 . GLU A 1 225 ? -78.46272 -18.56276 95.57890  1.000 121.42821 ? 209 GLU A OE1 1 
ATOM   1581 O OE2 . GLU A 1 225 ? -76.86291 -17.71700 96.82744  1.000 114.44998 ? 209 GLU A OE2 1 
ATOM   1582 N N   . ALA A 1 226 ? -75.31150 -15.07217 91.74108  1.000 103.39241 ? 210 ALA A N   1 
ATOM   1583 C CA  . ALA A 1 226 ? -74.03063 -15.11471 91.04011  1.000 99.25112  ? 210 ALA A CA  1 
ATOM   1584 C C   . ALA A 1 226 ? -73.17960 -13.93074 91.49739  1.000 93.30686  ? 210 ALA A C   1 
ATOM   1585 O O   . ALA A 1 226 ? -73.53953 -13.19952 92.42795  1.000 89.49685  ? 210 ALA A O   1 
ATOM   1586 C CB  . ALA A 1 226 ? -74.23052 -15.10482 89.52297  1.000 83.28581  ? 210 ALA A CB  1 
ATOM   1587 N N   . ASP A 1 227 ? -72.03001 -13.76594 90.83879  1.000 79.11065  ? 211 ASP A N   1 
ATOM   1588 C CA  . ASP A 1 227 ? -71.14044 -12.63071 91.02727  1.000 72.20821  ? 211 ASP A CA  1 
ATOM   1589 C C   . ASP A 1 227 ? -71.20644 -11.70896 89.81786  1.000 73.61295  ? 211 ASP A C   1 
ATOM   1590 O O   . ASP A 1 227 ? -71.36052 -12.15930 88.67871  1.000 73.09560  ? 211 ASP A O   1 
ATOM   1591 C CB  . ASP A 1 227 ? -69.69072 -13.07798 91.26862  1.000 73.50970  ? 211 ASP A CB  1 
ATOM   1592 C CG  . ASP A 1 227 ? -69.52982 -13.88179 92.54643  1.000 93.22833  ? 211 ASP A CG  1 
ATOM   1593 O OD1 . ASP A 1 227 ? -70.55588 -14.20765 93.17371  1.000 99.69712  ? 211 ASP A OD1 1 
ATOM   1594 O OD2 . ASP A 1 227 ? -68.37777 -14.17033 92.94003  1.000 91.84613  ? 211 ASP A OD2 1 
ATOM   1595 N N   . TYR A 1 228 ? -71.08694 -10.40779 90.07934  1.000 73.31858  ? 212 TYR A N   1 
ATOM   1596 C CA  . TYR A 1 228 ? -71.31163 -9.39457  89.05674  1.000 71.66675  ? 212 TYR A CA  1 
ATOM   1597 C C   . TYR A 1 228 ? -70.21839 -8.33582  89.12538  1.000 66.75197  ? 212 TYR A C   1 
ATOM   1598 O O   . TYR A 1 228 ? -69.73017 -7.99289  90.20640  1.000 70.50755  ? 212 TYR A O   1 
ATOM   1599 C CB  . TYR A 1 228 ? -72.70496 -8.76450  89.21350  1.000 67.39795  ? 212 TYR A CB  1 
ATOM   1600 C CG  . TYR A 1 228 ? -73.83273 -9.71635  88.86523  1.000 72.52846  ? 212 TYR A CG  1 
ATOM   1601 C CD1 . TYR A 1 228 ? -74.30788 -10.63382 89.79854  1.000 85.28408  ? 212 TYR A CD1 1 
ATOM   1602 C CD2 . TYR A 1 228 ? -74.42435 -9.69620  87.60832  1.000 79.42408  ? 212 TYR A CD2 1 
ATOM   1603 C CE1 . TYR A 1 228 ? -75.33526 -11.50941 89.48812  1.000 87.95912  ? 212 TYR A CE1 1 
ATOM   1604 C CE2 . TYR A 1 228 ? -75.45717 -10.56193 87.29177  1.000 89.11719  ? 212 TYR A CE2 1 
ATOM   1605 C CZ  . TYR A 1 228 ? -75.90584 -11.47027 88.23325  1.000 90.65715  ? 212 TYR A CZ  1 
ATOM   1606 O OH  . TYR A 1 228 ? -76.93011 -12.34050 87.92692  1.000 93.34435  ? 212 TYR A OH  1 
ATOM   1607 N N   . TYR A 1 229 ? -69.84438 -7.81955  87.95333  1.000 61.70355  ? 213 TYR A N   1 
ATOM   1608 C CA  . TYR A 1 229 ? -68.68940 -6.94680  87.80186  1.000 63.13778  ? 213 TYR A CA  1 
ATOM   1609 C C   . TYR A 1 229 ? -69.05306 -5.71416  86.98242  1.000 62.41036  ? 213 TYR A C   1 
ATOM   1610 O O   . TYR A 1 229 ? -70.05263 -5.69487  86.25890  1.000 64.28919  ? 213 TYR A O   1 
ATOM   1611 C CB  . TYR A 1 229 ? -67.52144 -7.67690  87.11819  1.000 64.19760  ? 213 TYR A CB  1 
ATOM   1612 C CG  . TYR A 1 229 ? -66.92106 -8.80097  87.93115  1.000 59.41511  ? 213 TYR A CG  1 
ATOM   1613 C CD1 . TYR A 1 229 ? -65.90006 -8.56006  88.84080  1.000 64.27729  ? 213 TYR A CD1 1 
ATOM   1614 C CD2 . TYR A 1 229 ? -67.35502 -10.10868 87.76721  1.000 64.68830  ? 213 TYR A CD2 1 
ATOM   1615 C CE1 . TYR A 1 229 ? -65.34326 -9.58795  89.58225  1.000 68.32694  ? 213 TYR A CE1 1 
ATOM   1616 C CE2 . TYR A 1 229 ? -66.80330 -11.14295 88.50116  1.000 68.80937  ? 213 TYR A CE2 1 
ATOM   1617 C CZ  . TYR A 1 229 ? -65.79934 -10.87898 89.40586  1.000 70.66402  ? 213 TYR A CZ  1 
ATOM   1618 O OH  . TYR A 1 229 ? -65.25644 -11.91571 90.13193  1.000 79.99014  ? 213 TYR A OH  1 
ATOM   1619 N N   . CYS A 1 230 ? -68.20552 -4.68361  87.09169  1.000 59.16541  ? 214 CYS A N   1 
ATOM   1620 C CA  . CYS A 1 230 ? -68.33641 -3.45107  86.32264  1.000 59.36919  ? 214 CYS A CA  1 
ATOM   1621 C C   . CYS A 1 230 ? -66.98219 -3.04792  85.74910  1.000 61.51880  ? 214 CYS A C   1 
ATOM   1622 O O   . CYS A 1 230 ? -65.93226 -3.36721  86.31534  1.000 61.84318  ? 214 CYS A O   1 
ATOM   1623 C CB  . CYS A 1 230 ? -68.88937 -2.29457  87.17725  1.000 66.10125  ? 214 CYS A CB  1 
ATOM   1624 S SG  . CYS A 1 230 ? -67.90005 -1.87768  88.64091  1.000 95.60244  ? 214 CYS A SG  1 
ATOM   1625 N N   . SER A 1 231 ? -67.01616 -2.33210  84.62169  1.000 62.73580  ? 215 SER A N   1 
ATOM   1626 C CA  . SER A 1 231 ? -65.80471 -1.82493  83.98608  1.000 61.16023  ? 215 SER A CA  1 
ATOM   1627 C C   . SER A 1 231 ? -66.10236 -0.49502  83.30178  1.000 59.59517  ? 215 SER A C   1 
ATOM   1628 O O   . SER A 1 231 ? -67.24217 -0.22264  82.91383  1.000 67.65543  ? 215 SER A O   1 
ATOM   1629 C CB  . SER A 1 231 ? -65.22519 -2.82606  82.97160  1.000 59.43169  ? 215 SER A CB  1 
ATOM   1630 O OG  . SER A 1 231 ? -65.99900 -2.89660  81.78490  1.000 51.72036  ? 215 SER A OG  1 
ATOM   1631 N N   . SER A 1 232 ? -65.06564 0.33056   83.15160  1.000 56.92194  ? 216 SER A N   1 
ATOM   1632 C CA  . SER A 1 232 ? -65.22079 1.63485   82.52332  1.000 63.64030  ? 216 SER A CA  1 
ATOM   1633 C C   . SER A 1 232 ? -63.92596 2.01949   81.82076  1.000 60.07717  ? 216 SER A C   1 
ATOM   1634 O O   . SER A 1 232 ? -62.84208 1.55448   82.18638  1.000 64.14052  ? 216 SER A O   1 
ATOM   1635 C CB  . SER A 1 232 ? -65.60026 2.70845   83.55602  1.000 73.14686  ? 216 SER A CB  1 
ATOM   1636 O OG  . SER A 1 232 ? -65.68107 4.00594   82.98301  1.000 70.26549  ? 216 SER A OG  1 
ATOM   1637 N N   . TYR A 1 233 ? -64.05045 2.85976   80.79428  1.000 55.76104  ? 217 TYR A N   1 
ATOM   1638 C CA  . TYR A 1 233 ? -62.89080 3.58720   80.30786  1.000 54.33353  ? 217 TYR A CA  1 
ATOM   1639 C C   . TYR A 1 233 ? -62.34059 4.44702   81.44591  1.000 65.34820  ? 217 TYR A C   1 
ATOM   1640 O O   . TYR A 1 233 ? -63.06143 4.82293   82.37685  1.000 74.54766  ? 217 TYR A O   1 
ATOM   1641 C CB  . TYR A 1 233 ? -63.25979 4.45527   79.10433  1.000 56.22268  ? 217 TYR A CB  1 
ATOM   1642 C CG  . TYR A 1 233 ? -62.05977 5.01155   78.39374  1.000 54.26486  ? 217 TYR A CG  1 
ATOM   1643 C CD1 . TYR A 1 233 ? -61.30820 4.21150   77.54570  1.000 62.88672  ? 217 TYR A CD1 1 
ATOM   1644 C CD2 . TYR A 1 233 ? -61.65820 6.32366   78.58815  1.000 57.35026  ? 217 TYR A CD2 1 
ATOM   1645 C CE1 . TYR A 1 233 ? -60.19792 4.70074   76.89817  1.000 62.75089  ? 217 TYR A CE1 1 
ATOM   1646 C CE2 . TYR A 1 233 ? -60.54227 6.82682   77.94303  1.000 65.70552  ? 217 TYR A CE2 1 
ATOM   1647 C CZ  . TYR A 1 233 ? -59.81646 6.00611   77.09781  1.000 64.88394  ? 217 TYR A CZ  1 
ATOM   1648 O OH  . TYR A 1 233 ? -58.70415 6.47393   76.43759  1.000 62.34504  ? 217 TYR A OH  1 
ATOM   1649 N N   . THR A 1 234 ? -61.04385 4.75998   81.37336  1.000 60.10587  ? 218 THR A N   1 
ATOM   1650 C CA  . THR A 1 234 ? -60.33918 5.30099   82.52911  1.000 67.47138  ? 218 THR A CA  1 
ATOM   1651 C C   . THR A 1 234 ? -59.74950 6.69334   82.33745  1.000 76.61632  ? 218 THR A C   1 
ATOM   1652 O O   . THR A 1 234 ? -59.17768 7.22737   83.29705  1.000 93.78512  ? 218 THR A O   1 
ATOM   1653 C CB  . THR A 1 234 ? -59.20435 4.35463   82.93943  1.000 59.37921  ? 218 THR A CB  1 
ATOM   1654 O OG1 . THR A 1 234 ? -58.65039 4.77340   84.18989  1.000 83.09830  ? 218 THR A OG1 1 
ATOM   1655 C CG2 . THR A 1 234 ? -58.13184 4.45362   81.92337  1.000 52.74455  ? 218 THR A CG2 1 
ATOM   1656 N N   . SER A 1 235 ? -59.83681 7.27565   81.13530  1.000 66.41083  ? 219 SER A N   1 
ATOM   1657 C CA  . SER A 1 235 ? -59.21766 8.55899   80.79247  1.000 66.07637  ? 219 SER A CA  1 
ATOM   1658 C C   . SER A 1 235 ? -57.70583 8.41570   80.64416  1.000 65.28006  ? 219 SER A C   1 
ATOM   1659 O O   . SER A 1 235 ? -57.04979 9.27390   80.04375  1.000 74.68562  ? 219 SER A O   1 
ATOM   1660 C CB  . SER A 1 235 ? -59.55415 9.64427   81.82844  1.000 65.99835  ? 219 SER A CB  1 
ATOM   1661 O OG  . SER A 1 235 ? -59.10593 10.92604  81.42573  1.000 70.58278  ? 219 SER A OG  1 
ATOM   1662 N N   . LYS A 1 236 ? -57.14519 7.33404   81.18057  1.000 54.91765  ? 220 LYS A N   1 
ATOM   1663 C CA  . LYS A 1 236 ? -55.73758 7.01120   81.00954  1.000 53.91687  ? 220 LYS A CA  1 
ATOM   1664 C C   . LYS A 1 236 ? -55.50019 6.02518   79.87399  1.000 61.48223  ? 220 LYS A C   1 
ATOM   1665 O O   . LYS A 1 236 ? -54.41113 5.44905   79.79151  1.000 61.91006  ? 220 LYS A O   1 
ATOM   1666 C CB  . LYS A 1 236 ? -55.15706 6.43908   82.30345  1.000 56.99916  ? 220 LYS A CB  1 
ATOM   1667 C CG  . LYS A 1 236 ? -55.30626 7.29778   83.54778  1.000 66.22385  ? 220 LYS A CG  1 
ATOM   1668 C CD  . LYS A 1 236 ? -54.77396 6.52112   84.75649  1.000 85.03136  ? 220 LYS A CD  1 
ATOM   1669 C CE  . LYS A 1 236 ? -54.93947 7.27281   86.07081  1.000 102.08524 ? 220 LYS A CE  1 
ATOM   1670 N NZ  . LYS A 1 236 ? -54.26483 8.59889   86.04137  1.000 108.38384 ? 220 LYS A NZ  1 
ATOM   1671 N N   . ASN A 1 237 ? -56.49689 5.81107   79.01030  1.000 67.20749  ? 221 ASN A N   1 
ATOM   1672 C CA  . ASN A 1 237 ? -56.41373 4.87247   77.88977  1.000 65.45869  ? 221 ASN A CA  1 
ATOM   1673 C C   . ASN A 1 237 ? -56.33855 3.41993   78.34594  1.000 66.56637  ? 221 ASN A C   1 
ATOM   1674 O O   . ASN A 1 237 ? -55.76759 2.57969   77.65192  1.000 83.76508  ? 221 ASN A O   1 
ATOM   1675 C CB  . ASN A 1 237 ? -55.22911 5.18728   76.97479  1.000 68.56638  ? 221 ASN A CB  1 
ATOM   1676 C CG  . ASN A 1 237 ? -55.59171 6.13918   75.87623  1.000 72.02386  ? 221 ASN A CG  1 
ATOM   1677 O OD1 . ASN A 1 237 ? -55.37118 7.34451   75.98309  1.000 84.01019  ? 221 ASN A OD1 1 
ATOM   1678 N ND2 . ASN A 1 237 ? -56.15898 5.60688   74.80534  1.000 70.90352  ? 221 ASN A ND2 1 
ATOM   1679 N N   . THR A 1 238 A -56.90191 3.10795   79.51224  1.000 57.33029  ? 221 THR A N   1 
ATOM   1680 C CA  . THR A 1 238 A -56.92804 1.73596   80.00873  1.000 50.71976  ? 221 THR A CA  1 
ATOM   1681 C C   . THR A 1 238 A -58.33597 1.31334   80.41491  1.000 57.64439  ? 221 THR A C   1 
ATOM   1682 O O   . THR A 1 238 A -59.30410 2.04820   80.19259  1.000 68.91401  ? 221 THR A O   1 
ATOM   1683 C CB  . THR A 1 238 A -55.99118 1.56572   81.20806  1.000 52.61681  ? 221 THR A CB  1 
ATOM   1684 O OG1 . THR A 1 238 A -56.70556 1.85726   82.41491  1.000 56.62924  ? 221 THR A OG1 1 
ATOM   1685 C CG2 . THR A 1 238 A -54.80618 2.50048   81.10518  1.000 59.98247  ? 221 THR A CG2 1 
ATOM   1686 N N   . LEU A 1 239 ? -58.45340 0.13362   81.02924  1.000 58.15944  ? 222 LEU A N   1 
ATOM   1687 C CA  . LEU A 1 239 ? -59.73081 -0.40238  81.48327  1.000 55.11266  ? 222 LEU A CA  1 
ATOM   1688 C C   . LEU A 1 239 ? -59.62455 -0.79676  82.95177  1.000 56.95457  ? 222 LEU A C   1 
ATOM   1689 O O   . LEU A 1 239 ? -58.63298 -1.40201  83.37109  1.000 58.27580  ? 222 LEU A O   1 
ATOM   1690 C CB  . LEU A 1 239 ? -60.14682 -1.61163  80.63973  1.000 50.64885  ? 222 LEU A CB  1 
ATOM   1691 C CG  . LEU A 1 239 ? -60.79954 -1.30583  79.28894  1.000 51.51890  ? 222 LEU A CG  1 
ATOM   1692 C CD1 . LEU A 1 239 ? -60.81486 -2.54011  78.40693  1.000 50.55118  ? 222 LEU A CD1 1 
ATOM   1693 C CD2 . LEU A 1 239 ? -62.20929 -0.76320  79.46917  1.000 65.31421  ? 222 LEU A CD2 1 
ATOM   1694 N N   . ILE A 1 240 ? -60.64561 -0.46275  83.73479  1.000 54.40702  ? 223 ILE A N   1 
ATOM   1695 C CA  . ILE A 1 240 ? -60.63377 -0.71815  85.16934  1.000 54.55670  ? 223 ILE A CA  1 
ATOM   1696 C C   . ILE A 1 240 ? -61.78896 -1.64728  85.50809  1.000 57.60868  ? 223 ILE A C   1 
ATOM   1697 O O   . ILE A 1 240 ? -62.91132 -1.45145  85.03198  1.000 55.44342  ? 223 ILE A O   1 
ATOM   1698 C CB  . ILE A 1 240 ? -60.72149 0.59112   85.97789  1.000 55.34128  ? 223 ILE A CB  1 
ATOM   1699 C CG1 . ILE A 1 240 ? -59.50713 1.47367   85.68506  1.000 72.13011  ? 223 ILE A CG1 1 
ATOM   1700 C CG2 . ILE A 1 240 ? -60.78792 0.29527   87.45291  1.000 64.88229  ? 223 ILE A CG2 1 
ATOM   1701 C CD1 . ILE A 1 240 ? -58.18488 0.92237   86.22137  1.000 82.80527  ? 223 ILE A CD1 1 
ATOM   1702 N N   . PHE A 1 241 ? -61.51045 -2.65879  86.32861  1.000 62.00229  ? 224 PHE A N   1 
ATOM   1703 C CA  . PHE A 1 241 ? -62.49440 -3.65634  86.72553  1.000 56.19558  ? 224 PHE A CA  1 
ATOM   1704 C C   . PHE A 1 241 ? -62.71370 -3.59110  88.23075  1.000 60.55926  ? 224 PHE A C   1 
ATOM   1705 O O   . PHE A 1 241 ? -61.76365 -3.39805  88.99597  1.000 72.17747  ? 224 PHE A O   1 
ATOM   1706 C CB  . PHE A 1 241 ? -62.03978 -5.05437  86.31271  1.000 58.64309  ? 224 PHE A CB  1 
ATOM   1707 C CG  . PHE A 1 241 ? -62.73412 -5.57277  85.09426  1.000 56.48243  ? 224 PHE A CG  1 
ATOM   1708 C CD1 . PHE A 1 241 ? -62.28148 -5.22830  83.83283  1.000 59.69141  ? 224 PHE A CD1 1 
ATOM   1709 C CD2 . PHE A 1 241 ? -63.82505 -6.41353  85.20367  1.000 58.34283  ? 224 PHE A CD2 1 
ATOM   1710 C CE1 . PHE A 1 241 ? -62.91136 -5.69648  82.69880  1.000 62.71788  ? 224 PHE A CE1 1 
ATOM   1711 C CE2 . PHE A 1 241 ? -64.45831 -6.88998  84.07312  1.000 64.56949  ? 224 PHE A CE2 1 
ATOM   1712 C CZ  . PHE A 1 241 ? -63.99961 -6.52932  82.81804  1.000 70.42439  ? 224 PHE A CZ  1 
ATOM   1713 N N   . GLY A 1 242 ? -63.96708 -3.75438  88.64908  1.000 56.86590  ? 225 GLY A N   1 
ATOM   1714 C CA  . GLY A 1 242 ? -64.33523 -3.64119  90.04395  1.000 65.35559  ? 225 GLY A CA  1 
ATOM   1715 C C   . GLY A 1 242 ? -64.00132 -4.88082  90.85701  1.000 74.77883  ? 225 GLY A C   1 
ATOM   1716 O O   . GLY A 1 242 ? -63.30311 -5.79567  90.41642  1.000 78.36217  ? 225 GLY A O   1 
ATOM   1717 N N   . GLY A 1 243 ? -64.52268 -4.89631  92.08376  1.000 72.73788  ? 226 GLY A N   1 
ATOM   1718 C CA  . GLY A 1 243 ? -64.29875 -6.00001  92.99841  1.000 68.62390  ? 226 GLY A CA  1 
ATOM   1719 C C   . GLY A 1 243 ? -65.08382 -7.24919  92.65259  1.000 70.33325  ? 226 GLY A C   1 
ATOM   1720 O O   . GLY A 1 243 ? -64.50181 -8.31058  92.41341  1.000 79.33196  ? 226 GLY A O   1 
ATOM   1721 N N   . GLY A 1 244 ? -66.40807 -7.13590  92.61567  1.000 66.12416  ? 227 GLY A N   1 
ATOM   1722 C CA  . GLY A 1 244 ? -67.25711 -8.28623  92.36883  1.000 72.95510  ? 227 GLY A CA  1 
ATOM   1723 C C   . GLY A 1 244 ? -68.15224 -8.58146  93.55477  1.000 75.38017  ? 227 GLY A C   1 
ATOM   1724 O O   . GLY A 1 244 ? -67.66571 -8.77732  94.67310  1.000 83.46013  ? 227 GLY A O   1 
ATOM   1725 N N   . THR A 1 245 ? -69.46237 -8.62732  93.32591  1.000 69.25116  ? 228 THR A N   1 
ATOM   1726 C CA  . THR A 1 245 ? -70.44073 -8.73605  94.39867  1.000 75.42143  ? 228 THR A CA  1 
ATOM   1727 C C   . THR A 1 245 ? -71.17507 -10.07285 94.34253  1.000 80.84514  ? 228 THR A C   1 
ATOM   1728 O O   . THR A 1 245 ? -71.56907 -10.53335 93.26627  1.000 71.15693  ? 228 THR A O   1 
ATOM   1729 C CB  . THR A 1 245 ? -71.44707 -7.58918  94.32741  1.000 72.65720  ? 228 THR A CB  1 
ATOM   1730 O OG1 . THR A 1 245 ? -70.79473 -6.40367  93.85149  1.000 56.98342  ? 228 THR A OG1 1 
ATOM   1731 C CG2 . THR A 1 245 ? -72.02305 -7.32196  95.71057  1.000 89.95797  ? 228 THR A CG2 1 
ATOM   1732 N N   . LYS A 1 246 ? -71.38037 -10.67740 95.51634  1.000 83.59836  ? 229 LYS A N   1 
ATOM   1733 C CA  . LYS A 1 246 ? -71.99358 -11.99827 95.64897  1.000 84.51506  ? 229 LYS A CA  1 
ATOM   1734 C C   . LYS A 1 246 ? -73.47541 -11.83612 95.97329  1.000 88.98945  ? 229 LYS A C   1 
ATOM   1735 O O   . LYS A 1 246 ? -73.83593 -11.50773 97.10829  1.000 99.25979  ? 229 LYS A O   1 
ATOM   1736 C CB  . LYS A 1 246 ? -71.28429 -12.80511 96.73709  1.000 89.73286  ? 229 LYS A CB  1 
ATOM   1737 C CG  . LYS A 1 246 ? -71.74305 -14.25742 96.91511  1.000 98.58552  ? 229 LYS A CG  1 
ATOM   1738 C CD  . LYS A 1 246 ? -70.81742 -15.23925 96.20559  1.000 94.54824  ? 229 LYS A CD  1 
ATOM   1739 C CE  . LYS A 1 246 ? -71.47252 -16.60401 96.02653  1.000 100.09125 ? 229 LYS A CE  1 
ATOM   1740 N NZ  . LYS A 1 246 ? -72.56175 -16.57044 95.01193  1.000 89.31932  ? 229 LYS A NZ  1 
ATOM   1741 N N   . LEU A 1 247 ? -74.33012 -12.07769 94.98204  1.000 75.23440  ? 230 LEU A N   1 
ATOM   1742 C CA  . LEU A 1 247 ? -75.76977 -12.03187 95.19323  1.000 83.06062  ? 230 LEU A CA  1 
ATOM   1743 C C   . LEU A 1 247 ? -76.24864 -13.35736 95.77277  1.000 95.81763  ? 230 LEU A C   1 
ATOM   1744 O O   . LEU A 1 247 ? -75.91672 -14.42399 95.25062  1.000 95.89349  ? 230 LEU A O   1 
ATOM   1745 C CB  . LEU A 1 247 ? -76.48910 -11.73506 93.87844  1.000 82.12923  ? 230 LEU A CB  1 
ATOM   1746 C CG  . LEU A 1 247 ? -78.01744 -11.65743 93.93613  1.000 88.36196  ? 230 LEU A CG  1 
ATOM   1747 C CD1 . LEU A 1 247 ? -78.48393 -10.77025 95.08870  1.000 96.75266  ? 230 LEU A CD1 1 
ATOM   1748 C CD2 . LEU A 1 247 ? -78.58689 -11.17533 92.61219  1.000 76.84294  ? 230 LEU A CD2 1 
ATOM   1749 N N   . THR A 1 248 ? -77.01926 -13.28957 96.85762  1.000 97.30987  ? 231 THR A N   1 
ATOM   1750 C CA  . THR A 1 248 ? -77.56582 -14.46907 97.52033  1.000 95.87137  ? 231 THR A CA  1 
ATOM   1751 C C   . THR A 1 248 ? -79.08448 -14.39407 97.46820  1.000 98.35131  ? 231 THR A C   1 
ATOM   1752 O O   . THR A 1 248 ? -79.67527 -13.41138 97.92805  1.000 98.21098  ? 231 THR A O   1 
ATOM   1753 C CB  . THR A 1 248 ? -77.08445 -14.57270 98.97249  1.000 100.49921 ? 231 THR A CB  1 
ATOM   1754 O OG1 . THR A 1 248 ? -75.65156 -14.57109 99.01066  1.000 96.39863  ? 231 THR A OG1 1 
ATOM   1755 C CG2 . THR A 1 248 ? -77.60243 -15.85399 99.61752  1.000 109.96021 ? 231 THR A CG2 1 
ATOM   1756 N N   . VAL A 1 249 ? -79.70876 -15.42766 96.91033  1.000 103.87269 ? 232 VAL A N   1 
ATOM   1757 C CA  . VAL A 1 249 ? -81.16138 -15.53274 96.83600  1.000 103.70491 ? 232 VAL A CA  1 
ATOM   1758 C C   . VAL A 1 249 ? -81.66139 -16.33919 98.02871  1.000 109.26646 ? 232 VAL A C   1 
ATOM   1759 O O   . VAL A 1 249 ? -80.96912 -17.22506 98.54418  1.000 113.50343 ? 232 VAL A O   1 
ATOM   1760 C CB  . VAL A 1 249 ? -81.59432 -16.16133 95.49421  1.000 96.90786  ? 232 VAL A CB  1 
ATOM   1761 C CG1 . VAL A 1 249 ? -83.09266 -16.04256 95.30356  1.000 95.77275  ? 232 VAL A CG1 1 
ATOM   1762 C CG2 . VAL A 1 249 ? -80.86876 -15.49790 94.34636  1.000 96.85493  ? 232 VAL A CG2 1 
ATOM   1763 N N   . LEU A 1 250 ? -82.87691 -16.03036 98.47499  1.000 103.11938 ? 233 LEU A N   1 
ATOM   1764 C CA  . LEU A 1 250 ? -83.41587 -16.61259 99.69993  1.000 104.30865 ? 233 LEU A CA  1 
ATOM   1765 C C   . LEU A 1 250 ? -84.76023 -17.30493 99.45820  1.000 95.95193  ? 233 LEU A C   1 
ATOM   1766 O O   . LEU A 1 250 ? -85.20130 -18.13887 100.25488 1.000 84.08506  ? 233 LEU A O   1 
ATOM   1767 C CB  . LEU A 1 250 ? -83.56022 -15.52687 100.76783 1.000 99.72743  ? 233 LEU A CB  1 
ATOM   1768 C CG  . LEU A 1 250 ? -82.24684 -14.82543 101.12738 1.000 83.05444  ? 233 LEU A CG  1 
ATOM   1769 C CD1 . LEU A 1 250 ? -82.52082 -13.61175 101.98351 1.000 78.45559  ? 233 LEU A CD1 1 
ATOM   1770 C CD2 . LEU A 1 250 ? -81.27658 -15.77060 101.82118 1.000 82.92119  ? 233 LEU A CD2 1 
ATOM   1771 N N   . GLN B 2 30  ? -16.63485 17.27485  30.46245  1.000 126.42141 ? 26  GLN F N   1 
ATOM   1772 C CA  . GLN B 2 30  ? -15.62440 18.30379  30.71197  1.000 138.79849 ? 26  GLN F CA  1 
ATOM   1773 C C   . GLN B 2 30  ? -16.03393 19.75592  30.47363  1.000 144.67883 ? 26  GLN F C   1 
ATOM   1774 O O   . GLN B 2 30  ? -16.93647 20.29568  31.11242  1.000 142.46257 ? 26  GLN F O   1 
ATOM   1775 C CB  . GLN B 2 30  ? -14.36986 18.03932  29.85682  1.000 138.06642 ? 26  GLN F CB  1 
ATOM   1776 C CG  . GLN B 2 30  ? -13.55475 16.81729  30.22273  1.000 133.22152 ? 26  GLN F CG  1 
ATOM   1777 C CD  . GLN B 2 30  ? -12.71788 17.05899  31.47647  1.000 135.42671 ? 26  GLN F CD  1 
ATOM   1778 O OE1 . GLN B 2 30  ? -12.45095 18.20519  31.84728  1.000 136.56821 ? 26  GLN F OE1 1 
ATOM   1779 N NE2 . GLN B 2 30  ? -12.28696 15.98112  32.12143  1.000 135.14520 ? 26  GLN F NE2 1 
ATOM   1780 N N   . ASN B 2 31  ? -15.32314 20.34781  29.51965  1.000 148.63695 ? 27  ASN F N   1 
ATOM   1781 C CA  . ASN B 2 31  ? -15.47085 21.73755  29.11001  1.000 146.51459 ? 27  ASN F CA  1 
ATOM   1782 C C   . ASN B 2 31  ? -16.46048 21.89303  27.95659  1.000 138.88196 ? 27  ASN F C   1 
ATOM   1783 O O   . ASN B 2 31  ? -16.28864 21.29414  26.88930  1.000 137.54549 ? 27  ASN F O   1 
ATOM   1784 C CB  . ASN B 2 31  ? -14.10123 22.31531  28.76249  1.000 143.37650 ? 27  ASN F CB  1 
ATOM   1785 C CG  . ASN B 2 31  ? -13.23121 22.51525  30.00033  1.000 142.35180 ? 27  ASN F CG  1 
ATOM   1786 O OD1 . ASN B 2 31  ? -13.72085 22.47507  31.13291  1.000 144.62696 ? 27  ASN F OD1 1 
ATOM   1787 N ND2 . ASN B 2 31  ? -11.93861 22.72547  29.78866  1.000 138.48317 ? 27  ASN F ND2 1 
ATOM   1788 N N   . ILE B 2 32  ? -17.48740 22.70524  28.18590  1.000 130.96112 ? 28  ILE F N   1 
ATOM   1789 C CA  . ILE B 2 32  ? -18.51843 23.02123  27.19918  1.000 132.83262 ? 28  ILE F CA  1 
ATOM   1790 C C   . ILE B 2 32  ? -17.97400 24.08098  26.24455  1.000 136.19027 ? 28  ILE F C   1 
ATOM   1791 O O   . ILE B 2 32  ? -17.43219 25.11094  26.66532  1.000 133.45317 ? 28  ILE F O   1 
ATOM   1792 C CB  . ILE B 2 32  ? -19.83599 23.44033  27.88030  1.000 131.38065 ? 28  ILE F CB  1 
ATOM   1793 C CG1 . ILE B 2 32  ? -19.79934 24.86601  28.43221  1.000 129.77587 ? 28  ILE F CG1 1 
ATOM   1794 C CG2 . ILE B 2 32  ? -20.21556 22.44214  28.97303  1.000 136.70149 ? 28  ILE F CG2 1 
ATOM   1795 C CD1 . ILE B 2 32  ? -21.10448 25.27801  29.08846  1.000 133.39470 ? 28  ILE F CD1 1 
ATOM   1796 N N   . THR B 2 33  ? -18.08354 23.79262  24.94572  1.000 141.56471 ? 29  THR F N   1 
ATOM   1797 C CA  . THR B 2 33  ? -17.61279 24.60412  23.82914  1.000 133.66826 ? 29  THR F CA  1 
ATOM   1798 C C   . THR B 2 33  ? -18.74892 24.85719  22.84225  1.000 123.91033 ? 29  THR F C   1 
ATOM   1799 O O   . THR B 2 33  ? -19.80906 24.22424  22.88726  1.000 123.55884 ? 29  THR F O   1 
ATOM   1800 C CB  . THR B 2 33  ? -16.43942 23.91914  23.10034  1.000 130.50915 ? 29  THR F CB  1 
ATOM   1801 O OG1 . THR B 2 33  ? -16.84148 22.61663  22.65576  1.000 126.64596 ? 29  THR F OG1 1 
ATOM   1802 C CG2 . THR B 2 33  ? -15.24120 23.76599  24.02454  1.000 124.54018 ? 29  THR F CG2 1 
ATOM   1803 N N   . GLU B 2 34  ? -18.49824 25.79966  21.93273  1.000 116.02974 ? 30  GLU F N   1 
ATOM   1804 C CA  . GLU B 2 34  ? -19.45349 26.23748  20.92386  1.000 128.21573 ? 30  GLU F CA  1 
ATOM   1805 C C   . GLU B 2 34  ? -18.80522 26.35038  19.55831  1.000 144.17357 ? 30  GLU F C   1 
ATOM   1806 O O   . GLU B 2 34  ? -17.60017 26.56903  19.42825  1.000 150.50462 ? 30  GLU F O   1 
ATOM   1807 C CB  . GLU B 2 34  ? -19.98939 27.65285  21.24704  1.000 123.07738 ? 30  GLU F CB  1 
ATOM   1808 C CG  . GLU B 2 34  ? -21.14457 27.78928  22.19349  1.000 122.50089 ? 30  GLU F CG  1 
ATOM   1809 C CD  . GLU B 2 34  ? -22.47697 27.72716  21.49090  1.000 130.76959 ? 30  GLU F CD  1 
ATOM   1810 O OE1 . GLU B 2 34  ? -22.53716 27.17948  20.37826  1.000 142.06384 ? 30  GLU F OE1 1 
ATOM   1811 O OE2 . GLU B 2 34  ? -23.46578 28.24143  22.05075  1.000 127.71762 ? 30  GLU F OE2 1 
ATOM   1812 N N   . GLU B 2 35  ? -19.64857 26.18710  18.54150  1.000 144.65221 ? 31  GLU F N   1 
ATOM   1813 C CA  . GLU B 2 35  ? -19.27418 26.30778  17.13884  1.000 141.38700 ? 31  GLU F CA  1 
ATOM   1814 C C   . GLU B 2 35  ? -20.43110 27.01672  16.45927  1.000 138.72266 ? 31  GLU F C   1 
ATOM   1815 O O   . GLU B 2 35  ? -21.53182 26.46481  16.37681  1.000 142.16333 ? 31  GLU F O   1 
ATOM   1816 C CB  . GLU B 2 35  ? -19.02072 24.94330  16.49436  1.000 138.28261 ? 31  GLU F CB  1 
ATOM   1817 C CG  . GLU B 2 35  ? -17.72997 24.26905  16.90472  1.000 143.76940 ? 31  GLU F CG  1 
ATOM   1818 C CD  . GLU B 2 35  ? -17.59453 22.87248  16.32995  1.000 154.13300 ? 31  GLU F CD  1 
ATOM   1819 O OE1 . GLU B 2 35  ? -18.36670 22.52497  15.40927  1.000 145.44897 ? 31  GLU F OE1 1 
ATOM   1820 O OE2 . GLU B 2 35  ? -16.71237 22.12331  16.80128  1.000 166.36082 ? 31  GLU F OE2 1 
ATOM   1821 N N   . PHE B 2 36  ? -20.18568 28.22246  15.97165  1.000 137.72097 ? 32  PHE F N   1 
ATOM   1822 C CA  . PHE B 2 36  ? -21.17740 28.96897  15.21462  1.000 145.16614 ? 32  PHE F CA  1 
ATOM   1823 C C   . PHE B 2 36  ? -20.93764 28.75024  13.73105  1.000 155.66978 ? 32  PHE F C   1 
ATOM   1824 O O   . PHE B 2 36  ? -19.80483 28.88157  13.25531  1.000 160.88251 ? 32  PHE F O   1 
ATOM   1825 C CB  . PHE B 2 36  ? -21.11951 30.46107  15.53804  1.000 133.89724 ? 32  PHE F CB  1 
ATOM   1826 C CG  . PHE B 2 36  ? -21.97740 31.30663  14.63819  1.000 135.05981 ? 32  PHE F CG  1 
ATOM   1827 C CD1 . PHE B 2 36  ? -23.34883 31.36962  14.81542  1.000 137.21019 ? 32  PHE F CD1 1 
ATOM   1828 C CD2 . PHE B 2 36  ? -21.40730 32.03620  13.60550  1.000 135.92321 ? 32  PHE F CD2 1 
ATOM   1829 C CE1 . PHE B 2 36  ? -24.13497 32.14983  13.98121  1.000 132.02216 ? 32  PHE F CE1 1 
ATOM   1830 C CE2 . PHE B 2 36  ? -22.18896 32.81609  12.77184  1.000 130.46950 ? 32  PHE F CE2 1 
ATOM   1831 C CZ  . PHE B 2 36  ? -23.55261 32.87212  12.96022  1.000 126.01435 ? 32  PHE F CZ  1 
ATOM   1832 N N   . TYR B 2 37  ? -21.99892 28.41683  13.00793  1.000 148.36334 ? 33  TYR F N   1 
ATOM   1833 C CA  . TYR B 2 37  ? -21.91711 28.14931  11.57743  1.000 145.91243 ? 33  TYR F CA  1 
ATOM   1834 C C   . TYR B 2 37  ? -22.51836 29.32989  10.82330  1.000 146.36319 ? 33  TYR F C   1 
ATOM   1835 O O   . TYR B 2 37  ? -23.74038 29.50280  10.76719  1.000 147.65531 ? 33  TYR F O   1 
ATOM   1836 C CB  . TYR B 2 37  ? -22.58101 26.81980  11.23864  1.000 141.20024 ? 33  TYR F CB  1 
ATOM   1837 C CG  . TYR B 2 37  ? -21.99805 25.68642  12.05135  1.000 137.03948 ? 33  TYR F CG  1 
ATOM   1838 C CD1 . TYR B 2 37  ? -20.79599 25.10020  11.67875  1.000 145.63716 ? 33  TYR F CD1 1 
ATOM   1839 C CD2 . TYR B 2 37  ? -22.64040 25.19965  13.17933  1.000 129.79674 ? 33  TYR F CD2 1 
ATOM   1840 C CE1 . TYR B 2 37  ? -20.24334 24.06955  12.40957  1.000 146.88997 ? 33  TYR F CE1 1 
ATOM   1841 C CE2 . TYR B 2 37  ? -22.09410 24.16141  13.91656  1.000 133.13059 ? 33  TYR F CE2 1 
ATOM   1842 C CZ  . TYR B 2 37  ? -20.89695 23.59942  13.52497  1.000 137.19589 ? 33  TYR F CZ  1 
ATOM   1843 O OH  . TYR B 2 37  ? -20.34429 22.56857  14.25102  1.000 134.06060 ? 33  TYR F OH  1 
ATOM   1844 N N   . GLN B 2 38  ? -21.62273 30.13793  10.25247  1.000 141.44894 ? 34  GLN F N   1 
ATOM   1845 C CA  . GLN B 2 38  ? -21.99954 31.30709  9.46978   1.000 139.46193 ? 34  GLN F CA  1 
ATOM   1846 C C   . GLN B 2 38  ? -22.82155 30.91001  8.25032   1.000 143.80853 ? 34  GLN F C   1 
ATOM   1847 O O   . GLN B 2 38  ? -23.64590 31.69713  7.76759   1.000 137.02194 ? 34  GLN F O   1 
ATOM   1848 C CB  . GLN B 2 38  ? -20.73016 32.05788  9.07003   1.000 141.39852 ? 34  GLN F CB  1 
ATOM   1849 C CG  . GLN B 2 38  ? -20.91730 33.27683  8.20029   1.000 144.46028 ? 34  GLN F CG  1 
ATOM   1850 C CD  . GLN B 2 38  ? -19.58474 33.86655  7.77407   1.000 141.08466 ? 34  GLN F CD  1 
ATOM   1851 O OE1 . GLN B 2 38  ? -18.52130 33.35223  8.12958   1.000 133.34168 ? 34  GLN F OE1 1 
ATOM   1852 N NE2 . GLN B 2 38  ? -19.63509 34.93737  6.99354   1.000 139.12823 ? 34  GLN F NE2 1 
ATOM   1853 N N   . SER B 2 39  ? -22.62250 29.68308  7.75864   1.000 147.95590 ? 35  SER F N   1 
ATOM   1854 C CA  . SER B 2 39  ? -23.29948 29.21444  6.55566   1.000 147.40242 ? 35  SER F CA  1 
ATOM   1855 C C   . SER B 2 39  ? -24.78867 29.00200  6.79673   1.000 149.06676 ? 35  SER F C   1 
ATOM   1856 O O   . SER B 2 39  ? -25.59871 29.21618  5.88825   1.000 148.29984 ? 35  SER F O   1 
ATOM   1857 C CB  . SER B 2 39  ? -22.64448 27.92026  6.05934   1.000 131.20322 ? 35  SER F CB  1 
ATOM   1858 O OG  . SER B 2 39  ? -22.72343 26.88074  7.02454   1.000 116.21523 ? 35  SER F OG  1 
ATOM   1859 N N   . THR B 2 40  ? -25.17518 28.62212  8.01068   1.000 149.66789 ? 36  THR F N   1 
ATOM   1860 C CA  . THR B 2 40  ? -26.56454 28.30701  8.29644   1.000 148.62825 ? 36  THR F CA  1 
ATOM   1861 C C   . THR B 2 40  ? -27.20081 29.22471  9.32900   1.000 148.74042 ? 36  THR F C   1 
ATOM   1862 O O   . THR B 2 40  ? -28.36375 29.00355  9.68214   1.000 150.05184 ? 36  THR F O   1 
ATOM   1863 C CB  . THR B 2 40  ? -26.69362 26.85828  8.78262   1.000 148.85674 ? 36  THR F CB  1 
ATOM   1864 O OG1 . THR B 2 40  ? -25.81744 26.64760  9.89601   1.000 137.28281 ? 36  THR F OG1 1 
ATOM   1865 C CG2 . THR B 2 40  ? -26.30260 25.90191  7.67099   1.000 154.06473 ? 36  THR F CG2 1 
ATOM   1866 N N   . CYS B 2 41  ? -26.48135 30.23689  9.82625   1.000 148.59385 ? 37  CYS F N   1 
ATOM   1867 C CA  . CYS B 2 41  ? -27.02164 31.16936  10.81644  1.000 142.51312 ? 37  CYS F CA  1 
ATOM   1868 C C   . CYS B 2 41  ? -27.53997 30.39940  12.02817  1.000 135.50204 ? 37  CYS F C   1 
ATOM   1869 O O   . CYS B 2 41  ? -28.65210 30.61090  12.50659  1.000 124.92944 ? 37  CYS F O   1 
ATOM   1870 C CB  . CYS B 2 41  ? -28.10926 32.05639  10.20600  1.000 140.87464 ? 37  CYS F CB  1 
ATOM   1871 S SG  . CYS B 2 41  ? -28.63472 33.47703  11.20491  1.000 123.07464 ? 37  CYS F SG  1 
ATOM   1872 N N   . SER B 2 42  ? -26.69467 29.50074  12.52509  1.000 143.43694 ? 38  SER F N   1 
ATOM   1873 C CA  . SER B 2 42  ? -27.00176 28.60622  13.62685  1.000 146.63639 ? 38  SER F CA  1 
ATOM   1874 C C   . SER B 2 42  ? -25.76914 28.41724  14.49626  1.000 147.81747 ? 38  SER F C   1 
ATOM   1875 O O   . SER B 2 42  ? -24.63952 28.56233  14.03452  1.000 147.79657 ? 38  SER F O   1 
ATOM   1876 C CB  . SER B 2 42  ? -27.51508 27.24432  13.10567  1.000 147.54071 ? 38  SER F CB  1 
ATOM   1877 O OG  . SER B 2 42  ? -26.55142 26.59138  12.28856  1.000 144.05182 ? 38  SER F OG  1 
ATOM   1878 N N   . ALA B 2 43  ? -26.00607 28.06763  15.76383  1.000 142.12890 ? 39  ALA F N   1 
ATOM   1879 C CA  . ALA B 2 43  ? -24.93529 27.82326  16.71849  1.000 129.05909 ? 39  ALA F CA  1 
ATOM   1880 C C   . ALA B 2 43  ? -25.24872 26.51287  17.41481  1.000 121.75834 ? 39  ALA F C   1 
ATOM   1881 O O   . ALA B 2 43  ? -26.41454 26.19289  17.65241  1.000 124.35973 ? 39  ALA F O   1 
ATOM   1882 C CB  . ALA B 2 43  ? -24.79099 28.95175  17.75258  1.000 125.65831 ? 39  ALA F CB  1 
ATOM   1883 N N   . VAL B 2 44  ? -24.20843 25.75563  17.74522  1.000 115.59598 ? 40  VAL F N   1 
ATOM   1884 C CA  . VAL B 2 44  ? -24.36502 24.47681  18.42970  1.000 119.17729 ? 40  VAL F CA  1 
ATOM   1885 C C   . VAL B 2 44  ? -23.50076 24.46197  19.67881  1.000 126.72326 ? 40  VAL F C   1 
ATOM   1886 O O   . VAL B 2 44  ? -22.27739 24.61069  19.58198  1.000 130.74324 ? 40  VAL F O   1 
ATOM   1887 C CB  . VAL B 2 44  ? -23.99275 23.29519  17.51867  1.000 119.39384 ? 40  VAL F CB  1 
ATOM   1888 C CG1 . VAL B 2 44  ? -24.18609 22.00834  18.26033  1.000 121.62776 ? 40  VAL F CG1 1 
ATOM   1889 C CG2 . VAL B 2 44  ? -24.83369 23.31744  16.24983  1.000 127.27933 ? 40  VAL F CG2 1 
ATOM   1890 N N   . SER B 2 45  ? -24.12388 24.26280  20.84321  1.000 122.65155 ? 41  SER F N   1 
ATOM   1891 C CA  . SER B 2 45  ? -23.40254 24.18446  22.10713  1.000 108.48610 ? 41  SER F CA  1 
ATOM   1892 C C   . SER B 2 45  ? -23.17496 22.71210  22.43921  1.000 112.73581 ? 41  SER F C   1 
ATOM   1893 O O   . SER B 2 45  ? -24.12747 21.98862  22.75009  1.000 109.96291 ? 41  SER F O   1 
ATOM   1894 C CB  . SER B 2 45  ? -24.18882 24.86889  23.22517  1.000 102.58765 ? 41  SER F CB  1 
ATOM   1895 O OG  . SER B 2 45  ? -24.46752 26.22478  22.93245  1.000 99.70748  ? 41  SER F OG  1 
ATOM   1896 N N   . LYS B 2 46  ? -21.92352 22.26600  22.37180  1.000 120.93618 ? 42  LYS F N   1 
ATOM   1897 C CA  . LYS B 2 46  ? -21.57716 20.87455  22.63488  1.000 123.41969 ? 42  LYS F CA  1 
ATOM   1898 C C   . LYS B 2 46  ? -20.93135 20.77400  24.01756  1.000 122.92547 ? 42  LYS F C   1 
ATOM   1899 O O   . LYS B 2 46  ? -20.58173 21.78176  24.63404  1.000 128.50476 ? 42  LYS F O   1 
ATOM   1900 C CB  . LYS B 2 46  ? -20.68094 20.30559  21.51828  1.000 143.80905 ? 42  LYS F CB  1 
ATOM   1901 C CG  . LYS B 2 46  ? -19.36622 21.02674  21.22140  1.000 142.72212 ? 42  LYS F CG  1 
ATOM   1902 C CD  . LYS B 2 46  ? -18.55962 20.25962  20.15886  1.000 131.26776 ? 42  LYS F CD  1 
ATOM   1903 C CE  . LYS B 2 46  ? -18.42458 18.77175  20.46205  1.000 127.97132 ? 42  LYS F CE  1 
ATOM   1904 N NZ  . LYS B 2 46  ? -17.68436 18.48588  21.71707  1.000 127.56291 ? 42  LYS F NZ  1 
ATOM   1905 N N   . GLY B 2 47  ? -20.76635 19.54582  24.50752  1.000 127.76525 ? 43  GLY F N   1 
ATOM   1906 C CA  . GLY B 2 47  ? -20.03332 19.32299  25.74127  1.000 136.56007 ? 43  GLY F CA  1 
ATOM   1907 C C   . GLY B 2 47  ? -20.85969 19.11192  26.99572  1.000 125.96557 ? 43  GLY F C   1 
ATOM   1908 O O   . GLY B 2 47  ? -20.27813 18.97440  28.08104  1.000 118.32119 ? 43  GLY F O   1 
ATOM   1909 N N   . TYR B 2 48  ? -22.18454 19.09726  26.89067  1.000 123.47377 ? 44  TYR F N   1 
ATOM   1910 C CA  . TYR B 2 48  ? -23.04435 18.93169  28.05459  1.000 122.07324 ? 44  TYR F CA  1 
ATOM   1911 C C   . TYR B 2 48  ? -23.18383 17.45223  28.37662  1.000 133.16197 ? 44  TYR F C   1 
ATOM   1912 O O   . TYR B 2 48  ? -23.21644 16.61217  27.47269  1.000 136.62075 ? 44  TYR F O   1 
ATOM   1913 C CB  . TYR B 2 48  ? -24.43191 19.52514  27.82155  1.000 117.52379 ? 44  TYR F CB  1 
ATOM   1914 C CG  . TYR B 2 48  ? -24.48852 21.02321  27.72770  1.000 113.64225 ? 44  TYR F CG  1 
ATOM   1915 C CD1 . TYR B 2 48  ? -24.23033 21.67772  26.53759  1.000 124.37913 ? 44  TYR F CD1 1 
ATOM   1916 C CD2 . TYR B 2 48  ? -24.82113 21.78389  28.83712  1.000 117.95587 ? 44  TYR F CD2 1 
ATOM   1917 C CE1 . TYR B 2 48  ? -24.29505 23.05184  26.45843  1.000 126.32129 ? 44  TYR F CE1 1 
ATOM   1918 C CE2 . TYR B 2 48  ? -24.88743 23.15303  28.76922  1.000 122.61721 ? 44  TYR F CE2 1 
ATOM   1919 C CZ  . TYR B 2 48  ? -24.62426 23.78398  27.57953  1.000 117.54493 ? 44  TYR F CZ  1 
ATOM   1920 O OH  . TYR B 2 48  ? -24.69200 25.15417  27.51214  1.000 108.03864 ? 44  TYR F OH  1 
ATOM   1921 N N   . LEU B 2 49  ? -23.25258 17.12598  29.66726  1.000 133.90630 ? 45  LEU F N   1 
ATOM   1922 C CA  . LEU B 2 49  ? -23.45281 15.74483  30.08420  1.000 131.71183 ? 45  LEU F CA  1 
ATOM   1923 C C   . LEU B 2 49  ? -24.92943 15.56788  30.43952  1.000 130.69976 ? 45  LEU F C   1 
ATOM   1924 O O   . LEU B 2 49  ? -25.43932 16.21255  31.36225  1.000 134.73845 ? 45  LEU F O   1 
ATOM   1925 C CB  . LEU B 2 49  ? -22.54258 15.41952  31.27225  1.000 131.15997 ? 45  LEU F CB  1 
ATOM   1926 C CG  . LEU B 2 49  ? -21.02624 15.49543  31.01347  1.000 125.20723 ? 45  LEU F CG  1 
ATOM   1927 C CD1 . LEU B 2 49  ? -20.20683 15.20886  32.27234  1.000 122.89039 ? 45  LEU F CD1 1 
ATOM   1928 C CD2 . LEU B 2 49  ? -20.60749 14.56952  29.88325  1.000 129.81443 ? 45  LEU F CD2 1 
ATOM   1929 N N   . GLY B 2 50  ? -25.59518 14.68053  29.70417  1.000 129.53390 ? 46  GLY F N   1 
ATOM   1930 C CA  . GLY B 2 50  ? -27.02742 14.46726  29.78904  1.000 123.43437 ? 46  GLY F CA  1 
ATOM   1931 C C   . GLY B 2 50  ? -27.49705 13.30220  30.64000  1.000 119.40145 ? 46  GLY F C   1 
ATOM   1932 O O   . GLY B 2 50  ? -26.80527 12.28823  30.77211  1.000 125.54652 ? 46  GLY F O   1 
ATOM   1933 N N   . ALA B 2 51  ? -28.71042 13.46777  31.17694  1.000 106.20676 ? 47  ALA F N   1 
ATOM   1934 C CA  . ALA B 2 51  ? -29.46304 12.47014  31.93569  1.000 101.28706 ? 47  ALA F CA  1 
ATOM   1935 C C   . ALA B 2 51  ? -30.89668 12.42860  31.39547  1.000 98.71226  ? 47  ALA F C   1 
ATOM   1936 O O   . ALA B 2 51  ? -31.69081 13.34610  31.64000  1.000 97.78325  ? 47  ALA F O   1 
ATOM   1937 C CB  . ALA B 2 51  ? -29.43802 12.77787  33.42878  1.000 111.47934 ? 47  ALA F CB  1 
ATOM   1938 N N   . LEU B 2 52  ? -31.18681 11.44453  30.55271  1.000 101.69673 ? 48  LEU F N   1 
ATOM   1939 C CA  . LEU B 2 52  ? -32.48258 11.30473  29.89444  1.000 110.96078 ? 48  LEU F CA  1 
ATOM   1940 C C   . LEU B 2 52  ? -33.36085 10.34461  30.69219  1.000 116.86676 ? 48  LEU F C   1 
ATOM   1941 O O   . LEU B 2 52  ? -32.90550 9.26505   31.08564  1.000 117.29287 ? 48  LEU F O   1 
ATOM   1942 C CB  . LEU B 2 52  ? -32.34935 10.82418  28.45079  1.000 114.61240 ? 48  LEU F CB  1 
ATOM   1943 C CG  . LEU B 2 52  ? -31.39196 11.59619  27.54455  1.000 118.32881 ? 48  LEU F CG  1 
ATOM   1944 C CD1 . LEU B 2 52  ? -31.51367 11.08421  26.12448  1.000 118.23646 ? 48  LEU F CD1 1 
ATOM   1945 C CD2 . LEU B 2 52  ? -31.64991 13.09062  27.60481  1.000 126.39111 ? 48  LEU F CD2 1 
ATOM   1946 N N   . ARG B 2 53  ? -34.60649 10.74330  30.94051  1.000 112.57347 ? 49  ARG F N   1 
ATOM   1947 C CA  . ARG B 2 53  ? -35.56046 9.90659   31.65629  1.000 112.14547 ? 49  ARG F CA  1 
ATOM   1948 C C   . ARG B 2 53  ? -36.12868 8.82894   30.74899  1.000 112.76638 ? 49  ARG F C   1 
ATOM   1949 O O   . ARG B 2 53  ? -36.66334 9.12455   29.67591  1.000 115.72114 ? 49  ARG F O   1 
ATOM   1950 C CB  . ARG B 2 53  ? -36.72009 10.75188  32.17921  1.000 111.13616 ? 49  ARG F CB  1 
ATOM   1951 C CG  . ARG B 2 53  ? -37.43120 10.16651  33.37768  1.000 113.29156 ? 49  ARG F CG  1 
ATOM   1952 C CD  . ARG B 2 53  ? -38.92954 10.47366  33.30516  1.000 106.39091 ? 49  ARG F CD  1 
ATOM   1953 N NE  . ARG B 2 53  ? -39.51341 10.12337  32.01158  1.000 96.32222  ? 49  ARG F NE  1 
ATOM   1954 C CZ  . ARG B 2 53  ? -40.02533 8.93796   31.70193  1.000 98.48771  ? 49  ARG F CZ  1 
ATOM   1955 N NH1 . ARG B 2 53  ? -40.02520 7.93693   32.56567  1.000 108.05261 ? 49  ARG F NH1 1 
ATOM   1956 N NH2 . ARG B 2 53  ? -40.55073 8.75269   30.49289  1.000 93.23354  ? 49  ARG F NH2 1 
ATOM   1957 N N   . THR B 2 54  ? -36.01247 7.57135   31.18656  1.000 109.50429 ? 50  THR F N   1 
ATOM   1958 C CA  . THR B 2 54  ? -36.50865 6.44253   30.41482  1.000 111.18526 ? 50  THR F CA  1 
ATOM   1959 C C   . THR B 2 54  ? -37.48317 5.54326   31.15996  1.000 111.83938 ? 50  THR F C   1 
ATOM   1960 O O   . THR B 2 54  ? -38.18095 4.75412   30.51303  1.000 111.15184 ? 50  THR F O   1 
ATOM   1961 C CB  . THR B 2 54  ? -35.33343 5.57157   29.94440  1.000 117.51535 ? 50  THR F CB  1 
ATOM   1962 O OG1 . THR B 2 54  ? -34.65061 5.04822   31.09033  1.000 114.28785 ? 50  THR F OG1 1 
ATOM   1963 C CG2 . THR B 2 54  ? -34.35434 6.39009   29.12144  1.000 119.66335 ? 50  THR F CG2 1 
ATOM   1964 N N   . GLY B 2 55  ? -37.56225 5.64266   32.48519  1.000 115.87093 ? 51  GLY F N   1 
ATOM   1965 C CA  . GLY B 2 55  ? -38.45460 4.81518   33.26856  1.000 114.74524 ? 51  GLY F CA  1 
ATOM   1966 C C   . GLY B 2 55  ? -39.03822 5.57659   34.44152  1.000 114.37964 ? 51  GLY F C   1 
ATOM   1967 O O   . GLY B 2 55  ? -38.70233 6.73686   34.68442  1.000 117.31712 ? 51  GLY F O   1 
ATOM   1968 N N   . TRP B 2 56  ? -39.92997 4.89651   35.16021  1.000 111.62758 ? 52  TRP F N   1 
ATOM   1969 C CA  . TRP B 2 56  ? -40.58875 5.44558   36.33463  1.000 108.52633 ? 52  TRP F CA  1 
ATOM   1970 C C   . TRP B 2 56  ? -40.35688 4.47434   37.48210  1.000 111.43296 ? 52  TRP F C   1 
ATOM   1971 O O   . TRP B 2 56  ? -40.39093 3.25576   37.28965  1.000 116.50140 ? 52  TRP F O   1 
ATOM   1972 C CB  . TRP B 2 56  ? -42.10347 5.64043   36.12548  1.000 110.86917 ? 52  TRP F CB  1 
ATOM   1973 C CG  . TRP B 2 56  ? -42.48284 6.67098   35.09412  1.000 108.66621 ? 52  TRP F CG  1 
ATOM   1974 C CD1 . TRP B 2 56  ? -43.03898 6.43809   33.86723  1.000 111.13357 ? 52  TRP F CD1 1 
ATOM   1975 C CD2 . TRP B 2 56  ? -42.30862 8.08915   35.19090  1.000 108.42881 ? 52  TRP F CD2 1 
ATOM   1976 N NE1 . TRP B 2 56  ? -43.23885 7.62464   33.20426  1.000 114.60598 ? 52  TRP F NE1 1 
ATOM   1977 C CE2 . TRP B 2 56  ? -42.79498 8.65298   33.99331  1.000 110.35424 ? 52  TRP F CE2 1 
ATOM   1978 C CE3 . TRP B 2 56  ? -41.79181 8.93738   36.17479  1.000 107.54592 ? 52  TRP F CE3 1 
ATOM   1979 C CZ2 . TRP B 2 56  ? -42.77958 10.02481  33.75441  1.000 110.03373 ? 52  TRP F CZ2 1 
ATOM   1980 C CZ3 . TRP B 2 56  ? -41.77817 10.29952  35.93590  1.000 107.91641 ? 52  TRP F CZ3 1 
ATOM   1981 C CH2 . TRP B 2 56  ? -42.26893 10.82956  34.73532  1.000 111.15737 ? 52  TRP F CH2 1 
ATOM   1982 N N   . TYR B 2 57  ? -40.13430 5.01061   38.67555  1.000 111.30109 ? 53  TYR F N   1 
ATOM   1983 C CA  . TYR B 2 57  ? -40.04986 4.20767   39.88956  1.000 110.82874 ? 53  TYR F CA  1 
ATOM   1984 C C   . TYR B 2 57  ? -41.15859 4.66409   40.82366  1.000 103.28620 ? 53  TYR F C   1 
ATOM   1985 O O   . TYR B 2 57  ? -41.10536 5.77461   41.36022  1.000 103.04522 ? 53  TYR F O   1 
ATOM   1986 C CB  . TYR B 2 57  ? -38.67333 4.35749   40.53735  1.000 109.73031 ? 53  TYR F CB  1 
ATOM   1987 C CG  . TYR B 2 57  ? -38.51553 3.66094   41.86682  1.000 111.99246 ? 53  TYR F CG  1 
ATOM   1988 C CD1 . TYR B 2 57  ? -38.23277 2.30275   41.93791  1.000 120.83787 ? 53  TYR F CD1 1 
ATOM   1989 C CD2 . TYR B 2 57  ? -38.62955 4.36858   43.05221  1.000 108.66102 ? 53  TYR F CD2 1 
ATOM   1990 C CE1 . TYR B 2 57  ? -38.08184 1.67112   43.15774  1.000 123.59009 ? 53  TYR F CE1 1 
ATOM   1991 C CE2 . TYR B 2 57  ? -38.48100 3.74876   44.27034  1.000 116.07114 ? 53  TYR F CE2 1 
ATOM   1992 C CZ  . TYR B 2 57  ? -38.20605 2.40286   44.32122  1.000 123.36461 ? 53  TYR F CZ  1 
ATOM   1993 O OH  . TYR B 2 57  ? -38.05893 1.79641   45.54723  1.000 121.40375 ? 53  TYR F OH  1 
ATOM   1994 N N   . THR B 2 58  ? -42.16546 3.82221   41.01281  1.000 92.81601  ? 54  THR F N   1 
ATOM   1995 C CA  . THR B 2 58  ? -43.28019 4.20632   41.85877  1.000 91.01512  ? 54  THR F CA  1 
ATOM   1996 C C   . THR B 2 58  ? -43.03682 3.73735   43.28943  1.000 97.16791  ? 54  THR F C   1 
ATOM   1997 O O   . THR B 2 58  ? -42.35127 2.73940   43.52958  1.000 95.14072  ? 54  THR F O   1 
ATOM   1998 C CB  . THR B 2 58  ? -44.58513 3.61558   41.32005  1.000 85.84750  ? 54  THR F CB  1 
ATOM   1999 O OG1 . THR B 2 58  ? -44.49539 2.18625   41.31270  1.000 83.23629  ? 54  THR F OG1 1 
ATOM   2000 C CG2 . THR B 2 58  ? -44.84748 4.09743   39.90425  1.000 84.72336  ? 54  THR F CG2 1 
ATOM   2001 N N   . SER B 2 59  ? -43.59938 4.47807   44.24229  1.000 95.61892  ? 55  SER F N   1 
ATOM   2002 C CA  . SER B 2 59  ? -43.48842 4.14329   45.65481  1.000 86.93037  ? 55  SER F CA  1 
ATOM   2003 C C   . SER B 2 59  ? -44.76374 4.58585   46.35911  1.000 80.03866  ? 55  SER F C   1 
ATOM   2004 O O   . SER B 2 59  ? -45.32135 5.63581   46.03037  1.000 75.92519  ? 55  SER F O   1 
ATOM   2005 C CB  . SER B 2 59  ? -42.25802 4.80041   46.29460  1.000 82.94173  ? 55  SER F CB  1 
ATOM   2006 O OG  . SER B 2 59  ? -42.12261 4.42085   47.65270  1.000 87.95843  ? 55  SER F OG  1 
ATOM   2007 N N   . VAL B 2 60  ? -45.22595 3.78585   47.31776  1.000 84.18464  ? 56  VAL F N   1 
ATOM   2008 C CA  . VAL B 2 60  ? -46.46161 4.07746   48.03995  1.000 78.00121  ? 56  VAL F CA  1 
ATOM   2009 C C   . VAL B 2 60  ? -46.11181 4.82118   49.32307  1.000 82.37084  ? 56  VAL F C   1 
ATOM   2010 O O   . VAL B 2 60  ? -45.24068 4.39460   50.08762  1.000 89.38826  ? 56  VAL F O   1 
ATOM   2011 C CB  . VAL B 2 60  ? -47.25002 2.78891   48.33585  1.000 78.72740  ? 56  VAL F CB  1 
ATOM   2012 C CG1 . VAL B 2 60  ? -48.47926 3.09786   49.17511  1.000 73.91226  ? 56  VAL F CG1 1 
ATOM   2013 C CG2 . VAL B 2 60  ? -47.65525 2.11861   47.03692  1.000 84.63494  ? 56  VAL F CG2 1 
ATOM   2014 N N   . ILE B 2 61  ? -46.77428 5.94685   49.54589  1.000 71.59675  ? 57  ILE F N   1 
ATOM   2015 C CA  . ILE B 2 61  ? -46.61401 6.76923   50.73132  1.000 73.15716  ? 57  ILE F CA  1 
ATOM   2016 C C   . ILE B 2 61  ? -47.93073 6.72999   51.48723  1.000 73.25586  ? 57  ILE F C   1 
ATOM   2017 O O   . ILE B 2 61  ? -48.98017 7.09539   50.93811  1.000 71.87715  ? 57  ILE F O   1 
ATOM   2018 C CB  . ILE B 2 61  ? -46.20793 8.20357   50.36674  1.000 68.16276  ? 57  ILE F CB  1 
ATOM   2019 C CG1 . ILE B 2 61  ? -45.06433 8.18973   49.34854  1.000 64.49860  ? 57  ILE F CG1 1 
ATOM   2020 C CG2 . ILE B 2 61  ? -45.83406 8.98659   51.59780  1.000 77.87983  ? 57  ILE F CG2 1 
ATOM   2021 C CD1 . ILE B 2 61  ? -43.79972 7.50684   49.84913  1.000 66.47513  ? 57  ILE F CD1 1 
ATOM   2022 N N   . THR B 2 62  ? -47.89040 6.21210   52.71096  1.000 73.46147  ? 58  THR F N   1 
ATOM   2023 C CA  . THR B 2 62  ? -49.07952 6.05017   53.52816  1.000 69.98298  ? 58  THR F CA  1 
ATOM   2024 C C   . THR B 2 62  ? -49.07782 7.03106   54.69338  1.000 69.42780  ? 58  THR F C   1 
ATOM   2025 O O   . THR B 2 62  ? -48.02532 7.40632   55.21873  1.000 70.27959  ? 58  THR F O   1 
ATOM   2026 C CB  . THR B 2 62  ? -49.17670 4.62359   54.07409  1.000 73.15923  ? 58  THR F CB  1 
ATOM   2027 O OG1 . THR B 2 62  ? -48.14414 4.41537   55.04640  1.000 75.89492  ? 58  THR F OG1 1 
ATOM   2028 C CG2 . THR B 2 62  ? -49.01460 3.61267   52.95220  1.000 75.30702  ? 58  THR F CG2 1 
ATOM   2029 N N   . ILE B 2 63  ? -50.27963 7.44159   55.08549  1.000 66.48548  ? 59  ILE F N   1 
ATOM   2030 C CA  . ILE B 2 63  ? -50.51351 8.25374   56.26967  1.000 73.09731  ? 59  ILE F CA  1 
ATOM   2031 C C   . ILE B 2 63  ? -51.62305 7.57599   57.06164  1.000 76.37024  ? 59  ILE F C   1 
ATOM   2032 O O   . ILE B 2 63  ? -52.75328 7.43705   56.57126  1.000 72.34491  ? 59  ILE F O   1 
ATOM   2033 C CB  . ILE B 2 63  ? -50.87867 9.70417   55.92244  1.000 64.89073  ? 59  ILE F CB  1 
ATOM   2034 C CG1 . ILE B 2 63  ? -49.65712 10.41046  55.33640  1.000 64.07435  ? 59  ILE F CG1 1 
ATOM   2035 C CG2 . ILE B 2 63  ? -51.36682 10.44188  57.16104  1.000 68.27930  ? 59  ILE F CG2 1 
ATOM   2036 C CD1 . ILE B 2 63  ? -49.89430 11.85786  55.02870  1.000 73.41903  ? 59  ILE F CD1 1 
ATOM   2037 N N   . GLU B 2 64  ? -51.28740 7.11470   58.25823  1.000 79.88525  ? 60  GLU F N   1 
ATOM   2038 C CA  . GLU B 2 64  ? -52.22678 6.40409   59.11561  1.000 79.80587  ? 60  GLU F CA  1 
ATOM   2039 C C   . GLU B 2 64  ? -53.22587 7.40565   59.69004  1.000 74.63253  ? 60  GLU F C   1 
ATOM   2040 O O   . GLU B 2 64  ? -52.84988 8.27291   60.48464  1.000 74.17823  ? 60  GLU F O   1 
ATOM   2041 C CB  . GLU B 2 64  ? -51.44343 5.67207   60.20127  1.000 85.05749  ? 60  GLU F CB  1 
ATOM   2042 C CG  . GLU B 2 64  ? -52.07529 4.39666   60.70975  1.000 89.09724  ? 60  GLU F CG  1 
ATOM   2043 C CD  . GLU B 2 64  ? -51.10930 3.58610   61.55595  1.000 99.57924  ? 60  GLU F CD  1 
ATOM   2044 O OE1 . GLU B 2 64  ? -49.97567 4.06047   61.78806  1.000 102.15807 ? 60  GLU F OE1 1 
ATOM   2045 O OE2 . GLU B 2 64  ? -51.47312 2.46640   61.96887  1.000 111.78258 ? 60  GLU F OE2 1 
ATOM   2046 N N   . LEU B 2 65  ? -54.49680 7.29058   59.31071  1.000 73.01682  ? 61  LEU F N   1 
ATOM   2047 C CA  . LEU B 2 65  ? -55.52005 8.22868   59.75577  1.000 69.54248  ? 61  LEU F CA  1 
ATOM   2048 C C   . LEU B 2 65  ? -56.39314 7.61943   60.84963  1.000 73.54020  ? 61  LEU F C   1 
ATOM   2049 O O   . LEU B 2 65  ? -56.31888 6.42561   61.14007  1.000 79.77720  ? 61  LEU F O   1 
ATOM   2050 C CB  . LEU B 2 65  ? -56.39100 8.64454   58.57068  1.000 68.45689  ? 61  LEU F CB  1 
ATOM   2051 C CG  . LEU B 2 65  ? -55.67040 9.44055   57.49301  1.000 70.67378  ? 61  LEU F CG  1 
ATOM   2052 C CD1 . LEU B 2 65  ? -56.66936 9.88916   56.44038  1.000 70.42806  ? 61  LEU F CD1 1 
ATOM   2053 C CD2 . LEU B 2 65  ? -54.94129 10.61791  58.11796  1.000 74.69343  ? 61  LEU F CD2 1 
ATOM   2054 N N   . SER B 2 66  ? -57.17889 8.47791   61.51103  1.000 71.28248  ? 62  SER F N   1 
ATOM   2055 C CA  . SER B 2 66  ? -58.06616 8.06036   62.59608  1.000 76.15593  ? 62  SER F CA  1 
ATOM   2056 C C   . SER B 2 66  ? -59.54935 8.20006   62.24090  1.000 78.48711  ? 62  SER F C   1 
ATOM   2057 O O   . SER B 2 66  ? -60.03782 9.30476   61.97891  1.000 74.04590  ? 62  SER F O   1 
ATOM   2058 C CB  . SER B 2 66  ? -57.76088 8.83902   63.87429  1.000 83.35957  ? 62  SER F CB  1 
ATOM   2059 O OG  . SER B 2 66  ? -58.55723 8.36140   64.94313  1.000 78.75527  ? 62  SER F OG  1 
ATOM   2060 N N   . ASN B 2 67  ? -60.24929 7.07567   62.25524  1.000 78.51417  ? 63  ASN F N   1 
ATOM   2061 C CA  . ASN B 2 67  ? -61.68751 6.91966   62.02375  1.000 75.04860  ? 63  ASN F CA  1 
ATOM   2062 C C   . ASN B 2 67  ? -62.37151 7.26448   63.34193  1.000 69.92789  ? 63  ASN F C   1 
ATOM   2063 O O   . ASN B 2 67  ? -62.37375 6.44994   64.26132  1.000 76.00652  ? 63  ASN F O   1 
ATOM   2064 C CB  . ASN B 2 67  ? -62.04693 5.52559   61.52075  1.000 73.13372  ? 63  ASN F CB  1 
ATOM   2065 C CG  . ASN B 2 67  ? -62.02658 5.42750   59.98697  1.000 91.97150  ? 63  ASN F CG  1 
ATOM   2066 O OD1 . ASN B 2 67  ? -61.78651 6.41692   59.28815  1.000 98.76600  ? 63  ASN F OD1 1 
ATOM   2067 N ND2 . ASN B 2 67  ? -62.26159 4.22690   59.46641  1.000 98.34108  ? 63  ASN F ND2 1 
ATOM   2068 N N   . ILE B 2 68  ? -62.85588 8.49272   63.52617  1.000 65.83438  ? 64  ILE F N   1 
ATOM   2069 C CA  . ILE B 2 68  ? -63.46732 8.78402   64.81765  1.000 73.52413  ? 64  ILE F CA  1 
ATOM   2070 C C   . ILE B 2 68  ? -64.87863 9.33234   64.68740  1.000 70.60381  ? 64  ILE F C   1 
ATOM   2071 O O   . ILE B 2 68  ? -65.27302 9.92341   63.67658  1.000 71.49942  ? 64  ILE F O   1 
ATOM   2072 C CB  . ILE B 2 68  ? -62.63308 9.80612   65.60812  1.000 77.96622  ? 64  ILE F CB  1 
ATOM   2073 C CG1 . ILE B 2 68  ? -62.49635 11.08119  64.77954  1.000 70.01302  ? 64  ILE F CG1 1 
ATOM   2074 C CG2 . ILE B 2 68  ? -61.27931 9.23545   65.93766  1.000 82.18004  ? 64  ILE F CG2 1 
ATOM   2075 C CD1 . ILE B 2 68  ? -62.10316 12.28337  65.57911  1.000 62.85488  ? 64  ILE F CD1 1 
ATOM   2076 N N   . LYS B 2 69  ? -65.64373 9.08528   65.74808  1.000 69.95683  ? 65  LYS F N   1 
ATOM   2077 C CA  . LYS B 2 69  ? -67.00506 9.56433   65.94990  1.000 77.58067  ? 65  LYS F CA  1 
ATOM   2078 C C   . LYS B 2 69  ? -67.04851 10.52564  67.13684  1.000 85.54668  ? 65  LYS F C   1 
ATOM   2079 O O   . LYS B 2 69  ? -67.52017 10.15398  68.21516  1.000 94.30962  ? 65  LYS F O   1 
ATOM   2080 C CB  . LYS B 2 69  ? -67.91979 8.36481   66.21355  1.000 87.45752  ? 65  LYS F CB  1 
ATOM   2081 C CG  . LYS B 2 69  ? -67.99701 7.34462   65.09908  1.000 98.05236  ? 65  LYS F CG  1 
ATOM   2082 C CD  . LYS B 2 69  ? -69.21430 6.43706   65.25491  1.000 109.18671 ? 65  LYS F CD  1 
ATOM   2083 C CE  . LYS B 2 69  ? -69.13060 5.63498   66.55055  1.000 102.69479 ? 65  LYS F CE  1 
ATOM   2084 N NZ  . LYS B 2 69  ? -67.90266 4.79479   66.59576  1.000 80.45640  ? 65  LYS F NZ  1 
ATOM   2085 N N   . GLU B 2 70  ? -66.56002 11.74999  66.95101  1.000 93.51321  ? 66  GLU F N   1 
ATOM   2086 C CA  . GLU B 2 70  ? -66.48511 12.68341  68.07025  1.000 108.70992 ? 66  GLU F CA  1 
ATOM   2087 C C   . GLU B 2 70  ? -67.90598 12.98456  68.52673  1.000 113.15068 ? 66  GLU F C   1 
ATOM   2088 O O   . GLU B 2 70  ? -68.81410 13.12355  67.70213  1.000 96.42202  ? 66  GLU F O   1 
ATOM   2089 C CB  . GLU B 2 70  ? -65.76716 13.98546  67.73674  1.000 105.57646 ? 66  GLU F CB  1 
ATOM   2090 C CG  . GLU B 2 70  ? -65.37805 14.68300  69.05404  1.000 102.61049 ? 66  GLU F CG  1 
ATOM   2091 C CD  . GLU B 2 70  ? -65.93111 16.07858  69.22225  1.000 107.98018 ? 66  GLU F CD  1 
ATOM   2092 O OE1 . GLU B 2 70  ? -66.55631 16.59642  68.27000  1.000 105.61913 ? 66  GLU F OE1 1 
ATOM   2093 O OE2 . GLU B 2 70  ? -65.76062 16.63626  70.33450  1.000 109.05370 ? 66  GLU F OE2 1 
ATOM   2094 N N   . ASN B 2 71  ? -68.11266 13.07499  69.83833  1.000 120.25907 ? 67  ASN F N   1 
ATOM   2095 C CA  . ASN B 2 71  ? -69.45092 13.36367  70.32600  1.000 132.43553 ? 67  ASN F CA  1 
ATOM   2096 C C   . ASN B 2 71  ? -69.52015 14.55501  71.27395  1.000 137.91560 ? 67  ASN F C   1 
ATOM   2097 O O   . ASN B 2 71  ? -68.67274 14.74493  72.15534  1.000 122.30283 ? 67  ASN F O   1 
ATOM   2098 C CB  . ASN B 2 71  ? -69.97634 12.11212  71.06654  1.000 143.22040 ? 67  ASN F CB  1 
ATOM   2099 C CG  . ASN B 2 71  ? -71.45502 12.17963  71.38273  1.000 152.09318 ? 67  ASN F CG  1 
ATOM   2100 O OD1 . ASN B 2 71  ? -72.19290 12.96652  70.80230  1.000 149.27130 ? 67  ASN F OD1 1 
ATOM   2101 N ND2 . ASN B 2 71  ? -71.89134 11.35597  72.33063  1.000 147.89539 ? 67  ASN F ND2 1 
ATOM   2102 N N   . LYS B 2 72  ? -70.56528 15.35180  71.02645  1.000 148.17537 ? 68  LYS F N   1 
ATOM   2103 C CA  . LYS B 2 72  ? -71.00864 16.58181  71.67489  1.000 144.29786 ? 68  LYS F CA  1 
ATOM   2104 C C   . LYS B 2 72  ? -70.80115 16.63524  73.17973  1.000 150.90694 ? 68  LYS F C   1 
ATOM   2105 O O   . LYS B 2 72  ? -71.21760 15.72155  73.89388  1.000 156.07612 ? 68  LYS F O   1 
ATOM   2106 C CB  . LYS B 2 72  ? -72.50479 16.82906  71.41571  1.000 130.82727 ? 68  LYS F CB  1 
ATOM   2107 C CG  . LYS B 2 72  ? -73.35636 15.57539  71.46313  1.000 123.40773 ? 68  LYS F CG  1 
ATOM   2108 C CD  . LYS B 2 72  ? -74.84061 15.87606  71.47137  1.000 128.02630 ? 68  LYS F CD  1 
ATOM   2109 C CE  . LYS B 2 72  ? -75.63520 14.59302  71.65715  1.000 128.57490 ? 68  LYS F CE  1 
ATOM   2110 N NZ  . LYS B 2 72  ? -77.10435 14.82111  71.72395  1.000 121.41586 ? 68  LYS F NZ  1 
ATOM   2111 N N   . CYS B 2 73  ? -70.15138 17.68621  73.66767  1.000 151.45866 ? 69  CYS F N   1 
ATOM   2112 C CA  . CYS B 2 73  ? -70.04023 17.87015  75.10562  1.000 152.10090 ? 69  CYS F CA  1 
ATOM   2113 C C   . CYS B 2 73  ? -70.43196 19.30753  75.39715  1.000 150.28244 ? 69  CYS F C   1 
ATOM   2114 O O   . CYS B 2 73  ? -70.57166 20.10784  74.47963  1.000 151.34429 ? 69  CYS F O   1 
ATOM   2115 C CB  . CYS B 2 73  ? -68.56927 17.70951  75.53488  1.000 139.70731 ? 69  CYS F CB  1 
ATOM   2116 S SG  . CYS B 2 73  ? -67.52153 18.77990  74.44913  1.000 148.85702 ? 69  CYS F SG  1 
ATOM   2117 N N   . ASN B 2 74  ? -70.71380 19.63585  76.65231  1.000 150.37683 ? 70  ASN F N   1 
ATOM   2118 C CA  . ASN B 2 74  ? -70.95768 21.03476  76.98669  1.000 148.80200 ? 70  ASN F CA  1 
ATOM   2119 C C   . ASN B 2 74  ? -69.60702 21.74044  76.85302  1.000 138.47448 ? 70  ASN F C   1 
ATOM   2120 O O   . ASN B 2 74  ? -68.77664 21.64045  77.76477  1.000 129.44413 ? 70  ASN F O   1 
ATOM   2121 C CB  . ASN B 2 74  ? -71.69596 21.12915  78.31131  1.000 149.67565 ? 70  ASN F CB  1 
ATOM   2122 C CG  . ASN B 2 74  ? -72.91196 20.17976  78.31018  1.000 154.13652 ? 70  ASN F CG  1 
ATOM   2123 O OD1 . ASN B 2 74  ? -73.52187 19.93426  77.26554  1.000 155.45464 ? 70  ASN F OD1 1 
ATOM   2124 N ND2 . ASN B 2 74  ? -73.24135 19.62650  79.47529  1.000 151.75911 ? 70  ASN F ND2 1 
ATOM   2125 N N   . GLY B 2 75  ? -69.42464 22.52828  75.80696  1.000 133.78106 ? 71  GLY F N   1 
ATOM   2126 C CA  . GLY B 2 75  ? -68.17529 23.24971  75.59525  1.000 119.43208 ? 71  GLY F CA  1 
ATOM   2127 C C   . GLY B 2 75  ? -68.43804 24.69830  75.24467  1.000 115.55831 ? 71  GLY F C   1 
ATOM   2128 O O   . GLY B 2 75  ? -69.26866 25.00843  74.39329  1.000 118.37984 ? 71  GLY F O   1 
ATOM   2129 N N   . THR B 2 76  ? -67.67288 25.55516  75.84100  1.000 105.68473 ? 72  THR F N   1 
ATOM   2130 C CA  . THR B 2 76  ? -67.73117 27.01055  75.74579  1.000 99.68260  ? 72  THR F CA  1 
ATOM   2131 C C   . THR B 2 76  ? -66.33622 27.59085  75.75733  1.000 91.42495  ? 72  THR F C   1 
ATOM   2132 O O   . THR B 2 76  ? -66.10352 28.56852  75.03925  1.000 81.80547  ? 72  THR F O   1 
ATOM   2133 C CB  . THR B 2 76  ? -68.65304 27.73003  76.75388  1.000 111.91614 ? 72  THR F CB  1 
ATOM   2134 O OG1 . THR B 2 76  ? -68.38030 27.36035  78.09858  1.000 114.81299 ? 72  THR F OG1 1 
ATOM   2135 C CG2 . THR B 2 76  ? -70.13781 27.41742  76.39998  1.000 114.37771 ? 72  THR F CG2 1 
ATOM   2136 N N   . ASP B 2 77  ? -65.49593 27.19888  76.71909  1.000 96.48085  ? 73  ASP F N   1 
ATOM   2137 C CA  . ASP B 2 77  ? -64.17459 27.77967  76.86162  1.000 98.44047  ? 73  ASP F CA  1 
ATOM   2138 C C   . ASP B 2 77  ? -63.36471 27.62619  75.57788  1.000 94.41334  ? 73  ASP F C   1 
ATOM   2139 O O   . ASP B 2 77  ? -63.56768 26.70590  74.77690  1.000 94.81635  ? 73  ASP F O   1 
ATOM   2140 C CB  . ASP B 2 77  ? -63.45664 26.97254  77.95592  1.000 98.54297  ? 73  ASP F CB  1 
ATOM   2141 C CG  . ASP B 2 77  ? -62.07061 27.46126  78.24013  1.000 104.81121 ? 73  ASP F CG  1 
ATOM   2142 O OD1 . ASP B 2 77  ? -61.80390 28.66825  78.06730  1.000 115.15335 ? 73  ASP F OD1 1 
ATOM   2143 O OD2 . ASP B 2 77  ? -61.23364 26.60952  78.60951  1.000 100.11246 ? 73  ASP F OD2 1 
ATOM   2144 N N   . ALA B 2 78  ? -62.49306 28.62026  75.34836  1.000 91.40728  ? 74  ALA F N   1 
ATOM   2145 C CA  . ALA B 2 78  ? -61.89634 28.76377  74.02258  1.000 86.50012  ? 74  ALA F CA  1 
ATOM   2146 C C   . ALA B 2 78  ? -61.08697 27.54205  73.63050  1.000 74.49845  ? 74  ALA F C   1 
ATOM   2147 O O   . ALA B 2 78  ? -60.94800 27.24475  72.44231  1.000 76.10103  ? 74  ALA F O   1 
ATOM   2148 C CB  . ALA B 2 78  ? -61.02133 30.01978  73.96940  1.000 99.12295  ? 74  ALA F CB  1 
ATOM   2149 N N   . LYS B 2 79  ? -60.55563 26.81994  74.61218  1.000 73.05912  ? 75  LYS F N   1 
ATOM   2150 C CA  . LYS B 2 79  ? -59.72851 25.65869  74.31362  1.000 80.64250  ? 75  LYS F CA  1 
ATOM   2151 C C   . LYS B 2 79  ? -60.53647 24.49914  73.74283  1.000 79.53308  ? 75  LYS F C   1 
ATOM   2152 O O   . LYS B 2 79  ? -60.11131 23.85662  72.77356  1.000 75.30153  ? 75  LYS F O   1 
ATOM   2153 C CB  . LYS B 2 79  ? -59.01420 25.22940  75.58502  1.000 92.80831  ? 75  LYS F CB  1 
ATOM   2154 C CG  . LYS B 2 79  ? -58.18626 26.32329  76.26126  1.000 88.81201  ? 75  LYS F CG  1 
ATOM   2155 C CD  . LYS B 2 79  ? -58.10051 25.98801  77.75443  1.000 89.83554  ? 75  LYS F CD  1 
ATOM   2156 C CE  . LYS B 2 79  ? -57.43947 27.06737  78.59696  1.000 89.00385  ? 75  LYS F CE  1 
ATOM   2157 N NZ  . LYS B 2 79  ? -56.04665 27.29674  78.13055  1.000 93.91382  ? 75  LYS F NZ  1 
ATOM   2158 N N   . VAL B 2 80  ? -61.75470 24.29440  74.24797  1.000 75.54488  ? 76  VAL F N   1 
ATOM   2159 C CA  . VAL B 2 80  ? -62.59384 23.23715  73.69862  1.000 73.59597  ? 76  VAL F CA  1 
ATOM   2160 C C   . VAL B 2 80  ? -63.03497 23.58985  72.29024  1.000 74.54445  ? 76  VAL F C   1 
ATOM   2161 O O   . VAL B 2 80  ? -63.04369 22.73603  71.39911  1.000 81.89945  ? 76  VAL F O   1 
ATOM   2162 C CB  . VAL B 2 80  ? -63.78190 22.96116  74.63778  1.000 88.20594  ? 76  VAL F CB  1 
ATOM   2163 C CG1 . VAL B 2 80  ? -64.77393 22.00988  73.98035  1.000 101.30961 ? 76  VAL F CG1 1 
ATOM   2164 C CG2 . VAL B 2 80  ? -63.28554 22.41563  75.99118  1.000 88.34950  ? 76  VAL F CG2 1 
ATOM   2165 N N   . LYS B 2 81  ? -63.40604 24.85149  72.06449  1.000 72.65647  ? 77  LYS F N   1 
ATOM   2166 C CA  . LYS B 2 81  ? -63.77646 25.26789  70.71589  1.000 80.75256  ? 77  LYS F CA  1 
ATOM   2167 C C   . LYS B 2 81  ? -62.60007 25.14788  69.75553  1.000 76.59734  ? 77  LYS F C   1 
ATOM   2168 O O   . LYS B 2 81  ? -62.78485 24.73830  68.61040  1.000 77.11427  ? 77  LYS F O   1 
ATOM   2169 C CB  . LYS B 2 81  ? -64.41506 26.65751  70.71970  1.000 88.22719  ? 77  LYS F CB  1 
ATOM   2170 C CG  . LYS B 2 81  ? -65.83063 26.58975  71.32436  1.000 109.18583 ? 77  LYS F CG  1 
ATOM   2171 C CD  . LYS B 2 81  ? -66.68349 25.62873  70.45411  1.000 108.33611 ? 77  LYS F CD  1 
ATOM   2172 C CE  . LYS B 2 81  ? -68.12284 25.39925  70.92895  1.000 90.41869  ? 77  LYS F CE  1 
ATOM   2173 N NZ  . LYS B 2 81  ? -68.21994 24.76138  72.26407  1.000 85.50593  ? 77  LYS F NZ  1 
ATOM   2174 N N   . LEU B 2 82  ? -61.39512 25.54634  70.17443  1.000 74.69916  ? 78  LEU F N   1 
ATOM   2175 C CA  . LEU B 2 82  ? -60.25325 25.45602  69.26585  1.000 68.91948  ? 78  LEU F CA  1 
ATOM   2176 C C   . LEU B 2 82  ? -59.97055 24.00371  68.91031  1.000 71.08574  ? 78  LEU F C   1 
ATOM   2177 O O   . LEU B 2 82  ? -59.69498 23.67656  67.74667  1.000 70.68398  ? 78  LEU F O   1 
ATOM   2178 C CB  . LEU B 2 82  ? -59.00449 26.08360  69.88563  1.000 56.79148  ? 78  LEU F CB  1 
ATOM   2179 C CG  . LEU B 2 82  ? -58.86375 27.59369  70.03880  1.000 50.77864  ? 78  LEU F CG  1 
ATOM   2180 C CD1 . LEU B 2 82  ? -57.65070 27.88707  70.89291  1.000 54.20151  ? 78  LEU F CD1 1 
ATOM   2181 C CD2 . LEU B 2 82  ? -58.72495 28.25420  68.68657  1.000 49.32289  ? 78  LEU F CD2 1 
ATOM   2182 N N   . ILE B 2 83  ? -60.07028 23.10992  69.89623  1.000 70.64475  ? 79  ILE F N   1 
ATOM   2183 C CA  . ILE B 2 83  ? -59.85019 21.69686  69.61866  1.000 68.09896  ? 79  ILE F CA  1 
ATOM   2184 C C   . ILE B 2 83  ? -60.91588 21.18534  68.65982  1.000 72.67149  ? 79  ILE F C   1 
ATOM   2185 O O   . ILE B 2 83  ? -60.60844 20.50954  67.67636  1.000 75.08610  ? 79  ILE F O   1 
ATOM   2186 C CB  . ILE B 2 83  ? -59.81689 20.88503  70.92411  1.000 70.41404  ? 79  ILE F CB  1 
ATOM   2187 C CG1 . ILE B 2 83  ? -58.44312 21.00695  71.57743  1.000 68.29873  ? 79  ILE F CG1 1 
ATOM   2188 C CG2 . ILE B 2 83  ? -60.09385 19.42245  70.63492  1.000 70.30039  ? 79  ILE F CG2 1 
ATOM   2189 C CD1 . ILE B 2 83  ? -57.31002 20.48420  70.72022  1.000 62.42260  ? 79  ILE F CD1 1 
ATOM   2190 N N   . LYS B 2 84  ? -62.18426 21.51146  68.92663  1.000 74.55585  ? 80  LYS F N   1 
ATOM   2191 C CA  . LYS B 2 84  ? -63.27380 21.06571  68.06257  1.000 72.26083  ? 80  LYS F CA  1 
ATOM   2192 C C   . LYS B 2 84  ? -63.18649 21.67283  66.66637  1.000 70.62775  ? 80  LYS F C   1 
ATOM   2193 O O   . LYS B 2 84  ? -63.55350 21.01943  65.69004  1.000 75.16635  ? 80  LYS F O   1 
ATOM   2194 C CB  . LYS B 2 84  ? -64.62528 21.40993  68.69260  1.000 74.26371  ? 80  LYS F CB  1 
ATOM   2195 C CG  . LYS B 2 84  ? -64.91135 20.74332  70.02955  1.000 85.32868  ? 80  LYS F CG  1 
ATOM   2196 C CD  . LYS B 2 84  ? -66.15727 19.89685  69.95818  1.000 102.58301 ? 80  LYS F CD  1 
ATOM   2197 C CE  . LYS B 2 84  ? -66.63564 19.53608  71.33518  1.000 96.67882  ? 80  LYS F CE  1 
ATOM   2198 N NZ  . LYS B 2 84  ? -67.15832 20.72755  72.06301  1.000 87.19961  ? 80  LYS F NZ  1 
ATOM   2199 N N   . GLN B 2 85  ? -62.69154 22.90412  66.54848  1.000 71.45690  ? 81  GLN F N   1 
ATOM   2200 C CA  . GLN B 2 85  ? -62.48390 23.52611  65.24399  1.000 74.09914  ? 81  GLN F CA  1 
ATOM   2201 C C   . GLN B 2 85  ? -61.41912 22.79938  64.44160  1.000 73.14402  ? 81  GLN F C   1 
ATOM   2202 O O   . GLN B 2 85  ? -61.63204 22.44468  63.27245  1.000 72.06804  ? 81  GLN F O   1 
ATOM   2203 C CB  . GLN B 2 85  ? -62.04184 24.97987  65.42750  1.000 84.21330  ? 81  GLN F CB  1 
ATOM   2204 C CG  . GLN B 2 85  ? -63.09527 25.99226  65.80045  1.000 89.87396  ? 81  GLN F CG  1 
ATOM   2205 C CD  . GLN B 2 85  ? -62.54158 27.40899  65.75983  1.000 98.95262  ? 81  GLN F CD  1 
ATOM   2206 O OE1 . GLN B 2 85  ? -61.44074 27.64269  65.25578  1.000 92.88059  ? 81  GLN F OE1 1 
ATOM   2207 N NE2 . GLN B 2 85  ? -63.28854 28.35481  66.31561  1.000 116.40521 ? 81  GLN F NE2 1 
ATOM   2208 N N   . GLU B 2 86  ? -60.25860 22.56864  65.05569  1.000 71.93082  ? 82  GLU F N   1 
ATOM   2209 C CA  . GLU B 2 86  ? -59.22173 21.83524  64.34744  1.000 77.74596  ? 82  GLU F CA  1 
ATOM   2210 C C   . GLU B 2 86  ? -59.65663 20.39884  64.07309  1.000 76.79698  ? 82  GLU F C   1 
ATOM   2211 O O   . GLU B 2 86  ? -59.33467 19.83333  63.01737  1.000 81.85677  ? 82  GLU F O   1 
ATOM   2212 C CB  . GLU B 2 86  ? -57.93514 21.88140  65.17212  1.000 70.73994  ? 82  GLU F CB  1 
ATOM   2213 C CG  . GLU B 2 86  ? -56.71387 21.31789  64.48544  1.000 78.41593  ? 82  GLU F CG  1 
ATOM   2214 C CD  . GLU B 2 86  ? -56.27079 22.17588  63.31441  1.000 87.69002  ? 82  GLU F CD  1 
ATOM   2215 O OE1 . GLU B 2 86  ? -56.63023 23.37350  63.28545  1.000 97.15506  ? 82  GLU F OE1 1 
ATOM   2216 O OE2 . GLU B 2 86  ? -55.55434 21.66001  62.43098  1.000 83.73569  ? 82  GLU F OE2 1 
ATOM   2217 N N   . LEU B 2 87  ? -60.47787 19.83509  64.95836  1.000 69.90387  ? 83  LEU F N   1 
ATOM   2218 C CA  . LEU B 2 87  ? -60.98617 18.48654  64.76624  1.000 69.29315  ? 83  LEU F CA  1 
ATOM   2219 C C   . LEU B 2 87  ? -61.98192 18.43508  63.61715  1.000 74.54232  ? 83  LEU F C   1 
ATOM   2220 O O   . LEU B 2 87  ? -62.03637 17.44525  62.87504  1.000 71.34375  ? 83  LEU F O   1 
ATOM   2221 C CB  . LEU B 2 87  ? -61.63213 18.03534  66.07801  1.000 74.14800  ? 83  LEU F CB  1 
ATOM   2222 C CG  . LEU B 2 87  ? -61.70233 16.59005  66.55755  1.000 77.35125  ? 83  LEU F CG  1 
ATOM   2223 C CD1 . LEU B 2 87  ? -60.30561 16.04563  66.80259  1.000 70.11092  ? 83  LEU F CD1 1 
ATOM   2224 C CD2 . LEU B 2 87  ? -62.53482 16.52264  67.82889  1.000 78.97845  ? 83  LEU F CD2 1 
ATOM   2225 N N   . ASP B 2 88  ? -62.75346 19.50905  63.43853  1.000 77.84201  ? 84  ASP F N   1 
ATOM   2226 C CA  . ASP B 2 88  ? -63.67715 19.57740  62.31788  1.000 79.74125  ? 84  ASP F CA  1 
ATOM   2227 C C   . ASP B 2 88  ? -62.92574 19.75326  61.00870  1.000 80.03822  ? 84  ASP F C   1 
ATOM   2228 O O   . ASP B 2 88  ? -63.34275 19.22298  59.97297  1.000 88.93274  ? 84  ASP F O   1 
ATOM   2229 C CB  . ASP B 2 88  ? -64.67111 20.72478  62.52820  1.000 80.44019  ? 84  ASP F CB  1 
ATOM   2230 C CG  . ASP B 2 88  ? -65.67063 20.44870  63.64524  1.000 84.12965  ? 84  ASP F CG  1 
ATOM   2231 O OD1 . ASP B 2 88  ? -65.86734 19.26919  64.00834  1.000 86.97657  ? 84  ASP F OD1 1 
ATOM   2232 O OD2 . ASP B 2 88  ? -66.25606 21.42081  64.16803  1.000 85.48357  ? 84  ASP F OD2 1 
ATOM   2233 N N   . LYS B 2 89  ? -61.82018 20.50545  61.02749  1.000 73.14055  ? 85  LYS F N   1 
ATOM   2234 C CA  . LYS B 2 89  ? -61.01847 20.57675  59.81222  1.000 75.32920  ? 85  LYS F CA  1 
ATOM   2235 C C   . LYS B 2 89  ? -60.39614 19.22938  59.46998  1.000 74.31405  ? 85  LYS F C   1 
ATOM   2236 O O   . LYS B 2 89  ? -60.34607 18.85373  58.29166  1.000 79.40468  ? 85  LYS F O   1 
ATOM   2237 C CB  . LYS B 2 89  ? -59.93824 21.65411  59.93796  1.000 70.32761  ? 85  LYS F CB  1 
ATOM   2238 C CG  . LYS B 2 89  ? -60.47470 23.07723  59.79137  1.000 79.04806  ? 85  LYS F CG  1 
ATOM   2239 C CD  . LYS B 2 89  ? -59.74000 24.07288  60.68179  1.000 78.21207  ? 85  LYS F CD  1 
ATOM   2240 C CE  . LYS B 2 89  ? -58.29137 24.23891  60.23165  1.000 77.79019  ? 85  LYS F CE  1 
ATOM   2241 N NZ  . LYS B 2 89  ? -57.50517 25.17042  61.09198  1.000 88.11393  ? 85  LYS F NZ  1 
ATOM   2242 N N   . TYR B 2 90  ? -60.07166 18.42309  60.48191  1.000 69.17828  ? 86  TYR F N   1 
ATOM   2243 C CA  . TYR B 2 90  ? -59.64783 17.05569  60.19113  1.000 68.44246  ? 86  TYR F CA  1 
ATOM   2244 C C   . TYR B 2 90  ? -60.77713 16.18625  59.63926  1.000 71.82319  ? 86  TYR F C   1 
ATOM   2245 O O   . TYR B 2 90  ? -60.56996 15.44613  58.66467  1.000 68.60442  ? 86  TYR F O   1 
ATOM   2246 C CB  . TYR B 2 90  ? -59.06386 16.43096  61.45632  1.000 68.87086  ? 86  TYR F CB  1 
ATOM   2247 C CG  . TYR B 2 90  ? -58.84642 14.94443  61.35872  1.000 61.67471  ? 86  TYR F CG  1 
ATOM   2248 C CD1 . TYR B 2 90  ? -57.69442 14.42852  60.79034  1.000 57.59066  ? 86  TYR F CD1 1 
ATOM   2249 C CD2 . TYR B 2 90  ? -59.79052 14.05429  61.85942  1.000 64.52041  ? 86  TYR F CD2 1 
ATOM   2250 C CE1 . TYR B 2 90  ? -57.49511 13.06991  60.70497  1.000 62.88983  ? 86  TYR F CE1 1 
ATOM   2251 C CE2 . TYR B 2 90  ? -59.59972 12.69577  61.77958  1.000 65.83135  ? 86  TYR F CE2 1 
ATOM   2252 C CZ  . TYR B 2 90  ? -58.45043 12.20951  61.20216  1.000 67.72700  ? 86  TYR F CZ  1 
ATOM   2253 O OH  . TYR B 2 90  ? -58.25892 10.85338  61.12187  1.000 73.13845  ? 86  TYR F OH  1 
ATOM   2254 N N   . LYS B 2 91  ? -62.00178 16.34067  60.15295  1.000 77.94356  ? 87  LYS F N   1 
ATOM   2255 C CA  . LYS B 2 91  ? -63.07502 15.46990  59.67166  1.000 79.62355  ? 87  LYS F CA  1 
ATOM   2256 C C   . LYS B 2 91  ? -63.46345 15.83375  58.24911  1.000 79.11520  ? 87  LYS F C   1 
ATOM   2257 O O   . LYS B 2 91  ? -63.63790 14.95392  57.39136  1.000 84.50295  ? 87  LYS F O   1 
ATOM   2258 C CB  . LYS B 2 91  ? -64.32012 15.52234  60.56603  1.000 85.81740  ? 87  LYS F CB  1 
ATOM   2259 C CG  . LYS B 2 91  ? -64.21049 14.99260  61.99007  1.000 75.82577  ? 87  LYS F CG  1 
ATOM   2260 C CD  . LYS B 2 91  ? -65.46654 15.39483  62.76885  1.000 79.17076  ? 87  LYS F CD  1 
ATOM   2261 C CE  . LYS B 2 91  ? -65.40387 15.03548  64.24340  1.000 87.45458  ? 87  LYS F CE  1 
ATOM   2262 N NZ  . LYS B 2 91  ? -64.34837 15.76918  64.97901  1.000 98.97998  ? 87  LYS F NZ  1 
ATOM   2263 N N   . ASN B 2 92  ? -63.62113 17.13144  57.98525  1.000 81.74024  ? 88  ASN F N   1 
ATOM   2264 C CA  A ASN B 2 92  ? -63.96409 17.57494  56.64245  0.559 83.29484  ? 88  ASN F CA  1 
ATOM   2265 C CA  B ASN B 2 92  ? -63.97842 17.53993  56.63569  0.441 83.11593  ? 88  ASN F CA  1 
ATOM   2266 C C   . ASN B 2 92  ? -62.84911 17.26075  55.65564  1.000 82.37795  ? 88  ASN F C   1 
ATOM   2267 O O   . ASN B 2 92  ? -63.11913 16.96062  54.49231  1.000 89.51715  ? 88  ASN F O   1 
ATOM   2268 C CB  A ASN B 2 92  ? -64.27829 19.07362  56.65630  0.559 83.26518  ? 88  ASN F CB  1 
ATOM   2269 C CB  B ASN B 2 92  ? -64.40429 19.01292  56.59984  0.441 83.38119  ? 88  ASN F CB  1 
ATOM   2270 C CG  A ASN B 2 92  ? -65.37728 19.43681  57.65247  0.559 81.87351  ? 88  ASN F CG  1 
ATOM   2271 C CG  B ASN B 2 92  ? -63.31408 19.96894  57.05042  0.441 80.26319  ? 88  ASN F CG  1 
ATOM   2272 O OD1 A ASN B 2 92  ? -66.08378 18.56818  58.16890  0.559 83.83876  ? 88  ASN F OD1 1 
ATOM   2273 O OD1 B ASN B 2 92  ? -62.19678 19.96395  56.53423  0.441 78.79851  ? 88  ASN F OD1 1 
ATOM   2274 N ND2 A ASN B 2 92  ? -65.51947 20.72771  57.92580  0.559 76.53124  ? 88  ASN F ND2 1 
ATOM   2275 N ND2 B ASN B 2 92  ? -63.65201 20.81824  58.01289  0.441 78.15892  ? 88  ASN F ND2 1 
ATOM   2276 N N   . ALA B 2 93  ? -61.58911 17.30252  56.10211  1.000 72.09859  ? 89  ALA F N   1 
ATOM   2277 C CA  . ALA B 2 93  ? -60.50850 16.93050  55.19773  1.000 73.96148  ? 89  ALA F CA  1 
ATOM   2278 C C   . ALA B 2 93  ? -60.57085 15.45005  54.84038  1.000 74.01341  ? 89  ALA F C   1 
ATOM   2279 O O   . ALA B 2 93  ? -60.36671 15.07610  53.67564  1.000 80.39965  ? 89  ALA F O   1 
ATOM   2280 C CB  . ALA B 2 93  ? -59.15797 17.27623  55.82077  1.000 69.77139  ? 89  ALA F CB  1 
ATOM   2281 N N   . VAL B 2 94  ? -60.94491 14.59918  55.79884  1.000 68.03653  ? 90  VAL F N   1 
ATOM   2282 C CA  . VAL B 2 94  ? -61.04485 13.17806  55.47346  1.000 72.12366  ? 90  VAL F CA  1 
ATOM   2283 C C   . VAL B 2 94  ? -62.22758 12.90689  54.54898  1.000 87.23768  ? 90  VAL F C   1 
ATOM   2284 O O   . VAL B 2 94  ? -62.10882 12.14163  53.58051  1.000 96.80848  ? 90  VAL F O   1 
ATOM   2285 C CB  . VAL B 2 94  ? -61.13121 12.33353  56.75625  1.000 76.15236  ? 90  VAL F CB  1 
ATOM   2286 C CG1 . VAL B 2 94  ? -61.35228 10.87110  56.40683  1.000 84.99621  ? 90  VAL F CG1 1 
ATOM   2287 C CG2 . VAL B 2 94  ? -59.86686 12.49252  57.57267  1.000 79.02199  ? 90  VAL F CG2 1 
ATOM   2288 N N   . THR B 2 95  ? -63.37568 13.54387  54.79949  1.000 86.66471  ? 91  THR F N   1 
ATOM   2289 C CA  . THR B 2 95  ? -64.51425 13.29501  53.91495  1.000 84.68595  ? 91  THR F CA  1 
ATOM   2290 C C   . THR B 2 95  ? -64.30356 13.90438  52.52898  1.000 93.43713  ? 91  THR F C   1 
ATOM   2291 O O   . THR B 2 95  ? -64.77390 13.34366  51.52506  1.000 105.03775 ? 91  THR F O   1 
ATOM   2292 C CB  . THR B 2 95  ? -65.80371 13.83027  54.53707  1.000 80.19745  ? 91  THR F CB  1 
ATOM   2293 O OG1 . THR B 2 95  ? -65.70031 15.24757  54.71708  1.000 78.55066  ? 91  THR F OG1 1 
ATOM   2294 C CG2 . THR B 2 95  ? -66.06201 13.15996  55.88659  1.000 84.02623  ? 91  THR F CG2 1 
ATOM   2295 N N   . ASP B 2 96  ? -63.58407 15.02973  52.44317  1.000 89.71231  ? 92  ASP F N   1 
ATOM   2296 C CA  . ASP B 2 96  ? -63.27855 15.61071  51.14120  1.000 90.94533  ? 92  ASP F CA  1 
ATOM   2297 C C   . ASP B 2 96  ? -62.34986 14.70427  50.34813  1.000 88.87462  ? 92  ASP F C   1 
ATOM   2298 O O   . ASP B 2 96  ? -62.56496 14.46926  49.15152  1.000 101.98233 ? 92  ASP F O   1 
ATOM   2299 C CB  . ASP B 2 96  ? -62.63796 16.99034  51.31690  1.000 89.76458  ? 92  ASP F CB  1 
ATOM   2300 C CG  . ASP B 2 96  ? -63.64288 18.06355  51.68099  1.000 100.66459 ? 92  ASP F CG  1 
ATOM   2301 O OD1 . ASP B 2 96  ? -64.82955 17.72917  51.87133  1.000 107.95329 ? 92  ASP F OD1 1 
ATOM   2302 O OD2 . ASP B 2 96  ? -63.24250 19.24283  51.78583  1.000 102.28175 ? 92  ASP F OD2 1 
ATOM   2303 N N   . LEU B 2 97  ? -61.36014 14.11432  51.02209  1.000 81.32632  ? 93  LEU F N   1 
ATOM   2304 C CA  . LEU B 2 97  ? -60.47936 13.17442  50.34495  1.000 82.90194  ? 93  LEU F CA  1 
ATOM   2305 C C   . LEU B 2 97  ? -61.19866 11.87977  49.97338  1.000 90.48588  ? 93  LEU F C   1 
ATOM   2306 O O   . LEU B 2 97  ? -60.76563 11.18902  49.04427  1.000 97.47657  ? 93  LEU F O   1 
ATOM   2307 C CB  . LEU B 2 97  ? -59.25014 12.93756  51.21187  1.000 81.61560  ? 93  LEU F CB  1 
ATOM   2308 C CG  . LEU B 2 97  ? -57.92124 12.80215  50.47454  1.000 77.48880  ? 93  LEU F CG  1 
ATOM   2309 C CD1 . LEU B 2 97  ? -57.72735 13.98148  49.55479  1.000 91.44981  ? 93  LEU F CD1 1 
ATOM   2310 C CD2 . LEU B 2 97  ? -56.79008 12.74086  51.47881  1.000 62.64249  ? 93  LEU F CD2 1 
ATOM   2311 N N   . GLN B 2 98  ? -62.28051 11.53372  50.67783  1.000 97.18441  ? 94  GLN F N   1 
ATOM   2312 C CA  . GLN B 2 98  ? -63.01597 10.31527  50.34235  1.000 109.75935 ? 94  GLN F CA  1 
ATOM   2313 C C   . GLN B 2 98  ? -63.85395 10.54391  49.08954  1.000 117.47068 ? 94  GLN F C   1 
ATOM   2314 O O   . GLN B 2 98  ? -63.85795 9.71076   48.16647  1.000 125.02774 ? 94  GLN F O   1 
ATOM   2315 C CB  . GLN B 2 98  ? -63.91376 9.86836   51.50112  1.000 106.21404 ? 94  GLN F CB  1 
ATOM   2316 C CG  . GLN B 2 98  ? -63.18711 9.25075   52.67844  1.000 90.31881  ? 94  GLN F CG  1 
ATOM   2317 C CD  . GLN B 2 98  ? -64.13195 8.88838   53.81343  1.000 100.41967 ? 94  GLN F CD  1 
ATOM   2318 O OE1 . GLN B 2 98  ? -65.21147 9.46976   53.94851  1.000 96.59409  ? 94  GLN F OE1 1 
ATOM   2319 N NE2 . GLN B 2 98  ? -63.73177 7.92324   54.63247  1.000 117.54236 ? 94  GLN F NE2 1 
ATOM   2320 N N   . LEU B 2 99  ? -64.52859 11.69742  49.02244  1.000 113.82815 ? 95  LEU F N   1 
ATOM   2321 C CA  . LEU B 2 99  ? -65.29262 12.00094  47.82189  1.000 125.21247 ? 95  LEU F CA  1 
ATOM   2322 C C   . LEU B 2 99  ? -64.35924 12.29752  46.65344  1.000 130.77265 ? 95  LEU F C   1 
ATOM   2323 O O   . LEU B 2 99  ? -64.77254 12.17619  45.48966  1.000 135.10281 ? 95  LEU F O   1 
ATOM   2324 C CB  . LEU B 2 99  ? -66.24107 13.18267  48.08163  1.000 122.32854 ? 95  LEU F CB  1 
ATOM   2325 C CG  . LEU B 2 99  ? -67.04688 13.76319  46.90972  1.000 138.05653 ? 95  LEU F CG  1 
ATOM   2326 C CD1 . LEU B 2 99  ? -68.27184 12.90389  46.59015  1.000 140.49013 ? 95  LEU F CD1 1 
ATOM   2327 C CD2 . LEU B 2 99  ? -67.45833 15.21294  47.17276  1.000 119.82175 ? 95  LEU F CD2 1 
ATOM   2328 N N   . LEU B 2 100 ? -63.07937 12.57658  46.93343  1.000 127.67085 ? 96  LEU F N   1 
ATOM   2329 C CA  . LEU B 2 100 ? -62.15583 12.74301  45.82353  1.000 120.00637 ? 96  LEU F CA  1 
ATOM   2330 C C   . LEU B 2 100 ? -61.85964 11.42446  45.12981  1.000 122.00357 ? 96  LEU F C   1 
ATOM   2331 O O   . LEU B 2 100 ? -61.65482 11.41547  43.91643  1.000 125.64424 ? 96  LEU F O   1 
ATOM   2332 C CB  . LEU B 2 100 ? -60.83974 13.35032  46.31781  1.000 112.10605 ? 96  LEU F CB  1 
ATOM   2333 C CG  . LEU B 2 100 ? -59.78805 13.52962  45.22864  1.000 105.86531 ? 96  LEU F CG  1 
ATOM   2334 C CD1 . LEU B 2 100 ? -60.23933 14.55018  44.18605  1.000 112.87238 ? 96  LEU F CD1 1 
ATOM   2335 C CD2 . LEU B 2 100 ? -58.42914 13.87367  45.82343  1.000 99.64533  ? 96  LEU F CD2 1 
ATOM   2336 N N   . MET B 2 101 ? -61.84933 10.30180  45.84792  1.000 121.17675 ? 97  MET F N   1 
ATOM   2337 C CA  . MET B 2 101 ? -61.58297 9.04910   45.15107  1.000 133.42500 ? 97  MET F CA  1 
ATOM   2338 C C   . MET B 2 101 ? -62.89157 8.44491   44.66827  1.000 141.93044 ? 97  MET F C   1 
ATOM   2339 O O   . MET B 2 101 ? -62.91492 7.65277   43.71363  1.000 139.47727 ? 97  MET F O   1 
ATOM   2340 C CB  . MET B 2 101 ? -60.84862 8.05578   46.05328  1.000 117.44546 ? 97  MET F CB  1 
ATOM   2341 C CG  . MET B 2 101 ? -60.19025 6.93920   45.25234  1.000 126.30647 ? 97  MET F CG  1 
ATOM   2342 S SD  . MET B 2 101 ? -59.45918 7.58973   43.72418  1.000 156.90566 ? 97  MET F SD  1 
ATOM   2343 C CE  . MET B 2 101 ? -59.98445 6.39928   42.49573  1.000 124.70281 ? 97  MET F CE  1 
ATOM   2344 N N   . GLN B 2 102 ? -63.98827 8.86565   45.29125  1.000 141.26560 ? 98  GLN F N   1 
ATOM   2345 C CA  . GLN B 2 102 ? -65.31767 8.53299   44.79388  1.000 138.40279 ? 98  GLN F CA  1 
ATOM   2346 C C   . GLN B 2 102 ? -65.58385 9.13310   43.40847  1.000 144.56415 ? 98  GLN F C   1 
ATOM   2347 O O   . GLN B 2 102 ? -66.19401 8.47210   42.55495  1.000 153.36509 ? 98  GLN F O   1 
ATOM   2348 C CB  . GLN B 2 102 ? -66.37370 8.90234   45.83560  1.000 136.63259 ? 98  GLN F CB  1 
ATOM   2349 C CG  . GLN B 2 102 ? -66.37029 7.83222   46.91523  1.000 129.11829 ? 98  GLN F CG  1 
ATOM   2350 C CD  . GLN B 2 102 ? -67.06995 8.24698   48.18138  1.000 127.42871 ? 98  GLN F CD  1 
ATOM   2351 O OE1 . GLN B 2 102 ? -67.51678 9.38431   48.32730  1.000 134.27930 ? 98  GLN F OE1 1 
ATOM   2352 N NE2 . GLN B 2 102 ? -67.19008 7.30843   49.10830  1.000 116.74938 ? 98  GLN F NE2 1 
ATOM   2353 N N   . SER B 2 103 ? -65.15631 10.38138  43.15459  1.000 143.61655 ? 99  SER F N   1 
ATOM   2354 C CA  . SER B 2 103 ? -65.38370 10.95821  41.81076  1.000 149.49620 ? 99  SER F CA  1 
ATOM   2355 C C   . SER B 2 103 ? -64.24949 11.73340  41.10735  1.000 149.14178 ? 99  SER F C   1 
ATOM   2356 O O   . SER B 2 103 ? -64.40835 12.89297  40.73309  1.000 147.22916 ? 99  SER F O   1 
ATOM   2357 C CB  . SER B 2 103 ? -66.59695 11.87891  41.91172  1.000 139.31462 ? 99  SER F CB  1 
ATOM   2358 O OG  . SER B 2 103 ? -67.69229 11.18897  42.47719  1.000 138.90450 ? 99  SER F OG  1 
ATOM   2359 N N   . THR B 2 104 ? -63.07058 11.09448  40.92387  1.000 144.42584 ? 100 THR F N   1 
ATOM   2360 C CA  . THR B 2 104 ? -61.89165 11.67015  40.25139  1.000 146.98967 ? 100 THR F CA  1 
ATOM   2361 C C   . THR B 2 104 ? -61.59473 10.99162  38.90160  1.000 163.84276 ? 100 THR F C   1 
ATOM   2362 O O   . THR B 2 104 ? -60.44496 10.59823  38.64248  1.000 171.39240 ? 100 THR F O   1 
ATOM   2363 C CB  . THR B 2 104 ? -60.65363 11.58153  41.12779  1.000 141.91502 ? 100 THR F CB  1 
ATOM   2364 O OG1 . THR B 2 104 ? -59.52500 12.07281  40.38945  1.000 145.58850 ? 100 THR F OG1 1 
ATOM   2365 C CG2 . THR B 2 104 ? -60.43839 10.12983  41.54739  1.000 137.69959 ? 100 THR F CG2 1 
ATOM   2366 N N   . PRO B 2 105 ? -62.58130 10.84484  38.01322  1.000 172.68165 ? 101 PRO F N   1 
ATOM   2367 C CA  . PRO B 2 105 ? -62.33228 10.16869  36.71941  1.000 175.39950 ? 101 PRO F CA  1 
ATOM   2368 C C   . PRO B 2 105 ? -61.41944 10.87680  35.73204  1.000 178.23933 ? 101 PRO F C   1 
ATOM   2369 O O   . PRO B 2 105 ? -60.86016 10.20225  34.85858  1.000 176.56686 ? 101 PRO F O   1 
ATOM   2370 C CB  . PRO B 2 105 ? -63.73409 10.07161  36.11150  1.000 159.20909 ? 101 PRO F CB  1 
ATOM   2371 C CG  . PRO B 2 105 ? -64.40025 11.21257  36.71734  1.000 158.27097 ? 101 PRO F CG  1 
ATOM   2372 C CD  . PRO B 2 105 ? -63.91898 11.44617  38.04844  1.000 162.39093 ? 101 PRO F CD  1 
ATOM   2373 N N   . ALA B 2 106 ? -61.27323 12.19615  35.79787  1.000 180.93117 ? 102 ALA F N   1 
ATOM   2374 C CA  . ALA B 2 106 ? -60.40178 12.88240  34.84918  1.000 180.33260 ? 102 ALA F CA  1 
ATOM   2375 C C   . ALA B 2 106 ? -58.92571 12.53066  35.02898  1.000 184.70358 ? 102 ALA F C   1 
ATOM   2376 O O   . ALA B 2 106 ? -58.44771 12.26370  36.13644  1.000 172.34400 ? 102 ALA F O   1 
ATOM   2377 C CB  . ALA B 2 106 ? -60.59892 14.39836  34.95136  1.000 169.03297 ? 102 ALA F CB  1 
ATOM   2378 N N   . THR B 2 107 ? -58.21471 12.51209  33.89723  1.000 189.85383 ? 103 THR F N   1 
ATOM   2379 C CA  . THR B 2 107 ? -56.79455 12.19142  33.81603  1.000 182.94503 ? 103 THR F CA  1 
ATOM   2380 C C   . THR B 2 107 ? -56.07683 13.40492  33.23619  1.000 181.31305 ? 103 THR F C   1 
ATOM   2381 O O   . THR B 2 107 ? -56.45821 13.90287  32.16998  1.000 182.78897 ? 103 THR F O   1 
ATOM   2382 C CB  . THR B 2 107 ? -56.54968 10.95785  32.93602  1.000 173.92868 ? 103 THR F CB  1 
ATOM   2383 O OG1 . THR B 2 107 ? -56.95883 9.77515   33.63373  1.000 179.52633 ? 103 THR F OG1 1 
ATOM   2384 C CG2 . THR B 2 107 ? -55.07454 10.83021  32.59633  1.000 154.56899 ? 103 THR F CG2 1 
ATOM   2385 N N   . GLY B 2 108 ? -55.04182 13.87439  33.94078  1.000 182.81141 ? 143 GLY F N   1 
ATOM   2386 C CA  . GLY B 2 108 ? -54.23792 14.98424  33.43842  1.000 183.38544 ? 143 GLY F CA  1 
ATOM   2387 C C   . GLY B 2 108 ? -53.35705 14.63007  32.25438  1.000 177.39881 ? 143 GLY F C   1 
ATOM   2388 O O   . GLY B 2 108 ? -53.36580 15.31777  31.22899  1.000 174.56436 ? 143 GLY F O   1 
ATOM   2389 N N   . SER B 2 109 ? -52.56189 13.57560  32.38733  1.000 164.18881 ? 144 SER F N   1 
ATOM   2390 C CA  . SER B 2 109 ? -51.68716 13.13635  31.30246  1.000 152.82860 ? 144 SER F CA  1 
ATOM   2391 C C   . SER B 2 109 ? -51.70775 11.61462  31.25445  1.000 146.02119 ? 144 SER F C   1 
ATOM   2392 O O   . SER B 2 109 ? -50.99921 10.95818  32.02434  1.000 136.15358 ? 144 SER F O   1 
ATOM   2393 C CB  . SER B 2 109 ? -50.27259 13.66396  31.50261  1.000 137.34409 ? 144 SER F CB  1 
ATOM   2394 O OG  . SER B 2 109 ? -49.39073 13.12883  30.53367  1.000 131.28787 ? 144 SER F OG  1 
ATOM   2395 N N   . GLY B 2 110 ? -52.52859 11.05917  30.36285  1.000 150.10419 ? 145 GLY F N   1 
ATOM   2396 C CA  . GLY B 2 110 ? -52.63574 9.61622   30.30445  1.000 149.79871 ? 145 GLY F CA  1 
ATOM   2397 C C   . GLY B 2 110 ? -51.34974 8.91401   29.92059  1.000 149.46241 ? 145 GLY F C   1 
ATOM   2398 O O   . GLY B 2 110 ? -51.10519 7.78699   30.35637  1.000 152.18831 ? 145 GLY F O   1 
ATOM   2399 N N   . SER B 2 111 ? -50.50460 9.55769   29.11276  1.000 139.43518 ? 146 SER F N   1 
ATOM   2400 C CA  . SER B 2 111 ? -49.24758 8.90285   28.77347  1.000 135.60755 ? 146 SER F CA  1 
ATOM   2401 C C   . SER B 2 111 ? -48.19756 8.92621   29.88483  1.000 132.49505 ? 146 SER F C   1 
ATOM   2402 O O   . SER B 2 111 ? -47.13749 8.30699   29.72107  1.000 132.94385 ? 146 SER F O   1 
ATOM   2403 C CB  . SER B 2 111 ? -48.65448 9.53322   27.51322  1.000 133.54974 ? 146 SER F CB  1 
ATOM   2404 O OG  . SER B 2 111 ? -48.48003 10.92323  27.68265  1.000 135.47219 ? 146 SER F OG  1 
ATOM   2405 N N   . ALA B 2 112 ? -48.41495 9.60527   31.01094  1.000 124.51980 ? 147 ALA F N   1 
ATOM   2406 C CA  . ALA B 2 112 ? -47.35204 9.57836   32.00229  1.000 119.21577 ? 147 ALA F CA  1 
ATOM   2407 C C   . ALA B 2 112 ? -47.76934 9.12003   33.38979  1.000 122.91512 ? 147 ALA F C   1 
ATOM   2408 O O   . ALA B 2 112 ? -46.90510 9.02766   34.27444  1.000 120.43703 ? 147 ALA F O   1 
ATOM   2409 C CB  . ALA B 2 112 ? -46.68176 10.95440  32.10168  1.000 112.15230 ? 147 ALA F CB  1 
ATOM   2410 N N   . ILE B 2 113 ? -49.05119 8.84776   33.62934  1.000 122.29538 ? 148 ILE F N   1 
ATOM   2411 C CA  . ILE B 2 113 ? -49.43978 8.42449   34.96284  1.000 116.64557 ? 148 ILE F CA  1 
ATOM   2412 C C   . ILE B 2 113 ? -50.03859 7.03133   34.94995  1.000 123.51727 ? 148 ILE F C   1 
ATOM   2413 O O   . ILE B 2 113 ? -50.61919 6.61187   35.94680  1.000 122.55281 ? 148 ILE F O   1 
ATOM   2414 C CB  . ILE B 2 113 ? -50.41206 9.43096   35.60962  1.000 102.89967 ? 148 ILE F CB  1 
ATOM   2415 C CG1 . ILE B 2 113 ? -51.71324 9.47862   34.82515  1.000 110.09271 ? 148 ILE F CG1 1 
ATOM   2416 C CG2 . ILE B 2 113 ? -49.75414 10.80534  35.70246  1.000 96.08072  ? 148 ILE F CG2 1 
ATOM   2417 C CD1 . ILE B 2 113 ? -52.71594 10.40874  35.39334  1.000 114.14173 ? 148 ILE F CD1 1 
ATOM   2418 N N   . CYS B 2 114 ? -49.88998 6.29698   33.83953  1.000 129.32041 ? 149 CYS F N   1 
ATOM   2419 C CA  . CYS B 2 114 ? -50.40849 4.93431   33.75414  1.000 139.51634 ? 149 CYS F CA  1 
ATOM   2420 C C   . CYS B 2 114 ? -49.75000 4.01080   34.77166  1.000 140.58207 ? 149 CYS F C   1 
ATOM   2421 O O   . CYS B 2 114 ? -50.42602 3.19765   35.41786  1.000 142.95032 ? 149 CYS F O   1 
ATOM   2422 C CB  . CYS B 2 114 ? -50.26038 4.41965   32.31664  1.000 143.62984 ? 149 CYS F CB  1 
ATOM   2423 S SG  . CYS B 2 114 ? -48.57802 4.16635   31.73664  1.000 162.05041 ? 149 CYS F SG  1 
ATOM   2424 N N   . SER B 2 115 ? -48.42872 4.12285   34.92743  1.000 132.76736 ? 150 SER F N   1 
ATOM   2425 C CA  A SER B 2 115 ? -47.70743 3.21716   35.81590  0.260 125.75029 ? 150 SER F CA  1 
ATOM   2426 C CA  B SER B 2 115 ? -47.70981 3.21544   35.81567  0.740 125.45648 ? 150 SER F CA  1 
ATOM   2427 C C   . SER B 2 115 ? -48.16404 3.37574   37.26043  1.000 118.78819 ? 150 SER F C   1 
ATOM   2428 O O   . SER B 2 115 ? -48.25258 2.39133   38.00228  1.000 123.18159 ? 150 SER F O   1 
ATOM   2429 C CB  A SER B 2 115 ? -46.20323 3.45864   35.69302  0.260 123.98096 ? 150 SER F CB  1 
ATOM   2430 C CB  B SER B 2 115 ? -46.20693 3.45396   35.69240  0.740 123.69373 ? 150 SER F CB  1 
ATOM   2431 O OG  A SER B 2 115 ? -45.88550 4.81474   35.94792  0.260 125.28347 ? 150 SER F OG  1 
ATOM   2432 O OG  B SER B 2 115 ? -45.89655 4.80759   35.96286  0.740 126.21744 ? 150 SER F OG  1 
ATOM   2433 N N   . GLY B 2 116 ? -48.46033 4.60819   37.67949  1.000 109.64834 ? 151 GLY F N   1 
ATOM   2434 C CA  . GLY B 2 116 ? -48.96698 4.81289   39.02495  1.000 116.88458 ? 151 GLY F CA  1 
ATOM   2435 C C   . GLY B 2 116 ? -50.44640 4.52264   39.16121  1.000 122.27002 ? 151 GLY F C   1 
ATOM   2436 O O   . GLY B 2 116 ? -50.89788 4.05111   40.21670  1.000 130.55059 ? 151 GLY F O   1 
ATOM   2437 N N   . VAL B 2 117 ? -51.22899 4.81389   38.11866  1.000 108.28319 ? 152 VAL F N   1 
ATOM   2438 C CA  . VAL B 2 117 ? -52.65157 4.51636   38.18871  1.000 111.80070 ? 152 VAL F CA  1 
ATOM   2439 C C   . VAL B 2 117 ? -52.86778 3.01771   38.32328  1.000 122.73454 ? 152 VAL F C   1 
ATOM   2440 O O   . VAL B 2 117 ? -53.80287 2.57874   39.00685  1.000 130.75196 ? 152 VAL F O   1 
ATOM   2441 C CB  . VAL B 2 117 ? -53.37993 5.10516   36.96532  1.000 111.61158 ? 152 VAL F CB  1 
ATOM   2442 C CG1 . VAL B 2 117 ? -54.77474 4.50942   36.82409  1.000 119.21467 ? 152 VAL F CG1 1 
ATOM   2443 C CG2 . VAL B 2 117 ? -53.45395 6.61940   37.09059  1.000 109.46653 ? 152 VAL F CG2 1 
ATOM   2444 N N   . ALA B 2 118 ? -52.01506 2.20338   37.68605  1.000 116.67542 ? 153 ALA F N   1 
ATOM   2445 C CA  . ALA B 2 118 ? -52.16956 0.76376   37.85877  1.000 113.83648 ? 153 ALA F CA  1 
ATOM   2446 C C   . ALA B 2 118 ? -51.93599 0.35862   39.30768  1.000 120.21426 ? 153 ALA F C   1 
ATOM   2447 O O   . ALA B 2 118 ? -52.61376 -0.54422  39.81702  1.000 125.76387 ? 153 ALA F O   1 
ATOM   2448 C CB  . ALA B 2 118 ? -51.20877 0.01097   36.93951  1.000 106.45695 ? 153 ALA F CB  1 
ATOM   2449 N N   . VAL B 2 119 ? -51.09173 1.10202   40.03003  1.000 122.84825 ? 154 VAL F N   1 
ATOM   2450 C CA  . VAL B 2 119 ? -50.85175 0.74149   41.42140  1.000 118.57599 ? 154 VAL F CA  1 
ATOM   2451 C C   . VAL B 2 119 ? -52.04423 1.15128   42.26769  1.000 114.44258 ? 154 VAL F C   1 
ATOM   2452 O O   . VAL B 2 119 ? -52.43915 0.43507   43.19751  1.000 116.24719 ? 154 VAL F O   1 
ATOM   2453 C CB  . VAL B 2 119 ? -49.54172 1.37599   41.93033  1.000 106.59271 ? 154 VAL F CB  1 
ATOM   2454 C CG1 . VAL B 2 119 ? -49.23668 0.90145   43.34035  1.000 105.54794 ? 154 VAL F CG1 1 
ATOM   2455 C CG2 . VAL B 2 119 ? -48.38025 1.04769   40.99896  1.000 108.23404 ? 154 VAL F CG2 1 
ATOM   2456 N N   . CYS B 2 120 ? -52.64380 2.30483   41.95571  1.000 109.46505 ? 155 CYS F N   1 
ATOM   2457 C CA  . CYS B 2 120 ? -53.82636 2.69124   42.71925  1.000 113.54565 ? 155 CYS F CA  1 
ATOM   2458 C C   . CYS B 2 120 ? -54.97567 1.72957   42.45071  1.000 114.23945 ? 155 CYS F C   1 
ATOM   2459 O O   . CYS B 2 120 ? -55.78682 1.46417   43.34587  1.000 114.71722 ? 155 CYS F O   1 
ATOM   2460 C CB  . CYS B 2 120 ? -54.24143 4.12580   42.41063  1.000 109.69818 ? 155 CYS F CB  1 
ATOM   2461 S SG  . CYS B 2 120 ? -53.18179 5.39835   43.16201  1.000 124.52030 ? 155 CYS F SG  1 
ATOM   2462 N N   . LYS B 2 121 ? -55.07186 1.21278   41.22134  1.000 110.99176 ? 156 LYS F N   1 
ATOM   2463 C CA  . LYS B 2 121 ? -56.12964 0.25540   40.92800  1.000 116.58824 ? 156 LYS F CA  1 
ATOM   2464 C C   . LYS B 2 121 ? -55.87851 -1.06897  41.63774  1.000 115.09495 ? 156 LYS F C   1 
ATOM   2465 O O   . LYS B 2 121 ? -56.83204 -1.77161  41.98967  1.000 119.52464 ? 156 LYS F O   1 
ATOM   2466 C CB  . LYS B 2 121 ? -56.25662 0.05545   39.41865  1.000 133.65233 ? 156 LYS F CB  1 
ATOM   2467 C CG  . LYS B 2 121 ? -57.50081 -0.71734  38.99770  1.000 144.12667 ? 156 LYS F CG  1 
ATOM   2468 C CD  . LYS B 2 121 ? -57.70721 -0.65894  37.48776  1.000 142.06949 ? 156 LYS F CD  1 
ATOM   2469 C CE  . LYS B 2 121 ? -58.97747 -1.38264  37.05722  1.000 135.26894 ? 156 LYS F CE  1 
ATOM   2470 N NZ  . LYS B 2 121 ? -59.19393 -1.29201  35.58488  1.000 124.35788 ? 156 LYS F NZ  1 
ATOM   2471 N N   . VAL B 2 122 ? -54.60777 -1.42219  41.86423  1.000 115.44065 ? 157 VAL F N   1 
ATOM   2472 C CA  . VAL B 2 122 ? -54.31636 -2.64751  42.60872  1.000 114.93411 ? 157 VAL F CA  1 
ATOM   2473 C C   . VAL B 2 122 ? -54.67674 -2.44786  44.07131  1.000 108.25147 ? 157 VAL F C   1 
ATOM   2474 O O   . VAL B 2 122 ? -55.20152 -3.35026  44.73521  1.000 109.55972 ? 157 VAL F O   1 
ATOM   2475 C CB  . VAL B 2 122 ? -52.84975 -3.08198  42.44392  1.000 116.10487 ? 157 VAL F CB  1 
ATOM   2476 C CG1 . VAL B 2 122 ? -52.60577 -4.36564  43.22408  1.000 114.00906 ? 157 VAL F CG1 1 
ATOM   2477 C CG2 . VAL B 2 122 ? -52.54264 -3.33189  40.98390  1.000 126.32122 ? 157 VAL F CG2 1 
ATOM   2478 N N   . LEU B 2 123 ? -54.39532 -1.25295  44.58796  1.000 103.63946 ? 158 LEU F N   1 
ATOM   2479 C CA  . LEU B 2 123 ? -54.68571 -0.91055  45.97421  1.000 102.98446 ? 158 LEU F CA  1 
ATOM   2480 C C   . LEU B 2 123 ? -56.18444 -0.87006  46.23996  1.000 109.17275 ? 158 LEU F C   1 
ATOM   2481 O O   . LEU B 2 123 ? -56.61731 -1.10097  47.37583  1.000 115.43922 ? 158 LEU F O   1 
ATOM   2482 C CB  . LEU B 2 123 ? -54.02641 0.41337   46.35011  1.000 100.26640 ? 158 LEU F CB  1 
ATOM   2483 C CG  . LEU B 2 123 ? -52.64302 0.15240   46.95046  1.000 98.22885  ? 158 LEU F CG  1 
ATOM   2484 C CD1 . LEU B 2 123 ? -51.94912 1.43158   47.41991  1.000 93.26996  ? 158 LEU F CD1 1 
ATOM   2485 C CD2 . LEU B 2 123 ? -52.75451 -0.87616  48.06776  1.000 104.15292 ? 158 LEU F CD2 1 
ATOM   2486 N N   . HIS B 2 124 ? -56.98977 -0.57645  45.21740  1.000 103.56833 ? 159 HIS F N   1 
ATOM   2487 C CA  . HIS B 2 124 ? -58.43000 -0.53501  45.41674  1.000 108.54133 ? 159 HIS F CA  1 
ATOM   2488 C C   . HIS B 2 124 ? -59.04011 -1.90263  45.68202  1.000 112.01789 ? 159 HIS F C   1 
ATOM   2489 O O   . HIS B 2 124 ? -60.19782 -1.95973  46.10952  1.000 116.16924 ? 159 HIS F O   1 
ATOM   2490 C CB  . HIS B 2 124 ? -59.09878 0.02840   44.16076  1.000 109.56153 ? 159 HIS F CB  1 
ATOM   2491 C CG  . HIS B 2 124 ? -59.45081 1.47711   44.24447  1.000 114.60676 ? 159 HIS F CG  1 
ATOM   2492 N ND1 . HIS B 2 124 ? -60.63732 1.92214   44.78652  1.000 119.44156 ? 159 HIS F ND1 1 
ATOM   2493 C CD2 . HIS B 2 124 ? -58.79063 2.58036   43.82205  1.000 113.05808 ? 159 HIS F CD2 1 
ATOM   2494 C CE1 . HIS B 2 124 ? -60.68542 3.23956   44.70989  1.000 123.40824 ? 159 HIS F CE1 1 
ATOM   2495 N NE2 . HIS B 2 124 ? -59.57703 3.66334   44.12936  1.000 120.85459 ? 159 HIS F NE2 1 
ATOM   2496 N N   . LEU B 2 125 ? -58.31487 -2.99383  45.44594  1.000 111.08873 ? 160 LEU F N   1 
ATOM   2497 C CA  . LEU B 2 125 ? -58.84298 -4.30470  45.79390  1.000 114.72769 ? 160 LEU F CA  1 
ATOM   2498 C C   . LEU B 2 125 ? -58.91560 -4.49016  47.30795  1.000 126.18333 ? 160 LEU F C   1 
ATOM   2499 O O   . LEU B 2 125 ? -58.11005 -3.94405  48.06817  1.000 123.87541 ? 160 LEU F O   1 
ATOM   2500 C CB  . LEU B 2 125 ? -57.97843 -5.41669  45.19992  1.000 116.57824 ? 160 LEU F CB  1 
ATOM   2501 C CG  . LEU B 2 125 ? -57.78747 -5.45819  43.68767  1.000 120.88687 ? 160 LEU F CG  1 
ATOM   2502 C CD1 . LEU B 2 125 ? -56.92257 -6.64920  43.29419  1.000 111.74039 ? 160 LEU F CD1 1 
ATOM   2503 C CD2 . LEU B 2 125 ? -59.13939 -5.51098  43.00144  1.000 129.14232 ? 160 LEU F CD2 1 
ATOM   2504 N N   . GLU B 2 126 ? -59.88928 -5.28810  47.73529  1.000 137.89485 ? 161 GLU F N   1 
ATOM   2505 C CA  . GLU B 2 126 ? -60.09369 -5.57683  49.15031  1.000 133.82191 ? 161 GLU F CA  1 
ATOM   2506 C C   . GLU B 2 126 ? -59.01114 -6.51976  49.66173  1.000 108.82626 ? 161 GLU F C   1 
ATOM   2507 O O   . GLU B 2 126 ? -58.75796 -7.57276  49.06982  1.000 99.37673  ? 161 GLU F O   1 
ATOM   2508 C CB  . GLU B 2 126 ? -61.49678 -6.12703  49.39892  1.000 141.84372 ? 161 GLU F CB  1 
ATOM   2509 C CG  . GLU B 2 126 ? -62.58141 -5.04263  49.32444  1.000 142.89143 ? 161 GLU F CG  1 
ATOM   2510 C CD  . GLU B 2 126 ? -62.93793 -4.61836  47.90826  1.000 148.52956 ? 161 GLU F CD  1 
ATOM   2511 O OE1 . GLU B 2 126 ? -62.35082 -5.16158  46.94670  1.000 149.17003 ? 161 GLU F OE1 1 
ATOM   2512 O OE2 . GLU B 2 126 ? -63.80349 -3.72608  47.76147  1.000 145.89460 ? 161 GLU F OE2 1 
ATOM   2513 N N   . GLY B 2 127 ? -58.36164 -6.13351  50.75124  1.000 100.55691 ? 162 GLY F N   1 
ATOM   2514 C CA  . GLY B 2 127 ? -57.30763 -6.92446  51.34387  1.000 105.08026 ? 162 GLY F CA  1 
ATOM   2515 C C   . GLY B 2 127 ? -55.91049 -6.50612  50.94956  1.000 100.72946 ? 162 GLY F C   1 
ATOM   2516 O O   . GLY B 2 127 ? -54.94686 -6.96969  51.57180  1.000 99.00720  ? 162 GLY F O   1 
ATOM   2517 N N   . GLU B 2 128 ? -55.76616 -5.66367  49.92739  1.000 96.13563  ? 163 GLU F N   1 
ATOM   2518 C CA  . GLU B 2 128 ? -54.43231 -5.26009  49.50748  1.000 97.38949  ? 163 GLU F CA  1 
ATOM   2519 C C   . GLU B 2 128 ? -53.94477 -4.15414  50.43220  1.000 98.36011  ? 163 GLU F C   1 
ATOM   2520 O O   . GLU B 2 128 ? -52.77068 -4.13270  50.84975  1.000 93.55223  ? 163 GLU F O   1 
ATOM   2521 C CB  . GLU B 2 128 ? -54.45924 -4.77389  48.05520  1.000 100.14240 ? 163 GLU F CB  1 
ATOM   2522 C CG  . GLU B 2 128 ? -54.25382 -5.84074  46.98358  1.000 111.01009 ? 163 GLU F CG  1 
ATOM   2523 C CD  . GLU B 2 128 ? -53.01436 -6.68830  47.20338  1.000 119.30765 ? 163 GLU F CD  1 
ATOM   2524 O OE1 . GLU B 2 128 ? -51.89281 -6.18109  46.98580  1.000 118.15257 ? 163 GLU F OE1 1 
ATOM   2525 O OE2 . GLU B 2 128 ? -53.16202 -7.86588  47.59514  1.000 128.50202 ? 163 GLU F OE2 1 
ATOM   2526 N N   . VAL B 2 129 ? -54.86334 -3.25002  50.79266  1.000 97.59758  ? 164 VAL F N   1 
ATOM   2527 C CA  . VAL B 2 129 ? -54.51649 -2.23460  51.76827  1.000 93.70382  ? 164 VAL F CA  1 
ATOM   2528 C C   . VAL B 2 129 ? -54.25238 -2.88475  53.11834  1.000 80.92586  ? 164 VAL F C   1 
ATOM   2529 O O   . VAL B 2 129 ? -53.39329 -2.42271  53.87166  1.000 74.95026  ? 164 VAL F O   1 
ATOM   2530 C CB  . VAL B 2 129 ? -55.65360 -1.19482  51.85837  1.000 90.93371  ? 164 VAL F CB  1 
ATOM   2531 C CG1 . VAL B 2 129 ? -55.17006 0.09223   52.51881  1.000 85.36830  ? 164 VAL F CG1 1 
ATOM   2532 C CG2 . VAL B 2 129 ? -56.27720 -0.92984  50.48578  1.000 83.63692  ? 164 VAL F CG2 1 
ATOM   2533 N N   . ASN B 2 130 ? -54.89674 -4.02306  53.40447  1.000 81.98526  ? 165 ASN F N   1 
ATOM   2534 C CA  . ASN B 2 130 ? -54.60767 -4.72928  54.64934  1.000 83.61872  ? 165 ASN F CA  1 
ATOM   2535 C C   . ASN B 2 130 ? -53.20411 -5.30793  54.60847  1.000 80.78139  ? 165 ASN F C   1 
ATOM   2536 O O   . ASN B 2 130 ? -52.51899 -5.37902  55.63750  1.000 88.85493  ? 165 ASN F O   1 
ATOM   2537 C CB  . ASN B 2 130 ? -55.66799 -5.79795  54.90150  1.000 87.28391  ? 165 ASN F CB  1 
ATOM   2538 C CG  . ASN B 2 130 ? -57.07465 -5.22148  54.89000  1.000 93.46564  ? 165 ASN F CG  1 
ATOM   2539 O OD1 . ASN B 2 130 ? -57.62585 -4.91661  53.82827  1.000 99.04736  ? 165 ASN F OD1 1 
ATOM   2540 N ND2 . ASN B 2 130 ? -57.66440 -5.07317  56.07037  1.000 86.68026  ? 165 ASN F ND2 1 
ATOM   2541 N N   . LYS B 2 131 ? -52.71444 -5.58027  53.40020  1.000 74.83644  ? 166 LYS F N   1 
ATOM   2542 C CA  . LYS B 2 131 ? -51.38954 -6.15227  53.24912  1.000 82.04088  ? 166 LYS F CA  1 
ATOM   2543 C C   . LYS B 2 131 ? -50.34495 -5.09244  53.54353  1.000 79.10749  ? 166 LYS F C   1 
ATOM   2544 O O   . LYS B 2 131 ? -49.43576 -5.30889  54.35828  1.000 81.34306  ? 166 LYS F O   1 
ATOM   2545 C CB  . LYS B 2 131 ? -51.21649 -6.71125  51.83369  1.000 88.92818  ? 166 LYS F CB  1 
ATOM   2546 C CG  . LYS B 2 131 ? -49.85092 -7.33423  51.57528  1.000 94.31730  ? 166 LYS F CG  1 
ATOM   2547 C CD  . LYS B 2 131 ? -49.67924 -7.81417  50.13135  1.000 101.30576 ? 166 LYS F CD  1 
ATOM   2548 C CE  . LYS B 2 131 ? -50.70398 -8.86805  49.72897  1.000 111.15975 ? 166 LYS F CE  1 
ATOM   2549 N NZ  . LYS B 2 131 ? -50.51317 -9.30942  48.31109  1.000 113.55442 ? 166 LYS F NZ  1 
ATOM   2550 N N   . ILE B 2 132 ? -50.44858 -3.93839  52.87913  1.000 81.63345  ? 167 ILE F N   1 
ATOM   2551 C CA  . ILE B 2 132 ? -49.48023 -2.89612  53.19975  1.000 91.11662  ? 167 ILE F CA  1 
ATOM   2552 C C   . ILE B 2 132 ? -49.62826 -2.43400  54.65118  1.000 83.52844  ? 167 ILE F C   1 
ATOM   2553 O O   . ILE B 2 132 ? -48.63109 -2.07213  55.28611  1.000 84.99793  ? 167 ILE F O   1 
ATOM   2554 C CB  . ILE B 2 132 ? -49.58257 -1.70822  52.21842  1.000 95.56371  ? 167 ILE F CB  1 
ATOM   2555 C CG1 . ILE B 2 132 ? -51.01281 -1.19644  52.11667  1.000 95.99969  ? 167 ILE F CG1 1 
ATOM   2556 C CG2 . ILE B 2 132 ? -49.04372 -2.08122  50.83716  1.000 93.29152  ? 167 ILE F CG2 1 
ATOM   2557 C CD1 . ILE B 2 132 ? -51.16935 -0.10485  51.09854  1.000 91.14941  ? 167 ILE F CD1 1 
ATOM   2558 N N   . LYS B 2 133 ? -50.84510 -2.47416  55.22050  1.000 79.82392  ? 168 LYS F N   1 
ATOM   2559 C CA  . LYS B 2 133 ? -51.00517 -2.09636  56.62729  1.000 88.38554  ? 168 LYS F CA  1 
ATOM   2560 C C   . LYS B 2 133 ? -50.31370 -3.07799  57.55582  1.000 88.48476  ? 168 LYS F C   1 
ATOM   2561 O O   . LYS B 2 133 ? -49.91100 -2.70549  58.66428  1.000 89.25828  ? 168 LYS F O   1 
ATOM   2562 C CB  . LYS B 2 133 ? -52.47644 -1.99184  57.03351  1.000 93.21532  ? 168 LYS F CB  1 
ATOM   2563 C CG  . LYS B 2 133 ? -53.27362 -0.87284  56.40128  1.000 98.76473  ? 168 LYS F CG  1 
ATOM   2564 C CD  . LYS B 2 133 ? -54.72686 -0.97322  56.82744  1.000 94.66615  ? 168 LYS F CD  1 
ATOM   2565 C CE  . LYS B 2 133 ? -54.83196 -0.93415  58.34421  1.000 78.15576  ? 168 LYS F CE  1 
ATOM   2566 N NZ  . LYS B 2 133 ? -56.24511 -1.00239  58.78960  1.000 80.66830  ? 168 LYS F NZ  1 
ATOM   2567 N N   . SER B 2 134 ? -50.16430 -4.32763  57.12193  1.000 88.46012  ? 169 SER F N   1 
ATOM   2568 C CA  . SER B 2 134 ? -49.47758 -5.29884  57.95993  1.000 87.40378  ? 169 SER F CA  1 
ATOM   2569 C C   . SER B 2 134 ? -47.96344 -5.22057  57.79422  1.000 88.34935  ? 169 SER F C   1 
ATOM   2570 O O   . SER B 2 134 ? -47.22769 -5.36251  58.77665  1.000 87.54173  ? 169 SER F O   1 
ATOM   2571 C CB  . SER B 2 134 ? -49.98497 -6.70829  57.64461  1.000 87.03233  ? 169 SER F CB  1 
ATOM   2572 O OG  . SER B 2 134 ? -51.38866 -6.80265  57.82554  1.000 86.33201  ? 169 SER F OG  1 
ATOM   2573 N N   . ALA B 2 135 ? -47.47029 -4.98722  56.57619  1.000 91.27774  ? 170 ALA F N   1 
ATOM   2574 C CA  . ALA B 2 135 ? -46.01883 -4.94832  56.39974  1.000 93.98209  ? 170 ALA F CA  1 
ATOM   2575 C C   . ALA B 2 135 ? -45.36238 -3.73589  57.07349  1.000 96.31237  ? 170 ALA F C   1 
ATOM   2576 O O   . ALA B 2 135 ? -44.24617 -3.84994  57.59322  1.000 98.81130  ? 170 ALA F O   1 
ATOM   2577 C CB  . ALA B 2 135 ? -45.68066 -4.98375  54.91057  1.000 88.11466  ? 170 ALA F CB  1 
ATOM   2578 N N   . LEU B 2 136 ? -46.01925 -2.57214  57.08001  1.000 91.89056  ? 171 LEU F N   1 
ATOM   2579 C CA  . LEU B 2 136 ? -45.48870 -1.36203  57.73536  1.000 95.43620  ? 171 LEU F CA  1 
ATOM   2580 C C   . LEU B 2 136 ? -45.95077 -1.18947  59.18707  1.000 98.86691  ? 171 LEU F C   1 
ATOM   2581 O O   . LEU B 2 136 ? -46.15848 -0.06806  59.66134  1.000 97.18022  ? 171 LEU F O   1 
ATOM   2582 C CB  . LEU B 2 136 ? -45.78137 -0.11490  56.90132  1.000 97.54832  ? 171 LEU F CB  1 
ATOM   2583 C CG  . LEU B 2 136 ? -47.15300 0.34659   56.40893  1.000 107.10406 ? 171 LEU F CG  1 
ATOM   2584 C CD1 . LEU B 2 136 ? -47.96999 1.08172   57.47712  1.000 112.47697 ? 171 LEU F CD1 1 
ATOM   2585 C CD2 . LEU B 2 136 ? -46.97678 1.21271   55.17018  1.000 94.95330  ? 171 LEU F CD2 1 
ATOM   2586 N N   . LEU B 2 137 ? -46.07747 -2.28833  59.92827  1.000 101.01389 ? 172 LEU F N   1 
ATOM   2587 C CA  . LEU B 2 137 ? -46.53228 -2.27469  61.31870  1.000 99.88745  ? 172 LEU F CA  1 
ATOM   2588 C C   . LEU B 2 137 ? -45.44120 -1.86947  62.30562  1.000 96.16956  ? 172 LEU F C   1 
ATOM   2589 O O   . LEU B 2 137 ? -45.75041 -1.29552  63.35566  1.000 98.88884  ? 172 LEU F O   1 
ATOM   2590 C CB  . LEU B 2 137 ? -47.09972 -3.63852  61.71083  1.000 99.29648  ? 172 LEU F CB  1 
ATOM   2591 C CG  . LEU B 2 137 ? -48.60697 -3.77063  61.49275  1.000 95.91185  ? 172 LEU F CG  1 
ATOM   2592 C CD1 . LEU B 2 137 ? -49.17184 -4.96003  62.25449  1.000 89.03153  ? 172 LEU F CD1 1 
ATOM   2593 C CD2 . LEU B 2 137 ? -49.31257 -2.48436  61.89589  1.000 91.31983  ? 172 LEU F CD2 1 
ATOM   2594 N N   . SER B 2 138 ? -44.17570 -2.14528  62.00392  1.000 97.63671  ? 173 SER F N   1 
ATOM   2595 C CA  . SER B 2 138 ? -43.08668 -1.90310  62.93855  1.000 102.79037 ? 173 SER F CA  1 
ATOM   2596 C C   . SER B 2 138 ? -42.07996 -0.87184  62.45681  1.000 106.98451 ? 173 SER F C   1 
ATOM   2597 O O   . SER B 2 138 ? -41.38243 -0.28752  63.29427  1.000 104.92011 ? 173 SER F O   1 
ATOM   2598 C CB  . SER B 2 138 ? -42.34016 -3.21062  63.24828  1.000 102.36485 ? 173 SER F CB  1 
ATOM   2599 O OG  . SER B 2 138 ? -41.92612 -3.86421  62.05997  1.000 103.80932 ? 173 SER F OG  1 
ATOM   2600 N N   . THR B 2 139 ? -41.97569 -0.63185  61.15547  1.000 110.65326 ? 174 THR F N   1 
ATOM   2601 C CA  . THR B 2 139 ? -40.97790 0.27065   60.60830  1.000 118.36246 ? 174 THR F CA  1 
ATOM   2602 C C   . THR B 2 139 ? -41.68193 1.35957   59.80892  1.000 113.65210 ? 174 THR F C   1 
ATOM   2603 O O   . THR B 2 139 ? -42.87576 1.27488   59.51124  1.000 105.68669 ? 174 THR F O   1 
ATOM   2604 C CB  . THR B 2 139 ? -39.98312 -0.47563  59.71118  1.000 117.12618 ? 174 THR F CB  1 
ATOM   2605 O OG1 . THR B 2 139 ? -40.69929 -1.16590  58.67775  1.000 105.80048 ? 174 THR F OG1 1 
ATOM   2606 C CG2 . THR B 2 139 ? -39.18149 -1.47886  60.52806  1.000 110.20605 ? 174 THR F CG2 1 
ATOM   2607 N N   . ASN B 2 140 ? -40.92393 2.39767   59.45791  1.000 114.57525 ? 175 ASN F N   1 
ATOM   2608 C CA  . ASN B 2 140 ? -41.48364 3.46544   58.63906  1.000 111.27892 ? 175 ASN F CA  1 
ATOM   2609 C C   . ASN B 2 140 ? -41.51150 3.06303   57.17372  1.000 111.45369 ? 175 ASN F C   1 
ATOM   2610 O O   . ASN B 2 140 ? -42.47117 3.36705   56.45766  1.000 108.48146 ? 175 ASN F O   1 
ATOM   2611 C CB  . ASN B 2 140 ? -40.66964 4.74807   58.81698  1.000 112.66072 ? 175 ASN F CB  1 
ATOM   2612 C CG  . ASN B 2 140 ? -40.65386 5.22888   60.25015  1.000 132.12735 ? 175 ASN F CG  1 
ATOM   2613 O OD1 . ASN B 2 140 ? -41.59585 4.98938   61.00391  1.000 141.13816 ? 175 ASN F OD1 1 
ATOM   2614 N ND2 . ASN B 2 140 ? -39.58758 5.92627   60.63278  1.000 138.78058 ? 175 ASN F ND2 1 
ATOM   2615 N N   . LYS B 2 141 ? -40.47113 2.37706   56.72454  1.000 111.36884 ? 176 LYS F N   1 
ATOM   2616 C CA  . LYS B 2 141 ? -40.32090 1.93411   55.35187  1.000 106.05271 ? 176 LYS F CA  1 
ATOM   2617 C C   . LYS B 2 141 ? -40.37026 0.41150   55.29189  1.000 104.34484 ? 176 LYS F C   1 
ATOM   2618 O O   . LYS B 2 141 ? -39.93557 -0.27450  56.22235  1.000 107.20652 ? 176 LYS F O   1 
ATOM   2619 C CB  . LYS B 2 141 ? -39.02149 2.51970   54.78529  1.000 109.71584 ? 176 LYS F CB  1 
ATOM   2620 C CG  . LYS B 2 141 ? -37.73538 1.92120   55.34686  1.000 114.11997 ? 176 LYS F CG  1 
ATOM   2621 C CD  . LYS B 2 141 ? -36.52960 2.71565   54.84532  1.000 110.25303 ? 176 LYS F CD  1 
ATOM   2622 C CE  . LYS B 2 141 ? -35.20726 2.17293   55.37060  1.000 111.27457 ? 176 LYS F CE  1 
ATOM   2623 N NZ  . LYS B 2 141 ? -34.90272 0.79348   54.92825  1.000 108.61296 ? 176 LYS F NZ  1 
ATOM   2624 N N   . ALA B 2 142 ? -40.90872 -0.11140  54.18756  1.000 101.73873 ? 177 ALA F N   1 
ATOM   2625 C CA  . ALA B 2 142 ? -41.02243 -1.55222  53.99392  1.000 102.92037 ? 177 ALA F CA  1 
ATOM   2626 C C   . ALA B 2 142 ? -41.41308 -1.85469  52.55236  1.000 98.54858  ? 177 ALA F C   1 
ATOM   2627 O O   . ALA B 2 142 ? -42.20825 -1.12935  51.95155  1.000 104.71629 ? 177 ALA F O   1 
ATOM   2628 C CB  . ALA B 2 142 ? -42.05107 -2.16474  54.95461  1.000 109.15109 ? 177 ALA F CB  1 
ATOM   2629 N N   . VAL B 2 143 ? -40.83938 -2.92673  52.01590  1.000 99.02268  ? 178 VAL F N   1 
ATOM   2630 C CA  . VAL B 2 143 ? -41.12692 -3.46569  50.68808  1.000 103.51140 ? 178 VAL F CA  1 
ATOM   2631 C C   . VAL B 2 143 ? -42.32315 -4.40820  50.74665  1.000 100.00784 ? 178 VAL F C   1 
ATOM   2632 O O   . VAL B 2 143 ? -42.43517 -5.23434  51.66044  1.000 106.19012 ? 178 VAL F O   1 
ATOM   2633 C CB  . VAL B 2 143 ? -39.89153 -4.18027  50.11466  1.000 109.54921 ? 178 VAL F CB  1 
ATOM   2634 C CG1 . VAL B 2 143 ? -40.22070 -4.81617  48.76576  1.000 107.16297 ? 178 VAL F CG1 1 
ATOM   2635 C CG2 . VAL B 2 143 ? -38.72302 -3.20608  50.00594  1.000 109.29250 ? 178 VAL F CG2 1 
ATOM   2636 N N   . VAL B 2 144 ? -43.22381 -4.28869  49.77075  1.000 95.88814  ? 179 VAL F N   1 
ATOM   2637 C CA  . VAL B 2 144 ? -44.44510 -5.08415  49.71732  1.000 102.13241 ? 179 VAL F CA  1 
ATOM   2638 C C   . VAL B 2 144 ? -44.56846 -5.71563  48.33940  1.000 106.01901 ? 179 VAL F C   1 
ATOM   2639 O O   . VAL B 2 144 ? -44.50841 -5.01945  47.32034  1.000 110.06235 ? 179 VAL F O   1 
ATOM   2640 C CB  . VAL B 2 144 ? -45.69827 -4.23988  50.01237  1.000 104.55214 ? 179 VAL F CB  1 
ATOM   2641 C CG1 . VAL B 2 144 ? -46.94904 -5.10183  49.89343  1.000 105.20525 ? 179 VAL F CG1 1 
ATOM   2642 C CG2 . VAL B 2 144 ? -45.60690 -3.61423  51.39090  1.000 112.53045 ? 179 VAL F CG2 1 
ATOM   2643 N N   . SER B 2 145 ? -44.74969 -7.03316  48.31781  1.000 112.06286 ? 180 SER F N   1 
ATOM   2644 C CA  . SER B 2 145 ? -45.00501 -7.78633  47.09641  1.000 107.35856 ? 180 SER F CA  1 
ATOM   2645 C C   . SER B 2 145 ? -46.51235 -7.85549  46.88342  1.000 106.82705 ? 180 SER F C   1 
ATOM   2646 O O   . SER B 2 145 ? -47.22921 -8.52864  47.62881  1.000 111.98302 ? 180 SER F O   1 
ATOM   2647 C CB  . SER B 2 145 ? -44.38507 -9.17861  47.16810  1.000 106.84612 ? 180 SER F CB  1 
ATOM   2648 O OG  . SER B 2 145 ? -44.87702 -9.88476  48.28869  1.000 132.40607 ? 180 SER F OG  1 
ATOM   2649 N N   . LEU B 2 146 ? -46.98436 -7.16430  45.85945  1.000 103.98623 ? 181 LEU F N   1 
ATOM   2650 C CA  . LEU B 2 146 ? -48.39206 -7.07116  45.52437  1.000 107.65270 ? 181 LEU F CA  1 
ATOM   2651 C C   . LEU B 2 146 ? -48.81238 -8.36830  44.84676  1.000 114.48188 ? 181 LEU F C   1 
ATOM   2652 O O   . LEU B 2 146 ? -48.00512 -9.27566  44.63724  1.000 118.10441 ? 181 LEU F O   1 
ATOM   2653 C CB  . LEU B 2 146 ? -48.64716 -5.84882  44.64850  1.000 115.41621 ? 181 LEU F CB  1 
ATOM   2654 C CG  . LEU B 2 146 ? -48.94803 -4.55459  45.41860  1.000 113.23391 ? 181 LEU F CG  1 
ATOM   2655 C CD1 . LEU B 2 146 ? -47.85421 -4.19001  46.42879  1.000 98.77559  ? 181 LEU F CD1 1 
ATOM   2656 C CD2 . LEU B 2 146 ? -49.19976 -3.40483  44.44918  1.000 118.43513 ? 181 LEU F CD2 1 
ATOM   2657 N N   . SER B 2 147 ? -50.08576 -8.47957  44.48843  1.000 114.79512 ? 182 SER F N   1 
ATOM   2658 C CA  . SER B 2 147 ? -50.49627 -9.72306  43.85242  1.000 127.20247 ? 182 SER F CA  1 
ATOM   2659 C C   . SER B 2 147 ? -50.22680 -9.71221  42.36113  1.000 131.06082 ? 182 SER F C   1 
ATOM   2660 O O   . SER B 2 147 ? -50.20131 -10.78129 41.74273  1.000 137.85018 ? 182 SER F O   1 
ATOM   2661 C CB  . SER B 2 147 ? -51.98400 -9.97380  44.07919  1.000 133.15431 ? 182 SER F CB  1 
ATOM   2662 O OG  . SER B 2 147 ? -52.30713 -9.85272  45.45072  1.000 134.15317 ? 182 SER F OG  1 
ATOM   2663 N N   . ASN B 2 148 ? -50.02111 -8.54155  41.76707  1.000 127.47483 ? 183 ASN F N   1 
ATOM   2664 C CA  . ASN B 2 148 ? -49.68227 -8.46985  40.35860  1.000 128.06708 ? 183 ASN F CA  1 
ATOM   2665 C C   . ASN B 2 148 ? -48.18266 -8.48196  40.14123  1.000 130.73976 ? 183 ASN F C   1 
ATOM   2666 O O   . ASN B 2 148 ? -47.73000 -8.20711  39.02429  1.000 137.52994 ? 183 ASN F O   1 
ATOM   2667 C CB  . ASN B 2 148 ? -50.27611 -7.21683  39.72955  1.000 126.16643 ? 183 ASN F CB  1 
ATOM   2668 C CG  . ASN B 2 148 ? -49.69949 -5.93547  40.30372  1.000 130.00939 ? 183 ASN F CG  1 
ATOM   2669 O OD1 . ASN B 2 148 ? -49.29273 -5.88010  41.46845  1.000 129.14889 ? 183 ASN F OD1 1 
ATOM   2670 N ND2 . ASN B 2 148 ? -49.70159 -4.88645  39.49940  1.000 132.29509 ? 183 ASN F ND2 1 
ATOM   2671 N N   . GLY B 2 149 ? -47.42805 -8.84296  41.17997  1.000 120.46946 ? 184 GLY F N   1 
ATOM   2672 C CA  . GLY B 2 149 ? -45.98831 -8.96165  41.19017  1.000 120.25821 ? 184 GLY F CA  1 
ATOM   2673 C C   . GLY B 2 149 ? -45.03929 -7.79295  41.45011  1.000 122.42604 ? 184 GLY F C   1 
ATOM   2674 O O   . GLY B 2 149 ? -43.91818 -8.05851  41.89412  1.000 120.67797 ? 184 GLY F O   1 
ATOM   2675 N N   . PRO B 2 150 ? -45.38457 -6.51884  41.19949  1.000 122.50768 ? 185 PRO F N   1 
ATOM   2676 C CA  . PRO B 2 150 ? -44.40733 -5.45987  41.50503  1.000 114.26525 ? 185 PRO F CA  1 
ATOM   2677 C C   . PRO B 2 150 ? -44.06121 -5.37891  42.98755  1.000 107.38836 ? 185 PRO F C   1 
ATOM   2678 O O   . PRO B 2 150 ? -44.92268 -5.51038  43.85903  1.000 105.00758 ? 185 PRO F O   1 
ATOM   2679 C CB  . PRO B 2 150 ? -45.09339 -4.18348  41.00293  1.000 114.24931 ? 185 PRO F CB  1 
ATOM   2680 C CG  . PRO B 2 150 ? -45.92652 -4.65358  39.88176  1.000 116.61781 ? 185 PRO F CG  1 
ATOM   2681 C CD  . PRO B 2 150 ? -46.44683 -5.98120  40.32907  1.000 117.69491 ? 185 PRO F CD  1 
ATOM   2682 N N   . SER B 2 151 ? -42.77044 -5.17784  43.25042  1.000 105.14536 ? 186 SER F N   1 
ATOM   2683 C CA  . SER B 2 151 ? -42.21696 -5.04717  44.59084  1.000 110.83272 ? 186 SER F CA  1 
ATOM   2684 C C   . SER B 2 151 ? -42.08627 -3.55743  44.88117  1.000 116.19787 ? 186 SER F C   1 
ATOM   2685 O O   . SER B 2 151 ? -41.02870 -2.95760  44.66823  1.000 120.66913 ? 186 SER F O   1 
ATOM   2686 C CB  . SER B 2 151 ? -40.86793 -5.75153  44.70624  1.000 103.56917 ? 186 SER F CB  1 
ATOM   2687 O OG  . SER B 2 151 ? -39.97107 -5.33398  43.68620  1.000 100.97080 ? 186 SER F OG  1 
ATOM   2688 N N   . VAL B 2 152 ? -43.15728 -2.95932  45.39604  1.000 115.07376 ? 187 VAL F N   1 
ATOM   2689 C CA  . VAL B 2 152 ? -43.19079 -1.51242  45.58757  1.000 106.35700 ? 187 VAL F CA  1 
ATOM   2690 C C   . VAL B 2 152 ? -42.72656 -1.21498  47.00081  1.000 106.93620 ? 187 VAL F C   1 
ATOM   2691 O O   . VAL B 2 152 ? -42.80350 -2.06841  47.89188  1.000 109.71355 ? 187 VAL F O   1 
ATOM   2692 C CB  . VAL B 2 152 ? -44.59997 -0.93592  45.33097  1.000 94.49283  ? 187 VAL F CB  1 
ATOM   2693 C CG1 . VAL B 2 152 ? -45.49955 -1.21481  46.53384  1.000 94.54384  ? 187 VAL F CG1 1 
ATOM   2694 C CG2 . VAL B 2 152 ? -44.51327 0.54123   45.00589  1.000 97.23909  ? 187 VAL F CG2 1 
ATOM   2695 N N   . LEU B 2 153 ? -42.21059 -0.00832  47.20454  1.000 103.92195 ? 188 LEU F N   1 
ATOM   2696 C CA  . LEU B 2 153 ? -41.74810 0.43918   48.51006  1.000 100.25063 ? 188 LEU F CA  1 
ATOM   2697 C C   . LEU B 2 153 ? -42.78366 1.35061   49.16691  1.000 91.12994  ? 188 LEU F C   1 
ATOM   2698 O O   . LEU B 2 153 ? -43.12580 2.40315   48.61741  1.000 95.54520  ? 188 LEU F O   1 
ATOM   2699 C CB  . LEU B 2 153 ? -40.40533 1.15755   48.36302  1.000 97.72997  ? 188 LEU F CB  1 
ATOM   2700 C CG  . LEU B 2 153 ? -39.60609 1.62671   49.58933  1.000 100.14779 ? 188 LEU F CG  1 
ATOM   2701 C CD1 . LEU B 2 153 ? -39.53396 0.51023   50.65986  1.000 105.78083 ? 188 LEU F CD1 1 
ATOM   2702 C CD2 . LEU B 2 153 ? -38.19408 2.07643   49.20287  1.000 100.10599 ? 188 LEU F CD2 1 
ATOM   2703 N N   . THR B 2 154 ? -43.26233 0.95640   50.34950  1.000 87.08441  ? 189 THR F N   1 
ATOM   2704 C CA  . THR B 2 154 ? -44.32090 1.66268   51.06059  1.000 88.28918  ? 189 THR F CA  1 
ATOM   2705 C C   . THR B 2 154 ? -43.71037 2.40027   52.24701  1.000 102.45814 ? 189 THR F C   1 
ATOM   2706 O O   . THR B 2 154 ? -42.80483 1.88617   52.91633  1.000 110.03246 ? 189 THR F O   1 
ATOM   2707 C CB  . THR B 2 154 ? -45.41857 0.70153   51.51740  1.000 92.34611  ? 189 THR F CB  1 
ATOM   2708 O OG1 . THR B 2 154 ? -44.87318 -0.25338  52.43242  1.000 118.96643 ? 189 THR F OG1 1 
ATOM   2709 C CG2 . THR B 2 154 ? -46.00993 -0.02066  50.32254  1.000 80.13146  ? 189 THR F CG2 1 
ATOM   2710 N N   . SER B 2 155 ? -44.19011 3.61242   52.49654  1.000 96.34369  ? 190 SER F N   1 
ATOM   2711 C CA  . SER B 2 155 ? -43.58625 4.45939   53.52051  1.000 96.25612  ? 190 SER F CA  1 
ATOM   2712 C C   . SER B 2 155 ? -44.67715 5.19336   54.28989  1.000 90.88139  ? 190 SER F C   1 
ATOM   2713 O O   . SER B 2 155 ? -45.52294 5.86772   53.68463  1.000 85.24285  ? 190 SER F O   1 
ATOM   2714 C CB  . SER B 2 155 ? -42.59905 5.46255   52.90200  1.000 92.30019  ? 190 SER F CB  1 
ATOM   2715 O OG  . SER B 2 155 ? -41.34030 4.86075   52.65698  1.000 88.09523  ? 190 SER F OG  1 
ATOM   2716 N N   . LYS B 2 156 ? -44.65754 5.03592   55.61846  1.000 94.33219  ? 191 LYS F N   1 
ATOM   2717 C CA  . LYS B 2 156 ? -45.58426 5.72814   56.51390  1.000 92.78904  ? 191 LYS F CA  1 
ATOM   2718 C C   . LYS B 2 156 ? -44.93328 7.01893   57.00324  1.000 89.91839  ? 191 LYS F C   1 
ATOM   2719 O O   . LYS B 2 156 ? -44.15761 7.00655   57.96528  1.000 98.72635  ? 191 LYS F O   1 
ATOM   2720 C CB  . LYS B 2 156 ? -45.97093 4.83355   57.68814  1.000 95.71047  ? 191 LYS F CB  1 
ATOM   2721 C CG  . LYS B 2 156 ? -47.08286 5.44462   58.52638  1.000 85.74647  ? 191 LYS F CG  1 
ATOM   2722 C CD  . LYS B 2 156 ? -47.76473 4.41869   59.39933  1.000 92.08774  ? 191 LYS F CD  1 
ATOM   2723 C CE  . LYS B 2 156 ? -46.76133 3.49190   60.07583  1.000 104.96922 ? 191 LYS F CE  1 
ATOM   2724 N NZ  . LYS B 2 156 ? -47.42254 2.41548   60.86544  1.000 108.06126 ? 191 LYS F NZ  1 
ATOM   2725 N N   . VAL B 2 157 ? -45.24419 8.13078   56.34131  1.000 83.95480  ? 192 VAL F N   1 
ATOM   2726 C CA  . VAL B 2 157 ? -44.56565 9.38315   56.61885  1.000 86.02278  ? 192 VAL F CA  1 
ATOM   2727 C C   . VAL B 2 157 ? -45.20850 10.19888  57.73360  1.000 85.54515  ? 192 VAL F C   1 
ATOM   2728 O O   . VAL B 2 157 ? -44.56990 11.12641  58.26296  1.000 90.34281  ? 192 VAL F O   1 
ATOM   2729 C CB  . VAL B 2 157 ? -44.46849 10.24775  55.35008  1.000 90.66493  ? 192 VAL F CB  1 
ATOM   2730 C CG1 . VAL B 2 157 ? -43.70744 9.49890   54.28489  1.000 90.90352  ? 192 VAL F CG1 1 
ATOM   2731 C CG2 . VAL B 2 157 ? -45.86409 10.60596  54.86763  1.000 84.87106  ? 192 VAL F CG2 1 
ATOM   2732 N N   . LEU B 2 158 ? -46.44520 9.89198   58.10750  1.000 81.06211  ? 193 LEU F N   1 
ATOM   2733 C CA  . LEU B 2 158 ? -47.13827 10.63835  59.14674  1.000 82.54765  ? 193 LEU F CA  1 
ATOM   2734 C C   . LEU B 2 158 ? -48.08821 9.71111   59.88993  1.000 84.12007  ? 193 LEU F C   1 
ATOM   2735 O O   . LEU B 2 158 ? -48.77873 8.90213   59.27436  1.000 78.73091  ? 193 LEU F O   1 
ATOM   2736 C CB  . LEU B 2 158 ? -47.91926 11.83084  58.57780  1.000 77.46209  ? 193 LEU F CB  1 
ATOM   2737 C CG  . LEU B 2 158 ? -48.46579 12.80588  59.61962  1.000 75.76104  ? 193 LEU F CG  1 
ATOM   2738 C CD1 . LEU B 2 158 ? -47.29884 13.41249  60.42756  1.000 79.46655  ? 193 LEU F CD1 1 
ATOM   2739 C CD2 . LEU B 2 158 ? -49.27775 13.89679  58.97538  1.000 76.49567  ? 193 LEU F CD2 1 
ATOM   2740 N N   . ASP B 2 159 ? -48.12659 9.84996   61.21456  1.000 86.52829  ? 194 ASP F N   1 
ATOM   2741 C CA  . ASP B 2 159 ? -48.95902 8.99704   62.05741  1.000 83.24115  ? 194 ASP F CA  1 
ATOM   2742 C C   . ASP B 2 159 ? -49.86720 9.89422   62.89024  1.000 75.54923  ? 194 ASP F C   1 
ATOM   2743 O O   . ASP B 2 159 ? -49.51270 10.30628  63.99761  1.000 74.51957  ? 194 ASP F O   1 
ATOM   2744 C CB  . ASP B 2 159 ? -48.08638 8.09645   62.93487  1.000 80.86569  ? 194 ASP F CB  1 
ATOM   2745 C CG  . ASP B 2 159 ? -48.85293 6.92766   63.52676  1.000 86.86273  ? 194 ASP F CG  1 
ATOM   2746 O OD1 . ASP B 2 159 ? -50.09311 7.00290   63.61677  1.000 85.57948  ? 194 ASP F OD1 1 
ATOM   2747 O OD2 . ASP B 2 159 ? -48.20930 5.92607   63.90543  1.000 93.65950  ? 194 ASP F OD2 1 
ATOM   2748 N N   . LEU B 2 160 ? -51.03980 10.20191  62.34287  1.000 74.35755  ? 195 LEU F N   1 
ATOM   2749 C CA  . LEU B 2 160 ? -52.03894 10.99454  63.04460  1.000 71.85267  ? 195 LEU F CA  1 
ATOM   2750 C C   . LEU B 2 160 ? -52.96531 10.14440  63.89792  1.000 76.20738  ? 195 LEU F C   1 
ATOM   2751 O O   . LEU B 2 160 ? -53.51797 10.64718  64.88133  1.000 73.32103  ? 195 LEU F O   1 
ATOM   2752 C CB  . LEU B 2 160 ? -52.88320 11.81000  62.05722  1.000 67.98378  ? 195 LEU F CB  1 
ATOM   2753 C CG  . LEU B 2 160 ? -52.21475 12.98706  61.35461  1.000 67.77955  ? 195 LEU F CG  1 
ATOM   2754 C CD1 . LEU B 2 160 ? -53.21451 13.68720  60.45912  1.000 63.32198  ? 195 LEU F CD1 1 
ATOM   2755 C CD2 . LEU B 2 160 ? -51.66309 13.95178  62.37903  1.000 69.10524  ? 195 LEU F CD2 1 
ATOM   2756 N N   . LYS B 2 161 ? -53.15010 8.87063   63.53839  1.000 78.50965  ? 196 LYS F N   1 
ATOM   2757 C CA  . LYS B 2 161 ? -53.99460 7.98872   64.33857  1.000 79.76213  ? 196 LYS F CA  1 
ATOM   2758 C C   . LYS B 2 161 ? -53.41433 7.77421   65.73392  1.000 88.11378  ? 196 LYS F C   1 
ATOM   2759 O O   . LYS B 2 161 ? -54.15675 7.75608   66.72356  1.000 93.64535  ? 196 LYS F O   1 
ATOM   2760 C CB  . LYS B 2 161 ? -54.20625 6.65990   63.60677  1.000 78.58225  ? 196 LYS F CB  1 
ATOM   2761 C CG  . LYS B 2 161 ? -55.12563 5.69491   64.33618  1.000 85.67244  ? 196 LYS F CG  1 
ATOM   2762 C CD  . LYS B 2 161 ? -55.44019 4.45246   63.50798  1.000 86.20929  ? 196 LYS F CD  1 
ATOM   2763 C CE  . LYS B 2 161 ? -54.23369 3.55192   63.32374  1.000 84.46003  ? 196 LYS F CE  1 
ATOM   2764 N NZ  . LYS B 2 161 ? -54.59395 2.33364   62.54485  1.000 76.44342  ? 196 LYS F NZ  1 
ATOM   2765 N N   . ASN B 2 162 ? -52.08724 7.67038   65.84270  1.000 88.17995  ? 197 ASN F N   1 
ATOM   2766 C CA  . ASN B 2 162 ? -51.46681 7.48324   67.15199  1.000 90.21890  ? 197 ASN F CA  1 
ATOM   2767 C C   . ASN B 2 162 ? -51.70157 8.69979   68.04431  1.000 87.74893  ? 197 ASN F C   1 
ATOM   2768 O O   . ASN B 2 162 ? -52.09738 8.55989   69.21239  1.000 82.81976  ? 197 ASN F O   1 
ATOM   2769 C CB  . ASN B 2 162 ? -49.97356 7.21798   66.96444  1.000 87.49335  ? 197 ASN F CB  1 
ATOM   2770 C CG  . ASN B 2 162 ? -49.23244 7.07296   68.27112  1.000 103.78165 ? 197 ASN F CG  1 
ATOM   2771 O OD1 . ASN B 2 162 ? -49.15125 5.98179   68.83430  1.000 117.26826 ? 197 ASN F OD1 1 
ATOM   2772 N ND2 . ASN B 2 162 ? -48.67293 8.17582   68.75820  1.000 104.68624 ? 197 ASN F ND2 1 
ATOM   2773 N N   . TYR B 2 163 ? -51.64305 9.89736   67.45712  1.000 85.29048  ? 198 TYR F N   1 
ATOM   2774 C CA  . TYR B 2 163 ? -51.80285 11.12089  68.23239  1.000 73.27523  ? 198 TYR F CA  1 
ATOM   2775 C C   . TYR B 2 163 ? -53.26514 11.33980  68.58299  1.000 74.76581  ? 198 TYR F C   1 
ATOM   2776 O O   . TYR B 2 163 ? -53.57632 11.75186  69.70435  1.000 79.78875  ? 198 TYR F O   1 
ATOM   2777 C CB  . TYR B 2 163 ? -51.25110 12.33149  67.47741  1.000 74.71066  ? 198 TYR F CB  1 
ATOM   2778 C CG  . TYR B 2 163 ? -51.15719 13.56980  68.34604  1.000 71.09968  ? 198 TYR F CG  1 
ATOM   2779 C CD1 . TYR B 2 163 ? -50.37793 13.58395  69.49482  1.000 79.94900  ? 198 TYR F CD1 1 
ATOM   2780 C CD2 . TYR B 2 163 ? -51.89742 14.70723  68.04459  1.000 67.65032  ? 198 TYR F CD2 1 
ATOM   2781 C CE1 . TYR B 2 163 ? -50.30996 14.71051  70.30011  1.000 89.00238  ? 198 TYR F CE1 1 
ATOM   2782 C CE2 . TYR B 2 163 ? -51.83886 15.83844  68.84497  1.000 68.00210  ? 198 TYR F CE2 1 
ATOM   2783 C CZ  . TYR B 2 163 ? -51.04480 15.83477  69.97251  1.000 77.48174  ? 198 TYR F CZ  1 
ATOM   2784 O OH  . TYR B 2 163 ? -50.97802 16.95526  70.77470  1.000 73.69735  ? 198 TYR F OH  1 
ATOM   2785 N N   . ILE B 2 164 ? -54.17925 11.04728  67.65660  1.000 72.94201  ? 199 ILE F N   1 
ATOM   2786 C CA  . ILE B 2 164 ? -55.59023 11.28876  67.93237  1.000 75.83500  ? 199 ILE F CA  1 
ATOM   2787 C C   . ILE B 2 164 ? -56.07791 10.29699  68.97809  1.000 81.10779  ? 199 ILE F C   1 
ATOM   2788 O O   . ILE B 2 164 ? -56.81257 10.66210  69.90535  1.000 79.27824  ? 199 ILE F O   1 
ATOM   2789 C CB  . ILE B 2 164 ? -56.42140 11.21609  66.63944  1.000 64.30991  ? 199 ILE F CB  1 
ATOM   2790 C CG1 . ILE B 2 164 ? -56.03325 12.36468  65.70817  1.000 65.29583  ? 199 ILE F CG1 1 
ATOM   2791 C CG2 . ILE B 2 164 ? -57.90983 11.25846  66.95618  1.000 63.56818  ? 199 ILE F CG2 1 
ATOM   2792 C CD1 . ILE B 2 164 ? -56.77959 12.38025  64.40177  1.000 75.57719  ? 199 ILE F CD1 1 
ATOM   2793 N N   . ASP B 2 165 ? -55.68648 9.02673   68.84910  1.000 84.44456  ? 200 ASP F N   1 
ATOM   2794 C CA  . ASP B 2 165 ? -56.18850 8.01946   69.76832  1.000 87.42223  ? 200 ASP F CA  1 
ATOM   2795 C C   . ASP B 2 165 ? -55.52908 8.14015   71.13905  1.000 84.07586  ? 200 ASP F C   1 
ATOM   2796 O O   . ASP B 2 165 ? -56.12082 7.72432   72.14090  1.000 83.16770  ? 200 ASP F O   1 
ATOM   2797 C CB  . ASP B 2 165 ? -55.95071 6.62023   69.19288  1.000 88.60659  ? 200 ASP F CB  1 
ATOM   2798 C CG  . ASP B 2 165 ? -56.76453 6.35025   67.93631  1.000 86.07181  ? 200 ASP F CG  1 
ATOM   2799 O OD1 . ASP B 2 165 ? -57.18953 7.31723   67.26908  1.000 84.22263  ? 200 ASP F OD1 1 
ATOM   2800 O OD2 . ASP B 2 165 ? -56.96805 5.15951   67.61501  1.000 87.60727  ? 200 ASP F OD2 1 
ATOM   2801 N N   . LYS B 2 166 ? -54.31769 8.69966   71.22284  1.000 75.20474  ? 201 LYS F N   1 
ATOM   2802 C CA  . LYS B 2 166 ? -53.68204 8.78143   72.53075  1.000 76.01107  ? 201 LYS F CA  1 
ATOM   2803 C C   . LYS B 2 166 ? -53.87701 10.11638  73.24852  1.000 77.53108  ? 201 LYS F C   1 
ATOM   2804 O O   . LYS B 2 166 ? -54.09756 10.12713  74.46187  1.000 85.61442  ? 201 LYS F O   1 
ATOM   2805 C CB  . LYS B 2 166 ? -52.18498 8.49712   72.38782  1.000 82.15813  ? 201 LYS F CB  1 
ATOM   2806 C CG  . LYS B 2 166 ? -51.86230 7.03014   72.12326  1.000 88.03515  ? 201 LYS F CG  1 
ATOM   2807 C CD  . LYS B 2 166 ? -52.08180 6.13492   73.33406  1.000 90.37083  ? 201 LYS F CD  1 
ATOM   2808 C CE  . LYS B 2 166 ? -51.12890 6.45683   74.47339  1.000 82.58210  ? 201 LYS F CE  1 
ATOM   2809 N NZ  . LYS B 2 166 ? -51.35419 5.56824   75.65047  1.000 63.39937  ? 201 LYS F NZ  1 
ATOM   2810 N N   . GLN B 2 167 ? -53.81415 11.24627  72.53762  1.000 74.17735  ? 202 GLN F N   1 
ATOM   2811 C CA  . GLN B 2 167 ? -53.83812 12.56473  73.16439  1.000 70.51142  ? 202 GLN F CA  1 
ATOM   2812 C C   . GLN B 2 167 ? -55.12622 13.37363  73.04336  1.000 62.21827  ? 202 GLN F C   1 
ATOM   2813 O O   . GLN B 2 167 ? -55.34588 14.25868  73.87558  1.000 68.16942  ? 202 GLN F O   1 
ATOM   2814 C CB  . GLN B 2 167 ? -52.69877 13.43646  72.60965  1.000 79.44975  ? 202 GLN F CB  1 
ATOM   2815 C CG  . GLN B 2 167 ? -51.47089 13.54601  73.49584  1.000 67.66842  ? 202 GLN F CG  1 
ATOM   2816 C CD  . GLN B 2 167 ? -50.73252 12.23266  73.65428  1.000 72.91773  ? 202 GLN F CD  1 
ATOM   2817 O OE1 . GLN B 2 167 ? -50.73253 11.38797  72.75360  1.000 74.06992  ? 202 GLN F OE1 1 
ATOM   2818 N NE2 . GLN B 2 167 ? -50.07465 12.06425  74.78824  1.000 82.73853  ? 202 GLN F NE2 1 
ATOM   2819 N N   . LEU B 2 168 ? -55.97410 13.12370  72.05213  1.000 53.99754  ? 203 LEU F N   1 
ATOM   2820 C CA  . LEU B 2 168 ? -57.13981 13.98630  71.84058  1.000 62.93160  ? 203 LEU F CA  1 
ATOM   2821 C C   . LEU B 2 168 ? -58.49163 13.39036  72.20102  1.000 72.14935  ? 203 LEU F C   1 
ATOM   2822 O O   . LEU B 2 168 ? -59.31249 14.08315  72.81457  1.000 80.99013  ? 203 LEU F O   1 
ATOM   2823 C CB  . LEU B 2 168 ? -57.18548 14.43710  70.37121  1.000 57.97112  ? 203 LEU F CB  1 
ATOM   2824 C CG  . LEU B 2 168 ? -55.97385 15.26543  69.91761  1.000 64.35432  ? 203 LEU F CG  1 
ATOM   2825 C CD1 . LEU B 2 168 ? -55.72384 15.00650  68.45723  1.000 71.47259  ? 203 LEU F CD1 1 
ATOM   2826 C CD2 . LEU B 2 168 ? -56.21526 16.74765  70.17265  1.000 63.76408  ? 203 LEU F CD2 1 
ATOM   2827 N N   . LEU B 2 169 ? -58.76646 12.13833  71.84284  1.000 64.91449  ? 204 LEU F N   1 
ATOM   2828 C CA  . LEU B 2 169 ? -60.08554 11.58199  72.13533  1.000 67.51560  ? 204 LEU F CA  1 
ATOM   2829 C C   . LEU B 2 169 ? -60.42440 11.49366  73.61940  1.000 76.52560  ? 204 LEU F C   1 
ATOM   2830 O O   . LEU B 2 169 ? -61.57087 11.83522  73.97213  1.000 83.05105  ? 204 LEU F O   1 
ATOM   2831 C CB  . LEU B 2 169 ? -60.22933 10.21349  71.46635  1.000 66.46911  ? 204 LEU F CB  1 
ATOM   2832 C CG  . LEU B 2 169 ? -60.65456 10.30272  70.00111  1.000 64.80645  ? 204 LEU F CG  1 
ATOM   2833 C CD1 . LEU B 2 169 ? -60.91516 8.91647   69.47133  1.000 71.01272  ? 204 LEU F CD1 1 
ATOM   2834 C CD2 . LEU B 2 169 ? -61.88877 11.18593  69.84296  1.000 74.87111  ? 204 LEU F CD2 1 
ATOM   2835 N N   . PRO B 2 170 ? -59.52927 11.07112  74.52283  1.000 71.62097  ? 205 PRO F N   1 
ATOM   2836 C CA  . PRO B 2 170 ? -59.88229 11.11373  75.95032  1.000 73.41757  ? 205 PRO F CA  1 
ATOM   2837 C C   . PRO B 2 170 ? -60.17646 12.50322  76.49053  1.000 81.67670  ? 205 PRO F C   1 
ATOM   2838 O O   . PRO B 2 170 ? -60.77188 12.61375  77.57005  1.000 92.35476  ? 205 PRO F O   1 
ATOM   2839 C CB  . PRO B 2 170 ? -58.64749 10.51285  76.63646  1.000 66.42660  ? 205 PRO F CB  1 
ATOM   2840 C CG  . PRO B 2 170 ? -57.99383 9.69582   75.58679  1.000 68.80906  ? 205 PRO F CG  1 
ATOM   2841 C CD  . PRO B 2 170 ? -58.21634 10.43680  74.30850  1.000 67.47683  ? 205 PRO F CD  1 
ATOM   2842 N N   . ILE B 2 171 ? -59.77441 13.56671  75.80614  1.000 75.34983  ? 206 ILE F N   1 
ATOM   2843 C CA  . ILE B 2 171 ? -60.07387 14.90749  76.29664  1.000 74.85976  ? 206 ILE F CA  1 
ATOM   2844 C C   . ILE B 2 171 ? -61.42047 15.44746  75.79447  1.000 68.93868  ? 206 ILE F C   1 
ATOM   2845 O O   . ILE B 2 171 ? -62.08442 16.20298  76.51588  1.000 75.50769  ? 206 ILE F O   1 
ATOM   2846 C CB  . ILE B 2 171 ? -58.91915 15.86707  75.95956  1.000 76.12672  ? 206 ILE F CB  1 
ATOM   2847 C CG1 . ILE B 2 171 ? -57.62031 15.37676  76.62683  1.000 80.82808  ? 206 ILE F CG1 1 
ATOM   2848 C CG2 . ILE B 2 171 ? -59.22251 17.26096  76.44197  1.000 92.15182  ? 206 ILE F CG2 1 
ATOM   2849 C CD1 . ILE B 2 171 ? -57.71022 15.31119  78.15951  1.000 87.63726  ? 206 ILE F CD1 1 
ATOM   2850 N N   . VAL B 2 172 ? -61.87950 15.04534  74.60674  1.000 68.25315  ? 207 VAL F N   1 
ATOM   2851 C CA  . VAL B 2 172 ? -63.07011 15.65680  74.02723  1.000 85.79851  ? 207 VAL F CA  1 
ATOM   2852 C C   . VAL B 2 172 ? -64.18450 14.64270  73.77817  1.000 93.00225  ? 207 VAL F C   1 
ATOM   2853 O O   . VAL B 2 172 ? -65.10491 14.91016  73.00777  1.000 98.62193  ? 207 VAL F O   1 
ATOM   2854 C CB  . VAL B 2 172 ? -62.72342 16.43240  72.74177  1.000 84.85245  ? 207 VAL F CB  1 
ATOM   2855 C CG1 . VAL B 2 172 ? -61.96148 17.70518  73.07530  1.000 87.42254  ? 207 VAL F CG1 1 
ATOM   2856 C CG2 . VAL B 2 172 ? -61.93616 15.55321  71.77408  1.000 76.49244  ? 207 VAL F CG2 1 
ATOM   2857 N N   . ASN B 2 173 ? -64.12779 13.48294  74.42475  1.000 85.60990  ? 208 ASN F N   1 
ATOM   2858 C CA  . ASN B 2 173 ? -65.18299 12.48343  74.28083  1.000 91.75815  ? 208 ASN F CA  1 
ATOM   2859 C C   . ASN B 2 173 ? -65.85330 12.18924  75.61814  1.000 92.22449  ? 208 ASN F C   1 
ATOM   2860 O O   . ASN B 2 173 ? -66.43655 11.12783  75.81248  1.000 87.72920  ? 208 ASN F O   1 
ATOM   2861 C CB  . ASN B 2 173 ? -64.65451 11.18606  73.66498  1.000 88.06509  ? 208 ASN F CB  1 
ATOM   2862 C CG  . ASN B 2 173 ? -65.13135 10.97551  72.24160  1.000 99.70966  ? 208 ASN F CG  1 
ATOM   2863 O OD1 . ASN B 2 173 ? -65.45830 11.93785  71.54719  1.000 105.01466 ? 208 ASN F OD1 1 
ATOM   2864 N ND2 . ASN B 2 173 ? -65.22852 9.71666   71.81912  1.000 95.56967  ? 208 ASN F ND2 1 
ATOM   2865 N N   . LYS B 2 174 ? -65.82048 13.14880  76.53358  1.000 95.48506  ? 209 LYS F N   1 
ATOM   2866 C CA  . LYS B 2 174 ? -66.44757 13.00161  77.83662  1.000 108.44179 ? 209 LYS F CA  1 
ATOM   2867 C C   . LYS B 2 174 ? -67.88460 13.51312  77.75871  1.000 124.72130 ? 209 LYS F C   1 
ATOM   2868 O O   . LYS B 2 174 ? -68.36863 13.86643  76.67745  1.000 122.49189 ? 209 LYS F O   1 
ATOM   2869 C CB  . LYS B 2 174 ? -65.63567 13.76025  78.88484  1.000 88.23791  ? 209 LYS F CB  1 
ATOM   2870 C CG  . LYS B 2 174 ? -64.21109 13.25882  79.07262  1.000 77.20870  ? 209 LYS F CG  1 
ATOM   2871 C CD  . LYS B 2 174 ? -63.75157 13.39653  80.50219  1.000 74.69767  ? 209 LYS F CD  1 
ATOM   2872 C CE  . LYS B 2 174 ? -62.27122 13.71086  80.56347  1.000 74.46379  ? 209 LYS F CE  1 
ATOM   2873 N NZ  . LYS B 2 174 ? -61.83600 14.26279  81.87650  1.000 72.76589  ? 209 LYS F NZ  1 
ATOM   2874 N N   . GLN B 2 175 ? -68.58337 13.54935  78.90241  1.000 131.29298 ? 210 GLN F N   1 
ATOM   2875 C CA  . GLN B 2 175 ? -69.92844 14.10865  78.90986  1.000 138.59861 ? 210 GLN F CA  1 
ATOM   2876 C C   . GLN B 2 175 ? -69.83490 15.60697  78.69744  1.000 138.12124 ? 210 GLN F C   1 
ATOM   2877 O O   . GLN B 2 175 ? -70.51012 16.17301  77.82934  1.000 138.30200 ? 210 GLN F O   1 
ATOM   2878 C CB  . GLN B 2 175 ? -70.66491 13.76418  80.19868  1.000 148.23704 ? 210 GLN F CB  1 
ATOM   2879 C CG  . GLN B 2 175 ? -71.54201 12.53390  80.02849  1.000 145.63015 ? 210 GLN F CG  1 
ATOM   2880 C CD  . GLN B 2 175 ? -72.89337 12.68088  80.68676  1.000 148.80594 ? 210 GLN F CD  1 
ATOM   2881 O OE1 . GLN B 2 175 ? -73.19212 13.71244  81.28596  1.000 153.86102 ? 210 GLN F OE1 1 
ATOM   2882 N NE2 . GLN B 2 175 ? -73.72523 11.65782  80.56380  1.000 140.97497 ? 210 GLN F NE2 1 
ATOM   2883 N N   . SER B 2 176 ? -69.01539 16.26735  79.50236  1.000 135.55085 ? 211 SER F N   1 
ATOM   2884 C CA  . SER B 2 176 ? -68.69294 17.66365  79.30437  1.000 135.39716 ? 211 SER F CA  1 
ATOM   2885 C C   . SER B 2 176 ? -67.21248 17.65240  78.97718  1.000 123.20745 ? 211 SER F C   1 
ATOM   2886 O O   . SER B 2 176 ? -66.45053 16.86470  79.55073  1.000 103.39411 ? 211 SER F O   1 
ATOM   2887 C CB  . SER B 2 176 ? -68.94941 18.50324  80.55649  1.000 136.65941 ? 211 SER F CB  1 
ATOM   2888 O OG  . SER B 2 176 ? -70.31436 18.48844  80.93631  1.000 144.20801 ? 211 SER F OG  1 
ATOM   2889 N N   . CYS B 2 177 ? -66.80184 18.51485  78.05930  1.000 120.43816 ? 212 CYS F N   1 
ATOM   2890 C CA  . CYS B 2 177 ? -65.41266 18.47917  77.64188  1.000 104.10203 ? 212 CYS F CA  1 
ATOM   2891 C C   . CYS B 2 177 ? -64.49827 18.87415  78.78337  1.000 102.40511 ? 212 CYS F C   1 
ATOM   2892 O O   . CYS B 2 177 ? -64.75273 19.83677  79.51516  1.000 101.43637 ? 212 CYS F O   1 
ATOM   2893 C CB  . CYS B 2 177 ? -65.17334 19.35263  76.41590  1.000 94.36510  ? 212 CYS F CB  1 
ATOM   2894 S SG  . CYS B 2 177 ? -65.55025 18.49611  74.85205  1.000 112.76064 ? 212 CYS F SG  1 
ATOM   2895 N N   . SER B 2 178 ? -63.42258 18.11918  78.92504  1.000 98.51179  ? 213 SER F N   1 
ATOM   2896 C CA  . SER B 2 178 ? -62.40820 18.57030  79.83871  1.000 92.91484  ? 213 SER F CA  1 
ATOM   2897 C C   . SER B 2 178 ? -61.64049 19.69390  79.17137  1.000 80.26246  ? 213 SER F C   1 
ATOM   2898 O O   . SER B 2 178 ? -61.62412 19.83204  77.94462  1.000 66.51295  ? 213 SER F O   1 
ATOM   2899 C CB  . SER B 2 178 ? -61.47296 17.42341  80.22242  1.000 86.35748  ? 213 SER F CB  1 
ATOM   2900 O OG  . SER B 2 178 ? -60.53071 17.83795  81.19211  1.000 96.20890  ? 213 SER F OG  1 
ATOM   2901 N N   . ILE B 2 179 ? -61.00732 20.51383  79.99964  1.000 91.47009  ? 214 ILE F N   1 
ATOM   2902 C CA  . ILE B 2 179 ? -60.31238 21.70616  79.53358  1.000 89.45271  ? 214 ILE F CA  1 
ATOM   2903 C C   . ILE B 2 179 ? -58.89435 21.27650  79.17034  1.000 84.06966  ? 214 ILE F C   1 
ATOM   2904 O O   . ILE B 2 179 ? -58.10978 20.94602  80.07592  1.000 87.79480  ? 214 ILE F O   1 
ATOM   2905 C CB  . ILE B 2 179 ? -60.32297 22.80533  80.59935  1.000 98.95756  ? 214 ILE F CB  1 
ATOM   2906 C CG1 . ILE B 2 179 ? -61.76930 23.12071  80.99480  1.000 104.02617 ? 214 ILE F CG1 1 
ATOM   2907 C CG2 . ILE B 2 179 ? -59.64936 24.04561  80.07849  1.000 88.67336  ? 214 ILE F CG2 1 
ATOM   2908 C CD1 . ILE B 2 179 ? -62.66122 23.48105  79.82753  1.000 82.47888  ? 214 ILE F CD1 1 
ATOM   2909 N N   . PRO B 2 180 ? -58.52425 21.29040  77.89842  1.000 78.74785  ? 215 PRO F N   1 
ATOM   2910 C CA  . PRO B 2 180 ? -57.15316 20.98247  77.49644  1.000 80.19026  ? 215 PRO F CA  1 
ATOM   2911 C C   . PRO B 2 180 ? -56.20399 22.16766  77.53880  1.000 89.34344  ? 215 PRO F C   1 
ATOM   2912 O O   . PRO B 2 180 ? -56.57834 23.32277  77.33630  1.000 96.03827  ? 215 PRO F O   1 
ATOM   2913 C CB  . PRO B 2 180 ? -57.33986 20.49441  76.05265  1.000 83.18233  ? 215 PRO F CB  1 
ATOM   2914 C CG  . PRO B 2 180 ? -58.49981 21.30373  75.55191  1.000 74.76735  ? 215 PRO F CG  1 
ATOM   2915 C CD  . PRO B 2 180 ? -59.40371 21.53195  76.73967  1.000 81.75648  ? 215 PRO F CD  1 
ATOM   2916 N N   . ASN B 2 181 ? -54.94192 21.86059  77.80856  1.000 85.33144  ? 216 ASN F N   1 
ATOM   2917 C CA  . ASN B 2 181 ? -53.94562 22.91507  77.82918  1.000 80.82480  ? 216 ASN F CA  1 
ATOM   2918 C C   . ASN B 2 181 ? -53.60567 23.31032  76.39057  1.000 86.10830  ? 216 ASN F C   1 
ATOM   2919 O O   . ASN B 2 181 ? -53.79822 22.54622  75.44062  1.000 91.64717  ? 216 ASN F O   1 
ATOM   2920 C CB  . ASN B 2 181 ? -52.71920 22.46840  78.61974  1.000 73.85174  ? 216 ASN F CB  1 
ATOM   2921 C CG  . ASN B 2 181 ? -52.26402 21.08960  78.23476  1.000 85.70799  ? 216 ASN F CG  1 
ATOM   2922 O OD1 . ASN B 2 181 ? -52.58034 20.10974  78.90983  1.000 89.29557  ? 216 ASN F OD1 1 
ATOM   2923 N ND2 . ASN B 2 181 ? -51.51241 20.99825  77.14778  1.000 92.83887  ? 216 ASN F ND2 1 
ATOM   2924 N N   . ILE B 2 182 ? -53.09505 24.53135  76.24205  1.000 73.78664  ? 217 ILE F N   1 
ATOM   2925 C CA  . ILE B 2 182 ? -52.75961 25.08318  74.93280  1.000 68.88088  ? 217 ILE F CA  1 
ATOM   2926 C C   . ILE B 2 182 ? -51.62651 24.35884  74.19376  1.000 65.73068  ? 217 ILE F C   1 
ATOM   2927 O O   . ILE B 2 182 ? -51.58568 24.39895  72.95330  1.000 65.94941  ? 217 ILE F O   1 
ATOM   2928 C CB  . ILE B 2 182 ? -52.45365 26.57964  75.11663  1.000 73.46605  ? 217 ILE F CB  1 
ATOM   2929 C CG1 . ILE B 2 182 ? -52.60220 27.31983  73.78723  1.000 64.16153  ? 217 ILE F CG1 1 
ATOM   2930 C CG2 . ILE B 2 182 ? -51.07576 26.76975  75.73465  1.000 85.33103  ? 217 ILE F CG2 1 
ATOM   2931 C CD1 . ILE B 2 182 ? -54.00692 27.24956  73.20957  1.000 61.72443  ? 217 ILE F CD1 1 
ATOM   2932 N N   . GLU B 2 183 ? -50.75352 23.62839  74.89866  1.000 69.48338  ? 218 GLU F N   1 
ATOM   2933 C CA  . GLU B 2 183 ? -49.71591 22.85229  74.21406  1.000 70.14909  ? 218 GLU F CA  1 
ATOM   2934 C C   . GLU B 2 183 ? -50.30911 21.76099  73.33071  1.000 73.02790  ? 218 GLU F C   1 
ATOM   2935 O O   . GLU B 2 183 ? -49.79884 21.49433  72.23309  1.000 75.15982  ? 218 GLU F O   1 
ATOM   2936 C CB  . GLU B 2 183 ? -48.76131 22.22485  75.23651  1.000 73.54951  ? 218 GLU F CB  1 
ATOM   2937 C CG  . GLU B 2 183 ? -47.88884 23.21177  76.00706  1.000 87.22630  ? 218 GLU F CG  1 
ATOM   2938 C CD  . GLU B 2 183 ? -48.59439 23.80954  77.21471  1.000 103.12570 ? 218 GLU F CD  1 
ATOM   2939 O OE1 . GLU B 2 183 ? -49.76521 23.44901  77.46134  1.000 105.33344 ? 218 GLU F OE1 1 
ATOM   2940 O OE2 . GLU B 2 183 ? -47.98108 24.64834  77.91191  1.000 110.17873 ? 218 GLU F OE2 1 
ATOM   2941 N N   . THR B 2 184 ? -51.39308 21.13199  73.77607  1.000 70.41203  ? 219 THR F N   1 
ATOM   2942 C CA  . THR B 2 184 ? -52.02877 20.11768  72.94658  1.000 69.17437  ? 219 THR F CA  1 
ATOM   2943 C C   . THR B 2 184 ? -52.65337 20.74701  71.70873  1.000 68.90699  ? 219 THR F C   1 
ATOM   2944 O O   . THR B 2 184 ? -52.56893 20.18710  70.60849  1.000 74.12058  ? 219 THR F O   1 
ATOM   2945 C CB  . THR B 2 184 ? -53.07503 19.35899  73.75199  1.000 70.67750  ? 219 THR F CB  1 
ATOM   2946 O OG1 . THR B 2 184 ? -52.42880 18.67423  74.83208  1.000 79.26139  ? 219 THR F OG1 1 
ATOM   2947 C CG2 . THR B 2 184 ? -53.76624 18.34279  72.86360  1.000 75.05528  ? 219 THR F CG2 1 
ATOM   2948 N N   . VAL B 2 185 ? -53.27218 21.91790  71.87010  1.000 62.59705  ? 220 VAL F N   1 
ATOM   2949 C CA  . VAL B 2 185 ? -53.88573 22.60666  70.73925  1.000 59.52235  ? 220 VAL F CA  1 
ATOM   2950 C C   . VAL B 2 185 ? -52.84019 22.95281  69.68360  1.000 62.99682  ? 220 VAL F C   1 
ATOM   2951 O O   . VAL B 2 185 ? -53.05139 22.73039  68.48043  1.000 64.94439  ? 220 VAL F O   1 
ATOM   2952 C CB  . VAL B 2 185 ? -54.62952 23.86032  71.22962  1.000 57.82751  ? 220 VAL F CB  1 
ATOM   2953 C CG1 . VAL B 2 185 ? -55.20014 24.62516  70.05379  1.000 63.96719  ? 220 VAL F CG1 1 
ATOM   2954 C CG2 . VAL B 2 185 ? -55.71672 23.47235  72.20942  1.000 62.68496  ? 220 VAL F CG2 1 
ATOM   2955 N N   . ILE B 2 186 ? -51.66369 23.41896  70.11017  1.000 62.74660  ? 221 ILE F N   1 
ATOM   2956 C CA  . ILE B 2 186 ? -50.66256 23.77812  69.10809  1.000 61.16776  ? 221 ILE F CA  1 
ATOM   2957 C C   . ILE B 2 186 ? -50.04261 22.53415  68.48187  1.000 66.85975  ? 221 ILE F C   1 
ATOM   2958 O O   . ILE B 2 186 ? -49.84691 22.47956  67.25749  1.000 72.51155  ? 221 ILE F O   1 
ATOM   2959 C CB  . ILE B 2 186 ? -49.59055 24.70172  69.70909  1.000 56.13841  ? 221 ILE F CB  1 
ATOM   2960 C CG1 . ILE B 2 186 ? -50.19466 26.05493  70.05488  1.000 58.41437  ? 221 ILE F CG1 1 
ATOM   2961 C CG2 . ILE B 2 186 ? -48.42953 24.88373  68.75207  1.000 64.56515  ? 221 ILE F CG2 1 
ATOM   2962 C CD1 . ILE B 2 186 ? -49.19259 26.99738  70.64879  1.000 60.89620  ? 221 ILE F CD1 1 
ATOM   2963 N N   . GLU B 2 187 ? -49.74331 21.50670  69.28583  1.000 64.07224  ? 222 GLU F N   1 
ATOM   2964 C CA  . GLU B 2 187 ? -49.14863 20.31147  68.69609  1.000 65.76371  ? 222 GLU F CA  1 
ATOM   2965 C C   . GLU B 2 187 ? -50.11224 19.65260  67.71773  1.000 62.87842  ? 222 GLU F C   1 
ATOM   2966 O O   . GLU B 2 187 ? -49.68425 19.09726  66.69456  1.000 66.92225  ? 222 GLU F O   1 
ATOM   2967 C CB  . GLU B 2 187 ? -48.70940 19.32732  69.78033  1.000 70.83601  ? 222 GLU F CB  1 
ATOM   2968 C CG  . GLU B 2 187 ? -47.67771 18.32201  69.28006  1.000 81.35734  ? 222 GLU F CG  1 
ATOM   2969 C CD  . GLU B 2 187 ? -47.07108 17.49739  70.39177  1.000 100.99580 ? 222 GLU F CD  1 
ATOM   2970 O OE1 . GLU B 2 187 ? -47.65939 17.46260  71.49493  1.000 85.99774  ? 222 GLU F OE1 1 
ATOM   2971 O OE2 . GLU B 2 187 ? -46.00783 16.88213  70.15698  1.000 126.73720 ? 222 GLU F OE2 1 
ATOM   2972 N N   . PHE B 2 188 ? -51.41879 19.77143  67.96604  1.000 60.74594  ? 223 PHE F N   1 
ATOM   2973 C CA  . PHE B 2 188 ? -52.36992 19.18633  67.03638  1.000 61.84905  ? 223 PHE F CA  1 
ATOM   2974 C C   . PHE B 2 188 ? -52.52237 20.03050  65.78311  1.000 67.59108  ? 223 PHE F C   1 
ATOM   2975 O O   . PHE B 2 188 ? -52.72226 19.47108  64.69829  1.000 74.38342  ? 223 PHE F O   1 
ATOM   2976 C CB  . PHE B 2 188 ? -53.72672 18.99248  67.72157  1.000 66.07873  ? 223 PHE F CB  1 
ATOM   2977 C CG  . PHE B 2 188 ? -54.75569 18.32000  66.85310  1.000 68.01638  ? 223 PHE F CG  1 
ATOM   2978 C CD1 . PHE B 2 188 ? -54.45465 17.16372  66.15737  1.000 63.81452  ? 223 PHE F CD1 1 
ATOM   2979 C CD2 . PHE B 2 188 ? -56.03840 18.83712  66.75567  1.000 72.89697  ? 223 PHE F CD2 1 
ATOM   2980 C CE1 . PHE B 2 188 ? -55.40536 16.55211  65.35895  1.000 61.86402  ? 223 PHE F CE1 1 
ATOM   2981 C CE2 . PHE B 2 188 ? -56.99495 18.22352  65.96221  1.000 70.78905  ? 223 PHE F CE2 1 
ATOM   2982 C CZ  . PHE B 2 188 ? -56.67533 17.08058  65.26515  1.000 66.43209  ? 223 PHE F CZ  1 
ATOM   2983 N N   . GLN B 2 189 ? -52.39237 21.35884  65.88218  1.000 68.31109  ? 224 GLN F N   1 
ATOM   2984 C CA  . GLN B 2 189 ? -52.43321 22.13074  64.64352  1.000 72.56059  ? 224 GLN F CA  1 
ATOM   2985 C C   . GLN B 2 189 ? -51.20184 21.84897  63.78934  1.000 70.02812  ? 224 GLN F C   1 
ATOM   2986 O O   . GLN B 2 189 ? -51.31146 21.72896  62.55778  1.000 72.21756  ? 224 GLN F O   1 
ATOM   2987 C CB  . GLN B 2 189 ? -52.54521 23.62590  64.94664  1.000 75.35404  ? 224 GLN F CB  1 
ATOM   2988 C CG  . GLN B 2 189 ? -53.86349 24.02985  65.57636  1.000 70.77293  ? 224 GLN F CG  1 
ATOM   2989 C CD  . GLN B 2 189 ? -53.91003 25.49737  65.95592  1.000 66.57858  ? 224 GLN F CD  1 
ATOM   2990 O OE1 . GLN B 2 189 ? -52.91420 26.21585  65.85210  1.000 60.34428  ? 224 GLN F OE1 1 
ATOM   2991 N NE2 . GLN B 2 189 ? -55.07691 25.95231  66.39185  1.000 72.19416  ? 224 GLN F NE2 1 
ATOM   2992 N N   . GLN B 2 190 ? -50.07337 21.54735  64.44160  1.000 65.13793  ? 225 GLN F N   1 
ATOM   2993 C CA  . GLN B 2 190 ? -48.85443 21.21556  63.70712  1.000 65.62568  ? 225 GLN F CA  1 
ATOM   2994 C C   . GLN B 2 190 ? -48.96934 19.86541  63.02088  1.000 66.94630  ? 225 GLN F C   1 
ATOM   2995 O O   . GLN B 2 190 ? -48.56784 19.71696  61.86081  1.000 64.80276  ? 225 GLN F O   1 
ATOM   2996 C CB  . GLN B 2 190 ? -47.63973 21.22885  64.63400  1.000 64.94898  ? 225 GLN F CB  1 
ATOM   2997 C CG  . GLN B 2 190 ? -47.35802 22.55799  65.28456  1.000 74.73678  ? 225 GLN F CG  1 
ATOM   2998 C CD  . GLN B 2 190 ? -46.91991 23.59338  64.27004  1.000 83.66014  ? 225 GLN F CD  1 
ATOM   2999 O OE1 . GLN B 2 190 ? -47.63601 24.55370  63.99129  1.000 85.65833  ? 225 GLN F OE1 1 
ATOM   3000 N NE2 . GLN B 2 190 ? -45.73652 23.39056  63.69698  1.000 83.38613  ? 225 GLN F NE2 1 
ATOM   3001 N N   . LYS B 2 191 ? -49.50404 18.86443  63.71350  1.000 70.84800  ? 226 LYS F N   1 
ATOM   3002 C CA  . LYS B 2 191 ? -49.61325 17.56149  63.06899  1.000 63.39666  ? 226 LYS F CA  1 
ATOM   3003 C C   . LYS B 2 191 ? -50.67309 17.57736  61.96404  1.000 58.70727  ? 226 LYS F C   1 
ATOM   3004 O O   . LYS B 2 191 ? -50.45909 16.99991  60.89281  1.000 59.23175  ? 226 LYS F O   1 
ATOM   3005 C CB  . LYS B 2 191 ? -49.90361 16.48439  64.11726  1.000 69.54358  ? 226 LYS F CB  1 
ATOM   3006 C CG  . LYS B 2 191 ? -48.67089 16.06530  64.93880  1.000 78.39627  ? 226 LYS F CG  1 
ATOM   3007 C CD  . LYS B 2 191 ? -48.85023 14.72121  65.64487  1.000 80.26004  ? 226 LYS F CD  1 
ATOM   3008 C CE  . LYS B 2 191 ? -47.88006 13.66665  65.11024  1.000 82.20613  ? 226 LYS F CE  1 
ATOM   3009 N NZ  . LYS B 2 191 ? -48.21929 13.19582  63.73557  1.000 77.81108  ? 226 LYS F NZ  1 
ATOM   3010 N N   . ASN B 2 192 ? -51.82434 18.22361  62.19975  1.000 64.81058  ? 227 ASN F N   1 
ATOM   3011 C CA  . ASN B 2 192 ? -52.90856 18.24795  61.21379  1.000 68.00354  ? 227 ASN F CA  1 
ATOM   3012 C C   . ASN B 2 192 ? -52.60579 19.12537  59.99143  1.000 71.32298  ? 227 ASN F C   1 
ATOM   3013 O O   . ASN B 2 192 ? -53.27837 18.98282  58.95248  1.000 73.03498  ? 227 ASN F O   1 
ATOM   3014 C CB  . ASN B 2 192 ? -54.20230 18.71010  61.90012  1.000 75.32932  ? 227 ASN F CB  1 
ATOM   3015 C CG  . ASN B 2 192 ? -55.44368 18.49140  61.04323  1.000 78.82471  ? 227 ASN F CG  1 
ATOM   3016 O OD1 . ASN B 2 192 ? -55.51292 17.54773  60.25513  1.000 79.92697  ? 227 ASN F OD1 1 
ATOM   3017 N ND2 . ASN B 2 192 ? -56.43885 19.35694  61.21193  1.000 80.92464  ? 227 ASN F ND2 1 
ATOM   3018 N N   . ASN B 2 193 ? -51.61418 20.02238  60.07936  1.000 73.41917  ? 228 ASN F N   1 
ATOM   3019 C CA  . ASN B 2 193 ? -51.38603 20.95526  58.97664  1.000 75.98797  ? 228 ASN F CA  1 
ATOM   3020 C C   . ASN B 2 193 ? -50.98121 20.23579  57.68972  1.000 69.56570  ? 228 ASN F C   1 
ATOM   3021 O O   . ASN B 2 193 ? -51.47268 20.57415  56.60280  1.000 68.00892  ? 228 ASN F O   1 
ATOM   3022 C CB  . ASN B 2 193 ? -50.32201 21.97681  59.38042  1.000 83.15536  ? 228 ASN F CB  1 
ATOM   3023 C CG  . ASN B 2 193 ? -50.04865 23.00133  58.29448  1.000 89.45217  ? 228 ASN F CG  1 
ATOM   3024 O OD1 . ASN B 2 193 ? -50.97526 23.53901  57.68826  1.000 101.48210 ? 228 ASN F OD1 1 
ATOM   3025 N ND2 . ASN B 2 193 ? -48.77104 23.27413  58.04109  1.000 83.36484  ? 228 ASN F ND2 1 
ATOM   3026 N N   . ARG B 2 194 ? -50.07267 19.25817  57.78230  1.000 65.79320  ? 229 ARG F N   1 
ATOM   3027 C CA  . ARG B 2 194 ? -49.62834 18.57416  56.57149  1.000 56.40879  ? 229 ARG F CA  1 
ATOM   3028 C C   . ARG B 2 194 ? -50.77181 17.82741  55.90771  1.000 56.40004  ? 229 ARG F C   1 
ATOM   3029 O O   . ARG B 2 194 ? -50.86770 17.80723  54.67333  1.000 64.50494  ? 229 ARG F O   1 
ATOM   3030 C CB  . ARG B 2 194 ? -48.49697 17.59517  56.89210  1.000 57.30080  ? 229 ARG F CB  1 
ATOM   3031 C CG  . ARG B 2 194 ? -47.83872 16.98082  55.66484  1.000 63.09529  ? 229 ARG F CG  1 
ATOM   3032 C CD  . ARG B 2 194 ? -46.66956 16.08253  56.04148  1.000 70.19430  ? 229 ARG F CD  1 
ATOM   3033 N NE  . ARG B 2 194 ? -45.97253 15.57517  54.86560  1.000 77.22820  ? 229 ARG F NE  1 
ATOM   3034 C CZ  . ARG B 2 194 ? -44.91641 14.77386  54.90661  1.000 82.73646  ? 229 ARG F CZ  1 
ATOM   3035 N NH1 . ARG B 2 194 ? -44.40489 14.36283  56.05504  1.000 90.73292  ? 229 ARG F NH1 1 
ATOM   3036 N NH2 . ARG B 2 194 ? -44.36169 14.37125  53.76622  1.000 79.14426  ? 229 ARG F NH2 1 
ATOM   3037 N N   . LEU B 2 195 ? -51.69253 17.28206  56.70526  1.000 56.42030  ? 230 LEU F N   1 
ATOM   3038 C CA  . LEU B 2 195 ? -52.85308 16.63178  56.11600  1.000 58.50984  ? 230 LEU F CA  1 
ATOM   3039 C C   . LEU B 2 195 ? -53.70998 17.63966  55.37762  1.000 63.42472  ? 230 LEU F C   1 
ATOM   3040 O O   . LEU B 2 195 ? -54.15102 17.37526  54.25229  1.000 72.91407  ? 230 LEU F O   1 
ATOM   3041 C CB  . LEU B 2 195 ? -53.68385 15.91599  57.17990  1.000 63.15487  ? 230 LEU F CB  1 
ATOM   3042 C CG  . LEU B 2 195 ? -54.98395 15.30671  56.64124  1.000 51.03253  ? 230 LEU F CG  1 
ATOM   3043 C CD1 . LEU B 2 195 ? -54.68414 14.26337  55.59046  1.000 46.04771  ? 230 LEU F CD1 1 
ATOM   3044 C CD2 . LEU B 2 195 ? -55.81340 14.70394  57.75850  1.000 58.61759  ? 230 LEU F CD2 1 
ATOM   3045 N N   . LEU B 2 196 ? -53.93458 18.81371  55.97477  1.000 59.26339  ? 231 LEU F N   1 
ATOM   3046 C CA  . LEU B 2 196 ? -54.79280 19.77383  55.28807  1.000 63.67381  ? 231 LEU F CA  1 
ATOM   3047 C C   . LEU B 2 196 ? -54.15206 20.25462  53.98915  1.000 69.72273  ? 231 LEU F C   1 
ATOM   3048 O O   . LEU B 2 196 ? -54.84153 20.40806  52.97370  1.000 73.42197  ? 231 LEU F O   1 
ATOM   3049 C CB  . LEU B 2 196 ? -55.12511 20.95296  56.20163  1.000 67.60399  ? 231 LEU F CB  1 
ATOM   3050 C CG  . LEU B 2 196 ? -55.73970 20.61113  57.55826  1.000 74.99037  ? 231 LEU F CG  1 
ATOM   3051 C CD1 . LEU B 2 196 ? -56.12914 21.87988  58.30609  1.000 83.34642  ? 231 LEU F CD1 1 
ATOM   3052 C CD2 . LEU B 2 196 ? -56.94936 19.71295  57.35423  1.000 70.23256  ? 231 LEU F CD2 1 
ATOM   3053 N N   . GLU B 2 197 ? -52.82981 20.45157  53.97920  1.000 65.38319  ? 232 GLU F N   1 
ATOM   3054 C CA  . GLU B 2 197 ? -52.19246 20.92306  52.74799  1.000 62.89566  ? 232 GLU F CA  1 
ATOM   3055 C C   . GLU B 2 197 ? -52.14124 19.84361  51.67204  1.000 63.18288  ? 232 GLU F C   1 
ATOM   3056 O O   . GLU B 2 197 ? -52.28039 20.15301  50.47786  1.000 74.36143  ? 232 GLU F O   1 
ATOM   3057 C CB  . GLU B 2 197 ? -50.79939 21.47422  53.03555  1.000 64.13430  ? 232 GLU F CB  1 
ATOM   3058 C CG  . GLU B 2 197 ? -50.82629 22.68295  53.95639  1.000 83.88673  ? 232 GLU F CG  1 
ATOM   3059 C CD  . GLU B 2 197 ? -51.32494 23.94209  53.25115  1.000 90.74636  ? 232 GLU F CD  1 
ATOM   3060 O OE1 . GLU B 2 197 ? -51.50541 23.90420  52.01302  1.000 100.06735 ? 232 GLU F OE1 1 
ATOM   3061 O OE2 . GLU B 2 197 ? -51.52885 24.97047  53.93537  1.000 87.48699  ? 232 GLU F OE2 1 
ATOM   3062 N N   . ILE B 2 198 ? -51.99624 18.57465  52.06014  1.000 55.78547  ? 233 ILE F N   1 
ATOM   3063 C CA  . ILE B 2 198 ? -51.99628 17.52522  51.04728  1.000 55.89261  ? 233 ILE F CA  1 
ATOM   3064 C C   . ILE B 2 198 ? -53.39102 17.36906  50.46271  1.000 66.53797  ? 233 ILE F C   1 
ATOM   3065 O O   . ILE B 2 198 ? -53.55028 17.18006  49.24977  1.000 80.59580  ? 233 ILE F O   1 
ATOM   3066 C CB  . ILE B 2 198 ? -51.46023 16.20188  51.61520  1.000 52.56630  ? 233 ILE F CB  1 
ATOM   3067 C CG1 . ILE B 2 198 ? -49.96462 16.30950  51.88023  1.000 59.07792  ? 233 ILE F CG1 1 
ATOM   3068 C CG2 . ILE B 2 198 ? -51.72153 15.06054  50.65448  1.000 57.04674  ? 233 ILE F CG2 1 
ATOM   3069 C CD1 . ILE B 2 198 ? -49.39745 15.07120  52.51664  1.000 66.93340  ? 233 ILE F CD1 1 
ATOM   3070 N N   . THR B 2 199 ? -54.42379 17.43222  51.31187  1.000 63.28496  ? 234 THR F N   1 
ATOM   3071 C CA  . THR B 2 199 ? -55.78746 17.38740  50.79361  1.000 63.77672  ? 234 THR F CA  1 
ATOM   3072 C C   . THR B 2 199 ? -56.06492 18.59169  49.90653  1.000 74.99984  ? 234 THR F C   1 
ATOM   3073 O O   . THR B 2 199 ? -56.79251 18.47696  48.91609  1.000 87.36047  ? 234 THR F O   1 
ATOM   3074 C CB  . THR B 2 199 ? -56.81197 17.32983  51.92807  1.000 70.01168  ? 234 THR F CB  1 
ATOM   3075 O OG1 . THR B 2 199 ? -56.70822 18.51385  52.72851  1.000 86.21494  ? 234 THR F OG1 1 
ATOM   3076 C CG2 . THR B 2 199 ? -56.60488 16.09635  52.79357  1.000 71.53606  ? 234 THR F CG2 1 
ATOM   3077 N N   . ARG B 2 200 ? -55.43968 19.73290  50.20501  1.000 75.63559  ? 235 ARG F N   1 
ATOM   3078 C CA  . ARG B 2 200 ? -55.62507 20.92328  49.38229  1.000 82.29214  ? 235 ARG F CA  1 
ATOM   3079 C C   . ARG B 2 200 ? -55.06524 20.70541  47.98321  1.000 78.09795  ? 235 ARG F C   1 
ATOM   3080 O O   . ARG B 2 200 ? -55.74985 20.95073  46.97281  1.000 82.38632  ? 235 ARG F O   1 
ATOM   3081 C CB  . ARG B 2 200 ? -54.89088 22.09351  50.03948  1.000 89.29487  ? 235 ARG F CB  1 
ATOM   3082 C CG  . ARG B 2 200 ? -55.30984 23.49557  49.65100  1.000 97.98673  ? 235 ARG F CG  1 
ATOM   3083 C CD  . ARG B 2 200 ? -56.58320 23.88735  50.36275  1.000 119.47263 ? 235 ARG F CD  1 
ATOM   3084 N NE  . ARG B 2 200 ? -57.02474 25.22998  50.00650  1.000 136.44538 ? 235 ARG F NE  1 
ATOM   3085 C CZ  . ARG B 2 200 ? -58.20624 25.73569  50.33308  1.000 129.36932 ? 235 ARG F CZ  1 
ATOM   3086 N NH1 . ARG B 2 200 ? -59.08968 25.03434  51.02364  1.000 137.06738 ? 235 ARG F NH1 1 
ATOM   3087 N NH2 . ARG B 2 200 ? -58.50199 26.98201  49.97431  1.000 114.29226 ? 235 ARG F NH2 1 
ATOM   3088 N N   . GLU B 2 201 ? -53.85141 20.14674  47.91027  1.000 71.93910  ? 236 GLU F N   1 
ATOM   3089 C CA  . GLU B 2 201 ? -53.23768 19.91801  46.60623  1.000 73.50288  ? 236 GLU F CA  1 
ATOM   3090 C C   . GLU B 2 201 ? -53.96625 18.82831  45.83416  1.000 79.31258  ? 236 GLU F C   1 
ATOM   3091 O O   . GLU B 2 201 ? -54.19845 18.97031  44.62874  1.000 84.78099  ? 236 GLU F O   1 
ATOM   3092 C CB  . GLU B 2 201 ? -51.75837 19.56739  46.76463  1.000 72.90465  ? 236 GLU F CB  1 
ATOM   3093 C CG  . GLU B 2 201 ? -50.95443 20.61390  47.51571  1.000 82.59307  ? 236 GLU F CG  1 
ATOM   3094 C CD  . GLU B 2 201 ? -49.47450 20.28067  47.59228  1.000 87.01674  ? 236 GLU F CD  1 
ATOM   3095 O OE1 . GLU B 2 201 ? -49.00814 19.41464  46.81892  1.000 79.69340  ? 236 GLU F OE1 1 
ATOM   3096 O OE2 . GLU B 2 201 ? -48.77797 20.88484  48.43550  1.000 88.48730  ? 236 GLU F OE2 1 
ATOM   3097 N N   . PHE B 2 202 ? -54.34456 17.73762  46.50157  1.000 82.74772  ? 237 PHE F N   1 
ATOM   3098 C CA  . PHE B 2 202 ? -55.02284 16.66584  45.78112  1.000 81.17592  ? 237 PHE F CA  1 
ATOM   3099 C C   . PHE B 2 202 ? -56.41935 17.07664  45.33009  1.000 82.51480  ? 237 PHE F C   1 
ATOM   3100 O O   . PHE B 2 202 ? -56.91297 16.56234  44.32154  1.000 91.45909  ? 237 PHE F O   1 
ATOM   3101 C CB  . PHE B 2 202 ? -55.09745 15.40226  46.63591  1.000 85.55603  ? 237 PHE F CB  1 
ATOM   3102 C CG  . PHE B 2 202 ? -53.88945 14.52452  46.53058  1.000 82.82431  ? 237 PHE F CG  1 
ATOM   3103 C CD1 . PHE B 2 202 ? -53.14155 14.49597  45.36734  1.000 84.98220  ? 237 PHE F CD1 1 
ATOM   3104 C CD2 . PHE B 2 202 ? -53.51922 13.70390  47.58038  1.000 83.33011  ? 237 PHE F CD2 1 
ATOM   3105 C CE1 . PHE B 2 202 ? -52.03758 13.67281  45.25776  1.000 86.70765  ? 237 PHE F CE1 1 
ATOM   3106 C CE2 . PHE B 2 202 ? -52.41517 12.88004  47.47772  1.000 83.29880  ? 237 PHE F CE2 1 
ATOM   3107 C CZ  . PHE B 2 202 ? -51.67570 12.86291  46.31313  1.000 81.22664  ? 237 PHE F CZ  1 
ATOM   3108 N N   . SER B 2 203 ? -57.07482 17.98713  46.05911  1.000 82.27620  ? 238 SER F N   1 
ATOM   3109 C CA  . SER B 2 203 ? -58.42116 18.41784  45.69421  1.000 91.97696  ? 238 SER F CA  1 
ATOM   3110 C C   . SER B 2 203 ? -58.43488 19.39232  44.52100  1.000 101.79806 ? 238 SER F C   1 
ATOM   3111 O O   . SER B 2 203 ? -59.26964 19.26036  43.61741  1.000 106.85626 ? 238 SER F O   1 
ATOM   3112 C CB  . SER B 2 203 ? -59.12064 19.04168  46.90243  1.000 97.03160  ? 238 SER F CB  1 
ATOM   3113 O OG  . SER B 2 203 ? -59.26369 18.10024  47.95106  1.000 108.04448 ? 238 SER F OG  1 
ATOM   3114 N N   . VAL B 2 204 ? -57.53588 20.38300  44.51470  1.000 103.35660 ? 239 VAL F N   1 
ATOM   3115 C CA  . VAL B 2 204 ? -57.58676 21.38015  43.44184  1.000 92.33995  ? 239 VAL F CA  1 
ATOM   3116 C C   . VAL B 2 204 ? -57.07934 20.86183  42.09537  1.000 87.56806  ? 239 VAL F C   1 
ATOM   3117 O O   . VAL B 2 204 ? -57.38547 21.46327  41.06041  1.000 98.53412  ? 239 VAL F O   1 
ATOM   3118 C CB  . VAL B 2 204 ? -56.83903 22.65917  43.85825  1.000 95.54536  ? 239 VAL F CB  1 
ATOM   3119 C CG1 . VAL B 2 204 ? -57.44587 23.22217  45.13573  1.000 111.12438 ? 239 VAL F CG1 1 
ATOM   3120 C CG2 . VAL B 2 204 ? -55.36848 22.37578  44.05333  1.000 96.46454  ? 239 VAL F CG2 1 
ATOM   3121 N N   . ASN B 2 205 ? -56.32315 19.76311  42.06995  1.000 89.03968  ? 240 ASN F N   1 
ATOM   3122 C CA  . ASN B 2 205 ? -55.72338 19.22502  40.85065  1.000 86.79242  ? 240 ASN F CA  1 
ATOM   3123 C C   . ASN B 2 205 ? -56.29575 17.86555  40.45942  1.000 83.46967  ? 240 ASN F C   1 
ATOM   3124 O O   . ASN B 2 205 ? -55.67515 17.14472  39.67059  1.000 74.40662  ? 240 ASN F O   1 
ATOM   3125 C CB  . ASN B 2 205 ? -54.20380 19.11523  40.99100  1.000 90.13974  ? 240 ASN F CB  1 
ATOM   3126 C CG  . ASN B 2 205 ? -53.52716 20.45834  41.16324  1.000 91.87515  ? 240 ASN F CG  1 
ATOM   3127 O OD1 . ASN B 2 205 ? -54.17602 21.46910  41.41440  1.000 91.11809  ? 240 ASN F OD1 1 
ATOM   3128 N ND2 . ASN B 2 205 ? -52.20858 20.47565  41.00710  1.000 94.47108  ? 240 ASN F ND2 1 
ATOM   3129 N N   . ALA B 2 206 ? -57.46691 17.50559  40.98975  1.000 88.30608  ? 241 ALA F N   1 
ATOM   3130 C CA  . ALA B 2 206 ? -58.15654 16.26944  40.61302  1.000 85.78630  ? 241 ALA F CA  1 
ATOM   3131 C C   . ALA B 2 206 ? -57.26743 15.05312  40.86343  1.000 88.57237  ? 241 ALA F C   1 
ATOM   3132 O O   . ALA B 2 206 ? -57.18799 14.13114  40.04716  1.000 88.11503  ? 241 ALA F O   1 
ATOM   3133 C CB  . ALA B 2 206 ? -58.64173 16.31022  39.16233  1.000 88.95864  ? 241 ALA F CB  1 
ATOM   3134 N N   . GLY B 2 207 ? -56.58442 15.07030  42.01282  1.000 94.70842  ? 242 GLY F N   1 
ATOM   3135 C CA  . GLY B 2 207 ? -55.77242 13.96706  42.48161  1.000 89.21978  ? 242 GLY F CA  1 
ATOM   3136 C C   . GLY B 2 207 ? -54.38402 13.81040  41.90080  1.000 88.56524  ? 242 GLY F C   1 
ATOM   3137 O O   . GLY B 2 207 ? -53.63191 12.95724  42.38831  1.000 92.28424  ? 242 GLY F O   1 
ATOM   3138 N N   . VAL B 2 208 ? -53.99203 14.58743  40.89653  1.000 86.41875  ? 243 VAL F N   1 
ATOM   3139 C CA  . VAL B 2 208 ? -52.66223 14.44304  40.30735  1.000 84.78434  ? 243 VAL F CA  1 
ATOM   3140 C C   . VAL B 2 208 ? -51.91932 15.77180  40.35147  1.000 81.33545  ? 243 VAL F C   1 
ATOM   3141 O O   . VAL B 2 208 ? -52.26941 16.71669  39.63327  1.000 92.00639  ? 243 VAL F O   1 
ATOM   3142 C CB  . VAL B 2 208 ? -52.73149 13.91486  38.87108  1.000 87.91820  ? 243 VAL F CB  1 
ATOM   3143 C CG1 . VAL B 2 208 ? -51.33171 13.65499  38.36097  1.000 97.01092  ? 243 VAL F CG1 1 
ATOM   3144 C CG2 . VAL B 2 208 ? -53.56580 12.65291  38.81617  1.000 91.29284  ? 243 VAL F CG2 1 
ATOM   3145 N N   . THR B 2 209 ? -50.90905 15.85244  41.21217  1.000 75.26870  ? 244 THR F N   1 
ATOM   3146 C CA  . THR B 2 209 ? -50.13526 17.06763  41.41592  1.000 80.98924  ? 244 THR F CA  1 
ATOM   3147 C C   . THR B 2 209 ? -48.69901 16.85466  40.96085  1.000 81.99830  ? 244 THR F C   1 
ATOM   3148 O O   . THR B 2 209 ? -48.13172 15.77257  41.13548  1.000 78.59384  ? 244 THR F O   1 
ATOM   3149 C CB  . THR B 2 209 ? -50.14327 17.50435  42.87495  1.000 91.06851  ? 244 THR F CB  1 
ATOM   3150 O OG1 . THR B 2 209 ? -49.40400 16.56131  43.65909  1.000 96.73881  ? 244 THR F OG1 1 
ATOM   3151 C CG2 . THR B 2 209 ? -51.56425 17.57078  43.37515  1.000 92.75173  ? 244 THR F CG2 1 
ATOM   3152 N N   . THR B 2 210 ? -48.12448 17.89003  40.37537  1.000 84.73721  ? 245 THR F N   1 
ATOM   3153 C CA  . THR B 2 210 ? -46.72575 17.93317  39.95542  1.000 87.42332  ? 245 THR F CA  1 
ATOM   3154 C C   . THR B 2 210 ? -46.28054 19.38955  39.84290  1.000 83.87037  ? 245 THR F C   1 
ATOM   3155 O O   . THR B 2 210 ? -47.00548 20.21541  39.27502  1.000 85.48126  ? 245 THR F O   1 
ATOM   3156 C CB  . THR B 2 210 ? -46.50206 17.18377  38.64556  1.000 89.02067  ? 245 THR F CB  1 
ATOM   3157 O OG1 . THR B 2 210 ? -45.15690 17.40955  38.20070  1.000 84.31041  ? 245 THR F OG1 1 
ATOM   3158 C CG2 . THR B 2 210 ? -47.47095 17.66557  37.59978  1.000 97.30004  ? 245 THR F CG2 1 
ATOM   3159 N N   . PRO B 2 211 ? -45.10156 19.75709  40.37444  1.000 84.38325  ? 246 PRO F N   1 
ATOM   3160 C CA  . PRO B 2 211 ? -44.10852 18.90556  41.04397  1.000 91.69521  ? 246 PRO F CA  1 
ATOM   3161 C C   . PRO B 2 211 ? -44.54572 18.38682  42.40048  1.000 92.18026  ? 246 PRO F C   1 
ATOM   3162 O O   . PRO B 2 211 ? -45.57051 18.80495  42.94067  1.000 95.91726  ? 246 PRO F O   1 
ATOM   3163 C CB  . PRO B 2 211 ? -42.89794 19.83619  41.20909  1.000 94.78148  ? 246 PRO F CB  1 
ATOM   3164 C CG  . PRO B 2 211 ? -43.14613 20.97802  40.28636  1.000 95.12594  ? 246 PRO F CG  1 
ATOM   3165 C CD  . PRO B 2 211 ? -44.62814 21.14428  40.26389  1.000 86.03771  ? 246 PRO F CD  1 
ATOM   3166 N N   . VAL B 2 212 ? -43.76195 17.46623  42.94924  1.000 82.52312  ? 247 VAL F N   1 
ATOM   3167 C CA  . VAL B 2 212 ? -44.07187 16.89613  44.25235  1.000 80.92104  ? 247 VAL F CA  1 
ATOM   3168 C C   . VAL B 2 212 ? -43.52571 17.84119  45.31846  1.000 85.15722  ? 247 VAL F C   1 
ATOM   3169 O O   . VAL B 2 212 ? -42.31157 18.00339  45.45942  1.000 90.67359  ? 247 VAL F O   1 
ATOM   3170 C CB  . VAL B 2 212 ? -43.47716 15.49230  44.39114  1.000 85.17568  ? 247 VAL F CB  1 
ATOM   3171 C CG1 . VAL B 2 212 ? -43.73509 14.93501  45.77883  1.000 101.06985 ? 247 VAL F CG1 1 
ATOM   3172 C CG2 . VAL B 2 212 ? -44.01351 14.57948  43.29255  1.000 75.05318  ? 247 VAL F CG2 1 
ATOM   3173 N N   . SER B 2 213 ? -44.42426 18.45787  46.07910  1.000 75.39190  ? 248 SER F N   1 
ATOM   3174 C CA  . SER B 2 213 ? -44.04133 19.43043  47.08911  1.000 79.96260  ? 248 SER F CA  1 
ATOM   3175 C C   . SER B 2 213 ? -43.47608 18.73578  48.32875  1.000 86.07482  ? 248 SER F C   1 
ATOM   3176 O O   . SER B 2 213 ? -43.57269 17.51614  48.49147  1.000 87.58870  ? 248 SER F O   1 
ATOM   3177 C CB  . SER B 2 213 ? -45.23921 20.30183  47.45507  1.000 80.59659  ? 248 SER F CB  1 
ATOM   3178 O OG  . SER B 2 213 ? -46.27650 19.51113  48.00615  1.000 82.96725  ? 248 SER F OG  1 
ATOM   3179 N N   . THR B 2 214 ? -42.87228 19.53598  49.21674  1.000 89.47001  ? 249 THR F N   1 
ATOM   3180 C CA  . THR B 2 214 ? -42.37977 18.99870  50.48287  1.000 99.02332  ? 249 THR F CA  1 
ATOM   3181 C C   . THR B 2 214 ? -43.52624 18.55171  51.37971  1.000 92.45036  ? 249 THR F C   1 
ATOM   3182 O O   . THR B 2 214 ? -43.31280 17.73951  52.28617  1.000 96.73459  ? 249 THR F O   1 
ATOM   3183 C CB  . THR B 2 214 ? -41.51412 20.03009  51.22019  1.000 111.43457 ? 249 THR F CB  1 
ATOM   3184 O OG1 . THR B 2 214 ? -40.77818 20.81547  50.27361  1.000 127.79818 ? 249 THR F OG1 1 
ATOM   3185 C CG2 . THR B 2 214 ? -40.52439 19.34452  52.17130  1.000 101.00010 ? 249 THR F CG2 1 
ATOM   3186 N N   . TYR B 2 215 ? -44.73807 19.05667  51.13991  1.000 87.41512  ? 250 TYR F N   1 
ATOM   3187 C CA  . TYR B 2 215 ? -45.89416 18.54864  51.86464  1.000 79.38865  ? 250 TYR F CA  1 
ATOM   3188 C C   . TYR B 2 215 ? -46.20067 17.13244  51.40883  1.000 76.06947  ? 250 TYR F C   1 
ATOM   3189 O O   . TYR B 2 215 ? -46.48624 16.24888  52.22490  1.000 81.20772  ? 250 TYR F O   1 
ATOM   3190 C CB  . TYR B 2 215 ? -47.11496 19.44004  51.61468  1.000 78.06895  ? 250 TYR F CB  1 
ATOM   3191 C CG  . TYR B 2 215 ? -47.04882 20.83246  52.20579  1.000 83.54988  ? 250 TYR F CG  1 
ATOM   3192 C CD1 . TYR B 2 215 ? -46.40465 21.07414  53.41263  1.000 87.08492  ? 250 TYR F CD1 1 
ATOM   3193 C CD2 . TYR B 2 215 ? -47.64327 21.90915  51.55248  1.000 83.31946  ? 250 TYR F CD2 1 
ATOM   3194 C CE1 . TYR B 2 215 ? -46.34574 22.35253  53.94911  1.000 90.11215  ? 250 TYR F CE1 1 
ATOM   3195 C CE2 . TYR B 2 215 ? -47.59160 23.18598  52.07953  1.000 88.70811  ? 250 TYR F CE2 1 
ATOM   3196 C CZ  . TYR B 2 215 ? -46.94356 23.40369  53.27600  1.000 91.24597  ? 250 TYR F CZ  1 
ATOM   3197 O OH  . TYR B 2 215 ? -46.89500 24.67725  53.79724  1.000 94.20951  ? 250 TYR F OH  1 
ATOM   3198 N N   . MET B 2 216 ? -46.11159 16.90411  50.10001  1.000 72.06782  ? 251 MET F N   1 
ATOM   3199 C CA  . MET B 2 216 ? -46.29127 15.57313  49.53946  1.000 67.20883  ? 251 MET F CA  1 
ATOM   3200 C C   . MET B 2 216 ? -45.16143 14.62710  49.94513  1.000 70.11549  ? 251 MET F C   1 
ATOM   3201 O O   . MET B 2 216 ? -45.40723 13.44947  50.22839  1.000 72.78931  ? 251 MET F O   1 
ATOM   3202 C CB  . MET B 2 216 ? -46.37218 15.69166  48.01816  1.000 71.79973  ? 251 MET F CB  1 
ATOM   3203 C CG  . MET B 2 216 ? -47.58961 16.46600  47.50944  1.000 77.77770  ? 251 MET F CG  1 
ATOM   3204 S SD  . MET B 2 216 ? -49.18421 15.63639  47.56129  1.000 72.71570  ? 251 MET F SD  1 
ATOM   3205 C CE  . MET B 2 216 ? -48.67843 13.93107  47.51663  1.000 69.53258  ? 251 MET F CE  1 
ATOM   3206 N N   . LEU B 2 217 ? -43.91729 15.11713  49.96953  1.000 73.94751  ? 252 LEU F N   1 
ATOM   3207 C CA  . LEU B 2 217 ? -42.75456 14.27594  50.27404  1.000 84.62481  ? 252 LEU F CA  1 
ATOM   3208 C C   . LEU B 2 217 ? -41.62958 15.12962  50.85076  1.000 84.77001  ? 252 LEU F C   1 
ATOM   3209 O O   . LEU B 2 217 ? -41.08076 15.98206  50.14574  1.000 80.18933  ? 252 LEU F O   1 
ATOM   3210 C CB  . LEU B 2 217 ? -42.28283 13.51941  49.03351  1.000 85.23161  ? 252 LEU F CB  1 
ATOM   3211 C CG  . LEU B 2 217 ? -41.36761 12.32636  49.32709  1.000 85.80555  ? 252 LEU F CG  1 
ATOM   3212 C CD1 . LEU B 2 217 ? -42.10561 11.30206  50.16761  1.000 85.53856  ? 252 LEU F CD1 1 
ATOM   3213 C CD2 . LEU B 2 217 ? -40.83995 11.68656  48.04938  1.000 80.37981  ? 252 LEU F CD2 1 
ATOM   3214 N N   . THR B 2 218 ? -41.27481 14.89810  52.11459  1.000 85.61616  ? 253 THR F N   1 
ATOM   3215 C CA  . THR B 2 218 ? -40.22035 15.68094  52.74973  1.000 91.76823  ? 253 THR F CA  1 
ATOM   3216 C C   . THR B 2 218 ? -38.85679 15.40693  52.11851  1.000 93.46367  ? 253 THR F C   1 
ATOM   3217 O O   . THR B 2 218 ? -38.61175 14.34408  51.54107  1.000 90.27798  ? 253 THR F O   1 
ATOM   3218 C CB  . THR B 2 218 ? -40.15782 15.35789  54.24275  1.000 95.77704  ? 253 THR F CB  1 
ATOM   3219 O OG1 . THR B 2 218 ? -41.48913 15.23274  54.75346  1.000 100.21882 ? 253 THR F OG1 1 
ATOM   3220 C CG2 . THR B 2 218 ? -39.43011 16.45252  55.01147  1.000 89.71283  ? 253 THR F CG2 1 
ATOM   3221 N N   . ASN B 2 219 ? -37.96661 16.39946  52.23252  1.000 94.63038  ? 254 ASN F N   1 
ATOM   3222 C CA  . ASN B 2 219 ? -36.59625 16.25589  51.74788  1.000 96.46434  ? 254 ASN F CA  1 
ATOM   3223 C C   . ASN B 2 219 ? -35.88154 15.07546  52.39028  1.000 94.08823  ? 254 ASN F C   1 
ATOM   3224 O O   . ASN B 2 219 ? -35.11303 14.36854  51.72512  1.000 94.07879  ? 254 ASN F O   1 
ATOM   3225 C CB  . ASN B 2 219 ? -35.82172 17.54223  52.00876  1.000 99.75338  ? 254 ASN F CB  1 
ATOM   3226 C CG  . ASN B 2 219 ? -36.30827 18.68394  51.15922  1.000 104.91269 ? 254 ASN F CG  1 
ATOM   3227 O OD1 . ASN B 2 219 ? -36.32526 18.59778  49.93168  1.000 107.23162 ? 254 ASN F OD1 1 
ATOM   3228 N ND2 . ASN B 2 219 ? -36.71085 19.76885  51.80759  1.000 107.36433 ? 254 ASN F ND2 1 
ATOM   3229 N N   . SER B 2 220 ? -36.12691 14.83885  53.68062  1.000 88.73282  ? 255 SER F N   1 
ATOM   3230 C CA  . SER B 2 220 ? -35.54527 13.66826  54.32577  1.000 99.24996  ? 255 SER F CA  1 
ATOM   3231 C C   . SER B 2 220 ? -36.09247 12.39020  53.70992  1.000 102.69748 ? 255 SER F C   1 
ATOM   3232 O O   . SER B 2 220 ? -35.33632 11.45349  53.40959  1.000 103.11678 ? 255 SER F O   1 
ATOM   3233 C CB  . SER B 2 220 ? -35.81988 13.71325  55.82951  1.000 110.54809 ? 255 SER F CB  1 
ATOM   3234 O OG  . SER B 2 220 ? -35.39428 12.52258  56.46874  1.000 133.97756 ? 255 SER F OG  1 
ATOM   3235 N N   . GLU B 2 221 ? -37.39960 12.36638  53.44763  1.000 103.04112 ? 256 GLU F N   1 
ATOM   3236 C CA  . GLU B 2 221 ? -38.00213 11.19420  52.83825  1.000 101.65550 ? 256 GLU F CA  1 
ATOM   3237 C C   . GLU B 2 221 ? -37.57756 11.06352  51.38512  1.000 94.38622  ? 256 GLU F C   1 
ATOM   3238 O O   . GLU B 2 221 ? -37.39290 9.94587   50.89752  1.000 94.14383  ? 256 GLU F O   1 
ATOM   3239 C CB  . GLU B 2 221 ? -39.51923 11.29172  52.97469  1.000 98.99992  ? 256 GLU F CB  1 
ATOM   3240 C CG  . GLU B 2 221 ? -39.95666 11.53880  54.41334  1.000 101.04895 ? 256 GLU F CG  1 
ATOM   3241 C CD  . GLU B 2 221 ? -41.41468 11.92091  54.53529  1.000 96.31661  ? 256 GLU F CD  1 
ATOM   3242 O OE1 . GLU B 2 221 ? -42.04685 12.19828  53.49442  1.000 86.77278  ? 256 GLU F OE1 1 
ATOM   3243 O OE2 . GLU B 2 221 ? -41.92373 11.95544  55.67608  1.000 104.65217 ? 256 GLU F OE2 1 
ATOM   3244 N N   . LEU B 2 222 ? -37.35767 12.18416  50.69433  1.000 89.67434  ? 257 LEU F N   1 
ATOM   3245 C CA  . LEU B 2 222 ? -36.95431 12.08789  49.29879  1.000 88.97861  ? 257 LEU F CA  1 
ATOM   3246 C C   . LEU B 2 222 ? -35.54373 11.53159  49.19237  1.000 95.12226  ? 257 LEU F C   1 
ATOM   3247 O O   . LEU B 2 222 ? -35.27409 10.65225  48.37019  1.000 99.81412  ? 257 LEU F O   1 
ATOM   3248 C CB  . LEU B 2 222 ? -37.02900 13.45404  48.62054  1.000 86.82352  ? 257 LEU F CB  1 
ATOM   3249 C CG  . LEU B 2 222 ? -36.55906 13.40913  47.16437  1.000 85.21939  ? 257 LEU F CG  1 
ATOM   3250 C CD1 . LEU B 2 222 ? -37.41118 12.43552  46.36804  1.000 82.54219  ? 257 LEU F CD1 1 
ATOM   3251 C CD2 . LEU B 2 222 ? -36.55990 14.79175  46.52951  1.000 91.29824  ? 257 LEU F CD2 1 
ATOM   3252 N N   . LEU B 2 223 ? -34.62119 12.04615  50.00667  1.000 93.10986  ? 258 LEU F N   1 
ATOM   3253 C CA  . LEU B 2 223 ? -33.26219 11.52594  49.95832  1.000 85.53780  ? 258 LEU F CA  1 
ATOM   3254 C C   . LEU B 2 223 ? -33.20243 10.07057  50.40330  1.000 91.06833  ? 258 LEU F C   1 
ATOM   3255 O O   . LEU B 2 223 ? -32.48745 9.26877   49.79467  1.000 97.20334  ? 258 LEU F O   1 
ATOM   3256 C CB  . LEU B 2 223 ? -32.31767 12.40058  50.78003  1.000 94.45708  ? 258 LEU F CB  1 
ATOM   3257 C CG  . LEU B 2 223 ? -32.10506 13.77138  50.13591  1.000 97.58568  ? 258 LEU F CG  1 
ATOM   3258 C CD1 . LEU B 2 223 ? -31.25357 14.68177  51.01116  1.000 111.73269 ? 258 LEU F CD1 1 
ATOM   3259 C CD2 . LEU B 2 223 ? -31.47795 13.59449  48.75367  1.000 82.80181  ? 258 LEU F CD2 1 
ATOM   3260 N N   . SER B 2 224 ? -33.96091 9.69288   51.44077  1.000 91.53744  ? 259 SER F N   1 
ATOM   3261 C CA  . SER B 2 224 ? -33.98259 8.28099   51.81679  1.000 92.37684  ? 259 SER F CA  1 
ATOM   3262 C C   . SER B 2 224 ? -34.61494 7.40263   50.73987  1.000 92.80936  ? 259 SER F C   1 
ATOM   3263 O O   . SER B 2 224 ? -34.14813 6.27819   50.50298  1.000 99.91686  ? 259 SER F O   1 
ATOM   3264 C CB  . SER B 2 224 ? -34.71839 8.10624   53.14641  1.000 92.37909  ? 259 SER F CB  1 
ATOM   3265 O OG  . SER B 2 224 ? -34.89512 6.73539   53.45682  1.000 111.00424 ? 259 SER F OG  1 
ATOM   3266 N N   . LEU B 2 225 ? -35.60735 7.91990   50.01362  1.000 91.77231  ? 260 LEU F N   1 
ATOM   3267 C CA  . LEU B 2 225 ? -36.21305 7.12630   48.95365  1.000 97.90730  ? 260 LEU F CA  1 
ATOM   3268 C C   . LEU B 2 225 ? -35.27074 7.00442   47.76759  1.000 104.73468 ? 260 LEU F C   1 
ATOM   3269 O O   . LEU B 2 225 ? -35.23662 5.96356   47.10000  1.000 105.84887 ? 260 LEU F O   1 
ATOM   3270 C CB  . LEU B 2 225 ? -37.54411 7.74913   48.53902  1.000 92.13630  ? 260 LEU F CB  1 
ATOM   3271 C CG  . LEU B 2 225 ? -38.38796 6.96751   47.53648  1.000 92.06156  ? 260 LEU F CG  1 
ATOM   3272 C CD1 . LEU B 2 225 ? -38.52647 5.50855   47.96211  1.000 98.77818  ? 260 LEU F CD1 1 
ATOM   3273 C CD2 . LEU B 2 225 ? -39.74959 7.62427   47.38520  1.000 76.70879  ? 260 LEU F CD2 1 
ATOM   3274 N N   . ILE B 2 226 ? -34.50325 8.06052   47.48553  1.000 104.64989 ? 261 ILE F N   1 
ATOM   3275 C CA  . ILE B 2 226 ? -33.52695 7.98083   46.40749  1.000 99.11153  ? 261 ILE F CA  1 
ATOM   3276 C C   . ILE B 2 226 ? -32.45850 6.97494   46.79274  1.000 105.43406 ? 261 ILE F C   1 
ATOM   3277 O O   . ILE B 2 226 ? -32.02487 6.15565   45.97429  1.000 110.71396 ? 261 ILE F O   1 
ATOM   3278 C CB  . ILE B 2 226 ? -32.94116 9.37442   46.10655  1.000 96.92700  ? 261 ILE F CB  1 
ATOM   3279 C CG1 . ILE B 2 226 ? -34.01920 10.28296  45.51681  1.000 93.57212  ? 261 ILE F CG1 1 
ATOM   3280 C CG2 . ILE B 2 226 ? -31.76213 9.28920   45.14494  1.000 97.29166  ? 261 ILE F CG2 1 
ATOM   3281 C CD1 . ILE B 2 226 ? -33.48137 11.54741  44.91640  1.000 91.92217  ? 261 ILE F CD1 1 
ATOM   3282 N N   . ASN B 2 227 ? -32.03275 7.01561   48.06049  1.000 106.89030 ? 262 ASN F N   1 
ATOM   3283 C CA  . ASN B 2 227 ? -30.95901 6.15283   48.52530  1.000 108.68479 ? 262 ASN F CA  1 
ATOM   3284 C C   . ASN B 2 227 ? -31.38419 4.69339   48.48435  1.000 112.29764 ? 262 ASN F C   1 
ATOM   3285 O O   . ASN B 2 227 ? -30.53521 3.80551   48.34442  1.000 108.36740 ? 262 ASN F O   1 
ATOM   3286 C CB  . ASN B 2 227 ? -30.53595 6.55895   49.93549  1.000 106.65292 ? 262 ASN F CB  1 
ATOM   3287 C CG  . ASN B 2 227 ? -29.22519 5.93422   50.35030  1.000 110.18609 ? 262 ASN F CG  1 
ATOM   3288 O OD1 . ASN B 2 227 ? -28.37555 5.63413   49.51306  1.000 113.45861 ? 262 ASN F OD1 1 
ATOM   3289 N ND2 . ASN B 2 227 ? -29.04312 5.75353   51.65201  1.000 112.14773 ? 262 ASN F ND2 1 
ATOM   3290 N N   . ASP B 2 228 ? -32.68836 4.42596   48.60954  1.000 117.34271 ? 263 ASP F N   1 
ATOM   3291 C CA  . ASP B 2 228 ? -33.17015 3.05251   48.66818  1.000 116.44252 ? 263 ASP F CA  1 
ATOM   3292 C C   . ASP B 2 228 ? -33.59550 2.51172   47.30123  1.000 112.71220 ? 263 ASP F C   1 
ATOM   3293 O O   . ASP B 2 228 ? -34.21143 1.44326   47.23857  1.000 116.25485 ? 263 ASP F O   1 
ATOM   3294 C CB  . ASP B 2 228 ? -34.34181 2.94520   49.65486  1.000 117.22428 ? 263 ASP F CB  1 
ATOM   3295 C CG  . ASP B 2 228 ? -33.97410 3.39593   51.06527  1.000 115.75851 ? 263 ASP F CG  1 
ATOM   3296 O OD1 . ASP B 2 228 ? -32.78250 3.33208   51.43163  1.000 116.30917 ? 263 ASP F OD1 1 
ATOM   3297 O OD2 . ASP B 2 228 ? -34.88152 3.83268   51.80624  1.000 116.95643 ? 263 ASP F OD2 1 
ATOM   3298 N N   . MET B 2 229 ? -33.27193 3.25506   46.15474  1.000 116.69901 ? 264 MET F N   1 
ATOM   3299 C CA  . MET B 2 229 ? -33.72429 2.83630   44.83217  1.000 126.31204 ? 264 MET F CA  1 
ATOM   3300 C C   . MET B 2 229 ? -32.77005 1.81946   44.21031  1.000 133.92229 ? 264 MET F C   1 
ATOM   3301 O O   . MET B 2 229 ? -31.56240 1.84926   44.47261  1.000 130.19140 ? 264 MET F O   1 
ATOM   3302 C CB  . MET B 2 229 ? -33.86889 4.02591   43.88034  1.000 123.37460 ? 264 MET F CB  1 
ATOM   3303 C CG  . MET B 2 229 ? -35.11415 4.87603   44.06198  1.000 116.19086 ? 264 MET F CG  1 
ATOM   3304 S SD  . MET B 2 229 ? -35.24994 6.11559   42.75288  1.000 129.53968 ? 264 MET F SD  1 
ATOM   3305 C CE  . MET B 2 229 ? -35.70237 7.56486   43.69128  1.000 120.40143 ? 264 MET F CE  1 
ATOM   3306 N N   . PRO B 2 230 ? -33.29604 0.90487   43.38115  1.000 133.71261 ? 265 PRO F N   1 
ATOM   3307 C CA  . PRO B 2 230 ? -32.45232 -0.05445  42.64082  1.000 132.36592 ? 265 PRO F CA  1 
ATOM   3308 C C   . PRO B 2 230 ? -31.79418 0.58602   41.42048  1.000 128.48901 ? 265 PRO F C   1 
ATOM   3309 O O   . PRO B 2 230 ? -31.98815 0.16510   40.27614  1.000 128.68296 ? 265 PRO F O   1 
ATOM   3310 C CB  . PRO B 2 230 ? -33.45967 -1.14791  42.26432  1.000 134.95944 ? 265 PRO F CB  1 
ATOM   3311 C CG  . PRO B 2 230 ? -34.74880 -0.41705  42.11293  1.000 129.12829 ? 265 PRO F CG  1 
ATOM   3312 C CD  . PRO B 2 230 ? -34.73341 0.66086   43.16373  1.000 127.14858 ? 265 PRO F CD  1 
ATOM   3313 N N   . ILE B 2 231 ? -30.99958 1.62682   41.67049  1.000 131.88131 ? 266 ILE F N   1 
ATOM   3314 C CA  . ILE B 2 231 ? -30.27210 2.36012   40.64355  1.000 132.39728 ? 266 ILE F CA  1 
ATOM   3315 C C   . ILE B 2 231 ? -28.80911 2.45590   41.05253  1.000 134.34725 ? 266 ILE F C   1 
ATOM   3316 O O   . ILE B 2 231 ? -28.43908 2.17602   42.19397  1.000 129.22432 ? 266 ILE F O   1 
ATOM   3317 C CB  . ILE B 2 231 ? -30.84894 3.77037   40.40759  1.000 134.80091 ? 266 ILE F CB  1 
ATOM   3318 C CG1 . ILE B 2 231 ? -30.88466 4.55806   41.72343  1.000 131.54136 ? 266 ILE F CG1 1 
ATOM   3319 C CG2 . ILE B 2 231 ? -32.23039 3.66936   39.79891  1.000 129.80568 ? 266 ILE F CG2 1 
ATOM   3320 C CD1 . ILE B 2 231 ? -31.41567 5.98139   41.59618  1.000 125.60025 ? 266 ILE F CD1 1 
ATOM   3321 N N   . THR B 2 232 ? -27.97223 2.84981   40.09476  1.000 132.70121 ? 267 THR F N   1 
ATOM   3322 C CA  . THR B 2 232 ? -26.54748 2.92028   40.36441  1.000 129.75672 ? 267 THR F CA  1 
ATOM   3323 C C   . THR B 2 232 ? -26.26114 4.04516   41.35758  1.000 124.34306 ? 267 THR F C   1 
ATOM   3324 O O   . THR B 2 232 ? -27.06748 4.95749   41.56028  1.000 127.57931 ? 267 THR F O   1 
ATOM   3325 C CB  . THR B 2 232 ? -25.76501 3.14543   39.06939  1.000 126.44535 ? 267 THR F CB  1 
ATOM   3326 O OG1 . THR B 2 232 ? -25.93814 4.49898   38.63189  1.000 122.03401 ? 267 THR F OG1 1 
ATOM   3327 C CG2 . THR B 2 232 ? -26.25940 2.20355   37.98033  1.000 124.11963 ? 267 THR F CG2 1 
ATOM   3328 N N   . ASN B 2 233 ? -25.08242 3.97302   41.97511  1.000 117.36417 ? 268 ASN F N   1 
ATOM   3329 C CA  . ASN B 2 233 ? -24.66219 5.01805   42.90198  1.000 123.11939 ? 268 ASN F CA  1 
ATOM   3330 C C   . ASN B 2 233 ? -24.42470 6.35204   42.20711  1.000 126.00810 ? 268 ASN F C   1 
ATOM   3331 O O   . ASN B 2 233 ? -24.67299 7.40754   42.80485  1.000 126.30077 ? 268 ASN F O   1 
ATOM   3332 C CB  . ASN B 2 233 ? -23.42077 4.56976   43.66690  1.000 126.13794 ? 268 ASN F CB  1 
ATOM   3333 C CG  . ASN B 2 233 ? -23.76973 3.76669   44.90506  1.000 129.69142 ? 268 ASN F CG  1 
ATOM   3334 O OD1 . ASN B 2 233 ? -24.94445 3.53631   45.19852  1.000 130.17449 ? 268 ASN F OD1 1 
ATOM   3335 N ND2 . ASN B 2 233 ? -22.75245 3.33621   45.63776  1.000 121.37428 ? 268 ASN F ND2 1 
ATOM   3336 N N   . ASP B 2 234 ? -23.99244 6.33604   40.94292  1.000 130.67637 ? 269 ASP F N   1 
ATOM   3337 C CA  . ASP B 2 234 ? -23.86868 7.59636   40.21916  1.000 133.83998 ? 269 ASP F CA  1 
ATOM   3338 C C   . ASP B 2 234 ? -25.23440 8.20829   39.96384  1.000 126.59502 ? 269 ASP F C   1 
ATOM   3339 O O   . ASP B 2 234 ? -25.38037 9.43879   39.95865  1.000 116.97609 ? 269 ASP F O   1 
ATOM   3340 C CB  . ASP B 2 234 ? -23.15726 7.37101   38.88492  1.000 134.93165 ? 269 ASP F CB  1 
ATOM   3341 C CG  . ASP B 2 234 ? -21.80115 6.72034   39.04745  1.000 135.55427 ? 269 ASP F CG  1 
ATOM   3342 O OD1 . ASP B 2 234 ? -21.62996 5.92782   39.99738  1.000 134.13484 ? 269 ASP F OD1 1 
ATOM   3343 O OD2 . ASP B 2 234 ? -20.90431 7.00956   38.22891  1.000 136.24095 ? 269 ASP F OD2 1 
ATOM   3344 N N   . GLN B 2 235 ? -26.26679 7.37393   39.92299  1.000 128.50230 ? 270 GLN F N   1 
ATOM   3345 C CA  . GLN B 2 235 ? -27.60025 7.89209   39.69234  1.000 128.53644 ? 270 GLN F CA  1 
ATOM   3346 C C   . GLN B 2 235 ? -28.21261 8.38957   40.99201  1.000 120.97687 ? 270 GLN F C   1 
ATOM   3347 O O   . GLN B 2 235 ? -28.93623 9.39499   40.99149  1.000 115.17644 ? 270 GLN F O   1 
ATOM   3348 C CB  . GLN B 2 235 ? -28.44280 6.77205   39.07834  1.000 129.24342 ? 270 GLN F CB  1 
ATOM   3349 C CG  . GLN B 2 235 ? -29.79470 7.14780   38.52547  1.000 133.43720 ? 270 GLN F CG  1 
ATOM   3350 C CD  . GLN B 2 235 ? -30.39135 6.01933   37.69828  1.000 133.14813 ? 270 GLN F CD  1 
ATOM   3351 O OE1 . GLN B 2 235 ? -29.75341 4.98530   37.48601  1.000 129.70075 ? 270 GLN F OE1 1 
ATOM   3352 N NE2 . GLN B 2 235 ? -31.61943 6.21046   37.23219  1.000 131.53744 ? 270 GLN F NE2 1 
ATOM   3353 N N   . LYS B 2 236 ? -27.86257 7.76413   42.11935  1.000 120.70504 ? 271 LYS F N   1 
ATOM   3354 C CA  . LYS B 2 236 ? -28.35673 8.27485   43.38782  1.000 118.98007 ? 271 LYS F CA  1 
ATOM   3355 C C   . LYS B 2 236 ? -27.69468 9.60338   43.71548  1.000 117.66246 ? 271 LYS F C   1 
ATOM   3356 O O   . LYS B 2 236 ? -28.35725 10.53639  44.18190  1.000 114.71609 ? 271 LYS F O   1 
ATOM   3357 C CB  . LYS B 2 236 ? -28.06757 7.26294   44.49796  1.000 112.71096 ? 271 LYS F CB  1 
ATOM   3358 C CG  . LYS B 2 236 ? -28.77548 5.92366   44.36323  1.000 114.87618 ? 271 LYS F CG  1 
ATOM   3359 C CD  . LYS B 2 236 ? -28.38009 4.99574   45.50712  1.000 115.81457 ? 271 LYS F CD  1 
ATOM   3360 C CE  . LYS B 2 236 ? -29.03804 3.63318   45.38938  1.000 110.29907 ? 271 LYS F CE  1 
ATOM   3361 N NZ  . LYS B 2 236 ? -28.61930 2.74407   46.50515  1.000 101.46536 ? 271 LYS F NZ  1 
ATOM   3362 N N   . LYS B 2 237 ? -26.39102 9.71970   43.42597  1.000 116.86042 ? 272 LYS F N   1 
ATOM   3363 C CA  . LYS B 2 237 ? -25.69860 10.98902  43.62070  1.000 111.32195 ? 272 LYS F CA  1 
ATOM   3364 C C   . LYS B 2 237 ? -26.22083 12.05847  42.67621  1.000 110.05268 ? 272 LYS F C   1 
ATOM   3365 O O   . LYS B 2 237 ? -26.31226 13.23704  43.05411  1.000 114.23488 ? 272 LYS F O   1 
ATOM   3366 C CB  . LYS B 2 237 ? -24.19547 10.79510  43.44919  1.000 116.35365 ? 272 LYS F CB  1 
ATOM   3367 C CG  . LYS B 2 237 ? -23.61379 9.87284   44.50557  1.000 129.37029 ? 272 LYS F CG  1 
ATOM   3368 C CD  . LYS B 2 237 ? -24.03132 10.31147  45.90518  1.000 142.62183 ? 272 LYS F CD  1 
ATOM   3369 C CE  . LYS B 2 237 ? -23.49518 9.36894   46.97582  1.000 141.54241 ? 272 LYS F CE  1 
ATOM   3370 N NZ  . LYS B 2 237 ? -23.92034 9.77907   48.34638  1.000 139.04557 ? 272 LYS F NZ  1 
ATOM   3371 N N   . LEU B 2 238 ? -26.66286 11.64995  41.48466  1.000 107.73781 ? 273 LEU F N   1 
ATOM   3372 C CA  . LEU B 2 238 ? -27.16686 12.62250  40.52868  1.000 109.04473 ? 273 LEU F CA  1 
ATOM   3373 C C   . LEU B 2 238 ? -28.50381 13.15981  41.00241  1.000 107.48162 ? 273 LEU F C   1 
ATOM   3374 O O   . LEU B 2 238 ? -28.73806 14.37435  40.99366  1.000 103.94639 ? 273 LEU F O   1 
ATOM   3375 C CB  . LEU B 2 238 ? -27.28498 11.99545  39.14310  1.000 108.91269 ? 273 LEU F CB  1 
ATOM   3376 C CG  . LEU B 2 238 ? -27.68429 12.98794  38.05242  1.000 116.93740 ? 273 LEU F CG  1 
ATOM   3377 C CD1 . LEU B 2 238 ? -26.62453 14.07210  37.90650  1.000 123.18049 ? 273 LEU F CD1 1 
ATOM   3378 C CD2 . LEU B 2 238 ? -27.92369 12.27128  36.73279  1.000 121.55669 ? 273 LEU F CD2 1 
ATOM   3379 N N   . MET B 2 239 ? -29.40450 12.26562  41.40506  1.000 103.11512 ? 274 MET F N   1 
ATOM   3380 C CA  . MET B 2 239 ? -30.69873 12.74067  41.85875  1.000 102.36395 ? 274 MET F CA  1 
ATOM   3381 C C   . MET B 2 239 ? -30.56813 13.48809  43.18007  1.000 103.48097 ? 274 MET F C   1 
ATOM   3382 O O   . MET B 2 239 ? -31.35515 14.40071  43.44796  1.000 103.37215 ? 274 MET F O   1 
ATOM   3383 C CB  . MET B 2 239 ? -31.66167 11.56456  42.00578  1.000 95.10256  ? 274 MET F CB  1 
ATOM   3384 C CG  . MET B 2 239 ? -31.87309 10.78758  40.72798  1.000 100.11261 ? 274 MET F CG  1 
ATOM   3385 S SD  . MET B 2 239 ? -32.98468 9.37522   40.88636  1.000 95.87336  ? 274 MET F SD  1 
ATOM   3386 C CE  . MET B 2 239 ? -34.52929 10.17892  41.29085  1.000 92.99876  ? 274 MET F CE  1 
ATOM   3387 N N   . SER B 2 240 ? -29.58391 13.12385  44.01611  1.000 101.05383 ? 275 SER F N   1 
ATOM   3388 C CA  . SER B 2 240 ? -29.41636 13.79042  45.30409  1.000 103.17733 ? 275 SER F CA  1 
ATOM   3389 C C   . SER B 2 240 ? -28.78607 15.17986  45.21305  1.000 105.72311 ? 275 SER F C   1 
ATOM   3390 O O   . SER B 2 240 ? -29.06819 16.02617  46.06772  1.000 110.66856 ? 275 SER F O   1 
ATOM   3391 C CB  . SER B 2 240 ? -28.58220 12.90905  46.23521  1.000 101.38815 ? 275 SER F CB  1 
ATOM   3392 O OG  . SER B 2 240 ? -29.21429 11.65967  46.45348  1.000 95.72321  ? 275 SER F OG  1 
ATOM   3393 N N   . ASN B 2 241 ? -27.93969 15.45650  44.21720  1.000 102.98776 ? 276 ASN F N   1 
ATOM   3394 C CA  . ASN B 2 241 ? -27.41600 16.81823  44.11632  1.000 110.19382 ? 276 ASN F CA  1 
ATOM   3395 C C   . ASN B 2 241 ? -28.31206 17.74509  43.31302  1.000 113.39419 ? 276 ASN F C   1 
ATOM   3396 O O   . ASN B 2 241 ? -28.08929 18.96181  43.31568  1.000 118.23344 ? 276 ASN F O   1 
ATOM   3397 C CB  . ASN B 2 241 ? -26.00042 16.83035  43.53273  1.000 120.18157 ? 276 ASN F CB  1 
ATOM   3398 C CG  . ASN B 2 241 ? -24.99015 16.18017  44.45512  1.000 125.50424 ? 276 ASN F CG  1 
ATOM   3399 O OD1 . ASN B 2 241 ? -25.35082 15.39678  45.33369  1.000 124.90132 ? 276 ASN F OD1 1 
ATOM   3400 N ND2 . ASN B 2 241 ? -23.71963 16.52706  44.28210  1.000 129.64279 ? 276 ASN F ND2 1 
ATOM   3401 N N   . ASN B 2 242 ? -29.31398 17.19752  42.64176  1.000 108.30303 ? 277 ASN F N   1 
ATOM   3402 C CA  . ASN B 2 242 ? -30.28337 17.93010  41.84116  1.000 107.81644 ? 277 ASN F CA  1 
ATOM   3403 C C   . ASN B 2 242 ? -31.67633 17.46050  42.20308  1.000 96.35777  ? 277 ASN F C   1 
ATOM   3404 O O   . ASN B 2 242 ? -32.46954 17.02925  41.36427  1.000 89.43427  ? 277 ASN F O   1 
ATOM   3405 C CB  . ASN B 2 242 ? -29.97722 17.78581  40.35776  1.000 113.16586 ? 277 ASN F CB  1 
ATOM   3406 C CG  . ASN B 2 242 ? -28.57148 18.22944  40.02396  1.000 125.22802 ? 277 ASN F CG  1 
ATOM   3407 O OD1 . ASN B 2 242 ? -28.12238 19.28020  40.48262  1.000 133.68646 ? 277 ASN F OD1 1 
ATOM   3408 N ND2 . ASN B 2 242 ? -27.86657 17.43531  39.22935  1.000 119.66550 ? 277 ASN F ND2 1 
ATOM   3409 N N   . VAL B 2 243 ? -31.96975 17.53330  43.50142  1.000 94.16203  ? 278 VAL F N   1 
ATOM   3410 C CA  . VAL B 2 243 ? -33.24041 17.05316  44.02179  1.000 89.05821  ? 278 VAL F CA  1 
ATOM   3411 C C   . VAL B 2 243 ? -34.38849 17.90285  43.51397  1.000 84.71543  ? 278 VAL F C   1 
ATOM   3412 O O   . VAL B 2 243 ? -35.49950 17.40008  43.32736  1.000 83.22595  ? 278 VAL F O   1 
ATOM   3413 C CB  . VAL B 2 243 ? -33.20363 17.03964  45.55824  1.000 91.69890  ? 278 VAL F CB  1 
ATOM   3414 C CG1 . VAL B 2 243 ? -32.19892 16.02603  46.04598  1.000 103.29759 ? 278 VAL F CG1 1 
ATOM   3415 C CG2 . VAL B 2 243 ? -32.85355 18.42664  46.07938  1.000 81.03881  ? 278 VAL F CG2 1 
ATOM   3416 N N   . GLN B 2 244 ? -34.15471 19.19317  43.28279  1.000 84.45101  ? 279 GLN F N   1 
ATOM   3417 C CA  . GLN B 2 244 ? -35.22988 20.04786  42.79706  1.000 80.51514  ? 279 GLN F CA  1 
ATOM   3418 C C   . GLN B 2 244 ? -35.62587 19.68062  41.37399  1.000 83.94326  ? 279 GLN F C   1 
ATOM   3419 O O   . GLN B 2 244 ? -36.81881 19.64787  41.03910  1.000 86.49667  ? 279 GLN F O   1 
ATOM   3420 C CB  . GLN B 2 244 ? -34.79313 21.50668  42.88054  1.000 80.18900  ? 279 GLN F CB  1 
ATOM   3421 C CG  . GLN B 2 244 ? -34.60093 21.95765  44.30735  1.000 96.05364  ? 279 GLN F CG  1 
ATOM   3422 C CD  . GLN B 2 244 ? -35.86460 21.79842  45.12595  1.000 107.52200 ? 279 GLN F CD  1 
ATOM   3423 O OE1 . GLN B 2 244 ? -35.84859 21.20244  46.20321  1.000 114.58360 ? 279 GLN F OE1 1 
ATOM   3424 N NE2 . GLN B 2 244 ? -36.96771 22.34207  44.62410  1.000 100.90094 ? 279 GLN F NE2 1 
ATOM   3425 N N   . ILE B 2 245 ? -34.64433 19.33084  40.54386  1.000 90.72034  ? 280 ILE F N   1 
ATOM   3426 C CA  . ILE B 2 245 ? -34.94982 18.86637  39.19724  1.000 92.88552  ? 280 ILE F CA  1 
ATOM   3427 C C   . ILE B 2 245 ? -35.66969 17.52646  39.24572  1.000 86.06704  ? 280 ILE F C   1 
ATOM   3428 O O   . ILE B 2 245 ? -36.56765 17.25791  38.43875  1.000 81.25677  ? 280 ILE F O   1 
ATOM   3429 C CB  . ILE B 2 245 ? -33.65828 18.80102  38.36688  1.000 97.23824  ? 280 ILE F CB  1 
ATOM   3430 C CG1 . ILE B 2 245 ? -33.11392 20.21068  38.16035  1.000 91.51616  ? 280 ILE F CG1 1 
ATOM   3431 C CG2 . ILE B 2 245 ? -33.90899 18.13371  37.03344  1.000 99.50358  ? 280 ILE F CG2 1 
ATOM   3432 C CD1 . ILE B 2 245 ? -31.90414 20.25079  37.30887  1.000 98.26779  ? 280 ILE F CD1 1 
ATOM   3433 N N   . VAL B 2 246 ? -35.29128 16.66567  40.18950  1.000 86.15099  ? 281 VAL F N   1 
ATOM   3434 C CA  . VAL B 2 246 ? -35.98701 15.39425  40.35440  1.000 81.10164  ? 281 VAL F CA  1 
ATOM   3435 C C   . VAL B 2 246 ? -37.44346 15.63364  40.73736  1.000 79.70142  ? 281 VAL F C   1 
ATOM   3436 O O   . VAL B 2 246 ? -38.35383 14.96145  40.23762  1.000 74.95068  ? 281 VAL F O   1 
ATOM   3437 C CB  . VAL B 2 246 ? -35.25396 14.52572  41.39219  1.000 81.28995  ? 281 VAL F CB  1 
ATOM   3438 C CG1 . VAL B 2 246 ? -36.08775 13.31942  41.75315  1.000 83.90228  ? 281 VAL F CG1 1 
ATOM   3439 C CG2 . VAL B 2 246 ? -33.90016 14.10198  40.85523  1.000 77.00031  ? 281 VAL F CG2 1 
ATOM   3440 N N   . ARG B 2 247 ? -37.68234 16.59527  41.63373  1.000 82.49050  ? 282 ARG F N   1 
ATOM   3441 C CA  . ARG B 2 247 ? -39.04386 16.93689  42.03774  1.000 79.50054  ? 282 ARG F CA  1 
ATOM   3442 C C   . ARG B 2 247 ? -39.86651 17.45237  40.86788  1.000 78.43482  ? 282 ARG F C   1 
ATOM   3443 O O   . ARG B 2 247 ? -41.03869 17.08900  40.71532  1.000 78.29570  ? 282 ARG F O   1 
ATOM   3444 C CB  . ARG B 2 247 ? -39.02251 17.97064  43.16444  1.000 85.12752  ? 282 ARG F CB  1 
ATOM   3445 C CG  . ARG B 2 247 ? -38.45549 17.45015  44.46938  1.000 90.87821  ? 282 ARG F CG  1 
ATOM   3446 C CD  . ARG B 2 247 ? -38.51448 18.49917  45.56923  1.000 86.94802  ? 282 ARG F CD  1 
ATOM   3447 N NE  . ARG B 2 247 ? -38.03578 17.97196  46.84057  1.000 94.07248  ? 282 ARG F NE  1 
ATOM   3448 C CZ  . ARG B 2 247 ? -38.79610 17.31026  47.70242  1.000 93.59031  ? 282 ARG F CZ  1 
ATOM   3449 N NH1 . ARG B 2 247 ? -40.07438 17.07687  47.45650  1.000 81.10717  ? 282 ARG F NH1 1 
ATOM   3450 N NH2 . ARG B 2 247 ? -38.26313 16.87931  48.84293  1.000 95.49660  ? 282 ARG F NH2 1 
ATOM   3451 N N   . GLN B 2 248 ? -39.27185 18.29838  40.02916  1.000 82.25163  ? 283 GLN F N   1 
ATOM   3452 C CA  . GLN B 2 248 ? -40.01556 18.84261  38.89921  1.000 87.77648  ? 283 GLN F CA  1 
ATOM   3453 C C   . GLN B 2 248 ? -40.36274 17.78648  37.85737  1.000 88.84801  ? 283 GLN F C   1 
ATOM   3454 O O   . GLN B 2 248 ? -41.26291 18.01902  37.04430  1.000 89.00182  ? 283 GLN F O   1 
ATOM   3455 C CB  . GLN B 2 248 ? -39.25696 19.99279  38.23644  1.000 97.72346  ? 283 GLN F CB  1 
ATOM   3456 C CG  . GLN B 2 248 ? -39.09316 21.22281  39.11155  1.000 107.78044 ? 283 GLN F CG  1 
ATOM   3457 C CD  . GLN B 2 248 ? -37.71060 21.83486  39.01843  1.000 122.09603 ? 283 GLN F CD  1 
ATOM   3458 O OE1 . GLN B 2 248 ? -36.80374 21.26202  38.41730  1.000 123.56112 ? 283 GLN F OE1 1 
ATOM   3459 N NE2 . GLN B 2 248 ? -37.54764 23.01750  39.60256  1.000 125.84346 ? 283 GLN F NE2 1 
ATOM   3460 N N   . GLN B 2 249 ? -39.69088 16.63454  37.86440  1.000 90.13016  ? 284 GLN F N   1 
ATOM   3461 C CA  . GLN B 2 249 ? -39.98731 15.55459  36.92902  1.000 89.72752  ? 284 GLN F CA  1 
ATOM   3462 C C   . GLN B 2 249 ? -40.64392 14.34436  37.59381  1.000 88.44501  ? 284 GLN F C   1 
ATOM   3463 O O   . GLN B 2 249 ? -40.47955 13.21214  37.13099  1.000 87.09623  ? 284 GLN F O   1 
ATOM   3464 C CB  . GLN B 2 249 ? -38.71222 15.12405  36.20766  1.000 90.27493  ? 284 GLN F CB  1 
ATOM   3465 C CG  . GLN B 2 249 ? -38.14381 16.18426  35.27818  1.000 94.18466  ? 284 GLN F CG  1 
ATOM   3466 C CD  . GLN B 2 249 ? -36.95414 15.68446  34.48201  1.000 97.22987  ? 284 GLN F CD  1 
ATOM   3467 O OE1 . GLN B 2 249 ? -36.37819 14.64410  34.79813  1.000 91.25451  ? 284 GLN F OE1 1 
ATOM   3468 N NE2 . GLN B 2 249 ? -36.57646 16.42710  33.44512  1.000 106.46235 ? 284 GLN F NE2 1 
ATOM   3469 N N   . SER B 2 250 ? -41.39647 14.56453  38.67074  1.000 86.32111  ? 285 SER F N   1 
ATOM   3470 C CA  . SER B 2 250 ? -42.08656 13.49135  39.37050  1.000 86.18098  ? 285 SER F CA  1 
ATOM   3471 C C   . SER B 2 250 ? -43.58073 13.79032  39.41167  1.000 84.35442  ? 285 SER F C   1 
ATOM   3472 O O   . SER B 2 250 ? -44.01251 14.91766  39.15503  1.000 84.16635  ? 285 SER F O   1 
ATOM   3473 C CB  . SER B 2 250 ? -41.55476 13.31731  40.79929  1.000 85.01272  ? 285 SER F CB  1 
ATOM   3474 O OG  . SER B 2 250 ? -40.18405 12.97231  40.79806  1.000 84.19616  ? 285 SER F OG  1 
ATOM   3475 N N   . TYR B 2 251 ? -44.37370 12.76470  39.74079  1.000 83.18718  ? 286 TYR F N   1 
ATOM   3476 C CA  . TYR B 2 251 ? -45.81980 12.91082  39.86939  1.000 83.12641  ? 286 TYR F CA  1 
ATOM   3477 C C   . TYR B 2 251 ? -46.28981 12.32696  41.19813  1.000 82.78528  ? 286 TYR F C   1 
ATOM   3478 O O   . TYR B 2 251 ? -45.72014 11.35774  41.69774  1.000 89.74015  ? 286 TYR F O   1 
ATOM   3479 C CB  . TYR B 2 251 ? -46.56033 12.21231  38.69190  1.000 88.48635  ? 286 TYR F CB  1 
ATOM   3480 C CG  . TYR B 2 251 ? -46.49494 12.96881  37.37600  1.000 87.29546  ? 286 TYR F CG  1 
ATOM   3481 C CD1 . TYR B 2 251 ? -45.37118 12.89026  36.56100  1.000 101.84346 ? 286 TYR F CD1 1 
ATOM   3482 C CD2 . TYR B 2 251 ? -47.55866 13.74980  36.94292  1.000 83.10306  ? 286 TYR F CD2 1 
ATOM   3483 C CE1 . TYR B 2 251 ? -45.30189 13.58869  35.36122  1.000 112.46349 ? 286 TYR F CE1 1 
ATOM   3484 C CE2 . TYR B 2 251 ? -47.49862 14.45201  35.73984  1.000 96.30008  ? 286 TYR F CE2 1 
ATOM   3485 C CZ  . TYR B 2 251 ? -46.36862 14.36653  34.95446  1.000 107.99427 ? 286 TYR F CZ  1 
ATOM   3486 O OH  . TYR B 2 251 ? -46.28849 15.05752  33.76301  1.000 95.03184  ? 286 TYR F OH  1 
ATOM   3487 N N   . SER B 2 252 ? -47.31445 12.93613  41.79452  1.000 78.89046  ? 287 SER F N   1 
ATOM   3488 C CA  . SER B 2 252 ? -47.96297 12.39068  42.98734  1.000 79.14910  ? 287 SER F CA  1 
ATOM   3489 C C   . SER B 2 252 ? -49.43531 12.11240  42.70721  1.000 81.01945  ? 287 SER F C   1 
ATOM   3490 O O   . SER B 2 252 ? -50.20091 13.04142  42.41778  1.000 84.32214  ? 287 SER F O   1 
ATOM   3491 C CB  . SER B 2 252 ? -47.79360 13.31514  44.18997  1.000 86.50114  ? 287 SER F CB  1 
ATOM   3492 O OG  . SER B 2 252 ? -46.48634 13.19019  44.72246  1.000 91.50675  ? 287 SER F OG  1 
ATOM   3493 N N   . ILE B 2 253 ? -49.82493 10.84103  42.80806  1.000 77.45196  ? 288 ILE F N   1 
ATOM   3494 C CA  . ILE B 2 253 ? -51.15732 10.36716  42.45309  1.000 80.69321  ? 288 ILE F CA  1 
ATOM   3495 C C   . ILE B 2 253 ? -51.86595 9.83807   43.69109  1.000 88.43033  ? 288 ILE F C   1 
ATOM   3496 O O   . ILE B 2 253 ? -51.30360 9.02033   44.43326  1.000 85.42989  ? 288 ILE F O   1 
ATOM   3497 C CB  . ILE B 2 253 ? -51.12188 9.29226   41.35143  1.000 78.17895  ? 288 ILE F CB  1 
ATOM   3498 C CG1 . ILE B 2 253 ? -50.22665 9.71275   40.19673  1.000 77.63990  ? 288 ILE F CG1 1 
ATOM   3499 C CG2 . ILE B 2 253 ? -52.52099 9.03153   40.84754  1.000 80.90652  ? 288 ILE F CG2 1 
ATOM   3500 C CD1 . ILE B 2 253 ? -48.92073 8.99774   40.14463  1.000 83.94653  ? 288 ILE F CD1 1 
ATOM   3501 N N   . MET B 2 254 ? -53.10223 10.30678  43.90125  1.000 85.16701  ? 289 MET F N   1 
ATOM   3502 C CA  . MET B 2 254 ? -53.90486 9.86543   45.02797  1.000 81.81940  ? 289 MET F CA  1 
ATOM   3503 C C   . MET B 2 254 ? -54.57612 8.54116   44.72811  1.000 90.40715  ? 289 MET F C   1 
ATOM   3504 O O   . MET B 2 254 ? -55.22218 8.36897   43.68549  1.000 98.59481  ? 289 MET F O   1 
ATOM   3505 C CB  . MET B 2 254 ? -54.94611 10.92722  45.33967  1.000 75.54352  ? 289 MET F CB  1 
ATOM   3506 C CG  . MET B 2 254 ? -56.18070 10.48881  46.13917  1.000 72.76268  ? 289 MET F CG  1 
ATOM   3507 S SD  . MET B 2 254 ? -55.97836 9.95160   47.83179  1.000 88.37919  ? 289 MET F SD  1 
ATOM   3508 C CE  . MET B 2 254 ? -57.66713 9.51408   48.27399  1.000 93.76068  ? 289 MET F CE  1 
ATOM   3509 N N   . CYS B 2 255 ? -54.40876 7.60808   45.67230  1.000 91.24097  ? 290 CYS F N   1 
ATOM   3510 C CA  . CYS B 2 255 ? -54.94381 6.25510   45.60264  1.000 91.53234  ? 290 CYS F CA  1 
ATOM   3511 C C   . CYS B 2 255 ? -56.27758 6.19589   46.33819  1.000 99.75724  ? 290 CYS F C   1 
ATOM   3512 O O   . CYS B 2 255 ? -57.28357 6.65977   45.79866  1.000 101.92269 ? 290 CYS F O   1 
ATOM   3513 C CB  . CYS B 2 255 ? -53.94877 5.25241   46.17015  1.000 97.93491  ? 290 CYS F CB  1 
ATOM   3514 S SG  . CYS B 2 255 ? -52.64574 4.70817   45.00024  1.000 124.96636 ? 290 CYS F SG  1 
ATOM   3515 N N   . ILE B 2 256 ? -56.31452 5.65052   47.55869  1.000 97.04533  ? 291 ILE F N   1 
ATOM   3516 C CA  . ILE B 2 256 ? -57.58408 5.41290   48.22953  1.000 97.15483  ? 291 ILE F CA  1 
ATOM   3517 C C   . ILE B 2 256 ? -57.48751 5.74505   49.70874  1.000 86.83487  ? 291 ILE F C   1 
ATOM   3518 O O   . ILE B 2 256 ? -56.40610 5.73567   50.29480  1.000 77.95569  ? 291 ILE F O   1 
ATOM   3519 C CB  . ILE B 2 256 ? -57.97593 3.92140   48.05667  1.000 101.57728 ? 291 ILE F CB  1 
ATOM   3520 C CG1 . ILE B 2 256 ? -59.42585 3.66311   48.43776  1.000 99.69944  ? 291 ILE F CG1 1 
ATOM   3521 C CG2 . ILE B 2 256 ? -57.03368 3.02752   48.86088  1.000 86.49763  ? 291 ILE F CG2 1 
ATOM   3522 C CD1 . ILE B 2 256 ? -59.81949 2.20327   48.37426  1.000 100.08665 ? 291 ILE F CD1 1 
ATOM   3523 N N   . ILE B 2 257 ? -58.62852 6.09948   50.29658  1.000 92.00826  ? 292 ILE F N   1 
ATOM   3524 C CA  . ILE B 2 257 ? -58.78313 6.23160   51.73768  1.000 88.02693  ? 292 ILE F CA  1 
ATOM   3525 C C   . ILE B 2 257 ? -59.69023 5.11053   52.18294  1.000 88.19373  ? 292 ILE F C   1 
ATOM   3526 O O   . ILE B 2 257 ? -60.87502 5.08400   51.84132  1.000 84.70356  ? 292 ILE F O   1 
ATOM   3527 C CB  . ILE B 2 257 ? -59.34748 7.58858   52.14996  1.000 83.65170  ? 292 ILE F CB  1 
ATOM   3528 C CG1 . ILE B 2 257 ? -58.30573 8.66549   51.97363  1.000 76.40990  ? 292 ILE F CG1 1 
ATOM   3529 C CG2 . ILE B 2 257 ? -59.81427 7.56235   53.59226  1.000 92.49987  ? 292 ILE F CG2 1 
ATOM   3530 C CD1 . ILE B 2 257 ? -58.71870 9.95082   52.54559  1.000 83.23139  ? 292 ILE F CD1 1 
ATOM   3531 N N   . LYS B 2 258 ? -59.14907 4.19288   52.97374  1.000 80.77363  ? 293 LYS F N   1 
ATOM   3532 C CA  . LYS B 2 258 ? -59.90395 3.01588   53.37964  1.000 89.07223  ? 293 LYS F CA  1 
ATOM   3533 C C   . LYS B 2 258 ? -59.29913 2.47630   54.66690  1.000 82.05635  ? 293 LYS F C   1 
ATOM   3534 O O   . LYS B 2 258 ? -58.08029 2.30697   54.75313  1.000 75.48199  ? 293 LYS F O   1 
ATOM   3535 C CB  . LYS B 2 258 ? -59.98818 1.96629   52.26941  1.000 92.52966  ? 293 LYS F CB  1 
ATOM   3536 C CG  . LYS B 2 258 ? -61.38054 1.31541   52.25344  1.000 94.64189  ? 293 LYS F CG  1 
ATOM   3537 C CD  . LYS B 2 258 ? -62.45179 2.41580   52.27485  1.000 88.77909  ? 293 LYS F CD  1 
ATOM   3538 C CE  . LYS B 2 258 ? -63.87738 1.89552   52.22053  1.000 77.29669  ? 293 LYS F CE  1 
ATOM   3539 N NZ  . LYS B 2 258 ? -64.83560 3.03676   52.23189  1.000 76.50864  ? 293 LYS F NZ  1 
ATOM   3540 N N   . GLU B 2 259 ? -60.15306 2.21816   55.65966  1.000 76.65468  ? 294 GLU F N   1 
ATOM   3541 C CA  . GLU B 2 259 ? -59.71999 1.60568   56.91454  1.000 74.15868  ? 294 GLU F CA  1 
ATOM   3542 C C   . GLU B 2 259 ? -58.62332 2.42883   57.57850  1.000 74.72444  ? 294 GLU F C   1 
ATOM   3543 O O   . GLU B 2 259 ? -57.53344 1.93010   57.87481  1.000 71.72082  ? 294 GLU F O   1 
ATOM   3544 C CB  . GLU B 2 259 ? -59.18572 0.20230   56.62542  1.000 80.04562  ? 294 GLU F CB  1 
ATOM   3545 C CG  . GLU B 2 259 ? -60.16847 -0.82971  56.12493  1.000 84.23740  ? 294 GLU F CG  1 
ATOM   3546 C CD  . GLU B 2 259 ? -59.79111 -2.24216  56.55422  1.000 89.08210  ? 294 GLU F CD  1 
ATOM   3547 O OE1 . GLU B 2 259 ? -58.72834 -2.40138  57.19900  1.000 85.05460  ? 294 GLU F OE1 1 
ATOM   3548 O OE2 . GLU B 2 259 ? -60.53741 -3.19159  56.22218  1.000 95.32615  ? 294 GLU F OE2 1 
ATOM   3549 N N   . GLU B 2 260 ? -58.91510 3.71103   57.80353  1.000 75.12796  ? 295 GLU F N   1 
ATOM   3550 C CA  . GLU B 2 260 ? -58.02930 4.59092   58.55843  1.000 74.94394  ? 295 GLU F CA  1 
ATOM   3551 C C   . GLU B 2 260 ? -56.66178 4.69482   57.91243  1.000 77.04629  ? 295 GLU F C   1 
ATOM   3552 O O   . GLU B 2 260 ? -55.64344 4.83699   58.60409  1.000 74.08171  ? 295 GLU F O   1 
ATOM   3553 C CB  . GLU B 2 260 ? -57.87815 4.16562   60.02297  1.000 79.50297  ? 295 GLU F CB  1 
ATOM   3554 C CG  . GLU B 2 260 ? -59.14174 3.77253   60.74444  1.000 85.94221  ? 295 GLU F CG  1 
ATOM   3555 C CD  . GLU B 2 260 ? -58.92162 3.52385   62.22714  1.000 84.13369  ? 295 GLU F CD  1 
ATOM   3556 O OE1 . GLU B 2 260 ? -58.72182 4.51616   62.95574  1.000 83.43155  ? 295 GLU F OE1 1 
ATOM   3557 O OE2 . GLU B 2 260 ? -58.90208 2.35138   62.65993  1.000 82.28152  ? 295 GLU F OE2 1 
ATOM   3558 N N   . VAL B 2 261 ? -56.59877 4.62821   56.58442  1.000 83.61496  ? 296 VAL F N   1 
ATOM   3559 C CA  . VAL B 2 261 ? -55.33736 4.70271   55.85601  1.000 75.69180  ? 296 VAL F CA  1 
ATOM   3560 C C   . VAL B 2 261 ? -55.52342 5.58263   54.62974  1.000 68.58859  ? 296 VAL F C   1 
ATOM   3561 O O   . VAL B 2 261 ? -56.44766 5.36849   53.83959  1.000 64.79067  ? 296 VAL F O   1 
ATOM   3562 C CB  . VAL B 2 261 ? -54.82878 3.30718   55.45235  1.000 69.15766  ? 296 VAL F CB  1 
ATOM   3563 C CG1 . VAL B 2 261 ? -53.66247 3.43103   54.50460  1.000 60.53816  ? 296 VAL F CG1 1 
ATOM   3564 C CG2 . VAL B 2 261 ? -54.43216 2.51283   56.68013  1.000 78.48288  ? 296 VAL F CG2 1 
ATOM   3565 N N   . LEU B 2 262 ? -54.64520 6.56928   54.47268  1.000 70.07336  ? 297 LEU F N   1 
ATOM   3566 C CA  . LEU B 2 262 ? -54.55827 7.40636   53.28185  1.000 71.55251  ? 297 LEU F CA  1 
ATOM   3567 C C   . LEU B 2 262 ? -53.29810 7.03094   52.51709  1.000 70.75099  ? 297 LEU F C   1 
ATOM   3568 O O   . LEU B 2 262 ? -52.19347 7.19865   53.03543  1.000 72.63581  ? 297 LEU F O   1 
ATOM   3569 C CB  . LEU B 2 262 ? -54.53193 8.89117   53.63429  1.000 71.01681  ? 297 LEU F CB  1 
ATOM   3570 C CG  . LEU B 2 262 ? -53.99748 9.75743   52.49031  1.000 59.41015  ? 297 LEU F CG  1 
ATOM   3571 C CD1 . LEU B 2 262 ? -54.90152 9.66597   51.27463  1.000 68.39698  ? 297 LEU F CD1 1 
ATOM   3572 C CD2 . LEU B 2 262 ? -53.81268 11.19407  52.92986  1.000 54.31034  ? 297 LEU F CD2 1 
ATOM   3573 N N   . ALA B 2 263 ? -53.44948 6.54383   51.29558  1.000 66.50868  ? 298 ALA F N   1 
ATOM   3574 C CA  . ALA B 2 263 ? -52.30307 6.07844   50.53390  1.000 69.27016  ? 298 ALA F CA  1 
ATOM   3575 C C   . ALA B 2 263 ? -52.23465 6.84061   49.22401  1.000 74.30222  ? 298 ALA F C   1 
ATOM   3576 O O   . ALA B 2 263 ? -53.26387 7.12365   48.60520  1.000 82.15789  ? 298 ALA F O   1 
ATOM   3577 C CB  . ALA B 2 263 ? -52.38902 4.57583   50.25195  1.000 69.27211  ? 298 ALA F CB  1 
ATOM   3578 N N   . TYR B 2 264 ? -51.01581 7.17200   48.80719  1.000 76.60151  ? 299 TYR F N   1 
ATOM   3579 C CA  . TYR B 2 264 ? -50.80450 7.80540   47.51399  1.000 80.34003  ? 299 TYR F CA  1 
ATOM   3580 C C   . TYR B 2 264 ? -49.43146 7.42285   46.97808  1.000 86.73528  ? 299 TYR F C   1 
ATOM   3581 O O   . TYR B 2 264 ? -48.49106 7.21375   47.74245  1.000 85.08602  ? 299 TYR F O   1 
ATOM   3582 C CB  . TYR B 2 264 ? -50.96111 9.33478   47.60129  1.000 73.86339  ? 299 TYR F CB  1 
ATOM   3583 C CG  . TYR B 2 264 ? -50.00263 10.01983  48.55187  1.000 67.17912  ? 299 TYR F CG  1 
ATOM   3584 C CD1 . TYR B 2 264 ? -50.32758 10.18812  49.88736  1.000 67.40495  ? 299 TYR F CD1 1 
ATOM   3585 C CD2 . TYR B 2 264 ? -48.76046 10.46227  48.12268  1.000 68.24361  ? 299 TYR F CD2 1 
ATOM   3586 C CE1 . TYR B 2 264 ? -49.45550 10.80141  50.76063  1.000 68.08594  ? 299 TYR F CE1 1 
ATOM   3587 C CE2 . TYR B 2 264 ? -47.87742 11.06726  48.99520  1.000 64.11853  ? 299 TYR F CE2 1 
ATOM   3588 C CZ  . TYR B 2 264 ? -48.23222 11.23834  50.30884  1.000 64.15429  ? 299 TYR F CZ  1 
ATOM   3589 O OH  . TYR B 2 264 ? -47.36106 11.84893  51.17916  1.000 72.58452  ? 299 TYR F OH  1 
ATOM   3590 N N   . VAL B 2 265 ? -49.32634 7.34253   45.65111  1.000 82.90646  ? 300 VAL F N   1 
ATOM   3591 C CA  . VAL B 2 265 ? -48.13124 6.85289   44.96665  1.000 81.66124  ? 300 VAL F CA  1 
ATOM   3592 C C   . VAL B 2 265 ? -47.30532 8.03367   44.46905  1.000 77.60386  ? 300 VAL F C   1 
ATOM   3593 O O   . VAL B 2 265 ? -47.84559 8.97510   43.86973  1.000 73.83905  ? 300 VAL F O   1 
ATOM   3594 C CB  . VAL B 2 265 ? -48.50685 5.91765   43.80371  1.000 87.04709  ? 300 VAL F CB  1 
ATOM   3595 C CG1 . VAL B 2 265 ? -47.29809 5.63921   42.92230  1.000 94.98944  ? 300 VAL F CG1 1 
ATOM   3596 C CG2 . VAL B 2 265 ? -49.09517 4.62033   44.32950  1.000 101.75236 ? 300 VAL F CG2 1 
ATOM   3597 N N   . VAL B 2 266 ? -45.99637 7.99213   44.72905  1.000 75.19256  ? 301 VAL F N   1 
ATOM   3598 C CA  . VAL B 2 266 ? -45.04305 8.94589   44.16736  1.000 77.60162  ? 301 VAL F CA  1 
ATOM   3599 C C   . VAL B 2 266 ? -44.27133 8.28503   43.02950  1.000 91.98630  ? 301 VAL F C   1 
ATOM   3600 O O   . VAL B 2 266 ? -43.64365 7.23460   43.21403  1.000 89.44213  ? 301 VAL F O   1 
ATOM   3601 C CB  . VAL B 2 266 ? -44.07903 9.46898   45.24335  1.000 76.00644  ? 301 VAL F CB  1 
ATOM   3602 C CG1 . VAL B 2 266 ? -43.00754 10.34827  44.62001  1.000 81.46073  ? 301 VAL F CG1 1 
ATOM   3603 C CG2 . VAL B 2 266 ? -44.84293 10.22371  46.31575  1.000 86.04645  ? 301 VAL F CG2 1 
ATOM   3604 N N   . GLN B 2 267 ? -44.33752 8.90286   41.85192  1.000 97.94128  ? 302 GLN F N   1 
ATOM   3605 C CA  . GLN B 2 267 ? -43.74095 8.40807   40.61791  1.000 82.53863  ? 302 GLN F CA  1 
ATOM   3606 C C   . GLN B 2 267 ? -42.48668 9.23315   40.33164  1.000 85.27499  ? 302 GLN F C   1 
ATOM   3607 O O   . GLN B 2 267 ? -42.58657 10.39848  39.92496  1.000 80.84148  ? 302 GLN F O   1 
ATOM   3608 C CB  . GLN B 2 267 ? -44.76103 8.52536   39.48767  1.000 86.11693  ? 302 GLN F CB  1 
ATOM   3609 C CG  . GLN B 2 267 ? -44.44490 7.77738   38.21569  1.000 109.13574 ? 302 GLN F CG  1 
ATOM   3610 C CD  . GLN B 2 267 ? -45.59765 7.83444   37.21677  1.000 118.33450 ? 302 GLN F CD  1 
ATOM   3611 O OE1 . GLN B 2 267 ? -45.64837 7.05276   36.26662  1.000 126.03578 ? 302 GLN F OE1 1 
ATOM   3612 N NE2 . GLN B 2 267 ? -46.52368 8.76700   37.42661  1.000 111.94568 ? 302 GLN F NE2 1 
ATOM   3613 N N   . LEU B 2 268 ? -41.29225 8.62784   40.54742  1.000 97.02798  ? 303 LEU F N   1 
ATOM   3614 C CA  . LEU B 2 268 ? -40.02773 9.34628   40.42996  1.000 105.59640 ? 303 LEU F CA  1 
ATOM   3615 C C   . LEU B 2 268 ? -39.31799 9.01326   39.11983  1.000 110.36466 ? 303 LEU F C   1 
ATOM   3616 O O   . LEU B 2 268 ? -39.45574 7.90206   38.59834  1.000 111.42624 ? 303 LEU F O   1 
ATOM   3617 C CB  . LEU B 2 268 ? -39.09833 9.01878   41.60381  1.000 102.40378 ? 303 LEU F CB  1 
ATOM   3618 C CG  . LEU B 2 268 ? -39.60109 9.34474   43.01102  1.000 94.46958  ? 303 LEU F CG  1 
ATOM   3619 C CD1 . LEU B 2 268 ? -40.25392 8.12436   43.64416  1.000 101.64803 ? 303 LEU F CD1 1 
ATOM   3620 C CD2 . LEU B 2 268 ? -38.47636 9.88265   43.87852  1.000 99.04398  ? 303 LEU F CD2 1 
ATOM   3621 N N   . PRO B 2 269 ? -38.56125 9.95143   38.54773  1.000 104.84323 ? 304 PRO F N   1 
ATOM   3622 C CA  . PRO B 2 269 ? -37.94734 9.69858   37.24074  1.000 99.91859  ? 304 PRO F CA  1 
ATOM   3623 C C   . PRO B 2 269 ? -36.74519 8.77735   37.39922  1.000 116.83789 ? 304 PRO F C   1 
ATOM   3624 O O   . PRO B 2 269 ? -35.99682 8.86092   38.37856  1.000 119.19961 ? 304 PRO F O   1 
ATOM   3625 C CB  . PRO B 2 269 ? -37.52695 11.09695  36.77502  1.000 96.81556  ? 304 PRO F CB  1 
ATOM   3626 C CG  . PRO B 2 269 ? -37.27495 11.83497  38.03864  1.000 97.03779  ? 304 PRO F CG  1 
ATOM   3627 C CD  . PRO B 2 269 ? -38.29080 11.31894  39.02373  1.000 100.57188 ? 304 PRO F CD  1 
ATOM   3628 N N   . LEU B 2 270 ? -36.56384 7.88669   36.42385  1.000 119.53600 ? 305 LEU F N   1 
ATOM   3629 C CA  . LEU B 2 270 ? -35.37416 7.04631   36.33760  1.000 119.97597 ? 305 LEU F CA  1 
ATOM   3630 C C   . LEU B 2 270 ? -34.56373 7.39692   35.09520  1.000 120.84228 ? 305 LEU F C   1 
ATOM   3631 O O   . LEU B 2 270 ? -35.05886 7.28191   33.96588  1.000 118.36140 ? 305 LEU F O   1 
ATOM   3632 C CB  . LEU B 2 270 ? -35.75787 5.56798   36.33371  1.000 113.65141 ? 305 LEU F CB  1 
ATOM   3633 C CG  . LEU B 2 270 ? -36.20335 5.05345   37.70542  1.000 117.73203 ? 305 LEU F CG  1 
ATOM   3634 C CD1 . LEU B 2 270 ? -36.50754 3.56012   37.67629  1.000 109.56079 ? 305 LEU F CD1 1 
ATOM   3635 C CD2 . LEU B 2 270 ? -35.19005 5.39593   38.79204  1.000 125.70003 ? 305 LEU F CD2 1 
ATOM   3636 N N   . TYR B 2 271 ? -33.31603 7.80437   35.31225  1.000 125.98007 ? 306 TYR F N   1 
ATOM   3637 C CA  . TYR B 2 271 ? -32.41506 8.24106   34.25027  1.000 126.87793 ? 306 TYR F CA  1 
ATOM   3638 C C   . TYR B 2 271 ? -31.55366 7.02788   33.90165  1.000 129.58750 ? 306 TYR F C   1 
ATOM   3639 O O   . TYR B 2 271 ? -30.50161 6.80805   34.50236  1.000 136.25021 ? 306 TYR F O   1 
ATOM   3640 C CB  . TYR B 2 271 ? -31.56401 9.39856   34.75356  1.000 127.44051 ? 306 TYR F CB  1 
ATOM   3641 C CG  . TYR B 2 271 ? -32.36593 10.60203  35.18974  1.000 113.46739 ? 306 TYR F CG  1 
ATOM   3642 C CD1 . TYR B 2 271 ? -32.85117 11.52475  34.27657  1.000 111.35729 ? 306 TYR F CD1 1 
ATOM   3643 C CD2 . TYR B 2 271 ? -32.63197 10.80977  36.53760  1.000 112.48885 ? 306 TYR F CD2 1 
ATOM   3644 C CE1 . TYR B 2 271 ? -33.58272 12.62171  34.69681  1.000 103.20152 ? 306 TYR F CE1 1 
ATOM   3645 C CE2 . TYR B 2 271 ? -33.35682 11.89710  36.96530  1.000 114.33945 ? 306 TYR F CE2 1 
ATOM   3646 C CZ  . TYR B 2 271 ? -33.83136 12.80141  36.04270  1.000 105.27482 ? 306 TYR F CZ  1 
ATOM   3647 O OH  . TYR B 2 271 ? -34.55701 13.89005  36.47023  1.000 109.30666 ? 306 TYR F OH  1 
ATOM   3648 N N   . GLY B 2 272 ? -31.99314 6.22278   32.92964  1.000 120.07170 ? 307 GLY F N   1 
ATOM   3649 C CA  . GLY B 2 272 ? -31.16262 5.09290   32.53422  1.000 119.56506 ? 307 GLY F CA  1 
ATOM   3650 C C   . GLY B 2 272 ? -29.89761 5.46197   31.78555  1.000 122.17574 ? 307 GLY F C   1 
ATOM   3651 O O   . GLY B 2 272 ? -28.94924 4.66964   31.76014  1.000 126.09368 ? 307 GLY F O   1 
ATOM   3652 N N   . VAL B 2 273 ? -29.86106 6.64423   31.18372  1.000 121.51909 ? 308 VAL F N   1 
ATOM   3653 C CA  . VAL B 2 273 ? -28.69930 7.15702   30.46487  1.000 117.89364 ? 308 VAL F CA  1 
ATOM   3654 C C   . VAL B 2 273 ? -28.14169 8.32597   31.27139  1.000 117.69254 ? 308 VAL F C   1 
ATOM   3655 O O   . VAL B 2 273 ? -28.85946 9.28949   31.57117  1.000 108.98104 ? 308 VAL F O   1 
ATOM   3656 C CB  . VAL B 2 273 ? -29.01133 7.51311   29.00037  1.000 107.93762 ? 308 VAL F CB  1 
ATOM   3657 C CG1 . VAL B 2 273 ? -29.73355 6.35326   28.32227  1.000 97.46294  ? 308 VAL F CG1 1 
ATOM   3658 C CG2 . VAL B 2 273 ? -29.79954 8.76549   28.87681  1.000 106.21381 ? 308 VAL F CG2 1 
ATOM   3659 N N   . ILE B 2 274 ? -26.89021 8.20558   31.69484  1.000 118.98396 ? 309 ILE F N   1 
ATOM   3660 C CA  . ILE B 2 274 ? -26.23871 9.20810   32.52597  1.000 122.11434 ? 309 ILE F CA  1 
ATOM   3661 C C   . ILE B 2 274 ? -24.92653 9.59547   31.86970  1.000 123.41064 ? 309 ILE F C   1 
ATOM   3662 O O   . ILE B 2 274 ? -24.22227 8.74280   31.31714  1.000 131.00372 ? 309 ILE F O   1 
ATOM   3663 C CB  . ILE B 2 274 ? -25.97952 8.68351   33.95324  1.000 130.96625 ? 309 ILE F CB  1 
ATOM   3664 C CG1 . ILE B 2 274 ? -27.28521 8.24932   34.60635  1.000 136.48443 ? 309 ILE F CG1 1 
ATOM   3665 C CG2 . ILE B 2 274 ? -25.28616 9.74010   34.81204  1.000 127.74456 ? 309 ILE F CG2 1 
ATOM   3666 C CD1 . ILE B 2 274 ? -27.09670 7.76906   36.00740  1.000 138.51606 ? 309 ILE F CD1 1 
ATOM   3667 N N   . ASP B 2 275 ? -24.61505 10.89537  31.92069  1.000 121.73258 ? 310 ASP F N   1 
ATOM   3668 C CA  . ASP B 2 275 ? -23.38231 11.44826  31.36126  1.000 133.82554 ? 310 ASP F CA  1 
ATOM   3669 C C   . ASP B 2 275 ? -23.29617 11.21280  29.85054  1.000 143.41941 ? 310 ASP F C   1 
ATOM   3670 O O   . ASP B 2 275 ? -22.22967 10.90775  29.31285  1.000 148.32686 ? 310 ASP F O   1 
ATOM   3671 C CB  . ASP B 2 275 ? -22.16447 10.84974  32.07552  1.000 136.18628 ? 310 ASP F CB  1 
ATOM   3672 C CG  . ASP B 2 275 ? -21.93068 11.45708  33.44793  1.000 130.90678 ? 310 ASP F CG  1 
ATOM   3673 O OD1 . ASP B 2 275 ? -22.53762 12.50372  33.75081  1.000 131.69482 ? 310 ASP F OD1 1 
ATOM   3674 O OD2 . ASP B 2 275 ? -21.16305 10.86591  34.23710  1.000 123.10512 ? 310 ASP F OD2 1 
ATOM   3675 N N   . THR B 2 276 ? -24.44080 11.34995  29.15038  1.000 142.98367 ? 311 THR F N   1 
ATOM   3676 C CA  . THR B 2 276 ? -24.39492 11.19327  27.68772  1.000 142.34808 ? 311 THR F CA  1 
ATOM   3677 C C   . THR B 2 276 ? -24.13832 12.52144  26.95359  1.000 148.24917 ? 311 THR F C   1 
ATOM   3678 O O   . THR B 2 276 ? -24.63495 13.56586  27.36420  1.000 142.98870 ? 311 THR F O   1 
ATOM   3679 C CB  . THR B 2 276 ? -25.69926 10.57737  27.17852  1.000 131.21313 ? 311 THR F CB  1 
ATOM   3680 O OG1 . THR B 2 276 ? -25.67579 10.49984  25.74774  1.000 144.77959 ? 311 THR F OG1 1 
ATOM   3681 C CG2 . THR B 2 276 ? -26.90087 11.39913  27.62343  1.000 123.07896 ? 311 THR F CG2 1 
ATOM   3682 N N   . PRO B 2 277 ? -23.39443 12.51522  25.84354  1.000 153.36927 ? 312 PRO F N   1 
ATOM   3683 C CA  . PRO B 2 277 ? -23.15178 13.76201  25.09157  1.000 139.27000 ? 312 PRO F CA  1 
ATOM   3684 C C   . PRO B 2 277 ? -24.43219 14.40438  24.55613  1.000 133.36948 ? 312 PRO F C   1 
ATOM   3685 O O   . PRO B 2 277 ? -25.32217 13.72397  24.04136  1.000 131.68614 ? 312 PRO F O   1 
ATOM   3686 C CB  . PRO B 2 277 ? -22.23007 13.31243  23.95072  1.000 149.09949 ? 312 PRO F CB  1 
ATOM   3687 C CG  . PRO B 2 277 ? -21.57198 12.07065  24.46222  1.000 156.47423 ? 312 PRO F CG  1 
ATOM   3688 C CD  . PRO B 2 277 ? -22.60563 11.38888  25.31201  1.000 158.56902 ? 312 PRO F CD  1 
ATOM   3689 N N   . CYS B 2 278 ? -24.52252 15.73408  24.69243  1.000 129.84038 ? 313 CYS F N   1 
ATOM   3690 C CA  . CYS B 2 278 ? -25.67950 16.49738  24.22816  1.000 131.89954 ? 313 CYS F CA  1 
ATOM   3691 C C   . CYS B 2 278 ? -25.24389 17.77022  23.50731  1.000 127.79780 ? 313 CYS F C   1 
ATOM   3692 O O   . CYS B 2 278 ? -24.16225 18.31117  23.75346  1.000 123.73393 ? 313 CYS F O   1 
ATOM   3693 C CB  . CYS B 2 278 ? -26.62267 16.89698  25.37971  1.000 131.48570 ? 313 CYS F CB  1 
ATOM   3694 S SG  . CYS B 2 278 ? -27.60096 15.56945  26.12902  1.000 147.67307 ? 313 CYS F SG  1 
ATOM   3695 N N   . TRP B 2 279 ? -26.12245 18.24197  22.61422  1.000 129.67506 ? 314 TRP F N   1 
ATOM   3696 C CA  . TRP B 2 279 ? -25.89244 19.37887  21.73038  1.000 127.53656 ? 314 TRP F CA  1 
ATOM   3697 C C   . TRP B 2 279 ? -27.09792 20.31210  21.81017  1.000 116.55294 ? 314 TRP F C   1 
ATOM   3698 O O   . TRP B 2 279 ? -28.23118 19.85444  21.98164  1.000 118.41741 ? 314 TRP F O   1 
ATOM   3699 C CB  . TRP B 2 279 ? -25.70001 18.90983  20.26181  1.000 135.99999 ? 314 TRP F CB  1 
ATOM   3700 C CG  . TRP B 2 279 ? -24.37612 18.22813  19.94071  1.000 147.83247 ? 314 TRP F CG  1 
ATOM   3701 C CD1 . TRP B 2 279 ? -23.64011 17.42867  20.77063  1.000 149.64993 ? 314 TRP F CD1 1 
ATOM   3702 C CD2 . TRP B 2 279 ? -23.69359 18.21430  18.67312  1.000 156.74284 ? 314 TRP F CD2 1 
ATOM   3703 N NE1 . TRP B 2 279 ? -22.51948 16.96777  20.11991  1.000 147.15005 ? 314 TRP F NE1 1 
ATOM   3704 C CE2 . TRP B 2 279 ? -22.53257 17.42915  18.83032  1.000 156.72628 ? 314 TRP F CE2 1 
ATOM   3705 C CE3 . TRP B 2 279 ? -23.94250 18.80248  17.42867  1.000 157.06488 ? 314 TRP F CE3 1 
ATOM   3706 C CZ2 . TRP B 2 279 ? -21.62251 17.22194  17.79151  1.000 159.70832 ? 314 TRP F CZ2 1 
ATOM   3707 C CZ3 . TRP B 2 279 ? -23.03482 18.59856  16.39928  1.000 155.21288 ? 314 TRP F CZ3 1 
ATOM   3708 C CH2 . TRP B 2 279 ? -21.89164 17.81352  16.58717  1.000 158.72593 ? 314 TRP F CH2 1 
ATOM   3709 N N   . LYS B 2 280 ? -26.86542 21.62350  21.67892  1.000 109.02166 ? 315 LYS F N   1 
ATOM   3710 C CA  . LYS B 2 280 ? -27.95760 22.60124  21.66796  1.000 116.11145 ? 315 LYS F CA  1 
ATOM   3711 C C   . LYS B 2 280 ? -27.90828 23.49202  20.43421  1.000 128.03013 ? 315 LYS F C   1 
ATOM   3712 O O   . LYS B 2 280 ? -26.93213 24.22050  20.23066  1.000 133.73066 ? 315 LYS F O   1 
ATOM   3713 C CB  . LYS B 2 280 ? -27.87879 23.47707  22.92573  1.000 120.13440 ? 315 LYS F CB  1 
ATOM   3714 C CG  . LYS B 2 280 ? -29.03638 24.44371  23.17312  1.000 124.19362 ? 315 LYS F CG  1 
ATOM   3715 C CD  . LYS B 2 280 ? -30.41603 23.82456  23.26025  1.000 125.97837 ? 315 LYS F CD  1 
ATOM   3716 C CE  . LYS B 2 280 ? -31.46878 24.93576  23.31603  1.000 120.84099 ? 315 LYS F CE  1 
ATOM   3717 N NZ  . LYS B 2 280 ? -32.87880 24.45431  23.32232  1.000 123.08691 ? 315 LYS F NZ  1 
ATOM   3718 N N   . LEU B 2 281 ? -28.97821 23.45189  19.63294  1.000 129.05286 ? 316 LEU F N   1 
ATOM   3719 C CA  . LEU B 2 281 ? -29.09936 24.24904  18.41489  1.000 126.72985 ? 316 LEU F CA  1 
ATOM   3720 C C   . LEU B 2 281 ? -29.84567 25.56738  18.62964  1.000 128.53346 ? 316 LEU F C   1 
ATOM   3721 O O   . LEU B 2 281 ? -30.94487 25.57378  19.19362  1.000 126.62637 ? 316 LEU F O   1 
ATOM   3722 C CB  . LEU B 2 281 ? -29.78972 23.43846  17.31650  1.000 125.17460 ? 316 LEU F CB  1 
ATOM   3723 C CG  . LEU B 2 281 ? -30.13855 24.22645  16.05121  1.000 130.14745 ? 316 LEU F CG  1 
ATOM   3724 C CD1 . LEU B 2 281 ? -28.87260 24.74001  15.38930  1.000 130.06795 ? 316 LEU F CD1 1 
ATOM   3725 C CD2 . LEU B 2 281 ? -30.93612 23.38143  15.07095  1.000 137.70975 ? 316 LEU F CD2 1 
ATOM   3726 N N   . HIS B 2 282 ? -29.25809 26.67564  18.17875  1.000 131.00413 ? 317 HIS F N   1 
ATOM   3727 C CA  . HIS B 2 282 ? -29.90578 27.98607  18.18913  1.000 127.99140 ? 317 HIS F CA  1 
ATOM   3728 C C   . HIS B 2 282 ? -30.02708 28.44217  16.73890  1.000 128.25314 ? 317 HIS F C   1 
ATOM   3729 O O   . HIS B 2 282 ? -29.05485 28.34663  15.98449  1.000 133.29771 ? 317 HIS F O   1 
ATOM   3730 C CB  . HIS B 2 282 ? -29.15449 29.02588  19.03175  1.000 125.17493 ? 317 HIS F CB  1 
ATOM   3731 C CG  . HIS B 2 282 ? -28.92769 28.61698  20.45489  1.000 121.00886 ? 317 HIS F CG  1 
ATOM   3732 N ND1 . HIS B 2 282 ? -27.81979 27.90830  20.86592  1.000 115.87341 ? 317 HIS F ND1 1 
ATOM   3733 C CD2 . HIS B 2 282 ? -29.67329 28.82600  21.56631  1.000 122.99468 ? 317 HIS F CD2 1 
ATOM   3734 C CE1 . HIS B 2 282 ? -27.89260 27.69800  22.16852  1.000 117.10583 ? 317 HIS F CE1 1 
ATOM   3735 N NE2 . HIS B 2 282 ? -29.00843 28.24363  22.61741  1.000 119.83122 ? 317 HIS F NE2 1 
ATOM   3736 N N   . THR B 2 283 ? -31.20292 28.93311  16.33491  1.000 123.03147 ? 318 THR F N   1 
ATOM   3737 C CA  . THR B 2 283 ? -31.39743 29.33085  14.94327  1.000 133.07820 ? 318 THR F CA  1 
ATOM   3738 C C   . THR B 2 283 ? -31.91307 30.76182  14.84372  1.000 134.82290 ? 318 THR F C   1 
ATOM   3739 O O   . THR B 2 283 ? -32.57449 31.26595  15.75605  1.000 124.20325 ? 318 THR F O   1 
ATOM   3740 C CB  . THR B 2 283 ? -32.37818 28.39268  14.21867  1.000 135.37727 ? 318 THR F CB  1 
ATOM   3741 O OG1 . THR B 2 283 ? -33.68051 28.50840  14.80528  1.000 135.22154 ? 318 THR F OG1 1 
ATOM   3742 C CG2 . THR B 2 283 ? -31.91094 26.94647  14.32213  1.000 130.78577 ? 318 THR F CG2 1 
ATOM   3743 N N   . SER B 2 284 ? -31.60625 31.41208  13.71764  1.000 146.33626 ? 319 SER F N   1 
ATOM   3744 C CA  . SER B 2 284 ? -32.02517 32.78925  13.48533  1.000 147.35038 ? 319 SER F CA  1 
ATOM   3745 C C   . SER B 2 284 ? -32.23856 33.03788  11.99473  1.000 145.50480 ? 319 SER F C   1 
ATOM   3746 O O   . SER B 2 284 ? -31.57225 32.41235  11.16088  1.000 139.82828 ? 319 SER F O   1 
ATOM   3747 C CB  . SER B 2 284 ? -30.98594 33.77117  14.04950  1.000 142.10657 ? 319 SER F CB  1 
ATOM   3748 O OG  . SER B 2 284 ? -31.48492 35.09575  14.08813  1.000 146.60554 ? 319 SER F OG  1 
ATOM   3749 N N   . PRO B 2 285 ? -33.16221 33.93402  11.63349  1.000 142.86935 ? 320 PRO F N   1 
ATOM   3750 C CA  . PRO B 2 285 ? -33.46607 34.18852  10.21327  1.000 151.26644 ? 320 PRO F CA  1 
ATOM   3751 C C   . PRO B 2 285 ? -32.28146 34.73524  9.41414   1.000 163.45545 ? 320 PRO F C   1 
ATOM   3752 O O   . PRO B 2 285 ? -31.53405 35.59237  9.89043   1.000 162.71208 ? 320 PRO F O   1 
ATOM   3753 C CB  . PRO B 2 285 ? -34.61129 35.20514  10.27933  1.000 148.62070 ? 320 PRO F CB  1 
ATOM   3754 C CG  . PRO B 2 285 ? -35.24706 34.97030  11.60302  1.000 135.77285 ? 320 PRO F CG  1 
ATOM   3755 C CD  . PRO B 2 285 ? -34.12697 34.59748  12.52812  1.000 137.67293 ? 320 PRO F CD  1 
ATOM   3756 N N   . LEU B 2 286 ? -32.12408 34.23227  8.17815   1.000 168.13491 ? 321 LEU F N   1 
ATOM   3757 C CA  . LEU B 2 286 ? -31.06644 34.63402  7.23556   1.000 158.53455 ? 321 LEU F CA  1 
ATOM   3758 C C   . LEU B 2 286 ? -31.69196 35.24386  5.97313   1.000 159.27592 ? 321 LEU F C   1 
ATOM   3759 O O   . LEU B 2 286 ? -32.16514 34.51206  5.09730   1.000 157.99538 ? 321 LEU F O   1 
ATOM   3760 C CB  . LEU B 2 286 ? -30.17651 33.44265  6.88372   1.000 142.40167 ? 321 LEU F CB  1 
ATOM   3761 C CG  . LEU B 2 286 ? -28.99966 33.69471  5.93991   1.000 132.33767 ? 321 LEU F CG  1 
ATOM   3762 C CD1 . LEU B 2 286 ? -27.95265 34.55407  6.60567   1.000 132.98359 ? 321 LEU F CD1 1 
ATOM   3763 C CD2 . LEU B 2 286 ? -28.39913 32.36927  5.51609   1.000 136.75605 ? 321 LEU F CD2 1 
ATOM   3764 N N   . CYS B 2 287 ? -31.69683 36.57676  5.87391   1.000 163.40113 ? 322 CYS F N   1 
ATOM   3765 C CA  . CYS B 2 287 ? -32.30734 37.31072  4.76584   1.000 168.16862 ? 322 CYS F CA  1 
ATOM   3766 C C   . CYS B 2 287 ? -31.25295 38.00845  3.90068   1.000 173.38705 ? 322 CYS F C   1 
ATOM   3767 O O   . CYS B 2 287 ? -30.07927 38.11195  4.26435   1.000 180.92821 ? 322 CYS F O   1 
ATOM   3768 C CB  . CYS B 2 287 ? -33.31540 38.34566  5.29279   1.000 169.29393 ? 322 CYS F CB  1 
ATOM   3769 S SG  . CYS B 2 287 ? -34.59838 37.70813  6.42902   1.000 151.41074 ? 322 CYS F SG  1 
ATOM   3770 N N   . THR B 2 288 ? -31.68429 38.48146  2.72840   1.000 169.00741 ? 323 THR F N   1 
ATOM   3771 C CA  . THR B 2 288 ? -30.86070 39.30497  1.84397   1.000 173.01508 ? 323 THR F CA  1 
ATOM   3772 C C   . THR B 2 288 ? -30.96602 40.77470  2.26579   1.000 173.41346 ? 323 THR F C   1 
ATOM   3773 O O   . THR B 2 288 ? -31.89084 41.16492  2.97785   1.000 166.96716 ? 323 THR F O   1 
ATOM   3774 C CB  . THR B 2 288 ? -31.28048 39.12447  0.38330   1.000 171.35277 ? 323 THR F CB  1 
ATOM   3775 O OG1 . THR B 2 288 ? -31.58982 37.74853  0.13630   1.000 167.59700 ? 323 THR F OG1 1 
ATOM   3776 C CG2 . THR B 2 288 ? -30.16279 39.56244  -0.56923  1.000 164.88425 ? 323 THR F CG2 1 
ATOM   3777 N N   . THR B 2 289 ? -30.01856 41.60369  1.82017   1.000 177.23347 ? 324 THR F N   1 
ATOM   3778 C CA  . THR B 2 289 ? -30.01826 42.94971  2.38205   1.000 172.61315 ? 324 THR F CA  1 
ATOM   3779 C C   . THR B 2 289 ? -30.32779 44.07033  1.39765   1.000 172.32332 ? 324 THR F C   1 
ATOM   3780 O O   . THR B 2 289 ? -29.63834 45.09378  1.37917   1.000 167.73206 ? 324 THR F O   1 
ATOM   3781 C CB  . THR B 2 289 ? -28.63997 43.23090  2.96648   1.000 177.34199 ? 324 THR F CB  1 
ATOM   3782 O OG1 . THR B 2 289 ? -27.65761 43.10616  1.93558   1.000 184.06324 ? 324 THR F OG1 1 
ATOM   3783 C CG2 . THR B 2 289 ? -28.31225 42.19680  4.00925   1.000 182.75174 ? 324 THR F CG2 1 
ATOM   3784 N N   . ASN B 2 290 ? -31.35877 43.88883  0.57842   1.000 176.71810 ? 325 ASN F N   1 
ATOM   3785 C CA  . ASN B 2 290 ? -31.91475 44.92010  -0.29445  1.000 172.71238 ? 325 ASN F CA  1 
ATOM   3786 C C   . ASN B 2 290 ? -32.75961 45.91659  0.50633   1.000 164.96830 ? 325 ASN F C   1 
ATOM   3787 O O   . ASN B 2 290 ? -33.22214 45.64213  1.61754   1.000 160.52047 ? 325 ASN F O   1 
ATOM   3788 C CB  . ASN B 2 290 ? -32.70928 44.32559  -1.46325  1.000 168.15789 ? 325 ASN F CB  1 
ATOM   3789 C CG  . ASN B 2 290 ? -31.80890 43.64504  -2.49948  1.000 156.88117 ? 325 ASN F CG  1 
ATOM   3790 O OD1 . ASN B 2 290 ? -30.58678 43.75925  -2.45001  1.000 151.38252 ? 325 ASN F OD1 1 
ATOM   3791 N ND2 . ASN B 2 290 ? -32.42031 42.89621  -3.41896  1.000 153.62025 ? 325 ASN F ND2 1 
ATOM   3792 N N   . THR B 2 291 ? -32.94866 47.08766  -0.08915  1.000 162.71570 ? 326 THR F N   1 
ATOM   3793 C CA  . THR B 2 291 ? -33.59261 48.26325  0.48407   1.000 156.59317 ? 326 THR F CA  1 
ATOM   3794 C C   . THR B 2 291 ? -35.09796 48.22567  0.23156   1.000 156.97988 ? 326 THR F C   1 
ATOM   3795 O O   . THR B 2 291 ? -35.83192 49.09675  0.71133   1.000 146.50275 ? 326 THR F O   1 
ATOM   3796 C CB  . THR B 2 291 ? -32.98874 49.56397  -0.07221  1.000 147.11332 ? 326 THR F CB  1 
ATOM   3797 O OG1 . THR B 2 291 ? -32.64663 49.40274  -1.45364  1.000 153.56281 ? 326 THR F OG1 1 
ATOM   3798 C CG2 . THR B 2 291 ? -31.74498 49.96698  0.72328   1.000 131.44387 ? 326 THR F CG2 1 
ATOM   3799 N N   . LYS B 2 292 ? -35.54396 47.21450  -0.51087  1.000 162.93419 ? 327 LYS F N   1 
ATOM   3800 C CA  . LYS B 2 292 ? -36.91718 46.95442  -0.92926  1.000 160.05087 ? 327 LYS F CA  1 
ATOM   3801 C C   . LYS B 2 292 ? -37.38016 45.68902  -0.21721  1.000 168.58841 ? 327 LYS F C   1 
ATOM   3802 O O   . LYS B 2 292 ? -36.79615 44.61672  -0.41035  1.000 173.11975 ? 327 LYS F O   1 
ATOM   3803 C CB  . LYS B 2 292 ? -37.00394 46.75027  -2.44197  1.000 160.95083 ? 327 LYS F CB  1 
ATOM   3804 C CG  . LYS B 2 292 ? -38.40127 46.40536  -2.92270  1.000 161.54251 ? 327 LYS F CG  1 
ATOM   3805 C CD  . LYS B 2 292 ? -38.36067 45.82037  -4.31987  1.000 163.78217 ? 327 LYS F CD  1 
ATOM   3806 C CE  . LYS B 2 292 ? -39.75290 45.53087  -4.85286  1.000 159.79406 ? 327 LYS F CE  1 
ATOM   3807 N NZ  . LYS B 2 292 ? -39.72934 45.18133  -6.30272  1.000 137.05800 ? 327 LYS F NZ  1 
ATOM   3808 N N   . GLU B 2 293 ? -38.42173 45.82085  0.61702   1.000 172.44769 ? 328 GLU F N   1 
ATOM   3809 C CA  . GLU B 2 293 ? -38.96545 44.70180  1.38356   1.000 170.99633 ? 328 GLU F CA  1 
ATOM   3810 C C   . GLU B 2 293 ? -39.60953 43.64115  0.50751   1.000 176.36797 ? 328 GLU F C   1 
ATOM   3811 O O   . GLU B 2 293 ? -40.08372 42.63127  1.04068   1.000 170.30439 ? 328 GLU F O   1 
ATOM   3812 C CB  . GLU B 2 293 ? -40.03940 45.19460  2.36144   1.000 155.40491 ? 328 GLU F CB  1 
ATOM   3813 C CG  . GLU B 2 293 ? -39.57713 46.10882  3.48756   1.000 146.82391 ? 328 GLU F CG  1 
ATOM   3814 C CD  . GLU B 2 293 ? -39.49569 47.55943  3.03412   1.000 140.77066 ? 328 GLU F CD  1 
ATOM   3815 O OE1 . GLU B 2 293 ? -40.35519 47.96624  2.22778   1.000 147.72361 ? 328 GLU F OE1 1 
ATOM   3816 O OE2 . GLU B 2 293 ? -38.58585 48.29316  3.47094   1.000 128.35478 ? 328 GLU F OE2 1 
ATOM   3817 N N   . GLY B 2 294 ? -39.62775 43.84161  -0.80573  1.000 179.99806 ? 329 GLY F N   1 
ATOM   3818 C CA  . GLY B 2 294 ? -40.39673 43.03902  -1.73150  1.000 169.33814 ? 329 GLY F CA  1 
ATOM   3819 C C   . GLY B 2 294 ? -39.41366 42.28012  -2.59686  1.000 170.55089 ? 329 GLY F C   1 
ATOM   3820 O O   . GLY B 2 294 ? -39.79798 41.39891  -3.37288  1.000 166.56746 ? 329 GLY F O   1 
ATOM   3821 N N   . SER B 2 295 ? -38.12171 42.60356  -2.42624  1.000 180.16114 ? 330 SER F N   1 
ATOM   3822 C CA  . SER B 2 295 ? -37.02556 41.93713  -3.12416  1.000 184.37933 ? 330 SER F CA  1 
ATOM   3823 C C   . SER B 2 295 ? -36.11565 41.16907  -2.16950  1.000 193.04278 ? 330 SER F C   1 
ATOM   3824 O O   . SER B 2 295 ? -34.99413 40.81143  -2.54605  1.000 189.12549 ? 330 SER F O   1 
ATOM   3825 C CB  . SER B 2 295 ? -36.18851 42.93635  -3.93120  1.000 174.89585 ? 330 SER F CB  1 
ATOM   3826 O OG  . SER B 2 295 ? -35.55572 43.89888  -3.09985  1.000 170.10666 ? 330 SER F OG  1 
ATOM   3827 N N   . ASN B 2 296 ? -36.56474 40.90695  -0.93920  1.000 197.28051 ? 331 ASN F N   1 
ATOM   3828 C CA  . ASN B 2 296 ? -35.74640 40.21378  0.04473   1.000 186.47435 ? 331 ASN F CA  1 
ATOM   3829 C C   . ASN B 2 296 ? -36.43970 38.90117  0.35340   1.000 177.79356 ? 331 ASN F C   1 
ATOM   3830 O O   . ASN B 2 296 ? -37.66928 38.83395  0.39546   1.000 171.25701 ? 331 ASN F O   1 
ATOM   3831 C CB  . ASN B 2 296 ? -35.59943 41.01637  1.36305   1.000 173.64277 ? 331 ASN F CB  1 
ATOM   3832 C CG  . ASN B 2 296 ? -34.52447 42.08566  1.29970   1.000 170.32608 ? 331 ASN F CG  1 
ATOM   3833 O OD1 . ASN B 2 296 ? -33.78090 42.17122  0.32936   1.000 179.97698 ? 331 ASN F OD1 1 
ATOM   3834 N ND2 . ASN B 2 296 ? -34.45484 42.92288  2.33382   1.000 158.15394 ? 331 ASN F ND2 1 
ATOM   3835 N N   . ILE B 2 297 ? -35.65633 37.86487  0.58077   1.000 174.78338 ? 332 ILE F N   1 
ATOM   3836 C CA  . ILE B 2 297 ? -36.21809 36.57072  0.91777   1.000 174.08966 ? 332 ILE F CA  1 
ATOM   3837 C C   . ILE B 2 297 ? -35.61131 36.13213  2.23272   1.000 178.18621 ? 332 ILE F C   1 
ATOM   3838 O O   . ILE B 2 297 ? -34.46355 36.46986  2.54326   1.000 176.71227 ? 332 ILE F O   1 
ATOM   3839 C CB  . ILE B 2 297 ? -35.95646 35.52372  -0.18328  1.000 173.86209 ? 332 ILE F CB  1 
ATOM   3840 C CG1 . ILE B 2 297 ? -34.45204 35.41655  -0.44940  1.000 176.56848 ? 332 ILE F CG1 1 
ATOM   3841 C CG2 . ILE B 2 297 ? -36.71096 35.90382  -1.44350  1.000 180.74641 ? 332 ILE F CG2 1 
ATOM   3842 C CD1 . ILE B 2 297 ? -34.07119 34.41912  -1.51678  1.000 178.74292 ? 332 ILE F CD1 1 
ATOM   3843 N N   . CYS B 2 298 ? -36.37252 35.38127  3.01367   1.000 176.96921 ? 333 CYS F N   1 
ATOM   3844 C CA  . CYS B 2 298 ? -35.85402 34.99522  4.30677   1.000 164.83713 ? 333 CYS F CA  1 
ATOM   3845 C C   . CYS B 2 298 ? -35.93010 33.48649  4.44027   1.000 161.70014 ? 333 CYS F C   1 
ATOM   3846 O O   . CYS B 2 298 ? -36.82515 32.82849  3.89360   1.000 160.67857 ? 333 CYS F O   1 
ATOM   3847 C CB  . CYS B 2 298 ? -36.58540 35.71080  5.44280   1.000 160.83574 ? 333 CYS F CB  1 
ATOM   3848 S SG  . CYS B 2 298 ? -36.32501 37.49497  5.36937   1.000 159.45166 ? 333 CYS F SG  1 
ATOM   3849 N N   . LEU B 2 299 ? -35.11716 33.00723  5.37122   1.000 162.18751 ? 334 LEU F N   1 
ATOM   3850 C CA  . LEU B 2 299 ? -34.90360 31.59525  5.62284   1.000 167.38992 ? 334 LEU F CA  1 
ATOM   3851 C C   . LEU B 2 299 ? -34.41303 31.44273  7.05159   1.000 167.31309 ? 334 LEU F C   1 
ATOM   3852 O O   . LEU B 2 299 ? -33.57508 32.22369  7.50810   1.000 169.57044 ? 334 LEU F O   1 
ATOM   3853 C CB  . LEU B 2 299 ? -33.89981 31.00418  4.61822   1.000 154.67417 ? 334 LEU F CB  1 
ATOM   3854 C CG  . LEU B 2 299 ? -33.43255 29.54987  4.73065   1.000 144.91998 ? 334 LEU F CG  1 
ATOM   3855 C CD1 . LEU B 2 299 ? -33.06620 29.04488  3.35439   1.000 151.06938 ? 334 LEU F CD1 1 
ATOM   3856 C CD2 . LEU B 2 299 ? -32.23303 29.40547  5.65393   1.000 136.33446 ? 334 LEU F CD2 1 
ATOM   3857 N N   . THR B 2 300 ? -34.93053 30.43970  7.74731   1.000 161.86506 ? 335 THR F N   1 
ATOM   3858 C CA  . THR B 2 300 ? -34.56486 30.19157  9.13047   1.000 145.83096 ? 335 THR F CA  1 
ATOM   3859 C C   . THR B 2 300 ? -34.51476 28.68400  9.26240   1.000 139.82152 ? 335 THR F C   1 
ATOM   3860 O O   . THR B 2 300 ? -35.44224 27.98047  8.85257   1.000 143.51862 ? 335 THR F O   1 
ATOM   3861 C CB  . THR B 2 300 ? -35.57182 30.79243  10.12276  1.000 147.39756 ? 335 THR F CB  1 
ATOM   3862 O OG1 . THR B 2 300 ? -35.89017 32.13470  9.73493   1.000 149.46239 ? 335 THR F OG1 1 
ATOM   3863 C CG2 . THR B 2 300 ? -34.99271 30.80240  11.53745  1.000 142.63688 ? 335 THR F CG2 1 
ATOM   3864 N N   . ARG B 2 301 ? -33.43452 28.19854  9.85349   1.000 128.34300 ? 336 ARG F N   1 
ATOM   3865 C CA  . ARG B 2 301 ? -33.34692 26.78640  10.16016  1.000 137.47816 ? 336 ARG F CA  1 
ATOM   3866 C C   . ARG B 2 301 ? -34.40493 26.42608  11.18820  1.000 150.55101 ? 336 ARG F C   1 
ATOM   3867 O O   . ARG B 2 301 ? -34.70131 27.20259  12.09995  1.000 151.59126 ? 336 ARG F O   1 
ATOM   3868 C CB  . ARG B 2 301 ? -31.94274 26.50158  10.68061  1.000 122.84397 ? 336 ARG F CB  1 
ATOM   3869 C CG  . ARG B 2 301 ? -31.47588 25.08172  10.71551  1.000 122.80725 ? 336 ARG F CG  1 
ATOM   3870 C CD  . ARG B 2 301 ? -30.10105 25.13219  11.34509  1.000 128.43957 ? 336 ARG F CD  1 
ATOM   3871 N NE  . ARG B 2 301 ? -29.60760 23.83429  11.77330  1.000 138.37851 ? 336 ARG F NE  1 
ATOM   3872 C CZ  . ARG B 2 301 ? -28.71419 23.11799  11.10938  1.000 136.16623 ? 336 ARG F CZ  1 
ATOM   3873 N NH1 . ARG B 2 301 ? -28.19043 23.54699  9.97205   1.000 136.21967 ? 336 ARG F NH1 1 
ATOM   3874 N NH2 . ARG B 2 301 ? -28.32841 21.94851  11.60673  1.000 144.67109 ? 336 ARG F NH2 1 
ATOM   3875 N N   . THR B 2 302 ? -34.98638 25.24742  11.02983  1.000 152.18155 ? 337 THR F N   1 
ATOM   3876 C CA  . THR B 2 302 ? -36.02109 24.78787  11.93468  1.000 143.12257 ? 337 THR F CA  1 
ATOM   3877 C C   . THR B 2 302 ? -35.47083 23.68360  12.81317  1.000 146.19110 ? 337 THR F C   1 
ATOM   3878 O O   . THR B 2 302 ? -34.31105 23.27548  12.69570  1.000 139.70727 ? 337 THR F O   1 
ATOM   3879 C CB  . THR B 2 302 ? -37.25874 24.30774  11.17651  1.000 149.29055 ? 337 THR F CB  1 
ATOM   3880 O OG1 . THR B 2 302 ? -36.88553 23.29754  10.23175  1.000 160.23371 ? 337 THR F OG1 1 
ATOM   3881 C CG2 . THR B 2 302 ? -37.92261 25.45575  10.46951  1.000 153.75409 ? 337 THR F CG2 1 
ATOM   3882 N N   . ASP B 2 303 ? -36.33742 23.20532  13.69845  1.000 152.20622 ? 338 ASP F N   1 
ATOM   3883 C CA  . ASP B 2 303 ? -36.01881 22.14506  14.64016  1.000 154.12471 ? 338 ASP F CA  1 
ATOM   3884 C C   . ASP B 2 303 ? -34.84201 22.59249  15.50667  1.000 150.49405 ? 338 ASP F C   1 
ATOM   3885 O O   . ASP B 2 303 ? -33.80197 21.93733  15.59419  1.000 152.77150 ? 338 ASP F O   1 
ATOM   3886 C CB  . ASP B 2 303 ? -35.71574 20.83410  13.90261  1.000 155.49583 ? 338 ASP F CB  1 
ATOM   3887 C CG  . ASP B 2 303 ? -36.89996 20.33072  13.09182  1.000 164.03612 ? 338 ASP F CG  1 
ATOM   3888 O OD1 . ASP B 2 303 ? -38.05596 20.59475  13.48794  1.000 167.76787 ? 338 ASP F OD1 1 
ATOM   3889 O OD2 . ASP B 2 303 ? -36.67299 19.68904  12.04349  1.000 162.66366 ? 338 ASP F OD2 1 
ATOM   3890 N N   . ARG B 2 304 ? -35.03482 23.73498  16.15556  1.000 141.33478 ? 339 ARG F N   1 
ATOM   3891 C CA  . ARG B 2 304 ? -34.07570 24.23891  17.12058  1.000 133.07487 ? 339 ARG F CA  1 
ATOM   3892 C C   . ARG B 2 304 ? -34.39520 23.66042  18.49130  1.000 136.48969 ? 339 ARG F C   1 
ATOM   3893 O O   . ARG B 2 304 ? -35.55853 23.41958  18.82416  1.000 141.40668 ? 339 ARG F O   1 
ATOM   3894 C CB  . ARG B 2 304 ? -34.10805 25.77261  17.15404  1.000 128.40828 ? 339 ARG F CB  1 
ATOM   3895 C CG  . ARG B 2 304 ? -35.44543 26.35691  17.62246  1.000 123.42691 ? 339 ARG F CG  1 
ATOM   3896 C CD  . ARG B 2 304 ? -35.37299 27.83550  18.01250  1.000 123.02836 ? 339 ARG F CD  1 
ATOM   3897 N NE  . ARG B 2 304 ? -35.26274 28.73204  16.86782  1.000 132.37940 ? 339 ARG F NE  1 
ATOM   3898 C CZ  . ARG B 2 304 ? -35.16572 30.05243  16.95920  1.000 132.75056 ? 339 ARG F CZ  1 
ATOM   3899 N NH1 . ARG B 2 304 ? -35.16288 30.66677  18.13152  1.000 125.76431 ? 339 ARG F NH1 1 
ATOM   3900 N NH2 . ARG B 2 304 ? -35.06992 30.77526  15.84632  1.000 128.28600 ? 339 ARG F NH2 1 
ATOM   3901 N N   . GLY B 2 305 ? -33.36491 23.43933  19.28337  1.000 136.62142 ? 340 GLY F N   1 
ATOM   3902 C CA  . GLY B 2 305 ? -33.59800 22.88311  20.60194  1.000 133.96746 ? 340 GLY F CA  1 
ATOM   3903 C C   . GLY B 2 305 ? -32.43135 22.01976  21.05348  1.000 124.09746 ? 340 GLY F C   1 
ATOM   3904 O O   . GLY B 2 305 ? -31.29677 22.21095  20.61815  1.000 120.74887 ? 340 GLY F O   1 
ATOM   3905 N N   . TRP B 2 306 ? -32.75781 21.06733  21.92518  1.000 118.18152 ? 341 TRP F N   1 
ATOM   3906 C CA  . TRP B 2 306 ? -31.78152 20.17488  22.53243  1.000 118.03885 ? 341 TRP F CA  1 
ATOM   3907 C C   . TRP B 2 306 ? -31.71840 18.87115  21.74606  1.000 112.81982 ? 341 TRP F C   1 
ATOM   3908 O O   . TRP B 2 306 ? -32.75397 18.27598  21.43162  1.000 115.00667 ? 341 TRP F O   1 
ATOM   3909 C CB  . TRP B 2 306 ? -32.15230 19.91465  23.99415  1.000 129.24276 ? 341 TRP F CB  1 
ATOM   3910 C CG  . TRP B 2 306 ? -31.73199 21.02361  24.93208  1.000 127.03488 ? 341 TRP F CG  1 
ATOM   3911 C CD1 . TRP B 2 306 ? -32.53268 21.99017  25.47621  1.000 120.82438 ? 341 TRP F CD1 1 
ATOM   3912 C CD2 . TRP B 2 306 ? -30.42173 21.24047  25.47412  1.000 128.85095 ? 341 TRP F CD2 1 
ATOM   3913 N NE1 . TRP B 2 306 ? -31.79357 22.81411  26.29346  1.000 120.18652 ? 341 TRP F NE1 1 
ATOM   3914 C CE2 . TRP B 2 306 ? -30.49664 22.37147  26.31400  1.000 123.26584 ? 341 TRP F CE2 1 
ATOM   3915 C CE3 . TRP B 2 306 ? -29.19000 20.59639  25.31989  1.000 129.69109 ? 341 TRP F CE3 1 
ATOM   3916 C CZ2 . TRP B 2 306 ? -29.38563 22.87095  26.99476  1.000 119.07280 ? 341 TRP F CZ2 1 
ATOM   3917 C CZ3 . TRP B 2 306 ? -28.09056 21.09238  25.99873  1.000 120.21348 ? 341 TRP F CZ3 1 
ATOM   3918 C CH2 . TRP B 2 306 ? -28.19559 22.21747  26.82516  1.000 112.79315 ? 341 TRP F CH2 1 
ATOM   3919 N N   . TYR B 2 307 ? -30.50196 18.43697  21.43537  1.000 117.63914 ? 342 TYR F N   1 
ATOM   3920 C CA  . TYR B 2 307 ? -30.22116 17.14789  20.81697  1.000 128.59884 ? 342 TYR F CA  1 
ATOM   3921 C C   . TYR B 2 307 ? -29.29565 16.34467  21.71791  1.000 130.94436 ? 342 TYR F C   1 
ATOM   3922 O O   . TYR B 2 307 ? -28.28666 16.87220  22.19649  1.000 134.00535 ? 342 TYR F O   1 
ATOM   3923 C CB  . TYR B 2 307 ? -29.60268 17.31252  19.42383  1.000 135.63249 ? 342 TYR F CB  1 
ATOM   3924 C CG  . TYR B 2 307 ? -30.50621 17.98510  18.41062  1.000 137.08991 ? 342 TYR F CG  1 
ATOM   3925 C CD1 . TYR B 2 307 ? -30.70600 19.35984  18.42595  1.000 139.02124 ? 342 TYR F CD1 1 
ATOM   3926 C CD2 . TYR B 2 307 ? -31.15202 17.24002  17.42835  1.000 137.00019 ? 342 TYR F CD2 1 
ATOM   3927 C CE1 . TYR B 2 307 ? -31.52934 19.97344  17.49679  1.000 142.93074 ? 342 TYR F CE1 1 
ATOM   3928 C CE2 . TYR B 2 307 ? -31.97456 17.84263  16.49434  1.000 143.25180 ? 342 TYR F CE2 1 
ATOM   3929 C CZ  . TYR B 2 307 ? -32.15859 19.20920  16.53172  1.000 150.61171 ? 342 TYR F CZ  1 
ATOM   3930 O OH  . TYR B 2 307 ? -32.98009 19.81050  15.60519  1.000 155.45372 ? 342 TYR F OH  1 
ATOM   3931 N N   . CYS B 2 308 ? -29.62852 15.07601  21.94889  1.000 131.89520 ? 343 CYS F N   1 
ATOM   3932 C CA  . CYS B 2 308 ? -28.78156 14.22876  22.77924  1.000 140.61001 ? 343 CYS F CA  1 
ATOM   3933 C C   . CYS B 2 308 ? -28.58256 12.84626  22.17836  1.000 139.20939 ? 343 CYS F C   1 
ATOM   3934 O O   . CYS B 2 308 ? -29.50584 12.23551  21.63047  1.000 134.52598 ? 343 CYS F O   1 
ATOM   3935 C CB  . CYS B 2 308 ? -29.30913 14.08064  24.21369  1.000 143.67214 ? 343 CYS F CB  1 
ATOM   3936 S SG  . CYS B 2 308 ? -29.38356 15.61294  25.14070  1.000 150.76913 ? 343 CYS F SG  1 
ATOM   3937 N N   . ASP B 2 309 ? -27.34189 12.37990  22.31635  1.000 139.72829 ? 344 ASP F N   1 
ATOM   3938 C CA  . ASP B 2 309 ? -26.92692 11.03845  21.93895  1.000 144.38151 ? 344 ASP F CA  1 
ATOM   3939 C C   . ASP B 2 309 ? -27.58612 9.96886   22.80093  1.000 143.38707 ? 344 ASP F C   1 
ATOM   3940 O O   . ASP B 2 309 ? -27.60962 10.05679  24.03285  1.000 145.86349 ? 344 ASP F O   1 
ATOM   3941 C CB  . ASP B 2 309 ? -25.40638 10.90526  22.04551  1.000 144.08880 ? 344 ASP F CB  1 
ATOM   3942 C CG  . ASP B 2 309 ? -24.67236 11.65302  20.95168  1.000 148.57459 ? 344 ASP F CG  1 
ATOM   3943 O OD1 . ASP B 2 309 ? -25.33856 12.37231  20.17909  1.000 154.43875 ? 344 ASP F OD1 1 
ATOM   3944 O OD2 . ASP B 2 309 ? -23.43195 11.50875  20.86129  1.000 143.25987 ? 344 ASP F OD2 1 
ATOM   3945 N N   . ASN B 2 310 ? -28.12076 8.95116   22.14159  1.000 144.55831 ? 345 ASN F N   1 
ATOM   3946 C CA  . ASN B 2 310 ? -28.85549 7.88154   22.80650  1.000 146.19341 ? 345 ASN F CA  1 
ATOM   3947 C C   . ASN B 2 310 ? -28.66677 6.65032   21.93284  1.000 157.19891 ? 345 ASN F C   1 
ATOM   3948 O O   . ASN B 2 310 ? -29.30769 6.53573   20.88596  1.000 169.29557 ? 345 ASN F O   1 
ATOM   3949 C CB  . ASN B 2 310 ? -30.33026 8.24678   22.93724  1.000 144.95545 ? 345 ASN F CB  1 
ATOM   3950 C CG  . ASN B 2 310 ? -31.14089 7.17190   23.63731  1.000 158.32965 ? 345 ASN F CG  1 
ATOM   3951 O OD1 . ASN B 2 310 ? -30.59081 6.34613   24.36202  1.000 167.29621 ? 345 ASN F OD1 1 
ATOM   3952 N ND2 . ASN B 2 310 ? -32.45719 7.15533   23.39353  1.000 149.32506 ? 345 ASN F ND2 1 
ATOM   3953 N N   . ALA B 2 311 ? -27.79574 5.73688   22.36951  1.000 152.86227 ? 346 ALA F N   1 
ATOM   3954 C CA  . ALA B 2 311 ? -27.65540 4.42426   21.74920  1.000 158.44495 ? 346 ALA F CA  1 
ATOM   3955 C C   . ALA B 2 311 ? -27.36764 4.58111   20.25978  1.000 159.31961 ? 346 ALA F C   1 
ATOM   3956 O O   . ALA B 2 311 ? -28.02922 3.97683   19.41314  1.000 164.02416 ? 346 ALA F O   1 
ATOM   3957 C CB  . ALA B 2 311 ? -28.89397 3.55502   21.98573  1.000 157.88563 ? 346 ALA F CB  1 
ATOM   3958 N N   . GLY B 2 312 ? -26.37186 5.39099   19.92344  1.000 153.32130 ? 347 GLY F N   1 
ATOM   3959 C CA  . GLY B 2 312 ? -26.09150 5.50745   18.51370  1.000 144.82826 ? 347 GLY F CA  1 
ATOM   3960 C C   . GLY B 2 312 ? -27.03893 6.39451   17.71925  1.000 149.30458 ? 347 GLY F C   1 
ATOM   3961 O O   . GLY B 2 312 ? -26.78120 6.61421   16.53010  1.000 157.25060 ? 347 GLY F O   1 
ATOM   3962 N N   . SER B 2 313 ? -28.12099 6.92099   18.31119  1.000 143.78356 ? 348 SER F N   1 
ATOM   3963 C CA  . SER B 2 313 ? -29.00650 7.82127   17.55664  1.000 141.11918 ? 348 SER F CA  1 
ATOM   3964 C C   . SER B 2 313 ? -29.12723 9.17943   18.25703  1.000 142.48309 ? 348 SER F C   1 
ATOM   3965 O O   . SER B 2 313 ? -28.46553 9.43615   19.26298  1.000 140.32992 ? 348 SER F O   1 
ATOM   3966 C CB  . SER B 2 313 ? -30.39829 7.18758   17.37826  1.000 137.91852 ? 348 SER F CB  1 
ATOM   3967 O OG  . SER B 2 313 ? -31.18727 7.89616   16.43466  1.000 143.32680 ? 348 SER F OG  1 
ATOM   3968 N N   . VAL B 2 314 ? -29.97856 10.05713  17.71406  1.000 146.56819 ? 349 VAL F N   1 
ATOM   3969 C CA  . VAL B 2 314 ? -30.24043 11.36938  18.30308  1.000 145.72449 ? 349 VAL F CA  1 
ATOM   3970 C C   . VAL B 2 314 ? -31.68775 11.52365  18.74660  1.000 149.42353 ? 349 VAL F C   1 
ATOM   3971 O O   . VAL B 2 314 ? -32.60908 11.31205  17.95069  1.000 145.06592 ? 349 VAL F O   1 
ATOM   3972 C CB  . VAL B 2 314 ? -29.86933 12.49572  17.32358  1.000 141.83648 ? 349 VAL F CB  1 
ATOM   3973 C CG1 . VAL B 2 314 ? -30.32959 13.85197  17.87038  1.000 141.09593 ? 349 VAL F CG1 1 
ATOM   3974 C CG2 . VAL B 2 314 ? -28.37156 12.47009  17.02796  1.000 142.93643 ? 349 VAL F CG2 1 
ATOM   3975 N N   . SER B 2 315 ? -31.87837 11.89699  20.01419  1.000 148.94087 ? 350 SER F N   1 
ATOM   3976 C CA  . SER B 2 315 ? -33.18531 12.22161  20.57872  1.000 139.45452 ? 350 SER F CA  1 
ATOM   3977 C C   . SER B 2 315 ? -33.38818 13.73532  20.49776  1.000 129.16446 ? 350 SER F C   1 
ATOM   3978 O O   . SER B 2 315 ? -32.63094 14.49150  21.11930  1.000 115.85193 ? 350 SER F O   1 
ATOM   3979 C CB  . SER B 2 315 ? -33.29597 11.73542  22.02152  1.000 134.80747 ? 350 SER F CB  1 
ATOM   3980 O OG  . SER B 2 315 ? -33.43831 10.32588  22.06519  1.000 121.36270 ? 350 SER F OG  1 
ATOM   3981 N N   . PHE B 2 316 ? -34.37969 14.18262  19.72862  1.000 130.24409 ? 351 PHE F N   1 
ATOM   3982 C CA  . PHE B 2 316 ? -34.68189 15.60706  19.60040  1.000 132.71064 ? 351 PHE F CA  1 
ATOM   3983 C C   . PHE B 2 316 ? -35.86770 15.95656  20.49377  1.000 137.15015 ? 351 PHE F C   1 
ATOM   3984 O O   . PHE B 2 316 ? -36.87116 15.23488  20.50984  1.000 139.64034 ? 351 PHE F O   1 
ATOM   3985 C CB  . PHE B 2 316 ? -34.97862 15.96068  18.13792  1.000 136.73583 ? 351 PHE F CB  1 
ATOM   3986 C CG  . PHE B 2 316 ? -35.50410 17.35693  17.93252  1.000 139.65965 ? 351 PHE F CG  1 
ATOM   3987 C CD1 . PHE B 2 316 ? -34.76545 18.45828  18.32848  1.000 137.59151 ? 351 PHE F CD1 1 
ATOM   3988 C CD2 . PHE B 2 316 ? -36.72126 17.56516  17.30006  1.000 142.66975 ? 351 PHE F CD2 1 
ATOM   3989 C CE1 . PHE B 2 316 ? -35.24298 19.73976  18.12411  1.000 139.55389 ? 351 PHE F CE1 1 
ATOM   3990 C CE2 . PHE B 2 316 ? -37.20553 18.84422  17.08982  1.000 144.54847 ? 351 PHE F CE2 1 
ATOM   3991 C CZ  . PHE B 2 316 ? -36.46460 19.93354  17.50279  1.000 144.40837 ? 351 PHE F CZ  1 
ATOM   3992 N N   . PHE B 2 317 ? -35.75649 17.06469  21.22537  1.000 134.56032 ? 352 PHE F N   1 
ATOM   3993 C CA  . PHE B 2 317 ? -36.80526 17.50152  22.14976  1.000 129.20892 ? 352 PHE F CA  1 
ATOM   3994 C C   . PHE B 2 317 ? -37.35821 18.84283  21.69177  1.000 129.83524 ? 352 PHE F C   1 
ATOM   3995 O O   . PHE B 2 317 ? -36.73534 19.89160  21.93771  1.000 125.88074 ? 352 PHE F O   1 
ATOM   3996 C CB  . PHE B 2 317 ? -36.27822 17.60708  23.58267  1.000 123.93114 ? 352 PHE F CB  1 
ATOM   3997 C CG  . PHE B 2 317 ? -35.57980 16.36436  24.07832  1.000 126.67526 ? 352 PHE F CG  1 
ATOM   3998 C CD1 . PHE B 2 317 ? -36.29528 15.35458  24.70213  1.000 123.83446 ? 352 PHE F CD1 1 
ATOM   3999 C CD2 . PHE B 2 317 ? -34.20495 16.22270  23.95534  1.000 130.52144 ? 352 PHE F CD2 1 
ATOM   4000 C CE1 . PHE B 2 317 ? -35.65827 14.21540  25.17050  1.000 118.73985 ? 352 PHE F CE1 1 
ATOM   4001 C CE2 . PHE B 2 317 ? -33.56134 15.08508  24.42440  1.000 127.40602 ? 352 PHE F CE2 1 
ATOM   4002 C CZ  . PHE B 2 317 ? -34.29006 14.08152  25.03254  1.000 115.88027 ? 352 PHE F CZ  1 
ATOM   4003 N N   . PRO B 2 318 ? -38.51579 18.86842  21.02639  1.000 133.69858 ? 353 PRO F N   1 
ATOM   4004 C CA  . PRO B 2 318 ? -39.02697 20.15573  20.52985  1.000 137.62782 ? 353 PRO F CA  1 
ATOM   4005 C C   . PRO B 2 318 ? -39.60012 21.03510  21.62624  1.000 141.16898 ? 353 PRO F C   1 
ATOM   4006 O O   . PRO B 2 318 ? -39.39211 22.25456  21.60752  1.000 146.46443 ? 353 PRO F O   1 
ATOM   4007 C CB  . PRO B 2 318 ? -40.09585 19.73273  19.51147  1.000 139.11273 ? 353 PRO F CB  1 
ATOM   4008 C CG  . PRO B 2 318 ? -40.54164 18.38358  19.97655  1.000 136.27168 ? 353 PRO F CG  1 
ATOM   4009 C CD  . PRO B 2 318 ? -39.32992 17.72700  20.57487  1.000 130.93359 ? 353 PRO F CD  1 
ATOM   4010 N N   . GLN B 2 319 ? -40.30984 20.45186  22.58686  1.000 142.21023 ? 354 GLN F N   1 
ATOM   4011 C CA  . GLN B 2 319 ? -40.88282 21.22987  23.67726  1.000 142.37290 ? 354 GLN F CA  1 
ATOM   4012 C C   . GLN B 2 319 ? -39.80018 21.72863  24.63157  1.000 141.74957 ? 354 GLN F C   1 
ATOM   4013 O O   . GLN B 2 319 ? -38.81982 21.03327  24.91232  1.000 143.38868 ? 354 GLN F O   1 
ATOM   4014 C CB  . GLN B 2 319 ? -41.94429 20.41100  24.41369  1.000 142.94430 ? 354 GLN F CB  1 
ATOM   4015 C CG  . GLN B 2 319 ? -42.83287 19.59669  23.46937  1.000 142.15666 ? 354 GLN F CG  1 
ATOM   4016 C CD  . GLN B 2 319 ? -43.90193 18.80023  24.19570  1.000 143.39427 ? 354 GLN F CD  1 
ATOM   4017 O OE1 . GLN B 2 319 ? -44.30439 19.14827  25.30480  1.000 148.46299 ? 354 GLN F OE1 1 
ATOM   4018 N NE2 . GLN B 2 319 ? -44.38258 17.73595  23.56121  1.000 136.30344 ? 354 GLN F NE2 1 
ATOM   4019 N N   . ALA B 2 320 ? -39.99798 22.94776  25.14064  1.000 133.87453 ? 355 ALA F N   1 
ATOM   4020 C CA  . ALA B 2 320 ? -38.98736 23.62951  25.94251  1.000 130.60515 ? 355 ALA F CA  1 
ATOM   4021 C C   . ALA B 2 320 ? -38.94078 23.11829  27.37579  1.000 137.32855 ? 355 ALA F C   1 
ATOM   4022 O O   . ALA B 2 320 ? -37.87276 23.13338  27.99894  1.000 130.10512 ? 355 ALA F O   1 
ATOM   4023 C CB  . ALA B 2 320 ? -39.24132 25.13749  25.93300  1.000 123.30934 ? 355 ALA F CB  1 
ATOM   4024 N N   . GLU B 2 321 ? -40.06326 22.65089  27.91121  1.000 139.41413 ? 356 GLU F N   1 
ATOM   4025 C CA  . GLU B 2 321 ? -40.10899 22.22204  29.29944  1.000 132.98205 ? 356 GLU F CA  1 
ATOM   4026 C C   . GLU B 2 321 ? -39.70310 20.77081  29.47373  1.000 129.64798 ? 356 GLU F C   1 
ATOM   4027 O O   . GLU B 2 321 ? -39.68931 20.27978  30.60738  1.000 132.54011 ? 356 GLU F O   1 
ATOM   4028 C CB  . GLU B 2 321 ? -41.52772 22.36596  29.85121  1.000 138.88537 ? 356 GLU F CB  1 
ATOM   4029 C CG  . GLU B 2 321 ? -42.46426 21.31481  29.24877  1.000 144.59860 ? 356 GLU F CG  1 
ATOM   4030 C CD  . GLU B 2 321 ? -43.71241 21.06957  30.07015  1.000 158.20031 ? 356 GLU F CD  1 
ATOM   4031 O OE1 . GLU B 2 321 ? -43.84181 21.67097  31.15765  1.000 169.68538 ? 356 GLU F OE1 1 
ATOM   4032 O OE2 . GLU B 2 321 ? -44.55426 20.25431  29.63292  1.000 154.15643 ? 356 GLU F OE2 1 
ATOM   4033 N N   . THR B 2 322 ? -39.37147 20.07000  28.39254  1.000 126.33442 ? 357 THR F N   1 
ATOM   4034 C CA  . THR B 2 322 ? -38.97284 18.68220  28.55266  1.000 119.13702 ? 357 THR F CA  1 
ATOM   4035 C C   . THR B 2 322 ? -37.50170 18.52791  28.90529  1.000 110.64391 ? 357 THR F C   1 
ATOM   4036 O O   . THR B 2 322 ? -37.05306 17.39529  29.10854  1.000 99.92339  ? 357 THR F O   1 
ATOM   4037 C CB  . THR B 2 322 ? -39.29787 17.89904  27.28225  1.000 118.91269 ? 357 THR F CB  1 
ATOM   4038 O OG1 . THR B 2 322 ? -38.66288 18.52414  26.16201  1.000 122.08302 ? 357 THR F OG1 1 
ATOM   4039 C CG2 . THR B 2 322 ? -40.79287 17.90805  27.05502  1.000 125.15192 ? 357 THR F CG2 1 
ATOM   4040 N N   . CYS B 2 323 ? -36.74075 19.62164  28.99313  1.000 110.41760 ? 358 CYS F N   1 
ATOM   4041 C CA  . CYS B 2 323 ? -35.33714 19.53408  29.38579  1.000 115.66185 ? 358 CYS F CA  1 
ATOM   4042 C C   . CYS B 2 323 ? -35.02224 20.64496  30.37440  1.000 120.55798 ? 358 CYS F C   1 
ATOM   4043 O O   . CYS B 2 323 ? -35.09073 21.82884  30.02673  1.000 121.57584 ? 358 CYS F O   1 
ATOM   4044 C CB  . CYS B 2 323 ? -34.40010 19.65108  28.18097  1.000 116.57615 ? 358 CYS F CB  1 
ATOM   4045 S SG  . CYS B 2 323 ? -34.33136 18.25952  27.05441  1.000 125.46778 ? 358 CYS F SG  1 
ATOM   4046 N N   . LYS B 2 324 ? -34.69843 20.26539  31.60351  1.000 112.81968 ? 359 LYS F N   1 
ATOM   4047 C CA  . LYS B 2 324 ? -34.25123 21.19020  32.63310  1.000 115.12841 ? 359 LYS F CA  1 
ATOM   4048 C C   . LYS B 2 324 ? -32.72908 21.11444  32.67385  1.000 112.21838 ? 359 LYS F C   1 
ATOM   4049 O O   . LYS B 2 324 ? -32.16626 20.01970  32.66144  1.000 105.88876 ? 359 LYS F O   1 
ATOM   4050 C CB  . LYS B 2 324 ? -34.87778 20.87855  33.98876  1.000 127.37356 ? 359 LYS F CB  1 
ATOM   4051 C CG  . LYS B 2 324 ? -36.22771 21.57859  34.14692  1.000 129.62983 ? 359 LYS F CG  1 
ATOM   4052 C CD  . LYS B 2 324 ? -36.10129 23.08729  33.92459  1.000 133.06498 ? 359 LYS F CD  1 
ATOM   4053 C CE  . LYS B 2 324 ? -37.28796 23.86142  34.49068  1.000 137.94670 ? 359 LYS F CE  1 
ATOM   4054 N NZ  . LYS B 2 324 ? -37.46074 23.65645  35.95692  1.000 140.22471 ? 359 LYS F NZ  1 
ATOM   4055 N N   . VAL B 2 325 ? -32.04449 22.24633  32.75217  1.000 111.79729 ? 360 VAL F N   1 
ATOM   4056 C CA  . VAL B 2 325 ? -30.58788 22.22235  32.70745  1.000 113.52863 ? 360 VAL F CA  1 
ATOM   4057 C C   . VAL B 2 325 ? -30.04409 22.67744  34.05071  1.000 122.25074 ? 360 VAL F C   1 
ATOM   4058 O O   . VAL B 2 325 ? -30.50668 23.68241  34.60610  1.000 115.44578 ? 360 VAL F O   1 
ATOM   4059 C CB  . VAL B 2 325 ? -30.05354 23.11725  31.57907  1.000 114.53650 ? 360 VAL F CB  1 
ATOM   4060 C CG1 . VAL B 2 325 ? -28.54663 23.01413  31.49474  1.000 121.79124 ? 360 VAL F CG1 1 
ATOM   4061 C CG2 . VAL B 2 325 ? -30.70870 22.75031  30.25725  1.000 119.63969 ? 360 VAL F CG2 1 
ATOM   4062 N N   . GLN B 2 326 ? -29.06079 21.94092  34.57673  1.000 131.75288 ? 361 GLN F N   1 
ATOM   4063 C CA  . GLN B 2 326 ? -28.33591 22.38557  35.76222  1.000 139.94545 ? 361 GLN F CA  1 
ATOM   4064 C C   . GLN B 2 326 ? -26.84489 22.31817  35.46008  1.000 139.71987 ? 361 GLN F C   1 
ATOM   4065 O O   . GLN B 2 326 ? -26.27442 21.22906  35.38540  1.000 138.40954 ? 361 GLN F O   1 
ATOM   4066 C CB  . GLN B 2 326 ? -28.69839 21.55701  37.00432  1.000 144.63811 ? 361 GLN F CB  1 
ATOM   4067 C CG  . GLN B 2 326 ? -27.76200 21.71693  38.21207  1.000 143.25734 ? 361 GLN F CG  1 
ATOM   4068 C CD  . GLN B 2 326 ? -26.67501 20.65555  38.30587  1.000 145.56326 ? 361 GLN F CD  1 
ATOM   4069 O OE1 . GLN B 2 326 ? -26.74313 19.60903  37.66160  1.000 145.53766 ? 361 GLN F OE1 1 
ATOM   4070 N NE2 . GLN B 2 326 ? -25.66706 20.92337  39.12631  1.000 141.68266 ? 361 GLN F NE2 1 
ATOM   4071 N N   . SER B 2 327 ? -26.20905 23.48652  35.39735  1.000 138.98283 ? 362 SER F N   1 
ATOM   4072 C CA  . SER B 2 327 ? -24.79872 23.70248  35.09289  1.000 137.00985 ? 362 SER F CA  1 
ATOM   4073 C C   . SER B 2 327 ? -24.35669 22.95629  33.84110  1.000 132.42911 ? 362 SER F C   1 
ATOM   4074 O O   . SER B 2 327 ? -24.95632 23.11028  32.77271  1.000 116.67205 ? 362 SER F O   1 
ATOM   4075 C CB  . SER B 2 327 ? -23.91950 23.30158  36.28006  1.000 137.61385 ? 362 SER F CB  1 
ATOM   4076 O OG  . SER B 2 327 ? -22.70665 24.03699  36.28035  1.000 133.40338 ? 362 SER F OG  1 
ATOM   4077 N N   . ASN B 2 328 ? -23.29895 22.16143  33.96516  1.000 139.44402 ? 363 ASN F N   1 
ATOM   4078 C CA  . ASN B 2 328 ? -22.86043 21.30083  32.87576  1.000 144.02098 ? 363 ASN F CA  1 
ATOM   4079 C C   . ASN B 2 328 ? -23.90729 20.24626  32.53304  1.000 145.51912 ? 363 ASN F C   1 
ATOM   4080 O O   . ASN B 2 328 ? -23.97882 19.79455  31.38830  1.000 143.13254 ? 363 ASN F O   1 
ATOM   4081 C CB  . ASN B 2 328 ? -21.53232 20.64722  33.27933  1.000 148.61039 ? 363 ASN F CB  1 
ATOM   4082 C CG  . ASN B 2 328 ? -21.11566 19.52042  32.34067  1.000 148.93632 ? 363 ASN F CG  1 
ATOM   4083 O OD1 . ASN B 2 328 ? -21.19671 18.34036  32.67018  1.000 147.33202 ? 363 ASN F OD1 1 
ATOM   4084 N ND2 . ASN B 2 328 ? -20.66236 19.89628  31.15682  1.000 147.39447 ? 363 ASN F ND2 1 
ATOM   4085 N N   . ARG B 2 329 ? -24.74323 19.87921  33.50416  1.000 146.73375 ? 364 ARG F N   1 
ATOM   4086 C CA  . ARG B 2 329 ? -25.68670 18.77312  33.43053  1.000 139.82843 ? 364 ARG F CA  1 
ATOM   4087 C C   . ARG B 2 329 ? -27.00021 19.19218  32.75757  1.000 123.08026 ? 364 ARG F C   1 
ATOM   4088 O O   . ARG B 2 329 ? -27.40054 20.36032  32.79134  1.000 116.48416 ? 364 ARG F O   1 
ATOM   4089 C CB  . ARG B 2 329 ? -25.99595 18.27867  34.85269  1.000 136.43445 ? 364 ARG F CB  1 
ATOM   4090 C CG  . ARG B 2 329 ? -24.80187 17.69601  35.61520  1.000 136.92502 ? 364 ARG F CG  1 
ATOM   4091 C CD  . ARG B 2 329 ? -24.00835 16.67291  34.82206  1.000 132.70717 ? 364 ARG F CD  1 
ATOM   4092 N NE  . ARG B 2 329 ? -24.83242 15.54558  34.40316  1.000 129.61209 ? 364 ARG F NE  1 
ATOM   4093 C CZ  . ARG B 2 329 ? -24.76883 14.33775  34.94672  1.000 129.84069 ? 364 ARG F CZ  1 
ATOM   4094 N NH1 . ARG B 2 329 ? -23.94208 14.07305  35.94429  1.000 129.28729 ? 364 ARG F NH1 1 
ATOM   4095 N NH2 . ARG B 2 329 ? -25.55641 13.37289  34.47998  1.000 130.25349 ? 364 ARG F NH2 1 
ATOM   4096 N N   . VAL B 2 330 ? -27.69056 18.21790  32.16253  1.000 116.44978 ? 365 VAL F N   1 
ATOM   4097 C CA  . VAL B 2 330 ? -29.01156 18.41209  31.56297  1.000 104.25381 ? 365 VAL F CA  1 
ATOM   4098 C C   . VAL B 2 330 ? -29.87363 17.21302  31.92300  1.000 105.92389 ? 365 VAL F C   1 
ATOM   4099 O O   . VAL B 2 330 ? -29.38630 16.08314  31.93762  1.000 110.83799 ? 365 VAL F O   1 
ATOM   4100 C CB  . VAL B 2 330 ? -28.95880 18.59694  30.03158  1.000 108.45610 ? 365 VAL F CB  1 
ATOM   4101 C CG1 . VAL B 2 330 ? -30.28265 19.16598  29.54632  1.000 109.32703 ? 365 VAL F CG1 1 
ATOM   4102 C CG2 . VAL B 2 330 ? -27.81206 19.50666  29.61855  1.000 117.81036 ? 365 VAL F CG2 1 
ATOM   4103 N N   . PHE B 2 331 ? -31.13689 17.46161  32.26522  1.000 102.65100 ? 366 PHE F N   1 
ATOM   4104 C CA  . PHE B 2 331 ? -32.11216 16.43641  32.62701  1.000 104.88602 ? 366 PHE F CA  1 
ATOM   4105 C C   . PHE B 2 331 ? -33.30613 16.53155  31.67685  1.000 95.44152  ? 366 PHE F C   1 
ATOM   4106 O O   . PHE B 2 331 ? -34.11073 17.46078  31.79183  1.000 93.22607  ? 366 PHE F O   1 
ATOM   4107 C CB  . PHE B 2 331 ? -32.57811 16.62663  34.07111  1.000 107.71635 ? 366 PHE F CB  1 
ATOM   4108 C CG  . PHE B 2 331 ? -31.51852 16.35540  35.11491  1.000 106.31659 ? 366 PHE F CG  1 
ATOM   4109 C CD1 . PHE B 2 331 ? -30.58654 17.32888  35.44870  1.000 110.20205 ? 366 PHE F CD1 1 
ATOM   4110 C CD2 . PHE B 2 331 ? -31.47255 15.14428  35.78179  1.000 104.04514 ? 366 PHE F CD2 1 
ATOM   4111 C CE1 . PHE B 2 331 ? -29.62360 17.09193  36.42012  1.000 113.13113 ? 366 PHE F CE1 1 
ATOM   4112 C CE2 . PHE B 2 331 ? -30.51244 14.90130  36.74962  1.000 111.73485 ? 366 PHE F CE2 1 
ATOM   4113 C CZ  . PHE B 2 331 ? -29.58794 15.87538  37.06893  1.000 115.79032 ? 366 PHE F CZ  1 
ATOM   4114 N N   . CYS B 2 332 ? -33.42564 15.59787  30.73301  1.000 92.99401  ? 367 CYS F N   1 
ATOM   4115 C CA  . CYS B 2 332 ? -34.50965 15.63982  29.74841  1.000 103.69870 ? 367 CYS F CA  1 
ATOM   4116 C C   . CYS B 2 332 ? -35.50350 14.49520  29.90113  1.000 95.73201  ? 367 CYS F C   1 
ATOM   4117 O O   . CYS B 2 332 ? -35.21310 13.47831  30.52965  1.000 92.99569  ? 367 CYS F O   1 
ATOM   4118 C CB  . CYS B 2 332 ? -33.97849 15.63299  28.31375  1.000 119.64416 ? 367 CYS F CB  1 
ATOM   4119 S SG  . CYS B 2 332 ? -32.95631 17.02574  27.90176  1.000 140.37801 ? 367 CYS F SG  1 
ATOM   4120 N N   . ASP B 2 333 ? -36.69956 14.68150  29.32456  1.000 95.39288  ? 368 ASP F N   1 
ATOM   4121 C CA  . ASP B 2 333 ? -37.73005 13.64607  29.32795  1.000 102.80180 ? 368 ASP F CA  1 
ATOM   4122 C C   . ASP B 2 333 ? -38.06257 13.18434  27.91537  1.000 106.73787 ? 368 ASP F C   1 
ATOM   4123 O O   . ASP B 2 333 ? -38.48414 13.98469  27.07369  1.000 112.07061 ? 368 ASP F O   1 
ATOM   4124 C CB  . ASP B 2 333 ? -39.00389 14.19135  29.98057  1.000 108.86880 ? 368 ASP F CB  1 
ATOM   4125 C CG  . ASP B 2 333 ? -39.98457 13.10427  30.35503  1.000 114.33219 ? 368 ASP F CG  1 
ATOM   4126 O OD1 . ASP B 2 333 ? -39.61129 11.91530  30.29609  1.000 118.36984 ? 368 ASP F OD1 1 
ATOM   4127 O OD2 . ASP B 2 333 ? -41.14306 13.44235  30.68188  1.000 109.47479 ? 368 ASP F OD2 1 
ATOM   4128 N N   . THR B 2 334 ? -37.86083 11.88648  27.67200  1.000 103.47819 ? 369 THR F N   1 
ATOM   4129 C CA  . THR B 2 334 ? -38.09226 11.17399  26.41734  1.000 110.05649 ? 369 THR F CA  1 
ATOM   4130 C C   . THR B 2 334 ? -39.55308 10.87142  26.07206  1.000 115.64934 ? 369 THR F C   1 
ATOM   4131 O O   . THR B 2 334 ? -39.80042 10.37816  24.96538  1.000 125.18771 ? 369 THR F O   1 
ATOM   4132 C CB  . THR B 2 334 ? -37.31327 9.85638   26.42987  1.000 108.31305 ? 369 THR F CB  1 
ATOM   4133 O OG1 . THR B 2 334 ? -37.80566 9.01832   27.48220  1.000 104.15009 ? 369 THR F OG1 1 
ATOM   4134 C CG2 . THR B 2 334 ? -35.83289 10.12307  26.65594  1.000 108.28969 ? 369 THR F CG2 1 
ATOM   4135 N N   . MET B 2 335 ? -40.52273 11.12723  26.95986  1.000 115.97810 ? 370 MET F N   1 
ATOM   4136 C CA  . MET B 2 335 ? -41.91519 10.81014  26.62511  1.000 126.34000 ? 370 MET F CA  1 
ATOM   4137 C C   . MET B 2 335 ? -42.44381 11.55346  25.39943  1.000 138.56019 ? 370 MET F C   1 
ATOM   4138 O O   . MET B 2 335 ? -43.17220 10.97176  24.58433  1.000 147.32808 ? 370 MET F O   1 
ATOM   4139 C CB  . MET B 2 335 ? -42.80658 11.07869  27.83863  1.000 119.30488 ? 370 MET F CB  1 
ATOM   4140 C CG  . MET B 2 335 ? -44.28116 10.89045  27.56219  1.000 111.36673 ? 370 MET F CG  1 
ATOM   4141 S SD  . MET B 2 335 ? -45.31485 11.72099  28.77635  1.000 111.36473 ? 370 MET F SD  1 
ATOM   4142 C CE  . MET B 2 335 ? -44.62485 13.37330  28.73733  1.000 121.61537 ? 370 MET F CE  1 
ATOM   4143 N N   . ASN B 2 336 ? -42.09289 12.81943  25.23456  1.000 138.66863 ? 371 ASN F N   1 
ATOM   4144 C CA  . ASN B 2 336 ? -42.56081 13.60811  24.09349  1.000 133.62445 ? 371 ASN F CA  1 
ATOM   4145 C C   . ASN B 2 336 ? -41.34735 14.03557  23.27987  1.000 135.91630 ? 371 ASN F C   1 
ATOM   4146 O O   . ASN B 2 336 ? -41.01434 15.21859  23.19857  1.000 137.73708 ? 371 ASN F O   1 
ATOM   4147 C CB  . ASN B 2 336 ? -43.41858 14.78506  24.53592  1.000 137.49211 ? 371 ASN F CB  1 
ATOM   4148 C CG  . ASN B 2 336 ? -42.90131 15.43958  25.79001  1.000 155.84335 ? 371 ASN F CG  1 
ATOM   4149 O OD1 . ASN B 2 336 ? -41.83468 15.08349  26.29402  1.000 155.80172 ? 371 ASN F OD1 1 
ATOM   4150 N ND2 . ASN B 2 336 ? -43.64751 16.41025  26.30040  1.000 162.85315 ? 371 ASN F ND2 1 
ATOM   4151 N N   . SER B 2 337 ? -40.68285 13.06285  22.67221  1.000 136.52643 ? 372 SER F N   1 
ATOM   4152 C CA  . SER B 2 337 ? -39.47683 13.32536  21.90835  1.000 137.91727 ? 372 SER F CA  1 
ATOM   4153 C C   . SER B 2 337 ? -39.53471 12.57161  20.58948  1.000 144.36490 ? 372 SER F C   1 
ATOM   4154 O O   . SER B 2 337 ? -40.47547 11.82202  20.30776  1.000 144.17681 ? 372 SER F O   1 
ATOM   4155 C CB  . SER B 2 337 ? -38.22463 12.93146  22.70103  1.000 130.46740 ? 372 SER F CB  1 
ATOM   4156 O OG  . SER B 2 337 ? -37.90755 11.56113  22.51430  1.000 130.34021 ? 372 SER F OG  1 
ATOM   4157 N N   . LEU B 2 338 ? -38.50383 12.79377  19.78137  1.000 143.95392 ? 373 LEU F N   1 
ATOM   4158 C CA  . LEU B 2 338 ? -38.40260 12.25768  18.43449  1.000 133.89250 ? 373 LEU F CA  1 
ATOM   4159 C C   . LEU B 2 338 ? -37.03007 11.62458  18.25659  1.000 134.33456 ? 373 LEU F C   1 
ATOM   4160 O O   . LEU B 2 338 ? -36.01632 12.19154  18.67772  1.000 132.04057 ? 373 LEU F O   1 
ATOM   4161 C CB  . LEU B 2 338 ? -38.61453 13.36315  17.38867  1.000 131.86169 ? 373 LEU F CB  1 
ATOM   4162 C CG  . LEU B 2 338 ? -39.87258 14.22495  17.57251  1.000 122.12381 ? 373 LEU F CG  1 
ATOM   4163 C CD1 . LEU B 2 338 ? -39.81047 15.52688  16.76189  1.000 119.80560 ? 373 LEU F CD1 1 
ATOM   4164 C CD2 . LEU B 2 338 ? -41.14430 13.42864  17.25219  1.000 122.52972 ? 373 LEU F CD2 1 
ATOM   4165 N N   . THR B 2 339 ? -36.99827 10.44836  17.63971  1.000 142.63212 ? 374 THR F N   1 
ATOM   4166 C CA  . THR B 2 339 ? -35.75284 9.73878   17.38034  1.000 150.30712 ? 374 THR F CA  1 
ATOM   4167 C C   . THR B 2 339 ? -35.39159 9.89139   15.90825  1.000 164.73522 ? 374 THR F C   1 
ATOM   4168 O O   . THR B 2 339 ? -36.13347 9.43975   15.02870  1.000 172.10178 ? 374 THR F O   1 
ATOM   4169 C CB  . THR B 2 339 ? -35.86535 8.26503   17.77740  1.000 144.51309 ? 374 THR F CB  1 
ATOM   4170 O OG1 . THR B 2 339 ? -37.18250 7.77667   17.48706  1.000 149.09897 ? 374 THR F OG1 1 
ATOM   4171 C CG2 . THR B 2 339 ? -35.59372 8.10154   19.26252  1.000 133.44399 ? 374 THR F CG2 1 
ATOM   4172 N N   . LEU B 2 340 ? -34.24859 10.52362  15.64990  1.000 163.48556 ? 375 LEU F N   1 
ATOM   4173 C CA  . LEU B 2 340 ? -33.73043 10.79239  14.32025  1.000 159.77911 ? 375 LEU F CA  1 
ATOM   4174 C C   . LEU B 2 340 ? -32.35012 10.17016  14.14797  1.000 157.60340 ? 375 LEU F C   1 
ATOM   4175 O O   . LEU B 2 340 ? -31.61935 9.98854   15.12771  1.000 155.08695 ? 375 LEU F O   1 
ATOM   4176 C CB  . LEU B 2 340 ? -33.63273 12.29918  14.03374  1.000 156.09755 ? 375 LEU F CB  1 
ATOM   4177 C CG  . LEU B 2 340 ? -34.84333 13.22397  14.16576  1.000 153.70319 ? 375 LEU F CG  1 
ATOM   4178 C CD1 . LEU B 2 340 ? -34.42810 14.65846  13.87518  1.000 146.38204 ? 375 LEU F CD1 1 
ATOM   4179 C CD2 . LEU B 2 340 ? -35.94555 12.79816  13.20814  1.000 156.92270 ? 375 LEU F CD2 1 
ATOM   4180 N N   . PRO B 2 341 ? -31.97045 9.82250   12.91777  1.000 161.15610 ? 376 PRO F N   1 
ATOM   4181 C CA  . PRO B 2 341 ? -30.60384 9.34746   12.68195  1.000 154.56261 ? 376 PRO F CA  1 
ATOM   4182 C C   . PRO B 2 341 ? -29.59131 10.44551  12.97794  1.000 151.90048 ? 376 PRO F C   1 
ATOM   4183 O O   . PRO B 2 341 ? -29.87258 11.63834  12.84549  1.000 154.08629 ? 376 PRO F O   1 
ATOM   4184 C CB  . PRO B 2 341 ? -30.60932 8.96123   11.19754  1.000 159.10844 ? 376 PRO F CB  1 
ATOM   4185 C CG  . PRO B 2 341 ? -31.73178 9.74565   10.60580  1.000 165.14114 ? 376 PRO F CG  1 
ATOM   4186 C CD  . PRO B 2 341 ? -32.77348 9.82820   11.68248  1.000 164.63840 ? 376 PRO F CD  1 
ATOM   4187 N N   . SER B 2 342 ? -28.39529 10.01915  13.38407  1.000 144.27573 ? 377 SER F N   1 
ATOM   4188 C CA  . SER B 2 342 ? -27.30426 10.91831  13.75045  1.000 147.24320 ? 377 SER F CA  1 
ATOM   4189 C C   . SER B 2 342 ? -26.81589 11.79743  12.60455  1.000 152.90707 ? 377 SER F C   1 
ATOM   4190 O O   . SER B 2 342 ? -26.19638 12.84394  12.86909  1.000 151.57173 ? 377 SER F O   1 
ATOM   4191 C CB  . SER B 2 342 ? -26.13591 10.09960  14.29622  1.000 138.84856 ? 377 SER F CB  1 
ATOM   4192 O OG  . SER B 2 342 ? -25.67172 9.18097   13.32327  1.000 136.19624 ? 377 SER F OG  1 
ATOM   4193 N N   . GLU B 2 343 ? -27.20107 11.50153  11.36095  1.000 156.44163 ? 378 GLU F N   1 
ATOM   4194 C CA  . GLU B 2 343 ? -26.73062 12.36718  10.29343  1.000 158.52041 ? 378 GLU F CA  1 
ATOM   4195 C C   . GLU B 2 343 ? -27.38498 13.73512  10.33798  1.000 163.83426 ? 378 GLU F C   1 
ATOM   4196 O O   . GLU B 2 343 ? -26.91455 14.64803  9.64609   1.000 167.06052 ? 378 GLU F O   1 
ATOM   4197 C CB  . GLU B 2 343 ? -27.04716 11.72151  8.93907   1.000 156.96067 ? 378 GLU F CB  1 
ATOM   4198 C CG  . GLU B 2 343 ? -26.21164 10.51145  8.57472   1.000 154.41585 ? 378 GLU F CG  1 
ATOM   4199 C CD  . GLU B 2 343 ? -27.03053 9.45967   7.84094   1.000 153.29681 ? 378 GLU F CD  1 
ATOM   4200 O OE1 . GLU B 2 343 ? -28.21858 9.72061   7.54813   1.000 158.08263 ? 378 GLU F OE1 1 
ATOM   4201 O OE2 . GLU B 2 343 ? -26.49068 8.36998   7.56218   1.000 145.21112 ? 378 GLU F OE2 1 
ATOM   4202 N N   . VAL B 2 344 ? -28.39444 13.92188  11.19408  1.000 160.99843 ? 379 VAL F N   1 
ATOM   4203 C CA  . VAL B 2 344 ? -29.03331 15.22221  11.28371  1.000 158.45586 ? 379 VAL F CA  1 
ATOM   4204 C C   . VAL B 2 344 ? -28.07346 16.24193  11.87507  1.000 156.70616 ? 379 VAL F C   1 
ATOM   4205 O O   . VAL B 2 344 ? -28.16897 17.43524  11.55240  1.000 159.75036 ? 379 VAL F O   1 
ATOM   4206 C CB  . VAL B 2 344 ? -30.32755 15.14688  12.11360  1.000 148.40217 ? 379 VAL F CB  1 
ATOM   4207 C CG1 . VAL B 2 344 ? -29.99818 14.97986  13.57685  1.000 150.67922 ? 379 VAL F CG1 1 
ATOM   4208 C CG2 . VAL B 2 344 ? -31.16629 16.40648  11.92118  1.000 139.12773 ? 379 VAL F CG2 1 
ATOM   4209 N N   . ASN B 2 345 ? -27.05681 15.79186  12.63047  1.000 152.30633 ? 380 ASN F N   1 
ATOM   4210 C CA  . ASN B 2 345 ? -26.12406 16.78127  13.16643  1.000 155.90211 ? 380 ASN F CA  1 
ATOM   4211 C C   . ASN B 2 345 ? -25.24107 17.35266  12.07380  1.000 155.92269 ? 380 ASN F C   1 
ATOM   4212 O O   . ASN B 2 345 ? -24.77210 18.49521  12.18075  1.000 152.93529 ? 380 ASN F O   1 
ATOM   4213 C CB  . ASN B 2 345 ? -25.24186 16.17171  14.24815  1.000 166.13507 ? 380 ASN F CB  1 
ATOM   4214 C CG  . ASN B 2 345 ? -25.72049 16.49850  15.65324  1.000 187.54568 ? 380 ASN F CG  1 
ATOM   4215 O OD1 . ASN B 2 345 ? -26.33193 17.52936  15.88705  1.000 190.21860 ? 380 ASN F OD1 1 
ATOM   4216 N ND2 . ASN B 2 345 ? -25.42834 15.60337  16.60607  1.000 187.09759 ? 380 ASN F ND2 1 
ATOM   4217 N N   . LEU B 2 346 ? -25.16686 16.67526  10.94132  1.000 158.61949 ? 381 LEU F N   1 
ATOM   4218 C CA  . LEU B 2 346 ? -24.32948 17.17698  9.86726   1.000 151.90242 ? 381 LEU F CA  1 
ATOM   4219 C C   . LEU B 2 346 ? -25.03271 18.30697  9.13899   1.000 148.84469 ? 381 LEU F C   1 
ATOM   4220 O O   . LEU B 2 346 ? -24.45707 18.89951  8.21584   1.000 153.87719 ? 381 LEU F O   1 
ATOM   4221 C CB  . LEU B 2 346 ? -23.93631 16.03136  8.93568   1.000 151.90898 ? 381 LEU F CB  1 
ATOM   4222 C CG  . LEU B 2 346 ? -22.86747 15.21917  9.66950   1.000 141.08931 ? 381 LEU F CG  1 
ATOM   4223 C CD1 . LEU B 2 346 ? -22.57844 13.89400  8.97796   1.000 130.30682 ? 381 LEU F CD1 1 
ATOM   4224 C CD2 . LEU B 2 346 ? -21.59160 16.03532  9.86784   1.000 122.40097 ? 381 LEU F CD2 1 
ATOM   4225 N N   . CYS B 2 347 ? -26.26759 18.61256  9.55462   1.000 147.95598 ? 382 CYS F N   1 
ATOM   4226 C CA  . CYS B 2 347 ? -26.98436 19.76820  9.03206   1.000 151.85239 ? 382 CYS F CA  1 
ATOM   4227 C C   . CYS B 2 347 ? -26.37076 21.07132  9.53347   1.000 152.30514 ? 382 CYS F C   1 
ATOM   4228 O O   . CYS B 2 347 ? -26.60877 22.12538  8.93188   1.000 155.78071 ? 382 CYS F O   1 
ATOM   4229 C CB  . CYS B 2 347 ? -28.45845 19.68829  9.42504   1.000 151.18354 ? 382 CYS F CB  1 
ATOM   4230 S SG  . CYS B 2 347 ? -29.43490 18.35004  8.66943   1.000 170.22211 ? 382 CYS F SG  1 
ATOM   4231 N N   . ASN B 2 348 ? -25.57836 21.01805  10.61416  1.000 152.07644 ? 383 ASN F N   1 
ATOM   4232 C CA  . ASN B 2 348 ? -24.97592 22.24965  11.11402  1.000 150.54839 ? 383 ASN F CA  1 
ATOM   4233 C C   . ASN B 2 348 ? -23.76947 22.72037  10.31837  1.000 153.36415 ? 383 ASN F C   1 
ATOM   4234 O O   . ASN B 2 348 ? -23.46693 23.92576  10.32990  1.000 151.72239 ? 383 ASN F O   1 
ATOM   4235 C CB  . ASN B 2 348 ? -24.60017 22.10860  12.58621  1.000 146.20063 ? 383 ASN F CB  1 
ATOM   4236 C CG  . ASN B 2 348 ? -25.75491 21.63843  13.43228  1.000 153.44031 ? 383 ASN F CG  1 
ATOM   4237 O OD1 . ASN B 2 348 ? -26.72191 22.37220  13.63854  1.000 151.80631 ? 383 ASN F OD1 1 
ATOM   4238 N ND2 . ASN B 2 348 ? -25.64926 20.43158  13.95875  1.000 155.09366 ? 383 ASN F ND2 1 
ATOM   4239 N N   . VAL B 2 349 ? -23.07206 21.82470  9.62183   1.000 154.43598 ? 384 VAL F N   1 
ATOM   4240 C CA  . VAL B 2 349 ? -21.90699 22.22367  8.84426   1.000 149.90820 ? 384 VAL F CA  1 
ATOM   4241 C C   . VAL B 2 349 ? -22.19673 22.25002  7.34363   1.000 152.07794 ? 384 VAL F C   1 
ATOM   4242 O O   . VAL B 2 349 ? -21.57453 23.03738  6.61449   1.000 154.44610 ? 384 VAL F O   1 
ATOM   4243 C CB  . VAL B 2 349 ? -20.69524 21.30162  9.13917   1.000 144.26849 ? 384 VAL F CB  1 
ATOM   4244 C CG1 . VAL B 2 349 ? -20.45856 21.17084  10.63612  1.000 144.60899 ? 384 VAL F CG1 1 
ATOM   4245 C CG2 . VAL B 2 349 ? -20.89286 19.91536  8.51655   1.000 136.73709 ? 384 VAL F CG2 1 
ATOM   4246 N N   . ASP B 2 350 ? -23.10735 21.41049  6.85796   1.000 153.60750 ? 385 ASP F N   1 
ATOM   4247 C CA  . ASP B 2 350 ? -23.44398 21.37516  5.43501   1.000 153.78755 ? 385 ASP F CA  1 
ATOM   4248 C C   . ASP B 2 350 ? -24.94173 21.09410  5.34436   1.000 157.07166 ? 385 ASP F C   1 
ATOM   4249 O O   . ASP B 2 350 ? -25.35277 19.93604  5.42916   1.000 155.85497 ? 385 ASP F O   1 
ATOM   4250 C CB  . ASP B 2 350 ? -22.60916 20.35231  4.67782   1.000 147.79536 ? 385 ASP F CB  1 
ATOM   4251 C CG  . ASP B 2 350 ? -22.90236 20.35575  3.18818   1.000 151.28923 ? 385 ASP F CG  1 
ATOM   4252 O OD1 . ASP B 2 350 ? -23.54540 21.32069  2.71651   1.000 152.73598 ? 385 ASP F OD1 1 
ATOM   4253 O OD2 . ASP B 2 350 ? -22.46184 19.42626  2.47822   1.000 148.21567 ? 385 ASP F OD2 1 
ATOM   4254 N N   . ILE B 2 351 ? -25.75035 22.15019  5.17482   1.000 163.09355 ? 386 ILE F N   1 
ATOM   4255 C CA  . ILE B 2 351 ? -27.20901 22.00923  5.16344   1.000 166.07126 ? 386 ILE F CA  1 
ATOM   4256 C C   . ILE B 2 351 ? -27.72825 21.63498  3.77692   1.000 174.39894 ? 386 ILE F C   1 
ATOM   4257 O O   . ILE B 2 351 ? -28.82682 21.06796  3.66730   1.000 172.60277 ? 386 ILE F O   1 
ATOM   4258 C CB  . ILE B 2 351 ? -27.92018 23.29076  5.65586   1.000 158.65901 ? 386 ILE F CB  1 
ATOM   4259 C CG1 . ILE B 2 351 ? -29.41476 23.03971  5.92953   1.000 153.94947 ? 386 ILE F CG1 1 
ATOM   4260 C CG2 . ILE B 2 351 ? -27.75571 24.43835  4.65644   1.000 152.04449 ? 386 ILE F CG2 1 
ATOM   4261 C CD1 . ILE B 2 351 ? -30.14822 24.23347  6.52303   1.000 152.46561 ? 386 ILE F CD1 1 
ATOM   4262 N N   . PHE B 2 352 ? -26.96269 21.90540  2.72119   1.000 176.18713 ? 387 PHE F N   1 
ATOM   4263 C CA  . PHE B 2 352 ? -27.35869 21.63080  1.34848   1.000 161.51829 ? 387 PHE F CA  1 
ATOM   4264 C C   . PHE B 2 352 ? -27.03565 20.19969  0.96655   1.000 165.41577 ? 387 PHE F C   1 
ATOM   4265 O O   . PHE B 2 352 ? -27.14870 19.84221  -0.21029  1.000 172.04764 ? 387 PHE F O   1 
ATOM   4266 C CB  . PHE B 2 352 ? -26.65027 22.55744  0.35143   1.000 148.81823 ? 387 PHE F CB  1 
ATOM   4267 C CG  . PHE B 2 352 ? -27.15593 23.96760  0.34191   1.000 141.16426 ? 387 PHE F CG  1 
ATOM   4268 C CD1 . PHE B 2 352 ? -28.51238 24.23023  0.35735   1.000 142.72748 ? 387 PHE F CD1 1 
ATOM   4269 C CD2 . PHE B 2 352 ? -26.27091 25.03040  0.22186   1.000 139.06692 ? 387 PHE F CD2 1 
ATOM   4270 C CE1 . PHE B 2 352 ? -28.98131 25.52861  0.31518   1.000 139.49257 ? 387 PHE F CE1 1 
ATOM   4271 C CE2 . PHE B 2 352 ? -26.73289 26.33139  0.17208   1.000 138.36637 ? 387 PHE F CE2 1 
ATOM   4272 C CZ  . PHE B 2 352 ? -28.09142 26.58048  0.21868   1.000 137.47789 ? 387 PHE F CZ  1 
ATOM   4273 N N   . ASN B 2 353 ? -26.66536 19.36990  1.93954   1.000 165.70891 ? 388 ASN F N   1 
ATOM   4274 C CA  . ASN B 2 353 ? -26.28147 18.00375  1.64691   1.000 166.15363 ? 388 ASN F CA  1 
ATOM   4275 C C   . ASN B 2 353 ? -27.49768 17.10225  1.60253   1.000 174.87413 ? 388 ASN F C   1 
ATOM   4276 O O   . ASN B 2 353 ? -28.22451 17.00016  2.60250   1.000 178.08737 ? 388 ASN F O   1 
ATOM   4277 C CB  . ASN B 2 353 ? -25.31456 17.46932  2.68668   1.000 155.21681 ? 388 ASN F CB  1 
ATOM   4278 C CG  . ASN B 2 353 ? -23.96023 17.14098  2.10901   1.000 153.26084 ? 388 ASN F CG  1 
ATOM   4279 O OD1 . ASN B 2 353 ? -23.83665 16.81037  0.92995   1.000 154.10872 ? 388 ASN F OD1 1 
ATOM   4280 N ND2 . ASN B 2 353 ? -22.92740 17.24536  2.93543   1.000 150.32013 ? 388 ASN F ND2 1 
ATOM   4281 N N   . PRO B 2 354 ? -27.74312 16.43600  0.47465   1.000 178.38798 ? 389 PRO F N   1 
ATOM   4282 C CA  . PRO B 2 354 ? -28.87829 15.52269  0.36385   1.000 174.86772 ? 389 PRO F CA  1 
ATOM   4283 C C   . PRO B 2 354 ? -28.73173 14.27145  1.19727   1.000 173.51459 ? 389 PRO F C   1 
ATOM   4284 O O   . PRO B 2 354 ? -29.69479 13.49816  1.25280   1.000 170.69798 ? 389 PRO F O   1 
ATOM   4285 C CB  . PRO B 2 354 ? -28.92496 15.20347  -1.12526  1.000 178.90374 ? 389 PRO F CB  1 
ATOM   4286 C CG  . PRO B 2 354 ? -27.49340 15.25245  -1.52814  1.000 177.24954 ? 389 PRO F CG  1 
ATOM   4287 C CD  . PRO B 2 354 ? -26.85262 16.34272  -0.69325  1.000 175.73506 ? 389 PRO F CD  1 
ATOM   4288 N N   . LYS B 2 355 ? -27.58537 14.02059  1.85183   1.000 169.60668 ? 390 LYS F N   1 
ATOM   4289 C CA  . LYS B 2 355 ? -27.51925 12.76436  2.58963   1.000 159.97688 ? 390 LYS F CA  1 
ATOM   4290 C C   . LYS B 2 355 ? -28.52556 12.77732  3.73437   1.000 169.63547 ? 390 LYS F C   1 
ATOM   4291 O O   . LYS B 2 355 ? -28.95075 11.70398  4.18235   1.000 167.31745 ? 390 LYS F O   1 
ATOM   4292 C CB  . LYS B 2 355 ? -26.10270 12.57557  3.14737   1.000 135.09742 ? 390 LYS F CB  1 
ATOM   4293 C CG  . LYS B 2 355 ? -25.78761 11.28201  3.89837   1.000 116.91640 ? 390 LYS F CG  1 
ATOM   4294 C CD  . LYS B 2 355 ? -26.11455 10.02462  3.12692   1.000 118.94808 ? 390 LYS F CD  1 
ATOM   4295 C CE  . LYS B 2 355 ? -25.26695 9.94155   1.85977   1.000 108.45680 ? 390 LYS F CE  1 
ATOM   4296 N NZ  . LYS B 2 355 ? -25.63316 8.74048   1.06140   1.000 82.27531  ? 390 LYS F NZ  1 
ATOM   4297 N N   . TYR B 2 356 ? -28.88877 13.96274  4.25865   1.000 177.17764 ? 391 TYR F N   1 
ATOM   4298 C CA  . TYR B 2 356 ? -29.95394 14.05067  5.24852   1.000 173.85282 ? 391 TYR F CA  1 
ATOM   4299 C C   . TYR B 2 356 ? -30.85277 15.21642  4.83687   1.000 174.15723 ? 391 TYR F C   1 
ATOM   4300 O O   . TYR B 2 356 ? -30.34925 16.30025  4.50709   1.000 173.88065 ? 391 TYR F O   1 
ATOM   4301 C CB  . TYR B 2 356 ? -29.43075 14.23674  6.67078   1.000 172.40241 ? 391 TYR F CB  1 
ATOM   4302 C CG  . TYR B 2 356 ? -30.55817 14.13109  7.65765   1.000 176.98031 ? 391 TYR F CG  1 
ATOM   4303 C CD1 . TYR B 2 356 ? -31.01418 12.88386  8.05956   1.000 174.60043 ? 391 TYR F CD1 1 
ATOM   4304 C CD2 . TYR B 2 356 ? -31.21156 15.25654  8.13458   1.000 175.39277 ? 391 TYR F CD2 1 
ATOM   4305 C CE1 . TYR B 2 356 ? -32.04448 12.76061  8.94418   1.000 169.53663 ? 391 TYR F CE1 1 
ATOM   4306 C CE2 . TYR B 2 356 ? -32.26281 15.14040  9.02402   1.000 165.30623 ? 391 TYR F CE2 1 
ATOM   4307 C CZ  . TYR B 2 356 ? -32.67101 13.88685  9.43024   1.000 163.25041 ? 391 TYR F CZ  1 
ATOM   4308 O OH  . TYR B 2 356 ? -33.71378 13.74352  10.32123  1.000 161.93506 ? 391 TYR F OH  1 
ATOM   4309 N N   . ASP B 2 357 ? -32.15841 14.98839  4.80738   1.000 177.80339 ? 392 ASP F N   1 
ATOM   4310 C CA  . ASP B 2 357 ? -33.15694 15.99713  4.41518   1.000 179.06348 ? 392 ASP F CA  1 
ATOM   4311 C C   . ASP B 2 357 ? -33.33130 16.94209  5.62230   1.000 177.40814 ? 392 ASP F C   1 
ATOM   4312 O O   . ASP B 2 357 ? -34.20076 16.75672  6.47739   1.000 184.04467 ? 392 ASP F O   1 
ATOM   4313 C CB  . ASP B 2 357 ? -34.41644 15.36891  3.79972   1.000 178.58754 ? 392 ASP F CB  1 
ATOM   4314 C CG  . ASP B 2 357 ? -35.03480 14.29877  4.63309   1.000 175.59343 ? 392 ASP F CG  1 
ATOM   4315 O OD1 . ASP B 2 357 ? -34.56842 13.12867  4.58698   1.000 164.11538 ? 392 ASP F OD1 1 
ATOM   4316 O OD2 . ASP B 2 357 ? -36.04147 14.62782  5.30610   1.000 181.17325 ? 392 ASP F OD2 1 
ATOM   4317 N N   . CYS B 2 358 ? -32.44967 17.94494  5.66186   1.000 171.22141 ? 393 CYS F N   1 
ATOM   4318 C CA  . CYS B 2 358 ? -32.34863 19.05069  6.60477   1.000 164.09648 ? 393 CYS F CA  1 
ATOM   4319 C C   . CYS B 2 358 ? -33.42737 20.09122  6.34686   1.000 155.88065 ? 393 CYS F C   1 
ATOM   4320 O O   . CYS B 2 358 ? -33.39115 20.81567  5.34999   1.000 153.55600 ? 393 CYS F O   1 
ATOM   4321 C CB  . CYS B 2 358 ? -30.98636 19.72119  6.47461   1.000 161.18131 ? 393 CYS F CB  1 
ATOM   4322 S SG  . CYS B 2 358 ? -29.51350 18.70610  6.68880   1.000 168.00933 ? 393 CYS F SG  1 
ATOM   4323 N N   . LYS B 2 359 ? -34.36329 20.20247  7.28696   1.000 160.50423 ? 394 LYS F N   1 
ATOM   4324 C CA  . LYS B 2 359 ? -35.58831 20.97700  7.16413   1.000 162.42624 ? 394 LYS F CA  1 
ATOM   4325 C C   . LYS B 2 359 ? -35.36395 22.40849  7.62628   1.000 153.46035 ? 394 LYS F C   1 
ATOM   4326 O O   . LYS B 2 359 ? -34.61789 22.68499  8.57047   1.000 146.62118 ? 394 LYS F O   1 
ATOM   4327 C CB  . LYS B 2 359 ? -36.66108 20.33505  8.04985   1.000 161.71334 ? 394 LYS F CB  1 
ATOM   4328 C CG  . LYS B 2 359 ? -38.09561 20.81102  7.92067   1.000 162.34156 ? 394 LYS F CG  1 
ATOM   4329 C CD  . LYS B 2 359 ? -39.04824 19.94007  8.73845   1.000 158.91905 ? 394 LYS F CD  1 
ATOM   4330 C CE  . LYS B 2 359 ? -40.48804 20.39280  8.57245   1.000 155.38538 ? 394 LYS F CE  1 
ATOM   4331 N NZ  . LYS B 2 359 ? -40.96574 20.35328  7.16768   1.000 150.08286 ? 394 LYS F NZ  1 
ATOM   4332 N N   . ILE B 2 360 ? -36.05857 23.31299  6.93321   1.000 151.07665 ? 395 ILE F N   1 
ATOM   4333 C CA  . ILE B 2 360 ? -36.02050 24.75682  7.12094   1.000 146.02898 ? 395 ILE F CA  1 
ATOM   4334 C C   . ILE B 2 360 ? -37.42746 25.33643  7.03415   1.000 157.69306 ? 395 ILE F C   1 
ATOM   4335 O O   . ILE B 2 360 ? -38.39020 24.65341  6.67942   1.000 165.36363 ? 395 ILE F O   1 
ATOM   4336 C CB  . ILE B 2 360 ? -35.11906 25.42870  6.06529   1.000 144.32141 ? 395 ILE F CB  1 
ATOM   4337 C CG1 . ILE B 2 360 ? -35.73422 25.20234  4.68119   1.000 162.48686 ? 395 ILE F CG1 1 
ATOM   4338 C CG2 . ILE B 2 360 ? -33.71303 24.85797  6.11248   1.000 137.73507 ? 395 ILE F CG2 1 
ATOM   4339 C CD1 . ILE B 2 360 ? -35.19213 26.10051  3.60803   1.000 164.46147 ? 395 ILE F CD1 1 
ATOM   4340 N N   . MET B 2 361 ? -37.53637 26.61869  7.39059   1.000 154.03808 ? 396 MET F N   1 
ATOM   4341 C CA  . MET B 2 361 ? -38.74190 27.39522  7.14555   1.000 163.26360 ? 396 MET F CA  1 
ATOM   4342 C C   . MET B 2 361 ? -38.35294 28.65842  6.38988   1.000 165.44660 ? 396 MET F C   1 
ATOM   4343 O O   . MET B 2 361 ? -37.27143 29.21566  6.59512   1.000 162.75292 ? 396 MET F O   1 
ATOM   4344 C CB  . MET B 2 361 ? -39.43019 27.77559  8.46593   1.000 163.57321 ? 396 MET F CB  1 
ATOM   4345 C CG  . MET B 2 361 ? -40.77007 28.47304  8.33412   1.000 170.37223 ? 396 MET F CG  1 
ATOM   4346 S SD  . MET B 2 361 ? -41.57383 28.59647  9.94410   1.000 173.27750 ? 396 MET F SD  1 
ATOM   4347 C CE  . MET B 2 361 ? -41.76287 26.86543  10.36795  1.000 164.47808 ? 396 MET F CE  1 
ATOM   4348 N N   . THR B 2 362 ? -39.23876 29.08153  5.49265   1.000 172.34884 ? 397 THR F N   1 
ATOM   4349 C CA  . THR B 2 362 ? -39.03830 30.20915  4.59294   1.000 167.92508 ? 397 THR F CA  1 
ATOM   4350 C C   . THR B 2 362 ? -40.13018 31.26059  4.74376   1.000 166.60212 ? 397 THR F C   1 
ATOM   4351 O O   . THR B 2 362 ? -41.24189 30.96847  5.19731   1.000 164.56564 ? 397 THR F O   1 
ATOM   4352 C CB  . THR B 2 362 ? -39.00690 29.73692  3.13855   1.000 170.11413 ? 397 THR F CB  1 
ATOM   4353 O OG1 . THR B 2 362 ? -40.25996 29.11806  2.82321   1.000 175.99968 ? 397 THR F OG1 1 
ATOM   4354 C CG2 . THR B 2 362 ? -37.89895 28.71856  2.95496   1.000 165.34848 ? 397 THR F CG2 1 
ATOM   4355 N N   . SER B 2 363 ? -39.80422 32.49061  4.35222   1.000 165.97835 ? 398 SER F N   1 
ATOM   4356 C CA  . SER B 2 363 ? -40.79038 33.57121  4.38016   1.000 164.95411 ? 398 SER F CA  1 
ATOM   4357 C C   . SER B 2 363 ? -40.22521 34.74738  3.59036   1.000 169.81661 ? 398 SER F C   1 
ATOM   4358 O O   . SER B 2 363 ? -39.15240 34.65309  2.98617   1.000 170.39618 ? 398 SER F O   1 
ATOM   4359 C CB  . SER B 2 363 ? -41.14210 33.98217  5.81045   1.000 158.44016 ? 398 SER F CB  1 
ATOM   4360 O OG  . SER B 2 363 ? -40.06657 34.67999  6.40707   1.000 164.66906 ? 398 SER F OG  1 
ATOM   4361 N N   . LYS B 2 364 ? -40.97896 35.84762  3.56171   1.000 173.68147 ? 399 LYS F N   1 
ATOM   4362 C CA  . LYS B 2 364 ? -40.50623 37.09307  2.97526   1.000 175.41388 ? 399 LYS F CA  1 
ATOM   4363 C C   . LYS B 2 364 ? -40.58812 38.21821  4.00707   1.000 176.01174 ? 399 LYS F C   1 
ATOM   4364 O O   . LYS B 2 364 ? -40.73885 39.39736  3.67027   1.000 175.40393 ? 399 LYS F O   1 
ATOM   4365 C CB  . LYS B 2 364 ? -41.31170 37.36875  1.69602   1.000 175.47638 ? 399 LYS F CB  1 
ATOM   4366 C CG  . LYS B 2 364 ? -40.55331 38.03347  0.54549   1.000 169.39845 ? 399 LYS F CG  1 
ATOM   4367 C CD  . LYS B 2 364 ? -41.35661 38.02513  -0.76316  1.000 154.71922 ? 399 LYS F CD  1 
ATOM   4368 C CE  . LYS B 2 364 ? -42.58850 38.90159  -0.75503  1.000 147.82701 ? 399 LYS F CE  1 
ATOM   4369 N NZ  . LYS B 2 364 ? -42.26438 40.35398  -0.68980  1.000 145.75210 ? 399 LYS F NZ  1 
ATOM   4370 N N   . THR B 2 365 ? -40.49954 37.82771  5.28642   1.000 172.38012 ? 400 THR F N   1 
ATOM   4371 C CA  . THR B 2 365 ? -40.63789 38.67782  6.47385   1.000 163.86528 ? 400 THR F CA  1 
ATOM   4372 C C   . THR B 2 365 ? -39.26491 38.94411  7.09416   1.000 163.21555 ? 400 THR F C   1 
ATOM   4373 O O   . THR B 2 365 ? -38.77233 38.13839  7.88683   1.000 169.68154 ? 400 THR F O   1 
ATOM   4374 C CB  . THR B 2 365 ? -41.59211 38.04479  7.48022   1.000 163.49896 ? 400 THR F CB  1 
ATOM   4375 O OG1 . THR B 2 365 ? -42.85400 37.80207  6.84649   1.000 172.75115 ? 400 THR F OG1 1 
ATOM   4376 C CG2 . THR B 2 365 ? -41.80599 38.97831  8.66131   1.000 156.23155 ? 400 THR F CG2 1 
ATOM   4377 N N   . ASP B 2 366 ? -38.63977 40.07090  6.74667   1.000 166.45844 ? 401 ASP F N   1 
ATOM   4378 C CA  . ASP B 2 366 ? -37.30320 40.39877  7.25903   1.000 172.93889 ? 401 ASP F CA  1 
ATOM   4379 C C   . ASP B 2 366 ? -37.41161 41.27959  8.50738   1.000 189.05369 ? 401 ASP F C   1 
ATOM   4380 O O   . ASP B 2 366 ? -37.22672 42.49782  8.47706   1.000 195.52659 ? 401 ASP F O   1 
ATOM   4381 C CB  . ASP B 2 366 ? -36.44955 41.04740  6.16794   1.000 167.99217 ? 401 ASP F CB  1 
ATOM   4382 C CG  . ASP B 2 366 ? -37.15495 42.19887  5.44496   1.000 176.33099 ? 401 ASP F CG  1 
ATOM   4383 O OD1 . ASP B 2 366 ? -38.07371 42.82615  6.01374   1.000 180.01333 ? 401 ASP F OD1 1 
ATOM   4384 O OD2 . ASP B 2 366 ? -36.77273 42.48410  4.28906   1.000 168.80670 ? 401 ASP F OD2 1 
ATOM   4385 N N   . VAL B 2 367 ? -37.69176 40.62651  9.64157   1.000 192.86551 ? 402 VAL F N   1 
ATOM   4386 C CA  . VAL B 2 367 ? -37.76635 41.27865  10.94854  1.000 184.06372 ? 402 VAL F CA  1 
ATOM   4387 C C   . VAL B 2 367 ? -36.56206 40.86719  11.78996  1.000 175.66959 ? 402 VAL F C   1 
ATOM   4388 O O   . VAL B 2 367 ? -36.18397 39.69020  11.83009  1.000 170.26105 ? 402 VAL F O   1 
ATOM   4389 C CB  . VAL B 2 367 ? -39.08266 40.92919  11.67436  1.000 177.55678 ? 402 VAL F CB  1 
ATOM   4390 C CG1 . VAL B 2 367 ? -40.23205 41.76613  11.13629  1.000 177.62074 ? 402 VAL F CG1 1 
ATOM   4391 C CG2 . VAL B 2 367 ? -39.39653 39.45069  11.52092  1.000 175.16062 ? 402 VAL F CG2 1 
ATOM   4392 N N   . SER B 2 368 ? -35.96433 41.85157  12.46042  1.000 175.42223 ? 403 SER F N   1 
ATOM   4393 C CA  . SER B 2 368 ? -34.75885 41.65696  13.25823  1.000 178.78880 ? 403 SER F CA  1 
ATOM   4394 C C   . SER B 2 368 ? -35.02383 40.86504  14.53408  1.000 183.65875 ? 403 SER F C   1 
ATOM   4395 O O   . SER B 2 368 ? -36.10763 40.93191  15.12174  1.000 181.71305 ? 403 SER F O   1 
ATOM   4396 C CB  . SER B 2 368 ? -34.15501 43.01069  13.63349  1.000 177.53040 ? 403 SER F CB  1 
ATOM   4397 O OG  . SER B 2 368 ? -33.71963 43.72166  12.48810  1.000 182.84736 ? 403 SER F OG  1 
ATOM   4398 N N   . SER B 2 369 ? -34.00896 40.11614  14.97016  1.000 189.47924 ? 404 SER F N   1 
ATOM   4399 C CA  . SER B 2 369 ? -34.13479 39.34327  16.20102  1.000 182.35466 ? 404 SER F CA  1 
ATOM   4400 C C   . SER B 2 369 ? -32.74993 38.96141  16.70569  1.000 168.17073 ? 404 SER F C   1 
ATOM   4401 O O   . SER B 2 369 ? -31.73685 39.15216  16.02863  1.000 169.14293 ? 404 SER F O   1 
ATOM   4402 C CB  . SER B 2 369 ? -34.98674 38.08268  15.99259  1.000 188.16847 ? 404 SER F CB  1 
ATOM   4403 O OG  . SER B 2 369 ? -34.41360 37.22819  15.01531  1.000 178.32320 ? 404 SER F OG  1 
ATOM   4404 N N   . SER B 2 370 ? -32.71547 38.45793  17.93401  1.000 157.91822 ? 405 SER F N   1 
ATOM   4405 C CA  . SER B 2 370 ? -31.47855 37.95775  18.50781  1.000 146.64123 ? 405 SER F CA  1 
ATOM   4406 C C   . SER B 2 370 ? -31.78840 36.71940  19.33211  1.000 141.02357 ? 405 SER F C   1 
ATOM   4407 O O   . SER B 2 370 ? -32.88366 36.57470  19.88093  1.000 138.28951 ? 405 SER F O   1 
ATOM   4408 C CB  . SER B 2 370 ? -30.76741 39.00504  19.37838  1.000 137.74930 ? 405 SER F CB  1 
ATOM   4409 O OG  . SER B 2 370 ? -29.56106 38.48263  19.91078  1.000 134.70312 ? 405 SER F OG  1 
ATOM   4410 N N   . VAL B 2 371 ? -30.80640 35.83504  19.42226  1.000 135.20718 ? 406 VAL F N   1 
ATOM   4411 C CA  . VAL B 2 371 ? -30.91824 34.63123  20.22077  1.000 132.87282 ? 406 VAL F CA  1 
ATOM   4412 C C   . VAL B 2 371 ? -29.67657 34.60088  21.08894  1.000 134.79290 ? 406 VAL F C   1 
ATOM   4413 O O   . VAL B 2 371 ? -28.55455 34.55511  20.57305  1.000 141.32387 ? 406 VAL F O   1 
ATOM   4414 C CB  . VAL B 2 371 ? -31.03540 33.35414  19.36946  1.000 130.34370 ? 406 VAL F CB  1 
ATOM   4415 C CG1 . VAL B 2 371 ? -31.08543 32.12375  20.25863  1.000 122.36920 ? 406 VAL F CG1 1 
ATOM   4416 C CG2 . VAL B 2 371 ? -32.28945 33.40476  18.51233  1.000 133.43813 ? 406 VAL F CG2 1 
ATOM   4417 N N   . ILE B 2 372 ? -29.86554 34.58429  22.40127  1.000 130.93445 ? 407 ILE F N   1 
ATOM   4418 C CA  . ILE B 2 372 ? -28.72866 34.47061  23.31306  1.000 120.14756 ? 407 ILE F CA  1 
ATOM   4419 C C   . ILE B 2 372 ? -28.36094 32.99377  23.38115  1.000 119.78047 ? 407 ILE F C   1 
ATOM   4420 O O   . ILE B 2 372 ? -29.17106 32.17050  23.82141  1.000 119.24162 ? 407 ILE F O   1 
ATOM   4421 C CB  . ILE B 2 372 ? -29.04530 35.03212  24.70726  1.000 118.40742 ? 407 ILE F CB  1 
ATOM   4422 C CG1 . ILE B 2 372 ? -29.34115 36.53697  24.63167  1.000 122.73596 ? 407 ILE F CG1 1 
ATOM   4423 C CG2 . ILE B 2 372 ? -27.88339 34.75025  25.63573  1.000 124.77821 ? 407 ILE F CG2 1 
ATOM   4424 C CD1 . ILE B 2 372 ? -28.19203 37.34804  24.05489  1.000 126.99450 ? 407 ILE F CD1 1 
ATOM   4425 N N   . THR B 2 373 ? -27.15291 32.64141  22.93793  1.000 121.76425 ? 408 THR F N   1 
ATOM   4426 C CA  . THR B 2 373 ? -26.84704 31.23105  22.98493  1.000 123.15594 ? 408 THR F CA  1 
ATOM   4427 C C   . THR B 2 373 ? -26.15390 30.96179  24.31760  1.000 121.62126 ? 408 THR F C   1 
ATOM   4428 O O   . THR B 2 373 ? -25.71559 31.90471  25.00578  1.000 114.39259 ? 408 THR F O   1 
ATOM   4429 C CB  . THR B 2 373 ? -25.96279 30.80550  21.80070  1.000 120.80685 ? 408 THR F CB  1 
ATOM   4430 O OG1 . THR B 2 373 ? -24.60701 31.22445  22.00828  1.000 115.15268 ? 408 THR F OG1 1 
ATOM   4431 C CG2 . THR B 2 373 ? -26.49139 31.40315  20.48413  1.000 126.79014 ? 408 THR F CG2 1 
ATOM   4432 N N   . SER B 2 374 ? -25.65398 29.73687  24.45228  1.000 125.42865 ? 409 SER F N   1 
ATOM   4433 C CA  . SER B 2 374 ? -25.07868 29.32139  25.73207  1.000 128.81590 ? 409 SER F CA  1 
ATOM   4434 C C   . SER B 2 374 ? -23.74847 29.97494  25.99042  1.000 130.28572 ? 409 SER F C   1 
ATOM   4435 O O   . SER B 2 374 ? -23.41015 30.27538  27.13715  1.000 139.27289 ? 409 SER F O   1 
ATOM   4436 C CB  . SER B 2 374 ? -24.99209 27.80203  25.78888  1.000 122.74009 ? 409 SER F CB  1 
ATOM   4437 O OG  . SER B 2 374 ? -26.26410 27.23241  25.51987  1.000 120.98951 ? 409 SER F OG  1 
ATOM   4438 N N   . LEU B 2 375 ? -23.01220 30.24795  24.94787  1.000 127.97113 ? 410 LEU F N   1 
ATOM   4439 C CA  . LEU B 2 375 ? -21.70026 30.81644  25.13725  1.000 124.90381 ? 410 LEU F CA  1 
ATOM   4440 C C   . LEU B 2 375 ? -21.58619 32.09165  24.33079  1.000 132.83905 ? 410 LEU F C   1 
ATOM   4441 O O   . LEU B 2 375 ? -20.46957 32.56084  24.08950  1.000 135.29294 ? 410 LEU F O   1 
ATOM   4442 C CB  . LEU B 2 375 ? -20.65915 29.78677  24.72001  1.000 121.70104 ? 410 LEU F CB  1 
ATOM   4443 C CG  . LEU B 2 375 ? -20.05783 28.93975  25.83360  1.000 128.24793 ? 410 LEU F CG  1 
ATOM   4444 C CD1 . LEU B 2 375 ? -19.14654 27.87938  25.24030  1.000 133.77655 ? 410 LEU F CD1 1 
ATOM   4445 C CD2 . LEU B 2 375 ? -19.23079 29.79492  26.81673  1.000 137.22655 ? 410 LEU F CD2 1 
ATOM   4446 N N   . GLY B 2 376 ? -22.72696 32.65876  23.89049  1.000 138.76261 ? 411 GLY F N   1 
ATOM   4447 C CA  . GLY B 2 376 ? -22.62240 33.87739  23.10498  1.000 137.67750 ? 411 GLY F CA  1 
ATOM   4448 C C   . GLY B 2 376 ? -23.96165 34.40268  22.63325  1.000 136.45195 ? 411 GLY F C   1 
ATOM   4449 O O   . GLY B 2 376 ? -24.93061 34.34541  23.39295  1.000 128.94636 ? 411 GLY F O   1 
ATOM   4450 N N   . ALA B 2 377 ? -24.02502 34.99152  21.43355  1.000 140.87544 ? 412 ALA F N   1 
ATOM   4451 C CA  . ALA B 2 377 ? -25.29951 35.52788  20.95919  1.000 137.60114 ? 412 ALA F CA  1 
ATOM   4452 C C   . ALA B 2 377 ? -25.29470 35.64568  19.44071  1.000 142.23124 ? 412 ALA F C   1 
ATOM   4453 O O   . ALA B 2 377 ? -24.35280 36.20320  18.86340  1.000 144.73873 ? 412 ALA F O   1 
ATOM   4454 C CB  . ALA B 2 377 ? -25.59174 36.89774  21.58814  1.000 123.57487 ? 412 ALA F CB  1 
ATOM   4455 N N   . ILE B 2 378 ? -26.36561 35.13136  18.79890  1.000 142.98059 ? 413 ILE F N   1 
ATOM   4456 C CA  . ILE B 2 378 ? -26.63029 35.32142  17.37358  1.000 139.71081 ? 413 ILE F CA  1 
ATOM   4457 C C   . ILE B 2 378 ? -27.50287 36.55761  17.18901  1.000 142.70246 ? 413 ILE F C   1 
ATOM   4458 O O   . ILE B 2 378 ? -28.47158 36.76351  17.93435  1.000 142.39174 ? 413 ILE F O   1 
ATOM   4459 C CB  . ILE B 2 378 ? -27.30493 34.07080  16.76832  1.000 138.05328 ? 413 ILE F CB  1 
ATOM   4460 C CG1 . ILE B 2 378 ? -26.52150 32.80684  17.12317  1.000 139.84477 ? 413 ILE F CG1 1 
ATOM   4461 C CG2 . ILE B 2 378 ? -27.44950 34.20247  15.25389  1.000 137.04625 ? 413 ILE F CG2 1 
ATOM   4462 C CD1 . ILE B 2 378 ? -27.17332 31.53390  16.64631  1.000 138.53430 ? 413 ILE F CD1 1 
ATOM   4463 N N   . VAL B 2 379 ? -27.16861 37.38785  16.20260  1.000 147.78651 ? 414 VAL F N   1 
ATOM   4464 C CA  . VAL B 2 379 ? -27.91959 38.61272  15.92296  1.000 151.62074 ? 414 VAL F CA  1 
ATOM   4465 C C   . VAL B 2 379 ? -28.27844 38.63506  14.44119  1.000 164.68990 ? 414 VAL F C   1 
ATOM   4466 O O   . VAL B 2 379 ? -27.38267 38.59459  13.58769  1.000 167.34482 ? 414 VAL F O   1 
ATOM   4467 C CB  . VAL B 2 379 ? -27.14217 39.88027  16.31654  1.000 145.76464 ? 414 VAL F CB  1 
ATOM   4468 C CG1 . VAL B 2 379 ? -27.89939 41.12020  15.87046  1.000 149.45451 ? 414 VAL F CG1 1 
ATOM   4469 C CG2 . VAL B 2 379 ? -26.93135 39.91766  17.82037  1.000 154.73395 ? 414 VAL F CG2 1 
ATOM   4470 N N   . SER B 2 380 ? -29.57970 38.69532  14.13097  1.000 168.28245 ? 415 SER F N   1 
ATOM   4471 C CA  . SER B 2 380 ? -30.06545 38.87901  12.76460  1.000 162.93356 ? 415 SER F CA  1 
ATOM   4472 C C   . SER B 2 380 ? -30.62668 40.29227  12.61620  1.000 166.54510 ? 415 SER F C   1 
ATOM   4473 O O   . SER B 2 380 ? -31.71948 40.58454  13.12214  1.000 171.59816 ? 415 SER F O   1 
ATOM   4474 C CB  . SER B 2 380 ? -31.12741 37.83598  12.41604  1.000 157.62661 ? 415 SER F CB  1 
ATOM   4475 O OG  . SER B 2 380 ? -30.60579 36.51872  12.47358  1.000 151.85370 ? 415 SER F OG  1 
ATOM   4476 N N   . CYS B 2 381 ? -29.87623 41.16871  11.93767  1.000 167.78832 ? 416 CYS F N   1 
ATOM   4477 C CA  . CYS B 2 381 ? -30.23078 42.57916  11.77983  1.000 174.69445 ? 416 CYS F CA  1 
ATOM   4478 C C   . CYS B 2 381 ? -30.58547 42.86392  10.32466  1.000 177.73563 ? 416 CYS F C   1 
ATOM   4479 O O   . CYS B 2 381 ? -29.77774 42.59816  9.43133   1.000 177.34788 ? 416 CYS F O   1 
ATOM   4480 C CB  . CYS B 2 381 ? -29.04913 43.46453  12.19947  1.000 176.90154 ? 416 CYS F CB  1 
ATOM   4481 S SG  . CYS B 2 381 ? -29.36205 45.17007  12.77476  1.000 186.35087 ? 416 CYS F SG  1 
ATOM   4482 N N   . TYR B 2 382 ? -31.77735 43.41695  10.08461  1.000 181.82194 ? 417 TYR F N   1 
ATOM   4483 C CA  . TYR B 2 382 ? -32.19942 43.73415  8.72303   1.000 181.30005 ? 417 TYR F CA  1 
ATOM   4484 C C   . TYR B 2 382 ? -33.03908 45.00616  8.69107   1.000 175.09185 ? 417 TYR F C   1 
ATOM   4485 O O   . TYR B 2 382 ? -33.73365 45.33941  9.65385   1.000 175.87283 ? 417 TYR F O   1 
ATOM   4486 C CB  . TYR B 2 382 ? -32.98261 42.57724  8.07532   1.000 181.63313 ? 417 TYR F CB  1 
ATOM   4487 C CG  . TYR B 2 382 ? -32.26017 41.24648  8.09397   1.000 180.53201 ? 417 TYR F CG  1 
ATOM   4488 C CD1 . TYR B 2 382 ? -31.19373 41.01378  7.23782   1.000 177.17652 ? 417 TYR F CD1 1 
ATOM   4489 C CD2 . TYR B 2 382 ? -32.62771 40.23289  8.96675   1.000 178.04518 ? 417 TYR F CD2 1 
ATOM   4490 C CE1 . TYR B 2 382 ? -30.51701 39.81843  7.24051   1.000 169.94291 ? 417 TYR F CE1 1 
ATOM   4491 C CE2 . TYR B 2 382 ? -31.94972 39.02242  8.97713   1.000 175.05456 ? 417 TYR F CE2 1 
ATOM   4492 C CZ  . TYR B 2 382 ? -30.89317 38.82602  8.10918   1.000 169.68577 ? 417 TYR F CZ  1 
ATOM   4493 O OH  . TYR B 2 382 ? -30.20408 37.63646  8.09669   1.000 168.16952 ? 417 TYR F OH  1 
ATOM   4494 N N   . GLY B 2 383 ? -32.95854 45.70971  7.56364   1.000 168.94111 ? 418 GLY F N   1 
ATOM   4495 C CA  . GLY B 2 383 ? -33.74513 46.91325  7.34620   1.000 160.58865 ? 418 GLY F CA  1 
ATOM   4496 C C   . GLY B 2 383 ? -33.22199 48.09810  8.13279   1.000 162.97393 ? 418 GLY F C   1 
ATOM   4497 O O   . GLY B 2 383 ? -32.01266 48.29960  8.29027   1.000 161.90174 ? 418 GLY F O   1 
ATOM   4498 N N   . LYS B 2 384 ? -34.16724 48.89443  8.63723   1.000 165.75797 ? 419 LYS F N   1 
ATOM   4499 C CA  . LYS B 2 384 ? -33.90061 50.07837  9.45551   1.000 172.06600 ? 419 LYS F CA  1 
ATOM   4500 C C   . LYS B 2 384 ? -34.00275 49.67344  10.92684  1.000 178.69667 ? 419 LYS F C   1 
ATOM   4501 O O   . LYS B 2 384 ? -35.05317 49.82100  11.55045  1.000 184.71999 ? 419 LYS F O   1 
ATOM   4502 C CB  . LYS B 2 384 ? -34.85674 51.21104  9.09475   1.000 169.73907 ? 419 LYS F CB  1 
ATOM   4503 C CG  . LYS B 2 384 ? -34.47043 51.95588  7.81472   1.000 168.79856 ? 419 LYS F CG  1 
ATOM   4504 C CD  . LYS B 2 384 ? -35.39349 53.14129  7.54611   1.000 164.10465 ? 419 LYS F CD  1 
ATOM   4505 C CE  . LYS B 2 384 ? -35.09629 53.77075  6.18843   1.000 161.11528 ? 419 LYS F CE  1 
ATOM   4506 N NZ  . LYS B 2 384 ? -33.73439 54.36452  6.12733   1.000 162.90860 ? 419 LYS F NZ  1 
ATOM   4507 N N   . THR B 2 385 ? -32.91700 49.13616  11.48404  1.000 177.33472 ? 420 THR F N   1 
ATOM   4508 C CA  . THR B 2 385 ? -32.92917 48.60869  12.84648  1.000 177.78216 ? 420 THR F CA  1 
ATOM   4509 C C   . THR B 2 385 ? -31.60178 48.92257  13.52601  1.000 182.52042 ? 420 THR F C   1 
ATOM   4510 O O   . THR B 2 385 ? -30.54082 48.81761  12.90345  1.000 179.24491 ? 420 THR F O   1 
ATOM   4511 C CB  . THR B 2 385 ? -33.20710 47.09811  12.86133  1.000 174.86764 ? 420 THR F CB  1 
ATOM   4512 O OG1 . THR B 2 385 ? -32.48463 46.46377  11.79769  1.000 176.92672 ? 420 THR F OG1 1 
ATOM   4513 C CG2 . THR B 2 385 ? -34.70254 46.82026  12.70982  1.000 162.08553 ? 420 THR F CG2 1 
ATOM   4514 N N   . LYS B 2 386 ? -31.66550 49.31265  14.80431  1.000 180.77005 ? 421 LYS F N   1 
ATOM   4515 C CA  . LYS B 2 386 ? -30.46627 49.65526  15.57644  1.000 176.67870 ? 421 LYS F CA  1 
ATOM   4516 C C   . LYS B 2 386 ? -29.93934 48.47540  16.39658  1.000 177.52498 ? 421 LYS F C   1 
ATOM   4517 O O   . LYS B 2 386 ? -30.43800 48.19278  17.49006  1.000 174.96006 ? 421 LYS F O   1 
ATOM   4518 C CB  . LYS B 2 386 ? -30.75110 50.83060  16.50856  1.000 167.79443 ? 421 LYS F CB  1 
ATOM   4519 C CG  . LYS B 2 386 ? -31.25425 52.10471  15.83980  1.000 161.41910 ? 421 LYS F CG  1 
ATOM   4520 C CD  . LYS B 2 386 ? -32.77719 52.15109  15.86052  1.000 147.34369 ? 421 LYS F CD  1 
ATOM   4521 C CE  . LYS B 2 386 ? -33.30984 52.13266  17.28564  1.000 130.60796 ? 421 LYS F CE  1 
ATOM   4522 N NZ  . LYS B 2 386 ? -34.79585 52.08346  17.35078  1.000 118.57921 ? 421 LYS F NZ  1 
ATOM   4523 N N   . CYS B 2 387 ? -28.93458 47.77876  15.86621  1.000 180.97699 ? 422 CYS F N   1 
ATOM   4524 C CA  . CYS B 2 387 ? -28.28350 46.66208  16.54570  1.000 173.96159 ? 422 CYS F CA  1 
ATOM   4525 C C   . CYS B 2 387 ? -26.92405 47.11249  17.07393  1.000 168.44248 ? 422 CYS F C   1 
ATOM   4526 O O   . CYS B 2 387 ? -26.15998 47.76557  16.35595  1.000 172.12338 ? 422 CYS F O   1 
ATOM   4527 C CB  . CYS B 2 387 ? -28.16247 45.43398  15.63864  1.000 168.09780 ? 422 CYS F CB  1 
ATOM   4528 S SG  . CYS B 2 387 ? -29.71254 45.03854  14.76747  1.000 195.93569 ? 422 CYS F SG  1 
ATOM   4529 N N   . THR B 2 388 ? -26.62722 46.75900  18.32650  1.000 165.20714 ? 423 THR F N   1 
ATOM   4530 C CA  . THR B 2 388 ? -25.42290 47.19153  19.02952  1.000 155.51553 ? 423 THR F CA  1 
ATOM   4531 C C   . THR B 2 388 ? -25.11290 46.17834  20.11729  1.000 160.77407 ? 423 THR F C   1 
ATOM   4532 O O   . THR B 2 388 ? -25.95055 45.34565  20.47872  1.000 164.17522 ? 423 THR F O   1 
ATOM   4533 C CB  . THR B 2 388 ? -25.54222 48.56417  19.72103  1.000 149.07461 ? 423 THR F CB  1 
ATOM   4534 O OG1 . THR B 2 388 ? -26.04790 48.37657  21.04960  1.000 161.37871 ? 423 THR F OG1 1 
ATOM   4535 C CG2 . THR B 2 388 ? -26.44763 49.53457  18.98065  1.000 140.92344 ? 423 THR F CG2 1 
ATOM   4536 N N   . ALA B 2 389 ? -23.88139 46.24250  20.62958  1.000 160.18926 ? 424 ALA F N   1 
ATOM   4537 C CA  . ALA B 2 389 ? -23.46162 45.39794  21.75504  1.000 165.13053 ? 424 ALA F CA  1 
ATOM   4538 C C   . ALA B 2 389 ? -22.72630 46.21405  22.81810  1.000 164.36347 ? 424 ALA F C   1 
ATOM   4539 O O   . ALA B 2 389 ? -21.49493 46.17576  22.87438  1.000 159.20488 ? 424 ALA F O   1 
ATOM   4540 C CB  . ALA B 2 389 ? -22.59061 44.25193  21.23856  1.000 164.10502 ? 424 ALA F CB  1 
ATOM   4541 N N   . SER B 2 390 ? -23.44562 46.96645  23.64998  1.000 162.60365 ? 425 SER F N   1 
ATOM   4542 C CA  . SER B 2 390 ? -22.67602 47.81360  24.54447  1.000 157.64991 ? 425 SER F CA  1 
ATOM   4543 C C   . SER B 2 390 ? -22.21913 46.98182  25.74128  1.000 163.40714 ? 425 SER F C   1 
ATOM   4544 O O   . SER B 2 390 ? -22.85657 46.00118  26.13879  1.000 163.48035 ? 425 SER F O   1 
ATOM   4545 C CB  . SER B 2 390 ? -23.51579 49.01091  24.99668  1.000 149.29750 ? 425 SER F CB  1 
ATOM   4546 O OG  . SER B 2 390 ? -22.77372 49.93437  25.77678  1.000 154.86961 ? 425 SER F OG  1 
ATOM   4547 N N   . ASN B 2 391 ? -21.08770 47.38901  26.31000  1.000 161.42233 ? 426 ASN F N   1 
ATOM   4548 C CA  . ASN B 2 391 ? -20.51750 46.88881  27.55948  1.000 157.07041 ? 426 ASN F CA  1 
ATOM   4549 C C   . ASN B 2 391 ? -20.57995 47.87802  28.73135  1.000 167.66447 ? 426 ASN F C   1 
ATOM   4550 O O   . ASN B 2 391 ? -20.58884 49.09459  28.54649  1.000 171.10611 ? 426 ASN F O   1 
ATOM   4551 C CB  . ASN B 2 391 ? -19.05916 46.44176  27.34501  1.000 154.69674 ? 426 ASN F CB  1 
ATOM   4552 C CG  . ASN B 2 391 ? -18.50666 45.72923  28.53858  1.000 157.58169 ? 426 ASN F CG  1 
ATOM   4553 O OD1 . ASN B 2 391 ? -18.35310 46.31888  29.59997  1.000 172.08215 ? 426 ASN F OD1 1 
ATOM   4554 N ND2 . ASN B 2 391 ? -18.26022 44.42261  28.39423  1.000 139.26056 ? 426 ASN F ND2 1 
ATOM   4555 N N   . LYS B 2 392 ? -20.76030 47.33318  29.94276  1.000 176.85079 ? 427 LYS F N   1 
ATOM   4556 C CA  . LYS B 2 392 ? -20.95279 48.17214  31.12652  1.000 178.80883 ? 427 LYS F CA  1 
ATOM   4557 C C   . LYS B 2 392 ? -19.73571 49.05457  31.36523  1.000 180.74336 ? 427 LYS F C   1 
ATOM   4558 O O   . LYS B 2 392 ? -19.86387 50.18705  31.84365  1.000 176.82060 ? 427 LYS F O   1 
ATOM   4559 C CB  . LYS B 2 392 ? -21.21905 47.38826  32.41102  1.000 163.75989 ? 427 LYS F CB  1 
ATOM   4560 C CG  . LYS B 2 392 ? -21.48006 48.36885  33.60149  1.000 144.98269 ? 427 LYS F CG  1 
ATOM   4561 C CD  . LYS B 2 392 ? -21.46277 47.75560  34.98385  1.000 130.29085 ? 427 LYS F CD  1 
ATOM   4562 C CE  . LYS B 2 392 ? -21.58016 48.82381  36.04969  1.000 120.06270 ? 427 LYS F CE  1 
ATOM   4563 N NZ  . LYS B 2 392 ? -20.54028 49.87467  35.96239  1.000 107.96649 ? 427 LYS F NZ  1 
ATOM   4564 N N   . ASN B 2 393 ? -18.53794 48.56373  31.00763  1.000 187.23108 ? 428 ASN F N   1 
ATOM   4565 C CA  . ASN B 2 393 ? -17.30418 49.25645  31.31926  1.000 185.57232 ? 428 ASN F CA  1 
ATOM   4566 C C   . ASN B 2 393 ? -16.72174 49.99896  30.13635  1.000 189.37055 ? 428 ASN F C   1 
ATOM   4567 O O   . ASN B 2 393 ? -15.89915 50.90389  30.33846  1.000 196.22101 ? 428 ASN F O   1 
ATOM   4568 C CB  . ASN B 2 393 ? -16.26266 48.20869  31.71254  1.000 186.51408 ? 428 ASN F CB  1 
ATOM   4569 C CG  . ASN B 2 393 ? -16.75513 47.26401  32.77266  1.000 189.04449 ? 428 ASN F CG  1 
ATOM   4570 O OD1 . ASN B 2 393 ? -17.75055 47.52261  33.45098  1.000 184.59480 ? 428 ASN F OD1 1 
ATOM   4571 N ND2 . ASN B 2 393 ? -16.09510 46.11878  32.87645  1.000 195.59296 ? 428 ASN F ND2 1 
ATOM   4572 N N   . ARG B 2 394 ? -17.08933 49.62240  28.91810  1.000 184.89491 ? 429 ARG F N   1 
ATOM   4573 C CA  . ARG B 2 394 ? -16.63560 50.31862  27.72632  1.000 183.53314 ? 429 ARG F CA  1 
ATOM   4574 C C   . ARG B 2 394 ? -17.83260 50.42674  26.80309  1.000 178.42807 ? 429 ARG F C   1 
ATOM   4575 O O   . ARG B 2 394 ? -18.76000 49.62328  26.87709  1.000 175.32873 ? 429 ARG F O   1 
ATOM   4576 C CB  . ARG B 2 394 ? -15.47654 49.59923  27.03371  1.000 186.80429 ? 429 ARG F CB  1 
ATOM   4577 C CG  . ARG B 2 394 ? -14.21980 49.53711  27.87008  1.000 194.12997 ? 429 ARG F CG  1 
ATOM   4578 C CD  . ARG B 2 394 ? -13.66230 50.92352  28.22194  1.000 197.10645 ? 429 ARG F CD  1 
ATOM   4579 N NE  . ARG B 2 394 ? -13.22186 51.70348  27.06818  1.000 203.09730 ? 429 ARG F NE  1 
ATOM   4580 C CZ  . ARG B 2 394 ? -11.97574 51.74491  26.61677  1.000 201.83427 ? 429 ARG F CZ  1 
ATOM   4581 N NH1 . ARG B 2 394 ? -11.00418 51.07662  27.21165  1.000 203.30142 ? 429 ARG F NH1 1 
ATOM   4582 N NH2 . ARG B 2 394 ? -11.69604 52.48281  25.54597  1.000 192.05643 ? 429 ARG F NH2 1 
ATOM   4583 N N   . GLY B 2 395 ? -17.84797 51.45161  25.96586  1.000 178.63368 ? 430 GLY F N   1 
ATOM   4584 C CA  . GLY B 2 395 ? -19.03234 51.56336  25.15948  1.000 172.39324 ? 430 GLY F CA  1 
ATOM   4585 C C   . GLY B 2 395 ? -19.20540 50.46066  24.12852  1.000 168.26775 ? 430 GLY F C   1 
ATOM   4586 O O   . GLY B 2 395 ? -18.69932 49.33821  24.24823  1.000 169.51598 ? 430 GLY F O   1 
ATOM   4587 N N   . ILE B 2 396 ? -19.93723 50.81963  23.08184  1.000 159.85811 ? 431 ILE F N   1 
ATOM   4588 C CA  . ILE B 2 396 ? -20.25815 49.95136  21.95465  1.000 153.16146 ? 431 ILE F CA  1 
ATOM   4589 C C   . ILE B 2 396 ? -18.96326 49.71908  21.17575  1.000 154.04773 ? 431 ILE F C   1 
ATOM   4590 O O   . ILE B 2 396 ? -18.30754 50.67014  20.72374  1.000 159.21911 ? 431 ILE F O   1 
ATOM   4591 C CB  . ILE B 2 396 ? -21.39086 50.51280  21.08185  1.000 152.86479 ? 431 ILE F CB  1 
ATOM   4592 C CG1 . ILE B 2 396 ? -22.65135 50.70218  21.95411  1.000 148.66758 ? 431 ILE F CG1 1 
ATOM   4593 C CG2 . ILE B 2 396 ? -21.69454 49.57490  19.92123  1.000 155.67860 ? 431 ILE F CG2 1 
ATOM   4594 C CD1 . ILE B 2 396 ? -23.07672 52.11321  22.16540  1.000 142.40755 ? 431 ILE F CD1 1 
ATOM   4595 N N   . ILE B 2 397 ? -18.57680 48.44999  21.01354  1.000 156.75302 ? 432 ILE F N   1 
ATOM   4596 C CA  . ILE B 2 397 ? -17.34023 48.10888  20.30225  1.000 159.64088 ? 432 ILE F CA  1 
ATOM   4597 C C   . ILE B 2 397 ? -17.63573 47.60953  18.90468  1.000 171.07342 ? 432 ILE F C   1 
ATOM   4598 O O   . ILE B 2 397 ? -16.72506 47.59270  18.06119  1.000 178.23727 ? 432 ILE F O   1 
ATOM   4599 C CB  . ILE B 2 397 ? -16.56987 46.97346  21.02844  1.000 151.77188 ? 432 ILE F CB  1 
ATOM   4600 C CG1 . ILE B 2 397 ? -16.67925 47.03701  22.55816  1.000 157.41091 ? 432 ILE F CG1 1 
ATOM   4601 C CG2 . ILE B 2 397 ? -15.11144 46.93774  20.60425  1.000 142.24916 ? 432 ILE F CG2 1 
ATOM   4602 C CD1 . ILE B 2 397 ? -15.84990 48.12077  23.21486  1.000 152.97726 ? 432 ILE F CD1 1 
ATOM   4603 N N   . LYS B 2 398 ? -18.88943 47.28330  18.61143  1.000 174.13363 ? 433 LYS F N   1 
ATOM   4604 C CA  . LYS B 2 398 ? -19.32600 46.88810  17.28311  1.000 167.65065 ? 433 LYS F CA  1 
ATOM   4605 C C   . LYS B 2 398 ? -20.80434 47.18667  17.11726  1.000 169.59700 ? 433 LYS F C   1 
ATOM   4606 O O   . LYS B 2 398 ? -21.63018 46.85712  17.97311  1.000 171.13969 ? 433 LYS F O   1 
ATOM   4607 C CB  . LYS B 2 398 ? -19.07122 45.40209  16.95506  1.000 155.31078 ? 433 LYS F CB  1 
ATOM   4608 C CG  . LYS B 2 398 ? -17.67479 44.87919  17.23805  1.000 154.75869 ? 433 LYS F CG  1 
ATOM   4609 C CD  . LYS B 2 398 ? -17.63172 44.02149  18.48897  1.000 153.14082 ? 433 LYS F CD  1 
ATOM   4610 C CE  . LYS B 2 398 ? -16.20586 43.56496  18.82549  1.000 139.10110 ? 433 LYS F CE  1 
ATOM   4611 N NZ  . LYS B 2 398 ? -16.10412 42.82548  20.12633  1.000 114.78720 ? 433 LYS F NZ  1 
ATOM   4612 N N   . THR B 2 399 ? -21.11142 47.80492  16.00000  1.000 167.03137 ? 434 THR F N   1 
ATOM   4613 C CA  . THR B 2 399 ? -22.46125 48.08481  15.56487  1.000 169.99130 ? 434 THR F CA  1 
ATOM   4614 C C   . THR B 2 399 ? -22.63390 47.12793  14.40532  1.000 174.32745 ? 434 THR F C   1 
ATOM   4615 O O   . THR B 2 399 ? -21.85455 47.15937  13.44855  1.000 173.34544 ? 434 THR F O   1 
ATOM   4616 C CB  . THR B 2 399 ? -22.64043 49.54224  15.15168  1.000 162.11834 ? 434 THR F CB  1 
ATOM   4617 O OG1 . THR B 2 399 ? -22.27004 50.39348  16.24405  1.000 147.81630 ? 434 THR F OG1 1 
ATOM   4618 C CG2 . THR B 2 399 ? -24.08927 49.79736  14.79207  1.000 157.98664 ? 434 THR F CG2 1 
ATOM   4619 N N   . PHE B 2 400 ? -23.64872 46.27984  14.49766  1.000 178.69026 ? 435 PHE F N   1 
ATOM   4620 C CA  . PHE B 2 400 ? -23.84537 45.24890  13.49857  1.000 180.10480 ? 435 PHE F CA  1 
ATOM   4621 C C   . PHE B 2 400 ? -24.45771 45.83476  12.24435  1.000 181.50377 ? 435 PHE F C   1 
ATOM   4622 O O   . PHE B 2 400 ? -25.31893 46.71812  12.29867  1.000 181.61793 ? 435 PHE F O   1 
ATOM   4623 C CB  . PHE B 2 400 ? -24.77120 44.15886  14.03702  1.000 175.64993 ? 435 PHE F CB  1 
ATOM   4624 C CG  . PHE B 2 400 ? -24.29025 43.50607  15.29864  1.000 157.35363 ? 435 PHE F CG  1 
ATOM   4625 C CD1 . PHE B 2 400 ? -23.38692 42.45747  15.26440  1.000 151.42697 ? 435 PHE F CD1 1 
ATOM   4626 C CD2 . PHE B 2 400 ? -24.77668 43.92675  16.52444  1.000 155.26772 ? 435 PHE F CD2 1 
ATOM   4627 C CE1 . PHE B 2 400 ? -22.96075 41.85939  16.43673  1.000 152.97164 ? 435 PHE F CE1 1 
ATOM   4628 C CE2 . PHE B 2 400 ? -24.35808 43.33448  17.69484  1.000 163.32173 ? 435 PHE F CE2 1 
ATOM   4629 C CZ  . PHE B 2 400 ? -23.44973 42.29970  17.65410  1.000 161.00272 ? 435 PHE F CZ  1 
ATOM   4630 N N   . SER B 2 401 ? -23.98697 45.33596  11.10636  1.000 176.81408 ? 436 SER F N   1 
ATOM   4631 C CA  . SER B 2 401 ? -24.55592 45.70079  9.82732   1.000 172.65473 ? 436 SER F CA  1 
ATOM   4632 C C   . SER B 2 401 ? -25.64572 44.70449  9.45350   1.000 171.29561 ? 436 SER F C   1 
ATOM   4633 O O   . SER B 2 401 ? -25.97302 43.77568  10.19485  1.000 169.36115 ? 436 SER F O   1 
ATOM   4634 C CB  . SER B 2 401 ? -23.46899 45.76619  8.75236   1.000 171.75503 ? 436 SER F CB  1 
ATOM   4635 O OG  . SER B 2 401 ? -22.77287 44.53524  8.64857   1.000 173.06632 ? 436 SER F OG  1 
ATOM   4636 N N   . ASN B 2 402 ? -26.20625 44.90621  8.27648   1.000 173.06848 ? 437 ASN F N   1 
ATOM   4637 C CA  . ASN B 2 402 ? -27.28397 44.06584  7.78801   1.000 174.36058 ? 437 ASN F CA  1 
ATOM   4638 C C   . ASN B 2 402 ? -26.78727 42.65008  7.48050   1.000 173.82424 ? 437 ASN F C   1 
ATOM   4639 O O   . ASN B 2 402 ? -25.78037 42.47085  6.78539   1.000 173.48040 ? 437 ASN F O   1 
ATOM   4640 C CB  . ASN B 2 402 ? -27.88349 44.72800  6.55262   1.000 174.82393 ? 437 ASN F CB  1 
ATOM   4641 C CG  . ASN B 2 402 ? -29.37914 44.53365  6.44710   1.000 178.15357 ? 437 ASN F CG  1 
ATOM   4642 O OD1 . ASN B 2 402 ? -29.87302 43.42756  6.28817   1.000 182.96753 ? 437 ASN F OD1 1 
ATOM   4643 N ND2 . ASN B 2 402 ? -30.11179 45.63969  6.51522   1.000 175.99338 ? 437 ASN F ND2 1 
ATOM   4644 N N   . GLY B 2 403 ? -27.49208 41.64198  8.01573   1.000 169.50329 ? 438 GLY F N   1 
ATOM   4645 C CA  . GLY B 2 403 ? -27.20178 40.22349  7.91606   1.000 162.22440 ? 438 GLY F CA  1 
ATOM   4646 C C   . GLY B 2 403 ? -27.24503 39.51014  9.25809   1.000 165.96920 ? 438 GLY F C   1 
ATOM   4647 O O   . GLY B 2 403 ? -27.73761 40.03922  10.26187  1.000 165.61639 ? 438 GLY F O   1 
ATOM   4648 N N   . CYS B 2 404 ? -26.72601 38.27657  9.26096   1.000 166.71983 ? 439 CYS F N   1 
ATOM   4649 C CA  . CYS B 2 404 ? -26.65752 37.39991  10.43155  1.000 167.70732 ? 439 CYS F CA  1 
ATOM   4650 C C   . CYS B 2 404 ? -25.23135 37.26008  10.94522  1.000 162.16262 ? 439 CYS F C   1 
ATOM   4651 O O   . CYS B 2 404 ? -24.31287 36.97120  10.16953  1.000 157.29635 ? 439 CYS F O   1 
ATOM   4652 C CB  . CYS B 2 404 ? -27.20087 36.00000  10.09614  1.000 169.94764 ? 439 CYS F CB  1 
ATOM   4653 S SG  . CYS B 2 404 ? -27.02225 34.71228  11.40519  1.000 156.78213 ? 439 CYS F SG  1 
ATOM   4654 N N   . ASP B 2 405 ? -25.04939 37.44749  12.25327  1.000 154.99861 ? 440 ASP F N   1 
ATOM   4655 C CA  . ASP B 2 405 ? -23.72606 37.35040  12.84850  1.000 148.71800 ? 440 ASP F CA  1 
ATOM   4656 C C   . ASP B 2 405 ? -23.83696 36.64774  14.19913  1.000 151.66576 ? 440 ASP F C   1 
ATOM   4657 O O   . ASP B 2 405 ? -24.93005 36.28778  14.65140  1.000 152.36075 ? 440 ASP F O   1 
ATOM   4658 C CB  . ASP B 2 405 ? -23.08382 38.73764  12.98454  1.000 142.59354 ? 440 ASP F CB  1 
ATOM   4659 C CG  . ASP B 2 405 ? -21.57180 38.68585  12.91304  1.000 142.82530 ? 440 ASP F CG  1 
ATOM   4660 O OD1 . ASP B 2 405 ? -21.01123 37.58503  13.10011  1.000 147.21435 ? 440 ASP F OD1 1 
ATOM   4661 O OD2 . ASP B 2 405 ? -20.94660 39.73792  12.65702  1.000 127.18317 ? 440 ASP F OD2 1 
ATOM   4662 N N   . TYR B 2 406 ? -22.69430 36.53561  14.87718  1.000 154.81704 ? 441 TYR F N   1 
ATOM   4663 C CA  . TYR B 2 406 ? -22.54950 35.84302  16.15146  1.000 152.42248 ? 441 TYR F CA  1 
ATOM   4664 C C   . TYR B 2 406 ? -21.42679 36.52131  16.91395  1.000 146.65107 ? 441 TYR F C   1 
ATOM   4665 O O   . TYR B 2 406 ? -20.47122 37.02351  16.31596  1.000 148.35775 ? 441 TYR F O   1 
ATOM   4666 C CB  . TYR B 2 406 ? -22.23122 34.34799  15.97257  1.000 147.67361 ? 441 TYR F CB  1 
ATOM   4667 C CG  . TYR B 2 406 ? -21.87798 33.58429  17.25018  1.000 147.98513 ? 441 TYR F CG  1 
ATOM   4668 C CD1 . TYR B 2 406 ? -22.86686 33.03177  18.06286  1.000 150.23403 ? 441 TYR F CD1 1 
ATOM   4669 C CD2 . TYR B 2 406 ? -20.54810 33.39499  17.62536  1.000 143.15984 ? 441 TYR F CD2 1 
ATOM   4670 C CE1 . TYR B 2 406 ? -22.54138 32.33007  19.22595  1.000 144.46227 ? 441 TYR F CE1 1 
ATOM   4671 C CE2 . TYR B 2 406 ? -20.21466 32.69633  18.78491  1.000 142.81831 ? 441 TYR F CE2 1 
ATOM   4672 C CZ  . TYR B 2 406 ? -21.21579 32.16590  19.57991  1.000 139.42964 ? 441 TYR F CZ  1 
ATOM   4673 O OH  . TYR B 2 406 ? -20.89991 31.47252  20.73043  1.000 117.76064 ? 441 TYR F OH  1 
ATOM   4674 N N   . VAL B 2 407 ? -21.52475 36.50215  18.23850  1.000 142.52707 ? 442 VAL F N   1 
ATOM   4675 C CA  . VAL B 2 407 ? -20.49303 37.09168  19.08099  1.000 138.43582 ? 442 VAL F CA  1 
ATOM   4676 C C   . VAL B 2 407 ? -20.25783 36.18169  20.27496  1.000 137.30074 ? 442 VAL F C   1 
ATOM   4677 O O   . VAL B 2 407 ? -21.20202 35.60165  20.82451  1.000 139.00741 ? 442 VAL F O   1 
ATOM   4678 C CB  . VAL B 2 407 ? -20.88691 38.51479  19.54510  1.000 127.89852 ? 442 VAL F CB  1 
ATOM   4679 C CG1 . VAL B 2 407 ? -19.87275 39.06177  20.52176  1.000 119.20131 ? 442 VAL F CG1 1 
ATOM   4680 C CG2 . VAL B 2 407 ? -21.02436 39.45743  18.36237  1.000 132.86890 ? 442 VAL F CG2 1 
ATOM   4681 N N   . SER B 2 408 ? -18.99364 36.05014  20.66471  1.000 133.31740 ? 443 SER F N   1 
ATOM   4682 C CA  . SER B 2 408 ? -18.63896 35.24938  21.81928  1.000 130.33256 ? 443 SER F CA  1 
ATOM   4683 C C   . SER B 2 408 ? -18.90735 36.05478  23.08776  1.000 134.97704 ? 443 SER F C   1 
ATOM   4684 O O   . SER B 2 408 ? -19.03022 37.28296  23.06072  1.000 129.66713 ? 443 SER F O   1 
ATOM   4685 C CB  . SER B 2 408 ? -17.17572 34.81019  21.75183  1.000 134.94148 ? 443 SER F CB  1 
ATOM   4686 O OG  . SER B 2 408 ? -16.79645 34.12666  22.93348  1.000 142.60341 ? 443 SER F OG  1 
ATOM   4687 N N   . ASN B 2 409 ? -18.98754 35.34929  24.21101  1.000 145.94129 ? 444 ASN F N   1 
ATOM   4688 C CA  . ASN B 2 409 ? -19.18032 36.00906  25.49474  1.000 140.58735 ? 444 ASN F CA  1 
ATOM   4689 C C   . ASN B 2 409 ? -17.88622 36.54228  26.09021  1.000 135.88218 ? 444 ASN F C   1 
ATOM   4690 O O   . ASN B 2 409 ? -17.93586 37.24439  27.10725  1.000 131.75671 ? 444 ASN F O   1 
ATOM   4691 C CB  . ASN B 2 409 ? -19.86126 35.05677  26.48264  1.000 136.63513 ? 444 ASN F CB  1 
ATOM   4692 C CG  . ASN B 2 409 ? -19.08651 33.77251  26.69189  1.000 142.39197 ? 444 ASN F CG  1 
ATOM   4693 O OD1 . ASN B 2 409 ? -18.04072 33.55180  26.08183  1.000 140.67084 ? 444 ASN F OD1 1 
ATOM   4694 N ND2 . ASN B 2 409 ? -19.60312 32.91445  27.55994  1.000 149.42389 ? 444 ASN F ND2 1 
ATOM   4695 N N   . LYS B 2 410 ? -16.73890 36.24200  25.48622  1.000 139.55631 ? 445 LYS F N   1 
ATOM   4696 C CA  . LYS B 2 410 ? -15.45221 36.70409  26.00392  1.000 141.92569 ? 445 LYS F CA  1 
ATOM   4697 C C   . LYS B 2 410 ? -15.29686 38.19522  25.72336  1.000 136.76791 ? 445 LYS F C   1 
ATOM   4698 O O   . LYS B 2 410 ? -14.95481 38.60318  24.61101  1.000 143.67363 ? 445 LYS F O   1 
ATOM   4699 C CB  . LYS B 2 410 ? -14.31997 35.92436  25.34530  1.000 150.93462 ? 445 LYS F CB  1 
ATOM   4700 C CG  . LYS B 2 410 ? -14.29086 34.43576  25.64115  1.000 144.03883 ? 445 LYS F CG  1 
ATOM   4701 C CD  . LYS B 2 410 ? -13.05040 33.81390  25.02208  1.000 142.31914 ? 445 LYS F CD  1 
ATOM   4702 C CE  . LYS B 2 410 ? -12.93335 32.34349  25.35213  1.000 140.17957 ? 445 LYS F CE  1 
ATOM   4703 N NZ  . LYS B 2 410 ? -14.05572 31.58900  24.71903  1.000 138.80210 ? 445 LYS F NZ  1 
ATOM   4704 N N   . GLY B 2 411 ? -15.54600 39.01639  26.74185  1.000 127.54589 ? 446 GLY F N   1 
ATOM   4705 C CA  . GLY B 2 411 ? -15.44471 40.45669  26.64397  1.000 128.49326 ? 446 GLY F CA  1 
ATOM   4706 C C   . GLY B 2 411 ? -16.73717 41.17956  26.33568  1.000 130.35853 ? 446 GLY F C   1 
ATOM   4707 O O   . GLY B 2 411 ? -16.76400 42.41533  26.38551  1.000 127.03351 ? 446 GLY F O   1 
ATOM   4708 N N   . VAL B 2 412 ? -17.80733 40.45971  26.02038  1.000 131.72930 ? 447 VAL F N   1 
ATOM   4709 C CA  . VAL B 2 412 ? -19.09012 41.06034  25.68028  1.000 129.81202 ? 447 VAL F CA  1 
ATOM   4710 C C   . VAL B 2 412 ? -20.03524 40.82780  26.84930  1.000 141.00744 ? 447 VAL F C   1 
ATOM   4711 O O   . VAL B 2 412 ? -20.11099 39.71051  27.37488  1.000 143.55210 ? 447 VAL F O   1 
ATOM   4712 C CB  . VAL B 2 412 ? -19.64408 40.48973  24.36762  1.000 119.38122 ? 447 VAL F CB  1 
ATOM   4713 C CG1 . VAL B 2 412 ? -21.01036 41.07547  24.08345  1.000 126.03753 ? 447 VAL F CG1 1 
ATOM   4714 C CG2 . VAL B 2 412 ? -18.67063 40.79025  23.24121  1.000 113.35170 ? 447 VAL F CG2 1 
ATOM   4715 N N   . ASP B 2 413 ? -20.75768 41.87116  27.25709  1.000 148.96147 ? 448 ASP F N   1 
ATOM   4716 C CA  . ASP B 2 413 ? -21.71901 41.74415  28.34654  1.000 151.14891 ? 448 ASP F CA  1 
ATOM   4717 C C   . ASP B 2 413 ? -23.17948 41.80654  27.92090  1.000 148.03286 ? 448 ASP F C   1 
ATOM   4718 O O   . ASP B 2 413 ? -23.97667 40.96859  28.35317  1.000 140.57947 ? 448 ASP F O   1 
ATOM   4719 C CB  . ASP B 2 413 ? -21.44207 42.83504  29.39040  1.000 146.37216 ? 448 ASP F CB  1 
ATOM   4720 C CG  . ASP B 2 413 ? -20.09914 42.65987  30.07000  1.000 143.80561 ? 448 ASP F CG  1 
ATOM   4721 O OD1 . ASP B 2 413 ? -19.29996 41.81887  29.60852  1.000 140.81965 ? 448 ASP F OD1 1 
ATOM   4722 O OD2 . ASP B 2 413 ? -19.83854 43.36584  31.06493  1.000 150.17133 ? 448 ASP F OD2 1 
ATOM   4723 N N   . THR B 2 414 ? -23.56207 42.76702  27.08168  1.000 146.19198 ? 449 THR F N   1 
ATOM   4724 C CA  . THR B 2 414 ? -24.94988 42.92125  26.66631  1.000 141.34539 ? 449 THR F CA  1 
ATOM   4725 C C   . THR B 2 414 ? -25.03567 43.07665  25.15560  1.000 145.86037 ? 449 THR F C   1 
ATOM   4726 O O   . THR B 2 414 ? -24.05982 43.43165  24.48919  1.000 144.34918 ? 449 THR F O   1 
ATOM   4727 C CB  . THR B 2 414 ? -25.61964 44.13105  27.33993  1.000 141.73642 ? 449 THR F CB  1 
ATOM   4728 O OG1 . THR B 2 414 ? -24.91238 45.32697  26.99165  1.000 146.63278 ? 449 THR F OG1 1 
ATOM   4729 C CG2 . THR B 2 414 ? -25.62999 43.97564  28.85547  1.000 143.79332 ? 449 THR F CG2 1 
ATOM   4730 N N   . VAL B 2 415 ? -26.22534 42.80718  24.61787  1.000 152.13836 ? 450 VAL F N   1 
ATOM   4731 C CA  . VAL B 2 415 ? -26.50628 42.99296  23.19774  1.000 151.60567 ? 450 VAL F CA  1 
ATOM   4732 C C   . VAL B 2 415 ? -27.82019 43.74773  23.06766  1.000 148.25582 ? 450 VAL F C   1 
ATOM   4733 O O   . VAL B 2 415 ? -28.84332 43.31162  23.59984  1.000 149.36441 ? 450 VAL F O   1 
ATOM   4734 C CB  . VAL B 2 415 ? -26.57251 41.65140  22.43855  1.000 144.70432 ? 450 VAL F CB  1 
ATOM   4735 C CG1 . VAL B 2 415 ? -27.20717 41.83961  21.06886  1.000 124.96852 ? 450 VAL F CG1 1 
ATOM   4736 C CG2 . VAL B 2 415 ? -25.18386 41.05719  22.28753  1.000 141.75537 ? 450 VAL F CG2 1 
ATOM   4737 N N   . SER B 2 416 ? -27.80904 44.85367  22.33385  1.000 148.66825 ? 451 SER F N   1 
ATOM   4738 C CA  . SER B 2 416 ? -28.99946 45.67684  22.17191  1.000 154.03159 ? 451 SER F CA  1 
ATOM   4739 C C   . SER B 2 416 ? -29.48131 45.56691  20.73187  1.000 156.11467 ? 451 SER F C   1 
ATOM   4740 O O   . SER B 2 416 ? -28.69588 45.74503  19.79549  1.000 163.50349 ? 451 SER F O   1 
ATOM   4741 C CB  . SER B 2 416 ? -28.71273 47.13574  22.53898  1.000 152.55209 ? 451 SER F CB  1 
ATOM   4742 O OG  . SER B 2 416 ? -29.88680 47.92522  22.45919  1.000 151.70137 ? 451 SER F OG  1 
ATOM   4743 N N   . VAL B 2 417 ? -30.77130 45.27169  20.56337  1.000 155.21368 ? 452 VAL F N   1 
ATOM   4744 C CA  . VAL B 2 417 ? -31.42727 45.19966  19.26275  1.000 161.34464 ? 452 VAL F CA  1 
ATOM   4745 C C   . VAL B 2 417 ? -32.66931 46.08555  19.32284  1.000 163.09600 ? 452 VAL F C   1 
ATOM   4746 O O   . VAL B 2 417 ? -33.64780 45.75318  20.00860  1.000 165.22092 ? 452 VAL F O   1 
ATOM   4747 C CB  . VAL B 2 417 ? -31.80759 43.75442  18.89614  1.000 158.89062 ? 452 VAL F CB  1 
ATOM   4748 C CG1 . VAL B 2 417 ? -32.65524 43.71463  17.63024  1.000 157.91268 ? 452 VAL F CG1 1 
ATOM   4749 C CG2 . VAL B 2 417 ? -30.56325 42.87581  18.76209  1.000 152.99183 ? 452 VAL F CG2 1 
ATOM   4750 N N   . GLY B 2 418 ? -32.61349 47.22624  18.63912  1.000 164.78102 ? 453 GLY F N   1 
ATOM   4751 C CA  . GLY B 2 418 ? -33.70059 48.19481  18.69860  1.000 153.52159 ? 453 GLY F CA  1 
ATOM   4752 C C   . GLY B 2 418 ? -33.80956 48.75382  20.10013  1.000 152.97706 ? 453 GLY F C   1 
ATOM   4753 O O   . GLY B 2 418 ? -32.82577 49.19993  20.70064  1.000 150.61880 ? 453 GLY F O   1 
ATOM   4754 N N   . ASN B 2 419 ? -35.02893 48.72618  20.63442  1.000 157.08333 ? 454 ASN F N   1 
ATOM   4755 C CA  . ASN B 2 419 ? -35.29993 49.14759  21.99901  1.000 158.55528 ? 454 ASN F CA  1 
ATOM   4756 C C   . ASN B 2 419 ? -35.33378 47.95407  22.95797  1.000 161.70906 ? 454 ASN F C   1 
ATOM   4757 O O   . ASN B 2 419 ? -35.83254 48.08057  24.08145  1.000 149.01311 ? 454 ASN F O   1 
ATOM   4758 C CB  . ASN B 2 419 ? -36.60061 49.95478  22.05767  1.000 143.91674 ? 454 ASN F CB  1 
ATOM   4759 C CG  . ASN B 2 419 ? -37.74260 49.27573  21.33388  1.000 146.01733 ? 454 ASN F CG  1 
ATOM   4760 O OD1 . ASN B 2 419 ? -37.52579 48.50017  20.40361  1.000 150.12378 ? 454 ASN F OD1 1 
ATOM   4761 N ND2 . ASN B 2 419 ? -38.96846 49.56958  21.75115  1.000 139.86738 ? 454 ASN F ND2 1 
ATOM   4762 N N   . THR B 2 420 ? -34.80271 46.80223  22.53556  1.000 171.74685 ? 455 THR F N   1 
ATOM   4763 C CA  . THR B 2 420 ? -34.79309 45.57656  23.33185  1.000 165.06899 ? 455 THR F CA  1 
ATOM   4764 C C   . THR B 2 420 ? -33.35354 45.22962  23.70027  1.000 157.90482 ? 455 THR F C   1 
ATOM   4765 O O   . THR B 2 420 ? -32.46235 45.30327  22.85263  1.000 161.87193 ? 455 THR F O   1 
ATOM   4766 C CB  . THR B 2 420 ? -35.45343 44.41669  22.57206  1.000 168.86025 ? 455 THR F CB  1 
ATOM   4767 O OG1 . THR B 2 420 ? -34.48493 43.75291  21.75009  1.000 167.11112 ? 455 THR F OG1 1 
ATOM   4768 C CG2 . THR B 2 420 ? -36.60123 44.91992  21.69265  1.000 158.53781 ? 455 THR F CG2 1 
ATOM   4769 N N   . LEU B 2 421 ? -33.10604 44.90342  24.96752  1.000 147.95344 ? 456 LEU F N   1 
ATOM   4770 C CA  . LEU B 2 421 ? -31.75921 44.55157  25.41071  1.000 147.03874 ? 456 LEU F CA  1 
ATOM   4771 C C   . LEU B 2 421 ? -31.70243 43.12199  25.93419  1.000 147.52542 ? 456 LEU F C   1 
ATOM   4772 O O   . LEU B 2 421 ? -32.44298 42.76907  26.85837  1.000 150.16272 ? 456 LEU F O   1 
ATOM   4773 C CB  . LEU B 2 421 ? -31.27242 45.52466  26.48803  1.000 144.68210 ? 456 LEU F CB  1 
ATOM   4774 C CG  . LEU B 2 421 ? -29.83980 45.31718  26.98845  1.000 138.74921 ? 456 LEU F CG  1 
ATOM   4775 C CD1 . LEU B 2 421 ? -28.82592 45.70612  25.92336  1.000 138.52571 ? 456 LEU F CD1 1 
ATOM   4776 C CD2 . LEU B 2 421 ? -29.60976 46.10927  28.26362  1.000 128.63537 ? 456 LEU F CD2 1 
ATOM   4777 N N   . TYR B 2 422 ? -30.83283 42.30035  25.34019  1.000 144.87297 ? 457 TYR F N   1 
ATOM   4778 C CA  . TYR B 2 422 ? -30.61709 40.93619  25.79350  1.000 144.68309 ? 457 TYR F CA  1 
ATOM   4779 C C   . TYR B 2 422 ? -29.31216 40.87711  26.58199  1.000 142.75016 ? 457 TYR F C   1 
ATOM   4780 O O   . TYR B 2 422 ? -28.38038 41.65752  26.34461  1.000 139.14873 ? 457 TYR F O   1 
ATOM   4781 C CB  . TYR B 2 422 ? -30.52670 39.94612  24.62481  1.000 144.84433 ? 457 TYR F CB  1 
ATOM   4782 C CG  . TYR B 2 422 ? -31.65789 39.94872  23.61861  1.000 148.57246 ? 457 TYR F CG  1 
ATOM   4783 C CD1 . TYR B 2 422 ? -32.75507 39.10702  23.77426  1.000 153.09282 ? 457 TYR F CD1 1 
ATOM   4784 C CD2 . TYR B 2 422 ? -31.61526 40.76846  22.49826  1.000 148.59616 ? 457 TYR F CD2 1 
ATOM   4785 C CE1 . TYR B 2 422 ? -33.78428 39.09395  22.84824  1.000 152.64991 ? 457 TYR F CE1 1 
ATOM   4786 C CE2 . TYR B 2 422 ? -32.64147 40.76739  21.57181  1.000 150.46522 ? 457 TYR F CE2 1 
ATOM   4787 C CZ  . TYR B 2 422 ? -33.72093 39.92732  21.74879  1.000 150.81908 ? 457 TYR F CZ  1 
ATOM   4788 O OH  . TYR B 2 422 ? -34.73980 39.92475  20.82300  1.000 153.38990 ? 457 TYR F OH  1 
ATOM   4789 N N   . CYS B 2 423 ? -29.23749 39.90437  27.48824  1.000 145.01545 ? 458 CYS F N   1 
ATOM   4790 C CA  . CYS B 2 423 ? -28.04569 39.62778  28.28206  1.000 145.42851 ? 458 CYS F CA  1 
ATOM   4791 C C   . CYS B 2 423 ? -27.33658 38.37280  27.78639  1.000 137.11084 ? 458 CYS F C   1 
ATOM   4792 O O   . CYS B 2 423 ? -27.98053 37.34838  27.53524  1.000 141.56298 ? 458 CYS F O   1 
ATOM   4793 C CB  . CYS B 2 423 ? -28.39703 39.48606  29.76892  1.000 148.31880 ? 458 CYS F CB  1 
ATOM   4794 S SG  . CYS B 2 423 ? -28.96779 41.02802  30.60178  1.000 166.61777 ? 458 CYS F SG  1 
ATOM   4795 N N   . VAL B 2 424 ? -26.01932 38.45055  27.65747  1.000 128.09319 ? 459 VAL F N   1 
ATOM   4796 C CA  . VAL B 2 424 ? -25.21969 37.33092  27.17682  1.000 125.65920 ? 459 VAL F CA  1 
ATOM   4797 C C   . VAL B 2 424 ? -24.79701 36.50502  28.38364  1.000 130.93444 ? 459 VAL F C   1 
ATOM   4798 O O   . VAL B 2 424 ? -24.37405 37.06300  29.40320  1.000 127.16954 ? 459 VAL F O   1 
ATOM   4799 C CB  . VAL B 2 424 ? -23.99590 37.82737  26.39542  1.000 121.48254 ? 459 VAL F CB  1 
ATOM   4800 C CG1 . VAL B 2 424 ? -23.23543 36.64963  25.81225  1.000 120.95661 ? 459 VAL F CG1 1 
ATOM   4801 C CG2 . VAL B 2 424 ? -24.42378 38.81045  25.32229  1.000 132.74924 ? 459 VAL F CG2 1 
ATOM   4802 N N   . ASN B 2 425 ? -24.91428 35.18073  28.28572  1.000 133.06096 ? 460 ASN F N   1 
ATOM   4803 C CA  . ASN B 2 425 ? -24.48978 34.34449  29.40082  1.000 133.01057 ? 460 ASN F CA  1 
ATOM   4804 C C   . ASN B 2 425 ? -22.97573 34.40913  29.54657  1.000 134.11545 ? 460 ASN F C   1 
ATOM   4805 O O   . ASN B 2 425 ? -22.24090 34.19382  28.57742  1.000 139.43724 ? 460 ASN F O   1 
ATOM   4806 C CB  . ASN B 2 425 ? -24.94668 32.90319  29.16959  1.000 128.98911 ? 460 ASN F CB  1 
ATOM   4807 C CG  . ASN B 2 425 ? -24.60585 31.98609  30.32593  1.000 127.64749 ? 460 ASN F CG  1 
ATOM   4808 O OD1 . ASN B 2 425 ? -24.37672 32.43769  31.44601  1.000 136.04459 ? 460 ASN F OD1 1 
ATOM   4809 N ND2 . ASN B 2 425 ? -24.57826 30.68409  30.05868  1.000 118.49101 ? 460 ASN F ND2 1 
ATOM   4810 N N   . LYS B 2 426 ? -22.50928 34.70289  30.76741  1.000 122.69971 ? 461 LYS F N   1 
ATOM   4811 C CA  . LYS B 2 426 ? -21.08494 34.86587  31.04303  1.000 127.02163 ? 461 LYS F CA  1 
ATOM   4812 C C   . LYS B 2 426 ? -20.38884 33.58334  31.49464  1.000 127.88938 ? 461 LYS F C   1 
ATOM   4813 O O   . LYS B 2 426 ? -19.38918 33.66919  32.22127  1.000 125.13731 ? 461 LYS F O   1 
ATOM   4814 C CB  . LYS B 2 426 ? -20.88865 35.95924  32.09541  1.000 121.49750 ? 461 LYS F CB  1 
ATOM   4815 C CG  . LYS B 2 426 ? -21.53395 37.29229  31.75315  1.000 123.36262 ? 461 LYS F CG  1 
ATOM   4816 C CD  . LYS B 2 426 ? -21.07128 37.81089  30.40318  1.000 129.69625 ? 461 LYS F CD  1 
ATOM   4817 C CE  . LYS B 2 426 ? -19.57869 38.11212  30.42550  1.000 129.64597 ? 461 LYS F CE  1 
ATOM   4818 N NZ  . LYS B 2 426 ? -19.07198 38.58228  29.10758  1.000 133.92061 ? 461 LYS F NZ  1 
ATOM   4819 N N   . GLN B 2 427 ? -20.85168 32.40293  31.09127  1.000 129.08517 ? 462 GLN F N   1 
ATOM   4820 C CA  . GLN B 2 427 ? -20.16357 31.18930  31.51729  1.000 134.64479 ? 462 GLN F CA  1 
ATOM   4821 C C   . GLN B 2 427 ? -18.86592 31.07886  30.71627  1.000 143.86331 ? 462 GLN F C   1 
ATOM   4822 O O   . GLN B 2 427 ? -18.82968 31.40500  29.52795  1.000 157.65536 ? 462 GLN F O   1 
ATOM   4823 C CB  . GLN B 2 427 ? -21.06750 29.95802  31.36861  1.000 132.32970 ? 462 GLN F CB  1 
ATOM   4824 C CG  . GLN B 2 427 ? -20.44372 28.62271  31.80718  1.000 139.39118 ? 462 GLN F CG  1 
ATOM   4825 C CD  . GLN B 2 427 ? -19.60504 27.93004  30.76664  1.000 150.85977 ? 462 GLN F CD  1 
ATOM   4826 O OE1 . GLN B 2 427 ? -19.76577 28.14673  29.56902  1.000 159.03158 ? 462 GLN F OE1 1 
ATOM   4827 N NE2 . GLN B 2 427 ? -18.68901 27.08137  31.22490  1.000 155.95245 ? 462 GLN F NE2 1 
ATOM   4828 N N   . GLU B 2 428 ? -17.79367 30.63291  31.36416  1.000 141.73871 ? 463 GLU F N   1 
ATOM   4829 C CA  . GLU B 2 428 ? -16.50059 30.51149  30.69460  1.000 152.64147 ? 463 GLU F CA  1 
ATOM   4830 C C   . GLU B 2 428 ? -16.42047 29.26575  29.81457  1.000 161.11204 ? 463 GLU F C   1 
ATOM   4831 O O   . GLU B 2 428 ? -16.81968 28.17093  30.21858  1.000 164.47389 ? 463 GLU F O   1 
ATOM   4832 C CB  . GLU B 2 428 ? -15.36863 30.51047  31.72338  1.000 160.53110 ? 463 GLU F CB  1 
ATOM   4833 C CG  . GLU B 2 428 ? -15.28393 31.79394  32.54537  1.000 168.91534 ? 463 GLU F CG  1 
ATOM   4834 C CD  . GLU B 2 428 ? -14.96758 33.01602  31.69485  1.000 177.07509 ? 463 GLU F CD  1 
ATOM   4835 O OE1 . GLU B 2 428 ? -14.27705 32.86343  30.66381  1.000 182.50871 ? 463 GLU F OE1 1 
ATOM   4836 O OE2 . GLU B 2 428 ? -15.41059 34.12878  32.05679  1.000 170.92164 ? 463 GLU F OE2 1 
ATOM   4837 N N   . GLY B 2 429 ? -15.84390 29.43763  28.62713  1.000 161.14497 ? 464 GLY F N   1 
ATOM   4838 C CA  . GLY B 2 429 ? -15.71219 28.36562  27.65443  1.000 148.90464 ? 464 GLY F CA  1 
ATOM   4839 C C   . GLY B 2 429 ? -15.14428 28.90889  26.36163  1.000 144.43241 ? 464 GLY F C   1 
ATOM   4840 O O   . GLY B 2 429 ? -14.97425 30.11780  26.18577  1.000 147.35769 ? 464 GLY F O   1 
ATOM   4841 N N   . GLN B 2 430 ? -14.86816 27.99213  25.43717  1.000 145.30683 ? 465 GLN F N   1 
ATOM   4842 C CA  . GLN B 2 430 ? -14.25067 28.33575  24.16074  1.000 145.84502 ? 465 GLN F CA  1 
ATOM   4843 C C   . GLN B 2 430 ? -15.23229 28.26251  23.00015  1.000 138.67599 ? 465 GLN F C   1 
ATOM   4844 O O   . GLN B 2 430 ? -15.93751 27.26244  22.82960  1.000 132.48789 ? 465 GLN F O   1 
ATOM   4845 C CB  . GLN B 2 430 ? -13.06060 27.41544  23.86555  1.000 146.54688 ? 465 GLN F CB  1 
ATOM   4846 C CG  . GLN B 2 430 ? -12.02115 27.31121  24.97872  1.000 149.85419 ? 465 GLN F CG  1 
ATOM   4847 C CD  . GLN B 2 430 ? -12.15632 26.03056  25.78513  1.000 150.74749 ? 465 GLN F CD  1 
ATOM   4848 O OE1 . GLN B 2 430 ? -13.10413 25.27184  25.60318  1.000 143.35164 ? 465 GLN F OE1 1 
ATOM   4849 N NE2 . GLN B 2 430 ? -11.19411 25.77447  26.66463  1.000 147.40112 ? 465 GLN F NE2 1 
ATOM   4850 N N   . SER B 2 431 ? -15.27386 29.33771  22.21688  1.000 134.90468 ? 466 SER F N   1 
ATOM   4851 C CA  . SER B 2 431 ? -16.07072 29.43007  21.00469  1.000 131.50369 ? 466 SER F CA  1 
ATOM   4852 C C   . SER B 2 431 ? -15.16436 29.26019  19.78896  1.000 136.51369 ? 466 SER F C   1 
ATOM   4853 O O   . SER B 2 431 ? -13.99426 29.65201  19.80000  1.000 135.64154 ? 466 SER F O   1 
ATOM   4854 C CB  . SER B 2 431 ? -16.81308 30.76696  20.92669  1.000 121.23655 ? 466 SER F CB  1 
ATOM   4855 O OG  . SER B 2 431 ? -17.70526 30.92336  22.01680  1.000 126.65174 ? 466 SER F OG  1 
ATOM   4856 N N   . LEU B 2 432 ? -15.72205 28.66401  18.73849  1.000 139.99672 ? 467 LEU F N   1 
ATOM   4857 C CA  . LEU B 2 432 ? -15.02058 28.40859  17.48464  1.000 135.26163 ? 467 LEU F CA  1 
ATOM   4858 C C   . LEU B 2 432 ? -15.89892 28.93016  16.36246  1.000 137.07962 ? 467 LEU F C   1 
ATOM   4859 O O   . LEU B 2 432 ? -17.04091 28.48471  16.21021  1.000 136.14733 ? 467 LEU F O   1 
ATOM   4860 C CB  . LEU B 2 432 ? -14.71646 26.91823  17.29019  1.000 131.33482 ? 467 LEU F CB  1 
ATOM   4861 C CG  . LEU B 2 432 ? -13.96078 26.55625  16.00665  1.000 130.89188 ? 467 LEU F CG  1 
ATOM   4862 C CD1 . LEU B 2 432 ? -12.64162 27.30756  15.93594  1.000 126.78195 ? 467 LEU F CD1 1 
ATOM   4863 C CD2 . LEU B 2 432 ? -13.71941 25.05656  15.91587  1.000 133.85069 ? 467 LEU F CD2 1 
ATOM   4864 N N   . TYR B 2 433 ? -15.37372 29.86910  15.58211  1.000 139.70657 ? 468 TYR F N   1 
ATOM   4865 C CA  . TYR B 2 433 ? -16.12743 30.45456  14.48163  1.000 135.55286 ? 468 TYR F CA  1 
ATOM   4866 C C   . TYR B 2 433 ? -15.80484 29.64698  13.22459  1.000 140.41047 ? 468 TYR F C   1 
ATOM   4867 O O   . TYR B 2 433 ? -14.69775 29.73342  12.68290  1.000 143.86216 ? 468 TYR F O   1 
ATOM   4868 C CB  . TYR B 2 433 ? -15.76745 31.93124  14.32408  1.000 121.44082 ? 468 TYR F CB  1 
ATOM   4869 C CG  . TYR B 2 433 ? -16.77621 32.74509  13.54486  1.000 122.91061 ? 468 TYR F CG  1 
ATOM   4870 C CD1 . TYR B 2 433 ? -16.89050 32.63692  12.16936  1.000 133.38871 ? 468 TYR F CD1 1 
ATOM   4871 C CD2 . TYR B 2 433 ? -17.60451 33.64813  14.19962  1.000 125.06000 ? 468 TYR F CD2 1 
ATOM   4872 C CE1 . TYR B 2 433 ? -17.81729 33.39072  11.46814  1.000 140.01256 ? 468 TYR F CE1 1 
ATOM   4873 C CE2 . TYR B 2 433 ? -18.53020 34.40614  13.51014  1.000 128.45092 ? 468 TYR F CE2 1 
ATOM   4874 C CZ  . TYR B 2 433 ? -18.63339 34.27548  12.14564  1.000 133.82038 ? 468 TYR F CZ  1 
ATOM   4875 O OH  . TYR B 2 433 ? -19.55721 35.03036  11.45869  1.000 132.30464 ? 468 TYR F OH  1 
ATOM   4876 N N   . VAL B 2 434 ? -16.78498 28.86932  12.76522  1.000 144.02448 ? 469 VAL F N   1 
ATOM   4877 C CA  . VAL B 2 434 ? -16.66468 28.00692  11.59012  1.000 145.67752 ? 469 VAL F CA  1 
ATOM   4878 C C   . VAL B 2 434 ? -17.14367 28.83131  10.39970  1.000 146.82137 ? 469 VAL F C   1 
ATOM   4879 O O   . VAL B 2 434 ? -18.34371 28.98109  10.16723  1.000 147.05533 ? 469 VAL F O   1 
ATOM   4880 C CB  . VAL B 2 434 ? -17.46038 26.70817  11.75282  1.000 141.03677 ? 469 VAL F CB  1 
ATOM   4881 C CG1 . VAL B 2 434 ? -17.33682 25.83294  10.51510  1.000 127.44965 ? 469 VAL F CG1 1 
ATOM   4882 C CG2 . VAL B 2 434 ? -16.99117 25.94192  12.98553  1.000 134.25643 ? 469 VAL F CG2 1 
ATOM   4883 N N   . LYS B 2 435 ? -16.19206 29.37582  9.64892   1.000 145.39071 ? 470 LYS F N   1 
ATOM   4884 C CA  . LYS B 2 435 ? -16.50993 30.23847  8.52312   1.000 145.14599 ? 470 LYS F CA  1 
ATOM   4885 C C   . LYS B 2 435 ? -17.16543 29.50434  7.35936   1.000 146.44499 ? 470 LYS F C   1 
ATOM   4886 O O   . LYS B 2 435 ? -16.91523 28.32348  7.10152   1.000 146.04526 ? 470 LYS F O   1 
ATOM   4887 C CB  . LYS B 2 435 ? -15.23319 30.86311  7.95125   1.000 133.60697 ? 470 LYS F CB  1 
ATOM   4888 C CG  . LYS B 2 435 ? -14.74669 32.17746  8.51308   1.000 125.71792 ? 470 LYS F CG  1 
ATOM   4889 C CD  . LYS B 2 435 ? -14.31994 32.03172  9.94935   1.000 133.84998 ? 470 LYS F CD  1 
ATOM   4890 C CE  . LYS B 2 435 ? -13.99575 33.38276  10.56017  1.000 135.42253 ? 470 LYS F CE  1 
ATOM   4891 N NZ  . LYS B 2 435 ? -13.59505 33.29017  11.99451  1.000 131.04317 ? 470 LYS F NZ  1 
ATOM   4892 N N   . GLY B 2 436 ? -18.02769 30.23466  6.66331   1.000 142.05696 ? 471 GLY F N   1 
ATOM   4893 C CA  . GLY B 2 436 ? -18.72443 29.75555  5.49140   1.000 144.50238 ? 471 GLY F CA  1 
ATOM   4894 C C   . GLY B 2 436 ? -19.66367 30.83400  5.00084   1.000 152.62493 ? 471 GLY F C   1 
ATOM   4895 O O   . GLY B 2 436 ? -20.15991 31.64169  5.78557   1.000 157.83734 ? 471 GLY F O   1 
ATOM   4896 N N   . GLU B 2 437 ? -19.91017 30.84992  3.70981   1.000 154.85606 ? 472 GLU F N   1 
ATOM   4897 C CA  . GLU B 2 437 ? -20.80508 31.83535  3.10575   1.000 156.95185 ? 472 GLU F CA  1 
ATOM   4898 C C   . GLU B 2 437 ? -22.27721 31.63395  3.45405   1.000 150.41774 ? 472 GLU F C   1 
ATOM   4899 O O   . GLU B 2 437 ? -22.78215 30.50878  3.34830   1.000 145.66122 ? 472 GLU F O   1 
ATOM   4900 C CB  . GLU B 2 437 ? -20.58583 31.96160  1.62559   1.000 167.07105 ? 472 GLU F CB  1 
ATOM   4901 C CG  . GLU B 2 437 ? -20.96839 33.37184  1.29445   1.000 170.05583 ? 472 GLU F CG  1 
ATOM   4902 C CD  . GLU B 2 437 ? -19.80834 34.32149  1.54079   1.000 171.60448 ? 472 GLU F CD  1 
ATOM   4903 O OE1 . GLU B 2 437 ? -18.64495 33.86269  1.50126   1.000 165.50147 ? 472 GLU F OE1 1 
ATOM   4904 O OE2 . GLU B 2 437 ? -20.05960 35.52705  1.76639   1.000 166.34157 ? 472 GLU F OE2 1 
ATOM   4905 N N   . PRO B 2 438 ? -22.99327 32.67937  3.87480   1.000 150.58433 ? 473 PRO F N   1 
ATOM   4906 C CA  . PRO B 2 438 ? -24.42855 32.51471  4.13503   1.000 151.54788 ? 473 PRO F CA  1 
ATOM   4907 C C   . PRO B 2 438 ? -25.16110 32.05629  2.88024   1.000 148.08215 ? 473 PRO F C   1 
ATOM   4908 O O   . PRO B 2 438 ? -25.06119 32.66538  1.81158   1.000 147.16314 ? 473 PRO F O   1 
ATOM   4909 C CB  . PRO B 2 438 ? -24.87612 33.91924  4.55863   1.000 147.66416 ? 473 PRO F CB  1 
ATOM   4910 C CG  . PRO B 2 438 ? -23.63999 34.58335  5.04305   1.000 154.02360 ? 473 PRO F CG  1 
ATOM   4911 C CD  . PRO B 2 438 ? -22.53872 34.04806  4.18227   1.000 149.30522 ? 473 PRO F CD  1 
ATOM   4912 N N   . ILE B 2 439 ? -25.90794 30.96053  3.04252   1.000 152.32459 ? 474 ILE F N   1 
ATOM   4913 C CA  . ILE B 2 439 ? -26.60461 30.25301  1.97217   1.000 150.15147 ? 474 ILE F CA  1 
ATOM   4914 C C   . ILE B 2 439 ? -27.72234 31.05003  1.31971   1.000 150.61418 ? 474 ILE F C   1 
ATOM   4915 O O   . ILE B 2 439 ? -28.14468 30.69977  0.20817   1.000 160.26231 ? 474 ILE F O   1 
ATOM   4916 C CB  . ILE B 2 439 ? -27.15925 28.91920  2.51413   1.000 151.79930 ? 474 ILE F CB  1 
ATOM   4917 C CG1 . ILE B 2 439 ? -28.29116 29.18172  3.51105   1.000 151.38113 ? 474 ILE F CG1 1 
ATOM   4918 C CG2 . ILE B 2 439 ? -26.04300 28.06262  3.10341   1.000 143.85915 ? 474 ILE F CG2 1 
ATOM   4919 C CD1 . ILE B 2 439 ? -28.93856 27.93125  4.05291   1.000 145.59441 ? 474 ILE F CD1 1 
ATOM   4920 N N   . ILE B 2 440 ? -28.15064 32.16166  1.92363   1.000 142.91638 ? 475 ILE F N   1 
ATOM   4921 C CA  . ILE B 2 440 ? -29.20861 32.95705  1.31466   1.000 148.43968 ? 475 ILE F CA  1 
ATOM   4922 C C   . ILE B 2 440 ? -28.75152 33.58566  0.01121   1.000 164.90872 ? 475 ILE F C   1 
ATOM   4923 O O   . ILE B 2 440 ? -29.59211 33.95173  -0.82089  1.000 163.71972 ? 475 ILE F O   1 
ATOM   4924 C CB  . ILE B 2 440 ? -29.69023 34.04778  2.29087   1.000 151.13675 ? 475 ILE F CB  1 
ATOM   4925 C CG1 . ILE B 2 440 ? -31.00545 34.66285  1.80621   1.000 149.74983 ? 475 ILE F CG1 1 
ATOM   4926 C CG2 . ILE B 2 440 ? -28.61245 35.11352  2.48755   1.000 148.40826 ? 475 ILE F CG2 1 
ATOM   4927 C CD1 . ILE B 2 440 ? -32.14030 33.67791  1.71658   1.000 148.17051 ? 475 ILE F CD1 1 
ATOM   4928 N N   . ASN B 2 441 ? -27.44171 33.72445  -0.19636  1.000 175.63548 ? 476 ASN F N   1 
ATOM   4929 C CA  . ASN B 2 441 ? -26.98191 34.28677  -1.45208  1.000 170.97400 ? 476 ASN F CA  1 
ATOM   4930 C C   . ASN B 2 441 ? -27.07496 33.29437  -2.60999  1.000 167.39002 ? 476 ASN F C   1 
ATOM   4931 O O   . ASN B 2 441 ? -26.93158 33.71219  -3.76232  1.000 176.45356 ? 476 ASN F O   1 
ATOM   4932 C CB  . ASN B 2 441 ? -25.51864 34.73898  -1.31336  1.000 163.57075 ? 476 ASN F CB  1 
ATOM   4933 C CG  . ASN B 2 441 ? -25.32194 35.80339  -0.24417  1.000 163.50623 ? 476 ASN F CG  1 
ATOM   4934 O OD1 . ASN B 2 441 ? -26.23737 36.56211  0.07629   1.000 170.22213 ? 476 ASN F OD1 1 
ATOM   4935 N ND2 . ASN B 2 441 ? -24.11997 35.85426  0.32088   1.000 150.74775 ? 476 ASN F ND2 1 
ATOM   4936 N N   . PHE B 2 442 ? -27.29913 31.99781  -2.35433  1.000 161.60689 ? 477 PHE F N   1 
ATOM   4937 C CA  . PHE B 2 442 ? -27.41613 31.03739  -3.45319  1.000 153.14954 ? 477 PHE F CA  1 
ATOM   4938 C C   . PHE B 2 442 ? -28.82073 30.91598  -4.04817  1.000 161.86569 ? 477 PHE F C   1 
ATOM   4939 O O   . PHE B 2 442 ? -29.02606 30.07737  -4.93551  1.000 160.75119 ? 477 PHE F O   1 
ATOM   4940 C CB  . PHE B 2 442 ? -26.90621 29.66005  -3.01004  1.000 145.04476 ? 477 PHE F CB  1 
ATOM   4941 C CG  . PHE B 2 442 ? -25.45974 29.66229  -2.57597  1.000 144.76422 ? 477 PHE F CG  1 
ATOM   4942 C CD1 . PHE B 2 442 ? -24.55344 30.53649  -3.15249  1.000 148.87282 ? 477 PHE F CD1 1 
ATOM   4943 C CD2 . PHE B 2 442 ? -25.00729 28.79688  -1.59374  1.000 140.77448 ? 477 PHE F CD2 1 
ATOM   4944 C CE1 . PHE B 2 442 ? -23.22501 30.55280  -2.75931  1.000 141.78015 ? 477 PHE F CE1 1 
ATOM   4945 C CE2 . PHE B 2 442 ? -23.67625 28.80871  -1.19767  1.000 140.10159 ? 477 PHE F CE2 1 
ATOM   4946 C CZ  . PHE B 2 442 ? -22.78636 29.68859  -1.78270  1.000 134.89986 ? 477 PHE F CZ  1 
ATOM   4947 N N   . TYR B 2 443 ? -29.78672 31.71817  -3.60063  1.000 169.41274 ? 478 TYR F N   1 
ATOM   4948 C CA  . TYR B 2 443 ? -31.18483 31.58487  -4.01755  1.000 177.60518 ? 478 TYR F CA  1 
ATOM   4949 C C   . TYR B 2 443 ? -31.67962 32.79002  -4.80824  1.000 183.19126 ? 478 TYR F C   1 
ATOM   4950 O O   . TYR B 2 443 ? -31.45610 33.93274  -4.39439  1.000 187.99473 ? 478 TYR F O   1 
ATOM   4951 C CB  . TYR B 2 443 ? -32.12564 31.35514  -2.81961  1.000 177.23841 ? 478 TYR F CB  1 
ATOM   4952 C CG  . TYR B 2 443 ? -32.07490 29.96886  -2.22045  1.000 173.95691 ? 478 TYR F CG  1 
ATOM   4953 C CD1 . TYR B 2 443 ? -32.79831 28.93125  -2.79646  1.000 174.57438 ? 478 TYR F CD1 1 
ATOM   4954 C CD2 . TYR B 2 443 ? -31.33936 29.69630  -1.07800  1.000 167.18701 ? 478 TYR F CD2 1 
ATOM   4955 C CE1 . TYR B 2 443 ? -32.77788 27.65928  -2.26610  1.000 174.55200 ? 478 TYR F CE1 1 
ATOM   4956 C CE2 . TYR B 2 443 ? -31.31364 28.41528  -0.53657  1.000 167.34451 ? 478 TYR F CE2 1 
ATOM   4957 C CZ  . TYR B 2 443 ? -32.03716 27.40233  -1.13985  1.000 171.71125 ? 478 TYR F CZ  1 
ATOM   4958 O OH  . TYR B 2 443 ? -32.03240 26.12453  -0.62621  1.000 172.56550 ? 478 TYR F OH  1 
ATOM   4959 N N   . ASP B 2 444 ? -32.33368 32.52994  -5.94710  1.000 180.45510 ? 479 ASP F N   1 
ATOM   4960 C CA  . ASP B 2 444 ? -32.94839 33.60478  -6.70730  1.000 180.61565 ? 479 ASP F CA  1 
ATOM   4961 C C   . ASP B 2 444 ? -34.20760 34.04508  -5.96550  1.000 186.45430 ? 479 ASP F C   1 
ATOM   4962 O O   . ASP B 2 444 ? -35.05681 33.20361  -5.65197  1.000 186.71033 ? 479 ASP F O   1 
ATOM   4963 C CB  . ASP B 2 444 ? -33.28582 33.13323  -8.11292  1.000 173.62016 ? 479 ASP F CB  1 
ATOM   4964 C CG  . ASP B 2 444 ? -33.97956 34.19939  -8.93713  1.000 179.99555 ? 479 ASP F CG  1 
ATOM   4965 O OD1 . ASP B 2 444 ? -33.29258 35.04731  -9.53900  1.000 174.80285 ? 479 ASP F OD1 1 
ATOM   4966 O OD2 . ASP B 2 444 ? -35.22895 34.20134  -8.98197  1.000 185.06205 ? 479 ASP F OD2 1 
ATOM   4967 N N   . PRO B 2 445 ? -34.36908 35.33932  -5.66610  1.000 187.90208 ? 480 PRO F N   1 
ATOM   4968 C CA  . PRO B 2 445 ? -35.54040 35.74742  -4.87052  1.000 186.45624 ? 480 PRO F CA  1 
ATOM   4969 C C   . PRO B 2 445 ? -36.88731 35.51072  -5.54981  1.000 183.49574 ? 480 PRO F C   1 
ATOM   4970 O O   . PRO B 2 445 ? -37.85154 35.10097  -4.88274  1.000 192.90968 ? 480 PRO F O   1 
ATOM   4971 C CB  . PRO B 2 445 ? -35.30874 37.25035  -4.66473  1.000 177.62979 ? 480 PRO F CB  1 
ATOM   4972 C CG  . PRO B 2 445 ? -33.85323 37.46740  -4.74890  1.000 174.95047 ? 480 PRO F CG  1 
ATOM   4973 C CD  . PRO B 2 445 ? -33.24536 36.27473  -5.49571  1.000 183.32481 ? 480 PRO F CD  1 
ATOM   4974 N N   . LEU B 2 446 ? -36.97284 35.75033  -6.85815  1.000 178.32945 ? 481 LEU F N   1 
ATOM   4975 C CA  . LEU B 2 446 ? -38.26262 35.69489  -7.55308  1.000 182.63746 ? 481 LEU F CA  1 
ATOM   4976 C C   . LEU B 2 446 ? -38.91737 34.31684  -7.49936  1.000 186.28564 ? 481 LEU F C   1 
ATOM   4977 O O   . LEU B 2 446 ? -40.13860 34.21730  -7.32607  1.000 182.71532 ? 481 LEU F O   1 
ATOM   4978 C CB  . LEU B 2 446 ? -38.14002 36.19446  -8.98498  1.000 177.39693 ? 481 LEU F CB  1 
ATOM   4979 C CG  . LEU B 2 446 ? -38.52480 37.67706  -9.07584  1.000 164.58686 ? 481 LEU F CG  1 
ATOM   4980 C CD1 . LEU B 2 446 ? -40.03734 37.79752  -8.97137  1.000 147.41611 ? 481 LEU F CD1 1 
ATOM   4981 C CD2 . LEU B 2 446 ? -37.85886 38.53748  -7.99735  1.000 153.15043 ? 481 LEU F CD2 1 
ATOM   4982 N N   . VAL B 2 447 ? -38.13916 33.24148  -7.64231  1.000 187.15806 ? 482 VAL F N   1 
ATOM   4983 C CA  . VAL B 2 447 ? -38.73481 31.91204  -7.71679  1.000 185.42682 ? 482 VAL F CA  1 
ATOM   4984 C C   . VAL B 2 447 ? -38.62458 31.16332  -6.39841  1.000 185.98065 ? 482 VAL F C   1 
ATOM   4985 O O   . VAL B 2 447 ? -38.90541 29.96054  -6.34214  1.000 179.58448 ? 482 VAL F O   1 
ATOM   4986 C CB  . VAL B 2 447 ? -38.11579 31.08910  -8.85571  1.000 178.93035 ? 482 VAL F CB  1 
ATOM   4987 C CG1 . VAL B 2 447 ? -38.42767 31.72811  -10.19155 1.000 175.97635 ? 482 VAL F CG1 1 
ATOM   4988 C CG2 . VAL B 2 447 ? -36.62031 30.92966  -8.63940  1.000 171.57212 ? 482 VAL F CG2 1 
ATOM   4989 N N   . PHE B 2 448 ? -38.23270 31.84703  -5.33524  1.000 196.21021 ? 483 PHE F N   1 
ATOM   4990 C CA  . PHE B 2 448 ? -38.08689 31.18511  -4.05340  1.000 199.59364 ? 483 PHE F CA  1 
ATOM   4991 C C   . PHE B 2 448 ? -39.48155 30.79832  -3.57427  1.000 197.03197 ? 483 PHE F C   1 
ATOM   4992 O O   . PHE B 2 448 ? -40.41692 31.59222  -3.71094  1.000 195.76036 ? 483 PHE F O   1 
ATOM   4993 C CB  . PHE B 2 448 ? -37.41205 32.13725  -3.07331  1.000 201.14673 ? 483 PHE F CB  1 
ATOM   4994 C CG  . PHE B 2 448 ? -36.97455 31.50593  -1.78881  1.000 193.04141 ? 483 PHE F CG  1 
ATOM   4995 C CD1 . PHE B 2 448 ? -35.97637 30.55764  -1.78472  1.000 188.45709 ? 483 PHE F CD1 1 
ATOM   4996 C CD2 . PHE B 2 448 ? -37.47946 31.95402  -0.57660  1.000 189.07522 ? 483 PHE F CD2 1 
ATOM   4997 C CE1 . PHE B 2 448 ? -35.55011 29.98975  -0.61312  1.000 190.16404 ? 483 PHE F CE1 1 
ATOM   4998 C CE2 . PHE B 2 448 ? -37.04566 31.40389  0.60657   1.000 195.00616 ? 483 PHE F CE2 1 
ATOM   4999 C CZ  . PHE B 2 448 ? -36.07748 30.41964  0.59154   1.000 197.27526 ? 483 PHE F CZ  1 
ATOM   5000 N N   . PRO B 2 449 ? -39.67149 29.62882  -3.00693  1.000 192.14748 ? 484 PRO F N   1 
ATOM   5001 C CA  . PRO B 2 449 ? -40.96990 29.42223  -2.36886  1.000 186.51893 ? 484 PRO F CA  1 
ATOM   5002 C C   . PRO B 2 449 ? -41.00650 30.04522  -0.98140  1.000 186.84100 ? 484 PRO F C   1 
ATOM   5003 O O   . PRO B 2 449 ? -40.46835 29.48318  -0.03080  1.000 189.14741 ? 484 PRO F O   1 
ATOM   5004 C CB  . PRO B 2 449 ? -41.13137 27.89161  -2.37811  1.000 180.99760 ? 484 PRO F CB  1 
ATOM   5005 C CG  . PRO B 2 449 ? -40.01668 27.36550  -3.21183  1.000 176.22084 ? 484 PRO F CG  1 
ATOM   5006 C CD  . PRO B 2 449 ? -38.91819 28.37246  -3.13001  1.000 183.96903 ? 484 PRO F CD  1 
ATOM   5007 N N   . SER B 2 450 ? -41.66409 31.20279  -0.84451  1.000 184.05381 ? 485 SER F N   1 
ATOM   5008 C CA  . SER B 2 450 ? -41.62820 31.93534  0.41878   1.000 181.32005 ? 485 SER F CA  1 
ATOM   5009 C C   . SER B 2 450 ? -42.83273 31.66657  1.31364   1.000 179.52359 ? 485 SER F C   1 
ATOM   5010 O O   . SER B 2 450 ? -42.77316 31.96364  2.51506   1.000 174.35340 ? 485 SER F O   1 
ATOM   5011 C CB  . SER B 2 450 ? -41.51637 33.44499  0.16119   1.000 174.07072 ? 485 SER F CB  1 
ATOM   5012 O OG  . SER B 2 450 ? -42.62409 33.93499  -0.58592  1.000 167.66218 ? 485 SER F OG  1 
ATOM   5013 N N   . ASN B 2 451 ? -43.91303 31.11313  0.76310   1.000 180.10499 ? 486 ASN F N   1 
ATOM   5014 C CA  . ASN B 2 451 ? -45.10781 30.76600  1.52411   1.000 177.21621 ? 486 ASN F CA  1 
ATOM   5015 C C   . ASN B 2 451 ? -45.14206 29.29759  1.93925   1.000 180.76369 ? 486 ASN F C   1 
ATOM   5016 O O   . ASN B 2 451 ? -46.10729 28.87326  2.58417   1.000 177.95548 ? 486 ASN F O   1 
ATOM   5017 C CB  . ASN B 2 451 ? -46.37672 31.10212  0.70995   1.000 169.06963 ? 486 ASN F CB  1 
ATOM   5018 C CG  . ASN B 2 451 ? -46.54439 32.60923  0.44921   1.000 161.62011 ? 486 ASN F CG  1 
ATOM   5019 O OD1 . ASN B 2 451 ? -45.77926 33.42424  0.96513   1.000 159.29215 ? 486 ASN F OD1 1 
ATOM   5020 N ND2 . ASN B 2 451 ? -47.53080 32.97412  -0.37448  1.000 158.18249 ? 486 ASN F ND2 1 
ATOM   5021 N N   . GLN B 2 452 ? -44.11806 28.51346  1.58676   1.000 182.96898 ? 487 GLN F N   1 
ATOM   5022 C CA  . GLN B 2 452 ? -44.17166 27.07467  1.81226   1.000 183.90625 ? 487 GLN F CA  1 
ATOM   5023 C C   . GLN B 2 452 ? -44.01783 26.70191  3.27953   1.000 182.37854 ? 487 GLN F C   1 
ATOM   5024 O O   . GLN B 2 452 ? -44.33542 25.56432  3.64644   1.000 183.35112 ? 487 GLN F O   1 
ATOM   5025 C CB  . GLN B 2 452 ? -43.10702 26.37065  0.96563   1.000 181.78897 ? 487 GLN F CB  1 
ATOM   5026 C CG  . GLN B 2 452 ? -41.70616 26.39534  1.54895   1.000 183.71666 ? 487 GLN F CG  1 
ATOM   5027 C CD  . GLN B 2 452 ? -40.65069 25.93523  0.54483   1.000 184.63793 ? 487 GLN F CD  1 
ATOM   5028 O OE1 . GLN B 2 452 ? -39.61035 26.57282  0.38202   1.000 191.14349 ? 487 GLN F OE1 1 
ATOM   5029 N NE2 . GLN B 2 452 ? -40.92361 24.82236  -0.13609  1.000 192.45957 ? 487 GLN F NE2 1 
ATOM   5030 N N   . PHE B 2 453 ? -43.55465 27.63089  4.11974   1.000 174.69284 ? 488 PHE F N   1 
ATOM   5031 C CA  . PHE B 2 453 ? -43.48328 27.44013  5.56964   1.000 178.78956 ? 488 PHE F CA  1 
ATOM   5032 C C   . PHE B 2 453 ? -42.52360 26.29925  5.90166   1.000 187.43490 ? 488 PHE F C   1 
ATOM   5033 O O   . PHE B 2 453 ? -41.40882 26.27599  5.37126   1.000 190.19837 ? 488 PHE F O   1 
ATOM   5034 C CB  . PHE B 2 453 ? -44.88841 27.19609  6.12749   1.000 179.35371 ? 488 PHE F CB  1 
ATOM   5035 C CG  . PHE B 2 453 ? -45.06793 27.60304  7.56024   1.000 183.60180 ? 488 PHE F CG  1 
ATOM   5036 C CD1 . PHE B 2 453 ? -45.22004 28.93743  7.91327   1.000 179.16737 ? 488 PHE F CD1 1 
ATOM   5037 C CD2 . PHE B 2 453 ? -45.11739 26.63994  8.55112   1.000 177.52302 ? 488 PHE F CD2 1 
ATOM   5038 C CE1 . PHE B 2 453 ? -45.38862 29.29462  9.23745   1.000 168.47364 ? 488 PHE F CE1 1 
ATOM   5039 C CE2 . PHE B 2 453 ? -45.28937 26.98633  9.87309   1.000 165.37270 ? 488 PHE F CE2 1 
ATOM   5040 C CZ  . PHE B 2 453 ? -45.42537 28.31901  10.21789  1.000 160.06019 ? 488 PHE F CZ  1 
ATOM   5041 N N   . ASP B 2 454 ? -42.91287 25.36837  6.77854   1.000 190.15833 ? 489 ASP F N   1 
ATOM   5042 C CA  . ASP B 2 454 ? -42.01349 24.28096  7.14137   1.000 183.84457 ? 489 ASP F CA  1 
ATOM   5043 C C   . ASP B 2 454 ? -41.72524 23.42092  5.91690   1.000 186.32975 ? 489 ASP F C   1 
ATOM   5044 O O   . ASP B 2 454 ? -42.63518 23.07200  5.15616   1.000 187.11618 ? 489 ASP F O   1 
ATOM   5045 C CB  . ASP B 2 454 ? -42.61709 23.40230  8.24880   1.000 173.40190 ? 489 ASP F CB  1 
ATOM   5046 C CG  . ASP B 2 454 ? -43.91822 22.74191  7.82857   1.000 176.16619 ? 489 ASP F CG  1 
ATOM   5047 O OD1 . ASP B 2 454 ? -44.77268 23.41979  7.22138   1.000 182.91756 ? 489 ASP F OD1 1 
ATOM   5048 O OD2 . ASP B 2 454 ? -44.07724 21.52801  8.09742   1.000 164.96866 ? 489 ASP F OD2 1 
ATOM   5049 N N   . ALA B 2 455 ? -40.45562 23.07403  5.71873   1.000 179.53474 ? 490 ALA F N   1 
ATOM   5050 C CA  . ALA B 2 455 ? -40.11234 22.37427  4.49471   1.000 172.59575 ? 490 ALA F CA  1 
ATOM   5051 C C   . ALA B 2 455 ? -38.75369 21.72186  4.62212   1.000 163.27805 ? 490 ALA F C   1 
ATOM   5052 O O   . ALA B 2 455 ? -37.84901 22.23610  5.28150   1.000 161.63595 ? 490 ALA F O   1 
ATOM   5053 C CB  . ALA B 2 455 ? -40.10761 23.31364  3.28115   1.000 174.68540 ? 490 ALA F CB  1 
ATOM   5054 N N   . SER B 2 456 ? -38.62597 20.59681  3.94686   1.000 163.67401 ? 491 SER F N   1 
ATOM   5055 C CA  . SER B 2 456 ? -37.38183 19.86526  3.88303   1.000 165.03908 ? 491 SER F CA  1 
ATOM   5056 C C   . SER B 2 456 ? -36.50383 20.48535  2.80608   1.000 175.60435 ? 491 SER F C   1 
ATOM   5057 O O   . SER B 2 456 ? -36.98635 21.19100  1.91650   1.000 177.37319 ? 491 SER F O   1 
ATOM   5058 C CB  . SER B 2 456 ? -37.65183 18.38479  3.62780   1.000 163.91687 ? 491 SER F CB  1 
ATOM   5059 O OG  . SER B 2 456 ? -36.44712 17.69932  3.38349   1.000 159.57758 ? 491 SER F OG  1 
ATOM   5060 N N   . ILE B 2 457 ? -35.19603 20.24414  2.91675   1.000 177.28827 ? 492 ILE F N   1 
ATOM   5061 C CA  . ILE B 2 457 ? -34.25916 20.77284  1.92614   1.000 178.79888 ? 492 ILE F CA  1 
ATOM   5062 C C   . ILE B 2 457 ? -34.60163 20.23052  0.54062   1.000 180.63970 ? 492 ILE F C   1 
ATOM   5063 O O   . ILE B 2 457 ? -34.68900 20.98934  -0.43559  1.000 183.59629 ? 492 ILE F O   1 
ATOM   5064 C CB  . ILE B 2 457 ? -32.79409 20.49735  2.32444   1.000 175.08175 ? 492 ILE F CB  1 
ATOM   5065 C CG1 . ILE B 2 457 ? -31.86002 21.24743  1.37465   1.000 162.81385 ? 492 ILE F CG1 1 
ATOM   5066 C CG2 . ILE B 2 457 ? -32.46439 19.00678  2.37342   1.000 171.90151 ? 492 ILE F CG2 1 
ATOM   5067 C CD1 . ILE B 2 457 ? -32.09061 22.74346  1.40060   1.000 160.99706 ? 492 ILE F CD1 1 
ATOM   5068 N N   . SER B 2 458 ? -34.82087 18.91604  0.43451   1.000 178.95421 ? 493 SER F N   1 
ATOM   5069 C CA  . SER B 2 458 ? -35.18029 18.32684  -0.85190  1.000 175.92649 ? 493 SER F CA  1 
ATOM   5070 C C   . SER B 2 458 ? -36.53164 18.84132  -1.35200  1.000 177.68320 ? 493 SER F C   1 
ATOM   5071 O O   . SER B 2 458 ? -36.75240 18.90604  -2.56601  1.000 180.90879 ? 493 SER F O   1 
ATOM   5072 C CB  . SER B 2 458 ? -35.21321 16.80410  -0.73870  1.000 158.45796 ? 493 SER F CB  1 
ATOM   5073 O OG  . SER B 2 458 ? -33.97303 16.27025  -0.28142  1.000 135.00705 ? 493 SER F OG  1 
ATOM   5074 N N   . GLN B 2 459 ? -37.44375 19.23459  -0.45353  1.000 177.99046 ? 494 GLN F N   1 
ATOM   5075 C CA  . GLN B 2 459 ? -38.70323 19.82570  -0.91680  1.000 184.45978 ? 494 GLN F CA  1 
ATOM   5076 C C   . GLN B 2 459 ? -38.43643 21.16107  -1.61618  1.000 189.46378 ? 494 GLN F C   1 
ATOM   5077 O O   . GLN B 2 459 ? -39.02555 21.44926  -2.66729  1.000 195.01298 ? 494 GLN F O   1 
ATOM   5078 C CB  . GLN B 2 459 ? -39.70356 19.98389  0.22882   1.000 179.46290 ? 494 GLN F CB  1 
ATOM   5079 C CG  . GLN B 2 459 ? -40.88773 20.88164  -0.14878  1.000 182.44707 ? 494 GLN F CG  1 
ATOM   5080 C CD  . GLN B 2 459 ? -41.75593 21.24880  1.02038   1.000 184.36923 ? 494 GLN F CD  1 
ATOM   5081 O OE1 . GLN B 2 459 ? -41.63608 20.66907  2.09618   1.000 183.33003 ? 494 GLN F OE1 1 
ATOM   5082 N NE2 . GLN B 2 459 ? -42.62429 22.23723  0.82678   1.000 186.45506 ? 494 GLN F NE2 1 
ATOM   5083 N N   . VAL B 2 460 ? -37.56627 21.99447  -1.03520  1.000 185.30363 ? 495 VAL F N   1 
ATOM   5084 C CA  . VAL B 2 460 ? -37.28555 23.29700  -1.62634  1.000 182.87421 ? 495 VAL F CA  1 
ATOM   5085 C C   . VAL B 2 460 ? -36.54338 23.10219  -2.94180  1.000 190.86864 ? 495 VAL F C   1 
ATOM   5086 O O   . VAL B 2 460 ? -36.75994 23.83884  -3.91215  1.000 190.35386 ? 495 VAL F O   1 
ATOM   5087 C CB  . VAL B 2 460 ? -36.47964 24.17411  -0.65168  1.000 176.03807 ? 495 VAL F CB  1 
ATOM   5088 C CG1 . VAL B 2 460 ? -36.14738 25.50042  -1.29545  1.000 169.25884 ? 495 VAL F CG1 1 
ATOM   5089 C CG2 . VAL B 2 460 ? -37.24490 24.36795  0.63332   1.000 173.00759 ? 495 VAL F CG2 1 
ATOM   5090 N N   . ASN B 2 461 ? -35.60579 22.15188  -2.97592  1.000 194.45549 ? 496 ASN F N   1 
ATOM   5091 C CA  . ASN B 2 461 ? -34.84997 21.91138  -4.20148  1.000 191.13813 ? 496 ASN F CA  1 
ATOM   5092 C C   . ASN B 2 461 ? -35.79043 21.42942  -5.31055  1.000 198.96332 ? 496 ASN F C   1 
ATOM   5093 O O   . ASN B 2 461 ? -35.62731 21.79184  -6.48491  1.000 197.51417 ? 496 ASN F O   1 
ATOM   5094 C CB  . ASN B 2 461 ? -33.73761 20.89245  -3.94096  1.000 181.36606 ? 496 ASN F CB  1 
ATOM   5095 C CG  . ASN B 2 461 ? -32.64727 21.44658  -3.04728  1.000 183.39770 ? 496 ASN F CG  1 
ATOM   5096 O OD1 . ASN B 2 461 ? -32.51045 22.66345  -2.90699  1.000 177.05924 ? 496 ASN F OD1 1 
ATOM   5097 N ND2 . ASN B 2 461 ? -31.87530 20.56016  -2.42289  1.000 190.93164 ? 496 ASN F ND2 1 
ATOM   5098 N N   . GLU B 2 462 ? -36.79322 20.60511  -4.95423  1.000 204.30857 ? 497 GLU F N   1 
ATOM   5099 C CA  . GLU B 2 462 ? -37.77237 20.18231  -5.95388  1.000 204.69730 ? 497 GLU F CA  1 
ATOM   5100 C C   . GLU B 2 462 ? -38.63978 21.34137  -6.41058  1.000 202.25778 ? 497 GLU F C   1 
ATOM   5101 O O   . GLU B 2 462 ? -39.03470 21.40048  -7.57899  1.000 207.71119 ? 497 GLU F O   1 
ATOM   5102 C CB  . GLU B 2 462 ? -38.65365 19.06367  -5.41055  1.000 202.82348 ? 497 GLU F CB  1 
ATOM   5103 C CG  . GLU B 2 462 ? -37.99958 17.70187  -5.32926  1.000 202.64652 ? 497 GLU F CG  1 
ATOM   5104 C CD  . GLU B 2 462 ? -37.82084 17.05201  -6.68443  1.000 194.51678 ? 497 GLU F CD  1 
ATOM   5105 O OE1 . GLU B 2 462 ? -38.27177 17.65202  -7.68138  1.000 196.52983 ? 497 GLU F OE1 1 
ATOM   5106 O OE2 . GLU B 2 462 ? -37.29503 15.91034  -6.73703  1.000 181.28484 ? 497 GLU F OE2 1 
ATOM   5107 N N   . LYS B 2 463 ? -38.96530 22.26000  -5.49403  1.000 195.77032 ? 498 LYS F N   1 
ATOM   5108 C CA  . LYS B 2 463 ? -39.71639 23.44868  -5.88098  1.000 190.23397 ? 498 LYS F CA  1 
ATOM   5109 C C   . LYS B 2 463 ? -38.90060 24.34548  -6.82119  1.000 197.03088 ? 498 LYS F C   1 
ATOM   5110 O O   . LYS B 2 463 ? -39.47074 25.01229  -7.69618  1.000 196.15491 ? 498 LYS F O   1 
ATOM   5111 C CB  . LYS B 2 463 ? -40.16342 24.20802  -4.63806  1.000 181.34572 ? 498 LYS F CB  1 
ATOM   5112 C CG  . LYS B 2 463 ? -41.29518 23.52427  -3.85804  1.000 175.25481 ? 498 LYS F CG  1 
ATOM   5113 C CD  . LYS B 2 463 ? -42.58431 23.38371  -4.63881  1.000 155.02118 ? 498 LYS F CD  1 
ATOM   5114 C CE  . LYS B 2 463 ? -43.15599 24.72345  -5.01102  1.000 145.28151 ? 498 LYS F CE  1 
ATOM   5115 N NZ  . LYS B 2 463 ? -43.55725 25.52965  -3.82901  1.000 138.93926 ? 498 LYS F NZ  1 
ATOM   5116 N N   . ILE B 2 464 ? -37.57027 24.31971  -6.70721  1.000 200.31832 ? 499 ILE F N   1 
ATOM   5117 C CA  . ILE B 2 464 ? -36.73427 25.09863  -7.62411  1.000 199.12025 ? 499 ILE F CA  1 
ATOM   5118 C C   . ILE B 2 464 ? -36.63998 24.41030  -8.98846  1.000 207.43927 ? 499 ILE F C   1 
ATOM   5119 O O   . ILE B 2 464 ? -36.63664 25.07178  -10.03981 1.000 214.24540 ? 499 ILE F O   1 
ATOM   5120 C CB  . ILE B 2 464 ? -35.33972 25.31155  -7.00986  1.000 189.87372 ? 499 ILE F CB  1 
ATOM   5121 C CG1 . ILE B 2 464 ? -35.42204 26.06928  -5.68813  1.000 180.91446 ? 499 ILE F CG1 1 
ATOM   5122 C CG2 . ILE B 2 464 ? -34.44055 26.05915  -7.98276  1.000 186.40443 ? 499 ILE F CG2 1 
ATOM   5123 C CD1 . ILE B 2 464 ? -34.09212 26.18580  -5.01885  1.000 171.87981 ? 499 ILE F CD1 1 
ATOM   5124 N N   . ASN B 2 465 ? -36.56069 23.07777  -9.00814  1.000 202.47463 ? 500 ASN F N   1 
ATOM   5125 C CA  . ASN B 2 465 ? -36.58015 22.35488  -10.28411 1.000 194.88572 ? 500 ASN F CA  1 
ATOM   5126 C C   . ASN B 2 465 ? -37.95013 22.51331  -10.96621 1.000 198.80715 ? 500 ASN F C   1 
ATOM   5127 O O   . ASN B 2 465 ? -38.02422 22.63067  -12.19958 1.000 203.46060 ? 500 ASN F O   1 
ATOM   5128 C CB  . ASN B 2 465 ? -36.12331 20.90306  -10.10169 1.000 182.04205 ? 500 ASN F CB  1 
ATOM   5129 C CG  . ASN B 2 465 ? -34.59205 20.79666  -9.96122  1.000 180.32354 ? 500 ASN F CG  1 
ATOM   5130 O OD1 . ASN B 2 465 ? -33.93066 21.76612  -9.59544  1.000 185.08722 ? 500 ASN F OD1 1 
ATOM   5131 N ND2 . ASN B 2 465 ? -34.03103 19.62009  -10.27079 1.000 174.58865 ? 500 ASN F ND2 1 
ATOM   5132 N N   . GLN B 2 466 ? -39.01569 22.67534  -10.17054 1.000 200.11547 ? 501 GLN F N   1 
ATOM   5133 C CA  . GLN B 2 466 ? -40.34228 22.91021  -10.73118 1.000 199.19561 ? 501 GLN F CA  1 
ATOM   5134 C C   . GLN B 2 466 ? -40.44414 24.32568  -11.27286 1.000 207.09339 ? 501 GLN F C   1 
ATOM   5135 O O   . GLN B 2 466 ? -41.10821 24.54523  -12.29123 1.000 213.13970 ? 501 GLN F O   1 
ATOM   5136 C CB  . GLN B 2 466 ? -41.43370 22.74209  -9.66550  1.000 195.20641 ? 501 GLN F CB  1 
ATOM   5137 C CG  . GLN B 2 466 ? -41.62878 21.38304  -9.02898  1.000 189.91993 ? 501 GLN F CG  1 
ATOM   5138 C CD  . GLN B 2 466 ? -42.69401 21.41088  -7.93216  1.000 182.49134 ? 501 GLN F CD  1 
ATOM   5139 O OE1 . GLN B 2 466 ? -43.40224 22.40390  -7.76253  1.000 180.73300 ? 501 GLN F OE1 1 
ATOM   5140 N NE2 . GLN B 2 466 ? -42.78543 20.32663  -7.16245  1.000 174.63694 ? 501 GLN F NE2 1 
ATOM   5141 N N   . SER B 2 467 ? -39.73306 25.28392  -10.67027 1.000 211.31393 ? 502 SER F N   1 
ATOM   5142 C CA  . SER B 2 467 ? -39.79952 26.62744  -11.23481 1.000 211.46054 ? 502 SER F CA  1 
ATOM   5143 C C   . SER B 2 467 ? -38.92896 26.74391  -12.48382 1.000 210.36148 ? 502 SER F C   1 
ATOM   5144 O O   . SER B 2 467 ? -39.26003 27.52171  -13.39570 1.000 204.46497 ? 502 SER F O   1 
ATOM   5145 C CB  . SER B 2 467 ? -39.37267 27.68065  -10.20275 1.000 209.75706 ? 502 SER F CB  1 
ATOM   5146 O OG  . SER B 2 467 ? -38.04740 27.46865  -9.74264  1.000 214.06605 ? 502 SER F OG  1 
ATOM   5147 N N   . LEU B 2 468 ? -37.89920 25.89763  -12.61967 1.000 215.03262 ? 503 LEU F N   1 
ATOM   5148 C CA  . LEU B 2 468 ? -37.16470 25.96962  -13.87785 1.000 212.05839 ? 503 LEU F CA  1 
ATOM   5149 C C   . LEU B 2 468 ? -37.95941 25.27279  -14.97309 1.000 208.54115 ? 503 LEU F C   1 
ATOM   5150 O O   . LEU B 2 468 ? -37.88221 25.66496  -16.15219 1.000 201.01736 ? 503 LEU F O   1 
ATOM   5151 C CB  . LEU B 2 468 ? -35.79058 25.30351  -13.75296 1.000 204.99637 ? 503 LEU F CB  1 
ATOM   5152 C CG  . LEU B 2 468 ? -34.60210 25.94383  -13.03156 1.000 202.80488 ? 503 LEU F CG  1 
ATOM   5153 C CD1 . LEU B 2 468 ? -33.39989 25.00991  -13.09583 1.000 192.22368 ? 503 LEU F CD1 1 
ATOM   5154 C CD2 . LEU B 2 468 ? -34.24916 27.29189  -13.62149 1.000 205.24868 ? 503 LEU F CD2 1 
ATOM   5155 N N   . ALA B 2 469 ? -38.76957 24.27309  -14.59776 1.000 212.25989 ? 504 ALA F N   1 
ATOM   5156 C CA  . ALA B 2 469 ? -39.64419 23.69400  -15.60414 1.000 199.16899 ? 504 ALA F CA  1 
ATOM   5157 C C   . ALA B 2 469 ? -40.72335 24.69889  -15.98746 1.000 197.87942 ? 504 ALA F C   1 
ATOM   5158 O O   . ALA B 2 469 ? -41.17319 24.71928  -17.13789 1.000 184.42985 ? 504 ALA F O   1 
ATOM   5159 C CB  . ALA B 2 469 ? -40.25657 22.38974  -15.09456 1.000 192.02888 ? 504 ALA F CB  1 
ATOM   5160 N N   . PHE B 2 470 ? -41.13623 25.54650  -15.02979 1.000 210.35328 ? 505 PHE F N   1 
ATOM   5161 C CA  . PHE B 2 470 ? -42.10664 26.60811  -15.29332 1.000 205.83885 ? 505 PHE F CA  1 
ATOM   5162 C C   . PHE B 2 470 ? -41.54317 27.71516  -16.17543 1.000 201.66152 ? 505 PHE F C   1 
ATOM   5163 O O   . PHE B 2 470 ? -42.32251 28.46552  -16.77434 1.000 193.11360 ? 505 PHE F O   1 
ATOM   5164 C CB  . PHE B 2 470 ? -42.60487 27.25877  -13.99215 1.000 204.45430 ? 505 PHE F CB  1 
ATOM   5165 C CG  . PHE B 2 470 ? -43.26139 26.30694  -13.02983 1.000 206.53035 ? 505 PHE F CG  1 
ATOM   5166 C CD1 . PHE B 2 470 ? -43.93703 25.18938  -13.48415 1.000 202.80631 ? 505 PHE F CD1 1 
ATOM   5167 C CD2 . PHE B 2 470 ? -43.23397 26.55681  -11.66416 1.000 204.26621 ? 505 PHE F CD2 1 
ATOM   5168 C CE1 . PHE B 2 470 ? -44.53911 24.31646  -12.59606 1.000 197.35995 ? 505 PHE F CE1 1 
ATOM   5169 C CE2 . PHE B 2 470 ? -43.83734 25.68826  -10.77082 1.000 197.21166 ? 505 PHE F CE2 1 
ATOM   5170 C CZ  . PHE B 2 470 ? -44.49242 24.56878  -11.23786 1.000 194.53091 ? 505 PHE F CZ  1 
ATOM   5171 N N   . ILE B 2 471 ? -40.21751 27.83168  -16.27627 1.000 205.12007 ? 506 ILE F N   1 
ATOM   5172 C CA  . ILE B 2 471 ? -39.65238 28.87010  -17.14062 1.000 197.69992 ? 506 ILE F CA  1 
ATOM   5173 C C   . ILE B 2 471 ? -39.23894 28.36364  -18.52020 1.000 190.78588 ? 506 ILE F C   1 
ATOM   5174 O O   . ILE B 2 471 ? -39.22125 29.14295  -19.47986 1.000 188.03063 ? 506 ILE F O   1 
ATOM   5175 C CB  . ILE B 2 471 ? -38.45441 29.58705  -16.48362 1.000 196.84651 ? 506 ILE F CB  1 
ATOM   5176 C CG1 . ILE B 2 471 ? -37.20625 28.70239  -16.48914 1.000 190.31012 ? 506 ILE F CG1 1 
ATOM   5177 C CG2 . ILE B 2 471 ? -38.80227 30.05784  -15.07944 1.000 199.65083 ? 506 ILE F CG2 1 
ATOM   5178 C CD1 . ILE B 2 471 ? -35.99362 29.36785  -15.89124 1.000 177.81240 ? 506 ILE F CD1 1 
ATOM   5179 N N   . ARG B 2 472 ? -38.89987 27.07754  -18.65465 1.000 189.49100 ? 507 ARG F N   1 
ATOM   5180 C CA  . ARG B 2 472 ? -38.49195 26.59255  -19.97795 1.000 185.07730 ? 507 ARG F CA  1 
ATOM   5181 C C   . ARG B 2 472 ? -39.62040 26.66585  -21.00860 1.000 185.77650 ? 507 ARG F C   1 
ATOM   5182 O O   . ARG B 2 472 ? -39.40781 27.11437  -22.14220 1.000 179.08246 ? 507 ARG F O   1 
ATOM   5183 C CB  . ARG B 2 472 ? -37.96112 25.16140  -19.88913 1.000 180.79715 ? 507 ARG F CB  1 
ATOM   5184 C CG  . ARG B 2 472 ? -36.46276 25.06082  -20.07135 1.000 174.73921 ? 507 ARG F CG  1 
ATOM   5185 C CD  . ARG B 2 472 ? -35.71801 25.83546  -19.00861 1.000 176.64512 ? 507 ARG F CD  1 
ATOM   5186 N NE  . ARG B 2 472 ? -34.30409 25.48357  -18.99484 1.000 172.43005 ? 507 ARG F NE  1 
ATOM   5187 C CZ  . ARG B 2 472 ? -33.77131 24.55703  -18.21044 1.000 174.43830 ? 507 ARG F CZ  1 
ATOM   5188 N NH1 . ARG B 2 472 ? -34.50943 23.86468  -17.35839 1.000 185.92163 ? 507 ARG F NH1 1 
ATOM   5189 N NH2 . ARG B 2 472 ? -32.46527 24.31784  -18.28319 1.000 165.31195 ? 507 ARG F NH2 1 
ATOM   5190 N N   . LYS B 2 473 ? -40.82574 26.23155  -20.63959 1.000 189.68085 ? 508 LYS F N   1 
ATOM   5191 C CA  . LYS B 2 473 ? -41.94430 26.25912  -21.58364 1.000 182.70298 ? 508 LYS F CA  1 
ATOM   5192 C C   . LYS B 2 473 ? -42.40313 27.66986  -21.94902 1.000 180.19978 ? 508 LYS F C   1 
ATOM   5193 O O   . LYS B 2 473 ? -42.90422 27.87795  -23.06092 1.000 176.24889 ? 508 LYS F O   1 
ATOM   5194 C CB  . LYS B 2 473 ? -43.10449 25.43009  -21.03479 1.000 181.24593 ? 508 LYS F CB  1 
ATOM   5195 C CG  . LYS B 2 473 ? -42.96557 23.94859  -21.36119 1.000 172.32172 ? 508 LYS F CG  1 
ATOM   5196 C CD  . LYS B 2 473 ? -41.87472 23.29317  -20.53388 1.000 170.20827 ? 508 LYS F CD  1 
ATOM   5197 C CE  . LYS B 2 473 ? -41.82542 21.79640  -20.75160 1.000 146.03364 ? 508 LYS F CE  1 
ATOM   5198 N NZ  . LYS B 2 473 ? -40.80903 21.15574  -19.87626 1.000 117.04585 ? 508 LYS F NZ  1 
ATOM   5199 N N   . SER B 2 474 ? -42.25369 28.64370  -21.05626 1.000 183.00828 ? 509 SER F N   1 
ATOM   5200 C CA  . SER B 2 474 ? -42.67948 30.00776  -21.37843 1.000 171.94473 ? 509 SER F CA  1 
ATOM   5201 C C   . SER B 2 474 ? -41.48914 30.89790  -21.71262 1.000 160.22808 ? 509 SER F C   1 
ATOM   5202 O O   . SER B 2 474 ? -41.28099 31.25310  -22.87326 1.000 149.80320 ? 509 SER F O   1 
ATOM   5203 C CB  . SER B 2 474 ? -43.47551 30.62001  -20.22103 1.000 173.25986 ? 509 SER F CB  1 
ATOM   5204 O OG  . SER B 2 474 ? -42.69284 30.70909  -19.04283 1.000 174.00952 ? 509 SER F OG  1 
HETATM 5205 C C1  . NAG C 3 .   ? -32.59689 19.40165  -10.18697 1.000 172.76436 ? 601 NAG F C1  1 
HETATM 5206 C C2  . NAG C 3 .   ? -32.22628 18.17629  -9.33117  1.000 175.09092 ? 601 NAG F C2  1 
HETATM 5207 C C3  . NAG C 3 .   ? -30.71088 17.99661  -9.29088  1.000 164.37854 ? 601 NAG F C3  1 
HETATM 5208 C C4  . NAG C 3 .   ? -30.14912 17.91346  -10.70259 1.000 158.70401 ? 601 NAG F C4  1 
HETATM 5209 C C5  . NAG C 3 .   ? -30.53923 19.15619  -11.49239 1.000 157.62633 ? 601 NAG F C5  1 
HETATM 5210 C C6  . NAG C 3 .   ? -30.07989 19.09914  -12.93268 1.000 140.42124 ? 601 NAG F C6  1 
HETATM 5211 C C7  . NAG C 3 .   ? -33.93096 17.77557  -7.60977  1.000 190.44907 ? 601 NAG F C7  1 
HETATM 5212 C C8  . NAG C 3 .   ? -34.33567 18.01439  -6.18568  1.000 186.48227 ? 601 NAG F C8  1 
HETATM 5213 N N2  . NAG C 3 .   ? -32.76017 18.30239  -7.98385  1.000 185.67522 ? 601 NAG F N2  1 
HETATM 5214 O O3  . NAG C 3 .   ? -30.38875 16.80655  -8.58174  1.000 153.02756 ? 601 NAG F O3  1 
HETATM 5215 O O4  . NAG C 3 .   ? -28.73098 17.79657  -10.67020 1.000 141.14257 ? 601 NAG F O4  1 
HETATM 5216 O O5  . NAG C 3 .   ? -31.97067 19.29054  -11.50939 1.000 165.84959 ? 601 NAG F O5  1 
HETATM 5217 O O6  . NAG C 3 .   ? -29.04562 18.14040  -13.11608 1.000 125.52484 ? 601 NAG F O6  1 
HETATM 5218 O O7  . NAG C 3 .   ? -34.62988 17.13097  -8.38496  1.000 193.06024 ? 601 NAG F O7  1 
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